## Tue Feb 11 18:31:51 2025 ## emapper-2.1.12 ## /data/home/zhuyingjie/miniforge3/envs/eggnog/bin/emapper.py -i /data/shared_data/ZYJ_Metagenome/metagenome_bucong/mmseqs/SRR17522550//SRR17522550_p_cluster_rep_seq.fasta --output SRR17522550 --data_dir /data/software/eggnog_database -m diamond --sensmode fast --output_dir /data/shared_data/ZYJ_Metagenome/metagenome_bucong/eggnog/SRR17522550 --temp_dir /data/software/eggnog_database/temp --excel --dbmem --cpu 24 ## #query seed_ortholog evalue score eggNOG_OGs max_annot_lvl COG_category Description Preferred_name GOs EC KEGG_ko KEGG_Pathway KEGG_Module KEGG_Reaction KEGG_rclass BRITE KEGG_TC CAZy BiGG_Reaction PFAMs k141_17896_2 1223523.H340_26549 1.52e-16 74.7 2EREK@1|root,33J04@2|Bacteria,2IRRD@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k141_9560_1 42565.FP66_08410 1.46e-99 308.0 COG1298@1|root,COG1298@2|Bacteria,1MUF3@1224|Proteobacteria,1RMSM@1236|Gammaproteobacteria,1XH92@135619|Oceanospirillales 135619|Oceanospirillales N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin flhA - - ko:K02400 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 - - FHIPEP k141_1213_2 218284.CCDN010000001_gene992 1.51e-12 63.2 28NYH@1|root,2ZBVN@2|Bacteria,1V1T3@1239|Firmicutes,4HHZS@91061|Bacilli,1ZFKZ@1386|Bacillus 91061|Bacilli S Belongs to the UPF0403 family yqiW - - - - - - - - - - - Disulph_isomer k141_26216_1 218284.CCDN010000002_gene2015 2.24e-203 572.0 COG0154@1|root,COG0154@2|Bacteria,1TP0C@1239|Firmicutes,4HBAZ@91061|Bacilli,1ZAT1@1386|Bacillus 91061|Bacilli J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) gatA - 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Amidase k141_30974_3 360095.BARBAKC583_1140 4.75e-08 58.5 COG1261@1|root,COG1261@2|Bacteria,1MZIR@1224|Proteobacteria,2UFXT@28211|Alphaproteobacteria,48U1T@772|Bartonellaceae 28211|Alphaproteobacteria N Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly flgA - - ko:K02386 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - ChapFlgA k141_30974_4 1517681.HW45_22565 1.52e-231 659.0 COG1298@1|root,COG1298@2|Bacteria,1MUF3@1224|Proteobacteria,1RMSM@1236|Gammaproteobacteria,1XSP7@135623|Vibrionales 135623|Vibrionales N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin - - - ko:K02400 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 - - FHIPEP k141_11929_1 218284.CCDN010000001_gene947 3.98e-35 127.0 COG1752@1|root,COG1752@2|Bacteria,1TRJW@1239|Firmicutes,4HB8J@91061|Bacilli,1ZC13@1386|Bacillus 91061|Bacilli S esterase of the alpha-beta hydrolase superfamily yqhO GO:0003674,GO:0003824,GO:0016787 - ko:K07001 - - - - ko00000 - - - Patatin k141_11929_2 218284.CCDN010000001_gene946 0.0 946.0 COG0209@1|root,COG0209@2|Bacteria,1TPFH@1239|Firmicutes,4HA07@91061|Bacilli,1ZCST@1386|Bacillus 91061|Bacilli F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen nrdZ - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_lgC,Ribonuc_red_lgN k141_22648_2 207954.MED92_04659 6.09e-19 90.1 COG3079@1|root,COG3079@2|Bacteria,1N7W0@1224|Proteobacteria,1SCPW@1236|Gammaproteobacteria,1XK9X@135619|Oceanospirillales 135619|Oceanospirillales S Belongs to the UPF0149 family - - - ko:K09895 - - - - ko00000 - - - UPF0149 k141_21460_1 218284.CCDN010000007_gene3827 4.85e-117 354.0 COG4863@1|root,COG4863@2|Bacteria,1UV48@1239|Firmicutes,4HF30@91061|Bacilli,1ZD30@1386|Bacillus 91061|Bacilli S protein conserved in bacteria yycH - - - - - - - - - - - YycH k141_21460_2 218284.CCDN010000007_gene3826 1.38e-193 551.0 COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HA52@91061|Bacilli,1ZCQI@1386|Bacillus 91061|Bacilli T Histidine kinase vicK - 2.7.13.3 ko:K07652 ko02020,map02020 M00459 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,PAS,PAS_9 k141_9561_1 1279017.AQYJ01000024_gene1151 7.09e-29 114.0 COG4623@1|root,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,1RM8W@1236|Gammaproteobacteria,4640D@72275|Alteromonadaceae 1236|Gammaproteobacteria M Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella mltF GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009279,GO:0016020,GO:0016740,GO:0016757,GO:0019867,GO:0030203,GO:0030312,GO:0030313,GO:0031975,GO:0043170,GO:0044462,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - ko:K18691 - - - - ko00000,ko01000,ko01011 - - iBWG_1329.BWG_2322,iEC042_1314.EC042_2762,iECDH1ME8569_1439.ECDH1ME8569_2485,iECNA114_1301.ECNA114_2631,iECP_1309.ECP_2560,iECSF_1327.ECSF_2397,iECW_1372.ECW_m2786,iEKO11_1354.EKO11_1175,iEcDH1_1363.EcDH1_1110,iEcHS_1320.EcHS_A2711,iEcolC_1368.EcolC_1119,iG2583_1286.G2583_3089,iJO1366.b2558,iSFxv_1172.SFxv_2861,iUMN146_1321.UM146_03930,iUMNK88_1353.UMNK88_3212,iUTI89_1310.UTI89_C2878,iWFL_1372.ECW_m2786,iY75_1357.Y75_RS13345 SBP_bac_3,SLT k141_69_2 218284.CCDN010000006_gene3626 1.94e-256 716.0 COG0745@1|root,COG2199@1|root,COG0745@2|Bacteria,COG3706@2|Bacteria,1TSW8@1239|Firmicutes,4HBT1@91061|Bacilli,1ZCZQ@1386|Bacillus 91061|Bacilli T diguanylate cyclase - - - - - - - - - - - - GGDEF,Hpt,Response_reg k141_36899_11 1116375.VEJY3_05975 0.0 1008.0 COG0076@1|root,COG0076@2|Bacteria,1MWUX@1224|Proteobacteria,1RQ8G@1236|Gammaproteobacteria,1XTEY@135623|Vibrionales 135623|Vibrionales E COG0076 Glutamate decarboxylase and related PLP-dependent proteins - GO:0003674,GO:0003824,GO:0004068,GO:0016829,GO:0016830,GO:0016831 4.1.1.15 ko:K01580 ko00250,ko00410,ko00430,ko00650,ko01100,ko01110,ko01120,ko02024,ko04727,ko04940,map00250,map00410,map00430,map00650,map01100,map01110,map01120,map02024,map04727,map04940 M00027 R00261,R00489,R01682,R02466 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Pyridoxal_deC k141_36899_12 1116375.VEJY3_05980 5.5e-111 320.0 2BG53@1|root,32A1V@2|Bacteria,1QJKM@1224|Proteobacteria,1THM8@1236|Gammaproteobacteria,1XWNB@135623|Vibrionales 135623|Vibrionales - - VC1150 - - - - - - - - - - - - k141_36899_13 1116375.VEJY3_05985 2.34e-186 522.0 COG2431@1|root,COG2431@2|Bacteria,1MYMF@1224|Proteobacteria,1RP7N@1236|Gammaproteobacteria,1XUYP@135623|Vibrionales 135623|Vibrionales S membrane ybjE - - - - - - - - - - - Lys_export k141_36899_14 1116375.VEJY3_05990 3.04e-189 529.0 COG1639@1|root,COG1639@2|Bacteria,1N7EN@1224|Proteobacteria,1RT8G@1236|Gammaproteobacteria,1XUWE@135623|Vibrionales 135623|Vibrionales T Signal transduction protein - - - - - - - - - - - - HDOD k141_36899_15 1116375.VEJY3_05995 7.24e-130 369.0 COG3070@1|root,COG3070@2|Bacteria,1QJGH@1224|Proteobacteria,1THG9@1236|Gammaproteobacteria,1XVKC@135623|Vibrionales 135623|Vibrionales K COG3070 Regulator of competence-specific genes VV1446 GO:0006810,GO:0007154,GO:0008150,GO:0009290,GO:0009292,GO:0009294,GO:0009605,GO:0009987,GO:0009991,GO:0015931,GO:0030420,GO:0031668,GO:0044764,GO:0050657,GO:0050896,GO:0051027,GO:0051179,GO:0051234,GO:0051704,GO:0051716,GO:0071496,GO:0071702,GO:0071705,GO:0098657 - ko:K07343 - - - - ko00000 - - - TfoX_C,TfoX_N k141_36899_16 1116375.VEJY3_06000 6.32e-120 343.0 2B0QJ@1|root,31T2K@2|Bacteria,1QJDY@1224|Proteobacteria,1THD8@1236|Gammaproteobacteria,1XU73@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_36899_17 1116375.VEJY3_06005 2.01e-106 308.0 COG0784@1|root,COG0784@2|Bacteria,1MYIP@1224|Proteobacteria,1S89X@1236|Gammaproteobacteria,1XWV8@135623|Vibrionales 135623|Vibrionales T response regulator - - - - - - - - - - - - Response_reg k141_36899_18 1116375.VEJY3_06010 0.0 1100.0 COG0664@1|root,COG0784@1|root,COG4191@1|root,COG0664@2|Bacteria,COG0784@2|Bacteria,COG4191@2|Bacteria,1R97I@1224|Proteobacteria,1RNJ8@1236|Gammaproteobacteria,1XSZK@135623|Vibrionales 135623|Vibrionales T COG0642 Signal transduction histidine kinase VP1245 - - - - - - - - - - - HATPase_c,HisKA,Response_reg,cNMP_binding k141_36899_19 674977.VMC_40460 2.45e-260 718.0 COG5339@1|root,COG5339@2|Bacteria,1N902@1224|Proteobacteria,1SDR2@1236|Gammaproteobacteria,1XSXF@135623|Vibrionales 135623|Vibrionales S Bacterial protein of unknown function (DUF945) - - - - - - - - - - - - DUF945 k141_36899_20 223926.28806235 4.25e-251 690.0 COG1932@1|root,COG1932@2|Bacteria,1MUB5@1224|Proteobacteria,1RMKU@1236|Gammaproteobacteria,1XSV4@135623|Vibrionales 135623|Vibrionales E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine serC GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 M00020,M00124 R04173,R05085 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_5 k141_36899_21 270374.MELB17_05924 4.49e-19 87.8 29456@1|root,2ZRJR@2|Bacteria,1PARV@1224|Proteobacteria,1SW8G@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_29778_1 218284.CCDN010000001_gene955 1.62e-40 134.0 2E555@1|root,32ZY3@2|Bacteria,1VEM4@1239|Firmicutes,4HNK4@91061|Bacilli,1ZI0F@1386|Bacillus 91061|Bacilli S stage III sporulation protein AC spoIIIAC - - ko:K06392 - - - - ko00000 - - - SpoIIIAC k141_1225_1 421052.F945_01628 1.12e-09 69.7 COG0584@1|root,COG0584@2|Bacteria,1NAYR@1224|Proteobacteria,1SG4P@1236|Gammaproteobacteria,3NK9T@468|Moraxellaceae 1236|Gammaproteobacteria C Glycerophosphoryl diester phosphodiesterase family - - - - - - - - - - - - DUF1080,GDPD k141_1225_2 1274524.BSONL12_13201 4.57e-195 568.0 COG4926@1|root,COG4926@2|Bacteria,1UUXK@1239|Firmicutes,4I28Q@91061|Bacilli,1ZG8N@1386|Bacillus 91061|Bacilli L Prophage endopeptidase tail - - - - - - - - - - - - Prophage_tail k141_26232_2 1279017.AQYJ01000022_gene2641 9.19e-38 128.0 2EHQ3@1|root,33BFV@2|Bacteria,1NHBP@1224|Proteobacteria,1SDE8@1236|Gammaproteobacteria,46CFB@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_26232_4 1453501.JELR01000001_gene3204 8.98e-65 200.0 COG3584@1|root,COG3584@2|Bacteria,1MZPJ@1224|Proteobacteria,1SBH0@1236|Gammaproteobacteria,46BSK@72275|Alteromonadaceae 1236|Gammaproteobacteria S 3D domain protein DR0488 - - - - - - - - - - - - k141_26232_7 1042377.AFPJ01000011_gene421 9.59e-73 228.0 COG1683@1|root,COG3272@1|root,COG1683@2|Bacteria,COG3272@2|Bacteria,1MXYZ@1224|Proteobacteria,1RNMF@1236|Gammaproteobacteria,464ZQ@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF1722) ybgA - - - - - - - - - - - DUF1722,DUF523 k141_22680_1 1454004.AW11_03381 5.96e-62 210.0 COG3386@1|root,COG3386@2|Bacteria,1QW76@1224|Proteobacteria 1224|Proteobacteria G PFAM SMP-30 Gluconolaconase - - - - - - - - - - - - - k141_10750_1 1042377.AFPJ01000007_gene1921 4.21e-136 404.0 COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,1RMS8@1236|Gammaproteobacteria,4657M@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) slt GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009274,GO:0016740,GO:0016757,GO:0030203,GO:0030288,GO:0030312,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - ko:K08309 - - - - ko00000,ko01000,ko01011 - GH23 iETEC_1333.ETEC_4747,iPC815.YPO0452 SLT,SLT_L k141_7181_2 1294265.JCM21738_146 4.1e-78 240.0 COG0413@1|root,COG0413@2|Bacteria,1TPZA@1239|Firmicutes,4H9S8@91061|Bacilli,1ZAWV@1386|Bacillus 91061|Bacilli H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate panB - 2.1.2.11 ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R01226 RC00022,RC00200 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU22430 Pantoate_transf k141_3649_1 1294265.JCM21738_2432 1.13e-115 333.0 COG0705@1|root,COG0705@2|Bacteria,1UYXN@1239|Firmicutes,4HCIU@91061|Bacilli,1ZRQJ@1386|Bacillus 91061|Bacilli S membrane protein (homolog of Drosophila rhomboid) ydcA - 3.4.21.105 ko:K19225 - - - - ko00000,ko01000,ko01002 - - - Rhomboid k141_6020_1 558169.AGAV01000014_gene1722 5.66e-10 57.8 COG0218@1|root,COG0218@2|Bacteria,1TSPW@1239|Firmicutes,4HBXZ@91061|Bacilli 91061|Bacilli D Necessary for normal cell division and for the maintenance of normal septation engB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K03978 - - - - ko00000,ko03036 - - - MMR_HSR1 k141_6020_2 240302.BN982_00452 1.12e-90 287.0 COG0466@1|root,COG0466@2|Bacteria,1TNYG@1239|Firmicutes,4HAZK@91061|Bacilli,3NEA2@45667|Halobacillus 91061|Bacilli O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner lon GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.4.21.53 ko:K01338 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - AAA,LON_substr_bdg,Lon_C k141_33358_1 1279017.AQYJ01000023_gene3093 5.02e-72 236.0 COG1228@1|root,COG1228@2|Bacteria,1MY4V@1224|Proteobacteria,1RZRK@1236|Gammaproteobacteria,46606@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Amidohydrolase family - - - - - - - - - - - - Amidohydro_1 k141_29779_1 1121085.AUCI01000042_gene3055 1.87e-68 212.0 COG0288@1|root,COG0288@2|Bacteria,1V1EC@1239|Firmicutes,4HFQA@91061|Bacilli,1ZB5T@1386|Bacillus 91061|Bacilli P Reversible hydration of carbon dioxide yvdA - 4.2.1.1 ko:K01673 ko00910,map00910 - R00132,R10092 RC02807 ko00000,ko00001,ko01000 - - - Pro_CA k141_30994_2 218284.CCDN010000005_gene3447 6.06e-91 267.0 COG2111@1|root,COG2111@2|Bacteria,1V3VF@1239|Firmicutes,4HHAN@91061|Bacilli,1ZHC0@1386|Bacillus 91061|Bacilli P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali mrpB - - ko:K05566 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - MnhB k141_22681_1 1280001.BAOA01000066_gene2725 7e-148 422.0 COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,1RMDH@1236|Gammaproteobacteria,1XTP5@135623|Vibrionales 135623|Vibrionales H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III hemE GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019353,GO:0019438,GO:0019752,GO:0033013,GO:0033014,GO:0033526,GO:0034641,GO:0042168,GO:0042440,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 4.1.1.37 ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03197,R04972 RC00872 ko00000,ko00001,ko00002,ko01000 - - - URO-D k141_13168_2 218284.CCDN010000006_gene3589 0.0 881.0 COG1027@1|root,COG1027@2|Bacteria,1TP3U@1239|Firmicutes,4HFM9@91061|Bacilli,1ZB5F@1386|Bacillus 91061|Bacilli E Aspartate ammonia-lyase aspA - 4.3.1.1 ko:K01744 ko00250,ko01100,map00250,map01100 - R00490 RC00316,RC02799 ko00000,ko00001,ko01000 - - - FumaraseC_C,Lyase_1 k141_7182_1 697281.Mahau_0104 1.41e-47 169.0 COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247V6@186801|Clostridia,42G18@68295|Thermoanaerobacterales 186801|Clostridia L Belongs to the 'phage' integrase family - - - - - - - - - - - - Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase k141_2475_1 1453501.JELR01000005_gene1768 2.1e-47 158.0 COG2885@1|root,COG2885@2|Bacteria,1RIG3@1224|Proteobacteria,1S5WW@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Belongs to the ompA family - - - - - - - - - - - - DUF4398,OmpA k141_2475_3 377629.TERTU_1038 2.62e-05 47.4 COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,1RMXX@1236|Gammaproteobacteria,2PMGK@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria S MviN-like protein murJ GO:0000270,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0006869,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0010876,GO:0015647,GO:0015648,GO:0015835,GO:0015836,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0030203,GO:0031224,GO:0031226,GO:0033036,GO:0034203,GO:0034204,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0046836,GO:0051179,GO:0051234,GO:0055085,GO:0061024,GO:0065007,GO:0065008,GO:0070589,GO:0071554,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0071944,GO:0097035,GO:1901135,GO:1901137,GO:1901264,GO:1901505,GO:1901564,GO:1901566,GO:1901576 - ko:K03980 - - - - ko00000,ko01011,ko02000 2.A.66.4 - iECO103_1326.ECO103_1114 MVIN k141_6021_1 585423.KR49_03395 6.26e-62 202.0 COG2370@1|root,COG2370@2|Bacteria,1G65K@1117|Cyanobacteria,1GZTA@1129|Synechococcus 1117|Cyanobacteria O HupE / UreJ protein - - - - - - - - - - - - HupE_UreJ_2 k141_23827_2 218284.CCDN010000001_gene12 2.54e-60 193.0 COG0164@1|root,COG0164@2|Bacteria,1V1D6@1239|Firmicutes,4HB7M@91061|Bacilli,1ZB7H@1386|Bacillus 91061|Bacilli L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03470 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_HII k141_34554_1 218284.CCDN010000006_gene3575 6.61e-60 202.0 COG4264@1|root,COG4264@2|Bacteria,1V0HB@1239|Firmicutes,4HAUQ@91061|Bacilli,1ZCKN@1386|Bacillus 91061|Bacilli Q Siderophore biosynthesis protein asbA - - - - - - - - - - - FhuF,IucA_IucC k141_14349_1 218284.CCDN010000001_gene1234 2.05e-74 230.0 COG0523@1|root,COG0523@2|Bacteria,1TPCG@1239|Firmicutes,4HFQ5@91061|Bacilli,1ZBXA@1386|Bacillus 91061|Bacilli S cobalamin synthesis protein P47K - - - - - - - - - - - - CobW_C,cobW k141_4839_1 218284.CCDN010000006_gene3588 2.55e-71 227.0 COG1396@1|root,COG1396@2|Bacteria 2|Bacteria K sequence-specific DNA binding - - - ko:K18830 - - - - ko00000,ko02048,ko03000 - - - HTH_19,HTH_3 k141_25013_1 574376.BAMA_19990 3.18e-26 103.0 COG3393@1|root,COG3393@2|Bacteria,1UFJG@1239|Firmicutes,4HGNR@91061|Bacilli,1ZEBH@1386|Bacillus 91061|Bacilli S GNAT acetyltransferase - - - ko:K06976 - - - - ko00000 - - - Acetyltransf_10,Acetyltransf_9,GNAT_acetyltran k141_25013_2 866895.HBHAL_3954 8.14e-37 127.0 COG2329@1|root,COG2329@2|Bacteria,1VCVN@1239|Firmicutes,4HKEU@91061|Bacilli,3NF6S@45667|Halobacillus 91061|Bacilli S Antibiotic biosynthesis monooxygenase - - 1.14.99.57 ko:K21481 - - - - ko00000,ko01000 - - - ABM k141_26234_1 218284.CCDN010000001_gene791 8.28e-131 375.0 COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,4HAB1@91061|Bacilli,1ZBQ5@1386|Bacillus 91061|Bacilli P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system pstBA - 3.6.3.27 ko:K02036 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 - - ABC_tran k141_15547_1 1323663.AROI01000024_gene1548 8.29e-65 213.0 COG0277@1|root,COG0277@2|Bacteria,1MUKV@1224|Proteobacteria,1RSF4@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Fad linked oxidase - - - - - - - - - - - - FAD_binding_4 k141_19082_1 1279017.AQYJ01000029_gene3774 1.19e-37 126.0 COG0333@1|root,COG0333@2|Bacteria,1N6RF@1224|Proteobacteria,1SC9G@1236|Gammaproteobacteria,468BN@72275|Alteromonadaceae 1236|Gammaproteobacteria J Belongs to the bacterial ribosomal protein bL32 family rpmF GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - ko:K02911 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_L32p k141_19082_2 1279017.AQYJ01000029_gene3773 8.78e-77 233.0 COG1399@1|root,COG1399@2|Bacteria,1PGKW@1224|Proteobacteria,1RRK3@1236|Gammaproteobacteria,46873@72275|Alteromonadaceae 1236|Gammaproteobacteria S metal-binding, possibly nucleic acid-binding protein yceD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K07040 - - - - ko00000 - - - DUF177 k141_36900_1 218284.CCDN010000001_gene386 1.1e-86 270.0 COG0778@1|root,COG0778@2|Bacteria,1UWU9@1239|Firmicutes,4H9ZQ@91061|Bacilli,1ZDAF@1386|Bacillus 91061|Bacilli C Nitroreductase family - - - - - - - - - - - - Nitroreductase k141_16693_1 1453501.JELR01000002_gene511 3.09e-102 309.0 COG2133@1|root,COG2133@2|Bacteria,1MVK5@1224|Proteobacteria,1RPE8@1236|Gammaproteobacteria,4665U@72275|Alteromonadaceae 1236|Gammaproteobacteria G COG2133 Glucose sorbosone dehydrogenases - - - - - - - - - - - - GSDH k141_14350_1 1294265.JCM21738_530 5.63e-74 224.0 2EA57@1|root,334A4@2|Bacteria,1VHEA@1239|Firmicutes,4HQZU@91061|Bacilli,1ZIXN@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_34555_1 218284.CCDN010000001_gene1553 5.72e-79 236.0 COG4326@1|root,COG4326@2|Bacteria,1VHE9@1239|Firmicutes,4HP75@91061|Bacilli,1ZJ9B@1386|Bacillus 91061|Bacilli S SpoOM protein - - - ko:K06377 - - - - ko00000 - - - Spo0M k141_94_1 218284.CCDN010000005_gene3346 1.39e-49 167.0 COG2199@1|root,COG3706@2|Bacteria,1V2QN@1239|Firmicutes,4HFY9@91061|Bacilli,1ZCMZ@1386|Bacillus 91061|Bacilli T diguanylate cyclase - - - - - - - - - - - - 5TM-5TMR_LYT,GGDEF,PAS_3 k141_17929_1 10753.B7SSN3_BPNF 3.43e-13 76.3 4QCGF@10239|Viruses,4QWW8@35237|dsDNA viruses no RNA stage 10239|Viruses S Peptidase_G2, IMC autoproteolytic cleavage domain - - - - - - - - - - - - - k141_20263_1 1123237.Salmuc_05184 6.47e-82 246.0 COG1959@1|root,COG1959@2|Bacteria,1N05H@1224|Proteobacteria,2UBZM@28211|Alphaproteobacteria 28211|Alphaproteobacteria K transcriptional regulator - - - ko:K13771 ko05132,map05132 - - - ko00000,ko00001,ko03000 - - - Rrf2 k141_13170_1 1294265.JCM21738_3508 6.78e-36 132.0 COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,4HA70@91061|Bacilli,1ZCE3@1386|Bacillus 91061|Bacilli F Belongs to the GARS family purD - 6.3.4.13 ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144 RC00090,RC00166 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS05245,iYO844.BSU06530 GARS_A,GARS_C,GARS_N k141_13170_2 997296.PB1_05587 8.38e-74 235.0 COG0138@1|root,COG0138@2|Bacteria,1TPQ5@1239|Firmicutes,4H9YY@91061|Bacilli,1ZD5E@1386|Bacillus 91061|Bacilli F Bifunctional purine biosynthesis protein PurH purH - 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 - - - AICARFT_IMPCHas,MGS k141_36901_1 218284.CCDN010000001_gene1357 1.15e-116 353.0 COG0514@1|root,COG0514@2|Bacteria,1TPN5@1239|Firmicutes,4H9QP@91061|Bacilli,1ZC4U@1386|Bacillus 91061|Bacilli L DNA helicase recQ GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009378,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.6.4.12 ko:K03654 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind k141_17930_1 1347086.CCBA010000027_gene3387 5.73e-100 290.0 COG0454@1|root,COG0454@2|Bacteria,1V7G7@1239|Firmicutes,4HJVQ@91061|Bacilli,1ZCIH@1386|Bacillus 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_10,Acetyltransf_7 k141_14351_1 1294265.JCM21738_4077 2.36e-143 423.0 COG1948@1|root,COG4886@1|root,COG4880@2|Bacteria,COG4886@2|Bacteria,1TQK0@1239|Firmicutes,4H9YF@91061|Bacilli,1ZDVB@1386|Bacillus 91061|Bacilli L Beta propeller domain - - - - - - - - - - - - Beta_propel,Big_5,Cu_amine_oxidN1 k141_10751_1 1042377.AFPJ01000052_gene1526 3.27e-85 273.0 COG5001@1|root,COG5001@2|Bacteria,1NQIF@1224|Proteobacteria,1T3FC@1236|Gammaproteobacteria,46CJ0@72275|Alteromonadaceae 1236|Gammaproteobacteria T diguanylate cyclase - - 2.7.7.65 ko:K20956,ko:K21023 ko02025,ko05111,map02025,map05111 - - - ko00000,ko00001,ko01000 - - - CHASE,EAL,GAF_2,GGDEF,PAS_4,PAS_9 k141_35739_1 218284.CCDN010000004_gene3136 2.24e-71 218.0 COG1559@1|root,COG1559@2|Bacteria,1TX6D@1239|Firmicutes,4IKF7@91061|Bacilli,1ZGTZ@1386|Bacillus 91061|Bacilli S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation - - - - - - - - - - - - - k141_19083_1 1499680.CCFE01000033_gene3933 1.4e-102 310.0 COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,4HAB3@91061|Bacilli,1ZAPP@1386|Bacillus 91061|Bacilli JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity cshA GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 3.6.4.13 ko:K05592 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,Helicase_C k141_2476_1 1333507.AUTQ01000260_gene3660 2.45e-49 163.0 COG2303@1|root,COG2303@2|Bacteria,1RH5U@1224|Proteobacteria,1S60X@1236|Gammaproteobacteria,2Q2WF@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria E Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - - - - - - - - - - - k141_2476_2 1384056.N787_06680 1.81e-42 146.0 2FI27@1|root,349V2@2|Bacteria,1P2SK@1224|Proteobacteria,1ST3D@1236|Gammaproteobacteria,1XBSQ@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - k141_95_1 574375.BAGA_04445 2.59e-90 288.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,4H9S7@91061|Bacilli,1ZB6Y@1386|Bacillus 91061|Bacilli L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A k141_17931_1 580327.Tthe_1924 6.78e-38 141.0 COG1621@1|root,COG1621@2|Bacteria,1TPAE@1239|Firmicutes,247UU@186801|Clostridia,42I4K@68295|Thermoanaerobacterales 186801|Clostridia G SMART glycoside hydrolase, family 32 - - 3.2.1.26 ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00801,R00802,R02410,R03635,R03921,R06088 RC00028,RC00077 ko00000,ko00001,ko01000 - GH32 - Glyco_hydro_32C,Glyco_hydro_32N k141_36902_2 1384049.CD29_18310 2.31e-11 63.2 29QXP@1|root,30BYF@2|Bacteria,1U8VS@1239|Firmicutes,4IIU7@91061|Bacilli,3IZHK@400634|Lysinibacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_21490_1 218284.CCDN010000006_gene3660 1.06e-122 360.0 COG0111@1|root,COG0111@2|Bacteria,1V410@1239|Firmicutes,4H9PH@91061|Bacilli,1ZCBB@1386|Bacillus 91061|Bacilli EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family serA - 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C,ACT_4 k141_34556_1 1033734.CAET01000042_gene426 1.91e-53 181.0 COG0860@1|root,COG3409@1|root,COG0860@2|Bacteria,COG3409@2|Bacteria,1V3EN@1239|Firmicutes,4HEBK@91061|Bacilli,1ZI9F@1386|Bacillus 91061|Bacilli M N-acetylmuramoyl-L-alanine amidase - - 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - Amidase_3 k141_34556_2 10753.B7SSN7_BPNF 1.74e-87 266.0 4QB67@10239|Viruses,4QVZK@35237|dsDNA viruses no RNA stage,4QU61@28883|Caudovirales,4QP0F@10744|Podoviridae 10744|Podoviridae S Podovirus DNA encapsidation protein (Gp16) - - - - - - - - - - - - - k141_5069_1 1033734.CAET01000013_gene1777 9.31e-176 498.0 COG1914@1|root,COG1914@2|Bacteria,1V04N@1239|Firmicutes,4HBF6@91061|Bacilli,1ZF5E@1386|Bacillus 91061|Bacilli P Natural resistance-associated macrophage protein mntH_2 - - - - - - - - - - - Nramp k141_18219_1 1210908.HSB1_10010 3.87e-46 153.0 COG2514@1|root,arCOG06106@2157|Archaea,2Y43R@28890|Euryarchaeota,23ZV2@183963|Halobacteria 183963|Halobacteria S Glyoxalase-like domain - - - - - - - - - - - - Glyoxalase k141_28888_1 1219076.N646_3112 2.15e-75 227.0 COG1607@1|root,COG1607@2|Bacteria,1RAEQ@1224|Proteobacteria,1S313@1236|Gammaproteobacteria,1XTW2@135623|Vibrionales 135623|Vibrionales I Acyl-CoA hydrolase - - - - - - - - - - - - 4HBT k141_28888_2 1280001.BAOA01000027_gene4871 3.24e-178 500.0 COG0697@1|root,COG0697@2|Bacteria,1R9B0@1224|Proteobacteria,1RZ6Q@1236|Gammaproteobacteria,1Y2CK@135623|Vibrionales 135623|Vibrionales EG EamA-like transporter family - - - - - - - - - - - - EamA k141_28888_3 674977.VMC_19310 1.22e-53 169.0 COG2926@1|root,COG2926@2|Bacteria,1RH0U@1224|Proteobacteria,1S6XT@1236|Gammaproteobacteria,1XXYA@135623|Vibrionales 135623|Vibrionales S Belongs to the UPF0265 family - - - ko:K09802 - - - - ko00000 - - - DUF496 k141_28888_4 1116375.VEJY3_17516 8.38e-32 112.0 2AWX6@1|root,31NUS@2|Bacteria,1QKIF@1224|Proteobacteria,1TINP@1236|Gammaproteobacteria,1XZDR@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_28888_5 1116375.VEJY3_17521 2.6e-124 357.0 COG3132@1|root,COG3132@2|Bacteria,1RA13@1224|Proteobacteria,1RQUQ@1236|Gammaproteobacteria,1XUQY@135623|Vibrionales 135623|Vibrionales S Belongs to the UPF0502 family yceH - - ko:K09915 - - - - ko00000 - - - DUF480 k141_28888_6 1116375.VEJY3_17526 3.09e-49 158.0 COG2827@1|root,COG2827@2|Bacteria,1N6PA@1224|Proteobacteria,1SCBH@1236|Gammaproteobacteria,1XYY3@135623|Vibrionales 135623|Vibrionales L endonuclease containing a URI domain yhbQ - - ko:K07461 - - - - ko00000 - - - GIY-YIG k141_28888_7 1116375.VEJY3_17531 1.57e-239 661.0 COG1879@1|root,COG1879@2|Bacteria,1NKCW@1224|Proteobacteria,1RT5N@1236|Gammaproteobacteria,1XV03@135623|Vibrionales 135623|Vibrionales G COG1879 ABC-type sugar transport system, periplasmic component luxP GO:0006355,GO:0006810,GO:0008150,GO:0008643,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051179,GO:0051234,GO:0051252,GO:0060255,GO:0065007,GO:0071702,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K10910 ko02020,ko02024,ko05111,map02020,map02024,map05111 - - - ko00000,ko00001 - - - Peripla_BP_4 k141_28888_8 1116375.VEJY3_17536 0.0 1469.0 COG0642@1|root,COG2205@2|Bacteria,1N96D@1224|Proteobacteria,1T1YZ@1236|Gammaproteobacteria,1Y339@135623|Vibrionales 135623|Vibrionales T COG0642 Signal transduction histidine kinase luxQ - 2.7.13.3 ko:K10909 ko02020,ko02024,ko05111,map02020,map02024,map05111 M00513 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,LuxQ-periplasm,Response_reg k141_28888_9 1116375.VEJY3_17541 6.33e-85 252.0 COG1846@1|root,COG1846@2|Bacteria,1N78T@1224|Proteobacteria,1S26B@1236|Gammaproteobacteria,1XX2C@135623|Vibrionales 135623|Vibrionales K helix_turn_helix multiple antibiotic resistance protein - - - ko:K06075 - - - - ko00000,ko03000 - - - MarR k141_28888_10 1116375.VEJY3_17546 5.98e-226 625.0 COG1566@1|root,COG1566@2|Bacteria,1MU7I@1224|Proteobacteria,1RPV2@1236|Gammaproteobacteria,1XUFT@135623|Vibrionales 135623|Vibrionales V Secretion protein - - - - - - - - - - - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 k141_28888_11 1116375.VEJY3_17551 3.64e-228 630.0 28HJP@1|root,2Z7UT@2|Bacteria,1MWM4@1224|Proteobacteria,1RQNG@1236|Gammaproteobacteria,1XUX1@135623|Vibrionales 135623|Vibrionales S of the major facilitator superfamily - - - - - - - - - - - - DUF2955,FUSC_2 k141_28888_12 1116375.VEJY3_17561 1.9e-177 499.0 COG0697@1|root,COG0697@2|Bacteria,1RI87@1224|Proteobacteria,1S4HT@1236|Gammaproteobacteria,1XU25@135623|Vibrionales 135623|Vibrionales EG of the drug metabolite transporter (DMT) superfamily VPA1215 - - - - - - - - - - - EamA k141_28888_13 1219076.N646_3899 2.61e-93 273.0 COG1522@1|root,COG1522@2|Bacteria,1RISV@1224|Proteobacteria,1S78M@1236|Gammaproteobacteria,1XX1G@135623|Vibrionales 135623|Vibrionales K helix_turn_helix ASNC type - - - ko:K03719 - - - - ko00000,ko03000,ko03036 - - - AsnC_trans_reg,HTH_24,HTH_AsnC-type k141_28888_14 1116375.VEJY3_17571 3.78e-73 225.0 2AWBD@1|root,31N73@2|Bacteria,1QJYF@1224|Proteobacteria,1TI0P@1236|Gammaproteobacteria,1XY3G@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_28888_15 1116375.VEJY3_17576 1.32e-116 338.0 2EVF3@1|root,33NVI@2|Bacteria,1NPYI@1224|Proteobacteria,1SV5C@1236|Gammaproteobacteria,1XW0P@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - SH3_3 k141_28888_16 223926.28809578 1.18e-63 199.0 2AW76@1|root,31N3N@2|Bacteria,1QJV7@1224|Proteobacteria,1THWT@1236|Gammaproteobacteria,1XXRJ@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_31255_1 218284.CCDN010000001_gene1330 4.38e-117 361.0 COG0567@1|root,COG0567@2|Bacteria,1TRDW@1239|Firmicutes,4HAUI@91061|Bacilli,1ZAX3@1386|Bacillus 91061|Bacilli C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) odhA GO:0003674,GO:0003824,GO:0004591,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016624,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045333,GO:0055114,GO:0071704,GO:0072350,GO:1902494,GO:1990204,GO:1990234 1.2.4.2 ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R00621,R01933,R01940,R03316,R08549 RC00004,RC00027,RC00627,RC02743,RC02833,RC02883 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr k141_27581_1 555779.Dthio_PD3225 5.71e-56 189.0 COG1456@1|root,COG1456@2|Bacteria,1R4RE@1224|Proteobacteria,42M89@68525|delta/epsilon subdivisions,2WJVQ@28221|Deltaproteobacteria 28221|Deltaproteobacteria C CO dehydrogenase acetyl-CoA synthase delta subunit - - 2.1.1.245 ko:K00197 ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200 M00357,M00377,M00422 R09096,R10219,R10243 RC00004,RC00113,RC02977 ko00000,ko00001,ko00002,ko01000 - - - CdhD,FeS k141_34789_1 866895.HBHAL_1871 6.21e-125 361.0 COG1284@1|root,COG1284@2|Bacteria,1TR9J@1239|Firmicutes,4H9N6@91061|Bacilli,3NDH2@45667|Halobacillus 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2179) yvjA - - - - - - - - - - - DUF2179,YitT_membrane k141_5070_2 406124.ACPC01000015_gene2099 1.68e-16 77.8 COG3508@1|root,COG3508@2|Bacteria,1UYZ0@1239|Firmicutes,4HCCC@91061|Bacilli,1ZC6Q@1386|Bacillus 91061|Bacilli Q homogentisate 12-dioxygenase hmgA - 1.13.11.5 ko:K00451 ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120 M00044 R02519 RC00737 ko00000,ko00001,ko00002,ko01000 - - - HgmA k141_13462_1 1453501.JELR01000002_gene1252 1.46e-15 75.1 COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,1RPZ7@1236|Gammaproteobacteria,464GR@72275|Alteromonadaceae 1236|Gammaproteobacteria L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA priA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006276,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0010332,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042221,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0046677,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - ko:K04066 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,ResIII k141_13462_2 1453501.JELR01000002_gene1253 4.99e-74 226.0 COG3087@1|root,COG3087@2|Bacteria,1MYFG@1224|Proteobacteria,1S9Y3@1236|Gammaproteobacteria,467S5@72275|Alteromonadaceae 1236|Gammaproteobacteria D COG3087 Cell division protein - - - ko:K03591 - - - - ko00000,ko03036 - - - SPOR k141_19320_1 315749.Bcer98_1870 3.24e-190 538.0 COG1167@1|root,COG1167@2|Bacteria,1TPS5@1239|Firmicutes,4HB1C@91061|Bacilli,1ZASA@1386|Bacillus 91061|Bacilli K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs - - - ko:K18907 - M00700,M00702 - - ko00000,ko00002,ko01504,ko03000 - - - Aminotran_1_2,GntR k141_24072_1 218284.CCDN010000002_gene2867 2.29e-145 428.0 COG1858@1|root,COG3391@1|root,COG1858@2|Bacteria,COG3391@2|Bacteria,1V255@1239|Firmicutes,4HEF2@91061|Bacilli,1ZPVH@1386|Bacillus 91061|Bacilli P Lactonase, 7-bladed beta-propeller - - - - - - - - - - - - Cytochrom_D1,DHOR,Lactonase k141_2725_1 218284.CCDN010000007_gene4031 2.12e-78 249.0 COG4715@1|root,COG4715@2|Bacteria,1TSUG@1239|Firmicutes,4HGS4@91061|Bacilli,1ZC8Y@1386|Bacillus 91061|Bacilli S Zinc finger, swim domain protein - - - - - - - - - - - - SWIM k141_18220_1 1294265.JCM21738_4845 4.84e-32 112.0 COG4853@1|root,COG4853@2|Bacteria 2|Bacteria S YycH protein yycI - - - - - - - - - - - YycI k141_12310_1 1196031.ALEG01000029_gene3661 6.07e-122 357.0 COG0477@1|root,COG2814@2|Bacteria,1UXXX@1239|Firmicutes,4HC83@91061|Bacilli,1ZBD6@1386|Bacillus 91061|Bacilli EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1,Sugar_tr k141_20462_1 1123053.AUDG01000018_gene3018 6e-117 346.0 COG0642@1|root,COG0642@2|Bacteria,1R54C@1224|Proteobacteria,1RNTM@1236|Gammaproteobacteria,1X29B@135613|Chromatiales 135613|Chromatiales T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HisKA k141_34790_1 218284.CCDN010000002_gene2146 1.55e-63 205.0 COG0026@1|root,COG0026@2|Bacteria,1TTDR@1239|Firmicutes,4HDHY@91061|Bacilli 91061|Bacilli F Carboxylate--amine ligase - - - - - - - - - - - - ATP-grasp_4 k141_34790_2 218284.CCDN010000002_gene2147 1.44e-25 104.0 2C593@1|root,2Z84R@2|Bacteria,1U546@1239|Firmicutes,4HEHB@91061|Bacilli,1ZMHC@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_37100_1 240302.BN982_02298 2.7e-19 80.1 2DGZH@1|root,2ZXV8@2|Bacteria,1W48K@1239|Firmicutes,4I1II@91061|Bacilli,3NG73@45667|Halobacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_10997_1 1042377.AFPJ01000043_gene940 8.1e-134 384.0 COG0745@1|root,COG0745@2|Bacteria,1RA00@1224|Proteobacteria,1S23N@1236|Gammaproteobacteria,466JJ@72275|Alteromonadaceae 1236|Gammaproteobacteria KT Transcriptional regulatory protein, C terminal - - - - - - - - - - - - Response_reg,Trans_reg_C k141_10997_2 1042377.AFPJ01000043_gene939 5.05e-168 484.0 COG0642@1|root,COG0642@2|Bacteria,1R54G@1224|Proteobacteria,1RWXF@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Histidine kinase colS - - - - - - - - - - - HATPase_c,HisKA k141_10997_3 1042377.AFPJ01000043_gene938 6.01e-156 449.0 COG0693@1|root,COG0693@2|Bacteria,1MVTT@1224|Proteobacteria,1RPVK@1236|Gammaproteobacteria,465PW@72275|Alteromonadaceae 1236|Gammaproteobacteria S DJ-1/PfpI family - - - - - - - - - - - - DJ-1_PfpI k141_10997_4 1117314.PCIT_07337 2.87e-101 306.0 COG1073@1|root,COG1073@2|Bacteria,1RBDQ@1224|Proteobacteria,1S2TK@1236|Gammaproteobacteria,2Q4HV@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria S Acetyl xylan esterase (AXE1) - - - - - - - - - - - - AXE1 k141_10997_5 1453501.JELR01000002_gene801 5.24e-81 243.0 COG0801@1|root,COG0801@2|Bacteria,1RHNN@1224|Proteobacteria,1S62M@1236|Gammaproteobacteria,46782@72275|Alteromonadaceae 1236|Gammaproteobacteria H COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase folK2 - 2.7.6.3 ko:K00950 ko00790,ko01100,map00790,map01100 M00126,M00841 R03503 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - HPPK k141_10997_6 1279017.AQYJ01000020_gene1263 8.59e-74 222.0 COG1539@1|root,COG1539@2|Bacteria,1MZ8Z@1224|Proteobacteria,1S9B2@1236|Gammaproteobacteria,468QX@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin folB GO:0003674,GO:0003824,GO:0004150,GO:0005488,GO:0005515,GO:0016829,GO:0016830,GO:0016832,GO:0042802 1.13.11.81,4.1.2.25,5.1.99.8 ko:K01633 ko00790,ko01100,map00790,map01100 M00126,M00840 R03504,R11037,R11073 RC00721,RC00943,RC01479,RC03333,RC03334 ko00000,ko00001,ko00002,ko01000 - - iECDH1ME8569_1439.ECDH1ME8569_2955,iECSE_1348.ECSE_3338,iPC815.YPO0648,iSBO_1134.SBO_2914,iSDY_1059.SDY_3241,iSFxv_1172.SFxv_3403,iUTI89_1310.UTI89_C3494,iYL1228.KPN_03462,ic_1306.c3808 FolB k141_9820_1 1294265.JCM21738_5267 7.12e-129 372.0 COG0454@1|root,COG0456@2|Bacteria,1V2UB@1239|Firmicutes,4HG0K@91061|Bacilli,1ZFBM@1386|Bacillus 91061|Bacilli K acetyltransferase - - - - - - - - - - - - Acetyltransf_1 k141_34791_1 713586.KB900536_gene1962 3.67e-138 408.0 COG2936@1|root,COG2936@2|Bacteria,1MVA8@1224|Proteobacteria,1RN7H@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Peptidase S15 cocE - - ko:K06978 - - - - ko00000 - - - PepX_C,Peptidase_S15 k141_2726_1 1095769.CAHF01000010_gene1120 3.45e-88 286.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,475RC@75682|Oxalobacteraceae 28216|Betaproteobacteria V MMPL family bepE_3 - - ko:K18307 ko02024,map02024 M00644 - - ko00000,ko00001,ko00002,ko02000 2.A.6.2.20,2.A.6.2.32 - - ACR_tran k141_13465_1 35841.BT1A1_1118 1.58e-32 122.0 COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,4HA4E@91061|Bacilli,1ZB72@1386|Bacillus 91061|Bacilli P Belongs to the ABC transporter superfamily - - - ko:K02031 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - ABC_tran,oligo_HPY k141_5071_1 1279017.AQYJ01000028_gene2411 4.92e-36 132.0 COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,1RMTM@1236|Gammaproteobacteria,4659J@72275|Alteromonadaceae 1236|Gammaproteobacteria F Belongs to the D-alanine--D-alanine ligase family ddl GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008716,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - iAF1260.b0381,iB21_1397.B21_00332,iBWG_1329.BWG_0265,iE2348C_1286.E2348C_0317,iEC042_1314.EC042_0413,iEC55989_1330.EC55989_0386,iECBD_1354.ECBD_3283,iECB_1328.ECB_00328,iECDH10B_1368.ECDH10B_0338,iECDH1ME8569_1439.ECDH1ME8569_0367,iECD_1391.ECD_00328,iECH74115_1262.ECH74115_0453,iECIAI1_1343.ECIAI1_0377,iECIAI39_1322.ECIAI39_0301,iECO103_1326.ECO103_0356,iECO111_1330.ECO111_0411,iECO26_1355.ECO26_0414,iECSE_1348.ECSE_0401,iECSP_1301.ECSP_0441,iECs_1301.ECs0431,iETEC_1333.ETEC_0434,iEcDH1_1363.EcDH1_3227,iEcE24377_1341.EcE24377A_0406,iEcHS_1320.EcHS_A0447,iEcSMS35_1347.EcSMS35_0410,iEcolC_1368.EcolC_3251,iJO1366.b0381,iJR904.b0381,iSF_1195.SF0232,iSFxv_1172.SFxv_0245,iS_1188.S0254,iUMNK88_1353.UMNK88_429,iY75_1357.Y75_RS01965,iZ_1308.Z0477 Dala_Dala_lig_C,Dala_Dala_lig_N k141_5071_2 1279017.AQYJ01000028_gene2412 1.55e-144 413.0 COG3770@1|root,COG3770@2|Bacteria,1MU9I@1224|Proteobacteria,1RMJK@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus mepA GO:0000270,GO:0003674,GO:0003824,GO:0004175,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016787,GO:0019538,GO:0030203,GO:0034645,GO:0042221,GO:0042493,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0050896,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 - ko:K07261 - - - - ko00000,ko01000,ko01002,ko01011 - - iAPECO1_1312.APECO1_4236,iE2348C_1286.E2348C_2468,iECABU_c1320.ECABU_c26610,iECED1_1282.ECED1_2792,iECIAI39_1322.ECIAI39_2477,iECOK1_1307.ECOK1_2610,iECS88_1305.ECS88_2476,iEcSMS35_1347.EcSMS35_2485,iLF82_1304.LF82_1316,iNRG857_1313.NRG857_11790,iUMN146_1321.UM146_05170,iUTI89_1310.UTI89_C2613,ic_1306.c2874 Peptidase_M74 k141_3969_1 218284.CCDN010000007_gene3952 4.33e-151 430.0 COG4294@1|root,COG4294@2|Bacteria,1TTCB@1239|Firmicutes,4H9PY@91061|Bacilli,1ZCJ7@1386|Bacillus 91061|Bacilli L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion uvsE - - ko:K13281 - - - - ko00000,ko01000 - - - UvdE k141_3969_2 218284.CCDN010000007_gene3951 3.12e-30 107.0 COG4317@1|root,COG4317@2|Bacteria 2|Bacteria S XapX domain protein - - - - - - - - - - - - DUF1427 k141_3969_3 218284.CCDN010000007_gene3950 3.01e-186 530.0 COG0018@1|root,COG0018@2|Bacteria,1TPEZ@1239|Firmicutes,4HAR3@91061|Bacilli,1ZBP1@1386|Bacillus 91061|Bacilli J Arginyl-tRNA synthetase argS GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d k141_20463_1 218284.CCDN010000001_gene1213 6.74e-95 295.0 COG0840@1|root,COG0840@2|Bacteria,1UV22@1239|Firmicutes,4IBKM@91061|Bacilli,1ZERB@1386|Bacillus 91061|Bacilli NT CHASE3 domain - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - CHASE3,MCPsignal k141_1463_2 1294265.JCM21738_3091 2.17e-52 167.0 29RSK@1|root,30CWD@2|Bacteria,1UAGK@1239|Firmicutes,4HWGA@91061|Bacilli,1ZHRB@1386|Bacillus 91061|Bacilli S YolD-like protein - - - - - - - - - - - - YolD k141_24074_1 1042377.AFPJ01000020_gene2077 1e-72 224.0 COG1189@1|root,COG1189@2|Bacteria,1MWP5@1224|Proteobacteria,1S28A@1236|Gammaproteobacteria,466PV@72275|Alteromonadaceae 1236|Gammaproteobacteria J FtsJ-like methyltransferase - - 2.1.1.226,2.1.1.227 ko:K06442 - - - - ko00000,ko01000,ko03009 - - - FtsJ,S4 k141_12311_1 1116375.VEJY3_11940 2.19e-106 319.0 COG2304@1|root,COG2304@2|Bacteria,1MVJ2@1224|Proteobacteria,1RMUF@1236|Gammaproteobacteria,1XSUT@135623|Vibrionales 135623|Vibrionales S von willebrand factor, type A - - - - - - - - - - - - - k141_19321_1 218284.CCDN010000001_gene1824 1.17e-166 488.0 COG0550@1|root,COG0551@1|root,COG0550@2|Bacteria,COG0551@2|Bacteria,1TPJD@1239|Firmicutes,4HAZV@91061|Bacilli,1ZBEG@1386|Bacillus 91061|Bacilli L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topB - 5.99.1.2 ko:K03169 - - - - ko00000,ko01000,ko03032 - - - Topoisom_bac,Toprim k141_34792_1 218284.CCDN010000001_gene1308 1.88e-44 158.0 COG0697@1|root,COG0697@2|Bacteria,1TP7K@1239|Firmicutes,4HAH1@91061|Bacilli,1ZBEF@1386|Bacillus 91061|Bacilli EG Spore germination protein gerAA_1 - - ko:K06295 - - - - ko00000 - - - GerA k141_34792_2 265729.GS18_0212990 3.66e-17 81.6 COG0531@1|root,COG0531@2|Bacteria,1V1FX@1239|Firmicutes,4HFZN@91061|Bacilli,1ZFS6@1386|Bacillus 91061|Bacilli E Spore germination protein gerKB - - - - - - - - - - - Spore_permease k141_15799_1 1449353.JQMQ01000005_gene5208 2.28e-70 225.0 COG3285@1|root,COG3285@2|Bacteria,2GM0A@201174|Actinobacteria,2NFW0@228398|Streptacidiphilus 201174|Actinobacteria L DNA primase, small subunit - - 6.5.1.1 ko:K01971 ko03450,map03450 - R00381 RC00005 ko00000,ko00001,ko01000,ko03400 - - - - k141_8681_1 218284.CCDN010000001_gene589 3.86e-70 221.0 COG0457@1|root,COG0457@2|Bacteria,1V7T7@1239|Firmicutes,4HKAH@91061|Bacilli,1ZS6N@1386|Bacillus 91061|Bacilli H Tetratricopeptide repeat ysoA - - - - - - - - - - - TPR_19 k141_28897_1 42565.FP66_13330 1.06e-124 358.0 COG1120@1|root,COG1120@2|Bacteria,1MVKU@1224|Proteobacteria,1RN86@1236|Gammaproteobacteria,1XPFP@135619|Oceanospirillales 135619|Oceanospirillales HP ATPases associated with a variety of cellular activities - - 3.6.3.34 ko:K02013 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 - - ABC_tran k141_28897_2 290398.Csal_3092 4.84e-48 161.0 COG0697@1|root,COG0697@2|Bacteria,1MZXM@1224|Proteobacteria 1224|Proteobacteria EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - ko:K15270 - - - - ko00000,ko02000 2.A.7.3.7 - - EamA k141_22981_1 1042377.AFPJ01000045_gene2588 9.19e-63 197.0 COG3030@1|root,COG3030@2|Bacteria,1MZJJ@1224|Proteobacteria,1S8XU@1236|Gammaproteobacteria,467SJ@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein affecting phage T7 exclusion by the F plasmid fxsA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016021,GO:0031224,GO:0044425,GO:0044464,GO:0071944 - ko:K07113 - - - - ko00000 - - - FxsA k141_22981_2 1279017.AQYJ01000023_gene3260 2.81e-197 555.0 COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,1RNID@1236|Gammaproteobacteria,46CEQ@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG2230 Cyclopropane fatty acid synthase and related methyltransferases cfa - 2.1.1.79 ko:K00574 - - - - ko00000,ko01000 - - - CMAS k141_13493_1 745411.B3C1_14545 1.72e-54 186.0 COG0624@1|root,COG0624@2|Bacteria,1MWJS@1224|Proteobacteria,1RZXV@1236|Gammaproteobacteria,1J4HK@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases - - - ko:K13049 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20,Peptidase_M28 k141_13493_2 1565129.JSFF01000001_gene1091 1.61e-26 98.2 2EA6R@1|root,334BH@2|Bacteria,1N9KD@1224|Proteobacteria,1SE14@1236|Gammaproteobacteria,2QD1C@267890|Shewanellaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF3185) - - - - - - - - - - - - DUF3185 k141_26678_1 198467.NP92_08970 1.22e-14 68.6 COG2201@1|root,COG2201@2|Bacteria,1V71X@1239|Firmicutes,4HITX@91061|Bacilli,21VRB@150247|Anoxybacillus 91061|Bacilli NT cheY-homologous receiver domain yneI - - ko:K03413 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - Response_reg k141_26678_2 1294265.JCM21738_1147 8.2e-121 347.0 COG0785@1|root,COG0785@2|Bacteria,1TQH1@1239|Firmicutes,4H9UJ@91061|Bacilli,1ZBPX@1386|Bacillus 91061|Bacilli O cytochrome c biogenesis protein ccdA - - ko:K06196 - - - - ko00000,ko02000 5.A.1.2 - - DsbD k141_6406_2 1453501.JELR01000002_gene1073 1.17e-104 305.0 COG3175@1|root,COG3175@2|Bacteria,1RDTU@1224|Proteobacteria,1S5XA@1236|Gammaproteobacteria,466DV@72275|Alteromonadaceae 1236|Gammaproteobacteria O oxidase assembly ctaG - - ko:K02258 ko00190,ko01100,ko04714,map00190,map01100,map04714 M00154 - - ko00000,ko00001,ko00002,ko03029 3.D.4.8 - - CtaG_Cox11 k141_5102_2 1234664.AMRO01000050_gene389 9.61e-06 44.7 299WW@1|root,2ZWYR@2|Bacteria,1W2E5@1239|Firmicutes,4I1XT@91061|Bacilli,1WH3Q@129337|Geobacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_5102_3 1294265.JCM21738_2291 1.24e-08 53.1 2EP6J@1|root,33GT9@2|Bacteria,1VMWE@1239|Firmicutes,4HS59@91061|Bacilli,1ZIQP@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_25315_1 218284.CCDN010000001_gene21 2.06e-84 261.0 COG0541@1|root,COG0541@2|Bacteria,1TP06@1239|Firmicutes,4H9T4@91061|Bacilli,1ZB4I@1386|Bacillus 91061|Bacilli U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY ffh - 3.6.5.4 ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko01000,ko02044 3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9 - - SRP54,SRP54_N,SRP_SPB k141_25315_2 796606.BMMGA3_05990 9.95e-49 157.0 COG2739@1|root,COG2739@2|Bacteria,1VEGP@1239|Firmicutes,4HKK6@91061|Bacilli,1ZH7Z@1386|Bacillus 91061|Bacilli S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein ylxM GO:0003674,GO:0008150,GO:0030234,GO:0030695,GO:0050790,GO:0060589,GO:0065007,GO:0065009,GO:0098772 - ko:K09787 - - - - ko00000 - - - UPF0122 k141_21752_1 1294265.JCM21738_1965 8.48e-75 224.0 COG1695@1|root,COG1695@2|Bacteria,1V4NA@1239|Firmicutes,4HHWW@91061|Bacilli,1ZINR@1386|Bacillus 91061|Bacilli K Transcriptional regulator PadR-like family - - - ko:K10947 - - - - ko00000,ko03000 - - - PadR k141_21752_2 1294265.JCM21738_1964 4.72e-19 82.8 28MY0@1|root,2ZB4Y@2|Bacteria,1V0KB@1239|Firmicutes,4HE2C@91061|Bacilli,1ZE6E@1386|Bacillus 91061|Bacilli - - ywdD - - - - - - - - - - - - k141_14575_2 1116375.VEJY3_01670 9.68e-158 445.0 COG0398@1|root,COG0398@2|Bacteria,1RBAE@1224|Proteobacteria,1S32X@1236|Gammaproteobacteria,1XU6W@135623|Vibrionales 135623|Vibrionales S Protein of unknown function, DUF547 VV0483 - - - - - - - - - - - DUF547 k141_14575_3 223926.28805325 3.61e-142 401.0 COG0066@1|root,COG0066@2|Bacteria,1MVXB@1224|Proteobacteria,1RNMK@1236|Gammaproteobacteria,1XT0W@135623|Vibrionales 135623|Vibrionales E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate leuD GO:0003674,GO:0003824,GO:0003861,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009316,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.2.1.33,4.2.1.35 ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R10170 RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase_C k141_14575_4 1116375.VEJY3_01680 0.0 900.0 COG0065@1|root,COG0065@2|Bacteria,1MVYR@1224|Proteobacteria,1RMF6@1236|Gammaproteobacteria,1XT5K@135623|Vibrionales 135623|Vibrionales H Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate leuC GO:0003674,GO:0003824,GO:0003861,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009316,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.2.1.33,4.2.1.35 ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170 RC00497,RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase k141_14575_5 223926.28805327 2.12e-54 179.0 COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,1RMZQ@1236|Gammaproteobacteria,1XTG7@135623|Vibrionales 135623|Vibrionales CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate leuB GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R00994,R04426,R10052 RC00084,RC00417,RC03036 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh k141_33626_1 1453501.JELR01000002_gene763 4.26e-184 534.0 COG0834@1|root,COG4623@1|root,COG0834@2|Bacteria,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,1RM8W@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella - GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - ko:K18691 - - - - ko00000,ko01000,ko01011 - - - SBP_bac_3,SLT k141_5103_1 218284.CCDN010000001_gene735 5.23e-97 291.0 COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,4H9KA@91061|Bacilli,1ZC0R@1386|Bacillus 91061|Bacilli O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins dnaJ - - ko:K03686 - - - - ko00000,ko03029,ko03110 - - - DnaJ,DnaJ_C,DnaJ_CXXCXGXG k141_20486_2 1462527.CCDM010000001_gene2305 1.84e-07 53.5 COG4729@1|root,COG4729@2|Bacteria,1VCAR@1239|Firmicutes,4HM9T@91061|Bacilli,23K9S@182709|Oceanobacillus 91061|Bacilli S Domain of unknown function (DUF1850) - - - - - - - - - - - - DUF1850 k141_28899_1 218284.CCDN010000001_gene769 4.01e-134 390.0 COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,4HA98@91061|Bacilli,1ZDG5@1386|Bacillus 91061|Bacilli JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures cshB GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0070035,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 3.6.4.13 ko:K05592,ko:K18692 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,Helicase_C k141_6407_1 218284.CCDN010000002_gene2281 1.23e-59 189.0 COG2186@1|root,COG2186@2|Bacteria,1V5E3@1239|Firmicutes,4HI4R@91061|Bacilli,1ZGPE@1386|Bacillus 91061|Bacilli K FadR C-terminal domain - - - ko:K03603 - - - - ko00000,ko03000 - - - FadR_C,GntR k141_6407_2 218284.CCDN010000002_gene2280 6.34e-61 191.0 COG3000@1|root,COG3000@2|Bacteria,1V2XN@1239|Firmicutes,4HFS5@91061|Bacilli,1ZGHZ@1386|Bacillus 91061|Bacilli I Fatty acid hydroxylase - - - - - - - - - - - - FA_hydroxylase k141_31372_2 674977.VMC_08380 1.06e-144 408.0 COG0357@1|root,COG0357@2|Bacteria,1MY0K@1224|Proteobacteria,1RMRZ@1236|Gammaproteobacteria,1XSMQ@135623|Vibrionales 135623|Vibrionales J Specifically methylates the N7 position of guanine in position 527 of 16S rRNA rsmG GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 ko:K03501 - - - - ko00000,ko01000,ko03009,ko03036 - - - GidB k141_31372_3 223926.28808104 2.03e-174 487.0 COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,1RNJK@1236|Gammaproteobacteria,1XT92@135623|Vibrionales 135623|Vibrionales D COG1192 ATPases involved in chromosome partitioning parA - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 k141_31372_4 1116375.VEJY3_15490 3.66e-179 502.0 COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,1RN65@1236|Gammaproteobacteria,1XUPW@135623|Vibrionales 135623|Vibrionales K Belongs to the ParB family parB - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc k141_31372_5 1116375.VEJY3_15485 2.9e-75 226.0 COG3312@1|root,COG3312@2|Bacteria,1N777@1224|Proteobacteria,1SD0Z@1236|Gammaproteobacteria,1XXAB@135623|Vibrionales 135623|Vibrionales C COG3312 F0F1-type ATP synthase, subunit I atpI GO:0003674,GO:0003824,GO:0005215,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044769,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02116 - - - - ko00000,ko00194 3.A.2.1 - - ATP-synt_I k141_31372_6 1219076.N646_2175 6.38e-191 530.0 COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,1RPHK@1236|Gammaproteobacteria,1XT0C@135623|Vibrionales 135623|Vibrionales C it plays a direct role in the translocation of protons across the membrane atpB GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 - - ATP-synt_A k141_31372_7 55601.VANGNB10_cI2705c 7.13e-46 148.0 COG0636@1|root,32S3K@2|Bacteria,1N1NA@1224|Proteobacteria,1S9MD@1236|Gammaproteobacteria,1XYCJ@135623|Vibrionales 135623|Vibrionales C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpE GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_C k141_31372_8 223926.28808099 1.21e-73 224.0 COG0711@1|root,COG0711@2|Bacteria,1RHZ0@1224|Proteobacteria,1S402@1236|Gammaproteobacteria,1XVBF@135623|Vibrionales 135623|Vibrionales C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) atpF GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_B k141_31372_9 223926.28808098 2.49e-115 331.0 COG0712@1|root,COG0712@2|Bacteria,1MVRH@1224|Proteobacteria,1S8X2@1236|Gammaproteobacteria,1XU7W@135623|Vibrionales 135623|Vibrionales C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpH GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - OSCP k141_31372_10 1280001.BAOA01000052_gene1616 0.0 965.0 COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,1RP4V@1236|Gammaproteobacteria,1XUW5@135623|Vibrionales 135623|Vibrionales C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit atpA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N k141_31372_11 223926.28808096 1.29e-197 548.0 COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,1RNWJ@1236|Gammaproteobacteria,1XTEZ@135623|Vibrionales 135623|Vibrionales C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex atpG GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt k141_31372_13 1116375.VEJY3_15445 3.84e-92 270.0 COG0355@1|root,COG0355@2|Bacteria,1RHE4@1224|Proteobacteria,1S25H@1236|Gammaproteobacteria,1XWUZ@135623|Vibrionales 135623|Vibrionales C Produces ATP from ADP in the presence of a proton gradient across the membrane atpC GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_DE,ATP-synt_DE_N k141_24373_1 279010.BL03456 1.21e-62 197.0 COG0247@1|root,COG0247@2|Bacteria,1TPFC@1239|Firmicutes,4HAKC@91061|Bacilli,1ZCUT@1386|Bacillus 91061|Bacilli C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source lutA - - ko:K18928 - - - - ko00000 - - - CCG k141_24373_2 935836.JAEL01000083_gene1122 2.07e-33 125.0 COG1139@1|root,COG1139@2|Bacteria,1TREQ@1239|Firmicutes,4H9UI@91061|Bacilli,1ZCJB@1386|Bacillus 91061|Bacilli C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate lutB - - ko:K18929 - - - - ko00000 - - - DUF3390,Fer4_8,LUD_dom k141_19700_2 218284.CCDN010000001_gene1181 3.58e-48 159.0 COG0328@1|root,COG0328@2|Bacteria,1V3K2@1239|Firmicutes,4HE8H@91061|Bacilli,1ZDMZ@1386|Bacillus 91061|Bacilli L COG0328 Ribonuclease HI ypeP - 3.1.26.4 ko:K03469 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RVT_3 k141_10274_1 1121930.AQXG01000002_gene2392 4.09e-29 117.0 COG3391@1|root,COG3391@2|Bacteria 2|Bacteria CO amine dehydrogenase activity - - - - - - - - - - - - Cu_amine_oxidN1,Phytase-like k141_31385_1 1294265.JCM21738_2680 8.73e-42 137.0 2DPJX@1|root,332FH@2|Bacteria,1VF9T@1239|Firmicutes,4HPCA@91061|Bacilli,1ZIV2@1386|Bacillus 91061|Bacilli S Spore germination protein gerPA GO:0000003,GO:0008150,GO:0009847,GO:0019954,GO:0030436,GO:0032502,GO:0043934 - ko:K06299 - - - - ko00000 - - - gerPA k141_31385_2 1294265.JCM21738_2679 5.09e-35 120.0 2EBHF@1|root,335HY@2|Bacteria,1VHMW@1239|Firmicutes,4HPZZ@91061|Bacilli,1ZIW2@1386|Bacillus 91061|Bacilli S cell differentiation gerPB - - ko:K06300 - - - - ko00000 - - - GerPB k141_17230_1 935836.JAEL01000008_gene3887 5.74e-151 434.0 COG1680@1|root,COG1680@2|Bacteria,1TYVU@1239|Firmicutes,4HE5K@91061|Bacilli,1ZCMW@1386|Bacillus 91061|Bacilli V Beta-lactamase - - - - - - - - - - - - Beta-lactamase k141_16056_1 84531.JMTZ01000002_gene804 8.95e-06 48.5 COG2267@1|root,COG2267@2|Bacteria,1NTH9@1224|Proteobacteria,1S7N8@1236|Gammaproteobacteria,1XCA5@135614|Xanthomonadales 135614|Xanthomonadales I Serine aminopeptidase, S33 - - - - - - - - - - - - Abhydrolase_1 k141_16056_2 1517416.IDAT_09050 8.51e-125 388.0 COG1629@1|root,COG4771@2|Bacteria,1MWKN@1224|Proteobacteria,1RMM6@1236|Gammaproteobacteria,2QFW6@267893|Idiomarinaceae 1236|Gammaproteobacteria P TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_27782_2 1294265.JCM21738_95 1.64e-72 220.0 COG0204@1|root,COG0204@2|Bacteria,1U8N2@1239|Firmicutes,4HDQR@91061|Bacilli,1ZE5P@1386|Bacillus 91061|Bacilli I 1-acyl-sn-glycerol-3-phosphate acyltransferase plsC - 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase k141_29100_1 218284.CCDN010000004_gene3154 4.84e-119 349.0 COG4399@1|root,COG4399@2|Bacteria,1TQDH@1239|Firmicutes,4HA30@91061|Bacilli,1ZB1W@1386|Bacillus 91061|Bacilli S Belongs to the UPF0754 family yheB - - - - - - - - - - - DUF445 k141_13902_1 1279017.AQYJ01000027_gene1938 1.18e-290 803.0 COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,1RNQM@1236|Gammaproteobacteria,463Y4@72275|Alteromonadaceae 1236|Gammaproteobacteria S Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis ubiB GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016020,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901576,GO:1901661,GO:1901663 - ko:K03688 - - - - ko00000 - - iYL1228.KPN_04331 ABC1 k141_13902_2 1279017.AQYJ01000027_gene1937 2.09e-28 108.0 COG3165@1|root,COG3165@2|Bacteria,1R1CM@1224|Proteobacteria,1S1SM@1236|Gammaproteobacteria,4689F@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria yigP - - ko:K03690 - - - - ko00000 - - - SCP2 k141_4227_2 218284.CCDN010000001_gene381 1.23e-47 154.0 2E1U1@1|root,32X3Q@2|Bacteria,1VD0Y@1239|Firmicutes,4HNCK@91061|Bacilli,1ZHYC@1386|Bacillus 91061|Bacilli S YtpI-like protein ytpI - - - - - - - - - - - YtpI k141_10275_1 218284.CCDN010000001_gene497 1.12e-97 289.0 28NMK@1|root,2ZBN3@2|Bacteria,1TT4K@1239|Firmicutes,4HBFT@91061|Bacilli,1ZCHB@1386|Bacillus 91061|Bacilli U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane amj - - - - - - - - - - - Amj k141_30187_1 218284.CCDN010000001_gene1650 1.26e-102 302.0 COG1028@1|root,COG1028@2|Bacteria,1TQ80@1239|Firmicutes,4HASE@91061|Bacilli,1ZD1G@1386|Bacillus 91061|Bacilli IQ Enoyl-(Acyl carrier protein) reductase - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 k141_36167_1 1220589.CD32_08470 1.16e-43 156.0 COG0642@1|root,COG2205@2|Bacteria,1V10X@1239|Firmicutes,4HB4P@91061|Bacilli,3IWRS@400634|Lysinibacillus 91061|Bacilli T membrane hssS - - - - - - - - - - - HAMP,HATPase_c,HisKA k141_36167_2 1196031.ALEG01000041_gene2754 4.54e-71 216.0 2DN3I@1|root,32VBH@2|Bacteria,1VB51@1239|Firmicutes,4HKZM@91061|Bacilli,1ZI4Y@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_24374_1 522373.Smlt3475 2.39e-63 204.0 COG2968@1|root,COG2968@2|Bacteria,1RH7T@1224|Proteobacteria,1RP7T@1236|Gammaproteobacteria,1X44K@135614|Xanthomonadales 135614|Xanthomonadales S Protein of unknown function (DUF541) - - - ko:K09807 - - - - ko00000 - - - SIMPL k141_16057_1 218284.CCDN010000002_gene2705 2.31e-37 127.0 2E6JV@1|root,334AK@2|Bacteria,1VIDD@1239|Firmicutes,4HQJG@91061|Bacilli 91061|Bacilli S Domain of unknown function (DUF3784) - - - - - - - - - - - - DUF3784 k141_16057_2 218284.CCDN010000002_gene2706 3.45e-42 145.0 COG0596@1|root,COG0596@2|Bacteria,1TRAQ@1239|Firmicutes,4HCI9@91061|Bacilli,1ZQW6@1386|Bacillus 91061|Bacilli S Alpha/beta hydrolase family pip - 3.4.11.5 ko:K01259 ko00330,map00330 - R00135 - ko00000,ko00001,ko01000,ko01002 - - - Abhydrolase_1 k141_7682_1 218284.CCDN010000001_gene1530 8.47e-99 286.0 COG1051@1|root,COG1051@2|Bacteria,1VBCP@1239|Firmicutes,4HMIG@91061|Bacilli,1ZHZ2@1386|Bacillus 91061|Bacilli F Belongs to the Nudix hydrolase family - - - - - - - - - - - - NUDIX k141_19702_1 631454.N177_1637 6.11e-43 153.0 COG1149@1|root,COG1149@2|Bacteria,1QTYV@1224|Proteobacteria,2TTH3@28211|Alphaproteobacteria 28211|Alphaproteobacteria C TIGRFAM CitB domain protein tcuB - - ko:K13795 - - - - ko00000 - - - - k141_18573_1 218284.CCDN010000001_gene1231 4.49e-214 601.0 COG0793@1|root,COG0793@2|Bacteria,1TPBI@1239|Firmicutes,4HAKE@91061|Bacilli,1ZBDE@1386|Bacillus 91061|Bacilli M Belongs to the peptidase S41A family ctpA GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016787,GO:0019538,GO:0023052,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - PDZ,PDZ_2,PG_binding_1,Peptidase_S41 k141_5495_1 1453501.JELR01000002_gene851 5.49e-91 271.0 COG2186@1|root,COG2186@2|Bacteria,1MY1K@1224|Proteobacteria,1RMUE@1236|Gammaproteobacteria,46CKF@72275|Alteromonadaceae 1236|Gammaproteobacteria K FCD - - - - - - - - - - - - FCD,GntR k141_763_1 1116375.VEJY3_11375 2.12e-244 687.0 COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,1RMZ8@1236|Gammaproteobacteria,1XV3W@135623|Vibrionales 135623|Vibrionales I Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities fadJ GO:0003674,GO:0003824,GO:0003857,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008692,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0016856,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 1.1.1.35,4.2.1.17,5.1.2.3 ko:K01782 ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212 M00032,M00087 R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094 RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 - - - 3HCDH,3HCDH_N,ECH_1 k141_763_2 1116375.VEJY3_11380 5.3e-255 703.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RNGU@1236|Gammaproteobacteria,1XSJ5@135623|Vibrionales 135623|Vibrionales I Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed fadI GO:0003674,GO:0003824,GO:0003988,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 2.3.1.16 ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 M00087,M00113 R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095 RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955 ko00000,ko00001,ko00002,ko01000 - - - Thiolase_C,Thiolase_N k141_29101_1 218284.CCDN010000005_gene3451 3.65e-86 273.0 COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4HBBB@91061|Bacilli,1ZCKA@1386|Bacillus 91061|Bacilli M Penicillin-binding Protein pbpD - 2.4.1.129,3.4.16.4 ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase k141_6595_2 935837.JAEK01000006_gene4240 7.52e-61 195.0 COG3711@1|root,COG3711@2|Bacteria,1TT5A@1239|Firmicutes,4HC5Y@91061|Bacilli,1ZDB0@1386|Bacillus 91061|Bacilli K transcriptional antiterminator sacT - - ko:K03488 - - - - ko00000,ko03000 - - - CAT_RBD,PRD k141_27784_1 218284.CCDN010000005_gene3294 7.06e-77 235.0 COG0741@1|root,COG0741@2|Bacteria,1V6DD@1239|Firmicutes,4HIWA@91061|Bacilli,1ZH33@1386|Bacillus 91061|Bacilli M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) yjbJ - - - - - - - - - - - SLT k141_10276_1 1294265.JCM21738_364 5.87e-148 420.0 COG0726@1|root,COG0726@2|Bacteria,1TQ5M@1239|Firmicutes,4HAHC@91061|Bacilli,1ZC6V@1386|Bacillus 91061|Bacilli G Sporulation protein, polysaccharide deacetylase ylxY GO:0005575,GO:0016020 - - - - - - - - - - Polysacc_deac_1 k141_12696_1 1453501.JELR01000005_gene1688 3.57e-105 312.0 COG2041@1|root,COG2041@2|Bacteria,1MUW0@1224|Proteobacteria,1RQ2J@1236|Gammaproteobacteria,464E2@72275|Alteromonadaceae 1236|Gammaproteobacteria C Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide msrP GO:0000302,GO:0001101,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0016491,GO:0016667,GO:0016672,GO:0016675,GO:0019538,GO:0030091,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042597,GO:0043170,GO:0043546,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0048037,GO:0050662,GO:0050896,GO:0055114,GO:0071704,GO:0097159,GO:1901363,GO:1901530,GO:1901564,GO:1901700 - ko:K07147 - - - - ko00000,ko01000 - - - Oxidored_molyb k141_23319_1 218284.CCDN010000005_gene3243 1.57e-62 198.0 COG1562@1|root,COG1562@2|Bacteria,1TQHF@1239|Firmicutes,4HA1A@91061|Bacilli,1ZCIV@1386|Bacillus 91061|Bacilli I phytoene crtM - 2.5.1.32,2.5.1.99 ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 M00097 R02065,R04218,R07270,R10177 RC00362,RC01101,RC02869 ko00000,ko00001,ko00002,ko01000,ko01006 - - - SQS_PSY k141_31386_2 1122927.KB895413_gene1573 1.54e-35 131.0 2EVWJ@1|root,33PA8@2|Bacteria,1VNYN@1239|Firmicutes,4IRMI@91061|Bacilli,272CN@186822|Paenibacillaceae 91061|Bacilli - - - - - - - - - - - - - - - k141_30188_1 218284.CCDN010000005_gene3445 2.59e-107 323.0 COG0651@1|root,COG0651@2|Bacteria,1TRAT@1239|Firmicutes,4HA10@91061|Bacilli,1ZB2A@1386|Bacillus 91061|Bacilli CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali mrpD GO:0003674,GO:0005215,GO:0005451,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015491,GO:0015672,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0035725,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0098655,GO:0098660,GO:0098662,GO:0099516,GO:1902600 - ko:K05568 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - iSB619.SA_RS04615 Proton_antipo_M k141_20754_1 1128421.JAGA01000002_gene970 6.9e-68 219.0 COG0017@1|root,COG0017@2|Bacteria,2NNQM@2323|unclassified Bacteria 2|Bacteria J tRNA synthetases class II (D, K and N) asnS GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.22 ko:K01893 ko00970,map00970 M00359,M00360 R03648 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2,tRNA_anti-codon k141_32580_2 218284.CCDN010000005_gene3219 6.4e-78 233.0 2ATJK@1|root,31J3N@2|Bacteria,1V8E1@1239|Firmicutes,4HK5R@91061|Bacilli,1ZH24@1386|Bacillus 91061|Bacilli - - yhjD - - - - - - - - - - - - k141_32580_3 218284.CCDN010000005_gene3218 2.99e-72 223.0 COG4903@1|root,COG4903@2|Bacteria,1V4S5@1239|Firmicutes,4HHF4@91061|Bacilli,1ZGB4@1386|Bacillus 91061|Bacilli K Competence transcription factor comK - - ko:K02250 ko02024,map02024 - - - ko00000,ko00001,ko02044,ko03000 - - - ComK k141_22011_1 1294265.JCM21738_3737 9.05e-61 192.0 COG0563@1|root,COG0563@2|Bacteria,1TP27@1239|Firmicutes,4HA89@91061|Bacilli,1ZBYM@1386|Bacillus 91061|Bacilli F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism adk GO:0003674,GO:0003824,GO:0004017,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ADK,ADK_lid k141_4228_1 861299.J421_3121 8.39e-95 288.0 COG1493@1|root,COG1493@2|Bacteria,1ZSY3@142182|Gemmatimonadetes 142182|Gemmatimonadetes H Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) hprK - - ko:K06023 - - - - ko00000,ko01000 - - - Hpr_kinase_C,Hpr_kinase_N k141_764_1 1280001.BAOA01000078_gene3131 4.6e-48 164.0 COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,1SN04@1236|Gammaproteobacteria,1XURU@135623|Vibrionales 135623|Vibrionales P Rhodanese Homology Domain - - 2.8.1.1,2.8.1.2 ko:K01011 ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122 - R01931,R03105,R03106 RC00214 ko00000,ko00001,ko01000 - - - Rhodanese k141_10277_1 1042377.AFPJ01000036_gene1283 2.43e-44 150.0 COG1514@1|root,COG1514@2|Bacteria,1RDB2@1224|Proteobacteria,1SCZX@1236|Gammaproteobacteria,4690I@72275|Alteromonadaceae 1236|Gammaproteobacteria J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester ligT GO:0003674,GO:0003824,GO:0004112,GO:0004113,GO:0008081,GO:0008452,GO:0008664,GO:0016787,GO:0016788,GO:0016874,GO:0016886,GO:0042578,GO:0140098 3.1.4.58 ko:K01975 - - - - ko00000,ko01000,ko03016 - - - LigT_PEase k141_27005_3 1042377.AFPJ01000025_gene624 2.72e-314 860.0 COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RMFF@1236|Gammaproteobacteria,463YH@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes lpdG GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - iE2348C_1286.E2348C_4372,iJN746.PP_4187 Pyr_redox_2,Pyr_redox_dim k141_27005_4 1279017.AQYJ01000024_gene1139 1.22e-222 621.0 COG0508@1|root,COG0508@2|Bacteria,1MUJD@1224|Proteobacteria,1RME0@1236|Gammaproteobacteria,464AW@72275|Alteromonadaceae 1236|Gammaproteobacteria C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) sucB GO:0003674,GO:0003824,GO:0004149,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0008289,GO:0009060,GO:0009987,GO:0015980,GO:0016417,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016751,GO:0016999,GO:0017144,GO:0019752,GO:0031405,GO:0031406,GO:0032991,GO:0033293,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045333,GO:0048037,GO:0050662,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:0140096,GO:1901363,GO:1901681,GO:1902494,GO:1990204,GO:1990234 2.3.1.61 ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R02570,R02571,R08549 RC00004,RC02727,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_1352,iECED1_1282.ECED1_0696,iECOK1_1307.ECOK1_0726,iECS88_1305.ECS88_0752,iLF82_1304.LF82_2196,iNRG857_1313.NRG857_03235,iUMN146_1321.UM146_13990,iUTI89_1310.UTI89_C0722 2-oxoacid_dh,Biotin_lipoyl,E3_binding k141_27005_5 1453501.JELR01000002_gene92 0.0 1774.0 COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,1RN8K@1236|Gammaproteobacteria,465AY@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes sucA GO:0003674,GO:0003824,GO:0004591,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016624,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045333,GO:0055114,GO:0071704,GO:0072350,GO:1902494,GO:1990204,GO:1990234 1.2.4.2 ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R00621,R01933,R01940,R03316,R08549 RC00004,RC00027,RC00627,RC02743,RC02833,RC02883 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr k141_27005_7 1279017.AQYJ01000024_gene1136 0.0 1091.0 COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,1RMU2@1236|Gammaproteobacteria,4646I@72275|Alteromonadaceae 1236|Gammaproteobacteria C Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily sdhA GO:0000104,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - iE2348C_1286.E2348C_0603,iJN746.PP_4191,iPC815.YPO1111 FAD_binding_2,Succ_DH_flav_C k141_27005_10 1279017.AQYJ01000024_gene1133 6.72e-301 822.0 COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,1RNDK@1236|Gammaproteobacteria,464XQ@72275|Alteromonadaceae 1236|Gammaproteobacteria C Belongs to the citrate synthase family gltA GO:0003674,GO:0003824,GO:0004108,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016740,GO:0016746,GO:0016999,GO:0017144,GO:0019752,GO:0036440,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046912,GO:0055114,GO:0071704,GO:0072350 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 - - iYL1228.KPN_00727 Citrate_synt k141_23320_1 1294265.JCM21738_2954 3.49e-136 399.0 COG0367@1|root,COG0367@2|Bacteria,1TRPB@1239|Firmicutes,4HAIP@91061|Bacilli,1ZAPW@1386|Bacillus 91061|Bacilli E Asparagine synthase asnB - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 k141_27785_1 935837.JAEK01000006_gene4241 2.63e-118 351.0 COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli,1ZB5X@1386|Bacillus 91061|Bacilli G phosphotransferase system sacP GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563 2.7.1.211 ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 M00269 R00811 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.1,4.A.1.2.10,4.A.1.2.12,4.A.1.2.9 - iYO844.BSU38050 PTS_EIIB,PTS_EIIC k141_16058_1 218284.CCDN010000005_gene3379 1.84e-83 248.0 COG1846@1|root,COG1846@2|Bacteria,1VB3Q@1239|Firmicutes,4IR3G@91061|Bacilli,1ZRRC@1386|Bacillus 91061|Bacilli K Winged helix DNA-binding domain - - - ko:K15973 - - - - ko00000,ko03000 - - - MarR k141_16058_2 218284.CCDN010000005_gene3380 1.31e-91 285.0 COG1164@1|root,COG1164@2|Bacteria,1TPV4@1239|Firmicutes,4HAJJ@91061|Bacilli,1ZD3W@1386|Bacillus 91061|Bacilli E oligoendopeptidase pepF - - - - - - - - - - - Peptidase_M3 k141_6597_1 1294265.JCM21738_131 5.34e-80 239.0 COG0723@1|root,COG0723@2|Bacteria,1TQUH@1239|Firmicutes,4HBX1@91061|Bacilli,1ZFNX@1386|Bacillus 91061|Bacilli C Menaquinol-cytochrome c reductase qcrA - - ko:K03886 ko00190,ko01100,map00190,map01100 M00151 - - ko00000,ko00001,ko00002,ko01000 - - - CytB6-F_Fe-S,Rieske k141_7683_1 1294265.JCM21738_5023 5.98e-33 116.0 COG3871@1|root,COG3871@2|Bacteria,1V6MX@1239|Firmicutes,4HIYZ@91061|Bacilli,1ZH2Z@1386|Bacillus 91061|Bacilli S general stress protein ydaG - - - - - - - - - - - Putative_PNPOx,Pyrid_ox_like k141_7683_2 1294265.JCM21738_5024 6.74e-44 143.0 2ET31@1|root,33P5S@2|Bacteria,1VPET@1239|Firmicutes,4HRIW@91061|Bacilli,1ZJ9V@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_25719_1 218284.CCDN010000001_gene1256 6.77e-135 391.0 COG2378@1|root,COG2378@2|Bacteria,1TSA2@1239|Firmicutes,4HCDN@91061|Bacilli,1ZD8Z@1386|Bacillus 91061|Bacilli K WYL domain - - - - - - - - - - - - WYL k141_25719_2 66692.ABC3028 1.13e-23 92.8 COG3296@1|root,COG3296@2|Bacteria,1VJNI@1239|Firmicutes,4HKFS@91061|Bacilli,1ZQSE@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF4870) - - - ko:K09940 - - - - ko00000 - - - DUF4870 k141_13903_2 1116375.VEJY3_24351 1.09e-114 331.0 COG0668@1|root,COG0668@2|Bacteria,1MZKZ@1224|Proteobacteria,1S6N8@1236|Gammaproteobacteria,1XTNK@135623|Vibrionales 135623|Vibrionales M Mechanosensitive ion channel - - - - - - - - - - - - MS_channel k141_13903_3 1116375.VEJY3_24356 3.08e-169 485.0 COG4166@1|root,COG4166@2|Bacteria,1P91R@1224|Proteobacteria,1RN57@1236|Gammaproteobacteria,1XVN1@135623|Vibrionales 135623|Vibrionales E Bacterial extracellular solute-binding proteins, family 5 Middle - - - ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 k141_36169_1 446469.Sked_36590 5.33e-20 90.9 COG0451@1|root,COG0451@2|Bacteria,2GMHH@201174|Actinobacteria 201174|Actinobacteria M 3-beta hydroxysteroid dehydrogenase isomerase - GO:0000166,GO:0003674,GO:0003824,GO:0003854,GO:0004769,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006629,GO:0008150,GO:0008152,GO:0008202,GO:0016020,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0016853,GO:0016860,GO:0016863,GO:0030283,GO:0033764,GO:0036094,GO:0043167,GO:0043168,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0071944,GO:0097159,GO:1901265,GO:1901360,GO:1901363 1.1.1.145,1.1.1.412,5.3.3.1 ko:K16045,ko:K22320 ko00984,ko01120,map00984,map01120 - R09920 RC00146 ko00000,ko00001,ko01000 - - - 3Beta_HSD,Epimerase k141_20755_1 1392838.AWNM01000038_gene941 6.45e-49 168.0 COG4608@1|root,COG4608@2|Bacteria,1NU4K@1224|Proteobacteria,2W19X@28216|Betaproteobacteria,3T267@506|Alcaligenaceae 28216|Betaproteobacteria P Belongs to the ABC transporter superfamily - - - ko:K02032 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - ABC_tran,oligo_HPY k141_4229_1 218284.CCDN010000005_gene3385 1.51e-111 330.0 COG0520@1|root,COG0520@2|Bacteria,1TQ1W@1239|Firmicutes,4HA6Z@91061|Bacilli,1ZB79@1386|Bacillus 91061|Bacilli E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine sufS - 2.8.1.7,4.4.1.16 ko:K11717 ko00450,ko01100,map00450,map01100 - R03599,R11528 RC00961,RC01789,RC02313 ko00000,ko00001,ko01000 - - - Aminotran_5 k141_9001_2 1348635.BBJY01000048_gene1971 3.7e-218 605.0 COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,1RMAQ@1236|Gammaproteobacteria,1XWQE@135623|Vibrionales 135623|Vibrionales L COG3547 Transposase and inactivated derivatives - - - - - - - - - - - - DEDD_Tnp_IS110,Transposase_20 k141_9001_3 1027273.GZ77_23200 5.37e-40 137.0 2FHQS@1|root,349IB@2|Bacteria,1P188@1224|Proteobacteria,1SSJR@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_9001_4 1027273.GZ77_23195 0.0 979.0 COG0582@1|root,COG0582@2|Bacteria,1R9JZ@1224|Proteobacteria,1RY18@1236|Gammaproteobacteria 1236|Gammaproteobacteria L viral genome integration into host DNA - - - - - - - - - - - - - k141_9001_5 1027273.GZ77_23190 0.0 899.0 COG0582@1|root,COG0582@2|Bacteria,1PTDF@1224|Proteobacteria,1RY2D@1236|Gammaproteobacteria 1236|Gammaproteobacteria L viral genome integration into host DNA - - - - - - - - - - - - - k141_10312_1 223926.28806966 6.59e-55 188.0 COG0620@1|root,COG0620@2|Bacteria,1MUI9@1224|Proteobacteria,1RMBA@1236|Gammaproteobacteria,1XSM3@135623|Vibrionales 135623|Vibrionales E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation metE GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0042085,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050667,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_1,Meth_synt_2 k141_10312_2 223926.28806965 1.79e-69 211.0 2B0AA@1|root,31SMA@2|Bacteria,1QJXS@1224|Proteobacteria,1THZX@1236|Gammaproteobacteria,1XY1G@135623|Vibrionales 135623|Vibrionales S Type II secretion system (T2SS) pilotin, S protein - - - - - - - - - - - - T2SSS_2 k141_10312_3 1219076.N646_1053 1.53e-60 186.0 COG2350@1|root,COG2350@2|Bacteria,1MZ9Z@1224|Proteobacteria,1S8UC@1236|Gammaproteobacteria,1XXWF@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria yciI - - ko:K09780 - - - - ko00000 - - - YCII k141_10312_4 1116375.VEJY3_10320 1.01e-85 253.0 COG1607@1|root,COG1607@2|Bacteria,1MZAZ@1224|Proteobacteria,1SA9N@1236|Gammaproteobacteria,1XWWY@135623|Vibrionales 135623|Vibrionales I COG1607 Acyl-CoA hydrolase yciA - - ko:K10806 ko01040,map01040 - - - ko00000,ko00001,ko01000,ko01004 - - - 4HBT k141_10312_5 1116375.VEJY3_10315 8.9e-123 351.0 COG2917@1|root,COG2917@2|Bacteria,1NWIZ@1224|Proteobacteria,1RQAB@1236|Gammaproteobacteria,1XT4H@135623|Vibrionales 135623|Vibrionales D probably involved in intracellular septation ispZ - - ko:K06190 - - - - ko00000 - - - IspA k141_10312_6 1116375.VEJY3_10305 0.0 1147.0 COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1R81Y@1224|Proteobacteria,1RYQ2@1236|Gammaproteobacteria,1XUTT@135623|Vibrionales 135623|Vibrionales T COG0642 Signal transduction histidine kinase luxN - 2.7.13.3 ko:K15850 ko02020,ko02024,map02020,map02024 - - - ko00000,ko00001,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,Response_reg k141_10312_7 1187848.AJYQ01000004_gene196 5.16e-239 677.0 COG0471@1|root,COG0490@1|root,COG0471@2|Bacteria,COG0490@2|Bacteria,1MU0K@1224|Proteobacteria,1RMI1@1236|Gammaproteobacteria,1XTKK@135623|Vibrionales 135623|Vibrionales P COG0471 Di- and tricarboxylate transporters - - - - - - - - - - - - CitMHS,TrkA_C k141_10312_8 1187848.AJYQ01000004_gene197 9.09e-206 570.0 COG0175@1|root,COG0175@2|Bacteria,1MUCZ@1224|Proteobacteria,1RNAD@1236|Gammaproteobacteria,1XTPJ@135623|Vibrionales 135623|Vibrionales H Sulfate adenylyltransferase subunit 2 cysD - 2.7.7.4 ko:K00957 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176,M00596 R00529,R04929 RC02809,RC02889 ko00000,ko00001,ko00002,ko01000 - - - PAPS_reduct k141_32610_2 1243664.CAVL020000048_gene2486 1.53e-21 93.6 COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,4HAM7@91061|Bacilli,1ZBG8@1386|Bacillus 91061|Bacilli E COG0747 ABC-type dipeptide transport system, periplasmic component dppA - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 k141_24424_1 998088.B565_2542 4.04e-61 200.0 COG4658@1|root,COG4658@2|Bacteria,1MVY6@1224|Proteobacteria,1RMEU@1236|Gammaproteobacteria,1Y402@135624|Aeromonadales 135624|Aeromonadales C Part of a membrane complex involved in electron transport rnfD - - ko:K03614 - - - - ko00000 - - - NQR2_RnfD_RnfE k141_9033_1 575788.VS_1966 6e-20 88.6 COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,1RMSE@1236|Gammaproteobacteria,1XSGC@135623|Vibrionales 135623|Vibrionales E COG0147 Anthranilate para-aminobenzoate synthases component I trpE GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.1.3.27 ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Anth_synt_I_N,Chorismate_bind k141_9033_2 1116375.VEJY3_10260 3.63e-127 363.0 COG0512@1|root,COG0512@2|Bacteria,1RAKJ@1224|Proteobacteria,1RREB@1236|Gammaproteobacteria,1XTCZ@135623|Vibrionales 135623|Vibrionales EH COG0512 Anthranilate para-aminobenzoate synthases component II trpG GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.1.3.27 ko:K01658 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - GATase k141_9033_3 1116375.VEJY3_10265 5.31e-219 606.0 COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,1RNXV@1236|Gammaproteobacteria,1XT64@135623|Vibrionales 135623|Vibrionales F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) trpD GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 ko:K00766 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R01073 RC00440 ko00000,ko00001,ko00002,ko01000 - - - Glycos_trans_3N,Glycos_transf_3 k141_9033_4 1116375.VEJY3_10270 0.0 873.0 COG0134@1|root,COG0135@1|root,COG0134@2|Bacteria,COG0135@2|Bacteria,1MW5K@1224|Proteobacteria,1RNYH@1236|Gammaproteobacteria,1XSS7@135623|Vibrionales 135623|Vibrionales E Belongs to the TrpC family trpC GO:0000162,GO:0003674,GO:0003824,GO:0004425,GO:0004640,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.48,5.3.1.24 ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03508,R03509 RC00944,RC00945 ko00000,ko00001,ko00002,ko01000 - - - IGPS,PRAI k141_9033_5 1116375.VEJY3_10275 5.9e-278 761.0 COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,1RP4D@1236|Gammaproteobacteria,1XT49@135623|Vibrionales 135623|Vibrionales E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine trpB GO:0000162,GO:0003674,GO:0003824,GO:0004834,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - PALP k141_10175_1 218284.CCDN010000005_gene3188 2.58e-25 103.0 COG4585@1|root,COG4585@2|Bacteria,1TPDG@1239|Firmicutes,4HC7E@91061|Bacilli,1ZB48@1386|Bacillus 91061|Bacilli T Histidine kinase - - 2.7.13.3 ko:K11617 ko02020,map02020 M00481,M00754 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA_3 k141_10175_2 218284.CCDN010000005_gene3187 1.22e-104 311.0 COG4758@1|root,COG4758@2|Bacteria,1TSDR@1239|Firmicutes,4HCRP@91061|Bacilli,1ZE5M@1386|Bacillus 91061|Bacilli S Cell wall-active antibiotics response 4TMS YvqF - - - ko:K11622 ko02020,map02020 - - - ko00000,ko00001 - - - DUF2154 k141_35059_1 1231057.AMGD01000091_gene1654 2.77e-15 73.6 COG1131@1|root,COG1131@2|Bacteria,1TQHS@1239|Firmicutes,4HC34@91061|Bacilli,26DZX@186818|Planococcaceae 91061|Bacilli V ABC transporter, ATP-binding protein - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 k141_35059_2 218284.CCDN010000001_gene1691 3.66e-70 217.0 COG1309@1|root,COG1309@2|Bacteria,1V3XC@1239|Firmicutes,4HMYZ@91061|Bacilli,1ZDKE@1386|Bacillus 91061|Bacilli K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N k141_689_1 218284.CCDN010000001_gene1797 2.79e-155 444.0 COG4100@1|root,COG4100@2|Bacteria,1TQ88@1239|Firmicutes,4HAF5@91061|Bacilli,1ZAXI@1386|Bacillus 91061|Bacilli P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance ynbB GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0016740,GO:0016765,GO:0016829,GO:0016846 - - - - - - - - - - Met_gamma_lyase k141_5387_1 754027.HMPREF9554_02926 1.84e-40 151.0 COG0617@1|root,COG0617@2|Bacteria,2J5ZC@203691|Spirochaetes 203691|Spirochaetes H PolyA polymerase papS - 2.7.7.72 ko:K00974 ko03013,map03013 - R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016 - - - HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2 k141_23253_1 861299.J421_3180 1.33e-82 262.0 COG0064@1|root,COG0064@2|Bacteria,1ZTCB@142182|Gemmatimonadetes 142182|Gemmatimonadetes J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatB - 6.3.5.6,6.3.5.7 ko:K02434 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - GatB_N,GatB_Yqey k141_30132_1 1042377.AFPJ01000020_gene2099 6.39e-138 400.0 COG0715@1|root,COG0715@2|Bacteria,1MWDN@1224|Proteobacteria,1RPUP@1236|Gammaproteobacteria,465AR@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components nrtC - - ko:K15576 ko00910,ko02010,map00910,map02010 M00438 - - ko00000,ko00001,ko00002,ko02000 3.A.1.16.1,3.A.1.16.2 - - NMT1_2 k141_30132_2 305900.GV64_01245 1.6e-162 464.0 COG0600@1|root,COG0600@2|Bacteria,1MU6Q@1224|Proteobacteria,1RPP1@1236|Gammaproteobacteria,1XHPK@135619|Oceanospirillales 135619|Oceanospirillales P ABC-type nitrate sulfonate bicarbonate transport system, permease component nrtB - - ko:K15577 ko00910,ko02010,map00910,map02010 M00438 - - ko00000,ko00001,ko00002,ko02000 3.A.1.16.1,3.A.1.16.2 - - BPD_transp_1 k141_30132_3 1042377.AFPJ01000020_gene2101 2.73e-80 245.0 COG1116@1|root,COG1116@2|Bacteria,1MUDV@1224|Proteobacteria,1RNEH@1236|Gammaproteobacteria,46520@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component nasD - - ko:K15578 ko00910,ko02010,map00910,map02010 M00438 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.16.1 - - ABC_tran k141_14738_1 218284.CCDN010000005_gene3423 7.98e-71 214.0 COG0316@1|root,COG0316@2|Bacteria,1V6IN@1239|Firmicutes,4HKN2@91061|Bacilli,1ZH92@1386|Bacillus 91061|Bacilli S Belongs to the HesB IscA family yutM - - ko:K13628 - - - - ko00000,ko03016 - - - Fe-S_biosyn k141_12616_1 1042377.AFPJ01000015_gene1619 1.72e-221 613.0 COG0179@1|root,COG0179@2|Bacteria,1MV0V@1224|Proteobacteria,1RNYV@1236|Gammaproteobacteria,465V2@72275|Alteromonadaceae 1236|Gammaproteobacteria Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) uptA - 3.7.1.2 ko:K16171 ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120 M00044 R01364 RC00326,RC00446 ko00000,ko00001,ko00002,ko01000 - - - FAA_hydrolase k141_12616_2 1279017.AQYJ01000027_gene1699 3.92e-121 347.0 COG0346@1|root,COG0346@2|Bacteria,1MWCV@1224|Proteobacteria,1S1HV@1236|Gammaproteobacteria,4649E@72275|Alteromonadaceae 1236|Gammaproteobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - Glyoxalase k141_13796_2 236097.ADG881_79 1.15e-17 80.1 COG1327@1|root,COG1327@2|Bacteria,1RE7V@1224|Proteobacteria,1S3P9@1236|Gammaproteobacteria,1XJKR@135619|Oceanospirillales 135619|Oceanospirillales K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes nrdR - - ko:K07738 - - - - ko00000,ko03000 - - - ATP-cone k141_7612_1 218284.CCDN010000002_gene2508 2.08e-118 351.0 COG1233@1|root,COG1233@2|Bacteria,1TQX8@1239|Firmicutes,4HBEI@91061|Bacilli,1ZBFN@1386|Bacillus 91061|Bacilli Q Flavin containing amine oxidoreductase crtP - 1.14.99.44 ko:K10210 ko00906,map00906 - R07654,R09671,R09727,R09728 RC00254,RC02089,RC02626,RC02638 ko00000,ko00001,ko01000 - - - Amino_oxidase k141_8941_1 1042377.AFPJ01000007_gene1874 1.4e-66 205.0 2E0KP@1|root,32W5Z@2|Bacteria,1N1JH@1224|Proteobacteria,1SA3K@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_35060_1 1300345.LF41_1864 2.38e-50 179.0 COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1T234@1236|Gammaproteobacteria,1X903@135614|Xanthomonadales 135614|Xanthomonadales S Adenylate cyclase - - - - - - - - - - - - TPR_16 k141_19601_1 1453501.JELR01000002_gene888 3.76e-126 385.0 COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,1RMQE@1236|Gammaproteobacteria,464C0@72275|Alteromonadaceae 1236|Gammaproteobacteria J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs rnr GO:0000175,GO:0003674,GO:0003724,GO:0003824,GO:0004386,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008408,GO:0008997,GO:0009056,GO:0009057,GO:0009266,GO:0009409,GO:0009628,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016896,GO:0017111,GO:0019222,GO:0019439,GO:0034458,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - ko:K12573 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03016,ko03019 - - - HTH_12,OB_RNB,RNB,S1 k141_25629_1 218284.CCDN010000007_gene3955 4.25e-45 155.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,1ZBYG@1386|Bacillus 91061|Bacilli I Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation mmgA GO:0003674,GO:0003824,GO:0003988,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - iYO844.BSU24170 Thiolase_C,Thiolase_N k141_25629_2 218284.CCDN010000007_gene3954 6.04e-65 215.0 COG0247@1|root,COG2181@1|root,COG0247@2|Bacteria,COG2181@2|Bacteria,1TPG1@1239|Firmicutes,4HB2J@91061|Bacilli,1ZBAJ@1386|Bacillus 91061|Bacilli C COG0247 Fe-S oxidoreductase ywjF - - - - - - - - - - - CCG,Fer4_8 k141_33850_1 315749.Bcer98_2615 8.01e-38 138.0 COG1484@1|root,COG1484@2|Bacteria,1V5FC@1239|Firmicutes,4HI1I@91061|Bacilli,1ZGRE@1386|Bacillus 91061|Bacilli L IstB-like ATP binding protein - - - ko:K02315 - - - - ko00000,ko03032 - - - IstB_IS21 k141_21930_1 1279017.AQYJ01000029_gene3489 2.12e-75 241.0 COG1228@1|root,COG1228@2|Bacteria,1MXQX@1224|Proteobacteria,1RQGS@1236|Gammaproteobacteria,465N1@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Amidohydrolase family - - - - - - - - - - - - Amidohydro_1,Amidohydro_3 k141_30133_1 42565.FP66_08845 4.72e-16 76.3 COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,1RMGZ@1236|Gammaproteobacteria,1XKY4@135619|Oceanospirillales 135619|Oceanospirillales CH D-isomer specific 2-hydroxyacid dehydrogenase - - 1.1.1.215,1.1.1.43,1.1.1.79,1.1.1.81 ko:K00032,ko:K00090 ko00030,ko00260,ko00480,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00480,map00620,map00630,map01100,map01110,map01120 - R00465,R01388,R01392,R01739,R02032,R02034 RC00001,RC00031,RC00042,RC00084 ko00000,ko00001,ko01000 - - - 2-Hacid_dh,2-Hacid_dh_C k141_30133_2 42565.FP66_08850 4.13e-76 232.0 COG0637@1|root,COG0637@2|Bacteria,1NSPA@1224|Proteobacteria,1RQET@1236|Gammaproteobacteria,1XPXU@135619|Oceanospirillales 135619|Oceanospirillales S Haloacid dehalogenase-like hydrolase - - - - - - - - - - - - HAD_2 k141_26939_2 935836.JAEL01000001_gene668 4.31e-76 241.0 COG1426@1|root,COG1426@2|Bacteria,1V1N7@1239|Firmicutes,4HKW3@91061|Bacilli,1ZDC1@1386|Bacillus 91061|Bacilli S protein conserved in bacteria ymfM - - ko:K15539 - - - - ko00000 - - - DUF4115,HTH_25 k141_32511_1 218284.CCDN010000002_gene2915 8.75e-66 216.0 COG0661@1|root,COG0661@2|Bacteria,1TPIV@1239|Firmicutes,4HBW3@91061|Bacilli,1ZBPH@1386|Bacillus 91061|Bacilli S ABC1 family ubiB - - - - - - - - - - - ABC1,APH,RIO1 k141_10178_1 218284.CCDN010000001_gene1456 1.6e-106 318.0 COG1823@1|root,COG1823@2|Bacteria,1UPUK@1239|Firmicutes,4HAJY@91061|Bacilli,1ZB7C@1386|Bacillus 91061|Bacilli U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family tcyP - - ko:K06956 - - - - ko00000 - - - SDF k141_31368_1 218284.CCDN010000002_gene2851 1.04e-113 340.0 COG1649@1|root,COG1649@2|Bacteria,1TRTG@1239|Firmicutes,4HD0M@91061|Bacilli,1ZC0H@1386|Bacillus 91061|Bacilli T Glycosyl hydrolase-like 10 yngK - - - - - - - - - - - Big_2,Cu_amine_oxidN1,GHL10 k141_11341_1 1453501.JELR01000002_gene152 5.16e-87 288.0 COG3164@1|root,COG3164@2|Bacteria,1MXWF@1224|Proteobacteria,1RNUK@1236|Gammaproteobacteria,464CY@72275|Alteromonadaceae 1236|Gammaproteobacteria S membrane yhdP GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0042597,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - - - - - - - - - - AsmA_2,DUF3971 k141_8942_1 1279017.AQYJ01000027_gene1683 2.08e-170 510.0 COG5013@1|root,COG5013@2|Bacteria,1MW9S@1224|Proteobacteria,1RQ27@1236|Gammaproteobacteria,465D5@72275|Alteromonadaceae 1236|Gammaproteobacteria C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family narG GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009898,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0031235,GO:0032991,GO:0042126,GO:0043436,GO:0043546,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0097159,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098803,GO:1901363,GO:1902494,GO:1990204,GO:2001057 1.7.5.1 ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 M00529,M00530,M00804 R00798,R01106,R09497 RC02812 ko00000,ko00001,ko00002,ko01000 5.A.3.1 - iSBO_1134.SBO_1842,iUMN146_1321.UM146_09685 Molybdopterin,Molydop_binding,Nitr_red_alph_N k141_12617_1 1042377.AFPJ01000019_gene2496 7.83e-35 121.0 COG5416@1|root,COG5416@2|Bacteria,1NGPH@1224|Proteobacteria,1SGDB@1236|Gammaproteobacteria,468XT@72275|Alteromonadaceae 1236|Gammaproteobacteria S Lipopolysaccharide assembly protein A domain - - - ko:K08992 - - - - ko00000 - - - LapA_dom k141_6532_1 1453501.JELR01000002_gene511 2.04e-57 193.0 COG2133@1|root,COG2133@2|Bacteria,1MVK5@1224|Proteobacteria,1RPE8@1236|Gammaproteobacteria,4665U@72275|Alteromonadaceae 1236|Gammaproteobacteria G COG2133 Glucose sorbosone dehydrogenases - - - - - - - - - - - - GSDH k141_6532_2 1453501.JELR01000002_gene510 4.08e-115 332.0 COG1403@1|root,COG1403@2|Bacteria,1MWEQ@1224|Proteobacteria,1S2R0@1236|Gammaproteobacteria,466G2@72275|Alteromonadaceae 1236|Gammaproteobacteria L restriction endonuclease - - - - - - - - - - - - HNH_5 k141_37320_2 1042377.AFPJ01000053_gene1518 1.97e-271 747.0 COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,1RP0C@1236|Gammaproteobacteria,465BZ@72275|Alteromonadaceae 1236|Gammaproteobacteria H Aminotransferase class-III - - 2.6.1.18 ko:K00822 ko00280,ko00410,ko00640,ko01100,map00280,map00410,map00640,map01100 - R00907,R04187 RC00008,RC00062,RC00160 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_3 k141_15969_1 218284.CCDN010000008_gene4265 1.75e-119 350.0 COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,4HAEE@91061|Bacilli,1ZBHY@1386|Bacillus 91061|Bacilli E Cysteine desulfurase iscS2 - 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - - Aminotran_5 k141_692_1 1453501.JELR01000002_gene706 2.63e-110 321.0 COG4764@1|root,COG4764@2|Bacteria,1MVRK@1224|Proteobacteria,1RQ79@1236|Gammaproteobacteria,46401@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - SLT k141_30134_1 1463841.JOIR01000006_gene4735 3.8e-17 82.8 COG3842@1|root,COG4149@1|root,COG3842@2|Bacteria,COG4149@2|Bacteria,2GJFB@201174|Actinobacteria 201174|Actinobacteria P Molybdate ABC transporter modB GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.29 ko:K02017,ko:K02018 ko02010,map02010 M00189 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.8 - - ABC_tran,BPD_transp_1,TOBE k141_30134_2 1211815.CBYP010000052_gene762 1.02e-20 90.1 COG0725@1|root,COG0725@2|Bacteria,2GMPF@201174|Actinobacteria,4ESN3@85013|Frankiales 201174|Actinobacteria P TIGRFAM molybdenum ABC transporter, periplasmic molybdate-binding protein modA GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0030288,GO:0030313,GO:0030973,GO:0031975,GO:0040007,GO:0042597,GO:0043167,GO:0043168,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704 - ko:K02020 ko02010,map02010 M00189 - - ko00000,ko00001,ko00002,ko02000 3.A.1.8 - - SBP_bac_11 k141_2870_1 1279017.AQYJ01000026_gene25 8.75e-67 213.0 COG2813@1|root,COG2813@2|Bacteria,1MXE9@1224|Proteobacteria,1RQCH@1236|Gammaproteobacteria,466JK@72275|Alteromonadaceae 1236|Gammaproteobacteria J Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle rsmC GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052914,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.172 ko:K00564 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - MTS,MTS_N k141_2870_2 1279017.AQYJ01000026_gene26 3.99e-72 220.0 2EKB9@1|root,33E1N@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k141_11342_1 1123236.KB899376_gene800 1.11e-108 323.0 COG4325@1|root,COG4325@2|Bacteria,1MXTM@1224|Proteobacteria,1RNYZ@1236|Gammaproteobacteria,466NZ@72275|Alteromonadaceae 1236|Gammaproteobacteria S Predicted membrane protein (DUF2254) - - - - - - - - - - - - DUF2254 k141_25631_1 1122194.AUHU01000004_gene1446 1.24e-15 76.6 COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,1RPZC@1236|Gammaproteobacteria,465AN@72275|Alteromonadaceae 1236|Gammaproteobacteria J exonuclease of the beta-lactamase fold involved in RNA processing - - - ko:K07576 - - - - ko00000 - - - Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL k141_27725_1 1042377.AFPJ01000004_gene407 7.01e-93 293.0 COG4247@1|root,COG4247@2|Bacteria,1MVTA@1224|Proteobacteria,1RQXH@1236|Gammaproteobacteria,46571@72275|Alteromonadaceae 1236|Gammaproteobacteria I Phytase phy - 3.1.3.8 ko:K01083 ko00562,map00562 - R03371 RC00078 ko00000,ko00001,ko01000 - - - Phytase k141_33851_1 1279017.AQYJ01000025_gene489 4.5e-157 459.0 COG1328@1|root,COG1328@2|Bacteria,1MWMS@1224|Proteobacteria,1RZFM@1236|Gammaproteobacteria,46623@72275|Alteromonadaceae 1236|Gammaproteobacteria F COG1328 Oxygen-sensitive ribonucleoside-triphosphate reductase nrdD - 1.1.98.6 ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R11633,R11634,R11635,R11636 RC00613 ko00000,ko00001,ko00002,ko01000 - - - NRDD k141_29038_1 1136163.M565_ctg5P0936 1.29e-19 80.5 COG1734@1|root,COG1734@2|Bacteria,1NGS3@1224|Proteobacteria,1SGUS@1236|Gammaproteobacteria,1XZCD@135623|Vibrionales 135623|Vibrionales T Prokaryotic dksA/traR C4-type zinc finger - - - - - - - - - - - - zf-dskA_traR k141_29038_2 1136163.M565_ctg5P0937 9.4e-89 262.0 28P27@1|root,2ZBYB@2|Bacteria,1RAH9@1224|Proteobacteria,1S754@1236|Gammaproteobacteria,1XXP4@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF2597) - - - - - - - - - - - - DUF2597 k141_29038_3 1136163.M565_ctg5P0938 2.61e-229 636.0 28I3G@1|root,2Z878@2|Bacteria,1MXMV@1224|Proteobacteria,1RND0@1236|Gammaproteobacteria,1XUM4@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF2586) - - - - - - - - - - - - DUF2586 k141_29038_4 1136163.M565_ctg5P0939 1.08e-120 348.0 2C7MJ@1|root,32RJF@2|Bacteria,1N5AD@1224|Proteobacteria,1SBE7@1236|Gammaproteobacteria,1XX46@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - Phage_tail_S k141_29038_5 1136163.M565_ctg5P0940 5.11e-99 289.0 2E24Q@1|root,32XBS@2|Bacteria,1N6XD@1224|Proteobacteria,1SD89@1236|Gammaproteobacteria,1XY7H@135623|Vibrionales 135623|Vibrionales S P2 phage tail completion protein R (GpR) - - - - - - - - - - - - P2_Phage_GpR k141_29038_6 1454202.PPBDW_100358___1 3.03e-40 138.0 2D3AE@1|root,32TEJ@2|Bacteria,1QK25@1224|Proteobacteria,1TI4S@1236|Gammaproteobacteria,1XYDP@135623|Vibrionales 135623|Vibrionales S Phage head completion protein (GPL) - - - - - - - - - - - - Phage_GPL k141_18481_2 1279017.AQYJ01000021_gene2874 2.77e-23 90.1 2E371@1|root,32Y6T@2|Bacteria,1N8D8@1224|Proteobacteria,1SCAF@1236|Gammaproteobacteria,46954@72275|Alteromonadaceae 1236|Gammaproteobacteria S YnbE-like lipoprotein ynbE - - - - - - - - - - - Lipoprotein_19 k141_18481_3 1453501.JELR01000001_gene2833 5.09e-116 387.0 COG2911@1|root,COG2911@2|Bacteria 2|Bacteria S protein secretion - - - - - - - - - - - - DctA-YdbH,Peptidase_S74 k141_19603_1 1473546.CH76_06740 3.35e-05 52.8 COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,4H9M4@91061|Bacilli,3IWT4@400634|Lysinibacillus 91061|Bacilli S Competence protein ComE comEC - - ko:K02238 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - Competence,DUF4131,Lactamase_B k141_16001_1 218284.CCDN010000010_gene4331 2.13e-25 96.3 2BVDP@1|root,32QTK@2|Bacteria,1V9E2@1239|Firmicutes,4HJ1S@91061|Bacilli,1ZFUF@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2521) ybaK - - - - - - - - - - - DUF2521 k141_16001_2 218284.CCDN010000010_gene4330 5.38e-60 191.0 COG0860@1|root,COG0860@2|Bacteria,1TQ74@1239|Firmicutes,4HAV3@91061|Bacilli,1ZBJ8@1386|Bacillus 91061|Bacilli M n-acetylmuramoyl-L-alanine amidase cwlD GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - Amidase_3 k141_29054_1 997296.PB1_01700 2.02e-180 511.0 COG3314@1|root,COG3314@2|Bacteria,1TR0V@1239|Firmicutes,4HB55@91061|Bacilli,1ZCCT@1386|Bacillus 91061|Bacilli S Sporulation integral membrane protein YlbJ ylbJ - - - - - - - - - - - Gate k141_2886_1 218284.CCDN010000008_gene4216 3.29e-61 193.0 28Z61@1|root,2ZKYB@2|Bacteria,1W2RA@1239|Firmicutes,4HSNT@91061|Bacilli,1ZIVH@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_13826_1 218284.CCDN010000001_gene1603 2.44e-130 380.0 COG2271@1|root,COG2271@2|Bacteria,1UIWI@1239|Firmicutes,4ISUR@91061|Bacilli,1ZS6G@1386|Bacillus 91061|Bacilli G Major Facilitator Superfamily - - - ko:K08152 - - - - ko00000,ko02000 2.A.1.2 - - MFS_1 k141_17183_1 558169.AGAV01000005_gene2401 6.71e-103 305.0 COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,4HATK@91061|Bacilli 91061|Bacilli I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids fabH GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - iYO844.BSU11330 ACP_syn_III,ACP_syn_III_C k141_24304_1 42565.FP66_14370 3.96e-111 333.0 COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,1RMWS@1236|Gammaproteobacteria,1XH25@135619|Oceanospirillales 135619|Oceanospirillales F Bifunctional purine biosynthesis protein PurH purH - 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 - - - AICARFT_IMPCHas,MGS k141_6551_1 218284.CCDN010000006_gene3746 3.07e-74 248.0 COG3459@1|root,COG3459@2|Bacteria,1TVMK@1239|Firmicutes,4H9ZP@91061|Bacilli,1ZF4F@1386|Bacillus 91061|Bacilli G Glycosyl hydrolase 36 superfamily, catalytic domain chvB1 - 2.4.1.20,2.4.1.333 ko:K00702,ko:K13688,ko:K21298 ko00500,ko01100,map00500,map01100 - R00952 RC00049 ko00000,ko00001,ko01000,ko01003 - GH94,GT36,GT84 - Glyco_hydro_36,Glyco_transf_36 k141_1673_1 218284.CCDN010000001_gene1912 7.82e-201 572.0 COG1298@1|root,COG1298@2|Bacteria,1TQBM@1239|Firmicutes,4H9XU@91061|Bacilli,1ZBID@1386|Bacillus 91061|Bacilli N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin flhA - - ko:K02400 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 - - FHIPEP k141_12638_2 1121929.KB898667_gene3775 1.21e-56 187.0 28I0M@1|root,2ZATW@2|Bacteria,1UZIU@1239|Firmicutes,4HCZK@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF3231) - - - - - - - - - - - - DUF3231 k141_10211_1 1005995.GTPT_1876 2.96e-38 129.0 COG2963@1|root,COG2963@2|Bacteria,1MZ3D@1224|Proteobacteria,1S6K6@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Transposase - - - ko:K07497 - - - - ko00000 - - - HTH_Tnp_1 k141_10211_2 443152.MDG893_09025 5.07e-88 265.0 COG2801@1|root,COG2801@2|Bacteria,1MVN5@1224|Proteobacteria,1RR8F@1236|Gammaproteobacteria,466E0@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG2801 Transposase and inactivated derivatives - - - ko:K07497 - - - - ko00000 - - - HTH_21,rve,rve_3 k141_10211_3 1219072.VHA01S_074_00150 7.5e-58 188.0 COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,1RMAQ@1236|Gammaproteobacteria,1XVPF@135623|Vibrionales 135623|Vibrionales L COG3547 Transposase and inactivated derivatives - - - - - - - - - - - - DEDD_Tnp_IS110,Transposase_20 k141_19634_1 1453501.JELR01000002_gene746 9.7e-230 642.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPN9@1236|Gammaproteobacteria,464QS@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0488 ATPase components of ABC transporters with duplicated ATPase domains ybiT - - - - - - - - - - - ABC_tran,ABC_tran_Xtn k141_14760_1 682795.AciX8_0742 9.55e-24 100.0 COG1691@1|root,COG1691@2|Bacteria,3Y3BX@57723|Acidobacteria,2JI0G@204432|Acidobacteriia 204432|Acidobacteriia S AIR carboxylase - - - ko:K06898 - - - - ko00000 - - - AIRC k141_33881_1 218284.CCDN010000001_gene1127 1.21e-117 338.0 COG4347@1|root,COG4347@2|Bacteria,1V1NI@1239|Firmicutes,4HFTW@91061|Bacilli,1ZFJF@1386|Bacillus 91061|Bacilli S membrane ypjA - - - - - - - - - - - DUF1405 k141_33881_2 218284.CCDN010000001_gene1128 2.74e-46 155.0 28RMR@1|root,2ZE0H@2|Bacteria,1V1HS@1239|Firmicutes,4HFRG@91061|Bacilli,1ZANV@1386|Bacillus 91061|Bacilli S sporulation protein ypjB - - - - - - - - - - - Spore_YpjB k141_710_1 1123405.AUMM01000009_gene1170 2.39e-12 67.0 COG2145@1|root,COG2145@2|Bacteria,1V1R6@1239|Firmicutes,4HFTJ@91061|Bacilli,26NWW@186821|Sporolactobacillaceae 91061|Bacilli H Hydroxyethylthiazole kinase family thiM GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008972,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.50 ko:K00878 ko00730,ko01100,map00730,map01100 M00127 R04448 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - HK k141_21958_1 218284.CCDN010000001_gene577 4.14e-217 610.0 COG1053@1|root,COG1053@2|Bacteria,1TPAR@1239|Firmicutes,4HBVG@91061|Bacilli,1ZBRD@1386|Bacillus 91061|Bacilli C succinate dehydrogenase sdhA GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0022900,GO:0044237,GO:0045333,GO:0055114 1.3.5.1,1.3.5.4 ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS05640 FAD_binding_2,Succ_DH_flav_C k141_8966_1 1121936.AUHI01000006_gene1982 2.24e-32 120.0 COG3764@1|root,COG3764@2|Bacteria,1V79B@1239|Firmicutes,4HJ8C@91061|Bacilli 91061|Bacilli M COG3764 Sortase (surface protein transpeptidase) - - - - - - - - - - - - Sortase k141_35078_1 1042377.AFPJ01000015_gene1624 5.62e-108 316.0 COG2186@1|root,COG2186@2|Bacteria,1MY1K@1224|Proteobacteria,1RMUE@1236|Gammaproteobacteria,466HJ@72275|Alteromonadaceae 1236|Gammaproteobacteria K transcriptional - - - - - - - - - - - - FCD,GntR k141_1674_1 218284.CCDN010000001_gene1904 3.19e-98 290.0 COG1191@1|root,COG1191@2|Bacteria,1TP9K@1239|Firmicutes,4HCJV@91061|Bacilli,1ZAPF@1386|Bacillus 91061|Bacilli K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released sigD - - ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 - - - ko00000,ko00001,ko02035,ko03021 - - - Sigma70_r2,Sigma70_r3,Sigma70_r4 k141_26963_1 218284.CCDN010000002_gene2248 8.96e-176 504.0 2BW99@1|root,2Z7PD@2|Bacteria,1TQFA@1239|Firmicutes,4HC1J@91061|Bacilli,1ZC3Q@1386|Bacillus 91061|Bacilli S Psort location CytoplasmicMembrane, score XK27_11280 - - - - - - - - - - - - k141_37348_1 1219076.N646_1633 3.21e-211 608.0 COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,1RN05@1236|Gammaproteobacteria,1XU3E@135623|Vibrionales 135623|Vibrionales S Insulinase (Peptidase family M16) - - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C k141_37348_2 1219076.N646_1634 8.42e-100 290.0 COG1238@1|root,COG1238@2|Bacteria,1RHUV@1224|Proteobacteria,1SCPK@1236|Gammaproteobacteria,1Y27G@135623|Vibrionales 135623|Vibrionales S SNARE associated Golgi protein - - - - - - - - - - - - SNARE_assoc k141_37348_3 1116375.VEJY3_13120 4.24e-201 560.0 COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,1RV93@1236|Gammaproteobacteria,1XTAN@135623|Vibrionales 135623|Vibrionales C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - 1.6.5.5 ko:K00344 - - - - ko00000,ko01000 - - - ADH_N,ADH_zinc_N_2 k141_37348_4 223926.28807541 9.84e-260 713.0 COG1883@1|root,COG1883@2|Bacteria,1MV0G@1224|Proteobacteria,1RP3W@1236|Gammaproteobacteria,1XTU0@135623|Vibrionales 135623|Vibrionales C Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit oadB - 4.1.1.3 ko:K01572 ko00620,ko01100,map00620,map01100 - R00217 RC00040 ko00000,ko00001,ko01000,ko02000 3.B.1.1.1 - - OAD_beta k141_37348_5 223926.28807542 0.0 1033.0 COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,1QTTG@1224|Proteobacteria,1RNG6@1236|Gammaproteobacteria,1XT1B@135623|Vibrionales 135623|Vibrionales CI oxaloacetate oadA - 4.1.1.3 ko:K01571 ko00620,ko01100,map00620,map01100 - R00217 RC00040 ko00000,ko00001,ko01000,ko02000 3.B.1.1.1 - - Biotin_lipoyl,HMGL-like,PYC_OADA k141_37348_6 1219076.N646_1638 4.61e-38 129.0 COG3630@1|root,COG3630@2|Bacteria,1NHYS@1224|Proteobacteria,1SG6X@1236|Gammaproteobacteria,1XYD5@135623|Vibrionales 135623|Vibrionales C Lyase and sodium transporter oadG GO:0003674,GO:0003824,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008948,GO:0015672,GO:0016829,GO:0016830,GO:0016831,GO:0030001,GO:0051179,GO:0051234 4.1.1.3 ko:K01573 ko00620,ko01100,map00620,map01100 - R00217 RC00040 ko00000,ko00001,ko01000,ko02000 3.B.1.1.1 - - OAD_gamma k141_37348_7 1219076.N646_1514 1.31e-27 105.0 COG2197@1|root,COG2197@2|Bacteria,1NXKF@1224|Proteobacteria,1RWZE@1236|Gammaproteobacteria,1XW9X@135623|Vibrionales 135623|Vibrionales K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - ko:K20918 ko05111,map05111 - - - ko00000,ko00001,ko03000 - - - GerE k141_711_1 1453501.JELR01000001_gene3263 7.87e-112 342.0 COG3590@1|root,COG3590@2|Bacteria,1MVNQ@1224|Proteobacteria,1RNNA@1236|Gammaproteobacteria,464DA@72275|Alteromonadaceae 1236|Gammaproteobacteria O Peptidase, M13 pepO - 3.4.24.71 ko:K01415,ko:K07386 - - - - ko00000,ko01000,ko01002,ko04147 - - - Peptidase_M13,Peptidase_M13_N k141_5423_1 218284.CCDN010000001_gene279 4.44e-24 97.4 COG1670@1|root,COG1670@2|Bacteria,1V3EY@1239|Firmicutes,4HGKG@91061|Bacilli,1ZG8B@1386|Bacillus 91061|Bacilli J Benzoate transporter - - - - - - - - - - - - Acetyltransf_1 k141_5423_2 218284.CCDN010000001_gene278 1.88e-132 384.0 COG4948@1|root,COG4948@2|Bacteria,1TQMS@1239|Firmicutes,4HCY5@91061|Bacilli,1ZC5Y@1386|Bacillus 91061|Bacilli M Belongs to the mandelate racemase muconate lactonizing enzyme family - - - - - - - - - - - - MR_MLE_C,MR_MLE_N k141_11381_1 218284.CCDN010000005_gene3353 4.92e-109 343.0 COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,4HAFP@91061|Bacilli,1ZBJ3@1386|Bacillus 91061|Bacilli V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran k141_16004_1 1353537.TP2_12530 9.35e-50 169.0 COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,2TRPK@28211|Alphaproteobacteria,2XMC9@285107|Thioclava 28211|Alphaproteobacteria E Catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate aatA - 2.6.1.1 ko:K00812 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 - R00355,R00694,R00734,R00896,R02433,R02619,R05052 RC00006 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 k141_909_5 1453501.JELR01000001_gene2982 2.19e-160 461.0 COG2829@1|root,COG2829@2|Bacteria,1PC8I@1224|Proteobacteria,1RMJH@1236|Gammaproteobacteria,4672V@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG2829 Outer membrane phospholipase A pldA - 3.1.1.32,3.1.1.4 ko:K01058 ko00564,ko00565,ko00590,ko00591,ko00592,ko01100,ko01110,map00564,map00565,map00590,map00591,map00592,map01100,map01110 - R01315,R01316,R01317,R02053,R02054,R04034,R07064,R07379,R07387,R07859,R07860 RC00020,RC00037,RC00041,RC00094 ko00000,ko00001,ko01000 - - - PLA1 k141_909_7 1279017.AQYJ01000024_gene951 5.39e-169 492.0 COG1982@1|root,COG1982@2|Bacteria,1MWK4@1224|Proteobacteria,1RMVF@1236|Gammaproteobacteria,464W7@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG1982 Arginine lysine ornithine decarboxylases - - 4.1.1.19 ko:K01584,ko:K01585 ko00330,ko01100,map00330,map01100 M00133 R00566 RC00299 ko00000,ko00001,ko00002,ko01000 - - - OKR_DC_1,OKR_DC_1_C k141_35371_1 218284.CCDN010000002_gene2636 1.86e-51 173.0 COG0860@1|root,COG0860@2|Bacteria,1TSFS@1239|Firmicutes,4HUYF@91061|Bacilli,1ZGIG@1386|Bacillus 91061|Bacilli M Stage II sporulation protein P (SpoIIP) - - - ko:K06385 - - - - ko00000 - - - SpoIIP k141_23601_1 305900.GV64_11860 1.39e-17 80.1 COG1347@1|root,COG1347@2|Bacteria,1MUZR@1224|Proteobacteria,1RNFE@1236|Gammaproteobacteria,1XHE7@135619|Oceanospirillales 135619|Oceanospirillales C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol nqrD - 1.6.5.8 ko:K00349 - - - - ko00000,ko01000 - - - Rnf-Nqr k141_23601_2 344747.PM8797T_12021 1.53e-41 142.0 COG2209@1|root,COG2209@2|Bacteria,2IYP6@203682|Planctomycetes 203682|Planctomycetes C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol nqrE - 1.6.5.8 ko:K00350 - - - - ko00000,ko01000 - - - Rnf-Nqr k141_24623_1 42565.FP66_10375 3.19e-111 320.0 COG5342@1|root,COG5342@2|Bacteria,1Q3SA@1224|Proteobacteria,1S9HS@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Invasion associated locus B (IalB) protein - - - - - - - - - - - - IalB k141_7908_1 218284.CCDN010000007_gene3874 3.58e-86 261.0 COG0714@1|root,COG0714@2|Bacteria,1V1P5@1239|Firmicutes,4HG3W@91061|Bacilli,1ZBKT@1386|Bacillus 91061|Bacilli S ATPase family associated with various cellular activities (AAA) gvpN - - - - - - - - - - - AAA_5 k141_7908_2 218284.CCDN010000007_gene3875 4.59e-25 99.4 COG0154@1|root,COG0154@2|Bacteria,1UZ2V@1239|Firmicutes,4HE70@91061|Bacilli,1ZDE6@1386|Bacillus 91061|Bacilli J Gas vesicle synthesis protein GvpL/GvpF - - - - - - - - - - - - GvpL_GvpF k141_4330_1 158190.SpiGrapes_1095 1.14e-71 231.0 COG1070@1|root,COG1070@2|Bacteria,2J5M1@203691|Spirochaetes 203691|Spirochaetes G PFAM FGGY family of carbohydrate kinases, N-terminal domain xylB - 2.7.1.17 ko:K00854 ko00040,ko01100,map00040,map01100 M00014 R01639 RC00002,RC00538 ko00000,ko00001,ko00002,ko01000 - - - FGGY_C,FGGY_N k141_18852_1 698769.JFBD01000019_gene2003 1.11e-39 145.0 COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,4H9Y8@91061|Bacilli,4C5ET@84406|Virgibacillus 91061|Bacilli L DnaB-like helicase C terminal domain - - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k141_36299_1 1294265.JCM21738_4461 1.24e-08 53.9 COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,4H9XC@91061|Bacilli,1ZHTN@1386|Bacillus 91061|Bacilli J tRNA synthetases class II (A) alaS GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DHHA1,tRNA-synt_2c,tRNA_SAD k141_36299_2 1294265.JCM21738_4460 1.89e-13 68.9 COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,4H9SR@91061|Bacilli,1ZBGE@1386|Bacillus 91061|Bacilli S AI-2E family transporter yrrI GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - - - - - - - - - - AI-2E_transport k141_6832_1 1453501.JELR01000001_gene2684 3.08e-86 263.0 COG0412@1|root,COG0412@2|Bacteria,1NRB4@1224|Proteobacteria,1SBI0@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q Dienelactone hydrolase - - 3.1.1.45 ko:K01061 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 - R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222 RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 - - - DLH k141_6832_2 1279017.AQYJ01000024_gene1161 9.4e-103 303.0 COG2818@1|root,COG2818@2|Bacteria,1R3WB@1224|Proteobacteria,1RSAH@1236|Gammaproteobacteria,46502@72275|Alteromonadaceae 1236|Gammaproteobacteria L 3-methyladenine DNA glycosylase IV02_03670 - - - - - - - - - - - Adenine_glyco k141_910_1 218284.CCDN010000001_gene1798 1.44e-70 224.0 COG2262@1|root,COG2262@2|Bacteria,1TNZB@1239|Firmicutes,4HACA@91061|Bacilli,1ZBT6@1386|Bacillus 91061|Bacilli S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis hflX - - ko:K03665 - - - - ko00000,ko03009 - - - GTP-bdg_M,GTP-bdg_N,MMR_HSR1 k141_32803_1 1116375.VEJY3_16361 3.46e-34 119.0 COG3171@1|root,COG3171@2|Bacteria,1N8GZ@1224|Proteobacteria,1SZV9@1236|Gammaproteobacteria,1XXWD@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria - - - ko:K09923 - - - - ko00000 - - - DUF469 k141_15011_1 1042377.AFPJ01000004_gene406 2e-182 535.0 COG1629@1|root,COG4771@2|Bacteria,1MUWN@1224|Proteobacteria,1RN1E@1236|Gammaproteobacteria,464FG@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec k141_15011_2 1042377.AFPJ01000004_gene405 1.03e-275 770.0 COG3211@1|root,COG3211@2|Bacteria,1MU8T@1224|Proteobacteria,1RMIU@1236|Gammaproteobacteria,464FZ@72275|Alteromonadaceae 1236|Gammaproteobacteria S Bacterial protein of unknown function (DUF839) uxpB - - ko:K07093 - - - - ko00000 - - - DUF839 k141_30319_1 199306.XP_003066086.1 2.16e-07 56.6 KOG3360@1|root,KOG3360@2759|Eukaryota,39JPV@33154|Opisthokonta,3Q41U@4751|Fungi,3RM68@4890|Ascomycota,20UDN@147545|Eurotiomycetes,3B461@33183|Onygenales,3FPH8@34383|Onygenales incertae sedis 4751|Fungi O Acylphosphatase - - 3.6.1.7 ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 - R00317,R01421,R01515 RC00043 ko00000,ko00001,ko01000 - - - Acylphosphatase k141_30319_2 1165094.RINTHH_13060 1.17e-29 132.0 COG0189@1|root,COG0769@1|root,COG0189@2|Bacteria,COG0769@2|Bacteria,1G141@1117|Cyanobacteria,1HIDU@1161|Nostocales 1117|Cyanobacteria HJM Mur ligase family, glutamate ligase domain cphA - 6.3.2.29,6.3.2.30 ko:K03802 - - - - ko00000,ko01000 - - - Mur_ligase_C,Mur_ligase_M,RimK k141_24624_2 1042377.AFPJ01000036_gene1273 6.66e-98 285.0 COG1047@1|root,COG1047@2|Bacteria,1RD35@1224|Proteobacteria,1S3QR@1236|Gammaproteobacteria,467AX@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG1047 FKBP-type peptidyl-prolyl cis-trans isomerases 2 slyD - 5.2.1.8 ko:K03775 - - - - ko00000,ko01000,ko03110 - - - FKBP_C k141_17379_1 574375.BAGA_09565 5.77e-42 156.0 28UBU@1|root,2ZGH7@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k141_23603_1 218284.CCDN010000001_gene1513 1.29e-98 308.0 COG1112@1|root,COG1112@2|Bacteria,1UNF1@1239|Firmicutes,4IPKF@91061|Bacilli,1ZDR8@1386|Bacillus 91061|Bacilli L COG1112 Superfamily I DNA and RNA helicases and helicase subunits - - - - - - - - - - - - AAA_11,AAA_12 k141_11650_1 42565.FP66_06595 4.33e-112 332.0 COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,1RNJV@1236|Gammaproteobacteria,1XHSE@135619|Oceanospirillales 135619|Oceanospirillales U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently secY - - ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5 - - SecY k141_14174_2 218284.CCDN010000001_gene50 1.55e-54 171.0 COG2052@1|root,COG2052@2|Bacteria,1VA40@1239|Firmicutes,4HKDP@91061|Bacilli,1ZHVQ@1386|Bacillus 91061|Bacilli S Belongs to the UPF0296 family ylzA - - ko:K09777 - - - - ko00000 - - - DUF370 k141_14174_3 218284.CCDN010000001_gene51 5.44e-53 174.0 COG1561@1|root,COG1561@2|Bacteria,1TQHJ@1239|Firmicutes,4HAK9@91061|Bacilli,1ZCGE@1386|Bacillus 91061|Bacilli S stress-induced protein yloC - - - - - - - - - - - DUF1732,YicC_N k141_9267_2 1453501.JELR01000005_gene1713 3.01e-56 177.0 COG0222@1|root,COG0222@2|Bacteria,1RGU4@1224|Proteobacteria,1S5V7@1236|Gammaproteobacteria,46787@72275|Alteromonadaceae 1236|Gammaproteobacteria J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation rplL GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042802,GO:0042803,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0046983,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02935 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L12,Ribosomal_L12_N k141_9267_3 1453501.JELR01000005_gene1712 3.05e-96 282.0 COG0244@1|root,COG0244@2|Bacteria,1RAN5@1224|Proteobacteria,1S286@1236|Gammaproteobacteria,46765@72275|Alteromonadaceae 1236|Gammaproteobacteria J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors rplJ GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0017148,GO:0019222,GO:0019538,GO:0022625,GO:0022626,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - ko:K02864 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L10 k141_911_1 1131730.BAVI_01110 8.88e-41 135.0 2EJ4H@1|root,33CVR@2|Bacteria,1VMIU@1239|Firmicutes,4HP24@91061|Bacilli,1ZJ5B@1386|Bacillus 91061|Bacilli S Peptide ABC transporter permease yabK - - - - - - - - - - - DUF2757 k141_911_2 1294265.JCM21738_4365 4.35e-28 105.0 COG0193@1|root,COG0193@2|Bacteria,1V3NB@1239|Firmicutes,4HH2Z@91061|Bacilli,1ZC7I@1386|Bacillus 91061|Bacilli J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis pth GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 ko:K01056 - - - - ko00000,ko01000,ko03012 - - - Pept_tRNA_hydro k141_6833_1 491952.Mar181_2390 1.59e-147 441.0 COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RN01@1236|Gammaproteobacteria,1XIAS@135619|Oceanospirillales 135619|Oceanospirillales S of the RND superfamily - - - ko:K07003 - - - - ko00000 - - - MMPL k141_5704_1 1385511.N783_03130 6.59e-24 93.2 COG5460@1|root,COG5460@2|Bacteria,1VG76@1239|Firmicutes,4HNYG@91061|Bacilli,2YAY7@289201|Pontibacillus 91061|Bacilli S Uncharacterized conserved protein (DUF2164) - - - - - - - - - - - - DUF2164 k141_35373_1 1294265.JCM21738_1815 1.08e-119 352.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,1ZBIW@1386|Bacillus 91061|Bacilli V COG1132 ABC-type multidrug transport system, ATPase and permease components yfiC3 - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran k141_3116_2 218284.CCDN010000002_gene2381 5.95e-24 91.7 2DB6C@1|root,32TWU@2|Bacteria,1VC4Z@1239|Firmicutes,4HKEX@91061|Bacilli,1ZGUZ@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3243) - - - - - - - - - - - - DUF3243 k141_18854_1 218284.CCDN010000001_gene1039 2.06e-84 259.0 COG1015@1|root,COG1015@2|Bacteria,1TP70@1239|Firmicutes,4H9RU@91061|Bacilli,1ZBG0@1386|Bacillus 91061|Bacilli G Phosphotransfer between the C1 and C5 carbon atoms of pentose deoB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008973,GO:0009987,GO:0016853,GO:0016866,GO:0016868,GO:0034641,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360 5.4.2.7 ko:K01839 ko00030,ko00230,map00030,map00230 - R01057,R02749 RC00408 ko00000,ko00001,ko01000 - - - Metalloenzyme k141_18854_2 218284.CCDN010000001_gene1040 1.57e-120 348.0 COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,4HABP@91061|Bacilli,1ZBKZ@1386|Bacillus 91061|Bacilli F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate punA - 2.4.2.1,2.4.2.28 ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 M00034 R01402,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244 RC00033,RC00063,RC00122,RC02819 ko00000,ko00001,ko00002,ko01000 - - - PNP_UDP_1 k141_9268_2 1279017.AQYJ01000027_gene1833 8.62e-44 154.0 COG0508@1|root,COG0508@2|Bacteria,1MVDC@1224|Proteobacteria,1RQ9Y@1236|Gammaproteobacteria,4657Y@72275|Alteromonadaceae 1236|Gammaproteobacteria C 2-oxoacid dehydrogenases acyltransferase (catalytic domain) pdhC - 2.3.1.12,2.3.1.168 ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 M00036,M00307 R00209,R02569,R02662,R03174,R04097,R10998 RC00004,RC02727,RC02742,RC02857,RC02870 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding k141_16243_1 1279017.AQYJ01000028_gene2457 1.7e-23 98.6 COG0026@1|root,COG0026@2|Bacteria,1MU70@1224|Proteobacteria,1RQEI@1236|Gammaproteobacteria,46573@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) purK GO:0000166,GO:0003674,GO:0003824,GO:0004638,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0016874,GO:0016879,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034028,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.4.18 ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07404 RC01927 ko00000,ko00001,ko00002,ko01000 - - iECUMN_1333.ECUMN_0562,iYL1228.KPN_00477 ATP-grasp k141_16243_2 1042377.AFPJ01000053_gene1499 8.66e-48 156.0 COG1320@1|root,COG1320@2|Bacteria 2|Bacteria P monovalent cation:proton antiporter activity mrpG - - ko:K05571 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - PhaG_MnhG_YufB k141_16243_3 1042377.AFPJ01000053_gene1500 5.01e-44 146.0 COG2212@1|root,COG2212@2|Bacteria 2|Bacteria P antiporter activity mnhF - - ko:K05570 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - MrpF_PhaF k141_16243_4 357808.RoseRS_2098 4.83e-35 126.0 COG1863@1|root,COG1863@2|Bacteria,2G72R@200795|Chloroflexi,377GU@32061|Chloroflexia 32061|Chloroflexia P PFAM cation antiporter - - - ko:K05569 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - MNHE k141_16243_5 1479238.JQMZ01000001_gene1601 0.000714 42.4 COG0651@1|root,COG0651@2|Bacteria,1MURB@1224|Proteobacteria,2TRQ2@28211|Alphaproteobacteria,43X46@69657|Hyphomonadaceae 28211|Alphaproteobacteria CP COG0651 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit - - - ko:K05568 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - Proton_antipo_M k141_12870_1 218284.CCDN010000005_gene3493 3.82e-57 184.0 COG1349@1|root,COG1349@2|Bacteria,1TSF8@1239|Firmicutes,4HDT9@91061|Bacilli,1ZBIR@1386|Bacillus 91061|Bacilli K Transcriptional regulator fruR - - ko:K03436 - - - - ko00000,ko03000 - - - DeoRC,HTH_DeoR k141_5705_1 1453501.JELR01000002_gene427 9.64e-131 379.0 COG2232@1|root,COG2232@2|Bacteria,1QW2V@1224|Proteobacteria,1T2QR@1236|Gammaproteobacteria 1236|Gammaproteobacteria S ATP-grasp domain - - - - - - - - - - - - ATP-grasp_3 k141_36301_1 264732.Moth_0703 8.3e-69 221.0 COG0182@1|root,COG0182@2|Bacteria,1TPDK@1239|Firmicutes,249C5@186801|Clostridia,42I51@68295|Thermoanaerobacterales 186801|Clostridia J Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) mtnA - 5.3.1.23 ko:K08963 ko00270,ko01100,map00270,map01100 M00034 R04420 RC01151 ko00000,ko00001,ko00002,ko01000 - - - IF-2B k141_7932_1 1385513.N780_15100 2.06e-26 110.0 COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,4HAHY@91061|Bacilli,2Y9TB@289201|Pontibacillus 91061|Bacilli L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrA - 5.99.1.3 ko:K02469 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseA_C,DNA_topoisoIV k141_23629_1 218284.CCDN010000001_gene1281 7.43e-114 342.0 COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,4HB31@91061|Bacilli,1ZARE@1386|Bacillus 91061|Bacilli EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia trpE GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.1.3.27 ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Anth_synt_I_N,Chorismate_bind k141_22285_1 218284.CCDN010000001_gene7 1.04e-74 231.0 COG0758@1|root,COG0758@2|Bacteria,1TPP7@1239|Firmicutes,4HGWM@91061|Bacilli,1ZBZ3@1386|Bacillus 91061|Bacilli LU Rossmann fold nucleotide-binding protein involved in DNA uptake dprA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0007154,GO:0008150,GO:0009292,GO:0009294,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0044424,GO:0044464,GO:0044764,GO:0050896,GO:0051704,GO:0051716,GO:0071496 - ko:K04096 - - - - ko00000 - - - DNA_processg_A k141_22285_2 218284.CCDN010000001_gene8 1.09e-141 404.0 COG0074@1|root,COG0074@2|Bacteria,1TPIT@1239|Firmicutes,4HA2J@91061|Bacilli,1ZCHE@1386|Bacillus 91061|Bacilli C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit sucD - 6.2.1.5 ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU16100 CoA_binding,Ligase_CoA k141_29303_1 218284.CCDN010000001_gene1262 6.37e-148 420.0 COG4667@1|root,COG4667@2|Bacteria,1TQ9W@1239|Firmicutes,4HCHJ@91061|Bacilli,1ZD2S@1386|Bacillus 91061|Bacilli S Patatin-like phospholipase - - - - - - - - - - - - Patatin k141_938_1 1453501.JELR01000002_gene1518 1.83e-45 164.0 COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,1RPF7@1236|Gammaproteobacteria,46550@72275|Alteromonadaceae 1236|Gammaproteobacteria CO Thiol disulfide interchange protein dsbD - 1.8.1.8 ko:K04084 - - - - ko00000,ko01000,ko03110 5.A.1.1 - - DsbC,DsbD,Thioredoxin_7 k141_11666_4 1279017.AQYJ01000029_gene3409 9.72e-219 615.0 COG0114@1|root,COG0114@2|Bacteria,1MUQI@1224|Proteobacteria,1RNUS@1236|Gammaproteobacteria,464A2@72275|Alteromonadaceae 1236|Gammaproteobacteria C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate fumC - 4.2.1.2 ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 M00009,M00011,M00173,M00376 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - - FumaraseC_C,Lyase_1 k141_27305_1 218284.CCDN010000006_gene3514 4.91e-138 413.0 COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1TR8J@1239|Firmicutes,4H9XN@91061|Bacilli,1ZATV@1386|Bacillus 91061|Bacilli I 3-hydroxyacyl-CoA dehydrogenase fadN - 1.1.1.35 ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 M00087 R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU32840 3HCDH,3HCDH_N,ECH_1 k141_3137_1 1123236.KB899386_gene1868 2.98e-12 65.5 COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,1RN7V@1236|Gammaproteobacteria,464MZ@72275|Alteromonadaceae 1236|Gammaproteobacteria S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis hflX GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003924,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006417,GO:0006464,GO:0006468,GO:0006518,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006996,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018105,GO:0018193,GO:0018209,GO:0019001,GO:0019222,GO:0019538,GO:0019843,GO:0022411,GO:0030554,GO:0031323,GO:0031326,GO:0032268,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0032790,GO:0032984,GO:0032988,GO:0034248,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0036211,GO:0036289,GO:0043021,GO:0043022,GO:0043023,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0071826,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:2000112 - ko:K03665 - - - - ko00000,ko03009 - - - GTP-bdg_M,GTP-bdg_N,MMR_HSR1 k141_3137_2 1123236.KB899386_gene1867 1.09e-49 158.0 COG1923@1|root,COG1923@2|Bacteria,1MZM1@1224|Proteobacteria,1S8W0@1236|Gammaproteobacteria,467WJ@72275|Alteromonadaceae 1236|Gammaproteobacteria J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs hfq GO:0003674,GO:0003676,GO:0003677,GO:0003681,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006417,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016246,GO:0016441,GO:0016458,GO:0017148,GO:0019222,GO:0022607,GO:0022613,GO:0022618,GO:0030423,GO:0031047,GO:0031123,GO:0031124,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032268,GO:0032269,GO:0032270,GO:0034248,GO:0034249,GO:0034250,GO:0034622,GO:0034641,GO:0035194,GO:0040029,GO:0040033,GO:0043170,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045974,GO:0045975,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:2000112,GO:2000113 - ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 - - - ko00000,ko00001,ko03019,ko03036 - - - Hfq k141_14202_1 1453501.JELR01000001_gene3063 3.91e-38 142.0 COG0501@1|root,COG0501@2|Bacteria,1MVU4@1224|Proteobacteria,1RPJ5@1236|Gammaproteobacteria,46584@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG0501 Zn-dependent protease with chaperone function htpX - - ko:K03799 - M00743 - - ko00000,ko00002,ko01000,ko01002 - - - Peptidase_M48 k141_14202_2 1042377.AFPJ01000034_gene2352 1.25e-100 294.0 COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,1RP1N@1236|Gammaproteobacteria,464MJ@72275|Alteromonadaceae 1236|Gammaproteobacteria S LemA family lemA - - ko:K03744 - - - - ko00000 - - - LemA k141_37528_1 247634.GPB2148_877 3.23e-72 236.0 COG2015@1|root,COG2015@2|Bacteria,1MU82@1224|Proteobacteria,1RMHR@1236|Gammaproteobacteria,1J7YQ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria Q COG2015 Alkyl sulfatase and related hydrolases - - - - - - - - - - - - Alkyl_sulf_C,Alkyl_sulf_dimr,Lactamase_B k141_32821_1 1161401.ASJA01000005_gene2396 4.13e-80 247.0 COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,2TR5W@28211|Alphaproteobacteria,43WMA@69657|Hyphomonadaceae 28211|Alphaproteobacteria E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) - - 3.5.4.22,4.1.2.28,4.3.3.7 ko:K01714,ko:K21062,ko:K22397 ko00040,ko00261,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01230,map00040,map00261,map00300,map00330,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R01782,R02280,R10147 RC00307,RC00572,RC00679,RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS k141_16258_1 1469557.JSWF01000024_gene1728 1.62e-11 65.1 COG1846@1|root,COG1846@2|Bacteria,4NQ5T@976|Bacteroidetes,1I2YC@117743|Flavobacteriia 976|Bacteroidetes K transcriptional regulator - - - - - - - - - - - - MarR k141_35390_1 218284.CCDN010000006_gene3527 1.13e-159 452.0 COG0614@1|root,COG0614@2|Bacteria,1TR63@1239|Firmicutes,4HB8N@91061|Bacilli,1ZCYN@1386|Bacillus 91061|Bacilli P ABC transporter substrate-binding protein yfiY - - ko:K02016 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - Peripla_BP_2 k141_36321_1 1196031.ALEG01000034_gene5348 3.79e-87 271.0 COG0659@1|root,COG0659@2|Bacteria,1TPI4@1239|Firmicutes,4H9V4@91061|Bacilli,1ZCKC@1386|Bacillus 91061|Bacilli P COG0659 Sulfate permease and related transporters (MFS superfamily) ybaR - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - STAS,Sulfate_transp k141_19903_1 666686.B1NLA3E_12390 2.57e-168 497.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,4HBU2@91061|Bacilli,1ZCZH@1386|Bacillus 91061|Bacilli G Belongs to the PEP-utilizing enzyme family ppdK - 2.7.9.1 ko:K01006 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 M00169,M00171,M00172,M00173 R00206 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - PEP-utilizers,PEP-utilizers_C,PPDK_N k141_27951_1 42565.FP66_15005 3.94e-100 290.0 COG3565@1|root,COG3565@2|Bacteria,1RD7C@1224|Proteobacteria,1S6SD@1236|Gammaproteobacteria,1XJYN@135619|Oceanospirillales 135619|Oceanospirillales S dioxygenase of extradiol dioxygenase family - - - ko:K06991 - - - - ko00000 - - - Glyoxalase k141_23630_1 1265505.ATUG01000002_gene2452 7.13e-33 133.0 COG2866@1|root,COG2866@2|Bacteria,1N9W9@1224|Proteobacteria,433QQ@68525|delta/epsilon subdivisions,2WY7P@28221|Deltaproteobacteria 28221|Deltaproteobacteria E Zinc carboxypeptidase - - - - - - - - - - - - Peptidase_M14 k141_18889_2 1279017.AQYJ01000020_gene1237 5.53e-151 431.0 COG1226@1|root,2Z7ZD@2|Bacteria,1MXKM@1224|Proteobacteria,1RNMT@1236|Gammaproteobacteria,464C8@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1226 Kef-type K transport systems - - - ko:K08714 - - - - ko00000,ko02000 1.A.1.14 - - Ion_trans k141_14203_1 1294265.JCM21738_2359 2.14e-56 192.0 COG1595@1|root,COG1595@2|Bacteria,1U9I0@1239|Firmicutes,4IJNF@91061|Bacilli,1ZC9D@1386|Bacillus 91061|Bacilli K Domain of unknown function (DUF4179) - - - - - - - - - - - - DUF4179,Sigma70_r4,Sigma70_r4_2,zf-HC2 k141_29305_1 1453501.JELR01000001_gene2488 8.49e-88 259.0 COG0589@1|root,COG0589@2|Bacteria,1RHE6@1224|Proteobacteria,1S6AR@1236|Gammaproteobacteria,467I4@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0589 Universal stress protein UspA and related nucleotide-binding proteins uspA - - ko:K06149 - - - - ko00000 - - - Usp k141_25938_2 1280001.BAOA01000061_gene4473 4.82e-256 704.0 COG0153@1|root,COG0153@2|Bacteria,1MVQD@1224|Proteobacteria,1RQ0C@1236|Gammaproteobacteria,1XUF3@135623|Vibrionales 135623|Vibrionales F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) galK GO:0003674,GO:0003824,GO:0004335,GO:0005975,GO:0005996,GO:0006012,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019318,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046835,GO:0071704 2.7.1.6 ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00554,M00632 R01092 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko04147 - - - GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg k141_34134_1 1279017.AQYJ01000019_gene1498 2.81e-18 81.3 COG2885@1|root,COG2885@2|Bacteria,1RIG3@1224|Proteobacteria,1S5WW@1236|Gammaproteobacteria,46CH4@72275|Alteromonadaceae 1236|Gammaproteobacteria M OmpA family - - - - - - - - - - - - DUF4398,OmpA k141_34134_3 1279017.AQYJ01000019_gene1495 2.87e-128 387.0 COG0642@1|root,COG0642@2|Bacteria,1QU3Z@1224|Proteobacteria,1T311@1236|Gammaproteobacteria,46D2F@72275|Alteromonadaceae 1236|Gammaproteobacteria T Histidine kinase - - - - - - - - - - - - CBM9_1,HATPase_c,HisKA k141_11668_1 1294265.JCM21738_4812 4.29e-109 321.0 COG1744@1|root,COG1744@2|Bacteria,1TPEU@1239|Firmicutes,4HBCY@91061|Bacilli,1ZCTZ@1386|Bacillus 91061|Bacilli S ABC transporter substrate-binding protein PnrA-like - - - ko:K07335 - - - - ko00000 - - - Bmp k141_30335_1 218284.CCDN010000001_gene208 9.08e-42 144.0 COG1028@1|root,COG1028@2|Bacteria,1TR1J@1239|Firmicutes,4HAQ2@91061|Bacilli,1ZBZF@1386|Bacillus 91061|Bacilli IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - - - - - - - - - - adh_short_C2 k141_19904_1 1453501.JELR01000002_gene1196 3.07e-29 106.0 COG2261@1|root,COG2261@2|Bacteria,1N72W@1224|Proteobacteria,1S8YP@1236|Gammaproteobacteria,46BPP@72275|Alteromonadaceae 1236|Gammaproteobacteria S Transglycosylase associated protein yeaQ - - - - - - - - - - - Transgly_assoc k141_19904_2 1453501.JELR01000002_gene1197 3.03e-41 142.0 COG0451@1|root,COG0451@2|Bacteria,1MWVJ@1224|Proteobacteria,1RNDT@1236|Gammaproteobacteria,4673H@72275|Alteromonadaceae 1236|Gammaproteobacteria GM COG0451 Nucleoside-diphosphate-sugar epimerases - - - - - - - - - - - - Epimerase,NAD_binding_10,RmlD_sub_bind k141_32822_2 218284.CCDN010000004_gene3128 6.41e-16 76.6 COG0477@1|root,COG2814@2|Bacteria,1U72T@1239|Firmicutes,4HCHH@91061|Bacilli,1ZCHP@1386|Bacillus 91061|Bacilli EGP COG0477 Permeases of the major facilitator superfamily ykuC - - - - - - - - - - - MFS_1 k141_18890_1 240302.BN982_03114 4.41e-12 61.2 COG1141@1|root,COG1141@2|Bacteria,1VAC2@1239|Firmicutes,4HKG7@91061|Bacilli 91061|Bacilli C Ferredoxin fer - - ko:K05337 - - - - ko00000 - - - Fer4_13,Fer4_15 k141_18890_2 1444309.JAQG01000073_gene307 1.84e-14 73.9 2DRG2@1|root,33BJP@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k141_12878_2 1231336.L248_2353 1.72e-12 70.5 COG0558@1|root,COG0558@2|Bacteria,1V4YR@1239|Firmicutes,4HKKN@91061|Bacilli,3F90C@33958|Lactobacillaceae 91061|Bacilli I CDP-alcohol phosphatidyltransferase - - 2.7.8.41 ko:K08744 ko00564,ko01100,map00564,map01100 - R02030 RC00002,RC00017 ko00000,ko00001,ko01000 - - - CDP-OH_P_transf k141_12878_3 1279017.AQYJ01000027_gene1774 3.4e-312 855.0 COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,1RMN6@1236|Gammaproteobacteria,464EN@72275|Alteromonadaceae 1236|Gammaproteobacteria P Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA trkH GO:0003674,GO:0005215,GO:0005216,GO:0005261,GO:0005267,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015318,GO:0015672,GO:0016020,GO:0016021,GO:0022803,GO:0022838,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031224,GO:0031226,GO:0031420,GO:0034220,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0046983,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098660,GO:0098662 - ko:K03498 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - iPC815.YPO3762,iSFV_1184.SFV_3651 TrkH k141_23632_1 218284.CCDN010000006_gene3530 1.14e-79 247.0 2DH6Y@1|root,2ZYKQ@2|Bacteria,1V3RR@1239|Firmicutes,4HHKE@91061|Bacilli,1ZBHI@1386|Bacillus 91061|Bacilli S Spore germination B3/ GerAC like, C-terminal - - - ko:K06308 - - - - ko00000 - - - Spore_GerAC k141_939_1 1279017.AQYJ01000027_gene1799 4.64e-238 657.0 COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,1RMNP@1236|Gammaproteobacteria,4648R@72275|Alteromonadaceae 1236|Gammaproteobacteria L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria dnaN GO:0003674,GO:0003824,GO:0003887,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0022616,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3 k141_35392_1 1453501.JELR01000001_gene2973 3.91e-92 275.0 COG1434@1|root,COG1434@2|Bacteria,1MVW8@1224|Proteobacteria,1S92A@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Conserved Protein - - - - - - - - - - - - DUF218 k141_4351_2 218284.CCDN010000002_gene2127 1.77e-223 619.0 COG0498@1|root,COG0498@2|Bacteria,1TP25@1239|Firmicutes,4HA1F@91061|Bacilli,1ZB11@1386|Bacillus 91061|Bacilli E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine thrC GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008144,GO:0016829,GO:0016835,GO:0016838,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU32250 PALP k141_4351_3 218284.CCDN010000002_gene2126 6.67e-149 429.0 COG0460@1|root,COG0460@2|Bacteria,1TQ2H@1239|Firmicutes,4HBAP@91061|Bacilli,1ZAVJ@1386|Bacillus 91061|Bacilli E homoserine dehydrogenase hom - 1.1.1.3 ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00017,M00018 R01773,R01775 RC00087 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS06610 ACT,Homoserine_dh,NAD_binding_3 k141_14205_1 218284.CCDN010000008_gene4086 8.39e-127 362.0 COG2197@1|root,COG2197@2|Bacteria,1TRXG@1239|Firmicutes,4HA3V@91061|Bacilli,1ZB23@1386|Bacillus 91061|Bacilli KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain degU - - ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 M00478 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg k141_8021_1 1027292.HMPREF9372_3507 1.99e-22 99.8 COG2304@1|root,COG2304@2|Bacteria,1UZKX@1239|Firmicutes,4HCSC@91061|Bacilli,26FIF@186818|Planococcaceae 91061|Bacilli S von Willebrand factor type A domain - - - - - - - - - - - - VWA,VWA_2 k141_30514_1 218284.CCDN010000006_gene3583 8.93e-114 326.0 COG1376@1|root,COG1376@2|Bacteria,1V9XU@1239|Firmicutes,4HKDD@91061|Bacilli,1ZGIN@1386|Bacillus 91061|Bacilli S protein conserved in bacteria ykuD - - - - - - - - - - - LysM,YkuD k141_10598_1 314285.KT71_00345 2.84e-143 412.0 COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,1RMSS@1236|Gammaproteobacteria,1J5GB@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L Phage integrase family - - - - - - - - - - - - Phage_int_SAM_4,Phage_integrase k141_17680_1 1033734.CAET01000024_gene1135 2.85e-103 310.0 COG0385@1|root,COG0385@2|Bacteria,1TP85@1239|Firmicutes,4HB6E@91061|Bacilli,1ZQNX@1386|Bacillus 91061|Bacilli S Na -dependent transporter ybaS - - - - - - - - - - - SBF,SBF_like k141_2165_1 218284.CCDN010000008_gene4196 3.55e-39 136.0 COG1514@1|root,COG1514@2|Bacteria,1VCBK@1239|Firmicutes,4HM3V@91061|Bacilli,1ZHT8@1386|Bacillus 91061|Bacilli J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester ytlP GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 ko:K01975 - - - - ko00000,ko01000,ko03016 - - - LigT_PEase k141_8022_1 218284.CCDN010000001_gene1940 6.55e-111 333.0 COG4187@1|root,COG4187@2|Bacteria,1TQQ7@1239|Firmicutes,4HABT@91061|Bacilli,1ZCEE@1386|Bacillus 91061|Bacilli E arginine degradation protein rocB - - - - - - - - - - - Peptidase_M20 k141_34368_1 218284.CCDN010000001_gene1505 3.99e-38 132.0 COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,4HJN1@91061|Bacilli,1ZFAP@1386|Bacillus 91061|Bacilli CO COG0526 Thiol-disulfide isomerase and thioredoxins stoA - - - - - - - - - - - AhpC-TSA k141_15216_1 1380387.JADM01000002_gene2223 1.42e-43 153.0 COG3852@1|root,COG3852@2|Bacteria,1MVN6@1224|Proteobacteria,1RN15@1236|Gammaproteobacteria,1XHHE@135619|Oceanospirillales 135619|Oceanospirillales T Histidine kinase ntrB - 2.7.13.3 ko:K07708 ko02020,map02020 M00497 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS,PAS_4,PAS_8 k141_15216_2 1123261.AXDW01000011_gene572 1.68e-11 64.7 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1X3NB@135614|Xanthomonadales 135614|Xanthomonadales T Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains ntrC - - ko:K07712 ko02020,map02020 M00497 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat k141_17681_1 1453501.JELR01000002_gene473 2.3e-126 372.0 COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,1RPIW@1236|Gammaproteobacteria,46464@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Amidohydrolase family dan - 3.5.1.81,3.5.1.82 ko:K01461,ko:K06015 - - R02192 RC00064,RC00328 ko00000,ko01000 - - - Amidohydro_3 k141_29658_1 1123228.AUIH01000014_gene355 1.75e-253 707.0 COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,1RMCN@1236|Gammaproteobacteria,1XIC8@135619|Oceanospirillales 135619|Oceanospirillales P transporter antisigma-factor antagonist STAS - - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - STAS,Sulfate_transp k141_29658_2 1453501.JELR01000001_gene2196 6.19e-226 626.0 COG0722@1|root,COG0722@2|Bacteria,1MU5Q@1224|Proteobacteria,1RMAA@1236|Gammaproteobacteria,465DU@72275|Alteromonadaceae 1236|Gammaproteobacteria E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) aroF GO:0003674,GO:0003824,GO:0003849,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019438,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.54 ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_3932,iECOK1_1307.ECOK1_2946,iECS88_1305.ECS88_2787,iUMN146_1321.UM146_03705,iUTI89_1310.UTI89_C2934 DAHP_synth_1 k141_29658_3 1279017.AQYJ01000025_gene702 0.0 1601.0 COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,1RPC6@1236|Gammaproteobacteria,46518@72275|Alteromonadaceae 1236|Gammaproteobacteria L UvrD-like helicase C-terminal domain addA - - - - - - - - - - - PDDEXK_1,UvrD-helicase,UvrD_C k141_29658_4 1453501.JELR01000001_gene2198 0.0 939.0 COG1330@1|root,COG2887@1|root,COG1330@2|Bacteria,COG2887@2|Bacteria,1QVX1@1224|Proteobacteria,1RP9I@1236|Gammaproteobacteria,465DQ@72275|Alteromonadaceae 1236|Gammaproteobacteria L PD-(D/E)XK nuclease superfamily lidB - - - - - - - - - - - PDDEXK_1 k141_34369_1 666686.B1NLA3E_20390 1.66e-100 304.0 COG1027@1|root,COG1027@2|Bacteria,1TP3U@1239|Firmicutes,4HFM9@91061|Bacilli,1ZB5F@1386|Bacillus 91061|Bacilli E Aspartate ammonia-lyase aspA - 4.3.1.1 ko:K01744 ko00250,ko01100,map00250,map01100 - R00490 RC00316,RC02799 ko00000,ko00001,ko01000 - - - FumaraseC_C,Lyase_1 k141_36494_1 1453501.JELR01000001_gene3128 1.33e-64 211.0 COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,1RMBG@1236|Gammaproteobacteria,464KY@72275|Alteromonadaceae 1236|Gammaproteobacteria H Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control pcnB GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004652,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006276,GO:0006378,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0031123,GO:0031124,GO:0034641,GO:0043170,GO:0043412,GO:0043631,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070566,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 2.7.7.19 ko:K00970 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - PolyA_pol,PolyA_pol_RNAbd,PolyA_pol_arg_C k141_36494_2 317025.Tcr_1527 3.84e-45 152.0 COG0801@1|root,COG0801@2|Bacteria,1MZH8@1224|Proteobacteria,1S63J@1236|Gammaproteobacteria,460YW@72273|Thiotrichales 72273|Thiotrichales H PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK - - 2.7.6.3 ko:K00950 ko00790,ko01100,map00790,map01100 M00126,M00841 R03503 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - HPPK k141_36494_3 1453501.JELR01000001_gene3130 1.22e-34 124.0 COG1428@1|root,COG1428@2|Bacteria,1RC50@1224|Proteobacteria,1RRXT@1236|Gammaproteobacteria,464II@72275|Alteromonadaceae 1236|Gammaproteobacteria F Deoxynucleoside kinase dgk - - - - - - - - - - - dNK k141_33114_1 1235661.K0IK58_9CAUD 1.71e-57 189.0 4QNC3@10744|Podoviridae 10744|Podoviridae S endonuclease activity - - - - - - - - - - - - - k141_30515_1 1219065.VPR01S_09_01580 1.72e-26 103.0 COG4969@1|root,COG4969@2|Bacteria,1N7EQ@1224|Proteobacteria,1SCES@1236|Gammaproteobacteria,1XYET@135623|Vibrionales 135623|Vibrionales NU Belongs to the N-Me-Phe pilin family pilA - - ko:K02650 ko02020,map02020 - - - ko00000,ko00001,ko02035,ko02044 3.A.15.2 - - N_methyl,Pilin k141_30515_2 1219076.N646_1615 2.53e-111 325.0 COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,1RMBU@1236|Gammaproteobacteria,1XTQ3@135623|Vibrionales 135623|Vibrionales H Belongs to the NadC ModD family nadC - 2.4.2.19 ko:K00767 ko00760,ko01100,map00760,map01100 M00115 R03348 RC02877 ko00000,ko00001,ko00002,ko01000 - - - QRPTase_C,QRPTase_N k141_17683_1 714961.BFZC1_11082 3.53e-42 140.0 2E1PJ@1|root,32X01@2|Bacteria,1VCUD@1239|Firmicutes,4HMF9@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - k141_36495_1 218284.CCDN010000006_gene3663 7.86e-106 309.0 COG0569@1|root,COG0569@2|Bacteria,1TQ9H@1239|Firmicutes,4HBPH@91061|Bacilli,1ZQ63@1386|Bacillus 91061|Bacilli P TrkA-N domain ktrA GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K03499 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkA_C,TrkA_N k141_8024_1 218284.CCDN010000001_gene734 1.86e-211 597.0 COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,4HA9S@91061|Bacilli,1ZAZ2@1386|Bacillus 91061|Bacilli O Heat shock 70 kDa protein dnaK GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0030246,GO:0030247,GO:0044464,GO:0051704,GO:0098630,GO:0098743,GO:2001065 - ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 - - HSP70 k141_34371_1 218284.CCDN010000002_gene2838 3.61e-160 459.0 COG0277@1|root,COG0277@2|Bacteria,1TPBC@1239|Firmicutes,4H9UU@91061|Bacilli,1ZCQN@1386|Bacillus 91061|Bacilli C Glycolate oxidase subunit glcD - 1.1.3.15 ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001,ko01000 - - iYO844.BSU28680 FAD-oxidase_C,FAD_binding_4 k141_36496_1 1117108.PAALTS15_18363 1.94e-69 218.0 COG2141@1|root,COG2141@2|Bacteria,1TT4S@1239|Firmicutes,4HBJB@91061|Bacilli,26SP5@186822|Paenibacillaceae 91061|Bacilli C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases luxA_2 - - - - - - - - - - - Bac_luciferase k141_2168_1 218284.CCDN010000012_gene4442 9.39e-160 457.0 COG1388@1|root,COG3858@1|root,COG1388@2|Bacteria,COG3858@2|Bacteria,1TQK2@1239|Firmicutes,4HBJC@91061|Bacilli,1ZBQC@1386|Bacillus 91061|Bacilli M Glycoside Hydrolase Family yaaH - - ko:K06306 - - - - ko00000 - - - Glyco_hydro_18,LysM k141_29659_1 1042377.AFPJ01000036_gene1130 2e-165 468.0 COG3023@1|root,COG3023@2|Bacteria,1RDHU@1224|Proteobacteria,1RMDN@1236|Gammaproteobacteria,46BUP@72275|Alteromonadaceae 1236|Gammaproteobacteria V N-acetylmuramoyl-L-alanine amidase amiD_2 - 3.4.16.4,3.5.1.28 ko:K01447,ko:K21469 ko00550,map00550 - R04112 RC00064,RC00141 ko00000,ko00001,ko01000,ko01002,ko01011 - - - Amidase_2,Beta-lactamase,PG_binding_1,SH3_3 k141_29659_2 717774.Marme_3750 1.41e-45 149.0 COG2329@1|root,COG2329@2|Bacteria,1N062@1224|Proteobacteria,1SABZ@1236|Gammaproteobacteria,1XRIU@135619|Oceanospirillales 135619|Oceanospirillales S enzyme involved in biosynthesis of extracellular polysaccharides - - - - - - - - - - - - ABM k141_29659_3 1348663.KCH_08270 1.96e-64 212.0 COG1794@1|root,COG1794@2|Bacteria,2H7J9@201174|Actinobacteria,2M1AQ@2063|Kitasatospora 201174|Actinobacteria M Asp/Glu/Hydantoin racemase - - 5.1.1.13 ko:K01779 ko00250,ko01054,map00250,map01054 - R00491 RC00302 ko00000,ko00001,ko01000 - - - Asp_Glu_race k141_17685_1 42565.FP66_08345 2.38e-110 323.0 COG1291@1|root,COG1291@2|Bacteria,1MXK3@1224|Proteobacteria,1RNTF@1236|Gammaproteobacteria,1XI73@135619|Oceanospirillales 135619|Oceanospirillales N With MotB forms the ion channels that couple flagellar rotation to proton sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine motA - - ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - MotA_ExbB k141_16519_1 1453501.JELR01000002_gene624 3.6e-197 560.0 COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,1RNBR@1236|Gammaproteobacteria,464WA@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG1519 3-deoxy-D-manno-octulosonic-acid transferase waaA GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 ko:K02527 ko00540,ko01100,map00540,map01100 M00060,M00080 R04658,R05074,R09763 RC00009,RC00077,RC00247 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT30 iECNA114_1301.ECNA114_3778,iUMNK88_1353.UMNK88_4417 Glycos_transf_1,Glycos_transf_N k141_16519_2 1453501.JELR01000002_gene631 1.35e-82 257.0 COG1216@1|root,COG1216@2|Bacteria,1R59U@1224|Proteobacteria,1T2A6@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Glycosyl transferase, family 2 - - - - - - - - - - - - Glycos_transf_2 k141_15218_1 218284.CCDN010000001_gene1775 3.94e-62 221.0 COG0419@1|root,COG0419@2|Bacteria,1TPCS@1239|Firmicutes,4H9Q3@91061|Bacilli,1ZAP5@1386|Bacillus 91061|Bacilli L COG0419 ATPase involved in DNA repair sbcC - - ko:K03546 - - - - ko00000,ko03400 - - - AAA_23,AAA_29,SbcCD_C k141_8025_1 1122194.AUHU01000001_gene67 1.14e-77 252.0 COG2017@1|root,COG3940@1|root,COG2017@2|Bacteria,COG3940@2|Bacteria,1MVMN@1224|Proteobacteria,1RNZN@1236|Gammaproteobacteria,464QA@72275|Alteromonadaceae 1236|Gammaproteobacteria G Converts alpha-aldose to the beta-anomer galM - 5.1.3.3 ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 M00632 R01602,R10619 RC00563 ko00000,ko00001,ko00002,ko01000 - - - Aldose_epim k141_34372_1 1453501.JELR01000001_gene3047 1.02e-86 268.0 COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,1RP25@1236|Gammaproteobacteria,465HJ@72275|Alteromonadaceae 1236|Gammaproteobacteria M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) murD GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008764,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - iAPECO1_1312.APECO1_1898,iECNA114_1301.ECNA114_0081,iECOK1_1307.ECOK1_0089,iECP_1309.ECP_0090,iECS88_1305.ECS88_0091,iECSF_1327.ECSF_0098,iLF82_1304.LF82_1418,iNRG857_1313.NRG857_00450,iUMN146_1321.UM146_23225,iUTI89_1310.UTI89_C0097 Mur_ligase_C,Mur_ligase_M k141_3389_1 1453501.JELR01000002_gene1491 2.99e-153 435.0 COG0730@1|root,COG0730@2|Bacteria,1R3V4@1224|Proteobacteria,1RVNC@1236|Gammaproteobacteria,466K2@72275|Alteromonadaceae 1236|Gammaproteobacteria S membrane transporter protein - - - - - - - - - - - - TauE k141_3389_2 1453501.JELR01000002_gene1490 5.75e-193 543.0 COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,1RZAD@1236|Gammaproteobacteria,46890@72275|Alteromonadaceae 1236|Gammaproteobacteria E Aminotransferase class I and II hisC2 - 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k141_3389_3 551275.KB899545_gene2991 7.36e-40 149.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MUNK@1224|Proteobacteria,2TRCG@28211|Alphaproteobacteria,43WM8@69657|Hyphomonadaceae 28211|Alphaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_2169_1 218284.CCDN010000001_gene1225 1.27e-82 251.0 COG0515@1|root,COG0515@2|Bacteria,1UZEH@1239|Firmicutes,4IPW7@91061|Bacilli,1ZRE1@1386|Bacillus 91061|Bacilli KLT Protein tyrosine kinase - - 2.7.11.1 ko:K08884 - - - - ko00000,ko01000,ko01001 - - - Pkinase k141_30516_1 218284.CCDN010000007_gene3978 3.5e-76 229.0 2F411@1|root,33WSR@2|Bacteria,1VVIK@1239|Firmicutes,4HW8P@91061|Bacilli,1ZGVA@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_36497_1 768066.HELO_1296 1.05e-107 327.0 COG0028@1|root,COG0028@2|Bacteria,1MWVW@1224|Proteobacteria,1RPZ2@1236|Gammaproteobacteria 1236|Gammaproteobacteria EH Belongs to the TPP enzyme family - - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N k141_8070_1 1279017.AQYJ01000028_gene2040 2.77e-25 103.0 2DBVC@1|root,2ZBAF@2|Bacteria,1PT3T@1224|Proteobacteria,1RZJK@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Psort location CytoplasmicMembrane, score 9.46 - - - - - - - - - - - - - k141_8070_2 1380600.AUYN01000009_gene1522 1.16e-61 200.0 COG2755@1|root,COG2755@2|Bacteria 2|Bacteria E lipolytic protein G-D-S-L family - - 3.1.1.5 ko:K10804 ko01040,map01040 - - - ko00000,ko00001,ko01000,ko01004 - - - SASA k141_28265_2 218284.CCDN010000002_gene2095 7.59e-204 564.0 COG3327@1|root,COG3327@2|Bacteria,1TRBU@1239|Firmicutes,4HCP9@91061|Bacilli,1ZD7Z@1386|Bacillus 91061|Bacilli K PaaX-like protein paaX - - ko:K02616 - - - - ko00000,ko03000 - - - PaaX,PaaX_C k141_21220_2 218284.CCDN010000001_gene1030 1.7e-26 99.4 2EGUT@1|root,33AKY@2|Bacteria,1VKYE@1239|Firmicutes,4HRB5@91061|Bacilli,1ZJ1Z@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3886) - - - - - - - - - - - - DUF3886 k141_36545_1 218284.CCDN010000007_gene3936 2.67e-145 416.0 COG0280@1|root,COG0280@2|Bacteria,1TPQ0@1239|Firmicutes,4H9VH@91061|Bacilli,1ZC98@1386|Bacillus 91061|Bacilli C In Salmonella this enzyme is required for ethanolamine catabolism pta - 2.3.1.8,3.6.3.21 ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00236,M00357,M00579 R00230,R00921 RC00004,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3 - iSB619.SA_RS03155 PTA_PTB k141_36545_2 218284.CCDN010000007_gene3935 2.19e-174 486.0 COG3253@1|root,COG3253@2|Bacteria,1TQB2@1239|Firmicutes,4H9YI@91061|Bacilli,1ZAZY@1386|Bacillus 91061|Bacilli C May function as heme-dependent peroxidase ywfI - - ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 - R11522 RC00884 ko00000,ko00001,ko01000 - - - Chlor_dismutase k141_33154_1 1279017.AQYJ01000022_gene2689 9.18e-103 327.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,46425@72275|Alteromonadaceae 1236|Gammaproteobacteria V Efflux pump mexF - - ko:K18138,ko:K18299,ko:K19585 ko01501,ko01503,map01501,map01503 M00641,M00647,M00699,M00718,M00767 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2,2.A.6.2.16,2.A.6.2.47 - - ACR_tran k141_33154_2 1318628.MARLIPOL_09521 1.09e-43 157.0 COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,1RN5K@1236|Gammaproteobacteria,466GP@72275|Alteromonadaceae 1236|Gammaproteobacteria MU Outer membrane efflux protein - - - ko:K18300 - M00641 - - ko00000,ko00002,ko01504,ko02000 1.B.17 - - OEP k141_30546_2 938709.AUSH02000001_gene1617 3.91e-24 99.8 COG0596@1|root,COG0596@2|Bacteria,4NEY1@976|Bacteroidetes 976|Bacteroidetes S Serine aminopeptidase, S33 - - - - - - - - - - - - Abhydrolase_1 k141_10654_1 42565.FP66_03530 2.43e-103 301.0 COG0218@1|root,COG0218@2|Bacteria,1MY3Z@1224|Proteobacteria,1RNJP@1236|Gammaproteobacteria,1XJCE@135619|Oceanospirillales 135619|Oceanospirillales D Necessary for normal cell division and for the maintenance of normal septation engB - - ko:K03978 - - - - ko00000,ko03036 - - - MMR_HSR1 k141_3434_1 1453501.JELR01000006_gene13 1.9e-98 313.0 COG4223@1|root,COG4223@2|Bacteria,1N10X@1224|Proteobacteria,1RYCQ@1236|Gammaproteobacteria,46D2D@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF1631) - - - - - - - - - - - - DUF1631 k141_36546_1 218284.CCDN010000005_gene3404 2.39e-67 218.0 COG1757@1|root,COG1757@2|Bacteria,1TP8A@1239|Firmicutes,4HB2I@91061|Bacilli,1ZCTW@1386|Bacillus 91061|Bacilli C Na+/H+ antiporter family nhaC2 - - - - - - - - - - - Na_H_antiporter k141_31699_1 1453501.JELR01000002_gene1258 1.53e-316 892.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RS1Q@1236|Gammaproteobacteria,469PS@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_8071_1 218284.CCDN010000008_gene4250 1.76e-37 131.0 29TEB@1|root,30EMG@2|Bacteria,1UCQK@1239|Firmicutes,4IP6T@91061|Bacilli,1ZPGM@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_8071_2 218284.CCDN010000008_gene4251 1.04e-78 251.0 COG2199@1|root,COG2203@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,1TQ2X@1239|Firmicutes,4HA6T@91061|Bacilli,1ZCE7@1386|Bacillus 91061|Bacilli T COG2199 FOG GGDEF domain ytrP - - - - - - - - - - - GAF_2,GAF_3,GGDEF k141_2220_1 518766.Rmar_2700 2.03e-81 262.0 COG0773@1|root,COG0773@2|Bacteria,4NE1V@976|Bacteroidetes,1FJ2E@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes M Mur ligase family, catalytic domain murC - 6.3.2.8 ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M k141_28266_1 1026882.MAMP_00234 2.46e-45 151.0 28PDJ@1|root,2ZC5G@2|Bacteria,1RCPJ@1224|Proteobacteria,1S3C7@1236|Gammaproteobacteria,462S2@72273|Thiotrichales 72273|Thiotrichales - - - - - - - - - - - - - - - k141_28266_2 1123279.ATUS01000004_gene2991 4.63e-33 116.0 2CCNX@1|root,32RW4@2|Bacteria,1N3P1@1224|Proteobacteria,1SAFG@1236|Gammaproteobacteria,1J7BH@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_28266_3 983545.Glaag_4449 3.17e-37 132.0 COG4319@1|root,COG4319@2|Bacteria,1N6PB@1224|Proteobacteria,1RQHB@1236|Gammaproteobacteria,4681Y@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF4440) - - - - - - - - - - - - DUF4440,SnoaL_3 k141_31700_1 218284.CCDN010000005_gene3374 8.2e-119 350.0 COG1850@1|root,COG1850@2|Bacteria,1TSZQ@1239|Firmicutes,4HBIK@91061|Bacilli,1ZC2J@1386|Bacillus 91061|Bacilli G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P) mtnW GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0009853,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0016984,GO:0043094,GO:0044237 5.3.2.5 ko:K08965 ko00270,ko01100,map00270,map01100 M00034 R07393 RC02421 ko00000,ko00001,ko00002,ko01000 - - - RuBisCO_large,RuBisCO_large_N k141_16566_2 218284.CCDN010000001_gene1914 6.38e-78 236.0 COG1684@1|root,COG1684@2|Bacteria,1TRB2@1239|Firmicutes,4HA2E@91061|Bacilli,1ZBJF@1386|Bacillus 91061|Bacilli N Flagellar biosynthetic protein FliR fliR - - ko:K02421 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - Bac_export_1 k141_10656_1 218284.CCDN010000005_gene3164 4.69e-172 483.0 COG4152@1|root,COG4152@2|Bacteria,1TR06@1239|Firmicutes,4H9RX@91061|Bacilli,1ZC9T@1386|Bacillus 91061|Bacilli S ABC transporter, ATP-binding protein yhaQ - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 k141_8072_1 1279017.AQYJ01000022_gene2679 2.1e-34 130.0 COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,1RP5S@1236|Gammaproteobacteria,465XU@72275|Alteromonadaceae 1236|Gammaproteobacteria S Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state bepA GO:0003674,GO:0003756,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005575,GO:0005623,GO:0006457,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016043,GO:0016787,GO:0016853,GO:0016860,GO:0016864,GO:0019538,GO:0022607,GO:0030163,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043163,GO:0043165,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044091,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044464,GO:0045229,GO:0046872,GO:0051603,GO:0061024,GO:0061077,GO:0070011,GO:0071704,GO:0071709,GO:0071840,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - - - - - - - - - - Peptidase_M48,TPR_19 k141_33157_1 218284.CCDN010000001_gene1741 5.93e-124 359.0 COG0584@1|root,COG0584@2|Bacteria,1UY23@1239|Firmicutes,4HEAD@91061|Bacilli,1ZCIE@1386|Bacillus 91061|Bacilli C glycerophosphoryl diester phosphodiesterase glpQ - 3.1.3.1,3.1.4.46 ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 M00126 R01030,R01470,R04620 RC00017,RC00425 ko00000,ko00001,ko00002,ko01000 - - - GDPD,PhoD,PhoD_N k141_30547_1 218284.CCDN010000002_gene2219 8.4e-45 155.0 COG1017@1|root,COG1018@1|root,COG1017@2|Bacteria,COG1018@2|Bacteria,1TRG2@1239|Firmicutes,4HAU3@91061|Bacilli,1ZAP9@1386|Bacillus 91061|Bacilli C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress hmp GO:0000166,GO:0001505,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008941,GO:0009056,GO:0009987,GO:0016491,GO:0016705,GO:0016708,GO:0017144,GO:0033554,GO:0034641,GO:0036094,GO:0042133,GO:0042135,GO:0042737,GO:0043167,GO:0043168,GO:0044237,GO:0044248,GO:0044270,GO:0044464,GO:0046209,GO:0046210,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051213,GO:0051409,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0071500,GO:0071949,GO:0072593,GO:0097159,GO:1901265,GO:1901363,GO:2001057 1.14.12.17,1.18.1.3 ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 M00538 R02550,R03562,R05666,R09513 RC00269,RC00490,RC02556 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_6,Globin,NAD_binding_1 k141_30547_2 218284.CCDN010000002_gene2220 9.74e-29 103.0 29RXQ@1|root,30D20@2|Bacteria,1UAQ9@1239|Firmicutes,4IM2Y@91061|Bacilli,1ZIYI@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_30547_3 997296.PB1_04325 1.34e-45 151.0 2D7FD@1|root,32TNY@2|Bacteria,1VADP@1239|Firmicutes,4HKCW@91061|Bacilli,1ZI9Y@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF1992) ydhN1 - - - - - - - - - - - DUF1992 k141_3437_1 1041142.ATTP01000004_gene4439 1.81e-12 65.9 COG1129@1|root,COG1129@2|Bacteria,1MVNR@1224|Proteobacteria,2TTCM@28211|Alphaproteobacteria,4BA19@82115|Rhizobiaceae 28211|Alphaproteobacteria G ABC transporter - - 3.6.3.17 ko:K02056 - M00221 - - ko00000,ko00002,ko01000,ko02000 3.A.1.2 - - ABC_tran k141_3437_2 311402.Avi_7476 4.55e-67 214.0 COG1172@1|root,COG1172@2|Bacteria,1MX7D@1224|Proteobacteria,2TVQM@28211|Alphaproteobacteria,4B915@82115|Rhizobiaceae 28211|Alphaproteobacteria G Ribose xylose arabinose galactoside ABC-type transport systems, permease components - - - ko:K02057 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - BPD_transp_2 k141_31701_2 316067.Geob_3558 4.4e-10 63.2 COG0705@1|root,COG0705@2|Bacteria,1PRTP@1224|Proteobacteria,42M6N@68525|delta/epsilon subdivisions,2WJW4@28221|Deltaproteobacteria,43U9M@69541|Desulfuromonadales 28221|Deltaproteobacteria S Rhomboid family - - 3.4.21.105 ko:K19225 - - - - ko00000,ko01000,ko01002 - - - Rhomboid k141_17726_1 1307436.PBF_24825 6.27e-41 137.0 COG2963@1|root,COG2963@2|Bacteria,1VP6M@1239|Firmicutes,4HRHX@91061|Bacilli,1ZIZ1@1386|Bacillus 91061|Bacilli L COG2963 Transposase and inactivated derivatives - - - ko:K07483 - - - - ko00000 - - - HTH_Tnp_1 k141_17726_2 1307436.PBF_24820 3.92e-50 167.0 COG2801@1|root,COG2801@2|Bacteria,1TU21@1239|Firmicutes,4HDK4@91061|Bacilli,1ZB1J@1386|Bacillus 91061|Bacilli L COG2801 Transposase and inactivated derivatives - - - ko:K07497 - - - - ko00000 - - - HTH_21,rve k141_2222_1 882.DVU_1298 4.66e-68 208.0 COG0048@1|root,COG0048@2|Bacteria,1RCWY@1224|Proteobacteria,42RDQ@68525|delta/epsilon subdivisions,2WND8@28221|Deltaproteobacteria,2MBJ6@213115|Desulfovibrionales 28221|Deltaproteobacteria J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit rpsL - - ko:K02950 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosom_S12_S23 k141_2222_2 1288298.rosmuc_02334 9.78e-14 67.8 COG0049@1|root,COG0049@2|Bacteria,1MXC8@1224|Proteobacteria,2TSI8@28211|Alphaproteobacteria,46NHK@74030|Roseovarius 28211|Alphaproteobacteria J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA rpsG GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02992 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S7 k141_10657_1 997296.PB1_16594 1.05e-106 323.0 28KBQ@1|root,2Z9YP@2|Bacteria,1TT8R@1239|Firmicutes,4IRFF@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - k141_2223_1 1504981.KO116_1998 1.16e-08 55.8 COG1105@1|root,COG1105@2|Bacteria,1MVNW@1224|Proteobacteria,1RP6K@1236|Gammaproteobacteria,1XPSB@135619|Oceanospirillales 135619|Oceanospirillales G belongs to the carbohydrate kinase PfkB family - - 2.7.1.56 ko:K00882 ko00051,map00051 - R02071 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB k141_2223_2 1121939.L861_10875 2.27e-51 178.0 COG1299@1|root,COG1445@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,1MXFN@1224|Proteobacteria,1RMZC@1236|Gammaproteobacteria,1XNAY@135619|Oceanospirillales 135619|Oceanospirillales G PTS fructose transporter subunit fruA - 2.7.1.202 ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1 - - PTS_EIIC,PTS_IIB k141_21223_1 1462526.BN990_01821 8.61e-27 104.0 COG3935@1|root,COG3935@2|Bacteria,1V9YA@1239|Firmicutes,4HN3B@91061|Bacilli 91061|Bacilli L primosome component and related proteins - - - - - - - - - - - - DnaB_2 k141_30548_1 218284.CCDN010000001_gene1265 1.21e-61 194.0 COG0307@1|root,COG0307@2|Bacteria,1V1EP@1239|Firmicutes,4HC7B@91061|Bacilli,1ZBB9@1386|Bacillus 91061|Bacilli H Riboflavin synthase ribE GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9 ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00066 RC00958,RC00960 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS08950,iYO844.BSU23270 Lum_binding k141_30548_2 218284.CCDN010000001_gene1266 1.49e-120 353.0 COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1TPH9@1239|Firmicutes,4H9PW@91061|Bacilli,1ZBF9@1386|Bacillus 91061|Bacilli H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate ribBA GO:0003674,GO:0003824,GO:0003933,GO:0003935,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0019238,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.5.4.25,4.1.99.12 ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 M00125,M00840 R00425,R07281 RC00293,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS08945 DHBP_synthase,GTP_cyclohydro2 k141_2587_1 1116375.VEJY3_16186 4.9e-116 337.0 COG2145@1|root,COG2145@2|Bacteria,1MVES@1224|Proteobacteria,1RRAE@1236|Gammaproteobacteria,1XSM9@135623|Vibrionales 135623|Vibrionales H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ) thiM - 2.7.1.50 ko:K00878 ko00730,ko01100,map00730,map01100 M00127 R04448 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - HK k141_2587_2 1280001.BAOA01000014_gene960 2.2e-23 94.4 COG0819@1|root,COG0819@2|Bacteria,1R21S@1224|Proteobacteria,1RQY6@1236|Gammaproteobacteria,1XUAI@135623|Vibrionales 135623|Vibrionales K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway - - 3.5.99.2 ko:K03707 ko00730,ko01100,map00730,map01100 - R02133,R09993 RC00224,RC00652,RC02832 ko00000,ko00001,ko01000,ko03000 - - - TENA_THI-4 k141_6211_1 1307436.PBF_21618 9.85e-32 120.0 COG0327@1|root,COG0327@2|Bacteria,1TQ27@1239|Firmicutes,4H9NY@91061|Bacilli,1ZAPV@1386|Bacillus 91061|Bacilli S Belongs to the GTP cyclohydrolase I type 2 NIF3 family yqfO GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - - - - - - - - - - NIF3 k141_6211_2 1294265.JCM21738_2856 1.06e-145 413.0 COG2384@1|root,COG2384@2|Bacteria,1V3I4@1239|Firmicutes,4HHIM@91061|Bacilli,1ZE5B@1386|Bacillus 91061|Bacilli S SAM-dependent methyltransferase trmK GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.217 ko:K06967 - - - - ko00000,ko01000,ko03016 - - - TrmK k141_22764_2 270374.MELB17_06124 1.14e-35 130.0 COG2130@1|root,COG2130@2|Bacteria,1MUC2@1224|Proteobacteria,1RNGM@1236|Gammaproteobacteria,465JP@72275|Alteromonadaceae 1236|Gammaproteobacteria S NADP-dependent - - - ko:K07119 - - - - ko00000 - - - ADH_N_2,ADH_zinc_N k141_4917_2 1453501.JELR01000001_gene2586 9.79e-64 202.0 2ECZP@1|root,336WQ@2|Bacteria,1NBQI@1224|Proteobacteria,1SEN0@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - ko:K03646 - - - - ko00000,ko02000 2.C.1.2 - - GIY-YIG k141_4917_3 1042377.AFPJ01000016_gene121 0.0 1092.0 COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,1RNA5@1236|Gammaproteobacteria,4641A@72275|Alteromonadaceae 1236|Gammaproteobacteria P Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity katG GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.11.1.21 ko:K03782 ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110 - R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906 RC00034,RC00213,RC00767,RC02141 ko00000,ko00001,ko01000 - - - peroxidase k141_34659_1 1294265.JCM21738_3643 7.99e-40 139.0 COG1694@1|root,COG3956@2|Bacteria,1TPK1@1239|Firmicutes,4HA0A@91061|Bacilli,1ZAYB@1386|Bacillus 91061|Bacilli S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like yabN GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.66 ko:K02428,ko:K02499 ko00230,map00230 - R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000,ko03036 - - - MazG,TP_methylase k141_34659_2 1294265.JCM21738_3644 3.66e-53 167.0 COG1188@1|root,COG1188@2|Bacteria,1VEI5@1239|Firmicutes,4HKJJ@91061|Bacilli,1ZHXN@1386|Bacillus 91061|Bacilli J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) yabO - - - - - - - - - - - S4 k141_34659_3 1294265.JCM21738_3645 5.2e-17 73.9 2E3ZZ@1|root,32YWW@2|Bacteria,1VEIW@1239|Firmicutes,4HPDE@91061|Bacilli,1ZGYU@1386|Bacillus 91061|Bacilli S Sporulation protein YabP yabP GO:0005575,GO:0005623,GO:0042601,GO:0042763,GO:0044464 - - - - - - - - - - YabP k141_9668_1 218284.CCDN010000007_gene3966 3.46e-165 467.0 COG1172@1|root,COG1172@2|Bacteria,1TP72@1239|Firmicutes,4HBU9@91061|Bacilli,1ZQAD@1386|Bacillus 91061|Bacilli G Belongs to the binding-protein-dependent transport system permease family rbsC3 - - ko:K02057 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - BPD_transp_2 k141_265_2 1042377.AFPJ01000032_gene2738 4.4e-05 45.4 COG0500@1|root,COG0640@1|root,COG0640@2|Bacteria,COG2226@2|Bacteria,1NFSV@1224|Proteobacteria,1RQT6@1236|Gammaproteobacteria,464PH@72275|Alteromonadaceae 1236|Gammaproteobacteria K Transcriptional regulators - - - - - - - - - - - - HTH_20,HTH_5,Methyltransf_11,Methyltransf_23,Methyltransf_31 k141_33442_1 1116375.VEJY3_16076 1.08e-94 276.0 COG1522@1|root,COG1522@2|Bacteria,1MX7R@1224|Proteobacteria,1S61U@1236|Gammaproteobacteria,1XX50@135623|Vibrionales 135623|Vibrionales K COG1522 Transcriptional regulators - - - - - - - - - - - - AsnC_trans_reg,HTH_24 k141_33442_2 674977.VMC_04790 1.27e-254 701.0 COG3397@1|root,COG3979@1|root,COG3397@2|Bacteria,COG3979@2|Bacteria,1NX7A@1224|Proteobacteria,1RRDI@1236|Gammaproteobacteria,1XV85@135623|Vibrionales 135623|Vibrionales S Lytic polysaccharide mono-oxygenase, cellulose-degrading - - - ko:K03933 - - - - ko00000 - AA10,CBM73 - CBM_5_12,LPMO_10 k141_33442_3 1280001.BAOA01000040_gene2454 2.04e-56 176.0 COG1917@1|root,COG1917@2|Bacteria,1MZNT@1224|Proteobacteria,1S8TU@1236|Gammaproteobacteria,1XYMY@135623|Vibrionales 135623|Vibrionales S Cupin domain - - - ko:K11312 - - - - ko00000 - - - Cupin_2 k141_33442_4 223926.28808234 7.11e-121 347.0 COG3047@1|root,COG3047@2|Bacteria,1NUZJ@1224|Proteobacteria,1RRRC@1236|Gammaproteobacteria,1XSCD@135623|Vibrionales 135623|Vibrionales M Outer membrane protein W ompW GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - ko:K07275 - - - - ko00000 - - - OmpW k141_1331_1 1116375.VEJY3_14830 2.35e-260 717.0 COG1502@1|root,COG1502@2|Bacteria,1MVPU@1224|Proteobacteria,1RN1V@1236|Gammaproteobacteria,1XT62@135623|Vibrionales 135623|Vibrionales I COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes pssA - 2.7.8.8 ko:K00998 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 M00093 R01800 RC00002,RC00017,RC02795 ko00000,ko00001,ko00002,ko01000 - - - PLDc_2,Regulator_TrmB k141_1331_2 223926.28807959 2.91e-75 228.0 COG3153@1|root,COG3153@2|Bacteria,1QUGJ@1224|Proteobacteria,1T1YA@1236|Gammaproteobacteria,1XYFN@135623|Vibrionales 135623|Vibrionales S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - - - - - - - - - - Acetyltransf_10,Acetyltransf_7 k141_1331_3 1219076.N646_2006 8.13e-210 584.0 COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,1RNXK@1236|Gammaproteobacteria,1XTDX@135623|Vibrionales 135623|Vibrionales M Cell wall formation murB GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008762,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0055114,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 1.3.1.98 ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R03191,R03192 RC02639 ko00000,ko00001,ko01000,ko01011 - - - FAD_binding_4,MurB_C k141_1331_4 1116375.VEJY3_14815 3.52e-207 575.0 COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1MWCC@1224|Proteobacteria,1RNGC@1236|Gammaproteobacteria,1XUFE@135623|Vibrionales 135623|Vibrionales H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon birA - 6.3.4.15 ko:K03524 ko00780,ko01100,map00780,map01100 - R01074,R05145 RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko01000,ko03000 - - - BPL_C,BPL_LplA_LipB,HTH_11 k141_1331_5 1116375.VEJY3_14810 4.24e-217 599.0 COG1072@1|root,COG1072@2|Bacteria,1MV3M@1224|Proteobacteria,1RNXX@1236|Gammaproteobacteria,1XUCB@135623|Vibrionales 135623|Vibrionales F pantothenic acid kinase coaA GO:0003674,GO:0003824,GO:0004594,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.33 ko:K00867 ko00770,ko01100,map00770,map01100 M00120 R02971,R03018,R04391 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - PRK k141_2588_2 1007103.AFHW01000181_gene764 5.93e-19 88.2 COG0438@1|root,COG0438@2|Bacteria,1V2PF@1239|Firmicutes,4HH5A@91061|Bacilli,26RPT@186822|Paenibacillaceae 91061|Bacilli M Glycosyl transferases group 1 ytcC - - ko:K06338 - - - - ko00000 - - - Glyco_transf_4,Glycos_transf_1 k141_20339_1 330396.A8AT95_9CAUD 3.61e-142 417.0 4QBV3@10239|Viruses,4QW0W@35237|dsDNA viruses no RNA stage,4QPPJ@28883|Caudovirales,4QKW5@10699|Siphoviridae 10699|Siphoviridae S Phage Terminase - - - - - - - - - - - - - k141_26386_1 593907.Celgi_3182 4.19e-26 101.0 COG0359@1|root,COG0359@2|Bacteria,2IKX7@201174|Actinobacteria,4F19C@85016|Cellulomonadaceae 201174|Actinobacteria J Binds to the 23S rRNA rplI GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02939 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L9_C,Ribosomal_L9_N k141_26386_2 639282.DEFDS_1989 4.01e-13 65.1 COG0238@1|root,COG0238@2|Bacteria,2GFVY@200930|Deferribacteres 200930|Deferribacteres J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit rpsR - - ko:K02963 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S18 k141_13290_1 218284.CCDN010000006_gene3624 2.61e-97 296.0 COG1215@1|root,COG1215@2|Bacteria,1TR2P@1239|Firmicutes,4HAQN@91061|Bacilli,1ZCR1@1386|Bacillus 91061|Bacilli M Glycosyl transferase family group 2 icaA - - - - - - - - - - - Chitin_synth_2,Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_2 k141_13290_2 545693.BMQ_0936 1.15e-05 47.4 COG1413@1|root,COG1413@2|Bacteria,1V32S@1239|Firmicutes,4HFCX@91061|Bacilli,1ZR98@1386|Bacillus 91061|Bacilli C COG1413 FOG HEAT repeat - - - - - - - - - - - - HEAT k141_9669_2 935837.JAEK01000006_gene4155 2.26e-92 275.0 COG1028@1|root,COG1028@2|Bacteria,1TSND@1239|Firmicutes,4HAU2@91061|Bacilli,1ZEY4@1386|Bacillus 91061|Bacilli IQ Enoyl-(Acyl carrier protein) reductase - - - - - - - - - - - - adh_short,adh_short_C2 k141_16814_1 315730.BcerKBAB4_1944 1.1e-09 58.9 COG0454@1|root,COG0456@2|Bacteria,1V1J9@1239|Firmicutes,4HMZA@91061|Bacilli,1ZQPS@1386|Bacillus 91061|Bacilli K FR47-like protein - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10 k141_16814_2 1294265.JCM21738_526 3.5e-30 111.0 COG2039@1|root,COG2039@2|Bacteria,1TRRX@1239|Firmicutes,4HCIJ@91061|Bacilli,1ZEI9@1386|Bacillus 91061|Bacilli O Removes 5-oxoproline from various penultimate amino acid residues except L-proline pcp GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0071704,GO:1901564 3.4.19.3 ko:K01304 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C15 k141_292_4 1042377.AFPJ01000020_gene2077 6e-123 357.0 COG1189@1|root,COG1189@2|Bacteria,1MWP5@1224|Proteobacteria,1S28A@1236|Gammaproteobacteria,466PV@72275|Alteromonadaceae 1236|Gammaproteobacteria J FtsJ-like methyltransferase - - 2.1.1.226,2.1.1.227 ko:K06442 - - - - ko00000,ko01000,ko03009 - - - FtsJ,S4 k141_3813_1 1116375.VEJY3_08150 9.04e-297 813.0 COG1115@1|root,COG1115@2|Bacteria,1MUI3@1224|Proteobacteria,1RMNF@1236|Gammaproteobacteria,1XUBZ@135623|Vibrionales 135623|Vibrionales U COG1115 Na alanine symporter - - - ko:K03310 - - - - ko00000 2.A.25 - - Na_Ala_symp k141_3813_2 1116375.VEJY3_08165 7.01e-222 613.0 COG2141@1|root,COG2141@2|Bacteria,1MVF0@1224|Proteobacteria,1RMCE@1236|Gammaproteobacteria,1XVRB@135623|Vibrionales 135623|Vibrionales C Luciferase-like monooxygenase - - - - - - - - - - - - Bac_luciferase k141_3813_3 1116375.VEJY3_08170 1.41e-134 383.0 COG1280@1|root,COG1280@2|Bacteria,1R7UJ@1224|Proteobacteria,1RYYM@1236|Gammaproteobacteria,1Y2Y3@135623|Vibrionales 135623|Vibrionales E threonine efflux protein - - - - - - - - - - - - LysE k141_3813_4 1116375.VEJY3_08175 0.0 921.0 COG2317@1|root,COG2317@2|Bacteria,1MW7T@1224|Proteobacteria,1RQM5@1236|Gammaproteobacteria,1XTZ9@135623|Vibrionales 135623|Vibrionales E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues - - 3.4.17.19 ko:K01299 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M32 k141_3813_5 1116375.VEJY3_08200 1.71e-87 265.0 COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,1RMZ5@1236|Gammaproteobacteria,1XSK3@135623|Vibrionales 135623|Vibrionales M Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)- (lauroyl)-lipid IV(A) lpxL - 2.3.1.241 ko:K02517 ko00540,ko01100,map00540,map01100 M00060 R05146 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Lip_A_acyltrans k141_1361_1 1178482.BJB45_01745 2.61e-279 770.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RQ36@1236|Gammaproteobacteria,1XH88@135619|Oceanospirillales 135619|Oceanospirillales L Belongs to the DEAD box helicase family dbpA - 3.6.4.13 ko:K05591 - - - - ko00000,ko01000,ko03009 - - - DEAD,DbpA,Helicase_C k141_1361_2 1449049.JONW01000010_gene3674 8.72e-97 302.0 COG4299@1|root,COG4299@2|Bacteria,1R5FB@1224|Proteobacteria,2UPA5@28211|Alphaproteobacteria,2KI44@204458|Caulobacterales 204458|Caulobacterales S COGs COG4299 conserved - - - - - - - - - - - - - k141_1361_4 1279017.AQYJ01000029_gene3672 9.2e-92 281.0 COG0510@1|root,COG0510@2|Bacteria,1MURU@1224|Proteobacteria,1SAW7@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Aminoglycoside phosphotransferase - - - - - - - - - - - - APH,Choline_kinase k141_1361_5 1042377.AFPJ01000034_gene2312 1.65e-31 116.0 COG3201@1|root,COG3201@2|Bacteria,1MXN4@1224|Proteobacteria,1RMZE@1236|Gammaproteobacteria,467GF@72275|Alteromonadaceae 1236|Gammaproteobacteria H nicotinamide mononucleotide transporter pnuC - - ko:K03811 - - - - ko00000,ko02000 4.B.1.1 - - NMN_transporter k141_29883_1 1056820.KB900685_gene2812 4.83e-87 287.0 COG3266@1|root,COG3266@2|Bacteria,1NMZ5@1224|Proteobacteria,1SX8D@1236|Gammaproteobacteria,2PP5X@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria S Domain of unknown function (DUF5011) - - - - - - - - - - - - DUF5011 k141_29883_2 754476.Q7A_1415 0.000937 45.1 COG3307@1|root,COG3307@2|Bacteria,1MV4S@1224|Proteobacteria,1S15Z@1236|Gammaproteobacteria,461NP@72273|Thiotrichales 72273|Thiotrichales M O-antigen ligase like membrane protein - - - - - - - - - - - - - k141_34660_2 644801.Psest_1326 6.45e-23 102.0 COG5607@1|root,COG5607@2|Bacteria,1RH6R@1224|Proteobacteria,1S7KA@1236|Gammaproteobacteria,1Z0XH@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria S CHAD - - - - - - - - - - - - CHAD k141_34660_3 1453501.JELR01000001_gene2984 3.05e-77 233.0 COG1585@1|root,COG1585@2|Bacteria,1N4FG@1224|Proteobacteria,1S4V9@1236|Gammaproteobacteria,46CZM@72275|Alteromonadaceae 1236|Gammaproteobacteria OU NfeD-like C-terminal, partner-binding - - - ko:K07340 - - - - ko00000 - - - NfeD k141_34660_4 1042377.AFPJ01000034_gene2421 1.54e-158 449.0 COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,1RNW8@1236|Gammaproteobacteria,465XW@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG0330 Membrane protease subunits, stomatin prohibitin homologs - - - - - - - - - - - - Band_7,Band_7_C k141_34660_5 1279017.AQYJ01000029_gene3672 4.06e-90 276.0 COG0510@1|root,COG0510@2|Bacteria,1MURU@1224|Proteobacteria,1SAW7@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Aminoglycoside phosphotransferase - - - - - - - - - - - - APH,Choline_kinase k141_34660_6 1279017.AQYJ01000029_gene3673 1.57e-103 305.0 COG3201@1|root,COG3201@2|Bacteria,1MXN4@1224|Proteobacteria,1RMZE@1236|Gammaproteobacteria,467GF@72275|Alteromonadaceae 1236|Gammaproteobacteria H nicotinamide mononucleotide transporter pnuC - - ko:K03811 - - - - ko00000,ko02000 4.B.1.1 - - NMN_transporter k141_34660_8 1453501.JELR01000001_gene3106 0.0 1009.0 COG4773@1|root,COG4773@2|Bacteria,1QTXJ@1224|Proteobacteria,1T2NX@1236|Gammaproteobacteria,46D3S@72275|Alteromonadaceae 1236|Gammaproteobacteria P TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_34660_9 1453501.JELR01000002_gene1257 1.12e-249 701.0 COG1785@1|root,COG1785@2|Bacteria,1MXI2@1224|Proteobacteria,1RNG8@1236|Gammaproteobacteria,4666G@72275|Alteromonadaceae 1236|Gammaproteobacteria P Belongs to the alkaline phosphatase family phoA - 3.1.3.1 ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 M00126 R02135,R04620 RC00017 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 - - - Alk_phosphatase k141_34660_10 1279017.AQYJ01000027_gene1932 4.49e-63 195.0 COG3536@1|root,COG3536@2|Bacteria,1MZ5M@1224|Proteobacteria,1S8TB@1236|Gammaproteobacteria,467RD@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF971) - - 5.3.1.16 ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04640 RC00945 ko00000,ko00001,ko00002,ko01000 - - - DUF971 k141_34660_11 1453501.JELR01000002_gene1255 4.42e-265 732.0 COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,1RMYV@1236|Gammaproteobacteria,464C4@72275|Alteromonadaceae 1236|Gammaproteobacteria O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis hslU GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019904,GO:0022607,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043335,GO:0043933,GO:0044085,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - ko:K03667 - - - - ko00000,ko03110 - - - AAA_2,ClpB_D2-small k141_34660_12 1279017.AQYJ01000027_gene1930 9.31e-117 336.0 COG5405@1|root,COG5405@2|Bacteria,1MVF2@1224|Proteobacteria,1RP7P@1236|Gammaproteobacteria,4643Y@72275|Alteromonadaceae 1236|Gammaproteobacteria O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery hslV GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016787,GO:0017076,GO:0019538,GO:0019904,GO:0022607,GO:0030163,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0051603,GO:0065003,GO:0070003,GO:0070011,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 3.4.25.2 ko:K01419 - - - - ko00000,ko01000,ko01002 - - - Proteasome k141_34660_14 1279017.AQYJ01000027_gene1928 5.79e-72 223.0 COG3087@1|root,COG3087@2|Bacteria,1MYFG@1224|Proteobacteria,1S9Y3@1236|Gammaproteobacteria,467S5@72275|Alteromonadaceae 1236|Gammaproteobacteria D COG3087 Cell division protein - - - ko:K03591 - - - - ko00000,ko03036 - - - SPOR k141_34660_15 1279017.AQYJ01000027_gene1927 0.0 1180.0 COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,1RPZ7@1236|Gammaproteobacteria,464GR@72275|Alteromonadaceae 1236|Gammaproteobacteria L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA priA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006276,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0010332,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042221,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0046677,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - ko:K04066 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,ResIII k141_34660_16 1453501.JELR01000002_gene1249 6.04e-43 140.0 COG0254@1|root,COG0254@2|Bacteria,1MZ69@1224|Proteobacteria,1SCMH@1236|Gammaproteobacteria,468J3@72275|Alteromonadaceae 1236|Gammaproteobacteria J Binds the 23S rRNA rpmE GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02909 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L31 k141_34660_17 1453501.JELR01000002_gene1248 5.03e-114 336.0 COG1525@1|root,COG1525@2|Bacteria,1RKRQ@1224|Proteobacteria,1S7UH@1236|Gammaproteobacteria,467WT@72275|Alteromonadaceae 1236|Gammaproteobacteria L Staphylococcal nuclease homologues - - - - - - - - - - - - SNase k141_34660_19 1279017.AQYJ01000027_gene1924 2.81e-43 146.0 2EB97@1|root,3359Q@2|Bacteria,1NBYB@1224|Proteobacteria,1SDC9@1236|Gammaproteobacteria,468XQ@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_34660_20 1042377.AFPJ01000028_gene2253 1.79e-290 804.0 COG2918@1|root,COG2918@2|Bacteria,1MW9B@1224|Proteobacteria,1RPNQ@1236|Gammaproteobacteria,464FU@72275|Alteromonadaceae 1236|Gammaproteobacteria H Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily gshA GO:0003674,GO:0003824,GO:0004357,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0008152,GO:0009058,GO:0009628,GO:0009987,GO:0010035,GO:0010038,GO:0016874,GO:0016879,GO:0016881,GO:0019184,GO:0034641,GO:0042221,GO:0042398,GO:0043043,GO:0043167,GO:0043169,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044424,GO:0044444,GO:0044464,GO:0046685,GO:0046689,GO:0046872,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0070887,GO:0071241,GO:0071243,GO:0071248,GO:0071288,GO:0071704,GO:1901564,GO:1901566,GO:1901576 6.3.2.2 ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 M00118 R00894,R10993 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - iEC042_1314.EC042_2885 Glu_cys_ligase k141_34660_21 85643.Tmz1t_1946 1.09e-36 134.0 COG3124@1|root,COG3124@2|Bacteria,1MZ59@1224|Proteobacteria,2VSFW@28216|Betaproteobacteria,2KWV1@206389|Rhodocyclales 206389|Rhodocyclales S Acyl carrier protein phosphodiesterase - - - - - - - - - - - - ACP_PD k141_34660_22 1279017.AQYJ01000027_gene1921 1.26e-99 290.0 COG1495@1|root,COG1495@2|Bacteria,1RIJE@1224|Proteobacteria,1S6WD@1236|Gammaproteobacteria,467E0@72275|Alteromonadaceae 1236|Gammaproteobacteria O Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein dsbB - - ko:K03611 - - - - ko00000,ko03110 5.A.2.1 - - DsbB k141_34660_23 1274374.CBLK010000069_gene1444 9.17e-05 47.0 COG1380@1|root,COG1380@2|Bacteria,1VEN4@1239|Firmicutes,4HNKZ@91061|Bacilli,26YZZ@186822|Paenibacillaceae 91061|Bacilli S LrgA family ywbH - - ko:K06518 - - - - ko00000,ko02000 1.E.14.2 - - LrgA k141_34660_24 1453501.JELR01000002_gene1239 1.31e-72 228.0 COG1346@1|root,COG1346@2|Bacteria,1MV81@1224|Proteobacteria,1RS5C@1236|Gammaproteobacteria,4675Y@72275|Alteromonadaceae 1236|Gammaproteobacteria M effector of murein hydrolase yohK GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - LrgB k141_34660_26 1279017.AQYJ01000027_gene1917 1.24e-121 355.0 COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,1RPMP@1236|Gammaproteobacteria,466UT@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0545 FKBP-type peptidyl-prolyl cis-trans isomerases 1 mip - 5.2.1.8 ko:K03772,ko:K03773 - - - - ko00000,ko01000,ko03110 - - - FKBP_C,FKBP_N k141_34660_28 1279017.AQYJ01000027_gene1915 1.5e-56 182.0 COG5589@1|root,COG5589@2|Bacteria,1NGHI@1224|Proteobacteria,1SGFT@1236|Gammaproteobacteria,468Z5@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF2390) - - - - - - - - - - - - DUF2390 k141_34660_30 1279017.AQYJ01000027_gene1913 9.58e-93 282.0 COG2885@1|root,COG2885@2|Bacteria 2|Bacteria M chlorophyll binding - - - - - - - - - - - - CHU_C,Calx-beta,DUF11,DUF4842,FG-GAP_2,Laminin_G_3,OMP_b-brl,PD40,TSP_3 k141_18100_1 1515746.HR45_04565 7.76e-143 412.0 COG2207@1|root,COG2207@2|Bacteria,1Q1BF@1224|Proteobacteria,1S1GE@1236|Gammaproteobacteria 1236|Gammaproteobacteria K AraC family transcriptional regulator - - - - - - - - - - - - AraC_binding_2,HTH_18 k141_18100_2 1515746.HR45_04570 2.1e-147 425.0 COG0604@1|root,COG0604@2|Bacteria,1MWBD@1224|Proteobacteria,1RPCQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - 1.6.5.5 ko:K00344 - - - - ko00000,ko01000 - - - ADH_N,ADH_zinc_N,ADH_zinc_N_2 k141_18100_3 349966.DJ58_3328 1.3e-81 250.0 COG1878@1|root,COG1878@2|Bacteria,1R8IH@1224|Proteobacteria,1S46Y@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Putative cyclase - - - - - - - - - - - - Cyclase k141_18100_4 5762.XP_002675544.1 3.3e-117 345.0 COG0010@1|root,2RZFP@2759|Eukaryota 2759|Eukaryota E Arginase family - - 3.5.3.1 ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 M00029,M00134 R00551 RC00024,RC00329 ko00000,ko00001,ko00002,ko01000 - - - Arginase k141_18100_5 339670.Bamb_3329 4.82e-162 476.0 COG1129@1|root,COG1129@2|Bacteria,1MU22@1224|Proteobacteria,2W071@28216|Betaproteobacteria,1K3FQ@119060|Burkholderiaceae 28216|Betaproteobacteria G abc transporter - - 3.6.3.17 ko:K10441 ko02010,map02010 M00212 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - ABC_tran k141_18100_6 1408322.JHYK01000001_gene1459 3.6e-16 86.3 COG4214@1|root,COG4214@2|Bacteria,1VU1F@1239|Firmicutes,24XS9@186801|Clostridia,27UE5@186928|unclassified Lachnospiraceae 186801|Clostridia G Branched-chain amino acid transport system / permease component - - - ko:K10547 ko02010,map02010 M00216 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.5 - - BPD_transp_2 k141_18100_7 1123023.JIAI01000004_gene7904 1.3e-21 101.0 COG1172@1|root,COG1172@2|Bacteria,2GMJW@201174|Actinobacteria 201174|Actinobacteria G Belongs to the binding-protein-dependent transport system permease family - - - ko:K10440 ko02010,map02010 M00212 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - BPD_transp_2 k141_18100_8 83406.HDN1F_00510 1.54e-06 57.8 COG1879@1|root,COG1879@2|Bacteria 2|Bacteria G ABC-type sugar transport system periplasmic component - - - ko:K02058,ko:K10439 ko02010,ko02030,map02010,map02030 M00212,M00221 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - Peripla_BP_4 k141_18100_9 629265.PMA4326_09480 3.66e-52 181.0 COG2207@1|root,COG2207@2|Bacteria,1Q1BF@1224|Proteobacteria,1S1GE@1236|Gammaproteobacteria,1Z9GT@136849|Pseudomonas syringae group 1236|Gammaproteobacteria K helix_turn_helix, arabinose operon control protein - - - - - - - - - - - - AraC_binding_2,HTH_18 k141_18100_10 634956.Geoth_2445 1.82e-06 57.0 COG0697@1|root,COG0697@2|Bacteria,1TRKE@1239|Firmicutes,4HE64@91061|Bacilli,1WF5C@129337|Geobacillus 91061|Bacilli EG Solute carrier family 35 - - - - - - - - - - - - EamA k141_31169_1 1123228.AUIH01000009_gene1939 2.58e-11 67.4 28HC9@1|root,2Z7P5@2|Bacteria,1R4BH@1224|Proteobacteria,1RSAN@1236|Gammaproteobacteria,1XNEQ@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_31169_2 996637.SGM_5608 5.77e-07 52.4 COG0584@1|root,COG0584@2|Bacteria,2GNM5@201174|Actinobacteria 201174|Actinobacteria C glycerophosphoryl diester phosphodiesterase glpQ - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - GDPD k141_7353_1 1116375.VEJY3_23591 6.22e-131 392.0 COG1289@1|root,COG1289@2|Bacteria,1QJEM@1224|Proteobacteria,1SMXK@1236|Gammaproteobacteria,1XUKV@135623|Vibrionales 135623|Vibrionales S Aromatic acid exporter family member 1 VPA1578 - - - - - - - - - - - FUSC k141_7353_2 1116375.VEJY3_23596 0.0 938.0 COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,1RN5K@1236|Gammaproteobacteria,1XV4P@135623|Vibrionales 135623|Vibrionales M Outer membrane efflux protein VPA1579 - - - - - - - - - - - OEP k141_7353_3 1116375.VEJY3_23601 2.1e-35 120.0 2CEDC@1|root,347N5@2|Bacteria,1P3NS@1224|Proteobacteria,1ST0W@1236|Gammaproteobacteria,1XYGB@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF1656) VPA1580 - - - - - - - - - - - DUF1656 k141_7353_4 1116375.VEJY3_23606 2.12e-195 543.0 COG1566@1|root,COG1566@2|Bacteria,1MWG0@1224|Proteobacteria,1SKG5@1236|Gammaproteobacteria,1XU0T@135623|Vibrionales 135623|Vibrionales V Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - - - - - - - - - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 k141_7353_5 1116375.VEJY3_23611 3.19e-143 406.0 COG1226@1|root,32Y28@2|Bacteria,1MYY3@1224|Proteobacteria,1S8QF@1236|Gammaproteobacteria,1XT2D@135623|Vibrionales 135623|Vibrionales P Ion channel - - - - - - - - - - - - Ion_trans_2 k141_7353_6 223926.28809985 1.2e-214 599.0 COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,1RNN1@1236|Gammaproteobacteria,1XSXA@135623|Vibrionales 135623|Vibrionales S AI-2E family transporter - - - - - - - - - - - - AI-2E_transport k141_7353_7 1116375.VEJY3_23621 1.26e-124 358.0 COG3110@1|root,COG3110@2|Bacteria,1RK33@1224|Proteobacteria,1RZRX@1236|Gammaproteobacteria,1XWDI@135623|Vibrionales 135623|Vibrionales S Belongs to the UPF0319 family SO3571 - - ko:K09909 - - - - ko00000 - - - DUF2057 k141_7353_8 1116375.VEJY3_23626 1.93e-154 436.0 COG1018@1|root,COG1018@2|Bacteria,1MW37@1224|Proteobacteria,1RR95@1236|Gammaproteobacteria,1XVIM@135623|Vibrionales 135623|Vibrionales C COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 fpr - 1.18.1.2,1.19.1.1 ko:K00528 - - R10159 - ko00000,ko01000 - - - FAD_binding_6,NAD_binding_1 k141_27507_1 1453501.JELR01000001_gene2296 6.81e-183 518.0 COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,1RN93@1236|Gammaproteobacteria,464G4@72275|Alteromonadaceae 1236|Gammaproteobacteria F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily purB - 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 - - - ASL_C,Lyase_1 k141_27507_2 1279017.AQYJ01000029_gene3822 2.01e-217 607.0 COG2850@1|root,COG2850@2|Bacteria,1MW30@1224|Proteobacteria,1RN2Q@1236|Gammaproteobacteria,464Y7@72275|Alteromonadaceae 1236|Gammaproteobacteria S A domain family that is part of the cupin metalloenzyme superfamily. ycfD GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0016491,GO:0016705,GO:0016706,GO:0018193,GO:0018195,GO:0019538,GO:0030961,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046872,GO:0046914,GO:0051213,GO:0055114,GO:0071704,GO:1901564 1.14.11.47 ko:K18850 - - - - ko00000,ko01000,ko03009 - - - Cupin_4 k141_27507_3 713586.KB900536_gene331 1.65e-33 122.0 COG2153@1|root,COG2153@2|Bacteria,1MZ86@1224|Proteobacteria,1S8SK@1236|Gammaproteobacteria 1236|Gammaproteobacteria S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases yjcF - - - - - - - - - - - Acetyltransf_10 k141_27507_4 1042377.AFPJ01000007_gene1767 7.69e-35 127.0 COG2153@1|root,COG2153@2|Bacteria,1MZ86@1224|Proteobacteria,1S8SK@1236|Gammaproteobacteria,467WF@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - - - - - - - - - - Acetyltransf_10 k141_27507_5 1453501.JELR01000001_gene2292 0.0 1167.0 COG2225@1|root,COG2225@2|Bacteria,1MVEV@1224|Proteobacteria,1RPVI@1236|Gammaproteobacteria,464G0@72275|Alteromonadaceae 1236|Gammaproteobacteria C Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA glcB GO:0000287,GO:0003674,GO:0003824,GO:0004474,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009436,GO:0009987,GO:0016054,GO:0016740,GO:0016746,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0046395,GO:0046487,GO:0046872,GO:0046912,GO:0071704,GO:0072329,GO:1901575 2.3.3.9 ko:K01638 ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200 M00012 R00472 RC00004,RC00308,RC02747 ko00000,ko00001,ko00002,ko01000 - - iECSF_1327.ECSF_2799,iECW_1372.ECW_m3242,iEKO11_1354.EKO11_0745,iWFL_1372.ECW_m3242 Malate_synthase k141_27507_6 56107.Cylst_6139 2.04e-104 318.0 COG4242@1|root,COG4242@2|Bacteria,1G325@1117|Cyanobacteria,1HJKP@1161|Nostocales 1117|Cyanobacteria PQ Belongs to the peptidase S51 family - - - - - - - - - - - - Peptidase_S51 k141_5238_1 1453501.JELR01000002_gene572 6.38e-112 330.0 2BXSN@1|root,32R1X@2|Bacteria,1MYVK@1224|Proteobacteria,1S821@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF4243) - - - - - - - - - - - - DUF4243 k141_18360_1 1121324.CLIT_10c04580 1.59e-35 130.0 COG3639@1|root,COG3639@2|Bacteria,1TQ73@1239|Firmicutes,24AGQ@186801|Clostridia 186801|Clostridia P PFAM binding-protein-dependent transport systems inner membrane component - - - ko:K02042 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - BPD_transp_1 k141_585_1 441769.ABFU01000024_gene1042 1.55e-52 167.0 COG4838@1|root,COG4838@2|Bacteria,1VAXB@1239|Firmicutes,4HKIX@91061|Bacilli,1ZI2B@1386|Bacillus 91061|Bacilli S Belongs to the UPF0358 family ylaN - - - - - - - - - - - DUF1507 k141_30064_1 218284.CCDN010000001_gene788 4.16e-91 275.0 COG0226@1|root,COG0226@2|Bacteria,1TQ5X@1239|Firmicutes,4HBEB@91061|Bacilli,1ZB22@1386|Bacillus 91061|Bacilli P Phosphate pstS GO:0003674,GO:0005488,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015698,GO:0042301,GO:0043167,GO:0043168,GO:0051179,GO:0051234 - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - PBP_like_2 k141_31317_1 1232410.KI421418_gene2304 9.44e-25 105.0 COG0077@1|root,COG0077@2|Bacteria,1MU60@1224|Proteobacteria,42MGN@68525|delta/epsilon subdivisions,2WJET@28221|Deltaproteobacteria,43SBV@69541|Desulfuromonadales 28221|Deltaproteobacteria E Prephenate dehydratase pheA - 4.2.1.51,5.4.99.5 ko:K14170 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024,M00025 R00691,R01373,R01715 RC00360,RC03116 ko00000,ko00001,ko00002,ko01000 - - - ACT,CM_2,PDT k141_37228_1 977880.RALTA_A1129 6.38e-06 50.4 COG2878@1|root,COG2878@2|Bacteria,1MUWU@1224|Proteobacteria,2VN5I@28216|Betaproteobacteria,1K1GQ@119060|Burkholderiaceae 28216|Betaproteobacteria C Part of a membrane complex involved in electron transport rnfB - - ko:K03616 - - - - ko00000 - - - FeS,Fer4_21 k141_37228_2 1453501.JELR01000001_gene3225 7.4e-20 89.4 COG4656@1|root,COG4656@2|Bacteria,1QTUI@1224|Proteobacteria,1RMIM@1236|Gammaproteobacteria,4655V@72275|Alteromonadaceae 1236|Gammaproteobacteria C Part of a membrane complex involved in electron transport rnfC GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0055114 - ko:K03615 - - - - ko00000 - - - Complex1_51K,Fer4_10,Fer4_7,Fer4_8,RnfC_N,SLBB k141_25467_1 279010.BL01782 2.17e-65 205.0 COG2323@1|root,COG2323@2|Bacteria,1UZYT@1239|Firmicutes,4HEDY@91061|Bacilli,1ZFQ1@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF421) - - - - - - - - - - - - DUF421 k141_23140_1 313612.L8106_24435 1.18e-37 135.0 COG2173@1|root,COG2173@2|Bacteria,1G56H@1117|Cyanobacteria,1HAFJ@1150|Oscillatoriales 1117|Cyanobacteria M Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide - - 3.4.13.22 ko:K08641 ko01502,ko02020,map01502,map02020 M00651 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 - - - Peptidase_M15 k141_13663_1 675817.VDA_002345 1.35e-101 311.0 COG0524@1|root,COG0524@2|Bacteria,1R52G@1224|Proteobacteria,1RN4W@1236|Gammaproteobacteria,1Y0DM@135623|Vibrionales 135623|Vibrionales G Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway - - - - - - - - - - - - HTH_DeoR,PfkB k141_586_1 665959.HMPREF1013_04163 1.49e-99 318.0 COG0737@1|root,COG0737@2|Bacteria,1TPV2@1239|Firmicutes,4HB9S@91061|Bacilli,1ZAY0@1386|Bacillus 91061|Bacilli F Belongs to the 5'-nucleotidase family - - 3.1.3.5,3.1.3.6,3.1.4.16 ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01562,R01569,R01664,R01877,R01968,R02088,R02102,R02148,R02370,R02719,R03537,R03538,R03929,R05135 RC00017,RC00078,RC00296 ko00000,ko00001,ko01000 - - - 5_nucleotid_C,Metallophos,SLH k141_32425_1 1116375.VEJY3_16486 3.48e-193 558.0 COG1129@1|root,COG4177@1|root,COG1129@2|Bacteria,COG4177@2|Bacteria,1R9IW@1224|Proteobacteria,1T36F@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Belongs to the binding-protein-dependent transport system permease family - - - ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C,BPD_transp_2 k141_32425_2 1116375.VEJY3_16491 9.53e-271 745.0 COG0402@1|root,COG0402@2|Bacteria,1MX34@1224|Proteobacteria,1RMPF@1236|Gammaproteobacteria,1XV5T@135623|Vibrionales 135623|Vibrionales F COG0402 Cytosine deaminase and related metal-dependent hydrolases codA - 3.5.4.1 ko:K01485 ko00240,ko00330,ko01100,map00240,map00330,map01100 - R00974,R01411,R02922 RC00074,RC00514,RC00809 ko00000,ko00001,ko01000 - - - Amidohydro_3 k141_32425_3 1116375.VEJY3_16496 9.85e-145 410.0 COG1802@1|root,COG1802@2|Bacteria,1R96W@1224|Proteobacteria,1RS75@1236|Gammaproteobacteria,1XUFP@135623|Vibrionales 135623|Vibrionales K COG1802 Transcriptional regulators - - - - - - - - - - - - FCD,GntR k141_32425_4 1116375.VEJY3_16501 1.98e-203 564.0 COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,1RS6U@1236|Gammaproteobacteria,1XV73@135623|Vibrionales 135623|Vibrionales K COG0583 Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_32425_5 1116375.VEJY3_16506 1.57e-157 442.0 COG1011@1|root,COG1011@2|Bacteria,1MVF8@1224|Proteobacteria,1RMK3@1236|Gammaproteobacteria,1XSVE@135623|Vibrionales 135623|Vibrionales S hydrolase (HAD superfamily) yjjG - 3.1.3.5 ko:K08723 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 k141_32425_6 1116375.VEJY3_16511 1.75e-116 334.0 COG0494@1|root,COG0494@2|Bacteria,1PC5J@1224|Proteobacteria,1S267@1236|Gammaproteobacteria,1XVIH@135623|Vibrionales 135623|Vibrionales L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - - - - - - - - - - NUDIX k141_32425_7 1116375.VEJY3_16516 6.99e-81 241.0 2BY4F@1|root,333PG@2|Bacteria,1QJW6@1224|Proteobacteria,1THXV@1236|Gammaproteobacteria,1XXV2@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_26802_2 1195246.AGRI_10071 0.0 903.0 COG0366@1|root,COG0366@2|Bacteria,1MVKX@1224|Proteobacteria,1RQHM@1236|Gammaproteobacteria,467Q9@72275|Alteromonadaceae 1236|Gammaproteobacteria G Alpha amylase, catalytic domain - - 3.2.1.133,3.2.1.135,3.2.1.20,3.2.1.54 ko:K01187,ko:K01208,ko:K21575 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00028,R00801,R00802,R02112,R03122,R06087,R06088,R11262 RC00028,RC00049,RC00077 ko00000,ko00001,ko01000 - GH13,GH31 - Alpha-amylase,Alpha-amylase_N,Cyc-maltodext_C,Cyc-maltodext_N,Malt_amylase_C k141_26802_4 1122197.ATWI01000016_gene2194 1.11e-156 450.0 COG2207@1|root,COG2207@2|Bacteria,1MX23@1224|Proteobacteria,1S1G1@1236|Gammaproteobacteria,46CNR@72275|Alteromonadaceae 1236|Gammaproteobacteria K Arabinose-binding domain of AraC transcription regulator, N-term - - - - - - - - - - - - Arabinose_bd,HTH_18 k141_26802_5 1122197.ATWI01000016_gene2193 8.68e-283 787.0 COG4257@1|root,COG4257@2|Bacteria,1R448@1224|Proteobacteria,1T0QH@1236|Gammaproteobacteria,46D13@72275|Alteromonadaceae 1236|Gammaproteobacteria V COG4257 Streptogramin lyase - - - - - - - - - - - - CarboxypepD_reg k141_26802_6 1108045.GORHZ_125_00760 7.66e-131 377.0 COG1028@1|root,COG1028@2|Bacteria,2GJU1@201174|Actinobacteria,4GAWE@85026|Gordoniaceae 201174|Actinobacteria IQ KR domain - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 k141_26802_7 1029823.AFIE01000001_gene2109 4.22e-149 428.0 COG2130@1|root,COG2130@2|Bacteria,1MUC2@1224|Proteobacteria,1RNGM@1236|Gammaproteobacteria,3NJ0W@468|Moraxellaceae 1236|Gammaproteobacteria S N-terminal domain of oxidoreductase - - - ko:K07119 - - - - ko00000 - - - ADH_N_2,ADH_zinc_N k141_26802_8 94122.Shewana3_1740 2.79e-308 883.0 COG1404@1|root,COG1404@2|Bacteria,1PE57@1224|Proteobacteria,1RWPJ@1236|Gammaproteobacteria,2QE2X@267890|Shewanellaceae 1236|Gammaproteobacteria O Belongs to the peptidase S8 family - - - - - - - - - - - - - k141_19469_1 1116375.VEJY3_19956 1.97e-153 445.0 COG4533@1|root,COG4533@2|Bacteria,1N2NK@1224|Proteobacteria,1RP2Z@1236|Gammaproteobacteria,1XUBB@135623|Vibrionales 135623|Vibrionales K transport system periplasmic component sgrR - - ko:K11925 - - - - ko00000,ko03000 - - - SBP_bac_5,SgrR_N k141_15872_1 95619.PM1_0209780 2.63e-63 209.0 COG0388@1|root,COG0388@2|Bacteria,1P8FV@1224|Proteobacteria 1224|Proteobacteria S Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source - - - - - - - - - - - - CN_hydrolase k141_15872_3 1279017.AQYJ01000021_gene2819 2.29e-207 586.0 COG3004@1|root,COG3004@2|Bacteria,1MW15@1224|Proteobacteria,1RNDE@1236|Gammaproteobacteria,464UV@72275|Alteromonadaceae 1236|Gammaproteobacteria P ) H( ) antiporter that extrudes sodium in exchange for external protons nhaA - - ko:K03313 - - - - ko00000,ko02000 2.A.33.1 - - Na_H_antiport_1,Thioredoxin_4 k141_33787_1 574376.BAMA_23000 6.09e-39 137.0 COG1451@1|root,COG1451@2|Bacteria,1V0CS@1239|Firmicutes,4HE0S@91061|Bacilli,1ZBQ8@1386|Bacillus 91061|Bacilli S WLM domain - - - ko:K07043 - - - - ko00000 - - - DUF45 k141_25468_1 42565.FP66_08845 3.83e-106 313.0 COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,1RMGZ@1236|Gammaproteobacteria,1XKY4@135619|Oceanospirillales 135619|Oceanospirillales CH D-isomer specific 2-hydroxyacid dehydrogenase - - 1.1.1.215,1.1.1.43,1.1.1.79,1.1.1.81 ko:K00032,ko:K00090 ko00030,ko00260,ko00480,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00480,map00620,map00630,map01100,map01110,map01120 - R00465,R01388,R01392,R01739,R02032,R02034 RC00001,RC00031,RC00042,RC00084 ko00000,ko00001,ko01000 - - - 2-Hacid_dh,2-Hacid_dh_C k141_34907_2 1397527.Q670_11945 1.57e-116 343.0 COG0491@1|root,COG0491@2|Bacteria,1P5NJ@1224|Proteobacteria,1S1CZ@1236|Gammaproteobacteria,1XQNR@135619|Oceanospirillales 135619|Oceanospirillales S Metallo-beta-lactamase superfamily - - 3.5.2.6 ko:K17837 ko01501,map01501 - R06363 RC01499 ko00000,ko00001,ko01000 - - - Lactamase_B k141_34907_3 1439940.BAY1663_03123 8.8e-15 71.2 COG1670@1|root,COG1670@2|Bacteria,1RCX2@1224|Proteobacteria,1S42B@1236|Gammaproteobacteria 1236|Gammaproteobacteria J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins - - 2.3.1.128 ko:K03790 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 k141_10008_2 1453501.JELR01000001_gene2487 3.66e-67 209.0 2C1GI@1|root,33B43@2|Bacteria,1NJE7@1224|Proteobacteria,1SH3D@1236|Gammaproteobacteria,468W3@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_10008_3 1453501.JELR01000001_gene2488 1e-72 221.0 COG0589@1|root,COG0589@2|Bacteria,1RHE6@1224|Proteobacteria,1S6AR@1236|Gammaproteobacteria,467I4@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0589 Universal stress protein UspA and related nucleotide-binding proteins uspA - - ko:K06149 - - - - ko00000 - - - Usp k141_10008_4 1415778.JQMM01000001_gene55 3.31e-11 66.6 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPCU@1236|Gammaproteobacteria,1J4ET@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S COG0488 ATPase components of ABC transporters with duplicated ATPase domains uup GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010528,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0031323,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0070894,GO:0071944,GO:0080090,GO:0097159,GO:1901363 - ko:K15738 - - - - ko00000,ko02000 3.A.1.120.6 - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn k141_587_1 485916.Dtox_1611 2.14e-29 112.0 COG0535@1|root,COG0535@2|Bacteria,1URM8@1239|Firmicutes,24XB8@186801|Clostridia 186801|Clostridia C 4Fe-4S single cluster domain - - - - - - - - - - - - Fer4_12,Radical_SAM,SPASM k141_587_2 370438.PTH_1002 3.26e-18 85.1 COG1018@1|root,COG3894@1|root,COG1018@2|Bacteria,COG3894@2|Bacteria,1TP0H@1239|Firmicutes,247S0@186801|Clostridia,260DA@186807|Peptococcaceae 186801|Clostridia C PFAM 2Fe-2S iron-sulfur cluster binding domain - - - - - - - - - - - - DUF4445,Fer2 k141_20611_1 42565.FP66_16045 6.27e-109 316.0 COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,1RMXF@1236|Gammaproteobacteria,1XJ8P@135619|Oceanospirillales 135619|Oceanospirillales K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair lexA - 3.4.21.88 ko:K01356 - M00729 - - ko00000,ko00002,ko01000,ko01002,ko03400 - - - LexA_DNA_bind,Peptidase_S24 k141_12504_1 42565.FP66_08630 7.44e-158 451.0 COG1362@1|root,COG1362@2|Bacteria,1NT1D@1224|Proteobacteria,1RPHR@1236|Gammaproteobacteria,1XHXD@135619|Oceanospirillales 135619|Oceanospirillales E M18 family aminopeptidase - - 3.4.11.21 ko:K01267 - - - - ko00000,ko01000,ko01002,ko04131 - - - Peptidase_M18 k141_19470_1 1294265.JCM21738_1269 6.52e-54 173.0 COG0348@1|root,COG0348@2|Bacteria,1VPU2@1239|Firmicutes,4HZRI@91061|Bacilli 91061|Bacilli C 4Fe-4S binding domain - - - - - - - - - - - - Fer4_5 k141_19470_2 1294265.JCM21738_1268 9.02e-44 144.0 COG2010@1|root,COG2010@2|Bacteria,1VG21@1239|Firmicutes,4HPNR@91061|Bacilli 91061|Bacilli C Cytochrome c - - - - - - - - - - - - Cytochrome_CBB3 k141_23142_1 1294265.JCM21738_5457 2.31e-130 379.0 COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,4H9WQ@91061|Bacilli,1ZAR7@1386|Bacillus 91061|Bacilli E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase yhaA - - ko:K01436 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 k141_7540_1 665952.HMPREF1015_01082 4.23e-52 164.0 COG4470@1|root,COG4470@2|Bacteria,1VA85@1239|Firmicutes,4HKF7@91061|Bacilli,1ZHY5@1386|Bacillus 91061|Bacilli S protein conserved in bacteria yutD - - - - - - - - - - - DUF1027 k141_7540_2 406124.ACPC01000020_gene3721 8.38e-08 56.2 2DBQ9@1|root,2ZACY@2|Bacteria,1V0WH@1239|Firmicutes,4HEH4@91061|Bacilli,1ZR7V@1386|Bacillus 91061|Bacilli S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) yutC - - - - - - - - - - - Spore_YhcN_YlaJ k141_5241_1 218284.CCDN010000008_gene4182 3.86e-134 393.0 COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,4HADT@91061|Bacilli,1ZAZA@1386|Bacillus 91061|Bacilli KT Transcriptional regulator - - - - - - - - - - - - HTH_8,PAS,PAS_9,Sigma54_activat k141_26803_1 935836.JAEL01000063_gene2150 4.69e-34 124.0 COG0614@1|root,COG0614@2|Bacteria,1TQV7@1239|Firmicutes,4HCF3@91061|Bacilli,1ZBF0@1386|Bacillus 91061|Bacilli P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component btuF - - ko:K02016 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - iYO844.BSU33180 Peripla_BP_2 k141_26803_2 1294265.JCM21738_1357 5.43e-132 377.0 COG3584@1|root,COG3584@2|Bacteria,1UYMN@1239|Firmicutes,4HIVQ@91061|Bacilli,1ZDD1@1386|Bacillus 91061|Bacilli S protein conserved in bacteria yuiC - - - - - - - - - - - 3D k141_27646_1 1122194.AUHU01000006_gene550 1.3e-37 130.0 COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,1S3RP@1236|Gammaproteobacteria,466WN@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs - - 1.3.99.16 ko:K07302 - - - - ko00000,ko01000 - - - Fer2,Fer2_2 k141_27646_2 1288826.MSNKSG1_13777 2.12e-153 456.0 COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,1RNCM@1236|Gammaproteobacteria,464YW@72275|Alteromonadaceae 1236|Gammaproteobacteria C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - - - - - - - - - - Ald_Xan_dh_C2 k141_32426_1 649747.HMPREF0083_00154 1.15e-66 209.0 28NRE@1|root,2ZBQP@2|Bacteria,1V2C0@1239|Firmicutes,4HGF6@91061|Bacilli,26XP9@186822|Paenibacillaceae 91061|Bacilli S Membrane ymcC - - - - - - - - - - - - k141_8827_1 218284.CCDN010000008_gene4134 3.1e-223 620.0 COG0448@1|root,COG0448@2|Bacteria,1TNZW@1239|Firmicutes,4HAZX@91061|Bacilli,1ZCF2@1386|Bacillus 91061|Bacilli G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans glgC GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008878,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0070566,GO:0071704,GO:1901576 2.7.7.27 ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transferase k141_8827_2 218284.CCDN010000008_gene4133 6.77e-85 268.0 COG0296@1|root,COG0296@2|Bacteria,1TP4M@1239|Firmicutes,4HAPM@91061|Bacilli,1ZCHU@1386|Bacillus 91061|Bacilli G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position glgB GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901576 2.4.1.18 ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02110 - ko00000,ko00001,ko00002,ko01000,ko04147 - CBM48,GH13 - Alpha-amylase,Alpha-amylase_C,CBM_48 k141_1584_1 1042377.AFPJ01000034_gene2328 6.44e-41 150.0 COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,1RMY0@1236|Gammaproteobacteria,4642B@72275|Alteromonadaceae 1236|Gammaproteobacteria K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released rpoN GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0042802,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - ko:K03092 ko02020,ko05111,map02020,map05111 - - - ko00000,ko00001,ko03021 - - - Sigma54_AID,Sigma54_CBD,Sigma54_DBD k141_1584_3 1453501.JELR01000001_gene3084 8.92e-70 216.0 COG1934@1|root,COG1934@2|Bacteria,1N776@1224|Proteobacteria,1RPM7@1236|Gammaproteobacteria,467V4@72275|Alteromonadaceae 1236|Gammaproteobacteria S Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm lptA GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0009279,GO:0010876,GO:0015920,GO:0016020,GO:0017089,GO:0019867,GO:0030288,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0042597,GO:0042802,GO:0044462,GO:0044464,GO:0046836,GO:0051179,GO:0051234,GO:0071702,GO:0071944,GO:1901264 - ko:K09774 - - - - ko00000,ko02000 1.B.42.1 - iB21_1397.B21_03016,iECBD_1354.ECBD_0542,iECB_1328.ECB_03065,iECD_1391.ECD_03065 OstA k141_1584_4 1279017.AQYJ01000024_gene1044 2.3e-05 45.4 COG3117@1|root,COG3117@2|Bacteria,1NGCC@1224|Proteobacteria,1SGDP@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA lptC - - ko:K11719 - - - - ko00000,ko02000 1.B.42.1 - - LptC k141_13665_1 1453501.JELR01000002_gene149 2.51e-180 505.0 COG2321@1|root,COG2321@2|Bacteria,1MU4U@1224|Proteobacteria,1RMF8@1236|Gammaproteobacteria,466BZ@72275|Alteromonadaceae 1236|Gammaproteobacteria S Putative neutral zinc metallopeptidase - - - ko:K07054 - - - - ko00000 - - - Zn_peptidase k141_4088_1 1214101.BN159_8486 1.94e-17 90.1 COG2374@1|root,COG3291@1|root,COG3568@1|root,COG2374@2|Bacteria,COG3291@2|Bacteria,COG3568@2|Bacteria 2|Bacteria N Endonuclease Exonuclease Phosphatase XK27_02140 - 3.4.21.50 ko:K01337,ko:K07004,ko:K14645 ko02024,map02024 - - - ko00000,ko00001,ko01000,ko01002,ko03110 - - - CHB_HEX_C_1,Exo_endo_phos,LTD,PKD,P_proprotein,Peptidase_S8 k141_15873_1 1267580.AF6_0425 5.18e-12 70.9 COG3039@1|root,COG3039@2|Bacteria,1TR9G@1239|Firmicutes,4HDZT@91061|Bacilli,21WBQ@150247|Anoxybacillus 91061|Bacilli L Transposase DDE domain - - - - - - - - - - - - DDE_Tnp_1_3 k141_11194_1 218284.CCDN010000009_gene4312 1.73e-106 315.0 COG3595@1|root,COG3595@2|Bacteria,1V94C@1239|Firmicutes,4HJYP@91061|Bacilli,1ZEE4@1386|Bacillus 91061|Bacilli S Putative adhesin liaG - - ko:K11621 ko02020,map02020 - - - ko00000,ko00001 - - - DUF4097 k141_588_1 1211814.CAPG01000082_gene3834 2.78e-104 325.0 COG1948@1|root,COG4880@2|Bacteria,1TQK0@1239|Firmicutes,4H9YF@91061|Bacilli,1ZDVB@1386|Bacillus 91061|Bacilli L Beta propeller domain - - - - - - - - - - - - Beta_propel,Big_5,Cu_amine_oxidN1 k141_13666_1 796606.BMMGA3_12325 1.4e-81 243.0 COG1490@1|root,COG1490@2|Bacteria,1V6GH@1239|Firmicutes,4HINN@91061|Bacilli,1ZG82@1386|Bacillus 91061|Bacilli J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality dtd GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - ko:K07560 - - - - ko00000,ko01000,ko03016 - - - Tyr_Deacylase k141_28967_1 1294265.JCM21738_1253 4.93e-73 230.0 COG1366@1|root,COG1366@2|Bacteria,1UNBX@1239|Firmicutes,4HEFW@91061|Bacilli,1ZAYN@1386|Bacillus 91061|Bacilli T Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor) - - - ko:K17763 - - - - ko00000,ko03021 - - - STAS k141_34909_1 1034347.CAHJ01000062_gene977 1.74e-148 433.0 COG0277@1|root,COG0277@2|Bacteria,1TQMR@1239|Firmicutes,4HDHV@91061|Bacilli,1ZEDC@1386|Bacillus 91061|Bacilli C FAD binding domain - - - ko:K11472 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001 - - - FAD-oxidase_C,FAD_binding_4 k141_12505_1 1265313.HRUBRA_00575 1.69e-37 128.0 COG3245@1|root,COG3245@2|Bacteria,1MZBZ@1224|Proteobacteria,1S9Z9@1236|Gammaproteobacteria,1JAYT@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C COG3245 Cytochrome c5 cyc - 1.9.3.1 ko:K02277 ko00190,ko01100,map00190,map01100 M00155 - - ko00000,ko00001,ko00002,ko01000 3.D.4.4 - - Cytochrome_CBB3 k141_589_1 935837.JAEK01000011_gene166 6.4e-54 181.0 28MSG@1|root,2ZB0U@2|Bacteria,1TT1H@1239|Firmicutes,4HBNQ@91061|Bacilli,1ZCHW@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2515) yppC - - - - - - - - - - - DUF2515 k141_7541_1 1453501.JELR01000001_gene1880 9.29e-54 183.0 COG0069@1|root,COG0069@2|Bacteria,1MU7B@1224|Proteobacteria,1RP1C@1236|Gammaproteobacteria,46481@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the glutamate synthase family - - - - - - - - - - - - Glu_synthase k141_7541_2 1042377.AFPJ01000037_gene2956 3.29e-21 91.7 COG1533@1|root,COG1533@2|Bacteria,1MW0H@1224|Proteobacteria,1RQNF@1236|Gammaproteobacteria,465H5@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG1533 DNA repair photolyase - - - - - - - - - - - - Radical_SAM k141_37230_1 1294265.JCM21738_4242 3.79e-174 497.0 COG0488@1|root,COG0488@2|Bacteria,1TPW0@1239|Firmicutes,4HATH@91061|Bacilli,1ZBVV@1386|Bacillus 91061|Bacilli S COG0488 ATPase components of ABC transporters with duplicated ATPase domains ykpA - - - - - - - - - - - ABC_tran,ABC_tran_Xtn k141_12506_1 218284.CCDN010000001_gene949 3.02e-96 283.0 29VNZ@1|root,30H6A@2|Bacteria,1V5PG@1239|Firmicutes,4HJV5@91061|Bacilli,1ZBD8@1386|Bacillus 91061|Bacilli S Conserved membrane protein YqhR yqhR - - - - - - - - - - - YqhR k141_30085_1 1051646.VITU9109_15953 1.24e-148 431.0 COG1012@1|root,COG1012@2|Bacteria,1MUHV@1224|Proteobacteria,1RNFN@1236|Gammaproteobacteria,1XTUN@135623|Vibrionales 135623|Vibrionales C COG1012 NAD-dependent aldehyde dehydrogenases - - 1.2.1.18,1.2.1.27 ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 M00013 R00705,R00706,R00922,R00935 RC00004,RC02723,RC02817 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_30085_2 1517681.HW45_09880 8.53e-238 658.0 COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,1RMVU@1236|Gammaproteobacteria,1XVD1@135623|Vibrionales 135623|Vibrionales C Iron-containing alcohol dehydrogenase - - - - - - - - - - - - Fe-ADH k141_19495_2 1279017.AQYJ01000024_gene913 3.07e-51 162.0 COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,1S9DN@1236|Gammaproteobacteria,467WN@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG0760 Parvulin-like peptidyl-prolyl isomerase ppiC - 5.2.1.8 ko:K03769 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_3 k141_26849_1 1279017.AQYJ01000026_gene36 3.21e-110 332.0 COG0008@1|root,COG0008@2|Bacteria,1MUC8@1224|Proteobacteria,1RQ7G@1236|Gammaproteobacteria,464TJ@72275|Alteromonadaceae 1236|Gammaproteobacteria J COG0008 Glutamyl- and glutaminyl-tRNA synthetases glnS GO:0003674,GO:0003824,GO:0004812,GO:0004819,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006425,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.18 ko:K01886 ko00970,ko01100,map00970,map01100 M00359,M00360 R03652 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iECIAI39_1322.ECIAI39_0637 tRNA-synt_1c,tRNA-synt_1c_C k141_34950_2 1279017.AQYJ01000022_gene2673 1.17e-35 131.0 COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,1RQWA@1236|Gammaproteobacteria,467MP@72275|Alteromonadaceae 1236|Gammaproteobacteria D Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division cpoB GO:0005575,GO:0005623,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043933,GO:0044085,GO:0044464,GO:0051259,GO:0051260,GO:0051301,GO:0065003,GO:0071840 - - - - - - - - - - TPR_16,TPR_6,TolA_bind_tri k141_13689_3 1279017.AQYJ01000023_gene3216 0.0 978.0 COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,1RN5I@1236|Gammaproteobacteria,469UF@72275|Alteromonadaceae 1236|Gammaproteobacteria C Aconitase C-terminal domain - - 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_C k141_8854_1 309801.trd_0986 1.97e-131 384.0 COG0050@1|root,COG0050@2|Bacteria,2G5KI@200795|Chloroflexi,27XXD@189775|Thermomicrobia 189775|Thermomicrobia J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis - - - ko:K02358 - - - - ko00000,ko03012,ko03029,ko04147 - - - GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 k141_10055_1 269800.Tfu_1411 3.62e-11 68.6 COG1165@1|root,COG1165@2|Bacteria,2GMEB@201174|Actinobacteria,4EFPH@85012|Streptosporangiales 201174|Actinobacteria H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) menD GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 2.2.1.9 ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R08165 RC02186 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_N k141_17090_1 218284.CCDN010000001_gene1525 6.6e-66 204.0 2EARW@1|root,334U0@2|Bacteria,1VIDH@1239|Firmicutes,4HPDQ@91061|Bacilli,1ZIUM@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_21869_1 1294265.JCM21738_3731 9.44e-36 125.0 COG0097@1|root,COG0097@2|Bacteria,1V1FC@1239|Firmicutes,4HFQD@91061|Bacilli,1ZCR5@1386|Bacillus 91061|Bacilli J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center rplF GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02933 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L6 k141_21869_3 315749.Bcer98_0117 4.27e-39 129.0 COG0199@1|root,COG0199@2|Bacteria,1VEF6@1239|Firmicutes,4HNKX@91061|Bacilli,1ZHVE@1386|Bacillus 91061|Bacilli J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site rpsN GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02954 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S14 k141_32435_1 1408423.JHYA01000004_gene2336 3.67e-23 104.0 COG0373@1|root,COG0373@2|Bacteria,1TQN9@1239|Firmicutes,4H34I@909932|Negativicutes 909932|Negativicutes H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) hemA - 1.2.1.70 ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R04109 RC00055,RC00149 ko00000,ko00001,ko00002,ko01000 - - - GlutR_N,GlutR_dimer,Shikimate_DH k141_12551_1 218284.CCDN010000010_gene4339 7.36e-199 553.0 COG0202@1|root,COG0202@2|Bacteria,1TPR8@1239|Firmicutes,4H9R1@91061|Bacilli,1ZBHX@1386|Bacillus 91061|Bacilli K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoA GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L k141_25499_1 218284.CCDN010000002_gene2008 1.06e-131 383.0 COG0505@1|root,COG0505@2|Bacteria,1TQ8N@1239|Firmicutes,4HAYC@91061|Bacilli,1ZBBD@1386|Bacillus 91061|Bacilli F Carbamoyl-phosphate synthetase glutamine chain carA GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_sm_chain,GATase k141_11226_1 42565.FP66_01995 4.32e-12 64.7 COG1344@1|root,COG1344@2|Bacteria,1PJUJ@1224|Proteobacteria,1RPNR@1236|Gammaproteobacteria 1236|Gammaproteobacteria N Belongs to the bacterial flagellin family flgL GO:0005575,GO:0005576,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - ko:K02397 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flagellin_C,Flagellin_N k141_11226_2 42565.FP66_01990 2.99e-111 325.0 COG1684@1|root,COG1684@2|Bacteria,1NIF4@1224|Proteobacteria,1RMYW@1236|Gammaproteobacteria,1XJFX@135619|Oceanospirillales 135619|Oceanospirillales N Role in flagellar biosynthesis fliR - - ko:K02421 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - Bac_export_1 k141_10056_1 1211814.CAPG01000056_gene2795 2.71e-35 128.0 COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,4HA4N@91061|Bacilli,1ZBDJ@1386|Bacillus 91061|Bacilli C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family trxB - 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Pyr_redox_2 k141_31336_1 1385511.N783_20875 1.18e-19 92.4 COG3583@1|root,COG3584@1|root,COG3583@2|Bacteria,COG3584@2|Bacteria,1TTIK@1239|Firmicutes,4HC79@91061|Bacilli,2Y8QI@289201|Pontibacillus 91061|Bacilli S G5 yabE - - - - - - - - - - - 3D,DUF348,G5 k141_14950_3 1141136.K4F774_9CAUD 2.58e-23 90.9 4QBNW@10239|Viruses,4QXIZ@35237|dsDNA viruses no RNA stage,4QTQP@28883|Caudovirales,4QJWG@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k141_23489_1 218284.CCDN010000007_gene3911 2.54e-09 58.2 COG1292@1|root,COG1292@2|Bacteria,1TRS6@1239|Firmicutes,4HA7U@91061|Bacilli,1ZBRN@1386|Bacillus 91061|Bacilli M Belongs to the BCCT transporter (TC 2.A.15) family opuD_3 - - - - - - - - - - - BCCT k141_23489_2 218284.CCDN010000007_gene3912 9.86e-122 353.0 COG0561@1|root,COG0561@2|Bacteria,1V5FB@1239|Firmicutes,4HGY8@91061|Bacilli,1ZDBI@1386|Bacillus 91061|Bacilli S hydrolases of the HAD superfamily ycsE - - - - - - - - - - - Hydrolase_3 k141_30291_1 1234364.AMSF01000085_gene2873 1.4e-05 45.8 COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RMFF@1236|Gammaproteobacteria,1X3MV@135614|Xanthomonadales 135614|Xanthomonadales C dehydrogenase lpdA - 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim k141_30291_2 153948.NAL212_0468 4.84e-29 116.0 COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,2VJ9R@28216|Betaproteobacteria,372ES@32003|Nitrosomonadales 28216|Betaproteobacteria P TIGRFAM Sodium sulphate symporter - - - ko:K11106,ko:K14445 - - - - ko00000,ko02000 2.A.47.1,2.A.47.3.3 - - Na_sulph_symp k141_5654_1 997296.PB1_00160 3.94e-46 160.0 2BVKZ@1|root,32QXU@2|Bacteria,1V93P@1239|Firmicutes,4HJKD@91061|Bacilli,1ZH6C@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_5654_2 1123252.ATZF01000027_gene1605 2.45e-17 75.9 2CDF4@1|root,32RXN@2|Bacteria,1VACE@1239|Firmicutes,4HKM4@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF1360) - - - - - - - - - - - - DUF1360 k141_14082_1 218284.CCDN010000002_gene2334 1.09e-22 97.8 COG4632@1|root,COG4632@2|Bacteria,1UV25@1239|Firmicutes,4I5JA@91061|Bacilli,1ZEFI@1386|Bacillus 91061|Bacilli G Phosphodiester glycosidase - - - - - - - - - - - - NAGPA,SPOR k141_22154_1 218284.CCDN010000002_gene2485 2.43e-44 156.0 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli,1ZAY9@1386|Bacillus 91061|Bacilli C Belongs to the aldehyde dehydrogenase family - - 1.2.1.32,1.2.1.85 ko:K10217 ko00362,ko00380,ko00622,ko01100,ko01120,ko01220,map00362,map00380,map00622,map01100,map01120,map01220 M00038,M00569 R02762,R03889,R05353 RC00218,RC00254 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_22154_2 218284.CCDN010000002_gene2484 1.54e-98 287.0 COG0251@1|root,COG0251@2|Bacteria,1V6G4@1239|Firmicutes,4HHIF@91061|Bacilli,1ZGKI@1386|Bacillus 91061|Bacilli J endoribonuclease L-PSP - - - - - - - - - - - - YjgF_endoribonc k141_22154_3 218284.CCDN010000002_gene2483 9.22e-60 192.0 COG2159@1|root,COG2159@2|Bacteria,1UXYD@1239|Firmicutes,4HDAD@91061|Bacilli,1ZDX2@1386|Bacillus 91061|Bacilli S Amidohydrolase - - 4.1.1.45,4.1.1.52 ko:K03392,ko:K22213 ko00380,ko01100,map00380,map01100 M00038 R04323 RC00779 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_2 k141_11602_1 997296.PB1_03145 2.19e-108 343.0 COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,4HA3G@91061|Bacilli,1ZAVY@1386|Bacillus 91061|Bacilli T Diguanylate cyclase - - - - - - - - - - - - EAL,FIST,FIST_C,GAF_2,GGDEF,PAS,PAS_4,PAS_9,dCache_1 k141_7826_1 1279017.AQYJ01000021_gene2855 1.25e-134 392.0 COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,1RQDA@1236|Gammaproteobacteria,465PG@72275|Alteromonadaceae 1236|Gammaproteobacteria T Histidine kinase yesM - 2.7.13.3 ko:K08082 ko02020,map02020 M00493 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,His_kinase k141_24568_1 218284.CCDN010000004_gene3127 8.24e-69 219.0 COG0044@1|root,COG0044@2|Bacteria,1TPI6@1239|Firmicutes,4HAA9@91061|Bacilli,1ZE4P@1386|Bacillus 91061|Bacilli F Catalyzes the hydrolytic cleavage of a subset of L- isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation iadA - - ko:K01305 - - - - ko00000,ko01000,ko01002 - - - Amidohydro_1,Amidohydro_3 k141_37479_5 1051646.VITU9109_01017 1.12e-217 602.0 COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,1RNIR@1236|Gammaproteobacteria,1XTK6@135623|Vibrionales 135623|Vibrionales I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids fabH GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACP_syn_III,ACP_syn_III_C k141_37479_6 674977.VMC_28410 2.87e-229 634.0 COG0416@1|root,COG0416@2|Bacteria,1MVM3@1224|Proteobacteria,1RM7R@1236|Gammaproteobacteria,1XU27@135623|Vibrionales 135623|Vibrionales I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA plsX GO:0003674,GO:0003824,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0044238,GO:0071704,GO:1901576 2.3.1.15 ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FA_synthesis k141_37479_7 1280001.BAOA01000086_gene3566 3.76e-31 109.0 COG0333@1|root,COG0333@2|Bacteria,1N6RF@1224|Proteobacteria,1SC9G@1236|Gammaproteobacteria,1XYWA@135623|Vibrionales 135623|Vibrionales J Belongs to the bacterial ribosomal protein bL32 family rpmF GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02911 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_L32p k141_37479_8 1116375.VEJY3_10710 2.82e-115 331.0 COG1399@1|root,COG1399@2|Bacteria,1PGKW@1224|Proteobacteria,1RRK3@1236|Gammaproteobacteria,1XTCK@135623|Vibrionales 135623|Vibrionales S metal-binding, possibly nucleic acid-binding protein yceD - - ko:K07040 - - - - ko00000 - - - DUF177 k141_23528_1 1279017.AQYJ01000020_gene1363 4.34e-32 119.0 COG1595@1|root,COG1595@2|Bacteria,1N748@1224|Proteobacteria,1SEDH@1236|Gammaproteobacteria,468VM@72275|Alteromonadaceae 1236|Gammaproteobacteria K ECF sigma factor - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_4295_1 203124.Tery_4367 0.000985 48.1 2EDIY@1|root,337EU@2|Bacteria,1GEPN@1117|Cyanobacteria,1HFUN@1150|Oscillatoriales 1117|Cyanobacteria - - - - - - - - - - - - - - - k141_4295_2 338966.Ppro_3373 5.47e-27 121.0 COG1639@1|root,COG2199@1|root,COG1639@2|Bacteria,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,42PVX@68525|delta/epsilon subdivisions,2WIJ8@28221|Deltaproteobacteria 28221|Deltaproteobacteria T PFAM GGDEF domain containing protein - - - - - - - - - - - - GAF_2,GGDEF k141_4295_3 1122169.AREN01000005_gene1922 3.88e-41 168.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1JDHN@118969|Legionellales 118969|Legionellales T Putative diguanylate phosphodiesterase - - - - - - - - - - - - EAL,GGDEF k141_4295_4 1116375.VEJY3_17091 5.65e-141 399.0 COG1309@1|root,COG1309@2|Bacteria,1R4DQ@1224|Proteobacteria,1SYK0@1236|Gammaproteobacteria,1Y2W7@135623|Vibrionales 135623|Vibrionales K YcdC-like protein, C-terminal region - - - ko:K09017 - - - - ko00000,ko03000 - - - TetR_C_3,TetR_N k141_4295_5 1116375.VEJY3_17086 1.88e-307 842.0 COG4630@1|root,COG4630@2|Bacteria,1MWI1@1224|Proteobacteria,1RQ5C@1236|Gammaproteobacteria,1XV1K@135623|Vibrionales 135623|Vibrionales F COG4630 Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A xdhA - 1.17.1.4 ko:K13481 ko00230,ko01100,ko01120,map00230,map01100,map01120 M00546 R01768,R02103 RC00143 ko00000,ko00001,ko00002,ko01000 - - - CO_deh_flav_C,FAD_binding_5,Fer2,Fer2_2 k141_4295_6 1116375.VEJY3_17081 0.0 1462.0 COG4631@1|root,COG4631@2|Bacteria,1NQSR@1224|Proteobacteria,1T1HI@1236|Gammaproteobacteria,1XTF2@135623|Vibrionales 135623|Vibrionales F COG4631 Xanthine dehydrogenase, molybdopterin-binding subunit B xdhB - 1.17.1.4 ko:K13482 ko00230,ko01100,ko01120,map00230,map01100,map01120 M00546 R01768,R02103 RC00143 ko00000,ko00001,ko00002,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 k141_4295_7 1116375.VEJY3_17076 2.93e-177 498.0 COG1975@1|root,COG1975@2|Bacteria,1R3RT@1224|Proteobacteria,1RQNB@1236|Gammaproteobacteria,1XVQ0@135623|Vibrionales 135623|Vibrionales O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family xdhC - - ko:K07402 - - - - ko00000 - - - XdhC_C,XdhC_CoxI k141_4295_8 1116375.VEJY3_17071 1.64e-95 280.0 COG3195@1|root,COG3195@2|Bacteria,1RIGR@1224|Proteobacteria,1S6QX@1236|Gammaproteobacteria,1Y0YQ@135623|Vibrionales 135623|Vibrionales S OHCU decarboxylase - - 4.1.1.97 ko:K16840 ko00230,ko01100,ko01120,map00230,map01100,map01120 M00546 R06604 RC01551 ko00000,ko00001,ko00002,ko01000 - - - OHCU_decarbox k141_4295_9 1116375.VEJY3_17066 2.43e-68 207.0 COG2351@1|root,COG2351@2|Bacteria,1RH84@1224|Proteobacteria,1SC8E@1236|Gammaproteobacteria,1XXSH@135623|Vibrionales 135623|Vibrionales S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily - - 3.5.2.17 ko:K07127 ko00230,ko01100,ko01120,map00230,map01100,map01120 M00546 R06601 RC03393 ko00000,ko00001,ko00002,ko01000,ko02000 9.B.35.1.2,9.B.35.2 - - Transthyretin k141_4295_10 1116375.VEJY3_17061 3.71e-137 396.0 COG3748@1|root,COG3748@2|Bacteria,1MWHB@1224|Proteobacteria,1RRV4@1236|Gammaproteobacteria,1XUPI@135623|Vibrionales 135623|Vibrionales S Urate oxidase N-terminal - - - - - - - - - - - - Urate_ox_N k141_27209_1 1294265.JCM21738_3691 3.66e-36 130.0 COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,4HAMZ@91061|Bacilli,1ZB13@1386|Bacillus 91061|Bacilli C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit atpA - 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - iSB619.SA_RS10975 ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N k141_27209_2 1294265.JCM21738_3692 1.87e-57 185.0 COG0224@1|root,COG0224@2|Bacteria,1TPBX@1239|Firmicutes,4HB0E@91061|Bacilli,1ZCKT@1386|Bacillus 91061|Bacilli C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex atpG - - ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - iSB619.SA_RS10970,iYO844.BSU36820 ATP-synt k141_7856_1 1116375.VEJY3_23006 0.0 932.0 COG2072@1|root,COG2072@2|Bacteria,1MU71@1224|Proteobacteria,1RP8X@1236|Gammaproteobacteria 1236|Gammaproteobacteria P flavoprotein involved in K transport - - - - - - - - - - - - FMO-like,NAD_binding_8,Pyr_redox_3 k141_35319_1 358681.BBR47_28200 2.09e-44 153.0 COG0384@1|root,COG0384@2|Bacteria,1UJBU@1239|Firmicutes,4ITD3@91061|Bacilli,26V97@186822|Paenibacillaceae 91061|Bacilli S phenazine biosynthesis protein PhzF - - - - - - - - - - - - - k141_24595_2 1042377.AFPJ01000008_gene1958 1.13e-154 442.0 COG2850@1|root,COG2850@2|Bacteria,1MUAC@1224|Proteobacteria,1RQQP@1236|Gammaproteobacteria,465RI@72275|Alteromonadaceae 1236|Gammaproteobacteria S Cupin-like domain - - - - - - - - - - - - Cupin_8 k141_18801_1 42565.FP66_08765 3.95e-48 156.0 COG0054@1|root,COG0054@2|Bacteria,1RHCZ@1224|Proteobacteria,1S73F@1236|Gammaproteobacteria,1XK6V@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin - - 2.5.1.78 ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R04457 RC00960 ko00000,ko00001,ko00002,ko01000 - - - DMRL_synthase k141_23529_1 1294265.JCM21738_141 1.19e-135 386.0 COG2120@1|root,COG2120@2|Bacteria,1TV10@1239|Firmicutes,4HFJQ@91061|Bacilli,1ZAZI@1386|Bacillus 91061|Bacilli S proteins, LmbE homologs ypjG - - ko:K01463 - - - - ko00000,ko01000 - - - PIG-L k141_19839_1 935837.JAEK01000023_gene1226 1.38e-19 85.1 COG0745@1|root,COG0745@2|Bacteria,1TS8Z@1239|Firmicutes,4HC86@91061|Bacilli,1ZB3W@1386|Bacillus 91061|Bacilli KT COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - - - - - - - - - - Response_reg,Trans_reg_C k141_3066_1 406124.ACPC01000047_gene1752 3.27e-99 302.0 COG1292@1|root,COG1292@2|Bacteria,1TRS6@1239|Firmicutes,4HA7U@91061|Bacilli,1ZBRN@1386|Bacillus 91061|Bacilli M Belongs to the BCCT transporter (TC 2.A.15) family - - - ko:K05020 - - - - ko00000,ko02000 2.A.15.1.1,2.A.15.1.11 - - BCCT k141_27210_1 218284.CCDN010000001_gene1187 6.93e-111 335.0 COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,4HA2X@91061|Bacilli,1ZCFH@1386|Bacillus 91061|Bacilli F Belongs to the formate--tetrahydrofolate ligase family fhs GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.3 ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R00943 RC00026,RC00111 ko00000,ko00001,ko00002,ko01000 - - - FTHFS k141_5676_1 218284.CCDN010000005_gene3327 9.21e-131 377.0 COG1028@1|root,COG1028@2|Bacteria,1TQZW@1239|Firmicutes,4HAS8@91061|Bacilli,1ZBWH@1386|Bacillus 91061|Bacilli IQ Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short k141_37480_1 42565.FP66_06770 5.08e-64 210.0 COG2334@1|root,COG2334@2|Bacteria,1QV5C@1224|Proteobacteria,1T293@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Ecdysteroid kinase - - - - - - - - - - - - APH k141_34075_1 1121939.L861_11875 9.11e-80 249.0 COG3203@1|root,COG3203@2|Bacteria,1N04Q@1224|Proteobacteria,1RWKD@1236|Gammaproteobacteria,1XMC3@135619|Oceanospirillales 135619|Oceanospirillales M Porin Gram-negative type - - - ko:K09476 ko01501,ko02020,map01501,map02020 M00746 - - ko00000,ko00001,ko00002,ko01504,ko02000 1.B.1.1.1 - - Porin_4 k141_10398_1 218284.CCDN010000005_gene3253 2.69e-29 111.0 COG1028@1|root,COG1028@2|Bacteria,1TR53@1239|Firmicutes,4HB8Y@91061|Bacilli,1ZAS0@1386|Bacillus 91061|Bacilli IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) yhxC - - - - - - - - - - - adh_short_C2 k141_18802_1 218284.CCDN010000006_gene3671 1.62e-102 305.0 COG2021@1|root,COG2021@2|Bacteria,1TQSV@1239|Firmicutes,4HBNC@91061|Bacilli,1ZEVF@1386|Bacillus 91061|Bacilli E Belongs to the AB hydrolase superfamily. MetX family metXA GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 ko:K00641 ko00270,ko01100,ko01130,map00270,map01100,map01130 - R01776 RC00004,RC00041 ko00000,ko00001,ko01000 - - - Abhydrolase_1 k141_7857_1 218284.CCDN010000001_gene1895 3.84e-110 327.0 COG0750@1|root,COG0750@2|Bacteria,1TPMC@1239|Firmicutes,4HAQ5@91061|Bacilli,1ZCPQ@1386|Bacillus 91061|Bacilli M zinc metalloprotease rasP - - ko:K11749 ko02024,ko04112,map02024,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - PDZ_2,Peptidase_M50 k141_24596_1 218284.CCDN010000008_gene4180 3.36e-46 159.0 COG0477@1|root,COG2814@2|Bacteria,1TPJ6@1239|Firmicutes,4HAGJ@91061|Bacilli,1ZBPE@1386|Bacillus 91061|Bacilli EGP Major facilitator superfamily yttB - - - - - - - - - - - MFS_1 k141_4296_1 1196031.ALEG01000020_gene3040 1.4e-29 112.0 COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,4HAB1@91061|Bacilli,1ZBQ5@1386|Bacillus 91061|Bacilli P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system pstB - 3.6.3.27 ko:K02036 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 - iSB619.SA_RS06920 ABC_tran k141_4296_2 1307436.PBF_21723 1.87e-67 211.0 COG0581@1|root,COG0581@2|Bacteria,1TP74@1239|Firmicutes,4HAKF@91061|Bacilli,1ZDAY@1386|Bacillus 91061|Bacilli P Phosphate transport system permease pstA - - ko:K02038 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 k141_1859_1 861299.J421_2629 2.7e-77 244.0 COG0055@1|root,COG0055@2|Bacteria,1ZSNP@142182|Gemmatimonadetes 142182|Gemmatimonadetes C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits atpD - 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_N k141_14118_1 1453501.JELR01000002_gene116 2.78e-175 514.0 COG1629@1|root,COG4771@2|Bacteria,1MUNK@1224|Proteobacteria,1RN9S@1236|Gammaproteobacteria,464ZY@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_14118_3 466088.CL42_06635 3.57e-48 166.0 COG1853@1|root,COG1853@2|Bacteria,1RGYM@1224|Proteobacteria,1RSQV@1236|Gammaproteobacteria,3NIZ4@468|Moraxellaceae 1236|Gammaproteobacteria S Flavin reductase like domain C1-hpah - - - - - - - - - - - Flavin_Reduct k141_14118_4 1279017.AQYJ01000024_gene938 5.99e-114 344.0 COG0446@1|root,COG1773@1|root,COG0446@2|Bacteria,COG1773@2|Bacteria,1NR3M@1224|Proteobacteria,1RQ07@1236|Gammaproteobacteria,46561@72275|Alteromonadaceae 1236|Gammaproteobacteria C NAD(FAD)-dependent dehydrogenases rubB - 1.18.1.1 ko:K05297 ko00071,map00071 - R02000 - ko00000,ko00001,ko01000 - - - Pyr_redox_2,Rubredoxin k141_32756_1 1033802.SSPSH_003255 1.19e-73 239.0 COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,1RMXX@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane murJ GO:0000270,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0006869,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0010876,GO:0015647,GO:0015648,GO:0015835,GO:0015836,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0030203,GO:0031224,GO:0031226,GO:0033036,GO:0034203,GO:0034204,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0046836,GO:0051179,GO:0051234,GO:0055085,GO:0061024,GO:0065007,GO:0065008,GO:0070589,GO:0071554,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0071944,GO:0097035,GO:1901135,GO:1901137,GO:1901264,GO:1901505,GO:1901564,GO:1901566,GO:1901576 - ko:K03980 - - - - ko00000,ko01011,ko02000 2.A.66.4 - iECO103_1326.ECO103_1114 MVIN k141_18803_1 768066.HELO_1263 4.48e-83 271.0 COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,1RMS9@1236|Gammaproteobacteria,1XHCH@135619|Oceanospirillales 135619|Oceanospirillales L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate uvrA - - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran k141_30313_1 1088721.NSU_2724 5.37e-11 68.6 COG4774@1|root,COG4774@2|Bacteria,1PIT1@1224|Proteobacteria,2TR52@28211|Alphaproteobacteria,2K2XI@204457|Sphingomonadales 204457|Sphingomonadales P TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_7858_1 1453501.JELR01000001_gene2490 3.36e-16 79.3 COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,1RMS8@1236|Gammaproteobacteria,4657M@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) slt GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009274,GO:0016740,GO:0016757,GO:0030203,GO:0030288,GO:0030312,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - ko:K08309 - - - - ko00000,ko01000,ko01011 - GH23 iETEC_1333.ETEC_4747,iPC815.YPO0452 SLT,SLT_L k141_7858_2 1121456.ATVA01000012_gene2549 2.19e-13 70.5 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42MMK@68525|delta/epsilon subdivisions,2WJC1@28221|Deltaproteobacteria,2M8SI@213115|Desulfovibrionales 28221|Deltaproteobacteria S PFAM ABC transporter related uup - - ko:K15738 - - - - ko00000,ko02000 3.A.1.120.6 - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn k141_23530_2 1196031.ALEG01000020_gene3041 1.46e-23 96.3 COG0704@1|root,COG0704@2|Bacteria,1URN3@1239|Firmicutes,4HEU9@91061|Bacilli,1ZDDZ@1386|Bacillus 91061|Bacilli P Plays a role in the regulation of phosphate uptake phoU - - ko:K02039 - - - - ko00000 - - - PhoU k141_19841_1 1196028.ALEF01000050_gene3486 1.48e-17 80.5 COG3448@1|root,COG3448@2|Bacteria,1UIKE@1239|Firmicutes,4ISMB@91061|Bacilli,4C579@84406|Virgibacillus 91061|Bacilli T Domain in cystathionine beta-synthase and other proteins. - - - ko:K04767 - - - - ko00000 - - - ACT,CBS k141_22195_2 1453501.JELR01000002_gene904 5.19e-150 433.0 COG3515@1|root,COG3515@2|Bacteria,1MY80@1224|Proteobacteria,1T0A1@1236|Gammaproteobacteria,466QN@72275|Alteromonadaceae 1236|Gammaproteobacteria S ImpA, N-terminal, type VI secretion system impA - - ko:K11902 ko02025,map02025 M00334 - - ko00000,ko00001,ko00002,ko02044 - - - ImpA_N k141_24597_1 1123236.KB899378_gene1686 4.41e-128 371.0 COG4948@1|root,COG4948@2|Bacteria,1MW76@1224|Proteobacteria,1RMKS@1236|Gammaproteobacteria,466KF@72275|Alteromonadaceae 1236|Gammaproteobacteria M Mandelate racemase / muconate lactonizing enzyme, C-terminal domain ycjG GO:0003674,GO:0003824,GO:0016853,GO:0016854,GO:0016855 5.1.1.20,5.5.1.1 ko:K01856,ko:K19802 ko00361,ko00362,ko00364,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00364,map00623,map01100,map01120,map01220 M00568 R05300,R05390,R06989,R08116,R09229,R10938 RC00903,RC01038,RC01108,RC01321,RC01356,RC03309 ko00000,ko00001,ko00002,ko01000 - - iEC042_1314.EC042_1441,iECUMN_1333.ECUMN_1620 MR_MLE_C,MR_MLE_N k141_5677_1 1042377.AFPJ01000009_gene273 1.57e-124 362.0 COG0697@1|root,COG0697@2|Bacteria,1QSKQ@1224|Proteobacteria,1RYG1@1236|Gammaproteobacteria,466BE@72275|Alteromonadaceae 1236|Gammaproteobacteria EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - ko:K07052 - - - - ko00000 - - - EamA k141_31460_1 1294265.JCM21738_76 7.51e-60 184.0 2E34J@1|root,32Y4N@2|Bacteria,1VESM@1239|Firmicutes,4HKID@91061|Bacilli,1ZI8X@1386|Bacillus 91061|Bacilli S CotJB protein cotJB - - ko:K06333 - - - - ko00000 - - - CotJB k141_31460_2 1294265.JCM21738_75 1.93e-73 220.0 COG3546@1|root,COG3546@2|Bacteria,1TQVQ@1239|Firmicutes,4HA34@91061|Bacilli,1ZQQY@1386|Bacillus 91061|Bacilli P Spore Coat cotJC - - ko:K06334 - - - - ko00000 - - - Mn_catalase k141_18804_1 1294265.JCM21738_2995 1.82e-47 159.0 COG2510@1|root,COG2510@2|Bacteria,1V3VG@1239|Firmicutes,4HP13@91061|Bacilli,1ZDV1@1386|Bacillus 91061|Bacilli S EamA-like transporter family - - - ko:K08978 - - - - ko00000,ko02000 2.A.7.2 - - EamA k141_14119_1 218284.CCDN010000006_gene3761 2.43e-137 394.0 COG0715@1|root,COG0715@2|Bacteria,1TRT8@1239|Firmicutes,4HCK6@91061|Bacilli,1ZB5K@1386|Bacillus 91061|Bacilli P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components ssuA - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1_2 k141_14961_2 1453501.JELR01000002_gene139 5.32e-140 402.0 COG0797@1|root,COG0797@2|Bacteria,1MZ8S@1224|Proteobacteria,1RMCG@1236|Gammaproteobacteria,466W8@72275|Alteromonadaceae 1236|Gammaproteobacteria M Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides rlpA GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - ko:K03642 - - - - ko00000 - - - DPBB_1,SPOR k141_14961_5 1453501.JELR01000002_gene142 0.0 1049.0 COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,1RN9H@1236|Gammaproteobacteria,464KX@72275|Alteromonadaceae 1236|Gammaproteobacteria M Catalyzes cross-linking of the peptidoglycan cell wall mrdA GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0045229,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 3.4.16.4 ko:K05515 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - iEcE24377_1341.EcE24377A_0661,iPC815.YPO2604 PBP_dimer,Transpeptidase k141_14961_7 1453501.JELR01000002_gene144 5.35e-64 196.0 COG0799@1|root,COG0799@2|Bacteria,1MZEF@1224|Proteobacteria,1S8W3@1236|Gammaproteobacteria,467TU@72275|Alteromonadaceae 1236|Gammaproteobacteria J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation rsfS GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113 - ko:K09710 - - - - ko00000,ko03009 - - - RsfS k141_14961_8 1279017.AQYJ01000024_gene916 8.98e-102 302.0 COG1057@1|root,COG1057@2|Bacteria,1RD0J@1224|Proteobacteria,1RP00@1236|Gammaproteobacteria,46745@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) nadD GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034355,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043094,GO:0043173,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18,3.5.4.4 ko:K00969,ko:K01488 ko00230,ko00760,ko01100,ko05340,map00230,map00760,map01100,map05340 M00115 R00137,R01560,R02556,R03005 RC00002,RC00477 ko00000,ko00001,ko00002,ko01000 - - iECUMN_1333.ECUMN_0733,iJN746.PP_4810,iPC815.YPO2607,iSbBS512_1146.SbBS512_E0612 CTP_transf_like k141_14961_9 1042377.AFPJ01000030_gene459 6.15e-233 650.0 COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,1RMAY@1236|Gammaproteobacteria,464S8@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate proA GO:0003674,GO:0003824,GO:0004350,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0055114,GO:0055129,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 M00015 R03313 RC00684 ko00000,ko00001,ko00002,ko01000 - - iB21_1397.B21_00243,iECBD_1354.ECBD_3376,iECB_1328.ECB_00240,iECD_1391.ECD_00240,iYL1228.KPN_00280 Aldedh k141_14961_10 1042377.AFPJ01000030_gene461 1.46e-91 272.0 COG2802@1|root,COG2802@2|Bacteria,1NV9N@1224|Proteobacteria,1T15C@1236|Gammaproteobacteria,46D1P@72275|Alteromonadaceae 1236|Gammaproteobacteria S ATP-dependent protease La (LON) substrate-binding domain - - - ko:K07157 - - - - ko00000 - - - LON_substr_bdg k141_14961_11 1453501.JELR01000002_gene149 5.58e-154 439.0 COG2321@1|root,COG2321@2|Bacteria,1MU4U@1224|Proteobacteria,1RMF8@1236|Gammaproteobacteria,466BZ@72275|Alteromonadaceae 1236|Gammaproteobacteria S Putative neutral zinc metallopeptidase - - - ko:K07054 - - - - ko00000 - - - Zn_peptidase k141_14961_13 1042377.AFPJ01000036_gene1134 1.54e-260 738.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MV8W@1224|Proteobacteria,1RMQA@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Outer membrane receptor proteins mostly Fe transport - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_1860_1 240302.BN982_00173 3.49e-22 88.2 2C0U7@1|root,32UM1@2|Bacteria,1VCIY@1239|Firmicutes,4HKGX@91061|Bacilli 91061|Bacilli S SPP1 phage holin - - - - - - - - - - - - Holin_SPP1 k141_23531_1 218284.CCDN010000002_gene2896 1.17e-57 181.0 2B4RH@1|root,31XHV@2|Bacteria,1V7MG@1239|Firmicutes,4HJAR@91061|Bacilli,1ZHAG@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - DUF2269 k141_34076_1 1453501.JELR01000001_gene2287 4.77e-94 297.0 COG0427@1|root,COG0427@2|Bacteria,1PJY0@1224|Proteobacteria,1RPS6@1236|Gammaproteobacteria,46523@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG0427 Acetyl-CoA hydrolase - - - - - - - - - - - - AcetylCoA_hyd_C k141_3068_1 1198452.Jab_2c18320 4.8e-41 143.0 2BIYM@1|root,32D6Z@2|Bacteria,1NDA6@1224|Proteobacteria,2W365@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k141_25866_1 1042377.AFPJ01000034_gene2358 7.16e-152 432.0 COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,1RM7U@1236|Gammaproteobacteria,463Z3@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA rsmI GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.198 ko:K07056 - - - - ko00000,ko01000,ko03009 - - - TP_methylase k141_25866_2 1453501.JELR01000001_gene3057 2.6e-313 870.0 COG3107@1|root,COG3107@2|Bacteria,1MUHR@1224|Proteobacteria,1RXX4@1236|Gammaproteobacteria,465I7@72275|Alteromonadaceae 1236|Gammaproteobacteria M (Lipo)protein lpoA GO:0000270,GO:0003674,GO:0005575,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009279,GO:0009987,GO:0016020,GO:0019867,GO:0030203,GO:0030234,GO:0030312,GO:0030313,GO:0031241,GO:0031975,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044425,GO:0044462,GO:0044464,GO:0050790,GO:0065007,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0098552,GO:0098772,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 - ko:K07121 - - - - ko00000 - - - LppC k141_25866_3 42565.FP66_00190 5.95e-22 91.3 COG0792@1|root,COG0792@2|Bacteria,1N6VN@1224|Proteobacteria,1SC8A@1236|Gammaproteobacteria,1XM4S@135619|Oceanospirillales 135619|Oceanospirillales L Belongs to the UPF0102 family - - - ko:K07460 - - - - ko00000 - - - UPF0102 k141_25866_4 1279017.AQYJ01000024_gene1073 9.28e-107 310.0 COG0279@1|root,COG0279@2|Bacteria,1NJ8X@1224|Proteobacteria,1RS1Y@1236|Gammaproteobacteria,466WU@72275|Alteromonadaceae 1236|Gammaproteobacteria G Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate gmhA - 5.3.1.28 ko:K03271,ko:K12961 ko00540,ko01100,map00540,map01100 M00064 R05645,R09768,R09769 RC00434 ko00000,ko00001,ko00002,ko01000,ko01005,ko03036 - - - SIS_2 k141_35353_1 1279017.AQYJ01000022_gene2683 6.62e-244 699.0 COG2304@1|root,COG2304@2|Bacteria,1MW8K@1224|Proteobacteria,1RNU3@1236|Gammaproteobacteria,46676@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein containing a von Willebrand factor type A (vWA) domain - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - VIT,VWA_3 k141_20907_1 626887.J057_05826 3.5e-52 177.0 COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,1MUDN@1224|Proteobacteria,1RMMG@1236|Gammaproteobacteria,465X6@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0491 Zn-dependent hydrolases, including glyoxylases - - 3.1.2.6 ko:K01069 ko00620,map00620 - R01736 RC00004,RC00137 ko00000,ko00001,ko01000 - - - Lactamase_B,Rhodanese k141_20907_2 1453501.JELR01000001_gene2591 4.2e-135 414.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,464AK@72275|Alteromonadaceae 1236|Gammaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran k141_6809_1 218284.CCDN010000006_gene3666 1.4e-93 284.0 COG0265@1|root,COG0265@2|Bacteria,1TSBA@1239|Firmicutes,4HA05@91061|Bacilli,1ZAQG@1386|Bacillus 91061|Bacilli O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain minJ - - - - - - - - - - - PDZ_2 k141_895_1 608538.HTH_0154 2.62e-24 97.8 COG1622@1|root,COG1622@2|Bacteria 2|Bacteria C oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor - - 1.9.3.1 ko:K02275 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.4,3.D.4.6 - - COX2 k141_11631_1 218284.CCDN010000002_gene2009 3.11e-106 335.0 COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,4HABE@91061|Bacilli,1ZPZA@1386|Bacillus 91061|Bacilli EF Carbamoyl-phosphate synthetase ammonia chain carB GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS k141_4630_1 1279017.AQYJ01000020_gene1277 1.34e-62 209.0 COG1566@1|root,COG1566@2|Bacteria,1RJ3I@1224|Proteobacteria,1S7BS@1236|Gammaproteobacteria,46ACD@72275|Alteromonadaceae 1236|Gammaproteobacteria V Protein of unknown function (DUF3667) - - - - - - - - - - - - DUF3667 k141_37859_1 218284.CCDN010000002_gene2851 6.59e-153 442.0 COG1649@1|root,COG1649@2|Bacteria,1TRTG@1239|Firmicutes,4HD0M@91061|Bacilli,1ZC0H@1386|Bacillus 91061|Bacilli T Glycosyl hydrolase-like 10 yngK - - - - - - - - - - - Big_2,Cu_amine_oxidN1,GHL10 k141_10668_2 935837.JAEK01000002_gene1982 5.37e-81 244.0 COG3402@1|root,COG3402@2|Bacteria,1V53A@1239|Firmicutes,4HHWE@91061|Bacilli,1ZRW6@1386|Bacillus 91061|Bacilli S Bacterial PH domain - - - ko:K09167 - - - - ko00000 - - - bPH_2 k141_28278_1 1116375.VEJY3_23326 3.26e-76 234.0 COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,1RPV9@1236|Gammaproteobacteria,1Y2NT@135623|Vibrionales 135623|Vibrionales P Binding-protein-dependent transport system inner membrane component - - - ko:K02038 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 k141_28278_2 223926.28809862 6.81e-134 385.0 COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,1RQXJ@1236|Gammaproteobacteria,1XSNI@135623|Vibrionales 135623|Vibrionales P probably responsible for the translocation of the substrate across the membrane pstC - - ko:K02037 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 k141_21234_1 1453501.JELR01000002_gene914 1e-94 283.0 COG0631@1|root,COG0631@2|Bacteria,1R7UF@1224|Proteobacteria,1RQUV@1236|Gammaproteobacteria,46CJT@72275|Alteromonadaceae 1236|Gammaproteobacteria T Protein phosphatase 2C - - 3.1.3.16 ko:K20074 - - - - ko00000,ko01000,ko01009 - - - PP2C_2 k141_21234_2 1279017.AQYJ01000027_gene1556 4.55e-109 318.0 COG1943@1|root,COG1943@2|Bacteria,1P19I@1224|Proteobacteria,1RQYI@1236|Gammaproteobacteria,46869@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG1943 Transposase and inactivated derivatives - - - ko:K07491 - - - - ko00000 - - - Y1_Tnp k141_30556_2 1122927.KB895413_gene1574 9.57e-47 154.0 2CJSB@1|root,340HJ@2|Bacteria,1VY1Q@1239|Firmicutes,4HX4I@91061|Bacilli,26YUP@186822|Paenibacillaceae 91061|Bacilli - - - - - - - - - - - - - - - k141_36560_1 223926.28809777 2.7e-130 381.0 2B0YY@1|root,31TC3@2|Bacteria,1QJFI@1224|Proteobacteria,1THEY@1236|Gammaproteobacteria,1XV4K@135623|Vibrionales 135623|Vibrionales S O-Antigen ligase - - - - - - - - - - - - Wzy_C k141_3450_1 66874.JOFS01000028_gene1768 4.17e-18 85.5 COG0609@1|root,COG0609@2|Bacteria,2GK8Z@201174|Actinobacteria 201174|Actinobacteria P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily - - - ko:K02015 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - FecCD k141_37860_1 1177154.Y5S_01706 6.81e-34 136.0 COG1361@1|root,COG1361@2|Bacteria,1QVSF@1224|Proteobacteria 1224|Proteobacteria M domain protein - - - - - - - - - - - - CARDB,DUF11,OmpA_membrane k141_28280_1 1385511.N783_16885 1.01e-45 155.0 COG0346@1|root,COG0346@2|Bacteria,1V9DI@1239|Firmicutes,4HJGV@91061|Bacilli,2YBHT@289201|Pontibacillus 91061|Bacilli E lactoylglutathione lyase activity - - - - - - - - - - - - - k141_31717_1 42565.FP66_07605 7.83e-137 397.0 COG4536@1|root,COG4536@2|Bacteria,1NZ99@1224|Proteobacteria,1RNCE@1236|Gammaproteobacteria,1XH4G@135619|Oceanospirillales 135619|Oceanospirillales P Mg2 and Co2 transporter CorB - - - - - - - - - - - - CBS,CorC_HlyC,DUF21 k141_31717_2 42565.FP66_07600 8.8e-29 109.0 COG4137@1|root,COG4137@2|Bacteria,1R3YD@1224|Proteobacteria,1RPUQ@1236|Gammaproteobacteria,1XI5V@135619|Oceanospirillales 135619|Oceanospirillales S cytochrome C - - - - - - - - - - - - Cytochrom_C_asm k141_36561_1 1196031.ALEG01000049_gene352 1.61e-15 69.3 2DIQB@1|root,303WI@2|Bacteria,1TVCP@1239|Firmicutes,4IJW2@91061|Bacilli,1ZK1N@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_16567_1 223926.28806009 0.0 1709.0 COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,1RNZ2@1236|Gammaproteobacteria,1XSSB@135623|Vibrionales 135623|Vibrionales L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topA GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.2 ko:K03168 - - - - ko00000,ko01000,ko03032,ko03400 - - - Topo_Zn_Ribbon,Topoisom_bac,Toprim,zf-C4_Topoisom k141_16567_2 223926.28806008 4.52e-48 154.0 2CK10@1|root,32SBA@2|Bacteria,1N8PV@1224|Proteobacteria,1S938@1236|Gammaproteobacteria,1XYF4@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF2498) STY1335 - - - - - - - - - - - DUF2498 k141_16567_3 1116375.VEJY3_04740 8.45e-300 818.0 COG0128@1|root,COG0128@2|Bacteria,1MWMK@1224|Proteobacteria,1RQ8U@1236|Gammaproteobacteria,1XSTG@135623|Vibrionales 135623|Vibrionales E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate aroA GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03460 RC00350 ko00000,ko00001,ko00002,ko01000 - - - EPSP_synthase k141_16567_4 1116375.VEJY3_04730 2e-150 425.0 COG2360@1|root,COG2360@2|Bacteria,1R9W8@1224|Proteobacteria,1S1ZB@1236|Gammaproteobacteria,1XU2W@135623|Vibrionales 135623|Vibrionales O Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine aat GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.3.2.6 ko:K00684 - - R03813,R11443,R11444 RC00055,RC00064 ko00000,ko01000 - - - Leu_Phe_trans k141_16567_5 1116375.VEJY3_04725 7.05e-154 433.0 COG2935@1|root,COG2935@2|Bacteria,1MW62@1224|Proteobacteria,1RYD7@1236|Gammaproteobacteria,1XSUB@135623|Vibrionales 135623|Vibrionales O May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate ate GO:0003674,GO:0003824,GO:0004057,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016598,GO:0016740,GO:0016746,GO:0016755,GO:0019538,GO:0019941,GO:0030163,GO:0036211,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 2.3.2.29 ko:K21420 - - R11547,R11548 RC00064 ko00000,ko01000 - - - ATE_C,ATE_N k141_16567_7 1116375.VEJY3_04715 3.61e-218 620.0 COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,1RMH3@1236|Gammaproteobacteria,1XSKE@135623|Vibrionales 135623|Vibrionales O Belongs to the ClpA ClpB family clpA - - ko:K03694 - - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N k141_10670_1 218284.CCDN010000001_gene585 5.96e-120 350.0 COG5401@1|root,COG5401@2|Bacteria,1TPQD@1239|Firmicutes,4HB1S@91061|Bacilli,1ZBZJ@1386|Bacillus 91061|Bacilli S COG5401 Spore germination protein gerM - - ko:K06298 - - - - ko00000 - - - Germane k141_33168_2 218284.CCDN010000003_gene3014 3.32e-96 283.0 COG0801@1|root,COG0801@2|Bacteria,1V6PR@1239|Firmicutes,4HIMG@91061|Bacilli,1ZGBC@1386|Bacillus 91061|Bacilli H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase folK - 2.7.6.3 ko:K00950 ko00790,ko01100,map00790,map01100 M00126,M00841 R03503 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - HPPK k141_31718_1 1453501.JELR01000001_gene2840 2.45e-57 189.0 COG0585@1|root,COG0585@2|Bacteria,1MXHD@1224|Proteobacteria,1RPRF@1236|Gammaproteobacteria,465C2@72275|Alteromonadaceae 1236|Gammaproteobacteria J Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs truD GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 ko:K06176 - - - - ko00000,ko01000,ko03016 - - - TruD k141_2231_1 56780.SYN_01162 2.37e-78 241.0 COG0428@1|root,COG0428@2|Bacteria,1R40E@1224|Proteobacteria,43B49@68525|delta/epsilon subdivisions,2X6I2@28221|Deltaproteobacteria 28221|Deltaproteobacteria P ZIP Zinc transporter - - - ko:K16267 - - - - ko00000,ko02000 2.A.5.4.11 - - Zip k141_2231_2 247633.GP2143_13661 1.2e-08 55.8 COG0428@1|root,COG0428@2|Bacteria,1R40E@1224|Proteobacteria,1RRYS@1236|Gammaproteobacteria,1J6RV@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P ZIP Zinc transporter - - - ko:K16267 - - - - ko00000,ko02000 2.A.5.4.11 - - Zip k141_37861_2 218284.CCDN010000001_gene1891 4.73e-134 387.0 COG0195@1|root,COG0195@2|Bacteria,1TPB3@1239|Firmicutes,4HA7F@91061|Bacilli,1ZDAH@1386|Bacillus 91061|Bacilli K Participates in both transcription termination and antitermination nusA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K02600 - - - - ko00000,ko03009,ko03021 - - - KH_5,NusA_N,S1 k141_36563_1 545693.BMQ_1073 1.12e-24 102.0 COG0160@1|root,COG0160@2|Bacteria,1VS6F@1239|Firmicutes,4H9M7@91061|Bacilli,1ZAZ9@1386|Bacillus 91061|Bacilli E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - 2.6.1.19,2.6.1.22 ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 M00027 R00908,R01648,R04188 RC00006,RC00062,RC00160 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 k141_34431_1 316275.VSAL_I1253 5.5e-108 333.0 COG2936@1|root,COG2936@2|Bacteria,1MVA8@1224|Proteobacteria,1TBNS@1236|Gammaproteobacteria,1Y16K@135623|Vibrionales 135623|Vibrionales S X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain - - - ko:K06978 - - - - ko00000 - - - PepX_C,Peptidase_S15 k141_34431_2 316275.VSAL_I1254 4.34e-299 823.0 COG1292@1|root,COG1292@2|Bacteria,1QSN7@1224|Proteobacteria,1RYYU@1236|Gammaproteobacteria,1XWBY@135623|Vibrionales 135623|Vibrionales M Belongs to the BCCT transporter (TC 2.A.15) family - - - - - - - - - - - - BCCT k141_34431_3 1116375.VEJY3_23966 1.32e-183 512.0 COG2207@1|root,COG2207@2|Bacteria,1R4RI@1224|Proteobacteria,1RZFI@1236|Gammaproteobacteria,1XX1W@135623|Vibrionales 135623|Vibrionales K helix_turn_helix, arabinose operon control protein - - - - - - - - - - - - HTH_18 k141_34431_4 400668.Mmwyl1_3168 1.63e-09 58.2 COG2423@1|root,COG2423@2|Bacteria,1PPG3@1224|Proteobacteria,1RYPX@1236|Gammaproteobacteria,1XNRK@135619|Oceanospirillales 135619|Oceanospirillales E PFAM Ornithine cyclodeaminase mu-crystallin - - 4.3.1.12 ko:K01750 ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230 - R00671 RC00354 ko00000,ko00001,ko01000 - - - OCD_Mu_crystall k141_34431_5 1116375.VEJY3_23961 3.2e-247 680.0 COG2423@1|root,COG2423@2|Bacteria,1PPG3@1224|Proteobacteria,1RYPX@1236|Gammaproteobacteria,1XVP6@135623|Vibrionales 135623|Vibrionales E Ornithine cyclodeaminase/mu-crystallin family - - - - - - - - - - - - OCD_Mu_crystall k141_34431_6 1116375.VEJY3_23956 1.17e-72 220.0 COG0251@1|root,COG0251@2|Bacteria,1RH61@1224|Proteobacteria,1S4QT@1236|Gammaproteobacteria,1XXJ5@135623|Vibrionales 135623|Vibrionales J Endoribonuclease L-PSP - - - - - - - - - - - - Ribonuc_L-PSP k141_34431_7 1116375.VEJY3_23951 2.99e-201 564.0 COG0665@1|root,COG0665@2|Bacteria,1MU7M@1224|Proteobacteria,1RP7W@1236|Gammaproteobacteria,1XWHB@135623|Vibrionales 135623|Vibrionales E FAD dependent oxidoreductase - - - - - - - - - - - - DAO k141_16569_1 1453501.JELR01000002_gene486 9.87e-50 174.0 COG1629@1|root,COG4771@2|Bacteria,1MUWN@1224|Proteobacteria,1S005@1236|Gammaproteobacteria,46A62@72275|Alteromonadaceae 1236|Gammaproteobacteria P Outer membrane protein beta-barrel family - - - - - - - - - - - - Plug,TonB_dep_Rec k141_16569_2 1453501.JELR01000002_gene485 6.02e-20 88.2 COG2365@1|root,COG2365@2|Bacteria,1R4XF@1224|Proteobacteria,1RMPM@1236|Gammaproteobacteria,466PW@72275|Alteromonadaceae 1236|Gammaproteobacteria T Tyrosine phosphatase family - - - - - - - - - - - - Y_phosphatase3 k141_31719_1 1116375.VEJY3_24281 5.74e-55 184.0 COG0591@1|root,COG0591@2|Bacteria,1MUBI@1224|Proteobacteria,1RMXU@1236|Gammaproteobacteria,1XSU8@135623|Vibrionales 135623|Vibrionales E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family putP - - ko:K11928 - - - - ko00000,ko02000 2.A.21.2 - - SSF k141_21239_1 218284.CCDN010000002_gene2036 7.33e-105 310.0 COG2049@1|root,COG2049@2|Bacteria,1TTBZ@1239|Firmicutes,4HHJJ@91061|Bacilli,1ZDVS@1386|Bacillus 91061|Bacilli E Allophanate hydrolase subunit 1 kipI - - ko:K06351 - - - - ko00000 - - - CT_C_D k141_37863_2 1294265.JCM21738_358 3.45e-57 177.0 COG1550@1|root,COG1550@2|Bacteria,1VEHY@1239|Firmicutes,4HNXC@91061|Bacilli,1ZI43@1386|Bacillus 91061|Bacilli S protein conserved in bacteria ylxP - - ko:K09764 - - - - ko00000 - - - DUF503 k141_16570_2 218284.CCDN010000001_gene1481 2.47e-09 56.2 COG0503@1|root,COG0503@2|Bacteria,1V1DU@1239|Firmicutes,4HFNW@91061|Bacilli,1ZFTS@1386|Bacillus 91061|Bacilli F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis xpt - 2.4.2.22 ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 - R01229,R02142 RC00063,RC00122 ko00000,ko00001,ko01000 - - iYO844.BSU22070 Pribosyltran k141_34432_1 333138.LQ50_08870 8.07e-19 82.8 COG0778@1|root,COG0778@2|Bacteria,1V1PI@1239|Firmicutes,4HB7V@91061|Bacilli,1ZBI6@1386|Bacillus 91061|Bacilli C nitroreductase frp - - - - - - - - - - iYO844.BSU07830 Nitroreductase k141_34432_2 218284.CCDN010000002_gene2828 1.07e-47 166.0 COG5000@1|root,COG5000@2|Bacteria,1UIX3@1239|Firmicutes,4ISV9@91061|Bacilli,1ZS6Y@1386|Bacillus 91061|Bacilli T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA k141_31720_1 1453501.JELR01000002_gene1359 1.57e-51 178.0 COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,1RPFM@1236|Gammaproteobacteria,4673P@72275|Alteromonadaceae 1236|Gammaproteobacteria M protein involved in outer membrane biogenesis asmA - - ko:K07289 - - - - ko00000 - - - AsmA k141_4637_1 265729.GS18_0206755 6.82e-103 303.0 COG1028@1|root,COG1028@2|Bacteria,1TP3G@1239|Firmicutes,4HACT@91061|Bacilli,1ZDEW@1386|Bacillus 91061|Bacilli IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate - - 1.1.1.30 ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 M00088 R01361 RC00117 ko00000,ko00001,ko00002,ko01000 - - - adh_short_C2 k141_17739_1 1116375.VEJY3_00960 0.0 969.0 COG4775@1|root,COG4775@2|Bacteria,1MX3H@1224|Proteobacteria,1RQKV@1236|Gammaproteobacteria,1XSM5@135623|Vibrionales 135623|Vibrionales M Exopolysaccharide biosynthesis protein YbjH wbfB - - - - - - - - - - - YjbH k141_17739_2 1116375.VEJY3_00965 1.65e-110 325.0 2AVWN@1|root,31MQJ@2|Bacteria,1QJHN@1224|Proteobacteria,1THHJ@1236|Gammaproteobacteria,1XVW1@135623|Vibrionales 135623|Vibrionales S Capsule biosynthesis GfcC - - - - - - - - - - - - Caps_synth_GfcC k141_17739_3 1280001.BAOA01000021_gene713 9.61e-118 341.0 28M8B@1|root,2ZAMG@2|Bacteria,1N1VT@1224|Proteobacteria,1RMP6@1236|Gammaproteobacteria,1XXFZ@135623|Vibrionales 135623|Vibrionales S Group 4 capsule polysaccharide lipoprotein gfcB, YjbF VP0217 - - - - - - - - - - - YjbF k141_21240_1 1042377.AFPJ01000053_gene1509 9.05e-14 73.2 COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria,4658C@72275|Alteromonadaceae 1236|Gammaproteobacteria V COG1132 ABC-type multidrug transport system, ATPase and permease components draA - - ko:K06147,ko:K11085 ko02010,map02010 - - - ko00000,ko00001,ko01000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran k141_36566_2 218284.CCDN010000001_gene1401 2.36e-17 80.5 COG0006@1|root,COG0006@2|Bacteria,1V22K@1239|Firmicutes,4HTV2@91061|Bacilli,1ZNEY@1386|Bacillus 91061|Bacilli E Metallopeptidase family M24 - - - - - - - - - - - - - k141_2235_1 218284.CCDN010000001_gene1623 5.5e-37 127.0 COG1670@1|root,COG1670@2|Bacteria,1U9TB@1239|Firmicutes,4IK0N@91061|Bacilli,1ZN64@1386|Bacillus 91061|Bacilli J FR47-like protein - - - - - - - - - - - - Acetyltransf_1 k141_30558_1 1042377.AFPJ01000043_gene883 6.56e-184 525.0 COG0477@1|root,COG2814@2|Bacteria,1QKNX@1224|Proteobacteria,1RXRI@1236|Gammaproteobacteria,46723@72275|Alteromonadaceae 1236|Gammaproteobacteria EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 k141_30558_2 1042377.AFPJ01000043_gene882 7.35e-147 431.0 COG1167@1|root,COG1167@2|Bacteria,1MVGT@1224|Proteobacteria,1RPFK@1236|Gammaproteobacteria,465V7@72275|Alteromonadaceae 1236|Gammaproteobacteria K helix_turn_helix gluconate operon transcriptional repressor - - - ko:K00375,ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 - R01939 RC00006 ko00000,ko00001,ko01000,ko03000 - - - Aminotran_1_2,GntR k141_16572_1 218284.CCDN010000005_gene3184 3.04e-126 370.0 COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,4H9WQ@91061|Bacilli,1ZAR7@1386|Bacillus 91061|Bacilli E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase yhaA - - ko:K01436 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 k141_10672_3 1340434.AXVA01000002_gene1295 3.39e-16 83.6 COG1674@1|root,COG1674@2|Bacteria,1TWB0@1239|Firmicutes,4HCGJ@91061|Bacilli,1ZD0W@1386|Bacillus 91061|Bacilli D FtsK/SpoIIIE family - - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_SpoIIIE k141_21242_1 545693.BMQ_2629 1.91e-12 65.1 29J4G@1|root,3061X@2|Bacteria,1TZ1P@1239|Firmicutes,4I88A@91061|Bacilli,1ZJRY@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_21242_2 1007103.AFHW01000087_gene6333 4.58e-18 84.7 COG1376@1|root,COG1376@2|Bacteria,1U2DJ@1239|Firmicutes,4IBZC@91061|Bacilli,271R4@186822|Paenibacillaceae 91061|Bacilli S L,D-transpeptidase catalytic domain - - - - - - - - - - - - YkuD k141_3451_1 1453501.JELR01000001_gene3198 1.83e-286 809.0 COG3240@1|root,COG3240@2|Bacteria,1RCCU@1224|Proteobacteria,1S2GX@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Phospholipase lecithinase hemolysin estA GO:0003674,GO:0003824,GO:0016289,GO:0016290,GO:0016787,GO:0016788,GO:0016790,GO:0047617,GO:0052689 - ko:K12686 - - - - ko00000,ko02000,ko02044 1.B.12.8 - - Autotransporter,Lipase_GDSL k141_31721_1 218284.CCDN010000002_gene2118 3.42e-222 625.0 COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,4H9VR@91061|Bacilli,1ZB1D@1386|Bacillus 91061|Bacilli E Acetolactate synthase ilvB - 2.2.1.6 ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 M00019,M00570,M00582 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N k141_28281_1 314282.PCNPT3_05325 7.69e-43 157.0 COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria,1N6EM@1224|Proteobacteria,1RWSY@1236|Gammaproteobacteria,2QI03@267894|Psychromonadaceae 1224|Proteobacteria M COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins ompA GO:0000746,GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006950,GO:0006974,GO:0008150,GO:0009279,GO:0009597,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0015267,GO:0015288,GO:0016020,GO:0016021,GO:0016032,GO:0019058,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030260,GO:0030312,GO:0030313,GO:0031224,GO:0031975,GO:0032991,GO:0033554,GO:0034220,GO:0042802,GO:0043207,GO:0044403,GO:0044409,GO:0044419,GO:0044425,GO:0044462,GO:0044464,GO:0044764,GO:0046718,GO:0046930,GO:0050896,GO:0051179,GO:0051234,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051806,GO:0051828,GO:0055085,GO:0071944,GO:0098796 - ko:K03286 - - - - ko00000,ko02000 1.B.6 - iECIAI1_1343.ECIAI1_0998,iECNA114_1301.ECNA114_1035,iECSF_1327.ECSF_0871,iUTI89_1310.UTI89_C1022 OMP_b-brl,OmpA,OmpA_membrane,SmpA_OmlA k141_28281_2 1116375.VEJY3_16111 1.89e-86 255.0 COG0346@1|root,COG0346@2|Bacteria,1RHD4@1224|Proteobacteria,1SB56@1236|Gammaproteobacteria,1XXBI@135623|Vibrionales 135623|Vibrionales E COG0346 Lactoylglutathione lyase and related lyases - - - - - - - - - - - - Glyoxalase k141_28281_3 1116375.VEJY3_16106 1.58e-89 266.0 COG2110@1|root,COG2110@2|Bacteria,1RCWP@1224|Proteobacteria,1S3WJ@1236|Gammaproteobacteria,1XX2U@135623|Vibrionales 135623|Vibrionales S Appr-1'-p processing enzyme - - - - - - - - - - - - Macro k141_28281_4 1219076.N646_3539 1.78e-49 157.0 COG4568@1|root,COG4568@2|Bacteria,1N82G@1224|Proteobacteria,1SCJ9@1236|Gammaproteobacteria,1XZ1U@135623|Vibrionales 135623|Vibrionales K COG4568 Transcriptional antiterminator - - - ko:K19000 - - - - ko00000,ko03021 - - - ROF k141_3492_1 997296.PB1_05552 2.05e-170 494.0 COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,4HA1D@91061|Bacilli,1ZATN@1386|Bacillus 91061|Bacilli L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA ligA GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - - BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5 k141_2308_1 218284.CCDN010000008_gene4208 6.62e-108 311.0 28NR0@1|root,2ZBQD@2|Bacteria,1V1Z5@1239|Firmicutes,4HGAG@91061|Bacilli,1ZE4G@1386|Bacillus 91061|Bacilli S Nucleoside 2-deoxyribosyltransferase YtoQ ytoQ - - - - - - - - - - - Nuc_deoxyri_tr3 k141_28360_1 1033734.CAET01000044_gene560 8.65e-45 161.0 COG4585@1|root,COG4585@2|Bacteria,1V3N2@1239|Firmicutes,4HHKF@91061|Bacilli,1ZDEM@1386|Bacillus 91061|Bacilli T Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - - - - - - - - - - GAF,HATPase_c,HisKA_3 k141_28360_2 91464.S7335_313 1.82e-27 107.0 COG2197@1|root,COG2197@2|Bacteria,1G23F@1117|Cyanobacteria,1H3XM@1129|Synechococcus 1117|Cyanobacteria K helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE,Response_reg k141_16615_1 318161.Sden_2973 2.51e-47 163.0 COG2356@1|root,COG2356@2|Bacteria,1MXQM@1224|Proteobacteria,1RPX9@1236|Gammaproteobacteria,2Q9RG@267890|Shewanellaceae 1236|Gammaproteobacteria L PFAM Endonuclease I endA GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005623,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0016888,GO:0016893,GO:0019439,GO:0034641,GO:0034655,GO:0042597,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 3.1.21.1 ko:K01150 - - - - ko00000,ko01000 - - - Endonuclease_1 k141_16615_2 234831.PSM_B0621 1.35e-95 300.0 COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,1RMT1@1236|Gammaproteobacteria,2PZGT@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria L COG0389 Nucleotidyltransferase DNA polymerase involved in DNA repair umuC - - ko:K03502 - - - - ko00000,ko03400 - - - DUF4113,IMS,IMS_C,IMS_HHH k141_16615_3 1208583.COMX_06235 8.22e-15 76.3 COG1974@1|root,COG1974@2|Bacteria,1MZFA@1224|Proteobacteria,2UCXW@28211|Alphaproteobacteria,2JUZ3@204441|Rhodospirillales 204441|Rhodospirillales KT COG1974 SOS-response transcriptional repressors (RecA-mediated autopeptidases) - - - ko:K03503 - - - - ko00000,ko01000,ko01002,ko03400 - - - Peptidase_S24 k141_16615_4 1500259.JQLD01000012_gene5335 3.57e-22 91.7 COG1226@1|root,32YV7@2|Bacteria,1N7MV@1224|Proteobacteria,2UMMN@28211|Alphaproteobacteria,4BMUM@82115|Rhizobiaceae 28211|Alphaproteobacteria P Ion channel - - - - - - - - - - - - Ion_trans_2 k141_16615_5 1279017.AQYJ01000029_gene3816 1.75e-193 554.0 COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,1RN5K@1236|Gammaproteobacteria,466GP@72275|Alteromonadaceae 1236|Gammaproteobacteria MU Outer membrane efflux protein lprN - - - - - - - - - - - OEP k141_16615_6 596151.DesfrDRAFT_2501 1.18e-90 283.0 COG1566@1|root,COG1566@2|Bacteria,1MWG0@1224|Proteobacteria,42NAT@68525|delta/epsilon subdivisions,2WPPB@28221|Deltaproteobacteria,2MBTW@213115|Desulfovibrionales 28221|Deltaproteobacteria V Biotin-lipoyl like - - - - - - - - - - - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 k141_16615_7 911045.PSE_3738 4.71e-13 64.7 29ZH6@1|root,30MGX@2|Bacteria,1Q4G5@1224|Proteobacteria,2UN38@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF1656) - - - - - - - - - - - - DUF1656 k141_28361_1 1453501.JELR01000002_gene55 3.97e-88 289.0 COG2911@1|root,COG2911@2|Bacteria,1MUVD@1224|Proteobacteria 1224|Proteobacteria M Protein conserved in bacteria tamB - - ko:K09800 - - - - ko00000,ko02000 - - - TamB k141_3493_1 866895.HBHAL_4221 9.68e-08 50.1 2DJ3D@1|root,304PD@2|Bacteria,1TWZI@1239|Firmicutes,4I5UG@91061|Bacilli,3NG6W@45667|Halobacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_3493_2 315730.BcerKBAB4_2975 1.19e-70 216.0 COG2318@1|root,COG2318@2|Bacteria,1V95A@1239|Firmicutes,4HJF3@91061|Bacilli,1ZGBP@1386|Bacillus 91061|Bacilli S DinB superfamily - - - - - - - - - - - - DinB_2 k141_4695_1 228405.HNE_2813 1.05e-49 182.0 COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,2TRUM@28211|Alphaproteobacteria,43ZJP@69657|Hyphomonadaceae 28211|Alphaproteobacteria E aminopeptidase - - - - - - - - - - - - ERAP1_C,Peptidase_M1 k141_4695_2 1443665.JACA01000049_gene5415 1.18e-99 320.0 COG1680@1|root,COG1680@2|Bacteria,4NEEP@976|Bacteroidetes,1I052@117743|Flavobacteriia,2YJC5@290174|Aquimarina 976|Bacteroidetes V Beta-lactamase - - - - - - - - - - - - Beta-lactamase k141_4695_3 1042377.AFPJ01000043_gene888 1.7e-95 294.0 COG2936@1|root,COG2936@2|Bacteria,1QU2I@1224|Proteobacteria,1S1VW@1236|Gammaproteobacteria,469YI@72275|Alteromonadaceae 1236|Gammaproteobacteria S X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain - - - - - - - - - - - - PepX_C,Peptidase_S15 k141_21318_1 1279017.AQYJ01000024_gene859 2.05e-96 281.0 COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,1S3Y7@1236|Gammaproteobacteria,4677T@72275|Alteromonadaceae 1236|Gammaproteobacteria S Required for maturation of 30S ribosomal subunits rimP GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - ko:K09748 - - - - ko00000,ko03009 - - - DUF150,DUF150_C k141_21318_3 1279017.AQYJ01000024_gene861 1.16e-35 142.0 COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,1RM9X@1236|Gammaproteobacteria,46433@72275|Alteromonadaceae 1236|Gammaproteobacteria J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019538,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034645,GO:0036094,GO:0043021,GO:0043024,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:0097216,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N,IF2_assoc k141_37936_1 1453501.JELR01000002_gene132 7.81e-232 677.0 COG0591@1|root,COG0784@1|root,COG4191@1|root,COG0591@2|Bacteria,COG0784@2|Bacteria,COG4191@2|Bacteria,1QTSW@1224|Proteobacteria,1T1G2@1236|Gammaproteobacteria,46D5M@72275|Alteromonadaceae 1236|Gammaproteobacteria T PAS fold - - - - - - - - - - - - HATPase_c,HisKA,PAS_4,PAS_7,Response_reg,SSF k141_3494_1 313595.P700755_001169 3.01e-36 130.0 COG4319@1|root,COG4319@2|Bacteria,4NYPP@976|Bacteroidetes 976|Bacteroidetes S Domain of unknown function (DUF4440) - - - - - - - - - - - - DUF4440 k141_30613_1 1279017.AQYJ01000027_gene1557 9.58e-97 292.0 COG0631@1|root,COG0631@2|Bacteria,1R7UF@1224|Proteobacteria,1RQUV@1236|Gammaproteobacteria,46CJT@72275|Alteromonadaceae 1236|Gammaproteobacteria T Protein phosphatase 2C - - 3.1.3.16 ko:K20074 - - - - ko00000,ko01000,ko01009 - - - PP2C_2 k141_30613_2 1453501.JELR01000001_gene3276 7.37e-81 243.0 COG0386@1|root,COG0386@2|Bacteria,1RD1R@1224|Proteobacteria,1S425@1236|Gammaproteobacteria,4671Y@72275|Alteromonadaceae 1236|Gammaproteobacteria O Belongs to the glutathione peroxidase family btuE - 1.11.1.9 ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 - R00274,R07034,R07035 RC00011,RC00982 ko00000,ko00001,ko01000 - - - GSHPx k141_30613_3 1279017.AQYJ01000022_gene2582 3.64e-63 198.0 COG1846@1|root,COG1846@2|Bacteria,1RH1F@1224|Proteobacteria,1S8WM@1236|Gammaproteobacteria,468SH@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG1846 Transcriptional regulators - - - - - - - - - - - - MarR k141_2309_1 672.VV93_v1c17500 1.12e-122 359.0 COG3203@1|root,COG3203@2|Bacteria,1Q1XX@1224|Proteobacteria,1RPIH@1236|Gammaproteobacteria,1XXTE@135623|Vibrionales 135623|Vibrionales M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - - - - - - - - - - - k141_2309_2 672.VV93_v1c17490 3.14e-176 510.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XX1J@135623|Vibrionales 135623|Vibrionales T Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal k141_30614_1 935836.JAEL01000105_gene2395 1.2e-138 417.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,4H9S7@91061|Bacilli,1ZB6Y@1386|Bacillus 91061|Bacilli L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A k141_21321_1 1294265.JCM21738_3151 1.88e-102 298.0 COG2190@1|root,COG2190@2|Bacteria,1VAEB@1239|Firmicutes,4HIPR@91061|Bacilli,1ZG91@1386|Bacillus 91061|Bacilli G COG2190 Phosphotransferase system IIA components crr - - ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 M00265,M00266,M00268,M00270,M00272,M00303,M00806 R02738,R02780,R04111,R04394,R05132,R08559 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.1 - - PTS_EIIA_1 k141_37937_1 218284.CCDN010000002_gene2391 3.2e-160 460.0 COG0477@1|root,COG2814@2|Bacteria,1V0D1@1239|Firmicutes,4HESH@91061|Bacilli,1ZR88@1386|Bacillus 91061|Bacilli EGP Transmembrane secretion effector - - - - - - - - - - - - MFS_1 k141_2310_1 1294265.JCM21738_3171 2.64e-50 166.0 COG1171@1|root,COG1171@2|Bacteria,1TP22@1239|Firmicutes,4H9NK@91061|Bacilli,1ZBM0@1386|Bacillus 91061|Bacilli E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA ilvA GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - - PALP,Thr_dehydrat_C k141_10797_1 218284.CCDN010000001_gene665 3.24e-133 399.0 COG0608@1|root,COG0608@2|Bacteria,1TPXE@1239|Firmicutes,4H9UP@91061|Bacilli,1ZBAT@1386|Bacillus 91061|Bacilli L Single-stranded-DNA-specific exonuclease RecJ recJ - - ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1,ssDNA-exonuc_C k141_3720_1 1123236.KB899380_gene2915 1.57e-10 60.8 COG0845@1|root,COG0845@2|Bacteria,1PZ6R@1224|Proteobacteria,1RRGC@1236|Gammaproteobacteria,465NS@72275|Alteromonadaceae 1236|Gammaproteobacteria M Biotin-lipoyl like - - - - - - - - - - - - Biotin_lipoyl_2,HlyD_3 k141_3720_2 1123236.KB899380_gene2916 2.71e-79 252.0 COG2274@1|root,COG2274@2|Bacteria,1MXTI@1224|Proteobacteria,1RQ97@1236|Gammaproteobacteria,464ZS@72275|Alteromonadaceae 1236|Gammaproteobacteria V ABC transporter, ATP-binding protein - - - ko:K02021 - - - - ko00000,ko02000 3.A.1.106,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21 - - ABC_membrane k141_2527_2 1453501.JELR01000002_gene1122 1.64e-130 372.0 COG0357@1|root,COG0357@2|Bacteria,1MY0K@1224|Proteobacteria,1RMRZ@1236|Gammaproteobacteria,466SB@72275|Alteromonadaceae 1236|Gammaproteobacteria J Specifically methylates the N7 position of guanine in position 527 of 16S rRNA rsmG GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 ko:K03501 - - - - ko00000,ko01000,ko03009,ko03036 - - - GidB k141_26313_1 218284.CCDN010000001_gene988 2.32e-100 323.0 COG1404@1|root,COG4412@1|root,COG1404@2|Bacteria,COG4412@2|Bacteria,1TPUY@1239|Firmicutes,4HBDE@91061|Bacilli,1ZDEQ@1386|Bacillus 91061|Bacilli O COG1404 Subtilisin-like serine proteases bpr GO:0005575,GO:0005576 - ko:K13276 - - - - ko00000,ko01000,ko01002,ko03110 - - - CarbopepD_reg_2,CarboxypepD_reg,Inhibitor_I9,Peptidase_M6,Peptidase_S8 k141_1254_1 1089550.ATTH01000001_gene2320 3.58e-05 49.3 COG1972@1|root,COG1972@2|Bacteria,4NEYN@976|Bacteroidetes,1FIW1@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes F Na+ dependent nucleoside transporter C-terminus nupC - - ko:K03317 - - - - ko00000 2.A.41 - - Gate,Nucleos_tra2_C,Nucleos_tra2_N k141_1254_2 1448389.BAVQ01000005_gene3057 2.95e-57 194.0 COG1816@1|root,COG1816@2|Bacteria,2GJ6I@201174|Actinobacteria 201174|Actinobacteria F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism add GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009119,GO:0009163,GO:0009164,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659 3.5.4.4 ko:K01488 ko00230,ko01100,ko05340,map00230,map01100,map05340 - R01560,R02556 RC00477 ko00000,ko00001,ko01000 - - iNJ661.Rv3313c A_deaminase k141_14418_2 218284.CCDN010000001_gene1037 2.08e-44 144.0 2E9B4@1|root,333IZ@2|Bacteria,1VHUQ@1239|Firmicutes,4HR2C@91061|Bacilli,1ZIY4@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF4227) - - - - - - - - - - - - DUF4227 k141_14418_3 218284.CCDN010000001_gene1038 6.84e-24 97.4 COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,4HAEX@91061|Bacilli,1ZDBF@1386|Bacillus 91061|Bacilli L recombinase XerD xerD - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase k141_186_1 218284.CCDN010000004_gene3126 1.37e-153 443.0 COG1288@1|root,COG1288@2|Bacteria,1TQJ0@1239|Firmicutes,4H9P7@91061|Bacilli,1ZBC6@1386|Bacillus 91061|Bacilli S Membrane ycgA - - - - - - - - - - - DcuC k141_6114_1 1294265.JCM21738_135 2.92e-82 249.0 28RMR@1|root,2ZE0H@2|Bacteria,1V1HS@1239|Firmicutes,4HFRG@91061|Bacilli,1ZANV@1386|Bacillus 91061|Bacilli S sporulation protein ypjB - - - - - - - - - - - Spore_YpjB k141_29852_2 218284.CCDN010000006_gene3543 1.94e-57 187.0 COG0583@1|root,COG0583@2|Bacteria,1TRYW@1239|Firmicutes,4H9T5@91061|Bacilli,1ZC6S@1386|Bacillus 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_28727_1 218284.CCDN010000001_gene90 5.49e-72 235.0 COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,4H9VQ@91061|Bacilli,1ZASE@1386|Bacillus 91061|Bacilli M Penicillin-binding Protein pbpX GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - - PASTA,PBP_dimer,Transpeptidase k141_9641_1 1218173.BALCAV_0209890 6.58e-15 74.7 COG1823@1|root,COG1823@2|Bacteria,1UPUK@1239|Firmicutes,4HAJY@91061|Bacilli,1ZB7C@1386|Bacillus 91061|Bacilli U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family tcyP - - ko:K06956 - - - - ko00000 - - - SDF k141_9641_2 391295.SSU05_0735 7.91e-08 55.1 COG0352@1|root,COG0352@2|Bacteria,1V3ZR@1239|Firmicutes,4HH1E@91061|Bacilli,1WTXG@1307|Streptococcus suis 91061|Bacilli H Thiamine monophosphate synthase thiE GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 ko:K00788 ko00730,ko01100,map00730,map01100 M00127 R03223,R10712 RC00224,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 - - - TMP-TENI k141_21592_1 1453501.JELR01000001_gene2381 5.67e-43 144.0 COG2165@1|root,COG2165@2|Bacteria,1N737@1224|Proteobacteria,1SC8X@1236|Gammaproteobacteria,468WY@72275|Alteromonadaceae 1236|Gammaproteobacteria NU General secretion pathway protein I gspI GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - ko:K02458 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - N_methyl,T2SSI k141_21592_2 1279017.AQYJ01000025_gene574 4.53e-84 258.0 COG4795@1|root,COG4795@2|Bacteria,1RJAE@1224|Proteobacteria,1S5ZZ@1236|Gammaproteobacteria,466QM@72275|Alteromonadaceae 1236|Gammaproteobacteria U General secretion pathway protein J gspJ GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0098776 - ko:K02459 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - N_methyl,T2SSJ k141_21592_3 1279017.AQYJ01000025_gene573 5.53e-73 230.0 COG3156@1|root,COG3156@2|Bacteria,1RAQM@1224|Proteobacteria,1S2N8@1236|Gammaproteobacteria,465H2@72275|Alteromonadaceae 1236|Gammaproteobacteria U COG3156 Type II secretory pathway, component PulK gspK GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - ko:K02460 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSK k141_25076_1 218284.CCDN010000001_gene1828 1.89e-205 578.0 COG0621@1|root,COG0621@2|Bacteria,1TNYN@1239|Firmicutes,4HAAS@91061|Bacilli,1ZBMF@1386|Bacillus 91061|Bacilli J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine miaB GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035597,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360 2.8.4.3 ko:K06168 - - R10645,R10646,R10647 RC00003,RC00980,RC03221,RC03222 ko00000,ko01000,ko03016 - - - Radical_SAM,TRAM,UPF0004 k141_10809_1 1294265.JCM21738_3694 7.2e-52 165.0 COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,4HAT6@91061|Bacilli,1ZB62@1386|Bacillus 91061|Bacilli C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits atpD - 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - iSB619.SA_RS10965 ATP-synt_ab,ATP-synt_ab_N k141_10809_2 1294265.JCM21738_3695 4.37e-82 244.0 COG0355@1|root,COG0355@2|Bacteria,1VA89@1239|Firmicutes,4HKHS@91061|Bacilli,1ZGET@1386|Bacillus 91061|Bacilli C Produces ATP from ADP in the presence of a proton gradient across the membrane atpC GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_DE,ATP-synt_DE_N k141_7282_1 1286632.P278_31300 9.56e-297 822.0 28HMZ@1|root,2Z7WD@2|Bacteria,4P095@976|Bacteroidetes 976|Bacteroidetes S Protein of unknown function (DUF3604) - - - - - - - - - - - - DUF3604 k141_7282_2 1348635.BBJY01000016_gene3963 4.26e-189 531.0 COG1172@1|root,COG1172@2|Bacteria,1MX7D@1224|Proteobacteria,1RNTS@1236|Gammaproteobacteria,1XTC8@135623|Vibrionales 135623|Vibrionales G Belongs to the binding-protein-dependent transport system permease family - - - ko:K02057 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - BPD_transp_2 k141_7282_3 1348635.BBJY01000016_gene3964 6.7e-173 489.0 COG1172@1|root,COG1172@2|Bacteria,1MX7D@1224|Proteobacteria,1RNTS@1236|Gammaproteobacteria,1XTC8@135623|Vibrionales 135623|Vibrionales G Belongs to the binding-protein-dependent transport system permease family - - - ko:K02057 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - BPD_transp_2 k141_33409_1 218284.CCDN010000001_gene526 1.61e-104 310.0 COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,4HGRC@91061|Bacilli,1ZC6X@1386|Bacillus 91061|Bacilli O HflC and HflK could regulate a protease hflC - - ko:K04087 - M00742 - - ko00000,ko00002,ko01000 - - - Band_7 k141_8503_2 218284.CCDN010000006_gene3770 1.51e-70 226.0 COG2247@1|root,COG2247@2|Bacteria 2|Bacteria M cell wall organization - - - - - - - - - - - - Big_2,CW_binding_2,LTD,Peptidase_S8 k141_28728_1 906888.JCM19314_2918 1.57e-34 129.0 COG1012@1|root,COG1012@2|Bacteria,4NFPJ@976|Bacteroidetes,1HX3I@117743|Flavobacteriia,3HK3I@363408|Nonlabens 976|Bacteroidetes C Aldehyde dehydrogenase family pcd - 1.2.1.3 ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_28728_2 546266.NEIMUCOT_05484 4.11e-24 100.0 COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,2VJ6H@28216|Betaproteobacteria,2KPX2@206351|Neisseriales 206351|Neisseriales F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor pyrD - 1.3.5.2 ko:K00254 ko00240,ko01100,map00240,map01100 M00051 R01868 RC00051 ko00000,ko00001,ko00002,ko01000 - - - DHO_dh k141_16790_1 666686.B1NLA3E_11295 3.63e-128 370.0 COG1307@1|root,COG1307@2|Bacteria,1TRZ4@1239|Firmicutes,4HBR8@91061|Bacilli,1ZM8T@1386|Bacillus 91061|Bacilli S Uncharacterised protein, DegV family COG1307 degV - - - - - - - - - - - DegV k141_23897_1 866895.HBHAL_1580 1.77e-62 199.0 COG0714@1|root,COG0714@2|Bacteria,1TPKR@1239|Firmicutes,4HA0T@91061|Bacilli,3NDE8@45667|Halobacillus 91061|Bacilli S ATPase family associated with various cellular activities (AAA) yeaC GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 k141_4899_1 1279017.AQYJ01000028_gene2415 5.86e-54 181.0 COG0265@1|root,COG0265@2|Bacteria,1NXB0@1224|Proteobacteria,1RRAD@1236|Gammaproteobacteria,465AC@72275|Alteromonadaceae 1236|Gammaproteobacteria O Trypsin-like peptidase domain - - - - - - - - - - - - Trypsin_2 k141_6152_1 1123008.KB905696_gene2957 2.95e-06 50.8 COG3015@1|root,COG3187@1|root,COG3015@2|Bacteria,COG3187@2|Bacteria,4NSEQ@976|Bacteroidetes,2FSUC@200643|Bacteroidia,22YXQ@171551|Porphyromonadaceae 976|Bacteroidetes MP NlpE N-terminal domain nlpE - - - - - - - - - - - META,NlpE k141_6152_2 1265503.KB905162_gene3651 6.08e-26 116.0 COG2199@1|root,COG3292@1|root,COG3292@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1RQCR@1236|Gammaproteobacteria,2Q7G0@267889|Colwelliaceae 1236|Gammaproteobacteria T Y_Y_Y domain - - - - - - - - - - - - GGDEF,Reg_prop,Y_Y_Y k141_6152_4 1116375.VEJY3_21241 1.05e-118 345.0 COG0583@1|root,COG0583@2|Bacteria,1MY68@1224|Proteobacteria,1RSEX@1236|Gammaproteobacteria,1XV82@135623|Vibrionales 135623|Vibrionales K Bacterial regulatory helix-turn-helix protein, lysR family - - - - - - - - - - - - HTH_1,LysR_substrate k141_25077_2 1453501.JELR01000002_gene864 8.77e-27 104.0 COG2808@1|root,COG2808@2|Bacteria,1N1B9@1224|Proteobacteria,1S7MT@1236|Gammaproteobacteria,4677D@72275|Alteromonadaceae 1236|Gammaproteobacteria K Putative FMN-binding domain paiB - - ko:K07734 - - - - ko00000,ko03000 - - - FMN_bind_2 k141_35769_1 566466.NOR53_721 1.63e-71 242.0 COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,1RMFJ@1236|Gammaproteobacteria,1J4YK@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H COG4206 Outer membrane cobalamin receptor protein btuB - - ko:K16092 - - - - ko00000,ko02000 1.B.14.3 - - Plug,TonB_dep_Rec k141_9642_2 218284.CCDN010000001_gene1092 1.01e-120 348.0 COG0283@1|root,COG0283@2|Bacteria,1V3IA@1239|Firmicutes,4HFZE@91061|Bacilli,1ZBXZ@1386|Bacillus 91061|Bacilli F Belongs to the cytidylate kinase family. Type 1 subfamily cmk GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 ko:K00945 ko00240,ko01100,map00240,map01100 M00052 R00158,R00512,R01665 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Cytidylate_kin k141_217_1 338963.Pcar_0699 2.07e-86 266.0 COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,42MWZ@68525|delta/epsilon subdivisions,2WJ2B@28221|Deltaproteobacteria,43U9V@69541|Desulfuromonadales 28221|Deltaproteobacteria J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis tuf - - ko:K02358 - - - - ko00000,ko03012,ko03029,ko04147 - - - GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 k141_21593_1 218284.CCDN010000001_gene1276 2.57e-83 263.0 28RY4@1|root,30CEX@2|Bacteria,1U9S3@1239|Firmicutes,4IJYG@91061|Bacilli,1ZNUD@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_28729_1 935836.JAEL01000017_gene815 3.01e-61 203.0 COG4263@1|root,COG4263@2|Bacteria,1UYT4@1239|Firmicutes,4HUEQ@91061|Bacilli,1ZE59@1386|Bacillus 91061|Bacilli C Cupredoxin-like domain nosZ - 1.7.2.4 ko:K00376 ko00910,ko01120,map00910,map01120 M00529 R02804 RC02861 ko00000,ko00001,ko00002,ko01000 - - - Cupredoxin_1 k141_13259_2 665952.HMPREF1015_02768 4.29e-28 102.0 COG1396@1|root,COG1396@2|Bacteria,1VIT6@1239|Firmicutes,4HP4J@91061|Bacilli,1ZJ4Q@1386|Bacillus 91061|Bacilli K transcriptional yazB - - - - - - - - - - - HTH_3 k141_13259_3 218284.CCDN010000003_gene3014 5.68e-115 330.0 COG0801@1|root,COG0801@2|Bacteria,1V6PR@1239|Firmicutes,4HIMG@91061|Bacilli,1ZGBC@1386|Bacillus 91061|Bacilli H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase folK - 2.7.6.3 ko:K00950 ko00790,ko01100,map00790,map01100 M00126,M00841 R03503 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - HPPK k141_3751_1 1042377.AFPJ01000037_gene2875 1.29e-79 241.0 COG3762@1|root,COG3762@2|Bacteria,1R61N@1224|Proteobacteria,1S2RR@1236|Gammaproteobacteria,466UH@72275|Alteromonadaceae 1236|Gammaproteobacteria S Membrane - - - ko:K08988 - - - - ko00000 - - - TPM_phosphatase k141_3751_2 1453501.JELR01000001_gene1968 2.45e-100 299.0 COG1512@1|root,COG1512@2|Bacteria,1PB41@1224|Proteobacteria,1S38U@1236|Gammaproteobacteria,466VG@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG1512 Beta-propeller domains of methanol dehydrogenase type Z012_08980 - - ko:K06872 - - - - ko00000 - - - TPM_phosphatase k141_3751_3 1042377.AFPJ01000037_gene2873 1.4e-23 94.4 COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,1RS3E@1236|Gammaproteobacteria,466K8@72275|Alteromonadaceae 1236|Gammaproteobacteria S LemA family lemA - - ko:K03744 - - - - ko00000 - - - LemA k141_23898_1 1042377.AFPJ01000030_gene468 3.82e-44 146.0 COG2891@1|root,COG2891@2|Bacteria,1RER7@1224|Proteobacteria,1S8VI@1236|Gammaproteobacteria,468E3@72275|Alteromonadaceae 1236|Gammaproteobacteria M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins mreD GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944 - ko:K03571 - - - - ko00000,ko03036 9.B.157.1 - - MreD k141_26346_1 1078085.HMPREF1210_03319 7.9e-13 70.1 28PM4@1|root,2ZCA8@2|Bacteria,1V1PA@1239|Firmicutes,4HFNN@91061|Bacilli,26G42@186818|Planococcaceae 91061|Bacilli S YtkA-like - - - - - - - - - - - - YtkA k141_26346_2 1230341.MJ3_07868 2.35e-11 58.5 2C2JF@1|root,33CZ0@2|Bacteria,1VN4G@1239|Firmicutes,4HR1T@91061|Bacilli 91061|Bacilli S YhfH-like protein yhfH - - - - - - - - - - - YhfH k141_7283_2 218284.CCDN010000002_gene2237 8.77e-124 369.0 COG3275@1|root,COG3275@2|Bacteria,1VTXF@1239|Firmicutes,4H9Z1@91061|Bacilli,1ZBKQ@1386|Bacillus 91061|Bacilli T Histidine kinase lytS - 2.7.13.3 ko:K07704 ko02020,map02020 M00492 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - 5TM-5TMR_LYT,GAF_3,HATPase_c,His_kinase k141_9643_1 913865.DOT_5617 5.75e-37 142.0 COG2755@1|root,COG2755@2|Bacteria 2|Bacteria E lipolytic protein G-D-S-L family envE - 3.1.4.46,3.2.1.18,3.2.1.8 ko:K01126,ko:K01181,ko:K01186 ko00511,ko00564,ko00600,ko04142,map00511,map00564,map00600,map04142 - R01030,R01470,R04018 RC00017,RC00028,RC00077,RC00425 ko00000,ko00001,ko01000,ko02042 - GH33 - GHL10,Lipase_GDSL_2,RicinB_lectin_2,Ricin_B_lectin,SLH k141_34638_1 1294265.JCM21738_446 3.25e-99 294.0 COG1737@1|root,COG1737@2|Bacteria,1TR0N@1239|Firmicutes,4HB9E@91061|Bacilli,1ZCCD@1386|Bacillus 91061|Bacilli K RpiR family transcriptional regulator gntR - - - - - - - - - - - HTH_6,SIS k141_10810_1 218284.CCDN010000002_gene2271 2.34e-119 349.0 COG1902@1|root,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,4HAS5@91061|Bacilli,1ZB1N@1386|Bacillus 91061|Bacilli C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family yqiG - - - - - - - - - - - Oxidored_FMN k141_4901_1 218284.CCDN010000001_gene176 3.3e-14 71.2 COG0318@1|root,COG0318@2|Bacteria,1V2NE@1239|Firmicutes,4HBPA@91061|Bacilli,1ZDIG@1386|Bacillus 91061|Bacilli IQ PFAM AMP-dependent synthetase and ligase - - - - - - - - - - - - - k141_4901_2 218284.CCDN010000001_gene175 1.58e-91 275.0 COG1131@1|root,COG1131@2|Bacteria,1TQUS@1239|Firmicutes,4IPX9@91061|Bacilli,1ZDPX@1386|Bacillus 91061|Bacilli V ATPases associated with a variety of cellular activities - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 k141_35770_2 1089550.ATTH01000001_gene695 4.12e-59 197.0 COG3200@1|root,COG3200@2|Bacteria,4PEX3@976|Bacteroidetes,1FJS4@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes E Class-II DAHP synthetase family - - 2.5.1.54 ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 - - - DAHP_synth_2 k141_218_1 1461580.CCAS010000004_gene540 9.03e-80 248.0 COG0130@1|root,COG0130@2|Bacteria,1TP9Y@1239|Firmicutes,4HA9X@91061|Bacilli,1ZBKE@1386|Bacillus 91061|Bacilli J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs truB GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 ko:K03177,ko:K03483 - - - - ko00000,ko01000,ko03000,ko03016 - - iSB619.SA_RS06305 TruB-C_2,TruB_C_2,TruB_N k141_16792_1 218284.CCDN010000002_gene2139 4.87e-149 430.0 COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,4HADT@91061|Bacilli,1ZC5H@1386|Bacillus 91061|Bacilli KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains - - - - - - - - - - - - HTH_8,PAS_4,PAS_9,Sigma54_activat k141_219_1 558169.AGAV01000015_gene588 6.38e-15 73.6 COG0025@1|root,COG0025@2|Bacteria,1U8X3@1239|Firmicutes,4HBQR@91061|Bacilli 91061|Bacilli P COG0025 NhaP-type Na H and K H antiporters - - - - - - - - - - - - Na_H_Exchanger,TrkA_N k141_34640_1 1301100.HG529366_gene1359 1.03e-76 247.0 COG0481@1|root,COG0481@2|Bacteria,1TP0G@1239|Firmicutes,247V8@186801|Clostridia,36EZX@31979|Clostridiaceae 186801|Clostridia M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner lepA - - ko:K03596 ko05134,map05134 - - - ko00000,ko00001 - - - EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C k141_14441_1 1279017.AQYJ01000020_gene1365 0.0 1353.0 COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,1RMQE@1236|Gammaproteobacteria,464C0@72275|Alteromonadaceae 1236|Gammaproteobacteria J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs rnr GO:0000175,GO:0003674,GO:0003724,GO:0003824,GO:0004386,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008408,GO:0008997,GO:0009056,GO:0009057,GO:0009266,GO:0009409,GO:0009628,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016896,GO:0017111,GO:0019222,GO:0019439,GO:0034458,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - ko:K12573 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03016,ko03019 - - - HTH_12,OB_RNB,RNB,S1 k141_7284_1 265729.GS18_0206925 7.34e-11 58.5 2DRDP@1|root,33BB6@2|Bacteria,1VD3J@1239|Firmicutes,4HNDU@91061|Bacilli,1ZI2X@1386|Bacillus 91061|Bacilli S Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth - - - - - - - - - - - - Gas_vesicle k141_7284_2 265729.GS18_0206920 2.72e-46 150.0 arCOG06390@1|root,330IR@2|Bacteria,1VCE0@1239|Firmicutes,4HM08@91061|Bacilli,1ZIFA@1386|Bacillus 91061|Bacilli S Gas vesicle protein K gvpK - - - - - - - - - - - GvpK k141_4902_1 568816.Acin_1796 3.81e-20 96.3 COG0381@1|root,COG0381@2|Bacteria,1TQZT@1239|Firmicutes,4H2UD@909932|Negativicutes 909932|Negativicutes G Belongs to the UDP-N-acetylglucosamine 2-epimerase family mnaA - 5.1.3.14 ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 M00362 R00420 RC00290 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Epimerase_2 k141_4902_2 396588.Tgr7_0794 1.18e-06 49.7 COG0463@1|root,COG0463@2|Bacteria,1MXC1@1224|Proteobacteria,1RRHP@1236|Gammaproteobacteria,1WXRS@135613|Chromatiales 135613|Chromatiales M PFAM Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 k141_15645_2 1042377.AFPJ01000051_gene110 2.81e-158 451.0 COG0598@1|root,COG0598@2|Bacteria,1MWMP@1224|Proteobacteria,1RNDQ@1236|Gammaproteobacteria,465JG@72275|Alteromonadaceae 1236|Gammaproteobacteria P Mediates influx of magnesium ions corA GO:0000041,GO:0003674,GO:0005215,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0008150,GO:0008324,GO:0015075,GO:0015087,GO:0015095,GO:0015099,GO:0015318,GO:0015675,GO:0015693,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0035444,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:1903830 - ko:K03284 - - - - ko00000,ko02000 1.A.35.1,1.A.35.3 - iYL1228.KPN_04313 CorA k141_15645_3 1279017.AQYJ01000028_gene2424 6.14e-64 199.0 COG5622@1|root,COG5622@2|Bacteria,1N6XP@1224|Proteobacteria,1SCD9@1236|Gammaproteobacteria,4691R@72275|Alteromonadaceae 1236|Gammaproteobacteria N Protein required for attachment to host cells - - - - - - - - - - - - Host_attach k141_15645_4 1279017.AQYJ01000028_gene2425 2.61e-62 195.0 COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,1S607@1236|Gammaproteobacteria,468FQ@72275|Alteromonadaceae 1236|Gammaproteobacteria O Belongs to the small heat shock protein (HSP20) family - - - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 k141_15645_5 1279017.AQYJ01000028_gene2426 2.23e-20 84.0 COG0517@1|root,COG0517@2|Bacteria,1QTVM@1224|Proteobacteria,1SFWU@1236|Gammaproteobacteria,46BCN@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain in cystathionine beta-synthase and other proteins. - - - - - - - - - - - - CBS k141_12027_1 1219076.N646_0485 1.39e-29 106.0 2AWN3@1|root,31NIV@2|Bacteria,1QK9H@1224|Proteobacteria,1TID0@1236|Gammaproteobacteria,1XYWJ@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_12027_2 1116375.VEJY3_06935 7.22e-230 637.0 COG2203@1|root,COG2206@1|root,COG2203@2|Bacteria,COG2206@2|Bacteria,1RAQS@1224|Proteobacteria,1T1XS@1236|Gammaproteobacteria,1XUFB@135623|Vibrionales 135623|Vibrionales T HD domain - - - - - - - - - - - - GAF_2,HD_5 k141_12027_3 1116375.VEJY3_06930 3.15e-249 688.0 COG0814@1|root,COG0814@2|Bacteria,1N35H@1224|Proteobacteria,1RNNC@1236|Gammaproteobacteria,1XSRG@135623|Vibrionales 135623|Vibrionales U tyrosine-specific transport protein tyrP - - ko:K03834 - - - - ko00000,ko02000 2.A.42.1.1 - - Trp_Tyr_perm k141_12027_4 1280001.BAOA01000126_gene1155 1.76e-151 431.0 COG3637@1|root,COG3637@2|Bacteria,1N7AR@1224|Proteobacteria,1SG7N@1236|Gammaproteobacteria,1XXFP@135623|Vibrionales 135623|Vibrionales M Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - - - - - - - - - - DUF481 k141_12027_5 223926.28806413 9.84e-131 372.0 COG3751@1|root,COG3751@2|Bacteria,1RD3H@1224|Proteobacteria,1S40I@1236|Gammaproteobacteria,1XSQS@135623|Vibrionales 135623|Vibrionales O Prolyl 4-hydroxylase alpha subunit homologues. - - - ko:K07394 - - - - ko00000 - - - 2OG-FeII_Oxy_3 k141_12027_6 1116375.VEJY3_06920 1.2e-194 542.0 COG0583@1|root,COG0583@2|Bacteria,1N663@1224|Proteobacteria,1SN55@1236|Gammaproteobacteria,1XVSU@135623|Vibrionales 135623|Vibrionales K Transcriptional regulator VV2061 - - - - - - - - - - - HTH_1,LysR_substrate k141_27481_2 218284.CCDN010000001_gene1347 7.7e-51 167.0 COG0706@1|root,COG0706@2|Bacteria,1TSDN@1239|Firmicutes,4HCC8@91061|Bacilli,1ZE6C@1386|Bacillus 91061|Bacilli U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins yidC - - ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 - - 60KD_IMP k141_33427_1 42565.FP66_00575 1.52e-43 147.0 COG4598@1|root,COG4598@2|Bacteria,1QTS2@1224|Proteobacteria,1RQYN@1236|Gammaproteobacteria,1XHMI@135619|Oceanospirillales 135619|Oceanospirillales E ATP-binding protein - - 3.6.3.21 ko:K02028,ko:K10025 ko02010,map02010 M00235,M00236 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3,3.A.1.3.11 - - ABC_tran k141_33427_2 42565.FP66_00580 1.1e-70 218.0 COG4215@1|root,COG4215@2|Bacteria,1MY2N@1224|Proteobacteria,1RNYD@1236|Gammaproteobacteria,1XIVF@135619|Oceanospirillales 135619|Oceanospirillales E (ABC) transporter - - - ko:K10016,ko:K10024 ko02010,map02010 M00225,M00226,M00235 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.1,3.A.1.3.11 - - BPD_transp_1 k141_12053_1 218284.CCDN010000001_gene107 6.28e-98 295.0 COG3314@1|root,COG3314@2|Bacteria,1TR0V@1239|Firmicutes,4HB55@91061|Bacilli,1ZCCT@1386|Bacillus 91061|Bacilli S Sporulation integral membrane protein YlbJ ylbJ - - - - - - - - - - - Gate k141_36986_1 218284.CCDN010000007_gene3946 7.57e-120 362.0 COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H9SA@91061|Bacilli,1ZBUK@1386|Bacillus 91061|Bacilli M penicillin-binding protein pbpG GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.4.1.129,3.4.16.4 ko:K21464 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase k141_21612_1 218284.CCDN010000008_gene4261 6.4e-120 346.0 COG1309@1|root,COG1309@2|Bacteria,1V6TA@1239|Firmicutes,4HISQ@91061|Bacilli,1ZGRH@1386|Bacillus 91061|Bacilli K Transcriptional regulator yttP GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - - - - - - - - - - TetR_N k141_10827_1 935837.JAEK01000050_gene945 6.05e-07 50.8 COG3910@1|root,COG3910@2|Bacteria,1TSWP@1239|Firmicutes,4HBQT@91061|Bacilli,1ZCVC@1386|Bacillus 91061|Bacilli S AAA domain cysA1 - - - - - - - - - - - AAA_21,AAA_23 k141_7314_1 1196028.ALEF01000060_gene1203 1.71e-108 327.0 COG0591@1|root,COG0591@2|Bacteria,1TRK6@1239|Firmicutes,4HEE9@91061|Bacilli,4C4V4@84406|Virgibacillus 91061|Bacilli E Sodium:solute symporter family - - - ko:K11928,ko:K14392 - - - - ko00000,ko02000 2.A.21.1,2.A.21.2 - - SSF k141_1319_1 218284.CCDN010000002_gene1988 6.14e-117 354.0 COG0046@1|root,COG0046@2|Bacteria,1TPAS@1239|Firmicutes,4HB3N@91061|Bacilli,1ZCN8@1386|Bacillus 91061|Bacilli F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL purL GO:0003674,GO:0003824,GO:0004642,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C k141_244_1 1121926.AXWO01000038_gene2549 1.77e-28 117.0 COG3509@1|root,COG3509@2|Bacteria,2GMTA@201174|Actinobacteria 201174|Actinobacteria Q Esterase, phb depolymerase family - - - - - - - - - - - - CBM_2,Esterase_phd k141_27482_1 218284.CCDN010000001_gene1342 3.39e-96 295.0 COG0025@1|root,COG0025@2|Bacteria,1TR4G@1239|Firmicutes,4HBJR@91061|Bacilli,1ZQCF@1386|Bacillus 91061|Bacilli P Sodium/hydrogen exchanger family - - - ko:K03316 - - - - ko00000 2.A.36 - - Na_H_Exchanger k141_5118_1 1279017.AQYJ01000029_gene3822 2.08e-31 119.0 COG2850@1|root,COG2850@2|Bacteria,1MW30@1224|Proteobacteria,1RN2Q@1236|Gammaproteobacteria,464Y7@72275|Alteromonadaceae 1236|Gammaproteobacteria S A domain family that is part of the cupin metalloenzyme superfamily. ycfD GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0016491,GO:0016705,GO:0016706,GO:0018193,GO:0018195,GO:0019538,GO:0030961,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046872,GO:0046914,GO:0051213,GO:0055114,GO:0071704,GO:1901564 1.14.11.47 ko:K18850 - - - - ko00000,ko01000,ko03009 - - - Cupin_4 k141_5118_2 863239.AFIZ01000024_gene2603 6.68e-16 77.0 COG2153@1|root,COG2153@2|Bacteria,2HJAN@201174|Actinobacteria,22NQB@1653|Corynebacteriaceae 201174|Actinobacteria S Acetyltransferase (GNAT) domain - - - ko:K02348 - - - - ko00000 - - - Acetyltransf_10 k141_5118_3 1042377.AFPJ01000007_gene1767 1.13e-22 95.1 COG2153@1|root,COG2153@2|Bacteria,1MZ86@1224|Proteobacteria,1S8SK@1236|Gammaproteobacteria,467WF@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - - - - - - - - - - Acetyltransf_10 k141_37153_1 1405.DJ92_3919 3.96e-12 67.0 COG4974@1|root,COG4974@2|Bacteria,1TRZV@1239|Firmicutes,4HCBD@91061|Bacilli,1ZQ0P@1386|Bacillus 91061|Bacilli L Phage integrase family - - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_int_SAM_4,Phage_int_SAM_5,Phage_integrase k141_31281_1 765952.PUV_00830 3.24e-70 225.0 COG0861@1|root,COG0861@2|Bacteria,2JGY6@204428|Chlamydiae 204428|Chlamydiae P Integral membrane protein TerC family - - - ko:K05794 - - - - ko00000 - - - TerC k141_18255_1 1042377.AFPJ01000009_gene319 1.17e-100 313.0 COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,1RMXI@1236|Gammaproteobacteria,464BP@72275|Alteromonadaceae 1236|Gammaproteobacteria E Peptidase family M3 dcp - 3.4.15.5 ko:K01284 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M3 k141_32366_1 1347086.CCBA010000034_gene2576 4.33e-25 109.0 COG0577@1|root,COG0577@2|Bacteria,1URMS@1239|Firmicutes,4HCC6@91061|Bacilli,1ZAQ4@1386|Bacillus 91061|Bacilli V efflux transmembrane transporter activity - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX k141_23031_1 42565.FP66_05800 2.83e-85 271.0 COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria 1224|Proteobacteria T Diguanylate cyclase - - - - - - - - - - - - GGDEF,MASE1 k141_29997_1 745277.GRAQ_02754 1.86e-58 192.0 COG1957@1|root,COG1957@2|Bacteria,1R49G@1224|Proteobacteria,1RZM4@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Belongs to the IUNH family - - - - - - - - - - - - IU_nuc_hydro k141_29997_2 1196095.GAPWK_2309 1.5e-22 96.3 COG0524@1|root,COG1349@1|root,COG0524@2|Bacteria,COG1349@2|Bacteria,1R52G@1224|Proteobacteria,1RN4W@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway - - - - - - - - - - - - HTH_DeoR,PfkB k141_19384_1 1449063.JMLS01000003_gene1947 9.74e-43 152.0 COG1014@1|root,COG1144@1|root,COG1014@2|Bacteria,COG1144@2|Bacteria,1TRFJ@1239|Firmicutes,4HBXC@91061|Bacilli,26T0J@186822|Paenibacillaceae 91061|Bacilli C ferredoxin porC - 1.2.7.1 ko:K00172 ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200 M00173,M00307,M00374,M00620 R01196,R01199,R08034 RC00004,RC00250,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - Fer4,Fer4_10,Fer4_6,Fer4_7,POR k141_17015_1 1294265.JCM21738_2751 6.07e-87 256.0 2DV4S@1|root,32UYM@2|Bacteria,1VA7R@1239|Firmicutes,4HMUX@91061|Bacilli,1ZI1G@1386|Bacillus 91061|Bacilli S Putative coat protein ylbD - - - - - - - - - - - YlbD_coat k141_17015_2 1294265.JCM21738_2752 2.47e-11 58.5 2ED1C@1|root,336YB@2|Bacteria,1VJ46@1239|Firmicutes,4HPWX@91061|Bacilli,1ZJ6S@1386|Bacillus 91061|Bacilli S YlbE-like protein ylbE - - - - - - - - - - - YlbE k141_21782_1 1453501.JELR01000002_gene952 1.73e-168 525.0 COG0643@1|root,COG0745@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,4650G@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0643 Chemotaxis protein histidine kinase and related kinases chpA - - ko:K02487,ko:K06596 ko02020,ko02025,map02020,map02025 M00507 - - ko00000,ko00001,ko00002,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg k141_26723_1 218284.CCDN010000001_gene129 1.08e-134 389.0 COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,1TRC3@1239|Firmicutes,4HADQ@91061|Bacilli,1ZAP8@1386|Bacillus 91061|Bacilli C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) ctaC GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.9.3.1 ko:K02275 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.4,3.D.4.6 - - COX2,COX2_TM,Cytochrom_C,Cytochrome_CBB3 k141_9915_1 218284.CCDN010000003_gene3007 2.12e-11 65.1 COG0760@1|root,COG0760@2|Bacteria,1UZZM@1239|Firmicutes,4HE14@91061|Bacilli,1ZBFZ@1386|Bacillus 91061|Bacilli O peptidyl-prolyl isomerase yacD - 5.2.1.8 ko:K07533 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_2,Rotamase_3,SurA_N_3 k141_13555_1 1453501.JELR01000001_gene1972 8.78e-07 51.6 COG4222@1|root,COG4222@2|Bacteria,1NRU1@1224|Proteobacteria,1SM0C@1236|Gammaproteobacteria 1236|Gammaproteobacteria S DNA topoisomerase IV subunit B - - - - - - - - - - - - Phytase-like k141_15833_1 545693.BMQ_5248 3.02e-125 375.0 COG3211@1|root,COG3211@2|Bacteria,1UYPE@1239|Firmicutes,4HCRC@91061|Bacilli,1ZDBG@1386|Bacillus 91061|Bacilli N Bacterial protein of unknown function (DUF839) - - - ko:K07093 - - - - ko00000 - - - DUF839 k141_33687_1 1122599.AUGR01000002_gene3265 2.24e-16 77.0 COG2863@1|root,COG2863@2|Bacteria,1N2NB@1224|Proteobacteria,1RZFP@1236|Gammaproteobacteria,1XI5C@135619|Oceanospirillales 135619|Oceanospirillales C COG2863 Cytochrome c553 cc4 - - - - - - - - - - - Cytochrom_C,Cytochrome_CBB3 k141_33687_2 686340.Metal_0170 3.51e-14 75.5 COG1651@1|root,COG1651@2|Bacteria,1RGWH@1224|Proteobacteria,1S5WA@1236|Gammaproteobacteria,1XEWA@135618|Methylococcales 135618|Methylococcales O Thiol disulfide interchange protein dsbA - - ko:K03673 ko01503,map01503 M00728 - - ko00000,ko00001,ko00002,ko03110 - - - DSBA k141_5119_1 1294265.JCM21738_1917 2.76e-51 164.0 2E3PJ@1|root,32YMN@2|Bacteria,1VGBJ@1239|Firmicutes,4HNU4@91061|Bacilli,1ZIVU@1386|Bacillus 91061|Bacilli S Belongs to the UPF0738 family yjbL - - - - - - - - - - - - k141_5119_2 1294265.JCM21738_1916 1.87e-91 270.0 COG2357@1|root,COG2357@2|Bacteria,1TQ2F@1239|Firmicutes,4HA3Q@91061|Bacilli,1ZBM8@1386|Bacillus 91061|Bacilli S GTP pyrophosphokinase yjbM GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5 ko:K07816 ko00230,map00230 - R00429 RC00002,RC00078 ko00000,ko00001,ko01000 - - - RelA_SpoT k141_18256_2 1044.EH31_08195 0.000567 41.6 COG4146@1|root,COG4146@2|Bacteria,1MXWV@1224|Proteobacteria,2U1ED@28211|Alphaproteobacteria,2KDAS@204457|Sphingomonadales 204457|Sphingomonadales S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - ko:K03307 - - - - ko00000 2.A.21 - - SSF k141_19385_1 218284.CCDN010000001_gene646 5.14e-118 345.0 COG0510@1|root,COG0510@2|Bacteria,1VB8C@1239|Firmicutes,4HNC9@91061|Bacilli,1ZAQ0@1386|Bacillus 91061|Bacilli M choline kinase involved in LPS biosynthesis - - - - - - - - - - - - APH k141_14607_1 1294265.JCM21738_1711 4.45e-13 66.6 COG0671@1|root,COG0671@2|Bacteria,1V2ZH@1239|Firmicutes,4HMGP@91061|Bacilli,1ZRR2@1386|Bacillus 91061|Bacilli I PAP2 superfamily - - - - - - - - - - - - PAP2,PAP2_3 k141_14607_2 1294265.JCM21738_1709 2.42e-36 127.0 2E4BW@1|root,32Z7G@2|Bacteria,1VH0F@1239|Firmicutes,4HPQD@91061|Bacilli,1ZINT@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2512) yndM - - - - - - - - - - - DUF2512 k141_9916_1 1294265.JCM21738_3641 1.28e-49 171.0 COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,4HACG@91061|Bacilli,1ZBBF@1386|Bacillus 91061|Bacilli S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid yabM GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03328 - - - - ko00000 2.A.66.2 - - Polysacc_synt,Polysacc_synt_C k141_9916_2 997296.PB1_06957 1.6e-28 113.0 COG1694@1|root,COG3956@2|Bacteria,1TPK1@1239|Firmicutes,4HA0A@91061|Bacilli,1ZAYB@1386|Bacillus 91061|Bacilli S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like yabN GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.66 ko:K02428,ko:K02499 ko00230,map00230 - R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000,ko03036 - - - MazG,TP_methylase k141_2756_1 1042377.AFPJ01000014_gene1679 1.7e-78 238.0 COG2980@1|root,COG2980@2|Bacteria,1NGPX@1224|Proteobacteria,1SGKQ@1236|Gammaproteobacteria,4692K@72275|Alteromonadaceae 1236|Gammaproteobacteria M Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane lptE - - ko:K03643 - - - - ko00000,ko02000 1.B.42.1 - - LptE k141_2756_2 1453501.JELR01000001_gene2977 1.57e-191 537.0 COG1466@1|root,COG1466@2|Bacteria,1MWYT@1224|Proteobacteria,1RQRE@1236|Gammaproteobacteria,466B8@72275|Alteromonadaceae 1236|Gammaproteobacteria L DNA polymerase III, delta subunit holA GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delt_C,DNA_pol3_delta k141_31282_1 218284.CCDN010000001_gene1120 2.67e-89 268.0 2E49C@1|root,32Z54@2|Bacteria,1VH6M@1239|Firmicutes,4HQD6@91061|Bacilli,1ZDJG@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_506_1 1294265.JCM21738_1787 3.38e-145 413.0 COG1526@1|root,COG1526@2|Bacteria,1TU8R@1239|Firmicutes,4HAY8@91061|Bacilli,1ZBNJ@1386|Bacillus 91061|Bacilli C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH - - - ko:K02379 - - - - ko00000 - - - FdhD-NarQ k141_33707_1 29495.EA26_03790 1.41e-77 242.0 COG2224@1|root,COG2224@2|Bacteria,1MWIF@1224|Proteobacteria,1RQAK@1236|Gammaproteobacteria,1XTHW@135623|Vibrionales 135623|Vibrionales C Isocitrate lyase aceA - 4.1.3.1 ko:K01637 ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200 M00012 R00479 RC00311,RC00313 ko00000,ko00001,ko00002,ko01000 - - - ICL k141_33707_2 1116375.VEJY3_02675 4.87e-94 275.0 COG0517@1|root,COG0517@2|Bacteria,1N0EB@1224|Proteobacteria,1S9TG@1236|Gammaproteobacteria,1XX1F@135623|Vibrionales 135623|Vibrionales S acetoin utilization protein - - - - - - - - - - - - CBS k141_33707_3 1116375.VEJY3_02680 3.74e-235 651.0 COG5640@1|root,COG5640@2|Bacteria,1QJHF@1224|Proteobacteria,1THHB@1236|Gammaproteobacteria,1XVVF@135623|Vibrionales 135623|Vibrionales M Trypsin-like serine protease - - - - - - - - - - - - Trypsin k141_33707_4 1116375.VEJY3_02685 7.38e-251 688.0 COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,1RMKW@1236|Gammaproteobacteria,1XTWP@135623|Vibrionales 135623|Vibrionales F Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) queA GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 ko:K07568 - - - - ko00000,ko01000,ko03016 - - - Queuosine_synth k141_33707_5 1116375.VEJY3_02690 1.58e-286 781.0 COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,1RMY3@1236|Gammaproteobacteria,1XTCG@135623|Vibrionales 135623|Vibrionales F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) tgt GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008479,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 ko:K00773 - - R03789,R10209 RC00063 ko00000,ko01000,ko03016 - - - TGT k141_33707_6 1280001.BAOA01000085_gene3586 1.39e-68 207.0 COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,1S9NV@1236|Gammaproteobacteria,1XXBH@135623|Vibrionales 135623|Vibrionales U Preprotein translocase subunit YajC yajC - - ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - YajC k141_33707_7 1116375.VEJY3_02700 0.0 1082.0 COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,1RMIQ@1236|Gammaproteobacteria,1XSE8@135623|Vibrionales 135623|Vibrionales U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secD - - ko:K03072 ko03060,ko03070,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD-TM1,SecD_SecF,Sec_GG k141_4049_1 344747.PM8797T_03249 1.05e-47 164.0 COG0500@1|root,COG2226@2|Bacteria,2IZZG@203682|Planctomycetes 203682|Planctomycetes Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_25 k141_5148_1 1122134.KB893650_gene31 1.18e-79 245.0 COG2159@1|root,COG2159@2|Bacteria,1R5PG@1224|Proteobacteria,1RX6Z@1236|Gammaproteobacteria,1XRR2@135619|Oceanospirillales 135619|Oceanospirillales S Amidohydrolase - - 4.1.1.45 ko:K03392 ko00380,ko01100,map00380,map01100 M00038 R04323 RC00779 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_2 k141_5148_2 1219375.CM002139_gene3174 4.82e-75 229.0 COG0662@1|root,COG0662@2|Bacteria,1R4UW@1224|Proteobacteria,1S3Z7@1236|Gammaproteobacteria,1X6A0@135614|Xanthomonadales 135614|Xanthomonadales F Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate nbaC - 1.13.11.6 ko:K00452 ko00380,ko01100,map00380,map01100 M00038 R02665 RC00387 ko00000,ko00001,ko00002,ko01000 - - - 3-HAO k141_12402_1 218284.CCDN010000001_gene135 3.73e-86 262.0 COG2066@1|root,COG2066@2|Bacteria,1TP64@1239|Firmicutes,4H9XA@91061|Bacilli,1ZBXX@1386|Bacillus 91061|Bacilli E Belongs to the glutaminase family glsA GO:0003674,GO:0003824,GO:0004359,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006543,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009064,GO:0009065,GO:0009084,GO:0009987,GO:0016053,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 3.5.1.2 ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 - R00256,R01579 RC00010,RC02798 ko00000,ko00001,ko01000 - - - Glutaminase k141_12402_2 1196031.ALEG01000039_gene1502 1.08e-69 214.0 COG2041@1|root,COG2041@2|Bacteria,1V1EZ@1239|Firmicutes,4HIWI@91061|Bacilli,1ZDPV@1386|Bacillus 91061|Bacilli S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide ylaL - - - - - - - - - - - - k141_8772_1 1078085.HMPREF1210_02160 5.05e-113 328.0 COG0546@1|root,COG0546@2|Bacteria,1V1FQ@1239|Firmicutes,4HDVJ@91061|Bacilli,26F3Y@186818|Planococcaceae 91061|Bacilli S HAD-hyrolase-like nt5e - 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 - R01334 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 k141_26742_1 1236959.BAMT01000001_gene1427 7.79e-19 92.4 COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,2VI0H@28216|Betaproteobacteria,2KKX6@206350|Nitrosomonadales 206350|Nitrosomonadales H Belongs to the folylpolyglutamate synthase family - - 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 - - - Mur_ligase_C,Mur_ligase_M k141_26742_2 1453501.JELR01000001_gene1839 2.45e-60 195.0 COG3147@1|root,COG3147@2|Bacteria,1NGE3@1224|Proteobacteria,1SCGC@1236|Gammaproteobacteria,46CSJ@72275|Alteromonadaceae 1236|Gammaproteobacteria S Sporulation related domain dedD - - ko:K03749 - - - - ko00000 - - - SPOR k141_33708_1 218284.CCDN010000006_gene3737 1.45e-56 182.0 COG1464@1|root,COG1464@2|Bacteria,1TRXS@1239|Firmicutes,4HAD4@91061|Bacilli,1ZBWI@1386|Bacillus 91061|Bacilli P COG1464 ABC-type metal ion transport system, periplasmic component surface antigen - - - ko:K02073 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - Lipoprotein_9 k141_7484_2 218284.CCDN010000005_gene3166 3.66e-62 202.0 COG0420@1|root,COG0420@2|Bacteria,1TWMI@1239|Firmicutes,4HCA0@91061|Bacilli,1ZC5G@1386|Bacillus 91061|Bacilli L DNA repair exonuclease yhaO - - ko:K03547 - - - - ko00000,ko03400 - - - Metallophos,Metallophos_2 k141_23059_1 1042377.AFPJ01000004_gene406 3.19e-185 540.0 COG1629@1|root,COG4771@2|Bacteria,1MUWN@1224|Proteobacteria,1RN1E@1236|Gammaproteobacteria,464FG@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec k141_507_1 218284.CCDN010000006_gene3759 7.51e-168 471.0 COG1116@1|root,COG1116@2|Bacteria,1TRM6@1239|Firmicutes,4HAJC@91061|Bacilli,1ZCC8@1386|Bacillus 91061|Bacilli P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component ssuB - - ko:K02049 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - ABC_tran k141_507_2 218284.CCDN010000006_gene3760 4e-19 83.6 COG0600@1|root,COG0600@2|Bacteria,1TR9N@1239|Firmicutes,4HC2U@91061|Bacilli,1ZQFP@1386|Bacillus 91061|Bacilli P Binding-protein-dependent transport system inner membrane component ssuC_2 - - ko:K02050,ko:K15554 ko00920,ko02010,map00920,map02010 M00188,M00436 - - ko00000,ko00001,ko00002,ko02000 3.A.1.16,3.A.1.17,3.A.1.17.2 - - BPD_transp_1 k141_31286_2 1116375.VEJY3_23806 1.26e-255 705.0 COG0477@1|root,COG2814@2|Bacteria,1R91P@1224|Proteobacteria,1RMVM@1236|Gammaproteobacteria,1XV55@135623|Vibrionales 135623|Vibrionales EGP COG0477 Permeases of the major facilitator superfamily - - - - - - - - - - - - MFS_1 k141_31286_3 1116375.VEJY3_23801 3.77e-119 344.0 COG1961@1|root,COG1961@2|Bacteria,1R77A@1224|Proteobacteria,1T9IP@1236|Gammaproteobacteria,1XVZE@135623|Vibrionales 135623|Vibrionales L COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - - - - - - - - - - HTH_23,HTH_7,Resolvase k141_31286_4 1116375.VEJY3_23786 0.0 1284.0 COG1523@1|root,COG1523@2|Bacteria,1MU19@1224|Proteobacteria,1RP6F@1236|Gammaproteobacteria,1XTF4@135623|Vibrionales 135623|Vibrionales G Belongs to the glycosyl hydrolase 13 family glgX - 3.2.1.68 ko:K01214 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R09995,R11261 - ko00000,ko00001,ko00002,ko01000 - CBM48,GH13 - Alpha-amylase,CBM_48 k141_31286_5 1187848.AJYQ01000156_gene3762 2.03e-193 548.0 COG4580@1|root,COG4580@2|Bacteria,1MX77@1224|Proteobacteria,1RPMF@1236|Gammaproteobacteria,1XU0M@135623|Vibrionales 135623|Vibrionales M Involved in the transport of maltose and maltodextrins lamB GO:0003674,GO:0005215,GO:0005363,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015154,GO:0015157,GO:0015267,GO:0015288,GO:0015481,GO:0015766,GO:0015768,GO:0015772,GO:0022803,GO:0022829,GO:0022857,GO:0034219,GO:0051179,GO:0051234,GO:0055085,GO:0071702 - ko:K02024 - - - - ko00000,ko02000 1.B.3.1.1 - - LamB k141_31286_6 1187848.AJYQ01000156_gene3761 1.85e-99 301.0 2C19D@1|root,2Z7PA@2|Bacteria,1MY1F@1224|Proteobacteria,1RQ3A@1236|Gammaproteobacteria,1XUFJ@135623|Vibrionales 135623|Vibrionales S Maltose operon periplasmic protein precursor (MalM) malM - - ko:K05775 - - - - ko00000 - - - MalM k141_31286_7 1116375.VEJY3_23771 3.82e-58 186.0 COG0366@1|root,COG0366@2|Bacteria,1QJND@1224|Proteobacteria,1THP3@1236|Gammaproteobacteria,1XWZW@135623|Vibrionales 135623|Vibrionales M Alpha amylase catalytic - - - - - - - - - - - - - k141_19417_2 666686.B1NLA3E_02255 3.57e-53 171.0 COG0780@1|root,COG0780@2|Bacteria,1TPYC@1239|Firmicutes,4HB14@91061|Bacilli,1ZB8C@1386|Bacillus 91061|Bacilli S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) queF - 1.7.1.13 ko:K09457 ko00790,ko01100,map00790,map01100 - R07605 RC01875 ko00000,ko00001,ko01000,ko03016 - - - QueF k141_8774_1 1294265.JCM21738_2736 8.63e-109 315.0 COG1845@1|root,COG1845@2|Bacteria,1TQJ1@1239|Firmicutes,4HAHK@91061|Bacilli,1ZBVD@1386|Bacillus 91061|Bacilli C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3 ctaE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.9.3.1 ko:K02276 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.4,3.D.4.6 - - COX3 k141_12404_2 223926.28806520 4.83e-94 283.0 COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,1RNPX@1236|Gammaproteobacteria,1XT3F@135623|Vibrionales 135623|Vibrionales P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system potA GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015203,GO:0015399,GO:0015405,GO:0015417,GO:0015695,GO:0015696,GO:0015846,GO:0015847,GO:0015848,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:1902047 3.6.3.31 ko:K11072 ko02010,map02010 M00299 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.11.1 - - ABC_tran,TOBE_2 k141_6448_2 573370.DMR_19710 9.16e-29 118.0 COG2370@1|root,COG2370@2|Bacteria,1MV6Z@1224|Proteobacteria,42VYC@68525|delta/epsilon subdivisions,2WREK@28221|Deltaproteobacteria,2MFJS@213115|Desulfovibrionales 28221|Deltaproteobacteria O HupE / UreJ protein - - - - - - - - - - - - HupE_UreJ_2 k141_33709_1 1453501.JELR01000002_gene1393 8.24e-170 481.0 COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,1RQJ9@1236|Gammaproteobacteria,466HH@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K03585 ko01501,ko01503,map01501,map01503 M00646,M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,8.A.1.6 - - HlyD_D23 k141_4050_1 743719.PaelaDRAFT_1894 7.44e-46 154.0 2DNQ8@1|root,32YJ3@2|Bacteria,1U9P7@1239|Firmicutes,4IJV6@91061|Bacilli,272YU@186822|Paenibacillaceae 91061|Bacilli - - - - - - - - - - - - - - - k141_25383_1 218284.CCDN010000001_gene1070 3.73e-133 390.0 COG4955@1|root,COG4955@2|Bacteria,1TQU9@1239|Firmicutes,4HFUR@91061|Bacilli,1ZDGR@1386|Bacillus 91061|Bacilli S protein conserved in bacteria ypbB - 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 - - - HTH_40,RQC k141_25383_2 218284.CCDN010000001_gene1071 2.05e-166 479.0 COG0514@1|root,COG0514@2|Bacteria,1TPN5@1239|Firmicutes,4H9QP@91061|Bacilli,1ZB1X@1386|Bacillus 91061|Bacilli L DNA helicase recQ GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009378,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.6.4.12 ko:K03654 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecQ_Zn_bind k141_30018_1 665952.HMPREF1015_00617 7.44e-85 256.0 COG0692@1|root,COG0692@2|Bacteria,1TPSN@1239|Firmicutes,4HBTR@91061|Bacilli,1ZBCY@1386|Bacillus 91061|Bacilli L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine ung GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360 3.2.2.27 ko:K03648 ko03410,ko05340,map03410,map05340 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG k141_35972_1 218284.CCDN010000001_gene1941 6.85e-194 546.0 COG2252@1|root,COG2252@2|Bacteria,1TQC6@1239|Firmicutes,4HANG@91061|Bacilli,1ZDJJ@1386|Bacillus 91061|Bacilli S permease pbuO - - ko:K06901 - - - - ko00000,ko02000 2.A.1.40 - - Xan_ur_permease k141_14624_1 292459.STH2254 9.5e-08 57.4 COG0842@1|root,COG0842@2|Bacteria 2|Bacteria V Transport permease protein - - - ko:K01990,ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane,ABC2_membrane_3 k141_25384_2 1192124.LIG30_2412 1.04e-09 59.3 COG1801@1|root,COG1801@2|Bacteria,1MXIQ@1224|Proteobacteria,2VJWC@28216|Betaproteobacteria,1JZY5@119060|Burkholderiaceae 28216|Betaproteobacteria S Protein of unknown function DUF72 - - - - - - - - - - - - DUF72 k141_15840_1 393595.ABO_2196 4.57e-78 249.0 COG3211@1|root,COG3211@2|Bacteria,1MU8T@1224|Proteobacteria,1RSM7@1236|Gammaproteobacteria,1XN64@135619|Oceanospirillales 135619|Oceanospirillales S Bacterial protein of unknown function (DUF839) - - - ko:K07093 - - - - ko00000 - - - DUF839 k141_13596_1 1385514.N782_20630 8.18e-75 234.0 COG1226@1|root,COG1226@2|Bacteria,1TT0B@1239|Firmicutes,4HBDX@91061|Bacilli,2Y99C@289201|Pontibacillus 91061|Bacilli U Ion transporter kch - - ko:K10716 - - - - ko00000,ko02000 1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6 - - Ion_trans_2,TrkA_N k141_17038_1 218284.CCDN010000001_gene1117 8.22e-145 415.0 COG0079@1|root,COG0079@2|Bacteria,1TPUV@1239|Firmicutes,4HA1H@91061|Bacilli,1ZBYJ@1386|Bacillus 91061|Bacilli E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily hisC - 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k141_17038_2 218284.CCDN010000001_gene1116 1.38e-52 167.0 COG4401@1|root,COG4401@2|Bacteria,1VAID@1239|Firmicutes,4HKTN@91061|Bacilli,1ZH0S@1386|Bacillus 91061|Bacilli E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis aroH GO:0003674,GO:0003824,GO:0004106,GO:0006082,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044281,GO:0046417,GO:0071704 5.4.99.5 ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024,M00025 R01715 RC03116 ko00000,ko00001,ko00002,ko01000 - - - CM_1 k141_5151_1 1294265.JCM21738_153 1.35e-125 362.0 COG2333@1|root,COG2333@2|Bacteria,1VI9A@1239|Firmicutes,4HIJR@91061|Bacilli,1ZES1@1386|Bacillus 91061|Bacilli S competence protein COMEC - - - - - - - - - - - - Lactamase_B k141_5151_2 1294265.JCM21738_154 4.17e-30 107.0 2E85E@1|root,332IZ@2|Bacteria,1VHMN@1239|Firmicutes,4HPYR@91061|Bacilli,1ZIUT@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF4264) ypmA - - - - - - - - - - - DUF4264 k141_20548_1 218284.CCDN010000002_gene2748 2.63e-122 359.0 COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,4H9M0@91061|Bacilli,1ZEIA@1386|Bacillus 91061|Bacilli J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family - - 2.1.1.190 ko:K03215 - - - - ko00000,ko01000,ko03009 - - - tRNA_U5-meth_tr k141_23061_1 218284.CCDN010000001_gene627 8.11e-75 228.0 COG2891@1|root,COG2891@2|Bacteria,1VEN7@1239|Firmicutes,4HNWW@91061|Bacilli,1ZGID@1386|Bacillus 91061|Bacilli M shape-determining protein mreD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03571 - - - - ko00000,ko03036 9.B.157.1 - - MreD k141_23061_2 218284.CCDN010000001_gene626 3.56e-109 321.0 COG1792@1|root,COG1792@2|Bacteria,1TR1V@1239|Firmicutes,4HB0K@91061|Bacilli,1ZC8X@1386|Bacillus 91061|Bacilli M Involved in formation and maintenance of cell shape mreC GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0022603,GO:0022604,GO:0030428,GO:0042546,GO:0043621,GO:0044085,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944 - ko:K03570 - - - - ko00000,ko03036 9.B.157.1 - - MreC k141_23062_1 314265.R2601_17764 6.88e-82 261.0 COG2885@1|root,COG2885@2|Bacteria,1MWHF@1224|Proteobacteria,2TUGX@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Belongs to the ompA family - - - ko:K03286 - - - - ko00000,ko02000 1.B.6 - - BON,OmpA k141_8777_1 1294265.JCM21738_4687 1.87e-143 420.0 COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HB1B@91061|Bacilli,1ZC0T@1386|Bacillus 91061|Bacilli T Signal transduction histidine kinase phoR - 2.7.13.3 ko:K07636 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_9,sCache_like k141_508_2 379066.GAU_1492 1.14e-181 536.0 COG0542@1|root,COG0542@2|Bacteria,1ZT9Z@142182|Gemmatimonadetes 142182|Gemmatimonadetes O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE clpB - - ko:K03695 ko04213,map04213 - - - ko00000,ko00001,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N k141_32384_1 218284.CCDN010000007_gene4009 2.06e-40 134.0 COG4836@1|root,COG4836@2|Bacteria,1VK5C@1239|Firmicutes,4HR8D@91061|Bacilli,1ZJ1E@1386|Bacillus 91061|Bacilli S membrane ywzB - - - - - - - - - - - DUF1146 k141_20549_1 1042377.AFPJ01000055_gene959 1.09e-64 222.0 COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,1RPAG@1236|Gammaproteobacteria,465SE@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Non-ribosomal peptide synthetase - - - - - - - - - - - - AMP-binding,AMP-binding_C,Acyl_transf_1,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_12,PP-binding,Thioesterase,ketoacyl-synt k141_5153_1 399739.Pmen_4556 2.14e-101 321.0 COG4773@1|root,COG4773@2|Bacteria,1MW5E@1224|Proteobacteria,1RMBD@1236|Gammaproteobacteria 1236|Gammaproteobacteria P receptor fhuE - - ko:K16088 - - - - ko00000,ko02000 1.B.14.1.10,1.B.14.1.3,1.B.14.1.8 - - Plug,TonB_dep_Rec k141_19418_1 945550.VISI1226_09569 6.55e-178 496.0 COG0834@1|root,COG0834@2|Bacteria,1MWDK@1224|Proteobacteria,1RZ89@1236|Gammaproteobacteria,1Y248@135623|Vibrionales 135623|Vibrionales ET Ligated ion channel L-glutamate- and glycine-binding site - - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 k141_13600_1 240302.BN982_01031 7.26e-77 239.0 COG0730@1|root,COG0730@2|Bacteria,1TT6E@1239|Firmicutes,4HC1R@91061|Bacilli 91061|Bacilli S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE k141_33711_1 155515.JP36_04750 7.68e-06 47.8 COG2274@1|root,COG2274@2|Bacteria,1R2T0@1224|Proteobacteria,1SBE1@1236|Gammaproteobacteria,1Y81Y@135625|Pasteurellales 135625|Pasteurellales V ABC transporter transmembrane region - - - ko:K12541 ko02010,map02010 M00330 - - ko00000,ko00001,ko00002,ko02000,ko02044 3.A.1.109.3,3.A.1.109.4 - - ABC_membrane,ABC_tran k141_33711_2 1042377.AFPJ01000042_gene1095 1.69e-201 570.0 COG0845@1|root,COG0845@2|Bacteria,1MUI8@1224|Proteobacteria,1RNK4@1236|Gammaproteobacteria,464KG@72275|Alteromonadaceae 1236|Gammaproteobacteria M Secretion protein - - - ko:K12542 - M00330 - - ko00000,ko00002,ko02000,ko02044 3.A.1.109.4,8.A.1 - - Biotin_lipoyl_2,HlyD,HlyD_3 k141_37373_37 1279017.AQYJ01000026_gene289 6.33e-129 368.0 COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,1RN64@1236|Gammaproteobacteria,465S4@72275|Alteromonadaceae 1236|Gammaproteobacteria K Belongs to the sigma-70 factor family. ECF subfamily rpoE GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0006950,GO:0006970,GO:0008150,GO:0009266,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_37373_38 1042377.AFPJ01000037_gene2864 0.0 956.0 COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,1RMMD@1236|Gammaproteobacteria,464BS@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the oxidation of L-aspartate to iminoaspartate nadB GO:0000166,GO:0001716,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008734,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0015922,GO:0016491,GO:0016638,GO:0016641,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044318,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.4.3.16 ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 M00115 R00357,R00481 RC00006,RC02566 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b2574,iBWG_1329.BWG_2338,iECDH10B_1368.ECDH10B_2742,iECDH1ME8569_1439.ECDH1ME8569_2501,iETEC_1333.ETEC_2787,iEcDH1_1363.EcDH1_1094,iJO1366.b2574,iJR904.b2574,iLF82_1304.LF82_1433,iNRG857_1313.NRG857_12785,iY75_1357.Y75_RS13445,iYL1228.KPN_02899 FAD_binding_2,Succ_DH_flav_C k141_37373_40 1279017.AQYJ01000026_gene292 4.06e-46 149.0 COG2938@1|root,COG2938@2|Bacteria,1N7P4@1224|Proteobacteria,1SCKB@1236|Gammaproteobacteria,468IZ@72275|Alteromonadaceae 1236|Gammaproteobacteria S Flavinator of succinate dehydrogenase ygfY GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006105,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016043,GO:0016999,GO:0017013,GO:0017144,GO:0018065,GO:0018293,GO:0019538,GO:0019752,GO:0022607,GO:0034552,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0043648,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0045333,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072350,GO:1901564 - ko:K09159 - - - - ko00000,ko02048 - - - Sdh5 k141_37373_41 1279017.AQYJ01000026_gene293 5.77e-135 395.0 COG0354@1|root,COG0354@2|Bacteria,1N852@1224|Proteobacteria,1RPWB@1236|Gammaproteobacteria,466QJ@72275|Alteromonadaceae 1236|Gammaproteobacteria S aminomethyltransferase related to GcvT ygfZ GO:0003674,GO:0005488,GO:0005542,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0019842,GO:0022607,GO:0031163,GO:0031406,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0071840,GO:0072341,GO:0097159,GO:1901363 - ko:K06980 - - - - ko00000,ko03016 - - - GCV_T,GCV_T_C k141_37373_42 1279017.AQYJ01000026_gene294 1.4e-152 431.0 COG0692@1|root,COG0692@2|Bacteria,1MV80@1224|Proteobacteria,1RPDH@1236|Gammaproteobacteria,4650X@72275|Alteromonadaceae 1236|Gammaproteobacteria L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine ung GO:0003674,GO:0003824,GO:0004844,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360 3.2.2.27 ko:K03648 ko03410,ko05340,map03410,map05340 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG k141_37373_43 1279017.AQYJ01000026_gene295 1.04e-119 343.0 COG1573@1|root,COG1573@2|Bacteria,1R9XV@1224|Proteobacteria,1S20R@1236|Gammaproteobacteria,4671B@72275|Alteromonadaceae 1236|Gammaproteobacteria L Uracil-DNA glycosylase - - - - - - - - - - - - UDG k141_37373_44 1042377.AFPJ01000037_gene2870 7.24e-105 317.0 COG4222@1|root,COG4222@2|Bacteria,1NRU1@1224|Proteobacteria,1SM0C@1236|Gammaproteobacteria 1236|Gammaproteobacteria S DNA topoisomerase IV subunit B - - - - - - - - - - - - Phytase-like k141_37373_45 1279017.AQYJ01000026_gene299 5.47e-88 261.0 COG1666@1|root,COG1666@2|Bacteria,1RDTF@1224|Proteobacteria,1S3RU@1236|Gammaproteobacteria,466ZE@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the UPF0234 family yajQ GO:0000049,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0009987,GO:0017076,GO:0019001,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033554,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K09767 - - - - ko00000 - - - DUF520 k141_37373_46 1279017.AQYJ01000026_gene300 3.75e-90 268.0 COG4681@1|root,COG4681@2|Bacteria,1RDR9@1224|Proteobacteria,1S43N@1236|Gammaproteobacteria,466WM@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria yaeQ - - - - - - - - - - - YaeQ k141_37373_47 1504981.KO116_2260 2.89e-96 286.0 COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,1RS3E@1236|Gammaproteobacteria,1XP29@135619|Oceanospirillales 135619|Oceanospirillales S LemA family - - - ko:K03744 - - - - ko00000 - - - LemA k141_37373_48 1042377.AFPJ01000037_gene2874 1.87e-99 297.0 COG1512@1|root,COG1512@2|Bacteria,1PB41@1224|Proteobacteria,1S38U@1236|Gammaproteobacteria,466VG@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG1512 Beta-propeller domains of methanol dehydrogenase type Z012_08980 - - ko:K06872 - - - - ko00000 - - - TPM_phosphatase k141_37373_49 1042377.AFPJ01000037_gene2875 1.13e-110 322.0 COG3762@1|root,COG3762@2|Bacteria,1R61N@1224|Proteobacteria,1S2RR@1236|Gammaproteobacteria,466UH@72275|Alteromonadaceae 1236|Gammaproteobacteria S Membrane - - - ko:K08988 - - - - ko00000 - - - TPM_phosphatase k141_37373_50 1042377.AFPJ01000037_gene2876 1.72e-58 195.0 28RR1@1|root,2ZE3K@2|Bacteria,1P7PJ@1224|Proteobacteria,1SUUS@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain present in PSD-95, Dlg, and ZO-1/2. - - - - - - - - - - - - PDZ_2 k141_37373_51 1116369.KB890024_gene3986 0.000757 49.3 COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2TQPZ@28211|Alphaproteobacteria,43MVH@69277|Phyllobacteriaceae 28211|Alphaproteobacteria O Belongs to the peptidase S1C family degPch1 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Trypsin_2 k141_37373_52 1453501.JELR01000001_gene1965 0.0 895.0 COG1190@1|root,COG1190@2|Bacteria,1MX1V@1224|Proteobacteria,1RMJN@1236|Gammaproteobacteria,465T6@72275|Alteromonadaceae 1236|Gammaproteobacteria J Belongs to the class-II aminoacyl-tRNA synthetase family lysS GO:0003674,GO:0003824,GO:0004812,GO:0004824,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006430,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.6 ko:K04567 ko00970,map00970 M00359,M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2,tRNA_anti-codon k141_37373_53 1279017.AQYJ01000026_gene310 1.66e-187 523.0 COG1186@1|root,COG1186@2|Bacteria,1MUAW@1224|Proteobacteria,1RP9Z@1236|Gammaproteobacteria,464MX@72275|Alteromonadaceae 1236|Gammaproteobacteria J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA prfB GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02836 - - - - ko00000,ko03012 - - - PCRF,RF-1 k141_37373_54 1279017.AQYJ01000026_gene312 3.02e-36 129.0 2EH9Y@1|root,33B1U@2|Bacteria,1NIC9@1224|Proteobacteria,1SHT9@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_37373_56 1453501.JELR01000001_gene1959 3.66e-154 439.0 COG0697@1|root,COG0697@2|Bacteria,1N024@1224|Proteobacteria,1S1KP@1236|Gammaproteobacteria,46DI4@72275|Alteromonadaceae 1236|Gammaproteobacteria EG EamA-like transporter family - - - - - - - - - - - - EamA k141_37373_57 1279017.AQYJ01000026_gene315 0.0 935.0 COG0608@1|root,COG0608@2|Bacteria,1MU1M@1224|Proteobacteria,1RMF4@1236|Gammaproteobacteria,46499@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG0608 Single-stranded DNA-specific exonuclease recJ GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008297,GO:0008409,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0035312,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0045145,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1 k141_37373_58 1279017.AQYJ01000026_gene316 4.4e-284 782.0 COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,1RQ0H@1236|Gammaproteobacteria,463ZB@72275|Alteromonadaceae 1236|Gammaproteobacteria E Threonine synthase thrC GO:0003674,GO:0003824,GO:0004795,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 - - iLF82_1304.LF82_2261,iNRG857_1313.NRG857_00025 PALP,Thr_synth_N k141_37373_59 1279017.AQYJ01000026_gene317 1.63e-243 677.0 COG0460@1|root,COG0460@2|Bacteria,1MUDC@1224|Proteobacteria,1RPEU@1236|Gammaproteobacteria,463Y5@72275|Alteromonadaceae 1236|Gammaproteobacteria E homoserine dehydrogenase hom - 1.1.1.3,2.7.2.4 ko:K00003,ko:K12524 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00017,M00018,M00526,M00527 R00480,R01773,R01775 RC00002,RC00043,RC00087 ko00000,ko00001,ko00002,ko01000 - - - ACT,Homoserine_dh,NAD_binding_3 k141_13933_1 95619.PM1_0205205 3.19e-89 280.0 COG4690@1|root,COG4690@2|Bacteria,1RBRZ@1224|Proteobacteria,1SKSZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Peptidase family C69 - - - - - - - - - - - - Peptidase_C69 k141_13933_2 1117647.M5M_13340 4.21e-156 455.0 COG1231@1|root,COG1231@2|Bacteria,1P3D9@1224|Proteobacteria,1S0H2@1236|Gammaproteobacteria,1JA3E@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Flavin containing amine oxidoreductase - - 1.4.3.4 ko:K00274 ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034 M00135 R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354 RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713 ko00000,ko00001,ko00002,ko01000 - - - Amino_oxidase k141_11456_1 1294265.JCM21738_2252 1.57e-118 341.0 COG0624@1|root,COG0624@2|Bacteria,1TPEG@1239|Firmicutes,4HC14@91061|Bacilli,1ZBI2@1386|Bacillus 91061|Bacilli E Dipeptidase ytjP - 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20 k141_19721_1 42565.FP66_02575 5.89e-234 656.0 COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,1RMM1@1236|Gammaproteobacteria,1XHS4@135619|Oceanospirillales 135619|Oceanospirillales D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 gidA - - ko:K03495 - - R08701 RC00053,RC00209,RC00870 ko00000,ko03016,ko03036 - - - GIDA,GIDA_assoc k141_27814_2 1279017.AQYJ01000021_gene2873 1.09e-49 160.0 COG3784@1|root,COG3784@2|Bacteria,1N6R1@1224|Proteobacteria,1SC8V@1236|Gammaproteobacteria,4694V@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF1318) ydbL - - ko:K09978 - - - - ko00000 - - - DUF1318 k141_35170_1 545693.BMQ_1216 1.7e-88 269.0 COG0225@1|root,COG0229@1|root,COG0225@2|Bacteria,COG0229@2|Bacteria,1TQ3E@1239|Firmicutes,4HAIV@91061|Bacilli,1ZCC5@1386|Bacillus 91061|Bacilli O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine msrB - 1.8.4.11,1.8.4.12 ko:K07304,ko:K12267 - - - - ko00000,ko01000 - - - PMSR,SelR k141_27033_1 1294265.JCM21738_2205 7.14e-49 156.0 2AYX9@1|root,31R2Z@2|Bacteria,1V1KP@1239|Firmicutes,4HFV5@91061|Bacilli,1ZFIN@1386|Bacillus 91061|Bacilli S DinB superfamily - - - - - - - - - - - - DinB_2 k141_27033_2 1294265.JCM21738_2204 6.89e-29 107.0 2AQ7Q@1|root,31FDF@2|Bacteria,1UA0M@1239|Firmicutes,4IK97@91061|Bacilli,1ZG00@1386|Bacillus 91061|Bacilli S DnaJ molecular chaperone homology domain - - - - - - - - - - - - - k141_11457_1 768066.HELO_3431 2.51e-41 135.0 COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,1XM5A@135619|Oceanospirillales 135619|Oceanospirillales K cold-shock protein cspG - - ko:K03704 - - - - ko00000,ko03000 - - - CSD k141_14833_1 1294265.JCM21738_4405 3.25e-90 271.0 COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,4H9ZW@91061|Bacilli,1ZB08@1386|Bacillus 91061|Bacilli S COG0618 Exopolyphosphatase-related proteins nrnA - 3.1.13.3,3.1.3.7 ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 - R00188,R00508 RC00078 ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1 k141_37374_1 218284.CCDN010000001_gene1066 4.49e-27 108.0 2E6XT@1|root,331H4@2|Bacteria,1VJ9Y@1239|Firmicutes,4HPEM@91061|Bacilli,1ZBUX@1386|Bacillus 91061|Bacilli - - rsiX GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - Germane k141_37374_2 218284.CCDN010000001_gene1067 7.72e-20 87.4 COG0739@1|root,COG0739@2|Bacteria,1V3ZU@1239|Firmicutes,4I27X@91061|Bacilli,1ZGNS@1386|Bacillus 91061|Bacilli M COG0739 Membrane proteins related to metalloendopeptidases - - - - - - - - - - - - LysM,Peptidase_M23 k141_19722_1 935836.JAEL01000015_gene202 3.22e-88 275.0 COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HACS@91061|Bacilli,1ZATG@1386|Bacillus 91061|Bacilli IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - ko:K00666 - - - - ko00000,ko01000,ko01004 - - - AMP-binding,AMP-binding_C k141_20764_1 1280001.BAOA01000009_gene4139 5.54e-61 199.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RNGU@1236|Gammaproteobacteria,1XSJ5@135623|Vibrionales 135623|Vibrionales I Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed fadI GO:0003674,GO:0003824,GO:0003988,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 2.3.1.16 ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 M00087,M00113 R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095 RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955 ko00000,ko00001,ko00002,ko01000 - - - Thiolase_C,Thiolase_N k141_20764_2 1116375.VEJY3_11385 7.96e-125 356.0 COG1595@1|root,COG1595@2|Bacteria,1R9ZN@1224|Proteobacteria,1S7BJ@1236|Gammaproteobacteria,1XTMQ@135623|Vibrionales 135623|Vibrionales K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_20764_3 1116375.VEJY3_11390 1.26e-140 400.0 COG5662@1|root,COG5662@2|Bacteria,1RJ4M@1224|Proteobacteria,1S23M@1236|Gammaproteobacteria,1XURI@135623|Vibrionales 135623|Vibrionales K Protein of unknown function (DUF3379) EBIG1770 - - - - - - - - - - - DUF3379 k141_20764_4 55601.VANGNB10_cI0919c 5.08e-247 685.0 COG2067@1|root,COG2067@2|Bacteria,1NM5K@1224|Proteobacteria,1SKF5@1236|Gammaproteobacteria,1XSQN@135623|Vibrionales 135623|Vibrionales I long-chain fatty acid transport protein fadL - - ko:K06076 - - - - ko00000,ko02000 1.B.9 - - Toluene_X k141_20764_5 223926.28807206 8.6e-179 508.0 COG2067@1|root,COG2067@2|Bacteria,1MUU4@1224|Proteobacteria,1RQZJ@1236|Gammaproteobacteria,1XSHP@135623|Vibrionales 135623|Vibrionales I Long-chain fatty acid transport protein - - - ko:K06076 - - - - ko00000,ko02000 1.B.9 - - Toluene_X k141_2936_2 595494.Tola_2899 0.0 1634.0 COG0439@1|root,COG1984@1|root,COG2049@1|root,COG0439@2|Bacteria,COG1984@2|Bacteria,COG2049@2|Bacteria,1MU4H@1224|Proteobacteria,1T1GN@1236|Gammaproteobacteria,1Y6PD@135624|Aeromonadales 135624|Aeromonadales EI Allophanate hydrolase subunit 2 - - 6.3.4.6 ko:K01941 ko00220,ko00791,ko01100,map00220,map00791,map01100 - R00774 RC00378 ko00000,ko00001,ko01000 - - - Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,CT_A_B,CT_C_D k141_2936_3 1120970.AUBZ01000005_gene424 1.98e-125 360.0 COG3665@1|root,COG3665@2|Bacteria,1N9DM@1224|Proteobacteria,1RR1E@1236|Gammaproteobacteria,464DR@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF1989) ycgI - - ko:K09967 - - - - ko00000 - - - DUF1989 k141_2936_4 393595.ABO_1890 1.74e-17 79.7 COG3665@1|root,COG3665@2|Bacteria,1N2KR@1224|Proteobacteria,1RN5H@1236|Gammaproteobacteria,1XIHT@135619|Oceanospirillales 135619|Oceanospirillales S Domain of unknown function (DUF1989) - - - ko:K09967 - - - - ko00000 - - - DUF1989 k141_27815_1 1224136.AMFN01000003_gene3181 2.69e-56 191.0 COG0662@1|root,COG0836@1|root,COG0662@2|Bacteria,COG0836@2|Bacteria,1MV39@1224|Proteobacteria,1RNQI@1236|Gammaproteobacteria,2831Q@191675|unclassified Enterobacteriaceae 1236|Gammaproteobacteria M Belongs to the mannose-6-phosphate isomerase type 2 family cpsB GO:0000271,GO:0003674,GO:0003824,GO:0004475,GO:0005975,GO:0005976,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0008152,GO:0008905,GO:0008928,GO:0009058,GO:0009059,GO:0009242,GO:0009628,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016772,GO:0016779,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046377,GO:0050896,GO:0070568,GO:0071704,GO:1901135,GO:1901137,GO:1901576 2.7.7.13,5.3.1.8 ko:K00971,ko:K16011 ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025 M00114,M00361,M00362 R00885,R01819 RC00002,RC00376 ko00000,ko00001,ko00002,ko01000 - - iE2348C_1286.E2348C_2191,iEC042_1314.EC042_2286,iECIAI1_1343.ECIAI1_2124,iECO26_1355.ECO26_2960,iECSE_1348.ECSE_2323,iECW_1372.ECW_m2206,iEKO11_1354.EKO11_1746,iEcE24377_1341.EcE24377A_2342,iLF82_1304.LF82_0345,iNRG857_1313.NRG857_10420,iWFL_1372.ECW_m2206 MannoseP_isomer,NTP_transferase k141_32603_1 218284.CCDN010000009_gene4321 5.03e-246 682.0 COG3547@1|root,COG3547@2|Bacteria,1TQ5G@1239|Firmicutes,4HB35@91061|Bacilli,1ZCUW@1386|Bacillus 91061|Bacilli L COG3547 Transposase and inactivated derivatives - - - ko:K07486 - - - - ko00000 - - - DEDD_Tnp_IS110,Transposase_20 k141_35171_1 1423321.AS29_19370 5.29e-19 79.7 2EIS2@1|root,33CHE@2|Bacteria 2|Bacteria S Inhibitor of sigma-G Gin csfB - - - - - - - - - - - Gin k141_27034_1 218284.CCDN010000001_gene1281 7.06e-125 368.0 COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,4HB31@91061|Bacilli,1ZARE@1386|Bacillus 91061|Bacilli EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia trpE GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.1.3.27 ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Anth_synt_I_N,Chorismate_bind k141_27034_2 536227.CcarbDRAFT_4315 5.95e-28 106.0 COG0512@1|root,COG0512@2|Bacteria,1TT9R@1239|Firmicutes,24FR0@186801|Clostridia,36I54@31979|Clostridiaceae 186801|Clostridia EH Glutamine amidotransferase of anthranilate synthase trpG - 4.1.3.27 ko:K01658 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - GATase k141_12726_1 1122927.KB895414_gene5233 4.22e-20 90.5 COG0673@1|root,COG0673@2|Bacteria,1TPT5@1239|Firmicutes,4HAPJ@91061|Bacilli,26TP1@186822|Paenibacillaceae 91061|Bacilli S Oxidoreductase - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C k141_12726_2 1293054.HSACCH_01185 2.88e-24 100.0 COG0821@1|root,COG0821@2|Bacteria,1TPFR@1239|Firmicutes,247N1@186801|Clostridia,3WAH4@53433|Halanaerobiales 186801|Clostridia I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate ispG - 1.17.7.1,1.17.7.3 ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R08689,R10859 RC01486 ko00000,ko00001,ko00002,ko01000 - - iHN637.CLJU_RS06430 GcpE k141_31402_1 218284.CCDN010000002_gene2029 3.7e-63 195.0 COG5012@1|root,COG5012@2|Bacteria,1UIKM@1239|Firmicutes,4ISMI@91061|Bacilli,1ZS6Q@1386|Bacillus 91061|Bacilli S cobalamin binding - - - - - - - - - - - - - k141_27035_1 218284.CCDN010000001_gene46 2.66e-137 410.0 COG1198@1|root,COG1198@2|Bacteria,1TNYB@1239|Firmicutes,4H9WW@91061|Bacilli,1ZCBY@1386|Bacillus 91061|Bacilli L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA priA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - ko:K04066 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,ResIII k141_18597_1 565045.NOR51B_2623 2.51e-15 75.9 COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,1RNQS@1236|Gammaproteobacteria,1J4C0@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria K Participates in both transcription termination and antitermination nusA GO:0001000,GO:0001121,GO:0001125,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0019904,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043175,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - ko:K02600 - - - - ko00000,ko03009,ko03021 - - - HHH_5,KH_5,NusA_N,S1 k141_18597_2 596320.NEIFL0001_1617 4.64e-05 47.8 COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,2VK2H@28216|Betaproteobacteria,2KPC4@206351|Neisseriales 206351|Neisseriales J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB - - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,IF-2,IF2_N,IF2_assoc k141_19724_1 42565.FP66_15065 5.07e-150 434.0 COG0404@1|root,COG0404@2|Bacteria,1QV5I@1224|Proteobacteria,1SK44@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Glycine cleavage T-protein C-terminal barrel domain - - - - - - - - - - - - DAO,FAO_M,GCV_T,GCV_T_C k141_29116_1 218284.CCDN010000001_gene733 9.29e-73 224.0 COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,4HIRK@91061|Bacilli,1ZGCW@1386|Bacillus 91061|Bacilli O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ grpE GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 - ko:K03687 - - - - ko00000,ko03029,ko03110 - - - GrpE k141_11460_1 1219065.VPR01S_18_00800 2.37e-145 444.0 COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,1RMRN@1236|Gammaproteobacteria,1XTXA@135623|Vibrionales 135623|Vibrionales F Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate purL GO:0003674,GO:0003824,GO:0004642,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - AIRS_C,GATase_5 k141_17260_1 1042377.AFPJ01000007_gene1869 2.03e-36 134.0 COG5621@1|root,COG5621@2|Bacteria,1MUVF@1224|Proteobacteria,1RZ65@1236|Gammaproteobacteria,466MJ@72275|Alteromonadaceae 1236|Gammaproteobacteria S secreted hydrolase attH - - - - - - - - - - - CrtC,Lipocalin_9 k141_17260_2 1042377.AFPJ01000007_gene1870 1.83e-204 592.0 COG3127@1|root,COG3127@2|Bacteria,1QXGA@1224|Proteobacteria,1T3BG@1236|Gammaproteobacteria,467CX@72275|Alteromonadaceae 1236|Gammaproteobacteria Q COG0577 ABC-type antimicrobial peptide transport system, permease component - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX k141_32605_1 1294265.JCM21738_4210 1.51e-69 219.0 COG0609@1|root,COG0609@2|Bacteria,1TPX6@1239|Firmicutes,4HAM8@91061|Bacilli,1ZAU0@1386|Bacillus 91061|Bacilli P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily yfhA - - ko:K02015 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - FecCD k141_32605_2 1294265.JCM21738_4211 7.98e-24 96.3 COG1120@1|root,COG1120@2|Bacteria,1TP2Q@1239|Firmicutes,4HADG@91061|Bacilli,1ZBMI@1386|Bacillus 91061|Bacilli HP ABC transporter yusV - 3.6.3.34 ko:K02013 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 - - ABC_tran k141_27817_1 218284.CCDN010000007_gene3787 9e-117 351.0 COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,4H9Y6@91061|Bacilli,1ZBFI@1386|Bacillus 91061|Bacilli L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrB GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.3 ko:K02470 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim k141_24414_1 1279017.AQYJ01000024_gene924 1.45e-48 157.0 COG2921@1|root,COG2921@2|Bacteria,1PJDV@1224|Proteobacteria,1SXYT@1236|Gammaproteobacteria,468E1@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the UPF0250 family - - - ko:K09158 - - - - ko00000 - - - DUF493 k141_14835_1 1453501.JELR01000005_gene1750 2.03e-84 256.0 COG1540@1|root,COG1540@2|Bacteria,1MUYV@1224|Proteobacteria,1RSCZ@1236|Gammaproteobacteria,4659M@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the UPF0271 (lamB) family ybgL - - ko:K07160 - - - - ko00000 - - - LamB_YcsF k141_30210_1 218284.CCDN010000006_gene3533 2.27e-120 361.0 COG1075@1|root,COG1075@2|Bacteria,1TQFF@1239|Firmicutes,4HDQN@91061|Bacilli,1ZCCU@1386|Bacillus 91061|Bacilli S acetyltransferases and hydrolases with the alpha beta hydrolase fold lipA1 - - - - - - - - - - - DUF676,PGAP1 k141_17261_1 1279017.AQYJ01000028_gene2268 6.06e-59 205.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MWTT@1224|Proteobacteria,1RP0H@1236|Gammaproteobacteria,46CKB@72275|Alteromonadaceae 1236|Gammaproteobacteria P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec k141_27037_1 796606.BMMGA3_03475 7.77e-96 289.0 COG4129@1|root,COG4129@2|Bacteria,1TPVH@1239|Firmicutes,4HAEG@91061|Bacilli,1ZCJA@1386|Bacillus 91061|Bacilli S Membrane ygaE - - - - - - - - - - - ArAE_1 k141_36191_2 1042377.AFPJ01000028_gene2274 1.21e-20 87.8 COG1495@1|root,COG1495@2|Bacteria,1RKPG@1224|Proteobacteria,1SC4J@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Disulfide bond formation protein DsbB lidJ - - - - - - - - - - - DsbB k141_11462_1 218284.CCDN010000001_gene647 8.1e-62 195.0 2C7CE@1|root,30872@2|Bacteria,1V67M@1239|Firmicutes,4HHGE@91061|Bacilli,1ZDZH@1386|Bacillus 91061|Bacilli S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) - - - ko:K06345 - - - - ko00000 - - - Spore_YhcN_YlaJ k141_5551_1 42256.RradSPS_1175 3.41e-29 114.0 COG5039@1|root,COG5039@2|Bacteria 2|Bacteria GM polysaccharide biosynthetic process - - - - - - - - - - - - PS_pyruv_trans k141_5551_2 1196028.ALEF01000015_gene2573 4.54e-71 223.0 COG1215@1|root,COG1215@2|Bacteria,1V4HY@1239|Firmicutes,4HHVA@91061|Bacilli 91061|Bacilli M COG0463, glycosyltransferases involved in cell wall biogenesis - - - - - - - - - - - - Glyco_transf_7C,Glycos_transf_2 k141_7709_1 1295642.H839_13974 5.83e-84 254.0 COG1215@1|root,COG1215@2|Bacteria,1TPBB@1239|Firmicutes,4HBVS@91061|Bacilli,1WEVU@129337|Geobacillus 91061|Bacilli M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 k141_23372_1 1453501.JELR01000001_gene1960 3.25e-119 343.0 COG1280@1|root,COG1280@2|Bacteria,1Q4CV@1224|Proteobacteria,1RQV8@1236|Gammaproteobacteria,466TI@72275|Alteromonadaceae 1236|Gammaproteobacteria E Lysine exporter protein (LysE YggA) - - - ko:K05834 - - - - ko00000,ko02000 2.A.76.1.1 - - LysE k141_16100_2 1116375.VEJY3_20131 1.4e-169 476.0 COG0765@1|root,COG0765@2|Bacteria,1RBUH@1224|Proteobacteria,1S6RF@1236|Gammaproteobacteria,1XTSX@135623|Vibrionales 135623|Vibrionales P COG0765 ABC-type amino acid transport system, permease component - - - ko:K02029 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 k141_16100_3 1116375.VEJY3_20136 4.05e-177 495.0 COG0834@1|root,COG0834@2|Bacteria,1P22C@1224|Proteobacteria,1RSGY@1236|Gammaproteobacteria,1Y247@135623|Vibrionales 135623|Vibrionales ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain - - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 k141_20788_1 1294265.JCM21738_4815 9.12e-88 260.0 COG2059@1|root,COG2059@2|Bacteria,1V43H@1239|Firmicutes,4HFWH@91061|Bacilli,1ZFJR@1386|Bacillus 91061|Bacilli P COG2059 Chromate transport protein ChrA - - - ko:K07240 - - - - ko00000,ko02000 2.A.51.1 - - Chromate_transp k141_20788_2 933115.GPDM_07610 2.88e-12 63.5 COG2059@1|root,COG2059@2|Bacteria,1V42U@1239|Firmicutes,4HH2P@91061|Bacilli,26EYW@186818|Planococcaceae 91061|Bacilli P Chromate transporter srpC_2 - - ko:K07240 - - - - ko00000,ko02000 2.A.51.1 - - Chromate_transp k141_32640_1 338963.Pcar_1241 1.22e-73 240.0 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,42M5F@68525|delta/epsilon subdivisions,2WJ1T@28221|Deltaproteobacteria,43S9K@69541|Desulfuromonadales 28221|Deltaproteobacteria IQ PFAM AMP-dependent synthetase and ligase - - - ko:K00666 - - - - ko00000,ko01000,ko01004 - - - AMP-binding,AMP-binding_C k141_9059_1 218284.CCDN010000002_gene2801 4.97e-102 296.0 COG0346@1|root,COG0346@2|Bacteria,1UZ2H@1239|Firmicutes,4HEGA@91061|Bacilli,1ZE1A@1386|Bacillus 91061|Bacilli E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - Glyoxalase k141_9059_2 218284.CCDN010000002_gene2800 4.13e-75 224.0 COG1733@1|root,COG1733@2|Bacteria,1VA9M@1239|Firmicutes,4HH0A@91061|Bacilli,1ZH1P@1386|Bacillus 91061|Bacilli K transcriptional hxlR - - - - - - - - - - - HxlR k141_29136_1 1116375.VEJY3_06475 1.75e-176 497.0 COG0614@1|root,COG0614@2|Bacteria,1MUSZ@1224|Proteobacteria,1RPUH@1236|Gammaproteobacteria,1XVTG@135623|Vibrionales 135623|Vibrionales P ABC-type Fe3 -hydroxamate transport system, periplasmic component - - - ko:K02016 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - Peripla_BP_2 k141_29136_2 1191299.AJYX01000065_gene3696 1.48e-36 132.0 COG0609@1|root,COG0609@2|Bacteria,1MV9W@1224|Proteobacteria,1RMST@1236|Gammaproteobacteria,1XSQQ@135623|Vibrionales 135623|Vibrionales P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily - - - ko:K02015 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - FecCD k141_27841_2 1279017.AQYJ01000021_gene2846 2.49e-54 184.0 COG0122@1|root,COG2169@1|root,COG0122@2|Bacteria,COG2169@2|Bacteria,1QTXM@1224|Proteobacteria,1RNQB@1236|Gammaproteobacteria,464XA@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG2169 Adenosine deaminase ada - 3.2.2.21 ko:K01247,ko:K13529 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03000,ko03400 - - - Ada_Zn_binding,AlkA_N,HTH_18,HhH-GPD k141_18634_1 768066.HELO_3960 2.16e-136 395.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RM93@1236|Gammaproteobacteria,1XN9Z@135619|Oceanospirillales 135619|Oceanospirillales I Belongs to the thiolase family - - 2.3.1.174,2.3.1.223,2.3.1.9 ko:K00626,ko:K02615 ko00071,ko00072,ko00280,ko00310,ko00360,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00360,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R00829,R01177,R09839 RC00004,RC00326,RC03003 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N k141_27079_1 218284.CCDN010000002_gene2050 6.02e-57 181.0 COG3859@1|root,COG3859@2|Bacteria,1V6YE@1239|Firmicutes,4HIJE@91061|Bacilli,1ZCR3@1386|Bacillus 91061|Bacilli S Proton-coupled thiamine transporter YuaJ thiT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K16789 - - - - ko00000,ko02000 2.A.88.3 - - Thia_YuaJ k141_27079_2 218284.CCDN010000002_gene2049 2.74e-59 183.0 29T9S@1|root,30EGR@2|Bacteria,1UCIR@1239|Firmicutes,4IP0W@91061|Bacilli,1ZP7W@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_25766_1 314285.KT71_02412 3.25e-79 259.0 COG4772@1|root,COG4772@2|Bacteria,1NTC4@1224|Proteobacteria,1RPFQ@1236|Gammaproteobacteria,1J5XK@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec k141_799_2 1116375.VEJY3_10170 2.21e-202 562.0 COG3637@1|root,COG3637@2|Bacteria,1RHUP@1224|Proteobacteria,1RY1S@1236|Gammaproteobacteria,1Y32A@135623|Vibrionales 135623|Vibrionales M Domain of unknown function (DUF3943) - - - - - - - - - - - - DUF3943,OMP_b-brl k141_799_3 1219076.N646_1021 6.61e-103 299.0 COG2716@1|root,COG2716@2|Bacteria,1NAIN@1224|Proteobacteria,1SEAU@1236|Gammaproteobacteria,1XTJY@135623|Vibrionales 135623|Vibrionales E Glycine cleavage system regulatory protein - - - - - - - - - - - - ACT_6 k141_799_4 223926.28806932 3.2e-271 743.0 COG0019@1|root,COG0019@2|Bacteria,1MW3T@1224|Proteobacteria,1RP8C@1236|Gammaproteobacteria,1XT59@135623|Vibrionales 135623|Vibrionales H Belongs to the Orn Lys Arg decarboxylase class-II family. NspC subfamily nspC GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0019842,GO:0030170,GO:0034641,GO:0036094,GO:0042401,GO:0042710,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0044010,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044764,GO:0045312,GO:0046204,GO:0046983,GO:0048037,GO:0050662,GO:0051704,GO:0070279,GO:0071704,GO:0097159,GO:0097164,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.1.1.96 ko:K13747 ko00330,ko01100,map00330,map01100 - R09081,R09082 RC00299 ko00000,ko00001,ko01000 - - - Orn_DAP_Arg_deC k141_799_5 223926.28806933 2.67e-312 849.0 COG1748@1|root,COG1748@2|Bacteria,1NIU2@1224|Proteobacteria,1RP49@1236|Gammaproteobacteria,1XVG7@135623|Vibrionales 135623|Vibrionales E COG1748 Saccharopine dehydrogenase and related proteins - - 1.5.1.43 ko:K13746 ko00330,ko01100,map00330,map01100 - R09079,R09080 RC00053,RC00225 ko00000,ko00001,ko01000 - - - Sacchrp_dh_C,Sacchrp_dh_NADP k141_799_6 1116375.VEJY3_10190 0.0 1842.0 COG0076@1|root,COG0160@1|root,COG0076@2|Bacteria,COG0160@2|Bacteria,1MWUX@1224|Proteobacteria,1RQ8G@1236|Gammaproteobacteria,1XV42@135623|Vibrionales 135623|Vibrionales E COG0160 4-aminobutyrate aminotransferase and related aminotransferases - - 2.6.1.76,4.1.1.86 ko:K00836,ko:K13745 ko00260,ko01100,ko01120,ko01210,ko01230,map00260,map01100,map01120,map01210,map01230 M00033 R06977,R07650 RC00006,RC00062,RC00299 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3,Pyridoxal_deC k141_23374_1 1382305.AZUC01000057_gene2050 5.66e-34 123.0 COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1URF2@1239|Firmicutes,4HFVG@91061|Bacilli,26GY4@186818|Planococcaceae 91061|Bacilli T helix_turn_helix, arabinose operon control protein - - - ko:K07720 ko02020,map02020 M00519 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_18,HTH_AraC,Response_reg k141_23374_2 1340434.AXVA01000020_gene1435 2.94e-07 52.8 COG2972@1|root,COG2972@2|Bacteria,1V4EZ@1239|Firmicutes,4HH4N@91061|Bacilli,1ZCDD@1386|Bacillus 91061|Bacilli T Histidine kinase - - - - - - - - - - - - His_kinase k141_1959_1 218284.CCDN010000005_gene3377 1.52e-73 223.0 COG1791@1|root,COG1791@2|Bacteria,1TT4W@1239|Firmicutes,4HFN3@91061|Bacilli,1ZFZ5@1386|Bacillus 91061|Bacilli S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway mtnD GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0010309,GO:0016053,GO:0016491,GO:0016701,GO:0016702,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0051213,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.13.11.53,1.13.11.54 ko:K08967 ko00270,ko01100,map00270,map01100 M00034 R07363,R07364 RC01866,RC02018,RC02118 ko00000,ko00001,ko00002,ko01000 - - - ARD k141_1959_2 997296.PB1_02180 5.71e-06 47.4 2BGZV@1|root,32AZY@2|Bacteria,1UB2H@1239|Firmicutes,4IMFA@91061|Bacilli,1ZK0Y@1386|Bacillus 91061|Bacilli S Spo0E like sporulation regulatory protein - - - ko:K06376 - - - - ko00000 - - - SpoOE-like k141_23768_2 1294265.JCM21738_2600 1.7e-114 331.0 COG2846@1|root,COG2846@2|Bacteria,1UYJV@1239|Firmicutes,4HE93@91061|Bacilli,1ZE2Y@1386|Bacillus 91061|Bacilli D Di-iron-containing protein involved in the repair of iron-sulfur clusters scdA GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0030091,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050896,GO:0071704,GO:1901564 - ko:K07322 - - - - ko00000 - - - Hemerythrin,ScdA_N k141_28041_1 218284.CCDN010000002_gene2180 6.46e-99 293.0 COG1714@1|root,COG1714@2|Bacteria,1UWM8@1239|Firmicutes,4HBNM@91061|Bacilli,1ZEG4@1386|Bacillus 91061|Bacilli S RDD family - - - - - - - - - - - - RDD k141_5777_1 218284.CCDN010000006_gene3686 1.46e-60 196.0 COG3012@1|root,COG3012@2|Bacteria,1V8NE@1239|Firmicutes,4HK5V@91061|Bacilli,1ZE7P@1386|Bacillus 91061|Bacilli K SEC-C motif yccF - - ko:K07039 - - - - ko00000 - - - HTH_psq,SEC-C k141_5777_2 218284.CCDN010000006_gene3685 5.02e-21 93.6 COG0653@1|root,COG0653@2|Bacteria,1TPEY@1239|Firmicutes,4HA22@91061|Bacilli,1ZAXF@1386|Bacillus 91061|Bacilli U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW k141_9427_1 218284.CCDN010000002_gene2125 8.06e-155 441.0 COG1171@1|root,COG1171@2|Bacteria,1TP22@1239|Firmicutes,4H9NK@91061|Bacilli,1ZBM0@1386|Bacillus 91061|Bacilli E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA tdcB_1 - 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - - PALP k141_3235_1 491915.Aflv_2791 4.2e-28 108.0 COG0765@1|root,COG0765@2|Bacteria,1TPM3@1239|Firmicutes,4HAS2@91061|Bacilli,21V0A@150247|Anoxybacillus 91061|Bacilli E Binding-protein-dependent transport system inner membrane component - - - ko:K02029 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 k141_3235_2 1034347.CAHJ01000048_gene331 2.72e-20 87.4 COG0834@1|root,COG0834@2|Bacteria,1UXYA@1239|Firmicutes,4H9NJ@91061|Bacilli,1ZBGH@1386|Bacillus 91061|Bacilli ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain - - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 k141_16347_1 218284.CCDN010000002_gene2209 1.49e-76 237.0 COG1744@1|root,COG1744@2|Bacteria,1TPEU@1239|Firmicutes,4HBCY@91061|Bacilli,1ZCTZ@1386|Bacillus 91061|Bacilli S ABC transporter substrate-binding protein PnrA-like - - - ko:K07335 - - - - ko00000 - - - Bmp k141_35509_1 1294265.JCM21738_2888 1.36e-114 338.0 COG0438@1|root,COG0438@2|Bacteria,1V2NV@1239|Firmicutes,4HE1F@91061|Bacilli,1ZS6K@1386|Bacillus 91061|Bacilli M Glycosyl transferases group 1 yqgM - 2.4.1.250 ko:K15521 - - - - ko00000,ko01000 - - - Glyco_transf_4,Glycos_transf_1 k141_7039_1 42565.FP66_06650 6.64e-114 340.0 COG1502@1|root,COG1502@2|Bacteria,1MUDJ@1224|Proteobacteria,1RMIF@1236|Gammaproteobacteria,1XN8A@135619|Oceanospirillales 135619|Oceanospirillales I COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes - - - ko:K06132 ko00564,ko01100,map00564,map01100 - R11062 RC00017 ko00000,ko00001,ko01000 - - - PLDc_2 k141_32932_1 1268239.PALB_23130 8.18e-166 472.0 COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,1RMAQ@1236|Gammaproteobacteria,2Q2AF@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria L COG3547 Transposase and inactivated derivatives ISPlu13C - - - - - - - - - - - DEDD_Tnp_IS110,Transposase_20 k141_32932_2 1117315.AHCA01000001_gene2457 1.42e-132 382.0 28PXN@1|root,2ZCHK@2|Bacteria,1R71P@1224|Proteobacteria,1S2DY@1236|Gammaproteobacteria,2Q24S@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_32932_4 35703.DQ02_04735 6.38e-204 588.0 COG0305@1|root,COG0305@2|Bacteria,1RBU8@1224|Proteobacteria,1T26S@1236|Gammaproteobacteria 1236|Gammaproteobacteria L COG0457 FOG TPR repeat - - - - - - - - - - - - - k141_32932_5 1515746.HR45_16145 3.89e-177 498.0 COG1746@1|root,COG1746@2|Bacteria,1PXVD@1224|Proteobacteria,1TNJD@1236|Gammaproteobacteria,2QE3I@267890|Shewanellaceae 1236|Gammaproteobacteria J tRNA cytidylyltransferase activity - - - - - - - - - - - - - k141_16348_1 1120973.AQXL01000127_gene2748 7.94e-19 85.5 COG0142@1|root,COG0142@2|Bacteria,1TPQY@1239|Firmicutes,4HA8E@91061|Bacilli,278AU@186823|Alicyclobacillaceae 91061|Bacilli H Belongs to the FPP GGPP synthase family ispA GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0071704,GO:1901576 2.5.1.1,2.5.1.10,2.5.1.29 ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00366 R01658,R02003,R02061 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 - - - polyprenyl_synt k141_16348_2 376733.IT41_17625 5.5e-32 124.0 COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,2TRDD@28211|Alphaproteobacteria,2PUJM@265|Paracoccus 28211|Alphaproteobacteria HI Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) dxs - 2.2.1.7 ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 M00096 R05636 RC00032 ko00000,ko00001,ko00002,ko01000 - - - DXP_synthase_N,Transket_pyr,Transketolase_C k141_22433_1 1453501.JELR01000002_gene455 5.35e-58 191.0 COG3782@1|root,COG3782@2|Bacteria,1MZ3U@1224|Proteobacteria,1S9NQ@1236|Gammaproteobacteria,468I5@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF1853) - - - ko:K09977 - - - - ko00000 - - - DUF1853 k141_22433_2 1279017.AQYJ01000028_gene2445 3.14e-104 304.0 COG1510@1|root,COG1510@2|Bacteria,1RA49@1224|Proteobacteria,1RRGB@1236|Gammaproteobacteria,466H1@72275|Alteromonadaceae 1236|Gammaproteobacteria K Belongs to the GbsR family - - - - - - - - - - - - HTH_11,HTH_5,MarR,MarR_2 k141_22433_4 1279017.AQYJ01000028_gene2443 3.26e-183 516.0 COG1294@1|root,COG1294@2|Bacteria,1MURP@1224|Proteobacteria,1RN0N@1236|Gammaproteobacteria,465MU@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1294 Cytochrome bd-type quinol oxidase, subunit 2 cydB - 1.10.3.14 ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - Cyt_bd_oxida_II k141_20984_1 1042377.AFPJ01000023_gene681 1.05e-142 409.0 COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,1RM8G@1236|Gammaproteobacteria,4642K@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives folP GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042221,GO:0042364,GO:0042398,GO:0042493,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046655,GO:0046656,GO:0050896,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.15 ko:K00796 ko00790,ko01100,map00790,map01100 M00126,M00841 R03066,R03067 RC00121,RC00842 ko00000,ko00001,ko00002,ko01000 - - iECO103_1326.ECO103_3924,iPC815.YPO3501 Pterin_bind k141_1072_1 223926.28807834 3.48e-176 496.0 COG1162@1|root,COG1162@2|Bacteria,1MUEF@1224|Proteobacteria,1RMMB@1236|Gammaproteobacteria,1XTBR@135623|Vibrionales 135623|Vibrionales S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit rsgA - 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 - R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 - - - RsgA_GTPase k141_1072_2 1116375.VEJY3_14395 1.53e-208 576.0 COG0688@1|root,COG0688@2|Bacteria,1MVT4@1224|Proteobacteria,1RN1U@1236|Gammaproteobacteria,1XT0P@135623|Vibrionales 135623|Vibrionales I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) psd GO:0003674,GO:0003824,GO:0004609,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0071704,GO:0090407,GO:1901576 4.1.1.65 ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 M00093 R02055 RC00299 ko00000,ko00001,ko00002,ko01000 - - - PS_Dcarbxylase k141_34228_2 223926.28809654 1.51e-88 260.0 COG1846@1|root,COG1846@2|Bacteria,1N244@1224|Proteobacteria,1SPHU@1236|Gammaproteobacteria,1XXB7@135623|Vibrionales 135623|Vibrionales K HxlR-like helix-turn-helix VVA1156 - - - - - - - - - - - MarR k141_34228_3 1116375.VEJY3_17381 4.81e-92 270.0 COG3304@1|root,COG3304@2|Bacteria,1RA96@1224|Proteobacteria,1S1ZC@1236|Gammaproteobacteria,1XWVT@135623|Vibrionales 135623|Vibrionales S Inner membrane component domain yccF - - - - - - - - - - - YccF k141_37624_2 1453501.JELR01000005_gene1615 1.58e-259 720.0 COG1115@1|root,COG1115@2|Bacteria,1MUI3@1224|Proteobacteria,1RMNF@1236|Gammaproteobacteria,4669U@72275|Alteromonadaceae 1236|Gammaproteobacteria E Sodium:alanine symporter family - - - ko:K03310 - - - - ko00000 2.A.25 - - Na_Ala_symp k141_30397_1 1219076.N646_4549 2.54e-167 471.0 COG0583@1|root,COG0583@2|Bacteria,1MU2E@1224|Proteobacteria,1RQ66@1236|Gammaproteobacteria,1XXB6@135623|Vibrionales 135623|Vibrionales K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate k141_30397_2 1219077.VAZ01S_100_00030 1.98e-26 98.2 28R9G@1|root,2ZDP4@2|Bacteria,1P9ZB@1224|Proteobacteria,1SUFH@1236|Gammaproteobacteria,1XZ21@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_30397_3 675815.VOA_000357 5.83e-41 135.0 COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,1XYBB@135623|Vibrionales 135623|Vibrionales K COG1278 Cold shock proteins - - - ko:K03704 - - - - ko00000,ko03000 - - - CSD k141_30397_4 998674.ATTE01000001_gene1932 7.12e-284 789.0 COG1027@1|root,COG1027@2|Bacteria,1R9JY@1224|Proteobacteria,1RP5Z@1236|Gammaproteobacteria,463WQ@72273|Thiotrichales 72273|Thiotrichales E Fumarase C C-terminus - - - - - - - - - - - - FumaraseC_C,Lyase_1,cNMP_binding k141_31552_2 1042377.AFPJ01000021_gene2134 1.37e-34 120.0 2DQRC@1|root,32UPM@2|Bacteria,1N3E5@1224|Proteobacteria,1S9S7@1236|Gammaproteobacteria,46C1U@72275|Alteromonadaceae 1236|Gammaproteobacteria - - VPA0120 - - - - - - - - - - - - k141_31552_3 1279017.AQYJ01000024_gene853 6.12e-175 498.0 COG3213@1|root,COG3213@2|Bacteria,1MUJK@1224|Proteobacteria,1RMCR@1236|Gammaproteobacteria,466R8@72275|Alteromonadaceae 1236|Gammaproteobacteria P protein involved in response to NO nnrS - - ko:K07234 - - - - ko00000 - - - NnrS k141_29412_1 398511.BpOF4_09290 2.62e-21 84.7 COG1826@1|root,COG1826@2|Bacteria,1VFP2@1239|Firmicutes,4HNM7@91061|Bacilli,1ZIUG@1386|Bacillus 91061|Bacilli U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system tatA - - ko:K03116 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - MttA_Hcf106 k141_29412_2 218284.CCDN010000011_gene4408 2.89e-149 421.0 COG2344@1|root,COG2344@2|Bacteria,1TSMR@1239|Firmicutes,4HB7Q@91061|Bacilli,1ZANM@1386|Bacillus 91061|Bacilli K Modulates transcription in response to changes in cellular NADH NAD( ) redox state rex - - ko:K01926 - - - - ko00000,ko03000 - - - CoA_binding,Put_DNA-bind_N k141_29412_3 218284.CCDN010000011_gene4407 0.0 939.0 COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4HBVV@91061|Bacilli,1ZB7Z@1386|Bacillus 91061|Bacilli S ABC transporter ydiF - - ko:K06158 - - - - ko00000,ko03012 - - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn k141_22434_1 218284.CCDN010000001_gene1810 8.09e-88 265.0 COG1388@1|root,COG1388@2|Bacteria,1V5FY@1239|Firmicutes,4HFU9@91061|Bacilli,1ZDDF@1386|Bacillus 91061|Bacilli M LysM domain - - - - - - - - - - - - - k141_3236_1 42565.FP66_14455 4.84e-101 306.0 COG0534@1|root,COG0534@2|Bacteria,1MUAM@1224|Proteobacteria,1RP5M@1236|Gammaproteobacteria,1XHCU@135619|Oceanospirillales 135619|Oceanospirillales V MATE efflux family protein - - - ko:K03327 - - - - ko00000,ko02000 2.A.66.1 - - MatE k141_36409_1 946235.CAER01000051_gene1687 1.38e-09 57.4 COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,4HA7D@91061|Bacilli,23III@182709|Oceanobacillus 91061|Bacilli T Transcriptional regulatory protein, C terminal resD - - ko:K07775 ko02020,map02020 M00458 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C k141_36409_2 218284.CCDN010000001_gene1064 3.06e-49 172.0 COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HBZ0@91061|Bacilli,1ZAQC@1386|Bacillus 91061|Bacilli T Histidine kinase resE - 2.7.13.3 ko:K07651 ko02020,map02020 M00458 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,PAS,PAS_4 k141_24760_7 319224.Sputcn32_0911 1.16e-36 127.0 2B74X@1|root,3206C@2|Bacteria,1QDHC@1224|Proteobacteria,1TBVH@1236|Gammaproteobacteria,2QD5R@267890|Shewanellaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_24760_10 400668.Mmwyl1_0984 3.68e-21 90.5 2E19G@1|root,33FUG@2|Bacteria,1NI1I@1224|Proteobacteria,1SJDV@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_3256_1 333138.LQ50_15595 4.59e-74 230.0 COG3910@1|root,COG3910@2|Bacteria,1TSWP@1239|Firmicutes,4HBQT@91061|Bacilli,1ZCVC@1386|Bacillus 91061|Bacilli S AAA domain cysA1 - - - - - - - - - - - AAA_21,AAA_23 k141_22464_1 1279009.ADICEAN_00534 2.52e-26 112.0 COG1404@1|root,COG1404@2|Bacteria 2|Bacteria O Belongs to the peptidase S8 family isp - - ko:K13275 - - - - ko00000,ko01000,ko01002,ko03110 - - - Peptidase_S8 k141_22464_2 266117.Rxyl_0743 2.06e-70 225.0 COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,2GJB6@201174|Actinobacteria,4CPTD@84995|Rubrobacteria 84995|Rubrobacteria HP UBA THIF-type NAD FAD binding - - 2.7.7.80,2.8.1.11 ko:K21147 ko04122,map04122 - R07459,R07461 RC00043 ko00000,ko00001,ko01000 - - - Rhodanese,ThiF k141_34246_1 1279017.AQYJ01000027_gene1569 0.0 1035.0 COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,1RM89@1236|Gammaproteobacteria,464TH@72275|Alteromonadaceae 1236|Gammaproteobacteria L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex mutL GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K03572 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - DNA_mis_repair,HATPase_c_3,MutL_C k141_29454_1 1227739.Hsw_1315 2.59e-16 80.9 COG3975@1|root,COG3975@2|Bacteria,4NE4D@976|Bacteroidetes,47NWB@768503|Cytophagia 976|Bacteroidetes S M61 glycyl aminopeptidase - - - - - - - - - - - - PDZ_2,Peptidase_M61 k141_1993_1 1294265.JCM21738_3096 1.26e-89 264.0 COG2225@1|root,COG2225@2|Bacteria,1TPE8@1239|Firmicutes,4H9ST@91061|Bacilli,1ZBY7@1386|Bacillus 91061|Bacilli C Belongs to the malate synthase family aceB - 2.3.3.9 ko:K01638 ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200 M00012 R00472 RC00004,RC00308,RC02747 ko00000,ko00001,ko00002,ko01000 - - - Malate_synthase k141_16379_2 999141.GME_00665 3.88e-05 44.7 COG0245@1|root,COG0245@2|Bacteria,1MVHA@1224|Proteobacteria,1S3RQ@1236|Gammaproteobacteria,1XJPI@135619|Oceanospirillales 135619|Oceanospirillales I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) ispF - 4.6.1.12 ko:K01770 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05637 RC00002,RC01440 ko00000,ko00001,ko00002,ko01000 - - - YgbB k141_20045_1 1042377.AFPJ01000054_gene1692 8.77e-81 252.0 COG0415@1|root,COG0415@2|Bacteria,1MWRT@1224|Proteobacteria,1RN1P@1236|Gammaproteobacteria,465QF@72275|Alteromonadaceae 1236|Gammaproteobacteria L Belongs to the DNA photolyase family cry GO:0003674,GO:0003824,GO:0003904,GO:0003913,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 4.1.99.3 ko:K01669 - - - - ko00000,ko01000,ko03400 - - - DNA_photolyase,FAD_binding_7 k141_26074_1 1280001.BAOA01000027_gene4825 3.97e-151 455.0 COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,1RM9A@1236|Gammaproteobacteria,1XUE7@135623|Vibrionales 135623|Vibrionales D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins ftsK - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma k141_26074_2 1116375.VEJY3_05420 6.86e-135 383.0 COG2834@1|root,COG2834@2|Bacteria,1PXDV@1224|Proteobacteria,1S9FW@1236|Gammaproteobacteria,1XU2P@135623|Vibrionales 135623|Vibrionales M Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) lolA GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - ko:K03634 - - - - ko00000 - - - LolA k141_26074_3 223926.28806094 0.0 865.0 COG2256@1|root,COG2256@2|Bacteria,1MUVS@1224|Proteobacteria,1RPBY@1236|Gammaproteobacteria,1XUU2@135623|Vibrionales 135623|Vibrionales L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase rarA - - ko:K07478 - - - - ko00000 - - - AAA,AAA_assoc_2,MgsA_C k141_26074_4 1280001.BAOA01000027_gene4822 7.58e-303 827.0 COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,1RNAQ@1236|Gammaproteobacteria,1XUNW@135623|Vibrionales 135623|Vibrionales J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) serS GO:0003674,GO:0003824,GO:0004812,GO:0004828,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006434,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Seryl_tRNA_N,tRNA-synt_2b k141_26074_5 1116375.VEJY3_05435 3.18e-299 817.0 COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,1RP0W@1236|Gammaproteobacteria,1XTG0@135623|Vibrionales 135623|Vibrionales H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor bioA - 2.6.1.62 ko:K00833 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R03231 RC00006,RC00887 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 k141_26074_6 1116375.VEJY3_05440 3e-250 687.0 COG0502@1|root,COG0502@2|Bacteria,1MVFF@1224|Proteobacteria,1RMEQ@1236|Gammaproteobacteria,1XTAY@135623|Vibrionales 135623|Vibrionales H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism bioB GO:0003674,GO:0003824,GO:0004076,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.6 ko:K01012 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R01078 RC00441 ko00000,ko00001,ko00002,ko01000 - - - BATS,Radical_SAM k141_26074_7 1116375.VEJY3_05445 1.17e-250 691.0 COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,1RNS6@1236|Gammaproteobacteria,1XTHY@135623|Vibrionales 135623|Vibrionales H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide bioF GO:0003674,GO:0003824,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008710,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.3.1.47 ko:K00652 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R03210,R10124 RC00004,RC00039,RC02725 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k141_36432_1 1247963.JPHU01000020_gene2984 3.2e-16 82.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,2TTJG@28211|Alphaproteobacteria 28211|Alphaproteobacteria P receptor - - - - - - - - - - - - Plug,TonB_dep_Rec k141_21006_1 767817.Desgi_1853 3.12e-16 79.3 COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,248RW@186801|Clostridia,260DE@186807|Peptococcaceae 186801|Clostridia J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction pnp - 2.7.7.8 ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 M00394 R00437,R00438,R00439,R00440 RC02795 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 - - - KH_1,PNPase,RNase_PH,RNase_PH_C,S1 k141_21006_2 117187.FVEG_06659T0 1.38e-13 72.0 COG1282@1|root,2QQ0A@2759|Eukaryota,38CB0@33154|Opisthokonta,3NYXQ@4751|Fungi,3QKYV@4890|Ascomycota,21582@147550|Sordariomycetes,3TDAT@5125|Hypocreales,1FN2W@110618|Nectriaceae 4751|Fungi C NAD(P) transhydrogenase, mitochondrial precursor - - 1.6.1.2 ko:K00323 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - AlaDh_PNT_C,AlaDh_PNT_N,PNTB,PNTB_4TM k141_24761_1 218284.CCDN010000002_gene2135 1.34e-69 231.0 COG0210@1|root,COG0210@2|Bacteria,1TPVG@1239|Firmicutes,4HBVF@91061|Bacilli,1ZCF6@1386|Bacillus 91061|Bacilli L DNA helicase yjcD - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C,YdjO k141_32977_1 1294265.JCM21738_476 1.36e-72 219.0 COG1765@1|root,COG1765@2|Bacteria,1V78R@1239|Firmicutes,4HMM3@91061|Bacilli,1ZH2T@1386|Bacillus 91061|Bacilli O OsmC-like protein - - - - - - - - - - - - OsmC k141_29456_1 218284.CCDN010000001_gene1506 6.93e-63 213.0 COG1048@1|root,COG1048@2|Bacteria,1VTMM@1239|Firmicutes,4HB5N@91061|Bacilli,1ZART@1386|Bacillus 91061|Bacilli C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate citB GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0043937,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0050789,GO:0050793,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0065007,GO:0071704,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_C k141_22465_2 1279017.AQYJ01000024_gene1055 1.67e-135 395.0 COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,4645J@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain degS GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009897,GO:0009986,GO:0009987,GO:0010033,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031975,GO:0033554,GO:0035966,GO:0035967,GO:0042221,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051716,GO:0051788,GO:0070011,GO:0070887,GO:0071218,GO:0071310,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0140096,GO:1901564 - ko:K04691,ko:K04772 - - - - ko00000,ko01000,ko01002 - - - PDZ_2,Trypsin_2 k141_9444_1 1279017.AQYJ01000027_gene1928 6.34e-45 153.0 COG3087@1|root,COG3087@2|Bacteria,1MYFG@1224|Proteobacteria,1S9Y3@1236|Gammaproteobacteria,467S5@72275|Alteromonadaceae 1236|Gammaproteobacteria D COG3087 Cell division protein - - - ko:K03591 - - - - ko00000,ko03036 - - - SPOR k141_4441_1 9707.XP_004408476.1 7.27e-10 64.7 COG2249@1|root,2QRQH@2759|Eukaryota,39R05@33154|Opisthokonta,3BH89@33208|Metazoa,3CYXD@33213|Bilateria,4884P@7711|Chordata,496QK@7742|Vertebrata,3J91M@40674|Mammalia,3EGJ6@33554|Carnivora 33208|Metazoa S dehydrogenase (quinone) NQO2 GO:0000166,GO:0001512,GO:0001932,GO:0001934,GO:0003008,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0006091,GO:0007610,GO:0007611,GO:0007613,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0008284,GO:0009055,GO:0009893,GO:0009966,GO:0009967,GO:0009987,GO:0010562,GO:0010604,GO:0010646,GO:0010647,GO:0010941,GO:0010942,GO:0016491,GO:0016661,GO:0019220,GO:0019222,GO:0022900,GO:0023051,GO:0023056,GO:0031323,GO:0031325,GO:0031399,GO:0031401,GO:0031404,GO:0031974,GO:0031981,GO:0032268,GO:0032270,GO:0032501,GO:0033218,GO:0036094,GO:0042127,GO:0042325,GO:0042327,GO:0042562,GO:0042802,GO:0042803,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043408,GO:0043410,GO:0043523,GO:0043525,GO:0044237,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0045937,GO:0046872,GO:0046914,GO:0046983,GO:0048037,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0048660,GO:0048661,GO:0050660,GO:0050662,GO:0050789,GO:0050794,GO:0050877,GO:0050890,GO:0051171,GO:0051173,GO:0051174,GO:0051246,GO:0051247,GO:0055114,GO:0060255,GO:0065007,GO:0070013,GO:0070372,GO:0070374,GO:0071949,GO:0080090,GO:0097159,GO:1901214,GO:1901216,GO:1901265,GO:1901363,GO:1902531,GO:1902533,GO:1904408,GO:1904705,GO:1904707,GO:1905594,GO:2000377,GO:2000379 1.10.5.1 ko:K08071 - - - - ko00000,ko01000 - - - Flavodoxin_2 k141_35537_2 218284.CCDN010000001_gene1905 1.64e-73 224.0 COG1871@1|root,COG1871@2|Bacteria,1V70X@1239|Firmicutes,4HIVG@91061|Bacilli,1ZGE3@1386|Bacillus 91061|Bacilli NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase cheD - 3.5.1.44 ko:K03411 ko02030,map02030 - - - ko00000,ko00001,ko01000,ko02035 - - - CheD k141_35537_3 218284.CCDN010000001_gene1906 4.64e-109 318.0 COG1776@1|root,COG1776@2|Bacteria,1UNKB@1239|Firmicutes,4HB40@91061|Bacilli,1ZDIE@1386|Bacillus 91061|Bacilli NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation cheC GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0050896,GO:0050918 - ko:K03410 ko02030,map02030 - - - ko00000,ko00001,ko02035 - - - CheC,CheX k141_35537_4 1307436.PBF_07591 5.21e-57 182.0 COG0835@1|root,COG0835@2|Bacteria,1V4HH@1239|Firmicutes,4HHB5@91061|Bacilli,1ZGZE@1386|Bacillus 91061|Bacilli NT COG0835 Chemotaxis signal transduction protein cheW GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006935,GO:0008150,GO:0009453,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0042333,GO:0044424,GO:0044444,GO:0044464,GO:0050896 - ko:K03408 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - CheW k141_1995_1 1294265.JCM21738_1806 1.13e-05 47.4 COG2010@1|root,COG2010@2|Bacteria,1VIMV@1239|Firmicutes,4HWR2@91061|Bacilli,1ZGNH@1386|Bacillus 91061|Bacilli C Cytochrome c - - - - - - - - - - - - - k141_1092_1 247634.GPB2148_369 1.03e-13 73.6 COG2267@1|root,COG2267@2|Bacteria,1MWDA@1224|Proteobacteria,1RRJP@1236|Gammaproteobacteria,1JACR@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria I Serine aminopeptidase, S33 pldB GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0008150,GO:0008152,GO:0016020,GO:0016298,GO:0016740,GO:0016746,GO:0016747,GO:0016787,GO:0016788,GO:0044238,GO:0044464,GO:0052689,GO:0071704,GO:0071944 3.1.1.5 ko:K01048 ko00564,map00564 - - - ko00000,ko00001,ko01000 - - iETEC_1333.ETEC_4102,iEcHS_1320.EcHS_A4049 Hydrolase_4 k141_9445_2 1408224.SAMCCGM7_c1851 4.07e-10 63.5 COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,4BA4K@82115|Rhizobiaceae 28211|Alphaproteobacteria T Adenylate cyclase - - - - - - - - - - - - Guanylate_cyc k141_5811_1 1279017.AQYJ01000029_gene3461 5.5e-115 339.0 COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,1RNN9@1236|Gammaproteobacteria,464N3@72275|Alteromonadaceae 1236|Gammaproteobacteria OU COG0616 Periplasmic serine proteases (ClpP class) sohB GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0016020,GO:0019538,GO:0043170,GO:0044238,GO:0044464,GO:0071704,GO:0071944,GO:1901564 - ko:K04774 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S49,Peptidase_S49_N k141_5811_2 1042377.AFPJ01000031_gene577 3.02e-196 549.0 COG0604@1|root,COG0604@2|Bacteria,1MV3W@1224|Proteobacteria,1RMHG@1236|Gammaproteobacteria,4640J@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases yhfP - 1.1.1.1 ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N k141_5811_3 1453501.JELR01000001_gene2607 1.29e-236 658.0 COG1752@1|root,COG1752@2|Bacteria,1PDQ2@1224|Proteobacteria,1RMWI@1236|Gammaproteobacteria,4641T@72275|Alteromonadaceae 1236|Gammaproteobacteria S esterase of the alpha-beta hydrolase superfamily - - - ko:K07001 - - - - ko00000 - - - Patatin k141_5811_4 1453501.JELR01000001_gene2606 1.62e-94 283.0 2DFIW@1|root,32U5K@2|Bacteria,1N3SV@1224|Proteobacteria,1S9V3@1236|Gammaproteobacteria,468SS@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF4919) - - - - - - - - - - - - DUF4919 k141_5811_5 1279017.AQYJ01000026_gene112 0.0 1106.0 COG0210@1|root,COG0210@2|Bacteria,1MXWE@1224|Proteobacteria,1RP5D@1236|Gammaproteobacteria,466UN@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG0210 Superfamily I DNA and RNA helicases uvrD-2 - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C k141_32979_1 1347086.CCBA010000033_gene737 1.83e-73 233.0 COG1388@1|root,COG3858@1|root,COG1388@2|Bacteria,COG3858@2|Bacteria,1TQK2@1239|Firmicutes,4HBJC@91061|Bacilli,1ZBQC@1386|Bacillus 91061|Bacilli M Glycoside Hydrolase Family - - - ko:K06306 - - - - ko00000 - - - Glyco_hydro_18,LysM k141_1093_1 218284.CCDN010000002_gene2146 2.13e-122 359.0 COG0026@1|root,COG0026@2|Bacteria,1TTDR@1239|Firmicutes,4HDHY@91061|Bacilli 91061|Bacilli F Carboxylate--amine ligase - - - - - - - - - - - - ATP-grasp_4 k141_5812_1 379066.GAU_1150 7.26e-21 97.4 COG5000@1|root,COG5000@2|Bacteria,1ZSZU@142182|Gemmatimonadetes 142182|Gemmatimonadetes T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - - - - - - - - - - HATPase_c k141_4443_1 1453501.JELR01000005_gene1665 1.74e-92 304.0 COG2982@1|root,COG2982@2|Bacteria,1MUME@1224|Proteobacteria,1RNPC@1236|Gammaproteobacteria,464KK@72275|Alteromonadaceae 1236|Gammaproteobacteria M Domain of Unknown Function (DUF748) - - - - - - - - - - - - DUF748,OmpA k141_16381_1 1453501.JELR01000002_gene1252 6.67e-233 657.0 COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,1RPZ7@1236|Gammaproteobacteria,464GR@72275|Alteromonadaceae 1236|Gammaproteobacteria L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA priA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006276,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0010332,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042221,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0046677,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - ko:K04066 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,ResIII k141_36774_2 768671.ThimaDRAFT_1732 1.73e-19 86.3 COG4313@1|root,COG4313@2|Bacteria,1PC95@1224|Proteobacteria,1RZJZ@1236|Gammaproteobacteria,1WZES@135613|Chromatiales 135613|Chromatiales C Putative MetA-pathway of phenol degradation - - - - - - - - - - - - Phenol_MetA_deg k141_30796_1 218284.CCDN010000002_gene2793 9.09e-128 385.0 COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,4HA3G@91061|Bacilli,1ZAVY@1386|Bacillus 91061|Bacilli T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,PAS_3,PAS_4,PAS_9 k141_36776_1 441769.ABFU01000050_gene3955 1.88e-37 126.0 COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,4HNJC@91061|Bacilli,1ZHSU@1386|Bacillus 91061|Bacilli K Cold shock - - - ko:K03704 - - - - ko00000,ko03000 - - - CSD k141_31900_1 1453501.JELR01000002_gene591 4.27e-95 284.0 COG3047@1|root,COG3047@2|Bacteria,1NUZJ@1224|Proteobacteria,1RRRC@1236|Gammaproteobacteria,467CK@72275|Alteromonadaceae 1236|Gammaproteobacteria M Outer membrane protein W ompW - - ko:K07275 - - - - ko00000 - - - OmpW k141_15428_1 1294265.JCM21738_658 1.46e-99 296.0 COG0113@1|root,COG0113@2|Bacteria,1TP09@1239|Firmicutes,4HBQC@91061|Bacilli,1ZARK@1386|Bacillus 91061|Bacilli H Belongs to the ALAD family hemB GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00036 RC00918,RC01781 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ALAD k141_15428_2 666686.B1NLA3E_16795 1.08e-18 83.6 COG1587@1|root,COG1587@2|Bacteria,1UHSJ@1239|Firmicutes,4HFY4@91061|Bacilli,1ZGER@1386|Bacillus 91061|Bacilli H Uroporphyrinogen-III synthase hemD - 4.2.1.75 ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R03165 RC01861 ko00000,ko00001,ko00002,ko01000 - - - HEM4 k141_36777_2 218284.CCDN010000005_gene3368 1.7e-59 187.0 COG0350@1|root,COG0350@2|Bacteria,1VA03@1239|Firmicutes,4HKC0@91061|Bacilli,1ZGW4@1386|Bacillus 91061|Bacilli L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated ogt GO:0003674,GO:0003824,GO:0003908,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 2.1.1.63 ko:K00567,ko:K13531 - - - - ko00000,ko01000,ko03400 - - - DNA_binding_1,Methyltransf_1N k141_31901_1 1116375.VEJY3_20101 1.04e-98 297.0 COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,1RP04@1236|Gammaproteobacteria,1XTGB@135623|Vibrionales 135623|Vibrionales H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans glgC2 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008878,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0070566,GO:0071704,GO:1901576 2.7.7.27 ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase k141_15430_1 1453501.JELR01000001_gene3099 7.24e-40 142.0 2ECIV@1|root,336H0@2|Bacteria,1NA3Q@1224|Proteobacteria,1SDUX@1236|Gammaproteobacteria,46CAE@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_36778_2 1279017.AQYJ01000024_gene1069 7.53e-26 107.0 COG0501@1|root,COG0501@2|Bacteria,1MVU4@1224|Proteobacteria,1RPJ5@1236|Gammaproteobacteria,46584@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG0501 Zn-dependent protease with chaperone function htpX - - ko:K03799 - M00743 - - ko00000,ko00002,ko01000,ko01002 - - - Peptidase_M48 k141_30798_1 218284.CCDN010000006_gene3584 1.48e-189 536.0 COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,4HADX@91061|Bacilli 91061|Bacilli E Belongs to the aspartokinase family - - - - - - - - - - - - AA_kinase,ACT_7 k141_30798_2 218284.CCDN010000006_gene3585 1.57e-121 358.0 COG0460@1|root,COG0460@2|Bacteria,1TQ2H@1239|Firmicutes,4HBAP@91061|Bacilli,1ZCGH@1386|Bacillus 91061|Bacilli E homoserine dehydrogenase - - 1.1.1.3 ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00017,M00018 R01773,R01775 RC00087 ko00000,ko00001,ko00002,ko01000 - - - Homoserine_dh,NAD_binding_3 k141_15431_1 218284.CCDN010000002_gene2777 3.34e-108 339.0 COG0369@1|root,COG2124@1|root,COG0369@2|Bacteria,COG2124@2|Bacteria,1TS1E@1239|Firmicutes,4HCWS@91061|Bacilli,1ZQAP@1386|Bacillus 91061|Bacilli C Belongs to the cytochrome P450 family yrhJ GO:0000166,GO:0003674,GO:0003824,GO:0003958,GO:0004497,GO:0005488,GO:0005504,GO:0005506,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008289,GO:0009987,GO:0010181,GO:0016491,GO:0016651,GO:0016653,GO:0016705,GO:0016712,GO:0019395,GO:0019752,GO:0020037,GO:0030258,GO:0031406,GO:0032553,GO:0032787,GO:0033293,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363 1.14.14.1,1.6.2.4 ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 - R03629,R04121,R05259 RC00046,RC01311 ko00000,ko00001,ko00199,ko01000 - - - FAD_binding_1,Flavodoxin_1,NAD_binding_1,p450 k141_30799_1 218284.CCDN010000001_gene144 2.3e-72 224.0 COG0483@1|root,COG0483@2|Bacteria,1TR4E@1239|Firmicutes,4HB92@91061|Bacilli,1ZAS1@1386|Bacillus 91061|Bacilli G Inositol monophosphatase suhB GO:0003674,GO:0003824,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 - - - Inositol_P k141_30800_1 1132442.KB889752_gene606 1.17e-65 204.0 2ABH1@1|root,310Y3@2|Bacteria,1V4IK@1239|Firmicutes,4HI56@91061|Bacilli,1ZGD1@1386|Bacillus 91061|Bacilli S YkyB-like protein ykyB - - - - - - - - - - - YkyB k141_30801_2 218284.CCDN010000001_gene1719 4.23e-61 193.0 COG0500@1|root,COG2226@2|Bacteria,1TR6N@1239|Firmicutes,4ISTQ@91061|Bacilli,1ZS6J@1386|Bacillus 91061|Bacilli Q Protein of unknown function (DUF1698) - - - - - - - - - - - - Methyltransf_11,Methyltransf_12,Methyltransf_23,Methyltransf_25,Methyltransf_31 k141_31906_1 1042377.AFPJ01000052_gene1537 4.12e-103 322.0 COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,1MVI9@1224|Proteobacteria,1RNB0@1236|Gammaproteobacteria,46617@72275|Alteromonadaceae 1236|Gammaproteobacteria D protein involved in exopolysaccharide biosynthesis - - - ko:K16554,ko:K16692 ko05111,map05111 - - - ko00000,ko00001,ko01000,ko01001,ko02000 8.A.3.1 - - AAA_31,CbiA,GNVR,Wzz k141_7148_2 1340434.AXVA01000008_gene3754 4.45e-57 194.0 COG0151@1|root,COG0151@2|Bacteria,1UR8C@1239|Firmicutes,4IS9W@91061|Bacilli,1ZF4M@1386|Bacillus 91061|Bacilli F Biotin carboxylase - - - - - - - - - - - - ATP-grasp_4 k141_28561_1 218284.CCDN010000001_gene686 1.56e-93 276.0 COG1268@1|root,COG1268@2|Bacteria,1TS7R@1239|Firmicutes,4HC1H@91061|Bacilli,1ZCIP@1386|Bacillus 91061|Bacilli S Biotin biosynthesis protein bioY - - ko:K03523 ko02010,map02010 M00581,M00582 - - ko00000,ko00001,ko00002,ko02000 2.A.88.1,2.A.88.2 - - BioY k141_33311_1 1279017.AQYJ01000025_gene701 9.61e-79 259.0 COG2887@1|root,COG2887@2|Bacteria,1QVX1@1224|Proteobacteria,1RP9I@1236|Gammaproteobacteria,465DQ@72275|Alteromonadaceae 1236|Gammaproteobacteria L PD-(D/E)XK nuclease superfamily lidB - - - - - - - - - - - PDDEXK_1 k141_19044_1 218284.CCDN010000001_gene1231 4e-180 513.0 COG0793@1|root,COG0793@2|Bacteria,1TPBI@1239|Firmicutes,4HAKE@91061|Bacilli,1ZBDE@1386|Bacillus 91061|Bacilli M Belongs to the peptidase S41A family ctpA GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016787,GO:0019538,GO:0023052,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - PDZ,PDZ_2,PG_binding_1,Peptidase_S41 k141_34499_2 1347086.CCBA010000014_gene686 9.61e-29 103.0 COG1841@1|root,COG1841@2|Bacteria,1VEG4@1239|Firmicutes,4HNHF@91061|Bacilli,1ZITD@1386|Bacillus 91061|Bacilli J Ribosomal protein L30 rpmD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02907 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L30 k141_34499_3 997296.PB1_06567 6.67e-101 294.0 COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,4HFN4@91061|Bacilli,1ZBWE@1386|Bacillus 91061|Bacilli J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body rpsE GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02988 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S5,Ribosomal_S5_C k141_22607_2 1382358.JHVN01000013_gene1812 1.24e-55 181.0 COG3483@1|root,COG3483@2|Bacteria,1TR14@1239|Firmicutes,4H9X1@91061|Bacilli 91061|Bacilli E Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety kynA GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019752,GO:0020037,GO:0022607,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.11 ko:K00453 ko00380,ko01100,map00380,map01100 M00038 R00678 RC00356 ko00000,ko00001,ko00002,ko01000 - - - Trp_dioxygenase k141_17850_1 218284.CCDN010000007_gene3786 4.35e-280 785.0 COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,4HAHY@91061|Bacilli,1ZB8F@1386|Bacillus 91061|Bacilli L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrA - 5.99.1.3 ko:K02469 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseA_C,DNA_topoisoIV k141_13103_1 218284.CCDN010000002_gene2278 2.05e-103 306.0 COG1131@1|root,COG1131@2|Bacteria,1TPMQ@1239|Firmicutes,4HA8K@91061|Bacilli,1ZAYW@1386|Bacillus 91061|Bacilli V COG1131 ABC-type multidrug transport system, ATPase component - - - ko:K01990,ko:K11050 ko02010,map02010 M00254,M00298 - - ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.130 - - ABC_tran k141_16656_1 1232683.ADIMK_0133 8.94e-07 51.2 28IBE@1|root,2Z8DX@2|Bacteria,1NC7D@1224|Proteobacteria,1RP6N@1236|Gammaproteobacteria,4641D@72275|Alteromonadaceae 1236|Gammaproteobacteria S Putative amidoligase enzyme - - - - - - - - - - - - Amidoligase_2 k141_16656_2 1279017.AQYJ01000027_gene1559 6.48e-189 531.0 COG3608@1|root,COG3608@2|Bacteria,1MUAA@1224|Proteobacteria,1RNQQ@1236|Gammaproteobacteria,464DJ@72275|Alteromonadaceae 1236|Gammaproteobacteria S Succinylglutamate desuccinylase aspartoacylase - - - ko:K06987 - - - - ko00000 - - - AstE_AspA k141_16656_3 1042377.AFPJ01000032_gene2786 7.12e-218 610.0 COG2951@1|root,COG3409@1|root,COG2951@2|Bacteria,COG3409@2|Bacteria,1MUZ3@1224|Proteobacteria,1RMQ6@1236|Gammaproteobacteria,464NU@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG2951 Membrane-bound lytic murein transglycosylase B - - 5.1.3.15 ko:K01792,ko:K08305 ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130 - R02739 RC00563 ko00000,ko00001,ko01000,ko01011 - GH103 - Aldose_epim,PG_binding_1,SLT_2 k141_15487_1 1453501.JELR01000002_gene825 2.66e-129 400.0 COG3866@1|root,COG3866@2|Bacteria,1QPFF@1224|Proteobacteria,1RQEM@1236|Gammaproteobacteria,465CX@72275|Alteromonadaceae 1236|Gammaproteobacteria G Amb_all pel1C - - - - - - - - - - - CBM_35,CBM_5_12_2,CBM_6,Pec_lyase_C,RicinB_lectin_2 k141_20223_1 1415755.JQLV01000001_gene3520 8.74e-80 251.0 COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,1RP7E@1236|Gammaproteobacteria,1XKS7@135619|Oceanospirillales 135619|Oceanospirillales J Amidase - - 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Amidase k141_19045_1 1147.D082_26330 2.08e-63 206.0 COG0409@1|root,COG0409@2|Bacteria,1G0NJ@1117|Cyanobacteria,1H6IT@1142|Synechocystis 1117|Cyanobacteria O Hydrogenase formation hypA family hypD - - ko:K04654 - - - - ko00000 - - - HypD k141_4786_1 1212548.B381_08824 6.08e-216 619.0 COG0515@1|root,COG0631@1|root,COG0515@2|Bacteria,COG0631@2|Bacteria,1MV1P@1224|Proteobacteria,1RNQN@1236|Gammaproteobacteria,1Z1XH@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria KLT Serine threonine protein phosphatase - - 3.1.3.16 ko:K01090,ko:K20074 - - - - ko00000,ko01000,ko01009 - - - PP2C_2,Pkinase k141_4786_2 398527.Bphyt_0220 5.23e-83 247.0 COG1513@1|root,COG1513@2|Bacteria,1R9X0@1224|Proteobacteria,2VQ5F@28216|Betaproteobacteria,1K71N@119060|Burkholderiaceae 28216|Betaproteobacteria P Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide cynS - 4.2.1.104 ko:K01725 ko00910,map00910 - R03546,R10079 RC00952 ko00000,ko00001,ko01000 - - - Cyanate_lyase k141_3597_1 1453501.JELR01000001_gene2929 0.0 1105.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,466AN@72275|Alteromonadaceae 1236|Gammaproteobacteria V AcrB/AcrD/AcrF family bepG - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran k141_11905_2 1278306.KB906919_gene1309 4.79e-10 67.4 COG0305@1|root,COG0305@2|Bacteria,3784X@32066|Fusobacteria 32066|Fusobacteria L Participates in initiation and elongation during chromosome replication dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k141_16657_1 218284.CCDN010000001_gene1420 6.05e-21 85.5 COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,4HHA1@91061|Bacilli,1ZFRG@1386|Bacillus 91061|Bacilli O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides ppiB - 5.2.1.8 ko:K03768 - - - - ko00000,ko01000,ko03110 - - - Pro_isomerase k141_13104_2 218284.CCDN010000002_gene2720 9.44e-33 115.0 COG0789@1|root,COG0789@2|Bacteria,1V3QI@1239|Firmicutes,4IPUS@91061|Bacilli,1ZREA@1386|Bacillus 91061|Bacilli K helix_turn_helix, mercury resistance - - - - - - - - - - - - MerR_1 k141_30927_2 1042377.AFPJ01000007_gene1876 7.54e-113 336.0 COG1463@1|root,COG1463@2|Bacteria,1MU4B@1224|Proteobacteria,1S5E8@1236|Gammaproteobacteria,46BX6@72275|Alteromonadaceae 1236|Gammaproteobacteria Q MlaD protein - - - ko:K02067 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaD k141_34500_1 1294265.JCM21738_2098 1.07e-187 529.0 COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,4ISRZ@91061|Bacilli,1ZQ9G@1386|Bacillus 91061|Bacilli S Domain of unknown function DUF21 - - - - - - - - - - - - CBS,CorC_HlyC,DUF21 k141_28562_1 83406.HDN1F_36380 5.81e-128 374.0 COG0596@1|root,COG0596@2|Bacteria,1QVQK@1224|Proteobacteria,1RZ4K@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Alpha/beta hydrolase family - - - ko:K22318 - - - - ko00000 - - - Abhydrolase_1 k141_29737_1 1294265.JCM21738_4871 4.51e-106 314.0 COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4HBVV@91061|Bacilli,1ZB7Z@1386|Bacillus 91061|Bacilli S ABC transporter ydiF - - ko:K06158 - - - - ko00000,ko03012 - - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn k141_32113_1 469383.Cwoe_3280 1.79e-79 247.0 COG1062@1|root,COG1062@2|Bacteria,2GM8C@201174|Actinobacteria,4CPTW@84995|Rubrobacteria 84995|Rubrobacteria C Zinc-binding dehydrogenase - - 1.1.1.1,1.1.1.284 ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 - R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N k141_26_1 42565.FP66_10925 6.66e-90 265.0 COG4341@1|root,COG4341@2|Bacteria,1QHQD@1224|Proteobacteria,1S2ZI@1236|Gammaproteobacteria,1XK7Y@135619|Oceanospirillales 135619|Oceanospirillales S phosphohydrolase - - - - - - - - - - - - HD k141_26_2 768066.HELO_2759 2.89e-09 57.4 COG2175@1|root,COG2175@2|Bacteria,1MX7P@1224|Proteobacteria,1S1JW@1236|Gammaproteobacteria,1XNFE@135619|Oceanospirillales 135619|Oceanospirillales Q Taurine catabolism dioxygenase TauD, TfdA family - - 1.14.11.1 ko:K00471 ko00310,map00310 - R02397 RC00709 ko00000,ko00001,ko01000 - - - DUF971,TauD k141_21432_1 314265.R2601_14735 7.95e-101 301.0 COG1420@1|root,COG1420@2|Bacteria,1MVX4@1224|Proteobacteria,2TRUF@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons hrcA - - ko:K03705 - - - - ko00000,ko03000 - - - HrcA,HrcA_DNA-bdg k141_9528_1 42565.FP66_11335 2.27e-132 393.0 COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,1RNHR@1236|Gammaproteobacteria,1XJV9@135619|Oceanospirillales 135619|Oceanospirillales P receptor - - - ko:K16089 - - - - ko00000,ko02000 1.B.14.1,1.B.14.10 - - Plug,TonB_dep_Rec k141_2405_1 1294265.JCM21738_2660 2.2e-29 105.0 29SHJ@1|root,30DNM@2|Bacteria,1UBGF@1239|Firmicutes,4IMV6@91061|Bacilli,1ZKWQ@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_2405_2 1294265.JCM21738_2659 2.74e-35 132.0 COG0559@1|root,COG4177@1|root,COG0559@2|Bacteria,COG4177@2|Bacteria,1TPMZ@1239|Firmicutes,4HBB8@91061|Bacilli,1ZBKN@1386|Bacillus 91061|Bacilli E Belongs to the binding-protein-dependent transport system permease family - - - ko:K01998,ko:K11961 ko02010,ko02024,map02010,map02024 M00237,M00323 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4,3.A.1.4.4,3.A.1.4.5 - - BPD_transp_2 k141_11906_2 218284.CCDN010000012_gene4445 2.06e-67 219.0 COG2812@1|root,COG2812@2|Bacteria,1TPS9@1239|Firmicutes,4HAUE@91061|Bacilli,1ZB2M@1386|Bacillus 91061|Bacilli L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity dnaX GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNA_pol3_gamma3 k141_16659_2 218284.CCDN010000001_gene1196 5.4e-20 85.1 29PIZ@1|root,30AH4@2|Bacteria,1VJKE@1239|Firmicutes,4HI1K@91061|Bacilli,1ZDJM@1386|Bacillus 91061|Bacilli - - - - 3.4.24.89 ko:K20109 - - - - ko00000,ko01000,ko01002 - - - ATLF k141_17852_1 1307436.PBF_24718 9.09e-38 132.0 2CDA7@1|root,333AV@2|Bacteria,1W3S2@1239|Firmicutes,4I1MP@91061|Bacilli,1ZJ8X@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_33314_1 500635.MITSMUL_05554 4.38e-26 107.0 COG0020@1|root,COG0020@2|Bacteria,1TQTS@1239|Firmicutes,4H2P6@909932|Negativicutes 909932|Negativicutes H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids uppS - 2.5.1.31 ko:K00806 ko00900,ko01110,map00900,map01110 - R06447 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 - - - Prenyltransf k141_13106_2 383372.Rcas_3794 2.33e-15 73.6 2E3MN@1|root,33PAQ@2|Bacteria,2G91W@200795|Chloroflexi,377MD@32061|Chloroflexia 32061|Chloroflexia - - - - - - - - - - - - - - - k141_28565_1 218284.CCDN010000004_gene3055 5.08e-111 328.0 COG4134@1|root,COG4134@2|Bacteria,1TR3G@1239|Firmicutes,4HAW1@91061|Bacilli,1ZD00@1386|Bacillus 91061|Bacilli S Bacterial extracellular solute-binding protein - - - ko:K02055 ko02024,map02024 M00193 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11 - - SBP_bac_8 k141_30929_1 1169144.KB910961_gene4077 2.92e-25 103.0 29SIS@1|root,30DPX@2|Bacteria,1UBIE@1239|Firmicutes,4IMXY@91061|Bacilli,1ZM69@1386|Bacillus 91061|Bacilli S Beta-lactamase enzyme family - - - - - - - - - - - - Beta-lactamase2 k141_30929_2 315730.BcerKBAB4_3108 9.57e-07 49.7 COG0491@1|root,COG0491@2|Bacteria,1TSM4@1239|Firmicutes,4HBZ2@91061|Bacilli,1ZDRZ@1386|Bacillus 91061|Bacilli S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B k141_4787_1 1219065.VPR01S_02_00890 1.52e-48 162.0 COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,1RR68@1236|Gammaproteobacteria,1XSSR@135623|Vibrionales 135623|Vibrionales H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate moaA GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.22 ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09394 RC03420 ko00000,ko00001,ko01000 - - - Fer4_12,Mob_synth_C,Radical_SAM k141_4787_2 1116375.VEJY3_10895 4.7e-183 511.0 COG0391@1|root,COG0391@2|Bacteria,1NW3K@1224|Proteobacteria,1RQP9@1236|Gammaproteobacteria,1XUN3@135623|Vibrionales 135623|Vibrionales S Required for morphogenesis under gluconeogenic growth conditions ybhK - - - - - - - - - - - UPF0052 k141_13107_2 218284.CCDN010000001_gene614 1.77e-49 171.0 COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,4HB0C@91061|Bacilli,1ZD5J@1386|Bacillus 91061|Bacilli NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB pilB - - ko:K02243,ko:K02652 - M00429 - - ko00000,ko00002,ko02035,ko02044 3.A.14.1,3.A.15.2 - - T2SSE,T2SSE_N k141_2406_1 218284.CCDN010000001_gene1275 8.59e-108 316.0 COG0671@1|root,COG0671@2|Bacteria,1VF2U@1239|Firmicutes,4HNXR@91061|Bacilli,1ZIEP@1386|Bacillus 91061|Bacilli I COG0671 Membrane-associated phospholipid phosphatase pap2c - 3.6.1.27 ko:K19302 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - PAP2 k141_4788_1 218284.CCDN010000001_gene1425 4.07e-109 337.0 COG4581@1|root,COG4581@2|Bacteria,1TRYX@1239|Firmicutes,4HU79@91061|Bacilli,1ZE6K@1386|Bacillus 91061|Bacilli L COG0513 Superfamily II DNA and RNA helicases - - 3.6.4.13 ko:K17675 - - - - ko00000,ko01000,ko03029 - - - Helicase_C k141_15492_2 218284.CCDN010000001_gene275 2e-61 199.0 COG1473@1|root,COG1473@2|Bacteria,1TQ7R@1239|Firmicutes,4HB6M@91061|Bacilli,1ZB9M@1386|Bacillus 91061|Bacilli S amidohydrolase amhX - - ko:K14665 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 k141_3600_1 1453501.JELR01000005_gene1574 4.57e-144 413.0 COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,1RM9E@1236|Gammaproteobacteria,4655Q@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the ABC transporter superfamily ugpC - - ko:K10112,ko:K10195 ko02010,map02010 M00194,M00196,M00197,M00200,M00201,M00202,M00206,M00207,M00491,M00602,M00605,M00606 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.11 - - ABC_tran,TOBE_2 k141_5978_1 1128421.JAGA01000003_gene3011 1.28e-56 192.0 COG1249@1|root,COG1249@2|Bacteria,2NNTI@2323|unclassified Bacteria 2|Bacteria C Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain lpdA GO:0000166,GO:0003674,GO:0003824,GO:0004148,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0009987,GO:0015036,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0016667,GO:0016668,GO:0019725,GO:0019899,GO:0032991,GO:0035375,GO:0036094,GO:0040007,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045254,GO:0045454,GO:0048037,GO:0050660,GO:0050662,GO:0050789,GO:0050794,GO:0051287,GO:0055114,GO:0065007,GO:0065008,GO:0070404,GO:0071944,GO:0097159,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyr_redox_2,Pyr_redox_dim k141_29_1 443144.GM21_3255 4.66e-50 163.0 COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,42TNB@68525|delta/epsilon subdivisions,2WQIG@28221|Deltaproteobacteria 28221|Deltaproteobacteria O Peptidyl-prolyl cis-trans fbp - 5.2.1.8 ko:K01802,ko:K03772 - - - - ko00000,ko01000,ko03110 - - - FKBP_C k141_32115_1 218284.CCDN010000001_gene639 6.26e-55 179.0 COG0077@1|root,COG0077@2|Bacteria,1TPDN@1239|Firmicutes,4HA96@91061|Bacilli,1ZAVW@1386|Bacillus 91061|Bacilli E Prephenate dehydratase pheA GO:0003674,GO:0003824,GO:0004664,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0019438,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 4.2.1.51 ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024 R00691,R01373 RC00360 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU27900 ACT,PDT k141_32115_2 218284.CCDN010000001_gene640 1.03e-98 290.0 COG1827@1|root,COG1827@2|Bacteria,1V6EY@1239|Firmicutes,4HGYB@91061|Bacilli,1ZGFK@1386|Bacillus 91061|Bacilli S small molecule binding protein (contains 3H domain) yrxA - - ko:K07105 - - - - ko00000 - - - 3H,HTH_11 k141_28568_1 218284.CCDN010000001_gene1749 3.06e-89 290.0 COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1TPYV@1239|Firmicutes,4HBER@91061|Bacilli,1ZBGN@1386|Bacillus 91061|Bacilli E Methionine synthase metH - 2.1.1.13 ko:K00548 ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230 M00017 R00946,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans k141_10713_1 1042377.AFPJ01000008_gene2006 9.24e-140 399.0 2CHK1@1|root,2ZBVE@2|Bacteria,1NYW8@1224|Proteobacteria,1SPYQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Red chlorophyll catabolite reductase (RCC reductase) - - - - - - - - - - - - RCC_reductase k141_10723_3 1279017.AQYJ01000027_gene1612 4.58e-66 204.0 2DP15@1|root,3303T@2|Bacteria,1N7NN@1224|Proteobacteria,1S90P@1236|Gammaproteobacteria,468AH@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF4426) PP5099 - - - - - - - - - - - DUF4426 k141_10723_4 1453501.JELR01000002_gene981 1.05e-119 344.0 COG0500@1|root,COG2226@2|Bacteria,1MVSY@1224|Proteobacteria,1S24V@1236|Gammaproteobacteria,466CD@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Methionine biosynthesis protein MetW metW - - - - - - - - - - - MetW k141_10723_5 1453501.JELR01000002_gene982 2.26e-243 674.0 COG2021@1|root,COG2021@2|Bacteria,1MVJV@1224|Proteobacteria,1RQ2N@1236|Gammaproteobacteria,465EC@72275|Alteromonadaceae 1236|Gammaproteobacteria E Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine metX GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 ko:K00641 ko00270,ko01100,ko01130,map00270,map01100,map01130 - R01776 RC00004,RC00041 ko00000,ko00001,ko01000 - - - Abhydrolase_1 k141_17887_1 1279017.AQYJ01000025_gene702 5.36e-171 514.0 COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,1RPC6@1236|Gammaproteobacteria,46518@72275|Alteromonadaceae 1236|Gammaproteobacteria L UvrD-like helicase C-terminal domain addA - - - - - - - - - - - PDDEXK_1,UvrD-helicase,UvrD_C k141_2416_1 218284.CCDN010000001_gene1750 1.57e-131 390.0 COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,1TPYV@1239|Firmicutes,4HAB5@91061|Bacilli,1ZBGC@1386|Bacillus 91061|Bacilli E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine yitJ - 1.5.1.20,2.1.1.10 ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 M00377 R00650,R01224,R07168 RC00003,RC00035,RC00081 ko00000,ko00001,ko00002,ko01000 - - - MTHFR,S-methyl_trans k141_13138_1 1382356.JQMP01000003_gene2158 7.57e-59 198.0 COG0696@1|root,COG0696@2|Bacteria,2G7GD@200795|Chloroflexi,27Y1N@189775|Thermomicrobia 189775|Thermomicrobia F Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate gpmI - 5.4.2.12 ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000 - - - Metalloenzyme,iPGM_N k141_16672_1 223926.28809860 1.76e-145 412.0 COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,1RNUF@1236|Gammaproteobacteria,1XT9N@135623|Vibrionales 135623|Vibrionales P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system pstB2 GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015114,GO:0015318,GO:0015399,GO:0015405,GO:0015415,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0035435,GO:0042623,GO:0042626,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0098660,GO:0098661,GO:0099133 3.6.3.27 ko:K02036 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 - - ABC_tran k141_22798_4 223926.28807635 3.05e-176 490.0 COG0220@1|root,COG0220@2|Bacteria,1MUWJ@1224|Proteobacteria,1RMFG@1236|Gammaproteobacteria,1XUSW@135623|Vibrionales 135623|Vibrionales J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA trmB GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 ko:K03439 - - - - ko00000,ko01000,ko03016 - - - Methyltransf_4 k141_22798_5 1116375.VEJY3_13500 1.52e-239 659.0 COG1041@1|root,COG1041@2|Bacteria,1N1XP@1224|Proteobacteria,1S9QB@1236|Gammaproteobacteria,1XV2T@135623|Vibrionales 135623|Vibrionales L Putative RNA methylase family UPF0020 - - - - - - - - - - - - UPF0020 k141_22798_6 1116375.VEJY3_13495 1.93e-134 385.0 COG2066@1|root,COG2066@2|Bacteria,1MWB5@1224|Proteobacteria,1RMY9@1236|Gammaproteobacteria,1XUUJ@135623|Vibrionales 135623|Vibrionales E Belongs to the glutaminase family glsA GO:0003674,GO:0003824,GO:0004359,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006543,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009064,GO:0009065,GO:0009084,GO:0009987,GO:0016053,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 3.5.1.2 ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 - R00256,R01579 RC00010,RC02798 ko00000,ko00001,ko01000 - - - Glutaminase k141_10893_1 479433.Caci_7018 1.48e-141 415.0 COG1073@1|root,COG1765@1|root,COG1073@2|Bacteria,COG1765@2|Bacteria,2GKCA@201174|Actinobacteria 201174|Actinobacteria O Hydrolases of the alpha beta superfamily - - - ko:K06889,ko:K07397 - - - - ko00000 - - - Hydrolase_4,OsmC k141_10893_2 877455.Metbo_0564 1.52e-39 146.0 COG0075@1|root,arCOG00082@2157|Archaea,2XTWU@28890|Euryarchaeota,23NPQ@183925|Methanobacteria 183925|Methanobacteria E Aminotransferase - - - - - - - - - - - - Aminotran_5 k141_37031_1 1328313.DS2_07098 7.9e-132 394.0 COG2273@1|root,COG2273@2|Bacteria,1NFHX@1224|Proteobacteria,1RRPK@1236|Gammaproteobacteria,464WR@72275|Alteromonadaceae 1236|Gammaproteobacteria G Glycosyl hydrolases family 16 bglA - - - - - - - - - - - CBM_6,DUF5011,Glyco_hydro_16,Malectin k141_23983_1 218284.CCDN010000001_gene983 1.79e-191 536.0 COG3426@1|root,COG3426@2|Bacteria,1TPKE@1239|Firmicutes,4H9QV@91061|Bacilli,1ZC7E@1386|Bacillus 91061|Bacilli C Belongs to the acetokinase family buk - 2.7.2.7 ko:K00929 ko00650,ko01100,map00650,map01100 - R01688 RC00002,RC00043 ko00000,ko00001,ko01000 - - - Acetate_kinase k141_22799_1 218284.CCDN010000002_gene2058 8.84e-54 174.0 COG1573@1|root,COG1573@2|Bacteria,1V4M9@1239|Firmicutes,4HHJN@91061|Bacilli,1ZFWW@1386|Bacillus 91061|Bacilli L Uracil DNA glycosylase superfamily ung2 - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG k141_22799_2 218284.CCDN010000002_gene2057 2.16e-11 60.5 COG3871@1|root,COG3871@2|Bacteria,1V6MX@1239|Firmicutes,4HIYZ@91061|Bacilli,1ZH2Z@1386|Bacillus 91061|Bacilli S general stress protein ydaG - - - - - - - - - - - Putative_PNPOx,Pyrid_ox_like k141_31190_8 1280001.BAOA01000070_gene2868 4.7e-167 470.0 COG1116@1|root,COG1116@2|Bacteria,1MUDV@1224|Proteobacteria,1RNEH@1236|Gammaproteobacteria,1XU23@135623|Vibrionales 135623|Vibrionales P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component - - - ko:K15578 ko00910,ko02010,map00910,map02010 M00438 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.16.1 - - ABC_tran k141_16888_1 575540.Isop_0439 9.48e-53 173.0 COG0479@1|root,COG0479@2|Bacteria,2IX7J@203682|Planctomycetes 203682|Planctomycetes C TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein sdhB - 1.3.5.1,1.3.5.4 ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - Fer2_3,Fer4_7,Fer4_8 k141_16888_2 391625.PPSIR1_20474 3.82e-33 127.0 COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,42M81@68525|delta/epsilon subdivisions,2WIJ5@28221|Deltaproteobacteria,2Z30R@29|Myxococcales 28221|Deltaproteobacteria C fumarate reductase, flavoprotein subunit frdA - 1.3.5.1,1.3.5.4 ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C k141_37053_1 1131451.O1K_03101 2.38e-40 152.0 COG2937@1|root,COG2937@2|Bacteria,1MWZ6@1224|Proteobacteria,1RM7K@1236|Gammaproteobacteria,1X4M7@135614|Xanthomonadales 135614|Xanthomonadales I Belongs to the GPAT DAPAT family plsB - 2.3.1.15 ko:K00631 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase k141_25219_1 634956.Geoth_1712 3.26e-164 480.0 COG2225@1|root,COG2225@2|Bacteria,1UA0Z@1239|Firmicutes,4HBPG@91061|Bacilli,1WF7P@129337|Geobacillus 91061|Bacilli H Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA glcB - 2.3.3.9 ko:K01638 ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200 M00012 R00472 RC00004,RC00308,RC02747 ko00000,ko00001,ko00002,ko01000 - - - Malate_synthase k141_10921_1 1116375.VEJY3_00175 2.67e-181 535.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1XSSQ@135623|Vibrionales 135623|Vibrionales V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K18138 ko01501,ko01503,map01501,map01503 M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2 - - ACR_tran k141_22829_1 998674.ATTE01000001_gene593 1.92e-20 95.9 28IAG@1|root,2Z8D2@2|Bacteria,1P5EH@1224|Proteobacteria,1RYCA@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - DUF4129 k141_27523_1 290398.Csal_1761 2.92e-104 313.0 COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,1RMVW@1236|Gammaproteobacteria,1XI8P@135619|Oceanospirillales 135619|Oceanospirillales M Belongs to the UDP-glucose GDP-mannose dehydrogenase family - - 1.1.1.22 ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 M00014,M00129,M00361,M00362 R00286 RC00291 ko00000,ko00001,ko00002,ko01000 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N k141_28836_1 1408424.JHYI01000027_gene4587 6.85e-68 215.0 COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4HF58@91061|Bacilli,1ZCPC@1386|Bacillus 91061|Bacilli P N-terminal TM domain of oligopeptide transport permease C - - - ko:K15586 ko02010,map02010 M00440 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1,OppC_N k141_26503_1 1220589.CD32_09575 3.26e-50 179.0 COG3509@1|root,COG5184@1|root,COG3509@2|Bacteria,COG5184@2|Bacteria,1UZP5@1239|Firmicutes,4HAWI@91061|Bacilli 91061|Bacilli Q Esterase PHB depolymerase - - - - - - - - - - - - CHB_HEX_C_1,Esterase_phd k141_8568_1 926550.CLDAP_38550 6.59e-12 70.9 COG0747@1|root,COG0747@2|Bacteria,2G5NC@200795|Chloroflexi 200795|Chloroflexi E PFAM extracellular solute-binding protein, family 5 - - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 k141_33506_1 1294265.JCM21738_3202 1.34e-63 203.0 COG2206@1|root,COG2206@2|Bacteria,1TR95@1239|Firmicutes,4HB8S@91061|Bacilli,1ZCD6@1386|Bacillus 91061|Bacilli T HD domain M1-161 - - - - - - - - - - - HD,HD_5 k141_33506_2 1294265.JCM21738_3203 1.65e-208 587.0 COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,4HAHY@91061|Bacilli,1ZB8F@1386|Bacillus 91061|Bacilli L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrA - 5.99.1.3 ko:K02469 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseA_C,DNA_topoisoIV k141_3870_1 441769.ABFU01000058_gene768 3.65e-123 359.0 COG4213@1|root,COG4213@2|Bacteria,1TR3Q@1239|Firmicutes,4HDEY@91061|Bacilli,1ZBP4@1386|Bacillus 91061|Bacilli G ABC transporter - - - ko:K10543,ko:K10546 ko02010,map02010 M00215,M00216 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.4,3.A.1.2.5 - - Peripla_BP_4 k141_12188_1 1042377.AFPJ01000004_gene406 1.56e-178 523.0 COG1629@1|root,COG4771@2|Bacteria,1MUWN@1224|Proteobacteria,1RN1E@1236|Gammaproteobacteria,464FG@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec k141_9716_1 1294265.JCM21738_3960 1.01e-104 314.0 COG0658@1|root,COG0658@2|Bacteria,1VHTG@1239|Firmicutes,4ISGH@91061|Bacilli 91061|Bacilli S the current gene model (or a revised gene model) may contain a frame shift - - - ko:K02238 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - Competence,DUF4131 k141_26504_2 391615.ABSJ01000037_gene889 4.73e-05 44.3 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RV50@1236|Gammaproteobacteria,1J5EY@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria I Belongs to the thiolase family fadA - 2.3.1.16,2.3.1.9 ko:K00626,ko:K00632 ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00087,M00088,M00095,M00113,M00373,M00374,M00375 R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095 RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N k141_10922_1 665959.HMPREF1013_02337 1.76e-99 308.0 COG1480@1|root,COG1480@2|Bacteria,1TR1A@1239|Firmicutes,4HAEZ@91061|Bacilli,1ZANS@1386|Bacillus 91061|Bacilli S membrane-associated HD superfamily hydrolase yqfF - - ko:K07037 - - - - ko00000 - - - 7TM-7TMR_HD,7TMR-HDED,HD k141_16890_1 218284.CCDN010000010_gene4394 6.77e-176 512.0 COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HACY@91061|Bacilli,1ZB4C@1386|Bacillus 91061|Bacilli O Belongs to the ClpA ClpB family clpC GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 - ko:K03696 ko01100,map01100 - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N,UVR k141_9717_1 218284.CCDN010000001_gene1914 5.14e-93 277.0 COG1684@1|root,COG1684@2|Bacteria,1TRB2@1239|Firmicutes,4HA2E@91061|Bacilli,1ZBJF@1386|Bacillus 91061|Bacilli N Flagellar biosynthetic protein FliR fliR - - ko:K02421 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - Bac_export_1 k141_34709_1 218284.CCDN010000002_gene1987 7.65e-151 425.0 COG0047@1|root,COG0047@2|Bacteria,1TP1B@1239|Firmicutes,4HAKZ@91061|Bacilli,1ZB9C@1386|Bacillus 91061|Bacilli F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL purQ GO:0003674,GO:0003824,GO:0004642,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - GATase_5 k141_24003_1 1348635.BBJY01000003_gene3767 1.09e-174 501.0 COG0591@1|root,COG0591@2|Bacteria,1MW6E@1224|Proteobacteria,1RXYK@1236|Gammaproteobacteria,1XSDY@135623|Vibrionales 135623|Vibrionales E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - - - - - - - - - - SSF k141_24003_2 1348635.BBJY01000003_gene3766 6.37e-270 747.0 COG1904@1|root,COG1904@2|Bacteria,1MVRI@1224|Proteobacteria,1RMRR@1236|Gammaproteobacteria,1XTDU@135623|Vibrionales 135623|Vibrionales G glucuronate isomerase activity uxaC - 5.3.1.12 ko:K01812 ko00040,ko01100,map00040,map01100 M00061,M00631 R01482,R01983 RC00376 ko00000,ko00001,ko00002,ko01000 - - - UxaC k141_24003_3 1348635.BBJY01000003_gene3765 0.0 1223.0 28HPB@1|root,2Z7XC@2|Bacteria,1MVUK@1224|Proteobacteria,1RQN9@1236|Gammaproteobacteria,1XVXN@135623|Vibrionales 135623|Vibrionales E Alginate lyase - - - - - - - - - - - - Alginate_lyase,Hepar_II_III k141_24003_4 1348635.BBJY01000003_gene3764 0.0 1287.0 COG5360@1|root,COG5360@2|Bacteria,1QUCU@1224|Proteobacteria,1T1TM@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Heparinase II/III-like protein - - 4.2.2.26 ko:K20525 - - - - ko00000,ko01000 - - - Alginate_lyase,Hepar_II_III k141_3872_1 1340434.AXVA01000031_gene2840 5.94e-06 46.2 2DIA4@1|root,302HW@2|Bacteria,1U5Y3@1239|Firmicutes,4IM9X@91061|Bacilli,1ZJJZ@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_13364_2 1453501.JELR01000001_gene1956 8.52e-36 134.0 COG0460@1|root,COG0460@2|Bacteria,1MUDC@1224|Proteobacteria,1RPEU@1236|Gammaproteobacteria,463Y5@72275|Alteromonadaceae 1236|Gammaproteobacteria E homoserine dehydrogenase hom - 1.1.1.3,2.7.2.4 ko:K00003,ko:K12524 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00017,M00018,M00526,M00527 R00480,R01773,R01775 RC00002,RC00043,RC00087 ko00000,ko00001,ko00002,ko01000 - - - ACT,Homoserine_dh,NAD_binding_3 k141_33507_1 218284.CCDN010000002_gene2350 7.51e-73 221.0 2FEGU@1|root,346GD@2|Bacteria,1W0AT@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - - k141_8569_1 1116375.VEJY3_04940 3.79e-104 303.0 COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,1S8RG@1236|Gammaproteobacteria,1XV6J@135623|Vibrionales 135623|Vibrionales M Belongs to the ompA family pal - - ko:K03640 - - - - ko00000,ko02000 2.C.1.2 - - OmpA k141_9718_2 198467.NP92_14590 5.88e-32 117.0 2BZV8@1|root,30HHG@2|Bacteria,1V68P@1239|Firmicutes,4HHRU@91061|Bacilli 91061|Bacilli S Replication-relaxation - - - - - - - - - - - - Replic_Relax k141_16892_1 1294265.JCM21738_4492 1.6e-49 158.0 29S3B@1|root,30D7U@2|Bacteria,1UAYQ@1239|Firmicutes,4IMBN@91061|Bacilli,1ZJR2@1386|Bacillus 91061|Bacilli S Iron-sulphur cluster biosynthesis - - - - - - - - - - - - Fe-S_biosyn k141_18148_2 1279017.AQYJ01000028_gene2519 2.35e-90 272.0 COG1462@1|root,COG1462@2|Bacteria,1MVZM@1224|Proteobacteria,1RQ5F@1236|Gammaproteobacteria,466QU@72275|Alteromonadaceae 1236|Gammaproteobacteria M Curli production assembly/transport component CsgG csgG GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0019867,GO:0022610,GO:0030288,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0033036,GO:0042597,GO:0042710,GO:0042802,GO:0042886,GO:0044010,GO:0044425,GO:0044462,GO:0044464,GO:0044764,GO:0045184,GO:0051179,GO:0051234,GO:0051704,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098552 - ko:K06214 - - - - ko00000,ko02044 - - - CsgG k141_26506_1 1294265.JCM21738_2797 8e-137 405.0 COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,1TQ33@1239|Firmicutes,4HAI2@91061|Bacilli,1ZB3A@1386|Bacillus 91061|Bacilli L COG1796 DNA polymerase IV (family X) polX - - ko:K02347 - - - - ko00000,ko03400 - - - DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8,PHP k141_25220_1 218284.CCDN010000002_gene2034 3.96e-87 267.0 COG1914@1|root,COG1914@2|Bacteria,1TP0Q@1239|Firmicutes,4HAYE@91061|Bacilli,1ZC68@1386|Bacillus 91061|Bacilli P COG1914 Mn2 and Fe2 transporters of the NRAMP family ycsG - - - - - - - - - - - Nramp k141_34710_1 218284.CCDN010000002_gene2737 5.11e-98 296.0 COG0019@1|root,COG0019@2|Bacteria,1TPE9@1239|Firmicutes,4H9XW@91061|Bacilli,1ZD43@1386|Bacillus 91061|Bacilli E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine lysA - 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N,Orn_DAP_Arg_deC k141_3873_1 1415755.JQLV01000001_gene3523 9.07e-57 187.0 COG0687@1|root,COG0687@2|Bacteria,1MW93@1224|Proteobacteria,1RM81@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Spermidine putrescine-binding periplasmic protein - - - ko:K02055 ko02024,map02024 M00193 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11 - - SBP_bac_6,SBP_bac_8 k141_3873_2 42256.RradSPS_1848 1.36e-12 67.8 COG0523@1|root,COG0523@2|Bacteria,2GKDR@201174|Actinobacteria,4CQ83@84995|Rubrobacteria 84995|Rubrobacteria S Cobalamin synthesis protein cobW C-terminal domain - - - - - - - - - - - - CobW_C,cobW k141_26507_1 1294265.JCM21738_3338 1.49e-56 181.0 COG4129@1|root,COG4129@2|Bacteria,1TPVH@1239|Firmicutes,4HAEG@91061|Bacilli,1ZCJA@1386|Bacillus 91061|Bacilli S Membrane ygaE - - - - - - - - - - - ArAE_1 k141_22834_1 218284.CCDN010000001_gene765 4.17e-82 249.0 COG2384@1|root,COG2384@2|Bacteria,1V3I4@1239|Firmicutes,4HHIM@91061|Bacilli,1ZE5B@1386|Bacillus 91061|Bacilli S SAM-dependent methyltransferase trmK GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.217 ko:K06967 - - - - ko00000,ko01000,ko03016 - - - TrmK k141_9719_1 218284.CCDN010000002_gene2835 6.2e-144 411.0 COG1893@1|root,COG1893@2|Bacteria,1TSZ1@1239|Firmicutes,4HB4T@91061|Bacilli,1ZAU6@1386|Bacillus 91061|Bacilli H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid panE1 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 - - - ApbA,ApbA_C k141_8570_1 1144342.PMI40_00381 4.98e-05 49.7 COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,2WCKE@28216|Betaproteobacteria,476EV@75682|Oxalobacteraceae 28216|Betaproteobacteria Q Amidohydrolase family - - - - - - - - - - - - Amidohydro_1 k141_8570_2 575540.Isop_2535 1.37e-29 112.0 COG0580@1|root,COG0580@2|Bacteria,2IZDN@203682|Planctomycetes 203682|Planctomycetes U Belongs to the MIP aquaporin (TC 1.A.8) family - - - ko:K06188 - - - - ko00000,ko02000 1.A.8 - - MIP k141_26508_1 1453501.JELR01000002_gene1309 4.89e-39 134.0 COG1011@1|root,COG1011@2|Bacteria,1NH15@1224|Proteobacteria,1RP27@1236|Gammaproteobacteria,466G1@72275|Alteromonadaceae 1236|Gammaproteobacteria S Haloacid dehalogenase-like hydrolase yrfG GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008477,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016798,GO:0016799,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050483,GO:0050484 3.1.3.5 ko:K20881 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - HAD_2,Hydrolase k141_26508_2 1042377.AFPJ01000028_gene2181 8.3e-35 125.0 COG3714@1|root,COG3714@2|Bacteria,1N6QN@1224|Proteobacteria,1SCQK@1236|Gammaproteobacteria,468R4@72275|Alteromonadaceae 1236|Gammaproteobacteria S YhhN family - - - - - - - - - - - - YhhN k141_28838_1 1453501.JELR01000002_gene874 1.54e-68 211.0 COG3247@1|root,COG3247@2|Bacteria,1RH69@1224|Proteobacteria,1SAIB@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Short repeat of unknown function (DUF308) - - - - - - - - - - - - DUF308 k141_25221_1 218284.CCDN010000006_gene3685 8.32e-87 277.0 COG0653@1|root,COG0653@2|Bacteria,1TPEY@1239|Firmicutes,4HA22@91061|Bacilli,1ZAXF@1386|Bacillus 91061|Bacilli U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW k141_15722_1 1042377.AFPJ01000034_gene2380 1.1e-233 675.0 COG3325@1|root,COG3979@1|root,COG3325@2|Bacteria,COG3979@2|Bacteria,1R3YZ@1224|Proteobacteria,1RY6I@1236|Gammaproteobacteria,46AA7@72275|Alteromonadaceae 1236|Gammaproteobacteria G Chitinase C - - 3.2.1.14,3.2.1.202 ko:K01183,ko:K21606 ko00520,ko01100,map00520,map01100 - R01206,R02334 RC00467 ko00000,ko00001,ko01000 - CBM5,GH18 - CBM_5_12_2,ChiC,Glyco_hydro_18 k141_7395_1 1042377.AFPJ01000055_gene975 6.86e-97 295.0 COG0726@1|root,COG0726@2|Bacteria,1RA45@1224|Proteobacteria,1S2JF@1236|Gammaproteobacteria 1236|Gammaproteobacteria G polysaccharide deacetylase - - - - - - - - - - - - Polysacc_deac_1 k141_7395_2 345073.VC395_0943 7.42e-131 377.0 COG1922@1|root,COG1922@2|Bacteria,1N1HD@1224|Proteobacteria,1RP6P@1236|Gammaproteobacteria,1XST5@135623|Vibrionales 135623|Vibrionales M Belongs to the glycosyltransferase 26 family - - 2.4.1.187 ko:K05946 ko05111,map05111 - - - ko00000,ko00001,ko01000,ko01003 - GT26 - Glyco_tran_WecB k141_33508_1 1294265.JCM21738_5425 6.32e-65 222.0 COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H9SA@91061|Bacilli,1ZAXY@1386|Bacillus 91061|Bacilli M penicillin-binding protein - - 2.4.1.129,3.4.16.4 ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase k141_20381_1 218284.CCDN010000006_gene3660 4.88e-140 405.0 COG0111@1|root,COG0111@2|Bacteria,1V410@1239|Firmicutes,4H9PH@91061|Bacilli,1ZCBB@1386|Bacillus 91061|Bacilli EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family serA - 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C,ACT_4 k141_14517_2 218284.CCDN010000002_gene2060 5.09e-61 201.0 COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,4H9SZ@91061|Bacilli,1ZAX7@1386|Bacillus 91061|Bacilli E Sodium alanine symporter - - - ko:K03310 - - - - ko00000 2.A.25 - - Na_Ala_symp k141_12191_1 1294265.JCM21738_2455 9.55e-273 754.0 COG0661@1|root,COG0661@2|Bacteria,1TPIV@1239|Firmicutes,4HBW3@91061|Bacilli,1ZBPH@1386|Bacillus 91061|Bacilli S ABC1 family ubiB - - ko:K03688 - - - - ko00000 - - - ABC1,APH k141_31191_1 218284.CCDN010000002_gene2274 8.09e-230 646.0 COG0488@1|root,COG0488@2|Bacteria,1TQNA@1239|Firmicutes,4H9VW@91061|Bacilli,1ZBZP@1386|Bacillus 91061|Bacilli S ABC transporter expZ - - ko:K18231 ko02010,map02010 - - - br01600,ko00000,ko00001,ko01504,ko02000 3.A.1.121.1,3.A.1.121.3 - - ABC_tran,ABC_tran_Xtn k141_22837_1 218284.CCDN010000001_gene644 5.6e-108 320.0 COG0379@1|root,COG0379@2|Bacteria,1TP6R@1239|Firmicutes,4H9QG@91061|Bacilli,1ZAR3@1386|Bacillus 91061|Bacilli H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate nadA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 ko:K03517 ko00760,ko01100,map00760,map01100 M00115 R04292 RC01119 ko00000,ko00001,ko00002,ko01000 - - - NadA k141_24006_1 218284.CCDN010000001_gene1813 1.74e-144 419.0 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli,1ZAXK@1386|Bacillus 91061|Bacilli C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively iolA - 1.2.1.18,1.2.1.27 ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 M00013 R00705,R00706,R00922,R00935 RC00004,RC02723,RC02817 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_16894_1 1279017.AQYJ01000025_gene547 1.89e-161 473.0 COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,1RMSR@1236|Gammaproteobacteria,4646K@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the peptidase S41A family prc GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016787,GO:0019538,GO:0023052,GO:0030163,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - BAGE,DUF3340,PDZ,Peptidase_S41 k141_16894_2 1168065.DOK_10672 3.4e-22 90.1 COG1863@1|root,COG1863@2|Bacteria,1MZYJ@1224|Proteobacteria,1S7Z3@1236|Gammaproteobacteria,1J63V@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P Na+/H+ ion antiporter subunit mnhE - - ko:K05569 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - MNHE k141_13367_1 379066.GAU_0813 8.24e-82 262.0 COG0187@1|root,COG0187@2|Bacteria,1ZSP9@142182|Gemmatimonadetes 142182|Gemmatimonadetes L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrB - 5.99.1.3 ko:K02470 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim k141_13367_2 1284352.AOIG01000032_gene331 1.09e-22 97.1 COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,4HAHY@91061|Bacilli,26SZ3@186822|Paenibacillaceae 91061|Bacilli L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrA - 5.99.1.3 ko:K02469 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseA_C,DNA_topoisoIV k141_10927_1 218284.CCDN010000006_gene3582 3.21e-68 210.0 COG5577@1|root,COG5577@2|Bacteria,1UY0E@1239|Firmicutes,4HBCV@91061|Bacilli,1ZRUA@1386|Bacillus 91061|Bacilli M Coat F domain - - - - - - - - - - - - Coat_F k141_10927_2 1385513.N780_18350 9.31e-38 131.0 COG1280@1|root,COG1280@2|Bacteria,1V1Q5@1239|Firmicutes,4HFVQ@91061|Bacilli,2YA7X@289201|Pontibacillus 91061|Bacilli E Amino acid transporter ycgF GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015174,GO:0015181,GO:0015318,GO:0015711,GO:0015802,GO:0015807,GO:0015809,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0034220,GO:0042221,GO:0042493,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902023,GO:1903825,GO:1903826,GO:1905039,GO:1990822 - - - - - - - - - - LysE k141_8572_2 1120979.ATVB01000002_gene217 3.8e-15 78.2 COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,4CYTR@85004|Bifidobacteriales 201174|Actinobacteria KLT PASTA pknL GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 ko:K08884,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PASTA,Pkinase k141_31205_1 1462526.BN990_02249 1.19e-98 287.0 COG3773@1|root,COG3773@2|Bacteria,1V1K8@1239|Firmicutes,4HFTU@91061|Bacilli,4C6PA@84406|Virgibacillus 91061|Bacilli M Cell Wall Hydrolase cwlJ - 3.5.1.28 ko:K01449 - - R04112 RC00064,RC00141 ko00000,ko01000 - - - Hydrolase_2 k141_8589_1 1453501.JELR01000001_gene1849 1.97e-16 77.4 COG1215@1|root,COG1215@2|Bacteria,1MWH9@1224|Proteobacteria,1RPTN@1236|Gammaproteobacteria,4647V@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0463 Glycosyltransferases involved in cell wall biogenesis - - 2.4.1.266 ko:K13693 - - - - ko00000,ko01000,ko01003 - GT81 - - k141_8589_2 1453501.JELR01000001_gene1850 5.59e-96 287.0 COG3769@1|root,COG3769@2|Bacteria,1NFV5@1224|Proteobacteria,1RR9R@1236|Gammaproteobacteria,464IU@72275|Alteromonadaceae 1236|Gammaproteobacteria S Mannosyl-3-phosphoglycerate phosphatase yedP - 2.7.1.31,3.1.3.70 ko:K07026,ko:K15918 ko00051,ko00260,ko00561,ko00630,ko01100,ko01110,ko01130,ko01200,map00051,map00260,map00561,map00630,map01100,map01110,map01130,map01200 M00532 R01514,R05790 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Hydrolase_3,S6PP k141_10938_1 218284.CCDN010000001_gene1872 9.44e-157 442.0 COG0740@1|root,COG0740@2|Bacteria,1TPX2@1239|Firmicutes,4H9XG@91061|Bacilli,1ZBH5@1386|Bacillus 91061|Bacilli OU COG0740 Protease subunit of ATP-dependent Clp proteases tepA - - - - - - - - - - - CLP_protease k141_10938_2 666686.B1NLA3E_06725 3.99e-18 77.4 2DR6C@1|root,33ACS@2|Bacteria,1VM75@1239|Firmicutes,4HR6M@91061|Bacilli,1ZJYN@1386|Bacillus 91061|Bacilli S YlzJ-like protein - - - - - - - - - - - - YlzJ k141_26546_1 42565.FP66_11425 9.67e-70 214.0 COG0605@1|root,COG0605@2|Bacteria,1MV24@1224|Proteobacteria,1SZW5@1236|Gammaproteobacteria,1XP63@135619|Oceanospirillales 135619|Oceanospirillales P Destroys radicals which are normally produced within the cells and which are toxic to biological systems - - 1.15.1.1 ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 - - - ko00000,ko00001,ko01000 - - - Sod_Fe_C,Sod_Fe_N k141_4988_1 218284.CCDN010000001_gene975 5.56e-80 250.0 COG0750@1|root,COG0750@2|Bacteria,1TPIR@1239|Firmicutes,4H9TW@91061|Bacilli,1ZB04@1386|Bacillus 91061|Bacilli M Stage IV sporulation protein B spoIVB - 3.4.21.116 ko:K06399 - - - - ko00000,ko01000,ko01002 - - - PDZ,PDZ_2,Peptidase_S55 k141_29927_2 1042377.AFPJ01000024_gene778 5.12e-44 153.0 COG0438@1|root,COG0438@2|Bacteria,1RKCN@1224|Proteobacteria,1S4CE@1236|Gammaproteobacteria,46BAR@72275|Alteromonadaceae 1236|Gammaproteobacteria M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 k141_3876_2 1121918.ARWE01000001_gene366 5.33e-29 113.0 COG0484@1|root,COG0484@2|Bacteria,1MUZ4@1224|Proteobacteria,42NBY@68525|delta/epsilon subdivisions,2WJV2@28221|Deltaproteobacteria 28221|Deltaproteobacteria O Heat shock protein DnaJ domain protein cbpA - - ko:K05516 - - - - ko00000,ko03036,ko03110 - - - DnaJ,DnaJ_C k141_22866_1 1328313.DS2_07098 2.83e-172 503.0 COG2273@1|root,COG2273@2|Bacteria,1NFHX@1224|Proteobacteria,1RRPK@1236|Gammaproteobacteria,464WR@72275|Alteromonadaceae 1236|Gammaproteobacteria G Glycosyl hydrolases family 16 bglA - - - - - - - - - - - CBM_6,DUF5011,Glyco_hydro_16,Malectin k141_16935_1 1042377.AFPJ01000052_gene1541 9.81e-81 253.0 COG0836@1|root,COG0836@2|Bacteria,1MV39@1224|Proteobacteria,1RNQI@1236|Gammaproteobacteria,4644C@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the mannose-6-phosphate isomerase type 2 family cpsB GO:0000271,GO:0003674,GO:0003824,GO:0004475,GO:0005975,GO:0005976,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0008152,GO:0008905,GO:0008928,GO:0009058,GO:0009059,GO:0009242,GO:0009628,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016772,GO:0016779,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046377,GO:0050896,GO:0070568,GO:0071704,GO:1901135,GO:1901137,GO:1901576 2.7.7.13,5.3.1.8 ko:K00971,ko:K16011 ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025 M00114,M00361,M00362 R00885,R01819 RC00002,RC00376 ko00000,ko00001,ko00002,ko01000 - - iE2348C_1286.E2348C_2191,iEC042_1314.EC042_2286,iECIAI1_1343.ECIAI1_2124,iECO26_1355.ECO26_2960,iECSE_1348.ECSE_2323,iECW_1372.ECW_m2206,iEKO11_1354.EKO11_1746,iEcE24377_1341.EcE24377A_2342,iLF82_1304.LF82_0345,iNRG857_1313.NRG857_10420,iWFL_1372.ECW_m2206 MannoseP_isomer,NTP_transferase k141_35874_1 1408424.JHYI01000019_gene3016 1.22e-05 47.8 COG5582@1|root,COG5582@2|Bacteria,1V5KV@1239|Firmicutes,4HEE0@91061|Bacilli,1ZB4J@1386|Bacillus 91061|Bacilli S Belongs to the UPF0302 family ypiB - - - - - - - - - - - IDEAL,UPF0302 k141_30082_1 1042377.AFPJ01000012_gene1373 4.73e-27 107.0 COG0583@1|root,COG0583@2|Bacteria,1REJ5@1224|Proteobacteria,1S432@1236|Gammaproteobacteria,46CVM@72275|Alteromonadaceae 1236|Gammaproteobacteria K Bacterial regulatory helix-turn-helix protein, lysR family - - - ko:K03566 ko02026,map02026 - - - ko00000,ko00001,ko03000 - - - HTH_1,LysR_substrate k141_6475_1 42565.FP66_07595 6.35e-139 405.0 COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,1RMU9@1236|Gammaproteobacteria,1XIPR@135619|Oceanospirillales 135619|Oceanospirillales U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components ffh - 3.6.5.4 ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko01000,ko02044 3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9 - - SRP54,SRP54_N,SRP_SPB k141_5256_1 997296.PB1_14874 4.77e-83 257.0 COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,4HB0C@91061|Bacilli,1ZBK5@1386|Bacillus 91061|Bacilli NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB comGA - - ko:K02243 - M00429 - - ko00000,ko00002,ko02044 3.A.14.1 - - T2SSE k141_13685_1 1042377.AFPJ01000043_gene865 8.25e-41 141.0 COG0566@1|root,COG0566@2|Bacteria,1MWCM@1224|Proteobacteria,1RN2F@1236|Gammaproteobacteria,4640C@72275|Alteromonadaceae 1236|Gammaproteobacteria J Specifically methylates the ribose of guanosine 2251 in 23S rRNA rlmB GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 ko:K03218 - - - - ko00000,ko01000,ko03009 - - - SpoU_methylase,SpoU_sub_bind k141_26838_2 1236976.JCM16418_2487 8.45e-55 177.0 COG0609@1|root,COG0609@2|Bacteria,1TP13@1239|Firmicutes,4HA75@91061|Bacilli,26QHV@186822|Paenibacillaceae 91061|Bacilli P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily fhuB - - ko:K02015 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - FecCD k141_1603_1 42565.FP66_06670 3.68e-121 345.0 COG0764@1|root,COG0764@2|Bacteria,1MWV8@1224|Proteobacteria,1RP6W@1236|Gammaproteobacteria,1XHB3@135619|Oceanospirillales 135619|Oceanospirillales I Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length fabA - 4.2.1.59,5.3.3.14 ko:K01716 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00083 R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07639 RC00831,RC01078,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FabA k141_1603_2 42565.FP66_06665 3.93e-26 104.0 COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria,1XHMY@135619|Oceanospirillales 135619|Oceanospirillales IQ catalyzes a condensation reaction in fatty acid biosynthesis addition of an acyl acceptor of two carbons from malonyl-ACP fabB - 2.3.1.41 ko:K00647 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt k141_17085_1 218284.CCDN010000004_gene3061 5.05e-204 578.0 COG0018@1|root,COG0018@2|Bacteria,1TPEZ@1239|Firmicutes,4HAR3@91061|Bacilli,1ZBP1@1386|Bacillus 91061|Bacilli J Arginyl-tRNA synthetase argS GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d k141_36033_1 796606.BMMGA3_09640 2.54e-18 84.0 COG0596@1|root,COG0596@2|Bacteria,1V619@1239|Firmicutes,4HCRW@91061|Bacilli,1ZDX1@1386|Bacillus 91061|Bacilli S Serine aminopeptidase, S33 yvaM - 1.11.1.10 ko:K00433 - - - - ko00000,ko01000 - - - Abhydrolase_1,Hydrolase_4 k141_23169_1 218284.CCDN010000008_gene4157 1.69e-68 208.0 COG4824@1|root,COG4824@2|Bacteria,1V3TR@1239|Firmicutes,4HJ0R@91061|Bacilli,1ZHTX@1386|Bacillus 91061|Bacilli S Bacteriophage holin family - - - - - - - - - - - - Phage_holin_4_1 k141_23169_2 441769.ABFU01000052_gene4132 2.19e-23 91.7 2EH05@1|root,33AS7@2|Bacteria,1VQFB@1239|Firmicutes,4HS5P@91061|Bacilli,1ZIHY@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_12543_2 1042377.AFPJ01000028_gene2163 8.12e-48 175.0 COG1729@1|root,COG1729@2|Bacteria,1MX82@1224|Proteobacteria,1T32S@1236|Gammaproteobacteria,465Q0@72275|Alteromonadaceae 1236|Gammaproteobacteria O protein conserved in bacteria - - - - - - - - - - - - TPR_16,TPR_6,TPR_8,YfiO k141_19490_1 1026882.MAMP_02673 5.74e-08 55.5 COG0457@1|root,COG0457@2|Bacteria,1PNM7@1224|Proteobacteria,1RXYT@1236|Gammaproteobacteria,45ZNX@72273|Thiotrichales 72273|Thiotrichales S COG0457 FOG TPR repeat - - - - - - - - - - - - TPR_19 k141_2809_1 218284.CCDN010000008_gene4231 5.68e-149 426.0 COG0476@1|root,COG0476@2|Bacteria,1TQ3U@1239|Firmicutes,4HBGP@91061|Bacilli,1ZBR4@1386|Bacillus 91061|Bacilli H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 moeB GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779 2.7.7.73,2.7.7.80 ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07459 RC00043 ko00000,ko00001,ko01000 - - - ThiF k141_33802_2 218284.CCDN010000001_gene749 1.49e-168 491.0 COG1480@1|root,COG1480@2|Bacteria,1TR1A@1239|Firmicutes,4HAEZ@91061|Bacilli,1ZANS@1386|Bacillus 91061|Bacilli S membrane-associated HD superfamily hydrolase yqfF - - ko:K07037 - - - - ko00000 - - - 7TM-7TMR_HD,7TMR-HDED,HD k141_21864_1 696281.Desru_0473 4.07e-64 205.0 COG2188@1|root,COG2188@2|Bacteria,1UYBW@1239|Firmicutes,24N1N@186801|Clostridia,2626T@186807|Peptococcaceae 186801|Clostridia K UbiC transcription regulator-associated - - - ko:K03710 - - - - ko00000,ko03000 - - - GntR,UTRA k141_615_1 1127673.GLIP_1966 0.0 904.0 COG1629@1|root,COG1629@2|Bacteria,1QTVF@1224|Proteobacteria,1T40W@1236|Gammaproteobacteria,46D7U@72275|Alteromonadaceae 1236|Gammaproteobacteria P TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_17086_1 861299.J421_0408 3.35e-50 164.0 2E3MN@1|root,32NV6@2|Bacteria,1ZV65@142182|Gemmatimonadetes 142182|Gemmatimonadetes S Cytochrome C and Quinol oxidase polypeptide I - - - - - - - - - - - - COX1 k141_27666_1 218284.CCDN010000002_gene2377 3.39e-107 327.0 COG0843@1|root,COG0843@2|Bacteria,1UNPR@1239|Firmicutes,4HDMA@91061|Bacilli,1ZE3W@1386|Bacillus 91061|Bacilli C Cytochrome C and Quinol oxidase polypeptide I - - 1.9.3.1 ko:K02274 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6 - - COX1 k141_28975_1 1051646.VITU9109_08837 2.14e-116 343.0 2DPPV@1|root,332XB@2|Bacteria,1PC3E@1224|Proteobacteria,1TIYC@1236|Gammaproteobacteria,1Y00E@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_28975_2 511062.GU3_05645 3.46e-61 197.0 COG2227@1|root,COG2227@2|Bacteria,1QUAF@1224|Proteobacteria,1S2ZT@1236|Gammaproteobacteria,1Y4NF@135624|Aeromonadales 135624|Aeromonadales H Tellurite resistance protein TehB - - - - - - - - - - - - Methyltransf_23,Methyltransf_25 k141_28975_3 675817.VDA_002793 3.45e-294 836.0 COG1061@1|root,COG1974@1|root,COG3886@1|root,COG1061@2|Bacteria,COG1974@2|Bacteria,COG3886@2|Bacteria,1MV9F@1224|Proteobacteria,1RNAN@1236|Gammaproteobacteria,1XUZY@135623|Vibrionales 135623|Vibrionales L helicase superfamily c-terminal domain - - - - - - - - - - - - DUF3427,Helicase_C,PLDc_2,ResIII k141_36034_1 1453501.JELR01000002_gene1263 1.64e-103 314.0 COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,1RNQM@1236|Gammaproteobacteria,463Y4@72275|Alteromonadaceae 1236|Gammaproteobacteria S Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis ubiB GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016020,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901576,GO:1901661,GO:1901663 - ko:K03688 - - - - ko00000 - - iYL1228.KPN_04331 ABC1 k141_37240_1 1280001.BAOA01000059_gene2273 1.44e-54 171.0 COG0184@1|root,COG0184@2|Bacteria,1MZ2W@1224|Proteobacteria,1S8U6@1236|Gammaproteobacteria,1XXSE@135623|Vibrionales 135623|Vibrionales J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome rpsO GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02956 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S15 k141_37240_2 1116375.VEJY3_12680 3.24e-220 608.0 COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,1RMKP@1236|Gammaproteobacteria,1XSDN@135623|Vibrionales 135623|Vibrionales J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs truB GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 ko:K03177 - - - - ko00000,ko01000,ko03016 - - - TruB-C_2,TruB_C_2,TruB_N k141_37240_3 29495.EA26_17905 1.55e-80 239.0 COG0858@1|root,COG0858@2|Bacteria,1MZPE@1224|Proteobacteria,1S9AF@1236|Gammaproteobacteria,1XWW9@135623|Vibrionales 135623|Vibrionales J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA rbfA GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 - ko:K02834 - - - - ko00000,ko03009 - - - RBFA k141_37240_4 223926.28807454 0.0 1305.0 COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,1RM9X@1236|Gammaproteobacteria,1XSU6@135623|Vibrionales 135623|Vibrionales J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N,IF2_assoc k141_37240_5 1219076.N646_1553 0.0 916.0 COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,1RNQS@1236|Gammaproteobacteria,1XUW8@135623|Vibrionales 135623|Vibrionales K Participates in both transcription termination and antitermination nusA - - ko:K02600 - - - - ko00000,ko03009,ko03021 - - - HHH_5,KH_5,NusA_N k141_37240_6 223926.28807456 4.37e-101 293.0 COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,1S3Y7@1236|Gammaproteobacteria,1XVAA@135623|Vibrionales 135623|Vibrionales J Required for maturation of 30S ribosomal subunits rimP GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - ko:K09748 - - - - ko00000,ko03009 - - - DUF150,DUF150_C k141_10046_1 218284.CCDN010000002_gene2596 1.47e-82 258.0 COG4191@1|root,COG4191@2|Bacteria,1UZ9W@1239|Firmicutes,4HDK2@91061|Bacilli,1ZD85@1386|Bacillus 91061|Bacilli T Histidine kinase kinB - 2.7.13.3 ko:K07697 ko02020,map02020 M00485 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - 5TM-5TMR_LYT,HATPase_c,HisKA k141_1605_2 218284.CCDN010000001_gene1231 4.37e-21 92.0 COG0793@1|root,COG0793@2|Bacteria,1TPBI@1239|Firmicutes,4HAKE@91061|Bacilli,1ZBDE@1386|Bacillus 91061|Bacilli M Belongs to the peptidase S41A family ctpA GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016787,GO:0019538,GO:0023052,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - PDZ,PDZ_2,PG_binding_1,Peptidase_S41 k141_616_1 487316.BBNM01000004_gene574 1.06e-28 112.0 COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,1RQPJ@1236|Gammaproteobacteria,3NJUP@468|Moraxellaceae 1236|Gammaproteobacteria L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group ruvC GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 ko:K01159 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvC k141_616_2 381764.Fnod_1106 8.54e-09 56.2 COG0217@1|root,COG0217@2|Bacteria,2GC36@200918|Thermotogae 200918|Thermotogae K transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - - - - - - - - - - Transcrip_reg k141_30084_1 1500893.JQNB01000001_gene603 5.66e-19 89.4 COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,1RPJS@1236|Gammaproteobacteria,1X4RY@135614|Xanthomonadales 135614|Xanthomonadales NU secretion system protein xcsD - - ko:K02453 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - Secretin,Secretin_N k141_33804_1 1260251.SPISAL_03635 1.14e-87 271.0 COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,1RNIY@1236|Gammaproteobacteria,1WWTN@135613|Chromatiales 135613|Chromatiales E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine - - 2.8.1.7,4.4.1.16 ko:K11717 ko00450,ko01100,map00450,map01100 - R03599,R11528 RC00961,RC01789,RC02313 ko00000,ko00001,ko01000 - - - Aminotran_5,SufE k141_7558_1 279010.BL00982 1.74e-71 227.0 COG2369@1|root,COG2369@2|Bacteria,1V2JT@1239|Firmicutes,4HFSR@91061|Bacilli,1ZIIA@1386|Bacillus 91061|Bacilli S Phage Mu protein F like protein - - - - - - - - - - - - Phage_Mu_F k141_7558_2 320842.Q4ZBZ3_9CAUD 4.07e-36 132.0 4QAJ1@10239|Viruses,4QUNC@35237|dsDNA viruses no RNA stage,4QPE2@28883|Caudovirales,4QM2H@10699|Siphoviridae 10699|Siphoviridae S aminoacyl-tRNA ligase activity - - - - - - - - - - - - - k141_7558_3 665959.HMPREF1013_05317 1.76e-174 492.0 COG4653@1|root,COG4653@2|Bacteria,1UZMZ@1239|Firmicutes,4HBKI@91061|Bacilli,1ZEHH@1386|Bacillus 91061|Bacilli S Phage capsid family - - - - - - - - - - - - Phage_capsid k141_15899_1 1294265.JCM21738_3925 6.88e-138 397.0 28MSG@1|root,2Z80Z@2|Bacteria,1TQD3@1239|Firmicutes,4HB4M@91061|Bacilli,1ZQPW@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2515) - - - - - - - - - - - - DUF2515 k141_23176_1 218284.CCDN010000002_gene2106 7.27e-129 374.0 COG1071@1|root,COG1071@2|Bacteria,1TQDG@1239|Firmicutes,4H9PR@91061|Bacilli,1ZARF@1386|Bacillus 91061|Bacilli C Dehydrogenase E1 component - - 1.2.4.1 ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh k141_2825_2 1396.DJ87_4515 3.18e-34 130.0 COG3227@1|root,COG3227@2|Bacteria,1TP08@1239|Firmicutes,4H9S6@91061|Bacilli,1ZCEP@1386|Bacillus 91061|Bacilli E Peptidase M4 npr GO:0005575,GO:0005576 3.4.24.28 ko:K01400 - - - - ko00000,ko01000,ko01002 - - - FTP,PepSY,Peptidase_M4,Peptidase_M4_C k141_32443_1 1453501.JELR01000002_gene617 4.84e-21 91.3 COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,1RQQV@1236|Gammaproteobacteria,46448@72275|Alteromonadaceae 1236|Gammaproteobacteria MU COG1538 Outer membrane protein tolC - - ko:K12340 ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133 M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko02044 1.B.17,2.A.6.2 - - OEP k141_32443_2 1042377.AFPJ01000024_gene768 2.97e-126 366.0 COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,1RPTA@1236|Gammaproteobacteria,464JQ@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0451 Nucleoside-diphosphate-sugar epimerases capI - 5.1.3.25,5.1.3.6 ko:K08679,ko:K17947 ko00520,ko00523,ko01100,ko01130,map00520,map00523,map01100,map01130 - R01385,R10279 RC00289 ko00000,ko00001,ko01000 - - - Epimerase,GDP_Man_Dehyd k141_31345_1 218284.CCDN010000002_gene2714 6.02e-12 64.3 COG1132@1|root,COG1132@2|Bacteria,1VS01@1239|Firmicutes,4HTGJ@91061|Bacilli,1ZEQ6@1386|Bacillus 91061|Bacilli V ABC transporter transmembrane region - - - - - - - - - - - - ABC_membrane,ABC_tran k141_31345_2 218284.CCDN010000002_gene2714 1.35e-65 214.0 COG1132@1|root,COG1132@2|Bacteria,1VS01@1239|Firmicutes,4HTGJ@91061|Bacilli,1ZEQ6@1386|Bacillus 91061|Bacilli V ABC transporter transmembrane region - - - - - - - - - - - - ABC_membrane,ABC_tran k141_10072_1 218284.CCDN010000008_gene4221 3.32e-66 201.0 COG3118@1|root,COG3118@2|Bacteria,1VEPC@1239|Firmicutes,4HNXE@91061|Bacilli,1ZI6R@1386|Bacillus 91061|Bacilli O Protein of unknown function (DUF2847) ytxJ - - - - - - - - - - - DUF2847 k141_10072_2 218284.CCDN010000008_gene4220 3.05e-55 177.0 COG4980@1|root,COG4980@2|Bacteria,1VFY7@1239|Firmicutes,4HNWV@91061|Bacilli,1ZEKS@1386|Bacillus 91061|Bacilli S COG4980 Gas vesicle protein ytxH - - - - - - - - - - - YtxH k141_18397_1 1123288.SOV_3c07130 7.49e-21 92.8 COG0725@1|root,COG0725@2|Bacteria,1U9U3@1239|Firmicutes,4H30T@909932|Negativicutes 909932|Negativicutes P ABC transporter, periplasmic molybdate-binding protein modA - - ko:K02020 ko02010,map02010 M00189 - - ko00000,ko00001,ko00002,ko02000 3.A.1.8 - - SBP_bac_11 k141_17100_1 1134474.O59_004195 3.37e-41 142.0 COG1247@1|root,COG1247@2|Bacteria,1RDHN@1224|Proteobacteria,1T03S@1236|Gammaproteobacteria,1FIEM@10|Cellvibrio 1236|Gammaproteobacteria M Acetyltransferase (GNAT) domain - - 2.3.1.183 ko:K03823 ko00440,ko01130,map00440,map01130 - R08871,R08938 RC00004,RC00064 ko00000,ko00001,ko01000 - - - Acetyltransf_4 k141_17100_2 1453501.JELR01000001_gene3220 1.14e-179 503.0 COG0625@1|root,COG0625@2|Bacteria,1MUN3@1224|Proteobacteria,1RMF7@1236|Gammaproteobacteria,464IW@72275|Alteromonadaceae 1236|Gammaproteobacteria O Glutathione S-transferase yghU - - ko:K11209 - - - - ko00000,ko01000 - - - GST_C,GST_C_2,GST_N k141_5286_1 1294265.JCM21738_3274 3.74e-165 470.0 COG0477@1|root,COG0477@2|Bacteria,1TQIJ@1239|Firmicutes,4HAM0@91061|Bacilli,1ZCHJ@1386|Bacillus 91061|Bacilli EGP Transporter proP - - - - - - - - - - - MFS_1,Sugar_tr k141_23178_1 1123487.KB892868_gene1187 1.66e-100 306.0 COG0714@1|root,COG0714@2|Bacteria,1MXQ2@1224|Proteobacteria,2W10G@28216|Betaproteobacteria 28216|Betaproteobacteria S ATPase family associated with various cellular activities (AAA) - - - - - - - - - - - - AAA_3 k141_25515_1 926550.CLDAP_19190 1.98e-32 127.0 COG0365@1|root,COG0365@2|Bacteria,2G5KE@200795|Chloroflexi 2|Bacteria I Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA acsA - 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACAS_N,AMP-binding,AMP-binding_C k141_25515_2 596154.Alide2_2122 2.05e-28 117.0 COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2VH2F@28216|Betaproteobacteria,4A9PT@80864|Comamonadaceae 28216|Betaproteobacteria P ATPase, P-type (transporting), HAD superfamily, subfamily IC ctpF - 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - - Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3 k141_33818_1 1453501.JELR01000001_gene2142 2.01e-65 214.0 COG1115@1|root,COG1115@2|Bacteria,1MUI3@1224|Proteobacteria,1RMNF@1236|Gammaproteobacteria,464HE@72275|Alteromonadaceae 1236|Gammaproteobacteria E alanine symporter yaaJ GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03310 - - - - ko00000 2.A.25 - iEcE24377_1341.EcE24377A_0007 Na_Ala_symp k141_33818_2 1279017.AQYJ01000029_gene3647 1.81e-53 175.0 COG3246@1|root,COG3246@2|Bacteria,1MZTP@1224|Proteobacteria,1RRUP@1236|Gammaproteobacteria,466BX@72275|Alteromonadaceae 1236|Gammaproteobacteria S Pfam:Kce - - - - - - - - - - - - BKACE k141_13707_1 1453501.JELR01000002_gene344 1.56e-22 93.2 COG0848@1|root,COG0848@2|Bacteria,1RENY@1224|Proteobacteria,1S3TB@1236|Gammaproteobacteria 1236|Gammaproteobacteria U biopolymer transport protein - - - - - - - - - - - - ExbD k141_13707_2 1279017.AQYJ01000026_gene59 1.27e-21 97.4 COG0810@1|root,COG0810@2|Bacteria,1R65W@1224|Proteobacteria,1S133@1236|Gammaproteobacteria,466F5@72275|Alteromonadaceae 1236|Gammaproteobacteria M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - - - - - - - - - - TonB_C k141_28986_2 218284.CCDN010000005_gene3316 5.61e-99 297.0 COG0491@1|root,COG0491@2|Bacteria,1TT3D@1239|Firmicutes,4HDKE@91061|Bacilli,1ZCQE@1386|Bacillus 91061|Bacilli S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B k141_21880_1 1042377.AFPJ01000052_gene1582 1.01e-121 375.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria,4651V@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec k141_14671_1 935836.JAEL01000035_gene1985 1.48e-170 501.0 COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HACY@91061|Bacilli,1ZB8K@1386|Bacillus 91061|Bacilli O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE clpB GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564 - ko:K03695 ko04213,map04213 - - - ko00000,ko00001,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N k141_7570_1 218284.CCDN010000008_gene4152 6.43e-28 103.0 COG0759@1|root,COG0759@2|Bacteria,1VEIG@1239|Firmicutes,4HPA3@91061|Bacilli,1ZHVV@1386|Bacillus 91061|Bacilli S Could be involved in insertion of integral membrane proteins into the membrane ytjA - - ko:K08998 - - - - ko00000 - - - Haemolytic k141_20645_2 1528106.JRJE01000031_gene3668 9.04e-19 88.6 COG0174@1|root,COG0174@2|Bacteria,1MU6V@1224|Proteobacteria,2TTPD@28211|Alphaproteobacteria,2JQ42@204441|Rhodospirillales 204441|Rhodospirillales E Glutamine synthetase, catalytic domain - - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C k141_5287_1 218284.CCDN010000005_gene3192 2.46e-124 361.0 COG0407@1|root,COG0407@2|Bacteria,1TR8Q@1239|Firmicutes,4HAXT@91061|Bacilli,1ZDGX@1386|Bacillus 91061|Bacilli H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III hemE GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03197,R04972 RC00872 ko00000,ko00001,ko00002,ko01000 - - - URO-D k141_23179_1 324057.Pjdr2_0979 4.39e-83 256.0 COG4214@1|root,COG4214@2|Bacteria,1VU1F@1239|Firmicutes,4HBDM@91061|Bacilli,26RAY@186822|Paenibacillaceae 91061|Bacilli G Belongs to the binding-protein-dependent transport system permease family - - - ko:K10544,ko:K10547 ko02010,map02010 M00215,M00216 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.4,3.A.1.2.5 - - BPD_transp_2 k141_18399_1 1279017.AQYJ01000029_gene3695 1.27e-16 73.6 COG2900@1|root,COG2900@2|Bacteria,1NGFM@1224|Proteobacteria,1SGAM@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Belongs to the SlyX family slyX - - ko:K03745 - - - - ko00000 - - - SlyX k141_25516_1 1283287.KB822582_gene2893 3.56e-105 320.0 COG1757@1|root,COG1757@2|Bacteria,2I8CQ@201174|Actinobacteria 201174|Actinobacteria C Na H antiporter nhaC - - ko:K03315 - - - - ko00000,ko02000 2.A.35 - - Na_H_antiporter k141_19514_1 997296.PB1_00130 6.31e-91 272.0 28KFQ@1|root,2ZA1R@2|Bacteria,1V063@1239|Firmicutes,4HFDF@91061|Bacilli,1ZCCB@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - DUF3794 k141_10074_1 1188252.AJYK01000114_gene1602 2.65e-31 119.0 2DBCW@1|root,2Z8FS@2|Bacteria,1NVNA@1224|Proteobacteria,1S1MI@1236|Gammaproteobacteria,1XYMR@135623|Vibrionales 135623|Vibrionales S Domain of unknown function (DUF4434) - - - - - - - - - - - - DUF4434 k141_10074_2 675814.VIC_001634 4.27e-18 83.2 COG0457@1|root,COG0457@2|Bacteria,1QWBQ@1224|Proteobacteria,1T2T1@1236|Gammaproteobacteria,1XW90@135623|Vibrionales 135623|Vibrionales S Bacteriophage N adsorption protein A C-term - - - ko:K11739 - - - - ko00000 - - - NfrA_C k141_11244_1 218284.CCDN010000007_gene3964 3.24e-129 374.0 COG1879@1|root,COG1879@2|Bacteria,1TSUI@1239|Firmicutes,4HBMV@91061|Bacilli,1ZC6R@1386|Bacillus 91061|Bacilli G Periplasmic binding protein domain rbsB5 - - ko:K02058 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - Peripla_BP_4 k141_2827_1 1487953.JMKF01000050_gene1927 8.51e-71 223.0 COG2040@1|root,COG2040@2|Bacteria,1G1ZI@1117|Cyanobacteria 1117|Cyanobacteria H Homocysteine s-methyltransferase - - - - - - - - - - - - S-methyl_trans k141_8871_2 218284.CCDN010000005_gene3200 2.25e-188 526.0 COG0095@1|root,COG0095@2|Bacteria,1TQ5U@1239|Firmicutes,4H9P6@91061|Bacilli,1ZBIZ@1386|Bacillus 91061|Bacilli H Lipoate-protein ligase lplJ GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0016874,GO:0016879,GO:0016979,GO:0017118,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:0140096,GO:1901564 6.3.1.20 ko:K03800 ko00785,ko01100,map00785,map01100 - R07770,R07771,R11143 RC00043,RC00070,RC00090,RC00992,RC02896 ko00000,ko00001,ko01000 - - - BPL_LplA_LipB,Lip_prot_lig_C k141_7571_1 634956.Geoth_2877 1.73e-09 56.2 2EI26@1|root,33BTM@2|Bacteria,1VQ3U@1239|Firmicutes,4HRAZ@91061|Bacilli,1WGTW@129337|Geobacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_630_2 1279017.AQYJ01000026_gene23 5.65e-193 536.0 COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,1RNSW@1236|Gammaproteobacteria,4649I@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate folD - 1.5.1.5,3.5.4.9 ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R01220,R01655 RC00202,RC00578 ko00000,ko00001,ko00002,ko01000 - - - THF_DHG_CYH,THF_DHG_CYH_C k141_630_3 1123279.ATUS01000006_gene3502 7.3e-43 147.0 COG1187@1|root,COG1187@2|Bacteria,1MU6M@1224|Proteobacteria,1RQA9@1236|Gammaproteobacteria,1J5U8@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Belongs to the pseudouridine synthase RsuA family rsuA - 5.4.99.19 ko:K06183 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 k141_12564_1 218284.CCDN010000004_gene3122 5.11e-66 215.0 COG0415@1|root,COG0415@2|Bacteria,1TQAK@1239|Firmicutes,4HB9K@91061|Bacilli,1ZCI5@1386|Bacillus 91061|Bacilli L Belongs to the DNA photolyase family phrB - 4.1.99.3 ko:K01669 - - - - ko00000,ko01000,ko03400 - - - DNA_photolyase,FAD_binding_7 k141_34962_1 223926.28807961 2.03e-81 243.0 COG0724@1|root,COG0724@2|Bacteria,1N0P8@1224|Proteobacteria,1S987@1236|Gammaproteobacteria,1XWU8@135623|Vibrionales 135623|Vibrionales S COG0724 RNA-binding proteins (RRM domain) - - - - - - - - - - - - RRM_1 k141_34962_2 1116375.VEJY3_14840 1.63e-157 446.0 COG0796@1|root,COG0796@2|Bacteria,1NAI2@1224|Proteobacteria,1RPU9@1236|Gammaproteobacteria,1XTNA@135623|Vibrionales 135623|Vibrionales M Provides the (R)-glutamate required for cell wall biosynthesis murI GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0034645,GO:0036361,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 5.1.1.3 ko:K01776 ko00471,ko01100,map00471,map01100 - R00260 RC00302 ko00000,ko00001,ko01000,ko01011 - - - Asp_Glu_race k141_34962_3 1280001.BAOA01000088_gene3615 0.0 1069.0 COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,1RMFJ@1236|Gammaproteobacteria,1XT6V@135623|Vibrionales 135623|Vibrionales H Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB btuB GO:0003674,GO:0005215 - ko:K16092 - - - - ko00000,ko02000 1.B.14.3 - - Plug,TonB_dep_Rec k141_34962_4 674977.VMC_40880 7.56e-193 539.0 COG2265@1|root,COG2265@2|Bacteria,1MY45@1224|Proteobacteria,1RN2B@1236|Gammaproteobacteria,1XSB1@135623|Vibrionales 135623|Vibrionales J Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA) trmA GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 2.1.1.35 ko:K00557 - - - - ko00000,ko01000,ko03016 - - - tRNA_U5-meth_tr k141_15901_1 42565.FP66_00165 4.32e-157 442.0 COG2857@1|root,COG2857@2|Bacteria,1QFU2@1224|Proteobacteria,1RN4Y@1236|Gammaproteobacteria,1XHE5@135619|Oceanospirillales 135619|Oceanospirillales C Cytochrome c1 petC - - ko:K00413 ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152 - - ko00000,ko00001,ko00002 - - - Cytochrom_C1 k141_11245_1 1219076.N646_3798 1.51e-139 407.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RQ6F@1236|Gammaproteobacteria,1XUU7@135623|Vibrionales 135623|Vibrionales C belongs to the aldehyde dehydrogenase family - - - ko:K15786 ko00260,map00260 - R09805 RC00080 ko00000,ko00001,ko01000 - - - Aldedh k141_31346_1 1042377.AFPJ01000020_gene2059 2.92e-107 335.0 COG0457@1|root,COG0457@2|Bacteria,1MX2U@1224|Proteobacteria,1RPD2@1236|Gammaproteobacteria,464NG@72275|Alteromonadaceae 1236|Gammaproteobacteria C Cytochrome c554 and c-prime - - - - - - - - - - - - Cytochrome_C554,HEAT_2,Paired_CXXCH_1,TPR_16,TPR_19,TPR_20,TPR_8 k141_25800_1 330084.JNYZ01000011_gene7332 4.37e-20 90.5 COG1228@1|root,COG1228@2|Bacteria,2GMUS@201174|Actinobacteria,4E1ST@85010|Pseudonocardiales 201174|Actinobacteria Q Amidohydrolase family - - - - - - - - - - - - Amidohydro_1 k141_25800_2 1177179.A11A3_01365 2.08e-28 107.0 COG2050@1|root,COG2050@2|Bacteria,1RJ5Q@1224|Proteobacteria,1SB58@1236|Gammaproteobacteria,1XPZ0@135619|Oceanospirillales 135619|Oceanospirillales Q Domain of unknown function (DUF4442) - - - - - - - - - - - - DUF4442 k141_35244_2 218284.CCDN010000002_gene2084 3.94e-205 569.0 COG3396@1|root,COG3396@2|Bacteria,1TRTS@1239|Firmicutes,4HAII@91061|Bacilli,1ZC82@1386|Bacillus 91061|Bacilli S Phenylacetic acid catabolic protein paaA - 1.14.13.149 ko:K02609 ko00360,ko01120,map00360,map01120 - R09838 RC02690 ko00000,ko00001,ko01000 - - - PaaA_PaaC k141_29155_1 1453501.JELR01000002_gene911 6.39e-18 82.0 COG1716@1|root,COG3456@1|root,COG1716@2|Bacteria,COG3456@2|Bacteria,1R3R7@1224|Proteobacteria,1RRIU@1236|Gammaproteobacteria,46CUW@72275|Alteromonadaceae 1236|Gammaproteobacteria T Forkhead associated domain - - - ko:K07169,ko:K11894,ko:K11913 ko02025,ko03070,map02025,map03070 - - - ko00000,ko00001,ko02044 3.A.23.1 - - FHA k141_29155_2 1453501.JELR01000002_gene912 3.1e-65 213.0 COG3516@1|root,COG3517@1|root,COG3516@2|Bacteria,COG3517@2|Bacteria,1NAN0@1224|Proteobacteria,1S07D@1236|Gammaproteobacteria,46BEH@72275|Alteromonadaceae 1236|Gammaproteobacteria S Type VI secretion protein, EvpB/VC_A0108, tail sheath - - - ko:K11900 ko02025,map02025 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - T6SS_VipA,VipB k141_7730_2 1121939.L861_20310 2.01e-98 291.0 COG3806@1|root,COG3806@2|Bacteria,1R52I@1224|Proteobacteria,1RNI5@1236|Gammaproteobacteria,1XHQI@135619|Oceanospirillales 135619|Oceanospirillales T COG3806 Anti-sigma factor - - - - - - - - - - - - Cupin_7 k141_9084_1 1279017.AQYJ01000020_gene1207 7.53e-40 147.0 COG0038@1|root,COG0038@2|Bacteria,1MV4K@1224|Proteobacteria,1RQJW@1236|Gammaproteobacteria,465J9@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0038 Chloride channel protein EriC eriC - - ko:K03281 - - - - ko00000 2.A.49 - - Voltage_CLC k141_9084_2 1042377.AFPJ01000032_gene2695 1.23e-79 238.0 COG1981@1|root,COG1981@2|Bacteria,1RHGS@1224|Proteobacteria,1S5XY@1236|Gammaproteobacteria,467HW@72275|Alteromonadaceae 1236|Gammaproteobacteria S membrane - - - ko:K08973 - - - - ko00000 - - - UPF0093 k141_9084_3 1279017.AQYJ01000020_gene1209 8.26e-158 446.0 COG0351@1|root,COG0351@2|Bacteria,1MU9J@1224|Proteobacteria,1RNFP@1236|Gammaproteobacteria,4670A@72275|Alteromonadaceae 1236|Gammaproteobacteria H Phosphomethylpyrimidine kinase thiD - 2.7.1.49,2.7.4.7 ko:K00941 ko00730,ko01100,map00730,map01100 M00127 R03471,R04509 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Phos_pyr_kin k141_27865_2 218284.CCDN010000001_gene706 2.79e-89 271.0 COG0626@1|root,COG0626@2|Bacteria,1TPC7@1239|Firmicutes,4HAFQ@91061|Bacilli,1ZAR9@1386|Bacillus 91061|Bacilli E cystathionine mccB GO:0000096,GO:0000098,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008284,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019752,GO:0042127,GO:0043418,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0048518,GO:0048522,GO:0050667,GO:0050789,GO:0050794,GO:0065007,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 4.4.1.1,4.4.1.2,4.4.1.8 ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017,M00609 R00782,R01001,R01283,R01286,R02408,R04941 RC00056,RC00069,RC00348,RC00382,RC00487,RC00488,RC00710,RC01245,RC02303,RC02814 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU27250 Cys_Met_Meta_PP k141_20807_1 506534.Rhein_2857 8.22e-37 142.0 COG0577@1|root,COG0577@2|Bacteria,1PIKV@1224|Proteobacteria,1SYRG@1236|Gammaproteobacteria 1224|Proteobacteria V ABC-type antimicrobial peptide transport system, permease component - - - - - - - - - - - - FtsX,MacB_PCD k141_16125_1 566466.NOR53_1887 2.25e-92 300.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RWYZ@1236|Gammaproteobacteria,1J9VN@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec k141_27121_1 1042377.AFPJ01000019_gene2535 0.000633 41.6 COG0044@1|root,COG0044@2|Bacteria,1MUPA@1224|Proteobacteria,1RNYU@1236|Gammaproteobacteria,46DC4@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the hydrolytic cleavage of a subset of L- isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation - - - ko:K01305 - - - - ko00000,ko01000,ko01002 - - - Amidohydro_1 k141_18664_1 1294265.JCM21738_1025 4.72e-21 83.6 COG4479@1|root,COG4479@2|Bacteria,1VFI4@1239|Firmicutes,4HR7P@91061|Bacilli,1ZJ7C@1386|Bacillus 91061|Bacilli S Belongs to the UPF0346 family yozE - - - - - - - - - - - YozE_SAM_like k141_18664_2 1196031.ALEG01000005_gene5613 2.3e-61 194.0 2ESB9@1|root,33JW0@2|Bacteria,1VMVV@1239|Firmicutes,4HSTZ@91061|Bacilli,1ZD8X@1386|Bacillus 91061|Bacilli - - yodN - - - - - - - - - - - - k141_17283_1 1453501.JELR01000002_gene1333 1.17e-228 640.0 2BWPY@1|root,2Z8BI@2|Bacteria,1QHHB@1224|Proteobacteria,1RP8D@1236|Gammaproteobacteria,4657P@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_17283_2 1279017.AQYJ01000028_gene2079 5.92e-284 798.0 COG2755@1|root,COG2755@2|Bacteria,1MXTS@1224|Proteobacteria,1RTPH@1236|Gammaproteobacteria,46419@72275|Alteromonadaceae 1236|Gammaproteobacteria E Concanavalin A-like lectin/glucanases superfamily - - - - - - - - - - - - Laminin_G_3 k141_20821_1 218284.CCDN010000006_gene3580 1.03e-114 333.0 COG3403@1|root,COG3403@2|Bacteria,1US5K@1239|Firmicutes,4HD46@91061|Bacilli,1ZQUK@1386|Bacillus 91061|Bacilli G YqcI/YcgG family - - - ko:K09190 - - - - ko00000 - - - YqcI_YcgG k141_11535_1 218284.CCDN010000001_gene1664 9.34e-21 91.7 COG0639@1|root,COG0639@2|Bacteria,1UYWX@1239|Firmicutes,4HEJF@91061|Bacilli,1ZFAS@1386|Bacillus 91061|Bacilli T Calcineurin-like phosphoesterase - - 3.1.3.16 ko:K01090 - - - - ko00000,ko01000 - - - Metallophos k141_11535_2 218284.CCDN010000001_gene1665 1.71e-57 181.0 2B0T9@1|root,31T5P@2|Bacteria,1V9AV@1239|Firmicutes,4HM11@91061|Bacilli,1ZI0C@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - Nuc_deoxyrib_tr k141_19764_1 1403313.AXBR01000022_gene2894 5.31e-22 90.5 2CY4V@1|root,32T3F@2|Bacteria,1VDQ0@1239|Firmicutes,4HKEQ@91061|Bacilli,1ZIB4@1386|Bacillus 91061|Bacilli S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) - - - - - - - - - - - - Spore_YhcN_YlaJ k141_13999_1 279010.BL00983 5.51e-44 156.0 2DB9U@1|root,2Z7Z6@2|Bacteria,1TR67@1239|Firmicutes,4HCTZ@91061|Bacilli,1ZEZR@1386|Bacillus 91061|Bacilli S Phage portal protein, SPP1 Gp6-like - - - - - - - - - - - - Phage_prot_Gp6 k141_13999_2 10724.GP7_BPSPP 3.37e-14 73.2 4QC5Z@10239|Viruses,4QUNP@35237|dsDNA viruses no RNA stage,4QPGX@28883|Caudovirales,4QKMB@10699|Siphoviridae 10699|Siphoviridae S Phage Mu protein F like protein - GO:0005575,GO:0019012,GO:0019028,GO:0044423,GO:0046729 - - - - - - - - - - - k141_29174_1 218284.CCDN010000012_gene4445 1.6e-126 377.0 COG2812@1|root,COG2812@2|Bacteria,1TPS9@1239|Firmicutes,4HAUE@91061|Bacilli,1ZB2M@1386|Bacillus 91061|Bacilli L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity dnaX GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNA_pol3_gamma3 k141_29174_2 1034347.CAHJ01000090_gene1647 6.97e-54 170.0 COG0718@1|root,COG0718@2|Bacteria,1VA1S@1239|Firmicutes,4HKH3@91061|Bacilli,1ZGZI@1386|Bacillus 91061|Bacilli S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection yaaK - - ko:K09747 - - - - ko00000 - - - YbaB_DNA_bd k141_23432_2 1279017.AQYJ01000029_gene3323 7.67e-304 835.0 COG1012@1|root,COG1012@2|Bacteria,1MUHV@1224|Proteobacteria,1RNFN@1236|Gammaproteobacteria,465NX@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1012 NAD-dependent aldehyde dehydrogenases mmsA - 1.2.1.18,1.2.1.27 ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 M00013 R00705,R00706,R00922,R00935 RC00004,RC02723,RC02817 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_23432_3 1453501.JELR01000002_gene591 7.29e-36 131.0 COG3047@1|root,COG3047@2|Bacteria,1NUZJ@1224|Proteobacteria,1RRRC@1236|Gammaproteobacteria,467CK@72275|Alteromonadaceae 1236|Gammaproteobacteria M Outer membrane protein W ompW - - ko:K07275 - - - - ko00000 - - - OmpW k141_34021_1 379066.GAU_1307 4.02e-86 277.0 COG2217@1|root,COG2217@2|Bacteria,1ZTC7@142182|Gemmatimonadetes 2|Bacteria P E1-E2 ATPase cadA - 3.6.3.3,3.6.3.5 ko:K01534 - - - - ko00000,ko01000 3.A.3.6 - - E1-E2_ATPase,Hydrolase k141_25803_1 1116375.VEJY3_17586 0.0 1060.0 COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,1RPEM@1236|Gammaproteobacteria,1XUK7@135623|Vibrionales 135623|Vibrionales U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA - - - ko:K03072 ko03060,ko03070,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD-TM1,SecD_SecF,Sec_GG k141_25803_2 1116375.VEJY3_17591 4.51e-188 525.0 COG0341@1|root,COG0341@2|Bacteria,1MY1H@1224|Proteobacteria,1RY1N@1236|Gammaproteobacteria,1XUNI@135623|Vibrionales 135623|Vibrionales U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA - - - ko:K03074 ko03060,ko03070,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD_SecF,Sec_GG k141_25803_3 1116375.VEJY3_17596 3.98e-111 322.0 COG1280@1|root,COG1280@2|Bacteria,1Q4CV@1224|Proteobacteria,1RQV8@1236|Gammaproteobacteria,1XT0S@135623|Vibrionales 135623|Vibrionales E LysE type translocator - - - - - - - - - - - - LysE k141_25803_4 1116375.VEJY3_17601 2.53e-158 446.0 COG1028@1|root,COG1028@2|Bacteria,1MUEV@1224|Proteobacteria,1RNH2@1236|Gammaproteobacteria,1XTP4@135623|Vibrionales 135623|Vibrionales IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) phbB - 1.1.1.36 ko:K00023 ko00630,ko00650,ko01120,ko01200,map00630,map00650,map01120,map01200 M00373 R01779,R01977 RC00103,RC00117 ko00000,ko00001,ko00002,ko01000 - - - adh_short_C2 k141_25803_5 1116375.VEJY3_17606 3.88e-252 696.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RM93@1236|Gammaproteobacteria,1XSMR@135623|Vibrionales 135623|Vibrionales I Belongs to the thiolase family - - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N k141_25803_6 1116375.VEJY3_17611 4.9e-65 199.0 2C668@1|root,32W8B@2|Bacteria,1N0CT@1224|Proteobacteria,1SA1B@1236|Gammaproteobacteria,1XXAJ@135623|Vibrionales 135623|Vibrionales S Phasin protein - - - - - - - - - - - - Phasin_2 k141_25803_7 1116375.VEJY3_17616 0.0 1107.0 COG3243@1|root,COG3243@2|Bacteria,1MU68@1224|Proteobacteria,1RPVQ@1236|Gammaproteobacteria,1XUBI@135623|Vibrionales 135623|Vibrionales I Polyhydroxyalkanoic acid synthase phaC - - ko:K03821 ko00650,map00650 - R04254 RC00004 ko00000,ko00001,ko01000 - - - PhaC_N k141_10364_1 42565.FP66_08005 6.64e-110 320.0 COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,1RMHI@1236|Gammaproteobacteria,1XJ0T@135619|Oceanospirillales 135619|Oceanospirillales U Belongs to the peptidase S26 family lepB - 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24,Peptidase_S26 k141_16139_1 1523503.JPMY01000013_gene3561 1.18e-38 139.0 COG2084@1|root,COG2084@2|Bacteria,1RA7F@1224|Proteobacteria,1RMMY@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Belongs to the 3-hydroxyisobutyrate dehydrogenase family mmsB - 1.1.1.31,1.1.1.387 ko:K00020,ko:K19711 ko00280,ko01100,map00280,map01100 - R05066 RC00099 ko00000,ko00001,ko01000 - - - NAD_binding_11,NAD_binding_2 k141_16139_2 1279017.AQYJ01000028_gene2376 1.46e-157 452.0 COG1024@1|root,COG1024@2|Bacteria,1MU0B@1224|Proteobacteria,1RN07@1236|Gammaproteobacteria,464P0@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1024 Enoyl-CoA hydratase carnithine racemase - - - - - - - - - - - - ECH_2 k141_27881_1 1121121.KB894304_gene3305 2.47e-48 168.0 COG0358@1|root,COG0358@2|Bacteria,1V5M7@1239|Firmicutes,4HHFB@91061|Bacilli,26WTR@186822|Paenibacillaceae 91061|Bacilli L Toprim-like - - - - - - - - - - - - Toprim_2 k141_14865_1 218284.CCDN010000001_gene1328 2.17e-92 285.0 COG5002@1|root,COG5002@2|Bacteria,1TPSK@1239|Firmicutes,4HAH5@91061|Bacilli,1ZB8J@1386|Bacillus 91061|Bacilli T Histidine kinase arlS GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 2.7.13.3 ko:K18940 ko02020,map02020 M00716,M00717 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA k141_18684_1 218284.CCDN010000001_gene1244 4.17e-159 458.0 COG0534@1|root,COG0534@2|Bacteria,1TP5U@1239|Firmicutes,4HA4W@91061|Bacilli,1ZAX6@1386|Bacillus 91061|Bacilli V Multidrug efflux pump norM GO:0003674,GO:0005215,GO:0006810,GO:0006855,GO:0008150,GO:0015238,GO:0015893,GO:0022857,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0046677,GO:0050896,GO:0051179,GO:0051234,GO:0055085 - ko:K03327 - - - - ko00000,ko02000 2.A.66.1 - - MatE k141_22067_1 1279017.AQYJ01000025_gene529 0.0 1644.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,46425@72275|Alteromonadaceae 1236|Gammaproteobacteria V Efflux pump acrB - - ko:K18138 ko01501,ko01503,map01501,map01503 M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2 - - ACR_tran k141_22067_2 983917.RGE_16450 2.59e-75 242.0 COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,2VINC@28216|Betaproteobacteria,1KJFG@119065|unclassified Burkholderiales 28216|Betaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family acrA - - ko:K03585 ko01501,ko01503,map01501,map01503 M00646,M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,8.A.1.6 - - Biotin_lipoyl_2,HlyD_D23 k141_11537_2 1294265.JCM21738_3819 6.58e-62 191.0 2BBAB@1|root,324T2@2|Bacteria,1UAI4@1239|Firmicutes,4IKWM@91061|Bacilli,1ZI3C@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_11537_3 1294265.JCM21738_3820 1.68e-83 247.0 COG3629@1|root,COG3629@2|Bacteria,1UWHI@1239|Firmicutes,4HADH@91061|Bacilli,1ZE89@1386|Bacillus 91061|Bacilli KT COG2909 ATP-dependent transcriptional regulator - - - ko:K03556 - - - - ko00000,ko03000 - - - AAA_16,BTAD,TPR_12,TPR_8 k141_9100_1 218284.CCDN010000010_gene4387 2.35e-135 387.0 COG1045@1|root,COG1045@2|Bacteria,1TR42@1239|Firmicutes,4HAKS@91061|Bacilli,1ZCNM@1386|Bacillus 91061|Bacilli E Serine acetyltransferase cysE GO:0000096,GO:0000097,GO:0000098,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009001,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009070,GO:0009087,GO:0009987,GO:0016053,GO:0016054,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.3.1.30 ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 M00021 R00586 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS02865,iYO844.BSU00930 Hexapep,SATase_N k141_7741_1 218284.CCDN010000001_gene1061 6.44e-108 327.0 COG1333@1|root,COG1333@2|Bacteria,1TQ6C@1239|Firmicutes,4HAFD@91061|Bacilli,1ZBB3@1386|Bacillus 91061|Bacilli O COG1333 ResB protein required for cytochrome c biosynthesis resB - - ko:K07399 - - - - ko00000 - - - ResB k141_7741_2 218284.CCDN010000001_gene1060 4.32e-93 275.0 COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,4HIQ3@91061|Bacilli,1ZCW1@1386|Bacillus 91061|Bacilli CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c resA GO:0008150,GO:0009987,GO:0016043,GO:0017004,GO:0022607,GO:0034622,GO:0043933,GO:0044085,GO:0065003,GO:0071840 - - - - - - - - - - AhpC-TSA k141_6702_1 1453501.JELR01000001_gene2283 8.45e-108 311.0 COG1376@1|root,COG1376@2|Bacteria,1Q823@1224|Proteobacteria 1224|Proteobacteria M ErfK ybiS ycfS ynhG family protein - - - - - - - - - - - - YkuD k141_6702_2 1453501.JELR01000001_gene2284 1.14e-96 283.0 COG0684@1|root,COG0684@2|Bacteria,1RH18@1224|Proteobacteria,1RS9U@1236|Gammaproteobacteria,466UJ@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions rraA GO:0003674,GO:0004857,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008428,GO:0009892,GO:0009894,GO:0009895,GO:0010605,GO:0019219,GO:0019222,GO:0030234,GO:0031323,GO:0031324,GO:0031329,GO:0031330,GO:0032069,GO:0032074,GO:0043086,GO:0044092,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060699,GO:0060700,GO:0060701,GO:0060702,GO:0065007,GO:0065009,GO:0080090,GO:0098772,GO:1902369 - ko:K02553 - - - - ko00000,ko03019 - - iJR904.b3929 RraA-like k141_12787_1 1288826.MSNKSG1_13767 1e-33 128.0 COG2010@1|root,COG2010@2|Bacteria,1MV6D@1224|Proteobacteria,1RMYF@1236|Gammaproteobacteria,466XG@72275|Alteromonadaceae 1236|Gammaproteobacteria C Cytochrome C oxidase, cbb3-type, subunit III - - - - - - - - - - - - Cytochrom_C,Cytochrome_CBB3 k141_12787_2 87626.PTD2_04316 1.09e-47 170.0 COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,1RNA5@1236|Gammaproteobacteria,2Q0BR@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria P Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity katG GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.11.1.21 ko:K03782 ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110 - R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906 RC00034,RC00213,RC00767,RC02141 ko00000,ko00001,ko01000 - - - peroxidase k141_25805_1 1453501.JELR01000001_gene2401 4.43e-105 306.0 COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,1RQ1J@1236|Gammaproteobacteria,466D5@72275|Alteromonadaceae 1236|Gammaproteobacteria KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain gacA - - ko:K07689 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 M00475 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg k141_27882_2 1540221.JQNI01000002_gene1007 6.48e-24 103.0 COG1253@1|root,COG1253@2|Bacteria,1WI7Q@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S COGs COG1253 Hemolysins and related protein containing CBS domains - - - - - - - - - - - - CBS,CorC_HlyC,DUF21 k141_9101_1 86416.Clopa_2105 3.23e-55 175.0 COG5646@1|root,COG5646@2|Bacteria,1V6QB@1239|Firmicutes,24K4J@186801|Clostridia,36JND@31979|Clostridiaceae 186801|Clostridia S Domain of unknown function (DU1801) - - - - - - - - - - - - DUF1801,OmdA k141_35270_1 218284.CCDN010000001_gene290 1.24e-97 286.0 COG1285@1|root,COG1285@2|Bacteria,1V409@1239|Firmicutes,4HGHY@91061|Bacilli,1ZBY0@1386|Bacillus 91061|Bacilli S MgtC SapB transporter - - - - - - - - - - - - MgtC k141_23433_1 498211.CJA_3211 1.31e-151 474.0 COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,1RPV3@1236|Gammaproteobacteria,1FGTE@10|Cellvibrio 1236|Gammaproteobacteria NU Neisseria PilC beta-propeller domain - - - ko:K02674 - - - - ko00000,ko02035,ko02044 - - - Neisseria_PilC,PA14 k141_7742_1 1123373.ATXI01000006_gene210 3.99e-32 128.0 COG0744@1|root,COG0744@2|Bacteria,2GHEW@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria M Transglycosylase - - 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase k141_14866_1 1382305.AZUC01000014_gene2314 6.04e-28 106.0 COG0127@1|root,COG0127@2|Bacteria,1V6RN@1239|Firmicutes,4HCP6@91061|Bacilli,26DZR@186818|Planococcaceae 91061|Bacilli F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions rdgB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 ko:K02428 ko00230,map00230 - R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000 - - - Ham1p_like k141_14866_2 218284.CCDN010000001_gene588 5.39e-83 249.0 COG0622@1|root,COG0622@2|Bacteria,1VA0U@1239|Firmicutes,4HM24@91061|Bacilli,1ZH0K@1386|Bacillus 91061|Bacilli S Phosphoesterase ysnB GO:0003674,GO:0005488,GO:0008270,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - ko:K07095 - - - - ko00000 - - - Metallophos_2 k141_17296_1 935836.JAEL01000006_gene2846 1.96e-39 140.0 COG0500@1|root,COG2226@2|Bacteria,1U9IT@1239|Firmicutes,4HDV5@91061|Bacilli,1ZC30@1386|Bacillus 91061|Bacilli Q Methionine biosynthesis protein MetW rebM - - - - - - - - - - - Methyltransf_11 k141_22069_1 218284.CCDN010000005_gene3485 4.05e-47 162.0 COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TPJ8@1239|Firmicutes,4HA8X@91061|Bacilli,1ZAZ3@1386|Bacillus 91061|Bacilli G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific nagE - 2.7.1.193,2.7.1.199 ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 M00267,M00809 R02738,R05199 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.13,4.A.1.1.14,4.A.1.1.15,4.A.1.1.2,4.A.1.1.5,4.A.1.1.7,4.A.1.1.9 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC k141_14001_2 218284.CCDN010000001_gene608 4.5e-35 119.0 2ESUV@1|root,33KD9@2|Bacteria,1VP5F@1239|Firmicutes,4HSYB@91061|Bacilli,1ZIWU@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_20822_2 1279017.AQYJ01000028_gene2103 1.43e-189 533.0 COG0126@1|root,COG0126@2|Bacteria,1MUNU@1224|Proteobacteria,1RMUQ@1236|Gammaproteobacteria,464NK@72275|Alteromonadaceae 1236|Gammaproteobacteria G Belongs to the phosphoglycerate kinase family pgk GO:0003674,GO:0003824,GO:0004618,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.2.3 ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01512 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000,ko04147 - - iSbBS512_1146.SbBS512_E3351 PGK k141_29178_1 1453501.JELR01000005_gene1569 1.2e-102 332.0 COG1361@1|root,COG3210@1|root,COG1361@2|Bacteria,COG3210@2|Bacteria,1QUXB@1224|Proteobacteria,1T5IP@1236|Gammaproteobacteria 1236|Gammaproteobacteria MU Domain of unknown function (DUF4347) - - - - - - - - - - - - DUF11,DUF4347 k141_11539_1 1234664.AMRO01000079_gene544 2.76e-76 234.0 COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4I3JR@91061|Bacilli,1WH63@129337|Geobacillus 91061|Bacilli P Binding-protein-dependent transport system inner membrane component - - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 k141_18686_1 1294265.JCM21738_1314 1.45e-75 226.0 COG1098@1|root,COG1098@2|Bacteria,1VASQ@1239|Firmicutes,4HKSW@91061|Bacilli,1ZHK5@1386|Bacillus 91061|Bacilli J RNA binding protein (contains ribosomal protein S1 domain) yugI - - ko:K07570,ko:K07571 - - - - ko00000 - - - S1 k141_2988_1 1187848.AJYQ01000004_gene200 1.4e-288 794.0 COG2895@1|root,COG2895@2|Bacteria,1MUD9@1224|Proteobacteria,1RME4@1236|Gammaproteobacteria,1XSCY@135623|Vibrionales 135623|Vibrionales H Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily cysN - 2.7.7.4 ko:K00956 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176,M00596 R00529,R04929 RC02809,RC02889 ko00000,ko00001,ko00002,ko01000 - - - GTP_EFTU,GTP_EFTU_D3 k141_2988_2 1116375.VEJY3_10295 1.31e-273 752.0 COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,1RMEN@1236|Gammaproteobacteria,1XTN6@135623|Vibrionales 135623|Vibrionales U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family gltP - - - - - - - - - - - SDF k141_2988_3 1116375.VEJY3_10290 4.66e-128 377.0 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1RMQ4@1236|Gammaproteobacteria,1XV4V@135623|Vibrionales 135623|Vibrionales IQ AMP-binding enzyme C-terminal domain - - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding,AMP-binding_C k141_10365_1 926550.CLDAP_00280 3.96e-87 272.0 COG1257@1|root,COG1257@2|Bacteria 2|Bacteria I hydroxymethylglutaryl-CoA reductase (NADPH) activity hmgA - 1.1.1.34 ko:K00021 ko00900,ko01100,ko01110,ko01130,ko04152,ko04976,map00900,map01100,map01110,map01130,map04152,map04976 M00095 R02082 RC00004,RC00644 ko00000,ko00001,ko00002,ko01000 - - - HMG-CoA_red k141_4252_1 1279017.AQYJ01000026_gene28 1.17e-87 259.0 COG1956@1|root,COG1956@2|Bacteria,1RDBM@1224|Proteobacteria,1S6QU@1236|Gammaproteobacteria,4670T@72275|Alteromonadaceae 1236|Gammaproteobacteria T GAF domain-containing protein yebR GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0016491,GO:0016667,GO:0016671,GO:0033745,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.8.4.14 ko:K08968 ko00270,map00270 - R02025 RC00639 ko00000,ko00001,ko01000 - - - GAF_2 k141_4252_2 1042377.AFPJ01000016_gene152 4.63e-97 291.0 COG0421@1|root,COG0421@2|Bacteria,1QWZZ@1224|Proteobacteria,1T31M@1236|Gammaproteobacteria,467WD@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - - - - - - - - - - Methyltransf_25 k141_4252_3 1279017.AQYJ01000026_gene26 1.2e-73 224.0 2EKB9@1|root,33E1N@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k141_1774_1 218284.CCDN010000001_gene779 8.47e-206 573.0 COG0821@1|root,COG0821@2|Bacteria,1TPFR@1239|Firmicutes,4H9S1@91061|Bacilli,1ZCV1@1386|Bacillus 91061|Bacilli I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate ispG GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R08689,R10859 RC01486 ko00000,ko00001,ko00002,ko01000 - - - GcpE k141_35271_1 96561.Dole_2895 7.3e-48 174.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJVV@28221|Deltaproteobacteria,2MI7E@213118|Desulfobacterales 28221|Deltaproteobacteria V Hydrophobe Amphiphile Efflux-1 (HAE1) Family acrB - - ko:K03296,ko:K18138 ko01501,ko01503,map01501,map01503 M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2 - - ACR_tran k141_16140_1 317025.Tcr_1066 4.67e-90 280.0 COG0531@1|root,COG0531@2|Bacteria,1QXK2@1224|Proteobacteria,1S18B@1236|Gammaproteobacteria 1236|Gammaproteobacteria E amino acid - - - ko:K07076 - - - - ko00000 - - - AA_permease_2 k141_7743_1 1158601.I585_01172 2.98e-19 82.0 2EC8I@1|root,33670@2|Bacteria,1VENI@1239|Firmicutes,4HR98@91061|Bacilli,4B4AS@81852|Enterococcaceae 91061|Bacilli - - - - - - - - - - - - - - - k141_20823_1 1294265.JCM21738_2916 5.67e-113 332.0 COG0189@1|root,COG0189@2|Bacteria,1V1EV@1239|Firmicutes,4HFNI@91061|Bacilli,1ZBM5@1386|Bacillus 91061|Bacilli HJ YheC/D like ATP-grasp - - - - - - - - - - - - ATPgrasp_YheCD k141_6703_1 345219.Bcoa_1313 1.07e-09 61.6 COG4863@1|root,COG4863@2|Bacteria,1UV48@1239|Firmicutes,4HF30@91061|Bacilli,1ZD30@1386|Bacillus 91061|Bacilli S protein conserved in bacteria yycH - - - - - - - - - - - YycH k141_6703_2 218284.CCDN010000007_gene3828 4.34e-97 292.0 COG4853@1|root,COG4853@2|Bacteria,1V1FW@1239|Firmicutes,4HFWZ@91061|Bacilli,1ZDGV@1386|Bacillus 91061|Bacilli S protein conserved in bacteria yycI - - - - - - - - - - - YycI k141_34022_1 1116375.VEJY3_01420 1.75e-135 386.0 COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,1RPMP@1236|Gammaproteobacteria,1XTFI@135623|Vibrionales 135623|Vibrionales O COG0545 FKBP-type peptidyl-prolyl cis-trans isomerases 1 fklB - 5.2.1.8 ko:K03773 - - - - ko00000,ko01000,ko03110 - - - FKBP_C,FKBP_N k141_37448_13 1116375.VEJY3_05685 5.02e-94 273.0 2B2JB@1|root,31V4J@2|Bacteria,1N4EU@1224|Proteobacteria,1S6JW@1236|Gammaproteobacteria,1XXC5@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF2750) VV1382 - - - - - - - - - - - DUF2750 k141_37448_14 223926.28806155 2.99e-92 275.0 COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,1RMEI@1236|Gammaproteobacteria,1XTTI@135623|Vibrionales 135623|Vibrionales P ABC-type antimicrobial peptide transport system, ATPase component sapF - - ko:K19230 ko01503,ko02010,map01503,map02010 M00739 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.5 - - ABC_tran k141_32689_1 1294265.JCM21738_146 7.06e-32 117.0 COG0413@1|root,COG0413@2|Bacteria,1TPZA@1239|Firmicutes,4H9S8@91061|Bacilli,1ZAWV@1386|Bacillus 91061|Bacilli H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate panB - 2.1.2.11 ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R01226 RC00022,RC00200 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU22430 Pantoate_transf k141_24747_3 634176.NT05HA_0334 2.95e-64 206.0 2ARW5@1|root,31H7Z@2|Bacteria,1QI92@1224|Proteobacteria,1TG37@1236|Gammaproteobacteria,1YAPE@135625|Pasteurellales 135625|Pasteurellales - - - - - - - - - - - - - - - k141_24747_4 189426.PODO_29785 6.17e-61 192.0 COG0251@1|root,COG0251@2|Bacteria,1V4N4@1239|Firmicutes,4HH19@91061|Bacilli,275TF@186822|Paenibacillaceae 91061|Bacilli J Endoribonuclease L-PSP - - - - - - - - - - - - YjgF_endoribonc k141_34236_1 218284.CCDN010000001_gene1678 2.23e-81 245.0 COG1309@1|root,COG1309@2|Bacteria,1V6CF@1239|Firmicutes,4HJIC@91061|Bacilli,1ZFKI@1386|Bacillus 91061|Bacilli K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N k141_34236_2 218284.CCDN010000001_gene1677 2.22e-27 109.0 COG0477@1|root,COG2814@2|Bacteria,1TPRN@1239|Firmicutes,4H9VV@91061|Bacilli,1ZAXQ@1386|Bacillus 91061|Bacilli EGP the major facilitator superfamily emrB_2 - - - - - - - - - - - MFS_1 k141_10484_1 1279017.AQYJ01000027_gene1719 1.49e-105 328.0 COG0803@1|root,COG0803@2|Bacteria,1MY4H@1224|Proteobacteria,1S26I@1236|Gammaproteobacteria,46AMU@72275|Alteromonadaceae 1236|Gammaproteobacteria P Belongs to the bacterial solute-binding protein 9 family - - - - - - - - - - - - DUF4175 k141_29423_1 42565.FP66_01920 9.19e-116 335.0 COG4106@1|root,COG4106@2|Bacteria,1QTS9@1224|Proteobacteria,1T1FG@1236|Gammaproteobacteria,1XJEA@135619|Oceanospirillales 135619|Oceanospirillales S Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM) cmoA - - ko:K15256 - - - - ko00000,ko01000,ko03016 - - - Methyltransf_25 k141_29423_2 42565.FP66_01915 3.28e-28 108.0 COG2227@1|root,COG2227@2|Bacteria,1NN3B@1224|Proteobacteria,1T1TQ@1236|Gammaproteobacteria,1XHUZ@135619|Oceanospirillales 135619|Oceanospirillales J Catalyzes carboxymethyl transfer from carboxy-S- adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs cmoB - - ko:K15257 - - - - ko00000,ko01000,ko03016 - - - Methyltransf_9 k141_22442_1 218284.CCDN010000001_gene562 4.35e-166 466.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,4H9QY@91061|Bacilli,1ZBTA@1386|Bacillus 91061|Bacilli C Electron transfer flavoprotein etfB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114 - ko:K03521 - - - - ko00000 - - - ETF k141_7052_2 1116375.VEJY3_13225 5.54e-87 261.0 COG1694@1|root,COG3956@2|Bacteria,1MVKM@1224|Proteobacteria,1RNVU@1236|Gammaproteobacteria,1XVCP@135623|Vibrionales 135623|Vibrionales S Nucleoside triphosphate mazG - 3.6.1.9 ko:K04765 ko00230,ko00240,ko00760,ko00770,ko01100,map00230,map00240,map00760,map00770,map01100 - R00086,R00087,R00103,R00287,R00426,R00515,R00662,R00720,R03004,R03036,R11323 RC00002 ko00000,ko00001,ko01000 - - - MazG k141_5783_1 218284.CCDN010000003_gene3016 3.23e-142 413.0 COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,4H9X4@91061|Bacilli,1ZAVI@1386|Bacillus 91061|Bacilli J Belongs to the class-II aminoacyl-tRNA synthetase family lysS - 6.1.1.6 ko:K04567 ko00970,map00970 M00359,M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2,tRNA_anti-codon k141_1969_1 485913.Krac_2435 4.85e-48 165.0 COG1319@1|root,COG1319@2|Bacteria 2|Bacteria C xanthine dehydrogenase activity hcrB - 1.3.7.9 ko:K04109 ko00362,ko00627,ko01100,ko01120,ko01220,map00362,map00627,map01100,map01120,map01220 - R05316 RC00490 ko00000,ko00001,ko01000 - - - CO_deh_flav_C,FAD_binding_5 k141_17427_1 1218173.BALCAV_0214635 1.48e-62 202.0 COG1879@1|root,COG1879@2|Bacteria,1TQZS@1239|Firmicutes,4HCUS@91061|Bacilli,1ZB0G@1386|Bacillus 91061|Bacilli G Periplasmic binding protein LacI transcriptional regulator - - - ko:K10439 ko02010,ko02030,map02010,map02030 M00212 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - Peripla_BP_4 k141_17427_2 1408303.JNJJ01000010_gene2369 1.25e-20 91.3 COG2972@1|root,COG2972@2|Bacteria,1TSF9@1239|Firmicutes,4HAIW@91061|Bacilli,1ZC6Y@1386|Bacillus 91061|Bacilli T Histidine kinase - - - - - - - - - - - - HAMP,HATPase_c,His_kinase k141_37633_2 218284.CCDN010000001_gene1137 7.2e-65 207.0 COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1TQCU@1239|Firmicutes,4HB60@91061|Bacilli,1ZBI9@1386|Bacillus 91061|Bacilli K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor birA - 6.3.4.15 ko:K03524 ko00780,ko01100,map00780,map01100 - R01074,R05145 RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko01000,ko03000 - - - BPL_C,BPL_LplA_LipB,HTH_11 k141_5784_1 218284.CCDN010000005_gene3252 4.77e-152 433.0 COG1609@1|root,COG1609@2|Bacteria,1TPZM@1239|Firmicutes,4H9ZT@91061|Bacilli,1ZB2U@1386|Bacillus 91061|Bacilli K Transcriptional regulator malR - - - - - - - - - - - LacI,Peripla_BP_3 k141_32944_1 218284.CCDN010000001_gene1896 2.33e-152 436.0 COG0743@1|root,COG0743@2|Bacteria,1TP1C@1239|Firmicutes,4HBAV@91061|Bacilli,1ZC3I@1386|Bacillus 91061|Bacilli I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) dxr GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05688 RC01452 ko00000,ko00001,ko00002,ko01000 - - - DXPR_C,DXP_redisom_C,DXP_reductoisom k141_16356_1 1423321.AS29_15385 3.08e-185 530.0 COG1409@1|root,COG1409@2|Bacteria 2|Bacteria S acid phosphatase activity - - - - - - - - - - - - CHAT,HEAT_2,HEAT_PBS,Metallophos,NACHT k141_11820_1 1294265.JCM21738_4720 7.94e-157 457.0 COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HA0V@91061|Bacilli,1ZBTK@1386|Bacillus 91061|Bacilli O Belongs to the ClpA ClpB family clpE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03697,ko:K04086 - - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,UVR k141_24748_1 1265313.HRUBRA_02811 0.000723 44.7 COG1629@1|root,COG4771@2|Bacteria,1QYDM@1224|Proteobacteria,1RYCH@1236|Gammaproteobacteria,1J53M@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_24748_2 1125863.JAFN01000001_gene1171 0.000193 49.7 COG2267@1|root,COG2267@2|Bacteria,1MX0N@1224|Proteobacteria,42UNC@68525|delta/epsilon subdivisions 1224|Proteobacteria I TAP-like protein - - 3.1.1.24 ko:K01055 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00568 R02991 RC00825 ko00000,ko00001,ko00002,ko01000 - - - Abhydrolase_1,Abhydrolase_4,Abhydrolase_6 k141_36417_2 1185876.BN8_04657 2.35e-37 133.0 COG2329@1|root,COG2329@2|Bacteria,4NQGS@976|Bacteroidetes,47QSH@768503|Cytophagia 976|Bacteroidetes S Domain of unknown function (DUF3291) - - - - - - - - - - - - DUF3291 k141_31560_1 881621.LIV_1270 1.33e-06 49.7 COG0442@1|root,COG0442@2|Bacteria,1TRBV@1239|Firmicutes,4H9NN@91061|Bacilli,26JBS@186820|Listeriaceae 91061|Bacilli J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS proS - 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_2b,tRNA_edit k141_28050_1 1279017.AQYJ01000024_gene1022 4.84e-49 174.0 COG1835@1|root,COG1835@2|Bacteria,1MV2W@1224|Proteobacteria,1RQS2@1236|Gammaproteobacteria,465QX@72275|Alteromonadaceae 1236|Gammaproteobacteria I Acyltransferase - - - - - - - - - - - - Acyl_transf_3 k141_15120_1 1116375.VEJY3_24356 2.57e-165 475.0 COG4166@1|root,COG4166@2|Bacteria,1P91R@1224|Proteobacteria,1RN57@1236|Gammaproteobacteria,1XVN1@135623|Vibrionales 135623|Vibrionales E Bacterial extracellular solute-binding proteins, family 5 Middle - - - ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 k141_20989_1 312309.VF_A0351 1.81e-131 388.0 COG4146@1|root,COG4146@2|Bacteria,1MXWV@1224|Proteobacteria,1RR4S@1236|Gammaproteobacteria,1XW1R@135623|Vibrionales 135623|Vibrionales S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family yidK - - ko:K03307 - - - - ko00000 2.A.21 - - SSF k141_20989_2 223926.28808756 1.73e-224 624.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1XTGW@135623|Vibrionales 135623|Vibrionales JKL Belongs to the DEAD box helicase family - - - - - - - - - - - - DEAD,Helicase_C k141_16357_1 861299.J421_2159 2.67e-74 226.0 COG2080@1|root,COG2080@2|Bacteria 2|Bacteria C 2 iron, 2 sulfur cluster binding coxS - 1.2.5.3,1.3.99.16 ko:K03518,ko:K07302,ko:K13483 ko00230,ko01100,ko01120,map00230,map01100,map01120 M00546 R01768,R02103,R11168 RC00143,RC02800 ko00000,ko00001,ko00002,ko01000 - - - Fer2,Fer2_2 k141_35519_1 1453501.JELR01000002_gene964 4.08e-109 326.0 COG3071@1|root,COG3071@2|Bacteria,1MU7A@1224|Proteobacteria,1RMRG@1236|Gammaproteobacteria,46647@72275|Alteromonadaceae 1236|Gammaproteobacteria H enzyme of heme biosynthesis hemY GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02498 - - - - ko00000 - - - HemY_N,TPR_2 k141_7055_1 226185.EF_1305 2.74e-27 108.0 COG0635@1|root,COG0635@2|Bacteria,1TPES@1239|Firmicutes,4HA60@91061|Bacilli,4AZGX@81852|Enterococcaceae 91061|Bacilli H Involved in the biosynthesis of porphyrin-containing compound hemN GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - - - - - - - - - - HemN_C,Radical_SAM k141_34237_1 945550.VISI1226_13673 2.12e-35 137.0 2AX11@1|root,31NZ2@2|Bacteria,1QKNB@1224|Proteobacteria,1TIST@1236|Gammaproteobacteria,1XZKD@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_28051_1 218284.CCDN010000002_gene2662 2.07e-111 330.0 COG1055@1|root,COG1055@2|Bacteria,1TPNN@1239|Firmicutes,4H9WV@91061|Bacilli,1ZBHC@1386|Bacillus 91061|Bacilli P Involved in arsenical resistance. Thought to form the channel of an arsenite pump ydfA - - ko:K03893 - - - - ko00000,ko02000 2.A.45.1,3.A.4.1 - - ArsB k141_36425_1 42565.FP66_09425 2.06e-154 451.0 COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,1RNPT@1236|Gammaproteobacteria,1XI9U@135619|Oceanospirillales 135619|Oceanospirillales C The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) aceF - 2.3.1.12 ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding k141_9437_1 1294265.JCM21738_3286 2.22e-110 325.0 COG1420@1|root,COG1420@2|Bacteria,1TQP7@1239|Firmicutes,4HAX5@91061|Bacilli,1ZBQV@1386|Bacillus 91061|Bacilli K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons hrcA GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K03705 - - - - ko00000,ko03000 - - - HrcA,HrcA_DNA-bdg k141_32971_1 1238186.AOCN01000012_gene1308 6.69e-44 157.0 COG0438@1|root,COG0438@2|Bacteria,2IBM0@201174|Actinobacteria,4FMSS@85023|Microbacteriaceae 201174|Actinobacteria M Domain of unknown function (DUF1972) - - - ko:K12996 - - - - ko00000,ko01000,ko01003,ko01005 - GT4 - DUF1972,Glyco_trans_1_2,Glyco_trans_1_4,Glyco_trans_4_4,Glycos_transf_1 k141_15127_1 406124.ACPC01000012_gene1064 2.93e-108 337.0 COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,4HAWB@91061|Bacilli,1ZAQK@1386|Bacillus 91061|Bacilli J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS - 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1,zf-FPG_IleRS k141_20039_1 1121937.AUHJ01000028_gene930 1.47e-123 433.0 COG1372@1|root,COG1520@1|root,COG3209@1|root,COG1372@2|Bacteria,COG1520@2|Bacteria,COG3209@2|Bacteria,1QW4H@1224|Proteobacteria,1T42N@1236|Gammaproteobacteria,46DDZ@72275|Alteromonadaceae 1236|Gammaproteobacteria LM Rhs Family - - - - - - - - - - - - Cadherin,DUF5122,He_PIG,PT-HINT,RHS_repeat k141_21002_1 1294265.JCM21738_2004 4.98e-06 47.4 COG0628@1|root,COG0628@2|Bacteria,1TSI9@1239|Firmicutes,4HB3Q@91061|Bacilli,1ZD70@1386|Bacillus 91061|Bacilli S AI-2E family transporter - - - - - - - - - - - - AI-2E_transport k141_21002_2 1294265.JCM21738_2005 8.92e-57 181.0 COG2094@1|root,COG2094@2|Bacteria,1V1E6@1239|Firmicutes,4HG5E@91061|Bacilli,1ZFWT@1386|Bacillus 91061|Bacilli L Belongs to the DNA glycosylase MPG family yxlJ GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.2.2.21 ko:K03652 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Pur_DNA_glyco k141_22459_1 1267533.KB906740_gene380 5.39e-50 177.0 COG0577@1|root,COG0577@2|Bacteria,3Y2MV@57723|Acidobacteria,2JI8C@204432|Acidobacteriia 204432|Acidobacteriia V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD k141_30417_1 406124.ACPC01000018_gene2616 1.25e-68 223.0 28KI6@1|root,2ZA3G@2|Bacteria,1UYE9@1239|Firmicutes,4HB9Y@91061|Bacilli,1ZF3A@1386|Bacillus 91061|Bacilli S Spore germination B3/ GerAC like, C-terminal - - - - - - - - - - - - Spore_GerAC k141_1989_1 670292.JH26_00425 2.09e-104 309.0 COG2801@1|root,COG2801@2|Bacteria,1MVN5@1224|Proteobacteria,2TQK0@28211|Alphaproteobacteria,1JTSW@119045|Methylobacteriaceae 28211|Alphaproteobacteria L PFAM Integrase catalytic region - - - - - - - - - - - - HTH_21,rve,rve_3 k141_36426_1 218284.CCDN010000001_gene41 6.39e-55 191.0 COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,4H9KD@91061|Bacilli,1ZBBU@1386|Bacillus 91061|Bacilli KLT serine threonine protein kinase prkC GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 ko:K08884,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PASTA,Pkinase k141_3253_1 1116375.VEJY3_04295 1.93e-189 531.0 COG2855@1|root,COG2855@2|Bacteria,1MVIP@1224|Proteobacteria,1RPSG@1236|Gammaproteobacteria,1XTQB@135623|Vibrionales 135623|Vibrionales S membrane - - - - - - - - - - - - Cons_hypoth698 k141_29451_2 218284.CCDN010000001_gene33 1.17e-64 201.0 COG1760@1|root,COG1760@2|Bacteria,1U8TZ@1239|Firmicutes,4HBD6@91061|Bacilli,1ZCRK@1386|Bacillus 91061|Bacilli E L-serine dehydratase sdaAB GO:0003674,GO:0003824,GO:0003941,GO:0016829,GO:0016840,GO:0016841 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 - R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 - - - ACT,SDH_beta k141_7079_1 1196324.A374_08714 8.55e-28 119.0 COG0739@1|root,COG5280@1|root,COG5412@1|root,COG0739@2|Bacteria,COG5280@2|Bacteria,COG5412@2|Bacteria,1TQ28@1239|Firmicutes,4IUGP@91061|Bacilli 91061|Bacilli M Phage tail tape measure protein, TP901 family - - - - - - - - - - - - - k141_16374_1 42565.FP66_08075 4.86e-152 444.0 COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,1RN4X@1236|Gammaproteobacteria,1XH36@135619|Oceanospirillales 135619|Oceanospirillales L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topB - 5.99.1.2 ko:K03169 - - - - ko00000,ko01000,ko03032 - - - Topoisom_bac,Toprim k141_1990_1 1227360.C176_06932 1.13e-14 69.7 COG0454@1|root,COG0456@2|Bacteria,1VAU8@1239|Firmicutes,4IQ7V@91061|Bacilli,26G96@186818|Planococcaceae 91061|Bacilli K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - - - - - - - - - - Acetyltransf_1 k141_1990_2 1395513.P343_00230 2.13e-63 203.0 COG0500@1|root,COG2226@2|Bacteria,1VIXJ@1239|Firmicutes,4HGT9@91061|Bacilli 91061|Bacilli Q ubiE/COQ5 methyltransferase family - - - - - - - - - - - - Methyltransf_11,Methyltransf_25 k141_9440_2 1279017.AQYJ01000020_gene1330 9.68e-12 64.7 COG2269@1|root,COG2269@2|Bacteria,1MU97@1224|Proteobacteria,1RMR9@1236|Gammaproteobacteria,4645R@72275|Alteromonadaceae 1236|Gammaproteobacteria J COG2269 Truncated, possibly inactive, lysyl-tRNA synthetase (class II) epmA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006430,GO:0006464,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016746,GO:0016755,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052868,GO:0071704,GO:0071915,GO:0072580,GO:0072581,GO:0090304,GO:0140096,GO:1901360,GO:1901564,GO:1901566,GO:1901576 - ko:K04568 - - - - ko00000,ko01000,ko03012 - - - tRNA-synt_2 k141_12980_1 1042377.AFPJ01000031_gene573 2.16e-66 217.0 COG2198@1|root,COG2198@2|Bacteria,1QY43@1224|Proteobacteria,1S0ZB@1236|Gammaproteobacteria,4641V@72275|Alteromonadaceae 1236|Gammaproteobacteria T Histidine kinase fimL - - - - - - - - - - - Hpt k141_9441_1 42565.FP66_02960 7.58e-78 239.0 COG2334@1|root,COG2334@2|Bacteria,1MUKJ@1224|Proteobacteria,1RPR6@1236|Gammaproteobacteria,1XIP1@135619|Oceanospirillales 135619|Oceanospirillales F Belongs to the pseudomonas-type ThrB family thrB - 2.7.1.39 ko:K02204 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 M00018 R01771 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - APH k141_21003_1 218284.CCDN010000001_gene1935 2.24e-72 219.0 COG1815@1|root,COG1815@2|Bacteria,1VEUZ@1239|Firmicutes,4HIKW@91061|Bacilli,1ZHSN@1386|Bacillus 91061|Bacilli N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body flgB - - ko:K02387 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod k141_21003_2 218284.CCDN010000001_gene1934 5.04e-96 280.0 COG1558@1|root,COG1558@2|Bacteria,1V6NB@1239|Firmicutes,4HH4W@91061|Bacilli,1ZGA0@1386|Bacillus 91061|Bacilli N Belongs to the flagella basal body rod proteins family flgC GO:0001539,GO:0005575,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009424,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588 - ko:K02388 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C k141_22462_1 323850.Shew_1876 6.9e-91 286.0 COG1082@1|root,COG1082@2|Bacteria,1NNTS@1224|Proteobacteria,1RP3I@1236|Gammaproteobacteria,2QAKD@267890|Shewanellaceae 1236|Gammaproteobacteria G Glycosyl-hydrolase 97 C-terminal, oligomerisation - - 3.2.1.20 ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00028,R00801,R00802,R06087,R06088 RC00028,RC00049,RC00077 ko00000,ko00001,ko01000 - GH31 - GH97_C,GH97_N,Glyco_hydro_97 k141_7081_1 218284.CCDN010000001_gene661 8.31e-111 340.0 COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,1TQVT@1239|Firmicutes,4HB6K@91061|Bacilli,1ZBS9@1386|Bacillus 91061|Bacilli U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secD GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD_SecF,Sec_GG k141_20040_1 1379698.RBG1_1C00001G1712 1.59e-61 203.0 COG0104@1|root,COG0104@2|Bacteria,2NNYU@2323|unclassified Bacteria 2|Bacteria F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP purA GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 - - - Adenylsucc_synt k141_15129_2 1042377.AFPJ01000007_gene1876 1.81e-09 57.8 COG1463@1|root,COG1463@2|Bacteria,1MU4B@1224|Proteobacteria,1S5E8@1236|Gammaproteobacteria,46BX6@72275|Alteromonadaceae 1236|Gammaproteobacteria Q MlaD protein - - - ko:K02067 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaD k141_1086_1 28229.ND2E_0933 9.93e-89 268.0 COG1011@1|root,COG1011@2|Bacteria,1MVWN@1224|Proteobacteria,1RR0H@1236|Gammaproteobacteria 1236|Gammaproteobacteria S haloacid dehalogenase - - 3.8.1.2 ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 - R05287 RC00697 ko00000,ko00001,ko01000 - - - HAD_2 k141_1086_2 1336233.JAEH01000038_gene4185 4.35e-98 291.0 COG2761@1|root,COG2761@2|Bacteria,1NXUB@1224|Proteobacteria,1S2Z2@1236|Gammaproteobacteria,2QDNS@267890|Shewanellaceae 1236|Gammaproteobacteria Q DSBA-like thioredoxin domain - - - - - - - - - - - - DSBA k141_1086_3 1116375.VEJY3_16946 1.17e-183 512.0 COG1806@1|root,COG1806@2|Bacteria,1MUHU@1224|Proteobacteria,1RPHX@1236|Gammaproteobacteria,1XT39@135623|Vibrionales 135623|Vibrionales F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation ydiA - 2.7.11.33,2.7.4.28 ko:K09773 - - - - ko00000,ko01000 - - - Kinase-PPPase k141_1086_4 1116375.VEJY3_16941 0.0 1533.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,1RP3T@1236|Gammaproteobacteria,1XSMW@135623|Vibrionales 135623|Vibrionales H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate ppsA - 2.7.9.2 ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 M00173,M00374 R00199 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - PEP-utilizers,PEP-utilizers_C,PPDK_N k141_4436_2 1279017.AQYJ01000027_gene1740 0.0 1494.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,465DD@72275|Alteromonadaceae 1236|Gammaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k141_4436_4 663610.JQKO01000003_gene1457 1.53e-37 139.0 COG2187@1|root,COG2187@2|Bacteria,1MU9M@1224|Proteobacteria,2TQJN@28211|Alphaproteobacteria,3NAZ0@45404|Beijerinckiaceae 28211|Alphaproteobacteria S Aminoglycoside phosphotransferase - - - - - - - - - - - - - k141_28066_1 318161.Sden_2427 4.29e-92 299.0 COG1629@1|root,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria,2Q8IQ@267890|Shewanellaceae 1236|Gammaproteobacteria P TonB-dependent receptor plug - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_36429_1 926550.CLDAP_37410 4.5e-13 69.7 COG1136@1|root,COG1136@2|Bacteria,2G8HT@200795|Chloroflexi 200795|Chloroflexi V PFAM ABC transporter related - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_36429_2 1121929.KB898682_gene2069 1.61e-07 53.1 COG3880@1|root,COG3880@2|Bacteria,1V6YM@1239|Firmicutes,4HH4R@91061|Bacilli,470NR@74385|Gracilibacillus 91061|Bacilli S UvrB/uvrC motif mcsA GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 - ko:K19411 - - - - ko00000 - - - UVR k141_22463_1 1453501.JELR01000002_gene351 9.48e-34 120.0 2B4XH@1|root,32REP@2|Bacteria,1RJ9F@1224|Proteobacteria,1T0SV@1236|Gammaproteobacteria,46BPI@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_37646_1 1340493.JNIF01000003_gene2966 2.3e-14 78.2 COG2227@1|root,COG2227@2|Bacteria 2|Bacteria H 3-demethylubiquinone-9 3-O-methyltransferase activity - - - - - - - - - - - - Glyco_trans_1_4,Glycos_transf_1,Glycos_transf_2,Methyltransf_11,Methyltransf_23,Methyltransf_25 k141_30419_1 218284.CCDN010000004_gene3078 1.46e-179 520.0 COG3973@1|root,COG3973@2|Bacteria,1TP39@1239|Firmicutes,4H9Y5@91061|Bacilli,1ZAWP@1386|Bacillus 91061|Bacilli L DNA helicase helD_2 - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_19,UvrD-helicase,UvrD_C,UvrD_C_2 k141_3255_1 218284.CCDN010000001_gene1345 5.06e-08 52.8 COG4915@1|root,COG4915@2|Bacteria,1V5B1@1239|Firmicutes,4HKAX@91061|Bacilli,1ZG4A@1386|Bacillus 91061|Bacilli S 5-bromo-4-chloroindolyl phosphate hydrolysis protein xpaC - - - - - - - - - - - Halogen_Hydrol k141_3255_2 218284.CCDN010000001_gene1344 9.65e-108 321.0 COG3853@1|root,COG3853@2|Bacteria,1TQVX@1239|Firmicutes,4H9Z6@91061|Bacilli,1ZATR@1386|Bacillus 91061|Bacilli P Belongs to the TelA family yaaN - - - - - - - - - - - TelA k141_1087_1 1385514.N782_02240 6.45e-34 119.0 COG0640@1|root,COG0640@2|Bacteria,1VEER@1239|Firmicutes,4HM9M@91061|Bacilli,2YAPA@289201|Pontibacillus 91061|Bacilli K ArsR family transcriptional regulator - - - ko:K03892,ko:K22043 - - - - ko00000,ko03000 - - - HTH_5 k141_1087_2 1246484.D479_00710 2.1e-69 222.0 COG1055@1|root,COG1055@2|Bacteria,1TPNN@1239|Firmicutes,4H9WV@91061|Bacilli,3NEDX@45667|Halobacillus 91061|Bacilli U Involved in arsenical resistance. Thought to form the channel of an arsenite pump arsB - - ko:K03893 - - - - ko00000,ko02000 2.A.45.1,3.A.4.1 - - ArsB k141_4437_1 1120972.AUMH01000010_gene276 1.77e-48 167.0 COG1562@1|root,COG1562@2|Bacteria 2|Bacteria I ergosterol biosynthetic process hpnC - 2.5.1.32,2.5.1.99,4.2.3.156 ko:K02291,ko:K21679 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 M00097 R02065,R04218,R07270,R10177 RC00362,RC01101,RC02869 ko00000,ko00001,ko00002,ko01000,ko01006 - - - SQS_PSY k141_3528_2 1279017.AQYJ01000024_gene862 3.47e-67 206.0 COG0858@1|root,COG0858@2|Bacteria,1MZPE@1224|Proteobacteria,1S9AF@1236|Gammaproteobacteria,46857@72275|Alteromonadaceae 1236|Gammaproteobacteria J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA rbfA GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030490,GO:0033554,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043021,GO:0043024,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - ko:K02834 - - - - ko00000,ko03009 - - - RBFA k141_2360_1 218284.CCDN010000001_gene1234 2.49e-108 319.0 COG0523@1|root,COG0523@2|Bacteria,1TPCG@1239|Firmicutes,4HFQ5@91061|Bacilli,1ZBXA@1386|Bacillus 91061|Bacilli S cobalamin synthesis protein P47K - - - - - - - - - - - - CobW_C,cobW k141_28392_1 218284.CCDN010000006_gene3613 3.65e-112 335.0 COG0696@1|root,COG0696@2|Bacteria,1TPM4@1239|Firmicutes,4HBTQ@91061|Bacilli,1ZAPE@1386|Bacillus 91061|Bacilli G Catalyzes the interconversion of 2-phosphoglycerate and gpmI GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030145,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0043937,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046537,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0050789,GO:0050793,GO:0051186,GO:0051188,GO:0055086,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.4.2.12 ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000 - - - Metalloenzyme,Phosphodiest,iPGM_N k141_21353_1 218284.CCDN010000001_gene741 3.84e-80 246.0 COG1283@1|root,COG1283@2|Bacteria,1TP4K@1239|Firmicutes,4HAZ0@91061|Bacilli,1ZBHZ@1386|Bacillus 91061|Bacilli P COG1283 Na phosphate symporter yqeW - - ko:K03324 - - - - ko00000,ko02000 2.A.58.2 - - Na_Pi_cotrans k141_33276_1 1116375.VEJY3_23456 4.19e-278 773.0 COG1505@1|root,COG1505@2|Bacteria,1NZ7N@1224|Proteobacteria,1T1KJ@1236|Gammaproteobacteria,1XVJ2@135623|Vibrionales 135623|Vibrionales E Prolyl endopeptidase - - 3.4.21.26 ko:K01322 ko04614,map04614 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S9,Peptidase_S9_N k141_21354_1 218284.CCDN010000002_gene2714 3.41e-42 151.0 COG1132@1|root,COG1132@2|Bacteria,1VS01@1239|Firmicutes,4HTGJ@91061|Bacilli,1ZEQ6@1386|Bacillus 91061|Bacilli V ABC transporter transmembrane region - - - - - - - - - - - - ABC_membrane,ABC_tran k141_21354_2 1501230.ET33_33455 2.43e-05 46.6 COG1309@1|root,COG1309@2|Bacteria,1V88I@1239|Firmicutes,4IPKN@91061|Bacilli,276D6@186822|Paenibacillaceae 91061|Bacilli K Transcriptional regulator C-terminal region - - - - - - - - - - - - TetR_C_8,TetR_N k141_15319_1 218284.CCDN010000001_gene1801 2.44e-94 282.0 COG0464@1|root,COG0464@2|Bacteria,1TPQZ@1239|Firmicutes,4HCQK@91061|Bacilli,1ZBII@1386|Bacillus 91061|Bacilli O stage V sporulation protein K spoVK - - ko:K06413 - - - - ko00000 - - - AAA k141_33277_1 218284.CCDN010000002_gene2121 1.41e-130 383.0 COG0119@1|root,COG0119@2|Bacteria,1TP4Y@1239|Firmicutes,4HA6E@91061|Bacilli,1ZC5T@1386|Bacillus 91061|Bacilli E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) leuA - 2.3.3.13 ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 M00432 R01213 RC00004,RC00470,RC02754 br01601,ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS10690,iYO844.BSU28280 HMGL-like,LeuA_dimer k141_33277_2 218284.CCDN010000002_gene2120 4.64e-10 58.9 COG0059@1|root,COG0059@2|Bacteria,1TPI7@1239|Firmicutes,4HADK@91061|Bacilli,1ZCH5@1386|Bacillus 91061|Bacilli EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate ilvC - 1.1.1.86 ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R03051,R04439,R04440,R05068,R05069,R05071 RC00726,RC00836,RC00837,RC01726 ko00000,ko00001,ko00002,ko01000 - - - IlvC,IlvN k141_21355_2 1002809.SSIL_0899 6.02e-61 202.0 COG0422@1|root,COG0422@2|Bacteria,1TNZ3@1239|Firmicutes,4HC0P@91061|Bacilli,26EPU@186818|Planococcaceae 91061|Bacilli H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction thiC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 ko:K03147 ko00730,ko01100,map00730,map01100 M00127 R03472 RC03251,RC03252 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU08790 ThiC-associated,ThiC_Rad_SAM k141_4741_1 1453501.JELR01000001_gene3198 8.68e-143 429.0 COG3240@1|root,COG3240@2|Bacteria,1RCCU@1224|Proteobacteria,1S2GX@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Phospholipase lecithinase hemolysin estA GO:0003674,GO:0003824,GO:0016289,GO:0016290,GO:0016787,GO:0016788,GO:0016790,GO:0047617,GO:0052689 - ko:K12686 - - - - ko00000,ko02000,ko02044 1.B.12.8 - - Autotransporter,Lipase_GDSL k141_4741_2 1279017.AQYJ01000022_gene2650 2.65e-243 673.0 COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RNN0@1236|Gammaproteobacteria,467I6@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0436 Aspartate tyrosine aromatic aminotransferase - - 2.6.1.1,2.6.1.84 ko:K00812,ko:K12252 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 - R00355,R00694,R00734,R00896,R02433,R02619,R05052,R08197 RC00006,RC00008 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 k141_4741_4 566466.NOR53_3405 3.19e-50 171.0 COG2370@1|root,COG2370@2|Bacteria,1MV6Z@1224|Proteobacteria,1RRHA@1236|Gammaproteobacteria,1J643@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O HupE / UreJ protein - - - - - - - - - - - - HupE_UreJ_2 k141_36656_1 1121918.ARWE01000001_gene1163 1e-27 114.0 COG0859@1|root,COG0859@2|Bacteria,1N6SN@1224|Proteobacteria 1224|Proteobacteria M Glycosyltransferase family 9 (heptosyltransferase) - - - - - - - - - - - - Glyco_transf_9 k141_16643_1 946235.CAER01000060_gene3342 3.42e-111 349.0 COG0553@1|root,COG4715@1|root,COG0553@2|Bacteria,COG4715@2|Bacteria,1TPFZ@1239|Firmicutes,4HAIF@91061|Bacilli,23IT1@182709|Oceanobacillus 91061|Bacilli L Bacterial SNF2 helicase associated snf - - - - - - - - - - - Helicase_C,SNF2_N,SNF2_assoc,SWIM k141_21356_2 1245471.PCA10_45600 9.13e-27 108.0 COG1024@1|root,COG1024@2|Bacteria,1PK10@1224|Proteobacteria,1RSCH@1236|Gammaproteobacteria 1236|Gammaproteobacteria I COG1024 Enoyl-CoA hydratase carnithine racemase - - 4.2.1.17 ko:K01692 ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212 M00032,M00087 R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093 RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 k141_28395_1 218284.CCDN010000004_gene3035 6.66e-123 360.0 COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,4HA95@91061|Bacilli,1ZCW9@1386|Bacillus 91061|Bacilli E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids alr - 5.1.1.1,5.1.1.5 ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 - R00401 RC00285 ko00000,ko00001,ko01000,ko01011 - - - Ala_racemase_C,Ala_racemase_N k141_8212_2 1347086.CCBA010000031_gene879 6.19e-12 64.3 COG0204@1|root,COG0204@2|Bacteria,1UMJA@1239|Firmicutes,4HD2E@91061|Bacilli,1ZEYG@1386|Bacillus 91061|Bacilli I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family ypkP - 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase k141_36720_1 580331.Thit_1434 4.83e-60 196.0 COG0182@1|root,COG0182@2|Bacteria,1TPDK@1239|Firmicutes,249C5@186801|Clostridia,42F9M@68295|Thermoanaerobacterales 186801|Clostridia J Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) mtnA - 5.3.1.23 ko:K08963 ko00270,ko01100,map00270,map01100 M00034 R04420 RC01151 ko00000,ko00001,ko00002,ko01000 - - - IF-2B k141_31814_1 1294265.JCM21738_3822 2.45e-76 236.0 COG2909@1|root,COG2909@2|Bacteria,1UIMV@1239|Firmicutes,4HD7H@91061|Bacilli,1ZSHA@1386|Bacillus 91061|Bacilli K helix_turn_helix, Lux Regulon - - - ko:K03556 - - - - ko00000,ko03000 - - - GerE k141_15355_1 1453501.JELR01000002_gene1395 6.69e-260 731.0 COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,COG3706@2|Bacteria,1PJCA@1224|Proteobacteria,1RS4H@1236|Gammaproteobacteria,4663N@72275|Alteromonadaceae 1236|Gammaproteobacteria T Putative diguanylate phosphodiesterase - - - ko:K21025 ko02025,map02025 - - - ko00000,ko00001 - - - EAL,GGDEF,PAS,PAS_8,PAS_9,Response_reg k141_31815_1 1340434.AXVA01000029_gene73 1.2e-99 296.0 28HCB@1|root,2Z7P7@2|Bacteria,1TNZK@1239|Firmicutes,4HBET@91061|Bacilli,1ZCTC@1386|Bacillus 91061|Bacilli S peptidase yabG GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0031160,GO:0043591,GO:0043593,GO:0044426,GO:0044462,GO:0044464,GO:0071944 - ko:K06436 - - - - ko00000 - - - Peptidase_U57 k141_15356_1 218284.CCDN010000007_gene3958 1.05e-143 412.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HAKV@91061|Bacilli,1ZPZN@1386|Bacillus 91061|Bacilli I acyl-CoA dehydrogenase acdA - 1.3.8.1,1.3.8.7 ko:K00248,ko:K00249 ko00071,ko00280,ko00410,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map00650,map01100,map01110,map01120,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01178,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00120,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_8215_1 1385514.N782_04275 1.18e-49 170.0 COG2340@1|root,COG2340@2|Bacteria,1V6FY@1239|Firmicutes,4HJ44@91061|Bacilli,2YA78@289201|Pontibacillus 91061|Bacilli S Cysteine-rich secretory protein family - - - - - - - - - - - - CAP k141_31816_1 1131553.JIBI01000019_gene470 1.38e-10 68.9 COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,2VJCZ@28216|Betaproteobacteria,372AE@32003|Nitrosomonadales 28216|Betaproteobacteria O Peptidyl-prolyl cis-trans isomerase ppiD - 5.2.1.8 ko:K03770 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_2,Rotamase_3,SurA_N_3 k141_15357_1 218284.CCDN010000001_gene527 1.78e-111 344.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,4H9S7@91061|Bacilli,1ZB6Y@1386|Bacillus 91061|Bacilli L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A k141_8216_1 1294265.JCM21738_4087 0.00032 40.4 COG0762@1|root,COG0762@2|Bacteria,1VEKA@1239|Firmicutes,4HNJR@91061|Bacilli,1ZHUZ@1386|Bacillus 91061|Bacilli S membrane ylmG - - ko:K02221 - - - - ko00000,ko02044 - - - YGGT k141_8216_2 997296.PB1_01485 1.33e-72 221.0 COG1799@1|root,COG1799@2|Bacteria,1VER3@1239|Firmicutes,4HKIC@91061|Bacilli,1ZGE0@1386|Bacillus 91061|Bacilli D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA sepF GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0022402,GO:0022607,GO:0032506,GO:0042802,GO:0044085,GO:0051301,GO:0071840,GO:0090529 - ko:K09772 - - - - ko00000,ko03036 - - - SepF k141_8216_3 1294265.JCM21738_4084 7.9e-35 124.0 COG0325@1|root,COG0325@2|Bacteria,1TRDN@1239|Firmicutes,4HC45@91061|Bacilli,1ZARM@1386|Bacillus 91061|Bacilli S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis ylmE GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 - ko:K06997 - - - - ko00000 - - - Ala_racemase_N k141_37981_2 223926.28805777 1.78e-189 535.0 COG1344@1|root,COG1344@2|Bacteria,1MV1N@1224|Proteobacteria,1RN0Y@1236|Gammaproteobacteria,1XUYS@135623|Vibrionales 135623|Vibrionales N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella - GO:0005575,GO:0005576,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 - - - ko00000,ko00001,ko02035 - - - Flagellin_C,Flagellin_IN,Flagellin_N k141_37981_3 945543.VIBR0546_09664 4.37e-112 322.0 COG2190@1|root,COG2190@2|Bacteria,1MWIQ@1224|Proteobacteria,1RNE3@1236|Gammaproteobacteria,1XT2S@135623|Vibrionales 135623|Vibrionales G COG2190 Phosphotransferase system IIA components crr - - ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 M00265,M00266,M00268,M00270,M00272,M00303,M00806 R02738,R02780,R04111,R04394,R05132,R08559 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.1 - - PTS_EIIA_1 k141_37981_4 1219076.N646_2940 0.0 1051.0 COG1080@1|root,COG1080@2|Bacteria,1MUT8@1224|Proteobacteria,1RN6R@1236|Gammaproteobacteria,1XSKW@135623|Vibrionales 135623|Vibrionales G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) ptsI - 2.7.3.9 ko:K08483 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 8.A.7 - - PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C k141_37981_5 1219076.N646_2941 6.04e-52 164.0 COG1925@1|root,COG1925@2|Bacteria,1N0CV@1224|Proteobacteria,1S9R2@1236|Gammaproteobacteria,1XXVH@135623|Vibrionales 135623|Vibrionales G phosphocarrier protein hpr ptsH GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0008150,GO:0008643,GO:0008982,GO:0009401,GO:0015144,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0051179,GO:0051234,GO:0055085,GO:0071702 - ko:K02784 ko02060,map02060 - - - ko00000,ko00001,ko02000 8.A.8.1.1 - - PTS-HPr k141_37981_6 223926.28805783 2.62e-214 593.0 COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,1RN6J@1236|Gammaproteobacteria,1XTGD@135623|Vibrionales 135623|Vibrionales E Belongs to the cysteine synthase cystathionine beta- synthase family cysK - 2.5.1.47 ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03601,R04859 RC00020,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 - - - PALP k141_37981_7 1116375.VEJY3_03625 2.88e-165 463.0 COG2981@1|root,COG2981@2|Bacteria,1MVFT@1224|Proteobacteria,1RMQT@1236|Gammaproteobacteria,1XTRY@135623|Vibrionales 135623|Vibrionales U High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway cysZ GO:0003674,GO:0005215 - ko:K06203 - - - - ko00000 - - - EI24 k141_37981_8 1116375.VEJY3_03630 2.48e-178 502.0 COG3115@1|root,COG3115@2|Bacteria,1MVHR@1224|Proteobacteria,1RMDB@1236|Gammaproteobacteria,1XSIV@135623|Vibrionales 135623|Vibrionales D Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins zipA - - ko:K03528 - - - - ko00000,ko03036 - - - ZipA_C k141_37981_9 1116375.VEJY3_03635 0.0 1249.0 COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,1RPAV@1236|Gammaproteobacteria,1XSJC@135623|Vibrionales 135623|Vibrionales L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA ligA GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360,GO:1901576 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - - BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5 k141_37981_10 1116375.VEJY3_03640 1.02e-312 854.0 2C471@1|root,2Z7J2@2|Bacteria,1NDEQ@1224|Proteobacteria,1RMG0@1236|Gammaproteobacteria,1XVDB@135623|Vibrionales 135623|Vibrionales S Outer membrane porin - - - - - - - - - - - - - k141_37981_11 1116375.VEJY3_03645 1.27e-67 206.0 2AWEE@1|root,31NAG@2|Bacteria,1QK1H@1224|Proteobacteria,1TI41@1236|Gammaproteobacteria,1XYBQ@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF2799) - - - - - - - - - - - - DUF2799 k141_37981_12 1116375.VEJY3_03650 2.5e-34 117.0 2BRPX@1|root,32KPI@2|Bacteria,1Q9SW@1224|Proteobacteria,1TK4N@1236|Gammaproteobacteria,1Y22H@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_37981_13 1116375.VEJY3_03655 1.02e-91 270.0 COG1585@1|root,COG1585@2|Bacteria,1N0CQ@1224|Proteobacteria,1SC5D@1236|Gammaproteobacteria,1XXC3@135623|Vibrionales 135623|Vibrionales OU COG1585 Membrane protein implicated in regulation of membrane protease activity - - - ko:K07340 - - - - ko00000 - - - NfeD k141_37981_14 1116375.VEJY3_03660 2.31e-158 451.0 COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,1RNW8@1236|Gammaproteobacteria,1XTTR@135623|Vibrionales 135623|Vibrionales O COG0330 Membrane protease subunits, stomatin prohibitin homologs qmcA - - - - - - - - - - - Band_7,Band_7_C k141_37981_15 1116375.VEJY3_03665 4.12e-192 534.0 COG3118@1|root,COG3118@2|Bacteria,1MV0R@1224|Proteobacteria,1RMSQ@1236|Gammaproteobacteria,1XST1@135623|Vibrionales 135623|Vibrionales O COG3118 Thioredoxin domain-containing protein ybbN - - ko:K05838 - - - - ko00000,ko03110 - - - TPR_19,TPR_20,Thioredoxin k141_37981_16 1116375.VEJY3_03670 7.86e-132 378.0 COG1028@1|root,COG1028@2|Bacteria,1MUCH@1224|Proteobacteria,1RNAA@1236|Gammaproteobacteria,1XTR2@135623|Vibrionales 135623|Vibrionales IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) ybbO - - - - - - - - - - - adh_short k141_28458_1 223926.28808746 6.6e-62 191.0 2C9B9@1|root,32RP0@2|Bacteria,1MZKM@1224|Proteobacteria,1S8UZ@1236|Gammaproteobacteria,1XXWT@135623|Vibrionales 135623|Vibrionales S HopJ type III effector protein - - - - - - - - - - - - HopJ k141_28458_2 1280001.BAOA01000058_gene4602 1.89e-60 186.0 COG3313@1|root,COG3313@2|Bacteria,1NGD5@1224|Proteobacteria,1TI4R@1236|Gammaproteobacteria,1XYDN@135623|Vibrionales 135623|Vibrionales S Cysteine-rich CWC RSC1457 - - - - - - - - - - - Cys_rich_CWC,DUF1289 k141_28458_3 1219076.N646_4579 1.31e-44 145.0 COG3530@1|root,COG3530@2|Bacteria,1N7GT@1224|Proteobacteria,1SCBX@1236|Gammaproteobacteria,1XYDT@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria STM2426 - - ko:K09954 - - - - ko00000 - - - QSregVF_b k141_28458_4 575788.VS_II0165 9.63e-41 135.0 2AWEF@1|root,31NAH@2|Bacteria,1QK1I@1224|Proteobacteria,1TI42@1236|Gammaproteobacteria,1XYBS@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_28458_5 1191299.AJYX01000009_gene210 1.21e-107 313.0 COG1238@1|root,COG1238@2|Bacteria,1MWED@1224|Proteobacteria,1S034@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Membrane - - - - - - - - - - - - SNARE_assoc k141_28458_6 484018.BACPLE_02908 5.49e-49 163.0 COG0664@1|root,COG0664@2|Bacteria,4NN9V@976|Bacteroidetes,2FSBK@200643|Bacteroidia,4AQTF@815|Bacteroidaceae 976|Bacteroidetes T Psort location Cytoplasmic, score 8.96 - - - - - - - - - - - - cNMP_binding k141_28458_7 391596.PBAL39_16671 1.63e-09 58.5 COG2084@1|root,COG2084@2|Bacteria,4NEF7@976|Bacteroidetes,1IS6B@117747|Sphingobacteriia 976|Bacteroidetes I PFAM 6-phosphogluconate dehydrogenase NAD-binding mmsB - 1.1.1.31,1.1.1.60 ko:K00020,ko:K00042 ko00280,ko00630,ko01100,map00280,map00630,map01100 - R01745,R01747,R05066 RC00099 ko00000,ko00001,ko01000 - - - NAD_binding_11,NAD_binding_2 k141_37982_1 880073.Calab_0822 8.18e-71 219.0 COG1435@1|root,COG1435@2|Bacteria,2NP88@2323|unclassified Bacteria 2|Bacteria F Thymidine kinase tdk GO:0003674,GO:0003824,GO:0004797,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R01567,R02099,R08233 RC00002,RC00017 ko00000,ko00001,ko01000 - - iLJ478.TM0401 TK k141_28459_1 1294265.JCM21738_3154 1.62e-118 347.0 COG1162@1|root,COG1162@2|Bacteria,1TP8Q@1239|Firmicutes,4H9PJ@91061|Bacilli,1ZCAI@1386|Bacillus 91061|Bacilli S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit rsgA_2 - 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 - R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 - - - RsgA_GTPase k141_30691_1 525919.Apre_0483 1.78e-14 71.2 COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,24QZQ@186801|Clostridia,22HYG@1570339|Peptoniphilaceae 186801|Clostridia J Binds together with S18 to 16S ribosomal RNA rpsF - - ko:K02990 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S6 k141_31819_3 218284.CCDN010000006_gene3511 5.11e-14 69.7 COG0300@1|root,COG0300@2|Bacteria,1UZHA@1239|Firmicutes,4HA3H@91061|Bacilli,1ZCKZ@1386|Bacillus 91061|Bacilli S Enoyl-(Acyl carrier protein) reductase - - - ko:K07124 - - - - ko00000 - - - adh_short k141_36724_1 218284.CCDN010000001_gene593 0.0 980.0 COG0470@1|root,COG1067@1|root,COG0470@2|Bacteria,COG1067@2|Bacteria,1TP2K@1239|Firmicutes,4HB6F@91061|Bacilli,1ZBW1@1386|Bacillus 91061|Bacilli LO Belongs to the peptidase S16 family lonB - 3.4.21.53 ko:K04076 - - - - ko00000,ko01000,ko01002 - - - AAA,Lon_C k141_36724_2 1196031.ALEG01000068_gene4826 3.34e-50 177.0 COG0466@1|root,COG0466@2|Bacteria,1TNYG@1239|Firmicutes,4HAZK@91061|Bacilli,1ZAXX@1386|Bacillus 91061|Bacilli O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner lon GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.4.21.53 ko:K01338 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - AAA,LON_substr_bdg,Lon_C k141_15359_1 218284.CCDN010000005_gene3206 4.02e-89 266.0 COG4565@1|root,COG4565@2|Bacteria,1V3PK@1239|Firmicutes,4HGXB@91061|Bacilli,1ZFRB@1386|Bacillus 91061|Bacilli T COG4565 Response regulator of citrate malate metabolism dcuR - - ko:K02475,ko:K11615 ko02020,map02020 M00490 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_11,Response_reg k141_8219_1 218284.CCDN010000002_gene2132 2.27e-116 347.0 COG1574@1|root,COG1574@2|Bacteria,1TQ6G@1239|Firmicutes,4H9T6@91061|Bacilli,1ZC1J@1386|Bacillus 91061|Bacilli S Amidohydrolase family ytcJ - - - - - - - - - - - Amidohydro_3 k141_28460_1 1453501.JELR01000001_gene3030 2.73e-108 342.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,464Y3@72275|Alteromonadaceae 1236|Gammaproteobacteria T GGDEF domain - - - - - - - - - - - - EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9 k141_36725_1 1453501.JELR01000001_gene1962 7.11e-20 87.4 COG4677@1|root,COG4677@2|Bacteria,1QBYN@1224|Proteobacteria,1RNSE@1236|Gammaproteobacteria,465VT@72275|Alteromonadaceae 1236|Gammaproteobacteria G Pectinesterase pemA GO:0005575,GO:0005576 3.1.1.11 ko:K01051 ko00040,ko01100,map00040,map01100 M00081 R02362 RC00460,RC00461 ko00000,ko00001,ko00002,ko01000 - - - Pectinesterase k141_36725_2 1095769.CAHF01000011_gene2167 2.8e-25 99.8 COG0789@1|root,COG0789@2|Bacteria,1RGX6@1224|Proteobacteria,2VSD1@28216|Betaproteobacteria,474GV@75682|Oxalobacteraceae 28216|Betaproteobacteria K helix_turn_helix, mercury resistance cueR - - ko:K19591 - M00769 - - ko00000,ko00002,ko01504,ko03000 - - - MerR,MerR-DNA-bind k141_37983_1 1279017.AQYJ01000028_gene2050 5.12e-41 145.0 COG3714@1|root,COG3714@2|Bacteria,1N6QN@1224|Proteobacteria,1SCQK@1236|Gammaproteobacteria,468R4@72275|Alteromonadaceae 1236|Gammaproteobacteria S YhhN family - - - - - - - - - - - - YhhN k141_8220_1 218284.CCDN010000001_gene878 2.2e-51 177.0 COG0840@1|root,COG0840@2|Bacteria,1UHRW@1239|Firmicutes,4IS7R@91061|Bacilli,1ZS21@1386|Bacillus 91061|Bacilli NT nuclear chromosome segregation - - - - - - - - - - - - Peptidase_S74 k141_31820_1 1121405.dsmv_0691 6.11e-154 452.0 COG5421@1|root,COG5421@2|Bacteria,1R3NX@1224|Proteobacteria,42QDV@68525|delta/epsilon subdivisions,2WIRQ@28221|Deltaproteobacteria,2MN1S@213118|Desulfobacterales 68525|delta/epsilon subdivisions L PFAM transposase IS4 family protein - - - - - - - - - - - - DDE_Tnp_1 k141_28463_1 218284.CCDN010000001_gene461 6.15e-91 281.0 COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,4HBUS@91061|Bacilli,1ZB01@1386|Bacillus 91061|Bacilli EH Belongs to the TPP enzyme family - - 1.2.3.3 ko:K00158 ko00620,ko01100,map00620,map01100 - R00207 RC02745 ko00000,ko00001,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N k141_8221_2 218284.CCDN010000001_gene1144 2.18e-34 122.0 COG5353@1|root,COG5353@2|Bacteria,1VA2H@1239|Firmicutes,4HNMM@91061|Bacilli,1ZFVJ@1386|Bacillus 91061|Bacilli S protein conserved in bacteria ypmB - - - - - - - - - - - PepSY k141_15362_1 1042377.AFPJ01000016_gene148 2.04e-87 265.0 28P60@1|root,2ZC0V@2|Bacteria,1RC8V@1224|Proteobacteria,1S29Y@1236|Gammaproteobacteria,46714@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF4194) - - - - - - - - - - - - DUF4194 k141_31821_1 218284.CCDN010000005_gene3223 4.74e-83 261.0 COG2206@1|root,COG2206@2|Bacteria,1UZN2@1239|Firmicutes,4HIY3@91061|Bacilli,1ZS2G@1386|Bacillus 91061|Bacilli T HD domain - - - - - - - - - - - - HD,HD_5 k141_8222_1 314285.KT71_19328 2.59e-88 269.0 COG1633@1|root,COG1633@2|Bacteria,1N5FH@1224|Proteobacteria,1SMBX@1236|Gammaproteobacteria,1J7MQ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) acsF - - - - - - - - - - - Rubrerythrin k141_31822_1 1294265.JCM21738_223 5.91e-80 245.0 COG2206@1|root,COG2206@2|Bacteria,1TR95@1239|Firmicutes,4HF2G@91061|Bacilli,1ZE39@1386|Bacillus 91061|Bacilli T HD domain - - - - - - - - - - - - HD,HD_5 k141_8223_1 1423144.Gal_03547 1.25e-52 171.0 COG3034@1|root,COG3034@2|Bacteria,1MXY6@1224|Proteobacteria,2TS2U@28211|Alphaproteobacteria,34FMT@302485|Phaeobacter 28211|Alphaproteobacteria S L,D-transpeptidase catalytic domain - - - - - - - - - - - - YkuD k141_37985_1 218284.CCDN010000001_gene144 6.69e-83 251.0 COG0483@1|root,COG0483@2|Bacteria,1TR4E@1239|Firmicutes,4HB92@91061|Bacilli,1ZAS1@1386|Bacillus 91061|Bacilli G Inositol monophosphatase suhB GO:0003674,GO:0003824,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 - - - Inositol_P k141_37985_3 218284.CCDN010000001_gene146 3.74e-122 351.0 COG4493@1|root,COG4493@2|Bacteria,1UY83@1239|Firmicutes,4HEDB@91061|Bacilli,1ZCEH@1386|Bacillus 91061|Bacilli S Belongs to the UPF0637 family yktB - - - - - - - - - - - DUF1054 k141_31824_1 218284.CCDN010000001_gene9 1.98e-161 459.0 COG0045@1|root,COG0045@2|Bacteria,1TQG4@1239|Firmicutes,4HA3W@91061|Bacilli,1ZB9P@1386|Bacillus 91061|Bacilli C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit sucC GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 6.2.1.5 ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU16090 ATP-grasp_2,Ligase_CoA k141_30698_1 1423321.AS29_06640 1.85e-30 115.0 COG2135@1|root,COG2135@2|Bacteria,1TRRV@1239|Firmicutes,4HDUN@91061|Bacilli,1ZCQB@1386|Bacillus 91061|Bacilli S Belongs to the SOS response-associated peptidase family yoqW - - - - - - - - - - - SRAP k141_30699_1 1123228.AUIH01000002_gene1641 2.82e-15 72.8 COG0765@1|root,COG0765@2|Bacteria,1QN80@1224|Proteobacteria,1S6MY@1236|Gammaproteobacteria,1XS47@135619|Oceanospirillales 135619|Oceanospirillales E Binding-protein-dependent transport system inner membrane component - - - - - - - - - - - - BPD_transp_1 k141_30699_2 1397528.Q671_07790 4.44e-63 199.0 COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,1RMX1@1236|Gammaproteobacteria,1XN5P@135619|Oceanospirillales 135619|Oceanospirillales E ATPases associated with a variety of cellular activities - - - - - - - - - - - - ABC_tran k141_37987_1 1294265.JCM21738_4749 4.11e-06 45.8 29SEG@1|root,30DJ8@2|Bacteria,1UBCJ@1239|Firmicutes,4IMRD@91061|Bacilli,1ZKP1@1386|Bacillus 91061|Bacilli S Spo0E like sporulation regulatory protein - - - ko:K06376 - - - - ko00000 - - - SpoOE-like k141_30700_1 218284.CCDN010000001_gene254 2.94e-12 64.3 COG1011@1|root,COG1011@2|Bacteria,1V2QW@1239|Firmicutes,4HG68@91061|Bacilli,1ZRBT@1386|Bacillus 91061|Bacilli S HAD-hyrolase-like - - - ko:K07025 - - - - ko00000 - - - HAD_2 k141_30700_2 1384049.CD29_15260 1.05e-65 203.0 COG3153@1|root,COG3153@2|Bacteria,1V6YN@1239|Firmicutes,4HKUT@91061|Bacilli 91061|Bacilli S acetyltransferase - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10 k141_8227_1 1294265.JCM21738_2885 2.85e-79 238.0 COG1559@1|root,COG1559@2|Bacteria,1VERY@1239|Firmicutes,4HPDX@91061|Bacilli,1ZB1P@1386|Bacillus 91061|Bacilli S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation yqzC - - - - - - - - - - - YceG k141_36726_1 717605.Theco_1796 9.96e-08 53.1 COG0388@1|root,COG0388@2|Bacteria,1TQDK@1239|Firmicutes,4HC44@91061|Bacilli,26QCB@186822|Paenibacillaceae 91061|Bacilli S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase mtnU - 3.5.1.3 ko:K13566 ko00250,map00250 - R00269,R00348 RC00010 ko00000,ko00001,ko01000 - - - CN_hydrolase k141_30824_2 218284.CCDN010000001_gene785 1.22e-135 384.0 COG0605@1|root,COG0605@2|Bacteria,1TPXT@1239|Firmicutes,4HA6U@91061|Bacilli,1ZBWK@1386|Bacillus 91061|Bacilli P radicals which are normally produced within the cells and which are toxic to biological systems sodA GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1 ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 - - - ko00000,ko00001,ko01000 - - - Sod_Fe_C,Sod_Fe_N k141_36811_1 218284.CCDN010000002_gene2684 1.17e-72 228.0 2BVD0@1|root,32QT1@2|Bacteria,1V3YR@1239|Firmicutes,4HIBT@91061|Bacilli,1ZJ6H@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_15454_1 218284.CCDN010000001_gene113 1.22e-53 169.0 2EG6V@1|root,339YR@2|Bacteria,1VPN6@1239|Firmicutes,4HREE@91061|Bacilli,1ZIWK@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_15454_2 218284.CCDN010000001_gene114 1.12e-45 150.0 COG3679@1|root,COG3679@2|Bacteria,1V3R6@1239|Firmicutes,4HGYS@91061|Bacilli,1ZG76@1386|Bacillus 91061|Bacilli S Belongs to the UPF0342 family ylbF - - - - - - - - - - - Com_YlbF k141_36812_2 1294265.JCM21738_1322 3.23e-80 240.0 2CC7N@1|root,3456K@2|Bacteria,1VZKA@1239|Firmicutes,4HZ9T@91061|Bacilli,1ZQKN@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_30826_2 1121923.GPUN_1216 1.64e-09 59.3 COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,1RQRP@1236|Gammaproteobacteria,4653Y@72275|Alteromonadaceae 1236|Gammaproteobacteria Q COG1228 Imidazolonepropionase and related amidohydrolases - - - - - - - - - - - - Amidohydro_1 k141_16804_4 223926.28807584 0.0 1164.0 COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,1RPFB@1236|Gammaproteobacteria,1XTJC@135623|Vibrionales 135623|Vibrionales M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner lepA GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03596 ko05134,map05134 - - - ko00000,ko00001 - - - EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C k141_16804_5 1219076.N646_1668 4.25e-90 266.0 COG3086@1|root,COG3086@2|Bacteria,1N6QS@1224|Proteobacteria,1SCTM@1236|Gammaproteobacteria,1XWZF@135623|Vibrionales 135623|Vibrionales T COG3086 Positive regulator of sigma E activity rseC - - ko:K03803 - - - - ko00000,ko03021 - - - RseC_MucC k141_22762_1 1121935.AQXX01000115_gene4992 5.28e-101 301.0 COG1063@1|root,COG1063@2|Bacteria,1MV9A@1224|Proteobacteria,1RMNY@1236|Gammaproteobacteria,1XIGQ@135619|Oceanospirillales 135619|Oceanospirillales C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate tdh - 1.1.1.103 ko:K00060 ko00260,map00260 - R01465 RC00525 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N k141_13282_1 1042377.AFPJ01000028_gene2229 7.08e-41 147.0 COG4324@1|root,COG4324@2|Bacteria,1N0FE@1224|Proteobacteria,1S0UK@1236|Gammaproteobacteria,46ACH@72275|Alteromonadaceae 1236|Gammaproteobacteria S Putative aminopeptidase - - - - - - - - - - - - Aminopep k141_257_1 1304888.ATWF01000002_gene448 1.26e-45 166.0 COG3808@1|root,COG3808@2|Bacteria,2GFAJ@200930|Deferribacteres 200930|Deferribacteres C Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane hppA - 3.6.1.1 ko:K15987 ko00190,map00190 - - - ko00000,ko00001,ko01000 3.A.10.1 - - H_PPase k141_12071_2 1123504.JQKD01000006_gene1535 4.41e-06 48.5 29CEM@1|root,2ZZD2@2|Bacteria,1RB3W@1224|Proteobacteria,2VT9S@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k141_8531_1 1294265.JCM21738_1460 3.91e-52 177.0 COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4HC58@91061|Bacilli,1ZB1Y@1386|Bacillus 91061|Bacilli S COG0488 ATPase components of ABC transporters with duplicated ATPase domains yfmM - - - - - - - - - - - ABC_tran,ABC_tran_Xtn k141_2581_2 223926.28809262 4.02e-199 553.0 COG0583@1|root,COG0583@2|Bacteria,1N4P5@1224|Proteobacteria,1RSQH@1236|Gammaproteobacteria,1XWJD@135623|Vibrionales 135623|Vibrionales K Bacterial regulatory helix-turn-helix protein, lysR family - - - - - - - - - - - - HTH_1,LysR_substrate k141_2581_3 223926.28809263 1.02e-172 484.0 COG1526@1|root,COG1526@2|Bacteria,1NRU0@1224|Proteobacteria,1RNFH@1236|Gammaproteobacteria,1XVCT@135623|Vibrionales 135623|Vibrionales C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH - - - ko:K02379 - - - - ko00000 - - - FdhD-NarQ k141_2581_4 223926.28809269 2.77e-261 721.0 COG1257@1|root,COG1257@2|Bacteria,1Q6M1@1224|Proteobacteria,1RPEP@1236|Gammaproteobacteria,1XTS2@135623|Vibrionales 135623|Vibrionales I reductase hmgA - 1.1.1.34 ko:K00021 ko00900,ko01100,ko01110,ko01130,ko04152,ko04976,map00900,map01100,map01110,map01130,map04152,map04976 M00095 R02082 RC00004,RC00644 ko00000,ko00001,ko00002,ko01000 - - - HMG-CoA_red k141_2581_5 223926.28809272 1.42e-246 679.0 COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,1RNIR@1236|Gammaproteobacteria,1XT0J@135623|Vibrionales 135623|Vibrionales I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids fabH2 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACP_syn_III,ACP_syn_III_C k141_2581_6 223926.28809273 1.42e-96 282.0 COG3118@1|root,COG3118@2|Bacteria,1RHUA@1224|Proteobacteria,1S64W@1236|Gammaproteobacteria,1XWV6@135623|Vibrionales 135623|Vibrionales O COG0526 Thiol-disulfide isomerase and thioredoxins trxC - 1.8.1.8 ko:K03672 - - - - ko00000,ko01000,ko03110 - - - Thioredoxin k141_2581_7 223926.28809274 1.3e-100 302.0 COG0738@1|root,COG0738@2|Bacteria,1QUEB@1224|Proteobacteria,1T1VW@1236|Gammaproteobacteria,1XT1X@135623|Vibrionales 135623|Vibrionales G of the major facilitator superfamily - - - - - - - - - - - - MFS_1,Sugar_tr k141_35803_1 1179773.BN6_14930 5.38e-06 51.6 COG1372@1|root,COG1702@1|root,COG1372@2|Bacteria,COG1702@2|Bacteria,2GK0W@201174|Actinobacteria,4DY9G@85010|Pseudonocardiales 201174|Actinobacteria T Phosphate starvation-inducible protein PhoH phoH GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K06217 - - - - ko00000 - - - PhoH k141_35803_2 1033734.CAET01000008_gene3491 0.0001 42.7 28VRR@1|root,2ZHTJ@2|Bacteria,1W6RM@1239|Firmicutes,4IFAF@91061|Bacilli,1ZITN@1386|Bacillus 91061|Bacilli S YozD-like protein yozD - - - - - - - - - - - YozD k141_21616_1 218284.CCDN010000001_gene539 5.64e-126 375.0 COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,4HABZ@91061|Bacilli,1ZB5W@1386|Bacillus 91061|Bacilli J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) thrS GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD k141_33441_1 1042377.AFPJ01000051_gene38 1.15e-77 244.0 COG0845@1|root,COG0845@2|Bacteria,1QTZQ@1224|Proteobacteria,1T1J7@1236|Gammaproteobacteria 1236|Gammaproteobacteria M HlyD family secretion protein - - - ko:K01993 - - - - ko00000 - - - Biotin_lipoyl_2,HlyD_3 k141_2582_1 1219035.NT2_07_00780 1.63e-11 63.5 COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,2U35B@28211|Alphaproteobacteria,2K2DV@204457|Sphingomonadales 204457|Sphingomonadales I Carboxyl transferase domain - - 6.4.1.4 ko:K01969 ko00280,ko01100,map00280,map01100 M00036 R04138 RC00367,RC00942 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans k141_2582_2 766499.C357_09727 2.59e-35 130.0 COG1028@1|root,COG1028@2|Bacteria,1PFUB@1224|Proteobacteria,2U149@28211|Alphaproteobacteria 28211|Alphaproteobacteria IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - ko:K13774 ko00281,map00281 - R08087,R08096,R10125,R10126 RC00080,RC00087 ko00000,ko00001 - - - adh_short_C2 k141_15676_2 1347368.HG964404_gene5339 1.67e-87 260.0 COG2320@1|root,COG2320@2|Bacteria,1V3IB@1239|Firmicutes,4HH5X@91061|Bacilli,1ZHJE@1386|Bacillus 91061|Bacilli K GrpB protein yqkA - - - - - - - - - - - Acetyltransf_10,GrpB k141_25117_1 218284.CCDN010000005_gene3349 4.87e-82 256.0 COG4108@1|root,COG4108@2|Bacteria,1TPYT@1239|Firmicutes,4HADS@91061|Bacilli,1ZBIP@1386|Bacillus 91061|Bacilli J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP prfC GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02837 - - - - ko00000,ko03012 - - - GTP_EFTU,GTP_EFTU_D2,RF3_C k141_25117_2 218284.CCDN010000005_gene3350 1.14e-130 382.0 COG2200@1|root,COG2200@2|Bacteria,1TQ94@1239|Firmicutes,4HAK1@91061|Bacilli,1ZPXF@1386|Bacillus 91061|Bacilli T Putative diguanylate phosphodiesterase M1-600 - - - - - - - - - - - EAL k141_10836_1 1453501.JELR01000001_gene1851 2.97e-106 324.0 COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,1RNYW@1236|Gammaproteobacteria,46415@72275|Alteromonadaceae 1236|Gammaproteobacteria OU COG0616 Periplasmic serine proteases (ClpP class) sppA GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0010467,GO:0016020,GO:0016021,GO:0016485,GO:0016787,GO:0019538,GO:0031224,GO:0031226,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 - ko:K04773 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S49 k141_7324_1 1219076.N646_2852 1.97e-134 392.0 COG1611@1|root,COG1611@2|Bacteria,1MVQJ@1224|Proteobacteria,1RQHX@1236|Gammaproteobacteria,1XVEP@135623|Vibrionales 135623|Vibrionales S Rossmann fold nucleotide-binding protein ygdH - 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - DUF3412,DUF4478,Lysine_decarbox k141_7324_2 223926.28805683 1.97e-63 199.0 COG0258@1|root,COG0258@2|Bacteria,1MX9Y@1224|Proteobacteria,1RQZE@1236|Gammaproteobacteria,1XTDZ@135623|Vibrionales 135623|Vibrionales L Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment xni GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006281,GO:0006308,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0033554,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575 - ko:K01146 - - - - ko00000 - - - 5_3_exonuc,5_3_exonuc_N k141_13284_2 1294265.JCM21738_2905 4.56e-39 130.0 2BX75@1|root,32YCI@2|Bacteria,1VEDY@1239|Firmicutes,4HNHZ@91061|Bacilli,1ZIWS@1386|Bacillus 91061|Bacilli S spore protein - - - ko:K06418,ko:K06419 - - - - ko00000 - - - SASP k141_23927_1 218284.CCDN010000001_gene687 9.82e-203 565.0 COG0502@1|root,COG0502@2|Bacteria,1TPQ4@1239|Firmicutes,4HAGM@91061|Bacilli,1ZCAU@1386|Bacillus 91061|Bacilli H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism bioB - 2.8.1.6 ko:K01012 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R01078 RC00441 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU30200 BATS,Radical_SAM k141_35804_1 1453501.JELR01000002_gene1439 2.25e-93 276.0 COG1695@1|root,COG1695@2|Bacteria,1MZYS@1224|Proteobacteria,1S9RS@1236|Gammaproteobacteria,46CW4@72275|Alteromonadaceae 1236|Gammaproteobacteria K Replication-relaxation aphA - - ko:K10917 ko02024,ko05111,map02024,map05111 - - - ko00000,ko00001,ko03000 - - - PadR,Vir_act_alpha_C k141_28773_1 218284.CCDN010000002_gene2882 3.87e-38 132.0 COG3764@1|root,COG3764@2|Bacteria,1V79B@1239|Firmicutes,4HJ8C@91061|Bacilli,1ZHDM@1386|Bacillus 91061|Bacilli M Sortase family - - - - - - - - - - - - Sortase k141_28773_2 218284.CCDN010000002_gene2883 8.05e-63 205.0 COG0737@1|root,COG0737@2|Bacteria,1TQCW@1239|Firmicutes,4HEVJ@91061|Bacilli,1ZM3P@1386|Bacillus 91061|Bacilli F 5'-nucleotidase, C-terminal domain - - - - - - - - - - - - 5_nucleotid_C,Metallophos k141_18074_1 1294265.JCM21738_4840 3.98e-166 464.0 COG0745@1|root,COG0745@2|Bacteria,1TPQG@1239|Firmicutes,4HA8Q@91061|Bacilli,1ZAT8@1386|Bacillus 91061|Bacilli T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain yycF GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K07668 ko02020,map02020 M00459 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C k141_36991_2 1042377.AFPJ01000010_gene1471 8.64e-139 394.0 COG0602@1|root,COG0602@2|Bacteria,1MUJ2@1224|Proteobacteria,1RNQZ@1236|Gammaproteobacteria,464EB@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds queE - 4.3.99.3 ko:K10026 ko00790,ko01100,map00790,map01100 - R10002 RC02989 ko00000,ko00001,ko01000,ko03016 - - - Fer4_14,Radical_SAM k141_36991_3 1279017.AQYJ01000022_gene2673 5.71e-95 288.0 COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,1RQWA@1236|Gammaproteobacteria,467MP@72275|Alteromonadaceae 1236|Gammaproteobacteria D Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division cpoB GO:0005575,GO:0005623,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043933,GO:0044085,GO:0044464,GO:0051259,GO:0051260,GO:0051301,GO:0065003,GO:0071840 - - - - - - - - - - TPR_16,TPR_6,TolA_bind_tri k141_260_1 42565.FP66_09010 3.74e-106 319.0 COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,1RN3R@1236|Gammaproteobacteria,1XHH7@135619|Oceanospirillales 135619|Oceanospirillales J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) gltX - 6.1.1.17 ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 - - - tRNA-synt_1c k141_25118_1 1196031.ALEG01000008_gene4996 1.2e-73 227.0 COG4359@1|root,COG4359@2|Bacteria,1V1V0@1239|Firmicutes,4HC1U@91061|Bacilli,1ZEJT@1386|Bacillus 91061|Bacilli E conserved protein, possibly involved in methylthioadenosine recycling - - - - - - - - - - - - HAD,Put_Phosphatase k141_19172_1 349521.HCH_03018 1.04e-47 175.0 COG1538@1|root,COG1538@2|Bacteria,1NW1T@1224|Proteobacteria,1RPGN@1236|Gammaproteobacteria,1XHHM@135619|Oceanospirillales 135619|Oceanospirillales MU Outer membrane efflux protein - - - - - - - - - - - - OEP k141_22763_1 218284.CCDN010000001_gene946 7.47e-229 652.0 COG0209@1|root,COG0209@2|Bacteria,1TPFH@1239|Firmicutes,4HA07@91061|Bacilli,1ZCST@1386|Bacillus 91061|Bacilli F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen nrdZ - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_lgC,Ribonuc_red_lgN k141_23928_1 420324.KI912067_gene6539 6.85e-71 225.0 COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TV0Z@28211|Alphaproteobacteria,1JX2B@119045|Methylobacteriaceae 28211|Alphaproteobacteria P ATPases associated with a variety of cellular activities - - - ko:K10112 ko02010,map02010 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1 - - ABC_tran,TOBE_2 k141_3791_1 1196324.A374_17099 3.4e-05 43.1 2EFR8@1|root,339HA@2|Bacteria,1VHR4@1239|Firmicutes,4HQMM@91061|Bacilli 91061|Bacilli - - yocN - - - - - - - - - - - - k141_3791_2 1121091.AUMP01000021_gene3211 4.53e-31 111.0 2EHWS@1|root,33BND@2|Bacteria,1VPU6@1239|Firmicutes,4HRS1@91061|Bacilli 91061|Bacilli - - yozN - - - - - - - - - - - - k141_15677_1 218284.CCDN010000001_gene573 2.81e-198 562.0 COG0322@1|root,COG0322@2|Bacteria,1TP4B@1239|Firmicutes,4H9QH@91061|Bacilli,1ZBY1@1386|Bacillus 91061|Bacilli L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision uvrC - - ko:K03703 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N k141_21617_1 1042377.AFPJ01000024_gene783 4.69e-44 157.0 COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,4662Z@72275|Alteromonadaceae 1236|Gammaproteobacteria NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB gspE - - ko:K02454 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSE,T2SSE_N k141_31124_2 1042377.AFPJ01000034_gene2413 3.82e-25 96.3 COG2841@1|root,COG2841@2|Bacteria,1NGDM@1224|Proteobacteria,1TB3I@1236|Gammaproteobacteria,46BU7@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF465) - - - ko:K09794 - - - - ko00000 - - - DUF465 k141_31124_3 1117318.PRUB_12921 2.12e-109 320.0 COG3806@1|root,COG3806@2|Bacteria,1R52I@1224|Proteobacteria,1RNI5@1236|Gammaproteobacteria,2Q1HG@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria T COG3806 Anti-sigma factor - - - - - - - - - - - - Cupin_7 k141_6207_1 1279017.AQYJ01000028_gene2268 0.0 988.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MWTT@1224|Proteobacteria,1RP0H@1236|Gammaproteobacteria,46CKB@72275|Alteromonadaceae 1236|Gammaproteobacteria P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec k141_6207_2 1279017.AQYJ01000028_gene2269 5.34e-295 811.0 COG0654@1|root,COG0654@2|Bacteria,1NSGN@1224|Proteobacteria,1T22A@1236|Gammaproteobacteria,46505@72275|Alteromonadaceae 1236|Gammaproteobacteria CH Tryptophan halogenase - - - - - - - - - - - - Trp_halogenase k141_34655_1 1279017.AQYJ01000022_gene2692 1.85e-31 112.0 2EJQP@1|root,33DFH@2|Bacteria,1NI6C@1224|Proteobacteria,1SHDR@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Specific class of high-redox-potential 4Fe-4S ferredoxins. Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria - - - - - - - - - - - - HIPIP k141_34655_5 1279017.AQYJ01000022_gene2686 2.3e-261 732.0 COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,1RNPT@1236|Gammaproteobacteria,464DV@72275|Alteromonadaceae 1236|Gammaproteobacteria C The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) aceF - 2.3.1.12 ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding k141_34655_6 1042377.AFPJ01000010_gene1462 0.0 1710.0 COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,1RN6K@1236|Gammaproteobacteria,464NI@72275|Alteromonadaceae 1236|Gammaproteobacteria C Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) aceE - 1.2.4.1 ko:K00163 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_0339 Transketolase_N k141_34655_7 330214.NIDE0940 2.02e-47 161.0 COG3764@1|root,COG3764@2|Bacteria 2|Bacteria M Sortase family srtA - 3.4.22.70 ko:K07284 - - - - ko00000,ko01000,ko01002,ko01011 - - - Sortase k141_34655_8 1279017.AQYJ01000022_gene2683 1.6e-316 890.0 COG2304@1|root,COG2304@2|Bacteria,1MW8K@1224|Proteobacteria,1RNU3@1236|Gammaproteobacteria,46676@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein containing a von Willebrand factor type A (vWA) domain - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - VIT,VWA_3 k141_34655_9 1279017.AQYJ01000022_gene2682 2.48e-237 655.0 COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,1RNNY@1236|Gammaproteobacteria,4661A@72275|Alteromonadaceae 1236|Gammaproteobacteria F SAICAR synthetase purC GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04591 RC00064,RC00162 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b2476,iB21_1397.B21_02330,iBWG_1329.BWG_2240,iE2348C_1286.E2348C_2713,iEC042_1314.EC042_2677,iEC55989_1330.EC55989_2759,iECABU_c1320.ECABU_c27880,iECBD_1354.ECBD_1213,iECB_1328.ECB_02368,iECDH10B_1368.ECDH10B_2642,iECDH1ME8569_1439.ECDH1ME8569_2402,iECDH1ME8569_1439.EcDH1_1193,iECD_1391.ECD_02368,iECED1_1282.ECED1_2911,iECH74115_1262.ECH74115_3698,iECIAI1_1343.ECIAI1_2527,iECNA114_1301.ECNA114_2561,iECO103_1326.ECO103_2988,iECO111_1330.ECO111_3199,iECO26_1355.ECO26_3522,iECOK1_1307.ECOK1_2784,iECP_1309.ECP_2490,iECS88_1305.ECS88_2658,iECSE_1348.ECSE_2760,iECSF_1327.ECSF_2329,iECSP_1301.ECSP_3415,iECUMN_1333.ECUMN_2789,iECW_1372.ECW_m2698,iECs_1301.ECs3338,iEKO11_1354.EKO11_1259,iETEC_1333.ETEC_2581,iEcDH1_1363.EcDH1_1193,iEcE24377_1341.EcE24377A_2757,iEcHS_1320.EcHS_A2607,iEcSMS35_1347.EcSMS35_2623,iEcolC_1368.EcolC_1200,iG2583_1286.G2583_2999,iJN746.PP_1240,iJO1366.b2476,iJR904.b2476,iLF82_1304.LF82_1775,iNRG857_1313.NRG857_12360,iSFV_1184.SFV_2521,iSF_1195.SF2519,iSFxv_1172.SFxv_2773,iS_1188.S2669,iSbBS512_1146.SbBS512_E2848,iUMNK88_1353.UMNK88_3071,iWFL_1372.ECW_m2698,iY75_1357.Y75_RS12925,iYL1228.KPN_02810,iZ_1308.Z3735 SAICAR_synt k141_34655_10 1279017.AQYJ01000022_gene2681 7.83e-175 498.0 COG0628@1|root,COG0628@2|Bacteria,1MW0B@1224|Proteobacteria,1RPVP@1236|Gammaproteobacteria,465AI@72275|Alteromonadaceae 1236|Gammaproteobacteria S permease perM GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - ko:K03548 - - - - ko00000,ko02000 2.A.86.1 - - AI-2E_transport k141_34655_11 1279017.AQYJ01000022_gene2680 1.55e-23 92.8 COG0425@1|root,COG0425@2|Bacteria,1MZA5@1224|Proteobacteria,1SH3F@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Belongs to the sulfur carrier protein TusA family - - - ko:K04085 ko04122,map04122 - - - ko00000,ko00001,ko01000,ko03016 - - - TusA k141_34655_13 1279017.AQYJ01000022_gene2678 7.54e-224 620.0 COG0379@1|root,COG0379@2|Bacteria,1MWQU@1224|Proteobacteria,1RMFS@1236|Gammaproteobacteria,465WP@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate nadA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 ko:K03517 ko00760,ko01100,map00760,map01100 M00115 R04292 RC01119 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b0750,iAPECO1_1312.APECO1_1338,iB21_1397.B21_00692,iBWG_1329.BWG_0602,iECBD_1354.ECBD_2917,iECB_1328.ECB_00703,iECDH10B_1368.ECDH10B_0817,iECDH1ME8569_1439.ECDH1ME8569_0703,iECD_1391.ECD_00703,iECED1_1282.ECED1_0711,iECOK1_1307.ECOK1_0750,iECP_1309.ECP_0761,iECS88_1305.ECS88_0766,iECSP_1301.ECSP_0802,iECs_1301.ECs0778,iETEC_1333.ETEC_0754,iEcDH1_1363.EcDH1_2892,iEcolC_1368.EcolC_2912,iJN746.PP_1231,iJO1366.b0750,iJR904.b0750,iUMN146_1321.UM146_13905,iUTI89_1310.UTI89_C0747,iY75_1357.Y75_RS03905,iZ_1308.Z0919 NadA k141_261_1 1042377.AFPJ01000029_gene536 6.27e-57 193.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,4642R@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains pilR - - ko:K02481,ko:K02667 ko02020,map02020 M00501 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - HTH_8,Response_reg,Sigma54_activat k141_35805_1 1042377.AFPJ01000004_gene406 9.7e-74 244.0 COG1629@1|root,COG4771@2|Bacteria,1MUWN@1224|Proteobacteria,1RN1E@1236|Gammaproteobacteria,464FG@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec k141_2584_1 1196324.A374_08714 3.29e-39 150.0 COG0739@1|root,COG5280@1|root,COG5412@1|root,COG0739@2|Bacteria,COG5280@2|Bacteria,COG5412@2|Bacteria,1TQ28@1239|Firmicutes,4IUGP@91061|Bacilli 91061|Bacilli M Phage tail tape measure protein, TP901 family - - - - - - - - - - - - - k141_31157_1 1470593.BW43_05186 1.17e-43 145.0 2DN9I@1|root,32W8Y@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k141_28779_2 1121938.AUDY01000016_gene3010 6.97e-25 100.0 COG2340@1|root,COG2340@2|Bacteria,1V6FY@1239|Firmicutes,4HJ44@91061|Bacilli,3NEVQ@45667|Halobacillus 91061|Bacilli S Cysteine-rich secretory protein family - - - - - - - - - - - - CAP k141_6243_1 1348635.BBJY01000003_gene3775 2.81e-19 85.9 COG1653@1|root,COG1653@2|Bacteria,1MVGS@1224|Proteobacteria,1RQFU@1236|Gammaproteobacteria,1XUX4@135623|Vibrionales 135623|Vibrionales G Bacterial extracellular solute-binding protein - - - - - - - - - - - - SBP_bac_8 k141_3809_1 1294265.JCM21738_2362 5.46e-121 352.0 COG1680@1|root,COG1680@2|Bacteria,1TRR5@1239|Firmicutes,4HAZF@91061|Bacilli,1ZDIA@1386|Bacillus 91061|Bacilli V COG1680 Beta-lactamase class C and other penicillin binding proteins - - - - - - - - - - - - Beta-lactamase k141_1354_1 218284.CCDN010000001_gene1 4.4e-47 157.0 COG4465@1|root,COG4465@2|Bacteria,1TS7A@1239|Firmicutes,4HA9U@91061|Bacilli,1ZBT9@1386|Bacillus 91061|Bacilli K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor codY GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0044424,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - ko:K03706 - - - - ko00000,ko03000 - - - CodY,HTH_CodY k141_1354_2 218284.CCDN010000001_gene2 1.59e-259 719.0 COG1220@1|root,COG1220@2|Bacteria,1TPKQ@1239|Firmicutes,4HA83@91061|Bacilli,1ZCWK@1386|Bacillus 91061|Bacilli O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis hslU - - ko:K03667 - - - - ko00000,ko03110 - - - AAA_2,ClpB_D2-small k141_29879_1 926569.ANT_22440 2.94e-14 78.2 COG0760@1|root,COG0760@2|Bacteria,2G6RV@200795|Chloroflexi 200795|Chloroflexi O PFAM PpiC-type peptidyl-prolyl cis-trans isomerase - - - - - - - - - - - - Rotamase,Rotamase_3,SurA_N_3 k141_26411_1 218284.CCDN010000005_gene3254 2.5e-120 354.0 COG0446@1|root,COG0446@2|Bacteria,1TPWW@1239|Firmicutes,4HA11@91061|Bacilli,1ZATE@1386|Bacillus 91061|Bacilli P Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain cdr - 1.8.1.14 ko:K08255 - - - - ko00000,ko01000 - - - Pyr_redox_2,Pyr_redox_dim,Rhodanese,TusA k141_4930_1 94122.Shewana3_2703 4.12e-36 140.0 COG1629@1|root,COG1629@2|Bacteria,1MV8W@1224|Proteobacteria,1RMQA@1236|Gammaproteobacteria,2QA6Z@267890|Shewanellaceae 1236|Gammaproteobacteria M TonB-dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec k141_33465_1 42565.FP66_11125 2.16e-26 100.0 2CQ1K@1|root,32TEQ@2|Bacteria,1N3PX@1224|Proteobacteria,1T00Y@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Tripartite tricarboxylate transporter TctB family - - - ko:K07794 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.80.1 - - TctB k141_33465_2 42565.FP66_11130 3.39e-70 219.0 COG3181@1|root,COG3181@2|Bacteria,1MXEX@1224|Proteobacteria,1RPKH@1236|Gammaproteobacteria,1XNU3@135619|Oceanospirillales 135619|Oceanospirillales S Tripartite tricarboxylate transporter family receptor - - - ko:K07795 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.80.1 - - TctC k141_23960_1 218284.CCDN010000001_gene691 2.89e-08 50.8 COG4472@1|root,COG4472@2|Bacteria,1VAC4@1239|Firmicutes,4HKD0@91061|Bacilli,1ZHU7@1386|Bacillus 91061|Bacilli S Belongs to the UPF0297 family yrzL - - - - - - - - - - - DUF965 k141_20350_1 1279017.AQYJ01000021_gene2790 3.5e-105 304.0 COG1522@1|root,COG1522@2|Bacteria,1MX7R@1224|Proteobacteria,1RPGA@1236|Gammaproteobacteria,464VB@72275|Alteromonadaceae 1236|Gammaproteobacteria K transcriptional lrp - - ko:K03719 - - - - ko00000,ko03000,ko03036 - - - AsnC_trans_reg,HTH_24,HTH_AsnC-type k141_3810_1 218284.CCDN010000007_gene3785 2.96e-08 54.7 COG2206@1|root,COG2206@2|Bacteria,1TR95@1239|Firmicutes,4HB8S@91061|Bacilli,1ZCD6@1386|Bacillus 91061|Bacilli T HD domain M1-161 - - - - - - - - - - - HD,HD_5 k141_26412_1 1397528.Q671_07780 1.45e-82 248.0 COG0765@1|root,COG0765@2|Bacteria,1QN80@1224|Proteobacteria,1RR3B@1236|Gammaproteobacteria,1XN02@135619|Oceanospirillales 135619|Oceanospirillales E Binding-protein-dependent transport system inner membrane component - - - - - - - - - - - - BPD_transp_1 k141_31159_1 218284.CCDN010000002_gene2646 2.01e-78 253.0 COG1762@1|root,COG3711@1|root,COG1762@2|Bacteria,COG3711@2|Bacteria,1TQT1@1239|Firmicutes,4H9N4@91061|Bacilli,1ZBCM@1386|Bacillus 91061|Bacilli GKT COG3711 Transcriptional antiterminator - - 2.7.1.194 ko:K02821 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 M00283,M00550 R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.7.1 - - HTH_11,Mga,PRD,PTS_EIIA_2,PTS_IIB k141_16829_1 1116375.VEJY3_10715 7.01e-112 323.0 COG0424@1|root,COG0424@2|Bacteria,1RDA9@1224|Proteobacteria,1S3TQ@1236|Gammaproteobacteria,1XUK8@135623|Vibrionales 135623|Vibrionales D COG0424 Nucleotide-binding protein implicated in inhibition of septum formation yceF - - - - - - - - - - - Maf k141_1355_1 218284.CCDN010000001_gene530 3e-98 290.0 COG0237@1|root,COG0237@2|Bacteria,1V6FS@1239|Firmicutes,4HII3@91061|Bacilli,1ZFSI@1386|Bacillus 91061|Bacilli F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A coaE GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 ko:K00859 ko00770,ko01100,map00770,map01100 M00120 R00130 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS08510 CoaE k141_25162_1 574376.BAMA_09820 3.27e-36 135.0 28PM4@1|root,2ZCA8@2|Bacteria,1V1PA@1239|Firmicutes,4HFNN@91061|Bacilli,1ZG8T@1386|Bacillus 91061|Bacilli S YtkA-like - - - - - - - - - - - - YtkA k141_26413_1 1294265.JCM21738_4842 3.44e-108 324.0 COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HA52@91061|Bacilli,1ZCQI@1386|Bacillus 91061|Bacilli T Histidine kinase vicK - 2.7.13.3 ko:K07652 ko02020,map02020 M00459 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,PAS,PAS_9 k141_10863_1 1294265.JCM21738_327 1.08e-150 442.0 COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1TPMS@1239|Firmicutes,4HAQD@91061|Bacilli,1ZATW@1386|Bacillus 91061|Bacilli NT COG0643 Chemotaxis protein histidine kinase and related kinases cheA - 2.7.13.3 ko:K03407 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt,P2 k141_10863_2 796606.BMMGA3_06220 4.02e-25 102.0 COG2201@1|root,COG2201@2|Bacteria,1TRHC@1239|Firmicutes,4HBJY@91061|Bacilli,1ZC36@1386|Bacillus 91061|Bacilli NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR cheB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.1.1.61,3.5.1.44 ko:K03412 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 - - - CheB_methylest,Response_reg k141_23961_1 935261.JAGL01000019_gene582 4.76e-16 82.0 COG1597@1|root,COG1597@2|Bacteria,1RDWN@1224|Proteobacteria,2U7VI@28211|Alphaproteobacteria,43JFD@69277|Phyllobacteriaceae 28211|Alphaproteobacteria I Diacylglycerol kinase catalytic domain bmrU - - - - - - - - - - - DAGK_cat k141_23961_2 1453501.JELR01000001_gene2582 2.2e-09 55.8 COG3313@1|root,COG3313@2|Bacteria,1N711@1224|Proteobacteria,1S5BC@1236|Gammaproteobacteria,467HV@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF1289) - - - ko:K06938 - - - - ko00000 - - - DUF1289 k141_6245_1 218284.CCDN010000001_gene300 1.03e-131 383.0 COG2508@1|root,COG2508@2|Bacteria,1TRRH@1239|Firmicutes,4HDGP@91061|Bacilli,1ZB6S@1386|Bacillus 91061|Bacilli QT Transcriptional regulator yukF GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032502,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043934,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - - - - - - - - - - CodY,HTH_30 k141_5115_8 1042377.AFPJ01000007_gene1747 5.77e-111 324.0 COG1309@1|root,COG1309@2|Bacteria,1NM93@1224|Proteobacteria,1S56I@1236|Gammaproteobacteria,46DG9@72275|Alteromonadaceae 1236|Gammaproteobacteria K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N k141_5115_9 1042377.AFPJ01000007_gene1746 0.0 1132.0 COG4774@1|root,COG4774@2|Bacteria,1MX2G@1224|Proteobacteria,1SZI4@1236|Gammaproteobacteria 1236|Gammaproteobacteria P TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_5115_10 1042377.AFPJ01000007_gene1745 3.55e-269 742.0 COG0665@1|root,COG0665@2|Bacteria,1MVGP@1224|Proteobacteria,1RNJ9@1236|Gammaproteobacteria,464Z5@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0665 Glycine D-amino acid oxidases (deaminating) ordL GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0044424,GO:0044464,GO:0055114 - ko:K09471 ko00330,ko01100,map00330,map01100 M00136 R07415 RC00062 ko00000,ko00001,ko00002,ko01000 - - - DAO k141_5115_11 1453501.JELR01000001_gene2273 7.74e-312 850.0 COG0174@1|root,COG0174@2|Bacteria,1MU6V@1224|Proteobacteria,1RPNZ@1236|Gammaproteobacteria,46529@72275|Alteromonadaceae 1236|Gammaproteobacteria E Glutamine synthetase, catalytic domain spuB - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C k141_5115_12 1453501.JELR01000001_gene2272 0.0 981.0 COG1115@1|root,COG1115@2|Bacteria,1MUI3@1224|Proteobacteria,1RMNF@1236|Gammaproteobacteria,464Z4@72275|Alteromonadaceae 1236|Gammaproteobacteria E alanine symporter dagA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03310 - - - - ko00000 2.A.25 - - Na_Ala_symp k141_5115_13 1279017.AQYJ01000029_gene3793 5.35e-162 462.0 COG2515@1|root,COG2515@2|Bacteria,1MVYF@1224|Proteobacteria,1RMYP@1236|Gammaproteobacteria,4670H@72275|Alteromonadaceae 1236|Gammaproteobacteria E Pyridoxal-phosphate dependent enzyme - - 4.4.1.15 ko:K05396 ko00270,map00270 - R01874 RC00382 ko00000,ko00001,ko01000 - - - PALP k141_5115_14 1279017.AQYJ01000029_gene3792 5.87e-66 201.0 COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,1S9NV@1236|Gammaproteobacteria,467BH@72275|Alteromonadaceae 1236|Gammaproteobacteria U Preprotein translocase subunit YajC yajC GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031522,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - YajC k141_5115_15 1453501.JELR01000001_gene2269 8.86e-95 277.0 COG2207@1|root,COG2207@2|Bacteria,1RD5J@1224|Proteobacteria,1SYND@1236|Gammaproteobacteria,467VH@72275|Alteromonadaceae 1236|Gammaproteobacteria K helix_turn_helix, arabinose operon control protein - - - - - - - - - - - - Arabinose_bd,HTH_18 k141_5115_16 1453501.JELR01000001_gene2268 1.23e-99 290.0 COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,1RQ7F@1236|Gammaproteobacteria,4670Z@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG1225 Peroxiredoxin bcp GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016667,GO:0016671,GO:0016684,GO:0032843,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 ko:K03564 - - - - ko00000,ko01000 - - iPC815.YPO3064 AhpC-TSA k141_5115_17 1279017.AQYJ01000029_gene3788 5.41e-85 255.0 COG5488@1|root,COG5488@2|Bacteria 2|Bacteria S Integral membrane protein (DUF2244) - - - - - - - - - - - - DUF2244 k141_5115_18 1279017.AQYJ01000029_gene3787 3.89e-218 603.0 COG0039@1|root,COG0039@2|Bacteria,1MV57@1224|Proteobacteria,1RMAX@1236|Gammaproteobacteria,463ZA@72275|Alteromonadaceae 1236|Gammaproteobacteria C Catalyzes the reversible oxidation of malate to oxaloacetate mdh GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006107,GO:0006108,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019362,GO:0019637,GO:0019674,GO:0019752,GO:0030060,GO:0034641,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072350,GO:0072524,GO:1901360,GO:1901564 1.1.1.37 ko:K00024 ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740 R00342,R07136 RC00031 ko00000,ko00001,ko00002,ko01000 - - - Ldh_1_C,Ldh_1_N k141_5115_19 1279017.AQYJ01000029_gene3786 5.22e-116 335.0 COG4508@1|root,COG4508@2|Bacteria,1RAX1@1224|Proteobacteria,1RYFG@1236|Gammaproteobacteria,465HS@72275|Alteromonadaceae 1236|Gammaproteobacteria S dUTPase dut - - - - - - - - - - - dUTPase_2 k141_5115_20 1042377.AFPJ01000009_gene167 4.57e-161 454.0 COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,1RP6E@1236|Gammaproteobacteria,464EP@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG0084 Mg-dependent DNase ycfH GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase k141_5115_21 1453501.JELR01000001_gene2231 5.69e-74 222.0 COG3215@1|root,COG3215@2|Bacteria,1RGWZ@1224|Proteobacteria,1S4YE@1236|Gammaproteobacteria,467AW@72275|Alteromonadaceae 1236|Gammaproteobacteria NU COG3215 Tfp pilus assembly protein PilZ pilZ - - ko:K02676 - - - - ko00000,ko02035,ko02044 - - - PilZ k141_5115_22 1453501.JELR01000001_gene2230 3.97e-166 473.0 COG0470@1|root,COG0470@2|Bacteria,1MY1W@1224|Proteobacteria,1RNYA@1236|Gammaproteobacteria,466TQ@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG0470 ATPase involved in DNA replication holB GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNApol3-delta_C k141_5115_23 1279017.AQYJ01000029_gene3782 8.99e-105 307.0 COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,1S26C@1236|Gammaproteobacteria,466N6@72275|Alteromonadaceae 1236|Gammaproteobacteria F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis tmk GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 ko:K00943 ko00240,ko01100,map00240,map01100 M00053 R02094,R02098 RC00002 ko00000,ko00001,ko00002,ko01000 - - iECABU_c1320.ECABU_c13120,ic_1306.c1370 Thymidylate_kin k141_5115_24 1279017.AQYJ01000029_gene3781 8.23e-169 481.0 COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,1RMWD@1236|Gammaproteobacteria,4650E@72275|Alteromonadaceae 1236|Gammaproteobacteria S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation mltG GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006807,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0030203,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0042597,GO:0043170,GO:0044425,GO:0044459,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901564 - ko:K07082 - - - - ko00000 - - - YceG k141_5115_25 1042377.AFPJ01000009_gene172 5.36e-38 141.0 COG0115@1|root,COG0115@2|Bacteria 2|Bacteria E branched-chain-amino-acid transaminase activity pabB - 2.6.1.85,4.1.3.38 ko:K02619,ko:K03342 ko00790,map00790 - R01716,R05553 RC00010,RC01418,RC01843,RC02148 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_4,Chorismate_bind k141_5115_26 1042377.AFPJ01000009_gene173 1.61e-246 682.0 COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria,463YA@72275|Alteromonadaceae 1236|Gammaproteobacteria I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP fabF GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033817,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.179 ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - iAF1260.b1095,iAPECO1_1312.APECO1_176,iB21_1397.B21_01099,iBWG_1329.BWG_0943,iE2348C_1286.E2348C_1187,iEC042_1314.EC042_1165,iEC55989_1330.EC55989_1207,iECABU_c1320.ECABU_c13085,iECBD_1354.ECBD_2506,iECB_1328.ECB_01091,iECDH10B_1368.ECDH10B_1167,iECDH1ME8569_1439.ECDH1ME8569_1030,iECD_1391.ECD_01091,iECED1_1282.ECED1_1238,iECH74115_1262.ECH74115_1474,iECIAI1_1343.ECIAI1_1130,iECIAI39_1322.ECIAI39_2066,iECO103_1326.ECO103_1140,iECO111_1330.ECO111_1372,iECO26_1355.ECO26_1428,iECOK1_1307.ECOK1_1202,iECP_1309.ECP_1087,iECS88_1305.ECS88_1109,iECSE_1348.ECSE_1159,iECSF_1327.ECSF_0994,iECSP_1301.ECSP_1396,iECUMN_1333.ECUMN_1270,iECW_1372.ECW_m1203,iECs_1301.ECs1473,iEKO11_1354.EKO11_2739,iETEC_1333.ETEC_1160,iEcDH1_1363.EcDH1_2552,iEcE24377_1341.EcE24377A_1216,iEcSMS35_1347.EcSMS35_2032,iG2583_1286.G2583_1355,iJO1366.b1095,iJR904.b1095,iLF82_1304.LF82_0607,iNRG857_1313.NRG857_05280,iSF_1195.SF1099,iSFxv_1172.SFxv_1251,iS_1188.S1179,iUMN146_1321.UM146_11850,iWFL_1372.ECW_m1203,iY75_1357.Y75_RS05720,iZ_1308.Z1734,ic_1306.c1365 Ketoacyl-synt_C,ketoacyl-synt k141_19379_1 218284.CCDN010000005_gene3459 4.96e-68 217.0 COG1168@1|root,COG1168@2|Bacteria,1TP5G@1239|Firmicutes,4H9PE@91061|Bacilli,1ZCQC@1386|Bacillus 91061|Bacilli E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities patB - 4.4.1.8 ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 - R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 k141_26720_1 1294265.JCM21738_2109 4.16e-36 134.0 2ASSK@1|root,31I7S@2|Bacteria,1V7RU@1239|Firmicutes,4HJ2S@91061|Bacilli,1ZDBW@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_7480_1 935836.JAEL01000103_gene1860 2.35e-147 435.0 COG1164@1|root,COG1164@2|Bacteria,1TQ5W@1239|Firmicutes,4HAN9@91061|Bacilli,1ZCRR@1386|Bacillus 91061|Bacilli E COG1164 Oligoendopeptidase F pepF2 - - - - - - - - - - - Peptidase_M3,Peptidase_M3_N k141_17032_1 1042377.AFPJ01000002_gene516 2.45e-91 285.0 COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,1RPQD@1236|Gammaproteobacteria,469F1@72275|Alteromonadaceae 1236|Gammaproteobacteria E Creatinase/Prolidase N-terminal domain ampP - 3.4.11.9 ko:K01262 - - - - ko00000,ko01000,ko01002 - - - Creatinase_N,Creatinase_N_2,Peptidase_M24,Peptidase_M24_C k141_11104_1 926566.Terro_3685 3.8e-51 183.0 COG0086@1|root,COG0086@2|Bacteria,3Y2FZ@57723|Acidobacteria,2JIW0@204432|Acidobacteriia 204432|Acidobacteriia K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoC - 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 k141_12394_1 42565.FP66_13450 0.0 1025.0 COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,1RNBF@1236|Gammaproteobacteria,1XHJZ@135619|Oceanospirillales 135619|Oceanospirillales J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction pnp - 2.7.7.8 ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 M00394 R00437,R00438,R00439,R00440 RC02795 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 - - - KH_1,PNPase,RNase_PH,RNase_PH_C,S1 k141_18277_2 218284.CCDN010000002_gene2617 6.46e-56 179.0 COG1595@1|root,COG1595@2|Bacteria,1V9ZH@1239|Firmicutes,4HGNB@91061|Bacilli,1ZGEX@1386|Bacillus 91061|Bacilli K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_20539_1 218284.CCDN010000008_gene4192 7.64e-180 510.0 COG0624@1|root,COG0624@2|Bacteria,1TPEG@1239|Firmicutes,4HC14@91061|Bacilli,1ZBI2@1386|Bacillus 91061|Bacilli E Dipeptidase ytjP - 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20 k141_8761_1 218284.CCDN010000005_gene3200 3.73e-168 474.0 COG0095@1|root,COG0095@2|Bacteria,1TQ5U@1239|Firmicutes,4H9P6@91061|Bacilli,1ZBIZ@1386|Bacillus 91061|Bacilli H Lipoate-protein ligase lplJ GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0016874,GO:0016879,GO:0016979,GO:0017118,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:0140096,GO:1901564 6.3.1.20 ko:K03800 ko00785,ko01100,map00785,map01100 - R07770,R07771,R11143 RC00043,RC00070,RC00090,RC00992,RC02896 ko00000,ko00001,ko01000 - - - BPL_LplA_LipB,Lip_prot_lig_C k141_5138_3 218284.CCDN010000002_gene2848 6.79e-70 223.0 COG1486@1|root,COG1486@2|Bacteria,1TQ9I@1239|Firmicutes,4H9Z4@91061|Bacilli,1ZC6U@1386|Bacillus 91061|Bacilli G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases - - 3.2.1.86 ko:K01222 ko00010,ko00500,map00010,map00500 - R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 - GT4 - Glyco_hydro_4,Glyco_hydro_4C k141_25377_2 218284.CCDN010000005_gene3271 2.28e-148 423.0 COG1744@1|root,COG1744@2|Bacteria,1UY2H@1239|Firmicutes,4HCI5@91061|Bacilli,1ZBN4@1386|Bacillus 91061|Bacilli S Transcriptional activator protein med med - - ko:K05519,ko:K07335 - - - - ko00000,ko03000 - - - Bmp k141_6443_1 42565.FP66_07490 4.16e-36 122.0 2DTZA@1|root,33NAU@2|Bacteria,1QV5D@1224|Proteobacteria,1T294@1236|Gammaproteobacteria,1XMJH@135619|Oceanospirillales 135619|Oceanospirillales S Cell division protein ZapB zapB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K09892 - - - - ko00000,ko03036 - - - ZapB k141_6443_2 42565.FP66_07495 1.33e-26 100.0 COG0454@1|root,COG0456@2|Bacteria,1RIE6@1224|Proteobacteria,1S9G0@1236|Gammaproteobacteria,1XMBY@135619|Oceanospirillales 135619|Oceanospirillales K This enzyme acetylates the N-terminal alanine of ribosomal protein S18 rimI - 2.3.1.128 ko:K03789 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_1 k141_7481_1 312309.VF_A0350 1.44e-44 163.0 COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,1RPSJ@1236|Gammaproteobacteria,1XTPG@135623|Vibrionales 135623|Vibrionales T containing cAMP-binding and CBS domains - - - ko:K07182 - - - - ko00000 - - - CBS,DUF294,DUF294_C,cNMP_binding k141_26740_1 1453501.JELR01000002_gene502 8.18e-166 495.0 COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,1RSKR@1236|Gammaproteobacteria,46BA9@72275|Alteromonadaceae 1236|Gammaproteobacteria KLT Protein tyrosine kinase - - 2.7.11.1 ko:K08884,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - Pkinase,TPR_16,TPR_19,TPR_2,TPR_8 k141_26740_2 1279017.AQYJ01000028_gene2418 2.42e-169 479.0 COG1716@1|root,COG1716@2|Bacteria,1REM9@1224|Proteobacteria,1S46E@1236|Gammaproteobacteria 1236|Gammaproteobacteria T COG1716 FOG FHA domain - - - - - - - - - - - - FHA k141_26740_3 1042377.AFPJ01000048_gene2682 1.63e-101 303.0 COG1846@1|root,COG1846@2|Bacteria,1RF8X@1224|Proteobacteria,1S4RW@1236|Gammaproteobacteria,466UV@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG1846 Transcriptional regulators - - - - - - - - - - - - MarR k141_26740_4 1453501.JELR01000002_gene499 1.82e-88 265.0 COG0454@1|root,COG0456@2|Bacteria,1RHB7@1224|Proteobacteria,1S3TD@1236|Gammaproteobacteria,467KA@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases ectA GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016407,GO:0016740,GO:0016746,GO:0016747,GO:0018130,GO:0019491,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0042399,GO:0043170,GO:0043412,GO:0043436,GO:0043543,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.3.1.178 ko:K06718 ko00260,ko01100,ko01120,map00260,map01100,map01120 M00033 R06978 RC00004,RC00096 ko00000,ko00001,ko00002,ko01000 - - - Acetyltransf_1 k141_26740_5 1453501.JELR01000002_gene498 7.53e-286 785.0 COG0160@1|root,COG0160@2|Bacteria,1MWY6@1224|Proteobacteria,1RQKU@1236|Gammaproteobacteria,46611@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family ectB GO:0003674,GO:0003824,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0018130,GO:0019491,GO:0019752,GO:0032787,GO:0042399,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.6.1.76 ko:K00836 ko00260,ko01100,ko01120,ko01210,ko01230,map00260,map01100,map01120,map01210,map01230 M00033 R06977 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 k141_9942_1 754477.Q7C_93 1.09e-43 151.0 28KE4@1|root,2ZA0D@2|Bacteria,1MXZT@1224|Proteobacteria,1RYV4@1236|Gammaproteobacteria,4618K@72273|Thiotrichales 72273|Thiotrichales - - - - - - - - - - - - - - - k141_9942_2 754476.Q7A_1977 4.51e-34 127.0 COG0672@1|root,COG0672@2|Bacteria,1N48M@1224|Proteobacteria,1S7GF@1236|Gammaproteobacteria,4617H@72273|Thiotrichales 72273|Thiotrichales P )-iron permease - - - ko:K07243 - - - - ko00000,ko02000 2.A.108.1,2.A.108.2 - - FTR1 k141_14618_1 1453501.JELR01000001_gene1922 1.09e-34 126.0 COG3678@1|root,COG3678@2|Bacteria 2|Bacteria NPTU ATP-independent chaperone mediated protein folding - - - ko:K06006 - - - - ko00000,ko03110 - - - LTXXQ k141_14618_2 1279017.AQYJ01000026_gene358 4.09e-126 363.0 COG0745@1|root,COG0745@2|Bacteria,1MVCB@1224|Proteobacteria,1RMW7@1236|Gammaproteobacteria,466IP@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain cpxR - - ko:K07662 ko01503,ko02020,map01503,map02020 M00447,M00727,M00728 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C k141_14618_3 1279017.AQYJ01000026_gene359 1.77e-37 137.0 COG0642@1|root,COG2205@2|Bacteria,1N17V@1224|Proteobacteria,1T1JX@1236|Gammaproteobacteria,466X6@72275|Alteromonadaceae 1236|Gammaproteobacteria T Signal transduction histidine kinase cpxA - 2.7.13.3 ko:K07640 ko01503,ko02020,map01503,map02020 M00447,M00727,M00728 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA k141_5139_1 218284.CCDN010000002_gene2254 4.75e-99 302.0 COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TPJ8@1239|Firmicutes,4HA8X@91061|Bacilli,1ZC2B@1386|Bacillus 91061|Bacilli G IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar ptsG - 2.7.1.208 ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 M00265,M00266,M00268,M00270,M00272,M00303,M00806 R02738,R02780,R04111,R04394,R05132,R08559 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.1,4.A.1.1.11,4.A.1.1.12 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC k141_12396_1 1408303.JNJJ01000009_gene2249 2.39e-33 123.0 2ESB9@1|root,33JW0@2|Bacteria,1VMVV@1239|Firmicutes,4HSTZ@91061|Bacilli,1ZD8X@1386|Bacillus 91061|Bacilli - - yodN - - - - - - - - - - - - k141_13584_1 911008.GLAD_03775 5.81e-49 174.0 COG0699@1|root,COG0699@2|Bacteria,1QP4Q@1224|Proteobacteria,1SIRW@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Dynamin family - - - - - - - - - - - - Dynamin_N k141_4045_1 218284.CCDN010000004_gene3042 3.05e-136 398.0 COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,4HAB3@91061|Bacilli,1ZAPP@1386|Bacillus 91061|Bacilli JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity cshA GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 3.6.4.13 ko:K05592 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,Helicase_C k141_17033_1 1120999.JONM01000002_gene912 1.46e-39 137.0 COG1846@1|root,COG1846@2|Bacteria,1PC0C@1224|Proteobacteria,2VUH3@28216|Betaproteobacteria,2KRTS@206351|Neisseriales 206351|Neisseriales K helix_turn_helix multiple antibiotic resistance protein - - - - - - - - - - - - MarR k141_17033_2 742159.HMPREF0004_1672 1.78e-05 45.4 COG2259@1|root,COG2259@2|Bacteria,1N06A@1224|Proteobacteria,2VU8E@28216|Betaproteobacteria,3T7FN@506|Alcaligenaceae 28216|Betaproteobacteria S DoxX - - - ko:K15977 - - - - ko00000 - - - DoxX k141_15835_1 1219077.VAZ01S_130_00030 8.71e-74 221.0 2AN7V@1|root,31D5W@2|Bacteria,1RJ19@1224|Proteobacteria,1S5V8@1236|Gammaproteobacteria,1XXU3@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF2810) yibL - - ko:K14762 - - - - ko00000,ko03009 - - - DUF2810 k141_15835_2 223926.28808282 4.4e-222 614.0 COG1052@1|root,COG1052@2|Bacteria,1MVSS@1224|Proteobacteria,1RMWR@1236|Gammaproteobacteria,1XT4W@135623|Vibrionales 135623|Vibrionales C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family ldhA - 1.1.1.28 ko:K03778 ko00620,ko01120,map00620,map01120 - R00704 RC00044 ko00000,ko00001,ko01000 - - - 2-Hacid_dh,2-Hacid_dh_C k141_15835_3 1280001.BAOA01000053_gene2176 2.98e-96 282.0 COG3034@1|root,COG3034@2|Bacteria,1MXY6@1224|Proteobacteria,1S66I@1236|Gammaproteobacteria,1XXH1@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria - - - - - - - - - - - - YkuD k141_15835_4 1116375.VEJY3_16261 4.41e-138 394.0 COG0584@1|root,COG0584@2|Bacteria,1MU8H@1224|Proteobacteria,1RYTR@1236|Gammaproteobacteria,1XTUR@135623|Vibrionales 135623|Vibrionales C glycerophosphoryl diester phosphodiesterase - - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - GDPD k141_15835_5 1116375.VEJY3_16266 1.67e-203 566.0 COG0039@1|root,COG0039@2|Bacteria,1MV57@1224|Proteobacteria,1RPAX@1236|Gammaproteobacteria,1XWBX@135623|Vibrionales 135623|Vibrionales C Belongs to the LDH MDH superfamily - - 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 - R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 - - - Ldh_1_C,Ldh_1_N k141_15835_6 1116375.VEJY3_16286 1.87e-153 434.0 COG3883@1|root,COG3883@2|Bacteria,1MZ9M@1224|Proteobacteria,1T2AD@1236|Gammaproteobacteria,1XUWI@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF3450) - - - - - - - - - - - - DUF3450 k141_15835_7 1116375.VEJY3_16291 1.43e-262 727.0 COG0811@1|root,COG0811@2|Bacteria,1QNJ1@1224|Proteobacteria,1RQWT@1236|Gammaproteobacteria,1XSJP@135623|Vibrionales 135623|Vibrionales U COG0811 Biopolymer transport proteins - - - ko:K03561 - - - - ko00000,ko02000 1.A.30.2.1 - - MotA_ExbB k141_15835_8 1116375.VEJY3_16296 5.59e-120 343.0 COG0811@1|root,COG0811@2|Bacteria,1MX60@1224|Proteobacteria,1RRX1@1236|Gammaproteobacteria,1XT9X@135623|Vibrionales 135623|Vibrionales U TonB system transport protein exbB2 - - ko:K03561 - - - - ko00000,ko02000 1.A.30.2.1 - - MotA_ExbB k141_15835_9 316275.VSAL_II0902 6.2e-21 85.5 COG0848@1|root,COG0848@2|Bacteria,1RI4M@1224|Proteobacteria,1S7FH@1236|Gammaproteobacteria,1Y2NG@135623|Vibrionales 135623|Vibrionales U Biopolymer transport protein ExbD/TolR - - - ko:K03559 - - - - ko00000,ko02000 1.A.30.2.1 - - ExbD k141_2761_2 1279017.AQYJ01000021_gene2849 6.55e-34 117.0 COG3313@1|root,COG3313@2|Bacteria,1NGD5@1224|Proteobacteria,1SGHW@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Fe-S protein - - - ko:K06938 - - - - ko00000 - - - DUF1289 k141_2761_3 1123060.JONP01000010_gene2344 4.62e-21 88.6 COG0663@1|root,COG0663@2|Bacteria,1RD76@1224|Proteobacteria,2U5GR@28211|Alphaproteobacteria,2JSV3@204441|Rhodospirillales 204441|Rhodospirillales S Bacterial transferase hexapeptide (six repeats) - - - - - - - - - - - - Hexapep k141_13585_1 1294265.JCM21738_2264 1.55e-84 252.0 COG0220@1|root,COG0220@2|Bacteria,1TQCA@1239|Firmicutes,4HC08@91061|Bacilli,1ZAP2@1386|Bacillus 91061|Bacilli J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA trmB GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 ko:K03439 - - - - ko00000,ko01000,ko03016 - - - Methyltransf_4 k141_23048_2 1279017.AQYJ01000029_gene3312 9.16e-28 102.0 COG3630@1|root,COG3630@2|Bacteria,1NERX@1224|Proteobacteria,1SD6N@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Oxaloacetate decarboxylase, gamma chain - - - - - - - - - - - - OAD_gamma k141_23048_4 1283300.ATXB01000001_gene1705 3.54e-266 746.0 COG1387@1|root,COG1387@2|Bacteria,1MYXV@1224|Proteobacteria,1SZW9@1236|Gammaproteobacteria,1XFPE@135618|Methylococcales 135618|Methylococcales L DNA polymerase X family - - - ko:K02347 - - - - ko00000,ko03400 - - - DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8,PHP k141_20540_2 1042377.AFPJ01000007_gene1879 1.02e-130 393.0 COG0417@1|root,COG0417@2|Bacteria,1MVY9@1224|Proteobacteria,1RMQ1@1236|Gammaproteobacteria,4640I@72275|Alteromonadaceae 1236|Gammaproteobacteria L DNA polymerase polB GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0018130,GO:0019438,GO:0031668,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0045004,GO:0045005,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02336 - - - - ko00000,ko01000,ko03400 - - - DNA_pol_B,DNA_pol_B_exo1 k141_25378_1 1453501.JELR01000001_gene3149 8.96e-85 263.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,465Q7@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - - - - - - - - - - HTH_8,Response_reg,Sigma54_activat k141_25378_2 1453501.JELR01000001_gene3148 9.92e-43 150.0 COG0577@1|root,COG0577@2|Bacteria,1MXFC@1224|Proteobacteria,1RQX0@1236|Gammaproteobacteria,46698@72275|Alteromonadaceae 1236|Gammaproteobacteria V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD k141_35968_1 42565.FP66_07920 3.68e-63 212.0 COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,1RMQE@1236|Gammaproteobacteria,1XH6K@135619|Oceanospirillales 135619|Oceanospirillales J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs rnr - - ko:K12573 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03016,ko03019 - - - HTH_12,OB_RNB,RNB,S1 k141_499_2 1453501.JELR01000001_gene2617 1.56e-112 330.0 COG0491@1|root,COG0491@2|Bacteria,1MU8Q@1224|Proteobacteria,1S22I@1236|Gammaproteobacteria,466DR@72275|Alteromonadaceae 1236|Gammaproteobacteria S Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid gloB GO:0003674,GO:0003824,GO:0004416,GO:0006518,GO:0006575,GO:0006749,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0034641,GO:0043603,GO:0044237,GO:0051186,GO:0071704,GO:1901564 3.1.2.6 ko:K01069 ko00620,map00620 - R01736 RC00004,RC00137 ko00000,ko00001,ko01000 - - - HAGH_C,Lactamase_B k141_499_3 1453501.JELR01000001_gene2618 8.9e-136 400.0 COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,1RMFZ@1236|Gammaproteobacteria,464A9@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) mltD GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008932,GO:0008933,GO:0009893,GO:0016020,GO:0016740,GO:0016757,GO:0019222,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043085,GO:0044093,GO:0044464,GO:0048518,GO:0050789,GO:0050790,GO:0051341,GO:0051353,GO:0061783,GO:0065007,GO:0065009 - ko:K08307 - - - - ko00000,ko01000,ko01011 - - - LysM,SLT k141_5140_1 218284.CCDN010000006_gene3653 7.29e-90 274.0 COG3595@1|root,COG3595@2|Bacteria,1TS90@1239|Firmicutes,4HDI6@91061|Bacilli,1ZC95@1386|Bacillus 91061|Bacilli S Putative adhesin yvlB - - - - - - - - - - - DUF4097 k141_8763_1 218284.CCDN010000005_gene3268 1.77e-142 429.0 COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HACY@91061|Bacilli,1ZB8K@1386|Bacillus 91061|Bacilli O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE clpB GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564 - ko:K03695 ko04213,map04213 - - - ko00000,ko00001,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N k141_34834_1 223926.28810126 1.06e-294 809.0 COG0591@1|root,COG0591@2|Bacteria,1MUBI@1224|Proteobacteria,1RMXU@1236|Gammaproteobacteria,1XSU8@135623|Vibrionales 135623|Vibrionales E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family putP - - ko:K11928 - - - - ko00000,ko02000 2.A.21.2 - - SSF k141_34834_2 223926.28810127 4.25e-156 439.0 COG4230@1|root,COG4230@2|Bacteria,1MYWH@1224|Proteobacteria,1S86Z@1236|Gammaproteobacteria,1XSMU@135623|Vibrionales 135623|Vibrionales C COG4230 Delta 1-pyrroline-5-carboxylate dehydrogenase - - - - - - - - - - - - Aldedh k141_34834_3 674977.VMC_06150 2.37e-161 481.0 COG0506@1|root,COG4230@1|root,COG0506@2|Bacteria,COG4230@2|Bacteria,1MV93@1224|Proteobacteria,1RN48@1236|Gammaproteobacteria,1XTWM@135623|Vibrionales 135623|Vibrionales C Oxidizes proline to glutamate for use as a carbon and nitrogen source putA - 1.2.1.88,1.5.5.2 ko:K13821 ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130 - R00245,R00707,R00708,R01253,R04444,R04445,R05051 RC00080,RC00083,RC00216,RC00242,RC00255 ko00000,ko00001,ko01000,ko03000 - - - Aldedh,Pro_dh,Pro_dh-DNA_bdg k141_7482_1 1244869.H261_07738 8.97e-36 129.0 COG0279@1|root,COG0279@2|Bacteria,1NVIE@1224|Proteobacteria,2U8QT@28211|Alphaproteobacteria,2JSGE@204441|Rhodospirillales 204441|Rhodospirillales G Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate gmhA - 5.3.1.28 ko:K03271 ko00540,ko01100,map00540,map01100 M00064 R05645,R09768,R09769 RC00434 ko00000,ko00001,ko00002,ko01000,ko01005 - - - SIS_2 k141_23049_2 796606.BMMGA3_00135 5.07e-18 77.4 2EHEM@1|root,33B6J@2|Bacteria,1VM3Z@1239|Firmicutes,4HR3I@91061|Bacilli,1ZIUR@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2508) yaaL - - - - - - - - - - - DUF2508 k141_34835_2 218284.CCDN010000001_gene96 5.6e-67 211.0 COG1893@1|root,COG1893@2|Bacteria,1V1NJ@1239|Firmicutes,4HFWT@91061|Bacilli,1ZFJY@1386|Bacillus 91061|Bacilli H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid panE GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008677,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU15110 ApbA,ApbA_C k141_2762_1 1453501.JELR01000002_gene991 7.36e-40 143.0 COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,1RQDA@1236|Gammaproteobacteria,4666A@72275|Alteromonadaceae 1236|Gammaproteobacteria T signal transduction protein with a C-terminal ATPase domain algZ - 2.7.13.3 ko:K08082 ko02020,map02020 M00493 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - His_kinase k141_27609_1 223926.28807702 3.29e-158 515.0 COG5571@1|root,COG5571@2|Bacteria,1RE9R@1224|Proteobacteria,1S5NY@1236|Gammaproteobacteria,1XUFR@135623|Vibrionales 135623|Vibrionales N alginic acid biosynthetic process - - - ko:K12287 - - - - ko00000,ko02044 - - - - k141_27609_2 1280001.BAOA01000048_gene1835 5.51e-240 660.0 COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,1RN82@1236|Gammaproteobacteria,1XSBK@135623|Vibrionales 135623|Vibrionales D Rod shape-determining protein MreB mreB - - ko:K03569 - - - - ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 - - MreB_Mbl k141_27609_3 1116375.VEJY3_13790 7.56e-191 532.0 COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,1RMK4@1236|Gammaproteobacteria,1XSEQ@135623|Vibrionales 135623|Vibrionales M Involved in formation and maintenance of cell shape mreC - - ko:K03570 - - - - ko00000,ko03036 9.B.157.1 - - MreC k141_27609_4 1116375.VEJY3_13785 5.82e-109 314.0 COG2891@1|root,COG2891@2|Bacteria,1RER7@1224|Proteobacteria,1S4DE@1236|Gammaproteobacteria,1XTT8@135623|Vibrionales 135623|Vibrionales M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins mreD - - ko:K03571 - - - - ko00000,ko03036 9.B.157.1 - - MreD k141_27609_5 223926.28807698 4.04e-120 344.0 COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,1S41D@1236|Gammaproteobacteria,1XVZI@135623|Vibrionales 135623|Vibrionales D COG0424 Nucleotide-binding protein implicated in inhibition of septum formation maf - - ko:K06287 - - - - ko00000 - - - Maf k141_27609_6 223926.28807697 0.0 925.0 COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,1RMIW@1236|Gammaproteobacteria,1XTMA@135623|Vibrionales 135623|Vibrionales J COG1530 Ribonucleases G and E rng - - ko:K08301 - - - - ko00000,ko01000,ko03009,ko03019 - - - RNase_E_G,S1 k141_27609_7 1116375.VEJY3_13770 0.0 1320.0 COG3164@1|root,COG3164@2|Bacteria,1MXWF@1224|Proteobacteria,1RNUK@1236|Gammaproteobacteria,1XTHT@135623|Vibrionales 135623|Vibrionales S Protein of unknown function VV2929 - - - - - - - - - - - AsmA_2,DUF3971 k141_5141_1 218284.CCDN010000001_gene192 8.6e-160 453.0 COG0784@1|root,COG0835@1|root,COG0784@2|Bacteria,COG0835@2|Bacteria,1TRJU@1239|Firmicutes,4HCPT@91061|Bacilli,1ZAYA@1386|Bacillus 91061|Bacilli T Chemotaxis protein CheV cheV GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0044424,GO:0044444,GO:0044464,GO:0050896 - ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - CheW,Response_reg k141_23050_1 1294265.JCM21738_1208 2.11e-54 179.0 COG3508@1|root,COG3508@2|Bacteria,1UYZ0@1239|Firmicutes,4HCCC@91061|Bacilli,1ZC6Q@1386|Bacillus 91061|Bacilli Q homogentisate 12-dioxygenase hmgA - 1.13.11.5 ko:K00451 ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120 M00044 R02519 RC00737 ko00000,ko00001,ko00002,ko01000 - - - HgmA k141_23050_2 1294265.JCM21738_1209 3.25e-56 182.0 COG0179@1|root,COG0179@2|Bacteria,1UY98@1239|Firmicutes,4HC89@91061|Bacilli,1ZCD1@1386|Bacillus 91061|Bacilli Q Fumarylacetoacetate (FAA) hydrolase family - - 3.7.1.2 ko:K16171 ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120 M00044 R01364 RC00326,RC00446 ko00000,ko00001,ko00002,ko01000 - - - FAA_hydrolase k141_4046_1 675814.VIC_001110 1.15e-114 355.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RSD8@1236|Gammaproteobacteria 1236|Gammaproteobacteria NT methyl-accepting chemotaxis protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - MCPsignal k141_35092_1 1121285.AUFK01000006_gene1940 9.12e-05 42.4 2A51Y@1|root,30TQ9@2|Bacteria,4PHEW@976|Bacteroidetes,1IM3G@117743|Flavobacteriia,3ZU37@59732|Chryseobacterium 976|Bacteroidetes - - - - - - - - - - - - - - - k141_29064_1 598659.NAMH_0355 3.01e-26 112.0 COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,42P35@68525|delta/epsilon subdivisions,2YN2K@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria M Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxB - 2.4.1.182 ko:K00748 ko00540,ko01100,map00540,map01100 M00060 R04606 RC00005,RC00059 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT19 iIT341.HP0867 LpxB k141_11395_1 218284.CCDN010000005_gene3350 9.54e-100 297.0 COG2200@1|root,COG2200@2|Bacteria,1TQ94@1239|Firmicutes,4HAK1@91061|Bacilli,1ZPXF@1386|Bacillus 91061|Bacilli T Putative diguanylate phosphodiesterase M1-600 - - - - - - - - - - - EAL k141_1683_2 1306406.ASHX01000002_gene5071 0.000201 48.1 COG0457@1|root,COG3903@1|root,COG0457@2|Bacteria,COG3903@2|Bacteria,2I7Q6@201174|Actinobacteria 201174|Actinobacteria K stress, protein - - - - - - - - - - - - NaeI k141_2894_1 1515746.HR45_09470 9.31e-20 83.6 COG2827@1|root,COG2827@2|Bacteria,1N6PA@1224|Proteobacteria,1SCBH@1236|Gammaproteobacteria,2QCJG@267890|Shewanellaceae 1236|Gammaproteobacteria L PFAM Excinuclease ABC, C subunit domain protein yhbQ GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - ko:K07461 - - - - ko00000 - - - GIY-YIG k141_21964_1 935836.JAEL01000026_gene4988 1.57e-20 89.4 COG4585@1|root,COG4585@2|Bacteria,1TPDG@1239|Firmicutes,4HC7E@91061|Bacilli,1ZB48@1386|Bacillus 91061|Bacilli T Histidine kinase - - 2.7.13.3 ko:K11617 ko02020,map02020 M00481,M00754 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA_3 k141_21964_2 1034347.CAHJ01000017_gene3463 6.6e-110 320.0 COG2197@1|root,COG2197@2|Bacteria,1TQ1U@1239|Firmicutes,4HE6R@91061|Bacilli,1ZD6A@1386|Bacillus 91061|Bacilli T Bacterial regulatory proteins, luxR family - - - ko:K11618 ko02020,map02020 M00481,M00754 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg k141_25659_1 218284.CCDN010000004_gene3094 1.8e-95 280.0 COG0431@1|root,COG0431@2|Bacteria,1V3WV@1239|Firmicutes,4HHT9@91061|Bacilli,1ZGEI@1386|Bacillus 91061|Bacilli S NADPH-dependent FMN reductase azr - 1.7.1.6 ko:K03206 - - - - ko00000,ko01000 - - - FMN_red k141_5440_1 1453501.JELR01000001_gene3100 2.13e-64 205.0 COG0454@1|root,COG3011@1|root,COG0456@2|Bacteria,COG3011@2|Bacteria,1QUWI@1224|Proteobacteria,1T23R@1236|Gammaproteobacteria,468WI@72275|Alteromonadaceae 1236|Gammaproteobacteria K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1 k141_5440_2 236097.ADG881_89 1.71e-23 94.0 2BUA7@1|root,338MP@2|Bacteria,1NCMA@1224|Proteobacteria,1SE2B@1236|Gammaproteobacteria,1XMU2@135619|Oceanospirillales 135619|Oceanospirillales S DoxX-like family - - - - - - - - - - - - DoxX_3 k141_30148_1 1132442.KB889752_gene265 4.59e-34 131.0 2D8E6@1|root,32TR4@2|Bacteria,1VAUI@1239|Firmicutes,4HME1@91061|Bacilli,1ZC3S@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_30148_2 1444306.JFZC01000034_gene2636 1.01e-71 231.0 2E4XD@1|root,32ZR9@2|Bacteria,1VFZU@1239|Firmicutes,4HPWW@91061|Bacilli 91061|Bacilli S Phage minor capsid protein 2 - - - - - - - - - - - - Phage_Mu_F,Phage_min_cap2 k141_30148_5 1444310.JANV01000162_gene1173 6.82e-107 322.0 2DB75@1|root,2Z7JY@2|Bacteria,1TSI8@1239|Firmicutes,4IRVK@91061|Bacilli,1ZJU4@1386|Bacillus 91061|Bacilli S Phage major capsid protein E - - - - - - - - - - - - Phage_cap_E k141_30148_7 1444310.JANV01000162_gene1171 2e-20 86.7 2DIUB@1|root,3044U@2|Bacteria,1TW14@1239|Firmicutes,4I4QF@91061|Bacilli,1ZPFJ@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_30148_8 698769.JFBD01000002_gene2739 5.72e-08 54.3 2FH19@1|root,348W5@2|Bacteria,1VZUQ@1239|Firmicutes,4HZ5J@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - k141_30148_9 1444306.JFZC01000034_gene2629 4.63e-58 185.0 2ER1M@1|root,33IM5@2|Bacteria,1VQRC@1239|Firmicutes,4HSFK@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - HK97-gp10_like k141_30148_12 66692.ABC2827 8.07e-23 95.9 29T45@1|root,30EAU@2|Bacteria,1UCBS@1239|Firmicutes,4INU7@91061|Bacilli,1ZNYF@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_30148_14 1444309.JAQG01000145_gene2684 1.48e-59 227.0 COG5280@1|root,COG5412@1|root,COG5280@2|Bacteria,COG5412@2|Bacteria,1TQ28@1239|Firmicutes,4HGP4@91061|Bacilli,26UKE@186822|Paenibacillaceae 91061|Bacilli E minor tail protein - - - - - - - - - - - - PhageMin_Tail k141_14770_1 218284.CCDN010000005_gene3466 3.9e-74 223.0 COG1098@1|root,COG1098@2|Bacteria,1VASQ@1239|Firmicutes,4HKSW@91061|Bacilli,1ZHK5@1386|Bacillus 91061|Bacilli J RNA binding protein (contains ribosomal protein S1 domain) yugI - - ko:K07570,ko:K07571 - - - - ko00000 - - - S1 k141_14770_2 218284.CCDN010000005_gene3467 3.12e-71 221.0 28K3D@1|root,2Z9SI@2|Bacteria,1UZKH@1239|Firmicutes,4HDH6@91061|Bacilli,1ZI4E@1386|Bacillus 91061|Bacilli S MEDS: MEthanogen/methylotroph, DcmR Sensory domain - - - - - - - - - - - - MEDS k141_14770_3 218284.CCDN010000005_gene3468 9.4e-199 560.0 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli,1ZAY9@1386|Bacillus 91061|Bacilli C Belongs to the aldehyde dehydrogenase family acoD - - ko:K00138 ko00010,ko00620,ko01100,ko01110,ko01120,map00010,map00620,map01100,map01110,map01120 - R00711 RC00047 ko00000,ko00001,ko01000 - - - Aldedh k141_12649_2 1279017.AQYJ01000029_gene3803 9.73e-49 162.0 COG1806@1|root,COG1806@2|Bacteria,1MUHU@1224|Proteobacteria,1RPHX@1236|Gammaproteobacteria,465QN@72275|Alteromonadaceae 1236|Gammaproteobacteria S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation ydiA GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0030234,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0065007,GO:0065009,GO:0098772 2.7.11.33,2.7.4.28 ko:K09773 - - - - ko00000,ko01000 - - - Kinase-PPPase k141_6560_1 1117647.M5M_10265 8.19e-89 288.0 COG3866@1|root,COG4733@1|root,COG3866@2|Bacteria,COG4733@2|Bacteria,1RGJR@1224|Proteobacteria,1S4RB@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Pectate lyase - - - - - - - - - - - - fn3 k141_6560_2 1117647.M5M_10280 4.76e-51 177.0 COG3866@1|root,COG3866@2|Bacteria,1QPFF@1224|Proteobacteria,1RY07@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Pectate lyase pelB - 4.2.2.2 ko:K01728 ko00040,ko02024,map00040,map02024 - R02361,R06240 RC00049,RC00705 ko00000,ko00001,ko01000 - - - Pec_lyase_C,Pectinesterase k141_5441_1 1120947.ATUX01000007_gene879 1.69e-40 149.0 COG0008@1|root,COG0008@2|Bacteria,2GJJS@201174|Actinobacteria,4D333@85005|Actinomycetales 201174|Actinobacteria J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) gltX GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 6.1.1.17 ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 - - iNJ661.Rv2992c tRNA-synt_1c k141_5441_2 749927.AMED_1698 7.17e-15 72.8 COG0179@1|root,COG0179@2|Bacteria,2GN2G@201174|Actinobacteria,4E0EH@85010|Pseudonocardiales 201174|Actinobacteria Q 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase odx - - - - - - - - - - - DUF2437,FAA_hydrolase k141_721_1 218284.CCDN010000001_gene681 2.38e-93 273.0 COG1959@1|root,COG1959@2|Bacteria,1V3QB@1239|Firmicutes,4HHCF@91061|Bacilli,1ZFKT@1386|Bacillus 91061|Bacilli K Transcriptional regulator cymR GO:0001047,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0005575,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0032991,GO:0032993,GO:0042802,GO:0042803,GO:0043933,GO:0044085,GO:0044212,GO:0046983,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051291,GO:0065003,GO:0071840,GO:0097159,GO:1901363 - ko:K17472 - - - - ko00000,ko03000 - - - Rrf2 k141_2895_1 1279017.AQYJ01000027_gene1667 3.26e-98 297.0 COG2223@1|root,COG2223@2|Bacteria,1MU27@1224|Proteobacteria,1RMUK@1236|Gammaproteobacteria,4652C@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG2223 Nitrate nitrite transporter narK1 - - ko:K02575 ko00910,map00910 M00615 - - ko00000,ko00001,ko00002,ko02000 2.A.1.8 - - MFS_1 k141_24322_1 218284.CCDN010000001_gene224 1.16e-65 206.0 2E5MF@1|root,330CC@2|Bacteria,1VEG0@1239|Firmicutes,4HMVE@91061|Bacilli,1ZBQY@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2953) ytfI - - - - - - - - - - - DUF2953 k141_13837_1 218284.CCDN010000008_gene4207 1.95e-05 46.2 COG3104@1|root,COG3104@2|Bacteria,1TP81@1239|Firmicutes,4HAF2@91061|Bacilli,1ZAVZ@1386|Bacillus 91061|Bacilli E amino acid peptide transporter dtpT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03305 - - - - ko00000 2.A.17 - - PTR2 k141_13837_2 218284.CCDN010000008_gene4207 1.02e-170 489.0 COG3104@1|root,COG3104@2|Bacteria,1TP81@1239|Firmicutes,4HAF2@91061|Bacilli,1ZAVZ@1386|Bacillus 91061|Bacilli E amino acid peptide transporter dtpT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03305 - - - - ko00000 2.A.17 - - PTR2 k141_20735_1 1279017.AQYJ01000027_gene1591 2.24e-39 150.0 COG0643@1|root,COG0784@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,4650G@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0643 Chemotaxis protein histidine kinase and related kinases chpA - - ko:K02487,ko:K06596 ko02020,ko02025,map02020,map02025 M00507 - - ko00000,ko00001,ko00002,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg k141_11397_1 1385511.N783_21540 3.95e-22 90.9 COG0801@1|root,COG0801@2|Bacteria,1V6PR@1239|Firmicutes,4HIMG@91061|Bacilli,2YAF1@289201|Pontibacillus 91061|Bacilli H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase folK - 2.7.6.3 ko:K00950 ko00790,ko01100,map00790,map01100 M00126,M00841 R03503 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - HPPK k141_11397_2 558169.AGAV01000015_gene257 5.43e-40 135.0 COG1539@1|root,COG1539@2|Bacteria,1VA0I@1239|Firmicutes,4HKKK@91061|Bacilli 91061|Bacilli H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin folB - 1.13.11.81,4.1.2.25,5.1.99.8 ko:K01633 ko00790,ko01100,map00790,map01100 M00126,M00840 R03504,R11037,R11073 RC00721,RC00943,RC01479,RC03333,RC03334 ko00000,ko00001,ko00002,ko01000 - - - FolB k141_10227_1 1116375.VEJY3_14565 2.11e-294 816.0 COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,1RPF7@1236|Gammaproteobacteria,1XTUK@135623|Vibrionales 135623|Vibrionales CO Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps dsbD GO:0003674,GO:0003756,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008152,GO:0009987,GO:0015035,GO:0015036,GO:0016020,GO:0016021,GO:0016043,GO:0016491,GO:0016667,GO:0016853,GO:0016860,GO:0016864,GO:0017004,GO:0019725,GO:0022607,GO:0031224,GO:0031226,GO:0034622,GO:0042592,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0055114,GO:0065003,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0140096 1.8.1.8 ko:K04084 - - - - ko00000,ko01000,ko03110 5.A.1.1 - - DsbC,DsbD,Thioredoxin_7 k141_10227_2 1219076.N646_1952 1.12e-133 389.0 COG2704@1|root,COG2704@2|Bacteria,1MVHH@1224|Proteobacteria,1RPTE@1236|Gammaproteobacteria,1XT7X@135623|Vibrionales 135623|Vibrionales S Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane dcuA - - ko:K07791 - - - - ko00000,ko02000 2.A.13.1 - - DcuA_DcuB k141_5442_1 218284.CCDN010000007_gene3950 1.4e-144 421.0 COG0018@1|root,COG0018@2|Bacteria,1TPEZ@1239|Firmicutes,4HAR3@91061|Bacilli,1ZBP1@1386|Bacillus 91061|Bacilli J Arginyl-tRNA synthetase argS GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d k141_26993_2 268407.PWYN_08655 5.62e-32 113.0 2EFV8@1|root,335FH@2|Bacteria,1VHPC@1239|Firmicutes,4HNKU@91061|Bacilli,276ZP@186822|Paenibacillaceae 91061|Bacilli S Protein of unknown function (DUF2642) - - - - - - - - - - - - DUF2642 k141_2912_1 521098.Aaci_1275 1.73e-11 67.8 COG0771@1|root,COG0771@2|Bacteria,1TQ3P@1239|Firmicutes,4HA5P@91061|Bacilli,2785Y@186823|Alicyclobacillaceae 91061|Bacilli M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) murD - 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase_C,Mur_ligase_M k141_2912_2 665571.STHERM_c08950 7.2e-77 241.0 COG0472@1|root,COG0472@2|Bacteria,2J6QK@203691|Spirochaetes 203691|Spirochaetes M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan mraY - 2.7.8.13 ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 - R05629,R05630 RC00002,RC02753 ko00000,ko00001,ko01000,ko01011 9.B.146 - - Glycos_transf_4,MraY_sig1 k141_36144_1 218284.CCDN010000002_gene2123 1.24e-116 345.0 COG0065@1|root,COG0065@2|Bacteria,1TPE5@1239|Firmicutes,4HAWA@91061|Bacilli,1ZCF1@1386|Bacillus 91061|Bacilli E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate leuC - 4.2.1.33,4.2.1.35 ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170 RC00497,RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS10700 Aconitase k141_11425_2 1121090.KB894685_gene3997 5.74e-11 63.2 29N4B@1|root,30923@2|Bacteria,1U4B4@1239|Firmicutes,4IE2Q@91061|Bacilli,1ZNHV@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_6588_1 1034347.CAHJ01000038_gene4197 2.26e-93 281.0 COG0334@1|root,COG0334@2|Bacteria,1TQU2@1239|Firmicutes,4HAB2@91061|Bacilli,1ZB55@1386|Bacillus 91061|Bacilli E Belongs to the Glu Leu Phe Val dehydrogenases family ldh - 1.4.1.9 ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 - R01088,R01434,R02196 RC00006,RC00036 ko00000,ko00001,ko01000 - - - ELFV_dehydrog,ELFV_dehydrog_N k141_5461_1 768671.ThimaDRAFT_2338 0.00013 51.6 COG0543@1|root,COG0633@1|root,COG0543@2|Bacteria,COG0633@2|Bacteria,1MV72@1224|Proteobacteria,1RPH5@1236|Gammaproteobacteria,1WXHI@135613|Chromatiales 135613|Chromatiales C Oxidoreductase FAD-binding domain - - 1.17.1.1 ko:K00523 ko00520,map00520 - R03391,R03392 RC00230 ko00000,ko00001,ko01000 - - - FAD_binding_6,Fer2,NAD_binding_1 k141_5461_2 218284.CCDN010000002_gene2870 8.84e-106 321.0 COG3290@1|root,COG3290@2|Bacteria,1TQJR@1239|Firmicutes,4H9Q0@91061|Bacilli,1ZBHV@1386|Bacillus 91061|Bacilli T Signal transduction histidine kinase regulating citrate malate metabolism citS - 2.7.13.3 ko:K11637 ko02020,map02020 M00487 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,PAS,PAS_8,PAS_9,SPOB_a,sCache_3_2 k141_18537_2 1453501.JELR01000002_gene1471 7.23e-43 151.0 COG0845@1|root,COG0845@2|Bacteria,1PEVY@1224|Proteobacteria,1RPEQ@1236|Gammaproteobacteria,465PN@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - - - - - - - - - - Biotin_lipoyl_2,HlyD_3 k141_32548_1 1294265.JCM21738_3728 2.21e-69 212.0 COG0094@1|root,COG0094@2|Bacteria,1TPE0@1239|Firmicutes,4HBAX@91061|Bacilli,1ZB6T@1386|Bacillus 91061|Bacilli J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits rplE GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02931 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L5,Ribosomal_L5_C k141_32548_7 935836.JAEL01000067_gene1670 1.05e-143 406.0 COG0092@1|root,COG0092@2|Bacteria,1TPCP@1239|Firmicutes,4HAUR@91061|Bacilli,1ZBA9@1386|Bacillus 91061|Bacilli J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation rpsC GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02982 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KH_2,Ribosomal_S3_C k141_4201_1 408672.NBCG_04195 6.14e-13 68.9 COG1231@1|root,COG1231@2|Bacteria,2GK23@201174|Actinobacteria,4DP12@85009|Propionibacteriales 201174|Actinobacteria E amine oxidase aofH GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.4.3.4 ko:K00274 ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034 M00135 R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354 RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713 ko00000,ko00001,ko00002,ko01000 - - - Amino_oxidase k141_26994_1 218284.CCDN010000007_gene3937 1.45e-109 322.0 COG0095@1|root,COG0095@2|Bacteria,1TQKA@1239|Firmicutes,4HCPS@91061|Bacilli,1ZCIA@1386|Bacillus 91061|Bacilli H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes lipL GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.3.1.200,2.3.1.204 ko:K16869,ko:K18821 - - - - ko00000,ko01000 - - - BPL_LplA_LipB k141_7654_1 553385.JEMF01000021_gene3052 6.83e-12 64.7 COG0609@1|root,COG0609@2|Bacteria,1MV9W@1224|Proteobacteria,1RMDF@1236|Gammaproteobacteria,1XRBZ@135619|Oceanospirillales 135619|Oceanospirillales P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily - - - ko:K02015 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - FecCD k141_7654_2 42565.FP66_11355 1.28e-76 238.0 COG4779@1|root,COG4779@2|Bacteria,1R57I@1224|Proteobacteria,1RRUA@1236|Gammaproteobacteria,1XKAJ@135619|Oceanospirillales 135619|Oceanospirillales P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily - - - ko:K02015 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - FecCD k141_30167_1 1294265.JCM21738_1791 1.66e-67 205.0 2E4BW@1|root,32Z7G@2|Bacteria,1VH0F@1239|Firmicutes,4HPQD@91061|Bacilli,1ZJ7Q@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2512) ycbP - - - - - - - - - - - DUF2512 k141_30167_2 1294265.JCM21738_1792 1.99e-34 119.0 COG2120@1|root,COG2120@2|Bacteria,1VA8Q@1239|Firmicutes,4HKMK@91061|Bacilli,1ZH30@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF1806) yojF - - - - - - - - - - - DUF1806 k141_14795_1 1453501.JELR01000002_gene784 2.61e-148 428.0 COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,1RMWU@1236|Gammaproteobacteria,4658B@72275|Alteromonadaceae 1236|Gammaproteobacteria M Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation surA GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006457,GO:0006458,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0022607,GO:0030288,GO:0030313,GO:0031647,GO:0031975,GO:0033218,GO:0036211,GO:0042277,GO:0042597,GO:0043163,GO:0043165,GO:0043170,GO:0043412,GO:0044085,GO:0044091,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0044764,GO:0045229,GO:0050821,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0060274,GO:0061024,GO:0061077,GO:0065007,GO:0065008,GO:0071704,GO:0071709,GO:0071840,GO:0140096,GO:1901564 5.2.1.8 ko:K03771 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_3,SurA_N k141_5462_1 1279017.AQYJ01000028_gene2086 1.87e-111 329.0 COG2831@1|root,COG2831@2|Bacteria,1QW38@1224|Proteobacteria,1T2R4@1236|Gammaproteobacteria,464F6@72275|Alteromonadaceae 1236|Gammaproteobacteria U Protein of unknown function (DUF3570) - - - - - - - - - - - - DUF3570 k141_16043_1 1294265.JCM21738_34 7.23e-50 171.0 COG0697@1|root,COG0697@2|Bacteria,1TP7K@1239|Firmicutes,4HBWN@91061|Bacilli,1ZB54@1386|Bacillus 91061|Bacilli EG Stage V sporulation protein AF spoVAF - - ko:K06408 - - - - ko00000 - - - GerA k141_27773_2 1453501.JELR01000002_gene945 1.2e-34 131.0 COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,1RN3Z@1236|Gammaproteobacteria,465HK@72275|Alteromonadaceae 1236|Gammaproteobacteria U COG4796 Type II secretory pathway, component HofQ pilQ GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0015976,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 - ko:K02507,ko:K02666 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - AMIN,STN,Secretin,Secretin_N k141_11426_1 218284.CCDN010000001_gene1489 6.14e-164 481.0 COG0188@1|root,COG0188@2|Bacteria,1TRE7@1239|Firmicutes,4HAQB@91061|Bacilli,1ZBCI@1386|Bacillus 91061|Bacilli L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K02621 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseA_C,DNA_topoisoIV k141_21992_1 1224318.DT73_01210 8.44e-169 480.0 COG1064@1|root,COG1064@2|Bacteria,1MUTT@1224|Proteobacteria,1S0KW@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Molecular chaperone GroES - - - - - - - - - - - - ADH_N,ADH_zinc_N k141_6590_1 218284.CCDN010000002_gene2069 2.9e-71 219.0 COG2364@1|root,COG2364@2|Bacteria,1V3NC@1239|Firmicutes,4HGRQ@91061|Bacilli,1ZCBH@1386|Bacillus 91061|Bacilli S Membrane - - - ko:K07149 - - - - ko00000 - - - - k141_19664_1 1128421.JAGA01000001_gene2328 0.000683 46.2 COG1595@1|root,COG1595@2|Bacteria,2NR5Q@2323|unclassified Bacteria 2|Bacteria K RNA polymerase sigma factor - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_2913_1 666686.B1NLA3E_04175 2.71e-70 239.0 COG2909@1|root,COG3629@1|root,COG2909@2|Bacteria,COG3629@2|Bacteria,1UWHI@1239|Firmicutes,4HADH@91061|Bacilli,1ZE89@1386|Bacillus 91061|Bacilli KT COG2909 ATP-dependent transcriptional regulator - - - ko:K03556 - - - - ko00000,ko03000 - - - AAA_16,BTAD,TPR_12,TPR_8 k141_13866_3 1500281.JQKZ01000001_gene1242 1.71e-47 167.0 COG3409@1|root,COG3409@2|Bacteria,4NFKN@976|Bacteroidetes,1HWSX@117743|Flavobacteriia,3ZRFD@59732|Chryseobacterium 976|Bacteroidetes M N-acetylmuramidase - - - - - - - - - - - - Muraidase,PG_binding_1 k141_26995_1 1121013.P873_08670 3.86e-22 95.1 COG3453@1|root,COG3453@2|Bacteria,1N0WC@1224|Proteobacteria,1S8TP@1236|Gammaproteobacteria,1X7C3@135614|Xanthomonadales 135614|Xanthomonadales S Putative phosphatase (DUF442) - - - - - - - - - - - - DUF442 k141_18538_2 218284.CCDN010000001_gene940 4.42e-85 261.0 COG0404@1|root,COG0404@2|Bacteria,1TRKX@1239|Firmicutes,4H9MX@91061|Bacilli,1ZAS5@1386|Bacillus 91061|Bacilli E The glycine cleavage system catalyzes the degradation of glycine gcvT - 2.1.2.10 ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 M00532 R01221,R02300,R04125 RC00022,RC00069,RC00183,RC02834 ko00000,ko00001,ko00002,ko01000 - - - GCV_T,GCV_T_C k141_12675_1 218284.CCDN010000008_gene4135 4.43e-167 471.0 COG0448@1|root,COG0448@2|Bacteria,1TPZ3@1239|Firmicutes,4H9UQ@91061|Bacilli,1ZBVM@1386|Bacillus 91061|Bacilli G Glucose-1-phosphate adenylyltransferase, GlgD subunit glgD - 2.7.7.27 ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transferase k141_12675_2 218284.CCDN010000008_gene4134 1.38e-83 258.0 COG0448@1|root,COG0448@2|Bacteria,1TNZW@1239|Firmicutes,4HAZX@91061|Bacilli,1ZCF2@1386|Bacillus 91061|Bacilli G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans glgC GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008878,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0070566,GO:0071704,GO:1901576 2.7.7.27 ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transferase k141_33905_1 1042377.AFPJ01000019_gene2519 1.55e-91 284.0 COG0438@1|root,COG0438@2|Bacteria,1MUTA@1224|Proteobacteria,1RS31@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Glycosyl transferase - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 k141_17205_1 321846.PS417_23300 2.31e-57 181.0 arCOG12631@1|root,3172B@2|Bacteria,1RH7M@1224|Proteobacteria,1S7J6@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Bacterial PH domain - - - - - - - - - - - - bPH_1 k141_17205_2 1128912.GMES_1765 2.35e-111 335.0 COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,1S1PK@1236|Gammaproteobacteria,46AFC@72275|Alteromonadaceae 1236|Gammaproteobacteria V Beta-lactamase - - - - - - - - - - - - Beta-lactamase k141_5463_1 1504981.KO116_4252 2.59e-17 80.5 COG3485@1|root,COG3485@2|Bacteria,1MX7W@1224|Proteobacteria,1RP3H@1236|Gammaproteobacteria,1XMKZ@135619|Oceanospirillales 135619|Oceanospirillales Q PFAM intradiol ring-cleavage dioxygenase - - 1.13.11.1 ko:K03381 ko00361,ko00362,ko00364,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00364,map00623,map01100,map01120,map01220 M00568 R00817,R04258,R05299,R08114,R08115,R09134 RC00388,RC00535,RC01366 ko00000,ko00001,ko00002,ko01000 - - - Dioxygenase_C,Dioxygenase_N k141_5463_2 1121943.KB900016_gene369 2.71e-81 254.0 COG4638@1|root,COG4638@2|Bacteria,1N6MJ@1224|Proteobacteria,1RYGT@1236|Gammaproteobacteria,1XNCS@135619|Oceanospirillales 135619|Oceanospirillales P PFAM Aromatic-ring-hydroxylating dioxygenase, alpha subunit - - 1.14.12.10 ko:K05549 ko00362,ko00364,ko00622,ko01100,ko01120,ko01220,map00362,map00364,map00622,map01100,map01120,map01220 M00551 R05290,R05291,R05428,R05621,R05622,R05665,R08100,R08101,R08108,R08109,R08110 RC00270,RC01378,RC01450,RC01910 br01602,ko00000,ko00001,ko00002,ko01000 - - - Rieske,Ring_hydroxyl_A k141_35139_1 1042377.AFPJ01000009_gene240 4.39e-132 391.0 COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,1RNIY@1236|Gammaproteobacteria,4659T@72275|Alteromonadaceae 1236|Gammaproteobacteria E Aminotransferase class-V - - - - - - - - - - - - Aminotran_5 k141_16044_1 1042377.AFPJ01000024_gene816 8.26e-49 164.0 COG0705@1|root,COG0705@2|Bacteria,1MYPM@1224|Proteobacteria,1RN1K@1236|Gammaproteobacteria,463ZC@72275|Alteromonadaceae 1236|Gammaproteobacteria S membrane protein (homolog of Drosophila rhomboid) glpG GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019219,GO:0019222,GO:0019538,GO:0031224,GO:0031226,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042802,GO:0043170,GO:0043565,GO:0044212,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:0140096,GO:1901363,GO:1901564,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - ko:K02441 - - - - ko00000 - - - NRho,Rhomboid,Rhomboid_N k141_6591_1 358396.C445_12026 1.13e-30 123.0 COG3174@1|root,arCOG04203@2157|Archaea,2XT0W@28890|Euryarchaeota,23UFT@183963|Halobacteria 183963|Halobacteria P Domain of unknown function (DUF4010) - - - - - - - - - - - - DUF4010,MgtC k141_19665_1 1294265.JCM21738_4277 7.99e-45 152.0 COG2755@1|root,COG2755@2|Bacteria,1V2R0@1239|Firmicutes,4HI9B@91061|Bacilli,1ZFY5@1386|Bacillus 91061|Bacilli E GDSL-like Lipase/Acylhydrolase ypmR - - - - - - - - - - - Cu_amine_oxidN1,Lipase_GDSL_2 k141_19665_2 1340434.AXVA01000020_gene1380 6.56e-08 50.4 2FKT2@1|root,34CDK@2|Bacteria,1W2TM@1239|Firmicutes,4I1BE@91061|Bacilli,1ZKMZ@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_14796_1 866895.HBHAL_2238 3.22e-40 138.0 COG1670@1|root,COG1670@2|Bacteria,1V485@1239|Firmicutes,4HHFN@91061|Bacilli,3NF14@45667|Halobacillus 91061|Bacilli J Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1 k141_14796_2 218284.CCDN010000001_gene1624 2.26e-22 90.9 28K3D@1|root,2Z9SI@2|Bacteria,1UZKH@1239|Firmicutes,4HDH6@91061|Bacilli,1ZI4E@1386|Bacillus 91061|Bacilli S MEDS: MEthanogen/methylotroph, DcmR Sensory domain - - - - - - - - - - - - MEDS k141_26996_1 1510531.JQJJ01000009_gene1296 3.48e-22 97.8 28HF6@1|root,2Z7RB@2|Bacteria,1P254@1224|Proteobacteria,2TSDA@28211|Alphaproteobacteria,3JS78@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Alginate export - - - - - - - - - - - - Alginate_exp k141_10254_1 1479238.JQMZ01000001_gene1402 3.39e-41 148.0 COG0388@1|root,COG0388@2|Bacteria,1RIJ5@1224|Proteobacteria,2USQC@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Carbon-nitrogen hydrolase - - - - - - - - - - - - CN_hydrolase k141_10254_2 1117647.M5M_13340 3.9e-193 552.0 COG1231@1|root,COG1231@2|Bacteria,1P3D9@1224|Proteobacteria,1S0H2@1236|Gammaproteobacteria,1JA3E@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Flavin containing amine oxidoreductase - - 1.4.3.4 ko:K00274 ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034 M00135 R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354 RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713 ko00000,ko00001,ko00002,ko01000 - - - Amino_oxidase k141_10254_3 394221.Mmar10_0142 1.05e-99 308.0 COG4690@1|root,COG4690@2|Bacteria,1RBRZ@1224|Proteobacteria,2U9EN@28211|Alphaproteobacteria 28211|Alphaproteobacteria E dipeptidase activity - - - - - - - - - - - - - k141_19862_1 1294265.JCM21738_2877 4.03e-82 253.0 COG0477@1|root,COG0477@2|Bacteria,1TTC8@1239|Firmicutes,4HAPZ@91061|Bacilli,1ZAQ7@1386|Bacillus 91061|Bacilli EGP Major facilitator superfamily yqgE - - ko:K08222 - - - - ko00000,ko02000 2.A.1.33 - - MFS_1 k141_23555_1 1131730.BAVI_11274 3.19e-65 208.0 COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,4HATR@91061|Bacilli,1ZCAV@1386|Bacillus 91061|Bacilli P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components appB - - ko:K02033 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 k141_883_1 1462526.BN990_00740 2.26e-09 57.8 COG0673@1|root,COG0673@2|Bacteria,1TQ72@1239|Firmicutes,4HAGN@91061|Bacilli,4C6BT@84406|Virgibacillus 91061|Bacilli S Oxidoreductase family, C-terminal alpha/beta domain - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C k141_883_2 218284.CCDN010000001_gene1968 7.9e-140 402.0 COG0673@1|root,COG0673@2|Bacteria,1TQ72@1239|Firmicutes,4HCS4@91061|Bacilli,1ZCPA@1386|Bacillus 91061|Bacilli S Oxidoreductase family, C-terminal alpha/beta domain - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C k141_14142_1 1116375.VEJY3_10800 2.17e-269 750.0 COG0366@1|root,COG0366@2|Bacteria,1MVKX@1224|Proteobacteria,1RQHM@1236|Gammaproteobacteria,1XT2H@135623|Vibrionales 135623|Vibrionales G Belongs to the glycosyl hydrolase 13 family malZ - 3.2.1.20 ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00028,R00801,R00802,R06087,R06088 RC00028,RC00049,RC00077 ko00000,ko00001,ko01000 - GH31 - Alpha-amylase,Alpha-amylase_N,DUF3459,Malt_amylase_C k141_14142_2 1116375.VEJY3_10790 2.32e-233 642.0 COG0042@1|root,COG0042@2|Bacteria,1MUSM@1224|Proteobacteria,1RMMM@1236|Gammaproteobacteria,1XTYF@135623|Vibrionales 135623|Vibrionales J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs dusC - - ko:K05541 - - - - ko00000,ko01000,ko03016 - - - Dus k141_14142_3 674977.VMC_28250 1.22e-128 367.0 COG3012@1|root,COG3012@2|Bacteria,1QN8B@1224|Proteobacteria,1T25E@1236|Gammaproteobacteria,1XWAD@135623|Vibrionales 135623|Vibrionales S metal-binding protein related to the C-terminal domain of SecA - - - ko:K07039 - - - - ko00000 - - - SEC-C,UPF0149 k141_14142_4 223926.28807066 8.98e-114 327.0 COG1495@1|root,COG1495@2|Bacteria,1RIJE@1224|Proteobacteria,1S6WD@1236|Gammaproteobacteria,1XV2K@135623|Vibrionales 135623|Vibrionales C Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein dsbB GO:0006457,GO:0008150,GO:0009987 - ko:K03611 - - - - ko00000,ko03110 5.A.2.1 - - DsbB k141_14142_5 1116375.VEJY3_10775 2.36e-185 527.0 COG3067@1|root,COG3067@2|Bacteria,1MV0F@1224|Proteobacteria,1RPE3@1236|Gammaproteobacteria,1XT42@135623|Vibrionales 135623|Vibrionales P ) H( ) antiporter that extrudes sodium in exchange for external protons nhaB GO:0003674,GO:0005215,GO:0005451,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015491,GO:0015672,GO:0016020,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0035725,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0099516,GO:1902600 - ko:K03314 - - - - ko00000,ko02000 2.A.34.1 - - NhaB k141_5690_1 1347369.CCAD010000019_gene1386 5.88e-29 114.0 COG1668@1|root,COG1668@2|Bacteria,1V8IQ@1239|Firmicutes,4IQWM@91061|Bacilli,1ZRP0@1386|Bacillus 91061|Bacilli CP ABC-2 family transporter protein - - - ko:K09696 ko02010,ko02020,map02010,map02020 M00253 - - ko00000,ko00001,ko00002,ko02000 3.A.1.115 - iYO844.BSU02760 ABC2_membrane_2 k141_5690_2 218284.CCDN010000001_gene1657 3.87e-55 177.0 COG4555@1|root,COG4555@2|Bacteria,1UHYH@1239|Firmicutes,4ISGA@91061|Bacilli,1ZC0Y@1386|Bacillus 91061|Bacilli CP ATPases associated with a variety of cellular activities natA - 3.6.3.7 ko:K01990,ko:K09697 ko02010,ko02020,map02010,map02020 M00253,M00254 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.115 - iYO844.BSU02750 ABC_tran k141_29296_1 1122194.AUHU01000006_gene549 4.46e-94 290.0 COG2010@1|root,COG2010@2|Bacteria,1MV6D@1224|Proteobacteria,1RMYF@1236|Gammaproteobacteria,466XG@72275|Alteromonadaceae 1236|Gammaproteobacteria C Cytochrome C oxidase, cbb3-type, subunit III - - - - - - - - - - - - Cytochrom_C,Cytochrome_CBB3 k141_36278_1 1042377.AFPJ01000028_gene2204 1.94e-44 152.0 COG3713@1|root,COG3713@2|Bacteria,1N3RD@1224|Proteobacteria,1SAIX@1236|Gammaproteobacteria,468UZ@72275|Alteromonadaceae 1236|Gammaproteobacteria M MltA-interacting protein MipA - - - ko:K07274 - - - - ko00000,ko02000 9.B.99.1 - - MipA k141_19863_1 1196031.ALEG01000033_gene3009 1.93e-86 271.0 COG1680@1|root,COG1680@2|Bacteria,1U828@1239|Firmicutes,4HA0Q@91061|Bacilli,1ZBJ0@1386|Bacillus 91061|Bacilli V Belongs to the UPF0214 family estB - 3.4.16.4 ko:K21469 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - Beta-lactamase,Peptidase_M6 k141_884_1 1347369.CCAD010000019_gene1399 5.25e-98 293.0 COG4606@1|root,COG4606@2|Bacteria,1TSQX@1239|Firmicutes,4H9P2@91061|Bacilli,1ZB32@1386|Bacillus 91061|Bacilli P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily fatD - - ko:K02015 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - FecCD k141_31467_1 1120970.AUBZ01000026_gene2161 5.45e-76 244.0 COG0006@1|root,COG0006@2|Bacteria,1MURT@1224|Proteobacteria,1RMKT@1236|Gammaproteobacteria,465D3@72275|Alteromonadaceae 1236|Gammaproteobacteria E Splits dipeptides with a prolyl residue in the C- terminal position pepQ GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009056,GO:0009987,GO:0016787,GO:0016805,GO:0019538,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0070573,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.4.13.9 ko:K01271 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M24 k141_9240_1 1121939.L861_10835 6.33e-147 418.0 COG5473@1|root,COG5473@2|Bacteria,1MVRU@1224|Proteobacteria,1RPJA@1236|Gammaproteobacteria,1XM9N@135619|Oceanospirillales 135619|Oceanospirillales S membrane - - - - - - - - - - - - DUF2189 k141_25893_1 491915.Aflv_0347 1.39e-133 397.0 COG1620@1|root,COG1620@2|Bacteria,1TQNM@1239|Firmicutes,4HAF3@91061|Bacilli 91061|Bacilli C L-lactate permease - - - ko:K03303 - - - - ko00000,ko02000 2.A.14 - - Lactate_perm k141_19864_1 502025.Hoch_3427 2.81e-07 52.4 COG0784@1|root,COG1352@1|root,COG2201@1|root,COG2202@1|root,COG2203@1|root,COG4251@1|root,COG0784@2|Bacteria,COG1352@2|Bacteria,COG2201@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4251@2|Bacteria,1NC9X@1224|Proteobacteria,43BU6@68525|delta/epsilon subdivisions,2X7XX@28221|Deltaproteobacteria 28221|Deltaproteobacteria T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA,PAS_4,Response_reg k141_19864_2 218284.CCDN010000006_gene3550 2.53e-64 206.0 COG0225@1|root,COG0229@1|root,COG0225@2|Bacteria,COG0229@2|Bacteria,1TQ3E@1239|Firmicutes,4HAIV@91061|Bacilli,1ZDD3@1386|Bacillus 91061|Bacilli O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine - - 1.8.4.11,1.8.4.12 ko:K12267 - - - - ko00000,ko01000 - - - PMSR,SelR k141_22226_2 1453501.JELR01000001_gene2142 1.34e-128 380.0 COG1115@1|root,COG1115@2|Bacteria,1MUI3@1224|Proteobacteria,1RMNF@1236|Gammaproteobacteria,464HE@72275|Alteromonadaceae 1236|Gammaproteobacteria E alanine symporter yaaJ GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03310 - - - - ko00000 2.A.25 - iEcE24377_1341.EcE24377A_0007 Na_Ala_symp k141_885_1 1453501.JELR01000001_gene1931 2.03e-108 337.0 COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,1RN5T@1236|Gammaproteobacteria,464WE@72275|Alteromonadaceae 1236|Gammaproteobacteria O Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen glnD GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008773,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019538,GO:0019752,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0070569,GO:0071704,GO:0140096,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.59 ko:K00990 ko02020,map02020 - - - ko00000,ko00001,ko01000 - - - ACT,GlnD_UR_UTase,HD,NTP_transf_2 k141_34087_2 642227.HA49_07770 3.49e-28 111.0 COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,1RNQK@1236|Gammaproteobacteria,4BU5Z@82986|Tatumella 1236|Gammaproteobacteria E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline proC GO:0003674,GO:0003824,GO:0004735,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0017144,GO:0018130,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0055114,GO:0055129,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 - - iSBO_1134.SBO_0282,ic_1306.c0493 F420_oxidored,P5CR_dimer k141_14982_1 218284.CCDN010000004_gene3038 3.55e-38 135.0 COG0705@1|root,COG0705@2|Bacteria,1UYXN@1239|Firmicutes,4HCIU@91061|Bacilli,1ZRQJ@1386|Bacillus 91061|Bacilli S membrane protein (homolog of Drosophila rhomboid) ydcA - 3.4.21.105 ko:K19225 - - - - ko00000,ko01000,ko01002 - - - Rhomboid k141_4310_2 866895.HBHAL_4125 5.92e-105 319.0 COG1966@1|root,COG1966@2|Bacteria,1TQN8@1239|Firmicutes,4H9SU@91061|Bacilli,3NE3X@45667|Halobacillus 91061|Bacilli T 5TM C-terminal transporter carbon starvation CstA cstA_1 - - ko:K06200 - - - - ko00000 - - - CstA,CstA_5TM k141_25894_1 574375.BAGA_06545 4.16e-38 146.0 COG1404@1|root,COG1404@2|Bacteria,1TPH1@1239|Firmicutes,4HBQH@91061|Bacilli,1ZBS0@1386|Bacillus 91061|Bacilli O Belongs to the peptidase S8 family prtS - 3.4.21.110,3.4.21.96 ko:K01361,ko:K08652 - - - - ko00000,ko01000,ko01002,ko03110 - - - FIVAR,Gram_pos_anchor,Inhibitor_I9,PA,Peptidase_S8,SLH,YSIRK_signal,fn3_5 k141_24617_1 223926.28805758 1.23e-150 426.0 COG1261@1|root,COG1261@2|Bacteria,1N1SA@1224|Proteobacteria,1S8SQ@1236|Gammaproteobacteria,1XSM2@135623|Vibrionales 135623|Vibrionales N Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly flgA - - ko:K02386 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - ChapFlgA k141_24617_2 674977.VMC_09800 1.12e-49 159.0 COG2747@1|root,COG2747@2|Bacteria,1NGJA@1224|Proteobacteria,1SGQ4@1236|Gammaproteobacteria,1XYEH@135623|Vibrionales 135623|Vibrionales N COG2747 Negative regulator of flagellin synthesis (anti-sigma28 factor) flgM - - ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 - - - ko00000,ko00001,ko02035 - - - FlgM k141_24617_3 223926.28805756 1.75e-84 250.0 COG3418@1|root,33AIS@2|Bacteria,1NH78@1224|Proteobacteria,1SGPM@1236|Gammaproteobacteria,1XXGG@135623|Vibrionales 135623|Vibrionales NOU FlgN protein flgN - - ko:K02399 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FlgN k141_29297_1 218284.CCDN010000001_gene1162 9.25e-190 531.0 COG0116@1|root,COG0116@2|Bacteria,1TP0X@1239|Firmicutes,4HBKY@91061|Bacilli,1ZBJB@1386|Bacillus 91061|Bacilli L Belongs to the methyltransferase superfamily ypsC GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 - ko:K07444 - - - - ko00000,ko01000 - - - THUMP,UPF0020 k141_20900_1 218284.CCDN010000001_gene449 3.87e-93 299.0 COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,4HAFP@91061|Bacilli,1ZBJ3@1386|Bacillus 91061|Bacilli V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran k141_17351_1 223926.28805652 1.19e-220 644.0 COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,1RMRN@1236|Gammaproteobacteria,1XTXA@135623|Vibrionales 135623|Vibrionales F Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate purL GO:0003674,GO:0003824,GO:0004642,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - AIRS_C,GATase_5 k141_17351_2 674977.VMC_07780 2.27e-39 133.0 2EK51@1|root,33DVG@2|Bacteria,1N6U3@1224|Proteobacteria,1SE54@1236|Gammaproteobacteria,1XZ0Y@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF3622) - - - - - - - - - - - - DUF3622 k141_17351_3 1116375.VEJY3_03075 1.39e-237 655.0 COG3608@1|root,COG3608@2|Bacteria,1MUAA@1224|Proteobacteria,1RNQQ@1236|Gammaproteobacteria,1XTI2@135623|Vibrionales 135623|Vibrionales S Succinylglutamate desuccinylase aspartoacylase family protein - - - ko:K06987 - - - - ko00000 - - - AstE_AspA k141_17351_4 1116375.VEJY3_03085 0.0 933.0 COG2195@1|root,COG2195@2|Bacteria,1MUWK@1224|Proteobacteria,1RP5F@1236|Gammaproteobacteria,1XT90@135623|Vibrionales 135623|Vibrionales E aminoacyl-histidine dipeptidase pepD - - ko:K01270 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 k141_17351_5 223926.28805658 1.19e-280 770.0 COG2252@1|root,COG2252@2|Bacteria,1MUV0@1224|Proteobacteria,1RMBE@1236|Gammaproteobacteria,1XUUP@135623|Vibrionales 135623|Vibrionales S COG2252 Permeases yieG - - ko:K06901 - - - - ko00000,ko02000 2.A.1.40 - - Xan_ur_permease k141_17351_6 223926.28805659 9.12e-109 313.0 COG2236@1|root,COG2236@2|Bacteria,1MWNE@1224|Proteobacteria,1RQ4C@1236|Gammaproteobacteria,1XSMG@135623|Vibrionales 135623|Vibrionales F Acts on guanine, xanthine and to a lesser extent hypoxanthine gpt GO:0000310,GO:0003674,GO:0003824,GO:0004422,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006166,GO:0006177,GO:0006188,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032261,GO:0032263,GO:0032264,GO:0032265,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0043094,GO:0043101,GO:0043173,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046040,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097292,GO:0097293,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.22 ko:K00769 ko00230,ko01100,ko01110,map00230,map01100,map01110 - R01229,R02142 RC00063,RC00122 ko00000,ko00001,ko01000 - - - Pribosyltran k141_17351_7 1116375.VEJY3_03100 1.28e-277 761.0 COG1073@1|root,COG1073@2|Bacteria,1N5CG@1224|Proteobacteria,1RR2Y@1236|Gammaproteobacteria,1XSG1@135623|Vibrionales 135623|Vibrionales S Belongs to the UPF0255 family frsA - - ko:K11750 - - - - ko00000,ko01000 - - - DUF1100 k141_17351_8 1219076.N646_2828 4.14e-84 248.0 292QM@1|root,2ZQ8E@2|Bacteria,1N4UT@1224|Proteobacteria,1S3WH@1236|Gammaproteobacteria,1XY3C@135623|Vibrionales 135623|Vibrionales K Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32 crl GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 - ko:K11926 - - - - ko00000,ko03000 - - - Crl k141_17351_9 1116375.VEJY3_03110 2.56e-252 694.0 COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,1RM7X@1236|Gammaproteobacteria,1XTWE@135623|Vibrionales 135623|Vibrionales F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate proB GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 M00015 R00239 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,PUA k141_17351_10 1116375.VEJY3_03115 1.04e-273 751.0 COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,1RMAY@1236|Gammaproteobacteria,1XT6D@135623|Vibrionales 135623|Vibrionales E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate proA GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 M00015 R03313 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_17351_11 1116375.VEJY3_03120 1.26e-99 289.0 COG1327@1|root,COG1327@2|Bacteria,1RE7V@1224|Proteobacteria,1S3P9@1236|Gammaproteobacteria,1XT5J@135623|Vibrionales 135623|Vibrionales K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes nrdR - - ko:K07738 - - - - ko00000,ko03000 - - - ATP-cone k141_17351_12 1116375.VEJY3_03125 1.56e-227 631.0 COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,1RN2M@1236|Gammaproteobacteria,1XST0@135623|Vibrionales 135623|Vibrionales H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate ribD - 1.1.1.193,3.5.4.26 ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 M00125 R03458,R03459 RC00204,RC00933 ko00000,ko00001,ko00002,ko01000 - - - RibD_C,dCMP_cyt_deam_1 k141_17351_13 1116375.VEJY3_03130 4.43e-140 397.0 COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,1RMSY@1236|Gammaproteobacteria,1XTJZ@135623|Vibrionales 135623|Vibrionales H Riboflavin synthase alpha chain ribE - 2.5.1.9 ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00066 RC00958,RC00960 ko00000,ko00001,ko00002,ko01000 - - - Lum_binding k141_17351_14 1219076.N646_2834 1.83e-256 704.0 COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1MU8P@1224|Proteobacteria,1RQ49@1236|Gammaproteobacteria,1XSY7@135623|Vibrionales 135623|Vibrionales H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate ribB - 3.5.4.25,4.1.99.12 ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 M00125,M00840 R00425,R07281 RC00293,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 - - - DHBP_synthase,GTP_cyclohydro2 k141_17351_15 1219076.N646_2835 9.41e-103 298.0 COG0054@1|root,COG0054@2|Bacteria,1RD9J@1224|Proteobacteria,1S3WD@1236|Gammaproteobacteria,1XTEC@135623|Vibrionales 135623|Vibrionales H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin ribH GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R04457 RC00960 ko00000,ko00001,ko00002,ko01000 - - - DMRL_synthase k141_17351_16 223926.28805669 1.39e-99 290.0 COG0781@1|root,COG0781@2|Bacteria,1RHFZ@1224|Proteobacteria,1S6AJ@1236|Gammaproteobacteria,1XSA8@135623|Vibrionales 135623|Vibrionales K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons nusB GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - ko:K03625 - - - - ko00000,ko03009,ko03021 - - - NusB k141_17351_17 223926.28805670 2.45e-127 368.0 COG0611@1|root,COG0611@2|Bacteria,1MU9X@1224|Proteobacteria,1RNHU@1236|Gammaproteobacteria,1XTKW@135623|Vibrionales 135623|Vibrionales F Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 thiL - 2.7.4.16 ko:K00946 ko00730,ko01100,map00730,map01100 M00127 R00617 RC00002 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C k141_14145_1 218284.CCDN010000001_gene959 5.13e-27 105.0 2E6BB@1|root,330Z5@2|Bacteria,1VF3M@1239|Firmicutes,4HH7J@91061|Bacilli,1ZEMQ@1386|Bacillus 91061|Bacilli S stage III sporulation protein AG spoIIIAG - - ko:K06396 - - - - ko00000 - - - - k141_14145_2 218284.CCDN010000001_gene958 9.79e-64 202.0 2E7KE@1|root,3322G@2|Bacteria,1VG6C@1239|Firmicutes,4HNMG@91061|Bacilli,1ZH76@1386|Bacillus 91061|Bacilli S Stage III sporulation protein AF (Spore_III_AF) spoIIIAF - - ko:K06395 - - - - ko00000 - - - Spore_III_AF k141_37499_1 1215092.PA6_027_01190 6.09e-51 182.0 COG2373@1|root,COG2373@2|Bacteria,1Q2SN@1224|Proteobacteria,1S1CA@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q Animal haem peroxidase - - - - - - - - - - - - An_peroxidase k141_25895_2 1042377.AFPJ01000010_gene1464 2.32e-17 83.2 COG2304@1|root,COG2304@2|Bacteria,1MW8K@1224|Proteobacteria,1RNU3@1236|Gammaproteobacteria,46676@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein containing a von Willebrand factor type A (vWA) domain - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - VIT,VWA_3 k141_18830_1 983545.Glaag_4044 6.11e-203 612.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria,4652I@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec k141_9242_1 1453501.JELR01000002_gene952 7.65e-63 221.0 COG0643@1|root,COG0745@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,4650G@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0643 Chemotaxis protein histidine kinase and related kinases chpA - - ko:K02487,ko:K06596 ko02020,ko02025,map02020,map02025 M00507 - - ko00000,ko00001,ko00002,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg k141_23556_1 1116375.VEJY3_19861 5.27e-143 407.0 COG0583@1|root,COG0583@2|Bacteria,1MZTA@1224|Proteobacteria,1RN7R@1236|Gammaproteobacteria,1XSKB@135623|Vibrionales 135623|Vibrionales K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_23556_2 1280001.BAOA01000138_gene2049 1.79e-236 671.0 COG1629@1|root,COG4771@2|Bacteria,1MX42@1224|Proteobacteria,1RQ2K@1236|Gammaproteobacteria,1XUY7@135623|Vibrionales 135623|Vibrionales P COG1629 Outer membrane receptor proteins, mostly Fe transport hutA - - ko:K16087 - - - - ko00000,ko02000 1.B.14.2 - - Plug,TonB_dep_Rec k141_14984_1 317655.Sala_1180 4.57e-56 191.0 COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,2TR96@28211|Alphaproteobacteria,2K0TE@204457|Sphingomonadales 204457|Sphingomonadales IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - 6.2.1.44 ko:K00666,ko:K20034 ko00920,map00920 - R10820 RC00004,RC00014 ko00000,ko00001,ko01000,ko01004 - - - AMP-binding,AMP-binding_C k141_27239_1 1453501.JELR01000001_gene2677 6.17e-127 364.0 COG0755@1|root,COG0755@2|Bacteria,1MU61@1224|Proteobacteria,1RP3R@1236|Gammaproteobacteria,464ZM@72275|Alteromonadaceae 1236|Gammaproteobacteria O Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes ccmC GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008152,GO:0015886,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051181,GO:0051234,GO:0055114,GO:0071702,GO:0071705,GO:0071944,GO:1901678 - ko:K02195 ko02010,map02010 M00259 - - ko00000,ko00001,ko00002,ko02000 3.A.1.107 - iECDH1ME8569_1439.ECDH1ME8569_2134,iSFV_1184.SFV_2275,iSFxv_1172.SFxv_2517,iUTI89_1310.UTI89_C2477,ic_1306.c2736 Cytochrom_C_asm k141_27239_2 1279017.AQYJ01000029_gene3371 9.21e-118 342.0 COG2386@1|root,COG2386@2|Bacteria,1NJB0@1224|Proteobacteria,1RRFJ@1236|Gammaproteobacteria,466DX@72275|Alteromonadaceae 1236|Gammaproteobacteria O Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes ccmB GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0031224,GO:0031226,GO:0032991,GO:0042623,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - ko:K02194 ko02010,map02010 M00259 - - ko00000,ko00001,ko00002,ko02000 3.A.1.107 - iECO111_1330.ECO111_2936,iYL1228.KPN_02080 CcmB k141_27239_3 1279017.AQYJ01000029_gene3370 5.57e-96 286.0 COG4133@1|root,COG4133@2|Bacteria,1MZPC@1224|Proteobacteria,1S3R2@1236|Gammaproteobacteria,466VK@72275|Alteromonadaceae 1236|Gammaproteobacteria O once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system ccmA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0009898,GO:0015232,GO:0015886,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019897,GO:0019898,GO:0022857,GO:0031224,GO:0031234,GO:0032991,GO:0042623,GO:0043190,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051181,GO:0051184,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098533,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:1901678,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.41 ko:K02193 ko02010,map02010 M00259 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.107 - iAPECO1_1312.APECO1_4358,iECED1_1282.ECED1_2666,iECS88_1305.ECS88_2348,iECUMN_1333.ECUMN_2536,iLF82_1304.LF82_0273,iNRG857_1313.NRG857_11170,iUMN146_1321.UM146_05800,iUTI89_1310.UTI89_C2479 ABC_tran k141_27239_4 95619.PM1_0219455 6.95e-86 285.0 COG0745@1|root,COG2172@1|root,COG2208@1|root,COG0745@2|Bacteria,COG2172@2|Bacteria,COG2208@2|Bacteria,1N4K5@1224|Proteobacteria,1RNYP@1236|Gammaproteobacteria 1236|Gammaproteobacteria T response regulator rsbU - - ko:K20977 ko02020,ko02025,map02020,map02025 M00820 - - ko00000,ko00001,ko00002,ko02022 - - - HATPase_c_2,Response_reg,SpoIIE k141_9263_1 218284.CCDN010000002_gene2724 4.88e-22 94.4 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1TQ85@1239|Firmicutes,4HAC0@91061|Bacilli,1ZR0Z@1386|Bacillus 91061|Bacilli EU Dienelactone hydrolase family - - - - - - - - - - - - PD40,Peptidase_S9,Peptidase_S9_N k141_27920_1 1134413.ANNK01000002_gene2926 1.14e-290 800.0 COG0579@1|root,COG0579@2|Bacteria,1TNZY@1239|Firmicutes,4H9PS@91061|Bacilli,1ZBRT@1386|Bacillus 91061|Bacilli S malate quinone oxidoreductase mqo - 1.1.5.4 ko:K00116 ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00009,M00011 R00360,R00361,R01257 RC00031 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS12375 Mqo k141_23593_1 1348635.BBJY01000016_gene3964 1.06e-105 315.0 COG1172@1|root,COG1172@2|Bacteria,1MX7D@1224|Proteobacteria,1RNTS@1236|Gammaproteobacteria,1XTC8@135623|Vibrionales 135623|Vibrionales G Belongs to the binding-protein-dependent transport system permease family - - - ko:K02057 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - BPD_transp_2 k141_1876_1 218284.CCDN010000008_gene4146 4.81e-159 459.0 COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HACS@91061|Bacilli,1ZB6H@1386|Bacillus 91061|Bacilli H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily menE - 6.2.1.26 ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R04030 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - AMP-binding,AMP-binding_C k141_17373_2 1042377.AFPJ01000048_gene2675 8.43e-82 246.0 COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,1S24R@1236|Gammaproteobacteria,466CX@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the UPF0312 family yceI - - - - - - - - - - - YceI k141_34104_1 1123320.KB889676_gene2888 6.98e-12 70.5 COG1461@1|root,COG1461@2|Bacteria,2GKII@201174|Actinobacteria 201174|Actinobacteria S Dihydroxyacetone kinase dak3 - - ko:K07030 - - - - ko00000 - - - Dak1_2,Dak2 k141_35368_1 218284.CCDN010000002_gene2070 8.64e-77 251.0 COG1199@1|root,COG1199@2|Bacteria,1TPNB@1239|Firmicutes,4HD6T@91061|Bacilli,1ZAUN@1386|Bacillus 91061|Bacilli KL DEAD_2 uvrB3 - 3.1.12.1 ko:K07464 - - - - ko00000,ko01000,ko02048 - - - DEAD,DEAD_2,HBB,Helicase_C_2,PDDEXK_1 k141_18845_1 1340434.AXVA01000005_gene4896 3.46e-53 174.0 COG0095@1|root,COG0095@2|Bacteria,1TQ5U@1239|Firmicutes,4HABG@91061|Bacilli,1ZBG2@1386|Bacillus 91061|Bacilli H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation lipM GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 6.3.1.20 ko:K03800 ko00785,ko01100,map00785,map01100 - R07770,R07771,R11143 RC00043,RC00070,RC00090,RC00992,RC02896 ko00000,ko00001,ko01000 - - - BPL_LplA_LipB k141_6828_1 1209072.ALBT01000012_gene3289 1.42e-50 178.0 COG0642@1|root,COG2205@2|Bacteria,1N1Z2@1224|Proteobacteria,1RPG9@1236|Gammaproteobacteria,1FH2A@10|Cellvibrio 1236|Gammaproteobacteria T His Kinase A (phosphoacceptor) domain qseC - 2.7.13.3 ko:K07645 ko02020,ko02024,map02020,map02024 M00453 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - 2CSK_N,HATPase_c,HisKA k141_25912_1 1294265.JCM21738_5417 8.92e-122 356.0 2BAY9@1|root,324E2@2|Bacteria,1V8TN@1239|Firmicutes,4HJ42@91061|Bacilli,1ZESD@1386|Bacillus 91061|Bacilli - - yqgU - - - - - - - - - - - - k141_9265_1 1294265.JCM21738_5415 8.43e-107 325.0 COG1368@1|root,COG1368@2|Bacteria,1TRMA@1239|Firmicutes,4H9S0@91061|Bacilli,1ZBBV@1386|Bacillus 91061|Bacilli M Belongs to the LTA synthase family yqgS - - ko:K01138 - - - - ko00000,ko01000 - - - Sulfatase k141_36296_1 1279017.AQYJ01000021_gene2783 3.79e-95 283.0 COG2755@1|root,COG2755@2|Bacteria,1RCXZ@1224|Proteobacteria,1S3QU@1236|Gammaproteobacteria,466ZZ@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG2755 Lysophospholipase L1 and related esterases tesA GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016289,GO:0016290,GO:0016298,GO:0016787,GO:0016788,GO:0016790,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0047617,GO:0052689,GO:0071704,GO:0140096,GO:1901564 3.1.1.5 ko:K10804 ko01040,map01040 - - - ko00000,ko00001,ko01000,ko01004 - - iECED1_1282.ECED1_0521,iLF82_1304.LF82_2242,iNRG857_1313.NRG857_02365 Lipase_GDSL_2 k141_36296_2 1279017.AQYJ01000021_gene2784 2.65e-193 539.0 COG0037@1|root,COG0037@2|Bacteria,1MW5Q@1224|Proteobacteria,1RN2H@1236|Gammaproteobacteria,464FD@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system ttcA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0016783,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360 - ko:K14058 - - - - ko00000,ko03016 - - - ATP_bind_3 k141_36296_3 1137799.GZ78_15635 3.84e-54 177.0 2DZF6@1|root,32V95@2|Bacteria,1N4GD@1224|Proteobacteria,1SAP2@1236|Gammaproteobacteria,1XMNX@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_19885_2 1279017.AQYJ01000027_gene1996 2.55e-101 297.0 COG2840@1|root,COG2840@2|Bacteria,1RH34@1224|Proteobacteria,1S6B5@1236|Gammaproteobacteria,466YR@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - Smr k141_19885_4 1279017.AQYJ01000027_gene1994 3.84e-15 70.9 COG0824@1|root,COG0824@2|Bacteria,1RI3X@1224|Proteobacteria,1SAHQ@1236|Gammaproteobacteria,46DIX@72275|Alteromonadaceae 1236|Gammaproteobacteria S Thioesterase superfamily - - - ko:K07107 - - - - ko00000,ko01000 - - - 4HBT,4HBT_2,Acyl-ACP_TE k141_23594_1 218284.CCDN010000002_gene2946 7.97e-76 235.0 COG4586@1|root,COG4586@2|Bacteria,1TP1N@1239|Firmicutes,4H9NR@91061|Bacilli,1ZBGB@1386|Bacillus 91061|Bacilli S transport system, ATPase component drrA1 - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_11641_1 218284.CCDN010000008_gene4227 1.78e-105 310.0 COG1360@1|root,COG1360@2|Bacteria,1V8KE@1239|Firmicutes,4H9MD@91061|Bacilli,1ZQQB@1386|Bacillus 91061|Bacilli N Flagellar motor protein ytxE - - ko:K02557 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - MotB_plug,OmpA k141_11641_2 1462526.BN990_01584 5.4e-25 100.0 COG1291@1|root,COG1291@2|Bacteria,1TRH1@1239|Firmicutes,4HAXG@91061|Bacilli,4C4J4@84406|Virgibacillus 91061|Bacilli N MotA/TolQ/ExbB proton channel family motP GO:0001539,GO:0005575,GO:0005623,GO:0005886,GO:0006928,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0040011,GO:0044425,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071944,GO:0071973,GO:0071978,GO:0097588 - ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - MotA_ExbB k141_37518_1 218284.CCDN010000002_gene2858 4.61e-97 300.0 COG1657@1|root,COG1657@2|Bacteria,1TRRG@1239|Firmicutes,4HA2Q@91061|Bacilli,1ZBBW@1386|Bacillus 91061|Bacilli I COG1657 Squalene cyclase sqhC - 4.2.1.137 ko:K18115 - - - - ko00000,ko01000 - - - SQHop_cyclase_C,SQHop_cyclase_N k141_31486_1 218284.CCDN010000002_gene2850 1.88e-86 258.0 COG5553@1|root,COG5553@2|Bacteria,1VFPC@1239|Firmicutes,4HPUH@91061|Bacilli,1ZFM7@1386|Bacillus 91061|Bacilli S Cysteine dioxygenase type I cdoA - 1.13.11.20 ko:K00456 ko00270,ko00430,ko01100,map00270,map00430,map01100 - R00893 RC00404 ko00000,ko00001,ko01000 - - - CDO_I k141_14167_1 218284.CCDN010000005_gene3448 0.0 891.0 COG1009@1|root,COG2111@1|root,COG1009@2|Bacteria,COG2111@2|Bacteria,1TQW4@1239|Firmicutes,4H9YR@91061|Bacilli,1ZAZ0@1386|Bacillus 91061|Bacilli CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit mrpA - - ko:K05565 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - DUF4040,Proton_antipo_M,Proton_antipo_N k141_11642_1 935837.JAEK01000020_gene591 1.4e-70 218.0 29Y0M@1|root,30JTI@2|Bacteria,1VEVD@1239|Firmicutes,4IRVM@91061|Bacilli 91061|Bacilli S Family of unknown function (DUF5317) - - - - - - - - - - - - DUF5317 k141_9266_1 1196031.ALEG01000033_gene3010 2.59e-97 305.0 COG1472@1|root,COG1472@2|Bacteria,1TP63@1239|Firmicutes,4HBDB@91061|Bacilli,1ZCGR@1386|Bacillus 91061|Bacilli G Belongs to the glycosyl hydrolase 3 family ybbD - 3.2.1.52 ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 M00628 R00022,R05963,R07809,R07810,R10831 RC00049 ko00000,ko00001,ko00002,ko01000 - - - Big_2,Glyco_hydro_3,Glyco_hydro_3_C,Gram_pos_anchor,SLH k141_34105_1 1121441.AUCX01000014_gene507 9.63e-13 75.5 COG5563@1|root,COG5563@2|Bacteria,1Q0JE@1224|Proteobacteria,430IH@68525|delta/epsilon subdivisions,2X0GF@28221|Deltaproteobacteria,2MD65@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k141_26147_1 933115.GPDM_02170 1.26e-78 245.0 COG0477@1|root,COG2814@2|Bacteria,1UXXX@1239|Firmicutes,4HC83@91061|Bacilli,26GPY@186818|Planococcaceae 91061|Bacilli EGP Sugar (and other) transporter - - - - - - - - - - - - MFS_1,Sugar_tr k141_1145_1 1307436.PBF_04843 1.2e-78 243.0 COG0840@1|root,COG0840@2|Bacteria,1VTI2@1239|Firmicutes,4HV5F@91061|Bacilli,1ZQNP@1386|Bacillus 91061|Bacilli NT PAS fold - - - - - - - - - - - - MCPsignal,PAS_4,PAS_9 k141_5891_1 1279017.AQYJ01000020_gene1338 5.08e-58 184.0 2FAHI@1|root,342RK@2|Bacteria,1NXJ2@1224|Proteobacteria,1SQ04@1236|Gammaproteobacteria 1236|Gammaproteobacteria S COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) - - - - - - - - - - - - - k141_35604_2 218284.CCDN010000005_gene3292 2.33e-115 334.0 COG2761@1|root,COG2761@2|Bacteria,1TQ8K@1239|Firmicutes,4HAI8@91061|Bacilli,1ZATS@1386|Bacillus 91061|Bacilli Q dithiol-disulfide isomerase involved in polyketide biosynthesis yjbH - - - - - - - - - - - Thioredoxin_5 k141_29526_1 946235.CAER01000056_gene2914 3.47e-13 66.2 2E87Y@1|root,332M1@2|Bacteria,1U2F1@1239|Firmicutes,4IC0M@91061|Bacilli,23MAM@182709|Oceanobacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_17533_2 1279017.AQYJ01000027_gene1716 3.55e-173 491.0 COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,1RN5G@1236|Gammaproteobacteria,46ACM@72275|Alteromonadaceae 1236|Gammaproteobacteria S ATPase family associated with various cellular activities (AAA) - - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 k141_20119_1 218284.CCDN010000004_gene3125 3.17e-167 485.0 COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,4HADT@91061|Bacilli,1ZCKV@1386|Bacillus 91061|Bacilli KT Sigma-54 interaction domain - - - - - - - - - - - - HTH_12,HTH_8,PAS,PAS_9,Sigma54_activat k141_13019_1 218284.CCDN010000001_gene446 9.83e-60 192.0 COG0472@1|root,COG0472@2|Bacteria,1TP8W@1239|Firmicutes,4H9TP@91061|Bacilli,1ZBIK@1386|Bacillus 91061|Bacilli M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan mraY GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.8.13 ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 - R05629,R05630 RC00002,RC02753 ko00000,ko00001,ko01000,ko01011 9.B.146 - - Glycos_transf_4,MraY_sig1 k141_3299_1 1116375.VEJY3_19256 8.12e-227 632.0 COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,1RMR6@1236|Gammaproteobacteria,1XU3G@135623|Vibrionales 135623|Vibrionales Q COG4664 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - - - - - - - - - - DctM k141_3299_2 1116375.VEJY3_19261 4.08e-111 321.0 COG4665@1|root,COG4665@2|Bacteria,1R4Q7@1224|Proteobacteria,1S3JY@1236|Gammaproteobacteria,1XVNA@135623|Vibrionales 135623|Vibrionales Q COG4665 TRAP-type mannitol chloroaromatic compound transport system, small permease component - - - - - - - - - - - - DctQ k141_3299_3 1116375.VEJY3_19266 3.13e-251 690.0 COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,1RRF1@1236|Gammaproteobacteria,1XTQ6@135623|Vibrionales 135623|Vibrionales Q Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - - - - - - - - - - DctP k141_3299_4 1116375.VEJY3_19271 2.6e-298 818.0 COG4564@1|root,COG4564@2|Bacteria,1QTY1@1224|Proteobacteria,1T1XV@1236|Gammaproteobacteria,1XU8A@135623|Vibrionales 135623|Vibrionales T Signal transduction histidine kinase - - 2.7.13.3 ko:K02480 - - - - ko00000,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA_3,sCache_2 k141_34294_1 1116375.VEJY3_23456 3.97e-201 573.0 COG1505@1|root,COG1505@2|Bacteria,1NZ7N@1224|Proteobacteria,1T1KJ@1236|Gammaproteobacteria,1XVJ2@135623|Vibrionales 135623|Vibrionales E Prolyl endopeptidase - - 3.4.21.26 ko:K01322 ko04614,map04614 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S9,Peptidase_S9_N k141_34294_2 1116375.VEJY3_23461 1.04e-213 590.0 COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,1RR7U@1236|Gammaproteobacteria,1XV5Q@135623|Vibrionales 135623|Vibrionales K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_34294_3 1116375.VEJY3_23466 0.0 990.0 COG1620@1|root,COG1620@2|Bacteria,1MV13@1224|Proteobacteria,1RPNW@1236|Gammaproteobacteria,1XSAQ@135623|Vibrionales 135623|Vibrionales C L-lactate permease lldP - - ko:K03303 - - - - ko00000,ko02000 2.A.14 - - Lactate_perm k141_34294_4 1116375.VEJY3_23471 2.12e-274 750.0 COG1304@1|root,COG1304@2|Bacteria,1MUEZ@1224|Proteobacteria,1RPA1@1236|Gammaproteobacteria,1XVR0@135623|Vibrionales 135623|Vibrionales C Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain lldD GO:0003674,GO:0003824,GO:0004457,GO:0004460,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016614,GO:0016898,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.1.2.3 ko:K00101 ko00620,ko01100,map00620,map01100 - R00196 RC00044 ko00000,ko00001,ko01000 - - - FMN_dh k141_11883_1 218284.CCDN010000001_gene753 7.28e-213 588.0 COG1159@1|root,COG1159@2|Bacteria,1TP3R@1239|Firmicutes,4H9WF@91061|Bacilli,1ZCSH@1386|Bacillus 91061|Bacilli S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism era GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113 - ko:K03595 - - - - ko00000,ko03009,ko03029 - - - KH_2,MMR_HSR1 k141_29527_1 96561.Dole_0660 4.37e-40 149.0 COG3039@1|root,COG3039@2|Bacteria,1QQ9Q@1224|Proteobacteria,42S7X@68525|delta/epsilon subdivisions,2WNJ2@28221|Deltaproteobacteria,2MJG4@213118|Desulfobacterales 28221|Deltaproteobacteria L PFAM transposase IS4 family protein - - - - - - - - - - - - DDE_Tnp_1,DUF772 k141_20120_1 1042377.AFPJ01000057_gene4 5.23e-84 254.0 COG2091@1|root,COG2091@2|Bacteria,1R9EK@1224|Proteobacteria,1S0UM@1236|Gammaproteobacteria,46BMD@72275|Alteromonadaceae 1236|Gammaproteobacteria H Belongs to the P-Pant transferase superfamily - - - ko:K06133 ko00770,map00770 - R01625 RC00002 ko00000,ko00001,ko01000 - - - ACPS k141_21074_1 1294265.JCM21738_1820 6.95e-237 660.0 COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HACS@91061|Bacilli,1ZATG@1386|Bacillus 91061|Bacilli IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - 6.2.1.3 ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding,AMP-binding_C k141_16447_1 1379270.AUXF01000006_gene6 1.88e-165 484.0 COG0556@1|root,COG0556@2|Bacteria,1ZSQS@142182|Gemmatimonadetes 142182|Gemmatimonadetes L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage uvrB - - ko:K03702 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - Helicase_C,ResIII,UVR,UvrB k141_37715_3 225849.swp_0941 4.55e-39 137.0 COG1863@1|root,COG1863@2|Bacteria,1MZYJ@1224|Proteobacteria,1S7Z3@1236|Gammaproteobacteria,2QBMS@267890|Shewanellaceae 1236|Gammaproteobacteria P PFAM cation antiporter mnhE - - ko:K05569 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - MNHE k141_17535_2 1294265.JCM21738_1280 1.92e-18 86.3 COG5002@1|root,COG5002@2|Bacteria,1TPPQ@1239|Firmicutes,4HCZW@91061|Bacilli,1ZF21@1386|Bacillus 91061|Bacilli T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - 2.7.13.3 ko:K07642 ko02020,map02020 M00450,M00645,M00646,M00648 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA k141_13020_1 935836.JAEL01000011_gene5155 7.51e-127 390.0 COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,4HAEY@91061|Bacilli,1ZCEM@1386|Bacillus 91061|Bacilli F Belongs to the CarB family carB GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS k141_10528_1 1453501.JELR01000002_gene1444 5.31e-14 70.1 COG0119@1|root,COG0119@2|Bacteria,1MUMX@1224|Proteobacteria,1RMUX@1236|Gammaproteobacteria,4641B@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0119 Isopropylmalate homocitrate citramalate synthases mvaB - 4.1.3.4 ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 M00036,M00088 R01360,R08090 RC00502,RC00503,RC01118,RC01946 ko00000,ko00001,ko00002,ko01000 - - - HMGL-like k141_10528_2 1453501.JELR01000002_gene1445 5.91e-156 457.0 COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,1RM95@1236|Gammaproteobacteria,465G3@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG4770 Acetyl propionyl-CoA carboxylase, alpha subunit mccA - 6.4.1.4 ko:K01968 ko00280,ko01100,map00280,map01100 M00036 R04138 RC00367,RC00942 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2 k141_11884_1 218284.CCDN010000001_gene589 1.79e-58 193.0 COG0457@1|root,COG0457@2|Bacteria,1V7T7@1239|Firmicutes,4HKAH@91061|Bacilli,1ZS6N@1386|Bacillus 91061|Bacilli H Tetratricopeptide repeat ysoA - - - - - - - - - - - TPR_19 k141_17536_1 218284.CCDN010000001_gene1730 2.93e-154 441.0 COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,4HABZ@91061|Bacilli,1ZDK8@1386|Bacillus 91061|Bacilli J tRNA synthetase class II core domain (G, H, P, S and T) thrS GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD k141_24822_1 35841.BT1A1_2826 6.55e-34 128.0 COG2204@1|root,COG4963@1|root,COG2204@2|Bacteria,COG4963@2|Bacteria,1UF2S@1239|Firmicutes,4HDR8@91061|Bacilli,1ZCK7@1386|Bacillus 91061|Bacilli U AAA domain - - - ko:K02282 - - - - ko00000,ko02035,ko02044 - - - AAA_31,Response_reg k141_24822_2 35841.BT1A1_2827 0.000294 45.1 COG3266@1|root,COG3266@2|Bacteria,1V5SZ@1239|Firmicutes,4HHMS@91061|Bacilli,1ZFVC@1386|Bacillus 91061|Bacilli S SAF - - - - - - - - - - - - ChapFlgA,SAF k141_21075_1 109871.XP_006683311.1 1.26e-22 98.6 COG0277@1|root,KOG1231@2759|Eukaryota,3AP0I@33154|Opisthokonta 33154|Opisthokonta C FAD binding domain - - - - - - - - - - - - FAD_binding_4 k141_21075_2 1231057.AMGD01000024_gene2970 3.03e-15 75.1 COG2186@1|root,COG2186@2|Bacteria,1V2TU@1239|Firmicutes,4HDHI@91061|Bacilli,26F4W@186818|Planococcaceae 91061|Bacilli K FCD - - - ko:K05799 - - - - ko00000,ko03000 - - - FCD,GntR k141_29528_1 218284.CCDN010000008_gene4232 4.54e-58 192.0 COG0303@1|root,COG0303@2|Bacteria,1TQJ8@1239|Firmicutes,4HAFT@91061|Bacilli,1ZB4V@1386|Bacillus 91061|Bacilli H molybdopterin moeA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019693,GO:0032324,GO:0034641,GO:0042278,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.10.1.1 ko:K03750 ko00790,ko01100,map00790,map01100 - R09735 RC03462 ko00000,ko00001,ko01000 - - - MoCF_biosynth,MoeA_C,MoeA_N k141_29528_2 218284.CCDN010000008_gene4233 5.73e-103 299.0 COG0314@1|root,COG0314@2|Bacteria,1V3V0@1239|Firmicutes,4HGZD@91061|Bacilli,1ZG9N@1386|Bacillus 91061|Bacilli H COG0314 Molybdopterin converting factor, large subunit moaE GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016782,GO:0016783,GO:0018130,GO:0019538,GO:0019637,GO:0019693,GO:0030366,GO:0032324,GO:0034641,GO:0042278,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.8.1.12 ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09395 RC02507 ko00000,ko00001,ko01000 - - - MoaE k141_29528_3 218284.CCDN010000008_gene4234 1.02e-13 65.1 COG1977@1|root,COG1977@2|Bacteria,1VERN@1239|Firmicutes,4HNP5@91061|Bacilli,1ZIV7@1386|Bacillus 91061|Bacilli H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin moaD - - ko:K03636 ko04122,map04122 - - - ko00000,ko00001 - - - ThiS k141_36434_1 1042377.AFPJ01000019_gene2538 1.42e-209 590.0 COG4242@1|root,COG4242@2|Bacteria,1R5TW@1224|Proteobacteria,1RYMR@1236|Gammaproteobacteria 1236|Gammaproteobacteria PQ Belongs to the peptidase S51 family - - - - - - - - - - - - PPC,Peptidase_S51 k141_36434_2 1042377.AFPJ01000019_gene2537 0.0 1549.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RNBD@1236|Gammaproteobacteria,46642@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec k141_36434_4 1042377.AFPJ01000019_gene2535 1.41e-192 544.0 COG0044@1|root,COG0044@2|Bacteria,1MUPA@1224|Proteobacteria,1RNYU@1236|Gammaproteobacteria,46DC4@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the hydrolytic cleavage of a subset of L- isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation - - - ko:K01305 - - - - ko00000,ko01000,ko01002 - - - Amidohydro_1 k141_36434_5 1283284.AZUK01000001_gene157 1.46e-25 108.0 COG4977@1|root,COG4977@2|Bacteria,1RJSY@1224|Proteobacteria,1S7MM@1236|Gammaproteobacteria,1Y6NB@135624|Aeromonadales 135624|Aeromonadales K helix_turn_helix, arabinose operon control protein - - - ko:K21826 - - - - ko00000,ko03000 - - - DJ-1_PfpI,HTH_18 k141_36434_6 1042377.AFPJ01000019_gene2533 1.92e-171 494.0 COG4242@1|root,COG4242@2|Bacteria,1PR9J@1224|Proteobacteria,1RVJH@1236|Gammaproteobacteria,469D6@72275|Alteromonadaceae 1236|Gammaproteobacteria PQ Peptidase family S51 cphB - 3.4.15.6 ko:K13282 - - R09722 RC00064,RC00141 ko00000,ko01000,ko01002 - - - Peptidase_S51 k141_36434_7 1207075.PputUW4_05373 1.68e-213 604.0 COG1027@1|root,COG1027@2|Bacteria,1R9JY@1224|Proteobacteria,1RP5Z@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Aspartate ammonia-lyase aspA - 4.3.1.1 ko:K01744 ko00250,ko01100,map00250,map01100 - R00490 RC00316,RC02799 ko00000,ko00001,ko01000 - - - FumaraseC_C,Lyase_1 k141_36434_8 1042377.AFPJ01000019_gene2532 1.55e-309 845.0 COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,1RNW9@1236|Gammaproteobacteria,464BR@72275|Alteromonadaceae 1236|Gammaproteobacteria H Aminotransferase class-III spuC - 2.6.1.113 ko:K12256 ko00330,ko01100,map00330,map01100 - R08714 RC00008,RC00062 ko00000,ko00001,ko01000,ko01007 - - iJN746.PP_5182 Aminotran_3 k141_36434_9 1279017.AQYJ01000026_gene216 1.29e-271 749.0 COG0174@1|root,COG0174@2|Bacteria,1MU6V@1224|Proteobacteria,1RPNZ@1236|Gammaproteobacteria,465I0@72275|Alteromonadaceae 1236|Gammaproteobacteria E Glutamine synthetase, catalytic domain - - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C k141_36434_10 1453501.JELR01000001_gene2028 1.38e-67 218.0 COG3047@1|root,COG3047@2|Bacteria 2|Bacteria - - ompW - - ko:K07275 - - - - ko00000 - - - OmpW k141_36434_11 1279017.AQYJ01000026_gene215 1.03e-227 638.0 COG0438@1|root,COG0438@2|Bacteria,1N9EV@1224|Proteobacteria,1RYRV@1236|Gammaproteobacteria,46CMH@72275|Alteromonadaceae 1236|Gammaproteobacteria M Glycosyl transferases group 1 gt4G - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 k141_36434_12 1279017.AQYJ01000026_gene214 1.23e-130 376.0 COG0500@1|root,COG2226@2|Bacteria,1R3QX@1224|Proteobacteria,1RYQ8@1236|Gammaproteobacteria,466WF@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Methionine biosynthesis protein MetW - - - - - - - - - - - - Methyltransf_11,Methyltransf_23 k141_36434_13 1279017.AQYJ01000026_gene213 1.65e-202 568.0 COG3387@1|root,COG3387@2|Bacteria,1NB01@1224|Proteobacteria,1RS3W@1236|Gammaproteobacteria,46581@72275|Alteromonadaceae 1236|Gammaproteobacteria G PFAM Glycoside hydrolase 15-related - - - - - - - - - - - - Prenyltrans k141_7955_161 1357423.S5MQF7_9CAUD 1.93e-22 105.0 4QEHG@10239|Viruses,4QVR3@35237|dsDNA viruses no RNA stage,4QSGQ@28883|Caudovirales,4QIX2@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k141_7955_166 326297.Sama_1922 5.15e-10 67.0 COG2718@1|root,COG2718@2|Bacteria,1MWQM@1224|Proteobacteria,1RQWC@1236|Gammaproteobacteria,2Q9AG@267890|Shewanellaceae 1236|Gammaproteobacteria S Belongs to the UPF0229 family yeaH - - ko:K09786 - - - - ko00000 - - - DUF444 k141_7955_176 1453501.JELR01000001_gene2398 7e-71 218.0 COG2356@1|root,COG2356@2|Bacteria,1RI3H@1224|Proteobacteria,1S6A9@1236|Gammaproteobacteria,4681D@72275|Alteromonadaceae 1236|Gammaproteobacteria L Protein of unknown function (DUF1524) - - - - - - - - - - - - DUF1524 k141_7955_190 34506.g5911 1.6e-37 147.0 COG1875@1|root,2S7WC@2759|Eukaryota,3AIEB@33154|Opisthokonta,3BXHE@33208|Metazoa,3DD55@33213|Bilateria 33208|Metazoa T PhoH-like protein - - - - - - - - - - - - PhoH k141_7955_202 439235.Dalk_1957 5.93e-23 94.7 2DDKV@1|root,32U1R@2|Bacteria,1N5SP@1224|Proteobacteria,431GY@68525|delta/epsilon subdivisions,2WWIM@28221|Deltaproteobacteria 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k141_2496_1 1453501.JELR01000005_gene1778 4e-68 208.0 COG4967@1|root,COG4967@2|Bacteria,1N6TG@1224|Proteobacteria,1SC9Z@1236|Gammaproteobacteria,46937@72275|Alteromonadaceae 1236|Gammaproteobacteria NU COG4967 Tfp pilus assembly protein PilV pilV - - ko:K02671 - - - - ko00000,ko02035,ko02044 - - - N_methyl k141_29805_1 1305836.AXVE01000011_gene722 7.71e-94 290.0 COG1396@1|root,COG1396@2|Bacteria,1TR8B@1239|Firmicutes,4HETZ@91061|Bacilli,26H5B@186818|Planococcaceae 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_3 k141_29805_2 1196029.ALIM01000016_gene4165 1.52e-107 313.0 28H95@1|root,2Z7KY@2|Bacteria,1TQTR@1239|Firmicutes,4HB82@91061|Bacilli,1ZDT7@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF4256) - - - - - - - - - - - - DUF4256 k141_9601_1 218284.CCDN010000001_gene519 3.86e-06 47.4 COG0538@1|root,COG0538@2|Bacteria,1UHPE@1239|Firmicutes,4H9US@91061|Bacilli,1ZBWV@1386|Bacillus 91061|Bacilli C isocitrate icd - 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh k141_26289_1 338963.Pcar_0639 1.98e-53 186.0 COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,42MAP@68525|delta/epsilon subdivisions,2WIYI@28221|Deltaproteobacteria,43SPT@69541|Desulfuromonadales 28221|Deltaproteobacteria P Sodium:sulfate symporter transmembrane region - - - ko:K14445 - - - - ko00000,ko02000 2.A.47.1 - - Na_sulph_symp k141_34584_1 218284.CCDN010000001_gene1334 1.85e-242 675.0 COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HAHB@91061|Bacilli,1ZPZR@1386|Bacillus 91061|Bacilli IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II yngI - - ko:K00666 - - - - ko00000,ko01000,ko01004 - - - AMP-binding,AMP-binding_C k141_36922_1 218284.CCDN010000001_gene700 1.12e-240 676.0 COG0768@1|root,COG0768@2|Bacteria,1TQKI@1239|Firmicutes,4HC5S@91061|Bacilli,1ZBDB@1386|Bacillus 91061|Bacilli M Penicillin-binding Protein pbpI - - ko:K21468 - - - - ko00000,ko01011 - - - PBP_dimer,Transpeptidase k141_10774_1 1116375.VEJY3_06265 1.77e-105 308.0 COG1346@1|root,COG1346@2|Bacteria,1MV81@1224|Proteobacteria,1RS5C@1236|Gammaproteobacteria,1XT9T@135623|Vibrionales 135623|Vibrionales M effector of murein hydrolase yohK - - - - - - - - - - - LrgB k141_10774_2 223926.28806288 6.26e-68 207.0 COG1380@1|root,COG1380@2|Bacteria,1NAY3@1224|Proteobacteria,1SD5V@1236|Gammaproteobacteria,1XXEH@135623|Vibrionales 135623|Vibrionales S effector of murein hydrolase LrgA - - - ko:K06518 - - - - ko00000,ko02000 1.E.14.2 - - LrgA k141_14391_1 1453501.JELR01000002_gene823 4.39e-76 252.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MUWN@1224|Proteobacteria,1RRR7@1236|Gammaproteobacteria,464TZ@72275|Alteromonadaceae 1236|Gammaproteobacteria P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec k141_137_1 983917.RGE_33630 4.09e-12 64.3 2DB77@1|root,2Z7K3@2|Bacteria,1NHMC@1224|Proteobacteria,2VIIN@28216|Betaproteobacteria 28216|Betaproteobacteria S Photosynthetic reaction centre protein - - - ko:K08928 ko02020,map02020 M00597 - - ko00000,ko00001,ko00002,ko00194 - - - Photo_RC k141_137_2 1123267.JONN01000001_gene1495 1.06e-20 83.6 2EI15@1|root,33BSN@2|Bacteria,1N7FB@1224|Proteobacteria,2UFDP@28211|Alphaproteobacteria,2K742@204457|Sphingomonadales 204457|Sphingomonadales C Antenna complex alpha/beta subunit - - - ko:K08926 ko02020,map02020 - - - ko00000,ko00001,ko00194 - - - LHC k141_137_3 1121106.JQKB01000015_gene5771 4.25e-24 93.2 2DPVW@1|root,333MC@2|Bacteria,1N7PY@1224|Proteobacteria,2UHIR@28211|Alphaproteobacteria,2JU4Y@204441|Rhodospirillales 204441|Rhodospirillales C Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers pufB GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K08927 ko02020,map02020 - - - ko00000,ko00001,ko00194 - - - LHC k141_32174_1 1116375.VEJY3_15220 3.39e-204 578.0 COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,1RPQD@1236|Gammaproteobacteria,1XST4@135623|Vibrionales 135623|Vibrionales E COG0006 Xaa-Pro aminopeptidase ampP - 3.4.11.9 ko:K01262 - - - - ko00000,ko01000,ko01002 - - - Creatinase_N,Creatinase_N_2,Peptidase_M24,Peptidase_M24_C k141_8468_1 345219.Bcoa_0570 1.79e-66 215.0 COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,4H9M0@91061|Bacilli,1ZEIA@1386|Bacillus 91061|Bacilli J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family - - 2.1.1.190 ko:K03215 - - - - ko00000,ko01000,ko03009 - - - tRNA_U5-meth_tr k141_16726_1 1121935.AQXX01000127_gene1210 2.18e-304 833.0 COG0174@1|root,COG0174@2|Bacteria,1MU6V@1224|Proteobacteria,1RPNZ@1236|Gammaproteobacteria,1XHHJ@135619|Oceanospirillales 1224|Proteobacteria E Belongs to the glutamine synthetase family glnA1 - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C k141_16726_2 1453501.JELR01000001_gene2777 1.66e-20 89.0 COG0648@1|root,COG0648@2|Bacteria,1R6X2@1224|Proteobacteria,1RSJ8@1236|Gammaproteobacteria,465V6@72275|Alteromonadaceae 1236|Gammaproteobacteria L Domain of unknown function (DUF4862) - - - - - - - - - - - - DUF4862 k141_3684_1 406124.ACPC01000047_gene1811 6.54e-59 207.0 COG1511@1|root,COG1511@2|Bacteria,1TRMJ@1239|Firmicutes,4HB2N@91061|Bacilli,1ZBC1@1386|Bacillus 91061|Bacilli S domain protein - - - - - - - - - - - - - k141_26290_1 1042377.AFPJ01000036_gene1173 1.1e-70 236.0 COG0665@1|root,COG4121@1|root,COG0665@2|Bacteria,COG4121@2|Bacteria,1MZW5@1224|Proteobacteria,1RMTE@1236|Gammaproteobacteria,464VK@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 mnmC GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0004808,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016491,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363 2.1.1.61 ko:K15461 - - R00601,R08702 RC00003,RC00053,RC00060,RC01483 ko00000,ko01000,ko03016 - - - DAO,Methyltransf_30 k141_17978_1 218284.CCDN010000002_gene2660 5.07e-81 244.0 COG1247@1|root,COG1247@2|Bacteria,1V6X5@1239|Firmicutes,4HGYP@91061|Bacilli,1ZQBI@1386|Bacillus 91061|Bacilli M Acetyltransferase (GNAT) domain pat - 2.3.1.183 ko:K03823 ko00440,ko01130,map00440,map01130 - R08871,R08938 RC00004,RC00064 ko00000,ko00001,ko01000 - - - Acetyltransf_1,Acetyltransf_4 k141_14392_2 218284.CCDN010000001_gene692 4.09e-54 171.0 COG0816@1|root,COG0816@2|Bacteria,1V6ER@1239|Firmicutes,4HH04@91061|Bacilli,1ZG6Y@1386|Bacillus 91061|Bacilli L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA yrrK GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - ko:K07447 - - - - ko00000,ko01000 - - - RuvX k141_15589_1 218284.CCDN010000001_gene90 1.66e-153 451.0 COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,4H9VQ@91061|Bacilli,1ZASE@1386|Bacillus 91061|Bacilli M Penicillin-binding Protein pbpX GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - - PASTA,PBP_dimer,Transpeptidase k141_22703_1 1188252.AJYK01000062_gene1925 3.01e-69 224.0 COG2207@1|root,COG2207@2|Bacteria,1MX23@1224|Proteobacteria,1RRXM@1236|Gammaproteobacteria,1Y2JT@135623|Vibrionales 135623|Vibrionales K Arabinose-binding domain of AraC transcription regulator, N-term - - - - - - - - - - - - Arabinose_bd,HTH_18 k141_29806_1 866895.HBHAL_2144 3.88e-18 84.0 COG0115@1|root,COG0115@2|Bacteria,1TPY2@1239|Firmicutes,4HAWW@91061|Bacilli,3NEKD@45667|Halobacillus 91061|Bacilli EH Amino-transferase class IV - - 2.6.1.21 ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 - R01148,R01582,R02459,R02851,R02924,R05053 RC00006,RC00008,RC00025 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_4 k141_34586_1 42565.FP66_15425 7.34e-35 129.0 COG3550@1|root,COG3550@2|Bacteria,1MVAB@1224|Proteobacteria,1RR5N@1236|Gammaproteobacteria 1236|Gammaproteobacteria S protein related to capsule biosynthesis enzymes hipA GO:0000166,GO:0000287,GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0003824,GO:0004672,GO:0004674,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0008144,GO:0008150,GO:0008152,GO:0009279,GO:0009297,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0015267,GO:0015288,GO:0015473,GO:0016020,GO:0016043,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018105,GO:0018193,GO:0018209,GO:0019219,GO:0019222,GO:0019538,GO:0019867,GO:0022607,GO:0022611,GO:0022803,GO:0022829,GO:0022857,GO:0030030,GO:0030031,GO:0030312,GO:0030313,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031975,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0035639,GO:0036094,GO:0036211,GO:0036289,GO:0042710,GO:0043086,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043565,GO:0043711,GO:0044010,GO:0044085,GO:0044092,GO:0044212,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044462,GO:0044464,GO:0044764,GO:0045892,GO:0045934,GO:0046777,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051179,GO:0051234,GO:0051252,GO:0051253,GO:0051704,GO:0055085,GO:0060255,GO:0065007,GO:0065009,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140096,GO:0140110,GO:1901265,GO:1901363,GO:1901564,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 2.7.11.1 ko:K07154 - - - - ko00000,ko01000,ko01001,ko02048 - - - Couple_hipA,HipA_C k141_34586_2 42565.FP66_15420 2.26e-52 165.0 COG1396@1|root,COG1396@2|Bacteria,1N8RD@1224|Proteobacteria,1SC84@1236|Gammaproteobacteria 1236|Gammaproteobacteria K PFAM helix-turn-helix domain protein hipB - - ko:K15773 - - - - ko00000,ko02048,ko03000 - - - HTH_3 k141_25044_1 1294265.JCM21738_4644 9.61e-127 368.0 COG1605@1|root,COG2876@1|root,COG1605@2|Bacteria,COG2876@2|Bacteria,1TP61@1239|Firmicutes,4HB03@91061|Bacilli,1ZB0X@1386|Bacillus 91061|Bacilli E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate aroA - 2.5.1.54,5.4.99.5 ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022,M00024,M00025 R01715,R01826 RC00435,RC03116 ko00000,ko00001,ko00002,ko01000 - - - CM_2,DAHP_synth_1 k141_2497_1 218284.CCDN010000003_gene3012 8.3e-131 375.0 COG0294@1|root,COG0294@2|Bacteria,1TPKT@1239|Firmicutes,4H9SY@91061|Bacilli,1ZAPZ@1386|Bacillus 91061|Bacilli H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives folP GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.15 ko:K00796 ko00790,ko01100,map00790,map01100 M00126,M00841 R03066,R03067 RC00121,RC00842 ko00000,ko00001,ko00002,ko01000 - - - Pterin_bind k141_26291_1 331869.BAL199_04369 2.11e-72 244.0 COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,2TQZU@28211|Alphaproteobacteria,4BPM5@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria F PFAM Carbamoyl-phosphate synthase L chain, ATP binding domain carB - 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS k141_33383_1 218284.CCDN010000002_gene2730 1.29e-117 353.0 COG2213@1|root,COG4668@1|root,COG2213@2|Bacteria,COG4668@2|Bacteria,1TPE3@1239|Firmicutes,4HAVV@91061|Bacilli,1ZC81@1386|Bacillus 91061|Bacilli G COG2213 Phosphotransferase system, mannitol-specific IIBC component mtlA - 2.7.1.197 ko:K02798,ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 M00274 R02704 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1.12,4.A.2.1.2,4.A.2.1.24,4.A.2.1.5 - - PTS_EIIA_2,PTS_EIIC,PTS_IIB k141_4872_1 1294265.JCM21738_1670 3.98e-79 236.0 COG0346@1|root,COG0346@2|Bacteria,1V6KX@1239|Firmicutes,4HJMS@91061|Bacilli,1ZGG2@1386|Bacillus 91061|Bacilli E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily yqjT - - - - - - - - - - - Glyoxalase,Glyoxalase_4 k141_17979_1 1294265.JCM21738_5174 3.51e-96 287.0 COG0346@1|root,COG0346@2|Bacteria,1TP7I@1239|Firmicutes,4H9ND@91061|Bacilli,1ZBUA@1386|Bacillus 91061|Bacilli E COG0346 Lactoylglutathione lyase and related lyases mhqA - - ko:K15975 - - - - ko00000 - - - Glyoxalase k141_36923_1 218284.CCDN010000001_gene361 1.13e-145 413.0 COG1708@1|root,COG1708@2|Bacteria,1VRXD@1239|Firmicutes,4HU5S@91061|Bacilli,1ZQUU@1386|Bacillus 91061|Bacilli S nucleotidyltransferase activity - - - - - - - - - - - - - k141_34587_1 218284.CCDN010000001_gene1008 3.13e-83 253.0 COG1234@1|root,COG1234@2|Bacteria,1TRGP@1239|Firmicutes,4HABM@91061|Bacilli,1ZC3J@1386|Bacillus 91061|Bacilli S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA rnz GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0042802,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 3.1.26.11 ko:K00784 ko03013,map03013 - - - ko00000,ko00001,ko01000,ko03016 - - - Lactamase_B,Lactamase_B_2 k141_31029_1 1294265.JCM21738_2593 4.67e-32 119.0 COG0002@1|root,COG0002@2|Bacteria,1TPVI@1239|Firmicutes,4H9YD@91061|Bacilli,1ZBHP@1386|Bacillus 91061|Bacilli E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde argC GO:0003674,GO:0003824,GO:0003942,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.38 ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R03443 RC00684 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU11190 Semialdhyde_dh,Semialdhyde_dhC k141_31029_2 1294265.JCM21738_2594 3.97e-15 72.0 COG0664@1|root,COG0664@2|Bacteria,1V1AS@1239|Firmicutes,4HF4V@91061|Bacilli,1ZD74@1386|Bacillus 91061|Bacilli K COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - - - - - - - - - - HTH_Crp_2,cNMP_binding k141_9602_1 1294265.JCM21738_3349 3.1e-132 375.0 COG3557@1|root,COG3557@2|Bacteria,1TRX8@1239|Firmicutes,4H9NM@91061|Bacilli,1ZB2J@1386|Bacillus 91061|Bacilli J Belongs to the UPF0374 family ygaC - - ko:K07586 - - - - ko00000 - - - DUF402 k141_9602_2 1294265.JCM21738_3348 7.93e-38 139.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,1ZAY7@1386|Bacillus 91061|Bacilli V ABC transporter ygaD GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702 - ko:K11085 ko02010,map02010 - - - ko00000,ko00001,ko01000,ko02000 3.A.1.106 - - ABC_membrane,ABC_tran k141_21542_1 1116375.VEJY3_17061 5.57e-169 480.0 COG3748@1|root,COG3748@2|Bacteria,1MWHB@1224|Proteobacteria,1RRV4@1236|Gammaproteobacteria,1XUPI@135623|Vibrionales 135623|Vibrionales S Urate oxidase N-terminal - - - - - - - - - - - - Urate_ox_N k141_11973_1 933115.GPDM_00325 1.92e-38 132.0 2E0HT@1|root,32W3J@2|Bacteria,1VC2Y@1239|Firmicutes,4HM2Y@91061|Bacilli,26FZ6@186818|Planococcaceae 91061|Bacilli - - - - - - - - - - - - - - DUF1761 k141_11973_2 1246484.D479_05115 5.39e-83 255.0 COG2207@1|root,COG3449@1|root,COG2207@2|Bacteria,COG3449@2|Bacteria,1TTAX@1239|Firmicutes 1239|Firmicutes K Transcriptional regulator - - - ko:K13652 - - - - ko00000,ko03000 - - - Cass2,GyrI-like,HTH_18,HTH_AraC k141_3686_1 1121090.KB894688_gene1767 5.56e-30 123.0 COG0457@1|root,COG1396@1|root,COG0457@2|Bacteria,COG1396@2|Bacteria,1V0DV@1239|Firmicutes,4HQN4@91061|Bacilli,1ZFEV@1386|Bacillus 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - ko:K20480 ko02024,map02024 - - - ko00000,ko00001,ko03000 - - - HTH_3,TPR_12,TPR_7,TPR_8 k141_139_1 1294265.JCM21738_702 1.23e-64 198.0 COG0265@1|root,COG0265@2|Bacteria,1TSBA@1239|Firmicutes,4HA05@91061|Bacilli,1ZAQG@1386|Bacillus 91061|Bacilli O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain minJ - - - - - - - - - - - PDZ_2 k141_19120_1 378806.STAUR_7974 1.68e-85 263.0 COG1801@1|root,COG1801@2|Bacteria,1N4QE@1224|Proteobacteria,42PDW@68525|delta/epsilon subdivisions,2WK6H@28221|Deltaproteobacteria,2YVUI@29|Myxococcales 28221|Deltaproteobacteria S Protein of unknown function DUF72 - - - - - - - - - - - - DUF72 k141_28666_1 1453501.JELR01000002_gene1019 7.56e-93 280.0 COG0730@1|root,COG0730@2|Bacteria,1MVY3@1224|Proteobacteria,1S21M@1236|Gammaproteobacteria,467A8@72275|Alteromonadaceae 1236|Gammaproteobacteria S Sulfite exporter TauE/SafE - - - ko:K07090 - - - - ko00000 - - - TauE k141_28666_2 1298593.TOL_1517 6.78e-104 307.0 COG1741@1|root,COG1741@2|Bacteria,1MVSW@1224|Proteobacteria,1RNVS@1236|Gammaproteobacteria,1XJQZ@135619|Oceanospirillales 135619|Oceanospirillales S Belongs to the pirin family - - - ko:K06911 - - - - ko00000 - - - Pirin k141_20281_1 218284.CCDN010000005_gene3181 1.45e-108 325.0 COG4473@1|root,COG4473@2|Bacteria,1V1VG@1239|Firmicutes,4HG1K@91061|Bacilli,1ZBQG@1386|Bacillus 91061|Bacilli U ABC transporter ecsB - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - EcsB k141_15591_1 1279017.AQYJ01000023_gene3251 1.97e-121 356.0 COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,1RPGU@1236|Gammaproteobacteria,46519@72275|Alteromonadaceae 1236|Gammaproteobacteria E Threonine dehydratase tdcB - 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - - PALP k141_34589_1 866895.HBHAL_2149 4.5e-49 161.0 COG0262@1|root,COG0262@2|Bacteria,1VAUA@1239|Firmicutes,4HNCF@91061|Bacilli,3NG18@45667|Halobacillus 91061|Bacilli H RibD C-terminal domain - - - - - - - - - - - - RibD_C k141_26293_1 218284.CCDN010000006_gene3603 1.16e-103 313.0 COG0642@1|root,COG2205@2|Bacteria,1V10X@1239|Firmicutes,4HAU7@91061|Bacilli,1ZB6A@1386|Bacillus 91061|Bacilli T Histidine kinase - - - - - - - - - - - - HAMP,HATPase_c,HisKA k141_6069_1 1116375.VEJY3_20801 2.5e-62 199.0 COG3547@1|root,COG3547@2|Bacteria,1NGR7@1224|Proteobacteria,1RMF9@1236|Gammaproteobacteria,1XURY@135623|Vibrionales 135623|Vibrionales L Transposase IS116/IS110/IS902 family - - - - - - - - - - - - DEDD_Tnp_IS110,Transposase_20 k141_6069_4 1219076.N646_3381 1.5e-111 325.0 2DMM3@1|root,32SB6@2|Bacteria,1N0BN@1224|Proteobacteria,1S9U4@1236|Gammaproteobacteria,1XWBE@135623|Vibrionales 135623|Vibrionales S START domain - - - - - - - - - - - - START k141_6069_5 1116375.VEJY3_06545 4.69e-83 248.0 COG0797@1|root,COG0797@2|Bacteria,1MZ8S@1224|Proteobacteria,1S9P2@1236|Gammaproteobacteria,1XX8C@135623|Vibrionales 135623|Vibrionales M Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - ko:K03642 - - - - ko00000 - - - DPBB_1 k141_6069_6 675814.VIC_003298 2.74e-200 560.0 COG2070@1|root,COG2070@2|Bacteria,1MU2F@1224|Proteobacteria,1RQK2@1236|Gammaproteobacteria,1XW4X@135623|Vibrionales 135623|Vibrionales S COG2070 Dioxygenases related to 2-nitropropane dioxygenase - - 1.13.12.16 ko:K00459 ko00910,map00910 - R00025 RC02541,RC02759 ko00000,ko00001,ko01000 - - - NMO k141_6069_7 1116375.VEJY3_20461 1.28e-106 311.0 COG5553@1|root,COG5553@2|Bacteria,1R5RR@1224|Proteobacteria,1S0F8@1236|Gammaproteobacteria 1236|Gammaproteobacteria S cysteine dioxygenase - - - - - - - - - - - - CDO_I k141_6069_8 1116375.VEJY3_20481 9.75e-312 853.0 COG1115@1|root,COG1115@2|Bacteria,1MUI3@1224|Proteobacteria,1RMNF@1236|Gammaproteobacteria,1XZXD@135623|Vibrionales 135623|Vibrionales E Sodium:alanine symporter family - - - ko:K03310 - - - - ko00000 2.A.25 - - Na_Ala_symp k141_6069_9 1219077.VAZ01S_049_00190 3.75e-143 412.0 COG2321@1|root,COG2321@2|Bacteria,1MU4U@1224|Proteobacteria,1RMF8@1236|Gammaproteobacteria,1XTZS@135623|Vibrionales 135623|Vibrionales S Putative neutral zinc metallopeptidase - - - ko:K07054 - - - - ko00000 - - - Zn_peptidase k141_6069_10 1116375.VEJY3_20506 4.83e-310 847.0 COG0277@1|root,COG0277@2|Bacteria,1MUPW@1224|Proteobacteria,1RRDD@1236|Gammaproteobacteria,1XW0M@135623|Vibrionales 135623|Vibrionales C Berberine and berberine like - - - - - - - - - - - - BBE,FAD_binding_4 k141_6069_11 1116375.VEJY3_20516 0.0 1456.0 COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,1RNA5@1236|Gammaproteobacteria,1XSIF@135623|Vibrionales 135623|Vibrionales P Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity katG GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.11.1.21 ko:K03782 ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110 - R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906 RC00034,RC00213,RC00767,RC02141 ko00000,ko00001,ko01000 - - - peroxidase k141_6069_12 1178482.BJB45_14200 4.4e-55 185.0 COG1917@1|root,COG4977@1|root,COG1917@2|Bacteria,COG4977@2|Bacteria,1RKYQ@1224|Proteobacteria,1T290@1236|Gammaproteobacteria,1XRSD@135619|Oceanospirillales 135619|Oceanospirillales K helix_turn_helix, arabinose operon control protein - - - - - - - - - - - - HTH_18 k141_6069_14 1121939.L861_08130 1.15e-90 277.0 COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,1RNQK@1236|Gammaproteobacteria,1XI4M@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline proC - 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 - - - F420_oxidored,P5CR_dimer k141_6069_15 1122207.MUS1_07895 1.14e-08 56.2 COG4663@1|root,COG4663@2|Bacteria,1PCF8@1224|Proteobacteria,1SK0M@1236|Gammaproteobacteria,1XN8V@135619|Oceanospirillales 135619|Oceanospirillales Q Bacterial extracellular solute-binding protein, family 7 - - - - - - - - - - - - DctP k141_6069_16 232346.JHQL01000001_gene2609 1.51e-170 483.0 COG4663@1|root,COG4663@2|Bacteria,1PCF8@1224|Proteobacteria,1SK0M@1236|Gammaproteobacteria,1XN8V@135619|Oceanospirillales 135619|Oceanospirillales Q Bacterial extracellular solute-binding protein, family 7 - - - - - - - - - - - - DctP k141_6069_17 1118153.MOY_13386 3.39e-70 216.0 COG4665@1|root,COG4665@2|Bacteria,1N1S5@1224|Proteobacteria,1SP7P@1236|Gammaproteobacteria,1XPFM@135619|Oceanospirillales 135619|Oceanospirillales Q Tripartite ATP-independent periplasmic transporters, DctQ component - - - - - - - - - - - - DctQ k141_6069_18 1122207.MUS1_07905 1.95e-227 637.0 COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,1RMR6@1236|Gammaproteobacteria,1XNYD@135619|Oceanospirillales 135619|Oceanospirillales Q Tripartite ATP-independent periplasmic transporter, DctM component - - - - - - - - - - - - DctM k141_6069_19 1121943.KB899994_gene1085 3.92e-135 393.0 COG2423@1|root,COG2423@2|Bacteria,1MWH6@1224|Proteobacteria,1RQ3G@1236|Gammaproteobacteria,1XRPM@135619|Oceanospirillales 135619|Oceanospirillales E Ornithine cyclodeaminase/mu-crystallin family - - - - - - - - - - - - OCD_Mu_crystall k141_16748_2 946235.CAER01000060_gene3333 1.97e-05 44.3 2DK9G@1|root,308XT@2|Bacteria,1U44J@1239|Firmicutes,4IDWF@91061|Bacilli,23N9S@182709|Oceanobacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_16748_3 1246484.D479_10021 2.14e-13 69.3 COG1030@1|root,COG1030@2|Bacteria,1V6UR@1239|Firmicutes,4HJIN@91061|Bacilli,3NE52@45667|Halobacillus 91061|Bacilli - - M1-693 - - - - - - - - - - - TspO_MBR k141_171_1 1116375.VEJY3_14830 4.09e-67 215.0 COG1502@1|root,COG1502@2|Bacteria,1MVPU@1224|Proteobacteria,1RN1V@1236|Gammaproteobacteria,1XT62@135623|Vibrionales 135623|Vibrionales I COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes pssA - 2.7.8.8 ko:K00998 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 M00093 R01800 RC00002,RC00017,RC02795 ko00000,ko00001,ko00002,ko01000 - - - PLDc_2,Regulator_TrmB k141_7248_2 240302.BN982_02924 3.22e-21 89.7 COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4H9WY@91061|Bacilli,3NENG@45667|Halobacillus 91061|Bacilli E ATPases associated with a variety of cellular activities tcyC - - ko:K10010 ko02010,map02010 M00234 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3.10,3.A.1.3.14 - iSB619.SA_RS12615 ABC_tran k141_8476_1 1279017.AQYJ01000023_gene3110 1.02e-191 537.0 COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,1RPSV@1236|Gammaproteobacteria,465UN@72275|Alteromonadaceae 1236|Gammaproteobacteria F Belongs to the ATCase OTCase family pyrB GO:0003674,GO:0003824,GO:0004070,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 - - iZ_1308.Z5856 OTCace,OTCace_N k141_8476_2 983545.Glaag_1872 1.96e-253 712.0 COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,464J7@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0405 Gamma-glutamyltransferase ggt - 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept k141_8476_3 1279017.AQYJ01000023_gene3111 8.74e-180 520.0 COG1030@1|root,COG1030@2|Bacteria,1MUJN@1224|Proteobacteria,1RN3U@1236|Gammaproteobacteria,465X3@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG1030 Membrane-bound serine protease (ClpP class) nfeD - - ko:K07403 - - - - ko00000 - - - NfeD k141_8476_5 313612.L8106_23555 7.24e-56 183.0 COG2095@1|root,COG2095@2|Bacteria 2|Bacteria U MarC family integral membrane protein IV02_12955 - - ko:K05595 - - - - ko00000,ko02000 2.A.95.1 - - MarC k141_8476_6 1042377.AFPJ01000014_gene1661 2.13e-307 848.0 COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,1RNIT@1236|Gammaproteobacteria,464TD@72275|Alteromonadaceae 1236|Gammaproteobacteria G Belongs to the GPI family pgi - 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 - - iJN746.PP_1808 PGI k141_8476_7 1279017.AQYJ01000023_gene3115 2.85e-129 380.0 28K8N@1|root,2Z9WC@2|Bacteria,1R5V8@1224|Proteobacteria,1S3I5@1236|Gammaproteobacteria,466GB@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF3549) - - - - - - - - - - - - DUF3549 k141_8476_8 1453501.JELR01000001_gene2956 1.67e-291 803.0 COG1757@1|root,COG1757@2|Bacteria,1MVDF@1224|Proteobacteria,1RS40@1236|Gammaproteobacteria,464WZ@72275|Alteromonadaceae 1236|Gammaproteobacteria C Na H antiporter nhaC - - ko:K03315 - - - - ko00000,ko02000 2.A.35 - - Na_H_antiporter k141_8476_9 1279017.AQYJ01000023_gene3117 1.51e-223 623.0 COG0204@1|root,COG0204@2|Bacteria,1MUFH@1224|Proteobacteria,1RNJQ@1236|Gammaproteobacteria,465A9@72275|Alteromonadaceae 1236|Gammaproteobacteria I Phosphate acyltransferases - - - - - - - - - - - - Acyltransferase k141_8476_10 1279017.AQYJ01000023_gene3118 0.0 1259.0 COG1199@1|root,COG1199@2|Bacteria,1MVCU@1224|Proteobacteria,1RMNX@1236|Gammaproteobacteria,465XA@72275|Alteromonadaceae 1236|Gammaproteobacteria KL COG1199 Rad3-related DNA helicases dinG - 3.6.4.12 ko:K03722 - - - - ko00000,ko01000,ko03400 - - - DEAD,DEAD_2,Helicase_C_2,ResIII k141_8476_11 1042377.AFPJ01000014_gene1656 2.95e-42 141.0 COG3098@1|root,COG3098@2|Bacteria,1N7AG@1224|Proteobacteria,1SCXJ@1236|Gammaproteobacteria,468CS@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria yqcC GO:0008150,GO:0009987,GO:0042710,GO:0044010,GO:0044764,GO:0051704 5.1.3.13 ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R06514 RC01531 ko00000,ko00001,ko00002,ko01000 - - - DUF446 k141_8476_12 1453501.JELR01000001_gene2952 1.15e-88 268.0 COG4067@1|root,COG4067@2|Bacteria,1N7Y2@1224|Proteobacteria,1S91D@1236|Gammaproteobacteria,46CZQ@72275|Alteromonadaceae 1236|Gammaproteobacteria O Putative ATP-dependant zinc protease - - - - - - - - - - - - Zn_protease k141_8476_13 1453501.JELR01000001_gene2951 0.0 897.0 COG1305@1|root,COG1305@2|Bacteria,1MVV3@1224|Proteobacteria,1RRIA@1236|Gammaproteobacteria,465H1@72275|Alteromonadaceae 1236|Gammaproteobacteria E 7 transmembrane helices usually fused to an inactive transglutaminase IV02_00930 - - - - - - - - - - - 7TM_transglut,Transglut_i_TM k141_8476_14 1453501.JELR01000001_gene2950 3.18e-94 283.0 COG0189@1|root,COG0189@2|Bacteria,1MVDU@1224|Proteobacteria,1RR7D@1236|Gammaproteobacteria,464QG@72275|Alteromonadaceae 1236|Gammaproteobacteria HJ COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase) PA1766 - - - - - - - - - - - ATPgrasp_ST k141_19136_2 1042377.AFPJ01000009_gene243 5.21e-19 88.2 COG0845@1|root,COG0845@2|Bacteria,1PEVY@1224|Proteobacteria,1RPEQ@1236|Gammaproteobacteria,466EU@72275|Alteromonadaceae 1236|Gammaproteobacteria M Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - - - - - - - - - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 k141_14411_1 683837.lse_0896 1.61e-17 83.2 COG3594@1|root,COG3594@2|Bacteria,1TPGY@1239|Firmicutes,4HCER@91061|Bacilli,26JF9@186820|Listeriaceae 91061|Bacilli G Acyltransferase family ykrP - - - - - - - - - - - Acyl_transf_3 k141_26306_1 1042377.AFPJ01000043_gene857 5.45e-47 156.0 2DBDT@1|root,2Z8NY@2|Bacteria,1N7S2@1224|Proteobacteria,1RTZE@1236|Gammaproteobacteria,46D1R@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_21567_1 218284.CCDN010000005_gene3229 0.0 913.0 COG1074@1|root,COG1074@2|Bacteria,1TQ35@1239|Firmicutes,4HA64@91061|Bacilli,1ZBG6@1386|Bacillus 91061|Bacilli L ATP-dependent helicase nuclease subunit A addA GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 3.6.4.12 ko:K16898 - - - - ko00000,ko01000,ko03400 - - - PDDEXK_1,UvrD-helicase,UvrD_C k141_16749_3 469383.Cwoe_1900 4.01e-14 70.1 COG1845@1|root,COG1845@2|Bacteria,2GKK8@201174|Actinobacteria,4CSHZ@84995|Rubrobacteria 84995|Rubrobacteria C Cytochrome c oxidase subunit III - - 1.9.3.1 ko:K02276 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.4,3.D.4.6 - - COX3 k141_32315_1 13249.RPRC011158-PA 1e-07 55.1 COG1878@1|root,2SA92@2759|Eukaryota,39KUX@33154|Opisthokonta,3CQUH@33208|Metazoa,3E71F@33213|Bilateria,42CTF@6656|Arthropoda,3T0N2@50557|Insecta,3EDHC@33342|Paraneoptera 33154|Opisthokonta G Putative cyclase - - - - - - - - - - - - Cyclase k141_32315_2 1317122.ATO12_00045 5.3e-116 348.0 COG0624@1|root,COG0624@2|Bacteria,4NI66@976|Bacteroidetes,1HZ8W@117743|Flavobacteriia,2YJ50@290174|Aquimarina 976|Bacteroidetes E Peptidase dimerisation domain - - 3.4.17.11 ko:K01295 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20,Peptidase_M28 k141_34766_2 1116375.VEJY3_16481 1.86e-186 520.0 COG0559@1|root,COG0559@2|Bacteria,1MU25@1224|Proteobacteria,1RNDV@1236|Gammaproteobacteria,1Y19Q@135623|Vibrionales 135623|Vibrionales E Branched-chain amino acid transport system / permease component - - - ko:K01997 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 k141_34766_3 1116375.VEJY3_16476 1.69e-260 716.0 COG0683@1|root,COG0683@2|Bacteria,1MX94@1224|Proteobacteria,1RXJU@1236|Gammaproteobacteria,1XXB3@135623|Vibrionales 135623|Vibrionales E Periplasmic binding protein - - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - DctP,Peripla_BP_6 k141_34766_4 1116375.VEJY3_16471 2.87e-91 267.0 COG3631@1|root,COG3631@2|Bacteria,1RAKK@1224|Proteobacteria,1S508@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Ketosteroid isomerase-related protein - - - - - - - - - - - - SnoaL_2 k141_34766_5 1219076.N646_0931 6.52e-64 199.0 COG1670@1|root,COG1670@2|Bacteria,1RJW7@1224|Proteobacteria,1S7A3@1236|Gammaproteobacteria,1XY3U@135623|Vibrionales 135623|Vibrionales J Acetyltransferase (GNAT) domain - - 2.3.1.128 ko:K03790 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 k141_34766_6 1238450.VIBNISOn1_1390039 3.4e-54 172.0 COG3152@1|root,COG3152@2|Bacteria,1MZJ4@1224|Proteobacteria,1SA1N@1236|Gammaproteobacteria,1XY7E@135623|Vibrionales 135623|Vibrionales S membrane - - - - - - - - - - - - DUF805 k141_34766_7 1116375.VEJY3_16461 7.69e-127 361.0 COG0110@1|root,COG0110@2|Bacteria,1RF1T@1224|Proteobacteria,1S4DA@1236|Gammaproteobacteria,1XTJQ@135623|Vibrionales 135623|Vibrionales S COG0110 Acetyltransferase (isoleucine patch superfamily) lacA - 2.3.1.79 ko:K00661 - - - - ko00000,ko01000 - - - Hexapep,Hexapep_2,Mac k141_34766_8 1280001.BAOA01000053_gene2113 3.64e-84 249.0 COG1765@1|root,COG1765@2|Bacteria,1RCZW@1224|Proteobacteria,1S3XF@1236|Gammaproteobacteria,1XWXE@135623|Vibrionales 135623|Vibrionales O redox protein, regulator of disulfide bond formation yhfA - - ko:K07397 - - - - ko00000 - - - OsmC k141_34766_9 223926.28808345 3.24e-253 697.0 COG0225@1|root,COG0229@1|root,COG0225@2|Bacteria,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,1RNVK@1236|Gammaproteobacteria,1XTSA@135623|Vibrionales 135623|Vibrionales O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine msrA/msrB GO:0003674,GO:0003824,GO:0008113,GO:0008150,GO:0008152,GO:0009405,GO:0016491,GO:0016667,GO:0016671,GO:0044419,GO:0051704,GO:0055114 1.8.4.11,1.8.4.12 ko:K12267 - - - - ko00000,ko01000 - - - PMSR,SelR k141_34766_10 1116375.VEJY3_16441 1.07e-133 382.0 COG1028@1|root,COG1028@2|Bacteria,1RAEZ@1224|Proteobacteria,1S615@1236|Gammaproteobacteria,1XVMC@135623|Vibrionales 135623|Vibrionales IQ C factor cell-cell signaling protein - - - - - - - - - - - - adh_short k141_34766_11 1116375.VEJY3_16436 0.0 939.0 COG3046@1|root,COG3046@2|Bacteria,1MUHX@1224|Proteobacteria,1RNUM@1236|Gammaproteobacteria,1XTNM@135623|Vibrionales 135623|Vibrionales S protein related to deoxyribodipyrimidine photolyase - - - ko:K06876 - - - - ko00000 - - - DPRP k141_34766_12 1116375.VEJY3_16431 3.71e-194 544.0 COG2199@1|root,COG3706@2|Bacteria,1NC00@1224|Proteobacteria,1RR2D@1236|Gammaproteobacteria,1XVMJ@135623|Vibrionales 135623|Vibrionales T COG2199 FOG GGDEF domain - - 2.7.7.65 ko:K13590 ko04112,map04112 - - - ko00000,ko00001,ko01000 - - - GGDEF k141_34766_13 1116375.VEJY3_16426 3.1e-130 370.0 COG2225@1|root,COG2225@2|Bacteria,1MVEV@1224|Proteobacteria,1SFF3@1236|Gammaproteobacteria,1XUAY@135623|Vibrionales 135623|Vibrionales C Malate synthase - - 2.3.3.9 ko:K01638 ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200 M00012 R00472 RC00004,RC00308,RC02747 ko00000,ko00001,ko00002,ko01000 - - - - k141_34766_14 1219076.N646_3636 0.0 1009.0 COG1396@1|root,COG1396@2|Bacteria,1R3Z8@1224|Proteobacteria,1RRMV@1236|Gammaproteobacteria,1XVVD@135623|Vibrionales 135623|Vibrionales K Protein of unknown function (DUF3612) - - - - - - - - - - - - DUF3612,HTH_3,Peptidase_M78 k141_34766_15 1116375.VEJY3_16416 2.07e-221 624.0 COG2199@1|root,COG3452@1|root,COG2199@2|Bacteria,COG3452@2|Bacteria,1R4NG@1224|Proteobacteria,1S0XZ@1236|Gammaproteobacteria,1XU79@135623|Vibrionales 135623|Vibrionales T periplasmic ligand-binding sensor domain - - - - - - - - - - - - CHASE,GGDEF k141_34766_16 1116375.VEJY3_16411 5.06e-124 355.0 COG3145@1|root,COG3145@2|Bacteria,1RGXU@1224|Proteobacteria,1S6DD@1236|Gammaproteobacteria,1XWZP@135623|Vibrionales 135623|Vibrionales L COG3145 Alkylated DNA repair protein - - - - - - - - - - - - 2OG-FeII_Oxy_2 k141_34766_17 1116375.VEJY3_16406 4.19e-207 579.0 29HQP@1|root,304MY@2|Bacteria,1RFYR@1224|Proteobacteria,1S5CC@1236|Gammaproteobacteria,1Y2A9@135623|Vibrionales 135623|Vibrionales S Domain of unknown function (DUF3541) - - - - - - - - - - - - DUF3541 k141_34766_18 1280001.BAOA01000053_gene2127 1.83e-132 377.0 2B0RV@1|root,31T46@2|Bacteria,1QJE8@1224|Proteobacteria,1THDJ@1236|Gammaproteobacteria,1XUC4@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF2913) - - - - - - - - - - - - DUF2913 k141_34766_19 1116375.VEJY3_16391 5.42e-276 757.0 COG0579@1|root,COG0579@2|Bacteria,1N0QB@1224|Proteobacteria,1RN24@1236|Gammaproteobacteria,1XTAP@135623|Vibrionales 135623|Vibrionales S Hydroxyglutarate oxidase - - - ko:K15736 - - - - ko00000,ko01000 - - - DAO k141_34766_20 1116375.VEJY3_16376 9.67e-210 589.0 COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,1S1GD@1236|Gammaproteobacteria,1XUEF@135623|Vibrionales 135623|Vibrionales T diguanylate cyclase - - - - - - - - - - - - GGDEF k141_34766_21 1116375.VEJY3_16371 0.0 1251.0 COG3211@1|root,COG3211@2|Bacteria,1MU8T@1224|Proteobacteria,1RMIU@1236|Gammaproteobacteria,1XSA4@135623|Vibrionales 135623|Vibrionales S Bacterial protein of unknown function (DUF839) - - - ko:K07093 - - - - ko00000 - - - DUF839 k141_34766_22 1116375.VEJY3_16361 3.35e-61 188.0 COG3171@1|root,COG3171@2|Bacteria,1N8GZ@1224|Proteobacteria,1SZV9@1236|Gammaproteobacteria,1XXWD@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria - - - ko:K09923 - - - - ko00000 - - - DUF469 k141_3943_1 218284.CCDN010000001_gene1132 3.76e-119 345.0 COG0289@1|root,COG0289@2|Bacteria,1TR9D@1239|Firmicutes,4HA5X@91061|Bacilli,1ZAWD@1386|Bacillus 91061|Bacilli E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate dapB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R04198,R04199 RC00478 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU22490 DapB_C,DapB_N k141_5048_1 218284.CCDN010000001_gene129 1.84e-106 315.0 COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,1TRC3@1239|Firmicutes,4HADQ@91061|Bacilli,1ZAP8@1386|Bacillus 91061|Bacilli C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) ctaC GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.9.3.1 ko:K02275 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.4,3.D.4.6 - - COX2,COX2_TM,Cytochrom_C,Cytochrome_CBB3 k141_25285_1 218284.CCDN010000002_gene2575 1.14e-67 217.0 2DBIQ@1|root,2Z9GR@2|Bacteria,1USK2@1239|Firmicutes,4HEDG@91061|Bacilli,1ZRBI@1386|Bacillus 91061|Bacilli S Spore germination B3/ GerAC like, C-terminal - - - ko:K06308 - - - - ko00000 - - - Spore_GerAC k141_12286_1 1042377.AFPJ01000025_gene589 0.0 1080.0 COG1505@1|root,COG1505@2|Bacteria,1NZ7N@1224|Proteobacteria,1T1KJ@1236|Gammaproteobacteria,46621@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG1505 Serine proteases of the peptidase family S9A - - 3.4.21.26 ko:K01322 ko04614,map04614 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S9,Peptidase_S9_N k141_1444_1 1385513.N780_13755 1.77e-39 142.0 COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,1TPE2@1239|Firmicutes,4H9WH@91061|Bacilli,2Y9XG@289201|Pontibacillus 91061|Bacilli P Rhodanese Homology Domain - - - - - - - - - - - - Lactamase_B,Rhodanese k141_26633_1 1116375.VEJY3_07495 2.04e-40 135.0 2AXG6@1|root,31PFT@2|Bacteria,1QM5K@1224|Proteobacteria,1TJDF@1236|Gammaproteobacteria,1Y12A@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_13473_1 218284.CCDN010000002_gene2596 3.34e-39 143.0 COG4191@1|root,COG4191@2|Bacteria,1UZ9W@1239|Firmicutes,4HDK2@91061|Bacilli,1ZD85@1386|Bacillus 91061|Bacilli T Histidine kinase kinB - 2.7.13.3 ko:K07697 ko02020,map02020 M00485 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - 5TM-5TMR_LYT,HATPase_c,HisKA k141_422_1 218284.CCDN010000003_gene2974 4.51e-176 499.0 COG3583@1|root,COG3584@1|root,COG3583@2|Bacteria,COG3584@2|Bacteria,1TTIK@1239|Firmicutes,4HC79@91061|Bacilli,1ZC0Q@1386|Bacillus 91061|Bacilli T protein conserved in bacteria yabE - - - - - - - - - - - 3D,DUF348,G5 k141_11008_1 42565.FP66_02695 3.25e-82 244.0 COG0594@1|root,COG0594@2|Bacteria,1MZQE@1224|Proteobacteria,1S90M@1236|Gammaproteobacteria,1XKHZ@135619|Oceanospirillales 135619|Oceanospirillales J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme rnpA - 3.1.26.5 ko:K03536 - - - - ko00000,ko01000,ko03016 - - - Ribonuclease_P k141_22952_1 223926.28809191 2.78e-82 244.0 2AW2H@1|root,31MX9@2|Bacteria,1QJT1@1224|Proteobacteria,1THUA@1236|Gammaproteobacteria,1XXJU@135623|Vibrionales 135623|Vibrionales S Phage protein VPA0889 - - - - - - - - - - - DUF3653 k141_13475_1 84531.JMTZ01000056_gene2535 1.19e-17 82.0 COG1309@1|root,COG1309@2|Bacteria,1R59A@1224|Proteobacteria,1T0P5@1236|Gammaproteobacteria,1XD12@135614|Xanthomonadales 135614|Xanthomonadales K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N k141_2729_2 218284.CCDN010000001_gene1856 2.43e-139 400.0 COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,4HAG5@91061|Bacilli,1ZCUX@1386|Bacillus 91061|Bacilli L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage recA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009292,GO:0009294,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0050896,GO:0051704,GO:0051716,GO:0071496 - ko:K03553 ko03440,map03440 M00729 - - ko00000,ko00001,ko00002,ko03400 - - - RecA k141_22953_1 218284.CCDN010000005_gene3278 2.69e-164 464.0 COG0180@1|root,COG0180@2|Bacteria,1TPY7@1239|Firmicutes,4HA1K@91061|Bacilli,1ZCUY@1386|Bacillus 91061|Bacilli J Tryptophanyl-tRNA synthetase trpS - 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1b k141_26651_2 1042377.AFPJ01000052_gene1548 1.47e-57 187.0 COG3672@1|root,COG3672@2|Bacteria,1RDQS@1224|Proteobacteria,1S3Y1@1236|Gammaproteobacteria,4676R@72275|Alteromonadaceae 1236|Gammaproteobacteria S Bacterial transglutaminase-like cysteine proteinase BTLCP - - - - - - - - - - - - Peptidase_C93 k141_424_1 37919.EP51_20805 1.66e-21 99.8 COG1680@1|root,COG1680@2|Bacteria,2GIX5@201174|Actinobacteria,4FUZ3@85025|Nocardiaceae 201174|Actinobacteria V COG1680 Beta-lactamase class C and other penicillin binding proteins - - 3.4.16.4 ko:K01286 - - - - ko00000,ko01000 - - - Beta-lactamase k141_29959_2 218284.CCDN010000005_gene3398 2.3e-175 490.0 COG1801@1|root,COG1801@2|Bacteria,1TPX4@1239|Firmicutes,4HA0X@91061|Bacilli,1ZATP@1386|Bacillus 91061|Bacilli S Protein of unknown function DUF72 yunF - - - - - - - - - - - DUF72 k141_8650_1 1042377.AFPJ01000025_gene594 1.08e-272 763.0 COG0729@1|root,COG0729@2|Bacteria,1MUKM@1224|Proteobacteria,1RNQ3@1236|Gammaproteobacteria,465KK@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0729 Outer membrane protein ytfM - - ko:K07278 - - - - ko00000,ko02000 1.B.33.2.4 - - Bac_surface_Ag,POTRA,POTRA_TamA_1 k141_8650_2 1279017.AQYJ01000026_gene387 1.28e-141 453.0 COG2911@1|root,COG2911@2|Bacteria,1MUVD@1224|Proteobacteria 1224|Proteobacteria M Protein conserved in bacteria tamB - - ko:K09800 - - - - ko00000,ko02000 - - - TamB k141_19329_2 1279017.AQYJ01000029_gene3393 4e-69 225.0 COG3182@1|root,COG3182@2|Bacteria,1MVET@1224|Proteobacteria,1RY6J@1236|Gammaproteobacteria,465II@72275|Alteromonadaceae 1236|Gammaproteobacteria S PepSY-associated TM region - - - - - - - - - - - - PepSY_TM k141_9825_1 1348635.BBJY01000001_gene2391 3.45e-67 213.0 COG2370@1|root,COG2370@2|Bacteria,1MV6Z@1224|Proteobacteria,1RRHA@1236|Gammaproteobacteria,1XW0Z@135623|Vibrionales 135623|Vibrionales O HupE / UreJ protein - - - - - - - - - - - - HupE_UreJ_2 k141_9825_2 1348635.BBJY01000001_gene2392 3.45e-156 444.0 COG0760@1|root,COG0760@2|Bacteria,1R4ZR@1224|Proteobacteria,1SEDW@1236|Gammaproteobacteria 1236|Gammaproteobacteria O PPIC-type PPIASE domain - - - - - - - - - - - - Rotamase_2 k141_9825_3 1348635.BBJY01000001_gene2393 0.0 1129.0 28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,1RRUM@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF3604) - - - - - - - - - - - - DUF3604 k141_9825_5 1029823.AFIE01000001_gene2103 7.76e-108 325.0 COG3119@1|root,COG3119@2|Bacteria,1MV92@1224|Proteobacteria,1RPDE@1236|Gammaproteobacteria,3NJ0S@468|Moraxellaceae 1236|Gammaproteobacteria P Sulfatase - - 3.1.6.1 ko:K01130 ko00140,ko00600,map00140,map00600 - R03980,R04856 RC00128,RC00231 ko00000,ko00001,ko01000 - - - Sulfatase,Sulfatase_C k141_33600_1 1116375.VEJY3_20416 1.03e-163 485.0 COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,1RMYC@1236|Gammaproteobacteria,1XW5H@135623|Vibrionales 135623|Vibrionales P Cation transporting ATPase, C-terminus - - - - - - - - - - - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase k141_33600_2 1121918.ARWE01000001_gene2709 4.71e-129 374.0 COG2116@1|root,COG2116@2|Bacteria,1MU0W@1224|Proteobacteria,42Q34@68525|delta/epsilon subdivisions,2WN9I@28221|Deltaproteobacteria 28221|Deltaproteobacteria P PFAM formate nitrite transporter fdhC - - ko:K06212,ko:K21993 - - - - ko00000,ko02000 1.A.16.1.1,1.A.16.1.3,1.A.16.2 - - Form_Nir_trans,Response_reg k141_33600_3 1116375.VEJY3_20411 0.0 1301.0 COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,1T1JA@1236|Gammaproteobacteria,1Y37S@135623|Vibrionales 135623|Vibrionales C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - 1.17.1.9 ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001,ko01000 - - - Fer2_4,Fer4,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3 k141_33600_4 1116375.VEJY3_20406 2.12e-40 142.0 COG0479@1|root,COG0479@2|Bacteria,1QVWG@1224|Proteobacteria,1RNMQ@1236|Gammaproteobacteria,1XSXJ@135623|Vibrionales 135623|Vibrionales C 4Fe-4S dicluster domain asrA - - - - - - - - - - - Fer4_22 k141_26653_1 218284.CCDN010000001_gene1540 6.26e-105 311.0 COG1680@1|root,COG1680@2|Bacteria,1TYVU@1239|Firmicutes,4HE5K@91061|Bacilli,1ZCMW@1386|Bacillus 91061|Bacilli V Beta-lactamase - - - - - - - - - - - - Beta-lactamase k141_12321_1 441769.ABFU01000050_gene3950 5.1e-29 114.0 COG1075@1|root,COG1075@2|Bacteria 2|Bacteria KLT acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - - - - - - - - - - Abhydrolase_8,CHAT,PGAP1 k141_11012_1 218284.CCDN010000002_gene2063 1.95e-52 176.0 COG4129@1|root,COG4129@2|Bacteria,1UY2G@1239|Firmicutes,4HAWK@91061|Bacilli,1ZBAR@1386|Bacillus 91061|Bacilli S Aromatic acid exporter family member 1 - - - - - - - - - - - - ArAE_1 k141_22956_1 1042377.AFPJ01000007_gene1845 1.71e-38 133.0 COG3816@1|root,COG3816@2|Bacteria,1RD5Q@1224|Proteobacteria,1S9CC@1236|Gammaproteobacteria,467ZR@72275|Alteromonadaceae 1236|Gammaproteobacteria T protein conserved in bacteria - - - ko:K09986 - - - - ko00000 - - - DUF1285 k141_22956_2 1279017.AQYJ01000025_gene589 2.21e-34 124.0 COG1309@1|root,COG1309@2|Bacteria,1RBU9@1224|Proteobacteria,1S2C2@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator tetR7 - - - - - - - - - - - TetR_N,WHG k141_25298_2 945543.VIBR0546_10109 2.01e-37 126.0 2E588@1|root,3300P@2|Bacteria,1N79I@1224|Proteobacteria,1SCYA@1236|Gammaproteobacteria,1XXZB@135623|Vibrionales 135623|Vibrionales S Domain of unknown function (DUF5062) VVA0683 - - - - - - - - - - - DUF5062 k141_12322_1 240302.BN982_03206 9.83e-28 116.0 COG1196@1|root,COG5412@1|root,COG1196@2|Bacteria,COG5412@2|Bacteria,1TQ28@1239|Firmicutes,4HCMX@91061|Bacilli,3NFV6@45667|Halobacillus 91061|Bacilli D Phage tail tape measure protein, TP901 family - - - - - - - - - - - - PhageMin_Tail k141_37105_1 1294265.JCM21738_3205 1.88e-300 829.0 COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,4H9Y6@91061|Bacilli,1ZBFI@1386|Bacillus 91061|Bacilli L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrB GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.3 ko:K02470 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim k141_37105_2 1294265.JCM21738_3206 7.52e-47 150.0 2E36Q@1|root,32Y6E@2|Bacteria,1VEZV@1239|Firmicutes,4HQTK@91061|Bacilli,1ZIZ5@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF370) yaaB - - - - - - - - - - - DUF370 k141_9826_1 240302.BN982_03596 9.1e-67 219.0 COG4584@1|root,COG4584@2|Bacteria,1TR5X@1239|Firmicutes,4H9QJ@91061|Bacilli 91061|Bacilli L Transposase - - - - - - - - - - - - HTH_23,HTH_38,HTH_7,rve k141_9826_2 240302.BN982_03597 7.22e-162 455.0 COG1484@1|root,COG1484@2|Bacteria,1TRNX@1239|Firmicutes,4HAQR@91061|Bacilli 91061|Bacilli L DNA replication protein - - - - - - - - - - - - IstB_IS21 k141_14566_1 935836.JAEL01000021_gene1469 8.52e-12 64.3 COG0697@1|root,COG0697@2|Bacteria,1TR1G@1239|Firmicutes,4HB57@91061|Bacilli,1ZCN9@1386|Bacillus 91061|Bacilli EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - - - - - - - - - - EamA k141_28889_3 1279017.AQYJ01000023_gene3107 1.29e-124 364.0 COG1091@1|root,COG1091@2|Bacteria,1MUXM@1224|Proteobacteria,1RSNR@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose - - 1.1.1.133 ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777 RC00182 ko00000,ko00001,ko00002,ko01000 - - - RmlD_sub_bind k141_28889_4 1279017.AQYJ01000023_gene3108 0.0 959.0 COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,1RPRC@1236|Gammaproteobacteria,464F2@72275|Alteromonadaceae 1236|Gammaproteobacteria J Arginyl-tRNA synthetase argS GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - iECABU_c1320.ECABU_c21380,iECNA114_1301.ECNA114_1940,iECSE_1348.ECSE_2111,iECSF_1327.ECSF_1736,iEcolC_1368.EcolC_1756,iJN746.PP_5089,iLF82_1304.LF82_0128,iNRG857_1313.NRG857_09405,iUMNK88_1353.UMNK88_2348,ic_1306.c2291 Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d k141_28889_5 1042377.AFPJ01000052_gene1523 5.6e-130 381.0 COG2925@1|root,COG2925@2|Bacteria,1MV0U@1224|Proteobacteria,1RM85@1236|Gammaproteobacteria,464RJ@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG2925 Exonuclease I sbcB GO:0000175,GO:0000287,GO:0000738,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004532,GO:0004536,GO:0004540,GO:0005488,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0008852,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016829,GO:0016835,GO:0016895,GO:0016896,GO:0019439,GO:0034641,GO:0034655,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0046872,GO:0051575,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0140097,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575 3.1.11.1 ko:K01141 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_X-T_C,RNase_T k141_3983_1 1279017.AQYJ01000026_gene280 8.43e-67 206.0 COG4969@1|root,COG4969@2|Bacteria,1N71K@1224|Proteobacteria,1SCYD@1236|Gammaproteobacteria,468QS@72275|Alteromonadaceae 1236|Gammaproteobacteria NU Domain of unknown function (DUF4845) - - - - - - - - - - - - DUF4845 k141_3983_2 1279017.AQYJ01000026_gene281 2.06e-143 409.0 COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,1RMHI@1236|Gammaproteobacteria,464B8@72275|Alteromonadaceae 1236|Gammaproteobacteria U Belongs to the peptidase S26 family lepB GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24,Peptidase_S26 k141_19330_1 218284.CCDN010000002_gene2055 2.42e-172 498.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4H9SC@91061|Bacilli,1ZBEE@1386|Bacillus 91061|Bacilli V ABC transporter malQ - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran k141_20472_1 1279017.AQYJ01000022_gene2683 1.77e-64 218.0 COG2304@1|root,COG2304@2|Bacteria,1MW8K@1224|Proteobacteria,1RNU3@1236|Gammaproteobacteria,46676@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein containing a von Willebrand factor type A (vWA) domain - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - VIT,VWA_3 k141_29960_1 1307436.PBF_10642 2.89e-196 556.0 COG1233@1|root,COG1233@2|Bacteria,1TS4A@1239|Firmicutes,4HB9J@91061|Bacilli,1ZCTK@1386|Bacillus 91061|Bacilli Q COG1233 Phytoene dehydrogenase and related proteins - - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 ko:K10027 ko00906,ko01100,ko01110,map00906,map01100,map01110 - R04787,R04798,R04800,R09691,R09692 RC01214,RC02088,RC02605 ko00000,ko00001,ko01000 - - - Amino_oxidase k141_8654_1 1569209.BBPH01000168_gene405 3.99e-07 53.5 COG0614@1|root,COG0614@2|Bacteria,1RAUP@1224|Proteobacteria,2TUB0@28211|Alphaproteobacteria,2PWC8@265|Paracoccus 28211|Alphaproteobacteria P Periplasmic binding protein - - - ko:K02016 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - Peripla_BP_2 k141_425_5 1195236.CTER_4781 0.000215 45.1 COG1396@1|root,COG1396@2|Bacteria,1UVSQ@1239|Firmicutes,25KMH@186801|Clostridia,3WQXA@541000|Ruminococcaceae 186801|Clostridia K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_3 k141_15803_1 1040983.AXAE01000014_gene4951 1.55e-06 51.2 COG1820@1|root,COG1820@2|Bacteria,1MW8Y@1224|Proteobacteria,2TRBT@28211|Alphaproteobacteria,43HF9@69277|Phyllobacteriaceae 28211|Alphaproteobacteria G Belongs to the metallo-dependent hydrolases superfamily. NagA family nagA GO:0003674,GO:0003824,GO:0005488,GO:0006040,GO:0006044,GO:0006046,GO:0006054,GO:0006082,GO:0008150,GO:0008152,GO:0008270,GO:0008448,GO:0009056,GO:0009987,GO:0016043,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0016999,GO:0017001,GO:0017144,GO:0019213,GO:0019262,GO:0019752,GO:0022607,GO:0042737,GO:0043167,GO:0043169,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046348,GO:0046395,GO:0046872,GO:0046914,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901575 3.5.1.25 ko:K01443 ko00520,ko01130,map00520,map01130 - R02059 RC00166,RC00300 ko00000,ko00001,ko01000 - - - Amidohydro_1 k141_15803_3 1279017.AQYJ01000023_gene3285 4.08e-80 246.0 COG2971@1|root,COG2971@2|Bacteria,1R41I@1224|Proteobacteria,1RPMK@1236|Gammaproteobacteria,466SH@72275|Alteromonadaceae 1236|Gammaproteobacteria G BadF/BadG/BcrA/BcrD ATPase family gspK GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0047931 2.7.1.8 ko:K18676 ko00520,ko01100,map00520,map01100 - R01961 RC00002,RC00017 ko00000,ko00001,ko01000 - - - BcrAD_BadFG k141_22958_1 316055.RPE_2066 4.34e-65 204.0 COG1943@1|root,COG1943@2|Bacteria,1RCWW@1224|Proteobacteria,2U5BB@28211|Alphaproteobacteria,3JY75@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L Transposase IS200 like - - - ko:K07491 - - - - ko00000 - - - Y1_Tnp k141_11015_1 1294265.JCM21738_1400 3.53e-112 325.0 COG1183@1|root,COG1183@2|Bacteria,1TR44@1239|Firmicutes,4HF0K@91061|Bacilli,1ZDC6@1386|Bacillus 91061|Bacilli I Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - 2.7.8.8 ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 M00093 R01800 RC00002,RC00017,RC02795 ko00000,ko00001,ko00002,ko01000 - - - CDP-OH_P_transf k141_21736_1 1453503.AU05_19400 2.02e-09 59.7 COG1721@1|root,COG1721@2|Bacteria,1MXDI@1224|Proteobacteria,1RQSS@1236|Gammaproteobacteria,1YES0@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S Protein of unknown function DUF58 - - - - - - - - - - - - DUF58 k141_33631_2 218284.CCDN010000008_gene4147 1.17e-77 241.0 COG4948@1|root,COG4948@2|Bacteria,1TQMS@1239|Firmicutes,4HBMX@91061|Bacilli,1ZBMS@1386|Bacillus 91061|Bacilli H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) menC GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.2.1.113 ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R04031 RC01053 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU30780 MR_MLE_C,MR_MLE_N k141_14578_1 665959.HMPREF1013_04491 4.46e-51 170.0 COG0412@1|root,COG0412@2|Bacteria,1V78Q@1239|Firmicutes,4HDAM@91061|Bacilli,1ZFXV@1386|Bacillus 91061|Bacilli Q COG0412 Dienelactone hydrolase and related enzymes M1-673 - - - - - - - - - - - DLH k141_13499_1 1279017.AQYJ01000029_gene3799 1.35e-187 524.0 2BVW3@1|root,2Z7TB@2|Bacteria,1MY60@1224|Proteobacteria,1RNI9@1236|Gammaproteobacteria,465TE@72275|Alteromonadaceae 1236|Gammaproteobacteria S 5'-nucleotidase ushA - 3.1.3.5 ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - 5-nucleotidase k141_27756_3 218284.CCDN010000004_gene3153 1.38e-10 61.6 COG0189@1|root,COG0189@2|Bacteria,1V1EV@1239|Firmicutes,4HFNI@91061|Bacilli,1ZBM5@1386|Bacillus 91061|Bacilli HJ YheC/D like ATP-grasp - - - - - - - - - - - - ATPgrasp_YheCD k141_14783_1 1196324.A374_01524 3.05e-10 58.5 COG2963@1|root,COG2963@2|Bacteria,1V6PN@1239|Firmicutes,4HK4K@91061|Bacilli 91061|Bacilli L Transposase and inactivated derivatives - - - ko:K07483,ko:K09936 ko02024,map02024 - - - ko00000,ko00001,ko02000 2.A.7.21 - - HTH_28,Terminase_5 k141_14783_2 1196324.A374_01519 1.71e-168 473.0 COG2801@1|root,COG2801@2|Bacteria,1TQQY@1239|Firmicutes,4HC8M@91061|Bacilli 91061|Bacilli L Transposase and inactivated derivatives - - - ko:K07497 - - - - ko00000 - - - HTH_21,rve,rve_2 k141_726_1 218284.CCDN010000001_gene1859 1.14e-34 126.0 COG1426@1|root,COG1426@2|Bacteria,1V1N7@1239|Firmicutes,4HKW3@91061|Bacilli,1ZDC1@1386|Bacillus 91061|Bacilli S protein conserved in bacteria ymfM - - ko:K15539 - - - - ko00000 - - - DUF4115,HTH_25 k141_29073_1 1294265.JCM21738_2405 4.3e-187 534.0 COG0668@1|root,COG0668@2|Bacteria,1TQXJ@1239|Firmicutes,4HCK2@91061|Bacilli,1ZF3F@1386|Bacillus 91061|Bacilli M Conserved TM helix ygxB - - - - - - - - - - - TM_helix k141_10247_1 498211.CJA_3007 1.63e-149 435.0 COG3507@1|root,COG3507@2|Bacteria,1MWY2@1224|Proteobacteria,1RR93@1236|Gammaproteobacteria,1FI4J@10|Cellvibrio 1236|Gammaproteobacteria G Glycosyl hydrolases family 43 - - 3.2.1.37 ko:K01198 ko00520,ko01100,map00520,map01100 - R01433 RC00467 ko00000,ko00001,ko01000 - GH43 - Glyco_hydro_43 k141_2905_1 1250232.JQNJ01000001_gene1906 5.52e-58 192.0 COG0524@1|root,COG0524@2|Bacteria,4NFH8@976|Bacteroidetes,1HXXT@117743|Flavobacteriia 976|Bacteroidetes G Pfam pfkB family carbohydrate kinase - - 2.7.1.45 ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 M00061,M00308,M00631 R01541 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - PfkB k141_19650_2 1453501.JELR01000002_gene1499 3.47e-73 221.0 COG1017@1|root,COG1017@2|Bacteria,1RI9P@1224|Proteobacteria,1S7H7@1236|Gammaproteobacteria,46B0Z@72275|Alteromonadaceae 1236|Gammaproteobacteria C nitric oxide dioxygenase activity - - - - - - - - - - - - - k141_12664_1 867903.ThesuDRAFT_01667 1.15e-40 148.0 COG0275@1|root,COG0275@2|Bacteria,1TNZV@1239|Firmicutes,248B5@186801|Clostridia,3WCDX@538999|Clostridiales incertae sedis 186801|Clostridia J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA rsmH - 2.1.1.199 ko:K03438 - - - - ko00000,ko01000,ko03009 - - - Methyltransf_5 k141_18525_1 1294265.JCM21738_1639 9.89e-68 213.0 COG0370@1|root,COG0370@2|Bacteria,1TQT3@1239|Firmicutes,4HAIZ@91061|Bacilli,1ZAYP@1386|Bacillus 91061|Bacilli P COG0370 Fe2 transport system protein B yvoD - - - - - - - - - - - Gate k141_5452_1 935836.JAEL01000027_gene2292 9.5e-112 322.0 COG0503@1|root,COG0503@2|Bacteria,1V1BV@1239|Firmicutes,4HFUA@91061|Bacilli,1ZD01@1386|Bacillus 91061|Bacilli F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis apt GO:0003674,GO:0003824,GO:0003999,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006168,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.7 ko:K00759 ko00230,ko01100,map00230,map01100 - R00190,R01229,R04378 RC00063 ko00000,ko00001,ko01000,ko04147 - - - Pribosyltran k141_6572_1 41431.PCC8801_2878 1.32e-95 293.0 COG0462@1|root,COG0462@2|Bacteria,1G00F@1117|Cyanobacteria,3KFSS@43988|Cyanothece 1117|Cyanobacteria F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) - - 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - Pribosyl_synth,Pribosyltran_N k141_6572_2 472759.Nhal_0776 1.81e-76 237.0 COG0412@1|root,COG0412@2|Bacteria,1QVEZ@1224|Proteobacteria,1T2D2@1236|Gammaproteobacteria,1X2R0@135613|Chromatiales 135613|Chromatiales Q Dienelactone hydrolase family - - - - - - - - - - - - DLH k141_6572_3 1502851.FG93_03312 6.63e-60 206.0 COG1926@1|root,COG2312@1|root,COG1926@2|Bacteria,COG2312@2|Bacteria,1MU2S@1224|Proteobacteria,2TWB5@28211|Alphaproteobacteria,3JUQU@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins pcm - 2.1.1.77 ko:K00573 - - - - ko00000,ko01000 - - - Erythro_esteras,PCMT,Pribosyltran k141_36135_1 1294265.JCM21738_372 1.89e-97 289.0 COG0329@1|root,COG0329@2|Bacteria,1TPCK@1239|Firmicutes,4H9K9@91061|Bacilli,1ZBNR@1386|Bacillus 91061|Bacilli E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) dapA - 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS k141_25680_1 1453501.JELR01000001_gene1916 6.68e-73 233.0 COG1354@1|root,COG1354@2|Bacteria,1MVCN@1224|Proteobacteria,1RNBB@1236|Gammaproteobacteria,465A1@72275|Alteromonadaceae 1236|Gammaproteobacteria D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves scpA - - ko:K05896 - - - - ko00000,ko03036 - - - SMC_ScpA k141_20744_1 218284.CCDN010000005_gene3167 1.12e-55 201.0 COG4717@1|root,COG4717@2|Bacteria,1TQP3@1239|Firmicutes,4HBCA@91061|Bacilli,1ZDHB@1386|Bacillus 91061|Bacilli L AAA domain yhaN - - - - - - - - - - - AAA_27 k141_35120_1 42565.FP66_08085 5.06e-120 358.0 COG3012@1|root,COG3012@2|Bacteria,1QCYF@1224|Proteobacteria,1S136@1236|Gammaproteobacteria,1XQUY@135619|Oceanospirillales 135619|Oceanospirillales S Zinc chelation protein SecC - - - - - - - - - - - - SEC-C k141_12665_1 218284.CCDN010000002_gene1984 6.26e-54 180.0 COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,4HACW@91061|Bacilli,1ZC7P@1386|Bacillus 91061|Bacilli F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily purB GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS09895 ADSL_C,Lyase_1 k141_13859_1 218284.CCDN010000005_gene3322 9.45e-95 284.0 COG2358@1|root,COG2358@2|Bacteria,1TPXW@1239|Firmicutes,4HB7U@91061|Bacilli,1ZEBW@1386|Bacillus 91061|Bacilli S NMT1-like family - - - ko:K07080 - - - - ko00000 - - - NMT1_3 k141_21982_1 218284.CCDN010000011_gene4425 2.91e-84 260.0 COG2252@1|root,COG2252@2|Bacteria,1TQC6@1239|Firmicutes,4HANG@91061|Bacilli,1ZARH@1386|Bacillus 91061|Bacilli S permease pbuG - - ko:K06901 - - - - ko00000,ko02000 2.A.1.40 - iYO844.BSU06370 Xan_ur_permease k141_6573_1 674977.VMC_24880 1.2e-34 123.0 COG0663@1|root,COG0663@2|Bacteria,1RD76@1224|Proteobacteria,1RPB6@1236|Gammaproteobacteria,1XU2T@135623|Vibrionales 135623|Vibrionales S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily yrdA - - - - - - - - - - - Hexapep k141_6573_2 223926.28808058 2.25e-39 132.0 2E6QS@1|root,331AY@2|Bacteria,1N7X6@1224|Proteobacteria,1SC8J@1236|Gammaproteobacteria,1XYV9@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF1488) - - - - - - - - - - - - DUF1488 k141_18526_2 1347368.HG964409_gene7255 1.42e-62 196.0 COG0350@1|root,COG0350@2|Bacteria,1VA03@1239|Firmicutes,4HKC0@91061|Bacilli,1ZGW4@1386|Bacillus 91061|Bacilli L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated ogt GO:0003674,GO:0003824,GO:0003908,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 2.1.1.63 ko:K00567 - - - - ko00000,ko01000,ko03400 - - - DNA_binding_1,Methyltransf_1N k141_21983_1 42565.FP66_11080 1.76e-68 212.0 COG1392@1|root,COG1392@2|Bacteria,1MXY9@1224|Proteobacteria,1RQHT@1236|Gammaproteobacteria,1XJD4@135619|Oceanospirillales 135619|Oceanospirillales P COG1392 Phosphate transport regulator (distant homolog of PhoU) - - - ko:K07220 - - - - ko00000 - - - PhoU_div k141_10248_2 1453501.JELR01000002_gene158 1.59e-45 149.0 COG0721@1|root,COG0721@2|Bacteria,1MZQP@1224|Proteobacteria,1S8VY@1236|Gammaproteobacteria,467YW@72275|Alteromonadaceae 1236|Gammaproteobacteria J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatC - 6.3.5.6,6.3.5.7 ko:K02435 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Glu-tRNAGln k141_11411_2 218284.CCDN010000010_gene4366 9.79e-138 390.0 COG0087@1|root,COG0087@2|Bacteria,1TPFT@1239|Firmicutes,4HAEN@91061|Bacilli,1ZCM8@1386|Bacillus 91061|Bacilli J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit rplC GO:0008150,GO:0009893,GO:0010468,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0044087,GO:0044089,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090070,GO:2000232,GO:2000234 - ko:K02906 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L3 k141_11411_3 441769.ABFU01000005_gene2876 5.28e-89 261.0 COG0051@1|root,COG0051@2|Bacteria,1V6C9@1239|Firmicutes,4HIKH@91061|Bacilli,1ZGA6@1386|Bacillus 91061|Bacilli J Involved in the binding of tRNA to the ribosomes rpsJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02946 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S10 k141_29075_1 218284.CCDN010000002_gene2024 2.64e-65 204.0 COG0500@1|root,COG2226@2|Bacteria,1UIWS@1239|Firmicutes,4HIDW@91061|Bacilli,1ZQ1R@1386|Bacillus 91061|Bacilli Q ubiE/COQ5 methyltransferase family - - - - - - - - - - - - Methyltransf_11 k141_26988_1 1279017.AQYJ01000024_gene1015 3.87e-135 389.0 COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,1RNGK@1236|Gammaproteobacteria,466CN@72275|Alteromonadaceae 1236|Gammaproteobacteria J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif prmC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006464,GO:0006479,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0010468,GO:0016043,GO:0016740,GO:0016741,GO:0018364,GO:0019222,GO:0019538,GO:0022411,GO:0032259,GO:0032984,GO:0034641,GO:0034645,GO:0036009,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043414,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.1.1.297 ko:K02493 - - R10806 RC00003,RC03279 ko00000,ko01000,ko03012 - - - MTS,Methyltransf_31 k141_26988_2 1042377.AFPJ01000030_gene480 7.3e-154 439.0 COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,1RMR8@1236|Gammaproteobacteria,4652T@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1230 Co Zn Cd efflux system component - - - ko:K16264 - - - - ko00000,ko02000 2.A.4.1 - - Cation_efflux k141_26988_3 1279017.AQYJ01000024_gene1017 3.33e-33 128.0 COG3608@1|root,COG3608@2|Bacteria,1MUAA@1224|Proteobacteria,1RNQQ@1236|Gammaproteobacteria,464NX@72275|Alteromonadaceae 1236|Gammaproteobacteria S Succinylglutamate desuccinylase / Aspartoacylase family - - - ko:K06987 - - - - ko00000 - - - AstE_AspA k141_20745_1 1121939.L861_18670 2.14e-90 269.0 COG0110@1|root,COG0110@2|Bacteria,1NNC9@1224|Proteobacteria 1224|Proteobacteria S Bacterial transferase hexapeptide (six repeats) - - - - - - - - - - - - Hexapep k141_20745_2 1121939.L861_18665 2.12e-07 51.6 2DNBT@1|root,32WNZ@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k141_25683_1 218284.CCDN010000001_gene538 1.58e-45 155.0 2AZZM@1|root,31S9P@2|Bacteria,1V6WH@1239|Firmicutes,4HMZM@91061|Bacilli,1ZDWA@1386|Bacillus 91061|Bacilli S YtxC-like family ytxC - - - - - - - - - - - YtxC k141_6574_1 1453501.JELR01000002_gene529 1.33e-32 125.0 COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,1RMT7@1236|Gammaproteobacteria,466B9@72275|Alteromonadaceae 1236|Gammaproteobacteria S Bacterial protein of unknown function (DUF885) - - - - - - - - - - - - DUF885 k141_6574_2 511.JT27_13795 3.43e-27 104.0 COG0526@1|root,COG0526@2|Bacteria,1RDJB@1224|Proteobacteria,2VRD0@28216|Betaproteobacteria,3T42T@506|Alcaligenaceae 28216|Betaproteobacteria CO AhpC/TSA family - - - - - - - - - - - - AhpC-TSA k141_26989_1 926554.KI912633_gene3969 1.11e-76 239.0 COG0451@1|root,COG0451@2|Bacteria 2|Bacteria GM ADP-glyceromanno-heptose 6-epimerase activity - - - - - - - - - - - - Epimerase,NAD_binding_10 k141_21984_1 1163409.UUA_12303 1.89e-58 192.0 COG2816@1|root,COG2816@2|Bacteria,1QGCX@1224|Proteobacteria,1RP0Y@1236|Gammaproteobacteria,1X4JM@135614|Xanthomonadales 135614|Xanthomonadales L nadh pyrophosphatase nudC - 3.6.1.22 ko:K03426 ko00760,ko01100,ko04146,map00760,map01100,map04146 - R00103,R03004,R11104 RC00002 ko00000,ko00001,ko01000 - - - NUDIX,NUDIX-like,zf-NADH-PPase k141_2906_1 1232410.KI421414_gene2837 1.71e-56 206.0 COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,42MMA@68525|delta/epsilon subdivisions,2WIZB@28221|Deltaproteobacteria,43S72@69541|Desulfuromonadales 28221|Deltaproteobacteria M Surface antigen bamA - - ko:K07277 - - - - ko00000,ko02000,ko03029 1.B.33 - - Bac_surface_Ag,POTRA k141_36137_1 1294265.JCM21738_585 3.28e-54 184.0 COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,1TQVT@1239|Firmicutes,4HB6K@91061|Bacilli,1ZBS9@1386|Bacillus 91061|Bacilli U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secD GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD_SecF,Sec_GG k141_36137_2 1294265.JCM21738_586 0.000282 40.8 2E6NG@1|root,3318Y@2|Bacteria,1VHES@1239|Firmicutes,4HP4D@91061|Bacilli,1ZJ02@1386|Bacillus 91061|Bacilli S Post-transcriptional regulator yrzD - - - - - - - - - - - Post_transc_reg k141_27760_1 1128398.Curi_c24510 3.34e-08 55.5 COG0517@1|root,COG0517@2|Bacteria,1VA1X@1239|Firmicutes,24MNT@186801|Clostridia 186801|Clostridia EGP PFAM CBS domain - - - - - - - - - - - - CBS k141_27760_2 1191523.MROS_2714 5.72e-27 102.0 COG0105@1|root,COG0105@2|Bacteria 2|Bacteria F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate ndk GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 M00049,M00050,M00052,M00053 R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895 RC00002 ko00000,ko00001,ko00002,ko01000,ko04131 - - - NDK k141_6575_1 765910.MARPU_11295 1.86e-24 106.0 28KC2@1|root,2Z9Z2@2|Bacteria,1RBTZ@1224|Proteobacteria,1SCMS@1236|Gammaproteobacteria,1WZG0@135613|Chromatiales 135613|Chromatiales S CRISPR-associated protein GSU0053 (Cas_GSU0053) - - - ko:K19131 - - - - ko00000,ko02048 - - - Cas_GSU0053 k141_19654_1 953739.SVEN_3904 1.48e-42 159.0 COG0855@1|root,COG0855@2|Bacteria,2GJ0B@201174|Actinobacteria 201174|Actinobacteria P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) ppk - 2.7.4.1 ko:K00937 ko00190,ko03018,map00190,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - PP_kinase,PP_kinase_C,PP_kinase_N k141_29076_1 497964.CfE428DRAFT_0631 6.84e-33 131.0 COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,46TZ3@74201|Verrucomicrobia 74201|Verrucomicrobia T Adenylyl- / guanylyl cyclase, catalytic domain - - - - - - - - - - - - Guanylate_cyc,NB-ARC k141_25702_2 998674.ATTE01000001_gene4593 2.34e-06 50.4 COG1982@1|root,COG1982@2|Bacteria,1MWK4@1224|Proteobacteria,1RMVF@1236|Gammaproteobacteria,460CU@72273|Thiotrichales 72273|Thiotrichales E Orn/Lys/Arg decarboxylase, C-terminal domain cadA - 4.1.1.18,4.1.1.19 ko:K01582,ko:K01584 ko00310,ko00330,ko00960,ko01100,ko01110,map00310,map00330,map00960,map01100,map01110 M00133 R00462,R00566 RC00299 ko00000,ko00001,ko00002,ko01000 - - - OKR_DC_1,OKR_DC_1_C,OKR_DC_1_N k141_19677_2 1453501.JELR01000002_gene685 6.62e-96 283.0 COG0560@1|root,COG0560@2|Bacteria,1RA1A@1224|Proteobacteria,1S21J@1236|Gammaproteobacteria,466GA@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0560 Phosphoserine phosphatase - - - - - - - - - - - - HAD k141_11437_1 218284.CCDN010000007_gene3990 4.09e-157 445.0 COG2801@1|root,COG2801@2|Bacteria,1TQSP@1239|Firmicutes,4HET5@91061|Bacilli,1ZGT4@1386|Bacillus 91061|Bacilli L HTH-like domain - - - ko:K07497 - - - - ko00000 - - - HTH_21,rve,rve_3 k141_8998_1 218284.CCDN010000001_gene1932 2.64e-137 401.0 COG1766@1|root,COG1766@2|Bacteria,1TRK0@1239|Firmicutes,4HBF0@91061|Bacilli,1ZAZN@1386|Bacillus 91061|Bacilli N The M ring may be actively involved in energy transduction fliF - - ko:K02409 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 - - YscJ_FliF,YscJ_FliF_C k141_4211_1 1227360.C176_19684 9.54e-35 123.0 2E305@1|root,32C1V@2|Bacteria,1VEJ9@1239|Firmicutes,4ICP3@91061|Bacilli,26I2Z@186818|Planococcaceae 91061|Bacilli - - - - - - - - - - - - - - - k141_4211_2 1450694.BTS2_0391 6.87e-26 98.2 COG1476@1|root,COG1476@2|Bacteria,1VEGF@1239|Firmicutes,4HNVM@91061|Bacilli,1ZJ56@1386|Bacillus 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - ko:K07729 - - - - ko00000,ko03000 - - - HTH_3 k141_18547_1 42565.FP66_13420 2.24e-104 301.0 COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,1S3Y7@1236|Gammaproteobacteria,1XJNA@135619|Oceanospirillales 135619|Oceanospirillales S Required for maturation of 30S ribosomal subunits rimP - - ko:K09748 - - - - ko00000,ko03009 - - - DUF150,DUF150_C k141_18547_2 42565.FP66_13425 3.46e-106 319.0 COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,1RNQS@1236|Gammaproteobacteria,1XHP7@135619|Oceanospirillales 135619|Oceanospirillales K Participates in both transcription termination and antitermination nusA - - ko:K02600 - - - - ko00000,ko03009,ko03021 - - - HHH_5,KH_5,NusA_N,S1 k141_29088_2 748658.KB907313_gene2072 4.78e-50 161.0 COG1393@1|root,COG1393@2|Bacteria,1MZ4Z@1224|Proteobacteria,1S8XH@1236|Gammaproteobacteria,1X13D@135613|Chromatiales 135613|Chromatiales P Arsenate reductase and related - - 1.20.4.1 ko:K00537 - - - - ko00000,ko01000 - - - ArsC k141_5471_1 1294265.JCM21738_3175 2.04e-76 228.0 COG0207@1|root,COG0207@2|Bacteria,1TSIR@1239|Firmicutes,4H9QS@91061|Bacilli,1ZAUT@1386|Bacillus 91061|Bacilli F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis thyA GO:0003674,GO:0003824,GO:0004799,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0032259,GO:0034641,GO:0034654,GO:0042083,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046385,GO:0046483,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 - - - Thymidylat_synt k141_5471_2 935836.JAEL01000009_gene3795 4.13e-86 256.0 COG0262@1|root,COG0262@2|Bacteria,1VB80@1239|Firmicutes,4HIGJ@91061|Bacilli,1ZG71@1386|Bacillus 91061|Bacilli H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis dfrA - 1.5.1.3 ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 M00126,M00840 R00936,R00937,R00939,R00940,R02235,R02236,R11765 RC00109,RC00110,RC00158 ko00000,ko00001,ko00002,ko01000 - - - DHFR_1 k141_5471_4 1307436.PBF_17549 6.83e-06 47.8 COG0204@1|root,COG0204@2|Bacteria,1UMJA@1239|Firmicutes,4HD2E@91061|Bacilli,1ZEYG@1386|Bacillus 91061|Bacilli I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family ypkP - 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase k141_33918_1 1294265.JCM21738_381 3.4e-40 142.0 COG1744@1|root,COG1744@2|Bacteria,1TPEU@1239|Firmicutes,4HANH@91061|Bacilli,1ZBS3@1386|Bacillus 91061|Bacilli S ABC-type transport system, periplasmic component surface lipoprotein yufN - - ko:K07335 - - - - ko00000 - - - Bmp k141_33918_2 1294265.JCM21738_380 9.42e-47 150.0 COG2188@1|root,COG2188@2|Bacteria,1TQQQ@1239|Firmicutes,4H9TG@91061|Bacilli,1ZB5M@1386|Bacillus 91061|Bacilli K Transcriptional regulator ymfC - - ko:K03710 - - - - ko00000,ko03000 - - - GntR,UTRA k141_2922_1 1453501.JELR01000001_gene1832 3.86e-19 95.9 COG3170@1|root,COG3170@2|Bacteria,1MXV7@1224|Proteobacteria,1RMM5@1236|Gammaproteobacteria,4646P@72275|Alteromonadaceae 1236|Gammaproteobacteria NU COG3170 Tfp pilus assembly protein FimV fimV - - ko:K08086 - - - - ko00000 - - - LysM,TPR_19 k141_11438_1 218284.CCDN010000006_gene3644 5.66e-130 378.0 COG3705@1|root,COG3705@2|Bacteria,1TPZZ@1239|Firmicutes,4HBBA@91061|Bacilli,1ZB4H@1386|Bacillus 91061|Bacilli E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine hisZ - - ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002 - - - tRNA-synt_His k141_24345_2 1279017.AQYJ01000019_gene1491 4.25e-52 164.0 COG0211@1|root,COG0211@2|Bacteria,1MZGH@1224|Proteobacteria,1S8R2@1236|Gammaproteobacteria,467SE@72275|Alteromonadaceae 1236|Gammaproteobacteria J Belongs to the bacterial ribosomal protein bL27 family rpmA GO:0000027,GO:0001558,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040008,GO:0042254,GO:0042255,GO:0042256,GO:0042273,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048518,GO:0050789,GO:0050794,GO:0051128,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 - ko:K02899 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27 k141_24345_3 1279017.AQYJ01000019_gene1490 1.81e-59 184.0 COG0261@1|root,COG0261@2|Bacteria,1MZEW@1224|Proteobacteria,1S5VB@1236|Gammaproteobacteria,467GE@72275|Alteromonadaceae 1236|Gammaproteobacteria J This protein binds to 23S rRNA in the presence of protein L20 rplU GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02888 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L21p k141_24345_5 1453501.JELR01000005_gene1759 7.83e-298 816.0 COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,1RMU8@1236|Gammaproteobacteria,4645I@72275|Alteromonadaceae 1236|Gammaproteobacteria G phosphomannomutase manB - 5.4.2.2,5.4.2.8 ko:K01840,ko:K15778 ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00114 R00959,R01057,R01818,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV k141_18548_1 1033734.CAET01000035_gene3179 1.24e-103 310.0 COG1680@1|root,COG1680@2|Bacteria,1TRR5@1239|Firmicutes,4HAZF@91061|Bacilli,1ZDIA@1386|Bacillus 91061|Bacilli V COG1680 Beta-lactamase class C and other penicillin binding proteins - - - - - - - - - - - - Beta-lactamase k141_5472_1 218284.CCDN010000008_gene4202 1.29e-123 356.0 COG0491@1|root,COG0491@2|Bacteria,1TRED@1239|Firmicutes,4HAP2@91061|Bacilli,1ZAYX@1386|Bacillus 91061|Bacilli S COG0491 Zn-dependent hydrolases, including glyoxylases ytnP - - - - - - - - - - - Lactamase_B k141_36156_1 218284.CCDN010000002_gene2063 4.25e-46 158.0 COG4129@1|root,COG4129@2|Bacteria,1UY2G@1239|Firmicutes,4HAWK@91061|Bacilli,1ZBAR@1386|Bacillus 91061|Bacilli S Aromatic acid exporter family member 1 - - - - - - - - - - - - ArAE_1 k141_11439_1 866895.HBHAL_1687 5.94e-47 162.0 COG0026@1|root,COG0026@2|Bacteria,1TTDR@1239|Firmicutes,4HDHY@91061|Bacilli,3NFV3@45667|Halobacillus 91061|Bacilli F ATP-grasp domain - - - - - - - - - - - - ATP-grasp_4 k141_10266_2 1403313.AXBR01000002_gene4297 2.63e-175 502.0 COG1674@1|root,COG1674@2|Bacteria,1TWB0@1239|Firmicutes,4HCGJ@91061|Bacilli,1ZD0W@1386|Bacillus 91061|Bacilli D FtsK/SpoIIIE family ftsK - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_SpoIIIE k141_10266_5 1196031.ALEG01000039_gene1842 4.99e-14 66.6 COG1476@1|root,COG1476@2|Bacteria,1VK2Z@1239|Firmicutes,4I03X@91061|Bacilli,1ZJZ4@1386|Bacillus 91061|Bacilli K Cro/C1-type HTH DNA-binding domain - - - - - - - - - - - - HTH_3 k141_7664_1 1294265.JCM21738_2593 1.06e-181 510.0 COG0002@1|root,COG0002@2|Bacteria,1TPVI@1239|Firmicutes,4H9YD@91061|Bacilli,1ZBHP@1386|Bacillus 91061|Bacilli E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde argC GO:0003674,GO:0003824,GO:0003942,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.38 ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R03443 RC00684 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU11190 Semialdhyde_dh,Semialdhyde_dhC k141_33919_1 373903.Hore_12210 2.58e-47 172.0 COG0608@1|root,COG0608@2|Bacteria,1TPXE@1239|Firmicutes,247NU@186801|Clostridia,3WB7F@53433|Halanaerobiales 186801|Clostridia L TIGRFAM single-stranded-DNA-specific exonuclease RecJ recJ - - ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1,Helicase_C k141_18549_1 218284.CCDN010000005_gene3268 8.41e-111 344.0 COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HACY@91061|Bacilli,1ZB8K@1386|Bacillus 91061|Bacilli O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE clpB GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564 - ko:K03695 ko04213,map04213 - - - ko00000,ko00001,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N k141_5473_1 1227349.C170_14210 2.38e-49 166.0 COG0241@1|root,COG0241@2|Bacteria,1V6DW@1239|Firmicutes,4HJ23@91061|Bacilli,26XUT@186822|Paenibacillaceae 91061|Bacilli E D,D-heptose 1,7-bisphosphate phosphatase - - - - - - - - - - - - Hydrolase_like k141_1716_2 1283337.B0ZSI0_BPHA1 1.65e-26 100.0 4QD1N@10239|Viruses,4QW5P@35237|dsDNA viruses no RNA stage,4QQ6H@28883|Caudovirales,4QJFA@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k141_1716_3 1283337.B0ZSI1_BPHA1 4.26e-36 129.0 4QBQJ@10239|Viruses,4QVNC@35237|dsDNA viruses no RNA stage,4QPZ3@28883|Caudovirales,4QIN9@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k141_14808_1 218284.CCDN010000008_gene4243 5.45e-120 351.0 COG0123@1|root,COG0123@2|Bacteria,1TQF7@1239|Firmicutes,4HBTF@91061|Bacilli,1ZC2K@1386|Bacillus 91061|Bacilli BQ histone deacetylase acuC - - ko:K04768 - - - - ko00000 - - iYO844.BSU29710 Hist_deacetyl k141_13879_2 218284.CCDN010000001_gene1818 2.32e-93 284.0 COG0167@1|root,COG1146@1|root,COG0167@2|Bacteria,COG1146@2|Bacteria,1TRPI@1239|Firmicutes,4HBRG@91061|Bacilli,1ZD6D@1386|Bacillus 91061|Bacilli CF dihydroorotate dehydrogenase preA - 1.3.1.1 ko:K17723 ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100 M00046 R00977,R01414,R11026 RC00072,RC00123 ko00000,ko00001,ko00002,ko01000 - - - DHO_dh,Fer4_21 k141_20920_1 218284.CCDN010000001_gene734 9.15e-152 442.0 COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,4HA9S@91061|Bacilli,1ZAZ2@1386|Bacillus 91061|Bacilli O Heat shock 70 kDa protein dnaK GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0030246,GO:0030247,GO:0044464,GO:0051704,GO:0098630,GO:0098743,GO:2001065 - ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 - - HSP70 k141_22263_1 935836.JAEL01000147_gene4962 1.56e-110 320.0 COG1435@1|root,COG1435@2|Bacteria,1TRVM@1239|Firmicutes,4HA4A@91061|Bacilli,1ZBMX@1386|Bacillus 91061|Bacilli F thymidine kinase tdk GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R01567,R02099,R08233 RC00002,RC00017 ko00000,ko00001,ko01000 - - iYO844.BSU37060 TK k141_36308_1 574966.KB898647_gene2333 5.3e-28 111.0 COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,1RNGN@1236|Gammaproteobacteria,1XIM1@135619|Oceanospirillales 135619|Oceanospirillales G COG2133 Glucose sorbosone dehydrogenases - - - ko:K21430 - - - - ko00000,ko01000 - - - GSDH k141_36308_2 42565.FP66_10440 3.38e-36 132.0 COG0517@1|root,COG4175@1|root,COG0517@2|Bacteria,COG4175@2|Bacteria,1MU86@1224|Proteobacteria,1RN2R@1236|Gammaproteobacteria,1XHN8@135619|Oceanospirillales 135619|Oceanospirillales E ABC transporter - - 3.6.3.32 ko:K02000 ko02010,map02010 M00208 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.12 - - ABC_tran,CBS k141_32812_2 1453501.JELR01000002_gene1513 2.96e-28 114.0 COG1273@1|root,COG1273@2|Bacteria,1MWCU@1224|Proteobacteria,1RYQ0@1236|Gammaproteobacteria,46705@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF3426) - - - - - - - - - - - - DUF3426,zinc_ribbon_4,zinc_ribbon_5 k141_18866_1 1408473.JHXO01000002_gene3847 7.92e-70 231.0 COG3250@1|root,COG3250@2|Bacteria,4NEDP@976|Bacteroidetes,2G05U@200643|Bacteroidia 976|Bacteroidetes G Glycosyl hydrolase family 2, sugar binding domain protein - - 3.1.1.53 ko:K05970 - - - - ko00000,ko01000 - - - Glyco_hydro_2_N,SASA k141_19890_2 207954.MED92_00685 1.42e-34 120.0 COG0695@1|root,COG0695@2|Bacteria,1N72P@1224|Proteobacteria,1SCA2@1236|Gammaproteobacteria,1XM21@135619|Oceanospirillales 135619|Oceanospirillales O Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins grxC - - ko:K03676 - - - - ko00000,ko03110 - - - Glutaredoxin k141_19890_5 1042377.AFPJ01000038_gene1110 2.13e-152 441.0 COG4942@1|root,COG4942@2|Bacteria,1MY3E@1224|Proteobacteria,1RPQP@1236|Gammaproteobacteria,465VU@72275|Alteromonadaceae 1236|Gammaproteobacteria D COG4942 Membrane-bound metallopeptidase envC GO:0000920,GO:0001896,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008219,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0012501,GO:0016020,GO:0016787,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0042546,GO:0042597,GO:0043085,GO:0044085,GO:0044093,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071554,GO:0071840,GO:0071944 - - - - - - - - - - Peptidase_M23 k141_27935_1 207954.MED92_07811 2.01e-23 95.9 COG2116@1|root,COG2116@2|Bacteria,1MU0W@1224|Proteobacteria,1RQ6K@1236|Gammaproteobacteria,1XHKY@135619|Oceanospirillales 135619|Oceanospirillales P Formate/nitrite transporter - - - - - - - - - - - - Form_Nir_trans k141_27935_2 1116375.VEJY3_23021 6.5e-45 155.0 COG1448@1|root,COG1448@2|Bacteria,1MUT0@1224|Proteobacteria,1RN02@1236|Gammaproteobacteria,1Y01E@135623|Vibrionales 135623|Vibrionales E Aminotransferase class I and II - - 2.6.1.57 ko:K00832 ko00270,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 M00024,M00025,M00034,M00040 R00694,R00734,R01731,R07396,R10845 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k141_6852_1 1294265.JCM21738_1204 2.56e-110 345.0 COG0553@1|root,COG4715@1|root,COG0553@2|Bacteria,COG4715@2|Bacteria,1TPFZ@1239|Firmicutes,4HAIF@91061|Bacilli,1ZBZT@1386|Bacillus 91061|Bacilli L COG0553 Superfamily II DNA RNA helicases, SNF2 family snf - - - - - - - - - - - Helicase_C,SNF2_N,SNF2_assoc,SWIM k141_35383_1 1042377.AFPJ01000020_gene2038 8.38e-42 146.0 COG0406@1|root,COG0406@2|Bacteria,1MYD7@1224|Proteobacteria,1SDUT@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Phosphoglycerate mutase family - - - - - - - - - - - - His_Phos_1 k141_35383_2 1207076.ALAT01000099_gene2443 3.14e-235 679.0 COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,1RMA7@1236|Gammaproteobacteria,1Z15U@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria E Aminopeptidase N pepN GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0009056,GO:0009987,GO:0016020,GO:0016787,GO:0019538,GO:0033218,GO:0034641,GO:0042277,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - iECIAI1_1343.ECIAI1_0973,iECO103_1326.ECO103_0977,iECP_1309.ECP_0944,iECSE_1348.ECSE_0993,iECW_1372.ECW_m1042,iEKO11_1354.EKO11_2898,iWFL_1372.ECW_m1042 DUF3458,DUF3458_C,Peptidase_M1 k141_14178_1 223926.28807822 2.82e-253 698.0 COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,1RNEW@1236|Gammaproteobacteria,1XU7G@135623|Vibrionales 135623|Vibrionales F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP purA GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 - - - Adenylsucc_synt k141_14178_2 575788.VS_0274 3.51e-30 107.0 COG3242@1|root,COG3242@2|Bacteria,1N6V7@1224|Proteobacteria,1SCHT@1236|Gammaproteobacteria,1XZ34@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria C5260 - - ko:K09937 - - - - ko00000 - - - DUF2065 k141_14178_3 1219076.N646_1903 1.03e-190 534.0 COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,1RM8Z@1236|Gammaproteobacteria,1XTY8@135623|Vibrionales 135623|Vibrionales O HflC and HflK could regulate a protease hflC GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564 - ko:K04087 - M00742 - - ko00000,ko00002,ko01000 - - - Band_7 k141_14178_4 1116375.VEJY3_14345 5.02e-247 683.0 COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,1RMUG@1236|Gammaproteobacteria,1XU48@135623|Vibrionales 135623|Vibrionales O HflC and HflK could encode or regulate a protease hflK GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564 - ko:K04088 - M00742 - - ko00000,ko00002,ko01000 - - - Band_7,HflK_N k141_14178_5 1116375.VEJY3_14350 9.16e-301 821.0 COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,1RN7V@1236|Gammaproteobacteria,1XUG9@135623|Vibrionales 135623|Vibrionales S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis hflX - - ko:K03665 - - - - ko00000,ko03009 - - - GTP-bdg_M,GTP-bdg_N,MMR_HSR1 k141_14178_6 1116375.VEJY3_14355 2.52e-54 170.0 COG1923@1|root,COG1923@2|Bacteria,1MZM1@1224|Proteobacteria,1S8W0@1236|Gammaproteobacteria,1XXVV@135623|Vibrionales 135623|Vibrionales J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs hfq GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010608,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016246,GO:0016441,GO:0016458,GO:0019222,GO:0022607,GO:0022613,GO:0022618,GO:0030423,GO:0031047,GO:0031123,GO:0031124,GO:0034622,GO:0034641,GO:0035194,GO:0040029,GO:0043170,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0048519,GO:0050789,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 - - - ko00000,ko00001,ko03019,ko03036 - - - Hfq k141_14178_7 223926.28807828 4.4e-216 597.0 COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,1RMDU@1236|Gammaproteobacteria,1XSXN@135623|Vibrionales 135623|Vibrionales F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) miaA GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 - R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 - - - IPPT k141_14178_8 1116375.VEJY3_14365 1.38e-298 829.0 COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,1RM89@1236|Gammaproteobacteria,1XTP3@135623|Vibrionales 135623|Vibrionales L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex mutL GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K03572 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - DNA_mis_repair,HATPase_c_3,MutL_C k141_920_1 550540.Fbal_3017 0.0 936.0 COG0610@1|root,COG0610@2|Bacteria,1QX4Z@1224|Proteobacteria,1T4Q5@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Z1 domain - - - - - - - - - - - - Z1 k141_7921_1 634956.Geoth_2955 4.37e-24 99.0 COG1175@1|root,COG1175@2|Bacteria,1TREE@1239|Firmicutes,4H9PV@91061|Bacilli,1WG7J@129337|Geobacillus 91061|Bacilli P Binding-protein-dependent transport system inner membrane component - - - ko:K02025 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - BPD_transp_1 k141_7921_2 265729.GS18_0213110 1.17e-81 253.0 COG1653@1|root,COG1653@2|Bacteria,1TRIH@1239|Firmicutes,4HBRS@91061|Bacilli,1ZEWW@1386|Bacillus 91061|Bacilli G Bacterial extracellular solute-binding protein - - - ko:K02027 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - SBP_bac_1,SBP_bac_8 k141_18867_1 218284.CCDN010000001_gene742 3.42e-83 248.0 COG1610@1|root,COG1610@2|Bacteria,1V6F2@1239|Firmicutes,4HIQP@91061|Bacilli,1ZGGX@1386|Bacillus 91061|Bacilli S Yqey-like protein yqeY - - ko:K09117 - - - - ko00000 - - - YqeY k141_18867_2 985762.SAGN_02995 3.71e-25 94.4 COG0828@1|root,COG0828@2|Bacteria,1VEHU@1239|Firmicutes,4HNPV@91061|Bacilli,4GZXG@90964|Staphylococcaceae 91061|Bacilli J Belongs to the bacterial ribosomal protein bS21 family rpsU GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - ko:K02970 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S21 k141_27279_1 218284.CCDN010000007_gene3954 5.3e-119 358.0 COG0247@1|root,COG2181@1|root,COG0247@2|Bacteria,COG2181@2|Bacteria,1TPG1@1239|Firmicutes,4HB2J@91061|Bacilli,1ZBAJ@1386|Bacillus 91061|Bacilli C COG0247 Fe-S oxidoreductase ywjF - - - - - - - - - - - CCG,Fer4_8 k141_25924_1 485916.Dtox_2929 4.86e-16 80.9 COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,25100@186801|Clostridia,260TC@186807|Peptococcaceae 186801|Clostridia M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein murF - 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 - R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M k141_25924_2 880072.Desac_0601 2.67e-25 111.0 COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,42MXF@68525|delta/epsilon subdivisions,2WIJZ@28221|Deltaproteobacteria,2MQDM@213462|Syntrophobacterales 28221|Deltaproteobacteria M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein murF - 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 - R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M k141_6853_1 1307436.PBF_00985 2.04e-97 289.0 COG1136@1|root,COG1136@2|Bacteria,1TP5M@1239|Firmicutes,4HD2M@91061|Bacilli,1ZPYV@1386|Bacillus 91061|Bacilli P ABC transporter yclH - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_6853_2 1305836.AXVE01000011_gene1132 1.75e-20 92.8 COG0577@1|root,COG0577@2|Bacteria,1TPSE@1239|Firmicutes,4HCAX@91061|Bacilli,26F15@186818|Planococcaceae 91061|Bacilli V FtsX-like permease family yclI GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD k141_31500_1 1453501.JELR01000001_gene2296 4.61e-120 355.0 COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,1RN93@1236|Gammaproteobacteria,464G4@72275|Alteromonadaceae 1236|Gammaproteobacteria F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily purB - 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 - - - ASL_C,Lyase_1 k141_36309_1 1071073.KI530537_gene1453 4.87e-44 155.0 2A3QE@1|root,30S81@2|Bacteria,1V4TY@1239|Firmicutes,4HHXW@91061|Bacilli,1ZG86@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_24638_1 338969.Rfer_1603 1.3e-88 266.0 COG1595@1|root,COG1595@2|Bacteria,1RHKM@1224|Proteobacteria,2VRMP@28216|Betaproteobacteria,4AHN8@80864|Comamonadaceae 28216|Betaproteobacteria K Sigma-70 region 2 - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_3126_1 42565.FP66_07530 3.67e-166 474.0 COG2067@1|root,COG2067@2|Bacteria,1MUU4@1224|Proteobacteria,1RQZJ@1236|Gammaproteobacteria,1XJ8A@135619|Oceanospirillales 135619|Oceanospirillales I Long-chain fatty acid transport protein fadL - - ko:K06076 - - - - ko00000,ko02000 1.B.9 - - Toluene_X k141_19891_1 1408303.JNJJ01000043_gene3498 4.61e-94 294.0 COG3291@1|root,COG3291@2|Bacteria,1V0FC@1239|Firmicutes,4HES3@91061|Bacilli,1ZE9N@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF1906) - - - - - - - - - - - - DUF1906 k141_9281_1 223926.28808106 0.0 1190.0 COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,1RMM1@1236|Gammaproteobacteria,1XT9G@135623|Vibrionales 135623|Vibrionales D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 gidA GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - ko:K03495 - - R08701 RC00053,RC00209,RC00870 ko00000,ko03016,ko03036 - - - GIDA,GIDA_assoc k141_4339_1 1121936.AUHI01000006_gene1931 1.88e-27 110.0 COG1906@1|root,COG1906@2|Bacteria,1UHZ1@1239|Firmicutes,4ISFQ@91061|Bacilli 91061|Bacilli S membrane - - - - - - - - - - - - - k141_4339_2 913865.DOT_1981 1.72e-18 82.0 COG5621@1|root,COG5621@2|Bacteria 2|Bacteria S spheroidene biosynthetic process attH - - - - - - - - - - - CrtC,Lipocalin_9 k141_22268_1 316067.Geob_1823 2.43e-19 92.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WJ88@28221|Deltaproteobacteria,43TKB@69541|Desulfuromonadales 28221|Deltaproteobacteria T response regulator ntrX - - ko:K13599 ko02020,map02020 M00498 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat k141_30326_1 1279017.AQYJ01000026_gene324 2.05e-96 284.0 COG0806@1|root,COG0806@2|Bacteria,1MWQR@1224|Proteobacteria,1RNJ2@1236|Gammaproteobacteria,467CY@72275|Alteromonadaceae 1236|Gammaproteobacteria J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes rimM GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 - ko:K02860 - - - - ko00000,ko03009 - - - PRC,RimM k141_27281_1 1294265.JCM21738_3359 4.94e-52 164.0 2CEK7@1|root,330II@2|Bacteria,1VFTN@1239|Firmicutes,4HNJY@91061|Bacilli,1ZI0N@1386|Bacillus 91061|Bacilli S WVELL protein yfhJ - - - - - - - - - - - WVELL k141_27281_2 1294265.JCM21738_3360 2.69e-35 121.0 2ERTV@1|root,33JD2@2|Bacteria,1VG3A@1239|Firmicutes,4HPKX@91061|Bacilli,1ZIVJ@1386|Bacillus 91061|Bacilli S reproduction sspK - - ko:K06428 - - - - ko00000 - - - SspK k141_7922_1 223926.28807400 8.7e-123 357.0 COG1609@1|root,COG1609@2|Bacteria,1N8ZA@1224|Proteobacteria,1RSGV@1236|Gammaproteobacteria,1XSKZ@135623|Vibrionales 135623|Vibrionales K COG1609 Transcriptional regulators ebgR - - ko:K12113 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 k141_36336_1 1117647.M5M_07615 3.34e-167 501.0 COG1629@1|root,COG1629@2|Bacteria,1MVSG@1224|Proteobacteria,1RS33@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Carboxypeptidase regulatory-like domain - - - - - - - - - - - - CarboxypepD_reg k141_959_1 1128912.GMES_4577 2.02e-05 46.6 COG0596@1|root,COG0596@2|Bacteria,1QUBR@1224|Proteobacteria,1RSF9@1236|Gammaproteobacteria,466FR@72275|Alteromonadaceae 1236|Gammaproteobacteria S The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters bioH GO:0003674,GO:0003824,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016787,GO:0016788,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0052689,GO:0071704,GO:0072330,GO:0090499,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.1.1.85 ko:K02170 ko00780,ko01100,map00780,map01100 M00572 R09725 RC00460,RC00461 ko00000,ko00001,ko00002,ko01000 - - iBWG_1329.BWG_3103,iECBD_1354.ECBD_0333,iECDH10B_1368.ECDH10B_3587,iECDH1ME8569_1439.ECDH1ME8569_3291,iETEC_1333.ETEC_3662,iEcDH1_1363.EcDH1_0301,iJO1366.b3412,iY75_1357.Y75_RS20155 Abhydrolase_1,Abhydrolase_6 k141_959_2 1279017.AQYJ01000020_gene1299 2.58e-187 532.0 COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,1RNS6@1236|Gammaproteobacteria,4655Y@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide bioF GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.47 ko:K00652 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R03210,R10124 RC00004,RC00039,RC02725 ko00000,ko00001,ko00002,ko01000,ko01007 - - iEC55989_1330.EC55989_0819,iECO111_1330.ECO111_0837,iECO26_1355.ECO26_0902,iSDY_1059.SDY_0830 Aminotran_1_2 k141_29331_1 221109.22776413 5.37e-85 273.0 COG1404@1|root,COG1404@2|Bacteria,1TPH1@1239|Firmicutes,4HBQH@91061|Bacilli,23IZR@182709|Oceanobacillus 91061|Bacilli O PA domain prtS - 3.4.21.110,3.4.21.96 ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 - - - ko00000,ko00001,ko01000,ko01002,ko03110 - - - FIVAR,Gram_pos_anchor,Inhibitor_I9,PA,Peptidase_S8,SLH,YSIRK_signal,fn3_5 k141_18923_1 218284.CCDN010000002_gene2128 3.13e-83 255.0 COG0083@1|root,COG0083@2|Bacteria,1TRWS@1239|Firmicutes,4HCQN@91061|Bacilli,1ZBK1@1386|Bacillus 91061|Bacilli E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate thrB GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.39 ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 M00018 R01771 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N k141_34145_3 1116375.VEJY3_12545 0.0 896.0 COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,1RPNE@1236|Gammaproteobacteria,1XTZV@135623|Vibrionales 135623|Vibrionales I COG1022 Long-chain acyl-CoA synthetases (AMP-forming) - - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding k141_6888_1 1042377.AFPJ01000024_gene803 2.9e-144 426.0 COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,1RQR7@1236|Gammaproteobacteria,4668G@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria ycbB GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0006508,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0008236,GO:0008238,GO:0009273,GO:0009987,GO:0016740,GO:0016746,GO:0016755,GO:0016787,GO:0016807,GO:0017171,GO:0019538,GO:0033554,GO:0042546,GO:0043164,GO:0043170,GO:0044036,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0050896,GO:0051716,GO:0070004,GO:0070008,GO:0070011,GO:0071554,GO:0071704,GO:0071840,GO:0071972,GO:0140096,GO:1901564 - ko:K21470 - - - - ko00000,ko01002,ko01011 - - - PG_binding_1,YkuD k141_16272_2 218284.CCDN010000002_gene2063 3.11e-56 186.0 COG4129@1|root,COG4129@2|Bacteria,1UY2G@1239|Firmicutes,4HAWK@91061|Bacilli,1ZBAR@1386|Bacillus 91061|Bacilli S Aromatic acid exporter family member 1 - - - - - - - - - - - - ArAE_1 k141_4365_1 1116375.VEJY3_18141 3.79e-37 132.0 COG2207@1|root,COG2207@2|Bacteria,1MXDJ@1224|Proteobacteria,1RNJM@1236|Gammaproteobacteria,1XY6U@135623|Vibrionales 135623|Vibrionales K helix_turn_helix, arabinose operon control protein - - - ko:K02508,ko:K18954 - - - - ko00000,ko03000 - - - AraC_binding,HTH_18 k141_4365_2 1116375.VEJY3_18136 1.37e-288 788.0 COG0654@1|root,COG0654@2|Bacteria,1MV8T@1224|Proteobacteria,1RMD7@1236|Gammaproteobacteria 1236|Gammaproteobacteria CH Catalyzes the formation of protocatechuate from 4-hydroxybenzoate pobA - 1.14.13.127,1.14.13.2 ko:K00481,ko:K05712 ko00360,ko00362,ko01100,ko01120,ko01220,map00360,map00362,map01100,map01120,map01220 M00545 R01298,R06786,R06787 RC00046,RC00236 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_3 k141_23651_1 218284.CCDN010000008_gene4133 7.47e-263 730.0 COG0296@1|root,COG0296@2|Bacteria,1TP4M@1239|Firmicutes,4HAPM@91061|Bacilli,1ZCHU@1386|Bacillus 91061|Bacilli G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position glgB GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901576 2.4.1.18 ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02110 - ko00000,ko00001,ko00002,ko01000,ko04147 - CBM48,GH13 - Alpha-amylase,Alpha-amylase_C,CBM_48 k141_18924_1 218284.CCDN010000001_gene228 9.37e-77 239.0 COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,4HA7K@91061|Bacilli,1ZDDX@1386|Bacillus 91061|Bacilli F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction ackA - 2.7.2.1 ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00315,R01353 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - Acetate_kinase k141_30336_1 1116375.VEJY3_07060 1.54e-52 179.0 COG1292@1|root,COG1292@2|Bacteria,1MV0K@1224|Proteobacteria,1RP3E@1236|Gammaproteobacteria,1XTJH@135623|Vibrionales 135623|Vibrionales M Belongs to the BCCT transporter (TC 2.A.15) family - - - ko:K03451 - - - - ko00000 2.A.15 - - BCCT k141_30336_2 1116375.VEJY3_07065 1.38e-73 222.0 COG0645@1|root,COG0645@2|Bacteria,1N1S8@1224|Proteobacteria,1SEDC@1236|Gammaproteobacteria,1XXSN@135623|Vibrionales 135623|Vibrionales S AAA domain - - - - - - - - - - - - AAA_33 k141_30336_4 1116375.VEJY3_08050 1.14e-71 217.0 2AWCY@1|root,31N8T@2|Bacteria,1QK03@1224|Proteobacteria,1TI2H@1236|Gammaproteobacteria,1XY86@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_30336_5 1116375.VEJY3_08040 2.68e-276 763.0 COG0642@1|root,COG2205@2|Bacteria,1N1Z2@1224|Proteobacteria,1RPG9@1236|Gammaproteobacteria,1XV7G@135623|Vibrionales 135623|Vibrionales T His Kinase A (phosphoacceptor) domain - - 2.7.13.3 ko:K07645 ko02020,ko02024,map02020,map02024 M00453 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - 2CSK_N,HATPase_c,HisKA k141_30336_6 1116375.VEJY3_08035 4.45e-143 405.0 COG0745@1|root,COG0745@2|Bacteria,1N0YI@1224|Proteobacteria,1RPNH@1236|Gammaproteobacteria,1Y2IA@135623|Vibrionales 135623|Vibrionales K Transcriptional regulatory protein, C terminal - - - ko:K07666 ko02020,ko02024,map02020,map02024 M00453 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C k141_30336_7 1116375.VEJY3_08030 1.22e-134 383.0 COG3063@1|root,COG3063@2|Bacteria,1RD9T@1224|Proteobacteria,1S3R3@1236|Gammaproteobacteria,1XX1A@135623|Vibrionales 135623|Vibrionales NU COG0457 FOG TPR repeat - - - - - - - - - - - - TPR_19,TPR_8 k141_30336_8 1116375.VEJY3_08025 2.34e-156 442.0 COG0300@1|root,COG0300@2|Bacteria,1RAFB@1224|Proteobacteria,1S2HE@1236|Gammaproteobacteria,1XVH5@135623|Vibrionales 135623|Vibrionales S Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short k141_30336_9 1116375.VEJY3_08020 3.71e-109 317.0 COG1022@1|root,COG1022@2|Bacteria,1QV90@1224|Proteobacteria,1T2AG@1236|Gammaproteobacteria,1XVNZ@135623|Vibrionales 135623|Vibrionales I Iron-containing redox enzyme - - - - - - - - - - - - Haem_oxygenas_2 k141_25950_1 935836.JAEL01000035_gene1982 3.8e-41 148.0 COG0451@1|root,COG0451@2|Bacteria,1U20S@1239|Firmicutes,4IBHJ@91061|Bacilli,1ZGSD@1386|Bacillus 91061|Bacilli GM ADP-glyceromanno-heptose 6-epimerase activity - - - - - - - - - - - - - k141_960_1 237368.SCABRO_03139 2.27e-30 124.0 COG0569@1|root,COG0569@2|Bacteria,2IXXC@203682|Planctomycetes 203682|Planctomycetes C TRK potassium uptake system protein (TrkA-2) trkA - - ko:K03499 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkA_C,TrkA_N k141_37543_1 218284.CCDN010000006_gene3617 6.49e-136 391.0 COG2390@1|root,COG2390@2|Bacteria,1TP62@1239|Firmicutes,4HAE6@91061|Bacilli,1ZBYA@1386|Bacillus 91061|Bacilli K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain cggR - - ko:K05311 - - - - ko00000,ko03000 - - - Sugar-bind k141_35413_1 1294265.JCM21738_53 2.88e-125 359.0 COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,4HA7D@91061|Bacilli,1ZC0F@1386|Bacillus 91061|Bacilli T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain resD - - ko:K07775 ko02020,map02020 M00458 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C k141_11688_2 1191299.AJYX01000127_gene1151 5.54e-48 159.0 COG0494@1|root,COG0494@2|Bacteria,1RKVK@1224|Proteobacteria,1S86R@1236|Gammaproteobacteria,1XX6U@135623|Vibrionales 135623|Vibrionales L NUDIX domain - - 3.6.1.67 ko:K08310 ko00790,map00790 M00126 R04638 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NUDIX k141_11688_3 493475.GARC_4048 2.42e-101 302.0 COG1250@1|root,COG1250@2|Bacteria,1MV8M@1224|Proteobacteria,1RSQP@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine lcdH - 1.1.1.108 ko:K17735 - - - - ko00000,ko01000 - - - 3HCDH,3HCDH_N k141_23652_2 218284.CCDN010000002_gene2102 1.01e-153 437.0 COG4120@1|root,COG4120@2|Bacteria,1TPDJ@1239|Firmicutes,4HBMY@91061|Bacilli,1ZAWA@1386|Bacillus 91061|Bacilli S Belongs to the binding-protein-dependent transport system permease family - - - ko:K05832 - M00247 - - ko00000,ko00002,ko02000 - - - BPD_transp_2 k141_32837_1 1131730.BAVI_02544 6.11e-94 282.0 COG3173@1|root,COG3173@2|Bacteria,1V5N3@1239|Firmicutes,4HHE7@91061|Bacilli,1ZGDT@1386|Bacillus 91061|Bacilli S Aminoglycoside phosphotransferase - - - - - - - - - - - - APH,APH_6_hur k141_22305_2 223926.28805109 3.48e-215 594.0 COG0454@1|root,COG0456@2|Bacteria,1R407@1224|Proteobacteria,1RPJ2@1236|Gammaproteobacteria,1XSTQ@135623|Vibrionales 135623|Vibrionales K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases yiiD - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10,YiiD_C k141_22305_3 223926.28805108 1.55e-93 273.0 COG1490@1|root,COG1490@2|Bacteria,1RGTV@1224|Proteobacteria,1S61I@1236|Gammaproteobacteria,1XWX3@135623|Vibrionales 135623|Vibrionales J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality dtd GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - ko:K07560 - - - - ko00000,ko01000,ko03016 - - - Tyr_Deacylase k141_22305_4 1116375.VEJY3_00570 1.62e-93 280.0 COG1295@1|root,COG1295@2|Bacteria,1QICW@1224|Proteobacteria,1RMKI@1236|Gammaproteobacteria,1XUTA@135623|Vibrionales 135623|Vibrionales S membrane rbn - - ko:K07058 - - - - ko00000 - - - Virul_fac_BrkB k141_19915_1 1116375.VEJY3_04470 2.63e-185 526.0 COG3014@1|root,COG3014@2|Bacteria,1PD4S@1224|Proteobacteria,1RQ8Y@1236|Gammaproteobacteria,1XUG4@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria - - - ko:K09859 - - - - ko00000 - - - - k141_19915_2 674977.VMC_30870 1.11e-75 226.0 COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,1S3QE@1236|Gammaproteobacteria,1XXB1@135623|Vibrionales 135623|Vibrionales FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases hinT - - ko:K02503 - - - - ko00000,ko04147 - - - HIT k141_19915_3 674977.VMC_30860 0.0 1067.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RQ69@1236|Gammaproteobacteria,1XSI1@135623|Vibrionales 135623|Vibrionales NT methyl-accepting chemotaxis protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - 4HB_MCP_1,MCPsignal k141_19915_4 1116375.VEJY3_04455 6.3e-37 134.0 COG4006@1|root,COG4006@2|Bacteria,1RFA6@1224|Proteobacteria,1S6RM@1236|Gammaproteobacteria,1XU5U@135623|Vibrionales 135623|Vibrionales S Domain of unknown function (DUF1887) VV2376 - - - - - - - - - - - DUF1887 k141_11689_1 218284.CCDN010000007_gene3946 2.38e-124 373.0 COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H9SA@91061|Bacilli,1ZBUK@1386|Bacillus 91061|Bacilli M penicillin-binding protein pbpG GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.4.1.129,3.4.16.4 ko:K21464 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase k141_6891_1 1347368.HG964406_gene6542 1.94e-23 94.4 COG2197@1|root,COG2197@2|Bacteria,1TRXG@1239|Firmicutes,4HCCV@91061|Bacilli,1ZDBY@1386|Bacillus 91061|Bacilli K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain yhcZ - - ko:K02479 - - - - ko00000,ko02022 - - - GerE,Response_reg k141_6891_2 218284.CCDN010000004_gene3092 6.66e-181 509.0 COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,1TR88@1239|Firmicutes,4HBF3@91061|Bacilli,1ZCMJ@1386|Bacillus 91061|Bacilli T Histidine kinase yhcY - 2.7.13.3 ko:K02480 - - - - ko00000,ko01000,ko01001,ko02022 - - - GAF_2,HATPase_c,HisKA_3 k141_37544_1 218284.CCDN010000001_gene1622 1.72e-121 350.0 COG2890@1|root,COG2890@2|Bacteria,1UIWK@1239|Firmicutes,4ISUT@91061|Bacilli 91061|Bacilli J Thiopurine S-methyltransferase (TPMT) - - - - - - - - - - - - Methyltransf_25 k141_18926_1 1265313.HRUBRA_01888 1.92e-49 161.0 COG2127@1|root,COG2127@2|Bacteria,1MZU8@1224|Proteobacteria,1S8Z7@1236|Gammaproteobacteria,1J6Q9@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation clpS GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0050896,GO:0051087 - ko:K06891 - - - - ko00000 - - - ClpS k141_22306_1 1353528.DT23_03760 4.46e-58 199.0 COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,2TR49@28211|Alphaproteobacteria,2XNIG@285107|Thioclava 28211|Alphaproteobacteria E Gamma-glutamyltranspeptidase ggt GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006082,GO:0006508,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008242,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0019538,GO:0019752,GO:0030288,GO:0030313,GO:0031975,GO:0034722,GO:0036374,GO:0042597,GO:0043094,GO:0043102,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070011,GO:0071704,GO:0097264,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept k141_35415_1 218284.CCDN010000001_gene120 9.73e-45 148.0 COG2905@1|root,COG2905@2|Bacteria,1VW3X@1239|Firmicutes,4HJ81@91061|Bacilli,1ZH6S@1386|Bacillus 91061|Bacilli T COG0517 FOG CBS domain ylbB - - - - - - - - - - - CBS k141_30337_1 42565.FP66_00680 1.42e-139 409.0 COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,1RMP2@1236|Gammaproteobacteria,1XNGN@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the IlvD Edd family ilvD - 4.2.1.9 ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R01209,R04441,R05070 RC00468,RC01714 ko00000,ko00001,ko00002,ko01000 - - - ILVD_EDD k141_32838_1 218284.CCDN010000006_gene3536 1.67e-57 190.0 COG1785@1|root,COG1785@2|Bacteria,1TQCI@1239|Firmicutes,4HA27@91061|Bacilli,1ZB3J@1386|Bacillus 91061|Bacilli P Belongs to the alkaline phosphatase family phoB - 3.1.3.1 ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 M00126 R02135,R04620 RC00017 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 - - - Alk_phosphatase k141_32838_2 218284.CCDN010000006_gene3535 1.07e-20 82.8 2E5UW@1|root,330J3@2|Bacteria,1VFMQ@1239|Firmicutes,4HPRZ@91061|Bacilli,1ZIYY@1386|Bacillus 91061|Bacilli S Small acid-soluble spore protein H family sspH - - ko:K06425 - - - - ko00000 - - - SspH k141_4609_5 223926.28808027 5.06e-75 224.0 COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,1S5WR@1236|Gammaproteobacteria,1XXAK@135623|Vibrionales 135623|Vibrionales O Belongs to the thioredoxin family trxA - - ko:K03671 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - Thioredoxin k141_4609_6 1116375.VEJY3_15130 2.12e-310 846.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1XTC7@135623|Vibrionales 135623|Vibrionales JKL DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA rhlB GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575 3.6.4.13 ko:K03732 ko03018,map03018 M00394 - - ko00000,ko00001,ko00002,ko01000,ko03019 - - - DEAD,Helicase_C k141_4609_7 1116375.VEJY3_15135 0.0 907.0 COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,1RN3V@1236|Gammaproteobacteria,1XTYW@135623|Vibrionales 135623|Vibrionales F Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the stringent response , an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities gppA GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006793,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008894,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0015949,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034641,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:1901360 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 - R03409 RC00002 ko00000,ko00001,ko01000 - - - Ppx-GppA k141_4609_8 674977.VMC_02020 0.0 1050.0 COG0673@1|root,COG1091@1|root,COG0673@2|Bacteria,COG1091@2|Bacteria,1N5PQ@1224|Proteobacteria,1S9UU@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Oxidoreductase family, NAD-binding Rossmann fold - - 1.1.1.133 ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777 RC00182 ko00000,ko00001,ko00002,ko01000 - - - GFO_IDH_MocA,RmlD_sub_bind k141_17756_1 223926.28809811 2.41e-241 671.0 COG0845@1|root,COG0845@2|Bacteria,1MUI8@1224|Proteobacteria,1RNK4@1236|Gammaproteobacteria,1XVAQ@135623|Vibrionales 135623|Vibrionales M COG0845 Membrane-fusion protein - - - ko:K02022 - - - - ko00000 - - - Biotin_lipoyl_2,HlyD,HlyD_3 k141_17756_2 1116375.VEJY3_23256 1.49e-188 525.0 COG0668@1|root,COG0668@2|Bacteria,1RA7T@1224|Proteobacteria,1SZY6@1236|Gammaproteobacteria,1Y2XG@135623|Vibrionales 135623|Vibrionales M COG0668 Small-conductance mechanosensitive channel - - - - - - - - - - - - MS_channel k141_17756_3 1116375.VEJY3_23251 8.29e-257 719.0 COG0609@1|root,COG0609@2|Bacteria,1MVA3@1224|Proteobacteria,1RN0J@1236|Gammaproteobacteria,1XT0D@135623|Vibrionales 135623|Vibrionales P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily - - - ko:K02015 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - FecCD k141_21255_1 674977.VMC_36020 1.32e-121 349.0 COG1187@1|root,COG1187@2|Bacteria,1MU6M@1224|Proteobacteria,1RQA9@1236|Gammaproteobacteria,1XTEX@135623|Vibrionales 135623|Vibrionales J Belongs to the pseudouridine synthase RsuA family rsuA GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19 ko:K06183 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 k141_37884_1 1294265.JCM21738_4443 1.59e-117 340.0 29QVJ@1|root,30BVR@2|Bacteria,1U8R4@1239|Firmicutes,4IIP4@91061|Bacilli,1ZGS2@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_3465_1 314278.NB231_06980 1.17e-74 228.0 COG0450@1|root,COG0450@2|Bacteria,1MX2B@1224|Proteobacteria,1RPQV@1236|Gammaproteobacteria,1WVZT@135613|Chromatiales 135613|Chromatiales O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides - - 1.11.1.15 ko:K03386 ko04214,map04214 - - - ko00000,ko00001,ko01000,ko04147 - - - 1-cysPrx_C,AhpC-TSA k141_2249_1 1029823.AFIE01000001_gene2103 1.45e-172 495.0 COG3119@1|root,COG3119@2|Bacteria,1MV92@1224|Proteobacteria,1RPDE@1236|Gammaproteobacteria,3NJ0S@468|Moraxellaceae 1236|Gammaproteobacteria P Sulfatase - - 3.1.6.1 ko:K01130 ko00140,ko00600,map00140,map00600 - R03980,R04856 RC00128,RC00231 ko00000,ko00001,ko01000 - - - Sulfatase,Sulfatase_C k141_15275_1 1453501.JELR01000002_gene911 9.03e-29 119.0 COG1716@1|root,COG3456@1|root,COG1716@2|Bacteria,COG3456@2|Bacteria,1R3R7@1224|Proteobacteria,1RRIU@1236|Gammaproteobacteria,46CUW@72275|Alteromonadaceae 1236|Gammaproteobacteria T Forkhead associated domain - - - ko:K07169,ko:K11894,ko:K11913 ko02025,ko03070,map02025,map03070 - - - ko00000,ko00001,ko02044 3.A.23.1 - - FHA k141_30573_1 935836.JAEL01000029_gene3575 3.31e-39 145.0 COG1368@1|root,COG1368@2|Bacteria,1TRMA@1239|Firmicutes,4HFA5@91061|Bacilli,1ZDG2@1386|Bacillus 91061|Bacilli M Sulfatase - - - - - - - - - - - - Sulfatase k141_30573_2 1196031.ALEG01000047_gene205 5.96e-26 105.0 COG4191@1|root,COG4191@2|Bacteria,1UZ9W@1239|Firmicutes,4HDK2@91061|Bacilli,1ZD85@1386|Bacillus 91061|Bacilli T Histidine kinase - - 2.7.13.3 ko:K07697 ko02020,map02020 M00485 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - 5TM-5TMR_LYT,HATPase_c,HisKA k141_10689_1 1279017.AQYJ01000029_gene3440 8.44e-61 193.0 COG2227@1|root,COG2227@2|Bacteria,1R9ZR@1224|Proteobacteria,1S27B@1236|Gammaproteobacteria,4672C@72275|Alteromonadaceae 1236|Gammaproteobacteria H Methyltransferase domain - - - - - - - - - - - - Methyltransf_23 k141_36585_1 218284.CCDN010000002_gene2254 5.57e-122 363.0 COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TPJ8@1239|Firmicutes,4HA8X@91061|Bacilli,1ZC2B@1386|Bacillus 91061|Bacilli G IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar ptsG - 2.7.1.208 ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 M00265,M00266,M00268,M00270,M00272,M00303,M00806 R02738,R02780,R04111,R04394,R05132,R08559 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.1,4.A.1.1.11,4.A.1.1.12 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC k141_34445_1 218284.CCDN010000004_gene3130 3.42e-122 348.0 COG1595@1|root,COG1595@2|Bacteria,1VB37@1239|Firmicutes,4HMZ2@91061|Bacilli,1ZCWY@1386|Bacillus 91061|Bacilli K Belongs to the sigma-70 factor family. ECF subfamily sigY - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4,Sigma70_r4_2 k141_31737_1 1453501.JELR01000002_gene1048 7.11e-112 330.0 COG0454@1|root,COG0456@2|Bacteria,1MVZ2@1224|Proteobacteria,1RSC5@1236|Gammaproteobacteria,465P6@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG0456 Acetyltransferases - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10,DUF3335 k141_10690_1 218284.CCDN010000001_gene1956 2.4e-96 290.0 COG2718@1|root,COG2718@2|Bacteria,1TQIN@1239|Firmicutes,4HBIH@91061|Bacilli,1ZATH@1386|Bacillus 91061|Bacilli S Belongs to the UPF0229 family yhbH - - ko:K09786 - - - - ko00000 - - - DUF444 k141_21257_1 1294265.JCM21738_4140 1.54e-73 221.0 COG5609@1|root,COG5609@2|Bacteria,1V6YC@1239|Firmicutes,4HIMH@91061|Bacilli,1ZH3T@1386|Bacillus 91061|Bacilli S Uncharacterized conserved protein (DUF2294) ybcI - - - - - - - - - - - DUF2294 k141_34446_1 1423321.AS29_17355 1.73e-29 113.0 COG0010@1|root,COG0010@2|Bacteria,1TP2A@1239|Firmicutes,4HCKQ@91061|Bacilli,1ZBPI@1386|Bacillus 91061|Bacilli E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide hutG - 3.5.3.8 ko:K01479 ko00340,ko01100,map00340,map01100 M00045 R02285 RC00221,RC00681 ko00000,ko00001,ko00002,ko01000 - - - Arginase k141_34446_2 1423321.AS29_17350 1.61e-45 158.0 COG1228@1|root,COG1228@2|Bacteria,1TP2J@1239|Firmicutes,4HAVY@91061|Bacilli,1ZDE5@1386|Bacillus 91061|Bacilli Q Imidazolone-5-propionate hydrolase hutI - 3.5.2.7 ko:K01468 ko00340,ko01100,map00340,map01100 M00045 R02288 RC00683 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU39370 Amidohydro_1,Amidohydro_3 k141_30574_1 498211.CJA_1315 8.34e-106 323.0 COG2211@1|root,COG2211@2|Bacteria,1MVUM@1224|Proteobacteria,1RP5J@1236|Gammaproteobacteria,1FGD5@10|Cellvibrio 1236|Gammaproteobacteria G MFS/sugar transport protein - - - ko:K03292 - - - - ko00000 2.A.2 - - MFS_2 k141_28295_1 218284.CCDN010000002_gene2016 2.41e-207 580.0 COG0064@1|root,COG0064@2|Bacteria,1TPG3@1239|Firmicutes,4HAFB@91061|Bacilli,1ZB3K@1386|Bacillus 91061|Bacilli J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatB GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 ko:K02434 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - GatB_N,GatB_Yqey k141_28295_2 218284.CCDN010000002_gene2015 1.73e-154 444.0 COG0154@1|root,COG0154@2|Bacteria,1TP0C@1239|Firmicutes,4HBAZ@91061|Bacilli,1ZAT1@1386|Bacillus 91061|Bacilli J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) gatA - 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Amidase k141_4648_1 1116375.VEJY3_18116 8.18e-117 338.0 COG3384@1|root,COG3384@2|Bacteria,1MW77@1224|Proteobacteria,1RQIK@1236|Gammaproteobacteria,1XX4P@135623|Vibrionales 135623|Vibrionales S Catalytic LigB subunit of aromatic ring-opening dioxygenase - - 1.13.11.8 ko:K04101 ko00362,ko00624,ko00627,ko01120,map00362,map00624,map00627,map01120 - R01632,R03550,R04280,R09565 RC00233,RC00387,RC00535,RC02567,RC02694 br01602,ko00000,ko00001,ko01000 - - - LigB k141_4648_3 1116375.VEJY3_18106 8.92e-216 595.0 COG3618@1|root,COG3618@2|Bacteria,1N2QM@1224|Proteobacteria,1RQ8V@1236|Gammaproteobacteria,1XX15@135623|Vibrionales 135623|Vibrionales S Amidohydrolase - - 3.1.1.57 ko:K10221 ko00362,ko00627,ko01120,map00362,map00627,map01120 - R04277 RC03110 ko00000,ko00001,ko01000 - - - Amidohydro_2 k141_4648_4 1116375.VEJY3_18101 2.6e-236 652.0 COG2828@1|root,COG2828@2|Bacteria,1MXVV@1224|Proteobacteria,1RNE6@1236|Gammaproteobacteria,1XWGM@135623|Vibrionales 135623|Vibrionales S PrpF protein - - 5.3.2.8 ko:K16514 ko00362,ko01120,map00362,map01120 - R07839 RC02426 ko00000,ko00001,ko01000 - - - PrpF k141_4648_5 1116375.VEJY3_18096 3.14e-153 431.0 COG0684@1|root,COG0684@2|Bacteria,1MW9P@1224|Proteobacteria,1RNV3@1236|Gammaproteobacteria,1XSIS@135623|Vibrionales 135623|Vibrionales H Aldolase/RraA - - 4.1.3.17 ko:K10218 ko00362,ko00660,ko01120,map00362,map00660,map01120 - R00008,R00350 RC00067,RC00502,RC01205 ko00000,ko00001,ko01000 - - - RraA-like k141_4648_6 1116375.VEJY3_18091 2.88e-253 694.0 COG2159@1|root,COG2159@2|Bacteria,1MVHB@1224|Proteobacteria,1RMYJ@1236|Gammaproteobacteria,1XVYI@135623|Vibrionales 135623|Vibrionales S Amidohydrolase - - 4.2.1.83 ko:K10220 ko00362,ko01120,map00362,map01120 - R04478 RC00498 ko00000,ko00001,ko01000 - - - Amidohydro_2 k141_4648_7 1116375.VEJY3_18086 1.58e-177 497.0 COG0169@1|root,COG0169@2|Bacteria,1Q95E@1224|Proteobacteria,1S38H@1236|Gammaproteobacteria,1Y03H@135623|Vibrionales 135623|Vibrionales C Shikimate dehydrogenase substrate binding domain - - 1.1.1.25 ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000 - - - Shikimate_dh_N k141_4648_8 1116375.VEJY3_18081 9.6e-94 274.0 COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,1S3PX@1236|Gammaproteobacteria,1XY5C@135623|Vibrionales 135623|Vibrionales E Catalyzes a trans-dehydration via an enolate intermediate - - 4.2.1.10 ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03084 RC00848 ko00000,ko00001,ko00002,ko01000 - - - DHquinase_II k141_21258_1 218284.CCDN010000001_gene1867 2.42e-114 341.0 COG3845@1|root,COG3845@2|Bacteria,1UYQA@1239|Firmicutes,4HVSH@91061|Bacilli,1ZS12@1386|Bacillus 91061|Bacilli S ABC transporter, ATP-binding protein yufO - 3.6.3.17 ko:K02056 - M00221 - - ko00000,ko00002,ko01000,ko02000 3.A.1.2 - - ABC_tran k141_34447_1 1117379.BABA_06331 4e-73 246.0 COG1074@1|root,COG1074@2|Bacteria,1TQ35@1239|Firmicutes,4HA64@91061|Bacilli,1ZBG6@1386|Bacillus 91061|Bacilli L ATP-dependent helicase nuclease subunit A addA GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 3.6.4.12 ko:K16898 - - - - ko00000,ko01000,ko03400 - - - PDDEXK_1,UvrD-helicase,UvrD_C k141_33182_1 1294265.JCM21738_127 4.49e-41 145.0 COG0457@1|root,COG0457@2|Bacteria,1TT97@1239|Firmicutes,4HAIA@91061|Bacilli,1ZAZM@1386|Bacillus 91061|Bacilli S COG0457 FOG TPR repeat ypiA - - - - - - - - - - - TPR_16,TPR_19,TPR_2,TPR_7,TPR_8 k141_33182_2 935836.JAEL01000006_gene2761 4.87e-100 292.0 COG5582@1|root,COG5582@2|Bacteria,1V5KV@1239|Firmicutes,4HEE0@91061|Bacilli,1ZB4J@1386|Bacillus 91061|Bacilli S Belongs to the UPF0302 family ypiB - - - - - - - - - - - IDEAL,UPF0302 k141_10691_1 861299.J421_3848 2.03e-131 392.0 COG0443@1|root,COG0443@2|Bacteria,1ZT75@142182|Gemmatimonadetes 142182|Gemmatimonadetes O Heat shock 70 kDa protein dnaK - - ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 - - HSP70 k141_3469_1 218284.CCDN010000004_gene3125 2.22e-58 200.0 COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,4HADT@91061|Bacilli,1ZCKV@1386|Bacillus 91061|Bacilli KT Sigma-54 interaction domain - - - - - - - - - - - - HTH_12,HTH_8,PAS,PAS_9,Sigma54_activat k141_36588_1 997296.PB1_02110 1.73e-12 62.0 COG1925@1|root,COG1925@2|Bacteria,1VA0R@1239|Firmicutes,4HKGA@91061|Bacilli,1ZHX7@1386|Bacillus 91061|Bacilli G phosphocarrier protein HPr ptsH GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0043610,GO:0044424,GO:0044464,GO:0050789,GO:0065007 - ko:K11189 - - - - ko00000,ko02000 4.A.2.1 - - PTS-HPr k141_8090_1 1116375.VEJY3_23771 3.83e-33 118.0 COG0366@1|root,COG0366@2|Bacteria,1QJND@1224|Proteobacteria,1THP3@1236|Gammaproteobacteria,1XWZW@135623|Vibrionales 135623|Vibrionales M Alpha amylase catalytic - - - - - - - - - - - - - k141_8090_2 1116375.VEJY3_23766 0.0 951.0 COG0366@1|root,COG0366@2|Bacteria,1PDIR@1224|Proteobacteria,1RRUN@1236|Gammaproteobacteria,1Y2KA@135623|Vibrionales 135623|Vibrionales G Alpha amylase, catalytic domain - - - - - - - - - - - - Alpha-amylase k141_30575_1 1265505.ATUG01000002_gene2218 1.03e-60 197.0 COG2207@1|root,COG2207@2|Bacteria,1QYD9@1224|Proteobacteria,43CBM@68525|delta/epsilon subdivisions 1224|Proteobacteria K Bacterial regulatory helix-turn-helix proteins, AraC family - - 2.1.1.63 ko:K10778 - - - - ko00000,ko01000,ko03000,ko03400 - - - DNA_binding_1,HTH_AraC k141_28296_1 218284.CCDN010000001_gene1138 1.74e-93 278.0 COG0413@1|root,COG0413@2|Bacteria,1TPZA@1239|Firmicutes,4H9S8@91061|Bacilli,1ZAWV@1386|Bacillus 91061|Bacilli H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate panB - 2.1.2.11 ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R01226 RC00022,RC00200 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU22430 Pantoate_transf k141_17761_1 1294265.JCM21738_3183 1.48e-07 52.4 COG0861@1|root,COG0861@2|Bacteria,1UVIJ@1239|Firmicutes,4HEYG@91061|Bacilli,1ZQM8@1386|Bacillus 91061|Bacilli P COG0861 Membrane protein TerC, possibly involved in tellurium resistance yceF - - - - - - - - - - - TerC k141_17761_2 1294265.JCM21738_3184 2.35e-130 370.0 2C2Z4@1|root,2ZV7K@2|Bacteria,1V3JN@1239|Firmicutes,4HHVS@91061|Bacilli,1ZGAN@1386|Bacillus 91061|Bacilli S YpjP-like protein ypjP - - - - - - - - - - - YpjP k141_21259_1 1116375.VEJY3_06730 3.91e-78 237.0 COG4126@1|root,COG4126@2|Bacteria,1MVNB@1224|Proteobacteria,1RQXU@1236|Gammaproteobacteria,1XXDY@135623|Vibrionales 135623|Vibrionales E Asp/Glu/Hydantoin racemase - - 5.1.99.3 ko:K16841 ko00230,ko01120,map00230,map01120 - R03925 RC01027 ko00000,ko00001,ko01000 - - - Asp_Glu_race k141_3471_1 1122939.ATUD01000002_gene1217 1.51e-36 133.0 COG0682@1|root,COG0682@2|Bacteria,2GKSS@201174|Actinobacteria,4CQIT@84995|Rubrobacteria 84995|Rubrobacteria M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins - - - ko:K13292 - - - - ko00000,ko01000 - - - LGT k141_10693_1 218284.CCDN010000008_gene4181 1.96e-74 225.0 COG4297@1|root,COG4297@2|Bacteria,1V6MJ@1239|Firmicutes,4HJGB@91061|Bacilli,1ZGYD@1386|Bacillus 91061|Bacilli S Cupin domain yjlB - - - - - - - - - - - Cupin_1,Cupin_2 k141_2252_2 1122137.AQXF01000007_gene3600 6.21e-216 613.0 COG0644@1|root,COG0644@2|Bacteria,1R41S@1224|Proteobacteria,2TW03@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Tryptophan halogenase - - 1.14.19.9 ko:K14266 ko00404,ko01130,map00404,map01130 M00789,M00790 R09570 RC00949 ko00000,ko00001,ko00002,ko01000 - - - Trp_halogenase k141_28297_1 498211.CJA_2769 9.52e-109 330.0 COG3534@1|root,COG3534@2|Bacteria,1PPWJ@1224|Proteobacteria,1RQ0J@1236|Gammaproteobacteria,1FGEM@10|Cellvibrio 1236|Gammaproteobacteria G Alpha-L-arabinofuranosidase C-terminus abfA - 3.2.1.55 ko:K01209 ko00520,map00520 - R01762 - ko00000,ko00001,ko01000 - GH51 - Alpha-L-AF_C k141_36589_2 218284.CCDN010000001_gene1150 2.77e-223 641.0 COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H9SA@91061|Bacilli,1ZAXY@1386|Bacillus 91061|Bacilli M penicillin-binding protein ponA GO:0005575,GO:0005576 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase k141_2253_1 1042377.AFPJ01000036_gene1173 6.06e-82 262.0 COG0665@1|root,COG4121@1|root,COG0665@2|Bacteria,COG4121@2|Bacteria,1MZW5@1224|Proteobacteria,1RMTE@1236|Gammaproteobacteria,464VK@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 mnmC GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0004808,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016491,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363 2.1.1.61 ko:K15461 - - R00601,R08702 RC00003,RC00053,RC00060,RC01483 ko00000,ko01000,ko03016 - - - DAO,Methyltransf_30 k141_4653_1 665952.HMPREF1015_00851 1.53e-41 155.0 COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1TPMS@1239|Firmicutes,4HAQD@91061|Bacilli,1ZATW@1386|Bacillus 91061|Bacilli NT COG0643 Chemotaxis protein histidine kinase and related kinases cheA - 2.7.13.3 ko:K03407 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt,P2 k141_15276_1 1238184.CM001792_gene1615 1.62e-74 251.0 COG1298@1|root,COG1298@2|Bacteria,1TQBM@1239|Firmicutes,4H9XU@91061|Bacilli,23JEA@182709|Oceanobacillus 91061|Bacilli NU Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin flhA - - ko:K02400 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 - - FHIPEP k141_15276_2 1121878.AUGL01000022_gene3689 1.36e-12 72.8 COG4787@1|root,COG4787@2|Bacteria,1NZWQ@1224|Proteobacteria,1RNVX@1236|Gammaproteobacteria 1236|Gammaproteobacteria N flagellar basal body flgF - - ko:K02391 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C k141_15276_3 1458275.AZ34_02090 7.55e-09 57.4 COG4786@1|root,COG4786@2|Bacteria,1MVMA@1224|Proteobacteria,2VH7A@28216|Betaproteobacteria,4ABFE@80864|Comamonadaceae 28216|Betaproteobacteria N Belongs to the flagella basal body rod proteins family flgG - - ko:K02392 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C k141_36590_2 1407650.BAUB01000012_gene2073 2.16e-12 69.7 COG0665@1|root,COG2022@1|root,COG0665@2|Bacteria,COG2022@2|Bacteria,1FZYU@1117|Cyanobacteria,1GYHY@1129|Synechococcus 1117|Cyanobacteria H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S thiG - 2.8.1.10 ko:K03149 ko00730,ko01100,map00730,map01100 - R10247 RC03096,RC03097,RC03461 ko00000,ko00001,ko01000 - - - DAO,ThiG k141_21262_1 218284.CCDN010000005_gene3228 3.02e-98 315.0 COG3857@1|root,COG3857@2|Bacteria,1TQJW@1239|Firmicutes,4HAY6@91061|Bacilli,1ZC70@1386|Bacillus 91061|Bacilli L ATP-dependent helicase deoxyribonuclease subunit B rexB GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0004527,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.6.4.12 ko:K16899 - - - - ko00000,ko01000,ko03400 - - - Exonuc_V_gamma,PDDEXK_1,UvrD_C k141_33187_1 1294265.JCM21738_492 3.3e-141 416.0 COG1511@1|root,COG1511@2|Bacteria,1TRMJ@1239|Firmicutes,4HB2N@91061|Bacilli,1ZBC1@1386|Bacillus 91061|Bacilli S domain protein - - - - - - - - - - - - - k141_4654_1 1131730.BAVI_12514 1.83e-12 62.0 2E2C2@1|root,32XH4@2|Bacteria,1VDJY@1239|Firmicutes,4HMBA@91061|Bacilli,1ZIXP@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2535) ypmP - - - - - - - - - - - DUF2535 k141_4654_2 218284.CCDN010000001_gene1202 7.64e-29 110.0 COG1307@1|root,COG1307@2|Bacteria,1TRZ4@1239|Firmicutes,4HBR8@91061|Bacilli,1ZCJP@1386|Bacillus 91061|Bacilli S protein conserved in bacteria degV - - - - - - - - - - - DegV k141_28300_1 190486.XAC4225 5.5e-93 284.0 COG2115@1|root,COG2115@2|Bacteria,1MXS2@1224|Proteobacteria,1RN5Y@1236|Gammaproteobacteria,1X4B9@135614|Xanthomonadales 135614|Xanthomonadales G Belongs to the xylose isomerase family xylA GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009045,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0071704,GO:1901575 5.3.1.5 ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 - R00878,R01432 RC00376,RC00516 ko00000,ko00001,ko01000 - - - - k141_4655_1 1123377.AUIV01000013_gene2311 4.5e-69 226.0 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1RMQ4@1236|Gammaproteobacteria,1X3W8@135614|Xanthomonadales 135614|Xanthomonadales IQ Activates fatty acids by binding to coenzyme A rpfB - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding,AMP-binding_C k141_30578_1 1116375.VEJY3_20376 7.11e-144 421.0 COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,1RMNZ@1236|Gammaproteobacteria,1XUS0@135623|Vibrionales 1236|Gammaproteobacteria F Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA - - 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 - - - AMP-binding,AMP-binding_C k141_17764_1 218284.CCDN010000001_gene1811 1.14e-119 353.0 COG2720@1|root,COG2720@2|Bacteria,1TSH8@1239|Firmicutes,4HCPD@91061|Bacilli,1ZBNK@1386|Bacillus 91061|Bacilli V vancomycin resistance protein yoaR - - - - - - - - - - - PG_binding_4,VanW k141_17764_2 218284.CCDN010000001_gene1810 5.93e-64 203.0 COG1388@1|root,COG1388@2|Bacteria,1V5FY@1239|Firmicutes,4HFU9@91061|Bacilli,1ZDDF@1386|Bacillus 91061|Bacilli M LysM domain - - - - - - - - - - - - - k141_34454_2 1033740.CAEW01000026_gene528 7.97e-42 152.0 2CEGT@1|root,2Z7ZB@2|Bacteria,1TP3Y@1239|Firmicutes,4HDQK@91061|Bacilli,26HDM@186818|Planococcaceae 91061|Bacilli S Phage portal protein, SPP1 Gp6-like - - - - - - - - - - - - Phage_prot_Gp6 k141_10694_1 345219.Bcoa_0029 0.000109 45.4 2D5MU@1|root,32TJF@2|Bacteria,1V9ZA@1239|Firmicutes,4HMQI@91061|Bacilli,1ZFEI@1386|Bacillus 91061|Bacilli - - ylxL - - - - - - - - - - - - k141_10694_2 941639.BCO26_1162 1.56e-148 421.0 COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,4H9N5@91061|Bacilli,1ZAYU@1386|Bacillus 91061|Bacilli J Belongs to the universal ribosomal protein uS2 family rpsB GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02967 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S2 k141_10694_3 441769.ABFU01000029_gene1094 1.45e-74 231.0 COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,4HBDV@91061|Bacilli,1ZB7R@1386|Bacillus 91061|Bacilli J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome tsf GO:0001871,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005623,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0019538,GO:0030246,GO:0030247,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 - ko:K02357 - - - - ko00000,ko03012,ko03029 - - - EF_TS k141_8120_1 218284.CCDN010000001_gene560 1.01e-100 294.0 COG1309@1|root,COG1309@2|Bacteria,1TRSH@1239|Firmicutes,4H9RC@91061|Bacilli,1ZAU5@1386|Bacillus 91061|Bacilli K Transcriptional regulator fadR GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - ko:K13770 - - - - ko00000,ko03000 - - - TetR_C_4,TetR_N k141_28339_1 1294265.JCM21738_1837 2.65e-185 527.0 COG1251@1|root,COG1251@2|Bacteria,1TQYX@1239|Firmicutes,4HASM@91061|Bacilli,1ZQ9P@1386|Bacillus 91061|Bacilli C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family nirB - 1.7.1.15 ko:K00362 ko00910,ko01120,map00910,map01120 M00530 R00787 RC00176 ko00000,ko00001,ko00002,ko01000 - - - Fer2_BFD,NIR_SIR,NIR_SIR_ferr,Pyr_redox_2 k141_36603_1 1121939.L861_08945 1.49e-54 182.0 COG4675@1|root,COG5301@1|root,COG4675@2|Bacteria,COG5301@2|Bacteria,1MWNN@1224|Proteobacteria,1RR74@1236|Gammaproteobacteria 1236|Gammaproteobacteria M tail collar domain protein H - - - - - - - - - - - Collar,DUF3751,Phage_fiber_2 k141_21302_1 1294265.JCM21738_196 1.19e-52 165.0 COG4309@1|root,COG4309@2|Bacteria,1VHYE@1239|Firmicutes,4HM7G@91061|Bacilli,1ZJIM@1386|Bacillus 91061|Bacilli S Uncharacterized conserved protein (DUF2249) - - - - - - - - - - - - DUF2249 k141_4683_1 1123377.AUIV01000001_gene965 1.98e-42 157.0 COG1629@1|root,COG4771@2|Bacteria,1MWKN@1224|Proteobacteria,1RMM6@1236|Gammaproteobacteria,1X2Y6@135614|Xanthomonadales 135614|Xanthomonadales P TonB-dependent Receptor Plug Domain - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_33221_1 1294265.JCM21738_2444 4.93e-170 479.0 COG2208@1|root,COG2208@2|Bacteria,1TQY5@1239|Firmicutes,4HAF6@91061|Bacilli,1ZBIB@1386|Bacillus 91061|Bacilli KT phosphatase rsbU - 3.1.3.3 ko:K07315 - - - - ko00000,ko01000,ko03021 - - - RsbU_N,SpoIIE k141_37920_1 1453501.JELR01000002_gene388 0.0 1145.0 COG1251@1|root,COG1251@2|Bacteria,1MW58@1224|Proteobacteria,1RNGY@1236|Gammaproteobacteria,4656K@72275|Alteromonadaceae 1236|Gammaproteobacteria C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family nirB - 1.7.1.15 ko:K00362 ko00910,ko01120,map00910,map01120 M00530 R00787 RC00176 ko00000,ko00001,ko00002,ko01000 - - - Fer2_BFD,NIR_SIR,NIR_SIR_ferr,Pyr_redox_2 k141_36604_1 187272.Mlg_1471 7.52e-121 376.0 COG0209@1|root,COG1372@1|root,COG0209@2|Bacteria,COG1372@2|Bacteria,1MUJ8@1224|Proteobacteria,1RQUR@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen nrdZ - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Intein_splicing,LAGLIDADG_3,Ribonuc_red_lgC,Ribonuc_red_lgN k141_33222_1 1120953.AUBH01000010_gene121 1.25e-53 190.0 COG1629@1|root,COG4206@1|root,COG1629@2|Bacteria,COG4206@2|Bacteria,1QU0Y@1224|Proteobacteria,1T1KC@1236|Gammaproteobacteria,46DDA@72275|Alteromonadaceae 1236|Gammaproteobacteria HP TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec k141_8121_1 218284.CCDN010000002_gene2131 3.33e-216 600.0 COG0513@1|root,COG0513@2|Bacteria,1TQ9R@1239|Firmicutes,4HANR@91061|Bacilli,1ZC9I@1386|Bacillus 91061|Bacilli L COG0513 Superfamily II DNA and RNA helicases yfmL GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - - - - - - - - - - DEAD,Helicase_C k141_16611_2 218284.CCDN010000001_gene1451 2.1e-35 120.0 COG2104@1|root,COG2104@2|Bacteria 2|Bacteria H thiamine diphosphate biosynthetic process thiS - - ko:K03154 ko04122,map04122 - - - ko00000,ko00001 - - iJN678.ycf40 ThiS k141_21304_2 315750.BPUM_1973 4.65e-78 240.0 COG0414@1|root,COG0414@2|Bacteria,1TP7A@1239|Firmicutes,4HAIQ@91061|Bacilli,1ZAV5@1386|Bacillus 91061|Bacilli H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate panC GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 M00119 R02473 RC00096,RC00141 ko00000,ko00001,ko00002,ko01000 - - - Pantoate_ligase k141_36605_1 333138.LQ50_11775 2.29e-34 120.0 29ZSK@1|root,30MTJ@2|Bacteria,1UAM9@1239|Firmicutes,4IKZZ@91061|Bacilli,1ZIJ4@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_36605_2 665959.HMPREF1013_02896 2.18e-32 116.0 2CHF3@1|root,32VSH@2|Bacteria,1VE4P@1239|Firmicutes,4HKKU@91061|Bacilli,1ZMJB@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_33223_1 218284.CCDN010000002_gene2279 2.44e-138 400.0 COG0842@1|root,COG0842@2|Bacteria,1UYSF@1239|Firmicutes,4HEYE@91061|Bacilli,1ZCKQ@1386|Bacillus 91061|Bacilli V ABC-2 type transporter - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane,ABC2_membrane_3 k141_34475_1 218284.CCDN010000008_gene4177 2.65e-167 471.0 COG1242@1|root,COG1242@2|Bacteria,1TQ57@1239|Firmicutes,4H9N8@91061|Bacilli,1ZBM1@1386|Bacillus 91061|Bacilli S Fe-S oxidoreductase ytqA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K07139 - - - - ko00000 - - - Radical_SAM,Radical_SAM_C k141_16612_1 1453501.JELR01000002_gene129 3.4e-169 484.0 COG3203@1|root,COG3203@2|Bacteria,1MX4Q@1224|Proteobacteria,1RY5B@1236|Gammaproteobacteria,4654M@72275|Alteromonadaceae 1236|Gammaproteobacteria M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - - - - - - - - - - Porin_2 k141_4688_1 1211777.BN77_1921 1.66e-23 104.0 COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2U1YP@28211|Alphaproteobacteria,4B9W3@82115|Rhizobiaceae 28211|Alphaproteobacteria Q COG2931, RTX toxins and related Ca2 -binding proteins - - - - - - - - - - - - He_PIG,HemolysinCabind,VWA_2 k141_34606_3 1116375.VEJY3_15916 3.01e-294 807.0 COG0122@1|root,COG2169@1|root,COG0122@2|Bacteria,COG2169@2|Bacteria,1QTXM@1224|Proteobacteria,1RNQB@1236|Gammaproteobacteria,1XUD0@135623|Vibrionales 135623|Vibrionales K COG2169 Adenosine deaminase ada - 3.2.2.21 ko:K13529 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03000,ko03400 - - - Ada_Zn_binding,AlkA_N,HTH_18,HhH-GPD k141_197_3 1116375.VEJY3_21991 5.62e-54 170.0 COG4392@1|root,COG4392@2|Bacteria,1N6Z1@1224|Proteobacteria,1SCAB@1236|Gammaproteobacteria,1XYAS@135623|Vibrionales 135623|Vibrionales S branched-chain amino acid - - - - - - - - - - - - AzlD k141_197_4 1219076.N646_4634 5.72e-50 164.0 COG1296@1|root,COG1296@2|Bacteria,1MVGN@1224|Proteobacteria,1S2AK@1236|Gammaproteobacteria,1XSZ2@135623|Vibrionales 135623|Vibrionales E branched-chain amino acid permease (azaleucine resistance) - - - - - - - - - - - - AzlC k141_14435_1 1166016.W5S_0296 2.73e-16 76.3 COG1137@1|root,COG1137@2|Bacteria,1MU8M@1224|Proteobacteria,1RPW1@1236|Gammaproteobacteria,1MRX7@122277|Pectobacterium 1236|Gammaproteobacteria S ABC transporter lptB GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - ko:K06861 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko01000,ko02000 1.B.42.1 - - ABC_tran,BCA_ABC_TP_C k141_3731_1 1453501.JELR01000002_gene116 2.9e-230 658.0 COG1629@1|root,COG4771@2|Bacteria,1MUNK@1224|Proteobacteria,1RN9S@1236|Gammaproteobacteria,464ZY@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_36957_1 667014.Thein_2043 0.000258 44.3 COG2221@1|root,COG2221@2|Bacteria,2GHX3@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria C Nitrite and sulphite reductase 4Fe-4S domain - - - - - - - - - - - - Fer4,Fer4_6,NIR_SIR,PCP_red k141_36957_2 1168065.DOK_17865 2e-139 397.0 COG0421@1|root,COG0421@2|Bacteria,1QUUH@1224|Proteobacteria,1T268@1236|Gammaproteobacteria,1J83V@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E COG0421 Spermidine synthase - - - - - - - - - - - - - k141_36957_3 411154.GFO_0060 2.13e-37 126.0 COG4628@1|root,COG4628@2|Bacteria,4NUS1@976|Bacteroidetes,1I55S@117743|Flavobacteriia 976|Bacteroidetes S conserved protein (DUF2132) - - - - - - - - - - - - VF530 k141_16772_1 1453501.JELR01000002_gene443 2.75e-159 457.0 COG0733@1|root,COG0733@2|Bacteria,1MUZJ@1224|Proteobacteria,1RPCT@1236|Gammaproteobacteria,4657F@72275|Alteromonadaceae 1236|Gammaproteobacteria S Sodium:neurotransmitter symporter family - - - ko:K03308 - - - - ko00000 2.A.22.4,2.A.22.5 - - SNF k141_7264_1 1294265.JCM21738_49 1.13e-208 587.0 COG1333@1|root,COG1333@2|Bacteria,1TQ6C@1239|Firmicutes,4HAFD@91061|Bacilli,1ZBB3@1386|Bacillus 91061|Bacilli O COG1333 ResB protein required for cytochrome c biosynthesis resB - - ko:K07399 - - - - ko00000 - - - ResB k141_14436_1 441769.ABFU01000066_gene1950 2.35e-84 254.0 COG0778@1|root,COG0778@2|Bacteria,1UXYI@1239|Firmicutes,4HBMN@91061|Bacilli,1ZQ88@1386|Bacillus 91061|Bacilli C nitroreductase yodC - - - - - - - - - - - Nitroreductase k141_22738_1 1121373.KB903631_gene624 2.1e-84 259.0 COG2197@1|root,COG2197@2|Bacteria,4NQZ6@976|Bacteroidetes,47XFK@768503|Cytophagia 976|Bacteroidetes KT helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE,PAS_3 k141_27449_1 158500.BV97_03417 3.09e-09 58.2 COG2802@1|root,COG2802@2|Bacteria,1NV9N@1224|Proteobacteria,2TQZ4@28211|Alphaproteobacteria,2K0QK@204457|Sphingomonadales 204457|Sphingomonadales S to the N-terminal domain of Lon protease - - - ko:K07157 - - - - ko00000 - - - LON_substr_bdg k141_27449_2 639030.JHVA01000001_gene238 1.11e-19 86.7 COG0428@1|root,COG0428@2|Bacteria,3Y4A7@57723|Acidobacteria,2JJ1K@204432|Acidobacteriia 204432|Acidobacteriia P ZIP Zinc transporter - - - ko:K07238,ko:K16267 - - - - ko00000,ko02000 2.A.5.4.11,2.A.5.5 - - Zip k141_1270_1 1479235.KK366039_gene2986 5.53e-203 567.0 COG0654@1|root,COG0654@2|Bacteria,1N8DE@1224|Proteobacteria,1S5UK@1236|Gammaproteobacteria 1236|Gammaproteobacteria CH lycopene cyclase crtY - 5.5.1.19 ko:K06443 ko00906,ko01100,ko01110,map00906,map01100,map01110 M00097 R03824,R04801,R05341,R06962,R07856 RC01004,RC01964 ko00000,ko00001,ko00002,ko01000 - - - Lycopene_cycl k141_23881_1 1453501.JELR01000001_gene1927 8.89e-89 269.0 COG2171@1|root,COG2171@2|Bacteria,1MYKK@1224|Proteobacteria,1RM8X@1236|Gammaproteobacteria,46580@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA dapD GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008666,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.117 ko:K00674 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R04365 RC00004,RC01136 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_1530 Hexapep_2,THDPS_M,THDPS_N k141_23881_2 1453501.JELR01000001_gene1928 2.82e-44 145.0 COG1393@1|root,COG1393@2|Bacteria,1MZ6S@1224|Proteobacteria,1S8TR@1236|Gammaproteobacteria,467VK@72275|Alteromonadaceae 1236|Gammaproteobacteria P Belongs to the ArsC family yffB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.20.4.1 ko:K00537 - - - - ko00000,ko01000 - - - ArsC k141_29839_1 1123252.ATZF01000011_gene3247 2.9e-67 213.0 COG0090@1|root,COG0090@2|Bacteria,1TP9X@1239|Firmicutes,4HAE8@91061|Bacilli,27B39@186824|Thermoactinomycetaceae 91061|Bacilli J Ribosomal Proteins L2, C-terminal domain rplB GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02886 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L2,Ribosomal_L2_C k141_29839_2 909663.KI867150_gene2587 1.39e-23 93.2 COG0089@1|root,COG0089@2|Bacteria,1MZXX@1224|Proteobacteria,42V3Y@68525|delta/epsilon subdivisions,2WRMX@28221|Deltaproteobacteria,2MQN2@213462|Syntrophobacterales 28221|Deltaproteobacteria J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome rplW GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02892 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L23 k141_12016_1 1453501.JELR01000002_gene1205 3.94e-101 314.0 COG1404@1|root,COG5640@1|root,COG1404@2|Bacteria,COG5640@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria,464PM@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG1404 Subtilisin-like serine proteases - GO:0005575,GO:0005576 - ko:K14645 ko02024,map02024 - - - ko00000,ko00001,ko01000,ko01002,ko03110 - - - PKD,PPC,P_proprotein,Peptidase_S8 k141_12016_2 555778.Hneap_1375 5.18e-172 488.0 COG1064@1|root,COG1064@2|Bacteria,1MUTT@1224|Proteobacteria,1RN4D@1236|Gammaproteobacteria,1WXPM@135613|Chromatiales 135613|Chromatiales S PFAM Alcohol dehydrogenase - - - ko:K12957,ko:K13979 - - - - ko00000,ko01000 - - - ADH_N,ADH_zinc_N k141_12016_3 1453501.JELR01000002_gene1204 2.75e-109 316.0 COG2128@1|root,COG2128@2|Bacteria,1RBG0@1224|Proteobacteria,1S26Z@1236|Gammaproteobacteria,466DC@72275|Alteromonadaceae 1236|Gammaproteobacteria S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - - - - - - - - - - CMD k141_16773_1 1386089.N865_06245 5.08e-26 110.0 COG0703@1|root,COG0703@2|Bacteria,2GVZX@201174|Actinobacteria,4FHQ7@85021|Intrasporangiaceae 201174|Actinobacteria E Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate - - - - - - - - - - - - - k141_33401_1 1116375.VEJY3_10465 2.69e-304 839.0 COG3221@1|root,COG4191@1|root,COG3221@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RNNF@1236|Gammaproteobacteria,1XUU5@135623|Vibrionales 135623|Vibrionales T ABC transporter, phosphonate, periplasmic substrate-binding protein - - 2.7.13.3 ko:K13040 ko02020,map02020 M00514 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,Phosphonate-bd k141_33401_2 1116375.VEJY3_10460 2.89e-124 356.0 COG4566@1|root,COG4566@2|Bacteria,1N6WR@1224|Proteobacteria,1S0TV@1236|Gammaproteobacteria,1XV10@135623|Vibrionales 135623|Vibrionales K helix_turn_helix, Lux Regulon - - - ko:K13041 ko02020,map02020 M00514 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg k141_33401_3 1116375.VEJY3_10455 1.11e-205 569.0 COG1305@1|root,COG1305@2|Bacteria,1MVMI@1224|Proteobacteria,1SXJJ@1236|Gammaproteobacteria,1XZR7@135623|Vibrionales 135623|Vibrionales E Transglutaminase/protease-like homologues - - - - - - - - - - - - Bact_transglu_N,Transglut_core k141_33401_4 1116375.VEJY3_10450 0.0 1525.0 COG2307@1|root,COG2308@1|root,COG2307@2|Bacteria,COG2308@2|Bacteria,1MX5P@1224|Proteobacteria,1RPDC@1236|Gammaproteobacteria,1Y0IQ@135623|Vibrionales 135623|Vibrionales S Circularly permuted ATP-grasp type 2 - - - - - - - - - - - - Alpha-E,CP_ATPgrasp_2 k141_8486_1 1294265.JCM21738_112 2.26e-38 135.0 COG0142@1|root,COG0142@2|Bacteria,1V1TG@1239|Firmicutes,4HIBX@91061|Bacilli,1ZETD@1386|Bacillus 91061|Bacilli H heptaprenyl diphosphate synthase hepS - 2.5.1.30 ko:K00805 ko00900,ko01110,map00900,map01110 - R09247 RC00279 ko00000,ko00001,ko01000,ko01006 - - - HEPPP_synt_1 k141_8486_2 1294265.JCM21738_113 3.1e-151 426.0 COG0500@1|root,COG2226@2|Bacteria,1TQEA@1239|Firmicutes,4HAR9@91061|Bacilli,1ZB6U@1386|Bacillus 91061|Bacilli H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) menG GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.1.1.163,2.1.1.201 ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116,M00117 R04990,R04993,R06859,R08774,R09736 RC00003,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000 - - - Ubie_methyltran k141_6135_1 42565.FP66_12975 3.48e-110 344.0 COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,1RMDS@1236|Gammaproteobacteria,1XHTN@135619|Oceanospirillales 135619|Oceanospirillales J Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs rne - 3.1.26.12 ko:K08300 ko03018,map03018 M00394 - - ko00000,ko00001,ko00002,ko01000,ko03009,ko03019 - - - RNase_E_G,S1 k141_22739_1 1294265.JCM21738_4751 2.8e-106 309.0 COG5662@1|root,COG5662@2|Bacteria,1V6C7@1239|Firmicutes,4HFTK@91061|Bacilli,1ZE1K@1386|Bacillus 91061|Bacilli K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation rsiW GO:0005575,GO:0016020 - - - - - - - - - - Bactofilin,zf-HC2 k141_7266_1 1444310.JANV01000162_gene1160 4.85e-19 93.6 2BJAU@1|root,32DKR@2|Bacteria,1UX7J@1239|Firmicutes,4IP3A@91061|Bacilli,1ZPBG@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_21579_1 1116375.VEJY3_05600 9.59e-182 513.0 COG3434@1|root,COG3434@2|Bacteria,1MVW1@1224|Proteobacteria,1RS25@1236|Gammaproteobacteria,1XTJ5@135623|Vibrionales 135623|Vibrionales T signal transduction protein containing EAL and modified HD-GYP domains - - - - - - - - - - - - EAL,HDOD k141_21579_2 1116375.VEJY3_05605 4.9e-154 434.0 COG2908@1|root,COG2908@2|Bacteria,1N3U7@1224|Proteobacteria,1RP1X@1236|Gammaproteobacteria,1XSQ8@135623|Vibrionales 135623|Vibrionales S Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxH - 3.6.1.54 ko:K03269 ko00540,ko01100,map00540,map01100 M00060 R04549 RC00002 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Metallophos,Metallophos_2 k141_21579_3 1219077.VAZ01S_070_00160 7.95e-117 334.0 COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,1S222@1236|Gammaproteobacteria,1XVAN@135623|Vibrionales 135623|Vibrionales G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides ppiB - 5.2.1.8 ko:K03768 - - - - ko00000,ko01000,ko03110 - - - Pro_isomerase k141_21579_4 674977.VMC_41500 3.9e-151 434.0 COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,1RP5K@1236|Gammaproteobacteria,1XTZJ@135623|Vibrionales 135623|Vibrionales J Belongs to the class-I aminoacyl-tRNA synthetase family cysS GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 ko:K01883 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_2,tRNA-synt_1e,tRNA-synt_1g k141_31085_1 1116375.VEJY3_02885 1.65e-179 509.0 COG1757@1|root,COG1757@2|Bacteria,1MX0T@1224|Proteobacteria,1RN8E@1236|Gammaproteobacteria,1XSIG@135623|Vibrionales 135623|Vibrionales C Na H antiporter - - - - - - - - - - - - Na_H_antiporter k141_16774_1 243090.RB8885 1.17e-42 156.0 COG3211@1|root,COG3211@2|Bacteria,2IXU8@203682|Planctomycetes 203682|Planctomycetes S Bacterial protein of unknown function (DUF839) - - - ko:K07093 - - - - ko00000 - - - DUF839 k141_2538_1 1116375.VEJY3_07825 7.54e-216 607.0 COG0494@1|root,COG0671@1|root,COG0494@2|Bacteria,COG0671@2|Bacteria,1NCFS@1224|Proteobacteria,1SCXM@1236|Gammaproteobacteria,1XTRI@135623|Vibrionales 135623|Vibrionales IL COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - - - - - - - - - - NUDIX,PAP2 k141_4885_1 218284.CCDN010000002_gene2256 1.58e-188 531.0 COG0477@1|root,COG0477@2|Bacteria,1UIJV@1239|Firmicutes,4ISKN@91061|Bacilli,1ZS6S@1386|Bacillus 91061|Bacilli EGP COG0477 Permeases of the major facilitator superfamily yfkF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - MFS_1,MFS_1_like k141_200_1 218284.CCDN010000001_gene1547 1.41e-103 311.0 COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,4ISRZ@91061|Bacilli,1ZQ9G@1386|Bacillus 91061|Bacilli S Domain of unknown function DUF21 - - - - - - - - - - - - CBS,CorC_HlyC,DUF21 k141_200_2 1117379.BABA_05031 2e-28 111.0 28I6D@1|root,2Z89E@2|Bacteria,1TQNW@1239|Firmicutes,4HB4A@91061|Bacilli,1ZB51@1386|Bacillus 91061|Bacilli S EcsC protein family - - - - - - - - - - - - EcsC k141_1271_2 441769.ABFU01000029_gene1077 6.18e-37 126.0 COG1550@1|root,COG1550@2|Bacteria,1VEHY@1239|Firmicutes,4HNXC@91061|Bacilli,1ZI43@1386|Bacillus 91061|Bacilli S protein conserved in bacteria ylxP - - ko:K09764 - - - - ko00000 - - - DUF503 k141_7268_1 218284.CCDN010000001_gene46 2.24e-84 271.0 COG1198@1|root,COG1198@2|Bacteria,1TNYB@1239|Firmicutes,4H9WW@91061|Bacilli,1ZCBY@1386|Bacillus 91061|Bacilli L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA priA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - ko:K04066 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,ResIII k141_7268_2 218284.CCDN010000001_gene47 6.67e-11 62.8 COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,4HAK8@91061|Bacilli,1ZD3R@1386|Bacillus 91061|Bacilli H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine coaBC - 4.1.1.36,6.3.2.5 ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 - - - DFP,Flavoprotein k141_23882_1 1396.DJ87_5797 3.02e-88 263.0 COG0546@1|root,COG0546@2|Bacteria,1V421@1239|Firmicutes,4HHYH@91061|Bacilli,1ZQ23@1386|Bacillus 91061|Bacilli S Haloacid dehalogenase-like hydrolase - - - - - - - - - - - - HAD_2 k141_31086_2 218284.CCDN010000002_gene2077 3.3e-74 232.0 COG0665@1|root,COG0665@2|Bacteria,1TQTF@1239|Firmicutes,4HA0F@91061|Bacilli,1ZBU6@1386|Bacillus 91061|Bacilli E COG0665 Glycine D-amino acid oxidases (deaminating) yurR GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0044424,GO:0044464,GO:0055114 1.4.5.1 ko:K00285 ko00360,map00360 - R01374,R09493 RC00006,RC00025 ko00000,ko00001,ko01000 - - - DAO k141_20310_1 106370.Francci3_2809 2.31e-51 173.0 COG0640@1|root,COG0640@2|Bacteria,2GJT9@201174|Actinobacteria,4ETFJ@85013|Frankiales 201174|Actinobacteria K Helix-turn-helix domain - - - - - - - - - - - - HTH_20 k141_8488_1 1196322.A370_03188 2.29e-77 258.0 COG3210@1|root,COG3387@1|root,COG3210@2|Bacteria,COG3387@2|Bacteria,1UHGW@1239|Firmicutes,24S1Q@186801|Clostridia 186801|Clostridia U domain, Protein - - - - - - - - - - - - - k141_26331_1 525897.Dbac_3057 4.13e-51 183.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MQ0@68525|delta/epsilon subdivisions,2WISW@28221|Deltaproteobacteria,2MA4J@213115|Desulfovibrionales 28221|Deltaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran k141_28713_1 666686.B1NLA3E_15030 3.92e-32 117.0 COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,4HI6P@91061|Bacilli,1ZPVW@1386|Bacillus 91061|Bacilli CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c resA - - - - - - - - - - - AhpC-TSA k141_28713_2 1294265.JCM21738_49 3.82e-90 278.0 COG1333@1|root,COG1333@2|Bacteria,1TQ6C@1239|Firmicutes,4HAFD@91061|Bacilli,1ZBB3@1386|Bacillus 91061|Bacilli O COG1333 ResB protein required for cytochrome c biosynthesis resB - - ko:K07399 - - - - ko00000 - - - ResB k141_35762_1 1333507.AUTQ01000207_gene1541 7.74e-24 95.9 COG0454@1|root,COG0456@2|Bacteria,1RIU4@1224|Proteobacteria,1S6NR@1236|Gammaproteobacteria,2Q30F@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria K FR47-like protein - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10 k141_35762_3 1042377.AFPJ01000054_gene1689 7.52e-39 131.0 COG3615@1|root,COG3615@2|Bacteria,1QVHF@1224|Proteobacteria,1T2PV@1236|Gammaproteobacteria,46D8A@72275|Alteromonadaceae 1236|Gammaproteobacteria P Protein of unknown function (DUF3565) - - - - - - - - - - - - DUF3565 k141_27452_1 218284.CCDN010000001_gene795 2.5e-14 72.0 COG3330@1|root,COG3330@2|Bacteria,1V2ZT@1239|Firmicutes,4I257@91061|Bacilli,1ZG55@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF4912) - - - ko:K09942 - - - - ko00000 - - - DUF4912 k141_13248_1 218284.CCDN010000006_gene3567 2.24e-61 197.0 COG1090@1|root,COG1090@2|Bacteria,1TSEG@1239|Firmicutes,4HEV9@91061|Bacilli,1ZB7I@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF1731) - - - ko:K07071 - - - - ko00000 - - - DUF1731,Epimerase k141_13248_2 1405.DJ92_5008 1.26e-93 282.0 COG0596@1|root,COG0596@2|Bacteria,1TR6D@1239|Firmicutes,4HFA0@91061|Bacilli,1ZFYE@1386|Bacillus 91061|Bacilli S alpha/beta hydrolase fold - - - - - - - - - - - - Abhydrolase_1 k141_2540_1 1453501.JELR01000002_gene748 1.7e-19 82.4 2EU5W@1|root,33MNG@2|Bacteria,1NPY2@1224|Proteobacteria,1SI8X@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - ko:K06080 ko02020,map02020 - - - ko00000,ko00001 - - - - k141_26332_1 218284.CCDN010000003_gene2986 8.73e-111 322.0 COG1825@1|root,COG1825@2|Bacteria,1VA38@1239|Firmicutes,4HIMM@91061|Bacilli,1ZDPJ@1386|Bacillus 91061|Bacilli J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ctc GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02897 ko03010,map03010 M00178 - - ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L25p,Ribosomal_TL5_C k141_25066_1 13616.ENSMODP00000003143 1.06e-09 66.2 COG4336@1|root,2QV7A@2759|Eukaryota,39415@33154|Opisthokonta,3BA70@33208|Metazoa,3CZE6@33213|Bilateria,47ZD3@7711|Chordata,496JA@7742|Vertebrata,3JD47@40674|Mammalia,4JZA7@9263|Metatheria 33208|Metazoa S Chromosome 14 open reading frame 159 C14orf159 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006520,GO:0006536,GO:0006807,GO:0008150,GO:0008152,GO:0009064,GO:0009975,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0047820,GO:0070013,GO:0071704,GO:1901564,GO:1901605 4.2.1.48 ko:K22210 ko00471,map00471 - R01583 RC00553 ko00000,ko00001,ko01000 - - - DUF1445,DUF4392 k141_25066_2 1042377.AFPJ01000042_gene1010 4.23e-128 379.0 COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,1RM8U@1236|Gammaproteobacteria,464PJ@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids dadX - 5.1.1.1 ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 - R00401 RC00285 ko00000,ko00001,ko01000,ko01011 - - iEC55989_1330.EC55989_1285,iECIAI39_1322.ECIAI39_1880,iECO103_1326.ECO103_1292,iECO26_1355.ECO26_1703,iECSE_1348.ECSE_1238,iECUMN_1333.ECUMN_1479,iECW_1372.ECW_m1275,iEKO11_1354.EKO11_2666,iEcE24377_1341.EcE24377A_1335,iWFL_1372.ECW_m1275,iYL1228.KPN_02308 Ala_racemase_C,Ala_racemase_N k141_25066_3 754476.Q7A_2737 5.32e-87 265.0 COG1540@1|root,COG1540@2|Bacteria,1MUYV@1224|Proteobacteria,1RSCZ@1236|Gammaproteobacteria,460R2@72273|Thiotrichales 72273|Thiotrichales S Belongs to the UPF0271 (lamB) family - - - ko:K07160 - - - - ko00000 - - - LamB_YcsF k141_6137_1 218284.CCDN010000004_gene3153 3.43e-45 161.0 COG0189@1|root,COG0189@2|Bacteria,1V1EV@1239|Firmicutes,4HFNI@91061|Bacilli,1ZBM5@1386|Bacillus 91061|Bacilli HJ YheC/D like ATP-grasp - - - - - - - - - - - - ATPgrasp_YheCD k141_27465_1 326423.RBAM_008390 0.000172 50.1 COG5434@1|root,COG5434@2|Bacteria,1TSDM@1239|Firmicutes,4HF01@91061|Bacilli 91061|Bacilli M COG5434 Endopolygalacturonase yobO - - - - - - - - - - - Pectate_lyase_3,Peptidase_G2 k141_7291_1 1123236.KB899377_gene155 1.79e-98 307.0 COG2183@1|root,COG2183@2|Bacteria,1MUA7@1224|Proteobacteria,1RMNH@1236|Gammaproteobacteria,464NC@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG2183 Transcriptional accessory protein yhgF GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0044424,GO:0044444,GO:0044464,GO:0050896 - ko:K06959 - - - - ko00000 - - - HHH_3,S1,Tex_N,Tex_YqgF k141_14449_1 1300345.LF41_2562 2.9e-78 243.0 COG0491@1|root,COG0491@2|Bacteria,1P5NJ@1224|Proteobacteria,1S1CZ@1236|Gammaproteobacteria,1X6Q6@135614|Xanthomonadales 135614|Xanthomonadales S Metallo-beta-lactamase superfamily - - 3.5.2.6 ko:K17837 ko01501,map01501 - R06363 RC01499 ko00000,ko00001,ko01000 - - - Lactamase_B k141_226_2 218284.CCDN010000001_gene513 8.11e-215 595.0 COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,4HAPN@91061|Bacilli,1ZB3D@1386|Bacillus 91061|Bacilli F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis pfkA GO:0003674,GO:0003824,GO:0003872,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008443,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019200,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046835,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061615,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.11 ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 M00001,M00345 R00756,R03236,R03237,R03238,R03239,R04779 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 - - iYO844.BSU29190 PFK k141_226_3 1196031.ALEG01000064_gene3609 1.34e-09 57.8 COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,4H9VY@91061|Bacilli,1ZCDT@1386|Bacillus 91061|Bacilli G Belongs to the pyruvate kinase family pyk GO:0001871,GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0030246,GO:0030247,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:2001065 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - PEP-utilizers,PK,PK_C k141_35779_1 1453501.JELR01000002_gene925 6.4e-30 115.0 COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,1RMUG@1236|Gammaproteobacteria,464H8@72275|Alteromonadaceae 1236|Gammaproteobacteria O HflC and HflK could encode or regulate a protease hflK GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009408,GO:0009628,GO:0009897,GO:0009986,GO:0016020,GO:0016021,GO:0016787,GO:0019538,GO:0031224,GO:0031226,GO:0031233,GO:0032991,GO:0043086,GO:0043170,GO:0044092,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0050790,GO:0050896,GO:0065007,GO:0065009,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0098796,GO:0140096,GO:1901564 - ko:K04088 - M00742 - - ko00000,ko00002,ko01000 - - - Band_7,HflK_N k141_36972_1 1116375.VEJY3_20416 1.59e-230 659.0 COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,1RMYC@1236|Gammaproteobacteria,1XW5H@135623|Vibrionales 135623|Vibrionales P Cation transporting ATPase, C-terminus - - - - - - - - - - - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase k141_26352_1 1453501.JELR01000001_gene2829 3.77e-94 290.0 COG2272@1|root,COG2272@2|Bacteria,1MVQZ@1224|Proteobacteria,1RPFW@1236|Gammaproteobacteria,465DX@72275|Alteromonadaceae 1236|Gammaproteobacteria I Carboxylesterase family estA1 - - ko:K03929 - - - - ko00000,ko01000 - CE10 - COesterase k141_19151_1 997296.PB1_10097 1.99e-47 166.0 29H5Q@1|root,30439@2|Bacteria,1V63Q@1239|Firmicutes,4HHR2@91061|Bacilli,1ZE9T@1386|Bacillus 91061|Bacilli S Nuclease-related domain - - - - - - - - - - - - NERD k141_20321_1 218284.CCDN010000001_gene1482 2.07e-147 425.0 COG2233@1|root,COG2233@2|Bacteria,1TNZZ@1239|Firmicutes,4HBAM@91061|Bacilli,1ZAUK@1386|Bacillus 91061|Bacilli F xanthine pbuX GO:0003674,GO:0005215,GO:0005345,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006863,GO:0008150,GO:0015205,GO:0015851,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0042906,GO:0042907,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072530,GO:1904823 - ko:K16169 - - - - ko00000,ko02000 2.A.40.3.1 - - Xan_ur_permease k141_20321_2 218284.CCDN010000001_gene1483 1.92e-17 80.9 COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HACS@91061|Bacilli,1ZATG@1386|Bacillus 91061|Bacilli IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - 6.2.1.3 ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding,AMP-binding_C k141_27466_1 240016.ABIZ01000001_gene1413 1.68e-61 203.0 COG3174@1|root,COG3174@2|Bacteria,46VTJ@74201|Verrucomicrobia 74201|Verrucomicrobia S Domain of unknown function (DUF4010) - - - - - - - - - - - - DUF4010,MgtC k141_6168_1 218284.CCDN010000005_gene3243 1.57e-104 307.0 COG1562@1|root,COG1562@2|Bacteria,1TQHF@1239|Firmicutes,4HA1A@91061|Bacilli,1ZCIV@1386|Bacillus 91061|Bacilli I phytoene crtM - 2.5.1.32,2.5.1.99 ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 M00097 R02065,R04218,R07270,R10177 RC00362,RC01101,RC02869 ko00000,ko00001,ko00002,ko01000,ko01006 - - - SQS_PSY k141_25081_1 1116375.VEJY3_19146 3.27e-241 672.0 COG2199@1|root,COG2199@2|Bacteria,1P3SE@1224|Proteobacteria,1SSZV@1236|Gammaproteobacteria,1XV3A@135623|Vibrionales 135623|Vibrionales T diguanylate cyclase - - - - - - - - - - - - GGDEF k141_25081_2 1116375.VEJY3_19141 9.19e-127 363.0 COG2197@1|root,COG2197@2|Bacteria,1Q0DT@1224|Proteobacteria,1RY1Z@1236|Gammaproteobacteria,1XVXJ@135623|Vibrionales 135623|Vibrionales K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - ko:K07688,ko:K07690 ko02020,ko05133,map02020,map05133 M00477,M00697 - - ko00000,ko00001,ko00002,ko01504,ko02022 - - - GerE,Response_reg k141_25081_3 1116375.VEJY3_19136 6.71e-216 603.0 COG2200@1|root,COG2200@2|Bacteria,1N299@1224|Proteobacteria,1S1MD@1236|Gammaproteobacteria,1XTY5@135623|Vibrionales 135623|Vibrionales T COG0784 FOG CheY-like receiver - - - - - - - - - - - - EAL,Response_reg k141_25081_4 1116375.VEJY3_19131 1.86e-297 850.0 COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1RPRH@1236|Gammaproteobacteria,1XSQZ@135623|Vibrionales 135623|Vibrionales T COG0642 Signal transduction histidine kinase - - 2.7.13.3 ko:K07679 ko02020,ko05133,map02020,map05133 M00477 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,Hpt,Response_reg,SBP_bac_3 k141_7293_1 1294265.JCM21738_2124 1.8e-46 154.0 COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,4HAAP@91061|Bacilli,1ZM19@1386|Bacillus 91061|Bacilli S Metallo-beta-lactamase superfamily - - - ko:K12574 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - Lactamase_B,RMMBL k141_2565_2 218284.CCDN010000001_gene1249 9.83e-194 542.0 COG0707@1|root,COG0707@2|Bacteria,1TQFT@1239|Firmicutes,4HBAQ@91061|Bacilli,1ZBA5@1386|Bacillus 91061|Bacilli M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) murG - 2.4.1.227 ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 - R05032,R05662 RC00005,RC00049 ko00000,ko00001,ko01000,ko01011 - GT28 - Glyco_tran_28_C,Glyco_transf_28 k141_9652_2 674977.VMC_31980 3.71e-298 816.0 COG2704@1|root,COG2704@2|Bacteria,1MVHH@1224|Proteobacteria,1RPTE@1236|Gammaproteobacteria,1XT7X@135623|Vibrionales 135623|Vibrionales S Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane dcuB - - ko:K07792 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.13.1 - - DcuA_DcuB k141_25082_2 1479235.KK366039_gene2989 1.37e-116 345.0 COG0842@1|root,COG0842@2|Bacteria,1PM1H@1224|Proteobacteria,1RUN8@1236|Gammaproteobacteria,1XQN3@135619|Oceanospirillales 135619|Oceanospirillales V ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 k141_20322_1 1294265.JCM21738_3399 6.29e-11 58.5 2B33U@1|root,31VRG@2|Bacteria,1V7D5@1239|Firmicutes,4HIPZ@91061|Bacilli,1ZGYF@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3905) - - - - - - - - - - - - DUF3905 k141_20322_2 1307436.PBF_04160 1.19e-17 75.1 29S1D@1|root,30D5U@2|Bacteria,1UAW6@1239|Firmicutes,4IM8Z@91061|Bacilli,1ZJHQ@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_20322_3 1196031.ALEG01000039_gene1381 3.78e-10 55.8 2BFYC@1|root,329U5@2|Bacteria,1UC7F@1239|Firmicutes,4INPW@91061|Bacilli,1ZNS4@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_460_1 234267.Acid_0447 1.15e-31 120.0 COG2159@1|root,COG2159@2|Bacteria,3Y7DZ@57723|Acidobacteria 57723|Acidobacteria S PFAM amidohydrolase - - - - - - - - - - - - Amidohydro_2 k141_460_2 1177179.A11A3_08245 2.02e-176 511.0 COG3515@1|root,COG3515@2|Bacteria,1NRMK@1224|Proteobacteria,1SKMK@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein conserved in bacteria - - - - - - - - - - - - - k141_460_3 1120956.JHZK01000025_gene1978 1.45e-68 243.0 COG0668@1|root,COG0668@2|Bacteria,1MXD2@1224|Proteobacteria,2TV7R@28211|Alphaproteobacteria,1JQ2B@119043|Rhodobiaceae 28211|Alphaproteobacteria M Mechanosensitive ion channel - - - ko:K16052,ko:K22044 - - - - ko00000,ko02000 1.A.23.3,1.A.23.4 - - MS_channel k141_460_5 1117319.PSPO_16083 6.08e-152 437.0 COG1446@1|root,COG1446@2|Bacteria,1MWFC@1224|Proteobacteria,1RNUR@1236|Gammaproteobacteria,2Q19T@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria E COG1446 Asparaginase iaaA - 3.4.19.5,3.5.1.1 ko:K01424,ko:K13051 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 - R00485 RC00010,RC02798 ko00000,ko00001,ko01000,ko01002 - - - Asparaginase_2 k141_15819_1 1453501.JELR01000002_gene329 1.37e-41 151.0 COG3063@1|root,COG3063@2|Bacteria,1R0M2@1224|Proteobacteria,1T4K4@1236|Gammaproteobacteria,46DCA@72275|Alteromonadaceae 1236|Gammaproteobacteria NU Tetratricopeptide repeat - - - - - - - - - - - - TPR_16,TPR_8,Transglut_core k141_1504_1 1382356.JQMP01000003_gene2558 9.73e-20 90.5 COG0566@1|root,COG0566@2|Bacteria,2G6MC@200795|Chloroflexi,27YC9@189775|Thermomicrobia 189775|Thermomicrobia J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family - - - ko:K03437 - - - - ko00000,ko03016 - - - SpoU_methylase,SpoU_sub_bind k141_4020_1 1238184.CM001792_gene3364 1.87e-67 211.0 COG1280@1|root,COG1280@2|Bacteria,1V1Q5@1239|Firmicutes,4HFVQ@91061|Bacilli,23KDR@182709|Oceanobacillus 91061|Bacilli E LysE type translocator ycgF GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015174,GO:0015181,GO:0015318,GO:0015711,GO:0015802,GO:0015807,GO:0015809,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0034220,GO:0042221,GO:0042493,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902023,GO:1903825,GO:1903826,GO:1905039,GO:1990822 - - - - - - - - - - LysE k141_9887_3 279010.BL00973 1.53e-30 111.0 29VDC@1|root,30GU1@2|Bacteria,1TXWR@1239|Firmicutes,4I6ZD@91061|Bacilli,1ZPFY@1386|Bacillus 91061|Bacilli S Phage head-tail joining protein - - - - - - - - - - - - Phage_H_T_join k141_9887_4 1033740.CAEW01000026_gene533 3.92e-12 64.3 2EK8A@1|root,33DYN@2|Bacteria,1VKUA@1239|Firmicutes,4HSSM@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - Phage_connect_1 k141_14591_2 1131730.BAVI_23719 4.52e-109 328.0 COG1066@1|root,COG1066@2|Bacteria,1TQ7Y@1239|Firmicutes,4H9YC@91061|Bacilli,1ZB8H@1386|Bacillus 91061|Bacilli O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function radA - - ko:K04485 - - - - ko00000,ko03400 - - - AAA_25,ATPase,ChlI k141_27604_1 223926.28808378 5.21e-17 76.3 COG2188@1|root,COG2188@2|Bacteria,1R4PN@1224|Proteobacteria,1RQ87@1236|Gammaproteobacteria,1XT3H@135623|Vibrionales 135623|Vibrionales K COG2188 Transcriptional regulators phnR - - - - - - - - - - - GntR,UTRA k141_19355_2 218284.CCDN010000004_gene3141 3.55e-127 374.0 COG0114@1|root,COG0114@2|Bacteria,1UHPH@1239|Firmicutes,4HA6P@91061|Bacilli,1ZS23@1386|Bacillus 91061|Bacilli C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate fumC GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 M00009,M00011,M00173,M00376 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS09430 FumaraseC_C,Lyase_1 k141_33655_1 218284.CCDN010000001_gene1304 3.48e-65 212.0 COG1292@1|root,COG1292@2|Bacteria,1TRS6@1239|Firmicutes,4HA7U@91061|Bacilli,1ZBRN@1386|Bacillus 91061|Bacilli M Belongs to the BCCT transporter (TC 2.A.15) family - - - ko:K05020 - - - - ko00000,ko02000 2.A.15.1.1,2.A.15.1.11 - - BCCT k141_9888_1 218284.CCDN010000002_gene2750 1.25e-90 274.0 COG1173@1|root,COG1173@2|Bacteria,1V21B@1239|Firmicutes,4HJ5Y@91061|Bacilli,1ZFPK@1386|Bacillus 91061|Bacilli EP ABC transporter (permease) - - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 k141_8714_2 324057.Pjdr2_2896 1.5e-11 62.8 COG0500@1|root,COG2226@2|Bacteria,1UYID@1239|Firmicutes,4HAJE@91061|Bacilli,26UBK@186822|Paenibacillaceae 91061|Bacilli Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_25 k141_23013_1 1042377.AFPJ01000043_gene833 3.21e-73 234.0 COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,1RQJ9@1236|Gammaproteobacteria,466HH@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K03585 ko01501,ko01503,map01501,map01503 M00646,M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,8.A.1.6 - - HlyD_D23 k141_18241_1 218284.CCDN010000001_gene1445 7.28e-50 166.0 COG0819@1|root,COG0819@2|Bacteria,1TPK0@1239|Firmicutes,4HCPF@91061|Bacilli,1ZQWS@1386|Bacillus 91061|Bacilli K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway tenA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 3.5.99.2 ko:K03707 ko00730,ko01100,map00730,map01100 - R02133,R09993 RC00224,RC00652,RC02832 ko00000,ko00001,ko01000,ko03000 - - - TENA_THI-4 k141_18241_2 491915.Aflv_2319 2.95e-34 122.0 COG4721@1|root,COG4721@2|Bacteria,1UZIH@1239|Firmicutes,4HG48@91061|Bacilli,21V3X@150247|Anoxybacillus 91061|Bacilli S ABC-type cobalt transport system, permease component ykoE - - ko:K16925 - M00582 - - ko00000,ko00002,ko02000 3.A.1.30 - - ABC_cobalt k141_32354_1 1294265.JCM21738_578 4.3e-06 47.4 COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,4HBX7@91061|Bacilli,1ZBN6@1386|Bacillus 91061|Bacilli KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance relA GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5 ko:K00951 ko00230,map00230 - R00429 RC00002,RC00078 ko00000,ko00001,ko01000 - - iYO844.BSU27600 ACT_4,HD_4,RelA_SpoT,TGS k141_32354_2 935836.JAEL01000008_gene3946 2.94e-159 452.0 28I0M@1|root,2Z85B@2|Bacteria,1TTBC@1239|Firmicutes,4HENN@91061|Bacilli,1ZCDZ@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3231) - - - - - - - - - - - - DUF3231 k141_33656_1 1453501.JELR01000001_gene2612 2.46e-98 301.0 COG2198@1|root,COG2198@2|Bacteria,1QY43@1224|Proteobacteria,1S0ZB@1236|Gammaproteobacteria,4641V@72275|Alteromonadaceae 1236|Gammaproteobacteria T Histidine kinase fimL - - - - - - - - - - - Hpt k141_14592_1 218284.CCDN010000007_gene3855 5.7e-105 307.0 COG0745@1|root,COG0745@2|Bacteria,1TR32@1239|Firmicutes,4HAUJ@91061|Bacilli,1ZCP0@1386|Bacillus 91061|Bacilli T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain graR - - ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 M00469,M00725,M00726,M00730,M00733,M00738 - - ko00000,ko00001,ko00002,ko01504,ko02022 - - - Response_reg,Trans_reg_C k141_35958_2 218284.CCDN010000002_gene1996 1.8e-170 484.0 COG1470@1|root,COG1470@2|Bacteria,1TRGE@1239|Firmicutes,4HBPI@91061|Bacilli,1ZB6W@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3048) C-terminal domain yerB - - - - - - - - - - - DUF3048,DUF3048_C k141_35958_3 1243664.CAVL020000050_gene4699 4.32e-59 183.0 COG4496@1|root,COG4496@2|Bacteria,1VA04@1239|Firmicutes,4HKS8@91061|Bacilli,1ZH87@1386|Bacillus 91061|Bacilli S protein conserved in bacteria yerC - - - - - - - - - - - Trp_repressor k141_462_1 218284.CCDN010000001_gene1870 9.99e-157 461.0 COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,4H9WA@91061|Bacilli,1ZANX@1386|Bacillus 91061|Bacilli D Belongs to the FtsK SpoIIIE SftA family ftsK GO:0000003,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma k141_37132_1 1453501.JELR01000001_gene3251 6.22e-109 325.0 COG0584@1|root,COG0584@2|Bacteria,1MVWZ@1224|Proteobacteria,1RRBP@1236|Gammaproteobacteria,464IE@72275|Alteromonadaceae 1236|Gammaproteobacteria C Glycerophosphoryl diester phosphodiesterase family glpQ GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0008081,GO:0008889,GO:0009279,GO:0016020,GO:0016787,GO:0016788,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0042578,GO:0042597,GO:0043167,GO:0043169,GO:0044462,GO:0044464,GO:0046872,GO:0071944 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - iECNA114_1301.ECNA114_2331,iECSF_1327.ECSF_2119 GDPD k141_11075_1 1042377.AFPJ01000043_gene949 1.57e-62 201.0 COG1087@1|root,COG1087@2|Bacteria,1MUHI@1224|Proteobacteria,1RMTU@1236|Gammaproteobacteria,464WV@72275|Alteromonadaceae 1236|Gammaproteobacteria M UDP-glucose 4-epimerase galE - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase,GDP_Man_Dehyd k141_27605_1 1132442.KB889752_gene2234 1.54e-37 135.0 COG0491@1|root,COG0491@2|Bacteria,1V6FA@1239|Firmicutes,4HHRQ@91061|Bacilli,1ZC72@1386|Bacillus 91061|Bacilli S COG0491 Zn-dependent hydrolases, including glyoxylases yqgX - 3.1.2.6 ko:K01069 ko00620,map00620 - R01736 RC00004,RC00137 ko00000,ko00001,ko01000 - - - Lactamase_B k141_29988_2 1196324.A374_08984 1.38e-88 276.0 COG1961@1|root,COG1961@2|Bacteria,1TPUG@1239|Firmicutes,4HB3H@91061|Bacilli 91061|Bacilli L COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - - - - - - - - - - Recombinase,Resolvase,Zn_ribbon_recom k141_19357_1 36809.MAB_1325c 4.13e-62 212.0 COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,2GK8E@201174|Actinobacteria,233NX@1762|Mycobacteriaceae 201174|Actinobacteria C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family fadH - 1.3.1.34 ko:K00219 - - - - ko00000,ko01000 - - - Oxidored_FMN,Pyr_redox_2 k141_31272_1 1385514.N782_20140 4.09e-18 80.5 COG3650@1|root,COG3650@2|Bacteria,1V96I@1239|Firmicutes,4HNEA@91061|Bacilli,2YBM7@289201|Pontibacillus 91061|Bacilli S response to hydrogen peroxide - - - - - - - - - - - - - k141_31272_2 218284.CCDN010000001_gene1665 4.4e-45 150.0 2B0T9@1|root,31T5P@2|Bacteria,1V9AV@1239|Firmicutes,4HM11@91061|Bacilli,1ZI0C@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - Nuc_deoxyrib_tr k141_23015_1 218284.CCDN010000006_gene3528 3.97e-99 301.0 COG0619@1|root,COG0619@2|Bacteria,1VBW7@1239|Firmicutes,4HB6S@91061|Bacilli,1ZS19@1386|Bacillus 91061|Bacilli P Spore gernimation protein GerA - - - - - - - - - - - - GerA k141_7452_1 1283284.AZUK01000001_gene1432 3.82e-22 98.2 COG0715@1|root,COG2199@1|root,COG0715@2|Bacteria,COG3706@2|Bacteria,1QUXS@1224|Proteobacteria,1T258@1236|Gammaproteobacteria,1Y6PW@135624|Aeromonadales 135624|Aeromonadales PT diguanylate cyclase - - - - - - - - - - - - GGDEF,NMT1,PAS_3 k141_7452_2 796620.VIBC2010_07254 6.22e-91 281.0 COG5039@1|root,COG5039@2|Bacteria,1RBQD@1224|Proteobacteria,1S3JQ@1236|Gammaproteobacteria,1XYJJ@135623|Vibrionales 135623|Vibrionales GM Polysaccharide pyruvyl transferase - - - ko:K19431 - - - - ko00000,ko01000 - - - PS_pyruv_trans k141_7452_3 398579.Spea_1407 6.05e-126 378.0 COG1887@1|root,COG1887@2|Bacteria,1RC5R@1224|Proteobacteria,1SNH0@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC - - - - - - - - - - - - Glyphos_transf k141_7452_4 701176.VIBRN418_00891 6.45e-119 347.0 COG1213@1|root,COG1213@2|Bacteria,1RB54@1224|Proteobacteria,1S2SE@1236|Gammaproteobacteria 1236|Gammaproteobacteria M MobA-like NTP transferase domain - - - - - - - - - - - - NTP_transf_3 k141_7452_5 1172562.HCN_1066 1.24e-15 79.3 COG2071@1|root,COG2071@2|Bacteria,1MZVA@1224|Proteobacteria,42R3F@68525|delta/epsilon subdivisions 1224|Proteobacteria S glutamine amidotransferase - - - ko:K07010 - - - - ko00000,ko01002 - - - Peptidase_C26 k141_7452_6 701176.VIBRN418_00901 0.0 1170.0 COG0574@1|root,COG1213@1|root,COG0574@2|Bacteria,COG1213@2|Bacteria,1MUSN@1224|Proteobacteria,1RS5A@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - 2.7.3.13 ko:K22424 - - - - ko00000,ko01000 - - - PEP-utilizers,PPDK_N k141_7452_8 1114964.L485_07965 2.45e-40 144.0 COG0457@1|root,COG0457@2|Bacteria,1QWT6@1224|Proteobacteria,2TXSR@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - - k141_7452_9 1116375.VEJY3_08125 3.05e-226 635.0 28MGP@1|root,2ZATU@2|Bacteria,1QME8@1224|Proteobacteria,1T5MA@1236|Gammaproteobacteria,1Y3CB@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_7452_11 1116375.VEJY3_08120 2.02e-193 540.0 COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,1RPCE@1236|Gammaproteobacteria,1XSFK@135623|Vibrionales 135623|Vibrionales M COG0463 Glycosyltransferases involved in cell wall biogenesis - - - ko:K20534 - - - - ko00000,ko01000,ko01005,ko02000 4.D.2.1.9 GT2 - Glycos_transf_2 k141_7452_12 1454202.PPBDW_10036___1 2.79e-199 559.0 COG5527@1|root,COG5527@2|Bacteria,1NWTT@1224|Proteobacteria,1SNXZ@1236|Gammaproteobacteria,1XV2W@135623|Vibrionales 135623|Vibrionales L Initiator Replication protein repA - - - - - - - - - - - Rep_3 k141_20510_1 1046625.AFQY01000003_gene2535 5.38e-156 452.0 COG0641@1|root,COG0641@2|Bacteria,1NG2E@1224|Proteobacteria,1RQK4@1236|Gammaproteobacteria,3NQFG@468|Moraxellaceae 1236|Gammaproteobacteria C Radical SAM superfamily - - - - - - - - - - - - Fer4_12,Radical_SAM k141_12361_1 218284.CCDN010000005_gene3414 4.3e-100 291.0 COG1267@1|root,COG1267@2|Bacteria,1V3I0@1239|Firmicutes,4HH4Y@91061|Bacilli,1ZFQE@1386|Bacillus 91061|Bacilli I COG1267 Phosphatidylglycerophosphatase A and related proteins yutG - 3.1.3.27 ko:K01095 ko00564,ko01100,map00564,map01100 - R02029 RC00017 ko00000,ko00001,ko01000 - - - PgpA k141_34809_1 1453501.JELR01000001_gene2381 2.11e-10 58.9 COG2165@1|root,COG2165@2|Bacteria,1N737@1224|Proteobacteria,1SC8X@1236|Gammaproteobacteria,468WY@72275|Alteromonadaceae 1236|Gammaproteobacteria NU General secretion pathway protein I gspI GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - ko:K02458 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - N_methyl,T2SSI k141_34809_2 1453501.JELR01000001_gene2382 5.46e-55 180.0 COG2165@1|root,COG2165@2|Bacteria 2|Bacteria NU general secretion pathway protein gspH - - ko:K02457,ko:K02650 ko02020,ko03070,ko05111,map02020,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 - - GspH,N_methyl k141_34809_3 1453501.JELR01000001_gene2383 1.13e-85 253.0 COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,1S3VS@1236|Gammaproteobacteria,467BP@72275|Alteromonadaceae 1236|Gammaproteobacteria U COG2165 Type II secretory pathway, pseudopilin PulG gspG - - ko:K02456 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - N_methyl,T2SSG k141_34809_4 1453501.JELR01000001_gene2384 2.69e-221 618.0 COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RQ86@1236|Gammaproteobacteria,465B4@72275|Alteromonadaceae 1236|Gammaproteobacteria U General secretion pathway protein F gspF - - ko:K02455 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSF k141_34809_6 1279017.AQYJ01000025_gene580 0.0 998.0 COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,1RPJS@1236|Gammaproteobacteria,4658F@72275|Alteromonadaceae 1236|Gammaproteobacteria NU COG1450 Type II secretory pathway, component PulD gspD - - ko:K02453 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - SPOR,Secretin,Secretin_N k141_34809_7 1453501.JELR01000001_gene2387 7.57e-74 230.0 COG3031@1|root,COG3031@2|Bacteria,1NHQ4@1224|Proteobacteria,1SHIQ@1236|Gammaproteobacteria,46C8P@72275|Alteromonadaceae 1236|Gammaproteobacteria U Type II secretion system protein C - - - ko:K02452 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSC k141_34809_8 1279017.AQYJ01000025_gene582 6.92e-192 536.0 COG2025@1|root,COG2025@2|Bacteria,1MUFI@1224|Proteobacteria,1RMK7@1236|Gammaproteobacteria,465NP@72275|Alteromonadaceae 1236|Gammaproteobacteria C electron transfer flavoprotein, alpha subunit etfA - - ko:K03522 - - - - ko00000,ko04147 - - - ETF,ETF_alpha k141_34809_9 1279017.AQYJ01000025_gene583 4.32e-156 440.0 COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,1RN6F@1236|Gammaproteobacteria,464UJ@72275|Alteromonadaceae 1236|Gammaproteobacteria C Electron transfer flavoprotein etfB - - ko:K03521 - - - - ko00000 - - - ETF k141_34809_10 1279017.AQYJ01000025_gene584 0.0 1031.0 COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria,1MVU6@1224|Proteobacteria,1RNY5@1236|Gammaproteobacteria,464BX@72275|Alteromonadaceae 1236|Gammaproteobacteria C Electron transfer flavoprotein-ubiquinone oxidoreductase etfD - 1.5.5.1 ko:K00311 - - - - ko00000,ko01000 - - - ETF_QO,FAD_binding_2,NAD_binding_8,Thi4 k141_34809_11 1217714.F975_01950 2.3e-07 57.0 COG1335@1|root,COG1335@2|Bacteria,1RDHA@1224|Proteobacteria,1RYJE@1236|Gammaproteobacteria,3NT4E@468|Moraxellaceae 1236|Gammaproteobacteria Q Isochorismatase family - - - - - - - - - - - - Isochorismatase k141_34809_12 1453501.JELR01000001_gene2391 0.0 1424.0 COG1629@1|root,COG1629@2|Bacteria,1MX4K@1224|Proteobacteria,1RP6B@1236|Gammaproteobacteria,464ZU@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec k141_34809_13 1042377.AFPJ01000007_gene1844 5.25e-310 855.0 COG3291@1|root,COG3291@2|Bacteria,1QU15@1224|Proteobacteria,1T1KN@1236|Gammaproteobacteria,46D2W@72275|Alteromonadaceae 1236|Gammaproteobacteria S Pkd domain containing protein - - - - - - - - - - - - - k141_26732_3 218284.CCDN010000001_gene1202 1.68e-153 436.0 COG1307@1|root,COG1307@2|Bacteria,1TRZ4@1239|Firmicutes,4HBR8@91061|Bacilli,1ZCJP@1386|Bacillus 91061|Bacilli S protein conserved in bacteria degV - - - - - - - - - - - DegV k141_12386_1 218284.CCDN010000001_gene1600 9.48e-54 173.0 2A2R1@1|root,30R3Y@2|Bacteria,1U9MP@1239|Firmicutes,4IJT4@91061|Bacilli,1ZE7Q@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_33696_1 1042377.AFPJ01000032_gene2777 3.61e-97 291.0 COG1808@1|root,COG1808@2|Bacteria,1NMS3@1224|Proteobacteria,1RRTC@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Domain of unknown function (DUF389) - - - - - - - - - - - - DUF389 k141_25362_1 1280001.BAOA01000136_gene1949 3.83e-294 805.0 COG3325@1|root,COG3325@2|Bacteria,1MWAR@1224|Proteobacteria,1RPNS@1236|Gammaproteobacteria,1XT0T@135623|Vibrionales 135623|Vibrionales G COG3325 Chitinase - - - - - - - - - - - - Glyco_hydro_18 k141_30004_1 1294265.JCM21738_276 1.81e-95 283.0 COG0164@1|root,COG0164@2|Bacteria,1V1D6@1239|Firmicutes,4HB7M@91061|Bacilli,1ZB7H@1386|Bacillus 91061|Bacilli L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03470 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_HII k141_26733_1 1453501.JELR01000002_gene428 5.19e-137 402.0 COG4264@1|root,COG4264@2|Bacteria,1NEZU@1224|Proteobacteria,1RN4A@1236|Gammaproteobacteria,469KE@72275|Alteromonadaceae 1236|Gammaproteobacteria Q IucA / IucC family - - - - - - - - - - - - FhuF,IucA_IucC k141_23041_1 1453501.JELR01000002_gene387 3.88e-181 521.0 COG0515@1|root,COG0631@1|root,COG0515@2|Bacteria,COG0631@2|Bacteria,1MV1P@1224|Proteobacteria,1RNQN@1236|Gammaproteobacteria,464NH@72275|Alteromonadaceae 1236|Gammaproteobacteria T Serine threonine protein ppkB - - - - - - - - - - - PP2C_2,Pkinase k141_17023_2 935837.JAEK01000001_gene2157 1.5e-19 84.0 COG1713@1|root,COG1713@2|Bacteria,1V6Y1@1239|Firmicutes,4HHRY@91061|Bacilli,1ZCQJ@1386|Bacillus 91061|Bacilli H HD superfamily hydrolase involved in NAD metabolism yqeK - - - - - - - - - - - HD k141_13564_1 218284.CCDN010000001_gene1809 7.2e-91 269.0 COG0586@1|root,COG0586@2|Bacteria,1V76Y@1239|Firmicutes,4HJKU@91061|Bacilli,1ZFU6@1386|Bacillus 91061|Bacilli S SNARE associated Golgi protein - - - - - - - - - - - - SNARE_assoc k141_13564_2 935837.JAEK01000005_gene4391 6.67e-66 220.0 COG0249@1|root,COG0249@2|Bacteria,1TPRJ@1239|Firmicutes,4HA63@91061|Bacilli,1ZB93@1386|Bacillus 91061|Bacilli L that it carries out the mismatch recognition step. This protein has a weak ATPase activity mutS GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K03555 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V k141_7472_1 1042377.AFPJ01000035_gene2620 4.52e-73 245.0 COG0834@1|root,COG4623@1|root,COG0834@2|Bacteria,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,1RM8W@1236|Gammaproteobacteria,467JF@72275|Alteromonadaceae 1236|Gammaproteobacteria EMT Bacterial periplasmic substrate-binding proteins - GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - ko:K18691 - - - - ko00000,ko01000,ko01011 - - - SBP_bac_3,SLT k141_1526_1 218284.CCDN010000001_gene1822 2.25e-122 362.0 COG1966@1|root,COG1966@2|Bacteria,1TQN8@1239|Firmicutes,4H9SU@91061|Bacilli,1ZC6K@1386|Bacillus 91061|Bacilli T Carbon starvation protein cstA_2 - - - - - - - - - - - CstA,CstA_5TM k141_19399_1 1294265.JCM21738_382 3.91e-125 369.0 COG3845@1|root,COG3845@2|Bacteria,1UYQA@1239|Firmicutes,4HVSH@91061|Bacilli,1ZS12@1386|Bacillus 91061|Bacilli S ABC transporter, ATP-binding protein mglA - 3.6.3.17 ko:K02056,ko:K06400 - M00221 - - ko00000,ko00002,ko01000,ko02000 3.A.1.2 - - ABC_tran k141_19399_2 1294265.JCM21738_383 2.64e-56 182.0 COG4603@1|root,COG4603@2|Bacteria,1TP1F@1239|Firmicutes,4H9VE@91061|Bacilli,1ZCTP@1386|Bacillus 91061|Bacilli S Belongs to the binding-protein-dependent transport system permease family yufP GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015749,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0034219,GO:0044425,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 - ko:K02057 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - BPD_transp_2 k141_5129_1 1279017.AQYJ01000023_gene3110 9.42e-125 363.0 COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,1RPSV@1236|Gammaproteobacteria,465UN@72275|Alteromonadaceae 1236|Gammaproteobacteria F Belongs to the ATCase OTCase family pyrB GO:0003674,GO:0003824,GO:0004070,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 - - iZ_1308.Z5856 OTCace,OTCace_N k141_20531_2 502025.Hoch_2836 7.97e-36 127.0 COG0789@1|root,COG0789@2|Bacteria,1PG5J@1224|Proteobacteria,438N8@68525|delta/epsilon subdivisions,2X9Z3@28221|Deltaproteobacteria,2Z2QY@29|Myxococcales 28221|Deltaproteobacteria K MerR, DNA binding - - - ko:K19591 - M00769 - - ko00000,ko00002,ko01504,ko03000 - - - MerR,MerR-DNA-bind k141_20531_3 1123242.JH636434_gene4078 6.7e-07 55.1 COG0500@1|root,COG2226@2|Bacteria,2IXEP@203682|Planctomycetes 203682|Planctomycetes Q O-methyltransferase - - - - - - - - - - - - Dimerisation2,Methyltransf_2 k141_28925_1 1116375.VEJY3_15876 5.07e-14 70.1 28IGK@1|root,2Z8I1@2|Bacteria,1RAH7@1224|Proteobacteria,1RPTY@1236|Gammaproteobacteria,1XTA2@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_28925_2 223926.28808172 9.59e-59 184.0 COG1725@1|root,COG1725@2|Bacteria,1MZG9@1224|Proteobacteria,1S993@1236|Gammaproteobacteria,1XXF2@135623|Vibrionales 135623|Vibrionales K transcriptional - - - ko:K07979 - - - - ko00000,ko03000 - - - GntR k141_28925_3 223926.28808171 1.21e-150 429.0 COG1131@1|root,COG1131@2|Bacteria,1R3XF@1224|Proteobacteria,1S0MM@1236|Gammaproteobacteria,1XT2W@135623|Vibrionales 135623|Vibrionales V abc transporter atp-binding protein - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_28925_4 674977.VMC_04380 6.04e-116 341.0 2E7DT@1|root,331WV@2|Bacteria,1RBAW@1224|Proteobacteria,1SD4S@1236|Gammaproteobacteria,1XW3G@135623|Vibrionales 135623|Vibrionales - - - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - - k141_14802_1 218284.CCDN010000001_gene716 1.24e-57 183.0 COG1057@1|root,COG1057@2|Bacteria,1V3SK@1239|Firmicutes,4HGXK@91061|Bacilli,1ZFIV@1386|Bacillus 91061|Bacilli H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) nadD GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 ko:K00969 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like k141_14802_2 218284.CCDN010000001_gene717 7.73e-82 246.0 COG1713@1|root,COG1713@2|Bacteria,1V6Y1@1239|Firmicutes,4HHRY@91061|Bacilli,1ZCQJ@1386|Bacillus 91061|Bacilli H HD superfamily hydrolase involved in NAD metabolism yqeK - - - - - - - - - - - HD k141_35145_2 935836.JAEL01000113_gene1399 2.06e-74 224.0 COG0509@1|root,COG0509@2|Bacteria,1V6WV@1239|Firmicutes,4HIMA@91061|Bacilli,1ZGG0@1386|Bacillus 91061|Bacilli E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate gcvH GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 - ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 - - - GCV_H k141_35145_3 1340434.AXVA01000003_gene1984 1.85e-17 77.0 2ET7S@1|root,33KRT@2|Bacteria,1VP54@1239|Firmicutes,4HRRC@91061|Bacilli,1ZIUE@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2553) yusG - - - - - - - - - - - DUF2553 k141_8994_1 218284.CCDN010000001_gene1775 3.81e-128 392.0 COG0419@1|root,COG0419@2|Bacteria,1TPCS@1239|Firmicutes,4H9Q3@91061|Bacilli,1ZAP5@1386|Bacillus 91061|Bacilli L COG0419 ATPase involved in DNA repair sbcC - - ko:K03546 - - - - ko00000,ko03400 - - - AAA_23,AAA_29,SbcCD_C k141_18542_1 218284.CCDN010000007_gene3931 4.97e-38 130.0 29M27@1|root,307ZQ@2|Bacteria,1U2H9@1239|Firmicutes,4IC3S@91061|Bacilli,1ZK2U@1386|Bacillus 91061|Bacilli S Family of unknown function (DUF5327) - - - - - - - - - - - - DUF5327 k141_11434_1 218284.CCDN010000001_gene1905 1.19e-66 206.0 COG1871@1|root,COG1871@2|Bacteria,1V70X@1239|Firmicutes,4HIVG@91061|Bacilli,1ZGE3@1386|Bacillus 91061|Bacilli NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase cheD - 3.5.1.44 ko:K03411 ko02030,map02030 - - - ko00000,ko00001,ko01000,ko02035 - - - CheD k141_11434_2 218284.CCDN010000001_gene1906 1.27e-19 84.0 COG1776@1|root,COG1776@2|Bacteria,1UNKB@1239|Firmicutes,4HB40@91061|Bacilli,1ZDIE@1386|Bacillus 91061|Bacilli NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation cheC GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0050896,GO:0050918 - ko:K03410 ko02030,map02030 - - - ko00000,ko00001,ko02035 - - - CheC,CheX k141_19673_1 1294265.JCM21738_3254 1.14e-44 150.0 COG2271@1|root,COG2271@2|Bacteria,1UYKI@1239|Firmicutes,4H9RN@91061|Bacilli,1ZCB8@1386|Bacillus 91061|Bacilli G Major facilitator superfamily - - - - - - - - - - - - MFS_1 k141_5468_1 1279017.AQYJ01000025_gene630 5.1e-73 244.0 COG0577@1|root,COG0577@2|Bacteria,1PIKV@1224|Proteobacteria,1SYRG@1236|Gammaproteobacteria,466C2@72275|Alteromonadaceae 1236|Gammaproteobacteria V MacB-like periplasmic core domain - - - - - - - - - - - - FtsX,MacB_PCD k141_32557_1 218284.CCDN010000001_gene1222 1.64e-149 422.0 2ESB9@1|root,33JW0@2|Bacteria,1VMVV@1239|Firmicutes,4HSTZ@91061|Bacilli,1ZD8X@1386|Bacillus 91061|Bacilli - - yodN - - - - - - - - - - - - k141_4209_1 1121938.AUDY01000011_gene836 1.25e-84 260.0 COG1902@1|root,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,4HDIY@91061|Bacilli,3NDDY@45667|Halobacillus 91061|Bacilli C NADH:flavin oxidoreductase / NADH oxidase family - - - - - - - - - - - - Oxidored_FMN k141_36153_1 218284.CCDN010000001_gene991 1.73e-52 174.0 COG1703@1|root,COG1703@2|Bacteria,1TQT4@1239|Firmicutes,4H9ZJ@91061|Bacilli,1ZC78@1386|Bacillus 91061|Bacilli E periplasmic protein kinase ArgK and related GTPases of G3E family argK - - ko:K07588 - - - - ko00000,ko01000 - - - ArgK k141_36153_2 218284.CCDN010000001_gene990 4.06e-48 169.0 COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,1TQAD@1239|Firmicutes,4H9QB@91061|Bacilli,1ZCKD@1386|Bacillus 91061|Bacilli I COG1884 Methylmalonyl-CoA mutase, N-terminal domain subunit mutB - 5.4.99.2 ko:K01847 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00373,M00376,M00741 R00833 RC00395 ko00000,ko00001,ko00002,ko01000 - - - B12-binding,MM_CoA_mutase k141_1709_1 1294265.JCM21738_3336 6.65e-229 635.0 COG0067@1|root,COG0069@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,1TQ0B@1239|Firmicutes,4HA4G@91061|Bacilli,1ZM12@1386|Bacillus 91061|Bacilli E Glutamine amidotransferases class-II gltA2 - 1.4.1.13,1.4.1.14 ko:K00265 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - GATase_2,GXGXG,Glu_syn_central,Glu_synthase k141_23281_1 870967.VIS19158_20152 4.03e-206 580.0 COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,1RQ7D@1236|Gammaproteobacteria,1XSW2@135623|Vibrionales 135623|Vibrionales E Asparagine synthetase B asnB - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 k141_23281_2 223926.28805811 8.32e-98 286.0 COG0250@1|root,COG0250@2|Bacteria,1N01W@1224|Proteobacteria,1S91B@1236|Gammaproteobacteria,1XX33@135623|Vibrionales 135623|Vibrionales K Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components rfaH - - ko:K05785 - - - - ko00000,ko03000 - - - NusG k141_30170_1 218284.CCDN010000001_gene160 9.88e-237 660.0 COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,4HAAP@91061|Bacilli,1ZBCD@1386|Bacillus 91061|Bacilli S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay rnjA GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004527,GO:0004532,GO:0004534,GO:0004540,GO:0005488,GO:0005515,GO:0006139,GO:0006364,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008409,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042802,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0090503,GO:0140098,GO:1901360 - ko:K12574 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - Lactamase_B,RMMBL k141_35147_1 42565.FP66_01850 8.16e-56 191.0 COG2199@1|root,COG5000@1|root,COG2199@2|Bacteria,COG5000@2|Bacteria,1RE50@1224|Proteobacteria,1S3P4@1236|Gammaproteobacteria 1236|Gammaproteobacteria T COG2199 FOG GGDEF domain - - - - - - - - - - - - GGDEF,PAS,PAS_3,PAS_4,PAS_8,PAS_9,dCache_1 k141_35147_2 42565.FP66_01855 1.5e-25 102.0 COG1902@1|root,COG1902@2|Bacteria,1MVIX@1224|Proteobacteria,1RMFI@1236|Gammaproteobacteria,1XHEQ@135619|Oceanospirillales 135619|Oceanospirillales C NADH flavin oxidoreductase - - - ko:K10680 ko00633,ko01120,map00633,map01120 - R08014,R08017,R08042 RC00250 ko00000,ko00001,ko01000 - - - Oxidored_FMN k141_29087_2 261726.A2I2Y1_9CAUD 2.96e-55 197.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QHYN@10662|Myoviridae 10662|Myoviridae S amidase activity - - - - - - - - - - - - - k141_18544_1 472759.Nhal_0103 8.77e-75 241.0 COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,1RPPQ@1236|Gammaproteobacteria,1WX09@135613|Chromatiales 135613|Chromatiales P cytochrome c peroxidase - - 1.11.1.5 ko:K00428 - - - - ko00000,ko01000 - - - CCP_MauG k141_31375_2 218284.CCDN010000002_gene1998 2.87e-117 338.0 COG1646@1|root,COG1646@2|Bacteria,1TQQK@1239|Firmicutes,4H9YW@91061|Bacilli,1ZBBT@1386|Bacillus 91061|Bacilli I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales pcrB GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 - ko:K07094 - - - - ko00000,ko01000 - - - PcrB k141_19675_1 279010.BL03332 2.44e-101 303.0 COG3181@1|root,COG3181@2|Bacteria,1V0HH@1239|Firmicutes,4HBWA@91061|Bacilli,1ZB42@1386|Bacillus 91061|Bacilli S Tripartite tricarboxylate transporter family receptor - - - ko:K07795 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.80.1 - - TctC k141_7662_1 218284.CCDN010000005_gene3289 1.21e-116 346.0 COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,4H9TI@91061|Bacilli,1ZBG7@1386|Bacillus 91061|Bacilli I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol cls GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0071704,GO:0071944,GO:0090407,GO:1901576 - ko:K06131 ko00564,ko01100,map00564,map01100 - R07390 RC00017 ko00000,ko00001,ko01000 - - - PLDc_2,PLDc_N k141_13873_2 1453501.JELR01000002_gene1365 1.68e-160 452.0 COG0107@1|root,COG0107@2|Bacteria,1MUS0@1224|Proteobacteria,1RPJQ@1236|Gammaproteobacteria,464M7@72275|Alteromonadaceae 1236|Gammaproteobacteria E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit hisF GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009382,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 - ko:K01663,ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - iECO111_1330.ECO111_2749,iEcolC_1368.EcolC_1617,iYL1228.KPN_02481 His_biosynth k141_8995_1 218284.CCDN010000002_gene2054 2.42e-74 239.0 COG0668@1|root,COG0668@2|Bacteria,1TQXJ@1239|Firmicutes,4HCK2@91061|Bacilli,1ZF3F@1386|Bacillus 91061|Bacilli M Conserved TM helix ygxB - - - - - - - - - - - TM_helix k141_33916_2 1504981.KO116_0725 6.38e-45 150.0 2CNK3@1|root,31TH7@2|Bacteria,1R38H@1224|Proteobacteria,1S7X7@1236|Gammaproteobacteria,1XKY6@135619|Oceanospirillales 135619|Oceanospirillales S Protein of Unknown function (DUF2784) - - - - - - - - - - - - DUF2784 k141_33916_3 946235.CAER01000060_gene3310 3.14e-46 155.0 COG0454@1|root,COG0454@2|Bacteria,1V4EA@1239|Firmicutes,4HHBF@91061|Bacilli 91061|Bacilli K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases ysnE GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031248,GO:0031365,GO:0032991,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564,GO:1902493,GO:1902494,GO:1990234 - ko:K03829 - - - - ko00000,ko01000 - - - Acetyltransf_1 k141_22000_1 1078085.HMPREF1210_00657 5.54e-114 373.0 COG1404@1|root,COG2755@1|root,COG1404@2|Bacteria,COG2755@2|Bacteria,1TPH1@1239|Firmicutes,4HBQH@91061|Bacilli 91061|Bacilli O Belongs to the peptidase S8 family prtS - 3.4.21.110,3.4.21.96 ko:K01361,ko:K08652 - - - - ko00000,ko01000,ko01002,ko03110 - - - FIVAR,Gram_pos_anchor,Inhibitor_I9,PA,Peptidase_S8,SLH,YSIRK_signal,fn3_5 k141_17208_2 1453501.JELR01000001_gene1811 1.85e-172 497.0 COG4325@1|root,COG4325@2|Bacteria,1MXTM@1224|Proteobacteria,1RNYZ@1236|Gammaproteobacteria,466NZ@72275|Alteromonadaceae 1236|Gammaproteobacteria S Predicted membrane protein (DUF2254) - - - - - - - - - - - - DUF2254 k141_17208_4 1279017.AQYJ01000024_gene1175 2.88e-70 213.0 COG0278@1|root,COG0278@2|Bacteria,1MZ4V@1224|Proteobacteria,1S640@1236|Gammaproteobacteria,466TX@72275|Alteromonadaceae 1236|Gammaproteobacteria C Belongs to the glutaredoxin family. Monothiol subfamily grxD - - ko:K07390 - - - - ko00000,ko03029,ko03110 - - - Glutaredoxin,Rhodanese k141_17208_5 1453501.JELR01000001_gene1808 6.17e-225 626.0 COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,1RMV1@1236|Gammaproteobacteria,464Z8@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG4992 Ornithine acetylornithine aminotransferase argD - 2.6.1.11,2.6.1.17 ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R02283,R04475 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 k141_1710_1 796606.BMMGA3_04480 2.68e-88 269.0 COG1744@1|root,COG1744@2|Bacteria,1UY2H@1239|Firmicutes,4HCI5@91061|Bacilli,1ZBN4@1386|Bacillus 91061|Bacilli S Transcriptional activator protein med med - - ko:K05519,ko:K07335 - - - - ko00000,ko03000 - - - Bmp k141_25700_1 1196031.ALEG01000068_gene4949 2.46e-13 68.9 COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TP5X@1239|Firmicutes,4H9KS@91061|Bacilli,1ZE6P@1386|Bacillus 91061|Bacilli G phosphotransferase system ybbF GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563,GO:0090588 2.7.1.211 ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 M00269 R00811 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.1,4.A.1.2.10,4.A.1.2.12,4.A.1.2.9 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC k141_25700_2 218284.CCDN010000005_gene3486 8.95e-116 337.0 COG2188@1|root,COG2188@2|Bacteria,1UYBW@1239|Firmicutes,4HDDG@91061|Bacilli,1ZBS6@1386|Bacillus 91061|Bacilli K transcriptional yvoA - - ko:K03710 - - - - ko00000,ko03000 - - - GntR,UTRA k141_25700_3 218284.CCDN010000005_gene3484 1.94e-156 450.0 COG1820@1|root,COG1820@2|Bacteria,1TPFK@1239|Firmicutes,4HC6C@91061|Bacilli,1ZCM7@1386|Bacillus 91061|Bacilli G Belongs to the metallo-dependent hydrolases superfamily. NagA family nagA GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005515,GO:0006040,GO:0006044,GO:0006046,GO:0008150,GO:0008152,GO:0008448,GO:0009056,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046348,GO:0046872,GO:0046914,GO:0046983,GO:0071704,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901575 3.5.1.25 ko:K01443 ko00520,ko01130,map00520,map01130 - R02059 RC00166,RC00300 ko00000,ko00001,ko01000 - - - Amidohydro_1 k141_5469_1 218284.CCDN010000003_gene2999 1.32e-309 862.0 COG2208@1|root,COG2208@2|Bacteria,1TQ92@1239|Firmicutes,4HB0X@91061|Bacilli,1ZAYZ@1386|Bacillus 91061|Bacilli KT stage II sporulation protein E spoIIE GO:0005575,GO:0005623,GO:0042601,GO:0042763,GO:0044464 3.1.3.16 ko:K06382 - - - - ko00000,ko01000 - - - SpoIIE k141_13874_1 1461580.CCAS010000089_gene4390 5.02e-101 303.0 COG1195@1|root,COG1195@2|Bacteria,1TP9U@1239|Firmicutes,4HA0W@91061|Bacilli,1ZC8V@1386|Bacillus 91061|Bacilli L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP recF GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - ko:K03629 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - SMC_N k141_23283_1 748247.AZKH_2589 9.93e-86 259.0 COG3440@1|root,COG3440@2|Bacteria,1N4JP@1224|Proteobacteria,2VVU0@28216|Betaproteobacteria 28216|Betaproteobacteria V HNH endonuclease - - - ko:K07454 - - - - ko00000 - - - HNH_2 k141_11436_2 406124.ACPC01000049_gene77 1.39e-117 342.0 COG0500@1|root,COG2226@2|Bacteria,1V04P@1239|Firmicutes,4HEGX@91061|Bacilli,1ZCVB@1386|Bacillus 91061|Bacilli Q Nodulation protein S (NodS) - - - - - - - - - - - - Methyltransf_11 k141_30171_2 997296.PB1_01015 1.68e-17 84.3 COG1419@1|root,COG1419@2|Bacteria,1TSP7@1239|Firmicutes,4H9VG@91061|Bacilli,1ZCJ9@1386|Bacillus 91061|Bacilli N Flagellar biosynthesis regulator FlhF flhF GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K02404 - - - - ko00000,ko02035 - - - SRP54 k141_19676_2 1294265.JCM21738_2619 1.81e-86 262.0 COG4989@1|root,COG4989@2|Bacteria,1TQ12@1239|Firmicutes,4HA57@91061|Bacilli,1ZD8D@1386|Bacillus 91061|Bacilli S Oxidoreductase ycsN - - - - - - - - - - - Aldo_ket_red k141_25701_1 1235798.C817_01866 6.8e-10 60.8 COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,249IC@186801|Clostridia,27V28@189330|Dorea 186801|Clostridia K COG COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain resD - - ko:K07775 ko02020,map02020 M00458 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C k141_25701_2 1294265.JCM21738_5146 3.39e-24 101.0 COG2409@1|root,COG2409@2|Bacteria,1TQ7C@1239|Firmicutes,4H9XX@91061|Bacilli,1ZQAJ@1386|Bacillus 91061|Bacilli S MMPL domain protein - - - ko:K06994 - - - - ko00000 - - - MMPL k141_8997_1 1408303.JNJJ01000012_gene1736 3.28e-53 179.0 COG0614@1|root,COG0614@2|Bacteria,1UNE3@1239|Firmicutes,4H9ZX@91061|Bacilli,1ZBS8@1386|Bacillus 91061|Bacilli P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component yvrC - - ko:K02016 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - Peripla_BP_2 k141_32561_1 218284.CCDN010000002_gene2753 2.34e-105 317.0 COG0397@1|root,COG0397@2|Bacteria,1TQXD@1239|Firmicutes,4HBKH@91061|Bacilli,1ZC8A@1386|Bacillus 91061|Bacilli S Belongs to the UPF0061 (SELO) family M1-1044 - - - - - - - - - - - UPF0061 k141_35149_1 1042377.AFPJ01000008_gene2003 1.54e-62 196.0 COG4704@1|root,COG4704@2|Bacteria,1N6RE@1224|Proteobacteria,1SGQS@1236|Gammaproteobacteria,46C17@72275|Alteromonadaceae 1236|Gammaproteobacteria S Uncharacterized protein conserved in bacteria (DUF2141) - - - - - - - - - - - - DUF2141 k141_27000_1 1219076.N646_3510 6.08e-108 336.0 COG3325@1|root,COG3979@1|root,COG3325@2|Bacteria,COG3979@2|Bacteria,1MWAR@1224|Proteobacteria,1RPNS@1236|Gammaproteobacteria,1XT0T@135623|Vibrionales 135623|Vibrionales G COG3325 Chitinase chiA - 3.2.1.14 ko:K01183 ko00520,ko01100,map00520,map01100 - R01206,R02334 RC00467 ko00000,ko00001,ko01000 - GH18 - CBM_5_12,ChitinaseA_N,Glyco_hydro_18,REJ k141_27000_2 1116375.VEJY3_15951 3.36e-187 522.0 COG1073@1|root,COG1073@2|Bacteria,1R4XD@1224|Proteobacteria,1S17K@1236|Gammaproteobacteria,1XUA1@135623|Vibrionales 135623|Vibrionales S hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - - - - - - - - - - Abhydrolase_4,Hydrolase_4 k141_27000_3 1116375.VEJY3_15946 1.64e-127 363.0 COG1309@1|root,COG1309@2|Bacteria,1RGDS@1224|Proteobacteria,1S5Q4@1236|Gammaproteobacteria,1XTUD@135623|Vibrionales 135623|Vibrionales K Transcriptional regulator - - - - - - - - - - - - TetR_N k141_27000_4 223926.28808190 1.12e-197 553.0 COG1835@1|root,COG1835@2|Bacteria,1RJ7V@1224|Proteobacteria,1T109@1236|Gammaproteobacteria,1XTI5@135623|Vibrionales 135623|Vibrionales I protein conserved in bacteria - - - - - - - - - - - - Acyl_transf_3 k141_27000_5 575788.VS_1455 3.64e-273 754.0 COG2801@1|root,COG2801@2|Bacteria,1MWVQ@1224|Proteobacteria,1RN12@1236|Gammaproteobacteria,1XVDW@135623|Vibrionales 135623|Vibrionales L PFAM Integrase catalytic - - - - - - - - - - - - HTH_28,rve k141_7663_1 218284.CCDN010000001_gene659 1.39e-149 434.0 COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,4HAB7@91061|Bacilli,1ZDHC@1386|Bacillus 91061|Bacilli S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid spoVB - - ko:K06409 - - - - ko00000,ko02000 2.A.66.2.14 - - Polysacc_synt,Polysacc_synt_C k141_23284_2 643867.Ftrac_1997 1.92e-100 320.0 COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,4NEDE@976|Bacteroidetes,47K29@768503|Cytophagia 976|Bacteroidetes E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor gcvP - 1.4.4.2 ko:K00281,ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko00002,ko01000 - - - Aminotran_5,GDC-P k141_25702_1 218284.CCDN010000003_gene2963 7.53e-66 204.0 COG0125@1|root,COG0125@2|Bacteria,1V1HE@1239|Firmicutes,4HGWR@91061|Bacilli,1ZBSZ@1386|Bacillus 91061|Bacilli F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis tmk GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 ko:K00943 ko00240,ko01100,map00240,map01100 M00053 R02094,R02098 RC00002 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS02535 Thymidylate_kin k141_5499_1 748280.NH8B_3246 2.78e-27 113.0 COG5495@1|root,COG5495@2|Bacteria,1RBEZ@1224|Proteobacteria,2VS2J@28216|Betaproteobacteria,2KR6Q@206351|Neisseriales 206351|Neisseriales S Rossmann-like domain - - - - - - - - - - - - DUF2520,Rossmann-like k141_5499_2 411473.RUMCAL_01515 1.12e-22 94.4 COG3294@1|root,COG3294@2|Bacteria,1UXSS@1239|Firmicutes,24A8Y@186801|Clostridia,3WGCK@541000|Ruminococcaceae 186801|Clostridia S Psort location Cytoplasmic, score - - - ko:K09163 - - - - ko00000 - - - HD k141_36173_1 218284.CCDN010000001_gene1256 4.3e-113 333.0 COG2378@1|root,COG2378@2|Bacteria,1TSA2@1239|Firmicutes,4HCDN@91061|Bacilli,1ZD8Z@1386|Bacillus 91061|Bacilli K WYL domain - - - - - - - - - - - - WYL k141_9006_1 1121939.L861_13770 3.86e-58 184.0 COG1017@1|root,COG1017@2|Bacteria,1RI9P@1224|Proteobacteria,1S7H7@1236|Gammaproteobacteria,1XMN2@135619|Oceanospirillales 135619|Oceanospirillales C nitric oxide dioxygenase activity - - - - - - - - - - - - - k141_14822_1 1294265.JCM21738_973 1.13e-57 179.0 2E4AM@1|root,32XKC@2|Bacteria,1VE9E@1239|Firmicutes,4HN07@91061|Bacilli,1ZJ0J@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_14822_2 1294265.JCM21738_974 4.68e-74 223.0 2F172@1|root,33U86@2|Bacteria,1VUP5@1239|Firmicutes,4HVPB@91061|Bacilli,1ZH8W@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_14822_3 1294265.JCM21738_975 5.92e-51 164.0 COG0622@1|root,COG0622@2|Bacteria,1V7VB@1239|Firmicutes,4HJ56@91061|Bacilli,1ZF56@1386|Bacillus 91061|Bacilli S Calcineurin-like phosphoesterase superfamily domain - - - ko:K07095 - - - - ko00000 - - - Metallophos_2 k141_30196_2 218284.CCDN010000006_gene3669 8.07e-65 204.0 COG1028@1|root,COG1028@2|Bacteria,1UETI@1239|Firmicutes,4HB6V@91061|Bacilli,1ZB50@1386|Bacillus 91061|Bacilli IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - 1.1.1.69 ko:K00046 - - - - ko00000,ko01000 - - - adh_short,adh_short_C2 k141_19710_1 1294265.JCM21738_4889 2.32e-107 312.0 COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,4HE9H@91061|Bacilli,1ZEYD@1386|Bacillus 91061|Bacilli S Uncharacterised protein, DegV family COG1307 - - - - - - - - - - - - DegV k141_19710_2 1294265.JCM21738_4890 1.42e-56 182.0 COG1073@1|root,COG1073@2|Bacteria,1V5FP@1239|Firmicutes,4HI80@91061|Bacilli,1ZEX6@1386|Bacillus 91061|Bacilli S alpha beta - - - - - - - - - - - - - k141_33941_1 411461.DORFOR_01077 1.02e-10 61.2 COG0192@1|root,COG0192@2|Bacteria,1TPCV@1239|Firmicutes,248QF@186801|Clostridia,27VDA@189330|Dorea 186801|Clostridia H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme metK - 2.5.1.6 ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 M00034,M00035,M00368,M00609 R00177,R04771 RC00021,RC01211 ko00000,ko00001,ko00002,ko01000 - - - S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N k141_33941_2 1294265.JCM21738_2954 7.35e-40 144.0 COG0367@1|root,COG0367@2|Bacteria,1TRPB@1239|Firmicutes,4HAIP@91061|Bacilli,1ZAPW@1386|Bacillus 91061|Bacilli E Asparagine synthase asnB - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 k141_18584_1 396588.Tgr7_2432 1.8e-29 107.0 COG1343@1|root,COG1343@2|Bacteria,1N27I@1224|Proteobacteria,1S9TQ@1236|Gammaproteobacteria,1WZ4I@135613|Chromatiales 135613|Chromatiales L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette - - - ko:K09951 - - - - ko00000,ko02048 - - - CRISPR_Cas2 k141_770_1 218284.CCDN010000002_gene2121 2.81e-39 143.0 COG0119@1|root,COG0119@2|Bacteria,1TP4Y@1239|Firmicutes,4HA6E@91061|Bacilli,1ZC5T@1386|Bacillus 91061|Bacilli E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) leuA - 2.3.3.13 ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 M00432 R01213 RC00004,RC00470,RC02754 br01601,ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS10690,iYO844.BSU28280 HMGL-like,LeuA_dimer k141_770_2 218284.CCDN010000002_gene2122 4.72e-160 455.0 COG0473@1|root,COG0473@2|Bacteria,1TPEM@1239|Firmicutes,4HATP@91061|Bacilli,1ZB3Y@1386|Bacillus 91061|Bacilli CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate leuB GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R00994,R04426,R10052 RC00084,RC00417,RC03036 br01601,ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU28270 Iso_dh k141_19711_1 218284.CCDN010000001_gene1790 4.86e-150 439.0 COG0021@1|root,COG0021@2|Bacteria,1TPIB@1239|Firmicutes,4HADA@91061|Bacilli,1ZBQ6@1386|Bacillus 91061|Bacilli G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate tkt - 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C,Transketolase_N k141_12707_1 218284.CCDN010000005_gene3204 4.6e-127 368.0 COG1063@1|root,COG1063@2|Bacteria,1VRPE@1239|Firmicutes,4HU28@91061|Bacilli,1ZBUV@1386|Bacillus 91061|Bacilli E alcohol dehydrogenase - - 1.1.1.1 ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N k141_25733_1 1379698.RBG1_1C00001G1696 1.36e-52 172.0 COG0590@1|root,COG0590@2|Bacteria,2NPM7@2323|unclassified Bacteria 2|Bacteria FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) tadA GO:0002097,GO:0002100,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 3.5.4.1,3.5.4.33 ko:K01485,ko:K11991 ko00240,ko00330,ko01100,map00240,map00330,map01100 - R00974,R01411,R02922,R10223 RC00074,RC00477,RC00514,RC00809 ko00000,ko00001,ko01000,ko03016 - - - MafB19-deam k141_25733_3 530564.Psta_2921 3.81e-24 98.2 COG2322@1|root,COG2322@2|Bacteria,2J00Y@203682|Planctomycetes 203682|Planctomycetes S Protein of unknown function (DUF420) - - - ko:K08976 - - - - ko00000 - - - DUF420 k141_33942_1 218284.CCDN010000001_gene1450 4.14e-57 188.0 COG0665@1|root,COG0665@2|Bacteria,1VTRW@1239|Firmicutes,4HD2K@91061|Bacilli,1ZCZM@1386|Bacillus 91061|Bacilli E Glycine oxidase thiO GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016043,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0022607,GO:0034641,GO:0036094,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043436,GO:0043799,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0072527,GO:0072528,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.4.3.19 ko:K03153 ko00730,ko01100,map00730,map01100 - R07463 RC01788 ko00000,ko00001,ko01000 - - - DAO k141_7691_1 1294265.JCM21738_71 2.33e-44 150.0 COG1388@1|root,COG1388@2|Bacteria,1V8A5@1239|Firmicutes,4HIV2@91061|Bacilli,1ZG8Q@1386|Bacillus 91061|Bacilli M Lysin motif ypbE - - - - - - - - - - - LysM k141_7691_2 1294265.JCM21738_70 2.81e-58 184.0 COG1266@1|root,COG1266@2|Bacteria,1V4WK@1239|Firmicutes,4HHKM@91061|Bacilli,1ZEBP@1386|Bacillus 91061|Bacilli S metal-dependent membrane protease ypbD - - ko:K07052 - - - - ko00000 - - - Abi k141_10291_1 223926.28808536 1.31e-125 364.0 COG2930@1|root,COG2930@2|Bacteria,1RCH3@1224|Proteobacteria,1S2SV@1236|Gammaproteobacteria,1XT2Q@135623|Vibrionales 135623|Vibrionales S (twin-arginine translocation) pathway signal VPA0371 - - - - - - - - - - - Ysc84 k141_27798_2 1453501.JELR01000001_gene2836 1.33e-39 142.0 COG0568@1|root,COG0568@2|Bacteria,1MUDI@1224|Proteobacteria,1RN8V@1236|Gammaproteobacteria,4641K@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG0568 DNA-directed RNA polymerase, sigma subunit (sigma70 sigma32) rpoS GO:0000988,GO:0000990,GO:0001000,GO:0001121,GO:0001123,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043175,GO:0043254,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - ko:K03087 ko02026,ko05111,map02026,map05111 - - - ko00000,ko00001,ko03021 - - - Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 k141_16232_1 218284.CCDN010000002_gene2251 5.6e-110 330.0 COG0069@1|root,COG0069@2|Bacteria,1TSHA@1239|Firmicutes,4HA97@91061|Bacilli,1ZCQH@1386|Bacillus 91061|Bacilli E Belongs to the glutamate synthase family yerD GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.7.1 ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 - R00021,R10086 RC00006,RC00010 ko00000,ko00001,ko01000 - - - Glu_synthase k141_9287_1 218284.CCDN010000001_gene1350 1.45e-37 129.0 COG4699@1|root,COG4699@2|Bacteria,1VHC7@1239|Firmicutes,4HNQD@91061|Bacilli,1ZJIB@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF1033) - - - - - - - - - - - - DUF1033 k141_18875_1 997296.PB1_05762 5.26e-162 460.0 COG2064@1|root,COG2064@2|Bacteria,1URSD@1239|Firmicutes,4HAR7@91061|Bacilli,1ZF59@1386|Bacillus 91061|Bacilli NU Type II secretion system (T2SS), protein F - - - ko:K12511 - - - - ko00000,ko02044 - - - T2SSF k141_14183_1 1453501.JELR01000001_gene2970 3.79e-164 471.0 COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,1RM8M@1236|Gammaproteobacteria,46473@72275|Alteromonadaceae 1236|Gammaproteobacteria M Transfers the fatty acyl group on membrane lipoproteins lnt GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016021,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031224,GO:0031226,GO:0034645,GO:0036211,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576 - ko:K03820 - - - - ko00000,ko01000 - GT2 iEcSMS35_1347.EcSMS35_0678,iSbBS512_1146.SbBS512_E0590 CN_hydrolase k141_23616_2 1209072.ALBT01000032_gene2003 9.11e-82 253.0 COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,1RM8I@1236|Gammaproteobacteria,1FG05@10|Cellvibrio 1236|Gammaproteobacteria G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) tpiA GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01015 RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 - - - TIM k141_23616_3 1279017.AQYJ01000024_gene840 6.87e-48 158.0 COG1314@1|root,COG1314@2|Bacteria,1N8MF@1224|Proteobacteria,1SD3P@1236|Gammaproteobacteria,467VJ@72275|Alteromonadaceae 1236|Gammaproteobacteria U Preprotein translocase subunit SecG secG GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecG k141_6858_1 644282.Deba_1854 4.52e-27 121.0 COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,42NKH@68525|delta/epsilon subdivisions,2WJ30@28221|Deltaproteobacteria 28221|Deltaproteobacteria L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA recB - 3.1.11.5,3.6.4.12 ko:K03582,ko:K16898 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - PDDEXK_1,UvrD-helicase,UvrD_C k141_15032_1 1294265.JCM21738_4709 1.28e-178 511.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,1ZASV@1386|Bacillus 91061|Bacilli V COG1132 ABC-type multidrug transport system, ATPase and permease components yknU GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702 - ko:K06147,ko:K11085 ko02010,map02010 - - - ko00000,ko00001,ko01000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran k141_27288_1 218284.CCDN010000001_gene514 6.33e-96 296.0 COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,4H9VY@91061|Bacilli,1ZCDT@1386|Bacillus 91061|Bacilli G Belongs to the pyruvate kinase family pyk GO:0001871,GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0030246,GO:0030247,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:2001065 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - PEP-utilizers,PK,PK_C k141_6859_1 1305836.AXVE01000011_gene1018 3.18e-16 79.0 COG3459@1|root,COG3459@2|Bacteria,1TQY8@1239|Firmicutes,4HBZV@91061|Bacilli,26GM9@186818|Planococcaceae 91061|Bacilli G Protein of unknown function (DUF3131) - - - - - - - - - - - - DUF3131,Glycoamylase k141_11657_1 265072.Mfla_2443 3.59e-06 48.9 COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,2VI3M@28216|Betaproteobacteria,2KKUY@206350|Nitrosomonadales 206350|Nitrosomonadales E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine lysA - 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N,Orn_DAP_Arg_deC k141_14184_2 1117379.BABA_19661 3.65e-08 52.0 2DQGP@1|root,336RI@2|Bacteria,1VF4C@1239|Firmicutes,4IDMC@91061|Bacilli,1ZJ9R@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_25928_1 42565.FP66_06395 6.05e-18 79.3 2EGUY@1|root,33AM4@2|Bacteria,1NGGE@1224|Proteobacteria,1SGAZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_18877_1 223926.28805342 7.39e-104 317.0 COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,1RMVN@1236|Gammaproteobacteria,1XSTB@135623|Vibrionales 135623|Vibrionales M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source glmS GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 - R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 - - - GATase_6,SIS k141_22275_1 1116375.VEJY3_21706 5.55e-193 540.0 COG1073@1|root,COG1073@2|Bacteria,1MUCD@1224|Proteobacteria,1RP4I@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Hydrolases of the alpha beta superfamily - - - ko:K06889 - - - - ko00000 - - - AXE1,Abhydrolase_1,BAAT_C,DLH,DUF1100,Hydrolase_4,Peptidase_S15,RMMBL k141_9290_1 1211814.CAPG01000003_gene79 4.8e-77 247.0 COG3391@1|root,COG4632@1|root,COG3391@2|Bacteria,COG4632@2|Bacteria,1VA7N@1239|Firmicutes,4HEEV@91061|Bacilli,1ZHY4@1386|Bacillus 91061|Bacilli G Exopolysaccharide biosynthesis protein - - - - - - - - - - - - SLH k141_4343_1 218284.CCDN010000001_gene1424 2.84e-45 149.0 COG3427@1|root,COG3427@2|Bacteria,1V817@1239|Firmicutes,4HJA1@91061|Bacilli,1ZH31@1386|Bacillus 91061|Bacilli S Carbon monoxide dehydrogenase subunit G (CoxG) - - - - - - - - - - - - COXG,Polyketide_cyc2 k141_4343_2 218284.CCDN010000001_gene1423 8.72e-18 80.5 COG1011@1|root,COG1011@2|Bacteria,1TS3W@1239|Firmicutes,4HADE@91061|Bacilli,1ZBN8@1386|Bacillus 91061|Bacilli S HAD-hyrolase-like ysaA - 3.1.3.5,3.8.1.2 ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346,R05287 RC00017,RC00697 ko00000,ko00001,ko01000 - - - HAD_2 k141_23617_1 1279017.AQYJ01000028_gene2320 3.04e-135 410.0 COG0709@1|root,COG1252@1|root,COG0709@2|Bacteria,COG1252@2|Bacteria,1MWFG@1224|Proteobacteria,1RQ5Q@1236|Gammaproteobacteria,465WT@72275|Alteromonadaceae 1236|Gammaproteobacteria CE Belongs to the selenophosphate synthase 1 family. Class I subfamily - - 2.7.9.3 ko:K01008 ko00450,ko01100,map00450,map01100 - R03595 RC00002,RC02878 ko00000,ko00001,ko01000,ko03016 - - - AIRS,AIRS_C,Pyr_redox_2 k141_27289_2 180281.CPCC7001_1180 4.7e-51 175.0 COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1G0NF@1117|Cyanobacteria,22S03@167375|Cyanobium 1117|Cyanobacteria H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate ribD GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0016070,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 1.1.1.193,3.5.4.26 ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 M00125 R03458,R03459 RC00204,RC00933 ko00000,ko00001,ko00002,ko01000 - - - RibD_C,dCMP_cyt_deam_1 k141_926_1 1294265.JCM21738_2068 5.8e-43 151.0 COG0403@1|root,COG0403@2|Bacteria,1TQGG@1239|Firmicutes,4HA7P@91061|Bacilli,1ZB0H@1386|Bacillus 91061|Bacilli E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor gcvPA - 1.4.4.2 ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 - R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko01000 - - - GDC-P k141_926_2 1294265.JCM21738_2069 1.19e-50 169.0 COG0404@1|root,COG0404@2|Bacteria,1TRKX@1239|Firmicutes,4H9MX@91061|Bacilli,1ZAS5@1386|Bacillus 91061|Bacilli E The glycine cleavage system catalyzes the degradation of glycine gcvT - 2.1.2.10 ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 M00532 R01221,R02300,R04125 RC00022,RC00069,RC00183,RC02834 ko00000,ko00001,ko00002,ko01000 - - - GCV_T,GCV_T_C k141_3131_1 218284.CCDN010000001_gene31 1.52e-186 535.0 COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,4HAWN@91061|Bacilli,1ZC17@1386|Bacillus 91061|Bacilli L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) recG GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecG_wedge k141_6860_2 1042377.AFPJ01000055_gene985 1.5e-74 223.0 COG0099@1|root,COG0099@2|Bacteria,1RD1G@1224|Proteobacteria,1S3NX@1236|Gammaproteobacteria,467N1@72275|Alteromonadaceae 1236|Gammaproteobacteria J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits rpsM GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02952 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S13 k141_19895_1 1279017.AQYJ01000026_gene25 5.29e-154 442.0 COG2813@1|root,COG2813@2|Bacteria,1MXE9@1224|Proteobacteria,1RQCH@1236|Gammaproteobacteria,466JK@72275|Alteromonadaceae 1236|Gammaproteobacteria J Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle rsmC GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052914,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.172 ko:K00564 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - MTS,MTS_N k141_25929_1 485913.Krac_0465 1.33e-20 89.4 COG1853@1|root,COG1853@2|Bacteria 2|Bacteria S FMN binding - - - - - - - - - - - - Flavin_Reduct k141_14186_1 1294265.JCM21738_1615 1.33e-107 332.0 COG1404@1|root,COG1404@2|Bacteria,1TQRU@1239|Firmicutes,4HAZA@91061|Bacilli,1ZAZK@1386|Bacillus 91061|Bacilli O Belongs to the peptidase S8 family - - - - - - - - - - - - Inhibitor_I9,PA,PPC,Peptidase_S8,SLH k141_34128_1 391626.OAN307_c03800 9.17e-186 528.0 COG2826@1|root,COG2826@2|Bacteria,1PP49@1224|Proteobacteria,2TRVA@28211|Alphaproteobacteria 28211|Alphaproteobacteria L COG2826 Transposase and inactivated derivatives, IS30 family - - - - - - - - - - - - HTH_38,rve k141_22276_1 218284.CCDN010000004_gene3109 1.18e-175 493.0 COG4989@1|root,COG4989@2|Bacteria,1TQ12@1239|Firmicutes,4HA57@91061|Bacilli,1ZD8D@1386|Bacillus 91061|Bacilli S Oxidoreductase ycsN - - - - - - - - - - - Aldo_ket_red k141_15034_1 997296.PB1_16584 8.41e-41 148.0 COG0392@1|root,COG0392@2|Bacteria,1V1W5@1239|Firmicutes,4HGDX@91061|Bacilli,1ZGE8@1386|Bacillus 91061|Bacilli S Lysylphosphatidylglycerol synthase TM region mprF - - ko:K07027 - - - - ko00000,ko02000 4.D.2 - - LPG_synthase_TM k141_15034_2 265729.GS18_0213230 7.03e-23 95.9 COG0451@1|root,COG0451@2|Bacteria,1VP6I@1239|Firmicutes,4ISWU@91061|Bacilli 91061|Bacilli M Nad-dependent epimerase dehydratase yfnG - 4.2.1.45,4.2.1.46 ko:K01709,ko:K01710 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 M00793 R02426,R06513 RC00402 ko00000,ko00001,ko00002,ko01000 - - - Epimerase,GDP_Man_Dehyd k141_27943_1 1111732.AZOD01000055_gene246 1.29e-22 88.6 2EG3W@1|root,339VW@2|Bacteria,1NHIR@1224|Proteobacteria,1SGXB@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_7925_1 1116375.VEJY3_07420 1.47e-25 104.0 2AX11@1|root,31NZ2@2|Bacteria,1QKNB@1224|Proteobacteria,1TIST@1236|Gammaproteobacteria,1XZKD@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_7925_2 1116375.VEJY3_07425 1.06e-81 251.0 2967A@1|root,2ZTHD@2|Bacteria,1P6FA@1224|Proteobacteria,1SV2R@1236|Gammaproteobacteria,1XYRT@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_7925_3 1116375.VEJY3_07430 2.83e-73 223.0 2B4NJ@1|root,31XEU@2|Bacteria,1QK49@1224|Proteobacteria,1TI76@1236|Gammaproteobacteria,1XYJ4@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_7925_4 223926.28806562 3.3e-65 200.0 2B5P7@1|root,31YIN@2|Bacteria,1QK4P@1224|Proteobacteria,1TI7Q@1236|Gammaproteobacteria,1XYKG@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_6861_1 218284.CCDN010000006_gene3605 3.03e-82 254.0 COG4447@1|root,COG4447@2|Bacteria,1TRJ4@1239|Firmicutes,4HBUI@91061|Bacilli,1ZCUG@1386|Bacillus 91061|Bacilli S cellulose binding - - - - - - - - - - - - Sortilin-Vps10 k141_19896_1 1123073.KB899241_gene3167 1.43e-21 98.6 28MY3@1|root,2ZB50@2|Bacteria,1R833@1224|Proteobacteria,1RY08@1236|Gammaproteobacteria,1XB4R@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - k141_23619_1 278957.ABEA03000155_gene391 2.68e-52 179.0 COG0463@1|root,COG0463@2|Bacteria,46SXD@74201|Verrucomicrobia,3K8TU@414999|Opitutae 414999|Opitutae M Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 k141_14187_1 1121921.KB898714_gene1821 1.65e-17 82.0 COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,1RP23@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol ispE GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006629,GO:0006720,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050515,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576 2.7.1.148 ko:K00919 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05634 RC00002,RC01439 ko00000,ko00001,ko00002,ko01000 - - iEC55989_1330.EC55989_1304 GHMP_kinases_C,GHMP_kinases_N k141_11659_1 1294265.JCM21738_3528 4.38e-32 118.0 COG2273@1|root,COG2273@2|Bacteria,1TR5U@1239|Firmicutes,4HACU@91061|Bacilli,1ZR43@1386|Bacillus 91061|Bacilli G Glycosyl hydrolases family 16 bglA3 - 3.2.1.18 ko:K01186 ko00511,ko00600,ko04142,map00511,map00600,map04142 - R04018 RC00028,RC00077 ko00000,ko00001,ko01000,ko02042 - GH33 - CBM_4_9,Glyco_hydro_16,RicinB_lectin_2 k141_11659_2 1423321.AS29_11200 2.17e-197 556.0 COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4H9KU@91061|Bacilli,1ZBF2@1386|Bacillus 91061|Bacilli G Belongs to the glycosyl hydrolase 1 family bglA7 - 3.2.1.21 ko:K05350 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 - R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - - - Glyco_hydro_1 k141_18880_1 518766.Rmar_1593 6.47e-61 202.0 COG2987@1|root,COG2987@2|Bacteria,4NF2P@976|Bacteroidetes 976|Bacteroidetes E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate hutU - 4.2.1.49 ko:K01712 ko00340,ko01100,map00340,map01100 M00045 R02914 RC00804 ko00000,ko00001,ko00002,ko01000 - - - Urocanase,Urocanase_C,Urocanase_N k141_24641_1 550540.Fbal_2211 3.31e-266 744.0 COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,1RMT7@1236|Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - DUF885 k141_929_1 218284.CCDN010000006_gene3636 8.65e-101 306.0 COG0457@1|root,COG0457@2|Bacteria,1UBH2@1239|Firmicutes,4HB47@91061|Bacilli,1ZD40@1386|Bacillus 91061|Bacilli S COG0457 FOG TPR repeat yvcD - - - - - - - - - - - HTH_psq,TPR_16,TPR_19,TPR_2,TPR_8 k141_10416_3 1279017.AQYJ01000023_gene3233 4.13e-28 103.0 2EQAZ@1|root,33HX4@2|Bacteria,1NGHQ@1224|Proteobacteria,1SH13@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - IV02_08010 - - - - - - - - - - - - k141_19897_1 218284.CCDN010000001_gene1272 1.53e-119 349.0 COG0253@1|root,COG0253@2|Bacteria,1TPMN@1239|Firmicutes,4HBH4@91061|Bacilli,1ZD98@1386|Bacillus 91061|Bacilli E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan dapF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 - - - DAP_epimerase k141_9294_1 867903.ThesuDRAFT_00175 1.44e-22 102.0 COG0323@1|root,COG0323@2|Bacteria,1TPGK@1239|Firmicutes,24902@186801|Clostridia,3WCFA@538999|Clostridiales incertae sedis 186801|Clostridia L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex mutL - - ko:K03572 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - DNA_mis_repair,HATPase_c_3,MutL_C k141_18881_1 218284.CCDN010000001_gene1807 5.52e-86 273.0 COG0323@1|root,COG0323@2|Bacteria,1TPGK@1239|Firmicutes,4HB34@91061|Bacilli,1ZB9X@1386|Bacillus 91061|Bacilli L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex mutL GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032300,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1990391 - ko:K03572 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - DNA_mis_repair,HATPase_c_3,MutL_C k141_14189_1 1294265.JCM21738_4134 2.66e-74 224.0 COG1607@1|root,COG1607@2|Bacteria,1V4RQ@1239|Firmicutes,4HH3S@91061|Bacilli,1ZQP7@1386|Bacillus 91061|Bacilli I Thioesterase superfamily - - - - - - - - - - - - 4HBT k141_11660_1 406124.ACPC01000050_gene362 1.25e-15 73.2 COG0823@1|root,COG0823@2|Bacteria,1VFY2@1239|Firmicutes,4HP5R@91061|Bacilli,1ZIV5@1386|Bacillus 91061|Bacilli U Protein of unknown function (DUF3889) - - - - - - - - - - - - DUF3889 k141_11660_2 218284.CCDN010000001_gene592 2.16e-27 106.0 COG2102@1|root,COG2102@2|Bacteria,1V5NH@1239|Firmicutes,4HID4@91061|Bacilli,1ZDP8@1386|Bacillus 91061|Bacilli S Diphthamide synthase - - - - - - - - - - - - Diphthami_syn_2 k141_37521_1 1116375.VEJY3_16021 8.64e-172 480.0 COG0235@1|root,COG0235@2|Bacteria,1MWP9@1224|Proteobacteria,1RQNI@1236|Gammaproteobacteria,1XUCH@135623|Vibrionales 135623|Vibrionales G Class II Aldolase and Adducin N-terminal domain - - - - - - - - - - - - Aldolase_II k141_37521_2 1116375.VEJY3_22996 2.21e-84 250.0 COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,1S607@1236|Gammaproteobacteria,1XYRW@135623|Vibrionales 135623|Vibrionales O Hsp20/alpha crystallin family - - - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 k141_37521_3 1116375.VEJY3_23001 9.81e-155 438.0 COG2267@1|root,COG2267@2|Bacteria,1N4BU@1224|Proteobacteria,1S9K5@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_6,Hydrolase_4 k141_930_1 161528.ED21_24651 1.04e-09 58.9 COG3324@1|root,COG3324@2|Bacteria,1R81W@1224|Proteobacteria,2U6BE@28211|Alphaproteobacteria,2K4NC@204457|Sphingomonadales 204457|Sphingomonadales S enzyme related to lactoylglutathione lyase - - - ko:K06996 - - - - ko00000 - - - Glyoxalase k141_930_2 1118235.CAJH01000048_gene3010 2.56e-57 180.0 COG5507@1|root,COG5507@2|Bacteria,1RHC1@1224|Proteobacteria,1S6KT@1236|Gammaproteobacteria,1X6VN@135614|Xanthomonadales 135614|Xanthomonadales S RNA signal recognition particle - - - - - - - - - - - - DUF1428 k141_22277_1 218284.CCDN010000002_gene2293 4.15e-148 427.0 COG0477@1|root,COG2814@2|Bacteria,1TPVC@1239|Firmicutes,4HB6R@91061|Bacilli,1ZS47@1386|Bacillus 91061|Bacilli EGP Major Facilitator Superfamily - - - ko:K08152 - - - - ko00000,ko02000 2.A.1.2 - - MFS_1,Sugar_tr k141_22277_2 218284.CCDN010000002_gene2292 3.8e-122 350.0 COG1309@1|root,COG1309@2|Bacteria,1VCV2@1239|Firmicutes,4HN1G@91061|Bacilli,1ZHKV@1386|Bacillus 91061|Bacilli K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N k141_12874_1 1116375.VEJY3_13750 3.51e-207 600.0 COG0553@1|root,COG0553@2|Bacteria,1MX6H@1224|Proteobacteria,1RNRZ@1236|Gammaproteobacteria,1XTMU@135623|Vibrionales 135623|Vibrionales K Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair rapA GO:0000166,GO:0003674,GO:0003824,GO:0004386,GO:0005488,GO:0005524,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - ko:K03580 - - - - ko00000,ko01000,ko03021 - - - Helicase_C,RapA_C,SNF2_N k141_12874_2 674977.VMC_34830 6.96e-269 740.0 COG1914@1|root,COG1914@2|Bacteria,1MWET@1224|Proteobacteria,1RY2N@1236|Gammaproteobacteria,1XW0V@135623|Vibrionales 135623|Vibrionales P Mn2 and Fe2 transporters of the NRAMP family - - - - - - - - - - - - Nramp k141_12874_3 1116375.VEJY3_13740 9.83e-183 508.0 COG0564@1|root,COG0564@2|Bacteria,1MVJ5@1224|Proteobacteria,1RN4N@1236|Gammaproteobacteria,1XURW@135623|Vibrionales 135623|Vibrionales J Responsible for synthesis of pseudouridine from uracil rluA GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.28,5.4.99.29 ko:K06177 - - - - ko00000,ko01000,ko03009,ko03016 - - - PseudoU_synth_2 k141_12874_4 1116375.VEJY3_13735 2.73e-199 555.0 COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,1RPM1@1236|Gammaproteobacteria,1XTHS@135623|Vibrionales 135623|Vibrionales C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family hprA - 1.1.1.29 ko:K00018 ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200 M00346 R00717,R01388 RC00031,RC00042 ko00000,ko00001,ko00002,ko01000 - - - 2-Hacid_dh,2-Hacid_dh_C k141_12874_5 1219076.N646_1769 1.22e-105 306.0 COG3028@1|root,COG3028@2|Bacteria,1MZ4R@1224|Proteobacteria,1S9JJ@1236|Gammaproteobacteria,1XTXV@135623|Vibrionales 135623|Vibrionales S Belongs to the UPF0307 family yjgA - - ko:K09889 - - - - ko00000,ko03009 - - - DUF615 k141_4364_1 1078085.HMPREF1210_00063 8.31e-28 110.0 COG1597@1|root,COG1597@2|Bacteria,1TUH3@1239|Firmicutes,4IR1U@91061|Bacilli,26D20@186818|Planococcaceae 91061|Bacilli I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase ytlR - - - - - - - - - - - DAGK_acc,DAGK_cat k141_4364_2 218284.CCDN010000008_gene4198 2.34e-19 87.0 COG1523@1|root,COG1523@2|Bacteria,1TP3M@1239|Firmicutes,4HBP5@91061|Bacilli,1ZC85@1386|Bacillus 91061|Bacilli G Belongs to the glycosyl hydrolase 13 family amyX - 3.2.1.41 ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 - R02111 - ko00000,ko00001,ko01000 - CBM48,GH13 - Alpha-amylase,CBM_48 k141_19914_1 552811.Dehly_1517 1.26e-22 102.0 COG1948@1|root,COG4880@2|Bacteria 2|Bacteria L resolution of meiotic recombination intermediates - - - - - - - - - - - - Beta_propel,Cu_amine_oxidN1 k141_957_1 1307436.PBF_13284 2.31e-77 236.0 COG1971@1|root,COG1971@2|Bacteria,1V4BC@1239|Firmicutes,4HH29@91061|Bacilli,1ZCPR@1386|Bacillus 91061|Bacilli P Probably functions as a manganese efflux pump ytaF - - - - - - - - - - - Mntp k141_34143_1 1219076.N646_3545 5.85e-18 82.4 COG1164@1|root,COG1164@2|Bacteria,1MUYZ@1224|Proteobacteria,1RYXN@1236|Gammaproteobacteria,1XTZF@135623|Vibrionales 135623|Vibrionales E Peptidase family M3 - - - - - - - - - - - - Peptidase_M3 k141_34143_2 1116375.VEJY3_16131 6.68e-17 76.3 2AWR4@1|root,31NN2@2|Bacteria,1QKCN@1224|Proteobacteria,1TIG5@1236|Gammaproteobacteria,1XZ2P@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_27959_2 218284.CCDN010000002_gene2092 1.56e-77 238.0 COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,4HA59@91061|Bacilli,1ZB8X@1386|Bacillus 91061|Bacilli I 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain hbd - 1.1.1.157 ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 - R01976,R05576,R06941 RC00029,RC00117 ko00000,ko00001,ko01000 - - - 3HCDH,3HCDH_N k141_27327_2 218284.CCDN010000005_gene3269 4.19e-37 132.0 COG2267@1|root,COG2267@2|Bacteria,1UZM1@1239|Firmicutes,4HFJW@91061|Bacilli,1ZD5F@1386|Bacillus 91061|Bacilli I carboxylic ester hydrolase activity yjaU - - - - - - - - - - - Hydrolase_4 k141_18915_1 344747.PM8797T_05705 2.27e-140 409.0 COG0604@1|root,COG0604@2|Bacteria,2J2QJ@203682|Planctomycetes 203682|Planctomycetes C Zinc-binding dehydrogenase - - - - - - - - - - - - ADH_N,ADH_zinc_N_2 k141_11681_1 218284.CCDN010000002_gene2703 4.32e-160 451.0 COG3739@1|root,COG3739@2|Bacteria,1TSSG@1239|Firmicutes,4H9MC@91061|Bacilli,1ZCEJ@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF817) yoaT - - - - - - - - - - - DUF817 k141_25944_1 218284.CCDN010000009_gene4315 5.69e-141 418.0 COG0601@1|root,COG1173@1|root,COG0601@2|Bacteria,COG1173@2|Bacteria,1V21B@1239|Firmicutes,4HDPU@91061|Bacilli,1ZEQ7@1386|Bacillus 91061|Bacilli EP Binding-protein-dependent transport system inner membrane component - - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1,Peptidase_M1 k141_14222_1 1279017.AQYJ01000022_gene2641 1.93e-35 122.0 2EHQ3@1|root,33BFV@2|Bacteria,1NHBP@1224|Proteobacteria,1SDE8@1236|Gammaproteobacteria,46CFB@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_22300_2 1042377.AFPJ01000012_gene1371 8.55e-215 593.0 COG1834@1|root,COG1834@2|Bacteria,1R5UT@1224|Proteobacteria,1RYEQ@1236|Gammaproteobacteria,46AEJ@72275|Alteromonadaceae 1236|Gammaproteobacteria E Amidinotransferase - - - - - - - - - - - - Amidinotransf k141_22300_3 1042377.AFPJ01000012_gene1369 3.32e-68 209.0 2C46F@1|root,32SRD@2|Bacteria,1N540@1224|Proteobacteria,1S8P6@1236|Gammaproteobacteria,46CCG@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_1887_2 1279017.AQYJ01000020_gene1264 7.7e-216 599.0 COG0533@1|root,COG0533@2|Bacteria,1MU6S@1224|Proteobacteria,1RN8M@1236|Gammaproteobacteria,465FN@72275|Alteromonadaceae 1236|Gammaproteobacteria O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction tsaD GO:0000287,GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140030,GO:0140032,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 ko:K01409 - - R10648 RC00070,RC00416 ko00000,ko01000,ko03016 - - - Peptidase_M22 k141_23643_3 1408303.JNJJ01000045_gene1132 2.22e-143 407.0 COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,4HAK4@91061|Bacilli,1ZB14@1386|Bacillus 91061|Bacilli J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release rplA GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02863 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L1 k141_23643_4 1294265.JCM21738_4160 1.13e-47 156.0 COG0244@1|root,COG0244@2|Bacteria,1V3JJ@1239|Firmicutes,4HH0N@91061|Bacilli,1ZBGK@1386|Bacillus 91061|Bacilli J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors rplJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02864 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L10 k141_27328_1 218284.CCDN010000002_gene2394 1.83e-110 328.0 COG0814@1|root,COG0814@2|Bacteria,1UIWV@1239|Firmicutes,4ISV2@91061|Bacilli 91061|Bacilli E Spore germination protein - - - - - - - - - - - - Spore_permease k141_17387_2 1123279.ATUS01000001_gene2577 6.13e-96 290.0 COG0300@1|root,COG0300@2|Bacteria,1R9VQ@1224|Proteobacteria,1S1WG@1236|Gammaproteobacteria,1J9II@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S KR domain - - - - - - - - - - - - adh_short k141_6882_1 1279017.AQYJ01000020_gene1229 5.5e-215 604.0 COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,1RMWS@1236|Gammaproteobacteria,4646Q@72275|Alteromonadaceae 1236|Gammaproteobacteria F COG0138 AICAR transformylase IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) purH GO:0003674,GO:0003824,GO:0004643,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 - - iEcHS_1320.EcHS_A4240,iPC815.YPO3728 AICARFT_IMPCHas,MGS k141_6882_2 1279017.AQYJ01000020_gene1228 1.24e-59 184.0 COG2901@1|root,COG2901@2|Bacteria,1N7MJ@1224|Proteobacteria,1SD35@1236|Gammaproteobacteria,468HA@72275|Alteromonadaceae 1236|Gammaproteobacteria K Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters fis GO:0000018,GO:0000229,GO:0000785,GO:0000786,GO:0000787,GO:0000789,GO:0000976,GO:0000984,GO:0000985,GO:0001017,GO:0001046,GO:0001047,GO:0001067,GO:0001121,GO:0001130,GO:0001131,GO:0001140,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008301,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016032,GO:0016070,GO:0018130,GO:0019042,GO:0019045,GO:0019046,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031421,GO:0032359,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0042803,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044374,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044427,GO:0044444,GO:0044446,GO:0044464,GO:0044815,GO:0045892,GO:0045893,GO:0045911,GO:0045934,GO:0045935,GO:0046483,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051054,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - ko:K03557 ko05111,map05111 - - - ko00000,ko00001,ko03000,ko03036,ko03400 - - - HTH_8 k141_37792_2 218284.CCDN010000007_gene3954 3.34e-54 186.0 COG0247@1|root,COG2181@1|root,COG0247@2|Bacteria,COG2181@2|Bacteria,1TPG1@1239|Firmicutes,4HB2J@91061|Bacilli,1ZBAJ@1386|Bacillus 91061|Bacilli C COG0247 Fe-S oxidoreductase ywjF - - - - - - - - - - - CCG,Fer4_8 k141_33110_1 218284.CCDN010000001_gene1676 9.95e-91 272.0 COG4336@1|root,COG4336@2|Bacteria,1TRY8@1239|Firmicutes,4HCWD@91061|Bacilli,1ZB87@1386|Bacillus 91061|Bacilli S Belongs to the D-glutamate cyclase family ycsI - - - - - - - - - - - DUF1445 k141_8017_1 366602.Caul_3957 1.54e-68 221.0 COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2TQND@28211|Alphaproteobacteria,2KG72@204458|Caulobacterales 204458|Caulobacterales E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - 2.6.1.18 ko:K00822 ko00280,ko00410,ko00640,ko01100,map00280,map00410,map00640,map01100 - R00907,R04187 RC00008,RC00062,RC00160 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_3 k141_8017_2 999541.bgla_1g28400 3.02e-16 74.7 COG0662@1|root,COG1476@1|root,COG0662@2|Bacteria,COG1476@2|Bacteria,1QTWE@1224|Proteobacteria,2VQIT@28216|Betaproteobacteria,1K47B@119060|Burkholderiaceae 28216|Betaproteobacteria K Cupin 2, conserved barrel domain protein - - - - - - - - - - - - Cupin_2,HTH_3,HTH_31 k141_2161_1 1340434.AXVA01000008_gene3474 3.4e-56 177.0 2BT4C@1|root,32N8Y@2|Bacteria,1V8XA@1239|Firmicutes,4HKBC@91061|Bacilli,1ZG1Z@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_16514_1 218284.CCDN010000005_gene3479 7.48e-148 422.0 COG1226@1|root,COG1226@2|Bacteria,1TS7X@1239|Firmicutes,4HCIB@91061|Bacilli,1ZCD3@1386|Bacillus 91061|Bacilli P COG1226 Kef-type K transport systems yugO - - ko:K10716 - - - - ko00000,ko02000 1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6 - - Ion_trans_2,TrkA_N k141_8018_1 1033734.CAET01000042_gene517 2.74e-14 72.0 COG0673@1|root,COG0673@2|Bacteria,1TQ72@1239|Firmicutes,4HCS4@91061|Bacilli,1ZCPA@1386|Bacillus 91061|Bacilli S Oxidoreductase family, C-terminal alpha/beta domain - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C k141_21183_2 1294265.JCM21738_1069 3.63e-40 132.0 29SGJ@1|root,30DMJ@2|Bacteria,1UBFB@1239|Firmicutes,4IMU0@91061|Bacilli,1ZKUH@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_3387_1 926550.CLDAP_30940 1.98e-87 272.0 COG0076@1|root,COG0076@2|Bacteria,2G7N6@200795|Chloroflexi 200795|Chloroflexi E Pyridoxal-dependent decarboxylase conserved domain - - 4.1.1.105,4.1.1.28,4.1.2.27 ko:K01593,ko:K01634 ko00350,ko00360,ko00380,ko00600,ko00901,ko00950,ko00965,ko01100,ko01110,ko04071,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00600,map00901,map00950,map00965,map01100,map01110,map04071,map04726,map04728,map05030,map05031,map05034 M00037,M00042,M00100 R00685,R00699,R00736,R02080,R02464,R02701,R04909,R06516 RC00264,RC00299,RC00721,RC01266 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyridoxal_deC k141_36490_1 1116375.VEJY3_10775 1.25e-173 497.0 COG3067@1|root,COG3067@2|Bacteria,1MV0F@1224|Proteobacteria,1RPE3@1236|Gammaproteobacteria,1XT42@135623|Vibrionales 135623|Vibrionales P ) H( ) antiporter that extrudes sodium in exchange for external protons nhaB GO:0003674,GO:0005215,GO:0005451,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015491,GO:0015672,GO:0016020,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0035725,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0099516,GO:1902600 - ko:K03314 - - - - ko00000,ko02000 2.A.34.1 - - NhaB k141_36490_2 1116375.VEJY3_10770 2.57e-188 524.0 COG2186@1|root,COG2186@2|Bacteria,1MW7M@1224|Proteobacteria,1RMRE@1236|Gammaproteobacteria,1XTXB@135623|Vibrionales 135623|Vibrionales K Multifunctional regulator of fatty acid metabolism fadR GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010563,GO:0010565,GO:0010605,GO:0010629,GO:0019216,GO:0019217,GO:0019219,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045833,GO:0045892,GO:0045934,GO:0045936,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0051171,GO:0051172,GO:0051174,GO:0051252,GO:0051253,GO:0060255,GO:0062012,GO:0065007,GO:0071071,GO:0071072,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1903725,GO:1903726,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - ko:K03603 - - - - ko00000,ko03000 - - - FadR_C,GntR k141_36490_3 1116375.VEJY3_10765 1.16e-158 448.0 2AZSG@1|root,31S1S@2|Bacteria,1QJ9C@1224|Proteobacteria,1TH7Y@1236|Gammaproteobacteria,1XSAD@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_36490_5 1116375.VEJY3_10760 0.0 1360.0 COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,1RMYM@1236|Gammaproteobacteria,1XUTN@135623|Vibrionales 135623|Vibrionales J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation metG GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1g,tRNA_bind k141_37794_1 153948.NAL212_0013 7.75e-113 329.0 COG3676@1|root,COG3676@2|Bacteria,1QTF7@1224|Proteobacteria,2VSUV@28216|Betaproteobacteria 28216|Betaproteobacteria L ISXO2-like transposase domain - - - ko:K07488 - - - - ko00000 - - - DDE_Tnp_IS1595 k141_8019_1 1453501.JELR01000002_gene696 1.37e-37 136.0 COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,1RND5@1236|Gammaproteobacteria,464ZN@72275|Alteromonadaceae 1236|Gammaproteobacteria CH COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases visC GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016491,GO:0019168,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901576,GO:1901661,GO:1901663 - ko:K03184,ko:K18800 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04987,R06146,R08768,R08775 RC00046,RC01254 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_3 k141_8019_2 1453501.JELR01000002_gene697 2.27e-23 97.8 COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,1RMS3@1236|Gammaproteobacteria,464X1@72275|Alteromonadaceae 1236|Gammaproteobacteria CH COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases ubiH GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008681,GO:0009058,GO:0009108,GO:0009314,GO:0009416,GO:0009628,GO:0009987,GO:0016491,GO:0016705,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0050896,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901576,GO:1901661,GO:1901663 - ko:K03185,ko:K18800 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04987,R04989,R08768,R08773 RC00046,RC02670 ko00000,ko00001,ko00002,ko01000 - - iB21_1397.B21_02702,iECBD_1354.ECBD_0830,iECB_1328.ECB_02739,iECD_1391.ECD_02739,iEcHS_1320.EcHS_A3066 FAD_binding_3 k141_17678_1 218284.CCDN010000001_gene1552 1.92e-77 253.0 COG0768@1|root,COG0768@2|Bacteria,1TQHY@1239|Firmicutes,4HAFX@91061|Bacilli,1ZBJM@1386|Bacillus 91061|Bacilli M penicillin-binding protein pbpH - - ko:K21465 ko00550,map00550 - - - ko00000,ko00001,ko01011 - - - PBP_dimer,Transpeptidase k141_17678_2 406124.ACPC01000046_gene2435 1.68e-20 87.8 COG4326@1|root,COG4326@2|Bacteria,1VHE9@1239|Firmicutes,4HP75@91061|Bacilli,1ZJ9B@1386|Bacillus 91061|Bacilli S SpoOM protein - - - ko:K06377 - - - - ko00000 - - - Spo0M k141_29701_1 218284.CCDN010000008_gene4214 8.14e-52 194.0 COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,4HA1S@91061|Bacilli,1ZAYY@1386|Bacillus 91061|Bacilli D Belongs to the FtsK SpoIIIE SftA family sftA - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_SpoIIIE,Ftsk_gamma k141_10648_1 218284.CCDN010000001_gene626 5.42e-77 238.0 COG1792@1|root,COG1792@2|Bacteria,1TR1V@1239|Firmicutes,4HB0K@91061|Bacilli,1ZC8X@1386|Bacillus 91061|Bacilli M Involved in formation and maintenance of cell shape mreC GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0022603,GO:0022604,GO:0030428,GO:0042546,GO:0043621,GO:0044085,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944 - ko:K03570 - - - - ko00000,ko03036 9.B.157.1 - - MreC k141_4617_1 935836.JAEL01000010_gene3775 5.96e-153 434.0 COG0042@1|root,COG0042@2|Bacteria,1TQ2R@1239|Firmicutes,4HA9K@91061|Bacilli,1ZBSF@1386|Bacillus 91061|Bacilli J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines yfjN - - - - - - - - - - - Dus k141_34413_1 218284.CCDN010000006_gene3591 1.45e-87 258.0 COG2764@1|root,COG2764@2|Bacteria,1V3WE@1239|Firmicutes,4HHHS@91061|Bacilli,1ZGHJ@1386|Bacillus 91061|Bacilli S protein conserved in bacteria phnB7 - - ko:K04750 - - - - ko00000 - - - 3-dmu-9_3-mt k141_8063_1 218284.CCDN010000001_gene1804 1.53e-111 342.0 COG2366@1|root,COG2366@2|Bacteria,1UFHA@1239|Firmicutes,4HACM@91061|Bacilli,1ZCMT@1386|Bacillus 91061|Bacilli S Penicillin amidase acyII - 3.5.1.11 ko:K01434 ko00311,ko01130,map00311,map01130 - R02170 RC00166,RC00328 ko00000,ko00001,ko01000,ko01002 - - - Penicil_amidase k141_30538_1 1132442.KB889755_gene4031 5.84e-27 114.0 COG3291@1|root,COG5184@1|root,COG3291@2|Bacteria,COG5184@2|Bacteria,1VD3B@1239|Firmicutes,4IQ9J@91061|Bacilli,1ZGUI@1386|Bacillus 91061|Bacilli DZ Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - - - - - - - - - - - k141_10649_2 1131730.BAVI_13429 5.72e-34 123.0 293T3@1|root,2ZR8H@2|Bacteria,1V593@1239|Firmicutes,4HG8Q@91061|Bacilli,1ZFS5@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2975) - - - - - - - - - - - - DUF2975 k141_28252_1 218284.CCDN010000012_gene4443 1.66e-94 277.0 COG1335@1|root,COG1335@2|Bacteria,1V2DX@1239|Firmicutes,4HJMV@91061|Bacilli,1ZGBB@1386|Bacillus 91061|Bacilli Q Isochorismatase family yaaI - - - - - - - - - - - Isochorismatase k141_15253_1 218284.CCDN010000001_gene203 7.67e-93 277.0 COG0390@1|root,COG0390@2|Bacteria,1UY1N@1239|Firmicutes,4HDM4@91061|Bacilli,1ZB6C@1386|Bacillus 91061|Bacilli S transport system, permease component yjkA GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0009987,GO:0015075,GO:0016020,GO:0016021,GO:0019725,GO:0022857,GO:0030003,GO:0031224,GO:0031226,GO:0034220,GO:0042592,GO:0044425,GO:0044459,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071944,GO:0098771 - ko:K02069 - M00211 - - ko00000,ko00002,ko02000 9.B.25.1 - - UPF0014 k141_29702_2 1416752.AYME01000023_gene3102 8.8e-17 89.0 COG4383@1|root,COG4383@2|Bacteria,2H8VW@201174|Actinobacteria,4FMZZ@85023|Microbacteriaceae 201174|Actinobacteria S Protein of unknown function (DUF935) - - - - - - - - - - - - DUF935 k141_3423_1 377629.TERTU_2852 3.06e-33 129.0 COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,1RN14@1236|Gammaproteobacteria,2PNEG@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria D TilS substrate C-terminal domain tilS GO:0002097,GO:0002101,GO:0002136,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016879,GO:0032267,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 6.3.4.19 ko:K04075 - - R09597 RC02633,RC02634 ko00000,ko01000,ko03016 - - - ATP_bind_3,TilS,TilS_C k141_21208_1 876269.ARWA01000001_gene3098 2.47e-05 47.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TQS3@28211|Alphaproteobacteria,3NAEK@45404|Beijerinckiaceae 28211|Alphaproteobacteria T 7TMR-DISM extracellular 2 MA20_18100 - 3.1.4.52 ko:K13245 ko04112,map04112 - R08991 RC00296 ko00000,ko00001,ko01000 - - - 7TMR-DISMED2,7TMR-DISM_7TM,EAL,GGDEF,PAS_3 k141_21208_2 42565.FP66_08305 6.44e-39 130.0 2EI8B@1|root,33BZN@2|Bacteria,1NGJZ@1224|Proteobacteria,1SGEM@1236|Gammaproteobacteria,1XMQP@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF2835) - - - - - - - - - - - - DUF2835 k141_28253_1 218284.CCDN010000005_gene3288 8.53e-98 288.0 COG4862@1|root,COG4862@2|Bacteria,1UZ7D@1239|Firmicutes,4HDV3@91061|Bacilli,1ZAV4@1386|Bacillus 91061|Bacilli NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC mecA GO:0007154,GO:0008150,GO:0009292,GO:0009294,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0044764,GO:0050896,GO:0051704,GO:0051716,GO:0071496 - ko:K16511 - - - - ko00000 - - - MecA k141_10650_2 218284.CCDN010000008_gene4259 6.35e-95 280.0 COG0671@1|root,COG0671@2|Bacteria,1V2ZH@1239|Firmicutes,4HMGP@91061|Bacilli,1ZRR2@1386|Bacillus 91061|Bacilli I PAP2 superfamily - - - - - - - - - - - - PAP2,PAP2_3 k141_33144_1 218284.CCDN010000006_gene3568 8.8e-204 575.0 COG3227@1|root,COG3227@2|Bacteria,1TP08@1239|Firmicutes,4H9S6@91061|Bacilli,1ZCEP@1386|Bacillus 91061|Bacilli E Peptidase M4 nprE GO:0005575,GO:0005576 3.4.24.28 ko:K01400 - - - - ko00000,ko01000,ko01002 - - - FTP,PPC,PepSY,Peptidase_M4,Peptidase_M4_C k141_36539_1 218284.CCDN010000001_gene1545 2.58e-83 246.0 COG2940@1|root,COG2940@2|Bacteria,1V4EX@1239|Firmicutes,4HH4C@91061|Bacilli,1ZGBM@1386|Bacillus 91061|Bacilli S COG2940 Proteins containing SET domain - - - ko:K07117 - - - - ko00000 - - - SET k141_36539_2 218284.CCDN010000001_gene1546 1.69e-115 337.0 28I6D@1|root,2Z89E@2|Bacteria,1TQNW@1239|Firmicutes,4HB4A@91061|Bacilli,1ZB51@1386|Bacillus 91061|Bacilli S EcsC protein family - - - - - - - - - - - - EcsC k141_34415_1 1453501.JELR01000001_gene2918 3.69e-135 395.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,469RZ@72275|Alteromonadaceae 1236|Gammaproteobacteria C Aldehyde dehydrogenase family - - 1.2.1.3,1.2.1.71,1.2.1.9 ko:K00128,ko:K00131,ko:K06447 ko00010,ko00030,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130,map01200 M00135,M00308,M00633 R00264,R00631,R00710,R00904,R01058,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05049,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_10651_1 218284.CCDN010000001_gene1828 3.38e-63 207.0 COG0621@1|root,COG0621@2|Bacteria,1TNYN@1239|Firmicutes,4HAAS@91061|Bacilli,1ZBMF@1386|Bacillus 91061|Bacilli J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine miaB GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035597,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360 2.8.4.3 ko:K06168 - - R10645,R10646,R10647 RC00003,RC00980,RC03221,RC03222 ko00000,ko01000,ko03016 - - - Radical_SAM,TRAM,UPF0004 k141_3424_1 218284.CCDN010000007_gene3929 3e-121 351.0 28M5R@1|root,2ZAJF@2|Bacteria,1UX0B@1239|Firmicutes,4HFIY@91061|Bacilli,1ZH7V@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF4230) - - - - - - - - - - - - DUF4230 k141_34416_1 218284.CCDN010000007_gene3810 4.15e-106 324.0 COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,4H9RZ@91061|Bacilli,1ZBEA@1386|Bacillus 91061|Bacilli NT chemotaxis protein mcpC GO:0005575,GO:0005623,GO:0005886,GO:0006935,GO:0008150,GO:0009605,GO:0016020,GO:0040011,GO:0042221,GO:0042330,GO:0044464,GO:0050896,GO:0050918,GO:0071944 - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal,dCache_1 k141_33145_1 218284.CCDN010000001_gene276 1.52e-128 377.0 COG1757@1|root,COG1757@2|Bacteria,1TQ3B@1239|Firmicutes,4HA18@91061|Bacilli,1ZBQN@1386|Bacillus 91061|Bacilli C Na H antiporter nhaC_2 - - ko:K03315 - - - - ko00000,ko02000 2.A.35 - - Na_H_antiporter k141_17713_2 1279017.AQYJ01000027_gene1806 3.54e-303 838.0 COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,1RMH1@1236|Gammaproteobacteria,46553@72275|Alteromonadaceae 1236|Gammaproteobacteria U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins yidC GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0031224,GO:0031226,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051205,GO:0051234,GO:0051259,GO:0051260,GO:0051641,GO:0061024,GO:0065003,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150 - ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 - - 60KD_IMP,YidC_periplas k141_17713_4 1453501.JELR01000002_gene1117 9.59e-53 171.0 COG0594@1|root,COG0594@2|Bacteria,1MZQE@1224|Proteobacteria,1S90M@1236|Gammaproteobacteria,468AM@72275|Alteromonadaceae 1236|Gammaproteobacteria J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme rnpA GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031974,GO:0031981,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 ko:K03536 - - - - ko00000,ko01000,ko03016 - - - Ribonuclease_P k141_17713_6 1134474.O59_000509 2.5e-29 121.0 COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,1RNHP@1236|Gammaproteobacteria,1FGNR@10|Cellvibrio 1236|Gammaproteobacteria L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids dnaA GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006275,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010556,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1901576,GO:1990837,GO:2000112 - ko:K02313 ko02020,ko04112,map02020,map04112 - - - ko00000,ko00001,ko03032,ko03036 - - - Bac_DnaA,Bac_DnaA_C,DnaA_N k141_34417_1 218284.CCDN010000001_gene1513 5.51e-73 240.0 COG1112@1|root,COG1112@2|Bacteria,1UNF1@1239|Firmicutes,4IPKF@91061|Bacilli,1ZDR8@1386|Bacillus 91061|Bacilli L COG1112 Superfamily I DNA and RNA helicases and helicase subunits - - - - - - - - - - - - AAA_11,AAA_12 k141_21210_1 1453501.JELR01000002_gene892 1.09e-248 707.0 COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,1MWVZ@1224|Proteobacteria,1RQBQ@1236|Gammaproteobacteria,466MY@72275|Alteromonadaceae 1236|Gammaproteobacteria KLT Protein tyrosine kinase stk1 - 2.7.11.1 ko:K08282,ko:K11916,ko:K12132 - - - - ko00000,ko01000,ko01001,ko02044 - - - FGE-sulfatase,Pkinase k141_31691_1 1279017.AQYJ01000027_gene1818 2.14e-179 502.0 COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,1RNWJ@1236|Gammaproteobacteria,4655C@72275|Alteromonadaceae 1236|Gammaproteobacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex atpG GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - iSSON_1240.SSON_3886,iYL1228.KPN_04138 ATP-synt k141_31691_2 1042377.AFPJ01000012_gene1328 0.0 949.0 COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,1RP4V@1236|Gammaproteobacteria,464BU@72275|Alteromonadaceae 1236|Gammaproteobacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit atpA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - iSbBS512_1146.SbBS512_E4187 ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N k141_28254_1 323261.Noc_0589 1.92e-86 278.0 COG0398@1|root,COG1249@1|root,COG0398@2|Bacteria,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RQTU@1236|Gammaproteobacteria,1X2Q6@135613|Chromatiales 135613|Chromatiales C SNARE associated Golgi protein - - - - - - - - - - - - Pyr_redox_2,Pyr_redox_dim,SNARE_assoc k141_28254_3 398767.Glov_0141 5.61e-41 140.0 2E92A@1|root,333BE@2|Bacteria,1N8BM@1224|Proteobacteria,4311M@68525|delta/epsilon subdivisions 1224|Proteobacteria - - - - - - - - - - - - - - - k141_21212_1 218284.CCDN010000002_gene1983 2.68e-79 245.0 COG0026@1|root,COG0026@2|Bacteria,1TQCD@1239|Firmicutes,4H9M5@91061|Bacilli,1ZB8P@1386|Bacillus 91061|Bacilli F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) purK GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 6.3.4.18 ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07404 RC01927 ko00000,ko00001,ko00002,ko01000 - - - 2-Hacid_dh_C,ATP-grasp k141_17714_1 1453501.JELR01000001_gene2060 2.91e-22 89.7 COG1555@1|root,COG1555@2|Bacteria,1N6Q3@1224|Proteobacteria,1SC7U@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Competence protein ComEA comEA GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 - ko:K02237 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - HHH_3 k141_31692_1 1453501.JELR01000002_gene783 9.33e-09 56.6 COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,1RQEX@1236|Gammaproteobacteria,463Z7@72275|Alteromonadaceae 1236|Gammaproteobacteria M Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane lptD GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0009279,GO:0009636,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0042221,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0050896,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:1901264 - ko:K04744 - - - - ko00000,ko02000 1.B.42.1 - iG2583_1286.G2583_0058 OstA,OstA_C k141_31692_2 1042377.AFPJ01000044_gene628 1.95e-65 211.0 COG3178@1|root,COG3178@2|Bacteria,1MXCH@1224|Proteobacteria,1RQ1Q@1236|Gammaproteobacteria,466NT@72275|Alteromonadaceae 1236|Gammaproteobacteria S phosphotransferase related to Ser Thr protein kinases - GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006022,GO:0006040,GO:0006082,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 2.7.1.221 ko:K07102 ko00520,ko01100,map00520,map01100 - R08968,R11024 RC00002,RC00078 ko00000,ko00001,ko01000 - - - APH k141_30539_1 1294265.JCM21738_5072 3.28e-61 191.0 COG0457@1|root,COG0457@2|Bacteria,1V1HX@1239|Firmicutes,4HG5V@91061|Bacilli,1ZCPW@1386|Bacillus 91061|Bacilli S COG0457 FOG TPR repeat yrrB - - - - - - - - - - - TPR_1,TPR_16,TPR_2,TPR_6,TPR_8 k141_29706_2 1485545.JQLW01000005_gene1179 2.12e-88 276.0 28HPH@1|root,2Z7XH@2|Bacteria,1Q80I@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_8064_1 1046714.AMRX01000006_gene3170 2.72e-45 163.0 COG1404@1|root,COG1404@2|Bacteria,1MVE6@1224|Proteobacteria,1RPCA@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Subtilase family - - - - - - - - - - - - Peptidase_S8 k141_8064_2 243277.VC_0182 1.33e-69 213.0 2E1FE@1|root,32WU3@2|Bacteria,1MZHU@1224|Proteobacteria,1S9S3@1236|Gammaproteobacteria,1XXS3@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_8064_3 243277.VC_0183 0.0 1097.0 COG0582@1|root,COG0582@2|Bacteria,1R9JZ@1224|Proteobacteria,1RY18@1236|Gammaproteobacteria,1XW77@135623|Vibrionales 135623|Vibrionales L viral genome integration into host DNA - - - - - - - - - - - - - k141_3426_1 1117379.BABA_00565 1.18e-160 460.0 COG3191@1|root,COG3191@2|Bacteria,1TQHA@1239|Firmicutes,4HAZM@91061|Bacilli,1ZDRB@1386|Bacillus 91061|Bacilli EQ Peptidase family S58 - - 3.4.11.19 ko:K01266 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S58 k141_2210_2 1136163.M565_ctg1P1344 1.1e-51 165.0 2AH3Y@1|root,317DF@2|Bacteria,1QM4C@1224|Proteobacteria,1TJC4@1236|Gammaproteobacteria,1Y0ZT@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_36540_1 1279017.AQYJ01000028_gene2469 7.93e-100 297.0 COG3047@1|root,COG3047@2|Bacteria,1NUZJ@1224|Proteobacteria,1RRRC@1236|Gammaproteobacteria,467CK@72275|Alteromonadaceae 1236|Gammaproteobacteria M Outer membrane protein W ompW - - ko:K07275 - - - - ko00000 - - - OmpW k141_36540_2 1279017.AQYJ01000028_gene2369 1.12e-148 420.0 COG0518@1|root,COG0518@2|Bacteria,1MV9U@1224|Proteobacteria,1S2MK@1236|Gammaproteobacteria,467Q4@72275|Alteromonadaceae 1236|Gammaproteobacteria F COG0518 GMP synthase - Glutamine amidotransferase domain - - 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase k141_36540_3 1453501.JELR01000002_gene589 2.11e-98 289.0 COG1225@1|root,COG1225@2|Bacteria,1R9YF@1224|Proteobacteria,1S37E@1236|Gammaproteobacteria,46DC6@72275|Alteromonadaceae 1236|Gammaproteobacteria O Redoxin - - - - - - - - - - - - AhpC-TSA k141_28256_2 218284.CCDN010000001_gene1188 2.36e-14 69.7 2CFTY@1|root,336V6@2|Bacteria,1VH1W@1239|Firmicutes,4HQI3@91061|Bacilli,1ZH6G@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_15257_2 218284.CCDN010000001_gene1102 3.42e-81 251.0 COG0240@1|root,COG0240@2|Bacteria,1TQ5P@1239|Firmicutes,4HAXW@91061|Bacilli,1ZCHQ@1386|Bacillus 91061|Bacilli I Glycerol-3-phosphate dehydrogenase gpsA GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0047952,GO:0055114 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 - R00842,R00844 RC00029 ko00000,ko00001,ko01000 - - - NAD_Gly3P_dh_C,NAD_Gly3P_dh_N k141_2211_1 997346.HMPREF9374_2956 2.6e-46 160.0 COG1526@1|root,COG1526@2|Bacteria,1TU8R@1239|Firmicutes,4HAY8@91061|Bacilli,27D3Y@186824|Thermoactinomycetaceae 91061|Bacilli C FdhD/NarQ family fdhD - - ko:K02379 - - - - ko00000 - - - FdhD-NarQ k141_36541_1 1294265.JCM21738_2596 6.8e-24 95.5 28NT3@1|root,2ZBRV@2|Bacteria,1V1C2@1239|Firmicutes,4HFYQ@91061|Bacilli,1ZFIE@1386|Bacillus 91061|Bacilli S YwiC-like protein - - - - - - - - - - - - YwiC k141_36541_2 1078085.HMPREF1210_02017 3.09e-31 115.0 28K3D@1|root,2Z9SI@2|Bacteria,1UZKH@1239|Firmicutes,4HDH6@91061|Bacilli,26F03@186818|Planococcaceae 91061|Bacilli S MEDS: MEthanogen/methylotroph, DcmR Sensory domain - - - - - - - - - - - - MEDS k141_31693_1 935837.JAEK01000020_gene592 2.66e-119 360.0 COG3437@1|root,COG3437@2|Bacteria,1TQ0S@1239|Firmicutes,4HEM3@91061|Bacilli,1ZDPH@1386|Bacillus 91061|Bacilli KT HD domain M1-580 - - - - - - - - - - - GGDEF,HD,HD_5,PAS_3,PAS_9 k141_4619_1 218284.CCDN010000001_gene1358 1.22e-195 553.0 COG0488@1|root,COG0488@2|Bacteria,1TPW0@1239|Firmicutes,4HATH@91061|Bacilli,1ZBVV@1386|Bacillus 91061|Bacilli S COG0488 ATPase components of ABC transporters with duplicated ATPase domains ykpA - - - - - - - - - - - ABC_tran,ABC_tran_Xtn k141_4619_2 1487921.DP68_07405 1.74e-07 55.5 COG1633@1|root,COG1633@2|Bacteria,1V860@1239|Firmicutes,24ERW@186801|Clostridia,36EYA@31979|Clostridiaceae 186801|Clostridia G PFAM Rubrerythrin - - - - - - - - - - - - Rubrerythrin k141_16556_2 1116375.VEJY3_22241 0.0 1127.0 COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,1RNVR@1236|Gammaproteobacteria,1XV69@135623|Vibrionales 135623|Vibrionales P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family kefC - - ko:K03455,ko:K11745 - - - - ko00000,ko02000 2.A.37,2.A.37.1.1 - - Na_H_Exchanger,TrkA_N k141_16556_3 223926.28808631 1.47e-136 387.0 COG2249@1|root,COG2249@2|Bacteria,1MXFT@1224|Proteobacteria,1RMVS@1236|Gammaproteobacteria,1XU4N@135623|Vibrionales 135623|Vibrionales S NADPH-quinone reductase (modulator of drug activity B) ywrO - - - - - - - - - - - Flavodoxin_2 k141_16556_4 1219076.N646_4693 8.7e-94 274.0 COG0589@1|root,COG0589@2|Bacteria,1MV6Y@1224|Proteobacteria,1RQQ7@1236|Gammaproteobacteria,1XX6F@135623|Vibrionales 135623|Vibrionales T COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - - - - - - - - - - Usp k141_16556_5 223926.28808635 9.45e-153 433.0 28PXN@1|root,2ZCHK@2|Bacteria,1R71P@1224|Proteobacteria,1S2DY@1236|Gammaproteobacteria,1XUGY@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_33188_1 326423.RBAM_011690 6.37e-11 58.9 COG2104@1|root,COG2104@2|Bacteria,1VKB4@1239|Firmicutes,4HR3T@91061|Bacilli,1ZJY0@1386|Bacillus 91061|Bacilli H Thiamine biosynthesis thiS - - ko:K03154 ko04122,map04122 - - - ko00000,ko00001 - - - ThiS k141_37885_1 1042377.AFPJ01000021_gene2117 4.43e-87 275.0 COG2244@1|root,COG2244@2|Bacteria 2|Bacteria S polysaccharide biosynthetic process - - - - - - - - - - - - MatE,Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C k141_37885_2 1453501.JELR01000001_gene3138 8.97e-191 534.0 COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,1RMZ5@1236|Gammaproteobacteria,4653E@72275|Alteromonadaceae 1236|Gammaproteobacteria M Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)- (lauroyl)-lipid IV(A) lpxL GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006082,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0006950,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008951,GO:0009058,GO:0009245,GO:0009247,GO:0009266,GO:0009311,GO:0009312,GO:0009409,GO:0009628,GO:0009987,GO:0016020,GO:0016051,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0019752,GO:0036103,GO:0036104,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046467,GO:0046493,GO:0050896,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.241,2.3.1.242 ko:K02517,ko:K12974 ko00540,ko01100,map00540,map01100 M00060 R05146,R10906 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005 - - iEC042_1314.EC042_2597,iSF_1195.SF1061,iS_1188.S1138,iYL1228.KPN_01068 Lip_A_acyltrans k141_37885_3 1279017.AQYJ01000022_gene2713 1.34e-180 506.0 COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,1RNH9@1236|Gammaproteobacteria,464AC@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) dapA GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008840,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0019877,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - iECP_1309.ECP_2492,iJN746.PP_1237,iYL1228.KPN_02812 DHDPS k141_37885_4 1453501.JELR01000001_gene3136 6.51e-199 560.0 COG3317@1|root,COG3317@2|Bacteria,1N670@1224|Proteobacteria,1RZVF@1236|Gammaproteobacteria,46CQH@72275|Alteromonadaceae 1236|Gammaproteobacteria M NlpB/DapX lipoprotein bamC - - ko:K07287 - - - - ko00000,ko02000 1.B.33.1 - - Lipoprotein_18 k141_4656_1 1453501.JELR01000002_gene177 1.19e-125 369.0 COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,1RNQ8@1236|Gammaproteobacteria,463YI@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) hemA GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006536,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008883,GO:0009058,GO:0009064,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019353,GO:0019438,GO:0019752,GO:0033013,GO:0033014,GO:0033526,GO:0034641,GO:0042168,GO:0042440,GO:0042802,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.2.1.70 ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R04109 RC00055,RC00149 ko00000,ko00001,ko00002,ko01000 - - iECNA114_1301.ECNA114_1375,iECSF_1327.ECSF_1186,iUTI89_1310.UTI89_C1404 GlutR_N,GlutR_dimer,Shikimate_DH k141_21264_1 1453501.JELR01000002_gene1154 3.54e-148 434.0 COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,1RNVR@1236|Gammaproteobacteria,465MZ@72275|Alteromonadaceae 1236|Gammaproteobacteria P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family kefC - - ko:K03455,ko:K11745,ko:K11747 - - - - ko00000,ko02000 2.A.37,2.A.37.1.1,2.A.37.1.2 - - Na_H_Exchanger,TrkA_N k141_2255_1 42565.FP66_12420 1.53e-13 69.3 COG0697@1|root,COG0697@2|Bacteria,1MWMC@1224|Proteobacteria,1RQST@1236|Gammaproteobacteria,1XJ8R@135619|Oceanospirillales 135619|Oceanospirillales EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - - - - - - - - - - EamA k141_14271_1 1294265.JCM21738_3833 5.64e-34 127.0 COG0501@1|root,COG0501@2|Bacteria,1TRQE@1239|Firmicutes,4HD5G@91061|Bacilli,1ZC4F@1386|Bacillus 91061|Bacilli O Peptidase M48 yhfN GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0070011,GO:0071586,GO:0071704,GO:0080120,GO:0140096,GO:1901564 - - - - - - - - - - Peptidase_M48,Peptidase_M48_N k141_32104_1 351607.Acel_1394 4.96e-157 471.0 COG1048@1|root,COG1048@2|Bacteria,2GJD5@201174|Actinobacteria,4ESAU@85013|Frankiales 201174|Actinobacteria C Aconitate hydratase 1 acnA - 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_C k141_30917_2 1042377.AFPJ01000034_gene2324 4.84e-53 167.0 COG1925@1|root,COG1925@2|Bacteria,1N6RM@1224|Proteobacteria,1SCXX@1236|Gammaproteobacteria,468BC@72275|Alteromonadaceae 1236|Gammaproteobacteria G COG1925 Phosphotransferase system, HPr-related proteins ptsO GO:0003674,GO:0003824,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006808,GO:0006810,GO:0008150,GO:0008152,GO:0008643,GO:0009401,GO:0009987,GO:0010033,GO:0010243,GO:0016310,GO:0016740,GO:0016772,GO:0019538,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050896,GO:0051179,GO:0051234,GO:0065007,GO:0071702,GO:0071704,GO:1901564,GO:1901698 - ko:K08485,ko:K11189 ko02060,map02060 - - - ko00000,ko00001,ko02000 4.A.2.1 - - PTS-HPr k141_30917_3 1453501.JELR01000001_gene3091 7.14e-15 73.2 COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,1RNE4@1236|Gammaproteobacteria,4641S@72275|Alteromonadaceae 1236|Gammaproteobacteria P Acts as a magnesium transporter mgtE - - ko:K06213 - - - - ko00000,ko02000 1.A.26.1 - - CBS,MgtE,MgtE_N k141_23785_1 572477.Alvin_0886 9.61e-78 237.0 COG4149@1|root,COG4149@2|Bacteria,1MUXR@1224|Proteobacteria,1RRDV@1236|Gammaproteobacteria,1WWGA@135613|Chromatiales 135613|Chromatiales P TIGRFAM Molybdate ABC transporter - - - ko:K02018 ko02010,map02010 M00189 - - ko00000,ko00001,ko00002,ko02000 3.A.1.8 - - BPD_transp_1 k141_23785_2 644801.Psest_3001 7.01e-32 122.0 COG4148@1|root,COG4148@2|Bacteria,1MU8K@1224|Proteobacteria,1RQCV@1236|Gammaproteobacteria,1Z0IP@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria P Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system modC GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015098,GO:0015103,GO:0015318,GO:0015399,GO:0015405,GO:0015412,GO:0015689,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0042623,GO:0042626,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0099133 3.6.3.29 ko:K02017 ko02010,map02010 M00189 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.8 - - ABC_tran,TOBE k141_22593_1 665959.HMPREF1013_04881 1.05e-110 327.0 COG4927@1|root,COG4927@2|Bacteria,1TQGX@1239|Firmicutes,4HATV@91061|Bacilli,1ZC2P@1386|Bacillus 91061|Bacilli S Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase - - - - - - - - - - - - AAT k141_26160_1 1279017.AQYJ01000028_gene2158 1.22e-64 207.0 COG0212@1|root,COG0212@2|Bacteria,1MZG0@1224|Proteobacteria,1S612@1236|Gammaproteobacteria,467AN@72275|Alteromonadaceae 1236|Gammaproteobacteria H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family ygfA GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0022611,GO:0030272,GO:0032502,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.2 ko:K01934 ko00670,ko01100,map00670,map01100 - R02301 RC00183 ko00000,ko00001,ko01000 - - iECABU_c1320.ECABU_c31940,iECOK1_1307.ECOK1_3298,iECSF_1327.ECSF_2705,iUTI89_1310.UTI89_C3298 5-FTHF_cyc-lig k141_24969_2 218284.CCDN010000005_gene3292 2.98e-152 431.0 COG2761@1|root,COG2761@2|Bacteria,1TQ8K@1239|Firmicutes,4HAI8@91061|Bacilli,1ZATS@1386|Bacillus 91061|Bacilli Q dithiol-disulfide isomerase involved in polyketide biosynthesis yjbH - - - - - - - - - - - Thioredoxin_5 k141_4759_1 218284.CCDN010000006_gene3647 6.53e-07 49.7 COG0370@1|root,COG0370@2|Bacteria,1TQT3@1239|Firmicutes,4HAIZ@91061|Bacilli,1ZAYP@1386|Bacillus 91061|Bacilli P COG0370 Fe2 transport system protein B yvoD - - - - - - - - - - - Gate k141_4759_2 218284.CCDN010000006_gene3648 2.44e-154 438.0 COG0682@1|root,COG0682@2|Bacteria,1TPAK@1239|Firmicutes,4HAT0@91061|Bacilli,1ZAR8@1386|Bacillus 91061|Bacilli M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins lgt GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016757,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:0140096,GO:1901564 - ko:K13292 - - - - ko00000,ko01000 - - - LGT k141_7138_1 1042377.AFPJ01000052_gene1555 2.63e-63 215.0 COG3188@1|root,COG3188@2|Bacteria,1PTRC@1224|Proteobacteria,1S047@1236|Gammaproteobacteria 1236|Gammaproteobacteria NU E-set like domain cblC - - - - - - - - - - - CooC_C,TcfC,Usher_TcfC k141_34483_1 218284.CCDN010000010_gene4390 1.7e-70 218.0 COG1211@1|root,COG1211@2|Bacteria,1V3M7@1239|Firmicutes,4HH2N@91061|Bacilli,1ZCWR@1386|Bacillus 91061|Bacilli I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) ispD GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05633 RC00002 ko00000,ko00001,ko00002,ko01000 - - - IspD k141_22594_1 218284.CCDN010000002_gene2775 2.71e-95 291.0 COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,4HBR4@91061|Bacilli,1ZB39@1386|Bacillus 91061|Bacilli JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes dbpA GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 3.6.4.13 ko:K05592 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,DbpA,Helicase_C k141_3572_1 406124.ACPC01000009_gene1464 1.19e-88 274.0 COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HACS@91061|Bacilli,1ZATG@1386|Bacillus 91061|Bacilli IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - - - - - - - - - - AMP-binding,AMP-binding_C k141_20215_1 373903.Hore_04180 1.52e-140 421.0 COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,24932@186801|Clostridia,3WBFC@53433|Halanaerobiales 186801|Clostridia G Glycosyl hydrolase family 3 C-terminal domain - - 3.2.1.21 ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 - R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - GH3 - CBM_6,Glyco_hydro_3,Glyco_hydro_3_C k141_20215_2 1042377.AFPJ01000008_gene1960 6.89e-162 467.0 COG2273@1|root,COG2273@2|Bacteria,1NFHX@1224|Proteobacteria,1RRPK@1236|Gammaproteobacteria,463ZT@72275|Alteromonadaceae 1236|Gammaproteobacteria G Beta-glucanase Beta-glucan synthetase - - - - - - - - - - - - Glyco_hydro_16 k141_20215_3 318167.Sfri_0801 7.13e-19 87.0 COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,1RQRP@1236|Gammaproteobacteria,2QB0C@267890|Shewanellaceae 1236|Gammaproteobacteria Q Amidohydrolase family - - - - - - - - - - - - Amidohydro_1 k141_29725_1 1380391.JIAS01000018_gene899 1.89e-20 91.7 COG4133@1|root,COG4133@2|Bacteria,1MZPC@1224|Proteobacteria,2TVBT@28211|Alphaproteobacteria,2JRQJ@204441|Rhodospirillales 204441|Rhodospirillales O once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system ccmA - 3.6.3.41 ko:K02193 ko02010,map02010 M00259 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.107 - - ABC_tran k141_29725_3 1044.EH31_06060 8.69e-11 69.3 COG0614@1|root,COG0614@2|Bacteria,1R5ZN@1224|Proteobacteria,2U3W4@28211|Alphaproteobacteria,2K52F@204457|Sphingomonadales 204457|Sphingomonadales P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component - - - - - - - - - - - - Peripla_BP_2 k141_29725_4 1279017.AQYJ01000028_gene2362 5.33e-304 832.0 COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,1RN2E@1236|Gammaproteobacteria,4659K@72275|Alteromonadaceae 1236|Gammaproteobacteria O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function radA GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - ko:K04485 - - - - ko00000,ko03400 - - - AAA_25,ATPase,ChlI k141_29725_5 1380358.JADJ01000001_gene1301 1.3e-18 84.3 28PDJ@1|root,2ZC5G@2|Bacteria,1RCPJ@1224|Proteobacteria,1S3C7@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_29725_6 1547437.LL06_01585 5.81e-111 325.0 COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,2TSU8@28211|Alphaproteobacteria 28211|Alphaproteobacteria S polyphosphate kinase - - 2.7.4.1 ko:K22468 ko00190,ko03018,map00190,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - PPK2 k141_16646_1 218284.CCDN010000010_gene4346 1.39e-170 484.0 COG0201@1|root,COG0201@2|Bacteria,1TPHB@1239|Firmicutes,4HAWH@91061|Bacilli,1ZCEG@1386|Bacillus 91061|Bacilli U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently secY GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5 - - SecY k141_16646_2 218284.CCDN010000010_gene4345 2.55e-151 425.0 COG0563@1|root,COG0563@2|Bacteria,1TP27@1239|Firmicutes,4HA89@91061|Bacilli,1ZBYM@1386|Bacillus 91061|Bacilli F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism adk GO:0003674,GO:0003824,GO:0004017,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ADK,ADK_lid k141_17836_1 218284.CCDN010000006_gene3526 1.84e-110 325.0 COG0609@1|root,COG0609@2|Bacteria,1TP13@1239|Firmicutes,4HAW8@91061|Bacilli,1ZQ8X@1386|Bacillus 91061|Bacilli P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily yfiZ - - ko:K02015 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - iYO844.BSU08450 FecCD k141_17836_2 218284.CCDN010000006_gene3525 1.18e-153 439.0 COG0609@1|root,COG0609@2|Bacteria,1TPX6@1239|Firmicutes,4HAM8@91061|Bacilli,1ZAU0@1386|Bacillus 91061|Bacilli P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily yfhA - - ko:K02015 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - FecCD k141_13085_1 1453501.JELR01000002_gene1489 2.62e-249 709.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MUNK@1224|Proteobacteria,1RN9S@1236|Gammaproteobacteria,469NI@72275|Alteromonadaceae 1236|Gammaproteobacteria P receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_14272_2 997296.PB1_06047 2.31e-62 203.0 COG0609@1|root,COG0609@2|Bacteria,1TPX6@1239|Firmicutes,4HAUK@91061|Bacilli,1ZD7V@1386|Bacillus 91061|Bacilli P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily btuC - - ko:K02015 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - iYO844.BSU33170 FecCD k141_8333_1 1453501.JELR01000002_gene1090 4.03e-55 179.0 COG0169@1|root,COG0169@2|Bacteria,1MVH4@1224|Proteobacteria,1RPB7@1236|Gammaproteobacteria,4647Q@72275|Alteromonadaceae 1236|Gammaproteobacteria E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) aroE GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_3165,iECOK1_1307.ECOK1_3701,iECS88_1305.ECS88_3669,iECUMN_1333.ECUMN_3755,iSBO_1134.SBO_3275,iUMN146_1321.UM146_16315,iUTI89_1310.UTI89_C3726 Shikimate_DH,Shikimate_dh_N k141_8333_3 1453501.JELR01000002_gene1092 4.18e-26 102.0 COG0408@1|root,COG0408@2|Bacteria,1MWMF@1224|Proteobacteria,1RMM8@1236|Gammaproteobacteria,464YS@72275|Alteromonadaceae 1236|Gammaproteobacteria H Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX hemF GO:0003674,GO:0003824,GO:0004109,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0016634,GO:0018130,GO:0019438,GO:0030145,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046906,GO:0046914,GO:0046983,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.3.3.3 ko:K00228 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03220 RC00884 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b2436,iBWG_1329.BWG_2198,iECDH10B_1368.ECDH10B_2601,iECDH1ME8569_1439.ECDH1ME8569_2370,iETEC_1333.ETEC_2549,iEcDH1_1363.EcDH1_1225,iEcHS_1320.EcHS_A2573,iEcolC_1368.EcolC_1243,iJO1366.b2436,iJR904.b2436,iY75_1357.Y75_RS12760 Coprogen_oxidas k141_4760_1 203122.Sde_2428 1.58e-19 87.0 COG0418@1|root,COG0418@2|Bacteria,1MUYP@1224|Proteobacteria,1RNEN@1236|Gammaproteobacteria,4642S@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate pyrC GO:0003674,GO:0003824,GO:0004151,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - iSBO_1134.SBO_2002,iYL1228.KPN_01074 Amidohydro_1 k141_21409_1 218284.CCDN010000005_gene3291 1.77e-69 226.0 COG1164@1|root,COG1164@2|Bacteria,1TP4P@1239|Firmicutes,4HA7X@91061|Bacilli,1ZCHA@1386|Bacillus 91061|Bacilli E oligoendopeptidase F pepF GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - ko:K08602 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M3,Peptidase_M3_N k141_5952_1 1294265.JCM21738_3904 1.44e-137 404.0 COG1680@1|root,COG1680@2|Bacteria,1U828@1239|Firmicutes,4HA0Q@91061|Bacilli,1ZBJ0@1386|Bacillus 91061|Bacilli V Belongs to the UPF0214 family estB - - - - - - - - - - - Beta-lactamase,Peptidase_M6 k141_5952_2 1294265.JCM21738_3905 7.82e-12 66.2 COG1472@1|root,COG5492@1|root,COG1472@2|Bacteria,COG5492@2|Bacteria,1TP63@1239|Firmicutes,4HBDB@91061|Bacilli,1ZCGR@1386|Bacillus 91061|Bacilli G Belongs to the glycosyl hydrolase 3 family ybbD - 3.2.1.52 ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 M00628 R00022,R05963,R07809,R07810,R10831 RC00049 ko00000,ko00001,ko00002,ko01000 - - - Big_2,Glyco_hydro_3,Glyco_hydro_3_C,Gram_pos_anchor,SLH k141_3573_1 42565.FP66_00610 3.48e-39 142.0 COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,1RPT8@1236|Gammaproteobacteria,1XIGU@135619|Oceanospirillales 135619|Oceanospirillales K transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_27351_1 218284.CCDN010000001_gene1851 2.92e-102 312.0 COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1TSSC@1239|Firmicutes,4HA8C@91061|Bacilli,1ZBA6@1386|Bacillus 91061|Bacilli C COG1014 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, gamma subunit korA - 1.2.7.11,1.2.7.3 ko:K00174 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - PFOR_II,POR,POR_N k141_15461_1 218284.CCDN010000003_gene2981 1.37e-185 517.0 COG0503@1|root,COG0503@2|Bacteria,1TPN9@1239|Firmicutes,4HB8I@91061|Bacilli,1ZAW9@1386|Bacillus 91061|Bacilli F pur operon repressor purR - - ko:K09685 - - - - ko00000,ko03000 - - - Pribosyltran,PuR_N k141_15461_2 218284.CCDN010000003_gene2982 7.27e-78 232.0 COG0251@1|root,COG0251@2|Bacteria,1V6HG@1239|Firmicutes,4HKEF@91061|Bacilli,1ZG9Q@1386|Bacillus 91061|Bacilli J translation initiation inhibitor, yjgF family yabJ GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0019239,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046360,GO:0046361,GO:0046394,GO:0046459,GO:0051790,GO:0071704,GO:0072330,GO:1901576 3.5.99.10 ko:K09022 - - R11098,R11099 RC03275,RC03354 ko00000,ko01000 - - - Ribonuc_L-PSP k141_26161_1 1294265.JCM21738_2447 9.21e-114 330.0 COG1191@1|root,COG1191@2|Bacteria,1TP3Q@1239|Firmicutes,4HBIW@91061|Bacilli,1ZBAP@1386|Bacillus 91061|Bacilli K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released sigB GO:0000988,GO:0000990,GO:0003674,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043254,GO:0043620,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - ko:K03090 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r3,Sigma70_r4 k141_26161_2 1294265.JCM21738_2446 2.64e-100 291.0 COG2172@1|root,COG2172@2|Bacteria,1V1IA@1239|Firmicutes,4HFPF@91061|Bacilli,1ZF6G@1386|Bacillus 91061|Bacilli T Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B) rsbW GO:0000988,GO:0000989,GO:0003674,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 2.7.11.1 ko:K04757 - - - - ko00000,ko01000,ko01001,ko03021 - - - HATPase_c_2 k141_22595_1 1294265.JCM21738_4172 3.25e-105 304.0 COG0835@1|root,COG0835@2|Bacteria,1V428@1239|Firmicutes,4HI77@91061|Bacilli,1ZFHY@1386|Bacillus 91061|Bacilli NT COG0835 Chemotaxis signal transduction protein - - - ko:K03408 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - CheW k141_8334_1 1123518.ARWI01000001_gene487 1.46e-45 164.0 COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,45ZUA@72273|Thiotrichales 72273|Thiotrichales M gamma-glutamyltranspeptidase - - 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept k141_21410_1 218284.CCDN010000002_gene2090 9.3e-116 335.0 COG1024@1|root,COG1024@2|Bacteria,1TQ2V@1239|Firmicutes,4HBT0@91061|Bacilli,1ZE3C@1386|Bacillus 91061|Bacilli I Belongs to the enoyl-CoA hydratase isomerase family paaG - 5.3.3.18 ko:K15866 ko00360,ko01120,map00360,map01120 - R09837,R09839 RC00004,RC00326,RC02689,RC03003 ko00000,ko00001,ko01000 - - - ECH_1 k141_23788_1 743719.PaelaDRAFT_2989 5.65e-13 68.9 COG0671@1|root,COG0671@2|Bacteria,1V33Y@1239|Firmicutes,4HGAT@91061|Bacilli,26T9V@186822|Paenibacillaceae 91061|Bacilli I Membrane-associated phospholipid phosphatase - - 3.6.1.27 ko:K19302 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - PAP2 k141_4762_1 1453501.JELR01000001_gene2037 5.29e-114 337.0 COG3746@1|root,COG3746@2|Bacteria,1RG6T@1224|Proteobacteria,1S412@1236|Gammaproteobacteria,468U6@72275|Alteromonadaceae 1236|Gammaproteobacteria P Phosphate-selective porin O and P oprO - - ko:K07221 - - - - ko00000,ko02000 1.B.5.1 - - Porin_O_P k141_15463_1 218284.CCDN010000008_gene4214 3.17e-23 104.0 COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,4HA1S@91061|Bacilli,1ZAYY@1386|Bacillus 91061|Bacilli D Belongs to the FtsK SpoIIIE SftA family sftA - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_SpoIIIE,Ftsk_gamma k141_22596_1 1211814.CAPG01000064_gene3018 9.08e-44 144.0 COG0254@1|root,COG0254@2|Bacteria,1VEGU@1239|Firmicutes,4HNQF@91061|Bacilli,1ZQBD@1386|Bacillus 91061|Bacilli J Binds the 23S rRNA rpmE - - ko:K02909 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L31 k141_7139_2 218284.CCDN010000007_gene3795 2.38e-129 369.0 COG1847@1|root,COG1847@2|Bacteria,1V3IN@1239|Firmicutes,4HHHU@91061|Bacilli,1ZDGU@1386|Bacillus 91061|Bacilli S single-stranded nucleic acid binding R3H jag - - ko:K06346 - - - - ko00000 - - - Jag_N,KH_4,R3H k141_21411_1 1279017.AQYJ01000027_gene1785 5.13e-82 257.0 COG1680@1|root,COG1680@2|Bacteria,1MZQ3@1224|Proteobacteria,1RWRY@1236|Gammaproteobacteria,466A7@72275|Alteromonadaceae 1236|Gammaproteobacteria V Beta-lactamase - - 3.4.16.4 ko:K01286 - - - - ko00000,ko01000 - - - Beta-lactamase k141_8336_1 218284.CCDN010000001_gene38 9.11e-85 255.0 COG1564@1|root,COG1564@2|Bacteria,1VA0W@1239|Firmicutes,4HHS1@91061|Bacilli,1ZD4A@1386|Bacillus 91061|Bacilli H thiamine pyrophosphokinase thiN - 2.7.6.2 ko:K00949 ko00730,ko01100,map00730,map01100 - R00619 RC00002,RC00017 ko00000,ko00001,ko01000 - - - TPK_B1_binding,TPK_catalytic k141_30920_1 935845.JADQ01000024_gene266 6.33e-55 189.0 COG2268@1|root,COG2268@2|Bacteria,1TQDT@1239|Firmicutes,4HA0C@91061|Bacilli,26QNP@186822|Paenibacillaceae 91061|Bacilli S Protein conserved in bacteria yuaG - - ko:K07192 ko04910,map04910 - - - ko00000,ko00001,ko03036,ko04131,ko04147 - - - Band_7,Flot k141_24970_3 1279017.AQYJ01000027_gene1901 6.59e-155 439.0 COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,1RP3J@1236|Gammaproteobacteria,464SQ@72275|Alteromonadaceae 1236|Gammaproteobacteria L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates fpg GO:0000702,GO:0000703,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003824,GO:0003906,GO:0004518,GO:0004519,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008270,GO:0008534,GO:0009987,GO:0016787,GO:0016788,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.2.2.23,4.2.99.18 ko:K10563 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Fapy_DNA_glyco,H2TH,zf-FPG_IleRS k141_24970_5 1453501.JELR01000002_gene1222 6.2e-06 47.4 COG1495@1|root,COG1495@2|Bacteria,1RKPG@1224|Proteobacteria,1SC4J@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Disulfide bond formation protein DsbB lidJ - - - - - - - - - - - DsbB k141_11894_1 1196031.ALEG01000039_gene1151 3.83e-60 207.0 COG3857@1|root,COG3857@2|Bacteria,1TQJW@1239|Firmicutes,4HAY6@91061|Bacilli,1ZC70@1386|Bacillus 91061|Bacilli L ATP-dependent helicase deoxyribonuclease subunit B rexB GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0004527,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.6.4.12 ko:K16899 - - - - ko00000,ko01000,ko03400 - - - Exonuc_V_gamma,PDDEXK_1,UvrD_C k141_11894_2 1294265.JCM21738_2667 1.99e-46 159.0 COG0477@1|root,COG2814@2|Bacteria,1UXYG@1239|Firmicutes,4HBZB@91061|Bacilli,1ZQ79@1386|Bacillus 91061|Bacilli EGP COG0477 Permeases of the major facilitator superfamily ynfM3 - - - - - - - - - - - MFS_1,Sugar_tr k141_19027_3 218284.CCDN010000001_gene1154 7.04e-57 179.0 2C8E7@1|root,32RKZ@2|Bacteria,1VIES@1239|Firmicutes,4HKFC@91061|Bacilli,1ZITF@1386|Bacillus 91061|Bacilli S Bacterial domain of unknown function (DUF1798) yppE - - - - - - - - - - - DUF1798 k141_19027_4 666686.B1NLA3E_14605 4.75e-06 47.0 2ETMY@1|root,33M5Q@2|Bacteria,1VPZB@1239|Firmicutes,4HR2S@91061|Bacilli,1ZKDZ@1386|Bacillus 91061|Bacilli S YppF-like protein - - - - - - - - - - - - YppF k141_26162_1 218284.CCDN010000002_gene2917 2.69e-73 222.0 COG2259@1|root,COG2259@2|Bacteria,1V4ER@1239|Firmicutes,4HGZN@91061|Bacilli,1ZEVR@1386|Bacillus 91061|Bacilli S DoxX - - 1.8.5.2 ko:K16937 ko00920,ko01120,map00920,map01120 - R07177 - ko00000,ko00001,ko01000 3.D.4.9 - - DoxX k141_10717_3 1274524.BSONL12_01367 4.61e-21 89.0 COG1999@1|root,COG1999@2|Bacteria,1V03J@1239|Firmicutes,4HET3@91061|Bacilli,1ZFJQ@1386|Bacillus 91061|Bacilli S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems ypmQ - - ko:K07152 - - - - ko00000,ko03029 - - - SCO1-SenC k141_11909_1 218284.CCDN010000002_gene2921 1.32e-44 151.0 COG2137@1|root,COG2137@2|Bacteria,1V72V@1239|Firmicutes,4HJ7R@91061|Bacilli,1ZC8N@1386|Bacillus 91061|Bacilli S Modulates RecA activity recX - - ko:K03565 - - - - ko00000,ko03400 - - - RecX k141_3603_1 1279017.AQYJ01000024_gene1022 1.32e-139 417.0 COG1835@1|root,COG1835@2|Bacteria,1MV2W@1224|Proteobacteria,1RQS2@1236|Gammaproteobacteria,465QX@72275|Alteromonadaceae 1236|Gammaproteobacteria I Acyltransferase - - - - - - - - - - - - Acyl_transf_3 k141_3603_2 102125.Xen7305DRAFT_00024850 2e-06 57.8 COG1874@1|root,COG1874@2|Bacteria,1GH6K@1117|Cyanobacteria,3VNCP@52604|Pleurocapsales 1117|Cyanobacteria G Beta-galactosidase - - - - - - - - - - - - - k141_20230_1 218284.CCDN010000002_gene2891 6.3e-84 254.0 COG1120@1|root,COG1120@2|Bacteria,1TP2Q@1239|Firmicutes,4HADG@91061|Bacilli,1ZBMI@1386|Bacillus 91061|Bacilli HP ABC transporter fhuC - 3.6.3.34 ko:K02013 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 - - ABC_tran k141_20230_2 1305836.AXVE01000011_gene1023 1.18e-23 98.2 COG0614@1|root,COG0614@2|Bacteria,1TQMK@1239|Firmicutes,4HBP4@91061|Bacilli,26DKY@186818|Planococcaceae 91061|Bacilli P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component fhuD - - ko:K02016 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - Peripla_BP_2 k141_22615_1 1042377.AFPJ01000009_gene255 1.45e-89 290.0 COG1026@1|root,COG1026@2|Bacteria,1MVDJ@1224|Proteobacteria,1RYNI@1236|Gammaproteobacteria,465V1@72275|Alteromonadaceae 1236|Gammaproteobacteria S Zn-dependent peptidases, insulinase-like - - - ko:K06972 - - - - ko00000,ko01000,ko01002 - - - M16C_assoc,Peptidase_M16,Peptidase_M16_C k141_17858_1 218284.CCDN010000001_gene1390 6.25e-134 390.0 COG1092@1|root,COG1092@2|Bacteria,1TRAJ@1239|Firmicutes,4HAA1@91061|Bacilli,1ZBVG@1386|Bacillus 91061|Bacilli J Methyltransferase ywbD - 2.1.1.191 ko:K06969 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_SAM k141_30937_1 1453501.JELR01000002_gene799 2.43e-117 338.0 COG2236@1|root,COG2236@2|Bacteria,1MXS1@1224|Proteobacteria,1RPSD@1236|Gammaproteobacteria,46742@72275|Alteromonadaceae 1236|Gammaproteobacteria F Phosphoribosyl transferase domain - - - ko:K07101 - - - - ko00000 - - - Pribosyltran k141_4792_1 1380387.JADM01000008_gene987 7.75e-41 144.0 COG1526@1|root,COG1526@2|Bacteria,1NRU0@1224|Proteobacteria,1RNFH@1236|Gammaproteobacteria,1XK16@135619|Oceanospirillales 135619|Oceanospirillales C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH fdhD - - ko:K02379 - - - - ko00000 - - - FdhD-NarQ k141_4792_2 1042377.AFPJ01000007_gene1766 1.17e-194 562.0 COG0243@1|root,COG0243@2|Bacteria,1MU6B@1224|Proteobacteria,1RNXW@1236|Gammaproteobacteria,4651W@72275|Alteromonadaceae 1236|Gammaproteobacteria C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family ydeP - 1.17.1.9 ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001,ko01000 - - - Molybdopterin,Molydop_binding k141_28573_1 218284.CCDN010000004_gene3132 5.76e-31 109.0 2EK2J@1|root,33DT0@2|Bacteria,1VMKI@1239|Firmicutes,4HS9U@91061|Bacilli,1ZJJ0@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_28573_3 218284.CCDN010000004_gene3130 6.67e-98 287.0 COG1595@1|root,COG1595@2|Bacteria,1VB37@1239|Firmicutes,4HMZ2@91061|Bacilli,1ZCWY@1386|Bacillus 91061|Bacilli K Belongs to the sigma-70 factor family. ECF subfamily sigY - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4,Sigma70_r4_2 k141_28573_4 218284.CCDN010000004_gene3128 9.35e-12 64.7 COG0477@1|root,COG2814@2|Bacteria,1U72T@1239|Firmicutes,4HCHH@91061|Bacilli,1ZCHP@1386|Bacillus 91061|Bacilli EGP COG0477 Permeases of the major facilitator superfamily ykuC - - - - - - - - - - - MFS_1 k141_24977_1 218284.CCDN010000001_gene1785 3.59e-232 652.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,1ZBIW@1386|Bacillus 91061|Bacilli V COG1132 ABC-type multidrug transport system, ATPase and permease components mdlB - - ko:K06147,ko:K18890 ko02010,map02010 M00707 - - ko00000,ko00001,ko00002,ko02000 3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran k141_35697_1 1537994.JQFW01000057_gene433 4.56e-21 93.2 COG2755@1|root,COG2755@2|Bacteria,1RE1B@1224|Proteobacteria,1S42Y@1236|Gammaproteobacteria,46DIJ@72275|Alteromonadaceae 1236|Gammaproteobacteria E GDSL-like Lipase/Acylhydrolase family - - - - - - - - - - - - Lipase_GDSL_2 k141_35697_2 1042377.AFPJ01000004_gene343 3.72e-183 522.0 COG0446@1|root,COG0446@2|Bacteria,1Q0P8@1224|Proteobacteria,1T1NQ@1236|Gammaproteobacteria,464PV@72275|Alteromonadaceae 1236|Gammaproteobacteria S Tryptophan halogenase - - 1.14.19.9 ko:K14266 ko00404,ko01130,map00404,map01130 M00789,M00790 R09570 RC00949 ko00000,ko00001,ko00002,ko01000 - - - Trp_halogenase k141_5981_1 690850.Desaf_2054 4.77e-65 213.0 COG0530@1|root,COG0530@2|Bacteria,1QDUB@1224|Proteobacteria,435JZ@68525|delta/epsilon subdivisions,2WZY9@28221|Deltaproteobacteria,2M8JC@213115|Desulfovibrionales 28221|Deltaproteobacteria P PFAM Sodium calcium exchanger membrane region - - - ko:K07301 - - - - ko00000,ko02000 2.A.19.5 - - Na_Ca_ex k141_4793_1 768066.HELO_1134 1e-38 139.0 COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,1RNB5@1236|Gammaproteobacteria,1XHZR@135619|Oceanospirillales 135619|Oceanospirillales C L-carnitine dehydratase bile acid-inducible protein F - - 2.8.3.19 ko:K18702 - - - - ko00000,ko01000 - - - CoA_transf_3 k141_4793_2 768066.HELO_1133 4.79e-95 285.0 COG0119@1|root,COG0119@2|Bacteria,1MUMX@1224|Proteobacteria,1RMUX@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Hydroxymethylglutaryl-CoA lyase mvaB - 4.1.3.4 ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 M00036,M00088 R01360,R08090 RC00502,RC00503,RC01118,RC01946 ko00000,ko00001,ko00002,ko01000 - - - HMGL-like k141_8365_1 1454004.AW11_02812 9.79e-72 232.0 COG2010@1|root,COG2010@2|Bacteria,1RDNN@1224|Proteobacteria 1224|Proteobacteria C Cytochrome c - - - - - - - - - - - - Cytochrome_C554 k141_16914_1 98439.AJLL01000052_gene3635 1.19e-53 189.0 COG0058@1|root,COG0058@2|Bacteria,1G1HB@1117|Cyanobacteria,1JH4T@1189|Stigonemataceae 1117|Cyanobacteria G Protein of unknown function (DUF3417) glgP - 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 - R02111 - ko00000,ko00001,ko01000 - GT35 - DUF3417,Phosphorylase k141_26533_1 189426.PODO_19505 1.31e-40 147.0 28JE7@1|root,2Z98F@2|Bacteria,1UZ9J@1239|Firmicutes,4HHJH@91061|Bacilli,26SHH@186822|Paenibacillaceae 91061|Bacilli S Domain of unknown function (DUF4179) - - - - - - - - - - - - DUF4179 k141_29920_1 218284.CCDN010000005_gene3345 1.27e-309 849.0 COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,4H9T1@91061|Bacilli,1ZB77@1386|Bacillus 91061|Bacilli M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan murE - 6.3.2.13,6.3.2.7 ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 - R02786,R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M k141_10932_1 1131730.BAVI_02514 1.64e-93 286.0 COG0639@1|root,COG0639@2|Bacteria,1UYWX@1239|Firmicutes,4HEJF@91061|Bacilli,1ZFAS@1386|Bacillus 91061|Bacilli T Calcineurin-like phosphoesterase - - 3.1.3.16 ko:K01090 - - - - ko00000,ko01000 - - - Metallophos k141_15731_1 1384049.CD29_10505 1.17e-05 49.7 COG1559@1|root,COG1559@2|Bacteria,1VZ75@1239|Firmicutes,4HRAC@91061|Bacilli,3IYMC@400634|Lysinibacillus 91061|Bacilli S periplasmic solute-binding protein - - - - - - - - - - - - YceG k141_15731_2 935836.JAEL01000100_gene4226 4.5e-61 193.0 COG0704@1|root,COG0704@2|Bacteria,1URN3@1239|Firmicutes,4HEU9@91061|Bacilli,1ZDDZ@1386|Bacillus 91061|Bacilli P Plays a role in the regulation of phosphate uptake phoU - - ko:K02039 - - - - ko00000 - - - PhoU k141_20389_1 558169.AGAV01000005_gene2081 4.14e-47 161.0 COG2391@1|root,COG2391@2|Bacteria,1TSNG@1239|Firmicutes,4HCH9@91061|Bacilli 91061|Bacilli S Sulphur transport - - - ko:K07112 - - - - ko00000 - - - Sulf_transp k141_20389_2 218284.CCDN010000005_gene3211 2.94e-111 322.0 COG1396@1|root,COG1917@1|root,COG1396@2|Bacteria,COG1917@2|Bacteria,1V5G6@1239|Firmicutes,4HF3D@91061|Bacilli,1ZDMI@1386|Bacillus 91061|Bacilli K Cupin domain puuR1 - - - - - - - - - - - Cupin_2,HTH_3 k141_21679_1 1116375.VEJY3_14115 0.0 1700.0 COG2352@1|root,COG2352@2|Bacteria,1MUD5@1224|Proteobacteria,1RPTP@1236|Gammaproteobacteria,1XUG5@135623|Vibrionales 135623|Vibrionales H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle ppc GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0008964,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0055114,GO:0071704,GO:0072350 4.1.1.31 ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 M00168,M00170,M00171,M00172,M00173,M00346,M00374 R00345 RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPcase k141_21679_2 1116375.VEJY3_14120 2.92e-124 354.0 COG1695@1|root,COG1695@2|Bacteria,1MZYS@1224|Proteobacteria,1S9RS@1236|Gammaproteobacteria,1XV2U@135623|Vibrionales 135623|Vibrionales K transcriptional regulators aphA - - ko:K10917 ko02024,ko05111,map02024,map05111 - - - ko00000,ko00001,ko03000 - - - PadR,Vir_act_alpha_C k141_21679_3 223926.28807773 1.26e-214 592.0 COG0685@1|root,COG0685@2|Bacteria,1MUC9@1224|Proteobacteria,1RMXS@1236|Gammaproteobacteria,1XSQ3@135623|Vibrionales 135623|Vibrionales E reductase metF - 1.5.1.20 ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 M00377 R01224,R07168 RC00081 ko00000,ko00001,ko00002,ko01000 - - - MTHFR k141_21679_4 1116375.VEJY3_14130 0.0 1411.0 COG0460@1|root,COG0527@1|root,COG0460@2|Bacteria,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,1RN1G@1236|Gammaproteobacteria,1XSVP@135623|Vibrionales 135623|Vibrionales E Bifunctional aspartate kinase II homoserine dehydrogenase II metL - 1.1.1.3,2.7.2.4 ko:K12525 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00017,M00018,M00526,M00527 R00480,R01773,R01775 RC00002,RC00043,RC00087 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,Homoserine_dh,NAD_binding_3 k141_21679_5 1116375.VEJY3_14135 1.22e-270 741.0 COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,1RMCV@1236|Gammaproteobacteria,1XSFT@135623|Vibrionales 135623|Vibrionales E COG0626 Cystathionine beta-lyases cystathionine gamma-synthases metB - 2.5.1.48 ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017 R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946 RC00020,RC00056,RC00069,RC00420,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000 - - - Cys_Met_Meta_PP k141_21679_6 1219076.N646_1861 8.17e-71 213.0 COG3060@1|root,COG3060@2|Bacteria,1RH3B@1224|Proteobacteria,1S5ZV@1236|Gammaproteobacteria,1XX9T@135623|Vibrionales 135623|Vibrionales K This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis metJ GO:0000096,GO:0003674,GO:0003700,GO:0006082,GO:0006355,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031326,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0140110,GO:1901564,GO:1901605,GO:1903506,GO:2000112,GO:2001141 - ko:K03764 - - - - ko00000,ko03000 - - - MetJ k141_21679_7 1280001.BAOA01000134_gene2089 6.87e-294 803.0 COG0281@1|root,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,1RN5F@1236|Gammaproteobacteria,1XSB5@135623|Vibrionales 135623|Vibrionales C malic enzyme maeB - 1.1.1.40 ko:K00029 ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200 M00169,M00172 R00216 RC00105 ko00000,ko00001,ko00002,ko01000 - - - Malic_M,malic k141_21679_8 945550.VISI1226_19204 1.38e-104 303.0 COG2193@1|root,COG2193@2|Bacteria,1RCW7@1224|Proteobacteria,1S45S@1236|Gammaproteobacteria,1XUPT@135623|Vibrionales 135623|Vibrionales P Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex bfr - 1.16.3.1 ko:K03594 ko00860,map00860 - R00078 RC02758 ko00000,ko00001,ko01000 - - - Ferritin k141_13376_2 218284.CCDN010000001_gene1093 1.5e-96 283.0 COG0204@1|root,COG0204@2|Bacteria,1U8N2@1239|Firmicutes,4HDQR@91061|Bacilli,1ZE5P@1386|Bacillus 91061|Bacilli I 1-acyl-sn-glycerol-3-phosphate acyltransferase plsC - 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase k141_7410_1 649639.Bcell_2934 2.29e-106 327.0 COG0243@1|root,COG0243@2|Bacteria,1VTS0@1239|Firmicutes,4HAZ4@91061|Bacilli,1ZBMY@1386|Bacillus 91061|Bacilli C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - ko:K00372 ko00910,ko01120,map00910,map01120 M00531 R00798,R01106 RC02812 ko00000,ko00001,ko00002,ko01000 - - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding k141_7410_2 1294265.JCM21738_1871 1.42e-22 94.7 COG2181@1|root,COG2181@2|Bacteria,1V067@1239|Firmicutes,4HCYT@91061|Bacilli,1ZDYD@1386|Bacillus 91061|Bacilli C nitrate reductase activity - - - - - - - - - - - - - k141_8583_1 218284.CCDN010000002_gene2156 1.52e-77 257.0 COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,4HAFP@91061|Bacilli,1ZBJ3@1386|Bacillus 91061|Bacilli V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family swrC - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran k141_9737_1 1265505.ATUG01000002_gene2137 3.65e-70 228.0 COG1012@1|root,COG1012@2|Bacteria,1QUBI@1224|Proteobacteria,42P3A@68525|delta/epsilon subdivisions,2WIJU@28221|Deltaproteobacteria,2MMH7@213118|Desulfobacterales 28221|Deltaproteobacteria C Aldehyde dehydrogenase family - - - ko:K04021 ko00620,ko01100,ko01120,map00620,map01100,map01120 - R00228 RC00004,RC01195 ko00000,ko00001 - - - Aldedh k141_353_1 1121472.AQWN01000002_gene2216 1.3e-18 91.3 COG1948@1|root,COG4880@2|Bacteria,1TQK0@1239|Firmicutes,247VC@186801|Clostridia,25ZZT@186807|Peptococcaceae 186801|Clostridia L Secreted protein with C-terminal beta-propeller domain - - - - - - - - - - - - Beta_propel k141_22853_1 1379858.N508_00351 1.21e-27 113.0 COG3808@1|root,COG3808@2|Bacteria,2GFAJ@200930|Deferribacteres 200930|Deferribacteres C Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane hppA - 3.6.1.1 ko:K15987 ko00190,map00190 - - - ko00000,ko00001,ko01000 3.A.10.1 - - H_PPase k141_22853_2 1297617.JPJD01000036_gene780 1.77e-19 85.5 COG0193@1|root,COG0193@2|Bacteria,1V3NB@1239|Firmicutes,24HMC@186801|Clostridia,2686B@186813|unclassified Clostridiales 186801|Clostridia J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis pth - 3.1.1.29 ko:K01056 - - - - ko00000,ko01000,ko03012 - - - Pept_tRNA_hydro k141_12209_1 1453501.JELR01000002_gene300 6.38e-74 231.0 COG0042@1|root,COG0042@2|Bacteria,1MUY1@1224|Proteobacteria,1RN28@1236|Gammaproteobacteria,464FI@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs dusA GO:0002943,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016491,GO:0016627,GO:0017150,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055114,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 - ko:K05539 - - - - ko00000,ko01000,ko03016 - - - Dus k141_10933_1 218284.CCDN010000002_gene2803 3.09e-39 141.0 COG1114@1|root,COG1114@2|Bacteria,1TQIS@1239|Firmicutes,4HAKA@91061|Bacilli,1ZAST@1386|Bacillus 91061|Bacilli E Component of the transport system for branched-chain amino acids brnQ - - ko:K03311 - - - - ko00000 2.A.26 - - Branch_AA_trans k141_15732_1 218284.CCDN010000005_gene3422 2.45e-34 123.0 COG1655@1|root,COG1655@2|Bacteria,1UY0V@1239|Firmicutes,4HDH4@91061|Bacilli,1ZD58@1386|Bacillus 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2225) - - - ko:K09766 - - - - ko00000 - - - DUF2225 k141_27538_1 82654.Pse7367_1527 1.63e-71 238.0 COG0591@1|root,COG0591@2|Bacteria,1G1JV@1117|Cyanobacteria,1H88V@1150|Oscillatoriales 1117|Cyanobacteria E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family putP - - - - - - - - - - - SSF k141_19248_1 1453501.JELR01000002_gene243 1.74e-101 321.0 COG3188@1|root,COG3188@2|Bacteria,1PTRC@1224|Proteobacteria,1S047@1236|Gammaproteobacteria 1236|Gammaproteobacteria NU E-set like domain cblC - - - - - - - - - - - CooC_C,TcfC,Usher_TcfC k141_28850_2 218284.CCDN010000010_gene4390 3.11e-30 112.0 COG1211@1|root,COG1211@2|Bacteria,1V3M7@1239|Firmicutes,4HH2N@91061|Bacilli,1ZCWR@1386|Bacillus 91061|Bacilli I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) ispD GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05633 RC00002 ko00000,ko00001,ko00002,ko01000 - - - IspD k141_22855_1 218284.CCDN010000001_gene797 3.41e-49 167.0 COG1208@1|root,COG1208@2|Bacteria,1VDBC@1239|Firmicutes,4IS8X@91061|Bacilli,1ZDK6@1386|Bacillus 91061|Bacilli GJM Nucleotidyl transferase - - 2.7.7.13,5.4.2.8 ko:K00966,ko:K16881 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 M00114,M00361,M00362 R00885,R01818 RC00002,RC00408 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transferase,PGM_PMM_I k141_12210_1 1294265.JCM21738_2801 2.31e-130 374.0 COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HA2G@91061|Bacilli,1ZAY1@1386|Bacillus 91061|Bacilli IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II lcfA - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding,AMP-binding_C k141_32261_1 59689.fgenesh1_pm.C_scaffold_5001725 4.92e-31 126.0 COG3320@1|root,KOG1221@2759|Eukaryota,37IRY@33090|Viridiplantae,3G9S1@35493|Streptophyta,3HY82@3699|Brassicales 35493|Streptophyta I Catalyzes the reduction of fatty acyl-CoA to fatty alcohols - - 1.2.1.84 ko:K13356 ko00073,ko04146,ko04212,map00073,map04146,map04212 - R09470 RC00004 ko00000,ko00001,ko01000 - - - NAD_binding_4,Sterile k141_16918_1 272630.MexAM1_META1p0685 9.23e-67 225.0 COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,2TQVK@28211|Alphaproteobacteria,1JT8T@119045|Methylobacteriaceae 28211|Alphaproteobacteria C aldehyde oxidase and xanthine dehydrogenase molybdopterin binding iorB - 1.3.99.16 ko:K07303 - - - - ko00000,ko01000 - - - Ald_Xan_dh_C2 k141_4977_1 218284.CCDN010000001_gene1107 4.37e-119 342.0 COG0302@1|root,COG0302@2|Bacteria,1TRNM@1239|Firmicutes,4HAXS@91061|Bacilli,1ZAZD@1386|Bacillus 91061|Bacilli H GTP cyclohydrolase folE GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 ko:K01495 ko00790,ko01100,map00790,map01100 M00126,M00841,M00842,M00843 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 - - - GTP_cyclohydroI k141_12246_2 218284.CCDN010000001_gene298 1.03e-207 575.0 COG0506@1|root,COG0506@2|Bacteria,1TQV3@1239|Firmicutes,4HAC1@91061|Bacilli,1ZB5G@1386|Bacillus 91061|Bacilli E Proline dehydrogenase ycgM GO:0000166,GO:0003674,GO:0003824,GO:0004657,GO:0005488,GO:0006082,GO:0006520,GO:0006560,GO:0006562,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016491,GO:0016645,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 - ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 - R10507 RC00083 ko00000,ko00001,ko01000 - - - Pro_dh k141_5010_1 1294265.JCM21738_2582 2.2e-140 417.0 COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HACY@91061|Bacilli,1ZB8K@1386|Bacillus 91061|Bacilli O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE clpB GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564 - ko:K03695 ko04213,map04213 - - - ko00000,ko00001,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N k141_33537_1 1121441.AUCX01000020_gene668 4.29e-22 101.0 COG0110@1|root,COG3562@1|root,COG0110@2|Bacteria,COG3562@2|Bacteria,1N6SQ@1224|Proteobacteria,42VI7@68525|delta/epsilon subdivisions,2WR74@28221|Deltaproteobacteria,2MAVN@213115|Desulfovibrionales 28221|Deltaproteobacteria Q transferase hexapeptide repeat - - 2.3.1.18 ko:K00633,ko:K03818 - - - - ko00000,ko01000 - - - Hexapep,Hexapep_2 k141_21698_1 1116375.VEJY3_07220 1.38e-95 282.0 COG3381@1|root,COG3381@2|Bacteria,1MWWM@1224|Proteobacteria,1S449@1236|Gammaproteobacteria,1XVDD@135623|Vibrionales 135623|Vibrionales S component of anaerobic dehydrogenases - - - - - - - - - - - - Nitrate_red_del k141_1423_1 218284.CCDN010000001_gene1367 6.46e-183 511.0 COG2996@1|root,COG2996@2|Bacteria,1TQ1Z@1239|Firmicutes,4HDAZ@91061|Bacilli,1ZASM@1386|Bacillus 91061|Bacilli S protein conserved in bacteria yitL - - ko:K00243 - - - - ko00000 - - - S1_2 k141_10959_1 1042377.AFPJ01000020_gene2074 2.6e-140 418.0 COG0308@1|root,COG0308@2|Bacteria,1MUV3@1224|Proteobacteria,1RS0E@1236|Gammaproteobacteria,4666I@72275|Alteromonadaceae 1236|Gammaproteobacteria E Peptidase family M1 domain - - - - - - - - - - - - Peptidase_M1 k141_26581_1 218284.CCDN010000002_gene2229 4.1e-117 357.0 COG5000@1|root,COG5002@1|root,COG5000@2|Bacteria,COG5002@2|Bacteria,1VS6X@1239|Firmicutes,4HV7W@91061|Bacilli,1ZS6R@1386|Bacillus 91061|Bacilli T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,dCache_1 k141_12247_1 1158602.I590_00669 1.27e-22 97.1 COG3935@1|root,COG3935@2|Bacteria,1V69W@1239|Firmicutes,4HJM0@91061|Bacilli,4B2M2@81852|Enterococcaceae 91061|Bacilli L Replication initiation and membrane attachment - - - - - - - - - - - - DnaB_2,Phg_2220_C k141_37063_1 218284.CCDN010000001_gene1123 8.03e-94 275.0 2CSPZ@1|root,32SRK@2|Bacteria,1VBS0@1239|Firmicutes,4HKXQ@91061|Bacilli,1ZI4R@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2487) ypiF - - - - - - - - - - - DUF2487 k141_20415_2 218284.CCDN010000001_gene941 7.72e-165 471.0 COG0403@1|root,COG0403@2|Bacteria,1TQGG@1239|Firmicutes,4HA7P@91061|Bacilli,1ZB0H@1386|Bacillus 91061|Bacilli E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor gcvPA - 1.4.4.2 ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 - R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko01000 - - - GDC-P k141_33538_1 1123242.JH636436_gene590 1.66e-28 119.0 COG0515@1|root,COG0515@2|Bacteria,2IXXT@203682|Planctomycetes 203682|Planctomycetes KLT Serine threonine protein kinase - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - Pkinase k141_3897_1 1196031.ALEG01000006_gene508 9.54e-71 227.0 COG1488@1|root,COG1488@2|Bacteria,1TPDW@1239|Firmicutes,4HAI4@91061|Bacilli,1ZCGY@1386|Bacillus 91061|Bacilli H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP pncB - 6.3.4.21 ko:K00763 ko00760,ko01100,map00760,map01100 - R01724 RC00033 ko00000,ko00001,ko01000 - - iYO844.BSU31750 NAPRTase k141_13407_2 223926.28809955 1.65e-56 196.0 COG3144@1|root,COG3144@2|Bacteria,1N86W@1224|Proteobacteria,1SER0@1236|Gammaproteobacteria,1XXIJ@135623|Vibrionales 135623|Vibrionales N Flagellar hook-length control protein FliK - - - ko:K02414 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_hook k141_13407_3 674977.VMC_26140 7.32e-59 187.0 COG1580@1|root,COG1580@2|Bacteria,1NC4D@1224|Proteobacteria,1SE3R@1236|Gammaproteobacteria,1XX7B@135623|Vibrionales 135623|Vibrionales N Controls the rotational direction of flagella during chemotaxis lafL - - ko:K02415 - - - - ko00000,ko02035 - - - FliL k141_13407_4 675814.VIC_004744 1.7e-138 395.0 COG1191@1|root,COG1191@2|Bacteria,1RCX0@1224|Proteobacteria,1S4UA@1236|Gammaproteobacteria,1XV95@135623|Vibrionales 135623|Vibrionales K Belongs to the sigma-70 factor family lafS - - ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 - - - ko00000,ko00001,ko02035,ko03021 - - - Sigma70_r2,Sigma70_r3,Sigma70_r4 k141_13407_5 945543.VIBR0546_10824 2.82e-179 502.0 COG1291@1|root,COG1291@2|Bacteria,1MXK3@1224|Proteobacteria,1RNTF@1236|Gammaproteobacteria,1XSAJ@135623|Vibrionales 135623|Vibrionales N flagellar motor motA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - MotA_ExbB k141_13407_6 1219065.VPR01S_03_01460 2.29e-178 503.0 COG1360@1|root,COG1360@2|Bacteria,1MW1Y@1224|Proteobacteria,1RPQ9@1236|Gammaproteobacteria,1XV9X@135623|Vibrionales 135623|Vibrionales N Membrane MotB of proton-channel complex MotA/MotB - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02557 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - MotB_plug,OmpA k141_13407_7 945543.VIBR0546_10834 9.7e-42 139.0 2CHPC@1|root,33C3I@2|Bacteria,1NGVQ@1224|Proteobacteria,1SHND@1236|Gammaproteobacteria,1XYN2@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_13407_8 223926.28809662 2.15e-50 164.0 COG3266@1|root,COG3266@2|Bacteria,1QK5V@1224|Proteobacteria,1TI92@1236|Gammaproteobacteria,1XYP2@135623|Vibrionales 135623|Vibrionales S Sporulation related domain - - - - - - - - - - - - SPOR k141_13407_9 1129374.AJE_05411 7.92e-40 139.0 COG0454@1|root,COG0456@2|Bacteria,1N538@1224|Proteobacteria,1S8WA@1236|Gammaproteobacteria,468RH@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_7 k141_19285_1 218284.CCDN010000004_gene3126 9.21e-135 394.0 COG1288@1|root,COG1288@2|Bacteria,1TQJ0@1239|Firmicutes,4H9P7@91061|Bacilli,1ZBC6@1386|Bacillus 91061|Bacilli S Membrane ycgA - - - - - - - - - - - DcuC k141_5012_1 1042377.AFPJ01000019_gene2533 2.3e-86 268.0 COG4242@1|root,COG4242@2|Bacteria,1PR9J@1224|Proteobacteria,1RVJH@1236|Gammaproteobacteria,469D6@72275|Alteromonadaceae 1236|Gammaproteobacteria PQ Peptidase family S51 cphB - 3.4.15.6 ko:K13282 - - R09722 RC00064,RC00141 ko00000,ko01000,ko01002 - - - Peptidase_S51 k141_32283_1 1279017.AQYJ01000025_gene733 1.91e-129 400.0 COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,1RNCU@1236|Gammaproteobacteria,464IX@72275|Alteromonadaceae 1236|Gammaproteobacteria L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd GO:0000715,GO:0000716,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006283,GO:0006289,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008094,GO:0008150,GO:0008152,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0015616,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031326,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0043175,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051276,GO:0051716,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF k141_18175_1 1307436.PBF_01055 1.82e-21 91.3 COG1366@1|root,COG1366@2|Bacteria,1TT64@1239|Firmicutes,4HCAK@91061|Bacilli,1ZDJS@1386|Bacillus 91061|Bacilli T STAS domain rsbRD - - ko:K17763 - - - - ko00000,ko03021 - - - HATPase_c,HisKA,STAS k141_382_1 218284.CCDN010000006_gene3665 2.6e-101 305.0 COG1301@1|root,COG1301@2|Bacteria,1TPME@1239|Firmicutes,4HB4X@91061|Bacilli,1ZDVI@1386|Bacillus 91061|Bacilli C Sodium:dicarboxylate symporter family - - - - - - - - - - - - SDF k141_9768_1 218284.CCDN010000002_gene2045 1.55e-98 303.0 28HMX@1|root,2Z7WB@2|Bacteria,1TPJG@1239|Firmicutes,4HBRI@91061|Bacilli,1ZCDH@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_12248_1 1279017.AQYJ01000029_gene3344 8.85e-61 196.0 COG1092@1|root,COG1092@2|Bacteria,1PUHQ@1224|Proteobacteria,1RN8N@1236|Gammaproteobacteria,466G3@72275|Alteromonadaceae 1236|Gammaproteobacteria J S-adenosylmethionine-dependent methyltransferase - - 2.1.1.191 ko:K06969 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_SAM k141_5013_1 935837.JAEK01000004_gene4776 1.86e-96 289.0 COG1968@1|root,COG1968@2|Bacteria,1TPFA@1239|Firmicutes,4HB0M@91061|Bacilli,1ZD80@1386|Bacillus 91061|Bacilli V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin uppP - 3.6.1.27 ko:K06153 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - BacA k141_25257_1 1116375.VEJY3_17036 7.29e-149 423.0 COG0583@1|root,COG0583@2|Bacteria,1R509@1224|Proteobacteria,1RSBX@1236|Gammaproteobacteria,1XVV1@135623|Vibrionales 135623|Vibrionales K Bacterial regulatory helix-turn-helix protein, lysR family - - - ko:K03566 ko02026,map02026 - - - ko00000,ko00001,ko03000 - - - HTH_1,LysR_substrate k141_25257_2 1116375.VEJY3_17041 5.89e-238 657.0 COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,1RP4T@1236|Gammaproteobacteria,1XV8C@135623|Vibrionales 135623|Vibrionales E COG0079 Histidinol-phosphate aromatic aminotransferase and cobyric acid decarboxylase - - 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k141_25257_3 1116375.VEJY3_17046 2.47e-175 489.0 COG0834@1|root,COG0834@2|Bacteria,1NT2J@1224|Proteobacteria,1S09P@1236|Gammaproteobacteria,1Y249@135623|Vibrionales 135623|Vibrionales ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain - - - ko:K02030,ko:K10022 ko02010,map02010 M00235,M00236 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.11 - - SBP_bac_3 k141_25257_4 1116375.VEJY3_17051 3.21e-68 208.0 2EF37@1|root,338WA@2|Bacteria,1P2WM@1224|Proteobacteria,1SRQX@1236|Gammaproteobacteria,1XXSX@135623|Vibrionales 135623|Vibrionales S Ribosome recycling factor - - - - - - - - - - - - RRF_GI k141_2682_2 218284.CCDN010000008_gene4205 3.03e-86 258.0 COG1986@1|root,COG1986@2|Bacteria,1V6CG@1239|Firmicutes,4HIVY@91061|Bacilli,1ZGKX@1386|Bacillus 91061|Bacilli F Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions yjjX GO:0003674,GO:0003824,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111 - - - - - - - - - - NTPase_I-T k141_20416_1 1279017.AQYJ01000027_gene1669 2.62e-131 390.0 COG0515@1|root,COG0631@1|root,COG0515@2|Bacteria,COG0631@2|Bacteria,1MV1P@1224|Proteobacteria,1RNQN@1236|Gammaproteobacteria,464NH@72275|Alteromonadaceae 1236|Gammaproteobacteria T Serine threonine protein - - 3.1.3.16 ko:K01090 - - - - ko00000,ko01000 - - - PP2C_2,Pkinase k141_15753_1 223926.28807633 4.85e-98 291.0 COG2066@1|root,COG2066@2|Bacteria,1MWB5@1224|Proteobacteria,1RMY9@1236|Gammaproteobacteria,1XUUJ@135623|Vibrionales 135623|Vibrionales E Belongs to the glutaminase family glsA GO:0003674,GO:0003824,GO:0004359,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006543,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009064,GO:0009065,GO:0009084,GO:0009987,GO:0016053,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 3.5.1.2 ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 - R00256,R01579 RC00010,RC02798 ko00000,ko00001,ko01000 - - - Glutaminase k141_15753_2 223926.28807632 4.89e-273 747.0 COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,1RN6I@1236|Gammaproteobacteria,1XTWK@135623|Vibrionales 135623|Vibrionales H Involved in the biosynthesis of porphyrin-containing compound yggW - - - - - - - - - - - HemN_C,Radical_SAM k141_22903_1 218284.CCDN010000002_gene2165 3.87e-144 424.0 COG0025@1|root,COG0025@2|Bacteria,1U8X3@1239|Firmicutes,4HBQR@91061|Bacilli,1ZQCD@1386|Bacillus 91061|Bacilli P Sodium/hydrogen exchanger family - - - - - - - - - - - - Na_H_Exchanger,TrkA_N k141_37065_1 218284.CCDN010000001_gene1346 4.32e-52 174.0 COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,4HF1R@91061|Bacilli,1ZDU3@1386|Bacillus 91061|Bacilli M Belongs to the peptidase S11 family - - 3.4.16.4 ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - PBP5_C,Peptidase_S11 k141_35892_1 1116375.VEJY3_14285 6.36e-135 390.0 COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,1RMV1@1236|Gammaproteobacteria,1XSTJ@135623|Vibrionales 135623|Vibrionales E acetylornithine aminotransferase argD GO:0003674,GO:0003824,GO:0003992,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.11,2.6.1.17 ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R02283,R04475 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 k141_35892_2 1116375.VEJY3_14280 1.08e-242 667.0 COG3138@1|root,COG3138@2|Bacteria,1MWHC@1224|Proteobacteria,1RMXG@1236|Gammaproteobacteria,1XSR5@135623|Vibrionales 135623|Vibrionales H COG3138 Arginine ornithine N-succinyltransferase beta subunit astA - 2.3.1.109 ko:K00673 ko00330,ko01100,map00330,map01100 - R00832 RC00004,RC00064 ko00000,ko00001,ko01000 - - - AstA k141_35892_3 1116375.VEJY3_14275 9.61e-118 348.0 COG1012@1|root,COG1012@2|Bacteria,1MV2I@1224|Proteobacteria,1RPQW@1236|Gammaproteobacteria,1XTD0@135623|Vibrionales 135623|Vibrionales C Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate astD GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.2.1.71 ko:K06447 ko00330,ko01100,map00330,map01100 - R05049 RC00080 ko00000,ko00001,ko01000 - - - Aldedh k141_8608_1 42565.FP66_09990 8.98e-29 111.0 COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,1RM7Q@1236|Gammaproteobacteria,1XHU3@135619|Oceanospirillales 135619|Oceanospirillales J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA prfA - - ko:K02835 - - - - ko00000,ko03012 - - - PCRF,RF-1 k141_8608_2 42565.FP66_09985 1.93e-63 205.0 COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,1RNQ8@1236|Gammaproteobacteria,1XHBS@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) hemA - 1.2.1.70 ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R04109 RC00055,RC00149 ko00000,ko00001,ko00002,ko01000 - - - GlutR_N,GlutR_dimer,Shikimate_DH k141_31225_2 218284.CCDN010000007_gene3853 1.2e-40 140.0 COG1136@1|root,COG1136@2|Bacteria,1TNZG@1239|Firmicutes,4H9UT@91061|Bacilli,1ZCDW@1386|Bacillus 91061|Bacilli V ABC transporter, ATP-binding protein bceA - - ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 M00258,M00314,M00730,M00732,M00737,M00738 - - ko00000,ko00001,ko00002,ko01504,ko02000 3.A.1,3.A.1.134.3,3.A.1.134.7 - - ABC_tran k141_34760_1 866895.HBHAL_4670 1.96e-77 239.0 COG3001@1|root,COG3001@2|Bacteria,1U79A@1239|Firmicutes,4HAZS@91061|Bacilli,3NEM4@45667|Halobacillus 91061|Bacilli G Fructosamine kinase - - - - - - - - - - - - Fructosamin_kin k141_32284_2 1319815.HMPREF0202_00608 2.69e-06 48.5 COG0721@1|root,COG0721@2|Bacteria,37APP@32066|Fusobacteria 32066|Fusobacteria J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatC - 6.3.5.6,6.3.5.7 ko:K02435 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Glu-tRNAGln k141_26583_2 218284.CCDN010000002_gene2191 2.25e-139 397.0 COG0212@1|root,COG0212@2|Bacteria,1UYS3@1239|Firmicutes,4HBSY@91061|Bacilli,1ZCAA@1386|Bacillus 91061|Bacilli H 5-formyltetrahydrofolate cyclo-ligase family - - 6.3.3.2 ko:K01934 ko00670,ko01100,map00670,map01100 - R02301 RC00183 ko00000,ko00001,ko01000 - - - 5-FTHF_cyc-lig k141_26583_3 218284.CCDN010000002_gene2190 2.15e-85 253.0 2A6RZ@1|root,30VK4@2|Bacteria,1V5GS@1239|Firmicutes,4HHIA@91061|Bacilli,1ZG9Z@1386|Bacillus 91061|Bacilli S Predicted integral membrane protein (DUF2269) - - - - - - - - - - - - DUF2269 k141_16966_1 1042377.AFPJ01000024_gene736 2.12e-49 165.0 COG3945@1|root,COG3945@2|Bacteria 2|Bacteria P hemerythrin HHE cation binding domain VP0501 - - - - - - - - - - - Hemerythrin k141_16966_2 1279017.AQYJ01000028_gene2380 3.3e-136 390.0 COG0664@1|root,COG0664@2|Bacteria,1MVGE@1224|Proteobacteria,1RPTB@1236|Gammaproteobacteria,466GX@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases fnr - - ko:K01420 - - - - ko00000,ko03000 - - - HTH_Crp_2,cNMP_binding k141_26868_1 218284.CCDN010000005_gene3448 1.5e-149 444.0 COG1009@1|root,COG2111@1|root,COG1009@2|Bacteria,COG2111@2|Bacteria,1TQW4@1239|Firmicutes,4H9YR@91061|Bacilli,1ZAZ0@1386|Bacillus 91061|Bacilli CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit mrpA - - ko:K05565 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - DUF4040,Proton_antipo_M,Proton_antipo_N k141_10099_2 1116375.VEJY3_02260 2.36e-116 334.0 COG3945@1|root,COG3945@2|Bacteria,1NDGV@1224|Proteobacteria,1SGA3@1236|Gammaproteobacteria,1XWZS@135623|Vibrionales 135623|Vibrionales S Hemerythrin HHE cation binding domain - - - - - - - - - - - - Hemerythrin k141_10099_3 223926.28805483 1.23e-155 437.0 COG0692@1|root,COG0692@2|Bacteria,1MV80@1224|Proteobacteria,1RPDH@1236|Gammaproteobacteria,1XU4K@135623|Vibrionales 135623|Vibrionales L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine ung GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360 3.2.2.27 ko:K03648 ko03410,ko05340,map03410,map05340 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG k141_10099_4 1116375.VEJY3_02250 7.54e-211 582.0 COG0648@1|root,COG0648@2|Bacteria,1MX4Y@1224|Proteobacteria,1RQ60@1236|Gammaproteobacteria,1XSWK@135623|Vibrionales 135623|Vibrionales L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin nfo GO:0003674,GO:0003824,GO:0003906,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0008833,GO:0009987,GO:0016787,GO:0016788,GO:0016888,GO:0016893,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.21.2 ko:K01151 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - AP_endonuc_2 k141_641_2 1231190.NA8A_05853 5.37e-46 166.0 COG0438@1|root,COG0438@2|Bacteria,1N01H@1224|Proteobacteria,2UNWG@28211|Alphaproteobacteria,43I22@69277|Phyllobacteriaceae 28211|Alphaproteobacteria M Glycosyl transferases group 1 - - - - - - - - - - - - Glycos_transf_1 k141_641_3 266117.Rxyl_0563 1.73e-43 156.0 COG0463@1|root,COG0463@2|Bacteria,2HNJK@201174|Actinobacteria,4CPKZ@84995|Rubrobacteria 84995|Rubrobacteria M Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2,TPR_16 k141_641_4 675814.VIC_001377 1.03e-252 697.0 COG1192@1|root,COG1192@2|Bacteria,1MVJU@1224|Proteobacteria,1THFQ@1236|Gammaproteobacteria,1XVFV@135623|Vibrionales 135623|Vibrionales D AAA domain - - - - - - - - - - - - AAA_31 k141_641_5 675813.VIB_000105 3.18e-147 427.0 COG1475@1|root,COG1475@2|Bacteria,1MWF4@1224|Proteobacteria,1RPM9@1236|Gammaproteobacteria,1XW08@135623|Vibrionales 135623|Vibrionales K ParB family - - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParB k141_20667_2 1444310.JANV01000162_gene1198 4.45e-15 81.3 2DC6Z@1|root,2ZD43@2|Bacteria 2|Bacteria S HNH endonuclease - - - - - - - - - - - - HNH_3 k141_20667_3 1121121.KB894317_gene4211 5.74e-18 77.0 COG3311@1|root,COG3311@2|Bacteria,1VKNA@1239|Firmicutes,4HRVB@91061|Bacilli 91061|Bacilli K Helix-turn-helix domain - - - - - - - - - - - - HTH_17 k141_4129_1 1116375.VEJY3_18161 6.57e-115 343.0 COG1638@1|root,COG1638@2|Bacteria,1MVHI@1224|Proteobacteria,1RP9D@1236|Gammaproteobacteria,1XUMG@135623|Vibrionales 135623|Vibrionales G Bacterial extracellular solute-binding protein, family 7 - - - - - - - - - - - - DctP k141_5320_1 653045.Strvi_3806 6.72e-37 134.0 COG2197@1|root,COG2197@2|Bacteria,2GJRY@201174|Actinobacteria 201174|Actinobacteria T response regulator - - - - - - - - - - - - GerE,Response_reg k141_27690_1 574375.BAGA_25075 5.02e-43 143.0 COG0346@1|root,COG0346@2|Bacteria,1V6XU@1239|Firmicutes,4HIFI@91061|Bacilli,1ZHFW@1386|Bacillus 91061|Bacilli E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily ywkD - - ko:K08234 - - - - ko00000 - - - Glyoxalase k141_27690_2 1294265.JCM21738_1050 8.12e-54 170.0 COG2172@1|root,COG2172@2|Bacteria,1V6Y4@1239|Firmicutes,4HIQU@91061|Bacilli,1ZG7T@1386|Bacillus 91061|Bacilli T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase) rsbT - 2.7.11.1 ko:K17752 - - - - ko00000,ko01000,ko01001,ko03021 - - - HATPase_c,HATPase_c_2 k141_24220_1 218284.CCDN010000001_gene176 1.43e-146 434.0 COG0318@1|root,COG0318@2|Bacteria,1V2NE@1239|Firmicutes,4HBPA@91061|Bacilli,1ZDIG@1386|Bacillus 91061|Bacilli IQ PFAM AMP-dependent synthetase and ligase - - - - - - - - - - - - - k141_12574_1 218284.CCDN010000002_gene2310 2.94e-160 464.0 COG1073@1|root,COG1073@2|Bacteria,1UQS2@1239|Firmicutes,4HAMM@91061|Bacilli,1ZF40@1386|Bacillus 91061|Bacilli S X-Pro dipeptidyl-peptidase (S15 family) - - - - - - - - - - - - Hydrolase_4,Peptidase_S15 k141_13715_1 1380358.JADJ01000003_gene4583 4.78e-29 107.0 2C3KM@1|root,32UH0@2|Bacteria,1N3F2@1224|Proteobacteria,1S9U2@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_13715_2 1453501.JELR01000001_gene2692 0.0 1401.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,4648N@72275|Alteromonadaceae 1236|Gammaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K18138 ko01501,ko01503,map01501,map01503 M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2 - - ACR_tran k141_10100_1 1385517.N800_09895 7.21e-50 165.0 COG0845@1|root,COG0845@2|Bacteria,1MUG6@1224|Proteobacteria,1RP16@1236|Gammaproteobacteria,1X4UP@135614|Xanthomonadales 135614|Xanthomonadales M secretion protein - - - ko:K01993 - - - - ko00000 - - - Biotin_lipoyl_2,HlyD_3 k141_30101_1 1294265.JCM21738_4007 5.43e-120 351.0 COG0439@1|root,COG0439@2|Bacteria,1TP16@1239|Firmicutes,4HA40@91061|Bacilli,1ZBTG@1386|Bacillus 91061|Bacilli I Biotin carboxylase accC2 - 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 k141_6492_1 218284.CCDN010000001_gene1023 1.03e-121 352.0 COG3570@1|root,COG3570@2|Bacteria,1V5G9@1239|Firmicutes,4HH9E@91061|Bacilli,1ZFTN@1386|Bacillus 91061|Bacilli V Aminoglycoside/hydroxyurea antibiotic resistance kinase - - 2.7.1.72 ko:K04343 - M00766 R02225 RC00002,RC00078 br01600,ko00000,ko00002,ko01000,ko01504 - - - APH_6_hur k141_31358_2 218284.CCDN010000007_gene3948 9.57e-208 574.0 COG0010@1|root,COG0010@2|Bacteria,1TP2A@1239|Firmicutes,4HA7S@91061|Bacilli,1ZB9A@1386|Bacillus 91061|Bacilli E Belongs to the arginase family speB - 3.5.3.11 ko:K01480 ko00330,ko01100,map00330,map01100 M00133 R01157 RC00024,RC00329 ko00000,ko00001,ko00002,ko01000 - - - Arginase k141_8890_1 1116375.VEJY3_20531 4.54e-42 147.0 2AFXB@1|root,3160U@2|Bacteria,1RI5S@1224|Proteobacteria,1S87Z@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_8890_2 1116375.VEJY3_20526 2.85e-169 481.0 COG0496@1|root,COG0496@2|Bacteria,1R65V@1224|Proteobacteria,1T0BU@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Acid phosphatase - - 3.1.3.5 ko:K03787 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - SurE k141_8890_4 1120970.AUBZ01000038_gene648 8.36e-08 58.2 COG4968@1|root,COG4968@2|Bacteria,1R4X4@1224|Proteobacteria,1T22U@1236|Gammaproteobacteria 1236|Gammaproteobacteria NU Prokaryotic N-terminal methylation motif - - - ko:K10925 ko05111,map05111 - - - ko00000,ko00001,ko02044 - - - N_methyl k141_642_1 1174504.AJTN02000003_gene2076 2.11e-52 182.0 COG2304@1|root,COG2304@2|Bacteria,1UZKX@1239|Firmicutes,4HCSC@91061|Bacilli,1ZBWZ@1386|Bacillus 91061|Bacilli S protein containing a von Willebrand factor type A (vWA) domain - - - - - - - - - - - - VWA k141_18418_1 1279017.AQYJ01000029_gene3393 3.57e-49 172.0 COG3182@1|root,COG3182@2|Bacteria,1MVET@1224|Proteobacteria,1RY6J@1236|Gammaproteobacteria,465II@72275|Alteromonadaceae 1236|Gammaproteobacteria S PepSY-associated TM region - - - - - - - - - - - - PepSY_TM k141_18418_2 1279017.AQYJ01000029_gene3394 4.06e-68 210.0 COG2153@1|root,COG2153@2|Bacteria,1MZHA@1224|Proteobacteria,1S9IF@1236|Gammaproteobacteria,467VR@72275|Alteromonadaceae 1236|Gammaproteobacteria S Acetyltransferase (GNAT) domain elaA - - ko:K02348 - - - - ko00000 - - - Acetyltransf_10 k141_18418_3 1173026.Glo7428_1546 2.38e-09 58.2 COG0668@1|root,COG0668@2|Bacteria,1G1BH@1117|Cyanobacteria 1117|Cyanobacteria M PFAM Mechanosensitive ion channel - - - - - - - - - - - - MS_channel,TM_helix k141_10101_1 218284.CCDN010000004_gene3118 6.27e-59 186.0 COG0394@1|root,COG0394@2|Bacteria,1U8S1@1239|Firmicutes,4IIQ8@91061|Bacilli,1ZNXR@1386|Bacillus 91061|Bacilli T Low molecular weight phosphatase family - - - - - - - - - - - - - k141_36060_1 1231057.AMGD01000021_gene3162 1.4e-69 220.0 COG0226@1|root,COG0226@2|Bacteria,1TQ5X@1239|Firmicutes,4HBEB@91061|Bacilli,26EMA@186818|Planococcaceae 91061|Bacilli P COG0226 ABC-type phosphate transport system, periplasmic component pstS GO:0003674,GO:0005488,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015698,GO:0042301,GO:0043167,GO:0043168,GO:0051179,GO:0051234 - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - PBP_like_2 k141_23194_1 10724.PORTL_BPSPP 5.62e-96 303.0 4QAR7@10239|Viruses,4QUW5@35237|dsDNA viruses no RNA stage,4QPKJ@28883|Caudovirales,4QKQ3@10699|Siphoviridae 10699|Siphoviridae S Phage portal protein, SPP1 Gp6-like - GO:0005575,GO:0019012,GO:0019028,GO:0032991,GO:0044423,GO:0046729,GO:0046798 - - - - - - - - - - - k141_23194_2 1445809.A0A0A7AQU4_9CAUD 4.96e-224 626.0 4QARF@10239|Viruses,4QZ65@35237|dsDNA viruses no RNA stage,4QSYZ@28883|Caudovirales,4QM3S@10699|Siphoviridae 10699|Siphoviridae S Phage terminase large subunit - - - - - - - - - - - - - k141_23194_3 742740.HMPREF9474_02359 1.22e-13 69.3 COG2963@1|root,COG2963@2|Bacteria,1V6XW@1239|Firmicutes,24K7P@186801|Clostridia,220EF@1506553|Lachnoclostridium 186801|Clostridia L transposase activity - - - - - - - - - - - - HTH_23,HTH_Tnp_1 k141_17119_1 1294265.JCM21738_4261 1.72e-103 322.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,4HAN8@91061|Bacilli,1ZBRJ@1386|Bacillus 91061|Bacilli C belongs to the iron- containing alcohol dehydrogenase family adh - 1.1.1.1,1.2.1.10 ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 - R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 ko00000,ko00001,ko01000 - - - Aldedh,Fe-ADH k141_1619_1 218284.CCDN010000006_gene3757 1.6e-204 575.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,4HCDP@91061|Bacilli,1ZD3N@1386|Bacillus 91061|Bacilli E Glutamate/Leucine/Phenylalanine/Valine dehydrogenase gdhA - 1.4.1.3 ko:K00261 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 M00740 R00243,R00248 RC00006,RC02799 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ELFV_dehydrog,ELFV_dehydrog_N k141_24222_1 218284.CCDN010000008_gene4198 1.51e-94 298.0 COG1523@1|root,COG1523@2|Bacteria,1TP3M@1239|Firmicutes,4HBP5@91061|Bacilli,1ZC85@1386|Bacillus 91061|Bacilli G Belongs to the glycosyl hydrolase 13 family amyX - 3.2.1.41 ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 - R02111 - ko00000,ko00001,ko01000 - CBM48,GH13 - Alpha-amylase,CBM_48 k141_32465_1 218284.CCDN010000007_gene3921 8.07e-79 241.0 COG1028@1|root,COG1028@2|Bacteria,1TVGW@1239|Firmicutes,4HAP9@91061|Bacilli,1ZQ6A@1386|Bacillus 91061|Bacilli IQ Enoyl-(Acyl carrier protein) reductase - - - - - - - - - - - - adh_short k141_25542_1 1042377.AFPJ01000028_gene2303 7.77e-110 321.0 COG0451@1|root,COG0451@2|Bacteria,1MWVJ@1224|Proteobacteria,1RNDT@1236|Gammaproteobacteria,4673H@72275|Alteromonadaceae 1236|Gammaproteobacteria GM COG0451 Nucleoside-diphosphate-sugar epimerases - - - - - - - - - - - - Epimerase,NAD_binding_10,RmlD_sub_bind k141_26871_1 218284.CCDN010000002_gene2135 1.31e-112 345.0 COG0210@1|root,COG0210@2|Bacteria,1TPVG@1239|Firmicutes,4HBVF@91061|Bacilli,1ZCF6@1386|Bacillus 91061|Bacilli L DNA helicase yjcD - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C,YdjO k141_28995_1 1116375.VEJY3_03485 0.0 1323.0 COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,1XSZD@135623|Vibrionales 135623|Vibrionales P COG2217 Cation transport ATPase copA GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0051179,GO:0051234 3.6.3.54 ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - - E1-E2_ATPase,HMA,Hydrolase k141_28995_2 1116375.VEJY3_03480 4.06e-105 303.0 COG3019@1|root,COG3019@2|Bacteria,1MZ9V@1224|Proteobacteria,1S9CQ@1236|Gammaproteobacteria,1XX3N@135623|Vibrionales 135623|Vibrionales S Protein of unknown function, DUF copG - - - - - - - - - - - DUF411 k141_28995_3 223926.28805741 0.0 1595.0 COG3525@1|root,COG3525@2|Bacteria,1MVDE@1224|Proteobacteria,1RMNI@1236|Gammaproteobacteria,1XTQZ@135623|Vibrionales 135623|Vibrionales G COG3525 N-acetyl-beta-hexosaminidase chb - 3.2.1.52 ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 M00079 R00022,R06004,R11316 RC00049 ko00000,ko00001,ko00002,ko01000,ko03110 - GH20 - CHB_HEX,CHB_HEX_C,Glyco_hydro_20,Glyco_hydro_20b k141_28995_4 1116375.VEJY3_03465 7.82e-167 472.0 COG3735@1|root,COG3735@2|Bacteria,1MVCW@1224|Proteobacteria,1RRI8@1236|Gammaproteobacteria,1XVUE@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria - - - ko:K09973 - - - - ko00000 - - - TraB k141_18419_1 1444310.JANV01000195_gene2723 2.65e-39 137.0 COG1280@1|root,COG1280@2|Bacteria,1V1RZ@1239|Firmicutes,4IS1Q@91061|Bacilli,1ZS0F@1386|Bacillus 91061|Bacilli E LysE type translocator - - - - - - - - - - - - LysE k141_21896_1 218284.CCDN010000004_gene3091 9.36e-290 800.0 COG1109@1|root,COG1109@2|Bacteria,1TP2N@1239|Firmicutes,4HADU@91061|Bacilli,1ZBEM@1386|Bacillus 91061|Bacilli G Phosphoglucomutase pgcA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 5.4.2.2 ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00549 R00959,R01057,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV k141_25544_1 1231057.AMGD01000010_gene1429 2.51e-100 295.0 COG0378@1|root,COG0378@2|Bacteria,1TS00@1239|Firmicutes,4HC5C@91061|Bacilli,26DS8@186818|Planococcaceae 91061|Bacilli KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG ureG - - ko:K03189,ko:K04652 - - - - ko00000,ko03110 - - - cobW k141_31359_1 1453501.JELR01000002_gene1205 1.05e-112 343.0 COG1404@1|root,COG5640@1|root,COG1404@2|Bacteria,COG5640@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria,464PM@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG1404 Subtilisin-like serine proteases - GO:0005575,GO:0005576 - ko:K14645 ko02024,map02024 - - - ko00000,ko00001,ko01000,ko01002,ko03110 - - - PKD,PPC,P_proprotein,Peptidase_S8 k141_32466_1 1042377.AFPJ01000043_gene902 1.37e-85 266.0 COG1040@1|root,COG1040@2|Bacteria,1REX9@1224|Proteobacteria,1S568@1236|Gammaproteobacteria,4671D@72275|Alteromonadaceae 1236|Gammaproteobacteria S competence protein - - - - - - - - - - - - - k141_10102_1 1123487.KB892857_gene2435 4.32e-06 53.9 COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2VI4Q@28216|Betaproteobacteria,2KVHE@206389|Rhodocyclales 206389|Rhodocyclales O Belongs to the peptidase S1C family - - 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ,PDZ_2,Trypsin_2 k141_10102_2 640081.Dsui_0048 4.69e-50 170.0 COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,2VGZK@28216|Betaproteobacteria,2KUQQ@206389|Rhodocyclales 206389|Rhodocyclales F Belongs to the SAICAR synthetase family purC - 6.3.2.6 ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04591 RC00064,RC00162 ko00000,ko00001,ko00002,ko01000 - - - SAICAR_synt k141_18420_1 218284.CCDN010000005_gene3257 1.28e-109 322.0 COG1307@1|root,COG1307@2|Bacteria,1TQDI@1239|Firmicutes,4HAYQ@91061|Bacilli,1ZCK2@1386|Bacillus 91061|Bacilli S protein conserved in bacteria yitS - - - - - - - - - - - DegV k141_27692_1 365044.Pnap_2179 1.43e-36 133.0 COG3212@1|root,COG3212@2|Bacteria,1N0D3@1224|Proteobacteria 1224|Proteobacteria Q calcium- and calmodulin-responsive adenylate cyclase activity - - - - - - - - - - - - PepSY k141_27692_2 1177181.T9A_01951 0.000115 45.4 COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,1S98A@1236|Gammaproteobacteria,1XKG1@135619|Oceanospirillales 135619|Oceanospirillales O Belongs to the small heat shock protein (HSP20) family - - - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 k141_8892_1 1294265.JCM21738_661 2.27e-55 179.0 COG0755@1|root,COG0755@2|Bacteria,1U8IP@1239|Firmicutes,4HD6H@91061|Bacilli,1ZBFP@1386|Bacillus 91061|Bacilli O cytochrome C hemX GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008152,GO:0015886,GO:0016020,GO:0044464,GO:0051179,GO:0051181,GO:0051234,GO:0055114,GO:0071702,GO:0071705,GO:0071944,GO:1901678 - ko:K02497 - - - - ko00000 - - - Cytochrom_C_asm k141_5322_1 498211.CJA_3824 6.42e-35 120.0 COG0759@1|root,COG0759@2|Bacteria,1N6U4@1224|Proteobacteria,1SCG6@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Could be involved in insertion of integral membrane proteins into the membrane yidD GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0031224,GO:0031226,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150 - ko:K08998 - - - - ko00000 - - - Haemolytic k141_5322_2 1042377.AFPJ01000012_gene1343 1.72e-78 237.0 COG0594@1|root,COG0594@2|Bacteria,1MZQE@1224|Proteobacteria,1S90M@1236|Gammaproteobacteria,468AM@72275|Alteromonadaceae 1236|Gammaproteobacteria J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme rnpA GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031974,GO:0031981,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 ko:K03536 - - - - ko00000,ko01000,ko03016 - - - Ribonuclease_P k141_12575_1 218284.CCDN010000001_gene228 2.07e-231 641.0 COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,4HA7K@91061|Bacilli,1ZDDX@1386|Bacillus 91061|Bacilli F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction ackA - 2.7.2.1 ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00315,R01353 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - Acetate_kinase k141_17121_6 1279017.AQYJ01000027_gene1744 2.49e-123 359.0 COG1108@1|root,COG1108@2|Bacteria,1MVC2@1224|Proteobacteria,1RPYF@1236|Gammaproteobacteria,465VC@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1108 ABC-type Mn2 Zn2 transport systems, permease components znuB GO:0000006,GO:0000041,GO:0003674,GO:0005215,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008324,GO:0010035,GO:0010038,GO:0010043,GO:0015075,GO:0015318,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0042221,GO:0044464,GO:0046873,GO:0046915,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662 - ko:K09816 ko02010,map02010 M00242 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15.3,3.A.1.15.5 - iEC042_1314.EC042_2026,iECABU_c1320.ECABU_c21210,iECED1_1282.ECED1_2064,iECNA114_1301.ECNA114_1921,iECSF_1327.ECSF_1717,iECUMN_1333.ECUMN_2157,iEcSMS35_1347.EcSMS35_1327,iG2583_1286.G2583_2311,iSSON_1240.SSON_1282,iYL1228.KPN_02374,ic_1306.c2273 ABC-3 k141_17121_10 1042377.AFPJ01000025_gene621 8.26e-112 326.0 COG1853@1|root,COG1853@2|Bacteria,1RDFM@1224|Proteobacteria,1RTF9@1236|Gammaproteobacteria,466VM@72275|Alteromonadaceae 1236|Gammaproteobacteria S Flavin reductase like domain - - - - - - - - - - - - Flavin_Reduct k141_17121_11 545276.KB898728_gene158 2.94e-14 71.6 COG3011@1|root,COG3011@2|Bacteria,1PV30@1224|Proteobacteria,1SCCX@1236|Gammaproteobacteria,1WZJ7@135613|Chromatiales 135613|Chromatiales S Protein of unknown function, DUF393 - - - - - - - - - - - - DUF393 k141_17121_12 1198452.Jab_1c19090 4.82e-05 51.6 COG1266@1|root,COG1266@2|Bacteria,1RJZQ@1224|Proteobacteria,2VSUQ@28216|Betaproteobacteria,476YQ@75682|Oxalobacteraceae 28216|Betaproteobacteria S CAAX protease self-immunity - - - ko:K07052 - - - - ko00000 - - - Abi k141_17121_13 1305737.JAFX01000001_gene2221 1.26e-10 62.8 COG3184@1|root,COG3184@2|Bacteria 2|Bacteria S Uncharacterized protein conserved in bacteria (DUF2059) - - - ko:K09924 - - - - ko00000 - - - DUF2059 k141_17121_14 1453501.JELR01000002_gene1066 2.77e-126 363.0 COG1999@1|root,COG1999@2|Bacteria,1RHJ8@1224|Proteobacteria,1SYEA@1236|Gammaproteobacteria,46CW7@72275|Alteromonadaceae 1236|Gammaproteobacteria S SCO1/SenC - - - ko:K07152 - - - - ko00000,ko03029 - - - SCO1-SenC k141_17121_17 1042377.AFPJ01000012_gene1388 4.63e-60 194.0 COG1999@1|root,COG1999@2|Bacteria,1N6R6@1224|Proteobacteria,1SC88@1236|Gammaproteobacteria,46868@72275|Alteromonadaceae 1236|Gammaproteobacteria S signal sequence binding - - - - - - - - - - - - - k141_17121_18 247634.GPB2148_413 9.84e-39 142.0 COG3346@1|root,COG3346@2|Bacteria,1MZUH@1224|Proteobacteria,1S8S0@1236|Gammaproteobacteria,1J6FD@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S SURF1-like protein surf1 - - ko:K14998 - - - - ko00000,ko03029 3.D.4.8 - - SURF1 k141_35023_1 218284.CCDN010000001_gene83 4.02e-77 234.0 COG1589@1|root,COG1589@2|Bacteria,1V6V5@1239|Firmicutes,4HDFD@91061|Bacilli,1ZDSW@1386|Bacillus 91061|Bacilli D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex divIB - - ko:K03589 ko04112,map04112 - - - ko00000,ko00001,ko03036 - - - FtsQ,POTRA_1 k141_19574_1 1294265.JCM21738_3040 4.63e-130 379.0 COG2233@1|root,COG2233@2|Bacteria,1TQ0A@1239|Firmicutes,4HA6X@91061|Bacilli,1ZD5W@1386|Bacillus 91061|Bacilli F Xanthine uracil ywdJ GO:0003674,GO:0005215,GO:0005345,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006863,GO:0008150,GO:0015205,GO:0015851,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0042906,GO:0042907,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072530,GO:1904823 - - - - - - - - - - Xan_ur_permease k141_26905_1 1294265.JCM21738_2731 3.58e-16 76.3 COG0109@1|root,COG0109@2|Bacteria,1TPS1@1239|Firmicutes,4HBJT@91061|Bacilli,1ZCJT@1386|Bacillus 91061|Bacilli O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group ctaB GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 M00154 R07411 RC01786 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 - - iSB619.SA_RS05465 UbiA k141_26905_2 1294265.JCM21738_2730 2.33e-32 119.0 COG1612@1|root,COG1612@2|Bacteria,1TR4W@1239|Firmicutes,4HC12@91061|Bacilli,1ZC0K@1386|Bacillus 91061|Bacilli O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group ctaA GO:0000003,GO:0003674,GO:0003824,GO:0008150,GO:0009987,GO:0016043,GO:0017004,GO:0019954,GO:0022607,GO:0030436,GO:0032502,GO:0034622,GO:0043933,GO:0043934,GO:0044085,GO:0065003,GO:0071840 - ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 M00154 R07412 RC00769 ko00000,ko00001,ko00002,ko03029 3.D.4.4 - iSB619.SA_RS05460,iYO844.BSU14870 COX15-CtaA k141_5359_1 1294265.JCM21738_2818 3.78e-147 422.0 COG0477@1|root,COG2814@2|Bacteria,1TS6K@1239|Firmicutes,4HB1V@91061|Bacilli,1ZB90@1386|Bacillus 91061|Bacilli EGP COG0477 Permeases of the major facilitator superfamily tetA_3 - - - - - - - - - - - MFS_1,MFS_1_like,Sugar_tr k141_32489_1 218284.CCDN010000001_gene1892 2.39e-98 286.0 COG0779@1|root,COG0779@2|Bacteria,1V6KT@1239|Firmicutes,4HH88@91061|Bacilli,1ZG6S@1386|Bacillus 91061|Bacilli S Required for maturation of 30S ribosomal subunits rimP GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - ko:K09748 - - - - ko00000,ko03009 - - - DUF150,DUF150_C k141_14712_1 218284.CCDN010000006_gene3749 1.37e-126 370.0 COG1486@1|root,COG1486@2|Bacteria,1TQ9I@1239|Firmicutes,4H9Z4@91061|Bacilli,1ZC6U@1386|Bacillus 91061|Bacilli G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases - - 3.2.1.86 ko:K01222 ko00010,ko00500,map00010,map00500 - R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 - GT4 - Glyco_hydro_4,Glyco_hydro_4C k141_2853_1 218284.CCDN010000002_gene2750 2.93e-91 276.0 COG1173@1|root,COG1173@2|Bacteria,1V21B@1239|Firmicutes,4HJ5Y@91061|Bacilli,1ZFPK@1386|Bacillus 91061|Bacilli EP ABC transporter (permease) - - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 k141_664_1 768066.HELO_1135 6.11e-05 44.3 COG3181@1|root,COG3181@2|Bacteria,1MXEX@1224|Proteobacteria,1RPKH@1236|Gammaproteobacteria,1XJ1G@135619|Oceanospirillales 135619|Oceanospirillales S C4-dicarboxylate ABC transporter substrate-binding protein - - - ko:K07795 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.80.1 - - TctC k141_664_2 768066.HELO_1136 5.57e-85 253.0 2EFUW@1|root,339M2@2|Bacteria 2|Bacteria S Tripartite tricarboxylate transporter TctB family - - - ko:K07794 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.80.1 - - TctB k141_7596_1 1123322.KB904683_gene4838 8.93e-24 105.0 COG1200@1|root,COG1200@2|Bacteria,2GKA3@201174|Actinobacteria 201174|Actinobacteria L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) recG GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecG_wedge,tRNA_anti-codon k141_18449_1 1121121.KB894298_gene4007 3.18e-49 166.0 COG1540@1|root,COG1540@2|Bacteria,1TR8X@1239|Firmicutes,4H9PF@91061|Bacilli,26QYJ@186822|Paenibacillaceae 91061|Bacilli S Belongs to the UPF0271 (lamB) family ycsF - - ko:K07160 - - - - ko00000 - - - LamB_YcsF k141_13763_2 1034347.CAHJ01000039_gene4690 2.53e-05 43.5 2EJUP@1|root,33DJB@2|Bacteria,1VMIR@1239|Firmicutes,4HRA6@91061|Bacilli,1ZK02@1386|Bacillus 91061|Bacilli S YqzM-like protein - - - - - - - - - - - - YqzM k141_26906_1 1178540.BA70_02505 5.43e-30 115.0 2DZ9Y@1|root,32V70@2|Bacteria,1VA6H@1239|Firmicutes,4HKSG@91061|Bacilli,1ZHSJ@1386|Bacillus 91061|Bacilli S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) yhcN - - - - - - - - - - - Spore_YhcN_YlaJ k141_19575_2 491205.JARQ01000007_gene3068 2.39e-37 142.0 2EMFS@1|root,33F4H@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - DUF4280 k141_11300_1 479434.Sthe_3409 2.38e-80 253.0 COG1032@1|root,COG1032@2|Bacteria,2G6ZI@200795|Chloroflexi 200795|Chloroflexi C SMART Elongator protein 3 MiaB NifB - - 1.21.98.3 ko:K04034 ko00860,ko01100,ko01110,map00860,map01100,map01110 - R06268,R06269,R06270 RC00741,RC01491,RC01492 ko00000,ko00001,ko01000 - - - B12-binding,Radical_SAM k141_10137_1 1042377.AFPJ01000055_gene957 6.33e-294 823.0 COG2366@1|root,COG2366@2|Bacteria,1MVMH@1224|Proteobacteria,1RMPX@1236|Gammaproteobacteria,464PP@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG2366 Protein related to penicillin acylase pvdQ - 3.5.1.97 ko:K07116 - - - - ko00000,ko01000 - - - Penicil_amidase k141_37445_1 1279017.AQYJ01000026_gene397 3.78e-136 396.0 COG0665@1|root,COG0665@2|Bacteria,1N1TN@1224|Proteobacteria,1RPIZ@1236|Gammaproteobacteria,466AB@72275|Alteromonadaceae 1236|Gammaproteobacteria E FAD dependent oxidoreductase thiO - 1.4.3.19 ko:K03153 ko00730,ko01100,map00730,map01100 - R07463 RC01788 ko00000,ko00001,ko01000 - - - DAO k141_1765_2 1127673.GLIP_2702 0.000772 44.7 COG1595@1|root,COG1595@2|Bacteria 2|Bacteria K DNA-templated transcription, initiation - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_11529_2 1037409.BJ6T_82290 1.12e-35 129.0 2CFS9@1|root,32Y2C@2|Bacteria,1NNYX@1224|Proteobacteria,2UYM9@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_27135_1 404589.Anae109_1720 5.01e-61 203.0 COG2270@1|root,COG2270@2|Bacteria,1MWXB@1224|Proteobacteria,42N2B@68525|delta/epsilon subdivisions,2WJS9@28221|Deltaproteobacteria,2YVFZ@29|Myxococcales 28221|Deltaproteobacteria S Major facilitator - - - ko:K06902 ko04138,map04138 - - - ko00000,ko00001,ko02000,ko04131 2.A.1.24,9.A.15.1 - - ATG22 k141_17290_2 1223543.GP2_033_00720 1.19e-99 306.0 COG3328@1|root,COG3328@2|Bacteria,2GM8F@201174|Actinobacteria,4GAKR@85026|Gordoniaceae 201174|Actinobacteria L Transposase, Mutator family - - - - - - - - - - - - Transposase_mut k141_29166_1 1379270.AUXF01000003_gene3485 1.6e-49 171.0 COG0500@1|root,COG2226@2|Bacteria,1ZSNE@142182|Gemmatimonadetes 142182|Gemmatimonadetes H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) menG - 2.1.1.163,2.1.1.201 ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116,M00117 R04990,R04993,R06859,R08774,R09736 RC00003,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000 - - - Ubie_methyltran k141_6697_1 218284.CCDN010000001_gene425 1.24e-15 74.3 2DM3D@1|root,31J5I@2|Bacteria,1UHTM@1239|Firmicutes,4IS9A@91061|Bacilli,1ZS3H@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2785) - - - - - - - - - - - - DUF2785 k141_17314_1 1177154.Y5S_03231 3.65e-47 160.0 COG1305@1|root,COG1305@2|Bacteria,1R4TK@1224|Proteobacteria,1RYNT@1236|Gammaproteobacteria,1XJ4C@135619|Oceanospirillales 135619|Oceanospirillales E transglutaminase-like - - - - - - - - - - - - Transglut_core k141_36220_1 218284.CCDN010000001_gene920 4.32e-21 99.4 COG5412@1|root,COG5412@2|Bacteria,1TQ28@1239|Firmicutes,4HCMX@91061|Bacilli,1ZEVU@1386|Bacillus 91061|Bacilli D Phage tail tape measure protein, TP901 family - - - - - - - - - - - - PhageMin_Tail k141_32680_1 1294265.JCM21738_4092 2.62e-135 408.0 COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,4HAWB@91061|Bacilli,1ZAQK@1386|Bacillus 91061|Bacilli J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS - 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1,zf-FPG_IleRS k141_1788_1 1116375.VEJY3_05370 2.34e-81 266.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1XSPS@135623|Vibrionales 135623|Vibrionales U COG0841 Cation multidrug efflux pump acrB - - ko:K18138 ko01501,ko01503,map01501,map01503 M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2 - - ACR_tran k141_1788_2 1116375.VEJY3_05375 1.84e-72 221.0 COG1846@1|root,COG1846@2|Bacteria,1QJQI@1224|Proteobacteria,1THRQ@1236|Gammaproteobacteria,1XXBP@135623|Vibrionales 135623|Vibrionales K helix_turn_helix multiple antibiotic resistance protein - - - - - - - - - - - - MarR k141_1788_3 1219076.N646_0143 1.09e-181 511.0 COG0679@1|root,COG0679@2|Bacteria,1N1X9@1224|Proteobacteria,1RMV0@1236|Gammaproteobacteria,1XSDV@135623|Vibrionales 135623|Vibrionales S Membrane transport protein - - - ko:K07088 - - - - ko00000 - - - Mem_trans k141_1788_4 945550.VISI1226_00810 2.75e-278 774.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RS71@1236|Gammaproteobacteria,1XWDP@135623|Vibrionales 135623|Vibrionales NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - 4HB_MCP_1,MCPsignal k141_18711_1 218284.CCDN010000001_gene1145 4.99e-14 71.2 COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,4HA13@91061|Bacilli,1ZCMB@1386|Bacillus 91061|Bacilli E Aminotransferase aspB GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769,GO:0047297 2.6.1.1,2.6.1.14 ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 - R00355,R00694,R00734,R00896,R01346,R02433,R02619,R05052 RC00006,RC00025 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 k141_18711_2 218284.CCDN010000001_gene1146 5.44e-314 855.0 COG0017@1|root,COG0017@2|Bacteria,1TP38@1239|Firmicutes,4H9YH@91061|Bacilli,1ZC51@1386|Bacillus 91061|Bacilli J asparaginyl-tRNA asnS GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.22 ko:K01893 ko00970,map00970 M00359,M00360 R03648 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2,tRNA_anti-codon k141_12799_1 1161401.ASJA01000013_gene767 2.41e-100 304.0 COG0701@1|root,COG0701@2|Bacteria,1NC9F@1224|Proteobacteria,2U1D0@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Predicted permease - - - ko:K07089 - - - - ko00000 - - - ArsP_1 k141_11550_1 218284.CCDN010000001_gene738 6.19e-243 672.0 COG0621@1|root,COG0621@2|Bacteria,1TPBR@1239|Firmicutes,4HBYZ@91061|Bacilli,1ZB8Q@1386|Bacillus 91061|Bacilli J ribosomal protein S12 methylthiotransferase yqeV GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035598,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360 2.8.4.5 ko:K18707 - - R10649 RC00003,RC03221 ko00000,ko01000,ko03016 - - - Radical_SAM,TRAM,UPF0004 k141_20835_1 218284.CCDN010000002_gene2167 9.16e-153 431.0 COG1030@1|root,COG1030@2|Bacteria,1V6UR@1239|Firmicutes,4HJIN@91061|Bacilli,1ZFVS@1386|Bacillus 91061|Bacilli - - M1-693 - - - - - - - - - - - TspO_MBR k141_19766_1 1279017.AQYJ01000026_gene228 0.0 1355.0 COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,1RN05@1236|Gammaproteobacteria,464MR@72275|Alteromonadaceae 1236|Gammaproteobacteria S Insulinase (Peptidase family M16) ptrA - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C k141_19766_2 1121374.KB891586_gene2742 5.08e-238 660.0 COG0189@1|root,COG0189@2|Bacteria,1MX62@1224|Proteobacteria,1RRS7@1236|Gammaproteobacteria 1236|Gammaproteobacteria HJ COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase) - - - - - - - - - - - - RimK,TrkA_C k141_19766_3 1219065.VPR01S_01_02990 9.66e-191 543.0 COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,1RMYY@1236|Gammaproteobacteria,1XWB0@135623|Vibrionales 135623|Vibrionales M Mechanosensitive ion channel - - - - - - - - - - - - MS_channel,MscS_TM k141_19766_4 1279017.AQYJ01000026_gene225 2.54e-107 313.0 COG0625@1|root,COG0625@2|Bacteria,1Q05U@1224|Proteobacteria,1RZZS@1236|Gammaproteobacteria,4666H@72275|Alteromonadaceae 1236|Gammaproteobacteria O Glutathione S-transferase - - - - - - - - - - - - GST_C,GST_C_2,GST_N_3 k141_19766_5 1279017.AQYJ01000026_gene224 2.41e-241 672.0 COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,1RQRP@1236|Gammaproteobacteria,4653Y@72275|Alteromonadaceae 1236|Gammaproteobacteria Q COG1228 Imidazolonepropionase and related amidohydrolases - - - - - - - - - - - - Amidohydro_1 k141_19766_6 1042377.AFPJ01000019_gene2544 1.3e-83 257.0 COG2968@1|root,COG2968@2|Bacteria,1RH7T@1224|Proteobacteria,1RP7T@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Oxidative stress defense protein bp26 - - ko:K09807 - - - - ko00000 - - - SIMPL k141_19766_7 1279017.AQYJ01000026_gene221 3.43e-200 563.0 COG0520@1|root,COG0520@2|Bacteria,1PJFE@1224|Proteobacteria,1RRJK@1236|Gammaproteobacteria,465WY@72275|Alteromonadaceae 1236|Gammaproteobacteria E Selenocysteine lyase - - - - - - - - - - - - Aminotran_5 k141_19766_9 1453501.JELR01000001_gene2023 1.19e-199 560.0 COG1752@1|root,COG1752@2|Bacteria,1MU6Z@1224|Proteobacteria,1RPW6@1236|Gammaproteobacteria,4669M@72275|Alteromonadaceae 1236|Gammaproteobacteria S Esterase of the alpha-beta hydrolase superfamily - - - - - - - - - - - - Patatin k141_19766_10 1279017.AQYJ01000026_gene218 8.66e-129 369.0 COG1802@1|root,COG1802@2|Bacteria,1MVXM@1224|Proteobacteria,1S0ME@1236|Gammaproteobacteria,46B3N@72275|Alteromonadaceae 1236|Gammaproteobacteria K FCD - - - - - - - - - - - - FCD,GntR k141_19766_11 1453501.JELR01000001_gene2025 3.05e-37 128.0 2C9TE@1|root,32RPW@2|Bacteria,1N8DZ@1224|Proteobacteria,1SF18@1236|Gammaproteobacteria,46BPG@72275|Alteromonadaceae 1236|Gammaproteobacteria - - VL23_07270 - - - - - - - - - - - - k141_19766_12 1042377.AFPJ01000019_gene2538 3.19e-28 114.0 COG4242@1|root,COG4242@2|Bacteria,1R5TW@1224|Proteobacteria,1RYMR@1236|Gammaproteobacteria 1236|Gammaproteobacteria PQ Belongs to the peptidase S51 family - - - - - - - - - - - - PPC,Peptidase_S51 k141_7772_1 552811.Dehly_0397 4.74e-87 274.0 COG0034@1|root,COG0034@2|Bacteria,2G61T@200795|Chloroflexi,34CJ3@301297|Dehalococcoidia 301297|Dehalococcoidia F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine purF - 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase_7,Pribosyltran k141_14890_1 83406.HDN1F_35800 1.11e-05 48.9 COG1376@1|root,COG1388@1|root,COG1376@2|Bacteria,COG1388@2|Bacteria,1MVYT@1224|Proteobacteria,1RMNC@1236|Gammaproteobacteria,1J5RU@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M L,D-transpeptidase catalytic domain ycfS GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005575,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0008236,GO:0008238,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016746,GO:0016755,GO:0016787,GO:0016807,GO:0017171,GO:0018104,GO:0019538,GO:0030203,GO:0034645,GO:0042546,GO:0042597,GO:0043164,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044464,GO:0070004,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071972,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 - ko:K16291,ko:K19234,ko:K19235,ko:K19236 ko01503,map01503 - - - ko00000,ko00001,ko01002,ko01011 - - - LysM,YkuD k141_25829_1 1279017.AQYJ01000028_gene2336 2.52e-193 550.0 COG4579@1|root,COG4579@2|Bacteria,1MVRB@1224|Proteobacteria,1RMC2@1236|Gammaproteobacteria,4655G@72275|Alteromonadaceae 1236|Gammaproteobacteria F Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation aceK GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004721,GO:0005488,GO:0005524,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008772,GO:0009987,GO:0016208,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0017076,GO:0018105,GO:0018193,GO:0018209,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050790,GO:0065007,GO:0065009,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.11.5 ko:K00906 - - - - ko00000,ko01000 - - - AceK k141_34027_1 1116375.VEJY3_16066 7.13e-64 201.0 COG2375@1|root,COG2375@2|Bacteria,1R4TD@1224|Proteobacteria,1RY01@1236|Gammaproteobacteria,1XTJW@135623|Vibrionales 135623|Vibrionales P Siderophore-interacting protein - - - - - - - - - - - - FAD_binding_9,SIP k141_34027_2 223926.28808226 2.56e-293 799.0 COG0823@1|root,COG0823@2|Bacteria,1MUK9@1224|Proteobacteria,1RNR8@1236|Gammaproteobacteria,1XUFH@135623|Vibrionales 135623|Vibrionales U Oligogalacturonate lyase - - 4.2.2.6 ko:K01730 ko00040,map00040 - R04382 RC02124,RC02427 ko00000,ko00001,ko01000 - - - Pectate_lyase22 k141_34027_3 675813.VIB_002457 0.0 970.0 COG0591@1|root,COG0591@2|Bacteria,1MW6E@1224|Proteobacteria,1RXYK@1236|Gammaproteobacteria,1XSDY@135623|Vibrionales 135623|Vibrionales E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - - - - - - - - - - SSF k141_34027_4 1209072.ALBT01000007_gene2785 2.28e-61 208.0 COG4677@1|root,COG4677@2|Bacteria,1QBYN@1224|Proteobacteria,1RNSE@1236|Gammaproteobacteria,1FGGT@10|Cellvibrio 1236|Gammaproteobacteria G Pectinesterase pemA GO:0005575,GO:0005576 3.1.1.11 ko:K01051 ko00040,ko01100,map00040,map01100 M00081 R02362 RC00460,RC00461 ko00000,ko00001,ko00002,ko01000 - - - Pectinesterase k141_22095_1 218284.CCDN010000001_gene796 3.76e-111 343.0 COG0297@1|root,COG0297@2|Bacteria,1UHYC@1239|Firmicutes,4ISUZ@91061|Bacilli,1ZD41@1386|Bacillus 91061|Bacilli G Starch synthase catalytic domain - - - - - - - - - - - - Glyco_hydro_57,Glyco_transf_4,Glycos_transf_1 k141_9123_1 1403313.AXBR01000014_gene2292 4.77e-34 124.0 COG0726@1|root,COG0726@2|Bacteria,1TPWK@1239|Firmicutes,4HEQ2@91061|Bacilli,1ZPWD@1386|Bacillus 91061|Bacilli G Polysaccharide deacetylase - - - - - - - - - - - - Polysacc_deac_1 k141_1789_1 218284.CCDN010000011_gene4423 3.73e-96 301.0 COG1305@1|root,COG1305@2|Bacteria,1TP8K@1239|Firmicutes,4HB2E@91061|Bacilli,1ZBUN@1386|Bacillus 91061|Bacilli E COG1305 Transglutaminase-like enzymes yebA - - - - - - - - - - - DUF4129,Transglut_core k141_14018_1 218284.CCDN010000005_gene3203 2e-154 436.0 COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,4HCH3@91061|Bacilli,1ZAXG@1386|Bacillus 91061|Bacilli I Belongs to the enoyl-CoA hydratase isomerase family yngF - - - - - - - - - - - ECH_1 k141_14018_3 1395513.P343_14925 3.69e-19 89.4 29H5Q@1|root,31K0D@2|Bacteria,1V94V@1239|Firmicutes,4HK2Z@91061|Bacilli 91061|Bacilli S Nuclease-related domain - - - - - - - - - - - - NERD k141_16151_1 218284.CCDN010000011_gene4424 2.23e-191 541.0 COG0519@1|root,COG0519@2|Bacteria,1TPG8@1239|Firmicutes,4HA7Q@91061|Bacilli,1ZB6Z@1386|Bacillus 91061|Bacilli F Catalyzes the synthesis of GMP from XMP guaA GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase,GMP_synt_C,NAD_synthase k141_36221_1 1453501.JELR01000005_gene1785 1.8e-121 361.0 COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,1RNKA@1236|Gammaproteobacteria,464PF@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source nadE - 6.3.1.5,6.3.5.1 ko:K01916,ko:K01950 ko00760,ko01100,map00760,map01100 M00115 R00189,R00257 RC00010,RC00100 ko00000,ko00001,ko00002,ko01000 - - - CN_hydrolase,NAD_synthase k141_10372_1 218284.CCDN010000001_gene978 5.77e-81 245.0 COG0584@1|root,COG0584@2|Bacteria,1V3W4@1239|Firmicutes,4HFNQ@91061|Bacilli,1ZAVP@1386|Bacillus 91061|Bacilli C glycerophosphoryl diester phosphodiesterase yqiK - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - GDPD k141_11551_1 1382359.JIAL01000001_gene1741 4.42e-74 242.0 COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria,3Y5CQ@57723|Acidobacteria,2JKVX@204432|Acidobacteriia 204432|Acidobacteriia C Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S - - 1.5.5.1 ko:K00311 - - - - ko00000,ko01000 - - - ETF_QO k141_839_1 218284.CCDN010000001_gene638 2.43e-98 286.0 COG4492@1|root,COG4492@2|Bacteria,1VAJ9@1239|Firmicutes,4HFRC@91061|Bacilli,1ZFNK@1386|Bacillus 91061|Bacilli S Belongs to the UPF0735 family pheB - 5.4.99.5 ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024,M00025 R01715 RC03116 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU27910 ACT,ACT_4 k141_14891_2 218284.CCDN010000001_gene1866 3.53e-88 267.0 COG4603@1|root,COG4603@2|Bacteria,1TP1F@1239|Firmicutes,4H9VE@91061|Bacilli,1ZCTP@1386|Bacillus 91061|Bacilli S Belongs to the binding-protein-dependent transport system permease family yufP GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015749,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0034219,GO:0044425,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 - ko:K02057 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - BPD_transp_2 k141_9124_1 1279017.AQYJ01000028_gene2531 0.000212 48.9 COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,1RMC5@1236|Gammaproteobacteria,4653C@72275|Alteromonadaceae 1236|Gammaproteobacteria V COG1131 ABC-type multidrug transport system, ATPase component - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_25830_1 218284.CCDN010000002_gene2212 1.2e-24 102.0 COG4146@1|root,COG4146@2|Bacteria,1UHPR@1239|Firmicutes,4HDFI@91061|Bacilli,1ZDJB@1386|Bacillus 91061|Bacilli S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - ko:K03307 - - - - ko00000 2.A.21 - - SSF k141_25830_2 218284.CCDN010000002_gene2211 2.21e-16 78.2 COG1972@1|root,COG1972@2|Bacteria,1TRSK@1239|Firmicutes,4I95Q@91061|Bacilli,1ZEBU@1386|Bacillus 91061|Bacilli F Na+ dependent nucleoside transporter C-terminus - - - ko:K03317 - - - - ko00000 2.A.41 - - Nucleos_tra2_C,Nucleos_tra2_N k141_4263_1 218284.CCDN010000008_gene4204 3.34e-151 431.0 COG1363@1|root,COG1363@2|Bacteria,1TNZT@1239|Firmicutes,4H9SM@91061|Bacilli,1ZAXE@1386|Bacillus 91061|Bacilli G COG1363 Cellulase M and related proteins pepA - 3.4.11.7 ko:K01261,ko:K01269 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M42 k141_12801_1 1279017.AQYJ01000027_gene1659 1e-58 191.0 COG0725@1|root,COG0725@2|Bacteria,1MVNA@1224|Proteobacteria,1RN71@1236|Gammaproteobacteria,4675T@72275|Alteromonadaceae 1236|Gammaproteobacteria P molybdenum ABC transporter, periplasmic modA - - ko:K02020 ko02010,map02010 M00189 - - ko00000,ko00001,ko00002,ko02000 3.A.1.8 - - SBP_bac_11 k141_11552_1 218284.CCDN010000002_gene2609 2.6e-58 192.0 COG1173@1|root,COG1173@2|Bacteria,1V21B@1239|Firmicutes,4HJ5Y@91061|Bacilli,1ZFPK@1386|Bacillus 91061|Bacilli EP ABC transporter (permease) - - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 k141_18715_2 935837.JAEK01000009_gene3559 2.67e-34 131.0 COG4325@1|root,COG4325@2|Bacteria,1TSID@1239|Firmicutes,4HDM1@91061|Bacilli,1ZE04@1386|Bacillus 91061|Bacilli S Predicted membrane protein (DUF2254) - - - - - - - - - - - - DUF2254 k141_16152_1 1178482.BJB45_10975 5.47e-12 63.9 COG0235@1|root,COG0235@2|Bacteria,1MW7B@1224|Proteobacteria,1RS8X@1236|Gammaproteobacteria,1XP8H@135619|Oceanospirillales 135619|Oceanospirillales G Class II Aldolase and Adducin N-terminal domain - - 4.1.1.104 ko:K22130 - - - - ko00000,ko01000 - - - Aldolase_II k141_16152_2 1166948.JPZL01000004_gene90 6.42e-107 321.0 COG3395@1|root,COG3395@2|Bacteria,1MW4G@1224|Proteobacteria,1RN8I@1236|Gammaproteobacteria,1XN9V@135619|Oceanospirillales 135619|Oceanospirillales S Putative nucleotide-binding of sugar-metabolising enzyme - - 2.7.1.217 ko:K21948 - - R11706,R11707 - ko00000,ko01000 - - - DUF1357_C,DUF1537 k141_9125_1 1116375.VEJY3_03225 8.96e-133 399.0 COG0457@1|root,COG0457@2|Bacteria,1RDRI@1224|Proteobacteria,1S3PB@1236|Gammaproteobacteria,1XTIH@135623|Vibrionales 135623|Vibrionales S COG0457 FOG TPR repeat - - - - - - - - - - - - TPR_12 k141_34028_1 935837.JAEK01000055_gene1518 1.71e-10 61.2 COG2057@1|root,COG2057@2|Bacteria,1TNY5@1239|Firmicutes,4HB5T@91061|Bacilli,1ZQEG@1386|Bacillus 91061|Bacilli I CoA-transferase - - 2.8.3.8,2.8.3.9 ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 - R01179,R01359,R01365,R07832 RC00012,RC00014 ko00000,ko00001,ko01000 - - - CoA_trans k141_34028_2 665959.HMPREF1013_01935 1.68e-104 315.0 COG0624@1|root,COG0624@2|Bacteria,1TQS9@1239|Firmicutes,4HDHW@91061|Bacilli,1ZBDC@1386|Bacillus 91061|Bacilli E Acetylornithine deacetylase yodQ - 3.5.1.16,3.5.1.18 ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R00669,R02734,R09107 RC00064,RC00090,RC00300 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20,Peptidase_M28 k141_3003_1 218284.CCDN010000006_gene3632 3.74e-83 252.0 COG2755@1|root,COG2755@2|Bacteria,1UZKM@1239|Firmicutes,4HVJ0@91061|Bacilli,1ZEST@1386|Bacillus 91061|Bacilli E GDSL-like Lipase/Acylhydrolase - - - - - - - - - - - - Lipase_GDSL_2 k141_4264_1 1294265.JCM21738_1328 8.23e-108 322.0 COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4HBBB@91061|Bacilli,1ZCKA@1386|Bacillus 91061|Bacilli M Penicillin-binding Protein pbpD - 2.4.1.129,3.4.16.4 ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase k141_14021_1 218284.CCDN010000001_gene723 8.22e-67 224.0 COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,4H9M4@91061|Bacilli,1ZBWR@1386|Bacillus 91061|Bacilli S Competence protein ComEC comEC - - ko:K02238 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - Competence,DUF4131,Lactamase_B k141_29207_1 1279017.AQYJ01000025_gene679 1.76e-163 474.0 COG0596@1|root,COG0596@2|Bacteria,1R6KU@1224|Proteobacteria,1RNTQ@1236|Gammaproteobacteria,4692F@72275|Alteromonadaceae 1236|Gammaproteobacteria S TAP-like protein - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_4 k141_24510_2 1234364.AMSF01000095_gene2627 8.63e-20 89.7 COG0446@1|root,COG0446@2|Bacteria,1Q0P8@1224|Proteobacteria,1T1NQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Tryptophan halogenase - - 1.14.19.9 ko:K14266 ko00404,ko01130,map00404,map01130 M00789,M00790 R09570 RC00949 ko00000,ko00001,ko00002,ko01000 - - - Trp_halogenase k141_12802_1 265729.GS18_0206620 9.84e-41 142.0 28IFV@1|root,2Z8HF@2|Bacteria,1VC8J@1239|Firmicutes,4HMPA@91061|Bacilli,1ZIEE@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_9126_1 84531.JMTZ01000102_gene684 1.6e-12 68.2 COG0744@1|root,COG0744@2|Bacteria,1RDAQ@1224|Proteobacteria,1RMGB@1236|Gammaproteobacteria,1X4AQ@135614|Xanthomonadales 135614|Xanthomonadales M Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors mtgA - 2.4.1.129 ko:K03814 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly k141_14894_1 218284.CCDN010000006_gene3623 9.86e-116 360.0 COG0457@1|root,COG0457@2|Bacteria,1TSH7@1239|Firmicutes,4HACN@91061|Bacilli,1ZBDH@1386|Bacillus 91061|Bacilli M Tetratricopeptide repeat - - - - - - - - - - - - - k141_23443_1 935837.JAEK01000015_gene5020 3.26e-50 165.0 COG0500@1|root,COG0500@2|Bacteria,1V0PR@1239|Firmicutes,4HB7J@91061|Bacilli,1ZEGC@1386|Bacillus 91061|Bacilli Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_11 k141_23443_2 218284.CCDN010000001_gene486 7.31e-29 107.0 COG3896@1|root,COG3896@2|Bacteria,1U3UE@1239|Firmicutes,4IDMG@91061|Bacilli,1ZKNE@1386|Bacillus 91061|Bacilli V Chloramphenicol phosphotransferase-like protein - - - - - - - - - - - - CPT k141_7776_1 84751.XP_007877660.1 1.12e-12 65.9 COG0278@1|root,KOG0911@2759|Eukaryota,3A1XT@33154|Opisthokonta,3P2U5@4751|Fungi,3V1AG@5204|Basidiomycota,3N1C3@452284|Ustilaginomycotina 4751|Fungi O Glutaredoxin GRX5 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006790,GO:0006807,GO:0006950,GO:0006970,GO:0006979,GO:0008150,GO:0008152,GO:0009628,GO:0009987,GO:0010467,GO:0015035,GO:0015036,GO:0015037,GO:0015038,GO:0016043,GO:0016226,GO:0016491,GO:0016667,GO:0016740,GO:0016782,GO:0019538,GO:0022607,GO:0031163,GO:0031974,GO:0033554,GO:0034599,GO:0036455,GO:0042221,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044085,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044571,GO:0044572,GO:0048037,GO:0050896,GO:0051186,GO:0051536,GO:0051537,GO:0051540,GO:0051604,GO:0051716,GO:0055114,GO:0070013,GO:0070887,GO:0071704,GO:0071840,GO:0097428,GO:0106034,GO:1901564 - ko:K07390 - - - - ko00000,ko03029,ko03110 - - - Glutaredoxin k141_7776_2 1385515.N791_02545 2.49e-49 171.0 COG2234@1|root,COG2234@2|Bacteria,1MWBX@1224|Proteobacteria,1RYHQ@1236|Gammaproteobacteria,1X2XJ@135614|Xanthomonadales 135614|Xanthomonadales S Peptidase m28 - - - - - - - - - - - - Peptidase_M28 k141_30261_1 218284.CCDN010000008_gene4214 2.87e-11 69.7 COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,4HA1S@91061|Bacilli,1ZAYY@1386|Bacillus 91061|Bacilli D Belongs to the FtsK SpoIIIE SftA family sftA - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_SpoIIIE,Ftsk_gamma k141_32685_1 1267533.KB906735_gene4481 1.02e-68 220.0 COG2132@1|root,COG2132@2|Bacteria 2|Bacteria Q Multicopper oxidase - - 1.16.3.3,1.7.2.1 ko:K00368,ko:K22348,ko:K22349 ko00910,ko01120,map00910,map01120 M00529 R00783,R00785 RC00086 ko00000,ko00001,ko00002,ko01000 - - - Copper-bind,Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3,DUF4396 k141_24542_1 717231.Flexsi_1330 2.64e-24 105.0 COG1232@1|root,COG1232@2|Bacteria,2GF9H@200930|Deferribacteres 200930|Deferribacteres H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX - - 1.3.3.15,1.3.3.4 ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03222,R04178 RC00885 ko00000,ko00001,ko00002,ko01000 - - - Amino_oxidase k141_20854_1 565045.NOR51B_14 1.95e-07 50.8 COG1734@1|root,COG1734@2|Bacteria,1MZIB@1224|Proteobacteria,1S8SP@1236|Gammaproteobacteria,1JBI5@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria K Prokaryotic dksA/traR C4-type zinc finger ybiI - - - - - - - - - - - zf-dskA_traR k141_14924_1 1458427.BAWN01000015_gene935 1.69e-22 101.0 COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,2VHY8@28216|Betaproteobacteria,4ABJ6@80864|Comamonadaceae 28216|Betaproteobacteria NU Tfp pilus assembly protein tip-associated adhesin PilY1-like protein pilY1 - - ko:K02674 - - - - ko00000,ko02035,ko02044 - - - Neisseria_PilC k141_30277_1 991905.SL003B_3848 1.69e-115 338.0 COG2801@1|root,COG2801@2|Bacteria,1MZ45@1224|Proteobacteria,2VFQ6@28211|Alphaproteobacteria 28211|Alphaproteobacteria L leucine-zipper of insertion element IS481 - - - - - - - - - - - - HTH_32,rve k141_1817_1 1118054.CAGW01000107_gene3670 2.9e-47 156.0 COG3728@1|root,COG3728@2|Bacteria,1TU30@1239|Firmicutes,4IFTJ@91061|Bacilli,2709D@186822|Paenibacillaceae 91061|Bacilli L Terminase small subunit - - - - - - - - - - - - Terminase_2 k141_7802_1 218284.CCDN010000001_gene192 3.85e-76 235.0 COG0784@1|root,COG0835@1|root,COG0784@2|Bacteria,COG0835@2|Bacteria,1TRJU@1239|Firmicutes,4HCPT@91061|Bacilli,1ZAYA@1386|Bacillus 91061|Bacilli T Chemotaxis protein CheV cheV GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0044424,GO:0044444,GO:0044464,GO:0050896 - ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - CheW,Response_reg k141_36239_1 218284.CCDN010000001_gene135 1.16e-108 319.0 COG2066@1|root,COG2066@2|Bacteria,1TP64@1239|Firmicutes,4H9XA@91061|Bacilli,1ZBXX@1386|Bacillus 91061|Bacilli E Belongs to the glutaminase family glsA GO:0003674,GO:0003824,GO:0004359,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006543,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009064,GO:0009065,GO:0009084,GO:0009987,GO:0016053,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 3.5.1.2 ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 - R00256,R01579 RC00010,RC02798 ko00000,ko00001,ko01000 - - - Glutaminase k141_5636_2 1042377.AFPJ01000030_gene445 9.5e-40 135.0 COG4327@1|root,COG4327@2|Bacteria,1N0TK@1224|Proteobacteria,1S8V9@1236|Gammaproteobacteria,468I1@72275|Alteromonadaceae 1236|Gammaproteobacteria S membrane - - - - - - - - - - - - DUF4212 k141_29401_8 1453501.JELR01000005_gene1619 8.41e-87 279.0 COG0497@1|root,COG0497@2|Bacteria,1PAB3@1224|Proteobacteria,1RZB5@1236|Gammaproteobacteria,468PN@72275|Alteromonadaceae 1236|Gammaproteobacteria L DNA recombination - - - - - - - - - - - - - k141_29401_9 1279017.AQYJ01000029_gene3503 5.6e-98 292.0 COG2885@1|root,COG2885@2|Bacteria,1R9HA@1224|Proteobacteria,1RYNB@1236|Gammaproteobacteria,46795@72275|Alteromonadaceae 1236|Gammaproteobacteria M OmpA family - - - - - - - - - - - - OmpA k141_1059_1 1116375.VEJY3_13535 5.31e-140 397.0 COG0300@1|root,COG0300@2|Bacteria,1N19P@1224|Proteobacteria,1S0BR@1236|Gammaproteobacteria,1XU7Q@135623|Vibrionales 135623|Vibrionales S Enoyl-(Acyl carrier protein) reductase - - - - - - - - - - - - adh_short k141_1059_2 223926.28807649 1.27e-125 361.0 COG0300@1|root,COG0300@2|Bacteria,1MZSS@1224|Proteobacteria,1S9D8@1236|Gammaproteobacteria,1XTDC@135623|Vibrionales 135623|Vibrionales S KR domain - - - - - - - - - - - - adh_short k141_20000_5 903818.KI912268_gene3435 5.43e-23 91.3 COG1987@1|root,COG1987@2|Bacteria 2|Bacteria N bacterial-type flagellum assembly fliQ - - ko:K02420 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - Bac_export_3 k141_20000_6 1216932.CM240_1629 3.8e-14 77.0 COG1377@1|root,COG1684@1|root,COG1377@2|Bacteria,COG1684@2|Bacteria,1TPRP@1239|Firmicutes,248N7@186801|Clostridia,36DIJ@31979|Clostridiaceae 186801|Clostridia N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin flhB - - ko:K02401,ko:K13820 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - Bac_export_1,Bac_export_2 k141_28031_2 1123236.KB899382_gene2276 1.78e-173 519.0 COG1629@1|root,COG4771@2|Bacteria,1MVFB@1224|Proteobacteria,1RNMS@1236|Gammaproteobacteria,466BD@72275|Alteromonadaceae 1236|Gammaproteobacteria P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec k141_35493_5 1279017.AQYJ01000027_gene1798 9.37e-161 462.0 COG1195@1|root,COG1195@2|Bacteria,1MX8N@1224|Proteobacteria,1RN5P@1236|Gammaproteobacteria,466CC@72275|Alteromonadaceae 1236|Gammaproteobacteria L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP recF GO:0000731,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0018130,GO:0019438,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - ko:K03629 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - SMC_N k141_1950_2 1453501.JELR01000002_gene1471 2.62e-195 553.0 COG0845@1|root,COG0845@2|Bacteria,1PEVY@1224|Proteobacteria,1RPEQ@1236|Gammaproteobacteria,465PN@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - - - - - - - - - - Biotin_lipoyl_2,HlyD_3 k141_4408_2 1279017.AQYJ01000024_gene1045 7.11e-95 280.0 COG1778@1|root,COG1778@2|Bacteria,1RH85@1224|Proteobacteria,1S6D0@1236|Gammaproteobacteria,467ND@72275|Alteromonadaceae 1236|Gammaproteobacteria S Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate kdsC GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008781,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016311,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016791,GO:0019143,GO:0033692,GO:0034637,GO:0034645,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0070567,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 3.1.3.45 ko:K03270 ko00540,ko01100,map00540,map01100 M00063 R03350 RC00017 ko00000,ko00001,ko00002,ko01000,ko01005 - - iECO26_1355.ECO26_4302 Hydrolase_3 k141_4408_4 203122.Sde_3173 1.99e-107 323.0 COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,1RMRD@1236|Gammaproteobacteria,464C7@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0530 Ca2 Na antiporter yrbG - - ko:K07301 - - - - ko00000,ko02000 2.A.19.5 - - Na_Ca_ex k141_4408_5 1279017.AQYJ01000024_gene1048 8.49e-105 307.0 COG2854@1|root,COG2854@2|Bacteria,1NKFA@1224|Proteobacteria,1SABB@1236|Gammaproteobacteria,467R8@72275|Alteromonadaceae 1236|Gammaproteobacteria Q COG2854 ABC-type transport system involved in resistance to organic solvents, auxiliary component ttg2D - - ko:K07323 ko02010,map02010 M00210 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27.3 - - MlaC k141_11791_1 42565.FP66_05085 2.51e-73 232.0 COG0733@1|root,COG0733@2|Bacteria,1MUZJ@1224|Proteobacteria,1RPCT@1236|Gammaproteobacteria,1XIJV@135619|Oceanospirillales 135619|Oceanospirillales S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family - - - ko:K03308 - - - - ko00000 2.A.22.4,2.A.22.5 - - SNF k141_32930_1 333138.LQ50_11815 6.06e-34 119.0 2CI5E@1|root,32S7D@2|Bacteria,1VA1W@1239|Firmicutes,4HKCJ@91061|Bacilli,1ZHWY@1386|Bacillus 91061|Bacilli - - yxiS - - - - - - - - - - - - k141_32930_2 218284.CCDN010000001_gene1434 8.51e-41 142.0 2CC31@1|root,2Z920@2|Bacteria,1UZSZ@1239|Firmicutes,4HCVB@91061|Bacilli,1ZGJ7@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_23763_1 386043.lwe1689 5.41e-35 129.0 COG0803@1|root,COG0803@2|Bacteria,1TPG7@1239|Firmicutes,4H9UN@91061|Bacilli,26K2R@186820|Listeriaceae 91061|Bacilli P Belongs to the bacterial solute-binding protein 9 family adcA - - ko:K09815,ko:K09818 ko02010,map02010 M00242,M00243 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 - - ZnuA k141_9418_1 171693.BN988_03284 7.82e-28 108.0 COG0673@1|root,COG0673@2|Bacteria,1USVA@1239|Firmicutes,4HDVM@91061|Bacilli,23JUW@182709|Oceanobacillus 91061|Bacilli S Oxidoreductase family, C-terminal alpha/beta domain - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C k141_11792_1 218284.CCDN010000005_gene3347 9.74e-78 242.0 COG1972@1|root,COG1972@2|Bacteria,1TRSK@1239|Firmicutes,4HA8N@91061|Bacilli,1ZAW2@1386|Bacillus 91061|Bacilli F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family yutK GO:0003674,GO:0005215,GO:0005337,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0015858,GO:0015931,GO:0015932,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:1901264,GO:1901505,GO:1901642 - ko:K03317 - - - - ko00000 2.A.41 - iYO844.BSU32180 Gate,Nucleos_tra2_C,Nucleos_tra2_N k141_4409_1 1123393.KB891330_gene774 2.33e-07 55.5 COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,1MWHZ@1224|Proteobacteria,2VH9M@28216|Betaproteobacteria,1KSCN@119069|Hydrogenophilales 119069|Hydrogenophilales C Cytochrome C oxidase subunit II, transmembrane domain - - - - - - - - - - - - COX2,COX2_TM,Cytochrome_CBB3 k141_4409_2 1286631.X805_24390 3.64e-09 57.8 COG1629@1|root,COG4771@2|Bacteria,1MX42@1224|Proteobacteria,2VMI9@28216|Betaproteobacteria,1KNFC@119065|unclassified Burkholderiales 28216|Betaproteobacteria P TonB dependent receptor bhuR - - ko:K16087 - - - - ko00000,ko02000 1.B.14.2 - - Plug,STN,TonB_dep_Rec k141_20001_1 1305737.JAFX01000001_gene2689 2.58e-60 199.0 COG2911@1|root,COG2911@2|Bacteria,4NHAF@976|Bacteroidetes,47T04@768503|Cytophagia 976|Bacteroidetes S COG NOG10142 non supervised orthologous group - - - - - - - - - - - - Porin_2 k141_37618_1 283942.IL0684 4.88e-49 180.0 COG4643@1|root,COG4643@2|Bacteria,1N08G@1224|Proteobacteria,1RTFA@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Protein of unknown function (DUF3987) - - - - - - - - - - - - DUF3987 k141_26046_1 223926.28809345 0.0 909.0 COG0515@1|root,COG0515@2|Bacteria,1MWVZ@1224|Proteobacteria,1RQBQ@1236|Gammaproteobacteria,1Y2F6@135623|Vibrionales 135623|Vibrionales T Protein tyrosine kinase VPA1044 - - - - - - - - - - - Pkinase k141_26046_2 223926.28809344 8.23e-176 502.0 COG1716@1|root,COG3456@1|root,COG1716@2|Bacteria,COG3456@2|Bacteria,1R3R7@1224|Proteobacteria,1S0GX@1236|Gammaproteobacteria,1Y2R3@135623|Vibrionales 135623|Vibrionales T Forkhead associated domain - - - ko:K11894 - - - - ko00000,ko02044 3.A.23.1 - - FHA k141_26046_3 223926.28809343 2.23e-83 248.0 COG3521@1|root,COG3521@2|Bacteria,1N80I@1224|Proteobacteria,1SC9V@1236|Gammaproteobacteria,1XXFG@135623|Vibrionales 135623|Vibrionales S Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 vasD - - ko:K11906 ko03070,map03070 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - T6SS-SciN k141_26046_4 223926.28809342 1.05e-241 673.0 COG3522@1|root,COG3522@2|Bacteria,1MXKE@1224|Proteobacteria,1RNCB@1236|Gammaproteobacteria,1XSC6@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria - - - ko:K11893 ko02025,map02025 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - T6SS_VasE k141_26046_5 223926.28809341 6.93e-242 672.0 COG1360@1|root,COG3455@1|root,COG1360@2|Bacteria,COG3455@2|Bacteria,1MU13@1224|Proteobacteria,1S2PW@1236|Gammaproteobacteria,1XT7V@135623|Vibrionales 135623|Vibrionales N VI Secretion - - - ko:K11892 ko03070,map03070 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - DotU,OmpA k141_26046_6 223926.28809340 2.7e-97 312.0 COG3523@1|root,COG3523@2|Bacteria,1MV3D@1224|Proteobacteria,1RPQ2@1236|Gammaproteobacteria,1XSAX@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria - - - ko:K11891 ko02025,ko03070,map02025,map03070 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - IcmF-related,IcmF_C,ImcF-related_N k141_1062_2 1274524.BSONL12_06458 1.45e-36 124.0 COG3655@1|root,COG3655@2|Bacteria,1VESP@1239|Firmicutes,4HKR7@91061|Bacilli,1ZHUY@1386|Bacillus 91061|Bacilli K Transcriptional regulator yozG - - ko:K07727 - - - - ko00000,ko03000 - - - HTH_26 k141_1062_3 1285586.H131_01648 8.2e-24 94.4 293T3@1|root,2ZR8H@2|Bacteria,1V593@1239|Firmicutes,4HG8Q@91061|Bacilli,3IYD9@400634|Lysinibacillus 91061|Bacilli S Protein of unknown function (DUF2975) - - - - - - - - - - - - DUF2975 k141_15109_1 1042377.AFPJ01000032_gene2776 1.31e-31 116.0 2940Y@1|root,2ZRFS@2|Bacteria,1RF8A@1224|Proteobacteria,1RZCB@1236|Gammaproteobacteria 1236|Gammaproteobacteria U L-alanine exporter AlaE alaE GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015077,GO:0015078,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015562,GO:0015672,GO:0015711,GO:0015804,GO:0015807,GO:0015808,GO:0015849,GO:0016020,GO:0022804,GO:0022857,GO:0022890,GO:0032328,GO:0034220,GO:0034639,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:0098660,GO:0098662,GO:1902475,GO:1902600,GO:1903825,GO:1905039 - - - - - - - - - - AlaE k141_15109_2 1279017.AQYJ01000020_gene1305 3.51e-82 249.0 COG0796@1|root,COG0796@2|Bacteria 2|Bacteria M Provides the (R)-glutamate required for cell wall biosynthesis - - 5.1.1.3 ko:K01776 ko00471,ko01100,map00471,map01100 - R00260 RC00302 ko00000,ko00001,ko01000,ko01011 - - - Asp_Glu_race k141_4410_1 471223.GWCH70_2556 3.55e-52 176.0 COG4972@1|root,COG4972@2|Bacteria,1TSTG@1239|Firmicutes,4HFQU@91061|Bacilli,1WHV3@129337|Geobacillus 91061|Bacilli NU Type IV pilus assembly protein PilM; - - - ko:K02662,ko:K02663 - - - - ko00000,ko02035,ko02044 - - - PilM_2 k141_28033_1 1453501.JELR01000002_gene112 1.81e-118 344.0 COG4544@1|root,COG4544@2|Bacteria,1MZQU@1224|Proteobacteria,1S9RP@1236|Gammaproteobacteria,467W8@72275|Alteromonadaceae 1236|Gammaproteobacteria S Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division - - - ko:K13053,ko:K14160 - - - - ko00000,ko03036,ko03400 - - - RecA,SulA k141_20002_1 1117379.BABA_15877 1.11e-55 183.0 2AUKD@1|root,31K93@2|Bacteria,1V6PK@1239|Firmicutes,4HHBG@91061|Bacilli,1ZQRQ@1386|Bacillus 91061|Bacilli S Stage II sporulation protein R (spore_II_R) spoIIR - - ko:K06387 - - - - ko00000 - - - Spore_II_R k141_29403_1 1279017.AQYJ01000028_gene2334 2.78e-285 796.0 COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,1RNRX@1236|Gammaproteobacteria,464V1@72275|Alteromonadaceae 1236|Gammaproteobacteria P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) ppk GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006082,GO:0006091,GO:0006139,GO:0006163,GO:0006165,GO:0006464,GO:0006468,GO:0006725,GO:0006753,GO:0006757,GO:0006793,GO:0006796,GO:0006797,GO:0006799,GO:0006807,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009117,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009179,GO:0009185,GO:0009199,GO:0009205,GO:0009259,GO:0009279,GO:0009358,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016778,GO:0017144,GO:0019538,GO:0019637,GO:0019693,GO:0019867,GO:0030312,GO:0030313,GO:0031241,GO:0031975,GO:0032991,GO:0034641,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0043751,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044425,GO:0044462,GO:0044464,GO:0046031,GO:0046034,GO:0046483,GO:0046777,GO:0046939,GO:0055086,GO:0061695,GO:0071704,GO:0071944,GO:0072521,GO:0098552,GO:1901135,GO:1901360,GO:1901564,GO:1901576,GO:1902494,GO:1990234 2.7.4.1 ko:K00937 ko00190,ko03018,map00190,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - iSbBS512_1146.SbBS512_E2875 PP_kinase,PP_kinase_C,PP_kinase_N k141_20978_1 1279017.AQYJ01000024_gene1130 3.1e-114 340.0 COG3303@1|root,COG3303@2|Bacteria,1R5JF@1224|Proteobacteria,1S13K@1236|Gammaproteobacteria,4667Z@72275|Alteromonadaceae 1236|Gammaproteobacteria P Cytochrome c3 - - - - - - - - - - - - Cytochrom_C552,Cytochrom_c3_2 k141_20978_2 1279017.AQYJ01000024_gene1131 0.0 949.0 COG1251@1|root,COG1251@2|Bacteria,1MW58@1224|Proteobacteria,1RNGY@1236|Gammaproteobacteria,465T8@72275|Alteromonadaceae 1236|Gammaproteobacteria C Pyridine nucleotide-disulphide oxidoreductase - - 1.7.1.15 ko:K00362 ko00910,ko01120,map00910,map01120 M00530 R00787 RC00176 ko00000,ko00001,ko00002,ko01000 - - - Fer2_BFD,Pyr_redox_2 k141_20978_3 1453501.JELR01000002_gene99 2.93e-67 209.0 2BGQ8@1|root,32AP7@2|Bacteria,1RHYY@1224|Proteobacteria,1S82X@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Hemerythrin HHE cation binding domain - - - - - - - - - - - - Hemerythrin k141_36402_1 1249627.D779_4056 1.05e-72 229.0 COG5361@1|root,COG5361@2|Bacteria,1NZZJ@1224|Proteobacteria,1RSI3@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF1254) - - - - - - - - - - - - DUF1214,DUF1254 k141_31546_3 523791.Kkor_2048 1.35e-243 672.0 COG1062@1|root,COG1062@2|Bacteria,1MUK4@1224|Proteobacteria,1RNQ4@1236|Gammaproteobacteria,1XH2U@135619|Oceanospirillales 135619|Oceanospirillales C Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily adhC - 1.1.1.1,1.1.1.284 ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 - R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N k141_31546_4 1279017.AQYJ01000028_gene2428 6.76e-79 246.0 COG2207@1|root,COG2207@2|Bacteria,1MX23@1224|Proteobacteria,1RRXM@1236|Gammaproteobacteria 1236|Gammaproteobacteria K AraC family transcriptional regulator - - - - - - - - - - - - Arabinose_bd,HTH_18 k141_5769_1 218284.CCDN010000002_gene2417 3.34e-74 225.0 COG1670@1|root,COG1670@2|Bacteria,1V2C6@1239|Firmicutes,4HG3C@91061|Bacilli 91061|Bacilli J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins - - - - - - - - - - - - Acetyltransf_3 k141_5769_2 218284.CCDN010000001_gene462 8.41e-18 79.7 COG0588@1|root,COG0588@2|Bacteria,1TQFP@1239|Firmicutes,4HAW7@91061|Bacilli,1ZE2V@1386|Bacillus 91061|Bacilli G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate gpmA GO:0001871,GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009986,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030246,GO:0030247,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031,GO:2001065 5.4.2.11 ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - His_Phos_1 k141_37619_1 218284.CCDN010000005_gene3369 7.61e-102 299.0 COG0640@1|root,COG3860@1|root,COG0640@2|Bacteria,COG3860@2|Bacteria,1V1C5@1239|Firmicutes,4HG15@91061|Bacilli,1ZEHF@1386|Bacillus 91061|Bacilli K Uncharacterized protein conserved in bacteria (DUF2087) - - - - - - - - - - - - DUF2087,HTH_20,HTH_5 k141_28035_1 935836.JAEL01000017_gene774 2.38e-105 317.0 COG1292@1|root,COG1292@2|Bacteria,1TRS6@1239|Firmicutes,4HA7U@91061|Bacilli,1ZBRN@1386|Bacillus 91061|Bacilli M Belongs to the BCCT transporter (TC 2.A.15) family - - - ko:K05020 - - - - ko00000,ko02000 2.A.15.1.1,2.A.15.1.11 - - BCCT k141_29405_1 218284.CCDN010000004_gene3063 9.9e-133 381.0 COG1597@1|root,COG1597@2|Bacteria,1TRGQ@1239|Firmicutes,4HDR5@91061|Bacilli,1ZCT6@1386|Bacillus 91061|Bacilli I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase bmrU - - - - - - - - - - - DAGK_cat k141_1065_1 1385515.N791_02545 8.91e-81 254.0 COG2234@1|root,COG2234@2|Bacteria,1MWBX@1224|Proteobacteria,1RYHQ@1236|Gammaproteobacteria,1X2XJ@135614|Xanthomonadales 135614|Xanthomonadales S Peptidase m28 - - - - - - - - - - - - Peptidase_M28 k141_3229_1 471223.GWCH70_2861 2.55e-19 85.9 COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,4HA13@91061|Bacilli,1WEUE@129337|Geobacillus 91061|Bacilli E Beta-eliminating lyase yugH - - ko:K10907 - - - - ko00000,ko01000,ko01007 - - - Aminotran_1_2 k141_4430_2 218284.CCDN010000007_gene3877 4.19e-105 308.0 2C8AD@1|root,32RKP@2|Bacteria,1V1BI@1239|Firmicutes,4HFCW@91061|Bacilli,1ZE3F@1386|Bacillus 91061|Bacilli S Gas vesicle synthesis protein GvpL/GvpF - - - - - - - - - - - - GvpL_GvpF k141_5804_1 981383.AEWH01000071_gene1047 7.85e-62 193.0 COG2318@1|root,COG2318@2|Bacteria,1VC1G@1239|Firmicutes,4HMPJ@91061|Bacilli 91061|Bacilli S DinB superfamily - - - - - - - - - - - - DinB_2 k141_23778_1 1279017.AQYJ01000026_gene375 9.83e-192 546.0 COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,1RNAZ@1236|Gammaproteobacteria,464M5@72275|Alteromonadaceae 1236|Gammaproteobacteria L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseA GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494 3.1.11.6 ko:K03601 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_L,tRNA_anti_2 k141_23778_2 1453501.JELR01000001_gene1891 5.25e-227 665.0 COG0834@1|root,COG4623@1|root,COG0834@2|Bacteria,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,1RM8W@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella - GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - ko:K18691 - - - - ko00000,ko01000,ko01011 - - - SBP_bac_3,SLT k141_23778_3 1453501.JELR01000002_gene772 1.68e-273 780.0 COG0834@1|root,COG4623@1|root,COG0834@2|Bacteria,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,1RM8W@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella - GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - ko:K18691 - - - - ko00000,ko01000,ko01011 - - - SBP_bac_3,SLT k141_23778_4 1042377.AFPJ01000037_gene2946 0.0 1182.0 COG1629@1|root,COG4771@2|Bacteria,1QYDM@1224|Proteobacteria,1RYCH@1236|Gammaproteobacteria,469WZ@72275|Alteromonadaceae 1236|Gammaproteobacteria P TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_23778_5 1123368.AUIS01000019_gene1220 3.22e-36 125.0 COG0662@1|root,COG0662@2|Bacteria,1N7Q4@1224|Proteobacteria,1SEVR@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Cupin domain - - - - - - - - - - - - Cupin_2 k141_23778_6 1042377.AFPJ01000037_gene2947 3.02e-101 298.0 COG0259@1|root,COG0259@2|Bacteria,1NZUU@1224|Proteobacteria,1RMQ2@1236|Gammaproteobacteria,466CT@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) pdxH GO:0000166,GO:0003674,GO:0003824,GO:0004733,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009108,GO:0009110,GO:0009443,GO:0009987,GO:0010181,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019842,GO:0032553,GO:0032991,GO:0034641,GO:0036094,GO:0042301,GO:0042364,GO:0042802,GO:0042803,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0043094,GO:0043167,GO:0043168,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902444 1.4.3.5 ko:K00275 ko00750,ko01100,ko01120,map00750,map01100,map01120 M00124 R00277,R00278,R01710,R01711 RC00048,RC00116 ko00000,ko00001,ko00002,ko01000 - - - PNP_phzG_C,Putative_PNPOx k141_23778_7 1279017.AQYJ01000021_gene2944 2.72e-192 546.0 COG0028@1|root,COG0028@2|Bacteria,1MWVW@1224|Proteobacteria,1RPZ2@1236|Gammaproteobacteria,465G8@72275|Alteromonadaceae 1236|Gammaproteobacteria EH Thiamine pyrophosphate enzyme, central domain - - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N k141_32964_1 218284.CCDN010000006_gene3517 9.81e-47 163.0 COG3263@1|root,COG3263@2|Bacteria,1TQPJ@1239|Firmicutes,4HC8I@91061|Bacilli,1ZC6H@1386|Bacillus 91061|Bacilli P COG3263 NhaP-type Na H and K H antiporters with a unique C-terminal domain cvrA - - ko:K11105 - - - - ko00000,ko02000 2.A.36.6 - - Na_H_Exchanger,TrkA_C k141_29443_1 1473546.CH76_13115 3.42e-29 119.0 COG1982@1|root,COG1982@2|Bacteria,1TNZ9@1239|Firmicutes,4HBGC@91061|Bacilli,3IVWC@400634|Lysinibacillus 91061|Bacilli E Lysine decarboxylase yaaO - - - - - - - - - - - OKR_DC_1,OKR_DC_1_C k141_5805_1 1294265.JCM21738_4416 2.98e-70 216.0 COG0274@1|root,COG0274@2|Bacteria,1TPAJ@1239|Firmicutes,4HAAJ@91061|Bacilli,1ZCZ6@1386|Bacillus 91061|Bacilli F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate deoC GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4 ko:K01619 ko00030,map00030 - R01066 RC00436,RC00437 ko00000,ko00001,ko01000 - - iYO844.BSU39420 DeoC k141_20998_4 1121015.N789_06585 1.52e-27 110.0 COG1566@1|root,COG1566@2|Bacteria,1RJ3I@1224|Proteobacteria,1S7BS@1236|Gammaproteobacteria,1X4Y6@135614|Xanthomonadales 135614|Xanthomonadales V Protein of unknown function (DUF3667) - - - - - - - - - - - - DUF3667 k141_31573_1 1294265.JCM21738_3607 2.4e-65 201.0 COG3543@1|root,COG3543@2|Bacteria,1VFVM@1239|Firmicutes,4HIWH@91061|Bacilli,1ZFNV@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF1284) - - - ko:K09706 - - - - ko00000 - - - DUF1284 k141_31573_2 1294265.JCM21738_3608 8.77e-35 124.0 COG0569@1|root,COG0569@2|Bacteria,1V80K@1239|Firmicutes,4HQC5@91061|Bacilli,1ZE53@1386|Bacillus 91061|Bacilli P PFAM TrkA-C domain protein - - - - - - - - - - - - TrkA_C k141_23779_1 671143.DAMO_1215 3.73e-46 158.0 COG0524@1|root,COG0524@2|Bacteria,2NP1T@2323|unclassified Bacteria 2|Bacteria G pfkB family carbohydrate kinase adoK GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004001,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005975,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019200,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032552,GO:0032553,GO:0032554,GO:0032555,GO:0032559,GO:0032560,GO:0032561,GO:0032567,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046390,GO:0046483,GO:0046835,GO:0046872,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.15,2.7.1.20 ko:K00852,ko:K00856 ko00030,ko00230,ko01100,map00030,map00230,map01100 - R00185,R01051,R02750 RC00002,RC00017 ko00000,ko00001,ko01000 - - iAF987.Gmet_2683 PfkB k141_3249_1 1219076.N646_4048 5.15e-98 289.0 COG1024@1|root,COG1024@2|Bacteria,1MVEC@1224|Proteobacteria,1RP85@1236|Gammaproteobacteria,1XT8I@135623|Vibrionales 135623|Vibrionales I COG1024 Enoyl-CoA hydratase carnithine racemase - - 4.2.1.18 ko:K13766 ko00280,ko01100,map00280,map01100 M00036 R02085 RC02416 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 k141_3249_2 1116375.VEJY3_18536 2.95e-190 539.0 COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,1RNV5@1236|Gammaproteobacteria,1XU22@135623|Vibrionales 135623|Vibrionales I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) - - 6.4.1.4 ko:K01969 ko00280,ko01100,map00280,map01100 M00036 R04138 RC00367,RC00942 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans k141_34245_1 1348635.BBJY01000001_gene2372 1.67e-163 468.0 COG1063@1|root,COG1063@2|Bacteria,1MV9A@1224|Proteobacteria,1RWRJ@1236|Gammaproteobacteria,1XWEE@135623|Vibrionales 135623|Vibrionales E Alcohol dehydrogenase GroES-like domain - - - - - - - - - - - - ADH_N,ADH_zinc_N k141_34245_2 94122.Shewana3_0304 9.29e-73 223.0 COG1917@1|root,COG1917@2|Bacteria,1N0BS@1224|Proteobacteria,1SBE0@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Cupin 2, conserved barrel domain protein - - - - - - - - - - - - Cupin_7 k141_35532_1 1279017.AQYJ01000026_gene65 1.33e-131 404.0 COG4105@1|root,COG4105@2|Bacteria,1QVQ9@1224|Proteobacteria,1RSIG@1236|Gammaproteobacteria,46DC5@72275|Alteromonadaceae 1236|Gammaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16,TPR_6 k141_12977_1 1117318.PRUB_21028 3.6e-15 73.2 COG4764@1|root,COG4764@2|Bacteria,1MVRK@1224|Proteobacteria,1RQ79@1236|Gammaproteobacteria,2Q10Q@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - SLT k141_12977_2 1042377.AFPJ01000053_gene1492 4.27e-131 375.0 COG0120@1|root,COG0120@2|Bacteria,1MVGR@1224|Proteobacteria,1RNF8@1236|Gammaproteobacteria,46422@72275|Alteromonadaceae 1236|Gammaproteobacteria G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate rpiA - 5.3.1.6 ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167,M00580 R01056 RC00434 ko00000,ko00001,ko00002,ko01000 - - - Rib_5-P_isom_A k141_32966_1 926550.CLDAP_24790 4.06e-10 60.5 COG1070@1|root,COG1070@2|Bacteria 2|Bacteria G xylulokinase activity - - 2.7.1.12,2.7.1.17,2.7.1.215,2.7.1.5 ko:K00848,ko:K00851,ko:K00854,ko:K00862 ko00030,ko00040,ko00051,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00040,map00051,map01100,map01110,map01120,map01130,map01200 M00014 R01639,R01737,R01902,R03014,R11536 RC00002,RC00017,RC00538 ko00000,ko00001,ko00002,ko01000 - - - FGGY_C,FGGY_N k141_37643_1 218284.CCDN010000001_gene1735 2e-143 422.0 COG1368@1|root,COG1368@2|Bacteria,1TRMA@1239|Firmicutes,4HFA5@91061|Bacilli,1ZDG2@1386|Bacillus 91061|Bacilli M Sulfatase - - - - - - - - - - - - Sulfatase k141_4433_1 1408424.JHYI01000018_gene3125 4.31e-118 347.0 COG0524@1|root,COG0524@2|Bacteria,1TPGM@1239|Firmicutes,4HD0H@91061|Bacilli,1ZASN@1386|Bacillus 91061|Bacilli G Belongs to the carbohydrate kinase PfkB family - - 2.7.1.4 ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 - R00760,R00867,R03920 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB k141_35533_1 218284.CCDN010000001_gene976 2.23e-128 368.0 COG0745@1|root,COG0745@2|Bacteria,1TPF7@1239|Firmicutes,4HA1M@91061|Bacilli,1ZBNB@1386|Bacillus 91061|Bacilli KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process spo0A GO:0000003,GO:0000156,GO:0000160,GO:0000910,GO:0003674,GO:0006355,GO:0007049,GO:0007154,GO:0007165,GO:0008150,GO:0008356,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016043,GO:0019219,GO:0019222,GO:0019954,GO:0022402,GO:0022603,GO:0022607,GO:0023052,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0032506,GO:0035556,GO:0042173,GO:0042710,GO:0043934,GO:0043937,GO:0043938,GO:0044010,GO:0044085,GO:0044764,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051171,GO:0051252,GO:0051301,GO:0051704,GO:0051716,GO:0060089,GO:0060255,GO:0065007,GO:0071840,GO:0080090,GO:0090529,GO:0090604,GO:0090606,GO:1903506,GO:2000112,GO:2001141 - ko:K07699 ko02020,ko02024,map02020,map02024 M00485 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Spo0A_C k141_1984_1 1294265.JCM21738_2684 6.01e-98 293.0 COG2311@1|root,COG2311@2|Bacteria,1TQNS@1239|Firmicutes,4HCR3@91061|Bacilli,1ZBX3@1386|Bacillus 91061|Bacilli P Protein of unknown function (DUF418) - - - ko:K07148 - - - - ko00000 - - - DUF418 k141_29444_2 218284.CCDN010000008_gene4189 3.75e-130 384.0 COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,4H9RY@91061|Bacilli,1ZBR9@1386|Bacillus 91061|Bacilli S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid ytgP GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03328 - - - - ko00000 2.A.66.2 - - Polysacc_synt,Polysacc_synt_C k141_17697_1 223926.28807839 4.27e-281 773.0 COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,1RMJE@1236|Gammaproteobacteria,1XTMH@135623|Vibrionales 135623|Vibrionales G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate gpmI GO:0003674,GO:0003824,GO:0004619,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.4.2.12 ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000 - - - Metalloenzyme,Phosphodiest,iPGM_N k141_17697_2 1116375.VEJY3_14405 5.03e-141 402.0 COG0697@1|root,COG0697@2|Bacteria,1R4G2@1224|Proteobacteria,1S1NT@1236|Gammaproteobacteria,1XTQV@135623|Vibrionales 135623|Vibrionales EG of the drug metabolite transporter (DMT) superfamily - - - - - - - - - - - - EamA k141_37815_1 218284.CCDN010000001_gene1479 2.77e-20 87.4 COG1648@1|root,COG1648@2|Bacteria,1VA2E@1239|Firmicutes,4HIRG@91061|Bacilli,1ZHMG@1386|Bacillus 91061|Bacilli H Siroheme synthase sirC - 1.3.1.76,4.99.1.4 ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02864,R03947 RC01012,RC01034 ko00000,ko00001,ko00002,ko01000 - - - NAD_binding_7,Sirohm_synth_M k141_15230_1 768066.HELO_1680 4.45e-127 371.0 COG0673@1|root,COG0673@2|Bacteria,1MU8F@1224|Proteobacteria,1RNKY@1236|Gammaproteobacteria,1XI61@135619|Oceanospirillales 135619|Oceanospirillales S oxidoreductase - - 1.1.1.371 ko:K16044 ko00562,ko01120,map00562,map01120 - R09954 RC00182 ko00000,ko00001,ko01000 - - - GFO_IDH_MocA,GFO_IDH_MocA_C k141_30519_1 1116375.VEJY3_04895 1.7e-280 773.0 COG1271@1|root,COG1271@2|Bacteria,1MV60@1224|Proteobacteria,1RN2U@1236|Gammaproteobacteria,1XT5F@135623|Vibrionales 135623|Vibrionales C COG1271 Cytochrome bd-type quinol oxidase, subunit 1 cydA - 1.10.3.14 ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - Cyt_bd_oxida_I k141_30519_2 223926.28806041 2.36e-268 735.0 COG1294@1|root,COG1294@2|Bacteria,1MURP@1224|Proteobacteria,1RP7F@1236|Gammaproteobacteria,1XVFM@135623|Vibrionales 135623|Vibrionales C COG1294 Cytochrome bd-type quinol oxidase, subunit 2 cydB - 1.10.3.14 ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - Cyt_bd_oxida_II k141_30519_3 945550.VISI1226_13281 2.65e-18 75.5 COG4890@1|root,COG4890@2|Bacteria,1NGDQ@1224|Proteobacteria,1SGGW@1236|Gammaproteobacteria,1XZED@135623|Vibrionales 135623|Vibrionales S Outer membrane lipoprotein - - 1.10.3.14 ko:K00424 ko00190,ko02020,map00190,map02020 M00153 - - ko00000,ko00001,ko01000 3.D.4.3 - - YbgT_YccB k141_30519_4 223926.28806042 3.31e-65 198.0 COG3790@1|root,COG3790@2|Bacteria,1MZDH@1224|Proteobacteria,1SA3Q@1236|Gammaproteobacteria,1XXY3@135623|Vibrionales 135623|Vibrionales S Cyd operon protein YbgE - - - - - - - - - - - - Cyd_oper_YbgE k141_30519_5 1116375.VEJY3_04915 6.98e-82 243.0 COG0824@1|root,COG0824@2|Bacteria,1MZH6@1224|Proteobacteria,1S93F@1236|Gammaproteobacteria,1XXKJ@135623|Vibrionales 135623|Vibrionales S Thioesterase-like superfamily ybgC - - ko:K07107 - - - - ko00000,ko01000 - - - 4HBT k141_30519_6 1116375.VEJY3_04920 1.08e-152 430.0 COG0811@1|root,COG0811@2|Bacteria,1NCWW@1224|Proteobacteria,1RMD4@1236|Gammaproteobacteria,1XUNH@135623|Vibrionales 135623|Vibrionales U COG0811 Biopolymer transport proteins tolQ - - ko:K03562 ko01120,map01120 - - - ko00000,ko02000 1.A.30.2.2 - - MotA_ExbB k141_30519_7 1116375.VEJY3_04925 1.94e-93 273.0 COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,1S8RS@1236|Gammaproteobacteria,1XWZR@135623|Vibrionales 135623|Vibrionales U TolR membrane protein tolR - - ko:K03560 - - - - ko00000,ko02000 1.A.30.2.2 - - ExbD k141_30519_8 223926.28806046 1.99e-87 274.0 COG3064@1|root,COG3064@2|Bacteria,1MVQS@1224|Proteobacteria,1RP2V@1236|Gammaproteobacteria,1XSTI@135623|Vibrionales 135623|Vibrionales M COG3064 Membrane protein involved in colicin uptake tolA - - ko:K03646 - - - - ko00000,ko02000 2.C.1.2 - - TolA k141_30519_9 223926.28806047 1.86e-218 615.0 COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,1RMCY@1236|Gammaproteobacteria,1XSZN@135623|Vibrionales 135623|Vibrionales U Involved in the TonB-independent uptake of proteins tolB GO:0003674,GO:0005215 - ko:K03641 - - - - ko00000,ko02000 2.C.1.2 - - PD40,TolB_N k141_31664_1 1279017.AQYJ01000029_gene3461 2.65e-82 257.0 COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,1RNN9@1236|Gammaproteobacteria,464N3@72275|Alteromonadaceae 1236|Gammaproteobacteria OU COG0616 Periplasmic serine proteases (ClpP class) sohB GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0016020,GO:0019538,GO:0043170,GO:0044238,GO:0044464,GO:0071704,GO:0071944,GO:1901564 - ko:K04774 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S49,Peptidase_S49_N k141_31664_2 1042377.AFPJ01000031_gene575 8.06e-115 333.0 290UJ@1|root,2ZNGJ@2|Bacteria,1RBSP@1224|Proteobacteria,1S3RZ@1236|Gammaproteobacteria,4675M@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_31664_3 1042377.AFPJ01000031_gene574 8.27e-66 208.0 COG2816@1|root,COG2816@2|Bacteria,1QGCX@1224|Proteobacteria,1RP0Y@1236|Gammaproteobacteria,466XD@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding nudC GO:0003674,GO:0003824,GO:0004551,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030145,GO:0033554,GO:0034641,GO:0035529,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.6.1.22 ko:K03426 ko00760,ko01100,ko04146,map00760,map01100,map04146 - R00103,R03004,R11104 RC00002 ko00000,ko00001,ko01000 - - iAF1260.b3996,iB21_1397.B21_03826,iBWG_1329.BWG_3656,iEC55989_1330.EC55989_4481,iECBD_1354.ECBD_4036,iECB_1328.ECB_03873,iECDH10B_1368.ECDH10B_4185,iECDH1ME8569_1439.ECDH1ME8569_3856,iECD_1391.ECD_03873,iECIAI1_1343.ECIAI1_4211,iECO103_1326.ECO103_4745,iECO111_1330.ECO111_4813,iECO26_1355.ECO26_5105,iECSE_1348.ECSE_4284,iECW_1372.ECW_m4355,iEKO11_1354.EKO11_4325,iETEC_1333.ETEC_4256,iEcDH1_1363.EcDH1_3998,iEcE24377_1341.EcE24377A_4539,iEcHS_1320.EcHS_A4230,iEcolC_1368.EcolC_4029,iJO1366.b3996,iPC815.YPO3736,iSSON_1240.SSON_4169,iUMNK88_1353.UMNK88_4837,iWFL_1372.ECW_m4355,iY75_1357.Y75_RS17065,iYL1228.KPN_04378 NUDIX,NUDIX-like,zf-NADH-PPase k141_8042_1 265729.GS18_0206730 6.2e-28 104.0 COG4876@1|root,COG4876@2|Bacteria,1VNEJ@1239|Firmicutes,4HR86@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - DUF2188 k141_8042_2 218284.CCDN010000005_gene3440 9.31e-74 222.0 COG2050@1|root,COG2050@2|Bacteria,1V7G2@1239|Firmicutes,4HIIA@91061|Bacilli,1ZGY5@1386|Bacillus 91061|Bacilli Q protein, possibly involved in aromatic compounds catabolism yuxO - - - - - - - - - - - 4HBT k141_34385_1 203122.Sde_2501 1.02e-139 413.0 COG1874@1|root,COG1874@2|Bacteria,1P0Y5@1224|Proteobacteria,1RZHZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Glycoside Hydrolase - - - - - - - - - - - - Glyco_hydro_35,Glyco_hydro_42 k141_17699_1 315749.Bcer98_0029 2.81e-76 234.0 COG4123@1|root,COG4123@2|Bacteria,1TQ25@1239|Firmicutes,4HA8W@91061|Bacilli,1ZCBX@1386|Bacillus 91061|Bacilli S Conserved hypothetical protein 95 yabB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.223 ko:K07461,ko:K15460 - - - - ko00000,ko01000,ko03016 - - - GIY-YIG,MTS k141_37817_1 218284.CCDN010000006_gene3642 3.97e-62 205.0 COG0141@1|root,COG0141@2|Bacteria,1TPAW@1239|Firmicutes,4H9XK@91061|Bacilli,1ZCAX@1386|Bacillus 91061|Bacilli E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine hisD GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01158,R01163,R03012 RC00099,RC00242,RC00463 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU34910 Histidinol_dh k141_36512_1 1340434.AXVA01000005_gene4757 1.5e-20 89.0 COG1702@1|root,COG1702@2|Bacteria,1TP35@1239|Firmicutes,4HBD5@91061|Bacilli,1ZBVE@1386|Bacillus 91061|Bacilli T Phosphate starvation-inducible protein PhoH phoH - - ko:K06217 - - - - ko00000 - - - PhoH k141_15231_1 218284.CCDN010000001_gene1385 4.13e-154 442.0 COG0014@1|root,COG0014@2|Bacteria,1TQ9V@1239|Firmicutes,4HB7B@91061|Bacilli,1ZC00@1386|Bacillus 91061|Bacilli E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate proA - 1.2.1.41 ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 M00015 R03313 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_3405_1 1116375.VEJY3_11130 9.58e-131 388.0 COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,1RNYW@1236|Gammaproteobacteria,1XT9K@135623|Vibrionales 135623|Vibrionales OU signal peptide peptidase sppA - - ko:K04773 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S49 k141_3405_2 1280001.BAOA01000008_gene4080 2.12e-101 301.0 COG0252@1|root,COG0252@2|Bacteria,1MWIR@1224|Proteobacteria,1RMUB@1236|Gammaproteobacteria,1XU6G@135623|Vibrionales 135623|Vibrionales EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D ansA - 3.5.1.1 ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 - R00485 RC00010,RC02798 ko00000,ko00001,ko01000 - - - Asparaginase k141_29672_3 700598.Niako_4002 4.34e-05 52.4 COG1266@1|root,COG1266@2|Bacteria,4NSYU@976|Bacteroidetes,1IX2X@117747|Sphingobacteriia 976|Bacteroidetes S PFAM Abortive infection protein - - - ko:K07052 - - - - ko00000 - - - Abi k141_37818_1 1347369.CCAD010000091_gene2130 7.26e-65 215.0 COG3852@1|root,COG3852@2|Bacteria,1TRH0@1239|Firmicutes,4HD4A@91061|Bacilli,1ZARI@1386|Bacillus 91061|Bacilli T COG0642 Signal transduction histidine kinase - - 2.7.13.3 ko:K02491,ko:K07698 ko02020,map02020 M00485 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS,PAS_3,PAS_9 k141_34387_1 218284.CCDN010000001_gene637 6.87e-105 313.0 COG0536@1|root,COG0536@2|Bacteria,1TPX7@1239|Firmicutes,4H9P8@91061|Bacilli,1ZCM4@1386|Bacillus 91061|Bacilli S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control obg GO:0000003,GO:0000160,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0017076,GO:0019001,GO:0019954,GO:0023052,GO:0030436,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035556,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043934,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03979 - - - - ko00000,ko01000,ko03009 - - - DUF1967,GTP1_OBG,MMR_HSR1 k141_28227_1 1116375.VEJY3_02890 6.53e-112 324.0 COG0586@1|root,COG0586@2|Bacteria,1MX4M@1224|Proteobacteria,1RPB1@1236|Gammaproteobacteria,1XVK2@135623|Vibrionales 135623|Vibrionales S membrane-associated protein VV0785 - - - - - - - - - - - SNARE_assoc k141_28227_2 1116375.VEJY3_02895 0.0 1009.0 COG0388@1|root,COG0388@2|Bacteria,1MX4I@1224|Proteobacteria,1RP30@1236|Gammaproteobacteria,1XUX9@135623|Vibrionales 135623|Vibrionales S Carbon-nitrogen hydrolase - - - - - - - - - - - - Acetyltransf_1,CN_hydrolase k141_28227_3 1116375.VEJY3_02900 4.4e-177 497.0 COG0583@1|root,COG0583@2|Bacteria,1RABJ@1224|Proteobacteria,1S2NH@1236|Gammaproteobacteria,1XVYJ@135623|Vibrionales 135623|Vibrionales K Bacterial regulatory helix-turn-helix protein, lysR family - - - - - - - - - - - - HTH_1,LysR_substrate k141_28227_4 1316927.ATKI01000047_gene614 1.05e-44 148.0 COG0745@1|root,COG0745@2|Bacteria,1RHDD@1224|Proteobacteria,1S67R@1236|Gammaproteobacteria,1YTK0@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria KT Protein involved in kinase activity, two-component response regulator activity, chemotaxis, two-component signal transduction system (phosphorelay) and regulation of transcription, DNA-dependent IV02_18015 - - ko:K03413 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - Response_reg k141_28227_6 998088.B565_3177 4.82e-165 498.0 COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1Y5C5@135624|Aeromonadales 135624|Aeromonadales NT Signal transducing histidine kinase, homodimeric domain - - 2.7.13.3 ko:K03407 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt k141_28227_7 318161.Sden_3298 4.76e-43 148.0 COG0835@1|root,COG0835@2|Bacteria,1RAH1@1224|Proteobacteria,1RXU3@1236|Gammaproteobacteria,2QE0Q@267890|Shewanellaceae 1236|Gammaproteobacteria NT Two component signalling adaptor domain - - - ko:K03408 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - CheW k141_28227_8 1124991.MU9_702 1.64e-27 124.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria 1224|Proteobacteria NT chemotaxis, protein - - - ko:K05874 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - 4HB_MCP_1,MCPsignal k141_28227_9 1316927.ATKI01000047_gene619 1.17e-64 210.0 COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,1RMFK@1236|Gammaproteobacteria,1YSX9@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria H Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP cheR2 - 2.1.1.80 ko:K00575 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko01000,ko02035 - - - CheR,CheR_N k141_28227_10 1415630.U771_22250 9.56e-131 385.0 COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,1RN67@1236|Gammaproteobacteria 1236|Gammaproteobacteria NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR cheB1 - 3.1.1.61,3.5.1.44 ko:K03412 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 - - - CheB_methylest,Response_reg k141_28227_11 1123487.KB892834_gene2829 3.52e-37 151.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2WIC6@28216|Betaproteobacteria,2KZQS@206389|Rhodocyclales 1224|Proteobacteria T Domain of unknown function (DUF3369) - - - - - - - - - - - - CHASE2,DUF3369,EAL,GGDEF,HAMP,PAS,PAS_3,PAS_8,Response_reg k141_28227_12 1116375.VEJY3_02935 0.0 1030.0 COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria,1XTS1@135623|Vibrionales 1236|Gammaproteobacteria O COG1404 Subtilisin-like serine proteases - - - - - - - - - - - - PA,PKD,Peptidase_S8 k141_28227_13 1116375.VEJY3_02940 0.0 1514.0 2EXJW@1|root,33QVY@2|Bacteria,1QSMJ@1224|Proteobacteria,1SK5H@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_28227_14 1116375.VEJY3_02945 3.06e-104 304.0 2BN4A@1|root,32GR8@2|Bacteria,1RHQ4@1224|Proteobacteria,1S86P@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_31666_1 861299.J421_1661 7.3e-33 127.0 COG0534@1|root,COG0534@2|Bacteria,1ZUGI@142182|Gemmatimonadetes 142182|Gemmatimonadetes V MatE - - - - - - - - - - - - MatE k141_17700_1 37105.F8J1G5_9CAUD 6.61e-17 75.9 4QFZA@10239|Viruses,4QX9P@35237|dsDNA viruses no RNA stage,4QTE4@28883|Caudovirales,4QMNQ@10699|Siphoviridae 10699|Siphoviridae S Domain of Unknown Function (DUF1599) - - - - - - - - - - - - - k141_17700_3 1295642.H839_08129 8.3e-26 97.1 COG3655@1|root,COG3655@2|Bacteria 2|Bacteria K Transcriptional regulator - - - ko:K07727 - - - - ko00000,ko03000 - - - HTH_26,HTH_3 k141_29673_1 1294265.JCM21738_5203 1.62e-115 342.0 COG0477@1|root,COG2814@2|Bacteria,1TS1D@1239|Firmicutes,4HCUB@91061|Bacilli,1ZBCP@1386|Bacillus 91061|Bacilli EGP MFS_1 like family - - - - - - - - - - - - MFS_1,MFS_1_like k141_15232_1 218284.CCDN010000001_gene53 8.05e-20 87.4 COG1293@1|root,COG1293@2|Bacteria,1TQ8A@1239|Firmicutes,4H9UF@91061|Bacilli,1ZBGD@1386|Bacillus 91061|Bacilli K RNA-binding protein homologous to eukaryotic snRNP FbpA - - - - - - - - - - - DUF814,FbpA k141_15232_2 218284.CCDN010000001_gene52 7.96e-40 146.0 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4H9S5@91061|Bacilli,1ZCDJ@1386|Bacillus 91061|Bacilli P COG0474 Cation transport ATPase yloB GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - iYO844.BSU15650 Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase k141_3406_1 926550.CLDAP_27990 1.31e-64 210.0 COG0183@1|root,COG0183@2|Bacteria,2G63J@200795|Chloroflexi 200795|Chloroflexi I Belongs to the thiolase family - - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N k141_37819_1 1279017.AQYJ01000024_gene905 6.49e-128 392.0 COG2374@1|root,COG3291@1|root,COG2374@2|Bacteria,COG3291@2|Bacteria,1MX52@1224|Proteobacteria,1RMHH@1236|Gammaproteobacteria,46500@72275|Alteromonadaceae 1236|Gammaproteobacteria L Extracellular nuclease - - - ko:K07004 - - - - ko00000 - - - Endonuclease_1,Exo_endo_phos,LTD k141_31667_1 1453501.JELR01000001_gene2206 2.28e-93 285.0 COG1167@1|root,COG1167@2|Bacteria,1MV6F@1224|Proteobacteria,1RMQ0@1236|Gammaproteobacteria,465KT@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs - - - - - - - - - - - - Aminotran_1_2,GntR k141_8045_1 1042377.AFPJ01000020_gene2053 7.19e-72 229.0 COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,1RN14@1236|Gammaproteobacteria,465VG@72275|Alteromonadaceae 1236|Gammaproteobacteria D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine tilS GO:0002097,GO:0002101,GO:0002136,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016879,GO:0032267,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 6.3.4.19 ko:K04075 - - R09597 RC02633,RC02634 ko00000,ko01000,ko03016 - - - ATP_bind_3,TilS,TilS_C k141_36513_1 1117647.M5M_16815 4.47e-167 499.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MWS3@1224|Proteobacteria,1RPG6@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Outer membrane receptor proteins mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec k141_10626_2 218284.CCDN010000001_gene1116 1.46e-55 176.0 COG4401@1|root,COG4401@2|Bacteria,1VAID@1239|Firmicutes,4HKTN@91061|Bacilli,1ZH0S@1386|Bacillus 91061|Bacilli E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis aroH GO:0003674,GO:0003824,GO:0004106,GO:0006082,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044281,GO:0046417,GO:0071704 5.4.99.5 ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024,M00025 R01715 RC03116 ko00000,ko00001,ko00002,ko01000 - - - CM_1 k141_10626_3 218284.CCDN010000001_gene1117 6.94e-180 508.0 COG0079@1|root,COG0079@2|Bacteria,1TPUV@1239|Firmicutes,4HA1H@91061|Bacilli,1ZBYJ@1386|Bacillus 91061|Bacilli E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily hisC - 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k141_17702_1 218284.CCDN010000003_gene2992 8.75e-80 251.0 COG1694@1|root,COG3956@2|Bacteria,1TPK1@1239|Firmicutes,4HA0A@91061|Bacilli,1ZAYB@1386|Bacillus 91061|Bacilli S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like yabN GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.66 ko:K02428,ko:K02499 ko00230,map00230 - R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000,ko03036 - - - MazG,TP_methylase k141_29675_1 1294265.JCM21738_2596 4.83e-115 333.0 28NT3@1|root,2ZBRV@2|Bacteria,1V1C2@1239|Firmicutes,4HFYQ@91061|Bacilli,1ZFIE@1386|Bacillus 91061|Bacilli S YwiC-like protein - - - - - - - - - - - - YwiC k141_28228_1 223926.28810137 5.16e-237 666.0 COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1MUQV@1224|Proteobacteria,1RN0Q@1236|Gammaproteobacteria,1XU7X@135623|Vibrionales 135623|Vibrionales T COG2199 FOG GGDEF domain VVA1653 - - - - - - - - - - - EAL,GGDEF,HAMP,LapD_MoxY_N k141_34389_1 441769.ABFU01000057_gene808 1.22e-34 131.0 COG1033@1|root,COG1033@2|Bacteria,1VSWA@1239|Firmicutes,4HBIV@91061|Bacilli 91061|Bacilli S MMPL family ydfJ - - ko:K07003 - - - - ko00000 - - - MMPL k141_28281_5 223926.28808234 3.69e-74 226.0 COG3047@1|root,COG3047@2|Bacteria,1NUZJ@1224|Proteobacteria,1RRRC@1236|Gammaproteobacteria,1XSCD@135623|Vibrionales 135623|Vibrionales M Outer membrane protein W ompW GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - ko:K07275 - - - - ko00000 - - - OmpW k141_37867_1 1068978.AMETH_5298 7.93e-57 190.0 COG2072@1|root,COG2072@2|Bacteria,2GM3S@201174|Actinobacteria,4E20H@85010|Pseudonocardiales 201174|Actinobacteria P L-lysine 6-monooxygenase (NADPH-requiring) - - - ko:K07222 - - - - ko00000 - - - Pyr_redox_3 k141_36569_1 698769.JFBD01000060_gene996 1.9e-33 127.0 29H5Q@1|root,31K0D@2|Bacteria,1V2CP@1239|Firmicutes,4HGS2@91061|Bacilli 91061|Bacilli S Nuclease-related domain - - - - - - - - - - - - NERD k141_4639_2 218284.CCDN010000001_gene1003 1.26e-197 555.0 COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,4HADJ@91061|Bacilli,1ZAZZ@1386|Bacillus 91061|Bacilli L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII dinB GO:0008150,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0050896 2.7.7.7 ko:K02346 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH k141_16573_1 1294265.JCM21738_4272 4.54e-81 244.0 COG5482@1|root,COG5482@2|Bacteria,1V3FI@1239|Firmicutes,4HI6C@91061|Bacilli,1ZDPW@1386|Bacillus 91061|Bacilli S Putative PD-(D/E)XK phosphodiesterase (DUF2161) - - - - - - - - - - - - DUF2161 k141_15266_1 223926.28807760 1.97e-179 505.0 COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,1RN8S@1236|Gammaproteobacteria,1XTH1@135623|Vibrionales 135623|Vibrionales NU COG4972 Tfp pilus assembly protein, ATPase PilM pilM - - ko:K02662 - - - - ko00000,ko02035,ko02044 - - - PilM_2 k141_15266_2 1116375.VEJY3_14075 0.0 1477.0 COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,1RM7J@1236|Gammaproteobacteria,1XT2B@135623|Vibrionales 135623|Vibrionales M COG5009 Membrane carboxypeptidase penicillin-binding protein mrcA GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - PCB_OB,Transgly,Transpeptidase k141_15266_3 1116375.VEJY3_14080 7.15e-202 560.0 COG0583@1|root,COG0583@2|Bacteria,1MVA1@1224|Proteobacteria,1RPAJ@1236|Gammaproteobacteria,1XSJB@135623|Vibrionales 135623|Vibrionales K COG0583 Transcriptional regulator oxyR - - ko:K04761 ko02026,map02026 - - - ko00000,ko00001,ko03000 - - - HTH_1,LysR_substrate k141_15266_4 1116375.VEJY3_14085 1.27e-165 464.0 COG0678@1|root,COG0695@1|root,COG0678@2|Bacteria,COG0695@2|Bacteria,1MU0H@1224|Proteobacteria,1RRFB@1236|Gammaproteobacteria,1XSPT@135623|Vibrionales 135623|Vibrionales O Peroxiredoxin family protein glutaredoxin - - - - - - - - - - - - Glutaredoxin,Redoxin k141_15266_5 1116375.VEJY3_14090 0.0 1216.0 COG0165@1|root,COG1246@1|root,COG0165@2|Bacteria,COG1246@2|Bacteria,1MUTU@1224|Proteobacteria,1RMA3@1236|Gammaproteobacteria,1XSAT@135623|Vibrionales 135623|Vibrionales E belongs to the lyase 1 family. Argininosuccinate lyase subfamily argH GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,4.3.2.1 ko:K14681 ko00220,ko00250,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map01100,map01110,map01130,map01210,map01230 M00028,M00029,M00844 R00259,R01086 RC00004,RC00064,RC00445,RC00447 ko00000,ko00001,ko00002,ko01000 - - - ASL_C2,Acetyltransf_1,Lyase_1 k141_15266_6 223926.28807767 9.36e-295 804.0 COG0137@1|root,COG0137@2|Bacteria,1MV0Y@1224|Proteobacteria,1RMEC@1236|Gammaproteobacteria,1XU2D@135623|Vibrionales 135623|Vibrionales F Belongs to the argininosuccinate synthase family. Type 1 subfamily argG GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 M00029,M00844,M00845 R01954 RC00380,RC00629 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Arginosuc_synth k141_30559_1 573061.Clocel_3533 1.39e-21 96.3 COG5280@1|root,COG5412@1|root,COG5280@2|Bacteria,COG5412@2|Bacteria,1TQ28@1239|Firmicutes,247QT@186801|Clostridia,36E7F@31979|Clostridiaceae 186801|Clostridia M tail tape measure protein - - - - - - - - - - - - PhageMin_Tail k141_8078_1 1453501.JELR01000001_gene3168 5.13e-46 167.0 COG2304@1|root,COG2304@2|Bacteria,1MW8K@1224|Proteobacteria,1RNU3@1236|Gammaproteobacteria,46676@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein containing a von Willebrand factor type A (vWA) domain - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - VIT,VWA_3 k141_8078_4 1279017.AQYJ01000022_gene2680 1.09e-29 108.0 COG0425@1|root,COG0425@2|Bacteria,1MZA5@1224|Proteobacteria,1SH3F@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Belongs to the sulfur carrier protein TusA family - - - ko:K04085 ko04122,map04122 - - - ko00000,ko00001,ko01000,ko03016 - - - TusA k141_8078_5 1453501.JELR01000001_gene3172 2.75e-237 667.0 COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,1RP5S@1236|Gammaproteobacteria,465XU@72275|Alteromonadaceae 1236|Gammaproteobacteria S Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state bepA GO:0003674,GO:0003756,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005575,GO:0005623,GO:0006457,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016043,GO:0016787,GO:0016853,GO:0016860,GO:0016864,GO:0019538,GO:0022607,GO:0030163,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043163,GO:0043165,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044091,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044464,GO:0045229,GO:0046872,GO:0051603,GO:0061024,GO:0061077,GO:0070011,GO:0071704,GO:0071709,GO:0071840,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - - - - - - - - - - Peptidase_M48,TPR_19 k141_28282_1 267608.RSp0244 9.67e-06 53.5 COG1629@1|root,COG4771@2|Bacteria,1MX42@1224|Proteobacteria,2VMI9@28216|Betaproteobacteria,1JZXH@119060|Burkholderiaceae 28216|Betaproteobacteria P TonB-dependent hemoglobin transferrin lactoferrin bhuR - - ko:K16087 - - - - ko00000,ko02000 1.B.14.2 - - Plug,STN,TonB_dep_Rec k141_17744_1 1453501.JELR01000005_gene1571 9e-88 271.0 COG0845@1|root,COG0845@2|Bacteria,1N97Q@1224|Proteobacteria,1RXZP@1236|Gammaproteobacteria,46BQ3@72275|Alteromonadaceae 1236|Gammaproteobacteria M Multidrug transporter - - - - - - - - - - - - Biotin_lipoyl_2,GAF,HlyD_3,HlyD_D23 k141_36570_1 218284.CCDN010000008_gene4038 9.8e-104 314.0 COG2986@1|root,COG2986@2|Bacteria,1TPCW@1239|Firmicutes,4H9YS@91061|Bacilli,1ZC8Z@1386|Bacillus 91061|Bacilli E Histidine ammonia-lyase hutH - 4.3.1.3 ko:K01745 ko00340,ko01100,map00340,map01100 M00045 R01168 RC00361 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU39350 Lyase_aromatic k141_36570_2 218284.CCDN010000008_gene4039 2.18e-18 83.6 COG2987@1|root,COG2987@2|Bacteria,1TPZ9@1239|Firmicutes,4H9NH@91061|Bacilli,1ZCMM@1386|Bacillus 91061|Bacilli E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate hutU - 4.2.1.49 ko:K01712 ko00340,ko01100,map00340,map01100 M00045 R02914 RC00804 ko00000,ko00001,ko00002,ko01000 - - - Urocanase,Urocanase_C,Urocanase_N k141_37868_1 1294265.JCM21738_4346 2.36e-127 374.0 COG1508@1|root,COG1508@2|Bacteria,1TQ0H@1239|Firmicutes,4HA8T@91061|Bacilli,1ZBKU@1386|Bacillus 91061|Bacilli K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog rpoN - - ko:K03092 ko02020,ko05111,map02020,map05111 - - - ko00000,ko00001,ko03021 - - - Sigma54_AID,Sigma54_CBD,Sigma54_DBD k141_33170_2 1453501.JELR01000001_gene2978 0.0 880.0 COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,1RN7X@1236|Gammaproteobacteria,4665Q@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1960 Acyl-CoA dehydrogenases aidB GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003995,GO:0005488,GO:0005515,GO:0006355,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008470,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016491,GO:0016627,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0033554,GO:0042802,GO:0043565,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0055114,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K09456 - - - - ko00000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M k141_4641_2 1123252.ATZF01000002_gene2425 6.68e-48 162.0 COG2514@1|root,COG2514@2|Bacteria,1TPRF@1239|Firmicutes,4HAE7@91061|Bacilli 91061|Bacilli S glyoxalase catE - 1.13.11.2 ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 M00569 R00816,R04089,R05295,R05404,R05406,R07795 RC00387,RC00643,RC01075,RC01364,RC01914 ko00000,ko00001,ko00002,ko01000 - - - Glyoxalase k141_17745_1 866895.HBHAL_2665 1.17e-98 293.0 COG1388@1|root,COG1388@2|Bacteria,1V2ND@1239|Firmicutes,4HGIW@91061|Bacilli 91061|Bacilli M Lysin motif - - - - - - - - - - - - Gmad2,LysM k141_10675_1 218284.CCDN010000005_gene3280 2.47e-104 317.0 COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,4HAMK@91061|Bacilli,1ZBB4@1386|Bacillus 91061|Bacilli E ABC transporter substrate-binding protein oppA - - ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 k141_3453_1 398511.BpOF4_08970 5.59e-12 68.2 COG1457@1|root,COG1457@2|Bacteria,1V0CC@1239|Firmicutes,4HDNV@91061|Bacilli,1ZCSZ@1386|Bacillus 91061|Bacilli F Permease for cytosine/purines, uracil, thiamine, allantoin - - - ko:K10974 - - - - ko00000,ko02000 2.A.39.1 - - Transp_cyt_pur k141_2239_1 218284.CCDN010000001_gene1135 9.52e-129 374.0 COG0438@1|root,COG0438@2|Bacteria,1TPS8@1239|Firmicutes,4HA43@91061|Bacilli,1ZASJ@1386|Bacillus 91061|Bacilli M N-acetyl-alpha-D-glucosaminyl L-malate synthase bshA - - ko:K00754 - - - - ko00000,ko01000 - GT4 - Glyco_transf_4,Glycos_transf_1 k141_8079_1 1042377.AFPJ01000037_gene2898 0.000241 43.1 COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,1RNYI@1236|Gammaproteobacteria,4642M@72275|Alteromonadaceae 1236|Gammaproteobacteria M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxD GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 ko:K02536 ko00540,ko01100,map00540,map01100 M00060 R04550 RC00039,RC00166 ko00000,ko00001,ko00002,ko01000,ko01005 - - ic_1306.c0216 Hexapep,Hexapep_2,LpxD k141_21247_1 218284.CCDN010000001_gene803 1.38e-221 619.0 COG0697@1|root,COG0697@2|Bacteria,1TP7K@1239|Firmicutes,4HBWN@91061|Bacilli,1ZAS9@1386|Bacillus 91061|Bacilli EG Bacillus/Clostridium GerA spore germination protein spoVAF - - ko:K06408 - - - - ko00000 - - - GerA k141_30562_2 1196029.ALIM01000023_gene752 1.16e-52 170.0 COG1670@1|root,COG1670@2|Bacteria,1V40F@1239|Firmicutes,4HGKM@91061|Bacilli,1ZRFD@1386|Bacillus 91061|Bacilli J Acetyltransferase (GNAT) domain - - 2.3.1.128 ko:K03790 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 k141_17749_1 218284.CCDN010000008_gene4149 2.12e-98 294.0 COG1294@1|root,COG1294@2|Bacteria,1TPYX@1239|Firmicutes,4HA9T@91061|Bacilli,1ZCH6@1386|Bacillus 91061|Bacilli C COG1294 Cytochrome bd-type quinol oxidase, subunit 2 ythB - 1.10.3.14 ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - Cyt_bd_oxida_II k141_36864_1 1042377.AFPJ01000008_gene2004 9.11e-222 620.0 COG1012@1|root,COG1012@2|Bacteria,1NRUR@1224|Proteobacteria,1SMSX@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Aldehyde dehydrogenase family - - - - - - - - - - - - Aldedh k141_14278_2 1219076.N646_1751 3.26e-51 162.0 COG5007@1|root,COG5007@2|Bacteria,1N1WJ@1224|Proteobacteria,1SCAR@1236|Gammaproteobacteria,1XXSQ@135623|Vibrionales 135623|Vibrionales K Belongs to the BolA IbaG family yrbA - - - - - - - - - - - BolA k141_14278_3 1280001.BAOA01000048_gene1865 1.25e-56 177.0 COG3113@1|root,COG3113@2|Bacteria,1NGIE@1224|Proteobacteria,1SGH6@1236|Gammaproteobacteria,1XYDH@135623|Vibrionales 135623|Vibrionales S NTP binding protein (contains STAS domain) yrbB - - ko:K07122 ko02010,map02010 M00210 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27.3 - - STAS_2 k141_15501_2 511.JT27_05490 1.15e-19 92.0 COG2423@1|root,COG2423@2|Bacteria,1MWH6@1224|Proteobacteria,2VIRU@28216|Betaproteobacteria,3T2J9@506|Alcaligenaceae 28216|Betaproteobacteria E ornithine cyclodeaminase - - 1.5.1.1,4.3.1.12 ko:K01750,ko:K19743 ko00310,ko00330,ko00960,ko01100,ko01110,ko01130,ko01230,map00310,map00330,map00960,map01100,map01110,map01130,map01230 - R00671,R01246,R01249,R02201,R02203 RC00135,RC00354 ko00000,ko00001,ko01000 - - - OCD_Mu_crystall k141_19053_2 430498.S8APU0 7.99e-10 59.3 COG0365@1|root,KOG1175@2759|Eukaryota,38BR4@33154|Opisthokonta,3NUTI@4751|Fungi,3QM4K@4890|Ascomycota 4751|Fungi I Acetyl-coenzyme a synthetase ACS2 GO:0000166,GO:0001302,GO:0003674,GO:0003824,GO:0003987,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0005737,GO:0005739,GO:0005829,GO:0006082,GO:0006083,GO:0006084,GO:0006085,GO:0006091,GO:0006113,GO:0006139,GO:0006163,GO:0006164,GO:0006325,GO:0006464,GO:0006473,GO:0006475,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007568,GO:0007569,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015976,GO:0015980,GO:0016020,GO:0016021,GO:0016043,GO:0016054,GO:0016208,GO:0016405,GO:0016569,GO:0016570,GO:0016573,GO:0016874,GO:0016877,GO:0016878,GO:0016879,GO:0016880,GO:0016999,GO:0017001,GO:0017076,GO:0017144,GO:0018130,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019438,GO:0019538,GO:0019637,GO:0019654,GO:0019693,GO:0019752,GO:0030554,GO:0031224,GO:0031974,GO:0031981,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0045733,GO:0046390,GO:0046395,GO:0046483,GO:0048869,GO:0051186,GO:0051188,GO:0051276,GO:0055086,GO:0055114,GO:0070013,GO:0071616,GO:0071704,GO:0071840,GO:0072329,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACAS_N,AMP-binding,AMP-binding_C k141_16670_1 1279017.AQYJ01000020_gene1225 3.5e-177 497.0 COG2264@1|root,COG2264@2|Bacteria,1MUPC@1224|Proteobacteria,1RNAR@1236|Gammaproteobacteria,4650B@72275|Alteromonadaceae 1236|Gammaproteobacteria J Ribosomal protein L11 methyltransferase prmA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006480,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0018011,GO:0018012,GO:0018022,GO:0018023,GO:0018193,GO:0018194,GO:0018205,GO:0019538,GO:0031365,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 - ko:K02687 - - - - ko00000,ko01000,ko03009 - - - PrmA k141_16670_2 1279017.AQYJ01000020_gene1226 4.55e-126 377.0 COG1273@1|root,COG1273@2|Bacteria,1MWCU@1224|Proteobacteria,1RYQ0@1236|Gammaproteobacteria,46705@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF3426) - - - - - - - - - - - - DUF3426,zinc_ribbon_4,zinc_ribbon_5 k141_16670_3 1279017.AQYJ01000020_gene1227 2.34e-217 602.0 COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,1RMJP@1236|Gammaproteobacteria,464KZ@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines dusB GO:0002943,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009314,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016491,GO:0016627,GO:0017150,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050896,GO:0055114,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 - ko:K05540 - - - - ko00000,ko01000,ko03016 - - - Dus k141_17875_1 1207076.ALAT01000215_gene4097 6.25e-45 160.0 COG0665@1|root,COG0665@2|Bacteria,1MVGP@1224|Proteobacteria,1RNJ9@1236|Gammaproteobacteria,1Z0KF@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria E COG0665 Glycine D-amino acid oxidases (deaminating) ordL GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0044424,GO:0044464,GO:0055114 - ko:K09471 ko00330,ko01100,map00330,map01100 M00136 R07415 RC00062 ko00000,ko00001,ko00002,ko01000 - - - DAO k141_44_1 218284.CCDN010000001_gene982 7.99e-179 502.0 COG0334@1|root,COG0334@2|Bacteria,1TQU2@1239|Firmicutes,4HAB2@91061|Bacilli,1ZB55@1386|Bacillus 91061|Bacilli E Belongs to the Glu Leu Phe Val dehydrogenases family ldh - 1.4.1.9 ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 - R01088,R01434,R02196 RC00006,RC00036 ko00000,ko00001,ko01000 - - - ELFV_dehydrog,ELFV_dehydrog_N k141_3616_1 1121352.JHZP01000001_gene320 2.06e-40 151.0 COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,2VK5J@28216|Betaproteobacteria,2KPD7@206351|Neisseriales 206351|Neisseriales F 5'-nucleotidase, C-terminal domain ushA - 3.1.3.5,3.6.1.45 ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - 5_nucleotid_C,Metallophos k141_2412_1 1121921.KB898706_gene3064 1.11e-96 320.0 COG3866@1|root,COG3866@2|Bacteria,1QPFF@1224|Proteobacteria,1RQEM@1236|Gammaproteobacteria,2PMMI@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria G Amb_all pel1C - - - - - - - - - - - CBM_35,CBM_5_12_2,CBM_6,Pec_lyase_C,RicinB_lectin_2 k141_4801_1 997296.PB1_15344 7.11e-41 157.0 COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,4H9M4@91061|Bacilli,1ZBWR@1386|Bacillus 91061|Bacilli S Competence protein ComEC comEC - - ko:K02238 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - Competence,DUF4131,Lactamase_B k141_15502_1 1408303.JNJJ01000053_gene1537 4.86e-75 239.0 COG1104@1|root,COG1104@2|Bacteria,1TPYU@1239|Firmicutes,4HA5J@91061|Bacilli,1ZCRY@1386|Bacillus 91061|Bacilli E Cysteine desulfurase nifS - 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - - Aminotran_5 k141_22623_1 1116375.VEJY3_17796 2.03e-189 538.0 COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,1RMPS@1236|Gammaproteobacteria,1XTWB@135623|Vibrionales 135623|Vibrionales H Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration nnrD - 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 - - - - ko00000,ko01000 - - - Carb_kinase,YjeF_N k141_24985_1 1453501.JELR01000002_gene1275 1.33e-125 362.0 COG0668@1|root,COG0668@2|Bacteria,1N596@1224|Proteobacteria,1RQZP@1236|Gammaproteobacteria,464UB@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0668 Small-conductance mechanosensitive channel - - - ko:K03442 - - - - ko00000,ko02000 1.A.23.2 - - MS_channel,TM_helix k141_17876_1 218284.CCDN010000002_gene2915 3.23e-111 335.0 COG0661@1|root,COG0661@2|Bacteria,1TPIV@1239|Firmicutes,4HBW3@91061|Bacilli,1ZBPH@1386|Bacillus 91061|Bacilli S ABC1 family ubiB - - - - - - - - - - - ABC1,APH,RIO1 k141_27363_1 218284.CCDN010000001_gene1878 1.04e-193 540.0 COG1052@1|root,COG1052@2|Bacteria,1UI1W@1239|Firmicutes,4HA71@91061|Bacilli,1ZAZJ@1386|Bacillus 91061|Bacilli CH Dipicolinate synthase subunit A dpaA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0016618,GO:0030267,GO:0044424,GO:0044444,GO:0044464,GO:0055114 - ko:K06410 - - - - ko00000 - - iYO844.BSU16730 2-Hacid_dh_C,AlaDh_PNT_C,DpaA_N k141_27363_2 218284.CCDN010000001_gene1877 1.21e-134 382.0 COG0452@1|root,COG0452@2|Bacteria,1TQPT@1239|Firmicutes,4HAU9@91061|Bacilli,1ZCJQ@1386|Bacillus 91061|Bacilli H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA) spoVFB - - ko:K06411 - - - - ko00000 - - iYO844.BSU16740 Flavoprotein k141_27363_3 218284.CCDN010000001_gene1876 1.1e-227 630.0 COG0136@1|root,COG0136@2|Bacteria,1TPC6@1239|Firmicutes,4HA9H@91061|Bacilli,1ZAVS@1386|Bacillus 91061|Bacilli E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate asd - 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC k141_8379_1 1121938.AUDY01000013_gene3177 1.82e-60 202.0 COG1620@1|root,COG1620@2|Bacteria,1TQNM@1239|Firmicutes,4HAF3@91061|Bacilli,3NFNB@45667|Halobacillus 91061|Bacilli C L-lactate permease - - - ko:K03303 - - - - ko00000,ko02000 2.A.14 - - Lactate_perm k141_8379_2 218284.CCDN010000007_gene3904 1.33e-50 170.0 COG1168@1|root,COG1168@2|Bacteria,1TP5G@1239|Firmicutes,4H9PE@91061|Bacilli,1ZCQC@1386|Bacillus 91061|Bacilli E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities patB - 4.4.1.8 ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 - R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 k141_35705_1 218284.CCDN010000006_gene3685 5.92e-115 352.0 COG0653@1|root,COG0653@2|Bacteria,1TPEY@1239|Firmicutes,4HA22@91061|Bacilli,1ZAXF@1386|Bacillus 91061|Bacilli U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW k141_26202_1 218284.CCDN010000007_gene3962 4.63e-65 204.0 COG3343@1|root,COG3343@2|Bacteria,1V6WX@1239|Firmicutes,4HIUK@91061|Bacilli,1ZH95@1386|Bacillus 91061|Bacilli K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling rpoE GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 - ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 - - - HARE-HTH k141_30952_1 218284.CCDN010000002_gene2347 6.53e-93 288.0 COG1164@1|root,COG1164@2|Bacteria,1TQ5W@1239|Firmicutes,4HU91@91061|Bacilli,1ZFB6@1386|Bacillus 91061|Bacilli E oligoendopeptidase - - - - - - - - - - - - Peptidase_M3,Peptidase_M3_N k141_20237_2 1410632.JHWW01000002_gene2239 1.01e-10 65.1 COG1843@1|root,COG1843@2|Bacteria,1VF85@1239|Firmicutes,24QKD@186801|Clostridia,27P9H@186928|unclassified Lachnospiraceae 186801|Clostridia N Required for flagellar hook formation. May act as a scaffolding protein flgD - - ko:K02389 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FLgD_tudor,FlgD k141_20237_3 454957.IA64_15545 1.45e-28 115.0 COG1749@1|root,COG1749@2|Bacteria,1MU5J@1224|Proteobacteria,1SA5Y@1236|Gammaproteobacteria,1XAUA@135614|Xanthomonadales 135614|Xanthomonadales N Flagellar basal body rod FlgEFG protein C-terminal - - - - - - - - - - - - Flg_bb_rod,Flg_bbr_C k141_15503_1 1136163.M565_ctg5P0835 6.97e-05 47.4 2EPXK@1|root,33HI4@2|Bacteria,1NHK6@1224|Proteobacteria,1THI6@1236|Gammaproteobacteria,1XW1F@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_15503_2 1085623.GNIT_1612 9.49e-10 60.8 COG1902@1|root,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,1RR6H@1236|Gammaproteobacteria,4664Z@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family - - - - - - - - - - - - Oxidored_FMN k141_11914_1 441769.ABFU01000028_gene1293 2.21e-197 554.0 COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,4H9NW@91061|Bacilli,1ZCU1@1386|Bacillus 91061|Bacilli L RNA-directed DNA polymerase (reverse transcriptase) - - - - - - - - - - - - GIIM,RVT_1 k141_19055_2 290398.Csal_1622 1.26e-26 99.8 2FCF3@1|root,344IK@2|Bacteria,1P294@1224|Proteobacteria,1SREJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_19055_3 42565.FP66_07950 8.52e-11 61.6 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1XH7F@135619|Oceanospirillales 135619|Oceanospirillales L DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA rhlB - 3.6.4.13 ko:K03732 ko03018,map03018 M00394 - - ko00000,ko00001,ko00002,ko01000,ko03019 - - - DEAD,Helicase_C k141_35706_1 218284.CCDN010000007_gene3981 1.98e-42 145.0 2AUKD@1|root,31K93@2|Bacteria,1V6PK@1239|Firmicutes,4HI5F@91061|Bacilli,1ZEE3@1386|Bacillus 91061|Bacilli S stage II sporulation protein R spoIIR - - ko:K06387 - - - - ko00000 - - - Spore_II_R k141_17878_2 1196031.ALEG01000072_gene954 5.9e-12 61.6 2DRQR@1|root,33CNQ@2|Bacteria,1VGGC@1239|Firmicutes,4HR2A@91061|Bacilli,1ZJ1V@1386|Bacillus 91061|Bacilli S Small, acid-soluble spore protein, gamma-type sspE - - ko:K06422 - - - - ko00000 - - - SASP_gamma k141_32120_1 218284.CCDN010000002_gene2214 1.25e-169 482.0 COG0477@1|root,COG2814@2|Bacteria,1TSR2@1239|Firmicutes,4HD8G@91061|Bacilli,1ZCGV@1386|Bacillus 91061|Bacilli EGP COG0477 Permeases of the major facilitator superfamily - - - - - - - - - - - - MFS_1,MFS_3 k141_4803_1 218284.CCDN010000010_gene4373 5.42e-145 441.0 COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,4HA24@91061|Bacilli,1ZDK0@1386|Bacillus 91061|Bacilli K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoC GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 k141_13130_1 218284.CCDN010000001_gene1870 3.36e-122 373.0 COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,4H9WA@91061|Bacilli,1ZANX@1386|Bacillus 91061|Bacilli D Belongs to the FtsK SpoIIIE SftA family ftsK GO:0000003,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma k141_15505_1 997296.PB1_13489 7.68e-78 250.0 COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4H9TK@91061|Bacilli,1ZBTF@1386|Bacillus 91061|Bacilli S COG0488 ATPase components of ABC transporters with duplicated ATPase domains yfmR - - ko:K15738 - - - - ko00000,ko02000 3.A.1.120.6 - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn k141_26203_1 1042377.AFPJ01000030_gene438 1.96e-71 228.0 COG0154@1|root,COG0154@2|Bacteria,1MW3Z@1224|Proteobacteria,1RP33@1236|Gammaproteobacteria,464XC@72275|Alteromonadaceae 1236|Gammaproteobacteria J Amidase - - 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Amidase k141_26203_2 1453501.JELR01000002_gene117 9.34e-207 577.0 COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RNXA@1236|Gammaproteobacteria,465VR@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0436 Aspartate tyrosine aromatic aminotransferase - - 4.1.1.82 ko:K09459,ko:K10907 ko00440,ko01100,ko01120,ko01130,map00440,map01100,map01120,map01130 - R04053 RC00506 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 k141_4804_1 1480694.DC28_11590 2.3e-19 92.8 COG0399@1|root,COG0399@2|Bacteria,2J62G@203691|Spirochaetes 203691|Spirochaetes E Belongs to the DegT DnrJ EryC1 family spsC - - - - - - - - - - - DegT_DnrJ_EryC1 k141_3620_1 218284.CCDN010000006_gene3656 1.72e-116 351.0 COG0556@1|root,COG0556@2|Bacteria,1TPKB@1239|Firmicutes,4HB81@91061|Bacilli,1ZC50@1386|Bacillus 91061|Bacilli L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage uvrB - - ko:K03702 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - Helicase_C,ResIII,UVR,UvrB k141_16671_2 1116375.VEJY3_11825 3.85e-153 439.0 COG2771@1|root,COG2771@2|Bacteria,1PDSX@1224|Proteobacteria,1TBHP@1236|Gammaproteobacteria,1XXYQ@135623|Vibrionales 135623|Vibrionales K COG2771 DNA-binding HTH domain-containing proteins - - - - - - - - - - - - GerE k141_8382_1 218284.CCDN010000001_gene1780 4.4e-46 150.0 291YW@1|root,2ZPID@2|Bacteria,1V3V6@1239|Firmicutes,4HGYJ@91061|Bacilli,1ZG6E@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2621) yneK - - - - - - - - - - - DUF2621 k141_8382_2 218284.CCDN010000001_gene1779 1.86e-48 167.0 COG3852@1|root,COG3852@2|Bacteria,1TRH0@1239|Firmicutes,4HD4A@91061|Bacilli,1ZDWU@1386|Bacillus 91061|Bacilli T COG0642 Signal transduction histidine kinase kinC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 ko:K07698 ko02020,map02020 M00485 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS,PAS_3,PAS_9 k141_4805_1 1294265.JCM21738_4077 7.17e-124 372.0 COG1948@1|root,COG4886@1|root,COG4880@2|Bacteria,COG4886@2|Bacteria,1TQK0@1239|Firmicutes,4H9YF@91061|Bacilli,1ZDVB@1386|Bacillus 91061|Bacilli L Beta propeller domain - - - - - - - - - - - - Beta_propel,Big_5,Cu_amine_oxidN1 k141_3621_1 218284.CCDN010000009_gene4312 8.68e-39 136.0 COG3595@1|root,COG3595@2|Bacteria,1V94C@1239|Firmicutes,4HJYP@91061|Bacilli,1ZEE4@1386|Bacillus 91061|Bacilli S Putative adhesin liaG - - ko:K11621 ko02020,map02020 - - - ko00000,ko00001 - - - DUF4097 k141_3621_2 218284.CCDN010000009_gene4310 2.09e-44 159.0 COG1289@1|root,COG1289@2|Bacteria,1U18W@1239|Firmicutes,4IJPB@91061|Bacilli,1ZDV7@1386|Bacillus 91061|Bacilli S Fusaric acid resistance protein-like - - - - - - - - - - - - FUSC,FUSC_2 k141_19057_1 218284.CCDN010000002_gene2696 2.24e-67 218.0 COG0124@1|root,COG0124@2|Bacteria,1TP3D@1239|Firmicutes,4HAWF@91061|Bacilli,1ZDID@1386|Bacillus 91061|Bacilli J histidyl-tRNA synthetase - - 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_His k141_30955_2 880073.Calab_1874 8.97e-62 206.0 COG0481@1|root,COG0481@2|Bacteria,2NNXG@2323|unclassified Bacteria 2|Bacteria M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner lepA - - ko:K03596 ko05134,map05134 - - - ko00000,ko00001 - - - EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C k141_9530_1 1116375.VEJY3_11895 3.44e-203 573.0 COG3249@1|root,COG3249@2|Bacteria,1N0PD@1224|Proteobacteria,1S9C4@1236|Gammaproteobacteria,1XU1W@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria VV2512 - - ko:K09938 - - - - ko00000 - - - DUF2066 k141_9530_2 1116375.VEJY3_11890 1.87e-95 278.0 COG3308@1|root,COG3308@2|Bacteria,1N134@1224|Proteobacteria,1S8XA@1236|Gammaproteobacteria,1XY46@135623|Vibrionales 135623|Vibrionales S Predicted membrane protein (DUF2069) - - - - - - - - - - - - DUF2069 k141_9530_3 1116375.VEJY3_11885 1.5e-128 366.0 COG0655@1|root,COG0655@2|Bacteria,1MW7N@1224|Proteobacteria,1S23B@1236|Gammaproteobacteria,1XTDI@135623|Vibrionales 135623|Vibrionales S COG0655 Multimeric flavodoxin WrbA wrbA - 1.6.5.2 ko:K03809 ko00130,ko01110,map00130,map01110 - R02964,R03643,R03816 RC00819 ko00000,ko00001,ko01000 - - - FMN_red k141_9530_4 1116375.VEJY3_11880 1.7e-70 213.0 COG1393@1|root,COG1393@2|Bacteria,1MZ4Z@1224|Proteobacteria,1S8XH@1236|Gammaproteobacteria,1XXT8@135623|Vibrionales 135623|Vibrionales C COG1393 Arsenate reductase and related proteins, glutaredoxin family arsC - 1.20.4.1 ko:K00537 - - - - ko00000,ko01000 - - - ArsC k141_9530_5 223926.28807271 3.66e-279 772.0 COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,1RP5S@1236|Gammaproteobacteria,1XUZK@135623|Vibrionales 135623|Vibrionales S Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state yfgC - - - - - - - - - - - Peptidase_M48,TPR_19,TPR_8 k141_9530_6 1280001.BAOA01000081_gene3021 1.31e-33 117.0 COG0425@1|root,COG0425@2|Bacteria,1NGHP@1224|Proteobacteria,1SX2D@1236|Gammaproteobacteria,1XZIM@135623|Vibrionales 135623|Vibrionales O Belongs to the sulfur carrier protein TusA family - - - - - - - - - - - - TusA k141_9530_7 1116375.VEJY3_11865 1.45e-224 622.0 COG0628@1|root,COG0628@2|Bacteria,1MW0B@1224|Proteobacteria,1RPVP@1236|Gammaproteobacteria,1XV05@135623|Vibrionales 135623|Vibrionales S AI-2E family transporter perM - - ko:K03548 - - - - ko00000,ko02000 2.A.86.1 - - AI-2E_transport k141_9530_8 223926.28807268 2.14e-108 312.0 COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,1RQ7F@1236|Gammaproteobacteria,1XSCX@135623|Vibrionales 135623|Vibrionales O COG1225 Peroxiredoxin bcp - 1.11.1.15 ko:K03564 - - - - ko00000,ko01000 - - - AhpC-TSA k141_13153_3 1121921.KB898710_gene629 1.05e-52 173.0 COG3101@1|root,COG3101@2|Bacteria,1MWTG@1224|Proteobacteria,1RNHD@1236|Gammaproteobacteria,2PNQ6@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria S Elongation factor P hydroxylase yfcM GO:0003674,GO:0003824,GO:0004497,GO:0005488,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016705,GO:0016709,GO:0017185,GO:0018126,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046872,GO:0055114,GO:0071704,GO:0072580,GO:1901260,GO:1901564 - ko:K09906 - - - - ko00000,ko01000,ko03012 - - - EpmC k141_13153_4 1279017.AQYJ01000029_gene3338 2.45e-147 416.0 28J4W@1|root,2Z90S@2|Bacteria,1R68N@1224|Proteobacteria,1RRQ2@1236|Gammaproteobacteria,465HF@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_13153_5 1279017.AQYJ01000029_gene3337 2.71e-41 137.0 COG0425@1|root,COG0425@2|Bacteria,1MZA5@1224|Proteobacteria,1S8TC@1236|Gammaproteobacteria,468CY@72275|Alteromonadaceae 1236|Gammaproteobacteria O Sulfur carrier protein which probably makes part of a sulfur-relay system tusA GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0019725,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042592,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048878,GO:0051186,GO:0051188,GO:0051189,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0090407,GO:0097163,GO:0140104,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - ko:K04085 ko04122,map04122 - - - ko00000,ko00001,ko01000,ko03016 - - - TusA k141_13153_6 1279017.AQYJ01000029_gene3336 6.89e-47 152.0 COG2329@1|root,COG2329@2|Bacteria,1N861@1224|Proteobacteria,1SC9H@1236|Gammaproteobacteria,468QF@72275|Alteromonadaceae 1236|Gammaproteobacteria S enzyme involved in biosynthesis of extracellular polysaccharides - - - - - - - - - - - - ABM k141_13153_7 32051.SynWH7803_0930 7.41e-66 209.0 COG3571@1|root,COG3571@2|Bacteria,1GN2K@1117|Cyanobacteria,1H09C@1129|Synechococcus 1117|Cyanobacteria S hydrolase of the alpha beta-hydrolase fold - - - ko:K07020 - - - - ko00000 - - - DLH k141_13153_8 1453501.JELR01000001_gene2722 7.29e-35 120.0 COG3089@1|root,COG3089@2|Bacteria,1PCAQ@1224|Proteobacteria,1SGN9@1236|Gammaproteobacteria,46CTY@72275|Alteromonadaceae 1236|Gammaproteobacteria S Uncharacterised protein family (UPF0270) IV02_22800 - - ko:K09898 - - - - ko00000 - - - UPF0270 k141_13153_9 1279017.AQYJ01000029_gene3333 3.47e-137 396.0 COG4798@1|root,COG4798@2|Bacteria,1NNHX@1224|Proteobacteria,1RN1A@1236|Gammaproteobacteria,465Q4@72275|Alteromonadaceae 1236|Gammaproteobacteria S Methyltransferase - - - - - - - - - - - - - k141_13153_11 1279017.AQYJ01000029_gene3331 8.44e-86 256.0 COG2716@1|root,COG2716@2|Bacteria,1MZJ6@1224|Proteobacteria,1S39E@1236|Gammaproteobacteria,46837@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG2716 Glycine cleavage system regulatory protein - - - - - - - - - - - - ACT,ACT_4,ACT_6 k141_13153_12 1042377.AFPJ01000036_gene1175 6.03e-85 253.0 COG0219@1|root,COG0219@2|Bacteria,1RCY4@1224|Proteobacteria,1S3PI@1236|Gammaproteobacteria,46713@72275|Alteromonadaceae 1236|Gammaproteobacteria J Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide trmL GO:0001510,GO:0002128,GO:0002130,GO:0002131,GO:0002132,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016427,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052665,GO:0052666,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.207 ko:K03216 - - - - ko00000,ko01000,ko03016 - - - SpoU_methylase k141_13153_13 1453501.JELR01000001_gene2726 6.81e-112 323.0 COG0716@1|root,COG0716@2|Bacteria,1QRBW@1224|Proteobacteria,1RMED@1236|Gammaproteobacteria,466W7@72275|Alteromonadaceae 1236|Gammaproteobacteria C Low-potential electron donor to a number of redox enzymes fldB - - ko:K03839,ko:K03840 - - - - ko00000 - - - Flavodoxin_1 k141_13153_14 1042377.AFPJ01000036_gene1173 4.86e-160 472.0 COG0665@1|root,COG4121@1|root,COG0665@2|Bacteria,COG4121@2|Bacteria,1MZW5@1224|Proteobacteria,1RMTE@1236|Gammaproteobacteria,464VK@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 mnmC GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0004808,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016491,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363 2.1.1.61 ko:K15461 - - R00601,R08702 RC00003,RC00053,RC00060,RC01483 ko00000,ko01000,ko03016 - - - DAO,Methyltransf_30 k141_8404_1 234267.Acid_2410 5.17e-55 192.0 COG1964@1|root,COG1964@2|Bacteria,3Y2WC@57723|Acidobacteria 57723|Acidobacteria S PFAM Radical SAM - - - - - - - - - - - - Fer4_12,Radical_SAM k141_2447_2 997296.PB1_09532 1.36e-41 142.0 COG0107@1|root,COG0107@2|Bacteria,1TP0W@1239|Firmicutes,4HAAM@91061|Bacilli,1ZAUX@1386|Bacillus 91061|Bacilli E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit hisF GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS14115 His_biosynth k141_15533_1 665959.HMPREF1013_03373 4.94e-66 213.0 COG2072@1|root,COG2072@2|Bacteria,1TT0U@1239|Firmicutes,4HEEM@91061|Bacilli,1ZCKW@1386|Bacillus 91061|Bacilli P FAD-NAD(P)-binding - - - - - - - - - - - - K_oxygenase,NAD_binding_9,Pyr_redox_3 k141_29758_1 218284.CCDN010000001_gene1293 9.43e-212 588.0 2CEJD@1|root,2Z81V@2|Bacteria,1UD9R@1239|Firmicutes,4HAPP@91061|Bacilli,1ZC32@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3900) yetN - - - - - - - - - - - DUF3898,DUF3900 k141_4827_1 1042377.AFPJ01000024_gene813 2.46e-206 585.0 COG0471@1|root,COG0569@1|root,COG0471@2|Bacteria,COG0569@2|Bacteria,1MU0K@1224|Proteobacteria,1RMI1@1236|Gammaproteobacteria,464A6@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0471 Di- and tricarboxylate transporters - - - - - - - - - - - - CitMHS,TrkA_C k141_77_1 1453501.JELR01000001_gene2715 1.18e-125 367.0 COG0111@1|root,COG0111@2|Bacteria,1N5TD@1224|Proteobacteria,1RMFW@1236|Gammaproteobacteria,465GC@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate pdxB GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0033711,GO:0034641,GO:0036001,GO:0036094,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.1.1.290 ko:K03473 ko00750,ko01100,map00750,map01100 M00124 R04210 RC00084 ko00000,ko00001,ko00002,ko01000 - - iZ_1308.Z3582 2-Hacid_dh,2-Hacid_dh_C,DUF3410 k141_25002_1 218284.CCDN010000001_gene1748 1.94e-140 403.0 COG1366@1|root,COG1366@2|Bacteria,1V1QF@1239|Firmicutes,4HGBT@91061|Bacilli,1ZDJX@1386|Bacillus 91061|Bacilli T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) yojH - - ko:K17763 - - - - ko00000,ko03021 - - - STAS k141_2449_1 1294265.JCM21738_4880 3.54e-110 323.0 COG0470@1|root,COG0470@2|Bacteria,1TRVS@1239|Firmicutes,4HA3T@91061|Bacilli,1ZBDA@1386|Bacillus 91061|Bacilli L DNA polymerase III holB GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576 2.7.7.7 ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNApol3-delta_C k141_2449_2 1294265.JCM21738_4881 9.88e-36 124.0 COG1728@1|root,COG1728@2|Bacteria,1VF6M@1239|Firmicutes,4HP8D@91061|Bacilli,1ZFYU@1386|Bacillus 91061|Bacilli S protein conserved in bacteria yaaR - - ko:K09770 - - - - ko00000 - - - DUF327 k141_8405_1 1294265.JCM21738_4564 6.51e-82 245.0 COG0311@1|root,COG0311@2|Bacteria,1V3I6@1239|Firmicutes,4HFSZ@91061|Bacilli,1ZD5C@1386|Bacillus 91061|Bacilli H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS pdxT GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 ko:K08681 ko00750,map00750 - R07456 RC00010,RC01783,RC03043 ko00000,ko00001,ko01000 - - - SNO k141_32136_1 1279017.AQYJ01000022_gene2578 4.69e-165 475.0 COG0534@1|root,COG0534@2|Bacteria,1MVRV@1224|Proteobacteria,1RRDQ@1236|Gammaproteobacteria,46495@72275|Alteromonadaceae 1236|Gammaproteobacteria V COG0534 Na -driven multidrug efflux pump - - - - - - - - - - - - MatE k141_32136_2 614083.AWQR01000009_gene648 1.34e-21 92.4 COG0454@1|root,COG0456@2|Bacteria,1RIE6@1224|Proteobacteria,2VUIW@28216|Betaproteobacteria,4AE54@80864|Comamonadaceae 28216|Betaproteobacteria K Ribosomal-protein-alanine acetyltransferase rimI - 2.3.1.128 ko:K03789,ko:K14742 - - - - ko00000,ko01000,ko03009,ko03016 - - - Acetyltransf_1,Peptidase_M22 k141_32136_3 1453501.JELR01000001_gene3274 9.49e-84 258.0 2BZVX@1|root,32R5V@2|Bacteria,1RKXP@1224|Proteobacteria,1T470@1236|Gammaproteobacteria,468AV@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_32136_4 1042377.AFPJ01000002_gene520 0.0 888.0 COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,1RMWE@1236|Gammaproteobacteria,464RE@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) leuA GO:0003674,GO:0003824,GO:0003852,GO:0003985,GO:0003988,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046912,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.3.13 ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 M00432 R01213 RC00004,RC00470,RC02754 br01601,ko00000,ko00001,ko00002,ko01000 - - iSFV_1184.SFV_0066 HMGL-like,LeuA_dimer k141_78_1 1453501.JELR01000006_gene14 1.39e-80 262.0 COG4223@1|root,COG4223@2|Bacteria,1N10X@1224|Proteobacteria,1RYCQ@1236|Gammaproteobacteria,46D2D@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF1631) - - - - - - - - - - - - DUF1631 k141_21471_1 218284.CCDN010000001_gene1920 7.11e-93 280.0 COG1868@1|root,COG1868@2|Bacteria,1TPTM@1239|Firmicutes,4HAAY@91061|Bacilli,1ZCI6@1386|Bacillus 91061|Bacilli N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation fliM GO:0005575,GO:0005623,GO:0005886,GO:0006935,GO:0008150,GO:0009288,GO:0009425,GO:0009605,GO:0016020,GO:0040011,GO:0042221,GO:0042330,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0050896,GO:0050918,GO:0071944 - ko:K02416 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02035 - - - FliM,FliMN_C k141_30980_2 634956.Geoth_1523 2.76e-36 132.0 COG1609@1|root,COG1609@2|Bacteria,1TPZJ@1239|Firmicutes,4HC9Z@91061|Bacilli,1WFPZ@129337|Geobacillus 91061|Bacilli K helix_turn _helix lactose operon repressor galR - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 k141_20265_4 218284.CCDN010000005_gene3295 1.17e-15 73.9 COG4116@1|root,COG4116@2|Bacteria,1VA56@1239|Firmicutes,4HMNE@91061|Bacilli,1ZH0U@1386|Bacillus 91061|Bacilli S protein conserved in bacteria yjbK - - - - - - - - - - - CYTH k141_26245_1 42565.FP66_08890 3.92e-114 335.0 COG2942@1|root,COG2942@2|Bacteria,1MX1J@1224|Proteobacteria,1RSCF@1236|Gammaproteobacteria,1XIH5@135619|Oceanospirillales 135619|Oceanospirillales G N-acylglucosamine 2-epimerase - - - - - - - - - - - - GlcNAc_2-epim k141_21498_1 40373.F991_00468 1.08e-40 144.0 2AI8C@1|root,318NY@2|Bacteria,1Q0PE@1224|Proteobacteria,1TNPX@1236|Gammaproteobacteria,3NR1W@468|Moraxellaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_25019_1 1122137.AQXF01000003_gene2090 7.4e-33 134.0 COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,2TSGE@28211|Alphaproteobacteria 28211|Alphaproteobacteria U COG0457 FOG TPR repeat - - - - - - - - - - - - Sulfotransfer_3,TPR_16,TPR_19,TPR_8 k141_29786_2 1463854.JOHT01000017_gene3135 9.77e-43 152.0 COG1262@1|root,COG1262@2|Bacteria,2GK9Q@201174|Actinobacteria 201174|Actinobacteria KLT Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma- L-glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine egtB GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006575,GO:0006577,GO:0006578,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016053,GO:0016054,GO:0016491,GO:0019439,GO:0019752,GO:0034641,GO:0042398,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0052698,GO:0052699,GO:0052701,GO:0052703,GO:0052704,GO:0052708,GO:0052803,GO:0052805,GO:0055114,GO:0071704,GO:0097164,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606 1.14.99.50 ko:K18912 ko00340,map00340 - R11013 RC03323,RC03324 ko00000,ko00001,ko01000 - - - DinB_2,FGE-sulfatase k141_34563_2 218284.CCDN010000005_gene3199 4.18e-140 399.0 COG1234@1|root,COG1234@2|Bacteria,1V1TF@1239|Firmicutes,4HFNV@91061|Bacilli,1ZCZE@1386|Bacillus 91061|Bacilli S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III yhfI GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 - - - - - - - - - - Lactamase_B,Lactamase_B_2 k141_33363_1 243233.MCA1349 6.27e-94 293.0 COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,1RNKN@1236|Gammaproteobacteria,1XEVB@135618|Methylococcales 135618|Methylococcales C NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus - - 1.6.5.3 ko:K00341 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_M,Proton_antipo_N k141_19090_1 1294265.JCM21738_3572 5.75e-06 47.4 COG4963@1|root,COG4963@2|Bacteria,1UF2S@1239|Firmicutes,4HDR8@91061|Bacilli,1ZCK7@1386|Bacillus 91061|Bacilli U AAA domain - - - ko:K02282 - - - - ko00000,ko02035,ko02044 - - - AAA_31,Response_reg k141_19090_2 796606.BMMGA3_01500 5.37e-269 743.0 COG4962@1|root,COG4962@2|Bacteria,1TQ0Z@1239|Firmicutes,4HAQM@91061|Bacilli,1ZBDR@1386|Bacillus 91061|Bacilli U COG4962 Flp pilus assembly protein, ATPase CpaF cpaF - - ko:K02283 - - - - ko00000,ko02035,ko02044 - - - T2SSE k141_20266_1 218284.CCDN010000006_gene3726 3.85e-105 322.0 COG0768@1|root,COG0768@2|Bacteria,1TQHY@1239|Firmicutes,4H9MT@91061|Bacilli,1ZAX9@1386|Bacillus 91061|Bacilli M Penicillin-binding Protein pbpC - 3.4.16.4 ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 M00625 - - ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 - - - MecA_N,PBP_dimer,Transpeptidase k141_6032_1 485915.Dret_1485 1.2e-12 67.8 COG0686@1|root,COG0686@2|Bacteria,1QTX1@1224|Proteobacteria,42MSF@68525|delta/epsilon subdivisions,2WKJ5@28221|Deltaproteobacteria,2M87G@213115|Desulfovibrionales 28221|Deltaproteobacteria C Belongs to the AlaDH PNT family ald - 1.4.1.1 ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 - R00396 RC00008 ko00000,ko00001,ko01000 - - iAF987.Gmet_1099 AlaDh_PNT_C,AlaDh_PNT_N k141_6032_2 867903.ThesuDRAFT_00225 1.39e-49 163.0 COG0756@1|root,COG0756@2|Bacteria,1V6HX@1239|Firmicutes,24K3X@186801|Clostridia,3WD66@538999|Clostridiales incertae sedis 186801|Clostridia F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA dut - 3.6.1.23 ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00053 R02100,R11896 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 - - - dUTPase k141_7213_1 223926.28807182 7.86e-175 490.0 COG0777@1|root,COG0777@2|Bacteria,1MW8G@1224|Proteobacteria,1RNDS@1236|Gammaproteobacteria,1XUF4@135623|Vibrionales 135623|Vibrionales I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA accD GO:0003674,GO:0003824,GO:0003989,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009317,GO:0009987,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0019752,GO:0032787,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576,GO:1902494 2.1.3.15,6.4.1.2 ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans k141_25034_1 218284.CCDN010000001_gene763 3.12e-165 468.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HAWZ@91061|Bacilli,1ZCGC@1386|Bacillus 91061|Bacilli I acyl-CoA dehydrogenase yngJ - 1.3.8.1 ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 - R01175,R01178,R02661,R03172,R04751 RC00052,RC00068,RC00076,RC00120,RC00148 ko00000,ko00001,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_21527_1 1116375.VEJY3_13850 4.18e-115 339.0 COG0457@1|root,COG0457@2|Bacteria,1N260@1224|Proteobacteria,1S9QX@1236|Gammaproteobacteria,1XSRE@135623|Vibrionales 135623|Vibrionales S MSHA biogenesis protein MshN mshN - - ko:K12284 - - - - ko00000,ko02044 - - - TPR_16,TPR_19 k141_21527_2 223926.28807711 0.0 975.0 COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,1XSQP@135623|Vibrionales 135623|Vibrionales NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB mshE - - ko:K12276 ko05111,map05111 - - - ko00000,ko00001,ko02044 - - - T2SSE,T2SSE_N k141_21527_3 1280001.BAOA01000048_gene1825 3.08e-29 114.0 COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RQMI@1236|Gammaproteobacteria,1XSK4@135623|Vibrionales 135623|Vibrionales NU MSHA biogenesis protein MshG mshG - - ko:K12278 - - - - ko00000,ko02044 - - - T2SSF k141_27405_1 1196031.ALEG01000064_gene3551 7.58e-13 68.6 COG4980@1|root,COG4980@2|Bacteria,1VFY7@1239|Firmicutes,4HNWV@91061|Bacilli,1ZEKS@1386|Bacillus 91061|Bacilli S COG4980 Gas vesicle protein ytxH - - - - - - - - - - - YtxH k141_33377_1 1294265.JCM21738_618 5.22e-86 259.0 COG1530@1|root,COG1530@2|Bacteria,1TQS4@1239|Firmicutes,4HC3Q@91061|Bacilli,1ZCCF@1386|Bacillus 91061|Bacilli J ribonuclease, Rne Rng family rng - - ko:K08301 - - - - ko00000,ko01000,ko03009,ko03019 - - - RNase_E_G,S1 k141_15576_3 218284.CCDN010000006_gene3653 8.75e-44 152.0 COG3595@1|root,COG3595@2|Bacteria,1TS90@1239|Firmicutes,4HDI6@91061|Bacilli,1ZC95@1386|Bacillus 91061|Bacilli S Putative adhesin yvlB - - - - - - - - - - - DUF4097 k141_14380_1 547228.M5AC25_9CAUD 1.86e-27 106.0 4QANR@10239|Viruses,4QV6N@35237|dsDNA viruses no RNA stage,4QPG3@28883|Caudovirales,4QKUG@10699|Siphoviridae 10699|Siphoviridae S Replication-relaxation - - - - - - - - - - - - - k141_19107_2 1453503.AU05_10685 3.68e-29 109.0 COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,1RQ4B@1236|Gammaproteobacteria,1YE1X@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03470 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_HII k141_28657_1 1078085.HMPREF1210_02966 1.32e-69 222.0 COG2837@1|root,COG2837@2|Bacteria,1UY9Y@1239|Firmicutes,4HACQ@91061|Bacilli,26ES5@186818|Planococcaceae 91061|Bacilli P Dyp-type peroxidase family ywbN GO:0005575,GO:0005576 - ko:K07223,ko:K16301 - - - - ko00000,ko01000,ko02000 2.A.108.2.3 - iYO844.BSU38260 Dyp_perox,TAT_signal k141_28657_2 1307436.PBF_05768 4.04e-16 79.7 COG0672@1|root,COG0672@2|Bacteria,1TQIA@1239|Firmicutes,4HCJZ@91061|Bacilli,1ZDYA@1386|Bacillus 91061|Bacilli P COG0672 High-affinity Fe2 Pb2 permease ywbL - - ko:K07243 - - - - ko00000,ko02000 2.A.108.1,2.A.108.2 - - FTR1 k141_7214_1 171693.BN988_03363 5.89e-66 217.0 COG0075@1|root,COG3916@1|root,COG0075@2|Bacteria,COG3916@2|Bacteria,1TR3I@1239|Firmicutes,4HA6W@91061|Bacilli 91061|Bacilli E Aminotransferase class-V - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10,Acetyltransf_5,Acetyltransf_9,Aminotran_5 k141_20274_2 1246484.D479_09165 1.61e-91 271.0 COG0563@1|root,COG0563@2|Bacteria,1TP27@1239|Firmicutes,4HA89@91061|Bacilli,3NDE9@45667|Halobacillus 91061|Bacilli F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism adk GO:0003674,GO:0003824,GO:0004017,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ADK,ADK_lid k141_29803_1 1196031.ALEG01000067_gene4752 1.78e-75 251.0 COG2866@1|root,COG2866@2|Bacteria,1TSF6@1239|Firmicutes,4HDT5@91061|Bacilli,1ZBGR@1386|Bacillus 91061|Bacilli E Zinc carboxypeptidase - - - - - - - - - - - - Peptidase_M14 k141_21528_2 1453501.JELR01000002_gene617 1.34e-10 61.6 COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,1RQQV@1236|Gammaproteobacteria,46448@72275|Alteromonadaceae 1236|Gammaproteobacteria MU COG1538 Outer membrane protein tolC - - ko:K12340 ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133 M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko02044 1.B.17,2.A.6.2 - - OEP k141_16721_1 1449126.JQKL01000002_gene1548 1.77e-25 104.0 COG2048@1|root,COG2048@2|Bacteria,1U4JW@1239|Firmicutes,24J6T@186801|Clostridia 186801|Clostridia C Cysteine-rich domain - - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 ko:K03389 ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200 M00356,M00357,M00563,M00567 R04540,R11928,R11931,R11943,R11944 RC00011 ko00000,ko00001,ko00002,ko01000 - - - CCG k141_16721_2 1379281.AVAG01000002_gene223 4.75e-12 65.9 COG1148@1|root,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria 2|Bacteria C 4Fe-4S ferredoxin iron-sulfur binding domain protein - - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 ko:K03388 ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200 M00356,M00357,M00563,M00567 R04540,R11928,R11931,R11943,R11944 RC00011 ko00000,ko00001,ko00002,ko01000 - - - FAD_oxidored,Fer4,Fer4_7,FlpD,Pyr_redox_2 k141_25035_1 665959.HMPREF1013_03789 7.19e-62 198.0 COG4989@1|root,COG4989@2|Bacteria,1TQ12@1239|Firmicutes,4HA57@91061|Bacilli,1ZD8D@1386|Bacillus 91061|Bacilli S Oxidoreductase ycsN - - - - - - - - - - - Aldo_ket_red k141_17968_1 796606.BMMGA3_11310 3.74e-16 81.6 COG1884@1|root,COG1884@2|Bacteria,1TSVA@1239|Firmicutes,4HDE1@91061|Bacilli,1ZAVR@1386|Bacillus 91061|Bacilli I COG1884 Methylmalonyl-CoA mutase, N-terminal domain subunit mutA - 5.4.99.2 ko:K01847 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00373,M00376,M00741 R00833 RC00395 ko00000,ko00001,ko00002,ko01000 - - - MM_CoA_mutase k141_15577_1 218284.CCDN010000012_gene4443 7.05e-88 261.0 COG1335@1|root,COG1335@2|Bacteria,1V2DX@1239|Firmicutes,4HJMV@91061|Bacilli,1ZGBB@1386|Bacillus 91061|Bacilli Q Isochorismatase family yaaI - - - - - - - - - - - Isochorismatase k141_19108_1 1294265.JCM21738_3034 7.16e-95 298.0 COG3973@1|root,COG3973@2|Bacteria,1TP39@1239|Firmicutes,4H9Y5@91061|Bacilli,1ZAWP@1386|Bacillus 91061|Bacilli L DNA helicase helD - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_19,UvrD-helicase,UvrD_C,UvrD_C_2 k141_22695_1 1462527.CCDM010000005_gene4783 1.95e-09 57.0 COG0247@1|root,COG0247@2|Bacteria,1TPFC@1239|Firmicutes,4HAKC@91061|Bacilli,23IYV@182709|Oceanobacillus 91061|Bacilli C Cysteine-rich domain lutA - - ko:K18928 - - - - ko00000 - - - CCG k141_22695_2 1294265.JCM21738_2333 2.48e-131 375.0 COG2186@1|root,COG2186@2|Bacteria,1V2TU@1239|Firmicutes,4HDHI@91061|Bacilli,1ZD1T@1386|Bacillus 91061|Bacilli K COG2186 Transcriptional regulators yvfI - - ko:K05799 - - - - ko00000,ko03000 - - - FCD,GntR k141_3678_1 218284.CCDN010000001_gene706 1.03e-221 615.0 COG0626@1|root,COG0626@2|Bacteria,1TPC7@1239|Firmicutes,4HAFQ@91061|Bacilli,1ZAR9@1386|Bacillus 91061|Bacilli E cystathionine mccB GO:0000096,GO:0000098,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008284,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019752,GO:0042127,GO:0043418,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0048518,GO:0048522,GO:0050667,GO:0050789,GO:0050794,GO:0065007,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 4.4.1.1,4.4.1.2,4.4.1.8 ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017,M00609 R00782,R01001,R01283,R01286,R02408,R04941 RC00056,RC00069,RC00348,RC00382,RC00487,RC00488,RC00710,RC01245,RC02303,RC02814 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU27250 Cys_Met_Meta_PP k141_7215_1 997296.PB1_14079 7.34e-40 142.0 COG0240@1|root,COG0240@2|Bacteria,1TQ5P@1239|Firmicutes,4HAXW@91061|Bacilli,1ZCHQ@1386|Bacillus 91061|Bacilli I Glycerol-3-phosphate dehydrogenase gpsA GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0047952,GO:0055114 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 - R00842,R00844 RC00029 ko00000,ko00001,ko01000 - - - NAD_Gly3P_dh_C,NAD_Gly3P_dh_N k141_10769_2 218284.CCDN010000001_gene1058 6.58e-108 312.0 COG0700@1|root,COG0700@2|Bacteria,1V45M@1239|Firmicutes,4HH1Y@91061|Bacilli,1ZFIY@1386|Bacillus 91061|Bacilli S Spore maturation protein spmB - - ko:K06374 - - - - ko00000 - - - Gate k141_10769_3 218284.CCDN010000001_gene1057 1.39e-124 356.0 COG2715@1|root,COG2715@2|Bacteria,1V1E2@1239|Firmicutes,4HBTK@91061|Bacilli,1ZBSV@1386|Bacillus 91061|Bacilli S Spore maturation protein spmA - - ko:K06373 - - - - ko00000 - - - Gate k141_32168_1 674977.VMC_18140 1.09e-161 456.0 COG4137@1|root,COG4137@2|Bacteria,1R3YD@1224|Proteobacteria,1RPUQ@1236|Gammaproteobacteria,1XSTU@135623|Vibrionales 135623|Vibrionales S transport system, permease component ypjD - - - - - - - - - - - Cytochrom_C_asm k141_32168_2 1219076.N646_1627 1.57e-287 790.0 COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,1RMU9@1236|Gammaproteobacteria,1XTFD@135623|Vibrionales 135623|Vibrionales U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components ffh - 3.6.5.4 ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko01000,ko02044 3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9 - - SRP54,SRP54_N,SRP_SPB k141_32168_3 1116375.VEJY3_13355 1.13e-289 791.0 COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,1RPEY@1236|Gammaproteobacteria,1XSKJ@135623|Vibrionales 135623|Vibrionales C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family serA - 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C,ACT k141_32168_4 1116375.VEJY3_13350 5.05e-151 425.0 COG0120@1|root,COG0120@2|Bacteria,1MVGR@1224|Proteobacteria,1RNF8@1236|Gammaproteobacteria,1XSM7@135623|Vibrionales 135623|Vibrionales G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate rpiA GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 5.3.1.6 ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167,M00580 R01056 RC00434 ko00000,ko00001,ko00002,ko01000 - - - Rib_5-P_isom_A k141_32168_5 1116375.VEJY3_13345 6.24e-137 387.0 COG0212@1|root,COG0212@2|Bacteria,1MZG0@1224|Proteobacteria,1S612@1236|Gammaproteobacteria,1XT1H@135623|Vibrionales 135623|Vibrionales H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family ygfA - 6.3.3.2 ko:K01934 ko00670,ko01100,map00670,map01100 - R02301 RC00183 ko00000,ko00001,ko01000 - - - 5-FTHF_cyc-lig k141_32168_6 1219076.N646_1680 3.41e-59 183.0 COG3027@1|root,COG3027@2|Bacteria,1NJEZ@1224|Proteobacteria,1SAG6@1236|Gammaproteobacteria,1XYD2@135623|Vibrionales 135623|Vibrionales D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division zapA - - ko:K09888 - - - - ko00000,ko03036 - - - ZapA k141_32168_7 1280001.BAOA01000068_gene2672 1.43e-120 346.0 COG3079@1|root,COG3079@2|Bacteria,1N7W0@1224|Proteobacteria,1SCPW@1236|Gammaproteobacteria,1XT2F@135623|Vibrionales 135623|Vibrionales S Belongs to the UPF0149 family VV2847 - - ko:K09895 - - - - ko00000 - - - UPF0149 k141_32168_8 1116375.VEJY3_13330 2.23e-155 444.0 COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,1RMS3@1236|Gammaproteobacteria,1XTCE@135623|Vibrionales 135623|Vibrionales CH COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases ubiH - - ko:K03185 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04989,R08773 RC02670 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_3 k141_4867_2 1121091.AUMP01000006_gene4229 2.32e-11 64.3 28IH1@1|root,2Z8IC@2|Bacteria,1TSE5@1239|Firmicutes,4HD81@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF4003) yeaA - - - - - - - - - - - DUF4003 k141_34581_1 42565.FP66_11215 2.88e-220 615.0 COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,1RMIW@1236|Gammaproteobacteria,1XI2S@135619|Oceanospirillales 135619|Oceanospirillales J Involved in the processing of the 5'end of 16S rRNA - - - ko:K08301 - - - - ko00000,ko01000,ko03009,ko03019 - - - RNase_E_G,S1 k141_22696_1 218284.CCDN010000002_gene2113 9.32e-13 68.2 COG0179@1|root,COG0179@2|Bacteria,1UY98@1239|Firmicutes,4HC89@91061|Bacilli,1ZCD1@1386|Bacillus 91061|Bacilli Q Fumarylacetoacetate (FAA) hydrolase family - - 3.7.1.2 ko:K16171 ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120 M00044 R01364 RC00326,RC00446 ko00000,ko00001,ko00002,ko01000 - - - FAA_hydrolase k141_15578_2 1280001.BAOA01000075_gene3238 5.73e-16 73.2 2E01C@1|root,32VQM@2|Bacteria,1N20N@1224|Proteobacteria,1SACC@1236|Gammaproteobacteria,1XTFG@135623|Vibrionales 135623|Vibrionales S YcxB-like protein VPA0798 - - - - - - - - - - - YcxB k141_27407_1 218284.CCDN010000002_gene2237 9.9e-112 336.0 COG3275@1|root,COG3275@2|Bacteria,1VTXF@1239|Firmicutes,4H9Z1@91061|Bacilli,1ZBKQ@1386|Bacillus 91061|Bacilli T Histidine kinase lytS - 2.7.13.3 ko:K07704 ko02020,map02020 M00492 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - 5TM-5TMR_LYT,GAF_3,HATPase_c,His_kinase k141_21530_1 315750.BPUM_3360 2.05e-101 308.0 COG0504@1|root,COG0504@2|Bacteria,1TP34@1239|Firmicutes,4H9X6@91061|Bacilli,1ZB0S@1386|Bacillus 91061|Bacilli F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates pyrG - 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 - - - CTP_synth_N,GATase k141_21530_2 1294265.JCM21738_3480 4.38e-36 130.0 COG3343@1|root,COG3343@2|Bacteria,1V6WX@1239|Firmicutes,4HIUK@91061|Bacilli,1ZH95@1386|Bacillus 91061|Bacilli K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling rpoE GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 - ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 - - - HARE-HTH k141_17969_1 1294265.JCM21738_3580 4.6e-43 146.0 2E4U1@1|root,32ZND@2|Bacteria,1VJ5M@1239|Firmicutes,4HQWX@91061|Bacilli,1ZN4P@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - DUF4234 k141_17969_2 997296.PB1_05722 6.25e-41 139.0 2DQU9@1|root,338QD@2|Bacteria,1VG1Q@1239|Firmicutes,4HQS2@91061|Bacilli,1ZKU6@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_13210_1 1453501.JELR01000001_gene1832 2.17e-257 748.0 COG3170@1|root,COG3170@2|Bacteria,1MXV7@1224|Proteobacteria,1RMM5@1236|Gammaproteobacteria,4646P@72275|Alteromonadaceae 1236|Gammaproteobacteria NU COG3170 Tfp pilus assembly protein FimV fimV - - ko:K08086 - - - - ko00000 - - - LysM,TPR_19 k141_26279_1 1453501.JELR01000002_gene848 1.69e-127 388.0 COG4225@1|root,COG4225@2|Bacteria,1MU2J@1224|Proteobacteria,1RR65@1236|Gammaproteobacteria,4660R@72275|Alteromonadaceae 1236|Gammaproteobacteria S unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins - - - - - - - - - - - - DUF4861,Glyco_hydro_88 k141_33378_1 1218108.KB908297_gene2911 2.61e-06 55.5 COG1073@1|root,COG1073@2|Bacteria,4NMZQ@976|Bacteroidetes,1I1MU@117743|Flavobacteriia 976|Bacteroidetes S Alpha beta hydrolase - - - - - - - - - - - - Abhydrolase_1,Hydrolase_4 k141_25037_2 1453503.AU05_16970 1.02e-31 124.0 COG4714@1|root,COG4714@2|Bacteria,1N40I@1224|Proteobacteria,1S1R3@1236|Gammaproteobacteria,1YIGG@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S Protein of unknown function (DUF2167) - - - - - - - - - - - - DUF2167 k141_21531_1 1042377.AFPJ01000012_gene1392 1.05e-78 241.0 COG1266@1|root,COG1266@2|Bacteria 2|Bacteria V CAAX protease self-immunity - - - ko:K07052 - - - - ko00000 - - - Abi k141_8457_1 674977.VMC_02520 4.62e-85 253.0 COG3078@1|root,COG3078@2|Bacteria,1N8HM@1224|Proteobacteria,1SDUG@1236|Gammaproteobacteria,1XWXD@135623|Vibrionales 135623|Vibrionales S A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis yihI - - ko:K09894 - - - - ko00000 - - - YihI k141_8457_2 1280001.BAOA01000051_gene1539 2.16e-95 280.0 2E8BZ@1|root,332QM@2|Bacteria,1NAZY@1224|Proteobacteria,1SD7I@1236|Gammaproteobacteria,1XWXQ@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF2489) HD1705 - - - - - - - - - - - DUF2489 k141_8457_3 1116375.VEJY3_00520 0.0 894.0 COG0635@1|root,COG0635@2|Bacteria,1MV1I@1224|Proteobacteria,1RN1Y@1236|Gammaproteobacteria,1XT7M@135623|Vibrionales 135623|Vibrionales H Belongs to the anaerobic coproporphyrinogen-III oxidase family hemN - 1.3.98.3 ko:K02495 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R06895 RC00884 ko00000,ko00001,ko00002,ko01000 - - - HemN_C,Radical_SAM k141_8457_4 223926.28805098 1.91e-158 449.0 COG1816@1|root,COG1816@2|Bacteria,1MWBV@1224|Proteobacteria,1RNVI@1236|Gammaproteobacteria,1XU9B@135623|Vibrionales 135623|Vibrionales F COG1816 Adenosine deaminase add GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009119,GO:0009163,GO:0009164,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659 3.5.4.4 ko:K01488 ko00230,ko01100,ko05340,map00230,map01100,map05340 - R01560,R02556 RC00477 ko00000,ko00001,ko01000 - - - A_deaminase k141_22697_1 1211814.CAPG01000105_gene4403 4.68e-11 58.5 2EG8N@1|root,33A0G@2|Bacteria,1VMHK@1239|Firmicutes,4HSIH@91061|Bacilli,1ZJWT@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_26280_1 283699.D172_0052 1.75e-73 234.0 COG2211@1|root,COG2211@2|Bacteria,1MVUM@1224|Proteobacteria,1RP5J@1236|Gammaproteobacteria,2Q49H@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria G MFS/sugar transport protein - - - ko:K03292 - - - - ko00000 2.A.2 - - MFS_2 k141_4868_1 1384054.N790_11390 4.27e-72 243.0 COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RN01@1236|Gammaproteobacteria,1X5AZ@135614|Xanthomonadales 135614|Xanthomonadales S MMPL family - - - - - - - - - - - - MMPL k141_129_2 1219076.N646_0129 3.73e-141 399.0 COG3318@1|root,COG3318@2|Bacteria,1N0JQ@1224|Proteobacteria,1SUIC@1236|Gammaproteobacteria,1XTR3@135623|Vibrionales 135623|Vibrionales S Belongs to the UPF0149 family - - - ko:K07039 - - - - ko00000 - - - UPF0149 k141_129_3 1116375.VEJY3_04970 7.94e-117 343.0 COG0754@1|root,COG0754@2|Bacteria,1MW6V@1224|Proteobacteria,1RQAP@1236|Gammaproteobacteria,1XTKG@135623|Vibrionales 135623|Vibrionales E Glutathionylspermidine synthase preATP-grasp - - - - - - - - - - - - GSP_synth k141_4869_1 1279017.AQYJ01000028_gene2321 1.27e-36 142.0 COG2982@1|root,COG2982@2|Bacteria,1MUME@1224|Proteobacteria,1RNPC@1236|Gammaproteobacteria,464KK@72275|Alteromonadaceae 1236|Gammaproteobacteria M Domain of Unknown Function (DUF748) - - - - - - - - - - - - DUF748,OmpA k141_32169_2 767817.Desgi_0095 7.84e-48 166.0 COG0313@1|root,COG0313@2|Bacteria,1TP6U@1239|Firmicutes,24864@186801|Clostridia,260K0@186807|Peptococcaceae 186801|Clostridia H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA rsmI - 2.1.1.198 ko:K07056 - - - - ko00000,ko01000,ko03009 - - - TP_methylase k141_14383_2 218284.CCDN010000001_gene947 5.35e-82 250.0 COG1752@1|root,COG1752@2|Bacteria,1TRJW@1239|Firmicutes,4HB8J@91061|Bacilli,1ZC13@1386|Bacillus 91061|Bacilli S esterase of the alpha-beta hydrolase superfamily yqhO GO:0003674,GO:0003824,GO:0016787 - ko:K07001 - - - - ko00000 - - - Patatin k141_15605_1 1279017.AQYJ01000027_gene1669 9.83e-85 268.0 COG0515@1|root,COG0631@1|root,COG0515@2|Bacteria,COG0631@2|Bacteria,1MV1P@1224|Proteobacteria,1RNQN@1236|Gammaproteobacteria,464NH@72275|Alteromonadaceae 1236|Gammaproteobacteria T Serine threonine protein - - 3.1.3.16 ko:K01090 - - - - ko00000,ko01000 - - - PP2C_2,Pkinase k141_10784_1 218284.CCDN010000001_gene1003 1.64e-117 348.0 COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,4HADJ@91061|Bacilli,1ZAZZ@1386|Bacillus 91061|Bacilli L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII dinB GO:0008150,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0050896 2.7.7.7 ko:K02346 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH k141_20289_1 1294265.JCM21738_3410 3.81e-116 343.0 COG0750@1|root,COG0750@2|Bacteria,1TPIR@1239|Firmicutes,4H9TW@91061|Bacilli,1ZB04@1386|Bacillus 91061|Bacilli M Stage IV sporulation protein B spoIVB - 3.4.21.116 ko:K06399 - - - - ko00000,ko01000,ko01002 - - - PDZ,PDZ_2,Peptidase_S55 k141_9610_1 1042377.AFPJ01000007_gene1876 1.49e-90 278.0 COG1463@1|root,COG1463@2|Bacteria,1MU4B@1224|Proteobacteria,1S5E8@1236|Gammaproteobacteria,46BX6@72275|Alteromonadaceae 1236|Gammaproteobacteria Q MlaD protein - - - ko:K02067 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaD k141_32177_1 1042377.AFPJ01000007_gene1776 6.64e-64 196.0 COG2127@1|root,COG2127@2|Bacteria,1MZU8@1224|Proteobacteria,1S8Z7@1236|Gammaproteobacteria,467VM@72275|Alteromonadaceae 1236|Gammaproteobacteria S Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation clpS GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0050896,GO:0051087 - ko:K06891 - - - - ko00000 - - - ClpS k141_21553_1 1034347.CAHJ01000062_gene1029 1.59e-101 304.0 COG0535@1|root,COG0535@2|Bacteria,1TR52@1239|Firmicutes,4HCPA@91061|Bacilli,1ZQDG@1386|Bacillus 91061|Bacilli C Elongator protein 3, MiaB family, Radical SAM - - - - - - - - - - - - Fer4_12,Radical_SAM,SPASM k141_28675_1 218284.CCDN010000007_gene3824 1.2e-85 268.0 COG0739@1|root,COG0739@2|Bacteria,1TRWJ@1239|Firmicutes,4HB43@91061|Bacilli,1ZBXH@1386|Bacillus 91061|Bacilli M G5 nlpD - - - - - - - - - - - G5,LysM,Peptidase_M23 k141_15606_1 218284.CCDN010000008_gene4137 1.81e-120 365.0 COG0058@1|root,COG0058@2|Bacteria,1TQAJ@1239|Firmicutes,4H9XI@91061|Bacilli,1ZCRF@1386|Bacillus 91061|Bacilli G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties glgP GO:0000272,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005976,GO:0005977,GO:0005980,GO:0006073,GO:0006091,GO:0006112,GO:0008144,GO:0008150,GO:0008152,GO:0008184,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0015980,GO:0016052,GO:0016740,GO:0016757,GO:0016758,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901575 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 - R02111 - ko00000,ko00001,ko01000 - GT35 iYO844.BSU30940 Phosphorylase k141_7228_1 1196031.ALEG01000011_gene5192 2e-108 326.0 COG3634@1|root,COG3634@2|Bacteria,1TPYN@1239|Firmicutes,4H9W1@91061|Bacilli,1ZCRN@1386|Bacillus 91061|Bacilli O Alkyl hydroperoxide reductase ahpF - - ko:K03387 - - - - ko00000,ko01000 - - - Pyr_redox_2,Thioredoxin_3 k141_22717_1 1279017.AQYJ01000028_gene2065 1.28e-59 191.0 COG5523@1|root,COG5523@2|Bacteria,1N48D@1224|Proteobacteria,1T4Q1@1236|Gammaproteobacteria,46DEE@72275|Alteromonadaceae 1236|Gammaproteobacteria S integral membrane protein - - - - - - - - - - - - - k141_22717_2 1279017.AQYJ01000028_gene2064 1.65e-100 299.0 COG1714@1|root,COG1714@2|Bacteria,1RIE9@1224|Proteobacteria,1S566@1236|Gammaproteobacteria,467PA@72275|Alteromonadaceae 1236|Gammaproteobacteria S RDD family - - - - - - - - - - - - RDD k141_11419_1 1499680.CCFE01000024_gene2828 1.13e-54 180.0 COG1496@1|root,COG1496@2|Bacteria,1TS34@1239|Firmicutes,4HFUM@91061|Bacilli,1ZBZZ@1386|Bacillus 91061|Bacilli S Belongs to the multicopper oxidase YfiH RL5 family ylmD GO:0003674,GO:0005488,GO:0005507,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - ko:K05810 - - - - ko00000,ko01000 - - - Cu-oxidase_4 k141_4195_1 218284.CCDN010000007_gene3965 4.66e-120 356.0 COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,4H9VK@91061|Bacilli,1ZB07@1386|Bacillus 91061|Bacilli G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system - - 3.6.3.17 ko:K02056 - M00221 - - ko00000,ko00002,ko01000,ko02000 3.A.1.2 - - ABC_tran k141_4195_2 218284.CCDN010000007_gene3966 6.27e-23 95.1 COG1172@1|root,COG1172@2|Bacteria,1TP72@1239|Firmicutes,4HBU9@91061|Bacilli,1ZQAD@1386|Bacillus 91061|Bacilli G Belongs to the binding-protein-dependent transport system permease family rbsC3 - - ko:K02057 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - BPD_transp_2 k141_18532_1 42565.FP66_09465 3.69e-77 238.0 COG3317@1|root,COG3317@2|Bacteria,1N670@1224|Proteobacteria,1S56T@1236|Gammaproteobacteria,1XM9F@135619|Oceanospirillales 135619|Oceanospirillales M NlpB/DapX lipoprotein - - - - - - - - - - - - Lipoprotein_18 k141_18532_2 42565.FP66_09470 3.73e-66 207.0 COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,1RNH9@1236|Gammaproteobacteria,1XHES@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) dapA - 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS k141_36140_1 935837.JAEK01000007_gene3266 1.63e-111 333.0 COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,4H9SB@91061|Bacilli,1ZBAN@1386|Bacillus 91061|Bacilli S COG1253 Hemolysins and related proteins containing CBS domains yrkA - - - - - - - - - - - CBS,CorC_HlyC,DUF21 k141_25689_1 1453501.JELR01000001_gene2168 8.07e-60 199.0 COG0845@1|root,COG0845@2|Bacteria,1PEVY@1224|Proteobacteria,1RPEQ@1236|Gammaproteobacteria,466EU@72275|Alteromonadaceae 1236|Gammaproteobacteria M Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - - - - - - - - - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 k141_35132_1 218284.CCDN010000007_gene3989 1.13e-84 261.0 COG0112@1|root,COG0112@2|Bacteria,1TQVM@1239|Firmicutes,4HA5K@91061|Bacilli,1ZB9V@1386|Bacillus 91061|Bacilli E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism glyA - 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 - - - SHMT k141_26990_1 380394.Lferr_1493 2.45e-98 312.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,1RP3T@1236|Gammaproteobacteria,2NC9Q@225057|Acidithiobacillales 225057|Acidithiobacillales H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate - - 2.7.9.2 ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 M00173,M00374 R00199 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - PEP-utilizers,PEP-utilizers_C,PPDK_N k141_26990_2 1415630.U771_16895 8.48e-48 161.0 COG0454@1|root,COG0454@2|Bacteria 2|Bacteria K -acetyltransferase - - 2.3.1.82 ko:K03830,ko:K18816 - - - - br01600,ko00000,ko01000,ko01504 - - - Acetyltransf_1,Acetyltransf_10,Acetyltransf_4 k141_26990_3 1279017.AQYJ01000025_gene478 9.27e-187 529.0 COG0479@1|root,COG0479@2|Bacteria,1QVWG@1224|Proteobacteria,1RNMQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria C 4Fe-4S dicluster domain asrA - - ko:K16950 ko00920,ko01120,map00920,map01120 - R00858,R10146 RC00065 ko00000,ko00001 - - - Fer4_22 k141_26990_4 314278.NB231_04680 1.15e-43 148.0 COG0664@1|root,COG0664@2|Bacteria,1RII7@1224|Proteobacteria,1S7IH@1236|Gammaproteobacteria 1236|Gammaproteobacteria T COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - - - - - - - - - - cNMP_binding k141_26990_5 395961.Cyan7425_2662 8.35e-09 56.6 COG0543@1|root,COG0543@2|Bacteria 2|Bacteria C 2 iron, 2 sulfur cluster binding asrB - - ko:K02823 ko00240,ko01100,map00240,map01100 - - - ko00000,ko00001 - - - DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1 k141_29096_2 401053.AciPR4_2485 4.53e-22 89.0 COG0713@1|root,COG0713@2|Bacteria,3Y4XI@57723|Acidobacteria,2JJIM@204432|Acidobacteriia 204432|Acidobacteriia C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoK - 1.6.5.3 ko:K00340 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q2 k141_14811_2 1279017.AQYJ01000026_gene192 3.38e-114 333.0 COG0283@1|root,COG0283@2|Bacteria,1MUUD@1224|Proteobacteria,1RNKT@1236|Gammaproteobacteria,466NJ@72275|Alteromonadaceae 1236|Gammaproteobacteria F Belongs to the cytidylate kinase family. Type 1 subfamily cmk GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0015939,GO:0015940,GO:0015949,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 ko:K00945 ko00240,ko01100,map00240,map01100 M00052 R00158,R00512,R01665 RC00002 ko00000,ko00001,ko00002,ko01000 - - iPC815.YPO1391,iSDY_1059.SDY_2348 Cytidylate_kin k141_14811_3 1453501.JELR01000001_gene2053 0.0 1207.0 COG0128@1|root,COG0287@1|root,COG0128@2|Bacteria,COG0287@2|Bacteria,1MWMK@1224|Proteobacteria,1RQ8U@1236|Gammaproteobacteria,46511@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate aroA - 1.3.1.12,1.3.1.43,2.5.1.19 ko:K00210,ko:K00220,ko:K00800 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00022,M00025,M00040 R00732,R01728,R03460 RC00125,RC00350 ko00000,ko00001,ko00002,ko01000 - - - EPSP_synthase,PDH k141_14811_4 1042377.AFPJ01000019_gene2501 4.66e-226 627.0 COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,1MU60@1224|Proteobacteria,1RNRD@1236|Gammaproteobacteria,464UF@72275|Alteromonadaceae 1236|Gammaproteobacteria E chorismate mutase pheA - 4.2.1.51,5.4.99.5 ko:K04518,ko:K14170 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024,M00025 R00691,R01373,R01715 RC00360,RC03116 ko00000,ko00001,ko00002,ko01000 - - - ACT,CM_2,PDT k141_14811_5 1453501.JELR01000001_gene2051 7.68e-221 613.0 COG1932@1|root,COG1932@2|Bacteria,1MUB5@1224|Proteobacteria,1RMKU@1236|Gammaproteobacteria,465ZM@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine serC GO:0003674,GO:0003824,GO:0004648,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006520,GO:0006553,GO:0006563,GO:0006564,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009085,GO:0009089,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019752,GO:0019842,GO:0030170,GO:0033359,GO:0034641,GO:0036094,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046394,GO:0046451,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901615,GO:1901617 2.6.1.52 ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 M00020,M00124 R04173,R05085 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - iEcE24377_1341.EcE24377A_1004,iPC815.YPO1389,iYL1228.KPN_00935 Aminotran_5 k141_14811_6 1453501.JELR01000001_gene2050 5.7e-23 97.4 COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,1RN03@1236|Gammaproteobacteria,4643E@72275|Alteromonadaceae 1236|Gammaproteobacteria L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrA GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0018130,GO:0019438,GO:0032774,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042493,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097659,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 5.99.1.3 ko:K02469 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseA_C,DNA_topoisoIV k141_24367_1 1048834.TC41_1598 2.38e-49 172.0 COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,4HAJ6@91061|Bacilli,278SV@186823|Alicyclobacillaceae 91061|Bacilli S GTPase that plays an essential role in the late steps of ribosome biogenesis der - - ko:K03977 - - - - ko00000,ko03009 - - - KH_dom-like,MMR_HSR1 k141_12692_1 215803.DB30_6026 1.84e-06 50.1 COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,42MRR@68525|delta/epsilon subdivisions,2WIQ7@28221|Deltaproteobacteria,2YTZJ@29|Myxococcales 28221|Deltaproteobacteria L that it carries out the mismatch recognition step. This protein has a weak ATPase activity mutS GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K03555 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V k141_12692_2 1267533.KB906738_gene2107 1.61e-18 87.0 COG1472@1|root,COG1472@2|Bacteria,3Y32Y@57723|Acidobacteria,2JIFE@204432|Acidobacteriia 204432|Acidobacteriia G Glycosyl hydrolase family 3 N terminal domain - - 3.2.1.52 ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 M00628 R00022,R05963,R07809,R07810,R10831 RC00049 ko00000,ko00001,ko00002,ko01000 - - - Glyco_hydro_3 k141_20749_1 1279017.AQYJ01000028_gene2455 1.55e-21 92.4 COG3329@1|root,COG3329@2|Bacteria,1N85P@1224|Proteobacteria,1RRX7@1236|Gammaproteobacteria,4665S@72275|Alteromonadaceae 1236|Gammaproteobacteria S Na+-dependent bicarbonate transporter superfamily - - - ko:K07086 - - - - ko00000 - - - Sbt_1 k141_31382_1 218284.CCDN010000002_gene2398 2.08e-109 319.0 COG0664@1|root,COG0664@2|Bacteria,1UEKS@1239|Firmicutes,4HCZE@91061|Bacilli,1ZRQ9@1386|Bacillus 91061|Bacilli K Cyclic nucleotide-monophosphate binding domain fnr5 - - - - - - - - - - - HTH_Crp_2,cNMP_binding k141_17226_1 1353531.AZNX01000033_gene4067 3.78e-08 54.7 COG2197@1|root,COG2197@2|Bacteria,1RGH6@1224|Proteobacteria,2U81B@28211|Alphaproteobacteria,4BM6D@82115|Rhizobiaceae 28211|Alphaproteobacteria T helix_turn_helix, Lux Regulon - - - ko:K02479,ko:K07684 ko02020,map02020 M00471 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg k141_17226_2 218284.CCDN010000001_gene1910 2.31e-67 211.0 COG0455@1|root,COG0455@2|Bacteria,1TRZ5@1239|Firmicutes,4HCWZ@91061|Bacilli,1ZE3G@1386|Bacillus 91061|Bacilli D Belongs to the ParA family ylxH - - ko:K04562 - - - - ko00000,ko02035 - - - AAA_31,CbiA,ParA k141_36165_1 666509.RCA23_c12630 7.23e-68 209.0 COG2801@1|root,COG2801@2|Bacteria,1MVN5@1224|Proteobacteria,2TQK0@28211|Alphaproteobacteria 28211|Alphaproteobacteria L COG2801 Transposase and inactivated derivatives - - - - - - - - - - - - HTH_21,rve_3 k141_16054_1 218284.CCDN010000001_gene442 1.99e-71 222.0 COG2267@1|root,COG2267@2|Bacteria,1UHRG@1239|Firmicutes,4IS7B@91061|Bacilli,1ZS1J@1386|Bacillus 91061|Bacilli I alpha/beta hydrolase fold - - 3.4.11.5 ko:K01259 ko00330,map00330 - R00135 - ko00000,ko00001,ko01000,ko01002 - - - Abhydrolase_1 k141_25713_1 1131730.BAVI_03284 3.3e-17 73.2 2E54C@1|root,32ZXB@2|Bacteria,1VJFQ@1239|Firmicutes,4HQN1@91061|Bacilli,1ZK01@1386|Bacillus 91061|Bacilli S Belongs to the SspP family sspP - - ko:K06433 - - - - ko00000 - - - SspP k141_25713_2 218284.CCDN010000001_gene1508 1.74e-40 135.0 2CNCH@1|root,32SGT@2|Bacteria,1VDMW@1239|Firmicutes,4HMYB@91061|Bacilli,1ZIW4@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_25713_3 768706.Desor_4857 0.000406 44.7 COG1921@1|root,COG1921@2|Bacteria,1TQT8@1239|Firmicutes,2498U@186801|Clostridia,2608U@186807|Peptococcaceae 186801|Clostridia J Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis selA - 2.9.1.1 ko:K01042 ko00450,ko00970,map00450,map00970 - R08219 RC01246 ko00000,ko00001,ko01000 - - - Se-cys_synth_N,SelA k141_29097_1 218284.CCDN010000002_gene2197 3.33e-100 307.0 COG5373@1|root,COG5373@2|Bacteria,1UXZY@1239|Firmicutes,4HEQP@91061|Bacilli,1ZBHN@1386|Bacillus 91061|Bacilli S Predicted membrane protein (DUF2339) - - - - - - - - - - - - DUF2339 k141_18568_1 1385511.N783_15670 3.11e-68 212.0 COG1335@1|root,COG1335@2|Bacteria,1V8ER@1239|Firmicutes,4HIZB@91061|Bacilli 91061|Bacilli Q Isochorismatase family phzA - - - - - - - - - - - Isochorismatase k141_18568_2 665959.HMPREF1013_03221 2.8e-05 45.4 2C2RW@1|root,32WKK@2|Bacteria,1VDHU@1239|Firmicutes,4HJU1@91061|Bacilli,1ZJ8T@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF4306) yjdJ - - - - - - - - - - - DUF4306 k141_7678_1 506534.Rhein_3327 9.45e-61 194.0 COG1247@1|root,COG1247@2|Bacteria,1RDHN@1224|Proteobacteria,1T03S@1236|Gammaproteobacteria 1236|Gammaproteobacteria M COG1247 Sortase and related - - 2.3.1.183 ko:K03823 ko00440,ko01130,map00440,map01130 - R08871,R08938 RC00004,RC00064 ko00000,ko00001,ko01000 - - - Acetyltransf_4 k141_19698_1 1121938.AUDY01000011_gene601 1.14e-139 410.0 COG2132@1|root,COG2132@2|Bacteria,1TQSU@1239|Firmicutes,4HDD6@91061|Bacilli 91061|Bacilli Q Multicopper cotA GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016679,GO:0016682,GO:0016722,GO:0052716,GO:0055114 1.16.3.3 ko:K06324 - - - - ko00000,ko01000 - - - Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3 k141_16055_1 218284.CCDN010000005_gene3229 7.95e-110 349.0 COG1074@1|root,COG1074@2|Bacteria,1TQ35@1239|Firmicutes,4HA64@91061|Bacilli,1ZBG6@1386|Bacillus 91061|Bacilli L ATP-dependent helicase nuclease subunit A addA GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 3.6.4.12 ko:K16898 - - - - ko00000,ko01000,ko03400 - - - PDDEXK_1,UvrD-helicase,UvrD_C k141_27778_1 1116375.VEJY3_01560 0.0 892.0 COG1178@1|root,COG1178@2|Bacteria,1MWCF@1224|Proteobacteria,1RNHK@1236|Gammaproteobacteria,1XT1Z@135623|Vibrionales 135623|Vibrionales P COG1178 ABC-type Fe3 transport system, permease component thiP - - ko:K02063 ko02010,map02010 M00191 - - ko00000,ko00001,ko00002,ko02000 3.A.1.19 - - BPD_transp_1 k141_27778_2 1116375.VEJY3_01555 6.18e-217 601.0 COG4143@1|root,COG4143@2|Bacteria,1MUBB@1224|Proteobacteria,1RMQ9@1236|Gammaproteobacteria,1XT2T@135623|Vibrionales 135623|Vibrionales P COG4143 ABC-type thiamine transport system, periplasmic component tbpA - - ko:K02064 ko02010,map02010 M00191 - - ko00000,ko00001,ko00002,ko02000 3.A.1.19 - - SBP_bac_1,SBP_bac_6 k141_27778_3 1116375.VEJY3_01550 1.06e-144 408.0 COG0163@1|root,COG0163@2|Bacteria,1RA0P@1224|Proteobacteria,1RPN1@1236|Gammaproteobacteria,1XSI5@135623|Vibrionales 135623|Vibrionales H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN ubiX GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008694,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.129 ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 M00117 R01238,R02952,R03367,R04985,R04986,R11225 RC00391,RC00814,RC03392 ko00000,ko00001,ko00002,ko01000 - - - Flavoprotein k141_27778_4 1116375.VEJY3_01545 0.0 901.0 COG0773@1|root,COG0773@2|Bacteria,1MUC5@1224|Proteobacteria,1RMMT@1236|Gammaproteobacteria,1XTVH@135623|Vibrionales 135623|Vibrionales M Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate mpl - 6.3.2.45 ko:K02558 - - - - ko00000,ko01000 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M k141_27778_5 223926.28805295 2.85e-38 136.0 COG0158@1|root,COG0158@2|Bacteria,1MW0E@1224|Proteobacteria,1RNFF@1236|Gammaproteobacteria,1XT96@135623|Vibrionales 135623|Vibrionales G Belongs to the FBPase class 1 family fbp GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0071704,GO:1901135,GO:1901576 3.1.3.11 ko:K03841 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910 M00003,M00165,M00167,M00344 R00762,R04780 RC00017 ko00000,ko00001,ko00002,ko01000,ko04147 - - - FBPase k141_31383_1 218284.CCDN010000007_gene3863 3.81e-64 198.0 COG0599@1|root,COG0599@2|Bacteria,1V78I@1239|Firmicutes,4HKFY@91061|Bacilli,1ZHVR@1386|Bacillus 91061|Bacilli S Carboxymuconolactone decarboxylase family - - 4.1.1.44 ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 - R03470 RC00938 ko00000,ko00001,ko01000 - - - CMD k141_18569_1 1294265.JCM21738_77 6.73e-75 228.0 COG0517@1|root,COG0517@2|Bacteria,1TR5G@1239|Firmicutes,4H9ZA@91061|Bacilli,1ZD7H@1386|Bacillus 91061|Bacilli S CBS domain - - - - - - - - - - - - CBS k141_13901_1 1274374.CBLK010000075_gene3637 5.07e-60 199.0 COG2603@1|root,COG2603@2|Bacteria,1TQ8T@1239|Firmicutes,4HBX4@91061|Bacilli,26UGA@186822|Paenibacillaceae 91061|Bacilli S tRNA 2-selenouridine synthase selU - - ko:K06917 - - - - ko00000,ko01000,ko03016 - - - Rhodanese k141_17229_1 1246484.D479_01932 2.49e-60 197.0 COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,4HG3V@91061|Bacilli,3NEIU@45667|Halobacillus 91061|Bacilli E ATPases associated with a variety of cellular activities - - 3.6.3.25,3.6.3.30 ko:K02010,ko:K02045 ko00920,ko02010,map00920,map02010 M00185,M00190 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.10,3.A.1.6.1,3.A.1.6.3 - - ABC_tran k141_32577_2 886293.Sinac_5243 8.6e-119 347.0 COG0115@1|root,COG0115@2|Bacteria,2J2GT@203682|Planctomycetes 203682|Planctomycetes H Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase - - 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_4 k141_23313_1 1294265.JCM21738_2341 6.54e-89 271.0 COG1171@1|root,COG1171@2|Bacteria,1TP22@1239|Firmicutes,4H9NK@91061|Bacilli,1ZBM0@1386|Bacillus 91061|Bacilli E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA - - 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - - ACT,ACT_4,PALP k141_23313_2 1294265.JCM21738_2340 1.71e-74 224.0 29Z93@1|root,30M77@2|Bacteria,1UAFH@1239|Firmicutes,4IKTW@91061|Bacilli,1ZHJH@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_36166_2 218284.CCDN010000001_gene550 8.73e-186 520.0 COG0016@1|root,COG0016@2|Bacteria,1TPFW@1239|Firmicutes,4HAVN@91061|Bacilli,1ZANR@1386|Bacillus 91061|Bacilli J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily pheS GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 ko:K01889 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Phe_tRNA-synt_N,tRNA-synt_2d k141_5491_1 595537.Varpa_4705 2.47e-67 213.0 COG4977@1|root,COG4977@2|Bacteria,1QTV9@1224|Proteobacteria,2W033@28216|Betaproteobacteria,4AK3B@80864|Comamonadaceae 28216|Betaproteobacteria K AraC-type transcriptional regulator N-terminus - - - - - - - - - - - - AraC_N,HTH_18 k141_24371_1 1294265.JCM21738_3622 2.19e-105 315.0 COG0477@1|root,COG2814@2|Bacteria,1TSR2@1239|Firmicutes,4HD8G@91061|Bacilli,1ZCGV@1386|Bacillus 91061|Bacilli EGP COG0477 Permeases of the major facilitator superfamily - - - - - - - - - - - - MFS_1,MFS_3 k141_6592_1 223926.28805480 2.73e-78 233.0 COG3445@1|root,COG3445@2|Bacteria,1RDRB@1224|Proteobacteria,1S45G@1236|Gammaproteobacteria,1XX0C@135623|Vibrionales 135623|Vibrionales S Acts as a radical domain for damaged PFL and possibly other radical proteins grcA GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006566,GO:0006567,GO:0006807,GO:0008150,GO:0008152,GO:0008861,GO:0009056,GO:0009063,GO:0009066,GO:0009068,GO:0009987,GO:0016054,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 - ko:K06866 - - - - ko00000 - - - Gly_radical k141_6592_2 223926.28805479 6.1e-293 801.0 COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,1RQ0H@1236|Gammaproteobacteria,1XT55@135623|Vibrionales 135623|Vibrionales E Threonine synthase thrC - 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 - - - PALP,Thr_synth_N k141_6592_3 945550.VISI1226_20091 5.61e-223 615.0 COG0083@1|root,COG0083@2|Bacteria,1MW8I@1224|Proteobacteria,1RMYR@1236|Gammaproteobacteria,1XU46@135623|Vibrionales 135623|Vibrionales F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate thrB GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.39 ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 M00018 R01771 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N k141_6592_4 1116375.VEJY3_02230 0.0 1558.0 COG0460@1|root,COG0527@1|root,COG0460@2|Bacteria,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,1RN1G@1236|Gammaproteobacteria,1XU62@135623|Vibrionales 135623|Vibrionales E Bifunctional aspartokinase I homoserine dehydrogenase I thrA - 1.1.1.3,2.7.2.4 ko:K12524 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00017,M00018,M00526,M00527 R00480,R01773,R01775 RC00002,RC00043,RC00087 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,ACT,ACT_7,Homoserine_dh,NAD_binding_3 k141_6592_5 1116375.VEJY3_02225 8.67e-99 288.0 28WAX@1|root,2ZIBD@2|Bacteria,1P4EX@1224|Proteobacteria,1SV3G@1236|Gammaproteobacteria,1XY5B@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_6592_6 223926.28805475 8.31e-108 311.0 COG0684@1|root,COG0684@2|Bacteria,1RH18@1224|Proteobacteria,1RS9U@1236|Gammaproteobacteria,1XX44@135623|Vibrionales 135623|Vibrionales H Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions - - - ko:K02553 - - - - ko00000,ko03019 - - - RraA-like k141_6592_7 1116375.VEJY3_02215 5.88e-68 208.0 2DRAF@1|root,33AYA@2|Bacteria,1NGMJ@1224|Proteobacteria,1SGEB@1236|Gammaproteobacteria,1XYBY@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF3293) - - - - - - - - - - - - DUF3293 k141_6592_8 1116375.VEJY3_02210 2.8e-167 468.0 COG0745@1|root,COG0745@2|Bacteria,1MWJG@1224|Proteobacteria,1RPU3@1236|Gammaproteobacteria,1XV50@135623|Vibrionales 135623|Vibrionales K COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain arcA - - ko:K07773 ko02020,ko02026,map02020,map02026 M00456 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C k141_6592_9 1116375.VEJY3_02205 5.23e-83 247.0 2AW44@1|root,31MZ1@2|Bacteria,1QJQS@1224|Proteobacteria,1THS1@1236|Gammaproteobacteria,1XXCN@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_6592_10 1116375.VEJY3_02200 0.0 1443.0 COG0642@1|root,COG0745@1|root,COG2198@1|root,COG0745@2|Bacteria,COG2198@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1XSC0@135623|Vibrionales 135623|Vibrionales T aerobic respiration control sensor protein arcB - 2.7.13.3 ko:K07648 ko02020,ko02026,map02020,map02026 M00456 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,Hpt,PAS,PAS_4,Response_reg k141_6592_11 1116375.VEJY3_02195 1.03e-216 599.0 COG1242@1|root,COG1242@2|Bacteria,1MUYF@1224|Proteobacteria,1RP94@1236|Gammaproteobacteria,1XSN0@135623|Vibrionales 135623|Vibrionales S Radical_SAM C-terminal domain yhcC - - ko:K07139 - - - - ko00000 - - - Radical_SAM,Radical_SAM_C k141_6592_12 1280001.BAOA01000021_gene936 0.0 2936.0 COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,1RN2W@1236|Gammaproteobacteria,1XTQD@135623|Vibrionales 135623|Vibrionales E Glutamate synthase gltB - 1.4.1.13,1.4.1.14 ko:K00265 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - GATase_2,GXGXG,Glu_syn_central,Glu_synthase k141_6592_13 1116375.VEJY3_02185 0.0 995.0 COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,1RMY7@1236|Gammaproteobacteria,1XSFD@135623|Vibrionales 135623|Vibrionales C COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases gltD - 1.4.1.13,1.4.1.14 ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - Fer4_20,Pyr_redox_2 k141_6592_14 1116375.VEJY3_02180 1.46e-125 393.0 COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,1RN2W@1236|Gammaproteobacteria,1XSWZ@135623|Vibrionales 135623|Vibrionales E Glutamate synthase gltB - 1.4.1.13,1.4.1.14 ko:K00265 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - GATase_2,GXGXG,Glu_syn_central,Glu_synthase k141_25714_1 1530186.JQEY01000001_gene1283 1.64e-42 154.0 COG0044@1|root,COG0044@2|Bacteria,1MW10@1224|Proteobacteria,2TSQH@28211|Alphaproteobacteria 28211|Alphaproteobacteria F COG0044 Dihydroorotase and related cyclic amidohydrolases dht - 3.5.2.2 ko:K01464 ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100 M00046 R02269,R03055,R08227 RC00632,RC00680 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Amidohydro_1 k141_25714_2 929703.KE386491_gene3863 1.67e-10 63.5 2EGCH@1|root,33A4A@2|Bacteria,4NVXN@976|Bacteroidetes,47S8X@768503|Cytophagia 976|Bacteroidetes S Putative lumazine-binding - - - - - - - - - - - - Lumazine_bd_2 k141_25714_3 536019.Mesop_4272 5.81e-51 174.0 COG1171@1|root,COG1171@2|Bacteria,1N574@1224|Proteobacteria,2URSK@28211|Alphaproteobacteria,43IF1@69277|Phyllobacteriaceae 28211|Alphaproteobacteria E Pyridoxal-phosphate dependent enzyme - - 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - - PALP k141_10273_1 926551.KB900715_gene2201 1.38e-05 45.8 2DFVK@1|root,2ZTBH@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k141_10273_2 1042377.AFPJ01000036_gene1191 2.51e-174 502.0 COG1752@1|root,COG1752@2|Bacteria,1MUI6@1224|Proteobacteria,1RN0G@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Patatin-like phospholipase - - - ko:K07001 - - - - ko00000 - - - Patatin k141_10273_3 1453501.JELR01000001_gene2708 1.67e-189 530.0 COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,1RMC5@1236|Gammaproteobacteria,465BH@72275|Alteromonadaceae 1236|Gammaproteobacteria V COG1131 ABC-type multidrug transport system, ATPase component yadG GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0016020,GO:0044464,GO:0050896,GO:0071944 - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_10273_4 1042377.AFPJ01000036_gene1193 5.23e-159 448.0 COG0842@1|root,COG0842@2|Bacteria,1MUH1@1224|Proteobacteria,1RP0Z@1236|Gammaproteobacteria,46426@72275|Alteromonadaceae 1236|Gammaproteobacteria V Transport permease protein yadH GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane k141_10273_5 1453501.JELR01000001_gene2706 1.24e-150 429.0 COG0780@1|root,COG2904@1|root,COG0780@2|Bacteria,COG2904@2|Bacteria,1MW0M@1224|Proteobacteria,1RNXM@1236|Gammaproteobacteria,4650F@72275|Alteromonadaceae 1236|Gammaproteobacteria S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) queF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016651,GO:0016657,GO:0018130,GO:0019438,GO:0033739,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.7.1.13 ko:K06879,ko:K09457 ko00790,ko01100,map00790,map01100 - R07605 RC01875 ko00000,ko00001,ko01000,ko03016 - - iSFV_1184.SFV_2663,iSF_1195.SF2807,iS_1188.S3002 QueF,QueF_N k141_5492_1 1294265.JCM21738_5070 2.59e-124 376.0 COG0507@1|root,COG0507@2|Bacteria,1TPZH@1239|Firmicutes,4HATQ@91061|Bacilli,1ZAYS@1386|Bacillus 91061|Bacilli L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity recD2 - 3.1.11.5 ko:K03581 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_30,HHH_4,HHH_5,UvrD_C_2 k141_20751_1 1042377.AFPJ01000027_gene2670 4.88e-201 584.0 COG3325@1|root,COG3979@1|root,COG3325@2|Bacteria,COG3979@2|Bacteria,1MWAR@1224|Proteobacteria,1RPNS@1236|Gammaproteobacteria,4672D@72275|Alteromonadaceae 1236|Gammaproteobacteria G Glyco_18 chiA - 3.2.1.14 ko:K01183 ko00520,ko01100,map00520,map01100 - R01206,R02334 RC00467 ko00000,ko00001,ko01000 - GH18 - CBM_5_12,ChitinaseA_N,Glyco_hydro_18,REJ k141_30186_1 1116375.VEJY3_20446 0.0 1226.0 2BXCB@1|root,2Z8QU@2|Bacteria,1MZ0I@1224|Proteobacteria,1RRGR@1236|Gammaproteobacteria 1236|Gammaproteobacteria M 3HB-oligomer hydrolase (3HBOH) - - 3.1.1.22 ko:K07518 ko00650,map00650 - R00048 RC00037,RC00094 ko00000,ko00001,ko01000 - - - 3HBOH k141_23315_1 1121091.AUMP01000031_gene1414 4.05e-34 128.0 COG0639@1|root,COG0639@2|Bacteria,1UYWX@1239|Firmicutes,4HEJF@91061|Bacilli 91061|Bacilli T Calcineurin-like phosphoesterase - - 3.1.3.16 ko:K01090 - - - - ko00000,ko01000 - - - Metallophos k141_22010_1 218284.CCDN010000004_gene3042 6.27e-38 141.0 COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,4HAB3@91061|Bacilli,1ZAPP@1386|Bacillus 91061|Bacilli JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity cshA GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 3.6.4.13 ko:K05592 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,Helicase_C k141_22010_2 218284.CCDN010000008_gene4100 9.84e-34 127.0 COG0551@1|root,COG0551@2|Bacteria,1UIX7@1239|Firmicutes,4ISVF@91061|Bacilli,1ZS76@1386|Bacillus 91061|Bacilli L Nuclease-related domain - - - - - - - - - - - - NERD k141_12693_2 1042377.AFPJ01000014_gene1665 5.38e-165 464.0 COG2908@1|root,COG2908@2|Bacteria,1MVKD@1224|Proteobacteria,1RQIA@1236|Gammaproteobacteria,464YT@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria HA62_17960 - - - - - - - - - - - Metallophos,Metallophos_2 k141_27029_2 1196028.ALEF01000062_gene1109 6.27e-109 319.0 COG0692@1|root,COG0692@2|Bacteria,1TPSN@1239|Firmicutes,4HBTR@91061|Bacilli,4C5H3@84406|Virgibacillus 91061|Bacilli L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine ung GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360 3.2.2.27 ko:K03648 ko03410,ko05340,map03410,map05340 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG k141_23350_1 1294265.JCM21738_5175 1.44e-99 291.0 COG0655@1|root,COG0655@2|Bacteria,1TSY9@1239|Firmicutes,4H9MQ@91061|Bacilli,1ZBKC@1386|Bacillus 91061|Bacilli S Belongs to the WrbA family wrbA - 1.6.5.2 ko:K03809 ko00130,ko01110,map00130,map01110 - R02964,R03643,R03816 RC00819 ko00000,ko00001,ko01000 - - - FMN_red k141_32602_1 945713.IALB_0987 5.18e-21 93.2 COG3040@1|root,COG3040@2|Bacteria 2|Bacteria M lipid binding - - - ko:K03098 - - - - ko00000,ko04147 - - - Lipocalin_2 k141_35167_1 879309.HMPREF9199_1076 2.44e-55 194.0 COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H360@909932|Negativicutes 909932|Negativicutes M Penicillin-binding Protein pbpD - 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase k141_18591_3 1042377.AFPJ01000032_gene2830 5.5e-104 326.0 COG2959@1|root,COG2959@2|Bacteria,1MY3A@1224|Proteobacteria,1RNJY@1236|Gammaproteobacteria,467C6@72275|Alteromonadaceae 1236|Gammaproteobacteria H enzyme of heme biosynthesis hemX - 2.1.1.107,4.2.1.75 ko:K02496,ko:K13543 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R03165,R03194 RC00003,RC00871,RC01861 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b3803,iBWG_1329.BWG_3482,iECDH1ME8569_1439.ECDH1ME8569_3682,iECUMN_1333.ECUMN_4327,iECs_1301.ECs4733,iEcDH1_1363.EcDH1_4176,iJO1366.b3803,iJR904.b3803,iPC815.YPO3851,iUMN146_1321.UM146_19140,iY75_1357.Y75_RS18060,iZ_1308.Z5317 HemX k141_18591_4 1042377.AFPJ01000032_gene2829 1.25e-97 293.0 COG1587@1|root,COG1587@2|Bacteria,1MWZD@1224|Proteobacteria,1RM9K@1236|Gammaproteobacteria,467BQ@72275|Alteromonadaceae 1236|Gammaproteobacteria H COG1587 Uroporphyrinogen-III synthase hemD GO:0003674,GO:0003824,GO:0004852,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.75 ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R03165 RC01861 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_0187,iSBO_1134.SBO_3815 HEM4 k141_18591_5 1042377.AFPJ01000032_gene2828 3.37e-163 463.0 COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,1RMQ8@1236|Gammaproteobacteria,464JS@72275|Alteromonadaceae 1236|Gammaproteobacteria H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps hemC GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018065,GO:0018130,GO:0018160,GO:0018193,GO:0018198,GO:0019438,GO:0019538,GO:0033013,GO:0033014,GO:0034641,GO:0036211,GO:0042168,GO:0042440,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00084 RC02317 ko00000,ko00001,ko00002,ko01000 - - iEC55989_1330.EC55989_4275,iECH74115_1262.ECH74115_5243,iECIAI1_1343.ECIAI1_3991,iECO103_1326.ECO103_4362,iECO111_1330.ECO111_4628,iECO26_1355.ECO26_4784,iECSE_1348.ECSE_4086,iEKO11_1354.EKO11_4554,iPC815.YPO3849 Porphobil_deam,Porphobil_deamC k141_18591_6 1279017.AQYJ01000027_gene1599 3.7e-58 182.0 COG0816@1|root,COG0816@2|Bacteria,1RDHZ@1224|Proteobacteria,1S96Q@1236|Gammaproteobacteria,466VN@72275|Alteromonadaceae 1236|Gammaproteobacteria L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA yqgF GO:0000966,GO:0000967,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - ko:K07447 - - - - ko00000,ko01000 - - - RuvX k141_12899_1 314287.GB2207_03404 4.27e-63 210.0 COG0654@1|root,COG0654@2|Bacteria,1NSGN@1224|Proteobacteria,1T22A@1236|Gammaproteobacteria,1J4PW@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria CH Tryptophan halogenase - - 1.14.19.9 ko:K14266 ko00404,ko01130,map00404,map01130 M00789,M00790 R09570 RC00949 ko00000,ko00001,ko00002,ko01000 - - - Trp_halogenase k141_993_1 761193.Runsl_0766 0.000459 48.1 COG4775@1|root,COG4775@2|Bacteria,4NICB@976|Bacteroidetes,47Y2B@768503|Cytophagia 976|Bacteroidetes M Surface antigen - - - - - - - - - - - - Bac_surface_Ag k141_20945_2 1279017.AQYJ01000029_gene3647 1.58e-180 505.0 COG3246@1|root,COG3246@2|Bacteria,1MZTP@1224|Proteobacteria,1RRUP@1236|Gammaproteobacteria,466BX@72275|Alteromonadaceae 1236|Gammaproteobacteria S Pfam:Kce - - - - - - - - - - - - BKACE k141_20945_3 1453501.JELR01000001_gene2142 1.68e-35 133.0 COG1115@1|root,COG1115@2|Bacteria,1MUI3@1224|Proteobacteria,1RMNF@1236|Gammaproteobacteria,464HE@72275|Alteromonadaceae 1236|Gammaproteobacteria E alanine symporter yaaJ GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03310 - - - - ko00000 2.A.25 - iEcE24377_1341.EcE24377A_0007 Na_Ala_symp k141_14262_1 866895.HBHAL_1321 3.29e-71 234.0 COG0209@1|root,COG0209@2|Bacteria,1TPFH@1239|Firmicutes,4H9X0@91061|Bacilli,3NEQT@45667|Halobacillus 91061|Bacilli F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdA - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN k141_24687_1 1385511.N783_03895 3.43e-98 299.0 COG4962@1|root,COG4962@2|Bacteria,1TQ0Z@1239|Firmicutes,4HAQM@91061|Bacilli 91061|Bacilli U Pilus assembly protein cpaF - - ko:K02283 - - - - ko00000,ko02035,ko02044 - - - T2SSE k141_3186_1 218284.CCDN010000004_gene3151 3.96e-88 272.0 COG0189@1|root,COG0189@2|Bacteria,1TSWS@1239|Firmicutes,4HCJA@91061|Bacilli,1ZAR6@1386|Bacillus 91061|Bacilli HJ YheC/D like ATP-grasp yheD GO:0005575,GO:0005623,GO:0042601,GO:0042763,GO:0044464 - - - - - - - - - - ATPgrasp_YheCD k141_3186_2 218284.CCDN010000004_gene3150 7.06e-49 167.0 COG0189@1|root,COG0189@2|Bacteria,1UZ79@1239|Firmicutes,4HTI1@91061|Bacilli,1ZBQZ@1386|Bacillus 91061|Bacilli HJ COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase) - - - - - - - - - - - - ATPgrasp_YheCD k141_6962_1 56107.Cylst_3919 1.26e-27 115.0 COG0058@1|root,COG0058@2|Bacteria,1G1HB@1117|Cyanobacteria,1HM60@1161|Nostocales 1117|Cyanobacteria G PFAM glycosyl transferase, family 35 glgP - 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 - R02111 - ko00000,ko00001,ko01000 - GT35 - DUF3417,Phosphorylase k141_17404_3 1348635.BBJY01000020_gene2752 3.65e-56 181.0 COG4970@1|root,COG4970@2|Bacteria,1NGHS@1224|Proteobacteria,1SGGC@1236|Gammaproteobacteria,1XXYJ@135623|Vibrionales 135623|Vibrionales NU COG4970 Tfp pilus assembly protein FimT VP0657 - - ko:K08084 - - - - ko00000,ko02044 3.A.15.2 - - GspH,N_methyl k141_17404_4 223926.28805642 1.34e-71 218.0 COG4968@1|root,COG4968@2|Bacteria,1N6QE@1224|Proteobacteria,1SCBS@1236|Gammaproteobacteria,1XYJQ@135623|Vibrionales 135623|Vibrionales NU COG4968 Tfp pilus assembly protein PilE - - - ko:K02655 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - ComP_DUS,N_methyl k141_17404_5 1116375.VEJY3_03005 3.06e-246 679.0 COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,1RNHY@1236|Gammaproteobacteria,1XT3G@135623|Vibrionales 135623|Vibrionales O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins dnaJ GO:0006457,GO:0008150,GO:0009987 - ko:K03686 - - - - ko00000,ko03029,ko03110 - - - DnaJ,DnaJ_C,DnaJ_CXXCXGXG k141_17404_6 223926.28805639 0.0 1159.0 COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,1RMDD@1236|Gammaproteobacteria,1XUDT@135623|Vibrionales 135623|Vibrionales O Heat shock 70 kDa protein dnaK GO:0006457,GO:0008150,GO:0009987 - ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 - - HSP70 k141_17404_7 945550.VISI1226_15031 5.31e-108 315.0 COG0576@1|root,COG0576@2|Bacteria,1RH8T@1224|Proteobacteria,1S5W5@1236|Gammaproteobacteria,1XT2V@135623|Vibrionales 135623|Vibrionales O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ grpE GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0008150,GO:0009987,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - ko:K03687 - - - - ko00000,ko03029,ko03110 - - - GrpE k141_17404_8 1219076.N646_2803 4.89e-205 568.0 COG0061@1|root,COG0061@2|Bacteria,1MUBC@1224|Proteobacteria,1RP84@1236|Gammaproteobacteria,1XTTS@135623|Vibrionales 135623|Vibrionales F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP nadK - 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 - R00104 RC00002,RC00078 ko00000,ko00001,ko01000 - - - NAD_kinase k141_17404_9 1116375.VEJY3_02980 0.0 1018.0 COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,1RNPZ@1236|Gammaproteobacteria,1XSEX@135623|Vibrionales 135623|Vibrionales L May be involved in recombinational repair of damaged DNA recN - - ko:K03631 - - - - ko00000,ko03400 - - - AAA_23,SMC_N k141_17404_10 223926.28805633 2.13e-79 236.0 COG2913@1|root,COG2913@2|Bacteria,1N6YW@1224|Proteobacteria,1SCTT@1236|Gammaproteobacteria,1XXFF@135623|Vibrionales 135623|Vibrionales M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamE - - ko:K06186 - - - - ko00000,ko02000 1.B.33.1 - - SmpA_OmlA k141_17404_11 1116375.VEJY3_02970 2.55e-47 153.0 COG2914@1|root,COG2914@2|Bacteria,1MZCH@1224|Proteobacteria,1SCHG@1236|Gammaproteobacteria,1XXAY@135623|Vibrionales 135623|Vibrionales S Belongs to the UPF0125 (RnfH) family yfjF - - ko:K09801 - - - - ko00000 - - - Ub-RnfH k141_23711_1 1236573.K4LRR7_9CAUD 2.44e-29 116.0 4QAPV@10239|Viruses,4QV7H@35237|dsDNA viruses no RNA stage,4QPC3@28883|Caudovirales,4QKMY@10699|Siphoviridae 10699|Siphoviridae S DNA binding - - - - - - - - - - - - - k141_23711_2 935837.JAEK01000054_gene1491 4.63e-09 54.7 COG3655@1|root,COG3655@2|Bacteria,1VKVP@1239|Firmicutes 1239|Firmicutes K Cro/C1-type HTH DNA-binding domain - - - ko:K07727 - - - - ko00000,ko03000 - - - HTH_26 k141_23711_3 1295642.H839_08129 1.23e-25 96.7 COG3655@1|root,COG3655@2|Bacteria 2|Bacteria K Transcriptional regulator - - - ko:K07727 - - - - ko00000,ko03000 - - - HTH_26,HTH_3 k141_5738_1 358681.BBR47_52890 1.34e-29 118.0 COG0531@1|root,COG0531@2|Bacteria,1UZ73@1239|Firmicutes,4HE8G@91061|Bacilli,26QE3@186822|Paenibacillaceae 91061|Bacilli E Spore gernimation protein M1-959 - - ko:K06296 - - - - ko00000,ko02000 2.A.3.9.3 - - Spore_permease k141_22366_1 861299.J421_3598 7.72e-51 173.0 COG1071@1|root,COG1071@2|Bacteria,1ZT5G@142182|Gemmatimonadetes 2|Bacteria C The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) bfmBA - 1.2.4.1,1.2.4.4 ko:K00161,ko:K11381,ko:K21416 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00036,M00307 R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh,Transket_pyr,Transketolase_C k141_34191_1 218284.CCDN010000008_gene4246 2.38e-153 444.0 COG0365@1|root,COG0365@2|Bacteria,1TQTI@1239|Firmicutes,4H9PN@91061|Bacilli,1ZBDX@1386|Bacillus 91061|Bacilli I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases acsA - 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 - - - AMP-binding,AMP-binding_C k141_15071_1 1397528.Q671_08325 1.31e-90 273.0 COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,1RNCK@1236|Gammaproteobacteria,1XJ0K@135619|Oceanospirillales 135619|Oceanospirillales Q C4-dicarboxylate ABC transporter substrate-binding protein - - - - - - - - - - - - DctP k141_15071_2 1397528.Q671_08320 1.07e-07 52.4 COG4664@1|root,COG4665@1|root,COG4664@2|Bacteria,COG4665@2|Bacteria,1R4MZ@1224|Proteobacteria,1RMR6@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q COG4664 TRAP-type mannitol chloroaromatic compound transport system large permease component - - - - - - - - - - - - DctM,DctQ k141_29356_1 1042377.AFPJ01000024_gene706 1e-112 338.0 COG0651@1|root,COG0651@2|Bacteria,1MURB@1224|Proteobacteria,1RQBG@1236|Gammaproteobacteria,465QH@72275|Alteromonadaceae 1236|Gammaproteobacteria CP COG0651 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit - - - ko:K05568 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - Proton_antipo_M k141_37577_1 1279017.AQYJ01000025_gene762 8.54e-98 301.0 COG4783@1|root,COG4783@2|Bacteria,1QTUQ@1224|Proteobacteria,1T1HY@1236|Gammaproteobacteria,46DF2@72275|Alteromonadaceae 1236|Gammaproteobacteria S Oxygen tolerance batD - - - - - - - - - - - BatD k141_35453_1 223926.28806614 9.6e-126 360.0 COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,1RMX1@1236|Gammaproteobacteria,1XTEU@135623|Vibrionales 135623|Vibrionales E COG1126 ABC-type polar amino acid transport system, ATPase component aapP - 3.6.3.21 ko:K02028,ko:K09972 ko02010,map02010 M00232,M00236 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3,3.A.1.3.17,3.A.1.3.18,3.A.1.3.7,3.A.1.3.8 - - ABC_tran k141_35453_2 1116375.VEJY3_07700 1.45e-157 448.0 COG0765@1|root,COG0765@2|Bacteria,1MV3I@1224|Proteobacteria,1RPJR@1236|Gammaproteobacteria,1XTN4@135623|Vibrionales 135623|Vibrionales P COG0765 ABC-type amino acid transport system, permease component aapM - - ko:K09971 ko02010,map02010 M00232 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.18,3.A.1.3.7,3.A.1.3.8 - - BPD_transp_1 k141_24688_1 1294265.JCM21738_5088 1.39e-110 318.0 COG0219@1|root,COG0219@2|Bacteria,1V3GW@1239|Firmicutes,4HFNY@91061|Bacilli,1ZFKH@1386|Bacillus 91061|Bacilli J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily cspR - 2.1.1.207 ko:K03216 - - - - ko00000,ko01000,ko03016 - - - SpoU_methylase k141_18991_1 1116375.VEJY3_12185 0.0 988.0 COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,1RS89@1236|Gammaproteobacteria,1XT65@135623|Vibrionales 135623|Vibrionales L COG0514 Superfamily II DNA helicase - - 3.6.4.12 ko:K03654 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecQ_Zn_bind k141_18991_2 1116375.VEJY3_12190 4.91e-242 666.0 COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,1RMFM@1236|Gammaproteobacteria,1XTDB@135623|Vibrionales 135623|Vibrionales L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII dinB - 2.7.7.7 ko:K02346 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH k141_18991_3 1116375.VEJY3_12195 2.15e-46 149.0 2DNUJ@1|root,32Z85@2|Bacteria,1QTZU@1224|Proteobacteria,1T1JC@1236|Gammaproteobacteria,1XZ5B@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF2789) - - - - - - - - - - - - DUF2789 k141_18991_4 1280001.BAOA01000081_gene2954 9.89e-43 140.0 COG2991@1|root,COG2991@2|Bacteria,1N8TF@1224|Proteobacteria,1SCB5@1236|Gammaproteobacteria,1XYBR@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria - - - ko:K05952 - - - - ko00000 - - - NqrM k141_18991_5 223926.28807343 2.94e-61 196.0 COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,1RNMZ@1236|Gammaproteobacteria,1XSQ4@135623|Vibrionales 135623|Vibrionales H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein apbE - 2.7.1.180 ko:K03734 - - - - ko00000,ko01000 - - - ApbE k141_36357_1 218284.CCDN010000005_gene3265 3.12e-38 134.0 COG0664@1|root,COG0664@2|Bacteria,1V1AS@1239|Firmicutes,4HF4V@91061|Bacilli,1ZD74@1386|Bacillus 91061|Bacilli K COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases fnr - - - - - - - - - - - HTH_Crp_2,cNMP_binding k141_36357_2 218284.CCDN010000005_gene3266 1.19e-112 328.0 COG1968@1|root,COG1968@2|Bacteria,1TPFA@1239|Firmicutes,4HCE7@91061|Bacilli,1ZC3Z@1386|Bacillus 91061|Bacilli V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin uppP - 3.6.1.27 ko:K06153 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - BacA k141_4381_1 706191.PANA_1037 3.01e-10 61.6 COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,1RPX3@1236|Gammaproteobacteria,3VXP9@53335|Pantoea 1236|Gammaproteobacteria F Belongs to the 5'-nucleotidase family ushA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0006139,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008768,GO:0009225,GO:0009987,GO:0016311,GO:0016462,GO:0016787,GO:0016788,GO:0016791,GO:0016817,GO:0016818,GO:0030288,GO:0030313,GO:0031975,GO:0034641,GO:0042578,GO:0042597,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:1901135,GO:1901360 3.1.3.5,3.6.1.45 ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - iEC55989_1330.EC55989_0493,iECIAI1_1343.ECIAI1_0483,iECO103_1326.ECO103_0456,iECSE_1348.ECSE_0505 5_nucleotid_C,Metallophos k141_4381_2 1056820.KB900630_gene1466 3.08e-171 492.0 COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,1RP7E@1236|Gammaproteobacteria,2PPUQ@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria J Amidase gatA - 3.5.1.84,6.3.5.6,6.3.5.7 ko:K02433,ko:K19837 ko00791,ko00970,ko01100,ko01120,map00791,map00970,map01100,map01120 - R03905,R04212,R05563 RC00010,RC01287 ko00000,ko00001,ko01000,ko03029 - - - Amidase k141_9372_2 218284.CCDN010000005_gene3249 3.72e-73 230.0 COG1175@1|root,COG1175@2|Bacteria,1TR2A@1239|Firmicutes,4HB8H@91061|Bacilli,1ZBHD@1386|Bacillus 91061|Bacilli P COG1175 ABC-type sugar transport systems, permease components malC GO:0003674,GO:0003824,GO:0005215,GO:0005363,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015154,GO:0015157,GO:0015399,GO:0015405,GO:0015422,GO:0015423,GO:0015766,GO:0015768,GO:0015772,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0032991,GO:0034219,GO:0042623,GO:0042626,GO:0043190,GO:0043211,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990060,GO:1990351 - ko:K15771 ko02010,map02010 M00491 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.16,3.A.1.1.2 - iYO844.BSU34150 BPD_transp_1 k141_15072_1 1453501.JELR01000001_gene2050 3.06e-112 347.0 COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,1RN03@1236|Gammaproteobacteria,4643E@72275|Alteromonadaceae 1236|Gammaproteobacteria L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrA GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0018130,GO:0019438,GO:0032774,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042493,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097659,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 5.99.1.3 ko:K02469 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseA_C,DNA_topoisoIV k141_23712_2 1385514.N782_14925 1.87e-15 77.0 COG0025@1|root,COG0025@2|Bacteria,1TR4G@1239|Firmicutes,4HBJR@91061|Bacilli,2YA51@289201|Pontibacillus 91061|Bacilli P Sodium proton antiporter - - - ko:K03316 - - - - ko00000 2.A.36 - - Na_H_Exchanger k141_12914_2 218284.CCDN010000001_gene41 3.44e-181 521.0 COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,4H9KD@91061|Bacilli,1ZBBU@1386|Bacillus 91061|Bacilli KLT serine threonine protein kinase prkC GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 ko:K08884,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PASTA,Pkinase k141_16304_1 42565.FP66_01965 2.69e-130 376.0 COG1868@1|root,COG1868@2|Bacteria,1MX01@1224|Proteobacteria,1RQ8M@1236|Gammaproteobacteria,1XHYT@135619|Oceanospirillales 135619|Oceanospirillales N FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation fliM - - ko:K02416 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02035 - - - FliM,FliMN_C k141_3187_1 866895.HBHAL_5041 1.37e-13 69.3 COG0667@1|root,COG0667@2|Bacteria,1TPIY@1239|Firmicutes,4HA4Q@91061|Bacilli,3NEPW@45667|Halobacillus 91061|Bacilli C Aldo/keto reductase family - - - - - - - - - - - - Aldo_ket_red k141_3187_2 1397699.JNIS01000001_gene1520 1.13e-58 191.0 COG0667@1|root,COG0667@2|Bacteria,1UKPC@1239|Firmicutes,4HCHM@91061|Bacilli 91061|Bacilli C Aldo/keto reductase family - - - - - - - - - - - - Aldo_ket_red k141_14263_1 1274524.BSONL12_22598 0.000198 42.7 COG0311@1|root,COG0311@2|Bacteria,1V3I6@1239|Firmicutes,4HFSZ@91061|Bacilli,1ZD5C@1386|Bacillus 91061|Bacilli H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS pdxT GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 ko:K08681 ko00750,map00750 - R07456 RC00010,RC01783,RC03043 ko00000,ko00001,ko01000 - - - SNO k141_14263_2 218284.CCDN010000012_gene4436 1.49e-178 501.0 COG0214@1|root,COG0214@2|Bacteria,1TPSZ@1239|Firmicutes,4H9RA@91061|Bacilli,1ZB36@1386|Bacillus 91061|Bacilli H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively pdxS GO:0003674,GO:0005488,GO:0005515,GO:0042802 4.3.3.6 ko:K06215 ko00750,map00750 - R07456 RC00010,RC01783,RC03043 ko00000,ko00001,ko01000 - - - SOR_SNZ k141_19965_1 1294265.JCM21738_4193 6.38e-10 62.8 29SR4@1|root,30DX0@2|Bacteria,1V1H9@1239|Firmicutes,4HFRK@91061|Bacilli,1ZD7U@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF4179) - - - - - - - - - - - - DUF4179 k141_15073_1 1279017.AQYJ01000023_gene3252 3.8e-45 152.0 COG1881@1|root,COG1881@2|Bacteria,1N0Y4@1224|Proteobacteria,1S400@1236|Gammaproteobacteria,466X5@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG1881 Phospholipid-binding protein ybhB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K06910 - - - - ko00000 - - - PBP k141_15073_2 1123388.AQWU01000043_gene405 1.79e-10 62.4 COG1171@1|root,COG1171@2|Bacteria,1WI3F@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus E PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit - - 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - - PALP k141_14264_1 1117379.BABA_15032 4.44e-13 70.1 COG0697@1|root,COG0697@2|Bacteria,1TP7K@1239|Firmicutes,4HAH1@91061|Bacilli,1ZBEF@1386|Bacillus 91061|Bacilli EG Spore germination protein gerAA_1 - - ko:K06295 - - - - ko00000 - - - GerA k141_14264_2 218284.CCDN010000001_gene1309 7.57e-35 129.0 COG0531@1|root,COG0531@2|Bacteria,1V1FX@1239|Firmicutes,4HFZN@91061|Bacilli,1ZFS6@1386|Bacillus 91061|Bacilli E Spore germination protein gerKB - - - - - - - - - - - Spore_permease k141_5739_1 218284.CCDN010000007_gene3960 1.83e-168 501.0 COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,1TQAD@1239|Firmicutes,4HCMS@91061|Bacilli,1ZBF6@1386|Bacillus 91061|Bacilli EI Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly icmF GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046906,GO:0046983,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 ko:K11942 - - - - ko00000,ko01000 - - - ArgK,B12-binding,MM_CoA_mutase k141_4382_1 935837.JAEK01000005_gene4530 9.46e-05 44.7 COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,4HAK8@91061|Bacilli,1ZD3R@1386|Bacillus 91061|Bacilli H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine coaBC - 4.1.1.36,6.3.2.5 ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 - - - DFP,Flavoprotein k141_4382_2 1294265.JCM21738_234 1.49e-68 217.0 COG1198@1|root,COG1198@2|Bacteria,1TNYB@1239|Firmicutes,4H9WW@91061|Bacilli,1ZCBY@1386|Bacillus 91061|Bacilli L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA priA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - ko:K04066 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,ResIII k141_25998_2 1116375.VEJY3_04780 5.48e-124 355.0 COG3070@1|root,COG3070@2|Bacteria,1RDWD@1224|Proteobacteria,1S496@1236|Gammaproteobacteria,1XUVA@135623|Vibrionales 135623|Vibrionales K COG3070 Regulator of competence-specific genes tfoX GO:0006810,GO:0007154,GO:0008150,GO:0009290,GO:0009292,GO:0009294,GO:0009605,GO:0009987,GO:0009991,GO:0015931,GO:0030420,GO:0031668,GO:0044764,GO:0050657,GO:0050896,GO:0051027,GO:0051179,GO:0051234,GO:0051704,GO:0051716,GO:0071496,GO:0071702,GO:0071705,GO:0098657 - ko:K07343 - - - - ko00000 - - - TfoX_C,TfoX_N k141_25998_3 223926.28806017 1.97e-231 638.0 COG1609@1|root,COG1609@2|Bacteria,1MVUR@1224|Proteobacteria,1RN2K@1236|Gammaproteobacteria,1XU47@135623|Vibrionales 135623|Vibrionales K Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression purR GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 - ko:K03604 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 k141_25998_4 1116375.VEJY3_04790 6.04e-137 389.0 COG3381@1|root,COG3381@2|Bacteria,1RJ3Z@1224|Proteobacteria,1S8M5@1236|Gammaproteobacteria,1XTZ3@135623|Vibrionales 135623|Vibrionales O Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor torD - - ko:K03533 ko02020,map02020 - - - ko00000,ko00001,ko02000 5.A.3.4 - - Nitrate_red_del k141_25998_5 223926.28806019 2.99e-157 442.0 COG0745@1|root,COG0745@2|Bacteria,1MWJG@1224|Proteobacteria,1RPU3@1236|Gammaproteobacteria,1XSI9@135623|Vibrionales 135623|Vibrionales K COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain torR - - ko:K07772 ko02020,map02020 M00455 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C k141_25998_6 1219076.N646_0097 1.2e-168 473.0 COG1434@1|root,COG1434@2|Bacteria,1MVW8@1224|Proteobacteria,1RNZC@1236|Gammaproteobacteria,1XUG3@135623|Vibrionales 135623|Vibrionales S DUF218 domain - - - - - - - - - - - - DUF218 k141_25998_7 1219076.N646_0098 5.42e-193 536.0 COG2227@1|root,COG2227@2|Bacteria,1MY0S@1224|Proteobacteria,1RP69@1236|Gammaproteobacteria,1XSUE@135623|Vibrionales 135623|Vibrionales J Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs cmoM - - ko:K06219 - - - - ko00000 - - - Methyltransf_11,Methyltransf_31 k141_25998_8 1116375.VEJY3_04810 3.72e-299 818.0 COG3006@1|root,COG3006@2|Bacteria,1N0D6@1224|Proteobacteria,1RN7P@1236|Gammaproteobacteria,1XSU3@135623|Vibrionales 135623|Vibrionales D Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity mukF - - ko:K03633 - - - - ko00000,ko03036 - - - KicB,MukF_C,MukF_M k141_25998_9 223926.28806023 3.49e-149 422.0 COG3095@1|root,COG3095@2|Bacteria,1MXYN@1224|Proteobacteria,1RRBE@1236|Gammaproteobacteria,1XTJ6@135623|Vibrionales 135623|Vibrionales D Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF mukE GO:0007059,GO:0008150,GO:0009987 - ko:K03804 - - - - ko00000,ko03036 - - - MukE k141_25998_10 1280001.BAOA01000060_gene2324 6.02e-224 660.0 COG3096@1|root,COG3096@2|Bacteria,1MUWM@1224|Proteobacteria,1RPFF@1236|Gammaproteobacteria,1XUHB@135623|Vibrionales 135623|Vibrionales D Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division mukB GO:0007059,GO:0008150,GO:0009987 - ko:K03632 - - - - ko00000,ko03036 - - - MukB,MukB_hinge,SbcCD_C k141_12915_1 218284.CCDN010000001_gene1733 8.25e-69 218.0 COG4191@1|root,COG4191@2|Bacteria,1UZ9W@1239|Firmicutes,4HDK2@91061|Bacilli,1ZD85@1386|Bacillus 91061|Bacilli T Histidine kinase - - 2.7.13.3 ko:K07697 ko02020,map02020 M00485 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - 5TM-5TMR_LYT,HATPase_c,HisKA k141_34193_2 543526.Htur_1585 1.6e-26 108.0 COG2116@1|root,arCOG03454@2157|Archaea,2XTKF@28890|Euryarchaeota,23TA8@183963|Halobacteria 183963|Halobacteria P COG2116 Formate nitrite family of transporters - - - ko:K21990 - - - - ko00000 1.A.16.4 - - Form_Nir_trans k141_16305_1 1123401.JHYQ01000012_gene2907 8.94e-27 105.0 COG1028@1|root,COG1028@2|Bacteria,1RHYX@1224|Proteobacteria,1S0GN@1236|Gammaproteobacteria,4612H@72273|Thiotrichales 72273|Thiotrichales IQ Enoyl-(Acyl carrier protein) reductase - - - - - - - - - - - - adh_short k141_16305_2 861299.J421_3955 5.01e-10 61.2 COG2204@1|root,COG2204@2|Bacteria,1ZSWY@142182|Gemmatimonadetes 142182|Gemmatimonadetes T Bacterial regulatory protein, Fis family - - - - - - - - - - - - HTH_8,Sigma54_activat k141_18994_1 218284.CCDN010000001_gene104 2.79e-82 256.0 COG1323@1|root,COG1323@2|Bacteria,1TPP2@1239|Firmicutes,4HAZJ@91061|Bacilli,1ZC63@1386|Bacillus 91061|Bacilli S Belongs to the UPF0348 family ylbM - - - - - - - - - - - HIGH_NTase1 k141_36358_1 1279017.AQYJ01000020_gene1331 8.03e-40 139.0 COG0454@1|root,COG0456@2|Bacteria,1NGUX@1224|Proteobacteria,1SV6D@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Acetyltransferase (GNAT) family - - - - - - - - - - - - - k141_23714_1 796606.BMMGA3_01745 9.67e-100 304.0 COG2225@1|root,COG2225@2|Bacteria,1TPE8@1239|Firmicutes,4H9ST@91061|Bacilli,1ZBY7@1386|Bacillus 91061|Bacilli C Belongs to the malate synthase family aceB - 2.3.3.9 ko:K01638 ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200 M00012 R00472 RC00004,RC00308,RC02747 ko00000,ko00001,ko00002,ko01000 - - - Malate_synthase k141_11767_1 309801.trd_0463 2.74e-50 177.0 COG1233@1|root,COG1233@2|Bacteria,2G5SE@200795|Chloroflexi,27Y46@189775|Thermomicrobia 189775|Thermomicrobia Q Flavin containing amine oxidoreductase - - - - - - - - - - - - Amino_oxidase k141_34208_1 1280001.BAOA01000061_gene4472 1.85e-263 720.0 COG1085@1|root,COG1085@2|Bacteria,1MU3E@1224|Proteobacteria,1RMDK@1236|Gammaproteobacteria,1XTKC@135623|Vibrionales 135623|Vibrionales H Galactose-1-phosphate uridylyltransferase galT - 2.7.7.12 ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 M00362,M00554,M00632 R00955 RC00002 ko00000,ko00001,ko00002,ko01000 - - - GalP_UDP_tr_C,GalP_UDP_transf k141_3210_2 1116375.VEJY3_08370 1.02e-111 323.0 COG1670@1|root,COG1670@2|Bacteria,1RCX2@1224|Proteobacteria,1S91P@1236|Gammaproteobacteria,1Y26W@135623|Vibrionales 135623|Vibrionales J Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_3 k141_9399_1 1349767.GJA_3786 1.11e-06 54.7 2E3CB@1|root,32YBM@2|Bacteria,1N6WD@1224|Proteobacteria,2VVST@28216|Betaproteobacteria 28216|Betaproteobacteria S Domain of unknown function (DUF4154) - - - - - - - - - - - - DUF4154 k141_9399_2 1453501.JELR01000002_gene422 2.45e-41 147.0 COG0189@1|root,COG4067@1|root,COG0189@2|Bacteria,COG4067@2|Bacteria,1MX62@1224|Proteobacteria,1RM8B@1236|Gammaproteobacteria,469U8@72275|Alteromonadaceae 1236|Gammaproteobacteria HJO Putative ATP-dependant zinc protease rimK - - ko:K05844 - - - - ko00000,ko01000,ko03009 - - - RimK,Zn_protease k141_29387_1 218284.CCDN010000001_gene152 4.09e-136 396.0 COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,4HB3K@91061|Bacilli,1ZCJR@1386|Bacillus 91061|Bacilli C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes pdhD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyr_redox_2,Pyr_redox_dim k141_20967_1 441769.ABFU01000007_gene2810 5.4e-62 214.0 COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,4HAFP@91061|Bacilli,1ZBJ3@1386|Bacillus 91061|Bacilli V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran k141_12931_1 198467.NP92_14585 3.06e-138 410.0 COG1674@1|root,COG1674@2|Bacteria,1TWB0@1239|Firmicutes,4HCGJ@91061|Bacilli,21X2C@150247|Anoxybacillus 91061|Bacilli D FtsK/SpoIIIE family - - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_SpoIIIE k141_36383_1 218284.CCDN010000005_gene3372 2.24e-84 254.0 COG0388@1|root,COG0388@2|Bacteria,1TQDK@1239|Firmicutes,4HC44@91061|Bacilli,1ZB5Z@1386|Bacillus 91061|Bacilli S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase mtnU - 3.5.1.3 ko:K13566 ko00250,map00250 - R00269,R00348 RC00010 ko00000,ko00001,ko01000 - - - CN_hydrolase k141_1039_1 1042377.AFPJ01000015_gene1610 6.06e-97 292.0 COG0604@1|root,COG0604@2|Bacteria,1QY04@1224|Proteobacteria,1RSP0@1236|Gammaproteobacteria,46BBM@72275|Alteromonadaceae 1236|Gammaproteobacteria C Zinc-binding dehydrogenase - - 1.1.1.1 ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N,ADH_zinc_N_2,KR,PP-binding,PS-DH k141_1039_2 1042377.AFPJ01000034_gene2415 4.98e-107 313.0 COG1225@1|root,COG1225@2|Bacteria,1MWFZ@1224|Proteobacteria,1RZ28@1236|Gammaproteobacteria,46CDJ@72275|Alteromonadaceae 1236|Gammaproteobacteria O Redoxin - - - - - - - - - - - - AhpC-TSA k141_5757_1 218284.CCDN010000001_gene24 1.11e-154 469.0 COG1196@1|root,COG1196@2|Bacteria,1TPJV@1239|Firmicutes,4HB89@91061|Bacilli,1ZAWM@1386|Bacillus 91061|Bacilli D Required for chromosome condensation and partitioning smc GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K03529 - - - - ko00000,ko03036 - - - SMC_N,SMC_hinge k141_23746_1 1279017.AQYJ01000027_gene1934 1.63e-79 252.0 COG1785@1|root,COG1785@2|Bacteria,1MXI2@1224|Proteobacteria,1RNG8@1236|Gammaproteobacteria,46460@72275|Alteromonadaceae 1236|Gammaproteobacteria P Belongs to the alkaline phosphatase family phoA - 3.1.3.1 ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 M00126 R02135,R04620 RC00017 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 - - - Alk_phosphatase k141_26032_2 218284.CCDN010000004_gene3023 1.46e-55 176.0 COG3091@1|root,COG3091@2|Bacteria,1V6NU@1239|Firmicutes,4HIHY@91061|Bacilli,1ZG8Y@1386|Bacillus 91061|Bacilli S Belongs to the SprT family ydcK - - ko:K03095 - - - - ko00000 - - - SprT-like,Zn_ribbon_SprT k141_1926_1 1280001.BAOA01000129_gene1250 5.23e-72 226.0 COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,1RN0B@1236|Gammaproteobacteria,1XUSR@135623|Vibrionales 135623|Vibrionales NU COG5008 Tfp pilus assembly protein, ATPase PilU pilU - - ko:K02670 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE k141_1926_2 1116375.VEJY3_13450 9.44e-236 650.0 COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,1RN8G@1236|Gammaproteobacteria,1XUQV@135623|Vibrionales 135623|Vibrionales NU COG2805 Tfp pilus assembly protein, pilus retraction ATPase PilT pilT - - ko:K02669 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE k141_1926_3 1116375.VEJY3_13455 5.97e-150 424.0 COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,1RNPM@1236|Gammaproteobacteria,1XT7U@135623|Vibrionales 135623|Vibrionales S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis yggS GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 - ko:K06997 - - - - ko00000 - - - Ala_racemase_N k141_1926_4 1116375.VEJY3_13460 5.51e-175 490.0 COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,1RNQK@1236|Gammaproteobacteria,1XSBY@135623|Vibrionales 135623|Vibrionales E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline proC - 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 - - - F420_oxidored,P5CR_dimer k141_1926_5 1116375.VEJY3_13465 8.21e-118 338.0 COG0762@1|root,COG0762@2|Bacteria,1RCZV@1224|Proteobacteria,1S6DW@1236|Gammaproteobacteria,1XTKT@135623|Vibrionales 135623|Vibrionales S Integral membrane protein yggT - - ko:K02221 - - - - ko00000,ko02044 - - - YGGT k141_8106_1 637389.Acaty_c0946 2.1e-11 67.8 COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,1RN6I@1236|Gammaproteobacteria,2NCFE@225057|Acidithiobacillales 225057|Acidithiobacillales H Involved in the biosynthesis of porphyrin-containing compound - - - - - - - - - - - - HemN_C,Radical_SAM k141_16594_1 1294265.JCM21738_920 2.01e-108 328.0 COG0488@1|root,COG0488@2|Bacteria,1TQNA@1239|Firmicutes,4H9VW@91061|Bacilli,1ZBZP@1386|Bacillus 91061|Bacilli S ABC transporter expZ - - ko:K18231 ko02010,map02010 - - - br01600,ko00000,ko00001,ko01504,ko02000 3.A.1.121.1,3.A.1.121.3 - - ABC_tran,ABC_tran_Xtn k141_37905_1 1196031.ALEG01000042_gene2318 1.46e-62 200.0 COG2323@1|root,COG2323@2|Bacteria,1V3N6@1239|Firmicutes,4HDTW@91061|Bacilli,1ZEJR@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF421) - - - - - - - - - - - - DUF421 k141_37905_2 218284.CCDN010000001_gene1393 5.31e-82 254.0 COG2309@1|root,COG2309@2|Bacteria,1TP65@1239|Firmicutes,4H9W8@91061|Bacilli,1ZCU3@1386|Bacillus 91061|Bacilli E COG2309 Leucyl aminopeptidase (aminopeptidase T) - - - ko:K19689 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M29 k141_36592_1 218284.CCDN010000001_gene957 4.88e-122 358.0 2C2CG@1|root,2Z7PW@2|Bacteria,1TQQ2@1239|Firmicutes,4H9UX@91061|Bacilli,1ZCFI@1386|Bacillus 91061|Bacilli S stage III sporulation protein AE spoIIIAE - - ko:K06394 - - - - ko00000 - - - Spore_III_AE k141_33208_1 1294265.JCM21738_2185 2.49e-107 310.0 COG0431@1|root,COG0431@2|Bacteria,1TPDX@1239|Firmicutes,4HE2D@91061|Bacilli,1ZFTZ@1386|Bacillus 91061|Bacilli S FMN reductase - - 1.5.1.38 ko:K00299 ko00740,ko00920,ko01100,map00740,map00920,map01100 - R05706,R07210,R10206 RC00126,RC01779,RC02556 ko00000,ko00001,ko01000 - - - FMN_red k141_28330_2 218284.CCDN010000001_gene510 2.54e-46 155.0 COG2186@1|root,COG2186@2|Bacteria,1V3Z4@1239|Firmicutes,4HG61@91061|Bacilli,1ZQ57@1386|Bacillus 91061|Bacilli K helix_turn_helix gluconate operon transcriptional repressor lutR_1 - - ko:K05799 - - - - ko00000,ko03000 - - - FCD,GntR k141_16626_1 1042377.AFPJ01000014_gene1666 4.93e-105 312.0 2ACR0@1|root,312BP@2|Bacteria,1NG36@1224|Proteobacteria,1SH59@1236|Gammaproteobacteria,46BQC@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_16626_2 1042377.AFPJ01000014_gene1667 5.61e-200 568.0 28J16@1|root,2Z8Y7@2|Bacteria,1R657@1224|Proteobacteria,1SFYP@1236|Gammaproteobacteria,46BM2@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_16626_3 1117319.PSPO_01725 1.2e-86 262.0 COG1266@1|root,COG1266@2|Bacteria,1RFHC@1224|Proteobacteria,1RZYC@1236|Gammaproteobacteria,2PZCM@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria S CAAX protease self-immunity - - - - - - - - - - - - Abi k141_16626_5 1453501.JELR01000001_gene2966 3.94e-310 848.0 COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,1RMD8@1236|Gammaproteobacteria,4643J@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine miaB GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035597,GO:0035600,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360 2.8.4.3 ko:K06168 - - R10645,R10646,R10647 RC00003,RC00980,RC03221,RC03222 ko00000,ko01000,ko03016 - - - Radical_SAM,TRAM,UPF0004 k141_16626_6 1042377.AFPJ01000014_gene1670 5.73e-209 582.0 COG1702@1|root,COG1702@2|Bacteria,1MVDV@1224|Proteobacteria,1RP2Y@1236|Gammaproteobacteria,464W4@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG1702 Phosphate starvation-inducible protein PhoH ybeZ GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K06217 - - - - ko00000 - - - PhoH k141_16626_7 1453501.JELR01000001_gene2968 1.91e-73 225.0 COG0319@1|root,COG0319@2|Bacteria,1MZ67@1224|Proteobacteria,1S6BS@1236|Gammaproteobacteria,467I5@72275|Alteromonadaceae 1236|Gammaproteobacteria J Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ybeY GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - ko:K07042 - - - - ko00000,ko03009 - - - UPF0054 k141_16626_9 1279017.AQYJ01000024_gene975 7.66e-255 713.0 COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,1RM8M@1236|Gammaproteobacteria,46473@72275|Alteromonadaceae 1236|Gammaproteobacteria M Transfers the fatty acyl group on membrane lipoproteins lnt GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016021,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031224,GO:0031226,GO:0034645,GO:0036211,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576 - ko:K03820 - - - - ko00000,ko01000 - GT2 iEcSMS35_1347.EcSMS35_0678,iSbBS512_1146.SbBS512_E0590 CN_hydrolase k141_16626_11 1042377.AFPJ01000014_gene1674 1.24e-170 482.0 COG1090@1|root,COG1090@2|Bacteria,1MUB4@1224|Proteobacteria,1RN6A@1236|Gammaproteobacteria,465A2@72275|Alteromonadaceae 1236|Gammaproteobacteria S nucleoside-diphosphate sugar epimerase yfcH - - ko:K07071 - - - - ko00000 - - - DUF1731,Epimerase k141_16626_12 1279017.AQYJ01000024_gene972 1.2e-52 169.0 2C6YA@1|root,33M7P@2|Bacteria,1NJUZ@1224|Proteobacteria,1SJ0Y@1236|Gammaproteobacteria,46C67@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_16626_13 1042377.AFPJ01000014_gene1676 2.39e-120 351.0 COG1434@1|root,COG1434@2|Bacteria,1MVW8@1224|Proteobacteria,1S92A@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Conserved Protein - - - - - - - - - - - - DUF218 k141_17832_1 218284.CCDN010000007_gene3829 4.81e-140 398.0 COG1235@1|root,COG1235@2|Bacteria,1TQ8E@1239|Firmicutes,4HAKD@91061|Bacilli,1ZASY@1386|Bacillus 91061|Bacilli S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I vicX - 3.1.26.11 ko:K00784 ko03013,map03013 - - - ko00000,ko00001,ko01000,ko03016 - - - Lactamase_B,Lactamase_B_2 k141_31757_1 225937.HP15_1683 6.7e-46 152.0 COG3791@1|root,COG3791@2|Bacteria,1RCYS@1224|Proteobacteria,1S3X0@1236|Gammaproteobacteria,46C99@72275|Alteromonadaceae 1236|Gammaproteobacteria S Glutathione-dependent formaldehyde-activating enzyme - - - - - - - - - - - - GFA k141_31757_2 1042377.AFPJ01000015_gene1618 4.79e-101 298.0 28IPG@1|root,2Z8PF@2|Bacteria,1P8KM@1224|Proteobacteria,1RY74@1236|Gammaproteobacteria,466DF@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_31757_3 744980.TRICHSKD4_0411 4.82e-78 241.0 COG2761@1|root,COG2761@2|Bacteria,1NXUB@1224|Proteobacteria,2U1PN@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q dithiol-disulfide isomerase involved in polyketide biosynthesis - - - - - - - - - - - - DSBA k141_31757_4 1453501.JELR01000002_gene1019 3.73e-45 155.0 COG0730@1|root,COG0730@2|Bacteria,1MVY3@1224|Proteobacteria,1S21M@1236|Gammaproteobacteria,467A8@72275|Alteromonadaceae 1236|Gammaproteobacteria S Sulfite exporter TauE/SafE - - - ko:K07090 - - - - ko00000 - - - TauE k141_16627_1 1453501.JELR01000006_gene32 1.02e-92 290.0 COG3509@1|root,COG3509@2|Bacteria,1R66H@1224|Proteobacteria,1SZAS@1236|Gammaproteobacteria,466AM@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Esterase PHB depolymerase - - - - - - - - - - - - Esterase_phd k141_15308_1 1042377.AFPJ01000004_gene414 1.86e-111 328.0 COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1MWCC@1224|Proteobacteria,1RNGC@1236|Gammaproteobacteria,465FU@72275|Alteromonadaceae 1236|Gammaproteobacteria K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon birA GO:0000166,GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004077,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009305,GO:0009374,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0017053,GO:0017076,GO:0017144,GO:0018130,GO:0018271,GO:0019538,GO:0019752,GO:0019842,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032991,GO:0033218,GO:0033293,GO:0034641,GO:0035639,GO:0036094,GO:0036211,GO:0042364,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043565,GO:0043603,GO:0043604,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681,GO:1990837 6.3.4.15 ko:K03524 ko00780,ko01100,map00780,map01100 - R01074,R05145 RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko01000,ko03000 - - - BPL_C,BPL_LplA_LipB,HTH_11 k141_30636_1 1196028.ALEF01000033_gene1326 9.2e-57 182.0 COG1309@1|root,COG1309@2|Bacteria,1V89E@1239|Firmicutes,4HH86@91061|Bacilli,4C6T1@84406|Virgibacillus 91061|Bacilli K Transcriptional regulator C-terminal region - - - - - - - - - - - - TetR_C_8,TetR_N k141_8173_1 42565.FP66_11975 8.43e-65 202.0 COG3501@1|root,COG3501@2|Bacteria,1MU7Q@1224|Proteobacteria,1RMZS@1236|Gammaproteobacteria,1XIYM@135619|Oceanospirillales 135619|Oceanospirillales M Rhs element Vgr protein - - - ko:K11904 ko03070,map03070 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - Phage_GPD k141_8173_2 768066.HELO_2908 8.3e-41 136.0 COG4104@1|root,COG4104@2|Bacteria,1RI2B@1224|Proteobacteria,1S65G@1236|Gammaproteobacteria 1236|Gammaproteobacteria S PAAR motif - - - - - - - - - - - - PAAR_motif k141_17833_2 768066.HELO_4398 1.72e-25 108.0 COG0270@1|root,COG0270@2|Bacteria,1MV9H@1224|Proteobacteria,1RYG6@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k141_31758_1 1169144.KB910931_gene974 4.92e-64 206.0 COG1680@1|root,COG1680@2|Bacteria,1TYVU@1239|Firmicutes,4HE5K@91061|Bacilli,1ZCMW@1386|Bacillus 91061|Bacilli V Beta-lactamase - - - - - - - - - - - - Beta-lactamase k141_33265_1 218284.CCDN010000001_gene807 2.59e-21 96.3 COG2866@1|root,COG2866@2|Bacteria,1TP3K@1239|Firmicutes,4HAHN@91061|Bacilli,1ZD1J@1386|Bacillus 91061|Bacilli E Gamma-D-glutamyl-L-diamino acid endopeptidase yqgT GO:0003674,GO:0003824,GO:0004180,GO:0004181,GO:0005575,GO:0005576,GO:0005615,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0044421,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.19.11 ko:K01308 - - - - ko00000,ko01000,ko01002 - - - LysM,Peptidase_M14 k141_36640_4 1279017.AQYJ01000028_gene2086 3.11e-95 291.0 COG2831@1|root,COG2831@2|Bacteria,1QW38@1224|Proteobacteria,1T2R4@1236|Gammaproteobacteria,464F6@72275|Alteromonadaceae 1236|Gammaproteobacteria U Protein of unknown function (DUF3570) - - - - - - - - - - - - DUF3570 k141_3516_1 1266925.JHVX01000009_gene143 9.79e-33 123.0 COG0082@1|root,COG0082@2|Bacteria,1MU98@1224|Proteobacteria,2VJA4@28216|Betaproteobacteria,37234@32003|Nitrosomonadales 28216|Betaproteobacteria E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system aroC - 4.2.3.5 ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01714 RC00586 ko00000,ko00001,ko00002,ko01000 - - - Chorismate_synt k141_3516_2 1279017.AQYJ01000024_gene1191 6.9e-188 526.0 COG2890@1|root,COG2890@2|Bacteria,1MX8Q@1224|Proteobacteria,1RPHQ@1236|Gammaproteobacteria,464PR@72275|Alteromonadaceae 1236|Gammaproteobacteria J Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue prmB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006304,GO:0006305,GO:0006306,GO:0006464,GO:0006479,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009007,GO:0009008,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0032775,GO:0034641,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044728,GO:0046483,GO:0071704,GO:0090304,GO:0140096,GO:0140097,GO:1901360,GO:1901564 2.1.1.298 ko:K07320 - - R10806 RC00003,RC03279 ko00000,ko01000,ko03009 - - - MTS k141_3516_3 1453501.JELR01000001_gene1822 5.6e-113 325.0 COG0302@1|root,COG0302@2|Bacteria,1MY3N@1224|Proteobacteria,1RMQM@1236|Gammaproteobacteria,463YM@72275|Alteromonadaceae 1236|Gammaproteobacteria H GTP cyclohydrolase I folE GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 ko:K01495 ko00790,ko01100,map00790,map01100 M00126,M00841,M00842,M00843 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 - - - GTP_cyclohydroI k141_3516_5 1279017.AQYJ01000024_gene1188 1.02e-135 392.0 COG0596@1|root,COG0596@2|Bacteria,1QTWQ@1224|Proteobacteria,1T1JQ@1236|Gammaproteobacteria,46DBF@72275|Alteromonadaceae 1236|Gammaproteobacteria S Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 k141_3516_6 1279017.AQYJ01000024_gene1187 4.83e-73 222.0 COG2062@1|root,COG2062@2|Bacteria,1RG7G@1224|Proteobacteria,1RTH3@1236|Gammaproteobacteria,468NQ@72275|Alteromonadaceae 1236|Gammaproteobacteria T phosphohistidine phosphatase, SixA - - - ko:K08296 - - - - ko00000,ko01000 - - - His_Phos_1 k141_3516_7 1042377.AFPJ01000037_gene3015 1.02e-54 179.0 2E80T@1|root,332F0@2|Bacteria,1N7RY@1224|Proteobacteria,1SCE8@1236|Gammaproteobacteria,467UH@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF4389) - - - - - - - - - - - - DUF4389 k141_17834_1 1274524.BSONL12_10426 4.72e-101 306.0 COG4408@1|root,COG4408@2|Bacteria,1V010@1239|Firmicutes,4HFD3@91061|Bacilli,1ZM57@1386|Bacillus 91061|Bacilli S Staphylopine dehydrogenase - - - - - - - - - - - - Staph_opine_DH k141_8175_1 1163671.JAGI01000002_gene3759 4.15e-17 76.3 2EBGV@1|root,335HF@2|Bacteria,1UPVS@1239|Firmicutes,24VUQ@186801|Clostridia 186801|Clostridia S COG NOG38524 non supervised orthologous group - - - - - - - - - - - - - k141_33266_1 218284.CCDN010000002_gene2907 1.34e-233 658.0 COG0753@1|root,COG0753@2|Bacteria,1TPPV@1239|Firmicutes,4H9XQ@91061|Bacilli,1ZB44@1386|Bacillus 91061|Bacilli P serves to protect cells from the toxic effects of hydrogen peroxide katE GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0042221,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070887,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1990748 1.11.1.6 ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 M00532 R00009,R00602,R02670 RC00034,RC00767,RC02141,RC02755 ko00000,ko00001,ko00002,ko01000 - - - Catalase,Catalase-rel,DJ-1_PfpI k141_4732_2 218284.CCDN010000005_gene3498 6.73e-44 146.0 COG1247@1|root,COG1247@2|Bacteria,1VAAC@1239|Firmicutes,4HKUR@91061|Bacilli,1ZHWJ@1386|Bacillus 91061|Bacilli M FR47-like protein - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10,FR47 k141_28387_1 218284.CCDN010000006_gene3637 3.12e-05 44.7 COG0139@1|root,COG0140@1|root,COG0139@2|Bacteria,COG0140@2|Bacteria,1UYNA@1239|Firmicutes,4HA9R@91061|Bacilli,1ZDBB@1386|Bacillus 91061|Bacilli E belongs to the PRA-CH family hisI - 3.5.4.19,3.6.1.31 ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035,R04037 RC00002,RC01055 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS14110,iYO844.BSU34860 PRA-CH,PRA-PH k141_28387_2 218284.CCDN010000006_gene3636 2.66e-152 441.0 COG0457@1|root,COG0457@2|Bacteria,1UBH2@1239|Firmicutes,4HB47@91061|Bacilli,1ZD40@1386|Bacillus 91061|Bacilli S COG0457 FOG TPR repeat yvcD - - - - - - - - - - - HTH_psq,TPR_16,TPR_19,TPR_2,TPR_8 k141_33267_1 1042377.AFPJ01000024_gene818 3.75e-114 340.0 COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,1RMS3@1236|Gammaproteobacteria,464X1@72275|Alteromonadaceae 1236|Gammaproteobacteria CH COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases ubiH GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008681,GO:0009058,GO:0009108,GO:0009314,GO:0009416,GO:0009628,GO:0009987,GO:0016491,GO:0016705,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0050896,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901576,GO:1901661,GO:1901663 - ko:K03185,ko:K18800 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04987,R04989,R08768,R08773 RC00046,RC02670 ko00000,ko00001,ko00002,ko01000 - - iB21_1397.B21_02702,iECBD_1354.ECBD_0830,iECB_1328.ECB_02739,iECD_1391.ECD_02739,iEcHS_1320.EcHS_A3066 FAD_binding_3 k141_2348_1 1121939.L861_22685 4.41e-173 486.0 COG1718@1|root,COG1718@2|Bacteria,1MXY2@1224|Proteobacteria,1RND1@1236|Gammaproteobacteria,1XHD7@135619|Oceanospirillales 135619|Oceanospirillales DT COG1718 Serine threonine protein kinase involved in cell cycle control - - 2.7.11.1 ko:K07178 ko03008,map03008 - - - ko00000,ko00001,ko01000,ko01001,ko03009 - - - RIO1 k141_21341_1 223926.28808615 4.73e-109 334.0 COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,1RSP9@1236|Gammaproteobacteria,1XXZ7@135623|Vibrionales 135623|Vibrionales O Subtilase family - - - - - - - - - - - - Peptidase_S8 k141_3520_1 1121938.AUDY01000008_gene1922 9.76e-86 264.0 COG1301@1|root,COG1301@2|Bacteria,1TP4N@1239|Firmicutes,4HAUP@91061|Bacilli,3NFT8@45667|Halobacillus 91061|Bacilli C Sodium:dicarboxylate symporter family dctP - - - - - - - - - - - SDF k141_36645_1 260799.BAS4482 2.25e-13 68.9 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,4H9S7@91061|Bacilli,1ZB6Y@1386|Bacillus 91061|Bacilli L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A k141_21343_1 1294265.JCM21738_447 3.52e-81 242.0 COG1023@1|root,COG1023@2|Bacteria,1UHN4@1239|Firmicutes,4IS44@91061|Bacilli,1ZS1B@1386|Bacillus 91061|Bacilli G 6-phosphogluconate dehydrogenase yqeC - 1.1.1.343,1.1.1.44 ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 M00004,M00006 R01528,R10221 RC00001,RC00539 ko00000,ko00001,ko00002,ko01000 - - - 6PGD,NAD_binding_2 k141_21343_2 1294265.JCM21738_446 2.03e-14 71.2 COG1737@1|root,COG1737@2|Bacteria,1TR0N@1239|Firmicutes,4HB9E@91061|Bacilli,1ZCCD@1386|Bacillus 91061|Bacilli K RpiR family transcriptional regulator gntR - - - - - - - - - - - HTH_6,SIS k141_31761_1 441769.ABFU01000057_gene809 4.16e-91 280.0 COG1511@1|root,COG1511@2|Bacteria,1TRMJ@1239|Firmicutes,4HB2N@91061|Bacilli,1ZBC1@1386|Bacillus 91061|Bacilli S domain protein - - - - - - - - - - - - - k141_33268_3 218284.CCDN010000006_gene3626 5.61e-11 63.9 COG0745@1|root,COG2199@1|root,COG0745@2|Bacteria,COG3706@2|Bacteria,1TSW8@1239|Firmicutes,4HBT1@91061|Bacilli,1ZCZQ@1386|Bacillus 91061|Bacilli T diguanylate cyclase - - - - - - - - - - - - GGDEF,Hpt,Response_reg k141_36646_1 666686.B1NLA3E_17160 6.31e-26 99.4 COG2707@1|root,COG2707@2|Bacteria,1VBA7@1239|Firmicutes,4HKC9@91061|Bacilli,1ZG6J@1386|Bacillus 91061|Bacilli S Membrane - - - - - - - - - - - - DUF441 k141_36646_2 1294265.JCM21738_4695 5.62e-73 221.0 COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,4H9YE@91061|Bacilli,1ZBAY@1386|Bacillus 91061|Bacilli C Belongs to the citrate synthase family citZ - 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 - - - Citrate_synt k141_4734_1 218284.CCDN010000001_gene206 2.74e-221 615.0 COG1721@1|root,COG1721@2|Bacteria,1U0JI@1239|Firmicutes,4HDNW@91061|Bacilli,1ZDIV@1386|Bacillus 91061|Bacilli S Protein of unknown function DUF58 - - - - - - - - - - - - DUF58 k141_4734_2 218284.CCDN010000001_gene207 4.1e-134 385.0 COG0714@1|root,COG0714@2|Bacteria,1TPKR@1239|Firmicutes,4HA0T@91061|Bacilli,1ZCN3@1386|Bacillus 91061|Bacilli S ATPase family associated with various cellular activities (AAA) - - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 k141_16630_1 1279017.AQYJ01000026_gene111 8.57e-253 711.0 COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,1SYC8@1236|Gammaproteobacteria,46AMB@72275|Alteromonadaceae 1236|Gammaproteobacteria P Sulfate permease family - - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - STAS,Sulfate_transp k141_16630_2 1279017.AQYJ01000026_gene110 3.15e-59 187.0 COG2391@1|root,COG2391@2|Bacteria,1MZC0@1224|Proteobacteria,1S8UB@1236|Gammaproteobacteria,467VW@72275|Alteromonadaceae 1236|Gammaproteobacteria S Transporter component - - - ko:K07112 - - - - ko00000 - - - Sulf_transp k141_16630_3 95619.PM1_0219925 4.38e-64 199.0 COG2391@1|root,COG2391@2|Bacteria,1MZ3A@1224|Proteobacteria,1S95T@1236|Gammaproteobacteria 1236|Gammaproteobacteria E transporter component - - - ko:K07112 - - - - ko00000 - - - Sulf_transp k141_21344_1 218284.CCDN010000001_gene1061 5.78e-259 718.0 COG1333@1|root,COG1333@2|Bacteria,1TQ6C@1239|Firmicutes,4HAFD@91061|Bacilli,1ZBB3@1386|Bacillus 91061|Bacilli O COG1333 ResB protein required for cytochrome c biosynthesis resB - - ko:K07399 - - - - ko00000 - - - ResB k141_16631_1 1453501.JELR01000001_gene2829 1.04e-87 276.0 COG2272@1|root,COG2272@2|Bacteria,1MVQZ@1224|Proteobacteria,1RPFW@1236|Gammaproteobacteria,465DX@72275|Alteromonadaceae 1236|Gammaproteobacteria I Carboxylesterase family estA1 - - ko:K03929 - - - - ko00000,ko01000 - CE10 - COesterase k141_36726_2 1453501.JELR01000002_gene1323 2.19e-89 278.0 COG0810@1|root,COG0810@2|Bacteria,1R65W@1224|Proteobacteria,1S133@1236|Gammaproteobacteria,466F5@72275|Alteromonadaceae 1236|Gammaproteobacteria M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - - - - - - - - - - - k141_36726_3 1042377.AFPJ01000028_gene2168 3.45e-69 214.0 COG0848@1|root,COG0848@2|Bacteria,1RENY@1224|Proteobacteria,1S3TB@1236|Gammaproteobacteria,4681G@72275|Alteromonadaceae 1236|Gammaproteobacteria U Biopolymer transport protein ExbD/TolR - - - - - - - - - - - - ExbD k141_36726_4 1279017.AQYJ01000028_gene2070 1.97e-74 228.0 COG0848@1|root,COG0848@2|Bacteria,1RHI8@1224|Proteobacteria,1S6FK@1236|Gammaproteobacteria,467HF@72275|Alteromonadaceae 1236|Gammaproteobacteria U COG0848 Biopolymer transport protein - - - - - - - - - - - - ExbD k141_36726_5 1279017.AQYJ01000028_gene2071 3.85e-111 324.0 COG0811@1|root,COG0811@2|Bacteria,1PKF8@1224|Proteobacteria,1RRWP@1236|Gammaproteobacteria,465RQ@72275|Alteromonadaceae 1236|Gammaproteobacteria U COG0811 Biopolymer transport proteins aglR - - - - - - - - - - - MotA_ExbB k141_36726_6 1042377.AFPJ01000028_gene2165 4.2e-22 89.7 2DRME@1|root,33C9X@2|Bacteria,1NHQS@1224|Proteobacteria,1SH9S@1236|Gammaproteobacteria,468YE@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_36726_7 1042377.AFPJ01000028_gene2164 1.6e-43 152.0 COG0457@1|root,COG0457@2|Bacteria,1NB8N@1224|Proteobacteria,1SEZN@1236|Gammaproteobacteria,4683W@72275|Alteromonadaceae 1236|Gammaproteobacteria S TPR repeat - - - - - - - - - - - - TPR_1,TPR_10,TPR_12,TPR_16,TPR_2,TPR_6,TPR_8 k141_36726_8 1453501.JELR01000002_gene1329 2.82e-79 262.0 COG4105@1|root,COG4105@2|Bacteria,1QVQ9@1224|Proteobacteria,1RSIG@1236|Gammaproteobacteria,46DC5@72275|Alteromonadaceae 1236|Gammaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16,TPR_6 k141_37989_2 1453501.JELR01000002_gene1234 4.22e-26 107.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPES@1236|Gammaproteobacteria,464G8@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0488 ATPase components of ABC transporters with duplicated ATPase domains yheS GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K06158 - - - - ko00000,ko03012 - - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn k141_36727_2 218284.CCDN010000002_gene2122 7.77e-160 454.0 COG0473@1|root,COG0473@2|Bacteria,1TPEM@1239|Firmicutes,4HATP@91061|Bacilli,1ZB3Y@1386|Bacillus 91061|Bacilli CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate leuB GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R00994,R04426,R10052 RC00084,RC00417,RC03036 br01601,ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU28270 Iso_dh k141_37990_1 1131730.BAVI_25220 7.15e-127 373.0 COG0172@1|root,COG0172@2|Bacteria,1TP4W@1239|Firmicutes,4H9Y4@91061|Bacilli,1ZCBQ@1386|Bacillus 91061|Bacilli J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) serS - 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Seryl_tRNA_N,tRNA-synt_2b k141_30701_2 1214065.BAGV01000009_gene3324 1.29e-29 120.0 2DKWI@1|root,30M97@2|Bacteria,1RF1H@1224|Proteobacteria,1S4VV@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF4349) - - - - - - - - - - - - DUF4349 k141_30701_3 1279017.AQYJ01000021_gene2822 1.55e-134 386.0 COG3118@1|root,COG3118@2|Bacteria,1MV0R@1224|Proteobacteria,1RMSQ@1236|Gammaproteobacteria,4641J@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG3118 Thioredoxin domain-containing protein ybbN GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0008150,GO:0008152,GO:0009987,GO:0015035,GO:0015036,GO:0016491,GO:0016667,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0061077 - ko:K03671,ko:K05838 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - TPR_19,TPR_20,Thioredoxin k141_36729_1 935836.JAEL01000020_gene984 1.02e-126 364.0 COG2267@1|root,COG2267@2|Bacteria,1V4PE@1239|Firmicutes,4ISRY@91061|Bacilli,1ZS9Z@1386|Bacillus 91061|Bacilli I Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_1,Hydrolase_4 k141_8231_1 218284.CCDN010000001_gene1920 3.1e-111 327.0 COG1868@1|root,COG1868@2|Bacteria,1TPTM@1239|Firmicutes,4HAAY@91061|Bacilli,1ZCI6@1386|Bacillus 91061|Bacilli N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation fliM GO:0005575,GO:0005623,GO:0005886,GO:0006935,GO:0008150,GO:0009288,GO:0009425,GO:0009605,GO:0016020,GO:0040011,GO:0042221,GO:0042330,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0050896,GO:0050918,GO:0071944 - ko:K02416 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02035 - - - FliM,FliMN_C k141_28465_2 498211.CJA_1083 8.33e-122 360.0 COG2273@1|root,COG2273@2|Bacteria,1R70T@1224|Proteobacteria,1RSIR@1236|Gammaproteobacteria,1FGMA@10|Cellvibrio 1236|Gammaproteobacteria G Hydrolase Family 16 - - - - - - - - - - - - Glyco_hydro_16 k141_28465_3 1042377.AFPJ01000034_gene2379 2.04e-212 592.0 COG4299@1|root,COG4299@2|Bacteria,1R5FB@1224|Proteobacteria,1S1E0@1236|Gammaproteobacteria,467VN@72275|Alteromonadaceae 1236|Gammaproteobacteria S COGs COG4299 conserved - - - - - - - - - - - - DUF1624,DUF5009 k141_28465_5 1279017.AQYJ01000023_gene3148 8.58e-130 375.0 COG0491@1|root,COG0491@2|Bacteria 2|Bacteria GM Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - - - - - - - - - - Lactamase_B k141_36731_1 1042377.AFPJ01000048_gene2685 3.8e-53 189.0 COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,1RSKR@1236|Gammaproteobacteria,46CIZ@72275|Alteromonadaceae 1236|Gammaproteobacteria KLT Lipopolysaccharide kinase (Kdo/WaaP) family - - 2.7.11.1 ko:K08884,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - Pkinase,TPR_16,TPR_19,TPR_2,TPR_8 k141_28467_1 218284.CCDN010000011_gene4425 4.58e-101 304.0 COG2252@1|root,COG2252@2|Bacteria,1TQC6@1239|Firmicutes,4HANG@91061|Bacilli,1ZARH@1386|Bacillus 91061|Bacilli S permease pbuG - - ko:K06901 - - - - ko00000,ko02000 2.A.1.40 - iYO844.BSU06370 Xan_ur_permease k141_8232_1 1453501.JELR01000001_gene2856 1.96e-68 230.0 COG1472@1|root,COG1472@2|Bacteria,1MVIV@1224|Proteobacteria,1RMA0@1236|Gammaproteobacteria,465BV@72275|Alteromonadaceae 1236|Gammaproteobacteria G Family 3 - - 3.2.1.21 ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 - R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - GH3 - Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C,Lipase_GDSL_2 k141_8232_2 1122194.AUHU01000015_gene3035 4.13e-16 80.9 COG1472@1|root,COG1472@2|Bacteria,1MVIV@1224|Proteobacteria,1RMA0@1236|Gammaproteobacteria,465BV@72275|Alteromonadaceae 1236|Gammaproteobacteria G Family 3 - - 3.2.1.21 ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 - R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - GH3 - Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C k141_36733_2 218284.CCDN010000002_gene2055 8.49e-63 207.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4H9SC@91061|Bacilli,1ZBEE@1386|Bacillus 91061|Bacilli V ABC transporter malQ - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran k141_8234_1 218284.CCDN010000001_gene1173 7.04e-52 185.0 COG0699@1|root,COG0699@2|Bacteria,1TR0Q@1239|Firmicutes,4HBAC@91061|Bacilli,1ZAXM@1386|Bacillus 91061|Bacilli S Dynamin family ypbR GO:0000910,GO:0003674,GO:0003824,GO:0003924,GO:0005575,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022402,GO:0022607,GO:0031224,GO:0032506,GO:0044085,GO:0044425,GO:0051301,GO:0071840,GO:0090529 - - - - - - - - - - Dynamin_N k141_8235_1 42565.FP66_09830 3.76e-46 151.0 COG1327@1|root,COG1327@2|Bacteria,1RE7V@1224|Proteobacteria,1S3P9@1236|Gammaproteobacteria,1XJKR@135619|Oceanospirillales 135619|Oceanospirillales K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes nrdR - - ko:K07738 - - - - ko00000,ko03000 - - - ATP-cone k141_8235_2 42565.FP66_09825 1.91e-25 100.0 COG1651@1|root,COG1651@2|Bacteria,1NEFD@1224|Proteobacteria,1RQAW@1236|Gammaproteobacteria,1XMWA@135619|Oceanospirillales 135619|Oceanospirillales O Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process dsbG - - ko:K03805 - - - - ko00000,ko03110 - - - Thioredoxin_2 k141_18046_1 218284.CCDN010000008_gene4223 1.1e-81 261.0 COG0849@1|root,COG0849@2|Bacteria,1TP1Z@1239|Firmicutes,4HBAG@91061|Bacilli,1ZBRW@1386|Bacillus 91061|Bacilli D Cell division protein FtsA ftsA_1 - - - - - - - - - - - FtsA,PilM_2 k141_12031_2 642492.Clole_3383 1.12e-15 74.3 COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,24FR4@186801|Clostridia 186801|Clostridia F Belongs to the purine pyrimidine phosphoribosyltransferase family hpt - 2.4.2.8 ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 - R00190,R01132,R01229,R02142,R08237,R08238,R08245 RC00063,RC00122 ko00000,ko00001,ko01000 - - - Pribosyltran k141_34644_1 218284.CCDN010000002_gene2876 1.06e-232 649.0 COG0471@1|root,COG0471@2|Bacteria,1UPY0@1239|Firmicutes,4HF0U@91061|Bacilli,1ZEY0@1386|Bacillus 91061|Bacilli P Sodium:sulfate symporter transmembrane region citT_2 - - - - - - - - - - - Na_sulph_symp k141_21600_1 1116375.VEJY3_13945 6.12e-185 529.0 COG0369@1|root,COG0369@2|Bacteria,1QUAH@1224|Proteobacteria,1T1RJ@1236|Gammaproteobacteria,1XT6J@135623|Vibrionales 135623|Vibrionales P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component cysJ - 1.8.1.2 ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00176 R00858 RC00065 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_1,Flavodoxin_1,NAD_binding_1 k141_223_2 1532558.JL39_10500 1.05e-47 157.0 COG0517@1|root,COG0517@2|Bacteria,1Q3MP@1224|Proteobacteria,2UB19@28211|Alphaproteobacteria,4BMRJ@82115|Rhizobiaceae 28211|Alphaproteobacteria S Domain in cystathionine beta-synthase and other proteins. - - - - - - - - - - - - CBS k141_7289_1 1007103.AFHW01000174_gene2483 6.52e-54 177.0 COG0745@1|root,COG0745@2|Bacteria,1TSWT@1239|Firmicutes,4HBSC@91061|Bacilli,26S4H@186822|Paenibacillaceae 91061|Bacilli T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - - - - - - - - - - Response_reg,Trans_reg_C k141_14445_1 42565.FP66_10845 8.52e-24 95.1 COG0693@1|root,COG0693@2|Bacteria,1MVTT@1224|Proteobacteria,1RPVK@1236|Gammaproteobacteria,1XIB3@135619|Oceanospirillales 135619|Oceanospirillales S ThiJ PfpI - - - - - - - - - - - - DJ-1_PfpI k141_14445_2 42565.FP66_10840 2.19e-80 243.0 COG4221@1|root,COG4221@2|Bacteria,1MUF8@1224|Proteobacteria,1RMKM@1236|Gammaproteobacteria,1XH79@135619|Oceanospirillales 135619|Oceanospirillales S Belongs to the short-chain dehydrogenases reductases (SDR) family - - 1.1.1.313,1.1.1.381 ko:K15373,ko:K16066 ko00240,ko00260,ko00430,ko01100,map00240,map00260,map00430,map01100 - R02600,R09289,R10851,R10852 RC00087,RC00525,RC03288 ko00000,ko00001,ko01000 - - - adh_short k141_28735_1 218284.CCDN010000001_gene1055 7.35e-116 334.0 COG1386@1|root,COG1386@2|Bacteria,1V6HI@1239|Firmicutes,4HIQ0@91061|Bacilli,1ZFNU@1386|Bacillus 91061|Bacilli D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves scpB GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K06024 - - - - ko00000,ko03036 - - - SMC_ScpB k141_35776_1 1294265.JCM21738_4457 6.37e-73 221.0 COG3881@1|root,COG3881@2|Bacteria,1VEG9@1239|Firmicutes,4HPBU@91061|Bacilli,1ZH8E@1386|Bacillus 91061|Bacilli S protein conserved in bacteria yrrD - - - - - - - - - - - PRC k141_8508_1 1117647.M5M_16815 2.72e-165 492.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MWS3@1224|Proteobacteria,1RPG6@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Outer membrane receptor proteins mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec k141_34645_1 218284.CCDN010000002_gene2747 1.47e-82 255.0 COG0860@1|root,COG5632@1|root,COG0860@2|Bacteria,COG5632@2|Bacteria,1UYW5@1239|Firmicutes,4HF0Y@91061|Bacilli,1ZGSJ@1386|Bacillus 91061|Bacilli M N-acetylmuramoyl-L-alanine amidase - - - - - - - - - - - - - k141_15650_2 1294265.JCM21738_4028 4.66e-69 209.0 COG4839@1|root,COG4839@2|Bacteria,1VDUV@1239|Firmicutes,4HKM7@91061|Bacilli,1ZIVC@1386|Bacillus 91061|Bacilli D Essential cell division protein ftsL - - - - - - - - - - - DivIC k141_15650_3 1294265.JCM21738_4029 8.94e-57 191.0 COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,4H9VQ@91061|Bacilli,1ZASE@1386|Bacillus 91061|Bacilli M Penicillin-binding Protein pbpX GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - - PASTA,PBP_dimer,Transpeptidase k141_6161_1 42565.FP66_08975 1.65e-37 131.0 COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,1RNWR@1236|Gammaproteobacteria,1XH9P@135619|Oceanospirillales 135619|Oceanospirillales C SdhA B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC D which are the membrane components and form cytochrome b556 sdhB - 1.3.5.1,1.3.5.4 ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - Fer2_3,Fer4_17 k141_6161_2 42565.FP66_08980 6.01e-203 574.0 COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,1RMU2@1236|Gammaproteobacteria,1XIK9@135619|Oceanospirillales 135619|Oceanospirillales C Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily sdhA - 1.3.5.1,1.3.5.4 ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C k141_18047_1 218284.CCDN010000001_gene131 5.31e-112 328.0 COG1612@1|root,COG1612@2|Bacteria,1TR4W@1239|Firmicutes,4HC12@91061|Bacilli,1ZC0K@1386|Bacillus 91061|Bacilli O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group ctaA GO:0000003,GO:0003674,GO:0003824,GO:0008150,GO:0009987,GO:0016043,GO:0017004,GO:0019954,GO:0022607,GO:0030436,GO:0032502,GO:0034622,GO:0043933,GO:0043934,GO:0044085,GO:0065003,GO:0071840 - ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 M00154 R07412 RC00769 ko00000,ko00001,ko00002,ko03029 3.D.4.4 - iSB619.SA_RS05460,iYO844.BSU14870 COX15-CtaA k141_20320_1 42565.FP66_04280 6.32e-127 364.0 COG2949@1|root,COG2949@2|Bacteria,1MURW@1224|Proteobacteria,1RMG7@1236|Gammaproteobacteria,1XKSR@135619|Oceanospirillales 135619|Oceanospirillales S DUF218 domain sanA - - ko:K03748 - - - - ko00000 - - - DUF218 k141_20320_2 42565.FP66_04275 1.3e-64 200.0 COG2151@1|root,COG2151@2|Bacteria,1MZ9Y@1224|Proteobacteria,1S36X@1236|Gammaproteobacteria,1XJRA@135619|Oceanospirillales 135619|Oceanospirillales S FeS assembly SUF system protein SufT - - - - - - - - - - - - FeS_assembly_P k141_21601_1 1232683.ADIMK_2559 1.3e-57 192.0 COG1167@1|root,COG1167@2|Bacteria,1MV6F@1224|Proteobacteria,1RMQ0@1236|Gammaproteobacteria,465KT@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs - - - - - - - - - - - - Aminotran_1_2,GntR k141_9650_1 42565.FP66_05180 7.96e-94 280.0 COG1108@1|root,COG1108@2|Bacteria,1MVC2@1224|Proteobacteria,1RRX3@1236|Gammaproteobacteria,1XI6B@135619|Oceanospirillales 135619|Oceanospirillales P ABC transporter permease - - - ko:K02075,ko:K11606 ko02010,map02010 M00244,M00317 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15,3.A.1.15.7,3.A.1.15.9 - - ABC-3 k141_9650_2 42565.FP66_05185 3.07e-52 170.0 COG1121@1|root,COG1121@2|Bacteria,1MW47@1224|Proteobacteria,1S1N4@1236|Gammaproteobacteria 1236|Gammaproteobacteria P (ABC) transporter mntB - - ko:K02074 - M00244 - - ko00000,ko00002,ko02000 3.A.1.15 - - ABC_tran k141_31101_1 1116375.VEJY3_14405 1.88e-78 239.0 COG0697@1|root,COG0697@2|Bacteria,1R4G2@1224|Proteobacteria,1S1NT@1236|Gammaproteobacteria,1XTQV@135623|Vibrionales 135623|Vibrionales EG of the drug metabolite transporter (DMT) superfamily - - - - - - - - - - - - EamA k141_13264_2 1294265.JCM21738_4112 1.45e-119 343.0 COG5553@1|root,COG5553@2|Bacteria,1VFPC@1239|Firmicutes,4HPUH@91061|Bacilli,1ZFM7@1386|Bacillus 91061|Bacilli S Cysteine dioxygenase type I cdoA - 1.13.11.20 ko:K00456 ko00270,ko00430,ko01100,map00270,map00430,map01100 - R00893 RC00404 ko00000,ko00001,ko01000 - - - CDO_I k141_13264_3 1294265.JCM21738_4111 9.05e-07 49.7 COG0697@1|root,COG0697@2|Bacteria,1TRKE@1239|Firmicutes,4HF69@91061|Bacilli,1ZQ3B@1386|Bacillus 91061|Bacilli EG EamA-like transporter family - - - - - - - - - - - - EamA k141_27462_2 218284.CCDN010000007_gene3798 8.12e-140 398.0 COG0357@1|root,COG0357@2|Bacteria,1TPBT@1239|Firmicutes,4HAAZ@91061|Bacilli,1ZAWG@1386|Bacillus 91061|Bacilli J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA rsmG GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 ko:K03501 - - - - ko00000,ko01000,ko03009,ko03036 - - - GidB k141_14446_1 935837.JAEK01000054_gene1472 2.31e-54 190.0 2CH1R@1|root,33IF5@2|Bacteria,1VMK6@1239|Firmicutes,4HZT1@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - k141_33412_1 1453501.JELR01000002_gene1202 7.47e-265 729.0 COG3000@1|root,COG3000@2|Bacteria,1NR7X@1224|Proteobacteria,1RQDX@1236|Gammaproteobacteria,46582@72275|Alteromonadaceae 1236|Gammaproteobacteria I Sterol desaturase - - - - - - - - - - - - FA_hydroxylase k141_33412_2 1453501.JELR01000002_gene1201 1.59e-46 154.0 COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,1RN09@1236|Gammaproteobacteria,466I4@72275|Alteromonadaceae 1236|Gammaproteobacteria F Essential for recycling GMP and indirectly, cGMP gmk GO:0003674,GO:0003824,GO:0004385,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_2813,iPC815.YPO0040,iSBO_1134.SBO_3729,iSFV_1184.SFV_3881,iSFxv_1172.SFxv_4016,iUTI89_1310.UTI89_C4193 Guanylate_kin k141_1295_1 218284.CCDN010000001_gene1490 8.93e-215 608.0 COG0187@1|root,COG0187@2|Bacteria,1TQCF@1239|Firmicutes,4H9UC@91061|Bacilli,1ZBMM@1386|Bacillus 91061|Bacilli L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parE GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 - ko:K02622 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim k141_12032_1 218284.CCDN010000001_gene1233 4.89e-140 399.0 COG2865@1|root,COG2865@2|Bacteria,1V9FQ@1239|Firmicutes,4HXRR@91061|Bacilli,1ZEN7@1386|Bacillus 91061|Bacilli K Putative DNA-binding domain - - - - - - - - - - - - AlbA_2 k141_12032_2 1405.DJ92_3363 9.22e-06 49.7 COG1316@1|root,COG1316@2|Bacteria,1TSWQ@1239|Firmicutes,4HE66@91061|Bacilli,1ZBW5@1386|Bacillus 91061|Bacilli K COG1316 Transcriptional regulator psr - - - - - - - - - - - LytR_cpsA_psr k141_28736_1 1453501.JELR01000001_gene2936 1.67e-19 84.0 COG0431@1|root,COG0431@2|Bacteria,1RH7F@1224|Proteobacteria,1T04E@1236|Gammaproteobacteria,46872@72275|Alteromonadaceae 1236|Gammaproteobacteria S NADPH-dependent FMN reductase - - - ko:K19784 - - - - ko00000 - - - FMN_red k141_28736_2 1453501.JELR01000001_gene2935 5.26e-111 327.0 COG0583@1|root,COG0583@2|Bacteria,1MWVB@1224|Proteobacteria,1RZTS@1236|Gammaproteobacteria,468M2@72275|Alteromonadaceae 1236|Gammaproteobacteria K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_27463_1 218284.CCDN010000006_gene3745 5.32e-95 298.0 COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,4HAAG@91061|Bacilli,1ZPV2@1386|Bacillus 91061|Bacilli G Belongs to the glycosyl hydrolase 3 family bglX - 3.2.1.21,3.2.1.52 ko:K01207,ko:K05349 ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501 M00628 R00022,R00026,R02558,R02887,R02985,R03527,R04949,R04998,R05963,R07809,R07810,R10035,R10039,R10040,R10831 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko00002,ko01000 - GH3 - Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C k141_35777_2 218284.CCDN010000003_gene2976 1.75e-164 464.0 COG0030@1|root,COG0030@2|Bacteria,1TP9W@1239|Firmicutes,4HA4R@91061|Bacilli,1ZBZX@1386|Bacillus 91061|Bacilli J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits ksgA GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 ko:K02528 - - R10716 RC00003,RC03257 ko00000,ko01000,ko03009 - - - RrnaAD k141_34647_1 218284.CCDN010000001_gene118 5.2e-68 210.0 COG2050@1|root,COG2050@2|Bacteria,1VN0K@1239|Firmicutes,4HM66@91061|Bacilli,1ZHD4@1386|Bacillus 91061|Bacilli Q protein, possibly involved in aromatic compounds catabolism - - - ko:K02614 ko00360,map00360 - R09840 RC00004,RC00014 ko00000,ko00001,ko01000 - - - 4HBT k141_19150_1 1116375.VEJY3_19151 5.19e-140 401.0 COG0583@1|root,COG0583@2|Bacteria,1NZBS@1224|Proteobacteria,1SQGQ@1236|Gammaproteobacteria,1XVE0@135623|Vibrionales 135623|Vibrionales K COG0583 Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_1296_1 1042377.AFPJ01000023_gene671 1.43e-57 187.0 COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,1RR68@1236|Gammaproteobacteria,464NZ@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate moaA GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016829,GO:0016830,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0061798,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.22 ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09394 RC03420 ko00000,ko00001,ko01000 - - iSbBS512_1146.SbBS512_E2571,ic_1306.c0862 Fer4_12,Mob_synth_C,Radical_SAM k141_8509_1 218284.CCDN010000004_gene3029 1.08e-139 400.0 COG2208@1|root,COG2208@2|Bacteria,1TQY5@1239|Firmicutes,4HAF6@91061|Bacilli,1ZBIB@1386|Bacillus 91061|Bacilli KT phosphatase rsbU - 3.1.3.3 ko:K07315 - - - - ko00000,ko01000,ko03021 - - - RsbU_N,SpoIIE k141_28737_1 1294265.JCM21738_2060 9.06e-71 216.0 COG0209@1|root,COG0209@2|Bacteria,1TPFH@1239|Firmicutes,4HA07@91061|Bacilli,1ZCST@1386|Bacillus 91061|Bacilli F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen nrdA - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_lgC,Ribonuc_red_lgN k141_2563_1 1536774.H70357_10670 2.43e-37 146.0 COG5280@1|root,COG5412@1|root,COG5280@2|Bacteria,COG5412@2|Bacteria,1TQ28@1239|Firmicutes,4HGP4@91061|Bacilli,26UKE@186822|Paenibacillaceae 91061|Bacilli E minor tail protein - - - - - - - - - - - - PhageMin_Tail k141_34648_1 218284.CCDN010000001_gene659 5.06e-104 314.0 COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,4HAB7@91061|Bacilli,1ZDHC@1386|Bacillus 91061|Bacilli S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid spoVB - - ko:K06409 - - - - ko00000,ko02000 2.A.66.2.14 - - Polysacc_synt,Polysacc_synt_C k141_33413_1 1403313.AXBR01000026_gene5153 1.8e-83 266.0 COG0728@1|root,COG0728@2|Bacteria,1TPFI@1239|Firmicutes,4HBJ9@91061|Bacilli,1ZDMS@1386|Bacillus 91061|Bacilli S Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane murJ - - ko:K03980 - - - - ko00000,ko01011,ko02000 2.A.66.4 - - MVIN k141_4907_2 441769.ABFU01000060_gene653 7.49e-13 67.4 COG0557@1|root,COG0557@2|Bacteria,1TQ1G@1239|Firmicutes,4HBBH@91061|Bacilli,1ZBDP@1386|Bacillus 91061|Bacilli K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs rnr - - ko:K12573 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03016,ko03019 - - - OB_RNB,RNB,S1 k141_28738_1 42565.FP66_03275 8.46e-52 172.0 COG1638@1|root,COG1638@2|Bacteria,1MVHC@1224|Proteobacteria,1RSPY@1236|Gammaproteobacteria,1XN6F@135619|Oceanospirillales 135619|Oceanospirillales G transporter - - - - - - - - - - - - DctP k141_13266_2 393305.YE2642 3.36e-27 112.0 COG2977@1|root,COG2977@2|Bacteria,1MZK2@1224|Proteobacteria,1S968@1236|Gammaproteobacteria,41F50@629|Yersinia 1236|Gammaproteobacteria Q Phosphopantetheinyl transferase entD - - - - - - - - - - - ACPS k141_22751_1 1121938.AUDY01000009_gene2318 3.2e-42 153.0 COG3835@1|root,COG3835@2|Bacteria,1W7AX@1239|Firmicutes,4I2W0@91061|Bacilli,3NG62@45667|Halobacillus 91061|Bacilli KT Putative sugar diacid recognition - - - - - - - - - - - - Diacid_rec,HTH_30 k141_6208_1 401053.AciPR4_1853 6.34e-48 163.0 COG0767@1|root,COG0767@2|Bacteria,3Y43S@57723|Acidobacteria,2JI8E@204432|Acidobacteriia 204432|Acidobacteriia Q Belongs to the MlaE permease family - - - ko:K02066 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaE k141_14468_3 218284.CCDN010000008_gene4209 6.59e-47 154.0 2DMXQ@1|root,32UHX@2|Bacteria,1VD2A@1239|Firmicutes,4HKUA@91061|Bacilli,1ZJEN@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_26381_1 880070.Cycma_4594 2.07e-84 260.0 COG3385@1|root,COG3385@2|Bacteria,4NJC6@976|Bacteroidetes,47UVE@768503|Cytophagia 976|Bacteroidetes L PFAM Transposase DDE domain - - - - - - - - - - - - DDE_Tnp_1,DUF4372 k141_16812_1 290397.Adeh_3122 2.62e-53 176.0 COG0395@1|root,COG0395@2|Bacteria,1N4I0@1224|Proteobacteria,43AKX@68525|delta/epsilon subdivisions,2X612@28221|Deltaproteobacteria,2Z33J@29|Myxococcales 28221|Deltaproteobacteria P Binding-protein-dependent transport system inner membrane component - - - ko:K02026 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - BPD_transp_1 k141_19174_1 1453501.JELR01000001_gene1985 8.71e-79 246.0 COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,464ES@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the peptidase S1C family mucD GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Trypsin_2 k141_9665_1 1279017.AQYJ01000028_gene2451 1.27e-177 530.0 COG3468@1|root,COG3468@2|Bacteria,1R8WV@1224|Proteobacteria 1224|Proteobacteria MU outer membrane autotransporter barrel domain - - - ko:K19231 - - - - ko00000,ko02000 1.B.12 - - Autotransporter,Pertactin k141_9665_2 1279017.AQYJ01000028_gene2452 1.15e-87 267.0 COG3047@1|root,COG3047@2|Bacteria 2|Bacteria - - ompW - - ko:K07275 - - - - ko00000 - - - OmpW k141_9665_3 1042377.AFPJ01000012_gene1367 2.35e-96 283.0 COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,1S3VN@1236|Gammaproteobacteria,466US@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) purE - 5.4.99.18 ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07405 RC01947 ko00000,ko00001,ko00002,ko01000 - - - AIRC k141_9665_4 1042377.AFPJ01000012_gene1368 2.06e-220 613.0 COG0026@1|root,COG0026@2|Bacteria,1MU70@1224|Proteobacteria,1RQEI@1236|Gammaproteobacteria,46573@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) purK GO:0000166,GO:0003674,GO:0003824,GO:0004638,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0016874,GO:0016879,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034028,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.4.18 ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07404 RC01927 ko00000,ko00001,ko00002,ko01000 - - iECUMN_1333.ECUMN_0562,iYL1228.KPN_00477 ATP-grasp k141_9665_5 435908.IDSA_06975 4.83e-74 235.0 2DBB9@1|root,2Z86U@2|Bacteria,1RC32@1224|Proteobacteria,1S4RI@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_9665_6 1279017.AQYJ01000028_gene2458 7.71e-44 146.0 COG1320@1|root,COG1320@2|Bacteria,1RH17@1224|Proteobacteria,1S6Q4@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Na H antiporter - - - ko:K05571 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - PhaG_MnhG_YufB k141_9665_7 1042377.AFPJ01000053_gene1500 4.58e-35 123.0 COG2212@1|root,COG2212@2|Bacteria 2|Bacteria P antiporter activity mnhF - - ko:K05570 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - MrpF_PhaF k141_9665_8 1254432.SCE1572_16425 3.38e-30 114.0 COG1863@1|root,COG1863@2|Bacteria,1RB2I@1224|Proteobacteria,42TQZ@68525|delta/epsilon subdivisions,2WQD3@28221|Deltaproteobacteria,2YW1D@29|Myxococcales 28221|Deltaproteobacteria P Na+/H+ ion antiporter subunit - - - ko:K05562,ko:K05569 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - MNHE k141_9665_9 1279017.AQYJ01000028_gene2461 1.6e-258 721.0 COG0651@1|root,COG0651@2|Bacteria,1MURB@1224|Proteobacteria,1RQBG@1236|Gammaproteobacteria,465QH@72275|Alteromonadaceae 1236|Gammaproteobacteria CP COG0651 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit mnhD - - ko:K05568 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - Proton_antipo_M k141_9665_10 1279017.AQYJ01000028_gene2462 1.84e-51 166.0 COG1006@1|root,COG1006@2|Bacteria,1RH8H@1224|Proteobacteria,1SA5H@1236|Gammaproteobacteria,4682I@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1006 Multisubunit Na H antiporter, MnhC subunit phaC - 1.6.5.3 ko:K00340,ko:K05560,ko:K05567 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000,ko02000 2.A.63.1,2.A.63.2,3.D.1 - - Oxidored_q2 k141_9665_11 1294273.roselon_00570 9.68e-49 160.0 COG2111@1|root,COG2111@2|Bacteria,1REGG@1224|Proteobacteria,2UB7J@28211|Alphaproteobacteria 28211|Alphaproteobacteria P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali mnhB - - ko:K05566 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - MnhB k141_9665_12 1279017.AQYJ01000028_gene2464 1.58e-67 226.0 COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,1RNKN@1236|Gammaproteobacteria,463YS@72275|Alteromonadaceae 1236|Gammaproteobacteria CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit mnhA - - ko:K05565 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - DUF4040,MnhB,Proton_antipo_M,Proton_antipo_N k141_13287_1 265729.GS18_0221230 2.27e-65 210.0 COG2518@1|root,COG2518@2|Bacteria,1TXKM@1239|Firmicutes,4I6K8@91061|Bacilli,1ZF9E@1386|Bacillus 91061|Bacilli O Methyltransferase FkbM domain - - - - - - - - - - - - Methyltransf_21 k141_36992_1 1294265.JCM21738_1034 8.84e-107 310.0 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli,1ZAXK@1386|Bacillus 91061|Bacilli C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively - - - - - - - - - - - - Aldedh k141_6210_1 218284.CCDN010000001_gene610 1.14e-109 328.0 COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,4HBJM@91061|Bacilli,1ZAWN@1386|Bacillus 91061|Bacilli H Belongs to the folylpolyglutamate synthase family folC GO:0003674,GO:0003824,GO:0004326,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006761,GO:0006807,GO:0008150,GO:0008152,GO:0008841,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046452,GO:0046483,GO:0046900,GO:0046901,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 - - - Mur_ligase_C,Mur_ligase_M k141_7327_1 1122197.ATWI01000011_gene407 8.54e-59 194.0 COG2207@1|root,COG2207@2|Bacteria,1MX23@1224|Proteobacteria,1S1G1@1236|Gammaproteobacteria,46CNR@72275|Alteromonadaceae 1236|Gammaproteobacteria K Arabinose-binding domain of AraC transcription regulator, N-term - - - - - - - - - - - - Arabinose_bd,HTH_18 k141_21618_1 1384049.CD29_14930 2.84e-43 142.0 COG0346@1|root,COG0346@2|Bacteria,1V7WX@1239|Firmicutes,4HJ1B@91061|Bacilli,3IYHI@400634|Lysinibacillus 91061|Bacilli E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - Glyoxalase k141_21618_2 1536770.R50345_10435 1.29e-59 187.0 2EHWK@1|root,33BN6@2|Bacteria,1VMK0@1239|Firmicutes,4HSQV@91061|Bacilli,26ZZA@186822|Paenibacillaceae 91061|Bacilli - - - - - - - - - - - - - - - k141_264_1 246197.MXAN_3057 1.01e-14 77.8 COG0546@1|root,COG0546@2|Bacteria,1P7U4@1224|Proteobacteria,432VF@68525|delta/epsilon subdivisions,2WYF8@28221|Deltaproteobacteria,2YVV8@29|Myxococcales 28221|Deltaproteobacteria S HAD-hyrolase-like gph1 - - - - - - - - - - - HAD,Hydrolase_like k141_26384_1 218284.CCDN010000006_gene3653 1.37e-77 243.0 COG3595@1|root,COG3595@2|Bacteria,1TS90@1239|Firmicutes,4HDI6@91061|Bacilli,1ZC95@1386|Bacillus 91061|Bacilli S Putative adhesin yvlB - - - - - - - - - - - DUF4097 k141_8535_2 218284.CCDN010000001_gene1259 1.49e-78 242.0 COG1277@1|root,COG1277@2|Bacteria,1UYUR@1239|Firmicutes,4HEAP@91061|Bacilli,1ZCZZ@1386|Bacillus 91061|Bacilli S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component yxlG - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_2,ABC2_membrane_5 k141_32221_1 1042377.AFPJ01000017_gene16 4.67e-47 156.0 COG3453@1|root,COG3453@2|Bacteria,1N9AF@1224|Proteobacteria,1T4JK@1236|Gammaproteobacteria,46D8N@72275|Alteromonadaceae 1236|Gammaproteobacteria S Putative phosphatase (DUF442) - - 1.8.5.4 ko:K17218 ko00920,map00920 - R10152 RC03155 ko00000,ko00001,ko01000 - - - DUF442 k141_32221_2 1453501.JELR01000001_gene2598 7.06e-252 708.0 COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,1SYC8@1236|Gammaproteobacteria,4647C@72275|Alteromonadaceae 1236|Gammaproteobacteria P Sulfate permease family sulP - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - STAS,Sulfate_transp k141_32221_3 604331.AUHY01000016_gene1412 1.42e-13 71.6 COG2021@1|root,COG2021@2|Bacteria,1WIIY@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus E TAP-like protein - - 3.1.1.24 ko:K01055 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00568 R02991 RC00825 ko00000,ko00001,ko00002,ko01000 - - - Abhydrolase_1,Abhydrolase_6 k141_16813_1 218284.CCDN010000009_gene4277 2.26e-147 431.0 COG0449@1|root,COG0449@2|Bacteria,1TPGU@1239|Firmicutes,4H9R4@91061|Bacilli,1ZBI5@1386|Bacillus 91061|Bacilli M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source glmS GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 - R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 - - iSB619.SA_RS11245,iYO844.BSU01780 GATase_6,SIS k141_14469_1 1132442.KB889752_gene3092 0.000489 45.1 COG0366@1|root,COG0366@2|Bacteria,1UJZV@1239|Firmicutes,4ITG4@91061|Bacilli,1ZG7U@1386|Bacillus 91061|Bacilli G S-layer homology domain - - - - - - - - - - - - SLH k141_14469_2 1273538.G159_16215 9.11e-09 58.2 2C6U3@1|root,32T26@2|Bacteria,1VCHY@1239|Firmicutes,4HMF4@91061|Bacilli,26FWE@186818|Planococcaceae 91061|Bacilli - - - - - - - - - - - - - - - k141_8791_1 102125.Xen7305DRAFT_00024850 8.84e-05 47.4 COG1874@1|root,COG1874@2|Bacteria,1GH6K@1117|Cyanobacteria,3VNCP@52604|Pleurocapsales 1117|Cyanobacteria G Beta-galactosidase - - - - - - - - - - - - - k141_35978_1 321955.AAGP01000003_gene2891 0.000673 47.8 COG0624@1|root,COG0624@2|Bacteria,2GK09@201174|Actinobacteria,4F8FM@85019|Brevibacteriaceae 201174|Actinobacteria E Peptidase family M28 dapE - 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20,Peptidase_M28 k141_13614_1 218284.CCDN010000001_gene1674 2.28e-101 301.0 COG0662@1|root,COG0662@2|Bacteria,1V3H4@1239|Firmicutes,4HH1K@91061|Bacilli,1ZFFQ@1386|Bacillus 91061|Bacilli G Cupin domain - - - - - - - - - - - - Cupin_2 k141_25404_1 218284.CCDN010000002_gene2566 2.93e-165 464.0 2C0DW@1|root,2Z7ZI@2|Bacteria,1UDVF@1239|Firmicutes,4HBY7@91061|Bacilli,1ZCS2@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_25404_2 218284.CCDN010000002_gene2567 2.87e-49 160.0 2BF3X@1|root,328W3@2|Bacteria,1V673@1239|Firmicutes,4HNG9@91061|Bacilli,1ZG28@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_26757_2 1395571.TMS3_0115850 1.48e-115 340.0 COG0454@1|root,COG0454@2|Bacteria,1MVVG@1224|Proteobacteria,1RQ5J@1236|Gammaproteobacteria 1236|Gammaproteobacteria K acetyltransferase - - - - - - - - - - - - Acetyltransf_1 k141_18302_2 218284.CCDN010000004_gene3025 4.36e-133 378.0 COG2208@1|root,COG2208@2|Bacteria,1V0BN@1239|Firmicutes,4HECS@91061|Bacilli,1ZEVQ@1386|Bacillus 91061|Bacilli KT Sigma factor PP2C-like phosphatases rsbX GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0050896 3.1.3.3 ko:K05518 - - - - ko00000,ko01000,ko03021 - - - PP2C_2,SpoIIE k141_5158_1 768066.HELO_3719 4.33e-65 216.0 COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,1RPAV@1236|Gammaproteobacteria,1XHFN@135619|Oceanospirillales 135619|Oceanospirillales L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA ligA - 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - - BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5 k141_5158_2 42565.FP66_10980 1.31e-38 140.0 COG3115@1|root,COG3115@2|Bacteria,1MVHR@1224|Proteobacteria,1RMDB@1236|Gammaproteobacteria,1XKA8@135619|Oceanospirillales 135619|Oceanospirillales D Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins zipA - - ko:K03528 - - - - ko00000,ko03036 - - - ZipA_C k141_9951_1 1042377.AFPJ01000045_gene2578 4.83e-77 254.0 COG4223@1|root,COG4223@2|Bacteria,1N10X@1224|Proteobacteria,1RYCQ@1236|Gammaproteobacteria,46D2D@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF1631) - - - - - - - - - - - - DUF1631 k141_19428_2 1453501.JELR01000001_gene2969 1.18e-24 99.8 COG4535@1|root,COG4535@2|Bacteria,1QTU8@1224|Proteobacteria,1RMKX@1236|Gammaproteobacteria,4658M@72275|Alteromonadaceae 1236|Gammaproteobacteria P Mg2 and Co2 transporter CorC corC GO:0001897,GO:0001906,GO:0001907,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009405,GO:0009987,GO:0016020,GO:0019835,GO:0019836,GO:0031640,GO:0035821,GO:0044003,GO:0044004,GO:0044179,GO:0044364,GO:0044403,GO:0044419,GO:0044464,GO:0044764,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0071944 - ko:K06189 - - - - ko00000,ko02000 9.A.40.1.2 - - CBS,CorC_HlyC k141_31293_1 218284.CCDN010000008_gene4212 2.88e-180 503.0 COG4848@1|root,COG4848@2|Bacteria,1TTBU@1239|Firmicutes,4HAD1@91061|Bacilli,1ZBQ7@1386|Bacillus 91061|Bacilli S Belongs to the UPF0354 family ytpQ - - - - - - - - - - - DUF1444 k141_13615_1 42565.FP66_10135 5.15e-164 462.0 COG0010@1|root,COG0010@2|Bacteria,1MVFH@1224|Proteobacteria,1RMH5@1236|Gammaproteobacteria,1XHZF@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the arginase family - - 3.5.3.11,3.5.3.7 ko:K01480,ko:K12255 ko00330,ko01100,map00330,map01100 M00133 R01157,R01990 RC00024,RC00329 ko00000,ko00001,ko00002,ko01000 - - - Arginase k141_11118_1 1121938.AUDY01000010_gene2936 1.98e-101 309.0 COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HB3V@91061|Bacilli,3ND2G@45667|Halobacillus 91061|Bacilli IQ AMP-binding enzyme C-terminal domain - - - ko:K00666 - - - - ko00000,ko01000,ko01004 - - - AMP-binding,AMP-binding_C k141_26758_1 218284.CCDN010000002_gene2055 2.99e-130 385.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4H9SC@91061|Bacilli,1ZBEE@1386|Bacillus 91061|Bacilli V ABC transporter malQ - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran k141_20562_1 218284.CCDN010000002_gene2857 1.67e-74 229.0 COG5482@1|root,COG5482@2|Bacteria,1V3FI@1239|Firmicutes,4HI6C@91061|Bacilli,1ZDPW@1386|Bacillus 91061|Bacilli S Putative PD-(D/E)XK phosphodiesterase (DUF2161) - - - - - - - - - - - - DUF2161 k141_20562_2 1118054.CAGW01000062_gene2345 2.83e-31 115.0 COG1595@1|root,COG1595@2|Bacteria,1VB3P@1239|Firmicutes,4HJ20@91061|Bacilli,26Z9I@186822|Paenibacillaceae 91061|Bacilli K Sigma-70, region 4 - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_33730_1 666686.B1NLA3E_20395 2.51e-147 425.0 COG2704@1|root,COG2704@2|Bacteria,1TR0A@1239|Firmicutes,4HE73@91061|Bacilli,1ZFEA@1386|Bacillus 91061|Bacilli S anaerobic c4-dicarboxylate dcuB - - ko:K07791,ko:K07792 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.13.1 - - DcuA_DcuB k141_25406_1 344747.PM8797T_28859 4.01e-18 79.7 COG0636@1|root,COG0636@2|Bacteria,2J0QD@203682|Planctomycetes 203682|Planctomycetes P F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpE - - ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_C k141_19429_1 218284.CCDN010000008_gene4129 1.45e-91 287.0 COG4872@1|root,COG4929@1|root,COG4872@2|Bacteria,COG4929@2|Bacteria,1UZI7@1239|Firmicutes,4HEJJ@91061|Bacilli,1ZEAE@1386|Bacillus 91061|Bacilli S Predicted membrane protein (DUF2157) - - - - - - - - - - - - DUF2157,DUF4401,GDYXXLXY k141_556_2 908337.HMPREF9257_1764 0.000576 46.2 COG2267@1|root,COG2267@2|Bacteria,1TSC4@1239|Firmicutes,4HBYX@91061|Bacilli 91061|Bacilli I hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - - - - - - - - - - Abhydrolase_1,Hydrolase_4 k141_34882_1 1294265.JCM21738_607 1.03e-37 132.0 COG0029@1|root,COG0029@2|Bacteria,1UHSP@1239|Firmicutes,4H9ZZ@91061|Bacilli,1ZBIE@1386|Bacillus 91061|Bacilli H Catalyzes the oxidation of L-aspartate to iminoaspartate nadB - 1.4.3.16 ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 M00115 R00357,R00481 RC00006,RC02566 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C k141_37209_1 261726.A2I2Y1_9CAUD 2.36e-39 150.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QHYN@10662|Myoviridae 10662|Myoviridae S amidase activity - - - - - - - - - - - - - k141_1557_1 558169.AGAV01000015_gene408 1.58e-110 330.0 COG1114@1|root,COG1114@2|Bacteria,1TQIS@1239|Firmicutes,4HAKA@91061|Bacilli 91061|Bacilli E Component of the transport system for branched-chain amino acids - - - ko:K03311 - - - - ko00000 2.A.26 - - Branch_AA_trans k141_26781_1 218284.CCDN010000007_gene3966 1.21e-21 91.7 COG1172@1|root,COG1172@2|Bacteria,1TP72@1239|Firmicutes,4HBU9@91061|Bacilli,1ZQAD@1386|Bacillus 91061|Bacilli G Belongs to the binding-protein-dependent transport system permease family rbsC3 - - ko:K02057 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - BPD_transp_2 k141_26781_2 218284.CCDN010000007_gene3967 2.13e-43 146.0 COG4821@1|root,COG4821@2|Bacteria,1VJUP@1239|Firmicutes,4HP1J@91061|Bacilli,1ZH7S@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF2529) ywjG - - - - - - - - - - - DUF2529 k141_7508_1 1279017.AQYJ01000023_gene3172 5.09e-63 196.0 COG0838@1|root,COG0838@2|Bacteria,1RGUT@1224|Proteobacteria,1S644@1236|Gammaproteobacteria,46AXU@72275|Alteromonadaceae 1236|Gammaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoA - 1.6.5.3 ko:K00330 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q4 k141_7508_2 1279017.AQYJ01000023_gene3171 6.33e-49 161.0 COG0377@1|root,COG0377@2|Bacteria,1MUI2@1224|Proteobacteria,1RP4R@1236|Gammaproteobacteria,469EA@72275|Alteromonadaceae 1236|Gammaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoB - 1.6.5.3 ko:K00331 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q6 k141_34884_1 218284.CCDN010000001_gene503 1.41e-53 173.0 COG1595@1|root,COG1595@2|Bacteria,1V5U1@1239|Firmicutes,4IPXD@91061|Bacilli,1ZRE6@1386|Bacillus 91061|Bacilli K Sigma-70, region 4 - - - - - - - - - - - - Sigma70_r2,Sigma70_r4_2 k141_13623_1 1116375.VEJY3_16746 3.26e-293 803.0 COG1488@1|root,COG1488@2|Bacteria,1MV8U@1224|Proteobacteria,1RQWS@1236|Gammaproteobacteria,1XSPB@135623|Vibrionales 135623|Vibrionales F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP pncB GO:0003674,GO:0003824,GO:0004516,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009987,GO:0016874,GO:0016879,GO:0019362,GO:0019637,GO:0019674,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901360,GO:1901564 6.3.4.21 ko:K00763 ko00760,ko01100,map00760,map01100 - R01724 RC00033 ko00000,ko00001,ko01000 - - - NAPRTase k141_13623_3 223926.28808476 1.1e-81 241.0 2AMKZ@1|root,31CGY@2|Bacteria,1R3MH@1224|Proteobacteria,1T69M@1236|Gammaproteobacteria,1XXDZ@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_13623_4 1116375.VEJY3_16756 1.28e-78 238.0 COG3134@1|root,COG3134@2|Bacteria,1MVWD@1224|Proteobacteria,1RQR9@1236|Gammaproteobacteria,1XV9N@135623|Vibrionales 135623|Vibrionales S Glycine zipper 2TM domain - - - - - - - - - - - - Rick_17kDa_Anti k141_13623_5 1116375.VEJY3_16761 7.13e-183 512.0 COG0697@1|root,COG0697@2|Bacteria,1R9B0@1224|Proteobacteria,1RZ6Q@1236|Gammaproteobacteria,1Y2CK@135623|Vibrionales 135623|Vibrionales EG EamA-like transporter family - - - - - - - - - - - - EamA k141_13623_6 1116375.VEJY3_16766 1.91e-202 561.0 COG0583@1|root,COG0583@2|Bacteria,1QN6R@1224|Proteobacteria,1RSKY@1236|Gammaproteobacteria,1XVKA@135623|Vibrionales 135623|Vibrionales K Bacterial regulatory helix-turn-helix protein, lysR family - - - - - - - - - - - - HTH_1,LysR_substrate k141_13623_7 1116375.VEJY3_16771 1.27e-80 243.0 COG3015@1|root,COG3015@2|Bacteria,1N97X@1224|Proteobacteria,1SEMN@1236|Gammaproteobacteria,1XXAR@135623|Vibrionales 135623|Vibrionales MP lipoprotein NlpE involved in copper resistance - - - - - - - - - - - - NlpE k141_13623_8 1116375.VEJY3_16791 1.24e-37 126.0 2AWP4@1|root,31NK1@2|Bacteria,1QKAP@1224|Proteobacteria,1TIE7@1236|Gammaproteobacteria,1XYYW@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_13623_9 1116375.VEJY3_16796 0.0 1257.0 COG0480@1|root,COG0480@2|Bacteria,1MVVY@1224|Proteobacteria,1RYCE@1236|Gammaproteobacteria,1XU1K@135623|Vibrionales 135623|Vibrionales J COG0480 Translation elongation factors (GTPases) - - - ko:K02355 - - - - ko00000,ko03012,ko03029 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU k141_13623_10 1116375.VEJY3_16806 5.55e-214 598.0 COG0477@1|root,COG2814@2|Bacteria,1NCX2@1224|Proteobacteria,1SKAQ@1236|Gammaproteobacteria,1Y2CN@135623|Vibrionales 135623|Vibrionales EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 k141_13623_11 1116375.VEJY3_16811 7.4e-96 279.0 COG0789@1|root,COG0789@2|Bacteria,1RH2U@1224|Proteobacteria,1S6M0@1236|Gammaproteobacteria,1XVN9@135623|Vibrionales 135623|Vibrionales K transcriptional regulators soxR - - ko:K13639 - - - - ko00000,ko03000 - - - MerR,MerR-DNA-bind,MerR_1 k141_13623_12 1116375.VEJY3_16816 1.88e-75 227.0 COG4711@1|root,COG4711@2|Bacteria,1RJII@1224|Proteobacteria,1S65R@1236|Gammaproteobacteria,1XXE7@135623|Vibrionales 135623|Vibrionales S Putative integral membrane protein (DUF2391) - - - - - - - - - - - - DUF2391 k141_13623_13 1116375.VEJY3_16821 9.33e-188 523.0 COG0457@1|root,COG0457@2|Bacteria,1PNM7@1224|Proteobacteria,1RXYT@1236|Gammaproteobacteria,1XVBC@135623|Vibrionales 135623|Vibrionales S COG0457 FOG TPR repeat - - - - - - - - - - - - Alkyl_sulf_dimr,TPR_8 k141_13623_14 1116375.VEJY3_16826 1.96e-52 167.0 COG4405@1|root,COG4405@2|Bacteria,1N2T4@1224|Proteobacteria,1S2GH@1236|Gammaproteobacteria,1XX11@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria - - - - - - - - - - - - ASCH k141_13623_15 1116375.VEJY3_16831 1.85e-308 847.0 COG1502@1|root,COG1502@2|Bacteria,1MUDJ@1224|Proteobacteria,1RMIF@1236|Gammaproteobacteria,1XT1S@135623|Vibrionales 135623|Vibrionales I COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes - - - ko:K06132 ko00564,ko01100,map00564,map01100 - R11062 RC00017 ko00000,ko00001,ko01000 - - - PLDc_2 k141_13623_16 1116375.VEJY3_16836 8.39e-245 676.0 COG0845@1|root,COG0845@2|Bacteria,1N0BG@1224|Proteobacteria,1RMXD@1236|Gammaproteobacteria,1XUQT@135623|Vibrionales 135623|Vibrionales M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - - - - - - - - - - Biotin_lipoyl_2,HlyD_3 k141_13623_17 1116375.VEJY3_16841 0.0 1936.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1XTIP@135623|Vibrionales 135623|Vibrionales V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran k141_13623_18 223926.28808511 2.82e-38 129.0 2AWIB@1|root,31NEW@2|Bacteria,1QK5Z@1224|Proteobacteria,1TI96@1236|Gammaproteobacteria,1XYPA@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_15852_1 1294265.JCM21738_1364 4.48e-142 406.0 COG0492@1|root,COG0492@2|Bacteria,1TRPN@1239|Firmicutes,4H9V7@91061|Bacilli,1ZCEZ@1386|Bacillus 91061|Bacilli C reductase yumC - 1.18.1.2,1.19.1.1 ko:K21567 - - - - ko00000,ko01000 - - iYO844.BSU32110 Pyr_redox_2 k141_32408_1 1121090.KB894688_gene1700 1.17e-105 316.0 COG2873@1|root,COG2873@2|Bacteria,1VYCY@1239|Firmicutes,4H9X5@91061|Bacilli,1ZS2F@1386|Bacillus 91061|Bacilli E O-acetylhomoserine metY - 2.5.1.49 ko:K01740 ko00270,ko01100,map00270,map01100 - R01287,R04859 RC00020,RC02821,RC02848 ko00000,ko00001,ko01000 - - - Cys_Met_Meta_PP k141_21830_2 35841.BT1A1_1437 7.77e-24 91.7 COG4896@1|root,COG4896@2|Bacteria,1VFMW@1239|Firmicutes,4HNPM@91061|Bacilli,1ZIXV@1386|Bacillus 91061|Bacilli S protein conserved in bacteria ylaI - - - - - - - - - - - DUF2197 k141_19448_1 1294265.JCM21738_2731 7.98e-27 105.0 COG0109@1|root,COG0109@2|Bacteria,1TPS1@1239|Firmicutes,4HBJT@91061|Bacilli,1ZCJT@1386|Bacillus 91061|Bacilli O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group ctaB GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 M00154 R07411 RC01786 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 - - iSB619.SA_RS05465 UbiA k141_19448_2 1294265.JCM21738_2732 3.36e-147 421.0 COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,1TRC3@1239|Firmicutes,4HADQ@91061|Bacilli,1ZAP8@1386|Bacillus 91061|Bacilli C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) ctaC GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.9.3.1 ko:K02275 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.4,3.D.4.6 - - COX2,COX2_TM,Cytochrom_C,Cytochrome_CBB3 k141_17057_2 506534.Rhein_1960 3.02e-44 150.0 COG1670@1|root,COG1670@2|Bacteria,1RCX2@1224|Proteobacteria,1S42B@1236|Gammaproteobacteria,1X0T8@135613|Chromatiales 135613|Chromatiales J Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_3 k141_17057_3 1279017.AQYJ01000019_gene1480 0.0 1776.0 COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,1RMS9@1236|Gammaproteobacteria,464B1@72275|Alteromonadaceae 1236|Gammaproteobacteria L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate uvrA GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009380,GO:0009381,GO:0009628,GO:0009987,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran k141_17057_4 1453501.JELR01000005_gene1752 3.02e-169 485.0 COG0836@1|root,COG0836@2|Bacteria,1MV39@1224|Proteobacteria,1RNQI@1236|Gammaproteobacteria,4644C@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the mannose-6-phosphate isomerase type 2 family algA - 2.7.7.13,5.3.1.8 ko:K00971,ko:K16011 ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025 M00114,M00361,M00362 R00885,R01819 RC00002,RC00376 ko00000,ko00001,ko00002,ko01000 - - - MannoseP_isomer,NTP_transferase k141_12462_2 325452.fgenesh_scip_prom.46568.93 8.39e-29 119.0 COG0488@1|root,COG1957@1|root,KOG0927@2759|Eukaryota,KOG2938@2759|Eukaryota,3Q7CN@4776|Peronosporales 4776|Peronosporales F Inosine-uridine preferring nucleoside hydrolase - - - - - - - - - - - - IU_nuc_hydro k141_33748_1 1207055.C100_01630 2.57e-191 537.0 COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,2TQTP@28211|Alphaproteobacteria,2K2SD@204457|Sphingomonadales 204457|Sphingomonadales L Transposase - - - ko:K07486 - - - - ko00000 - - - DEDD_Tnp_IS110,Transposase_20 k141_1558_1 574376.BAMA_16580 1.94e-147 416.0 COG0775@1|root,COG0775@2|Bacteria,1UPMC@1239|Firmicutes,4HAWJ@91061|Bacilli,1ZE9V@1386|Bacillus 91061|Bacilli F Phosphorylase superfamily - - 3.2.2.9 ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 M00034,M00609 R00194,R01401 RC00063,RC00318 ko00000,ko00001,ko00002,ko01000 - - - PNP_UDP_1 k141_13624_1 935836.JAEL01000079_gene120 3.96e-40 137.0 COG1863@1|root,COG1863@2|Bacteria,1V52M@1239|Firmicutes,4HI4G@91061|Bacilli,1ZGAK@1386|Bacillus 91061|Bacilli P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali mrpE - - ko:K05569 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - MNHE k141_24150_1 1042377.AFPJ01000037_gene2957 8.66e-54 170.0 COG2827@1|root,COG2827@2|Bacteria,1N6PA@1224|Proteobacteria,1SCBH@1236|Gammaproteobacteria,468FM@72275|Alteromonadaceae 1236|Gammaproteobacteria L GIY-YIG catalytic domain yhbQ GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - ko:K07461 - - - - ko00000 - - - GIY-YIG k141_24150_2 1042375.AFPL01000016_gene27 1.56e-67 211.0 COG1028@1|root,COG1028@2|Bacteria,1RHYX@1224|Proteobacteria,1S0GN@1236|Gammaproteobacteria,46D27@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) csgA - - - - - - - - - - - adh_short k141_14649_2 1033734.CAET01000018_gene773 5.03e-27 108.0 COG1893@1|root,COG1893@2|Bacteria,1V1NJ@1239|Firmicutes,4HFWT@91061|Bacilli,1ZFJY@1386|Bacillus 91061|Bacilli H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid panE GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008677,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU15110 ApbA,ApbA_C k141_31298_1 1219076.N646_2289 1.23e-106 311.0 COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,1RPRN@1236|Gammaproteobacteria,1XTQ1@135623|Vibrionales 135623|Vibrionales U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides tatC - - ko:K03118 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - TatC k141_31298_2 1116375.VEJY3_00455 4.22e-74 223.0 COG1826@1|root,COG1826@2|Bacteria,1N73F@1224|Proteobacteria,1SD9K@1236|Gammaproteobacteria,1XXXV@135623|Vibrionales 135623|Vibrionales U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation tatB - - ko:K03117 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - MttA_Hcf106 k141_31298_3 1116375.VEJY3_00450 1.06e-39 133.0 COG1826@1|root,COG1826@2|Bacteria,1N6S4@1224|Proteobacteria,1SCC7@1236|Gammaproteobacteria,1XYC6@135623|Vibrionales 135623|Vibrionales U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system tatA GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - ko:K03116 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - MttA_Hcf106 k141_31298_4 1116375.VEJY3_00445 0.0 1082.0 COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,1RNQM@1236|Gammaproteobacteria,1XSB2@135623|Vibrionales 135623|Vibrionales H Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis ubiB GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 - ko:K03688 - - - - ko00000 - - - ABC1 k141_31298_5 1116375.VEJY3_00440 3.85e-139 394.0 COG3165@1|root,COG3165@2|Bacteria,1R1CM@1224|Proteobacteria,1S745@1236|Gammaproteobacteria,1XUNJ@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria - - - ko:K03690 - - - - ko00000 - - - SCP2 k141_31298_6 223926.28805077 2.5e-185 515.0 COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,1RMAU@1236|Gammaproteobacteria,1XSR2@135623|Vibrionales 135623|Vibrionales H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) ubiE GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.1.1.163,2.1.1.201 ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116,M00117 R04990,R04993,R06859,R08774,R09736 RC00003,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000 - - - Ubie_methyltran k141_31298_7 1116375.VEJY3_00430 4.61e-304 837.0 COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,1RMB8@1236|Gammaproteobacteria,1XV2P@135623|Vibrionales 135623|Vibrionales S dna recombination protein rmuc rmuC - - ko:K09760 - - - - ko00000 - - - RmuC k141_30039_1 1294265.JCM21738_3488 4.98e-157 447.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,1ZBYG@1386|Bacillus 91061|Bacilli I Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation mmgA GO:0003674,GO:0003824,GO:0003988,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - iYO844.BSU24170 Thiolase_C,Thiolase_N k141_37210_1 1294265.JCM21738_2771 1.04e-75 235.0 2AZZM@1|root,31S9P@2|Bacteria,1V6WH@1239|Firmicutes,4HMZM@91061|Bacilli,1ZDWA@1386|Bacillus 91061|Bacilli S YtxC-like family ytxC - - - - - - - - - - - YtxC k141_12463_1 1294265.JCM21738_212 1.79e-69 216.0 COG2897@1|root,COG2897@2|Bacteria,1TRYA@1239|Firmicutes,4HAQA@91061|Bacilli,1ZANF@1386|Bacillus 91061|Bacilli P sulfurtransferase sseA - 2.8.1.1,2.8.1.2 ko:K01011 ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122 - R01931,R03105,R03106 RC00214 ko00000,ko00001,ko01000 - - - Rhodanese k141_12463_2 1294265.JCM21738_213 2.71e-63 201.0 COG0258@1|root,COG0258@2|Bacteria,1TQ05@1239|Firmicutes,4H9UW@91061|Bacilli,1ZB2Z@1386|Bacillus 91061|Bacilli L 5'3' exonuclease ypcP - - - - - - - - - - - 5_3_exonuc,5_3_exonuc_N k141_20584_1 211165.AJLN01000084_gene1744 1.33e-23 99.8 2DDZV@1|root,32U2A@2|Bacteria,1G7V6@1117|Cyanobacteria 1117|Cyanobacteria - - - - - - - - - - - - - - - k141_20584_2 379731.PST_2430 9.48e-12 60.8 2EGMT@1|root,33ADY@2|Bacteria,1NH3I@1224|Proteobacteria,1SGAI@1236|Gammaproteobacteria,1Z3CG@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria S Phospholipase_D-nuclease N-terminal IV01_13290 - - - - - - - - - - - PLDc_N k141_11147_1 1279017.AQYJ01000018_gene825 0.0 1061.0 COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,1RNM8@1236|Gammaproteobacteria,4656A@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family fadH - 1.3.1.34 ko:K00219 - - - - ko00000,ko01000 - - - Oxidored_FMN,Pyr_redox_2 k141_34885_1 218284.CCDN010000002_gene2255 1.6e-172 499.0 COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,4H9SP@91061|Bacilli,1ZAPS@1386|Bacillus 91061|Bacilli P COG2217 Cation transport ATPase zosA - 3.6.3.3,3.6.3.5 ko:K01534 - - - - ko00000,ko01000 3.A.3.6 - - E1-E2_ATPase,Hydrolase k141_34885_2 1382305.AZUC01000046_gene541 1.34e-31 115.0 COG2318@1|root,COG2318@2|Bacteria,1V415@1239|Firmicutes,4HH2D@91061|Bacilli,26FHI@186818|Planococcaceae 91061|Bacilli S Protein of unknown function (DUF1572) - - - - - - - - - - - - DUF1572 k141_14650_1 1121091.AUMP01000043_gene3894 4.12e-37 131.0 COG3601@1|root,COG3601@2|Bacteria,1V4BW@1239|Firmicutes,4HHFT@91061|Bacilli 91061|Bacilli U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins ribU GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656 - - - - - - - - - - ECF_trnsprt k141_7509_2 1279017.AQYJ01000028_gene2052 5.59e-157 445.0 COG1218@1|root,COG1218@2|Bacteria,1N0GY@1224|Proteobacteria,1RP5A@1236|Gammaproteobacteria,4642N@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1218 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase cysQ - 3.1.3.7 ko:K01082 ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130 - R00188,R00508 RC00078 ko00000,ko00001,ko01000,ko03016 - - - Inositol_P k141_11149_1 95619.PM1_0205685 4.11e-40 147.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria 1236|Gammaproteobacteria T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains pilR - - ko:K02481,ko:K02667 ko02020,map02020 M00501 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - HTH_8,Response_reg,Sigma54_activat k141_1561_1 406124.ACPC01000020_gene3806 1.58e-12 63.5 COG1396@1|root,COG1396@2|Bacteria,1VAXE@1239|Firmicutes,4HKHB@91061|Bacilli,1ZHZH@1386|Bacillus 91061|Bacilli K transcriptional sinR GO:0008150,GO:0009892,GO:0010468,GO:0010605,GO:0010629,GO:0019222,GO:0048519,GO:0050789,GO:0060255,GO:0065007 - ko:K19449 - - - - ko00000,ko03000 - - - HTH_3,SinI k141_28939_1 218284.CCDN010000004_gene3024 1.47e-262 739.0 COG2183@1|root,COG2183@2|Bacteria,1TPFE@1239|Firmicutes,4HAGY@91061|Bacilli,1ZC3T@1386|Bacillus 91061|Bacilli K COG2183 Transcriptional accessory protein tex - - ko:K06959 - - - - ko00000 - - - HHH_3,S1,Tex_N,Tex_YqgF k141_25466_6 1280001.BAOA01000014_gene996 5.46e-134 398.0 2AX79@1|root,31P5Z@2|Bacteria,1QKV7@1224|Proteobacteria,1TJ0H@1236|Gammaproteobacteria,1Y07I@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_25466_7 981384.AEYW01000012_gene1050 2.47e-25 103.0 COG1638@1|root,COG1638@2|Bacteria,1R5WY@1224|Proteobacteria,2TVHA@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Bacterial extracellular solute-binding protein, family 7 - - - - - - - - - - - - DctP k141_2791_1 218284.CCDN010000007_gene3955 2.32e-124 363.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,1ZBYG@1386|Bacillus 91061|Bacilli I Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation mmgA GO:0003674,GO:0003824,GO:0003988,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - iYO844.BSU24170 Thiolase_C,Thiolase_N k141_35161_1 586416.GZ22_13025 8.13e-77 236.0 COG2323@1|root,COG2323@2|Bacteria,1V1AI@1239|Firmicutes,4HDBF@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF421) - - - - - - - - - - - - DUF421 k141_17254_1 42565.FP66_01310 4.19e-212 589.0 COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,1RMUI@1236|Gammaproteobacteria,1XI0U@135619|Oceanospirillales 135619|Oceanospirillales J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs rlmN - 2.1.1.192 ko:K06941 - - - - ko00000,ko01000,ko03009 - - - Radical_SAM k141_33951_1 218284.CCDN010000008_gene4166 2e-84 253.0 COG1268@1|root,COG1268@2|Bacteria,1VAY6@1239|Firmicutes,4HHJM@91061|Bacilli,1ZEP6@1386|Bacillus 91061|Bacilli S BioY family bioY2 - - ko:K03523 ko02010,map02010 M00581,M00582 - - ko00000,ko00001,ko00002,ko02000 2.A.88.1,2.A.88.2 - - BioY k141_33951_2 218284.CCDN010000008_gene4167 1e-147 420.0 COG3393@1|root,COG3393@2|Bacteria,1UFJG@1239|Firmicutes,4HGNR@91061|Bacilli,1ZEBH@1386|Bacillus 91061|Bacilli S GNAT acetyltransferase - - - ko:K06976 - - - - ko00000 - - - Acetyltransf_10,Acetyltransf_9,GNAT_acetyltran k141_32597_1 1279017.AQYJ01000024_gene1105 1.07e-38 143.0 COG0389@1|root,COG0389@2|Bacteria,1MU5X@1224|Proteobacteria,1S28B@1236|Gammaproteobacteria,465IA@72275|Alteromonadaceae 1236|Gammaproteobacteria L Nucleotidyltransferase DNA polymerase involved in DNA repair imuB - - ko:K14161 - - - - ko00000,ko03400 - - - IMS k141_35162_1 1123242.JH636434_gene5396 1.24e-93 306.0 COG0060@1|root,COG0060@2|Bacteria,2IWX2@203682|Planctomycetes 203682|Planctomycetes J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1,zf-FPG_IleRS k141_9024_1 1274524.BSONL12_04029 2.45e-43 150.0 COG0180@1|root,COG0180@2|Bacteria,1TPY7@1239|Firmicutes,4HA1K@91061|Bacilli,1ZCUY@1386|Bacillus 91061|Bacilli J Tryptophanyl-tRNA synthetase trpS - 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1b k141_9024_2 218284.CCDN010000005_gene3277 2.75e-135 386.0 28IPR@1|root,2Z8PJ@2|Bacteria,1TPYR@1239|Firmicutes,4HBI7@91061|Bacilli,1ZAX0@1386|Bacillus 91061|Bacilli S Belongs to the UPF0736 family yjbA - - - - - - - - - - - DUF3603 k141_24402_1 1294265.JCM21738_284 7.12e-179 503.0 COG0758@1|root,COG0758@2|Bacteria,1TPP7@1239|Firmicutes,4HGWM@91061|Bacilli,1ZBZ3@1386|Bacillus 91061|Bacilli LU Rossmann fold nucleotide-binding protein involved in DNA uptake dprA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0007154,GO:0008150,GO:0009292,GO:0009294,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0044424,GO:0044464,GO:0044764,GO:0050896,GO:0051704,GO:0051716,GO:0071496 - ko:K04096 - - - - ko00000 - - - DNA_processg_A k141_29108_1 1453501.JELR01000001_gene2001 7.79e-92 276.0 COG2084@1|root,COG2084@2|Bacteria,1MUGU@1224|Proteobacteria,1RQ2D@1236|Gammaproteobacteria,464XV@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases garR - 1.1.1.31,1.1.1.60 ko:K00020,ko:K00042 ko00280,ko00630,ko01100,map00280,map00630,map01100 - R01745,R01747,R05066 RC00099 ko00000,ko00001,ko01000 - - - NAD_binding_11,NAD_binding_2 k141_27023_1 666681.M301_1817 4.44e-60 200.0 COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,2VIE4@28216|Betaproteobacteria 28216|Betaproteobacteria L PFAM transposase, IS4 family protein - - - ko:K07487 - - - - ko00000 - - - DDE_Tnp_1,DDE_Tnp_1_6,DUF772 k141_17255_1 1042377.AFPJ01000037_gene3026 9.09e-142 405.0 COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,1RQ59@1236|Gammaproteobacteria,465TZ@72275|Alteromonadaceae 1236|Gammaproteobacteria E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline argF - 2.1.3.3,2.1.3.6,2.1.3.9 ko:K00611,ko:K09065,ko:K13252 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01398,R07245 RC00096 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N k141_10305_2 1279017.AQYJ01000026_gene202 7.35e-37 129.0 2C79Y@1|root,33267@2|Bacteria,1N7XV@1224|Proteobacteria,1SEFE@1236|Gammaproteobacteria,468HT@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_19717_1 218284.CCDN010000001_gene101 1.44e-21 90.9 2C8MW@1|root,305IT@2|Bacteria,1V5HI@1239|Firmicutes,4HGP6@91061|Bacilli,1ZBX1@1386|Bacillus 91061|Bacilli S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains ylbO - - ko:K06314 - - - - ko00000,ko03000 - - - Myb_DNA-bind_6 k141_19717_2 218284.CCDN010000001_gene100 1.89e-103 300.0 COG0454@1|root,COG0454@2|Bacteria,1V259@1239|Firmicutes,4HFSD@91061|Bacilli,1ZFN4@1386|Bacillus 91061|Bacilli K n-acetyltransferase ylbP - - - - - - - - - - - Acetyltransf_1,Acetyltransf_7 k141_19717_3 1196324.A374_11800 1.79e-13 69.3 COG0439@1|root,COG0439@2|Bacteria,1TP16@1239|Firmicutes,4HA40@91061|Bacilli 91061|Bacilli I Biotin carboxylase accA1 - 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 k141_31399_1 218284.CCDN010000001_gene527 5.94e-137 412.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,4H9S7@91061|Bacilli,1ZB6Y@1386|Bacillus 91061|Bacilli L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A k141_35163_1 218284.CCDN010000005_gene3347 8.37e-55 182.0 COG1972@1|root,COG1972@2|Bacteria,1TRSK@1239|Firmicutes,4HA8N@91061|Bacilli,1ZAW2@1386|Bacillus 91061|Bacilli F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family yutK GO:0003674,GO:0005215,GO:0005337,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0015858,GO:0015931,GO:0015932,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:1901264,GO:1901505,GO:1901642 - ko:K03317 - - - - ko00000 2.A.41 - iYO844.BSU32180 Gate,Nucleos_tra2_C,Nucleos_tra2_N k141_32598_1 218284.CCDN010000006_gene3615 1.02e-182 514.0 COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,4H9R3@91061|Bacilli,1ZCXW@1386|Bacillus 91061|Bacilli F Belongs to the phosphoglycerate kinase family pgk GO:0001871,GO:0002020,GO:0003674,GO:0003824,GO:0004618,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009893,GO:0009986,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019222,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030162,GO:0030193,GO:0030195,GO:0030246,GO:0030247,GO:0030312,GO:0031323,GO:0031325,GO:0032101,GO:0032102,GO:0032268,GO:0032270,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043532,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0045862,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048518,GO:0048519,GO:0048522,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050818,GO:0050819,GO:0050878,GO:0051171,GO:0051173,GO:0051186,GO:0051188,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051917,GO:0051919,GO:0055086,GO:0060255,GO:0061041,GO:0061045,GO:0065007,GO:0065008,GO:0070613,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0080134,GO:0090407,GO:1900046,GO:1900047,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903034,GO:1903035,GO:1903317,GO:1903319,GO:2001065 2.7.2.3 ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01512 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000,ko04147 - - iSB619.SA_RS04145 PGK k141_33952_2 218284.CCDN010000001_gene1674 5.07e-83 254.0 COG0662@1|root,COG0662@2|Bacteria,1V3H4@1239|Firmicutes,4HH1K@91061|Bacilli,1ZFFQ@1386|Bacillus 91061|Bacilli G Cupin domain - - - - - - - - - - - - Cupin_2 k141_14829_1 1042377.AFPJ01000005_gene2470 7.37e-85 265.0 COG4783@1|root,COG4783@2|Bacteria,1QUMJ@1224|Proteobacteria,1T2RP@1236|Gammaproteobacteria,4660W@72275|Alteromonadaceae 1236|Gammaproteobacteria S Zn-dependent protease, contains TPR repeats - - - - - - - - - - - - Peptidase_M48,TPR_16,TPR_2,TPR_8 k141_14829_2 443152.MDG893_11126 4.33e-59 183.0 COG2329@1|root,COG2329@2|Bacteria,1RJ9X@1224|Proteobacteria,1T0VD@1236|Gammaproteobacteria,46D1A@72275|Alteromonadaceae 1236|Gammaproteobacteria S Antibiotic biosynthesis monooxygenase - - - - - - - - - - - - ABM k141_36184_1 218284.CCDN010000006_gene3609 3.89e-108 332.0 COG0557@1|root,COG0557@2|Bacteria,1TQ1G@1239|Firmicutes,4HBBH@91061|Bacilli,1ZBDP@1386|Bacillus 91061|Bacilli K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs rnr - - ko:K12573 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03016,ko03019 - - - OB_RNB,RNB,S1 k141_16071_2 998674.ATTE01000001_gene4034 5.18e-68 222.0 COG0837@1|root,COG0837@2|Bacteria,1MVFI@1224|Proteobacteria,1RNUY@1236|Gammaproteobacteria,460JU@72273|Thiotrichales 72273|Thiotrichales G Belongs to the bacterial glucokinase family - - - - - - - - - - - - Glucokinase k141_16071_3 1279017.AQYJ01000021_gene2857 1.84e-185 541.0 COG1472@1|root,COG1472@2|Bacteria,1MVIV@1224|Proteobacteria,1RMA0@1236|Gammaproteobacteria,465BV@72275|Alteromonadaceae 1236|Gammaproteobacteria G Family 3 - - 3.2.1.21 ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 - R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - GH3 - Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C,Lipase_GDSL_2 k141_9027_1 218284.CCDN010000002_gene2591 5.94e-16 82.8 2ASSK@1|root,31I7S@2|Bacteria,1V7RU@1239|Firmicutes,4HJ2S@91061|Bacilli,1ZDBW@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_13928_1 1116375.VEJY3_11285 6.38e-136 430.0 COG3170@1|root,COG3170@2|Bacteria,1MXV7@1224|Proteobacteria,1RMM5@1236|Gammaproteobacteria,1XUV6@135623|Vibrionales 135623|Vibrionales NU COG3170 Tfp pilus assembly protein FimV - - - ko:K08086 - - - - ko00000 - - - - k141_27027_1 406124.ACPC01000008_gene1632 1.1e-11 64.3 COG0034@1|root,COG0034@2|Bacteria,1TPH3@1239|Firmicutes,4HAXU@91061|Bacilli,1ZCE0@1386|Bacillus 91061|Bacilli F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine purF - 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 - - iSB619.SA_RS05225 GATase_6,GATase_7,Pribosyltran k141_14830_1 370438.PTH_0008 2.06e-15 78.6 COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,2482G@186801|Clostridia,2601Z@186807|Peptococcaceae 186801|Clostridia L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrA - 5.99.1.3 ko:K02469 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseA_C,DNA_topoisoIV k141_24405_2 318586.Pden_5027 1.5e-22 100.0 COG0438@1|root,COG1887@1|root,COG0438@2|Bacteria,COG1887@2|Bacteria,1R8IQ@1224|Proteobacteria,2U842@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1,Glyphos_transf k141_32600_1 1461580.CCAS010000006_gene875 7.35e-37 136.0 COG0510@1|root,COG0510@2|Bacteria,1VB8C@1239|Firmicutes,4HNC9@91061|Bacilli,1ZAQ0@1386|Bacillus 91061|Bacilli M choline kinase involved in LPS biosynthesis - - - - - - - - - - - - APH k141_13929_1 1333856.L686_04500 2.2e-73 247.0 COG1201@1|root,COG1201@2|Bacteria,1MUSW@1224|Proteobacteria,1RSNV@1236|Gammaproteobacteria,1Z0YX@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria L helicase lhr GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - ko:K03724 - - - - ko00000,ko01000,ko03400 - - - DEAD,DEAD_assoc,HTH_42,Helicase_C k141_36185_1 935836.JAEL01000096_gene3512 2.8e-42 142.0 COG0359@1|root,COG0359@2|Bacteria,1V6QG@1239|Firmicutes,4HIKJ@91061|Bacilli,1ZGEE@1386|Bacillus 91061|Bacilli J binds to the 23S rRNA rplI GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02939 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L9_C,Ribosomal_L9_N k141_36185_2 1294265.JCM21738_3241 4.82e-44 157.0 COG3887@1|root,COG3887@2|Bacteria,1TPGP@1239|Firmicutes,4HBVH@91061|Bacilli,1ZCB0@1386|Bacillus 91061|Bacilli T signaling protein consisting of a modified GGDEF domain and a DHH domain yybT - - - - - - - - - - - DHH,DHHA1 k141_35164_2 156889.Mmc1_3533 7.2e-11 62.4 COG1366@1|root,COG1366@2|Bacteria 2|Bacteria T antisigma factor binding spoIIAA - - ko:K04749,ko:K20978 ko02020,ko02025,map02020,map02025 - - - ko00000,ko00001,ko03021 - - - PilZ,STAS,STAS_2 k141_27028_1 1042377.AFPJ01000023_gene657 3.13e-75 255.0 COG1361@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4932@2|Bacteria,1QUEG@1224|Proteobacteria 1224|Proteobacteria M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - - - - - - - - - - SdrD_B k141_23348_1 1279017.AQYJ01000019_gene1482 1.41e-176 504.0 COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,1RN70@1236|Gammaproteobacteria,464FE@72275|Alteromonadaceae 1236|Gammaproteobacteria EGP COG0477 Permeases of the major facilitator superfamily yajR GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - - - - - - - - - - MFS_1,Sugar_tr k141_23348_2 1279017.AQYJ01000019_gene1481 5.04e-96 292.0 COG0836@1|root,COG0836@2|Bacteria,1MV39@1224|Proteobacteria,1RNQI@1236|Gammaproteobacteria,4644C@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the mannose-6-phosphate isomerase type 2 family algA - 2.7.7.13,5.3.1.8 ko:K00971,ko:K16011 ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025 M00114,M00361,M00362 R00885,R01819 RC00002,RC00376 ko00000,ko00001,ko00002,ko01000 - - - MannoseP_isomer,NTP_transferase k141_19718_1 935837.JAEK01000012_gene348 3.81e-14 67.0 2EIIR@1|root,33CA1@2|Bacteria,1VMUM@1239|Firmicutes,4HSC6@91061|Bacilli,1ZJ19@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_17256_2 1116375.VEJY3_11410 1.75e-253 699.0 COG4235@1|root,COG4235@2|Bacteria,1MY4J@1224|Proteobacteria,1RZEA@1236|Gammaproteobacteria,1XSCF@135623|Vibrionales 135623|Vibrionales O COG4235 Cytochrome c biogenesis factor ccmI - - - - - - - - - - - TPR_19 k141_10309_1 218284.CCDN010000001_gene760 2.05e-121 365.0 COG0358@1|root,COG0358@2|Bacteria,1TQ0X@1239|Firmicutes,4HAG2@91061|Bacilli,1ZC16@1386|Bacillus 91061|Bacilli L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG - - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2 k141_22026_2 218284.CCDN010000006_gene3629 1.42e-189 531.0 COG0391@1|root,COG0391@2|Bacteria,1TPNV@1239|Firmicutes,4HA0Z@91061|Bacilli,1ZB2R@1386|Bacillus 91061|Bacilli S Required for morphogenesis under gluconeogenic growth conditions yvcK - - - - - - - - - - - UPF0052 k141_22026_3 218284.CCDN010000006_gene3630 1.14e-60 194.0 COG1660@1|root,COG1660@2|Bacteria,1TPS4@1239|Firmicutes,4H9KM@91061|Bacilli,1ZCWE@1386|Bacillus 91061|Bacilli S Displays ATPase and GTPase activities yvcJ - - ko:K06958 - - - - ko00000,ko03019 - - - ATP_bind_2 k141_13931_1 743719.PaelaDRAFT_0048 2.48e-87 263.0 COG1586@1|root,COG1586@2|Bacteria,1TQ7S@1239|Firmicutes,4HA9C@91061|Bacilli,26S7I@186822|Paenibacillaceae 91061|Bacilli E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine speD - 4.1.1.50 ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 M00034,M00133 R00178 RC00299 ko00000,ko00001,ko00002,ko01000 - - - AdoMet_dc k141_12722_1 1042377.AFPJ01000029_gene535 1.64e-160 474.0 COG5000@1|root,COG5000@2|Bacteria,1QVAT@1224|Proteobacteria,1T324@1236|Gammaproteobacteria,46D3E@72275|Alteromonadaceae 1236|Gammaproteobacteria T His Kinase A (phosphoacceptor) domain - - 2.7.13.3 ko:K02668 ko02020,map02020 M00501 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 - - - HATPase_c,HisKA k141_12722_2 1453501.JELR01000005_gene1785 3.86e-137 403.0 COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,1RNKA@1236|Gammaproteobacteria,464PF@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source nadE - 6.3.1.5,6.3.5.1 ko:K01916,ko:K01950 ko00760,ko01100,map00760,map01100 M00115 R00189,R00257 RC00010,RC00100 ko00000,ko00001,ko00002,ko01000 - - - CN_hydrolase,NAD_synthase k141_29111_1 42565.FP66_07955 5.28e-109 333.0 COG1199@1|root,COG1199@2|Bacteria,1MVCU@1224|Proteobacteria,1RMNX@1236|Gammaproteobacteria,1XIVR@135619|Oceanospirillales 135619|Oceanospirillales KL helicase dinG - 3.6.4.12 ko:K03722 - - - - ko00000,ko01000,ko03400 - - - DEAD,DEAD_2,Helicase_C_2,ResIII k141_29111_2 42565.FP66_07960 2.35e-59 187.0 COG1999@1|root,COG1999@2|Bacteria,1RHJ8@1224|Proteobacteria,1S3NG@1236|Gammaproteobacteria,1XJRX@135619|Oceanospirillales 135619|Oceanospirillales S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems - - - ko:K07152 - - - - ko00000,ko03029 - - - SCO1-SenC k141_24440_2 391598.FBBAL38_00455 5.68e-05 50.1 COG1664@1|root,COG1664@2|Bacteria,4NP7X@976|Bacteroidetes,1I2I0@117743|Flavobacteriia 976|Bacteroidetes M Putative auto-transporter adhesin, head GIN domain - - - - - - - - - - - - DUF2807 k141_27054_1 1294265.JCM21738_3655 1.57e-314 858.0 COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,4H9ZM@91061|Bacilli,1ZBFQ@1386|Bacillus 91061|Bacilli D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine tilS - 2.4.2.8,6.3.4.19 ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 - R01132,R01229,R02142,R09597 RC00063,RC00122,RC02633,RC02634 ko00000,ko00001,ko01000,ko03016 - - - ATP_bind_3,TilS,TilS_C k141_27054_3 997296.PB1_06902 0.0 975.0 COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,4HAJB@91061|Bacilli,1ZBEU@1386|Bacillus 91061|Bacilli O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins ftsH GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0030428,GO:0032502,GO:0042623,GO:0043170,GO:0043934,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - ko:K03798 - M00742 - - ko00000,ko00002,ko01000,ko01002,ko03110 - - - AAA,FtsH_ext,Peptidase_M41 k141_11479_1 749413.E5DV49_9VIRU 2.78e-57 189.0 4QB6U@10239|Viruses,4QUPZ@35237|dsDNA viruses no RNA stage 10239|Viruses S Terminase small subunit - - - - - - - - - - - - - k141_35195_1 314225.ELI_14900 2.28e-106 314.0 COG2801@1|root,COG2801@2|Bacteria,1MVN5@1224|Proteobacteria,2TQK0@28211|Alphaproteobacteria,2K2F6@204457|Sphingomonadales 204457|Sphingomonadales L COG2801 Transposase and inactivated derivatives - - - - - - - - - - - - HTH_21,rve,rve_3 k141_18616_1 1453501.JELR01000001_gene3029 5.54e-74 229.0 COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,1RNME@1236|Gammaproteobacteria,464K2@72275|Alteromonadaceae 1236|Gammaproteobacteria G COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family suhB - 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 - - - Inositol_P k141_18616_2 1042377.AFPJ01000034_gene2386 9.49e-18 80.5 COG0565@1|root,COG0565@2|Bacteria,1N47Y@1224|Proteobacteria,1RPD3@1236|Gammaproteobacteria,465US@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA trmJ - 2.1.1.200 ko:K02533,ko:K15396 - - - - ko00000,ko01000,ko03016 - - - SpoU_methylase k141_792_1 383407.XOC_4064 1.06e-69 237.0 COG3210@1|root,COG3210@2|Bacteria,1MX2K@1224|Proteobacteria,1RNRK@1236|Gammaproteobacteria,1X32X@135614|Xanthomonadales 1236|Gammaproteobacteria U hemagglutinin hemolysin-related protein - - - ko:K15125 ko05133,map05133 - - - ko00000,ko00001,ko00536 - - - DUF769,ESPR,Fil_haemagg,Fil_haemagg_2,Haemagg_act,PT-VENN k141_25744_1 1294265.JCM21738_4674 6.25e-110 317.0 COG1376@1|root,COG1376@2|Bacteria,1V9XU@1239|Firmicutes,4HKDD@91061|Bacilli,1ZGIN@1386|Bacillus 91061|Bacilli S protein conserved in bacteria ykuD - - - - - - - - - - - LysM,YkuD k141_25744_2 1294265.JCM21738_4675 1.26e-14 73.2 COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,4HA3G@91061|Bacilli,1ZAVY@1386|Bacillus 91061|Bacilli T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,PAS_4,PAS_9 k141_6633_1 1211817.CCAT010000085_gene1901 4.17e-19 87.0 COG0667@1|root,COG0667@2|Bacteria,1V53W@1239|Firmicutes,24KNB@186801|Clostridia 186801|Clostridia C Aldo/keto reductase family - - - - - - - - - - - - Aldo_ket_red k141_6633_2 218284.CCDN010000001_gene1620 6.81e-57 186.0 COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,4HDG0@91061|Bacilli,1ZBE9@1386|Bacillus 91061|Bacilli C Belongs to the citrate synthase family citA - 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 - - - Citrate_synt k141_37401_1 674977.VMC_42130 1.07e-46 160.0 COG4597@1|root,COG4597@2|Bacteria,1MV0S@1224|Proteobacteria,1RN6V@1236|Gammaproteobacteria,1XSEY@135623|Vibrionales 135623|Vibrionales P COG4597 ABC-type amino acid transport system, permease component aapQ - - ko:K09970 ko02010,map02010 M00232 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.18,3.A.1.3.7,3.A.1.3.8 - - BPD_transp_1 k141_37401_2 1116375.VEJY3_07690 2.02e-244 671.0 COG0834@1|root,COG0834@2|Bacteria,1MV5D@1224|Proteobacteria,1RNJJ@1236|Gammaproteobacteria,1XSSI@135623|Vibrionales 135623|Vibrionales ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain aapJ - - ko:K09969 ko02010,map02010 M00232 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.18,3.A.1.3.7,3.A.1.3.8 - - SBP_bac_3 k141_30221_2 930169.B5T_00143 2.2e-209 594.0 COG1292@1|root,COG1292@2|Bacteria,1QSN7@1224|Proteobacteria,1RYYU@1236|Gammaproteobacteria,1XP1T@135619|Oceanospirillales 135619|Oceanospirillales M BCCT, betaine/carnitine/choline family transporter - - - - - - - - - - - - BCCT k141_11480_1 1051646.VITU9109_04022 8.67e-77 232.0 COG3981@1|root,COG3981@2|Bacteria,1RIGX@1224|Proteobacteria,1S7UW@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_3 k141_27055_1 1499680.CCFE01000018_gene1198 9.66e-29 110.0 COG0596@1|root,COG0596@2|Bacteria,1TS4C@1239|Firmicutes,4HB6G@91061|Bacilli,1ZAU9@1386|Bacillus 91061|Bacilli S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) menH GO:0003674,GO:0003824,GO:0016787 4.2.99.20 ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R08166 RC02148,RC02475 ko00000,ko00001,ko00002,ko01000 - - - Abhydrolase_1 k141_27055_2 1294265.JCM21738_2986 4.51e-98 286.0 COG1165@1|root,COG1165@2|Bacteria,1TRDB@1239|Firmicutes,4HC48@91061|Bacilli,1ZANU@1386|Bacillus 91061|Bacilli H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) menD - 2.2.1.9 ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R08165 RC02186 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS05085 TPP_enzyme_C,TPP_enzyme_M_2,TPP_enzyme_N k141_12739_2 1453501.JELR01000002_gene329 1.17e-33 129.0 COG3063@1|root,COG3063@2|Bacteria,1R0M2@1224|Proteobacteria,1T4K4@1236|Gammaproteobacteria,46DCA@72275|Alteromonadaceae 1236|Gammaproteobacteria NU Tetratricopeptide repeat - - - - - - - - - - - - TPR_16,TPR_8,Transglut_core k141_6634_1 574376.BAMA_13915 4.11e-40 143.0 COG1408@1|root,COG1408@2|Bacteria,1V494@1239|Firmicutes,4HH1B@91061|Bacilli,1ZBFW@1386|Bacillus 91061|Bacilli S Calcineurin-like phosphoesterase superfamily domain ypbG - - ko:K07098 - - - - ko00000 - - - Metallophos,Metallophos_2 k141_22031_2 498211.CJA_0162 1.2e-61 194.0 COG3160@1|root,COG3160@2|Bacteria,1RHBB@1224|Proteobacteria,1S420@1236|Gammaproteobacteria,1FH6F@10|Cellvibrio 1236|Gammaproteobacteria K Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ rsd GO:0000988,GO:0000989,GO:0003674,GO:0008150,GO:0009889,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2001141 - ko:K07740 - - - - ko00000 - - - Rsd_AlgQ k141_22031_3 1279017.AQYJ01000027_gene1917 7.56e-124 361.0 COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,1RPMP@1236|Gammaproteobacteria,466UT@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0545 FKBP-type peptidyl-prolyl cis-trans isomerases 1 mip - 5.2.1.8 ko:K03772,ko:K03773 - - - - ko00000,ko01000,ko03110 - - - FKBP_C,FKBP_N k141_9048_1 997296.PB1_10097 2.11e-46 162.0 29H5Q@1|root,30439@2|Bacteria,1V63Q@1239|Firmicutes,4HHR2@91061|Bacilli,1ZE9T@1386|Bacillus 91061|Bacilli S Nuclease-related domain - - - - - - - - - - - - NERD k141_10333_1 1236973.JCM9157_1071 7.74e-124 365.0 COG3314@1|root,COG3314@2|Bacteria,1TR35@1239|Firmicutes,4HAB6@91061|Bacilli,1ZARZ@1386|Bacillus 91061|Bacilli S protein conserved in bacteria - - - - - - - - - - - - Gate k141_27830_1 1196028.ALEF01000073_gene2232 6.76e-32 112.0 2EE9Q@1|root,33845@2|Bacteria,1VJK0@1239|Firmicutes,4HNNJ@91061|Bacilli,4C71D@84406|Virgibacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_5533_1 1379270.AUXF01000002_gene1784 4.12e-76 248.0 COG1158@1|root,COG1158@2|Bacteria,1ZTA0@142182|Gemmatimonadetes 142182|Gemmatimonadetes F Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template - - - ko:K03628 ko03018,map03018 - - - ko00000,ko00001,ko03019,ko03021 - - - ATP-synt_ab,Rho_RNA_bind k141_6635_1 218284.CCDN010000001_gene110 2.51e-61 203.0 2D69E@1|root,32TKR@2|Bacteria,1VCRS@1239|Firmicutes,4HMFA@91061|Bacilli,1ZAXR@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - Cu_amine_oxidN1 k141_9049_1 1042377.AFPJ01000007_gene1906 1e-83 274.0 COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,1RNCU@1236|Gammaproteobacteria,464IX@72275|Alteromonadaceae 1236|Gammaproteobacteria L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd GO:0000715,GO:0000716,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006283,GO:0006289,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008094,GO:0008150,GO:0008152,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0015616,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031326,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0043175,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051276,GO:0051716,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF k141_35197_1 218284.CCDN010000004_gene3088 1.37e-114 344.0 COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,4HA1G@91061|Bacilli,1ZASC@1386|Bacillus 91061|Bacilli G COG0366 Glycosidases malL GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.2.1.10 ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00801,R01718,R01791,R06199 RC00028,RC00059,RC00077,RC00451 ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,Malt_amylase_C k141_9313_4 870967.VIS19158_23040 7.5e-26 104.0 COG3019@1|root,COG3019@2|Bacteria,1MZ9V@1224|Proteobacteria,1S9CQ@1236|Gammaproteobacteria,1XX3N@135623|Vibrionales 135623|Vibrionales S Protein of unknown function, DUF copG - - - - - - - - - - - DUF411 k141_9313_5 1279017.AQYJ01000029_gene3846 1.23e-138 402.0 COG4301@1|root,COG4301@2|Bacteria,1MUCG@1224|Proteobacteria,1RR44@1236|Gammaproteobacteria,466C6@72275|Alteromonadaceae 1236|Gammaproteobacteria S Histidine-specific methyltransferase, SAM-dependent egtD - - - - - - - - - - - Methyltransf_33 k141_9313_6 1279017.AQYJ01000029_gene3845 3.63e-221 620.0 COG1262@1|root,COG1262@2|Bacteria,1MUNC@1224|Proteobacteria,1RQI4@1236|Gammaproteobacteria,465KE@72275|Alteromonadaceae 1236|Gammaproteobacteria S DinB superfamily egtB - - - - - - - - - - - DinB_2,FGE-sulfatase k141_9313_7 1042377.AFPJ01000007_gene1790 0.0 1277.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MWKN@1224|Proteobacteria,1T3IM@1236|Gammaproteobacteria,465P2@72275|Alteromonadaceae 1236|Gammaproteobacteria P TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_9313_8 1042377.AFPJ01000007_gene1789 0.0 1129.0 COG2366@1|root,COG2366@2|Bacteria,1MVMH@1224|Proteobacteria,1RPRP@1236|Gammaproteobacteria,464U8@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG2366 Protein related to penicillin acylase quiP - 3.5.1.11,3.5.1.97 ko:K01434,ko:K07116 ko00311,ko01130,map00311,map01130 - R02170 RC00166,RC00328 ko00000,ko00001,ko01000,ko01002 - - - Penicil_amidase k141_9313_9 1453501.JELR01000001_gene2314 1.87e-37 127.0 2ETJP@1|root,33M3F@2|Bacteria,1NH39@1224|Proteobacteria,1SGTE@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_9313_10 1279017.AQYJ01000029_gene3841 2.96e-246 686.0 COG0007@1|root,COG1648@1|root,COG0007@2|Bacteria,COG1648@2|Bacteria,1MUI0@1224|Proteobacteria,1RM9V@1236|Gammaproteobacteria,4645Q@72275|Alteromonadaceae 1236|Gammaproteobacteria H Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme cysG - 1.3.1.76,2.1.1.107,4.99.1.4 ko:K02302,ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02864,R03194,R03947 RC00003,RC00871,RC01012,RC01034 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_3999 CysG_dimeriser,NAD_binding_7,Sirohm_synth_M,TP_methylase k141_9313_11 1279017.AQYJ01000029_gene3840 1.27e-263 727.0 COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,1RNAQ@1236|Gammaproteobacteria,4642I@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) serS GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004828,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006434,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0010467,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iSDY_1059.SDY_2368 Seryl_tRNA_N,tRNA-synt_2b k141_9313_12 1279017.AQYJ01000029_gene3839 1.29e-62 194.0 COG0239@1|root,COG0239@2|Bacteria,1MZNH@1224|Proteobacteria,1S8RQ@1236|Gammaproteobacteria,467ZU@72275|Alteromonadaceae 1236|Gammaproteobacteria D Important for reducing fluoride concentration in the cell, thus reducing its toxicity crcB GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - ko:K06199 - - - - ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 - - CRCB k141_9313_13 1279017.AQYJ01000029_gene3838 1.61e-259 719.0 COG2256@1|root,COG2256@2|Bacteria,1MUVS@1224|Proteobacteria,1RPBY@1236|Gammaproteobacteria,465ZV@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase rarA GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0030894,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576 - ko:K07478 - - - - ko00000 - - - AAA,AAA_assoc_2,MgsA_C,RuvB_N k141_23655_1 1116375.VEJY3_07835 0.0 1160.0 COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,1RR14@1236|Gammaproteobacteria,1XU57@135623|Vibrionales 135623|Vibrionales I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases prpE - 6.2.1.17 ko:K01908 ko00640,ko01100,map00640,map01100 - R00926,R01354 RC00004,RC00043,RC00070,RC02816 ko00000,ko00001,ko01000,ko01004 - - - ACAS_N,AMP-binding,AMP-binding_C k141_23655_2 223926.28806634 2.27e-93 275.0 COG0454@1|root,COG0456@2|Bacteria,1N2EC@1224|Proteobacteria,1RS2A@1236|Gammaproteobacteria,1XXK0@135623|Vibrionales 135623|Vibrionales K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - - - - - - - - - - Acetyltransf_1 k141_34151_1 1453501.JELR01000005_gene1705 1.68e-62 200.0 COG1521@1|root,COG1521@2|Bacteria,1MUYA@1224|Proteobacteria,1S99V@1236|Gammaproteobacteria,467TT@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis coaX - 2.7.1.33 ko:K03525 ko00770,ko01100,map00770,map01100 M00120 R02971,R03018,R04391 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Pan_kinase k141_19920_1 10736.A0A1P8CWS8_BPPHT 1.19e-05 53.1 4QFX2@10239|Viruses,4QZD5@35237|dsDNA viruses no RNA stage,4QQCP@28883|Caudovirales 28883|Caudovirales S RNA-directed RNA polymerase activity - - - - - - - - - - - - - k141_30339_2 218284.CCDN010000001_gene743 7.32e-11 62.8 COG1030@1|root,COG1030@2|Bacteria,1TR54@1239|Firmicutes,4H9P9@91061|Bacilli,1ZCTF@1386|Bacillus 91061|Bacilli O COG1030 Membrane-bound serine protease (ClpP class) yqeZ - - ko:K07403 - - - - ko00000 - - - NfeD,SDH_sah k141_32843_1 1120963.KB894493_gene3070 1.52e-07 57.0 COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,1RSE6@1236|Gammaproteobacteria,2PZWA@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamD GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - ko:K05807 - - - - ko00000,ko02000 1.B.33.1 - - YfiO k141_37548_2 1453501.JELR01000002_gene1432 1.03e-67 213.0 COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,1RN8W@1236|Gammaproteobacteria,464TQ@72275|Alteromonadaceae 1236|Gammaproteobacteria BQ COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein - - - - - - - - - - - - Hist_deacetyl k141_22311_1 1219076.N646_1503 5.37e-197 555.0 COG0554@1|root,COG0554@2|Bacteria,1MUP7@1224|Proteobacteria,1RMAF@1236|Gammaproteobacteria,1XUKJ@135623|Vibrionales 135623|Vibrionales F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate glpK GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 - R00847 RC00002,RC00017 ko00000,ko00001,ko01000,ko04147 - - - FGGY_C,FGGY_N k141_25954_1 236097.ADG881_2203 1.05e-164 469.0 COG0715@1|root,COG0715@2|Bacteria,1MVJA@1224|Proteobacteria,1RUI0@1236|Gammaproteobacteria,1XIZT@135619|Oceanospirillales 135619|Oceanospirillales P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1,NMT1_2 k141_25954_2 1120970.AUBZ01000005_gene427 1.4e-134 388.0 COG0600@1|root,COG0600@2|Bacteria,1MWDJ@1224|Proteobacteria,1RS50@1236|Gammaproteobacteria,464VG@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component tauC - - ko:K02050 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - BPD_transp_1 k141_25954_3 1190603.AJYD01000025_gene447 2.83e-113 334.0 COG1116@1|root,COG1116@2|Bacteria,1MWZG@1224|Proteobacteria,1RN60@1236|Gammaproteobacteria,1Y2HU@135623|Vibrionales 135623|Vibrionales P ATPases associated with a variety of cellular activities - - - - - - - - - - - - ABC_tran k141_25954_4 1298593.TOL_2416 3.47e-90 271.0 COG3665@1|root,COG3665@2|Bacteria,1N2KR@1224|Proteobacteria,1RN5H@1236|Gammaproteobacteria,1XIHT@135619|Oceanospirillales 135619|Oceanospirillales S Domain of unknown function (DUF1989) - - - ko:K09967 - - - - ko00000 - - - DUF1989 k141_27340_1 1453501.JELR01000002_gene907 3.26e-41 151.0 COG3523@1|root,COG3523@2|Bacteria,1MV3D@1224|Proteobacteria,1RPQ2@1236|Gammaproteobacteria,464BZ@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria icmF - - ko:K11891 ko02025,ko03070,map02025,map03070 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - IcmF-related,IcmF_C,ImcF-related_N k141_27340_2 1279017.AQYJ01000027_gene1549 3.24e-82 251.0 COG3913@1|root,COG3913@2|Bacteria,1N01G@1224|Proteobacteria,1S6EQ@1236|Gammaproteobacteria,467UX@72275|Alteromonadaceae 1236|Gammaproteobacteria S Uncharacterized protein conserved in bacteria (DUF2094) impM - - ko:K11890 ko02025,map02025 - - - ko00000,ko00001,ko02044 - - - DUF2094 k141_9315_1 913865.DOT_2865 1.49e-06 52.4 COG1309@1|root,COG1309@2|Bacteria,1VGTE@1239|Firmicutes,24RSU@186801|Clostridia 186801|Clostridia K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N k141_29337_1 1405.DJ92_1866 4.29e-39 139.0 COG0327@1|root,COG0327@2|Bacteria,1V149@1239|Firmicutes,4I7AR@91061|Bacilli,1ZFDI@1386|Bacillus 91061|Bacilli S NIF3 (NGG1p interacting factor 3) - - - - - - - - - - - - NIF3 k141_29337_2 265729.GS18_0201495 1.34e-65 201.0 COG3795@1|root,COG3795@2|Bacteria,1VDPN@1239|Firmicutes,4HKKT@91061|Bacilli,1ZH8J@1386|Bacillus 91061|Bacilli S YCII-related domain - - - - - - - - - - - - YCII k141_23686_1 218284.CCDN010000006_gene3603 1.13e-09 59.3 COG0642@1|root,COG2205@2|Bacteria,1V10X@1239|Firmicutes,4HAU7@91061|Bacilli,1ZB6A@1386|Bacillus 91061|Bacilli T Histidine kinase - - - - - - - - - - - - HAMP,HATPase_c,HisKA k141_1000_2 1279017.AQYJ01000022_gene2694 4.46e-39 142.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,465Q7@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - - - - - - - - - - HTH_8,Response_reg,Sigma54_activat k141_27987_1 1347086.CCBA010000022_gene2867 5.82e-81 253.0 COG1404@1|root,COG1404@2|Bacteria,1TSRI@1239|Firmicutes,4HBFB@91061|Bacilli,1ZCQD@1386|Bacillus 91061|Bacilli O Subtilase family - - 3.4.21.62 ko:K01342 ko02024,map02024 - - - ko00000,ko00001,ko01000,ko01002,ko03110 - - - Peptidase_S8 k141_25992_1 218284.CCDN010000001_gene1244 1.26e-71 229.0 COG0534@1|root,COG0534@2|Bacteria,1TP5U@1239|Firmicutes,4HA4W@91061|Bacilli,1ZAX6@1386|Bacillus 91061|Bacilli V Multidrug efflux pump norM GO:0003674,GO:0005215,GO:0006810,GO:0006855,GO:0008150,GO:0015238,GO:0015893,GO:0022857,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0046677,GO:0050896,GO:0051179,GO:0051234,GO:0055085 - ko:K03327 - - - - ko00000,ko02000 2.A.66.1 - - MatE k141_6937_2 1283337.TMP_BPHA1 1.55e-55 193.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QHYN@10662|Myoviridae 10662|Myoviridae S amidase activity - - - - - - - - - - - - - k141_6937_3 587753.EY04_05485 5.04e-22 87.4 COG5004@1|root,COG5004@2|Bacteria 2|Bacteria U Tail protein - - - - - - - - - - - - Phage_tail_X k141_3174_1 379731.PST_2967 2.18e-44 154.0 COG3145@1|root,COG3145@2|Bacteria,1RGXU@1224|Proteobacteria,1S6DD@1236|Gammaproteobacteria,1YZQX@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria L COG3145 Alkylated DNA repair protein alkB - - - - - - - - - - - 2OG-FeII_Oxy_2 k141_3174_2 1279017.AQYJ01000025_gene616 1.3e-25 102.0 COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,1RNXK@1236|Gammaproteobacteria,465JA@72275|Alteromonadaceae 1236|Gammaproteobacteria M cell wall formation murB - 1.3.1.98 ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R03191,R03192 RC02639 ko00000,ko00001,ko01000,ko01011 - - - FAD_binding_4,MurB_C k141_18975_1 218284.CCDN010000002_gene2038 5.32e-133 402.0 COG0457@1|root,COG0457@2|Bacteria,1UATF@1239|Firmicutes,4HE1D@91061|Bacilli,1ZBPM@1386|Bacillus 91061|Bacilli S ATPase. Has a role at an early stage in the morphogenesis of the spore coat - - - - - - - - - - - - Dynamin_N,TPR_8 k141_23687_1 1294265.JCM21738_1649 5.27e-132 376.0 COG0118@1|root,COG0118@2|Bacteria,1TQT0@1239|Firmicutes,4HFXQ@91061|Bacilli,1ZBC4@1386|Bacillus 91061|Bacilli E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR hisH GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - - GATase k141_1904_1 218284.CCDN010000001_gene1002 2.99e-66 205.0 COG0835@1|root,COG0835@2|Bacteria,1V428@1239|Firmicutes,4HI77@91061|Bacilli,1ZFHY@1386|Bacillus 91061|Bacilli NT COG0835 Chemotaxis signal transduction protein - - - ko:K03408 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - CheW k141_11715_2 218284.CCDN010000001_gene969 3.22e-120 351.0 COG0142@1|root,COG0142@2|Bacteria,1TPQY@1239|Firmicutes,4HA8E@91061|Bacilli,1ZC4G@1386|Bacillus 91061|Bacilli H Belongs to the FPP GGPP synthase family ispA GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0071704,GO:1901576 2.5.1.1,2.5.1.10,2.5.1.29 ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00366 R01658,R02003,R02061 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 - - - polyprenyl_synt k141_32880_1 218284.CCDN010000001_gene1183 2.16e-80 239.0 COG1321@1|root,COG1321@2|Bacteria,1V3IS@1239|Firmicutes,4HH06@91061|Bacilli,1ZFKR@1386|Bacillus 91061|Bacilli K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon mntR - - ko:K03709 - - - - ko00000,ko03000 - - - Fe_dep_repr_C,Fe_dep_repress,FeoA k141_32880_2 218284.CCDN010000001_gene1185 1.99e-27 100.0 2BM31@1|root,32FK5@2|Bacteria,1UAUV@1239|Firmicutes,4IM7Q@91061|Bacilli,1ZJF4@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - DUF3892 k141_5725_1 1196029.ALIM01000033_gene1494 9.99e-77 249.0 COG0476@1|root,COG0476@2|Bacteria,1UZJC@1239|Firmicutes,4HB2K@91061|Bacilli,1ZBN2@1386|Bacillus 91061|Bacilli H bacteriocin maturation protein - - - - - - - - - - - - - k141_3175_1 1294265.JCM21738_3347 4.8e-42 146.0 COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,4HA4E@91061|Bacilli,1ZB72@1386|Bacillus 91061|Bacilli P Belongs to the ABC transporter superfamily - - - ko:K02031 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - ABC_tran,oligo_HPY k141_6939_1 441769.ABFU01000050_gene3949 6.98e-109 321.0 COG1075@1|root,COG1075@2|Bacteria,1TQFF@1239|Firmicutes,4HDQN@91061|Bacilli,1ZCCU@1386|Bacillus 91061|Bacilli S acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - - - - - - - - - - PGAP1 k141_25994_1 414684.RC1_2113 8.18e-44 160.0 COG1429@1|root,COG1429@2|Bacteria,1MU5W@1224|Proteobacteria,2TQVD@28211|Alphaproteobacteria,2JQYC@204441|Rhodospirillales 204441|Rhodospirillales H Domain of unknown function (DUF3479) bchH - 6.6.1.1 ko:K03403 ko00860,ko01100,ko01110,map00860,map01100,map01110 - R03877 RC01012 ko00000,ko00001,ko01000 - - - CobN-Mg_chel,DUF3479 k141_25994_2 314270.RB2083_571 7.53e-17 79.3 COG2710@1|root,COG2710@2|Bacteria,1MWQ4@1224|Proteobacteria,2TSTQ@28211|Alphaproteobacteria,3ZI0W@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria H Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex bchB - 1.3.7.7 ko:K04039 ko00860,ko01100,ko01110,map00860,map01100,map01110 - R06282 RC01008 ko00000,ko00001,ko01000 - - - Oxidored_nitro,PCP_red k141_34178_1 665952.HMPREF1015_00356 4.19e-16 73.2 2A1KA@1|root,30PU9@2|Bacteria,1UB4E@1239|Firmicutes,4IMH0@91061|Bacilli,1ZK4Y@1386|Bacillus 91061|Bacilli S YrhC-like protein - - - - - - - - - - - - YrhC k141_22345_1 218284.CCDN010000001_gene546 1.33e-150 429.0 COG1363@1|root,COG1363@2|Bacteria,1TNZT@1239|Firmicutes,4H9SM@91061|Bacilli,1ZD06@1386|Bacillus 91061|Bacilli G COG1363 Cellulase M and related proteins ysdC - - - - - - - - - - - Peptidase_M42 k141_22345_2 218284.CCDN010000001_gene547 2.77e-115 333.0 COG1335@1|root,COG1335@2|Bacteria,1V2DX@1239|Firmicutes,4HJMV@91061|Bacilli,1ZGBB@1386|Bacillus 91061|Bacilli Q Isochorismatase family - - - - - - - - - - - - Isochorismatase k141_12901_1 1279017.AQYJ01000028_gene2451 6.8e-224 649.0 COG3468@1|root,COG3468@2|Bacteria,1R8WV@1224|Proteobacteria 1224|Proteobacteria MU outer membrane autotransporter barrel domain - - - ko:K19231 - - - - ko00000,ko02000 1.B.12 - - Autotransporter,Pertactin k141_12901_2 314278.NB231_15358 5.27e-201 568.0 COG2270@1|root,COG2270@2|Bacteria,1MWXB@1224|Proteobacteria,1S03J@1236|Gammaproteobacteria,1WYH5@135613|Chromatiales 135613|Chromatiales S Major facilitator superfamily - - - ko:K06902 ko04138,map04138 - - - ko00000,ko00001,ko02000,ko04131 2.A.1.24,9.A.15.1 - - ATG22 k141_1905_1 861299.J421_2767 1.16e-113 364.0 COG0085@1|root,COG0085@2|Bacteria,1ZSQH@142182|Gemmatimonadetes 142182|Gemmatimonadetes K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoB - 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 k141_16291_1 1301098.PKB_5472 3.88e-85 283.0 COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,1RMW9@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Cellobiose phosphorylase chbP - 2.4.1.20,2.4.1.280 ko:K00702,ko:K13688,ko:K18675 ko00500,ko00520,ko01100,map00500,map00520,map01100 - R00952,R09942 RC00049 ko00000,ko00001,ko01000,ko01003 - GH94,GT36,GT84 - Glyco_hydro_36,Glyco_transf_36,Glycoamylase k141_9359_1 218284.CCDN010000002_gene2254 3.47e-231 646.0 COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TPJ8@1239|Firmicutes,4HA8X@91061|Bacilli,1ZC2B@1386|Bacillus 91061|Bacilli G IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar ptsG - 2.7.1.208 ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 M00265,M00266,M00268,M00270,M00272,M00303,M00806 R02738,R02780,R04111,R04394,R05132,R08559 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.1,4.A.1.1.11,4.A.1.1.12 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC k141_19949_2 1294265.JCM21738_3221 7.99e-117 337.0 COG0357@1|root,COG0357@2|Bacteria,1TPBT@1239|Firmicutes,4HAAZ@91061|Bacilli,1ZAWG@1386|Bacillus 91061|Bacilli J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA rsmG GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 ko:K03501 - - - - ko00000,ko01000,ko03009,ko03036 - - - GidB k141_6941_1 1384065.JAGS01000001_gene3108 1.88e-29 120.0 COG0270@1|root,COG0270@2|Bacteria,1V3W2@1239|Firmicutes,24HK1@186801|Clostridia,3WNCG@541000|Ruminococcaceae 186801|Clostridia L C-5 cytosine-specific DNA methylase - - 2.1.1.37 ko:K17398 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko03032,ko03036 - - - DNA_methylase k141_25995_1 1347086.CCBA010000025_gene3108 1.14e-21 94.7 COG1131@1|root,COG1131@2|Bacteria,1TQEV@1239|Firmicutes,4HBHF@91061|Bacilli,1ZBR2@1386|Bacillus 91061|Bacilli V ABC transporter, ATP-binding protein yxlF - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 k141_15054_1 1116375.VEJY3_21771 5.13e-234 647.0 COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,1RP4D@1236|Gammaproteobacteria,1XW5K@135623|Vibrionales 135623|Vibrionales E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine - - 4.2.1.20 ko:K06001 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - PALP k141_15054_2 1224318.DT73_18825 3.44e-63 205.0 COG2084@1|root,COG2084@2|Bacteria 2|Bacteria I phosphogluconate dehydrogenase (decarboxylating) activity yfjR - 1.1.1.31 ko:K00020 ko00280,ko01100,map00280,map01100 - R05066 RC00099 ko00000,ko00001,ko01000 - - - NAD_binding_11,NAD_binding_2 k141_22347_1 42565.FP66_07280 2.01e-133 399.0 COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,1RMAP@1236|Gammaproteobacteria,1XHV8@135619|Oceanospirillales 135619|Oceanospirillales M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamA - - ko:K07277 - - - - ko00000,ko02000,ko03029 1.B.33 - - Bac_surface_Ag,POTRA k141_23692_1 218284.CCDN010000002_gene2611 5.11e-57 179.0 COG2832@1|root,COG2832@2|Bacteria,1VEWF@1239|Firmicutes,4HHE4@91061|Bacilli,1ZQHF@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF454) - - - ko:K09790 - - - - ko00000 - - - DUF454 k141_35440_1 743836.AYNA01000054_gene82 3.79e-59 194.0 COG0543@1|root,COG0543@2|Bacteria,1R6QZ@1224|Proteobacteria,2V487@28211|Alphaproteobacteria,36ZQF@31993|Methylocystaceae 28211|Alphaproteobacteria CH Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B - - - - - - - - - - - - DHODB_Fe-S_bind,NAD_binding_1 k141_35440_2 1279017.AQYJ01000025_gene477 7.66e-72 220.0 COG0664@1|root,COG0664@2|Bacteria,1RII7@1224|Proteobacteria,1S7IH@1236|Gammaproteobacteria 1236|Gammaproteobacteria T COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - - - - - - - - - - cNMP_binding k141_35440_3 1279017.AQYJ01000025_gene478 9.63e-118 347.0 COG0479@1|root,COG0479@2|Bacteria,1QVWG@1224|Proteobacteria,1RNMQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria C 4Fe-4S dicluster domain asrA - - ko:K16950 ko00920,ko01120,map00920,map01120 - R00858,R10146 RC00065 ko00000,ko00001 - - - Fer4_22 k141_18976_2 1279017.AQYJ01000018_gene771 3.47e-267 735.0 COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,1RN1G@1236|Gammaproteobacteria,465C7@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the aspartokinase family lysC GO:0003674,GO:0003824,GO:0004072,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0044237 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,ACT,ACT_7 k141_19950_1 42565.FP66_06285 4.9e-158 452.0 COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,1RMAY@1236|Gammaproteobacteria,1XI9W@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate proA - 1.2.1.41 ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 M00015 R03313 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_9361_1 234267.Acid_1347 2.63e-67 226.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,3Y3X3@57723|Acidobacteria 57723|Acidobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k141_23693_1 177439.DP1118 6.58e-36 140.0 COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,42NAW@68525|delta/epsilon subdivisions,2WISU@28221|Deltaproteobacteria,2MIYJ@213118|Desulfobacterales 28221|Deltaproteobacteria K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoC - 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 k141_11718_1 1279017.AQYJ01000027_gene1625 1.31e-73 234.0 COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,1RQDA@1236|Gammaproteobacteria,4666A@72275|Alteromonadaceae 1236|Gammaproteobacteria T signal transduction protein with a C-terminal ATPase domain algZ - 2.7.13.3 ko:K08082 ko02020,map02020 M00493 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - His_kinase k141_1002_1 218284.CCDN010000001_gene704 6.43e-144 408.0 COG0775@1|root,COG0775@2|Bacteria,1U7WK@1239|Firmicutes,4HB8K@91061|Bacilli,1ZB7T@1386|Bacillus 91061|Bacilli E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively mtnN - 3.2.2.9 ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 M00034,M00609 R00194,R01401 RC00063,RC00318 ko00000,ko00001,ko00002,ko01000 - - - PNP_UDP_1 k141_6942_1 1294265.JCM21738_2725 1.62e-76 240.0 COG1875@1|root,COG1875@2|Bacteria,1UHTD@1239|Firmicutes,4HA4V@91061|Bacilli,1ZDIF@1386|Bacillus 91061|Bacilli T ATPase related to phosphate starvation-inducible protein PhoH ylaK - - ko:K07175 - - - - ko00000 - - - PIN_4,PhoH k141_6942_2 1294265.JCM21738_2724 1.26e-51 167.0 2A3AP@1|root,30RSQ@2|Bacteria,1VA69@1239|Firmicutes,4HKTQ@91061|Bacilli,1ZFXZ@1386|Bacillus 91061|Bacilli S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) ylaJ - - - - - - - - - - - Spore_YhcN_YlaJ k141_7950_1 1238450.VIBNISOn1_370008 1.06e-271 749.0 COG1840@1|root,COG1840@2|Bacteria,1MXZ8@1224|Proteobacteria,1RPPC@1236|Gammaproteobacteria,1XSDQ@135623|Vibrionales 135623|Vibrionales P ABC-type Fe3 transport system, periplasmic component - - - - - - - - - - - - SBP_bac_6 k141_7950_2 1238450.VIBNISOn1_370009 9.87e-230 641.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1XSE5@135623|Vibrionales 135623|Vibrionales T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - ko:K10126 ko02020,map02020 M00504 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat k141_1908_1 1385511.N783_19750 8.19e-61 197.0 COG5621@1|root,COG5621@2|Bacteria,1VMAB@1239|Firmicutes,4HUVV@91061|Bacilli 91061|Bacilli S Lipocalin-like domain - - - - - - - - - - - - CrtC,Lipocalin_9 k141_5727_1 1169144.KB910940_gene2537 3.19e-112 342.0 COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4H9ZK@91061|Bacilli,1ZCFC@1386|Bacillus 91061|Bacilli S ABC transporter - - - - - - - - - - - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn k141_12903_1 218284.CCDN010000001_gene991 2.26e-86 263.0 COG1703@1|root,COG1703@2|Bacteria,1TQT4@1239|Firmicutes,4H9ZJ@91061|Bacilli,1ZC78@1386|Bacillus 91061|Bacilli E periplasmic protein kinase ArgK and related GTPases of G3E family argK - - ko:K07588 - - - - ko00000,ko01000 - - - ArgK k141_6943_1 1423321.AS29_12080 4.6e-26 108.0 COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HA0V@91061|Bacilli,1ZBTK@1386|Bacillus 91061|Bacilli O Belongs to the ClpA ClpB family clpE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03697,ko:K04086 - - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,UVR k141_30357_1 218284.CCDN010000001_gene1050 4.62e-81 253.0 COG0019@1|root,COG0019@2|Bacteria,1TPE9@1239|Firmicutes,4H9XW@91061|Bacilli,1ZD43@1386|Bacillus 91061|Bacilli E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine lysA - 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N,Orn_DAP_Arg_deC k141_24672_1 1294265.JCM21738_1942 4.33e-172 481.0 28IPR@1|root,2Z8PJ@2|Bacteria,1TPYR@1239|Firmicutes,4HBI7@91061|Bacilli,1ZAX0@1386|Bacillus 91061|Bacilli S Belongs to the UPF0736 family yjbA - - - - - - - - - - - DUF3603 k141_24672_2 1294265.JCM21738_1941 1.28e-32 121.0 COG0180@1|root,COG0180@2|Bacteria,1TPY7@1239|Firmicutes,4HA1K@91061|Bacilli,1ZCUY@1386|Bacillus 91061|Bacilli J Tryptophanyl-tRNA synthetase trpS - 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1b k141_18977_1 1294265.JCM21738_3125 2.65e-101 300.0 COG1173@1|root,COG1173@2|Bacteria,1V7EU@1239|Firmicutes,4HJGN@91061|Bacilli,1ZFJU@1386|Bacillus 91061|Bacilli EP ABC-type dipeptide oligopeptide nickel transport systems, permease components - - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 k141_18977_2 1294265.JCM21738_3124 4.95e-53 170.0 COG0601@1|root,COG0601@2|Bacteria,1VB92@1239|Firmicutes,4IEZQ@91061|Bacilli,1ZHIU@1386|Bacillus 91061|Bacilli EP Binding-protein-dependent transport system inner membrane component - - - ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - BPD_transp_1 k141_32884_1 1279017.AQYJ01000025_gene567 1.16e-87 285.0 COG1629@1|root,COG4771@2|Bacteria,1N6JG@1224|Proteobacteria,1RP10@1236|Gammaproteobacteria,465FE@72275|Alteromonadaceae 1236|Gammaproteobacteria P Carboxypeptidase regulatory-like domain - - - - - - - - - - - - CarboxypepD_reg,Plug,TonB_dep_Rec k141_36364_1 1279017.AQYJ01000028_gene2137 9.12e-176 517.0 COG0308@1|root,COG0308@2|Bacteria,1PJTM@1224|Proteobacteria,1SYS3@1236|Gammaproteobacteria,4672R@72275|Alteromonadaceae 1236|Gammaproteobacteria E Peptidase family M1 domain - - 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - ERAP1_C,Peptidase_M1 k141_22383_1 911045.PSE_1423 4.42e-64 212.0 COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2TSB1@28211|Alphaproteobacteria 28211|Alphaproteobacteria EH Belongs to the TPP enzyme family MA20_00650 - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N k141_22383_2 1122134.KB893650_gene23 2.68e-41 144.0 COG1028@1|root,COG1028@2|Bacteria,1MWJI@1224|Proteobacteria,1S2WT@1236|Gammaproteobacteria,1XR57@135619|Oceanospirillales 135619|Oceanospirillales IQ KR domain - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 k141_36676_1 1131730.BAVI_02454 6.21e-116 342.0 COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,4HB0P@91061|Bacilli,1ZQFT@1386|Bacillus 91061|Bacilli L transposase mutator type - - - - - - - - - - - - Transposase_mut k141_28423_2 218284.CCDN010000005_gene3248 1.01e-08 55.5 COG2182@1|root,COG2182@2|Bacteria,1TPU9@1239|Firmicutes,4HBHE@91061|Bacilli,1ZBWG@1386|Bacillus 91061|Bacilli G COG2182 Maltose-binding periplasmic proteins domains cycB - - ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 M00207,M00491,M00599 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.16,3.A.1.1.2,3.A.1.1.38 - - SBP_bac_8 k141_36678_1 218284.CCDN010000001_gene478 5.57e-135 385.0 2DD6N@1|root,2ZGSV@2|Bacteria,1V2G7@1239|Firmicutes,4HGWA@91061|Bacilli,1ZCUK@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_30651_2 1453501.JELR01000001_gene2001 1.74e-168 475.0 COG2084@1|root,COG2084@2|Bacteria,1MUGU@1224|Proteobacteria,1RQ2D@1236|Gammaproteobacteria,464XV@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases garR - 1.1.1.31,1.1.1.60 ko:K00020,ko:K00042 ko00280,ko00630,ko01100,map00280,map00630,map01100 - R01745,R01747,R05066 RC00099 ko00000,ko00001,ko01000 - - - NAD_binding_11,NAD_binding_2 k141_21375_1 272558.10176622 1.71e-29 107.0 COG1694@1|root,COG1694@2|Bacteria,1VA3E@1239|Firmicutes,4HKDQ@91061|Bacilli,1ZI1C@1386|Bacillus 91061|Bacilli S MazG-like family - - - - - - - - - - - - MazG-like k141_28425_1 406124.ACPC01000049_gene170 6.27e-155 442.0 COG2356@1|root,COG4085@1|root,COG2356@2|Bacteria,COG4085@2|Bacteria,1U9GI@1239|Firmicutes,4IJKB@91061|Bacilli,1ZAYK@1386|Bacillus 91061|Bacilli L Ribonuclease bsn GO:0005575,GO:0005576 - - - - - - - - - - Endonuclease_1 k141_37961_1 218284.CCDN010000002_gene2841 1.14e-111 328.0 COG3589@1|root,COG3589@2|Bacteria,1TRIY@1239|Firmicutes,4H9V2@91061|Bacilli,1ZDI0@1386|Bacillus 91061|Bacilli S Bacterial protein of unknown function (DUF871) - - - ko:K09963 - - - - ko00000 - - - DUF871 k141_28427_1 42565.FP66_07140 2.14e-109 316.0 COG5405@1|root,COG5405@2|Bacteria,1MVF2@1224|Proteobacteria,1RP7P@1236|Gammaproteobacteria,1XIAU@135619|Oceanospirillales 135619|Oceanospirillales O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery hslV - 3.4.25.2 ko:K01419 - - - - ko00000,ko01000,ko01002 - - - Proteasome k141_31792_1 265729.GS18_0216500 4.46e-43 143.0 2DJ0G@1|root,32UC2@2|Bacteria,1VCTC@1239|Firmicutes,4HKM5@91061|Bacilli,1ZR82@1386|Bacillus 91061|Bacilli S Heat induced stress protein YflT yflT - - - - - - - - - - - YflT k141_31792_2 218284.CCDN010000002_gene2047 9.26e-85 254.0 COG0406@1|root,COG0406@2|Bacteria,1VBE0@1239|Firmicutes,4HJR9@91061|Bacilli,1ZGF2@1386|Bacillus 91061|Bacilli G Histidine phosphatase superfamily (branch 1) - - - - - - - - - - - - His_Phos_1 k141_31792_3 218284.CCDN010000002_gene2045 1.77e-109 333.0 28HMX@1|root,2Z7WB@2|Bacteria,1TPJG@1239|Firmicutes,4HBRI@91061|Bacilli,1ZCDH@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_37963_1 665959.HMPREF1013_00157 3.51e-57 188.0 COG2855@1|root,COG2855@2|Bacteria,1TQYA@1239|Firmicutes,4HCCP@91061|Bacilli,1ZATM@1386|Bacillus 91061|Bacilli S Conserved hypothetical protein 698 - - - - - - - - - - - - Cons_hypoth698 k141_15343_1 338963.Pcar_1752 8e-53 179.0 COG4962@1|root,COG4962@2|Bacteria,1R7EN@1224|Proteobacteria,42NAK@68525|delta/epsilon subdivisions,2WIYX@28221|Deltaproteobacteria,43SA4@69541|Desulfuromonadales 28221|Deltaproteobacteria U PFAM type II secretion system protein E - - - ko:K02283,ko:K03609 - - - - ko00000,ko02035,ko02044,ko03036,ko04812 - - - CbiA,FHA,T2SSE k141_15343_2 443143.GM18_2434 2.64e-63 210.0 COG4965@1|root,COG4965@2|Bacteria,1MUXK@1224|Proteobacteria,42QS0@68525|delta/epsilon subdivisions,2WMU6@28221|Deltaproteobacteria,43SJM@69541|Desulfuromonadales 28221|Deltaproteobacteria U Type II secretion system (T2SS), protein F - - - ko:K12510 - - - - ko00000,ko02044 - - - T2SSF k141_30802_1 218284.CCDN010000006_gene3524 3.69e-140 399.0 COG1120@1|root,COG1120@2|Bacteria,1TP2Q@1239|Firmicutes,4HADG@91061|Bacilli,1ZBMI@1386|Bacillus 91061|Bacilli HP ABC transporter yusV - 3.6.3.34 ko:K02013 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 - - ABC_tran k141_36783_2 1042377.AFPJ01000028_gene2306 1.53e-105 324.0 COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,1RMMQ@1236|Gammaproteobacteria,46544@72275|Alteromonadaceae 1236|Gammaproteobacteria L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) recG GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecG_wedge k141_15433_1 218284.CCDN010000002_gene2230 5.61e-122 361.0 COG0654@1|root,COG0654@2|Bacteria,1U29G@1239|Firmicutes,4HF0P@91061|Bacilli,1ZE9I@1386|Bacillus 91061|Bacilli CH FAD binding domain - - - - - - - - - - - - FAD_binding_3 k141_36784_2 218284.CCDN010000001_gene1617 8.8e-43 143.0 COG1670@1|root,COG1670@2|Bacteria,1V576@1239|Firmicutes,4HH3E@91061|Bacilli,1ZRE3@1386|Bacillus 91061|Bacilli J Acetyltransferase (GNAT) domain - - 2.3.1.128 ko:K03790 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 k141_36785_1 1298593.TOL_0879 1.49e-48 167.0 COG1524@1|root,COG1524@2|Bacteria,1PR75@1224|Proteobacteria,1RZUP@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Type I phosphodiesterase / nucleotide pyrophosphatase - - - - - - - - - - - - Phosphodiest k141_15434_1 218284.CCDN010000001_gene1164 2.68e-185 532.0 COG1199@1|root,COG1199@2|Bacteria,1TRNV@1239|Firmicutes,4HBYD@91061|Bacilli,1ZARY@1386|Bacillus 91061|Bacilli KL COG1199 Rad3-related DNA helicases ypvA - 3.6.4.12 ko:K03722 - - - - ko00000,ko01000,ko03400 - - - Helicase_C_2 k141_36787_1 218284.CCDN010000001_gene629 7e-165 463.0 COG2894@1|root,COG2894@2|Bacteria,1TP6P@1239|Firmicutes,4HB2F@91061|Bacilli,1ZB5P@1386|Bacillus 91061|Bacilli D Belongs to the ParA family minD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03609 - - - - ko00000,ko03036,ko04812 - - - AAA_31,CbiA k141_15435_1 1294265.JCM21738_915 9.17e-65 198.0 29V5T@1|root,30GJF@2|Bacteria,1UA39@1239|Firmicutes,4IKCT@91061|Bacilli,1ZGGQ@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_30805_1 218284.CCDN010000005_gene3195 3.77e-208 590.0 COG1388@1|root,COG3858@1|root,COG1388@2|Bacteria,COG3858@2|Bacteria,1TQK2@1239|Firmicutes,4HBJC@91061|Bacilli,1ZBQC@1386|Bacillus 91061|Bacilli M Glycoside Hydrolase Family yaaH_2 - - ko:K06306 - - - - ko00000 - - - Glyco_hydro_18,LysM k141_30805_2 1499685.CCFJ01000057_gene436 1.34e-11 62.4 COG1309@1|root,COG1309@2|Bacteria,1V2H2@1239|Firmicutes,4HHJD@91061|Bacilli,1ZFYK@1386|Bacillus 91061|Bacilli K Transcriptional regulator yhgD - - ko:K09017 - - - - ko00000,ko03000 - - - TetR_N k141_36790_1 1121938.AUDY01000013_gene3177 3.05e-76 246.0 COG1620@1|root,COG1620@2|Bacteria,1TQNM@1239|Firmicutes,4HAF3@91061|Bacilli,3NFNB@45667|Halobacillus 91061|Bacilli C L-lactate permease - - - ko:K03303 - - - - ko00000,ko02000 2.A.14 - - Lactate_perm k141_36792_1 1196031.ALEG01000011_gene5227 1.03e-36 135.0 COG0398@1|root,COG0398@2|Bacteria,1V7NH@1239|Firmicutes,4HJDU@91061|Bacilli,1ZEF7@1386|Bacillus 91061|Bacilli S SNARE associated Golgi protein yjbF - - - - - - - - - - - SNARE_assoc k141_31915_1 1294265.JCM21738_942 3.31e-77 242.0 COG2603@1|root,COG2603@2|Bacteria,1TQ8T@1239|Firmicutes,4HBX4@91061|Bacilli,1ZCJF@1386|Bacillus 91061|Bacilli S tRNA 2-selenouridine synthase selU - - ko:K06917 - - - - ko00000,ko01000,ko03016 - - - Rhodanese k141_15437_1 1294265.JCM21738_2827 2.78e-128 374.0 COG1301@1|root,COG1301@2|Bacteria,1TPME@1239|Firmicutes,4HB4X@91061|Bacilli,1ZDVI@1386|Bacillus 91061|Bacilli C Sodium:dicarboxylate symporter family - - - - - - - - - - - - SDF k141_30807_1 218284.CCDN010000001_gene653 5.34e-76 236.0 COG0343@1|root,COG0343@2|Bacteria,1TNZ4@1239|Firmicutes,4HCNM@91061|Bacilli,1ZBFJ@1386|Bacillus 91061|Bacilli F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) tgt GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 ko:K00773 - - R03789,R10209 RC00063 ko00000,ko01000,ko03016 - - - TGT k141_30807_2 218284.CCDN010000001_gene654 1.75e-46 150.0 COG1862@1|root,COG1862@2|Bacteria,1VEMC@1239|Firmicutes,4HNK0@91061|Bacilli,1ZHST@1386|Bacillus 91061|Bacilli U Preprotein translocase subunit YajC yajC - - ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - YajC k141_31916_1 218284.CCDN010000001_gene1510 5.32e-22 97.4 COG1921@1|root,COG1921@2|Bacteria,1TQT8@1239|Firmicutes,4HAAC@91061|Bacilli,1ZCFY@1386|Bacillus 91061|Bacilli E Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis selA - 2.9.1.1 ko:K01042 ko00450,ko00970,map00450,map00970 - R08219 RC01246 ko00000,ko00001,ko01000 - - - Se-cys_synth_N,SelA k141_36793_2 1187848.AJYQ01000099_gene2387 2.25e-126 379.0 COG0582@1|root,COG0582@2|Bacteria,1REKP@1224|Proteobacteria,1T01S@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_integrase k141_31918_2 1453501.JELR01000002_gene852 9.88e-98 297.0 COG2721@1|root,COG2721@2|Bacteria,1MU9V@1224|Proteobacteria,1RP0M@1236|Gammaproteobacteria,4664Y@72275|Alteromonadaceae 1236|Gammaproteobacteria G COG2721 Altronate dehydratase - - 4.2.1.7 ko:K01685 ko00040,ko01100,map00040,map01100 M00631 R01540 RC00543 ko00000,ko00001,ko00002,ko01000 - - - GD_AH_C,SAF k141_15440_1 218284.CCDN010000001_gene1485 2.14e-48 166.0 COG1372@1|root,COG1372@2|Bacteria,1VPYF@1239|Firmicutes,4HSTN@91061|Bacilli,1ZEPN@1386|Bacillus 91061|Bacilli L LAGLIDADG-like domain - - - - - - - - - - - - LAGLIDADG_3 k141_30810_1 1122197.ATWI01000012_gene578 2.58e-80 246.0 COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,1RS6U@1236|Gammaproteobacteria,4648K@72275|Alteromonadaceae 1236|Gammaproteobacteria K Transcriptional regulator IV02_27905 - - - - - - - - - - - HTH_1,LysR_substrate k141_30810_2 1517416.IDAT_12530 1.4e-89 272.0 COG1062@1|root,COG1062@2|Bacteria,1MUK4@1224|Proteobacteria,1RNQ4@1236|Gammaproteobacteria,2QFCB@267893|Idiomarinaceae 1236|Gammaproteobacteria C Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily adhC - 1.1.1.1,1.1.1.284 ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 - R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N k141_31919_1 42565.FP66_08400 1.69e-76 233.0 COG3143@1|root,COG3143@2|Bacteria,1NIV6@1224|Proteobacteria,1RNG2@1236|Gammaproteobacteria,1XJNC@135619|Oceanospirillales 135619|Oceanospirillales NT Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) cheZ - - ko:K03414 ko02030,map02030 - - - ko00000,ko00001,ko02035 - - - CheZ k141_31919_2 42565.FP66_08405 6.21e-40 143.0 COG1377@1|root,COG1377@2|Bacteria,1MUWI@1224|Proteobacteria,1RMHA@1236|Gammaproteobacteria,1XH8G@135619|Oceanospirillales 135619|Oceanospirillales N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin flhB - - ko:K02401 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - Bac_export_2 k141_36797_1 218284.CCDN010000001_gene1950 1.85e-54 180.0 COG2334@1|root,COG2334@2|Bacteria,1TSRC@1239|Firmicutes,4HEJ3@91061|Bacilli,1ZEJM@1386|Bacillus 91061|Bacilli S homoserine kinase type II (protein kinase fold) yerI - - - - - - - - - - - APH k141_15442_1 997346.HMPREF9374_0342 1.4e-79 253.0 COG1884@1|root,COG1884@2|Bacteria,1TQAD@1239|Firmicutes,4H9QB@91061|Bacilli,27B33@186824|Thermoactinomycetaceae 91061|Bacilli I Methylmalonyl-CoA mutase - - 5.4.99.2 ko:K01848 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00375,M00376,M00741 R00833 RC00395 ko00000,ko00001,ko00002,ko01000 - - - MM_CoA_mutase k141_31920_1 218284.CCDN010000006_gene3744 2.67e-145 418.0 COG1653@1|root,COG1653@2|Bacteria,1U4H4@1239|Firmicutes,4HBJP@91061|Bacilli,1ZCZR@1386|Bacillus 91061|Bacilli G Bacterial extracellular solute-binding protein malE - - ko:K02027 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - SBP_bac_1,SBP_bac_8 k141_31921_2 408672.NBCG_04998 3.84e-09 60.8 COG3639@1|root,COG3639@2|Bacteria,2IAPI@201174|Actinobacteria,4DRXU@85009|Propionibacteriales 201174|Actinobacteria P Binding-protein-dependent transport system inner membrane component - - - ko:K02042 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - BPD_transp_1 k141_36799_1 1453501.JELR01000002_gene428 8.48e-96 295.0 COG4264@1|root,COG4264@2|Bacteria,1NEZU@1224|Proteobacteria,1RN4A@1236|Gammaproteobacteria,469KE@72275|Alteromonadaceae 1236|Gammaproteobacteria Q IucA / IucC family - - - - - - - - - - - - FhuF,IucA_IucC k141_36799_2 1453501.JELR01000002_gene429 7.67e-23 95.5 COG0477@1|root,COG0477@2|Bacteria,1R8RW@1224|Proteobacteria,1SYEU@1236|Gammaproteobacteria,46ASG@72275|Alteromonadaceae 1236|Gammaproteobacteria EGP Major Facilitator Superfamily yceE - - - - - - - - - - - MFS_1,Sugar_tr k141_31922_1 218284.CCDN010000001_gene776 3.57e-68 208.0 COG4446@1|root,COG4446@2|Bacteria,1U9KE@1239|Firmicutes,4IJRW@91061|Bacilli,1ZJ6Q@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF1499) - - - - - - - - - - - - DUF1499 k141_15443_1 218284.CCDN010000005_gene3176 2.3e-48 159.0 COG1846@1|root,COG1846@2|Bacteria,1UY04@1239|Firmicutes,4HBQS@91061|Bacilli,1ZBRK@1386|Bacillus 91061|Bacilli K Negative regulator of protease production and sporulation hpr GO:0000003,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - ko:K09682 - - - - ko00000,ko03000 - - - MarR k141_15443_2 218284.CCDN010000005_gene3175 5.7e-62 191.0 2D8K4@1|root,32TRG@2|Bacteria,1VCG9@1239|Firmicutes,4HMCV@91061|Bacilli,1ZJ2C@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF1878) yhaI - - - - - - - - - - - DUF1878 k141_15443_3 218284.CCDN010000005_gene3174 6.38e-123 350.0 293PD@1|root,2ZR52@2|Bacteria,1V3PX@1239|Firmicutes,4HI32@91061|Bacilli,1ZFA0@1386|Bacillus 91061|Bacilli S Putative zincin peptidase yhaK - - - - - - - - - - - DUF3267 k141_36801_1 938293.CAJU020000026_gene612 5.3e-08 59.7 COG1136@1|root,COG1136@2|Bacteria,1V3HH@1239|Firmicutes,24CJ4@186801|Clostridia,22IU1@1570339|Peptoniphilaceae 186801|Clostridia V ATPases associated with a variety of cellular activities pstB1 - - ko:K02068 - M00211 - - ko00000,ko00002,ko02000 - - - ABC_tran k141_36801_2 1279017.AQYJ01000027_gene1658 3.78e-68 213.0 COG4149@1|root,COG4149@2|Bacteria,1MUXR@1224|Proteobacteria,1RRDV@1236|Gammaproteobacteria,465C4@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG4149 ABC-type molybdate transport system, permease component modB - - ko:K02018 ko02010,map02010 M00189 - - ko00000,ko00001,ko00002,ko02000 3.A.1.8 - - BPD_transp_1 k141_31924_1 714961.BFZC1_16200 1.91e-26 112.0 COG0420@1|root,COG0420@2|Bacteria,1TWMI@1239|Firmicutes,4HCA0@91061|Bacilli,3IXEX@400634|Lysinibacillus 91061|Bacilli L Calcineurin-like phosphoesterase yhaO - - ko:K03547 - - - - ko00000,ko03400 - - - Metallophos,Metallophos_2 k141_15444_1 1177154.Y5S_01706 5.88e-84 282.0 COG1361@1|root,COG1361@2|Bacteria,1QVSF@1224|Proteobacteria 1224|Proteobacteria M domain protein - - - - - - - - - - - - CARDB,DUF11,OmpA_membrane k141_36803_1 1034347.CAHJ01000062_gene975 4.46e-99 301.0 COG0277@1|root,COG0277@2|Bacteria,1TPBC@1239|Firmicutes,4H9UU@91061|Bacilli,1ZCHD@1386|Bacillus 91061|Bacilli C FAD linked oxidases, C-terminal domain glcD - 1.1.3.15 ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001,ko01000 - - - FAD-oxidase_C,FAD_binding_4 k141_30812_1 29495.EA26_17145 1.38e-61 189.0 COG4519@1|root,COG4519@2|Bacteria,1N38K@1224|Proteobacteria,1SAIP@1236|Gammaproteobacteria,1XXSB@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria - - - - - - - - - - - - HTH_43 k141_30812_2 1116375.VEJY3_11670 3.18e-75 225.0 COG1393@1|root,COG1393@2|Bacteria,1MZ6S@1224|Proteobacteria,1S8TR@1236|Gammaproteobacteria,1XXZI@135623|Vibrionales 135623|Vibrionales P Belongs to the ArsC family yffB - - - - - - - - - - - ArsC k141_30812_3 1116375.VEJY3_11675 3.21e-266 729.0 COG0624@1|root,COG0624@2|Bacteria,1MW6G@1224|Proteobacteria,1RMNQ@1236|Gammaproteobacteria,1XTY6@135623|Vibrionales 135623|Vibrionales E Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls dapE GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009014,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20 k141_30812_4 1116375.VEJY3_11680 2.58e-140 399.0 COG1876@1|root,COG1876@2|Bacteria,1N2IC@1224|Proteobacteria,1S0DU@1236|Gammaproteobacteria,1XTV4@135623|Vibrionales 135623|Vibrionales M COG1876 D-alanyl-D-alanine carboxypeptidase - - - - - - - - - - - - VanY k141_15445_1 218284.CCDN010000008_gene4070 5.84e-107 321.0 COG2244@1|root,COG2244@2|Bacteria,1V929@1239|Firmicutes,4HKDX@91061|Bacilli,1ZF2G@1386|Bacillus 91061|Bacilli S Polysaccharide biosynthesis protein - - - - - - - - - - - - Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C k141_30816_1 329726.AM1_0951 1.7e-63 219.0 COG0474@1|root,COG0474@2|Bacteria,1G0JX@1117|Cyanobacteria 1117|Cyanobacteria P ATPase, P-type (transporting), HAD superfamily, subfamily IC - - 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3 k141_15448_1 218284.CCDN010000002_gene2030 1.73e-188 532.0 COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,4HA6M@91061|Bacilli,1ZB9G@1386|Bacillus 91061|Bacilli J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family rlmCD GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070041,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.190 ko:K03215 - - - - ko00000,ko01000,ko03009 - - - TRAM,tRNA_U5-meth_tr k141_30817_1 443152.MDG893_15387 3.27e-46 169.0 COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,1RQPW@1236|Gammaproteobacteria,469ZW@72275|Alteromonadaceae 1236|Gammaproteobacteria S Tripartite tricarboxylate transporter TctA family - - - - - - - - - - - - TctA k141_30818_1 665959.HMPREF1013_00002 5.11e-22 92.8 2CDA7@1|root,3090E@2|Bacteria,1U48U@1239|Firmicutes,4IMA4@91061|Bacilli,1ZJKS@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_36805_1 1283300.ATXB01000001_gene1705 1.55e-170 493.0 COG1387@1|root,COG1387@2|Bacteria,1MYXV@1224|Proteobacteria,1SZW9@1236|Gammaproteobacteria,1XFPE@135618|Methylococcales 135618|Methylococcales L DNA polymerase X family - - - ko:K02347 - - - - ko00000,ko03400 - - - DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8,PHP k141_36805_2 411154.GFO_3213 8.82e-51 175.0 COG0266@1|root,COG0266@2|Bacteria,4NFM2@976|Bacteroidetes,1HYNY@117743|Flavobacteriia 976|Bacteroidetes L Formamidopyrimidine-DNA glycosylase N-terminal domain mutM - 3.2.2.23,4.2.99.18 ko:K10563 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Fapy_DNA_glyco,H2TH,zf-FPG_IleRS k141_36805_3 1283300.ATXB01000002_gene2668 1.01e-245 691.0 COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,1RME8@1236|Gammaproteobacteria,1XE3D@135618|Methylococcales 1236|Gammaproteobacteria O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins - - - ko:K03798 - M00742 - - ko00000,ko00002,ko01000,ko01002,ko03110 - - - AAA,FtsH_ext,Peptidase_M41 k141_30820_2 279010.BL00983 2.6e-121 363.0 2DB9U@1|root,2Z7Z6@2|Bacteria,1TR67@1239|Firmicutes,4HCTZ@91061|Bacilli,1ZEZR@1386|Bacillus 91061|Bacilli S Phage portal protein, SPP1 Gp6-like - - - - - - - - - - - - Phage_prot_Gp6 k141_31934_1 218284.CCDN010000001_gene64 2.35e-212 587.0 COG0564@1|root,COG0564@2|Bacteria,1TPCM@1239|Firmicutes,4HBG2@91061|Bacilli,1ZC3M@1386|Bacillus 91061|Bacilli J Responsible for synthesis of pseudouridine from uracil rluD GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 ko:K06180 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 k141_30822_1 95619.PM1_0207950 4.14e-57 200.0 COG2206@1|root,COG3437@1|root,COG2206@2|Bacteria,COG3437@2|Bacteria,1MV37@1224|Proteobacteria,1RM9C@1236|Gammaproteobacteria 1236|Gammaproteobacteria T COG0840 Methyl-accepting chemotaxis protein - - - - - - - - - - - - GAF_3,HD_5,dCache_1 k141_15452_2 218284.CCDN010000001_gene1208 1.01e-132 384.0 COG1162@1|root,COG1162@2|Bacteria,1TP8Q@1239|Firmicutes,4H9PJ@91061|Bacilli,1ZCAI@1386|Bacillus 91061|Bacilli S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit rsgA_2 - 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 - R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 - - - RsgA_GTPase k141_31937_1 1396141.BATP01000042_gene1896 1.09e-71 231.0 COG0845@1|root,COG0845@2|Bacteria,46UZZ@74201|Verrucomicrobia,2IVAY@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Biotin-lipoyl like - - - - - - - - - - - - HlyD_D23 k141_36809_1 1121929.KB898662_gene341 4.38e-82 259.0 COG1215@1|root,COG1215@2|Bacteria,1TR2P@1239|Firmicutes,4HAQN@91061|Bacilli,471CS@74385|Gracilibacillus 91061|Bacilli M COG1215 Glycosyltransferases, probably involved in cell wall biogenesis ica2 - - - - - - - - - - - Glyco_tranf_2_3,Glycos_transf_2 k141_15453_2 223926.28808888 4.61e-53 170.0 2AWCX@1|root,31N8S@2|Bacteria,1QK02@1224|Proteobacteria,1TI2G@1236|Gammaproteobacteria,1XY85@135623|Vibrionales 135623|Vibrionales - - VPA0654 - - - - - - - - - - - - k141_8324_1 42565.FP66_03200 1.1e-102 316.0 COG1292@1|root,COG1292@2|Bacteria,1MV0K@1224|Proteobacteria,1RP3E@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Belongs to the BCCT transporter (TC 2.A.15) family betT GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033554,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051716,GO:0071944 - ko:K02168 - - - - ko00000,ko02000 2.A.15.1.3,2.A.15.1.4 - iAF1260.b0314,iB21_1397.B21_00273,iEC042_1314.EC042_0347,iEC55989_1330.EC55989_0316,iECBD_1354.ECBD_3344,iECB_1328.ECB_00270,iECDH10B_1368.ECDH10B_0301,iECD_1391.ECD_00270,iECH74115_1262.ECH74115_0376,iECIAI1_1343.ECIAI1_0311,iECO103_1326.ECO103_0291,iECO111_1330.ECO111_0348,iECO26_1355.ECO26_0348,iECSE_1348.ECSE_0335,iECSP_1301.ECSP_0369,iECUMN_1333.ECUMN_0352,iECW_1372.ECW_m0388,iECs_1301.ECs0360,iEKO11_1354.EKO11_3531,iEcDH1_1363.EcDH1_3292,iEcE24377_1341.EcE24377A_0331,iEcHS_1320.EcHS_A0373,iEcolC_1368.EcolC_3309,iG2583_1286.G2583_0418,iJO1366.b0314,iJR904.b0314,iUMNK88_1353.UMNK88_361,iWFL_1372.ECW_m0388,iY75_1357.Y75_RS01625,iZ_1308.Z0401 BCCT k141_23780_1 1410674.JNKU01000006_gene1654 9.19e-12 70.5 COG0463@1|root,COG0463@2|Bacteria,1VVRP@1239|Firmicutes,4HVYS@91061|Bacilli,3FBY0@33958|Lactobacillaceae 91061|Bacilli M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 k141_2378_1 1042377.AFPJ01000052_gene1582 7.05e-89 287.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria,4651V@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec k141_14268_1 1122194.AUHU01000002_gene2440 6.46e-13 68.9 COG1506@1|root,COG1506@2|Bacteria,1MUJ3@1224|Proteobacteria,1RRN4@1236|Gammaproteobacteria,465BC@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases pqqM - - - - - - - - - - - PD40,Peptidase_S9 k141_5946_2 1463821.JOGR01000008_gene2037 1.37e-07 55.1 COG1846@1|root,COG1846@2|Bacteria,2GJ6W@201174|Actinobacteria 201174|Actinobacteria K MarR family - - - - - - - - - - - - MarR_2 k141_26158_1 221109.22776413 6.67e-90 288.0 COG1404@1|root,COG1404@2|Bacteria,1TPH1@1239|Firmicutes,4HBQH@91061|Bacilli,23IZR@182709|Oceanobacillus 91061|Bacilli O PA domain prtS - 3.4.21.110,3.4.21.96 ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 - - - ko00000,ko00001,ko01000,ko01002,ko03110 - - - FIVAR,Gram_pos_anchor,Inhibitor_I9,PA,Peptidase_S8,SLH,YSIRK_signal,fn3_5 k141_27347_1 469616.FMAG_01961 2.42e-26 107.0 COG1783@1|root,COG1783@2|Bacteria,3797J@32066|Fusobacteria 32066|Fusobacteria S Phage terminase, large subunit, PBSX family - - - ko:K06909 - - - - ko00000 - - - Terminase_3,Terminase_3C k141_27347_2 1307436.PBF_04335 2.22e-37 139.0 2DB9U@1|root,2Z7Z6@2|Bacteria,1TR67@1239|Firmicutes,4HCTZ@91061|Bacilli,1ZEZR@1386|Bacillus 91061|Bacilli S Phage portal protein, SPP1 Gp6-like - - - - - - - - - - - - Phage_prot_Gp6 k141_33292_1 1294265.JCM21738_307 2.12e-50 171.0 COG1749@1|root,COG1749@2|Bacteria,1UHS7@1239|Firmicutes,4IS7Y@91061|Bacilli,1ZS24@1386|Bacillus 91061|Bacilli N flagellar flgE - - ko:K02390 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FlaE,Flg_bb_rod,Flg_bbr_C k141_32222_5 223926.28805582 6.06e-291 794.0 COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,1RNCD@1236|Gammaproteobacteria,1XSAE@135623|Vibrionales 135623|Vibrionales H Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins iscS GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - - Aminotran_5 k141_32222_6 1280001.BAOA01000163_gene2083 1.93e-110 318.0 COG1959@1|root,COG1959@2|Bacteria,1RDA4@1224|Proteobacteria,1S3RW@1236|Gammaproteobacteria,1XTCH@135623|Vibrionales 135623|Vibrionales K Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins iscR - - ko:K13643 - - - - ko00000,ko03000 - - - Rrf2 k141_32222_7 1116375.VEJY3_02715 4.74e-155 437.0 COG0565@1|root,COG0565@2|Bacteria,1N47Y@1224|Proteobacteria,1RPD3@1236|Gammaproteobacteria,1XSWM@135623|Vibrionales 135623|Vibrionales J Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA trmJ - 2.1.1.200 ko:K15396 - - - - ko00000,ko01000,ko03016 - - - SpoU_methylase k141_32222_8 223926.28805579 5.89e-188 522.0 COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,1RNME@1236|Gammaproteobacteria,1XSBJ@135623|Vibrionales 135623|Vibrionales G COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family suhB GO:0003674,GO:0003824,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 - - - Inositol_P k141_32222_9 1219076.N646_2750 1.5e-49 161.0 2A42B@1|root,30SM4@2|Bacteria,1PBVA@1224|Proteobacteria,1TITN@1236|Gammaproteobacteria,1XZMT@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_32222_10 1219076.N646_2749 2.32e-83 247.0 2AWPR@1|root,31NKN@2|Bacteria,1QKBC@1224|Proteobacteria,1TIEU@1236|Gammaproteobacteria,1XZ07@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_32222_11 223926.28805577 2.69e-172 484.0 COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,1RNTY@1236|Gammaproteobacteria,1XTB0@135623|Vibrionales 135623|Vibrionales U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secF - - ko:K03074 ko03060,ko03070,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD_SecF,Sec_GG k141_280_1 1033734.CAET01000076_gene3069 7.53e-55 179.0 COG1352@1|root,COG1352@2|Bacteria,1TPD8@1239|Firmicutes,4HAS1@91061|Bacilli,1ZCKU@1386|Bacillus 91061|Bacilli NT COG1352 Methylase of chemotaxis methyl-accepting proteins cheR - 2.1.1.80 ko:K00575 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko01000,ko02035 - - - CheR,CheR_N k141_22774_1 1294265.JCM21738_2815 6.84e-57 184.0 COG2321@1|root,COG2321@2|Bacteria,1TQKF@1239|Firmicutes,4HB7I@91061|Bacilli,1ZCSY@1386|Bacillus 91061|Bacilli S Putative neutral zinc metallopeptidase XK27_03670 - - ko:K07054 - - - - ko00000 - - - Zn_peptidase k141_12101_2 218284.CCDN010000001_gene1124 2.74e-100 292.0 COG0723@1|root,COG0723@2|Bacteria,1TQUH@1239|Firmicutes,4HBX1@91061|Bacilli,1ZFNX@1386|Bacillus 91061|Bacilli C Menaquinol-cytochrome c reductase qcrA - - ko:K03886 ko00190,ko01100,map00190,map01100 M00151 - - ko00000,ko00001,ko00002,ko01000 - - - CytB6-F_Fe-S,Rieske k141_4925_1 926550.CLDAP_08020 2.4e-54 183.0 COG3534@1|root,COG3534@2|Bacteria,2G8IC@200795|Chloroflexi 200795|Chloroflexi G Glycosyl hydrolase catalytic core - - - - - - - - - - - - Glyco_hydro_cc k141_26407_1 1385511.N783_09995 2.34e-63 206.0 COG2223@1|root,COG2223@2|Bacteria,1TRS9@1239|Firmicutes,4HEBM@91061|Bacilli,2YBE2@289201|Pontibacillus 91061|Bacilli P Involved in the transport of nitrate and nitrite narK - - ko:K02575 ko00910,map00910 M00615 - - ko00000,ko00001,ko00002,ko02000 2.A.1.8 - - MFS_1 k141_35812_1 218284.CCDN010000001_gene427 3.4e-124 362.0 2C0SV@1|root,33X5Q@2|Bacteria,1VW58@1239|Firmicutes,4HWC1@91061|Bacilli 91061|Bacilli S Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10 k141_16823_1 1042377.AFPJ01000030_gene438 5e-216 606.0 COG0154@1|root,COG0154@2|Bacteria,1MW3Z@1224|Proteobacteria,1RP33@1236|Gammaproteobacteria,464XC@72275|Alteromonadaceae 1236|Gammaproteobacteria J Amidase - - 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Amidase k141_16823_2 203122.Sde_1072 1.5e-07 52.8 2E3UE@1|root,32YRS@2|Bacteria,1N75A@1224|Proteobacteria,1S9W5@1236|Gammaproteobacteria,468Q7@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF2799) - - - - - - - - - - - - DUF2799 k141_6230_1 218284.CCDN010000007_gene3946 4.05e-92 289.0 COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H9SA@91061|Bacilli,1ZBUK@1386|Bacillus 91061|Bacilli M penicillin-binding protein pbpG GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.4.1.129,3.4.16.4 ko:K21464 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase k141_3801_1 1279017.AQYJ01000023_gene3241 2.01e-56 189.0 COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,1RMDI@1236|Gammaproteobacteria,4650C@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG0348 Polyferredoxin ccoG - - - - - - - - - - - Fer4_18,Fer4_5,FixG_C k141_3801_2 1279017.AQYJ01000023_gene3242 8.37e-75 229.0 COG3198@1|root,COG3198@2|Bacteria,1N75J@1224|Proteobacteria,1SC87@1236|Gammaproteobacteria,468BX@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria ccoH - - ko:K09926 - - - - ko00000 - - - FixH k141_3801_3 1279017.AQYJ01000023_gene3243 0.0 1186.0 COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,464SF@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG2217 Cation transport ATPase ccoI - 3.6.3.4 ko:K01533 - - R00086 RC00002 ko00000,ko01000 3.A.3.5 - - ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase k141_3801_4 1279017.AQYJ01000023_gene3244 6.04e-19 80.1 COG3197@1|root,COG3197@2|Bacteria,1NG90@1224|Proteobacteria,1SGQG@1236|Gammaproteobacteria,46912@72275|Alteromonadaceae 1236|Gammaproteobacteria P protein, possibly involved in nitrogen fixation ccoS - - - - - - - - - - - FixS k141_3801_5 1279017.AQYJ01000023_gene3245 1.3e-100 300.0 COG2836@1|root,COG2836@2|Bacteria,1RIGJ@1224|Proteobacteria,1S5V1@1236|Gammaproteobacteria,466TY@72275|Alteromonadaceae 1236|Gammaproteobacteria S Cytochrome C biogenesis protein transmembrane region braZ - - ko:K09792 - - - - ko00000 - - - DsbD_2 k141_3801_7 1121413.JMKT01000009_gene1935 9.71e-19 81.3 2DNS2@1|root,32YVY@2|Bacteria,1N9QQ@1224|Proteobacteria,42X5E@68525|delta/epsilon subdivisions,2X2FX@28221|Deltaproteobacteria,2MDGG@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k141_3801_8 1279017.AQYJ01000023_gene3246 6.74e-159 450.0 COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,1RMBU@1236|Gammaproteobacteria,465GA@72275|Alteromonadaceae 1236|Gammaproteobacteria H Belongs to the NadC ModD family nadC GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034213,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605 2.4.2.19 ko:K00767 ko00760,ko01100,map00760,map01100 M00115 R03348 RC02877 ko00000,ko00001,ko00002,ko01000 - - iECP_1309.ECP_0109 QRPTase_C,QRPTase_N k141_3801_9 1279017.AQYJ01000023_gene3247 1.5e-88 288.0 COG4223@1|root,COG4223@2|Bacteria,1N10X@1224|Proteobacteria,1RYCQ@1236|Gammaproteobacteria,46D2D@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF1631) - - - - - - - - - - - - DUF1631 k141_12102_1 218284.CCDN010000007_gene3824 1.6e-12 68.6 COG0739@1|root,COG0739@2|Bacteria,1TRWJ@1239|Firmicutes,4HB43@91061|Bacilli,1ZBXH@1386|Bacillus 91061|Bacilli M G5 nlpD - - - - - - - - - - - G5,LysM,Peptidase_M23 k141_31143_1 926550.CLDAP_28240 9e-122 350.0 COG0235@1|root,COG0235@2|Bacteria,2G63H@200795|Chloroflexi 200795|Chloroflexi G Class II Aldolase and Adducin N-terminal domain - - 5.1.3.4 ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 M00550 R05850 RC01479 ko00000,ko00001,ko00002,ko01000 - - - Aldolase_II k141_31143_2 1449063.JMLS01000004_gene2748 6.46e-23 98.2 COG1069@1|root,COG1069@2|Bacteria,1TP8T@1239|Firmicutes,4HC3A@91061|Bacilli,26TUS@186822|Paenibacillaceae 91061|Bacilli G Belongs to the ribulokinase family araB - 2.7.1.16 ko:K00853 ko00040,ko01100,map00040,map01100 - R01526,R02439 RC00002,RC00538 ko00000,ko00001,ko01000 - - - FGGY_C,FGGY_N k141_7347_1 997296.PB1_06772 4.41e-85 266.0 COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,4HAKH@91061|Bacilli,1ZAWK@1386|Bacillus 91061|Bacilli J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) gltX GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0009986,GO:0030246,GO:0030247,GO:0044464,GO:2001065 6.1.1.24 ko:K09698 ko00970,ko01100,map00970,map01100 M00360 R03651,R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iSB619.SA_RS02860 tRNA-synt_1c k141_37003_1 1209072.ALBT01000023_gene4123 2.11e-05 45.8 COG3940@1|root,COG3940@2|Bacteria,1NKF0@1224|Proteobacteria,1RNIH@1236|Gammaproteobacteria,1FG9G@10|Cellvibrio 1236|Gammaproteobacteria G Glycosyl hydrolases family 43 abf2 - - - - - - - - - - - Glyco_hydro_43 k141_37003_2 498211.CJA_3013 9.08e-97 295.0 COG2211@1|root,COG2211@2|Bacteria,1MVUM@1224|Proteobacteria,1RP5J@1236|Gammaproteobacteria,1FGXW@10|Cellvibrio 1236|Gammaproteobacteria G MFS/sugar transport protein - - - ko:K03292 - - - - ko00000 2.A.2 - - MFS_2 k141_13299_1 42565.FP66_13780 2.58e-30 109.0 COG0818@1|root,COG0818@2|Bacteria,1MZ3Q@1224|Proteobacteria,1S92I@1236|Gammaproteobacteria,1XKEP@135619|Oceanospirillales 135619|Oceanospirillales M Recycling of diacylglycerol produced during the turnover of membrane phospholipid dgkA - 2.7.1.107 ko:K00901 ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231 - R02240 RC00002,RC00017 ko00000,ko00001,ko01000 - - - DAGK_prokar k141_13299_2 42565.FP66_13785 7.5e-63 213.0 COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,1RP9N@1236|Gammaproteobacteria,1XHKJ@135619|Oceanospirillales 135619|Oceanospirillales OT Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell glnE - 2.7.7.42,2.7.7.89 ko:K00982 - - - - ko00000,ko01000 - - - GlnD_UR_UTase,GlnE k141_8537_4 1279017.AQYJ01000020_gene1321 1.7e-120 359.0 COG2114@1|root,COG2114@2|Bacteria,1N41U@1224|Proteobacteria,1SB9D@1236|Gammaproteobacteria,469AN@72275|Alteromonadaceae 1236|Gammaproteobacteria T Pfam Adenylate and Guanylate cyclase catalytic domain - - - - - - - - - - - - - k141_8537_5 1279017.AQYJ01000020_gene1322 3.5e-149 433.0 COG0560@1|root,COG0560@2|Bacteria,1MWA3@1224|Proteobacteria,1RNJE@1236|Gammaproteobacteria,4647E@72275|Alteromonadaceae 1236|Gammaproteobacteria E phosphoserine phosphatase serB GO:0000287,GO:0001505,GO:0003674,GO:0003824,GO:0004647,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006563,GO:0006564,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0017144,GO:0019752,GO:0042133,GO:0042136,GO:0042578,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046872,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.3 ko:K01079 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R00582 RC00017 ko00000,ko00001,ko00002,ko01000,ko01009 - - iE2348C_1286.E2348C_4686,iEC042_1314.EC042_4885,iECO26_1355.ECO26_5594,iECSF_1327.ECSF_4321,iECUMN_1333.ECUMN_5012,iETEC_1333.ETEC_4743,iPC815.YPO0442,iUMNK88_1353.UMNK88_5307 ACT_6,HAD,Hydrolase k141_8537_6 1453501.JELR01000002_gene1392 0.0 1636.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,4648N@72275|Alteromonadaceae 1236|Gammaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family acrF - - ko:K18138 ko01501,ko01503,map01501,map01503 M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2 - - ACR_tran k141_8537_7 1042377.AFPJ01000043_gene833 8.09e-142 412.0 COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,1RQJ9@1236|Gammaproteobacteria,466HH@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K03585 ko01501,ko01503,map01501,map01503 M00646,M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,8.A.1.6 - - HlyD_D23 k141_8537_8 1453501.JELR01000002_gene1394 0.0 1010.0 COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,1RSG9@1236|Gammaproteobacteria,464W2@72275|Alteromonadaceae 1236|Gammaproteobacteria E aminopeptidase pepN - - - - - - - - - - - Leuk-A4-hydro_C,Peptidase_M1 k141_8537_9 1279017.AQYJ01000020_gene1325 0.0 1056.0 COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1PJCA@1224|Proteobacteria,1RS4H@1236|Gammaproteobacteria,4663N@72275|Alteromonadaceae 1236|Gammaproteobacteria T Putative diguanylate phosphodiesterase - - - ko:K21025 ko02025,map02025 - - - ko00000,ko00001 - - - EAL,GGDEF,PAS,PAS_8,PAS_9,Response_reg k141_8537_11 1453501.JELR01000002_gene1397 1.31e-171 488.0 COG1509@1|root,COG1509@2|Bacteria,1MUPJ@1224|Proteobacteria,1RM84@1236|Gammaproteobacteria,4651S@72275|Alteromonadaceae 1236|Gammaproteobacteria C Lysine 2,3-aminomutase YodO family protein epmB GO:0003674,GO:0003824,GO:0005488,GO:0016853,GO:0016866,GO:0016869,GO:0048037,GO:0051536,GO:0051539,GO:0051540 5.4.3.2 ko:K01843,ko:K19810 ko00310,map00310 - R00461 RC00303 ko00000,ko00001,ko01000,ko03012 - - iECH74115_1262.ECH74115_5662,iECIAI39_1322.ECIAI39_4611,iS_1188.S4569 Fer4_12,Fer4_14,Radical_SAM k141_8537_13 1453501.JELR01000002_gene1399 8.13e-168 476.0 COG2269@1|root,COG2269@2|Bacteria,1MU97@1224|Proteobacteria,1RMR9@1236|Gammaproteobacteria,4645R@72275|Alteromonadaceae 1236|Gammaproteobacteria J COG2269 Truncated, possibly inactive, lysyl-tRNA synthetase (class II) epmA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006430,GO:0006464,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016746,GO:0016755,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052868,GO:0071704,GO:0071915,GO:0072580,GO:0072581,GO:0090304,GO:0140096,GO:1901360,GO:1901564,GO:1901566,GO:1901576 - ko:K04568 - - - - ko00000,ko01000,ko03012 - - - tRNA-synt_2 k141_8537_14 1042377.AFPJ01000043_gene840 2.11e-89 273.0 COG0454@1|root,COG0456@2|Bacteria,1NGUX@1224|Proteobacteria,1SV6D@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Acetyltransferase (GNAT) family - - - - - - - - - - - - - k141_8537_15 1042377.AFPJ01000043_gene841 3.68e-149 425.0 COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,1RNCA@1236|Gammaproteobacteria,464X7@72275|Alteromonadaceae 1236|Gammaproteobacteria E Serine acetyltransferase, N-terminal cysE GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009001,GO:0009058,GO:0009069,GO:0009070,GO:0009314,GO:0009333,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016053,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019344,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.3.1.30 ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 M00021 R00586 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,SATase_N k141_8537_16 1279017.AQYJ01000020_gene1333 3.81e-210 583.0 COG2334@1|root,COG2334@2|Bacteria,1MU2Q@1224|Proteobacteria,1RNHI@1236|Gammaproteobacteria,464EM@72275|Alteromonadaceae 1236|Gammaproteobacteria F A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response srkA GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0071704,GO:0140096,GO:1901564 - - - - - - - - - - APH k141_8537_17 1279017.AQYJ01000020_gene1336 1.41e-58 184.0 2D8VC@1|root,32TS1@2|Bacteria,1MZWT@1224|Proteobacteria,1SQ4N@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_8537_18 1279017.AQYJ01000020_gene1337 6.18e-54 172.0 COG0346@1|root,COG0346@2|Bacteria,1RH79@1224|Proteobacteria,1S58S@1236|Gammaproteobacteria 1236|Gammaproteobacteria E PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - - - - - - - - - - Glyoxalase k141_8537_19 95619.PM1_0219750 1.99e-34 127.0 COG1670@1|root,COG1670@2|Bacteria,1RKKE@1224|Proteobacteria,1S47R@1236|Gammaproteobacteria 1236|Gammaproteobacteria J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins - - - ko:K03817 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 k141_6273_1 218284.CCDN010000001_gene1753 5.7e-11 61.6 COG0180@1|root,COG0180@2|Bacteria,1TPY7@1239|Firmicutes,4HE96@91061|Bacilli,1ZE1U@1386|Bacillus 91061|Bacilli J Catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA - - 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1b k141_26435_1 1200792.AKYF01000012_gene984 1.36e-25 110.0 COG0308@1|root,COG0308@2|Bacteria,1U6PC@1239|Firmicutes,4HD74@91061|Bacilli,26R17@186822|Paenibacillaceae 91061|Bacilli E EnpEP protein pepN - - - - - - - - - - - Peptidase_M1 k141_35836_1 298655.KI912267_gene7282 5.09e-31 122.0 COG2041@1|root,COG2041@2|Bacteria,2GMG2@201174|Actinobacteria,4EU92@85013|Frankiales 201174|Actinobacteria S Mo-co oxidoreductase dimerisation domain - - 1.8.3.1 ko:K00387 ko00920,ko01100,ko01120,map00920,map01100,map01120 - R00533 RC00168 ko00000,ko00001,ko01000 - - - Mo-co_dimer,Oxidored_molyb k141_10878_1 631362.Thi970DRAFT_04432 1.35e-154 449.0 COG3263@1|root,COG3263@2|Bacteria,1MVKV@1224|Proteobacteria,1T2D1@1236|Gammaproteobacteria,1X28U@135613|Chromatiales 135613|Chromatiales P Sodium/hydrogen exchanger family - - - ko:K11105 - - - - ko00000,ko02000 2.A.36.6 - - Na_H_Exchanger k141_10878_2 384765.SIAM614_02541 2.14e-23 102.0 COG1289@1|root,COG1289@2|Bacteria 2|Bacteria S transmembrane transporter activity VPA1578 - - - - - - - - - - - FUSC k141_25189_1 42565.FP66_10380 2.61e-27 108.0 COG1292@1|root,COG1292@2|Bacteria,1MV0K@1224|Proteobacteria,1RP3E@1236|Gammaproteobacteria,1XHUS@135619|Oceanospirillales 135619|Oceanospirillales M Belongs to the BCCT transporter (TC 2.A.15) family - - - ko:K03451 - - - - ko00000 2.A.15 - - BCCT k141_25189_2 42565.FP66_10385 1.74e-41 145.0 COG1063@1|root,COG1063@2|Bacteria,1MW6Y@1224|Proteobacteria,1RRPT@1236|Gammaproteobacteria,1XH5A@135619|Oceanospirillales 135619|Oceanospirillales E Alcohol dehydrogenase GroES-like domain fdhA - 1.2.1.46 ko:K00148 ko00625,ko00680,ko01100,ko01120,ko01200,map00625,map00680,map01100,map01120,map01200 - R00604 RC00188 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N k141_33486_1 1294265.JCM21738_4533 2.04e-113 340.0 COG0840@1|root,COG0840@2|Bacteria,1U23G@1239|Firmicutes,4IBKR@91061|Bacilli,1ZMSW@1386|Bacillus 91061|Bacilli NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - - - - - - - - - - MCPsignal k141_1373_1 1274524.BSONL12_04614 8.35e-122 365.0 COG5362@1|root,COG5410@1|root,COG5362@2|Bacteria,COG5410@2|Bacteria,1TSQB@1239|Firmicutes,4HEZU@91061|Bacilli,1ZBBB@1386|Bacillus 91061|Bacilli S TIGRFAM Phage - - - - - - - - - - - - Terminase_6C k141_310_1 223926.28805645 7.85e-61 207.0 COG3156@1|root,COG3156@2|Bacteria,1QJFS@1224|Proteobacteria,1THF6@1236|Gammaproteobacteria,1XV93@135623|Vibrionales 135623|Vibrionales U type II secretion system protein K VP0659 - - - - - - - - - - - - k141_310_2 1280001.BAOA01000038_gene4372 1.76e-52 169.0 COG4967@1|root,COG4967@2|Bacteria,1NI49@1224|Proteobacteria,1SHTN@1236|Gammaproteobacteria,1Y2B5@135623|Vibrionales 135623|Vibrionales NU type IV pilus modification protein PilV - - - ko:K02671 - - - - ko00000,ko02035,ko02044 - - - N_methyl k141_310_3 1280001.BAOA01000038_gene4373 1.21e-206 582.0 COG2978@1|root,COG2978@2|Bacteria,1MUJ1@1224|Proteobacteria,1RMAI@1236|Gammaproteobacteria,1XSAR@135623|Vibrionales 135623|Vibrionales H p-aminobenzoyl-glutamate transporter abgT - - - - - - - - - - - ABG_transport k141_21658_1 1125863.JAFN01000001_gene3399 1.84e-30 125.0 COG0749@1|root,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,42NAV@68525|delta/epsilon subdivisions,2WJ3W@28221|Deltaproteobacteria 28221|Deltaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k141_28798_1 218284.CCDN010000008_gene4150 1.7e-230 641.0 COG1271@1|root,COG1271@2|Bacteria,1TRH4@1239|Firmicutes,4HA19@91061|Bacilli,1ZBAG@1386|Bacillus 91061|Bacilli C oxidase, subunit ythA - 1.10.3.14 ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - Cyt_bd_oxida_I k141_14498_1 1279017.AQYJ01000029_gene3491 5.02e-49 157.0 COG3141@1|root,COG3141@2|Bacteria,1N26M@1224|Proteobacteria,1SCRN@1236|Gammaproteobacteria,468R9@72275|Alteromonadaceae 1236|Gammaproteobacteria S YebG protein - - - ko:K09918 - - - - ko00000 - - - YebG k141_14498_2 1236541.BALL01000036_gene3658 1.64e-44 149.0 COG3788@1|root,COG3788@2|Bacteria,1RDHP@1224|Proteobacteria,1S3PN@1236|Gammaproteobacteria,2QC72@267890|Shewanellaceae 1236|Gammaproteobacteria S MAPEG family - - - ko:K07136 - - - - ko00000 - - - MAPEG k141_14498_3 1279017.AQYJ01000029_gene3489 1.32e-189 540.0 COG1228@1|root,COG1228@2|Bacteria,1MXQX@1224|Proteobacteria,1RQGS@1236|Gammaproteobacteria,465N1@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Amidohydrolase family - - - - - - - - - - - - Amidohydro_1,Amidohydro_3 k141_14498_4 1279017.AQYJ01000029_gene3488 2.65e-274 758.0 COG1228@1|root,COG1228@2|Bacteria,1MXXR@1224|Proteobacteria,1RRK7@1236|Gammaproteobacteria,46458@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Amidohydrolase family - - - - - - - - - - - - Amidohydro_1,Amidohydro_3 k141_14498_5 469595.CSAG_01328 1.6e-05 47.8 COG1396@1|root,COG1396@2|Bacteria,1N0DX@1224|Proteobacteria,1S8KX@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator - - - - - - - - - - - - HTH_3 k141_14498_6 1453501.JELR01000001_gene2104 8.22e-263 735.0 COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RP53@1236|Gammaproteobacteria,466MR@72275|Alteromonadaceae 1236|Gammaproteobacteria T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg k141_14498_8 1042377.AFPJ01000036_gene1155 8.15e-130 377.0 COG1737@1|root,COG1737@2|Bacteria,1ND5W@1224|Proteobacteria,1RNCI@1236|Gammaproteobacteria,4675C@72275|Alteromonadaceae 1236|Gammaproteobacteria K Helix-turn-helix domain, rpiR family yfhH GO:0003674,GO:0003700,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K15835 - - - - ko00000,ko03000 - - - HTH_6,SIS k141_14498_9 1042377.AFPJ01000036_gene1154 6.95e-273 759.0 COG0591@1|root,COG0591@2|Bacteria,1QUXM@1224|Proteobacteria,1T251@1236|Gammaproteobacteria,4653I@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - - - - - - - - - - SSF k141_14498_10 1117647.M5M_07535 1.6e-91 280.0 COG2971@1|root,COG2971@2|Bacteria,1R41I@1224|Proteobacteria,1RPMK@1236|Gammaproteobacteria,1J5VB@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria G BadF BadG BcrA BcrD - - 2.7.1.8 ko:K18676 ko00520,ko01100,map00520,map01100 - R01961 RC00002,RC00017 ko00000,ko00001,ko01000 - - - BcrAD_BadFG k141_14498_11 1042377.AFPJ01000036_gene1152 2.13e-161 459.0 COG2103@1|root,COG2103@2|Bacteria,1MVDR@1224|Proteobacteria,1RN3P@1236|Gammaproteobacteria,465RM@72275|Alteromonadaceae 1236|Gammaproteobacteria G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling murQ - 4.2.1.126 ko:K07106 ko00520,ko01100,map00520,map01100 - R08555 RC00397,RC00746 ko00000,ko00001,ko01000 - - - SIS,SIS_2 k141_14498_12 1042377.AFPJ01000036_gene1150 2.97e-107 324.0 COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,1RPAB@1236|Gammaproteobacteria,469E2@72275|Alteromonadaceae 1236|Gammaproteobacteria C Glycolate oxidase iron-sulfur subunit glcF - - ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001 - - - CCG,Fer4_7,Fer4_8 k141_28799_1 1279017.AQYJ01000026_gene239 7.19e-93 285.0 COG1524@1|root,COG1524@2|Bacteria,1PR75@1224|Proteobacteria,1RZUP@1236|Gammaproteobacteria,469K5@72275|Alteromonadaceae 1236|Gammaproteobacteria S Type I phosphodiesterase / nucleotide pyrophosphatase - - - - - - - - - - - - Phosphodiest k141_2631_1 1462526.BN990_02936 5.59e-101 308.0 COG1231@1|root,COG1231@2|Bacteria,1TRJC@1239|Firmicutes,4HBN4@91061|Bacilli 91061|Bacilli E Monoamine oxidase - - 1.4.3.4 ko:K00274 ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034 M00135 R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354 RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713 ko00000,ko00001,ko00002,ko01000 - - - Amino_oxidase k141_14499_1 223926.28807228 5.19e-141 417.0 COG1298@1|root,COG1298@2|Bacteria,1MUF3@1224|Proteobacteria,1RMSM@1236|Gammaproteobacteria,1XSJN@135623|Vibrionales 135623|Vibrionales N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin flhA - - ko:K02400 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 - - FHIPEP k141_15697_2 1279017.AQYJ01000029_gene3374 1.15e-86 256.0 COG2332@1|root,COG2332@2|Bacteria,1RHN5@1224|Proteobacteria,1S5VA@1236|Gammaproteobacteria,467DA@72275|Alteromonadaceae 1236|Gammaproteobacteria O Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH ccmE GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006807,GO:0006810,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015886,GO:0016020,GO:0016043,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0019538,GO:0020037,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046906,GO:0048037,GO:0051179,GO:0051181,GO:0051234,GO:0065003,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0071944,GO:0097159,GO:0098552,GO:0098567,GO:1901363,GO:1901564,GO:1901678 - ko:K02197 - - - - ko00000 - - iSSON_1240.SSON_2255 CcmE k141_4941_1 1121937.AUHJ01000006_gene2390 5.55e-88 274.0 COG0334@1|root,COG0334@2|Bacteria,1MUMF@1224|Proteobacteria,1RPUZ@1236|Gammaproteobacteria,4649P@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the Glu Leu Phe Val dehydrogenases family gdhA GO:0003674,GO:0003824,GO:0004353,GO:0004354,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.4 ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 - R00248 RC00006,RC02799 ko00000,ko00001,ko01000 - - iECH74115_1262.ECH74115_2481,iECSP_1301.ECSP_2329,iECs_1301.ECs2467,iG2583_1286.G2583_2207,iPC815.YPO3971,iSDY_1059.SDY_1514,iYL1228.KPN_01210,iZ_1308.Z2793 ELFV_dehydrog,ELFV_dehydrog_N k141_37020_1 1116375.VEJY3_14875 2.63e-100 302.0 COG0534@1|root,COG0534@2|Bacteria,1MV6B@1224|Proteobacteria,1RPGF@1236|Gammaproteobacteria,1XSWY@135623|Vibrionales 135623|Vibrionales V Na driven multidrug efflux pump dinF - - ko:K03327 - - - - ko00000,ko02000 2.A.66.1 - - MatE k141_37020_2 1219076.N646_2041 1.65e-156 442.0 COG3315@1|root,COG3315@2|Bacteria,1R810@1224|Proteobacteria,1S28Z@1236|Gammaproteobacteria,1XSP0@135623|Vibrionales 135623|Vibrionales H COG3315 O-Methyltransferase involved in polyketide biosynthesis VP2944 - - - - - - - - - - - LCM k141_37020_3 223926.28807971 2.23e-139 394.0 COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,1RMXF@1236|Gammaproteobacteria,1XV2V@135623|Vibrionales 135623|Vibrionales K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair lexA GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006282,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0048583,GO:0050789,GO:0050794,GO:0051052,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0080134,GO:0080135,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001020,GO:2001141 3.4.21.88 ko:K01356 - M00729 - - ko00000,ko00002,ko01000,ko01002,ko03400 - - - LexA_DNA_bind,Peptidase_S24 k141_13322_2 218284.CCDN010000002_gene2009 4.61e-21 93.2 COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,4HABE@91061|Bacilli,1ZPZA@1386|Bacillus 91061|Bacilli EF Carbamoyl-phosphate synthetase ammonia chain carB GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS k141_16841_1 675812.VHA_002553 0.0 1640.0 COG3250@1|root,COG3250@2|Bacteria,1MVBN@1224|Proteobacteria,1RMER@1236|Gammaproteobacteria,1XUKN@135623|Vibrionales 135623|Vibrionales G COG3250 Beta-galactosidase beta-glucuronidase ebgA - 3.2.1.23 ko:K12111 ko00052,ko00511,ko01100,map00052,map00511,map01100 - R01678,R06114 RC00049 ko00000,ko00001,ko01000 - - - Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N k141_22794_1 1453501.JELR01000002_gene451 5.34e-37 125.0 COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,4689P@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG1278 Cold shock proteins cspA - - ko:K03704 - - - - ko00000,ko03000 - - - CSD k141_311_1 218284.CCDN010000002_gene2203 1.75e-104 305.0 COG3764@1|root,COG3764@2|Bacteria,1V79B@1239|Firmicutes,4HJ8C@91061|Bacilli,1ZHDM@1386|Bacillus 91061|Bacilli M Sortase family - - - - - - - - - - - - Sortase k141_311_2 240302.BN982_02298 6.39e-27 100.0 2DGZH@1|root,2ZXV8@2|Bacteria,1W48K@1239|Firmicutes,4I1II@91061|Bacilli,3NG73@45667|Halobacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_28801_2 1121121.KB894304_gene3287 4.23e-56 178.0 2DQUM@1|root,338RX@2|Bacteria,1VFJH@1239|Firmicutes,4HXJ2@91061|Bacilli,270D4@186822|Paenibacillaceae 91061|Bacilli S Helix-turn-helix domain - - - - - - - - - - - - HTH_36 k141_7364_1 1116375.VEJY3_17361 1.65e-181 507.0 COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,1RNVM@1236|Gammaproteobacteria,1XU4P@135623|Vibrionales 135623|Vibrionales S Belongs to the pirin family - - - ko:K06911 - - - - ko00000 - - - Pirin,Pirin_C k141_7364_2 1219076.N646_3843 4.81e-44 142.0 COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,1XYBB@135623|Vibrionales 135623|Vibrionales K COG1278 Cold shock proteins - - - ko:K03704 - - - - ko00000,ko03000 - - - CSD k141_7364_3 1219076.N646_3842 3.07e-29 105.0 28TJ4@1|root,31NTU@2|Bacteria,1QKHY@1224|Proteobacteria,1TIN3@1236|Gammaproteobacteria,1XZD0@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_7364_4 1219076.N646_3841 2.54e-16 71.2 2BQG4@1|root,32JBI@2|Bacteria,1QMQS@1224|Proteobacteria,1TK0E@1236|Gammaproteobacteria,1Y1X8@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_565_2 1307436.PBF_22277 1.04e-133 394.0 COG1305@1|root,COG1305@2|Bacteria,1UYBU@1239|Firmicutes,4HBQQ@91061|Bacilli,1ZC8K@1386|Bacillus 91061|Bacilli E Transglutaminase-like superfamily - - - - - - - - - - - - Transglut_core k141_31308_1 1294265.JCM21738_4536 9.09e-114 331.0 COG0861@1|root,COG0861@2|Bacteria,1TQ09@1239|Firmicutes,4HB99@91061|Bacilli,1ZBPQ@1386|Bacillus 91061|Bacilli P COG0861 Membrane protein TerC, possibly involved in tellurium resistance ykoY - - - - - - - - - - - TerC k141_11172_1 985665.HPL003_08550 9.15e-11 59.7 COG2259@1|root,COG2259@2|Bacteria,1V7TX@1239|Firmicutes,4HJ1T@91061|Bacilli,26YB6@186822|Paenibacillaceae 91061|Bacilli S PFAM DoxX family protein ydfP - - ko:K15977 - - - - ko00000 - - - DoxX k141_11172_2 1246484.D479_02712 6.13e-29 112.0 COG2059@1|root,COG2059@2|Bacteria,1TSKA@1239|Firmicutes,4HBB1@91061|Bacilli,3NDY4@45667|Halobacillus 91061|Bacilli P Chromate transporter chr - - ko:K07240 - - - - ko00000,ko02000 2.A.51.1 - - Chromate_transp k141_7522_1 218284.CCDN010000001_gene453 1.62e-52 171.0 COG2207@1|root,COG2207@2|Bacteria,1UZ0B@1239|Firmicutes,4HBRQ@91061|Bacilli,1ZE9J@1386|Bacillus 91061|Bacilli K AraC family transcriptional regulator - - - - - - - - - - - - HTH_18,HTH_AraC k141_7522_2 933115.GPDM_08155 1.18e-11 66.6 COG1404@1|root,COG1404@2|Bacteria,1TSRI@1239|Firmicutes,4HBFB@91061|Bacilli,26E1U@186818|Planococcaceae 91061|Bacilli M Belongs to the peptidase S8 family - - 3.4.21.62 ko:K01342 ko02024,map02024 - - - ko00000,ko00001,ko01000,ko01002,ko03110 - - - Peptidase_S8 k141_9988_1 1453501.JELR01000002_gene1212 8e-47 155.0 COG2433@1|root,COG2433@2|Bacteria,1N0ZS@1224|Proteobacteria,1SBFE@1236|Gammaproteobacteria,46CTE@72275|Alteromonadaceae 1236|Gammaproteobacteria S Pfam Transposase IS66 - - - - - - - - - - - - - k141_9988_2 1453501.JELR01000002_gene1211 1.49e-143 406.0 COG0461@1|root,COG0461@2|Bacteria,1MW6F@1224|Proteobacteria,1RQYG@1236|Gammaproteobacteria,4643W@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) pyrE GO:0000287,GO:0003674,GO:0003824,GO:0004588,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.10 ko:K00762 ko00240,ko01100,map00240,map01100 M00051 R01870 RC00611 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_2819,iECIAI39_1322.ECIAI39_4161,iEcSMS35_1347.EcSMS35_3977,iUTI89_1310.UTI89_C4186 Pribosyltran k141_15864_2 1246484.D479_09260 2.23e-52 166.0 COG0089@1|root,COG0089@2|Bacteria,1VA4W@1239|Firmicutes,4HKCV@91061|Bacilli,3NF6Y@45667|Halobacillus 91061|Bacilli J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome rplW GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02892 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L23 k141_5221_1 935836.JAEL01000024_gene2426 8.71e-78 247.0 COG3920@1|root,COG3920@2|Bacteria,1TRK3@1239|Firmicutes,4HAMI@91061|Bacilli,1ZC5C@1386|Bacillus 91061|Bacilli T Histidine kinase pdtaS - 2.7.13.3 ko:K00936 - M00839 - - ko00000,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HATPase_c_2,H_kinase_N,HisKA_2 k141_4079_1 935836.JAEL01000034_gene4397 4.61e-59 191.0 COG4912@1|root,COG4912@2|Bacteria,1TSAW@1239|Firmicutes,4HABR@91061|Bacilli,1ZBJS@1386|Bacillus 91061|Bacilli L DNA alkylation repair - - - - - - - - - - - - DNA_alkylation k141_4079_2 935836.JAEL01000004_gene2567 8.37e-12 64.7 COG0477@1|root,COG2814@2|Bacteria,1TRZB@1239|Firmicutes,4HC28@91061|Bacilli,1ZD6T@1386|Bacillus 91061|Bacilli EGP Transmembrane secretion effector ykuC1 - - ko:K08217 - - - - br01600,ko00000,ko01504,ko02000 2.A.1.21.1,2.A.1.21.22 - - MFS_1,MFS_3 k141_27634_1 1279017.AQYJ01000023_gene3156 1.36e-47 161.0 COG0491@1|root,COG0491@2|Bacteria 2|Bacteria GM Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - - - - - - - - - - Lactamase_B k141_27634_2 1265503.KB905175_gene4027 1.71e-159 461.0 COG0786@1|root,COG0786@2|Bacteria,1MVBC@1224|Proteobacteria,1RP0S@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Catalyzes the sodium-dependent transport of glutamate gltS - - ko:K03312 - - - - ko00000,ko02000 2.A.27 - - Glt_symporter k141_20600_1 1280001.BAOA01000038_gene4410 9.26e-38 139.0 COG2199@1|root,COG3706@2|Bacteria,1MXAW@1224|Proteobacteria,1RZ41@1236|Gammaproteobacteria,1XSZZ@135623|Vibrionales 135623|Vibrionales T COG2199 FOG GGDEF domain VP0699 - - - - - - - - - - - GGDEF k141_20600_2 1116375.VEJY3_03225 1.38e-176 512.0 COG0457@1|root,COG0457@2|Bacteria,1RDRI@1224|Proteobacteria,1S3PB@1236|Gammaproteobacteria,1XTIH@135623|Vibrionales 135623|Vibrionales S COG0457 FOG TPR repeat - - - - - - - - - - - - TPR_12 k141_6460_1 997296.PB1_16159 4.08e-46 169.0 COG3209@1|root,COG3209@2|Bacteria 2|Bacteria M self proteolysis - - - - - - - - - - - - - k141_11173_2 218284.CCDN010000001_gene1078 2.56e-76 233.0 COG0517@1|root,COG0517@2|Bacteria,1TR5G@1239|Firmicutes,4H9ZA@91061|Bacilli,1ZD7H@1386|Bacillus 91061|Bacilli S CBS domain - - - - - - - - - - - - CBS k141_28952_1 1042377.AFPJ01000036_gene1140 9.65e-135 388.0 COG1737@1|root,COG1737@2|Bacteria,1ND5W@1224|Proteobacteria,1RNCI@1236|Gammaproteobacteria,46B7G@72275|Alteromonadaceae 1236|Gammaproteobacteria K Helix-turn-helix domain, rpiR family yfhH GO:0003674,GO:0003700,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K15835 - - - - ko00000,ko03000 - - - HTH_6,SIS k141_9989_1 247634.GPB2148_400 2.47e-79 263.0 COG1629@1|root,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria,1J5SG@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec k141_23114_1 1004785.AMBLS11_02525 7.59e-15 69.3 2EHRX@1|root,33BHN@2|Bacteria,1NG91@1224|Proteobacteria,1SGIP@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_19462_2 1279017.AQYJ01000027_gene1599 9.43e-84 249.0 COG0816@1|root,COG0816@2|Bacteria,1RDHZ@1224|Proteobacteria,1S96Q@1236|Gammaproteobacteria,466VN@72275|Alteromonadaceae 1236|Gammaproteobacteria L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA yqgF GO:0000966,GO:0000967,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - ko:K07447 - - - - ko00000,ko01000 - - - RuvX k141_31309_1 997296.PB1_13074 8.37e-25 94.4 2CGYI@1|root,32YUY@2|Bacteria,1VGI2@1239|Firmicutes,4HPBN@91061|Bacilli,1ZJ06@1386|Bacillus 91061|Bacilli S Cold-inducible protein YdjO - - - - - - - - - - - - YdjO k141_32423_3 1121935.AQXX01000078_gene1560 9.47e-81 254.0 COG1757@1|root,COG1757@2|Bacteria,1MX0T@1224|Proteobacteria,1RN8E@1236|Gammaproteobacteria,1XHAY@135619|Oceanospirillales 135619|Oceanospirillales C Na H antiporter - - - - - - - - - - - - Na_H_antiporter k141_30055_1 1279017.AQYJ01000022_gene2638 1.88e-210 589.0 COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,1RMJF@1236|Gammaproteobacteria,4647M@72275|Alteromonadaceae 1236|Gammaproteobacteria D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP mrp GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K03593 - - - - ko00000,ko03029,ko03036 - - - FeS_assembly_P,ParA k141_30055_2 1122197.ATWI01000008_gene2686 1.67e-05 48.1 COG1054@1|root,COG1054@2|Bacteria,1MUFV@1224|Proteobacteria,1RNNU@1236|Gammaproteobacteria,464T0@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the UPF0176 family yceA - - ko:K07146 - - - - ko00000 - - - Rhodanese,Rhodanese_C k141_26797_1 1116375.VEJY3_08080 3.94e-275 757.0 COG0582@1|root,COG0582@2|Bacteria,1RAN4@1224|Proteobacteria,1S5SI@1236|Gammaproteobacteria,1XXR0@135623|Vibrionales 135623|Vibrionales L Phage integrase family - - - - - - - - - - - - Phage_integrase k141_4080_1 1215915.BN193_00525 1.03e-13 73.2 COG1309@1|root,COG1309@2|Bacteria,1V59K@1239|Firmicutes,4HHCP@91061|Bacilli,1YBNT@1357|Lactococcus 91061|Bacilli K Transcriptional regulator C-terminal region - - - - - - - - - - - - TetR_C_8,TetR_N k141_17063_2 1453501.JELR01000001_gene1901 2.02e-256 715.0 COG2114@1|root,COG2114@2|Bacteria,1MV1V@1224|Proteobacteria,1SZ0N@1236|Gammaproteobacteria,46CIY@72275|Alteromonadaceae 1236|Gammaproteobacteria T Adenylyl- / guanylyl cyclase, catalytic domain - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_cyc,HAMP k141_17063_3 1042377.AFPJ01000009_gene327 5.87e-290 802.0 COG0028@1|root,COG0028@2|Bacteria,1MWVW@1224|Proteobacteria,1RPZ2@1236|Gammaproteobacteria,465G8@72275|Alteromonadaceae 1236|Gammaproteobacteria EH Thiamine pyrophosphate enzyme, central domain - - 2.2.1.6,4.1.1.75 ko:K01652,ko:K12253 ko00290,ko00330,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00330,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R03178,R04672,R04673,R08648 RC00027,RC00106,RC00506,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N k141_17063_4 1042377.AFPJ01000009_gene326 1.16e-174 494.0 COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RNN0@1236|Gammaproteobacteria,467I6@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0436 Aspartate tyrosine aromatic aminotransferase aspC - 2.6.1.1,2.6.1.84 ko:K00812,ko:K12252 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 - R00355,R00694,R00734,R00896,R02433,R02619,R05052,R08197 RC00006,RC00008 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 k141_11174_1 545693.BMQ_2153 3.88e-61 203.0 COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,4H9T1@91061|Bacilli,1ZE6W@1386|Bacillus 91061|Bacilli M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan murE - 6.3.2.13 ko:K01928 ko00300,ko00550,map00300,map00550 - R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M k141_7524_1 1294265.JCM21738_409 3.7e-31 114.0 COG0621@1|root,COG0621@2|Bacteria,1TNYN@1239|Firmicutes,4HAAS@91061|Bacilli,1ZBMF@1386|Bacillus 91061|Bacilli J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine miaB GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035597,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360 2.8.4.3 ko:K06168 - - R10645,R10646,R10647 RC00003,RC00980,RC03221,RC03222 ko00000,ko01000,ko03016 - - - Radical_SAM,TRAM,UPF0004 k141_7524_2 1294265.JCM21738_410 1.1e-64 199.0 COG4550@1|root,COG4550@2|Bacteria,1V4W0@1239|Firmicutes,4HH6Y@91061|Bacilli,1ZG72@1386|Bacillus 91061|Bacilli S Belongs to the UPF0342 family ymcA - 3.6.3.21 ko:K02028 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - Com_YlbF k141_24167_1 1121935.AQXX01000117_gene5115 3.14e-94 291.0 COG1706@1|root,COG1706@2|Bacteria,1MVKW@1224|Proteobacteria,1RMRB@1236|Gammaproteobacteria,1XIS3@135619|Oceanospirillales 135619|Oceanospirillales N Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation - - - ko:K02394 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FlgI k141_24167_2 522373.Smlt2311 4.37e-20 92.0 COG2063@1|root,COG2063@2|Bacteria,1RDEY@1224|Proteobacteria,1S3XK@1236|Gammaproteobacteria,1X4EI@135614|Xanthomonadales 135614|Xanthomonadales N Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation flgH - - ko:K02393 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FlgH k141_24167_4 1187851.A33M_1052 2.1e-43 152.0 COG4786@1|root,COG4786@2|Bacteria,1MVMA@1224|Proteobacteria,2TRR4@28211|Alphaproteobacteria,3FCX9@34008|Rhodovulum 28211|Alphaproteobacteria N Flagella basal body rod protein flgG - - ko:K02392 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C k141_9990_1 223926.28809033 1.76e-72 220.0 2E01C@1|root,32VQM@2|Bacteria,1N20N@1224|Proteobacteria,1SACC@1236|Gammaproteobacteria,1XTFG@135623|Vibrionales 135623|Vibrionales S YcxB-like protein VPA0798 - - - - - - - - - - - YcxB k141_12482_2 1517681.HW45_10560 2.41e-107 320.0 COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,1RMJ1@1236|Gammaproteobacteria,1XTXF@135623|Vibrionales 135623|Vibrionales L Belongs to the 'phage' integrase family - - - - - - - - - - - - Arm-DNA-bind_3,Phage_int_SAM_3,Phage_integrase k141_20601_1 1347086.CCBA010000011_gene1657 2e-81 246.0 COG0410@1|root,COG0410@2|Bacteria,1TPW4@1239|Firmicutes,4HABJ@91061|Bacilli,1ZDVC@1386|Bacillus 91061|Bacilli E branched-chain amino acid - - - ko:K01996 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran k141_20601_2 1347086.CCBA010000011_gene1656 3.16e-50 165.0 COG0411@1|root,COG0411@2|Bacteria,1TR0P@1239|Firmicutes,4HASG@91061|Bacilli,1ZB0Q@1386|Bacillus 91061|Bacilli E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component - - - ko:K01995 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C k141_37219_2 218284.CCDN010000005_gene3316 1.42e-134 391.0 COG0491@1|root,COG0491@2|Bacteria,1TT3D@1239|Firmicutes,4HDKE@91061|Bacilli,1ZCQE@1386|Bacillus 91061|Bacilli S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B k141_37219_3 218284.CCDN010000005_gene3317 8.29e-69 214.0 COG2323@1|root,COG2323@2|Bacteria,1UYR2@1239|Firmicutes,4HFCN@91061|Bacilli,1ZFK2@1386|Bacillus 91061|Bacilli S membrane yetF - - - - - - - - - - - DUF421 k141_25476_1 268407.PWYN_07355 8.68e-06 52.8 2DB8D@1|root,2Z7RF@2|Bacteria,1TS15@1239|Firmicutes,4HE8Q@91061|Bacilli,26VJS@186822|Paenibacillaceae 91061|Bacilli S TIGRFAM germination protein, Ger(x)C family - - - ko:K06297 - - - - ko00000 - - - Spore_GerAC k141_25476_2 265729.GS18_0212990 9.95e-44 162.0 COG0531@1|root,COG0531@2|Bacteria,1V1FX@1239|Firmicutes,4HFZN@91061|Bacilli,1ZFS6@1386|Bacillus 91061|Bacilli E Spore germination protein gerKB - - - - - - - - - - - Spore_permease k141_25476_3 717606.PaecuDRAFT_1135 2.9e-172 500.0 COG0619@1|root,COG0619@2|Bacteria,1VBW7@1239|Firmicutes,4HCFC@91061|Bacilli,2779M@186822|Paenibacillaceae 91061|Bacilli P PFAM GerA spore germination protein - - - ko:K06295 - - - - ko00000 - - - GerA k141_25476_4 574376.BAMA_12815 9.75e-13 68.2 COG4585@1|root,COG4585@2|Bacteria,1V3N2@1239|Firmicutes,4HHKF@91061|Bacilli,1ZDEM@1386|Bacillus 91061|Bacilli T Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - - - - - - - - - - GAF,HATPase_c,HisKA_3 k141_19481_1 218284.CCDN010000001_gene795 2.75e-108 316.0 COG3330@1|root,COG3330@2|Bacteria,1V2ZT@1239|Firmicutes,4I257@91061|Bacilli,1ZG55@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF4912) - - - ko:K09942 - - - - ko00000 - - - DUF4912 k141_27652_1 1307436.PBF_12522 7.14e-100 291.0 COG3546@1|root,COG3546@2|Bacteria,1TQVQ@1239|Firmicutes,4HA34@91061|Bacilli,1ZQQY@1386|Bacillus 91061|Bacilli P Spore Coat cotJC - - ko:K06334 - - - - ko00000 - - - Mn_catalase k141_8837_1 1242864.D187_009906 4.26e-25 104.0 COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,42MZZ@68525|delta/epsilon subdivisions,2WIQI@28221|Deltaproteobacteria,2YUSK@29|Myxococcales 28221|Deltaproteobacteria H MoeA C-terminal region (domain IV) - - 2.10.1.1 ko:K03750 ko00790,ko01100,map00790,map01100 - R09735 RC03462 ko00000,ko00001,ko01000 - - - MoCF_biosynth,MoeA_C,MoeA_N k141_8837_2 649349.Lbys_1587 0.000149 44.7 COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,4NHG0@976|Bacteroidetes,47JZ1@768503|Cytophagia 976|Bacteroidetes M PFAM Transglycosylase SLT domain - - - ko:K08307 - - - - ko00000,ko01000,ko01011 - - - LysM,SLT k141_30069_1 218284.CCDN010000002_gene2646 2.16e-142 421.0 COG1762@1|root,COG3711@1|root,COG1762@2|Bacteria,COG3711@2|Bacteria,1TQT1@1239|Firmicutes,4H9N4@91061|Bacilli,1ZBCM@1386|Bacillus 91061|Bacilli GKT COG3711 Transcriptional antiterminator - - 2.7.1.194 ko:K02821 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 M00283,M00550 R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.7.1 - - HTH_11,Mga,PRD,PTS_EIIA_2,PTS_IIB k141_31324_1 768066.HELO_3958 5.15e-80 248.0 COG0599@1|root,COG2267@1|root,COG0599@2|Bacteria,COG2267@2|Bacteria,1MX0N@1224|Proteobacteria,1RYSX@1236|Gammaproteobacteria,1XPBH@135619|Oceanospirillales 135619|Oceanospirillales I Alpha/beta hydrolase family - - 3.1.1.24,4.1.1.44 ko:K14727 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00568 R02991,R03470 RC00825,RC00938 ko00000,ko00001,ko00002,ko01000 - - - Abhydrolase_1,Abhydrolase_6,CMD k141_31324_2 1397528.Q671_14465 5.35e-15 73.2 COG0583@1|root,COG0583@2|Bacteria,1MX53@1224|Proteobacteria,1RS04@1236|Gammaproteobacteria,1XK5G@135619|Oceanospirillales 135619|Oceanospirillales K transcriptional regulator - - - ko:K02623 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate k141_26817_1 1196031.ALEG01000028_gene4157 4.85e-20 84.3 COG4821@1|root,COG4821@2|Bacteria,1VJUP@1239|Firmicutes,4HP1J@91061|Bacilli,1ZH7S@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF2529) ywjG - - - - - - - - - - - DUF2529 k141_26817_2 1294265.JCM21738_3478 2.03e-70 221.0 COG0504@1|root,COG0504@2|Bacteria,1TP34@1239|Firmicutes,4H9X6@91061|Bacilli,1ZB0S@1386|Bacillus 91061|Bacilli F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates pyrG - 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 - - - CTP_synth_N,GATase k141_1590_1 1116375.VEJY3_06735 3.96e-130 372.0 COG1802@1|root,COG1802@2|Bacteria,1R96W@1224|Proteobacteria,1RS75@1236|Gammaproteobacteria,1XUFP@135623|Vibrionales 135623|Vibrionales K COG1802 Transcriptional regulators - - - - - - - - - - - - FCD,GntR k141_21853_1 1453501.JELR01000001_gene2949 7.39e-132 400.0 COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,1RNEB@1236|Gammaproteobacteria,465F9@72275|Alteromonadaceae 1236|Gammaproteobacteria J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner valS GO:0000287,GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006417,GO:0006418,GO:0006438,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0034248,GO:0034250,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045903,GO:0046483,GO:0046872,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0052689,GO:0060255,GO:0061475,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:2000112 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iECH74115_1262.ECH74115_5779,iECNA114_1301.ECNA114_4481,iECO26_1355.ECO26_5428,iECSP_1301.ECSP_5359,iECs_1301.ECs5235,iG2583_1286.G2583_5088,iJN746.PP_0977,iSBO_1134.SBO_4182,iSSON_1240.SSON_4443,iYL1228.KPN_04663,iZ_1308.Z5870 Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 k141_23155_1 218284.CCDN010000001_gene1064 1.4e-139 409.0 COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HBZ0@91061|Bacilli,1ZAQC@1386|Bacillus 91061|Bacilli T Histidine kinase resE - 2.7.13.3 ko:K07651 ko02020,map02020 M00458 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,PAS,PAS_4 k141_2796_1 218284.CCDN010000001_gene1900 2.42e-05 45.1 COG0528@1|root,COG0528@2|Bacteria,1TPXN@1239|Firmicutes,4H9UB@91061|Bacilli,1ZBMW@1386|Bacillus 91061|Bacilli F Catalyzes the reversible phosphorylation of UMP to UDP pyrH - 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 - R00158 RC00002 ko00000,ko00001,ko01000 - - iSB619.SA_RS06240 AA_kinase k141_2796_2 218284.CCDN010000001_gene1901 1.67e-102 303.0 COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,4HBDV@91061|Bacilli,1ZB7R@1386|Bacillus 91061|Bacilli J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome tsf GO:0001871,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005623,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0019538,GO:0030246,GO:0030247,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 - ko:K02357 - - - - ko00000,ko03012,ko03029 - - - EF_TS k141_36022_1 42565.FP66_07365 8.5e-48 153.0 COG2900@1|root,COG2900@2|Bacteria,1NGFM@1224|Proteobacteria,1SGAM@1236|Gammaproteobacteria,1XMNQ@135619|Oceanospirillales 135619|Oceanospirillales S Belongs to the SlyX family slyX - - ko:K03745 - - - - ko00000 - - - SlyX k141_36022_2 42565.FP66_07360 1.38e-23 92.8 COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,1XKUQ@135619|Oceanospirillales 135619|Oceanospirillales K Cold-shock' - - - ko:K03704 - - - - ko00000,ko03000 - - - CSD k141_11206_1 1405.DJ92_1804 9.97e-71 215.0 COG3832@1|root,COG3832@2|Bacteria,1V7US@1239|Firmicutes,4HK0E@91061|Bacilli,1ZGHK@1386|Bacillus 91061|Bacilli S Activator of Hsp90 ATPase homolog 1-like protein yndB - - - - - - - - - - - AHSA1 k141_13674_1 1042377.AFPJ01000036_gene1137 0.0 1001.0 COG1629@1|root,COG1629@2|Bacteria,1MVSG@1224|Proteobacteria,1RS33@1236|Gammaproteobacteria,46A68@72275|Alteromonadaceae 1236|Gammaproteobacteria P Carboxypeptidase regulatory-like domain - - - - - - - - - - - - CarboxypepD_reg k141_6466_1 1348635.BBJY01000001_gene2411 4.45e-58 181.0 COG5470@1|root,COG5470@2|Bacteria,1RIH6@1224|Proteobacteria,1S63X@1236|Gammaproteobacteria,1XXSG@135623|Vibrionales 135623|Vibrionales S NIPSNAP - - - - - - - - - - - - NIPSNAP k141_6466_2 314292.VAS14_02216 5.09e-142 404.0 COG0384@1|root,COG0384@2|Bacteria,1RKBN@1224|Proteobacteria,1S7UA@1236|Gammaproteobacteria,1XV1T@135623|Vibrionales 135623|Vibrionales S Phenazine biosynthesis-like protein - - - - - - - - - - - - PhzC-PhzF k141_6466_3 796620.VIBC2010_15219 7.47e-84 248.0 COG3791@1|root,COG3791@2|Bacteria,1PSHH@1224|Proteobacteria,1SB5F@1236|Gammaproteobacteria,1Y2RK@135623|Vibrionales 135623|Vibrionales S Glutathione-dependent formaldehyde-activating enzyme - - - - - - - - - - - - GFA k141_6466_4 1348635.BBJY01000001_gene2336 1.03e-148 421.0 COG0518@1|root,COG0518@2|Bacteria,1MUDH@1224|Proteobacteria,1RXUZ@1236|Gammaproteobacteria,1XW7Y@135623|Vibrionales 135623|Vibrionales F Glutamine amidotransferase class-I - - 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase k141_6466_5 1116375.VEJY3_20711 2.46e-154 436.0 COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1R7M5@1224|Proteobacteria,1S1A2@1236|Gammaproteobacteria,1Y2JR@135623|Vibrionales 135623|Vibrionales K helix_turn_helix, arabinose operon control protein - - - - - - - - - - - - HTH_18 k141_6466_6 1219072.VHA01S_085_00030 3.94e-76 234.0 COG1280@1|root,COG1280@2|Bacteria,1RASZ@1224|Proteobacteria,1SBCJ@1236|Gammaproteobacteria,1Y2PA@135623|Vibrionales 135623|Vibrionales P LysE type translocator - - - - - - - - - - - - LysE k141_6466_7 1219072.VHA01S_085_00020 6.29e-132 381.0 COG2207@1|root,COG2207@2|Bacteria,1R3ZW@1224|Proteobacteria,1S2Y4@1236|Gammaproteobacteria,1XSP8@135623|Vibrionales 135623|Vibrionales K COG2207 AraC-type DNA-binding domain-containing proteins - - - - - - - - - - - - AraC_binding,HTH_18 k141_25478_1 1117647.M5M_17095 1.44e-45 155.0 COG3208@1|root,COG3208@2|Bacteria,1R027@1224|Proteobacteria,1T4E8@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q Thioesterase involved in non-ribosomal peptide biosynthesis - - - - - - - - - - - - Abhydrolase_1 k141_18366_1 1279017.AQYJ01000024_gene861 7.07e-159 472.0 COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,1RM9X@1236|Gammaproteobacteria,46433@72275|Alteromonadaceae 1236|Gammaproteobacteria J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019538,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034645,GO:0036094,GO:0043021,GO:0043024,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:0097216,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N,IF2_assoc k141_28973_1 223926.28805645 6.83e-34 130.0 COG3156@1|root,COG3156@2|Bacteria,1QJFS@1224|Proteobacteria,1THF6@1236|Gammaproteobacteria,1XV93@135623|Vibrionales 135623|Vibrionales U type II secretion system protein K VP0659 - - - - - - - - - - - - k141_28973_2 29495.EA26_04065 3.51e-45 155.0 COG4795@1|root,COG4795@2|Bacteria,1QUXH@1224|Proteobacteria,1SI8K@1236|Gammaproteobacteria,1Y33I@135623|Vibrionales 135623|Vibrionales U General secretion pathway protein - - - ko:K02672 - - - - ko00000,ko02035,ko02044 - - - N_methyl k141_23156_1 1116375.VEJY3_06550 1.93e-52 183.0 COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,1RNB7@1236|Gammaproteobacteria,1XTUF@135623|Vibrionales 135623|Vibrionales S metal-dependent hydrolase with the TIM-barrel fold - - - - - - - - - - - - Amidohydro_3 k141_30070_1 314265.R2601_10304 1.18e-161 456.0 COG2801@1|root,COG2963@1|root,COG2801@2|Bacteria,COG2963@2|Bacteria,1PBHA@1224|Proteobacteria,2TRQF@28211|Alphaproteobacteria 28211|Alphaproteobacteria L COG2801 Transposase and inactivated derivatives - - - - - - - - - - - - HTH_32,rve,rve_3 k141_21854_1 1294265.JCM21738_964 8.72e-110 321.0 COG1445@1|root,COG1762@1|root,COG1445@2|Bacteria,COG1762@2|Bacteria,1UJ3M@1239|Firmicutes,4IT0X@91061|Bacilli,1ZSIZ@1386|Bacillus 91061|Bacilli GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 - - 2.7.1.202 ko:K02768,ko:K02769 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1 - - PTS_EIIA_2,PTS_IIB k141_7547_1 218284.CCDN010000004_gene3153 8.71e-133 388.0 COG0189@1|root,COG0189@2|Bacteria,1V1EV@1239|Firmicutes,4HFNI@91061|Bacilli,1ZBM5@1386|Bacillus 91061|Bacilli HJ YheC/D like ATP-grasp - - - - - - - - - - - - ATPgrasp_YheCD k141_26819_1 866895.HBHAL_1338 3.52e-106 315.0 COG1597@1|root,COG1597@2|Bacteria,1TQ9A@1239|Firmicutes,4HCPU@91061|Bacilli,3ND8V@45667|Halobacillus 91061|Bacilli I Diacylglycerol kinase catalytic domain (presumed) yegS - - - - - - - - - - - DAGK_cat k141_23157_1 218284.CCDN010000001_gene1594 1.68e-105 310.0 COG2362@1|root,COG2362@2|Bacteria,1TSUZ@1239|Firmicutes,4HC5R@91061|Bacilli,1ZC41@1386|Bacillus 91061|Bacilli E D-aminopeptidase dppA - - ko:K16203 - - - - ko00000,ko01000,ko01002 3.A.1.5.2 - iYO844.BSU12920 Peptidase_M55 k141_30071_1 218284.CCDN010000007_gene3830 1.4e-112 334.0 COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,4HA31@91061|Bacilli,1ZBNF@1386|Bacillus 91061|Bacilli O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain yyxA - 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Trypsin_2 k141_25480_1 218284.CCDN010000006_gene3726 8.25e-33 125.0 COG0768@1|root,COG0768@2|Bacteria,1TQHY@1239|Firmicutes,4H9MT@91061|Bacilli,1ZAX9@1386|Bacillus 91061|Bacilli M Penicillin-binding Protein pbpC - 3.4.16.4 ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 M00625 - - ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 - - - MecA_N,PBP_dimer,Transpeptidase k141_25480_2 218284.CCDN010000006_gene3725 4.16e-44 152.0 COG3320@1|root,COG3320@2|Bacteria,1TQPW@1239|Firmicutes,4HAFC@91061|Bacilli,1ZCU0@1386|Bacillus 91061|Bacilli Q Male sterility protein - - - - - - - - - - - - NAD_binding_4 k141_8840_1 1294265.JCM21738_4362 6.98e-141 408.0 COG1207@1|root,COG1207@2|Bacteria,1TP88@1239|Firmicutes,4H9V5@91061|Bacilli,1ZAVH@1386|Bacillus 91061|Bacilli M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain glmU GO:0000270,GO:0000271,GO:0003674,GO:0003824,GO:0003977,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006629,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0030203,GO:0033692,GO:0034637,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509 2.3.1.157,2.7.7.23 ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00362 R00416,R05332 RC00002,RC00004,RC00166 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transf_3,NTP_transferase k141_18368_1 1279017.AQYJ01000025_gene765 1.56e-57 199.0 28IUR@1|root,2Z8TE@2|Bacteria,1NW7C@1224|Proteobacteria,1RP4W@1236|Gammaproteobacteria,465G0@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_12522_1 1042377.AFPJ01000023_gene662 5.4e-39 132.0 2EQ5T@1|root,32ZV0@2|Bacteria,1NFTI@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_19482_1 637905.SVI_1747 5.38e-76 248.0 COG2267@1|root,COG2267@2|Bacteria,1QTZP@1224|Proteobacteria,1RPB9@1236|Gammaproteobacteria,2Q93K@267890|Shewanellaceae 1236|Gammaproteobacteria I Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_6,Hydrolase_4 k141_25801_3 1288826.MSNKSG1_14082 2.22e-152 432.0 COG3384@1|root,COG3384@2|Bacteria,1MXJZ@1224|Proteobacteria,1RR5P@1236|Gammaproteobacteria,4664C@72275|Alteromonadaceae 1236|Gammaproteobacteria S Catalytic LigB subunit of aromatic ring-opening dioxygenase - - - - - - - - - - - - LigB k141_31413_1 1232410.KI421428_gene1150 2.55e-276 762.0 COG3391@1|root,COG3391@2|Bacteria,1MXDX@1224|Proteobacteria 1224|Proteobacteria S Selenium-binding protein - - - ko:K17285 - - - - ko00000,ko04147 - - - SBP56 k141_31413_4 94624.Bpet4536 8.65e-11 63.9 COG0625@1|root,COG0625@2|Bacteria,1RHSK@1224|Proteobacteria,2VRHW@28216|Betaproteobacteria,3T3MY@506|Alcaligenaceae 28216|Betaproteobacteria O Glutathione S-transferase - - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C_2,GST_N_3 k141_7733_1 935837.JAEK01000015_gene5022 6.28e-46 155.0 COG0596@1|root,COG0596@2|Bacteria,1V9D7@1239|Firmicutes,4HK54@91061|Bacilli,1ZEVK@1386|Bacillus 91061|Bacilli S hydrolases or acyltransferases (alpha beta hydrolase superfamily) yqjL - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6,Hydrolase_4 k141_7733_2 218284.CCDN010000002_gene2287 2.33e-36 122.0 2EAEH@1|root,334I2@2|Bacteria,1VFBK@1239|Firmicutes,4HQKD@91061|Bacilli 91061|Bacilli S Domain of unknown function (DUF4177) - - - - - - - - - - - - DUF4177 k141_7733_3 218284.CCDN010000002_gene2288 1.54e-166 474.0 COG1472@1|root,COG1472@2|Bacteria,1TP63@1239|Firmicutes,4HBDB@91061|Bacilli,1ZCGR@1386|Bacillus 91061|Bacilli G Belongs to the glycosyl hydrolase 3 family nagZ - 3.2.1.52 ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 M00628 R00022,R05963,R07809,R07810,R10831 RC00049 ko00000,ko00001,ko00002,ko01000 - - - DUF4309,Glyco_hydro_3 k141_6687_1 1279017.AQYJ01000027_gene1573 2.2e-78 244.0 COG1600@1|root,COG1600@2|Bacteria,1MV1H@1224|Proteobacteria,1RMD9@1236|Gammaproteobacteria,46459@72275|Alteromonadaceae 1236|Gammaproteobacteria C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) queG GO:0003674,GO:0003824,GO:0006091,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009055,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0022900,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 ko:K18979 - - - - ko00000,ko01000,ko03016 - - - DUF1730,Fer4_16 k141_6687_2 1279017.AQYJ01000027_gene1572 1.47e-83 261.0 COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,1RMPS@1236|Gammaproteobacteria,4654W@72275|Alteromonadaceae 1236|Gammaproteobacteria G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration nnrD GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 - - - - ko00000,ko01000 - - - Carb_kinase,YjeF_N k141_17285_1 537007.BLAHAN_05712 5.93e-30 117.0 COG0571@1|root,COG0571@2|Bacteria,1TPGC@1239|Firmicutes,249QD@186801|Clostridia,3XZ9W@572511|Blautia 186801|Clostridia J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism rnc - 3.1.26.3 ko:K03685 ko03008,ko05205,map03008,map05205 - - - ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 - - - Ribonucleas_3_3,dsrm k141_19753_1 218284.CCDN010000001_gene1375 1.33e-92 284.0 COG1120@1|root,COG1120@2|Bacteria,1TP2Q@1239|Firmicutes,4HA28@91061|Bacilli,1ZASR@1386|Bacillus 91061|Bacilli HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components yvrA - 3.6.3.34 ko:K02013 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 - - ABC_tran,CbiZ k141_32665_1 1116375.VEJY3_02270 1.61e-310 850.0 COG1115@1|root,COG1115@2|Bacteria,1MUI3@1224|Proteobacteria,1RMNF@1236|Gammaproteobacteria,1XTS9@135623|Vibrionales 135623|Vibrionales U alanine symporter yaaJ - - ko:K03310 - - - - ko00000 2.A.25 - - Na_Ala_symp k141_32665_2 1219076.N646_2655 6.41e-32 111.0 2EJCD@1|root,33D3F@2|Bacteria,1NGUI@1224|Proteobacteria,1SHIH@1236|Gammaproteobacteria,1XZ06@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF3545) - - - - - - - - - - - - DUF3545 k141_29158_1 1117647.M5M_07525 5.39e-45 154.0 COG1737@1|root,COG1737@2|Bacteria,1ND5W@1224|Proteobacteria,1RNCI@1236|Gammaproteobacteria,1JA87@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria K Helix-turn-helix domain, rpiR family yfhH GO:0003674,GO:0003700,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K15835 - - - - ko00000,ko03000 - - - HTH_6,SIS k141_25802_1 203122.Sde_2500 7.56e-108 337.0 COG1501@1|root,COG1501@2|Bacteria,1MWNJ@1224|Proteobacteria,1RMJ9@1236|Gammaproteobacteria,465UA@72275|Alteromonadaceae 1236|Gammaproteobacteria G Belongs to the glycosyl hydrolase 31 family xylS - 2.4.1.161,3.2.1.177 ko:K01811,ko:K18820 - - - - ko00000,ko01000 - GH31 - DUF4968,DUF5110,Gal_mutarotas_2,Glyco_hydro_31,PA14 k141_7734_1 28229.ND2E_3990 1.63e-56 195.0 COG1228@1|root,COG1228@2|Bacteria,1PDWI@1224|Proteobacteria,1RXW9@1236|Gammaproteobacteria,2Q8CA@267889|Colwelliaceae 1236|Gammaproteobacteria Q Amidohydrolase family - - - - - - - - - - - - Amidohydro_1 k141_27870_1 639283.Snov_0436 6.79e-21 95.9 COG0668@1|root,COG0668@2|Bacteria,1MY0I@1224|Proteobacteria,2TSIN@28211|Alphaproteobacteria,3EZ0D@335928|Xanthobacteraceae 28211|Alphaproteobacteria M Mechanosensitive ion channel - - - ko:K22044 - - - - ko00000,ko02000 1.A.23.3 - - MS_channel k141_13984_2 1347369.CCAD010000094_gene2268 2.8e-85 263.0 COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,4H9MW@91061|Bacilli,1ZBKI@1386|Bacillus 91061|Bacilli L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids dnaA GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - ko:K02313 ko02020,ko04112,map02020,map04112 - - - ko00000,ko00001,ko03032,ko03036 - - - Bac_DnaA,Bac_DnaA_C,DnaA_N k141_29159_1 1042377.AFPJ01000043_gene887 6.53e-72 240.0 COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,1RYP9@1236|Gammaproteobacteria,465IE@72275|Alteromonadaceae 1236|Gammaproteobacteria E ERAP1-like C-terminal domain - - 3.4.11.14 ko:K01263 - - - - ko00000,ko01000 - - - ERAP1_C,Peptidase_M1 k141_35251_2 218284.CCDN010000002_gene1990 7.04e-133 385.0 COG0150@1|root,COG0150@2|Bacteria,1TP9J@1239|Firmicutes,4HABW@91061|Bacilli,1ZBPS@1386|Bacillus 91061|Bacilli F Phosphoribosylformylglycinamidine cyclo-ligase purM - 6.3.3.1 ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04208 RC01100 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C k141_18670_1 1385517.N800_06235 7.1e-119 348.0 COG0491@1|root,COG0491@2|Bacteria,1P5NJ@1224|Proteobacteria,1S1CZ@1236|Gammaproteobacteria,1X6Q6@135614|Xanthomonadales 135614|Xanthomonadales S Metallo-beta-lactamase superfamily - - 3.5.2.6 ko:K17837 ko01501,map01501 - R06363 RC01499 ko00000,ko00001,ko01000 - - - Lactamase_B k141_22057_1 1347369.CCAD010000048_gene253 3.17e-20 83.2 COG1826@1|root,COG1826@2|Bacteria,1VFP2@1239|Firmicutes,4HNM7@91061|Bacilli,1ZIUG@1386|Bacillus 91061|Bacilli U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system tatA - - ko:K03116 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - MttA_Hcf106 k141_22057_2 1294265.JCM21738_455 2.66e-60 189.0 COG0437@1|root,COG0437@2|Bacteria 2|Bacteria C 4 iron, 4 sulfur cluster binding - - 1.5.5.1 ko:K00311 - - - - ko00000,ko01000 - - - CCG,Fer4,Fer4_8,NrfD k141_23420_1 218284.CCDN010000001_gene190 2.5e-231 655.0 COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,4HA3G@91061|Bacilli,1ZAVY@1386|Bacillus 91061|Bacilli T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,PAS_4,PAS_9 k141_1760_1 1116375.VEJY3_14540 8.22e-127 372.0 COG5002@1|root,COG5002@2|Bacteria,1QUGI@1224|Proteobacteria,1T1Y9@1236|Gammaproteobacteria,1XT99@135623|Vibrionales 135623|Vibrionales T sensor protein cpxA - 2.7.13.3 ko:K07640 ko01503,ko02020,map01503,map02020 M00447,M00727,M00728 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - CpxA_peri,HAMP,HATPase_c,HisKA k141_5609_1 1236542.BALM01000043_gene454 1.82e-24 100.0 COG0657@1|root,COG0657@2|Bacteria,1NEXK@1224|Proteobacteria,1RYVV@1236|Gammaproteobacteria,2Q9IG@267890|Shewanellaceae 1236|Gammaproteobacteria I PFAM Alpha beta hydrolase fold-3 domain protein - - - ko:K01066 - - - - ko00000,ko01000 - - - Abhydrolase_3,PNP_UDP_1 k141_5609_2 1042377.AFPJ01000038_gene1099 8.68e-08 53.1 COG0591@1|root,COG0642@1|root,COG0784@1|root,COG0591@2|Bacteria,COG0784@2|Bacteria,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,1RP2U@1236|Gammaproteobacteria,465DY@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0591 Na proline symporter - - - - - - - - - - - - HATPase_c,HisKA,PAS_7,Response_reg,SSF k141_12795_1 42565.FP66_15945 1.61e-45 154.0 COG1218@1|root,COG1218@2|Bacteria,1N0GY@1224|Proteobacteria,1RP5A@1236|Gammaproteobacteria,1XJKB@135619|Oceanospirillales 135619|Oceanospirillales P nucleotidase cysQ - 3.1.3.7 ko:K01082 ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130 - R00188,R00508 RC00078 ko00000,ko00001,ko01000,ko03016 - - - Inositol_P k141_12795_2 1178482.BJB45_10320 1.26e-52 181.0 COG0471@1|root,COG0490@1|root,COG0471@2|Bacteria,COG0490@2|Bacteria,1MU0K@1224|Proteobacteria,1RMI1@1236|Gammaproteobacteria,1XHSW@135619|Oceanospirillales 135619|Oceanospirillales P COG0471 Di- and tricarboxylate transporters - - - - - - - - - - - - CitMHS,Na_sulph_symp,TrkA_C k141_17308_1 1034347.CAHJ01000021_gene3364 5.03e-25 102.0 COG0477@1|root,COG2814@2|Bacteria,1U72T@1239|Firmicutes,4HCHH@91061|Bacilli,1ZCHP@1386|Bacillus 91061|Bacilli EGP COG0477 Permeases of the major facilitator superfamily ykuC - - - - - - - - - - - MFS_1 k141_10369_1 236097.ADG881_789 1.02e-69 212.0 COG1733@1|root,COG1733@2|Bacteria,1RIZT@1224|Proteobacteria,1S5HB@1236|Gammaproteobacteria,1XPDZ@135619|Oceanospirillales 135619|Oceanospirillales K Transcriptional regulators - - - - - - - - - - - - HxlR k141_10369_2 1453501.JELR01000002_gene800 6.84e-63 202.0 COG1902@1|root,COG1902@2|Bacteria,1MVIX@1224|Proteobacteria,1RMFI@1236|Gammaproteobacteria,464MK@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family - - - - - - - - - - - - Oxidored_FMN k141_27150_2 1453501.JELR01000002_gene1026 1.68e-265 728.0 COG3185@1|root,COG3185@2|Bacteria,1MUVZ@1224|Proteobacteria,1RN2Z@1236|Gammaproteobacteria,465EP@72275|Alteromonadaceae 1236|Gammaproteobacteria E 4-hydroxyphenylpyruvate dioxygenase hppD - 1.13.11.27 ko:K00457 ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100 M00044 R01372,R02521 RC00505,RC00738 ko00000,ko00001,ko00002,ko01000,ko04147 - - iJN746.PP_3433 Glyoxalase,Glyoxalase_5 k141_36215_1 205918.Psyr_4865 2.34e-35 133.0 COG0687@1|root,COG0687@2|Bacteria,1MUYW@1224|Proteobacteria,1RM7W@1236|Gammaproteobacteria,1Z66Y@136849|Pseudomonas syringae group 1236|Gammaproteobacteria P COG0687 Spermidine putrescine-binding periplasmic protein potF1 - - ko:K11073 ko02010,map02010 M00300 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.2 - - SBP_bac_8 k141_4257_2 1042377.AFPJ01000036_gene1263 1.5e-67 211.0 2C4GG@1|root,331DQ@2|Bacteria,1N7QC@1224|Proteobacteria,1SCI3@1236|Gammaproteobacteria,468SZ@72275|Alteromonadaceae 1236|Gammaproteobacteria S Polyribonucleotide nucleotidyltransferase - - - - - - - - - - - - - k141_32671_3 1455075.W6PPI5_9CAUD 1.67e-16 83.6 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QNG7@10744|Podoviridae 10744|Podoviridae S lytic transglycosylase activity - GO:0008150,GO:0016032,GO:0019058,GO:0030260,GO:0039678,GO:0044403,GO:0044409,GO:0044411,GO:0044419,GO:0046718,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0051830,GO:0085027 - - - - - - - - - - - k141_32671_16 10658.DPOL_BPPRD 3.2e-153 458.0 4QAWD@10239|Viruses,4QVNG@35237|dsDNA viruses no RNA stage,4QHTW@10656|Tectiviridae 10656|Tectiviridae L DNA binding - GO:0003674,GO:0003824,GO:0003887,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576 - - - - - - - - - - - k141_25820_1 1336233.JAEH01000024_gene1130 1.64e-86 275.0 COG1512@1|root,COG1512@2|Bacteria,1QUWH@1224|Proteobacteria,1T23P@1236|Gammaproteobacteria,2QAD5@267890|Shewanellaceae 1236|Gammaproteobacteria S PFAM Peptidase M9A, collagenase - - 3.4.24.3 ko:K01387 - - - - ko00000,ko01000,ko01002,ko02042 - - - PPC,Peptidase_M9,Peptidase_M9_N k141_16146_1 84531.JMTZ01000001_gene2228 0.000289 46.6 COG1309@1|root,COG1309@2|Bacteria,1R8KS@1224|Proteobacteria,1S9ER@1236|Gammaproteobacteria,1X8V5@135614|Xanthomonadales 135614|Xanthomonadales K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N k141_16146_2 1089551.KE386572_gene363 6.3e-106 331.0 COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,2TU35@28211|Alphaproteobacteria 28211|Alphaproteobacteria P cytochrome c peroxidase mauG GO:0005575,GO:0005623,GO:0042597,GO:0044464 - - - - - - - - - - CCP_MauG,Cytochrom_C k141_18703_1 634956.Geoth_1193 6.46e-32 117.0 COG1671@1|root,COG1671@2|Bacteria,1V9Z0@1239|Firmicutes,4HM1G@91061|Bacilli,1WGAD@129337|Geobacillus 91061|Bacilli S Belongs to the UPF0178 family yqxD - - ko:K09768 - - - - ko00000 - - - DUF188 k141_6717_1 1121920.AUAU01000033_gene2764 4.97e-83 262.0 COG1418@1|root,COG1418@2|Bacteria 2|Bacteria S mRNA catabolic process rny - - ko:K18682 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - DUF3552,HD,KH_1 k141_2997_1 1034347.CAHJ01000017_gene3460 3.79e-103 306.0 COG0407@1|root,COG0407@2|Bacteria,1TR8Q@1239|Firmicutes,4HAXT@91061|Bacilli,1ZDGX@1386|Bacillus 91061|Bacilli H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III hemE GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03197,R04972 RC00872 ko00000,ko00001,ko00002,ko01000 - - - URO-D k141_24497_1 981383.AEWH01000024_gene2629 1.89e-44 158.0 COG1190@1|root,COG1190@2|Bacteria,1UYMP@1239|Firmicutes,4HATI@91061|Bacilli 91061|Bacilli J tRNA synthetases class II (D, K and N) - - - - - - - - - - - - tRNA-synt_2 k141_14881_1 1137799.GZ78_18315 4.49e-15 74.3 COG2515@1|root,COG2515@2|Bacteria,1MVYF@1224|Proteobacteria,1RMYP@1236|Gammaproteobacteria,1XJ6V@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the alpha,beta-elimination reaction of D- cysteine and of several D-cysteine derivatives. It could be a defense mechanism against D-cysteine - - 3.5.99.7 ko:K01505 ko00270,map00270 - R00997 RC00419 ko00000,ko00001,ko01000 - - - PALP k141_14881_2 1279017.AQYJ01000025_gene763 6.34e-62 197.0 COG0061@1|root,COG0061@2|Bacteria,1MUBC@1224|Proteobacteria,1RP84@1236|Gammaproteobacteria,464AZ@72275|Alteromonadaceae 1236|Gammaproteobacteria H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP nadK GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 - R00104 RC00002,RC00078 ko00000,ko00001,ko01000 - - iEcSMS35_1347.EcSMS35_2767 NAD_kinase k141_30252_1 218284.CCDN010000001_gene1751 1.82e-147 424.0 COG0626@1|root,COG0626@2|Bacteria,1TPC7@1239|Firmicutes,4HAFQ@91061|Bacilli,1ZAR9@1386|Bacillus 91061|Bacilli E cystathionine metC GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0016740,GO:0016765,GO:0016829,GO:0016846 4.4.1.8 ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU11880 Cys_Met_Meta_PP k141_18704_1 1294265.JCM21738_2050 6.71e-09 55.1 COG0006@1|root,COG0006@2|Bacteria,1TQ44@1239|Firmicutes,4HAT7@91061|Bacilli,1ZB4P@1386|Bacillus 91061|Bacilli E COG0006 Xaa-Pro aminopeptidase yqhT - 3.4.11.9 ko:K01262 - - - - ko00000,ko01000,ko01002 - - - Creatinase_N,Peptidase_M24 k141_18704_2 1294265.JCM21738_2051 2.42e-95 278.0 COG0757@1|root,COG0757@2|Bacteria,1V6E8@1239|Firmicutes,4HJ2V@91061|Bacilli,1ZG8H@1386|Bacillus 91061|Bacilli E Catalyzes a trans-dehydration via an enolate intermediate aroQ - 4.2.1.10 ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03084 RC00848 ko00000,ko00001,ko00002,ko01000 - - - DHquinase_II k141_24498_1 985665.HPL003_13975 8.26e-76 236.0 COG1089@1|root,COG1089@2|Bacteria,1TQ9T@1239|Firmicutes,4HB2M@91061|Bacilli,26S2Z@186822|Paenibacillaceae 91061|Bacilli M Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose gmd - 4.2.1.47 ko:K01711 ko00051,ko00520,ko01100,map00051,map00520,map01100 - R00888 RC00402 ko00000,ko00001,ko01000 - - - GDP_Man_Dehyd k141_22087_1 1279017.AQYJ01000026_gene240 8.73e-201 560.0 COG2974@1|root,COG2974@2|Bacteria,1MXPR@1224|Proteobacteria,1RMNN@1236|Gammaproteobacteria,4650K@72275|Alteromonadaceae 1236|Gammaproteobacteria L May be involved in recombination rdgC GO:0000018,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009295,GO:0019219,GO:0019222,GO:0031323,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363 - ko:K03554 - - - - ko00000,ko03400 - - - RdgC k141_22087_2 1265503.KB905166_gene939 6.17e-25 100.0 COG2819@1|root,COG2819@2|Bacteria,1RB1X@1224|Proteobacteria,1RY80@1236|Gammaproteobacteria,2Q86H@267889|Colwelliaceae 1236|Gammaproteobacteria S Putative esterase - - - ko:K07017 - - - - ko00000 - - - Esterase k141_7763_1 648757.Rvan_3160 7.59e-62 201.0 COG2801@1|root,COG2801@2|Bacteria,1MVQ9@1224|Proteobacteria,2TTHG@28211|Alphaproteobacteria,3N7C9@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria L PFAM Integrase catalytic region - - - - - - - - - - - - rve,rve_3 k141_6718_2 1453501.JELR01000002_gene983 2.66e-34 129.0 COG0699@1|root,COG0699@2|Bacteria,1MXBK@1224|Proteobacteria,1RSJC@1236|Gammaproteobacteria,465QM@72275|Alteromonadaceae 1236|Gammaproteobacteria S GTPases (dynamin-related) - - - - - - - - - - - - Dynamin_N k141_30253_1 1123236.KB899388_gene2104 2.46e-114 329.0 COG0807@1|root,COG0807@2|Bacteria,1MWZR@1224|Proteobacteria,1RMFX@1236|Gammaproteobacteria,465AE@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate ribA GO:0003674,GO:0003824,GO:0003933,GO:0003935,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019238,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.5.4.25 ko:K01497 ko00740,ko00790,ko01100,ko01110,ko02024,map00740,map00790,map01100,map01110,map02024 M00125 R00425 RC00293,RC02504 ko00000,ko00001,ko00002,ko01000 - - - DUF1768,GTP_cyclohydro2 k141_14882_2 583345.Mmol_2218 2.82e-38 147.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,2KM6C@206350|Nitrosomonadales 206350|Nitrosomonadales V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran k141_23435_1 981384.AEYW01000012_gene1050 2.54e-135 392.0 COG1638@1|root,COG1638@2|Bacteria,1R5WY@1224|Proteobacteria,2TVHA@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Bacterial extracellular solute-binding protein, family 7 - - - - - - - - - - - - DctP k141_23435_2 314256.OG2516_17665 5.24e-34 124.0 COG4665@1|root,COG4665@2|Bacteria,1N1QB@1224|Proteobacteria,2UKCB@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q Tripartite ATP-independent periplasmic transporters, DctQ component - - - - - - - - - - - - DctQ k141_23435_3 981384.AEYW01000012_gene1048 2.05e-207 585.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2TQW5@28211|Alphaproteobacteria,4NBI7@97050|Ruegeria 28211|Alphaproteobacteria G hmm pf06808 - - - - - - - - - - - - DctM k141_23435_5 1267533.KB906741_gene653 5.95e-29 107.0 COG4274@1|root,COG4274@2|Bacteria,3Y87J@57723|Acidobacteria 57723|Acidobacteria S GYD domain - - - - - - - - - - - - GYD k141_23435_6 1278307.KB907034_gene571 1.11e-112 327.0 COG0110@1|root,COG0110@2|Bacteria,1RA2T@1224|Proteobacteria,1S3ZZ@1236|Gammaproteobacteria,2QIG8@267894|Psychromonadaceae 1236|Gammaproteobacteria S Maltose acetyltransferase lacA - 2.3.1.18,2.3.1.79 ko:K00633,ko:K00661 - - - - ko00000,ko01000 - - - Hexapep,Hexapep_2,Mac k141_23435_7 1238450.VIBNISOn1_900015 1.06e-26 100.0 COG0789@1|root,COG0789@2|Bacteria,1N9D2@1224|Proteobacteria,1SBR8@1236|Gammaproteobacteria,1XYA6@135623|Vibrionales 135623|Vibrionales K Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - - - - - - - - - - MerR_1 k141_14013_1 1499680.CCFE01000023_gene2433 5.06e-49 166.0 COG1105@1|root,COG1105@2|Bacteria,1TQ36@1239|Firmicutes,4HANU@91061|Bacilli,1ZB76@1386|Bacillus 91061|Bacilli G Belongs to the carbohydrate kinase PfkB family pfkB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046835,GO:0071704 2.7.1.56 ko:K00882 ko00051,map00051 - R02071 RC00002,RC00017 ko00000,ko00001,ko01000 - - iYO844.BSU14390 PfkB k141_14013_2 218284.CCDN010000005_gene3493 1.65e-136 392.0 COG1349@1|root,COG1349@2|Bacteria,1TSF8@1239|Firmicutes,4HDT9@91061|Bacilli,1ZBIR@1386|Bacillus 91061|Bacilli K Transcriptional regulator fruR - - ko:K03436 - - - - ko00000,ko03000 - - - DeoRC,HTH_DeoR k141_18706_1 218284.CCDN010000001_gene1518 5.58e-61 196.0 COG1388@1|root,COG3584@1|root,COG1388@2|Bacteria,COG3584@2|Bacteria,1UV4J@1239|Firmicutes,4HCGU@91061|Bacilli,1ZFSM@1386|Bacillus 91061|Bacilli M COG1388 FOG LysM repeat yocH - - - - - - - - - - - 3D,LysM k141_20832_1 1198114.AciX9_3035 9.09e-50 173.0 COG0334@1|root,COG0334@2|Bacteria,3Y3B4@57723|Acidobacteria,2JI4Q@204432|Acidobacteriia 204432|Acidobacteriia E Belongs to the Glu Leu Phe Val dehydrogenases family - - 1.4.1.3 ko:K00261 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 M00740 R00243,R00248 RC00006,RC02799 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ELFV_dehydrog,ELFV_dehydrog_N k141_5611_1 1042163.BRLA_c021840 4.74e-37 134.0 COG0631@1|root,COG0631@2|Bacteria,1V8SI@1239|Firmicutes,4HJEG@91061|Bacilli,26V6G@186822|Paenibacillaceae 91061|Bacilli T Protein phosphatase 2C - - - - - - - - - - - - PP2C_2 k141_5611_2 1123405.AUMM01000029_gene1560 5.03e-57 184.0 COG0241@1|root,COG0241@2|Bacteria,1V6DW@1239|Firmicutes,4HJ23@91061|Bacilli 91061|Bacilli E HAD-hyrolase-like - - - - - - - - - - - - Hydrolase_like k141_5611_3 935837.JAEK01000057_gene2478 4.36e-83 253.0 COG1011@1|root,COG1011@2|Bacteria,1TWM7@1239|Firmicutes,4HEXU@91061|Bacilli,1ZRIV@1386|Bacillus 91061|Bacilli S HAD-hyrolase-like yfnB - 3.8.1.2 ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 - R05287 RC00697 ko00000,ko00001,ko01000 - - - HAD_2 k141_36217_1 999141.GME_13615 1.15e-101 300.0 COG1291@1|root,COG1291@2|Bacteria,1R7XA@1224|Proteobacteria,1SY9W@1236|Gammaproteobacteria,1XIFR@135619|Oceanospirillales 135619|Oceanospirillales N MotA/TolQ/ExbB proton channel family - - - - - - - - - - - - MotA_ExbB k141_9116_1 1191299.AJYX01000097_gene1669 2e-52 174.0 COG3508@1|root,COG3508@2|Bacteria,1MV9G@1224|Proteobacteria,1RQG2@1236|Gammaproteobacteria,1XTK2@135623|Vibrionales 135623|Vibrionales Q COG3508 Homogentisate 1,2-dioxygenase - GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0055114 1.13.11.5 ko:K00451 ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120 M00044 R02519 RC00737 ko00000,ko00001,ko00002,ko01000 - - - HgmA k141_9116_2 1116375.VEJY3_06490 1.76e-257 706.0 COG3185@1|root,COG3185@2|Bacteria,1MUVZ@1224|Proteobacteria,1RN2Z@1236|Gammaproteobacteria,1XSAG@135623|Vibrionales 135623|Vibrionales C COG3185 4-hydroxyphenylpyruvate dioxygenase and related hemolysins hppD - 1.13.11.27 ko:K00457 ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100 M00044 R01372,R02521 RC00505,RC00738 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Glyoxalase,Glyoxalase_5 k141_9116_3 1280001.BAOA01000196_gene4299 1.1e-185 521.0 COG2195@1|root,COG2195@2|Bacteria,1MV7D@1224|Proteobacteria,1TH92@1236|Gammaproteobacteria,1XSN9@135623|Vibrionales 135623|Vibrionales E COG2195 Di- and tripeptidases - - 3.4.11.4 ko:K01258 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20,Peptidase_M28 k141_14014_1 1294265.JCM21738_488 6.56e-93 283.0 COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,4HA6M@91061|Bacilli,1ZB9G@1386|Bacillus 91061|Bacilli J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family rumA_1 - 2.1.1.190,2.1.1.35 ko:K00557,ko:K03215 - - - - ko00000,ko01000,ko03009,ko03016 - - - TRAM,tRNA_U5-meth_tr k141_27895_1 525365.HMPREF0548_0842 3.59e-11 65.1 COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,4HAWN@91061|Bacilli,3F3JW@33958|Lactobacillaceae 91061|Bacilli L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) recG - 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecG_wedge k141_27895_2 760568.Desku_1720 4.75e-23 97.4 COG0836@1|root,COG0836@2|Bacteria,1TPC9@1239|Firmicutes,24908@186801|Clostridia,2613M@186807|Peptococcaceae 186801|Clostridia M TIGRFAM mannose-1-phosphate guanylyltransferase mannose-6-phosphate isomerase manC - 2.7.7.13 ko:K00971 ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110 M00114,M00361,M00362 R00885 RC00002 ko00000,ko00001,ko00002,ko01000 - - - MannoseP_isomer,NTP_transferase k141_23738_1 1453501.JELR01000002_gene710 2.28e-104 314.0 COG2885@1|root,COG2885@2|Bacteria,1RCNJ@1224|Proteobacteria,1S2JT@1236|Gammaproteobacteria,46CJ1@72275|Alteromonadaceae 1236|Gammaproteobacteria M Bacterial protein of unknown function (DUF937) oprF - - ko:K03286 - - - - ko00000,ko02000 1.B.6 - - DUF937,OMP_b-brl,OmpA,OprF,TSP_3 k141_1032_1 218284.CCDN010000002_gene2037 2.04e-189 531.0 COG0477@1|root,COG2814@2|Bacteria,1TQHD@1239|Firmicutes,4HBCZ@91061|Bacilli,1ZDDG@1386|Bacillus 91061|Bacilli EGP COG0477 Permeases of the major facilitator superfamily - - - - - - - - - - - - MFS_1,Sugar_tr k141_5753_1 218284.CCDN010000002_gene2120 2.54e-204 568.0 COG0059@1|root,COG0059@2|Bacteria,1TPI7@1239|Firmicutes,4HADK@91061|Bacilli,1ZCH5@1386|Bacillus 91061|Bacilli EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate ilvC - 1.1.1.86 ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R03051,R04439,R04440,R05068,R05069,R05071 RC00726,RC00836,RC00837,RC01726 ko00000,ko00001,ko00002,ko01000 - - - IlvC,IlvN k141_6999_2 218284.CCDN010000002_gene2194 8.98e-104 305.0 COG5012@1|root,COG5012@2|Bacteria,1V5DK@1239|Firmicutes,4HJ9Z@91061|Bacilli,1ZFGI@1386|Bacillus 91061|Bacilli S B12 binding domain - - - - - - - - - - - - B12-binding,B12-binding_2 k141_28011_1 1116375.VEJY3_18296 6.81e-106 327.0 COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,1RNKA@1236|Gammaproteobacteria 1236|Gammaproteobacteria H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses nadE - 6.3.1.5,6.3.5.1 ko:K01916,ko:K01950 ko00760,ko01100,map00760,map01100 M00115 R00189,R00257 RC00010,RC00100 ko00000,ko00001,ko00002,ko01000 - - - CN_hydrolase,NAD_synthase k141_32908_2 1279017.AQYJ01000021_gene2913 1.26e-57 192.0 COG1823@1|root,COG1823@2|Bacteria,1R3F8@1224|Proteobacteria,1RMHV@1236|Gammaproteobacteria,465XI@72275|Alteromonadaceae 1236|Gammaproteobacteria U Sodium:dicarboxylate symporter family ydjN GO:0000099,GO:0000101,GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006791,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015184,GO:0015318,GO:0015711,GO:0015804,GO:0015807,GO:0015811,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072337,GO:0072348,GO:0072349,GO:0098656,GO:1901682,GO:1902475,GO:1903825,GO:1905039 - ko:K06956 - - - - ko00000 - - - SDF k141_10462_2 1116375.VEJY3_00950 1.04e-58 189.0 COG1560@1|root,COG1560@2|Bacteria,1N9ZJ@1224|Proteobacteria,1RRI7@1236|Gammaproteobacteria,1XTMN@135623|Vibrionales 135623|Vibrionales M Catalyzes the transfer of myristate from myristoyl-acyl carrier protein (ACP) to Kdo(2)-(lauroyl)-lipid IV(A) to form Kdo(2)-lipid A lpxM - 2.3.1.243 ko:K02560 ko00540,ko01100,map00540,map01100 M00060 R05075 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Lip_A_acyltrans k141_23739_1 1268072.PSAB_08880 9.11e-44 155.0 COG2038@1|root,COG2038@2|Bacteria,1TPC1@1239|Firmicutes,4HAE0@91061|Bacilli,26RX1@186822|Paenibacillaceae 91061|Bacilli H Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) cobT - 2.4.2.21 ko:K00768 ko00860,ko01100,map00860,map01100 M00122 R04148 RC00033,RC00063 ko00000,ko00001,ko00002,ko01000 - - - DBI_PRT k141_35478_1 190486.XAC4227 1.8e-84 270.0 COG3661@1|root,COG3661@2|Bacteria,1MXKA@1224|Proteobacteria,1RP0V@1236|Gammaproteobacteria,1X5RV@135614|Xanthomonadales 135614|Xanthomonadales G Belongs to the glycosyl hydrolase 67 family aguA - 3.2.1.139 ko:K01235 - - - - ko00000,ko01000 - - - Glyco_hydro_67C,Glyco_hydro_67M,Glyco_hydro_67N k141_35478_2 1453501.JELR01000005_gene1637 5.03e-16 77.0 COG1629@1|root,COG1629@2|Bacteria,1MV8W@1224|Proteobacteria,1RQEQ@1236|Gammaproteobacteria,463XU@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec k141_36379_1 420246.GTNG_1303 2.07e-55 180.0 COG0572@1|root,COG0572@2|Bacteria,1V4T0@1239|Firmicutes,4HHU2@91061|Bacilli,1WGGR@129337|Geobacillus 91061|Bacilli F Phosphoribulokinase / Uridine kinase family - - 2.7.1.48 ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PRK k141_1034_1 121225.PHUM411080-PA 1.29e-37 141.0 COG2355@1|root,KOG4127@2759|Eukaryota,38D9H@33154|Opisthokonta,3BCAM@33208|Metazoa,3CRIG@33213|Bilateria,41UQH@6656|Arthropoda,3SIVJ@50557|Insecta,3ECS6@33342|Paraneoptera 33208|Metazoa O Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family - GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0016787,GO:0016805,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.13.19 ko:K01273 - - - - ko00000,ko00537,ko01000,ko01002,ko04147 - - - Peptidase_M19 k141_37600_1 218284.CCDN010000001_gene154 2.08e-144 412.0 COG0022@1|root,COG0022@2|Bacteria,1TP3J@1239|Firmicutes,4HA4H@91061|Bacilli,1ZBJ1@1386|Bacillus 91061|Bacilli C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit pdhB - 1.2.4.1 ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS05355,iYO844.BSU14590 Transket_pyr,Transketolase_C k141_7000_1 1122194.AUHU01000003_gene2075 5.16e-36 131.0 COG1597@1|root,COG1597@2|Bacteria,1MY37@1224|Proteobacteria,1RMX9@1236|Gammaproteobacteria,46CFQ@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - - - - - - - - - - DAGK_cat k141_7000_2 1122194.AUHU01000003_gene2076 5.55e-29 110.0 2EM7P@1|root,33EWT@2|Bacteria,1NJGG@1224|Proteobacteria,1SGVR@1236|Gammaproteobacteria,46CC6@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_5754_1 1111454.HMPREF1250_1890 3e-08 60.5 COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,4H2A8@909932|Negativicutes 909932|Negativicutes C glutamate synthase (NADPH) gltA - 1.4.1.13,1.4.1.14 ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - DHODB_Fe-S_bind,Fer4_20,NADH_4Fe-4S,NAD_binding_1,Pyr_redox_2 k141_1035_1 218284.CCDN010000008_gene4037 4.17e-96 280.0 28T9W@1|root,2ZFIH@2|Bacteria,1V1JV@1239|Firmicutes,4HFXV@91061|Bacilli,1ZGK3@1386|Bacillus 91061|Bacilli K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization hutP GO:0006082,GO:0006355,GO:0006520,GO:0006547,GO:0006548,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016054,GO:0019219,GO:0019222,GO:0019439,GO:0019752,GO:0031323,GO:0031326,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0052803,GO:0052805,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1903506,GO:2000112,GO:2001141 - ko:K09683 - - - - ko00000,ko03000 - - - HutP k141_11763_1 1123228.AUIH01000024_gene3288 2.13e-85 266.0 COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,1RP0C@1236|Gammaproteobacteria,1XHQT@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - - - - - - - - - - Aminotran_3 k141_23740_1 1279017.AQYJ01000020_gene1261 2.74e-139 400.0 COG1902@1|root,COG1902@2|Bacteria,1MVIX@1224|Proteobacteria,1RMFI@1236|Gammaproteobacteria,464MK@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family - - - - - - - - - - - - Oxidored_FMN k141_9395_1 218284.CCDN010000001_gene528 5.07e-68 213.0 COG0266@1|root,COG0266@2|Bacteria,1TPM9@1239|Firmicutes,4H9Q7@91061|Bacilli,1ZCC9@1386|Bacillus 91061|Bacilli L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates fpg - 3.2.2.23,4.2.99.18 ko:K10563 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Fapy_DNA_glyco,H2TH,zf-FPG_IleRS k141_24713_1 1042377.AFPJ01000012_gene1380 7.02e-25 100.0 2AEBT@1|root,31468@2|Bacteria,1RC39@1224|Proteobacteria,1S7QQ@1236|Gammaproteobacteria,468QT@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_24713_3 717774.Marme_0177 2.88e-12 63.9 COG3529@1|root,COG3529@2|Bacteria,1NC40@1224|Proteobacteria,1SEJF@1236|Gammaproteobacteria,1XS9W@135619|Oceanospirillales 135619|Oceanospirillales S Probable metal-binding protein (DUF2387) - - - ko:K07070 - - - - ko00000 - - - DUF2387 k141_24713_4 1453501.JELR01000002_gene1080 0.0 969.0 COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,1RMAH@1236|Gammaproteobacteria,4648F@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0339 Zn-dependent oligopeptidases prlC GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006465,GO:0006508,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0034645,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051604,GO:0070011,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564,GO:1901576 3.4.24.70 ko:K01414 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M3 k141_11764_1 1042377.AFPJ01000030_gene497 9.69e-55 179.0 COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,1RMBM@1236|Gammaproteobacteria,464U3@72275|Alteromonadaceae 1236|Gammaproteobacteria G Catalyzes the NAD-dependent conversion of D-erythrose 4- phosphate to 4-phosphoerythronate gapA - 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N k141_36380_1 42565.FP66_12765 2.9e-85 259.0 COG0568@1|root,COG0568@2|Bacteria,1MUDI@1224|Proteobacteria,1RN8V@1236|Gammaproteobacteria,1XHDS@135619|Oceanospirillales 135619|Oceanospirillales K RNA polymerase sigma factor RpoS rpoS - - ko:K03087 ko02026,ko05111,map02026,map05111 - - - ko00000,ko00001,ko03021 - - - Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 k141_29383_1 218284.CCDN010000008_gene4139 8.39e-194 546.0 COG3547@1|root,COG3547@2|Bacteria,1V427@1239|Firmicutes,4HGY6@91061|Bacilli,1ZERT@1386|Bacillus 91061|Bacilli L PFAM transposase IS116 IS110 IS902 family - - - - - - - - - - - - DEDD_Tnp_IS110,Transposase_20 k141_20965_1 218284.CCDN010000008_gene4137 1.22e-145 432.0 COG0058@1|root,COG0058@2|Bacteria,1TQAJ@1239|Firmicutes,4H9XI@91061|Bacilli,1ZCRF@1386|Bacillus 91061|Bacilli G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties glgP GO:0000272,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005976,GO:0005977,GO:0005980,GO:0006073,GO:0006091,GO:0006112,GO:0008144,GO:0008150,GO:0008152,GO:0008184,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0015980,GO:0016052,GO:0016740,GO:0016757,GO:0016758,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901575 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 - R02111 - ko00000,ko00001,ko01000 - GT35 iYO844.BSU30940 Phosphorylase k141_20965_2 218284.CCDN010000008_gene4136 5.05e-97 294.0 COG0297@1|root,COG0297@2|Bacteria,1TQ4M@1239|Firmicutes,4HAVA@91061|Bacilli,1ZDBA@1386|Bacillus 91061|Bacilli G Synthesizes alpha-1,4-glucan chains using ADP-glucose glgA GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009011,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 M00565 R02421 RC00005 ko00000,ko00001,ko00002,ko01000,ko01003 - GT5 - Glyco_transf_5,Glycos_transf_1 k141_30380_3 260799.BAS1410 5.77e-09 53.1 2EHPS@1|root,33BFI@2|Bacteria,1VM1E@1239|Firmicutes,4HS3S@91061|Bacilli,1ZK03@1386|Bacillus 91061|Bacilli S YpzI-like protein - - - - - - - - - - - - YpzI k141_23741_1 1279017.AQYJ01000025_gene701 1.04e-105 333.0 COG2887@1|root,COG2887@2|Bacteria,1QVX1@1224|Proteobacteria,1RP9I@1236|Gammaproteobacteria,465DQ@72275|Alteromonadaceae 1236|Gammaproteobacteria L PD-(D/E)XK nuclease superfamily lidB - - - - - - - - - - - PDDEXK_1 k141_5755_1 1034347.CAHJ01000015_gene3167 1.52e-111 327.0 COG0437@1|root,COG0437@2|Bacteria,1V35R@1239|Firmicutes,4HVW5@91061|Bacilli,1ZSG7@1386|Bacillus 91061|Bacilli C 4Fe-4S dicluster domain - - - - - - - - - - - - Fer4_11 k141_37601_2 218284.CCDN010000001_gene703 5.94e-23 92.8 COG0500@1|root,COG2226@2|Bacteria,1V3T6@1239|Firmicutes,4HHF1@91061|Bacilli,1ZFN7@1386|Bacillus 91061|Bacilli Q Could be a S-adenosyl-L-methionine-dependent methyltransferase yrrT GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 - ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 M00609 R10404 RC00003 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_11,Methyltransf_23,Methyltransf_25 k141_1036_1 314287.GB2207_00240 5.02e-55 182.0 COG0604@1|root,COG0604@2|Bacteria,1MWRK@1224|Proteobacteria,1SYCA@1236|Gammaproteobacteria 1236|Gammaproteobacteria C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases qor - 1.6.5.5 ko:K00344 - - - - ko00000,ko01000 - - - ADH_N,ADH_zinc_N k141_26029_2 223926.28808653 2.34e-69 211.0 2AX0J@1|root,31NYK@2|Bacteria,1QKMX@1224|Proteobacteria,1TISE@1236|Gammaproteobacteria,1XZJQ@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_26029_3 1116375.VEJY3_22126 1.86e-205 608.0 COG0493@1|root,COG3383@1|root,COG0493@2|Bacteria,COG3383@2|Bacteria,1MU2H@1224|Proteobacteria,1SMV9@1236|Gammaproteobacteria,1Y32S@135623|Vibrionales 135623|Vibrionales C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - 1.17.1.9 ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001,ko01000 - - - Fer2_4,Fer4,Fer4_20,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,Pyr_redox_2 k141_10463_1 1042377.AFPJ01000037_gene3000 1.65e-114 334.0 COG0101@1|root,COG0101@2|Bacteria,1MUYI@1224|Proteobacteria,1RMK2@1236|Gammaproteobacteria,464DE@72275|Alteromonadaceae 1236|Gammaproteobacteria J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs truA GO:0000049,GO:0001522,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 5.4.99.12 ko:K06173 - - - - ko00000,ko01000,ko03016 - - - PseudoU_synth_1 k141_9397_1 218284.CCDN010000005_gene3226 2.91e-73 224.0 COG1670@1|root,COG1670@2|Bacteria,1V8EU@1239|Firmicutes,4HJPX@91061|Bacilli,1ZQWF@1386|Bacillus 91061|Bacilli J Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_3 k141_9397_2 218284.CCDN010000005_gene3227 4.17e-09 58.5 COG0477@1|root,COG2814@2|Bacteria,1UXYG@1239|Firmicutes,4HBZB@91061|Bacilli,1ZQ79@1386|Bacillus 91061|Bacilli EGP COG0477 Permeases of the major facilitator superfamily ynfM3 - - - - - - - - - - - MFS_1,Sugar_tr k141_22399_1 1116375.VEJY3_03050 2.68e-281 803.0 COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,1RMRN@1236|Gammaproteobacteria,1XTXA@135623|Vibrionales 135623|Vibrionales F Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate purL GO:0003674,GO:0003824,GO:0004642,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - AIRS_C,GATase_5 k141_22399_2 223926.28805651 0.0 919.0 COG4623@1|root,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,1RM8W@1236|Gammaproteobacteria,1XTC4@135623|Vibrionales 135623|Vibrionales M Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella mltF GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009253,GO:0009279,GO:0016020,GO:0019867,GO:0030203,GO:0030312,GO:0030313,GO:0031975,GO:0043170,GO:0044462,GO:0044464,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - ko:K18691 - - - - ko00000,ko01000,ko01011 - - - SBP_bac_3,SLT k141_22399_3 1116375.VEJY3_03040 6.74e-104 302.0 COG0590@1|root,COG0590@2|Bacteria,1RGU0@1224|Proteobacteria,1S60Z@1236|Gammaproteobacteria,1XUA6@135623|Vibrionales 135623|Vibrionales FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) tadA - 3.5.4.33 ko:K11991 - - R10223 RC00477 ko00000,ko01000,ko03016 - - - MafB19-deam k141_22399_4 1280001.BAOA01000038_gene4373 3.68e-154 445.0 COG2978@1|root,COG2978@2|Bacteria,1MUJ1@1224|Proteobacteria,1RMAI@1236|Gammaproteobacteria,1XSAR@135623|Vibrionales 135623|Vibrionales H p-aminobenzoyl-glutamate transporter abgT - - - - - - - - - - - ABG_transport k141_5756_1 1294265.JCM21738_3018 1.02e-116 337.0 COG0217@1|root,COG0217@2|Bacteria,1TPP5@1239|Firmicutes,4H9WJ@91061|Bacilli,1ZBN0@1386|Bacillus 91061|Bacilli K transcriptional regulatory protein yeeN GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - - - - - - - - - - Transcrip_reg k141_23743_1 1274524.BSONL12_04574 8.4e-26 98.6 2DYNB@1|root,34AF5@2|Bacteria,1TZKM@1239|Firmicutes,4I8VS@91061|Bacilli,1ZIFS@1386|Bacillus 91061|Bacilli S Helix-turn-helix of insertion element transposase - - - - - - - - - - - - HTH_Tnp_1_2 k141_11766_1 1034347.CAHJ01000057_gene835 4.64e-146 426.0 COG0823@1|root,COG0823@2|Bacteria,1UZMN@1239|Firmicutes,4HBYS@91061|Bacilli,1ZEJZ@1386|Bacillus 91061|Bacilli U Involved in the tonB-independent uptake of proteins - - - - - - - - - - - - PD40 k141_7003_1 218284.CCDN010000007_gene3854 5.31e-220 609.0 COG0642@1|root,COG0642@2|Bacteria,1TQSG@1239|Firmicutes,4ISJC@91061|Bacilli,1ZS73@1386|Bacillus 91061|Bacilli T Signal transduction histidine kinase bceS - 2.7.13.3 ko:K11629 ko02020,map02020 M00469,M00738 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c k141_7003_2 218284.CCDN010000007_gene3855 1.53e-92 274.0 COG0745@1|root,COG0745@2|Bacteria,1TR32@1239|Firmicutes,4HAUJ@91061|Bacilli,1ZCP0@1386|Bacillus 91061|Bacilli T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain graR - - ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 M00469,M00725,M00726,M00730,M00733,M00738 - - ko00000,ko00001,ko00002,ko01504,ko02022 - - - Response_reg,Trans_reg_C k141_29386_1 1453501.JELR01000002_gene1048 9.71e-33 122.0 COG0454@1|root,COG0456@2|Bacteria,1MVZ2@1224|Proteobacteria,1RSC5@1236|Gammaproteobacteria,465P6@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG0456 Acetyltransferases - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10,DUF3335 k141_29386_2 1453501.JELR01000002_gene1049 3.63e-102 312.0 COG2234@1|root,COG2234@2|Bacteria,1MUZ7@1224|Proteobacteria,1RS0Q@1236|Gammaproteobacteria,4653N@72275|Alteromonadaceae 1236|Gammaproteobacteria S PA domain - - - - - - - - - - - - PA,Peptidase_M28 k141_22400_1 1196031.ALEG01000034_gene5331 3.3e-28 111.0 COG0614@1|root,COG0614@2|Bacteria,1UNE3@1239|Firmicutes,4H9ZX@91061|Bacilli,1ZBS8@1386|Bacillus 91061|Bacilli P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component yvrC - - ko:K02016 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - Peripla_BP_2 k141_24715_1 1453501.JELR01000001_gene1803 1.33e-79 240.0 2E01C@1|root,32VQM@2|Bacteria,1N20N@1224|Proteobacteria,1SACC@1236|Gammaproteobacteria,46C3Y@72275|Alteromonadaceae 1236|Gammaproteobacteria S YcxB-like protein VPA0798 - - - - - - - - - - - YcxB k141_37602_1 218284.CCDN010000002_gene2090 2.07e-125 360.0 COG1024@1|root,COG1024@2|Bacteria,1TQ2V@1239|Firmicutes,4HBT0@91061|Bacilli,1ZE3C@1386|Bacillus 91061|Bacilli I Belongs to the enoyl-CoA hydratase isomerase family paaG - 5.3.3.18 ko:K15866 ko00360,ko01120,map00360,map01120 - R09837,R09839 RC00004,RC00326,RC02689,RC03003 ko00000,ko00001,ko01000 - - - ECH_1 k141_4395_1 1279017.AQYJ01000026_gene33 5.88e-256 711.0 28HNB@1|root,2Z7WM@2|Bacteria,1MWQ1@1224|Proteobacteria,1RZ55@1236|Gammaproteobacteria,464IB@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_4395_2 1279017.AQYJ01000026_gene34 1.29e-27 100.0 2EK1G@1|root,33DRY@2|Bacteria,1NH6C@1224|Proteobacteria,1SGMZ@1236|Gammaproteobacteria,468WX@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF3012) - - - - - - - - - - - - DUF3012 k141_4395_3 1279017.AQYJ01000026_gene35 2.43e-294 809.0 COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,1RP5K@1236|Gammaproteobacteria,464RP@72275|Alteromonadaceae 1236|Gammaproteobacteria J Belongs to the class-I aminoacyl-tRNA synthetase family cysS - 6.1.1.16 ko:K01883 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_2,tRNA-synt_1e,tRNA-synt_1g k141_23744_1 1294265.JCM21738_3256 1.13e-100 295.0 COG3576@1|root,COG3576@2|Bacteria,1UZ02@1239|Firmicutes,4HEN8@91061|Bacilli,1ZC4B@1386|Bacillus 91061|Bacilli S Pyridoxamine 5'-phosphate oxidase - - - ko:K07006 - - - - ko00000 - - - Putative_PNPOx k141_32913_1 240302.BN982_03149 4.95e-66 217.0 COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,4HA09@91061|Bacilli 91061|Bacilli K Transcriptional lytR - - - - - - - - - - - LytR_cpsA_psr k141_35505_1 218284.CCDN010000001_gene1368 1.03e-84 258.0 COG0477@1|root,COG2814@2|Bacteria,1UN0M@1239|Firmicutes,4HBBP@91061|Bacilli,1ZD0U@1386|Bacillus 91061|Bacilli EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 k141_20004_1 218284.CCDN010000001_gene1585 1.59e-59 191.0 COG2367@1|root,COG2367@2|Bacteria,1UYZ3@1239|Firmicutes,4IPX7@91061|Bacilli,1ZPVE@1386|Bacillus 91061|Bacilli V Beta-lactamase enzyme family - - - - - - - - - - - - Beta-lactamase2 k141_29409_1 1453501.JELR01000001_gene2672 1.42e-81 245.0 COG1739@1|root,COG1739@2|Bacteria,1NFJC@1224|Proteobacteria,1RPBF@1236|Gammaproteobacteria,4672X@72275|Alteromonadaceae 1236|Gammaproteobacteria S Uncharacterized protein family UPF0029 yigZ - 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 - - - DUF1949,UPF0029 k141_17413_1 1042377.AFPJ01000051_gene56 2.62e-98 290.0 COG0576@1|root,COG0576@2|Bacteria,1RH8T@1224|Proteobacteria,1S5W5@1236|Gammaproteobacteria,467BX@72275|Alteromonadaceae 1236|Gammaproteobacteria O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ grpE GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0017076,GO:0019904,GO:0022607,GO:0030234,GO:0030554,GO:0032991,GO:0036094,GO:0042802,GO:0042803,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0050790,GO:0050896,GO:0051082,GO:0060589,GO:0060590,GO:0065003,GO:0065007,GO:0065009,GO:0071840,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - ko:K03687 - - - - ko00000,ko03029,ko03110 - - - GrpE k141_23766_1 290317.Cpha266_0325 1.33e-30 121.0 COG5421@1|root,COG5421@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - DDE_Tnp_1 k141_3233_1 1042377.AFPJ01000037_gene2860 3.77e-43 144.0 COG3086@1|root,COG3086@2|Bacteria,1N6QS@1224|Proteobacteria,1SCTM@1236|Gammaproteobacteria,468GR@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG3086 Positive regulator of sigma E activity rseC GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0016020,GO:0044464,GO:0050896,GO:0071944 - ko:K03803 - - - - ko00000,ko03021 - - - RseC_MucC k141_3233_2 1453501.JELR01000001_gene1981 1.34e-45 157.0 COG3026@1|root,COG3026@2|Bacteria,1MUQ8@1224|Proteobacteria,1RNF3@1236|Gammaproteobacteria,467RQ@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG3026 Negative regulator of sigma E activity rseB GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0044464,GO:0045152 - ko:K03598 - - - - ko00000,ko03021 - - - MucB_RseB,MucB_RseB_C k141_1958_1 1304888.ATWF01000002_gene475 3.37e-42 158.0 COG0747@1|root,COG0747@2|Bacteria,2GEIN@200930|Deferribacteres 200930|Deferribacteres E Peptide nickel ABC transporter, substrate-binding protein - - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 k141_1958_2 644076.SCH4B_2894 2.36e-06 49.3 COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2TRH6@28211|Alphaproteobacteria,4NBRM@97050|Ruegeria 28211|Alphaproteobacteria P hmm pf00528 - - - ko:K02033 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 k141_37623_2 265729.GS18_0210000 1.7e-73 226.0 COG1595@1|root,COG1595@2|Bacteria,1VTV0@1239|Firmicutes,4HTC4@91061|Bacilli,1ZFY2@1386|Bacillus 91061|Bacilli K Belongs to the sigma-70 factor family. ECF subfamily sigY - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_16345_1 218284.CCDN010000002_gene2942 6.48e-72 227.0 COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,4HBED@91061|Bacilli,1ZBXY@1386|Bacillus 91061|Bacilli EP COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components dppB - - ko:K02033 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 k141_34227_1 1168289.AJKI01000010_gene1607 1.98e-27 113.0 COG3250@1|root,COG3250@2|Bacteria,4NF3W@976|Bacteroidetes,2FM0P@200643|Bacteroidia,3XJUX@558415|Marinilabiliaceae 976|Bacteroidetes G Beta galactosidase small chain - - 3.2.1.23 ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 - R01105,R01678,R03355,R04783,R06114 RC00049,RC00452 ko00000,ko00001,ko01000 - - - Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N k141_29410_1 1294265.JCM21738_423 4.55e-194 542.0 COG4585@1|root,COG4585@2|Bacteria,1TQI3@1239|Firmicutes,4HAUU@91061|Bacilli,1ZH6W@1386|Bacillus 91061|Bacilli T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA_3,PAS,PAS_8 k141_35506_1 218284.CCDN010000001_gene1223 1.07e-30 108.0 28VRR@1|root,2ZHTJ@2|Bacteria,1W6RM@1239|Firmicutes,4IFAF@91061|Bacilli,1ZITN@1386|Bacillus 91061|Bacilli S YozD-like protein yozD - - - - - - - - - - - YozD k141_7036_1 42565.FP66_06480 2.82e-114 347.0 COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,1RNSZ@1236|Gammaproteobacteria,1XH4H@135619|Oceanospirillales 135619|Oceanospirillales J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome fusA - - ko:K02355 - - - - ko00000,ko03012,ko03029 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 k141_20983_1 1333507.AUTQ01000073_gene2087 2.47e-40 142.0 COG2267@1|root,COG2267@2|Bacteria,1N0W6@1224|Proteobacteria,1S931@1236|Gammaproteobacteria 1236|Gammaproteobacteria I carboxylic ester hydrolase activity - - - - - - - - - - - - Abhydrolase_6,Hydrolase_4 k141_11802_1 1279017.AQYJ01000020_gene1350 2.96e-22 96.3 2DBQ1@1|root,2ZABN@2|Bacteria,1R83J@1224|Proteobacteria,1T169@1236|Gammaproteobacteria,46BUW@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_36406_1 218284.CCDN010000001_gene165 3.88e-163 471.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,1ZASV@1386|Bacillus 91061|Bacilli V COG1132 ABC-type multidrug transport system, ATPase and permease components yknU GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702 - ko:K06147,ko:K11085 ko02010,map02010 - - - ko00000,ko00001,ko01000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran k141_35507_1 218284.CCDN010000008_gene4151 3.09e-88 268.0 COG0803@1|root,COG0803@2|Bacteria,1TPG7@1239|Firmicutes,4H9UN@91061|Bacilli,1ZC2Z@1386|Bacillus 91061|Bacilli P Belongs to the bacterial solute-binding protein 9 family adcA - - ko:K09815,ko:K09818 ko02010,map02010 M00242,M00243 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 - - ZnuA k141_28040_1 1042377.AFPJ01000009_gene196 7.68e-25 95.9 COG2923@1|root,COG2923@2|Bacteria,1N8RV@1224|Proteobacteria,1SD0S@1236|Gammaproteobacteria,468RD@72275|Alteromonadaceae 1236|Gammaproteobacteria P DsrE/DsrF-like family tusC GO:0002097,GO:0002098,GO:0002143,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1902494,GO:1990228,GO:1990234 - ko:K07236 ko04122,map04122 - - - ko00000,ko00001,ko03016 - - - DrsE k141_28040_2 1279017.AQYJ01000029_gene3741 6.81e-33 116.0 COG2168@1|root,COG2168@2|Bacteria,1NGF3@1224|Proteobacteria,1SGPI@1236|Gammaproteobacteria,468W2@72275|Alteromonadaceae 1236|Gammaproteobacteria P DsrH like protein tusB GO:0002097,GO:0002098,GO:0002143,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1902494,GO:1990228,GO:1990234 - ko:K07237 ko04122,map04122 - - - ko00000,ko00001,ko03016 - - - DsrH k141_28040_3 1453501.JELR01000001_gene2207 1.57e-43 143.0 COG2920@1|root,COG2920@2|Bacteria,1RGVG@1224|Proteobacteria,1S5ZA@1236|Gammaproteobacteria,467QI@72275|Alteromonadaceae 1236|Gammaproteobacteria P Part of a sulfur-relay system tusE GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097163,GO:0140104,GO:1901360 - ko:K11179 ko04122,map04122 - - - ko00000,ko00001,ko01000,ko03016 - - - DsrC k141_9426_1 218284.CCDN010000007_gene4027 1.2e-79 239.0 2E3V2@1|root,32YSB@2|Bacteria,1V8K8@1239|Firmicutes,4HMGU@91061|Bacilli,1ZEV0@1386|Bacillus 91061|Bacilli S YwpF-like protein ywpF - - - - - - - - - - - YwpF k141_7037_1 1453501.JELR01000002_gene1205 2.14e-71 235.0 COG1404@1|root,COG5640@1|root,COG1404@2|Bacteria,COG5640@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria,464PM@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG1404 Subtilisin-like serine proteases - GO:0005575,GO:0005576 - ko:K14645 ko02024,map02024 - - - ko00000,ko00001,ko01000,ko01002,ko03110 - - - PKD,PPC,P_proprotein,Peptidase_S8 k141_31551_1 1122194.AUHU01000006_gene646 4.27e-10 60.5 COG1472@1|root,COG1472@2|Bacteria,1MVIV@1224|Proteobacteria,1RMA0@1236|Gammaproteobacteria,465BV@72275|Alteromonadaceae 1236|Gammaproteobacteria G Family 3 - - 3.2.1.21 ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 - R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - GH3 - Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C k141_11804_2 1123371.ATXH01000033_gene422 7.95e-52 180.0 COG0151@1|root,COG0151@2|Bacteria,2GGTX@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria F Belongs to the GARS family purD - 6.3.4.13 ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144 RC00090,RC00166 ko00000,ko00001,ko00002,ko01000 - - - AIRC,GARS_A,GARS_C,GARS_N k141_36683_1 1453501.JELR01000001_gene3031 1.08e-89 281.0 COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,465W3@72275|Alteromonadaceae 1236|Gammaproteobacteria T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - GAF_2,HAMP,HATPase_c,HisKA,Hpt,NMT1,PAS,PAS_3,PAS_4,PAS_9,Response_reg k141_36684_1 1042377.AFPJ01000019_gene2533 3.73e-60 199.0 COG4242@1|root,COG4242@2|Bacteria,1PR9J@1224|Proteobacteria,1RVJH@1236|Gammaproteobacteria,469D6@72275|Alteromonadaceae 1236|Gammaproteobacteria PQ Peptidase family S51 cphB - 3.4.15.6 ko:K13282 - - R09722 RC00064,RC00141 ko00000,ko01000,ko01002 - - - Peptidase_S51 k141_30658_1 589865.DaAHT2_1207 1.23e-23 100.0 COG0632@1|root,COG0632@2|Bacteria,1MWJR@1224|Proteobacteria,42RPS@68525|delta/epsilon subdivisions,2WPH5@28221|Deltaproteobacteria,2MPUQ@213118|Desulfobacterales 28221|Deltaproteobacteria L RuvA, C-terminal domain ruvA - 3.6.4.12 ko:K03550 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - HHH_5,RuvA_C,RuvA_N k141_37969_1 218284.CCDN010000001_gene686 6.52e-70 215.0 COG1268@1|root,COG1268@2|Bacteria,1TS7R@1239|Firmicutes,4HC1H@91061|Bacilli,1ZCIP@1386|Bacillus 91061|Bacilli S Biotin biosynthesis protein bioY - - ko:K03523 ko02010,map02010 M00581,M00582 - - ko00000,ko00001,ko00002,ko02000 2.A.88.1,2.A.88.2 - - BioY k141_37969_2 218284.CCDN010000001_gene685 1.34e-79 258.0 COG0507@1|root,COG0507@2|Bacteria,1TPZH@1239|Firmicutes,4HATQ@91061|Bacilli,1ZAYS@1386|Bacillus 91061|Bacilli L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity recD2 - 3.1.11.5 ko:K03581 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_30,HHH_4,HHH_5,UvrD_C_2 k141_8190_1 1453501.JELR01000002_gene763 3.42e-303 850.0 COG0834@1|root,COG4623@1|root,COG0834@2|Bacteria,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,1RM8W@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella - GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - ko:K18691 - - - - ko00000,ko01000,ko01011 - - - SBP_bac_3,SLT k141_8190_3 1279017.AQYJ01000026_gene401 4.6e-99 310.0 COG1651@1|root,COG1651@2|Bacteria 2|Bacteria O Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - 5.3.4.1 ko:K03981 - - - - ko00000,ko01000,ko02044,ko03110 3.A.7.11.1 - - DSBA,Thioredoxin_2,Thioredoxin_4 k141_28430_1 745411.B3C1_09797 9.27e-21 102.0 COG1506@1|root,COG1506@2|Bacteria,1MUJ3@1224|Proteobacteria,1RPAW@1236|Gammaproteobacteria,1J6JZ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases - - 3.4.19.1 ko:K01303 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S9 k141_36685_1 1169144.KB910988_gene2751 5.94e-118 343.0 COG3409@1|root,COG3773@1|root,COG3409@2|Bacteria,COG3773@2|Bacteria,1TRFW@1239|Firmicutes,4HA2V@91061|Bacilli,1ZB40@1386|Bacillus 91061|Bacilli M Spore cortex-lytic enzyme sleB GO:0005575,GO:0005623,GO:0042763,GO:0044464 3.5.1.28 ko:K01449 - - R04112 RC00064,RC00141 ko00000,ko01000 - - - Hydrolase_2,PG_binding_1 k141_37971_1 1216007.AOPM01000101_gene688 5.53e-66 224.0 COG1629@1|root,COG1629@2|Bacteria,1MVSG@1224|Proteobacteria,1RS33@1236|Gammaproteobacteria,2Q1RF@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria P Carboxypeptidase regulatory-like domain - - - - - - - - - - - - CarboxypepD_reg k141_28431_1 218284.CCDN010000005_gene3339 1.42e-24 94.7 COG1764@1|root,COG1764@2|Bacteria,1V41Y@1239|Firmicutes,4HH9W@91061|Bacilli,1ZFXM@1386|Bacillus 91061|Bacilli O redox protein, regulator of disulfide bond formation ymaD - - - - - - - - - - - OsmC k141_36687_1 1305836.AXVE01000011_gene1018 5.84e-132 385.0 COG3459@1|root,COG3459@2|Bacteria,1TQY8@1239|Firmicutes,4HBZV@91061|Bacilli,26GM9@186818|Planococcaceae 91061|Bacilli G Protein of unknown function (DUF3131) - - - - - - - - - - - - DUF3131,Glycoamylase k141_8193_1 218284.CCDN010000001_gene462 2.8e-130 373.0 COG0588@1|root,COG0588@2|Bacteria,1TQFP@1239|Firmicutes,4HAW7@91061|Bacilli,1ZE2V@1386|Bacillus 91061|Bacilli G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate gpmA GO:0001871,GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009986,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030246,GO:0030247,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031,GO:2001065 5.4.2.11 ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - His_Phos_1 k141_36688_1 1453501.JELR01000001_gene2487 1.24e-78 237.0 2C1GI@1|root,33B43@2|Bacteria,1NJE7@1224|Proteobacteria,1SH3D@1236|Gammaproteobacteria,468W3@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_8194_1 1279009.ADICEAN_00697 2.93e-42 144.0 2BINM@1|root,32CVS@2|Bacteria,4PC76@976|Bacteroidetes,47WZA@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - k141_30660_1 997296.PB1_05752 1.65e-121 362.0 COG2304@1|root,COG2304@2|Bacteria,1TQHE@1239|Firmicutes,4HBUG@91061|Bacilli,1ZQU2@1386|Bacillus 91061|Bacilli S von Willebrand factor (vWF) type A domain - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - VWA,VWA_2 k141_36689_1 218284.CCDN010000001_gene112 7.95e-58 179.0 COG4471@1|root,COG4471@2|Bacteria,1VF52@1239|Firmicutes,4HNTH@91061|Bacilli,1ZI4I@1386|Bacillus 91061|Bacilli S UPF0298 protein ylbG - - - - - - - - - - - DUF2129 k141_36689_2 218284.CCDN010000001_gene111 9.99e-67 204.0 2CC47@1|root,2ZQ3T@2|Bacteria,1V53R@1239|Firmicutes,4HIC8@91061|Bacilli,1ZGZC@1386|Bacillus 91061|Bacilli S Methylthioribose kinase - - - - - - - - - - - - - k141_28434_1 1131730.BAVI_17682 1.22e-26 103.0 COG0745@1|root,COG0745@2|Bacteria,1TSWT@1239|Firmicutes,4HBSC@91061|Bacilli,1ZCSV@1386|Bacillus 91061|Bacilli T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain hssR - - ko:K02483 - - - - ko00000,ko02022 - - - Response_reg,Trans_reg_C k141_28434_2 1002809.SSIL_2435 3.13e-104 316.0 COG3850@1|root,COG5002@1|root,COG3850@2|Bacteria,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4IS5F@91061|Bacilli,26IHB@186818|Planococcaceae 91061|Bacilli T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain hssS - 2.7.13.3 ko:K02484 - - - - ko00000,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA k141_8196_2 218284.CCDN010000012_gene4440 3.71e-136 386.0 COG1428@1|root,COG1428@2|Bacteria,1TPJ1@1239|Firmicutes,4HA9N@91061|Bacilli,1ZBFB@1386|Bacillus 91061|Bacilli F Deoxycytidine kinase dck - 2.7.1.74,2.7.1.76 ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 - R00185,R01666,R02089 RC00002,RC00017 ko00000,ko00001,ko01000 - - - dNK k141_36691_1 1279017.AQYJ01000028_gene2079 1.46e-119 366.0 COG2755@1|root,COG2755@2|Bacteria,1MXTS@1224|Proteobacteria,1RTPH@1236|Gammaproteobacteria,46419@72275|Alteromonadaceae 1236|Gammaproteobacteria E Concanavalin A-like lectin/glucanases superfamily - - - - - - - - - - - - Laminin_G_3 k141_37978_1 221109.22775916 1.29e-60 192.0 COG1404@1|root,COG1404@2|Bacteria,1VIHE@1239|Firmicutes,4HPPJ@91061|Bacilli 91061|Bacilli O Peptidase inhibitor I9 - - - - - - - - - - - - Inhibitor_I9 k141_30663_2 218284.CCDN010000001_gene1415 5.53e-11 59.7 COG2149@1|root,COG2149@2|Bacteria,1VEBE@1239|Firmicutes,4HP6Q@91061|Bacilli,1ZIBU@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF202) - - - ko:K00389 - - - - ko00000 - - - DUF202 k141_21387_1 1078085.HMPREF1210_00996 2.73e-19 81.6 COG3832@1|root,COG3832@2|Bacteria,1V7US@1239|Firmicutes,4HK0E@91061|Bacilli,26FBZ@186818|Planococcaceae 91061|Bacilli S Activator of Hsp90 ATPase homolog 1-like protein yndB - - - - - - - - - - - AHSA1 k141_21387_2 1347086.CCBA010000023_gene2371 2.26e-58 182.0 COG0640@1|root,COG0640@2|Bacteria,1VA4S@1239|Firmicutes,4HKBK@91061|Bacilli,1ZHGM@1386|Bacillus 91061|Bacilli K helix_turn_helix, Arsenical Resistance Operon Repressor - - - - - - - - - - - - HTH_20,HTH_5 k141_21387_3 279010.BL00480 6.12e-64 209.0 28IH1@1|root,2Z8IC@2|Bacteria,1TSE5@1239|Firmicutes,4HD81@91061|Bacilli,1ZDYE@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF4003) yeaA - - - - - - - - - - - DUF4003 k141_30664_1 218284.CCDN010000001_gene1292 1.2e-50 171.0 COG0454@1|root,COG0456@2|Bacteria,1V4T1@1239|Firmicutes,4HDYC@91061|Bacilli,1ZDHN@1386|Bacillus 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10 k141_31797_2 1453501.JELR01000001_gene3032 2.69e-241 667.0 COG1398@1|root,COG1398@2|Bacteria,1N2MA@1224|Proteobacteria,1RM88@1236|Gammaproteobacteria,465C3@72275|Alteromonadaceae 1236|Gammaproteobacteria I desaturase desC - 1.14.19.1 ko:K00507 ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212 - R02222 RC00917 ko00000,ko00001,ko01000,ko01004 - - - FA_desaturase k141_31797_3 1279017.AQYJ01000023_gene3124 3.48e-277 781.0 COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,465W3@72275|Alteromonadaceae 1236|Gammaproteobacteria T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - GAF_2,HAMP,HATPase_c,HisKA,Hpt,NMT1,PAS,PAS_3,PAS_4,PAS_9,Response_reg k141_30665_1 316274.Haur_4762 3.93e-48 166.0 COG1027@1|root,COG1027@2|Bacteria,2G5IV@200795|Chloroflexi,37644@32061|Chloroflexia 32061|Chloroflexia C PFAM fumarate lyase - - 4.2.1.2 ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 M00009,M00011,M00173,M00376 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - - FumaraseC_C,Lyase_1 k141_28435_1 218284.CCDN010000009_gene4277 4.64e-90 280.0 COG0449@1|root,COG0449@2|Bacteria,1TPGU@1239|Firmicutes,4H9R4@91061|Bacilli,1ZBI5@1386|Bacillus 91061|Bacilli M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source glmS GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 - R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 - - iSB619.SA_RS11245,iYO844.BSU01780 GATase_6,SIS k141_31798_1 218284.CCDN010000005_gene3445 3.17e-112 335.0 COG0651@1|root,COG0651@2|Bacteria,1TRAT@1239|Firmicutes,4HA10@91061|Bacilli,1ZB2A@1386|Bacillus 91061|Bacilli CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali mrpD GO:0003674,GO:0005215,GO:0005451,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015491,GO:0015672,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0035725,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0098655,GO:0098660,GO:0098662,GO:0099516,GO:1902600 - ko:K05568 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - iSB619.SA_RS04615 Proton_antipo_M k141_15349_2 1116375.VEJY3_22346 5.74e-147 420.0 COG1266@1|root,COG1266@2|Bacteria,1P0IE@1224|Proteobacteria,1RS9M@1236|Gammaproteobacteria,1XV8N@135623|Vibrionales 135623|Vibrionales S CAAX protease self-immunity - - - ko:K07052 - - - - ko00000 - - - Abi k141_15349_3 1116375.VEJY3_22341 3.36e-187 522.0 COG0115@1|root,COG0115@2|Bacteria,1MVAT@1224|Proteobacteria,1RPU0@1236|Gammaproteobacteria,1XYS3@135623|Vibrionales 135623|Vibrionales EH Amino-transferase class IV - - 2.6.1.21 ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 - R01148,R01582,R02459,R02851,R02924,R05053 RC00006,RC00008,RC00025 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_4 k141_15349_4 1116375.VEJY3_22336 3.92e-59 191.0 COG4948@1|root,COG4948@2|Bacteria,1MW76@1224|Proteobacteria,1RMKS@1236|Gammaproteobacteria,1XUBP@135623|Vibrionales 135623|Vibrionales M Belongs to the mandelate racemase muconate lactonizing enzyme family - - 5.1.1.20 ko:K19802 - - R10938 RC03309 ko00000,ko01000 - - - MR_MLE_C,MR_MLE_N k141_37980_1 218284.CCDN010000003_gene2963 6.41e-111 323.0 COG0125@1|root,COG0125@2|Bacteria,1V1HE@1239|Firmicutes,4HGWR@91061|Bacilli,1ZBSZ@1386|Bacillus 91061|Bacilli F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis tmk GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 ko:K00943 ko00240,ko01100,map00240,map01100 M00053 R02094,R02098 RC00002 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS02535 Thymidylate_kin k141_37980_2 97139.C824_05657 3.01e-06 51.2 COG1982@1|root,COG1982@2|Bacteria,1TNZ9@1239|Firmicutes,247RA@186801|Clostridia,36DPH@31979|Clostridiaceae 186801|Clostridia E Orn Lys Arg decarboxylase major speA - 4.1.1.19 ko:K01585 ko00330,ko01100,map00330,map01100 M00133 R00566 RC00299 ko00000,ko00001,ko00002,ko01000 - - - OKR_DC_1,OKR_DC_1_C k141_21391_2 1453501.JELR01000001_gene2222 7.01e-14 70.5 COG0416@1|root,COG0416@2|Bacteria,1MVM3@1224|Proteobacteria,1RM7R@1236|Gammaproteobacteria,464HB@72275|Alteromonadaceae 1236|Gammaproteobacteria I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA plsX GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0071704,GO:0090407,GO:1901576 2.3.1.15 ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - iEcDH1_1363.EcDH1_2557,iSFxv_1172.SFxv_1246,iY75_1357.Y75_RS05695 FA_synthesis k141_15350_1 1408303.JNJJ01000143_gene846 1.4e-55 187.0 29SI9@1|root,30DPE@2|Bacteria,1UBHF@1239|Firmicutes,4IMWS@91061|Bacilli,1ZM1M@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_36692_1 1042377.AFPJ01000009_gene307 4.1e-204 581.0 COG2866@1|root,COG2866@2|Bacteria,1R6VU@1224|Proteobacteria,1S14Z@1236|Gammaproteobacteria,466N8@72275|Alteromonadaceae 1236|Gammaproteobacteria E Zinc carboxypeptidase - - - - - - - - - - - - Peptidase_M14 k141_36692_2 1279017.AQYJ01000029_gene3476 1.22e-88 264.0 COG2356@1|root,COG2356@2|Bacteria,1RI3H@1224|Proteobacteria,1S6A9@1236|Gammaproteobacteria,4681D@72275|Alteromonadaceae 1236|Gammaproteobacteria L Protein of unknown function (DUF1524) - - - - - - - - - - - - DUF1524 k141_36693_1 1340434.AXVA01000007_gene5149 1.66e-69 219.0 COG2064@1|root,COG2064@2|Bacteria,1V2T1@1239|Firmicutes,4IRDA@91061|Bacilli,1ZR4J@1386|Bacillus 91061|Bacilli NU Type II secretion system (T2SS), protein F - - - - - - - - - - - - T2SSF k141_28437_1 1078085.HMPREF1210_02147 5.46e-94 312.0 COG1404@1|root,COG1404@2|Bacteria,1TPH1@1239|Firmicutes,4HBQH@91061|Bacilli 91061|Bacilli O Belongs to the peptidase S8 family prtS - 3.4.21.110,3.4.21.96 ko:K01361,ko:K08652 - - - - ko00000,ko01000,ko01002,ko03110 - - - FIVAR,Gram_pos_anchor,Inhibitor_I9,PA,Peptidase_S8,SLH,YSIRK_signal,fn3_5 k141_36694_1 1122138.AQUZ01000011_gene5011 7.27e-24 103.0 COG0399@1|root,COG0399@2|Bacteria,2GKD7@201174|Actinobacteria,4DPCW@85009|Propionibacteriales 201174|Actinobacteria E Belongs to the DegT DnrJ EryC1 family degT - - - - - - - - - - - DegT_DnrJ_EryC1 k141_31800_1 218284.CCDN010000002_gene2915 1.58e-203 575.0 COG0661@1|root,COG0661@2|Bacteria,1TPIV@1239|Firmicutes,4HBW3@91061|Bacilli,1ZBPH@1386|Bacillus 91061|Bacilli S ABC1 family ubiB - - - - - - - - - - - ABC1,APH,RIO1 k141_30669_1 1294265.JCM21738_1368 5.89e-166 469.0 COG1252@1|root,COG1252@2|Bacteria,1TPE6@1239|Firmicutes,4H9MY@91061|Bacilli,1ZC0V@1386|Bacillus 91061|Bacilli C NADH dehydrogenase yutJ - 1.6.99.3 ko:K03885 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - Pyr_redox_2 k141_8307_1 218284.CCDN010000001_gene683 1.55e-185 520.0 COG0482@1|root,COG0482@2|Bacteria,1TPIZ@1239|Firmicutes,4HBJ6@91061|Bacilli,1ZBWQ@1386|Bacillus 91061|Bacilli J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 mnmA GO:0002097,GO:0002098,GO:0002143,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 2.8.1.13 ko:K00566 ko04122,map04122 - R08700 RC02313,RC02315 ko00000,ko00001,ko01000,ko03016 - - - tRNA_Me_trans k141_30786_1 42565.FP66_12975 4.26e-105 330.0 COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,1RMDS@1236|Gammaproteobacteria,1XHTN@135619|Oceanospirillales 135619|Oceanospirillales J Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs rne - 3.1.26.12 ko:K08300 ko03018,map03018 M00394 - - ko00000,ko00001,ko00002,ko01000,ko03009,ko03019 - - - RNase_E_G,S1 k141_8308_1 1246484.D479_03678 1.49e-69 218.0 COG0120@1|root,COG0120@2|Bacteria,1V1DB@1239|Firmicutes,4HFQ7@91061|Bacilli,3NDMT@45667|Halobacillus 91061|Bacilli G Ribose 5-phosphate isomerase A (phosphoriboisomerase A) rpiA - 5.3.1.6 ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167,M00580 R01056 RC00434 ko00000,ko00001,ko00002,ko01000 - - - Rib_5-P_isom_A k141_15419_2 1122134.KB893650_gene1285 2.75e-29 110.0 COG4257@1|root,COG4257@2|Bacteria,1QR8W@1224|Proteobacteria,1RQM4@1236|Gammaproteobacteria,1XPTW@135619|Oceanospirillales 135619|Oceanospirillales V Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid - - - - - - - - - - - - - k141_31888_1 1453501.JELR01000002_gene691 3.4e-100 298.0 COG3751@1|root,COG3751@2|Bacteria,1RD3H@1224|Proteobacteria,1S40I@1236|Gammaproteobacteria,46712@72275|Alteromonadaceae 1236|Gammaproteobacteria O 2OG-Fe(II) oxygenase - - - ko:K07394 - - - - ko00000 - - - 2OG-FeII_Oxy_3 k141_31888_4 1453501.JELR01000002_gene687 0.0 1227.0 COG3605@1|root,COG3605@2|Bacteria,1QTTV@1224|Proteobacteria,1T1H2@1236|Gammaproteobacteria,464IT@72275|Alteromonadaceae 1236|Gammaproteobacteria T Belongs to the PEP-utilizing enzyme family ptsP GO:0003674,GO:0003824,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008965,GO:0009987,GO:0010033,GO:0010243,GO:0016310,GO:0016740,GO:0016772,GO:0016775,GO:0019538,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050896,GO:0071704,GO:1901564,GO:1901698 2.7.3.9 ko:K08484 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 - - - GAF,GAF_2,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C k141_31888_5 1279017.AQYJ01000028_gene2170 1.2e-123 356.0 COG1051@1|root,COG1051@2|Bacteria,1QU0T@1224|Proteobacteria,1T1KA@1236|Gammaproteobacteria,46D92@72275|Alteromonadaceae 1236|Gammaproteobacteria F Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage nudH GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019222,GO:0019439,GO:0034353,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 - ko:K08311 ko03018,map03018 - R10816 RC00002 ko00000,ko00001,ko01000,ko03019 - - - NUDIX k141_31888_7 1279017.AQYJ01000028_gene2172 9.19e-154 446.0 COG3487@1|root,COG3487@2|Bacteria,1QTM3@1224|Proteobacteria,1RXQ2@1236|Gammaproteobacteria,468DH@72275|Alteromonadaceae 1236|Gammaproteobacteria P Imelysin - - - ko:K07231 - - - - ko00000 - - - Peptidase_M75 k141_31888_8 1279017.AQYJ01000028_gene2173 1.03e-99 292.0 COG3108@1|root,COG3108@2|Bacteria,1MWW2@1224|Proteobacteria,1RS5K@1236|Gammaproteobacteria,46B76@72275|Alteromonadaceae 1236|Gammaproteobacteria S Bacterial protein of unknown function (DUF882) ycbK - - - - - - - - - - - Peptidase_M15_2 k141_31888_9 1453501.JELR01000002_gene682 3.69e-73 233.0 COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,1RQR7@1236|Gammaproteobacteria,4668G@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria ycbB GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0006508,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0008236,GO:0008238,GO:0009273,GO:0009987,GO:0016740,GO:0016746,GO:0016755,GO:0016787,GO:0016807,GO:0017171,GO:0019538,GO:0033554,GO:0042546,GO:0043164,GO:0043170,GO:0044036,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0050896,GO:0051716,GO:0070004,GO:0070008,GO:0070011,GO:0071554,GO:0071704,GO:0071840,GO:0071972,GO:0140096,GO:1901564 - ko:K21470 - - - - ko00000,ko01002,ko01011 - - - PG_binding_1,YkuD k141_15421_1 1294265.JCM21738_4836 1.61e-68 216.0 2D8JG@1|root,32TRF@2|Bacteria,1VCDZ@1239|Firmicutes,4HMMY@91061|Bacilli,1ZFZF@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_31890_1 218284.CCDN010000001_gene1811 6.77e-103 304.0 COG2720@1|root,COG2720@2|Bacteria,1TSH8@1239|Firmicutes,4HCPD@91061|Bacilli,1ZBNK@1386|Bacillus 91061|Bacilli V vancomycin resistance protein yoaR - - - - - - - - - - - PG_binding_4,VanW k141_36765_1 1453501.JELR01000001_gene2593 9.68e-132 374.0 COG0450@1|root,COG0450@2|Bacteria,1MWPY@1224|Proteobacteria,1RN4S@1236|Gammaproteobacteria,4645P@72275|Alteromonadaceae 1236|Gammaproteobacteria O Alkyl hydroperoxide reductase ahpC GO:0003674,GO:0003824,GO:0004601,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009321,GO:0009605,GO:0009636,GO:0009970,GO:0009987,GO:0009991,GO:0010033,GO:0016209,GO:0016491,GO:0016667,GO:0016671,GO:0016684,GO:0019725,GO:0030003,GO:0031667,GO:0031668,GO:0031669,GO:0032843,GO:0032991,GO:0033194,GO:0033195,GO:0033212,GO:0033214,GO:0033554,GO:0042221,GO:0042592,GO:0042594,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071496,GO:0097237,GO:0098754,GO:0098771,GO:0098869,GO:1901700,GO:1902494,GO:1990204,GO:1990748 1.11.1.15 ko:K03386 ko04214,map04214 - - - ko00000,ko00001,ko01000,ko04147 - - - 1-cysPrx_C,AhpC-TSA k141_36765_2 1279017.AQYJ01000026_gene81 4.9e-171 494.0 COG4872@1|root,COG4872@2|Bacteria,1NAIX@1224|Proteobacteria,1S1XV@1236|Gammaproteobacteria,46ADY@72275|Alteromonadaceae 1236|Gammaproteobacteria S Predicted membrane protein (DUF2157) - - - - - - - - - - - - DUF2157 k141_36765_3 1279017.AQYJ01000026_gene80 2.37e-58 187.0 COG4929@1|root,COG4929@2|Bacteria,1NURJ@1224|Proteobacteria,1SBG7@1236|Gammaproteobacteria,46BI1@72275|Alteromonadaceae 1236|Gammaproteobacteria S GDYXXLXY protein - - - - - - - - - - - - GDYXXLXY k141_36765_4 1209072.ALBT01000046_gene2578 4.29e-32 122.0 COG1266@1|root,COG1266@2|Bacteria,1NIGX@1224|Proteobacteria,1TAMQ@1236|Gammaproteobacteria,1FIEJ@10|Cellvibrio 1236|Gammaproteobacteria S CAAX protease self-immunity - - - - - - - - - - - - Abi k141_36765_5 1042377.AFPJ01000016_gene118 1.14e-55 182.0 COG3932@1|root,COG3932@2|Bacteria,1N0FN@1224|Proteobacteria,1S4SJ@1236|Gammaproteobacteria,467N5@72275|Alteromonadaceae 1236|Gammaproteobacteria S ABC-type transport system, permease components - - - - - - - - - - - - ExoD k141_36765_6 983548.Krodi_1725 1.33e-18 89.4 COG2010@1|root,COG2010@2|Bacteria,4NIRV@976|Bacteroidetes,1HX5S@117743|Flavobacteriia 976|Bacteroidetes C Cytochrome c - - - - - - - - - - - - Cytochrom_C,DUF3365 k141_15422_2 477184.KYC_08315 9.11e-13 69.7 COG0609@1|root,COG0609@2|Bacteria,1MV9W@1224|Proteobacteria,2VN4K@28216|Betaproteobacteria,3T8XD@506|Alcaligenaceae 28216|Betaproteobacteria U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily - - - ko:K02015 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - FecCD k141_31891_1 502025.Hoch_1665 1.62e-42 145.0 2DMJS@1|root,32S1R@2|Bacteria,1R3IU@1224|Proteobacteria,43DUK@68525|delta/epsilon subdivisions,2WYX8@28221|Deltaproteobacteria,2Z0UM@29|Myxococcales 28221|Deltaproteobacteria S GXWXG protein - - - - - - - - - - - - DUF4334,GXWXG k141_30790_1 218284.CCDN010000005_gene3250 3.11e-185 516.0 COG3833@1|root,COG3833@2|Bacteria,1TRB7@1239|Firmicutes,4HC5K@91061|Bacilli,1ZB5C@1386|Bacillus 91061|Bacilli P transport malD GO:0003674,GO:0003824,GO:0005215,GO:0005363,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015154,GO:0015157,GO:0015399,GO:0015405,GO:0015422,GO:0015423,GO:0015766,GO:0015768,GO:0015772,GO:0015774,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0033037,GO:0034219,GO:0042623,GO:0042626,GO:0042956,GO:0043211,GO:0043492,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 - ko:K15772 ko02010,map02010 M00491 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.16,3.A.1.1.2 - - BPD_transp_1 k141_8313_1 218284.CCDN010000007_gene3814 6.33e-162 471.0 COG3887@1|root,COG3887@2|Bacteria,1TPGP@1239|Firmicutes,4HBVH@91061|Bacilli,1ZCB0@1386|Bacillus 91061|Bacilli T signaling protein consisting of a modified GGDEF domain and a DHH domain yybT - - - - - - - - - - - DHH,DHHA1 k141_31892_2 1121346.KB899843_gene1051 5.65e-24 98.2 COG0225@1|root,COG0229@1|root,COG0225@2|Bacteria,COG0229@2|Bacteria,1TQ3E@1239|Firmicutes,4HAIV@91061|Bacilli,26RB2@186822|Paenibacillaceae 91061|Bacilli O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine msrB - 1.8.4.11,1.8.4.12 ko:K12267 - - - - ko00000,ko01000 - - - PMSR,SelR k141_31893_1 218284.CCDN010000001_gene1884 6.14e-140 400.0 COG0196@1|root,COG0196@2|Bacteria,1TPKS@1239|Firmicutes,4H9KE@91061|Bacilli,1ZBFH@1386|Bacillus 91061|Bacilli H Belongs to the ribF family ribF - 2.7.1.26,2.7.7.2 ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS06310 FAD_syn,Flavokinase k141_15423_1 1415779.JOMH01000001_gene2595 1.25e-72 254.0 COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1MUKF@1224|Proteobacteria,1RMW6@1236|Gammaproteobacteria,1X47B@135614|Xanthomonadales 135614|Xanthomonadales S DNA internalization-related competence protein ComEC Rec2 comA - - ko:K02238 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - Competence,DUF4131,Lactamase_B k141_8316_1 796606.BMMGA3_08130 6.74e-26 102.0 COG3647@1|root,COG3647@2|Bacteria,1V19Q@1239|Firmicutes,4HB7P@91061|Bacilli,1ZG2Z@1386|Bacillus 91061|Bacilli S Predicted membrane protein (DUF2238) yjdF1 - - ko:K08984 - - - - ko00000 - - - DUF2238 k141_31894_1 1117379.BABA_00565 8.16e-118 347.0 COG3191@1|root,COG3191@2|Bacteria,1TQHA@1239|Firmicutes,4HAZM@91061|Bacilli,1ZDRB@1386|Bacillus 91061|Bacilli EQ Peptidase family S58 - - 3.4.11.19 ko:K01266 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S58 k141_31895_1 586413.CCDL010000001_gene614 1.41e-30 116.0 COG0673@1|root,COG0673@2|Bacteria,1USVA@1239|Firmicutes,4HDVM@91061|Bacilli,23JUW@182709|Oceanobacillus 91061|Bacilli S Oxidoreductase family, C-terminal alpha/beta domain - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C k141_31895_2 866895.HBHAL_5041 4.87e-84 256.0 COG0667@1|root,COG0667@2|Bacteria,1TPIY@1239|Firmicutes,4HA4Q@91061|Bacilli,3NEPW@45667|Halobacillus 91061|Bacilli C Aldo/keto reductase family - - - - - - - - - - - - Aldo_ket_red k141_36769_1 94122.Shewana3_2074 2.48e-40 146.0 COG1129@1|root,COG1129@2|Bacteria,1MU22@1224|Proteobacteria,1RMCH@1236|Gammaproteobacteria,2QA1P@267890|Shewanellaceae 1236|Gammaproteobacteria P Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system ytfR - 3.6.3.17 ko:K02056,ko:K10441 ko02010,map02010 M00212,M00221 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.2,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - iECED1_1282.ECED1_5085 ABC_tran k141_36769_2 94122.Shewana3_2075 6.94e-84 262.0 COG1172@1|root,COG1172@2|Bacteria,1MUM6@1224|Proteobacteria,1RRCX@1236|Gammaproteobacteria,2QEGJ@267890|Shewanellaceae 1236|Gammaproteobacteria G Branched-chain amino acid transport system / permease component ytfT GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - ko:K02057,ko:K10440 ko02010,map02010 M00212,M00221 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - iAPECO1_1312.APECO1_2162,iECH74115_1262.ECH74115_5749,iECOK1_1307.ECOK1_4745,iECSF_1327.ECSF_4119,iLF82_1304.LF82_3716,iUTI89_1310.UTI89_C4834,ic_1306.c5327 BPD_transp_2 k141_31896_2 1196324.A374_01524 2.12e-62 195.0 COG2963@1|root,COG2963@2|Bacteria,1V6PN@1239|Firmicutes,4HK4K@91061|Bacilli 91061|Bacilli L Transposase and inactivated derivatives - - - ko:K07483,ko:K09936 ko02024,map02024 - - - ko00000,ko00001,ko02000 2.A.7.21 - - HTH_28,Terminase_5 k141_30792_1 1453501.JELR01000001_gene3013 3.04e-73 229.0 COG2976@1|root,COG2976@2|Bacteria,1N117@1224|Proteobacteria,1S95P@1236|Gammaproteobacteria,467Y0@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria yfgM GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0009897,GO:0009986,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031233,GO:0044425,GO:0044459,GO:0044464,GO:0071575,GO:0071944,GO:0098552 - - - - - - - - - - TPR_21 k141_30792_2 1279017.AQYJ01000023_gene3144 9.47e-139 407.0 COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,1RN4V@1236|Gammaproteobacteria,4648Z@72275|Alteromonadaceae 1236|Gammaproteobacteria M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamB GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0008152,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0016491,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0042802,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0055114,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - ko:K17713 - - - - ko00000,ko02000 1.B.33.1 - - PQQ_2,PQQ_3 k141_8319_1 411901.BACCAC_03786 8.33e-16 75.5 2DMHR@1|root,32RMI@2|Bacteria,4NS7M@976|Bacteroidetes,2G2GT@200643|Bacteroidia 976|Bacteroidetes - - - - - - - - - - - - - - - k141_30793_1 1453501.JELR01000002_gene1392 1.7e-17 81.3 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,4648N@72275|Alteromonadaceae 1236|Gammaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family acrF - - ko:K18138 ko01501,ko01503,map01501,map01503 M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2 - - ACR_tran k141_15425_1 1453501.JELR01000005_gene1563 8.55e-223 647.0 COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,1SP6I@1236|Gammaproteobacteria,46516@72275|Alteromonadaceae 1236|Gammaproteobacteria P Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family helA - - ko:K15726 - - - - ko00000,ko02000 2.A.6.1.2 - - ACR_tran k141_15425_2 398579.Spea_0386 3.37e-15 75.9 COG0845@1|root,COG0845@2|Bacteria,1MX8W@1224|Proteobacteria,1RP9Q@1236|Gammaproteobacteria,2Q982@267890|Shewanellaceae 1236|Gammaproteobacteria M PFAM biotin lipoyl attachment domain-containing protein - - - ko:K15727 - - - - ko00000,ko02000 8.A.1.2.1 - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 k141_15426_1 1453501.JELR01000002_gene444 1.54e-78 249.0 COG2265@1|root,COG2265@2|Bacteria,1MV3A@1224|Proteobacteria,1RN1D@1236|Gammaproteobacteria,464C5@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA rlmD GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0070041,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.190 ko:K03215 - - - - ko00000,ko01000,ko03009 - - - TRAM,tRNA_U5-meth_tr k141_2598_2 91464.S7335_3034 3.78e-36 134.0 COG1125@1|root,COG1125@2|Bacteria,1G21Q@1117|Cyanobacteria,1H46T@1129|Synechococcus 1117|Cyanobacteria P Quaternary amine uptake ABC transporter (QAT) family, ATP-binding protein - - - ko:K05847 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - ABC_tran,CBS k141_4919_1 218284.CCDN010000001_gene14 2.02e-106 311.0 COG0681@1|root,COG0681@2|Bacteria,1V2BJ@1239|Firmicutes,4HGCB@91061|Bacilli,1ZRQR@1386|Bacillus 91061|Bacilli U Belongs to the peptidase S26 family sipS - 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24 k141_4919_2 441769.ABFU01000028_gene1394 8.29e-156 443.0 COG1161@1|root,COG1161@2|Bacteria,1TQGK@1239|Firmicutes,4HA4D@91061|Bacilli,1ZB63@1386|Bacillus 91061|Bacilli S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity rbgA GO:0003674,GO:0003824,GO:0003924,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022613,GO:0042254,GO:0044085,GO:0071840 - ko:K14540 - - - - ko00000,ko03009 - - - MMR_HSR1 k141_26398_1 218284.CCDN010000002_gene2325 1.1e-71 219.0 COG0702@1|root,COG0702@2|Bacteria,1TQFS@1239|Firmicutes,4HDA2@91061|Bacilli,1ZBH3@1386|Bacillus 91061|Bacilli GM NmrA-like family yhfK GO:0005575,GO:0005622,GO:0005623,GO:0044464 - - - - - - - - - - NAD_binding_10 k141_35810_1 1294265.JCM21738_2859 7.65e-28 108.0 COG0761@1|root,COG0761@2|Bacteria,1UHT7@1239|Firmicutes,4H9S4@91061|Bacilli,1ZAUG@1386|Bacillus 91061|Bacilli IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis ispH - 1.17.7.4 ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05884,R08210 RC01137,RC01487 ko00000,ko00001,ko00002,ko01000 - - - LYTB k141_23944_1 935836.JAEL01000098_gene1455 2.46e-101 311.0 COG0481@1|root,COG0481@2|Bacteria,1TP0G@1239|Firmicutes,4HASA@91061|Bacilli,1ZC7J@1386|Bacillus 91061|Bacilli M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner lepA - - ko:K03596 ko05134,map05134 - - - ko00000,ko00001 - - - EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C k141_276_1 1294265.JCM21738_4804 3.78e-106 325.0 COG1595@1|root,COG1595@2|Bacteria,1U9I0@1239|Firmicutes,4IJNF@91061|Bacilli,1ZC9D@1386|Bacillus 91061|Bacilli K Domain of unknown function (DUF4179) - - - - - - - - - - - - DUF4179,Sigma70_r4,Sigma70_r4_2,zf-HC2 k141_6221_1 218284.CCDN010000001_gene670 2.03e-31 110.0 2EQSH@1|root,33ICC@2|Bacteria,1VN5W@1239|Firmicutes,4HRDG@91061|Bacilli,1ZIX3@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_6221_2 218284.CCDN010000001_gene669 5e-20 89.4 COG0860@1|root,COG3103@1|root,COG3807@1|root,COG0860@2|Bacteria,COG3103@2|Bacteria,COG3807@2|Bacteria,1UYPW@1239|Firmicutes,4HBVT@91061|Bacilli,1ZDI1@1386|Bacillus 91061|Bacilli M COG3103 SH3 domain protein lytH GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - Amidase_3,SH3_3 k141_25142_1 1453501.JELR01000002_gene526 2.77e-05 43.9 2EAIM@1|root,334MN@2|Bacteria,1N6XM@1224|Proteobacteria,1SF6C@1236|Gammaproteobacteria,469A2@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_23945_1 196367.JNFG01000011_gene6139 4.1e-32 123.0 COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,2VHAX@28216|Betaproteobacteria,1K2GD@119060|Burkholderiaceae 28216|Betaproteobacteria P Sulfurtransferase sseA - 2.8.1.1,2.8.1.2 ko:K01011 ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122 - R01931,R03105,R03106 RC00214 ko00000,ko00001,ko01000 - - - Rhodanese k141_1341_1 10756.DIT9_BPPH2 1.69e-85 271.0 4QBPB@10239|Viruses,4QWHE@35237|dsDNA viruses no RNA stage,4QPPH@28883|Caudovirales,4QNRH@10744|Podoviridae 10744|Podoviridae - - - GO:0005575,GO:0019012,GO:0044423,GO:0098015 - - - - - - - - - - - k141_1341_2 10756.PORTL_BPPH2 7.48e-11 62.0 4QDW3@10239|Viruses 10239|Viruses S Phage Connector (GP10) - GO:0005575,GO:0008150,GO:0016032,GO:0019012,GO:0019028,GO:0019058,GO:0019068,GO:0019072,GO:0019073,GO:0032991,GO:0044403,GO:0044419,GO:0044423,GO:0046729,GO:0046798,GO:0051704 - - - - - - - - - - - k141_10849_1 1535422.ND16A_3282 2.51e-108 338.0 COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,1RYK4@1236|Gammaproteobacteria,2Q8FX@267889|Colwelliaceae 1236|Gammaproteobacteria V Beta-lactamase - - - - - - - - - - - - Beta-lactamase k141_16821_1 218284.CCDN010000005_gene3373 4.65e-56 186.0 COG0436@1|root,COG0436@2|Bacteria,1TQD6@1239|Firmicutes,4HAHQ@91061|Bacilli,1ZBB2@1386|Bacillus 91061|Bacilli E Aminotransferase mtnE - - ko:K08969 ko00270,ko01100,map00270,map01100 M00034 R07396 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k141_7341_1 218284.CCDN010000001_gene1264 7.2e-66 212.0 COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1TP4F@1239|Firmicutes,4HBNA@91061|Bacilli,1ZBTJ@1386|Bacillus 91061|Bacilli H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate ribD GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0016070,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 1.1.1.193,3.5.4.26 ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 M00125 R03458,R03459 RC00204,RC00933 ko00000,ko00001,ko00002,ko01000 - - - RibD_C,dCMP_cyt_deam_1 k141_31136_1 218284.CCDN010000001_gene609 1.15e-164 484.0 COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,4HB85@91061|Bacilli,1ZAS4@1386|Bacillus 91061|Bacilli J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner valS GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 k141_2600_1 218284.CCDN010000001_gene685 4.73e-207 592.0 COG0507@1|root,COG0507@2|Bacteria,1TPZH@1239|Firmicutes,4HATQ@91061|Bacilli,1ZAYS@1386|Bacillus 91061|Bacilli L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity recD2 - 3.1.11.5 ko:K03581 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_30,HHH_4,HHH_5,UvrD_C_2 k141_1342_1 218284.CCDN010000001_gene1736 8.16e-09 56.2 COG0075@1|root,COG3916@1|root,COG0075@2|Bacteria,COG3916@2|Bacteria,1TR3I@1239|Firmicutes,4HA6W@91061|Bacilli,1ZAT2@1386|Bacillus 91061|Bacilli E Aminotransferase class-V - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10,Acetyltransf_5,Acetyltransf_9,Aminotran_5 k141_1342_2 218284.CCDN010000001_gene1735 7.38e-77 247.0 COG1368@1|root,COG1368@2|Bacteria,1TRMA@1239|Firmicutes,4HFA5@91061|Bacilli,1ZDG2@1386|Bacillus 91061|Bacilli M Sulfatase - - - - - - - - - - - - Sulfatase k141_18088_2 218284.CCDN010000006_gene3517 3.89e-136 401.0 COG3263@1|root,COG3263@2|Bacteria,1TQPJ@1239|Firmicutes,4HC8I@91061|Bacilli,1ZC6H@1386|Bacillus 91061|Bacilli P COG3263 NhaP-type Na H and K H antiporters with a unique C-terminal domain cvrA - - ko:K11105 - - - - ko00000,ko02000 2.A.36.6 - - Na_H_Exchanger,TrkA_C k141_22770_1 218284.CCDN010000001_gene1814 1.29e-44 157.0 COG2508@1|root,COG2508@2|Bacteria,1TSQP@1239|Firmicutes,4HB10@91061|Bacilli,1ZBH4@1386|Bacillus 91061|Bacilli QT Purine catabolism regulatory protein-like family - - - ko:K09684 - - - - ko00000,ko03000 - - - HTH_30,PucR k141_23946_1 218284.CCDN010000005_gene3262 1.67e-157 445.0 COG0561@1|root,COG0561@2|Bacteria,1TREF@1239|Firmicutes,4H9Y9@91061|Bacilli,1ZC4W@1386|Bacillus 91061|Bacilli S hydrolases of the HAD superfamily yitU - 3.1.3.104 ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R07280 RC00017 ko00000,ko00001,ko00002,ko01000 - - - Hydrolase_3 k141_12095_1 218284.CCDN010000001_gene159 2.73e-36 123.0 COG5503@1|root,COG5503@2|Bacteria,1VEI7@1239|Firmicutes,4HNSK@91061|Bacilli,1ZIUI@1386|Bacillus 91061|Bacilli S Belongs to the UPF0356 family ykzG - - - - - - - - - - - DUF1447 k141_12095_2 441769.ABFU01000024_gene1009 1.09e-214 598.0 COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,4HAAP@91061|Bacilli,1ZBCD@1386|Bacillus 91061|Bacilli S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay rnjA GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004527,GO:0004532,GO:0004534,GO:0004540,GO:0005488,GO:0005515,GO:0006139,GO:0006364,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008409,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042802,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0090503,GO:0140098,GO:1901360 - ko:K12574 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - Lactamase_B,RMMBL k141_26402_1 935839.JAGJ01000001_gene1287 3.21e-47 159.0 COG1309@1|root,COG1309@2|Bacteria,2GM45@201174|Actinobacteria,4F4GC@85017|Promicromonosporaceae 201174|Actinobacteria K PFAM regulatory protein TetR - - - - - - - - - - - - TetR_C_6,TetR_N k141_4921_1 218284.CCDN010000005_gene3229 4.06e-157 478.0 COG1074@1|root,COG1074@2|Bacteria,1TQ35@1239|Firmicutes,4HA64@91061|Bacilli,1ZBG6@1386|Bacillus 91061|Bacilli L ATP-dependent helicase nuclease subunit A addA GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 3.6.4.12 ko:K16898 - - - - ko00000,ko01000,ko03400 - - - PDDEXK_1,UvrD-helicase,UvrD_C k141_1343_1 981383.AEWH01000068_gene396 8.49e-19 86.7 COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,4H9T3@91061|Bacilli 91061|Bacilli L DNA polymerase dnaE - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon k141_1343_2 218284.CCDN010000001_gene507 8.63e-64 196.0 2CBNY@1|root,330BE@2|Bacteria,1VGPH@1239|Firmicutes,4HNX7@91061|Bacilli,1ZH6P@1386|Bacillus 91061|Bacilli S Sporulation protein YtrH ytrH - - - - - - - - - - - Spore_YtrH k141_1343_3 218284.CCDN010000001_gene506 3.54e-86 256.0 2AV7G@1|root,31KY3@2|Bacteria,1V73K@1239|Firmicutes,4HJ3F@91061|Bacilli,1ZHIX@1386|Bacillus 91061|Bacilli - - ytrI - - - - - - - - - - - - k141_37001_1 1196031.ALEG01000008_gene5097 1.26e-09 54.7 2DS7W@1|root,33EX9@2|Bacteria,1VMQT@1239|Firmicutes,4HRVF@91061|Bacilli,1ZK2K@1386|Bacillus 91061|Bacilli S Fur-regulated basic protein B - - - - - - - - - - - - Fur_reg_FbpB k141_37001_2 218284.CCDN010000001_gene1505 5.3e-97 286.0 COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,4HJN1@91061|Bacilli,1ZFAP@1386|Bacillus 91061|Bacilli CO COG0526 Thiol-disulfide isomerase and thioredoxins stoA - - - - - - - - - - - AhpC-TSA k141_19175_1 223926.28805444 0.0 907.0 COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,1RN88@1236|Gammaproteobacteria,1XTZ7@135623|Vibrionales 135623|Vibrionales M Belongs to the MurCDEF family murC GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008763,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.8 ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M k141_19175_2 1116375.VEJY3_02080 1e-230 638.0 COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,1RMQ3@1236|Gammaproteobacteria,1XSDU@135623|Vibrionales 135623|Vibrionales M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) murG GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.4.1.227 ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 - R05032,R05662 RC00005,RC00049 ko00000,ko00001,ko01000,ko01011 - GT28 - Glyco_tran_28_C,Glyco_transf_28 k141_19175_3 223926.28805442 1.94e-268 737.0 COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,1RMIV@1236|Gammaproteobacteria,1XUU9@135623|Vibrionales 135623|Vibrionales D Peptidoglycan polymerase that is essential for cell division ftsW - - ko:K03588 ko04112,map04112 - - - ko00000,ko00001,ko02000,ko03036 2.A.103.1 - - FTSW_RODA_SPOVE k141_19175_4 1116375.VEJY3_02070 5.7e-283 777.0 COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,1RP25@1236|Gammaproteobacteria,1XUNN@135623|Vibrionales 135623|Vibrionales M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) murD GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008764,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase_C,Mur_ligase_M k141_19175_5 223926.28805440 4.42e-248 682.0 COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,1RNIG@1236|Gammaproteobacteria,1XSMD@135623|Vibrionales 135623|Vibrionales M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan mraY GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.8.13 ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 - R05629,R05630 RC00002,RC02753 ko00000,ko00001,ko01000,ko01011 9.B.146 - - Glycos_transf_4,MraY_sig1 k141_19175_6 1116375.VEJY3_02060 2.55e-290 797.0 COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,1RMGD@1236|Gammaproteobacteria,1XUMH@135623|Vibrionales 135623|Vibrionales M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein murF - 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 - R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M k141_19175_7 1116375.VEJY3_02055 1.01e-50 173.0 COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,1RMD6@1236|Gammaproteobacteria,1XUJ7@135623|Vibrionales 135623|Vibrionales M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan murE GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 ko:K01928 ko00300,ko00550,map00300,map00550 - R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M k141_20346_1 187944.H8YJ91_9CAUD 1.28e-17 85.1 4QAR1@10239|Viruses,4QUNA@35237|dsDNA viruses no RNA stage,4QPJE@28883|Caudovirales,4QM7A@10699|Siphoviridae 10699|Siphoviridae S ATPase family associated with various cellular activities (AAA) - - - - - - - - - - - - - k141_10850_1 552398.HMPREF0866_01115 1.38e-77 250.0 COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,2481I@186801|Clostridia,3WGMV@541000|Ruminococcaceae 186801|Clostridia K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth sigA - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 k141_6224_1 1236973.JCM9157_2336 1.4e-57 191.0 COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,4HAD5@91061|Bacilli,1ZC3C@1386|Bacillus 91061|Bacilli E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases gltD - 1.3.1.1 ko:K17722 ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100 M00046 R00977,R01414,R11026 RC00072,RC00123 ko00000,ko00001,ko00002,ko01000 - - - Fer4_20,Pyr_redox_2,Pyr_redox_3 k141_29874_1 1196031.ALEG01000028_gene4211 2.12e-155 452.0 COG1009@1|root,COG1009@2|Bacteria,1TQW4@1239|Firmicutes,4H9YR@91061|Bacilli,1ZAZ0@1386|Bacillus 91061|Bacilli CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit nuoL - 1.6.5.3 ko:K00341,ko:K05565 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000,ko02000 2.A.63.1,2.A.63.2,3.D.1 - - Proton_antipo_C,Proton_antipo_M,Proton_antipo_N k141_22771_1 1382305.AZUC01000009_gene1742 3.9e-35 127.0 COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,4H9V0@91061|Bacilli,26CVQ@186818|Planococcaceae 91061|Bacilli O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides ppiA GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 - - - ko00000,ko00001,ko01000,ko03110,ko04147 - - - Pro_isomerase k141_33451_1 218284.CCDN010000001_gene865 5.96e-71 222.0 2EPXN@1|root,33HI6@2|Bacteria,1VVBP@1239|Firmicutes,4HW76@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - k141_13293_2 1279017.AQYJ01000023_gene3134 1.41e-34 118.0 COG2975@1|root,COG2975@2|Bacteria,1N7C1@1224|Proteobacteria,1SC9F@1236|Gammaproteobacteria,4698C@72275|Alteromonadaceae 1236|Gammaproteobacteria S Iron-sulphur cluster assembly iscX GO:0003674,GO:0004857,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0030234,GO:0031163,GO:0043086,GO:0043167,GO:0043169,GO:0044085,GO:0044092,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050790,GO:0051186,GO:0065007,GO:0065009,GO:0071840,GO:0098772 - - - - - - - - - - Fe-S_assembly k141_13293_3 1279017.AQYJ01000023_gene3135 3.53e-89 262.0 COG0105@1|root,COG0105@2|Bacteria,1R9ZA@1224|Proteobacteria,1S1Z3@1236|Gammaproteobacteria,466Z4@72275|Alteromonadaceae 1236|Gammaproteobacteria F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate ndk GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 M00049,M00050,M00052,M00053 R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895 RC00002 ko00000,ko00001,ko00002,ko01000,ko04131 - - - NDK k141_13293_4 1279017.AQYJ01000023_gene3136 3.24e-250 689.0 COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,1RMUI@1236|Gammaproteobacteria,46420@72275|Alteromonadaceae 1236|Gammaproteobacteria J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs rlmN GO:0000049,GO:0000154,GO:0001510,GO:0002935,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016426,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0070040,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:0140102,GO:1901360,GO:1901363 2.1.1.192 ko:K06941 - - - - ko00000,ko01000,ko03009 - - - Radical_SAM k141_13293_5 1279017.AQYJ01000023_gene3139 1.6e-100 301.0 COG3063@1|root,COG3063@2|Bacteria,1RAFJ@1224|Proteobacteria,1S5H6@1236|Gammaproteobacteria,467DR@72275|Alteromonadaceae 1236|Gammaproteobacteria NU COG3063 Tfp pilus assembly protein PilF pilF - - ko:K02656 - - - - ko00000,ko02035,ko02044 - - - TPR_12,TPR_16,TPR_19,TPR_2,TPR_8 k141_13293_6 292415.Tbd_0593 1.19e-11 73.2 COG1426@1|root,COG4395@1|root,COG1426@2|Bacteria,COG4395@2|Bacteria,1N240@1224|Proteobacteria,2VVFV@28216|Betaproteobacteria,1KSP5@119069|Hydrogenophilales 119069|Hydrogenophilales S Helix-turn-helix domain - - - ko:K15539 - - - - ko00000 - - - DUF4115,HTH_25 k141_1344_1 1122915.AUGY01000008_gene5089 6.32e-31 120.0 COG0531@1|root,COG0531@2|Bacteria,1UF40@1239|Firmicutes,4ISDU@91061|Bacilli,2772G@186822|Paenibacillaceae 91061|Bacilli E Spore germination protein - - - ko:K06296 - - - - ko00000,ko02000 2.A.3.9.3 - - Spore_permease k141_7343_1 1453501.JELR01000002_gene670 1.83e-135 395.0 COG0457@1|root,COG0457@2|Bacteria,1MVCA@1224|Proteobacteria,1RS02@1236|Gammaproteobacteria,464BM@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0457 FOG TPR repeat - - - - - - - - - - - - ANAPC3,TPR_16,TPR_8 k141_18101_1 1232683.ADIMK_2589 5.35e-86 273.0 COG3119@1|root,COG3119@2|Bacteria,1MV92@1224|Proteobacteria,1RPDE@1236|Gammaproteobacteria,464V5@72275|Alteromonadaceae 1236|Gammaproteobacteria P Sulfatase atsA - 3.1.6.1 ko:K01130 ko00140,ko00600,map00140,map00600 - R03980,R04856 RC00128,RC00231 ko00000,ko00001,ko01000 - - - Sulfatase k141_33472_1 218284.CCDN010000010_gene4386 2.29e-210 588.0 COG0215@1|root,COG0215@2|Bacteria,1TP9D@1239|Firmicutes,4HA6D@91061|Bacilli,1ZB69@1386|Bacillus 91061|Bacilli J Belongs to the class-I aminoacyl-tRNA synthetase family cysS GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 6.1.1.16 ko:K01883 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_2,tRNA-synt_1e,tRNA-synt_1g k141_3815_1 379066.GAU_2058 8.3e-25 105.0 COG2010@1|root,COG2010@2|Bacteria,1ZUJA@142182|Gemmatimonadetes 142182|Gemmatimonadetes C Cytochrome C oxidase, cbb3-type, subunit III - - - - - - - - - - - - - k141_20353_1 1279017.AQYJ01000019_gene1484 1.01e-69 220.0 COG1091@1|root,COG1091@2|Bacteria,1MUXM@1224|Proteobacteria,1S1MF@1236|Gammaproteobacteria,468FS@72275|Alteromonadaceae 1236|Gammaproteobacteria M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose - - 1.1.1.133 ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777 RC00182 ko00000,ko00001,ko00002,ko01000 - - - RmlD_sub_bind k141_20353_2 1279017.AQYJ01000019_gene1485 1.04e-248 688.0 COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria,46552@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ Belongs to the beta-ketoacyl-ACP synthases family fabB - 2.3.1.41 ko:K00647 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt k141_20353_3 1279017.AQYJ01000019_gene1486 5.95e-126 358.0 COG0764@1|root,COG0764@2|Bacteria,1MWV8@1224|Proteobacteria,1RP6W@1236|Gammaproteobacteria,4657R@72275|Alteromonadaceae 1236|Gammaproteobacteria I Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length fabA - 4.2.1.59,5.3.3.14 ko:K01716 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00083 R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07639 RC00831,RC01078,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FabA k141_35828_1 42565.FP66_11430 2.32e-141 415.0 COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria,1XICM@135619|Oceanospirillales 135619|Oceanospirillales V (ABC) transporter - - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran k141_6256_1 42565.FP66_02890 1.48e-108 314.0 COG0118@1|root,COG0118@2|Bacteria,1MU4X@1224|Proteobacteria,1RRP3@1236|Gammaproteobacteria,1XHZW@135619|Oceanospirillales 135619|Oceanospirillales E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR hisH - - ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - - GATase k141_6256_2 42565.FP66_02895 1.42e-10 59.3 COG0131@1|root,COG0131@2|Bacteria,1MWBS@1224|Proteobacteria,1RPA9@1236|Gammaproteobacteria,1XIRE@135619|Oceanospirillales 135619|Oceanospirillales E Imidazoleglycerol-phosphate dehydratase hisB - 4.2.1.19 ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R03457 RC00932 ko00000,ko00001,ko00002,ko01000 - - - IGPD k141_28789_1 218284.CCDN010000001_gene253 2.11e-191 558.0 COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,4HAWB@91061|Bacilli,1ZAQK@1386|Bacillus 91061|Bacilli J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS - 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1 k141_22780_1 218284.CCDN010000001_gene1251 7.68e-72 218.0 COG1670@1|root,COG1670@2|Bacteria,1V0BB@1239|Firmicutes,4HAK2@91061|Bacilli,1ZDJN@1386|Bacillus 91061|Bacilli J Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_3 k141_26420_1 223926.28807889 1.53e-116 345.0 COG1027@1|root,COG1027@2|Bacteria,1R9JY@1224|Proteobacteria,1RP5Z@1236|Gammaproteobacteria,1XSMK@135623|Vibrionales 135623|Vibrionales E Aspartate ammonia-lyase aspA - 4.3.1.1 ko:K01744 ko00250,ko01100,map00250,map01100 - R00490 RC00316,RC02799 ko00000,ko00001,ko01000 - - - FumaraseC_C,Lyase_1 k141_7354_1 1185653.A1A1_00800 5.26e-97 298.0 COG1232@1|root,COG1232@2|Bacteria,1TQ6W@1239|Firmicutes,4HAUG@91061|Bacilli,26DWQ@186818|Planococcaceae 91061|Bacilli H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX hemG - 1.3.3.15,1.3.3.4 ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03222,R04178 RC00885 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS09325 Amino_oxidase k141_18102_1 218284.CCDN010000002_gene2229 2.86e-92 293.0 COG5000@1|root,COG5002@1|root,COG5000@2|Bacteria,COG5002@2|Bacteria,1VS6X@1239|Firmicutes,4HV7W@91061|Bacilli,1ZS6R@1386|Bacillus 91061|Bacilli T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,dCache_1 k141_3816_1 358681.BBR47_48070 9.92e-31 123.0 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4HB97@91061|Bacilli,26T63@186822|Paenibacillaceae 91061|Bacilli C Belongs to the aldehyde dehydrogenase family - - 1.2.99.10 ko:K22445 - - - - ko00000,ko01000 - - - Aldedh k141_33473_1 1453501.JELR01000002_gene1066 1.65e-96 285.0 COG1999@1|root,COG1999@2|Bacteria,1RHJ8@1224|Proteobacteria,1SYEA@1236|Gammaproteobacteria,46CW7@72275|Alteromonadaceae 1236|Gammaproteobacteria S SCO1/SenC - - - ko:K07152 - - - - ko00000,ko03029 - - - SCO1-SenC k141_2618_1 218284.CCDN010000007_gene4031 2.87e-120 360.0 COG4715@1|root,COG4715@2|Bacteria,1TSUG@1239|Firmicutes,4HGS4@91061|Bacilli,1ZC8Y@1386|Bacillus 91061|Bacilli S Zinc finger, swim domain protein - - - - - - - - - - - - SWIM k141_34662_1 1294265.JCM21738_3545 2.95e-216 607.0 COG0843@1|root,COG0843@2|Bacteria,1TRC2@1239|Firmicutes,4HDTI@91061|Bacilli,1ZR6V@1386|Bacillus 91061|Bacilli C COG0843 Heme copper-type cytochrome quinol oxidases, subunit 1 - - 1.9.3.1 ko:K02274 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6 - - COX1 k141_31170_1 218284.CCDN010000001_gene1864 2.57e-90 277.0 COG0612@1|root,COG0612@2|Bacteria,1TPN6@1239|Firmicutes,4H9P5@91061|Bacilli,1ZCAJ@1386|Bacillus 91061|Bacilli S Peptidase M16 albE - - - - - - - - - - - Peptidase_M16_C k141_31170_2 218284.CCDN010000001_gene1865 1.47e-70 220.0 COG1079@1|root,COG1079@2|Bacteria,1TP8Y@1239|Firmicutes,4HAX4@91061|Bacilli,1ZAYF@1386|Bacillus 91061|Bacilli S Belongs to the binding-protein-dependent transport system permease family yufQ - - ko:K02057 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - BPD_transp_2 k141_14496_1 1453501.JELR01000005_gene1758 1.15e-12 65.9 COG1210@1|root,COG1210@2|Bacteria,1MV5F@1224|Proteobacteria,1RNDX@1236|Gammaproteobacteria,4650D@72275|Alteromonadaceae 1236|Gammaproteobacteria M UTP-glucose-1-phosphate uridylyltransferase galU - 2.7.7.9 ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 M00129,M00361,M00362,M00549 R00289 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase k141_25174_1 1408303.JNJJ01000002_gene3954 3.15e-62 216.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,4H9S7@91061|Bacilli,1ZB6Y@1386|Bacillus 91061|Bacilli L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A k141_28790_2 218284.CCDN010000001_gene1405 8.17e-52 167.0 COG0425@1|root,COG0607@1|root,COG0425@2|Bacteria,COG0607@2|Bacteria,1V1GU@1239|Firmicutes,4HFR8@91061|Bacilli,1ZAVN@1386|Bacillus 91061|Bacilli OP Belongs to the sulfur carrier protein TusA family yrkF - - - - - - - - - - - Rhodanese,TusA k141_7355_1 1453501.JELR01000002_gene167 1.13e-37 132.0 COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,1RMR8@1236|Gammaproteobacteria,4652T@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1230 Co Zn Cd efflux system component - - - ko:K16264 - - - - ko00000,ko02000 2.A.4.1 - - Cation_efflux k141_7355_2 1279017.AQYJ01000024_gene1017 8.5e-21 93.2 COG3608@1|root,COG3608@2|Bacteria,1MUAA@1224|Proteobacteria,1RNQQ@1236|Gammaproteobacteria,464NX@72275|Alteromonadaceae 1236|Gammaproteobacteria S Succinylglutamate desuccinylase / Aspartoacylase family - - - ko:K06987 - - - - ko00000 - - - AstE_AspA k141_3817_1 767817.Desgi_0419 1.32e-57 201.0 COG1529@1|root,COG1529@2|Bacteria,1TP7U@1239|Firmicutes,248BV@186801|Clostridia 186801|Clostridia C aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - - - - - - - - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 k141_9680_1 1347087.CBYO010000022_gene3812 7.73e-14 70.1 COG4818@1|root,COG4818@2|Bacteria,1VBIZ@1239|Firmicutes,4HKBZ@91061|Bacilli 91061|Bacilli S membrane - - - - - - - - - - - - DUF4870 k141_13307_1 1294265.JCM21738_3956 1.37e-44 145.0 COG0268@1|root,COG0268@2|Bacteria,1VEGX@1239|Firmicutes,4HNJS@91061|Bacilli,1ZI3X@1386|Bacillus 91061|Bacilli J Binds directly to 16S ribosomal RNA rpsT - - ko:K02968 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S20p k141_34663_1 441769.ABFU01000024_gene1003 3.58e-66 213.0 COG1271@1|root,COG1271@2|Bacteria,1TRH4@1239|Firmicutes,4HA19@91061|Bacilli,1ZBAG@1386|Bacillus 91061|Bacilli C oxidase, subunit cydA - 1.10.3.14 ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - Cyt_bd_oxida_I k141_296_1 1294265.JCM21738_4633 1.64e-102 297.0 COG1488@1|root,COG1488@2|Bacteria,1TPDW@1239|Firmicutes,4HAI4@91061|Bacilli,1ZCGY@1386|Bacillus 91061|Bacilli H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP pncB - 6.3.4.21 ko:K00763 ko00760,ko01100,map00760,map01100 - R01724 RC00033 ko00000,ko00001,ko01000 - - - QRPTase_C,QRPTase_N k141_4934_1 223926.28806517 6.78e-249 684.0 COG0687@1|root,COG0687@2|Bacteria,1MUYW@1224|Proteobacteria,1RM7W@1236|Gammaproteobacteria,1XUPM@135623|Vibrionales 135623|Vibrionales P Required for the activity of the bacterial periplasmic transport system of putrescine - - - ko:K11069 ko02010,map02010 M00299 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 - - SBP_bac_8 k141_18103_1 1279017.AQYJ01000026_gene58 8.69e-123 395.0 COG1361@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4932@2|Bacteria,1R5G4@1224|Proteobacteria,1SEWA@1236|Gammaproteobacteria,469S7@72275|Alteromonadaceae 1236|Gammaproteobacteria M Domain of unknown function DUF11 - - - - - - - - - - - - DUF11,SdrD_B k141_20354_1 218284.CCDN010000001_gene1959 5.9e-128 380.0 COG2766@1|root,COG2766@2|Bacteria,1TRTW@1239|Firmicutes,4HA8A@91061|Bacilli,1ZBM9@1386|Bacillus 91061|Bacilli T Ser protein kinase prkA - - ko:K07180 - - - - ko00000 - - - AAA_PrkA,PrkA k141_12130_1 218284.CCDN010000005_gene3383 1.78e-175 490.0 COG0396@1|root,COG0396@2|Bacteria,1TQ98@1239|Firmicutes,4HAD9@91061|Bacilli,1ZAW4@1386|Bacillus 91061|Bacilli O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component sufC - - ko:K09013 - - - - ko00000,ko02000 - - - ABC_tran k141_3818_1 218284.CCDN010000005_gene3280 2.17e-95 293.0 COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,4HAMK@91061|Bacilli,1ZBB4@1386|Bacillus 91061|Bacilli E ABC transporter substrate-binding protein oppA - - ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 k141_26699_1 223926.28809340 0.0 1126.0 COG3523@1|root,COG3523@2|Bacteria,1MV3D@1224|Proteobacteria,1RPQ2@1236|Gammaproteobacteria,1XSAX@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria - - - ko:K11891 ko02025,ko03070,map02025,map03070 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - IcmF-related,IcmF_C,ImcF-related_N k141_20508_1 866895.HBHAL_4750 2.35e-82 255.0 COG0477@1|root,COG2814@2|Bacteria,1TQHD@1239|Firmicutes,4HBCZ@91061|Bacilli,3NEBC@45667|Halobacillus 91061|Bacilli EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1,Sugar_tr k141_33653_1 649639.Bcell_0920 6.84e-17 82.8 28PM4@1|root,2ZCA8@2|Bacteria,1V1PA@1239|Firmicutes,4HFNN@91061|Bacilli,1ZG8T@1386|Bacillus 91061|Bacilli S YtkA-like - - - - - - - - - - - - YtkA k141_33653_2 1196031.ALEG01000008_gene4996 9.03e-38 133.0 COG4359@1|root,COG4359@2|Bacteria,1V1V0@1239|Firmicutes,4HC1U@91061|Bacilli,1ZEJT@1386|Bacillus 91061|Bacilli E conserved protein, possibly involved in methylthioadenosine recycling - - - - - - - - - - - - HAD,Put_Phosphatase k141_15818_2 218284.CCDN010000002_gene2219 3.14e-81 251.0 COG1017@1|root,COG1018@1|root,COG1017@2|Bacteria,COG1018@2|Bacteria,1TRG2@1239|Firmicutes,4HAU3@91061|Bacilli,1ZAP9@1386|Bacillus 91061|Bacilli C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress hmp GO:0000166,GO:0001505,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008941,GO:0009056,GO:0009987,GO:0016491,GO:0016705,GO:0016708,GO:0017144,GO:0033554,GO:0034641,GO:0036094,GO:0042133,GO:0042135,GO:0042737,GO:0043167,GO:0043168,GO:0044237,GO:0044248,GO:0044270,GO:0044464,GO:0046209,GO:0046210,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051213,GO:0051409,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0071500,GO:0071949,GO:0072593,GO:0097159,GO:1901265,GO:1901363,GO:2001057 1.14.12.17,1.18.1.3 ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 M00538 R02550,R03562,R05666,R09513 RC00269,RC00490,RC02556 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_6,Globin,NAD_binding_1 k141_25333_1 1116375.VEJY3_05370 1.13e-155 466.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1XSPS@135623|Vibrionales 135623|Vibrionales U COG0841 Cation multidrug efflux pump acrB - - ko:K18138 ko01501,ko01503,map01501,map01503 M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2 - - ACR_tran k141_6422_1 240302.BN982_02498 1.98e-163 463.0 COG0524@1|root,COG0524@2|Bacteria,1TQRC@1239|Firmicutes,4HA87@91061|Bacilli,3NE5C@45667|Halobacillus 91061|Bacilli G Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway rbsK GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046835,GO:0071704 2.7.1.15 ko:K00852 ko00030,map00030 - R01051,R02750 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB k141_6422_2 240302.BN982_02499 1.7e-67 213.0 COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,4H9V1@91061|Bacilli,3NEJY@45667|Halobacillus 91061|Bacilli K helix_turn _helix lactose operon repressor rbsR - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 k141_13517_1 218284.CCDN010000001_gene985 1.01e-170 480.0 COG1071@1|root,COG1071@2|Bacteria,1TQDG@1239|Firmicutes,4HBEQ@91061|Bacilli,1ZCCJ@1386|Bacillus 91061|Bacilli C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit bfmBAA - 1.2.4.4 ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 M00036 R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00027,RC00627,RC02743,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS07640 E1_dh k141_26700_1 218284.CCDN010000005_gene3344 7.51e-71 222.0 COG1363@1|root,COG1363@2|Bacteria,1TQ86@1239|Firmicutes,4HBDK@91061|Bacilli,1ZBP8@1386|Bacillus 91061|Bacilli G peptidase M42 yhfE - - - - - - - - - - - Peptidase_M42 k141_11072_1 1168065.DOK_03753 1.07e-17 81.3 COG3086@1|root,COG3086@2|Bacteria,1QJ6E@1224|Proteobacteria,1TH3Z@1236|Gammaproteobacteria,1J6HP@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria T COG3086 Positive regulator of sigma E activity - - - ko:K03803 - - - - ko00000,ko03021 - - - RseC_MucC k141_11072_2 1279017.AQYJ01000026_gene287 8.44e-134 391.0 COG3026@1|root,COG3026@2|Bacteria,1MUQ8@1224|Proteobacteria,1RNF3@1236|Gammaproteobacteria,467RQ@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG3026 Negative regulator of sigma E activity rseB GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0044464,GO:0045152 - ko:K03598 - - - - ko00000,ko03021 - - - MucB_RseB,MucB_RseB_C k141_16999_1 218284.CCDN010000008_gene4099 1.46e-167 475.0 COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,4HB0P@91061|Bacilli,1ZQFT@1386|Bacillus 91061|Bacilli L transposase mutator type - - - - - - - - - - - - Transposase_mut k141_18240_1 235909.GK0177 1.01e-61 200.0 COG0601@1|root,COG0601@2|Bacteria,1VCQ9@1239|Firmicutes,4HMZ6@91061|Bacilli,1WH2I@129337|Geobacillus 91061|Bacilli P Binding-protein-dependent transport system inner membrane component - - - ko:K02033 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 k141_37130_1 1279017.AQYJ01000025_gene748 6.35e-279 784.0 COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,1RMS8@1236|Gammaproteobacteria,4657M@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) slt GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009274,GO:0016740,GO:0016757,GO:0030203,GO:0030288,GO:0030312,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - ko:K08309 - - - - ko00000,ko01000,ko01011 - GH23 iETEC_1333.ETEC_4747,iPC815.YPO0452 SLT,SLT_L k141_37130_2 1279017.AQYJ01000025_gene747 0.0 920.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPCU@1236|Gammaproteobacteria,463XW@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0488 ATPase components of ABC transporters with duplicated ATPase domains uup GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010528,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0031323,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0070894,GO:0071944,GO:0080090,GO:0097159,GO:1901363 - ko:K15738 - - - - ko00000,ko02000 3.A.1.120.6 - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn k141_37130_3 1042377.AFPJ01000007_gene1919 1.85e-70 215.0 COG0589@1|root,COG0589@2|Bacteria,1RHE6@1224|Proteobacteria,1S6AR@1236|Gammaproteobacteria,467I4@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0589 Universal stress protein UspA and related nucleotide-binding proteins uspA - - ko:K06149 - - - - ko00000 - - - Usp k141_37130_4 1453501.JELR01000001_gene2487 1.1e-68 213.0 2C1GI@1|root,33B43@2|Bacteria,1NJE7@1224|Proteobacteria,1SH3D@1236|Gammaproteobacteria,468W3@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_37130_5 1279017.AQYJ01000025_gene744 0.0 1576.0 COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,1RNZ2@1236|Gammaproteobacteria,463YR@72275|Alteromonadaceae 1236|Gammaproteobacteria L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topA GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.2 ko:K03168 - - - - ko00000,ko01000,ko03032,ko03400 - - - Topo_Zn_Ribbon,Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom k141_37130_7 1453501.JELR01000001_gene2484 1.55e-33 117.0 2EHUF@1|root,33BK2@2|Bacteria,1NMAC@1224|Proteobacteria,1SGY0@1236|Gammaproteobacteria,46950@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_37130_8 1453501.JELR01000001_gene2483 7.43e-129 367.0 COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,1RMXF@1236|Gammaproteobacteria,4648J@72275|Alteromonadaceae 1236|Gammaproteobacteria K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair lexA GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006282,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032774,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0048583,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0071704,GO:0080090,GO:0080134,GO:0080135,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001020,GO:2001141 3.4.21.88 ko:K01356 - M00729 - - ko00000,ko00002,ko01000,ko01002,ko03400 - - - LexA_DNA_bind,Peptidase_S24 k141_37130_9 1279017.AQYJ01000025_gene740 2.61e-125 359.0 COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,1S032@1236|Gammaproteobacteria,469CA@72275|Alteromonadaceae 1236|Gammaproteobacteria S Rossmann fold nucleotide-binding protein - - 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - Lysine_decarbox k141_37130_10 1121937.AUHJ01000005_gene2302 4.34e-14 69.7 2E600@1|root,330PC@2|Bacteria,1N9V9@1224|Proteobacteria,1SD3Y@1236|Gammaproteobacteria,468XD@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_37130_11 1279017.AQYJ01000025_gene738 4.25e-116 336.0 COG1309@1|root,COG1309@2|Bacteria,1RDIM@1224|Proteobacteria,1S4DI@1236|Gammaproteobacteria,467NJ@72275|Alteromonadaceae 1236|Gammaproteobacteria K Transcriptional regulator psrA - - - - - - - - - - - TetR_N k141_12379_3 1116375.VEJY3_16551 1.09e-185 517.0 COG0637@1|root,COG0637@2|Bacteria,1MX6B@1224|Proteobacteria,1RQPM@1236|Gammaproteobacteria,1XTCI@135623|Vibrionales 135623|Vibrionales S Belongs to the HAD-like hydrolase superfamily. PhnX family phnX GO:0003674,GO:0003824 3.11.1.1 ko:K05306 ko00440,ko01100,ko01120,map00440,map01100,map01120 - R00747 RC00368 ko00000,ko00001,ko01000 - - - HAD_2 k141_12379_4 1116375.VEJY3_16556 2.07e-272 749.0 COG0160@1|root,COG0160@2|Bacteria,1QTZ3@1224|Proteobacteria,1RXZS@1236|Gammaproteobacteria,1XU9C@135623|Vibrionales 135623|Vibrionales H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - 2.6.1.19 ko:K00823 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 M00027 R00908,R01648 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 k141_9922_1 1123237.Salmuc_01278 1.73e-84 256.0 COG0583@1|root,COG0583@2|Bacteria,1MUIX@1224|Proteobacteria,2TT9N@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Transcriptional regulator metR - - ko:K03576 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate k141_32369_2 1279017.AQYJ01000027_gene1870 2.86e-85 258.0 COG0500@1|root,COG0500@2|Bacteria,1RDHE@1224|Proteobacteria,1S3U0@1236|Gammaproteobacteria,46D40@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Protein of unknown function (DUF938) - - - - - - - - - - - - DUF938 k141_17020_1 1444310.JANV01000170_gene2415 2.73e-26 102.0 COG1846@1|root,COG1846@2|Bacteria,1VDGD@1239|Firmicutes,4HYE5@91061|Bacilli,1ZQ40@1386|Bacillus 91061|Bacilli K helix_turn_helix multiple antibiotic resistance protein - - - - - - - - - - - - MarR k141_37159_1 218284.CCDN010000001_gene1946 3.94e-84 253.0 COG2968@1|root,COG2968@2|Bacteria,1VB7C@1239|Firmicutes,4HH35@91061|Bacilli,1ZGZ6@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF541) bp26 - - ko:K09807 - - - - ko00000 - - - SIMPL k141_5124_1 1279017.AQYJ01000028_gene2142 7.23e-96 279.0 COG3565@1|root,COG3565@2|Bacteria,1RD7C@1224|Proteobacteria,1S6SD@1236|Gammaproteobacteria,467BD@72275|Alteromonadaceae 1236|Gammaproteobacteria S dioxygenase of extradiol dioxygenase family - - - ko:K06991 - - - - ko00000 - - - Glyoxalase k141_34830_1 997296.PB1_13674 3.76e-58 185.0 COG0503@1|root,COG0503@2|Bacteria,1V1DU@1239|Firmicutes,4HFNW@91061|Bacilli,1ZFTS@1386|Bacillus 91061|Bacilli F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis xpt - 2.4.2.22 ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 - R01229,R02142 RC00063,RC00122 ko00000,ko00001,ko01000 - - iYO844.BSU22070 Pribosyltran k141_25359_1 1042377.AFPJ01000032_gene2700 1.17e-207 578.0 COG0524@1|root,COG0524@2|Bacteria,1MUUC@1224|Proteobacteria,1RMN2@1236|Gammaproteobacteria,464Y8@72275|Alteromonadaceae 1236|Gammaproteobacteria G pfkB family carbohydrate kinase gsk GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008906,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237 2.7.1.15,2.7.1.4,2.7.1.73 ko:K00847,ko:K00852,ko:K00892 ko00030,ko00051,ko00230,ko00500,ko00520,ko01100,map00030,map00051,map00230,map00500,map00520,map01100 - R00760,R00867,R01051,R01131,R01228,R02750,R03920 RC00002,RC00017 ko00000,ko00001,ko01000 - - iSDY_1059.SDY_0442 PfkB k141_30001_2 218284.CCDN010000012_gene4435 2.28e-123 364.0 COG1686@1|root,COG1686@2|Bacteria,1TQN0@1239|Firmicutes,4HBD4@91061|Bacilli,1ZAS6@1386|Bacillus 91061|Bacilli M Belongs to the peptidase S11 family dacA GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0009002,GO:0016787,GO:0017171,GO:0019538,GO:0030312,GO:0043170,GO:0044238,GO:0044464,GO:0070008,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.16.4 ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - PBP5_C,Peptidase_S11 k141_14611_1 983545.Glaag_2763 6.23e-53 172.0 COG3832@1|root,COG3832@2|Bacteria,1N2PR@1224|Proteobacteria,1S71Z@1236|Gammaproteobacteria,46AN6@72275|Alteromonadaceae 1236|Gammaproteobacteria J glyoxalase III activity - - - - - - - - - - - - AHSA1,Polyketide_cyc2 k141_24123_2 1453501.JELR01000002_gene776 3.88e-80 246.0 COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,1RNXV@1236|Gammaproteobacteria,4661X@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) trpD GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 ko:K00766 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R01073 RC00440 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_0421 Glycos_trans_3N,Glycos_transf_3 k141_1522_1 218284.CCDN010000004_gene3117 3.97e-121 352.0 COG1533@1|root,COG1533@2|Bacteria,1TPA3@1239|Firmicutes,4HACB@91061|Bacilli,1ZBPU@1386|Bacillus 91061|Bacilli L Spore photoproduct lyase splB GO:0003674,GO:0003824,GO:0003913,GO:0005488,GO:0005575,GO:0005623,GO:0016829,GO:0016830,GO:0042601,GO:0042763,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0070283,GO:0140097 4.1.99.14 ko:K03716 - - - - ko00000,ko01000 - - - - k141_488_1 1453501.JELR01000001_gene3236 9.69e-238 662.0 2C612@1|root,32RGH@2|Bacteria,1RGYZ@1224|Proteobacteria,1S8MM@1236|Gammaproteobacteria,46BBZ@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_488_5 1453501.JELR01000001_gene3241 2.82e-85 270.0 COG0457@1|root,COG0457@2|Bacteria,1RC07@1224|Proteobacteria,1S36N@1236|Gammaproteobacteria,46864@72275|Alteromonadaceae 1236|Gammaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_8 k141_9923_2 99598.Cal7507_3732 1.02e-44 148.0 COG1652@1|root,COG1652@2|Bacteria 2|Bacteria S positive regulation of growth rate ygaU GO:0003674,GO:0005488,GO:0008150,GO:0010035,GO:0010038,GO:0030955,GO:0031420,GO:0035864,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896 - - - - - - - - - - BON,LysM k141_9923_3 1123392.AQWL01000008_gene1230 3.32e-33 120.0 2CI52@1|root,2ZC5H@2|Bacteria,1R9WI@1224|Proteobacteria,2VQZX@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k141_19396_1 1385510.N781_09575 2.28e-90 276.0 COG3104@1|root,COG3104@2|Bacteria,1UHSN@1239|Firmicutes,4IS8A@91061|Bacilli 91061|Bacilli E Major Facilitator Superfamily lmrP - - ko:K08152 - - - - ko00000,ko02000 2.A.1.2 - - MFS_1,Sugar_tr k141_11088_2 1219080.VEZ01S_08_00690 8.84e-186 518.0 COG2378@1|root,COG2378@2|Bacteria,1Q19K@1224|Proteobacteria,1RZ1N@1236|Gammaproteobacteria,1XUZ2@135623|Vibrionales 135623|Vibrionales K WYL domain - - - - - - - - - - - - WYL k141_11088_5 398579.Spea_1267 7.1e-241 669.0 28MZW@1|root,2ZB6I@2|Bacteria,1RCF3@1224|Proteobacteria,1SAMK@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_11088_6 398579.Spea_1268 0.0 948.0 28JZ8@1|root,2Z9PB@2|Bacteria,1R6WD@1224|Proteobacteria,1SBEU@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_11088_7 398579.Spea_1269 0.0 951.0 COG0553@1|root,COG0553@2|Bacteria,1MX26@1224|Proteobacteria,1RZZU@1236|Gammaproteobacteria 1236|Gammaproteobacteria L DEAD-like helicases superfamily - - - - - - - - - - - - Helicase_C k141_23039_2 1453501.JELR01000002_gene1074 0.0 1016.0 COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,1RPC3@1236|Gammaproteobacteria,46490@72275|Alteromonadaceae 1236|Gammaproteobacteria C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B ctaD - 1.9.3.1 ko:K02274 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6 - iJN746.PP_0104 COX1 k141_1523_1 218284.CCDN010000001_gene655 1.53e-74 224.0 2E8Q1@1|root,33314@2|Bacteria,1VFPE@1239|Firmicutes,4HPJ2@91061|Bacilli,1ZHSS@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3792) yrzE - - - - - - - - - - - DUF3792 k141_12382_1 1294265.JCM21738_4273 1.59e-40 140.0 COG1309@1|root,COG1309@2|Bacteria,1TP0U@1239|Firmicutes,4HE9Q@91061|Bacilli,1ZBMJ@1386|Bacillus 91061|Bacilli K COG1309 Transcriptional regulator - - - - - - - - - - - - TetR_N k141_12382_2 1294265.JCM21738_4274 5.2e-22 94.0 COG0477@1|root,COG2814@2|Bacteria,1TPRN@1239|Firmicutes,4H9VV@91061|Bacilli,1ZAXQ@1386|Bacillus 91061|Bacilli EGP the major facilitator superfamily - - - - - - - - - - - - MFS_1 k141_20529_1 240302.BN982_02467 1.14e-103 311.0 COG3037@1|root,COG3037@2|Bacteria,1TQK5@1239|Firmicutes,4HBAD@91061|Bacilli,3NDD4@45667|Halobacillus 91061|Bacilli S PTS system sugar-specific permease component ulaA - - ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 M00283,M00550 R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.7.1 - - EIIC-GAT k141_32370_1 1042377.AFPJ01000042_gene1015 9.32e-65 218.0 COG1472@1|root,COG1472@2|Bacteria,1MVAJ@1224|Proteobacteria,1RMQF@1236|Gammaproteobacteria,465G4@72275|Alteromonadaceae 1236|Gammaproteobacteria G Beta-N-acetylhexosaminidase ybbD - 3.2.1.52 ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 M00628 R00022,R05963,R07809,R07810,R10831 RC00049 ko00000,ko00001,ko00002,ko01000 - - - Glyco_hydro_3,Glyco_hydro_3_C k141_25361_1 218284.CCDN010000005_gene3192 2.82e-102 303.0 COG0407@1|root,COG0407@2|Bacteria,1TR8Q@1239|Firmicutes,4HAXT@91061|Bacilli,1ZDGX@1386|Bacillus 91061|Bacilli H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III hemE GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03197,R04972 RC00872 ko00000,ko00001,ko00002,ko01000 - - - URO-D k141_17021_1 342610.Patl_2922 1.21e-42 152.0 COG1506@1|root,COG1506@2|Bacteria,1QWCQ@1224|Proteobacteria,1S38C@1236|Gammaproteobacteria,2Q3TM@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria E alpha/beta hydrolase fold - - - - - - - - - - - - Abhydrolase_3,Abhydrolase_6 k141_30002_2 1279017.AQYJ01000025_gene569 5.81e-33 114.0 2EH9I@1|root,33B1E@2|Bacteria,1NH43@1224|Proteobacteria,1SD9Y@1236|Gammaproteobacteria,4692W@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF2788) - - - - - - - - - - - - DUF2788 k141_18265_1 1294265.JCM21738_1319 4.4e-50 159.0 2EACT@1|root,334GP@2|Bacteria,1VJJM@1239|Firmicutes,4HQ2Z@91061|Bacilli,1ZJ49@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF1871) yugE - - - - - - - - - - - DUF1871 k141_18265_2 1294265.JCM21738_1320 1.27e-12 63.9 COG1168@1|root,COG1168@2|Bacteria,1TP5G@1239|Firmicutes,4H9PE@91061|Bacilli,1ZCQC@1386|Bacillus 91061|Bacilli E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities patB - 4.4.1.8 ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 - R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 k141_11089_1 218284.CCDN010000001_gene1759 7.86e-122 358.0 COG1502@1|root,COG1502@2|Bacteria,1USPT@1239|Firmicutes,4HCJD@91061|Bacilli,1ZDZ8@1386|Bacillus 91061|Bacilli I Belongs to the phospholipase D family. Cardiolipin synthase subfamily clsB - - ko:K06131 ko00564,ko01100,map00564,map01100 - R07390 RC00017 ko00000,ko00001,ko01000 - - - PLDc_2 k141_14612_1 218284.CCDN010000001_gene1811 6.12e-52 171.0 COG2720@1|root,COG2720@2|Bacteria,1TSH8@1239|Firmicutes,4HCPD@91061|Bacilli,1ZBNK@1386|Bacillus 91061|Bacilli V vancomycin resistance protein yoaR - - - - - - - - - - - PG_binding_4,VanW k141_9926_1 1294265.JCM21738_4364 2.67e-133 379.0 COG1825@1|root,COG1825@2|Bacteria,1VA38@1239|Firmicutes,4HFVB@91061|Bacilli,1ZQMS@1386|Bacillus 91061|Bacilli J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ctc - - ko:K02897 ko03010,map03010 M00178 - - ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L25p,Ribosomal_TL5_C k141_37163_1 744979.R2A130_0094 5.14e-31 121.0 COG0491@1|root,COG0491@2|Bacteria,1MY6G@1224|Proteobacteria,2TTBX@28211|Alphaproteobacteria 28211|Alphaproteobacteria S COG0491 Zn-dependent hydrolases, including glyoxylases - - - - - - - - - - - - Lactamase_B k141_13562_1 1116375.VEJY3_03160 0.0 1030.0 COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,1RNQD@1236|Gammaproteobacteria,1XSY2@135623|Vibrionales 135623|Vibrionales H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) dxs GO:0003674,GO:0003824,GO:0006629,GO:0006720,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008614,GO:0008615,GO:0008661,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016744,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0042816,GO:0042819,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.2.1.7 ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 M00096 R05636 RC00032 ko00000,ko00001,ko00002,ko01000 - - - DXP_synthase_N,Transket_pyr,Transketolase_C k141_13562_2 223926.28805671 4.57e-118 337.0 COG1267@1|root,COG1267@2|Bacteria,1MZJA@1224|Proteobacteria,1S68A@1236|Gammaproteobacteria,1XTFB@135623|Vibrionales 135623|Vibrionales I Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) pgpA - 3.1.3.27 ko:K01095 ko00564,ko01100,map00564,map01100 - R02029 RC00017 ko00000,ko00001,ko01000 - - - PgpA k141_13562_3 1116375.VEJY3_03150 1.55e-175 493.0 COG0611@1|root,COG0611@2|Bacteria,1MU9X@1224|Proteobacteria,1RNHU@1236|Gammaproteobacteria,1XTKW@135623|Vibrionales 135623|Vibrionales F Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 thiL - 2.7.4.16 ko:K00946 ko00730,ko01100,map00730,map01100 M00127 R00617 RC00002 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C k141_19397_2 223926.28808928 3.15e-172 485.0 COG1597@1|root,COG1597@2|Bacteria,1MY37@1224|Proteobacteria,1RMX9@1236|Gammaproteobacteria,1XW60@135623|Vibrionales 135623|Vibrionales F the in vivo substrate is - - - - - - - - - - - - DAGK_cat k141_19397_3 1116375.VEJY3_19081 1.12e-138 407.0 COG2176@1|root,COG2176@2|Bacteria,1MUZD@1224|Proteobacteria,1RPGP@1236|Gammaproteobacteria,1XUHP@135623|Vibrionales 135623|Vibrionales L VRR_NUC - - - - - - - - - - - - VRR_NUC k141_18266_1 218284.CCDN010000005_gene3228 3.94e-137 421.0 COG3857@1|root,COG3857@2|Bacteria,1TQJW@1239|Firmicutes,4HAY6@91061|Bacilli,1ZC70@1386|Bacillus 91061|Bacilli L ATP-dependent helicase deoxyribonuclease subunit B rexB GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0004527,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.6.4.12 ko:K16899 - - - - ko00000,ko01000,ko03400 - - - Exonuc_V_gamma,PDDEXK_1,UvrD_C k141_12385_1 1042377.AFPJ01000009_gene221 2.45e-66 226.0 COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,1RPC6@1236|Gammaproteobacteria,46518@72275|Alteromonadaceae 1236|Gammaproteobacteria L UvrD-like helicase C-terminal domain addA - - - - - - - - - - - PDDEXK_1,UvrD-helicase,UvrD_C k141_23040_2 1280001.BAOA01000009_gene4144 7.14e-167 468.0 COG2853@1|root,COG2853@2|Bacteria,1MVX0@1224|Proteobacteria,1RNPS@1236|Gammaproteobacteria,1XV65@135623|Vibrionales 135623|Vibrionales M COG2853 Surface lipoprotein vacJ - - ko:K04754 - - - - ko00000 - - - MlaA k141_23040_3 1116375.VEJY3_11410 1.44e-27 108.0 COG4235@1|root,COG4235@2|Bacteria,1MY4J@1224|Proteobacteria,1RZEA@1236|Gammaproteobacteria,1XSCF@135623|Vibrionales 135623|Vibrionales O COG4235 Cytochrome c biogenesis factor ccmI - - - - - - - - - - - TPR_19 k141_9927_1 631454.N177_0756 1.11e-11 62.8 COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,2U749@28211|Alphaproteobacteria,1JNXS@119043|Rhodobiaceae 28211|Alphaproteobacteria J Ribosomal protein L17 rplQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02879 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L17 k141_9927_2 1144275.COCOR_02311 2.59e-18 86.7 COG1651@1|root,COG1651@2|Bacteria 2|Bacteria O Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - - - - - - - - - - - Thioredoxin_4 k141_17022_1 1294265.JCM21738_3462 1.6e-28 109.0 COG1158@1|root,COG1158@2|Bacteria,1TPHZ@1239|Firmicutes,4H9XB@91061|Bacilli,1ZBN9@1386|Bacillus 91061|Bacilli K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template rho - - ko:K03628 ko03018,map03018 - - - ko00000,ko00001,ko03019,ko03021 - - - ATP-synt_ab,Rho_N,Rho_RNA_bind k141_37164_1 398767.Glov_2400 4.65e-50 173.0 COG1775@1|root,COG1775@2|Bacteria,1NKED@1224|Proteobacteria,430HE@68525|delta/epsilon subdivisions,2WVZI@28221|Deltaproteobacteria,43V4N@69541|Desulfuromonadales 28221|Deltaproteobacteria E 2-hydroxyglutaryl-CoA dehydratase, D-component - - 1.3.7.8 ko:K04113 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00541 R02451 RC00002,RC01839 ko00000,ko00001,ko00002,ko01000 - - - HGD-D k141_1525_1 985762.SAGN_03290 6.11e-72 228.0 COG0343@1|root,COG0343@2|Bacteria,1TNZ4@1239|Firmicutes,4HCNM@91061|Bacilli,4GYCJ@90964|Staphylococcaceae 91061|Bacilli F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) tgt GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 ko:K00773 - - R03789,R10209 RC00063 ko00000,ko01000,ko03016 - - - TGT k141_5127_1 1279017.AQYJ01000029_gene3689 6.29e-26 111.0 COG0501@1|root,COG0501@2|Bacteria,1NAW7@1224|Proteobacteria,1SFEN@1236|Gammaproteobacteria,46C96@72275|Alteromonadaceae 1236|Gammaproteobacteria O Belongs to the peptidase M48B family - - - - - - - - - - - - Peptidase_M48 k141_5127_2 1279017.AQYJ01000029_gene3688 4.28e-77 238.0 COG1309@1|root,COG1309@2|Bacteria,1RGJ3@1224|Proteobacteria,1S2ZZ@1236|Gammaproteobacteria,46AWF@72275|Alteromonadaceae 1236|Gammaproteobacteria K Bacterial regulatory proteins, tetR family pfiT - - - - - - - - - - - TetR_C_4,TetR_N k141_26732_1 111780.Sta7437_0745 2.48e-42 149.0 COG2135@1|root,COG2135@2|Bacteria,1G1SA@1117|Cyanobacteria,3VK4S@52604|Pleurocapsales 1117|Cyanobacteria S Belongs to the SOS response-associated peptidase family - - - - - - - - - - - - SRAP k141_26732_2 265729.GS18_0208895 4.45e-19 80.9 2E2C2@1|root,32XH4@2|Bacteria,1VDJY@1239|Firmicutes,4HMBA@91061|Bacilli,1ZIXP@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2535) ypmP - - - - - - - - - - - DUF2535 k141_18287_2 1279017.AQYJ01000025_gene619 0.0 921.0 COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria,465QV@72275|Alteromonadaceae 1236|Gammaproteobacteria V Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation msbA GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006855,GO:0006869,GO:0008144,GO:0008150,GO:0008289,GO:0008559,GO:0009987,GO:0010876,GO:0015221,GO:0015238,GO:0015399,GO:0015405,GO:0015437,GO:0015893,GO:0015920,GO:0016020,GO:0016021,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0034040,GO:0034204,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0042626,GO:0042802,GO:0042908,GO:0042910,GO:0043167,GO:0043168,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0061024,GO:0065007,GO:0065008,GO:0071702,GO:0071840,GO:0071944,GO:0097035,GO:0097159,GO:0097367,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901265,GO:1901363,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - ko:K11085 ko02010,map02010 - - - ko00000,ko00001,ko01000,ko02000 3.A.1.106 - iJN746.PP_4935,iPC815.YPO1395,iUMN146_1321.UM146_12980 ABC_membrane,ABC_tran k141_13601_1 218284.CCDN010000001_gene449 3.76e-87 282.0 COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,4HAFP@91061|Bacilli,1ZBJ3@1386|Bacillus 91061|Bacilli V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran k141_37178_1 223926.28809313 5.58e-57 179.0 COG2863@1|root,COG2863@2|Bacteria,1N7W9@1224|Proteobacteria,1S90Z@1236|Gammaproteobacteria,1XYFZ@135623|Vibrionales 135623|Vibrionales C COG2863 Cytochrome c553 - - - - - - - - - - - - Cytochrom_C k141_37178_2 223926.28809312 4.26e-226 624.0 COG2008@1|root,COG2008@2|Bacteria,1MWCR@1224|Proteobacteria,1RNYX@1236|Gammaproteobacteria,1XV3M@135623|Vibrionales 135623|Vibrionales E COG2008 Threonine aldolase ltaE - 4.1.2.48 ko:K01620 ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230 - R00751,R06171 RC00312,RC00372 ko00000,ko00001,ko01000 - - - Beta_elim_lyase k141_37178_3 223926.28809311 2.06e-106 309.0 COG0494@1|root,COG0494@2|Bacteria,1RCX7@1224|Proteobacteria,1RSM2@1236|Gammaproteobacteria,1XX52@135623|Vibrionales 135623|Vibrionales L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - 3.6.1.13 ko:K01515 ko00230,map00230 - R01054 RC00002 ko00000,ko00001,ko01000 - - - NUDIX k141_37178_4 1116375.VEJY3_19481 0.0 1031.0 COG0714@1|root,COG0714@2|Bacteria,1PC08@1224|Proteobacteria,1RQ5U@1236|Gammaproteobacteria,1XSDT@135623|Vibrionales 135623|Vibrionales S COG0714 MoxR-like ATPases ravA - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_5,DUF3763 k141_37178_5 1116375.VEJY3_19486 0.0 924.0 COG2425@1|root,COG2425@2|Bacteria,1N1RQ@1224|Proteobacteria,1RPQT@1236|Gammaproteobacteria,1XTJ0@135623|Vibrionales 135623|Vibrionales S protein containing a von Willebrand factor type A (vWA) domain yieM - - - - - - - - - - - VWA_CoxE k141_21919_1 218284.CCDN010000002_gene2223 4.22e-173 500.0 COG0840@1|root,COG0840@2|Bacteria,1V0SD@1239|Firmicutes,4HD8P@91061|Bacilli,1ZCT0@1386|Bacillus 91061|Bacilli NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - MCPsignal k141_5371_2 1504981.KO116_2021 4.26e-37 132.0 COG0800@1|root,COG0800@2|Bacteria,1RD0T@1224|Proteobacteria,1RQMK@1236|Gammaproteobacteria,1XPFW@135619|Oceanospirillales 135619|Oceanospirillales G Aldolase - - 4.1.2.21 ko:K01631 ko00052,ko01100,map00052,map01100 M00552 R01064 RC00307,RC00435 ko00000,ko00001,ko00002,ko01000 - - - Aldolase k141_11324_1 42256.RradSPS_2491 8.4e-61 195.0 COG0428@1|root,COG0428@2|Bacteria 2|Bacteria P transporter - - - - - - - - - - - - Zip k141_2861_1 1453501.JELR01000002_gene499 2.04e-99 292.0 COG0454@1|root,COG0456@2|Bacteria,1RHB7@1224|Proteobacteria,1S3TD@1236|Gammaproteobacteria,467KA@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases ectA GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016407,GO:0016740,GO:0016746,GO:0016747,GO:0018130,GO:0019491,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0042399,GO:0043170,GO:0043412,GO:0043436,GO:0043543,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.3.1.178 ko:K06718 ko00260,ko01100,ko01120,map00260,map01100,map01120 M00033 R06978 RC00004,RC00096 ko00000,ko00001,ko00002,ko01000 - - - Acetyltransf_1 k141_32496_2 1294265.JCM21738_2721 4.6e-58 181.0 2E309@1|root,32Y0U@2|Bacteria,1VEZC@1239|Firmicutes,4HNYA@91061|Bacilli,1ZQK1@1386|Bacillus 91061|Bacilli S YlaH-like protein - - - - - - - - - - - - YlaH k141_21920_1 42565.FP66_11765 2.06e-119 347.0 COG0435@1|root,COG0435@2|Bacteria,1MV50@1224|Proteobacteria,1RMTI@1236|Gammaproteobacteria,1XI2Z@135619|Oceanospirillales 135619|Oceanospirillales O Glutathione S-transferase - - 1.8.5.7 ko:K07393 - - - - ko00000,ko01000 - - - GST_C_2,GST_N_2 k141_36084_1 1453501.JELR01000001_gene2508 4.84e-27 110.0 28IUR@1|root,2Z8TE@2|Bacteria,1NW7C@1224|Proteobacteria,1RP4W@1236|Gammaproteobacteria,465G0@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_15957_1 1196031.ALEG01000005_gene5543 1.82e-08 60.5 2BCUG@1|root,326F1@2|Bacteria,1V8P9@1239|Firmicutes,4HYG5@91061|Bacilli,1ZHBA@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_33838_1 1294265.JCM21738_398 8.67e-90 271.0 COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,4HAG5@91061|Bacilli,1ZCUX@1386|Bacillus 91061|Bacilli L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage recA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009292,GO:0009294,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0050896,GO:0051704,GO:0051716,GO:0071496 - ko:K03553 ko03440,map03440 M00729 - - ko00000,ko00001,ko00002,ko03400 - - - RecA k141_17135_2 1121938.AUDY01000011_gene596 1.71e-23 94.4 COG2120@1|root,COG2120@2|Bacteria,1UZDV@1239|Firmicutes,4HE79@91061|Bacilli 91061|Bacilli S GlcNAc-PI de-N-acetylase - - - - - - - - - - - - PIG-L k141_14728_2 218284.CCDN010000001_gene1278 1.22e-93 286.0 COG4145@1|root,COG4145@2|Bacteria,1TQ1F@1239|Firmicutes,4HBKD@91061|Bacilli,1ZANP@1386|Bacillus 91061|Bacilli H Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family panF - - ko:K14392 - - - - ko00000,ko02000 2.A.21.1 - - SSF k141_678_1 1246484.D479_02657 1.66e-42 147.0 COG1230@1|root,COG1230@2|Bacteria,1TR92@1239|Firmicutes,4HBCQ@91061|Bacilli,3NEHQ@45667|Halobacillus 91061|Bacilli P Cation efflux family czcD - - ko:K16264 - - - - ko00000,ko02000 2.A.4.1 - - Cation_efflux,ZT_dimer k141_678_2 1034347.CAHJ01000029_gene3562 1.07e-64 202.0 2B3H9@1|root,345WB@2|Bacteria,1W0M6@1239|Firmicutes,4HYK2@91061|Bacilli,1ZFP0@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_18466_1 218284.CCDN010000005_gene3317 7.62e-74 226.0 COG2323@1|root,COG2323@2|Bacteria,1UYR2@1239|Firmicutes,4HFCN@91061|Bacilli,1ZFK2@1386|Bacillus 91061|Bacilli S membrane yetF - - - - - - - - - - - DUF421 k141_10160_1 674977.VMC_17170 6.72e-87 256.0 COG2166@1|root,COG2166@2|Bacteria,1RI8F@1224|Proteobacteria,1S65C@1236|Gammaproteobacteria,1XX28@135623|Vibrionales 135623|Vibrionales S COG2166 SufE protein probably involved in Fe-S center assembly csdE - - ko:K02426 - - - - ko00000 - - - SufE k141_10160_2 1280001.BAOA01000081_gene2932 1.02e-189 527.0 COG1179@1|root,COG1179@2|Bacteria,1MWXR@1224|Proteobacteria,1RMT3@1236|Gammaproteobacteria,1XSUQ@135623|Vibrionales 135623|Vibrionales H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 ygdL - - ko:K22132 - - - - ko00000,ko03016 - - - ThiF k141_10160_3 1116375.VEJY3_12320 5.98e-241 665.0 COG2821@1|root,COG2821@2|Bacteria,1MXD4@1224|Proteobacteria,1RP7K@1236|Gammaproteobacteria,1XTDJ@135623|Vibrionales 135623|Vibrionales M membrane-bound lytic murein transglycosylase mltA GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009253,GO:0030203,GO:0043170,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - ko:K08304 - - - - ko00000,ko01000,ko01011 - GH102 - 3D,MltA k141_7605_1 218284.CCDN010000005_gene3207 5.97e-111 330.0 COG3493@1|root,COG3493@2|Bacteria,1TR97@1239|Firmicutes,4HBS8@91061|Bacilli,1ZC12@1386|Bacillus 91061|Bacilli C COG3493 Na citrate symporter mleP - - - - - - - - - - - 2HCT k141_35040_1 218284.CCDN010000001_gene1055 1.34e-09 57.0 COG1386@1|root,COG1386@2|Bacteria,1V6HI@1239|Firmicutes,4HIQ0@91061|Bacilli,1ZFNU@1386|Bacillus 91061|Bacilli D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves scpB GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K06024 - - - - ko00000,ko03036 - - - SMC_ScpB k141_21921_1 1380390.JIAT01000010_gene4038 1.01e-63 208.0 COG0520@1|root,COG0520@2|Bacteria,2GN15@201174|Actinobacteria,4CS3P@84995|Rubrobacteria 84995|Rubrobacteria E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine - - - - - - - - - - - - - k141_19590_1 1274524.BSONL12_04614 4.07e-203 577.0 COG5362@1|root,COG5410@1|root,COG5362@2|Bacteria,COG5410@2|Bacteria,1TSQB@1239|Firmicutes,4HEZU@91061|Bacilli,1ZBBB@1386|Bacillus 91061|Bacilli S TIGRFAM Phage - - - - - - - - - - - - Terminase_6C k141_13779_1 1042377.AFPJ01000032_gene2724 7.83e-131 386.0 COG1231@1|root,COG1231@2|Bacteria,1PN11@1224|Proteobacteria,1SXFQ@1236|Gammaproteobacteria,46CCE@72275|Alteromonadaceae 1236|Gammaproteobacteria E Flavin containing amine oxidoreductase - - 1.4.3.4 ko:K00274 ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034 M00135 R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354 RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713 ko00000,ko00001,ko00002,ko01000 - - - Amino_oxidase k141_23245_1 42565.FP66_00960 1.2e-77 239.0 COG2199@1|root,COG3706@2|Bacteria,1RBKK@1224|Proteobacteria,1S2QB@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - GGDEF k141_32498_1 1223410.KN050846_gene1419 5.1e-24 103.0 COG3174@1|root,COG3174@2|Bacteria,4NKP6@976|Bacteroidetes,1HYVZ@117743|Flavobacteriia 976|Bacteroidetes S Domain of unknown function (DUF4010) - - - - - - - - - - - - DUF4010,MgtC k141_26923_2 1116375.VEJY3_19811 3.91e-43 144.0 COG0589@1|root,COG0589@2|Bacteria,1MV6Y@1224|Proteobacteria,1RQQ7@1236|Gammaproteobacteria,1Y0V3@135623|Vibrionales 135623|Vibrionales T Universal stress protein family - - - ko:K06149 - - - - ko00000 - - - Usp k141_37334_1 582402.Hbal_1072 3.38e-05 46.2 COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria,1MVU6@1224|Proteobacteria,2TS0R@28211|Alphaproteobacteria,43X9R@69657|Hyphomonadaceae 28211|Alphaproteobacteria C Electron transfer flavoprotein-ubiquinone oxidoreductase etf - 1.5.5.1 ko:K00311 - - - - ko00000,ko01000 - - - ETF_QO,FAD_binding_2,NAD_binding_8 k141_37334_2 1123368.AUIS01000007_gene2733 6.62e-57 202.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,2NBWY@225057|Acidithiobacillales 225057|Acidithiobacillales V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran k141_11354_1 1294265.JCM21738_1745 2.93e-120 349.0 COG4294@1|root,COG4294@2|Bacteria,1TTCB@1239|Firmicutes,4H9PY@91061|Bacilli,1ZCJ7@1386|Bacillus 91061|Bacilli L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion uvsE - - ko:K13281 - - - - ko00000,ko01000 - - - UvdE k141_25644_1 1042377.AFPJ01000025_gene601 3.77e-48 161.0 COG0720@1|root,COG0720@2|Bacteria,1MXVT@1224|Proteobacteria,1RN6H@1236|Gammaproteobacteria,464QP@72275|Alteromonadaceae 1236|Gammaproteobacteria H COG0720 6-pyruvoyl-tetrahydropterin synthase SO2179 - 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 - - - PTPS k141_4165_1 1280001.BAOA01000021_gene848 1.73e-178 512.0 COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,1RMVN@1236|Gammaproteobacteria,1XSTB@135623|Vibrionales 135623|Vibrionales M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source glmS GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 - R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 - - - GATase_6,SIS k141_4165_2 1219076.N646_2546 5.98e-165 463.0 COG1349@1|root,COG1349@2|Bacteria,1MUJG@1224|Proteobacteria,1RNW4@1236|Gammaproteobacteria,1XT3D@135623|Vibrionales 135623|Vibrionales K COG1349 Transcriptional regulators of sugar metabolism srlR - - - - - - - - - - - DeoRC,HTH_DeoR k141_4165_3 223926.28805339 0.0 882.0 COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,1RMW3@1236|Gammaproteobacteria,1XU2Y@135623|Vibrionales 135623|Vibrionales G Belongs to the pyruvate kinase family pykF - 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - PK,PK_C k141_4165_4 29495.EA26_02720 6.43e-98 286.0 COG0440@1|root,COG0440@2|Bacteria,1RAGN@1224|Proteobacteria,1S20I@1236|Gammaproteobacteria,1XTRE@135623|Vibrionales 135623|Vibrionales E COG0440 Acetolactate synthase, small (regulatory) subunit ilvH - 2.2.1.6 ko:K01653 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - ACT,ACT_5,ALS_ss_C k141_4165_5 1116375.VEJY3_01720 0.0 1117.0 COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,1RMQQ@1236|Gammaproteobacteria,1XSYI@135623|Vibrionales 135623|Vibrionales H COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase ilvI - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N k141_4165_6 223926.28805334 0.0 1109.0 COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,1RPNE@1236|Gammaproteobacteria,1XUTB@135623|Vibrionales 135623|Vibrionales I COG1022 Long-chain acyl-CoA synthetases (AMP-forming) - - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding k141_4165_7 223926.28805333 4.57e-218 603.0 COG0583@1|root,COG0583@2|Bacteria,1MX24@1224|Proteobacteria,1RQP0@1236|Gammaproteobacteria,1XV0S@135623|Vibrionales 135623|Vibrionales K Transcriptional regulator leuO - - ko:K05798 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate k141_4165_8 1116375.VEJY3_01705 1.06e-233 645.0 COG4671@1|root,COG4671@2|Bacteria,1QUFP@1224|Proteobacteria,1T1XC@1236|Gammaproteobacteria,1XTDK@135623|Vibrionales 135623|Vibrionales S COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase - - - - - - - - - - - - Glyco_trans_1_3 k141_4165_9 1116375.VEJY3_01700 8.2e-112 323.0 COG0671@1|root,COG0671@2|Bacteria,1RJ1T@1224|Proteobacteria,1SAU1@1236|Gammaproteobacteria,1XWVF@135623|Vibrionales 135623|Vibrionales I COG0671 Membrane-associated phospholipid phosphatase - - 3.6.1.27 ko:K19302 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - PAP2 k141_4165_10 1116375.VEJY3_01695 2.45e-131 379.0 COG4520@1|root,COG4520@2|Bacteria,1QXDK@1224|Proteobacteria,1SVJT@1236|Gammaproteobacteria,1XX83@135623|Vibrionales 135623|Vibrionales M Bacterial SH3 domain - - - - - - - - - - - - SH3_3 k141_4165_11 1219076.N646_2534 0.0 991.0 COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,1RMWE@1236|Gammaproteobacteria,1XSXP@135623|Vibrionales 135623|Vibrionales E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) leuA GO:0003674,GO:0003824,GO:0003852,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046912,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.3.13 ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 M00432 R01213 RC00004,RC00470,RC02754 br01601,ko00000,ko00001,ko00002,ko01000 - - - HMGL-like,LeuA_dimer k141_4165_12 674977.VMC_03240 1.3e-198 553.0 COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,1RMZQ@1236|Gammaproteobacteria,1XTG7@135623|Vibrionales 135623|Vibrionales CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate leuB GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R00994,R04426,R10052 RC00084,RC00417,RC03036 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh k141_19616_1 1120953.AUBH01000004_gene2977 8.61e-154 460.0 2EXJW@1|root,33QVY@2|Bacteria,1QSMJ@1224|Proteobacteria,1SK5H@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_19616_2 1120953.AUBH01000004_gene2976 4.73e-62 198.0 2BN4A@1|root,32GR8@2|Bacteria,1RHQ4@1224|Proteobacteria,1S86P@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_18495_1 1118054.CAGW01000025_gene527 2.39e-70 224.0 COG3844@1|root,COG3844@2|Bacteria,1TQ8V@1239|Firmicutes,4HBE8@91061|Bacilli,26TGS@186822|Paenibacillaceae 91061|Bacilli E Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively kynU - 3.7.1.3 ko:K01556 ko00380,ko01100,map00380,map01100 M00038 R00987,R02668,R03936 RC00284,RC00415 ko00000,ko00001,ko00002,ko01000 - - - Aminotran_5 k141_18495_2 1294265.JCM21738_2511 1.09e-40 140.0 COG3483@1|root,COG3483@2|Bacteria,1TR14@1239|Firmicutes,4H9X1@91061|Bacilli,1ZBYU@1386|Bacillus 91061|Bacilli E Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety kynA GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019752,GO:0020037,GO:0022607,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.11 ko:K00453 ko00380,ko01100,map00380,map01100 M00038 R00678 RC00356 ko00000,ko00001,ko00002,ko01000 - - - Trp_dioxygenase k141_1655_1 493475.GARC_4043 8.12e-41 145.0 COG0412@1|root,COG0412@2|Bacteria 2|Bacteria Q carboxymethylenebutenolidase activity M1-673 - 3.1.1.45 ko:K01061,ko:K07017 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 - R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222 RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 - - - DLH k141_1655_2 493475.GARC_4042 3.79e-55 176.0 COG0824@1|root,COG0824@2|Bacteria,1N8J9@1224|Proteobacteria 1224|Proteobacteria S Thioesterase-like superfamily - - - ko:K07107 - - - - ko00000,ko01000 - - - 4HBT,4HBT_2 k141_1655_3 1453501.JELR01000006_gene2 2.75e-67 213.0 COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,1RMSS@1236|Gammaproteobacteria,4651Y@72275|Alteromonadaceae 1236|Gammaproteobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_int_SAM_4,Phage_integrase k141_5406_1 1294265.JCM21738_1165 1.14e-37 137.0 COG0477@1|root,COG2814@2|Bacteria,1TQ7H@1239|Firmicutes,4HB0I@91061|Bacilli,1ZS7F@1386|Bacillus 91061|Bacilli EGP Major Facilitator Superfamily ydeG3 - - - - - - - - - - - MFS_1,MFS_2,Sugar_tr k141_696_2 218284.CCDN010000002_gene2888 4.66e-109 322.0 COG0609@1|root,COG0609@2|Bacteria,1TPX6@1239|Firmicutes,4HAM8@91061|Bacilli,1ZAU0@1386|Bacillus 91061|Bacilli P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily fhuG - - ko:K02015 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - FecCD k141_27736_1 1453501.JELR01000001_gene3264 5.74e-114 344.0 COG0204@1|root,COG0204@2|Bacteria,1MWDY@1224|Proteobacteria,1RRXF@1236|Gammaproteobacteria,464IC@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG0477 Permeases of the major facilitator superfamily aas - 2.3.1.40,6.2.1.20 ko:K05939 ko00071,ko00564,map00071,map00564 - R01406,R04864 RC00014,RC00039,RC00041 ko00000,ko00001,ko01000 - - - Acyltransferase,MFS_1 k141_2879_1 218284.CCDN010000002_gene2165 3.49e-105 321.0 COG0025@1|root,COG0025@2|Bacteria,1U8X3@1239|Firmicutes,4HBQR@91061|Bacilli,1ZQCD@1386|Bacillus 91061|Bacilli P Sodium/hydrogen exchanger family - - - - - - - - - - - - Na_H_Exchanger,TrkA_N k141_7620_1 218284.CCDN010000001_gene922 9.93e-49 186.0 COG0419@1|root,COG4733@1|root,COG0419@2|Bacteria,COG4733@2|Bacteria,1TQWP@1239|Firmicutes,4HEU7@91061|Bacilli,1ZF79@1386|Bacillus 91061|Bacilli L Phage minor structural protein - - - - - - - - - - - - Prophage_tail k141_8952_1 665959.HMPREF1013_04971 3.01e-140 409.0 COG3634@1|root,COG3634@2|Bacteria,1TPYN@1239|Firmicutes,4H9W1@91061|Bacilli,1ZCRN@1386|Bacillus 91061|Bacilli O Alkyl hydroperoxide reductase ahpF - - ko:K03387 - - - - ko00000,ko01000 - - - Pyr_redox_2,Thioredoxin_3 k141_17161_1 1116375.VEJY3_19211 7.66e-100 305.0 COG3290@1|root,COG3290@2|Bacteria,1MXQ5@1224|Proteobacteria,1RNRF@1236|Gammaproteobacteria,1XW6Z@135623|Vibrionales 135623|Vibrionales T Single cache domain 3 - - 2.7.13.3 ko:K07700 ko02020,map02020 M00486 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c_5,SPOB_a,sCache_3_2 k141_30141_1 218284.CCDN010000005_gene3177 1.02e-63 196.0 COG4980@1|root,COG4980@2|Bacteria,1VAKP@1239|Firmicutes,4HKD5@91061|Bacilli,1ZJ3D@1386|Bacillus 91061|Bacilli S YtxH-like protein yhaH - - - - - - - - - - - YtxH k141_15983_1 1078085.HMPREF1210_03094 2.82e-186 536.0 COG4585@1|root,COG4585@2|Bacteria,1V3N2@1239|Firmicutes,4HHKF@91061|Bacilli,26GPX@186818|Planococcaceae 91061|Bacilli T Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - - - - - - - - - - GAF,HATPase_c,HisKA_3 k141_1656_1 218284.CCDN010000001_gene1340 9.19e-97 288.0 COG0714@1|root,COG0714@2|Bacteria,1TQJA@1239|Firmicutes,4HBG4@91061|Bacilli,1ZAT6@1386|Bacillus 91061|Bacilli S ATPase family associated with various cellular activities (AAA) yojN - - ko:K04748 - - R00294 RC02794 ko00000 3.D.4.10 - - AAA_5,CbbQ_C k141_1656_2 441769.ABFU01000028_gene1244 2.51e-09 53.1 COG4548@1|root,COG4548@2|Bacteria 2|Bacteria P von Willebrand factor (vWF) type A domain - - - - - - - - - - - - CobT_C,VWA k141_25646_1 218284.CCDN010000001_gene1676 5.92e-60 191.0 COG4336@1|root,COG4336@2|Bacteria,1TRY8@1239|Firmicutes,4HCWD@91061|Bacilli,1ZB87@1386|Bacillus 91061|Bacilli S Belongs to the D-glutamate cyclase family ycsI - - - - - - - - - - - DUF1445 k141_12622_1 1444770.AF72_05090 2.75e-06 54.3 COG0773@1|root,COG0773@2|Bacteria,1MUC5@1224|Proteobacteria,1RMMT@1236|Gammaproteobacteria,1X4Y7@135614|Xanthomonadales 135614|Xanthomonadales M Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate mpl - 6.3.2.45 ko:K02558 - - - - ko00000,ko01000 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M k141_19618_1 666686.B1NLA3E_20390 2.75e-96 294.0 COG1027@1|root,COG1027@2|Bacteria,1TP3U@1239|Firmicutes,4HFM9@91061|Bacilli,1ZB5F@1386|Bacillus 91061|Bacilli E Aspartate ammonia-lyase aspA - 4.3.1.1 ko:K01744 ko00250,ko01100,map00250,map01100 - R00490 RC00316,RC02799 ko00000,ko00001,ko01000 - - - FumaraseC_C,Lyase_1 k141_24282_1 198467.NP92_14590 2.21e-36 128.0 2BZV8@1|root,30HHG@2|Bacteria,1V68P@1239|Firmicutes,4HHRU@91061|Bacilli 91061|Bacilli S Replication-relaxation - - - - - - - - - - - - Replic_Relax k141_7621_1 713587.THITH_14170 8.91e-23 93.2 COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,1RQ38@1236|Gammaproteobacteria,1WW34@135613|Chromatiales 135613|Chromatiales J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit rpsD - - ko:K02986 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S4,S4 k141_7621_2 1265503.KB905161_gene3407 6.17e-53 176.0 COG0202@1|root,COG0202@2|Bacteria,1MU75@1224|Proteobacteria,1RMU3@1236|Gammaproteobacteria,2Q5TR@267889|Colwelliaceae 1236|Gammaproteobacteria K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoA GO:0003674,GO:0003824,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L k141_5408_1 1453501.JELR01000002_gene1022 1.36e-21 92.4 COG0388@1|root,COG0388@2|Bacteria,1MUUB@1224|Proteobacteria,1RNVZ@1236|Gammaproteobacteria,466U1@72275|Alteromonadaceae 1236|Gammaproteobacteria S amidohydrolase ramA - 3.5.5.1 ko:K01501,ko:K11206 ko00380,ko00460,ko00627,ko00643,ko00910,ko01120,map00380,map00460,map00627,map00643,map00910,map01120 - R00540,R01887,R03093,R03542,R05591,R07855 RC00315,RC00325,RC00617,RC00959,RC02811 ko00000,ko00001,ko01000 - - - CN_hydrolase k141_5408_2 1535422.ND16A_3283 3.47e-20 93.2 COG0823@1|root,COG3710@1|root,COG0823@2|Bacteria,COG3710@2|Bacteria,1RIFT@1224|Proteobacteria,1S7XY@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Transcriptional regulatory protein, C terminal - - - - - - - - - - - - PD40,Trans_reg_C k141_33866_2 84531.JMTZ01000141_gene1679 4.47e-22 94.4 COG1760@1|root,COG1760@2|Bacteria,1MUZN@1224|Proteobacteria,1RMJZ@1236|Gammaproteobacteria,1X3P1@135614|Xanthomonadales 135614|Xanthomonadales E Serine dehydratase sdaA - 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 - R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 - - - SDH_alpha,SDH_beta k141_17162_2 981383.AEWH01000026_gene2843 2.33e-25 105.0 COG3104@1|root,COG3104@2|Bacteria,1TP81@1239|Firmicutes,4HAF2@91061|Bacilli 91061|Bacilli E transporter - - - ko:K03305 - - - - ko00000 2.A.17 - - PTR2 k141_10193_1 218284.CCDN010000001_gene610 8.88e-88 272.0 COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,4HBJM@91061|Bacilli,1ZAWN@1386|Bacillus 91061|Bacilli H Belongs to the folylpolyglutamate synthase family folC GO:0003674,GO:0003824,GO:0004326,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006761,GO:0006807,GO:0008150,GO:0008152,GO:0008841,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046452,GO:0046483,GO:0046900,GO:0046901,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 - - - Mur_ligase_C,Mur_ligase_M k141_1657_1 406124.ACPC01000008_gene1648 1.58e-82 259.0 COG0591@1|root,COG0591@2|Bacteria,1TPVE@1239|Firmicutes,4H9KW@91061|Bacilli,1ZB64@1386|Bacillus 91061|Bacilli E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family putP - - ko:K03307,ko:K11928 - - - - ko00000,ko02000 2.A.21,2.A.21.2 - - SSF k141_698_1 218284.CCDN010000004_gene3150 8.72e-137 396.0 COG0189@1|root,COG0189@2|Bacteria,1UZ79@1239|Firmicutes,4HTI1@91061|Bacilli,1ZBQZ@1386|Bacillus 91061|Bacilli HJ COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase) - - - - - - - - - - - - ATPgrasp_YheCD k141_30142_1 1294265.JCM21738_3231 2e-107 317.0 COG0668@1|root,COG0668@2|Bacteria,1TR9Z@1239|Firmicutes,4HCB8@91061|Bacilli,1ZCW4@1386|Bacillus 91061|Bacilli M Mechanosensitive ion channel ykuT - - ko:K22044 - - - - ko00000,ko02000 1.A.23.3 - - MS_channel k141_11357_1 1236973.JCM9157_2170 2.42e-27 108.0 COG2256@1|root,COG2256@2|Bacteria,1TPVV@1239|Firmicutes,4HAIS@91061|Bacilli,1ZBCW@1386|Bacillus 91061|Bacilli L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase rarA - - ko:K07478 - - - - ko00000 - - - AAA,AAA_assoc_2,MgsA_C,RuvB_N k141_18496_1 218284.CCDN010000003_gene2995 1.52e-39 139.0 2BYDV@1|root,32RAH@2|Bacteria,1V91M@1239|Firmicutes,4HIIQ@91061|Bacilli,1ZH7H@1386|Bacillus 91061|Bacilli S spore cortex biosynthesis protein yabQ GO:0005575,GO:0005623,GO:0042601,GO:0042763,GO:0044464 - - - - - - - - - - Spore_YabQ k141_29044_1 1274524.BSONL12_04369 5.44e-23 99.8 COG0305@1|root,COG0305@2|Bacteria,1UYF2@1239|Firmicutes,4HF6Q@91061|Bacilli 91061|Bacilli L DnaB-like helicase C terminal domain - - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - AAA_25,DnaB_C k141_29044_3 218284.CCDN010000001_gene1222 4.81e-09 62.0 2ESB9@1|root,33JW0@2|Bacteria,1VMVV@1239|Firmicutes,4HSTZ@91061|Bacilli,1ZD8X@1386|Bacillus 91061|Bacilli - - yodN - - - - - - - - - - - - k141_32529_1 218284.CCDN010000001_gene1586 5.76e-136 391.0 COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,4H9YB@91061|Bacilli,1ZBA4@1386|Bacillus 91061|Bacilli E Belongs to the ABC transporter superfamily ykfD - - ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY k141_13806_2 1279017.AQYJ01000020_gene1252 8.33e-266 733.0 COG2718@1|root,COG2718@2|Bacteria,1MWQM@1224|Proteobacteria,1RQWC@1236|Gammaproteobacteria,464ND@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the UPF0229 family yeaH - - ko:K09786 - - - - ko00000 - - - DUF444 k141_19620_1 42565.FP66_09520 6.11e-107 315.0 COG1354@1|root,COG1354@2|Bacteria,1MVCN@1224|Proteobacteria,1RNBB@1236|Gammaproteobacteria,1XHG7@135619|Oceanospirillales 135619|Oceanospirillales D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves scpA - - ko:K05896 - - - - ko00000,ko03036 - - - SMC_ScpA k141_17163_1 218284.CCDN010000004_gene3044 7.26e-22 94.0 COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,4HACR@91061|Bacilli,1ZCC3@1386|Bacillus 91061|Bacilli M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein murF - 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 - R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M k141_699_1 324057.Pjdr2_0039 1.19e-05 50.1 COG1197@1|root,COG1197@2|Bacteria,1TPF1@1239|Firmicutes,4H9NB@91061|Bacilli,26QY4@186822|Paenibacillaceae 91061|Bacilli L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd - - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF k141_24549_1 406124.ACPC01000042_gene2200 2.65e-128 384.0 COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,4HA1G@91061|Bacilli,1ZASC@1386|Bacillus 91061|Bacilli G COG0366 Glycosidases malL GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.2.1.10 ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00801,R01718,R01791,R06199 RC00028,RC00059,RC00077,RC00451 ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,Malt_amylase_C k141_7811_1 1007105.PT7_0909 9.56e-22 94.4 COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,2VHS3@28216|Betaproteobacteria,3T1EM@506|Alcaligenaceae 28216|Betaproteobacteria H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction thiC - 4.1.99.17 ko:K03147 ko00730,ko01100,map00730,map01100 M00127 R03472 RC03251,RC03252 ko00000,ko00001,ko00002,ko01000 - - - ThiC-associated,ThiC_Rad_SAM k141_16172_1 218284.CCDN010000002_gene2160 1.89e-123 357.0 COG0395@1|root,COG0395@2|Bacteria,1TQG0@1239|Firmicutes,4HD6Q@91061|Bacilli,1ZAVF@1386|Bacillus 91061|Bacilli P PFAM binding-protein-dependent transport systems inner membrane component - - - ko:K02026 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - BPD_transp_1 k141_18754_2 1150626.PHAMO_210277 7.58e-15 78.2 COG3103@1|root,COG4991@2|Bacteria,1QZFM@1224|Proteobacteria,2U7JW@28211|Alphaproteobacteria,2JZNS@204441|Rhodospirillales 204441|Rhodospirillales T sh3 domain protein - - - - - - - - - - - - - k141_17330_1 218284.CCDN010000001_gene1071 6.88e-109 327.0 COG0514@1|root,COG0514@2|Bacteria,1TPN5@1239|Firmicutes,4H9QP@91061|Bacilli,1ZB1X@1386|Bacillus 91061|Bacilli L DNA helicase recQ GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009378,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.6.4.12 ko:K03654 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecQ_Zn_bind k141_24550_1 1033734.CAET01000013_gene1777 1.08e-41 147.0 COG1914@1|root,COG1914@2|Bacteria,1V04N@1239|Firmicutes,4HBF6@91061|Bacilli,1ZF5E@1386|Bacillus 91061|Bacilli P Natural resistance-associated macrophage protein mntH_2 - - - - - - - - - - - Nramp k141_34050_1 981383.AEWH01000060_gene1991 1.05e-90 276.0 COG1957@1|root,COG1957@2|Bacteria,1TRWG@1239|Firmicutes,4HCMZ@91061|Bacilli 91061|Bacilli F nucleoside hydrolase rihA_1 - 3.2.2.1 ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 - R01245,R01273,R01677,R01770,R02143 RC00033,RC00063,RC00122,RC00318,RC00485 ko00000,ko00001,ko01000 - - - IU_nuc_hydro k141_10381_1 797304.Natgr_0190 2.25e-40 140.0 arCOG11504@1|root,arCOG11504@2157|Archaea,2XX31@28890|Euryarchaeota,23VW4@183963|Halobacteria 183963|Halobacteria - - - - - - - - - - - - - - - k141_23471_1 674977.VMC_42120 1.86e-113 333.0 COG0765@1|root,COG0765@2|Bacteria,1MV3I@1224|Proteobacteria,1RPJR@1236|Gammaproteobacteria,1XTN4@135623|Vibrionales 135623|Vibrionales P COG0765 ABC-type amino acid transport system, permease component aapM - - ko:K09971 ko02010,map02010 M00232 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.18,3.A.1.3.7,3.A.1.3.8 - - BPD_transp_1 k141_14939_1 944435.AXAJ01000007_gene1726 1.91e-15 74.7 COG2072@1|root,COG2072@2|Bacteria,1MWPJ@1224|Proteobacteria,2VNXC@28216|Betaproteobacteria,1K5IQ@119060|Burkholderiaceae 28216|Betaproteobacteria P Flavin-binding monooxygenase-like - - 1.14.13.148 ko:K07222,ko:K18277 ko00680,map00680 - R05623 RC00058 ko00000,ko00001,ko01000 - - - FMO-like,Pyr_redox_3,SnoaL_2 k141_14939_2 42565.FP66_04870 7.61e-22 92.0 COG0500@1|root,COG2226@2|Bacteria,1PPKI@1224|Proteobacteria,1S574@1236|Gammaproteobacteria,1XRAR@135619|Oceanospirillales 135619|Oceanospirillales Q ubiE/COQ5 methyltransferase family - - - - - - - - - - - - - k141_24551_1 745411.B3C1_09622 0.000478 43.1 COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria,1J8B4@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O COG1404 Subtilisin-like serine proteases - - - ko:K14645 ko02024,map02024 - - - ko00000,ko00001,ko01000,ko01002,ko03110 - - - Inhibitor_I9,PA,PPC,P_proprotein,Peptidase_S8 k141_12816_2 1294265.JCM21738_3394 1.89e-137 392.0 COG1191@1|root,COG1191@2|Bacteria,1V5E6@1239|Firmicutes,4HEBS@91061|Bacilli,1ZCY4@1386|Bacillus 91061|Bacilli K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released sigI - - ko:K03093 - - - - ko00000,ko03021 - - - Sigma70_r2 k141_29231_1 1453501.JELR01000002_gene342 6.84e-182 583.0 COG1361@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4932@2|Bacteria,1R5G4@1224|Proteobacteria,1SEWA@1236|Gammaproteobacteria,469S7@72275|Alteromonadaceae 1236|Gammaproteobacteria M Domain of unknown function DUF11 - - - - - - - - - - - - DUF11,SdrD_B k141_35300_1 1294265.JCM21738_2765 7.97e-113 331.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,4H9NS@91061|Bacilli,1ZCF9@1386|Bacillus 91061|Bacilli G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family gapB GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016491,GO:0016620,GO:0016903,GO:0019318,GO:0019319,GO:0036094,GO:0043891,GO:0044238,GO:0044281,GO:0044283,GO:0046364,GO:0048037,GO:0050661,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N k141_19791_1 1116375.VEJY3_02950 1.6e-119 346.0 COG4585@1|root,COG4585@2|Bacteria,1MWPN@1224|Proteobacteria,1T1IF@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Histidine kinase - - - - - - - - - - - - 7TMR-DISM_7TM,HATPase_c,HisKA_3,PAS,PAS_4,PAS_9 k141_11586_1 617140.AJZE01000078_gene1847 7.96e-75 240.0 COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,1TFGA@1236|Gammaproteobacteria,1XXNF@135623|Vibrionales 135623|Vibrionales Q Amidohydrolase family - - - - - - - - - - - - Amidohydro_3 k141_32726_1 1123487.KB892868_gene1187 1.45e-113 342.0 COG0714@1|root,COG0714@2|Bacteria,1MXQ2@1224|Proteobacteria,2W10G@28216|Betaproteobacteria 28216|Betaproteobacteria S ATPase family associated with various cellular activities (AAA) - - - - - - - - - - - - AAA_3 k141_9172_1 1033734.CAET01000038_gene281 9.84e-49 157.0 2E4XN@1|root,32ZRM@2|Bacteria,1VG38@1239|Firmicutes,4I8A3@91061|Bacilli,1ZI1M@1386|Bacillus 91061|Bacilli S Belongs to the WXG100 family - - - - - - - - - - - - WXG100 k141_9172_2 1033734.CAET01000038_gene280 8.7e-15 68.6 2BYG9@1|root,33261@2|Bacteria,1VFZJ@1239|Firmicutes,4I8FR@91061|Bacilli,1ZI1H@1386|Bacillus 91061|Bacilli S Proteins of 100 residues with WXG - - - - - - - - - - - - WXG100 k141_23472_2 933262.AXAM01000044_gene1408 5.77e-35 132.0 COG3385@1|root,COG3385@2|Bacteria,1MVRM@1224|Proteobacteria,42U5W@68525|delta/epsilon subdivisions,2WQUQ@28221|Deltaproteobacteria,2MKFC@213118|Desulfobacterales 28221|Deltaproteobacteria L PFAM transposase IS4 family protein - - - - - - - - - - - - DDE_Tnp_1,Nterm_IS4 k141_875_1 218284.CCDN010000001_gene442 6.68e-68 213.0 COG2267@1|root,COG2267@2|Bacteria,1UHRG@1239|Firmicutes,4IS7B@91061|Bacilli,1ZS1J@1386|Bacillus 91061|Bacilli I alpha/beta hydrolase fold - - 3.4.11.5 ko:K01259 ko00330,map00330 - R00135 - ko00000,ko00001,ko01000,ko01002 - - - Abhydrolase_1 k141_875_2 218284.CCDN010000001_gene443 1.03e-17 75.1 COG1878@1|root,COG1878@2|Bacteria,1U21N@1239|Firmicutes,4IBIN@91061|Bacilli,1ZIKG@1386|Bacillus 91061|Bacilli S Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation - - - - - - - - - - - - - k141_27907_1 1116375.VEJY3_12765 1.5e-158 451.0 COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,1RPKC@1236|Gammaproteobacteria,1XVI5@135623|Vibrionales 135623|Vibrionales J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) tyrS GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006437,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - S4,tRNA-synt_1b k141_27907_2 1116375.VEJY3_12770 1.4e-296 811.0 COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,1RM7S@1236|Gammaproteobacteria,1XUZ4@135623|Vibrionales 135623|Vibrionales M COG0739 Membrane proteins related to metalloendopeptidases yebA - - - - - - - - - - - OapA,OapA_N,Peptidase_M23 k141_27907_3 223926.28807470 0.0 1835.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1XU61@135623|Vibrionales 135623|Vibrionales V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K18989 - M00720 - - ko00000,ko00002,ko02000 2.A.6.2.30 - - ACR_tran k141_27907_4 1219076.N646_1569 1.85e-202 568.0 COG0845@1|root,COG0845@2|Bacteria,1MVFN@1224|Proteobacteria,1RNN6@1236|Gammaproteobacteria,1XTRP@135623|Vibrionales 135623|Vibrionales M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K18990 - M00720 - - ko00000,ko00002,ko02000 2.A.6.2.30,8.A.1 - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 k141_27907_5 223926.28807472 1.26e-75 226.0 COG0316@1|root,COG0316@2|Bacteria,1RHCW@1224|Proteobacteria,1S675@1236|Gammaproteobacteria,1XXC1@135623|Vibrionales 135623|Vibrionales C Iron-sulfur cluster insertion protein ErpA erpA GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016226,GO:0019538,GO:0022607,GO:0031163,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0071704,GO:0071840,GO:1901564 - ko:K15724 - - - - ko00000 - - - Fe-S_biosyn k141_27907_6 1280001.BAOA01000059_gene2294 2.23e-174 494.0 COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,1RM7N@1236|Gammaproteobacteria,1XUGV@135623|Vibrionales 135623|Vibrionales H Glutamate-1-semialdehyde aminotransferase hemL GO:0003674,GO:0003824,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016853,GO:0016866,GO:0016869,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 5.4.3.8 ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02272 RC00677 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 k141_23498_1 1453501.JELR01000002_gene1144 1.67e-71 242.0 COG2304@1|root,COG2931@1|root,COG3210@1|root,COG2304@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,1R1GH@1224|Proteobacteria,1T525@1236|Gammaproteobacteria 1236|Gammaproteobacteria U oxidoreductase activity - - - - - - - - - - - - - k141_29258_1 218284.CCDN010000001_gene1775 3.26e-57 206.0 COG0419@1|root,COG0419@2|Bacteria,1TPCS@1239|Firmicutes,4H9Q3@91061|Bacilli,1ZAP5@1386|Bacillus 91061|Bacilli L COG0419 ATPase involved in DNA repair sbcC - - ko:K03546 - - - - ko00000,ko03400 - - - AAA_23,AAA_29,SbcCD_C k141_7831_1 218284.CCDN010000001_gene1712 1.39e-175 494.0 COG0820@1|root,COG0820@2|Bacteria,1TPVF@1239|Firmicutes,4H9NU@91061|Bacilli,1ZBCJ@1386|Bacillus 91061|Bacilli J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs rlmN GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 ko:K06941 - - - - ko00000,ko01000,ko03009 - - - Fer4_14,Radical_SAM k141_22161_1 1453501.JELR01000002_gene1343 3.17e-73 223.0 COG1595@1|root,COG1595@2|Bacteria,1RDTK@1224|Proteobacteria,1S57H@1236|Gammaproteobacteria,466XW@72275|Alteromonadaceae 1236|Gammaproteobacteria K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_22161_2 1453501.JELR01000002_gene1344 1.65e-47 163.0 COG3712@1|root,COG3712@2|Bacteria,1MZCK@1224|Proteobacteria,1S88I@1236|Gammaproteobacteria,467V5@72275|Alteromonadaceae 1236|Gammaproteobacteria PT Domain of unknown function (DUF4880) - - - ko:K07165 - - - - ko00000 - - - DUF4880,DUF4974,FecR k141_23499_1 42565.FP66_11605 4.49e-111 330.0 COG3182@1|root,COG3182@2|Bacteria,1MX8C@1224|Proteobacteria,1RSDV@1236|Gammaproteobacteria,1XK0V@135619|Oceanospirillales 135619|Oceanospirillales S iron-regulated membrane protein - - - - - - - - - - - - PepSY,PepSY_TM k141_5658_1 1232437.KL661961_gene2966 9.97e-33 130.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,42NAV@68525|delta/epsilon subdivisions,2WJ3W@28221|Deltaproteobacteria,2MIIB@213118|Desulfobacterales 28221|Deltaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k141_9185_1 1294265.JCM21738_551 1.05e-99 297.0 COG3595@1|root,COG3595@2|Bacteria,1V94C@1239|Firmicutes,4HJYP@91061|Bacilli,1ZEE4@1386|Bacillus 91061|Bacilli S Putative adhesin liaG - - ko:K11621 ko02020,map02020 - - - ko00000,ko00001 - - - DUF4097 k141_29259_1 1453501.JELR01000001_gene2647 2.4e-139 400.0 COG0385@1|root,COG0385@2|Bacteria,1MXF3@1224|Proteobacteria,1RNZF@1236|Gammaproteobacteria,46A32@72275|Alteromonadaceae 1236|Gammaproteobacteria S SBF-like CPA transporter family (DUF4137) - - - ko:K03453 - - - - ko00000 2.A.28 - - SBF k141_6762_1 218284.CCDN010000001_gene1387 2.23e-156 456.0 COG2905@1|root,COG2905@2|Bacteria,1TQFI@1239|Firmicutes,4HDTM@91061|Bacilli,1ZQQC@1386|Bacillus 91061|Bacilli T Putative nucleotidyltransferase substrate binding domain - - - ko:K07182 - - - - ko00000 - - - CBS,DUF294,DUF294_C,cNMP_binding k141_19817_1 1279017.AQYJ01000029_gene3441 2.42e-58 191.0 COG4977@1|root,COG4977@2|Bacteria,1MUDK@1224|Proteobacteria,1RP9W@1236|Gammaproteobacteria,464RD@72275|Alteromonadaceae 1236|Gammaproteobacteria K DJ-1/PfpI family - - - - - - - - - - - - DJ-1_PfpI,HTH_18 k141_19817_2 1453501.JELR01000001_gene2627 2.03e-60 202.0 COG0304@1|root,COG0304@2|Bacteria,1MV67@1224|Proteobacteria,1RMXJ@1236|Gammaproteobacteria,4660E@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ Beta-ketoacyl synthase, C-terminal domain - - 2.3.1.180 ko:K18473 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt k141_23500_1 1449351.RISW2_15565 2.67e-57 183.0 28HEZ@1|root,32P6N@2|Bacteria,1RJDF@1224|Proteobacteria,2U9XI@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - DnaA_N k141_24575_1 1462526.BN990_02936 3.53e-100 305.0 COG1231@1|root,COG1231@2|Bacteria,1TRJC@1239|Firmicutes,4HBN4@91061|Bacilli 91061|Bacilli E Monoamine oxidase - - 1.4.3.4 ko:K00274 ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034 M00135 R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354 RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713 ko00000,ko00001,ko00002,ko01000 - - - Amino_oxidase k141_31442_1 218284.CCDN010000004_gene3098 3.28e-161 461.0 COG2719@1|root,COG2719@2|Bacteria,1TRHQ@1239|Firmicutes,4HBAW@91061|Bacilli,1ZAT5@1386|Bacillus 91061|Bacilli S Stage V sporulation protein R spoVR - - ko:K06415 - - - - ko00000 - - - SpoVR k141_30293_1 1036674.A28LD_1109 4.16e-137 400.0 COG0753@1|root,COG0753@2|Bacteria,1MUXZ@1224|Proteobacteria,1RNE7@1236|Gammaproteobacteria,2QFWU@267893|Idiomarinaceae 1236|Gammaproteobacteria C Has an organic peroxide-dependent peroxidase activity katE - 1.11.1.6 ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 M00532 R00009,R00602,R02670 RC00034,RC00767,RC02141,RC02755 ko00000,ko00001,ko00002,ko01000 - - - Catalase k141_30293_2 1500890.JQNL01000001_gene3755 1.84e-34 127.0 COG3038@1|root,COG3038@2|Bacteria,1RDYK@1224|Proteobacteria,1S6GR@1236|Gammaproteobacteria,1XCYN@135614|Xanthomonadales 135614|Xanthomonadales C Prokaryotic cytochrome b561 - - - - - - - - - - - - Ni_hydr_CYTB k141_11607_1 218284.CCDN010000001_gene543 1.95e-105 307.0 COG0398@1|root,COG0398@2|Bacteria,1V8XH@1239|Firmicutes,4HJZ2@91061|Bacilli,1ZFKY@1386|Bacillus 91061|Bacilli S SNARE associated Golgi protein - - - - - - - - - - - - SNARE_assoc k141_9186_1 1294265.JCM21738_5435 4.94e-09 55.8 COG0111@1|root,COG0111@2|Bacteria,1TSDK@1239|Firmicutes,4HAW5@91061|Bacilli,1ZCEY@1386|Bacillus 91061|Bacilli EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family ghrA - - - - - - - - - - - 2-Hacid_dh,2-Hacid_dh_C k141_9186_2 1294265.JCM21738_5436 2.79e-124 354.0 COG2096@1|root,COG2096@2|Bacteria,1V3PI@1239|Firmicutes,4HH26@91061|Bacilli,1ZCJ1@1386|Bacillus 91061|Bacilli S Adenosyltransferase yvqK - 2.5.1.17 ko:K00798 ko00860,ko01100,map00860,map01100 M00122 R01492,R05220,R07268 RC00533 ko00000,ko00001,ko00002,ko01000 - - - Cob_adeno_trans k141_32739_1 1116375.VEJY3_12630 8.52e-80 238.0 COG3050@1|root,COG3050@2|Bacteria,1RH2F@1224|Proteobacteria,1S634@1236|Gammaproteobacteria,1XYDF@135623|Vibrionales 135623|Vibrionales L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is holD - 2.7.7.7 ko:K02344 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_III_psi k141_32739_2 1116375.VEJY3_12625 2.43e-96 283.0 COG0454@1|root,COG0456@2|Bacteria,1RIE6@1224|Proteobacteria,1S9G0@1236|Gammaproteobacteria,1XXEY@135623|Vibrionales 135623|Vibrionales K This enzyme acetylates the N-terminal alanine of ribosomal protein S18 rimI - 2.3.1.128 ko:K03789 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_1,Acetyltransf_10 k141_32739_3 1116375.VEJY3_12620 0.0 1048.0 COG4108@1|root,COG4108@2|Bacteria,1MU7X@1224|Proteobacteria,1RMFT@1236|Gammaproteobacteria,1XVAZ@135623|Vibrionales 135623|Vibrionales J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP prfC GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02837 - - - - ko00000,ko03012 - - - GTP_EFTU,GTP_EFTU_D2,RF3_C k141_32739_4 1219076.N646_1534 1.15e-21 85.9 2AWWF@1|root,31NTY@2|Bacteria,1QKI2@1224|Proteobacteria,1TIN6@1236|Gammaproteobacteria,1XZD3@135623|Vibrionales 135623|Vibrionales S Family of unknown function (DUF5363) - - - - - - - - - - - - DUF5363 k141_32739_5 1116375.VEJY3_12610 4.76e-138 394.0 COG0084@1|root,COG0084@2|Bacteria,1MW5C@1224|Proteobacteria,1RP5T@1236|Gammaproteobacteria,1XUGD@135623|Vibrionales 135623|Vibrionales L COG0084 Mg-dependent DNase yjjV - - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase k141_6763_1 218284.CCDN010000001_gene1310 7.01e-86 265.0 28N49@1|root,2ZB9S@2|Bacteria,1UY59@1239|Firmicutes,4HBU7@91061|Bacilli,1ZG1M@1386|Bacillus 91061|Bacilli S Spore germination B3/ GerAC like, C-terminal gerKC - - - - - - - - - - - Spore_GerAC k141_12825_1 42565.FP66_11750 4.07e-41 149.0 COG0739@1|root,COG3061@1|root,COG0739@2|Bacteria,COG3061@2|Bacteria,1MVTF@1224|Proteobacteria,1RM7S@1236|Gammaproteobacteria,1XIJI@135619|Oceanospirillales 135619|Oceanospirillales M Peptidase M23 - - - ko:K19304 - - - - ko00000,ko01000,ko01002,ko01011 - - - OapA,Peptidase_M23 k141_12825_2 42565.FP66_11755 2.17e-23 95.5 COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,1RNVM@1236|Gammaproteobacteria,1XIZ0@135619|Oceanospirillales 135619|Oceanospirillales S Belongs to the pirin family - - - ko:K06911 - - - - ko00000 - - - Pirin,Pirin_C k141_9187_1 502025.Hoch_1926 5.44e-15 77.4 COG0839@1|root,COG0839@2|Bacteria,1MWJV@1224|Proteobacteria,42RES@68525|delta/epsilon subdivisions,2WSB9@28221|Deltaproteobacteria,2YVT4@29|Myxococcales 28221|Deltaproteobacteria C Belongs to the complex I subunit 6 family nuoJ - 1.6.5.3 ko:K00339 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q3 k141_22162_1 1340434.AXVA01000003_gene1940 1.17e-155 445.0 COG0324@1|root,COG0324@2|Bacteria,1TPSC@1239|Firmicutes,4HAVW@91061|Bacilli,1ZBX9@1386|Bacillus 91061|Bacilli J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) miaA GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 - R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 - - - IPPT k141_22162_2 218284.CCDN010000001_gene1802 5.08e-45 145.0 COG1923@1|root,COG1923@2|Bacteria,1VEGI@1239|Firmicutes,4HKN1@91061|Bacilli,1ZQS1@1386|Bacillus 91061|Bacilli S RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs hfq - - ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 - - - ko00000,ko00001,ko03019,ko03036 - - - Hfq k141_6764_1 223926.28807732 9.27e-126 375.0 COG0369@1|root,COG0369@2|Bacteria,1QUAH@1224|Proteobacteria,1T1RJ@1236|Gammaproteobacteria,1XT6J@135623|Vibrionales 135623|Vibrionales P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component cysJ - 1.8.1.2 ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00176 R00858 RC00065 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_1,Flavodoxin_1,NAD_binding_1 k141_16187_1 1116375.VEJY3_19411 1.02e-155 441.0 COG0583@1|root,COG0583@2|Bacteria,1MX2A@1224|Proteobacteria,1RPHN@1236|Gammaproteobacteria,1Y264@135623|Vibrionales 135623|Vibrionales K COG0583 Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_20874_2 1232430.CAVG010000112_gene1009 3.95e-06 53.5 COG2755@1|root,COG2755@2|Bacteria,1VYJX@1239|Firmicutes,4HZCT@91061|Bacilli 91061|Bacilli E lipolytic protein G-D-S-L family - - - - - - - - - - - - - k141_3042_3 216591.BCAM1038 3.08e-51 169.0 2BU68@1|root,32PFD@2|Bacteria,1N2SX@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_17345_2 218284.CCDN010000001_gene85 4.9e-177 504.0 COG0771@1|root,COG0771@2|Bacteria,1TQ3P@1239|Firmicutes,4HA5P@91061|Bacilli,1ZARV@1386|Bacillus 91061|Bacilli M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) murD - 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase_C,Mur_ligase_M k141_27908_1 218284.CCDN010000005_gene3495 3.02e-229 645.0 COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,1TPKU@1239|Firmicutes,4H9KR@91061|Bacilli,1ZAVB@1386|Bacillus 91061|Bacilli GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type) fruA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563 2.7.1.202 ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1 - - PTS_EIIA_2,PTS_EIIC,PTS_IIB k141_32740_1 218284.CCDN010000010_gene4396 1.1e-28 107.0 COG3880@1|root,COG3880@2|Bacteria,1V6YM@1239|Firmicutes,4HH4R@91061|Bacilli,1ZG9T@1386|Bacillus 91061|Bacilli S protein with conserved CXXC pairs mcsA GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 - ko:K19411 - - - - ko00000 - - - UVR k141_30294_1 218284.CCDN010000005_gene3381 1.85e-10 58.2 COG0599@1|root,COG0599@2|Bacteria,1V8W7@1239|Firmicutes,4HHDQ@91061|Bacilli,1ZGYY@1386|Bacillus 91061|Bacilli S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity yurZ - - - - - - - - - - - CMD k141_14955_3 1279017.AQYJ01000028_gene2201 6.19e-37 134.0 COG3660@1|root,COG3660@2|Bacteria,1RC47@1224|Proteobacteria,1S53F@1236|Gammaproteobacteria,469PG@72275|Alteromonadaceae 1236|Gammaproteobacteria M Mitochondrial fission ELM1 - - - ko:K07276 - - - - ko00000 - - - Mito_fiss_Elm1 k141_23502_1 1385514.N782_18315 2.31e-71 233.0 COG0018@1|root,COG0018@2|Bacteria,1TPEZ@1239|Firmicutes,4HAR3@91061|Bacilli,2Y9IT@289201|Pontibacillus 91061|Bacilli J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA argS GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d k141_23502_2 218284.CCDN010000004_gene3059 1.62e-70 222.0 COG0772@1|root,COG0772@2|Bacteria,1TPGH@1239|Firmicutes,4HAV4@91061|Bacilli,1ZBSB@1386|Bacillus 91061|Bacilli D Belongs to the SEDS family rodA - - ko:K05837 - - - - ko00000,ko03036 - - - FTSW_RODA_SPOVE k141_22163_1 1479235.KK366039_gene2986 7.59e-177 500.0 COG0654@1|root,COG0654@2|Bacteria,1N8DE@1224|Proteobacteria,1S5UK@1236|Gammaproteobacteria 1236|Gammaproteobacteria CH lycopene cyclase crtY - 5.5.1.19 ko:K06443 ko00906,ko01100,ko01110,map00906,map01100,map01110 M00097 R03824,R04801,R05341,R06962,R07856 RC01004,RC01964 ko00000,ko00001,ko00002,ko01000 - - - Lycopene_cycl k141_37475_2 1279017.AQYJ01000028_gene2448 1.33e-98 294.0 COG0664@1|root,COG0664@2|Bacteria,1RE4X@1224|Proteobacteria,1S6Z7@1236|Gammaproteobacteria,46CPH@72275|Alteromonadaceae 1236|Gammaproteobacteria K Crp-like helix-turn-helix domain - - - ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 - - - ko00000,ko00001,ko03000 - - - HTH_Crp_2,cNMP_binding k141_37475_3 1042377.AFPJ01000024_gene753 5.55e-146 419.0 COG0385@1|root,COG0385@2|Bacteria,1MXF3@1224|Proteobacteria,1RNZF@1236|Gammaproteobacteria,466WA@72275|Alteromonadaceae 1236|Gammaproteobacteria S Bile acid sodium symporter - - - ko:K03453 - - - - ko00000 2.A.28 - - SBF k141_37475_4 1042377.AFPJ01000051_gene93 9.25e-87 270.0 COG3782@1|root,COG3782@2|Bacteria,1MZ3U@1224|Proteobacteria,1S9NQ@1236|Gammaproteobacteria,468I5@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF1853) - - - ko:K09977 - - - - ko00000 - - - DUF1853 k141_14089_2 1279017.AQYJ01000025_gene699 8.5e-233 652.0 COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,1RMB8@1236|Gammaproteobacteria,464AE@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria rmuC GO:0006139,GO:0006259,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360 - ko:K09760 - - - - ko00000 - - - RmuC k141_14089_3 1279017.AQYJ01000025_gene700 8.08e-126 367.0 COG0796@1|root,COG0796@2|Bacteria,1NAI2@1224|Proteobacteria,1RPU9@1236|Gammaproteobacteria,467NW@72275|Alteromonadaceae 1236|Gammaproteobacteria M Provides the (R)-glutamate required for cell wall biosynthesis murI GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0034645,GO:0036361,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 5.1.1.3 ko:K01776 ko00471,ko01100,map00471,map01100 - R00260 RC00302 ko00000,ko00001,ko01000,ko01011 - - iAPECO1_1312.APECO1_2496,iEC042_1314.EC042_4342,iECOK1_1307.ECOK1_4443,iECS88_1305.ECS88_4426,iPC815.YPO3909,iUMN146_1321.UM146_20110,iUTI89_1310.UTI89_C4562 Asp_Glu_race k141_14089_4 1279017.AQYJ01000025_gene701 5.56e-110 345.0 COG2887@1|root,COG2887@2|Bacteria,1QVX1@1224|Proteobacteria,1RP9I@1236|Gammaproteobacteria,465DQ@72275|Alteromonadaceae 1236|Gammaproteobacteria L PD-(D/E)XK nuclease superfamily lidB - - - - - - - - - - - PDDEXK_1 k141_31444_1 1157490.EL26_21465 8.05e-28 103.0 COG2204@1|root,COG2204@2|Bacteria,1UNHQ@1239|Firmicutes,4IUEM@91061|Bacilli 91061|Bacilli T cheY-homologous receiver domain - - - - - - - - - - - - Response_reg k141_31444_2 866895.HBHAL_3139 5.08e-37 128.0 COG2111@1|root,COG2111@2|Bacteria,1V3VF@1239|Firmicutes,4HHAN@91061|Bacilli,3NERX@45667|Halobacillus 91061|Bacilli P Domain related to MnhB subunit of Na+/H+ antiporter mrpB - - ko:K05566 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - MnhB k141_6766_1 218284.CCDN010000001_gene21 1.31e-172 491.0 COG0541@1|root,COG0541@2|Bacteria,1TP06@1239|Firmicutes,4H9T4@91061|Bacilli,1ZB4I@1386|Bacillus 91061|Bacilli U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY ffh - 3.6.5.4 ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko01000,ko02044 3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9 - - SRP54,SRP54_N,SRP_SPB k141_7832_1 1279017.AQYJ01000028_gene2137 4.74e-09 61.6 COG0308@1|root,COG0308@2|Bacteria,1PJTM@1224|Proteobacteria,1SYS3@1236|Gammaproteobacteria,4672R@72275|Alteromonadaceae 1236|Gammaproteobacteria E Peptidase family M1 domain - - 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - ERAP1_C,Peptidase_M1 k141_7832_2 1279017.AQYJ01000028_gene2137 1.16e-252 723.0 COG0308@1|root,COG0308@2|Bacteria,1PJTM@1224|Proteobacteria,1SYS3@1236|Gammaproteobacteria,4672R@72275|Alteromonadaceae 1236|Gammaproteobacteria E Peptidase family M1 domain - - 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - ERAP1_C,Peptidase_M1 k141_16188_1 218284.CCDN010000001_gene1552 1.51e-84 269.0 COG0768@1|root,COG0768@2|Bacteria,1TQHY@1239|Firmicutes,4HAFX@91061|Bacilli,1ZBJM@1386|Bacillus 91061|Bacilli M penicillin-binding protein pbpH - - ko:K21465 ko00550,map00550 - - - ko00000,ko00001,ko01011 - - - PBP_dimer,Transpeptidase k141_22164_2 1307436.PBF_00260 6.96e-117 340.0 COG0584@1|root,COG0584@2|Bacteria,1UGF1@1239|Firmicutes,4H9QE@91061|Bacilli,1ZPVG@1386|Bacillus 91061|Bacilli C Glycerophosphoryl diester phosphodiesterase family glpQ - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - DUF1080,GDPD k141_11862_1 491915.Aflv_0481 9.08e-33 117.0 2DDRJ@1|root,32U1X@2|Bacteria,1VCE7@1239|Firmicutes,4HKC5@91061|Bacilli,21X34@150247|Anoxybacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_21057_2 1042377.AFPJ01000043_gene955 2.62e-42 153.0 COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,1RQEX@1236|Gammaproteobacteria,463Z7@72275|Alteromonadaceae 1236|Gammaproteobacteria M Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane lptD GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0009279,GO:0009636,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0042221,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0050896,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:1901264 - ko:K04744 - - - - ko00000,ko02000 1.B.42.1 - iG2583_1286.G2583_0058 OstA,OstA_C k141_37699_1 1453501.JELR01000005_gene1567 1.77e-240 672.0 COG1012@1|root,COG1012@2|Bacteria,1MVGW@1224|Proteobacteria,1RN53@1236|Gammaproteobacteria,4656Y@72275|Alteromonadaceae 1236|Gammaproteobacteria C belongs to the aldehyde dehydrogenase family calB - 1.2.1.68 ko:K00154 - - - - ko00000,ko01000 - - - Aldedh k141_31601_1 218284.CCDN010000005_gene3428 1.04e-36 126.0 2CDZ2@1|root,32RYS@2|Bacteria,1VABM@1239|Firmicutes,4HKKB@91061|Bacilli,1ZHT7@1386|Bacillus 91061|Bacilli S Putative membrane protein yuiB - - - - - - - - - - - YuiB k141_31601_2 218284.CCDN010000005_gene3430 5.67e-16 75.9 COG3584@1|root,COG3584@2|Bacteria,1UYMN@1239|Firmicutes,4HIVQ@91061|Bacilli,1ZDD1@1386|Bacillus 91061|Bacilli S protein conserved in bacteria yuiC - - - - - - - - - - - 3D k141_3295_1 1168065.DOK_06295 7.7e-38 137.0 COG0664@1|root,COG0664@2|Bacteria,1MXID@1224|Proteobacteria,1SZB2@1236|Gammaproteobacteria,1JBZJ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria K helix_turn_helix, cAMP Regulatory protein - - - ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 - - - ko00000,ko00001,ko03000 - - - HTH_Crp_2,cNMP_binding k141_3295_2 493475.GARC_2758 1.29e-68 231.0 COG4774@1|root,COG4774@2|Bacteria,1NMCN@1224|Proteobacteria,1T3TQ@1236|Gammaproteobacteria,46AH5@72275|Alteromonadaceae 1236|Gammaproteobacteria P TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_24798_2 218284.CCDN010000001_gene386 1.32e-41 149.0 COG0778@1|root,COG0778@2|Bacteria,1UWU9@1239|Firmicutes,4H9ZQ@91061|Bacilli,1ZDAF@1386|Bacillus 91061|Bacilli C Nitroreductase family - - - - - - - - - - - - Nitroreductase k141_15155_1 218284.CCDN010000001_gene1742 8.42e-66 207.0 COG0491@1|root,COG0491@2|Bacteria,1TR4H@1239|Firmicutes,4HBXR@91061|Bacilli,1ZDVA@1386|Bacillus 91061|Bacilli S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B k141_4504_1 935836.JAEL01000006_gene2840 3.01e-44 144.0 COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,4HNJC@91061|Bacilli,1ZHTU@1386|Bacillus 91061|Bacilli K Cold-shock protein cspD - - ko:K03704 - - - - ko00000,ko03000 - - - CSD k141_35587_1 1294265.JCM21738_194 4.41e-210 599.0 COG3256@1|root,COG3256@2|Bacteria,1TSW2@1239|Firmicutes,4HCFR@91061|Bacilli,1ZDGS@1386|Bacillus 91061|Bacilli P Cytochrome C and Quinol oxidase polypeptide I - - 1.7.2.5 ko:K04561 ko00910,ko01120,map00910,map01120 M00529 R00294 RC02794 ko00000,ko00001,ko00002,ko01000 3.D.4.10 - - COX1 k141_22537_1 1453501.JELR01000001_gene2961 5.83e-280 775.0 COG0204@1|root,COG3176@1|root,COG0204@2|Bacteria,COG3176@2|Bacteria,1MWIM@1224|Proteobacteria,1RQD4@1236|Gammaproteobacteria,464MD@72275|Alteromonadaceae 1236|Gammaproteobacteria I Acyltransferase - - - - - - - - - - - - Acetyltransf_5,Acyltransferase k141_9501_1 1294265.JCM21738_4414 1.79e-189 531.0 COG0006@1|root,COG0006@2|Bacteria,1TQ6R@1239|Firmicutes,4HA5I@91061|Bacilli,1ZBZE@1386|Bacillus 91061|Bacilli E COG0006 Xaa-Pro aminopeptidase pepQ - 3.4.13.9 ko:K01271 - - - - ko00000,ko01000,ko01002 - - - Creatinase_N,Peptidase_M24 k141_5861_1 1340434.AXVA01000003_gene1640 3.51e-28 102.0 2EKIW@1|root,33E8T@2|Bacteria,1VKHP@1239|Firmicutes,4HRCK@91061|Bacilli,1ZJ3S@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_5861_2 218284.CCDN010000001_gene198 2.16e-121 356.0 COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,4HA13@91061|Bacilli,1ZAWQ@1386|Bacillus 91061|Bacilli E Aminotransferase patA - - ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 M00525 R04467 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k141_10508_1 1453501.JELR01000002_gene59 4.35e-207 590.0 COG0365@1|root,COG0365@2|Bacteria,1MUX7@1224|Proteobacteria,1RPGT@1236|Gammaproteobacteria,465WE@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases acsA - 6.2.1.16 ko:K01907 ko00280,ko00650,map00280,map00650 - R01357 RC00004,RC00014 ko00000,ko00001,ko01000,ko01004 - - - ACAS_N,AMP-binding,AMP-binding_C k141_10508_2 1279017.AQYJ01000026_gene391 1.06e-144 415.0 COG0583@1|root,COG0583@2|Bacteria,1MUWX@1224|Proteobacteria,1RMVV@1236|Gammaproteobacteria,466MX@72275|Alteromonadaceae 1236|Gammaproteobacteria K Transcriptional regulator - - - ko:K17737 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate k141_10508_3 1279017.AQYJ01000026_gene392 1.2e-85 254.0 COG0783@1|root,COG0783@2|Bacteria,1RAC5@1224|Proteobacteria,1S2H7@1236|Gammaproteobacteria,466DT@72275|Alteromonadaceae 1236|Gammaproteobacteria P Belongs to the Dps family dps - - ko:K04047 - - - - ko00000,ko03036 - - - Ferritin k141_10508_4 1042377.AFPJ01000021_gene2141 3.47e-29 108.0 COG3245@1|root,COG3245@2|Bacteria,1MZBZ@1224|Proteobacteria,1S9Z9@1236|Gammaproteobacteria 1236|Gammaproteobacteria C cytochrome c5 cyc - 1.9.3.1 ko:K02277 ko00190,ko01100,map00190,map01100 M00155 - - ko00000,ko00001,ko00002,ko01000 3.D.4.4 - - Cytochrome_CBB3 k141_10508_5 1453501.JELR01000001_gene2918 1.78e-238 664.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,469RZ@72275|Alteromonadaceae 1236|Gammaproteobacteria C Aldehyde dehydrogenase family - - 1.2.1.3,1.2.1.71,1.2.1.9 ko:K00128,ko:K00131,ko:K06447 ko00010,ko00030,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130,map01200 M00135,M00308,M00633 R00264,R00631,R00710,R00904,R01058,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05049,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_31602_1 218284.CCDN010000007_gene3952 3.87e-125 363.0 COG4294@1|root,COG4294@2|Bacteria,1TTCB@1239|Firmicutes,4H9PY@91061|Bacilli,1ZCJ7@1386|Bacillus 91061|Bacilli L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion uvsE - - ko:K13281 - - - - ko00000,ko01000 - - - UvdE k141_22538_1 1196323.ALKF01000155_gene5374 1.31e-49 167.0 COG1349@1|root,COG1349@2|Bacteria,1U2B1@1239|Firmicutes,4IQMQ@91061|Bacilli,276FI@186822|Paenibacillaceae 91061|Bacilli K DeoR C terminal sensor domain - - - - - - - - - - - - DeoRC,HTH_DeoR k141_22538_2 1340434.AXVA01000008_gene3656 1.93e-19 86.3 COG1387@1|root,COG1387@2|Bacteria,1UZ0M@1239|Firmicutes,4HAUH@91061|Bacilli,1ZE5C@1386|Bacillus 91061|Bacilli E COG1387 Histidinol phosphatase and related hydrolases of the PHP family hisJ - 3.1.3.15 ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R03013 RC00017 ko00000,ko00001,ko00002,ko01000 - - - PHP k141_4505_1 439375.Oant_2723 1.49e-67 213.0 COG3293@1|root,COG3293@2|Bacteria,1PVIT@1224|Proteobacteria,2TURP@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Transposase - - - - - - - - - - - - DDE_Tnp_1,DUF4096 k141_9502_1 345219.Bcoa_2723 3.46e-43 145.0 COG0239@1|root,COG0239@2|Bacteria,1VEH7@1239|Firmicutes,4HNI0@91061|Bacilli,1ZJ3M@1386|Bacillus 91061|Bacilli D Important for reducing fluoride concentration in the cell, thus reducing its toxicity crcB GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - ko:K06199 - - - - ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 - - CRCB k141_9502_2 1340434.AXVA01000016_gene698 1.88e-29 108.0 COG0239@1|root,COG0239@2|Bacteria,1VM30@1239|Firmicutes,4HRC4@91061|Bacilli,1ZIV0@1386|Bacillus 91061|Bacilli D Important for reducing fluoride concentration in the cell, thus reducing its toxicity crcB GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - ko:K06199 - - - - ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 - - CRCB k141_11866_1 1123228.AUIH01000008_gene2414 1.54e-163 467.0 COG2224@1|root,COG2224@2|Bacteria,1MWIF@1224|Proteobacteria,1RQAK@1236|Gammaproteobacteria,1XI4D@135619|Oceanospirillales 135619|Oceanospirillales C Phosphoenolpyruvate phosphomutase - - 4.1.3.1 ko:K01637 ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200 M00012 R00479 RC00311,RC00313 ko00000,ko00001,ko00002,ko01000 - - - ICL k141_17513_1 218284.CCDN010000001_gene1105 2.86e-133 390.0 COG0699@1|root,COG0699@2|Bacteria,1TPPG@1239|Firmicutes,4HBH1@91061|Bacilli,1ZBNH@1386|Bacillus 91061|Bacilli S ATPase. Has a role at an early stage in the morphogenesis of the spore coat spoIVA GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009653,GO:0009847,GO:0009987,GO:0010927,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022607,GO:0030154,GO:0030203,GO:0030312,GO:0030435,GO:0030554,GO:0031160,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0032989,GO:0034622,GO:0035639,GO:0036094,GO:0042244,GO:0042546,GO:0042601,GO:0042763,GO:0043167,GO:0043168,GO:0043170,GO:0043591,GO:0043595,GO:0043933,GO:0043934,GO:0044085,GO:0044426,GO:0044462,GO:0044464,GO:0045229,GO:0048646,GO:0048856,GO:0048869,GO:0051258,GO:0051259,GO:0065003,GO:0070499,GO:0070590,GO:0070726,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 - ko:K06398 - - - - ko00000 - - - Spore_IV_A k141_33012_1 1279017.AQYJ01000018_gene776 5.21e-23 96.3 COG3588@1|root,COG3588@2|Bacteria,1MVFK@1224|Proteobacteria,1RQ57@1236|Gammaproteobacteria,469X9@72275|Alteromonadaceae 1236|Gammaproteobacteria G Fructose-bisphosphate aldolase class-I alf1 - 4.1.2.13 ko:K01623 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000,ko03036,ko04131,ko04147 - - - Glycolytic k141_33012_2 1279017.AQYJ01000018_gene775 4.21e-65 206.0 COG2267@1|root,COG2267@2|Bacteria,1MWF5@1224|Proteobacteria,1RNQR@1236|Gammaproteobacteria,46CDV@72275|Alteromonadaceae 1236|Gammaproteobacteria I Serine aminopeptidase, S33 ynbC GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0008150,GO:0008152,GO:0016020,GO:0016298,GO:0016787,GO:0016788,GO:0044238,GO:0071704 - - - - - - - - - - Hydrolase_4,Methyltransf_20 k141_1135_1 1294265.JCM21738_2394 4.51e-75 233.0 2BZRV@1|root,2Z8AV@2|Bacteria,1UX40@1239|Firmicutes,4HAVP@91061|Bacilli,1ZDM4@1386|Bacillus 91061|Bacilli S Nuclease-related domain - - - - - - - - - - - - NERD k141_35589_1 218284.CCDN010000001_gene1684 5.86e-166 469.0 COG1309@1|root,COG1309@2|Bacteria,1UDHR@1239|Firmicutes,4HFAX@91061|Bacilli 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - TetR_N k141_4506_1 1453501.JELR01000001_gene1868 4.84e-90 275.0 COG0707@1|root,COG0707@2|Bacteria,1MWQP@1224|Proteobacteria,1T31H@1236|Gammaproteobacteria,46D2Z@72275|Alteromonadaceae 1236|Gammaproteobacteria M Glycosyl transferase family 1 - - - - - - - - - - - - Glyco_trans_1_3 k141_34285_1 42565.FP66_07695 1.46e-193 536.0 COG0639@1|root,COG0639@2|Bacteria,1MV10@1224|Proteobacteria,1RPUJ@1236|Gammaproteobacteria,1XH8Y@135619|Oceanospirillales 135619|Oceanospirillales T Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP apaH - 3.6.1.41 ko:K01525 ko00230,map00230 - R00125 RC00002 ko00000,ko00001,ko01000 - - - Metallophos k141_34285_2 42565.FP66_07700 7.27e-54 170.0 COG2967@1|root,COG2967@2|Bacteria,1MZ2Z@1224|Proteobacteria,1S8SE@1236|Gammaproteobacteria,1XKBU@135619|Oceanospirillales 135619|Oceanospirillales P ApaG domain apaG - - ko:K06195 - - - - ko00000 - - - DUF525 k141_26130_1 223926.28806129 6.61e-114 328.0 COG0118@1|root,COG0118@2|Bacteria,1MU4X@1224|Proteobacteria,1RRP3@1236|Gammaproteobacteria,1XUI3@135623|Vibrionales 135623|Vibrionales E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR hisH GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - - GATase k141_24801_1 1294265.JCM21738_1823 3.22e-129 375.0 COG1960@1|root,COG1960@2|Bacteria,1TSN3@1239|Firmicutes,4HB0T@91061|Bacilli,1ZDR4@1386|Bacillus 91061|Bacilli I Acyl-CoA dehydrogenase, N-terminal domain - - 1.3.8.7 ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_24802_2 171693.BN988_02229 1.6e-25 102.0 COG1063@1|root,COG1063@2|Bacteria,1VRPE@1239|Firmicutes,4HU28@91061|Bacilli 91061|Bacilli E alcohol dehydrogenase - - 1.1.1.1 ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N k141_11867_1 218284.CCDN010000007_gene3912 4.54e-83 253.0 COG0561@1|root,COG0561@2|Bacteria,1V5FB@1239|Firmicutes,4HGY8@91061|Bacilli,1ZDBI@1386|Bacillus 91061|Bacilli S hydrolases of the HAD superfamily ycsE - - - - - - - - - - - Hydrolase_3 k141_11867_2 1385514.N782_12255 2.9e-30 119.0 COG2133@1|root,COG2133@2|Bacteria,1TR38@1239|Firmicutes,4HBME@91061|Bacilli,2Y9W8@289201|Pontibacillus 91061|Bacilli G Quinoprotein glucose dehydrogenase - - - - - - - - - - - - GSDH,fn3 k141_33013_1 218284.CCDN010000002_gene2187 6.12e-95 279.0 COG1225@1|root,COG1225@2|Bacteria,1V4YG@1239|Firmicutes,4HHP6@91061|Bacilli,1ZEZC@1386|Bacillus 91061|Bacilli O Redoxin - - - - - - - - - - - - AhpC-TSA k141_33013_2 218284.CCDN010000002_gene2185 0.000109 43.5 COG2130@1|root,COG2130@2|Bacteria,1TQUE@1239|Firmicutes,4HCHY@91061|Bacilli,1ZC4N@1386|Bacillus 91061|Bacilli S N-terminal domain of oxidoreductase yfmJ - - ko:K07119 - - - - ko00000 - - - ADH_N_2,ADH_zinc_N k141_3296_1 218284.CCDN010000008_gene4137 1.88e-307 855.0 COG0058@1|root,COG0058@2|Bacteria,1TQAJ@1239|Firmicutes,4H9XI@91061|Bacilli,1ZCRF@1386|Bacillus 91061|Bacilli G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties glgP GO:0000272,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005976,GO:0005977,GO:0005980,GO:0006073,GO:0006091,GO:0006112,GO:0008144,GO:0008150,GO:0008152,GO:0008184,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0015980,GO:0016052,GO:0016740,GO:0016757,GO:0016758,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901575 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 - R02111 - ko00000,ko00001,ko01000 - GT35 iYO844.BSU30940 Phosphorylase k141_17516_1 218284.CCDN010000005_gene3162 7.2e-81 246.0 COG1024@1|root,COG1024@2|Bacteria,1TRCQ@1239|Firmicutes,4HDUU@91061|Bacilli,1ZARB@1386|Bacillus 91061|Bacilli I enoyl-CoA hydratase yhaR - - - - - - - - - - - ECH_1 k141_4508_1 1122194.AUHU01000003_gene2327 3.96e-71 239.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MV8W@1224|Proteobacteria,1RMQA@1236|Gammaproteobacteria,46619@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec k141_33023_1 223926.28808251 1.34e-32 117.0 2AWR4@1|root,31NN2@2|Bacteria,1QKCN@1224|Proteobacteria,1TIG5@1236|Gammaproteobacteria,1XZ2P@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_33023_2 223926.28808252 1.6e-30 109.0 2991E@1|root,2ZW4Z@2|Bacteria,1PB6X@1224|Proteobacteria,1SW7E@1236|Gammaproteobacteria,1XZ03@135623|Vibrionales 135623|Vibrionales - - VPA0114 - - - - - - - - - - - - k141_33023_3 223926.28808261 1.84e-83 249.0 COG1011@1|root,COG1011@2|Bacteria,1RI67@1224|Proteobacteria,1S6KI@1236|Gammaproteobacteria,1XXRK@135623|Vibrionales 135623|Vibrionales S HAD-hyrolase-like - - - ko:K07025 - - - - ko00000 - - - HAD_2 k141_33023_4 1116375.VEJY3_16161 1.95e-86 259.0 COG1670@1|root,COG1670@2|Bacteria,1RC7M@1224|Proteobacteria,1S20T@1236|Gammaproteobacteria,1XY20@135623|Vibrionales 135623|Vibrionales J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins - - - - - - - - - - - - Acetyltransf_3 k141_33023_5 223926.28808265 5.69e-241 664.0 COG3005@1|root,COG3005@2|Bacteria,1MWV2@1224|Proteobacteria,1RQ52@1236|Gammaproteobacteria,1XSGP@135623|Vibrionales 135623|Vibrionales C Belongs to the TorC TorY family torY - - ko:K07821 - - - - ko00000,ko02000 5.A.3.4 - - Cytochrom_NNT k141_33023_6 1219076.N646_3561 0.0 1618.0 COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,1RMVE@1236|Gammaproteobacteria,1XV0F@135623|Vibrionales 135623|Vibrionales C COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing torZ - 1.7.2.3 ko:K07811,ko:K07812 ko02020,map02020 - - - ko00000,ko00001,ko01000,ko02000 5.A.3.4 - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal k141_33023_7 1116375.VEJY3_16191 3.72e-123 353.0 COG0819@1|root,COG0819@2|Bacteria,1R21S@1224|Proteobacteria,1RQY6@1236|Gammaproteobacteria,1XUAI@135623|Vibrionales 135623|Vibrionales K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway - - 3.5.99.2 ko:K03707 ko00730,ko01100,map00730,map01100 - R02133,R09993 RC00224,RC00652,RC02832 ko00000,ko00001,ko01000,ko03000 - - - TENA_THI-4 k141_33023_8 1219076.N646_3566 4.72e-214 592.0 COG0715@1|root,COG0715@2|Bacteria,1MVRA@1224|Proteobacteria,1RNG0@1236|Gammaproteobacteria,1XUZM@135623|Vibrionales 135623|Vibrionales P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components - - - ko:K15598 ko02010,map02010 M00442 - - ko00000,ko00001,ko00002,ko02000 3.A.1.17.3,3.A.1.17.6 - - NMT1 k141_33023_9 1280001.BAOA01000014_gene958 1.7e-18 82.0 COG0600@1|root,COG0600@2|Bacteria,1N0FV@1224|Proteobacteria,1RPE6@1236|Gammaproteobacteria,1XSYY@135623|Vibrionales 135623|Vibrionales P Binding-protein-dependent transport system inner membrane component - - - ko:K15599 ko02010,map02010 M00442 - - ko00000,ko00001,ko00002,ko02000 3.A.1.17.3,3.A.1.17.6 - - BPD_transp_1 k141_33023_10 1116375.VEJY3_16201 3.94e-109 319.0 COG0600@1|root,COG0600@2|Bacteria,1N0FV@1224|Proteobacteria,1RPE6@1236|Gammaproteobacteria,1XSYY@135623|Vibrionales 135623|Vibrionales P Binding-protein-dependent transport system inner membrane component - - - ko:K15599 ko02010,map02010 M00442 - - ko00000,ko00001,ko00002,ko02000 3.A.1.17.3,3.A.1.17.6 - - BPD_transp_1 k141_33023_11 1116375.VEJY3_16206 7.19e-145 412.0 COG1116@1|root,COG1116@2|Bacteria,1RASI@1224|Proteobacteria,1RY7H@1236|Gammaproteobacteria,1XU0G@135623|Vibrionales 135623|Vibrionales P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component - - - ko:K15600 ko02010,map02010 M00442 - - ko00000,ko00001,ko00002,ko02000 3.A.1.17.3,3.A.1.17.6 - - ABC_tran k141_33023_12 674977.VMC_05140 4.37e-168 474.0 COG0351@1|root,COG0351@2|Bacteria,1MU9J@1224|Proteobacteria,1RNFP@1236|Gammaproteobacteria,1XSEN@135623|Vibrionales 135623|Vibrionales H Phosphomethylpyrimidine kinase thiD - 2.7.1.49,2.7.4.7 ko:K00941 ko00730,ko01100,map00730,map01100 M00127 R03471,R04509 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Phos_pyr_kin k141_20135_1 42565.FP66_06675 4.65e-71 230.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XNI7@135619|Oceanospirillales 135619|Oceanospirillales T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - - - - - - - - - - EAL,GGDEF,PAS_9 k141_5903_1 218284.CCDN010000002_gene2041 1.52e-45 168.0 COG1277@1|root,COG1277@2|Bacteria,1TRJ8@1239|Firmicutes,4HA9I@91061|Bacilli,1ZCXM@1386|Bacillus 91061|Bacilli S ABC-type transport system involved in multi-copper enzyme maturation permease component - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - - k141_16456_1 574375.BAGA_06545 1.54e-81 275.0 COG1404@1|root,COG1404@2|Bacteria,1TPH1@1239|Firmicutes,4HBQH@91061|Bacilli,1ZBS0@1386|Bacillus 91061|Bacilli O Belongs to the peptidase S8 family prtS - 3.4.21.110,3.4.21.96 ko:K01361,ko:K08652 - - - - ko00000,ko01000,ko01002,ko03110 - - - FIVAR,Gram_pos_anchor,Inhibitor_I9,PA,Peptidase_S8,SLH,YSIRK_signal,fn3_5 k141_24834_1 501479.ACNW01000097_gene1064 3.62e-28 105.0 2CJ7A@1|root,32S9D@2|Bacteria,1N1NT@1224|Proteobacteria,2UCA0@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_24834_2 388399.SSE37_16158 1.27e-41 143.0 28INX@1|root,2Z8P0@2|Bacteria,1MWCP@1224|Proteobacteria,2U0Y7@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_17547_2 596153.Alide_2691 4.27e-123 374.0 COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2VIEX@28216|Betaproteobacteria,4AAEG@80864|Comamonadaceae 28216|Betaproteobacteria EH Belongs to the TPP enzyme family ilvG5 - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N k141_21087_1 1117318.PRUB_16332 1.18e-83 283.0 COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,1RPAG@1236|Gammaproteobacteria,2Q3X9@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria Q COG1020 Non-ribosomal peptide synthetase modules and related proteins - - - - - - - - - - - - ABC_tran,AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase k141_2069_1 665952.HMPREF1015_01697 8.4e-87 276.0 COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,1TPKU@1239|Firmicutes,4H9KR@91061|Bacilli,1ZAVB@1386|Bacillus 91061|Bacilli GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type) fruA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563 2.7.1.202 ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1 - - PTS_EIIA_2,PTS_EIIC,PTS_IIB k141_22577_1 745411.B3C1_04060 2.67e-72 238.0 COG3227@1|root,COG4935@1|root,COG3227@2|Bacteria,COG4935@2|Bacteria,1P416@1224|Proteobacteria,1RR7I@1236|Gammaproteobacteria,1J72E@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Thermolysin metallopeptidase, catalytic domain - - 3.4.24.25,3.4.24.26 ko:K01399,ko:K08604 ko01503,ko02024,ko05110,ko05111,map01503,map02024,map05110,map05111 - - - ko00000,ko00001,ko01000,ko01002 - - - FTP,PKD,PPC,P_proprotein,PepSY,Peptidase_M4,Peptidase_M4_C k141_1155_2 42565.FP66_09230 2.05e-165 471.0 COG2718@1|root,COG2718@2|Bacteria,1MWQM@1224|Proteobacteria,1RQWC@1236|Gammaproteobacteria,1XHCJ@135619|Oceanospirillales 135619|Oceanospirillales S Belongs to the UPF0229 family - - - ko:K09786 - - - - ko00000 - - - DUF444 k141_17548_2 512565.AMIS_55930 1.8e-47 160.0 COG0412@1|root,COG0412@2|Bacteria,2I37P@201174|Actinobacteria,4DCSE@85008|Micromonosporales 201174|Actinobacteria Q dienelactone hydrolase - - - - - - - - - - - - DLH k141_5905_1 218284.CCDN010000007_gene3819 1.64e-77 239.0 COG1226@1|root,COG1226@2|Bacteria,1TT0B@1239|Firmicutes,4HBDX@91061|Bacilli,1ZDQI@1386|Bacillus 91061|Bacilli P Ion channel kch - - ko:K10716 - - - - ko00000,ko02000 1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6 - - Ion_trans_2,TrkA_N k141_15161_1 935836.JAEL01000007_gene2897 1.68e-19 87.8 COG1620@1|root,COG1620@2|Bacteria,1TQNM@1239|Firmicutes,4HAF3@91061|Bacilli,1ZC0U@1386|Bacillus 91061|Bacilli C L-lactate permease - - - ko:K03303 - - - - ko00000,ko02000 2.A.14 - - Lactate_perm k141_28141_1 1453501.JELR01000001_gene1942 2.27e-65 202.0 COG2825@1|root,COG2825@2|Bacteria,1MZVJ@1224|Proteobacteria,1SA69@1236|Gammaproteobacteria,468H2@72275|Alteromonadaceae 1236|Gammaproteobacteria M Outer membrane protein (OmpH-like) ompH - - ko:K06142 - - - - ko00000 - - - OmpH k141_2070_1 1307436.PBF_00690 3.65e-26 107.0 COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,4H9RZ@91061|Bacilli,1ZBEA@1386|Bacillus 91061|Bacilli NT chemotaxis protein tlpC - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal,sCache_3_3 k141_34302_1 218284.CCDN010000001_gene920 3.78e-22 100.0 COG5412@1|root,COG5412@2|Bacteria,1TQ28@1239|Firmicutes,4HCMX@91061|Bacilli,1ZEVU@1386|Bacillus 91061|Bacilli D Phage tail tape measure protein, TP901 family - - - - - - - - - - - - PhageMin_Tail k141_34302_2 218284.CCDN010000001_gene921 3.64e-144 429.0 COG4722@1|root,COG4722@2|Bacteria,1UHNJ@1239|Firmicutes,4HF24@91061|Bacilli 91061|Bacilli S Phage tail protein - - - - - - - - - - - - Sipho_tail k141_34302_3 218284.CCDN010000001_gene922 2.15e-86 287.0 COG0419@1|root,COG4733@1|root,COG0419@2|Bacteria,COG4733@2|Bacteria,1TQWP@1239|Firmicutes,4HEU7@91061|Bacilli,1ZF79@1386|Bacillus 91061|Bacilli L Phage minor structural protein - - - - - - - - - - - - Prophage_tail k141_24836_1 218284.CCDN010000001_gene747 1.29e-62 204.0 COG0561@1|root,COG0561@2|Bacteria,1TR3N@1239|Firmicutes,4HC8P@91061|Bacilli,1ZBP7@1386|Bacillus 91061|Bacilli S Stage IV sporulation yqfD - - ko:K06438 - - - - ko00000 - - - YqfD k141_5906_2 218284.CCDN010000006_gene3505 9.94e-32 112.0 COG0526@1|root,COG0526@2|Bacteria,1VEVR@1239|Firmicutes,4HNM9@91061|Bacilli,1ZIVX@1386|Bacillus 91061|Bacilli CO Thioredoxin yusE GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - - - - - - - - - - Thioredoxin k141_29542_1 218284.CCDN010000005_gene3343 4.19e-135 393.0 COG3104@1|root,COG3104@2|Bacteria,1TP81@1239|Firmicutes,4HAF2@91061|Bacilli,1ZAVZ@1386|Bacillus 91061|Bacilli E amino acid peptide transporter - - - ko:K03305 - - - - ko00000 2.A.17 - - PTR2 k141_17549_1 1453501.JELR01000002_gene1215 2.1e-57 198.0 COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,1RMU8@1236|Gammaproteobacteria,46404@72275|Alteromonadaceae 1236|Gammaproteobacteria G Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II algC GO:0003674,GO:0003824,GO:0004615,GO:0005975,GO:0008150,GO:0008152,GO:0016853,GO:0016866,GO:0016868,GO:0044238,GO:0071704 5.4.2.2,5.4.2.8 ko:K01840,ko:K15778 ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00114 R00959,R01057,R01818,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV k141_17549_2 1423747.BAMJ01000002_gene203 2.58e-06 50.4 COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,4HAK8@91061|Bacilli,3F3XX@33958|Lactobacillaceae 91061|Bacilli H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine coaBC - 4.1.1.36,6.3.2.5 ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 - - - DFP,Flavoprotein k141_20138_2 1294265.JCM21738_131 6.13e-48 155.0 COG0723@1|root,COG0723@2|Bacteria,1TQUH@1239|Firmicutes,4HBX1@91061|Bacilli,1ZFNX@1386|Bacillus 91061|Bacilli C Menaquinol-cytochrome c reductase qcrA - - ko:K03886 ko00190,ko01100,map00190,map01100 M00151 - - ko00000,ko00001,ko00002,ko01000 - - - CytB6-F_Fe-S,Rieske k141_22578_1 218284.CCDN010000002_gene2171 6.7e-59 187.0 COG4758@1|root,COG4758@2|Bacteria,1V3D0@1239|Firmicutes,4HDIA@91061|Bacilli,1ZDPB@1386|Bacillus 91061|Bacilli S Cell wall-active antibiotics response 4TMS YvqF yvqF - - ko:K11622 ko02020,map02020 - - - ko00000,ko00001 - - - DUF2154 k141_36439_1 1280001.BAOA01000047_gene1799 3.19e-46 164.0 COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,1RPAG@1236|Gammaproteobacteria,1XSKY@135623|Vibrionales 135623|Vibrionales Q COG1020 Non-ribosomal peptide synthetase modules and related proteins - - 6.3.2.14 ko:K02364 ko01053,ko01110,ko01130,map01053,map01110,map01130 - R07644 RC00162,RC03046 ko00000,ko00001,ko01000,ko01008 - - - AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase k141_27354_1 1453501.JELR01000002_gene346 4.92e-76 234.0 COG0811@1|root,COG0811@2|Bacteria,1PKF8@1224|Proteobacteria,1RRWP@1236|Gammaproteobacteria,465RQ@72275|Alteromonadaceae 1236|Gammaproteobacteria U COG0811 Biopolymer transport proteins - - - - - - - - - - - - MotA_ExbB k141_33297_1 1042377.AFPJ01000010_gene1457 4.06e-142 414.0 COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,1RQ8B@1236|Gammaproteobacteria,465GI@72275|Alteromonadaceae 1236|Gammaproteobacteria T His Kinase A (phosphoacceptor) domain styS - - - - - - - - - - - HATPase_c,PAS_8 k141_28543_1 1042377.AFPJ01000023_gene657 6.41e-09 62.8 COG1361@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4932@2|Bacteria,1QUEG@1224|Proteobacteria 1224|Proteobacteria M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - - - - - - - - - - SdrD_B k141_8338_1 218284.CCDN010000001_gene685 1.77e-221 630.0 COG0507@1|root,COG0507@2|Bacteria,1TPZH@1239|Firmicutes,4HATQ@91061|Bacilli,1ZAYS@1386|Bacillus 91061|Bacilli L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity recD2 - 3.1.11.5 ko:K03581 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_30,HHH_4,HHH_5,UvrD_C_2 k141_19029_1 1294265.JCM21738_1719 8.52e-22 85.5 COG4895@1|root,COG4895@2|Bacteria,1VEG3@1239|Firmicutes,4HNJA@91061|Bacilli,1ZIX5@1386|Bacillus 91061|Bacilli S Uncharacterized conserved protein (DUF2196) ywbE - - - - - - - - - - - DUF2196 k141_19029_2 1294265.JCM21738_1720 1.37e-31 117.0 29RX3@1|root,30D18@2|Bacteria,1UAPA@1239|Firmicutes,4IM1X@91061|Bacilli,1ZIS4@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_26165_2 218284.CCDN010000005_gene3269 7e-161 452.0 COG2267@1|root,COG2267@2|Bacteria,1UZM1@1239|Firmicutes,4HFJW@91061|Bacilli,1ZD5F@1386|Bacillus 91061|Bacilli I carboxylic ester hydrolase activity yjaU - - - - - - - - - - - Hydrolase_4 k141_2386_1 1294265.JCM21738_287 1.76e-116 337.0 COG4974@1|root,COG4974@2|Bacteria,1TPQB@1239|Firmicutes,4HARA@91061|Bacilli,1ZB91@1386|Bacillus 91061|Bacilli L tyrosine recombinase XerC xerC - - ko:K03733,ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase k141_20218_1 190486.XAC4126 2.29e-34 121.0 COG4104@1|root,COG4104@2|Bacteria,1N0ZK@1224|Proteobacteria,1S9FK@1236|Gammaproteobacteria,1X7GV@135614|Xanthomonadales 135614|Xanthomonadales S PAAR motif - - - - - - - - - - - - PAAR_motif k141_20218_2 1279017.AQYJ01000027_gene1536 1.57e-29 110.0 COG1716@1|root,COG1716@2|Bacteria,1REN8@1224|Proteobacteria,1S4U3@1236|Gammaproteobacteria 1236|Gammaproteobacteria T ATPase activity - - - - - - - - - - - - - k141_23793_1 218284.CCDN010000010_gene4386 6.12e-256 707.0 COG0215@1|root,COG0215@2|Bacteria,1TP9D@1239|Firmicutes,4HA6D@91061|Bacilli,1ZB69@1386|Bacillus 91061|Bacilli J Belongs to the class-I aminoacyl-tRNA synthetase family cysS GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 6.1.1.16 ko:K01883 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_2,tRNA-synt_1e,tRNA-synt_1g k141_32109_1 218284.CCDN010000002_gene2256 1.81e-104 311.0 COG0477@1|root,COG0477@2|Bacteria,1UIJV@1239|Firmicutes,4ISKN@91061|Bacilli,1ZS6S@1386|Bacillus 91061|Bacilli EGP COG0477 Permeases of the major facilitator superfamily yfkF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - MFS_1,MFS_1_like k141_26166_1 1196029.ALIM01000034_gene1866 1.45e-58 187.0 COG3142@1|root,COG3142@2|Bacteria,1UYI8@1239|Firmicutes,4IR0G@91061|Bacilli,1ZHIS@1386|Bacillus 91061|Bacilli P Participates in the control of copper homeostasis cutC - - ko:K06201 - - - - ko00000 - - - CutC k141_28579_1 1294265.JCM21738_2563 1.35e-107 317.0 COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,4H9YB@91061|Bacilli,1ZBA4@1386|Bacillus 91061|Bacilli E Belongs to the ABC transporter superfamily appF - - ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY k141_4798_1 218284.CCDN010000008_gene4166 1.23e-57 182.0 COG1268@1|root,COG1268@2|Bacteria,1VAY6@1239|Firmicutes,4HHJM@91061|Bacilli,1ZEP6@1386|Bacillus 91061|Bacilli S BioY family bioY2 - - ko:K03523 ko02010,map02010 M00581,M00582 - - ko00000,ko00001,ko00002,ko02000 2.A.88.1,2.A.88.2 - - BioY k141_4798_2 218284.CCDN010000002_gene2379 3.19e-73 225.0 2DZYA@1|root,32VN2@2|Bacteria,1VA7J@1239|Firmicutes,4HKH0@91061|Bacilli,1ZF7X@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_17866_1 218284.CCDN010000002_gene2865 1e-18 82.0 29N94@1|root,3096Z@2|Bacteria,1V49G@1239|Firmicutes,4HHC5@91061|Bacilli,1ZH7E@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_17866_2 218284.CCDN010000002_gene2864 7.64e-104 311.0 COG1396@1|root,COG1396@2|Bacteria,1VDMN@1239|Firmicutes,4HDVP@91061|Bacilli,1ZS6Z@1386|Bacillus 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - ko:K20480 ko02024,map02024 - - - ko00000,ko00001,ko03000 - - - HTH_3 k141_5984_1 1453501.JELR01000005_gene1583 4.42e-129 390.0 COG1472@1|root,COG1472@2|Bacteria,1MVIV@1224|Proteobacteria,1RMA0@1236|Gammaproteobacteria,465BV@72275|Alteromonadaceae 1236|Gammaproteobacteria G Family 3 - - 3.2.1.21 ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 - R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - GH3 - Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C k141_3611_1 223926.28807722 3.15e-116 358.0 COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,1RMS9@1236|Gammaproteobacteria,1XSPJ@135623|Vibrionales 135623|Vibrionales L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate uvrA GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009380,GO:0009381,GO:0009987,GO:0016787,GO:0016788,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran k141_17867_1 203122.Sde_0790 1.04e-140 418.0 COG3589@1|root,COG3589@2|Bacteria,1QWZC@1224|Proteobacteria,1RMUS@1236|Gammaproteobacteria,4668E@72275|Alteromonadaceae 1236|Gammaproteobacteria S Glycosyl-hydrolase 97 N-terminal - - - - - - - - - - - - GH97_C,GH97_N,Glyco_hydro_97 k141_30947_1 218284.CCDN010000006_gene3560 2.7e-87 268.0 COG0477@1|root,COG2814@2|Bacteria,1TSS7@1239|Firmicutes,4HC6A@91061|Bacilli,1ZBCF@1386|Bacillus 91061|Bacilli EGP Transmembrane secretion effector - - - - - - - - - - - - MFS_1 k141_8372_2 997296.PB1_15614 6.33e-149 444.0 COG0608@1|root,COG0608@2|Bacteria,1TPXE@1239|Firmicutes,4H9UP@91061|Bacilli,1ZBAT@1386|Bacillus 91061|Bacilli L Single-stranded-DNA-specific exonuclease RecJ recJ - - ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1,ssDNA-exonuc_C k141_39_1 218284.CCDN010000001_gene985 1.02e-120 350.0 COG1071@1|root,COG1071@2|Bacteria,1TQDG@1239|Firmicutes,4HBEQ@91061|Bacilli,1ZCCJ@1386|Bacillus 91061|Bacilli C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit bfmBAA - 1.2.4.4 ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 M00036 R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00027,RC00627,RC02743,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS07640 E1_dh k141_10722_2 1042377.AFPJ01000036_gene1188 1.38e-28 112.0 COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RN5B@1236|Gammaproteobacteria,465JB@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0436 Aspartate tyrosine aromatic aminotransferase alaA GO:0003674,GO:0003824,GO:0004021,GO:0005488,GO:0006082,GO:0006090,GO:0006520,GO:0006522,GO:0006523,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009078,GO:0009079,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019272,GO:0019752,GO:0019842,GO:0030170,GO:0030632,GO:0032787,GO:0033554,GO:0036094,GO:0042221,GO:0042851,GO:0042852,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046144,GO:0046145,GO:0046394,GO:0046416,GO:0046436,GO:0046437,GO:0046677,GO:0047635,GO:0048037,GO:0050662,GO:0050896,GO:0051716,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.2,2.6.1.66 ko:K14260 ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230 - R00258,R01215 RC00006,RC00008,RC00036 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 k141_34506_1 1279017.AQYJ01000020_gene1320 1.34e-62 195.0 COG0789@1|root,COG0789@2|Bacteria,1RITY@1224|Proteobacteria,1S61S@1236|Gammaproteobacteria,467YX@72275|Alteromonadaceae 1236|Gammaproteobacteria K helix_turn_helix, mercury resistance liuR - - - - - - - - - - - MerR,MerR-DNA-bind,MerR_1 k141_34506_2 1279017.AQYJ01000020_gene1319 9.38e-276 754.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RMMJ@1236|Gammaproteobacteria,46572@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1960 Acyl-CoA dehydrogenases ivd - 1.3.8.4 ko:K00253 ko00280,ko01100,map00280,map01100 M00036 R04095 RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_34506_3 1279017.AQYJ01000020_gene1318 0.0 1002.0 COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,1RNV5@1236|Gammaproteobacteria,464FJ@72275|Alteromonadaceae 1236|Gammaproteobacteria I Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) liuB - 6.4.1.4 ko:K01969 ko00280,ko01100,map00280,map01100 M00036 R04138 RC00367,RC00942 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans k141_34506_4 1279017.AQYJ01000020_gene1317 6.25e-159 449.0 COG1024@1|root,COG1024@2|Bacteria,1MVEC@1224|Proteobacteria,1RP85@1236|Gammaproteobacteria,465S5@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1024 Enoyl-CoA hydratase carnithine racemase liuC - 4.2.1.18 ko:K13766 ko00280,ko01100,map00280,map01100 M00036 R02085 RC02416 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 k141_34506_5 1279017.AQYJ01000020_gene1316 0.0 1003.0 COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,1RM95@1236|Gammaproteobacteria,465G3@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG4770 Acetyl propionyl-CoA carboxylase, alpha subunit mccA - 6.4.1.4 ko:K01968 ko00280,ko01100,map00280,map01100 M00036 R04138 RC00367,RC00942 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2 k141_28580_1 701176.VIBRN418_00330 3.24e-162 466.0 COG1479@1|root,COG1479@2|Bacteria,1R63V@1224|Proteobacteria,1S30N@1236|Gammaproteobacteria,1XZ1F@135623|Vibrionales 135623|Vibrionales S Protein of unknown function DUF262 - - - - - - - - - - - - DUF262 k141_5986_1 234267.Acid_3874 6.75e-74 235.0 COG3185@1|root,COG3185@2|Bacteria,3Y2XN@57723|Acidobacteria 57723|Acidobacteria E Acyclic terpene utilisation family protein AtuA - - - - - - - - - - - - AtuA k141_22621_1 218284.CCDN010000001_gene1401 3.99e-189 533.0 COG0006@1|root,COG0006@2|Bacteria,1V22K@1239|Firmicutes,4HTV2@91061|Bacilli,1ZNEY@1386|Bacillus 91061|Bacilli E Metallopeptidase family M24 - - - - - - - - - - - - - k141_20235_1 1348635.BBJY01000016_gene3972 1.5e-81 254.0 COG2160@1|root,COG2160@2|Bacteria,1MW0J@1224|Proteobacteria,1RQEF@1236|Gammaproteobacteria,1XSFJ@135623|Vibrionales 135623|Vibrionales G Catalyzes the conversion of L-arabinose to L-ribulose araA - 5.3.1.4 ko:K01804 ko00040,ko01100,map00040,map01100 - R01761 RC00516 ko00000,ko00001,ko01000 - - - Arabinose_Iso_C,Arabinose_Isome k141_20235_2 1348635.BBJY01000016_gene3973 3.15e-84 252.0 2AW95@1|root,31N4G@2|Bacteria,1QJVY@1224|Proteobacteria,1THXK@1236|Gammaproteobacteria,1XXUB@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_2411_1 1195246.AGRI_09615 1.13e-37 143.0 COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,465WS@72275|Alteromonadaceae 1236|Gammaproteobacteria E Gamma-glutamyltranspeptidase ggt_2 - 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept k141_19050_1 1294265.JCM21738_3891 1.07e-77 240.0 COG2706@1|root,COG2706@2|Bacteria,1TQ3J@1239|Firmicutes,4HBHB@91061|Bacilli,1ZANH@1386|Bacillus 91061|Bacilli G 6-phosphogluconolactonase pgl GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016787,GO:0016788,GO:0017057,GO:0044424,GO:0044444,GO:0044464,GO:0052689 3.1.1.31 ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R02035 RC00537 ko00000,ko00001,ko00002,ko01000 - - - Lactonase k141_8373_1 218284.CCDN010000001_gene1274 6.64e-102 303.0 COG1273@1|root,COG1273@2|Bacteria,1TSY5@1239|Firmicutes,4HC5V@91061|Bacilli,1ZB9J@1386|Bacillus 91061|Bacilli L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD ku GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0097159,GO:1901363 - ko:K10979 ko03450,map03450 - - - ko00000,ko00001,ko03400 - - - Ku k141_26198_1 1116375.VEJY3_13875 4.45e-279 771.0 COG4972@1|root,COG4972@2|Bacteria,1QYK2@1224|Proteobacteria,1T3RJ@1236|Gammaproteobacteria,1Y36D@135623|Vibrionales 135623|Vibrionales NU Pilus assembly protein - - - ko:K12279 - - - - ko00000,ko02044 - - - - k141_26198_2 1116375.VEJY3_13870 4.14e-64 202.0 COG3167@1|root,COG3167@2|Bacteria,1N1KE@1224|Proteobacteria,1S8XS@1236|Gammaproteobacteria,1XWVJ@135623|Vibrionales 135623|Vibrionales NU Pilus assembly protein, PilO mshJ - - ko:K12280 - - - - ko00000,ko02044 - - - PilO,T2SSM k141_34507_1 441769.ABFU01000066_gene1960 4.84e-10 57.8 COG0526@1|root,COG0526@2|Bacteria,1V3YC@1239|Firmicutes,4HJ8N@91061|Bacilli,1ZH2W@1386|Bacillus 91061|Bacilli CO Thioredoxin bdbA - - - - - - - - - - - Thioredoxin k141_28581_2 1403819.BATR01000164_gene5646 1.54e-21 87.0 COG2261@1|root,COG2261@2|Bacteria,46YR6@74201|Verrucomicrobia,2IW8G@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Transglycosylase associated protein - - - - - - - - - - - - Transgly_assoc k141_13124_2 1116375.VEJY3_07820 0.0 1044.0 COG1629@1|root,COG4771@2|Bacteria,1MUPZ@1224|Proteobacteria,1RMMP@1236|Gammaproteobacteria,1XSP3@135623|Vibrionales 135623|Vibrionales M COG1629 Outer membrane receptor proteins, mostly Fe transport iutA - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_41_1 666686.B1NLA3E_16010 2.2e-14 75.1 2ECSV@1|root,336QF@2|Bacteria,1VFWG@1239|Firmicutes,4HP8Y@91061|Bacilli,1ZIWT@1386|Bacillus 91061|Bacilli S YqfQ-like protein yqfQ - - - - - - - - - - - YqfQ k141_26199_1 1042377.AFPJ01000012_gene1398 2.38e-26 105.0 COG4531@1|root,COG4531@2|Bacteria,1QTTI@1224|Proteobacteria,1RMRJ@1236|Gammaproteobacteria,467GB@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG4531 ABC-type Zn2 transport system, periplasmic component surface adhesin znuA - - ko:K09815 ko02010,map02010 M00242 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15.3,3.A.1.15.5 - - ZnuA k141_14304_1 414996.IL38_18775 1.65e-22 91.7 COG1917@1|root,COG1917@2|Bacteria,2IFAP@201174|Actinobacteria,40A51@622450|Actinopolysporales 201174|Actinobacteria S Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant ectC - 4.2.1.108 ko:K06720 ko00260,ko01100,ko01120,map00260,map01100,map01120 M00033 R06979 RC01729 ko00000,ko00001,ko00002,ko01000 - - - Ectoine_synth k141_14304_2 1342299.Z947_4060 3.14e-48 161.0 COG1670@1|root,COG1670@2|Bacteria,1MXEE@1224|Proteobacteria,2U62V@28211|Alphaproteobacteria,3ZUTJ@60136|Sulfitobacter 28211|Alphaproteobacteria J Acetyltransferase (GNAT) domain - GO:0003674,GO:0003824,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747 - - - - - - - - - - Acetyltransf_3 k141_22622_1 1298865.H978DRAFT_1336 1.12e-36 129.0 2A28G@1|root,30QJ6@2|Bacteria,1RDS3@1224|Proteobacteria,1S447@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - SnoaL_2 k141_8374_1 1294265.JCM21738_3406 3.58e-205 586.0 COG0674@1|root,COG1013@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,1TPF0@1239|Firmicutes,4HCVY@91061|Bacilli,1ZBTS@1386|Bacillus 91061|Bacilli C COG0674 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, alpha subunit porA - 1.2.7.1 ko:K00169 ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200 M00173,M00307,M00374,M00620 R01196,R01199,R08034 RC00004,RC00250,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - PFOR_II,POR_N,TPP_enzyme_C k141_13125_1 1294265.JCM21738_4561 9.4e-116 342.0 COG1686@1|root,COG1686@2|Bacteria,1TQN0@1239|Firmicutes,4HBD4@91061|Bacilli,1ZAS6@1386|Bacillus 91061|Bacilli M Belongs to the peptidase S11 family dacA GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0009002,GO:0016787,GO:0017171,GO:0019538,GO:0030312,GO:0043170,GO:0044238,GO:0044464,GO:0070008,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.16.4 ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - PBP5_C,Peptidase_S11 k141_30948_2 1279017.AQYJ01000026_gene180 7.41e-71 214.0 COG0292@1|root,COG0292@2|Bacteria,1RGU2@1224|Proteobacteria,1S3P3@1236|Gammaproteobacteria,466ZJ@72275|Alteromonadaceae 1236|Gammaproteobacteria J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit rplT GO:0000027,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2000113,GO:2001141 - ko:K02887 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L20 k141_28582_2 218284.CCDN010000007_gene3841 3e-190 531.0 COG0042@1|root,COG0042@2|Bacteria,1TQ2R@1239|Firmicutes,4HA9K@91061|Bacilli,1ZBSF@1386|Bacillus 91061|Bacilli J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines dus - - - - - - - - - - - Dus k141_24983_1 218284.CCDN010000001_gene1874 2.2e-101 300.0 COG0329@1|root,COG0329@2|Bacteria,1TPCK@1239|Firmicutes,4H9K9@91061|Bacilli,1ZBNR@1386|Bacillus 91061|Bacilli E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) dapA - 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS k141_33323_1 1279017.AQYJ01000020_gene1331 2.88e-13 67.8 COG0454@1|root,COG0456@2|Bacteria,1NGUX@1224|Proteobacteria,1SV6D@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Acetyltransferase (GNAT) family - - - - - - - - - - - - - k141_35704_1 1116375.VEJY3_07045 0.0 936.0 COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,1RMU1@1236|Gammaproteobacteria,1XSCH@135623|Vibrionales 135623|Vibrionales L COG1643 HrpA-like helicases hrpA - 3.6.4.13 ko:K03578 - - - - ko00000,ko01000 - - - DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind k141_15500_1 223926.28808072 6.12e-32 121.0 COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,1RMN6@1236|Gammaproteobacteria,1XUGG@135623|Vibrionales 135623|Vibrionales P Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA trkH-1 - - ko:K03498 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkH k141_15500_2 1116375.VEJY3_15345 9.16e-100 293.0 2CX2C@1|root,32T0Z@2|Bacteria,1N40Z@1224|Proteobacteria,1SA1U@1236|Gammaproteobacteria,1XWT6@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF3157) - - - - - - - - - - - - DUF3157 k141_15500_3 1116375.VEJY3_15350 1.88e-141 400.0 COG1272@1|root,COG1272@2|Bacteria,1PGRH@1224|Proteobacteria,1RR4R@1236|Gammaproteobacteria,1XT5P@135623|Vibrionales 135623|Vibrionales S membrane protein, hemolysin III hlyIII - - ko:K11068 - - - - ko00000,ko02042 - - - HlyIII k141_15500_4 674977.VMC_25060 1.8e-186 519.0 COG4326@1|root,COG4326@2|Bacteria,1RB4P@1224|Proteobacteria,1S3CE@1236|Gammaproteobacteria,1XTH8@135623|Vibrionales 135623|Vibrionales S COG4326 Sporulation control protein spoOM - - ko:K06377 - - - - ko00000 - - - Spo0M k141_15500_5 1280001.BAOA01000052_gene1637 9.8e-57 176.0 COG3084@1|root,COG3084@2|Bacteria,1N026@1224|Proteobacteria,1S93G@1236|Gammaproteobacteria,1XXV3@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria yihD - - ko:K09896 - - - - ko00000 - - - DUF1040 k141_15500_6 1116375.VEJY3_15370 0.0 909.0 COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,1RMDI@1236|Gammaproteobacteria,1XSG4@135623|Vibrionales 135623|Vibrionales C IG-like fold at C-terminal of FixG, putative oxidoreductase fixG - - - - - - - - - - - Fer4_18,Fer4_5,FixG_C k141_15500_7 1280001.BAOA01000052_gene1635 2.65e-239 657.0 COG2334@1|root,COG2334@2|Bacteria,1MU2Q@1224|Proteobacteria,1RNHI@1236|Gammaproteobacteria,1XU7N@135623|Vibrionales 135623|Vibrionales F A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response srkA - - - - - - - - - - - APH k141_15500_8 1280001.BAOA01000052_gene1634 3.68e-126 360.0 COG1651@1|root,COG1651@2|Bacteria,1RGWH@1224|Proteobacteria,1S5WA@1236|Gammaproteobacteria,1XTXK@135623|Vibrionales 135623|Vibrionales O Thiol disulfide interchange protein dsbA GO:0003674,GO:0003756,GO:0003824,GO:0005575,GO:0005623,GO:0006457,GO:0008150,GO:0009987,GO:0016853,GO:0016860,GO:0016864,GO:0042597,GO:0044464,GO:0140096 - ko:K03673 ko01503,map01503 M00728 - - ko00000,ko00001,ko00002,ko03110 - - - DSBA k141_15500_9 223926.28808081 4.38e-159 449.0 COG0204@1|root,COG0204@2|Bacteria,1MVWG@1224|Proteobacteria,1RR21@1236|Gammaproteobacteria,1XTJU@135623|Vibrionales 135623|Vibrionales I 1-acyl-sn-glycerol-3-phosphate acyltransferase - - - - - - - - - - - - Acyltransferase k141_3614_1 1294265.JCM21738_3443 5.71e-108 324.0 COG0840@1|root,COG0840@2|Bacteria,1TPI1@1239|Firmicutes,4HADY@91061|Bacilli,1ZD20@1386|Bacillus 91061|Bacilli NT Chemotaxis mcpA - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal k141_4799_2 1279017.AQYJ01000025_gene567 2.22e-308 874.0 COG1629@1|root,COG4771@2|Bacteria,1N6JG@1224|Proteobacteria,1RP10@1236|Gammaproteobacteria,465FE@72275|Alteromonadaceae 1236|Gammaproteobacteria P Carboxypeptidase regulatory-like domain - - - - - - - - - - - - CarboxypepD_reg,Plug,TonB_dep_Rec k141_32119_2 218284.CCDN010000001_gene752 1.54e-85 252.0 COG0295@1|root,COG0295@2|Bacteria,1V6IP@1239|Firmicutes,4HIJ3@91061|Bacilli,1ZG79@1386|Bacillus 91061|Bacilli F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis cdd GO:0003674,GO:0003824,GO:0004126,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006216,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009116,GO:0009119,GO:0009164,GO:0009972,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0019439,GO:0034641,GO:0034655,GO:0034656,GO:0042454,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046087,GO:0046131,GO:0046133,GO:0046135,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901657,GO:1901658 3.5.4.5 ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R01878,R02485,R08221 RC00074,RC00514 ko00000,ko00001,ko01000 - - iYO844.BSU25300 dCMP_cyt_deam_1 k141_8377_1 1121940.AUDZ01000014_gene1164 6.92e-11 61.6 COG1043@1|root,COG1043@2|Bacteria,1MUHQ@1224|Proteobacteria,1RPHB@1236|Gammaproteobacteria,1XHDF@135619|Oceanospirillales 135619|Oceanospirillales M Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxA - 2.3.1.129 ko:K00677 ko00540,ko01100,ko01503,map00540,map01100,map01503 M00060 R04567 RC00039,RC00055 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Acetyltransf_11,Hexapep k141_8377_2 671143.DAMO_1650 1.14e-30 114.0 COG0764@1|root,COG0764@2|Bacteria,2NPK9@2323|unclassified Bacteria 2|Bacteria I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs fabZ - 3.5.1.108,4.2.1.59 ko:K02372,ko:K16363 ko00061,ko00540,ko00780,ko01100,ko01212,map00061,map00540,map00780,map01100,map01212 M00060,M00083,M00572 R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965,R07764,R10117,R10121 RC00166,RC00300,RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004,ko01005 - - - FabA k141_30949_1 265729.GS18_0216035 1.03e-24 97.1 2EA57@1|root,334A4@2|Bacteria,1VHEA@1239|Firmicutes,4HQZU@91061|Bacilli,1ZIXN@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_30949_2 666686.B1NLA3E_22000 2.66e-41 141.0 COG0673@1|root,COG0673@2|Bacteria,1UZRV@1239|Firmicutes,4HEWB@91061|Bacilli,1ZE5A@1386|Bacillus 91061|Bacilli S dehydrogenases and related proteins ysjB - - ko:K03810 - - - - ko00000 - - - GFO_IDH_MocA k141_4800_1 279010.BL03321 8.37e-36 136.0 COG2211@1|root,COG2211@2|Bacteria,1UI0Q@1239|Firmicutes,4HENG@91061|Bacilli,1ZBFT@1386|Bacillus 91061|Bacilli G Transmembrane secretion effector - - - - - - - - - - - - MFS_3 k141_34524_1 1033734.CAET01000074_gene2827 1.47e-20 89.0 COG0596@1|root,COG0596@2|Bacteria,1TS4C@1239|Firmicutes,4HB6G@91061|Bacilli,1ZAU9@1386|Bacillus 91061|Bacilli S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) menH GO:0003674,GO:0003824,GO:0016787 4.2.99.20 ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R08166 RC02148,RC02475 ko00000,ko00001,ko00002,ko01000 - - - Abhydrolase_1 k141_34524_2 1347086.CCBA010000039_gene4736 2.91e-43 157.0 COG1165@1|root,COG1165@2|Bacteria,1TRDB@1239|Firmicutes,4HC48@91061|Bacilli,1ZANU@1386|Bacillus 91061|Bacilli H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) menD - 2.2.1.9 ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R08165 RC02186 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS05085 TPP_enzyme_C,TPP_enzyme_M_2,TPP_enzyme_N k141_15528_1 1122211.JMLW01000008_gene2002 4.24e-36 129.0 COG0179@1|root,COG0179@2|Bacteria,1MVFA@1224|Proteobacteria,1RN6Y@1236|Gammaproteobacteria,1XJB7@135619|Oceanospirillales 135619|Oceanospirillales Q Fumarylacetoacetate (FAA) hydrolase - - - - - - - - - - - - FAA_hydrolase k141_15528_2 1453501.JELR01000002_gene1506 4.5e-264 727.0 COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,1RPEY@1236|Gammaproteobacteria,464BH@72275|Alteromonadaceae 1236|Gammaproteobacteria EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family serA GO:0003674,GO:0003824,GO:0004617,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008219,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0012501,GO:0016053,GO:0016491,GO:0016597,GO:0016614,GO:0016616,GO:0019752,GO:0031406,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0047545,GO:0055114,GO:0070905,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - iYL1228.KPN_03348 2-Hacid_dh,2-Hacid_dh_C,ACT k141_26217_1 1347087.CBYO010000022_gene3806 1.05e-51 167.0 COG2816@1|root,COG2816@2|Bacteria,1V5G3@1239|Firmicutes,4HH9P@91061|Bacilli 91061|Bacilli L DNA mismatch repair protein MutT - - - - - - - - - - - - NUDIX k141_11930_1 1294265.JCM21738_2367 3.5e-42 139.0 2DQW9@1|root,3391K@2|Bacteria,1VEHA@1239|Firmicutes,4HNSR@91061|Bacilli,1ZKJR@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_20256_1 218284.CCDN010000001_gene67 1.35e-85 276.0 COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,4HAWB@91061|Bacilli,1ZAQK@1386|Bacillus 91061|Bacilli J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS - 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1,zf-FPG_IleRS k141_34525_1 218284.CCDN010000001_gene519 1e-118 349.0 COG0538@1|root,COG0538@2|Bacteria,1UHPE@1239|Firmicutes,4H9US@91061|Bacilli,1ZBWV@1386|Bacillus 91061|Bacilli C isocitrate icd - 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh k141_1356_1 1385514.N782_01275 7.4e-47 165.0 COG4533@1|root,COG4533@2|Bacteria,1TRY2@1239|Firmicutes,4HBZ3@91061|Bacilli,2YB65@289201|Pontibacillus 91061|Bacilli S Sugar transport-related sRNA regulator N-term - - - - - - - - - - - - SBP_bac_5,SgrR_N k141_28780_1 218284.CCDN010000002_gene2042 9.51e-103 304.0 COG1131@1|root,COG1131@2|Bacteria,1TPQW@1239|Firmicutes,4HA3P@91061|Bacilli,1ZCNQ@1386|Bacillus 91061|Bacilli V ABC transporter, ATP-binding protein potA5 - - ko:K01990,ko:K16921 ko02010,map02010 M00254,M00584 - - ko00000,ko00001,ko00002,ko02000 3.A.1 - - ABC_tran k141_3811_1 1116375.VEJY3_08015 5.54e-110 330.0 COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,1RPNE@1236|Gammaproteobacteria,1XSHH@135623|Vibrionales 135623|Vibrionales I AMP-binding enzyme - - - - - - - - - - - - AMP-binding k141_3811_2 223926.28806723 2.51e-55 177.0 COG1022@1|root,COG1022@2|Bacteria,1QV90@1224|Proteobacteria,1T2AG@1236|Gammaproteobacteria,1XVNZ@135623|Vibrionales 135623|Vibrionales I Iron-containing redox enzyme - - - - - - - - - - - - Haem_oxygenas_2 k141_25163_1 545693.BMQ_4286 8.59e-10 60.5 COG1893@1|root,COG1893@2|Bacteria,1V1NJ@1239|Firmicutes,4HFWT@91061|Bacilli,1ZQAB@1386|Bacillus 91061|Bacilli H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid panE GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008677,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU15110 ApbA,ApbA_C k141_14489_1 1279017.AQYJ01000029_gene3427 1.55e-26 102.0 COG3011@1|root,COG3011@2|Bacteria,1N0YV@1224|Proteobacteria,1S9QH@1236|Gammaproteobacteria,46DJQ@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function, DUF393 yuxK - - - - - - - - - - - DUF393 k141_2612_2 218284.CCDN010000002_gene2146 2.24e-93 284.0 COG0026@1|root,COG0026@2|Bacteria,1TTDR@1239|Firmicutes,4HDHY@91061|Bacilli 91061|Bacilli F Carboxylate--amine ligase - - - - - - - - - - - - ATP-grasp_4 k141_29880_2 315750.BPUM_2688 2.43e-24 94.0 2EA0D@1|root,32SFQ@2|Bacteria,1VJ7K@1239|Firmicutes,4HPZ6@91061|Bacilli,1ZR94@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2584) ytmB - - - - - - - - - - - DUF2584 k141_19190_1 666686.B1NLA3E_06410 1.05e-106 317.0 COG0331@1|root,COG0331@2|Bacteria,1TPB7@1239|Firmicutes,4HBCU@91061|Bacilli,1ZBGQ@1386|Bacillus 91061|Bacilli I malonyl CoA-acyl carrier protein transacylase fabD - 2.3.1.39 ko:K00645 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082 R01626,R11671 RC00004,RC00039,RC02727 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyl_transf_1 k141_16830_1 218284.CCDN010000001_gene101 1.01e-48 160.0 2C8MW@1|root,305IT@2|Bacteria,1V5HI@1239|Firmicutes,4HGP6@91061|Bacilli,1ZBX1@1386|Bacillus 91061|Bacilli S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains ylbO - - ko:K06314 - - - - ko00000,ko03000 - - - Myb_DNA-bind_6 k141_16830_2 218284.CCDN010000001_gene102 1.53e-51 169.0 COG1024@1|root,COG1024@2|Bacteria,1UZHP@1239|Firmicutes,4HEEK@91061|Bacilli,1ZB0V@1386|Bacillus 91061|Bacilli I COG1024 Enoyl-CoA hydratase carnithine racemase - - - - - - - - - - - - ECH_1 k141_31161_1 1294265.JCM21738_609 2.89e-115 331.0 COG1827@1|root,COG1827@2|Bacteria,1V6EY@1239|Firmicutes,4HGYB@91061|Bacilli,1ZGFK@1386|Bacillus 91061|Bacilli S small molecule binding protein (contains 3H domain) yrxA - - ko:K07105 - - - - ko00000 - - - 3H,HTH_11 k141_31161_2 1294265.JCM21738_608 5.31e-48 163.0 COG1104@1|root,COG1104@2|Bacteria,1TPYU@1239|Firmicutes,4HA5J@91061|Bacilli,1ZCRY@1386|Bacillus 91061|Bacilli E Cysteine desulfurase nifS - 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - - Aminotran_5 k141_20351_2 218284.CCDN010000001_gene9 3.83e-05 44.7 COG0045@1|root,COG0045@2|Bacteria,1TQG4@1239|Firmicutes,4HA3W@91061|Bacilli,1ZB9P@1386|Bacillus 91061|Bacilli C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit sucC GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 6.2.1.5 ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU16090 ATP-grasp_2,Ligase_CoA k141_12119_1 218284.CCDN010000002_gene2038 2.39e-42 153.0 COG0457@1|root,COG0457@2|Bacteria,1UATF@1239|Firmicutes,4HE1D@91061|Bacilli,1ZBPM@1386|Bacillus 91061|Bacilli S ATPase. Has a role at an early stage in the morphogenesis of the spore coat - - - - - - - - - - - - Dynamin_N,TPR_8 k141_4932_2 1432050.IE4771_CH01831 2.21e-14 71.2 COG2370@1|root,COG2370@2|Bacteria,1N08F@1224|Proteobacteria,2UA0Y@28211|Alphaproteobacteria,4B7VB@82115|Rhizobiaceae 28211|Alphaproteobacteria O HupE / UreJ protein hupE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03192 - - - - ko00000 - - - HupE_UreJ k141_21644_1 1453501.JELR01000001_gene2950 3.27e-182 512.0 COG0189@1|root,COG0189@2|Bacteria,1MVDU@1224|Proteobacteria,1RR7D@1236|Gammaproteobacteria,464QG@72275|Alteromonadaceae 1236|Gammaproteobacteria HJ COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase) PA1766 - - - - - - - - - - - ATPgrasp_ST k141_1357_1 861299.J421_1826 3.35e-136 403.0 COG1858@1|root,COG1858@2|Bacteria,1ZV0F@142182|Gemmatimonadetes 2|Bacteria C Di-haem cytochrome c peroxidase - - 1.11.1.5 ko:K00428 - - - - ko00000,ko01000 - - - CCP_MauG k141_25165_1 1122182.KB903814_gene2928 1.78e-15 80.1 COG0015@1|root,COG0015@2|Bacteria,2GM71@201174|Actinobacteria,4DD22@85008|Micromonosporales 201174|Actinobacteria F Adenylosuccinate lyase C-terminus - - 4.3.2.2,5.5.1.2 ko:K01756,ko:K01857 ko00230,ko00250,ko00362,ko01100,ko01110,ko01120,ko01130,ko01220,map00230,map00250,map00362,map01100,map01110,map01120,map01130,map01220 M00048,M00049 R01083,R03307,R04559 RC00379,RC00444,RC00445,RC00902 ko00000,ko00001,ko00002,ko01000 - - - ADSL_C,Lyase_1 k141_31162_1 1444310.JANV01000146_gene1033 1.14e-117 351.0 COG1621@1|root,COG1621@2|Bacteria,1TPAE@1239|Firmicutes,4H9Y7@91061|Bacilli,1ZE06@1386|Bacillus 91061|Bacilli G Belongs to the glycosyl hydrolase 32 family sacC3 GO:0003674,GO:0003824,GO:0004553,GO:0004564,GO:0005975,GO:0005984,GO:0005985,GO:0005987,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016052,GO:0016787,GO:0016798,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0046352,GO:0071704,GO:1901575 3.2.1.65 ko:K01212 ko00500,map00500 - R05624,R11311 RC03278 ko00000,ko00001,ko01000 - GH32 - Glyco_hydro_32C,Glyco_hydro_32N k141_2614_1 1294265.JCM21738_3163 2.22e-09 60.1 COG0840@1|root,COG0840@2|Bacteria 2|Bacteria NT transmembrane signaling receptor activity - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - 4HB_MCP_1,HAMP,MCPsignal,dCache_1 k141_12120_1 1453501.JELR01000001_gene1943 3.26e-36 134.0 COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,1RNYI@1236|Gammaproteobacteria,4642M@72275|Alteromonadaceae 1236|Gammaproteobacteria M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxD GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 ko:K02536 ko00540,ko01100,map00540,map01100 M00060 R04550 RC00039,RC00166 ko00000,ko00001,ko00002,ko01000,ko01005 - - ic_1306.c0216 Hexapep,Hexapep_2,LpxD k141_26415_1 1385511.N783_00625 3.76e-34 120.0 COG3708@1|root,COG3708@2|Bacteria,1VB3W@1239|Firmicutes,4HKQB@91061|Bacilli,2YBM8@289201|Pontibacillus 91061|Bacilli K Bacterial transcription activator, effector binding domain - - - - - - - - - - - - Cass2,GyrI-like k141_19191_1 649639.Bcell_1227 1.99e-80 241.0 COG1720@1|root,COG1720@2|Bacteria,1TSBR@1239|Firmicutes,4HHKH@91061|Bacilli,1ZGXW@1386|Bacillus 91061|Bacilli S Uncharacterised protein family UPF0066 - - - - - - - - - - - - UPF0066 k141_1358_1 1144275.COCOR_02166 8.13e-63 211.0 COG1858@1|root,COG1858@2|Bacteria,1Q8AH@1224|Proteobacteria,437F8@68525|delta/epsilon subdivisions,2XA2W@28221|Deltaproteobacteria,2YTVR@29|Myxococcales 28221|Deltaproteobacteria C cytochrome C peroxidase - - - - - - - - - - - - - k141_16831_1 218284.CCDN010000001_gene1635 1.67e-145 420.0 COG0860@1|root,COG0860@2|Bacteria,1TSFS@1239|Firmicutes,4HACZ@91061|Bacilli,1ZAV0@1386|Bacillus 91061|Bacilli M stage II sporulation protein P - - - ko:K06385 - - - - ko00000 - - - SpoIIP k141_23962_1 491952.Mar181_2517 3.42e-119 346.0 COG0600@1|root,COG0600@2|Bacteria,1MWDJ@1224|Proteobacteria,1RQ0A@1236|Gammaproteobacteria,1XJ84@135619|Oceanospirillales 135619|Oceanospirillales P Binding-protein-dependent transport system inner membrane component - - - ko:K02050 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - BPD_transp_1 k141_23962_2 491952.Mar181_2518 3.87e-151 431.0 COG1116@1|root,COG1116@2|Bacteria,1MUDV@1224|Proteobacteria,1RNEH@1236|Gammaproteobacteria,1XNXM@135619|Oceanospirillales 135619|Oceanospirillales P ATPases associated with a variety of cellular activities - - - ko:K02049 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - ABC_tran k141_6250_1 218284.CCDN010000002_gene2905 2.55e-10 65.1 COG1664@1|root,COG1664@2|Bacteria,1V6E6@1239|Firmicutes,4HK3W@91061|Bacilli,1ZFY4@1386|Bacillus 91061|Bacilli M COG1664 Integral membrane protein CcmA involved in cell shape determination - - - - - - - - - - - - Bactofilin k141_12121_1 1294265.JCM21738_1438 8.92e-56 181.0 COG0477@1|root,COG2814@2|Bacteria,1UY8I@1239|Firmicutes,4HDBH@91061|Bacilli,1ZEBN@1386|Bacillus 91061|Bacilli EGP COG0477 Permeases of the major facilitator superfamily - - - - - - - - - - - - MFS_1,MFS_3 k141_31163_1 1123248.KB893346_gene46 8.34e-109 337.0 COG2217@1|root,COG2217@2|Bacteria,4NERS@976|Bacteroidetes,1IQ0B@117747|Sphingobacteriia 976|Bacteroidetes P Heavy metal translocating P-type atpase - - 3.6.3.4,3.6.3.54 ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - - E1-E2_ATPase,HMA,Hydrolase k141_9673_1 1219076.N646_4048 1.02e-126 364.0 COG1024@1|root,COG1024@2|Bacteria,1MVEC@1224|Proteobacteria,1RP85@1236|Gammaproteobacteria,1XT8I@135623|Vibrionales 135623|Vibrionales I COG1024 Enoyl-CoA hydratase carnithine racemase - - 4.2.1.18 ko:K13766 ko00280,ko01100,map00280,map01100 M00036 R02085 RC02416 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 k141_9673_2 1116375.VEJY3_18526 0.0 1154.0 COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,1RM95@1236|Gammaproteobacteria,1Y34V@135623|Vibrionales 135623|Vibrionales I Biotin carboxylase, N-terminal domain - - 6.4.1.4 ko:K01968 ko00280,ko01100,map00280,map01100 M00036 R04138 RC00367,RC00942 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2 k141_9673_3 223926.28809430 3.46e-199 554.0 COG0119@1|root,COG0119@2|Bacteria,1MUMX@1224|Proteobacteria,1RMUX@1236|Gammaproteobacteria,1XU1N@135623|Vibrionales 135623|Vibrionales E COG0119 Isopropylmalate homocitrate citramalate synthases - - 4.1.3.4 ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 M00036,M00088 R01360,R08090 RC00502,RC00503,RC01118,RC01946 ko00000,ko00001,ko00002,ko01000 - - - HMGL-like k141_9673_4 1307759.JOMJ01000003_gene2296 4.76e-76 240.0 COG3291@1|root,COG3291@2|Bacteria,1PH0I@1224|Proteobacteria,42ZGZ@68525|delta/epsilon subdivisions,2X10K@28221|Deltaproteobacteria,2MDY0@213115|Desulfovibrionales 28221|Deltaproteobacteria S Pkd domain containing protein - - - - - - - - - - - - VPEP k141_9673_5 1116375.VEJY3_18516 0.0 1030.0 COG1289@1|root,COG1289@2|Bacteria,1MX9H@1224|Proteobacteria,1RMJ4@1236|Gammaproteobacteria,1XZCJ@135623|Vibrionales 135623|Vibrionales S Fusaric acid resistance protein family - - - - - - - - - - - - FUSC k141_9673_6 1116375.VEJY3_18511 4.99e-79 236.0 COG1846@1|root,COG1846@2|Bacteria,1RDGK@1224|Proteobacteria,1S5DJ@1236|Gammaproteobacteria,1XXCA@135623|Vibrionales 135623|Vibrionales K COG1846 Transcriptional regulators - - - ko:K06075 - - - - ko00000,ko03000 - - - MarR k141_9673_7 1248232.BANQ01000059_gene2078 2.42e-68 209.0 COG5646@1|root,COG5646@2|Bacteria,1N03F@1224|Proteobacteria,1SA9M@1236|Gammaproteobacteria,1XX2F@135623|Vibrionales 135623|Vibrionales S Domain of unknown function (DU1801) - - - - - - - - - - - - DUF1801 k141_9673_8 1219080.VEZ01S_40_00050 8.03e-132 380.0 COG2334@1|root,COG2334@2|Bacteria,1RFSV@1224|Proteobacteria,1T13C@1236|Gammaproteobacteria,1Y30P@135623|Vibrionales 135623|Vibrionales S Ecdysteroid kinase - - - - - - - - - - - - APH k141_9673_9 298386.PBPRB1696 7.29e-70 216.0 2E1Y1@1|root,32X6X@2|Bacteria,1N8U6@1224|Proteobacteria,1SED3@1236|Gammaproteobacteria,1XXMR@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_9673_10 1116375.VEJY3_10420 2.21e-200 556.0 COG0189@1|root,COG0189@2|Bacteria,1MX62@1224|Proteobacteria,1RM8B@1236|Gammaproteobacteria,1XT40@135623|Vibrionales 135623|Vibrionales F Belongs to the RimK family - - - ko:K05844 - - - - ko00000,ko01000,ko03009 - - - RimK k141_9673_11 1348635.BBJY01000003_gene3845 4.06e-145 416.0 COG0589@1|root,COG0589@2|Bacteria,1MVZS@1224|Proteobacteria,1S9R4@1236|Gammaproteobacteria,1Y24D@135623|Vibrionales 135623|Vibrionales T Universal stress protein family - - - - - - - - - - - - Usp k141_34668_6 1279017.AQYJ01000029_gene3511 2.29e-106 311.0 COG0625@1|root,COG0625@2|Bacteria,1RA4Y@1224|Proteobacteria,1S2I8@1236|Gammaproteobacteria,466AS@72275|Alteromonadaceae 1236|Gammaproteobacteria O maleylacetoacetate isomerase maiA - 5.2.1.2,5.2.1.4 ko:K01800,ko:K01801 ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120 M00044 R03181,R03868 RC00867 ko00000,ko00001,ko00002,ko01000 - - - GST_C,GST_C_2,GST_C_3,GST_N,GST_N_3 k141_8538_1 1499680.CCFE01000033_gene3933 7.21e-143 416.0 COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,4HAB3@91061|Bacilli,1ZAPP@1386|Bacillus 91061|Bacilli JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity cshA GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 3.6.4.13 ko:K05592 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,Helicase_C k141_8538_2 1294265.JCM21738_2425 9e-163 456.0 COG1647@1|root,COG1647@2|Bacteria,1TVX4@1239|Firmicutes,4HFF2@91061|Bacilli,1ZD8C@1386|Bacillus 91061|Bacilli S COG1647 Esterase lipase - - 3.1.1.1 ko:K03928 - - - - ko00000,ko01000 - - - Abhydrolase_1,Hydrolase_4 k141_3829_2 1453501.JELR01000001_gene2148 1.16e-100 297.0 COG2885@1|root,COG2885@2|Bacteria,1MYBP@1224|Proteobacteria,1RVRF@1236|Gammaproteobacteria,464H3@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the ompA family yiaD - - ko:K12216 - - - - ko00000,ko02044 3.A.7.9.1 - - Gly-zipper_Omp,Gly-zipper_YMGG,OmpA k141_3829_3 1279017.AQYJ01000029_gene3695 1.73e-24 94.0 COG2900@1|root,COG2900@2|Bacteria,1NGFM@1224|Proteobacteria,1SGAM@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Belongs to the SlyX family slyX - - ko:K03745 - - - - ko00000 - - - SlyX k141_3829_4 1453501.JELR01000001_gene2146 4.86e-191 540.0 COG1680@1|root,COG1680@2|Bacteria,1QD0J@1224|Proteobacteria,1RZUZ@1236|Gammaproteobacteria,46CRC@72275|Alteromonadaceae 1236|Gammaproteobacteria V Beta-lactamase estC - - - - - - - - - - - Beta-lactamase k141_3829_5 1279017.AQYJ01000029_gene3693 4.01e-78 235.0 COG2050@1|root,COG2050@2|Bacteria,1RBPE@1224|Proteobacteria,1SCN1@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q PFAM thioesterase superfamily - - - - - - - - - - - - 4HBT k141_29889_1 261726.Q6R4V3_9CAUD 2.11e-141 425.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QJPJ@10662|Myoviridae 10662|Myoviridae S N-acetylmuramoyl-L-alanine amidase activity - GO:0005575,GO:0019012 - - - - - - - - - - - k141_29889_2 261726.Q6R4V2_9CAUD 6.57e-139 410.0 4QAZJ@10239|Viruses,4QX3R@35237|dsDNA viruses no RNA stage,4QPFF@28883|Caudovirales,4QJS9@10662|Myoviridae 10662|Myoviridae S virion assembly - - - - - - - - - - - - - k141_26437_1 1116375.VEJY3_04135 1.26e-151 429.0 COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,1RPKN@1236|Gammaproteobacteria,1XSSJ@135623|Vibrionales 135623|Vibrionales K COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - - - - - - - - - - Response_reg,Trans_reg_C k141_26437_2 1116375.VEJY3_04140 5.41e-309 847.0 COG0642@1|root,COG2205@2|Bacteria,1MUAK@1224|Proteobacteria,1RPP2@1236|Gammaproteobacteria,1XU4B@135623|Vibrionales 135623|Vibrionales T Signal transduction histidine kinase - - - - - - - - - - - - HAMP,HATPase_c,HisKA k141_26437_3 1116375.VEJY3_04145 1.37e-288 789.0 COG1653@1|root,COG1653@2|Bacteria,1MUYE@1224|Proteobacteria,1RRFK@1236|Gammaproteobacteria,1XSZM@135623|Vibrionales 135623|Vibrionales G COG1653 ABC-type sugar transport system, periplasmic component - - - ko:K17315 ko02010,map02010 M00605 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.24,3.A.1.1.30 - - SBP_bac_1,SBP_bac_8 k141_26437_4 1116375.VEJY3_04150 5.78e-215 594.0 COG1175@1|root,COG1175@2|Bacteria,1MU84@1224|Proteobacteria,1S0D0@1236|Gammaproteobacteria,1XU9G@135623|Vibrionales 135623|Vibrionales P COG1175 ABC-type sugar transport systems, permease components - - - ko:K17316 ko02010,map02010 M00605 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.24,3.A.1.1.30 - - BPD_transp_1 k141_9687_1 1042377.AFPJ01000005_gene2448 2.99e-144 414.0 COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,1RNVM@1236|Gammaproteobacteria,465B3@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the pirin family XCC2717 - - ko:K06911 - - - - ko00000 - - - Pirin,Pirin_C k141_9687_2 1279017.AQYJ01000027_gene1841 4.59e-244 679.0 COG0025@1|root,COG0025@2|Bacteria,1MW5T@1224|Proteobacteria,1RPH6@1236|Gammaproteobacteria,464FP@72275|Alteromonadaceae 1236|Gammaproteobacteria P Sodium/hydrogen exchanger family nhaP - - ko:K03316 - - - - ko00000 2.A.36 - - Na_H_Exchanger k141_9687_3 1279017.AQYJ01000027_gene1840 0.0 913.0 COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,1RNVR@1236|Gammaproteobacteria,465MZ@72275|Alteromonadaceae 1236|Gammaproteobacteria P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family kefC - - ko:K03455,ko:K11745,ko:K11747 - - - - ko00000,ko02000 2.A.37,2.A.37.1.1,2.A.37.1.2 - - Na_H_Exchanger,TrkA_N k141_9687_4 203122.Sde_3273 4.67e-06 48.1 COG3751@1|root,COG3751@2|Bacteria,1NG7K@1224|Proteobacteria,1S7QH@1236|Gammaproteobacteria,466EA@72275|Alteromonadaceae 1236|Gammaproteobacteria O Prolyl 4-hydroxylase alpha subunit homologues. - - 1.14.11.2 ko:K00472 ko00330,ko01100,map00330,map01100 - R01252 RC00478 ko00000,ko00001,ko01000 - - - 2OG-FeII_Oxy_3 k141_10881_1 649639.Bcell_1691 3.3e-77 253.0 COG0209@1|root,COG0209@2|Bacteria,1TPFH@1239|Firmicutes,4HA07@91061|Bacilli,1ZCST@1386|Bacillus 91061|Bacilli F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen nrdA - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_lgC,Ribonuc_red_lgN k141_32232_1 1219076.N646_1753 9.1e-32 116.0 COG2854@1|root,COG2854@2|Bacteria,1NKFA@1224|Proteobacteria,1RNJW@1236|Gammaproteobacteria,1XT3S@135623|Vibrionales 135623|Vibrionales Q ABC-type transport system involved in resistance to organic solvents, auxiliary component mlaC - - ko:K07323 ko02010,map02010 M00210 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27.3 - - MlaC k141_32232_2 223926.28807672 1.65e-97 285.0 COG1463@1|root,COG1463@2|Bacteria,1NCUG@1224|Proteobacteria,1RQ0Y@1236|Gammaproteobacteria,1XW1T@135623|Vibrionales 135623|Vibrionales Q abc-type transport system involved in resistance to organic solvents, periplasmic component mlaD - - ko:K02067 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaD k141_32232_3 223926.28807673 3.22e-174 487.0 COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,1RM9H@1236|Gammaproteobacteria,1XSVZ@135623|Vibrionales 135623|Vibrionales Q COG0767 ABC-type transport system involved in resistance to organic solvents, permease component mlaE - - ko:K02066 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaE k141_32232_4 1116375.VEJY3_13665 7.38e-182 507.0 COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,1RMCJ@1236|Gammaproteobacteria,1XVHP@135623|Vibrionales 135623|Vibrionales Q ABC-type transport system involved in resistance to organic solvents, ATPase component mlaF - - ko:K02065 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - ABC_tran,BCA_ABC_TP_C k141_32232_5 1219076.N646_1757 5.11e-200 557.0 COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,1RMRD@1236|Gammaproteobacteria,1XUQS@135623|Vibrionales 135623|Vibrionales P COG0530 Ca2 Na antiporter yrbG - - ko:K07301 - - - - ko00000,ko02000 2.A.19.5 - - Na_Ca_ex k141_32232_6 1116375.VEJY3_13675 8.11e-214 592.0 COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1MUXD@1224|Proteobacteria,1RMT9@1236|Gammaproteobacteria,1XTGN@135623|Vibrionales 135623|Vibrionales M sugar phosphate isomerase involved in capsule formation kdsD - 5.3.1.13 ko:K06041 ko00540,ko01100,map00540,map01100 M00063 R01530 RC00541 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CBS,SIS k141_32232_7 1116375.VEJY3_13680 1.85e-115 332.0 COG3117@1|root,COG3117@2|Bacteria,1RA1Y@1224|Proteobacteria,1SDZE@1236|Gammaproteobacteria,1XSM1@135623|Vibrionales 135623|Vibrionales S Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA lptC - - ko:K11719 - - - - ko00000,ko02000 1.B.42.1 - - LptC k141_32232_8 223926.28807678 3.05e-96 282.0 COG1934@1|root,COG1934@2|Bacteria,1N776@1224|Proteobacteria,1RPM7@1236|Gammaproteobacteria,1XUJY@135623|Vibrionales 135623|Vibrionales S Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm lptA - - ko:K09774 - - - - ko00000,ko02000 1.B.42.1 - - OstA k141_32232_9 1280001.BAOA01000048_gene1856 3.79e-162 455.0 COG1137@1|root,COG1137@2|Bacteria,1MU8M@1224|Proteobacteria,1RPW1@1236|Gammaproteobacteria,1XT67@135623|Vibrionales 135623|Vibrionales S abc transporter atp-binding protein lptB - - ko:K06861 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko01000,ko02000 1.B.42.1 - - ABC_tran,BCA_ABC_TP_C k141_32232_10 1219076.N646_1762 2.8e-311 853.0 COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,1RMY0@1236|Gammaproteobacteria,1XSDB@135623|Vibrionales 135623|Vibrionales K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released rpoN - - ko:K03092 ko02020,ko05111,map02020,map05111 - - - ko00000,ko00001,ko03021 - - - Sigma54_AID,Sigma54_CBD,Sigma54_DBD k141_32232_11 1219076.N646_1763 5.03e-60 185.0 COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,1S8U1@1236|Gammaproteobacteria,1XXWR@135623|Vibrionales 135623|Vibrionales J COG1544 Ribosome-associated protein Y (PSrp-1) yhbH - - ko:K05808 - - - - ko00000,ko03009 - - - Ribosomal_S30AE k141_32232_12 1116375.VEJY3_13705 1.27e-78 235.0 COG1762@1|root,COG1762@2|Bacteria,1RD0E@1224|Proteobacteria,1S668@1236|Gammaproteobacteria,1XWXU@135623|Vibrionales 135623|Vibrionales G Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type) ptsN - - ko:K02806 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 - - - PTS_EIIA_2 k141_32232_13 1116375.VEJY3_13710 5.19e-192 534.0 COG1660@1|root,COG1660@2|Bacteria,1MVX6@1224|Proteobacteria,1RNJX@1236|Gammaproteobacteria,1XSBH@135623|Vibrionales 135623|Vibrionales S Displays ATPase and GTPase activities yhbJ - - ko:K06958 - - - - ko00000,ko03019 - - - ATP_bind_2 k141_32232_14 1219076.N646_1766 1.13e-52 166.0 COG1925@1|root,COG1925@2|Bacteria,1N6RM@1224|Proteobacteria,1SCXX@1236|Gammaproteobacteria,1XYBI@135623|Vibrionales 135623|Vibrionales G COG1925 Phosphotransferase system, HPr-related proteins ptsO GO:0006808,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0050789,GO:0051179,GO:0051234,GO:0065007,GO:0071702 - ko:K08485 ko02060,map02060 - - - ko00000,ko00001,ko02000 - - - PTS-HPr k141_14500_1 218284.CCDN010000008_gene4158 1.73e-77 230.0 2CYE0@1|root,32E8M@2|Bacteria,1V6HF@1239|Firmicutes,4HJJG@91061|Bacilli,1ZI8T@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_25191_1 218284.CCDN010000003_gene2967 4.36e-164 461.0 COG1774@1|root,COG1774@2|Bacteria,1TP1V@1239|Firmicutes,4H9M9@91061|Bacilli,1ZBCK@1386|Bacillus 91061|Bacilli S stage 0 sporulation protein yaaT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - - - - - - - - - - PSP1 k141_7365_1 218284.CCDN010000005_gene3210 7.18e-94 283.0 COG5337@1|root,COG5337@2|Bacteria,1U0PJ@1239|Firmicutes,4HBE4@91061|Bacilli,1ZD5Z@1386|Bacillus 91061|Bacilli M Spore Coat cotH - - ko:K06330 - - - - ko00000 - - - CotH k141_312_1 760568.Desku_0657 1.48e-26 112.0 COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,248YK@186801|Clostridia,2603C@186807|Peptococcaceae 186801|Clostridia L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity mutS2 - - ko:K07456 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_V,Smr k141_2632_1 218284.CCDN010000002_gene2230 8.84e-37 134.0 COG0654@1|root,COG0654@2|Bacteria,1U29G@1239|Firmicutes,4HF0P@91061|Bacilli,1ZE9I@1386|Bacillus 91061|Bacilli CH FAD binding domain - - - - - - - - - - - - FAD_binding_3 k141_18113_1 1307436.PBF_20488 8.9e-188 544.0 COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HACY@91061|Bacilli,1ZB4C@1386|Bacillus 91061|Bacilli O Belongs to the ClpA ClpB family clpC GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 - ko:K03696 ko01100,map01100 - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N,UVR k141_37021_1 218284.CCDN010000001_gene1252 4.35e-164 466.0 COG1228@1|root,COG1228@2|Bacteria,1TPNQ@1239|Firmicutes,4H9VP@91061|Bacilli,1ZBB1@1386|Bacillus 91061|Bacilli Q COG1228 Imidazolonepropionase and related amidohydrolases hutI - - - - - - - - - - - Amidohydro_1,Amidohydro_3 k141_28802_1 218284.CCDN010000004_gene3038 3.02e-41 140.0 COG0705@1|root,COG0705@2|Bacteria,1UYXN@1239|Firmicutes,4HCIU@91061|Bacilli,1ZRQJ@1386|Bacillus 91061|Bacilli S membrane protein (homolog of Drosophila rhomboid) ydcA - 3.4.21.105 ko:K19225 - - - - ko00000,ko01000,ko01002 - - - Rhomboid k141_28802_2 218284.CCDN010000004_gene3037 1.77e-40 136.0 COG0736@1|root,COG0736@2|Bacteria,1VA0T@1239|Firmicutes,4HKBI@91061|Bacilli,1ZI02@1386|Bacillus 91061|Bacilli I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein acpS - 2.7.8.7 ko:K00997 ko00770,map00770 - R01625 RC00002 ko00000,ko00001,ko01000 - - iYO844.BSU04620 ACPS k141_31175_1 1479235.KK366039_gene1511 9.56e-20 84.7 COG1734@1|root,COG1734@2|Bacteria,1N7D8@1224|Proteobacteria,1SCG1@1236|Gammaproteobacteria,1XM1K@135619|Oceanospirillales 135619|Oceanospirillales T COG1734 DnaK suppressor protein - - - ko:K06204 ko02026,map02026 - - - ko00000,ko00001,ko03000,ko03009,ko03021 - - - zf-dskA_traR k141_31175_2 1279017.AQYJ01000028_gene2506 4.18e-147 419.0 COG0289@1|root,COG0289@2|Bacteria,1MUCT@1224|Proteobacteria,1RMCZ@1236|Gammaproteobacteria,464XD@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate dapB GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.17.1.8 ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R04198,R04199 RC00478 ko00000,ko00001,ko00002,ko01000 - - iSbBS512_1146.SbBS512_E0035 DapB_C,DapB_N k141_31175_5 1453501.JELR01000002_gene420 6.86e-245 676.0 COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,1RMAW@1236|Gammaproteobacteria,465QQ@72275|Alteromonadaceae 1236|Gammaproteobacteria F Carbamoyl-phosphate synthetase glutamine chain carA GO:0000050,GO:0003674,GO:0003824,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0032991,GO:0034641,GO:0034654,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0055086,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_1950,iUTI89_1310.UTI89_C0036,ic_1306.c0040 CPSase_sm_chain,GATase k141_26693_1 1116375.VEJY3_23656 2.16e-59 191.0 COG1054@1|root,COG1054@2|Bacteria,1MUFV@1224|Proteobacteria,1RNNU@1236|Gammaproteobacteria,1XTAK@135623|Vibrionales 135623|Vibrionales S Belongs to the UPF0176 family - - - ko:K07146 - - - - ko00000 - - - Rhodanese k141_26693_2 1116375.VEJY3_23661 3.9e-209 578.0 COG4667@1|root,COG4667@2|Bacteria,1PV7M@1224|Proteobacteria,1RRPR@1236|Gammaproteobacteria,1XTNS@135623|Vibrionales 135623|Vibrionales S esterase of the alpha-beta hydrolase superfamily - - - - - - - - - - - - Patatin k141_26693_3 1116375.VEJY3_23666 1.17e-133 380.0 COG2095@1|root,COG2095@2|Bacteria,1MV1C@1224|Proteobacteria,1RPM8@1236|Gammaproteobacteria,1XUAB@135623|Vibrionales 135623|Vibrionales U UPF0056 membrane protein snatA - - ko:K05595 - - - - ko00000,ko02000 2.A.95.1 - - MarC k141_26693_4 1116375.VEJY3_23671 1.64e-151 428.0 COG0778@1|root,COG0778@2|Bacteria,1NIJ8@1224|Proteobacteria,1RMRT@1236|Gammaproteobacteria,1XTEA@135623|Vibrionales 135623|Vibrionales C NAD(P)h-flavin oxidoreductase nfsA - 1.5.1.38 ko:K10678,ko:K19285 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 - R05706,R08014,R08017,R08042 RC00126,RC00250 ko00000,ko00001,ko01000 - - - Nitroreductase k141_12354_1 641107.CDLVIII_1629 2.13e-13 76.6 COG1143@1|root,COG1143@2|Bacteria,1UIAW@1239|Firmicutes,24MKT@186801|Clostridia,36UPD@31979|Clostridiaceae 186801|Clostridia C Polysaccharide pyruvyl transferase - - - - - - - - - - - - PS_pyruv_trans k141_11062_1 768066.HELO_3571 1.17e-15 75.9 COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,1RNPT@1236|Gammaproteobacteria,1XI9U@135619|Oceanospirillales 135619|Oceanospirillales C The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) aceF - 2.3.1.12 ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding k141_11062_2 42565.FP66_09430 2.82e-188 546.0 COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,1RN6K@1236|Gammaproteobacteria,1XHJR@135619|Oceanospirillales 135619|Oceanospirillales C Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) aceE - 1.2.4.1 ko:K00163 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - Transketolase_N k141_23000_2 234267.Acid_0324 3.02e-17 77.0 COG4576@1|root,COG4576@2|Bacteria 2|Bacteria CQ ethanolamine utilization protein EutN carboxysome structural protein Ccml eutN GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716 - ko:K04028 - - - - ko00000 - - - EutN_CcmL k141_23000_3 1419583.V466_00485 0.000224 46.2 COG0274@1|root,COG0274@2|Bacteria,1N8AG@1224|Proteobacteria,1RRV3@1236|Gammaproteobacteria,1YSNS@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria F DeoC/LacD family aldolase deoC GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4 ko:K01619 ko00030,map00030 - R01066 RC00436,RC00437 ko00000,ko00001,ko01000 - - - DeoC k141_33643_1 1453501.JELR01000002_gene132 1.48e-110 350.0 COG0591@1|root,COG0784@1|root,COG4191@1|root,COG0591@2|Bacteria,COG0784@2|Bacteria,COG4191@2|Bacteria,1QTSW@1224|Proteobacteria,1T1G2@1236|Gammaproteobacteria,46D5M@72275|Alteromonadaceae 1236|Gammaproteobacteria T PAS fold - - - - - - - - - - - - HATPase_c,HisKA,PAS_4,PAS_7,Response_reg,SSF k141_18236_1 1121938.AUDY01000011_gene594 1.97e-154 443.0 COG3919@1|root,COG3919@2|Bacteria,1TQPN@1239|Firmicutes,4HAB0@91061|Bacilli,3NEMS@45667|Halobacillus 91061|Bacilli S D-ala D-ala ligase C-terminus yxbA - 6.3.1.12 ko:K17810 - - - - ko00000,ko01000 - - - - k141_25325_1 218284.CCDN010000001_gene183 6.02e-142 409.0 COG0491@1|root,COG0491@2|Bacteria,1U9UR@1239|Firmicutes,4HCI8@91061|Bacilli,1ZAQ9@1386|Bacillus 91061|Bacilli S Metallo-beta-lactamase superfamily fprA1 - - - - - - - - - - - Lactamase_B k141_24103_1 1121430.JMLG01000002_gene996 2.85e-24 107.0 COG0768@1|root,COG0768@2|Bacteria,1TQHY@1239|Firmicutes,2480Z@186801|Clostridia,260ZX@186807|Peptococcaceae 186801|Clostridia M Penicillin-binding protein, dimerisation domain mrdA - 3.4.16.4 ko:K05515 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - - PBP_dimer,Transpeptidase k141_4009_2 1279017.AQYJ01000024_gene1012 1.02e-199 579.0 COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,1RQIX@1236|Gammaproteobacteria,4669Y@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0457 FOG TPR repeat - - - - - - - - - - - - TPR_14,TPR_16,TPR_19,TPR_2,TPR_6,TPR_8 k141_11064_1 662755.CRES_0213 1.56e-26 104.0 COG1329@1|root,COG1329@2|Bacteria,2GKSU@201174|Actinobacteria,22JYZ@1653|Corynebacteriaceae 201174|Actinobacteria K to M. xanthus CarD carD GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0040007,GO:0042594,GO:0044419,GO:0050896,GO:0051704,GO:0051716,GO:0071496 - ko:K07736 - - - - ko00000,ko03000 - - - CarD_CdnL_TRCF k141_8704_1 864178.E2ELJ8_9CAUD 2.5e-05 49.7 4QCYA@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QR4R@28883|Caudovirales,4QM2Z@10699|Siphoviridae 10699|Siphoviridae S cell adhesion - - - - - - - - - - - - - k141_20502_1 218284.CCDN010000007_gene3960 2.88e-116 362.0 COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,1TQAD@1239|Firmicutes,4HCMS@91061|Bacilli,1ZBF6@1386|Bacillus 91061|Bacilli EI Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly icmF GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046906,GO:0046983,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 ko:K11942 - - - - ko00000,ko01000 - - - ArgK,B12-binding,MM_CoA_mutase k141_31267_1 1042377.AFPJ01000015_gene1592 2.09e-156 458.0 COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,1RNA5@1236|Gammaproteobacteria,465EX@72275|Alteromonadaceae 1236|Gammaproteobacteria P Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity katG GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.11.1.21 ko:K03782 ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110 - R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906 RC00034,RC00213,RC00767,RC02141 ko00000,ko00001,ko01000 - - - peroxidase k141_15814_1 1042377.AFPJ01000008_gene1968 4.83e-99 298.0 COG4188@1|root,COG4188@2|Bacteria,1NQWE@1224|Proteobacteria,1SMHQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Alpha/beta hydrolase family - - - - - - - - - - - - - k141_13513_1 1499680.CCFE01000016_gene1093 2.25e-148 420.0 COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,4HAYM@91061|Bacilli,1ZBXG@1386|Bacillus 91061|Bacilli D COG1192 ATPases involved in chromosome partitioning soj GO:0008150,GO:0022603,GO:0042173,GO:0042174,GO:0043937,GO:0043939,GO:0045595,GO:0045596,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0065007 - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 k141_13513_2 1294265.JCM21738_3225 3.64e-154 437.0 COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,4H9TB@91061|Bacilli,1ZBDT@1386|Bacillus 91061|Bacilli K Belongs to the ParB family spo0J GO:0005575,GO:0005622,GO:0005623,GO:0007059,GO:0008150,GO:0009295,GO:0009987,GO:0022603,GO:0042173,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0043937,GO:0043938,GO:0044424,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0065007 - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - HTH_3,KorB,ParBc k141_23003_1 1294265.JCM21738_3390 1.28e-105 316.0 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4HB97@91061|Bacilli,1ZBGZ@1386|Bacillus 91061|Bacilli C Belongs to the aldehyde dehydrogenase family - - 1.2.99.10 ko:K22445 - - - - ko00000,ko01000 - - - Aldedh k141_4011_1 1453501.JELR01000001_gene2581 3.12e-34 128.0 COG1597@1|root,COG1597@2|Bacteria,1MY37@1224|Proteobacteria,1RMX9@1236|Gammaproteobacteria,46CFQ@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - - - - - - - - - - DAGK_cat k141_33646_1 3694.POPTR_0004s06320.1 2.64e-06 52.4 COG0515@1|root,KOG0192@2759|Eukaryota,37IJT@33090|Viridiplantae,3GB13@35493|Streptophyta,4JES1@91835|fabids 35493|Streptophyta T Serine threonine-protein kinase - GO:0003674,GO:0003824,GO:0004672,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0035556,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0140096,GO:1901564 - - - - - - - - - - Ank_2,Ank_5,Pkinase_Tyr k141_26697_1 358681.BBR47_52890 2.4e-07 56.2 COG0531@1|root,COG0531@2|Bacteria,1UZ73@1239|Firmicutes,4HE8G@91061|Bacilli,26QE3@186822|Paenibacillaceae 91061|Bacilli E Spore gernimation protein M1-959 - - ko:K06296 - - - - ko00000,ko02000 2.A.3.9.3 - - Spore_permease k141_14587_2 218284.CCDN010000001_gene1034 4.71e-48 157.0 COG1670@1|root,COG1670@2|Bacteria,1V26J@1239|Firmicutes,4HG0M@91061|Bacilli,1ZE5Z@1386|Bacillus 91061|Bacilli J Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_3 k141_29984_1 344747.PM8797T_17087 5.38e-54 183.0 COG2110@1|root,COG2110@2|Bacteria 2|Bacteria P phosphatase homologous to the C-terminal domain of histone macroH2A1 CP_0667 - 3.6.1.13 ko:K01515 ko00230,map00230 - R01054 RC00002 ko00000,ko00001,ko01000 - - - Macro k141_29984_2 866536.Belba_2959 6.35e-46 154.0 2CIQB@1|root,30R27@2|Bacteria,4NZ3V@976|Bacteroidetes 976|Bacteroidetes S MTH538 TIR-like domain (DUF1863) - - - - - - - - - - - - DUF1863 k141_8706_1 1385513.N780_15745 2.53e-64 206.0 2CFXT@1|root,2ZAIF@2|Bacteria,1UZMK@1239|Firmicutes,4HDP0@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - Adenyl_transf,NTP_transf_2 k141_19351_1 1517681.HW45_09845 2.97e-105 317.0 COG1129@1|root,COG1129@2|Bacteria,1MU22@1224|Proteobacteria,1RMCH@1236|Gammaproteobacteria,1XZSK@135623|Vibrionales 135623|Vibrionales G ATPases associated with a variety of cellular activities - - 3.6.3.17 ko:K10441 ko02010,map02010 M00212 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - ABC_tran k141_19351_2 1517681.HW45_09840 2.6e-217 603.0 COG1172@1|root,COG1172@2|Bacteria,1MX7D@1224|Proteobacteria,1TCBB@1236|Gammaproteobacteria,1Y0JV@135623|Vibrionales 135623|Vibrionales G Sugar ABC transporter permease - - - ko:K10440 ko02010,map02010 M00212 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - BPD_transp_2 k141_19351_3 1517681.HW45_09835 2.71e-189 531.0 COG1172@1|root,COG1172@2|Bacteria,1MX7D@1224|Proteobacteria,1TCBA@1236|Gammaproteobacteria,1Y04D@135623|Vibrionales 135623|Vibrionales G Branched-chain amino acid transport system / permease component - - - ko:K10440 ko02010,map02010 M00212 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - BPD_transp_2 k141_32351_1 317619.ANKN01000228_gene983 4.01e-65 224.0 COG0068@1|root,COG0068@2|Bacteria,1G063@1117|Cyanobacteria 1117|Cyanobacteria O Belongs to the carbamoyltransferase HypF family hypF - - ko:K04656 - - - - ko00000 - - - Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF k141_27601_1 29495.EA26_11190 2.14e-82 266.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XSE1@135623|Vibrionales 135623|Vibrionales T COG2202 FOG PAS PAC domain - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - MCPsignal,PAS_3 k141_27601_2 223926.28808690 4.71e-140 396.0 COG0695@1|root,COG0695@2|Bacteria,1RCN6@1224|Proteobacteria,1S6FS@1236|Gammaproteobacteria,1XTRD@135623|Vibrionales 135623|Vibrionales O COG0526 Thiol-disulfide isomerase and thioredoxins - - - - - - - - - - - - Glutaredoxin k141_27601_3 1116375.VEJY3_22001 3.57e-198 553.0 COG3203@1|root,COG3203@2|Bacteria,1R541@1224|Proteobacteria,1RPPR@1236|Gammaproteobacteria,1XTK1@135623|Vibrionales 135623|Vibrionales M COG3203 Outer membrane protein (porin) - - - - - - - - - - - - Porin_4 k141_15815_1 886293.Sinac_6684 8.61e-39 142.0 COG0473@1|root,COG0473@2|Bacteria,2IXJZ@203682|Planctomycetes 203682|Planctomycetes C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate - - 1.1.1.85 ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R00994,R04426,R10052 RC00084,RC00417,RC03036 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh k141_13514_1 218284.CCDN010000001_gene1125 1.51e-164 459.0 COG1290@1|root,COG1290@2|Bacteria,1TP6M@1239|Firmicutes,4H9XV@91061|Bacilli,1ZB3U@1386|Bacillus 91061|Bacilli C COG1290 Cytochrome b subunit of the bc complex qcrB - - ko:K03887 ko00190,ko01100,map00190,map01100 M00151 - - ko00000,ko00001,ko00002 - - - Cytochrome_B k141_13514_2 218284.CCDN010000001_gene1126 2.12e-129 370.0 COG1290@1|root,COG2010@1|root,COG1290@2|Bacteria,COG2010@2|Bacteria,1TRS8@1239|Firmicutes,4H9XH@91061|Bacilli,1ZCZW@1386|Bacillus 91061|Bacilli C Menaquinol-cytochrome c reductase cytochrome b c subunit qcrC - - ko:K03888 ko00190,ko01100,map00190,map01100 M00151 - - ko00000,ko00001,ko00002 - - - Cytochrom_B_C,Cytochrome_CBB3 k141_14588_1 218284.CCDN010000007_gene4010 2.1e-106 311.0 2DSIK@1|root,33GA6@2|Bacteria,1VN6K@1239|Firmicutes,4HSJR@91061|Bacilli,1ZHV5@1386|Bacillus 91061|Bacilli S TATA-box binding ywmB - - - - - - - - - - - DUF1779 k141_11067_1 1453501.JELR01000001_gene3241 3.21e-111 335.0 COG0457@1|root,COG0457@2|Bacteria,1RC07@1224|Proteobacteria,1S36N@1236|Gammaproteobacteria,46864@72275|Alteromonadaceae 1236|Gammaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_8 k141_4012_1 218284.CCDN010000008_gene4192 2.81e-214 601.0 COG0624@1|root,COG0624@2|Bacteria,1TPEG@1239|Firmicutes,4HC14@91061|Bacilli,1ZBI2@1386|Bacillus 91061|Bacilli E Dipeptidase ytjP - 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20 k141_8707_1 1122135.KB893135_gene1011 9.75e-18 90.5 COG2931@1|root,COG4932@1|root,COG2931@2|Bacteria,COG4932@2|Bacteria,1MU7T@1224|Proteobacteria,2U1YP@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q COG2931, RTX toxins and related Ca2 -binding proteins - - - - - - - - - - - - VWA,VWA_2 k141_31278_2 441769.ABFU01000060_gene722 3.81e-40 142.0 2EHES@1|root,33B6Q@2|Bacteria,1VNN8@1239|Firmicutes,4HRDX@91061|Bacilli,1ZFFJ@1386|Bacillus 91061|Bacilli S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) yutC - - - - - - - - - - - Spore_YhcN_YlaJ k141_37147_1 218284.CCDN010000002_gene2596 1.23e-158 457.0 COG4191@1|root,COG4191@2|Bacteria,1UZ9W@1239|Firmicutes,4HDK2@91061|Bacilli,1ZD85@1386|Bacillus 91061|Bacilli T Histidine kinase kinB - 2.7.13.3 ko:K07697 ko02020,map02020 M00485 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - 5TM-5TMR_LYT,HATPase_c,HisKA k141_1514_2 218284.CCDN010000001_gene230 1.27e-43 148.0 28I6D@1|root,2ZAC7@2|Bacteria,1UYC6@1239|Firmicutes,4HFH1@91061|Bacilli,1ZC06@1386|Bacillus 91061|Bacilli S EcsC protein family - - - - - - - - - - - - EcsC k141_13545_1 1042377.AFPJ01000032_gene2780 1.44e-77 233.0 2FAHI@1|root,342RK@2|Bacteria,1NXJ2@1224|Proteobacteria,1SQ04@1236|Gammaproteobacteria 1236|Gammaproteobacteria S COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) - - - - - - - - - - - - - k141_13545_2 1042377.AFPJ01000032_gene2781 1.44e-10 58.9 COG2350@1|root,COG2350@2|Bacteria,1NCHB@1224|Proteobacteria,1SG2M@1236|Gammaproteobacteria,46BI7@72275|Alteromonadaceae 1236|Gammaproteobacteria S YCII-related domain - - - - - - - - - - - - YCII k141_15829_2 1121090.KB894688_gene1679 1.54e-28 111.0 COG0053@1|root,COG0053@2|Bacteria,1TSGY@1239|Firmicutes,4H9WP@91061|Bacilli,1ZAPN@1386|Bacillus 91061|Bacilli P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family yeaB - - - - - - - - - - - Cation_efflux,ZT_dimer k141_12375_1 218284.CCDN010000001_gene710 3.98e-69 213.0 COG1183@1|root,COG1183@2|Bacteria,1TR44@1239|Firmicutes,4HFUP@91061|Bacilli,1ZC3H@1386|Bacillus 91061|Bacilli I Belongs to the CDP-alcohol phosphatidyltransferase class-I family pssA - 2.7.8.8 ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 M00093 R01800 RC00002,RC00017,RC02795 ko00000,ko00001,ko00002,ko01000 - - - CDP-OH_P_transf k141_23023_1 766499.C357_19301 1.94e-65 202.0 COG1846@1|root,COG1846@2|Bacteria,1N0MG@1224|Proteobacteria,2UDDI@28211|Alphaproteobacteria 28211|Alphaproteobacteria K transcriptional MA20_26570 - - ko:K22296 - - - - ko00000,ko03000 - - - MarR,MarR_2 k141_20519_1 246197.MXAN_1675 7.61e-18 88.6 COG2937@1|root,COG3320@1|root,COG3774@1|root,COG2937@2|Bacteria,COG3320@2|Bacteria,COG3774@2|Bacteria 2|Bacteria M pathogenesis plsB - 2.3.1.15,6.2.1.3 ko:K00631,ko:K01897 ko00061,ko00071,ko00561,ko00564,ko01100,ko01110,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map00561,map00564,map01100,map01110,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086,M00089 R00851,R01280,R09380 RC00004,RC00014,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - Acyltransferase,NAD_binding_4,PS_pyruv_trans k141_13546_1 1196029.ALIM01000032_gene1420 4.75e-61 197.0 COG0580@1|root,COG0580@2|Bacteria,1TP4T@1239|Firmicutes,4HAWP@91061|Bacilli,1ZCUB@1386|Bacillus 91061|Bacilli G Belongs to the MIP aquaporin (TC 1.A.8) family glpF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02440 - - - - ko00000,ko02000 1.A.8.1,1.A.8.2 - - MIP k141_6430_1 218284.CCDN010000002_gene2938 1.53e-166 480.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,1ZAY7@1386|Bacillus 91061|Bacilli V ABC transporter ygaD GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702 - ko:K11085 ko02010,map02010 - - - ko00000,ko00001,ko01000,ko02000 3.A.1.106 - - ABC_membrane,ABC_tran k141_4039_1 218284.CCDN010000001_gene103 2.45e-47 155.0 COG1399@1|root,COG1399@2|Bacteria,1VB08@1239|Firmicutes,4HME9@91061|Bacilli,1ZGJH@1386|Bacillus 91061|Bacilli S metal-binding, possibly nucleic acid-binding protein ylbN - - ko:K07040 - - - - ko00000 - - - DUF177 k141_4039_2 665952.HMPREF1015_00729 4.65e-51 173.0 COG1323@1|root,COG1323@2|Bacteria,1TPP2@1239|Firmicutes,4HAZJ@91061|Bacilli,1ZC63@1386|Bacillus 91061|Bacilli S Belongs to the UPF0348 family ylbM - - - - - - - - - - - HIGH_NTase1 k141_29994_1 218284.CCDN010000001_gene1900 3.58e-140 398.0 COG0528@1|root,COG0528@2|Bacteria,1TPXN@1239|Firmicutes,4H9UB@91061|Bacilli,1ZBMW@1386|Bacillus 91061|Bacilli F Catalyzes the reversible phosphorylation of UMP to UDP pyrH - 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 - R00158 RC00002 ko00000,ko00001,ko01000 - - iSB619.SA_RS06240 AA_kinase k141_9907_2 218284.CCDN010000009_gene4270 4.35e-157 444.0 COG0010@1|root,COG0010@2|Bacteria,1TR10@1239|Firmicutes,4HAT5@91061|Bacilli,1ZCJY@1386|Bacillus 91061|Bacilli E Belongs to the arginase family rocF GO:0003674,GO:0003824,GO:0004053,GO:0006082,GO:0006520,GO:0006525,GO:0006807,GO:0008150,GO:0008152,GO:0009064,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 3.5.3.1 ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 M00029,M00134 R00551 RC00024,RC00329 ko00000,ko00001,ko00002,ko01000 - - - Arginase k141_482_1 218284.CCDN010000002_gene2885 8.35e-169 478.0 COG2008@1|root,COG2008@2|Bacteria,1TPZI@1239|Firmicutes,4HAM3@91061|Bacilli,1ZD31@1386|Bacillus 91061|Bacilli E Threonine aldolase - - - - - - - - - - - - Beta_elim_lyase k141_8737_1 42565.FP66_08655 9.15e-137 402.0 COG1404@1|root,COG1404@2|Bacteria 2|Bacteria O Belongs to the peptidase S8 family - - - - - - - - - - - - PPC,Peptidase_M10,SLH k141_17012_1 218284.CCDN010000001_gene81 2.28e-85 257.0 COG3879@1|root,COG3879@2|Bacteria,1V2J7@1239|Firmicutes,4HG14@91061|Bacilli,1ZDER@1386|Bacillus 91061|Bacilli S protein conserved in bacteria ylxX GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - - - - - - - - - - DUF881 k141_19376_1 1279017.AQYJ01000027_gene1889 7.66e-144 413.0 COG1561@1|root,COG1561@2|Bacteria,1MWRA@1224|Proteobacteria,1RMAB@1236|Gammaproteobacteria,464U7@72275|Alteromonadaceae 1236|Gammaproteobacteria S stress-induced protein yicC GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009022,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:0140101,GO:1901360,GO:1901361,GO:1901575 - - - - - - - - - - DUF1732,YicC_N k141_19376_2 1453501.JELR01000002_gene1209 3.99e-147 417.0 COG0689@1|root,COG0689@2|Bacteria,1MVFZ@1224|Proteobacteria,1RNTB@1236|Gammaproteobacteria,464J3@72275|Alteromonadaceae 1236|Gammaproteobacteria J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates rph GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006401,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019439,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 ko:K00989 - - - - ko00000,ko01000,ko03016 - - - RNase_PH,RNase_PH_C k141_28923_1 1294265.JCM21738_1476 2.46e-51 162.0 2CNCH@1|root,32SGT@2|Bacteria,1VDMW@1239|Firmicutes,4HMYB@91061|Bacilli,1ZIW4@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_9908_2 42565.FP66_06920 1.64e-101 295.0 COG0526@1|root,COG0526@2|Bacteria,1RI3N@1224|Proteobacteria,1S5YV@1236|Gammaproteobacteria,1XK8W@135619|Oceanospirillales 135619|Oceanospirillales CO Thiol disulfide interchange protein ccmG - - ko:K02199 - - - - ko00000,ko03110 - - - Redoxin k141_13548_1 218284.CCDN010000004_gene3070 1.55e-15 70.5 2E0UC@1|root,32WBV@2|Bacteria,1VDJ2@1239|Firmicutes,4HKXT@91061|Bacilli,1ZJ5C@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2533) ypbS - - - - - - - - - - - DUF2533 k141_26719_2 351348.Maqu_3201 8.71e-253 699.0 COG3328@1|root,COG3328@2|Bacteria,1MU4P@1224|Proteobacteria,1RNB3@1236|Gammaproteobacteria,464M3@72275|Alteromonadaceae 1236|Gammaproteobacteria L Transposase, Mutator family - - - - - - - - - - - - Transposase_mut k141_14603_1 1294265.JCM21738_3114 4.45e-135 390.0 COG1488@1|root,COG1488@2|Bacteria,1TPDW@1239|Firmicutes,4HAI4@91061|Bacilli,1ZCGY@1386|Bacillus 91061|Bacilli H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP pncB - 6.3.4.21 ko:K00763 ko00760,ko01100,map00760,map01100 - R01724 RC00033 ko00000,ko00001,ko01000 - - iYO844.BSU31750 NAPRTase k141_24119_1 218284.CCDN010000001_gene88 4.97e-199 561.0 COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,4H9T1@91061|Bacilli,1ZB77@1386|Bacillus 91061|Bacilli M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan murE GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 ko:K01928 ko00300,ko00550,map00300,map00550 - R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M k141_25347_2 223926.28806184 1.32e-254 701.0 COG4134@1|root,COG4134@2|Bacteria,1MWJ7@1224|Proteobacteria,1RQ0I@1236|Gammaproteobacteria,1XST3@135623|Vibrionales 135623|Vibrionales S transport system periplasmic component - - - ko:K05777 - M00192 - - ko00000,ko00002,ko02000 - - - SBP_bac_8 k141_8739_1 1123288.SOV_3c04300 2.16e-54 182.0 COG3872@1|root,COG3872@2|Bacteria,1TPBU@1239|Firmicutes,4H271@909932|Negativicutes 909932|Negativicutes S Psort location CytoplasmicMembrane, score 10.00 - - - - - - - - - - - - DUF1385 k141_9909_1 935837.JAEK01000036_gene3000 4.24e-09 53.5 2DNMR@1|root,32Y5G@2|Bacteria,1VHJG@1239|Firmicutes,4HNHI@91061|Bacilli,1ZJE7@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_9909_2 1321778.HMPREF1982_01557 7.01e-53 178.0 2DTDV@1|root,33JXB@2|Bacteria,1UIPN@1239|Firmicutes,24WD8@186801|Clostridia 186801|Clostridia S FR47-like protein - - - - - - - - - - - - Acetyltransf_1 k141_29995_1 1294265.JCM21738_4468 2.87e-23 91.3 COG1559@1|root,COG1559@2|Bacteria,1TS48@1239|Firmicutes,4HAUV@91061|Bacilli,1ZC44@1386|Bacillus 91061|Bacilli S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation mltG - - ko:K07082 - - - - ko00000 - - - YceG k141_23027_1 1453501.JELR01000001_gene1966 9.03e-28 112.0 28RR1@1|root,2ZE3K@2|Bacteria,1P7PJ@1224|Proteobacteria,1SUUS@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain present in PSD-95, Dlg, and ZO-1/2. - - - - - - - - - - - - PDZ_2 k141_5115_1 1453501.JELR01000001_gene2283 2.69e-19 84.0 COG1376@1|root,COG1376@2|Bacteria,1Q823@1224|Proteobacteria 1224|Proteobacteria M ErfK ybiS ycfS ynhG family protein - - - - - - - - - - - - YkuD k141_5115_2 1279017.AQYJ01000029_gene3804 0.0 1409.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,1RP3T@1236|Gammaproteobacteria,464NY@72275|Alteromonadaceae 1236|Gammaproteobacteria G Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate ppsA GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008986,GO:0009058,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016781,GO:0019318,GO:0019319,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0071704,GO:1901576 2.7.9.2 ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 M00173,M00374 R00199 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - iEcE24377_1341.EcE24377A_1919,iYL1228.KPN_02160 PEP-utilizers,PEP-utilizers_C,PPDK_N k141_5115_3 1279017.AQYJ01000029_gene3803 2.47e-168 473.0 COG1806@1|root,COG1806@2|Bacteria,1MUHU@1224|Proteobacteria,1RPHX@1236|Gammaproteobacteria,465QN@72275|Alteromonadaceae 1236|Gammaproteobacteria S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation ydiA GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0030234,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0065007,GO:0065009,GO:0098772 2.7.11.33,2.7.4.28 ko:K09773 - - - - ko00000,ko01000 - - - Kinase-PPPase k141_5115_4 1279017.AQYJ01000029_gene3802 9.82e-231 645.0 COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,1RMSE@1236|Gammaproteobacteria,464G9@72275|Alteromonadaceae 1236|Gammaproteobacteria EH COG0147 Anthranilate para-aminobenzoate synthases component I pabB GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.6.1.85 ko:K01665 ko00790,map00790 - R01716 RC00010,RC01418 ko00000,ko00001,ko01000 - - iEC042_1314.EC042_1977 Anth_synt_I_N,Chorismate_bind k141_5115_5 1042377.AFPJ01000007_gene1750 2.41e-39 132.0 2EAR8@1|root,334TE@2|Bacteria,1NDFF@1224|Proteobacteria,1SCX2@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_5115_6 1279017.AQYJ01000029_gene3800 1.71e-215 597.0 COG0583@1|root,COG0583@2|Bacteria,1MU8N@1224|Proteobacteria,1RN7T@1236|Gammaproteobacteria,464YF@72275|Alteromonadaceae 1236|Gammaproteobacteria K Transcriptional regulator cysB GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0097159,GO:1901363 - ko:K13634 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate k141_37287_4 1279017.AQYJ01000027_gene1715 6.82e-146 414.0 COG1657@1|root,COG1657@2|Bacteria,1R3VV@1224|Proteobacteria,1S0Z2@1236|Gammaproteobacteria,469FU@72275|Alteromonadaceae 1236|Gammaproteobacteria I Domain of unknown function (DUF4159) - - - - - - - - - - - - DUF4159 k141_4155_1 42565.FP66_09485 6.5e-29 105.0 COG0425@1|root,COG0425@2|Bacteria,1MZA5@1224|Proteobacteria,1SCFA@1236|Gammaproteobacteria,1XM53@135619|Oceanospirillales 135619|Oceanospirillales O Belongs to the sulfur carrier protein TusA family - - - - - - - - - - - - TusA k141_4155_2 42565.FP66_09490 1.11e-55 187.0 COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,1RP5S@1236|Gammaproteobacteria,1XIIJ@135619|Oceanospirillales 135619|Oceanospirillales S Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state - - - - - - - - - - - - Peptidase_M48,TPR_16,TPR_19 k141_27712_1 42565.FP66_05100 7.07e-90 275.0 COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,1RMD1@1236|Gammaproteobacteria,1XHVZ@135619|Oceanospirillales 135619|Oceanospirillales E highly regulated protein controlled by the addition removal of adenylyl groups by adenylyltransferase from specific tyrosine residues glnA - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C,Gln-synt_N k141_18442_1 218284.CCDN010000001_gene665 5.6e-257 726.0 COG0608@1|root,COG0608@2|Bacteria,1TPXE@1239|Firmicutes,4H9UP@91061|Bacilli,1ZBAT@1386|Bacillus 91061|Bacilli L Single-stranded-DNA-specific exonuclease RecJ recJ - - ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1,ssDNA-exonuc_C k141_13756_1 1117379.BABA_20001 3.06e-08 53.9 294NN@1|root,2ZS1Z@2|Bacteria,1V61K@1239|Firmicutes,4HHXC@91061|Bacilli,1ZB0D@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_13756_2 218284.CCDN010000002_gene2175 1.65e-52 171.0 2BZCW@1|root,32R4U@2|Bacteria,1V7B7@1239|Firmicutes,4HK1P@91061|Bacilli,1ZG24@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF4129) - - - - - - - - - - - - DUF4129 k141_661_1 218284.CCDN010000002_gene2325 4.28e-26 101.0 COG0702@1|root,COG0702@2|Bacteria,1TQFS@1239|Firmicutes,4HDA2@91061|Bacilli,1ZBH3@1386|Bacillus 91061|Bacilli GM NmrA-like family yhfK GO:0005575,GO:0005622,GO:0005623,GO:0044464 - - - - - - - - - - NAD_binding_10 k141_7597_4 1453501.JELR01000001_gene3262 9.48e-151 439.0 COG0810@1|root,COG0810@2|Bacteria,1PEER@1224|Proteobacteria,1RPPU@1236|Gammaproteobacteria,466NW@72275|Alteromonadaceae 1236|Gammaproteobacteria M Chalcone isomerase-like - - - ko:K03832 - - - - ko00000,ko02000 2.C.1.1 - - Chalcone_3,TonB_2,TonB_C k141_7597_5 1042377.AFPJ01000035_gene2653 2.77e-200 577.0 COG3590@1|root,COG3590@2|Bacteria,1MVNQ@1224|Proteobacteria,1RNNA@1236|Gammaproteobacteria,464DA@72275|Alteromonadaceae 1236|Gammaproteobacteria O Peptidase, M13 pepO - 3.4.24.71 ko:K01415,ko:K07386 - - - - ko00000,ko01000,ko01002,ko04147 - - - Peptidase_M13,Peptidase_M13_N k141_11318_1 218284.CCDN010000002_gene2909 6.21e-90 283.0 COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HA0V@91061|Bacilli,1ZBTK@1386|Bacillus 91061|Bacilli O Belongs to the ClpA ClpB family clpE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03697,ko:K04086 - - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,UVR k141_25604_1 1294265.JCM21738_29 2.28e-75 226.0 COG2172@1|root,COG2172@2|Bacteria,1V6V2@1239|Firmicutes,4HGYN@91061|Bacilli,1ZFKS@1386|Bacillus 91061|Bacilli F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition spoIIAB GO:0000003,GO:0000988,GO:0000989,GO:0003674,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 2.7.11.1 ko:K06379 - - - - ko00000,ko01000 - - - HATPase_c_2 k141_23240_1 1219076.N646_1799 2.78e-141 419.0 COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1MUQV@1224|Proteobacteria,1RN0Q@1236|Gammaproteobacteria,1XSFU@135623|Vibrionales 135623|Vibrionales T COG2199 FOG GGDEF domain csrD - - ko:K18765 - - - - ko00000,ko03019 - - - EAL,GAPES4,GGDEF k141_4162_1 1116375.VEJY3_04390 5.7e-141 405.0 COG0687@1|root,COG0687@2|Bacteria,1MUYW@1224|Proteobacteria,1RM7W@1236|Gammaproteobacteria,1XW4V@135623|Vibrionales 135623|Vibrionales E Required for the activity of the bacterial periplasmic transport system of putrescine - - - ko:K11073 ko02010,map02010 M00300 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.2 - - SBP_bac_8 k141_4162_2 1116375.VEJY3_04385 0.0 889.0 COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,1RNW9@1236|Gammaproteobacteria,1XUZX@135623|Vibrionales 135623|Vibrionales E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - 2.6.1.113 ko:K12256 ko00330,ko01100,map00330,map01100 - R08714 RC00008,RC00062 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_3 k141_4162_3 1116375.VEJY3_04380 0.0 889.0 COG0174@1|root,COG0174@2|Bacteria,1MU6V@1224|Proteobacteria,1RPNZ@1236|Gammaproteobacteria,1XU6T@135623|Vibrionales 135623|Vibrionales E Glutamine synthetase, catalytic domain - - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C k141_4162_4 1116375.VEJY3_04375 6.17e-314 857.0 COG0174@1|root,COG0174@2|Bacteria,1MU6V@1224|Proteobacteria,1RPNZ@1236|Gammaproteobacteria,1XVID@135623|Vibrionales 135623|Vibrionales E glutamine synthetase - - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C k141_4162_5 1116375.VEJY3_04370 2.5e-296 810.0 COG0665@1|root,COG0665@2|Bacteria,1MVGP@1224|Proteobacteria,1RNJ9@1236|Gammaproteobacteria,1XSCR@135623|Vibrionales 135623|Vibrionales E COG0665 Glycine D-amino acid oxidases (deaminating) - - - ko:K09471 ko00330,ko01100,map00330,map01100 M00136 R07415 RC00062 ko00000,ko00001,ko00002,ko01000 - - - DAO k141_4162_6 1116375.VEJY3_04365 3.64e-88 271.0 COG2723@1|root,COG2723@2|Bacteria,1MWG6@1224|Proteobacteria,1RMM2@1236|Gammaproteobacteria,1XSV6@135623|Vibrionales 135623|Vibrionales G Belongs to the glycosyl hydrolase 1 family - - 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 - R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 - GT1 - Glyco_hydro_1 k141_12610_1 1167006.UWK_02387 1.76e-73 239.0 COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,43AD6@68525|delta/epsilon subdivisions,2WJCC@28221|Deltaproteobacteria 28221|Deltaproteobacteria P Sulfate transporter antisigma-factor antagonist STAS - - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - STAS,Sulfate_transp k141_15953_2 517418.Ctha_2482 1.29e-48 166.0 COG0451@1|root,COG0451@2|Bacteria,1FDWT@1090|Chlorobi 1090|Chlorobi M short-chain dehydrogenase reductase SDR - - 5.1.3.6 ko:K08679 ko00520,ko01100,map00520,map01100 - R01385 RC00289 ko00000,ko00001,ko01000 - - - Epimerase k141_33832_2 1279017.AQYJ01000026_gene330 1.49e-192 543.0 COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,1RNS1@1236|Gammaproteobacteria,465R6@72275|Alteromonadaceae 1236|Gammaproteobacteria M Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxB GO:0003674,GO:0003824,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008194,GO:0008289,GO:0008610,GO:0008654,GO:0008915,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0019637,GO:0019897,GO:0019898,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 ko:K00748 ko00540,ko01100,map00540,map01100 M00060 R04606 RC00005,RC00059 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT19 iE2348C_1286.E2348C_0187,iEcolC_1368.EcolC_3478 LpxB k141_37304_1 1243664.CAVL020000009_gene640 2.13e-20 90.9 COG1473@1|root,COG1473@2|Bacteria,1TQ7R@1239|Firmicutes,4HB6M@91061|Bacilli,1ZB9M@1386|Bacillus 91061|Bacilli S amidohydrolase - - - ko:K14665 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 k141_37304_2 1307436.PBF_03880 7.75e-33 121.0 COG3375@1|root,COG3375@2|Bacteria,1V21D@1239|Firmicutes,4HG3H@91061|Bacilli,1ZDH1@1386|Bacillus 91061|Bacilli M carboxylic acid catabolic process - - - - - - - - - - - - Acetyltransf_1 k141_14723_1 309800.C498_00445 1.15e-68 219.0 COG1250@1|root,arCOG00250@2157|Archaea,2XT9S@28890|Euryarchaeota,23TDY@183963|Halobacteria 183963|Halobacteria I 3-hydroxyacyl-CoA dehydrogenase hbd3 - 1.1.1.157 ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 - R01976,R05576,R06941 RC00029,RC00117 ko00000,ko00001,ko01000 - - - 3HCDH,3HCDH_N k141_36080_1 1279017.AQYJ01000027_gene1704 3.82e-36 124.0 COG0789@1|root,COG0789@2|Bacteria,1N9MT@1224|Proteobacteria,1SE7J@1236|Gammaproteobacteria,46CFA@72275|Alteromonadaceae 1236|Gammaproteobacteria K MerR HTH family regulatory protein cbpM - - ko:K18997 - - - - ko00000,ko03036 - - - MerR_2 k141_7598_1 1236973.JCM9157_1437 3.03e-78 247.0 COG3291@1|root,COG3291@2|Bacteria,1V0FC@1239|Firmicutes,4HES3@91061|Bacilli,1ZE9N@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF1906) - - - - - - - - - - - - DUF1906 k141_18461_1 474922.ELA24849 2.44e-15 82.8 COG0464@1|root,KOG0737@2759|Eukaryota,39KZG@33154|Opisthokonta,3Q5D5@4751|Fungi,3RNCR@4890|Ascomycota,21RQJ@147550|Sordariomycetes,1F7CY@1028384|Glomerellales 4751|Fungi O Mus7 MMS22 family protein - - - - - - - - - - - - AAA,Mus7 k141_8926_1 1280001.BAOA01000128_gene1189 1.71e-117 347.0 COG3487@1|root,COG3487@2|Bacteria,1MX5H@1224|Proteobacteria,1RPWE@1236|Gammaproteobacteria,1XVTP@135623|Vibrionales 135623|Vibrionales P Iron-regulated protein icmP - - ko:K07231 - - - - ko00000 - - - Peptidase_M75 k141_8926_2 1515746.HR45_16165 1.18e-59 198.0 COG2801@1|root,COG3415@1|root,COG2801@2|Bacteria,COG3415@2|Bacteria,1MWVQ@1224|Proteobacteria,1RN12@1236|Gammaproteobacteria,2QEPQ@267890|Shewanellaceae 1236|Gammaproteobacteria L PFAM Integrase catalytic region - - - - - - - - - - - - HTH_23,HTH_29,rve k141_25606_1 1453501.JELR01000001_gene2367 1.88e-51 179.0 COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,1RMSR@1236|Gammaproteobacteria,4646K@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the peptidase S41A family prc GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016787,GO:0019538,GO:0023052,GO:0030163,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - BAGE,DUF3340,PDZ,Peptidase_S41 k141_23241_1 218284.CCDN010000001_gene460 2.47e-103 324.0 COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1UYA0@1239|Firmicutes,4HD4S@91061|Bacilli,1ZAW5@1386|Bacillus 91061|Bacilli GT phosphoenolpyruvate synthase pps - 2.7.9.2 ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 M00173,M00374 R00199 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - PEP-utilizers,PPDK_N k141_21918_1 1294265.JCM21738_1745 1.73e-104 308.0 COG4294@1|root,COG4294@2|Bacteria,1TTCB@1239|Firmicutes,4H9PY@91061|Bacilli,1ZCJ7@1386|Bacillus 91061|Bacilli L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion uvsE - - ko:K13281 - - - - ko00000,ko01000 - - - UvdE k141_21918_2 1294265.JCM21738_1744 1.21e-26 103.0 COG1502@1|root,COG1502@2|Bacteria,1USPT@1239|Firmicutes,4HCJD@91061|Bacilli,1ZC77@1386|Bacillus 91061|Bacilli I Belongs to the phospholipase D family. Cardiolipin synthase subfamily clsB GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0032048,GO:0032049,GO:0032502,GO:0043934,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 - ko:K06131 ko00564,ko01100,map00564,map01100 - R07390 RC00017 ko00000,ko00001,ko01000 - - - PLDc_2 k141_15954_1 314278.NB231_06066 2.86e-22 100.0 COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,1RMMQ@1236|Gammaproteobacteria,1WW2Y@135613|Chromatiales 135613|Chromatiales L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) recG - 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecG_wedge k141_4163_1 218284.CCDN010000001_gene60 9.32e-125 365.0 COG0044@1|root,COG0044@2|Bacteria,1TPQM@1239|Firmicutes,4HA90@91061|Bacilli,1ZAS7@1386|Bacillus 91061|Bacilli F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily pyrC GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 k141_11319_1 218284.CCDN010000010_gene4388 4.85e-225 628.0 COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,4HAKH@91061|Bacilli,1ZAWK@1386|Bacillus 91061|Bacilli J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) gltX GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0009986,GO:0030246,GO:0030247,GO:0044464,GO:2001065 6.1.1.24 ko:K09698 ko00970,ko01100,map00970,map01100 M00360 R03651,R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iSB619.SA_RS02860 tRNA-synt_1c k141_37305_1 1190603.AJYD01000023_gene754 1.75e-69 231.0 COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,1RNCM@1236|Gammaproteobacteria,1XW94@135623|Vibrionales 135623|Vibrionales C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - 1.3.99.16 ko:K07303 - - - - ko00000,ko01000 - - - Ald_Xan_dh_C2 k141_7599_1 218284.CCDN010000001_gene1080 1.51e-61 196.0 COG1408@1|root,COG1408@2|Bacteria,1V494@1239|Firmicutes,4HH1B@91061|Bacilli,1ZBFW@1386|Bacillus 91061|Bacilli S Calcineurin-like phosphoesterase superfamily domain ypbG - - ko:K07098 - - - - ko00000 - - - Metallophos,Metallophos_2 k141_26916_1 1116375.VEJY3_12910 0.0 989.0 COG1049@1|root,COG1049@2|Bacteria,1MVCR@1224|Proteobacteria,1RNMC@1236|Gammaproteobacteria,1XTKU@135623|Vibrionales 135623|Vibrionales C Belongs to the aconitase IPM isomerase family acnB - 4.2.1.3,4.2.1.99 ko:K01682 ko00020,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173 R01324,R01325,R01900,R04425 RC00497,RC00498,RC00618,RC01153 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_2_N,Aconitase_B_N k141_26916_2 1280001.BAOA01000080_gene3068 1.94e-72 218.0 COG3112@1|root,COG3112@2|Bacteria,1RH38@1224|Proteobacteria,1S6EG@1236|Gammaproteobacteria,1XXP5@135623|Vibrionales 135623|Vibrionales S Belongs to the UPF0231 family yacL - - ko:K09910 - - - - ko00000 - - - UPF0231 k141_26916_3 1280001.BAOA01000059_gene2313 5.42e-72 217.0 COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,1S67I@1236|Gammaproteobacteria,1XXDH@135623|Vibrionales 135623|Vibrionales K Belongs to the P(II) protein family glnK - - ko:K04752 - - - - ko00000 - - - P-II k141_26916_4 223926.28807490 1.85e-283 776.0 COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,1RNKF@1236|Gammaproteobacteria,1XU86@135623|Vibrionales 135623|Vibrionales P COG0004 Ammonia permease amtB - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - Ammonium_transp k141_26916_5 223926.28807489 7.78e-235 647.0 COG1840@1|root,COG1840@2|Bacteria,1MUEG@1224|Proteobacteria,1RQ6Z@1236|Gammaproteobacteria,1XSPA@135623|Vibrionales 135623|Vibrionales P COG1840 ABC-type Fe3 transport system, periplasmic component fbpA - - ko:K02012 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - SBP_bac_6 k141_26916_6 674977.VMC_24520 0.0 1003.0 COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,1RP55@1236|Gammaproteobacteria,1XUVE@135623|Vibrionales 135623|Vibrionales P iron(III) ABC transporter, permease protein fbpB - - ko:K02011 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - BPD_transp_1 k141_26916_7 1116375.VEJY3_12865 5.64e-189 528.0 COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,1RNPX@1236|Gammaproteobacteria,1XUN0@135623|Vibrionales 135623|Vibrionales P Belongs to the ABC transporter superfamily fbpC - 3.6.3.30 ko:K02010 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.10 - - ABC_tran,TOBE_2 k141_36081_1 218284.CCDN010000001_gene1111 1.67e-95 286.0 COG0142@1|root,COG0142@2|Bacteria,1TR0U@1239|Firmicutes,4H9RH@91061|Bacilli,1ZAZ7@1386|Bacillus 91061|Bacilli H Belongs to the FPP GGPP synthase family hepT GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.30,2.5.1.83 ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 - R09245,R09247 RC00279 ko00000,ko00001,ko01000,ko01006 - - - polyprenyl_synt k141_23242_1 1042377.AFPJ01000012_gene1381 9.64e-96 290.0 COG0534@1|root,COG0534@2|Bacteria,1MV6B@1224|Proteobacteria,1RPGF@1236|Gammaproteobacteria,46598@72275|Alteromonadaceae 1236|Gammaproteobacteria V COG0534 Na -driven multidrug efflux pump dinF - - ko:K03327 - - - - ko00000,ko02000 2.A.66.1 - - MatE k141_5367_1 1219076.N646_1217 2.34e-43 142.0 2B6JH@1|root,31ZHW@2|Bacteria,1QKHC@1224|Proteobacteria,1TIMH@1236|Gammaproteobacteria,1XZC5@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_5367_4 870967.VIS19158_03961 5.86e-216 599.0 COG4695@1|root,COG4695@2|Bacteria,1MWA5@1224|Proteobacteria,1RPXY@1236|Gammaproteobacteria,1XTHZ@135623|Vibrionales 135623|Vibrionales S portal protein - - - - - - - - - - - - Phage_portal k141_5367_5 870967.VIS19158_03956 0.0 1129.0 COG4373@1|root,COG4373@2|Bacteria,1MXYV@1224|Proteobacteria,1RMCC@1236|Gammaproteobacteria,1XVE2@135623|Vibrionales 135623|Vibrionales S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_5,Terminase_6,Terminase_6C k141_5367_6 1219076.N646_1214 6.74e-132 382.0 2CAV1@1|root,2ZBY8@2|Bacteria,1RAGI@1224|Proteobacteria,1RYPG@1236|Gammaproteobacteria,1XUV2@135623|Vibrionales 135623|Vibrionales S Phage capsid scaffolding protein (GPO) serine peptidase - - - - - - - - - - - - Phage_GPO k141_5367_7 1219076.N646_1213 3.29e-195 546.0 2CCQ9@1|root,2Z7HY@2|Bacteria,1MUWR@1224|Proteobacteria,1RPKI@1236|Gammaproteobacteria,1XVEW@135623|Vibrionales 135623|Vibrionales S Phage major capsid protein, P2 family - - - - - - - - - - - - Phage_cap_P2 k141_5367_8 870967.VIS19158_03941 3.61e-138 394.0 28IX0@1|root,2Z8V2@2|Bacteria,1R4KA@1224|Proteobacteria,1S4KG@1236|Gammaproteobacteria,1XX74@135623|Vibrionales 135623|Vibrionales L Phage small terminase subunit - - - - - - - - - - - - Phage_term_smal k141_33834_1 1298593.TOL_0379 1.21e-35 139.0 COG0542@1|root,COG0542@2|Bacteria,1MVBH@1224|Proteobacteria,1RMZH@1236|Gammaproteobacteria,1XHS7@135619|Oceanospirillales 135619|Oceanospirillales O Belongs to the ClpA ClpB family - - - ko:K11907 ko02025,ko03070,map02025,map03070 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - AAA,AAA_2,ClpB_D2-small,Clp_N k141_25607_1 218284.CCDN010000004_gene3122 1.14e-131 387.0 COG0415@1|root,COG0415@2|Bacteria,1TQAK@1239|Firmicutes,4HB9K@91061|Bacilli,1ZCI5@1386|Bacillus 91061|Bacilli L Belongs to the DNA photolyase family phrB - 4.1.99.3 ko:K01669 - - - - ko00000,ko01000,ko03400 - - - DNA_photolyase,FAD_binding_7 k141_17132_1 1234664.AMRO01000052_gene161 3.72e-26 105.0 COG0438@1|root,COG0438@2|Bacteria,1UZ24@1239|Firmicutes,4IQ4P@91061|Bacilli,1WG11@129337|Geobacillus 91061|Bacilli M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 k141_17132_2 1234664.AMRO01000052_gene162 4.77e-52 178.0 COG0728@1|root,COG0728@2|Bacteria,1TPFI@1239|Firmicutes,4HDZW@91061|Bacilli,1WG2I@129337|Geobacillus 91061|Bacilli S Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane - - - ko:K03980 - - - - ko00000,ko01011,ko02000 2.A.66.4 - - MVIN k141_4164_1 1177154.Y5S_01706 2.47e-48 177.0 COG1361@1|root,COG1361@2|Bacteria,1QVSF@1224|Proteobacteria 1224|Proteobacteria M domain protein - - - - - - - - - - - - CARDB,DUF11,OmpA_membrane k141_35035_1 1205908.AKXW01000108_gene1225 2.1e-32 125.0 COG0601@1|root,COG1173@1|root,COG0601@2|Bacteria,COG1173@2|Bacteria,1R3VQ@1224|Proteobacteria,1RY4F@1236|Gammaproteobacteria,1XTGP@135623|Vibrionales 135623|Vibrionales P Binding-protein-dependent transport system inner membrane component - - - ko:K02033,ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 k141_35035_2 1280001.BAOA01000027_gene4889 1.11e-307 845.0 COG0747@1|root,COG0747@2|Bacteria,1P1HT@1224|Proteobacteria,1RY88@1236|Gammaproteobacteria,1XV49@135623|Vibrionales 135623|Vibrionales E Bacterial extracellular solute-binding proteins, family 5 Middle - - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 k141_35035_3 1280001.BAOA01000027_gene4890 1.81e-150 430.0 COG4608@1|root,COG4608@2|Bacteria,1NU4K@1224|Proteobacteria,1T515@1236|Gammaproteobacteria,1Y391@135623|Vibrionales 135623|Vibrionales E ATPases associated with a variety of cellular activities - - - - - - - - - - - - ABC_tran k141_675_1 1120970.AUBZ01000003_gene163 7.61e-126 390.0 COG4191@1|root,COG4191@2|Bacteria,1MU55@1224|Proteobacteria,1RQ5N@1236|Gammaproteobacteria,4643T@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0642 Signal transduction histidine kinase prsK - - - - - - - - - - - GAF_2,HATPase_c k141_675_3 46234.ANA_C11815 1.49e-07 58.2 COG0463@1|root,COG0463@2|Bacteria,1G2SR@1117|Cyanobacteria,1HK6X@1161|Nostocales 1117|Cyanobacteria M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 k141_15955_1 218284.CCDN010000001_gene218 1.68e-164 473.0 COG0365@1|root,COG0365@2|Bacteria,1TQTI@1239|Firmicutes,4H9PN@91061|Bacilli,1ZCDC@1386|Bacillus 91061|Bacilli I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases ytcI GO:0003674,GO:0003824,GO:0003996,GO:0004321,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0015645,GO:0016053,GO:0016405,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0016874,GO:0016877,GO:0016878,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901576 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 - - - AMP-binding,AMP-binding_C k141_33835_1 679197.HMPREF9336_01819 8.19e-09 60.1 COG1716@1|root,COG1716@2|Bacteria,2GNU2@201174|Actinobacteria 201174|Actinobacteria T (FHA) domain fhaA GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363 - - - - - - - - - - DUF3662,FHA,Yop-YscD_cpl k141_14725_1 1288826.MSNKSG1_00556 2.84e-154 446.0 COG0055@1|root,COG0055@2|Bacteria,1N6UZ@1224|Proteobacteria,1RNQW@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits - - 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_N k141_11321_1 1234664.AMRO01000050_gene417 1.13e-23 97.4 COG3641@1|root,COG3641@2|Bacteria,1TS5F@1239|Firmicutes,4HC7U@91061|Bacilli 91061|Bacilli S membrane - - - ko:K07035 - - - - ko00000 - - - PTS_EIIC_2 k141_36082_1 1033734.CAET01000029_gene4588 6.19e-89 273.0 COG1404@1|root,COG1404@2|Bacteria,1TSRI@1239|Firmicutes,4HBFB@91061|Bacilli,1ZCQD@1386|Bacillus 91061|Bacilli O Subtilase family - - 3.4.21.62 ko:K01342 ko02024,map02024 - - - ko00000,ko00001,ko01000,ko01002,ko03110 - - - Peptidase_S8 k141_5369_1 1294265.JCM21738_1382 1.12e-35 128.0 COG4221@1|root,COG4221@2|Bacteria,1TQDY@1239|Firmicutes,4HBS5@91061|Bacilli,1ZB88@1386|Bacillus 91061|Bacilli S Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short k141_18463_1 218284.CCDN010000007_gene3827 1.46e-107 329.0 COG4863@1|root,COG4863@2|Bacteria,1UV48@1239|Firmicutes,4HF30@91061|Bacilli,1ZD30@1386|Bacillus 91061|Bacilli S protein conserved in bacteria yycH - - - - - - - - - - - YycH k141_35036_1 1294265.JCM21738_3544 7.89e-69 209.0 COG1622@1|root,COG1622@2|Bacteria,1TPMD@1239|Firmicutes,4HGXU@91061|Bacilli,1ZAWE@1386|Bacillus 91061|Bacilli C COG1622 Heme copper-type cytochrome quinol oxidases, subunit 2 cbaB - 1.9.3.1 ko:K02275 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.4,3.D.4.6 - - COX2 k141_35036_2 1294265.JCM21738_3545 1.15e-36 135.0 COG0843@1|root,COG0843@2|Bacteria,1TRC2@1239|Firmicutes,4HDTI@91061|Bacilli,1ZR6V@1386|Bacillus 91061|Bacilli C COG0843 Heme copper-type cytochrome quinol oxidases, subunit 1 - - 1.9.3.1 ko:K02274 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6 - - COX1 k141_25608_1 218284.CCDN010000010_gene4369 2.86e-174 503.0 COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,4HAB8@91061|Bacilli,1ZBS4@1386|Bacillus 91061|Bacilli J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome fusA - - ko:K02355 - - - - ko00000,ko03012,ko03029 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 k141_26919_2 218284.CCDN010000001_gene511 2.39e-76 234.0 COG0777@1|root,COG0777@2|Bacteria,1TP4U@1239|Firmicutes,4HAI7@91061|Bacilli,1ZB3M@1386|Bacillus 91061|Bacilli I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA accD - 2.1.3.15,6.4.1.2 ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans k141_29033_1 1279009.ADICEAN_00250 4.22e-09 68.2 COG3291@1|root,COG4099@1|root,COG4935@1|root,COG3291@2|Bacteria,COG4099@2|Bacteria,COG4935@2|Bacteria,4NFU4@976|Bacteroidetes,47KEJ@768503|Cytophagia 976|Bacteroidetes G Parallel beta-helix repeats - - - - - - - - - - - - Beta_helix k141_19588_1 1453501.JELR01000001_gene1941 0.0 969.0 COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,1RMAP@1236|Gammaproteobacteria,464XP@72275|Alteromonadaceae 1236|Gammaproteobacteria M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamA GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - ko:K07277 - - - - ko00000,ko02000,ko03029 1.B.33 - - Bac_surface_Ag,POTRA k141_19588_2 1279017.AQYJ01000026_gene337 4.57e-174 497.0 COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,1RMIX@1236|Gammaproteobacteria,46453@72275|Alteromonadaceae 1236|Gammaproteobacteria M zinc metalloprotease rseP GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016021,GO:0016787,GO:0019219,GO:0019222,GO:0019538,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0043170,GO:0043856,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0045152,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:0140110,GO:1901564,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - ko:K11749 ko02024,ko04112,map02024,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - PDZ,PDZ_2,Peptidase_M50 k141_33836_1 218284.CCDN010000001_gene683 7.98e-138 397.0 COG0482@1|root,COG0482@2|Bacteria,1TPIZ@1239|Firmicutes,4HBJ6@91061|Bacilli,1ZBWQ@1386|Bacillus 91061|Bacilli J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 mnmA GO:0002097,GO:0002098,GO:0002143,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 2.8.1.13 ko:K00566 ko04122,map04122 - R08700 RC02313,RC02315 ko00000,ko00001,ko01000,ko03016 - - - tRNA_Me_trans k141_2860_2 1279017.AQYJ01000027_gene1720 2.92e-110 348.0 28HMG@1|root,2Z7W1@2|Bacteria,1NPZ0@1224|Proteobacteria,1SH34@1236|Gammaproteobacteria,46C4A@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_2860_3 1279017.AQYJ01000027_gene1721 7.74e-68 211.0 COG3040@1|root,COG3040@2|Bacteria,1RDAI@1224|Proteobacteria,1S3PW@1236|Gammaproteobacteria,466RV@72275|Alteromonadaceae 1236|Gammaproteobacteria M lipocalin blc GO:0005575,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0033554,GO:0044462,GO:0044464,GO:0050896,GO:0051716,GO:0071944 - ko:K03098 - - - - ko00000,ko04147 - - - Lipocalin_2 k141_29042_1 314285.KT71_16676 2.28e-53 183.0 COG0624@1|root,COG0624@2|Bacteria,1MWJS@1224|Proteobacteria,1RZXV@1236|Gammaproteobacteria,1J9BX@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase - - - - - - - - - - - - M20_dimer,Peptidase_M20,Peptidase_M28 k141_25642_1 666686.B1NLA3E_19880 3.42e-38 135.0 2BAQR@1|root,3245N@2|Bacteria,1UAF0@1239|Firmicutes,4IKTA@91061|Bacilli,1ZHGV@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_36103_1 218284.CCDN010000001_gene524 2.96e-180 516.0 COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HB1B@91061|Bacilli,1ZC0T@1386|Bacillus 91061|Bacilli T Signal transduction histidine kinase phoR - 2.7.13.3 ko:K07636 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_9,sCache_like k141_1652_1 1279017.AQYJ01000024_gene1189 2.84e-59 184.0 COG3232@1|root,COG3232@2|Bacteria,1N7P5@1224|Proteobacteria,1S5D7@1236|Gammaproteobacteria,46992@72275|Alteromonadaceae 1236|Gammaproteobacteria E 5-carboxymethyl-2-hydroxymuconate isomerase - - 5.3.3.10 ko:K01826 ko00350,ko01120,ko01220,map00350,map01120,map01220 M00533 R04379,R04482 RC01141,RC01162 ko00000,ko00001,ko00002,ko01000 - - - CHMI k141_5399_1 218284.CCDN010000005_gene3416 1.32e-105 313.0 COG1052@1|root,COG1052@2|Bacteria,1TPCX@1239|Firmicutes,4HASY@91061|Bacilli,1ZB0I@1386|Bacillus 91061|Bacilli CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family gyaR - 1.1.1.26 ko:K00015 ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120 - R00717,R01388 RC00031,RC00042 ko00000,ko00001,ko01000 - - - 2-Hacid_dh,2-Hacid_dh_C k141_24275_1 218284.CCDN010000001_gene5 6.89e-216 602.0 COG1206@1|root,COG1206@2|Bacteria,1TP67@1239|Firmicutes,4HB27@91061|Bacilli,1ZAR2@1386|Bacillus 91061|Bacilli J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs trmFO GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 ko:K04094 - - - - ko00000,ko01000,ko03016,ko03036 - - - GIDA k141_3016_1 338963.Pcar_0359 2.39e-81 265.0 COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,42M9S@68525|delta/epsilon subdivisions,2WJSZ@28221|Deltaproteobacteria,43S73@69541|Desulfuromonadales 28221|Deltaproteobacteria O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE clpB - - ko:K03695 ko04213,map04213 - - - ko00000,ko00001,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N k141_27897_1 326442.PSHAa1856 4.29e-294 817.0 COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,1RNB7@1236|Gammaproteobacteria,2Q07D@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria S metal-dependent hydrolase with the TIM-barrel fold - - - - - - - - - - - - Amidohydro_3 k141_27897_2 1279017.AQYJ01000029_gene3396 1.62e-59 189.0 2CHH4@1|root,32SC0@2|Bacteria,1NPE4@1224|Proteobacteria 1224|Proteobacteria S Bacterial PH domain - - - - - - - - - - - - bPH_5 k141_27897_3 1397527.Q670_03985 3.43e-59 186.0 COG5331@1|root,COG5331@2|Bacteria,1N0MD@1224|Proteobacteria,1SACM@1236|Gammaproteobacteria 1236|Gammaproteobacteria S MAPEG family - - - - - - - - - - - - MAPEG k141_27897_4 1279017.AQYJ01000029_gene3397 1.06e-152 436.0 COG4667@1|root,COG4667@2|Bacteria,1PV7M@1224|Proteobacteria,1RRPR@1236|Gammaproteobacteria,464M0@72275|Alteromonadaceae 1236|Gammaproteobacteria S esterase of the alpha-beta hydrolase superfamily - - - - - - - - - - - - Patatin k141_27897_5 1279017.AQYJ01000026_gene248 7.19e-82 247.0 COG3310@1|root,COG3310@2|Bacteria,1RDE0@1224|Proteobacteria,1S3X6@1236|Gammaproteobacteria,467Z8@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria - - - ko:K09941 - - - - ko00000 - - - DUF1415 k141_27897_6 1279017.AQYJ01000026_gene247 3.08e-63 199.0 COG3122@1|root,COG3122@2|Bacteria,1N15V@1224|Proteobacteria,1S5V0@1236|Gammaproteobacteria,467D6@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria yaiL GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K09912 - - - - ko00000 - - iECW_1372.ECW_m0432,iWFL_1372.ECW_m0432 DUF2058 k141_27897_8 1116369.KB890024_gene662 1.03e-89 281.0 COG0657@1|root,COG0657@2|Bacteria,1N3TH@1224|Proteobacteria,2U6EC@28211|Alphaproteobacteria 28211|Alphaproteobacteria I Carboxylesterase family - - - - - - - - - - - - Abhydrolase_3 k141_27897_10 1042377.AFPJ01000036_gene1232 7.68e-236 657.0 COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,1RQRP@1236|Gammaproteobacteria,46618@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Amidohydrolase family - - - - - - - - - - - - Amidohydro_1 k141_27897_11 666685.R2APBS1_1421 2.48e-28 112.0 COG2312@1|root,COG2312@2|Bacteria,1MU2S@1224|Proteobacteria,1RNDR@1236|Gammaproteobacteria,1X4PA@135614|Xanthomonadales 135614|Xanthomonadales O Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins - - - - - - - - - - - - Erythro_esteras,PCMT k141_34041_2 218284.CCDN010000010_gene4365 1.7e-139 395.0 COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,4HB01@91061|Bacilli,1ZBG9@1386|Bacillus 91061|Bacilli J Forms part of the polypeptide exit tunnel rplD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02926 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L4 k141_14044_1 192952.MM_2435 1.27e-23 104.0 arCOG02350@1|root,arCOG04001@1|root,arCOG02350@2157|Archaea,arCOG04001@2157|Archaea,2Y7NP@28890|Euryarchaeota,2NACQ@224756|Methanomicrobia 224756|Methanomicrobia T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA_2,PAS_9 k141_7794_1 1116375.VEJY3_17991 1.45e-158 451.0 COG0697@1|root,COG0697@2|Bacteria,1MWNF@1224|Proteobacteria,1S2ZJ@1236|Gammaproteobacteria,1XVSE@135623|Vibrionales 135623|Vibrionales EG of the drug metabolite transporter (DMT) superfamily - - - - - - - - - - - - EamA k141_7794_2 1198452.Jab_1c24210 2.59e-83 288.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,472C3@75682|Oxalobacteraceae 28216|Betaproteobacteria T Putative diguanylate phosphodiesterase - - - - - - - - - - - - EAL,GAF_2,GGDEF,HAMP,PAS,PAS_3,PAS_9,Response_reg k141_16163_1 1116375.VEJY3_18296 3.51e-117 355.0 COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,1RNKA@1236|Gammaproteobacteria 1236|Gammaproteobacteria H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses nadE - 6.3.1.5,6.3.5.1 ko:K01916,ko:K01950 ko00760,ko01100,map00760,map01100 M00115 R00189,R00257 RC00010,RC00100 ko00000,ko00001,ko00002,ko01000 - - - CN_hydrolase,NAD_synthase k141_14920_2 1279017.AQYJ01000025_gene717 6.03e-127 365.0 COG2197@1|root,COG2197@2|Bacteria,1NQH7@1224|Proteobacteria,1RNXI@1236|Gammaproteobacteria,46CIA@72275|Alteromonadaceae 1236|Gammaproteobacteria T helix_turn_helix, Lux Regulon - - - ko:K02479,ko:K07684 ko02020,map02020 M00471 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg k141_4282_2 643867.Ftrac_3242 9.04e-29 114.0 COG4874@1|root,COG4874@2|Bacteria,4NFG3@976|Bacteroidetes,47KEY@768503|Cytophagia 976|Bacteroidetes S Amidinotransferase - - - - - - - - - - - - Amidinotransf k141_9149_3 1279017.AQYJ01000020_gene1358 2.71e-52 175.0 COG4757@1|root,COG4757@2|Bacteria,1N2VM@1224|Proteobacteria,1SZX6@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Alpha/beta hydrolase family - - - - - - - - - - - - Hydrolase_4 k141_5634_1 272134.KB731324_gene3514 4.22e-89 275.0 28JRE@1|root,2Z9H3@2|Bacteria,1GBKI@1117|Cyanobacteria 1117|Cyanobacteria - - - - - - - - - - - - - - - k141_32710_1 1294265.JCM21738_2087 1.83e-65 204.0 COG2345@1|root,COG2345@2|Bacteria,1UYQM@1239|Firmicutes,4HAZZ@91061|Bacilli,1ZC2X@1386|Bacillus 91061|Bacilli K Helix-turn-helix domain - - - - - - - - - - - - ATC_hydrolase,HTH_20 k141_3017_1 1279017.AQYJ01000029_gene3326 7.54e-38 135.0 COG3823@1|root,COG3823@2|Bacteria,1R9YU@1224|Proteobacteria,1RZ5N@1236|Gammaproteobacteria,4679T@72275|Alteromonadaceae 1236|Gammaproteobacteria O Glutamine cyclotransferase - - 2.3.2.5 ko:K00683 - - - - ko00000,ko01000 - - - Glu_cyclase_2 k141_34042_1 698769.JFBD01000036_gene1493 1.95e-39 145.0 COG1164@1|root,COG1164@2|Bacteria,1TP4P@1239|Firmicutes,4HA7X@91061|Bacilli,4C4RC@84406|Virgibacillus 91061|Bacilli E Oligopeptidase F pepF GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - ko:K08602 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M3,Peptidase_M3_N k141_30273_1 42565.FP66_14735 3.81e-44 145.0 COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,1RMGV@1236|Gammaproteobacteria,1XHA1@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan dapF - 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 - - - DAP_epimerase k141_30273_2 42565.FP66_14740 2.34e-100 301.0 COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,1RMI2@1236|Gammaproteobacteria,1XHK6@135619|Oceanospirillales 135619|Oceanospirillales E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine lysA - 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N,Orn_DAP_Arg_deC k141_14921_1 1274524.BSONL12_11841 8.78e-72 235.0 COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,1TPKU@1239|Firmicutes,4H9KR@91061|Bacilli,1ZAVB@1386|Bacillus 91061|Bacilli GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type) fruA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563 2.7.1.202 ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1 - - PTS_EIIA_2,PTS_EIIC,PTS_IIB k141_27898_1 1132442.KB889752_gene229 1.93e-38 137.0 COG0564@1|root,COG0564@2|Bacteria,1TS1T@1239|Firmicutes,4HBRY@91061|Bacilli,1ZB25@1386|Bacillus 91061|Bacilli J Responsible for synthesis of pseudouridine from uracil rluD GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23,5.4.99.28,5.4.99.29 ko:K06177,ko:K06180 - - - - ko00000,ko01000,ko03009,ko03016 - - - PseudoU_synth_2 k141_27898_2 574375.BAGA_21175 5.41e-29 110.0 COG0639@1|root,COG0639@2|Bacteria,1TPCI@1239|Firmicutes,4HBD8@91061|Bacilli,1ZBK8@1386|Bacillus 91061|Bacilli T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP prpE GO:0003674,GO:0003824,GO:0004721,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008138,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 3.1.3.16,3.6.1.41 ko:K01090,ko:K01525 ko00230,map00230 - R00125 RC00002 ko00000,ko00001,ko01000 - - - Metallophos k141_5635_1 1453501.JELR01000001_gene2021 1.17e-126 369.0 COG0520@1|root,COG0520@2|Bacteria,1PJFE@1224|Proteobacteria,1RRJK@1236|Gammaproteobacteria,465WY@72275|Alteromonadaceae 1236|Gammaproteobacteria E Selenocysteine lyase - - - - - - - - - - - - Aminotran_5 k141_1812_2 1453501.JELR01000002_gene1051 1.85e-63 197.0 COG3602@1|root,COG3602@2|Bacteria 2|Bacteria S ACT domain - - 3.1.26.4 ko:K03469,ko:K09964 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - ACT_3,ACT_7 k141_19801_1 622637.KE124774_gene936 1.33e-53 180.0 COG0320@1|root,COG0320@2|Bacteria,1MVRD@1224|Proteobacteria,2TRP3@28211|Alphaproteobacteria,36XIV@31993|Methylocystaceae 28211|Alphaproteobacteria H Elongator protein 3, MiaB family, Radical SAM lipA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 ko:K03644 ko00785,ko01100,map00785,map01100 - R07767,R07768 RC01978 ko00000,ko00001,ko01000 - - - LIAS_N,Radical_SAM k141_16178_1 1042377.AFPJ01000032_gene2721 2.59e-187 526.0 COG0126@1|root,COG0126@2|Bacteria,1MUNU@1224|Proteobacteria,1RMUQ@1236|Gammaproteobacteria,464NK@72275|Alteromonadaceae 1236|Gammaproteobacteria G Belongs to the phosphoglycerate kinase family pgk GO:0003674,GO:0003824,GO:0004618,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.2.3 ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01512 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000,ko04147 - - iSbBS512_1146.SbBS512_E3351 PGK k141_19802_1 797114.C475_08211 1.95e-09 58.2 COG0323@1|root,arCOG01166@2157|Archaea,2XTK1@28890|Euryarchaeota,23T13@183963|Halobacteria 183963|Halobacteria L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex mutL - - ko:K03572 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - DNA_mis_repair,HATPase_c_3,MutL_C k141_32733_1 218284.CCDN010000001_gene24 3.99e-48 171.0 COG1196@1|root,COG1196@2|Bacteria,1TPJV@1239|Firmicutes,4HB89@91061|Bacilli,1ZAWM@1386|Bacillus 91061|Bacilli D Required for chromosome condensation and partitioning smc GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K03529 - - - - ko00000,ko03036 - - - SMC_N,SMC_hinge k141_14073_1 218284.CCDN010000001_gene1254 2.97e-104 306.0 COG1968@1|root,COG1968@2|Bacteria,1TPFA@1239|Firmicutes,4HCE7@91061|Bacilli,1ZC3Z@1386|Bacillus 91061|Bacilli V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin uppP - 3.6.1.27 ko:K06153 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - BacA k141_27175_2 1116375.VEJY3_12925 0.0 1405.0 COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,1RR1B@1236|Gammaproteobacteria,1XTYU@135623|Vibrionales 135623|Vibrionales L ATP-dependent RNA helicase hrpB - 3.6.4.13 ko:K03579 - - - - ko00000,ko01000 - - - DEAD,HA2,Helicase_C,HrpB_C k141_27175_3 1219076.N646_1594 0.0 926.0 COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,1RNHV@1236|Gammaproteobacteria,1XVGW@135623|Vibrionales 135623|Vibrionales M Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) mrcB GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.4.1.129,3.4.16.4 ko:K05365 ko00550,map00550 - R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase,UB2H k141_868_1 218284.CCDN010000008_gene4263 6.15e-199 563.0 COG4477@1|root,COG4477@2|Bacteria,1TQR7@1239|Firmicutes,4HA15@91061|Bacilli,1ZAWX@1386|Bacillus 91061|Bacilli D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization ezrA GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000918,GO:0000921,GO:0005575,GO:0005623,GO:0005886,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0022402,GO:0022607,GO:0031106,GO:0032185,GO:0032506,GO:0034622,GO:0043933,GO:0044085,GO:0044464,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051301,GO:0051302,GO:0051781,GO:0061640,GO:0065003,GO:0065007,GO:0070925,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 - ko:K06286 - - - - ko00000,ko03036 - - - EzrA k141_868_2 218284.CCDN010000008_gene4264 2.35e-42 149.0 COG1114@1|root,COG1114@2|Bacteria,1TQIS@1239|Firmicutes,4HAKA@91061|Bacilli,1ZAST@1386|Bacillus 91061|Bacilli E Component of the transport system for branched-chain amino acids braB GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015175,GO:0015179,GO:0015188,GO:0015190,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0034220,GO:0042221,GO:0042493,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903785,GO:1903825,GO:1905039 - ko:K03311 - - - - ko00000 2.A.26 - - Branch_AA_trans k141_18762_1 1453501.JELR01000002_gene572 2.97e-113 335.0 2BXSN@1|root,32R1X@2|Bacteria,1MYVK@1224|Proteobacteria,1S821@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF4243) - - - - - - - - - - - - DUF4243 k141_18762_2 589873.EP13_05530 2.1e-181 542.0 COG1629@1|root,COG4771@2|Bacteria,1MW4X@1224|Proteobacteria,1RPVY@1236|Gammaproteobacteria,465N5@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - CarboxypepD_reg,Plug,TonB_dep_Rec k141_37470_1 1453501.JELR01000002_gene772 6.33e-82 266.0 COG0834@1|root,COG4623@1|root,COG0834@2|Bacteria,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,1RM8W@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella - GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - ko:K18691 - - - - ko00000,ko01000,ko01011 - - - SBP_bac_3,SLT k141_3031_1 218284.CCDN010000006_gene3609 8.61e-151 445.0 COG0557@1|root,COG0557@2|Bacteria,1TQ1G@1239|Firmicutes,4HBBH@91061|Bacilli,1ZBDP@1386|Bacillus 91061|Bacilli K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs rnr - - ko:K12573 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03016,ko03019 - - - OB_RNB,RNB,S1 k141_23482_1 1453501.JELR01000001_gene3017 2.13e-105 310.0 COG3063@1|root,COG3063@2|Bacteria,1RAFJ@1224|Proteobacteria,1S5H6@1236|Gammaproteobacteria,467DR@72275|Alteromonadaceae 1236|Gammaproteobacteria NU COG3063 Tfp pilus assembly protein PilF pilF - - ko:K02656 - - - - ko00000,ko02035,ko02044 - - - TPR_12,TPR_16,TPR_19,TPR_2,TPR_8 k141_12822_2 1279017.AQYJ01000025_gene472 8.16e-32 113.0 2DCC8@1|root,2ZDND@2|Bacteria 2|Bacteria S Hydrogenase/urease nickel incorporation, metallochaperone, hypA - - - - - - - - - - - - HypA k141_12822_3 338966.Ppro_2780 3.5e-06 48.1 COG0068@1|root,COG0068@2|Bacteria,1MVP8@1224|Proteobacteria,42M3G@68525|delta/epsilon subdivisions,2WJ51@28221|Deltaproteobacteria,43S2B@69541|Desulfuromonadales 28221|Deltaproteobacteria O Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide hypF - - ko:K04656 - - - - ko00000 - - iAF987.Gmet_0119 Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF k141_35308_2 218284.CCDN010000008_gene4263 3.7e-191 548.0 COG4477@1|root,COG4477@2|Bacteria,1TQR7@1239|Firmicutes,4HA15@91061|Bacilli,1ZAWX@1386|Bacillus 91061|Bacilli D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization ezrA GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000918,GO:0000921,GO:0005575,GO:0005623,GO:0005886,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0022402,GO:0022607,GO:0031106,GO:0032185,GO:0032506,GO:0034622,GO:0043933,GO:0044085,GO:0044464,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051301,GO:0051302,GO:0051781,GO:0061640,GO:0065003,GO:0065007,GO:0070925,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 - ko:K06286 - - - - ko00000,ko03036 - - - EzrA k141_14074_1 218284.CCDN010000002_gene2852 1.27e-92 280.0 COG2603@1|root,COG2603@2|Bacteria,1TQ8T@1239|Firmicutes,4HBX4@91061|Bacilli,1ZCJF@1386|Bacillus 91061|Bacilli S tRNA 2-selenouridine synthase selU - - ko:K06917 - - - - ko00000,ko01000,ko03016 - - - Rhodanese k141_24561_2 1385511.N783_03050 6.94e-27 107.0 COG1028@1|root,COG1028@2|Bacteria,1TPZ8@1239|Firmicutes,4HAMW@91061|Bacilli,2Y8YM@289201|Pontibacillus 91061|Bacilli IQ 2-deoxy-D-gluconate 3-dehydrogenase - - - - - - - - - - - - adh_short_C2 k141_11594_3 218284.CCDN010000008_gene4207 3.18e-80 252.0 COG3104@1|root,COG3104@2|Bacteria,1TP81@1239|Firmicutes,4HAF2@91061|Bacilli,1ZAVZ@1386|Bacillus 91061|Bacilli E amino acid peptide transporter dtpT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03305 - - - - ko00000 2.A.17 - - PTR2 k141_29242_1 1121382.JQKG01000026_gene2933 1.17e-12 71.6 COG0791@1|root,COG1388@1|root,COG0791@2|Bacteria,COG1388@2|Bacteria,1WJI4@1297|Deinococcus-Thermus 2|Bacteria M Cell wall-associated hydrolase (invasion-associated protein) mltD - - ko:K03791,ko:K08307,ko:K12204,ko:K19223 - - - - ko00000,ko01000,ko01002,ko01011,ko02044 3.A.7.10.1,3.A.7.9.1 CBM50,GH19 - LysM,NLPC_P60,SLT,T4SS_TraI k141_31435_1 218284.CCDN010000001_gene1570 2.96e-18 83.6 COG1960@1|root,COG1960@2|Bacteria,1TQC8@1239|Firmicutes,4HC6Y@91061|Bacilli,1ZCXT@1386|Bacillus 91061|Bacilli I Acyl-CoA dehydrogenase, middle domain - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M k141_31435_2 218284.CCDN010000001_gene1571 6.23e-68 220.0 COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HACS@91061|Bacilli,1ZATG@1386|Bacillus 91061|Bacilli IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - 6.2.1.3,6.2.1.34 ko:K01897,ko:K12508 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding,AMP-binding_C k141_31435_3 218284.CCDN010000001_gene1571 5.91e-05 44.7 COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HACS@91061|Bacilli,1ZATG@1386|Bacillus 91061|Bacilli IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - 6.2.1.3,6.2.1.34 ko:K01897,ko:K12508 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding,AMP-binding_C k141_9181_2 1042377.AFPJ01000037_gene2986 0.0 959.0 COG0366@1|root,COG0366@2|Bacteria,1MVKX@1224|Proteobacteria,1RMXP@1236|Gammaproteobacteria,4642X@72275|Alteromonadaceae 1236|Gammaproteobacteria G Alpha amylase ycjM - 2.4.1.7 ko:K00690 ko00500,map00500 - R00803 RC00028 ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,DUF3459,Malt_amylase_C k141_9181_3 1279017.AQYJ01000021_gene2905 2.28e-17 81.3 COG0477@1|root,COG2814@2|Bacteria,1RAYJ@1224|Proteobacteria,1S7XJ@1236|Gammaproteobacteria,46AYE@72275|Alteromonadaceae 1236|Gammaproteobacteria EGP Transmembrane secretion effector - - - - - - - - - - - - MFS_1,MFS_3 k141_27176_1 218284.CCDN010000001_gene1874 7.13e-106 312.0 COG0329@1|root,COG0329@2|Bacteria,1TPCK@1239|Firmicutes,4H9K9@91061|Bacilli,1ZBNR@1386|Bacillus 91061|Bacilli E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) dapA - 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS k141_34058_1 42565.FP66_14200 3.52e-109 324.0 COG2208@1|root,COG3707@1|root,COG2208@2|Bacteria,COG3707@2|Bacteria,1QU7V@1224|Proteobacteria,1T1QA@1236|Gammaproteobacteria,1XHV9@135619|Oceanospirillales 135619|Oceanospirillales KT Sigma factor PP2C-like phosphatases - - - - - - - - - - - - SpoIIE k141_34058_2 42565.FP66_14195 2.85e-147 417.0 COG2853@1|root,COG2853@2|Bacteria,1MVX0@1224|Proteobacteria,1RNPS@1236|Gammaproteobacteria,1XJNB@135619|Oceanospirillales 135619|Oceanospirillales M (Lipo)protein vacJ - - ko:K04754 - - - - ko00000 - - - MlaA k141_17337_1 1156935.QWE_23326 4.61e-67 214.0 COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,2TRIG@28211|Alphaproteobacteria,4BFVM@82115|Rhizobiaceae 28211|Alphaproteobacteria K transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_869_2 218284.CCDN010000007_gene3892 1.29e-64 197.0 COG4357@1|root,COG4357@2|Bacteria,1VB64@1239|Firmicutes,4HMGX@91061|Bacilli,1ZIGE@1386|Bacillus 91061|Bacilli S CHY zinc finger - - - - - - - - - - - - zf-CHY k141_29243_1 1121945.ATXS01000007_gene462 3.31e-16 78.6 COG1171@1|root,arCOG01431@2157|Archaea,2XT4W@28890|Euryarchaeota,23SNZ@183963|Halobacteria 183963|Halobacteria E Threonine dehydratase ilvA1 - 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - - ACT_4,PALP k141_29243_2 1287116.X734_10270 1.29e-34 130.0 COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,2TUMJ@28211|Alphaproteobacteria,43NWD@69277|Phyllobacteriaceae 28211|Alphaproteobacteria E Aminotransferase class-V - - - - - - - - - - - - Aminotran_5 k141_18764_1 218284.CCDN010000001_gene1926 3.15e-87 270.0 COG3144@1|root,COG3144@2|Bacteria,1VI6B@1239|Firmicutes,4HGUR@91061|Bacilli,1ZJ6D@1386|Bacillus 91061|Bacilli N Flagellar hook-length control fliK GO:0001539,GO:0006928,GO:0008150,GO:0009987,GO:0040011,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588 - ko:K02414 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_hook k141_19803_1 1279017.AQYJ01000029_gene3348 1.57e-95 288.0 COG4446@1|root,COG4446@2|Bacteria,1N31A@1224|Proteobacteria,1RRKY@1236|Gammaproteobacteria,466QZ@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF1499) - - - - - - - - - - - - DUF1499 k141_3032_1 1294265.JCM21738_4519 3.81e-94 298.0 COG2200@1|root,COG3300@1|root,COG2200@2|Bacteria,COG3300@2|Bacteria,1TS8B@1239|Firmicutes,4ISKA@91061|Bacilli,1ZDC3@1386|Bacillus 91061|Bacilli T Bacterial signalling protein N terminal repeat - - 2.7.7.65 ko:K21023 ko02025,map02025 - - - ko00000,ko00001,ko01000 - - - EAL,GAF,GGDEF,MASE3,MHYT,PAS_4,PAS_9 k141_22147_1 935837.JAEK01000006_gene4242 1.78e-89 278.0 COG1621@1|root,COG1621@2|Bacteria,1TPAE@1239|Firmicutes,4H9Y7@91061|Bacilli,1ZCBA@1386|Bacillus 91061|Bacilli G invertase sacA - 3.2.1.26 ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00801,R00802,R02410,R03635,R03921,R06088 RC00028,RC00077 ko00000,ko00001,ko01000 - GH32 iYO844.BSU38040 Glyco_hydro_32C,Glyco_hydro_32N k141_36248_1 394221.Mmar10_2649 8.26e-216 619.0 COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,2TSGE@28211|Alphaproteobacteria,43WYB@69657|Hyphomonadaceae 28211|Alphaproteobacteria S COG0457 FOG TPR repeat - - - - - - - - - - - - Sulfotransfer_3,TPR_16,TPR_19,TPR_2,TPR_8 k141_14076_2 218284.CCDN010000001_gene745 8.08e-13 68.6 29RH9@1|root,30CK6@2|Bacteria,1UA17@1239|Firmicutes,4IK9T@91061|Bacilli,1ZG2T@1386|Bacillus 91061|Bacilli - - yqfB - - - - - - - - - - - - k141_7819_1 1279017.AQYJ01000019_gene1500 1.89e-56 191.0 COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,1RMXX@1236|Gammaproteobacteria,4663F@72275|Alteromonadaceae 1236|Gammaproteobacteria S Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane murJ GO:0000270,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0006869,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0010876,GO:0015647,GO:0015648,GO:0015835,GO:0015836,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0030203,GO:0031224,GO:0031226,GO:0033036,GO:0034203,GO:0034204,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0046836,GO:0051179,GO:0051234,GO:0055085,GO:0061024,GO:0065007,GO:0065008,GO:0070589,GO:0071554,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0071944,GO:0097035,GO:1901135,GO:1901137,GO:1901264,GO:1901505,GO:1901564,GO:1901566,GO:1901576 - ko:K03980 - - - - ko00000,ko01011,ko02000 2.A.66.4 - iECO103_1326.ECO103_1114 MVIN k141_24562_1 1219076.N646_0706 8.74e-105 318.0 COG0494@1|root,COG0671@1|root,COG0494@2|Bacteria,COG0671@2|Bacteria,1NCFS@1224|Proteobacteria,1SCXM@1236|Gammaproteobacteria,1XTRI@135623|Vibrionales 135623|Vibrionales IL COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - - - - - - - - - - NUDIX,PAP2 k141_29244_1 218284.CCDN010000001_gene590 1.41e-101 305.0 COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,4H9Q8@91061|Bacilli,1ZBRE@1386|Bacillus 91061|Bacilli D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase tig GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K03545 - - - - ko00000 - - - FKBP_C,Trigger_C,Trigger_N k141_23483_2 1279017.AQYJ01000018_gene778 1.69e-67 209.0 COG2137@1|root,COG2137@2|Bacteria,1N6P6@1224|Proteobacteria,1SCMF@1236|Gammaproteobacteria,468BK@72275|Alteromonadaceae 1236|Gammaproteobacteria S Modulates RecA activity recX GO:0003674,GO:0005488,GO:0005515,GO:0006282,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0019219,GO:0019222,GO:0019899,GO:0030234,GO:0031323,GO:0031668,GO:0033554,GO:0043086,GO:0044092,GO:0048583,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0071496,GO:0080090,GO:0080134,GO:0080135,GO:0098772,GO:2001020 - ko:K03565 - - - - ko00000,ko03400 - - - RecX k141_23483_3 66373.JOFQ01000035_gene2810 5.18e-33 127.0 COG0554@1|root,COG0554@2|Bacteria,2GM13@201174|Actinobacteria 201174|Actinobacteria C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate glpK GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 - R00847 RC00002,RC00017 ko00000,ko00001,ko01000,ko04147 - - - FGGY_C,FGGY_N k141_5651_2 1279017.AQYJ01000029_gene3741 1.44e-34 120.0 COG2168@1|root,COG2168@2|Bacteria,1NGF3@1224|Proteobacteria,1SGPI@1236|Gammaproteobacteria,468W2@72275|Alteromonadaceae 1236|Gammaproteobacteria P DsrH like protein tusB GO:0002097,GO:0002098,GO:0002143,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1902494,GO:1990228,GO:1990234 - ko:K07237 ko04122,map04122 - - - ko00000,ko00001,ko03016 - - - DsrH k141_5651_3 1453501.JELR01000001_gene2207 1.35e-27 102.0 COG2920@1|root,COG2920@2|Bacteria,1RGVG@1224|Proteobacteria,1S5ZA@1236|Gammaproteobacteria,467QI@72275|Alteromonadaceae 1236|Gammaproteobacteria P Part of a sulfur-relay system tusE GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097163,GO:0140104,GO:1901360 - ko:K11179 ko04122,map04122 - - - ko00000,ko00001,ko01000,ko03016 - - - DsrC k141_11596_2 218284.CCDN010000012_gene4439 5e-74 222.0 2CYE0@1|root,30CMF@2|Bacteria,1UA3B@1239|Firmicutes,4IKD0@91061|Bacilli,1ZGHE@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_7820_1 1234679.BN424_3318 3.88e-23 97.4 2B9XI@1|root,323AV@2|Bacteria,1V7VV@1239|Firmicutes,4HK2T@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF1071) - - - - - - - - - - - - DUF1071 k141_24563_2 218284.CCDN010000005_gene3263 2.02e-93 277.0 COG1073@1|root,COG1073@2|Bacteria,1TTC0@1239|Firmicutes,4HBCG@91061|Bacilli,1ZBIJ@1386|Bacillus 91061|Bacilli S COG1073 Hydrolases of the alpha beta superfamily yitV - - ko:K06889 - - - - ko00000 - - - Abhydrolase_1,Hydrolase_4,Peptidase_S9 k141_31436_1 1294265.JCM21738_1618 3.96e-11 62.4 COG3434@1|root,COG3434@2|Bacteria,1TPWC@1239|Firmicutes,4HD4Q@91061|Bacilli,1ZDNG@1386|Bacillus 91061|Bacilli T signal transduction protein containing EAL and modified HD-GYP domains yuxH - - - - - - - - - - - EAL,HDOD k141_31436_2 796606.BMMGA3_15620 1.43e-51 170.0 28N5J@1|root,2ZBAR@2|Bacteria,1V0YS@1239|Firmicutes,4HYNX@91061|Bacilli,1ZI7X@1386|Bacillus 91061|Bacilli S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains - - - - - - - - - - - - - k141_16179_1 1448857.JFAP01000004_gene704 3.4e-26 110.0 COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,42MFC@68525|delta/epsilon subdivisions,2YMN5@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family bioA - 2.6.1.62 ko:K00833 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R03231 RC00006,RC00887 ko00000,ko00001,ko00002,ko01000,ko01007 - - iIT341.HP0976 AAA_26,Aminotran_3 k141_16360_1 1453501.JELR01000002_gene1450 2.05e-76 231.0 COG1595@1|root,COG1595@2|Bacteria,1N2DR@1224|Proteobacteria,1S7D6@1236|Gammaproteobacteria,467MI@72275|Alteromonadaceae 1236|Gammaproteobacteria K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_7059_1 1340434.AXVA01000003_gene2283 2.33e-81 256.0 COG1524@1|root,COG1524@2|Bacteria,1UY6W@1239|Firmicutes,4HDR4@91061|Bacilli,1ZDAM@1386|Bacillus 91061|Bacilli S Type I phosphodiesterase / nucleotide pyrophosphatase - - - - - - - - - - - - Phosphodiest k141_35524_2 218284.CCDN010000001_gene1951 1.9e-20 84.0 2E6HR@1|root,33150@2|Bacteria,1VF6G@1239|Firmicutes,4IR8Y@91061|Bacilli,1ZKDM@1386|Bacillus 91061|Bacilli S YCII-related domain - - - - - - - - - - - - YCII k141_11828_2 866895.HBHAL_1566 1.87e-09 58.9 COG2866@1|root,COG2866@2|Bacteria,1V09S@1239|Firmicutes,4HBF2@91061|Bacilli,3NFXX@45667|Halobacillus 91061|Bacilli E Protein of unknown function (DUF2817) - - - - - - - - - - - - DUF2817 k141_24752_1 1331060.RLDS_18820 1.33e-22 102.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MV8W@1224|Proteobacteria,2TSUV@28211|Alphaproteobacteria,2JZV0@204457|Sphingomonadales 204457|Sphingomonadales P receptor - - - - - - - - - - - - Plug,TonB_dep_Rec k141_20025_1 357808.RoseRS_0542 5.74e-28 109.0 COG1028@1|root,COG1028@2|Bacteria,2G8K5@200795|Chloroflexi,3779V@32061|Chloroflexia 32061|Chloroflexia IQ PFAM short-chain dehydrogenase reductase SDR - - 1.5.1.33 ko:K03793 - - - - ko00000,ko01000 - - - adh_short_C2 k141_20025_2 1384066.JAGT01000001_gene1091 2.07e-14 72.4 COG0720@1|root,COG0720@2|Bacteria,1VAJX@1239|Firmicutes,24JS9@186801|Clostridia,3WJD8@541000|Ruminococcaceae 186801|Clostridia H 6-pyruvoyl tetrahydropterin synthase queD - 4.1.2.50,4.2.3.12 ko:K01737 ko00790,ko01100,map00790,map01100 M00842,M00843 R04286,R09959 RC01117,RC02846,RC02847 ko00000,ko00001,ko00002,ko01000,ko03016 - - - PTPS k141_5791_1 265729.GS18_0217385 3.07e-96 294.0 COG1823@1|root,COG1823@2|Bacteria,1UPUK@1239|Firmicutes,4HAJY@91061|Bacilli,1ZB7C@1386|Bacillus 91061|Bacilli U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family tcyP - - ko:K06956 - - - - ko00000 - - - SDF k141_22445_1 218284.CCDN010000007_gene3797 5.48e-06 47.0 COG0445@1|root,COG0445@2|Bacteria,1TQ4B@1239|Firmicutes,4HA6S@91061|Bacilli,1ZB67@1386|Bacillus 91061|Bacilli D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 gidA GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - ko:K03495 - - R08701 RC00053,RC00209,RC00870 ko00000,ko03016,ko03036 - - - GIDA,GIDA_assoc k141_22445_2 218284.CCDN010000007_gene3796 5.67e-162 464.0 COG0486@1|root,COG0486@2|Bacteria,1TPJF@1239|Firmicutes,4HA06@91061|Bacilli,1ZBTZ@1386|Bacillus 91061|Bacilli S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 mnmE - - ko:K03650 - - R08701 RC00053,RC00209,RC00870 ko00000,ko01000,ko03016 - - - MMR_HSR1,MnmE_helical,TrmE_N k141_30407_1 218284.CCDN010000007_gene3965 3.63e-112 338.0 COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,4H9VK@91061|Bacilli,1ZB07@1386|Bacillus 91061|Bacilli G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system - - 3.6.3.17 ko:K02056 - M00221 - - ko00000,ko00002,ko01000,ko02000 3.A.1.2 - - ABC_tran k141_1970_2 1116375.VEJY3_22111 1.76e-205 570.0 COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,1RMM4@1236|Gammaproteobacteria,1XSX7@135623|Vibrionales 135623|Vibrionales V ABC-type multidrug transport system, ATPase component - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_1970_3 223926.28808656 7.14e-181 508.0 COG0845@1|root,COG0845@2|Bacteria,1MUG6@1224|Proteobacteria,1RP16@1236|Gammaproteobacteria,1XSQ7@135623|Vibrionales 135623|Vibrionales M HlyD family secretion protein - - - ko:K01993 - - - - ko00000 - - - Biotin_lipoyl_2,HlyD_3 k141_1970_4 1116375.VEJY3_22101 3.68e-164 462.0 COG0384@1|root,COG0384@2|Bacteria,1R9X4@1224|Proteobacteria,1RZ0R@1236|Gammaproteobacteria,1XTKE@135623|Vibrionales 135623|Vibrionales S epimerase, PhzC PhzF homolog - - - - - - - - - - - - PhzC-PhzF k141_1970_5 223926.28808663 8.99e-59 184.0 COG0640@1|root,COG0640@2|Bacteria,1N7I7@1224|Proteobacteria,1SQPT@1236|Gammaproteobacteria,1XYC8@135623|Vibrionales 135623|Vibrionales K transcriptional regulators - - - - - - - - - - - - HTH_20,HTH_5 k141_24753_1 1453501.JELR01000006_gene14 1.14e-26 114.0 COG4223@1|root,COG4223@2|Bacteria,1N10X@1224|Proteobacteria,1RYCQ@1236|Gammaproteobacteria,46D2D@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF1631) - - - - - - - - - - - - DUF1631 k141_36418_2 1279017.AQYJ01000029_gene3748 6.89e-121 350.0 COG0398@1|root,COG0398@2|Bacteria,1MVF3@1224|Proteobacteria,1S5SK@1236|Gammaproteobacteria,468K2@72275|Alteromonadaceae 1236|Gammaproteobacteria S SNARE associated Golgi protein - - - - - - - - - - - - SNARE_assoc k141_36418_3 402881.Plav_2602 4.54e-65 210.0 2C5U9@1|root,2Z9NJ@2|Bacteria,1N9BC@1224|Proteobacteria 1224|Proteobacteria S Bacterial protein of unknown function (Gcw_chp) - - - - - - - - - - - - Gcw_chp k141_36418_4 1122135.KB893139_gene1333 8.33e-22 95.9 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria 28211|Alphaproteobacteria C belongs to the aldehyde dehydrogenase family betB - 1.2.1.8 ko:K00130 ko00260,ko01100,map00260,map01100 M00555 R02565,R02566 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_7061_1 1453501.JELR01000002_gene1010 5.99e-156 461.0 COG4773@1|root,COG4773@2|Bacteria,1Q323@1224|Proteobacteria,1RSQ6@1236|Gammaproteobacteria,46DEK@72275|Alteromonadaceae 1236|Gammaproteobacteria P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec k141_20026_1 218284.CCDN010000002_gene2216 4e-192 539.0 COG2309@1|root,COG2309@2|Bacteria,1TP65@1239|Firmicutes,4H9W8@91061|Bacilli,1ZCU3@1386|Bacillus 91061|Bacilli E COG2309 Leucyl aminopeptidase (aminopeptidase T) ampS - - ko:K19689 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M29 k141_31564_1 218284.CCDN010000001_gene1751 4.2e-88 269.0 COG0626@1|root,COG0626@2|Bacteria,1TPC7@1239|Firmicutes,4HAFQ@91061|Bacilli,1ZAR9@1386|Bacillus 91061|Bacilli E cystathionine metC GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0016740,GO:0016765,GO:0016829,GO:0016846 4.4.1.8 ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU11880 Cys_Met_Meta_PP k141_31564_2 218284.CCDN010000001_gene1750 1.16e-32 124.0 COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,1TPYV@1239|Firmicutes,4HAB5@91061|Bacilli,1ZBGC@1386|Bacillus 91061|Bacilli E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine yitJ - 1.5.1.20,2.1.1.10 ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 M00377 R00650,R01224,R07168 RC00003,RC00035,RC00081 ko00000,ko00001,ko00002,ko01000 - - - MTHFR,S-methyl_trans k141_29432_2 1122917.KB899662_gene2154 9.21e-42 145.0 COG1794@1|root,COG1794@2|Bacteria,1TQ6M@1239|Firmicutes,4HR12@91061|Bacilli,26X1X@186822|Paenibacillaceae 91061|Bacilli M Asp/Glu/Hydantoin racemase racD - 5.1.1.13 ko:K01779 ko00250,ko01054,map00250,map01054 - R00491 RC00302 ko00000,ko00001,ko01000 - - - Asp_Glu_race k141_26070_1 1056820.KB900631_gene2384 3.3e-84 266.0 COG3425@1|root,COG3425@2|Bacteria,1MU4K@1224|Proteobacteria,1S16F@1236|Gammaproteobacteria,2PPKP@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria I Hydroxymethylglutaryl-coenzyme A synthase N terminal - - 2.3.3.10 ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 M00088,M00095 R01978 RC00004,RC00503 ko00000,ko00001,ko00002,ko01000,ko01008 - - - HMG_CoA_synt_C,HMG_CoA_synt_N k141_5792_1 218284.CCDN010000002_gene2585 6.08e-35 130.0 COG0457@1|root,COG0457@2|Bacteria,1V0WM@1239|Firmicutes,4HISB@91061|Bacilli,1ZHQF@1386|Bacillus 91061|Bacilli S Tetratricopeptide repeat - - - - - - - - - - - - - k141_5792_2 218284.CCDN010000002_gene2586 9.3e-70 224.0 COG0726@1|root,COG0726@2|Bacteria,1TYRH@1239|Firmicutes,4HEQR@91061|Bacilli,1ZEGM@1386|Bacillus 91061|Bacilli G deacetylase nodB1 - - - - - - - - - - - Cu_amine_oxidN1,Polysacc_deac_1 k141_32952_1 406124.ACPC01000047_gene1811 2.64e-28 120.0 COG1511@1|root,COG1511@2|Bacteria,1TRMJ@1239|Firmicutes,4HB2N@91061|Bacilli,1ZBC1@1386|Bacillus 91061|Bacilli S domain protein - - - - - - - - - - - - - k141_1972_1 28532.XP_010537163.1 3.79e-29 115.0 COG0442@1|root,KOG4163@2759|Eukaryota,37QBN@33090|Viridiplantae,3GFUW@35493|Streptophyta,3HRX2@3699|Brassicales 35493|Streptophyta J Prolyl-tRNA synthetase, C-terminal - GO:0000003,GO:0003006,GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009507,GO:0009532,GO:0009536,GO:0009553,GO:0009570,GO:0009791,GO:0009908,GO:0009987,GO:0010109,GO:0010154,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019222,GO:0019538,GO:0019752,GO:0022414,GO:0031323,GO:0032501,GO:0032502,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0035670,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0048229,GO:0048316,GO:0048367,GO:0048437,GO:0048438,GO:0048440,GO:0048467,GO:0048481,GO:0048608,GO:0048731,GO:0048827,GO:0048856,GO:0050789,GO:0050794,GO:0061458,GO:0065007,GO:0071704,GO:0090304,GO:0090567,GO:0099402,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,ProRS-C_1,tRNA-synt_2b k141_20994_1 1279017.AQYJ01000028_gene2280 4.5e-35 136.0 COG1501@1|root,COG1501@2|Bacteria,1MWNJ@1224|Proteobacteria,1RMJ9@1236|Gammaproteobacteria,465UA@72275|Alteromonadaceae 1236|Gammaproteobacteria G Belongs to the glycosyl hydrolase 31 family malZ GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016758,GO:0033825,GO:0046527 2.4.1.161,3.2.1.177,3.2.1.20 ko:K01187,ko:K01811,ko:K18820 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00028,R00801,R00802,R06087,R06088 RC00028,RC00049,RC00077 ko00000,ko00001,ko01000 - GH31 - CBM_20,DUF4968,DUF5110,Gal_mutarotas_2,Glyco_hydro_31,PA14 k141_10493_2 1280001.BAOA01000059_gene2279 9.66e-66 201.0 COG1314@1|root,COG1314@2|Bacteria,1N8MF@1224|Proteobacteria,1SD3P@1236|Gammaproteobacteria,1XXUA@135623|Vibrionales 135623|Vibrionales U Preprotein translocase subunit SecG secG - - ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecG k141_10493_3 1116375.VEJY3_12715 9.26e-305 833.0 COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,1RMR2@1236|Gammaproteobacteria,1XU1U@135623|Vibrionales 135623|Vibrionales G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate glmM - 5.4.2.10 ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 - R02060 RC00408 ko00000,ko00001,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV k141_10493_4 1116375.VEJY3_12720 3.36e-160 452.0 COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,1RM8G@1236|Gammaproteobacteria,1XTE1@135623|Vibrionales 135623|Vibrionales H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives folP - 2.5.1.15 ko:K00796 ko00790,ko01100,map00790,map01100 M00126,M00841 R03066,R03067 RC00121,RC00842 ko00000,ko00001,ko00002,ko01000 - - - Pterin_bind k141_10493_5 1116375.VEJY3_12725 0.0 1209.0 COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,1RME8@1236|Gammaproteobacteria,1XT56@135623|Vibrionales 135623|Vibrionales O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins ftsH - - ko:K03798 - M00742 - - ko00000,ko00002,ko01000,ko01002,ko03110 - - - AAA,FtsH_ext,Peptidase_M41 k141_10493_6 223926.28807462 3.71e-144 407.0 COG0293@1|root,COG0293@2|Bacteria,1MW1C@1224|Proteobacteria,1RN5M@1236|Gammaproteobacteria,1XTF8@135623|Vibrionales 135623|Vibrionales J Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit ftsJ - 2.1.1.166 ko:K02427 - - - - ko00000,ko01000,ko03009 - - - FtsJ k141_10493_7 55601.VANGNB10_cI0534c 4.24e-58 180.0 COG1534@1|root,COG1534@2|Bacteria,1N8K5@1224|Proteobacteria,1SDIM@1236|Gammaproteobacteria,1XXTH@135623|Vibrionales 135623|Vibrionales J RNA-binding protein containing KH domain, possibly ribosomal protein yhbY - - ko:K07574 - - - - ko00000,ko03009 - - - CRS1_YhbY k141_10493_8 1280001.BAOA01000059_gene2285 1.05e-95 280.0 COG0782@1|root,COG0782@2|Bacteria,1RCXW@1224|Proteobacteria,1S3UP@1236|Gammaproteobacteria,1XTS8@135623|Vibrionales 135623|Vibrionales K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides greA GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - ko:K03624 - - - - ko00000,ko03021 - - - GreA_GreB,GreA_GreB_N k141_10493_9 223926.28807465 2.54e-159 454.0 COG3203@1|root,COG3203@2|Bacteria,1QTID@1224|Proteobacteria,1SWVI@1236|Gammaproteobacteria,1XSFV@135623|Vibrionales 135623|Vibrionales M COG3203 Outer membrane protein (porin) ompU GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - ko:K08720 ko01501,ko05111,map01501,map05111 - - - ko00000,ko00001,ko02000 1.B.1.2.1 - - Porin_1,Porin_4 k141_10493_10 1116375.VEJY3_12750 5.8e-147 425.0 COG2027@1|root,COG2027@2|Bacteria,1MW40@1224|Proteobacteria,1RP8V@1236|Gammaproteobacteria,1XUAV@135623|Vibrionales 135623|Vibrionales M COG2027 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) dacB - 3.4.16.4 ko:K07259 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - Peptidase_S13 k141_37659_1 85643.Tmz1t_3904 3.62e-79 250.0 COG0438@1|root,COG0438@2|Bacteria,1R01U@1224|Proteobacteria 1224|Proteobacteria M glycosyl transferase group 1 - - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4 k141_34258_2 351348.Maqu_2250 1.53e-64 205.0 COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,1RS6U@1236|Gammaproteobacteria,4648K@72275|Alteromonadaceae 1236|Gammaproteobacteria K Transcriptional regulator IV02_27905 - - - - - - - - - - - HTH_1,LysR_substrate k141_3264_2 218284.CCDN010000001_gene4 2.3e-162 460.0 COG4974@1|root,COG4974@2|Bacteria,1TPQB@1239|Firmicutes,4HARA@91061|Bacilli,1ZB91@1386|Bacillus 91061|Bacilli L tyrosine recombinase XerC xerC - - ko:K03733,ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase k141_11843_1 1307436.PBF_14774 1.17e-86 257.0 COG3449@1|root,COG3449@2|Bacteria,1V3RQ@1239|Firmicutes,4IPKI@91061|Bacilli,1ZFWU@1386|Bacillus 91061|Bacilli L Integron-associated effector binding protein - - - - - - - - - - - - GyrI-like k141_28078_1 1329516.JPST01000005_gene1341 1.74e-08 56.6 COG4974@1|root,COG4974@2|Bacteria,1UXIK@1239|Firmicutes,4I2WD@91061|Bacilli,27D1W@186824|Thermoactinomycetaceae 91061|Bacilli L Phage integrase family - - - - - - - - - - - - Phage_integrase k141_21018_2 1173024.KI912148_gene3151 2.88e-50 168.0 COG0454@1|root,COG0454@2|Bacteria,1GR2B@1117|Cyanobacteria 1117|Cyanobacteria K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_10 k141_17450_1 1294265.JCM21738_4568 1.7e-85 258.0 COG3858@1|root,COG3858@2|Bacteria,1TQK2@1239|Firmicutes,4HBJC@91061|Bacilli,1ZBQC@1386|Bacillus 91061|Bacilli M Glycoside Hydrolase Family yaaH - - ko:K06306 - - - - ko00000 - - - Glyco_hydro_18,LysM k141_31579_1 981383.AEWH01000062_gene2319 8.34e-31 124.0 COG2304@1|root,COG2304@2|Bacteria,1TQHE@1239|Firmicutes,4HBUG@91061|Bacilli 91061|Bacilli S von Willebrand factor type A domain - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - VWA,VWA_2 k141_24772_1 1131730.BAVI_16692 5.68e-34 117.0 COG3763@1|root,COG3763@2|Bacteria,1VEJC@1239|Firmicutes,4HNN9@91061|Bacilli,1ZHYQ@1386|Bacillus 91061|Bacilli S UPF0154 protein yneF - - ko:K09976 - - - - ko00000 - - - UPF0154 k141_20058_1 501479.ACNW01000050_gene3529 2.38e-66 204.0 COG0723@1|root,COG0723@2|Bacteria,1RAA2@1224|Proteobacteria,2TTT2@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis petA - 1.10.2.2 ko:K00411 ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152 - - ko00000,ko00001,ko00002,ko01000 - - - Rieske,UCR_Fe-S_N k141_20058_2 1123237.Salmuc_01425 3.72e-37 135.0 COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,2TSZ3@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis petB - - ko:K00410,ko:K00412 ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152 - - ko00000,ko00001,ko00002,ko03029 - - - Cytochrom_B_C,Cytochrom_C1,Cytochrome_B k141_16394_1 218284.CCDN010000005_gene3161 7.75e-249 691.0 COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HB3V@91061|Bacilli,1ZB8V@1386|Bacillus 91061|Bacilli IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II alkK - - ko:K00666 - - - - ko00000,ko01000,ko01004 - - - AMP-binding,AMP-binding_C k141_28079_1 1117314.PCIT_00493 5.76e-15 79.7 COG1404@1|root,COG2374@1|root,COG1404@2|Bacteria,COG2374@2|Bacteria,1MX52@1224|Proteobacteria,1RMHH@1236|Gammaproteobacteria,2Q0R9@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria L extracellular nuclease - - - ko:K07004 - - - - ko00000 - - - Cadherin,Exo_endo_phos,LTD,PPC k141_29467_2 546274.EIKCOROL_01054 9.17e-44 146.0 COG3536@1|root,COG3536@2|Bacteria,1MZ5M@1224|Proteobacteria,2VR9K@28216|Betaproteobacteria,2KREN@206351|Neisseriales 206351|Neisseriales S Protein of unknown function (DUF971) - - - - - - - - - - - - DUF971 k141_29467_3 1279017.AQYJ01000027_gene1934 1.21e-239 674.0 COG1785@1|root,COG1785@2|Bacteria,1MXI2@1224|Proteobacteria,1RNG8@1236|Gammaproteobacteria,46460@72275|Alteromonadaceae 1236|Gammaproteobacteria P Belongs to the alkaline phosphatase family phoA - 3.1.3.1 ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 M00126 R02135,R04620 RC00017 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 - - - Alk_phosphatase k141_26084_1 1196031.ALEG01000054_gene5540 1.8e-36 129.0 COG5424@1|root,COG5424@2|Bacteria,1U9RZ@1239|Firmicutes,4IJYC@91061|Bacilli,1ZEM6@1386|Bacillus 91061|Bacilli H Iron-containing redox enzyme - - 1.3.3.11 ko:K06137 - - - - ko00000,ko01000 - - - Haem_oxygenas_2 k141_7098_1 218284.CCDN010000002_gene2855 8.1e-214 635.0 COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1TQ0B@1239|Firmicutes,4HA4G@91061|Bacilli,1ZBFF@1386|Bacillus 91061|Bacilli E glutamate synthase gltA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14,1.4.7.1 ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 - R00021,R00093,R00114,R00248,R10086 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - GATase_2,GXGXG,Glu_syn_central,Glu_synthase k141_1099_1 1042375.AFPL01000016_gene52 1.4e-196 556.0 COG0477@1|root,COG2814@2|Bacteria,1MV8D@1224|Proteobacteria,1RNF0@1236|Gammaproteobacteria,465D8@72275|Alteromonadaceae 1236|Gammaproteobacteria EGP COG0477 Permeases of the major facilitator superfamily - - - - - - - - - - - - MFS_1 k141_9460_1 690850.Desaf_0281 3.44e-21 94.7 COG4783@1|root,COG4783@2|Bacteria,1QUMJ@1224|Proteobacteria,43BM7@68525|delta/epsilon subdivisions,2X6ZD@28221|Deltaproteobacteria,2MH97@213115|Desulfovibrionales 28221|Deltaproteobacteria M PFAM peptidase M48 Ste24p - - - - - - - - - - - - Peptidase_M48 k141_12987_1 1453501.JELR01000002_gene568 6.05e-25 105.0 COG2199@1|root,COG3706@2|Bacteria,1MWHH@1224|Proteobacteria,1RRU7@1236|Gammaproteobacteria,465TD@72275|Alteromonadaceae 1236|Gammaproteobacteria T 7TMR-DISM extracellular 2 - - - - - - - - - - - - 7TMR-DISMED2,7TMR-DISM_7TM,GGDEF k141_34259_1 1166948.JPZL01000003_gene787 1.26e-10 62.0 COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,1RNPY@1236|Gammaproteobacteria,1XHJ5@135619|Oceanospirillales 135619|Oceanospirillales O protease - - - ko:K08303 ko05120,map05120 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_U32,Peptidase_U32_C k141_34259_2 1071679.BG57_11195 8.6e-70 220.0 COG0604@1|root,COG0604@2|Bacteria,1MXUX@1224|Proteobacteria,2VHPT@28216|Betaproteobacteria,1K07F@119060|Burkholderiaceae 28216|Betaproteobacteria C alcohol dehydrogenase - - - - - - - - - - - - ADH_N,ADH_zinc_N k141_7099_2 218284.CCDN010000007_gene3871 2.46e-25 100.0 2E7FP@1|root,331YK@2|Bacteria,1VH7K@1239|Firmicutes,4HP5P@91061|Bacilli,1ZI73@1386|Bacillus 91061|Bacilli - - gvpQ - - - - - - - - - - - - k141_17453_1 218284.CCDN010000007_gene3793 3.08e-79 236.0 COG0594@1|root,COG0594@2|Bacteria,1VA78@1239|Firmicutes,4HKG6@91061|Bacilli,1ZHUH@1386|Bacillus 91061|Bacilli J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme rnpA GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0031123,GO:0031404,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904 3.1.26.5 ko:K03536 - - - - ko00000,ko01000,ko03016 - - - Ribonuclease_P k141_35547_1 1279017.AQYJ01000023_gene3169 3.75e-49 161.0 COG1905@1|root,COG1905@2|Bacteria,1MWS2@1224|Proteobacteria,1RN4C@1236|Gammaproteobacteria,46AS7@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1905 NADH ubiquinone oxidoreductase 24 kD subunit nuoE GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0048037,GO:0050136,GO:0051536,GO:0051537,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 ko:K00334 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - iYL1228.KPN_02675 2Fe-2S_thioredx k141_35547_2 1279017.AQYJ01000023_gene3168 2.09e-258 714.0 COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,1RMUD@1236|Gammaproteobacteria,46546@72275|Alteromonadaceae 1236|Gammaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain nuoF GO:0000166,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0010181,GO:0015980,GO:0016020,GO:0030964,GO:0032553,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0048037,GO:0050662,GO:0051287,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.6.5.3 ko:K00335 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_51K,NADH_4Fe-4S,SLBB k141_35547_3 1279017.AQYJ01000023_gene3167 0.0 1061.0 COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,1RMUH@1236|Gammaproteobacteria,464RK@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G) nuoG GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0048037,GO:0050136,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 ko:K00336 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - iECs_1301.ECs3167,iG2583_1286.G2583_2820,iZ_1308.Z3542 Fer2_4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3 k141_37660_1 218284.CCDN010000001_gene1117 9.07e-146 421.0 COG0079@1|root,COG0079@2|Bacteria,1TPUV@1239|Firmicutes,4HA1H@91061|Bacilli,1ZBYJ@1386|Bacillus 91061|Bacilli E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily hisC - 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k141_3266_1 1384057.CD33_03440 5.79e-69 229.0 COG2409@1|root,COG2409@2|Bacteria,1TQ7C@1239|Firmicutes,4H9XX@91061|Bacilli,3IW97@400634|Lysinibacillus 91061|Bacilli S MMPL family - - - ko:K06994 - - - - ko00000 - - - MMPL k141_2009_1 1453501.JELR01000002_gene695 7.57e-53 179.0 COG0705@1|root,COG0705@2|Bacteria,1MYPM@1224|Proteobacteria,1RN1K@1236|Gammaproteobacteria,463ZC@72275|Alteromonadaceae 1236|Gammaproteobacteria S membrane protein (homolog of Drosophila rhomboid) glpG GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019219,GO:0019222,GO:0019538,GO:0031224,GO:0031226,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042802,GO:0043170,GO:0043565,GO:0044212,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:0140096,GO:1901363,GO:1901564,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - ko:K02441 - - - - ko00000 - - - NRho,Rhomboid,Rhomboid_N k141_2009_2 1279017.AQYJ01000028_gene2164 3e-211 591.0 COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,1RND5@1236|Gammaproteobacteria,464ZN@72275|Alteromonadaceae 1236|Gammaproteobacteria CH COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases visC GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016491,GO:0019168,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901576,GO:1901661,GO:1901663 - ko:K03184,ko:K18800 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04987,R06146,R08768,R08775 RC00046,RC01254 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_3 k141_20060_1 218284.CCDN010000001_gene701 2.65e-55 183.0 2BJ57@1|root,32DEE@2|Bacteria,1V93H@1239|Firmicutes,4HN71@91061|Bacilli,1ZH00@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF1510) yrrS - - - - - - - - - - - DUF1510 k141_11845_1 1117647.M5M_16130 8.91e-19 86.7 COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,1RMT7@1236|Gammaproteobacteria,1J52J@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - DUF885 k141_11845_2 78398.KS43_02395 5.43e-84 259.0 COG3741@1|root,COG3741@2|Bacteria 2|Bacteria E N-formylglutamate amidohydrolase hutG - 3.5.1.68,3.5.3.8 ko:K01458,ko:K01479 ko00340,ko00630,ko01100,map00340,map00630,map01100 M00045 R00525,R02285 RC00165,RC00221,RC00323,RC00681 ko00000,ko00001,ko00002,ko01000 - - - FGase k141_29468_1 316057.RPD_4057 1.12e-07 53.9 COG0411@1|root,COG0411@2|Bacteria,1MX51@1224|Proteobacteria,2TTG6@28211|Alphaproteobacteria,3JUVS@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Function proposed based on presence of conserved amino acid motif, structural feature or limited homology MA20_23480 - - ko:K01995 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C k141_29468_2 1209072.ALBT01000035_gene1470 1.2e-92 287.0 COG0609@1|root,COG0609@2|Bacteria,1MV9W@1224|Proteobacteria,1RMDF@1236|Gammaproteobacteria,1FHNH@10|Cellvibrio 1236|Gammaproteobacteria P FecCD transport family btuC - - ko:K02015 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - FecCD k141_17454_1 1294265.JCM21738_4679 4.68e-142 404.0 COG4990@1|root,COG4990@2|Bacteria,1V714@1239|Firmicutes,4HCDQ@91061|Bacilli,1ZB75@1386|Bacillus 91061|Bacilli S Peptidase_C39 like family - - - - - - - - - - - - Peptidase_C39_2 k141_34260_2 218284.CCDN010000005_gene3455 7.5e-97 286.0 COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,4H9V0@91061|Bacilli,1ZBBP@1386|Bacillus 91061|Bacilli O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides ppiA GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 - - - ko00000,ko00001,ko01000,ko03110,ko04147 - - - Pro_isomerase k141_35548_1 1294265.JCM21738_4646 4.14e-13 66.2 COG3832@1|root,COG3832@2|Bacteria,1V42G@1239|Firmicutes,4HH5K@91061|Bacilli 91061|Bacilli S Activator of Hsp90 ATPase homolog 1-like protein - - - - - - - - - - - - AHSA1 k141_35548_2 1294265.JCM21738_4648 3.29e-93 272.0 2CHCP@1|root,32S5R@2|Bacteria,1V3HI@1239|Firmicutes,4HGYA@91061|Bacilli,1ZFKK@1386|Bacillus 91061|Bacilli S Domain of unknown function (DU1801) - - - - - - - - - - - - DUF1801 k141_20061_1 1385510.N781_14010 1.61e-35 136.0 COG1657@1|root,COG1657@2|Bacteria,1TRRG@1239|Firmicutes,4HA2Q@91061|Bacilli,2YB92@289201|Pontibacillus 91061|Bacilli I Squalene-hopene cyclase C-terminal domain sqhC - 4.2.1.137 ko:K18115 - - - - ko00000,ko01000 - - - SQHop_cyclase_C,SQHop_cyclase_N k141_7100_1 1122915.AUGY01000014_gene2735 7.99e-92 291.0 COG1376@1|root,COG1376@2|Bacteria,1U2DJ@1239|Firmicutes,4IBZC@91061|Bacilli,271R4@186822|Paenibacillaceae 91061|Bacilli S L,D-transpeptidase catalytic domain - - - - - - - - - - - - YkuD k141_3267_1 218284.CCDN010000006_gene3670 1.92e-134 394.0 COG0793@1|root,COG0793@2|Bacteria,1TPBI@1239|Firmicutes,4HAKE@91061|Bacilli,1ZBDE@1386|Bacillus 91061|Bacilli M Belongs to the peptidase S41A family ctpB GO:0003674,GO:0003824,GO:0004175,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008233,GO:0009653,GO:0009987,GO:0016787,GO:0019538,GO:0023052,GO:0030154,GO:0030288,GO:0030313,GO:0030435,GO:0031975,GO:0032502,GO:0033218,GO:0034641,GO:0042277,GO:0042597,GO:0042802,GO:0042803,GO:0043170,GO:0043603,GO:0043900,GO:0043902,GO:0043934,GO:0044237,GO:0044238,GO:0044464,GO:0046983,GO:0048518,GO:0048522,GO:0048646,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070011,GO:0071704,GO:0140096,GO:1900190,GO:1900192,GO:1901564 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - PDZ,PDZ_2,PG_binding_1,Peptidase_S41 k141_15130_1 1116375.VEJY3_06065 3.17e-64 201.0 COG2949@1|root,COG2949@2|Bacteria,1MURW@1224|Proteobacteria,1RMG7@1236|Gammaproteobacteria,1XSGW@135623|Vibrionales 135623|Vibrionales S SanA protein sanA - - ko:K03748 - - - - ko00000 - - - DUF218 k141_33255_1 1205908.AKXW01000108_gene1282 4.73e-133 382.0 COG2273@1|root,COG2273@2|Bacteria,1RANY@1224|Proteobacteria,1SIGK@1236|Gammaproteobacteria,1XX6K@135623|Vibrionales 135623|Vibrionales G Exported glycosyl hydrolase, family 16 - - - - - - - - - - - - Glyco_hydro_16 k141_3511_1 1450694.BTS2_3072 7.97e-58 190.0 COG3869@1|root,COG3869@2|Bacteria,1TPBA@1239|Firmicutes,4HC6U@91061|Bacilli,1ZBJU@1386|Bacillus 91061|Bacilli E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity mcsB GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 ko:K19405 - - R11090 RC00002,RC00203 ko00000,ko01000 - - - ATP-gua_Ptrans k141_3511_2 1196324.A374_17564 4.52e-08 53.1 COG3880@1|root,COG3880@2|Bacteria,1V6YM@1239|Firmicutes,4HH4R@91061|Bacilli 91061|Bacilli S protein with conserved CXXC pairs mcsA GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 - ko:K19411 - - - - ko00000 - - - UVR k141_4719_1 1118054.CAGW01000075_gene3277 2.65e-17 82.0 COG1651@1|root,COG1651@2|Bacteria,1V6IC@1239|Firmicutes,4HKJU@91061|Bacilli,26RRT@186822|Paenibacillaceae 91061|Bacilli O Thioredoxin bdbD - - - - - - - - - - - Thioredoxin_4 k141_36628_2 1279017.AQYJ01000024_gene1013 7.56e-221 620.0 COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,1RNQ8@1236|Gammaproteobacteria,463YI@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) hemA GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006536,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008883,GO:0009058,GO:0009064,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019353,GO:0019438,GO:0019752,GO:0033013,GO:0033014,GO:0033526,GO:0034641,GO:0042168,GO:0042440,GO:0042802,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.2.1.70 ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R04109 RC00055,RC00149 ko00000,ko00001,ko00002,ko01000 - - iECNA114_1301.ECNA114_1375,iECSF_1327.ECSF_1186,iUTI89_1310.UTI89_C1404 GlutR_N,GlutR_dimer,Shikimate_DH k141_8161_1 218284.CCDN010000011_gene4416 2.61e-142 409.0 COG0013@1|root,COG0013@2|Bacteria,1TSBZ@1239|Firmicutes,4HADV@91061|Bacilli,1ZDMJ@1386|Bacillus 91061|Bacilli J metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain alaS_2 - 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DHHA1,tRNA-synt_2c,tRNA_SAD k141_21358_1 1453501.JELR01000002_gene889 0.0 1449.0 COG2352@1|root,COG2352@2|Bacteria,1MUD5@1224|Proteobacteria,1RPTP@1236|Gammaproteobacteria,4646H@72275|Alteromonadaceae 1236|Gammaproteobacteria C Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle ppc GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0008964,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0055114,GO:0071704,GO:0072350 4.1.1.31 ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 M00168,M00170,M00171,M00172,M00173,M00346,M00374 R00345 RC02741 ko00000,ko00001,ko00002,ko01000 - - iSFV_1184.SFV_4025 PEPcase k141_21358_2 1042377.AFPJ01000051_gene80 1.96e-70 226.0 COG5430@1|root,COG5430@2|Bacteria 2|Bacteria S Spore Coat Protein U domain - - - - - - - - - - - - SCPU k141_21358_3 1502850.FG91_01953 9.84e-43 171.0 COG3188@1|root,COG3188@2|Bacteria,1MWV6@1224|Proteobacteria,2TU95@28211|Alphaproteobacteria,2K0VE@204457|Sphingomonadales 204457|Sphingomonadales NU P pilus assembly protein porin PapC - - - ko:K07347 ko05133,map05133 - - - ko00000,ko00001,ko02000,ko02035,ko02044 1.B.11.3 - - Usher k141_33286_1 218284.CCDN010000004_gene3110 4.76e-05 46.6 COG2334@1|root,COG2334@2|Bacteria 2|Bacteria S homoserine kinase activity hsk - 2.7.1.39 ko:K02204 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 M00018 R01771 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - APH,HTH_18 k141_33286_2 1131730.BAVI_05484 3.26e-94 283.0 COG0715@1|root,COG0715@2|Bacteria,1TPAD@1239|Firmicutes,4HBR9@91061|Bacilli,1ZCIY@1386|Bacillus 91061|Bacilli P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components M1-596 - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1 k141_2376_3 1453501.JELR01000002_gene437 7.55e-88 258.0 COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,1S4H7@1236|Gammaproteobacteria,4674B@72275|Alteromonadaceae 1236|Gammaproteobacteria K Belongs to the Fur family fur - - ko:K03711 - - - - ko00000,ko03000 - - - FUR k141_3546_1 218284.CCDN010000006_gene3592 3.1e-49 158.0 COG3125@1|root,COG3125@2|Bacteria 2|Bacteria C oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor qoxD GO:0003674,GO:0003824,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016679,GO:0016682,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.10.3.12 ko:K02829 ko00190,ko01100,map00190,map01100 M00416 R09492 RC00819 ko00000,ko00001,ko00002,ko01000 - - - COX4_pro k141_8180_1 1385511.N783_14685 1.32e-82 256.0 COG2199@1|root,COG2199@2|Bacteria,1V5DB@1239|Firmicutes,4HI16@91061|Bacilli,2YAAV@289201|Pontibacillus 91061|Bacilli T Histidine kinase - - - - - - - - - - - - GGDEF,PAS_3 k141_33287_2 1453501.JELR01000001_gene3185 8.52e-99 290.0 COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,1RQPJ@1236|Gammaproteobacteria,466I2@72275|Alteromonadaceae 1236|Gammaproteobacteria L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group ruvC GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 ko:K01159 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvC k141_2377_1 1453501.JELR01000001_gene1987 1.48e-35 127.0 COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,1RMHI@1236|Gammaproteobacteria,464B8@72275|Alteromonadaceae 1236|Gammaproteobacteria U Belongs to the peptidase S26 family lepB GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24,Peptidase_S26 k141_31781_1 1279017.AQYJ01000025_gene547 8.1e-228 644.0 COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,1RMSR@1236|Gammaproteobacteria,4646K@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the peptidase S41A family prc GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016787,GO:0019538,GO:0023052,GO:0030163,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - BAGE,DUF3340,PDZ,Peptidase_S41 k141_21359_1 218284.CCDN010000001_gene731 1.04e-128 375.0 COG0635@1|root,COG0635@2|Bacteria,1TPES@1239|Firmicutes,4HA60@91061|Bacilli,1ZC7V@1386|Bacillus 91061|Bacilli H Involved in the biosynthesis of porphyrin-containing compound hemN GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - - - - - - - - - - HemN_C,Radical_SAM k141_15331_2 869213.JCM21142_31049 4.18e-08 58.2 COG0711@1|root,COG0711@2|Bacteria,4NQKA@976|Bacteroidetes,47Q9K@768503|Cytophagia 976|Bacteroidetes C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) atpF - - ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_B k141_3548_1 653045.Strvi_7628 1.33e-47 167.0 COG3328@1|root,COG3328@2|Bacteria,2GM8F@201174|Actinobacteria 201174|Actinobacteria L Transposase - - - - - - - - - - - - Transposase_mut k141_8181_1 1453501.JELR01000005_gene1582 1.91e-97 298.0 COG2273@1|root,COG2273@2|Bacteria,1NFHX@1224|Proteobacteria,1RRPK@1236|Gammaproteobacteria,463ZT@72275|Alteromonadaceae 1236|Gammaproteobacteria G Beta-glucanase Beta-glucan synthetase - - - - - - - - - - - - Glyco_hydro_16 k141_36660_4 1042377.AFPJ01000051_gene60 1.64e-65 200.0 COG2913@1|root,COG2913@2|Bacteria,1N6YW@1224|Proteobacteria,1SCTT@1236|Gammaproteobacteria,468DR@72275|Alteromonadaceae 1236|Gammaproteobacteria M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamE GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0030674,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0042221,GO:0042802,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045203,GO:0045229,GO:0046677,GO:0050896,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0060090,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - ko:K06186 - - - - ko00000,ko02000 1.B.33.1 - - SmpA_OmlA k141_36660_7 1042377.AFPJ01000051_gene63 1.71e-281 776.0 COG0733@1|root,COG0733@2|Bacteria,1MUZJ@1224|Proteobacteria,1RPCT@1236|Gammaproteobacteria,464UT@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0733 Na -dependent transporters of the SNF family - - - ko:K03308 - - - - ko00000 2.A.22.4,2.A.22.5 - - SNF k141_36660_9 1279017.AQYJ01000028_gene2493 3.2e-222 622.0 COG0733@1|root,COG0733@2|Bacteria,1MUZJ@1224|Proteobacteria,1RPCT@1236|Gammaproteobacteria,4657F@72275|Alteromonadaceae 1236|Gammaproteobacteria S Sodium:neurotransmitter symporter family - - - ko:K03308 - - - - ko00000 2.A.22.4,2.A.22.5 - - SNF k141_28409_1 218284.CCDN010000008_gene4215 3.37e-212 590.0 COG1488@1|root,COG1488@2|Bacteria,1TPDW@1239|Firmicutes,4HAI4@91061|Bacilli,1ZCGY@1386|Bacillus 91061|Bacilli H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP pncB2 - 6.3.4.21 ko:K00763 ko00760,ko01100,map00760,map01100 - R01724 RC00033 ko00000,ko00001,ko01000 - - - QRPTase_C,QRPTase_N k141_28409_2 218284.CCDN010000008_gene4216 4.66e-17 79.0 28Z61@1|root,2ZKYB@2|Bacteria,1W2RA@1239|Firmicutes,4HSNT@91061|Bacilli,1ZIVH@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_31782_1 675806.VII_000008 5.62e-77 236.0 COG1073@1|root,COG1073@2|Bacteria,1MUCD@1224|Proteobacteria,1RPCZ@1236|Gammaproteobacteria,1XYUQ@135623|Vibrionales 135623|Vibrionales S X-Pro dipeptidyl-peptidase (S15 family) - - - ko:K06889 - - - - ko00000 - - - Peptidase_S15 k141_31782_2 1116375.VEJY3_17856 1.76e-34 124.0 COG0716@1|root,COG0716@2|Bacteria,1N002@1224|Proteobacteria,1S98G@1236|Gammaproteobacteria,1Y0G5@135623|Vibrionales 135623|Vibrionales C Flavodoxin - - - - - - - - - - - - Flavodoxin_4 k141_33290_1 218284.CCDN010000009_gene4320 1.6e-171 486.0 COG0477@1|root,COG2814@2|Bacteria,1TS3C@1239|Firmicutes,4HC3B@91061|Bacilli,1ZS79@1386|Bacillus 91061|Bacilli EGP Nucleoside H+ symporter ywbF - - ko:K05820 - - - - ko00000,ko02000 2.A.1.27 - - MFS_1_like k141_36662_1 1033740.CAEW01000026_gene551 1.46e-52 176.0 COG3409@1|root,COG5632@1|root,COG3409@2|Bacteria,COG5632@2|Bacteria,1V3JT@1239|Firmicutes,4HJQH@91061|Bacilli,26G7X@186818|Planococcaceae 91061|Bacilli M Ami_2 - - 3.5.1.28 ko:K01447 - - R04112 RC00064,RC00141 ko00000,ko01000 - - - Amidase_2,PG_binding_1 k141_31783_1 42565.FP66_14315 5.09e-111 342.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XHGD@135619|Oceanospirillales 135619|Oceanospirillales T signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - - - - - - - - - - CBS,EAL,GGDEF,PAS_9 k141_36663_1 218284.CCDN010000005_gene3228 6.68e-109 343.0 COG3857@1|root,COG3857@2|Bacteria,1TQJW@1239|Firmicutes,4HAY6@91061|Bacilli,1ZC70@1386|Bacillus 91061|Bacilli L ATP-dependent helicase deoxyribonuclease subunit B rexB GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0004527,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.6.4.12 ko:K16899 - - - - ko00000,ko01000,ko03400 - - - Exonuc_V_gamma,PDDEXK_1,UvrD_C k141_28411_1 1453501.JELR01000002_gene856 9.82e-151 436.0 COG1040@1|root,COG1040@2|Bacteria,1REX9@1224|Proteobacteria,1S568@1236|Gammaproteobacteria,4671D@72275|Alteromonadaceae 1236|Gammaproteobacteria S competence protein - - - - - - - - - - - - - k141_33291_1 1231057.AMGD01000033_gene1756 2.77e-32 120.0 COG0115@1|root,COG0115@2|Bacteria,1TPY2@1239|Firmicutes,4HC7T@91061|Bacilli,26DTV@186818|Planococcaceae 91061|Bacilli E Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family ilvE - 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_4 k141_15333_2 1444306.JFZC01000004_gene1668 5.55e-31 122.0 COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,4HAJM@91061|Bacilli 91061|Bacilli P abc transporter atp-binding protein M1-1085 - - ko:K16786,ko:K16787 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran k141_31784_1 1294265.JCM21738_1999 2.85e-105 316.0 COG1823@1|root,COG1823@2|Bacteria,1UPUK@1239|Firmicutes,4HAJY@91061|Bacilli,1ZB7C@1386|Bacillus 91061|Bacilli U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family tcyP - - ko:K06956 - - - - ko00000 - - - SDF k141_28412_1 1453501.JELR01000001_gene1811 2e-93 285.0 COG4325@1|root,COG4325@2|Bacteria,1MXTM@1224|Proteobacteria,1RNYZ@1236|Gammaproteobacteria,466NZ@72275|Alteromonadaceae 1236|Gammaproteobacteria S Predicted membrane protein (DUF2254) - - - - - - - - - - - - DUF2254 k141_21362_2 1279017.AQYJ01000027_gene1681 8.25e-117 340.0 COG2180@1|root,COG2180@2|Bacteria,1MY4E@1224|Proteobacteria,1RQ23@1236|Gammaproteobacteria,46590@72275|Alteromonadaceae 1236|Gammaproteobacteria C Nitrate reductase, delta subunit narJ - - ko:K00373 ko02020,map02020 - - - ko00000,ko00001 - - - Nitrate_red_del k141_36665_2 1528106.JRJE01000005_gene1224 2.05e-23 93.2 COG3335@1|root,COG3335@2|Bacteria,1P76X@1224|Proteobacteria,2U16U@28211|Alphaproteobacteria,2JSK6@204441|Rhodospirillales 204441|Rhodospirillales L Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - - - - - - - - - - DDE_3 k141_21364_1 1453501.JELR01000002_gene633 6.31e-34 125.0 COG0463@1|root,COG0463@2|Bacteria,1RBHD@1224|Proteobacteria,1S3K4@1236|Gammaproteobacteria,4686Z@72275|Alteromonadaceae 1236|Gammaproteobacteria M Glycosyl transferase, family 2 - - - - - - - - - - - - Glycos_transf_2 k141_3555_2 1042377.AFPJ01000028_gene2204 7.9e-111 328.0 COG3713@1|root,COG3713@2|Bacteria,1N3RD@1224|Proteobacteria,1SAIX@1236|Gammaproteobacteria,468UZ@72275|Alteromonadaceae 1236|Gammaproteobacteria M MltA-interacting protein MipA - - - ko:K07274 - - - - ko00000,ko02000 9.B.99.1 - - MipA k141_15334_1 1123270.ATUR01000003_gene694 1.73e-40 139.0 COG1416@1|root,COG1416@2|Bacteria,1RI2V@1224|Proteobacteria,2U98Z@28211|Alphaproteobacteria,2K5CI@204457|Sphingomonadales 204457|Sphingomonadales S DsrE/DsrF-like family - - - - - - - - - - - - DrsE k141_15334_2 1283300.ATXB01000001_gene419 3.63e-87 277.0 2C593@1|root,2Z84R@2|Bacteria,1Q8PC@1224|Proteobacteria,1RP26@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_21365_1 218284.CCDN010000005_gene3492 4.16e-100 310.0 COG1368@1|root,COG1368@2|Bacteria,1TRMA@1239|Firmicutes,4H9S0@91061|Bacilli,1ZBBV@1386|Bacillus 91061|Bacilli M Belongs to the LTA synthase family yfnI GO:0005575,GO:0005576 2.7.8.20 ko:K19005 ko00561,ko01100,map00561,map01100 - R05081,R10849 RC00017 ko00000,ko00001,ko01000 - - - Sulfatase k141_36667_1 118166.JH976537_gene77 2e-96 292.0 COG2066@1|root,COG2066@2|Bacteria,1G1IK@1117|Cyanobacteria,1H7V2@1150|Oscillatoriales 1117|Cyanobacteria E Belongs to the glutaminase family - - 3.5.1.2 ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 - R00256,R01579 RC00010,RC02798 ko00000,ko00001,ko01000 - - - Glutaminase k141_28415_2 997296.PB1_01240 4.95e-51 163.0 COG2739@1|root,COG2739@2|Bacteria,1VEGP@1239|Firmicutes,4HKK6@91061|Bacilli,1ZH7Z@1386|Bacillus 91061|Bacilli S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein ylxM GO:0003674,GO:0008150,GO:0030234,GO:0030695,GO:0050790,GO:0060589,GO:0065007,GO:0065009,GO:0098772 - ko:K09787 - - - - ko00000 - - - UPF0122 k141_8183_2 674977.VMC_19920 6.66e-71 214.0 COG2315@1|root,COG2315@2|Bacteria,1N12P@1224|Proteobacteria,1S8W4@1236|Gammaproteobacteria,1XXKZ@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria - - - - - - - - - - - - YjbR k141_8183_3 1116375.VEJY3_08250 8.47e-92 270.0 COG1846@1|root,COG1846@2|Bacteria,1RJIU@1224|Proteobacteria,1SY8V@1236|Gammaproteobacteria,1XX4I@135623|Vibrionales 135623|Vibrionales K helix_turn_helix multiple antibiotic resistance protein - - - - - - - - - - - - MarR k141_8183_4 1116375.VEJY3_08255 1.43e-158 449.0 COG0697@1|root,COG0697@2|Bacteria,1MY0D@1224|Proteobacteria,1S001@1236|Gammaproteobacteria,1XV8D@135623|Vibrionales 135623|Vibrionales EG of the drug metabolite transporter (DMT) superfamily - - - - - - - - - - - - EamA k141_30645_1 1116375.VEJY3_20336 1.21e-173 491.0 COG0508@1|root,COG0508@2|Bacteria,1MVDC@1224|Proteobacteria,1RQ9Y@1236|Gammaproteobacteria,1XV98@135623|Vibrionales 135623|Vibrionales C COG0508 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes pdhC - 2.3.1.12 ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding k141_30645_2 1116375.VEJY3_20331 6.91e-233 641.0 COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,1RP3G@1236|Gammaproteobacteria,1XV36@135623|Vibrionales 135623|Vibrionales C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit pdhB - 1.2.4.1 ko:K00162,ko:K21417 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C k141_30645_3 1116375.VEJY3_20326 3.45e-263 721.0 COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,1RREX@1236|Gammaproteobacteria,1XUF6@135623|Vibrionales 135623|Vibrionales C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit pdhA - 1.2.4.1 ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh k141_30645_4 1116375.VEJY3_20321 2.64e-67 204.0 COG3805@1|root,COG3805@2|Bacteria,1N2DN@1224|Proteobacteria,1SA51@1236|Gammaproteobacteria,1XYIR@135623|Vibrionales 135623|Vibrionales Q COG3805 Aromatic ring-cleaving dioxygenase - - - ko:K10253 - - - - ko00000,ko01000 - - - DOPA_dioxygen k141_21366_1 1453501.JELR01000001_gene2216 1.32e-21 99.0 COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,1RMDS@1236|Gammaproteobacteria,464FV@72275|Alteromonadaceae 1236|Gammaproteobacteria J Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs rne - 3.1.26.12 ko:K08300 ko03018,map03018 M00394 - - ko00000,ko00001,ko00002,ko01000,ko03009,ko03019 - - - RNase_E_G,S1 k141_31785_1 278963.ATWD01000001_gene2061 2.94e-78 245.0 COG2025@1|root,COG2025@2|Bacteria,3Y3JE@57723|Acidobacteria,2JM9U@204432|Acidobacteriia 204432|Acidobacteriia C Electron transfer flavoprotein FAD-binding domain - - - ko:K03522 - - - - ko00000,ko04147 - - - ETF,ETF_alpha k141_31785_2 243090.RB7425 7.9e-149 434.0 COG0379@1|root,COG0379@2|Bacteria,2IXB1@203682|Planctomycetes 203682|Planctomycetes H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate nadA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 ko:K03517 ko00760,ko01100,map00760,map01100 M00115 R04292 RC01119 ko00000,ko00001,ko00002,ko01000 - - - NadA k141_8185_1 1453501.JELR01000001_gene1941 4.91e-156 462.0 COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,1RMAP@1236|Gammaproteobacteria,464XP@72275|Alteromonadaceae 1236|Gammaproteobacteria M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamA GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - ko:K07277 - - - - ko00000,ko02000,ko03029 1.B.33 - - Bac_surface_Ag,POTRA k141_28418_1 1294265.JCM21738_405 1.62e-144 422.0 COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1TSSC@1239|Firmicutes,4HA8C@91061|Bacilli,1ZBA6@1386|Bacillus 91061|Bacilli C COG1014 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, gamma subunit korA - 1.2.7.11,1.2.7.3 ko:K00174 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - PFOR_II,POR,POR_N k141_15337_1 42565.FP66_13425 3.05e-63 206.0 COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,1RNQS@1236|Gammaproteobacteria,1XHP7@135619|Oceanospirillales 135619|Oceanospirillales K Participates in both transcription termination and antitermination nusA - - ko:K02600 - - - - ko00000,ko03009,ko03021 - - - HHH_5,KH_5,NusA_N,S1 k141_15337_2 1178482.BJB45_14805 2.14e-20 89.4 COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,1RM9X@1236|Gammaproteobacteria,1XH9T@135619|Oceanospirillales 135619|Oceanospirillales J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB - - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N,IF2_assoc k141_21367_2 301.JNHE01000004_gene1597 1.86e-65 229.0 COG0591@1|root,COG0642@1|root,COG0784@1|root,COG0591@2|Bacteria,COG0784@2|Bacteria,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,1RP2U@1236|Gammaproteobacteria,1YDER@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria T PAS fold - - - - - - - - - - - - HATPase_c,HisKA,PAS_7,Response_reg k141_37953_1 945543.VIBR0546_15336 0.0 947.0 COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,1MUV9@1224|Proteobacteria,1RN8U@1236|Gammaproteobacteria,1XT4K@135623|Vibrionales 135623|Vibrionales C Catalyzes the reversible hydration of fumarate to (S)- malate fumA - 4.2.1.2 ko:K01676 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - - Fumerase,Fumerase_C k141_37953_2 1116375.VEJY3_09970 1.25e-301 825.0 COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,1RMSE@1236|Gammaproteobacteria,1XTES@135623|Vibrionales 135623|Vibrionales EH COG0147 Anthranilate para-aminobenzoate synthases component I pabB - 2.6.1.85 ko:K01665 ko00790,map00790 - R01716 RC00010,RC01418 ko00000,ko00001,ko01000 - - - Anth_synt_I_N,Chorismate_bind k141_37953_3 1116375.VEJY3_09975 2.61e-130 371.0 COG0494@1|root,COG0494@2|Bacteria,1RD2C@1224|Proteobacteria,1SA4Q@1236|Gammaproteobacteria,1XWY8@135623|Vibrionales 135623|Vibrionales L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes nudL - - - - - - - - - - - NUDIX k141_37953_4 1280001.BAOA01000004_gene3748 5.24e-278 763.0 COG0814@1|root,COG0814@2|Bacteria,1NQFA@1224|Proteobacteria,1RQ8Q@1236|Gammaproteobacteria,1XSJ0@135623|Vibrionales 135623|Vibrionales E serine transporter sdaC - - ko:K03837 - - - - ko00000,ko02000 2.A.42.2.1 - - Trp_Tyr_perm k141_37953_5 223926.28806872 0.0 890.0 COG1760@1|root,COG1760@2|Bacteria,1MUZN@1224|Proteobacteria,1RMJZ@1236|Gammaproteobacteria,1XSZW@135623|Vibrionales 135623|Vibrionales E COG1760 L-serine deaminase sdaA - 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 - R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 - - - SDH_alpha,SDH_beta k141_37953_6 243277.VC_1299 9.95e-88 257.0 COG0720@1|root,COG0720@2|Bacteria,1RI4P@1224|Proteobacteria,1S3T6@1236|Gammaproteobacteria,1XWZ5@135623|Vibrionales 135623|Vibrionales H 6-pyruvoyl tetrahydropterin synthase queD - 4.1.2.50,4.2.3.12 ko:K01737 ko00790,ko01100,map00790,map01100 M00842,M00843 R04286,R09959 RC01117,RC02846,RC02847 ko00000,ko00001,ko00002,ko01000,ko03016 - - - PTPS k141_37953_7 223926.28806884 1.79e-276 769.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XTWZ@135623|Vibrionales 135623|Vibrionales NT methyl-accepting chemotaxis protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal k141_15377_1 1453501.JELR01000002_gene1314 3.78e-51 162.0 COG1598@1|root,COG1598@2|Bacteria 2|Bacteria N PFAM Uncharacterised protein family UPF0150 ycfB - - - - - - - - - - - HicB_lk_antitox k141_38013_1 223926.28805989 4.3e-44 162.0 COG1879@1|root,COG1879@2|Bacteria,1QQQ2@1224|Proteobacteria,1RRG1@1236|Gammaproteobacteria,1XV4R@135623|Vibrionales 135623|Vibrionales G Peptidase M60-like family - - - ko:K21429 - - - - ko00000,ko01002 - - - M60-like_N k141_30734_1 1294265.JCM21738_2283 1.09e-103 319.0 COG2202@1|root,COG5002@1|root,COG2202@2|Bacteria,COG5002@2|Bacteria,1VUBP@1239|Firmicutes,4HUPW@91061|Bacilli,1ZS15@1386|Bacillus 91061|Bacilli T Histidine kinase kinA - 2.7.13.3 ko:K02491 ko02020,map02020 M00485 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - 5TM-5TMR_LYT,HATPase_c,HisKA,MASE3,MHYT,PAS,PAS_3,PAS_4,PAS_9 k141_28495_1 218284.CCDN010000001_gene1736 1.22e-83 263.0 COG0075@1|root,COG3916@1|root,COG0075@2|Bacteria,COG3916@2|Bacteria,1TR3I@1239|Firmicutes,4HA6W@91061|Bacilli,1ZAT2@1386|Bacillus 91061|Bacilli E Aminotransferase class-V - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10,Acetyltransf_5,Acetyltransf_9,Aminotran_5 k141_8258_2 218284.CCDN010000004_gene3061 9.78e-11 61.6 COG0018@1|root,COG0018@2|Bacteria,1TPEZ@1239|Firmicutes,4HAR3@91061|Bacilli,1ZBP1@1386|Bacillus 91061|Bacilli J Arginyl-tRNA synthetase argS GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d k141_38016_2 1453501.JELR01000002_gene134 1.16e-23 100.0 COG2730@1|root,COG2730@2|Bacteria,1PY25@1224|Proteobacteria,1SYWJ@1236|Gammaproteobacteria,4666R@72275|Alteromonadaceae 1236|Gammaproteobacteria G CBD_II - - 3.2.1.4 ko:K01179 ko00500,ko01100,map00500,map01100 - R06200,R11307,R11308 - ko00000,ko00001,ko01000 - GH5,GH9 - CBM_10,CBM_2,CBM_5_12_2,Cellulase,Glyco_hydro_11 k141_8259_1 1116375.VEJY3_21241 1.37e-66 209.0 COG0583@1|root,COG0583@2|Bacteria,1MY68@1224|Proteobacteria,1RSEX@1236|Gammaproteobacteria,1XV82@135623|Vibrionales 135623|Vibrionales K Bacterial regulatory helix-turn-helix protein, lysR family - - - - - - - - - - - - HTH_1,LysR_substrate k141_8259_2 1116375.VEJY3_21246 3.94e-100 297.0 COG2240@1|root,COG2240@2|Bacteria,1MVC9@1224|Proteobacteria,1RMIE@1236|Gammaproteobacteria,1XSHI@135623|Vibrionales 135623|Vibrionales H Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP - - 2.7.1.35 ko:K00868 ko00750,ko01100,map00750,map01100 - R00174,R01909,R02493 RC00002,RC00017 ko00000,ko00001,ko01000 - - - Phos_pyr_kin k141_30736_1 218284.CCDN010000007_gene3917 3.88e-99 290.0 COG3108@1|root,COG3409@1|root,COG3108@2|Bacteria,COG3409@2|Bacteria,1V2G4@1239|Firmicutes,4HRIA@91061|Bacilli,1ZFEE@1386|Bacillus 91061|Bacilli M Peptidase M15 - - 3.4.17.14 ko:K08640 - - - - ko00000,ko01000,ko01002,ko01011 - - - PG_binding_1,Peptidase_M15_3 k141_38017_1 218284.CCDN010000001_gene57 1.03e-48 161.0 COG0543@1|root,COG0543@2|Bacteria,1TQ5D@1239|Firmicutes,4HAU4@91061|Bacilli,1ZBJI@1386|Bacillus 91061|Bacilli C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) pyrK GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042602,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0052875,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - ko:K02823 ko00240,ko01100,map00240,map01100 - - - ko00000,ko00001 - - iYO844.BSU15530 DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1 k141_38017_2 218284.CCDN010000001_gene56 5.28e-80 244.0 COG0167@1|root,COG0167@2|Bacteria,1TPFV@1239|Firmicutes,4HA5H@91061|Bacilli,1ZBNC@1386|Bacillus 91061|Bacilli F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily pyrD GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14 ko:K17828 ko00240,ko01100,map00240,map01100 M00051 R01869 RC00051 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU15540 DHO_dh k141_15379_1 379066.GAU_0803 2.85e-124 386.0 COG2091@1|root,COG2091@2|Bacteria,1ZUQA@142182|Gemmatimonadetes 142182|Gemmatimonadetes H lysine biosynthetic process via aminoadipic acid - - - - - - - - - - - - - k141_28498_1 218284.CCDN010000002_gene2593 6.8e-131 384.0 COG0642@1|root,COG2205@2|Bacteria,1V10X@1239|Firmicutes,4H9UD@91061|Bacilli,1ZS4A@1386|Bacillus 91061|Bacilli T COG0642 Signal transduction histidine kinase yclK - - - - - - - - - - - HAMP,HATPase_c,HisKA k141_36735_1 1116375.VEJY3_03320 2.5e-161 468.0 COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,1RN9H@1236|Gammaproteobacteria,1XTJ2@135623|Vibrionales 135623|Vibrionales M Catalyzes cross-linking of the peptidoglycan cell wall mrdA - 3.4.16.4 ko:K05515 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - - PBP_dimer,Transpeptidase k141_18038_1 102107.XP_008237291.1 5.01e-70 229.0 COG0807@1|root,KOG1284@2759|Eukaryota,37KWS@33090|Viridiplantae,3GB0Y@35493|Streptophyta,4JGCD@91835|fabids 35493|Streptophyta H riboflavin biosynthesis protein - GO:0003674,GO:0003824,GO:0003933,GO:0003935,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016020,GO:0016787,GO:0016810,GO:0016814,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0019238,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.5.4.25,4.1.99.12 ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 M00125,M00840 R00425,R07281 RC00293,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 - - - DHBP_synthase,GTP_cyclohydro2 k141_1287_1 1453500.AT05_10785 1.09e-07 53.5 COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,1HXA1@117743|Flavobacteriia 976|Bacteroidetes S ATPase family associated with various cellular activities (AAA) moxR - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 k141_33408_1 1476583.DEIPH_ctg029orf0022 2.35e-10 66.2 COG3947@1|root,COG3947@2|Bacteria 2|Bacteria T sequence-specific DNA binding - - - - - - - - - - - - BTAD k141_9639_1 218284.CCDN010000002_gene1992 3.5e-301 827.0 COG0138@1|root,COG0138@2|Bacteria,1TPQ5@1239|Firmicutes,4H9YY@91061|Bacilli,1ZD5E@1386|Bacillus 91061|Bacilli F Bifunctional purine biosynthesis protein PurH purH - 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 - - - AICARFT_IMPCHas,MGS k141_28726_1 218284.CCDN010000002_gene1990 3.34e-150 427.0 COG0150@1|root,COG0150@2|Bacteria,1TP9J@1239|Firmicutes,4HABW@91061|Bacilli,1ZBPS@1386|Bacillus 91061|Bacilli F Phosphoribosylformylglycinamidine cyclo-ligase purM - 6.3.3.1 ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04208 RC01100 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C k141_13258_1 1453501.JELR01000002_gene535 1.39e-108 325.0 COG1162@1|root,COG1162@2|Bacteria,1MUEF@1224|Proteobacteria,1RMMB@1236|Gammaproteobacteria,465K2@72275|Alteromonadaceae 1236|Gammaproteobacteria S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit rsgA2 - 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 - R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 - - - RsgA_GTPase k141_16788_1 1219076.N646_4143 1.55e-41 145.0 COG1161@1|root,COG1161@2|Bacteria,1MV5H@1224|Proteobacteria,1RP79@1236|Gammaproteobacteria,1XSKP@135623|Vibrionales 135623|Vibrionales S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity rbgA - - ko:K14540 - - - - ko00000,ko03009 - - - MMR_HSR1 k141_16788_2 1116375.VEJY3_19116 2.28e-118 339.0 COG0454@1|root,COG0456@2|Bacteria,1N4MF@1224|Proteobacteria,1S66R@1236|Gammaproteobacteria,1XWDA@135623|Vibrionales 135623|Vibrionales K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - - - - - - - - - - Acetyltransf_1 k141_16788_3 223926.28808942 5.63e-90 272.0 COG1398@1|root,COG1398@2|Bacteria,1N2MA@1224|Proteobacteria,1RM88@1236|Gammaproteobacteria,1XSEJ@135623|Vibrionales 135623|Vibrionales I desaturase - - 1.14.19.1 ko:K00507 ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212 - R02222 RC00917 ko00000,ko00001,ko01000,ko01004 - - - FA_desaturase k141_214_1 1279017.AQYJ01000028_gene2075 1.1e-81 272.0 COG0457@1|root,COG0457@2|Bacteria,1MXSS@1224|Proteobacteria,1S157@1236|Gammaproteobacteria,467PR@72275|Alteromonadaceae 1236|Gammaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16,TPR_6 k141_214_2 1279017.AQYJ01000028_gene2074 2.81e-128 398.0 COG1729@1|root,COG1729@2|Bacteria,1MX82@1224|Proteobacteria,1T32S@1236|Gammaproteobacteria,465Q0@72275|Alteromonadaceae 1236|Gammaproteobacteria O protein conserved in bacteria - - - - - - - - - - - - TPR_16,TPR_6,TPR_8,YfiO k141_9640_1 1340493.JNIF01000004_gene801 3.75e-15 77.8 COG2006@1|root,COG2006@2|Bacteria 2|Bacteria U 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - - - - - - - - - - DUF362 k141_8502_2 1294265.JCM21738_1916 8.89e-41 139.0 COG2357@1|root,COG2357@2|Bacteria,1TQ2F@1239|Firmicutes,4HA3Q@91061|Bacilli,1ZBM8@1386|Bacillus 91061|Bacilli S GTP pyrophosphokinase yjbM GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5 ko:K07816 ko00230,map00230 - R00429 RC00002,RC00078 ko00000,ko00001,ko01000 - - - RelA_SpoT k141_20316_1 880073.Calab_1218 7.23e-12 63.2 COG0848@1|root,COG0848@2|Bacteria,2NQ52@2323|unclassified Bacteria 2|Bacteria U Biopolymer transport protein ExbD/TolR - - - ko:K03559 - - - - ko00000,ko02000 1.A.30.2.1 - - ExbD k141_20316_2 1125863.JAFN01000001_gene2657 8.63e-23 94.7 COG0811@1|root,COG0811@2|Bacteria,1QNJ1@1224|Proteobacteria,43BH1@68525|delta/epsilon subdivisions,2X6VI@28221|Deltaproteobacteria 28221|Deltaproteobacteria U MotA/TolQ/ExbB proton channel family - - - ko:K03561 - - - - ko00000,ko02000 1.A.30.2.1 - - MotA_ExbB k141_34635_1 565045.NOR51B_2831 2.88e-68 227.0 COG1629@1|root,COG4771@2|Bacteria,1MWKN@1224|Proteobacteria,1T3V3@1236|Gammaproteobacteria 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_31110_4 1116375.VEJY3_06845 6.78e-115 344.0 COG0559@1|root,COG0559@2|Bacteria,1MVND@1224|Proteobacteria,1RQXD@1236|Gammaproteobacteria,1XUB9@135623|Vibrionales 135623|Vibrionales E Belongs to the binding-protein-dependent transport system permease family urtB - - ko:K11960 ko02010,map02010 M00323 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4.4,3.A.1.4.5 - - BPD_transp_2 k141_16805_1 218284.CCDN010000007_gene3836 1.63e-123 365.0 COG1113@1|root,COG1113@2|Bacteria,1TP97@1239|Firmicutes,4H9QX@91061|Bacilli,1ZAQB@1386|Bacillus 91061|Bacilli E COG1113 Gamma-aminobutyrate permease and related permeases aapA - - ko:K03293,ko:K11737 - - - - ko00000,ko02000 2.A.3.1,2.A.3.1.7 - - AA_permease k141_36979_1 218284.CCDN010000004_gene3103 1.16e-193 544.0 COG2610@1|root,COG2610@2|Bacteria,1TQJ6@1239|Firmicutes,4HA01@91061|Bacilli,1ZCGI@1386|Bacillus 91061|Bacilli EG COG2610 H gluconate symporter and related permeases - - - - - - - - - - - - GntP_permease k141_22755_1 1279017.AQYJ01000028_gene2320 3.53e-217 624.0 COG0709@1|root,COG1252@1|root,COG0709@2|Bacteria,COG1252@2|Bacteria,1MWFG@1224|Proteobacteria,1RQ5Q@1236|Gammaproteobacteria,465WT@72275|Alteromonadaceae 1236|Gammaproteobacteria CE Belongs to the selenophosphate synthase 1 family. Class I subfamily - - 2.7.9.3 ko:K01008 ko00450,ko01100,map00450,map01100 - R03595 RC00002,RC02878 ko00000,ko00001,ko01000,ko03016 - - - AIRS,AIRS_C,Pyr_redox_2 k141_27474_1 1042377.AFPJ01000030_gene477 1.55e-38 134.0 COG2259@1|root,COG2259@2|Bacteria,1RBZP@1224|Proteobacteria,1S28E@1236|Gammaproteobacteria,466DA@72275|Alteromonadaceae 1236|Gammaproteobacteria S DoxX - - - ko:K15977 - - - - ko00000 - - - DoxX k141_8516_2 1132442.KB889752_gene760 1.57e-18 87.0 COG3334@1|root,COG3334@2|Bacteria,1V87H@1239|Firmicutes,4HM5Z@91061|Bacilli,1ZCXR@1386|Bacillus 91061|Bacilli S MgtE intracellular N domain ylxF - - - - - - - - - - - MgtE_N k141_8516_3 218284.CCDN010000001_gene1928 2.24e-75 228.0 COG2882@1|root,COG2882@2|Bacteria,1V6SQ@1239|Firmicutes,4HJZP@91061|Bacilli,1ZGXV@1386|Bacillus 91061|Bacilli N Flagellar biosynthesis chaperone fliJ GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02413 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FliJ k141_10822_2 218284.CCDN010000002_gene1986 1.09e-49 158.0 COG1828@1|root,COG1828@2|Bacteria,1VEH1@1239|Firmicutes,4HP0E@91061|Bacilli,1ZHUG@1386|Bacillus 91061|Bacilli F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL purS - 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU06460 PurS k141_26364_2 218284.CCDN010000004_gene3064 1.44e-38 130.0 29T6N@1|root,30EDD@2|Bacteria,1UCF1@1239|Firmicutes,4INXD@91061|Bacilli,1ZP2T@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_7305_1 1453501.JELR01000002_gene800 6.71e-55 181.0 COG1902@1|root,COG1902@2|Bacteria,1MVIX@1224|Proteobacteria,1RMFI@1236|Gammaproteobacteria,464MK@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family - - - - - - - - - - - - Oxidored_FMN k141_20329_2 1110502.TMO_0268 2.41e-42 145.0 COG1802@1|root,COG1802@2|Bacteria,1R5JG@1224|Proteobacteria,2U4YJ@28211|Alphaproteobacteria,2JT5V@204441|Rhodospirillales 204441|Rhodospirillales K FCD - - - - - - - - - - - - FCD,GntR k141_1309_1 1294265.JCM21738_4142 6.7e-123 360.0 COG3633@1|root,COG3633@2|Bacteria,1TPD2@1239|Firmicutes,4HBEC@91061|Bacilli,1ZC2H@1386|Bacillus 91061|Bacilli E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) sstT - - ko:K07862 - - - - ko00000,ko02000 2.A.23.4 - - SDF k141_12048_2 307480.IW16_02850 4.3e-84 269.0 COG0515@1|root,COG0515@2|Bacteria,4PBBS@976|Bacteroidetes,1IBKV@117743|Flavobacteriia 976|Bacteroidetes KLT serine threonine protein kinase - - - - - - - - - - - - - k141_35790_1 997296.PB1_01005 2.97e-67 217.0 COG2201@1|root,COG2201@2|Bacteria,1TRHC@1239|Firmicutes,4HBJY@91061|Bacilli,1ZC36@1386|Bacillus 91061|Bacilli NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR cheB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.1.1.61,3.5.1.44 ko:K03412 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 - - - CheB_methylest,Response_reg k141_25095_2 406124.ACPC01000008_gene1646 2.66e-254 706.0 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4HBS1@91061|Bacilli,1ZCI4@1386|Bacillus 91061|Bacilli C Belongs to the aldehyde dehydrogenase family. RocA subfamily rocA - 1.2.1.88 ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 - R00245,R00707,R00708,R04444,R04445,R05051 RC00080,RC00216,RC00242,RC00255 ko00000,ko00001,ko01000 - - - Aldedh k141_28747_2 556268.OFAG_00399 3.04e-20 84.0 2E7BZ@1|root,331V9@2|Bacteria,1N8MZ@1224|Proteobacteria,2W3YC@28216|Betaproteobacteria 28216|Betaproteobacteria S Domain of Unknown Function (DUF1540) - - - - - - - - - - - - DUF1540 k141_26365_1 1246484.D479_16097 1e-88 273.0 COG1232@1|root,COG1232@2|Bacteria,1TQ6W@1239|Firmicutes,4HAUG@91061|Bacilli,3ND3S@45667|Halobacillus 91061|Bacilli H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX hemY - 1.3.3.15,1.3.3.4 ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03222,R04178 RC00885 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS09325 Amino_oxidase k141_2575_2 218284.CCDN010000001_gene1048 9.6e-121 346.0 29419@1|root,2ZRG2@2|Bacteria,1V3UB@1239|Firmicutes,4HI22@91061|Bacilli,1ZC8M@1386|Bacillus 91061|Bacilli S Stage V sporulation protein AE spoVAEA - - ko:K06407 - - - - ko00000 - - - SpoVAE k141_34654_2 565045.NOR51B_1850 8.19e-21 90.5 COG0454@1|root,COG0456@2|Bacteria,1RIE6@1224|Proteobacteria,1S9G0@1236|Gammaproteobacteria,1J6ZE@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria K This enzyme acetylates the N-terminal alanine of ribosomal protein S18 rimI GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008999,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0017189,GO:0018193,GO:0018194,GO:0019538,GO:0031365,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564 2.3.1.128 ko:K03789 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_1 k141_34654_3 1453501.JELR01000001_gene3274 4.49e-88 270.0 2BZVX@1|root,32R5V@2|Bacteria,1RKXP@1224|Proteobacteria,1T470@1236|Gammaproteobacteria,468AV@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_27475_1 42565.FP66_08220 6.67e-121 354.0 COG0523@1|root,COG0523@2|Bacteria,1MVZV@1224|Proteobacteria,1RQDY@1236|Gammaproteobacteria,1XI09@135619|Oceanospirillales 135619|Oceanospirillales S Cobalamin synthesis protein P47K - - - - - - - - - - - - CobW_C,cobW k141_27475_2 42565.FP66_08225 1.9e-44 151.0 COG1469@1|root,COG1469@2|Bacteria,1MV1B@1224|Proteobacteria,1RNDY@1236|Gammaproteobacteria,1XJCU@135619|Oceanospirillales 135619|Oceanospirillales S Converts GTP to 7,8-dihydroneopterin triphosphate folE2 - 3.5.4.16 ko:K09007 ko00790,ko01100,map00790,map01100 M00126 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 - - - GCHY-1 k141_33420_1 218284.CCDN010000002_gene2554 2.21e-132 390.0 COG4533@1|root,COG4533@2|Bacteria,1TRY2@1239|Firmicutes,4HBZ3@91061|Bacilli,1ZAUC@1386|Bacillus 91061|Bacilli S Sugar transport-related sRNA regulator N-term - - - - - - - - - - - - SBP_bac_5,SgrR_N k141_7306_1 1121918.ARWE01000001_gene547 1.4e-84 265.0 COG1012@1|root,COG1012@2|Bacteria,1MY2V@1224|Proteobacteria,42Y54@68525|delta/epsilon subdivisions,2WTZ8@28221|Deltaproteobacteria 28221|Deltaproteobacteria C Aldehyde dehydrogenase family - - - - - - - - - - - - Aldedh k141_13272_1 218284.CCDN010000005_gene3168 1.53e-134 387.0 COG3481@1|root,COG3481@2|Bacteria,1TPIU@1239|Firmicutes,4HB1M@91061|Bacilli,1ZB1G@1386|Bacillus 91061|Bacilli L Shows a 3'-5' exoribonuclease activity yhaM GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031123,GO:0031125,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - ko:K03698 - - - - ko00000,ko01000,ko03019 - - - HD,tRNA_anti-codon k141_6181_1 218284.CCDN010000001_gene615 1.13e-118 346.0 COG2805@1|root,COG2805@2|Bacteria,1TQ5F@1239|Firmicutes,4H9RK@91061|Bacilli,1ZB6M@1386|Bacillus 91061|Bacilli NU twitching motility protein pilT - - ko:K02669 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE k141_21610_2 1279017.AQYJ01000028_gene2280 0.0 1088.0 COG1501@1|root,COG1501@2|Bacteria,1MWNJ@1224|Proteobacteria,1RMJ9@1236|Gammaproteobacteria,465UA@72275|Alteromonadaceae 1236|Gammaproteobacteria G Belongs to the glycosyl hydrolase 31 family malZ GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016758,GO:0033825,GO:0046527 2.4.1.161,3.2.1.177,3.2.1.20 ko:K01187,ko:K01811,ko:K18820 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00028,R00801,R00802,R06087,R06088 RC00028,RC00049,RC00077 ko00000,ko00001,ko01000 - GH31 - CBM_20,DUF4968,DUF5110,Gal_mutarotas_2,Glyco_hydro_31,PA14 k141_23913_2 218284.CCDN010000005_gene3348 8.99e-45 146.0 2EGG3@1|root,33A84@2|Bacteria,1VM9Y@1239|Firmicutes,4HR8J@91061|Bacilli,1ZJZJ@1386|Bacillus 91061|Bacilli S YueH-like protein yueH - - - - - - - - - - - YueH k141_19159_1 218284.CCDN010000001_gene99 5.52e-150 433.0 COG0439@1|root,COG0439@2|Bacteria,1TP16@1239|Firmicutes,4HA40@91061|Bacilli,1ZBTG@1386|Bacillus 91061|Bacilli I Biotin carboxylase accA1 - 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 k141_19159_2 1196031.ALEG01000039_gene1543 1.98e-28 103.0 COG1038@1|root,COG1038@2|Bacteria,1UIWR@1239|Firmicutes,4ISV0@91061|Bacilli,1ZS6P@1386|Bacillus 91061|Bacilli C Biotin carboxyl carrier protein yngHB - - ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742 RC00040,RC00367 ko00000,ko00001,ko00002 - - - Biotin_lipoyl k141_12049_2 550540.Fbal_2990 2.38e-28 102.0 2EA6R@1|root,334BH@2|Bacteria,1N9KD@1224|Proteobacteria,1SE14@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF3185) - - - - - - - - - - - - DUF3185 k141_18061_1 562743.JH976434_gene1018 9.59e-23 92.4 2CF44@1|root,34APP@2|Bacteria,1W0UZ@1239|Firmicutes,4HYRJ@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - k141_16806_1 95619.PM1_0202825 7.84e-22 98.2 COG1109@1|root,COG4191@1|root,COG1109@2|Bacteria,COG4191@2|Bacteria,1MUA5@1224|Proteobacteria,1RMU8@1236|Gammaproteobacteria 1236|Gammaproteobacteria G phosphomannomutase algC GO:0003674,GO:0003824,GO:0004615,GO:0005975,GO:0008150,GO:0008152,GO:0016853,GO:0016866,GO:0016868,GO:0044238,GO:0071704 5.4.2.2,5.4.2.8 ko:K15778 ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00114 R00959,R01057,R01818,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV k141_28748_1 218284.CCDN010000005_gene3495 1.84e-80 257.0 COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,1TPKU@1239|Firmicutes,4H9KR@91061|Bacilli,1ZAVB@1386|Bacillus 91061|Bacilli GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type) fruA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563 2.7.1.202 ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1 - - PTS_EIIA_2,PTS_EIIC,PTS_IIB k141_27476_1 218284.CCDN010000001_gene758 4.79e-43 147.0 COG1806@1|root,COG1806@2|Bacteria,1TPG0@1239|Firmicutes,4HB0Q@91061|Bacilli,1ZBIT@1386|Bacillus 91061|Bacilli S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation yqfL - 2.7.11.33,2.7.4.28 ko:K09773 - - - - ko00000,ko01000 - - - Kinase-PPPase k141_6182_1 218284.CCDN010000001_gene99 9.53e-98 296.0 COG0439@1|root,COG0439@2|Bacteria,1TP16@1239|Firmicutes,4HA40@91061|Bacilli,1ZBTG@1386|Bacillus 91061|Bacilli I Biotin carboxylase accA1 - 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 k141_3767_1 218284.CCDN010000001_gene1881 1.87e-61 199.0 COG0726@1|root,COG0726@2|Bacteria,1TQ5M@1239|Firmicutes,4HAHC@91061|Bacilli,1ZC6V@1386|Bacillus 91061|Bacilli G Sporulation protein, polysaccharide deacetylase ylxY GO:0005575,GO:0016020 - - - - - - - - - - Polysacc_deac_1 k141_26366_1 1461580.CCAS010000026_gene2607 8.51e-114 354.0 COG0847@1|root,COG1199@1|root,COG0847@2|Bacteria,COG1199@2|Bacteria,1TQHQ@1239|Firmicutes,4HB2Y@91061|Bacilli,1ZAWI@1386|Bacillus 91061|Bacilli L helicase involved in DNA repair and perhaps also replication dinG - 3.6.4.12 ko:K03722 - - - - ko00000,ko01000,ko03400 - - - DEAD,Helicase_C_2,RNase_T,ResIII k141_31113_2 1042377.AFPJ01000028_gene2191 2.44e-67 211.0 2ANPA@1|root,31DNS@2|Bacteria,1RHTE@1224|Proteobacteria,1S78C@1236|Gammaproteobacteria,467E1@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF3833) PP2730 - - - - - - - - - - - DUF3833 k141_36981_1 1294265.JCM21738_2140 1.94e-103 322.0 COG1523@1|root,COG1523@2|Bacteria,1TP3M@1239|Firmicutes,4HBP5@91061|Bacilli,1ZC85@1386|Bacillus 91061|Bacilli G Belongs to the glycosyl hydrolase 13 family pulA2 - 3.2.1.1,3.2.1.41 ko:K01176,ko:K01200 ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973 - R02108,R02111,R02112,R11262 - ko00000,ko00001,ko01000 - CBM48,GH13 - Alpha-amylase,Big_2,CBM_48,G5,Gram_pos_anchor,PUD,SLH,YSIRK_signal k141_36981_2 672.VV93_v1c20210 5.74e-20 88.2 COG0596@1|root,COG0596@2|Bacteria,1R53J@1224|Proteobacteria,1RXY0@1236|Gammaproteobacteria,1XV80@135623|Vibrionales 135623|Vibrionales S hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - - - - - - - - - - Abhydrolase_1 k141_2577_1 218284.CCDN010000001_gene79 1.27e-121 357.0 COG0849@1|root,COG0849@2|Bacteria,1TP1Z@1239|Firmicutes,4H9NF@91061|Bacilli,1ZBH1@1386|Bacillus 91061|Bacilli D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring ftsA GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032153,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0098552,GO:0098562 - ko:K03590 ko04112,map04112 - - - ko00000,ko00001,ko03036,ko04812 - - - DUF3484,FtsA,SHS2_FTSA k141_1312_1 935836.JAEL01000003_gene403 2.92e-29 114.0 COG0368@1|root,COG0368@2|Bacteria,1V0Q6@1239|Firmicutes,4HEUS@91061|Bacilli,1ZBU1@1386|Bacillus 91061|Bacilli H Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate cobS - 2.7.8.26 ko:K02233 ko00860,ko01100,map00860,map01100 M00122 R05223,R11174 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - CobS k141_18062_1 218284.CCDN010000004_gene3047 1.36e-90 267.0 COG1670@1|root,COG1670@2|Bacteria,1V3W1@1239|Firmicutes,4HH6A@91061|Bacilli,1ZG7V@1386|Bacillus 91061|Bacilli J Acetyltransferase (GNAT) domain speG - - - - - - - - - - - Acetyltransf_3 k141_6213_1 406124.ACPC01000019_gene3207 8.79e-22 90.5 COG2323@1|root,COG2323@2|Bacteria,1V3NW@1239|Firmicutes,4HHEY@91061|Bacilli,1ZDIR@1386|Bacillus 91061|Bacilli S membrane yrbG - - - - - - - - - - - DUF421 k141_25125_1 218284.CCDN010000002_gene2937 1.58e-135 383.0 COG3557@1|root,COG3557@2|Bacteria,1TRX8@1239|Firmicutes,4H9NM@91061|Bacilli,1ZB2J@1386|Bacillus 91061|Bacilli J Belongs to the UPF0374 family ygaC - - ko:K07586 - - - - ko00000 - - - DUF402 k141_9670_2 345219.Bcoa_2792 7.94e-48 160.0 COG0648@1|root,COG0648@2|Bacteria,1TP1D@1239|Firmicutes,4HB4F@91061|Bacilli,1ZBYQ@1386|Bacillus 91061|Bacilli L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin nfo GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.1.21.2 ko:K01151 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - AP_endonuc_2 k141_2589_2 1279017.AQYJ01000023_gene3271 1.31e-27 102.0 COG5591@1|root,COG5591@2|Bacteria,1N7TH@1224|Proteobacteria,1SF7U@1236|Gammaproteobacteria,46BWG@72275|Alteromonadaceae 1236|Gammaproteobacteria S Peptidase propeptide and YPEB domain - - - - - - - - - - - - PepSY_2 k141_22765_1 42565.FP66_09085 1.3e-97 286.0 COG2335@1|root,COG2335@2|Bacteria,1RD06@1224|Proteobacteria,1RSMY@1236|Gammaproteobacteria,1XKS0@135619|Oceanospirillales 135619|Oceanospirillales M Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - - - - - - - - - - Fasciclin k141_7331_1 743299.Acife_0649 1.11e-39 151.0 COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,1RN40@1236|Gammaproteobacteria,2NBQF@225057|Acidithiobacillales 225057|Acidithiobacillales C Xanthine dehydrogenase - - - - - - - - - - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 k141_26387_1 1294265.JCM21738_1360 2.4e-30 108.0 COG1051@1|root,COG1051@2|Bacteria 2|Bacteria F GDP-mannose mannosyl hydrolase activity - - 2.7.7.1,3.6.1.55 ko:K03207,ko:K03574,ko:K13522 ko00760,ko01100,map00760,map01100 - R00137,R03005 RC00002 ko00000,ko00001,ko01000,ko03400 - - - CTP_transf_like,NUDIX k141_26387_3 1294265.JCM21738_1358 8.29e-32 112.0 2CDZ2@1|root,32RYS@2|Bacteria,1VABM@1239|Firmicutes,4HKKB@91061|Bacilli,1ZHT7@1386|Bacillus 91061|Bacilli S Putative membrane protein yuiB - - - - - - - - - - - YuiB k141_6214_1 1196031.ALEG01000041_gene2465 1.48e-89 264.0 COG2318@1|root,COG2318@2|Bacteria,1V95A@1239|Firmicutes,4IDNB@91061|Bacilli,1ZCII@1386|Bacillus 91061|Bacilli S DinB superfamily - - - - - - - - - - - - DinB_2 k141_12079_8 698769.JFBD01000002_gene2747 4.31e-25 97.4 COG2963@1|root,COG2963@2|Bacteria,1V6XW@1239|Firmicutes,4HIUS@91061|Bacilli 91061|Bacilli L transposase activity - - - - - - - - - - - - HTH_23 k141_15680_2 218284.CCDN010000001_gene1287 1.16e-121 354.0 COG0159@1|root,COG0159@2|Bacteria,1TPXA@1239|Firmicutes,4HFQ8@91061|Bacilli,1ZC5U@1386|Bacillus 91061|Bacilli E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate trpA - 4.2.1.20 ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - Trp_syntA k141_20340_1 997296.PB1_17209 7.97e-67 219.0 COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,4H9RY@91061|Bacilli,1ZBR9@1386|Bacillus 91061|Bacilli S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid ytgP GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03328 - - - - ko00000 2.A.66.2 - - Polysacc_synt,Polysacc_synt_C k141_25346_1 388399.SSE37_20477 1.14e-45 160.0 COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,2TR1D@28211|Alphaproteobacteria 28211|Alphaproteobacteria E ABC-type dipeptide transport system periplasmic component - - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 k141_25346_2 1415756.JQMY01000001_gene720 4.51e-22 90.9 COG3342@1|root,COG3342@2|Bacteria,1MWQT@1224|Proteobacteria,2TRJZ@28211|Alphaproteobacteria,2PE4Q@252301|Oceanicola 28211|Alphaproteobacteria S Family of unknown function (DUF1028) - - - - - - - - - - - - DUF1028 k141_12372_1 90371.CY43_00170 3.98e-14 71.2 28ICJ@1|root,2Z8EW@2|Bacteria,1R61P@1224|Proteobacteria,1S0BB@1236|Gammaproteobacteria,3ZKC8@590|Salmonella 1236|Gammaproteobacteria S Nucleoside-specific channel-forming protein, Tsx - - - - - - - - - - - - Channel_Tsx k141_12372_2 1116375.VEJY3_21386 1.23e-52 169.0 COG2249@1|root,COG2249@2|Bacteria,1R49E@1224|Proteobacteria,1RZBC@1236|Gammaproteobacteria 1236|Gammaproteobacteria S NADPH-quinone reductase (modulator of drug activity B) - - - ko:K11746 - - - - ko00000,ko02000 2.A.37.1.1 - - Flavodoxin_2 k141_476_1 1042377.AFPJ01000020_gene2099 4.33e-145 419.0 COG0715@1|root,COG0715@2|Bacteria,1MWDN@1224|Proteobacteria,1RPUP@1236|Gammaproteobacteria,465AR@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components nrtC - - ko:K15576 ko00910,ko02010,map00910,map02010 M00438 - - ko00000,ko00001,ko00002,ko02000 3.A.1.16.1,3.A.1.16.2 - - NMT1_2 k141_9901_2 768671.ThimaDRAFT_4173 4.86e-75 233.0 COG1355@1|root,COG1355@2|Bacteria,1MXK5@1224|Proteobacteria,1RQPK@1236|Gammaproteobacteria,1WX63@135613|Chromatiales 135613|Chromatiales S Belongs to the MEMO1 family - - - ko:K06990 - - - - ko00000,ko04812 - - - Memo k141_7460_1 218284.CCDN010000007_gene3888 4.32e-91 269.0 COG0477@1|root,COG2814@2|Bacteria,1TRVP@1239|Firmicutes,4IQRS@91061|Bacilli,1ZRN2@1386|Bacillus 91061|Bacilli EGP Major Facilitator Superfamily - - - ko:K08168 - M00704 - - ko00000,ko00002,ko01504,ko02000 2.A.1.3.16,2.A.1.3.22,2.A.1.3.6 - - MFS_1,Sugar_tr k141_26714_1 218284.CCDN010000007_gene3938 1.35e-118 345.0 2C8MW@1|root,2ZCFU@2|Bacteria,1V10H@1239|Firmicutes,4HE3P@91061|Bacilli,1ZCQG@1386|Bacillus 91061|Bacilli S Transcriptional regulator rsfA - - ko:K06314 - - - - ko00000,ko03000 - - - Myb_DNA-bind_6 k141_23019_2 1279017.AQYJ01000024_gene1083 8.46e-227 637.0 COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,1RMGD@1236|Gammaproteobacteria,464UU@72275|Alteromonadaceae 1236|Gammaproteobacteria M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein murF GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008766,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0047480,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 - R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - iB21_1397.B21_00086,iEC042_1314.EC042_0087,iEC55989_1330.EC55989_0082,iECBD_1354.ECBD_3531,iECB_1328.ECB_00087,iECD_1391.ECD_00087,iECIAI1_1343.ECIAI1_0085,iECO103_1326.ECO103_0088,iECO111_1330.ECO111_0089,iECO26_1355.ECO26_0089,iECSE_1348.ECSE_0088,iECW_1372.ECW_m0085,iEKO11_1354.EKO11_3828,iEcE24377_1341.EcE24377A_0088,iEcHS_1320.EcHS_A0092,iEcolC_1368.EcolC_3571,iSBO_1134.SBO_0074,iSSON_1240.SSON_0094,iSbBS512_1146.SbBS512_E0079,iUMNK88_1353.UMNK88_86,iWFL_1372.ECW_m0085,iYL1228.KPN_00090 Mur_ligase,Mur_ligase_C,Mur_ligase_M k141_23019_3 1279017.AQYJ01000024_gene1082 8.37e-282 780.0 COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,1RMD6@1236|Gammaproteobacteria,465IN@72275|Alteromonadaceae 1236|Gammaproteobacteria M acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan murE GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 ko:K01928 ko00300,ko00550,map00300,map00550 - R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 - - iECO103_1326.ECO103_0087,iECO111_1330.ECO111_0088,iECW_1372.ECW_m0084,iEKO11_1354.EKO11_3829,iWFL_1372.ECW_m0084,ic_1306.c0103 Mur_ligase,Mur_ligase_C,Mur_ligase_M k141_23019_5 1453501.JELR01000001_gene3052 2.08e-28 105.0 COG3116@1|root,COG3116@2|Bacteria 2|Bacteria D cell division ftsL GO:0000003,GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0019954,GO:0022402,GO:0022414,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0043093,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944 - ko:K03586 - - - - ko00000,ko03036 - - - FtsL k141_21779_1 674977.VMC_40220 2.57e-89 269.0 COG1940@1|root,COG1940@2|Bacteria,1MU94@1224|Proteobacteria,1RNHE@1236|Gammaproteobacteria,1XSU2@135623|Vibrionales 135623|Vibrionales F Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P nagK - 2.7.1.59 ko:K00884 ko00520,ko01100,map00520,map01100 - R01201 RC00002,RC00017 ko00000,ko00001,ko01000 - - - ROK k141_8732_2 218284.CCDN010000001_gene1273 1.05e-59 201.0 COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,1TSAC@1239|Firmicutes,4HAJG@91061|Bacilli,1ZB2G@1386|Bacillus 91061|Bacilli L ATP-dependent DNA ligase ligD - 6.5.1.1 ko:K01971 ko03450,map03450 - R00381 RC00005 ko00000,ko00001,ko01000,ko03400 - - - DNA_ligase_A_M k141_12373_1 1027292.HMPREF9372_2688 6.16e-60 189.0 COG0386@1|root,COG0386@2|Bacteria,1V3M3@1239|Firmicutes,4HH5Q@91061|Bacilli,26F3U@186818|Planococcaceae 91061|Bacilli O Belongs to the glutathione peroxidase family bsaA - 1.11.1.9 ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 - R00274,R07034,R07035 RC00011,RC00982 ko00000,ko00001,ko01000 - - - GSHPx k141_13542_1 1121920.AUAU01000004_gene625 7.08e-47 164.0 COG0321@1|root,COG1051@1|root,COG0321@2|Bacteria,COG1051@2|Bacteria,3Y448@57723|Acidobacteria 57723|Acidobacteria H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate lipB - 2.3.1.181 ko:K03801 ko00785,ko01100,map00785,map01100 - R07766,R07769 RC00039,RC00992,RC02867 ko00000,ko00001,ko01000 - - - BPL_LplA_LipB,NUDIX k141_6429_1 1294265.JCM21738_5090 2.4e-24 97.1 2DB72@1|root,2Z7JI@2|Bacteria,1UR4B@1239|Firmicutes,4HCE4@91061|Bacilli,1ZC8T@1386|Bacillus 91061|Bacilli S Putative amidase domain yhbB - - - - - - - - - - - Amidase_6 k141_6429_2 471223.GWCH70_0503 2.72e-26 106.0 COG1600@1|root,COG1600@2|Bacteria,1TP6Q@1239|Firmicutes,4HAEW@91061|Bacilli,1WFHI@129337|Geobacillus 91061|Bacilli C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) queG GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 ko:K18979 - - - - ko00000,ko01000,ko03016 - - - DUF1730,Fer4_16,HEAT_2 k141_1513_1 1255043.TVNIR_1411 5.89e-68 214.0 COG2738@1|root,COG2738@2|Bacteria,1RDJH@1224|Proteobacteria,1S4QY@1236|Gammaproteobacteria,1X0PS@135613|Chromatiales 135613|Chromatiales S Putative neutral zinc metallopeptidase - - - ko:K06973 - - - - ko00000 - - - Zn_peptidase_2 k141_17010_1 1116375.VEJY3_17996 1.46e-123 360.0 COG0583@1|root,COG0583@2|Bacteria,1N4BZ@1224|Proteobacteria,1RRCD@1236|Gammaproteobacteria,1XUB7@135623|Vibrionales 135623|Vibrionales K COG0583 Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_4035_1 218284.CCDN010000001_gene710 2.29e-67 208.0 COG1183@1|root,COG1183@2|Bacteria,1TR44@1239|Firmicutes,4HFUP@91061|Bacilli,1ZC3H@1386|Bacillus 91061|Bacilli I Belongs to the CDP-alcohol phosphatidyltransferase class-I family pssA - 2.7.8.8 ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 M00093 R01800 RC00002,RC00017,RC02795 ko00000,ko00001,ko00002,ko01000 - - - CDP-OH_P_transf k141_18249_1 1453501.JELR01000002_gene874 3.97e-40 138.0 COG3247@1|root,COG3247@2|Bacteria,1RH69@1224|Proteobacteria,1SAIB@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Short repeat of unknown function (DUF308) - - - - - - - - - - - - DUF308 k141_18249_2 1453501.JELR01000002_gene1384 4.48e-26 103.0 COG0657@1|root,COG0657@2|Bacteria,1RD8A@1224|Proteobacteria,1S3TH@1236|Gammaproteobacteria,4687P@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG0657 Esterase lipase - - 3.1.1.83,3.1.1.85 ko:K14731,ko:K19561 ko00780,ko00903,ko00930,ko01100,ko01220,map00780,map00903,map00930,map01100,map01220 M00572 R03751,R06390,R06391,R06392,R06393,R09725 RC00460,RC00461,RC00713,RC00983,RC01505 ko00000,ko00001,ko00002,ko01000 - - - Abhydrolase_3 k141_7461_2 338963.Pcar_3002 6.94e-30 118.0 COG0845@1|root,COG0845@2|Bacteria,1R443@1224|Proteobacteria,43A2V@68525|delta/epsilon subdivisions,2X238@28221|Deltaproteobacteria,43VF8@69541|Desulfuromonadales 28221|Deltaproteobacteria M Biotin-lipoyl like - - - - - - - - - - - - HlyD_D23 k141_4036_1 338966.Ppro_3294 8.48e-42 154.0 COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,42NKY@68525|delta/epsilon subdivisions,2WJJG@28221|Deltaproteobacteria,43T9W@69541|Desulfuromonadales 28221|Deltaproteobacteria M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan murE GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 ko:K01928 ko00300,ko00550,map00300,map00550 - R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M k141_9904_1 203122.Sde_0425 1.98e-51 174.0 COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,1RMSS@1236|Gammaproteobacteria,4651Y@72275|Alteromonadaceae 1236|Gammaproteobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_int_SAM_4,Phage_integrase k141_29993_1 1121087.AUCK01000002_gene2460 7.89e-33 124.0 2C9JF@1|root,32RPD@2|Bacteria,1VC16@1239|Firmicutes,4IFWB@91061|Bacilli,1ZK9E@1386|Bacillus 91061|Bacilli S ERF superfamily - - - - - - - - - - - - ERF k141_12374_1 218284.CCDN010000005_gene3205 8.68e-140 409.0 COG3290@1|root,COG3290@2|Bacteria,1TQJR@1239|Firmicutes,4H9Q0@91061|Bacilli,1ZBHV@1386|Bacillus 91061|Bacilli T Signal transduction histidine kinase regulating citrate malate metabolism malK - 2.7.13.3 ko:K11614 ko02020,map02020 M00490 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,PAS,SPOB_a,sCache_3_2 k141_14601_2 223926.28809536 3.88e-71 225.0 COG1914@1|root,COG1914@2|Bacteria,1P45T@1224|Proteobacteria,1RPT0@1236|Gammaproteobacteria,1XUAT@135623|Vibrionales 135623|Vibrionales P Natural resistance-associated macrophage protein - - - - - - - - - - - - Nramp k141_28921_1 218284.CCDN010000002_gene2025 7.56e-157 447.0 COG2162@1|root,COG2162@2|Bacteria,1VA4Y@1239|Firmicutes,4HKYP@91061|Bacilli,1ZGW6@1386|Bacillus 91061|Bacilli Q N-acetyltransferase - - - - - - - - - - - - Acetyltransf_2 k141_24118_1 1122169.AREN01000004_gene426 1.43e-175 501.0 28JVF@1|root,2Z9KD@2|Bacteria,1MXZ6@1224|Proteobacteria,1RY7E@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_23021_2 218284.CCDN010000001_gene1727 1.07e-27 103.0 COG3216@1|root,COG3216@2|Bacteria,1VG1Z@1239|Firmicutes,4HQ47@91061|Bacilli,1ZHV3@1386|Bacillus 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2062) - - - ko:K09928 - - - - ko00000 - - - DUF2062 k141_480_1 218284.CCDN010000001_gene1006 3.42e-111 321.0 COG1878@1|root,COG1878@2|Bacteria,1UFUJ@1239|Firmicutes,4HD9U@91061|Bacilli,1ZQPZ@1386|Bacillus 91061|Bacilli S Putative cyclase - - 3.5.1.9 ko:K07130 ko00380,ko00630,ko01100,map00380,map00630,map01100 M00038 R00988,R01959,R04911 RC00263,RC00323 ko00000,ko00001,ko00002,ko01000 - - - Cyclase k141_26717_1 1294265.JCM21738_4876 6.12e-120 345.0 COG4123@1|root,COG4123@2|Bacteria,1TQ25@1239|Firmicutes,4HA8W@91061|Bacilli,1ZCBX@1386|Bacillus 91061|Bacilli S Conserved hypothetical protein 95 yabB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.223 ko:K07461,ko:K15460 - - - - ko00000,ko01000,ko03016 - - - GIY-YIG,MTS k141_13544_1 218284.CCDN010000001_gene1798 2.12e-181 513.0 COG2262@1|root,COG2262@2|Bacteria,1TNZB@1239|Firmicutes,4HACA@91061|Bacilli,1ZBT6@1386|Bacillus 91061|Bacilli S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis hflX - - ko:K03665 - - - - ko00000,ko03009 - - - GTP-bdg_M,GTP-bdg_N,MMR_HSR1 k141_2755_1 1042377.AFPJ01000028_gene2212 3.64e-78 251.0 COG4990@1|root,COG4990@2|Bacteria,1NU3R@1224|Proteobacteria,1SN0P@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Peptidase_C39 like family - - - - - - - - - - - - Peptidase_C39_2 k141_2755_2 1042377.AFPJ01000036_gene1130 1.62e-174 493.0 COG3023@1|root,COG3023@2|Bacteria,1RDHU@1224|Proteobacteria,1RMDN@1236|Gammaproteobacteria,46BUP@72275|Alteromonadaceae 1236|Gammaproteobacteria V N-acetylmuramoyl-L-alanine amidase amiD_2 - 3.4.16.4,3.5.1.28 ko:K01447,ko:K21469 ko00550,map00550 - R04112 RC00064,RC00141 ko00000,ko00001,ko01000,ko01002,ko01011 - - - Amidase_2,Beta-lactamase,PG_binding_1,SH3_3 k141_2755_3 1042377.AFPJ01000036_gene1131 1.97e-90 268.0 COG0791@1|root,COG0791@2|Bacteria,1NUXJ@1224|Proteobacteria,1SNKX@1236|Gammaproteobacteria 1236|Gammaproteobacteria M NlpC/P60 family - - - ko:K13695 - - - - ko00000,ko01002 - - - NLPC_P60 k141_2755_4 1042377.AFPJ01000036_gene1132 5.49e-294 830.0 COG0308@1|root,COG0308@2|Bacteria,1MUV3@1224|Proteobacteria,1RS0E@1236|Gammaproteobacteria,4666I@72275|Alteromonadaceae 1236|Gammaproteobacteria E Peptidase family M1 domain - - - - - - - - - - - - Peptidase_M1 k141_2755_5 1117647.M5M_07715 2.29e-142 417.0 COG0477@1|root,COG2814@2|Bacteria,1QKNX@1224|Proteobacteria,1RSAI@1236|Gammaproteobacteria 1236|Gammaproteobacteria EGP Major Facilitator - - - - - - - - - - - - MFS_1 k141_2755_6 1042377.AFPJ01000036_gene1138 2.19e-223 628.0 COG0791@1|root,COG0791@2|Bacteria,1R45H@1224|Proteobacteria,1RZDR@1236|Gammaproteobacteria,4668V@72275|Alteromonadaceae 1236|Gammaproteobacteria M SH3 domain (SH3b1 type) - - - - - - - - - - - - NLPC_P60,N_NLPC_P60,SH3_6,SH3_7 k141_2755_7 1042377.AFPJ01000036_gene1139 1.22e-223 621.0 COG4948@1|root,COG4948@2|Bacteria,1MU8R@1224|Proteobacteria,1RNM4@1236|Gammaproteobacteria,469H2@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily ykfB GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564 5.1.1.20 ko:K19802 - - R10938 RC03309 ko00000,ko01000 - - - MR_MLE_C,MR_MLE_N k141_2755_8 1042377.AFPJ01000036_gene1140 4.58e-134 385.0 COG1737@1|root,COG1737@2|Bacteria,1ND5W@1224|Proteobacteria,1RNCI@1236|Gammaproteobacteria,46B7G@72275|Alteromonadaceae 1236|Gammaproteobacteria K Helix-turn-helix domain, rpiR family yfhH GO:0003674,GO:0003700,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K15835 - - - - ko00000,ko03000 - - - HTH_6,SIS k141_2755_9 1042377.AFPJ01000036_gene1141 3.84e-225 632.0 COG1305@1|root,COG1305@2|Bacteria,1R72E@1224|Proteobacteria,1S1BR@1236|Gammaproteobacteria 1236|Gammaproteobacteria E COG1305 Transglutaminase-like enzymes - - - - - - - - - - - - Transglut_core k141_2755_10 1042377.AFPJ01000036_gene1142 3.12e-273 761.0 COG1680@1|root,COG1680@2|Bacteria,1MVZN@1224|Proteobacteria,1RP0R@1236|Gammaproteobacteria,468BI@72275|Alteromonadaceae 1236|Gammaproteobacteria V Beta-lactamase - - - - - - - - - - - - Beta-lactamase,DUF3471 k141_2755_11 1042377.AFPJ01000036_gene1143 2.18e-170 483.0 COG1619@1|root,COG1619@2|Bacteria,1MWIY@1224|Proteobacteria,1RQT8@1236|Gammaproteobacteria,466EE@72275|Alteromonadaceae 1236|Gammaproteobacteria V LD-carboxypeptidase ldcA GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009050,GO:0009056,GO:0009254,GO:0009987,GO:0016787,GO:0019538,GO:0030203,GO:0034641,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 3.4.17.13 ko:K01297 - - - - ko00000,ko01000,ko01002,ko01011 - - iAPECO1_1312.APECO1_304,iECABU_c1320.ECABU_c14580,iECED1_1282.ECED1_1334,iECOK1_1307.ECOK1_1338,iECS88_1305.ECS88_1255,iLF82_1304.LF82_1171,iNRG857_1313.NRG857_06085,iSFV_1184.SFV_1201,iSFxv_1172.SFxv_1357,iS_1188.S1271,iUMN146_1321.UM146_11125,iUTI89_1310.UTI89_C1378,ic_1306.c1641 Peptidase_S66 k141_2755_12 1042377.AFPJ01000036_gene1144 6.51e-282 776.0 COG1757@1|root,COG1757@2|Bacteria,1MY5C@1224|Proteobacteria,1RP6I@1236|Gammaproteobacteria,465EF@72275|Alteromonadaceae 1236|Gammaproteobacteria C Na H antiporter mleN - - - - - - - - - - - Na_H_antiporter k141_19410_1 1116375.VEJY3_01955 2.34e-212 590.0 COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,1XTPV@135623|Vibrionales 135623|Vibrionales O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain degS - - ko:K04691 - - - - ko00000,ko01000,ko01002 - - - PDZ_2,Trypsin_2 k141_19410_2 1116375.VEJY3_01950 0.0 1450.0 COG0188@1|root,COG0188@2|Bacteria,1MURI@1224|Proteobacteria,1RMTC@1236|Gammaproteobacteria,1XSUU@135623|Vibrionales 135623|Vibrionales L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parC - - ko:K02621 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseA_C,DNA_topoisoIV k141_19410_3 1280001.BAOA01000021_gene888 0.0 1243.0 COG0187@1|root,COG0187@2|Bacteria,1MVH1@1224|Proteobacteria,1RMCI@1236|Gammaproteobacteria,1XT02@135623|Vibrionales 135623|Vibrionales L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parE - - ko:K02622 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim k141_19410_4 223926.28805412 4.22e-124 355.0 COG3150@1|root,COG3150@2|Bacteria,1MVJF@1224|Proteobacteria,1S5WF@1236|Gammaproteobacteria,1XTCB@135623|Vibrionales 135623|Vibrionales S esterase yqiA - - ko:K07000 - - - - ko00000 - - - UPF0227 k141_18280_1 218284.CCDN010000002_gene2259 1.41e-195 549.0 COG0387@1|root,COG0387@2|Bacteria,1TQN2@1239|Firmicutes,4HB3X@91061|Bacilli,1ZC9V@1386|Bacillus 91061|Bacilli P COG0387 Ca2 H antiporter cax GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015085,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015368,GO:0015369,GO:0015491,GO:0015672,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051139,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:0099516,GO:1902600 - ko:K07300 - - - - ko00000,ko02000 2.A.19 - - Na_Ca_ex k141_17035_1 1294265.JCM21738_1388 8.43e-54 177.0 COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,4HAB3@91061|Bacilli,1ZAPP@1386|Bacillus 91061|Bacilli JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity - - - - - - - - - - - - DEAD,Helicase_C k141_4047_1 1078085.HMPREF1210_00665 5.46e-82 271.0 COG1409@1|root,COG4632@1|root,COG1409@2|Bacteria,COG4632@2|Bacteria,1UWQ2@1239|Firmicutes,4I2G2@91061|Bacilli,26G7J@186818|Planococcaceae 91061|Bacilli G Purple acid Phosphatase, N-terminal domain - - - - - - - - - - - - Metallophos,Pur_ac_phosph_N k141_24129_1 1453501.JELR01000002_gene1049 2.16e-243 683.0 COG2234@1|root,COG2234@2|Bacteria,1MUZ7@1224|Proteobacteria,1RS0Q@1236|Gammaproteobacteria,4653N@72275|Alteromonadaceae 1236|Gammaproteobacteria S PA domain - - - - - - - - - - - - PA,Peptidase_M28 k141_24129_2 1453501.JELR01000002_gene1048 1.31e-171 489.0 COG0454@1|root,COG0456@2|Bacteria,1MVZ2@1224|Proteobacteria,1RSC5@1236|Gammaproteobacteria,465P6@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG0456 Acetyltransferases - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10,DUF3335 k141_24129_3 1453501.JELR01000002_gene1033 1.62e-290 801.0 COG0189@1|root,COG0189@2|Bacteria,1MX5X@1224|Proteobacteria,1RNXP@1236|Gammaproteobacteria,464RX@72275|Alteromonadaceae 1236|Gammaproteobacteria HJ Glutathione synthase ribosomal protein S6 modification enzyme (Glutaminyl transferase) - - - - - - - - - - - - Dala_Dala_lig_C,RLAN,RimK k141_24129_6 1453501.JELR01000002_gene1031 5.62e-177 494.0 COG0543@1|root,COG0543@2|Bacteria,1QTSK@1224|Proteobacteria,1T1MX@1236|Gammaproteobacteria,46574@72275|Alteromonadaceae 1236|Gammaproteobacteria CH COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 fpr - 1.18.1.2,1.19.1.1 ko:K00528 - - R10159 - ko00000,ko01000 - - - FAD_binding_6,NAD_binding_1 k141_24129_7 715451.ambt_19715 4.57e-70 217.0 COG3040@1|root,COG3040@2|Bacteria,1RDAI@1224|Proteobacteria,1S3PW@1236|Gammaproteobacteria,466RV@72275|Alteromonadaceae 1236|Gammaproteobacteria M lipocalin blc GO:0005575,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0033554,GO:0044462,GO:0044464,GO:0050896,GO:0051716,GO:0071944 - ko:K03098 - - - - ko00000,ko04147 - - - Lipocalin_2 k141_24129_8 1279017.AQYJ01000027_gene1720 1.63e-87 282.0 28HMG@1|root,2Z7W1@2|Bacteria,1NPZ0@1224|Proteobacteria,1SH34@1236|Gammaproteobacteria,46C4A@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_35970_1 1384057.CD33_00520 2.87e-32 116.0 COG1335@1|root,COG1335@2|Bacteria,1V70H@1239|Firmicutes,4HJXC@91061|Bacilli 91061|Bacilli Q isochorismatase yrdC - - - - - - - - - - - Isochorismatase k141_20542_1 1294265.JCM21738_4233 1.56e-233 645.0 COG2404@1|root,COG2404@2|Bacteria,1TQPZ@1239|Firmicutes,4HCSM@91061|Bacilli,1ZCH8@1386|Bacillus 91061|Bacilli S phosphohydrolase (DHH superfamily) yngD - - ko:K07097 - - - - ko00000 - - - DHHA1 k141_502_1 218284.CCDN010000001_gene1822 9.55e-157 451.0 COG1966@1|root,COG1966@2|Bacteria,1TQN8@1239|Firmicutes,4H9SU@91061|Bacilli,1ZC6K@1386|Bacillus 91061|Bacilli T Carbon starvation protein cstA_2 - - - - - - - - - - - CstA,CstA_5TM k141_34837_2 644281.MFS40622_0774 6.49e-13 64.7 arCOG13418@1|root,arCOG13418@2157|Archaea,2Y5VK@28890|Euryarchaeota 28890|Euryarchaeota - - - - - - - - - - - - - - - k141_18281_1 997296.PB1_01075 3.18e-75 241.0 COG1749@1|root,COG1749@2|Bacteria,1UHS7@1239|Firmicutes,4IS7Y@91061|Bacilli,1ZS24@1386|Bacillus 91061|Bacilli N flagellar flgE - - ko:K02390 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FlaE,Flg_bb_rod,Flg_bbr_C k141_5144_1 1453501.JELR01000001_gene1956 1.02e-83 260.0 COG0460@1|root,COG0460@2|Bacteria,1MUDC@1224|Proteobacteria,1RPEU@1236|Gammaproteobacteria,463Y5@72275|Alteromonadaceae 1236|Gammaproteobacteria E homoserine dehydrogenase hom - 1.1.1.3,2.7.2.4 ko:K00003,ko:K12524 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00017,M00018,M00526,M00527 R00480,R01773,R01775 RC00002,RC00043,RC00087 ko00000,ko00001,ko00002,ko01000 - - - ACT,Homoserine_dh,NAD_binding_3 k141_27610_1 1453501.JELR01000002_gene1513 4.49e-62 207.0 COG1273@1|root,COG1273@2|Bacteria,1MWCU@1224|Proteobacteria,1RYQ0@1236|Gammaproteobacteria,46705@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF3426) - - - - - - - - - - - - DUF3426,zinc_ribbon_4,zinc_ribbon_5 k141_503_1 218284.CCDN010000007_gene3827 7.38e-48 167.0 COG4863@1|root,COG4863@2|Bacteria,1UV48@1239|Firmicutes,4HF30@91061|Bacilli,1ZD30@1386|Bacillus 91061|Bacilli S protein conserved in bacteria yycH - - - - - - - - - - - YycH k141_19412_1 1042377.AFPJ01000008_gene2002 2.66e-25 101.0 COG0119@1|root,COG0119@2|Bacteria,1MUMX@1224|Proteobacteria,1RMUX@1236|Gammaproteobacteria,469DW@72275|Alteromonadaceae 1236|Gammaproteobacteria E HMGL-like - - 4.1.3.4 ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 M00036,M00088 R01360,R08090 RC00502,RC00503,RC01118,RC01946 ko00000,ko00001,ko00002,ko01000 - - - HMGL-like k141_15837_1 243277.VC_0183 7.27e-115 348.0 COG0582@1|root,COG0582@2|Bacteria,1R9JZ@1224|Proteobacteria,1RY18@1236|Gammaproteobacteria,1XW77@135623|Vibrionales 135623|Vibrionales L viral genome integration into host DNA - - - - - - - - - - - - - k141_15837_2 55601.VANGNB10_cI2606 7.33e-97 296.0 COG0582@1|root,COG0582@2|Bacteria,1R5D1@1224|Proteobacteria,1S1EP@1236|Gammaproteobacteria,1XUYK@135623|Vibrionales 135623|Vibrionales L viral genome integration into host DNA - - - - - - - - - - - - - k141_13587_2 1042377.AFPJ01000030_gene508 3.63e-192 546.0 COG0226@1|root,COG2885@1|root,COG0226@2|Bacteria,COG2885@2|Bacteria,1MVXP@1224|Proteobacteria,1RNK7@1236|Gammaproteobacteria,46D11@72275|Alteromonadaceae 1236|Gammaproteobacteria MP PBP superfamily domain pstS - - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - OmpA,PBP_like_2 k141_24131_1 1002809.SSIL_1645 1.36e-24 102.0 COG3751@1|root,COG3751@2|Bacteria,1UNHV@1239|Firmicutes,4HEJV@91061|Bacilli,26F10@186818|Planococcaceae 91061|Bacilli O Prolyl 4-hydroxylase alpha subunit homologues. - - 1.14.11.2 ko:K00472 ko00330,ko01100,map00330,map01100 - R01252 RC00478 ko00000,ko00001,ko01000 - - - 2OG-FeII_Oxy_3 k141_30016_1 1121875.KB907553_gene20 1.23e-40 146.0 COG5361@1|root,COG5361@2|Bacteria,4NKSK@976|Bacteroidetes,1IARY@117743|Flavobacteriia 976|Bacteroidetes S Protein of unknown function (DUF1254) - - - - - - - - - - - - DUF1214,DUF1254 k141_30016_2 1042377.AFPJ01000016_gene114 8.22e-38 131.0 COG2353@1|root,COG2353@2|Bacteria,1MZDI@1224|Proteobacteria,1S9EZ@1236|Gammaproteobacteria,467TE@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the UPF0312 family - - - - - - - - - - - - YceI k141_12399_1 218284.CCDN010000007_gene3894 1.19e-62 196.0 COG2318@1|root,COG2318@2|Bacteria,1V9Q2@1239|Firmicutes,4HIHF@91061|Bacilli,1ZRZT@1386|Bacillus 91061|Bacilli S DinB superfamily - - - - - - - - - - - - DinB_2 k141_12399_3 1121090.KB894685_gene3461 1.85e-47 166.0 COG0665@1|root,COG0723@1|root,COG0665@2|Bacteria,COG0723@2|Bacteria,1TR1R@1239|Firmicutes,4H9V8@91061|Bacilli,1ZC19@1386|Bacillus 91061|Bacilli CE COG0665 Glycine D-amino acid oxidases (deaminating) yhfW GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0044424,GO:0044464,GO:0055114 - - - - - - - - - - DAO,Rieske k141_20544_1 1294265.JCM21738_4670 1.05e-109 324.0 COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,4HA13@91061|Bacilli,1ZAWQ@1386|Bacillus 91061|Bacilli E Aminotransferase patA - - ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 M00525 R04467 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k141_26741_1 765914.ThisiDRAFT_0008 6.25e-13 67.8 COG2927@1|root,COG2927@2|Bacteria 2|Bacteria L positive regulation of DNA-dependent DNA replication initiation holC GO:0005575,GO:0005622,GO:0005623,GO:0006275,GO:0008150,GO:0009314,GO:0009360,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010556,GO:0010557,GO:0010604,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032298,GO:0032991,GO:0042575,GO:0043846,GO:0043847,GO:0044424,GO:0044464,GO:0045740,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051054,GO:0051171,GO:0051173,GO:0060255,GO:0061695,GO:0065007,GO:0080090,GO:0090329,GO:1902494,GO:1990234,GO:2000105,GO:2000112 2.7.7.7 ko:K02339 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_chi k141_26741_2 1279017.AQYJ01000023_gene3189 7.1e-36 137.0 2EPR3@1|root,33HBJ@2|Bacteria,1NH9J@1224|Proteobacteria,1SHY3@1236|Gammaproteobacteria,4699X@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_12618_4 674977.VMC_17820 1.67e-127 367.0 COG1043@1|root,COG1043@2|Bacteria,1MUHQ@1224|Proteobacteria,1RPHB@1236|Gammaproteobacteria,1XSN6@135623|Vibrionales 135623|Vibrionales M Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxA GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0008654,GO:0008780,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.129 ko:K00677 ko00540,ko01100,ko01503,map00540,map01100,map01503 M00060 R04567 RC00039,RC00055 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Acetyltransf_11,Hexapep k141_37330_1 1042377.AFPJ01000016_gene113 1.76e-66 206.0 COG3122@1|root,COG3122@2|Bacteria,1N15V@1224|Proteobacteria,1S5V0@1236|Gammaproteobacteria,467D6@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria yaiL GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K09912 - - - - ko00000 - - iECW_1372.ECW_m0432,iWFL_1372.ECW_m0432 DUF2058 k141_37330_2 1042377.AFPJ01000016_gene112 1.66e-36 127.0 COG3310@1|root,COG3310@2|Bacteria,1RDE0@1224|Proteobacteria,1S3X6@1236|Gammaproteobacteria,467Z8@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria - - - ko:K09941 - - - - ko00000 - - - DUF1415 k141_29041_1 251229.Chro_3610 1.8e-88 285.0 COG1452@1|root,COG1452@2|Bacteria,1G0TW@1117|Cyanobacteria,3VHNX@52604|Pleurocapsales 1117|Cyanobacteria M PFAM Mannosyl oligosaccharide glucosidase - - - - - - - - - - - - Glyco_hydro_63 k141_31371_2 441769.ABFU01000029_gene1079 1.78e-06 49.3 COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,4HA8S@91061|Bacilli,1ZMFN@1386|Bacillus 91061|Bacilli J Translation initiation factor IF-2, N-terminal region infB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,IF-2,IF2_N k141_11350_1 234267.Acid_1254 3.22e-48 165.0 COG1260@1|root,COG1260@2|Bacteria,3Y325@57723|Acidobacteria 57723|Acidobacteria I Myo-inositol-1-phosphate synthase, GAPDH domain protein - - 5.5.1.4 ko:K01858 ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130 - R07324 RC01804 ko00000,ko00001,ko01000 - - - Inos-1-P_synth,NAD_binding_5 k141_17156_1 1042377.AFPJ01000005_gene2464 1.43e-05 46.6 COG0226@1|root,COG0226@2|Bacteria,1MUH9@1224|Proteobacteria,1RN9U@1236|Gammaproteobacteria,464BK@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0226 ABC-type phosphate transport system, periplasmic component pstS - - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - PBP_like_2 k141_37331_1 501479.ACNW01000065_gene3280 3.59e-23 91.7 COG5319@1|root,COG5319@2|Bacteria,1MZN2@1224|Proteobacteria,2UBTA@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein conserved in bacteria MA20_39715 - - - - - - - - - - - DUF1178 k141_37331_2 1294273.roselon_00104 9.66e-53 172.0 COG1028@1|root,COG1028@2|Bacteria,1RHYX@1224|Proteobacteria,2TUR9@28211|Alphaproteobacteria 28211|Alphaproteobacteria IQ Belongs to the short-chain dehydrogenases reductases (SDR) family csgA - - - - - - - - - - - adh_short k141_13804_1 1279017.AQYJ01000018_gene827 3.68e-146 457.0 COG0770@1|root,COG2843@1|root,COG0770@2|Bacteria,COG2843@2|Bacteria,1QTSF@1224|Proteobacteria,1RMGD@1236|Gammaproteobacteria,464UU@72275|Alteromonadaceae 1236|Gammaproteobacteria M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein - - - - - - - - - - - - Mur_ligase_C,Mur_ligase_M,PGA_cap k141_2875_1 1279017.AQYJ01000028_gene2274 8.58e-78 249.0 COG0366@1|root,COG0366@2|Bacteria,1MU90@1224|Proteobacteria,1RQ1S@1236|Gammaproteobacteria,465MB@72275|Alteromonadaceae 1236|Gammaproteobacteria G Alpha-amylase domain malS GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0004556,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009311,GO:0009313,GO:0009987,GO:0016052,GO:0016160,GO:0016787,GO:0016798,GO:0030288,GO:0030313,GO:0030978,GO:0030980,GO:0031975,GO:0042597,GO:0043167,GO:0043169,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044464,GO:0046872,GO:0051691,GO:0051692,GO:0071704,GO:1901575 3.2.1.1 ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 - R02108,R02112,R11262 - ko00000,ko00001,ko01000 - GH13 iECABU_c1320.ECABU_c40140,iECP_1309.ECP_3675,iECSE_1348.ECSE_3847,iPC815.YPO4080,ic_1306.c4392 Alpha-amylase k141_13827_3 1280001.BAOA01000077_gene3084 1.22e-100 293.0 COG1666@1|root,COG1666@2|Bacteria,1RDTF@1224|Proteobacteria,1S3RU@1236|Gammaproteobacteria,1XX34@135623|Vibrionales 135623|Vibrionales S Belongs to the UPF0234 family yajQ - - ko:K09767 - - - - ko00000 - - - DUF520 k141_13827_4 1116375.VEJY3_07670 9.23e-245 673.0 COG0722@1|root,COG0722@2|Bacteria,1MU5Q@1224|Proteobacteria,1RMAA@1236|Gammaproteobacteria,1XUX8@135623|Vibrionales 135623|Vibrionales E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) aroH - 2.5.1.54 ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 - - - DAHP_synth_1 k141_24310_1 1340434.AXVA01000004_gene2586 8.41e-76 228.0 COG0645@1|root,COG0645@2|Bacteria,1UCU3@1239|Firmicutes,4HE7Y@91061|Bacilli,1ZEC4@1386|Bacillus 91061|Bacilli S AAA domain - - - - - - - - - - - - AAA_33 k141_24310_2 218284.CCDN010000001_gene1422 7.36e-27 101.0 COG4768@1|root,COG4768@2|Bacteria,1UBBB@1239|Firmicutes,4IMQ8@91061|Bacilli,1ZKKT@1386|Bacillus 91061|Bacilli S protein containing a divergent version of the methyl-accepting chemotaxis-like domain - - - - - - - - - - - - DUF948 k141_10215_2 441769.ABFU01000065_gene1864 2.37e-111 328.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HAKV@91061|Bacilli,1ZPZN@1386|Bacillus 91061|Bacilli I acyl-CoA dehydrogenase acdA - 1.3.8.1,1.3.8.7 ko:K00248,ko:K00249 ko00071,ko00280,ko00410,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map00650,map01100,map01110,map01120,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01178,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00120,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_12640_1 999141.GME_07909 1.96e-29 112.0 COG0010@1|root,COG0010@2|Bacteria,1MVFH@1224|Proteobacteria,1RMH5@1236|Gammaproteobacteria,1XHZF@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the arginase family - - 3.5.3.11,3.5.3.7 ko:K01480,ko:K12255 ko00330,ko01100,map00330,map01100 M00133 R01157,R01990 RC00024,RC00329 ko00000,ko00001,ko00002,ko01000 - - - Arginase k141_12640_2 42565.FP66_10130 2.23e-77 243.0 COG3314@1|root,COG3314@2|Bacteria,1NEAN@1224|Proteobacteria,1RPX6@1236|Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - Gate k141_1677_1 796606.BMMGA3_11785 6.51e-83 248.0 COG0605@1|root,COG0605@2|Bacteria,1TPXT@1239|Firmicutes,4HA6U@91061|Bacilli,1ZBWK@1386|Bacillus 91061|Bacilli P radicals which are normally produced within the cells and which are toxic to biological systems sodA GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1 ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 - - - ko00000,ko00001,ko01000 - - - Sod_Fe_C,Sod_Fe_N k141_37351_1 42565.FP66_02600 2.76e-66 209.0 COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,1RNMX@1236|Gammaproteobacteria,1XHRU@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde argC - 1.2.1.38 ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R03443 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC k141_37351_2 42565.FP66_02595 0.000349 40.8 COG0316@1|root,COG0316@2|Bacteria,1RHCW@1224|Proteobacteria,1S675@1236|Gammaproteobacteria,1XKGW@135619|Oceanospirillales 135619|Oceanospirillales C iron-sulfur cluster insertion protein erpA erpA - - ko:K15724 - - - - ko00000 - - - Fe-S_biosyn k141_29059_1 42565.FP66_05805 4.91e-106 330.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XJ1B@135619|Oceanospirillales 135619|Oceanospirillales T Diguanylate cyclase - - - - - - - - - - - - EAL,GAF_2,GGDEF,PAS,PAS_9 k141_712_1 1453501.JELR01000001_gene2912 4.58e-53 173.0 COG0476@1|root,COG0476@2|Bacteria,1MW7H@1224|Proteobacteria,1RPJ3@1236|Gammaproteobacteria,466BQ@72275|Alteromonadaceae 1236|Gammaproteobacteria H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 moeB - 2.7.7.73,2.7.7.80 ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07459 RC00043 ko00000,ko00001,ko01000 - - - ThiF k141_712_2 1453501.JELR01000001_gene2913 4.41e-161 467.0 COG0351@1|root,COG0352@1|root,COG0351@2|Bacteria,COG0352@2|Bacteria,1MU9J@1224|Proteobacteria,1RNFP@1236|Gammaproteobacteria,4646B@72275|Alteromonadaceae 1236|Gammaproteobacteria H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) thiE - 2.5.1.3,2.7.1.49,2.7.4.7 ko:K14153 ko00730,ko01100,map00730,map01100 M00127 R03223,R03471,R04509,R10712 RC00002,RC00017,RC00224,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 - - - Phos_pyr_kin,TMP-TENI k141_25648_4 1279017.AQYJ01000022_gene2606 3.57e-132 377.0 29B18@1|root,2ZY02@2|Bacteria,1REMG@1224|Proteobacteria,1S4B1@1236|Gammaproteobacteria,46AUF@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_25648_5 1042377.AFPJ01000035_gene2637 2.52e-108 317.0 2C5F4@1|root,31I7F@2|Bacteria,1RHUH@1224|Proteobacteria,1S7M2@1236|Gammaproteobacteria,46BAF@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_25648_7 1453501.JELR01000001_gene3246 1.65e-176 501.0 COG1196@1|root,COG1196@2|Bacteria,1R4BS@1224|Proteobacteria,1S13B@1236|Gammaproteobacteria,466JA@72275|Alteromonadaceae 1236|Gammaproteobacteria D von Willebrand factor (vWF) type A domain - - - - - - - - - - - - VWA_2 k141_25648_9 1279017.AQYJ01000022_gene2611 3.56e-167 469.0 COG0811@1|root,COG0811@2|Bacteria,1NXZ9@1224|Proteobacteria,1S154@1236|Gammaproteobacteria,465XD@72275|Alteromonadaceae 1236|Gammaproteobacteria U MotA/TolQ/ExbB proton channel family - - - - - - - - - - - - MotA_ExbB k141_25648_11 1453501.JELR01000001_gene3242 0.0 1100.0 COG1262@1|root,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,1RQVS@1236|Gammaproteobacteria,46674@72275|Alteromonadaceae 1236|Gammaproteobacteria S PEGA domain - - - - - - - - - - - - FGE-sulfatase,PEGA k141_25648_12 1042377.AFPJ01000035_gene2630 5.51e-207 592.0 COG0457@1|root,COG0457@2|Bacteria,1RC07@1224|Proteobacteria,1S36N@1236|Gammaproteobacteria,46864@72275|Alteromonadaceae 1236|Gammaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_8 k141_25648_13 1042377.AFPJ01000035_gene2629 3.91e-208 585.0 28MBM@1|root,2ZAQ2@2|Bacteria,1R5V6@1224|Proteobacteria,1S0K0@1236|Gammaproteobacteria,4662R@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_17188_1 1996.JOFO01000003_gene6269 3.48e-23 100.0 COG0524@1|root,COG0524@2|Bacteria,2I04R@201174|Actinobacteria,4EHGW@85012|Streptosporangiales 201174|Actinobacteria G Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway rbsK - 2.7.1.15 ko:K00852 ko00030,map00030 - R01051,R02750 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB k141_17188_2 1128421.JAGA01000001_gene2143 2.65e-13 69.7 COG1957@1|root,COG1957@2|Bacteria,2NPG1@2323|unclassified Bacteria 2|Bacteria F Inosine-uridine preferring nucleoside hydrolase - - 3.2.2.1 ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 - R01245,R01273,R01677,R01770,R02143 RC00033,RC00063,RC00122,RC00318,RC00485 ko00000,ko00001,ko01000 - - - IU_nuc_hydro k141_33884_1 1279017.AQYJ01000024_gene935 4.22e-281 792.0 COG1629@1|root,COG4771@2|Bacteria,1MUNK@1224|Proteobacteria,1RN9S@1236|Gammaproteobacteria,464ZY@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_37352_1 218284.CCDN010000006_gene3522 1.47e-44 145.0 2DPT3@1|root,3339Q@2|Bacteria,1VJ5A@1239|Firmicutes,4HP0F@91061|Bacilli,1ZIZE@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2573) yusU - - - - - - - - - - - DUF2573 k141_37352_2 218284.CCDN010000006_gene3523 1.71e-28 109.0 COG4114@1|root,COG4114@2|Bacteria,1V28K@1239|Firmicutes,4HGQ8@91061|Bacilli,1ZB7Y@1386|Bacillus 91061|Bacilli S FhuF 2Fe-2S C-terminal domain - - - - - - - - - - - - FhuF,FhuF_C k141_24312_1 1279017.AQYJ01000026_gene337 2.65e-108 325.0 COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,1RMIX@1236|Gammaproteobacteria,46453@72275|Alteromonadaceae 1236|Gammaproteobacteria M zinc metalloprotease rseP GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016021,GO:0016787,GO:0019219,GO:0019222,GO:0019538,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0043170,GO:0043856,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0045152,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:0140110,GO:1901564,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - ko:K11749 ko02024,ko04112,map02024,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - PDZ,PDZ_2,Peptidase_M50 k141_11383_1 983545.Glaag_2040 2.58e-09 59.3 COG1816@1|root,COG1816@2|Bacteria,1R6Q8@1224|Proteobacteria,1S01A@1236|Gammaproteobacteria,465U7@72275|Alteromonadaceae 1236|Gammaproteobacteria F Adenosine/AMP deaminase - - 3.5.4.4 ko:K19572 ko00230,ko01100,map00230,map01100 - R01560 RC00477 ko00000,ko00001,ko01000 - - - A_deaminase k141_11383_2 1123257.AUFV01000007_gene323 2.01e-156 452.0 COG5042@1|root,COG5042@2|Bacteria,1NAN9@1224|Proteobacteria,1RZIP@1236|Gammaproteobacteria,1X4KA@135614|Xanthomonadales 135614|Xanthomonadales F Purine nucleoside permease (NUP) - - - - - - - - - - - - NUP k141_8971_1 377629.TERTU_2605 4.01e-93 285.0 COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,1RNPY@1236|Gammaproteobacteria,2PPQ1@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria O Peptidase family U32 C-terminal domain yegQ GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K08303 ko05120,map05120 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_U32,Peptidase_U32_C k141_12642_1 983545.Glaag_0671 2.56e-79 264.0 COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,1RPYH@1236|Gammaproteobacteria,46403@72275|Alteromonadaceae 1236|Gammaproteobacteria K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoC GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 k141_29060_1 1144305.PMI02_01324 4.09e-39 146.0 COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,2TSGE@28211|Alphaproteobacteria,2K04M@204457|Sphingomonadales 204457|Sphingomonadales S Sulfotransferase family - - - - - - - - - - - - Sulfotransfer_3 k141_25649_1 1294265.JCM21738_2988 1.01e-82 256.0 COG1169@1|root,COG1169@2|Bacteria,1TSRT@1239|Firmicutes,4H9K8@91061|Bacilli,1ZB3V@1386|Bacillus 91061|Bacilli HQ Isochorismate synthase menF - 5.4.4.2 ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 M00116 R01717 RC00588 ko00000,ko00001,ko00002,ko01000 - - - Chorismate_bind k141_25649_2 1294265.JCM21738_2989 3.86e-35 127.0 COG1575@1|root,COG1575@2|Bacteria,1TSZV@1239|Firmicutes,4HA68@91061|Bacilli,1ZB6F@1386|Bacillus 91061|Bacilli H Belongs to the MenA family. Type 1 subfamily menA GO:0003674,GO:0003824,GO:0004659,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006775,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016765,GO:0032194,GO:0042180,GO:0042181,GO:0042362,GO:0042371,GO:0042373,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.74 ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R05617,R06858,R10757 RC02935,RC02936,RC03264 ko00000,ko00001,ko00002,ko01000,ko01006 - - - UbiA k141_16009_2 218284.CCDN010000007_gene3814 2.8e-104 319.0 COG3887@1|root,COG3887@2|Bacteria,1TPGP@1239|Firmicutes,4HBVH@91061|Bacilli,1ZCB0@1386|Bacillus 91061|Bacilli T signaling protein consisting of a modified GGDEF domain and a DHH domain yybT - - - - - - - - - - - DHH,DHHA1 k141_2889_1 568703.LGG_01887 5.73e-53 169.0 2B9ZZ@1|root,323DM@2|Bacteria,1V6N4@1239|Firmicutes,4HXZB@91061|Bacilli,3FB39@33958|Lactobacillaceae 1239|Firmicutes S COG NOG15344 non supervised orthologous group - - - - - - - - - - - - - k141_2889_2 946235.CAER01000078_gene527 3.38e-12 60.5 2EQ31@1|root,33HPE@2|Bacteria,1VKKU@1239|Firmicutes,4HSHY@91061|Bacilli,23MC6@182709|Oceanobacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_10218_1 218284.CCDN010000001_gene1141 1.79e-104 328.0 COG0847@1|root,COG1199@1|root,COG0847@2|Bacteria,COG1199@2|Bacteria,1TQHQ@1239|Firmicutes,4HB2Y@91061|Bacilli,1ZAWI@1386|Bacillus 91061|Bacilli L helicase involved in DNA repair and perhaps also replication dinG - 3.6.4.12 ko:K03722 - - - - ko00000,ko01000,ko03400 - - - DEAD,Helicase_C_2,RNase_T,ResIII k141_11384_1 218284.CCDN010000001_gene1609 5.44e-95 277.0 COG1051@1|root,COG1051@2|Bacteria,1V9D6@1239|Firmicutes,4HICH@91061|Bacilli,1ZHU8@1386|Bacillus 91061|Bacilli F NUDIX hydrolase - - - - - - - - - - - - NUDIX k141_5431_1 1246484.D479_16144 1.8e-69 218.0 COG1464@1|root,COG1464@2|Bacteria,1TQAS@1239|Firmicutes,4HCTA@91061|Bacilli,3NECB@45667|Halobacillus 91061|Bacilli M NLPA lipoprotein metQ_3 - - ko:K02073 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - Lipoprotein_9 k141_26971_1 1279017.AQYJ01000029_gene3683 6.74e-87 277.0 COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,1RM95@1236|Gammaproteobacteria,465BW@72275|Alteromonadaceae 1236|Gammaproteobacteria I Acetyl propionyl-CoA carboxylase, alpha subunit mccA - 6.4.1.4,6.4.1.5 ko:K01968,ko:K13777 ko00280,ko00281,ko01100,map00280,map00281,map01100 M00036 R03494,R04138 RC00367,RC00942 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2 k141_20728_1 1231057.AMGD01000028_gene1965 6.67e-76 229.0 COG1670@1|root,COG1670@2|Bacteria,1V485@1239|Firmicutes,4HHFN@91061|Bacilli 91061|Bacilli J Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1 k141_33885_1 1535422.ND16A_3547 7.78e-29 109.0 COG5588@1|root,COG5588@2|Bacteria,1RGIE@1224|Proteobacteria,1S992@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF1326) - - - - - - - - - - - - DUF1326 k141_33885_2 1380390.JIAT01000010_gene3620 8.63e-54 172.0 COG0789@1|root,COG0789@2|Bacteria,2GKTU@201174|Actinobacteria,4CQ1W@84995|Rubrobacteria 84995|Rubrobacteria K MerR, DNA binding - - - ko:K13639 - - - - ko00000,ko03000 - - - MerR,MerR-DNA-bind k141_4179_1 1042377.AFPJ01000024_gene743 3.21e-100 309.0 COG2199@1|root,COG3706@2|Bacteria,1MWHH@1224|Proteobacteria,1RRU7@1236|Gammaproteobacteria,465TD@72275|Alteromonadaceae 1236|Gammaproteobacteria T 7TMR-DISM extracellular 2 - - - - - - - - - - - - 7TMR-DISMED2,7TMR-DISM_7TM,GGDEF k141_14767_1 218284.CCDN010000003_gene3009 2.65e-103 313.0 COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,4HB31@91061|Bacilli,1ZARE@1386|Bacillus 91061|Bacilli EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia pabB GO:0000162,GO:0000287,GO:0003674,GO:0003824,GO:0004049,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006575,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009108,GO:0009308,GO:0009309,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042398,GO:0042401,GO:0042430,GO:0042435,GO:0042558,GO:0042559,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 2.6.1.85 ko:K01665 ko00790,map00790 - R01716 RC00010,RC01418 ko00000,ko00001,ko01000 - - - Anth_synt_I_N,Chorismate_bind k141_5433_1 1499685.CCFJ01000046_gene3356 3.56e-34 117.0 2E4YS@1|root,32ZSJ@2|Bacteria,1VEX3@1239|Firmicutes,4HNZ8@91061|Bacilli,1ZIT3@1386|Bacillus 91061|Bacilli - - yrzR - - - - - - - - - - - - k141_26972_1 530564.Psta_4424 7.53e-22 102.0 COG0457@1|root,COG2956@1|root,COG0457@2|Bacteria,COG2956@2|Bacteria,2IXCM@203682|Planctomycetes 203682|Planctomycetes G Tetratricopeptide repeat - - - - - - - - - - - - TPR_16,TPR_8 k141_10219_1 1042377.AFPJ01000037_gene2946 3.78e-131 396.0 COG1629@1|root,COG4771@2|Bacteria,1QYDM@1224|Proteobacteria,1RYCH@1236|Gammaproteobacteria,469WZ@72275|Alteromonadaceae 1236|Gammaproteobacteria P TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_33886_1 218284.CCDN010000006_gene3662 6.82e-60 196.0 COG0168@1|root,COG0168@2|Bacteria,1TQ4S@1239|Firmicutes,4H9ME@91061|Bacilli,1ZBJ9@1386|Bacillus 91061|Bacilli P Potassium ktrB_3 - - ko:K03498 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkH k141_33886_2 218284.CCDN010000006_gene3663 1.73e-44 149.0 COG0569@1|root,COG0569@2|Bacteria,1TQ9H@1239|Firmicutes,4HBPH@91061|Bacilli,1ZQ63@1386|Bacillus 91061|Bacilli P TrkA-N domain ktrA GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K03499 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkA_C,TrkA_N k141_13831_2 1042377.AFPJ01000043_gene883 1.13e-138 410.0 COG0477@1|root,COG2814@2|Bacteria,1QKNX@1224|Proteobacteria,1RXRI@1236|Gammaproteobacteria,46723@72275|Alteromonadaceae 1236|Gammaproteobacteria EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 k141_20729_1 1202768.JROF01000001_gene1580 1.65e-20 93.6 COG0277@1|root,arCOG00337@2157|Archaea,2XT8F@28890|Euryarchaeota,23SGR@183963|Halobacteria 183963|Halobacteria C COG0277 FAD FMN-containing dehydrogenases - - - - - - - - - - - - BBE,FAD_binding_4 k141_17190_1 1294265.JCM21738_3236 1.84e-175 494.0 COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,4H9SQ@91061|Bacilli,1ZBUI@1386|Bacillus 91061|Bacilli J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner ychF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - ko:K06942 - - - - ko00000,ko03009 - - - MMR_HSR1,YchF-GTPase_C k141_37354_1 745411.B3C1_01370 3.85e-62 212.0 COG2366@1|root,COG2366@2|Bacteria,1MVMH@1224|Proteobacteria,1RMPX@1236|Gammaproteobacteria,1J8DH@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S related to penicillin acylase - - 3.5.1.97 ko:K07116 - - - - ko00000,ko01000 - - - Penicil_amidase k141_37354_2 1348635.BBJY01000001_gene2415 9.34e-158 453.0 COG0534@1|root,COG0534@2|Bacteria,1MVRV@1224|Proteobacteria,1RRDQ@1236|Gammaproteobacteria,1XYN5@135623|Vibrionales 135623|Vibrionales V MatE - - - - - - - - - - - - MatE k141_35086_1 218284.CCDN010000001_gene777 1.7e-97 285.0 COG5663@1|root,COG5663@2|Bacteria,1V2IT@1239|Firmicutes,4HG86@91061|Bacilli,1ZDPA@1386|Bacillus 91061|Bacilli S Belongs to the 5'(3')-deoxyribonucleotidase family yqfW - - ko:K05967 - - - - ko00000 - - - NT5C k141_25652_1 218284.CCDN010000001_gene67 1.81e-52 182.0 COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,4HAWB@91061|Bacilli,1ZAQK@1386|Bacillus 91061|Bacilli J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS - 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1,zf-FPG_IleRS k141_717_1 1082933.MEA186_29287 7.51e-22 96.7 COG1175@1|root,COG1175@2|Bacteria,1MWB7@1224|Proteobacteria,2TQZY@28211|Alphaproteobacteria,43KJ7@69277|Phyllobacteriaceae 28211|Alphaproteobacteria G COG1175 ABC-type sugar transport systems permease components - - - ko:K02025 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - BPD_transp_1 k141_5434_2 1453501.JELR01000002_gene356 2.79e-11 63.9 COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,1RR68@1236|Gammaproteobacteria,464NZ@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate moaA GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016829,GO:0016830,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0061798,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.22 ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09394 RC03420 ko00000,ko00001,ko01000 - - iSbBS512_1146.SbBS512_E2571,ic_1306.c0862 Fer4_12,Mob_synth_C,Radical_SAM k141_10246_1 218284.CCDN010000008_gene4196 1.74e-88 263.0 COG1514@1|root,COG1514@2|Bacteria,1VCBK@1239|Firmicutes,4HM3V@91061|Bacilli,1ZHT8@1386|Bacillus 91061|Bacilli J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester ytlP GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 ko:K01975 - - - - ko00000,ko01000,ko03016 - - - LigT_PEase k141_13857_1 218284.CCDN010000005_gene3228 1.85e-103 328.0 COG3857@1|root,COG3857@2|Bacteria,1TQJW@1239|Firmicutes,4HAY6@91061|Bacilli,1ZC70@1386|Bacillus 91061|Bacilli L ATP-dependent helicase deoxyribonuclease subunit B rexB GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0004527,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.6.4.12 ko:K16899 - - - - ko00000,ko01000,ko03400 - - - Exonuc_V_gamma,PDDEXK_1,UvrD_C k141_5451_1 1042377.AFPJ01000036_gene1190 1.88e-41 147.0 COG4446@1|root,COG4446@2|Bacteria,1N31A@1224|Proteobacteria,1RRKY@1236|Gammaproteobacteria,466QZ@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF1499) - - - - - - - - - - - - DUF1499 k141_1696_1 997296.PB1_16374 2.71e-22 94.7 COG1191@1|root,COG1191@2|Bacteria 2|Bacteria K sigma factor activity - - - ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 - - - ko00000,ko00001,ko02035,ko03021 - - - Sigma70_r2,Sigma70_r4 k141_1696_3 95619.PM1_0217555 9.92e-13 70.1 COG2197@1|root,COG2197@2|Bacteria,1NA3X@1224|Proteobacteria 1224|Proteobacteria KT HNH endonuclease - - - - - - - - - - - - HNH_3 k141_36134_1 218284.CCDN010000001_gene278 8.28e-13 67.0 COG4948@1|root,COG4948@2|Bacteria,1TQMS@1239|Firmicutes,4HCY5@91061|Bacilli,1ZC5Y@1386|Bacillus 91061|Bacilli M Belongs to the mandelate racemase muconate lactonizing enzyme family - - - - - - - - - - - - MR_MLE_C,MR_MLE_N k141_36134_2 218284.CCDN010000001_gene279 1.38e-88 265.0 COG1670@1|root,COG1670@2|Bacteria,1V3EY@1239|Firmicutes,4HGKG@91061|Bacilli,1ZG8B@1386|Bacillus 91061|Bacilli J Benzoate transporter - - - - - - - - - - - - Acetyltransf_1 k141_32541_1 498211.CJA_0913 1.31e-15 77.4 COG0810@1|root,COG0810@2|Bacteria,1PEER@1224|Proteobacteria,1RPPU@1236|Gammaproteobacteria,1FG7X@10|Cellvibrio 1236|Gammaproteobacteria M Chalcone isomerase-like - - - ko:K03832 - - - - ko00000,ko02000 2.C.1.1 - - Chalcone_3,TonB_2,TonB_C k141_32541_2 1042377.AFPJ01000035_gene2653 0.0 985.0 COG3590@1|root,COG3590@2|Bacteria,1MVNQ@1224|Proteobacteria,1RNNA@1236|Gammaproteobacteria,464DA@72275|Alteromonadaceae 1236|Gammaproteobacteria O Peptidase, M13 pepO - 3.4.24.71 ko:K01415,ko:K07386 - - - - ko00000,ko01000,ko01002,ko04147 - - - Peptidase_M13,Peptidase_M13_N k141_16031_1 1347086.CCBA010000027_gene3509 9.76e-123 357.0 COG1307@1|root,COG1307@2|Bacteria,1TQDI@1239|Firmicutes,4HAYQ@91061|Bacilli,1ZCK2@1386|Bacillus 91061|Bacilli S protein conserved in bacteria yitS - - - - - - - - - - - DegV k141_27756_2 218284.CCDN010000004_gene3152 3.67e-165 473.0 COG0189@1|root,COG0189@2|Bacteria,1U4ME@1239|Firmicutes,4HFD2@91061|Bacilli,1ZBNP@1386|Bacillus 91061|Bacilli HJ YheC/D like ATP-grasp yheC - - - - - - - - - - - ATPgrasp_YheCD k141_7815_3 1280001.BAOA01000007_gene3877 5.83e-52 177.0 COG4166@1|root,COG4166@2|Bacteria,1P91R@1224|Proteobacteria,1RN57@1236|Gammaproteobacteria,1XVN1@135623|Vibrionales 135623|Vibrionales E Bacterial extracellular solute-binding proteins, family 5 Middle - - - ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 k141_1832_1 926569.ANT_14740 4.51e-45 158.0 COG0482@1|root,COG0482@2|Bacteria,2G64I@200795|Chloroflexi 200795|Chloroflexi J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 mnmA - 2.8.1.13 ko:K00566 ko04122,map04122 - R08700 RC02313,RC02315 ko00000,ko00001,ko01000,ko03016 - - - tRNA_Me_trans k141_4294_1 1294265.JCM21738_1816 2.41e-41 144.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4H9SC@91061|Bacilli,1ZBEE@1386|Bacillus 91061|Bacilli V ABC transporter malQ - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran k141_4294_2 1294265.JCM21738_1815 6.25e-123 359.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,1ZBIW@1386|Bacillus 91061|Bacilli V COG1132 ABC-type multidrug transport system, ATPase and permease components yfiC3 - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran k141_25860_1 1536773.R70331_30555 8.77e-79 243.0 COG4589@1|root,COG4589@2|Bacteria,1V05D@1239|Firmicutes,4HDND@91061|Bacilli,26R8U@186822|Paenibacillaceae 91061|Bacilli S CDP-diglyceride synthetase cdsA3 - 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_1 k141_29238_1 203122.Sde_0789 2.68e-95 286.0 COG3507@1|root,COG3507@2|Bacteria,1QBSN@1224|Proteobacteria,1RNBA@1236|Gammaproteobacteria,464BQ@72275|Alteromonadaceae 1236|Gammaproteobacteria G Glycosyl hydrolases family 43 - - - - - - - - - - - - AbfB,Glyco_hydro_43 k141_9177_1 1279017.AQYJ01000027_gene1948 2.09e-197 553.0 COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,1RMBM@1236|Gammaproteobacteria,464U3@72275|Alteromonadaceae 1236|Gammaproteobacteria G Catalyzes the NAD-dependent conversion of D-erythrose 4- phosphate to 4-phosphoerythronate epd GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019318,GO:0019438,GO:0019637,GO:0034641,GO:0036094,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0043891,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0048001,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.2.1.12,1.2.1.72 ko:K00134,ko:K03472 ko00010,ko00710,ko00750,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map00750,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00124,M00165,M00166,M00308,M00552 R01061,R01825 RC00149,RC00242 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - iYL1228.KPN_03356 Gp_dh_C,Gp_dh_N k141_11591_2 218284.CCDN010000001_gene1192 4.07e-94 285.0 COG1413@1|root,COG1413@2|Bacteria,1TRJT@1239|Firmicutes,4HBFD@91061|Bacilli,1ZB7F@1386|Bacillus 91061|Bacilli C COG0694 Thioredoxin-like proteins and domains ypgR - - - - - - - - - - - HEAT_2,HEAT_PBS,Nfu_N,Virulence_fact k141_19798_1 1453501.JELR01000001_gene2863 1.15e-86 271.0 COG2072@1|root,COG2072@2|Bacteria,1MU71@1224|Proteobacteria,1RP8X@1236|Gammaproteobacteria,465CT@72275|Alteromonadaceae 1236|Gammaproteobacteria P flavoprotein involved in K transport ethA - - - - - - - - - - - FMO-like,NAD_binding_8,Pyr_redox_2,Pyr_redox_3 k141_12820_1 1268239.PALB_26310 3.52e-12 73.9 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MV8W@1224|Proteobacteria,1RMQA@1236|Gammaproteobacteria,2Q0DV@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_23478_1 278963.ATWD01000001_gene1745 1.29e-84 265.0 COG1032@1|root,COG1032@2|Bacteria,3Y2FN@57723|Acidobacteria,2JI6W@204432|Acidobacteriia 204432|Acidobacteriia C PFAM Radical SAM - - - - - - - - - - - - Radical_SAM k141_5646_1 218284.CCDN010000008_gene4162 8.5e-106 313.0 COG0715@1|root,COG0715@2|Bacteria,1TQN5@1239|Firmicutes,4HAB9@91061|Bacilli,1ZC0Z@1386|Bacillus 91061|Bacilli P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components ytlA GO:0003674,GO:0005215 - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1,NMT1_2 k141_5646_2 218284.CCDN010000008_gene4163 2.41e-91 273.0 COG1506@1|root,COG1506@2|Bacteria,1U5SB@1239|Firmicutes,4HB1A@91061|Bacilli,1ZC9W@1386|Bacillus 91061|Bacilli E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases ytmA - - - - - - - - - - - Peptidase_S9 k141_22141_2 42565.FP66_06580 1.61e-68 209.0 COG0098@1|root,COG0098@2|Bacteria,1MUS4@1224|Proteobacteria,1RNEV@1236|Gammaproteobacteria,1XHWV@135619|Oceanospirillales 135619|Oceanospirillales J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body rpsE - - ko:K02988 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S5,Ribosomal_S5_C k141_1833_1 218284.CCDN010000006_gene3685 8.01e-126 381.0 COG0653@1|root,COG0653@2|Bacteria,1TPEY@1239|Firmicutes,4HA22@91061|Bacilli,1ZAXF@1386|Bacillus 91061|Bacilli U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW k141_7816_1 345219.Bcoa_0374 6.78e-17 81.3 COG0179@1|root,COG0179@2|Bacteria,1TQDQ@1239|Firmicutes,4HCBR@91061|Bacilli,1ZCHF@1386|Bacillus 91061|Bacilli Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) yisK - 3.7.1.5 ko:K16164 ko00350,ko01100,ko01120,map00350,map01100,map01120 - R01085 RC00326,RC00446 ko00000,ko00001,ko01000 - - - FAA_hydrolase k141_24558_1 1294265.JCM21738_1714 2.18e-70 217.0 COG1284@1|root,COG1284@2|Bacteria,1TRBT@1239|Firmicutes,4HBPR@91061|Bacilli,1ZDFA@1386|Bacillus 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2179) yitT3 - - - - - - - - - - - DUF2179,YitT_membrane k141_24558_2 649639.Bcell_2379 1.43e-21 87.4 2C7Y4@1|root,34BFK@2|Bacteria,1W0Q4@1239|Firmicutes,4HYME@91061|Bacilli,1ZJ4X@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF1292) - - - - - - - - - - - - DUF1292 k141_17334_1 1042377.AFPJ01000020_gene2062 2.1e-170 490.0 COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,1RN2V@1236|Gammaproteobacteria 1236|Gammaproteobacteria P COG3119 Arylsulfatase A and related enzymes - - 3.1.6.1 ko:K01130 ko00140,ko00600,map00140,map00600 - R03980,R04856 RC00128,RC00231 ko00000,ko00001,ko01000 - - - Sulfatase,Sulfatase_C k141_14069_2 1116375.VEJY3_07415 1.36e-83 249.0 2DNV9@1|root,32ZB3@2|Bacteria,1MZGP@1224|Proteobacteria,1SE04@1236|Gammaproteobacteria,1XY7K@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_20864_1 1042377.AFPJ01000052_gene1568 5.21e-127 396.0 COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,1RMU1@1236|Gammaproteobacteria,464K7@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG1643 HrpA-like helicases hrpA GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0006139,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 3.6.4.13 ko:K03578 - - - - ko00000,ko01000 - - - DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind k141_35307_1 1453501.JELR01000001_gene3215 4.57e-130 382.0 COG3707@1|root,COG3707@2|Bacteria,1MXDV@1224|Proteobacteria,1RMQG@1236|Gammaproteobacteria,464HH@72275|Alteromonadaceae 1236|Gammaproteobacteria K Nitrate-and nitrite-responsive positive regulator nasR - - - - - - - - - - - ANTAR,NIT k141_19799_1 1453501.JELR01000002_gene152 3.68e-117 370.0 COG3164@1|root,COG3164@2|Bacteria,1MXWF@1224|Proteobacteria,1RNUK@1236|Gammaproteobacteria,464CY@72275|Alteromonadaceae 1236|Gammaproteobacteria S membrane yhdP GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0042597,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - - - - - - - - - - AsmA_2,DUF3971 k141_29239_2 68194.JNXR01000028_gene2147 4.37e-11 65.9 COG0711@1|root,COG0711@2|Bacteria,2GJS4@201174|Actinobacteria 201174|Actinobacteria C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) atpF - - ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_B k141_31433_1 1246484.D479_13572 1.41e-122 369.0 COG0550@1|root,COG0550@2|Bacteria,1TPUS@1239|Firmicutes,4HA6C@91061|Bacilli,3ND4T@45667|Halobacillus 91061|Bacilli L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topA - 5.99.1.2 ko:K03168 - - - - ko00000,ko01000,ko03032,ko03400 - - - Topoisom_bac,Toprim,zf-C4_Topoisom k141_22142_1 404589.Anae109_2042 5.67e-05 47.4 COG0494@1|root,COG0494@2|Bacteria,1RCZM@1224|Proteobacteria,42T10@68525|delta/epsilon subdivisions,2WPNN@28221|Deltaproteobacteria,2YVNK@29|Myxococcales 28221|Deltaproteobacteria L Nudix hydrolase - - 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - - NUDIX,NUDIX_4 k141_23479_2 218284.CCDN010000006_gene3503 1.33e-24 99.8 COG1135@1|root,COG1135@2|Bacteria,1TPPN@1239|Firmicutes,4H9VX@91061|Bacilli,1ZAZX@1386|Bacillus 91061|Bacilli P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system metN GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0008150,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085 - ko:K02071 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - iYO844.BSU32750 ABC_tran,NIL k141_11593_1 1279017.AQYJ01000024_gene1154 4.23e-74 231.0 COG0656@1|root,COG0656@2|Bacteria,1MWFS@1224|Proteobacteria,1RMX6@1236|Gammaproteobacteria,467B4@72275|Alteromonadaceae 1236|Gammaproteobacteria S Aldo/keto reductase family dkgA GO:0003674,GO:0003824,GO:0004033,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0008106,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0042180,GO:0042182,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0051596,GO:0055114,GO:0071704,GO:1901575 1.1.1.307,1.1.1.346 ko:K06221,ko:K17743 ko00040,ko01100,map00040,map01100 - R01431,R08878,R09477 RC00089,RC00133 ko00000,ko00001,ko01000 - - iECH74115_1262.ECH74115_4323,iECSP_1301.ECSP_3988 Aldo_ket_red k141_32732_1 1408312.JNJS01000006_gene875 9.44e-52 170.0 COG1838@1|root,COG1838@2|Bacteria,1V1CP@1239|Firmicutes,24FRK@186801|Clostridia,3NHNN@46205|Pseudobutyrivibrio 186801|Clostridia C Fumarase C-terminus fumB - 4.2.1.2 ko:K01678 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - - Fumerase_C k141_32732_2 1449126.JQKL01000008_gene277 3.55e-16 76.3 COG1951@1|root,COG1951@2|Bacteria,1TPXQ@1239|Firmicutes,248T7@186801|Clostridia,2685W@186813|unclassified Clostridiales 186801|Clostridia C Fumarate hydratase (Fumerase) - - 4.2.1.2 ko:K01677 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - - Fumerase k141_7817_1 218284.CCDN010000011_gene4403 9.39e-164 463.0 COG0533@1|root,COG0533@2|Bacteria,1TQDR@1239|Firmicutes,4HANB@91061|Bacilli,1ZBT3@1386|Bacillus 91061|Bacilli O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction tsaD GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 ko:K01409 - - R10648 RC00070,RC00416 ko00000,ko01000,ko03016 - - - Peptidase_M22 k141_3030_1 218284.CCDN010000005_gene3492 1.67e-273 760.0 COG1368@1|root,COG1368@2|Bacteria,1TRMA@1239|Firmicutes,4H9S0@91061|Bacilli,1ZBBV@1386|Bacillus 91061|Bacilli M Belongs to the LTA synthase family yfnI GO:0005575,GO:0005576 2.7.8.20 ko:K19005 ko00561,ko01100,map00561,map01100 - R05081,R10849 RC00017 ko00000,ko00001,ko01000 - - - Sulfatase k141_25861_3 218284.CCDN010000005_gene3312 2.82e-23 94.7 COG2323@1|root,COG2323@2|Bacteria,1TRWQ@1239|Firmicutes,4H9VA@91061|Bacilli,1ZCPH@1386|Bacillus 91061|Bacilli S membrane - - - - - - - - - - - - DUF1657,DUF421 k141_30287_1 1453501.JELR01000002_gene1360 7.89e-52 182.0 COG4206@1|root,COG4206@2|Bacteria,1MUZG@1224|Proteobacteria,1RP7I@1236|Gammaproteobacteria,463Z2@72275|Alteromonadaceae 1236|Gammaproteobacteria H COG1629 Outer membrane receptor proteins, mostly Fe transport - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - CarboxypepD_reg,Plug,TonB_dep_Rec k141_30287_3 1453501.JELR01000002_gene1362 7.3e-135 382.0 COG0131@1|root,COG0131@2|Bacteria,1MWBS@1224|Proteobacteria,1RPA9@1236|Gammaproteobacteria,4643N@72275|Alteromonadaceae 1236|Gammaproteobacteria E belongs to the histidinol- phosphatase family hisB GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0004424,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042578,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.15,4.2.1.19 ko:K01089,ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R03013,R03457 RC00017,RC00932 ko00000,ko00001,ko00002,ko01000 - - iECO111_1330.ECO111_2746,iECS88_1305.ECS88_2121,iJN746.PP_0289,iUMNK88_1353.UMNK88_2570 Hydrolase_like,IGPD,PNK3P k141_30287_4 1042377.AFPJ01000038_gene1118 5.66e-59 186.0 COG0118@1|root,COG0118@2|Bacteria,1MU4X@1224|Proteobacteria,1RRP3@1236|Gammaproteobacteria,465J2@72275|Alteromonadaceae 1236|Gammaproteobacteria E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR hisH GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - - GATase k141_29240_1 1123261.AXDW01000001_gene1112 3.31e-34 132.0 COG2885@1|root,COG2885@2|Bacteria,1RKGT@1224|Proteobacteria,1S6ZQ@1236|Gammaproteobacteria,1X563@135614|Xanthomonadales 1224|Proteobacteria M Belongs to the ompA family - - - - - - - - - - - - OmpA k141_17335_1 218284.CCDN010000002_gene2705 0.000287 40.8 2E6JV@1|root,334AK@2|Bacteria,1VIDD@1239|Firmicutes,4HQJG@91061|Bacilli 91061|Bacilli S Domain of unknown function (DUF3784) - - - - - - - - - - - - DUF3784 k141_30302_1 42565.FP66_01250 3.65e-08 53.5 COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,1RP4D@1236|Gammaproteobacteria,1XHIG@135619|Oceanospirillales 135619|Oceanospirillales E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine trpB - 4.2.1.20 ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - PALP k141_30302_2 42565.FP66_01245 3.48e-124 358.0 COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,1RMGN@1236|Gammaproteobacteria,1XHKU@135619|Oceanospirillales 135619|Oceanospirillales E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate trpA - 4.2.1.20 ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - Trp_syntA k141_14103_1 218284.CCDN010000009_gene4318 7.12e-95 283.0 COG1028@1|root,COG1028@2|Bacteria,1V1Z9@1239|Firmicutes,4HCPI@91061|Bacilli,1ZFQF@1386|Bacillus 91061|Bacilli IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) yueD - 1.1.1.320 ko:K16216 - - - - ko00000,ko01000 - - - adh_short k141_27189_1 1460640.JCM19046_941 4.99e-65 207.0 COG0189@1|root,COG0189@2|Bacteria,1TWCJ@1239|Firmicutes,4HCWW@91061|Bacilli,1ZDUV@1386|Bacillus 91061|Bacilli HJ Prokaryotic glutathione synthetase, ATP-grasp domain - - - ko:K05844 - - - - ko00000,ko01000,ko03009 - - - RimK k141_9203_1 925775.XVE_0484 2.22e-38 134.0 COG2151@1|root,COG2151@2|Bacteria,1MZ9Y@1224|Proteobacteria,1S36X@1236|Gammaproteobacteria,1X3XG@135614|Xanthomonadales 135614|Xanthomonadales S FeS assembly SUF system protein SufT - - - - - - - - - - - - FeS_assembly_P k141_19826_2 1408444.JHYC01000002_gene538 9.47e-08 56.2 COG1195@1|root,COG1195@2|Bacteria,1MX8N@1224|Proteobacteria,1RN5P@1236|Gammaproteobacteria,1JCMP@118969|Legionellales 118969|Legionellales L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP recF GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - ko:K03629 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - SMC_N k141_16194_1 1116375.VEJY3_15280 6.17e-45 152.0 COG0408@1|root,COG0408@2|Bacteria,1MWMF@1224|Proteobacteria,1RMM8@1236|Gammaproteobacteria,1XT68@135623|Vibrionales 135623|Vibrionales H Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX hemF GO:0003674,GO:0003824,GO:0004109,GO:0005488,GO:0005515,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0016634,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042802,GO:0042803,GO:0044237,GO:0044249,GO:0044271,GO:0046483,GO:0046983,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.3.3 ko:K00228 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03220 RC00884 ko00000,ko00001,ko00002,ko01000 - - - Coprogen_oxidas k141_16194_2 1219076.N646_2133 1.43e-127 363.0 COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,1S610@1236|Gammaproteobacteria,1XV14@135623|Vibrionales 135623|Vibrionales J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-) CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate tsaC GO:0000049,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 2.7.7.87 ko:K07566 - - R10463 RC00745 ko00000,ko01000,ko03009,ko03016 - - - Sua5_yciO_yrdC k141_16194_3 1280001.BAOA01000052_gene1652 3.36e-103 299.0 COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,1S3VN@1236|Gammaproteobacteria,1XUDA@135623|Vibrionales 135623|Vibrionales F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) purE GO:0003674,GO:0003824,GO:0004638,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 5.4.99.18 ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07405 RC01947 ko00000,ko00001,ko00002,ko01000 - - - AIRC k141_16194_4 223926.28808063 3.62e-45 155.0 COG0026@1|root,COG0026@2|Bacteria,1MU70@1224|Proteobacteria,1RQEI@1236|Gammaproteobacteria,1XU8Y@135623|Vibrionales 135623|Vibrionales F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) purK GO:0003674,GO:0003824,GO:0004638,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.18 ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07404 RC01927 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp k141_18780_2 218284.CCDN010000006_gene3652 2.38e-30 108.0 COG1983@1|root,COG1983@2|Bacteria,1VKBQ@1239|Firmicutes,4HRGW@91061|Bacilli,1ZJCV@1386|Bacillus 91061|Bacilli KT PspC domain yvlC - - ko:K03973 - - - - ko00000,ko02048,ko03000 - - - DUF4097,PspC k141_34067_1 1279017.AQYJ01000028_gene2300 7.63e-49 162.0 2E3UE@1|root,32YRS@2|Bacteria,1N75A@1224|Proteobacteria,1S9W5@1236|Gammaproteobacteria,468Q7@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF2799) - - - - - - - - - - - - DUF2799 k141_34067_3 1453501.JELR01000005_gene1641 6.87e-153 436.0 2B0GJ@1|root,31SU3@2|Bacteria,1RI4W@1224|Proteobacteria,1SA3Z@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_34067_4 1042377.AFPJ01000004_gene374 1.4e-52 184.0 COG2909@1|root,COG2909@2|Bacteria,1MVZZ@1224|Proteobacteria,1RN29@1236|Gammaproteobacteria,46AB4@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG2909 ATP-dependent transcriptional regulator malT GO:0003674,GO:0003700,GO:0005488,GO:0005515,GO:0005975,GO:0006355,GO:0008150,GO:0008152,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030246,GO:0031323,GO:0031326,GO:0042802,GO:0044238,GO:0048031,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070492,GO:0071704,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 - ko:K03556 - - - - ko00000,ko03000 - - - AAA_16,GerE k141_20880_1 1453501.JELR01000006_gene16 3.79e-46 160.0 COG1215@1|root,COG1215@2|Bacteria,1QTWU@1224|Proteobacteria,1T2FI@1236|Gammaproteobacteria,469X7@72275|Alteromonadaceae 1236|Gammaproteobacteria M Glycosyltransferase like family 2 gt2H - - - - - - - - - - - Glycos_transf_2 k141_20880_2 1042377.AFPJ01000045_gene2577 1.37e-09 57.8 COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,1RMBU@1236|Gammaproteobacteria,465GA@72275|Alteromonadaceae 1236|Gammaproteobacteria H Belongs to the NadC ModD family nadC GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034213,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605 2.4.2.19 ko:K00767 ko00760,ko01100,map00760,map01100 M00115 R03348 RC02877 ko00000,ko00001,ko00002,ko01000 - - iECP_1309.ECP_0109 QRPTase_C,QRPTase_N k141_31451_1 46429.BV95_03424 2.98e-248 701.0 COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,2TRSS@28211|Alphaproteobacteria,2K0VG@204457|Sphingomonadales 28211|Alphaproteobacteria C The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) - - 1.2.4.4 ko:K11381 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 M00036 R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00027,RC00627,RC02743,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh,Transket_pyr,Transketolase_C k141_14104_1 1348635.BBJY01000006_gene514 1.88e-81 250.0 COG0697@1|root,COG0697@2|Bacteria,1NDWV@1224|Proteobacteria,1SFS4@1236|Gammaproteobacteria,1XTF0@135623|Vibrionales 135623|Vibrionales EG of the drug metabolite transporter (DMT) superfamily VPA1529 - - - - - - - - - - - EamA k141_27190_1 574376.BAMA_13090 7.31e-31 124.0 COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4HBVV@91061|Bacilli,1ZB7Z@1386|Bacillus 91061|Bacilli S ABC transporter ydiF - - ko:K06158 - - - - ko00000,ko03012 - - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn k141_29268_1 1279017.AQYJ01000022_gene2686 6.86e-139 412.0 COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,1RNPT@1236|Gammaproteobacteria,464DV@72275|Alteromonadaceae 1236|Gammaproteobacteria C The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) aceF - 2.3.1.12 ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding k141_9204_1 1279017.AQYJ01000026_gene379 2.4e-46 169.0 COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,1RR0R@1236|Gammaproteobacteria,469YC@72275|Alteromonadaceae 1236|Gammaproteobacteria O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins - - - ko:K03798 - M00742 - - ko00000,ko00002,ko01000,ko01002,ko03110 - - - AAA,FtsH_ext,Peptidase_M41 k141_35312_1 1219076.N646_0334 1.32e-127 371.0 COG0027@1|root,COG0027@2|Bacteria,1N3KA@1224|Proteobacteria,1RNTW@1236|Gammaproteobacteria,1XUDQ@135623|Vibrionales 135623|Vibrionales F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate purT GO:0003674,GO:0003824,GO:0004644,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.2.2 ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04325,R04326 RC00026,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp,Epimerase k141_35312_2 1116375.VEJY3_06250 1.19e-150 424.0 COG0500@1|root,COG0500@2|Bacteria,1RAE4@1224|Proteobacteria,1S0RC@1236|Gammaproteobacteria,1XUYU@135623|Vibrionales 135623|Vibrionales H Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family tpm GO:0003674,GO:0003824,GO:0008119,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008757,GO:0010035,GO:0010038,GO:0016740,GO:0016741,GO:0032259,GO:0042221,GO:0050896 2.1.1.67 ko:K00569 ko00983,map00983 - R08236,R08239,R08246 RC00003,RC00980,RC02277 ko00000,ko00001,ko01000 - - - TPMT k141_35312_3 223926.28806283 4.8e-157 443.0 COG2357@1|root,COG2357@2|Bacteria,1MYTM@1224|Proteobacteria,1S795@1236|Gammaproteobacteria,1XVF3@135623|Vibrionales 135623|Vibrionales M protein conserved in bacteria - - - - - - - - - - - - RelA_SpoT k141_35312_5 1116375.VEJY3_06235 2.85e-187 523.0 COG0679@1|root,COG0679@2|Bacteria,1P2SH@1224|Proteobacteria,1S7N5@1236|Gammaproteobacteria,1XTMY@135623|Vibrionales 135623|Vibrionales S Membrane transport protein VV2066 - - ko:K07088 - - - - ko00000 - - - Mem_trans k141_35312_6 674977.VMC_18370 0.0 1499.0 COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1MWKS@1224|Proteobacteria,1RMIH@1236|Gammaproteobacteria,1XSJE@135623|Vibrionales 135623|Vibrionales J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily pheT GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - B3_4,B5,FDX-ACB,tRNA_bind k141_35312_7 1219076.N646_0328 2.15e-236 650.0 COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,1RN22@1236|Gammaproteobacteria,1XTCW@135623|Vibrionales 135623|Vibrionales J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily pheS GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 ko:K01889 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Phe_tRNA-synt_N,tRNA-synt_2d k141_35312_8 1116375.VEJY3_06200 2.27e-177 496.0 COG3655@1|root,COG3655@2|Bacteria,1NC3B@1224|Proteobacteria,1SDIR@1236|Gammaproteobacteria,1XSVT@135623|Vibrionales 135623|Vibrionales K Transcriptional regulator - - - - - - - - - - - - HTH_26 k141_35312_9 29495.EA26_15130 4.5e-71 214.0 COG0292@1|root,COG0292@2|Bacteria,1RGU2@1224|Proteobacteria,1S3P3@1236|Gammaproteobacteria,1XX9W@135623|Vibrionales 135623|Vibrionales J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit rplT GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02887 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L20 k141_35312_10 1280001.BAOA01000019_gene462 3.57e-37 125.0 COG0291@1|root,COG0291@2|Bacteria,1N6V4@1224|Proteobacteria,1SCHI@1236|Gammaproteobacteria,1XYEU@135623|Vibrionales 135623|Vibrionales J Belongs to the bacterial ribosomal protein bL35 family rpmI GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02916 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L35p k141_35312_11 1348635.BBJY01000010_gene1343 3.28e-84 249.0 COG0290@1|root,COG0290@2|Bacteria,1RDD2@1224|Proteobacteria,1S4E6@1236|Gammaproteobacteria,1XWWZ@135623|Vibrionales 135623|Vibrionales J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins infC - - ko:K02520 - - - - ko00000,ko03012,ko03029 - - - IF3_C,IF3_N k141_35312_12 223926.28806268 0.0 1288.0 COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,1RMYE@1236|Gammaproteobacteria,1XVD6@135623|Vibrionales 135623|Vibrionales J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) thrS GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD k141_35312_13 223926.28806267 1.93e-129 376.0 28RRT@1|root,2ZE4B@2|Bacteria,1RCHD@1224|Proteobacteria,1S345@1236|Gammaproteobacteria,1XTM3@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF3187) - - - - - - - - - - - - DUF3187 k141_1845_2 42565.FP66_11040 4.78e-113 337.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria C belongs to the aldehyde dehydrogenase family - - 1.2.1.3,1.2.1.8 ko:K00128,ko:K00130 ko00010,ko00053,ko00071,ko00260,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00260,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135,M00555 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02565,R02566,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_27191_2 1294265.JCM21738_1908 3.52e-99 292.0 COG0623@1|root,COG0623@2|Bacteria,1TPVD@1239|Firmicutes,4H9YN@91061|Bacilli,1ZAP0@1386|Bacillus 91061|Bacilli I Enoyl- acyl-carrier-protein reductase NADH fabI GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006950,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0033554,GO:0036094,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051716,GO:0055114,GO:0065003,GO:0070417,GO:0071704,GO:0071840,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.3.1.10,1.3.1.9 ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 M00083,M00572 R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671 RC00052,RC00076,RC00120 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 k141_18781_1 218284.CCDN010000001_gene588 1.02e-101 296.0 COG0622@1|root,COG0622@2|Bacteria,1VA0U@1239|Firmicutes,4HM24@91061|Bacilli,1ZH0K@1386|Bacillus 91061|Bacilli S Phosphoesterase ysnB GO:0003674,GO:0005488,GO:0008270,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - ko:K07095 - - - - ko00000 - - - Metallophos_2 k141_18781_2 218284.CCDN010000001_gene587 2.78e-76 231.0 COG0127@1|root,COG0127@2|Bacteria,1V6RN@1239|Firmicutes,4HCP6@91061|Bacilli,1ZFJM@1386|Bacillus 91061|Bacilli F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions rdgB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 ko:K02428 ko00230,map00230 - R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000 - - - Ham1p_like k141_24586_1 1453501.JELR01000002_gene877 2.06e-60 189.0 COG2947@1|root,COG2947@2|Bacteria,1RHRU@1224|Proteobacteria,1S68X@1236|Gammaproteobacteria,467AM@72275|Alteromonadaceae 1236|Gammaproteobacteria S EVE domain - - - - - - - - - - - - EVE k141_24586_3 1279017.AQYJ01000020_gene1292 2.26e-121 350.0 COG0778@1|root,COG0778@2|Bacteria,1MY39@1224|Proteobacteria,1RS8B@1236|Gammaproteobacteria,46DGX@72275|Alteromonadaceae 1236|Gammaproteobacteria C Nitroreductase family - - - - - - - - - - - - Nitroreductase k141_24586_4 1279017.AQYJ01000020_gene1293 1.95e-13 65.1 2EN5A@1|root,33FT9@2|Bacteria,1NH74@1224|Proteobacteria,1SHI0@1236|Gammaproteobacteria,46960@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF3094) - - - - - - - - - - - - DUF3094 k141_22181_2 1042377.AFPJ01000052_gene1523 1.59e-150 437.0 COG2925@1|root,COG2925@2|Bacteria,1MV0U@1224|Proteobacteria,1RM85@1236|Gammaproteobacteria,464RJ@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG2925 Exonuclease I sbcB GO:0000175,GO:0000287,GO:0000738,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004532,GO:0004536,GO:0004540,GO:0005488,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0008852,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016829,GO:0016835,GO:0016895,GO:0016896,GO:0019439,GO:0034641,GO:0034655,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0046872,GO:0051575,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0140097,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575 3.1.11.1 ko:K01141 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_X-T_C,RNase_T k141_12834_2 1279017.AQYJ01000028_gene2496 5.31e-78 235.0 COG2867@1|root,COG2867@2|Bacteria,1RGUH@1224|Proteobacteria,1S61C@1236|Gammaproteobacteria,4675X@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG2867 Oligoketide cyclase lipid transport protein ratA GO:0003674,GO:0005488,GO:0006417,GO:0006446,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044877,GO:0045947,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:2000112,GO:2000113 - - - - - - - - - - Polyketide_cyc k141_12834_3 1042377.AFPJ01000051_gene61 5.02e-52 166.0 COG2914@1|root,COG2914@2|Bacteria,1MZCH@1224|Proteobacteria,1SCHG@1236|Gammaproteobacteria,467WA@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the UPF0125 (RnfH) family rnfH - - ko:K09801 - - - - ko00000 - - - Ub-RnfH k141_14105_1 1347086.CCBA010000012_gene1997 7.55e-91 275.0 COG0674@1|root,COG0674@2|Bacteria,1TSSC@1239|Firmicutes,4HA8C@91061|Bacilli,1ZF89@1386|Bacillus 91061|Bacilli C Pyruvate:ferredoxin oxidoreductase core domain II - - 1.2.7.11,1.2.7.3 ko:K00174 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - PFOR_II,POR_N k141_30304_1 218284.CCDN010000005_gene3322 1.15e-66 211.0 COG2358@1|root,COG2358@2|Bacteria,1TPXW@1239|Firmicutes,4HB7U@91061|Bacilli,1ZEBW@1386|Bacillus 91061|Bacilli S NMT1-like family - - - ko:K07080 - - - - ko00000 - - - NMT1_3 k141_20881_1 218284.CCDN010000001_gene996 7.16e-24 97.8 COG4129@1|root,COG4129@2|Bacteria,1TP2T@1239|Firmicutes,4HAWV@91061|Bacilli,1ZBBI@1386|Bacillus 91061|Bacilli S Putative aromatic acid exporter C-terminal domain yqjA - - - - - - - - - - - ArAE_1,ArAE_1_C k141_36261_3 1485545.JQLW01000010_gene1517 8.08e-140 402.0 COG3440@1|root,COG3440@2|Bacteria 2|Bacteria V regulation of methylation-dependent chromatin silencing - - - ko:K07454 - - - - ko00000 - - - HNH,HNH_2,SAD_SRA k141_36261_4 207954.MED92_00155 6.44e-52 169.0 COG0454@1|root,COG0456@2|Bacteria,1QK43@1224|Proteobacteria,1SE0G@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Acetyltransferase (GNAT) domain - - - - - - - - - - - - - k141_37663_1 1033743.CAES01000041_gene82 9.7e-64 204.0 COG0225@1|root,COG0229@1|root,COG0225@2|Bacteria,COG0229@2|Bacteria,1TQ3E@1239|Firmicutes,4HAIV@91061|Bacilli,26RB2@186822|Paenibacillaceae 91061|Bacilli O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine msrB - 1.8.4.11,1.8.4.12 ko:K12267 - - - - ko00000,ko01000 - - - PMSR,SelR k141_12988_1 1116375.VEJY3_12635 7.57e-56 177.0 COG3153@1|root,COG3153@2|Bacteria,1RA42@1224|Proteobacteria,1S2G0@1236|Gammaproteobacteria,1XWYS@135623|Vibrionales 135623|Vibrionales S Acetyltransferase yhbS - - ko:K03824 - - - - ko00000,ko01000 - - - Acetyltransf_1,Acetyltransf_7,Acetyltransf_9 k141_2010_1 218284.CCDN010000005_gene3420 2.31e-173 489.0 COG1252@1|root,COG1252@2|Bacteria,1TPE6@1239|Firmicutes,4H9MY@91061|Bacilli,1ZC0V@1386|Bacillus 91061|Bacilli C NADH dehydrogenase yutJ - 1.6.99.3 ko:K03885 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - Pyr_redox_2 k141_2010_2 471223.GWCH70_2892 1.93e-52 167.0 COG4837@1|root,COG4837@2|Bacteria,1VA2D@1239|Firmicutes,4HKZN@91061|Bacilli,1WGMH@129337|Geobacillus 91061|Bacilli S Protein of unknown function (DUF1462) yuzD - - - - - - - - - - - DUF1462 k141_17456_2 1423755.BAML01000008_gene710 1.4e-08 55.5 COG1476@1|root,COG1476@2|Bacteria,1VEKB@1239|Firmicutes 1239|Firmicutes K Transcriptional - - - - - - - - - - - - HTH_3 k141_20064_1 1132442.KB889752_gene2541 2.83e-06 45.4 2EG8N@1|root,33A0G@2|Bacteria,1VMHK@1239|Firmicutes,4HSIH@91061|Bacilli,1ZJWT@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_28083_1 1453501.JELR01000002_gene990 4.27e-30 113.0 COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,1RMJJ@1236|Gammaproteobacteria,466SZ@72275|Alteromonadaceae 1236|Gammaproteobacteria KT COG3279 Response regulator of the LytR AlgR family algR - - ko:K08083 ko02020,map02020 M00493 - - ko00000,ko00001,ko00002,ko02022 - - - LytTR,Response_reg k141_28083_2 1206777.B195_21650 2.56e-12 69.7 COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,1RNB7@1236|Gammaproteobacteria 1236|Gammaproteobacteria S metal-dependent hydrolase with the TIM-barrel fold nfdA - - - - - - - - - - - Amidohydro_3 k141_34262_1 926556.Echvi_3469 4.41e-37 136.0 COG0457@1|root,COG0457@2|Bacteria,4P246@976|Bacteroidetes,47PGN@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF2911) - - - - - - - - - - - - DUF2911 k141_21021_1 218284.CCDN010000005_gene3249 3.13e-104 312.0 COG1175@1|root,COG1175@2|Bacteria,1TR2A@1239|Firmicutes,4HB8H@91061|Bacilli,1ZBHD@1386|Bacillus 91061|Bacilli P COG1175 ABC-type sugar transport systems, permease components malC GO:0003674,GO:0003824,GO:0005215,GO:0005363,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015154,GO:0015157,GO:0015399,GO:0015405,GO:0015422,GO:0015423,GO:0015766,GO:0015768,GO:0015772,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0032991,GO:0034219,GO:0042623,GO:0042626,GO:0043190,GO:0043211,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990060,GO:1990351 - ko:K15771 ko02010,map02010 M00491 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.16,3.A.1.1.2 - iYO844.BSU34150 BPD_transp_1 k141_17457_1 279010.BL00982 4.9e-14 75.5 COG2369@1|root,COG2369@2|Bacteria,1V2JT@1239|Firmicutes,4HFSR@91061|Bacilli,1ZIIA@1386|Bacillus 91061|Bacilli S Phage Mu protein F like protein - - - - - - - - - - - - Phage_Mu_F k141_24774_1 1453501.JELR01000001_gene3030 6.24e-68 231.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,464Y3@72275|Alteromonadaceae 1236|Gammaproteobacteria T GGDEF domain - - - - - - - - - - - - EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9 k141_11849_2 1286631.X805_28630 2.28e-20 91.7 COG1752@1|root,COG4775@1|root,COG1752@2|Bacteria,COG4775@2|Bacteria,1MUM9@1224|Proteobacteria,2VJRI@28216|Betaproteobacteria,1KJVX@119065|unclassified Burkholderiales 28216|Betaproteobacteria M Patatin-like phospholipase - - - ko:K07001 - - - - ko00000 - - - Bac_surface_Ag,POTRA,Patatin k141_37664_1 218284.CCDN010000002_gene2579 6.43e-128 369.0 COG1284@1|root,COG1284@2|Bacteria,1TQTP@1239|Firmicutes,4HBV2@91061|Bacilli,1ZCF3@1386|Bacillus 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2179) - - - - - - - - - - - - DUF2179,YitT_membrane k141_7104_1 1347086.CCBA010000027_gene3519 2.24e-132 386.0 COG2182@1|root,COG2182@2|Bacteria,1TPU9@1239|Firmicutes,4HBHE@91061|Bacilli,1ZBWG@1386|Bacillus 91061|Bacilli G COG2182 Maltose-binding periplasmic proteins domains cycB - - ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 M00207,M00491,M00599 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.16,3.A.1.1.2,3.A.1.1.38 - - SBP_bac_8 k141_22478_1 1294265.JCM21738_629 1.7e-40 139.0 COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,4HB1W@91061|Bacilli,1ZBYH@1386|Bacillus 91061|Bacilli E Belongs to the UPF0758 family radC - - ko:K03630 - - - - ko00000 - - - RadC k141_20065_1 545264.KB898750_gene346 3.68e-74 246.0 COG4772@1|root,COG4772@2|Bacteria,1MWDG@1224|Proteobacteria,1RQA5@1236|Gammaproteobacteria 1236|Gammaproteobacteria P receptor fecA - - ko:K16091 - - - - ko00000,ko02000 1.B.14.1.14 - - Plug,TonB_dep_Rec k141_29471_2 1042377.AFPJ01000034_gene2322 1.67e-07 51.2 COG3028@1|root,COG3028@2|Bacteria,1MZ4R@1224|Proteobacteria,1S9JJ@1236|Gammaproteobacteria,467RH@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the UPF0307 family yjgA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K09889 - - - - ko00000,ko03009 - - - DUF615 k141_2011_1 489825.LYNGBM3L_45830 3.63e-57 196.0 COG3379@1|root,COG3379@2|Bacteria,1G1KP@1117|Cyanobacteria,1H87X@1150|Oscillatoriales 1117|Cyanobacteria S type I phosphodiesterase nucleotide pyrophosphatase - - - - - - - - - - - - Phosphodiest k141_28084_1 41431.PCC8801_3686 5.97e-05 51.2 COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,3KJ4W@43988|Cyanothece 1117|Cyanobacteria Q TIGRFAM amino acid adenylation domain protein - - - - - - - - - - - - AMP-binding,AMP-binding_C,Condensation,PP-binding,PilZ,Thioesterase k141_10495_1 1453501.JELR01000002_gene55 1.78e-188 568.0 COG2911@1|root,COG2911@2|Bacteria,1MUVD@1224|Proteobacteria 1224|Proteobacteria M Protein conserved in bacteria tamB - - ko:K09800 - - - - ko00000,ko02000 - - - TamB k141_10495_2 1240350.AMZE01000004_gene2440 1.6e-17 84.3 COG2068@1|root,COG2068@2|Bacteria,1MW0X@1224|Proteobacteria,1S9Q1@1236|Gammaproteobacteria,1YVP8@136845|Pseudomonas putida group 1236|Gammaproteobacteria S MobA-like NTP transferase domain - - 2.7.7.76 ko:K07141 ko00790,map00790 - R11582 - ko00000,ko00001,ko01000 - - - NTP_transf_3 k141_11850_1 1294265.JCM21738_4601 6.32e-113 325.0 COG3880@1|root,COG3880@2|Bacteria,1V6YM@1239|Firmicutes,4HH4R@91061|Bacilli,1ZG9T@1386|Bacillus 91061|Bacilli S protein with conserved CXXC pairs mcsA GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 - ko:K19411 - - - - ko00000 - - - UVR k141_7105_1 1246484.D479_17329 3.37e-24 100.0 2FB9D@1|root,343FH@2|Bacteria,1W0QC@1239|Firmicutes,4HYWZ@91061|Bacilli,3NFN6@45667|Halobacillus 91061|Bacilli S Phosphotransferase enzyme family - - - - - - - - - - - - APH k141_7105_2 1385514.N782_01660 1.11e-27 107.0 arCOG10603@1|root,32SV6@2|Bacteria,1V1HA@1239|Firmicutes,4HFU1@91061|Bacilli,2YAM6@289201|Pontibacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_32987_1 1116375.VEJY3_12430 9.81e-167 471.0 COG1609@1|root,COG1609@2|Bacteria,1MU1G@1224|Proteobacteria,1RMSP@1236|Gammaproteobacteria,1XTZQ@135623|Vibrionales 135623|Vibrionales K transcriptional regulators galR - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 k141_32987_2 1280001.BAOA01000061_gene4482 1.66e-116 335.0 COG3703@1|root,COG3703@2|Bacteria,1RDNV@1224|Proteobacteria,1SC4B@1236|Gammaproteobacteria,1XUKZ@135623|Vibrionales 135623|Vibrionales P Gamma-glutamyl cyclotransferase, AIG2-like VV2631 - - - - - - - - - - - GGACT k141_32987_3 223926.28807388 2.25e-265 729.0 COG3213@1|root,COG3213@2|Bacteria,1MUJK@1224|Proteobacteria,1S0J0@1236|Gammaproteobacteria,1XUSM@135623|Vibrionales 135623|Vibrionales P involved in response to NO - - - ko:K07234 - - - - ko00000 - - - NnrS k141_32987_4 1116375.VEJY3_12410 1.94e-217 601.0 COG0598@1|root,COG0598@2|Bacteria,1MW8W@1224|Proteobacteria,1RRTZ@1236|Gammaproteobacteria,1XSI8@135623|Vibrionales 135623|Vibrionales P COG0598 Mg2 and Co2 transporters - - - ko:K16074 - - - - ko00000,ko02000 1.A.35.4 - - CorA k141_32987_5 223926.28807386 0.0 905.0 COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,1RMGP@1236|Gammaproteobacteria,1XSTC@135623|Vibrionales 135623|Vibrionales C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family glpD - 1.1.5.3 ko:K00111 ko00564,ko01110,map00564,map01110 - R00848 RC00029 ko00000,ko00001,ko01000 - - - DAO,DAO_C k141_32987_6 674977.VMC_24160 1.86e-124 367.0 COG0554@1|root,COG0554@2|Bacteria,1MUP7@1224|Proteobacteria,1RMAF@1236|Gammaproteobacteria,1XUKJ@135623|Vibrionales 135623|Vibrionales F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate glpK GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 - R00847 RC00002,RC00017 ko00000,ko00001,ko01000,ko04147 - - - FGGY_C,FGGY_N k141_17459_1 743720.Psefu_0325 2.94e-20 96.3 COG0643@1|root,COG0784@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1YVSH@136845|Pseudomonas putida group 1236|Gammaproteobacteria T Signal transduction histidine kinase chpA - - ko:K02487,ko:K06596 ko02020,ko02025,map02020,map02025 M00507 - - ko00000,ko00001,ko00002,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg k141_1104_1 926550.CLDAP_27060 2.83e-75 253.0 COG0366@1|root,COG4733@1|root,COG0366@2|Bacteria,COG4733@2|Bacteria,2G7WY@200795|Chloroflexi 200795|Chloroflexi G Belongs to the glycosyl hydrolase 13 family - - - - - - - - - - - - Alpha-amylase,CBM_20,fn3 k141_2012_1 1122194.AUHU01000003_gene2118 4.64e-62 204.0 COG0624@1|root,COG0624@2|Bacteria,1MVUX@1224|Proteobacteria,1RPPD@1236|Gammaproteobacteria,4656D@72275|Alteromonadaceae 1236|Gammaproteobacteria E allantoate amidohydrolase amaB - 3.5.3.9 ko:K02083 ko00230,ko01120,map00230,map01120 - R02423 RC00064 ko00000,ko00001,ko01000,ko01002 - - iPC815.YPO3249 M20_dimer,OHCU_decarbox,Peptidase_M20,Peptidase_M28 k141_11851_1 1347368.HG964412_gene7683 2.04e-09 57.8 COG1232@1|root,COG1232@2|Bacteria,1TQ6W@1239|Firmicutes,4HAUG@91061|Bacilli,1ZANK@1386|Bacillus 91061|Bacilli H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX hemG - 1.3.3.15,1.3.3.4 ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03222,R04178 RC00885 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS09325 Amino_oxidase k141_11851_2 1298598.JCM21714_1888 6.65e-32 117.0 2E4BW@1|root,32Z7G@2|Bacteria,1VH0F@1239|Firmicutes,4HPQD@91061|Bacilli,4716D@74385|Gracilibacillus 91061|Bacilli S Protein of unknown function (DUF2512) yndM - - - - - - - - - - - DUF2512 k141_21023_1 316278.SynRCC307_0149 1.96e-46 170.0 COG2192@1|root,COG2192@2|Bacteria,1G1FV@1117|Cyanobacteria,1H2J3@1129|Synechococcus 1117|Cyanobacteria O Carbamoyltransferase C-terminus - - - ko:K00612 - - - - ko00000,ko01000 - - - Carbam_trans_C,Carbam_trans_N k141_16395_1 1191299.AJYX01000109_gene3266 1.28e-207 576.0 COG3547@1|root,COG3547@2|Bacteria,1MXKJ@1224|Proteobacteria,1RSCP@1236|Gammaproteobacteria,1XUHK@135623|Vibrionales 135623|Vibrionales L Transposase IS116/IS110/IS902 family - - - ko:K07486 - - - - ko00000 - - - DEDD_Tnp_IS110,Transposase_20 k141_16395_3 399739.Pmen_2943 2.96e-31 129.0 COG0639@1|root,COG0639@2|Bacteria,1QE1Y@1224|Proteobacteria,1RRG9@1236|Gammaproteobacteria,1YDJ9@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria T Calcineurin-like phosphoesterase - - - - - - - - - - - - Metallophos k141_7107_1 1294265.JCM21738_2877 2.89e-126 368.0 COG0477@1|root,COG0477@2|Bacteria,1TTC8@1239|Firmicutes,4HAPZ@91061|Bacilli,1ZAQ7@1386|Bacillus 91061|Bacilli EGP Major facilitator superfamily yqgE - - ko:K08222 - - - - ko00000,ko02000 2.A.1.33 - - MFS_1 k141_37666_1 218284.CCDN010000001_gene268 2.75e-44 151.0 COG1612@1|root,COG1612@2|Bacteria,1U25B@1239|Firmicutes,4IBP3@91061|Bacilli,1ZMTJ@1386|Bacillus 91061|Bacilli O Cytochrome oxidase assembly protein - - - - - - - - - - - - COX15-CtaA k141_37666_2 218284.CCDN010000001_gene269 1.19e-07 51.2 COG0640@1|root,COG0640@2|Bacteria,1VA6G@1239|Firmicutes,4HKYT@91061|Bacilli,1ZGXI@1386|Bacillus 91061|Bacilli K transcriptional czrA - - ko:K22043 - - - - ko00000,ko03000 - - - HTH_5 k141_17461_1 1382358.JHVN01000014_gene1594 1.21e-106 330.0 COG0501@1|root,COG0501@2|Bacteria,1VP7M@1239|Firmicutes,4HSBS@91061|Bacilli 91061|Bacilli O Peptidase family M48 - - - - - - - - - - - - Peptidase_M48 k141_32988_1 1307436.PBF_18629 1.12e-101 298.0 COG2208@1|root,COG2208@2|Bacteria,1V0BN@1239|Firmicutes,4HECS@91061|Bacilli,1ZEVQ@1386|Bacillus 91061|Bacilli KT Sigma factor PP2C-like phosphatases rsbX GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0050896 3.1.3.3 ko:K05518 - - - - ko00000,ko01000,ko03021 - - - PP2C_2,SpoIIE k141_35549_1 1280001.BAOA01000073_gene3303 9.86e-21 82.8 2AWX4@1|root,31NUN@2|Bacteria,1QKIA@1224|Proteobacteria,1TINI@1236|Gammaproteobacteria,1XZDH@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_35549_2 1116375.VEJY3_08055 5.75e-131 376.0 2AX9W@1|root,31P8X@2|Bacteria,1QJEF@1224|Proteobacteria,1THDS@1236|Gammaproteobacteria,1XUGM@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_35549_3 1380391.JIAS01000011_gene5516 2.03e-101 308.0 COG2355@1|root,COG2355@2|Bacteria,1MWEW@1224|Proteobacteria,2TR5C@28211|Alphaproteobacteria,2JQWB@204441|Rhodospirillales 204441|Rhodospirillales E Membrane dipeptidase (Peptidase family M19) - - 3.4.13.19 ko:K01273 - - - - ko00000,ko00537,ko01000,ko01002,ko04147 - - - Peptidase_M19 k141_35549_4 1211115.ALIQ01000185_gene3143 2.68e-89 280.0 COG0747@1|root,COG0747@2|Bacteria,1MWR7@1224|Proteobacteria,2TS51@28211|Alphaproteobacteria 28211|Alphaproteobacteria E ABC-type dipeptide transport system periplasmic component dppAch3 - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 k141_20067_1 1453501.JELR01000001_gene2062 9.82e-73 237.0 COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,1RNQ2@1236|Gammaproteobacteria,4640F@72275|Alteromonadaceae 1236|Gammaproteobacteria GM nucleoside-diphosphate sugar epimerases wbpM - - - - - - - - - - - CoA_binding_3,Polysacc_synt_2 k141_20067_2 1123392.AQWL01000001_gene1562 1.62e-42 151.0 COG0472@1|root,COG0472@2|Bacteria,1MWYW@1224|Proteobacteria,2VNAG@28216|Betaproteobacteria,1KS1C@119069|Hydrogenophilales 119069|Hydrogenophilales M Glycosyl transferase family 4 - - - - - - - - - - - - Glycos_transf_4 k141_17462_1 218284.CCDN010000002_gene2219 1.98e-103 311.0 COG1017@1|root,COG1018@1|root,COG1017@2|Bacteria,COG1018@2|Bacteria,1TRG2@1239|Firmicutes,4HAU3@91061|Bacilli,1ZAP9@1386|Bacillus 91061|Bacilli C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress hmp GO:0000166,GO:0001505,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008941,GO:0009056,GO:0009987,GO:0016491,GO:0016705,GO:0016708,GO:0017144,GO:0033554,GO:0034641,GO:0036094,GO:0042133,GO:0042135,GO:0042737,GO:0043167,GO:0043168,GO:0044237,GO:0044248,GO:0044270,GO:0044464,GO:0046209,GO:0046210,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051213,GO:0051409,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0071500,GO:0071949,GO:0072593,GO:0097159,GO:1901265,GO:1901363,GO:2001057 1.14.12.17,1.18.1.3 ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 M00538 R02550,R03562,R05666,R09513 RC00269,RC00490,RC02556 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_6,Globin,NAD_binding_1 k141_26091_2 291985.CCSI01000001_gene2290 5.51e-35 128.0 COG3739@1|root,COG3739@2|Bacteria,1PMEC@1224|Proteobacteria,2TRGD@28211|Alphaproteobacteria,2K29P@204457|Sphingomonadales 204457|Sphingomonadales S Integral membrane protein - - - - - - - - - - - - DUF817 k141_5821_1 1219076.N646_3269 5.53e-20 82.4 2AWDN@1|root,31N9N@2|Bacteria,1QK0U@1224|Proteobacteria,1TI3C@1236|Gammaproteobacteria,1XYA9@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_5821_2 796620.VIBC2010_03942 2.48e-71 216.0 COG1516@1|root,COG1516@2|Bacteria,1MZ3G@1224|Proteobacteria,1S9BC@1236|Gammaproteobacteria,1XXKX@135623|Vibrionales 135623|Vibrionales N Flagellar protein FliS fliS - - ko:K02422 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FliS k141_5821_3 945543.VIBR0546_21550 6.02e-217 610.0 COG1345@1|root,COG1345@2|Bacteria,1MUVP@1224|Proteobacteria,1S11E@1236|Gammaproteobacteria,1XUTC@135623|Vibrionales 135623|Vibrionales N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end - GO:0005575,GO:0005576,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - ko:K02407 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flagellin_IN,FliD_C,FliD_N k141_5821_4 1190603.AJYD01000070_gene2305 2.82e-151 431.0 COG1344@1|root,COG1344@2|Bacteria,1MV1N@1224|Proteobacteria,1RN0Y@1236|Gammaproteobacteria,1Y2KM@135623|Vibrionales 135623|Vibrionales N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella - - - - - - - - - - - - Flagellin_C,Flagellin_N k141_5821_5 675814.VIC_004737 6.77e-133 383.0 2AVQP@1|root,31MHW@2|Bacteria,1QJD4@1224|Proteobacteria,1THC9@1236|Gammaproteobacteria,1XTN0@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - EAL k141_5821_6 945543.VIBR0546_21565 0.0 1206.0 COG1298@1|root,COG1298@2|Bacteria,1MUF3@1224|Proteobacteria,1RMSM@1236|Gammaproteobacteria,1XSP7@135623|Vibrionales 135623|Vibrionales N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin - - - ko:K02400 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 - - FHIPEP k141_5821_7 675814.VIC_004735 4.16e-210 587.0 COG1377@1|root,COG1377@2|Bacteria,1MUWI@1224|Proteobacteria,1RMHA@1236|Gammaproteobacteria,1XUUD@135623|Vibrionales 135623|Vibrionales N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin - - - ko:K02401 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - Bac_export_2 k141_5821_8 1280001.BAOA01000050_gene1385 6.53e-144 410.0 COG1684@1|root,COG1684@2|Bacteria,1RCGV@1224|Proteobacteria,1S2MW@1236|Gammaproteobacteria,1XVTR@135623|Vibrionales 135623|Vibrionales N Role in flagellar biosynthesis - - - ko:K02421 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - Bac_export_1 k141_5821_9 945543.VIBR0546_21580 1.76e-46 150.0 COG1987@1|root,COG1987@2|Bacteria,1N73W@1224|Proteobacteria,1SCBG@1236|Gammaproteobacteria,1XXWA@135623|Vibrionales 135623|Vibrionales N Role in flagellar biosynthesis - - - ko:K02420 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - Bac_export_3 k141_5821_10 223926.28809944 1.79e-138 396.0 COG1338@1|root,COG1338@2|Bacteria,1MVBU@1224|Proteobacteria,1RMYH@1236|Gammaproteobacteria,1XV0T@135623|Vibrionales 135623|Vibrionales N Plays a role in the flagellum-specific transport system - - - ko:K02419 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - FliP k141_5821_11 1219076.N646_3259 2.64e-52 167.0 COG1886@1|root,COG1886@2|Bacteria,1N815@1224|Proteobacteria,1SEUM@1236|Gammaproteobacteria,1XXZG@135623|Vibrionales 135623|Vibrionales N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation - - - ko:K02417 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 - - FliMN_C k141_5821_12 223926.28809942 7.93e-101 302.0 COG1868@1|root,COG1868@2|Bacteria,1NKVA@1224|Proteobacteria,1SGRG@1236|Gammaproteobacteria,1XUVR@135623|Vibrionales 135623|Vibrionales N Type III flagellar switch regulator (C-ring) FliN C-term - - - - - - - - - - - - FliMN_C k141_15131_2 35703.DQ02_14100 7.05e-69 231.0 COG0582@1|root,COG0582@2|Bacteria,1MVZB@1224|Proteobacteria,1RP4Y@1236|Gammaproteobacteria,3WX7M@544|Citrobacter 1236|Gammaproteobacteria L Phage integrase family intR - - ko:K14059 - - - - ko00000 - - - Arm-DNA-bind_2,Phage_integrase k141_28087_1 1121938.AUDY01000006_gene3092 1.26e-42 143.0 COG2919@1|root,COG2919@2|Bacteria,1VKC5@1239|Firmicutes,4HR53@91061|Bacilli,3NEXK@45667|Halobacillus 91061|Bacilli D Septum formation initiator divIC - - ko:K13052 - - - - ko00000,ko03036 - - - DivIC k141_35550_1 765912.Thimo_2007 1.42e-119 357.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPWS@1236|Gammaproteobacteria,1WWTW@135613|Chromatiales 135613|Chromatiales S ABC transporter - - - - - - - - - - - - ABC_tran,ABC_tran_Xtn k141_11853_9 1279017.AQYJ01000028_gene2148 0.0 1106.0 COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,1RMZ8@1236|Gammaproteobacteria,465MP@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1024 Enoyl-CoA hydratase carnithine racemase fadJ - 1.1.1.35,4.2.1.17,5.1.2.3 ko:K01782 ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212 M00032,M00087 R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094 RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 - - - 3HCDH,3HCDH_N,ECH_1 k141_11853_10 1279017.AQYJ01000028_gene2147 2.22e-243 672.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RPGB@1236|Gammaproteobacteria,464X4@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1960 Acyl-CoA dehydrogenases - - 1.3.8.7 ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_11853_11 1279017.AQYJ01000028_gene2146 1.61e-176 504.0 COG1804@1|root,COG1804@2|Bacteria,1MW1H@1224|Proteobacteria,1RN9B@1236|Gammaproteobacteria,46AHI@72275|Alteromonadaceae 1236|Gammaproteobacteria C acyl-CoA transferases carnitine dehydratase - - - - - - - - - - - - CoA_transf_3 k141_11853_12 1042377.AFPJ01000054_gene1692 7.13e-204 577.0 COG0415@1|root,COG0415@2|Bacteria,1MWRT@1224|Proteobacteria,1RN1P@1236|Gammaproteobacteria,465QF@72275|Alteromonadaceae 1236|Gammaproteobacteria L Belongs to the DNA photolyase family cry GO:0003674,GO:0003824,GO:0003904,GO:0003913,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 4.1.99.3 ko:K01669 - - - - ko00000,ko01000,ko03400 - - - DNA_photolyase,FAD_binding_7 k141_16423_1 323261.Noc_1562 3.91e-54 176.0 COG0454@1|root,COG0456@2|Bacteria,1RHB7@1224|Proteobacteria,1S3TD@1236|Gammaproteobacteria,1WZ5V@135613|Chromatiales 135613|Chromatiales K L-2,4-diaminobutyric acid acetyltransferase - - 2.3.1.178 ko:K06718 ko00260,ko01100,ko01120,map00260,map01100,map01120 M00033 R06978 RC00004,RC00096 ko00000,ko00001,ko00002,ko01000 - - - Acetyltransf_1 k141_16423_2 472759.Nhal_2707 7.18e-78 244.0 COG0160@1|root,COG0160@2|Bacteria,1MWY6@1224|Proteobacteria,1RQKU@1236|Gammaproteobacteria,1WXFB@135613|Chromatiales 135613|Chromatiales H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - 2.6.1.76 ko:K00836 ko00260,ko01100,ko01120,ko01210,ko01230,map00260,map01100,map01120,map01210,map01230 M00033 R06977 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 k141_4492_1 1453501.JELR01000002_gene1054 1.23e-25 104.0 COG2010@1|root,COG2010@2|Bacteria 2|Bacteria C Cytochrome c - - - ko:K17230 ko00920,ko01120,map00920,map01120 - R09499 - ko00000,ko00001 - - - Cytochrom_C,Cytochrome_CBB3,OmpA k141_3290_1 395493.BegalDRAFT_2711 6.22e-15 76.6 COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,1RMN5@1236|Gammaproteobacteria,460RT@72273|Thiotrichales 72273|Thiotrichales S Permease YjgP YjgQ - - - ko:K07091 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko02000 1.B.42.1 - - YjgP_YjgQ k141_29500_1 497964.CfE428DRAFT_3946 3.08e-12 67.0 2ECB6@1|root,3369I@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k141_20108_1 218284.CCDN010000001_gene169 3.06e-174 513.0 COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria,1TQXZ@1239|Firmicutes,4HB0B@91061|Bacilli,1ZDEG@1386|Bacillus 91061|Bacilli S von Willebrand factor type A domain - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - GATase1_like,VWA,VWA_2,VWA_3 k141_5850_1 305900.GV64_08325 1.27e-26 114.0 COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,1MVI9@1224|Proteobacteria,1RNB0@1236|Gammaproteobacteria,1XI0P@135619|Oceanospirillales 135619|Oceanospirillales D protein involved in exopolysaccharide biosynthesis - - - ko:K16554 ko05111,map05111 - - - ko00000,ko00001,ko02000 8.A.3.1 - - AAA_31,GNVR,Wzz k141_30435_1 1307436.PBF_04843 3.31e-92 278.0 COG0840@1|root,COG0840@2|Bacteria,1VTI2@1239|Firmicutes,4HV5F@91061|Bacilli,1ZQNP@1386|Bacillus 91061|Bacilli NT PAS fold - - - - - - - - - - - - MCPsignal,PAS_4,PAS_9 k141_35575_2 1177179.A11A3_08020 2.43e-72 220.0 COG3118@1|root,COG3118@2|Bacteria,1RHUA@1224|Proteobacteria,1S64W@1236|Gammaproteobacteria,1XK11@135619|Oceanospirillales 135619|Oceanospirillales O Thioredoxin - - 1.8.1.8 ko:K03672 - - - - ko00000,ko01000,ko03110 - - - Thioredoxin k141_35575_3 582744.Msip34_1933 3.77e-89 268.0 COG0500@1|root,COG0500@2|Bacteria,1RAE4@1224|Proteobacteria,2VQ27@28216|Betaproteobacteria,2KMPT@206350|Nitrosomonadales 206350|Nitrosomonadales Q Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family tpm - 2.1.1.67 ko:K00569 ko00983,map00983 - R08236,R08239,R08246 RC00003,RC00980,RC02277 ko00000,ko00001,ko01000 - - - TPMT k141_35575_4 686578.AFFX01000002_gene875 7.61e-43 142.0 COG2343@1|root,COG2343@2|Bacteria,1N1K4@1224|Proteobacteria,1SE87@1236|Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - NTP_transf_9 k141_35575_5 1123228.AUIH01000014_gene355 1.06e-57 195.0 COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,1RMCN@1236|Gammaproteobacteria,1XIC8@135619|Oceanospirillales 135619|Oceanospirillales P transporter antisigma-factor antagonist STAS - - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - STAS,Sulfate_transp k141_9492_2 1121943.KB899992_gene2186 3.52e-29 112.0 COG0697@1|root,COG0697@2|Bacteria 2|Bacteria EG spore germination - - - - - - - - - - - - EamA k141_37692_1 1116375.VEJY3_07485 1.78e-283 785.0 28M2E@1|root,2ZAGW@2|Bacteria,1R97D@1224|Proteobacteria,1RURR@1236|Gammaproteobacteria,1XVXB@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_24789_1 218284.CCDN010000007_gene3989 3.98e-182 513.0 COG0112@1|root,COG0112@2|Bacteria,1TQVM@1239|Firmicutes,4HA5K@91061|Bacilli,1ZB9V@1386|Bacillus 91061|Bacilli E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism glyA - 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 - - - SHMT k141_5851_1 397945.Aave_2307 2.45e-37 136.0 COG1711@1|root,COG1711@2|Bacteria,1RIA0@1224|Proteobacteria,2VIHJ@28216|Betaproteobacteria,4AB02@80864|Comamonadaceae 28216|Betaproteobacteria S Protein of unknown function (DUF3014) - - - - - - - - - - - - DUF3014 k141_16424_1 1122971.BAME01000081_gene5303 2.29e-31 123.0 COG0142@1|root,COG0142@2|Bacteria,4NET2@976|Bacteroidetes,2FMMI@200643|Bacteroidia,22WX7@171551|Porphyromonadaceae 976|Bacteroidetes H Belongs to the FPP GGPP synthase family - - 2.5.1.90 ko:K02523 ko00900,ko01110,map00900,map01110 - R09248 RC00279 ko00000,ko00001,ko01000,ko01006 - - - polyprenyl_synt k141_2401_2 218284.CCDN010000004_gene3062 2.52e-96 283.0 COG1238@1|root,COG1238@2|Bacteria,1V63I@1239|Firmicutes,4HHFZ@91061|Bacilli,1ZG20@1386|Bacillus 91061|Bacilli S SNARE associated Golgi protein - - - - - - - - - - - - SNARE_assoc k141_32111_1 218284.CCDN010000005_gene3426 2.35e-47 162.0 COG1252@1|root,COG1252@2|Bacteria,1TR6X@1239|Firmicutes,4HA14@91061|Bacilli,1ZAV9@1386|Bacillus 91061|Bacilli C NADH dehydrogenase yumB GO:0003674,GO:0003824,GO:0003955,GO:0006091,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0019646,GO:0022900,GO:0022904,GO:0044237,GO:0045333,GO:0055114 1.6.99.3 ko:K03885 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - iYO844.BSU32100 Pyr_redox_2 k141_28558_2 1279017.AQYJ01000024_gene1142 1.15e-201 559.0 COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,1RM7Y@1236|Gammaproteobacteria,4652M@72275|Alteromonadaceae 1236|Gammaproteobacteria C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit sucD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009361,GO:0009987,GO:0016310,GO:0019538,GO:0032991,GO:0036211,GO:0042709,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0046777,GO:0071704,GO:1901564,GO:1902494 6.2.1.5 ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - iE2348C_1286.E2348C_0608 CoA_binding,Ligase_CoA k141_28558_3 1453501.JELR01000002_gene89 6.08e-255 702.0 COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,1RMSU@1236|Gammaproteobacteria,46480@72275|Alteromonadaceae 1236|Gammaproteobacteria C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit sucC GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 6.2.1.5,6.2.1.9 ko:K01903,ko:K14067 ko00020,ko00630,ko00640,ko00660,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00630,map00640,map00660,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00346,M00374,M00620 R00405,R01256,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp_2,Ligase_CoA k141_22605_1 1116375.VEJY3_10115 1.82e-185 523.0 COG3487@1|root,COG3487@2|Bacteria,1MX5H@1224|Proteobacteria,1RPWE@1236|Gammaproteobacteria,1XVTP@135623|Vibrionales 135623|Vibrionales P Iron-regulated protein icmP - - ko:K07231 - - - - ko00000 - - - Peptidase_M75 k141_20221_1 218284.CCDN010000002_gene2290 1.5e-68 209.0 COG1380@1|root,COG1380@2|Bacteria,1VE19@1239|Firmicutes,4HMWP@91061|Bacilli,1ZQGW@1386|Bacillus 91061|Bacilli S LrgA family - - - ko:K06518 - - - - ko00000,ko02000 1.E.14.2 - - LrgA k141_20221_2 218284.CCDN010000002_gene2289 9.88e-97 286.0 COG1346@1|root,COG1346@2|Bacteria,1TRGN@1239|Firmicutes,4HF0M@91061|Bacilli,1ZFQ6@1386|Bacillus 91061|Bacilli M effector of murein hydrolase yxaC - - - - - - - - - - - LrgB k141_14283_2 224911.27356437 4.35e-63 197.0 COG3832@1|root,COG3832@2|Bacteria,1RDAM@1224|Proteobacteria,2U5ZG@28211|Alphaproteobacteria,3JY1T@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Activator of Hsp90 ATPase homolog 1-like protein - - - - - - - - - - - - AHSA1 k141_14283_3 314254.OA2633_05551 1.06e-60 198.0 COG1266@1|root,COG1266@2|Bacteria,1PV81@1224|Proteobacteria,2V6PS@28211|Alphaproteobacteria,43ZVU@69657|Hyphomonadaceae 28211|Alphaproteobacteria S CAAX protease self-immunity - - - ko:K07052 - - - - ko00000 - - - Abi k141_25_1 1123279.ATUS01000001_gene2478 2.25e-41 146.0 28KE4@1|root,2ZA0D@2|Bacteria,1MXZT@1224|Proteobacteria,1RYV4@1236|Gammaproteobacteria,1J6JN@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_19043_1 1051646.VITU9109_21839 2.88e-25 109.0 COG4961@1|root,COG4961@2|Bacteria,1R58C@1224|Proteobacteria,1S1A4@1236|Gammaproteobacteria,1XWG5@135623|Vibrionales 135623|Vibrionales U Putative Flp pilus-assembly TadE/G-like - - - - - - - - - - - - Tad k141_2402_1 377629.TERTU_3249 1.3e-49 164.0 COG1443@1|root,COG1443@2|Bacteria,1R9YJ@1224|Proteobacteria,1S6ZT@1236|Gammaproteobacteria,2PPZ3@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria I NUDIX domain idi GO:0003674,GO:0003824,GO:0004452,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016853,GO:0016860,GO:0016863,GO:0019637,GO:0033554,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0046490,GO:0050896,GO:0051716,GO:0071704,GO:0090407,GO:1901576 5.3.3.2 ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095,M00096,M00364,M00365,M00366,M00367 R01123 RC00455 ko00000,ko00001,ko00002,ko01000 - - iECH74115_1262.ECH74115_4179,iECIAI1_1343.ECIAI1_3008,iECO103_1326.ECO103_3464,iECSP_1301.ECSP_3858,iECs_1301.ECs3761,iEcE24377_1341.EcE24377A_3215,iG2583_1286.G2583_3542,iSFV_1184.SFV_2937,iSF_1195.SF2875,iSFxv_1172.SFxv_3153,iSSON_1240.SSON_3042,iS_1188.S3074,iZ_1308.Z4227 NUDIX k141_33310_1 218284.CCDN010000001_gene1882 1.97e-149 439.0 COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,4H9Z3@91061|Bacilli,1ZB24@1386|Bacillus 91061|Bacilli J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction pnp GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 M00394 R00437,R00438,R00439,R00440 RC02795 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 - - - KH_1,PNPase,RNase_PH,RNase_PH_C,S1 k141_33310_2 218284.CCDN010000001_gene1881 1.39e-139 401.0 COG0726@1|root,COG0726@2|Bacteria,1TQ5M@1239|Firmicutes,4HAHC@91061|Bacilli,1ZC6V@1386|Bacillus 91061|Bacilli G Sporulation protein, polysaccharide deacetylase ylxY GO:0005575,GO:0016020 - - - - - - - - - - Polysacc_deac_1 k141_26181_1 218284.CCDN010000001_gene7 3.76e-124 363.0 COG0758@1|root,COG0758@2|Bacteria,1TPP7@1239|Firmicutes,4HGWM@91061|Bacilli,1ZBZ3@1386|Bacillus 91061|Bacilli LU Rossmann fold nucleotide-binding protein involved in DNA uptake dprA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0007154,GO:0008150,GO:0009292,GO:0009294,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0044424,GO:0044464,GO:0044764,GO:0050896,GO:0051704,GO:0051716,GO:0071496 - ko:K04096 - - - - ko00000 - - - DNA_processg_A k141_13101_1 1453501.JELR01000001_gene3271 3.11e-70 223.0 COG2267@1|root,COG2267@2|Bacteria,1R41P@1224|Proteobacteria,1T1IM@1236|Gammaproteobacteria,467KZ@72275|Alteromonadaceae 1236|Gammaproteobacteria I Serine aminopeptidase, S33 - - - - - - - - - - - - Abhydrolase_1 k141_13101_2 1279017.AQYJ01000022_gene2578 1.15e-69 224.0 COG0534@1|root,COG0534@2|Bacteria,1MVRV@1224|Proteobacteria,1RRDQ@1236|Gammaproteobacteria,46495@72275|Alteromonadaceae 1236|Gammaproteobacteria V COG0534 Na -driven multidrug efflux pump - - - - - - - - - - - - MatE k141_28559_1 218284.CCDN010000005_gene3440 1.08e-29 107.0 COG2050@1|root,COG2050@2|Bacteria,1V7G2@1239|Firmicutes,4HIIA@91061|Bacilli,1ZGY5@1386|Bacillus 91061|Bacilli Q protein, possibly involved in aromatic compounds catabolism yuxO - - - - - - - - - - - 4HBT k141_5973_1 218284.CCDN010000005_gene3380 2.44e-266 739.0 COG1164@1|root,COG1164@2|Bacteria,1TPV4@1239|Firmicutes,4HAJJ@91061|Bacilli,1ZD3W@1386|Bacillus 91061|Bacilli E oligoendopeptidase pepF - - - - - - - - - - - Peptidase_M3 k141_15486_1 1131730.BAVI_15411 1.78e-26 100.0 29HMR@1|root,304J1@2|Bacteria,1TWSW@1239|Firmicutes,4I5M0@91061|Bacilli,1ZJ8C@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_15486_3 218284.CCDN010000001_gene1242 1.03e-28 113.0 COG2340@1|root,COG2340@2|Bacteria,1V6GZ@1239|Firmicutes,4HJ21@91061|Bacilli,1ZDSK@1386|Bacillus 91061|Bacilli J protein with SCP PR1 domains ykwD - - - - - - - - - - - CAP k141_2403_1 1453501.JELR01000002_gene616 8.69e-87 260.0 COG2995@1|root,COG2995@2|Bacteria,1N2QU@1224|Proteobacteria,1S9RM@1236|Gammaproteobacteria,46CS5@72275|Alteromonadaceae 1236|Gammaproteobacteria S Paraquat-inducible protein A pqiA2 - - ko:K03808 - - - - ko00000 - - - PqiA k141_28560_2 218284.CCDN010000007_gene3967 6.39e-64 199.0 COG4821@1|root,COG4821@2|Bacteria,1VJUP@1239|Firmicutes,4HP1J@91061|Bacilli,1ZH7S@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF2529) ywjG - - - - - - - - - - - DUF2529 k141_35688_2 218284.CCDN010000007_gene3925 3.7e-162 454.0 COG2120@1|root,COG2120@2|Bacteria,1TPSJ@1239|Firmicutes,4HA2P@91061|Bacilli,1ZB3T@1386|Bacillus 91061|Bacilli S deacetylase bshB2 - - ko:K22135 - - - - ko00000,ko01000 - - - PIG-L k141_20222_1 406124.ACPC01000045_gene3975 7.9e-09 57.4 COG0635@1|root,COG0635@2|Bacteria,1TREM@1239|Firmicutes,4HC2D@91061|Bacilli,1ZCRB@1386|Bacillus 91061|Bacilli H coproporphyrinogen III oxidase hemZ - - - - - - - - - - - Radical_SAM k141_20222_2 1294265.JCM21738_2918 6.5e-79 241.0 COG0561@1|root,COG0561@2|Bacteria,1V2XI@1239|Firmicutes,4HG2U@91061|Bacilli,1ZB1F@1386|Bacillus 91061|Bacilli S hydrolases of the HAD superfamily yhaX - - - - - - - - - - - Hydrolase_3 k141_29735_1 218284.CCDN010000004_gene3023 2.99e-92 271.0 COG3091@1|root,COG3091@2|Bacteria,1V6NU@1239|Firmicutes,4HIHY@91061|Bacilli,1ZG8Y@1386|Bacillus 91061|Bacilli S Belongs to the SprT family ydcK - - ko:K03095 - - - - ko00000 - - - SprT-like,Zn_ribbon_SprT k141_21431_1 218284.CCDN010000001_gene1308 2.06e-109 331.0 COG0697@1|root,COG0697@2|Bacteria,1TP7K@1239|Firmicutes,4HAH1@91061|Bacilli,1ZBEF@1386|Bacillus 91061|Bacilli EG Spore germination protein gerAA_1 - - ko:K06295 - - - - ko00000 - - - GerA k141_7148_1 1123290.AUDQ01000012_gene1734 1.86e-90 283.0 COG0151@1|root,COG0151@2|Bacteria,1UR8C@1239|Firmicutes,4IS9W@91061|Bacilli 91061|Bacilli F Biotin carboxylase - - - - - - - - - - - - ATP-grasp_4 k141_32128_2 1211579.PP4_24610 5.99e-08 53.9 2E7NP@1|root,32T01@2|Bacteria,1N5UY@1224|Proteobacteria,1T0X9@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_30963_1 1444310.JANV01000096_gene3259 1.68e-98 300.0 COG0175@1|root,COG0175@2|Bacteria,1TPR6@1239|Firmicutes,4HA1N@91061|Bacilli,1ZFDY@1386|Bacillus 91061|Bacilli EH COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase) FAD synthetase and related enzymes - - - ko:K19170 - - - - ko00000,ko02048 - - - PAPS_reduct k141_13143_1 42565.FP66_10085 9.29e-38 138.0 COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,1RMUD@1236|Gammaproteobacteria,1XH7K@135619|Oceanospirillales 135619|Oceanospirillales C NADH-quinone oxidoreductase subunit F fdsB - - ko:K00124 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001 - - - Complex1_51K,NADH_4Fe-4S,SLBB k141_13143_2 42565.FP66_10090 1.6e-92 271.0 COG1905@1|root,COG1905@2|Bacteria,1RHBU@1224|Proteobacteria,1T09A@1236|Gammaproteobacteria,1XJMK@135619|Oceanospirillales 135619|Oceanospirillales C Thioredoxin-like [2Fe-2S] ferredoxin - - - ko:K00127 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001 - - - 2Fe-2S_thioredx k141_20244_1 218284.CCDN010000001_gene940 2.42e-107 319.0 COG0404@1|root,COG0404@2|Bacteria,1TRKX@1239|Firmicutes,4H9MX@91061|Bacilli,1ZAS5@1386|Bacillus 91061|Bacilli E The glycine cleavage system catalyzes the degradation of glycine gcvT - 2.1.2.10 ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 M00532 R01221,R02300,R04125 RC00022,RC00069,RC00183,RC02834 ko00000,ko00001,ko00002,ko01000 - - - GCV_T,GCV_T_C k141_2422_1 265729.GS18_0210000 2.51e-71 221.0 COG1595@1|root,COG1595@2|Bacteria,1VTV0@1239|Firmicutes,4HTC4@91061|Bacilli,1ZFY2@1386|Bacillus 91061|Bacilli K Belongs to the sigma-70 factor family. ECF subfamily sigY - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_2422_2 218284.CCDN010000005_gene3465 6.14e-46 149.0 2EPRF@1|root,33HBX@2|Bacteria,1VP6R@1239|Firmicutes,4HRWK@91061|Bacilli,1ZIF1@1386|Bacillus 91061|Bacilli S Required for proper spore morphogenesis. Important for spore germination ywcE GO:0008150,GO:0009847,GO:0032502 - - - - - - - - - - YwcE k141_15516_1 932213.SPM24T3_09896 3.18e-62 197.0 COG0765@1|root,COG0765@2|Bacteria,1PK66@1224|Proteobacteria,1S58X@1236|Gammaproteobacteria 1236|Gammaproteobacteria P amino acid ABC transporter - - - ko:K02029 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 k141_15516_2 371042.NG99_11140 1.22e-51 169.0 COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,1RMX1@1236|Gammaproteobacteria,3X716@551|Erwinia 1236|Gammaproteobacteria E RecF/RecN/SMC N terminal domain - - 3.6.3.21 ko:K02028,ko:K02029 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran k141_57_1 1294265.JCM21738_5443 4.3e-20 82.0 COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,4HF4R@91061|Bacilli,1ZGGZ@1386|Bacillus 91061|Bacilli L Reverse transcriptase (RNA-dependent DNA polymerase) - - - - - - - - - - - - GIIM,RVT_1 k141_6002_1 929556.Solca_1319 4.97e-07 53.1 COG1266@1|root,COG1266@2|Bacteria,4NPEG@976|Bacteroidetes,1IUFC@117747|Sphingobacteriia 976|Bacteroidetes S CAAX protease self-immunity - - - ko:K07052 - - - - ko00000 - - - Abi k141_6002_2 1042377.AFPJ01000004_gene359 1.04e-58 184.0 2EBHR@1|root,335I6@2|Bacteria,1N8W4@1224|Proteobacteria,1SG3V@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_14319_2 323850.Shew_0251 4.84e-127 364.0 COG0582@1|root,COG0582@2|Bacteria,1P1R9@1224|Proteobacteria,1RRV0@1236|Gammaproteobacteria,2QBF5@267890|Shewanellaceae 1236|Gammaproteobacteria L PFAM phage integrase family protein - - - - - - - - - - - - Phage_integrase k141_8391_1 218284.CCDN010000002_gene2017 2.73e-77 247.0 COG3227@1|root,COG3227@2|Bacteria,1TP08@1239|Firmicutes,4H9S6@91061|Bacilli,1ZCEP@1386|Bacillus 91061|Bacilli E Peptidase M4 npr GO:0005575,GO:0005576 3.4.24.28 ko:K01400 - - - - ko00000,ko01000,ko01002 - - - FTP,PepSY,Peptidase_M4,Peptidase_M4_C k141_10729_2 1453501.JELR01000002_gene930 1.41e-18 84.3 COG0860@1|root,COG0860@2|Bacteria,1MUQK@1224|Proteobacteria,1RMP1@1236|Gammaproteobacteria,4647N@72275|Alteromonadaceae 1236|Gammaproteobacteria M N-acetylmuramoyl-L-alanine amidase amiC - 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - AMIN,Amidase_3,LysM k141_15517_1 796606.BMMGA3_14530 1.33e-68 218.0 COG0598@1|root,COG0598@2|Bacteria,1TPSV@1239|Firmicutes,4HAPC@91061|Bacilli,1ZBVW@1386|Bacillus 91061|Bacilli P Mediates influx of magnesium ions corA GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - ko:K03284 - - - - ko00000,ko02000 1.A.35.1,1.A.35.3 - iYO844.BSU08000 CorA k141_7156_1 1285586.H131_19402 3.2e-82 248.0 COG0406@1|root,COG0406@2|Bacteria,1V3RC@1239|Firmicutes,4HHSJ@91061|Bacilli,3IY8N@400634|Lysinibacillus 91061|Bacilli G Phosphoglycerate mutase - - 5.4.2.11 ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - His_Phos_1 k141_11922_1 1294265.JCM21738_137 1.47e-124 359.0 COG1284@1|root,COG1284@2|Bacteria,1TRAU@1239|Firmicutes,4H9UY@91061|Bacilli,1ZBUC@1386|Bacillus 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2179) ypjC - - - - - - - - - - - DUF2179,YitT_membrane k141_13144_2 720555.BATR1942_03415 7.67e-08 53.5 2AP4C@1|root,31E5Z@2|Bacteria,1U9RE@1239|Firmicutes,4HSI2@91061|Bacilli,1ZJ77@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_29744_1 1453501.JELR01000001_gene2940 4.43e-126 374.0 COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,1RMD2@1236|Gammaproteobacteria,46508@72275|Alteromonadaceae 1236|Gammaproteobacteria E Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate alkJ - 1.1.99.1 ko:K00108 ko00260,ko01100,map00260,map01100 M00555 R01025 RC00087 ko00000,ko00001,ko00002,ko01000 - - - GMC_oxred_C,GMC_oxred_N k141_19063_1 218284.CCDN010000005_gene3329 6.32e-121 355.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4HASW@91061|Bacilli,1ZB29@1386|Bacillus 91061|Bacilli I Belongs to the thiolase family - - 2.3.1.16,2.3.1.9 ko:K00626,ko:K00632 ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00087,M00088,M00095,M00113,M00373,M00374,M00375 R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095 RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N k141_19063_2 218284.CCDN010000005_gene3328 1.4e-61 197.0 COG1960@1|root,COG1960@2|Bacteria,1TSN3@1239|Firmicutes,4HB0T@91061|Bacilli,1ZDR4@1386|Bacillus 91061|Bacilli I Acyl-CoA dehydrogenase, N-terminal domain - - 1.3.8.7 ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_30965_1 1453501.JELR01000002_gene1458 5.39e-103 301.0 COG1051@1|root,COG1051@2|Bacteria 2|Bacteria F GDP-mannose mannosyl hydrolase activity - - 2.1.3.15,6.4.1.2 ko:K01962,ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - NUDIX k141_36886_2 1279017.AQYJ01000027_gene1868 1.74e-104 302.0 29BPX@1|root,2ZYN9@2|Bacteria,1RF9J@1224|Proteobacteria,1S4CC@1236|Gammaproteobacteria,467QD@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF4265) - - - - - - - - - - - - DUF4265 k141_14320_2 218284.CCDN010000004_gene3026 6.84e-65 204.0 COG1191@1|root,COG1191@2|Bacteria,1TP3Q@1239|Firmicutes,4HBIW@91061|Bacilli,1ZBAP@1386|Bacillus 91061|Bacilli K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released sigB GO:0000988,GO:0000990,GO:0003674,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043254,GO:0043620,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - ko:K03090 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r3,Sigma70_r4 k141_9539_1 218284.CCDN010000008_gene4130 2.73e-102 330.0 COG0366@1|root,COG1523@1|root,COG5492@1|root,COG0366@2|Bacteria,COG1523@2|Bacteria,COG5492@2|Bacteria,1TP3M@1239|Firmicutes,4HBP5@91061|Bacilli,1ZC85@1386|Bacillus 91061|Bacilli G Belongs to the glycosyl hydrolase 13 family pulA2 - 3.2.1.1,3.2.1.41 ko:K01176,ko:K01200 ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973 - R02108,R02111,R02112,R11262 - ko00000,ko00001,ko01000 - CBM48,GH13 - Alpha-amylase,Big_2,CBM_48,G5,Gram_pos_anchor,PUD,SLH,YSIRK_signal k141_24997_1 33876.JNXY01000023_gene5181 5.48e-25 105.0 COG0520@1|root,COG0520@2|Bacteria,2I9H7@201174|Actinobacteria,4DFKP@85008|Micromonosporales 201174|Actinobacteria E Aminotransferase class-V - - - - - - - - - - - - Aminotran_5 k141_27370_1 218284.CCDN010000004_gene3052 4.05e-97 291.0 COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,4HG3V@91061|Bacilli,1ZFYF@1386|Bacillus 91061|Bacilli E ATPases associated with a variety of cellular activities - - 3.6.3.25,3.6.3.30 ko:K02010,ko:K02045 ko00920,ko02010,map00920,map02010 M00185,M00190 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.10,3.A.1.6.1,3.A.1.6.3 - - ABC_tran k141_27370_2 218284.CCDN010000004_gene3053 1.12e-138 397.0 COG1177@1|root,COG1177@2|Bacteria,1URBC@1239|Firmicutes,4HGPX@91061|Bacilli,1ZGC1@1386|Bacillus 91061|Bacilli E Binding-protein-dependent transport system inner membrane component - - - ko:K02053 ko02024,map02024 M00193 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11 - - BPD_transp_1 k141_27370_3 218284.CCDN010000004_gene3054 3.26e-32 119.0 COG1176@1|root,COG1176@2|Bacteria,1V1K7@1239|Firmicutes,4HG7A@91061|Bacilli,1ZGHA@1386|Bacillus 91061|Bacilli E transport system, permease component - - - ko:K02054 ko02024,map02024 M00193 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11 - - BPD_transp_1 k141_11923_1 218284.CCDN010000001_gene1081 7.95e-82 251.0 COG0789@1|root,COG5012@1|root,COG0789@2|Bacteria,COG5012@2|Bacteria,1TQXC@1239|Firmicutes,4HCSG@91061|Bacilli,1ZD8Q@1386|Bacillus 91061|Bacilli K MerR family transcriptional regulator ycgE - - ko:K22491 - - - - ko00000,ko03000 - - - B12-binding,B12-binding_2,MerR_1 k141_6004_1 1121943.KB900011_gene1119 7.5e-97 301.0 COG1629@1|root,COG4771@2|Bacteria,1MUPZ@1224|Proteobacteria,1RMMP@1236|Gammaproteobacteria,1XNN1@135619|Oceanospirillales 135619|Oceanospirillales P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec k141_36887_1 1150600.ADIARSV_4006 6.27e-21 92.4 COG2755@1|root,COG2755@2|Bacteria,4NNTP@976|Bacteroidetes,1IS2P@117747|Sphingobacteriia 976|Bacteroidetes E GDSL-like Lipase/Acylhydrolase family - - - - - - - - - - - - Acyltransferase,Lipase_GDSL_2,cNMP_binding k141_30966_1 665959.HMPREF1013_00239 1.84e-120 357.0 COG0621@1|root,COG0621@2|Bacteria,1TNYN@1239|Firmicutes,4HAAS@91061|Bacilli,1ZBMF@1386|Bacillus 91061|Bacilli J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine miaB GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035597,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360 2.8.4.3 ko:K06168 - - R10645,R10646,R10647 RC00003,RC00980,RC03221,RC03222 ko00000,ko01000,ko03016 - - - Radical_SAM,TRAM,UPF0004 k141_21446_1 1453501.JELR01000001_gene2224 4.03e-146 415.0 COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,1RMBB@1236|Gammaproteobacteria,46560@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) fabG GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0030497,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0048037,GO:0050661,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - iAF1260.b1093,iAPECO1_1312.APECO1_174,iBWG_1329.BWG_0941,iE2348C_1286.E2348C_1185,iEC55989_1330.EC55989_1205,iECABU_c1320.ECABU_c13060,iECDH10B_1368.ECDH10B_1165,iECDH1ME8569_1439.ECDH1ME8569_1028,iECED1_1282.ECED1_1236,iECIAI39_1322.ECIAI39_2068,iECNA114_1301.ECNA114_1150,iECO103_1326.ECO103_1138,iECOK1_1307.ECOK1_1200,iECP_1309.ECP_1085,iECS88_1305.ECS88_1107,iECSE_1348.ECSE_1157,iECSF_1327.ECSF_0992,iECUMN_1333.ECUMN_1268,iECW_1372.ECW_m1201,iEKO11_1354.EKO11_2741,iETEC_1333.ETEC_1158,iEcDH1_1363.EcDH1_2554,iEcE24377_1341.EcE24377A_1214,iEcHS_1320.EcHS_A1215,iEcSMS35_1347.EcSMS35_2034,iEcolC_1368.EcolC_2508,iG2583_1286.G2583_1353,iJN746.PP_1914,iJO1366.b1093,iJR904.b1093,iSBO_1134.SBO_1970,iSFV_1184.SFV_1113,iSF_1195.SF1097,iSFxv_1172.SFxv_1249,iSSON_1240.SSON_1113,iS_1188.S1177,iSbBS512_1146.SbBS512_E2231,iUMN146_1321.UM146_11860,iUMNK88_1353.UMNK88_1363,iUTI89_1310.UTI89_C1218,iWFL_1372.ECW_m1201,iY75_1357.Y75_RS05710 adh_short_C2 k141_7157_1 218284.CCDN010000006_gene3623 5.05e-136 418.0 COG0457@1|root,COG0457@2|Bacteria,1TSH7@1239|Firmicutes,4HACN@91061|Bacilli,1ZBDH@1386|Bacillus 91061|Bacilli M Tetratricopeptide repeat - - - - - - - - - - - - - k141_20246_1 501479.ACNW01000099_gene962 3.64e-63 207.0 COG3206@1|root,COG3206@2|Bacteria,1R7FS@1224|Proteobacteria,2VEXP@28211|Alphaproteobacteria 28211|Alphaproteobacteria M protein involved in exopolysaccharide biosynthesis - - - - - - - - - - - - Wzz k141_58_1 218284.CCDN010000001_gene1256 3.12e-192 537.0 COG2378@1|root,COG2378@2|Bacteria,1TSA2@1239|Firmicutes,4HCDN@91061|Bacilli,1ZD8Z@1386|Bacillus 91061|Bacilli K WYL domain - - - - - - - - - - - - WYL k141_58_2 218284.CCDN010000001_gene1257 2.67e-33 115.0 2DPPC@1|root,332VC@2|Bacteria,1VM0N@1239|Firmicutes,4HNHT@91061|Bacilli,1ZIVE@1386|Bacillus 91061|Bacilli S Phospholipase_D-nuclease N-terminal yxlE - - - - - - - - - - - PLDc_N k141_58_3 1229783.C273_05020 3.13e-08 55.8 COG1125@1|root,COG1125@2|Bacteria,1TPV8@1239|Firmicutes,4H9SI@91061|Bacilli,4GXAM@90964|Staphylococcaceae 91061|Bacilli E ATP-binding protein proV - - ko:K05847 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - ABC_tran k141_1206_1 315730.BcerKBAB4_3414 2.2e-20 100.0 COG0840@1|root,COG1196@1|root,COG0840@2|Bacteria,COG1196@2|Bacteria,1UHRW@1239|Firmicutes,4IS7R@91061|Bacilli,1ZS21@1386|Bacillus 91061|Bacilli NT nuclear chromosome segregation - - - - - - - - - - - - Peptidase_S74 k141_15519_2 935836.JAEL01000111_gene693 4.42e-81 244.0 COG0494@1|root,COG0494@2|Bacteria,1V6F5@1239|Firmicutes,4HII9@91061|Bacilli,1ZFIW@1386|Bacillus 91061|Bacilli L Belongs to the Nudix hydrolase family nudF - 3.6.1.13 ko:K01515 ko00230,map00230 - R01054 RC00002 ko00000,ko00001,ko01000 - - iSB619.SA_RS07540,iYO844.BSU23610 NUDIX k141_36888_1 391587.KAOT1_21192 7.83e-18 82.4 COG1090@1|root,COG1090@2|Bacteria,4NH8J@976|Bacteroidetes,1HXMJ@117743|Flavobacteriia 976|Bacteroidetes S epimerase - - - ko:K07071 - - - - ko00000 - - - DUF1731,Epimerase k141_35723_1 866895.HBHAL_1251 1.57e-25 103.0 COG0477@1|root,COG2814@2|Bacteria,1TQEW@1239|Firmicutes,4HASU@91061|Bacilli,3NDQ8@45667|Halobacillus 91061|Bacilli EGP Sugar (and other) transporter ymfD - - ko:K08221 - - - - ko00000,ko02000 2.A.1.32 - - MFS_1,MFS_2,Sugar_tr k141_35723_2 935837.JAEK01000007_gene3266 9.61e-65 210.0 COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,4H9SB@91061|Bacilli,1ZBAN@1386|Bacillus 91061|Bacilli S COG1253 Hemolysins and related proteins containing CBS domains yrkA - - - - - - - - - - - CBS,CorC_HlyC,DUF21 k141_22637_1 1116375.VEJY3_23701 0.0 947.0 COG0296@1|root,COG0296@2|Bacteria,1QTVN@1224|Proteobacteria,1RQSK@1236|Gammaproteobacteria,1XU7M@135623|Vibrionales 135623|Vibrionales G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position glgB GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901576 2.4.1.18 ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02110 - ko00000,ko00001,ko00002,ko01000,ko04147 - CBM48,GH13 - Alpha-amylase,Alpha-amylase_C,CBM_48 k141_22637_2 1116375.VEJY3_23696 9.89e-79 239.0 COG0744@1|root,COG0744@2|Bacteria,1RDAQ@1224|Proteobacteria,1RMGB@1236|Gammaproteobacteria,1XWFV@135623|Vibrionales 135623|Vibrionales M Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors mtgA - 2.4.1.129 ko:K03814 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly k141_26210_1 218284.CCDN010000007_gene3941 5.31e-113 325.0 COG3465@1|root,COG3465@2|Bacteria,1V6Q4@1239|Firmicutes,4HHX3@91061|Bacilli,1ZFMJ@1386|Bacillus 91061|Bacilli - - ywgA - - ko:K09388 - - - - ko00000 - - - - k141_13145_2 458817.Shal_1982 1.5e-77 238.0 2BN4A@1|root,32GR8@2|Bacteria,1RHQ4@1224|Proteobacteria,1S86P@1236|Gammaproteobacteria,2QBUM@267890|Shewanellaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_13145_3 1454004.AW11_02453 7.4e-22 91.7 COG2197@1|root,COG2197@2|Bacteria,1RH8D@1224|Proteobacteria,2WEH4@28216|Betaproteobacteria 28216|Betaproteobacteria K luxR family - - - - - - - - - - - - GerE,Response_reg k141_9540_1 218284.CCDN010000001_gene1925 1.02e-61 194.0 COG1843@1|root,COG1843@2|Bacteria,1VF85@1239|Firmicutes,4HNQK@91061|Bacilli,1ZI5S@1386|Bacillus 91061|Bacilli N Flagellar basal body rod modification protein flgD GO:0001539,GO:0005575,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009424,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588 - ko:K02389 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FlgD k141_9540_2 218284.CCDN010000001_gene1924 5.91e-50 162.0 2E35U@1|root,32Y5R@2|Bacteria,1VEH9@1239|Firmicutes,4HMCM@91061|Bacilli,1ZQS3@1386|Bacillus 91061|Bacilli N Putative flagellar flg - - - - - - - - - - - Flagellar_put k141_10731_1 1453501.JELR01000002_gene992 1.07e-36 134.0 COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,1RMA3@1236|Gammaproteobacteria,4644I@72275|Alteromonadaceae 1236|Gammaproteobacteria E argininosuccinate lyase argH GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01086 RC00445,RC00447 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ASL_C2,Lyase_1 k141_10731_2 1453501.JELR01000002_gene991 1.6e-63 207.0 COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,1RQDA@1236|Gammaproteobacteria,4666A@72275|Alteromonadaceae 1236|Gammaproteobacteria T signal transduction protein with a C-terminal ATPase domain algZ - 2.7.13.3 ko:K08082 ko02020,map02020 M00493 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - His_kinase k141_33333_2 218284.CCDN010000006_gene3649 1.55e-208 580.0 COG1493@1|root,COG1493@2|Bacteria,1TP5Z@1239|Firmicutes,4HAXR@91061|Bacilli,1ZD05@1386|Bacillus 91061|Bacilli F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion hprK GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K06023 - - - - ko00000,ko01000 - - - Hpr_kinase_C,Hpr_kinase_N k141_8392_1 1453501.JELR01000002_gene1412 2.01e-101 305.0 COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,1RNS6@1236|Gammaproteobacteria,4655Y@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide bioF GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.47 ko:K00652 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R03210,R10124 RC00004,RC00039,RC02725 ko00000,ko00001,ko00002,ko01000,ko01007 - - iEC55989_1330.EC55989_0819,iECO111_1330.ECO111_0837,iECO26_1355.ECO26_0902,iSDY_1059.SDY_0830 Aminotran_1_2 k141_8392_2 1042377.AFPJ01000043_gene849 5.62e-27 109.0 COG0500@1|root,COG1073@1|root,COG1073@2|Bacteria,COG2226@2|Bacteria,1PA5F@1224|Proteobacteria,1RY7A@1236|Gammaproteobacteria,465B1@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway bioC GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008757,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0010340,GO:0016053,GO:0016740,GO:0016741,GO:0016787,GO:0016788,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032259,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0052689,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.197 ko:K02169 ko00780,ko01100,map00780,map01100 M00572 R09543 RC00003,RC00460 ko00000,ko00001,ko00002,ko01000 - - iECP_1309.ECP_0791,iSBO_1134.SBO_0664,iSFV_1184.SFV_0760,iSF_1195.SF0727,iSFxv_1172.SFxv_0792,iSSON_1240.SSON_0756,iS_1188.S0768,iSbBS512_1146.SbBS512_E2575 Methyltransf_11 k141_29747_1 1453501.JELR01000002_gene1082 2.4e-66 216.0 COG0790@1|root,COG0790@2|Bacteria,1N4EV@1224|Proteobacteria,1SZKW@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Gram-negative bacterial TonB protein C-terminal - - - - - - - - - - - - Sel1,TonB_C k141_34517_2 1042377.AFPJ01000007_gene1783 1.29e-68 213.0 COG2834@1|root,COG2834@2|Bacteria,1PXDV@1224|Proteobacteria,1S9FW@1236|Gammaproteobacteria,46853@72275|Alteromonadaceae 1236|Gammaproteobacteria M Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) lolA GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0030288,GO:0030313,GO:0031975,GO:0032940,GO:0033036,GO:0034613,GO:0042597,GO:0042886,GO:0042953,GO:0042954,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0051641,GO:0070727,GO:0071702,GO:0071705,GO:0072321,GO:0072322,GO:0072323,GO:0072657 - ko:K03634 - - - - ko00000 - - - LolA k141_30968_2 218284.CCDN010000001_gene2 5.5e-78 244.0 COG1220@1|root,COG1220@2|Bacteria,1TPKQ@1239|Firmicutes,4HA83@91061|Bacilli,1ZCWK@1386|Bacillus 91061|Bacilli O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis hslU - - ko:K03667 - - - - ko00000,ko03110 - - - AAA_2,ClpB_D2-small k141_36889_1 314265.R2601_00235 7.11e-122 359.0 COG0747@1|root,COG0747@2|Bacteria,1MWGY@1224|Proteobacteria,2TR73@28211|Alphaproteobacteria 28211|Alphaproteobacteria E COG0747 ABC-type dipeptide transport system, periplasmic component appA - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 k141_14503_1 218284.CCDN010000001_gene1038 1.29e-120 349.0 COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,4HAEX@91061|Bacilli,1ZDBF@1386|Bacillus 91061|Bacilli L recombinase XerD xerD - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase k141_3833_2 502025.Hoch_5814 8.45e-27 101.0 COG4576@1|root,COG4576@2|Bacteria,1RIK4@1224|Proteobacteria,4362N@68525|delta/epsilon subdivisions,2X9F2@28221|Deltaproteobacteria,2Z246@29|Myxococcales 28221|Deltaproteobacteria CQ Ethanolamine utilisation protein EutN/carboxysome - - - - - - - - - - - - EutN_CcmL k141_3833_3 228405.HNE_1295 1.07e-28 107.0 COG0295@1|root,COG0295@2|Bacteria,1MY2R@1224|Proteobacteria,2U9FW@28211|Alphaproteobacteria 28211|Alphaproteobacteria F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis cdd - 3.5.4.5 ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R01878,R02485,R08221 RC00074,RC00514 ko00000,ko00001,ko01000 - - - dCMP_cyt_deam_1,dCMP_cyt_deam_2 k141_31179_2 218284.CCDN010000005_gene3335 2.66e-47 160.0 COG0208@1|root,COG0208@2|Bacteria,1TQTH@1239|Firmicutes,4H9WX@91061|Bacilli,1ZBBM@1386|Bacillus 91061|Bacilli F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdB - 1.17.4.1 ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_sm k141_25193_1 218284.CCDN010000001_gene518 2.35e-217 603.0 COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,4H9YE@91061|Bacilli,1ZBAY@1386|Bacillus 91061|Bacilli C Belongs to the citrate synthase family citZ - 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 - - - Citrate_synt k141_10883_1 218284.CCDN010000001_gene155 3.45e-198 553.0 COG1071@1|root,COG1071@2|Bacteria,1TQDG@1239|Firmicutes,4H9PQ@91061|Bacilli,1ZBE0@1386|Bacillus 91061|Bacilli C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit pdhA - 1.2.4.1 ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh k141_10883_2 279010.BL01617 1.21e-159 452.0 COG0022@1|root,COG0022@2|Bacteria,1TP3J@1239|Firmicutes,4HA4H@91061|Bacilli,1ZBJ1@1386|Bacillus 91061|Bacilli C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit pdhB - 1.2.4.1 ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS05355,iYO844.BSU14590 Transket_pyr,Transketolase_C k141_1378_1 218284.CCDN010000007_gene3841 2.53e-189 528.0 COG0042@1|root,COG0042@2|Bacteria,1TQ2R@1239|Firmicutes,4HA9K@91061|Bacilli,1ZBSF@1386|Bacillus 91061|Bacilli J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines dus - - - - - - - - - - - Dus k141_37023_2 1295642.H839_08129 1.01e-24 94.4 COG3655@1|root,COG3655@2|Bacteria 2|Bacteria K Transcriptional regulator - - - ko:K07727 - - - - ko00000,ko03000 - - - HTH_26,HTH_3 k141_316_1 1122194.AUHU01000006_gene551 7.49e-150 444.0 COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,1RNCM@1236|Gammaproteobacteria,464YW@72275|Alteromonadaceae 1236|Gammaproteobacteria C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - - - - - - - - - - Ald_Xan_dh_C2 k141_19208_1 283942.IL2597 6.89e-120 360.0 COG3868@1|root,COG3868@2|Bacteria,1PIK8@1224|Proteobacteria,1RZGT@1236|Gammaproteobacteria,2QGVN@267893|Idiomarinaceae 1236|Gammaproteobacteria S Glycoside-hydrolase family GH114 - - - - - - - - - - - - Glyco_hydro_114 k141_19208_2 1280001.BAOA01000177_gene2927 1.02e-62 193.0 COG0251@1|root,COG0251@2|Bacteria,1RDJX@1224|Proteobacteria,1THSN@1236|Gammaproteobacteria,1XXEJ@135623|Vibrionales 135623|Vibrionales J Endoribonuclease L-PSP - - - - - - - - - - - - Ribonuc_L-PSP k141_19208_3 1116375.VEJY3_07540 2.64e-54 171.0 2AWRH@1|root,31NNF@2|Bacteria,1QKD0@1224|Proteobacteria,1TIGM@1236|Gammaproteobacteria,1XZ3D@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_19208_4 1116375.VEJY3_07545 1.33e-61 189.0 298UB@1|root,2ZVYH@2|Bacteria,1NKPZ@1224|Proteobacteria,1SWFX@1236|Gammaproteobacteria,1Y2B3@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF3634) - - - - - - - - - - - - DUF3634 k141_19208_5 1116375.VEJY3_07550 7e-97 282.0 COG3120@1|root,COG3120@2|Bacteria,1RA57@1224|Proteobacteria,1S28S@1236|Gammaproteobacteria,1XWXZ@135623|Vibrionales 135623|Vibrionales D Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain matP - - ko:K09911 - - - - ko00000 - - - MatP,MatP_C k141_19208_6 1116375.VEJY3_07555 0.0 997.0 COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,1RMPC@1236|Gammaproteobacteria,1XVTZ@135623|Vibrionales 135623|Vibrionales O Belongs to the peptidase S16 family - - - ko:K04770 - - - - ko00000,ko01000,ko01002 - - - AAA_32,Lon_C k141_19208_7 223926.28806583 4.2e-125 355.0 COG0764@1|root,COG0764@2|Bacteria,1MWV8@1224|Proteobacteria,1RP6W@1236|Gammaproteobacteria,1XSI6@135623|Vibrionales 135623|Vibrionales I Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length fabA GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0008693,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019171,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 4.2.1.59,5.3.3.14 ko:K01716 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00083 R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07639 RC00831,RC01078,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FabA k141_19208_8 223926.28806584 3.51e-34 117.0 COG3130@1|root,COG3130@2|Bacteria,1N761@1224|Proteobacteria,1SCIC@1236|Gammaproteobacteria,1XYV6@135623|Vibrionales 135623|Vibrionales J During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) rmf - - ko:K03812 - - - - ko00000,ko03009 - - - RMF k141_19208_9 1116375.VEJY3_07570 9.67e-314 866.0 COG5563@1|root,COG5563@2|Bacteria,1R4Q6@1224|Proteobacteria,1T1XK@1236|Gammaproteobacteria,1XTW4@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF3466) - - - - - - - - - - - - DUF3466 k141_19208_10 1116375.VEJY3_07575 0.0 1186.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPCU@1236|Gammaproteobacteria,1XT00@135623|Vibrionales 135623|Vibrionales S COG0488 ATPase components of ABC transporters with duplicated ATPase domains uup - - ko:K15738 - - - - ko00000,ko02000 3.A.1.120.6 - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn,MMR_HSR1 k141_19208_11 223926.28806587 1.42e-50 160.0 COG0695@1|root,COG0695@2|Bacteria,1NH8Z@1224|Proteobacteria,1SGAT@1236|Gammaproteobacteria,1XYWH@135623|Vibrionales 135623|Vibrionales O COG0526 Thiol-disulfide isomerase and thioredoxins - - - - - - - - - - - - DUF836 k141_15703_2 935836.JAEL01000011_gene5218 1.63e-27 105.0 COG2050@1|root,COG2050@2|Bacteria,1VN0K@1239|Firmicutes,4HM66@91061|Bacilli,1ZHD4@1386|Bacillus 91061|Bacilli Q protein, possibly involved in aromatic compounds catabolism - - - ko:K02614 ko00360,map00360 - R09840 RC00004,RC00014 ko00000,ko00001,ko01000 - - - 4HBT k141_27521_1 42565.FP66_14065 3.87e-52 172.0 COG1023@1|root,COG1023@2|Bacteria,1QU14@1224|Proteobacteria,1T1KM@1236|Gammaproteobacteria,1XJ3X@135619|Oceanospirillales 135619|Oceanospirillales G 6-phosphogluconate dehydrogenase, C-terminal domain - - 1.1.1.343,1.1.1.44 ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 M00004,M00006 R01528,R10221 RC00001,RC00539 ko00000,ko00001,ko00002,ko01000 - - - 6PGD,NAD_binding_2 k141_35841_1 218284.CCDN010000002_gene2732 1.88e-106 317.0 COG0246@1|root,COG0246@2|Bacteria,1TPZU@1239|Firmicutes,4H9S3@91061|Bacilli,1ZD4H@1386|Bacillus 91061|Bacilli G COG0246 Mannitol-1-phosphate altronate dehydrogenases mtlD GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006059,GO:0006066,GO:0008150,GO:0008152,GO:0008926,GO:0009056,GO:0009987,GO:0016052,GO:0016491,GO:0016614,GO:0016616,GO:0019400,GO:0019405,GO:0019407,GO:0019592,GO:0019594,GO:0019751,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046164,GO:0046174,GO:0055114,GO:0071704,GO:1901575,GO:1901615,GO:1901616 1.1.1.17 ko:K00009 ko00051,map00051 - R02703 RC00085 ko00000,ko00001,ko01000 - - - Mannitol_dh,Mannitol_dh_C k141_7369_1 218284.CCDN010000002_gene2593 3.84e-106 319.0 COG0642@1|root,COG2205@2|Bacteria,1V10X@1239|Firmicutes,4H9UD@91061|Bacilli,1ZS4A@1386|Bacillus 91061|Bacilli T COG0642 Signal transduction histidine kinase yclK - - - - - - - - - - - HAMP,HATPase_c,HisKA k141_28805_1 926550.CLDAP_00740 6.1e-52 180.0 COG0248@1|root,COG0248@2|Bacteria,2G776@200795|Chloroflexi 200795|Chloroflexi FP PFAM Ppx GppA phosphatase - - 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 - R03409 RC00002 ko00000,ko00001,ko01000 - - - CHAD,HD,Ppx-GppA k141_34673_1 1294265.JCM21738_3910 1.28e-63 194.0 COG1733@1|root,COG1733@2|Bacteria,1VBI7@1239|Firmicutes,4HKBR@91061|Bacilli,1ZH23@1386|Bacillus 91061|Bacilli K transcriptional yodB GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - - - - - - - - - - HxlR k141_10884_1 218284.CCDN010000006_gene3567 7.89e-80 245.0 COG1090@1|root,COG1090@2|Bacteria,1TSEG@1239|Firmicutes,4HEV9@91061|Bacilli,1ZB7I@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF1731) - - - ko:K07071 - - - - ko00000 - - - DUF1731,Epimerase k141_26441_1 935836.JAEL01000026_gene5023 1.36e-252 735.0 COG1074@1|root,COG1074@2|Bacteria,1TQ35@1239|Firmicutes,4HA64@91061|Bacilli,1ZBG6@1386|Bacillus 91061|Bacilli L ATP-dependent helicase nuclease subunit A addA GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 3.6.4.12 ko:K16898 - - - - ko00000,ko01000,ko03400 - - - PDDEXK_1,UvrD-helicase,UvrD_C k141_16848_1 985665.HPL003_22345 8.88e-131 377.0 COG0492@1|root,COG0492@2|Bacteria,1TSQS@1239|Firmicutes,4HC5G@91061|Bacilli,26QY1@186822|Paenibacillaceae 91061|Bacilli O Pyridine nucleotide-disulfide oxidoreductase trxR - - - - - - - - - - - Pyr_redox_2 k141_31180_1 674977.VMC_02050 9.03e-148 432.0 COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,1RMPG@1236|Gammaproteobacteria,1XU5H@135623|Vibrionales 135623|Vibrionales L DNA helicase recQ - 3.6.4.12 ko:K03654 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind k141_6282_1 1131269.AQVV01000036_gene1493 8.71e-86 282.0 COG0086@1|root,COG0086@2|Bacteria 2|Bacteria K DNA-directed 5'-3' RNA polymerase activity rpoC GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 ko:K03046,ko:K13797 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 k141_33492_1 218284.CCDN010000006_gene3664 4.02e-29 112.0 2DBB1@1|root,2Z854@2|Bacteria,1TT9P@1239|Firmicutes,4HDSP@91061|Bacilli,1ZEVA@1386|Bacillus 91061|Bacilli S Domain of Unknown Function (DUF1206) - - - - - - - - - - - - DUF1206 k141_317_1 1415778.JQMM01000001_gene2175 4.02e-20 89.0 COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,1RN6U@1236|Gammaproteobacteria,1J56Y@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits - - 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_N k141_317_2 697282.Mettu_0383 3.92e-38 132.0 COG0355@1|root,COG0355@2|Bacteria,1N1NE@1224|Proteobacteria,1S9B5@1236|Gammaproteobacteria,1XFSN@135618|Methylococcales 135618|Methylococcales C ATP synthase, Delta/Epsilon chain, beta-sandwich domain - - - ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_DE_N k141_18117_1 218284.CCDN010000001_gene725 1.08e-75 235.0 COG1466@1|root,COG1466@2|Bacteria,1TRM0@1239|Firmicutes,4HBB4@91061|Bacilli,1ZBST@1386|Bacillus 91061|Bacilli L DNA polymerase III delta subunit holA - 2.7.7.7 ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta k141_8541_3 218284.CCDN010000006_gene3505 1.19e-46 152.0 COG0526@1|root,COG0526@2|Bacteria,1VEVR@1239|Firmicutes,4HNM9@91061|Bacilli,1ZIVX@1386|Bacillus 91061|Bacilli CO Thioredoxin yusE GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - - - - - - - - - - Thioredoxin k141_26443_1 935836.JAEL01000083_gene1124 3.57e-64 212.0 COG1620@1|root,COG1620@2|Bacteria,1TQNM@1239|Firmicutes,4HAF3@91061|Bacilli,1ZC0U@1386|Bacillus 91061|Bacilli C L-lactate permease - - - ko:K03303 - - - - ko00000,ko02000 2.A.14 - - Lactate_perm k141_4946_2 1279017.AQYJ01000025_gene622 6.27e-74 253.0 COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1MUKF@1224|Proteobacteria,1RMW6@1236|Gammaproteobacteria,464JA@72275|Alteromonadaceae 1236|Gammaproteobacteria S DNA internalization-related competence protein ComEC Rec2 ycaI GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02238 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - Competence,DUF4131,Lactamase_B k141_31182_1 1453501.JELR01000002_gene535 1.08e-85 264.0 COG1162@1|root,COG1162@2|Bacteria,1MUEF@1224|Proteobacteria,1RMMB@1236|Gammaproteobacteria,465K2@72275|Alteromonadaceae 1236|Gammaproteobacteria S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit rsgA2 - 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 - R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 - - - RsgA_GTPase k141_1381_1 1042377.AFPJ01000014_gene1649 9.92e-55 185.0 COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,1RNM1@1236|Gammaproteobacteria,463YZ@72275|Alteromonadaceae 1236|Gammaproteobacteria E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides pepA GO:0001073,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004177,GO:0005488,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006351,GO:0006355,GO:0006508,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009056,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016787,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019538,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042150,GO:0043170,GO:0043171,GO:0043244,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140096,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1903506,GO:2000112,GO:2001141 3.4.11.1 ko:K01255 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - Peptidase_M17,Peptidase_M17_N k141_12151_1 1294265.JCM21738_4847 1.57e-65 201.0 COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,4HA31@91061|Bacilli,1ZBNF@1386|Bacillus 91061|Bacilli O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain yyxA - 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Trypsin_2 k141_37025_2 218284.CCDN010000001_gene1023 4.17e-33 124.0 COG3570@1|root,COG3570@2|Bacteria,1V5G9@1239|Firmicutes,4HH9E@91061|Bacilli,1ZFTN@1386|Bacillus 91061|Bacilli V Aminoglycoside/hydroxyurea antibiotic resistance kinase - - 2.7.1.72 ko:K04343 - M00766 R02225 RC00002,RC00078 br01600,ko00000,ko00002,ko01000,ko01504 - - - APH_6_hur k141_26444_1 218284.CCDN010000001_gene779 2.59e-60 196.0 COG0821@1|root,COG0821@2|Bacteria,1TPFR@1239|Firmicutes,4H9S1@91061|Bacilli,1ZCV1@1386|Bacillus 91061|Bacilli I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate ispG GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R08689,R10859 RC01486 ko00000,ko00001,ko00002,ko01000 - - - GcpE k141_22795_1 1219076.N646_1542 5.12e-140 414.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XSRH@135623|Vibrionales 135623|Vibrionales T signal transduction protein containing a membrane domain, an EAL and a GGDEF domain VV2690 - 3.1.4.52 ko:K20965 ko05111,map05111 - - - ko00000,ko00001,ko01000 - - - EAL,GGDEF,PAS_4,PAS_8,PAS_9 k141_22795_2 223926.28807445 1.36e-244 671.0 COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,1RP6X@1236|Gammaproteobacteria,1XTKH@135623|Vibrionales 135623|Vibrionales O COG0826 Collagenase and related proteases yhbU - - ko:K08303 ko05120,map05120 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_U32 k141_22795_3 223926.28807446 5.11e-208 575.0 COG0826@1|root,COG0826@2|Bacteria,1MWFW@1224|Proteobacteria,1RMWM@1236|Gammaproteobacteria,1XT2K@135623|Vibrionales 135623|Vibrionales O COG0826 Collagenase and related proteases yhbV - - - - - - - - - - - Peptidase_U32 k141_22795_4 1116375.VEJY3_12660 5.73e-275 758.0 COG0534@1|root,COG0534@2|Bacteria,1R4H5@1224|Proteobacteria,1RS0B@1236|Gammaproteobacteria,1XTRQ@135623|Vibrionales 135623|Vibrionales V Na driven multidrug efflux pump vmrA - - - - - - - - - - - MatE k141_22795_5 1116375.VEJY3_12665 7.32e-40 140.0 COG4785@1|root,COG4785@2|Bacteria,1N02Y@1224|Proteobacteria,1RP8P@1236|Gammaproteobacteria,1XT95@135623|Vibrionales 135623|Vibrionales M May be involved in cell division nlpI - - ko:K05803 - - - - ko00000 - - - TPR_8 k141_31183_1 218284.CCDN010000005_gene3464 1.13e-97 296.0 COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,4HAAI@91061|Bacilli,1ZBC5@1386|Bacillus 91061|Bacilli S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family - - - ko:K03308 - - - - ko00000 2.A.22.4,2.A.22.5 - - SNF k141_26445_1 1231057.AMGD01000056_gene189 8.61e-101 303.0 COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,4HAE3@91061|Bacilli,26EHW@186818|Planococcaceae 91061|Bacilli E Receptor family ligand binding region braC - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 k141_1382_1 314285.KT71_17436 5.5e-32 112.0 COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,1J6R5@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria K 'Cold-shock' DNA-binding domain cspE - - ko:K03704 - - - - ko00000,ko03000 - - - CSD k141_12152_1 1121938.AUDY01000008_gene935 3.04e-13 68.9 COG0477@1|root,COG2814@2|Bacteria,1TQXU@1239|Firmicutes,4HAYB@91061|Bacilli 91061|Bacilli EGP Transporter - - - ko:K19577 - - - - ko00000,ko02000 2.A.1.2.65 - - MFS_1,Sugar_tr k141_12152_2 1385510.N781_04625 1.22e-45 155.0 COG1414@1|root,COG1414@2|Bacteria,1V23J@1239|Firmicutes,4HFYV@91061|Bacilli 91061|Bacilli K Bacterial transcriptional regulator - - - - - - - - - - - - HTH_IclR,IclR k141_7383_1 1279017.AQYJ01000027_gene1572 1.55e-254 708.0 COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,1RMPS@1236|Gammaproteobacteria,4654W@72275|Alteromonadaceae 1236|Gammaproteobacteria G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration nnrD GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 - - - - ko00000,ko01000 - - - Carb_kinase,YjeF_N k141_1390_1 1453501.JELR01000006_gene1 0.0 898.0 COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,1RR2W@1236|Gammaproteobacteria,465RW@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG3666 Transposase and inactivated derivatives - - - - - - - - - - - - DDE_Tnp_1_6,DUF772 k141_26476_2 218284.CCDN010000005_gene3223 7.29e-103 313.0 COG2206@1|root,COG2206@2|Bacteria,1UZN2@1239|Firmicutes,4HIY3@91061|Bacilli,1ZS2G@1386|Bacillus 91061|Bacilli T HD domain - - - - - - - - - - - - HD,HD_5 k141_22821_1 218284.CCDN010000007_gene3921 2.28e-124 360.0 COG1028@1|root,COG1028@2|Bacteria,1TVGW@1239|Firmicutes,4HAP9@91061|Bacilli,1ZQ6A@1386|Bacillus 91061|Bacilli IQ Enoyl-(Acyl carrier protein) reductase - - - - - - - - - - - - adh_short k141_18138_1 218284.CCDN010000006_gene3681 8.88e-76 231.0 COG2884@1|root,COG2884@2|Bacteria,1TP58@1239|Firmicutes,4H9Z2@91061|Bacilli,1ZCAE@1386|Bacillus 91061|Bacilli D cell division ATP-binding protein FtsE ftsE GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0008356,GO:0009966,GO:0009987,GO:0010646,GO:0016020,GO:0016043,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0032506,GO:0042173,GO:0043937,GO:0043938,GO:0044085,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0051301,GO:0065007,GO:0070297,GO:0071840,GO:0071944,GO:0090529,GO:1902531 - ko:K09812 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - ABC_tran k141_34702_1 1453501.JELR01000002_gene340 1.65e-201 566.0 COG3182@1|root,COG3182@2|Bacteria,1MW2S@1224|Proteobacteria,1RQYY@1236|Gammaproteobacteria,46CKU@72275|Alteromonadaceae 1236|Gammaproteobacteria S PepSY-associated TM region - - - - - - - - - - - - PepSY,PepSY_TM k141_34702_2 1453501.JELR01000002_gene339 6.16e-21 90.9 COG1629@1|root,COG4771@2|Bacteria,1MUPZ@1224|Proteobacteria,1RMMP@1236|Gammaproteobacteria,464D4@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport acr - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_8558_1 1453501.JELR01000001_gene2313 9.31e-08 52.4 COG0007@1|root,COG1648@1|root,COG0007@2|Bacteria,COG1648@2|Bacteria,1MUI0@1224|Proteobacteria,1RM9V@1236|Gammaproteobacteria,4645Q@72275|Alteromonadaceae 1236|Gammaproteobacteria H Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme cysG - 1.3.1.76,2.1.1.107,4.99.1.4 ko:K02302,ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02864,R03194,R03947 RC00003,RC00871,RC01012,RC01034 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_3999 CysG_dimeriser,NAD_binding_7,Sirohm_synth_M,TP_methylase k141_35864_1 218284.CCDN010000003_gene2964 9.7e-66 200.0 COG3870@1|root,COG3870@2|Bacteria,1V6NI@1239|Firmicutes,4HIHA@91061|Bacilli,1ZHEA@1386|Bacillus 91061|Bacilli S protein conserved in bacteria yaaQ - - - - - - - - - - - CdAMP_rec k141_35864_2 218284.CCDN010000003_gene2965 2.6e-77 233.0 COG1728@1|root,COG1728@2|Bacteria,1VF6M@1239|Firmicutes,4HP8D@91061|Bacilli,1ZFYU@1386|Bacillus 91061|Bacilli S protein conserved in bacteria yaaR - - ko:K09770 - - - - ko00000 - - - DUF327 k141_35864_3 218284.CCDN010000003_gene2966 3.77e-10 59.3 COG0470@1|root,COG0470@2|Bacteria,1TRVS@1239|Firmicutes,4HA3T@91061|Bacilli,1ZBDA@1386|Bacillus 91061|Bacilli L DNA polymerase III holB GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576 2.7.7.7 ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNApol3-delta_C k141_16872_1 1042377.AFPJ01000025_gene616 1.46e-111 324.0 COG1225@1|root,COG1225@2|Bacteria,1RD2X@1224|Proteobacteria,1S3TJ@1236|Gammaproteobacteria,4673G@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG0526 Thiol-disulfide isomerase and thioredoxins - - - - - - - - - - - - AhpC-TSA k141_16872_2 1122194.AUHU01000005_gene932 1.69e-67 226.0 COG4232@1|root,COG4233@1|root,COG4232@2|Bacteria,COG4233@2|Bacteria,1MU8W@1224|Proteobacteria,1RPF7@1236|Gammaproteobacteria,46550@72275|Alteromonadaceae 1236|Gammaproteobacteria CO Thiol disulfide interchange protein - - 1.8.1.8 ko:K04084 - - - - ko00000,ko01000,ko03110 5.A.1.1 - - DsbC,DsbD,Thioredoxin_7 k141_19235_1 1453501.JELR01000001_gene2440 2.32e-247 698.0 COG0417@1|root,COG0417@2|Bacteria,1MVY9@1224|Proteobacteria,1RMQ1@1236|Gammaproteobacteria,4640I@72275|Alteromonadaceae 1236|Gammaproteobacteria L DNA polymerase polB GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0018130,GO:0019438,GO:0031668,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0045004,GO:0045005,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02336 - - - - ko00000,ko01000,ko03400 - - - DNA_pol_B,DNA_pol_B_exo1 k141_28824_1 756499.Desde_0379 1.78e-11 65.1 COG1434@1|root,COG1434@2|Bacteria,1VA42@1239|Firmicutes,24HKK@186801|Clostridia,2662U@186807|Peptococcaceae 186801|Clostridia S PFAM DUF218 domain - - - - - - - - - - - - DUF218 k141_28824_2 1034347.CAHJ01000066_gene2878 1.02e-36 129.0 2A0MF@1|root,30NRR@2|Bacteria,1UATI@1239|Firmicutes,4IM6B@91061|Bacilli,1ZJAS@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_28824_3 218284.CCDN010000002_gene2693 1.17e-82 248.0 COG0703@1|root,COG0703@2|Bacteria,1V25K@1239|Firmicutes,4HFS0@91061|Bacilli,1ZFAN@1386|Bacillus 91061|Bacilli E AAA domain - - - - - - - - - - - - AAA_18 k141_6305_1 218284.CCDN010000002_gene2252 7.12e-135 397.0 COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,4HBUS@91061|Bacilli,1ZB01@1386|Bacillus 91061|Bacilli EH Belongs to the TPP enzyme family ydaP - 1.2.3.3 ko:K00158 ko00620,ko01100,map00620,map01100 - R00207 RC02745 ko00000,ko00001,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N k141_7384_1 1123008.KB905705_gene975 2.02e-10 65.5 2DSTI@1|root,33HD4@2|Bacteria,4NYHV@976|Bacteroidetes,2FZJE@200643|Bacteroidia 976|Bacteroidetes - - - - - - - - - - - - - - - k141_13350_2 1121923.GPUN_2029 3.91e-49 159.0 COG3296@1|root,COG3296@2|Bacteria,1N31K@1224|Proteobacteria,1T0FI@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF4870) - - - ko:K09940 - - - - ko00000 - - - DUF4870,SHOCT k141_26478_2 218284.CCDN010000001_gene1850 2.88e-17 79.0 COG1013@1|root,COG1013@2|Bacteria,1TQJ2@1239|Firmicutes,4HAA4@91061|Bacilli,1ZCCX@1386|Bacillus 91061|Bacilli C COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit korB - 1.2.7.11,1.2.7.3 ko:K00175 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - PFO_beta_C,TPP_enzyme_C k141_18139_1 1328313.DS2_13544 5.77e-57 197.0 COG2274@1|root,COG2274@2|Bacteria,1R2T0@1224|Proteobacteria,1SBE1@1236|Gammaproteobacteria,464I6@72275|Alteromonadaceae 1236|Gammaproteobacteria V COG2274 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain cvaB - - ko:K06147,ko:K13409 ko02010,ko04626,map02010,map04626 M00339 - - ko00000,ko00001,ko00002,ko02000,ko02044 3.A.1.106,3.A.1.109,3.A.1.110,3.A.1.21 - - ABC_membrane,ABC_tran,Peptidase_C39,cNMP_binding k141_33502_1 1453501.JELR01000002_gene486 1.09e-136 412.0 COG1629@1|root,COG4771@2|Bacteria,1MUWN@1224|Proteobacteria,1S005@1236|Gammaproteobacteria,46A62@72275|Alteromonadaceae 1236|Gammaproteobacteria P Outer membrane protein beta-barrel family - - - - - - - - - - - - Plug,TonB_dep_Rec k141_37044_1 1453501.JELR01000002_gene945 2.89e-208 598.0 COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,1RN3Z@1236|Gammaproteobacteria,465HK@72275|Alteromonadaceae 1236|Gammaproteobacteria U COG4796 Type II secretory pathway, component HofQ pilQ GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0015976,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 - ko:K02507,ko:K02666 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - AMIN,STN,Secretin,Secretin_N k141_37044_2 1279017.AQYJ01000027_gene1583 6.12e-92 272.0 COG0703@1|root,COG0703@2|Bacteria,1MUFJ@1224|Proteobacteria,1RPF6@1236|Gammaproteobacteria,467A5@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate aroK GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - SKI k141_19236_1 218284.CCDN010000001_gene810 6.4e-80 237.0 COG1733@1|root,COG1733@2|Bacteria,1V43K@1239|Firmicutes,4HH01@91061|Bacilli,1ZGIV@1386|Bacillus 91061|Bacilli K Transcriptional regulator ytcD - - - - - - - - - - - HxlR k141_3862_1 218284.CCDN010000001_gene1383 6.73e-69 215.0 COG0345@1|root,COG0345@2|Bacteria,1TP1E@1239|Firmicutes,4H9RV@91061|Bacilli,1ZCWZ@1386|Bacillus 91061|Bacilli E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline proC - 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU18480 F420_oxidored,P5CR_dimer k141_13351_1 1122194.AUHU01000004_gene1446 4.67e-107 322.0 COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,1RPZC@1236|Gammaproteobacteria,465AN@72275|Alteromonadaceae 1236|Gammaproteobacteria J exonuclease of the beta-lactamase fold involved in RNA processing - - - ko:K07576 - - - - ko00000 - - - Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL k141_10909_1 1042377.AFPJ01000042_gene1029 1.45e-53 181.0 COG1940@1|root,COG1940@2|Bacteria,1MU94@1224|Proteobacteria,1RQ3P@1236|Gammaproteobacteria,466G9@72275|Alteromonadaceae 1236|Gammaproteobacteria GK ROK family bglK - 2.7.1.2,2.7.1.4,2.7.1.85 ko:K00845,ko:K00847,ko:K18673 ko00010,ko00051,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00051,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R00760,R00867,R01600,R01786,R03920 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - ROK k141_8560_1 1294265.JCM21738_3448 1.55e-64 198.0 COG0009@1|root,COG0009@2|Bacteria,1TP1I@1239|Firmicutes,4HA7W@91061|Bacilli,1ZB2V@1386|Bacillus 91061|Bacilli J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine ywlC GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87 ko:K07566 - - R10463 RC00745 ko00000,ko01000,ko03009,ko03016 - - - SUA5,Sua5_yciO_yrdC k141_26480_1 1294265.JCM21738_3699 4.06e-97 283.0 COG0649@1|root,COG0649@2|Bacteria,1TQAR@1239|Firmicutes,4HA4Y@91061|Bacilli,1ZBPG@1386|Bacillus 91061|Bacilli C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoD GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 ko:K00333 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_49kDa k141_26480_2 1294265.JCM21738_3698 4.77e-54 179.0 COG0852@1|root,COG0852@2|Bacteria,1UFNI@1239|Firmicutes,4HDV1@91061|Bacilli,1ZB7U@1386|Bacillus 91061|Bacilli C COG0852 NADH ubiquinone oxidoreductase 27 kD subunit nuoC - 1.6.5.3 ko:K00332 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_30kDa k141_518_2 1295642.H839_08149 3.89e-29 116.0 COG3935@1|root,COG3935@2|Bacteria,1VCAM@1239|Firmicutes,4HKS4@91061|Bacilli 91061|Bacilli L Replication initiation and membrane attachment - - - - - - - - - - - - DnaB_2 k141_11114_1 218284.CCDN010000002_gene2921 1.88e-100 298.0 COG2137@1|root,COG2137@2|Bacteria,1V72V@1239|Firmicutes,4HJ7R@91061|Bacilli,1ZC8N@1386|Bacillus 91061|Bacilli S Modulates RecA activity recX - - ko:K03565 - - - - ko00000,ko03400 - - - RecX k141_20557_1 1408254.T458_18835 2.72e-41 150.0 COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,4HAXJ@91061|Bacilli,2750S@186822|Paenibacillaceae 91061|Bacilli L Transposase, Mutator family - - - - - - - - - - - - Transposase_mut k141_18299_1 1453501.JELR01000002_gene763 1.57e-34 130.0 COG0834@1|root,COG4623@1|root,COG0834@2|Bacteria,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,1RM8W@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella - GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - ko:K18691 - - - - ko00000,ko01000,ko01011 - - - SBP_bac_3,SLT k141_18299_2 1453501.JELR01000002_gene762 1.83e-73 222.0 COG0251@1|root,COG0251@2|Bacteria,1RH61@1224|Proteobacteria,1S86U@1236|Gammaproteobacteria,46CF1@72275|Alteromonadaceae 1236|Gammaproteobacteria J Endoribonuclease L-PSP - - - - - - - - - - - - Ribonuc_L-PSP k141_12417_2 218284.CCDN010000001_gene1165 1.02e-77 244.0 COG2317@1|root,COG2317@2|Bacteria,1TPS6@1239|Firmicutes,4HAPE@91061|Bacilli,1ZB3X@1386|Bacillus 91061|Bacilli E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues ypwA GO:0003674,GO:0003824,GO:0004180,GO:0004181,GO:0005488,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0016787,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.17.19 ko:K01299 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M32 k141_30019_1 663321.REG_0605 2.76e-11 68.2 COG3144@1|root,COG3144@2|Bacteria,1N86W@1224|Proteobacteria,1SER0@1236|Gammaproteobacteria,283I7@191675|unclassified Enterobacteriaceae 1236|Gammaproteobacteria N Flagellar hook-length control protein FliK lafE - - ko:K02414 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_hook k141_30019_3 1545915.JROG01000004_gene1837 3.13e-11 68.9 COG1191@1|root,COG1191@2|Bacteria,1MWEU@1224|Proteobacteria,2U7VQ@28211|Alphaproteobacteria,2K0H4@204457|Sphingomonadales 204457|Sphingomonadales K Belongs to the sigma-70 factor family fliA - - ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 - - - ko00000,ko00001,ko02035,ko03021 - - - Sigma70_r2,Sigma70_r3,Sigma70_r4 k141_30019_4 1304872.JAGC01000003_gene3775 6.75e-55 186.0 COG1291@1|root,COG1291@2|Bacteria,1MXK3@1224|Proteobacteria,42NU8@68525|delta/epsilon subdivisions,2WM5F@28221|Deltaproteobacteria,2MA6U@213115|Desulfovibrionales 28221|Deltaproteobacteria N TIGRFAM flagellar motor stator protein MotA - - - ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - MotA_ExbB k141_30019_5 1517681.HW45_22610 5.84e-33 125.0 COG1360@1|root,COG1360@2|Bacteria,1MW1Y@1224|Proteobacteria,1RPQ9@1236|Gammaproteobacteria,1XV9X@135623|Vibrionales 135623|Vibrionales N Membrane MotB of proton-channel complex MotA/MotB - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02557 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - MotB_plug,OmpA k141_26754_1 441769.ABFU01000018_gene3558 3.24e-51 179.0 COG0577@1|root,COG0577@2|Bacteria,1TPSE@1239|Firmicutes,4HCAX@91061|Bacilli,1ZBS7@1386|Bacillus 91061|Bacilli V ABC transporter (permease) YclI yclI GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD k141_21804_2 218284.CCDN010000001_gene59 1.37e-248 684.0 COG0505@1|root,COG0505@2|Bacteria,1TQ8N@1239|Firmicutes,4H9Z0@91061|Bacilli,1ZB7G@1386|Bacillus 91061|Bacilli F Carbamoyl-phosphate synthetase glutamine chain carA GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU15510 CPSase_sm_chain,GATase k141_4053_1 314292.VAS14_12169 4e-94 283.0 2BQ6V@1|root,32J1E@2|Bacteria,1PCBB@1224|Proteobacteria,1TJ2F@1236|Gammaproteobacteria,1Y0CX@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_4053_2 1116375.VEJY3_08335 9.41e-14 69.3 COG0730@1|root,COG0730@2|Bacteria,1RAG9@1224|Proteobacteria,1S2RX@1236|Gammaproteobacteria,1XWQG@135623|Vibrionales 135623|Vibrionales S membrane transporter protein - - - - - - - - - - - - TauE k141_13607_1 349521.HCH_06669 1.66e-23 96.7 COG1846@1|root,COG1846@2|Bacteria,1RFUJ@1224|Proteobacteria,1S8JQ@1236|Gammaproteobacteria,1XKUY@135619|Oceanospirillales 135619|Oceanospirillales K helix_turn_helix multiple antibiotic resistance protein - - - - - - - - - - - - MarR,MarR_2 k141_13607_2 1040986.ATYO01000002_gene4050 1.68e-26 107.0 COG0665@1|root,COG0665@2|Bacteria,1Q38Q@1224|Proteobacteria,2TTMM@28211|Alphaproteobacteria,43JYD@69277|Phyllobacteriaceae 28211|Alphaproteobacteria E Thi4 family - - - - - - - - - - - - DAO k141_9947_2 935836.JAEL01000053_gene4888 1.57e-29 105.0 COG4895@1|root,COG4895@2|Bacteria,1VEG3@1239|Firmicutes,4HNJA@91061|Bacilli,1ZIX5@1386|Bacillus 91061|Bacilli S Uncharacterized conserved protein (DUF2196) ywbE - - - - - - - - - - - DUF2196 k141_9947_3 1423321.AS29_08915 7.62e-33 115.0 COG0166@1|root,COG0166@2|Bacteria,1VFQ2@1239|Firmicutes,4HNRS@91061|Bacilli,1ZIWJ@1386|Bacillus 91061|Bacilli G Helix-turn-helix domain yoeD - - - - - - - - - - - HTH_17 k141_5155_2 674977.VMC_05750 0.0 1167.0 COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,1RN7S@1236|Gammaproteobacteria,1XUBV@135623|Vibrionales 135623|Vibrionales O COG0826 Collagenase and related proteases - - - ko:K08303 ko05120,map05120 - - - ko00000,ko00001,ko01000,ko01002 - - - DUF3656,Peptidase_U32 k141_5155_3 674977.VMC_05740 5.03e-67 207.0 COG3439@1|root,COG3439@2|Bacteria,1MZ38@1224|Proteobacteria,1S60I@1236|Gammaproteobacteria,1XY3V@135623|Vibrionales 135623|Vibrionales S Domain of unknown function DUF302 - - - - - - - - - - - - DUF302 k141_5155_4 1116375.VEJY3_24111 0.0 1328.0 COG4772@1|root,COG4772@2|Bacteria,1MWDG@1224|Proteobacteria,1RQA5@1236|Gammaproteobacteria,1XUJW@135623|Vibrionales 135623|Vibrionales P Outer membrane protein beta-barrel family - - - ko:K16091 - - - - ko00000,ko02000 1.B.14.1.14 - - Plug,TonB_dep_Rec k141_5155_5 1116375.VEJY3_24106 5.21e-61 196.0 COG4594@1|root,COG4594@2|Bacteria,1R01Z@1224|Proteobacteria,1T4DX@1236|Gammaproteobacteria,1Y26N@135623|Vibrionales 135623|Vibrionales P transporter Substrate-binding - - - ko:K02016 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - Peripla_BP_2 k141_27612_1 1279017.AQYJ01000028_gene2320 7.59e-300 844.0 COG0709@1|root,COG1252@1|root,COG0709@2|Bacteria,COG1252@2|Bacteria,1MWFG@1224|Proteobacteria,1RQ5Q@1236|Gammaproteobacteria,465WT@72275|Alteromonadaceae 1236|Gammaproteobacteria CE Belongs to the selenophosphate synthase 1 family. Class I subfamily - - 2.7.9.3 ko:K01008 ko00450,ko01100,map00450,map01100 - R03595 RC00002,RC02878 ko00000,ko00001,ko01000,ko03016 - - - AIRS,AIRS_C,Pyr_redox_2 k141_27612_2 1279017.AQYJ01000028_gene2319 5.51e-229 640.0 COG1252@1|root,COG1252@2|Bacteria,1MX96@1224|Proteobacteria,1RM9I@1236|Gammaproteobacteria,464B3@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1252 NADH dehydrogenase, FAD-containing subunit ndh - 1.6.99.3 ko:K03885 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - Pyr_redox_2 k141_27612_3 1279017.AQYJ01000028_gene2318 3.16e-130 374.0 COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,1RMX5@1236|Gammaproteobacteria,4659I@72275|Alteromonadaceae 1236|Gammaproteobacteria K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form cobB GO:0002252,GO:0002376,GO:0003674,GO:0003824,GO:0006464,GO:0006476,GO:0006807,GO:0006935,GO:0006950,GO:0006952,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018205,GO:0019213,GO:0019538,GO:0033558,GO:0034979,GO:0034983,GO:0035601,GO:0036048,GO:0036049,GO:0036055,GO:0036211,GO:0040011,GO:0042221,GO:0042330,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050896,GO:0051607,GO:0051704,GO:0051707,GO:0071704,GO:0098542,GO:0098732,GO:0140096,GO:1901564 - ko:K12410 - - - - ko00000,ko01000 - - - SIR2 k141_519_1 218284.CCDN010000002_gene2495 1.11e-25 105.0 COG3064@1|root,COG3064@2|Bacteria,1VASR@1239|Firmicutes,4HH3I@91061|Bacilli,1ZFB0@1386|Bacillus 91061|Bacilli M Host cell surface-exposed lipoprotein - - - - - - - - - - - - Lipoprotein_Ltp k141_33723_1 218284.CCDN010000001_gene758 7.85e-105 308.0 COG1806@1|root,COG1806@2|Bacteria,1TPG0@1239|Firmicutes,4HB0Q@91061|Bacilli,1ZBIT@1386|Bacillus 91061|Bacilli S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation yqfL - 2.7.11.33,2.7.4.28 ko:K09773 - - - - ko00000,ko01000 - - - Kinase-PPPase k141_25401_2 218284.CCDN010000001_gene1352 2.58e-16 77.0 COG0531@1|root,COG0531@2|Bacteria,1UIWG@1239|Firmicutes,4ISUQ@91061|Bacilli,1ZS6D@1386|Bacillus 91061|Bacilli E Spore germination protein - - - - - - - - - - - - Spore_permease k141_26755_1 218284.CCDN010000005_gene3191 1.27e-90 269.0 COG2329@1|root,COG2329@2|Bacteria,1V501@1239|Firmicutes,4HHA2@91061|Bacilli,1ZGDD@1386|Bacillus 91061|Bacilli S enzyme involved in biosynthesis of extracellular polysaccharides traP GO:0005575,GO:0016020 1.14.99.57 ko:K21481 - - - - ko00000,ko01000 - - - ABM k141_19423_1 1219076.N646_1479 1.32e-158 450.0 COG1893@1|root,COG1893@2|Bacteria,1P0AW@1224|Proteobacteria,1RR49@1236|Gammaproteobacteria,1XTJR@135623|Vibrionales 135623|Vibrionales H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid panE GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008677,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 - - - ApbA,ApbA_C k141_19423_2 1136163.M565_ctg1P1851 8.95e-177 494.0 COG3248@1|root,COG3248@2|Bacteria,1MZ2A@1224|Proteobacteria,1RMH2@1236|Gammaproteobacteria,1XUJS@135623|Vibrionales 135623|Vibrionales M Nucleoside-specific channel-forming protein, Tsx ompK - - ko:K05517 - - - - ko00000,ko02000 1.B.10 - - Channel_Tsx k141_553_1 986075.CathTA2_2121 7.2e-60 191.0 COG0235@1|root,COG0235@2|Bacteria,1TS5G@1239|Firmicutes,4HG91@91061|Bacilli 91061|Bacilli G aldolase - - 4.1.2.17 ko:K01628 ko00051,ko01120,map00051,map01120 - R02262 RC00603,RC00604 ko00000,ko00001,ko01000 - - - Aldolase_II k141_15849_1 1116375.VEJY3_10820 1.93e-99 289.0 COG3092@1|root,COG3092@2|Bacteria,1N172@1224|Proteobacteria,1S495@1236|Gammaproteobacteria,1XWYB@135623|Vibrionales 135623|Vibrionales S UPF0208 membrane protein - - - ko:K09899 - - - - ko00000 - - - DUF412 k141_15849_2 1116375.VEJY3_10825 4.54e-283 774.0 COG0282@1|root,COG0282@2|Bacteria,1MW61@1224|Proteobacteria,1RMKB@1236|Gammaproteobacteria,1XSVG@135623|Vibrionales 135623|Vibrionales F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction ackA1 GO:0003674,GO:0003824,GO:0006091,GO:0006113,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008776,GO:0009987,GO:0015980,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0044237,GO:0055114 2.7.2.1 ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00315,R01353 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - Acetate_kinase k141_15849_3 223926.28807076 0.0 1355.0 COG0280@1|root,COG0857@1|root,COG0280@2|Bacteria,COG0857@2|Bacteria,1QTS5@1224|Proteobacteria,1RMJS@1236|Gammaproteobacteria,1XT1N@135623|Vibrionales 135623|Vibrionales C belongs to the CobB CobQ family pta GO:0003674,GO:0003824,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0008959,GO:0009987,GO:0015980,GO:0016407,GO:0016740,GO:0016746,GO:0016747,GO:0044237,GO:0055114 2.3.1.8 ko:K13788 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00230,R00921 RC00004,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000 - - - AAA_26,DRTGG,PTA_PTB k141_15849_4 1116375.VEJY3_10835 7.31e-261 720.0 COG3174@1|root,COG3174@2|Bacteria,1NDBI@1224|Proteobacteria,1RRGY@1236|Gammaproteobacteria,1XUC6@135623|Vibrionales 135623|Vibrionales S Domain of unknown function (DUF4010) - - - - - - - - - - - - DUF4010,MgtC k141_15849_5 1116375.VEJY3_10840 3.28e-230 633.0 COG0435@1|root,COG0435@2|Bacteria,1MV50@1224|Proteobacteria,1RMTI@1236|Gammaproteobacteria,1XSAM@135623|Vibrionales 135623|Vibrionales O Glutathione S-transferase - - 1.8.5.7 ko:K07393 - - - - ko00000,ko01000 - - - GST_C_2,GST_N_2 k141_15849_6 1116375.VEJY3_10845 2.8e-229 632.0 COG4608@1|root,COG4608@2|Bacteria,1NU4K@1224|Proteobacteria,1SKPD@1236|Gammaproteobacteria,1XUJP@135623|Vibrionales 135623|Vibrionales P Belongs to the ABC transporter superfamily oppF - - ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY k141_15849_7 1116375.VEJY3_10850 2.93e-232 639.0 COG0444@1|root,COG0444@2|Bacteria,1R4KB@1224|Proteobacteria,1SMBI@1236|Gammaproteobacteria,1XSWQ@135623|Vibrionales 135623|Vibrionales P Belongs to the ABC transporter superfamily oppD - - ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY k141_15849_8 223926.28807082 2.6e-203 564.0 COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,1RND6@1236|Gammaproteobacteria,1XT8X@135623|Vibrionales 135623|Vibrionales P COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components oppC - - ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - BPD_transp_1,OppC_N k141_15849_9 1116375.VEJY3_10860 1.64e-209 580.0 COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,1RNJ1@1236|Gammaproteobacteria,1XUSF@135623|Vibrionales 135623|Vibrionales P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components oppB - - ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - BPD_transp_1 k141_15849_10 1116375.VEJY3_10865 1.03e-215 606.0 COG4166@1|root,COG4166@2|Bacteria,1P91R@1224|Proteobacteria,1RN57@1236|Gammaproteobacteria,1XTB9@135623|Vibrionales 135623|Vibrionales E COG4166 ABC-type oligopeptide transport system, periplasmic component oppA - - ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 k141_5194_2 1453501.JELR01000001_gene2028 5.08e-06 47.8 COG3047@1|root,COG3047@2|Bacteria 2|Bacteria - - ompW - - ko:K07275 - - - - ko00000 - - - OmpW k141_19444_1 1384049.CD29_15045 3.13e-104 314.0 COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,4H9X4@91061|Bacilli,3IX4M@400634|Lysinibacillus 91061|Bacilli J Belongs to the class-II aminoacyl-tRNA synthetase family - - - - - - - - - - - - tRNA-synt_2,tRNA_anti-codon k141_25436_1 935836.JAEL01000070_gene3989 4.62e-105 314.0 COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,4HA6H@91061|Bacilli,1ZB1B@1386|Bacillus 91061|Bacilli E Cysteine desulfurase iscS - 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - - Aminotran_5 k141_34877_1 218284.CCDN010000001_gene384 3.79e-93 290.0 COG0476@1|root,COG0476@2|Bacteria,1UZJC@1239|Firmicutes,4HB2K@91061|Bacilli,1ZBN2@1386|Bacillus 91061|Bacilli H bacteriocin maturation protein - - - - - - - - - - - - - k141_20580_1 1294265.JCM21738_2506 4.7e-46 157.0 COG1404@1|root,COG1404@2|Bacteria,1TSRI@1239|Firmicutes,4HBFB@91061|Bacilli,1ZCQD@1386|Bacillus 91061|Bacilli O Subtilase family - - 3.4.21.62 ko:K01342 ko02024,map02024 - - - ko00000,ko00001,ko01000,ko01002,ko03110 - - - Peptidase_S8 k141_12456_1 1408303.JNJJ01000046_gene964 5.21e-234 652.0 COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,4H9NW@91061|Bacilli,1ZCU1@1386|Bacillus 91061|Bacilli L RNA-directed DNA polymerase (reverse transcriptase) - - 2.7.7.49 ko:K00986 - - - - ko00000,ko01000 - - - GIIM,RVT_1 k141_4065_1 1499680.CCFE01000018_gene1399 5.55e-32 117.0 COG0127@1|root,COG0127@2|Bacteria,1V6RN@1239|Firmicutes,4HCP6@91061|Bacilli,1ZFJM@1386|Bacillus 91061|Bacilli F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions rdgB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 ko:K02428 ko00230,map00230 - R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000 - - - Ham1p_like k141_35988_1 1042377.AFPJ01000055_gene989 2.14e-105 305.0 COG0098@1|root,COG0098@2|Bacteria,1MUS4@1224|Proteobacteria,1RNEV@1236|Gammaproteobacteria,464RY@72275|Alteromonadaceae 1236|Gammaproteobacteria J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body rpsE GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990145,GO:1990904 - ko:K02988 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S5,Ribosomal_S5_C k141_18322_2 997296.PB1_08057 7.46e-64 206.0 COG0009@1|root,COG0009@2|Bacteria,1TP1I@1239|Firmicutes,4HA7W@91061|Bacilli,1ZB2V@1386|Bacillus 91061|Bacilli J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine ywlC GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87 ko:K07566 - - R10463 RC00745 ko00000,ko01000,ko03009,ko03016 - - - SUA5,Sua5_yciO_yrdC k141_11142_1 1219076.N646_2289 6.5e-71 219.0 COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,1RPRN@1236|Gammaproteobacteria,1XTQ1@135623|Vibrionales 135623|Vibrionales U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides tatC - - ko:K03118 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - TatC k141_11142_2 1116375.VEJY3_00465 1.08e-243 674.0 COG3263@1|root,COG3263@2|Bacteria,1MVKV@1224|Proteobacteria,1T2D1@1236|Gammaproteobacteria 1236|Gammaproteobacteria P COG0025 NhaP-type Na H and K H antiporters - - - ko:K11105 - - - - ko00000,ko02000 2.A.36.6 - - Na_H_Exchanger k141_11142_3 1116375.VEJY3_00470 6.35e-107 312.0 COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,1SPRE@1236|Gammaproteobacteria,1XUSU@135623|Vibrionales 135623|Vibrionales L COG0084 Mg-dependent DNase tatD - - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase k141_34878_1 1453501.JELR01000002_gene1300 8.23e-69 219.0 COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,1RN5Z@1236|Gammaproteobacteria,46525@72275|Alteromonadaceae 1236|Gammaproteobacteria S permease VP2476 - - - - - - - - - - - AI-2E_transport k141_12457_1 218284.CCDN010000001_gene1732 1.6e-53 175.0 COG1284@1|root,COG1284@2|Bacteria,1TQTP@1239|Firmicutes,4HBV2@91061|Bacilli,1ZCF3@1386|Bacillus 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2179) - - - - - - - - - - - - DUF2179,YitT_membrane k141_554_1 218284.CCDN010000001_gene1749 4.19e-139 425.0 COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1TPYV@1239|Firmicutes,4HBER@91061|Bacilli,1ZBGN@1386|Bacillus 91061|Bacilli E Methionine synthase metH - 2.1.1.13 ko:K00548 ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230 M00017 R00946,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans k141_28936_1 223926.28807829 4.76e-122 366.0 COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,1RM89@1236|Gammaproteobacteria,1XTP3@135623|Vibrionales 135623|Vibrionales L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex mutL GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K03572 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - DNA_mis_repair,HATPase_c_3,MutL_C k141_28936_2 223926.28807830 0.0 1009.0 COG0860@1|root,COG1388@1|root,COG0860@2|Bacteria,COG1388@2|Bacteria,1MUQK@1224|Proteobacteria,1RMP1@1236|Gammaproteobacteria,1XU2J@135623|Vibrionales 135623|Vibrionales M N-acetylmuramoyl-L-alanine amidase amiB - 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - AMIN,Amidase_3,LysM k141_28936_3 1219076.N646_1911 9.12e-109 313.0 COG0802@1|root,COG0802@2|Bacteria,1RGYU@1224|Proteobacteria,1S6IB@1236|Gammaproteobacteria,1XUDS@135623|Vibrionales 135623|Vibrionales S ATPase or kinase yjeE - - ko:K06925 - - - - ko00000,ko03016 - - - TsaE k141_28936_4 1116375.VEJY3_14380 3.32e-262 719.0 COG1600@1|root,COG1600@2|Bacteria,1MV1H@1224|Proteobacteria,1RMD9@1236|Gammaproteobacteria,1XSXR@135623|Vibrionales 135623|Vibrionales C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) queG GO:0003674,GO:0003824,GO:0006091,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009055,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0022900,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 ko:K18979 - - - - ko00000,ko01000,ko03016 - - - DUF1730,Fer4_16 k141_18323_1 218284.CCDN010000008_gene4094 6.97e-107 323.0 COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,4HA1G@91061|Bacilli,1ZASC@1386|Bacillus 91061|Bacilli G COG0366 Glycosidases treC - 3.2.1.93 ko:K01226 ko00500,map00500 - R00837,R06113 RC00049 ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,DUF3459,Malt_amylase_C k141_14646_1 1453501.JELR01000005_gene1644 6.91e-70 214.0 COG2050@1|root,COG2050@2|Bacteria,1RGVP@1224|Proteobacteria,1S5WY@1236|Gammaproteobacteria,468JY@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Thioesterase superfamily menI GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0061522,GO:0071704,GO:1901576,GO:1901661,GO:1901663 3.1.2.28 ko:K19222 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R07262 RC00004,RC00174 ko00000,ko00001,ko00002,ko01000 - - - 4HBT k141_12458_1 1294265.JCM21738_3337 4.04e-100 313.0 COG0069@1|root,COG0070@1|root,COG0069@2|Bacteria,COG0070@2|Bacteria,1TQ0B@1239|Firmicutes,4HA4G@91061|Bacilli,1ZBFF@1386|Bacillus 91061|Bacilli E glutamate synthase gltA2 - 1.4.1.13,1.4.1.14 ko:K00265 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - GATase_2,GXGXG,Glu_syn_central,Glu_synthase k141_25438_1 218284.CCDN010000005_gene3299 2.01e-51 171.0 COG0564@1|root,COG0564@2|Bacteria,1TS1T@1239|Firmicutes,4HBRY@91061|Bacilli,1ZB25@1386|Bacillus 91061|Bacilli J Responsible for synthesis of pseudouridine from uracil rluD GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23,5.4.99.28,5.4.99.29 ko:K06177,ko:K06180 - - - - ko00000,ko01000,ko03009,ko03016 - - - PseudoU_synth_2 k141_11143_2 218284.CCDN010000004_gene3056 1.81e-95 280.0 2DKHE@1|root,309GB@2|Bacteria,1U50R@1239|Firmicutes,4IESM@91061|Bacilli,1ZI04@1386|Bacillus 91061|Bacilli S Intracellular proteinase inhibitor - - - - - - - - - - - - BsuPI k141_34879_1 218284.CCDN010000001_gene1909 8.57e-93 283.0 COG2201@1|root,COG2201@2|Bacteria,1TRHC@1239|Firmicutes,4HBJY@91061|Bacilli,1ZC36@1386|Bacillus 91061|Bacilli NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR cheB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.1.1.61,3.5.1.44 ko:K03412 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 - - - CheB_methylest,Response_reg k141_37208_1 218284.CCDN010000001_gene46 7.58e-94 298.0 COG1198@1|root,COG1198@2|Bacteria,1TNYB@1239|Firmicutes,4H9WW@91061|Bacilli,1ZCBY@1386|Bacillus 91061|Bacilli L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA priA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - ko:K04066 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,ResIII k141_25439_1 218284.CCDN010000006_gene3603 3e-57 192.0 COG0642@1|root,COG2205@2|Bacteria,1V10X@1239|Firmicutes,4HAU7@91061|Bacilli,1ZB6A@1386|Bacillus 91061|Bacilli T Histidine kinase - - - - - - - - - - - - HAMP,HATPase_c,HisKA k141_33745_1 1121878.AUGL01000008_gene1454 4.75e-24 106.0 COG2885@1|root,COG2885@2|Bacteria,1N6C8@1224|Proteobacteria,1SAU6@1236|Gammaproteobacteria 1236|Gammaproteobacteria M COG2885 Outer membrane protein and related peptidoglycan-associated - - - ko:K21218 ko02040,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - OmpA k141_33745_2 314292.VAS14_10054 1.57e-23 94.7 COG1677@1|root,COG1677@2|Bacteria,1N6TP@1224|Proteobacteria,1SCK1@1236|Gammaproteobacteria,1XXYT@135623|Vibrionales 135623|Vibrionales N Flagellar hook-basal body fliE - - ko:K02408 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FliE k141_33745_3 1517681.HW45_22520 1.94e-224 639.0 COG1766@1|root,COG1766@2|Bacteria,1MUQR@1224|Proteobacteria,1RN6T@1236|Gammaproteobacteria,1XTK5@135623|Vibrionales 135623|Vibrionales N The M ring may be actively involved in energy transduction - - - ko:K02409 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 - - YscJ_FliF,YscJ_FliF_C k141_33745_4 357804.Ping_3564 1.76e-79 253.0 COG1536@1|root,COG1536@2|Bacteria,1MV9X@1224|Proteobacteria,1RM9B@1236|Gammaproteobacteria,2QIC0@267894|Psychromonadaceae 1236|Gammaproteobacteria N FliG middle domain fliG - - ko:K02410 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02035 - - - FliG_C,FliG_M,FliG_N k141_33745_5 1517681.HW45_22530 2.76e-62 206.0 2DGTY@1|root,2ZX9W@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k141_26777_1 626887.J057_15150 0.0 1095.0 COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,1RN40@1236|Gammaproteobacteria,4669D@72275|Alteromonadaceae 1236|Gammaproteobacteria C Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL yagR GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016903,GO:0030151,GO:0033554,GO:0042597,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114 1.17.1.4 ko:K11177 ko00230,ko01100,ko01120,map00230,map01100,map01120 M00546 R01768,R02103 RC00143 ko00000,ko00001,ko00002,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 k141_24147_1 1042377.AFPJ01000004_gene364 6.53e-214 602.0 COG2211@1|root,COG2211@2|Bacteria,1MX4Z@1224|Proteobacteria,1RRNW@1236|Gammaproteobacteria,464IV@72275|Alteromonadaceae 1236|Gammaproteobacteria G COG0477 Permeases of the major facilitator superfamily - - - ko:K16211 - - - - ko00000,ko02000 2.A.2.6 - - MFS_1,MFS_2 k141_24147_3 1279017.AQYJ01000028_gene2283 4.83e-82 247.0 COG1376@1|root,COG1376@2|Bacteria,1Q823@1224|Proteobacteria,1S0YT@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Pfam L,D-transpeptidase catalytic domain - - - - - - - - - - - - YkuD k141_24147_5 1042377.AFPJ01000004_gene373 0.0 944.0 COG0366@1|root,COG0366@2|Bacteria,1MVKX@1224|Proteobacteria,1RMSH@1236|Gammaproteobacteria,465W2@72275|Alteromonadaceae 1236|Gammaproteobacteria G COG0366 Glycosidases aglA - 3.2.1.20 ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00028,R00801,R00802,R06087,R06088 RC00028,RC00049,RC00077 ko00000,ko00001,ko01000 - GH31 - Alpha-amylase,DUF3459,Malt_amylase_C k141_24147_6 1279017.AQYJ01000028_gene2297 0.0 1383.0 COG2909@1|root,COG2909@2|Bacteria,1MVZZ@1224|Proteobacteria,1RN29@1236|Gammaproteobacteria,46AB4@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG2909 ATP-dependent transcriptional regulator malT GO:0003674,GO:0003700,GO:0005488,GO:0005515,GO:0005975,GO:0006355,GO:0008150,GO:0008152,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030246,GO:0031323,GO:0031326,GO:0042802,GO:0044238,GO:0048031,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070492,GO:0071704,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 - ko:K03556 - - - - ko00000,ko03000 - - - AAA_16,GerE k141_24147_7 1042377.AFPJ01000004_gene375 2.98e-157 447.0 2B0GJ@1|root,31SU3@2|Bacteria,1RI4W@1224|Proteobacteria,1SA3Z@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_24147_8 1279017.AQYJ01000028_gene2299 1.69e-148 418.0 COG0491@1|root,COG0491@2|Bacteria,1MUDN@1224|Proteobacteria,1RMMG@1236|Gammaproteobacteria,464SC@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0491 Zn-dependent hydrolases, including glyoxylases ycbL GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019243,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0051596,GO:0061727,GO:0071704,GO:1901575,GO:1901615 3.1.2.6 ko:K01069 ko00620,map00620 - R01736 RC00004,RC00137 ko00000,ko00001,ko01000 - - - Lactamase_B k141_24147_9 1279017.AQYJ01000028_gene2300 1.76e-65 207.0 2E3UE@1|root,32YRS@2|Bacteria,1N75A@1224|Proteobacteria,1S9W5@1236|Gammaproteobacteria,468Q7@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF2799) - - - - - - - - - - - - DUF2799 k141_35989_1 323850.Shew_2868 3.32e-17 80.1 COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,1RPHJ@1236|Gammaproteobacteria,2QDQD@267890|Shewanellaceae 1236|Gammaproteobacteria C PFAM acyl-CoA dehydrogenase domain protein bcd - 1.3.8.1 ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 - R01175,R01178,R02661,R03172,R04751 RC00052,RC00068,RC00076,RC00120,RC00148 ko00000,ko00001,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N k141_35989_2 1453501.JELR01000001_gene1867 4.4e-50 166.0 COG0726@1|root,COG0726@2|Bacteria,1RBMV@1224|Proteobacteria,1S27I@1236|Gammaproteobacteria,467E3@72275|Alteromonadaceae 1236|Gammaproteobacteria G Polysaccharide deacetylase - - - - - - - - - - - - Polysacc_deac_1 k141_34880_1 1453501.JELR01000001_gene1906 2.06e-59 193.0 COG2885@1|root,COG2885@2|Bacteria,1R8DG@1224|Proteobacteria,1RP3K@1236|Gammaproteobacteria,466H7@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the ompA family oprF GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - ko:K03286 - - - - ko00000,ko02000 1.B.6 - - OMP_b-brl,OmpA,OprF,TSP_3 k141_20582_1 1294265.JCM21738_2215 9.06e-78 239.0 2CEA6@1|root,3054I@2|Bacteria,1TXPK@1239|Firmicutes,4I6QF@91061|Bacilli,1ZC2A@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_11144_1 218284.CCDN010000002_gene2713 3.95e-113 334.0 COG4927@1|root,COG4927@2|Bacteria,1TQGX@1239|Firmicutes,4HATV@91061|Bacilli,1ZC2P@1386|Bacillus 91061|Bacilli S Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase - - - - - - - - - - - - AAT k141_4066_1 1294265.JCM21738_2040 8.66e-54 171.0 2CEWW@1|root,32S0Q@2|Bacteria,1VAEG@1239|Firmicutes,4HGSK@91061|Bacilli,1ZCXE@1386|Bacillus 91061|Bacilli S Stage III sporulation protein spoIIIAB - - ko:K06391 - - - - ko00000 - - - Spore_III_AB k141_4066_2 666686.B1NLA3E_15515 1.75e-93 281.0 COG3854@1|root,COG3854@2|Bacteria,1TQ23@1239|Firmicutes,4HA2K@91061|Bacilli,1ZAWB@1386|Bacillus 91061|Bacilli S stage III sporulation protein AA spoIIIAA - - ko:K06390 - - - - ko00000 - - - AAA,T2SSE k141_23092_1 1273538.G159_14160 6.43e-35 126.0 COG1647@1|root,COG1647@2|Bacteria,1TT4Y@1239|Firmicutes,4HE1V@91061|Bacilli,26FVX@186818|Planococcaceae 91061|Bacilli S Serine aminopeptidase, S33 - - 3.1.1.1 ko:K03928 - - - - ko00000,ko01000 - - - Hydrolase_4 k141_14823_1 218284.CCDN010000004_gene3024 5.74e-114 348.0 COG2183@1|root,COG2183@2|Bacteria,1TPFE@1239|Firmicutes,4HAGY@91061|Bacilli,1ZC3T@1386|Bacillus 91061|Bacilli K COG2183 Transcriptional accessory protein tex - - ko:K06959 - - - - ko00000 - - - HHH_3,S1,Tex_N,Tex_YqgF k141_18585_1 1305836.AXVE01000002_gene3254 4.24e-102 322.0 COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,4HAW9@91061|Bacilli,26EAN@186818|Planococcaceae 91061|Bacilli L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate uvrA - - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran k141_9008_1 1453501.JELR01000002_gene893 2.69e-63 196.0 COG3157@1|root,COG3157@2|Bacteria,1R9GB@1224|Proteobacteria,1RYJ5@1236|Gammaproteobacteria,4689B@72275|Alteromonadaceae 1236|Gammaproteobacteria S Type VI secretion system effector, Hcp - - - ko:K11903 ko02025,ko03070,map02025,map03070 M00334 - - ko00000,ko00001,ko00002,ko02044 - - - T6SS_HCP k141_33943_1 1294265.JCM21738_3289 6.88e-77 246.0 COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,4HA9S@91061|Bacilli,1ZAZ2@1386|Bacillus 91061|Bacilli O Heat shock 70 kDa protein dnaK GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0030246,GO:0030247,GO:0044464,GO:0051704,GO:0098630,GO:0098743,GO:2001065 - ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 - - HSP70 k141_24389_1 1294265.JCM21738_2709 2.15e-159 457.0 COG1982@1|root,COG1982@2|Bacteria,1TNZ9@1239|Firmicutes,4HBGC@91061|Bacilli,1ZAR0@1386|Bacillus 91061|Bacilli E Arginine speA GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008923,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564 4.1.1.17,4.1.1.19 ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 M00133,M00134 R00566,R00670 RC00299 ko00000,ko00001,ko00002,ko01000 - - - OKR_DC_1,OKR_DC_1_C k141_12708_1 501479.ACNW01000049_gene5028 4.57e-67 205.0 COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,2U952@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Belongs to the P(II) protein family glnK - - ko:K04751,ko:K04752 ko02020,map02020 - - - ko00000,ko00001 - - - P-II k141_18586_1 218284.CCDN010000001_gene559 1.35e-162 468.0 COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HA2G@91061|Bacilli,1ZAY1@1386|Bacillus 91061|Bacilli IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II lcfA - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding,AMP-binding_C k141_20762_1 1234664.AMRO01000023_gene1732 3.99e-43 152.0 COG0789@1|root,COG0789@2|Bacteria,1UYCQ@1239|Firmicutes,4HI3I@91061|Bacilli,1WHVZ@129337|Geobacillus 91061|Bacilli K Protein of unknown function (DUF4004) yhbD - - - - - - - - - - - DUF4004 k141_22018_1 1279017.AQYJ01000029_gene3389 1.05e-229 634.0 COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,1RNDC@1236|Gammaproteobacteria,464FH@72275|Alteromonadaceae 1236|Gammaproteobacteria J Tryptophanyl-tRNA synthetase trpS - 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1b k141_24390_2 196490.AUEZ01000002_gene4146 1.14e-09 58.2 COG3224@1|root,COG3224@2|Bacteria,1N2DP@1224|Proteobacteria,2UBSR@28211|Alphaproteobacteria,3JZK5@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S EthD domain - - - - - - - - - - - - EthD k141_13909_1 1348635.BBJY01000020_gene2767 1.87e-78 244.0 COG0814@1|root,COG0814@2|Bacteria,1MWGI@1224|Proteobacteria,1RMME@1236|Gammaproteobacteria,1XTGR@135623|Vibrionales 135623|Vibrionales U COG0814 Amino acid permeases mtr - - ko:K03835 - - - - ko00000,ko02000 2.A.42.1.2 - - Trp_Tyr_perm k141_13909_2 1348635.BBJY01000020_gene2766 0.0 914.0 COG3033@1|root,COG3033@2|Bacteria,1NG5U@1224|Proteobacteria,1RS6E@1236|Gammaproteobacteria,1XSXT@135623|Vibrionales 135623|Vibrionales H Belongs to the beta-eliminating lyase family tnaA GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009034,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016829,GO:0016830,GO:0019439,GO:0019752,GO:0034641,GO:0042402,GO:0042430,GO:0042436,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 4.1.99.1 ko:K01667 ko00380,map00380 - R00673 RC00209,RC00355 ko00000,ko00001,ko01000 - - - Beta_elim_lyase k141_13909_3 672.VV93_v1c41480 5.55e-156 451.0 28IW1@1|root,2Z8UB@2|Bacteria,1N1QM@1224|Proteobacteria,1RR0J@1236|Gammaproteobacteria,1XSR0@135623|Vibrionales 135623|Vibrionales S F plasmid transfer operon, TraF, protein - - - - - - - - - - - - TraF_2 k141_13909_4 1116375.VEJY3_00815 2.58e-86 255.0 COG3223@1|root,COG3223@2|Bacteria,1N0MS@1224|Proteobacteria,1T0QS@1236|Gammaproteobacteria,1XWZQ@135623|Vibrionales 135623|Vibrionales S Phosphate-starvation-inducible E - - - ko:K13256 - - - - ko00000 - - - PsiE k141_13909_5 1116375.VEJY3_00810 1.1e-137 393.0 COG4608@1|root,COG4608@2|Bacteria,1NU4K@1224|Proteobacteria,1SKPD@1236|Gammaproteobacteria,1XTTK@135623|Vibrionales 135623|Vibrionales P COG4608 ABC-type oligopeptide transport system, ATPase component - - - ko:K02032 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - ABC_tran,oligo_HPY k141_31394_1 218284.CCDN010000002_gene2589 9.05e-71 226.0 COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,4HA31@91061|Bacilli,1ZB6P@1386|Bacillus 91061|Bacilli O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain htrA - 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Trypsin_2 k141_6611_2 1042377.AFPJ01000052_gene1588 1.43e-171 505.0 COG1629@1|root,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria,4651V@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec k141_17245_1 1307436.PBF_05148 4.56e-24 94.4 2E2UM@1|root,32XWN@2|Bacteria,1VDFF@1239|Firmicutes,4HJ3R@91061|Bacilli,1ZH6N@1386|Bacillus 91061|Bacilli S ATP synthase I chain atpI - - ko:K02116 - - - - ko00000,ko00194 3.A.2.1 - - ATP-synt_I k141_12709_1 1453501.JELR01000002_gene101 2.85e-83 262.0 COG3303@1|root,COG3303@2|Bacteria,1R5JF@1224|Proteobacteria,1S13K@1236|Gammaproteobacteria,4667Z@72275|Alteromonadaceae 1236|Gammaproteobacteria P Cytochrome c3 - - - - - - - - - - - - Cytochrom_C552,Cytochrom_c3_2 k141_9010_1 55601.VANGNB10_cII0536c 9.42e-06 47.0 28NYX@1|root,2ZBVY@2|Bacteria,1RA69@1224|Proteobacteria,1S1YX@1236|Gammaproteobacteria,1XWYY@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF1097) ycdZ - - - - - - - - - - - DUF1097 k141_5503_1 1461580.CCAS010000008_gene1211 5.55e-232 647.0 COG3039@1|root,COG3039@2|Bacteria,1TPFS@1239|Firmicutes,4HD09@91061|Bacilli,1ZEKY@1386|Bacillus 91061|Bacilli L COG3039 Transposase and inactivated derivatives, IS5 family - - - - - - - - - - - - DDE_Tnp_1,DDE_Tnp_1_6,DUF772 k141_7692_1 218284.CCDN010000007_gene3898 2.68e-90 270.0 COG1028@1|root,COG1028@2|Bacteria,1V0TV@1239|Firmicutes,4HF8Q@91061|Bacilli,1ZCCS@1386|Bacillus 91061|Bacilli IQ Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short k141_32591_1 349521.HCH_01694 4.44e-216 608.0 COG1757@1|root,COG1757@2|Bacteria,1MX0T@1224|Proteobacteria,1RN8E@1236|Gammaproteobacteria,1XHAY@135619|Oceanospirillales 135619|Oceanospirillales C Na H antiporter - - - - - - - - - - - - Na_H_antiporter k141_32591_2 1122197.ATWI01000012_gene615 5.23e-49 164.0 COG4461@1|root,COG4461@2|Bacteria,1R6Q3@1224|Proteobacteria,1S2QD@1236|Gammaproteobacteria,46BI6@72275|Alteromonadaceae 1236|Gammaproteobacteria S Membrane-bound lysozyme-inhibitor of c-type lysozyme - - - - - - - - - - - - LprI,MliC k141_10293_2 218284.CCDN010000001_gene662 6.65e-18 81.3 COG0053@1|root,COG0053@2|Bacteria,1TSGY@1239|Firmicutes,4H9WP@91061|Bacilli,1ZAPN@1386|Bacillus 91061|Bacilli P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family czcD - - - - - - - - - - - Cation_efflux,ZT_dimer k141_23335_1 1116375.VEJY3_22646 0.0 1243.0 COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,1RMYY@1236|Gammaproteobacteria,1XVUD@135623|Vibrionales 135623|Vibrionales M Mechanosensitive ion channel inner membrane domain 1 - - - ko:K22051 - - - - ko00000,ko02000 1.A.23.1.2,1.A.23.1.3 - - MS_channel,MscS_TM,MscS_porin k141_23335_2 1116375.VEJY3_21256 2.62e-112 331.0 COG1566@1|root,COG1566@2|Bacteria,1MU7I@1224|Proteobacteria,1RPV2@1236|Gammaproteobacteria,1XUFT@135623|Vibrionales 135623|Vibrionales V Secretion protein - - - - - - - - - - - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 k141_16064_2 218284.CCDN010000006_gene3556 3.85e-170 482.0 COG2141@1|root,COG2141@2|Bacteria,1TPRS@1239|Firmicutes,4H9R2@91061|Bacilli,1ZB1E@1386|Bacillus 91061|Bacilli C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases yceB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - - - - - - - - - - Bac_luciferase k141_16064_3 218284.CCDN010000006_gene3554 1.24e-16 76.3 2EEF3@1|root,33893@2|Bacteria,1VEUA@1239|Firmicutes,4ICQN@91061|Bacilli,1ZBAX@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_27801_1 997296.PB1_03780 6.96e-64 206.0 COG1600@1|root,COG1600@2|Bacteria,1TP6Q@1239|Firmicutes,4HAEW@91061|Bacilli,1ZC1W@1386|Bacillus 91061|Bacilli C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) queG GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 ko:K18979 - - - - ko00000,ko01000,ko03016 - - - DUF1730,Fer4_16,HEAT_2 k141_774_1 561229.Dd1591_1050 2.05e-124 364.0 COG2207@1|root,COG2207@2|Bacteria 2|Bacteria K Transcriptional regulator - - - - - - - - - - - - AraC_binding,Cupin_2,HTH_18 k141_6612_1 926559.JoomaDRAFT_0306 2.73e-23 98.6 COG0566@1|root,COG0566@2|Bacteria,4NRUR@976|Bacteroidetes,1I2US@117743|Flavobacteriia 976|Bacteroidetes J tRNA rRNA methyltransferase, SpoU - - 2.1.1.185 ko:K03218 - - - - ko00000,ko01000,ko03009 - - - SpoU_methylase k141_12710_1 472759.Nhal_1619 1.08e-45 164.0 COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,1MW3N@1224|Proteobacteria,1RN6N@1236|Gammaproteobacteria,1X01G@135613|Chromatiales 135613|Chromatiales C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - 1.17.1.9 ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001,ko01000 - - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding k141_12710_2 1286106.MPL1_02548 1.91e-52 168.0 COG0437@1|root,COG0437@2|Bacteria,1MU5T@1224|Proteobacteria,1RRAN@1236|Gammaproteobacteria,461YS@72273|Thiotrichales 72273|Thiotrichales C 4Fe-4S dicluster domain - - - ko:K00124 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001 - - - Fer4_7 k141_25738_1 1453501.JELR01000001_gene2853 6.28e-101 306.0 COG0477@1|root,COG2814@2|Bacteria,1MVKJ@1224|Proteobacteria,1RMHJ@1236|Gammaproteobacteria,464EA@72275|Alteromonadaceae 1236|Gammaproteobacteria EGP Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family xylE GO:0003674,GO:0005215,GO:0005351,GO:0005402,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0008643,GO:0015075,GO:0015077,GO:0015078,GO:0015144,GO:0015145,GO:0015146,GO:0015148,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015519,GO:0015672,GO:0015749,GO:0015750,GO:0015753,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034219,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 - ko:K05548,ko:K08138,ko:K08139 ko04113,map04113 - - - ko00000,ko00001,ko02000 2.A.1.1,2.A.1.1.3,2.A.1.15 - iECIAI1_1343.ECIAI1_4259,iECSE_1348.ECSE_4322 Sugar_tr k141_11472_3 1042377.AFPJ01000036_gene1171 5.18e-23 95.5 COG3823@1|root,COG3823@2|Bacteria,1R9YU@1224|Proteobacteria,1RZ5N@1236|Gammaproteobacteria,4679T@72275|Alteromonadaceae 1236|Gammaproteobacteria O Glutamine cyclotransferase - - 2.3.2.5 ko:K00683 - - - - ko00000,ko01000 - - - Glu_cyclase_2 k141_37388_1 1122194.AUHU01000014_gene1136 8.2e-64 213.0 COG1009@1|root,COG1009@2|Bacteria,1MW9F@1224|Proteobacteria,1RN54@1236|Gammaproteobacteria,469HG@72275|Alteromonadaceae 1236|Gammaproteobacteria CP Proton-conducting membrane transporter - - 1.6.5.3 ko:K05577 ko00190,ko01100,map00190,map01100 M00145 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 - - - Proton_antipo_M,Proton_antipo_N k141_29122_1 1042377.AFPJ01000030_gene492 6.36e-72 226.0 COG0730@1|root,COG0730@2|Bacteria,1QRFH@1224|Proteobacteria,1RRFY@1236|Gammaproteobacteria,465YS@72275|Alteromonadaceae 1236|Gammaproteobacteria S Sulfite exporter TauE/SafE - - - - - - - - - - - - TauE k141_33961_1 926560.KE387023_gene3595 1.45e-26 113.0 COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,1WMBC@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus T AAA domain - - - - - - - - - - - - AAA_22,BTAD,TPR_12 k141_19725_1 1196031.ALEG01000039_gene1299 1.28e-29 112.0 2E6FV@1|root,33136@2|Bacteria,1VH2N@1239|Firmicutes,4HQRC@91061|Bacilli,1ZNHG@1386|Bacillus 91061|Bacilli S Phage tail assembly chaperone protein, TAC - - - - - - - - - - - - Phage_TAC_12 k141_27046_1 1294265.JCM21738_406 1.02e-85 258.0 COG1013@1|root,COG1013@2|Bacteria,1TQJ2@1239|Firmicutes,4HAA4@91061|Bacilli,1ZCCX@1386|Bacillus 91061|Bacilli C COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit korB - 1.2.7.11,1.2.7.3 ko:K00175 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - PFO_beta_C,TPP_enzyme_C k141_30215_1 1347369.CCAD010000042_gene892 1.79e-122 367.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,1ZBIW@1386|Bacillus 91061|Bacilli V COG1132 ABC-type multidrug transport system, ATPase and permease components mdlB - - ko:K06147,ko:K18890 ko02010,map02010 M00707 - - ko00000,ko00001,ko00002,ko02000 3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran k141_35181_1 218284.CCDN010000005_gene3438 2.22e-130 381.0 COG2056@1|root,COG2056@2|Bacteria,1TSRY@1239|Firmicutes,4HBK6@91061|Bacilli,1ZB9I@1386|Bacillus 91061|Bacilli S antiporter yuiF - - ko:K07084 - - - - ko00000,ko02000 2.A.8.1.12 - iSB619.SA_RS04585 Na_H_antiport_2,Na_H_antiporter k141_2938_1 218284.CCDN010000001_gene277 8.77e-132 387.0 COG4565@1|root,COG4565@2|Bacteria,1TS2Z@1239|Firmicutes,4HCJ5@91061|Bacilli,1ZANG@1386|Bacillus 91061|Bacilli KT transcriptional regulatory protein - - - - - - - - - - - - HTH_11 k141_16084_1 866895.HBHAL_4886 6.7e-80 265.0 COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,4HABE@91061|Bacilli,3NDEF@45667|Halobacillus 91061|Bacilli EF Carbamoyl-phosphate synthetase large chain, oligomerisation domain carB GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS k141_24426_1 1280001.BAOA01000043_gene1279 1.36e-34 122.0 COG1854@1|root,COG1854@2|Bacteria,1MWQF@1224|Proteobacteria,1RMDZ@1236|Gammaproteobacteria,1XUCG@135623|Vibrionales 135623|Vibrionales H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) luxS GO:0008150,GO:0009372,GO:0009987,GO:0044764,GO:0051704 4.4.1.21 ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 M00609 R01291 RC00069,RC01929 ko00000,ko00001,ko00002,ko01000 - - - LuxS k141_24426_2 1116375.VEJY3_13090 1.8e-289 792.0 COG4536@1|root,COG4536@2|Bacteria,1NZ99@1224|Proteobacteria,1RNCE@1236|Gammaproteobacteria,1XTJ9@135623|Vibrionales 135623|Vibrionales P Mg2 and Co2 transporter CorB yfjD - - - - - - - - - - - CBS,CorC_HlyC,DUF21 k141_6621_1 441769.ABFU01000066_gene1961 6.34e-32 115.0 COG1495@1|root,COG1495@2|Bacteria,1V79S@1239|Firmicutes,4HH9B@91061|Bacilli,1ZRVX@1386|Bacillus 91061|Bacilli O Required for disulfide bond formation in some proteins bdbC - - ko:K03611 - - - - ko00000,ko03110 5.A.2.1 - - DsbB k141_33962_1 933115.GPDM_02420 8.33e-74 234.0 COG0737@1|root,COG0737@2|Bacteria,1TPV2@1239|Firmicutes,4IIPM@91061|Bacilli,26H1C@186818|Planococcaceae 91061|Bacilli F Belongs to the 5'-nucleotidase family - - - - - - - - - - - - 5_nucleotid_C k141_36197_1 218284.CCDN010000001_gene1932 3.95e-187 535.0 COG1766@1|root,COG1766@2|Bacteria,1TRK0@1239|Firmicutes,4HBF0@91061|Bacilli,1ZAZN@1386|Bacillus 91061|Bacilli N The M ring may be actively involved in energy transduction fliF - - ko:K02409 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 - - YscJ_FliF,YscJ_FliF_C k141_36197_2 218284.CCDN010000001_gene1931 1.97e-106 315.0 COG1536@1|root,COG1536@2|Bacteria,1TP01@1239|Firmicutes,4HAFZ@91061|Bacilli,1ZAQU@1386|Bacillus 91061|Bacilli N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation fliG - - ko:K02410 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02035 - - - FliG_C,FliG_M,FliG_N k141_9039_2 1279017.AQYJ01000027_gene1715 2.23e-54 177.0 COG1657@1|root,COG1657@2|Bacteria,1R3VV@1224|Proteobacteria,1S0Z2@1236|Gammaproteobacteria,469FU@72275|Alteromonadaceae 1236|Gammaproteobacteria I Domain of unknown function (DUF4159) - - - - - - - - - - - - DUF4159 k141_18607_1 218284.CCDN010000006_gene3610 6.12e-101 296.0 COG1647@1|root,COG1647@2|Bacteria,1TQ7X@1239|Firmicutes,4HBE6@91061|Bacilli,1ZAVD@1386|Bacillus 91061|Bacilli S Carboxylesterase est GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0008150,GO:0008152,GO:0016020,GO:0016298,GO:0016787,GO:0016788,GO:0044238,GO:0071704 3.1.1.1 ko:K03928 - - - - ko00000,ko01000 - - - Hydrolase_4 k141_782_1 218284.CCDN010000001_gene645 8.12e-50 181.0 COG1388@1|root,COG1388@2|Bacteria,1VETU@1239|Firmicutes,4HP2D@91061|Bacilli,1ZD0H@1386|Bacillus 91061|Bacilli M spore coat assembly protein SafA safA GO:0003674,GO:0005488,GO:0005515,GO:0019899,GO:0051117 - ko:K06370 - - - - ko00000 - - - LysM k141_35182_1 1121091.AUMP01000003_gene2548 4.25e-59 187.0 2E5K5@1|root,330BC@2|Bacteria,1VC9N@1239|Firmicutes,4HM43@91061|Bacilli 91061|Bacilli S Siphovirus Gp157 - - - - - - - - - - - - Sipho_Gp157 k141_27821_1 1283337.B0ZSF0_BPHA1 1.37e-283 789.0 4QV9W@35237|dsDNA viruses no RNA stage,4QHV2@10662|Myoviridae 10662|Myoviridae S Phage terminase large subunit (GpA) - - - - - - - - - - - - - k141_27821_2 1283337.B0ZSF1_BPHA1 6.09e-60 191.0 4QH5T@10239|Viruses,4R0MY@35237|dsDNA viruses no RNA stage,4QU9Y@28883|Caudovirales,4QJ8D@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k141_27821_3 1283337.PORTL_BPHA1 3.35e-28 115.0 4QAZJ@10239|Viruses,4QX3R@35237|dsDNA viruses no RNA stage,4QPFF@28883|Caudovirales,4QJS9@10662|Myoviridae 10662|Myoviridae S virion assembly - - - - - - - - - - - - - k141_20772_1 218284.CCDN010000001_gene1119 8.19e-18 82.0 COG0128@1|root,COG0128@2|Bacteria,1TPIH@1239|Firmicutes,4HBHZ@91061|Bacilli,1ZBP0@1386|Bacillus 91061|Bacilli E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate aroA GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03460 RC00350 ko00000,ko00001,ko00002,ko01000 - - - EPSP_synthase k141_20772_2 218284.CCDN010000001_gene1118 2.66e-54 180.0 COG0287@1|root,COG0287@2|Bacteria,1TPXG@1239|Firmicutes,4HBI4@91061|Bacilli,1ZBVZ@1386|Bacillus 91061|Bacilli E prephenate dehydrogenase tyrA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.3.1.12 ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00025 R01728 RC00125 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU22610 ACT,PDH k141_37389_2 1196031.ALEG01000059_gene5512 2.23e-28 103.0 2EIRB@1|root,33CGR@2|Bacteria,1VFHX@1239|Firmicutes,4HP39@91061|Bacilli,1ZJ0H@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_11475_1 1042377.AFPJ01000022_gene1302 1.24e-68 227.0 COG1251@1|root,COG1251@2|Bacteria,1MW58@1224|Proteobacteria,1RNGY@1236|Gammaproteobacteria,4656K@72275|Alteromonadaceae 1236|Gammaproteobacteria C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family nirB - 1.7.1.15 ko:K00362 ko00910,ko01120,map00910,map01120 M00530 R00787 RC00176 ko00000,ko00001,ko00002,ko01000 - - - Fer2_BFD,NIR_SIR,NIR_SIR_ferr,Pyr_redox_2 k141_24428_1 218284.CCDN010000007_gene4013 9.56e-50 167.0 COG2385@1|root,COG2385@2|Bacteria,1TQSI@1239|Firmicutes,4HCE3@91061|Bacilli,1ZBNU@1386|Bacillus 91061|Bacilli D Stage II sporulation protein D spoIID GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 - ko:K06381 - - - - ko00000 - - - SpoIID k141_35184_1 1294265.JCM21738_1992 1.77e-84 249.0 COG3439@1|root,COG3439@2|Bacteria,1VA5R@1239|Firmicutes,4HITT@91061|Bacilli,1ZH19@1386|Bacillus 91061|Bacilli S Domain of unknown function DUF302 - - - - - - - - - - - - DUF302 k141_5518_1 1294265.JCM21738_5493 2.34e-58 188.0 COG0497@1|root,COG0497@2|Bacteria,1V4G3@1239|Firmicutes,4HHDM@91061|Bacilli,1ZH4B@1386|Bacillus 91061|Bacilli L Putative cell-wall binding lipoprotein ykyA - - - - - - - - - - - YkyA k141_16085_2 218284.CCDN010000001_gene1886 1.54e-78 234.0 COG0858@1|root,COG0858@2|Bacteria,1VA0P@1239|Firmicutes,4HII1@91061|Bacilli,1ZGB3@1386|Bacillus 91061|Bacilli J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA rbfA - - ko:K02834 - - - - ko00000,ko03009 - - - RBFA k141_24429_1 218284.CCDN010000007_gene3988 2.34e-36 127.0 COG4475@1|root,COG4475@2|Bacteria,1V3H0@1239|Firmicutes,4HH6F@91061|Bacilli,1ZFKM@1386|Bacillus 91061|Bacilli S Belongs to the UPF0340 family ywlG - - - - - - - - - - - DUF436 k141_6623_1 1396858.Q666_01925 2.03e-120 352.0 COG3384@1|root,COG3384@2|Bacteria,1MXJZ@1224|Proteobacteria,1RR5P@1236|Gammaproteobacteria,4664C@72275|Alteromonadaceae 1236|Gammaproteobacteria S Catalytic LigB subunit of aromatic ring-opening dioxygenase - - - - - - - - - - - - LigB k141_27049_1 218284.CCDN010000005_gene3385 2.16e-160 457.0 COG0520@1|root,COG0520@2|Bacteria,1TQ1W@1239|Firmicutes,4HA6Z@91061|Bacilli,1ZB79@1386|Bacillus 91061|Bacilli E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine sufS - 2.8.1.7,4.4.1.16 ko:K11717 ko00450,ko01100,map00450,map01100 - R03599,R11528 RC00961,RC01789,RC02313 ko00000,ko00001,ko01000 - - - Aminotran_5 k141_27049_2 1033734.CAET01000034_gene4345 4.99e-08 53.1 COG0719@1|root,COG0719@2|Bacteria,1TRT0@1239|Firmicutes,4HB6W@91061|Bacilli,1ZATY@1386|Bacillus 91061|Bacilli O assembly protein SufD sufD - - ko:K07033,ko:K09015 - - - - ko00000 - - - UPF0051 k141_10320_1 218284.CCDN010000001_gene170 2.6e-93 290.0 COG2304@1|root,COG2304@2|Bacteria,1V0C8@1239|Firmicutes,4HDR1@91061|Bacilli,1ZCG8@1386|Bacillus 91061|Bacilli S Aerotolerance regulator N-terminal - - - - - - - - - - - - BatA,VWA_2 k141_10320_2 218284.CCDN010000001_gene169 9.45e-69 232.0 COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria,1TQXZ@1239|Firmicutes,4HB0B@91061|Bacilli,1ZDEG@1386|Bacillus 91061|Bacilli S von Willebrand factor type A domain - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - GATase1_like,VWA,VWA_2,VWA_3 k141_12732_1 1117379.BABA_19536 1.86e-24 93.2 2DPPC@1|root,332VC@2|Bacteria,1VM0N@1239|Firmicutes,4HNHT@91061|Bacilli,1ZIVE@1386|Bacillus 91061|Bacilli S Phospholipase_D-nuclease N-terminal yxlE - - - - - - - - - - - PLDc_N k141_12732_2 883103.HMPREF9703_01522 8.45e-10 59.7 COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,4H9MS@91061|Bacilli,27FQQ@186828|Carnobacteriaceae 91061|Bacilli E Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system potA - 3.6.3.30,3.6.3.31 ko:K02010,ko:K11072 ko02010,map02010 M00190,M00299 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.10,3.A.1.11.1 - iSB619.SA_RS05380 ABC_tran,TOBE_2 k141_783_1 1042377.AFPJ01000012_gene1375 1.79e-51 171.0 COG2771@1|root,COG2771@2|Bacteria,1QW0I@1224|Proteobacteria,1T5AY@1236|Gammaproteobacteria 1236|Gammaproteobacteria K helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE k141_35185_1 218284.CCDN010000005_gene3424 4.79e-75 228.0 COG0702@1|root,COG0702@2|Bacteria,1TQFS@1239|Firmicutes,4HDA2@91061|Bacilli,1ZBH3@1386|Bacillus 91061|Bacilli GM NmrA-like family yhfK_2 - - - - - - - - - - - NAD_binding_10 k141_36198_1 218284.CCDN010000001_gene1891 4.4e-107 317.0 COG0195@1|root,COG0195@2|Bacteria,1TPB3@1239|Firmicutes,4HA7F@91061|Bacilli,1ZDAH@1386|Bacillus 91061|Bacilli K Participates in both transcription termination and antitermination nusA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K02600 - - - - ko00000,ko03009,ko03021 - - - KH_5,NusA_N,S1 k141_22340_1 745411.B3C1_10902 4e-79 242.0 COG2186@1|root,COG2186@2|Bacteria,1MV83@1224|Proteobacteria,1RXBG@1236|Gammaproteobacteria,1JB9B@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria K FCD - - - - - - - - - - - - FCD,GntR k141_27983_2 373994.Riv7116_5177 1.54e-51 180.0 COG0464@1|root,COG0464@2|Bacteria,1G1YA@1117|Cyanobacteria,1HMQN@1161|Nostocales 1117|Cyanobacteria O PFAM ATPase family associated with various cellular activities (AAA) - - - - - - - - - - - - AAA k141_7944_1 218284.CCDN010000001_gene94 1.36e-62 207.0 COG4365@1|root,COG4365@2|Bacteria,1TQ2P@1239|Firmicutes,4HA2Z@91061|Bacilli,1ZBMV@1386|Bacillus 91061|Bacilli S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH bshC - - ko:K22136 - - - - ko00000 - - - BshC k141_37562_1 1279017.AQYJ01000026_gene375 3.61e-167 483.0 COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,1RNAZ@1236|Gammaproteobacteria,464M5@72275|Alteromonadaceae 1236|Gammaproteobacteria L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseA GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494 3.1.11.6 ko:K03601 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_L,tRNA_anti_2 k141_32875_1 1042377.AFPJ01000032_gene2773 1.97e-19 87.0 COG5339@1|root,COG5339@2|Bacteria,1QPEJ@1224|Proteobacteria,1SJ4D@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Bacterial protein of unknown function (DUF945) - - - - - - - - - - - - DUF945 k141_32875_2 1042377.AFPJ01000032_gene2774 2.38e-45 147.0 COG3671@1|root,COG3671@2|Bacteria,1MZMW@1224|Proteobacteria,1SF8E@1236|Gammaproteobacteria,46CD6@72275|Alteromonadaceae 1236|Gammaproteobacteria S membrane - - - - - - - - - - - - - k141_3172_2 506534.Rhein_1908 1.15e-158 478.0 COG0582@1|root,COG0582@2|Bacteria,1MV71@1224|Proteobacteria,1RQMW@1236|Gammaproteobacteria 1236|Gammaproteobacteria L integrase family - - - - - - - - - - - - Phage_Integr_2 k141_6931_1 218284.CCDN010000005_gene3246 3.96e-105 316.0 COG0534@1|root,COG0534@2|Bacteria,1TQMT@1239|Firmicutes,4H9Y2@91061|Bacilli,1ZBQK@1386|Bacillus 91061|Bacilli V Mate efflux family protein yisQ - - - - - - - - - - - MatE k141_1900_1 1121085.AUCI01000013_gene2608 1.16e-77 247.0 COG1252@1|root,COG1252@2|Bacteria,1UY7H@1239|Firmicutes,4HF9C@91061|Bacilli,1ZMS6@1386|Bacillus 91061|Bacilli C Pyridine nucleotide-disulphide oxidoreductase - - 1.6.99.3 ko:K03885 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - Pyr_redox_2 k141_11709_1 997296.PB1_09507 1.22e-66 207.0 COG0040@1|root,COG0040@2|Bacteria,1TSVZ@1239|Firmicutes,4H9MH@91061|Bacilli,1ZCFW@1386|Bacillus 91061|Bacilli E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity hisG GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002,ko01000 - - - HisG,tRNA-synt_His k141_11709_2 218284.CCDN010000006_gene3642 1.98e-12 66.6 COG0141@1|root,COG0141@2|Bacteria,1TPAW@1239|Firmicutes,4H9XK@91061|Bacilli,1ZCAX@1386|Bacillus 91061|Bacilli E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine hisD GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01158,R01163,R03012 RC00099,RC00242,RC00463 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU34910 Histidinol_dh k141_18969_1 398511.BpOF4_11500 1.34e-66 217.0 COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HB3V@91061|Bacilli,1ZB8V@1386|Bacillus 91061|Bacilli IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - ko:K00666 - - - - ko00000,ko01000,ko01004 - - - AMP-binding,AMP-binding_C k141_18969_2 441769.ABFU01000066_gene1911 3.25e-127 363.0 COG1584@1|root,COG1584@2|Bacteria,1TSYX@1239|Firmicutes,4HDC3@91061|Bacilli,1ZR9J@1386|Bacillus 91061|Bacilli S GPR1/FUN34/yaaH family - - - ko:K07034 - - - - ko00000 - - - Grp1_Fun34_YaaH k141_24661_1 218284.CCDN010000001_gene1812 1.18e-129 380.0 COG0161@1|root,COG0161@2|Bacteria,1TP9N@1239|Firmicutes,4HAA5@91061|Bacilli,1ZAUQ@1386|Bacillus 91061|Bacilli E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - - - - - - - - - - Aminotran_3 k141_31508_2 1116375.VEJY3_08010 7.69e-129 367.0 2CJ6B@1|root,32S9B@2|Bacteria,1N2I4@1224|Proteobacteria,1S8Z8@1236|Gammaproteobacteria,1XWS0@135623|Vibrionales 135623|Vibrionales S Thermostable hemolysin - - - - - - - - - - - - T_hemolysin k141_31508_3 1283284.AZUK01000001_gene1369 6.92e-25 98.6 294FR@1|root,2ZRVI@2|Bacteria,1PA4W@1224|Proteobacteria,1SVE5@1236|Gammaproteobacteria,1Y687@135624|Aeromonadales 135624|Aeromonadales - - - - - - - - - - - - - - - k141_31508_4 196367.JNFG01000007_gene6740 1.43e-42 148.0 COG4094@1|root,COG4094@2|Bacteria,1RDHB@1224|Proteobacteria,2VQBI@28216|Betaproteobacteria,1K76V@119060|Burkholderiaceae 28216|Betaproteobacteria S NnrU protein nnrU - - - - - - - - - - - NnrU k141_31508_5 1116375.VEJY3_20476 2.47e-63 199.0 COG1514@1|root,COG1514@2|Bacteria,1NJ1S@1224|Proteobacteria,1TIBH@1236|Gammaproteobacteria,1XYTD@135623|Vibrionales 135623|Vibrionales J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester - - 3.1.4.58 ko:K01975 - - - - ko00000,ko01000,ko03016 - - - LigT_PEase k141_31508_6 1116375.VEJY3_07070 2.44e-182 509.0 COG1793@1|root,COG1793@2|Bacteria,1MUW3@1224|Proteobacteria,1S2JP@1236|Gammaproteobacteria,1XTX8@135623|Vibrionales 135623|Vibrionales L DNA ligase - - 6.5.1.1,6.5.1.6,6.5.1.7 ko:K10747 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00381,R00382,R10822,R10823 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - - DNA_ligase_A_M,DNA_ligase_OB_2 k141_31508_7 1116375.VEJY3_07075 2.33e-176 499.0 28Q0R@1|root,2ZCJH@2|Bacteria,1RCAM@1224|Proteobacteria,1S3AM@1236|Gammaproteobacteria,1XSX4@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF3080) VP1478 - - - - - - - - - - - DUF3080 k141_31508_8 1116375.VEJY3_07080 2.15e-299 820.0 COG0534@1|root,COG0534@2|Bacteria,1MUAM@1224|Proteobacteria,1RP5M@1236|Gammaproteobacteria,1XUSY@135623|Vibrionales 135623|Vibrionales V Multidrug efflux pump norM GO:0003674,GO:0005215,GO:0006810,GO:0006855,GO:0008150,GO:0015238,GO:0015893,GO:0022857,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0046677,GO:0050896,GO:0051179,GO:0051234,GO:0055085 - ko:K03327 - - - - ko00000,ko02000 2.A.66.1 - - MatE k141_31508_9 223926.28806471 1.09e-124 357.0 COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,1RMSY@1236|Gammaproteobacteria,1XT06@135623|Vibrionales 135623|Vibrionales H Riboflavin synthase alpha chain ribE - 2.5.1.9 ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00066 RC00958,RC00960 ko00000,ko00001,ko00002,ko01000 - - - Lum_binding k141_31508_10 1116375.VEJY3_07090 4.11e-45 145.0 2DPBN@1|root,331EB@2|Bacteria,1NA64@1224|Proteobacteria,1SCQN@1236|Gammaproteobacteria,1XYZV@135623|Vibrionales 135623|Vibrionales S Cysteine-rich CPXCG - - - - - - - - - - - - Cys_rich_CPXG k141_31508_11 1116375.VEJY3_07095 5.7e-201 557.0 COG3001@1|root,COG3001@2|Bacteria,1MVHX@1224|Proteobacteria,1RRC5@1236|Gammaproteobacteria,1XSBA@135623|Vibrionales 135623|Vibrionales G COG3001 Fructosamine-3-kinase - GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237 - - - - - - - - - - Fructosamin_kin k141_31508_12 674977.VMC_40300 3.29e-196 550.0 COG1776@1|root,COG2201@1|root,COG1776@2|Bacteria,COG2201@2|Bacteria,1P5BV@1224|Proteobacteria,1RN5X@1236|Gammaproteobacteria,1XUEQ@135623|Vibrionales 135623|Vibrionales T COG0784 FOG CheY-like receiver - - - - - - - - - - - - Response_reg k141_31508_13 223926.28806474 1.1e-194 544.0 COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,1RPR0@1236|Gammaproteobacteria,1XUU1@135623|Vibrionales 135623|Vibrionales T COG2199 FOG GGDEF domain VP1483 - - - - - - - - - - - GGDEF,PAS k141_31508_14 223926.28806475 4.22e-70 212.0 2B806@1|root,3217S@2|Bacteria,1RHQE@1224|Proteobacteria,1S7AC@1236|Gammaproteobacteria,1XXB8@135623|Vibrionales 135623|Vibrionales S COG0187 Type IIA topoisomerase (DNA gyrase topo II, topoisomerase IV), B subunit SO2891 - - - - - - - - - - - DUF3802 k141_31508_15 223926.28806476 2.9e-73 225.0 COG0791@1|root,COG0791@2|Bacteria,1N0EE@1224|Proteobacteria,1RR2X@1236|Gammaproteobacteria,1XXUQ@135623|Vibrionales 135623|Vibrionales M COG0791 Cell wall-associated hydrolases (invasion-associated proteins) nlpC - - - - - - - - - - - NLPC_P60 k141_31508_16 1116375.VEJY3_07120 3.59e-266 753.0 COG0840@1|root,COG0840@2|Bacteria,1RCN5@1224|Proteobacteria,1S2HR@1236|Gammaproteobacteria,1XSW3@135623|Vibrionales 135623|Vibrionales NT methyl-accepting chemotaxis protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - MCPsignal k141_31508_17 223926.28806481 1.89e-51 166.0 2AGYY@1|root,3177S@2|Bacteria,1QFKA@1224|Proteobacteria,1SSY8@1236|Gammaproteobacteria,1Y0R0@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_31508_18 1280001.BAOA01000115_gene93 7.44e-157 444.0 COG3000@1|root,COG3000@2|Bacteria,1MW5G@1224|Proteobacteria,1RQJQ@1236|Gammaproteobacteria,1XTMI@135623|Vibrionales 135623|Vibrionales I Sterol desaturase - - - - - - - - - - - - FA_hydroxylase k141_31508_19 1280001.BAOA01000115_gene92 8.95e-151 427.0 COG3148@1|root,COG3148@2|Bacteria,1N8XY@1224|Proteobacteria,1RS6H@1236|Gammaproteobacteria,1XV59@135623|Vibrionales 135623|Vibrionales S DTW - - - ko:K05812 - - - - ko00000 - - - DTW k141_31508_20 1116375.VEJY3_07140 3.76e-213 589.0 COG1940@1|root,COG1940@2|Bacteria,1MU94@1224|Proteobacteria,1RNHE@1236|Gammaproteobacteria,1XSU2@135623|Vibrionales 135623|Vibrionales F Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P nagK - 2.7.1.59 ko:K00884 ko00520,ko01100,map00520,map01100 - R01201 RC00002,RC00017 ko00000,ko00001,ko01000 - - - ROK k141_31508_21 1116375.VEJY3_07145 1.6e-74 227.0 2E3X2@1|root,32YU8@2|Bacteria,1NE6S@1224|Proteobacteria,1SF7N@1236|Gammaproteobacteria,1XZBX@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_31508_22 1280001.BAOA01000115_gene89 1.06e-51 163.0 2CBU7@1|root,32ZCT@2|Bacteria,1N85K@1224|Proteobacteria,1SCKM@1236|Gammaproteobacteria,1XYDW@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF2960) SO1372 - - - - - - - - - - - DUF2960 k141_31508_23 223926.28806487 0.0 1058.0 COG0303@1|root,COG1763@1|root,COG0303@2|Bacteria,COG1763@2|Bacteria,1MVD5@1224|Proteobacteria,1RMQU@1236|Gammaproteobacteria,1XU88@135623|Vibrionales 135623|Vibrionales H Molybdopterin-guanine dinucleotide biosynthesis protein - - 2.10.1.1 ko:K03750 ko00790,ko01100,map00790,map01100 - R09735 RC03462 ko00000,ko00001,ko01000 - - - MoCF_biosynth,MobB,MoeA_C,MoeA_N k141_31508_24 1116375.VEJY3_07160 4.4e-136 385.0 COG0746@1|root,COG0746@2|Bacteria,1RH3M@1224|Proteobacteria,1S74N@1236|Gammaproteobacteria,1XSWW@135623|Vibrionales 135623|Vibrionales H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor mobA GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.77 ko:K03752 ko00790,ko01100,map00790,map01100 - R11581 - ko00000,ko00001,ko01000 - - - NTP_transf_3 k141_31508_26 223926.28806489 1.59e-153 433.0 COG1122@1|root,COG1122@2|Bacteria,1RHNX@1224|Proteobacteria,1S724@1236|Gammaproteobacteria,1XSTH@135623|Vibrionales 135623|Vibrionales P COG1122 ABC-type cobalt transport system, ATPase component - - 3.6.3.55 ko:K06857 ko02010,map02010 M00186 R10531 RC00002 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.6.2,3.A.1.6.4 - - ABC_tran k141_31508_27 1116375.VEJY3_07170 2.85e-148 419.0 COG4662@1|root,COG4662@2|Bacteria,1MZVS@1224|Proteobacteria,1RYSQ@1236|Gammaproteobacteria,1XU2M@135623|Vibrionales 135623|Vibrionales P COG4662 ABC-type tungstate transport system, periplasmic component - - - ko:K05773 ko02010,map02010 M00186 - - ko00000,ko00001,ko00002,ko02000 3.A.1.6.2,3.A.1.6.4 - - BPD_transp_1 k141_31508_28 1116375.VEJY3_07175 8.67e-188 522.0 COG2998@1|root,COG2998@2|Bacteria,1MVSF@1224|Proteobacteria,1RZ6B@1236|Gammaproteobacteria,1XSRY@135623|Vibrionales 135623|Vibrionales H COG2998 ABC-type tungstate transport system, permease component tupA - - ko:K05772 ko02010,map02010 M00186 - - ko00000,ko00001,ko00002,ko02000 3.A.1.6.2,3.A.1.6.4 - - PBP_like_2 k141_31508_29 223926.28806493 1.88e-309 848.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1XTA5@135623|Vibrionales 135623|Vibrionales T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - - - - - - - - - - HTH_8,Response_reg,Sigma54_activat k141_31508_30 1116375.VEJY3_07185 0.0 1192.0 COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RQZD@1236|Gammaproteobacteria,1XU16@135623|Vibrionales 135623|Vibrionales T COG0642 Signal transduction histidine kinase - - 2.7.13.3 ko:K02482 - - - - ko00000,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,sCache_3_3 k141_31508_31 1116375.VEJY3_07190 0.0 1038.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPN9@1236|Gammaproteobacteria,1XSW1@135623|Vibrionales 135623|Vibrionales S COG0488 ATPase components of ABC transporters with duplicated ATPase domains ybiT - - - - - - - - - - - ABC_tran,ABC_tran_Xtn k141_31508_33 1219076.N646_0561 3.53e-188 523.0 COG1526@1|root,COG1526@2|Bacteria,1MY28@1224|Proteobacteria,1RYH6@1236|Gammaproteobacteria,1XSXG@135623|Vibrionales 135623|Vibrionales C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH fdhD - - ko:K02379 - - - - ko00000 - - - FdhD-NarQ k141_31508_34 1116375.VEJY3_07205 2.89e-92 271.0 2E51T@1|root,30TP9@2|Bacteria,1QXDV@1224|Proteobacteria,1T39F@1236|Gammaproteobacteria,1XY6F@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF3305) - - - - - - - - - - - - DUF3305 k141_31508_35 575788.VS_1489 2.63e-40 144.0 2DNW4@1|root,32ZGA@2|Bacteria,1N7ZK@1224|Proteobacteria,1SI4F@1236|Gammaproteobacteria,1XY8V@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF3306) - - - - - - - - - - - - DUF3306 k141_31508_36 1219076.N646_0564 3.35e-75 240.0 COG1145@1|root,COG1145@2|Bacteria,1MWHY@1224|Proteobacteria,1RP5W@1236|Gammaproteobacteria,1XTHA@135623|Vibrionales 135623|Vibrionales C 4Fe-4S dicluster domain - - - - - - - - - - - - Fer4,Fer4_7 k141_35462_1 218284.CCDN010000001_gene133 3.51e-36 132.0 COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,4HAEV@91061|Bacilli,1ZBDZ@1386|Bacillus 91061|Bacilli D Belongs to the SEDS family ftsW - - ko:K03588 ko04112,map04112 - - - ko00000,ko00001,ko02000,ko03036 2.A.103.1 - - FTSW_RODA_SPOVE k141_16309_1 218284.CCDN010000005_gene3275 1.32e-95 285.0 COG5504@1|root,COG5504@2|Bacteria,1UYP6@1239|Firmicutes,4HFSY@91061|Bacilli,1ZCYK@1386|Bacillus 91061|Bacilli O Zn-dependent protease yjaZ - - - - - - - - - - - DUF2268 k141_19001_2 1382305.AZUC01000045_gene1298 3.27e-38 132.0 COG0607@1|root,COG0607@2|Bacteria,1VB3C@1239|Firmicutes,4HKWP@91061|Bacilli,26FT3@186818|Planococcaceae 91061|Bacilli P Rhodanese Homology Domain - - - - - - - - - - - - Rhodanese k141_19001_3 1211814.CAPG01000077_gene3645 1.76e-38 131.0 COG0607@1|root,COG0607@2|Bacteria,1VES3@1239|Firmicutes,4HNRE@91061|Bacilli,1ZI0X@1386|Bacillus 91061|Bacilli P Rhodanese domain protein - - - - - - - - - - - - Rhodanese k141_19001_4 398511.BpOF4_10950 2.88e-29 109.0 COG2149@1|root,COG2149@2|Bacteria,1VEBE@1239|Firmicutes,4HP6Q@91061|Bacilli,1ZIBU@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF202) - - - ko:K00389 - - - - ko00000 - - - DUF202 k141_26006_1 1453501.JELR01000002_gene768 6.18e-304 834.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,465V5@72275|Alteromonadaceae 1236|Gammaproteobacteria C Aldehyde dehydrogenase family aldH - 1.2.1.54,1.2.1.99 ko:K09472,ko:K12254 ko00330,ko01100,map00330,map01100 M00136 R02549,R03177,R07417,R07418 RC00080 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_5278 Aldedh k141_24699_2 796606.BMMGA3_01740 1.47e-76 242.0 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4HBS1@91061|Bacilli,1ZCI4@1386|Bacillus 91061|Bacilli C Belongs to the aldehyde dehydrogenase family. RocA subfamily rocA - 1.2.1.88 ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 - R00245,R00707,R00708,R04444,R04445,R05051 RC00080,RC00216,RC00242,RC00255 ko00000,ko00001,ko01000 - - - Aldedh k141_17410_1 1116375.VEJY3_20416 2.05e-155 463.0 COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,1RMYC@1236|Gammaproteobacteria,1XW5H@135623|Vibrionales 135623|Vibrionales P Cation transporting ATPase, C-terminus - - - - - - - - - - - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase k141_24700_1 554065.XP_005850209.1 1.24e-45 162.0 COG0151@1|root,KOG0237@2759|Eukaryota,37QAB@33090|Viridiplantae,34ISC@3041|Chlorophyta 3041|Chlorophyta F AIR synthase related protein, C-terminal domain - - 6.3.3.1 ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04208 RC01100 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C k141_19970_2 1279017.AQYJ01000028_gene2139 1.94e-118 340.0 COG2236@1|root,COG2236@2|Bacteria,1MXS1@1224|Proteobacteria,1RPSD@1236|Gammaproteobacteria,46742@72275|Alteromonadaceae 1236|Gammaproteobacteria F Phosphoribosyl transferase domain - - - ko:K07101 - - - - ko00000 - - - Pribosyltran k141_19970_3 301.JNHE01000036_gene4322 5.82e-118 362.0 COG0515@1|root,COG0515@2|Bacteria,1MVEU@1224|Proteobacteria,1SYEH@1236|Gammaproteobacteria,1YFQM@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria KLT Protein tyrosine kinase - - 2.7.11.1 ko:K08884,ko:K11912 ko02025,ko03070,map02025,map03070 - - - ko00000,ko00001,ko01000,ko01001,ko02044 - - - Pkinase k141_3193_2 218284.CCDN010000011_gene4401 3.25e-118 342.0 COG1214@1|root,COG1214@2|Bacteria,1V4YX@1239|Firmicutes,4HHD7@91061|Bacilli,1ZC43@1386|Bacillus 91061|Bacilli O COG1214 Inactive homolog of metal-dependent proteases yeaZ GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 ko:K01409,ko:K14742 - - R10648 RC00070,RC00416 ko00000,ko01000,ko03016 - - - Peptidase_M22 k141_5744_1 545693.BMQ_0794 2.26e-98 294.0 COG2141@1|root,COG2141@2|Bacteria,1TT4S@1239|Firmicutes,4HBJB@91061|Bacilli,1ZDA1@1386|Bacillus 91061|Bacilli C Luciferase-like monooxygenase luxA_2 - - - - - - - - - - - Bac_luciferase k141_5744_2 218284.CCDN010000001_gene495 6.96e-28 109.0 COG0477@1|root,COG2814@2|Bacteria,1TQXU@1239|Firmicutes,4HAYB@91061|Bacilli,1ZQ77@1386|Bacillus 91061|Bacilli EGP -transporter ytbD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K19577 - - - - ko00000,ko02000 2.A.1.2.65 - - MFS_1,Sugar_tr k141_15084_2 518766.Rmar_1793 1.43e-19 89.7 COG2802@1|root,COG2802@2|Bacteria,4NEJU@976|Bacteroidetes,1FJ9M@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes S ATP-dependent protease La (LON) substrate-binding domain - - 3.4.21.53 ko:K01338,ko:K07157 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - LON_substr_bdg k141_22377_1 1453501.JELR01000002_gene1258 9.59e-145 438.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RS1Q@1236|Gammaproteobacteria,469PS@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_6976_1 218284.CCDN010000001_gene1076 5.16e-68 209.0 2EENU@1|root,338GN@2|Bacteria,1VK1A@1239|Firmicutes,4HNX3@91061|Bacilli,1ZC57@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2663) ypbF - - - - - - - - - - - DUF2663 k141_36359_1 1219076.N646_2217 6.08e-100 290.0 2AU0F@1|root,31JKB@2|Bacteria,1RGGF@1224|Proteobacteria,1S5B2@1236|Gammaproteobacteria,1XX7G@135623|Vibrionales 135623|Vibrionales S COG NOG14600 non supervised orthologous group - - - - - - - - - - - - - k141_37586_1 218284.CCDN010000005_gene3164 6.6e-84 254.0 COG4152@1|root,COG4152@2|Bacteria,1TR06@1239|Firmicutes,4H9RX@91061|Bacilli,1ZC9T@1386|Bacillus 91061|Bacilli S ABC transporter, ATP-binding protein yhaQ - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 k141_37586_2 997296.PB1_03485 8.93e-11 64.3 COG1668@1|root,COG1668@2|Bacteria,1TXRK@1239|Firmicutes,4HC9K@91061|Bacilli,1ZBM6@1386|Bacillus 91061|Bacilli CP COG1668 ABC-type Na efflux pump, permease component yhaP - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 k141_6977_1 384765.SIAM614_18069 4.85e-71 236.0 COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,2TRKK@28211|Alphaproteobacteria 28211|Alphaproteobacteria M mechanosensitive ion channel - - - ko:K05802 - - - - ko00000,ko02000 1.A.23.1.1 - - DUF3772,MS_channel,MscS_TM,MscS_porin k141_30366_1 1453501.JELR01000002_gene1373 8.78e-86 256.0 COG1952@1|root,COG1952@2|Bacteria,1RI75@1224|Proteobacteria,1S62H@1236|Gammaproteobacteria,4679N@72275|Alteromonadaceae 1236|Gammaproteobacteria U One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA secB GO:0002790,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006605,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0034613,GO:0042886,GO:0043952,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046903,GO:0046907,GO:0051082,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0072321 - ko:K03071 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03110 3.A.5 - - SecB k141_30366_2 1453501.JELR01000002_gene1372 4.9e-42 139.0 COG0695@1|root,COG0695@2|Bacteria,1N72P@1224|Proteobacteria,1SCA2@1236|Gammaproteobacteria,468F1@72275|Alteromonadaceae 1236|Gammaproteobacteria O Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins grxC - - ko:K03676 - - - - ko00000,ko03110 - - - Glutaredoxin k141_30366_3 1453501.JELR01000002_gene1371 1.29e-71 219.0 COG0607@1|root,COG0607@2|Bacteria,1MZ83@1224|Proteobacteria,1S8ZI@1236|Gammaproteobacteria,4680N@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0607 Rhodanese-related sulfurtransferase yibN GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.8.1.1,2.8.1.2 ko:K01011 ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122 - R01931,R03105,R03106 RC00214 ko00000,ko00001,ko01000 - - - Rhodanese k141_24702_1 1042377.AFPJ01000036_gene1191 8.75e-91 281.0 COG1752@1|root,COG1752@2|Bacteria,1MUI6@1224|Proteobacteria,1RN0G@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Patatin-like phospholipase - - - ko:K07001 - - - - ko00000 - - - Patatin k141_23716_2 1238450.VIBNISOn1_1670025 1.44e-279 768.0 COG1175@1|root,COG1175@2|Bacteria,1MXKR@1224|Proteobacteria,1RN6B@1236|Gammaproteobacteria,1XVI9@135623|Vibrionales 135623|Vibrionales P Binding-protein-dependent transport system inner membrane component - - - ko:K15771 ko02010,map02010 M00491 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.16,3.A.1.1.2 - - BPD_transp_1 k141_23716_3 1238450.VIBNISOn1_1670023 8.16e-181 505.0 COG3833@1|root,COG3833@2|Bacteria,1QA3Z@1224|Proteobacteria,1RQ00@1236|Gammaproteobacteria,1XW8X@135623|Vibrionales 135623|Vibrionales P Binding-protein-dependent transport system inner membrane component - - - ko:K15772 ko02010,map02010 M00491 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.16,3.A.1.1.2 - - BPD_transp_1 k141_23716_4 1238450.VIBNISOn1_1670022 2.64e-256 707.0 COG3867@1|root,COG3867@2|Bacteria,1R33X@1224|Proteobacteria,1RYK6@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Arabinogalactan endo-beta-1,4-galactanase ganB - 3.2.1.89 ko:K01224 - - - - ko00000,ko01000 - - - Glyco_hydro_53 k141_23716_5 1238450.VIBNISOn1_1670021 0.0 1076.0 COG1874@1|root,COG1874@2|Bacteria,1MUVR@1224|Proteobacteria,1RPW9@1236|Gammaproteobacteria 1236|Gammaproteobacteria G beta-galactosidase bglY - 3.2.1.23 ko:K12308 ko00052,map00052 - R01105 RC00452 ko00000,ko00001,ko01000 - - - Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M k141_11735_2 1219076.N646_3543 2.41e-42 141.0 2EG9Y@1|root,33A1R@2|Bacteria,1NMAJ@1224|Proteobacteria,1SHG1@1236|Gammaproteobacteria,1XZ0I@135623|Vibrionales 135623|Vibrionales S protein structure with unknown function - - - - - - - - - - - - DUF4144 k141_11735_3 1116375.VEJY3_16121 2.57e-113 326.0 COG3803@1|root,COG3803@2|Bacteria,1RHYI@1224|Proteobacteria,1S40A@1236|Gammaproteobacteria,1XWW8@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria - - - - - - - - - - - - DUF924 k141_11735_4 1116375.VEJY3_16126 0.0 1175.0 COG1164@1|root,COG1164@2|Bacteria,1MUYZ@1224|Proteobacteria,1RYXN@1236|Gammaproteobacteria,1XTZF@135623|Vibrionales 135623|Vibrionales E Peptidase family M3 - - - - - - - - - - - - Peptidase_M3 k141_12916_2 1279017.AQYJ01000028_gene2151 4.75e-212 590.0 COG2207@1|root,COG2207@2|Bacteria,1R4MG@1224|Proteobacteria,1RQ8P@1236|Gammaproteobacteria,467CQ@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG2207 AraC-type DNA-binding domain-containing proteins - - - - - - - - - - - - Arabinose_bd,HTH_18 k141_30579_1 1527444.ucyna2_00325 1.5e-19 83.2 COG0049@1|root,COG0049@2|Bacteria,1G4ZX@1117|Cyanobacteria 1117|Cyanobacteria J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA rps7 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02992 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S7 k141_30579_2 130081.XP_005705782.1 4.51e-48 170.0 COG0480@1|root,KOG0465@2759|Eukaryota 2759|Eukaryota J translation elongation factor activity - GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006996,GO:0007275,GO:0008144,GO:0008150,GO:0009507,GO:0009526,GO:0009532,GO:0009536,GO:0009570,GO:0009657,GO:0009658,GO:0009791,GO:0009845,GO:0009941,GO:0009987,GO:0016043,GO:0017076,GO:0030554,GO:0031967,GO:0031975,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0048046,GO:0048856,GO:0071840,GO:0090351,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K02355 - - - - ko00000,ko03012,ko03029 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 k141_17765_1 869213.JCM21142_134825 5.59e-27 106.0 COG3039@1|root,COG3039@2|Bacteria,4NZF7@976|Bacteroidetes,47WR7@768503|Cytophagia 976|Bacteroidetes L Transposase - - - - - - - - - - - - - k141_15278_1 218284.CCDN010000002_gene2237 1.9e-134 396.0 COG3275@1|root,COG3275@2|Bacteria,1VTXF@1239|Firmicutes,4H9Z1@91061|Bacilli,1ZBKQ@1386|Bacillus 91061|Bacilli T Histidine kinase lytS - 2.7.13.3 ko:K07704 ko02020,map02020 M00492 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - 5TM-5TMR_LYT,GAF_3,HATPase_c,His_kinase k141_10695_1 218284.CCDN010000008_gene4141 1.61e-92 278.0 COG1575@1|root,COG1575@2|Bacteria,1TSZV@1239|Firmicutes,4HA68@91061|Bacilli,1ZB6F@1386|Bacillus 91061|Bacilli H Belongs to the MenA family. Type 1 subfamily menA GO:0003674,GO:0003824,GO:0004659,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006775,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016765,GO:0032194,GO:0042180,GO:0042181,GO:0042362,GO:0042371,GO:0042373,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.74 ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R05617,R06858,R10757 RC02935,RC02936,RC03264 ko00000,ko00001,ko00002,ko01000,ko01006 - - - UbiA k141_37886_1 1169144.KB910947_gene3733 8.76e-59 196.0 COG0772@1|root,COG0772@2|Bacteria,1V1V4@1239|Firmicutes,4HCZ8@91061|Bacilli,1ZDCU@1386|Bacillus 91061|Bacilli D Belongs to the SEDS family - - - - - - - - - - - - FTSW_RODA_SPOVE k141_34456_1 1122194.AUHU01000003_gene2026 2.82e-58 192.0 COG1609@1|root,COG1609@2|Bacteria,1MVUR@1224|Proteobacteria,1RN8T@1236|Gammaproteobacteria,464K5@72275|Alteromonadaceae 1236|Gammaproteobacteria K transcriptional - - - ko:K02529,ko:K05499 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_1,Peripla_BP_3 k141_28303_1 218284.CCDN010000005_gene3367 3.71e-176 510.0 COG5002@1|root,COG5002@2|Bacteria,1VUBP@1239|Firmicutes,4HUPW@91061|Bacilli,1ZS15@1386|Bacillus 91061|Bacilli T Histidine kinase kinE - 2.7.13.3 ko:K13533 ko02020,map02020 M00485 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9 k141_3475_1 463191.SSEG_02948 1.16e-47 161.0 COG1028@1|root,COG1028@2|Bacteria,2GJU1@201174|Actinobacteria 201174|Actinobacteria IQ Short-chain dehydrogenase reductase sdr - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 k141_3475_2 309807.SRU_1436 1.09e-97 293.0 COG0428@1|root,COG0428@2|Bacteria,4NGQ8@976|Bacteroidetes,1FJI0@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes P ZIP Zinc transporter gufA - - ko:K07238 - - - - ko00000,ko02000 2.A.5.5 - - Zip k141_4657_2 218284.CCDN010000001_gene765 2.88e-55 178.0 COG2384@1|root,COG2384@2|Bacteria,1V3I4@1239|Firmicutes,4HHIM@91061|Bacilli,1ZE5B@1386|Bacillus 91061|Bacilli S SAM-dependent methyltransferase trmK GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.217 ko:K06967 - - - - ko00000,ko01000,ko03016 - - - TrmK k141_8093_2 1453501.JELR01000001_gene2448 3.1e-41 149.0 COG3047@1|root,COG3047@2|Bacteria 2|Bacteria - - ompW - - ko:K07275 - - - - ko00000 - - - OmpW k141_8093_3 1279017.AQYJ01000028_gene2451 5.21e-37 142.0 COG3468@1|root,COG3468@2|Bacteria,1R8WV@1224|Proteobacteria 1224|Proteobacteria MU outer membrane autotransporter barrel domain - - - ko:K19231 - - - - ko00000,ko02000 1.B.12 - - Autotransporter,Pertactin k141_4658_1 218284.CCDN010000003_gene2991 5.49e-101 307.0 COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,4HACG@91061|Bacilli,1ZBBF@1386|Bacillus 91061|Bacilli S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid yabM GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03328 - - - - ko00000 2.A.66.2 - - Polysacc_synt,Polysacc_synt_C k141_17768_1 1397696.KK211189_gene2440 1.79e-79 241.0 COG0664@1|root,COG0664@2|Bacteria,1V2E0@1239|Firmicutes,4HG8V@91061|Bacilli 91061|Bacilli T Cyclic nucleotide-binding protein - - - - - - - - - - - - HTH_Crp_2,cNMP_binding k141_30582_2 1453501.JELR01000002_gene576 2.87e-128 379.0 COG0559@1|root,COG0559@2|Bacteria,1MVND@1224|Proteobacteria,1RQXD@1236|Gammaproteobacteria,46515@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the binding-protein-dependent transport system permease family urtB - - ko:K11960 ko02010,map02010 M00323 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4.4,3.A.1.4.5 - - BPD_transp_2,HEAT_2 k141_21268_1 1453501.JELR01000002_gene1389 1.03e-121 356.0 COG2114@1|root,COG2114@2|Bacteria,1N41U@1224|Proteobacteria,1SB9D@1236|Gammaproteobacteria,469AN@72275|Alteromonadaceae 1236|Gammaproteobacteria T Pfam Adenylate and Guanylate cyclase catalytic domain - - - - - - - - - - - - - k141_37887_1 1294265.JCM21738_2409 1.83e-51 172.0 COG0772@1|root,COG0772@2|Bacteria,1TPGH@1239|Firmicutes,4HAV4@91061|Bacilli,1ZBSB@1386|Bacillus 91061|Bacilli D Belongs to the SEDS family rodA - - ko:K05837 - - - - ko00000,ko03036 - - - FTSW_RODA_SPOVE k141_37887_2 1294265.JCM21738_2411 4.21e-196 544.0 29SV9@1|root,30E1E@2|Bacteria,1V46E@1239|Firmicutes,4HI7R@91061|Bacilli,1ZD35@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_28305_1 218284.CCDN010000001_gene1365 9.96e-143 412.0 COG2223@1|root,COG2223@2|Bacteria,1TPTN@1239|Firmicutes,4HA7C@91061|Bacilli,1ZB21@1386|Bacillus 91061|Bacilli P COG0477 Permeases of the major facilitator superfamily fsr GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K08223 - - - - ko00000,ko02000 2.A.1.35 - - MFS_1 k141_15280_1 218284.CCDN010000008_gene4262 8.4e-134 385.0 COG1387@1|root,COG1387@2|Bacteria,1TQQX@1239|Firmicutes,4H9P1@91061|Bacilli,1ZCA3@1386|Bacillus 91061|Bacilli E COG1387 Histidinol phosphatase and related hydrolases of the PHP family hisK GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.15 ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R03013 RC00017 ko00000,ko00001,ko00002,ko01000 - - - PHP,PHP_C k141_21269_1 1305836.AXVE01000011_gene949 9.65e-37 134.0 COG1914@1|root,COG1914@2|Bacteria,1TP0Q@1239|Firmicutes,4HAYE@91061|Bacilli,26DX5@186818|Planococcaceae 91061|Bacilli P Mn2 and Fe2 transporters of the NRAMP family ycsG - - - - - - - - - - - Nramp k141_21269_2 265729.GS18_0205810 1.16e-47 162.0 COG1984@1|root,COG1984@2|Bacteria,1TR6U@1239|Firmicutes,4HACC@91061|Bacilli,1ZCFE@1386|Bacillus 91061|Bacilli E Allophanate hydrolase subunit 2 kipA - - ko:K06350 - - - - ko00000 - - - CT_A_B k141_28306_1 1453501.JELR01000002_gene476 3.53e-75 248.0 COG3525@1|root,COG3525@2|Bacteria,1MVDE@1224|Proteobacteria,1RMNI@1236|Gammaproteobacteria,465UJ@72275|Alteromonadaceae 1236|Gammaproteobacteria G Glycosyl hydrolase family 20, domain 2 nahA - 3.2.1.52 ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 M00079 R00022,R06004,R11316 RC00049 ko00000,ko00001,ko00002,ko01000,ko03110 - GH20 - CHB_HEX_C_1,Glyco_hydro_20,Glyco_hydro_20b k141_33191_2 1279017.AQYJ01000021_gene2856 1.05e-65 213.0 COG0738@1|root,COG0738@2|Bacteria,1MXDC@1224|Proteobacteria,1RQX9@1236|Gammaproteobacteria,4659F@72275|Alteromonadaceae 1236|Gammaproteobacteria G Major Facilitator Superfamily gluP - - ko:K02429 - - - - ko00000,ko02000 2.A.1.7 - - MFS_1 k141_3479_1 1453501.JELR01000002_gene324 1.84e-85 275.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria,4651V@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec k141_30583_1 218284.CCDN010000001_gene741 4.42e-170 478.0 COG1283@1|root,COG1283@2|Bacteria,1TP4K@1239|Firmicutes,4HAZ0@91061|Bacilli,1ZBHZ@1386|Bacillus 91061|Bacilli P COG1283 Na phosphate symporter yqeW - - ko:K03324 - - - - ko00000,ko02000 2.A.58.2 - - Na_Pi_cotrans k141_21270_1 218284.CCDN010000001_gene1601 6.91e-90 273.0 COG2070@1|root,COG2070@2|Bacteria,1TPC3@1239|Firmicutes,4H9T0@91061|Bacilli,1ZBXS@1386|Bacillus 91061|Bacilli S COG2070 Dioxygenases related to 2-nitropropane dioxygenase npd - 1.13.12.16 ko:K00459 ko00910,map00910 - R00025 RC02541,RC02759 ko00000,ko00001,ko01000 - - - NMO k141_37888_2 997296.PB1_13804 3.06e-34 123.0 COG0071@1|root,COG0071@2|Bacteria,1VDEZ@1239|Firmicutes,4HKDG@91061|Bacilli,1ZJEV@1386|Bacillus 91061|Bacilli O Belongs to the small heat shock protein (HSP20) family hspc4-1 - - - - - - - - - - - HSP20 k141_4659_1 697284.ERIC2_c26440 3.72e-21 105.0 COG4926@1|root,COG4926@2|Bacteria,1U67P@1239|Firmicutes,4HAN5@91061|Bacilli 91061|Bacilli L Phage minor structural protein - - - - - - - - - - - - Peptidase_S74,Prophage_tail k141_21271_1 1453501.JELR01000002_gene115 3.66e-57 202.0 COG0587@1|root,COG0587@2|Bacteria,1MUE4@1224|Proteobacteria,1RQA8@1236|Gammaproteobacteria,464B5@72275|Alteromonadaceae 1236|Gammaproteobacteria L DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase dnaE2 GO:0003674,GO:0003824,GO:0003887,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K14162 - - - - ko00000,ko01000,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon k141_4660_1 218284.CCDN010000006_gene3595 1.75e-112 330.0 COG1622@1|root,COG1622@2|Bacteria,1TPF6@1239|Firmicutes,4HA9J@91061|Bacilli,1ZB28@1386|Bacillus 91061|Bacilli C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I qoxA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009055,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015002,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0016491,GO:0016679,GO:0016682,GO:0017144,GO:0019637,GO:0019693,GO:0022857,GO:0022890,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1902600 1.10.3.12 ko:K02826 ko00190,ko01100,map00190,map01100 M00416 R09492 RC00819 ko00000,ko00001,ko00002,ko01000 3.D.4.1 - iSB619.SA_RS05175 COX2,COX2_TM k141_17770_2 1453501.JELR01000001_gene2391 2.15e-40 149.0 COG1629@1|root,COG1629@2|Bacteria,1MX4K@1224|Proteobacteria,1RP6B@1236|Gammaproteobacteria,464ZU@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec k141_33192_1 796606.BMMGA3_05580 1.95e-79 246.0 COG1024@1|root,COG1024@2|Bacteria,1UZHP@1239|Firmicutes,4HEEK@91061|Bacilli,1ZB0V@1386|Bacillus 91061|Bacilli I COG1024 Enoyl-CoA hydratase carnithine racemase - - - - - - - - - - - - ECH_1 k141_3481_2 863239.AFIZ01000010_gene1298 4.07e-10 65.1 COG0553@1|root,COG0553@2|Bacteria,2IBCV@201174|Actinobacteria,22RC1@1653|Corynebacteriaceae 201174|Actinobacteria KL Superfamily II DNA RNA helicases, SNF2 family helZ - - - - - - - - - - - DUF3670,Helicase_C,SNF2_N k141_30585_1 218284.CCDN010000002_gene2395 7.75e-102 305.0 2DBJR@1|root,2Z9N7@2|Bacteria,1TRSN@1239|Firmicutes,4HCDI@91061|Bacilli,1ZN92@1386|Bacillus 91061|Bacilli S Spore germination B3/ GerAC like, C-terminal - - - - - - - - - - - - Spore_GerAC k141_34462_1 203122.Sde_0598 1.48e-21 94.7 COG3507@1|root,COG3507@2|Bacteria,1NNX4@1224|Proteobacteria,1RYTM@1236|Gammaproteobacteria,4657H@72275|Alteromonadaceae 1236|Gammaproteobacteria G Belongs to the glycosyl hydrolase 43 family - - 3.2.1.37,3.2.1.55 ko:K01198,ko:K01209 ko00520,ko01100,map00520,map01100 - R01433,R01762 RC00467 ko00000,ko00001,ko01000 - GH43,GH51 - Glyco_hydro_43 k141_34462_2 326442.PSHAa1768 8.89e-78 248.0 COG4146@1|root,COG4146@2|Bacteria,1MXWV@1224|Proteobacteria,1RR4S@1236|Gammaproteobacteria,2Q5DM@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family sglT - - ko:K03307 - - - - ko00000 2.A.21 - - SSF k141_37889_1 1042377.AFPJ01000007_gene1923 4.35e-119 350.0 COG1716@1|root,COG1716@2|Bacteria,1RAA4@1224|Proteobacteria,1S3GK@1236|Gammaproteobacteria,4687T@72275|Alteromonadaceae 1236|Gammaproteobacteria T Forkhead associated domain - - - - - - - - - - - - FHA,Yop-YscD_cpl k141_37889_2 1279017.AQYJ01000025_gene749 8.27e-33 115.0 COG0526@1|root,33ARA@2|Bacteria 2|Bacteria CO COG0526, thiol-disulfide isomerase and thioredoxins - - - - - - - - - - - - DUF836 k141_21272_1 218284.CCDN010000001_gene1774 4.44e-182 513.0 COG1457@1|root,COG1457@2|Bacteria,1UI7R@1239|Firmicutes,4ISUV@91061|Bacilli 91061|Bacilli F Spore germination protein - - - - - - - - - - - - Spore_permease k141_8096_1 223926.28806263 9.84e-124 360.0 COG0010@1|root,COG0010@2|Bacteria,1NCRN@1224|Proteobacteria,1RNKI@1236|Gammaproteobacteria,1XV0K@135623|Vibrionales 135623|Vibrionales E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide hutG GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016813,GO:0019439,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0052803,GO:0052805,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.3.8 ko:K01479 ko00340,ko01100,map00340,map01100 M00045 R02285 RC00221,RC00681 ko00000,ko00001,ko00002,ko01000 - - - Arginase k141_4661_1 218284.CCDN010000001_gene728 2.47e-60 197.0 COG0860@1|root,COG0860@2|Bacteria,1TSFS@1239|Firmicutes,4HACZ@91061|Bacilli,1ZAV0@1386|Bacillus 91061|Bacilli M stage II sporulation protein P spoIIP - - ko:K06385 - - - - ko00000 - - - SpoIIP k141_4661_2 218284.CCDN010000001_gene727 5.04e-50 168.0 COG0680@1|root,COG0680@2|Bacteria,1TPFY@1239|Firmicutes,4HAGH@91061|Bacilli,1ZC4A@1386|Bacillus 91061|Bacilli C Initiates the rapid degradation of small, acid-soluble proteins during spore germination gpr GO:0000003,GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019954,GO:0030436,GO:0032502,GO:0043170,GO:0043934,GO:0044238,GO:0071704,GO:0140096,GO:1901564 3.4.24.78 ko:K06012 - - - - ko00000,ko01000,ko01002 - - - Peptidase_A25 k141_2260_1 1042377.AFPJ01000048_gene2684 3.5e-178 533.0 COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,1RSKR@1236|Gammaproteobacteria,46BA9@72275|Alteromonadaceae 1236|Gammaproteobacteria KLT Protein tyrosine kinase - - 2.7.11.1 ko:K08884,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - Pkinase,TPR_16,TPR_19,TPR_2,TPR_8 k141_2260_2 1423755.BAML01000004_gene439 1.82e-28 117.0 COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,4H9KD@91061|Bacilli,3F4G6@33958|Lactobacillaceae 91061|Bacilli KLT serine threonine protein kinase prkC GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 ko:K08884,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PASTA,Pkinase k141_28310_1 1217708.F887_01415 6.95e-13 68.6 COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,1RPQ7@1236|Gammaproteobacteria,3NJCE@468|Moraxellaceae 1236|Gammaproteobacteria I Glycerol-3-phosphate dehydrogenase gpsA GO:0003674,GO:0003824,GO:0004367,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006072,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0047952,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 - R00842,R00844 RC00029 ko00000,ko00001,ko01000 - - iJN746.PP_4169,iSFV_1184.SFV_3923 NAD_Gly3P_dh_C,NAD_Gly3P_dh_N k141_28310_2 1121448.DGI_1219 8.61e-15 75.9 COG0344@1|root,COG0344@2|Bacteria,1RD4Z@1224|Proteobacteria,42QQP@68525|delta/epsilon subdivisions,2WMZE@28221|Deltaproteobacteria,2MB51@213115|Desulfovibrionales 28221|Deltaproteobacteria I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP plsY - 2.3.1.15 ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - G3P_acyltransf k141_8097_1 218284.CCDN010000007_gene3955 7.87e-117 343.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,1ZBYG@1386|Bacillus 91061|Bacilli I Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation mmgA GO:0003674,GO:0003824,GO:0003988,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - iYO844.BSU24170 Thiolase_C,Thiolase_N k141_3482_2 1042377.AFPJ01000016_gene127 2.48e-33 121.0 COG0702@1|root,COG0702@2|Bacteria,1MZG7@1224|Proteobacteria,1S39N@1236|Gammaproteobacteria,4653X@72275|Alteromonadaceae 1236|Gammaproteobacteria GM Nucleoside-diphosphate-sugar epimerases - - - - - - - - - - - - Epimerase,NAD_binding_10 k141_16584_2 1116375.VEJY3_23056 3.66e-68 211.0 2DC7E@1|root,2ZD5M@2|Bacteria,1RC9H@1224|Proteobacteria,1S3D4@1236|Gammaproteobacteria,1XY6X@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_16584_3 754436.JCM19237_5388 1.19e-129 388.0 COG0741@1|root,COG0741@2|Bacteria,1MW2T@1224|Proteobacteria,1RM9N@1236|Gammaproteobacteria,1XSTN@135623|Vibrionales 135623|Vibrionales M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - - - - - - - - - - DUF3393,SLT k141_17811_1 218284.CCDN010000004_gene3141 1.18e-186 528.0 COG0114@1|root,COG0114@2|Bacteria,1UHPH@1239|Firmicutes,4HA6P@91061|Bacilli,1ZS23@1386|Bacillus 91061|Bacilli C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate fumC GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 M00009,M00011,M00173,M00376 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS09430 FumaraseC_C,Lyase_1 k141_21325_1 316274.Haur_0953 5.84e-46 153.0 COG0454@1|root,COG0456@2|Bacteria 2|Bacteria K acetyltransferase VY92_01935 - - - - - - - - - - - Acetyltransf_1 k141_8144_1 1247963.JPHU01000010_gene2183 5.23e-16 86.3 COG4206@1|root,COG4206@2|Bacteria,1QUGQ@1224|Proteobacteria 1224|Proteobacteria H COG1629 Outer membrane receptor proteins, mostly Fe transport - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_4702_1 471223.GWCH70_0609 9.38e-69 216.0 COG0619@1|root,COG0619@2|Bacteria,1TUDZ@1239|Firmicutes,4HER7@91061|Bacilli,1WHRN@129337|Geobacillus 91061|Bacilli P cobalt transport ykoC - - ko:K16785 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - CbiQ k141_33240_1 1116375.VEJY3_01575 4.68e-169 496.0 COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,1RMH7@1236|Gammaproteobacteria,1XUHS@135623|Vibrionales 135623|Vibrionales S transport system, fused permease components - - - - - - - - - - - - DUF3394,DctM k141_3501_1 1279017.AQYJ01000022_gene2756 8.59e-160 458.0 COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,1RN3R@1236|Gammaproteobacteria,464NA@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) gltX GO:0003674,GO:0003824,GO:0004812,GO:0004818,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006424,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.17 ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 - - iEC042_1314.EC042_2616 tRNA-synt_1c k141_2316_1 1116375.VEJY3_00175 2.05e-116 361.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1XSSQ@135623|Vibrionales 135623|Vibrionales V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K18138 ko01501,ko01503,map01501,map01503 M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2 - - ACR_tran k141_33241_1 1294265.JCM21738_4874 2.78e-100 297.0 COG0313@1|root,COG0313@2|Bacteria,1TP6U@1239|Firmicutes,4HAH8@91061|Bacilli,1ZBN1@1386|Bacillus 91061|Bacilli H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA rsmI GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 2.1.1.198 ko:K07056 - - - - ko00000,ko01000,ko03009 - - - TP_methylase k141_21326_2 1042377.AFPJ01000032_gene2719 2.2e-36 132.0 COG2267@1|root,COG2267@2|Bacteria,1RAQZ@1224|Proteobacteria,1S2YX@1236|Gammaproteobacteria,467BE@72275|Alteromonadaceae 1236|Gammaproteobacteria I Serine aminopeptidase, S33 pldB - 3.1.1.5 ko:K01048 ko00564,map00564 - - - ko00000,ko00001,ko01000 - - - Hydrolase_4 k141_17814_1 218284.CCDN010000001_gene90 3e-153 451.0 COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,4H9VQ@91061|Bacilli,1ZASE@1386|Bacillus 91061|Bacilli M Penicillin-binding Protein pbpX GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - - PASTA,PBP_dimer,Transpeptidase k141_28366_2 1453501.JELR01000002_gene130 0.0 1088.0 COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,1RMNZ@1236|Gammaproteobacteria,4641P@72275|Alteromonadaceae 1236|Gammaproteobacteria I Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA acsA GO:0003674,GO:0003824,GO:0003987,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006083,GO:0006084,GO:0006085,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006473,GO:0006476,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016054,GO:0016405,GO:0016787,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017001,GO:0017144,GO:0018130,GO:0018193,GO:0018205,GO:0018394,GO:0019213,GO:0019427,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033558,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034421,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0035601,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0043687,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0045733,GO:0046390,GO:0046395,GO:0046483,GO:0050218,GO:0051186,GO:0051188,GO:0055086,GO:0071616,GO:0071704,GO:0072329,GO:0072521,GO:0072522,GO:0090407,GO:0098732,GO:0140096,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 - - iE2348C_1286.E2348C_4392,iYL1228.KPN_04478 ACAS_N,AMP-binding,AMP-binding_C k141_37945_2 218284.CCDN010000001_gene966 6.86e-77 236.0 COG0190@1|root,COG0190@2|Bacteria,1TP1P@1239|Firmicutes,4H9Q6@91061|Bacilli,1ZC9G@1386|Bacillus 91061|Bacilli F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate folD GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R01220,R01655 RC00202,RC00578 ko00000,ko00001,ko00002,ko01000 - - - THF_DHG_CYH,THF_DHG_CYH_C k141_4704_1 218284.CCDN010000005_gene3186 4.01e-137 401.0 COG3069@1|root,COG3069@2|Bacteria,1TQ99@1239|Firmicutes,4H9Q2@91061|Bacilli,1ZCNB@1386|Bacillus 91061|Bacilli C membrane yhfA - - - - - - - - - - - - k141_8147_2 861299.J421_2672 4.15e-48 165.0 COG1899@1|root,COG1899@2|Bacteria 2|Bacteria O peptidyl-lysine modification to peptidyl-hypusine - - - - - - - - - - - - - k141_37946_1 218284.CCDN010000005_gene3484 2.45e-115 341.0 COG1820@1|root,COG1820@2|Bacteria,1TPFK@1239|Firmicutes,4HC6C@91061|Bacilli,1ZCM7@1386|Bacillus 91061|Bacilli G Belongs to the metallo-dependent hydrolases superfamily. NagA family nagA GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005515,GO:0006040,GO:0006044,GO:0006046,GO:0008150,GO:0008152,GO:0008448,GO:0009056,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046348,GO:0046872,GO:0046914,GO:0046983,GO:0071704,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901575 3.5.1.25 ko:K01443 ko00520,ko01130,map00520,map01130 - R02059 RC00166,RC00300 ko00000,ko00001,ko01000 - - - Amidohydro_1 k141_36620_1 223926.28806027 5.02e-228 628.0 COG0189@1|root,COG0189@2|Bacteria,1MVDU@1224|Proteobacteria,1RR7D@1236|Gammaproteobacteria,1XV35@135623|Vibrionales 135623|Vibrionales HJ COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase) PA1766 - - - - - - - - - - - ATPgrasp_ST k141_36620_2 223926.28806028 0.0 900.0 COG1305@1|root,COG1305@2|Bacteria,1MVV3@1224|Proteobacteria,1RRIA@1236|Gammaproteobacteria,1XSMI@135623|Vibrionales 135623|Vibrionales E 7 transmembrane helices usually fused to an inactive transglutaminase - - - - - - - - - - - - 7TM_transglut,Transglut_i_TM k141_36620_3 1116375.VEJY3_04855 9.81e-140 399.0 COG4067@1|root,COG4067@2|Bacteria,1N0VV@1224|Proteobacteria,1S5YG@1236|Gammaproteobacteria,1Y2PG@135623|Vibrionales 135623|Vibrionales O Putative ATP-dependant zinc protease - - - - - - - - - - - - Zn_protease k141_36620_4 223926.28806031 1.53e-243 667.0 COG0500@1|root,COG0500@2|Bacteria,1MVSK@1224|Proteobacteria,1RMQY@1236|Gammaproteobacteria,1XSY3@135623|Vibrionales 135623|Vibrionales J Catalyzes carboxymethyl transfer from carboxy-S- adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs cmoB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 - ko:K15257 - - - - ko00000,ko01000,ko03016 - - - Methyltransf_9 k141_32175_7 1042377.AFPJ01000036_gene1145 3.33e-105 326.0 COG1982@1|root,COG1982@2|Bacteria,1MWK4@1224|Proteobacteria,1RMVF@1236|Gammaproteobacteria,464W7@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG1982 Arginine lysine ornithine decarboxylases - - 4.1.1.19 ko:K01584,ko:K01585 ko00330,ko01100,map00330,map01100 M00133 R00566 RC00299 ko00000,ko00001,ko00002,ko01000 - - - OKR_DC_1,OKR_DC_1_C k141_2503_1 42565.FP66_03935 8.46e-191 561.0 COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,1RM9A@1236|Gammaproteobacteria,1XH4C@135619|Oceanospirillales 135619|Oceanospirillales D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins ftsK - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma k141_34600_1 1379698.RBG1_1C00001G1616 9.87e-05 48.1 COG0515@1|root,COG0515@2|Bacteria,2NQWH@2323|unclassified Bacteria 2|Bacteria KLT Protein tyrosine kinase - - - - - - - - - - - - Pkinase,TPR_8 k141_8475_1 1279017.AQYJ01000024_gene926 1.33e-224 620.0 COG0320@1|root,COG0320@2|Bacteria,1MVRD@1224|Proteobacteria,1RMAT@1236|Gammaproteobacteria,46447@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives lipA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 ko:K03644 ko00785,ko01100,map00785,map01100 - R07767,R07768 RC01978 ko00000,ko00001,ko01000 - - iAPECO1_1312.APECO1_1427,iB21_1397.B21_00586,iBWG_1329.BWG_0499,iE2348C_1286.E2348C_0528,iEC55989_1330.EC55989_0620,iECABU_c1320.ECABU_c06820,iECBD_1354.ECBD_3023,iECB_1328.ECB_00597,iECDH10B_1368.ECDH10B_0589,iECDH1ME8569_1439.ECDH1ME8569_0597,iECD_1391.ECD_00597,iECED1_1282.ECED1_0624,iECH74115_1262.ECH74115_0716,iECIAI1_1343.ECIAI1_0611,iECIAI39_1322.ECIAI39_0603,iECNA114_1301.ECNA114_0567,iECO103_1326.ECO103_0635,iECO111_1330.ECO111_0658,iECO26_1355.ECO26_0702,iECOK1_1307.ECOK1_0638,iECP_1309.ECP_0658,iECS88_1305.ECS88_0669,iECSE_1348.ECSE_0695,iECSF_1327.ECSF_0567,iECSP_1301.ECSP_0681,iECUMN_1333.ECUMN_0720,iECW_1372.ECW_m0682,iECs_1301.ECs0666,iEKO11_1354.EKO11_3238,iETEC_1333.ETEC_0656,iEcDH1_1363.EcDH1_2998,iEcE24377_1341.EcE24377A_0652,iEcHS_1320.EcHS_A0679,iEcSMS35_1347.EcSMS35_0648,iEcolC_1368.EcolC_3017,iG2583_1286.G2583_0791,iJO1366.b0628,iLF82_1304.LF82_1199,iNRG857_1313.NRG857_02855,iSBO_1134.SBO_0492,iSDY_1059.SDY_0550,iSF_1195.SF0653,iSFxv_1172.SFxv_0720,iSSON_1240.SSON_0582,iS_1188.S0675,iSbBS512_1146.SbBS512_E0542,iUMN146_1321.UM146_14375,iUMNK88_1353.UMNK88_663,iUTI89_1310.UTI89_C0631,iWFL_1372.ECW_m0682,iY75_1357.Y75_RS03275,ic_1306.c0718 LIAS_N,Radical_SAM k141_8475_4 1453501.JELR01000002_gene138 1.14e-229 637.0 COG1686@1|root,COG1686@2|Bacteria,1MUU7@1224|Proteobacteria,1RMJA@1236|Gammaproteobacteria,4646M@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the peptidase S11 family dacA GO:0000270,GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 3.4.16.4 ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - iEC55989_1330.EC55989_2269,iSFV_1184.SFV_0694,iSbBS512_1146.SbBS512_E2506,iYL1228.KPN_00664 PBP5_C,Peptidase_S11 k141_15602_2 1033734.CAET01000065_gene2279 5.58e-12 66.6 COG0591@1|root,COG0591@2|Bacteria,1TPVE@1239|Firmicutes,4H9KW@91061|Bacilli,1ZB64@1386|Bacillus 91061|Bacilli E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - ko:K11928 - - - - ko00000,ko02000 2.A.21.2 - - SSF k141_35750_1 441769.ABFU01000049_gene3702 1.59e-133 386.0 COG0672@1|root,COG0672@2|Bacteria,1TQIA@1239|Firmicutes,4HCJZ@91061|Bacilli,1ZDYA@1386|Bacillus 91061|Bacilli P COG0672 High-affinity Fe2 Pb2 permease - - - ko:K07243 - - - - ko00000,ko02000 2.A.108.1,2.A.108.2 - - FTR1 k141_29811_1 218284.CCDN010000001_gene169 9.03e-176 516.0 COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria,1TQXZ@1239|Firmicutes,4HB0B@91061|Bacilli,1ZDEG@1386|Bacillus 91061|Bacilli S von Willebrand factor type A domain - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - GATase1_like,VWA,VWA_2,VWA_3 k141_4876_1 1294265.JCM21738_3629 6.41e-29 103.0 29RXQ@1|root,30D20@2|Bacteria,1UAQ9@1239|Firmicutes,4IM2Y@91061|Bacilli,1ZIYI@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_10782_2 218284.CCDN010000002_gene2014 6.32e-59 182.0 COG0721@1|root,COG0721@2|Bacteria,1VEK3@1239|Firmicutes,4HNNA@91061|Bacilli,1ZH54@1386|Bacillus 91061|Bacilli J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatC - 6.3.5.6,6.3.5.7 ko:K02435 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Glu-tRNAGln k141_19125_1 1294265.JCM21738_3833 5.59e-125 365.0 COG0501@1|root,COG0501@2|Bacteria,1TRQE@1239|Firmicutes,4HD5G@91061|Bacilli,1ZC4F@1386|Bacillus 91061|Bacilli O Peptidase M48 yhfN GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0070011,GO:0071586,GO:0071704,GO:0080120,GO:0140096,GO:1901564 - - - - - - - - - - Peptidase_M48,Peptidase_M48_N k141_36929_2 1219072.VHA01S_028_00410 1.33e-127 370.0 28JU1@1|root,2Z9J4@2|Bacteria,1R7R9@1224|Proteobacteria,1RS2X@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - GIY-YIG k141_36929_4 1384049.CD29_03820 2.34e-44 172.0 COG0699@1|root,COG0699@2|Bacteria,1U97A@1239|Firmicutes,4IJ9N@91061|Bacilli,3IZJA@400634|Lysinibacillus 91061|Bacilli S Dynamin family - - - - - - - - - - - - Dynamin_N k141_23858_1 218284.CCDN010000002_gene2156 6.49e-118 368.0 COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,4HAFP@91061|Bacilli,1ZBJ3@1386|Bacillus 91061|Bacilli V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family swrC - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran k141_23858_2 218284.CCDN010000002_gene2164 1.68e-87 272.0 COG2244@1|root,COG2244@2|Bacteria,1VRYZ@1239|Firmicutes,4HV8Z@91061|Bacilli,1ZCGG@1386|Bacillus 91061|Bacilli S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid ykvU - - - - - - - - - - - MatE,Polysacc_synt,Polysacc_synt_C k141_17981_1 1116375.VEJY3_05400 2.21e-167 476.0 2C7MP@1|root,2Z7Q4@2|Bacteria,1NHK1@1224|Proteobacteria,1RQ17@1236|Gammaproteobacteria,1XTB8@135623|Vibrionales 135623|Vibrionales S COG0500 SAM-dependent methyltransferases PP0279 - - - - - - - - - - - Methyltransf_32 k141_17981_2 1116375.VEJY3_05405 1.7e-259 712.0 COG0686@1|root,COG0686@2|Bacteria,1QTX1@1224|Proteobacteria,1T1JB@1236|Gammaproteobacteria,1XU10@135623|Vibrionales 135623|Vibrionales C Belongs to the AlaDH PNT family ald - 1.4.1.1 ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 - R00396 RC00008 ko00000,ko00001,ko01000 - - - AlaDh_PNT_C,AlaDh_PNT_N k141_17981_3 1280001.BAOA01000027_gene4826 4.96e-111 319.0 COG1522@1|root,COG1522@2|Bacteria,1MX7R@1224|Proteobacteria,1RPGA@1236|Gammaproteobacteria,1XVIW@135623|Vibrionales 135623|Vibrionales K COG1522 Transcriptional regulators lrp - - ko:K03719 - - - - ko00000,ko03000,ko03036 - - - AsnC_trans_reg,HTH_24 k141_17981_4 1116375.VEJY3_05415 0.0 1296.0 COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,1RM9A@1236|Gammaproteobacteria,1XUE7@135623|Vibrionales 135623|Vibrionales D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins ftsK - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma k141_11982_2 198467.NP92_01710 3.09e-48 162.0 COG0861@1|root,COG0861@2|Bacteria,1TQ09@1239|Firmicutes,4HB99@91061|Bacilli,21WXT@150247|Anoxybacillus 91061|Bacilli P Integral membrane protein TerC family ykoY - - - - - - - - - - - TerC k141_6079_2 406124.ACPC01000019_gene2933 2.76e-39 134.0 2E5BC@1|root,3303G@2|Bacteria,1VCID@1239|Firmicutes,4HMCQ@91061|Bacilli,1ZHCG@1386|Bacillus 91061|Bacilli S Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth gvpJ - - - - - - - - - - - Gas_vesicle k141_32176_1 218284.CCDN010000002_gene2271 1.78e-63 203.0 COG1902@1|root,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,4HAS5@91061|Bacilli,1ZB1N@1386|Bacillus 91061|Bacilli C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family yqiG - - - - - - - - - - - Oxidored_FMN k141_27421_1 1294265.JCM21738_2990 1.4e-80 245.0 COG1734@1|root,COG1734@2|Bacteria,1V4KF@1239|Firmicutes,4HHBC@91061|Bacilli,1ZQQT@1386|Bacillus 91061|Bacilli T Prokaryotic dksA/traR C4-type zinc finger - - - - - - - - - - - - zf-dskA_traR k141_21552_1 1196031.ALEG01000028_gene4315 9.34e-114 337.0 COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,4HAPA@91061|Bacilli,1ZBBG@1386|Bacillus 91061|Bacilli C alcohol dehydrogenase adhB - 1.1.1.1,1.1.1.202 ko:K00001,ko:K00086 ko00010,ko00071,ko00350,ko00561,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00561,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R02377,R03119,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - Fe-ADH k141_153_1 1117647.M5M_16815 8.64e-122 378.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MWS3@1224|Proteobacteria,1RPG6@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Outer membrane receptor proteins mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec k141_2505_1 631362.Thi970DRAFT_04690 9.71e-101 301.0 COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,1RNCK@1236|Gammaproteobacteria,1WW0A@135613|Chromatiales 135613|Chromatiales Q Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - - - - - - - - - - DctP k141_3699_1 1279017.AQYJ01000019_gene1520 6.8e-115 342.0 COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,1RQJ9@1236|Gammaproteobacteria,4656M@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K03585 ko01501,ko01503,map01501,map01503 M00646,M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,8.A.1.6 - - HlyD_D23 k141_1244_1 1294265.JCM21738_2954 3.06e-156 452.0 COG0367@1|root,COG0367@2|Bacteria,1TRPB@1239|Firmicutes,4HAIP@91061|Bacilli,1ZAPW@1386|Bacillus 91061|Bacilli E Asparagine synthase asnB - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 k141_25051_1 218284.CCDN010000001_gene1610 4.07e-98 294.0 COG1680@1|root,COG1680@2|Bacteria,1VSBT@1239|Firmicutes,4HV12@91061|Bacilli,1ZIC9@1386|Bacillus 91061|Bacilli V Beta-lactamase adp3 - 3.4.16.4 ko:K01286 - - - - ko00000,ko01000 - - - Beta-lactamase k141_29812_1 218284.CCDN010000002_gene2617 4.53e-55 179.0 COG1595@1|root,COG1595@2|Bacteria,1V9ZH@1239|Firmicutes,4HGNB@91061|Bacilli,1ZGEX@1386|Bacillus 91061|Bacilli K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_31039_1 218284.CCDN010000005_gene3244 1.39e-114 340.0 COG0004@1|root,COG0004@2|Bacteria,1TQYG@1239|Firmicutes,4HBGK@91061|Bacilli,1ZB5S@1386|Bacillus 91061|Bacilli P Ammonium transporter amtB - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - Ammonium_transp k141_15604_1 1117647.M5M_00805 7.26e-10 57.8 COG3630@1|root,COG3630@2|Bacteria,1QJBU@1224|Proteobacteria,1THAJ@1236|Gammaproteobacteria,1JBFP@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C oxaloacetate decarboxylase gamma chain oadG - 4.1.1.3 ko:K01573 ko00620,ko01100,map00620,map01100 - R00217 RC00040 ko00000,ko00001,ko01000,ko02000 3.B.1.1.1 - - OAD_gamma k141_11984_1 42565.FP66_13725 5.57e-85 262.0 COG2031@1|root,COG2031@2|Bacteria,1MV5A@1224|Proteobacteria,1RMTZ@1236|Gammaproteobacteria,1XIXY@135619|Oceanospirillales 135619|Oceanospirillales I fatty acid transporter - - - ko:K02106 ko02020,map02020 - - - ko00000,ko00001 2.A.73.1 - - SCFA_trans k141_11984_2 768066.HELO_3987 1.13e-20 89.7 COG2031@1|root,COG2031@2|Bacteria,1MV5A@1224|Proteobacteria,1RMTZ@1236|Gammaproteobacteria,1XIXY@135619|Oceanospirillales 135619|Oceanospirillales I fatty acid transporter - - - ko:K02106 ko02020,map02020 - - - ko00000,ko00001 2.A.73.1 - - SCFA_trans k141_155_1 218284.CCDN010000006_gene3530 1.33e-66 214.0 2DH6Y@1|root,2ZYKQ@2|Bacteria,1V3RR@1239|Firmicutes,4HHKE@91061|Bacilli,1ZBHI@1386|Bacillus 91061|Bacilli S Spore germination B3/ GerAC like, C-terminal - - - ko:K06308 - - - - ko00000 - - - Spore_GerAC k141_1245_1 42565.FP66_01450 1.53e-33 122.0 COG1179@1|root,COG1179@2|Bacteria,1MWXR@1224|Proteobacteria,1RMT3@1236|Gammaproteobacteria,1XHB5@135619|Oceanospirillales 135619|Oceanospirillales H UBA THIF-type NAD FAD binding - - - ko:K22132 - - - - ko00000,ko03016 - - - ThiF k141_1245_2 42565.FP66_01455 4.74e-49 155.0 COG4728@1|root,COG4728@2|Bacteria,1N6NP@1224|Proteobacteria,1SCKQ@1236|Gammaproteobacteria,1XM5W@135619|Oceanospirillales 135619|Oceanospirillales S protein conserved in bacteria - - - - - - - - - - - - DUF1653 k141_29813_1 1461580.CCAS010000014_gene1818 2.76e-79 246.0 COG0463@1|root,COG0463@2|Bacteria,1TPR3@1239|Firmicutes,4HC2Z@91061|Bacilli,1ZD2D@1386|Bacillus 91061|Bacilli M COG0463 Glycosyltransferases involved in cell wall biogenesis ykoT - - - - - - - - - - - Glycos_transf_2 k141_6082_1 292459.STH2797 3.94e-24 103.0 COG2267@1|root,COG2267@2|Bacteria,1UZ5S@1239|Firmicutes,25CEG@186801|Clostridia 186801|Clostridia I PFAM Alpha Beta hydrolase - - - - - - - - - - - - Hydrolase_4 k141_28674_1 192875.XP_004345543.1 8.08e-30 117.0 COG0183@1|root,KOG1391@2759|Eukaryota,39QWG@33154|Opisthokonta 33154|Opisthokonta I negative regulation of mitochondrial membrane permeability involved in apoptotic process ACAA2 GO:0001666,GO:0003674,GO:0003824,GO:0003988,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006066,GO:0006082,GO:0006084,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006635,GO:0006637,GO:0006694,GO:0006695,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006839,GO:0006915,GO:0006950,GO:0006996,GO:0007005,GO:0007006,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008219,GO:0008610,GO:0008637,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009150,GO:0009259,GO:0009628,GO:0009966,GO:0009968,GO:0009987,GO:0010639,GO:0010646,GO:0010648,GO:0010821,GO:0010823,GO:0010941,GO:0012501,GO:0016042,GO:0016043,GO:0016054,GO:0016125,GO:0016126,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019637,GO:0019693,GO:0019752,GO:0023051,GO:0023057,GO:0030258,GO:0031974,GO:0032787,GO:0032879,GO:0033043,GO:0033554,GO:0033865,GO:0033875,GO:0034032,GO:0034440,GO:0034641,GO:0035383,GO:0035795,GO:0036293,GO:0036294,GO:0042221,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046165,GO:0046395,GO:0046483,GO:0046902,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050896,GO:0051049,GO:0051051,GO:0051128,GO:0051129,GO:0051179,GO:0051186,GO:0051234,GO:0051716,GO:0055086,GO:0055114,GO:0060548,GO:0061024,GO:0065007,GO:0065008,GO:0070013,GO:0070482,GO:0070887,GO:0071453,GO:0071456,GO:0071704,GO:0071840,GO:0072329,GO:0072521,GO:0090559,GO:1901028,GO:1901029,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901575,GO:1901576,GO:1901615,GO:1901617,GO:1902108,GO:1902109,GO:1902652,GO:1902653,GO:1905709,GO:2001233,GO:2001234 2.3.1.16,2.3.1.254 ko:K07508,ko:K17972 ko00062,ko00071,ko00280,ko01100,ko01110,ko01130,ko01212,map00062,map00071,map00280,map01100,map01110,map01130,map01212 M00085,M00087 R00391,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747 RC00004,RC00326,RC00405,RC01702 ko00000,ko00001,ko00002,ko01000,ko03029 - - - Thiolase_C,Thiolase_N k141_11985_1 218284.CCDN010000001_gene1357 1.34e-102 316.0 COG0514@1|root,COG0514@2|Bacteria,1TPN5@1239|Firmicutes,4H9QP@91061|Bacilli,1ZC4U@1386|Bacillus 91061|Bacilli L DNA helicase recQ GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009378,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.6.4.12 ko:K03654 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind k141_2529_1 218284.CCDN010000001_gene1923 4.52e-126 371.0 COG1749@1|root,COG1749@2|Bacteria,1UHS7@1239|Firmicutes,4IS7Y@91061|Bacilli,1ZS24@1386|Bacillus 91061|Bacilli N flagellar flgE - - ko:K02390 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FlaE,Flg_bb_rod,Flg_bbr_C k141_15623_1 218284.CCDN010000001_gene1672 1.6e-105 309.0 COG0546@1|root,COG0546@2|Bacteria,1V4W6@1239|Firmicutes,4HGEW@91061|Bacilli,1ZQ6Z@1386|Bacillus 91061|Bacilli S haloacid dehalogenase-like hydrolase - - 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 - R01334 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 k141_20305_1 1116375.VEJY3_21656 8.62e-09 55.1 COG0656@1|root,COG0656@2|Bacteria,1MWFS@1224|Proteobacteria,1RRAV@1236|Gammaproteobacteria,1XYG2@135623|Vibrionales 135623|Vibrionales S Aldo/keto reductase family - - - - - - - - - - - - Aldo_ket_red k141_20305_2 1116375.VEJY3_21501 5.28e-219 609.0 COG2220@1|root,COG2220@2|Bacteria,1MV20@1224|Proteobacteria,1RN4Z@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Zn-dependent hydrolases of the beta-lactamase fold - - - - - - - - - - - - Lactamase_B_2 k141_20305_3 1348635.BBJY01000006_gene499 7.02e-137 395.0 COG1979@1|root,COG1979@2|Bacteria,1QUBJ@1224|Proteobacteria,1RP7C@1236|Gammaproteobacteria,1XZTQ@135623|Vibrionales 135623|Vibrionales C Iron-containing alcohol dehydrogenase - - - - - - - - - - - - Fe-ADH k141_22736_1 218284.CCDN010000002_gene2881 2.01e-151 429.0 COG1404@1|root,COG1404@2|Bacteria,1V3SC@1239|Firmicutes,4HFE4@91061|Bacilli,1ZF22@1386|Bacillus 91061|Bacilli O Domain of unknown function (DUF4397) - - - - - - - - - - - - DUF4397,Gram_pos_anchor k141_6121_1 1453501.JELR01000001_gene3112 2.82e-92 283.0 COG0174@1|root,COG0174@2|Bacteria,1MU6V@1224|Proteobacteria,1RPNZ@1236|Gammaproteobacteria,46AV5@72275|Alteromonadaceae 1236|Gammaproteobacteria E Glutamine synthetase, catalytic domain - - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C k141_26318_1 1174504.AJTN02000211_gene3639 7.65e-81 247.0 COG0428@1|root,COG0428@2|Bacteria,1TP7J@1239|Firmicutes,4HB3R@91061|Bacilli,1ZB31@1386|Bacillus 91061|Bacilli P Mediates zinc uptake. May also transport other divalent cations zupT - - ko:K07238 - - - - ko00000,ko02000 2.A.5.5 - - Zip k141_26318_2 1231057.AMGD01000040_gene782 6.22e-05 46.6 COG2324@1|root,COG2324@2|Bacteria,1V4BB@1239|Firmicutes,4HI6A@91061|Bacilli,26EXP@186818|Planococcaceae 91061|Bacilli S Carotenoid biosynthesis protein - - - - - - - - - - - - Caroten_synth k141_187_1 1042377.AFPJ01000005_gene2452 3.43e-213 591.0 COG0435@1|root,COG0435@2|Bacteria,1MV50@1224|Proteobacteria,1RMTI@1236|Gammaproteobacteria,4651K@72275|Alteromonadaceae 1236|Gammaproteobacteria O Glutathione S-transferase yqjG - 1.8.5.7 ko:K07393 - - - - ko00000,ko01000 - - - GST_C_2,GST_N_2 k141_187_3 1415780.JPOG01000001_gene377 3.97e-80 239.0 COG0432@1|root,COG0432@2|Bacteria,1RA5G@1224|Proteobacteria,1S3N1@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Uncharacterised protein family UPF0047 - - - - - - - - - - - - UPF0047 k141_187_4 1453501.JELR01000002_gene1161 3.61e-87 262.0 COG0625@1|root,COG0625@2|Bacteria,1MY47@1224|Proteobacteria,1RRI3@1236|Gammaproteobacteria,467CI@72275|Alteromonadaceae 1236|Gammaproteobacteria O Glutathione S-transferase, C-terminal domain - - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C,GST_C_2,GST_C_3,GST_N,GST_N_2,GST_N_3 k141_187_5 1279017.AQYJ01000027_gene1846 8.27e-165 473.0 COG0477@1|root,COG2814@2|Bacteria,1MW19@1224|Proteobacteria,1RMSZ@1236|Gammaproteobacteria,464E9@72275|Alteromonadaceae 1236|Gammaproteobacteria EGP COG0477 Permeases of the major facilitator superfamily - - - ko:K07552 - - - - ko00000,ko02000 2.A.1.2 - - MFS_1 k141_21574_1 1116375.VEJY3_17371 1.57e-121 353.0 COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,1RMR8@1236|Gammaproteobacteria,1XSH2@135623|Vibrionales 135623|Vibrionales P Cation efflux family - - - - - - - - - - - - Cation_efflux k141_21574_2 1116375.VEJY3_17366 9.11e-179 500.0 COG4667@1|root,COG4667@2|Bacteria,1PV7M@1224|Proteobacteria,1RRPR@1236|Gammaproteobacteria,1XTZD@135623|Vibrionales 135623|Vibrionales S esterase of the alpha-beta hydrolase superfamily - - - - - - - - - - - - Patatin k141_6122_1 1168065.DOK_05063 7.86e-48 167.0 COG1538@1|root,COG1538@2|Bacteria,1NEZC@1224|Proteobacteria,1RPC5@1236|Gammaproteobacteria,1J8C3@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria MU COG1538 Outer membrane protein czcC - - ko:K15725 - - - - ko00000,ko02000 1.B.17.2.2 - - OEP k141_9632_2 1294265.JCM21738_2070 2.93e-42 150.0 COG0553@1|root,COG0553@2|Bacteria,1TQ5E@1239|Firmicutes,4H9WB@91061|Bacilli,1ZAR5@1386|Bacillus 91061|Bacilli L COG0553 Superfamily II DNA RNA helicases, SNF2 family yqhH - - - - - - - - - - - Helicase_C,SNF2_N k141_13244_1 1279017.AQYJ01000028_gene2347 1.39e-51 175.0 28I1X@1|root,2Z86C@2|Bacteria,1PPMS@1224|Proteobacteria,1RV76@1236|Gammaproteobacteria,465Y1@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_28703_1 210007.SMU_1423 2.34e-19 90.5 COG1071@1|root,COG1071@2|Bacteria,1TQDG@1239|Firmicutes,4HBEA@91061|Bacilli 91061|Bacilli C Dehydrogenase E1 component acoA - 1.2.4.1 ko:K00161,ko:K21416 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh k141_2530_1 218284.CCDN010000007_gene3964 5.76e-98 293.0 COG1879@1|root,COG1879@2|Bacteria,1TSUI@1239|Firmicutes,4HBMV@91061|Bacilli,1ZC6R@1386|Bacillus 91061|Bacilli G Periplasmic binding protein domain rbsB5 - - ko:K02058 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - Peripla_BP_4 k141_29831_1 218284.CCDN010000005_gene3453 5.42e-131 373.0 COG5018@1|root,COG5018@2|Bacteria,1TT8A@1239|Firmicutes,4HFEZ@91061|Bacilli,1ZBWS@1386|Bacillus 91061|Bacilli L Inhibitor of the KinA pathway kapD - - ko:K06348 - - - - ko00000 - - - RNase_T k141_27440_1 1042377.AFPJ01000032_gene2777 7.67e-84 258.0 COG1808@1|root,COG1808@2|Bacteria,1NMS3@1224|Proteobacteria,1RRTC@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Domain of unknown function (DUF389) - - - - - - - - - - - - DUF389 k141_27440_2 1453501.JELR01000002_gene1438 2.02e-36 125.0 COG0346@1|root,COG0346@2|Bacteria,1RH79@1224|Proteobacteria,1S9UN@1236|Gammaproteobacteria 1236|Gammaproteobacteria E glyoxalase bleomycin resistance protein dioxygenase - - - - - - - - - - - - Glyoxalase k141_12011_1 1453501.JELR01000002_gene460 1.82e-200 563.0 COG3182@1|root,COG3182@2|Bacteria,1MW2S@1224|Proteobacteria,1RQYY@1236|Gammaproteobacteria,46636@72275|Alteromonadaceae 1236|Gammaproteobacteria S PepSY-associated TM region - - - - - - - - - - - - PepSY_TM k141_188_1 218284.CCDN010000001_gene740 9.76e-87 259.0 COG0274@1|root,COG0274@2|Bacteria,1TPAJ@1239|Firmicutes,4HAAJ@91061|Bacilli,1ZCZ6@1386|Bacillus 91061|Bacilli F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate deoC - 4.1.2.4 ko:K01619 ko00030,map00030 - R01066 RC00436,RC00437 ko00000,ko00001,ko01000 - - - DeoC k141_188_2 1307436.PBF_14454 6.73e-06 48.1 COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,4HA1G@91061|Bacilli,1ZASC@1386|Bacillus 91061|Bacilli G COG0366 Glycosidases malL - 3.2.1.10 ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00801,R01718,R01791,R06199 RC00028,RC00059,RC00077,RC00451 ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,DUF3459,Malt_amylase_C k141_23875_1 866895.HBHAL_1566 2.98e-111 331.0 COG2866@1|root,COG2866@2|Bacteria,1V09S@1239|Firmicutes,4HBF2@91061|Bacilli,3NFXX@45667|Halobacillus 91061|Bacilli E Protein of unknown function (DUF2817) - - - - - - - - - - - - DUF2817 k141_3726_1 1042377.AFPJ01000028_gene2248 1.36e-48 157.0 COG1846@1|root,COG1846@2|Bacteria,1R0KA@1224|Proteobacteria,1T4J9@1236|Gammaproteobacteria,46932@72275|Alteromonadaceae 1236|Gammaproteobacteria K Winged helix DNA-binding domain - - - - - - - - - - - - HTH_34 k141_29832_1 218284.CCDN010000001_gene716 4.32e-17 77.4 COG1057@1|root,COG1057@2|Bacteria,1V3SK@1239|Firmicutes,4HGXK@91061|Bacilli,1ZFIV@1386|Bacillus 91061|Bacilli H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) nadD GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 ko:K00969 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like k141_29832_2 345219.Bcoa_2744 2.58e-47 153.0 COG1534@1|root,COG1534@2|Bacteria,1VEGM@1239|Firmicutes,4HKC7@91061|Bacilli,1ZH83@1386|Bacillus 91061|Bacilli J RNA-binding protein containing KH domain, possibly ribosomal protein yhbY - - ko:K07574 - - - - ko00000,ko03009 - - - CRS1_YhbY k141_10798_1 1294265.JCM21738_670 1.85e-265 731.0 COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,4H9Q8@91061|Bacilli,1ZBRE@1386|Bacillus 91061|Bacilli D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase tig GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K03545 - - - - ko00000 - - - FKBP_C,Trigger_C,Trigger_N k141_10798_2 1294265.JCM21738_671 3.38e-75 227.0 COG4783@1|root,COG4783@2|Bacteria,1UHTK@1239|Firmicutes,4HHIW@91061|Bacilli,1ZS3G@1386|Bacillus 91061|Bacilli S chaperone-mediated protein folding - - - - - - - - - - - - TPR_19 k141_20306_1 42565.FP66_07625 2.14e-103 324.0 COG1025@1|root,COG1025@2|Bacteria,1QTVC@1224|Proteobacteria,1T1IG@1236|Gammaproteobacteria,1XI12@135619|Oceanospirillales 135619|Oceanospirillales O Belongs to the peptidase M16 family - - - - - - - - - - - - Peptidase_M16,Peptidase_M16_C,Peptidase_M16_M k141_14428_1 859657.RPSI07_mp1661 9.39e-30 118.0 COG0837@1|root,COG0837@2|Bacteria,1MVFI@1224|Proteobacteria,2VH5F@28216|Betaproteobacteria,1K3IA@119060|Burkholderiaceae 28216|Betaproteobacteria F belongs to the bacterial glucokinase family glk - 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Glucokinase,HTH_6,SIS k141_15625_1 218284.CCDN010000004_gene3083 6.54e-137 389.0 COG0655@1|root,COG0655@2|Bacteria,1TSY9@1239|Firmicutes,4H9MQ@91061|Bacilli,1ZBKC@1386|Bacillus 91061|Bacilli S Belongs to the WrbA family wrbA - 1.6.5.2 ko:K03809 ko00130,ko01110,map00130,map01110 - R02964,R03643,R03816 RC00819 ko00000,ko00001,ko01000 - - - FMN_red k141_16767_2 1279017.AQYJ01000022_gene2665 1.36e-118 342.0 COG0632@1|root,COG0632@2|Bacteria,1MWJR@1224|Proteobacteria,1RMET@1236|Gammaproteobacteria,466RJ@72275|Alteromonadaceae 1236|Gammaproteobacteria L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB ruvA GO:0000217,GO:0000400,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 ko:K03550 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - HHH_5,RuvA_C,RuvA_N k141_35758_2 1042377.AFPJ01000028_gene2195 4.82e-310 848.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,463YY@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains glnG GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K07712 ko02020,map02020 M00497 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat k141_35758_3 1279017.AQYJ01000028_gene2036 2.24e-205 574.0 COG3852@1|root,COG3852@2|Bacteria,1MVN6@1224|Proteobacteria,1RN15@1236|Gammaproteobacteria,46416@72275|Alteromonadaceae 1236|Gammaproteobacteria T Signal transduction histidine kinase, nitrogen specific glnL GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019222,GO:0019538,GO:0023014,GO:0023052,GO:0035556,GO:0036211,GO:0042578,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051716,GO:0065007,GO:0071704,GO:0140096,GO:1901564 2.7.13.3 ko:K07708 ko02020,map02020 M00497 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS,PAS_4 k141_35758_4 1279017.AQYJ01000028_gene2035 4.3e-59 194.0 2AFX8@1|root,3160N@2|Bacteria,1QE3Z@1224|Proteobacteria,1TAFT@1236|Gammaproteobacteria,4691A@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF4124) - - - - - - - - - - - - DUF4124 k141_189_1 1385513.N780_17640 1.59e-123 379.0 COG2273@1|root,COG2273@2|Bacteria,1TR5U@1239|Firmicutes,4HB9D@91061|Bacilli,2YB4A@289201|Pontibacillus 91061|Bacilli G PFAM glycoside hydrolase family 16 - - - - - - - - - - - - CBM_4_9,Glyco_hydro_16,SLH k141_5104_1 981383.AEWH01000043_gene1572 6.98e-40 144.0 COG0596@1|root,COG0596@2|Bacteria,1V9D7@1239|Firmicutes 1239|Firmicutes S Alpha beta hydrolase - - - - - - - - - - - - Abhydrolase_1 k141_8684_1 218284.CCDN010000001_gene551 4.56e-146 434.0 COG0072@1|root,COG0072@2|Bacteria,1TP98@1239|Firmicutes,4HAQ9@91061|Bacilli,1ZB8G@1386|Bacillus 91061|Bacilli J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily pheT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - B3_4,B5,FDX-ACB,tRNA_bind k141_9860_1 1453501.JELR01000001_gene1824 2.45e-93 282.0 COG0082@1|root,COG0082@2|Bacteria,1MU98@1224|Proteobacteria,1RMQS@1236|Gammaproteobacteria,46517@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system aroC GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01714 RC00586 ko00000,ko00001,ko00002,ko01000 - - iE2348C_1286.E2348C_2469,iEC55989_1330.EC55989_2573,iECO103_1326.ECO103_2794,iECO111_1330.ECO111_3077,iECO26_1355.ECO26_3317,iECSE_1348.ECSE_2638,iECW_1372.ECW_m2518,iEKO11_1354.EKO11_1436,iSSON_1240.SSON_2387,iUMNK88_1353.UMNK88_2882,iWFL_1372.ECW_m2518 Chorismate_synt k141_9860_2 1042377.AFPJ01000037_gene3008 1.14e-126 365.0 COG3637@1|root,COG3637@2|Bacteria,1R3QN@1224|Proteobacteria,1RY3J@1236|Gammaproteobacteria,467AR@72275|Alteromonadaceae 1236|Gammaproteobacteria M Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - - - - - - - - - - - k141_33628_1 545693.BMQ_3373 2.19e-97 295.0 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4HB97@91061|Bacilli,1ZBGZ@1386|Bacillus 91061|Bacilli C Belongs to the aldehyde dehydrogenase family - - 1.2.1.3 ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_12348_1 1192034.CAP_6065 3.71e-97 313.0 COG1061@1|root,COG3886@1|root,COG1061@2|Bacteria,COG3886@2|Bacteria,1MV9F@1224|Proteobacteria,42NS1@68525|delta/epsilon subdivisions,2WQXY@28221|Deltaproteobacteria,2YWZQ@29|Myxococcales 28221|Deltaproteobacteria KL Domain of unknown function (DUF3427) - - - - - - - - - - - - DUF3427,Helicase_C,PLDc_2,ResIII k141_8685_1 218284.CCDN010000002_gene2864 4.49e-09 56.2 COG1396@1|root,COG1396@2|Bacteria,1VDMN@1239|Firmicutes,4HDVP@91061|Bacilli,1ZS6Z@1386|Bacillus 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - ko:K20480 ko02024,map02024 - - - ko00000,ko00001,ko03000 - - - HTH_3 k141_8685_2 218284.CCDN010000002_gene2863 6.98e-27 99.0 29S9H@1|root,30DE0@2|Bacteria,1UB6N@1239|Firmicutes,4IMJC@91061|Bacilli,1ZKA9@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_448_4 742733.HMPREF9469_05909 3.11e-06 46.6 COG0864@1|root,COG0864@2|Bacteria,1UKIN@1239|Firmicutes,25FY3@186801|Clostridia 186801|Clostridia K Transcriptional regulator - - - - - - - - - - - - - k141_448_5 1540090.A0A0A0RMM3_9CAUD 1.59e-25 105.0 4QAIU@10239|Viruses,4QPDE@28883|Caudovirales,4QI6J@10662|Myoviridae 10662|Myoviridae S sequence-specific DNA binding transcription factor activity - - - - - - - - - - - - - k141_32337_1 1453501.JELR01000002_gene988 3.29e-187 526.0 COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,1RN0B@1236|Gammaproteobacteria,464NP@72275|Alteromonadaceae 1236|Gammaproteobacteria NU COG5008 Tfp pilus assembly protein, ATPase PilU pilU - - ko:K02670 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE k141_32337_2 1517416.IDAT_07405 4.49e-116 340.0 COG0596@1|root,COG0596@2|Bacteria,1N252@1224|Proteobacteria,1SDH5@1236|Gammaproteobacteria,2QGQC@267893|Idiomarinaceae 1236|Gammaproteobacteria S Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 k141_32337_3 1042377.AFPJ01000054_gene1708 5.83e-101 301.0 COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,1RMJJ@1236|Gammaproteobacteria,466SZ@72275|Alteromonadaceae 1236|Gammaproteobacteria KT COG3279 Response regulator of the LytR AlgR family algR - - ko:K08083 ko02020,map02020 M00493 - - ko00000,ko00001,ko00002,ko02022 - - - LytTR,Response_reg k141_32337_4 1279017.AQYJ01000027_gene1625 1.8e-156 453.0 COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,1RQDA@1236|Gammaproteobacteria,4666A@72275|Alteromonadaceae 1236|Gammaproteobacteria T signal transduction protein with a C-terminal ATPase domain algZ - 2.7.13.3 ko:K08082 ko02020,map02020 M00493 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - His_kinase k141_32337_5 1453501.JELR01000002_gene992 7.91e-316 863.0 COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,1RMA3@1236|Gammaproteobacteria,4644I@72275|Alteromonadaceae 1236|Gammaproteobacteria E argininosuccinate lyase argH GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01086 RC00445,RC00447 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ASL_C2,Lyase_1 k141_32337_8 1042377.AFPJ01000054_gene1702 6.93e-256 707.0 COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,1RMI2@1236|Gammaproteobacteria,4641G@72275|Alteromonadaceae 1236|Gammaproteobacteria E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine lysA GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008836,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N,Orn_DAP_Arg_deC k141_32337_9 1279017.AQYJ01000027_gene1630 3.68e-159 450.0 COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,1RMGV@1236|Gammaproteobacteria,464H0@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan dapF - 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 - - - DAP_epimerase k141_32337_10 1453501.JELR01000002_gene997 2.61e-113 332.0 COG3159@1|root,COG3159@2|Bacteria,1R4BP@1224|Proteobacteria,1S9SC@1236|Gammaproteobacteria,467JP@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria yigA - - ko:K09921 - - - - ko00000 - - - DUF484 k141_32337_11 1045855.DSC_02965 1.39e-98 300.0 COG4973@1|root,COG4973@2|Bacteria,1MUJJ@1224|Proteobacteria,1RMJG@1236|Gammaproteobacteria,1X31C@135614|Xanthomonadales 135614|Xanthomonadales L Belongs to the 'phage' integrase family. XerC subfamily xerC - - ko:K03733 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase k141_32337_12 566466.NOR53_2419 3.22e-269 757.0 28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,1RRUM@1236|Gammaproteobacteria,1J8KD@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF3604) - - - - - - - - - - - - DUF3604 k141_33629_1 1123236.KB899384_gene2388 1.33e-105 316.0 COG2610@1|root,COG2610@2|Bacteria,1N2VU@1224|Proteobacteria,1RNCQ@1236|Gammaproteobacteria,465BE@72275|Alteromonadaceae 1236|Gammaproteobacteria EG COG2610 H gluconate symporter and related permeases - - - - - - - - - - - - CitMHS,GntP_permease k141_5106_1 218284.CCDN010000002_gene2771 1.45e-21 86.7 2DFJN@1|root,2ZS4E@2|Bacteria,1W278@1239|Firmicutes,4HZWP@91061|Bacilli,1ZK2E@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3934) - - - - - - - - - - - - DUF3934 k141_5106_2 935837.JAEK01000040_gene3712 1.54e-09 54.7 COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,4HNJC@91061|Bacilli,1ZHSU@1386|Bacillus 91061|Bacilli K Cold shock - - - ko:K03704 - - - - ko00000,ko03000 - - - CSD k141_22986_1 1042377.AFPJ01000007_gene1871 3.2e-66 207.0 COG1136@1|root,COG1136@2|Bacteria,1NCFC@1224|Proteobacteria 1224|Proteobacteria V ABC transporter MA20_22875 - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_14577_1 218284.CCDN010000002_gene2138 7.53e-123 361.0 COG3844@1|root,COG3844@2|Bacteria,1TQ8V@1239|Firmicutes,4HBE8@91061|Bacilli,1ZBCN@1386|Bacillus 91061|Bacilli E Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively kynU GO:0003674,GO:0003824,GO:0016787,GO:0016822,GO:0016823,GO:0030429 3.7.1.3 ko:K01556 ko00380,ko01100,map00380,map01100 M00038 R00987,R02668,R03936 RC00284,RC00415 ko00000,ko00001,ko00002,ko01000 - - - Aminotran_5 k141_12349_1 218284.CCDN010000006_gene3578 7.51e-13 66.6 COG1834@1|root,COG1834@2|Bacteria,1UYBH@1239|Firmicutes,4HDEA@91061|Bacilli,1ZHNP@1386|Bacillus 91061|Bacilli E Amidinotransferase - - - - - - - - - - - - Amidinotransf k141_12349_2 218284.CCDN010000006_gene3579 3.83e-72 228.0 COG1113@1|root,COG1113@2|Bacteria,1TP97@1239|Firmicutes,4H9QX@91061|Bacilli,1ZDGG@1386|Bacillus 91061|Bacilli E COG1113 Gamma-aminobutyrate permease and related permeases ycgH GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03293 - - - - ko00000 2.A.3.1 - - AA_permease k141_6408_1 1294265.JCM21738_4334 7.02e-22 90.5 COG1647@1|root,COG1647@2|Bacteria,1TQ7X@1239|Firmicutes,4HBE6@91061|Bacilli,1ZAVD@1386|Bacillus 91061|Bacilli S Carboxylesterase est GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0008150,GO:0008152,GO:0016020,GO:0016298,GO:0016787,GO:0016788,GO:0044238,GO:0071704 3.1.1.1 ko:K03928 - - - - ko00000,ko01000 - - - Hydrolase_4 k141_6408_2 1131730.BAVI_25130 4.05e-33 115.0 COG1314@1|root,COG1314@2|Bacteria,1VEQR@1239|Firmicutes,4HNKC@91061|Bacilli,1ZHZV@1386|Bacillus 91061|Bacilli U Preprotein translocase subunit SecG secG GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0033036,GO:0034613,GO:0042886,GO:0043952,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944 - ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecG k141_16986_1 1042377.AFPJ01000038_gene1099 2.25e-118 370.0 COG0591@1|root,COG0642@1|root,COG0784@1|root,COG0591@2|Bacteria,COG0784@2|Bacteria,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,1RP2U@1236|Gammaproteobacteria,465DY@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0591 Na proline symporter - - - - - - - - - - - - HATPase_c,HisKA,PAS_7,Response_reg,SSF k141_1487_1 1453501.JELR01000001_gene2683 8.21e-196 548.0 COG1446@1|root,COG1446@2|Bacteria,1MWFC@1224|Proteobacteria,1RNUR@1236|Gammaproteobacteria,465B7@72275|Alteromonadaceae 1236|Gammaproteobacteria E Asparaginase iaaA - 3.4.19.5,3.5.1.1 ko:K01424,ko:K13051 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 - R00485 RC00010,RC02798 ko00000,ko00001,ko01000,ko01002 - - - Asparaginase_2 k141_28901_2 1460640.JCM19046_796 7.76e-05 48.9 2BJPM@1|root,32E17@2|Bacteria,1V7X9@1239|Firmicutes,4HJYW@91061|Bacilli,1ZJDM@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_8686_1 935837.JAEK01000024_gene1022 3.65e-166 471.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,4HAEH@91061|Bacilli,1ZCZK@1386|Bacillus 91061|Bacilli J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis tuf GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K02358 - - - - ko00000,ko03012,ko03029,ko04147 - - iSB619.SA_RS02960 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 k141_2751_1 1294265.JCM21738_2402 1.25e-119 351.0 COG4857@1|root,COG4857@2|Bacteria,1TPHY@1239|Firmicutes,4H9QU@91061|Bacilli,1ZBZS@1386|Bacillus 91061|Bacilli F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate mtnK - 2.7.1.100 ko:K00899 ko00270,ko01100,map00270,map01100 M00034 R04143 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - APH k141_9862_1 1042377.AFPJ01000028_gene2192 1.39e-50 169.0 2C3WA@1|root,2Z8P1@2|Bacteria,1R8VC@1224|Proteobacteria,1S5UD@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_9862_2 1042377.AFPJ01000028_gene2193 8.16e-43 150.0 2C3WA@1|root,2Z8P1@2|Bacteria,1R8VC@1224|Proteobacteria,1S5UD@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_20487_2 1209072.ALBT01000023_gene4094 1.05e-46 174.0 COG1657@1|root,COG2304@1|root,COG3386@1|root,COG1657@2|Bacteria,COG2304@2|Bacteria,COG3386@2|Bacteria,1RFDH@1224|Proteobacteria,1S0SI@1236|Gammaproteobacteria,1FHU5@10|Cellvibrio 1236|Gammaproteobacteria I CarboxypepD_reg-like domain - - - - - - - - - - - - CarboxypepD_reg,DUF1194,Prenyltrans k141_8687_2 218284.CCDN010000007_gene4026 9.69e-40 133.0 COG1396@1|root,COG1396@2|Bacteria,1VAXE@1239|Firmicutes,4HKHB@91061|Bacilli,1ZHZH@1386|Bacillus 91061|Bacilli K transcriptional sinR GO:0008150,GO:0009892,GO:0010468,GO:0010605,GO:0010629,GO:0019222,GO:0048519,GO:0050789,GO:0060255,GO:0065007 - ko:K19449 - - - - ko00000,ko03000 - - - HTH_3,SinI k141_32338_1 545693.BMQ_0878 3.14e-108 318.0 COG0266@1|root,COG0266@2|Bacteria,1TP6F@1239|Firmicutes,4HBIU@91061|Bacilli,1ZCVD@1386|Bacillus 91061|Bacilli L Formamidopyrimidine-DNA glycosylase H2TH domain - - 4.2.99.18 ko:K05522 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Fapy_DNA_glyco,H2TH,zf-FPG_IleRS k141_33662_1 1410624.JNKK01000004_gene400 1.55e-06 52.8 COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,25100@186801|Clostridia,27K9X@186928|unclassified Lachnospiraceae 186801|Clostridia M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein murF - 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 - R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M k141_33662_2 443144.GM21_0505 7.02e-51 174.0 COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,42MCP@68525|delta/epsilon subdivisions,2WJDS@28221|Deltaproteobacteria,43UBH@69541|Desulfuromonadales 28221|Deltaproteobacteria M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan mraY - 2.7.8.13 ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 - R05629,R05630 RC00002,RC02753 ko00000,ko00001,ko01000,ko01011 9.B.146 - iAF987.Gmet_0409 Glycos_transf_4,MraY_sig1 k141_25341_1 1273538.G159_11120 6.89e-60 189.0 COG0590@1|root,COG0590@2|Bacteria,1V733@1239|Firmicutes,4HJ78@91061|Bacilli 91061|Bacilli FJ MafB19-like deaminase - - 3.5.4.33 ko:K11991 - - R10223 RC00477 ko00000,ko01000,ko03016 - - - dCMP_cyt_deam_1 k141_25341_2 265729.GS18_0216035 2.78e-19 82.8 2EA57@1|root,334A4@2|Bacteria,1VHEA@1239|Firmicutes,4HQZU@91061|Bacilli,1ZIXN@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_6425_1 1453501.JELR01000002_gene241 2.35e-197 556.0 COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,1RN3R@1236|Gammaproteobacteria,464NA@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) gltX GO:0003674,GO:0003824,GO:0004812,GO:0004818,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006424,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.17 ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 - - iEC042_1314.EC042_2616 tRNA-synt_1c k141_470_1 218284.CCDN010000001_gene730 1.32e-117 352.0 COG0481@1|root,COG0481@2|Bacteria,1TP0G@1239|Firmicutes,4HASA@91061|Bacilli,1ZC7J@1386|Bacillus 91061|Bacilli M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner lepA - - ko:K03596 ko05134,map05134 - - - ko00000,ko00001 - - - EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C k141_26705_1 1294265.JCM21738_314 1.55e-77 231.0 COG2201@1|root,COG2201@2|Bacteria,1V3IU@1239|Firmicutes,4HGY2@91061|Bacilli,1ZG7Q@1386|Bacillus 91061|Bacilli T response regulator cheY - - ko:K03413 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - Response_reg k141_26705_2 1294265.JCM21738_315 1.79e-55 175.0 COG3190@1|root,COG3190@2|Bacteria 2|Bacteria N flagellar fliZ - - ko:K02418 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - FliO k141_4029_1 198628.Dda3937_01521 9.48e-15 79.3 COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1MWPE@1224|Proteobacteria,1RN8X@1236|Gammaproteobacteria,2JBW3@204037|Dickeya 1236|Gammaproteobacteria J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA sun GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 ko:K03500 - - - - ko00000,ko01000,ko03009 - - - Methyltr_RsmB-F,Methyltr_RsmF_N,NusB k141_32358_1 1196031.ALEG01000006_gene405 1.74e-35 136.0 COG3420@1|root,COG3420@2|Bacteria,1UN63@1239|Firmicutes,4HAZN@91061|Bacilli,1ZE50@1386|Bacillus 91061|Bacilli P Periplasmic copper-binding protein (NosD) nosD - - ko:K07218 - - - - ko00000 - - - NosD k141_7455_1 1294265.JCM21738_4349 2.87e-92 280.0 COG3583@1|root,COG3584@1|root,COG3583@2|Bacteria,COG3584@2|Bacteria,1TTIK@1239|Firmicutes,4HC79@91061|Bacilli,1ZC0Q@1386|Bacillus 91061|Bacilli T protein conserved in bacteria yabE - - - - - - - - - - - 3D,DUF348,G5 k141_15824_1 1191523.MROS_2388 1.08e-57 199.0 COG3250@1|root,COG3250@2|Bacteria 2|Bacteria G beta-galactosidase activity - - 3.1.1.53 ko:K05970 - - - - ko00000,ko01000 - - - Glyco_hydro_2_N,SASA k141_21776_1 218284.CCDN010000002_gene2839 9.06e-120 352.0 COG2377@1|root,COG2377@2|Bacteria,1TSBU@1239|Firmicutes,4HAYA@91061|Bacilli,1ZEPB@1386|Bacillus 91061|Bacilli O Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling anmK - 2.7.1.170 ko:K09001 - - - - ko00000,ko01000 - - - AnmK k141_12365_2 1279017.AQYJ01000028_gene2320 7.41e-68 228.0 COG0709@1|root,COG1252@1|root,COG0709@2|Bacteria,COG1252@2|Bacteria,1MWFG@1224|Proteobacteria,1RQ5Q@1236|Gammaproteobacteria,465WT@72275|Alteromonadaceae 1236|Gammaproteobacteria CE Belongs to the selenophosphate synthase 1 family. Class I subfamily - - 2.7.9.3 ko:K01008 ko00450,ko01100,map00450,map01100 - R03595 RC00002,RC02878 ko00000,ko00001,ko01000,ko03016 - - - AIRS,AIRS_C,Pyr_redox_2 k141_33663_1 218284.CCDN010000002_gene2414 8.91e-71 220.0 2DBJ5@1|root,2Z9IG@2|Bacteria,1VIXW@1239|Firmicutes,4HPR1@91061|Bacilli,1ZB1A@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_34813_1 218284.CCDN010000004_gene3100 1.44e-107 314.0 COG2364@1|root,COG2364@2|Bacteria,1V47R@1239|Firmicutes,4HGYQ@91061|Bacilli,1ZG36@1386|Bacillus 91061|Bacilli S membrane - - - ko:K07149 - - - - ko00000 - - - YitT_membrane k141_20513_1 1219076.N646_2427 1.29e-170 481.0 COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,1RPTA@1236|Gammaproteobacteria,1XTE0@135623|Vibrionales 135623|Vibrionales M COG0451 Nucleoside-diphosphate-sugar epimerases - - 5.1.3.6 ko:K08679 ko00520,ko01100,map00520,map01100 - R01385 RC00289 ko00000,ko00001,ko01000 - - - Epimerase,GDP_Man_Dehyd k141_20513_2 1280001.BAOA01000021_gene730 3.56e-93 281.0 COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,1RMVW@1236|Gammaproteobacteria,1XTZN@135623|Vibrionales 135623|Vibrionales C Belongs to the UDP-glucose GDP-mannose dehydrogenase family ugd - 1.1.1.22 ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 M00014,M00129,M00361,M00362 R00286 RC00291 ko00000,ko00001,ko00002,ko01000 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N k141_13531_1 218284.CCDN010000001_gene1094 1.72e-111 329.0 COG0539@1|root,COG0539@2|Bacteria,1TQ9N@1239|Firmicutes,4H9PX@91061|Bacilli,1ZARR@1386|Bacillus 91061|Bacilli J Ribosomal protein S1 rpsA - - ko:K02945 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - S1 k141_26706_1 220664.PFL_4949 2.55e-66 214.0 COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RNN0@1236|Gammaproteobacteria,1YN5B@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria E DegT/DnrJ/EryC1/StrS aminotransferase family ybdL - 2.6.1.88 ko:K14287 - - R08618 RC00006,RC00025 ko00000,ko01000,ko01007 - - - Aminotran_1_2 k141_17005_2 1461580.CCAS010000005_gene768 5.22e-16 70.9 2DKK1@1|root,309RW@2|Bacteria,1U5JZ@1239|Firmicutes,4IFAR@91061|Bacilli,1ZK2R@1386|Bacillus 91061|Bacilli S YqzL-like protein - - - - - - - - - - - - YqzL k141_31274_2 1121090.KB894717_gene3247 5.8e-90 270.0 COG3764@1|root,COG3764@2|Bacteria,1V1RS@1239|Firmicutes,4HFWK@91061|Bacilli,1ZFRS@1386|Bacillus 91061|Bacilli M COG3764 Sortase (surface protein transpeptidase) - - 3.4.22.70 ko:K07284 - - - - ko00000,ko01000,ko01002,ko01011 - - - Sortase k141_29989_1 218284.CCDN010000001_gene1817 2.13e-112 335.0 COG0044@1|root,COG0044@2|Bacteria,1TP8C@1239|Firmicutes,4H9N0@91061|Bacilli,1ZQ9M@1386|Bacillus 91061|Bacilli F Amidohydrolase family hydA - 3.5.2.2 ko:K01464 ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100 M00046 R02269,R03055,R08227 RC00632,RC00680 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Amidohydro_1 k141_29989_2 218284.CCDN010000001_gene1816 6.38e-175 499.0 COG1953@1|root,COG1953@2|Bacteria,1TS5W@1239|Firmicutes,4HAIM@91061|Bacilli,1ZDNH@1386|Bacillus 91061|Bacilli FH COG1953 Cytosine uracil thiamine allantoin permeases pucI - - ko:K03457 - - - - ko00000 2.A.39 - - Transp_cyt_pur k141_8723_1 218284.CCDN010000005_gene3167 1.51e-37 147.0 COG4717@1|root,COG4717@2|Bacteria,1TQP3@1239|Firmicutes,4HBCA@91061|Bacilli,1ZDHB@1386|Bacillus 91061|Bacilli L AAA domain yhaN - - - - - - - - - - - AAA_27 k141_12366_1 42565.FP66_11640 1.23e-13 67.8 COG0517@1|root,COG0517@2|Bacteria,1RJTX@1224|Proteobacteria,1S6K2@1236|Gammaproteobacteria,1XJHR@135619|Oceanospirillales 135619|Oceanospirillales S CBS domain containing protein - - - - - - - - - - - - CBS k141_12366_2 42565.FP66_11635 9.03e-56 187.0 COG0069@1|root,COG0069@2|Bacteria,1MU7B@1224|Proteobacteria,1RP1C@1236|Gammaproteobacteria,1XH9N@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the glutamate synthase family - - - - - - - - - - - - Glu_synthase k141_37140_1 1161401.ASJA01000016_gene1323 5.76e-17 80.5 COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,2TQKQ@28211|Alphaproteobacteria,43W4P@69657|Hyphomonadaceae 28211|Alphaproteobacteria E Belongs to the GMC oxidoreductase family betA - 1.1.99.1 ko:K00108 ko00260,ko01100,map00260,map01100 M00555 R01025 RC00087 ko00000,ko00001,ko00002,ko01000 - - - GMC_oxred_C,GMC_oxred_N k141_14596_1 1294265.JCM21738_3615 2.69e-65 202.0 2AD1W@1|root,312Q2@2|Bacteria,1V37T@1239|Firmicutes,4HG4D@91061|Bacilli,1ZF11@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_13533_1 218284.CCDN010000001_gene132 6.52e-111 348.0 COG1038@1|root,COG1038@2|Bacteria,1UHP9@1239|Firmicutes,4IS56@91061|Bacilli,1ZC4R@1386|Bacillus 91061|Bacilli C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second pyc - 6.4.1.1 ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 M00173 R00344 RC00040,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,HMGL-like,PYC_OADA k141_24114_1 997296.PB1_13829 5.15e-15 75.1 28MSG@1|root,2ZB0U@2|Bacteria,1TT1H@1239|Firmicutes,4HBNQ@91061|Bacilli,1ZCHW@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2515) yppC - - - - - - - - - - - DUF2515 k141_24114_2 218284.CCDN010000001_gene1151 2.45e-120 346.0 COG3331@1|root,COG3331@2|Bacteria,1V3S4@1239|Firmicutes,4HGZ7@91061|Bacilli,1ZCV9@1386|Bacillus 91061|Bacilli L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation recU GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - ko:K03700 - - - - ko00000,ko03400 - - - RecU k141_471_1 1382358.JHVN01000006_gene137 8.3e-87 261.0 COG0370@1|root,COG0370@2|Bacteria,1TRZF@1239|Firmicutes,4HDXP@91061|Bacilli,21WAJ@150247|Anoxybacillus 91061|Bacilli P Signal recognition particle receptor beta subunit - - - - - - - - - - - - FeoB_N k141_11086_1 218284.CCDN010000005_gene3346 3.23e-74 233.0 COG2199@1|root,COG3706@2|Bacteria,1V2QN@1239|Firmicutes,4HFY9@91061|Bacilli,1ZCMZ@1386|Bacillus 91061|Bacilli T diguanylate cyclase - - - - - - - - - - - - 5TM-5TMR_LYT,GGDEF,PAS_3 k141_33666_1 218284.CCDN010000001_gene1713 1.29e-75 231.0 2C009@1|root,32UHI@2|Bacteria,1V4P1@1239|Firmicutes,4HH50@91061|Bacilli,1ZE0W@1386|Bacillus 91061|Bacilli S FBP C-terminal treble-clef zinc-finger - - - - - - - - - - - - EF-G-binding_N,FBP_C k141_13534_1 218284.CCDN010000001_gene1076 4.43e-86 255.0 2EENU@1|root,338GN@2|Bacteria,1VK1A@1239|Firmicutes,4HNX3@91061|Bacilli,1ZC57@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2663) ypbF - - - - - - - - - - - DUF2663 k141_29990_1 265729.GS18_0214525 3.01e-90 275.0 COG1294@1|root,COG1294@2|Bacteria,1TPYX@1239|Firmicutes,4HA9T@91061|Bacilli,1ZCH6@1386|Bacillus 91061|Bacilli C COG1294 Cytochrome bd-type quinol oxidase, subunit 2 ythB - 1.10.3.14 ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - Cyt_bd_oxida_II k141_12368_1 218284.CCDN010000008_gene4214 8.99e-54 189.0 COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,4HA1S@91061|Bacilli,1ZAYY@1386|Bacillus 91061|Bacilli D Belongs to the FtsK SpoIIIE SftA family sftA - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_SpoIIIE,Ftsk_gamma k141_8724_1 1286106.MPL1_00457 3.39e-30 130.0 COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,1RPV3@1236|Gammaproteobacteria,461X9@72273|Thiotrichales 72273|Thiotrichales NU Type IV fimbrial biogenesis protein PilY1 - - - ko:K02674 - - - - ko00000,ko02035,ko02044 - - - Neisseria_PilC k141_472_1 479434.Sthe_0156 7.93e-48 169.0 COG3850@1|root,COG3850@2|Bacteria,2GBH4@200795|Chloroflexi,27XF0@189775|Thermomicrobia 189775|Thermomicrobia T Histidine kinase - - - - - - - - - - - - GAF_2,HATPase_c,HisKA_3 k141_34817_1 1033802.SSPSH_000622 1.89e-20 92.4 COG3087@1|root,COG3087@2|Bacteria,1MYFG@1224|Proteobacteria,1SD3J@1236|Gammaproteobacteria 1236|Gammaproteobacteria D Cell division protein ftsN - - ko:K03591 - - - - ko00000,ko03036 - - - SPOR k141_11087_1 218284.CCDN010000001_gene734 2.71e-131 389.0 COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,4HA9S@91061|Bacilli,1ZAZ2@1386|Bacillus 91061|Bacilli O Heat shock 70 kDa protein dnaK GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0030246,GO:0030247,GO:0044464,GO:0051704,GO:0098630,GO:0098743,GO:2001065 - ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 - - HSP70 k141_27608_1 218284.CCDN010000001_gene563 5.14e-156 442.0 COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,4HAE2@91061|Bacilli,1ZBCR@1386|Bacillus 91061|Bacilli C Electron transfer flavoprotein etfA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 - ko:K03522 - - - - ko00000,ko04147 - - - ETF,ETF_alpha k141_28919_1 1442599.JAAN01000052_gene2639 4.76e-96 310.0 COG4733@1|root,COG4733@2|Bacteria,1MXB4@1224|Proteobacteria,1RRUV@1236|Gammaproteobacteria,1X3BW@135614|Xanthomonadales 135614|Xanthomonadales S Putative phage tail protein - - - - - - - - - - - - Phage-tail_3 k141_25342_1 653045.Strvi_5234 2.67e-165 490.0 COG1926@1|root,COG2312@1|root,COG1926@2|Bacteria,COG2312@2|Bacteria,2GJUU@201174|Actinobacteria 201174|Actinobacteria Q phosphoribosyltransferase - GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - ko:K07100 - - - - ko00000 - - - Erythro_esteras,Pribosyltran k141_4030_1 218284.CCDN010000008_gene4242 2.54e-92 280.0 COG3266@1|root,COG3266@2|Bacteria,1UYHI@1239|Firmicutes,4HFF7@91061|Bacilli,1ZE70@1386|Bacillus 91061|Bacilli S domain, Protein - - - - - - - - - - - - - k141_9897_1 1279017.AQYJ01000021_gene2852 7.03e-191 543.0 COG0738@1|root,COG0738@2|Bacteria,1MXDC@1224|Proteobacteria,1RQX9@1236|Gammaproteobacteria,463ZE@72275|Alteromonadaceae 1236|Gammaproteobacteria G glucose galactose transporter gluP - - ko:K02429 - - - - ko00000,ko02000 2.A.1.7 - - MFS_1 k141_10137_2 1122134.KB893651_gene1897 1.41e-160 464.0 COG1914@1|root,COG1914@2|Bacteria,1MW6X@1224|Proteobacteria,1RNA2@1236|Gammaproteobacteria,1XMVS@135619|Oceanospirillales 135619|Oceanospirillales P H( )-stimulated, divalent metal cation uptake system mntH - - ko:K03322 - - - - ko00000,ko02000 2.A.55.2.6,2.A.55.3 - - Nramp k141_17122_1 1007105.PT7_1851 2.58e-78 254.0 COG2015@1|root,COG2015@2|Bacteria,1MU82@1224|Proteobacteria,2VJ5N@28216|Betaproteobacteria,3T1HP@506|Alcaligenaceae 28216|Betaproteobacteria Q Alkyl sulfatase dimerisation - - - - - - - - - - - - Alkyl_sulf_C,Alkyl_sulf_dimr,Lactamase_B k141_29022_1 1453501.JELR01000001_gene2160 2.92e-60 199.0 COG3203@1|root,COG3203@2|Bacteria 2|Bacteria M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - - - - - - - - - - Porin_4 k141_14713_1 1453501.JELR01000005_gene1698 2.61e-132 381.0 COG4989@1|root,COG4989@2|Bacteria,1MY3G@1224|Proteobacteria,1RRIC@1236|Gammaproteobacteria,4648X@72275|Alteromonadaceae 1236|Gammaproteobacteria S Oxidoreductase ydhF GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - - - - - - - - - - Aldo_ket_red k141_37289_1 1453501.JELR01000002_gene1382 0.0 1200.0 COG0591@1|root,COG0642@1|root,COG0784@1|root,COG0591@2|Bacteria,COG0784@2|Bacteria,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,1RP2U@1236|Gammaproteobacteria,465DY@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0591 Na proline symporter - - - - - - - - - - - - HATPase_c,HisKA,PAS_7,Response_reg,SSF k141_15938_2 1279017.AQYJ01000022_gene2564 2.12e-285 786.0 COG2234@1|root,COG2234@2|Bacteria,1NE83@1224|Proteobacteria,1RN9P@1236|Gammaproteobacteria,465X9@72275|Alteromonadaceae 1236|Gammaproteobacteria S Peptidase family M28 - - - - - - - - - - - - PA,Peptidase_M28 k141_15938_5 1042377.AFPJ01000002_gene514 1.14e-99 294.0 COG0204@1|root,COG0204@2|Bacteria,1RJMS@1224|Proteobacteria,1S71V@1236|Gammaproteobacteria,467SS@72275|Alteromonadaceae 1236|Gammaproteobacteria I Phosphate acyltransferases - - - - - - - - - - - - Acyltransferase k141_15938_6 1453501.JELR01000001_gene3269 0.0 998.0 COG4108@1|root,COG4108@2|Bacteria,1MU7X@1224|Proteobacteria,1RMFT@1236|Gammaproteobacteria,4641Z@72275|Alteromonadaceae 1236|Gammaproteobacteria J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP prfC GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019538,GO:0022411,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032984,GO:0034641,GO:0034645,GO:0036094,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02837 - - - - ko00000,ko03012 - - - GTP_EFTU,GTP_EFTU_D2,RF3_C k141_15938_7 1279017.AQYJ01000022_gene2569 1.4e-314 870.0 COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,1RPQD@1236|Gammaproteobacteria,469F1@72275|Alteromonadaceae 1236|Gammaproteobacteria E Creatinase/Prolidase N-terminal domain ampP - 3.4.11.9 ko:K01262 - - - - ko00000,ko01000,ko01002 - - - Creatinase_N,Creatinase_N_2,Peptidase_M24,Peptidase_M24_C k141_15938_8 1453501.JELR01000001_gene3271 8.46e-138 402.0 COG2267@1|root,COG2267@2|Bacteria,1R41P@1224|Proteobacteria,1T1IM@1236|Gammaproteobacteria,467KZ@72275|Alteromonadaceae 1236|Gammaproteobacteria I Serine aminopeptidase, S33 - - - - - - - - - - - - Abhydrolase_1 k141_15938_9 1279017.AQYJ01000022_gene2578 7.92e-63 206.0 COG0534@1|root,COG0534@2|Bacteria,1MVRV@1224|Proteobacteria,1RRDQ@1236|Gammaproteobacteria,46495@72275|Alteromonadaceae 1236|Gammaproteobacteria V COG0534 Na -driven multidrug efflux pump - - - - - - - - - - - - MatE k141_5361_1 218284.CCDN010000006_gene3630 9.19e-106 311.0 COG1660@1|root,COG1660@2|Bacteria,1TPS4@1239|Firmicutes,4H9KM@91061|Bacilli,1ZCWE@1386|Bacillus 91061|Bacilli S Displays ATPase and GTPase activities yvcJ - - ko:K06958 - - - - ko00000,ko03019 - - - ATP_bind_2 k141_5361_2 218284.CCDN010000006_gene3631 1.53e-30 110.0 COG1051@1|root,COG1051@2|Bacteria,1V3BX@1239|Firmicutes,4HGE6@91061|Bacilli,1ZFT4@1386|Bacillus 91061|Bacilli F Nudix hydrolase yvcI - 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - - NUDIX k141_12598_1 666685.R2APBS1_0936 2.39e-81 266.0 COG3227@1|root,COG3227@2|Bacteria,1P416@1224|Proteobacteria,1RR7I@1236|Gammaproteobacteria,1X4PD@135614|Xanthomonadales 135614|Xanthomonadales E Zinc metalloprotease (Elastase) - - 3.4.24.25,3.4.24.26 ko:K01399,ko:K08604 ko01503,ko02024,ko05110,ko05111,map01503,map02024,map05110,map05111 - - - ko00000,ko00001,ko01000,ko01002 - - - FTP,PPC,P_proprotein,PepSY,Peptidase_M4,Peptidase_M4_C k141_35026_2 1396.DJ87_986 1.63e-14 79.0 COG4372@1|root,COG5280@1|root,COG4372@2|Bacteria,COG5280@2|Bacteria,1UHTF@1239|Firmicutes,4IS94@91061|Bacilli 91061|Bacilli S Tail tape measure protein, TP901 family - - - - - - - - - - - - PhageMin_Tail k141_21906_5 298386.PBPRA1504 3.02e-25 111.0 2EET6@1|root,32M24@2|Bacteria,1Q8K2@1224|Proteobacteria,1TJMV@1236|Gammaproteobacteria,1Y1EZ@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_21906_8 583345.Mmol_1850 6.07e-16 82.8 2DNJJ@1|root,32XU7@2|Bacteria,1N0AU@1224|Proteobacteria,2VU15@28216|Betaproteobacteria 28216|Betaproteobacteria S Protein of unknown function (DUF2971) - - - - - - - - - - - - DUF2971 k141_21906_9 1190603.AJYD01000005_gene4014 8.51e-63 201.0 28MDS@1|root,2ZARK@2|Bacteria,1N853@1224|Proteobacteria,1T0R5@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF4145) - - - - - - - - - - - - DUF4145 k141_21906_10 1547445.LO80_06040 1.36e-156 446.0 2DBGM@1|root,2Z958@2|Bacteria,1R715@1224|Proteobacteria,1SR3R@1236|Gammaproteobacteria 1236|Gammaproteobacteria S TIR domain - - - - - - - - - - - - TIR_2 k141_20702_2 279010.BL02946 3.05e-46 152.0 2CICC@1|root,32S7S@2|Bacteria,1VC46@1239|Firmicutes,4HKPJ@91061|Bacilli,1ZI00@1386|Bacillus 91061|Bacilli - - yneQ - - - - - - - - - - - - k141_37290_1 42565.FP66_12035 3.82e-93 280.0 COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,1RNZZ@1236|Gammaproteobacteria,1XIE0@135619|Oceanospirillales 135619|Oceanospirillales F Phosphoribosylformylglycinamidine cyclo-ligase purM - 6.3.3.1 ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04208 RC01100 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C k141_37290_2 768066.HELO_2291 1.37e-11 62.8 COG0299@1|root,COG0299@2|Bacteria,1MWN1@1224|Proteobacteria,1RMHS@1236|Gammaproteobacteria,1XJ71@135619|Oceanospirillales 135619|Oceanospirillales F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate purN - 2.1.2.2 ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04325,R04326 RC00026,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 - - - Formyl_trans_N k141_2855_1 1391647.AVSV01000003_gene1694 1.35e-10 60.1 COG5546@1|root,COG5546@2|Bacteria,1VJ2E@1239|Firmicutes,24R32@186801|Clostridia,36MN4@31979|Clostridiaceae 186801|Clostridia S COG5546 Small integral membrane protein - - - - - - - - - - - - Phage_holin_1 k141_2855_2 1033738.CAEP01000156_gene4214 6.37e-25 102.0 COG5632@1|root,COG5632@2|Bacteria,1V3JT@1239|Firmicutes,4HJQH@91061|Bacilli,26G7X@186818|Planococcaceae 91061|Bacilli M Ami_2 - - 3.5.1.28 ko:K01447 - - R04112 RC00064,RC00141 ko00000,ko01000 - - - Amidase_2,PG_binding_1 k141_25590_2 1499685.CCFJ01000029_gene2187 1.29e-118 342.0 COG1051@1|root,COG1051@2|Bacteria,1U7WX@1239|Firmicutes,4HHQT@91061|Bacilli,1ZD9E@1386|Bacillus 91061|Bacilli F ADP-ribose pyrophosphatase yjhB - 3.6.1.13 ko:K01515 ko00230,map00230 - R01054 RC00002 ko00000,ko00001,ko01000 - - - NUDIX,Nudix_N k141_32490_2 218284.CCDN010000002_gene2389 6.04e-133 377.0 COG0450@1|root,COG0450@2|Bacteria,1TQU7@1239|Firmicutes,4HA2M@91061|Bacilli,1ZCZP@1386|Bacillus 91061|Bacilli O Alkyl hydroperoxide reductase ahpC - 1.11.1.15 ko:K03386 ko04214,map04214 - - - ko00000,ko00001,ko01000,ko04147 - - - 1-cysPrx_C,AhpC-TSA k141_32507_2 218284.CCDN010000002_gene2086 3.1e-116 338.0 COG3396@1|root,COG3396@2|Bacteria,1TPWQ@1239|Firmicutes,4HCRX@91061|Bacilli,1ZB84@1386|Bacillus 91061|Bacilli Q Phenylacetic acid catabolic protein paaC - 1.14.13.149 ko:K02611 ko00360,ko01120,map00360,map01120 - R09838 RC02690 ko00000,ko00001,ko01000 - - - PaaA_PaaC k141_10170_1 218284.CCDN010000002_gene2041 1.58e-102 317.0 COG1277@1|root,COG1277@2|Bacteria,1TRJ8@1239|Firmicutes,4HA9I@91061|Bacilli,1ZCXM@1386|Bacillus 91061|Bacilli S ABC-type transport system involved in multi-copper enzyme maturation permease component - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - - k141_8936_1 1280001.BAOA01000022_gene622 6.36e-315 890.0 COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,1SP6I@1236|Gammaproteobacteria,1XUED@135623|Vibrionales 135623|Vibrionales P Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family cusA - - ko:K07787 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.6.1.4 - - ACR_tran k141_8936_2 1453501.JELR01000002_gene1173 2.62e-122 362.0 COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,1RMR6@1236|Gammaproteobacteria,4642Y@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Tripartite ATP-independent periplasmic transporter, DctM component gtrB - - - - - - - - - - - DctM k141_7608_2 1279017.AQYJ01000013_gene2982 9.03e-101 293.0 COG0049@1|root,COG0049@2|Bacteria,1MXC8@1224|Proteobacteria,1RN77@1236|Gammaproteobacteria,466NR@72275|Alteromonadaceae 1236|Gammaproteobacteria J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA rpsG GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - ko:K02992 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S7 k141_7608_3 1042377.AFPJ01000006_gene2114 0.0 1286.0 COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,1RNSZ@1236|Gammaproteobacteria,4648C@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome fusA GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02355 - - - - ko00000,ko03012,ko03029 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 k141_26932_1 441769.ABFU01000049_gene3701 2.26e-71 223.0 COG0497@1|root,COG0497@2|Bacteria,1VUIK@1239|Firmicutes,4HVGZ@91061|Bacilli 91061|Bacilli L DNA recombination - - - - - - - - - - - - - k141_25621_1 218284.CCDN010000001_gene132 6.64e-99 316.0 COG1038@1|root,COG1038@2|Bacteria,1UHP9@1239|Firmicutes,4IS56@91061|Bacilli,1ZC4R@1386|Bacillus 91061|Bacilli C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second pyc - 6.4.1.1 ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 M00173 R00344 RC00040,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,HMGL-like,PYC_OADA k141_6528_2 1313301.AUGC01000008_gene386 5.12e-49 169.0 COG0156@1|root,COG0156@2|Bacteria,4NFBU@976|Bacteroidetes 976|Bacteroidetes E Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA kbl - 2.3.1.29 ko:K00639 ko00260,map00260 - R00371 RC00004,RC00394 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 k141_14733_1 1294265.JCM21738_2732 4.1e-111 327.0 COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,1TRC3@1239|Firmicutes,4HADQ@91061|Bacilli,1ZAP8@1386|Bacillus 91061|Bacilli C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) ctaC GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.9.3.1 ko:K02275 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.4,3.D.4.6 - - COX2,COX2_TM,Cytochrom_C,Cytochrome_CBB3 k141_23250_3 1007103.AFHW01000034_gene2010 1.48e-15 76.3 2EVWJ@1|root,33PA8@2|Bacteria,1VNYN@1239|Firmicutes,4IRMI@91061|Bacilli,272CN@186822|Paenibacillaceae 91061|Bacilli - - - - - - - - - - - - - - - k141_30131_2 218284.CCDN010000001_gene1090 5.68e-53 170.0 COG5581@1|root,COG5581@2|Bacteria,1V31U@1239|Firmicutes,4HGFE@91061|Bacilli,1ZCCG@1386|Bacillus 91061|Bacilli M Flagellar protein YcgR ypfA - - - - - - - - - - - PilZ,YcgR_2 k141_37314_1 1047013.AQSP01000073_gene1094 3.41e-42 153.0 COG3844@1|root,COG3844@2|Bacteria,2NS52@2323|unclassified Bacteria 2|Bacteria E Aminotransferase class-V - - 3.7.1.3 ko:K01556 ko00380,ko01100,map00380,map01100 M00038 R00987,R02668,R03936 RC00284,RC00415 ko00000,ko00001,ko00002,ko01000 - - - Aminotran_5 k141_15963_1 1121875.KB907553_gene20 3.16e-191 549.0 COG5361@1|root,COG5361@2|Bacteria,4NKSK@976|Bacteroidetes,1IARY@117743|Flavobacteriia 976|Bacteroidetes S Protein of unknown function (DUF1254) - - - - - - - - - - - - DUF1214,DUF1254 k141_10171_1 218284.CCDN010000001_gene678 1.29e-104 309.0 COG1277@1|root,COG1277@2|Bacteria,1TT9E@1239|Firmicutes,4HE5W@91061|Bacilli,1ZDPM@1386|Bacillus 91061|Bacilli S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component yhcI - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_2,ABC2_membrane_4 k141_27719_1 1219076.N646_1610 2.55e-71 227.0 COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RMFF@1236|Gammaproteobacteria,1XT11@135623|Vibrionales 135623|Vibrionales C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes lpdA GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0045250,GO:0045254,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyr_redox_2,Pyr_redox_dim k141_27719_2 1116375.VEJY3_12990 1.35e-139 395.0 COG1309@1|root,COG1309@2|Bacteria,1N3KN@1224|Proteobacteria,1SA7U@1236|Gammaproteobacteria,1XV8I@135623|Vibrionales 135623|Vibrionales K Transcriptional regulator luxR - - ko:K10913 ko02020,ko02024,ko05111,map02020,map02024,map05111 - - - ko00000,ko00001,ko03000 - - - TetR_N k141_27719_3 223926.28807513 1.02e-118 340.0 COG0634@1|root,COG0634@2|Bacteria,1NRT8@1224|Proteobacteria,1RNPQ@1236|Gammaproteobacteria,1XT05@135623|Vibrionales 135623|Vibrionales F Belongs to the purine pyrimidine phosphoribosyltransferase family hpt - 2.4.2.8 ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 - R00190,R01132,R01229,R02142,R08237,R08238,R08245 RC00063,RC00122 ko00000,ko00001,ko01000 - - - Pribosyltran k141_27719_4 1280001.BAOA01000080_gene3052 3.99e-157 441.0 COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,1RSY6@1236|Gammaproteobacteria,1XTY7@135623|Vibrionales 135623|Vibrionales P Reversible hydration of carbon dioxide can - 4.2.1.1 ko:K01673 ko00910,map00910 - R00132,R10092 RC02807 ko00000,ko00001,ko01000 - - - Pro_CA k141_27719_5 1116375.VEJY3_12975 0.0 996.0 COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,1RMCN@1236|Gammaproteobacteria,1XW6V@135623|Vibrionales 135623|Vibrionales P COG0659 Sulfate permease and related transporters (MFS superfamily) - - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - STAS,Sulfate_transp k141_27719_6 223926.28807509 2.12e-200 557.0 COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,1RMC5@1236|Gammaproteobacteria,1XSXH@135623|Vibrionales 135623|Vibrionales V COG1131 ABC-type multidrug transport system, ATPase component yadG - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_27719_7 223926.28807508 3.64e-172 481.0 COG0842@1|root,COG0842@2|Bacteria,1MUH1@1224|Proteobacteria,1RP0Z@1236|Gammaproteobacteria,1XSC8@135623|Vibrionales 135623|Vibrionales V Transport permease protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane k141_27719_8 223926.28807505 1.98e-187 524.0 COG0414@1|root,COG0414@2|Bacteria,1MV1S@1224|Proteobacteria,1RMEG@1236|Gammaproteobacteria,1XT8P@135623|Vibrionales 135623|Vibrionales H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate panC GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 M00119 R02473 RC00096,RC00141 ko00000,ko00001,ko00002,ko01000 - - - Pantoate_ligase k141_27719_9 223926.28807504 1.56e-186 518.0 COG0413@1|root,COG0413@2|Bacteria,1MU3B@1224|Proteobacteria,1RM8D@1236|Gammaproteobacteria,1XSV3@135623|Vibrionales 135623|Vibrionales H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate panB GO:0003674,GO:0003824,GO:0003864,GO:0006082,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016740,GO:0016741,GO:0016742,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576 2.1.2.11 ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R01226 RC00022,RC00200 ko00000,ko00001,ko00002,ko01000 - - - Pantoate_transf k141_27719_10 1116375.VEJY3_12950 2.47e-105 305.0 COG0801@1|root,COG0801@2|Bacteria,1MZH8@1224|Proteobacteria,1S63J@1236|Gammaproteobacteria,1XVS1@135623|Vibrionales 135623|Vibrionales H COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase folK - 2.7.6.3 ko:K00950 ko00790,ko01100,map00790,map01100 M00126,M00841 R03503 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - HPPK k141_27719_11 1116375.VEJY3_12945 3.39e-315 860.0 COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,1RMBG@1236|Gammaproteobacteria,1XT38@135623|Vibrionales 135623|Vibrionales F Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control pcnB - 2.7.7.19 ko:K00970 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - PolyA_pol,PolyA_pol_RNAbd,PolyA_pol_arg_C k141_27719_12 1116375.VEJY3_12940 6.6e-195 541.0 COG0008@1|root,COG0008@2|Bacteria,1MUN7@1224|Proteobacteria,1RMYQ@1236|Gammaproteobacteria,1XTZH@135623|Vibrionales 135623|Vibrionales J Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon gluQ - - ko:K01894 - - - - ko00000,ko01000,ko01007,ko03016 - - - tRNA-synt_1c k141_27719_13 223926.28807498 8.21e-100 290.0 COG1734@1|root,COG1734@2|Bacteria,1RD08@1224|Proteobacteria,1S47H@1236|Gammaproteobacteria,1XTC3@135623|Vibrionales 135623|Vibrionales T Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression dksA - - ko:K06204 ko02026,map02026 - - - ko00000,ko00001,ko03000,ko03009,ko03021 - - - zf-dskA_traR k141_27719_14 1116375.VEJY3_12930 4.94e-162 454.0 COG1489@1|root,COG1489@2|Bacteria,1MUC3@1224|Proteobacteria,1RQ95@1236|Gammaproteobacteria,1XTR1@135623|Vibrionales 135623|Vibrionales S Belongs to the SfsA family sfsA GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005975,GO:0008150,GO:0008152,GO:0044238,GO:0071704,GO:0097159,GO:1901363 - ko:K06206 - - - - ko00000 - - - SfsA k141_684_1 218284.CCDN010000002_gene2334 4.54e-181 517.0 COG4632@1|root,COG4632@2|Bacteria,1UV25@1239|Firmicutes,4I5JA@91061|Bacilli,1ZEFI@1386|Bacillus 91061|Bacilli G Phosphodiester glycosidase - - - - - - - - - - - - NAGPA,SPOR k141_5383_1 313606.M23134_04933 1.59e-67 230.0 COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,47N6C@768503|Cytophagia 976|Bacteroidetes V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran k141_19598_1 218284.CCDN010000004_gene3133 2.84e-152 442.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,1ZBXB@1386|Bacillus 91061|Bacilli V COG1132 ABC-type multidrug transport system, ATPase and permease components yheI - - ko:K18216,ko:K18889 ko02010,map02010 M00635,M00707 - - ko00000,ko00001,ko00002,ko01504,ko02000 3.A.1,3.A.1.106.13,3.A.1.106.5 - - ABC_membrane,ABC_tran k141_8938_1 1461580.CCAS010000015_gene1868 1.82e-72 224.0 COG0363@1|root,COG0363@2|Bacteria,1TP10@1239|Firmicutes,4HAG4@91061|Bacilli,1ZD28@1386|Bacillus 91061|Bacilli G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion nagB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 3.5.99.6 ko:K02564 ko00520,ko01100,map00520,map01100 - R00765 RC00163 ko00000,ko00001,ko01000 - - iYO844.BSU35020 Glucosamine_iso k141_33846_1 406124.ACPC01000047_gene1812 3.73e-80 257.0 COG1033@1|root,COG1033@2|Bacteria,1VSWA@1239|Firmicutes,4HBIV@91061|Bacilli 91061|Bacilli S MMPL family ydfJ - - ko:K07003 - - - - ko00000 - - - MMPL k141_17144_1 935837.JAEK01000019_gene759 5.66e-83 251.0 COG3279@1|root,COG3279@2|Bacteria,1V14X@1239|Firmicutes,4HDIC@91061|Bacilli,1ZC3U@1386|Bacillus 91061|Bacilli T COG3279 Response regulator of the LytR AlgR family - - - ko:K07705 ko02020,map02020 M00492 - - ko00000,ko00001,ko00002,ko02022 - - - LytTR,Response_reg k141_11336_1 1462527.CCDM010000002_gene635 4.63e-65 206.0 COG1660@1|root,COG1660@2|Bacteria,1V36M@1239|Firmicutes,4HFUJ@91061|Bacilli,23M2S@182709|Oceanobacillus 91061|Bacilli S AAA domain - - - - - - - - - - - - AAA_18,AAA_33 k141_10173_1 796606.BMMGA3_12975 5.54e-131 390.0 COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,4HABZ@91061|Bacilli,1ZB5W@1386|Bacillus 91061|Bacilli J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) thrS GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD k141_686_1 218284.CCDN010000002_gene2910 5.66e-52 170.0 2EA57@1|root,334A4@2|Bacteria,1VHEA@1239|Firmicutes,4HQZU@91061|Bacilli,1ZIXN@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_7609_2 1279017.AQYJ01000020_gene1332 4.91e-17 79.0 COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,1RNCA@1236|Gammaproteobacteria,464X7@72275|Alteromonadaceae 1236|Gammaproteobacteria E Serine acetyltransferase, N-terminal cysE GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009001,GO:0009058,GO:0009069,GO:0009070,GO:0009314,GO:0009333,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016053,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019344,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.3.1.30 ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 M00021 R00586 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,SATase_N k141_18480_1 218284.CCDN010000001_gene1170 5.53e-74 223.0 COG1406@1|root,COG1406@2|Bacteria,1V9SN@1239|Firmicutes,4HJCY@91061|Bacilli,1ZH5Y@1386|Bacillus 91061|Bacilli N Chemotaxis phosphatase CheX cheX - - ko:K03409 ko02030,map02030 - - - ko00000,ko00001,ko02035 - - - CheC,CheX k141_6531_1 218284.CCDN010000001_gene1814 3.35e-62 208.0 COG2508@1|root,COG2508@2|Bacteria,1TSQP@1239|Firmicutes,4HB10@91061|Bacilli,1ZBH4@1386|Bacillus 91061|Bacilli QT Purine catabolism regulatory protein-like family - - - ko:K09684 - - - - ko00000,ko03000 - - - HTH_30,PucR k141_32508_2 1279017.AQYJ01000020_gene1315 2.62e-174 491.0 COG0119@1|root,COG0119@2|Bacteria,1MUMX@1224|Proteobacteria,1RMUX@1236|Gammaproteobacteria,4641B@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0119 Isopropylmalate homocitrate citramalate synthases mvaB - 4.1.3.4 ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 M00036,M00088 R01360,R08090 RC00502,RC00503,RC01118,RC01946 ko00000,ko00001,ko00002,ko01000 - - - HMGL-like k141_32508_3 1279017.AQYJ01000020_gene1309 3.86e-28 112.0 COG5339@1|root,COG5339@2|Bacteria,1QPEJ@1224|Proteobacteria,1SJ4D@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Bacterial protein of unknown function (DUF945) - - - - - - - - - - - - DUF945 k141_24270_1 1116375.VEJY3_03670 4.56e-69 215.0 COG1028@1|root,COG1028@2|Bacteria,1MUCH@1224|Proteobacteria,1RNAA@1236|Gammaproteobacteria,1XTR2@135623|Vibrionales 135623|Vibrionales IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) ybbO - - - - - - - - - - - adh_short k141_24270_2 1116375.VEJY3_03675 4.49e-155 439.0 COG1090@1|root,COG1090@2|Bacteria,1MUB4@1224|Proteobacteria,1RN6A@1236|Gammaproteobacteria,1XSDX@135623|Vibrionales 135623|Vibrionales S nucleoside-diphosphate sugar epimerase yfcH - - ko:K07071 - - - - ko00000 - - - DUF1731,Epimerase k141_37317_1 42565.FP66_02365 4.91e-106 312.0 COG0583@1|root,COG0583@2|Bacteria,1MVA1@1224|Proteobacteria,1RPAJ@1236|Gammaproteobacteria,1XIF6@135619|Oceanospirillales 135619|Oceanospirillales K transcriptional regulator oxyR - - ko:K04761 ko02026,map02026 - - - ko00000,ko00001,ko03000 - - - HTH_1,LysR_substrate k141_14736_1 42565.FP66_05240 1.37e-104 312.0 COG0683@1|root,COG0683@2|Bacteria,1MWJ1@1224|Proteobacteria,1RP5V@1236|Gammaproteobacteria,1XM82@135619|Oceanospirillales 135619|Oceanospirillales E Amino acid ABC transporter substrate-binding protein - - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 k141_25625_1 1307436.PBF_05173 7.25e-111 328.0 COG0381@1|root,COG0381@2|Bacteria,1TQZT@1239|Firmicutes,4HBI3@91061|Bacilli,1ZCZG@1386|Bacillus 91061|Bacilli M Belongs to the UDP-N-acetylglucosamine 2-epimerase family mnaA - 5.1.3.14 ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 M00362 R00420 RC00290 ko00000,ko00001,ko00002,ko01000,ko01005 - - iSB619.SA_RS11005 Epimerase_2 k141_19599_1 1196031.ALEG01000039_gene1288 4.07e-79 249.0 COG2369@1|root,COG2369@2|Bacteria,1V2JT@1239|Firmicutes,4HFSR@91061|Bacilli,1ZIIA@1386|Bacillus 91061|Bacilli S Phage Mu protein F like protein - - - - - - - - - - - - Phage_Mu_F k141_23511_1 1116375.VEJY3_08265 0.0 881.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,1XSW9@135623|Vibrionales 135623|Vibrionales C Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid gabD - 1.2.1.16,1.2.1.20,1.2.1.79 ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 M00027 R00713,R00714,R02401 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_3049_1 586416.GZ22_13470 8.45e-81 253.0 COG1621@1|root,COG1621@2|Bacteria,1TR8C@1239|Firmicutes,4HBYU@91061|Bacilli 91061|Bacilli G Belongs to the glycosyl hydrolase 68 family sacB GO:0005575,GO:0005576 2.4.1.10,2.4.1.9 ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 - R04194,R05140 RC00077,RC00247 ko00000,ko00001,ko01000,ko01003 - GH68 - Glyco_hydro_68,Gram_pos_anchor,SH3_8 k141_27185_1 218284.CCDN010000001_gene1362 5.54e-146 429.0 COG1193@1|root,COG1193@2|Bacteria,1TQWB@1239|Firmicutes,4HAHW@91061|Bacilli,1ZC6C@1386|Bacillus 91061|Bacilli L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity mutS1 - - ko:K07456 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_V k141_12833_1 483219.LILAB_31685 5.73e-52 179.0 COG3193@1|root,COG3193@2|Bacteria,1QX6Y@1224|Proteobacteria,43BZP@68525|delta/epsilon subdivisions,2X7AG@28221|Deltaproteobacteria,2YU0D@29|Myxococcales 28221|Deltaproteobacteria S SusD family - - - ko:K21572 - - - - ko00000,ko02000 8.A.46.1,8.A.46.3 - - SusD_RagB k141_9200_1 218284.CCDN010000001_gene495 2e-66 213.0 COG0477@1|root,COG2814@2|Bacteria,1TQXU@1239|Firmicutes,4HAYB@91061|Bacilli,1ZQ77@1386|Bacillus 91061|Bacilli EGP -transporter ytbD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K19577 - - - - ko00000,ko02000 2.A.1.2.65 - - MFS_1,Sugar_tr k141_30301_1 218284.CCDN010000002_gene2907 5.19e-55 188.0 COG0753@1|root,COG0753@2|Bacteria,1TPPV@1239|Firmicutes,4H9XQ@91061|Bacilli,1ZB44@1386|Bacillus 91061|Bacilli P serves to protect cells from the toxic effects of hydrogen peroxide katE GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0042221,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070887,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1990748 1.11.1.6 ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 M00532 R00009,R00602,R02670 RC00034,RC00767,RC02141,RC02755 ko00000,ko00001,ko00002,ko01000 - - - Catalase,Catalase-rel,DJ-1_PfpI k141_27916_1 391625.PPSIR1_00802 5.33e-70 227.0 COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,42N6N@68525|delta/epsilon subdivisions,2WJ1W@28221|Deltaproteobacteria,2YUFG@29|Myxococcales 28221|Deltaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain nuoF-2 - 1.6.5.3 ko:K00334,ko:K00335 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - 2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB k141_14101_1 1384049.CD29_11105 8.09e-34 119.0 COG0816@1|root,COG0816@2|Bacteria,1V6ER@1239|Firmicutes,4HH04@91061|Bacilli,3IXXT@400634|Lysinibacillus 91061|Bacilli L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA yrrK GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - ko:K07447 - - - - ko00000,ko01000 - - - RuvX k141_10393_1 1385514.N782_12480 8.84e-82 270.0 COG0454@1|root,COG0456@2|Bacteria,1TQQA@1239|Firmicutes,4HBXN@91061|Bacilli,2YBGI@289201|Pontibacillus 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10 k141_19823_1 1294265.JCM21738_5506 4.51e-123 355.0 COG2755@1|root,COG2755@2|Bacteria,1UZKM@1239|Firmicutes,4HVJ0@91061|Bacilli,1ZEST@1386|Bacillus 91061|Bacilli E GDSL-like Lipase/Acylhydrolase - - - - - - - - - - - - Lipase_GDSL_2 k141_18777_1 218284.CCDN010000001_gene219 5.15e-187 531.0 COG1574@1|root,COG1574@2|Bacteria,1TQ6G@1239|Firmicutes,4H9T6@91061|Bacilli,1ZBDY@1386|Bacillus 91061|Bacilli S amidohydrolase nfdA_1 - - - - - - - - - - - Amidohydro_3 k141_5666_1 218284.CCDN010000008_gene4229 1.08e-25 105.0 COG3383@1|root,COG3383@2|Bacteria,1UHTX@1239|Firmicutes,4IPM7@91061|Bacilli,1ZRCN@1386|Bacillus 91061|Bacilli C formate dehydrogenase, alpha subunit - - 1.17.1.9 ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001,ko01000 - - - Fer2_4,Fer4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3 k141_5666_2 218284.CCDN010000008_gene4230 1.92e-163 460.0 COG1526@1|root,COG1526@2|Bacteria,1TU8R@1239|Firmicutes,4HAY8@91061|Bacilli,1ZBNJ@1386|Bacillus 91061|Bacilli C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH fdhD - - ko:K02379 - - - - ko00000 - - - FdhD-NarQ k141_3050_1 1294265.JCM21738_2852 4.34e-49 160.0 2E87Y@1|root,332M1@2|Bacteria,1VHQ0@1239|Firmicutes,4HNRH@91061|Bacilli,1ZJI7@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_3050_2 1294265.JCM21738_2853 7.76e-38 130.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HAWZ@91061|Bacilli,1ZN1Q@1386|Bacillus 91061|Bacilli I Acyl-CoA dehydrogenase, N-terminal domain - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_18778_1 42565.FP66_11910 6.36e-42 151.0 COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,1RN6Z@1236|Gammaproteobacteria,1XIGC@135619|Oceanospirillales 135619|Oceanospirillales L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage uvrB - - ko:K03702 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - Helicase_C,ResIII,UVR,UvrB k141_18778_2 42565.FP66_11915 4.11e-74 223.0 COG1765@1|root,COG1765@2|Bacteria,1N2BT@1224|Proteobacteria,1S90N@1236|Gammaproteobacteria,1XIT2@135619|Oceanospirillales 135619|Oceanospirillales O OsmC-like protein - - - ko:K07397 - - - - ko00000 - - - OsmC k141_1843_1 399739.Pmen_3824 0.000238 45.4 2EKQ7@1|root,33EDZ@2|Bacteria,1NHK0@1224|Proteobacteria,1SAXC@1236|Gammaproteobacteria,1YH77@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S Protein of unknown function (DUF2845) - - - - - - - - - - - - DUF2845 k141_11619_1 218284.CCDN010000002_gene2194 1.66e-77 234.0 COG5012@1|root,COG5012@2|Bacteria,1V5DK@1239|Firmicutes,4HJ9Z@91061|Bacilli,1ZFGI@1386|Bacillus 91061|Bacilli S B12 binding domain - - - - - - - - - - - - B12-binding,B12-binding_2 k141_11619_2 218284.CCDN010000002_gene2195 4.42e-128 362.0 COG0780@1|root,COG0780@2|Bacteria,1TPYC@1239|Firmicutes,4HB14@91061|Bacilli,1ZB8C@1386|Bacillus 91061|Bacilli S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) queF - 1.7.1.13 ko:K09457 ko00790,ko01100,map00790,map01100 - R07605 RC01875 ko00000,ko00001,ko01000,ko03016 - - - QueF k141_23512_1 1211777.BN77_1622 2.86e-19 86.3 COG3637@1|root,COG3637@2|Bacteria,1R3Z1@1224|Proteobacteria,2U1SQ@28211|Alphaproteobacteria,4BAX2@82115|Rhizobiaceae 28211|Alphaproteobacteria M Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - - - - - - - - - - OMP_b-brl k141_20879_1 95619.PM1_0205685 1.36e-18 87.8 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria 1236|Gammaproteobacteria T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains pilR - - ko:K02481,ko:K02667 ko02020,map02020 M00501 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - HTH_8,Response_reg,Sigma54_activat k141_20879_2 1168065.DOK_01634 1.15e-20 89.4 COG4968@1|root,COG4968@2|Bacteria,1N6QE@1224|Proteobacteria,1SCBS@1236|Gammaproteobacteria,1JAKT@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria NU COG4968 Tfp pilus assembly protein PilE pilE - - ko:K02655 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - ComP_DUS,N_methyl k141_20879_3 1134474.O59_001106 2.43e-14 74.3 COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,1RPV3@1236|Gammaproteobacteria,1FGTE@10|Cellvibrio 1236|Gammaproteobacteria NU Neisseria PilC beta-propeller domain - - - ko:K02674 - - - - ko00000,ko02035,ko02044 - - - Neisseria_PilC,PA14 k141_9202_1 218284.CCDN010000008_gene4138 1.69e-49 164.0 COG1734@1|root,COG1734@2|Bacteria,1V4KF@1239|Firmicutes,4HHBC@91061|Bacilli,1ZQQT@1386|Bacillus 91061|Bacilli T Prokaryotic dksA/traR C4-type zinc finger - - - - - - - - - - - - zf-dskA_traR k141_7843_1 387093.SUN_1048 2e-56 186.0 COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,42MFD@68525|delta/epsilon subdivisions,2YN54@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria K NAD-dependent protein deacetylase, SIR2 family - - - - - - - - - - - - SIR2 k141_7843_2 1453501.JELR01000001_gene2101 1.1e-44 147.0 COG3012@1|root,COG3012@2|Bacteria,1MZZK@1224|Proteobacteria,1S9FV@1236|Gammaproteobacteria,468GH@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria ychJ - - ko:K09858 - - - - ko00000 - - - SEC-C k141_22180_2 396588.Tgr7_0491 0.000343 47.0 COG1247@1|root,COG1247@2|Bacteria 2|Bacteria M phosphinothricin N-acetyltransferase activity yafP - - ko:K03830 - - - - ko00000,ko01000 - - - Acetyltransf_1,Acetyltransf_10 k141_27221_1 218284.CCDN010000001_gene974 1.24e-142 417.0 COG0497@1|root,COG0497@2|Bacteria,1TP99@1239|Firmicutes,4H9ZR@91061|Bacilli,1ZC8B@1386|Bacillus 91061|Bacilli L May be involved in recombinational repair of damaged DNA recN GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - ko:K03631 - - - - ko00000,ko03400 - - - AAA_23,SMC_N k141_9226_1 926550.CLDAP_27060 4.07e-51 185.0 COG0366@1|root,COG4733@1|root,COG0366@2|Bacteria,COG4733@2|Bacteria,2G7WY@200795|Chloroflexi 200795|Chloroflexi G Belongs to the glycosyl hydrolase 13 family - - - - - - - - - - - - Alpha-amylase,CBM_20,fn3 k141_6792_1 1144275.COCOR_02419 3.4e-35 126.0 COG0634@1|root,COG0634@2|Bacteria,1NRT8@1224|Proteobacteria,42SNI@68525|delta/epsilon subdivisions,2WPFN@28221|Deltaproteobacteria,2YV3U@29|Myxococcales 28221|Deltaproteobacteria F Belongs to the purine pyrimidine phosphoribosyltransferase family hpt - 2.4.2.8 ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 - R00190,R01132,R01229,R02142,R08237,R08238,R08245 RC00063,RC00122 ko00000,ko00001,ko01000 - - - Pribosyltran k141_20891_1 1042377.AFPJ01000007_gene1866 9.46e-230 652.0 COG1770@1|root,COG1770@2|Bacteria,1MUED@1224|Proteobacteria,1RMSV@1236|Gammaproteobacteria,464IJ@72275|Alteromonadaceae 1236|Gammaproteobacteria E Prolyl oligopeptidase, N-terminal beta-propeller domain ptrB GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0070011,GO:0070012,GO:0071704,GO:0140096,GO:1901564 3.4.21.83 ko:K01354 ko05142,ko05143,map05142,map05143 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S9,Peptidase_S9_N k141_20891_2 864702.OsccyDRAFT_1759 1.12e-10 68.9 COG0639@1|root,COG0639@2|Bacteria,1G03S@1117|Cyanobacteria,1H7M5@1150|Oscillatoriales 1117|Cyanobacteria T PFAM Calcineurin-like phosphoesterase - - 3.1.3.16 ko:K07313 - - - - ko00000,ko01000 - - - Metallophos k141_20891_3 1005048.CFU_3459 1.14e-162 473.0 COG1028@1|root,COG1028@2|Bacteria,1MXRY@1224|Proteobacteria,2VMYM@28216|Betaproteobacteria,4768U@75682|Oxalobacteraceae 28216|Betaproteobacteria IQ KR domain - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 k141_35330_1 1453501.JELR01000002_gene487 5.18e-61 199.0 2AFXB@1|root,3160U@2|Bacteria,1RI5S@1224|Proteobacteria,1S87Z@1236|Gammaproteobacteria,467M3@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_35330_2 1453501.JELR01000002_gene486 1.63e-34 132.0 COG1629@1|root,COG4771@2|Bacteria,1MUWN@1224|Proteobacteria,1S005@1236|Gammaproteobacteria,46A62@72275|Alteromonadaceae 1236|Gammaproteobacteria P Outer membrane protein beta-barrel family - - - - - - - - - - - - Plug,TonB_dep_Rec k141_32760_2 674977.VMC_36490 1.15e-92 272.0 2B0X8@1|root,31TA1@2|Bacteria,1QJF5@1224|Proteobacteria,1THEH@1236|Gammaproteobacteria,1XUWB@135623|Vibrionales 135623|Vibrionales - - VPA0789 - - - - - - - - - - - - k141_32760_3 29495.EA26_11190 1.16e-84 272.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XSE1@135623|Vibrionales 135623|Vibrionales T COG2202 FOG PAS PAC domain - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - MCPsignal,PAS_3 k141_29283_1 1294265.JCM21738_3343 2.63e-131 382.0 COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,4HAM7@91061|Bacilli,1ZBG8@1386|Bacillus 91061|Bacilli E COG0747 ABC-type dipeptide transport system, periplasmic component dppA - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 k141_14129_1 1124983.PFLCHA0_c24120 0.00096 45.1 COG0322@1|root,COG0322@2|Bacteria,1R268@1224|Proteobacteria,1RZZA@1236|Gammaproteobacteria 1236|Gammaproteobacteria L GIY-YIG type nucleases (URI domain) - - - - - - - - - - - - GIY-YIG k141_9227_1 1479235.KK366039_gene403 5.81e-27 105.0 COG3637@1|root,COG3637@2|Bacteria 2|Bacteria M Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - - - - - - - - - - OMP_b-brl k141_9227_2 1121939.L861_01175 7.11e-13 68.2 COG1893@1|root,COG1893@2|Bacteria,1P0AW@1224|Proteobacteria,1RR49@1236|Gammaproteobacteria,1XJUQ@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 - - - ApbA,ApbA_C k141_19851_1 866895.HBHAL_2460 5.49e-81 249.0 28PQP@1|root,2ZCCM@2|Bacteria,1V1II@1239|Firmicutes,4HGJG@91061|Bacilli 91061|Bacilli S Domain of unknown function (DUF4386) - - - - - - - - - - - - DUF4386 k141_22210_1 218284.CCDN010000001_gene314 2.23e-90 271.0 COG1464@1|root,COG1464@2|Bacteria,1TQAS@1239|Firmicutes,4HCTA@91061|Bacilli,1ZB4Z@1386|Bacillus 91061|Bacilli M Belongs to the nlpA lipoprotein family metQ_3 - - ko:K02073 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - Lipoprotein_9 k141_14970_1 574376.BAMA_23100 1.19e-104 312.0 COG4948@1|root,COG4948@2|Bacteria,1TQMS@1239|Firmicutes,4HCY5@91061|Bacilli,1ZC5Y@1386|Bacillus 91061|Bacilli M Belongs to the mandelate racemase muconate lactonizing enzyme family - - - - - - - - - - - - MR_MLE_C,MR_MLE_N k141_27223_1 156889.Mmc1_1072 1.9e-81 266.0 COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,2TSPQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrA - 5.99.1.3 ko:K02469 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseA_C,DNA_topoisoIV k141_23545_1 1071073.KI530543_gene2971 6.71e-67 211.0 COG0640@1|root,COG0640@2|Bacteria,1V384@1239|Firmicutes,4HGMZ@91061|Bacilli,1ZQK5@1386|Bacillus 91061|Bacilli K Bacterial regulatory protein, arsR family - - - - - - - - - - - - HTH_20,HTH_5 k141_37488_2 717231.Flexsi_0592 1.08e-28 120.0 COG1138@1|root,COG1138@2|Bacteria,2GEUI@200930|Deferribacteres 2|Bacteria O Cytochrome c-type biogenesis protein CcmF C-terminal ccmF GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0018193,GO:0018198,GO:0018378,GO:0019538,GO:0020037,GO:0022607,GO:0031224,GO:0031226,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046906,GO:0048037,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564 - ko:K02198,ko:K04016 - - R05712 RC00176 ko00000,ko02000 9.B.14.1 - - CcmF_C,Cytochrom_C_asm k141_5683_1 1042377.AFPJ01000042_gene1015 2.92e-106 330.0 COG1472@1|root,COG1472@2|Bacteria,1MVAJ@1224|Proteobacteria,1RMQF@1236|Gammaproteobacteria,465G4@72275|Alteromonadaceae 1236|Gammaproteobacteria G Beta-N-acetylhexosaminidase ybbD - 3.2.1.52 ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 M00628 R00022,R05963,R07809,R07810,R10831 RC00049 ko00000,ko00001,ko00002,ko01000 - - - Glyco_hydro_3,Glyco_hydro_3_C k141_32761_1 333138.LQ50_02230 3.72e-32 120.0 COG4974@1|root,COG4974@2|Bacteria,1TR57@1239|Firmicutes,4HJIJ@91061|Bacilli,1ZG26@1386|Bacillus 91061|Bacilli L Phage integrase family xerD3 - - - - - - - - - - - Phage_int_SAM_4,Phage_integrase k141_19852_2 1042377.AFPJ01000023_gene659 3.15e-31 116.0 COG0848@1|root,COG0848@2|Bacteria,1RENY@1224|Proteobacteria,1S3TB@1236|Gammaproteobacteria 1236|Gammaproteobacteria U biopolymer transport protein - - - - - - - - - - - - ExbD k141_9228_2 446469.Sked_00410 4.11e-43 152.0 COG2513@1|root,COG2513@2|Bacteria,2GMQ4@201174|Actinobacteria 201174|Actinobacteria G COG2513 PEP phosphonomutase and related enzymes - - - - - - - - - - - - PEP_mutase k141_12848_1 1122614.JHZF01000004_gene304 6.38e-151 443.0 COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,2TQVI@28211|Alphaproteobacteria,2PDKW@252301|Oceanicola 28211|Alphaproteobacteria J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome fusA - - ko:K02355 - - - - ko00000,ko03012,ko03029 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 k141_6795_1 42565.FP66_07055 5.05e-145 422.0 COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,1RM92@1236|Gammaproteobacteria,1XI53@135619|Oceanospirillales 135619|Oceanospirillales F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates pyrG - 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 - - - CTP_synth_N,GATase k141_24605_2 411467.BACCAP_01048 3.78e-06 47.4 COG1396@1|root,COG1396@2|Bacteria,1UVGV@1239|Firmicutes,25PEW@186801|Clostridia,26CBB@186813|unclassified Clostridiales 186801|Clostridia K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_3 k141_24605_3 1174504.AJTN02000028_gene1761 2.93e-07 52.8 COG1396@1|root,COG1396@2|Bacteria,1UV6T@1239|Firmicutes,4I1D1@91061|Bacilli 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_3 k141_24605_5 66692.ABC2865 1.64e-126 383.0 COG1961@1|root,COG1961@2|Bacteria,1TPUG@1239|Firmicutes,4HB3H@91061|Bacilli,1ZBV3@1386|Bacillus 91061|Bacilli L Recombinase - - - ko:K06400 - - - - ko00000 - - - Recombinase,Resolvase,Zn_ribbon_recom k141_34078_1 1219076.N646_2427 5.69e-72 224.0 COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,1RPTA@1236|Gammaproteobacteria,1XTE0@135623|Vibrionales 135623|Vibrionales M COG0451 Nucleoside-diphosphate-sugar epimerases - - 5.1.3.6 ko:K08679 ko00520,ko01100,map00520,map01100 - R01385 RC00289 ko00000,ko00001,ko01000 - - - Epimerase,GDP_Man_Dehyd k141_34078_2 1116375.VEJY3_01185 2.53e-276 761.0 COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,1RPZC@1236|Gammaproteobacteria,1XUP7@135623|Vibrionales 135623|Vibrionales J exonuclease of the beta-lactamase fold involved in RNA processing - - - ko:K07576 - - - - ko00000 - - - Beta-Casp,Lactamase_B,RMMBL k141_34078_3 1116375.VEJY3_01195 1.04e-171 480.0 COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,1RM8I@1236|Gammaproteobacteria,1XUEE@135623|Vibrionales 135623|Vibrionales G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) tpiA GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01015 RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 - - - TIM k141_9229_1 1453501.JELR01000001_gene3241 3.18e-70 227.0 COG0457@1|root,COG0457@2|Bacteria,1RC07@1224|Proteobacteria,1S36N@1236|Gammaproteobacteria,46864@72275|Alteromonadaceae 1236|Gammaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_8 k141_20892_2 218284.CCDN010000005_gene3323 2.91e-59 187.0 COG4729@1|root,COG4729@2|Bacteria,1VCAR@1239|Firmicutes,4HM9T@91061|Bacilli,1ZE7Y@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF1850) - - - - - - - - - - - - DUF1850 k141_32762_1 42565.FP66_01340 1.1e-98 296.0 COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,1RN4V@1236|Gammaproteobacteria,1XIXJ@135619|Oceanospirillales 135619|Oceanospirillales M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamB - - ko:K17713 - - - - ko00000,ko02000 1.B.33.1 - - PQQ_2,PQQ_3 k141_23546_2 523791.Kkor_1312 9.81e-71 228.0 COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,1RPZC@1236|Gammaproteobacteria,1XHAE@135619|Oceanospirillales 135619|Oceanospirillales J beta-lactamase - - - ko:K07576 - - - - ko00000 - - - Beta-Casp,Lactamase_B,RMMBL k141_25879_1 42565.FP66_12585 8.65e-36 126.0 COG3103@1|root,COG4991@2|Bacteria,1MX7M@1224|Proteobacteria,1RS74@1236|Gammaproteobacteria,1XKNE@135619|Oceanospirillales 135619|Oceanospirillales T Bacterial SH3 domain homologues - - - ko:K07184 - - - - ko00000 - - - SH3_3 k141_19853_1 1042377.AFPJ01000052_gene1537 2.18e-36 138.0 COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,1MVI9@1224|Proteobacteria,1RNB0@1236|Gammaproteobacteria,46617@72275|Alteromonadaceae 1236|Gammaproteobacteria D protein involved in exopolysaccharide biosynthesis - - - ko:K16554,ko:K16692 ko05111,map05111 - - - ko00000,ko00001,ko01000,ko01001,ko02000 8.A.3.1 - - AAA_31,CbiA,GNVR,Wzz k141_19853_2 1266845.Q783_06820 1.83e-16 77.8 COG4464@1|root,COG4464@2|Bacteria,1TQ1T@1239|Firmicutes,4HDZR@91061|Bacilli,27FZQ@186828|Carnobacteriaceae 91061|Bacilli GM Capsular polysaccharide biosynthesis protein ywqE - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - - k141_29284_1 218284.CCDN010000004_gene3064 2.07e-54 171.0 29T6N@1|root,30EDD@2|Bacteria,1UCF1@1239|Firmicutes,4INXD@91061|Bacilli,1ZP2T@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_22213_1 1500301.JQMF01000025_gene6130 3.4e-104 310.0 COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,2TRHS@28211|Alphaproteobacteria,4B99V@82115|Rhizobiaceae 28211|Alphaproteobacteria C Aldo keto reductase - - - - - - - - - - - - Aldo_ket_red k141_5684_1 1502852.FG94_04354 0.000159 43.5 COG0114@1|root,COG0114@2|Bacteria,1MUQI@1224|Proteobacteria,2VHA5@28216|Betaproteobacteria,472U1@75682|Oxalobacteraceae 28216|Betaproteobacteria C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate fumC - 4.2.1.2 ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 M00009,M00011,M00173,M00376 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - - FumaraseC_C,Lyase_1 k141_6797_1 1294265.JCM21738_2670 2.86e-127 391.0 COG3857@1|root,COG3857@2|Bacteria,1TQJW@1239|Firmicutes,4HAY6@91061|Bacilli,1ZC70@1386|Bacillus 91061|Bacilli L ATP-dependent helicase deoxyribonuclease subunit B rexB GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0004527,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.6.4.12 ko:K16899 - - - - ko00000,ko01000,ko03400 - - - Exonuc_V_gamma,PDDEXK_1,UvrD_C k141_35332_2 218284.CCDN010000010_gene4327 5.24e-122 351.0 COG2194@1|root,COG2194@2|Bacteria,1UZ64@1239|Firmicutes,4HFDE@91061|Bacilli,1ZFN5@1386|Bacillus 91061|Bacilli S Involved in the activation of the KinB signaling pathway of sporulation kbaA GO:0008150,GO:0022603,GO:0042173,GO:0043937,GO:0043938,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0065007 - ko:K06349 - - - - ko00000 - - - KbaA k141_9230_1 324057.Pjdr2_0566 3.53e-41 152.0 COG3459@1|root,COG3459@2|Bacteria,1TVMK@1239|Firmicutes,4H9ZP@91061|Bacilli,26RDW@186822|Paenibacillaceae 91061|Bacilli G Cellobiose phosphorylase chvB1 - 2.4.1.20,2.4.1.333 ko:K00702,ko:K13688,ko:K21298 ko00500,ko01100,map00500,map01100 - R00952 RC00049 ko00000,ko00001,ko01000,ko01003 - GH94,GT36,GT84 - Glyco_hydro_36,Glyco_transf_36 k141_9230_2 1341151.ASZU01000016_gene779 4.29e-41 139.0 COG3663@1|root,COG3663@2|Bacteria,1V3X9@1239|Firmicutes,4HHMZ@91061|Bacilli 91061|Bacilli L COG3663 G T U mismatch-specific DNA glycosylase - - 3.2.2.28 ko:K03649 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG k141_14134_1 218284.CCDN010000001_gene1634 5.31e-06 44.7 2DF66@1|root,2ZQMC@2|Bacteria,1W5KW@1239|Firmicutes,4I1NF@91061|Bacilli 91061|Bacilli S Fur-regulated basic protein A - - - - - - - - - - - - Fur_reg_FbpA k141_32763_1 1294265.JCM21738_1731 1.63e-108 342.0 COG1629@1|root,COG4412@1|root,COG1629@2|Bacteria,COG4412@2|Bacteria 2|Bacteria S peptidase activity, acting on L-amino acid peptides - - 3.2.1.18,3.2.1.52 ko:K01186,ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00600,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00600,map00603,map00604,map01100,map04142 M00079 R00022,R04018,R06004,R11316 RC00028,RC00049,RC00077 ko00000,ko00001,ko00002,ko01000,ko02042,ko03110 - GH20,GH33 - CarbopepD_reg_2,Endonuclease_1,Erythro_esteras,F5_F8_type_C,FIVAR,Glyco_hydro_20,Glyco_hydro_20b,LTD,Laminin_G_3,OMP_b-brl_3,Sialidase_penC k141_18821_3 1610833.A0A0E3XB76_9CAUD 6.17e-24 96.3 4QB6J@10239|Viruses,4QQ7W@28883|Caudovirales 28883|Caudovirales S dCTP diphosphatase activity - - - - - - - - - - - - - k141_28062_2 218284.CCDN010000002_gene2362 1.57e-63 196.0 2E3CY@1|root,32YC7@2|Bacteria,1VGK5@1239|Firmicutes,4HPSI@91061|Bacilli,1ZJEC@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_28062_3 218284.CCDN010000002_gene2361 1.48e-110 321.0 COG1607@1|root,COG1607@2|Bacteria,1V3S2@1239|Firmicutes,4HJ0Z@91061|Bacilli,1ZGQ9@1386|Bacillus 91061|Bacilli I Acyl-CoA hydrolase ykhA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0047617,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 - - - - - - - - - - 4HBT k141_28062_4 218284.CCDN010000002_gene2360 2.34e-59 191.0 COG0583@1|root,COG0583@2|Bacteria,1TQ6Y@1239|Firmicutes,4HB94@91061|Bacilli,1ZBXV@1386|Bacillus 91061|Bacilli K Transcriptional regulator ywbI GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:1901363,GO:1990837 - - - - - - - - - - HTH_1,LysR_substrate k141_36423_2 1279017.AQYJ01000020_gene1360 1.53e-141 417.0 COG0457@1|root,COG0457@2|Bacteria,1N8R8@1224|Proteobacteria,1SBTP@1236|Gammaproteobacteria,46AT1@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0457 FOG TPR repeat - - - - - - - - - - - - TPR_16 k141_7075_1 1453501.JELR01000001_gene2618 2.92e-100 307.0 COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,1RMFZ@1236|Gammaproteobacteria,464A9@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) mltD GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008932,GO:0008933,GO:0009893,GO:0016020,GO:0016740,GO:0016757,GO:0019222,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043085,GO:0044093,GO:0044464,GO:0048518,GO:0050789,GO:0050790,GO:0051341,GO:0051353,GO:0061783,GO:0065007,GO:0065009 - ko:K08307 - - - - ko00000,ko01000,ko01011 - - - LysM,SLT k141_31574_1 1174504.AJTN02000193_gene4132 2.4e-68 211.0 COG0673@1|root,COG0673@2|Bacteria,1UZRV@1239|Firmicutes,4HEWB@91061|Bacilli,1ZE5A@1386|Bacillus 91061|Bacilli S dehydrogenases and related proteins ysjB - - ko:K03810 - - - - ko00000 - - - GFO_IDH_MocA k141_20999_1 406124.ACPC01000008_gene1675 5.86e-95 286.0 COG1349@1|root,COG1349@2|Bacteria,1V27B@1239|Firmicutes,4HGDW@91061|Bacilli,1ZFQZ@1386|Bacillus 91061|Bacilli K DeoR C terminal sensor domain - - - - - - - - - - - - DeoRC,HTH_DeoR k141_1985_1 42565.FP66_08715 1.63e-107 330.0 COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,1RMH7@1236|Gammaproteobacteria,1XIBB@135619|Oceanospirillales 135619|Oceanospirillales S C4-dicarboxylate ABC transporter permease - - - - - - - - - - - - DctM k141_32968_1 218284.CCDN010000007_gene3910 1.9e-113 336.0 COG2031@1|root,COG2031@2|Bacteria,1TPCQ@1239|Firmicutes,4HAQF@91061|Bacilli,1ZECR@1386|Bacillus 91061|Bacilli I Short chain fatty acid transporter atoE - - ko:K02106 ko02020,map02020 - - - ko00000,ko00001 2.A.73.1 - - SCFA_trans k141_16370_1 324602.Caur_0928 3.34e-30 118.0 COG0325@1|root,COG0325@2|Bacteria,2G6F1@200795|Chloroflexi,375I2@32061|Chloroflexia 32061|Chloroflexia S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis - - - ko:K06997 - - - - ko00000 - - - Ala_racemase_N k141_22455_1 1116375.VEJY3_14735 4.63e-150 427.0 COG0111@1|root,COG0111@2|Bacteria,1MW1U@1224|Proteobacteria,1RRQE@1236|Gammaproteobacteria,1XT3B@135623|Vibrionales 135623|Vibrionales EH COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases - - - - - - - - - - - - 2-Hacid_dh_C k141_22455_2 1116375.VEJY3_14730 8.53e-134 379.0 COG3068@1|root,COG3068@2|Bacteria,1MWSN@1224|Proteobacteria,1RQDG@1236|Gammaproteobacteria,1XT50@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria - - - ko:K09891 - - - - ko00000 - - - DUF416 k141_22455_3 1116375.VEJY3_14725 2.17e-233 646.0 COG1253@1|root,COG1253@2|Bacteria,1MWT3@1224|Proteobacteria,1RQBC@1236|Gammaproteobacteria,1XT75@135623|Vibrionales 135623|Vibrionales S COG1253 Hemolysins and related proteins containing CBS domains - - - - - - - - - - - - CBS,DUF21 k141_22455_4 1280001.BAOA01000066_gene2720 1.32e-55 173.0 COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,1S8VH@1236|Gammaproteobacteria,1XXVI@135623|Vibrionales 135623|Vibrionales L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions hupA GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0005829,GO:0006323,GO:0006996,GO:0008150,GO:0009889,GO:0009987,GO:0010556,GO:0016043,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0051276,GO:0060255,GO:0065007,GO:0071103,GO:0071840,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2001141 - ko:K05787 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding k141_22455_5 1116375.VEJY3_14715 2.04e-48 160.0 28HWS@1|root,2Z82N@2|Bacteria,1QFI0@1224|Proteobacteria,1RPY5@1236|Gammaproteobacteria,1XTX1@135623|Vibrionales 135623|Vibrionales M Protein of unknown function (DUF1481) atpB - - - - - - - - - - - DUF1481 k141_5808_1 1453501.JELR01000001_gene3152 1.87e-140 410.0 COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,1RMI7@1236|Gammaproteobacteria,464RZ@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family bepF - - ko:K18298,ko:K19586 - M00641,M00767 - - ko00000,ko00002,ko01504,ko02000 2.A.6.2.47,8.A.1 - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 k141_35534_1 1116375.VEJY3_18296 8.73e-102 315.0 COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,1RNKA@1236|Gammaproteobacteria 1236|Gammaproteobacteria H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses nadE - 6.3.1.5,6.3.5.1 ko:K01916,ko:K01950 ko00760,ko01100,map00760,map01100 M00115 R00189,R00257 RC00010,RC00100 ko00000,ko00001,ko00002,ko01000 - - - CN_hydrolase,NAD_synthase k141_28063_1 218284.CCDN010000001_gene1720 1.59e-100 297.0 COG3340@1|root,COG3340@2|Bacteria,1V7ZB@1239|Firmicutes,4HIGE@91061|Bacilli,1ZGQX@1386|Bacillus 91061|Bacilli E Belongs to the peptidase S51 family - - 3.4.13.21 ko:K05995 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S51 k141_29446_2 218284.CCDN010000001_gene947 1.66e-93 280.0 COG1752@1|root,COG1752@2|Bacteria,1TRJW@1239|Firmicutes,4HB8J@91061|Bacilli,1ZC13@1386|Bacillus 91061|Bacilli S esterase of the alpha-beta hydrolase superfamily yqhO GO:0003674,GO:0003824,GO:0016787 - ko:K07001 - - - - ko00000 - - - Patatin k141_7076_1 218284.CCDN010000007_gene3802 3.07e-59 188.0 COG1811@1|root,COG1811@2|Bacteria,1UH19@1239|Firmicutes,4HB4E@91061|Bacilli,1ZBSK@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF554) ydfK - - ko:K07150 - - - - ko00000 - - - DUF554 k141_7076_2 218284.CCDN010000007_gene3801 1.14e-125 362.0 COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,4H9TB@91061|Bacilli,1ZBDT@1386|Bacillus 91061|Bacilli K Belongs to the ParB family spo0J GO:0005575,GO:0005622,GO:0005623,GO:0007059,GO:0008150,GO:0009295,GO:0009987,GO:0022603,GO:0042173,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0043937,GO:0043938,GO:0044424,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0065007 - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - HTH_3,KorB,ParBc k141_5809_1 1294265.JCM21738_4733 7.76e-94 290.0 COG2199@1|root,COG2203@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,1TQ2X@1239|Firmicutes,4HA6T@91061|Bacilli,1ZCE7@1386|Bacillus 91061|Bacilli T COG2199 FOG GGDEF domain ytrP - - - - - - - - - - - GAF_2,GAF_3,GGDEF k141_3252_1 218284.CCDN010000002_gene1996 1.36e-53 176.0 COG1470@1|root,COG1470@2|Bacteria,1TRGE@1239|Firmicutes,4HBPI@91061|Bacilli,1ZB6W@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3048) C-terminal domain yerB - - - - - - - - - - - DUF3048,DUF3048_C k141_5810_1 1078085.HMPREF1210_00665 2.39e-90 295.0 COG1409@1|root,COG4632@1|root,COG1409@2|Bacteria,COG4632@2|Bacteria,1UWQ2@1239|Firmicutes,4I2G2@91061|Bacilli,26G7J@186818|Planococcaceae 91061|Bacilli G Purple acid Phosphatase, N-terminal domain - - - - - - - - - - - - Metallophos,Pur_ac_phosph_N k141_7077_2 445335.CBN_2821 3.74e-05 50.1 COG2068@1|root,COG2068@2|Bacteria,1VCCX@1239|Firmicutes,25CVA@186801|Clostridia,36X1A@31979|Clostridiaceae 186801|Clostridia S Guanylyl transferase CofC like - - 2.7.7.76 ko:K07141 ko00790,map00790 - R11582 - ko00000,ko00001,ko01000 - - - NTP_transf_3 k141_21001_1 218284.CCDN010000001_gene1408 4.89e-58 189.0 COG4086@1|root,COG4086@2|Bacteria,1TR2I@1239|Firmicutes,4HBVZ@91061|Bacilli,1ZD5H@1386|Bacillus 91061|Bacilli S Secreted protein ypuA - - - - - - - - - - - DUF1002 k141_9436_3 1453501.JELR01000001_gene2184 1.39e-27 101.0 2CDU3@1|root,33AS4@2|Bacteria,1NGWQ@1224|Proteobacteria,1SGBH@1236|Gammaproteobacteria,468VZ@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF2970) - - - - - - - - - - - - DUF2970 k141_9436_4 1453501.JELR01000001_gene2185 0.0 2091.0 COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,1RMYD@1236|Gammaproteobacteria,4643G@72275|Alteromonadaceae 1236|Gammaproteobacteria E Methionine synthase metH GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 ko:K00548 ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230 M00017 R00946,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - iECO103_1326.ECO103_4764,iECUMN_1333.ECUMN_4545 B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans k141_9436_5 1453501.JELR01000001_gene2187 1.2e-131 374.0 COG0694@1|root,COG0694@2|Bacteria,1MU8Y@1224|Proteobacteria,1RN7J@1236|Gammaproteobacteria,465AK@72275|Alteromonadaceae 1236|Gammaproteobacteria C Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins nfuA GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010106,GO:0010467,GO:0015976,GO:0016043,GO:0016226,GO:0019538,GO:0019725,GO:0022607,GO:0030003,GO:0031163,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042592,GO:0042594,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0050896,GO:0051186,GO:0051536,GO:0051539,GO:0051540,GO:0051604,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071496,GO:0071704,GO:0071840,GO:0097428,GO:0098771,GO:1901564 - ko:K07400 - - - - ko00000 - - - Fe-S_biosyn,NifU k141_9436_6 1042377.AFPJ01000007_gene1872 8.95e-87 265.0 arCOG10317@1|root,2Z7VW@2|Bacteria,1RGUS@1224|Proteobacteria,1S5VW@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_9436_7 1121104.AQXH01000002_gene772 1.07e-83 263.0 COG2342@1|root,COG2342@2|Bacteria,4NH17@976|Bacteroidetes 976|Bacteroidetes G Glycoside-hydrolase family GH114 - - 6.1.1.16 ko:K01884 ko00970,map00970 M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Glyco_hydro_114 k141_9436_8 1042377.AFPJ01000009_gene226 0.0 1108.0 COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,1RR1B@1236|Gammaproteobacteria,46421@72275|Alteromonadaceae 1236|Gammaproteobacteria L ATP-dependent helicase HrpB hrpB - 3.6.4.13 ko:K03579 - - - - ko00000,ko01000 - - - DEAD,HA2,Helicase_C,HrpB_C k141_22458_1 1266909.AUAG01000025_gene1862 5.53e-27 110.0 COG1295@1|root,COG1959@1|root,COG1295@2|Bacteria,COG1959@2|Bacteria,1QICW@1224|Proteobacteria,1RMKI@1236|Gammaproteobacteria,1WWKW@135613|Chromatiales 135613|Chromatiales K ribonuclease BN - - - ko:K07058 - - - - ko00000 - - - Rrf2,Virul_fac_BrkB k141_4469_1 1121938.AUDY01000014_gene3568 1.37e-14 69.3 COG1734@1|root,COG1734@2|Bacteria,1VI7F@1239|Firmicutes,4HNWS@91061|Bacilli,3NF8F@45667|Halobacillus 91061|Bacilli T Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters yocK_1 - - - - - - - - - - - - k141_4469_2 981383.AEWH01000047_gene569 1.26e-55 176.0 COG2050@1|root,COG2050@2|Bacteria,1V7G2@1239|Firmicutes,4HIIA@91061|Bacilli 91061|Bacilli Q protein possibly involved in aromatic compounds catabolism yuxO - - - - - - - - - - - 4HBT k141_4469_3 240302.BN982_03749 2.78e-10 59.7 COG1575@1|root,COG1575@2|Bacteria,1TSZV@1239|Firmicutes,4HA68@91061|Bacilli,3NEH3@45667|Halobacillus 91061|Bacilli H Belongs to the MenA family. Type 1 subfamily menA - 2.5.1.74 ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R05617,R06858,R10757 RC02935,RC02936,RC03264 ko00000,ko00001,ko00002,ko01000,ko01006 - - - UbiA k141_20082_1 218284.CCDN010000002_gene2235 5.71e-30 109.0 COG4980@1|root,COG4980@2|Bacteria,1VGY5@1239|Firmicutes,4HPNI@91061|Bacilli,1ZIVN@1386|Bacillus 91061|Bacilli S gas vesicle protein yfkI - - - - - - - - - - - - k141_20082_2 649639.Bcell_1770 2.51e-58 186.0 COG0394@1|root,COG0394@2|Bacteria,1V6SG@1239|Firmicutes,4HIZN@91061|Bacilli,1ZG7W@1386|Bacillus 91061|Bacilli T Belongs to the low molecular weight phosphotyrosine protein phosphatase family yfkJ - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - LMWPc k141_20082_3 218284.CCDN010000002_gene2234 9.68e-46 148.0 COG4840@1|root,COG4840@2|Bacteria,1VEYR@1239|Firmicutes,4HNKK@91061|Bacilli,1ZJ0U@1386|Bacillus 91061|Bacilli S Belongs to the UPF0435 family yfkK - - - - - - - - - - - DUF1128 k141_24775_1 1116375.VEJY3_06730 1.16e-104 306.0 COG4126@1|root,COG4126@2|Bacteria,1MVNB@1224|Proteobacteria,1RQXU@1236|Gammaproteobacteria,1XXDY@135623|Vibrionales 135623|Vibrionales E Asp/Glu/Hydantoin racemase - - 5.1.99.3 ko:K16841 ko00230,ko01120,map00230,map01120 - R03925 RC01027 ko00000,ko00001,ko01000 - - - Asp_Glu_race k141_24775_3 1116375.VEJY3_06740 0.0 897.0 COG1953@1|root,COG1953@2|Bacteria,1MV18@1224|Proteobacteria,1RMZU@1236|Gammaproteobacteria,1XY89@135623|Vibrionales 135623|Vibrionales FH Permease for cytosine/purines, uracil, thiamine, allantoin - - - ko:K03457 - - - - ko00000 2.A.39 - - Transp_cyt_pur k141_24775_4 1116375.VEJY3_06745 1.08e-251 694.0 COG0154@1|root,COG0154@2|Bacteria,1MU51@1224|Proteobacteria,1RR6N@1236|Gammaproteobacteria,1XY2Y@135623|Vibrionales 135623|Vibrionales J Amidase - - 3.5.1.4 ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 - R02540,R03096,R03180,R03909,R05551,R05590 RC00010,RC00100,RC00950,RC01025 ko00000,ko00001,ko01000 - - - Amidase k141_24775_5 1116375.VEJY3_06750 0.0 967.0 COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,1XWE1@135623|Vibrionales 135623|Vibrionales E Gamma-glutamyltranspeptidase - - 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept k141_24775_6 1116375.VEJY3_06755 2.79e-294 803.0 COG0075@1|root,COG0075@2|Bacteria,1MWHJ@1224|Proteobacteria,1RMNR@1236|Gammaproteobacteria,1XWNK@135623|Vibrionales 135623|Vibrionales E Aminotransferase class-V - - 2.6.1.112 ko:K00839 ko00230,map00230 - R10908 RC00018,RC03305 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_5 k141_24775_7 1116375.VEJY3_06760 2.58e-59 194.0 COG0624@1|root,COG0624@2|Bacteria,1MVUX@1224|Proteobacteria,1RPPD@1236|Gammaproteobacteria,1XV99@135623|Vibrionales 135623|Vibrionales E Peptidase family M20/M25/M40 - - 3.5.3.9 ko:K02083 ko00230,ko01120,map00230,map01120 - R02423 RC00064 ko00000,ko00001,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 k141_26104_1 880073.Calab_1134 1.5e-45 170.0 COG2091@1|root,COG2091@2|Bacteria,2NQGR@2323|unclassified Bacteria 2|Bacteria H lysine biosynthetic process via aminoadipic acid - - - - - - - - - - - - CBM9_1 k141_21034_2 218284.CCDN010000001_gene1009 7.2e-55 175.0 COG0406@1|root,COG0406@2|Bacteria,1V7F8@1239|Firmicutes,4HIR1@91061|Bacilli,1ZHAP@1386|Bacillus 91061|Bacilli G Phosphoglycerate mutase gpmA1 - 5.4.2.11 ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - His_Phos_1 k141_29475_1 1042377.AFPJ01000053_gene1508 1.67e-45 162.0 COG0457@1|root,COG0457@2|Bacteria,1R9C8@1224|Proteobacteria,1RY5F@1236|Gammaproteobacteria 1236|Gammaproteobacteria S COG0457 FOG TPR repeat - - - - - - - - - - - - TPR_16,TPR_19,TPR_2,TPR_8,Transglut_core k141_29475_3 1415754.JQMK01000002_gene2275 3.02e-113 335.0 28IWY@1|root,2Z8V1@2|Bacteria,1R9PZ@1224|Proteobacteria,1SGUD@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_29475_4 1453501.JELR01000002_gene763 1.85e-308 867.0 COG0834@1|root,COG4623@1|root,COG0834@2|Bacteria,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,1RM8W@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella - GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - ko:K18691 - - - - ko00000,ko01000,ko01011 - - - SBP_bac_3,SLT k141_29475_6 426716.JOAJ01000001_gene1730 1.18e-102 309.0 COG0596@1|root,COG0596@2|Bacteria,2I9FN@201174|Actinobacteria,4G8Z4@85025|Nocardiaceae 201174|Actinobacteria S Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 k141_29475_7 857087.Metme_1811 2.35e-43 143.0 2C82G@1|root,32RK9@2|Bacteria,1MZV5@1224|Proteobacteria,1SAWR@1236|Gammaproteobacteria,1XFGD@135618|Methylococcales 135618|Methylococcales S Protein of unknown function (DUF4242) - - - - - - - - - - - - DUF4242 k141_29475_8 1453501.JELR01000002_gene866 3.09e-54 187.0 COG0457@1|root,COG0457@2|Bacteria,1NAJI@1224|Proteobacteria 1224|Proteobacteria T ATPase activity - - - - - - - - - - - - DUF1570 k141_1119_1 1283337.B0ZSG9_BPHA1 2.11e-60 191.0 4QGAP@10239|Viruses,4QWU3@35237|dsDNA viruses no RNA stage,4QQUA@28883|Caudovirales,4QIA5@10662|Myoviridae 10662|Myoviridae S Phage tail tube protein FII - - - - - - - - - - - - - k141_1119_2 1283337.B0ZSG8_BPHA1 7.97e-181 514.0 4QAZ6@10239|Viruses,4QUU8@35237|dsDNA viruses no RNA stage,4QPHV@28883|Caudovirales,4QI4H@10662|Myoviridae 10662|Myoviridae S Phage tail sheath protein - GO:0005575,GO:0019012,GO:0044423,GO:0098015,GO:0098027 - - - - - - - - - - - k141_7127_1 218284.CCDN010000001_gene971 3.37e-173 498.0 COG1154@1|root,COG1154@2|Bacteria,1TP37@1239|Firmicutes,4H9QW@91061|Bacilli,1ZBHF@1386|Bacillus 91061|Bacilli H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) dxs - 2.2.1.7 ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 M00096 R05636 RC00032 ko00000,ko00001,ko00002,ko01000 - - - DXP_synthase_N,Transket_pyr,Transketolase_C k141_9480_1 218284.CCDN010000001_gene47 3.01e-209 586.0 COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,4HAK8@91061|Bacilli,1ZD3R@1386|Bacillus 91061|Bacilli H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine coaBC - 4.1.1.36,6.3.2.5 ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 - - - DFP,Flavoprotein k141_9480_3 218284.CCDN010000001_gene49 1.82e-128 367.0 COG0194@1|root,COG0194@2|Bacteria,1TP0M@1239|Firmicutes,4HAYW@91061|Bacilli,1ZBZI@1386|Bacillus 91061|Bacilli F Essential for recycling GMP and indirectly, cGMP gmk GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU15680 Guanylate_kin k141_16408_2 218284.CCDN010000001_gene1311 7.57e-48 155.0 COG2076@1|root,COG2076@2|Bacteria,1VAQQ@1239|Firmicutes,4HKMP@91061|Bacilli,1ZHZ0@1386|Bacillus 91061|Bacilli P Multidrug resistance protein - - - ko:K11741 - - - - ko00000,ko02000 2.A.7.1 - - Multi_Drug_Res k141_15139_1 935836.JAEL01000077_gene183 5.75e-107 324.0 COG0635@1|root,COG0635@2|Bacteria,1TREM@1239|Firmicutes,4HC2D@91061|Bacilli,1ZCRB@1386|Bacillus 91061|Bacilli H coproporphyrinogen III oxidase hemZ - - - - - - - - - - - Radical_SAM k141_3276_1 218284.CCDN010000005_gene3223 4.93e-139 407.0 COG2206@1|root,COG2206@2|Bacteria,1UZN2@1239|Firmicutes,4HIY3@91061|Bacilli,1ZS2G@1386|Bacillus 91061|Bacilli T HD domain - - - - - - - - - - - - HD,HD_5 k141_37678_2 218284.CCDN010000001_gene770 6.07e-110 322.0 COG0648@1|root,COG0648@2|Bacteria,1TP1D@1239|Firmicutes,4HB4F@91061|Bacilli,1ZBYQ@1386|Bacillus 91061|Bacilli L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin nfo GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.1.21.2 ko:K01151 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - AP_endonuc_2 k141_29477_1 1177179.A11A3_11838 3.84e-63 201.0 COG0745@1|root,COG0745@2|Bacteria,1Q2S0@1224|Proteobacteria,1RQZZ@1236|Gammaproteobacteria,1XHWU@135619|Oceanospirillales 135619|Oceanospirillales T consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain rstA - - ko:K07661 ko02020,map02020 M00446 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C k141_17479_2 447909.A6M989_9VIRU 3.18e-42 145.0 4QAKE@10239|Viruses 10239|Viruses S endonuclease activity - - - - - - - - - - - - - k141_2024_2 1238182.C882_3025 1.29e-66 219.0 COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,1MUDN@1224|Proteobacteria,2U247@28211|Alphaproteobacteria 28211|Alphaproteobacteria P COG0491 Zn-dependent hydrolases, including glyoxylases - - - - - - - - - - - - Lactamase_B,Rhodanese k141_20084_1 1294265.JCM21738_3688 3.29e-06 47.4 COG0711@1|root,COG0711@2|Bacteria,1VB85@1239|Firmicutes,4HM64@91061|Bacilli,1ZGHN@1386|Bacillus 91061|Bacilli C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) atpF - - ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - iYO844.BSU36850 ATP-synt_B k141_20084_3 1294265.JCM21738_3686 9.03e-22 90.5 COG0356@1|root,COG0356@2|Bacteria,1TQIT@1239|Firmicutes,4H9NV@91061|Bacilli,1ZB02@1386|Bacillus 91061|Bacilli C it plays a direct role in the translocation of protons across the membrane atpB GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 - - ATP-synt_A k141_16409_1 1121374.KB891575_gene802 3e-78 238.0 COG1917@1|root,COG1917@2|Bacteria,1N3S2@1224|Proteobacteria 1224|Proteobacteria S Aspartyl/Asparaginyl beta-hydroxylase - - - - - - - - - - - - Asp_Arg_Hydrox k141_1120_1 886377.Murru_2961 1.46e-37 139.0 COG0534@1|root,COG0534@2|Bacteria,4NDUF@976|Bacteroidetes,1HX7D@117743|Flavobacteriia 976|Bacteroidetes V Multidrug transporter MatE - - - ko:K03327 - - - - ko00000,ko02000 2.A.66.1 - - MatE k141_30427_1 1298860.AUEM01000007_gene1966 4.02e-46 158.0 COG5361@1|root,COG5361@2|Bacteria,2GKTA@201174|Actinobacteria,4FMDK@85023|Microbacteriaceae 201174|Actinobacteria S Protein of unknown function (DUF1214) - - - - - - - - - - - - DUF1214,DUF1254 k141_4472_1 218284.CCDN010000002_gene2168 2.59e-79 253.0 COG1164@1|root,COG1164@2|Bacteria,1TQ5W@1239|Firmicutes,4HAN9@91061|Bacilli,1ZCRR@1386|Bacillus 91061|Bacilli E COG1164 Oligoendopeptidase F pepF2 - - - - - - - - - - - Peptidase_M3,Peptidase_M3_N k141_21036_1 1385514.N782_00960 2.44e-19 84.7 COG3546@1|root,COG3546@2|Bacteria,1TP0F@1239|Firmicutes,4HBA9@91061|Bacilli,2YA1V@289201|Pontibacillus 91061|Bacilli P Manganese catalase - - - - - - - - - - - - Mn_catalase k141_21036_2 1385513.N780_13270 2.04e-22 88.6 2EFV8@1|root,335FH@2|Bacteria,1VHPC@1239|Firmicutes,4HNKU@91061|Bacilli,2YAX3@289201|Pontibacillus 91061|Bacilli S Protein of unknown function (DUF2642) - - - - - - - - - - - - DUF2642 k141_29478_1 218284.CCDN010000008_gene4193 7.45e-147 417.0 COG0115@1|root,COG0115@2|Bacteria,1TPY2@1239|Firmicutes,4HAWW@91061|Bacilli,1ZBVX@1386|Bacillus 91061|Bacilli E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction dat GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016769,GO:0019478,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0046416,GO:0046437,GO:0047810,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.6.1.21 ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 - R01148,R01582,R02459,R02851,R02924,R05053 RC00006,RC00008,RC00025 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_4 k141_28101_2 1453501.JELR01000001_gene2971 1.64e-141 406.0 COG1090@1|root,COG1090@2|Bacteria,1MUB4@1224|Proteobacteria,1RN6A@1236|Gammaproteobacteria,465A2@72275|Alteromonadaceae 1236|Gammaproteobacteria S nucleoside-diphosphate sugar epimerase yfcH - - ko:K07071 - - - - ko00000 - - - DUF1731,Epimerase k141_10504_1 1453501.JELR01000001_gene2961 6.02e-37 136.0 COG0204@1|root,COG3176@1|root,COG0204@2|Bacteria,COG3176@2|Bacteria,1MWIM@1224|Proteobacteria,1RQD4@1236|Gammaproteobacteria,464MD@72275|Alteromonadaceae 1236|Gammaproteobacteria I Acyltransferase - - - - - - - - - - - - Acetyltransf_5,Acyltransferase k141_1121_1 1042377.AFPJ01000024_gene736 1.98e-83 251.0 COG3945@1|root,COG3945@2|Bacteria 2|Bacteria P hemerythrin HHE cation binding domain VP0501 - - - - - - - - - - - Hemerythrin k141_35561_1 1116375.VEJY3_06360 9.26e-158 459.0 COG1164@1|root,COG1164@2|Bacteria,1MXAC@1224|Proteobacteria,1S6M5@1236|Gammaproteobacteria,1XVUU@135623|Vibrionales 135623|Vibrionales E COG1164 Oligoendopeptidase F - - - ko:K08602 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M3,Peptidase_M3_N k141_35561_2 1116375.VEJY3_06330 2.48e-136 389.0 COG0702@1|root,COG0702@2|Bacteria,1MZG7@1224|Proteobacteria,1SB4B@1236|Gammaproteobacteria,1XUJ1@135623|Vibrionales 135623|Vibrionales GM Nucleoside-diphosphate-sugar epimerases - - - - - - - - - - - - HIM1,NAD_binding_10 k141_35561_3 1116375.VEJY3_06325 1.28e-274 758.0 COG1823@1|root,COG1823@2|Bacteria,1R3F8@1224|Proteobacteria,1RMHV@1236|Gammaproteobacteria,1XUK9@135623|Vibrionales 135623|Vibrionales U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - ko:K06956 - - - - ko00000 - - - SDF k141_35561_4 1219076.N646_0801 6.4e-71 214.0 COG5507@1|root,COG5507@2|Bacteria,1RHC1@1224|Proteobacteria,1S6KT@1236|Gammaproteobacteria,1XYTC@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF1428) - - - - - - - - - - - - DUF1428 k141_9482_1 622312.ROSEINA2194_03803 4.08e-08 54.3 COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,247P5@186801|Clostridia 186801|Clostridia H Belongs to the formate--tetrahydrofolate ligase family fhs - 6.3.4.3 ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R00943 RC00026,RC00111 ko00000,ko00001,ko00002,ko01000 - - - FTHFS k141_9482_2 218284.CCDN010000001_gene1186 2.46e-102 302.0 COG0500@1|root,COG2226@2|Bacteria,1U9IT@1239|Firmicutes,4HDV5@91061|Bacilli,1ZC30@1386|Bacillus 91061|Bacilli Q Methionine biosynthesis protein MetW rebM - - - - - - - - - - - Methyltransf_11 k141_26107_1 1211035.CD30_18560 3.06e-68 209.0 COG1495@1|root,COG1495@2|Bacteria,1V79S@1239|Firmicutes,4HIKP@91061|Bacilli,3IYJ5@400634|Lysinibacillus 91061|Bacilli C Required for disulfide bond formation in some proteins bdbC - - ko:K03611 - - - - ko00000,ko03110 5.A.2.1 - - DsbB k141_26107_2 1196031.ALEG01000029_gene3813 3.91e-12 65.1 COG1651@1|root,COG1651@2|Bacteria,1V6IC@1239|Firmicutes,4HKJU@91061|Bacilli,1ZE03@1386|Bacillus 91061|Bacilli O Thioredoxin bdbD - - - - - - - - - - - Thioredoxin_4 k141_2025_2 1333507.AUTQ01000207_gene1541 1.12e-38 136.0 COG0454@1|root,COG0456@2|Bacteria,1RIU4@1224|Proteobacteria,1S6NR@1236|Gammaproteobacteria,2Q30F@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria K FR47-like protein - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10 k141_21037_1 1121929.KB898666_gene2558 1.48e-57 201.0 COG0553@1|root,COG4715@1|root,COG0553@2|Bacteria,COG4715@2|Bacteria,1TPFZ@1239|Firmicutes,4HAIF@91061|Bacilli,471G0@74385|Gracilibacillus 91061|Bacilli KL Bacterial SNF2 helicase associated snf - - - - - - - - - - - Helicase_C,SNF2_N,SNF2_assoc,SWIM k141_15140_1 218284.CCDN010000005_gene3336 2.17e-104 315.0 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli,1ZAXK@1386|Bacillus 91061|Bacilli C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively yfmT GO:0003674,GO:0003824,GO:0004029,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0018479,GO:0055114 1.2.1.3,1.2.1.67 ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R05699,R06366,R08146 RC00047,RC00071,RC00075,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU38830 Aldedh k141_15140_2 218284.CCDN010000005_gene3337 4.16e-08 53.1 COG4221@1|root,COG4221@2|Bacteria,1TRHF@1239|Firmicutes,4HBXH@91061|Bacilli,1ZQ69@1386|Bacillus 91061|Bacilli S Enoyl-(Acyl carrier protein) reductase - - - - - - - - - - - - adh_short k141_1625_1 396588.Tgr7_2336 9.57e-51 164.0 COG0250@1|root,COG0250@2|Bacteria,1MU14@1224|Proteobacteria,1RMW0@1236|Gammaproteobacteria,1WWG3@135613|Chromatiales 135613|Chromatiales K Participates in transcription elongation, termination and antitermination nusG - - ko:K02601 - - - - ko00000,ko03009,ko03021 - - - KOW,NusG k141_1625_2 1123256.KB907960_gene481 1.25e-17 78.2 COG0690@1|root,COG0690@2|Bacteria,1RDI9@1224|Proteobacteria,1S3PA@1236|Gammaproteobacteria,1X7DX@135614|Xanthomonadales 135614|Xanthomonadales U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation secE - - ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecE k141_5327_1 218284.CCDN010000005_gene3357 9.28e-61 202.0 2DPC7@1|root,331GW@2|Bacteria,1VF6Y@1239|Firmicutes,4HPGW@91061|Bacilli,1ZHDU@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_37270_1 1042377.AFPJ01000025_gene597 1.87e-124 372.0 COG0365@1|root,COG0365@2|Bacteria,1MUX7@1224|Proteobacteria,1RPGT@1236|Gammaproteobacteria,465WE@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases acsA - 6.2.1.16 ko:K01907 ko00280,ko00650,map00280,map00650 - R01357 RC00004,RC00014 ko00000,ko00001,ko01000,ko01004 - - - ACAS_N,AMP-binding,AMP-binding_C k141_19541_1 218284.CCDN010000006_gene3562 2.37e-66 214.0 COG0477@1|root,COG2814@2|Bacteria,1TQHD@1239|Firmicutes,4HBCZ@91061|Bacilli,1ZAUW@1386|Bacillus 91061|Bacilli EGP COG0477 Permeases of the major facilitator superfamily ywoG GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - - - - - - - - - - MFS_1,MFS_1_like,MFS_2,Sugar_tr k141_2829_1 218284.CCDN010000002_gene2855 1.12e-174 529.0 COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1TQ0B@1239|Firmicutes,4HA4G@91061|Bacilli,1ZBFF@1386|Bacillus 91061|Bacilli E glutamate synthase gltA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14,1.4.7.1 ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 - R00021,R00093,R00114,R00248,R10086 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - GATase_2,GXGXG,Glu_syn_central,Glu_synthase k141_14690_1 1121921.KB898708_gene1642 1.75e-83 273.0 COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,1T4K6@1236|Gammaproteobacteria 1236|Gammaproteobacteria KLT Sulfatase-modifying factor enzyme 1 ppkA - 2.7.11.1 ko:K11912 ko02025,ko03070,map02025,map03070 - - - ko00000,ko00001,ko01000,ko01001,ko02044 - - - FGE-sulfatase,PEGA,Pkinase k141_14690_3 1279017.AQYJ01000025_gene753 0.0 1141.0 COG0116@1|root,COG1092@1|root,COG0116@2|Bacteria,COG1092@2|Bacteria,1MUQM@1224|Proteobacteria,1RNMH@1236|Gammaproteobacteria,4657X@72275|Alteromonadaceae 1236|Gammaproteobacteria J Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA rlmL GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.173,2.1.1.264 ko:K12297 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - Methyltrans_SAM,THUMP,UPF0020 k141_27694_1 218284.CCDN010000002_gene2944 6.1e-162 462.0 COG4129@1|root,COG4129@2|Bacteria,1TPVH@1239|Firmicutes,4HAEG@91061|Bacilli,1ZCJA@1386|Bacillus 91061|Bacilli S Membrane ygaE - - - - - - - - - - - ArAE_1 k141_23199_2 493475.GARC_2930 4.1e-32 126.0 COG1228@1|root,COG1228@2|Bacteria,1RCA0@1224|Proteobacteria,1S08B@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q COG1228 Imidazolonepropionase and related amidohydrolases - - - - - - - - - - - - Amidohydro_1,CIA30 k141_28999_1 1461580.CCAS010000004_gene643 2.49e-98 298.0 COG0771@1|root,COG0771@2|Bacteria,1TQ3P@1239|Firmicutes,4HA5P@91061|Bacilli,1ZARV@1386|Bacillus 91061|Bacilli M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) murD - 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase_C,Mur_ligase_M k141_29023_1 1294265.JCM21738_570 3e-109 330.0 COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,4HACD@91061|Bacilli,1ZBXI@1386|Bacillus 91061|Bacilli J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) aspS - 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - GAD,tRNA-synt_2,tRNA_anti-codon k141_37291_1 1267211.KI669560_gene2736 6.89e-24 105.0 COG1197@1|root,COG1197@2|Bacteria,4NEPA@976|Bacteroidetes,1IPC5@117747|Sphingobacteriia 976|Bacteroidetes L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd - - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF k141_12599_1 240302.BN982_00937 3.35e-73 220.0 COG3564@1|root,COG3564@2|Bacteria,1V81N@1239|Firmicutes,4HIP2@91061|Bacilli,3NEZ8@45667|Halobacillus 91061|Bacilli S Protein of unknown function (DUF779) - - - ko:K09959 - - - - ko00000 - - - DUF779 k141_14714_1 1347369.CCAD010000048_gene270 2.12e-14 72.4 COG1413@1|root,COG1413@2|Bacteria,1TRJT@1239|Firmicutes,4HBFD@91061|Bacilli,1ZB7F@1386|Bacillus 91061|Bacilli C COG0694 Thioredoxin-like proteins and domains ypgR - - - - - - - - - - - HEAT_2,HEAT_PBS,Nfu_N,Virulence_fact k141_14714_2 345219.Bcoa_3291 1.54e-46 168.0 COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4H9TK@91061|Bacilli,1ZBTF@1386|Bacillus 91061|Bacilli S COG0488 ATPase components of ABC transporters with duplicated ATPase domains yfmR - - ko:K15738 - - - - ko00000,ko02000 3.A.1.120.6 - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn k141_26909_1 240302.BN982_02496 6.71e-123 363.0 COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,4H9VK@91061|Bacilli,3ND3W@45667|Halobacillus 91061|Bacilli G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system rbsA GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0006810,GO:0008144,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015146,GO:0015399,GO:0015405,GO:0015407,GO:0015591,GO:0015608,GO:0015611,GO:0015749,GO:0015750,GO:0015752,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034219,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043211,GO:0043492,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0097159,GO:0097367,GO:1901265,GO:1901363 3.6.3.17 ko:K10441 ko02010,map02010 M00212 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - ABC_tran k141_19576_1 218284.CCDN010000001_gene62 2.2e-242 672.0 COG2233@1|root,COG2233@2|Bacteria,1TQKX@1239|Firmicutes,4HAEU@91061|Bacilli,1ZBWN@1386|Bacillus 91061|Bacilli F Xanthine uracil pyrP - - ko:K02824 - - - - ko00000,ko02000 2.A.40.1.1,2.A.40.1.2 - - Xan_ur_permease k141_21907_1 218284.CCDN010000001_gene44 2.13e-86 262.0 COG0223@1|root,COG0223@2|Bacteria,1TQ32@1239|Firmicutes,4HART@91061|Bacilli,1ZBSP@1386|Bacillus 91061|Bacilli J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus fmt GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 ko:K00604 ko00670,ko00970,map00670,map00970 - R03940 RC00026,RC00165 ko00000,ko00001,ko01000 - - iSB619.SA_RS06010 Formyl_trans_C,Formyl_trans_N k141_8919_1 1453501.JELR01000002_gene50 6.96e-201 577.0 COG1505@1|root,COG1505@2|Bacteria,1NZ7N@1224|Proteobacteria,1T1KJ@1236|Gammaproteobacteria,46621@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG1505 Serine proteases of the peptidase family S9A - - 3.4.21.26 ko:K01322 ko04614,map04614 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S9,Peptidase_S9_N k141_17124_2 1034347.CAHJ01000039_gene4640 2.17e-81 248.0 COG0648@1|root,COG0648@2|Bacteria,1TP1D@1239|Firmicutes,4HB4F@91061|Bacilli,1ZBYQ@1386|Bacillus 91061|Bacilli L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin nfo GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.1.21.2 ko:K01151 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - AP_endonuc_2 k141_26910_1 42565.FP66_12795 3.81e-73 221.0 COG2202@1|root,COG2202@2|Bacteria,1RGZF@1224|Proteobacteria,1S6GG@1236|Gammaproteobacteria,1XPIG@135619|Oceanospirillales 135619|Oceanospirillales T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - - - - - - - - - - PAS_9 k141_26910_2 42565.FP66_12800 0.000125 43.5 COG0477@1|root,COG2814@2|Bacteria,1N2NP@1224|Proteobacteria,1RP1Y@1236|Gammaproteobacteria,1XIMS@135619|Oceanospirillales 135619|Oceanospirillales EGP Major facilitator superfamily - - - - - - - - - - - - MFS_1 k141_33825_1 1116375.VEJY3_12045 4.47e-107 319.0 COG0743@1|root,COG0743@2|Bacteria,1MU4G@1224|Proteobacteria,1RNNW@1236|Gammaproteobacteria,1XT3U@135623|Vibrionales 135623|Vibrionales I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) dxr GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05688 RC01452 ko00000,ko00001,ko00002,ko01000 - - - DXPR_C,DXP_redisom_C,DXP_reductoisom k141_33825_2 674977.VMC_17750 4.52e-178 498.0 COG4589@1|root,COG4589@2|Bacteria,1R34Q@1224|Proteobacteria,1T63B@1236|Gammaproteobacteria,1XSRD@135623|Vibrionales 135623|Vibrionales S Belongs to the CDS family cdsA - 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_1 k141_33825_3 1116375.VEJY3_12055 4.1e-171 478.0 COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,1RMVX@1236|Gammaproteobacteria,1XTBC@135623|Vibrionales 135623|Vibrionales H Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide uppS GO:0000270,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006066,GO:0006629,GO:0006720,GO:0006807,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 ko:K00806 ko00900,ko01110,map00900,map01110 - R06447 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 - - - Prenyltransf k141_33825_4 223926.28807313 7.87e-116 333.0 COG0233@1|root,COG0233@2|Bacteria,1N66T@1224|Proteobacteria,1RN75@1236|Gammaproteobacteria,1XUSS@135623|Vibrionales 135623|Vibrionales J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another frr GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - ko:K02838 - - - - ko00000,ko03012 - - - RRF k141_33825_5 223926.28807314 5.22e-170 475.0 COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,1RMHX@1236|Gammaproteobacteria,1XTPA@135623|Vibrionales 135623|Vibrionales F Catalyzes the reversible phosphorylation of UMP to UDP pyrH - 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 - R00158 RC00002 ko00000,ko00001,ko01000 - - - AA_kinase k141_33825_6 223926.28807315 1.15e-176 495.0 COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,1RPBJ@1236|Gammaproteobacteria,1XSH9@135623|Vibrionales 135623|Vibrionales J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome tsf GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02357 - - - - ko00000,ko03012,ko03029 - - - EF_TS k141_33825_7 945550.VISI1226_08037 1.89e-167 468.0 COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,1RN0Z@1236|Gammaproteobacteria,1XTTD@135623|Vibrionales 135623|Vibrionales J Belongs to the universal ribosomal protein uS2 family rpsB GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02967 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S2 k141_33825_8 1219076.N646_1429 1.36e-210 582.0 COG0024@1|root,COG0024@2|Bacteria,1MU99@1224|Proteobacteria,1RMHN@1236|Gammaproteobacteria,1XU50@135623|Vibrionales 135623|Vibrionales E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed map - 3.4.11.18 ko:K01265 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M24 k141_33825_9 1116375.VEJY3_12085 0.0 1693.0 COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,1RN5T@1236|Gammaproteobacteria,1XU15@135623|Vibrionales 135623|Vibrionales O Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen glnD GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008773,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0070569,GO:0071704,GO:0140096,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.59 ko:K00990 ko02020,map02020 - - - ko00000,ko00001,ko01000 - - - ACT,GlnD_UR_UTase,HD,NTP_transf_2 k141_33825_10 1116375.VEJY3_12090 1.34e-79 237.0 28NXJ@1|root,2ZBV4@2|Bacteria,1RD2V@1224|Proteobacteria,1S3XU@1236|Gammaproteobacteria,1XXER@135623|Vibrionales 135623|Vibrionales S Belongs to the UPF0325 family - - - - - - - - - - - - DUF3461 k141_33825_11 223926.28807320 6.66e-170 475.0 COG0564@1|root,COG0564@2|Bacteria,1N8GW@1224|Proteobacteria,1RMZ7@1236|Gammaproteobacteria,1XSJX@135623|Vibrionales 135623|Vibrionales J COG0564 Pseudouridylate synthases, 23S RNA-specific truC GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.26 ko:K06175 - - - - ko00000,ko01000,ko03016 - - - PseudoU_synth_2 k141_33825_12 674977.VMC_17650 6.54e-58 180.0 COG3098@1|root,COG3098@2|Bacteria,1N7AG@1224|Proteobacteria,1SCXJ@1236|Gammaproteobacteria,1XYYN@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria VV2562 - - - - - - - - - - - DUF446 k141_33825_13 1116375.VEJY3_12105 7.66e-227 627.0 28K8N@1|root,2Z9WC@2|Bacteria,1R5V8@1224|Proteobacteria,1S3I5@1236|Gammaproteobacteria,1XUIP@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF3549) - - - - - - - - - - - - DUF3549 k141_33825_14 223926.28807323 2.53e-64 196.0 2CHAX@1|root,32ZC9@2|Bacteria,1N6X2@1224|Proteobacteria,1SGKD@1236|Gammaproteobacteria,1XY31@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF3301) - - - - - - - - - - - - DUF3301 k141_33825_15 223926.28807324 1.29e-99 291.0 COG1670@1|root,COG1670@2|Bacteria,1RK72@1224|Proteobacteria,1S6IJ@1236|Gammaproteobacteria,1XX66@135623|Vibrionales 135623|Vibrionales J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins - - - - - - - - - - - - Acetyltransf_3 k141_33825_16 223926.28807325 4.32e-48 155.0 2CEIZ@1|root,33JKV@2|Bacteria,1NMVX@1224|Proteobacteria,1SHB5@1236|Gammaproteobacteria,1XYIQ@135623|Vibrionales 135623|Vibrionales - - SO1611 - - - - - - - - - - - - k141_33825_17 223926.28807326 8.9e-99 287.0 COG1671@1|root,COG1671@2|Bacteria,1RCZA@1224|Proteobacteria,1S3QM@1236|Gammaproteobacteria,1XWZB@135623|Vibrionales 135623|Vibrionales S Belongs to the UPF0178 family yaiI - - ko:K09768 - - - - ko00000 - - - DUF188 k141_33825_18 1116375.VEJY3_12135 0.0 976.0 COG2978@1|root,COG2978@2|Bacteria,1MUJ1@1224|Proteobacteria,1RMAI@1236|Gammaproteobacteria,1XSAR@135623|Vibrionales 135623|Vibrionales H p-aminobenzoyl-glutamate transporter - - - ko:K12942 - - - - ko00000 - - - ABG_transport k141_33825_19 1219076.N646_1446 2.16e-54 170.0 COG0254@1|root,COG0254@2|Bacteria,1MZ4D@1224|Proteobacteria,1S8V5@1236|Gammaproteobacteria,1XYB5@135623|Vibrionales 135623|Vibrionales J Ribosomal protein L31 rpmE2 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02909 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L31 k141_33825_20 1116375.VEJY3_12150 7.61e-142 403.0 COG1720@1|root,COG1720@2|Bacteria,1MUF0@1224|Proteobacteria,1RPCX@1236|Gammaproteobacteria,1XU35@135623|Vibrionales 135623|Vibrionales S Uncharacterised protein family UPF0066 yaeB - - - - - - - - - - - UPF0066 k141_33825_21 1051646.VITU9109_11461 0.0 1067.0 COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,1RN5R@1236|Gammaproteobacteria,1XTZ6@135623|Vibrionales 135623|Vibrionales J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS proS GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_2b,tRNA_edit k141_33825_22 1116375.VEJY3_12160 2.07e-40 133.0 2E480@1|root,32Z3X@2|Bacteria,1N70N@1224|Proteobacteria,1SD0N@1236|Gammaproteobacteria,1XYHK@135623|Vibrionales 135623|Vibrionales S Uncharacterised protein family (UPF0253) yaeP - - - - - - - - - - - UPF0253 k141_33825_23 1280001.BAOA01000081_gene2962 7.61e-34 116.0 2EG1V@1|root,339TV@2|Bacteria,1NI0B@1224|Proteobacteria,1SGIA@1236|Gammaproteobacteria,1XZ4Y@135623|Vibrionales 135623|Vibrionales S Domain of unknown function (DUF4250) BT4646 - - - - - - - - - - - DUF4250 k141_33825_24 1116375.VEJY3_12170 0.0 865.0 COG0733@1|root,COG0733@2|Bacteria,1MUZJ@1224|Proteobacteria,1RPCT@1236|Gammaproteobacteria,1XT5X@135623|Vibrionales 135623|Vibrionales S COG0733 Na -dependent transporters of the SNF family - - - ko:K03308 - - - - ko00000 2.A.22.4,2.A.22.5 - - SNF k141_33825_25 223926.28807336 0.0 1448.0 COG3469@1|root,COG3979@1|root,COG3469@2|Bacteria,COG3979@2|Bacteria,1MUUS@1224|Proteobacteria,1RYTJ@1236|Gammaproteobacteria,1XUGW@135623|Vibrionales 135623|Vibrionales G Glycosyl hydrolases family 18 chiA - 3.2.1.14 ko:K01183 ko00520,ko01100,map00520,map01100 - R01206,R02334 RC00467 ko00000,ko00001,ko01000 - GH18 - Glyco_hydro_18 k141_33825_26 1116375.VEJY3_12175 2.34e-143 408.0 28HMH@1|root,2Z7W2@2|Bacteria,1R7XG@1224|Proteobacteria,1S0FH@1236|Gammaproteobacteria,1XTTQ@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF2884) VP2339 - - - - - - - - - - - DUF2884 k141_33825_28 674977.VMC_17440 3.01e-60 202.0 COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,1RS89@1236|Gammaproteobacteria,1XT65@135623|Vibrionales 135623|Vibrionales L COG0514 Superfamily II DNA helicase - - 3.6.4.12 ko:K03654 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecQ_Zn_bind k141_665_1 223926.28807391 8.07e-61 196.0 COG1609@1|root,COG1609@2|Bacteria,1MU1G@1224|Proteobacteria,1RMSP@1236|Gammaproteobacteria,1XTZQ@135623|Vibrionales 135623|Vibrionales K transcriptional regulators galR - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 k141_665_2 675812.VHA_002558 1.23e-219 610.0 COG2017@1|root,COG2017@2|Bacteria,1MVMN@1224|Proteobacteria,1RNZN@1236|Gammaproteobacteria,1XTI3@135623|Vibrionales 135623|Vibrionales G Converts alpha-aldose to the beta-anomer galM - 5.1.3.3 ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 M00632 R01602,R10619 RC00563 ko00000,ko00001,ko00002,ko01000 - - - Aldose_epim k141_37292_1 1453501.JELR01000001_gene1808 2.98e-135 393.0 COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,1RMV1@1236|Gammaproteobacteria,464Z8@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG4992 Ornithine acetylornithine aminotransferase argD - 2.6.1.11,2.6.1.17 ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R02283,R04475 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 k141_12601_1 218284.CCDN010000005_gene3220 4.68e-78 251.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1TR2N@1239|Firmicutes,4H9RR@91061|Bacilli,1ZB2Q@1386|Bacillus 91061|Bacilli EU peptidase yuxL - 3.4.19.1 ko:K01303 - - - - ko00000,ko01000,ko01002 - - - PD40,Peptidase_S9 k141_13764_4 391625.PPSIR1_31978 7.08e-30 117.0 COG2813@1|root,COG2813@2|Bacteria,1RHAE@1224|Proteobacteria,42ZYJ@68525|delta/epsilon subdivisions,2WRXQ@28221|Deltaproteobacteria 28221|Deltaproteobacteria J Protein of unknown function (DUF938) - - - - - - - - - - - - DUF938 k141_8920_1 42565.FP66_13565 2.18e-138 399.0 COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,1RPKC@1236|Gammaproteobacteria,1XHJ0@135619|Oceanospirillales 135619|Oceanospirillales J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) tyrS - 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - S4,tRNA-synt_1b k141_27718_1 1279017.AQYJ01000021_gene2803 2.07e-113 333.0 COG0589@1|root,COG0589@2|Bacteria,1MVZS@1224|Proteobacteria,1SZCP@1236|Gammaproteobacteria,46CY1@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - - - - - - - - - - Usp k141_18451_2 324057.Pjdr2_0734 1.47e-84 264.0 COG0604@1|root,COG0604@2|Bacteria,1TQ0M@1239|Firmicutes,4HA8M@91061|Bacilli,26QXS@186822|Paenibacillaceae 91061|Bacilli C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - - - - - - - - - - - ADH_N,ADH_zinc_N,ADH_zinc_N_2 k141_10143_1 342451.SSP2340 5.81e-14 70.9 COG3182@1|root,COG3182@2|Bacteria,1TSD4@1239|Firmicutes,4HDAS@91061|Bacilli,4GXQ3@90964|Staphylococcaceae 91061|Bacilli S PepSY-associated TM region - - - - - - - - - - - - PepSY_TM k141_10143_2 1218173.BALCAV_0212105 2.62e-11 63.9 COG0584@1|root,COG0584@2|Bacteria,1UBR3@1239|Firmicutes,4H9Z9@91061|Bacilli,1ZD0X@1386|Bacillus 91061|Bacilli C Glycerophosphoryl diester phosphodiesterase family - - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - GDPD k141_5363_1 34506.g6190 2.06e-29 117.0 COG0314@1|root,COG2896@1|root,KOG2876@2759|Eukaryota,KOG3307@2759|Eukaryota,38F0A@33154|Opisthokonta,3B9J0@33208|Metazoa,3D129@33213|Bilateria,40AIY@6231|Nematoda,1KY5Q@119089|Chromadorea,4108B@6236|Rhabditida 33208|Metazoa H Molybdenum Cofactor Synthesis C - - - - - - - - - - - - Fer4_12,MoaC,Mob_synth_C,Radical_SAM k141_5363_2 349521.HCH_04900 8.49e-77 234.0 COG0521@1|root,COG0521@2|Bacteria,1R9W2@1224|Proteobacteria,1S21E@1236|Gammaproteobacteria,1XJ5T@135619|Oceanospirillales 135619|Oceanospirillales H May be involved in the biosynthesis of molybdopterin - - 2.7.7.75 ko:K03638 ko00790,ko01100,map00790,map01100 - R09726 RC00002 ko00000,ko00001,ko01000 - - - MoCF_biosynth k141_5363_4 948565.AFFP02000001_gene1025 2.47e-48 167.0 COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,1RR68@1236|Gammaproteobacteria,1Y7TN@135625|Pasteurellales 135625|Pasteurellales H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate moaA - 4.1.99.22 ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09394 RC03420 ko00000,ko00001,ko01000 - - - Fer4_12,Mob_synth_C,Radical_SAM k141_37293_2 998674.ATTE01000001_gene968 3.27e-15 78.6 COG5002@1|root,COG5002@2|Bacteria,1QU7C@1224|Proteobacteria,1T1PS@1236|Gammaproteobacteria,45ZP2@72273|Thiotrichales 72273|Thiotrichales T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - 2.7.13.3 ko:K07642 ko02020,map02020 M00450,M00645,M00646,M00648 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA k141_25594_1 42565.FP66_07200 1.18e-58 191.0 COG0722@1|root,COG0722@2|Bacteria,1MU5Q@1224|Proteobacteria,1RMAA@1236|Gammaproteobacteria,1XHV5@135619|Oceanospirillales 135619|Oceanospirillales E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) aroF - 2.5.1.54 ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 - - - DAHP_synth_1 k141_666_1 1042377.AFPJ01000051_gene79 1.93e-99 316.0 COG3188@1|root,COG3188@2|Bacteria,1MWV6@1224|Proteobacteria,1SZYH@1236|Gammaproteobacteria,46AZV@72275|Alteromonadaceae 1236|Gammaproteobacteria NU Outer membrane usher protein - - - - - - - - - - - - Usher k141_11303_2 1280001.BAOA01000061_gene4471 4.31e-233 642.0 COG1087@1|root,COG1087@2|Bacteria,1MUHI@1224|Proteobacteria,1RMTU@1236|Gammaproteobacteria,1XSCZ@135623|Vibrionales 135623|Vibrionales M udp-glucose 4-epimerase galE - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - GDP_Man_Dehyd k141_11303_3 1051646.VITU9109_21964 2.29e-22 93.6 COG1609@1|root,COG1609@2|Bacteria,1N8ZA@1224|Proteobacteria,1RSGV@1236|Gammaproteobacteria,1XSKZ@135623|Vibrionales 135623|Vibrionales K COG1609 Transcriptional regulators ebgR - - ko:K12113 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 k141_23228_1 1453501.JELR01000001_gene2167 5.92e-22 94.4 COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,1RMDA@1236|Gammaproteobacteria,46AV9@72275|Alteromonadaceae 1236|Gammaproteobacteria MU Outer membrane efflux protein - - - - - - - - - - - - OEP k141_23228_2 1453501.JELR01000001_gene2168 1.31e-161 468.0 COG0845@1|root,COG0845@2|Bacteria,1PEVY@1224|Proteobacteria,1RPEQ@1236|Gammaproteobacteria,466EU@72275|Alteromonadaceae 1236|Gammaproteobacteria M Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - - - - - - - - - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 k141_23228_3 1453501.JELR01000001_gene2169 0.0 1578.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,464X3@72275|Alteromonadaceae 1236|Gammaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran k141_23228_4 1042377.AFPJ01000009_gene241 1.02e-224 625.0 COG4651@1|root,COG4651@2|Bacteria,1QUQS@1224|Proteobacteria,1T21E@1236|Gammaproteobacteria,46DC1@72275|Alteromonadaceae 1236|Gammaproteobacteria P Sodium/hydrogen exchanger family kefC_1 - - - - - - - - - - - Na_H_Exchanger k141_23228_5 1453501.JELR01000001_gene2172 7e-288 799.0 COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,1RNIY@1236|Gammaproteobacteria,4659T@72275|Alteromonadaceae 1236|Gammaproteobacteria E Aminotransferase class-V - - - - - - - - - - - - Aminotran_5 k141_23228_6 1279017.AQYJ01000025_gene672 1.43e-98 287.0 COG1522@1|root,COG1522@2|Bacteria,1RDB3@1224|Proteobacteria,1S2E1@1236|Gammaproteobacteria,467JC@72275|Alteromonadaceae 1236|Gammaproteobacteria K helix_turn_helix ASNC type grp - - ko:K05800 - - - - ko00000,ko03000 - - - AsnC_trans_reg,HTH_24,HTH_AsnC-type k141_23228_7 1279017.AQYJ01000025_gene671 3.84e-167 470.0 COG3186@1|root,COG3186@2|Bacteria,1MU29@1224|Proteobacteria,1RQBJ@1236|Gammaproteobacteria,46555@72275|Alteromonadaceae 1236|Gammaproteobacteria E Biopterin-dependent aromatic amino acid hydroxylase phhA GO:0003674,GO:0003824,GO:0004497,GO:0004505,GO:0006082,GO:0006520,GO:0006558,GO:0006559,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009987,GO:0016054,GO:0016491,GO:0016705,GO:0016714,GO:0017144,GO:0019439,GO:0019752,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902221,GO:1902222 1.14.16.1 ko:K00500 ko00360,ko00400,ko00790,ko01100,ko01230,map00360,map00400,map00790,map01100,map01230 - R01795,R07211 RC00490 ko00000,ko00001,ko01000 - - - Biopterin_H k141_23228_8 1042377.AFPJ01000009_gene237 2.44e-104 319.0 COG3283@1|root,COG3283@2|Bacteria,1QTS3@1224|Proteobacteria,1RNAI@1236|Gammaproteobacteria,46678@72275|Alteromonadaceae 1236|Gammaproteobacteria EK Transcriptional regulator of aromatic amino acids metabolism tyrR GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008144,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K03721 - - - - ko00000,ko03000 - - - ACT,PAS,PAS_8,Sigma54_activat k141_18452_1 1128421.JAGA01000001_gene2460 5.42e-36 135.0 COG0526@1|root,COG0526@2|Bacteria 2|Bacteria CO cell redox homeostasis ccmG - - ko:K02199 - - - - ko00000,ko03110 - - - AhpC-TSA,Redoxin k141_13794_1 218284.CCDN010000001_gene1615 2.34e-33 123.0 COG1131@1|root,COG1131@2|Bacteria,1TPMQ@1239|Firmicutes,4HA8K@91061|Bacilli,1ZFFV@1386|Bacillus 91061|Bacilli V ATPases associated with a variety of cellular activities - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 k141_13794_2 218284.CCDN010000001_gene1614 2.86e-92 274.0 COG0842@1|root,COG0842@2|Bacteria,1TRF1@1239|Firmicutes,4HI50@91061|Bacilli,1ZQEK@1386|Bacillus 91061|Bacilli V ABC-2 type transporter - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane,ABC2_membrane_3 k141_32509_1 1042377.AFPJ01000053_gene1508 9.03e-49 167.0 COG0457@1|root,COG0457@2|Bacteria,1R9C8@1224|Proteobacteria,1RY5F@1236|Gammaproteobacteria 1236|Gammaproteobacteria S COG0457 FOG TPR repeat - - - - - - - - - - - - TPR_16,TPR_19,TPR_2,TPR_8,Transglut_core k141_31367_1 218284.CCDN010000002_gene2015 2.41e-115 342.0 COG0154@1|root,COG0154@2|Bacteria,1TP0C@1239|Firmicutes,4HBAZ@91061|Bacilli,1ZAT1@1386|Bacillus 91061|Bacilli J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) gatA - 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Amidase k141_2869_1 218284.CCDN010000005_gene3451 4.7e-79 253.0 COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4HBBB@91061|Bacilli,1ZCKA@1386|Bacillus 91061|Bacilli M Penicillin-binding Protein pbpD - 2.4.1.129,3.4.16.4 ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase k141_14737_1 218284.CCDN010000001_gene624 2.05e-112 325.0 COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,4HB1W@91061|Bacilli,1ZBYH@1386|Bacillus 91061|Bacilli E Belongs to the UPF0758 family radC - - ko:K03630 - - - - ko00000 - - - RadC k141_8940_1 223926.28809558 1.94e-174 517.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1XSPS@135623|Vibrionales 135623|Vibrionales U COG0841 Cation multidrug efflux pump acrF - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran k141_11338_1 218284.CCDN010000001_gene1172 1.85e-106 309.0 COG1755@1|root,COG1755@2|Bacteria,1V6IY@1239|Firmicutes,4HIFN@91061|Bacilli,1ZGT0@1386|Bacillus 91061|Bacilli S protein conserved in bacteria ypbQ - - ko:K16168 - - - - ko00000,ko01008 - - - ICMT k141_11338_2 218284.CCDN010000001_gene1171 1.23e-133 385.0 COG3424@1|root,COG3424@2|Bacteria,1TPUK@1239|Firmicutes,4HBHH@91061|Bacilli,1ZC8W@1386|Bacillus 91061|Bacilli Q Naringenin-chalcone synthase bcsA - - ko:K16167 - - - - ko00000,ko01008 - - - Chal_sti_synt_C,Chal_sti_synt_N k141_37319_1 1279017.AQYJ01000024_gene838 9.63e-151 435.0 COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,1RMR2@1236|Gammaproteobacteria,464J6@72275|Alteromonadaceae 1236|Gammaproteobacteria G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate glmM - 5.4.2.10 ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 - R02060 RC00408 ko00000,ko00001,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV k141_1753_1 1294265.JCM21738_4933 4.58e-138 407.0 COG0296@1|root,COG0296@2|Bacteria,1TP4M@1239|Firmicutes,4HAPM@91061|Bacilli,1ZCHU@1386|Bacillus 91061|Bacilli G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position glgB GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901576 2.4.1.18 ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02110 - ko00000,ko00001,ko00002,ko01000,ko04147 - CBM48,GH13 - Alpha-amylase,Alpha-amylase_C,CBM_48 k141_23395_1 1273538.G159_05360 8.13e-38 135.0 COG1366@1|root,COG1366@2|Bacteria,1VTHD@1239|Firmicutes,4HUWD@91061|Bacilli,26GZ5@186818|Planococcaceae 91061|Bacilli T Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor) - - - - - - - - - - - - - k141_37433_1 796606.BMMGA3_13205 4.55e-45 150.0 COG3874@1|root,COG3874@2|Bacteria,1V6H7@1239|Firmicutes,4HIG7@91061|Bacilli,1ZG9C@1386|Bacillus 91061|Bacilli S Sporulation protein YtfJ ytfJ - - - - - - - - - - - Spore_YtfJ k141_37433_2 1294265.JCM21738_4499 1.19e-48 155.0 2E5MF@1|root,330CC@2|Bacteria,1VEG0@1239|Firmicutes,4HMVE@91061|Bacilli,1ZBQY@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2953) ytfI - - - - - - - - - - - DUF2953 k141_33993_1 1294265.JCM21738_289 1.46e-120 352.0 COG1220@1|root,COG1220@2|Bacteria,1TPKQ@1239|Firmicutes,4HA83@91061|Bacilli,1ZCWK@1386|Bacillus 91061|Bacilli O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis hslU - - ko:K03667 - - - - ko00000,ko03110 - - - AAA_2,ClpB_D2-small k141_12765_1 218284.CCDN010000002_gene2001 3.25e-89 273.0 COG4851@1|root,COG4851@2|Bacteria,1TSYE@1239|Firmicutes,4HBI8@91061|Bacilli,1ZBGV@1386|Bacillus 91061|Bacilli S COG4851 Protein involved in sex pheromone biosynthesis camS - - - - - - - - - - - CamS k141_17273_1 218284.CCDN010000002_gene2118 1.2e-149 435.0 COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,4H9VR@91061|Bacilli,1ZB1D@1386|Bacillus 91061|Bacilli E Acetolactate synthase ilvB - 2.2.1.6 ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 M00019,M00570,M00582 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N k141_27097_1 1120973.AQXL01000090_gene2614 1.1e-55 191.0 COG1674@1|root,COG1674@2|Bacteria,1TWB0@1239|Firmicutes,4HCGJ@91061|Bacilli 91061|Bacilli D cell division protein FtsK ftsK - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_SpoIIIE k141_18650_1 218284.CCDN010000001_gene1893 3.34e-158 481.0 COG2176@1|root,COG2176@2|Bacteria,1TPAG@1239|Firmicutes,4H9RF@91061|Bacilli,1ZCIB@1386|Bacillus 91061|Bacilli L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity polC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.7.7 ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_a_NI,DNA_pol3_a_NII,DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon k141_13956_1 1279017.AQYJ01000029_gene3582 2.12e-237 686.0 COG1014@1|root,COG4231@1|root,COG1014@2|Bacteria,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,1RSEQ@1236|Gammaproteobacteria,465RF@72275|Alteromonadaceae 1236|Gammaproteobacteria C Pyruvate ferredoxin/flavodoxin oxidoreductase - - 1.2.7.8 ko:K04090 - - - - br01601,ko00000,ko01000 - - - POR,TPP_enzyme_C k141_13956_4 1279017.AQYJ01000029_gene3544 8.57e-106 324.0 COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,1RNB7@1236|Gammaproteobacteria,464KP@72275|Alteromonadaceae 1236|Gammaproteobacteria S metal-dependent hydrolase with the TIM-barrel fold - - - - - - - - - - - - Amidohydro_3 k141_35226_1 1042377.AFPJ01000025_gene612 2.77e-24 99.4 COG2755@1|root,COG2755@2|Bacteria,1RCXZ@1224|Proteobacteria,1S3QU@1236|Gammaproteobacteria,466ZZ@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG2755 Lysophospholipase L1 and related esterases tesA GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016289,GO:0016290,GO:0016298,GO:0016787,GO:0016788,GO:0016790,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0047617,GO:0052689,GO:0071704,GO:0140096,GO:1901564 3.1.1.5 ko:K10804 ko01040,map01040 - - - ko00000,ko00001,ko01000,ko01004 - - iECED1_1282.ECED1_0521,iLF82_1304.LF82_2242,iNRG857_1313.NRG857_02365 Lipase_GDSL_2 k141_812_1 171693.BN988_00004 3.57e-103 316.0 COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,4H9RY@91061|Bacilli,23IRI@182709|Oceanobacillus 91061|Bacilli S MviN-like protein ytgP GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03328 - - - - ko00000 2.A.66.2 - - Polysacc_synt,Polysacc_synt_C k141_14858_1 218284.CCDN010000002_gene2923 5.28e-96 284.0 COG0300@1|root,COG0300@2|Bacteria,1U5VD@1239|Firmicutes,4HES8@91061|Bacilli,1ZDY5@1386|Bacillus 91061|Bacilli S Enoyl-(Acyl carrier protein) reductase - - - ko:K07124 - - - - ko00000 - - - adh_short k141_14858_2 218284.CCDN010000002_gene2922 4.07e-60 187.0 29NVC@1|root,309TF@2|Bacteria,1U5NJ@1239|Firmicutes,4IFD5@91061|Bacilli,1ZKA7@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_22065_1 1348908.KI518611_gene3372 2.76e-49 168.0 COG5146@1|root,COG5146@2|Bacteria,1V2R2@1239|Firmicutes,4HG04@91061|Bacilli,1ZEC9@1386|Bacillus 91061|Bacilli H Pantothenate kinase coaW - 2.7.1.33 ko:K09680 ko00770,ko01100,map00770,map01100 M00120 R02971,R03018,R04391 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Fumble k141_827_1 1280001.BAOA01000021_gene787 1.64e-37 137.0 COG2895@1|root,COG2895@2|Bacteria,1MUD9@1224|Proteobacteria,1RME4@1236|Gammaproteobacteria,1XSCY@135623|Vibrionales 135623|Vibrionales H Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily cysN GO:0003674,GO:0003824,GO:0004779,GO:0004781,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0044237,GO:0070566 2.7.7.4 ko:K00956 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176,M00596 R00529,R04929 RC02809,RC02889 ko00000,ko00001,ko00002,ko01000 - - - GTP_EFTU k141_827_2 223926.28805277 0.0 1032.0 COG0471@1|root,COG0569@1|root,COG0471@2|Bacteria,COG0569@2|Bacteria,1MU0K@1224|Proteobacteria,1RMI1@1236|Gammaproteobacteria,1XTKK@135623|Vibrionales 135623|Vibrionales P COG0471 Di- and tricarboxylate transporters VP0295 - - - - - - - - - - - CitMHS,TrkA_C k141_827_3 1116375.VEJY3_01470 5.08e-140 396.0 COG0529@1|root,COG0529@2|Bacteria,1MX0D@1224|Proteobacteria,1RNWT@1236|Gammaproteobacteria,1XUJT@135623|Vibrionales 135623|Vibrionales F Catalyzes the synthesis of activated sulfate cysC GO:0003674,GO:0003824,GO:0004020,GO:0006790,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237 2.7.1.25 ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 M00176 R00509,R04928 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - APS_kinase k141_827_4 1280001.BAOA01000021_gene790 1.88e-139 399.0 2AX1N@1|root,31NZV@2|Bacteria,1RI5Q@1224|Proteobacteria,1S6GI@1236|Gammaproteobacteria,1XTQU@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF2806) VV10722 - - - - - - - - - - - DUF2806 k141_32670_2 287.DR97_3031 1.37e-68 246.0 COG0515@1|root,COG2304@1|root,COG0515@2|Bacteria,COG2304@2|Bacteria,1MXU0@1224|Proteobacteria,1T1GT@1236|Gammaproteobacteria,1YKNP@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria KLT Protein tyrosine kinase ppkA - 2.7.11.1 ko:K11912 ko02025,ko03070,map02025,map03070 - - - ko00000,ko00001,ko01000,ko01001,ko02044 - - - Pkinase k141_13992_1 1279017.AQYJ01000026_gene321 5.86e-131 377.0 COG1651@1|root,COG1651@2|Bacteria,1RD39@1224|Proteobacteria,1S3U8@1236|Gammaproteobacteria,466TU@72275|Alteromonadaceae 1236|Gammaproteobacteria M Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process dsbC - 5.3.4.1 ko:K03981 - - - - ko00000,ko01000,ko02044,ko03110 3.A.7.11.1 - - DsbC_N,Thioredoxin_2 k141_13992_2 1122194.AUHU01000005_gene996 1.53e-127 373.0 COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,1RPI8@1236|Gammaproteobacteria,464UI@72275|Alteromonadaceae 1236|Gammaproteobacteria D COG4974 Site-specific recombinase XerD xerD GO:0000150,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008907,GO:0009009,GO:0009037,GO:0009314,GO:0009628,GO:0009987,GO:0015074,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0071139,GO:0071704,GO:0090304,GO:0140097,GO:1901360 - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase k141_14859_1 1042377.AFPJ01000030_gene435 2.11e-90 292.0 COG0587@1|root,COG0587@2|Bacteria,1MUE4@1224|Proteobacteria,1RQA8@1236|Gammaproteobacteria,464B5@72275|Alteromonadaceae 1236|Gammaproteobacteria L DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase dnaE2 GO:0003674,GO:0003824,GO:0003887,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K14162 - - - - ko00000,ko01000,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon k141_10360_2 1134474.O59_000080 2.15e-38 134.0 COG5001@1|root,COG5001@2|Bacteria,1QWTD@1224|Proteobacteria,1T4Q7@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Sensors of blue-light using FAD - - - - - - - - - - - - BLUF k141_11530_1 999541.bgla_2g16060 5.83e-40 142.0 COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,2VI0K@28216|Betaproteobacteria,1K24U@119060|Burkholderiaceae 28216|Betaproteobacteria KT response regulator - - - ko:K02483 - - - - ko00000,ko02022 - - - Response_reg,Trans_reg_C k141_11530_2 1453501.JELR01000001_gene2367 5.21e-24 101.0 COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,1RMSR@1236|Gammaproteobacteria,4646K@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the peptidase S41A family prc GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016787,GO:0019538,GO:0023052,GO:0030163,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - BAGE,DUF3340,PDZ,Peptidase_S41 k141_29168_2 218284.CCDN010000005_gene3311 5.06e-66 201.0 2ANER@1|root,315MJ@2|Bacteria,1V6SU@1239|Firmicutes,4HIW4@91061|Bacilli,1ZG67@1386|Bacillus 91061|Bacilli S stage V sporulation protein spoVAE - - ko:K06407 - - - - ko00000 - - - SpoVAC_SpoVAEB k141_9094_1 1116375.VEJY3_03535 2.32e-153 436.0 COG0784@1|root,COG0835@1|root,COG0784@2|Bacteria,COG0835@2|Bacteria,1N81M@1224|Proteobacteria,1RPS1@1236|Gammaproteobacteria,1XSWX@135623|Vibrionales 135623|Vibrionales T COG0835 Chemotaxis signal transduction protein cheV - - ko:K03415 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - CheW,Response_reg k141_27137_1 1337093.MBE-LCI_2276 1.23e-37 137.0 COG0438@1|root,COG0438@2|Bacteria,1PF38@1224|Proteobacteria,2V83A@28211|Alphaproteobacteria,2PA1W@245186|Loktanella 28211|Alphaproteobacteria M Glycosyltransferase Family 4 - - - - - - - - - - - - Glycos_transf_1 k141_5597_1 1279017.AQYJ01000025_gene655 0.0 881.0 COG0017@1|root,COG0017@2|Bacteria,1MWFV@1224|Proteobacteria,1RMU4@1236|Gammaproteobacteria,464RC@72275|Alteromonadaceae 1236|Gammaproteobacteria J COG0017 Aspartyl asparaginyl-tRNA synthetases asnS GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.22 ko:K01893 ko00970,map00970 M00359,M00360 R03648 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iSDY_1059.SDY_2327 tRNA-synt_2,tRNA_anti-codon k141_20819_1 1279017.AQYJ01000022_gene2606 1.4e-65 205.0 29B18@1|root,2ZY02@2|Bacteria,1REMG@1224|Proteobacteria,1S4B1@1236|Gammaproteobacteria,46AUF@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_23430_1 1461580.CCAS010000021_gene2320 3.75e-157 446.0 28I0M@1|root,2Z85B@2|Bacteria,1TTBC@1239|Firmicutes,4HENN@91061|Bacilli,1ZCDZ@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3231) - - - - - - - - - - - - DUF3231 k141_1767_1 218284.CCDN010000002_gene2092 1.19e-125 363.0 COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,4HA59@91061|Bacilli,1ZB8X@1386|Bacillus 91061|Bacilli I 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain hbd - 1.1.1.157 ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 - R01976,R05576,R06941 RC00029,RC00117 ko00000,ko00001,ko01000 - - - 3HCDH,3HCDH_N k141_16136_1 218284.CCDN010000006_gene3655 1.63e-149 447.0 COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,4HAW9@91061|Bacilli,1ZARC@1386|Bacillus 91061|Bacilli L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate uvrA - - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran k141_34018_2 1123053.AUDG01000009_gene3747 2.17e-99 298.0 COG4336@1|root,COG4336@2|Bacteria,1MW52@1224|Proteobacteria,1RN4P@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Belongs to the D-glutamate cyclase family - - - - - - - - - - - - DUF1445 k141_7738_1 1453501.JELR01000001_gene3150 4.66e-205 580.0 COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,1RQ8B@1236|Gammaproteobacteria,465GI@72275|Alteromonadaceae 1236|Gammaproteobacteria T His Kinase A (phosphoacceptor) domain styS - - - - - - - - - - - HATPase_c,PAS_8 k141_7738_2 1453501.JELR01000001_gene3149 1.28e-252 701.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,465Q7@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - - - - - - - - - - HTH_8,Response_reg,Sigma54_activat k141_7738_3 1453501.JELR01000001_gene3148 4.28e-142 417.0 COG0577@1|root,COG0577@2|Bacteria,1MXFC@1224|Proteobacteria,1RQX0@1236|Gammaproteobacteria,46698@72275|Alteromonadaceae 1236|Gammaproteobacteria V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD k141_11531_2 1347086.CCBA010000015_gene582 3.57e-33 117.0 2B5J4@1|root,31YE2@2|Bacteria,1UAIN@1239|Firmicutes,4IKX4@91061|Bacilli,1ZI5X@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF1450) - - - - - - - - - - - - DUF1450 k141_17291_1 1078085.HMPREF1210_00664 1.57e-71 247.0 COG1404@1|root,COG1404@2|Bacteria,1TPH1@1239|Firmicutes,4HBQH@91061|Bacilli,26DQR@186818|Planococcaceae 91061|Bacilli M Belongs to the peptidase S8 family - - - - - - - - - - - - Inhibitor_I9,PA,Peptidase_S8,SLH,fn3_5 k141_23431_1 218284.CCDN010000001_gene1189 1.13e-95 285.0 COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,4HBDP@91061|Bacilli,1ZAYG@1386|Bacillus 91061|Bacilli S protein conserved in bacteria - - - - - - - - - - - - DegV k141_19761_1 1116375.VEJY3_01540 2.64e-218 603.0 COG0158@1|root,COG0158@2|Bacteria,1MW0E@1224|Proteobacteria,1RNFF@1236|Gammaproteobacteria,1XT96@135623|Vibrionales 135623|Vibrionales G Belongs to the FBPase class 1 family fbp GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0071704,GO:1901135,GO:1901576 3.1.3.11 ko:K03841 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910 M00003,M00165,M00167,M00344 R00762,R04780 RC00017 ko00000,ko00001,ko00002,ko01000,ko04147 - - - FBPase k141_19761_2 1116375.VEJY3_01535 4.01e-125 356.0 COG0221@1|root,COG0221@2|Bacteria,1RA2F@1224|Proteobacteria,1RPVD@1236|Gammaproteobacteria,1XV2X@135623|Vibrionales 135623|Vibrionales C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions ppa GO:0003674,GO:0003824,GO:0004427,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0044237 3.6.1.1 ko:K01507 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - Pyrophosphatase k141_19761_3 1116375.VEJY3_01530 4.72e-72 217.0 COG2105@1|root,COG2105@2|Bacteria,1N94Q@1224|Proteobacteria,1SEE3@1236|Gammaproteobacteria,1XXWK@135623|Vibrionales 135623|Vibrionales S Gamma-glutamyl cyclotransferase, AIG2-like - - - - - - - - - - - - GGACT k141_19761_4 1116375.VEJY3_01525 5.18e-87 284.0 COG2911@1|root,COG2911@2|Bacteria,1MUVD@1224|Proteobacteria,1RMMF@1236|Gammaproteobacteria,1XV86@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria - - - ko:K09800 - - - - ko00000,ko02000 - - - TamB k141_6698_1 675814.VIC_002569 9.64e-73 225.0 COG0444@1|root,COG0444@2|Bacteria,1NYB6@1224|Proteobacteria,1RQNM@1236|Gammaproteobacteria,1XV07@135623|Vibrionales 135623|Vibrionales EP ATPases associated with a variety of cellular activities - - - ko:K02031 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - ABC_tran k141_6698_2 1280001.BAOA01000027_gene4892 1.11e-260 720.0 COG0534@1|root,COG0534@2|Bacteria,1MV6B@1224|Proteobacteria,1RPGF@1236|Gammaproteobacteria,1XVPD@135623|Vibrionales 135623|Vibrionales V MatE - - - ko:K03327 - - - - ko00000,ko02000 2.A.66.1 - - MatE k141_9096_2 236097.ADG881_3228 7.43e-57 179.0 COG0346@1|root,COG0346@2|Bacteria,1RH4X@1224|Proteobacteria,1SAVS@1236|Gammaproteobacteria,1XPAK@135619|Oceanospirillales 135619|Oceanospirillales E Glyoxalase-like domain - - - - - - - - - - - - Glyoxalase k141_27878_2 218284.CCDN010000001_gene769 2.22e-142 412.0 COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,4HA98@91061|Bacilli,1ZDG5@1386|Bacillus 91061|Bacilli JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures cshB GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0070035,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 3.6.4.13 ko:K05592,ko:K18692 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,Helicase_C k141_12784_1 1042377.AFPJ01000004_gene398 1.1e-26 108.0 COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,1RNRX@1236|Gammaproteobacteria,464V1@72275|Alteromonadaceae 1236|Gammaproteobacteria P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) ppk GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006082,GO:0006091,GO:0006139,GO:0006163,GO:0006165,GO:0006464,GO:0006468,GO:0006725,GO:0006753,GO:0006757,GO:0006793,GO:0006796,GO:0006797,GO:0006799,GO:0006807,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009117,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009179,GO:0009185,GO:0009199,GO:0009205,GO:0009259,GO:0009279,GO:0009358,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016778,GO:0017144,GO:0019538,GO:0019637,GO:0019693,GO:0019867,GO:0030312,GO:0030313,GO:0031241,GO:0031975,GO:0032991,GO:0034641,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0043751,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044425,GO:0044462,GO:0044464,GO:0046031,GO:0046034,GO:0046483,GO:0046777,GO:0046939,GO:0055086,GO:0061695,GO:0071704,GO:0071944,GO:0072521,GO:0098552,GO:1901135,GO:1901360,GO:1901564,GO:1901576,GO:1902494,GO:1990234 2.7.4.1 ko:K00937 ko00190,ko03018,map00190,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - iSbBS512_1146.SbBS512_E2875 PP_kinase,PP_kinase_C,PP_kinase_N k141_11533_1 1502850.FG91_02926 2.38e-27 114.0 COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,2U2R6@28211|Alphaproteobacteria,2K2XC@204457|Sphingomonadales 204457|Sphingomonadales E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides pepA_1 - 3.4.11.1 ko:K01255 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - Peptidase_M17,Peptidase_M17_N k141_35262_1 218284.CCDN010000002_gene2554 7.68e-129 381.0 COG4533@1|root,COG4533@2|Bacteria,1TRY2@1239|Firmicutes,4HBZ3@91061|Bacilli,1ZAUC@1386|Bacillus 91061|Bacilli S Sugar transport-related sRNA regulator N-term - - - - - - - - - - - - SBP_bac_5,SgrR_N k141_4251_1 1279017.AQYJ01000024_gene908 3.95e-250 691.0 COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,1RMVY@1236|Gammaproteobacteria,465WX@72275|Alteromonadaceae 1236|Gammaproteobacteria G Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions pfp - 2.7.1.11,2.7.1.90 ko:K21071 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 - R00756,R00764,R02073,R03236,R04779 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PFK k141_4251_2 1279017.AQYJ01000024_gene909 4.12e-279 769.0 COG0773@1|root,COG0773@2|Bacteria,1MUC5@1224|Proteobacteria,1RMMT@1236|Gammaproteobacteria,465PV@72275|Alteromonadaceae 1236|Gammaproteobacteria M Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate mpl - 6.3.2.45 ko:K02558 - - - - ko00000,ko01000 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M k141_4251_3 1279017.AQYJ01000024_gene910 9.59e-120 346.0 COG0163@1|root,COG0163@2|Bacteria,1RA0P@1224|Proteobacteria,1RPN1@1236|Gammaproteobacteria,4665N@72275|Alteromonadaceae 1236|Gammaproteobacteria H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN ubiX GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008694,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.129 ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 M00117 R01238,R02952,R03367,R04985,R04986,R11225 RC00391,RC00814,RC03392 ko00000,ko00001,ko00002,ko01000 - - - Flavoprotein k141_4251_4 1453501.JELR01000001_gene3094 1.82e-42 140.0 COG3526@1|root,COG3526@2|Bacteria,1MZ5V@1224|Proteobacteria,1S8S8@1236|Gammaproteobacteria,468BE@72275|Alteromonadaceae 1236|Gammaproteobacteria O protein conserved in bacteria - - - ko:K07401 - - - - ko00000 - - - Rdx k141_4251_5 1279017.AQYJ01000024_gene912 0.0 1218.0 COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RNWM@1236|Gammaproteobacteria,465X0@72275|Alteromonadaceae 1236|Gammaproteobacteria S exporters of the RND superfamily - - - ko:K07003 - - - - ko00000 - - - MMPL k141_13996_1 1294265.JCM21738_3799 4.04e-113 329.0 COG0714@1|root,COG0714@2|Bacteria,1TPKR@1239|Firmicutes,4HA0T@91061|Bacilli,1ZDJ1@1386|Bacillus 91061|Bacilli S COG0714 MoxR-like ATPases yeaC GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 k141_7739_1 218284.CCDN010000007_gene3877 3.6e-140 401.0 2C8AD@1|root,32RKP@2|Bacteria,1V1BI@1239|Firmicutes,4HFCW@91061|Bacilli,1ZE3F@1386|Bacillus 91061|Bacilli S Gas vesicle synthesis protein GvpL/GvpF - - - - - - - - - - - - GvpL_GvpF k141_18680_1 1116375.VEJY3_02620 1.37e-134 400.0 COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,1RNRX@1236|Gammaproteobacteria,1XSGM@135623|Vibrionales 135623|Vibrionales F Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) ppk GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008976,GO:0009358,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0032991,GO:0044237,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.4.1 ko:K00937 ko00190,ko03018,map00190,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - PP_kinase,PP_kinase_C,PP_kinase_N k141_18680_2 1116375.VEJY3_02615 0.0 893.0 COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,1RN3V@1236|Gammaproteobacteria,1XTUA@135623|Vibrionales 135623|Vibrionales FP Belongs to the GppA Ppx family ppx GO:0003674,GO:0003824,GO:0004309,GO:0006082,GO:0006793,GO:0006797,GO:0006798,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0071704,GO:1901575 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 - R03409 RC00002 ko00000,ko00001,ko01000 - - - Ppx-GppA k141_18680_3 1116375.VEJY3_02610 9.79e-196 546.0 COG0226@1|root,COG0226@2|Bacteria,1MVXP@1224|Proteobacteria,1RQDH@1236|Gammaproteobacteria,1XTH3@135623|Vibrionales 135623|Vibrionales P Phosphate ABC transporter, periplasmic phosphate-binding protein - - - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - PBP_like_2 k141_18680_4 223926.28805553 2.26e-267 734.0 COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,1RN0F@1236|Gammaproteobacteria,1XSR8@135623|Vibrionales 135623|Vibrionales T Phosphate regulon sensor protein phoR - 2.7.13.3 ko:K07636 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - DUF3329,HATPase_c,HisKA,PAS k141_17292_1 1042377.AFPJ01000008_gene1964 1.28e-61 211.0 COG1472@1|root,COG1472@2|Bacteria,1MVIV@1224|Proteobacteria,1RMA0@1236|Gammaproteobacteria,465BV@72275|Alteromonadaceae 1236|Gammaproteobacteria G Family 3 - - 3.2.1.21 ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 - R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - GH3 - CBM_6,Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C k141_17292_2 1453501.JELR01000005_gene1582 2.54e-14 71.6 COG2273@1|root,COG2273@2|Bacteria,1NFHX@1224|Proteobacteria,1RRPK@1236|Gammaproteobacteria,463ZT@72275|Alteromonadaceae 1236|Gammaproteobacteria G Beta-glucanase Beta-glucan synthetase - - - - - - - - - - - - Glyco_hydro_16 k141_27879_1 1294265.JCM21738_3387 2.64e-31 110.0 COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,4HAFP@91061|Bacilli,1ZBJ3@1386|Bacillus 91061|Bacilli V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran k141_34019_1 218284.CCDN010000002_gene2887 3.61e-45 154.0 COG0385@1|root,COG0385@2|Bacteria,1TP85@1239|Firmicutes,4HBG6@91061|Bacilli,1ZB6V@1386|Bacillus 91061|Bacilli S -transporter yocS - - ko:K03453 - - - - ko00000 2.A.28 - iYO844.BSU19350 SBF k141_34019_2 218284.CCDN010000002_gene2886 4.55e-154 442.0 COG0277@1|root,COG0277@2|Bacteria,1TPBC@1239|Firmicutes,4H9UU@91061|Bacilli,1ZCQN@1386|Bacillus 91061|Bacilli C Glycolate oxidase subunit dld - 1.1.2.4,1.1.3.15 ko:K00102,ko:K00104 ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130 - R00197,R00475 RC00042,RC00044 ko00000,ko00001,ko01000 - - - FAD-oxidase_C,FAD_binding_4 k141_19762_2 218284.CCDN010000005_gene3405 6.14e-171 488.0 COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,4HAAI@91061|Bacilli,1ZBC5@1386|Bacillus 91061|Bacilli S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family - - - ko:K03308 - - - - ko00000 2.A.22.4,2.A.22.5 - - SNF k141_13998_1 218284.CCDN010000005_gene3175 5.89e-61 188.0 2D8K4@1|root,32TRG@2|Bacteria,1VCG9@1239|Firmicutes,4HMCV@91061|Bacilli,1ZJ2C@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF1878) yhaI - - - - - - - - - - - DUF1878 k141_14862_1 218284.CCDN010000001_gene31 1.22e-249 699.0 COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,4HAWN@91061|Bacilli,1ZC17@1386|Bacillus 91061|Bacilli L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) recG GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecG_wedge k141_18682_1 218284.CCDN010000001_gene1074 1.19e-15 78.2 COG0438@1|root,COG0438@2|Bacteria,1TPTA@1239|Firmicutes,4HA41@91061|Bacilli,1ZD6V@1386|Bacillus 91061|Bacilli M Glycosyl Transferase - - 2.4.1.337 ko:K19002 ko00561,ko01100,map00561,map01100 - R10850 RC00005,RC00059 ko00000,ko00001,ko01000,ko01003 - GT4 - Glyco_transf_4,Glycos_transf_1 k141_29220_2 1294265.JCM21738_3480 7.47e-52 171.0 COG3343@1|root,COG3343@2|Bacteria,1V6WX@1239|Firmicutes,4HIUK@91061|Bacilli,1ZH95@1386|Bacillus 91061|Bacilli K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling rpoE GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 - ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 - - - HARE-HTH k141_14029_1 935836.JAEL01000136_gene5421 5.29e-129 411.0 COG1404@1|root,COG1404@2|Bacteria,1TPH1@1239|Firmicutes,4HBQH@91061|Bacilli,1ZBS0@1386|Bacillus 91061|Bacilli O Belongs to the peptidase S8 family prtS - 3.4.21.110,3.4.21.96 ko:K01361,ko:K08652 - - - - ko00000,ko01000,ko01002,ko03110 - - - FIVAR,Gram_pos_anchor,Inhibitor_I9,PA,Peptidase_S8,SLH,YSIRK_signal,fn3_5 k141_30266_2 218284.CCDN010000002_gene2928 1.14e-46 151.0 2CEK7@1|root,330II@2|Bacteria,1VFTN@1239|Firmicutes,4HNJY@91061|Bacilli,1ZI0N@1386|Bacillus 91061|Bacilli S WVELL protein yfhJ - - - - - - - - - - - WVELL k141_30266_3 218284.CCDN010000002_gene2927 5.04e-25 93.6 2ERTV@1|root,33JD2@2|Bacteria,1VG3A@1239|Firmicutes,4HPKX@91061|Bacilli,1ZIVJ@1386|Bacillus 91061|Bacilli S reproduction sspK - - ko:K06428 - - - - ko00000 - - - SspK k141_5622_1 218284.CCDN010000001_gene1342 3.25e-121 359.0 COG0025@1|root,COG0025@2|Bacteria,1TR4G@1239|Firmicutes,4HBJR@91061|Bacilli,1ZQCF@1386|Bacillus 91061|Bacilli P Sodium/hydrogen exchanger family - - - ko:K03316 - - - - ko00000 2.A.36 - - Na_H_Exchanger k141_7786_1 42099.EPrPV00000017513 7.78e-06 46.6 COG0484@1|root,KOG0714@2759|Eukaryota,1MBAG@121069|Pythiales 121069|Pythiales O DnaJ homolog, subfamily B, member 8. Source PGD - - - - - - - - - - - - DnaJ k141_7786_2 1035193.HMPREF9073_02776 1.85e-17 85.9 COG0576@1|root,COG0576@2|Bacteria,4NQ6M@976|Bacteroidetes,1I181@117743|Flavobacteriia,1ERWK@1016|Capnocytophaga 976|Bacteroidetes O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ grpE GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - ko:K03687 - - - - ko00000,ko03029,ko03110 - - - GrpE k141_14030_1 218284.CCDN010000005_gene3464 3.85e-63 205.0 COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,4HAAI@91061|Bacilli,1ZBC5@1386|Bacillus 91061|Bacilli S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family - - - ko:K03308 - - - - ko00000 2.A.22.4,2.A.22.5 - - SNF k141_36231_1 218284.CCDN010000001_gene728 2.67e-107 321.0 COG0860@1|root,COG0860@2|Bacteria,1TSFS@1239|Firmicutes,4HACZ@91061|Bacilli,1ZAV0@1386|Bacillus 91061|Bacilli M stage II sporulation protein P spoIIP - - ko:K06385 - - - - ko00000 - - - SpoIIP k141_14901_1 218284.CCDN010000005_gene3288 1.43e-116 337.0 COG4862@1|root,COG4862@2|Bacteria,1UZ7D@1239|Firmicutes,4HDV3@91061|Bacilli,1ZAV4@1386|Bacillus 91061|Bacilli NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC mecA GO:0007154,GO:0008150,GO:0009292,GO:0009294,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0044764,GO:0050896,GO:0051704,GO:0051716,GO:0071496 - ko:K16511 - - - - ko00000 - - - MecA k141_32693_1 1042377.AFPJ01000014_gene1633 1.87e-38 146.0 COG1651@1|root,COG1651@2|Bacteria 2|Bacteria O Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - Thioredoxin_4,VKOR k141_32693_2 1279017.AQYJ01000028_gene2092 2.67e-77 241.0 28HMH@1|root,2Z7W2@2|Bacteria,1R7XG@1224|Proteobacteria,1S0FH@1236|Gammaproteobacteria,46DP2@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF2884) VP2339 - - - - - - - - - - - DUF2884 k141_32693_3 1279017.AQYJ01000028_gene2093 1.43e-06 49.3 COG1913@1|root,COG1913@2|Bacteria,1MY52@1224|Proteobacteria,1RSIP@1236|Gammaproteobacteria,4646U@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF5117) - - - - - - - - - - - - DUF4953,DUF5117 k141_34033_1 1340434.AXVA01000005_gene4746 1.14e-86 263.0 COG1385@1|root,COG1385@2|Bacteria,1V1CT@1239|Firmicutes,4HH8P@91061|Bacilli,1ZAV7@1386|Bacillus 91061|Bacilli J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit rsmE GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.193 ko:K09761 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_RNA k141_1926_6 223926.28807629 3.52e-58 180.0 COG1872@1|root,COG1872@2|Bacteria,1MZ4E@1224|Proteobacteria,1S9AB@1236|Gammaproteobacteria,1XXVE@135623|Vibrionales 135623|Vibrionales S Belongs to the UPF0235 family yggU - - ko:K09131 - - - - ko00000 - - - DUF167 k141_1926_7 1116375.VEJY3_13475 1.44e-93 273.0 2DP15@1|root,3303T@2|Bacteria,1N7NN@1224|Proteobacteria,1S90P@1236|Gammaproteobacteria,1XXF1@135623|Vibrionales 135623|Vibrionales S Domain of unknown function (DUF4426) PP5099 - - - - - - - - - - - DUF4426 k141_1926_8 223926.28807631 1.4e-130 372.0 COG0127@1|root,COG0127@2|Bacteria,1MUK5@1224|Proteobacteria,1S27C@1236|Gammaproteobacteria,1XSX5@135623|Vibrionales 135623|Vibrionales F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions rdgB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 ko:K02428 ko00230,map00230 - R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000 - - - Ham1p_like k141_1926_9 223926.28807632 4.94e-30 115.0 COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,1RN6I@1236|Gammaproteobacteria,1XTWK@135623|Vibrionales 135623|Vibrionales H Involved in the biosynthesis of porphyrin-containing compound yggW - - - - - - - - - - - HemN_C,Radical_SAM k141_22404_1 1294265.JCM21738_4100 2.61e-118 348.0 COG0044@1|root,COG0044@2|Bacteria,1TPQM@1239|Firmicutes,4HA90@91061|Bacilli,1ZAS7@1386|Bacillus 91061|Bacilli F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily pyrC GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 k141_11769_1 1345697.M493_07465 7.75e-56 182.0 COG0614@1|root,COG0614@2|Bacteria,1TR63@1239|Firmicutes,4HB8N@91061|Bacilli,1WFCT@129337|Geobacillus 91061|Bacilli P Periplasmic binding protein - - - ko:K02016 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - Peripla_BP_2 k141_24717_1 1078085.HMPREF1210_00665 1.1e-134 419.0 COG1409@1|root,COG4632@1|root,COG1409@2|Bacteria,COG4632@2|Bacteria,1UWQ2@1239|Firmicutes,4I2G2@91061|Bacilli,26G7J@186818|Planococcaceae 91061|Bacilli G Purple acid Phosphatase, N-terminal domain - - - - - - - - - - - - Metallophos,Pur_ac_phosph_N k141_31531_1 1279017.AQYJ01000022_gene2750 1.36e-64 204.0 COG0584@1|root,COG0584@2|Bacteria 2|Bacteria C glycerophosphodiester phosphodiesterase activity - - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - GDPD k141_31531_3 1042377.AFPJ01000052_gene1556 3.77e-91 275.0 COG3121@1|root,COG3121@2|Bacteria,1NAG3@1224|Proteobacteria,1SCT1@1236|Gammaproteobacteria 1236|Gammaproteobacteria NU Pili and flagellar-assembly chaperone, PapD N-terminal domain - - - - - - - - - - - - PapD_N k141_36384_2 1122194.AUHU01000011_gene1666 6.48e-07 54.3 COG0457@1|root,COG0457@2|Bacteria,1NB8N@1224|Proteobacteria,1SEZN@1236|Gammaproteobacteria,4683W@72275|Alteromonadaceae 1236|Gammaproteobacteria S TPR repeat - - - - - - - - - - - - TPR_1,TPR_10,TPR_12,TPR_16,TPR_6,TPR_8 k141_1040_1 218284.CCDN010000001_gene781 3.74e-111 330.0 COG0477@1|root,COG2814@2|Bacteria,1TQEW@1239|Firmicutes,4HASU@91061|Bacilli,1ZE6N@1386|Bacillus 91061|Bacilli EGP Sugar (and other) transporter - - - ko:K08221 - - - - ko00000,ko02000 2.A.1.32 - - MFS_1 k141_7004_2 1294265.JCM21738_2775 1.3e-109 317.0 COG0290@1|root,COG0290@2|Bacteria,1V1RC@1239|Firmicutes,4HFUS@91061|Bacilli,1ZCBZ@1386|Bacillus 91061|Bacilli J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins infC GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - ko:K02520 - - - - ko00000,ko03012,ko03029 - - - IF3_C,IF3_N k141_9401_2 218284.CCDN010000010_gene4329 1e-119 350.0 COG0489@1|root,COG0489@2|Bacteria,1TQ34@1239|Firmicutes,4HAW4@91061|Bacilli,1ZC2E@1386|Bacillus 91061|Bacilli D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP mrp GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K03593 - - - - ko00000,ko03029,ko03036 - - - FeS_assembly_P,ParA k141_34210_1 305900.GV64_04315 1.12e-28 119.0 COG3188@1|root,COG3188@2|Bacteria,1PTRC@1224|Proteobacteria,1S047@1236|Gammaproteobacteria 1236|Gammaproteobacteria NU E-set like domain cblC - - - - - - - - - - - CooC_C,TcfC,Usher_TcfC k141_12933_1 1042377.AFPJ01000030_gene509 3.78e-22 93.2 2DMIH@1|root,32RT1@2|Bacteria,1RDKU@1224|Proteobacteria,1SFC5@1236|Gammaproteobacteria,46CVG@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_12933_2 1453501.JELR01000002_gene203 1.56e-47 163.0 COG0226@1|root,COG2885@1|root,COG0226@2|Bacteria,COG2885@2|Bacteria,1MVXP@1224|Proteobacteria,1RNK7@1236|Gammaproteobacteria,46D11@72275|Alteromonadaceae 1236|Gammaproteobacteria MP PBP superfamily domain pstS - - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - OmpA,PBP_like_2 k141_3211_3 930169.B5T_01826 3.22e-16 78.2 COG0668@1|root,COG0668@2|Bacteria,1MXD2@1224|Proteobacteria,1RNUB@1236|Gammaproteobacteria,1XH2C@135619|Oceanospirillales 135619|Oceanospirillales M mechanosensitive ion channel - - - ko:K16052 - - - - ko00000,ko02000 1.A.23.4 - - MS_channel k141_19992_2 1191299.AJYX01000096_gene2039 0.0 1226.0 COG0419@1|root,COG0419@2|Bacteria,1MW66@1224|Proteobacteria,1T25Z@1236|Gammaproteobacteria,1Y3AF@135623|Vibrionales 135623|Vibrionales L AAA domain - - - - - - - - - - - - - k141_19992_3 29495.EA26_05595 2.16e-51 169.0 2DMZ2@1|root,32UH6@2|Bacteria,1N4V6@1224|Proteobacteria,1SBYX@1236|Gammaproteobacteria,1XY33@135623|Vibrionales 135623|Vibrionales - - - GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - - - - - - - - - - - k141_19992_4 1116375.VEJY3_22961 1.12e-53 169.0 COG1396@1|root,COG1396@2|Bacteria,1N8ZM@1224|Proteobacteria,1SD5C@1236|Gammaproteobacteria,1XYHC@135623|Vibrionales 135623|Vibrionales K Helix-turn-helix - - - - - - - - - - - - HTH_19,HTH_3 k141_19992_5 675815.VOA_000566 1.4e-234 648.0 COG2842@1|root,COG2842@2|Bacteria,1R9BD@1224|Proteobacteria,1SCZF@1236|Gammaproteobacteria,1XX5T@135623|Vibrionales 135623|Vibrionales S Bacterial TniB protein - - - - - - - - - - - - TniB k141_19992_6 29495.EA26_05580 0.0 1132.0 COG2801@1|root,COG2801@2|Bacteria,1MXCK@1224|Proteobacteria,1RV69@1236|Gammaproteobacteria,1XWAP@135623|Vibrionales 135623|Vibrionales L Integrase core domain - - - ko:K07497 - - - - ko00000 - - - Mu-transpos_C,rve k141_19992_7 29495.EA26_05575 3.53e-132 376.0 2BVEU@1|root,32QUD@2|Bacteria,1RJ4J@1224|Proteobacteria,1S5X1@1236|Gammaproteobacteria,1XYDC@135623|Vibrionales 135623|Vibrionales S TnsA endonuclease N terminal - - - - - - - - - - - - Tn7_Tnp_TnsA_N k141_19992_8 1116375.VEJY3_04355 7.17e-154 434.0 2C985@1|root,2ZJ32@2|Bacteria,1PA8E@1224|Proteobacteria,1STYN@1236|Gammaproteobacteria,1XVKD@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_22406_1 1453501.JELR01000002_gene848 5.48e-92 291.0 COG4225@1|root,COG4225@2|Bacteria,1MU2J@1224|Proteobacteria,1RR65@1236|Gammaproteobacteria,4660R@72275|Alteromonadaceae 1236|Gammaproteobacteria S unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins - - - - - - - - - - - - DUF4861,Glyco_hydro_88 k141_10464_2 218284.CCDN010000007_gene3944 4.63e-38 133.0 COG1994@1|root,COG1994@2|Bacteria,1V6D4@1239|Firmicutes,4H9SF@91061|Bacilli,1ZCSE@1386|Bacillus 91061|Bacilli S Peptidase M50 ywhC - - - - - - - - - - - Peptidase_M50 k141_26034_2 1042377.AFPJ01000024_gene807 0.000925 40.8 COG3487@1|root,COG3487@2|Bacteria,1QTM3@1224|Proteobacteria,1RXQ2@1236|Gammaproteobacteria,468DH@72275|Alteromonadaceae 1236|Gammaproteobacteria P Imelysin - - - ko:K07231 - - - - ko00000 - - - Peptidase_M75 k141_36385_1 218284.CCDN010000005_gene3280 3.62e-46 162.0 COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,4HAMK@91061|Bacilli,1ZBB4@1386|Bacillus 91061|Bacilli E ABC transporter substrate-binding protein oppA - - ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 k141_29391_1 218284.CCDN010000001_gene202 1.67e-35 122.0 2AQNN@1|root,31FW1@2|Bacteria,1UA6S@1239|Firmicutes,4IKHR@91061|Bacilli,1ZH0V@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_4399_1 1565129.JSFF01000012_gene494 2.32e-38 144.0 COG0845@1|root,COG1592@1|root,COG0845@2|Bacteria,COG1592@2|Bacteria,1MVAS@1224|Proteobacteria,1RPBZ@1236|Gammaproteobacteria,2QAK2@267890|Shewanellaceae 1236|Gammaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family cusB - - ko:K07798 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.6.1.4,8.A.1 - - HlyD_D23,HlyD_D4 k141_1928_1 1121091.AUMP01000002_gene2161 5.26e-74 230.0 COG0510@1|root,COG0510@2|Bacteria,1UMFY@1239|Firmicutes,4HBF9@91061|Bacilli 91061|Bacilli M Phosphotransferase ytmP - - - - - - - - - - - APH k141_37606_1 42565.FP66_13485 4.63e-58 191.0 COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,1RMBG@1236|Gammaproteobacteria,1XHIH@135619|Oceanospirillales 135619|Oceanospirillales J Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control pcnB - 2.7.7.19 ko:K00970 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - PolyA_pol,PolyA_pol_RNAbd,PolyA_pol_arg_C k141_29392_1 1094980.Mpsy_2087 1.54e-12 72.8 COG0535@1|root,arCOG00943@2157|Archaea,2Y2FM@28890|Euryarchaeota,2NAHZ@224756|Methanomicrobia 224756|Methanomicrobia S Elongator protein 3, MiaB family, Radical SAM - - - - - - - - - - - - Radical_SAM,SPASM k141_1929_1 406124.ACPC01000005_gene3523 1.5e-98 300.0 COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,4H9VK@91061|Bacilli,1ZB07@1386|Bacillus 91061|Bacilli G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system - - 3.6.3.17 ko:K10548 ko02010,map02010 M00216 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.2.5 - - ABC_tran k141_22408_1 1267535.KB906767_gene2485 2.37e-40 145.0 COG0506@1|root,COG0506@2|Bacteria,3Y2G8@57723|Acidobacteria,2JHRI@204432|Acidobacteriia 204432|Acidobacteriia E Proline dehydrogenase - - - ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 - R10507 RC00083 ko00000,ko00001,ko01000 - - - Pro_dh k141_19993_1 218284.CCDN010000004_gene3056 3.73e-51 167.0 2DKHE@1|root,309GB@2|Bacteria,1U50R@1239|Firmicutes,4IESM@91061|Bacilli,1ZI04@1386|Bacillus 91061|Bacilli S Intracellular proteinase inhibitor - - - - - - - - - - - - BsuPI k141_23748_1 439375.Oant_1359 2.71e-33 125.0 COG0406@1|root,COG0406@2|Bacteria,1QU3R@1224|Proteobacteria,2UZXG@28211|Alphaproteobacteria,1J3Y5@118882|Brucellaceae 28211|Alphaproteobacteria G alpha-ribazole phosphatase activity - - - - - - - - - - - - - k141_12957_4 1042377.AFPJ01000027_gene2668 3.85e-37 125.0 COG3530@1|root,COG3530@2|Bacteria,1N7GT@1224|Proteobacteria,1SCBX@1236|Gammaproteobacteria,468GB@72275|Alteromonadaceae 1236|Gammaproteobacteria S Putative quorum-sensing-regulated virulence factor ypeB - - ko:K09954 - - - - ko00000 - - - QSregVF_b k141_12957_5 1453501.JELR01000002_gene105 5.14e-40 133.0 COG4572@1|root,COG4572@2|Bacteria,1N93H@1224|Proteobacteria,1S94E@1236|Gammaproteobacteria,468DM@72275|Alteromonadaceae 1236|Gammaproteobacteria S ChaB chaB - - ko:K06197 - - - - ko00000 - - - ChaB k141_12957_6 1453501.JELR01000002_gene104 0.0 1244.0 COG3325@1|root,COG3979@1|root,COG3325@2|Bacteria,COG3979@2|Bacteria,1MWAR@1224|Proteobacteria,1RPNS@1236|Gammaproteobacteria,4672D@72275|Alteromonadaceae 1236|Gammaproteobacteria G Glyco_18 chiA - 3.2.1.14 ko:K01183 ko00520,ko01100,map00520,map01100 - R01206,R02334 RC00467 ko00000,ko00001,ko01000 - GH18 - CBM_5_12,ChitinaseA_N,Glyco_hydro_18,REJ k141_20007_3 1042377.AFPJ01000028_gene2185 5.17e-28 107.0 2DQKY@1|root,337IG@2|Bacteria,1NCYH@1224|Proteobacteria,1SCMR@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF4124) - - - - - - - - - - - - DUF4124 k141_20007_4 1279017.AQYJ01000028_gene2047 2.45e-299 823.0 COG0265@1|root,COG0265@2|Bacteria,1PI1V@1224|Proteobacteria,1S3H8@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Trypsin-like peptidase domain - - - - - - - - - - - - PDZ_2,SidE,Trypsin_2 k141_20007_6 1279017.AQYJ01000028_gene2049 5.76e-110 322.0 COG1011@1|root,COG1011@2|Bacteria,1NH15@1224|Proteobacteria,1RP27@1236|Gammaproteobacteria,466G1@72275|Alteromonadaceae 1236|Gammaproteobacteria S Haloacid dehalogenase-like hydrolase yrfG GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008477,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016798,GO:0016799,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050483,GO:0050484 3.1.3.5 ko:K20881 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - HAD_2,Hydrolase k141_20007_7 1089547.KB913013_gene4357 9.07e-13 72.8 COG3714@1|root,COG3714@2|Bacteria,4NMZ9@976|Bacteroidetes,47RZ2@768503|Cytophagia 976|Bacteroidetes S PFAM YhhN-like protein - - - - - - - - - - - - YhhN k141_20007_8 1042377.AFPJ01000028_gene2180 2.31e-188 526.0 COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,1RN6J@1236|Gammaproteobacteria,4641I@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the cysteine synthase cystathionine beta- synthase family cysK - 2.5.1.47 ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03601,R04859 RC00020,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 - - - PALP k141_10478_2 1042377.AFPJ01000037_gene2998 1.26e-270 743.0 COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,1RP4D@1236|Gammaproteobacteria,464FS@72275|Alteromonadaceae 1236|Gammaproteobacteria E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine trpB GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - PALP k141_10478_3 1042377.AFPJ01000037_gene2999 2.17e-92 277.0 COG0135@1|root,COG0135@2|Bacteria,1RA87@1224|Proteobacteria,1S41P@1236|Gammaproteobacteria,466TM@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the TrpF family trpF - 5.3.1.24 ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03509 RC00945 ko00000,ko00001,ko00002,ko01000 - - - PRAI k141_10478_4 1279017.AQYJ01000021_gene2892 4.6e-169 477.0 COG0101@1|root,COG0101@2|Bacteria,1MUYI@1224|Proteobacteria,1RMK2@1236|Gammaproteobacteria,464DE@72275|Alteromonadaceae 1236|Gammaproteobacteria J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs truA GO:0000049,GO:0001522,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 5.4.99.12 ko:K06173 - - - - ko00000,ko01000,ko03016 - - - PseudoU_synth_1 k141_10478_5 1453501.JELR01000001_gene1832 5.11e-280 815.0 COG3170@1|root,COG3170@2|Bacteria,1MXV7@1224|Proteobacteria,1RMM5@1236|Gammaproteobacteria,4646P@72275|Alteromonadaceae 1236|Gammaproteobacteria NU COG3170 Tfp pilus assembly protein FimV fimV - - ko:K08086 - - - - ko00000 - - - LysM,TPR_19 k141_10478_6 1279017.AQYJ01000021_gene2890 2.5e-154 442.0 COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,1RNB6@1236|Gammaproteobacteria,464UG@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate usg GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC k141_1960_1 42565.FP66_12375 2.69e-66 209.0 COG0583@1|root,COG0583@2|Bacteria,1QYAP@1224|Proteobacteria,1RYE8@1236|Gammaproteobacteria,1XIPN@135619|Oceanospirillales 135619|Oceanospirillales K transcriptional regulator - - - ko:K21699 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate k141_1960_2 42565.FP66_12380 3.73e-56 186.0 COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,1RP0C@1236|Gammaproteobacteria,1XHQT@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - 2.6.1.18 ko:K00822 ko00280,ko00410,ko00640,ko01100,map00280,map00410,map00640,map01100 - R00907,R04187 RC00008,RC00062,RC00160 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_3 k141_28042_2 218284.CCDN010000005_gene3421 5.37e-46 148.0 COG4844@1|root,COG4844@2|Bacteria,1VFJJ@1239|Firmicutes,4HNQ8@91061|Bacilli,1ZHVJ@1386|Bacillus 91061|Bacilli S Belongs to the UPF0349 family yuzB - - - - - - - - - - - DUF1450 k141_4416_1 1453501.JELR01000001_gene2693 1.26e-166 474.0 COG0845@1|root,COG0845@2|Bacteria,1MW65@1224|Proteobacteria,1RRHG@1236|Gammaproteobacteria,465HC@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - - - - - - - - - - Biotin_lipoyl_2,HlyD_D23 k141_4416_2 1453501.JELR01000001_gene2692 5.24e-305 863.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,4648N@72275|Alteromonadaceae 1236|Gammaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K18138 ko01501,ko01503,map01501,map01503 M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2 - - ACR_tran k141_7040_1 218284.CCDN010000002_gene2490 3.06e-68 214.0 COG1638@1|root,COG1638@2|Bacteria,1TP3I@1239|Firmicutes,4HB6Q@91061|Bacilli,1ZESG@1386|Bacillus 91061|Bacilli G Bacterial extracellular solute-binding protein, family 7 - - - - - - - - - - - - DctP k141_7040_2 218284.CCDN010000002_gene2491 4.5e-82 246.0 COG3090@1|root,COG3090@2|Bacteria,1VN1P@1239|Firmicutes,4IKVF@91061|Bacilli,1ZHU6@1386|Bacillus 91061|Bacilli G Tripartite ATP-independent periplasmic transporters, DctQ component - - - - - - - - - - - - DctQ k141_16349_1 218284.CCDN010000003_gene3009 2.27e-91 280.0 COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,4HB31@91061|Bacilli,1ZARE@1386|Bacillus 91061|Bacilli EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia pabB GO:0000162,GO:0000287,GO:0003674,GO:0003824,GO:0004049,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006575,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009108,GO:0009308,GO:0009309,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042398,GO:0042401,GO:0042430,GO:0042435,GO:0042558,GO:0042559,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 2.6.1.85 ko:K01665 ko00790,map00790 - R01716 RC00010,RC01418 ko00000,ko00001,ko01000 - - - Anth_synt_I_N,Chorismate_bind k141_15114_2 1288826.MSNKSG1_11023 4.38e-64 251.0 COG1800@1|root,COG1800@2|Bacteria,1R2PF@1224|Proteobacteria,1T5UY@1236|Gammaproteobacteria 1236|Gammaproteobacteria U Involved in the tonB-independent uptake of proteins - - - - - - - - - - - - - k141_15114_3 223926.28808200 9.01e-26 104.0 COG0564@1|root,COG0564@2|Bacteria,1MVJ5@1224|Proteobacteria,1RN61@1236|Gammaproteobacteria,1XSMM@135623|Vibrionales 135623|Vibrionales J COG0564 Pseudouridylate synthases, 23S RNA-specific - - 5.4.99.28,5.4.99.29 ko:K06177 - - - - ko00000,ko01000,ko03009,ko03016 - - - PseudoU_synth_2 k141_24741_1 1219076.N646_3607 2.62e-208 577.0 COG0189@1|root,COG0189@2|Bacteria,1MX62@1224|Proteobacteria,1RM8B@1236|Gammaproteobacteria,1XT40@135623|Vibrionales 135623|Vibrionales F Belongs to the RimK family rimK - - ko:K05844 - - - - ko00000,ko01000,ko03009 - - - RimK k141_24741_2 1116375.VEJY3_16346 3.98e-95 277.0 COG4067@1|root,COG4067@2|Bacteria,1RGX8@1224|Proteobacteria,1S5YR@1236|Gammaproteobacteria,1XUM3@135623|Vibrionales 135623|Vibrionales O protein conserved in archaea - - - - - - - - - - - - Zn_protease k141_24741_3 1116375.VEJY3_16341 5.95e-163 458.0 COG0491@1|root,COG0491@2|Bacteria,1Q667@1224|Proteobacteria,1RSGC@1236|Gammaproteobacteria,1XSVA@135623|Vibrionales 135623|Vibrionales S COG0491 Zn-dependent hydrolases, including glyoxylases VVA1313 - - - - - - - - - - - Lactamase_B k141_24741_4 1116375.VEJY3_16336 0.0 1231.0 COG1166@1|root,COG1166@2|Bacteria,1MU80@1224|Proteobacteria,1RP2J@1236|Gammaproteobacteria,1XSBQ@135623|Vibrionales 135623|Vibrionales H Catalyzes the biosynthesis of agmatine from arginine speA GO:0003674,GO:0003824,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008792,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:1901564,GO:1901566,GO:1901576 4.1.1.19 ko:K01585 ko00330,ko01100,map00330,map01100 M00133 R00566 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N k141_24741_5 1116375.VEJY3_16331 2.88e-218 602.0 COG0010@1|root,COG0010@2|Bacteria,1MVFH@1224|Proteobacteria,1RMH5@1236|Gammaproteobacteria,1XTQC@135623|Vibrionales 135623|Vibrionales E Belongs to the arginase family speB - 3.5.3.11 ko:K01480 ko00330,ko01100,map00330,map01100 M00133 R01157 RC00024,RC00329 ko00000,ko00001,ko00002,ko01000 - - - Arginase k141_24741_6 1116375.VEJY3_16321 0.0 1290.0 COG1770@1|root,COG1770@2|Bacteria,1MUED@1224|Proteobacteria,1RMSV@1236|Gammaproteobacteria,1XU6B@135623|Vibrionales 135623|Vibrionales E Prolyl oligopeptidase, N-terminal beta-propeller domain ptrB - 3.4.21.83 ko:K01354 ko05142,ko05143,map05142,map05143 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S9,Peptidase_S9_N k141_24741_7 1116375.VEJY3_16316 4.74e-205 570.0 COG3203@1|root,COG3203@2|Bacteria,1QTIE@1224|Proteobacteria,1SWVJ@1236|Gammaproteobacteria,1XSH5@135623|Vibrionales 135623|Vibrionales M COG3203 Outer membrane protein (porin) - - - - - - - - - - - - Porin_1,Porin_4 k141_24741_8 1116375.VEJY3_16311 4.58e-230 639.0 COG0457@1|root,COG0457@2|Bacteria,1MVH9@1224|Proteobacteria,1S3PV@1236|Gammaproteobacteria,1XTJS@135623|Vibrionales 135623|Vibrionales S COG0457 FOG TPR repeat - - - - - - - - - - - - BTAD,TPR_16,TPR_19,TPR_8 k141_24741_9 1116375.VEJY3_16306 7.06e-127 363.0 COG0810@1|root,COG0810@2|Bacteria,1R4VE@1224|Proteobacteria,1RQPV@1236|Gammaproteobacteria,1XTNF@135623|Vibrionales 135623|Vibrionales U Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins tonB - - ko:K03832 - - - - ko00000,ko02000 2.C.1.1 - - TonB_C k141_24741_10 223926.28808292 5.42e-67 204.0 COG0848@1|root,COG0848@2|Bacteria,1RI4M@1224|Proteobacteria,1S7MF@1236|Gammaproteobacteria,1XWYC@135623|Vibrionales 135623|Vibrionales U COG0848 Biopolymer transport protein exbD2 - - ko:K03559 - - - - ko00000,ko02000 1.A.30.2.1 - - ExbD k141_22435_1 42565.FP66_03215 1.99e-68 212.0 COG2197@1|root,COG2197@2|Bacteria,1P4TD@1224|Proteobacteria,1S68S@1236|Gammaproteobacteria,1XJ3B@135619|Oceanospirillales 135619|Oceanospirillales T helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE,Response_reg k141_22435_2 42565.FP66_03210 1.67e-88 273.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,1XIC9@135619|Oceanospirillales 135619|Oceanospirillales C Catalyzes the oxidation of acetaldehyde, benzaldehyde, propionaldehyde and other aldehydes - - - ko:K00138 ko00010,ko00620,ko01100,ko01110,ko01120,map00010,map00620,map01100,map01110,map01120 - R00711 RC00047 ko00000,ko00001,ko01000 - - - Aldedh k141_32934_1 1121121.KB894312_gene3179 1.78e-64 199.0 2CDFK@1|root,2Z8BH@2|Bacteria,1V43D@1239|Firmicutes 1239|Firmicutes S DNA N-6-adenine-methyltransferase - - - - - - - - - - - - Dam k141_12958_2 1042377.AFPJ01000028_gene2240 2.38e-23 97.8 COG5607@1|root,COG5607@2|Bacteria,1RH6R@1224|Proteobacteria,1S7KA@1236|Gammaproteobacteria 1236|Gammaproteobacteria S CHAD domain - - - - - - - - - - - - CHAD k141_3237_1 1279017.AQYJ01000027_gene1655 9.53e-128 377.0 COG2223@1|root,COG2223@2|Bacteria,1MU27@1224|Proteobacteria,1RMUK@1236|Gammaproteobacteria,4640N@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG2223 Nitrate nitrite transporter narK - - ko:K02575 ko00910,map00910 M00615 - - ko00000,ko00001,ko00002,ko02000 2.A.1.8 - - MFS_1 k141_24742_1 218284.CCDN010000006_gene3726 1.18e-27 112.0 COG0768@1|root,COG0768@2|Bacteria,1TQHY@1239|Firmicutes,4H9MT@91061|Bacilli,1ZAX9@1386|Bacillus 91061|Bacilli M Penicillin-binding Protein pbpC - 3.4.16.4 ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 M00625 - - ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 - - - MecA_N,PBP_dimer,Transpeptidase k141_23769_1 1279017.AQYJ01000028_gene2130 0.0 914.0 COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,1RYP9@1236|Gammaproteobacteria,465IE@72275|Alteromonadaceae 1236|Gammaproteobacteria E ERAP1-like C-terminal domain - - 3.4.11.14 ko:K01263 - - - - ko00000,ko01000 - - - ERAP1_C,Peptidase_M1 k141_20986_1 218284.CCDN010000003_gene3007 1.01e-91 275.0 COG0760@1|root,COG0760@2|Bacteria,1UZZM@1239|Firmicutes,4HE14@91061|Bacilli,1ZBFZ@1386|Bacillus 91061|Bacilli O peptidyl-prolyl isomerase yacD - 5.2.1.8 ko:K07533 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_2,Rotamase_3,SurA_N_3 k141_32935_1 1116375.VEJY3_17201 1.54e-75 229.0 COG3122@1|root,COG3122@2|Bacteria,1N15V@1224|Proteobacteria,1S5V0@1236|Gammaproteobacteria,1XTMW@135623|Vibrionales 135623|Vibrionales S nucleoprotein polynucleotide-associated enzyme yaiL - - ko:K09912 - - - - ko00000 - - - DUF2058 k141_34230_1 42565.FP66_04255 1.14e-163 468.0 COG0719@1|root,COG0719@2|Bacteria,1MVKY@1224|Proteobacteria,1RQ65@1236|Gammaproteobacteria,1XHSV@135619|Oceanospirillales 135619|Oceanospirillales O Cysteine desulfurase activator complex subunit SufB sufB - - ko:K09014 - - - - ko00000 - - - UPF0051 k141_34230_2 42565.FP66_04250 4.55e-17 75.9 COG1959@1|root,COG1959@2|Bacteria,1N0E2@1224|Proteobacteria,1S915@1236|Gammaproteobacteria,1XMA5@135619|Oceanospirillales 135619|Oceanospirillales K transcriptional regulator - - - - - - - - - - - - Rrf2 k141_9430_1 42565.FP66_14270 1.45e-57 181.0 COG2882@1|root,COG2882@2|Bacteria,1RHFM@1224|Proteobacteria,1S76M@1236|Gammaproteobacteria,1XMAE@135619|Oceanospirillales 135619|Oceanospirillales NOU Flagellar FliJ protein fliJ - - ko:K02413 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FliJ k141_1074_1 1294265.JCM21738_3592 4.06e-108 321.0 COG2905@1|root,COG2905@2|Bacteria,1TQFI@1239|Firmicutes,4HCIW@91061|Bacilli,1ZCEI@1386|Bacillus 91061|Bacilli T Putative nucleotidyltransferase substrate binding domain - - - ko:K07182 - - - - ko00000 - - - CBS,DUF294,DUF294_C,cNMP_binding k141_7043_2 573061.Clocel_0451 0.000645 43.9 COG2909@1|root,COG2909@2|Bacteria,1UIMV@1239|Firmicutes,25B73@186801|Clostridia,36FCW@31979|Clostridiaceae 186801|Clostridia K ATP-dependent transcriptional regulator - - - ko:K03556 - - - - ko00000,ko03000 - - - GerE k141_31833_1 1453501.JELR01000001_gene2729 7e-39 137.0 COG3823@1|root,COG3823@2|Bacteria,1R9YU@1224|Proteobacteria,1RZ5N@1236|Gammaproteobacteria,4679T@72275|Alteromonadaceae 1236|Gammaproteobacteria O Glutamine cyclotransferase - - 2.3.2.5 ko:K00683 - - - - ko00000,ko01000 - - - Glu_cyclase_2 k141_28469_1 218284.CCDN010000001_gene720 9.22e-88 265.0 COG0345@1|root,COG0345@2|Bacteria,1UZ3D@1239|Firmicutes,4HCJ6@91061|Bacilli,1ZBFA@1386|Bacillus 91061|Bacilli E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline comER - - ko:K02239 - M00429 - - ko00000,ko00002,ko02044 - - - F420_oxidored,P5CR_dimer k141_28469_2 218284.CCDN010000001_gene721 1.58e-51 168.0 COG1555@1|root,COG1555@2|Bacteria,1VA3W@1239|Firmicutes,4HKJ1@91061|Bacilli,1ZH4N@1386|Bacillus 91061|Bacilli L COG1555 DNA uptake protein and related DNA-binding proteins comEA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02237 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - HHH_3,SLBB k141_31834_1 171693.BN988_02229 3.01e-91 276.0 COG1063@1|root,COG1063@2|Bacteria,1VRPE@1239|Firmicutes,4HU28@91061|Bacilli 91061|Bacilli E alcohol dehydrogenase - - 1.1.1.1 ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N k141_30708_1 316273.XCV4281 7.28e-53 181.0 COG3507@1|root,COG3507@2|Bacteria,1MWY2@1224|Proteobacteria,1RR93@1236|Gammaproteobacteria,1X2XR@135614|Xanthomonadales 135614|Xanthomonadales G Belongs to the glycosyl hydrolase 43 family - - 3.2.1.37 ko:K01198 ko00520,ko01100,map00520,map01100 - R01433 RC00467 ko00000,ko00001,ko01000 - GH43 - Glyco_hydro_43 k141_30708_2 1056820.KB900633_gene2016 9.11e-80 265.0 COG1472@1|root,COG2755@1|root,COG1472@2|Bacteria,COG2755@2|Bacteria,1MVIV@1224|Proteobacteria,1RMA0@1236|Gammaproteobacteria,2PPXV@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria EG Glycosyl hydrolase family 3 C-terminal domain - - 3.2.1.21 ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 - R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - GH3 - CBM_6,Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C,Lipase_GDSL_2 k141_28471_1 1379270.AUXF01000006_gene5 2.01e-61 210.0 COG0317@1|root,COG0317@2|Bacteria,1ZT5M@142182|Gemmatimonadetes 142182|Gemmatimonadetes KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance - - 2.7.6.5 ko:K00951 ko00230,map00230 - R00429 RC00002,RC00078 ko00000,ko00001,ko01000 - - - ACT_4,HD_4,RelA_SpoT,TGS k141_8237_2 1403313.AXBR01000008_gene662 1.56e-24 100.0 COG0457@1|root,COG0457@2|Bacteria,1V1HX@1239|Firmicutes,4HG5V@91061|Bacilli,1ZCPW@1386|Bacillus 91061|Bacilli S COG0457 FOG TPR repeat yrrB - - - - - - - - - - - TPR_1,TPR_16,TPR_2,TPR_6,TPR_8 k141_31837_1 218284.CCDN010000001_gene177 6.09e-141 407.0 COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,4H9SG@91061|Bacilli,1ZC15@1386|Bacillus 91061|Bacilli E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate hipO GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0050118,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.1.47 ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 M00525 R02733 RC00064,RC00300 ko00000,ko00001,ko00002,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 k141_28475_1 1121104.AQXH01000012_gene291 8.28e-31 120.0 COG3509@1|root,COG3509@2|Bacteria,4NFU9@976|Bacteroidetes 976|Bacteroidetes Q Carboxypeptidase - - - - - - - - - - - - - k141_30711_1 1280001.BAOA01000050_gene1374 5.83e-171 487.0 COG1157@1|root,COG1157@2|Bacteria,1MUH6@1224|Proteobacteria,1RM9W@1236|Gammaproteobacteria,1XSRA@135623|Vibrionales 135623|Vibrionales NU ATP synthase alpha/beta family, nucleotide-binding domain - - 3.6.3.14 ko:K02412 ko02040,map02040 - - - ko00000,ko00001,ko01000,ko02035,ko02044 3.A.6.2,3.A.6.3 - - ATP-synt_ab k141_8240_2 1347086.CCBA010000019_gene1100 1.67e-05 47.8 COG1266@1|root,COG1266@2|Bacteria,1TZF2@1239|Firmicutes,4I8PH@91061|Bacilli,1ZFV1@1386|Bacillus 91061|Bacilli S CAAX protease self-immunity - - - ko:K07052 - - - - ko00000 - - - Abi k141_8241_1 1499968.TCA2_1565 8.63e-57 182.0 COG0861@1|root,COG0861@2|Bacteria,1TQ09@1239|Firmicutes,4HB99@91061|Bacilli,26S9X@186822|Paenibacillaceae 91061|Bacilli P membrane - - - - - - - - - - - - TerC k141_28479_2 218284.CCDN010000001_gene1555 4.38e-51 167.0 COG1011@1|root,COG1011@2|Bacteria,1V3WC@1239|Firmicutes,4HQ3B@91061|Bacilli,1ZQ6Y@1386|Bacillus 91061|Bacilli S HAD-hyrolase-like - - - ko:K07025 - - - - ko00000 - - - HAD_2 k141_30714_1 665952.HMPREF1015_01419 2.88e-12 62.0 2ESX5@1|root,33KFH@2|Bacteria,1VMXQ@1239|Firmicutes,4HRVM@91061|Bacilli,1ZIYT@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3906) - - - - - - - - - - - - DUF3906 k141_30714_2 218284.CCDN010000001_gene1475 8.03e-148 430.0 COG0155@1|root,COG0155@2|Bacteria,1TS58@1239|Firmicutes,4HBEX@91061|Bacilli,1ZBHT@1386|Bacillus 91061|Bacilli P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate nirA - 1.7.7.1 ko:K00366 ko00910,ko01120,map00910,map01120 M00531 R00790 RC00176 ko00000,ko00001,ko00002,ko01000 - - - NIR_SIR,NIR_SIR_ferr k141_28480_1 1266998.ATUJ01000002_gene1883 9.84e-86 266.0 COG0665@1|root,COG0665@2|Bacteria,1MVGP@1224|Proteobacteria,2VFAY@28211|Alphaproteobacteria,2PXGD@265|Paracoccus 28211|Alphaproteobacteria E FAD dependent oxidoreductase - - - - - - - - - - - - DAO k141_15363_2 1116375.VEJY3_23641 3.16e-244 674.0 COG1686@1|root,COG1686@2|Bacteria,1MUU7@1224|Proteobacteria,1RMJA@1236|Gammaproteobacteria,1XVYF@135623|Vibrionales 135623|Vibrionales M Belongs to the peptidase S11 family - - 3.4.16.4 ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - PBP5_C,Peptidase_S11 k141_15363_3 1280001.BAOA01000146_gene2557 7.72e-294 804.0 COG0596@1|root,COG0596@2|Bacteria,1MZ13@1224|Proteobacteria,1RVAM@1236|Gammaproteobacteria,1XTGX@135623|Vibrionales 135623|Vibrionales S hydrolases or acyltransferases (alpha beta hydrolase superfamily) pip - - - - - - - - - - - Abhydrolase_1 k141_15363_4 1348635.BBJY01000006_gene362 2.33e-272 750.0 COG3314@1|root,COG3314@2|Bacteria,1NEAN@1224|Proteobacteria,1RPX6@1236|Gammaproteobacteria,1XVHR@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria - - - - - - - - - - - - Gate k141_15363_5 1348635.BBJY01000006_gene363 2.06e-169 476.0 COG3741@1|root,COG3741@2|Bacteria,1MY4D@1224|Proteobacteria,1RUSZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria E N-formylglutamate amidohydrolase hutG - 3.5.1.68,3.5.3.8 ko:K01458,ko:K01479 ko00340,ko00630,ko01100,map00340,map00630,map01100 M00045 R00525,R02285 RC00165,RC00221,RC00323,RC00681 ko00000,ko00001,ko00002,ko01000 - - - FGase k141_15363_6 1348635.BBJY01000006_gene364 1.29e-298 818.0 COG0402@1|root,COG0402@2|Bacteria,1MUFE@1224|Proteobacteria,1RMZR@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Catalyzes the deimination of N-formimino-L-glutamate to ammonia and N-formyl-L-glutamate hutF - 3.5.3.13 ko:K05603 ko00340,map00340 - R02286 RC00682 ko00000,ko00001,ko01000 - - - Amidohydro_1 k141_15363_7 1348635.BBJY01000006_gene365 1.04e-79 243.0 COG3758@1|root,COG3758@2|Bacteria,1RH9G@1224|Proteobacteria,1S5WK@1236|Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria ydjR - - ko:K09975 - - - - ko00000 - - - HutD k141_15363_8 1116375.VEJY3_23656 1.2e-163 462.0 COG1054@1|root,COG1054@2|Bacteria,1MUFV@1224|Proteobacteria,1RNNU@1236|Gammaproteobacteria,1XTAK@135623|Vibrionales 135623|Vibrionales S Belongs to the UPF0176 family - - - ko:K07146 - - - - ko00000 - - - Rhodanese k141_30715_1 42565.FP66_10085 3.37e-125 369.0 COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,1RMUD@1236|Gammaproteobacteria,1XH7K@135619|Oceanospirillales 135619|Oceanospirillales C NADH-quinone oxidoreductase subunit F fdsB - - ko:K00124 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001 - - - Complex1_51K,NADH_4Fe-4S,SLBB k141_28481_1 1279017.AQYJ01000027_gene1684 1.68e-64 215.0 COG3850@1|root,COG3850@2|Bacteria,1MWZT@1224|Proteobacteria,1RNPP@1236|Gammaproteobacteria,465S0@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG3850 Signal transduction histidine kinase, nitrate nitrite-specific narQ GO:0000155,GO:0000160,GO:0001101,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010167,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0035556,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070887,GO:0071229,GO:0071241,GO:0071249,GO:0071250,GO:0071704,GO:0071944,GO:0080033,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170 2.7.13.3 ko:K07673,ko:K07674 ko02020,map02020 M00471,M00472 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA_3,PilJ k141_8244_1 1453501.JELR01000002_gene522 3e-110 328.0 COG2111@1|root,COG2111@2|Bacteria,1N1CK@1224|Proteobacteria,1RR3K@1236|Gammaproteobacteria,469GM@72275|Alteromonadaceae 1236|Gammaproteobacteria P Domain related to MnhB subunit of Na+/H+ antiporter - - - ko:K05566 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - DUF4040,MnhB k141_30716_1 218284.CCDN010000001_gene1705 3.87e-71 216.0 COG1846@1|root,COG1846@2|Bacteria,1VD1F@1239|Firmicutes,4HME2@91061|Bacilli,1ZH6B@1386|Bacillus 91061|Bacilli K Winged helix DNA-binding domain ydgJ - - - - - - - - - - - MarR k141_30717_1 218284.CCDN010000001_gene1812 3.53e-113 336.0 COG0161@1|root,COG0161@2|Bacteria,1TP9N@1239|Firmicutes,4HAA5@91061|Bacilli,1ZAUQ@1386|Bacillus 91061|Bacilli E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - - - - - - - - - - Aminotran_3 k141_15365_1 42565.FP66_12895 1.38e-69 210.0 COG3215@1|root,COG3215@2|Bacteria,1RGWZ@1224|Proteobacteria,1S4YE@1236|Gammaproteobacteria,1XKB7@135619|Oceanospirillales 135619|Oceanospirillales NU Pilus assembly protein PilZ pilZ - - ko:K02676 - - - - ko00000,ko02035,ko02044 - - - PilZ k141_15365_2 1121943.KB899994_gene989 6.43e-09 55.5 COG0470@1|root,COG0470@2|Bacteria,1R9U1@1224|Proteobacteria,1T1C8@1236|Gammaproteobacteria,1XRRK@135619|Oceanospirillales 135619|Oceanospirillales L DNA polymerase III, delta subunit, C terminal - - - - - - - - - - - - DNA_pol3_delta2,DNApol3-delta_C k141_8245_1 326423.RBAM_023870 4.39e-21 93.2 COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,4H9M4@91061|Bacilli,1ZBWR@1386|Bacillus 91061|Bacilli S Competence protein ComEC comEC - - ko:K02238 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - Competence,DUF4131,Lactamase_B k141_37991_2 1453496.AT03_03775 2.59e-137 407.0 COG0582@1|root,COG0582@2|Bacteria,1R43H@1224|Proteobacteria,1RNI0@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Arm-DNA-bind_3,Phage_integrase k141_37991_3 575788.VS_II1357 6.51e-103 303.0 2903N@1|root,2ZMTN@2|Bacteria,1NPWG@1224|Proteobacteria,1STCN@1236|Gammaproteobacteria,1XWKC@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_37991_5 675815.VOA_001490 0.0 1154.0 2EENK@1|root,338GF@2|Bacteria,1NW6Y@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_37991_7 675814.VIC_001664 2.18e-130 388.0 COG5545@1|root,COG5545@2|Bacteria,1MVGK@1224|Proteobacteria,1SAWT@1236|Gammaproteobacteria,1Y23R@135623|Vibrionales 135623|Vibrionales S Virulence-associated protein E - - - - - - - - - - - - VirE k141_36852_1 1279017.AQYJ01000029_gene3795 4.7e-30 118.0 COG3227@1|root,COG3227@2|Bacteria,1P416@1224|Proteobacteria,1RR7I@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Zinc metalloprotease (Elastase) nprV GO:0005575,GO:0005576,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0009405,GO:0019538,GO:0043170,GO:0044238,GO:0044419,GO:0051704,GO:0071704,GO:1901564 3.4.24.25,3.4.24.26 ko:K01399,ko:K08604 ko01503,ko02024,ko05110,ko05111,map01503,map02024,map05110,map05111 - - - ko00000,ko00001,ko01000,ko01002 - - - FTP,PPC,P_proprotein,PepSY,Peptidase_M4,Peptidase_M4_C k141_31973_1 1116375.VEJY3_15215 1.03e-116 339.0 COG0583@1|root,COG0583@2|Bacteria,1N8FH@1224|Proteobacteria,1RRIV@1236|Gammaproteobacteria,1Y31S@135623|Vibrionales 135623|Vibrionales K Bacterial regulatory helix-turn-helix protein, lysR family - - - - - - - - - - - - HTH_1,LysR_substrate k141_36853_1 1294265.JCM21738_4195 3.81e-142 409.0 COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,4HA1P@91061|Bacilli,1ZC8I@1386|Bacillus 91061|Bacilli L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII dinB2 - - ko:K03502 - - - - ko00000,ko03400 - - - IMS,IMS_C,IMS_HHH k141_31974_1 218284.CCDN010000005_gene3460 2.85e-147 419.0 COG2267@1|root,COG2267@2|Bacteria,1TP59@1239|Firmicutes,4HBHV@91061|Bacilli,1ZQW5@1386|Bacillus 91061|Bacilli I hydrolases or acyltransferases (alpha beta hydrolase superfamily) yugF - - - - - - - - - - - Abhydrolase_1 k141_36856_1 218284.CCDN010000002_gene2142 9.23e-175 491.0 COG1737@1|root,COG1737@2|Bacteria,1TR0N@1239|Firmicutes,4HB9E@91061|Bacilli,1ZCCD@1386|Bacillus 91061|Bacilli K RpiR family transcriptional regulator gntR - - - - - - - - - - - HTH_6,SIS k141_31976_2 1279017.AQYJ01000024_gene984 6.54e-90 276.0 2DMIH@1|root,32RT1@2|Bacteria,1RDKU@1224|Proteobacteria,1SFC5@1236|Gammaproteobacteria,46CVG@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_31976_3 1042377.AFPJ01000030_gene508 6.29e-67 216.0 COG0226@1|root,COG2885@1|root,COG0226@2|Bacteria,COG2885@2|Bacteria,1MVXP@1224|Proteobacteria,1RNK7@1236|Gammaproteobacteria,46D11@72275|Alteromonadaceae 1236|Gammaproteobacteria MP PBP superfamily domain pstS - - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - OmpA,PBP_like_2 k141_30833_1 1116375.VEJY3_04255 2.81e-223 619.0 COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RN5B@1236|Gammaproteobacteria,1XSWC@135623|Vibrionales 135623|Vibrionales E COG0436 Aspartate tyrosine aromatic aminotransferase alaA - 2.6.1.2,2.6.1.66 ko:K14260 ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230 - R00258,R01215 RC00006,RC00008,RC00036 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 k141_30833_2 1116375.VEJY3_04250 2.17e-131 373.0 COG1896@1|root,COG1896@2|Bacteria,1MVGJ@1224|Proteobacteria,1RSED@1236|Gammaproteobacteria,1XTZK@135623|Vibrionales 135623|Vibrionales S Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates yfbR - 3.1.3.89 ko:K08722 ko00240,ko01100,map00240,map01100 - R01569,R01664,R01968,R02088,R02102,R10776 RC00017 ko00000,ko00001,ko01000 - - - HD_3 k141_30833_3 1116375.VEJY3_04245 5.93e-298 815.0 COG0232@1|root,COG0232@2|Bacteria,1MVQ2@1224|Proteobacteria,1RPVJ@1236|Gammaproteobacteria,1XTWV@135623|Vibrionales 135623|Vibrionales F Belongs to the dGTPase family. Type 2 subfamily dgt GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0015949,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 ko:K01129 ko00230,map00230 - R01856 RC00017 ko00000,ko00001,ko01000 - - - HD,HD_assoc k141_30833_4 1116375.VEJY3_04240 3.21e-125 358.0 COG3148@1|root,COG3148@2|Bacteria,1MZCN@1224|Proteobacteria,1S977@1236|Gammaproteobacteria,1XUVF@135623|Vibrionales 135623|Vibrionales S DTW - - - - - - - - - - - - DTW k141_30833_5 1116375.VEJY3_04235 3.92e-115 331.0 COG0705@1|root,COG0705@2|Bacteria,1N8NS@1224|Proteobacteria,1SD4M@1236|Gammaproteobacteria,1XXEV@135623|Vibrionales 135623|Vibrionales S membrane protein (homolog of Drosophila rhomboid) - - - - - - - - - - - - Rhomboid k141_30833_6 223926.28805909 3.58e-50 160.0 COG1555@1|root,COG1555@2|Bacteria,1N6Q3@1224|Proteobacteria,1SC7U@1236|Gammaproteobacteria,1XYXQ@135623|Vibrionales 135623|Vibrionales L COG1555 DNA uptake protein and related DNA-binding proteins - - - ko:K02237 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - HHH_3 k141_30833_7 223926.28805908 0.0 986.0 COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,1RMT5@1236|Gammaproteobacteria,1XT2A@135623|Vibrionales 135623|Vibrionales O Peptidylprolyl isomerase ppiD - 5.2.1.8 ko:K03770 - - - - ko00000,ko01000,ko03110 - - - Rotamase_2,Rotamase_3,SurA_N_3 k141_30833_8 672.VV93_v1c10280 7.65e-56 174.0 COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,1S8VH@1236|Gammaproteobacteria,1XXU2@135623|Vibrionales 135623|Vibrionales L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions hupB GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0005829,GO:0006323,GO:0006996,GO:0008150,GO:0009889,GO:0009987,GO:0010556,GO:0016043,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0051276,GO:0060255,GO:0065007,GO:0071103,GO:0071840,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2001141 - ko:K03530 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding k141_30833_9 223926.28805906 0.0 1457.0 COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,1RPCB@1236|Gammaproteobacteria,1XU6N@135623|Vibrionales 135623|Vibrionales O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner lon - 3.4.21.53 ko:K01338 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - AAA,LON_substr_bdg,Lon_C k141_30833_10 1280001.BAOA01000217_gene244 4.37e-302 824.0 COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,1RN9N@1236|Gammaproteobacteria,1XUMV@135623|Vibrionales 135623|Vibrionales O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP clpX GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - ko:K03544 ko04112,map04112 - - - ko00000,ko00001,ko03110 - - - AAA_2,ClpB_D2-small,zf-C4_ClpX k141_30833_11 1280001.BAOA01000216_gene63 4.89e-144 406.0 COG0740@1|root,COG0740@2|Bacteria,1MV46@1224|Proteobacteria,1RNR6@1236|Gammaproteobacteria,1XU75@135623|Vibrionales 135623|Vibrionales O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins clpP - 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 - - - ko00000,ko00001,ko01000,ko01002 - - - CLP_protease k141_30833_12 1219076.N646_3066 2.54e-287 788.0 COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,1RNZE@1236|Gammaproteobacteria,1XUKH@135623|Vibrionales 135623|Vibrionales D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase tig GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006457,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0071704,GO:0140096,GO:1901564 - ko:K03545 - - - - ko00000 - - - FKBP_C,Trigger_C,Trigger_N k141_30833_13 1116375.VEJY3_04190 0.0 1000.0 COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RQIN@1236|Gammaproteobacteria,1XTW1@135623|Vibrionales 135623|Vibrionales T COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system dctB - 2.7.13.3 ko:K10125 ko02020,map02020 M00504 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,dCache_1 k141_30833_14 1116375.VEJY3_04185 8.71e-296 810.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1XSE5@135623|Vibrionales 135623|Vibrionales T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains dctD - - ko:K10126 ko02020,map02020 M00504 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat k141_30833_15 1116375.VEJY3_04175 7.06e-292 801.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,1RNAM@1236|Gammaproteobacteria,1XTT9@135623|Vibrionales 135623|Vibrionales G TRAP-type C4-dicarboxylate transport system, large permease component dctM GO:0003674,GO:0005215,GO:0005310,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015318,GO:0015556,GO:0015711,GO:0015740,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098656,GO:1903825,GO:1905039 - ko:K11690 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.56.1 - - DctM k141_30833_16 1116375.VEJY3_04170 6.98e-145 410.0 COG3090@1|root,COG3090@2|Bacteria,1R3YK@1224|Proteobacteria,1S0A4@1236|Gammaproteobacteria,1XVDM@135623|Vibrionales 135623|Vibrionales G TRAP-type C4-dicarboxylate transport system, small permease component - GO:0003674,GO:0005215,GO:0005310,GO:0005342,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015318,GO:0015556,GO:0015711,GO:0015740,GO:0015849,GO:0022857,GO:0034220,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0098656,GO:1903825,GO:1905039 - ko:K11689 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.56.1 - - DctQ k141_30833_17 1219065.VPR01S_02_02630 1.62e-229 633.0 COG1638@1|root,COG1638@2|Bacteria,1MVHC@1224|Proteobacteria,1RR72@1236|Gammaproteobacteria,1XT5H@135623|Vibrionales 135623|Vibrionales G TRAP-type C4-dicarboxylate transport system, periplasmic component dctP GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0008150,GO:0015711,GO:0015740,GO:0015849,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464,GO:0046942,GO:0051179,GO:0051234,GO:0071702 - ko:K11688 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.56.1 - - DctP k141_30833_18 1116375.VEJY3_04160 1.68e-253 697.0 COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,1RM9E@1236|Gammaproteobacteria,1XSE0@135623|Vibrionales 135623|Vibrionales P Belongs to the ABC transporter superfamily - - - ko:K10112 ko02010,map02010 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1 - - ABC_tran,TOBE_2 k141_31980_1 180332.JTGN01000001_gene5012 2.19e-19 90.9 COG0223@1|root,COG0223@2|Bacteria,1TQ32@1239|Firmicutes,248ED@186801|Clostridia 186801|Clostridia J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus fmt - 2.1.2.9 ko:K00604 ko00670,ko00970,map00670,map00970 - R03940 RC00026,RC00165 ko00000,ko00001,ko01000 - - - Formyl_trans_C,Formyl_trans_N k141_30834_1 218284.CCDN010000001_gene508 6.22e-124 384.0 COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,4H9T3@91061|Bacilli,1ZCIC@1386|Bacillus 91061|Bacilli L DNA polymerase dnaE - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon k141_31985_2 675816.VIA_001110 2.82e-34 124.0 COG1028@1|root,COG1028@2|Bacteria,1N907@1224|Proteobacteria,1S0GV@1236|Gammaproteobacteria,1XTGE@135623|Vibrionales 135623|Vibrionales IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 k141_31993_1 42565.FP66_02880 8.09e-73 224.0 COG0107@1|root,COG0107@2|Bacteria,1MUS0@1224|Proteobacteria,1RPJQ@1236|Gammaproteobacteria,1XIEI@135619|Oceanospirillales 135619|Oceanospirillales E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit hisF - - ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - - His_biosynth k141_31993_2 42565.FP66_02870 4.37e-10 58.2 COG3068@1|root,COG3068@2|Bacteria,1MWSN@1224|Proteobacteria,1RQDG@1236|Gammaproteobacteria,1XJTP@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF416) - - - ko:K09891 - - - - ko00000 - - - DUF416 k141_31996_1 1196031.ALEG01000072_gene904 7.91e-210 592.0 COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,4HAM7@91061|Bacilli,1ZBG8@1386|Bacillus 91061|Bacilli E COG0747 ABC-type dipeptide transport system, periplasmic component - - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 k141_31997_1 218284.CCDN010000002_gene2207 7.79e-96 287.0 COG1077@1|root,COG1077@2|Bacteria,1TP51@1239|Firmicutes,4HC52@91061|Bacilli,1ZCN2@1386|Bacillus 91061|Bacilli D Rod-share determining protein MreBH mreBH - - ko:K03569 - - - - ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 - - MreB_Mbl k141_30835_1 1042377.AFPJ01000042_gene1030 3.46e-46 160.0 COG1653@1|root,COG1653@2|Bacteria,1MUNZ@1224|Proteobacteria,1RP01@1236|Gammaproteobacteria,465XT@72275|Alteromonadaceae 1236|Gammaproteobacteria G ABC-type sugar transport system, periplasmic component mtlE - - ko:K10227 ko02010,map02010 M00200 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.5 - - SBP_bac_1 k141_30835_2 1347368.HG964407_gene6748 1.45e-08 63.2 COG1940@1|root,COG1940@2|Bacteria,1V1YE@1239|Firmicutes,4HG4A@91061|Bacilli,1ZBUD@1386|Bacillus 91061|Bacilli GK ROK family - - 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - ROK k141_30835_3 1042377.AFPJ01000042_gene1028 1.35e-154 438.0 COG1175@1|root,COG1175@2|Bacteria,1MVF1@1224|Proteobacteria,1RRHX@1236|Gammaproteobacteria,465E4@72275|Alteromonadaceae 1236|Gammaproteobacteria P Binding-protein-dependent transport system inner membrane component mtlF - - ko:K02025,ko:K05814,ko:K10228 ko02010,map02010 M00198,M00200,M00207 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.3,3.A.1.1.5 - - BPD_transp_1 k141_30835_4 1196028.ALEF01000015_gene2588 2.2e-124 362.0 COG0395@1|root,COG0395@2|Bacteria,1UXKP@1239|Firmicutes,4I392@91061|Bacilli,4C6QU@84406|Virgibacillus 91061|Bacilli U Binding-protein-dependent transport system inner membrane component - - - ko:K17246 ko02010,map02010 M00601 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.40 - - BPD_transp_1 k141_30835_5 1042377.AFPJ01000042_gene1026 0.0 936.0 COG0383@1|root,COG0383@2|Bacteria,1R3Q8@1224|Proteobacteria,1RSGZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Alpha-Mannosidase ybgG - 3.2.1.170 ko:K15524 - - - - ko00000,ko01000 - GH38 - Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C k141_30835_6 1042377.AFPJ01000042_gene1025 1.52e-203 582.0 2DB83@1|root,2Z7Q0@2|Bacteria,1NWYZ@1224|Proteobacteria,1SPD0@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF4127) - - - - - - - - - - - - DUF4127 k141_30835_7 1042377.AFPJ01000042_gene1024 4.74e-237 669.0 COG1249@1|root,COG1249@2|Bacteria,1PS20@1224|Proteobacteria 1224|Proteobacteria C FAD dependent oxidoreductase - - - - - - - - - - - - FAD_oxidored k141_30835_8 1144312.PMI09_04030 8.44e-112 334.0 COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQQJ@28211|Alphaproteobacteria,4B8J1@82115|Rhizobiaceae 28211|Alphaproteobacteria P Belongs to the ABC transporter superfamily - - - ko:K10111 ko02010,map02010 M00194,M00200,M00204,M00207,M00491 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.1 - - ABC_tran,TOBE_2 k141_31999_2 1453501.JELR01000002_gene1073 3.35e-62 195.0 COG3175@1|root,COG3175@2|Bacteria,1RDTU@1224|Proteobacteria,1S5XA@1236|Gammaproteobacteria,466DV@72275|Alteromonadaceae 1236|Gammaproteobacteria O oxidase assembly ctaG - - ko:K02258 ko00190,ko01100,ko04714,map00190,map01100,map04714 M00154 - - ko00000,ko00001,ko00002,ko03029 3.D.4.8 - - CtaG_Cox11 k141_30836_1 42565.FP66_12635 1.46e-88 264.0 COG4149@1|root,COG4149@2|Bacteria,1MUXR@1224|Proteobacteria,1RRDV@1236|Gammaproteobacteria,1XJ75@135619|Oceanospirillales 135619|Oceanospirillales P (ABC) transporter modB - - ko:K02018 ko02010,map02010 M00189 - - ko00000,ko00001,ko00002,ko02000 3.A.1.8 - - BPD_transp_1 k141_32001_1 375286.mma_3107 1.4e-17 81.3 COG3428@1|root,COG3428@2|Bacteria,1NBZS@1224|Proteobacteria,2VYKU@28216|Betaproteobacteria 28216|Betaproteobacteria S Bacterial PH domain - - - - - - - - - - - - bPH_4 k141_30837_1 1279017.AQYJ01000026_gene57 1.42e-57 204.0 COG1360@1|root,COG2885@1|root,COG1360@2|Bacteria,COG2885@2|Bacteria,1QW22@1224|Proteobacteria,1T4AK@1236|Gammaproteobacteria,46ACU@72275|Alteromonadaceae 1236|Gammaproteobacteria M OmpA family - - - - - - - - - - - - DUF11,OmpA k141_30837_2 1279017.AQYJ01000026_gene58 3.4e-15 74.3 COG1361@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4932@2|Bacteria,1R5G4@1224|Proteobacteria,1SEWA@1236|Gammaproteobacteria,469S7@72275|Alteromonadaceae 1236|Gammaproteobacteria M Domain of unknown function DUF11 - - - - - - - - - - - - DUF11,SdrD_B k141_32002_1 1121938.AUDY01000008_gene1424 6.14e-120 357.0 COG1292@1|root,COG1292@2|Bacteria,1TRS6@1239|Firmicutes,4HA7U@91061|Bacilli,3NECQ@45667|Halobacillus 91061|Bacilli U BCCT, betaine/carnitine/choline family transporter opuD - - ko:K05020 - - - - ko00000,ko02000 2.A.15.1.1,2.A.15.1.11 - - BCCT k141_30838_1 223926.28809221 2.25e-181 514.0 COG0642@1|root,COG0642@2|Bacteria,1R9IX@1224|Proteobacteria,1SMI3@1236|Gammaproteobacteria,1XTIK@135623|Vibrionales 135623|Vibrionales T COG0642 Signal transduction histidine kinase - - - - - - - - - - - - DUF3404,HATPase_c,HisKA k141_30838_2 223926.28809220 2.3e-148 418.0 COG0745@1|root,COG0745@2|Bacteria,1N7TJ@1224|Proteobacteria,1S21N@1236|Gammaproteobacteria,1XSJI@135623|Vibrionales 135623|Vibrionales K COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - - - - - - - - - - Response_reg,Trans_reg_C k141_30838_3 1116375.VEJY3_19796 8.25e-192 534.0 2BTFF@1|root,32NMR@2|Bacteria,1QJBY@1224|Proteobacteria,1THAZ@1236|Gammaproteobacteria,1XSXM@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF2861) - - - - - - - - - - - - DUF2861 k141_30838_4 223926.28809218 3.65e-42 148.0 28IW1@1|root,2Z8UB@2|Bacteria,1N1QM@1224|Proteobacteria,1RR0J@1236|Gammaproteobacteria,1XSR0@135623|Vibrionales 135623|Vibrionales S F plasmid transfer operon, TraF, protein - - - - - - - - - - - - TraF_2 k141_32005_1 218284.CCDN010000004_gene3097 8.49e-172 491.0 COG2211@1|root,COG2211@2|Bacteria,1TR4D@1239|Firmicutes,4HDCY@91061|Bacilli,1ZDU6@1386|Bacillus 91061|Bacilli G Major Facilitator Superfamily - - - - - - - - - - - - MFS_1,MFS_3 k141_32006_1 1121940.AUDZ01000016_gene9 1.87e-67 213.0 COG4067@1|root,COG4067@2|Bacteria,1RFKA@1224|Proteobacteria,1S40X@1236|Gammaproteobacteria,1XP6P@135619|Oceanospirillales 135619|Oceanospirillales O protein conserved in archaea - - - - - - - - - - - - Zn_protease k141_30841_2 218284.CCDN010000007_gene3887 3.76e-183 521.0 COG1502@1|root,COG1502@2|Bacteria,1TQ2Q@1239|Firmicutes,4H9SX@91061|Bacilli,1ZBA2@1386|Bacillus 91061|Bacilli I PLD-like domain cls2 - - - - - - - - - - - PLDc_2 k141_2657_4 1279017.AQYJ01000027_gene1566 6.39e-246 683.0 COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,1RN7V@1236|Gammaproteobacteria,464MZ@72275|Alteromonadaceae 1236|Gammaproteobacteria S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis hflX GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003924,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006417,GO:0006464,GO:0006468,GO:0006518,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006996,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018105,GO:0018193,GO:0018209,GO:0019001,GO:0019222,GO:0019538,GO:0019843,GO:0022411,GO:0030554,GO:0031323,GO:0031326,GO:0032268,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0032790,GO:0032984,GO:0032988,GO:0034248,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0036211,GO:0036289,GO:0043021,GO:0043022,GO:0043023,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0071826,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:2000112 - ko:K03665 - - - - ko00000,ko03009 - - - GTP-bdg_M,GTP-bdg_N,MMR_HSR1 k141_2657_5 1042377.AFPJ01000032_gene2792 1.06e-186 529.0 COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,1RMUG@1236|Gammaproteobacteria,464H8@72275|Alteromonadaceae 1236|Gammaproteobacteria O HflC and HflK could encode or regulate a protease hflK GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009408,GO:0009628,GO:0009897,GO:0009986,GO:0016020,GO:0016021,GO:0016787,GO:0019538,GO:0031224,GO:0031226,GO:0031233,GO:0032991,GO:0043086,GO:0043170,GO:0044092,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0050790,GO:0050896,GO:0065007,GO:0065009,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0098796,GO:0140096,GO:1901564 - ko:K04088 - M00742 - - ko00000,ko00002,ko01000 - - - Band_7,HflK_N k141_2657_7 1042377.AFPJ01000032_gene2789 1.62e-210 590.0 COG3705@1|root,COG3705@2|Bacteria,1MWIG@1224|Proteobacteria,1RPRQ@1236|Gammaproteobacteria,4649K@72275|Alteromonadaceae 1236|Gammaproteobacteria E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine hisZ - - ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002 - - - tRNA-synt_His k141_2657_8 1042377.AFPJ01000032_gene2788 1.94e-303 829.0 COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,1RNEW@1236|Gammaproteobacteria,464CH@72275|Alteromonadaceae 1236|Gammaproteobacteria F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP purA GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046033,GO:0046040,GO:0046085,GO:0046086,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 - - iECNA114_1301.ECNA114_4393,iECSF_1327.ECSF_4063,iJN746.PP_4889 Adenylsucc_synt k141_7397_1 218284.CCDN010000007_gene3959 9.1e-114 329.0 COG1309@1|root,COG1309@2|Bacteria,1UZQU@1239|Firmicutes,4HD4B@91061|Bacilli,1ZBMP@1386|Bacillus 91061|Bacilli K Transcriptional regulator kstR2_2 - - - - - - - - - - - TetR_N k141_7397_2 935836.JAEL01000071_gene4030 1.78e-17 80.9 COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,1TQAD@1239|Firmicutes,4HCMS@91061|Bacilli,1ZBF6@1386|Bacillus 91061|Bacilli EI Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly icmF GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046906,GO:0046983,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 ko:K11942 - - - - ko00000,ko01000 - - - ArgK,B12-binding,MM_CoA_mutase k141_20383_1 1196028.ALEF01000043_gene523 2.96e-66 220.0 COG0556@1|root,COG0556@2|Bacteria,1TPKB@1239|Firmicutes,4HB81@91061|Bacilli,4C4W6@84406|Virgibacillus 91061|Bacilli L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage uvrB - - ko:K03702 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - Helicase_C,ResIII,UVR,UvrB k141_22839_1 218284.CCDN010000002_gene2534 4.49e-56 184.0 COG0604@1|root,COG0604@2|Bacteria,1TT5J@1239|Firmicutes,4HCXG@91061|Bacilli,1ZBNX@1386|Bacillus 91061|Bacilli C alcohol dehydrogenase - - - - - - - - - - - - - k141_34717_1 1042377.AFPJ01000004_gene368 7.95e-27 107.0 2C1UX@1|root,33FGU@2|Bacteria,1NQE8@1224|Proteobacteria,1SJFD@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_34717_2 1042377.AFPJ01000004_gene369 2.38e-44 155.0 COG0497@1|root,COG0497@2|Bacteria,1PAB3@1224|Proteobacteria,1RZB5@1236|Gammaproteobacteria,468PN@72275|Alteromonadaceae 1236|Gammaproteobacteria L DNA recombination - - - - - - - - - - - - - k141_12194_1 1294265.JCM21738_479 6.15e-75 234.0 COG4980@1|root,COG4980@2|Bacteria,1VKVJ@1239|Firmicutes,4HRQ8@91061|Bacilli,1ZHFT@1386|Bacillus 91061|Bacilli S gas vesicle protein - - - - - - - - - - - - - k141_27527_2 298386.PBPRB1578 8.46e-08 55.1 2DRWY@1|root,33DG4@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k141_2658_1 270374.MELB17_18064 1.58e-100 297.0 COG1024@1|root,COG1024@2|Bacteria,1MWF6@1224|Proteobacteria,1RZJJ@1236|Gammaproteobacteria,469VB@72275|Alteromonadaceae 1236|Gammaproteobacteria I enoyl-CoA hydratase - - - - - - - - - - - - ECH_1 k141_15724_1 1042377.AFPJ01000028_gene2247 7.24e-97 285.0 2F3NU@1|root,33WFU@2|Bacteria,1NWJB@1224|Proteobacteria,1SPGJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_24007_1 218284.CCDN010000008_gene4207 4.49e-182 518.0 COG3104@1|root,COG3104@2|Bacteria,1TP81@1239|Firmicutes,4HAF2@91061|Bacilli,1ZAVZ@1386|Bacillus 91061|Bacilli E amino acid peptide transporter dtpT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03305 - - - - ko00000 2.A.17 - - PTR2 k141_8573_3 1444306.JFZC01000038_gene2904 2.96e-26 102.0 COG0563@1|root,COG0563@2|Bacteria,1UVMY@1239|Firmicutes,4I3RF@91061|Bacilli,26Q69@186821|Sporolactobacillaceae 91061|Bacilli F adenylate kinase activity - - - - - - - - - - - - - k141_16898_1 1449126.JQKL01000036_gene1925 2.26e-64 220.0 COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,247XX@186801|Clostridia,267XD@186813|unclassified Clostridiales 186801|Clostridia J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS - 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1,zf-FPG_IleRS k141_25224_1 1347086.CCBA010000023_gene2153 1.74e-125 375.0 COG1251@1|root,COG1251@2|Bacteria,1TQYX@1239|Firmicutes,4HASM@91061|Bacilli,1ZQ9P@1386|Bacillus 91061|Bacilli C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family nirB - 1.7.1.15 ko:K00362 ko00910,ko01120,map00910,map01120 M00530 R00787 RC00176 ko00000,ko00001,ko00002,ko01000 - - - Fer2_BFD,NIR_SIR,NIR_SIR_ferr,Pyr_redox_2 k141_9723_1 1116472.MGMO_92c00200 2.12e-12 68.6 COG0642@1|root,COG5002@1|root,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1XEIX@135618|Methylococcales 135618|Methylococcales T Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor region - - - - - - - - - - - - HATPase_c,HisKA,PAS_3,Response_reg k141_9723_2 1453501.JELR01000002_gene566 7.63e-39 143.0 COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,1RNA5@1236|Gammaproteobacteria,4641A@72275|Alteromonadaceae 1236|Gammaproteobacteria P Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity katG GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.11.1.21 ko:K03782 ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110 - R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906 RC00034,RC00213,RC00767,RC02141 ko00000,ko00001,ko01000 - - - peroxidase k141_34718_1 1453501.JELR01000002_gene144 2.41e-40 135.0 COG0799@1|root,COG0799@2|Bacteria,1MZEF@1224|Proteobacteria,1S8W3@1236|Gammaproteobacteria,467TU@72275|Alteromonadaceae 1236|Gammaproteobacteria J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation rsfS GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113 - ko:K09710 - - - - ko00000,ko03009 - - - RsfS k141_34718_2 1042377.AFPJ01000030_gene456 2.11e-76 229.0 COG1576@1|root,COG1576@2|Bacteria,1R9Z2@1224|Proteobacteria,1S1ZY@1236|Gammaproteobacteria,466GK@72275|Alteromonadaceae 1236|Gammaproteobacteria J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA rlmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042802,GO:0042803,GO:0043021,GO:0043022,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0044877,GO:0046483,GO:0046983,GO:0070037,GO:0070038,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.177 ko:K00783 - - - - ko00000,ko01000,ko03009 - - - SPOUT_MTase k141_22841_1 218284.CCDN010000001_gene524 8.26e-112 338.0 COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HB1B@91061|Bacilli,1ZC0T@1386|Bacillus 91061|Bacilli T Signal transduction histidine kinase phoR - 2.7.13.3 ko:K07636 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_9,sCache_like k141_16899_1 1307436.PBF_18339 2.8e-56 199.0 COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1UEIC@1239|Firmicutes,4HDD8@91061|Bacilli,1ZAQA@1386|Bacillus 91061|Bacilli T Histidine kinase - - 2.7.13.3 ko:K03407 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 - - - 4HB_MCP_1,CHASE3,GAF_2,HAMP,HATPase_c,HisKA,Response_reg k141_18152_1 1294265.JCM21738_940 1.12e-106 316.0 COG0567@1|root,COG0567@2|Bacteria,1TRDW@1239|Firmicutes,4HAUI@91061|Bacilli,1ZN3Y@1386|Bacillus 91061|Bacilli C 2-oxoglutarate dehydrogenase N-terminus odhA GO:0003674,GO:0003824,GO:0004591,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016624,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045333,GO:0055114,GO:0071704,GO:0072350,GO:1902494,GO:1990204,GO:1990234 1.2.4.2 ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R00621,R01933,R01940,R03316,R08549 RC00004,RC00027,RC00627,RC02743,RC02833,RC02883 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr k141_2659_1 1209072.ALBT01000023_gene4135 1.67e-49 168.0 COG1172@1|root,COG1172@2|Bacteria,1MUM6@1224|Proteobacteria,1RRCX@1236|Gammaproteobacteria,1FG1R@10|Cellvibrio 1236|Gammaproteobacteria G Branched-chain amino acid transport system / permease component ytfT GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - ko:K02057,ko:K10440 ko02010,map02010 M00212,M00221 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - iAPECO1_1312.APECO1_2162,iECH74115_1262.ECH74115_5749,iECOK1_1307.ECOK1_4745,iECSF_1327.ECSF_4119,iLF82_1304.LF82_3716,iUTI89_1310.UTI89_C4834,ic_1306.c5327 BPD_transp_2 k141_2659_2 498211.CJA_3022 8.45e-46 157.0 COG1172@1|root,COG1172@2|Bacteria,1MW9Z@1224|Proteobacteria,1RQ77@1236|Gammaproteobacteria,1FH18@10|Cellvibrio 1236|Gammaproteobacteria G Branched-chain amino acid transport system / permease component yjfF GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - ko:K02057,ko:K10440,ko:K17209 ko02010,map02010 M00212,M00221,M00592 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.21 - iECW_1372.ECW_m4592,iEKO11_1354.EKO11_4080,iWFL_1372.ECW_m4592 BPD_transp_2 k141_24008_1 1042377.AFPJ01000014_gene1671 6.05e-35 123.0 COG0319@1|root,COG0319@2|Bacteria,1MZ67@1224|Proteobacteria,1S6BS@1236|Gammaproteobacteria,467I5@72275|Alteromonadaceae 1236|Gammaproteobacteria J Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ybeY GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - ko:K07042 - - - - ko00000,ko03009 - - - UPF0054 k141_9724_1 338966.Ppro_1753 1.38e-83 265.0 COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,42ME5@68525|delta/epsilon subdivisions,2WKA2@28221|Deltaproteobacteria,43TSA@69541|Desulfuromonadales 28221|Deltaproteobacteria J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS proS - 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_2b,tRNA_edit k141_34719_1 1121085.AUCI01000001_gene3548 2.74e-25 102.0 COG5609@1|root,COG5609@2|Bacteria,1V66Q@1239|Firmicutes,4HICY@91061|Bacilli,1ZFWY@1386|Bacillus 91061|Bacilli S Uncharacterized conserved protein (DUF2294) - - - - - - - - - - - - DUF2294 k141_3874_1 945543.VIBR0546_01124 2.07e-131 405.0 COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,1RMYD@1236|Gammaproteobacteria,1XSUY@135623|Vibrionales 135623|Vibrionales E COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain metH GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 ko:K00548 ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230 M00017 R00946,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans k141_3874_2 223926.28807728 2.71e-282 776.0 COG0025@1|root,COG0025@2|Bacteria,1MW5T@1224|Proteobacteria,1RPH6@1236|Gammaproteobacteria,1XTJG@135623|Vibrionales 135623|Vibrionales P COG0025 NhaP-type Na H and K H antiporters - - - ko:K03316 - - - - ko00000 2.A.36 - - Na_H_Exchanger k141_16900_1 218284.CCDN010000001_gene46 8.75e-190 548.0 COG1198@1|root,COG1198@2|Bacteria,1TNYB@1239|Firmicutes,4H9WW@91061|Bacilli,1ZCBY@1386|Bacillus 91061|Bacilli L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA priA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - ko:K04066 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,ResIII k141_26515_1 1279017.AQYJ01000027_gene1580 0.0 884.0 COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,1RMY7@1236|Gammaproteobacteria,464UQ@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases gltD GO:0003674,GO:0003824,GO:0004355,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045181,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14 ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - iEC042_1314.EC042_3503,iYL1228.KPN_03625 Fer4_11,Fer4_20,Pyr_redox_2 k141_25225_1 218284.CCDN010000001_gene1000 4.94e-138 403.0 COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,4HC50@91061|Bacilli,1ZQ98@1386|Bacillus 91061|Bacilli I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) yqjD GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016421,GO:0016874,GO:0016885,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0071704,GO:0072329,GO:1901575 2.1.3.15,6.4.1.3 ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 M00373,M00741 R01859 RC00097,RC00609 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans k141_2660_1 1294265.JCM21738_3480 3.51e-14 69.3 COG3343@1|root,COG3343@2|Bacteria,1V6WX@1239|Firmicutes,4HIUK@91061|Bacilli,1ZH95@1386|Bacillus 91061|Bacilli K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling rpoE GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 - ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 - - - HARE-HTH k141_8576_1 218284.CCDN010000002_gene2093 4.66e-114 336.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,1ZB7V@1386|Bacillus 91061|Bacilli I Belongs to the thiolase family pcaF - 2.3.1.174,2.3.1.223 ko:K02615 ko00360,ko01120,map00360,map01120 - R00829,R09839 RC00004,RC00326,RC03003 ko00000,ko00001,ko01000 - - - Thiolase_C,Thiolase_N k141_1401_2 218284.CCDN010000001_gene123 1.06e-93 275.0 COG2322@1|root,COG2322@2|Bacteria,1V3WX@1239|Firmicutes,4HHCU@91061|Bacilli,1ZQR4@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF420) - - - ko:K08976 - - - - ko00000 - - - DUF420 k141_26516_1 1294265.JCM21738_4010 1.64e-108 318.0 COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,4HBK9@91061|Bacilli,1ZBHM@1386|Bacillus 91061|Bacilli I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) yngE - - - - - - - - - - iYO844.BSU18210 Carboxyl_trans k141_22843_1 1033734.CAET01000028_gene4552 1.23e-212 597.0 COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,4H9ZF@91061|Bacilli,1ZB20@1386|Bacillus 91061|Bacilli C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate glpK GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 - R00847 RC00002,RC00017 ko00000,ko00001,ko01000,ko04147 - - - FGGY_C,FGGY_N k141_29915_1 1042377.AFPJ01000034_gene2422 1.46e-40 137.0 COG1585@1|root,COG1585@2|Bacteria,1N4FG@1224|Proteobacteria,1S4V9@1236|Gammaproteobacteria,46CZM@72275|Alteromonadaceae 1236|Gammaproteobacteria OU NfeD-like C-terminal, partner-binding - - - ko:K07340 - - - - ko00000 - - - NfeD k141_29915_2 1123237.Salmuc_01202 1.27e-11 69.7 COG5607@1|root,COG5607@2|Bacteria,1RH6R@1224|Proteobacteria,2U7IN@28211|Alphaproteobacteria 28211|Alphaproteobacteria S CHAD - - - - - - - - - - - - CHAD k141_4963_2 1042377.AFPJ01000030_gene472 2.18e-287 792.0 COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,1RP7E@1236|Gammaproteobacteria,465AG@72275|Alteromonadaceae 1236|Gammaproteobacteria J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) gatA - 3.5.1.4,6.3.5.6,6.3.5.7 ko:K01426,ko:K02433 ko00330,ko00360,ko00380,ko00627,ko00643,ko00970,ko01100,ko01120,map00330,map00360,map00380,map00627,map00643,map00970,map01100,map01120 - R02540,R03096,R03180,R03905,R03909,R04212,R05551,R05590 RC00010,RC00100,RC00950,RC01025 ko00000,ko00001,ko01000,ko03029 - - - Amidase k141_4963_3 1453501.JELR01000002_gene160 2.04e-298 820.0 COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,1RP7U@1236|Gammaproteobacteria,465ES@72275|Alteromonadaceae 1236|Gammaproteobacteria J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatB GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 ko:K02434 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - GatB_N,GatB_Yqey k141_4963_4 1042377.AFPJ01000030_gene474 1.41e-45 149.0 2D7C6@1|root,32TNS@2|Bacteria,1MZUP@1224|Proteobacteria,1SA42@1236|Gammaproteobacteria,46CTJ@72275|Alteromonadaceae 1236|Gammaproteobacteria S aminopeptidase IV02_13490 - - - - - - - - - - - - k141_4963_6 1279017.AQYJ01000024_gene1022 0.0 899.0 COG1835@1|root,COG1835@2|Bacteria,1MV2W@1224|Proteobacteria,1RQS2@1236|Gammaproteobacteria,465QX@72275|Alteromonadaceae 1236|Gammaproteobacteria I Acyltransferase - - - - - - - - - - - - Acyl_transf_3 k141_4963_7 102125.Xen7305DRAFT_00024850 2.51e-08 63.5 COG1874@1|root,COG1874@2|Bacteria,1GH6K@1117|Cyanobacteria,3VNCP@52604|Pleurocapsales 1117|Cyanobacteria G Beta-galactosidase - - - - - - - - - - - - - k141_4963_8 1279017.AQYJ01000024_gene1021 4.51e-267 743.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,464SM@72275|Alteromonadaceae 1236|Gammaproteobacteria JKL DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA rhlB GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0019904,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0090304,GO:0097718,GO:0140098,GO:1901360,GO:1901361,GO:1901575 3.6.4.13 ko:K03732 ko03018,map03018 M00394 - - ko00000,ko00001,ko00002,ko01000,ko03019 - - - DEAD,Helicase_C,RhlB k141_4963_9 1453501.JELR01000002_gene164 6.97e-110 320.0 COG2259@1|root,COG2259@2|Bacteria,1RBZP@1224|Proteobacteria,1S28E@1236|Gammaproteobacteria,466DA@72275|Alteromonadaceae 1236|Gammaproteobacteria S DoxX - - - ko:K15977 - - - - ko00000 - - - DoxX k141_4963_10 1453501.JELR01000002_gene165 4.13e-256 711.0 COG0534@1|root,COG0534@2|Bacteria,1MUAM@1224|Proteobacteria,1RP5M@1236|Gammaproteobacteria,464IA@72275|Alteromonadaceae 1236|Gammaproteobacteria V COG0534 Na -driven multidrug efflux pump norM GO:0003674,GO:0005215,GO:0006810,GO:0006855,GO:0008150,GO:0015238,GO:0015893,GO:0022857,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0046677,GO:0050896,GO:0051179,GO:0051234,GO:0055085 - ko:K03327 - - - - ko00000,ko02000 2.A.66.1 - - MatE k141_4963_11 1279017.AQYJ01000024_gene1017 2.04e-212 603.0 COG3608@1|root,COG3608@2|Bacteria,1MUAA@1224|Proteobacteria,1RNQQ@1236|Gammaproteobacteria,464NX@72275|Alteromonadaceae 1236|Gammaproteobacteria S Succinylglutamate desuccinylase / Aspartoacylase family - - - ko:K06987 - - - - ko00000 - - - AstE_AspA k141_4963_13 1136138.JH604623_gene2739 9.24e-95 298.0 COG0216@1|root,COG2890@1|root,COG0216@2|Bacteria,COG2890@2|Bacteria,1MV28@1224|Proteobacteria 1224|Proteobacteria J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA prfA GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02835 - - - - ko00000,ko03012 - - - PCRF,RF-1 k141_4963_14 1453501.JELR01000002_gene176 3.21e-230 637.0 COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,1RM7Q@1236|Gammaproteobacteria,464HV@72275|Alteromonadaceae 1236|Gammaproteobacteria J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA prfA GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02835 - - - - ko00000,ko03012 - - - PCRF,RF-1 k141_4963_15 1279017.AQYJ01000024_gene1013 0.00045 42.4 COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,1RNQ8@1236|Gammaproteobacteria,463YI@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) hemA GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006536,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008883,GO:0009058,GO:0009064,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019353,GO:0019438,GO:0019752,GO:0033013,GO:0033014,GO:0033526,GO:0034641,GO:0042168,GO:0042440,GO:0042802,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.2.1.70 ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R04109 RC00055,RC00149 ko00000,ko00001,ko00002,ko01000 - - iECNA114_1301.ECNA114_1375,iECSF_1327.ECSF_1186,iUTI89_1310.UTI89_C1404 GlutR_N,GlutR_dimer,Shikimate_DH k141_2661_1 218284.CCDN010000008_gene4175 1.28e-23 97.1 COG2141@1|root,COG2141@2|Bacteria,1TPRS@1239|Firmicutes,4H9R2@91061|Bacilli,1ZB1E@1386|Bacillus 91061|Bacilli C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases ywcH GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - - - - - - - - - - Bac_luciferase k141_27529_1 1294265.JCM21738_1631 6.88e-18 80.1 COG0363@1|root,COG0363@2|Bacteria,1TP10@1239|Firmicutes,4HAG4@91061|Bacilli,1ZD28@1386|Bacillus 91061|Bacilli G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion nagB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 3.5.99.6 ko:K02564 ko00520,ko01100,map00520,map01100 - R00765 RC00163 ko00000,ko00001,ko01000 - - iYO844.BSU35020 Glucosamine_iso k141_27529_2 1294265.JCM21738_1630 5.21e-71 219.0 COG2188@1|root,COG2188@2|Bacteria,1UYBW@1239|Firmicutes,4HDDG@91061|Bacilli,1ZBS6@1386|Bacillus 91061|Bacilli K transcriptional yvoA - - ko:K03710 - - - - ko00000,ko03000 - - - GntR,UTRA k141_8577_1 1117647.M5M_18365 1.52e-73 225.0 2EKD9@1|root,33E3J@2|Bacteria,1RIMW@1224|Proteobacteria,1S7IQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_6312_2 1042377.AFPJ01000024_gene766 2.58e-84 257.0 COG2995@1|root,COG2995@2|Bacteria,1N2QU@1224|Proteobacteria,1S9RM@1236|Gammaproteobacteria,46CS5@72275|Alteromonadaceae 1236|Gammaproteobacteria S Paraquat-inducible protein A pqiA2 - - ko:K03808 - - - - ko00000 - - - PqiA k141_6312_3 1453501.JELR01000002_gene617 1.31e-228 644.0 COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,1RQQV@1236|Gammaproteobacteria,46448@72275|Alteromonadaceae 1236|Gammaproteobacteria MU COG1538 Outer membrane protein tolC - - ko:K12340 ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133 M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko02044 1.B.17,2.A.6.2 - - OEP k141_6312_4 1279017.AQYJ01000028_gene2205 6.06e-212 597.0 COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,1RNBR@1236|Gammaproteobacteria,464WA@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG1519 3-deoxy-D-manno-octulosonic-acid transferase waaA GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 ko:K02527 ko00540,ko01100,map00540,map01100 M00060,M00080 R04658,R05074,R09763 RC00009,RC00077,RC00247 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT30 iECNA114_1301.ECNA114_3778,iUMNK88_1353.UMNK88_4417 Glycos_transf_1,Glycos_transf_N k141_14518_1 1294265.JCM21738_617 1.19e-108 315.0 COG1530@1|root,COG1530@2|Bacteria,1TQS4@1239|Firmicutes,4HC3Q@91061|Bacilli,1ZCCF@1386|Bacillus 91061|Bacilli J ribonuclease, Rne Rng family rng - - ko:K08301 - - - - ko00000,ko01000,ko03009,ko03019 - - - RNase_E_G,S1 k141_18171_1 265729.GS18_0210430 1.97e-69 217.0 COG2227@1|root,COG2227@2|Bacteria,1VZEI@1239|Firmicutes,4HDZM@91061|Bacilli,1ZE3K@1386|Bacillus 91061|Bacilli H Methyltransferase domain - - - - - - - - - - - - Methyltransf_25 k141_377_1 1453501.JELR01000002_gene1263 2.76e-125 373.0 COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,1RNQM@1236|Gammaproteobacteria,463Y4@72275|Alteromonadaceae 1236|Gammaproteobacteria S Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis ubiB GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016020,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901576,GO:1901661,GO:1901663 - ko:K03688 - - - - ko00000 - - iYL1228.KPN_04331 ABC1 k141_377_2 1279017.AQYJ01000027_gene1937 1.73e-96 286.0 COG3165@1|root,COG3165@2|Bacteria,1R1CM@1224|Proteobacteria,1S1SM@1236|Gammaproteobacteria,4689F@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria yigP - - ko:K03690 - - - - ko00000 - - - SCP2 k141_3892_1 1121406.JAEX01000005_gene3012 3.56e-67 221.0 COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,42N6C@68525|delta/epsilon subdivisions,2WJ66@28221|Deltaproteobacteria,2M93K@213115|Desulfovibrionales 28221|Deltaproteobacteria G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate gpmI - 5.4.2.12 ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000 - - - Metalloenzyme,Phosphodiest,iPGM_N k141_27553_1 42565.FP66_04245 2.84e-22 91.3 COG1174@1|root,COG1174@2|Bacteria,1MXA1@1224|Proteobacteria,1RQ1F@1236|Gammaproteobacteria 1236|Gammaproteobacteria P transport opuCB - - ko:K05846 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - BPD_transp_1 k141_27553_2 42565.FP66_04240 5.99e-67 213.0 COG0517@1|root,COG1125@1|root,COG0517@2|Bacteria,COG1125@2|Bacteria,1QTUC@1224|Proteobacteria,1RQWQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria E abc transporter atp-binding protein opuBA - - ko:K05847 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - ABC_tran,CBS k141_37059_1 1042377.AFPJ01000036_gene1137 0.0 1145.0 COG1629@1|root,COG1629@2|Bacteria,1MVSG@1224|Proteobacteria,1RS33@1236|Gammaproteobacteria,46A68@72275|Alteromonadaceae 1236|Gammaproteobacteria P Carboxypeptidase regulatory-like domain - - - - - - - - - - - - CarboxypepD_reg k141_32278_1 1042377.AFPJ01000030_gene458 1.84e-43 147.0 COG1057@1|root,COG1057@2|Bacteria,1RD0J@1224|Proteobacteria,1RP00@1236|Gammaproteobacteria,46745@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) nadD GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034355,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043094,GO:0043173,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18,3.5.4.4 ko:K00969,ko:K01488 ko00230,ko00760,ko01100,ko05340,map00230,map00760,map01100,map05340 M00115 R00137,R01560,R02556,R03005 RC00002,RC00477 ko00000,ko00001,ko00002,ko01000 - - iECUMN_1333.ECUMN_0733,iJN746.PP_4810,iPC815.YPO2607,iSbBS512_1146.SbBS512_E0612 CTP_transf_like k141_26574_1 218284.CCDN010000001_gene40 5.87e-91 272.0 COG1162@1|root,COG1162@2|Bacteria,1TPSQ@1239|Firmicutes,4HA9W@91061|Bacilli,1ZB4W@1386|Bacillus 91061|Bacilli S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit rsgA - 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 - R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 - - - RsgA_GTPase,RsgA_N k141_16964_1 218284.CCDN010000005_gene3425 1.31e-96 289.0 COG0492@1|root,COG0492@2|Bacteria,1TRPN@1239|Firmicutes,4H9V7@91061|Bacilli,1ZCEZ@1386|Bacillus 91061|Bacilli C reductase yumC - 1.18.1.2,1.19.1.1 ko:K21567 - - - - ko00000,ko01000 - - iYO844.BSU32110 Pyr_redox_2 k141_31220_2 1535422.ND16A_1680 1.06e-09 58.9 2C87H@1|root,32TKH@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - SnoaL_2 k141_35891_1 218284.CCDN010000002_gene2592 3.04e-91 271.0 COG0745@1|root,COG0745@2|Bacteria,1TQUQ@1239|Firmicutes,4HAXP@91061|Bacilli,1ZD4W@1386|Bacillus 91061|Bacilli T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain yclJ - - ko:K02483 - - - - ko00000,ko02022 - - - Response_reg,Trans_reg_C k141_22895_1 218284.CCDN010000007_gene3870 5.7e-38 134.0 2E2NT@1|root,32XRT@2|Bacteria,1VEBQ@1239|Firmicutes,4HKGD@91061|Bacilli,1ZHTE@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_19281_1 1279017.AQYJ01000027_gene1684 7.98e-204 581.0 COG3850@1|root,COG3850@2|Bacteria,1MWZT@1224|Proteobacteria,1RNPP@1236|Gammaproteobacteria,465S0@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG3850 Signal transduction histidine kinase, nitrate nitrite-specific narQ GO:0000155,GO:0000160,GO:0001101,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010167,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0035556,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070887,GO:0071229,GO:0071241,GO:0071249,GO:0071250,GO:0071704,GO:0071944,GO:0080033,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170 2.7.13.3 ko:K07673,ko:K07674 ko02020,map02020 M00471,M00472 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA_3,PilJ k141_15750_1 218284.CCDN010000001_gene677 5.49e-125 363.0 COG1131@1|root,COG1131@2|Bacteria,1TP4J@1239|Firmicutes,4HBGH@91061|Bacilli,1ZB4N@1386|Bacillus 91061|Bacilli V ABC transporter, ATP-binding protein yhcH - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_15750_2 218284.CCDN010000001_gene678 4.36e-46 158.0 COG1277@1|root,COG1277@2|Bacteria,1TT9E@1239|Firmicutes,4HE5W@91061|Bacilli,1ZDPM@1386|Bacillus 91061|Bacilli S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component yhcI - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_2,ABC2_membrane_4 k141_26575_1 935948.KE386495_gene1239 3.37e-18 85.1 COG0407@1|root,COG0407@2|Bacteria,1UY51@1239|Firmicutes,24DZF@186801|Clostridia,42FW9@68295|Thermoanaerobacterales 186801|Clostridia H PFAM Uroporphyrinogen decarboxylase (URO-D) - - - - - - - - - - - - URO-D k141_6336_1 1116375.VEJY3_00090 0.0 1342.0 COG0366@1|root,COG0366@2|Bacteria,1MU90@1224|Proteobacteria,1RQ1S@1236|Gammaproteobacteria,1XURK@135623|Vibrionales 135623|Vibrionales G alpha-amylase malS - 3.2.1.1 ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 - R02108,R02112,R11262 - ko00000,ko00001,ko01000 - GH13 - Alpha-amylase k141_37060_1 1116375.VEJY3_17211 4.64e-89 275.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RQ6F@1236|Gammaproteobacteria,1XUU7@135623|Vibrionales 135623|Vibrionales C belongs to the aldehyde dehydrogenase family - - - ko:K15786 ko00260,map00260 - R09805 RC00080 ko00000,ko00001,ko01000 - - - Aldedh k141_32279_1 218284.CCDN010000002_gene1999 1.83e-52 182.0 COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,4HB12@91061|Bacilli,1ZCM9@1386|Bacillus 91061|Bacilli L ATP-dependent DNA helicase pcrA - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C k141_5007_1 1056820.KB900685_gene2812 2.43e-28 122.0 COG3266@1|root,COG3266@2|Bacteria,1NMZ5@1224|Proteobacteria,1SX8D@1236|Gammaproteobacteria,2PP5X@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria S Domain of unknown function (DUF5011) - - - - - - - - - - - - DUF5011 k141_16965_1 218284.CCDN010000001_gene1940 7.55e-197 558.0 COG4187@1|root,COG4187@2|Bacteria,1TQQ7@1239|Firmicutes,4HABT@91061|Bacilli,1ZCEE@1386|Bacillus 91061|Bacilli E arginine degradation protein rocB - - - - - - - - - - - Peptidase_M20 k141_3895_1 572477.Alvin_3016 6.3e-06 51.6 COG4970@1|root,COG4970@2|Bacteria,1N7RS@1224|Proteobacteria,1SCFB@1236|Gammaproteobacteria,1WYQF@135613|Chromatiales 135613|Chromatiales NU Type II transport protein GspH - - - ko:K08084 - - - - ko00000,ko02044 3.A.15.2 - - GspH,N_methyl k141_1422_1 218284.CCDN010000001_gene1213 1.31e-119 358.0 COG0840@1|root,COG0840@2|Bacteria,1UV22@1239|Firmicutes,4IBKM@91061|Bacilli,1ZERB@1386|Bacillus 91061|Bacilli NT CHASE3 domain - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - CHASE3,MCPsignal k141_31221_1 1385511.N783_09255 1.5e-115 339.0 COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,4HAE3@91061|Bacilli,2Y91F@289201|Pontibacillus 91061|Bacilli E ABC transporter permease braC - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 k141_12569_1 1479235.KK366039_gene2984 1.4e-32 121.0 COG1562@1|root,COG1562@2|Bacteria,1MX4W@1224|Proteobacteria,1RRNH@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Phytoene squalene synthetase crtB GO:0003674,GO:0003824,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016108,GO:0016109,GO:0016114,GO:0016116,GO:0016117,GO:0016740,GO:0016765,GO:0042440,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046148,GO:0071704,GO:1901576 2.5.1.32,2.5.1.99 ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 M00097 R02065,R04218,R07270,R10177 RC00362,RC01101,RC02869 ko00000,ko00001,ko00002,ko01000,ko01006 - - - SQS_PSY k141_12569_2 1479235.KK366039_gene2985 5.3e-142 412.0 COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,1RMGJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q COG1233 Phytoene dehydrogenase and related proteins crtI - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 ko:K10027 ko00906,ko01100,ko01110,map00906,map01100,map01110 - R04787,R04798,R04800,R09691,R09692 RC01214,RC02088,RC02605 ko00000,ko00001,ko01000 - - - Amino_oxidase k141_20661_2 997296.PB1_08327 1.79e-67 220.0 29H5Q@1|root,30439@2|Bacteria,1V63Q@1239|Firmicutes,4HHR2@91061|Bacilli,1ZE9T@1386|Bacillus 91061|Bacilli S Nuclease-related domain - - - - - - - - - - - - NERD k141_36055_1 290398.Csal_2357 3.03e-102 303.0 COG1732@1|root,COG1732@2|Bacteria,1MV9N@1224|Proteobacteria,1RN72@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) - - - ko:K05845 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - OpuAC k141_10096_1 941824.TCEL_01644 7.64e-68 216.0 COG1210@1|root,COG1210@2|Bacteria,1TQ24@1239|Firmicutes,25E5A@186801|Clostridia,36EIH@31979|Clostridiaceae 186801|Clostridia M UTP-glucose-1-phosphate uridylyltransferase galU - 2.7.7.9 ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 M00129,M00361,M00362,M00549 R00289 RC00002 ko00000,ko00001,ko00002,ko01000 - - iHN637.CLJU_RS02205 NTP_transferase k141_21892_1 1124780.ANNU01000025_gene3325 6.53e-85 265.0 COG2312@1|root,COG2312@2|Bacteria,4NF9R@976|Bacteroidetes,47KA6@768503|Cytophagia 976|Bacteroidetes S Erythromycin esterase - - - ko:K06880 - - - - ko00000,ko01000,ko01504 - - - Erythro_esteras k141_20662_1 1403313.AXBR01000018_gene3419 5.75e-05 45.1 COG0277@1|root,COG0277@2|Bacteria,1UIU4@1239|Firmicutes,4HBGZ@91061|Bacilli,1ZD7D@1386|Bacillus 91061|Bacilli C D-arabinono-1,4-lactone oxidase yitY - - - - - - - - - - - ALO,FAD_binding_4 k141_20662_2 1295642.H839_08689 4.35e-45 152.0 COG2271@1|root,COG2271@2|Bacteria,1TT4P@1239|Firmicutes,4HDSQ@91061|Bacilli,1WH6Y@129337|Geobacillus 91061|Bacilli G Major Facilitator Superfamily yitZ GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - MFS_1 k141_19531_1 42565.FP66_07350 3.38e-115 338.0 COG0624@1|root,COG0624@2|Bacteria,1MW6G@1224|Proteobacteria,1RMNQ@1236|Gammaproteobacteria,1XH2P@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls dapE - 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20 k141_17113_1 935836.JAEL01000062_gene2112 5.57e-84 261.0 COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TP5X@1239|Firmicutes,4H9KS@91061|Bacilli,1ZE6P@1386|Bacillus 91061|Bacilli G phosphotransferase system ybbF GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563,GO:0090588 2.7.1.211 ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 M00269 R00811 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.1,4.A.1.2.10,4.A.1.2.12,4.A.1.2.9 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC k141_23215_1 1220589.CD32_09575 6.93e-118 355.0 COG3509@1|root,COG5184@1|root,COG3509@2|Bacteria,COG5184@2|Bacteria,1UZP5@1239|Firmicutes,4HAWI@91061|Bacilli 91061|Bacilli Q Esterase PHB depolymerase - - - - - - - - - - - - CHB_HEX_C_1,Esterase_phd k141_13740_1 218284.CCDN010000005_gene3194 6.77e-136 395.0 COG1232@1|root,COG1232@2|Bacteria,1TQ6W@1239|Firmicutes,4HAUG@91061|Bacilli,1ZANK@1386|Bacillus 91061|Bacilli H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX hemY - 1.3.3.15,1.3.3.4 ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03222,R04178 RC00885 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS09325 Amino_oxidase k141_25568_1 1243664.CAVL020000054_gene3013 5.24e-47 160.0 2E9AZ@1|root,333IU@2|Bacteria,1VGQF@1239|Firmicutes,4HQBT@91061|Bacilli,1ZH89@1386|Bacillus 91061|Bacilli S Phage tail protein - - - - - - - - - - - - Sipho_tail k141_14703_1 218284.CCDN010000006_gene3679 4.01e-79 250.0 COG4942@1|root,COG4942@2|Bacteria,1TQ5I@1239|Firmicutes,4HB9Q@91061|Bacilli,1ZBKA@1386|Bacillus 91061|Bacilli D peptidase - - - ko:K21471 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_M23 k141_26886_1 218284.CCDN010000002_gene2266 4.75e-110 330.0 COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,1TPXQ@1239|Firmicutes,4HA3C@91061|Bacilli,1ZBHE@1386|Bacillus 91061|Bacilli C Catalyzes the reversible hydration of fumarate to (S)- malate fumA - 4.2.1.2 ko:K01676 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - - Fumerase,Fumerase_C k141_37281_1 1385514.N782_19525 5.81e-35 129.0 COG3264@1|root,COG3264@2|Bacteria,1UIZT@1239|Firmicutes,4HCE1@91061|Bacilli,2YBAR@289201|Pontibacillus 91061|Bacilli M Mechanosensitive ion channel - - - ko:K05802,ko:K22051 - - - - ko00000,ko02000 1.A.23.1.1,1.A.23.1.2,1.A.23.1.3 - - MS_channel k141_11277_1 996637.SGM_2908 0.00019 49.7 COG4264@1|root,COG4264@2|Bacteria,2GMS0@201174|Actinobacteria 201174|Actinobacteria Q IucA IucC family protein alcC - - - - - - - - - - - Acetyltransf_8,FhuF,IucA_IucC k141_18430_1 218284.CCDN010000007_gene3937 2.68e-69 216.0 COG0095@1|root,COG0095@2|Bacteria,1TQKA@1239|Firmicutes,4HCPS@91061|Bacilli,1ZCIA@1386|Bacillus 91061|Bacilli H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes lipL GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.3.1.200,2.3.1.204 ko:K16869,ko:K18821 - - - - ko00000,ko01000 - - - BPL_LplA_LipB k141_13741_1 218284.CCDN010000001_gene7 3.09e-67 210.0 COG0758@1|root,COG0758@2|Bacteria,1TPP7@1239|Firmicutes,4HGWM@91061|Bacilli,1ZBZ3@1386|Bacillus 91061|Bacilli LU Rossmann fold nucleotide-binding protein involved in DNA uptake dprA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0007154,GO:0008150,GO:0009292,GO:0009294,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0044424,GO:0044464,GO:0044764,GO:0050896,GO:0051704,GO:0051716,GO:0071496 - ko:K04096 - - - - ko00000 - - - DNA_processg_A k141_12583_1 1382315.JPOI01000001_gene2511 8.34e-81 256.0 COG1586@1|root,COG4262@1|root,COG1586@2|Bacteria,COG4262@2|Bacteria,1UHSI@1239|Firmicutes,4HAWQ@91061|Bacilli,1WFUP@129337|Geobacillus 91061|Bacilli E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - 2.5.1.16 ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 M00034,M00133 R01920,R02869,R08359 RC00021,RC00053 ko00000,ko00001,ko00002,ko01000 - - - AdoMet_dc,Spermine_synth k141_19560_1 1294265.JCM21738_1610 1.37e-98 293.0 COG1173@1|root,COG1173@2|Bacteria,1V21B@1239|Firmicutes,4HDPU@91061|Bacilli,1ZEQ7@1386|Bacillus 91061|Bacilli EP Binding-protein-dependent transport system inner membrane component - - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1,Peptidase_M1 k141_20674_1 1535422.ND16A_1446 2.68e-76 244.0 COG1835@1|root,COG1835@2|Bacteria,1RHQR@1224|Proteobacteria,1S8IU@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Acyltransferase family - - - - - - - - - - - - Acyl_transf_3 k141_1633_1 218284.CCDN010000003_gene2989 0.0 945.0 COG1197@1|root,COG1197@2|Bacteria,1TPF1@1239|Firmicutes,4H9NB@91061|Bacilli,1ZBAK@1386|Bacillus 91061|Bacilli L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd - - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF k141_10124_1 218284.CCDN010000001_gene132 3.76e-153 462.0 COG1038@1|root,COG1038@2|Bacteria,1UHP9@1239|Firmicutes,4IS56@91061|Bacilli,1ZC4R@1386|Bacillus 91061|Bacilli C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second pyc - 6.4.1.1 ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 M00173 R00344 RC00040,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,HMGL-like,PYC_OADA k141_24246_1 1307436.PBF_08823 6.9e-70 224.0 COG3595@1|root,COG3595@2|Bacteria,1V94C@1239|Firmicutes,4HJYP@91061|Bacilli,1ZEE4@1386|Bacillus 91061|Bacilli S Putative adhesin liaG - - ko:K11621 ko02020,map02020 - - - ko00000,ko00001 - - - DUF4097 k141_32479_2 1453501.JELR01000002_gene131 1.29e-76 235.0 COG2197@1|root,COG2197@2|Bacteria,1P4TD@1224|Proteobacteria,1RU35@1236|Gammaproteobacteria,466GT@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain tcsR - - - - - - - - - - - GerE,Response_reg k141_30116_2 314292.VAS14_03603 2.82e-194 544.0 COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,1RMAQ@1236|Gammaproteobacteria,1XVPF@135623|Vibrionales 135623|Vibrionales L COG3547 Transposase and inactivated derivatives - - - - - - - - - - - - DEDD_Tnp_IS110,Transposase_20 k141_30116_3 313612.L8106_17952 1.31e-27 111.0 COG1403@1|root,COG1403@2|Bacteria,1GAK5@1117|Cyanobacteria,1HDWV@1150|Oscillatoriales 1117|Cyanobacteria V HNH endonuclease - - - - - - - - - - - - HNH_2 k141_4145_2 1453501.JELR01000001_gene3250 5.29e-284 783.0 COG4784@1|root,COG4784@2|Bacteria,1QTT7@1224|Proteobacteria,1RSQ1@1236|Gammaproteobacteria,46CNY@72275|Alteromonadaceae 1236|Gammaproteobacteria S Peptidase family M48 - - - - - - - - - - - - Peptidase_M48 k141_4145_3 1279017.AQYJ01000022_gene2604 5.16e-312 859.0 COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,1RMGS@1236|Gammaproteobacteria,46625@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II alkK - 6.2.1.44 ko:K20034 ko00920,map00920 - R10820 RC00004,RC00014 ko00000,ko00001,ko01000 - - - AMP-binding,AMP-binding_C k141_4145_4 1279017.AQYJ01000022_gene2603 4.41e-46 160.0 COG0584@1|root,COG0584@2|Bacteria,1MVWZ@1224|Proteobacteria,1RRBP@1236|Gammaproteobacteria,464IE@72275|Alteromonadaceae 1236|Gammaproteobacteria C Glycerophosphoryl diester phosphodiesterase family glpQ GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0008081,GO:0008889,GO:0009279,GO:0016020,GO:0016787,GO:0016788,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0042578,GO:0042597,GO:0043167,GO:0043169,GO:0044462,GO:0044464,GO:0046872,GO:0071944 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - iECNA114_1301.ECNA114_2331,iECSF_1327.ECSF_2119 GDPD k141_29015_1 1304880.JAGB01000002_gene2050 3.46e-27 106.0 COG1555@1|root,COG1555@2|Bacteria,1VA3W@1239|Firmicutes,24MQF@186801|Clostridia 186801|Clostridia L TIGRFAM Competence protein ComEA, helix-hairpin-helix comEA - - ko:K02237 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - HHH_3,SLBB k141_5339_1 223926.28807796 7.65e-73 222.0 COG2249@1|root,COG2249@2|Bacteria,1MXFT@1224|Proteobacteria,1RMVS@1236|Gammaproteobacteria,1XTQK@135623|Vibrionales 135623|Vibrionales C Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefB kefG - - ko:K11748 - - - - ko00000,ko02000 2.A.37.1.2 - - Flavodoxin_2 k141_5339_2 1219077.VAZ01S_063_00160 0.0 1099.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPES@1236|Gammaproteobacteria,1XU1H@135623|Vibrionales 135623|Vibrionales S COG0488 ATPase components of ABC transporters with duplicated ATPase domains yheS - - ko:K06158 - - - - ko00000,ko03012 - - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn,CENP-O k141_5339_3 1116375.VEJY3_14245 8.61e-111 318.0 COG5589@1|root,COG5589@2|Bacteria,1NGHI@1224|Proteobacteria,1SGFT@1236|Gammaproteobacteria,1XT79@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF2390) - - - - - - - - - - - - DUF2390 k141_5339_4 1116375.VEJY3_14250 2.34e-231 638.0 COG0429@1|root,COG0429@2|Bacteria,1MWV1@1224|Proteobacteria,1RN39@1236|Gammaproteobacteria,1XT1I@135623|Vibrionales 135623|Vibrionales S hydrolase of the alpha beta-hydrolase fold yheT - - ko:K07019 - - - - ko00000 - - - Abhydrolase_1 k141_5339_5 1219076.N646_1883 3.26e-38 128.0 COG3089@1|root,COG3089@2|Bacteria,1N6TM@1224|Proteobacteria,1SCDE@1236|Gammaproteobacteria,1XYYU@135623|Vibrionales 135623|Vibrionales S Belongs to the UPF0270 family - - - ko:K09898 - - - - ko00000 - - - UPF0270 k141_5339_6 1280001.BAOA01000039_gene2505 5.68e-137 391.0 COG3954@1|root,COG3954@2|Bacteria,1MWN9@1224|Proteobacteria,1RMS7@1236|Gammaproteobacteria,1XSST@135623|Vibrionales 135623|Vibrionales G Phosphoribulokinase prkB - 2.7.1.19 ko:K00855 ko00710,ko01100,ko01120,ko01200,map00710,map01100,map01120,map01200 M00165,M00166 R01523 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - PRK k141_26888_2 218284.CCDN010000001_gene8 3.68e-177 496.0 COG0074@1|root,COG0074@2|Bacteria,1TPIT@1239|Firmicutes,4HA2J@91061|Bacilli,1ZCHE@1386|Bacillus 91061|Bacilli C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit sucD - 6.2.1.5 ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU16100 CoA_binding,Ligase_CoA k141_6504_1 2340.JV46_23630 1.36e-93 285.0 COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,1RN4I@1236|Gammaproteobacteria,1J54M@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) aroB GO:0000166,GO:0003674,GO:0003824,GO:0003856,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0051287,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.4 ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03083 RC00847 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b3389,iBWG_1329.BWG_3080,iECDH10B_1368.ECDH10B_3564,iECDH1ME8569_1439.ECDH1ME8569_3268,iECNA114_1301.ECNA114_3486,iEcDH1_1363.EcDH1_0324,iJO1366.b3389,iJR904.b3389,iY75_1357.Y75_RS20275 DHQ_synthase k141_11280_1 218284.CCDN010000009_gene4320 2.24e-111 329.0 COG0477@1|root,COG2814@2|Bacteria,1TS3C@1239|Firmicutes,4HC3B@91061|Bacilli,1ZS79@1386|Bacillus 91061|Bacilli EGP Nucleoside H+ symporter ywbF - - ko:K05820 - - - - ko00000,ko02000 2.A.1.27 - - MFS_1_like k141_37285_1 1453501.JELR01000002_gene1473 3.88e-87 262.0 COG1385@1|root,COG1385@2|Bacteria,1MXCU@1224|Proteobacteria,1RPBN@1236|Gammaproteobacteria,466M1@72275|Alteromonadaceae 1236|Gammaproteobacteria J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit rsmE GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.193 ko:K09761 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_RNA k141_36066_1 1279017.AQYJ01000026_gene42 1.1e-80 252.0 COG1748@1|root,COG1748@2|Bacteria,1N22C@1224|Proteobacteria,1RXXV@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Saccharopine dehydrogenase - - - - - - - - - - - - Sacchrp_dh_NADP k141_27709_2 218284.CCDN010000001_gene42 1.73e-19 84.7 COG0631@1|root,COG0631@2|Bacteria,1V6K5@1239|Firmicutes,4HCDR@91061|Bacilli,1ZCYC@1386|Bacillus 91061|Bacilli T phosphatase stp - 3.1.3.16 ko:K20074 - - - - ko00000,ko01000,ko01009 - - - PP2C,PP2C_2 k141_19561_1 1279017.AQYJ01000026_gene106 1.48e-44 149.0 COG3453@1|root,COG3453@2|Bacteria,1N9AF@1224|Proteobacteria,1T4JK@1236|Gammaproteobacteria,46D8N@72275|Alteromonadaceae 1236|Gammaproteobacteria S Putative phosphatase (DUF442) - - 1.8.5.4 ko:K17218 ko00920,map00920 - R10152 RC03155 ko00000,ko00001,ko01000 - - - DUF442 k141_20677_1 1307436.PBF_04928 8.09e-40 142.0 COG1388@1|root,COG1388@2|Bacteria,1V10C@1239|Firmicutes,4IJZY@91061|Bacilli,1ZEW6@1386|Bacillus 91061|Bacilli M COG1388 FOG LysM repeat - - - ko:K19220,ko:K19224 - - - - ko00000,ko01000,ko01002,ko01011 - CBM50 - LysM k141_23220_1 221109.22775915 5.24e-71 224.0 COG1404@1|root,COG1404@2|Bacteria 2|Bacteria O Belongs to the peptidase S8 family - - - - - - - - - - - - Big_5,FIVAR,FlgD_ig,Glyco_hydro_16,HemolysinCabind,Inhibitor_I9,PPC,Peptidase_S8,SLH,fn3_5 k141_18431_1 42565.FP66_06525 5.09e-62 195.0 COG0092@1|root,COG0092@2|Bacteria,1MUAI@1224|Proteobacteria,1RN0P@1236|Gammaproteobacteria,1XHGE@135619|Oceanospirillales 135619|Oceanospirillales J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation rpsC - - ko:K02982 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KH_2,Ribosomal_S3_C k141_18431_3 42565.FP66_06535 1.48e-31 110.0 COG0255@1|root,COG0255@2|Bacteria,1N6PR@1224|Proteobacteria,1SCBN@1236|Gammaproteobacteria,1XM6U@135619|Oceanospirillales 135619|Oceanospirillales J Belongs to the universal ribosomal protein uL29 family rpmC - - ko:K02904 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L29 k141_18431_4 42565.FP66_06540 3.76e-51 162.0 COG0186@1|root,COG0186@2|Bacteria,1MZIK@1224|Proteobacteria,1S8SS@1236|Gammaproteobacteria,1XKR2@135619|Oceanospirillales 135619|Oceanospirillales J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA rpsQ - - ko:K02961 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S17 k141_18431_5 42565.FP66_06545 1.42e-79 236.0 COG0093@1|root,COG0093@2|Bacteria,1RCWZ@1224|Proteobacteria,1S3Z3@1236|Gammaproteobacteria,1XJIX@135619|Oceanospirillales 135619|Oceanospirillales J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome rplN - - ko:K02874 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L14 k141_18431_6 42565.FP66_06550 1.15e-21 86.3 COG0198@1|root,COG0198@2|Bacteria,1MZQD@1224|Proteobacteria,1S973@1236|Gammaproteobacteria,1XKGV@135619|Oceanospirillales 135619|Oceanospirillales J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit rplX - - ko:K02895 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KOW,ribosomal_L24 k141_5340_1 218284.CCDN010000004_gene3145 2.94e-49 167.0 COG2508@1|root,COG2508@2|Bacteria,1V649@1239|Firmicutes,4HHCD@91061|Bacilli,1ZH98@1386|Bacillus 91061|Bacilli QT PucR C-terminal helix-turn-helix domain lrp - - - - - - - - - - - HTH_30 k141_5340_2 218284.CCDN010000004_gene3146 9.99e-47 150.0 COG1937@1|root,COG1937@2|Bacteria,1VFB9@1239|Firmicutes,4HNVQ@91061|Bacilli,1ZHTP@1386|Bacillus 91061|Bacilli S protein conserved in bacteria yrkD - - - - - - - - - - - Trns_repr_metal k141_13742_1 1116375.VEJY3_24321 5.57e-257 709.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1XUXU@135623|Vibrionales 135623|Vibrionales T Bacterial regulatory protein, Fis family - - - ko:K10126 ko02020,map02020 M00504 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activ_2 k141_13742_2 1116375.VEJY3_24316 2.14e-48 170.0 COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RQIN@1236|Gammaproteobacteria,1XTW1@135623|Vibrionales 135623|Vibrionales T COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system VVA1649 - 2.7.13.3 ko:K10125 ko02020,map02020 M00504 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,dCache_1 k141_11281_1 1174504.AJTN02000180_gene1981 4.08e-29 117.0 COG0075@1|root,COG3916@1|root,COG0075@2|Bacteria,COG3916@2|Bacteria,1TR3I@1239|Firmicutes,4HA6W@91061|Bacilli,1ZAT2@1386|Bacillus 91061|Bacilli E Aminotransferase class-V - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10,Acetyltransf_5,Acetyltransf_9,Aminotran_5 k141_26889_1 218284.CCDN010000001_gene92 1.34e-98 293.0 COG0275@1|root,COG0275@2|Bacteria,1TNZV@1239|Firmicutes,4H9U2@91061|Bacilli,1ZCHN@1386|Bacillus 91061|Bacilli J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA rsmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 ko:K03438 - - - - ko00000,ko01000,ko03009 - - - Methyltransf_5 k141_26889_2 218284.CCDN010000001_gene91 1.94e-51 165.0 COG4839@1|root,COG4839@2|Bacteria,1VDUV@1239|Firmicutes,4HKM7@91061|Bacilli,1ZIVC@1386|Bacillus 91061|Bacilli D Essential cell division protein ftsL - - - - - - - - - - - DivIC k141_10127_1 218284.CCDN010000007_gene4030 4.36e-95 302.0 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,4HAIF@91061|Bacilli,1ZBZT@1386|Bacillus 91061|Bacilli L COG0553 Superfamily II DNA RNA helicases, SNF2 family ywqA - - - - - - - - - - - DUF3670,Helicase_C,SNF2_N k141_5341_1 1392838.AWNM01000008_gene1415 1.38e-08 59.7 COG1309@1|root,COG1309@2|Bacteria,1R9P8@1224|Proteobacteria,2WEI1@28216|Betaproteobacteria,3T9AD@506|Alcaligenaceae 28216|Betaproteobacteria K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N k141_13743_1 218284.CCDN010000001_gene685 5.97e-128 386.0 COG0507@1|root,COG0507@2|Bacteria,1TPZH@1239|Firmicutes,4HATQ@91061|Bacilli,1ZAYS@1386|Bacillus 91061|Bacilli L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity recD2 - 3.1.11.5 ko:K03581 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_30,HHH_4,HHH_5,UvrD_C_2 k141_10128_1 218284.CCDN010000002_gene2732 6.37e-111 327.0 COG0246@1|root,COG0246@2|Bacteria,1TPZU@1239|Firmicutes,4H9S3@91061|Bacilli,1ZD4H@1386|Bacillus 91061|Bacilli G COG0246 Mannitol-1-phosphate altronate dehydrogenases mtlD GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006059,GO:0006066,GO:0008150,GO:0008152,GO:0008926,GO:0009056,GO:0009987,GO:0016052,GO:0016491,GO:0016614,GO:0016616,GO:0019400,GO:0019405,GO:0019407,GO:0019592,GO:0019594,GO:0019751,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046164,GO:0046174,GO:0055114,GO:0071704,GO:1901575,GO:1901615,GO:1901616 1.1.1.17 ko:K00009 ko00051,map00051 - R02703 RC00085 ko00000,ko00001,ko01000 - - - Mannitol_dh,Mannitol_dh_C k141_1636_1 663278.Ethha_2283 1.09e-13 74.7 COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,247W3@186801|Clostridia,3WH8B@541000|Ruminococcaceae 186801|Clostridia L Participates in initiation and elongation during chromosome replication dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k141_20679_1 1131730.BAVI_24908 1.83e-83 258.0 2C6FM@1|root,2ZB1N@2|Bacteria,1UTIP@1239|Firmicutes,4HJJE@91061|Bacilli,1ZMFU@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_7585_1 1279017.AQYJ01000029_gene3841 1.17e-14 73.2 COG0007@1|root,COG1648@1|root,COG0007@2|Bacteria,COG1648@2|Bacteria,1MUI0@1224|Proteobacteria,1RM9V@1236|Gammaproteobacteria,4645Q@72275|Alteromonadaceae 1236|Gammaproteobacteria H Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme cysG - 1.3.1.76,2.1.1.107,4.99.1.4 ko:K02302,ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02864,R03194,R03947 RC00003,RC00871,RC01012,RC01034 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_3999 CysG_dimeriser,NAD_binding_7,Sirohm_synth_M,TP_methylase k141_7585_2 1453501.JELR01000001_gene2314 1.13e-38 130.0 2ETJP@1|root,33M3F@2|Bacteria,1NH39@1224|Proteobacteria,1SGTE@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_7585_3 1042377.AFPJ01000007_gene1789 6.85e-150 446.0 COG2366@1|root,COG2366@2|Bacteria,1MVMH@1224|Proteobacteria,1RPRP@1236|Gammaproteobacteria,464U8@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG2366 Protein related to penicillin acylase quiP - 3.5.1.11,3.5.1.97 ko:K01434,ko:K07116 ko00311,ko01130,map00311,map01130 - R02170 RC00166,RC00328 ko00000,ko00001,ko01000,ko01002 - - - Penicil_amidase k141_11283_1 218284.CCDN010000006_gene3588 1.06e-47 167.0 COG1396@1|root,COG1396@2|Bacteria 2|Bacteria K sequence-specific DNA binding - - - ko:K18830 - - - - ko00000,ko02048,ko03000 - - - HTH_19,HTH_3 k141_13744_2 1279017.AQYJ01000027_gene1982 5.74e-15 75.5 COG4206@1|root,COG4206@2|Bacteria,1MUZG@1224|Proteobacteria,1RP7I@1236|Gammaproteobacteria,463Z2@72275|Alteromonadaceae 1236|Gammaproteobacteria H COG1629 Outer membrane receptor proteins, mostly Fe transport - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - CarboxypepD_reg,Plug,TonB_dep_Rec k141_23223_1 218284.CCDN010000010_gene4329 3.43e-22 93.2 COG0489@1|root,COG0489@2|Bacteria,1TQ34@1239|Firmicutes,4HAW4@91061|Bacilli,1ZC2E@1386|Bacillus 91061|Bacilli D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP mrp GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K03593 - - - - ko00000,ko03029,ko03036 - - - FeS_assembly_P,ParA k141_23223_2 218284.CCDN010000010_gene4330 8.01e-44 148.0 COG0860@1|root,COG0860@2|Bacteria,1TQ74@1239|Firmicutes,4HAV3@91061|Bacilli,1ZBJ8@1386|Bacillus 91061|Bacilli M n-acetylmuramoyl-L-alanine amidase cwlD GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - Amidase_3 k141_10129_1 1144310.PMI07_005867 4.47e-07 55.5 COG4221@1|root,COG4221@2|Bacteria,1MV0A@1224|Proteobacteria,2TRAN@28211|Alphaproteobacteria,4BBJN@82115|Rhizobiaceae 28211|Alphaproteobacteria S COG4221 Short-chain alcohol dehydrogenase of rbtD - 1.1.1.56 ko:K00039 ko00040,ko01100,map00040,map01100 - R01895 RC00102 ko00000,ko00001,ko01000 - - - adh_short k141_20680_1 42565.FP66_13375 1.24e-42 140.0 COG1534@1|root,COG1534@2|Bacteria,1N8K5@1224|Proteobacteria,1SDIM@1236|Gammaproteobacteria,1XKKN@135619|Oceanospirillales 135619|Oceanospirillales J RNA-binding protein containing KH domain, possibly ribosomal protein yhbY - - ko:K07574 - - - - ko00000,ko03009 - - - CRS1_YhbY k141_20680_2 42565.FP66_13380 2.71e-21 88.6 COG0293@1|root,COG0293@2|Bacteria,1MW1C@1224|Proteobacteria,1RN5M@1236|Gammaproteobacteria,1XHHV@135619|Oceanospirillales 135619|Oceanospirillales J Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit ftsJ - 2.1.1.166 ko:K02427 - - - - ko00000,ko01000,ko03009 - - - FtsJ k141_25570_1 218284.CCDN010000001_gene1851 9.09e-231 647.0 COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1TSSC@1239|Firmicutes,4HA8C@91061|Bacilli,1ZBA6@1386|Bacillus 91061|Bacilli C COG1014 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, gamma subunit korA - 1.2.7.11,1.2.7.3 ko:K00174 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - PFOR_II,POR,POR_N k141_25570_2 218284.CCDN010000001_gene1852 2.45e-182 512.0 COG2355@1|root,COG2355@2|Bacteria,1UA7M@1239|Firmicutes,4HBJD@91061|Bacilli,1ZDBQ@1386|Bacillus 91061|Bacilli E COG2355 Zn-dependent dipeptidase, microsomal dipeptidase homolog - - 3.4.13.19 ko:K01273 - - - - ko00000,ko00537,ko01000,ko01002,ko04147 - - - Peptidase_M19 k141_25570_3 406124.ACPC01000013_gene907 6.2e-48 154.0 COG2359@1|root,COG2359@2|Bacteria,1V6G8@1239|Firmicutes,4HIQV@91061|Bacilli,1ZH05@1386|Bacillus 91061|Bacilli S Stage V sporulation protein S spoVS - - ko:K06416 - - - - ko00000 - - - SpoVS k141_15961_2 981383.AEWH01000008_gene3638 1.02e-06 47.8 2DR5F@1|root,33A90@2|Bacteria,1VK5I@1239|Firmicutes,4HRSZ@91061|Bacilli 91061|Bacilli S YvrJ protein family - - - - - - - - - - - - YvrJ k141_15961_3 218284.CCDN010000007_gene3916 1e-66 207.0 COG0860@1|root,COG0860@2|Bacteria,1V3MD@1239|Firmicutes,4HHD1@91061|Bacilli,1ZBPF@1386|Bacillus 91061|Bacilli M n-acetylmuramoyl-L-alanine amidase cwlC - 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - Amidase_3,PG_binding_1,SPOR k141_20715_1 985665.HPL003_21270 3.02e-49 177.0 COG1554@1|root,COG1554@2|Bacteria,1TPKN@1239|Firmicutes,4HCCF@91061|Bacilli,26QVY@186822|Paenibacillaceae 91061|Bacilli G alpha-L-fucosidase - - 3.2.1.51 ko:K15923 ko00511,map00511 - - - ko00000,ko00001,ko01000 - GH95 - Glyco_hyd_65N_2 k141_2865_1 218284.CCDN010000002_gene2761 2.9e-104 307.0 COG0775@1|root,COG0775@2|Bacteria,1TSB7@1239|Firmicutes,4HDEM@91061|Bacilli,1ZAYM@1386|Bacillus 91061|Bacilli F Phosphorylase superfamily - - 3.2.2.9 ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 M00034,M00609 R00194,R01401 RC00063,RC00318 ko00000,ko00001,ko00002,ko01000 - - - Cu_amine_oxidN1,PNP_UDP_1 k141_683_1 1121939.L861_20910 1.8e-158 451.0 COG0543@1|root,COG1018@1|root,COG0543@2|Bacteria,COG1018@2|Bacteria,1MV72@1224|Proteobacteria,1RN9X@1236|Gammaproteobacteria,1XK7T@135619|Oceanospirillales 135619|Oceanospirillales C Oxidoreductase FAD-binding domain - - - ko:K05784 ko00362,ko00364,ko00622,ko01100,ko01120,ko01220,map00362,map00364,map00622,map01100,map01120,map01220 M00551 R05290,R05291,R05428,R05621,R05622,R05665,R08100,R08101,R08108,R08109,R08110 RC00270,RC01378,RC01450,RC01910 br01602,ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_6,Fer2,NAD_binding_1 k141_5378_1 42565.FP66_05910 3.36e-114 337.0 COG0665@1|root,COG0665@2|Bacteria,1MVIZ@1224|Proteobacteria,1RQ50@1236|Gammaproteobacteria,1XIS7@135619|Oceanospirillales 135619|Oceanospirillales E D-amino acid dehydrogenase dadA - 1.4.5.1 ko:K00285 ko00360,map00360 - R01374,R09493 RC00006,RC00025 ko00000,ko00001,ko01000 - - - DAO k141_14729_1 1116375.VEJY3_17061 3.96e-92 280.0 COG3748@1|root,COG3748@2|Bacteria,1MWHB@1224|Proteobacteria,1RRV4@1236|Gammaproteobacteria,1XUPI@135623|Vibrionales 135623|Vibrionales S Urate oxidase N-terminal - - - - - - - - - - - - Urate_ox_N k141_14729_2 1116375.VEJY3_17056 1.14e-287 791.0 COG2233@1|root,COG2233@2|Bacteria,1MUN9@1224|Proteobacteria,1RMGW@1236|Gammaproteobacteria,1XUCK@135623|Vibrionales 135623|Vibrionales F COG2233 Xanthine uracil permeases - - - ko:K16345 - - - - ko00000,ko02000 2.A.40.4.2 - - Xan_ur_permease k141_23249_1 441769.ABFU01000018_gene3636 8.56e-33 114.0 2BX75@1|root,32YCI@2|Bacteria,1VEDY@1239|Firmicutes,4HNHZ@91061|Bacilli,1ZIWS@1386|Bacillus 91061|Bacilli S spore protein - - - ko:K06419 - - - - ko00000 - - - SASP k141_26928_1 1297742.A176_05230 1.66e-29 122.0 COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,42M5C@68525|delta/epsilon subdivisions,2WJ54@28221|Deltaproteobacteria,2YURT@29|Myxococcales 28221|Deltaproteobacteria M Transglycosylase SLT domain mltD2 - - ko:K08307 - - - - ko00000,ko01000,ko01011 - - - LysM,SLT k141_37310_2 1279017.AQYJ01000020_gene1265 1.53e-41 136.0 COG0828@1|root,COG0828@2|Bacteria,1MZCC@1224|Proteobacteria,1S8QZ@1236|Gammaproteobacteria,46825@72275|Alteromonadaceae 1236|Gammaproteobacteria J Ribosomal protein S21 rpsU GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02970 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S21 k141_12614_1 796606.BMMGA3_11195 1.78e-45 149.0 2EAKH@1|root,334P5@2|Bacteria,1VMKG@1239|Firmicutes,4HNTF@91061|Bacilli,1ZIU0@1386|Bacillus 91061|Bacilli S YolD-like protein - - - - - - - - - - - - YolD k141_12614_2 218284.CCDN010000001_gene1021 9.54e-45 144.0 COG3369@1|root,COG3369@2|Bacteria,1VFK3@1239|Firmicutes,4HNHY@91061|Bacilli,1ZIZQ@1386|Bacillus 91061|Bacilli S Iron-binding zinc finger CDGSH type - - - - - - - - - - - - zf-CDGSH k141_12614_3 218284.CCDN010000001_gene1022 4.41e-52 166.0 COG0316@1|root,COG0316@2|Bacteria,1VF4S@1239|Firmicutes,4HRJ8@91061|Bacilli,1ZIAS@1386|Bacillus 91061|Bacilli S Belongs to the HesB IscA family yqkB - - - - - - - - - - - Fe-S_biosyn k141_12614_4 218284.CCDN010000001_gene1023 2.28e-84 258.0 COG3570@1|root,COG3570@2|Bacteria,1V5G9@1239|Firmicutes,4HH9E@91061|Bacilli,1ZFTN@1386|Bacillus 91061|Bacilli V Aminoglycoside/hydroxyurea antibiotic resistance kinase - - 2.7.1.72 ko:K04343 - M00766 R02225 RC00002,RC00078 br01600,ko00000,ko00002,ko01000,ko01504 - - - APH_6_hur k141_11571_1 1294265.JCM21738_4 2.03e-96 287.0 COG0119@1|root,COG0119@2|Bacteria,1TQG3@1239|Firmicutes,4HA1U@91061|Bacilli,1ZC18@1386|Bacillus 91061|Bacilli E Hydroxymethylglutaryl-CoA lyase yngG - 4.1.3.4 ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 M00036,M00088 R01360,R08090 RC00502,RC00503,RC01118,RC01946 ko00000,ko00001,ko00002,ko01000 - - - HMGL-like k141_16160_1 10756.PORTL_BPPH2 2.44e-63 203.0 4QDW3@10239|Viruses 10239|Viruses S Phage Connector (GP10) - GO:0005575,GO:0008150,GO:0016032,GO:0019012,GO:0019028,GO:0019058,GO:0019068,GO:0019072,GO:0019073,GO:0032991,GO:0044403,GO:0044419,GO:0044423,GO:0046729,GO:0046798,GO:0051704 - - - - - - - - - - - k141_17320_1 1453501.JELR01000001_gene1975 1.84e-67 215.0 COG0354@1|root,COG0354@2|Bacteria,1N852@1224|Proteobacteria,1RPWB@1236|Gammaproteobacteria,466QJ@72275|Alteromonadaceae 1236|Gammaproteobacteria S aminomethyltransferase related to GcvT ygfZ GO:0003674,GO:0005488,GO:0005542,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0019842,GO:0022607,GO:0031163,GO:0031406,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0071840,GO:0072341,GO:0097159,GO:1901363 - ko:K06980 - - - - ko00000,ko03016 - - - GCV_T,GCV_T_C k141_19769_2 1279017.AQYJ01000025_gene618 9.31e-203 566.0 COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,1RMMW@1236|Gammaproteobacteria,466D8@72275|Alteromonadaceae 1236|Gammaproteobacteria M Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) lpxK GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008654,GO:0009029,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019637,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0046401,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.7.1.130 ko:K00912 ko00540,ko01100,map00540,map01100 M00060 R04657 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 - - iBWG_1329.BWG_0767,iECDH10B_1368.ECDH10B_0985,iPC815.YPO1396 LpxK k141_19769_3 1279017.AQYJ01000025_gene617 3.15e-145 413.0 COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,1RMAE@1236|Gammaproteobacteria,464GE@72275|Alteromonadaceae 1236|Gammaproteobacteria M Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria kdsB GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005996,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008690,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019294,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046394,GO:0046400,GO:0046401,GO:0046872,GO:0070567,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.7.38 ko:K00979 ko00540,ko01100,map00540,map01100 M00063 R03351,R11396 RC00152,RC00910 ko00000,ko00001,ko00002,ko01000,ko01005 - - iAF1260.b0918,iB21_1397.B21_00929,iBWG_1329.BWG_0770,iECBD_1354.ECBD_2677,iECB_1328.ECB_00922,iECDH10B_1368.ECDH10B_0988,iECDH1ME8569_1439.ECDH1ME8569_0869,iECD_1391.ECD_00922,iETEC_1333.ETEC_0986,iEcDH1_1363.EcDH1_2725,iEcHS_1320.EcHS_A1025,iEcolC_1368.EcolC_2678,iJO1366.b0918,iJR904.b0918,iPC815.YPO1400,iUMNK88_1353.UMNK88_1071,iY75_1357.Y75_RS04770 CTP_transf_3 k141_19769_4 1279017.AQYJ01000025_gene616 4.24e-161 460.0 COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,1RNXK@1236|Gammaproteobacteria,465JA@72275|Alteromonadaceae 1236|Gammaproteobacteria M cell wall formation murB - 1.3.1.98 ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R03191,R03192 RC02639 ko00000,ko00001,ko01000,ko01011 - - - FAD_binding_4,MurB_C k141_19769_5 1121923.GPUN_2566 2.46e-49 167.0 COG3145@1|root,COG3145@2|Bacteria,1RGXU@1224|Proteobacteria,1S6DD@1236|Gammaproteobacteria,4676Q@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG3145 Alkylated DNA repair protein alkB - - - - - - - - - - - 2OG-FeII_Oxy_2 k141_19769_6 1279017.AQYJ01000025_gene615 2.43e-114 332.0 COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,1RQ1J@1236|Gammaproteobacteria,466D5@72275|Alteromonadaceae 1236|Gammaproteobacteria KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain gacA - - ko:K07689 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 M00475 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg k141_19769_7 1279017.AQYJ01000025_gene614 0.0 988.0 COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,1RNGV@1236|Gammaproteobacteria,4644T@72275|Alteromonadaceae 1236|Gammaproteobacteria L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision uvrC GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009380,GO:0009381,GO:0009628,GO:0009987,GO:0016787,GO:0016788,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - ko:K03703 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - GIY-YIG,HHH,HHH_2,HHH_5,UVR,UvrC_HhH_N k141_19769_8 1279017.AQYJ01000025_gene613 3.99e-108 314.0 COG0558@1|root,COG0558@2|Bacteria,1RCZ7@1224|Proteobacteria,1S465@1236|Gammaproteobacteria,4670B@72275|Alteromonadaceae 1236|Gammaproteobacteria I Belongs to the CDP-alcohol phosphatidyltransferase class-I family pgsA GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0031224,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 - R01801,R02030 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 - - iAF1260.b1912,iAPECO1_1312.APECO1_954,iB21_1397.B21_01866,iBWG_1329.BWG_1721,iE2348C_1286.E2348C_2030,iEC042_1314.EC042_2073,iEC55989_1330.EC55989_2132,iECABU_c1320.ECABU_c21710,iECBD_1354.ECBD_1731,iECB_1328.ECB_01877,iECDH10B_1368.ECDH10B_2053,iECDH1ME8569_1439.ECDH1ME8569_1852,iECD_1391.ECD_01877,iECED1_1282.ECED1_2177,iECH74115_1262.ECH74115_2684,iECIAI1_1343.ECIAI1_1996,iECIAI39_1322.ECIAI39_1143,iECNA114_1301.ECNA114_2003,iECO103_1326.ECO103_2168,iECO111_1330.ECO111_2492,iECO26_1355.ECO26_2804,iECOK1_1307.ECOK1_2029,iECP_1309.ECP_1852,iECS88_1305.ECS88_1966,iECSF_1327.ECSF_1764,iECSP_1301.ECSP_2516,iECUMN_1333.ECUMN_2204,iECs_1301.ECs2650,iETEC_1333.ETEC_2020,iEcDH1_1363.EcDH1_1734,iEcE24377_1341.EcE24377A_2145,iEcHS_1320.EcHS_A2010,iEcSMS35_1347.EcSMS35_1271,iEcolC_1368.EcolC_1727,iG2583_1286.G2583_2363,iJO1366.b1912,iJR904.b1912,iLF82_1304.LF82_1635,iNRG857_1313.NRG857_09550,iSDY_1059.SDY_1106,iSSON_1240.SSON_1206,iSbBS512_1146.SbBS512_E1039,iUMN146_1321.UM146_07620,iUMNK88_1353.UMNK88_2386,iUTI89_1310.UTI89_C2113,iY75_1357.Y75_RS10025,iYL1228.KPN_02410,iZ_1308.Z3000,ic_1306.c2325 CDP-OH_P_transf k141_19769_9 768706.Desor_5314 7.51e-29 128.0 COG1404@1|root,COG1404@2|Bacteria,1TQ2M@1239|Firmicutes,24CD5@186801|Clostridia,260VW@186807|Peptococcaceae 186801|Clostridia O Belongs to the peptidase S8 family - - - ko:K13274,ko:K14645 ko02024,map02024 - - - ko00000,ko00001,ko01000,ko01002,ko03110 - - - Big_2,CW_binding_2,Peptidase_S8,SLH k141_19769_10 1121875.KB907550_gene638 4e-176 505.0 COG5361@1|root,COG5361@2|Bacteria,4NKSK@976|Bacteroidetes,1IARY@117743|Flavobacteriia 976|Bacteroidetes S Protein of unknown function (DUF1254) - - - - - - - - - - - - DUF1214,DUF1254 k141_22114_1 1294265.JCM21738_1984 4.98e-95 277.0 COG1495@1|root,COG1495@2|Bacteria,1VAYZ@1239|Firmicutes,4IRN5@91061|Bacilli,1ZRVY@1386|Bacillus 91061|Bacilli O Required for disulfide bond formation in some proteins bdbC - - ko:K03611 - - - - ko00000,ko03110 5.A.2.1 - - DsbB k141_30269_2 1453501.JELR01000005_gene1764 7.21e-212 592.0 COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,1RM7X@1236|Gammaproteobacteria,464V7@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate proB GO:0000287,GO:0003674,GO:0003824,GO:0004349,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019202,GO:0019752,GO:0031406,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0055129,GO:0071704,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901973 2.7.2.11 ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 M00015 R00239 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,PUA k141_30269_3 1279017.AQYJ01000019_gene1492 4.24e-225 627.0 COG0536@1|root,COG0536@2|Bacteria,1MUGZ@1224|Proteobacteria,1RMFQ@1236|Gammaproteobacteria,4647H@72275|Alteromonadaceae 1236|Gammaproteobacteria S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control obg GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0007059,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0022607,GO:0022611,GO:0022613,GO:0022618,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0042254,GO:0042255,GO:0043021,GO:0043023,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0065003,GO:0065007,GO:0070925,GO:0071826,GO:0071840,GO:0090069,GO:0090071,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03979 - - - - ko00000,ko01000,ko03009 - - - GTP1_OBG,MMR_HSR1 k141_18730_1 1279017.AQYJ01000027_gene1950 3.7e-111 327.0 COG0500@1|root,COG0640@1|root,COG0640@2|Bacteria,COG2226@2|Bacteria,1NFSV@1224|Proteobacteria,1RQT6@1236|Gammaproteobacteria,464PH@72275|Alteromonadaceae 1236|Gammaproteobacteria K Transcriptional regulators - - - - - - - - - - - - HTH_20,HTH_5,Methyltransf_11,Methyltransf_23,Methyltransf_31 k141_18730_2 1042377.AFPJ01000032_gene2739 1.6e-271 745.0 COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,1RNV6@1236|Gammaproteobacteria,4642H@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme metK GO:0000096,GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004478,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006556,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009069,GO:0009108,GO:0009116,GO:0009119,GO:0009987,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0019752,GO:0030554,GO:0030955,GO:0031420,GO:0032553,GO:0032555,GO:0032559,GO:0033353,GO:0034641,GO:0035639,GO:0036094,GO:0042278,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0046872,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901576,GO:1901605,GO:1901657 2.5.1.6 ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 M00034,M00035,M00368,M00609 R00177,R04771 RC00021,RC01211 ko00000,ko00001,ko00002,ko01000 - - iYL1228.KPN_03375 S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N k141_4278_1 1294265.JCM21738_4743 4.66e-103 304.0 COG0123@1|root,COG0123@2|Bacteria,1TQF7@1239|Firmicutes,4HBTF@91061|Bacilli,1ZC2K@1386|Bacillus 91061|Bacilli BQ histone deacetylase acuC - - ko:K04768 - - - - ko00000 - - iYO844.BSU29710 Hist_deacetyl k141_7793_1 1453501.JELR01000002_gene55 1.38e-213 650.0 COG2911@1|root,COG2911@2|Bacteria,1MUVD@1224|Proteobacteria 1224|Proteobacteria M Protein conserved in bacteria tamB - - ko:K09800 - - - - ko00000,ko02000 - - - TamB k141_7793_2 1042377.AFPJ01000025_gene594 1.05e-179 516.0 COG0729@1|root,COG0729@2|Bacteria,1MUKM@1224|Proteobacteria,1RNQ3@1236|Gammaproteobacteria,465KK@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0729 Outer membrane protein ytfM - - ko:K07278 - - - - ko00000,ko02000 1.B.33.2.4 - - Bac_surface_Ag,POTRA,POTRA_TamA_1 k141_14039_2 218284.CCDN010000001_gene86 4.68e-214 593.0 COG0472@1|root,COG0472@2|Bacteria,1TP8W@1239|Firmicutes,4H9TP@91061|Bacilli,1ZBIK@1386|Bacillus 91061|Bacilli M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan mraY GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.8.13 ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 - R05629,R05630 RC00002,RC02753 ko00000,ko00001,ko01000,ko01011 9.B.146 - - Glycos_transf_4,MraY_sig1 k141_14039_3 218284.CCDN010000001_gene85 9.03e-149 429.0 COG0771@1|root,COG0771@2|Bacteria,1TQ3P@1239|Firmicutes,4HA5P@91061|Bacilli,1ZARV@1386|Bacillus 91061|Bacilli M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) murD - 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase_C,Mur_ligase_M k141_14915_3 450380.JPSY01000001_gene169 2.3e-25 103.0 COG0031@1|root,COG0031@2|Bacteria,2GIXE@201174|Actinobacteria,4FKBA@85023|Microbacteriaceae 201174|Actinobacteria E Pyridoxal-phosphate dependent enzyme cysK GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03601,R04859 RC00020,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 - - - PALP k141_19770_1 1347368.HG964408_gene7115 7.39e-59 189.0 COG3340@1|root,COG3340@2|Bacteria,1TRBA@1239|Firmicutes,4HB19@91061|Bacilli,1ZC4Z@1386|Bacillus 91061|Bacilli E Belongs to the peptidase S51 family ygaJ GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564 3.4.13.21 ko:K05995 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S51 k141_19770_2 1294265.JCM21738_2926 4.92e-56 180.0 COG0420@1|root,COG0420@2|Bacteria,1TWMI@1239|Firmicutes,4HCA0@91061|Bacilli,1ZC5G@1386|Bacillus 91061|Bacilli L DNA repair exonuclease yhaO - - ko:K03547 - - - - ko00000,ko03400 - - - Metallophos,Metallophos_2 k141_11572_2 658086.HMPREF0994_02834 5.11e-29 115.0 COG0745@1|root,COG0745@2|Bacteria,1TP9M@1239|Firmicutes,247TK@186801|Clostridia,27JF2@186928|unclassified Lachnospiraceae 186801|Clostridia KT Transcriptional regulatory protein, C terminal vanR3 - - - - - - - - - - - Response_reg,Trans_reg_C k141_29227_1 1279017.AQYJ01000021_gene2884 1.52e-131 378.0 COG3637@1|root,COG3637@2|Bacteria,1R3QN@1224|Proteobacteria,1RY3J@1236|Gammaproteobacteria,467AR@72275|Alteromonadaceae 1236|Gammaproteobacteria M Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - - - - - - - - - - - k141_29227_2 1042377.AFPJ01000037_gene3007 5.69e-178 500.0 COG0583@1|root,COG0583@2|Bacteria,1NSNV@1224|Proteobacteria,1RPNG@1236|Gammaproteobacteria,4651F@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG0583 Transcriptional regulator cmpR_1 - - - - - - - - - - - HTH_1,LysR_substrate k141_29227_3 1453501.JELR01000001_gene1827 5.71e-315 862.0 COG0065@1|root,COG0065@2|Bacteria,1MVYR@1224|Proteobacteria,1RMF6@1236|Gammaproteobacteria,4642D@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate leuC - 4.2.1.33,4.2.1.35 ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170 RC00497,RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase k141_29227_4 1453501.JELR01000001_gene1828 1.38e-142 403.0 COG0066@1|root,COG0066@2|Bacteria,1MVXB@1224|Proteobacteria,1RNMK@1236|Gammaproteobacteria,464MP@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate leuD - 4.2.1.33,4.2.1.35 ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R10170 RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase_C k141_29227_5 349106.PsycPRwf_1934 9.5e-07 51.2 COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,1RMZQ@1236|Gammaproteobacteria,3NK2W@468|Moraxellaceae 1236|Gammaproteobacteria CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate leuB GO:0000287,GO:0003674,GO:0003824,GO:0003862,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0030145,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034198,GO:0042594,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114,GO:0071496,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1990928 1.1.1.85 ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R00994,R04426,R10052 RC00084,RC00417,RC03036 br01601,ko00000,ko00001,ko00002,ko01000 - - iECs_1301.ECs0077,iYL1228.KPN_00079,iZ_1308.Z0082 Iso_dh k141_22118_1 1042377.AFPJ01000025_gene594 1.04e-85 269.0 COG0729@1|root,COG0729@2|Bacteria,1MUKM@1224|Proteobacteria,1RNQ3@1236|Gammaproteobacteria,465KK@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0729 Outer membrane protein ytfM - - ko:K07278 - - - - ko00000,ko02000 1.B.33.2.4 - - Bac_surface_Ag,POTRA,POTRA_TamA_1 k141_24534_1 1116375.VEJY3_03240 1.53e-199 551.0 COG5595@1|root,COG5595@2|Bacteria,1NDR3@1224|Proteobacteria,1RRXG@1236|Gammaproteobacteria,1XTPF@135623|Vibrionales 135623|Vibrionales S COG5595 Zn-ribbon-containing, possibly nucleic-acid-binding protein HD1486 - - - - - - - - - - - DUF2310 k141_24534_2 223926.28805688 2.44e-108 314.0 28Q4G@1|root,2ZCMR@2|Bacteria,1RAB3@1224|Proteobacteria,1S2N3@1236|Gammaproteobacteria,1XVSC@135623|Vibrionales 135623|Vibrionales S Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function syd - - ko:K15723 - - - - ko00000 - - - Syd k141_24534_3 223926.28805687 1.02e-195 543.0 COG0780@1|root,COG2904@1|root,COG0780@2|Bacteria,COG2904@2|Bacteria,1MW0M@1224|Proteobacteria,1RNXM@1236|Gammaproteobacteria,1XSYX@135623|Vibrionales 135623|Vibrionales S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) queF - 1.7.1.13 ko:K06879 ko00790,ko01100,map00790,map01100 - R07605 RC01875 ko00000,ko00001,ko01000,ko03016 - - - QueF,QueF_N k141_14917_3 1279017.AQYJ01000026_gene213 4.04e-14 71.6 COG3387@1|root,COG3387@2|Bacteria,1NB01@1224|Proteobacteria,1RS3W@1236|Gammaproteobacteria,46581@72275|Alteromonadaceae 1236|Gammaproteobacteria G PFAM Glycoside hydrolase 15-related - - - - - - - - - - - - Prenyltrans k141_6750_2 1453501.JELR01000002_gene197 1.86e-181 520.0 COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,1RNIT@1236|Gammaproteobacteria,464TD@72275|Alteromonadaceae 1236|Gammaproteobacteria G Belongs to the GPI family pgi GO:0003674,GO:0003824,GO:0004347,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033554,GO:0034404,GO:0034599,GO:0034641,GO:0034654,GO:0034655,GO:0042221,GO:0042802,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0055086,GO:0070887,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 - - iEcSMS35_1347.EcSMS35_4486 PGI k141_35310_1 218284.CCDN010000001_gene1544 7.47e-127 370.0 COG1686@1|root,COG1686@2|Bacteria,1TQN0@1239|Firmicutes,4HBD4@91061|Bacilli,1ZAS6@1386|Bacillus 91061|Bacilli M Belongs to the peptidase S11 family dacA GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0009002,GO:0016787,GO:0017171,GO:0019538,GO:0030312,GO:0043170,GO:0044238,GO:0044464,GO:0070008,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.16.4 ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - PBP5_C,Peptidase_S11 k141_27178_1 1461579.CCNK01000007_gene192 2.62e-18 88.6 COG2265@1|root,COG2265@2|Bacteria,1MV3A@1224|Proteobacteria,1RN1D@1236|Gammaproteobacteria,1Y6WM@135625|Pasteurellales 135625|Pasteurellales J Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA rlmD - 2.1.1.190 ko:K03215 - - - - ko00000,ko01000,ko03009 - - - TRAM,tRNA_U5-meth_tr k141_25863_1 218284.CCDN010000007_gene3954 1.02e-144 426.0 COG0247@1|root,COG2181@1|root,COG0247@2|Bacteria,COG2181@2|Bacteria,1TPG1@1239|Firmicutes,4HB2J@91061|Bacilli,1ZBAJ@1386|Bacillus 91061|Bacilli C COG0247 Fe-S oxidoreductase ywjF - - - - - - - - - - - CCG,Fer4_8 k141_30289_1 1462526.BN990_01044 9.71e-80 252.0 COG0591@1|root,COG0591@2|Bacteria,1TRK6@1239|Firmicutes,4HEE9@91061|Bacilli,4C4V4@84406|Virgibacillus 91061|Bacilli E Sodium:solute symporter family - - - ko:K11928,ko:K14392 - - - - ko00000,ko02000 2.A.21.1,2.A.21.2 - - SSF k141_6751_1 574087.Acear_0497 2.65e-08 58.2 COG0622@1|root,COG0622@2|Bacteria,1VA0U@1239|Firmicutes,24MMK@186801|Clostridia,3WAYI@53433|Halanaerobiales 186801|Clostridia S TIGRFAM phosphoesterase, MJ0936 family yfcE1 - - ko:K07095 - - - - ko00000 - - - Metallophos_2 k141_24564_1 1453501.JELR01000005_gene1593 4.51e-130 389.0 COG0366@1|root,COG0366@2|Bacteria,1Q8Y2@1224|Proteobacteria,1RQV0@1236|Gammaproteobacteria,464WX@72275|Alteromonadaceae 1236|Gammaproteobacteria G Alpha amylase, catalytic domain - - - - - - - - - - - - Alpha-amylase,Alpha-amylase_C,Malt_amylase_C k141_17338_1 545693.BMQ_0903 8.52e-101 300.0 COG0604@1|root,COG0604@2|Bacteria,1TQ0M@1239|Firmicutes,4HA8M@91061|Bacilli,1ZD7C@1386|Bacillus 91061|Bacilli C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - - - - - - - - - - - ADH_N,ADH_zinc_N,ADH_zinc_N_2 k141_14947_2 1042377.AFPJ01000053_gene1497 7.94e-104 320.0 COG2885@1|root,COG2885@2|Bacteria,1RCNJ@1224|Proteobacteria,1S2JT@1236|Gammaproteobacteria,46CJ1@72275|Alteromonadaceae 1236|Gammaproteobacteria M Bacterial protein of unknown function (DUF937) oprF - - ko:K03286 - - - - ko00000,ko02000 1.B.6 - - DUF937,OMP_b-brl,OmpA,OprF,TSP_3 k141_14947_3 1279017.AQYJ01000028_gene2149 2.65e-231 644.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RV50@1236|Gammaproteobacteria,464N2@72275|Alteromonadaceae 1236|Gammaproteobacteria I Belongs to the thiolase family fadA - 2.3.1.16,2.3.1.9 ko:K00626,ko:K00632 ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00087,M00088,M00095,M00113,M00373,M00374,M00375 R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095 RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N k141_37473_1 1442599.JAAN01000011_gene346 1.55e-27 107.0 COG0811@1|root,COG0811@2|Bacteria,1NCWW@1224|Proteobacteria,1RMD4@1236|Gammaproteobacteria,1X41S@135614|Xanthomonadales 135614|Xanthomonadales U TolQ protein tolQ - - ko:K03562 ko01120,map01120 - - - ko00000,ko02000 1.A.30.2.2 - - MotA_ExbB k141_22150_1 218284.CCDN010000010_gene4363 1.89e-183 511.0 COG0090@1|root,COG0090@2|Bacteria,1TP9X@1239|Firmicutes,4HAE8@91061|Bacilli,1ZCQP@1386|Bacillus 91061|Bacilli J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity rplB GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02886 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L2,Ribosomal_L2_C k141_36250_1 1453501.JELR01000006_gene14 2.95e-73 241.0 COG4223@1|root,COG4223@2|Bacteria,1N10X@1224|Proteobacteria,1RYCQ@1236|Gammaproteobacteria,46D2D@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF1631) - - - - - - - - - - - - DUF1631 k141_14079_1 218284.CCDN010000006_gene3620 1.11e-133 379.0 COG0740@1|root,COG0740@2|Bacteria,1TQ91@1239|Firmicutes,4HA8J@91061|Bacilli,1ZARS@1386|Bacillus 91061|Bacilli OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins clpP GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0006355,GO:0006508,GO:0006515,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019538,GO:0030163,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051603,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 - - - ko00000,ko00001,ko01000,ko01002 - - - CLP_protease k141_23486_1 218284.CCDN010000001_gene219 5.02e-35 130.0 COG1574@1|root,COG1574@2|Bacteria,1TQ6G@1239|Firmicutes,4H9T6@91061|Bacilli,1ZBDY@1386|Bacillus 91061|Bacilli S amidohydrolase nfdA_1 - - - - - - - - - - - Amidohydro_3 k141_7823_1 218284.CCDN010000002_gene2764 3.37e-71 223.0 COG3239@1|root,COG3239@2|Bacteria,1TP3B@1239|Firmicutes,4H9TS@91061|Bacilli,1ZAYJ@1386|Bacillus 91061|Bacilli I fatty acid desaturase des - 1.14.19.23,1.14.19.45 ko:K10255 ko02020,map02020 - - - ko00000,ko00001,ko01000,ko01004 - - - FA_desaturase k141_7823_2 1461580.CCAS010000054_gene3708 6.55e-09 55.1 COG2197@1|root,COG2197@2|Bacteria,1TVTF@1239|Firmicutes,4HAJW@91061|Bacilli,1ZGKR@1386|Bacillus 91061|Bacilli KT cheY-homologous receiver domain desR - - ko:K07693 ko02020,map02020 M00479 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg k141_11599_1 866895.HBHAL_2541 3.14e-48 158.0 COG5483@1|root,COG5483@2|Bacteria,1V4SJ@1239|Firmicutes,4HHX5@91061|Bacilli 91061|Bacilli S Protein of unknown function, DUF488 - - - - - - - - - - - - DUF488 k141_14948_1 218284.CCDN010000006_gene3590 1.07e-37 128.0 COG3278@1|root,COG3278@2|Bacteria,1VAHS@1239|Firmicutes,4HKKG@91061|Bacilli,1ZID0@1386|Bacillus 91061|Bacilli O COG3278 Cbb3-type cytochrome oxidase, subunit 1 - - - - - - - - - - - - COX1 k141_6752_1 592015.HMPREF1705_00291 3.62e-138 411.0 COG1217@1|root,COG1217@2|Bacteria,3T9TF@508458|Synergistetes 508458|Synergistetes T GTP-binding protein TypA typA - - ko:K06207 - - - - ko00000 - - - EFG_C,GTP_EFTU,GTP_EFTU_D2 k141_31438_2 218284.CCDN010000001_gene1808 1.29e-66 222.0 COG0249@1|root,COG0249@2|Bacteria,1TPRJ@1239|Firmicutes,4HA63@91061|Bacilli,1ZB93@1386|Bacillus 91061|Bacilli L that it carries out the mismatch recognition step. This protein has a weak ATPase activity mutS GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K03555 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V k141_7824_1 406124.ACPC01000018_gene2547 8.72e-22 99.0 COG0840@1|root,COG0840@2|Bacteria,1TZ8Z@1239|Firmicutes,4HBMM@91061|Bacilli,1ZDNK@1386|Bacillus 91061|Bacilli NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). mcp4 - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal k141_25864_1 218284.CCDN010000001_gene1534 2.45e-107 311.0 COG1954@1|root,COG1954@2|Bacteria,1V4IE@1239|Firmicutes,4HH9Q@91061|Bacilli,1ZCJN@1386|Bacillus 91061|Bacilli K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA glpP GO:0001072,GO:0001678,GO:0003674,GO:0005975,GO:0006066,GO:0006071,GO:0006355,GO:0008150,GO:0008152,GO:0009743,GO:0009746,GO:0009749,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0019400,GO:0019725,GO:0019751,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031554,GO:0031564,GO:0033500,GO:0034284,GO:0042221,GO:0042592,GO:0042593,GO:0043242,GO:0043244,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046677,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048878,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0055082,GO:0060255,GO:0060567,GO:0065007,GO:0065008,GO:0070887,GO:0071310,GO:0071322,GO:0071326,GO:0071331,GO:0071333,GO:0071704,GO:0080090,GO:0140110,GO:1901615,GO:1901700,GO:1901701,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - ko:K02443 - - - - ko00000,ko03000 - - - G3P_antiterm k141_24566_1 1027292.HMPREF9372_0481 0.000162 42.7 COG2318@1|root,COG2318@2|Bacteria,1V415@1239|Firmicutes,4HH2D@91061|Bacilli,26FHI@186818|Planococcaceae 91061|Bacilli S Protein of unknown function (DUF1572) - - - - - - - - - - - - DUF1572 k141_11600_1 1033734.CAET01000013_gene1777 3.07e-109 324.0 COG1914@1|root,COG1914@2|Bacteria,1V04N@1239|Firmicutes,4HBF6@91061|Bacilli,1ZF5E@1386|Bacillus 91061|Bacilli P Natural resistance-associated macrophage protein mntH_2 - - - - - - - - - - - Nramp k141_19808_1 1294265.JCM21738_2738 8.99e-24 96.7 COG3336@1|root,COG3336@2|Bacteria,1TQFK@1239|Firmicutes,4H9WN@91061|Bacilli,1ZBC8@1386|Bacillus 91061|Bacilli S cytochrome c oxidase ctaG - - ko:K02862 - - - - ko00000 - - - Caa3_CtaG k141_870_1 218284.CCDN010000002_gene2201 3.22e-67 213.0 COG4362@1|root,COG4362@2|Bacteria,1TRDM@1239|Firmicutes,4HAR0@91061|Bacilli,1ZB33@1386|Bacillus 91061|Bacilli C Belongs to the NOS family. Bacterial NOS oxygenase subfamily nos GO:0001505,GO:0003674,GO:0003824,GO:0004497,GO:0004517,GO:0006807,GO:0006809,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016705,GO:0016709,GO:0017144,GO:0034641,GO:0042133,GO:0042136,GO:0044237,GO:0044249,GO:0044271,GO:0046209,GO:0055114,GO:0065007,GO:0065008,GO:0072593,GO:1903409,GO:2001057 1.14.14.47 ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 - R11711,R11712,R11713 RC00177,RC00330,RC01044 ko00000,ko00001,ko01000 - - - NO_synthase k141_870_2 218284.CCDN010000002_gene2200 2.56e-105 306.0 COG1670@1|root,COG1670@2|Bacteria,1UHTR@1239|Firmicutes,4IS9D@91061|Bacilli,1ZS3J@1386|Bacillus 91061|Bacilli J Acetyltransferase (GNAT) family - - - - - - - - - - - - Acetyltransf_1 k141_870_3 218284.CCDN010000002_gene2199 1.75e-34 126.0 COG3380@1|root,COG3380@2|Bacteria,1UZWW@1239|Firmicutes,4HFJT@91061|Bacilli,1ZG2V@1386|Bacillus 91061|Bacilli S Flavin containing amine oxidoreductase - - - ko:K06955 - - - - ko00000 - - - Amino_oxidase,NAD_binding_8 k141_23488_1 574966.KB898649_gene252 1.11e-81 266.0 COG1080@1|root,COG4668@1|root,COG1080@2|Bacteria,COG4668@2|Bacteria,1MUT8@1224|Proteobacteria,1RN6R@1236|Gammaproteobacteria,1XNNQ@135619|Oceanospirillales 135619|Oceanospirillales G Belongs to the PEP-utilizing enzyme family - - 2.7.1.202,2.7.3.9 ko:K02768,ko:K08483,ko:K11183 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1,8.A.7 - - PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C,PTS-HPr,PTS_EIIA_2 k141_14949_1 218284.CCDN010000002_gene2251 9.12e-119 354.0 COG0069@1|root,COG0069@2|Bacteria,1TSHA@1239|Firmicutes,4HA97@91061|Bacilli,1ZCQH@1386|Bacillus 91061|Bacilli E Belongs to the glutamate synthase family yerD GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.7.1 ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 - R00021,R10086 RC00006,RC00010 ko00000,ko00001,ko01000 - - - Glu_synthase k141_22152_1 218284.CCDN010000001_gene606 2.62e-79 252.0 COG1388@1|root,COG1388@2|Bacteria,1U052@1239|Firmicutes,4HF2C@91061|Bacilli,1ZB2H@1386|Bacillus 91061|Bacilli M stage VI sporulation protein D spoVID GO:0003674,GO:0005488,GO:0005515,GO:0019899,GO:0051117 - ko:K06417 - - - - ko00000 - - - LysM k141_30290_1 1453501.JELR01000002_gene682 9.54e-40 149.0 COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,1RQR7@1236|Gammaproteobacteria,4668G@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria ycbB GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0006508,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0008236,GO:0008238,GO:0009273,GO:0009987,GO:0016740,GO:0016746,GO:0016755,GO:0016787,GO:0016807,GO:0017171,GO:0019538,GO:0033554,GO:0042546,GO:0043164,GO:0043170,GO:0044036,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0050896,GO:0051716,GO:0070004,GO:0070008,GO:0070011,GO:0071554,GO:0071704,GO:0071840,GO:0071972,GO:0140096,GO:1901564 - ko:K21470 - - - - ko00000,ko01002,ko01011 - - - PG_binding_1,YkuD k141_7825_2 218284.CCDN010000001_gene714 5.55e-48 160.0 COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,4HD4R@91061|Bacilli,1ZANW@1386|Bacillus 91061|Bacilli E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) aroE GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000 - - - Shikimate_DH,Shikimate_dh_N k141_6753_1 714961.BFZC1_12508 5.59e-62 207.0 COG0770@1|root,COG0770@2|Bacteria,1UPUZ@1239|Firmicutes,4HTD6@91061|Bacilli,3IXF0@400634|Lysinibacillus 91061|Bacilli M Mur ligase family, glutamate ligase domain - - 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 - R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase_C,Mur_ligase_M k141_20869_1 218284.CCDN010000005_gene3225 4.38e-197 553.0 COG2356@1|root,COG4085@1|root,COG2356@2|Bacteria,COG4085@2|Bacteria,1U9GI@1239|Firmicutes,4IJKB@91061|Bacilli,1ZAYK@1386|Bacillus 91061|Bacilli L Ribonuclease bsn GO:0005575,GO:0005576 - - - - - - - - - - Endonuclease_1 k141_14081_1 1453501.JELR01000002_gene1012 1.52e-115 340.0 COG0604@1|root,COG0604@2|Bacteria,1QY04@1224|Proteobacteria,1RSP0@1236|Gammaproteobacteria,46BBM@72275|Alteromonadaceae 1236|Gammaproteobacteria C Zinc-binding dehydrogenase - - 1.1.1.1 ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N,ADH_zinc_N_2,KR,PP-binding,PS-DH k141_11601_1 1234664.AMRO01000079_gene590 4.02e-100 312.0 COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,4HAAG@91061|Bacilli,1WEKS@129337|Geobacillus 91061|Bacilli G Fibronectin type III-like domain bglX - 3.2.1.21,3.2.1.52 ko:K01207,ko:K05349 ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501 M00628 R00022,R00026,R02558,R02887,R02985,R03527,R04949,R04998,R05963,R07809,R07810,R10035,R10039,R10040,R10831 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko00002,ko01000 - GH3 - Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C k141_36251_1 69042.WH5701_04995 1.56e-134 406.0 COG3119@1|root,COG3119@2|Bacteria,1G3QV@1117|Cyanobacteria,1GZW2@1129|Synechococcus 1117|Cyanobacteria P COG3119 Arylsulfatase A and related enzymes - - 3.1.6.1 ko:K01130 ko00140,ko00600,map00140,map00600 - R03980,R04856 RC00128,RC00231 ko00000,ko00001,ko01000 - - - Sulfatase k141_25865_1 1307436.PBF_07701 1.8e-101 302.0 COG0130@1|root,COG0130@2|Bacteria,1TP9Y@1239|Firmicutes,4HA9X@91061|Bacilli,1ZBKE@1386|Bacillus 91061|Bacilli J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs truB GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 ko:K03177,ko:K03483 - - - - ko00000,ko01000,ko03000,ko03016 - - iSB619.SA_RS06305 TruB-C_2,TruB_C_2,TruB_N k141_25865_2 218284.CCDN010000001_gene1886 7.02e-07 48.5 COG0858@1|root,COG0858@2|Bacteria,1VA0P@1239|Firmicutes,4HII1@91061|Bacilli,1ZGB3@1386|Bacillus 91061|Bacilli J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA rbfA - - ko:K02834 - - - - ko00000,ko03009 - - - RBFA k141_16181_1 1453501.JELR01000005_gene1697 1.33e-16 83.6 COG4247@1|root,COG4247@2|Bacteria,1MVTA@1224|Proteobacteria,1RQXH@1236|Gammaproteobacteria,46571@72275|Alteromonadaceae 1236|Gammaproteobacteria I Phytase phy - 3.1.3.8 ko:K01083 ko00562,map00562 - R03371 RC00078 ko00000,ko00001,ko01000 - - - Phytase k141_3036_1 1177154.Y5S_01705 1.2e-59 207.0 COG2885@1|root,COG2885@2|Bacteria,1QW22@1224|Proteobacteria,1T4AK@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Ompa motb domain protein - - - - - - - - - - - - DUF11,OmpA k141_35597_4 1042377.AFPJ01000038_gene1121 2.29e-31 124.0 COG4206@1|root,COG4206@2|Bacteria,1MUZG@1224|Proteobacteria,1RP7I@1236|Gammaproteobacteria,463Z2@72275|Alteromonadaceae 1236|Gammaproteobacteria H COG1629 Outer membrane receptor proteins, mostly Fe transport - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - CarboxypepD_reg,Plug,TonB_dep_Rec k141_13009_4 391615.ABSJ01000027_gene215 0.0 1811.0 COG0610@1|root,COG0610@2|Bacteria,1MU96@1224|Proteobacteria,1RP2Q@1236|Gammaproteobacteria,1J550@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria V Subunit R is required for both nuclease and ATPase activities, but not for modification - - 3.1.21.3 ko:K01153 - - - - ko00000,ko01000,ko02048 - - - HSDR_N,ResIII k141_13009_5 1045855.DSC_11735 1.25e-42 160.0 COG0732@1|root,COG0732@2|Bacteria,1PEA7@1224|Proteobacteria,1T6ER@1236|Gammaproteobacteria,1XAQR@135614|Xanthomonadales 135614|Xanthomonadales L Type I restriction modification DNA specificity domain - - 3.1.21.3 ko:K01154 - - - - ko00000,ko01000,ko02048 - - - Methylase_S k141_13009_6 754436.JCM19237_1741 0.0 909.0 COG0286@1|root,COG0286@2|Bacteria,1MW3A@1224|Proteobacteria,1RMRA@1236|Gammaproteobacteria,1XVW9@135623|Vibrionales 135623|Vibrionales V COG0286 Type I restriction-modification system methyltransferase subunit - - 2.1.1.72 ko:K03427 - - - - ko00000,ko01000,ko02048 - - - HsdM_N,N6_Mtase k141_13009_7 391615.ABSJ01000027_gene219 0.0 904.0 COG0286@1|root,COG0286@2|Bacteria,1MW3A@1224|Proteobacteria,1RMRA@1236|Gammaproteobacteria,1J5H0@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria V Type I restriction-modification system - - 2.1.1.72 ko:K03427 - - - - ko00000,ko01000,ko02048 - - - HsdM_N,N6_Mtase k141_13009_8 754436.JCM19237_1738 6.18e-33 114.0 COG3311@1|root,COG3311@2|Bacteria,1N72I@1224|Proteobacteria,1SDJ2@1236|Gammaproteobacteria,1XZBE@135623|Vibrionales 135623|Vibrionales K Helix-turn-helix domain - - - - - - - - - - - - HTH_17 k141_13009_9 398579.Spea_1269 1.25e-294 834.0 COG0553@1|root,COG0553@2|Bacteria,1MX26@1224|Proteobacteria,1RZZU@1236|Gammaproteobacteria 1236|Gammaproteobacteria L DEAD-like helicases superfamily - - - - - - - - - - - - Helicase_C k141_24807_1 1453501.JELR01000002_gene1157 2.99e-165 469.0 COG0583@1|root,COG0583@2|Bacteria,1MZTA@1224|Proteobacteria,1RN7R@1236|Gammaproteobacteria,464C1@72275|Alteromonadaceae 1236|Gammaproteobacteria K transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_24807_2 1267600.JFGT01000002_gene931 5.62e-39 135.0 COG2259@1|root,COG2259@2|Bacteria,1MZVP@1224|Proteobacteria,1S8UI@1236|Gammaproteobacteria,3W0II@53335|Pantoea 1236|Gammaproteobacteria S membrane yqjF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K15977 - - - - ko00000 - - - DoxX k141_26140_1 218284.CCDN010000007_gene3960 3.62e-142 431.0 COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,1TQAD@1239|Firmicutes,4HCMS@91061|Bacilli,1ZBF6@1386|Bacillus 91061|Bacilli EI Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly icmF GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046906,GO:0046983,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 ko:K11942 - - - - ko00000,ko01000 - - - ArgK,B12-binding,MM_CoA_mutase k141_37706_2 523791.Kkor_0405 1.46e-88 268.0 COG3739@1|root,COG3739@2|Bacteria,1PMEC@1224|Proteobacteria,1S0M3@1236|Gammaproteobacteria,1XNIV@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF817) - - - - - - - - - - - - DUF817 k141_29515_1 1274524.BSONL12_15819 1.97e-98 292.0 COG1647@1|root,COG1647@2|Bacteria,1TQ7X@1239|Firmicutes,4HBE6@91061|Bacilli,1ZAVD@1386|Bacillus 91061|Bacilli S Carboxylesterase est GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0008150,GO:0008152,GO:0016020,GO:0016298,GO:0016787,GO:0016788,GO:0044238,GO:0071704 3.1.1.1 ko:K03928 - - - - ko00000,ko01000 - - - Hydrolase_4 k141_28129_2 218284.CCDN010000001_gene970 1.08e-74 228.0 COG1253@1|root,COG1253@2|Bacteria,1VBH3@1239|Firmicutes,4HFR4@91061|Bacilli,1ZEWH@1386|Bacillus 91061|Bacilli S flavin adenine dinucleotide binding - - - - - - - - - - - - - k141_10519_1 218284.CCDN010000002_gene2056 3.85e-120 360.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,1ZBIW@1386|Bacillus 91061|Bacilli V COG1132 ABC-type multidrug transport system, ATPase and permease components yfiC3 - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran k141_10519_2 1122918.KB907245_gene5185 4.44e-08 53.9 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4H9SC@91061|Bacilli,26QMC@186822|Paenibacillaceae 91061|Bacilli V ABC transporter, ATP-binding protein yfiB3 - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran k141_29516_1 1294265.JCM21738_603 3.75e-139 395.0 COG0379@1|root,COG0379@2|Bacteria,1TP6R@1239|Firmicutes,4H9QG@91061|Bacilli,1ZAR3@1386|Bacillus 91061|Bacilli H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate nadA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 ko:K03517 ko00760,ko01100,map00760,map01100 M00115 R04292 RC01119 ko00000,ko00001,ko00002,ko01000 - - - NadA k141_35599_1 1294265.JCM21738_3042 5.02e-119 342.0 COG0344@1|root,COG0344@2|Bacteria,1VA3J@1239|Firmicutes,4HC55@91061|Bacilli,1ZFP9@1386|Bacillus 91061|Bacilli I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP plsY - 2.3.1.15 ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - G3P_acyltransf k141_33018_1 1116375.VEJY3_17796 8.43e-142 413.0 COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,1RMPS@1236|Gammaproteobacteria,1XTWB@135623|Vibrionales 135623|Vibrionales H Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration nnrD - 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 - - - - ko00000,ko01000 - - - Carb_kinase,YjeF_N k141_33018_2 1219076.N646_3954 2.97e-244 671.0 COG0516@1|root,COG0516@2|Bacteria,1MUJM@1224|Proteobacteria,1RPZY@1236|Gammaproteobacteria,1XUGZ@135623|Vibrionales 135623|Vibrionales F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides guaC GO:0003674,GO:0003824,GO:0003920,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0015949,GO:0016491,GO:0016651,GO:0016657,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:1901360 1.7.1.7 ko:K00364 ko00230,map00230 - R01134 RC00457 ko00000,ko00001,ko01000 - - - IMPDH k141_33018_3 223926.28808607 1.17e-159 458.0 28IWB@1|root,2Z8UK@2|Bacteria,1P3IX@1224|Proteobacteria,1RRBU@1236|Gammaproteobacteria,1XSD8@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF3360) - - - - - - - - - - - - DUF3360 k141_16439_1 867903.ThesuDRAFT_01894 1.81e-66 219.0 COG2987@1|root,COG2987@2|Bacteria,1TPZ9@1239|Firmicutes,247YS@186801|Clostridia,3WCXW@538999|Clostridiales incertae sedis 186801|Clostridia E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate hutU - 4.2.1.49 ko:K01712 ko00340,ko01100,map00340,map01100 M00045 R02914 RC00804 ko00000,ko00001,ko00002,ko01000 - - - Urocanase,Urocanase_C,Urocanase_N k141_13012_1 935836.JAEL01000025_gene2339 5.95e-44 144.0 COG3224@1|root,COG3224@2|Bacteria,1V83H@1239|Firmicutes,4HJC6@91061|Bacilli,1ZHQD@1386|Bacillus 91061|Bacilli S EthD domain ethD - - - - - - - - - - - EthD k141_5879_1 998674.ATTE01000001_gene494 1.04e-32 119.0 COG0259@1|root,COG0259@2|Bacteria,1NZUU@1224|Proteobacteria,1RMQ2@1236|Gammaproteobacteria,460KC@72273|Thiotrichales 72273|Thiotrichales H Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) pdxH - 1.4.3.5 ko:K00275 ko00750,ko01100,ko01120,map00750,map01100,map01120 M00124 R00277,R00278,R01710,R01711 RC00048,RC00116 ko00000,ko00001,ko00002,ko01000 - - - PNP_phzG_C,Putative_PNPOx k141_5879_2 1283300.ATXB01000001_gene715 2.54e-35 122.0 COG0662@1|root,COG0662@2|Bacteria,1N7Q4@1224|Proteobacteria,1SEVR@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Cupin domain - - - - - - - - - - - - Cupin_2 k141_5879_3 1453501.JELR01000001_gene1887 1.18e-112 338.0 COG0443@1|root,COG0443@2|Bacteria,1MUR1@1224|Proteobacteria,1RR7P@1236|Gammaproteobacteria,469ME@72275|Alteromonadaceae 1236|Gammaproteobacteria O MreB/Mbl protein hscC GO:0003674,GO:0003824,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111 - ko:K04045 - - - - ko00000,ko03110 1.A.33 - iSFV_1184.SFV_0676 HSP70,MreB_Mbl k141_29518_1 42565.FP66_14775 1.04e-100 313.0 COG0668@1|root,COG0668@2|Bacteria,1MY0I@1224|Proteobacteria,1RQKY@1236|Gammaproteobacteria,1XJP8@135619|Oceanospirillales 135619|Oceanospirillales M COG0668 Small-conductance mechanosensitive channel - - - ko:K22044 - - - - ko00000,ko02000 1.A.23.3 - - MS_channel k141_10520_1 935836.JAEL01000061_gene3713 2.12e-119 342.0 COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,4HAC9@91061|Bacilli,1ZCEB@1386|Bacillus 91061|Bacilli J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit rpsD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - ko:K02986 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S4,S4 k141_28130_2 626887.J057_15245 3.01e-67 208.0 2BY4C@1|root,32XUX@2|Bacteria,1N0C0@1224|Proteobacteria,1SAJV@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_4515_1 1279017.AQYJ01000028_gene2448 2.67e-98 293.0 COG0664@1|root,COG0664@2|Bacteria,1RE4X@1224|Proteobacteria,1S6Z7@1236|Gammaproteobacteria,46CPH@72275|Alteromonadaceae 1236|Gammaproteobacteria K Crp-like helix-turn-helix domain - - - ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 - - - ko00000,ko00001,ko03000 - - - HTH_Crp_2,cNMP_binding k141_4515_2 1279017.AQYJ01000028_gene2449 5.74e-150 425.0 COG0235@1|root,COG0235@2|Bacteria,1MWP9@1224|Proteobacteria,1RQNI@1236|Gammaproteobacteria,4643V@72275|Alteromonadaceae 1236|Gammaproteobacteria G Class II aldolase - - - - - - - - - - - - Aldolase_II k141_4515_4 316273.XCV1381 1.36e-101 314.0 COG2265@1|root,COG2265@2|Bacteria,1MV3A@1224|Proteobacteria,1RN1D@1236|Gammaproteobacteria,1X4IP@135614|Xanthomonadales 135614|Xanthomonadales J Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA rlmD - 2.1.1.190 ko:K03215 - - - - ko00000,ko01000,ko03009 - - - TRAM,tRNA_U5-meth_tr k141_26143_1 391589.RGAI101_2037 1.86e-27 108.0 COG3496@1|root,COG3496@2|Bacteria,1RC56@1224|Proteobacteria,2TUX0@28211|Alphaproteobacteria,2P236@2433|Roseobacter 28211|Alphaproteobacteria S Protein of unknown function (DUF1365) - - - ko:K09701 - - - - ko00000 - - - DUF1365 k141_26143_2 69279.BG36_18680 1.22e-18 85.1 COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,2TR8K@28211|Alphaproteobacteria,43J8X@69277|Phyllobacteriaceae 28211|Alphaproteobacteria M Cyclopropane-fatty-acyl-phospholipid synthase cfaS - 2.1.1.79 ko:K00574 - - - - ko00000,ko01000 - - - CMAS k141_35601_1 218284.CCDN010000005_gene3247 2.02e-103 315.0 COG0366@1|root,COG0366@2|Bacteria,1TNZ0@1239|Firmicutes,4HB67@91061|Bacilli,1ZAZP@1386|Bacillus 91061|Bacilli G Alpha amylase, N-terminal ig-like domain nplT - 3.2.1.133,3.2.1.135,3.2.1.54 ko:K01208 ko00500,ko01100,map00500,map01100 - R02112,R03122,R11262 - ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,Alpha-amylase_N,Malt_amylase_C k141_17526_4 749413.E5DV84_9VIRU 1.31e-53 173.0 4QAKE@10239|Viruses 10239|Viruses S endonuclease activity - - - - - - - - - - - - - k141_17526_6 1444310.JANV01000162_gene1198 9.05e-42 149.0 2DC6Z@1|root,2ZD43@2|Bacteria 2|Bacteria S HNH endonuclease - - - - - - - - - - - - HNH_3 k141_7955_60 1395587.P364_0119245 1.73e-06 57.4 COG0639@1|root,COG0639@2|Bacteria,1V1HN@1239|Firmicutes,4HG6T@91061|Bacilli,26UCQ@186822|Paenibacillaceae 91061|Bacilli T Calcineurin-like phosphoesterase pphA - 3.1.3.16 ko:K07313 - - - - ko00000,ko01000 - - - Metallophos k141_7955_62 445685.E3SKI9_9CAUD 4.22e-90 278.0 4QAR1@10239|Viruses,4QUNA@35237|dsDNA viruses no RNA stage,4QPJE@28883|Caudovirales,4QI9Y@10662|Myoviridae 10662|Myoviridae S ATPase family associated with various cellular activities (AAA) - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039686,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k141_7955_63 754038.G8EYB8_9CAUD 2.53e-33 120.0 4QBC7@10239|Viruses,4QUQW@35237|dsDNA viruses no RNA stage,4QPGT@28883|Caudovirales,4QIH8@10662|Myoviridae 10662|Myoviridae S Pfam:Phage_clamp_A - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039686,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k141_7955_64 445686.E3SL93_9CAUD 2.58e-35 126.0 4QBKQ@10239|Viruses,4QVKF@35237|dsDNA viruses no RNA stage,4QQM7@28883|Caudovirales,4QIAS@10662|Myoviridae 10662|Myoviridae S Bacteriophage translational regulator - - - - - - - - - - - - - k141_7955_68 1204516.I6XH85_9CAUD 3.54e-19 85.9 4QBNM@10239|Viruses,4QVXP@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales,4QII1@10662|Myoviridae 10662|Myoviridae S N-methyltransferase activity - - - - - - - - - - - - - k141_7955_74 444861.E3SPN9_9CAUD 1.41e-235 690.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales 28883|Caudovirales S DNA polymerase family B - GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016032,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019058,GO:0019079,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0039686,GO:0039693,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044403,GO:0044419,GO:0046483,GO:0051704,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 - - - - - - - - - - - k141_7955_75 1150989.H6WXG4_9CAUD 5.06e-30 119.0 4QG24@10239|Viruses,4QV8E@35237|dsDNA viruses no RNA stage,4QSGP@28883|Caudovirales,4QM3Q@10699|Siphoviridae 10699|Siphoviridae S (deoxy)nucleoside-phosphate kinase activity - GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0044237,GO:0047507 - - - - - - - - - - - k141_7955_76 1223410.KN050846_gene1429 1.98e-113 335.0 COG0207@1|root,COG0207@2|Bacteria,4NEC2@976|Bacteroidetes,1HX2F@117743|Flavobacteriia 976|Bacteroidetes F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis thyA - 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 - - - Thymidylat_synt k141_7955_78 227470.Q76Z75_9CAUD 3.58e-131 388.0 4QASV@10239|Viruses,4QWD9@35237|dsDNA viruses no RNA stage,4QQ4N@28883|Caudovirales,4QIBN@10662|Myoviridae 10662|Myoviridae S recA bacterial DNA recombination protein - - - - - - - - - - - - - k141_7955_79 1493511.A0A0E3FLK1_9CAUD 3.12e-131 394.0 4QAWG@10239|Viruses,4QPII@28883|Caudovirales,4QI76@10662|Myoviridae 10662|Myoviridae S DNA helicase activity - - - - - - - - - - - - - k141_7955_92 238854.Q5GQI8_BPSYP 1.18e-65 217.0 4QCWD@10239|Viruses,4QUQN@35237|dsDNA viruses no RNA stage,4QUCZ@28883|Caudovirales 28883|Caudovirales S DNA primase activity - - - - - - - - - - - - - k141_7955_96 880526.KE386488_gene871 3.81e-23 96.7 COG0262@1|root,COG0262@2|Bacteria,4NQ2Y@976|Bacteroidetes,2FT42@200643|Bacteroidia,22UHP@171550|Rikenellaceae 976|Bacteroidetes H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis folA - 1.5.1.3 ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 M00126,M00840 R00936,R00937,R00939,R00940,R02235,R02236,R11765 RC00109,RC00110,RC00158 ko00000,ko00001,ko00002,ko01000 - - - 2TM,DHFR_1 k141_7955_97 1111732.AZOD01000009_gene1166 3.47e-238 688.0 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,1RMPV@1236|Gammaproteobacteria,1X48F@135614|Xanthomonadales 135614|Xanthomonadales F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides - - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN k141_7955_98 10726.Q6QGJ3_BPT5 6.6e-77 248.0 4QC2G@10239|Viruses,4QV3V@35237|dsDNA viruses no RNA stage,4QPRR@28883|Caudovirales,4QM50@10699|Siphoviridae 10699|Siphoviridae S Ribonucleotide reductase, small chain - - - - - - - - - - - - - k141_7955_99 1357714.A0A067XQR5_9CAUD 4.87e-20 82.8 4QAQV@10239|Viruses,4QUPK@35237|dsDNA viruses no RNA stage,4QPCB@28883|Caudovirales,4QHY7@10662|Myoviridae 10662|Myoviridae S protein disulfide oxidoreductase activity - - - - - - - - - - - - - k141_7955_100 1357714.A0A067XQT2_9CAUD 5.75e-29 112.0 4QCUC@10239|Viruses,4QY13@35237|dsDNA viruses no RNA stage,4QQ7E@28883|Caudovirales,4QIRS@10662|Myoviridae 10662|Myoviridae S endodeoxyribonuclease activity - - - - - - - - - - - - - k141_7955_101 1121094.KB894643_gene1744 6.43e-30 115.0 COG2131@1|root,COG2131@2|Bacteria,4NM48@976|Bacteroidetes,2FRZ1@200643|Bacteroidia,4AQJS@815|Bacteroidaceae 976|Bacteroidetes F Cytidine and deoxycytidylate deaminase zinc-binding region comEB - 3.5.4.12 ko:K01493 ko00240,ko01100,map00240,map01100 M00429 R01663 RC00074 ko00000,ko00001,ko00002,ko01000,ko02044 - - - dCMP_cyt_deam_1 k141_7955_104 1429794.A0A0A0PZM6_9CAUD 2.07e-28 114.0 4QEWD@10239|Viruses,4QXJF@35237|dsDNA viruses no RNA stage,4QUH5@28883|Caudovirales,4QKJD@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k141_7955_111 1141136.K4F786_9CAUD 5.19e-63 218.0 4QAUT@10239|Viruses,4QVIM@35237|dsDNA viruses no RNA stage,4QQ7X@28883|Caudovirales,4QIGV@10662|Myoviridae 10662|Myoviridae S DNA ligase (ATP) activity - - - - - - - - - - - - - k141_1204_1 1219077.VAZ01S_079_00160 4.68e-73 219.0 COG0335@1|root,COG0335@2|Bacteria,1RH3A@1224|Proteobacteria,1S5XX@1236|Gammaproteobacteria,1XXCD@135623|Vibrionales 135623|Vibrionales J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site rplS GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02884 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L19 k141_1204_2 1116375.VEJY3_13065 5.05e-182 506.0 COG0336@1|root,COG0336@2|Bacteria,1MUN1@1224|Proteobacteria,1RMWC@1236|Gammaproteobacteria,1XSG2@135623|Vibrionales 135623|Vibrionales J Belongs to the RNA methyltransferase TrmD family trmD GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 ko:K00554 - - R00597 RC00003,RC00334 ko00000,ko01000,ko03016 - - - tRNA_m1G_MT k141_1204_3 1219076.N646_1625 1.76e-131 372.0 COG0806@1|root,COG0806@2|Bacteria,1MWQR@1224|Proteobacteria,1RNJ2@1236|Gammaproteobacteria,1XSFG@135623|Vibrionales 135623|Vibrionales J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes rimM GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 - ko:K02860 - - - - ko00000,ko03009 - - - PRC,RimM k141_1204_4 1136163.M565_ctg1P0090 8.4e-53 166.0 COG0228@1|root,COG0228@2|Bacteria,1MZCT@1224|Proteobacteria,1S8RT@1236|Gammaproteobacteria,1XXZF@135623|Vibrionales 135623|Vibrionales J Belongs to the bacterial ribosomal protein bS16 family rpsP GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02959 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S16 k141_8390_1 1385511.N783_18735 1.91e-63 204.0 COG1131@1|root,COG1131@2|Bacteria,1TPMQ@1239|Firmicutes,4IPMF@91061|Bacilli,2Y9NY@289201|Pontibacillus 91061|Bacilli V Daunorubicin ABC transporter ATPase - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 k141_21444_1 675814.VIC_002511 5.9e-101 298.0 COG1922@1|root,COG1922@2|Bacteria,1N1HD@1224|Proteobacteria,1RP6P@1236|Gammaproteobacteria,1XST5@135623|Vibrionales 135623|Vibrionales M Belongs to the glycosyltransferase 26 family - - 2.4.1.187 ko:K05946 ko05111,map05111 - - - ko00000,ko00001,ko01000,ko01003 - GT26 - Glyco_tran_WecB k141_35719_1 218284.CCDN010000002_gene2646 5.08e-133 396.0 COG1762@1|root,COG3711@1|root,COG1762@2|Bacteria,COG3711@2|Bacteria,1TQT1@1239|Firmicutes,4H9N4@91061|Bacilli,1ZBCM@1386|Bacillus 91061|Bacilli GKT COG3711 Transcriptional antiterminator - - 2.7.1.194 ko:K02821 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 M00283,M00550 R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.7.1 - - HTH_11,Mga,PRD,PTS_EIIA_2,PTS_IIB k141_36898_7 1219076.N646_2983 0.0 906.0 COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1MY1V@1224|Proteobacteria,1RMYZ@1236|Gammaproteobacteria,1XTN9@135623|Vibrionales 135623|Vibrionales G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific nagE - 2.7.1.193 ko:K02803,ko:K02804 ko00520,ko02060,map00520,map02060 M00267 R05199 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.15,4.A.1.1.2,4.A.1.1.5,4.A.1.1.7 - - PTS_EIIB,PTS_EIIC k141_36898_8 1116375.VEJY3_03770 4.01e-260 714.0 COG1820@1|root,COG1820@2|Bacteria,1MW8Y@1224|Proteobacteria,1RMRV@1236|Gammaproteobacteria,1XT70@135623|Vibrionales 135623|Vibrionales G Belongs to the metallo-dependent hydrolases superfamily. NagA family nagA GO:0003674,GO:0003824,GO:0006040,GO:0006044,GO:0006046,GO:0008150,GO:0008152,GO:0008448,GO:0009056,GO:0009987,GO:0016043,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0022607,GO:0043933,GO:0044085,GO:0046348,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901575 3.5.1.25 ko:K01443 ko00520,ko01130,map00520,map01130 - R02059 RC00166,RC00300 ko00000,ko00001,ko01000 - - - Amidohydro_1 k141_36898_9 1116375.VEJY3_03765 5.46e-278 761.0 COG1846@1|root,COG1940@1|root,COG1846@2|Bacteria,COG1940@2|Bacteria,1NFM0@1224|Proteobacteria,1RNEA@1236|Gammaproteobacteria,1XT2N@135623|Vibrionales 135623|Vibrionales K COG1940 Transcriptional regulator sugar kinase nagC - - ko:K02565 - - - - ko00000,ko03000 - - - MarR,ROK k141_36898_10 1116375.VEJY3_03760 0.0 896.0 COG1226@1|root,COG4651@1|root,COG1226@2|Bacteria,COG4651@2|Bacteria,1MV34@1224|Proteobacteria,1RNH4@1236|Gammaproteobacteria,1XV3J@135623|Vibrionales 135623|Vibrionales P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family - - - - - - - - - - - - Na_H_Exchanger,TrkA_N k141_83_2 1279017.AQYJ01000024_gene916 9.66e-18 79.7 COG1057@1|root,COG1057@2|Bacteria,1RD0J@1224|Proteobacteria,1RP00@1236|Gammaproteobacteria,46745@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) nadD GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034355,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043094,GO:0043173,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18,3.5.4.4 ko:K00969,ko:K01488 ko00230,ko00760,ko01100,ko05340,map00230,map00760,map01100,map05340 M00115 R00137,R01560,R02556,R03005 RC00002,RC00477 ko00000,ko00001,ko00002,ko01000 - - iECUMN_1333.ECUMN_0733,iJN746.PP_4810,iPC815.YPO2607,iSbBS512_1146.SbBS512_E0612 CTP_transf_like k141_25008_1 218284.CCDN010000005_gene3333 2.22e-83 255.0 COG0760@1|root,COG0760@2|Bacteria,1V831@1239|Firmicutes,4HIND@91061|Bacilli,1ZCCR@1386|Bacillus 91061|Bacilli O COG0760 Parvulin-like peptidyl-prolyl isomerase - - - - - - - - - - - - SurA_N_3 k141_8411_1 218284.CCDN010000005_gene3407 7.37e-162 456.0 COG0320@1|root,COG0320@2|Bacteria,1TQM4@1239|Firmicutes,4H9SW@91061|Bacilli,1ZB5D@1386|Bacillus 91061|Bacilli H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives lipA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 ko:K03644 ko00785,ko01100,map00785,map01100 - R07767,R07768 RC01978 ko00000,ko00001,ko01000 - - - LIAS_N,Radical_SAM k141_8411_2 218284.CCDN010000005_gene3406 1.73e-18 84.0 COG0739@1|root,COG0739@2|Bacteria,1TQMQ@1239|Firmicutes,4HC7V@91061|Bacilli,1ZAQT@1386|Bacillus 91061|Bacilli M Peptidase, M23 lytH - - ko:K21472 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_M23 k141_2458_1 1116375.VEJY3_14870 1.92e-312 853.0 COG1249@1|root,COG1249@2|Bacteria,1MVVE@1224|Proteobacteria,1RMJT@1236|Gammaproteobacteria,1XSSW@135623|Vibrionales 135623|Vibrionales C Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation sthA GO:0003674,GO:0003824,GO:0003957,GO:0005215,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0008746,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0016491,GO:0016651,GO:0016652,GO:0022857,GO:0022890,GO:0034220,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.6.1.1 ko:K00322 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - Pyr_redox_2,Pyr_redox_dim k141_2458_2 674977.VMC_40840 7.63e-93 283.0 COG0534@1|root,COG0534@2|Bacteria,1MV6B@1224|Proteobacteria,1RPGF@1236|Gammaproteobacteria,1XSWY@135623|Vibrionales 135623|Vibrionales V Na driven multidrug efflux pump dinF - - ko:K03327 - - - - ko00000,ko02000 2.A.66.1 - - MatE k141_1222_1 1453501.JELR01000001_gene2823 2.38e-102 303.0 COG0583@1|root,COG0583@2|Bacteria,1NYPZ@1224|Proteobacteria,1RXYS@1236|Gammaproteobacteria,46558@72275|Alteromonadaceae 1236|Gammaproteobacteria K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_22667_1 342610.Patl_0414 1.18e-05 49.3 COG4773@1|root,COG4773@2|Bacteria,1Q323@1224|Proteobacteria,1RSQ6@1236|Gammaproteobacteria,2Q1TM@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec k141_16682_1 218284.CCDN010000001_gene1671 1.82e-92 273.0 COG4807@1|root,COG4807@2|Bacteria,1V4DA@1239|Firmicutes,4HH2A@91061|Bacilli,1ZFS1@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF1456) - - - - - - - - - - - - DUF1456 k141_16682_2 218284.CCDN010000001_gene1670 1.65e-17 79.0 COG1451@1|root,COG1451@2|Bacteria,1V6WP@1239|Firmicutes,4IR2I@91061|Bacilli,1ZRQZ@1386|Bacillus 91061|Bacilli S WLM domain - - - ko:K07043 - - - - ko00000 - - - DUF45 k141_7172_2 1347087.CBYO010000022_gene3627 4.79e-51 163.0 COG0537@1|root,COG0537@2|Bacteria,1V9QX@1239|Firmicutes,4HJD9@91061|Bacilli 91061|Bacilli FG HIT family hydrolase - - - ko:K02503 - - - - ko00000,ko04147 - - - HIT k141_4833_1 218284.CCDN010000002_gene2590 5.4e-121 353.0 COG0760@1|root,COG0760@2|Bacteria,1V2D1@1239|Firmicutes,4HFU5@91061|Bacilli,1ZRKY@1386|Bacillus 91061|Bacilli O Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins prsA - 5.2.1.8 ko:K07533 - - - - ko00000,ko01000,ko03110 - - - Rotamase_2,Rotamase_3,SurA_N_3 k141_28605_1 1196031.ALEG01000034_gene5347 2.8e-63 195.0 COG0346@1|root,COG0346@2|Bacteria,1V9E0@1239|Firmicutes,4HX0J@91061|Bacilli,1ZHMS@1386|Bacillus 91061|Bacilli E Glyoxalase-like domain - - 4.4.1.5 ko:K01759 ko00620,map00620 - R02530 RC00004,RC00740 ko00000,ko00001,ko01000 - - - Glyoxalase_2 k141_29768_1 1453501.JELR01000002_gene1395 1.67e-197 566.0 COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,COG3706@2|Bacteria,1PJCA@1224|Proteobacteria,1RS4H@1236|Gammaproteobacteria,4663N@72275|Alteromonadaceae 1236|Gammaproteobacteria T Putative diguanylate phosphodiesterase - - - ko:K21025 ko02025,map02025 - - - ko00000,ko00001 - - - EAL,GGDEF,PAS,PAS_8,PAS_9,Response_reg k141_11937_1 1453501.JELR01000002_gene833 2.82e-84 269.0 COG5434@1|root,COG5434@2|Bacteria,1MYQY@1224|Proteobacteria,1S167@1236|Gammaproteobacteria,469YA@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the glycosyl hydrolase 28 family - - - - - - - - - - - - - k141_33346_1 700598.Niako_0442 6.52e-27 107.0 COG3648@1|root,COG3648@2|Bacteria,4NKI1@976|Bacteroidetes,1IW04@117747|Sphingobacteriia 976|Bacteroidetes H Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin - - 1.7.3.3 ko:K00365 ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120 M00546 R02106,R07981 RC02107,RC02551 ko00000,ko00001,ko00002,ko01000 - - - Uricase k141_33346_2 55529.EKX45231 1.43e-18 79.7 COG2351@1|root,KOG3006@2759|Eukaryota 2759|Eukaryota A thyroid hormone binding - - 3.5.2.17 ko:K07127 ko00230,ko01100,ko01120,map00230,map01100,map01120 M00546 R06601 RC03393 ko00000,ko00001,ko00002,ko01000,ko02000 9.B.35.1.2,9.B.35.2 - - Transthyretin k141_3639_2 1492922.GY26_12330 1.12e-23 100.0 2DT26@1|root,33IBU@2|Bacteria,1NNDF@1224|Proteobacteria,1SSB3@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF4376) - - - - - - - - - - - - DUF4376 k141_3639_3 406817.XNC1_3065 2.3e-14 79.3 COG5301@1|root,COG5301@2|Bacteria,1MWNN@1224|Proteobacteria,1RR74@1236|Gammaproteobacteria 1236|Gammaproteobacteria M tail collar domain protein - - - - - - - - - - - - Collar,DUF3751,Phage_fiber_2 k141_32140_1 379066.GAU_2505 4.23e-18 80.1 COG5405@1|root,COG5405@2|Bacteria,1ZSVH@142182|Gemmatimonadetes 142182|Gemmatimonadetes O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery hslV - 3.4.25.2 ko:K01419 - - - - ko00000,ko01000,ko01002 - - - Proteasome k141_32140_2 880073.Calab_0163 4.63e-154 450.0 COG1220@1|root,COG1220@2|Bacteria,2NP00@2323|unclassified Bacteria 2|Bacteria O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis hslU GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019904,GO:0022607,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043335,GO:0043933,GO:0044085,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - ko:K03667 - - - - ko00000,ko03110 - - - AAA_2,ClpB_D2-small k141_15541_1 886293.Sinac_1691 2.48e-81 262.0 COG3379@1|root,COG3379@2|Bacteria,2IXA8@203682|Planctomycetes 203682|Planctomycetes S Type I phosphodiesterase / nucleotide pyrophosphatase - - - - - - - - - - - - Phosphodiest k141_27375_1 1042377.AFPJ01000030_gene508 1.5e-150 437.0 COG0226@1|root,COG2885@1|root,COG0226@2|Bacteria,COG2885@2|Bacteria,1MVXP@1224|Proteobacteria,1RNK7@1236|Gammaproteobacteria,46D11@72275|Alteromonadaceae 1236|Gammaproteobacteria MP PBP superfamily domain pstS - - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - OmpA,PBP_like_2 k141_27375_2 1279017.AQYJ01000023_gene3285 2.97e-175 494.0 COG2971@1|root,COG2971@2|Bacteria,1R41I@1224|Proteobacteria,1RPMK@1236|Gammaproteobacteria,466SH@72275|Alteromonadaceae 1236|Gammaproteobacteria G BadF/BadG/BcrA/BcrD ATPase family gspK GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0047931 2.7.1.8 ko:K18676 ko00520,ko01100,map00520,map01100 - R01961 RC00002,RC00017 ko00000,ko00001,ko01000 - - - BcrAD_BadFG k141_27375_3 1042377.AFPJ01000030_gene506 4.48e-207 577.0 COG2222@1|root,COG2222@2|Bacteria,1MXC7@1224|Proteobacteria,1RS53@1236|Gammaproteobacteria,46594@72275|Alteromonadaceae 1236|Gammaproteobacteria M SIS domain glmS1 - 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 - R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 - - - SIS k141_27375_4 1042377.AFPJ01000030_gene505 2.06e-210 588.0 COG1820@1|root,COG1820@2|Bacteria,1MW8Y@1224|Proteobacteria,1RMRV@1236|Gammaproteobacteria,465DK@72275|Alteromonadaceae 1236|Gammaproteobacteria G deacetylase nagA - 3.5.1.25 ko:K01443 ko00520,ko01130,map00520,map01130 - R02059 RC00166,RC00300 ko00000,ko00001,ko01000 - - - Amidohydro_1 k141_27375_5 1279017.AQYJ01000023_gene3288 4.18e-245 681.0 COG0738@1|root,COG0738@2|Bacteria,1MXDC@1224|Proteobacteria,1RMQJ@1236|Gammaproteobacteria,4654I@72275|Alteromonadaceae 1236|Gammaproteobacteria G Major Facilitator Superfamily gluP - - ko:K02429 - - - - ko00000,ko02000 2.A.1.7 - - MFS_1 k141_27375_7 1453501.JELR01000002_gene197 4.65e-281 781.0 COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,1RNIT@1236|Gammaproteobacteria,464TD@72275|Alteromonadaceae 1236|Gammaproteobacteria G Belongs to the GPI family pgi GO:0003674,GO:0003824,GO:0004347,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033554,GO:0034404,GO:0034599,GO:0034641,GO:0034654,GO:0034655,GO:0042221,GO:0042802,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0055086,GO:0070887,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 - - iEcSMS35_1347.EcSMS35_4486 PGI k141_84_1 42565.FP66_07525 1.63e-55 181.0 COG1186@1|root,COG1186@2|Bacteria,1MUAW@1224|Proteobacteria,1RP9Z@1236|Gammaproteobacteria,1XHPA@135619|Oceanospirillales 135619|Oceanospirillales J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA prfB - - ko:K02836 - - - - ko00000,ko03012 - - - PCRF,RF-1 k141_84_2 93220.LV28_23435 9.46e-23 98.6 COG1190@1|root,COG1190@2|Bacteria,1MX1V@1224|Proteobacteria,2VH1A@28216|Betaproteobacteria,1K1TR@119060|Burkholderiaceae 28216|Betaproteobacteria J Belongs to the class-II aminoacyl-tRNA synthetase family lysS - 6.1.1.6 ko:K04567 ko00970,map00970 M00359,M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2,tRNA_anti-codon k141_6006_1 1279017.AQYJ01000029_gene3406 0.0 1023.0 COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,1RPAV@1236|Gammaproteobacteria,463XQ@72275|Alteromonadaceae 1236|Gammaproteobacteria L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA ligA GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003909,GO:0003911,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0034645,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050662,GO:0050896,GO:0051103,GO:0051287,GO:0051716,GO:0070403,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1901576 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - iEC55989_1330.EC55989_2701,iECABU_c1320.ECABU_c27320,iECIAI1_1343.ECIAI1_2469,iECO103_1326.ECO103_2930,iECO111_1330.ECO111_3141,iECO26_1355.ECO26_3464,iECSE_1348.ECSE_2702,iECW_1372.ECW_m2640,iEKO11_1354.EKO11_1317,iEcE24377_1341.EcE24377A_2698,iEcSMS35_1347.EcSMS35_2566,iWFL_1372.ECW_m2640,iYL1228.KPN_02758,ic_1306.c2945 BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5 k141_6006_2 1279017.AQYJ01000029_gene3405 3.37e-98 303.0 COG3115@1|root,COG3115@2|Bacteria,1MVHR@1224|Proteobacteria,1RMDB@1236|Gammaproteobacteria,4673V@72275|Alteromonadaceae 1236|Gammaproteobacteria D Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins zipA GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0022402,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032506,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 - ko:K03528 - - - - ko00000,ko03036 - - - ZipA_C k141_6006_3 1453501.JELR01000001_gene2666 0.0 1367.0 COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,1RNA6@1236|Gammaproteobacteria,4645X@72275|Alteromonadaceae 1236|Gammaproteobacteria D Required for chromosome condensation and partitioning smc - - ko:K03529 - - - - ko00000,ko03036 - - - SMC_N,SMC_hinge k141_6006_4 1279017.AQYJ01000029_gene3403 1.08e-132 392.0 COG4235@1|root,COG4235@2|Bacteria,1MY4J@1224|Proteobacteria,1S358@1236|Gammaproteobacteria,466S6@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG4235 Cytochrome c biogenesis factor cycH - - ko:K02200 - - - - ko00000 - - - TPR_16,TPR_2 k141_17915_1 315730.BcerKBAB4_3463 5.04e-22 97.4 COG3646@1|root,COG3646@2|Bacteria,1V4HS@1239|Firmicutes,4HHX9@91061|Bacilli 91061|Bacilli K Phage regulatory protein Rha (Phage_pRha) - - - - - - - - - - - - ORF6C,Phage_pRha k141_17915_2 665950.HMPREF1025_00897 3.93e-05 44.7 29X9M@1|root,30IZ4@2|Bacteria,1UJWD@1239|Firmicutes,25FC2@186801|Clostridia,27PN4@186928|unclassified Lachnospiraceae 186801|Clostridia K Cro/C1-type HTH DNA-binding domain - - - - - - - - - - - - HTH_26 k141_17915_3 981383.AEWH01000001_gene3539 1.21e-30 109.0 29TDW@1|root,346YU@2|Bacteria,1VYX7@1239|Firmicutes,4HY6T@91061|Bacilli 91061|Bacilli S Cro/C1-type HTH DNA-binding domain - - - - - - - - - - - - HTH_26 k141_17915_12 66692.ABC2862 1.23e-78 240.0 2B9XI@1|root,323AV@2|Bacteria,1V7VV@1239|Firmicutes,4HK2T@91061|Bacilli,1ZMSA@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF1071) - - - - - - - - - - - - DUF1071 k141_17915_15 447909.A6M981_9VIRU 1.08e-62 198.0 4QBBN@10239|Viruses 10239|Viruses S Siphovirus Gp157 - - - - - - - - - - - - - k141_11938_1 218284.CCDN010000007_gene3838 1.13e-75 235.0 COG0477@1|root,COG2814@2|Bacteria,1TR1D@1239|Firmicutes,4HA4Z@91061|Bacilli,1ZB9Z@1386|Bacillus 91061|Bacilli EGP COG0477 Permeases of the major facilitator superfamily - - - ko:K05820 - - - - ko00000,ko02000 2.A.1.27 - - MFS_1_like k141_8412_1 218284.CCDN010000001_gene1042 3.46e-84 258.0 COG1686@1|root,COG1686@2|Bacteria,1TQN0@1239|Firmicutes,4HBCE@91061|Bacilli,1ZB0W@1386|Bacillus 91061|Bacilli M Belongs to the peptidase S11 family dacF GO:0003674,GO:0003824,GO:0004175,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.16.4 ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - PBP5_C,Peptidase_S11 k141_2459_2 1453501.JELR01000002_gene999 1.54e-71 215.0 COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,1S67I@1236|Gammaproteobacteria,467D0@72275|Alteromonadaceae 1236|Gammaproteobacteria K Belongs to the P(II) protein family glnK - - ko:K04751,ko:K04752 ko02020,map02020 - - - ko00000,ko00001 - - - P-II k141_16683_2 1279017.AQYJ01000028_gene2320 2.53e-49 173.0 COG0709@1|root,COG1252@1|root,COG0709@2|Bacteria,COG1252@2|Bacteria,1MWFG@1224|Proteobacteria,1RQ5Q@1236|Gammaproteobacteria,465WT@72275|Alteromonadaceae 1236|Gammaproteobacteria CE Belongs to the selenophosphate synthase 1 family. Class I subfamily - - 2.7.9.3 ko:K01008 ko00450,ko01100,map00450,map01100 - R03595 RC00002,RC02878 ko00000,ko00001,ko01000,ko03016 - - - AIRS,AIRS_C,Pyr_redox_2 k141_29769_1 1294265.JCM21738_162 1.21e-54 175.0 COG3331@1|root,COG3331@2|Bacteria,1V3S4@1239|Firmicutes,4HGZ7@91061|Bacilli,1ZCV9@1386|Bacillus 91061|Bacilli L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation recU GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - ko:K03700 - - - - ko00000,ko03400 - - - RecU k141_9570_2 1042377.AFPJ01000034_gene2377 2.66e-216 605.0 COG1364@1|root,COG1364@2|Bacteria,1MU0T@1224|Proteobacteria,1RNVF@1236|Gammaproteobacteria,464AB@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate argJ - 2.3.1.1,2.3.1.35 ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R00259,R02282 RC00004,RC00064 ko00000,ko00001,ko00002,ko01000 - - - ArgJ k141_9570_4 1453501.JELR01000001_gene3039 3.12e-201 560.0 COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,1RMIR@1236|Gammaproteobacteria,465Y3@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0739 Membrane proteins related to metalloendopeptidases - - - - - - - - - - - - Peptidase_M23 k141_26224_1 1453501.JELR01000001_gene2295 6.3e-21 90.5 COG2850@1|root,COG2850@2|Bacteria,1MW30@1224|Proteobacteria,1RN2Q@1236|Gammaproteobacteria,464Y7@72275|Alteromonadaceae 1236|Gammaproteobacteria S A domain family that is part of the cupin metalloenzyme superfamily. ycfD GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0016491,GO:0016705,GO:0016706,GO:0018193,GO:0018195,GO:0019538,GO:0030961,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046872,GO:0046914,GO:0051213,GO:0055114,GO:0071704,GO:1901564 1.14.11.47 ko:K18850 - - - - ko00000,ko01000,ko03009 - - - Cupin_4 k141_17916_1 441769.ABFU01000049_gene3702 4.85e-87 265.0 COG0672@1|root,COG0672@2|Bacteria,1TQIA@1239|Firmicutes,4HCJZ@91061|Bacilli,1ZDYA@1386|Bacillus 91061|Bacilli P COG0672 High-affinity Fe2 Pb2 permease - - - ko:K07243 - - - - ko00000,ko02000 2.A.108.1,2.A.108.2 - - FTR1 k141_10743_1 218284.CCDN010000005_gene3367 1.51e-56 193.0 COG5002@1|root,COG5002@2|Bacteria,1VUBP@1239|Firmicutes,4HUPW@91061|Bacilli,1ZS15@1386|Bacillus 91061|Bacilli T Histidine kinase kinE - 2.7.13.3 ko:K13533 ko02020,map02020 M00485 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9 k141_35729_1 1042209.HK44_021600 5.96e-153 441.0 COG3335@1|root,COG3335@2|Bacteria,1MW7X@1224|Proteobacteria,1RRMU@1236|Gammaproteobacteria,1YU3Y@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria L Endonuclease DDE - - - - - - - - - - - - DDE_3,HTH_23,HTH_28,HTH_32 k141_21481_1 218284.CCDN010000001_gene1238 1.08e-104 318.0 COG0477@1|root,COG2814@2|Bacteria,1VSW8@1239|Firmicutes,4HUQC@91061|Bacilli,1ZAS8@1386|Bacillus 91061|Bacilli EGP the major facilitator superfamily - - - - - - - - - - - - MFS_1 k141_34542_1 1294265.JCM21738_5412 2.28e-23 97.8 COG4187@1|root,COG4187@2|Bacteria,1TQQ7@1239|Firmicutes,4HABT@91061|Bacilli,1ZCEE@1386|Bacillus 91061|Bacilli E arginine degradation protein rocB - - - - - - - - - - - Peptidase_M20 k141_34542_2 1294265.JCM21738_5413 4.17e-194 549.0 COG0008@1|root,COG0008@2|Bacteria,1TP8G@1239|Firmicutes,4HBN6@91061|Bacilli,1ZCFK@1386|Bacillus 91061|Bacilli J COG0008 Glutamyl- and glutaminyl-tRNA synthetases glnS - 6.1.1.18 ko:K01886 ko00970,ko01100,map00970,map01100 M00359,M00360 R03652 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1c,tRNA-synt_1c_C k141_11956_2 218284.CCDN010000003_gene2996 1.23e-70 214.0 COG2919@1|root,COG2919@2|Bacteria,1VKC5@1239|Firmicutes,4HR53@91061|Bacilli,1ZIBZ@1386|Bacillus 91061|Bacilli D Septum formation initiator divIC - - ko:K13052 - - - - ko00000,ko03036 - - - DivIC k141_23832_1 1250278.JQNQ01000001_gene3113 3.15e-32 126.0 COG5000@1|root,COG5000@2|Bacteria,4NEWF@976|Bacteroidetes,1HYPN@117743|Flavobacteriia 976|Bacteroidetes T Histidine kinase - - - - - - - - - - - - HATPase_c k141_31007_2 42565.FP66_06465 1.46e-22 95.5 COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,1RPYH@1236|Gammaproteobacteria,1XH56@135619|Oceanospirillales 135619|Oceanospirillales K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoC - 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 k141_13184_1 1042377.AFPJ01000043_gene847 5.74e-17 79.3 COG0502@1|root,COG0502@2|Bacteria,1MVFF@1224|Proteobacteria,1RMEQ@1236|Gammaproteobacteria,46540@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism bioB GO:0003674,GO:0003824,GO:0004076,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.6 ko:K01012 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R01078 RC00441 ko00000,ko00001,ko00002,ko01000 - - iZ_1308.Z0994 BATS,Radical_SAM k141_13184_2 686578.AFFX01000003_gene328 1.16e-40 146.0 COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,1S64Q@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Competence protein gntX GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0015976,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 - - - - - - - - - - Pribosyltran k141_35745_1 218284.CCDN010000002_gene2042 3.01e-100 298.0 COG1131@1|root,COG1131@2|Bacteria,1TPQW@1239|Firmicutes,4HA3P@91061|Bacilli,1ZCNQ@1386|Bacillus 91061|Bacilli V ABC transporter, ATP-binding protein potA5 - - ko:K01990,ko:K16921 ko02010,map02010 M00254,M00584 - - ko00000,ko00001,ko00002,ko02000 3.A.1 - - ABC_tran k141_35745_2 218284.CCDN010000002_gene2043 2.46e-77 231.0 COG1725@1|root,COG1725@2|Bacteria,1VFD0@1239|Firmicutes,4HNIT@91061|Bacilli,1ZQA5@1386|Bacillus 91061|Bacilli K Transcriptional regulator ytrA - - ko:K07979 - - - - ko00000,ko03000 - - - GntR k141_25022_1 218284.CCDN010000001_gene1736 3.5e-87 273.0 COG0075@1|root,COG3916@1|root,COG0075@2|Bacteria,COG3916@2|Bacteria,1TR3I@1239|Firmicutes,4HA6W@91061|Bacilli,1ZAT2@1386|Bacillus 91061|Bacilli E Aminotransferase class-V - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10,Acetyltransf_5,Acetyltransf_9,Aminotran_5 k141_9588_1 218284.CCDN010000011_gene4426 7.76e-195 541.0 COG3711@1|root,COG3711@2|Bacteria,1TQJJ@1239|Firmicutes,4HBB3@91061|Bacilli,1ZBDU@1386|Bacillus 91061|Bacilli K antiterminator glcT - - ko:K03480,ko:K03488 - - - - ko00000,ko03000 - - - CAT_RBD,PRD k141_28629_1 1419583.V466_00210 4.66e-11 67.8 COG3547@1|root,COG3547@2|Bacteria,1MXKJ@1224|Proteobacteria,1RSCP@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Transposase - - - - - - - - - - - - DEDD_Tnp_IS110,Transposase_20 k141_7197_1 1042377.AFPJ01000014_gene1647 7.13e-153 436.0 COG0795@1|root,COG0795@2|Bacteria,1MVW3@1224|Proteobacteria,1RM8H@1236|Gammaproteobacteria,465SX@72275|Alteromonadaceae 1236|Gammaproteobacteria S permease lptG - - ko:K11720 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko02000 1.B.42.1 - - YjgP_YjgQ k141_21505_1 218284.CCDN010000008_gene4169 1.25e-134 394.0 COG1866@1|root,COG1866@2|Bacteria,1TPQV@1239|Firmicutes,4HAKG@91061|Bacilli,1ZCVN@1386|Bacillus 91061|Bacilli C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA pckA GO:0000166,GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0017076,GO:0019318,GO:0019319,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576 4.1.1.49 ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 M00003,M00170 R00341 RC00002,RC02741 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS09060,iYO844.BSU30560 PEPCK_ATP k141_6039_1 485913.Krac_4124 1.05e-18 90.1 COG0793@1|root,COG0793@2|Bacteria 2|Bacteria M Belongs to the peptidase S41A family - - - - - - - - - - - - Peptidase_S41 k141_22684_1 1116375.VEJY3_07720 2.14e-72 217.0 COG2920@1|root,COG2920@2|Bacteria,1RGVG@1224|Proteobacteria,1S5ZA@1236|Gammaproteobacteria,1XXBF@135623|Vibrionales 135623|Vibrionales P part of a sulfur-relay system tusE - - ko:K11179 ko04122,map04122 - - - ko00000,ko00001,ko01000,ko03016 - - - DsrC k141_4848_1 1117647.M5M_11060 9.12e-06 48.9 COG3639@1|root,COG3639@2|Bacteria,1N3HU@1224|Proteobacteria,1RYH5@1236|Gammaproteobacteria,1J7WT@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P COG3639 ABC-type phosphate phosphonate transport system, permease component phnE - - ko:K02042 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - BPD_transp_1 k141_4848_2 1323663.AROI01000023_gene1467 1.55e-53 171.0 COG3152@1|root,COG3152@2|Bacteria,1MZJ4@1224|Proteobacteria,1SA1N@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Membrane yhaH GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - DUF805 k141_4848_3 272558.10173007 6.13e-06 49.3 COG2169@1|root,COG2169@2|Bacteria,1V3Y7@1239|Firmicutes,4HCPZ@91061|Bacilli,1ZPXM@1386|Bacillus 91061|Bacilli K Metal binding domain of Ada adaA1 - - ko:K13530 - - - - ko00000,ko01000,ko03000,ko03400 - - - Ada_Zn_binding,HTH_18,HTH_AraC k141_26590_1 218284.CCDN010000001_gene694 3.34e-142 411.0 COG1559@1|root,COG1559@2|Bacteria,1TS48@1239|Firmicutes,4HAUV@91061|Bacilli,1ZC44@1386|Bacillus 91061|Bacilli S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation mltG - - ko:K07082 - - - - ko00000 - - - YceG k141_9769_4 1219080.VEZ01S_25_00250 2.57e-63 196.0 COG0346@1|root,COG0346@2|Bacteria,1RH8G@1224|Proteobacteria,1S629@1236|Gammaproteobacteria,1XXM8@135623|Vibrionales 135623|Vibrionales E COG0346 Lactoylglutathione lyase and related lyases - - - - - - - - - - - - Glyoxalase k141_9769_5 911045.PSE_1283 6.4e-62 200.0 28IZQ@1|root,2Z8X1@2|Bacteria,1R7RF@1224|Proteobacteria,2UJ99@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - DUF4386 k141_9769_6 203122.Sde_1709 4.81e-65 207.0 COG1082@1|root,COG1082@2|Bacteria,1RB2C@1224|Proteobacteria,1S292@1236|Gammaproteobacteria,466F9@72275|Alteromonadaceae 1236|Gammaproteobacteria G Xylose isomerase-like TIM barrel - - - - - - - - - - - - AP_endonuc_2 k141_8615_1 1453501.JELR01000002_gene341 6.28e-114 363.0 COG2885@1|root,COG2885@2|Bacteria,1QW22@1224|Proteobacteria,1T4AK@1236|Gammaproteobacteria,46ACU@72275|Alteromonadaceae 1236|Gammaproteobacteria M OmpA family - - - - - - - - - - - - DUF11,OmpA k141_18183_1 218284.CCDN010000007_gene3953 7.06e-41 145.0 COG1502@1|root,COG1502@2|Bacteria,1USPT@1239|Firmicutes,4HCJD@91061|Bacilli,1ZC77@1386|Bacillus 91061|Bacilli I Belongs to the phospholipase D family. Cardiolipin synthase subfamily clsB GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0032048,GO:0032049,GO:0032502,GO:0043934,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 - ko:K06131 ko00564,ko01100,map00564,map01100 - R07390 RC00017 ko00000,ko00001,ko01000 - - - PLDc_2 k141_18183_2 1347369.CCAD010000090_gene2001 6.32e-23 95.9 COG4294@1|root,COG4294@2|Bacteria,1TTCB@1239|Firmicutes,4H9PY@91061|Bacilli,1ZCJ7@1386|Bacillus 91061|Bacilli L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion uvsE - - ko:K13281 - - - - ko00000,ko01000 - - - UvdE k141_26591_1 1246484.D479_12103 6.56e-54 178.0 COG1708@1|root,COG1708@2|Bacteria,1V16I@1239|Firmicutes,4IS0S@91061|Bacilli 91061|Bacilli S Domain of unknown function (DUF4037) - - - - - - - - - - - - DUF4037 k141_21699_2 1453501.JELR01000002_gene1195 1.77e-191 535.0 COG0583@1|root,COG0583@2|Bacteria,1MVA1@1224|Proteobacteria,1RPAJ@1236|Gammaproteobacteria,46628@72275|Alteromonadaceae 1236|Gammaproteobacteria K transcriptional regulator oxyR - - ko:K04761 ko02026,map02026 - - - ko00000,ko00001,ko03000 - - - HTH_1,LysR_substrate k141_21699_3 1453501.JELR01000002_gene1196 3.95e-30 108.0 COG2261@1|root,COG2261@2|Bacteria,1N72W@1224|Proteobacteria,1S8YP@1236|Gammaproteobacteria,46BPP@72275|Alteromonadaceae 1236|Gammaproteobacteria S Transglycosylase associated protein yeaQ - - - - - - - - - - - Transgly_assoc k141_21699_4 1279017.AQYJ01000027_gene1880 5.27e-170 479.0 COG0451@1|root,COG0451@2|Bacteria,1MWVJ@1224|Proteobacteria,1RNDT@1236|Gammaproteobacteria,4673H@72275|Alteromonadaceae 1236|Gammaproteobacteria GM COG0451 Nucleoside-diphosphate-sugar epimerases - - - - - - - - - - - - Epimerase,NAD_binding_10,RmlD_sub_bind k141_21699_5 1453501.JELR01000002_gene1198 7.92e-63 194.0 COG0251@1|root,COG0251@2|Bacteria,1MZ3J@1224|Proteobacteria,1S5XS@1236|Gammaproteobacteria,4679E@72275|Alteromonadaceae 1236|Gammaproteobacteria J translation initiation inhibitor, yjgF family tdcF - - - - - - - - - - - Ribonuc_L-PSP k141_14520_1 1116375.VEJY3_11050 0.0 1086.0 COG3083@1|root,COG3083@2|Bacteria,1MX6X@1224|Proteobacteria,1RPAU@1236|Gammaproteobacteria,1XVE8@135623|Vibrionales 135623|Vibrionales S hydrolase of alkaline phosphatase superfamily - - - ko:K07014 - - - - ko00000 - - - DUF3413,Sulfatase k141_14520_2 223926.28807122 2.99e-43 141.0 COG3082@1|root,COG3082@2|Bacteria,1MZ9I@1224|Proteobacteria,1S8XQ@1236|Gammaproteobacteria,1XYB0@135623|Vibrionales 135623|Vibrionales S Belongs to the UPF0352 family yejL - - ko:K09904 - - - - ko00000 - - - DUF1414 k141_14520_3 1219076.N646_1247 1.06e-234 646.0 COG3081@1|root,COG3081@2|Bacteria,1NXJU@1224|Proteobacteria,1RP8N@1236|Gammaproteobacteria,1XU12@135623|Vibrionales 135623|Vibrionales S Nucleoid-associated protein yejK - - ko:K06899 - - - - ko00000,ko03036 - - - NA37 k141_14520_6 1116375.VEJY3_11030 3.51e-212 593.0 28MJ4@1|root,2ZAVQ@2|Bacteria,1R62K@1224|Proteobacteria,1RNQC@1236|Gammaproteobacteria,1XU5P@135623|Vibrionales 135623|Vibrionales - - VP2126 - - - - - - - - - - - - k141_14520_7 1219076.N646_1243 2e-263 722.0 COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,1RMN3@1236|Gammaproteobacteria,1XTI7@135623|Vibrionales 135623|Vibrionales E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate asd1 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004073,GO:0006082,GO:0006520,GO:0006549,GO:0006553,GO:0006555,GO:0006566,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009081,GO:0009082,GO:0009085,GO:0009086,GO:0009088,GO:0009089,GO:0009097,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC k141_14520_8 1042375.AFPL01000023_gene1674 3.09e-38 158.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - CZB,EAL,GAF_2,GGDEF,PAS_3,PAS_4,PAS_9,Protoglobin k141_14520_9 223926.28807116 1.68e-174 490.0 COG2126@1|root,COG2126@2|Bacteria,1MXCS@1224|Proteobacteria,1RPCN@1236|Gammaproteobacteria,1XTRC@135623|Vibrionales 135623|Vibrionales J COG1226 Kef-type K transport systems - - - ko:K10716 - - - - ko00000,ko02000 1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6 - - Ion_trans k141_14520_10 1116375.VEJY3_11010 5.85e-138 391.0 COG2095@1|root,COG2095@2|Bacteria,1MX5T@1224|Proteobacteria,1RPZ3@1236|Gammaproteobacteria,1XU2X@135623|Vibrionales 135623|Vibrionales U UPF0056 membrane protein - - - ko:K05595 - - - - ko00000,ko02000 2.A.95.1 - - MarC k141_14520_11 1219076.N646_1240 0.0 1720.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,1RNBH@1236|Gammaproteobacteria,1XTSP@135623|Vibrionales 135623|Vibrionales C belongs to the iron- containing alcohol dehydrogenase family adhE - 1.1.1.1,1.2.1.10 ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 - R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 ko00000,ko00001,ko01000 - - - Aldedh,Fe-ADH k141_14520_12 223926.28807113 4.7e-140 398.0 COG1028@1|root,COG1028@2|Bacteria,1QJGM@1224|Proteobacteria,1THGE@1236|Gammaproteobacteria,1XVMG@135623|Vibrionales 135623|Vibrionales IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) VP2120 - - - - - - - - - - - adh_short k141_14520_13 223926.28807112 1.51e-102 298.0 2EIW7@1|root,33CMH@2|Bacteria,1NIEH@1224|Proteobacteria,1SGBR@1236|Gammaproteobacteria,1XSI3@135623|Vibrionales 135623|Vibrionales S Ribosomal S4P (gammaproteobacterial) VV1177 - - - - - - - - - - - Ribosomal_S4Pg k141_14520_14 223926.28807111 5.73e-144 405.0 COG0605@1|root,COG0605@2|Bacteria,1MVW2@1224|Proteobacteria,1RP7X@1236|Gammaproteobacteria,1XTPM@135623|Vibrionales 135623|Vibrionales C Destroys radicals which are normally produced within the cells and which are toxic to biological systems sodB - 1.15.1.1 ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 - - - ko00000,ko00001,ko01000 - - - Sod_Fe_C,Sod_Fe_N k141_14520_15 223926.28807110 8.97e-75 223.0 COG0278@1|root,COG0278@2|Bacteria,1MZ4V@1224|Proteobacteria,1S640@1236|Gammaproteobacteria,1XXC2@135623|Vibrionales 135623|Vibrionales C Belongs to the glutaredoxin family. Monothiol subfamily grxD - - ko:K07390 - - - - ko00000,ko03029,ko03110 - - - Glutaredoxin k141_14520_16 1219076.N646_1233 9.63e-226 624.0 COG0582@1|root,COG0582@2|Bacteria,1N45B@1224|Proteobacteria,1RNDM@1236|Gammaproteobacteria,1XUBJ@135623|Vibrionales 135623|Vibrionales L Phage integrase family - - - - - - - - - - - - Phage_integrase k141_14520_17 82995.CR62_19870 1.82e-26 105.0 2EPMM@1|root,33H88@2|Bacteria,1NJQ7@1224|Proteobacteria,1SIZU@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_14520_18 716541.ECL_00689 1.85e-112 338.0 2E2V6@1|root,32XWX@2|Bacteria,1N6M0@1224|Proteobacteria,1T1DE@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_14520_19 1202962.KB907150_gene1469 1.16e-76 240.0 COG1226@1|root,COG1226@2|Bacteria,1RBAK@1224|Proteobacteria,1S3S7@1236|Gammaproteobacteria 1236|Gammaproteobacteria P COG1226 Kef-type K transport systems - - - ko:K10716 - - - - ko00000,ko02000 1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6 - - Ion_trans,Ion_trans_2 k141_14520_20 1517681.HW45_01860 5.04e-187 541.0 COG1196@1|root,COG1196@2|Bacteria,1PEPJ@1224|Proteobacteria,1RQFX@1236|Gammaproteobacteria,1XW1A@135623|Vibrionales 135623|Vibrionales D T5orf172 - - - - - - - - - - - - DUF4041,T5orf172 k141_14520_21 1219076.N646_1228 3.49e-99 293.0 COG2932@1|root,COG2932@2|Bacteria,1NDB9@1224|Proteobacteria,1RNJS@1236|Gammaproteobacteria,1XXPH@135623|Vibrionales 135623|Vibrionales K Bacteriophage CI repressor C-terminal domain - - - - - - - - - - - - Phage_CI_C,Phage_CI_repr k141_14520_22 345073.VC395_A0193 9.79e-31 109.0 2AWX2@1|root,31NUK@2|Bacteria,1QKI8@1224|Proteobacteria,1TINF@1236|Gammaproteobacteria,1XZDC@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_14520_23 1219076.N646_1226 2.47e-77 235.0 2BX0J@1|root,30H36@2|Bacteria,1R6TW@1224|Proteobacteria,1RZIA@1236|Gammaproteobacteria,1XWQD@135623|Vibrionales 135623|Vibrionales S Phage regulatory protein CII (CP76) - - - - - - - - - - - - Phage_CP76 k141_14520_24 1219076.N646_1225 2.89e-56 177.0 2B76D@1|root,32088@2|Bacteria,1QK7E@1224|Proteobacteria,1TIAN@1236|Gammaproteobacteria,1XYRS@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_14520_25 1219076.N646_1224 3.27e-46 150.0 2AXMJ@1|root,31PMV@2|Bacteria,1QMB8@1224|Proteobacteria,1TJJQ@1236|Gammaproteobacteria,1Y1BS@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_14520_26 1219076.N646_1223 4.57e-37 125.0 2B58X@1|root,31NS4@2|Bacteria,1QKGA@1224|Proteobacteria,1TIKE@1236|Gammaproteobacteria,1XZA5@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_14520_28 675816.VIA_001530 0.0 1439.0 28HIF@1|root,2Z7TX@2|Bacteria,1MY24@1224|Proteobacteria,1RN69@1236|Gammaproteobacteria,1XWMY@135623|Vibrionales 135623|Vibrionales S Bacteriophage replication gene A protein (GPA) - - - - - - - - - - - - Phage_GPA k141_24060_1 42565.FP66_07440 3.03e-158 452.0 COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,1RMKQ@1236|Gammaproteobacteria,1XIHN@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine coaBC - 4.1.1.36,6.3.2.5 ko:K13038 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 - - - DFP,Flavoprotein k141_15777_2 665952.HMPREF1015_01435 2.5e-44 150.0 COG4194@1|root,COG4194@2|Bacteria,1V3Z3@1239|Firmicutes,4HHRK@91061|Bacilli,1ZG9F@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF1648) - - - - - - - - - - - - DUF1648 k141_34767_1 42565.FP66_03365 1.28e-56 187.0 COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,1RNKF@1236|Gammaproteobacteria,1XI6M@135619|Oceanospirillales 135619|Oceanospirillales P Ammonium transporter - - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - Ammonium_transp k141_34767_2 42565.FP66_03370 2.96e-59 183.0 COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,1S5ZU@1236|Gammaproteobacteria 1236|Gammaproteobacteria K at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA) glnB - - ko:K04751,ko:K04752 ko02020,map02020 - - - ko00000,ko00001 - - - P-II k141_35921_2 1294265.JCM21738_3477 8.24e-35 122.0 COG4821@1|root,COG4821@2|Bacteria,1VJUP@1239|Firmicutes,4HP1J@91061|Bacilli,1ZH7S@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF2529) ywjG - - - - - - - - - - - DUF2529 k141_8635_1 443255.SCLAV_2859 9.63e-38 140.0 COG0079@1|root,COG0079@2|Bacteria,2GJXS@201174|Actinobacteria 201174|Actinobacteria E May catalyze the transamination reaction in phenylalanine biosynthesis pat - 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k141_20448_1 1515746.HR45_01495 1.49e-127 392.0 COG1629@1|root,COG4771@2|Bacteria,1MUNK@1224|Proteobacteria,1RN9S@1236|Gammaproteobacteria,2Q9RT@267890|Shewanellaceae 1236|Gammaproteobacteria P TonB-dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_5050_1 1007105.PT7_0485 2.52e-07 56.2 COG0478@1|root,COG0478@2|Bacteria,1QUI1@1224|Proteobacteria,2WGVZ@28216|Betaproteobacteria,3T3Y2@506|Alcaligenaceae 28216|Betaproteobacteria H Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position kdkA - 2.7.1.166 ko:K11211 ko00540,map00540 - R09767 RC00002,RC00078 ko00000,ko00001,ko01000 - - - Kdo k141_26635_1 1120983.KB894571_gene2324 0.000677 42.0 COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,2TSUR@28211|Alphaproteobacteria,1JNTV@119043|Rhodobiaceae 28211|Alphaproteobacteria V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin uppP - 3.6.1.27 ko:K06153 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - BacA k141_6371_1 93220.LV28_10640 1.76e-40 154.0 COG0642@1|root,COG0642@2|Bacteria,1QTSX@1224|Proteobacteria,2VI80@28216|Betaproteobacteria,1K48Q@119060|Burkholderiaceae 28216|Betaproteobacteria T Histidine kinase - - 2.7.13.3 ko:K07649 ko02020,map02020 M00457 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - 2CSK_N,HATPase_c,HisKA k141_3945_1 1042377.AFPJ01000036_gene1142 7.55e-64 211.0 COG1680@1|root,COG1680@2|Bacteria,1MVZN@1224|Proteobacteria,1RP0R@1236|Gammaproteobacteria,468BI@72275|Alteromonadaceae 1236|Gammaproteobacteria V Beta-lactamase - - - - - - - - - - - - Beta-lactamase,DUF3471 k141_12288_1 1453501.JELR01000002_gene952 2.03e-121 388.0 COG0643@1|root,COG0745@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,4650G@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0643 Chemotaxis protein histidine kinase and related kinases chpA - - ko:K02487,ko:K06596 ko02020,ko02025,map02020,map02025 M00507 - - ko00000,ko00001,ko00002,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg k141_37087_1 1279017.AQYJ01000026_gene342 2.98e-161 453.0 COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,1RMHX@1236|Gammaproteobacteria,465IM@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the reversible phosphorylation of UMP to UDP pyrH - 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 - R00158 RC00002 ko00000,ko00001,ko01000 - - - AA_kinase k141_35922_1 218284.CCDN010000005_gene3380 6.74e-122 363.0 COG1164@1|root,COG1164@2|Bacteria,1TPV4@1239|Firmicutes,4HAJJ@91061|Bacilli,1ZD3W@1386|Bacillus 91061|Bacilli E oligoendopeptidase pepF - - - - - - - - - - - Peptidase_M3 k141_21719_1 218284.CCDN010000004_gene3144 3.17e-234 647.0 COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,4HAMQ@91061|Bacilli,1ZBDW@1386|Bacillus 91061|Bacilli P Belongs to the ABC transporter superfamily msmX - - ko:K10112 ko02010,map02010 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1 - - ABC_tran,TOBE,TOBE_2 k141_34768_1 251229.Chro_2427 6.86e-73 228.0 COG1174@1|root,COG1174@2|Bacteria,1G2ZA@1117|Cyanobacteria,3VNP6@52604|Pleurocapsales 1117|Cyanobacteria E Binding-protein-dependent transport system inner membrane component - - - ko:K05846 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - BPD_transp_1 k141_34768_2 572544.Ilyop_0545 2.34e-13 71.2 COG1732@1|root,COG1732@2|Bacteria,378QN@32066|Fusobacteria 32066|Fusobacteria P PFAM Substrate-binding region of ABC-type glycine betaine transport system - - - ko:K05845,ko:K05846 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - BPD_transp_1,OpuAC k141_31241_2 1294265.JCM21738_3498 5.37e-38 132.0 COG0047@1|root,COG0047@2|Bacteria,1TP1B@1239|Firmicutes,4HAKZ@91061|Bacilli,1ZB9C@1386|Bacillus 91061|Bacilli F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL purQ GO:0003674,GO:0003824,GO:0004642,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - GATase_5 k141_12289_1 218284.CCDN010000008_gene4067 2.53e-28 114.0 COG1404@1|root,COG2247@1|root,COG1404@2|Bacteria,COG2247@2|Bacteria,1TQ2M@1239|Firmicutes,4HB7D@91061|Bacilli,1ZAZE@1386|Bacillus 91061|Bacilli O Belongs to the peptidase S8 family - - - - - - - - - - - - CW_binding_2,Peptidase_S8 k141_3946_1 1303518.CCALI_00213 8.62e-11 62.0 COG0461@1|root,COG0461@2|Bacteria 2|Bacteria F orotate phosphoribosyltransferase activity pyrE - 2.4.2.10 ko:K00762 ko00240,ko01100,map00240,map01100 M00051 R01870 RC00611 ko00000,ko00001,ko00002,ko01000 - - - Pribosyltran k141_32318_1 218284.CCDN010000001_gene198 3.36e-134 387.0 COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,4HA13@91061|Bacilli,1ZAWQ@1386|Bacillus 91061|Bacilli E Aminotransferase patA - - ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 M00525 R04467 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k141_29952_2 749413.E5DV50_9VIRU 2.9e-114 339.0 4QC1Z@10239|Viruses,4QWFJ@35237|dsDNA viruses no RNA stage 10239|Viruses S Terminase-like family - - - - - - - - - - - - - k141_1445_1 1279017.AQYJ01000029_gene3456 1.82e-18 83.2 COG0847@1|root,COG0847@2|Bacteria,1MV8Z@1224|Proteobacteria,1RNHQ@1236|Gammaproteobacteria,46491@72275|Alteromonadaceae 1236|Gammaproteobacteria L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease dnaQ GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016787,GO:0016788,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0045004,GO:0045005,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7,3.1.26.4 ko:K02342,ko:K14159 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - RNase_H,RNase_T k141_1445_2 1279017.AQYJ01000029_gene3457 2.75e-207 586.0 COG3067@1|root,COG3067@2|Bacteria,1MV0F@1224|Proteobacteria,1RPE3@1236|Gammaproteobacteria,464PD@72275|Alteromonadaceae 1236|Gammaproteobacteria P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons nhaB GO:0003674,GO:0005215,GO:0005451,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0006873,GO:0006885,GO:0008150,GO:0008324,GO:0009987,GO:0010035,GO:0010038,GO:0010226,GO:0015075,GO:0015077,GO:0015078,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015491,GO:0015672,GO:0016020,GO:0019725,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030004,GO:0030641,GO:0034220,GO:0035725,GO:0042221,GO:0042592,GO:0044464,GO:0045851,GO:0046873,GO:0048878,GO:0050801,GO:0050896,GO:0051179,GO:0051234,GO:0051452,GO:0051453,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0098771,GO:0099516,GO:1902600 - ko:K03314 - - - - ko00000,ko02000 2.A.34.1 - iECP_1309.ECP_1229,iLF82_1304.LF82_1485,iNRG857_1313.NRG857_06055,iUTI89_1310.UTI89_C1372 NhaB k141_35923_1 379066.GAU_1955 1.16e-50 179.0 COG0317@1|root,COG0317@2|Bacteria,1ZT5M@142182|Gemmatimonadetes 142182|Gemmatimonadetes KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance - - 2.7.6.5 ko:K00951 ko00230,map00230 - R00429 RC00002,RC00078 ko00000,ko00001,ko01000 - - - ACT_4,HD_4,RelA_SpoT,TGS k141_31242_1 1131730.BAVI_16452 4.75e-38 143.0 COG3420@1|root,COG3420@2|Bacteria,1V3VE@1239|Firmicutes,4IRVZ@91061|Bacilli,1ZRYK@1386|Bacillus 91061|Bacilli P Periplasmic copper-binding protein (NosD) - - - ko:K07218 - - - - ko00000 - - - NosD k141_3948_2 1042377.AFPJ01000032_gene2757 3.01e-70 217.0 COG1051@1|root,COG1051@2|Bacteria 2|Bacteria F GDP-mannose mannosyl hydrolase activity - - 2.1.3.15,6.4.1.2 ko:K01962,ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - NUDIX k141_24064_2 1294265.JCM21738_1280 1.49e-29 116.0 COG5002@1|root,COG5002@2|Bacteria,1TPPQ@1239|Firmicutes,4HCZW@91061|Bacilli,1ZF21@1386|Bacillus 91061|Bacilli T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - 2.7.13.3 ko:K07642 ko02020,map02020 M00450,M00645,M00646,M00648 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA k141_5054_1 1047013.AQSP01000144_gene846 4.58e-13 73.6 COG0392@1|root,COG0392@2|Bacteria,2NPGZ@2323|unclassified Bacteria 2|Bacteria S Lysylphosphatidylglycerol synthase TM region mprF - - ko:K07027 - - - - ko00000,ko02000 4.D.2 - - LPG_synthase_TM k141_15778_1 1453501.JELR01000002_gene611 6.21e-59 188.0 COG0494@1|root,COG0494@2|Bacteria,1RDMW@1224|Proteobacteria,1RPZV@1236|Gammaproteobacteria,4670F@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes nudF GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019144,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0047631,GO:0050896 3.6.1.13 ko:K01515 ko00230,map00230 - R01054 RC00002 ko00000,ko00001,ko01000 - - iECP_1309.ECP_3126 NUDIX k141_15778_3 1042377.AFPJ01000024_gene763 4.03e-31 115.0 2DZ4B@1|root,34CDM@2|Bacteria,1PAEV@1224|Proteobacteria,1SV2F@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF4136) - - - - - - - - - - - - DUF4136 k141_405_1 1279017.AQYJ01000028_gene2304 2.54e-68 208.0 2E73W@1|root,331NB@2|Bacteria,1N81U@1224|Proteobacteria,1SCT8@1236|Gammaproteobacteria,467TV@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF2750) SO1991 - - - - - - - - - - - DUF2750 k141_405_2 1123073.KB899242_gene1212 5.49e-117 353.0 COG2265@1|root,COG2265@2|Bacteria,1MV3A@1224|Proteobacteria,1RN1D@1236|Gammaproteobacteria,1X4IP@135614|Xanthomonadales 135614|Xanthomonadales J Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA rlmD - 2.1.1.190 ko:K03215 - - - - ko00000,ko01000,ko03009 - - - TRAM,tRNA_U5-meth_tr k141_34770_1 529709.PYCH_09500 1.52e-97 294.0 COG0281@1|root,arCOG01331@2157|Archaea,2XTRZ@28890|Euryarchaeota,242SQ@183968|Thermococci 183968|Thermococci O Belongs to the peptidase M48B family htpX - - ko:K03799 - M00743 - - ko00000,ko00002,ko01000,ko01002 - - - Peptidase_M48 k141_21721_1 218284.CCDN010000001_gene1190 4.64e-84 254.0 COG1418@1|root,COG1418@2|Bacteria,1V7IZ@1239|Firmicutes,4HIVB@91061|Bacilli,1ZB0E@1386|Bacillus 91061|Bacilli S phosphohydrolase ypgQ - - ko:K06950 - - - - ko00000 - - - HD k141_26636_1 1279017.AQYJ01000024_gene863 1.91e-193 540.0 COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,1RMKP@1236|Gammaproteobacteria,4646V@72275|Alteromonadaceae 1236|Gammaproteobacteria J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs truB GO:0000049,GO:0001522,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0031119,GO:0034337,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990481 5.4.99.25 ko:K03177 - - - - ko00000,ko01000,ko03016 - - - TruB-C_2,TruB_C_2,TruB_N k141_18207_1 586413.CCDL010000001_gene765 8.94e-44 158.0 COG1199@1|root,COG1199@2|Bacteria,1TRNV@1239|Firmicutes,4HBYD@91061|Bacilli,23J4T@182709|Oceanobacillus 91061|Bacilli KL HELICc2 ypvA - 3.6.4.12 ko:K03722 - - - - ko00000,ko01000,ko03400 - - - Helicase_C_2 k141_26864_13 1042377.AFPJ01000051_gene35 3.61e-198 565.0 28HC9@1|root,2Z7P5@2|Bacteria,1R4BH@1224|Proteobacteria,1RSAN@1236|Gammaproteobacteria,4642U@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_11261_1 665959.HMPREF1013_00414 5e-105 313.0 29ECG@1|root,301AF@2|Bacteria,1UY4W@1239|Firmicutes,4HDX6@91061|Bacilli,1ZAV2@1386|Bacillus 91061|Bacilli M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR spoIIGA GO:0003674,GO:0003824,GO:0004175,GO:0004190,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016020,GO:0016021,GO:0016787,GO:0019538,GO:0031224,GO:0031226,GO:0043170,GO:0043621,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0070001,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 - ko:K06383 - - - - ko00000,ko01000,ko01002 - - - Peptidase_U4 k141_14687_1 1121878.AUGL01000017_gene1811 3.53e-31 128.0 COG2091@1|root,COG2091@2|Bacteria,1MY8E@1224|Proteobacteria,1RQAI@1236|Gammaproteobacteria 1236|Gammaproteobacteria H lysine biosynthetic process via aminoadipic acid - - - - - - - - - - - - CBM9_1 k141_27685_1 42565.FP66_05095 1.06e-148 434.0 COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,1RMJB@1236|Gammaproteobacteria,1XIIQ@135619|Oceanospirillales 135619|Oceanospirillales T GTP-binding protein TypA typA - - ko:K06207 - - - - ko00000 - - - EFG_C,GTP_EFTU,GTP_EFTU_D2 k141_36056_1 218284.CCDN010000001_gene1668 5.06e-112 344.0 COG3973@1|root,COG3973@2|Bacteria,1TP39@1239|Firmicutes,4H9Y5@91061|Bacilli,1ZAWP@1386|Bacillus 91061|Bacilli L DNA helicase uvrD - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_19,UvrD-helicase,UvrD_C,UvrD_C_2 k141_8889_1 218284.CCDN010000001_gene1343 5.96e-132 385.0 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4HB97@91061|Bacilli,1ZBGZ@1386|Bacillus 91061|Bacilli C Belongs to the aldehyde dehydrogenase family - - 1.2.1.3 ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_24213_1 218284.CCDN010000005_gene3263 6.29e-120 347.0 COG1073@1|root,COG1073@2|Bacteria,1TTC0@1239|Firmicutes,4HBCG@91061|Bacilli,1ZBIJ@1386|Bacillus 91061|Bacilli S COG1073 Hydrolases of the alpha beta superfamily yitV - - ko:K06889 - - - - ko00000 - - - Abhydrolase_1,Hydrolase_4,Peptidase_S9 k141_21893_1 360094.PXO_02732 4.73e-06 45.1 COG1943@1|root,COG1943@2|Bacteria 2|Bacteria L Transposase - - - - - - - - - - - - Y1_Tnp k141_10098_1 261292.Nit79A3_3483 2.36e-32 126.0 COG0695@1|root,COG0695@2|Bacteria,1QVSK@1224|Proteobacteria,2VH4R@28216|Betaproteobacteria 28216|Betaproteobacteria O PFAM Glutaredoxin - - - - - - - - - - - - Glutaredoxin k141_20663_1 861299.J421_2767 3.11e-98 320.0 COG0085@1|root,COG0085@2|Bacteria,1ZSQH@142182|Gemmatimonadetes 142182|Gemmatimonadetes K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoB - 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 k141_13714_1 1392488.JHZY01000004_gene3537 1.28e-49 173.0 COG0415@1|root,COG0415@2|Bacteria,4NDW0@976|Bacteroidetes,1HWUN@117743|Flavobacteriia,2XIPJ@283735|Leeuwenhoekiella 976|Bacteroidetes L DNA photolyase phrB3 - 4.1.99.3 ko:K01669 - - - - ko00000,ko01000,ko03400 - - - DNA_photolyase,FAD_binding_7 k141_13714_2 1279017.AQYJ01000028_gene2146 2.47e-181 516.0 COG1804@1|root,COG1804@2|Bacteria,1MW1H@1224|Proteobacteria,1RN9B@1236|Gammaproteobacteria,46AHI@72275|Alteromonadaceae 1236|Gammaproteobacteria C acyl-CoA transferases carnitine dehydratase - - - - - - - - - - - - CoA_transf_3 k141_5316_1 1294265.JCM21738_2821 2.11e-90 267.0 294NZ@1|root,2ZS2A@2|Bacteria,1V3ME@1239|Firmicutes,4HHEZ@91061|Bacilli,1ZFT3@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_5316_2 1347086.CCBA010000004_gene4457 4.53e-36 132.0 COG4972@1|root,COG4972@2|Bacteria,1TSTJ@1239|Firmicutes,4HD01@91061|Bacilli,1ZCYF@1386|Bacillus 91061|Bacilli NU Pilus assembly protein - - - ko:K18640 - - - - ko00000,ko04812 - - - StbA k141_15917_1 398511.BpOF4_16330 8.55e-34 123.0 COG1670@1|root,COG1670@2|Bacteria,1TQS3@1239|Firmicutes,4HDCG@91061|Bacilli,1ZETV@1386|Bacillus 91061|Bacilli J Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_3 k141_34986_1 1453501.JELR01000002_gene511 4.97e-91 280.0 COG2133@1|root,COG2133@2|Bacteria,1MVK5@1224|Proteobacteria,1RPE8@1236|Gammaproteobacteria,4665U@72275|Alteromonadaceae 1236|Gammaproteobacteria G COG2133 Glucose sorbosone dehydrogenases - - - - - - - - - - - - GSDH k141_12571_1 218284.CCDN010000004_gene3127 4.66e-124 364.0 COG0044@1|root,COG0044@2|Bacteria,1TPI6@1239|Firmicutes,4HAA9@91061|Bacilli,1ZE4P@1386|Bacillus 91061|Bacilli F Catalyzes the hydrolytic cleavage of a subset of L- isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation iadA - - ko:K01305 - - - - ko00000,ko01000,ko01002 - - - Amidohydro_1,Amidohydro_3 k141_17114_1 218284.CCDN010000001_gene150 2.09e-57 187.0 COG0726@1|root,COG0726@2|Bacteria,1TS3D@1239|Firmicutes,4HAVF@91061|Bacilli,1ZC37@1386|Bacillus 91061|Bacilli G Polysaccharide deacetylase pdaA_2 - 3.5.1.104 ko:K01567,ko:K22278 - - - - ko00000,ko01000 - - - Polysacc_deac_1 k141_20664_1 313628.LNTAR_23259 4.3e-36 136.0 COG3547@1|root,COG3547@2|Bacteria 2|Bacteria L Transposase (IS116 IS110 IS902 family) - - - - - - - - - - - - DEDD_Tnp_IS110,Transposase_20 k141_32460_1 218284.CCDN010000001_gene1512 2.75e-79 244.0 COG0709@1|root,COG0709@2|Bacteria,1TQCJ@1239|Firmicutes,4HB6P@91061|Bacilli,1ZCAH@1386|Bacillus 91061|Bacilli E Synthesizes selenophosphate from selenide and ATP selD - 2.7.9.3 ko:K01008 ko00450,ko01100,map00450,map01100 - R03595 RC00002,RC02878 ko00000,ko00001,ko01000,ko03016 - - - AIRS,AIRS_C k141_27686_1 562743.JH976441_gene440 5.28e-26 99.8 COG0290@1|root,COG0290@2|Bacteria,1V1RC@1239|Firmicutes,4HFUS@91061|Bacilli 91061|Bacilli J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins infC GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - ko:K02520 - - - - ko00000,ko03012,ko03029 - - - IF3_C,IF3_N k141_19532_1 1453501.JELR01000001_gene3074 6.35e-103 308.0 COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,4645J@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain degS GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009897,GO:0009986,GO:0009987,GO:0010033,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031975,GO:0033554,GO:0035966,GO:0035967,GO:0042221,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051716,GO:0051788,GO:0070011,GO:0070887,GO:0071218,GO:0071310,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0140096,GO:1901564 - ko:K04691,ko:K04772 - - - - ko00000,ko01000,ko01002 - - - PDZ_2,Trypsin_2 k141_19532_2 1042377.AFPJ01000034_gene2339 5.51e-28 105.0 2CD3D@1|root,32RWZ@2|Bacteria,1N61G@1224|Proteobacteria,1SB8Q@1236|Gammaproteobacteria,46BJ4@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF4440) - - - - - - - - - - - - DUF4440 k141_25534_1 218284.CCDN010000002_gene2097 1.16e-81 249.0 COG0714@1|root,COG0714@2|Bacteria,1TPKR@1239|Firmicutes,4HA0T@91061|Bacilli,1ZC0I@1386|Bacillus 91061|Bacilli S ATPase family associated with various cellular activities (AAA) - - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 k141_26867_1 1294265.JCM21738_4525 1.84e-26 107.0 2BZRV@1|root,2Z8AV@2|Bacteria,1UX40@1239|Firmicutes,4HAVP@91061|Bacilli,1ZDM4@1386|Bacillus 91061|Bacilli S Nuclease-related domain - - - - - - - - - - - - NERD k141_23192_2 203122.Sde_3564 9.72e-11 60.8 2DRME@1|root,33C9X@2|Bacteria,1NHQS@1224|Proteobacteria,1SH9S@1236|Gammaproteobacteria,468YE@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_23192_3 349521.HCH_02603 7.37e-26 106.0 COG0457@1|root,COG0457@2|Bacteria,1NB8N@1224|Proteobacteria,1SEZN@1236|Gammaproteobacteria,1XMRE@135619|Oceanospirillales 135619|Oceanospirillales S FOG TPR repeat - - - - - - - - - - - - TPR_11,TPR_6,TPR_8 k141_23192_4 1279017.AQYJ01000028_gene2074 1.49e-53 191.0 COG1729@1|root,COG1729@2|Bacteria,1MX82@1224|Proteobacteria,1T32S@1236|Gammaproteobacteria,465Q0@72275|Alteromonadaceae 1236|Gammaproteobacteria O protein conserved in bacteria - - - - - - - - - - - - TPR_16,TPR_6,TPR_8,YfiO k141_24215_2 42565.FP66_12930 1.94e-92 275.0 COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,1RMBB@1236|Gammaproteobacteria,1XHUP@135619|Oceanospirillales 135619|Oceanospirillales IQ Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis fabG - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 k141_11263_2 218284.CCDN010000001_gene934 1.4e-34 124.0 COG4940@1|root,COG4940@2|Bacteria,1VKRP@1239|Firmicutes,4HR6S@91061|Bacilli,1ZIZV@1386|Bacillus 91061|Bacilli U COG4940 Competence protein ComGF comGF - - ko:K02248 - M00429 - - ko00000,ko00002,ko02044 - - - ComGF,N_methyl k141_12572_1 1294265.JCM21738_947 1.44e-127 365.0 COG0133@1|root,COG0133@2|Bacteria,1TPI3@1239|Firmicutes,4H9WC@91061|Bacilli,1ZCBT@1386|Bacillus 91061|Bacilli E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine trpB GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20,5.3.1.24 ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722,R03509 RC00209,RC00210,RC00700,RC00701,RC00945,RC02868 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU22640 PALP k141_23193_1 1121091.AUMP01000001_gene572 2.91e-23 91.7 2EEW1@1|root,338PF@2|Bacteria,1VIRW@1239|Firmicutes,4HP92@91061|Bacilli 91061|Bacilli S Membrane-integrating protein Mistic mstX - - - - - - - - - - - Mistic k141_20666_1 1453501.JELR01000001_gene1885 6.07e-134 391.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,465UR@72275|Alteromonadaceae 1236|Gammaproteobacteria C Belongs to the aldehyde dehydrogenase family - - 1.2.1.3 ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_31357_2 1453501.JELR01000001_gene1910 2.86e-81 247.0 COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,1RP9U@1236|Gammaproteobacteria,467BW@72275|Alteromonadaceae 1236|Gammaproteobacteria M PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides ppiA GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005623,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 ko:K01802,ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 - - - ko00000,ko00001,ko01000,ko03110,ko04147 - - - Pro_isomerase k141_31357_3 203122.Sde_1715 4.29e-39 142.0 COG3807@1|root,COG3807@2|Bacteria,1QWZW@1224|Proteobacteria,1T31J@1236|Gammaproteobacteria,467XH@72275|Alteromonadaceae 1236|Gammaproteobacteria S SH3 domain protein ygiM - - ko:K07184 - - - - ko00000 - - - SH3_3 k141_15919_1 1168065.DOK_17535 3.12e-49 159.0 COG4633@1|root,COG4633@2|Bacteria,1N6VB@1224|Proteobacteria,1SDG5@1236|Gammaproteobacteria,1J6RB@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Cupredoxin-like domain - - - - - - - - - - - - Cupredoxin_1 k141_15919_2 1045855.DSC_04340 9.84e-11 64.3 COG0642@1|root,COG2205@2|Bacteria,1N1Z2@1224|Proteobacteria,1RPG9@1236|Gammaproteobacteria,1X54G@135614|Xanthomonadales 135614|Xanthomonadales T COG0642 Signal transduction histidine kinase - - 2.7.13.3 ko:K07645 ko02020,ko02024,map02020,map02024 M00453 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - 2CSK_N,HATPase_c,HisKA k141_34987_1 1453501.JELR01000005_gene1569 2.04e-96 319.0 COG1361@1|root,COG3210@1|root,COG1361@2|Bacteria,COG3210@2|Bacteria,1QUXB@1224|Proteobacteria,1T5IP@1236|Gammaproteobacteria 1236|Gammaproteobacteria MU Domain of unknown function (DUF4347) - - - - - - - - - - - - DUF11,DUF4347 k141_34987_2 1453501.JELR01000005_gene1568 2.9e-96 289.0 COG2207@1|root,COG2207@2|Bacteria,1MX23@1224|Proteobacteria,1RRXM@1236|Gammaproteobacteria,4684C@72275|Alteromonadaceae 1236|Gammaproteobacteria K Arabinose-binding domain of AraC transcription regulator, N-term - - - - - - - - - - - - Arabinose_bd,HTH_18 k141_27688_2 991905.SL003B_3079 3.27e-10 60.1 COG4108@1|root,COG4108@2|Bacteria,1MU7X@1224|Proteobacteria,2TRP5@28211|Alphaproteobacteria,4BPWM@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP prfC - - ko:K02837 - - - - ko00000,ko03012 - - - GTP_EFTU,GTP_EFTU_D2,RF3_C k141_5318_2 246197.MXAN_2139 5.34e-70 217.0 COG3791@1|root,COG3791@2|Bacteria,1RCXS@1224|Proteobacteria,4355X@68525|delta/epsilon subdivisions,2WZGU@28221|Deltaproteobacteria,2Z24D@29|Myxococcales 28221|Deltaproteobacteria S Glutathione-dependent formaldehyde-activating - - - - - - - - - - - - - k141_6490_1 320841.Q4ZC74_9CAUD 7.98e-58 195.0 4QAR7@10239|Viruses,4QUW5@35237|dsDNA viruses no RNA stage,4QPKJ@28883|Caudovirales,4QKQ3@10699|Siphoviridae 10699|Siphoviridae S Phage portal protein, SPP1 Gp6-like - GO:0005575,GO:0019012,GO:0019028,GO:0032991,GO:0044423,GO:0046729,GO:0046798 - - - - - - - - - - - k141_37268_1 1294265.JCM21738_1898 1.58e-33 122.0 COG2323@1|root,COG2323@2|Bacteria,1TRWQ@1239|Firmicutes,4H9VA@91061|Bacilli,1ZCPH@1386|Bacillus 91061|Bacilli S membrane - - - - - - - - - - - - DUF1657,DUF421 k141_24217_1 1453501.JELR01000002_gene1322 1.17e-128 372.0 COG2197@1|root,COG2197@2|Bacteria 2|Bacteria K response regulator - - - - - - - - - - - - GerE,PAS_3 k141_12573_1 218284.CCDN010000001_gene1373 9.69e-146 416.0 COG0614@1|root,COG0614@2|Bacteria,1UNE3@1239|Firmicutes,4H9ZX@91061|Bacilli,1ZBS8@1386|Bacillus 91061|Bacilli P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component yvrC - - ko:K02016 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - Peripla_BP_2 k141_25537_1 1279017.AQYJ01000025_gene609 9.51e-143 411.0 COG2355@1|root,COG2355@2|Bacteria,1MWEW@1224|Proteobacteria,1RYET@1236|Gammaproteobacteria,469YE@72275|Alteromonadaceae 1236|Gammaproteobacteria E Membrane dipeptidase (Peptidase family M19) - - - - - - - - - - - - Peptidase_M19 k141_36059_1 218284.CCDN010000005_gene3402 9.35e-51 170.0 COG2206@1|root,COG2206@2|Bacteria,1TQIM@1239|Firmicutes,4HBV6@91061|Bacilli,1ZCMY@1386|Bacillus 91061|Bacilli T HD domain cnpD3 - - - - - - - - - - - HD,HD_5 k141_18416_2 1307436.PBF_04355 1.73e-170 482.0 COG4653@1|root,COG4653@2|Bacteria,1UZMZ@1239|Firmicutes,4HBKI@91061|Bacilli,1ZEHH@1386|Bacillus 91061|Bacilli S Phage capsid family - - - - - - - - - - - - Phage_capsid k141_18416_4 279010.BL00974 3.64e-45 148.0 2EK8A@1|root,33DYN@2|Bacteria,1VKUA@1239|Firmicutes,4HSSM@91061|Bacilli,1ZP4N@1386|Bacillus 91061|Bacilli S Phage gp6-like head-tail connector protein - - - - - - - - - - - - Phage_connect_1 k141_18416_6 279010.BL05128 3.49e-35 125.0 2DNPK@1|root,32YFU@2|Bacteria,1VFCK@1239|Firmicutes,4HQNX@91061|Bacilli,1ZK6M@1386|Bacillus 91061|Bacilli S Bacteriophage HK97-gp10, putative tail-component - - - - - - - - - - - - HK97-gp10_like k141_12584_1 218284.CCDN010000002_gene2201 6.88e-212 590.0 COG4362@1|root,COG4362@2|Bacteria,1TRDM@1239|Firmicutes,4HAR0@91061|Bacilli,1ZB33@1386|Bacillus 91061|Bacilli C Belongs to the NOS family. Bacterial NOS oxygenase subfamily nos GO:0001505,GO:0003674,GO:0003824,GO:0004497,GO:0004517,GO:0006807,GO:0006809,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016705,GO:0016709,GO:0017144,GO:0034641,GO:0042133,GO:0042136,GO:0044237,GO:0044249,GO:0044271,GO:0046209,GO:0055114,GO:0065007,GO:0065008,GO:0072593,GO:1903409,GO:2001057 1.14.14.47 ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 - R11711,R11712,R11713 RC00177,RC00330,RC01044 ko00000,ko00001,ko01000 - - - NO_synthase k141_18434_1 1453501.JELR01000001_gene2590 1.65e-43 152.0 COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,1S2IK@1236|Gammaproteobacteria,466ZA@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - - - - - - - - - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 k141_5343_1 1453501.JELR01000002_gene1496 5.74e-30 114.0 COG0330@1|root,COG0330@2|Bacteria,1MX2I@1224|Proteobacteria 1224|Proteobacteria O COG0330 Membrane protease subunits stomatin prohibitin homologs - - - - - - - - - - - - Band_7 k141_5343_2 1453501.JELR01000002_gene1495 7.04e-38 127.0 2EBER@1|root,335FA@2|Bacteria,1NDX3@1224|Proteobacteria,1SEUR@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - DUF350 k141_14704_3 314287.GB2207_00285 1.07e-51 166.0 COG3791@1|root,COG3791@2|Bacteria,1RH56@1224|Proteobacteria 1224|Proteobacteria S Glutathione-dependent formaldehyde-activating enzyme - - - - - - - - - - - - GFA k141_14704_4 1168067.JAGP01000001_gene1209 2.68e-122 354.0 COG2020@1|root,COG2020@2|Bacteria,1R7G6@1224|Proteobacteria,1S9RT@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Isoprenylcysteine carboxyl methyltransferase - - - - - - - - - - - - PEMT k141_2844_1 909613.UO65_5797 8.15e-16 82.4 COG1062@1|root,COG1062@2|Bacteria,2GM8C@201174|Actinobacteria,4DX4S@85010|Pseudonocardiales 201174|Actinobacteria C Zinc-binding dehydrogenase - - 1.1.1.1,1.1.1.284 ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 - R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N k141_2844_2 1089550.ATTH01000001_gene2109 1.54e-106 320.0 COG0492@1|root,COG0492@2|Bacteria,4NEVX@976|Bacteroidetes,1FIUF@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family trxB - 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Pyr_redox_2 k141_7586_1 1121472.AQWN01000001_gene30 4.66e-12 72.0 COG1074@1|root,COG1074@2|Bacteria,1TQ35@1239|Firmicutes,248ZF@186801|Clostridia,2606F@186807|Peptococcaceae 186801|Clostridia L ATP-dependent helicase nuclease subunit A addA - 3.6.4.12 ko:K16898 - - - - ko00000,ko01000,ko03400 - - - PDDEXK_1,UvrD-helicase,UvrD_C k141_1638_1 218284.CCDN010000006_gene3531 5.13e-57 187.0 COG0673@1|root,COG0673@2|Bacteria,1TR8S@1239|Firmicutes,4HBHI@91061|Bacilli,1ZDU7@1386|Bacillus 91061|Bacilli S Oxidoreductase yvaA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0070401,GO:0070402,GO:0097159,GO:0102497,GO:1901265,GO:1901363 1.1.1.371 ko:K16044 ko00562,ko01120,map00562,map01120 - R09954 RC00182 ko00000,ko00001,ko01000 - - - GFO_IDH_MocA,GFO_IDH_MocA_C k141_13745_1 218284.CCDN010000005_gene3470 2.14e-91 283.0 COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,4HC5M@91061|Bacilli,1ZB0M@1386|Bacillus 91061|Bacilli KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains rocR GO:0006082,GO:0006355,GO:0006520,GO:0006525,GO:0006807,GO:0008150,GO:0008152,GO:0009064,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031326,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1901564,GO:1901605,GO:1903506,GO:2000112,GO:2001141 - ko:K06714 - - - - ko00000,ko03000 - - - HTH_8,PAS,PAS_4,PAS_9,Sigma54_activat k141_19563_1 218284.CCDN010000001_gene646 1.11e-172 487.0 COG0510@1|root,COG0510@2|Bacteria,1VB8C@1239|Firmicutes,4HNC9@91061|Bacilli,1ZAQ0@1386|Bacillus 91061|Bacilli M choline kinase involved in LPS biosynthesis - - - - - - - - - - - - APH k141_26891_2 1121936.AUHI01000002_gene2662 7.68e-130 377.0 COG0385@1|root,COG0385@2|Bacteria,1TP85@1239|Firmicutes,4HBG6@91061|Bacilli 91061|Bacilli S Transporter - - - ko:K03453 - - - - ko00000 2.A.28 - - SBF k141_26891_3 1002809.SSIL_2408 1.35e-24 102.0 COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,4H9VR@91061|Bacilli,26DUZ@186818|Planococcaceae 91061|Bacilli E COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase - - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N k141_4150_1 765912.Thimo_2376 1.17e-55 185.0 COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,1RMWD@1236|Gammaproteobacteria,1WWK3@135613|Chromatiales 135613|Chromatiales S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation mltG - - ko:K07082 - - - - ko00000 - - - YceG k141_5344_1 218284.CCDN010000001_gene1753 1.52e-109 322.0 COG0180@1|root,COG0180@2|Bacteria,1TPY7@1239|Firmicutes,4HE96@91061|Bacilli,1ZE1U@1386|Bacillus 91061|Bacilli J Catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA - - 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1b k141_11285_1 42565.FP66_00795 1.08e-105 312.0 COG1638@1|root,COG1638@2|Bacteria,1MWAW@1224|Proteobacteria,1RZWY@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Bacterial extracellular solute-binding protein, family 7 - - - - - - - - - - - - DctP k141_20682_1 1397528.Q671_02035 2.6e-97 300.0 COG1178@1|root,COG1178@2|Bacteria,1MWCF@1224|Proteobacteria,1RNHK@1236|Gammaproteobacteria,1XI6E@135619|Oceanospirillales 135619|Oceanospirillales P thiamine ABC transporter - - - ko:K02063 ko02010,map02010 M00191 - - ko00000,ko00001,ko00002,ko02000 3.A.1.19 - - BPD_transp_1 k141_13746_1 218284.CCDN010000001_gene1386 1.86e-24 97.8 COG2176@1|root,COG2176@2|Bacteria,1V332@1239|Firmicutes,4HFP2@91061|Bacilli,1ZHN2@1386|Bacillus 91061|Bacilli L 3' exoribonuclease, RNase T-like - - 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - RNase_T k141_13746_2 218284.CCDN010000001_gene1387 3.33e-55 189.0 COG2905@1|root,COG2905@2|Bacteria,1TQFI@1239|Firmicutes,4HDTM@91061|Bacilli,1ZQQC@1386|Bacillus 91061|Bacilli T Putative nucleotidyltransferase substrate binding domain - - - ko:K07182 - - - - ko00000 - - - CBS,DUF294,DUF294_C,cNMP_binding k141_18436_1 1385513.N780_07055 1.6e-95 285.0 COG1624@1|root,COG1624@2|Bacteria,1TPRW@1239|Firmicutes,4H9XZ@91061|Bacilli,2YA5F@289201|Pontibacillus 91061|Bacilli S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria dacA GO:0003674,GO:0003824,GO:0004016,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0009975,GO:0016020,GO:0016021,GO:0016829,GO:0016849,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 2.7.7.85 ko:K18672 - - - - ko00000,ko01000 - - - DisA_N k141_26892_1 483219.LILAB_20390 1.55e-43 156.0 COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,42NA4@68525|delta/epsilon subdivisions,2WNXT@28221|Deltaproteobacteria,2YV4W@29|Myxococcales 28221|Deltaproteobacteria EGP of the major facilitator superfamily agmP - - - - - - - - - - - MFS_1,MFS_1_like,Sugar_tr k141_2845_1 1294265.JCM21738_1655 2.02e-114 335.0 COG0457@1|root,COG0457@2|Bacteria,1UBH2@1239|Firmicutes,4HB47@91061|Bacilli,1ZD40@1386|Bacillus 91061|Bacilli S COG0457 FOG TPR repeat yvcD - - - - - - - - - - - HTH_psq,TPR_16,TPR_19,TPR_2,TPR_8 k141_19564_1 1196031.ALEG01000003_gene3290 3.1e-94 288.0 COG2133@1|root,COG2133@2|Bacteria,1TSKS@1239|Firmicutes,4HDDU@91061|Bacilli,1ZE0F@1386|Bacillus 91061|Bacilli G Glucose / Sorbosone dehydrogenase - - - - - - - - - - - - GSDH k141_10132_1 1116375.VEJY3_03050 2.53e-131 406.0 COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,1RMRN@1236|Gammaproteobacteria,1XTXA@135623|Vibrionales 135623|Vibrionales F Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate purL GO:0003674,GO:0003824,GO:0004642,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - AIRS_C,GATase_5 k141_25573_1 218284.CCDN010000006_gene3741 8.34e-102 310.0 COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,4HA1G@91061|Bacilli,1ZASC@1386|Bacillus 91061|Bacilli G COG0366 Glycosidases dexB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.2.1.70 ko:K01215 - - - - ko00000,ko01000 - - - Alpha-amylase,DUF3459,Malt_amylase_C k141_14705_1 1042377.AFPJ01000010_gene1438 5.63e-09 55.8 COG1946@1|root,COG1946@2|Bacteria,1NAQM@1224|Proteobacteria,1RR0K@1236|Gammaproteobacteria,4645G@72275|Alteromonadaceae 1236|Gammaproteobacteria I acyl-CoA thioesterase - - 3.1.2.20 ko:K01073 - - - - ko00000,ko01000 - - - 4HBT_3 k141_14705_2 1453501.JELR01000001_gene3133 4.87e-132 381.0 COG0598@1|root,COG0598@2|Bacteria,1MW8W@1224|Proteobacteria,1RRTZ@1236|Gammaproteobacteria,464S0@72275|Alteromonadaceae 1236|Gammaproteobacteria P CorA-like Mg2+ transporter protein zntB GO:0000041,GO:0003674,GO:0005215,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0015562,GO:0016020,GO:0016021,GO:0022857,GO:0022883,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046583,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662 - ko:K16074 - - - - ko00000,ko02000 1.A.35.4 - - CorA k141_24253_1 1294265.JCM21738_2799 2.04e-38 130.0 COG3766@1|root,COG3766@2|Bacteria,1V6MT@1239|Firmicutes,4HH4E@91061|Bacilli,1ZG9Y@1386|Bacillus 91061|Bacilli S membrane yshE - - ko:K08989 - - - - ko00000 - - - DUF350 k141_24253_2 1294265.JCM21738_2798 4.73e-147 436.0 COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,4H9NZ@91061|Bacilli,1ZBJV@1386|Bacillus 91061|Bacilli L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity mutS2 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K07456 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_V,Smr k141_12586_1 1453501.JELR01000001_gene2940 1.62e-72 233.0 COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,1RMD2@1236|Gammaproteobacteria,46508@72275|Alteromonadaceae 1236|Gammaproteobacteria E Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate alkJ - 1.1.99.1 ko:K00108 ko00260,ko01100,map00260,map01100 M00555 R01025 RC00087 ko00000,ko00001,ko00002,ko01000 - - - GMC_oxred_C,GMC_oxred_N k141_5612_2 1487923.DP73_21855 8.76e-31 112.0 293T3@1|root,2ZR8H@2|Bacteria,1V593@1239|Firmicutes,24IBC@186801|Clostridia,26592@186807|Peptococcaceae 186801|Clostridia S Protein of unknown function (DUF2975) - - - - - - - - - - - - DUF2975 k141_2999_1 1415755.JQLV01000001_gene1171 2.29e-108 320.0 COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,1S070@1236|Gammaproteobacteria 1236|Gammaproteobacteria BQ COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein - - - - - - - - - - - - Hist_deacetyl k141_2999_2 1122139.KB907862_gene548 9.95e-27 105.0 COG0111@1|root,COG0111@2|Bacteria,1MW1U@1224|Proteobacteria,1RRQE@1236|Gammaproteobacteria,1XJI0@135619|Oceanospirillales 135619|Oceanospirillales EH D-isomer specific 2-hydroxyacid dehydrogenase - - 1.1.1.79,1.1.1.81 ko:K12972 ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00260,map00620,map00630,map01100,map01110,map01120 - R00465,R01388,R01392,R02527 RC00031,RC00042,RC00670 ko00000,ko00001,ko01000 - - - 2-Hacid_dh_C k141_1812_3 1453501.JELR01000002_gene1050 2.5e-159 448.0 28Q1W@1|root,2ZCK4@2|Bacteria,1RE1D@1224|Proteobacteria,1T19A@1236|Gammaproteobacteria,46D1X@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_7796_2 218284.CCDN010000010_gene4387 1.99e-54 175.0 COG1045@1|root,COG1045@2|Bacteria,1TR42@1239|Firmicutes,4HAKS@91061|Bacilli,1ZCNM@1386|Bacillus 91061|Bacilli E Serine acetyltransferase cysE GO:0000096,GO:0000097,GO:0000098,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009001,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009070,GO:0009087,GO:0009987,GO:0016053,GO:0016054,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.3.1.30 ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 M00021 R00586 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS02865,iYO844.BSU00930 Hexapep,SATase_N k141_19774_1 948106.AWZT01000001_gene5330 6.95e-13 70.5 COG0382@1|root,COG0382@2|Bacteria,1MXCM@1224|Proteobacteria,2VKY4@28216|Betaproteobacteria,1K0JV@119060|Burkholderiaceae 28216|Betaproteobacteria H PFAM UbiA prenyltransferase - - - - - - - - - - - - HAD,UbiA k141_19774_2 314265.R2601_05408 8.42e-17 77.8 COG2076@1|root,COG2076@2|Bacteria,1NAUF@1224|Proteobacteria 1224|Proteobacteria P of the drug metabolite transporter (DMT) superfamily - - - - - - - - - - - - EamA,Multi_Drug_Res k141_25840_1 1042377.AFPJ01000037_gene2900 5.76e-222 637.0 COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,1RMAP@1236|Gammaproteobacteria,464XP@72275|Alteromonadaceae 1236|Gammaproteobacteria M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamA GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - ko:K07277 - - - - ko00000,ko02000,ko03029 1.B.33 - - Bac_surface_Ag,POTRA k141_25840_2 1279017.AQYJ01000026_gene334 2.74e-51 169.0 COG2825@1|root,COG2825@2|Bacteria,1MZVJ@1224|Proteobacteria,1SA69@1236|Gammaproteobacteria,468H2@72275|Alteromonadaceae 1236|Gammaproteobacteria M Outer membrane protein (OmpH-like) ompH - - ko:K06142 - - - - ko00000 - - - OmpH k141_25840_3 1042377.AFPJ01000037_gene2898 1.19e-93 290.0 COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,1RNYI@1236|Gammaproteobacteria,4642M@72275|Alteromonadaceae 1236|Gammaproteobacteria M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxD GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 ko:K02536 ko00540,ko01100,map00540,map01100 M00060 R04550 RC00039,RC00166 ko00000,ko00001,ko00002,ko01000,ko01005 - - ic_1306.c0216 Hexapep,Hexapep_2,LpxD k141_25840_6 1279017.AQYJ01000026_gene330 5.72e-209 585.0 COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,1RNS1@1236|Gammaproteobacteria,465R6@72275|Alteromonadaceae 1236|Gammaproteobacteria M Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxB GO:0003674,GO:0003824,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008194,GO:0008289,GO:0008610,GO:0008654,GO:0008915,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0019637,GO:0019897,GO:0019898,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 ko:K00748 ko00540,ko01100,map00540,map01100 M00060 R04606 RC00005,RC00059 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT19 iE2348C_1286.E2348C_0187,iEcolC_1368.EcolC_3478 LpxB k141_25840_8 1453501.JELR01000001_gene1948 6.37e-245 679.0 COG4536@1|root,COG4536@2|Bacteria,1NZ99@1224|Proteobacteria,1RNCE@1236|Gammaproteobacteria,464AQ@72275|Alteromonadaceae 1236|Gammaproteobacteria P Mg2 and Co2 transporter CorB yfjD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - CBS,CorC_HlyC,DUF21 k141_25840_9 1279017.AQYJ01000026_gene327 2.19e-132 382.0 COG4137@1|root,COG4137@2|Bacteria,1R3YD@1224|Proteobacteria,1RPUQ@1236|Gammaproteobacteria,46700@72275|Alteromonadaceae 1236|Gammaproteobacteria S transport system, permease component ypjD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - Cytochrom_C_asm k141_25840_10 1042377.AFPJ01000037_gene2891 8.15e-196 552.0 COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,1RMU9@1236|Gammaproteobacteria,46456@72275|Alteromonadaceae 1236|Gammaproteobacteria U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components ffh GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006605,GO:0006612,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046907,GO:0048500,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1990904 3.6.5.4 ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko01000,ko02044 3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9 - - SRP54,SRP54_N,SRP_SPB k141_34043_1 796606.BMMGA3_15665 3.77e-20 84.0 COG3832@1|root,COG3832@2|Bacteria,1V587@1239|Firmicutes,4HJ9S@91061|Bacilli,1ZGJJ@1386|Bacillus 91061|Bacilli S Activator of Hsp90 ATPase homolog 1-like protein - - - - - - - - - - - - AHSA1 k141_34043_2 218284.CCDN010000002_gene2416 9.8e-58 184.0 2AYX9@1|root,31R2Z@2|Bacteria,1V1KP@1239|Firmicutes,4HFV5@91061|Bacilli,1ZFIN@1386|Bacillus 91061|Bacilli S DinB superfamily - - - - - - - - - - - - DinB_2 k141_9151_1 1294265.JCM21738_4896 7.5e-68 216.0 COG1972@1|root,COG1972@2|Bacteria,1TRSK@1239|Firmicutes,4HA8N@91061|Bacilli,1ZAW2@1386|Bacillus 91061|Bacilli F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family yutK GO:0003674,GO:0005215,GO:0005337,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0015858,GO:0015931,GO:0015932,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:1901264,GO:1901505,GO:1901642 - ko:K03317 - - - - ko00000 2.A.41 - iYO844.BSU32180 Gate,Nucleos_tra2_C,Nucleos_tra2_N k141_9151_2 1294265.JCM21738_4897 4.81e-125 361.0 COG2390@1|root,COG2390@2|Bacteria,1TPUB@1239|Firmicutes,4HCAR@91061|Bacilli,1ZD4S@1386|Bacillus 91061|Bacilli K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain deoR GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K05346 - - - - ko00000,ko03000 - - - HTH_23,HTH_24,HTH_Crp_2,MarR_2,Sigma70_r4,Sugar-bind k141_18740_1 861299.J421_3279 1.7e-75 238.0 COG0045@1|root,COG0045@2|Bacteria,1ZSZ4@142182|Gemmatimonadetes 142182|Gemmatimonadetes F Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit sucC - 6.2.1.5 ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp_2,Ligase_CoA k141_17325_1 935837.JAEK01000005_gene4330 3.83e-42 154.0 COG0770@1|root,COG0770@2|Bacteria,1UPUZ@1239|Firmicutes,4HTD6@91061|Bacilli,1ZQ3G@1386|Bacillus 91061|Bacilli M Mur ligase family, glutamate ligase domain - - 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 - R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase_C,Mur_ligase_M k141_17325_2 1121938.AUDY01000011_gene666 1.84e-52 179.0 COG0189@1|root,COG0189@2|Bacteria,1VE5B@1239|Firmicutes,4HCDJ@91061|Bacilli 91061|Bacilli HJ Endospore coat-associated protein yheC3 - - - - - - - - - - - ATPgrasp_YheCD k141_30274_1 218284.CCDN010000001_gene1641 2.11e-95 283.0 COG1388@1|root,COG1388@2|Bacteria,1V5F7@1239|Firmicutes,4HH73@91061|Bacilli,1ZGCI@1386|Bacillus 91061|Bacilli M LysM domain - - - - - - - - - - - - - k141_16166_1 218284.CCDN010000001_gene1208 1.01e-08 57.0 COG1162@1|root,COG1162@2|Bacteria,1TP8Q@1239|Firmicutes,4H9PJ@91061|Bacilli,1ZCAI@1386|Bacillus 91061|Bacilli S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit rsgA_2 - 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 - R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 - - - RsgA_GTPase k141_25841_1 1267534.KB906756_gene109 3.91e-15 80.5 COG0823@1|root,COG3710@1|root,COG0823@2|Bacteria,COG3710@2|Bacteria 2|Bacteria K Transcriptional regulator - - 4.6.1.13 ko:K01771 ko00562,map00562 - R03332 RC00017,RC00425 ko00000,ko00001,ko01000 - - - PD40,PI-PLC-X,Trans_reg_C k141_23455_1 1116375.VEJY3_05925 2.51e-184 535.0 COG0577@1|root,COG0577@2|Bacteria,1MVCT@1224|Proteobacteria,1RNP1@1236|Gammaproteobacteria,1XUDJ@135623|Vibrionales 135623|Vibrionales V ABC-type antimicrobial peptide transport system, permease component - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD k141_23455_2 1116375.VEJY3_05920 4.85e-156 438.0 COG1136@1|root,COG1136@2|Bacteria,1NCFC@1224|Proteobacteria,1S18G@1236|Gammaproteobacteria,1XTFP@135623|Vibrionales 135623|Vibrionales V ABC-type antimicrobial peptide transport system, ATPase component - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_23455_3 1116375.VEJY3_05915 2.16e-300 823.0 COG0534@1|root,COG0534@2|Bacteria,1QTIW@1224|Proteobacteria,1RZ7Q@1236|Gammaproteobacteria,1XSUZ@135623|Vibrionales 135623|Vibrionales V Na driven multidrug efflux pump vcmH - - - - - - - - - - - MatE k141_23455_4 1116375.VEJY3_05910 0.0 885.0 COG0702@1|root,COG0702@2|Bacteria,1MW54@1224|Proteobacteria,1RNS7@1236|Gammaproteobacteria,1XTP2@135623|Vibrionales 135623|Vibrionales GM nucleoside-diphosphate-sugar epimerases ybjT - - - - - - - - - - - DUF2867,Epimerase,NAD_binding_10 k141_23455_5 1116375.VEJY3_05905 8.08e-112 323.0 COG3005@1|root,COG3005@2|Bacteria,1RKR7@1224|Proteobacteria,1S6B2@1236|Gammaproteobacteria,1XX99@135623|Vibrionales 135623|Vibrionales C NapC/NirT cytochrome c family, N-terminal region - - - - - - - - - - - - Cytochrom_NNT k141_23455_6 1116375.VEJY3_05900 9.28e-128 365.0 COG2863@1|root,COG2863@2|Bacteria,1R8K9@1224|Proteobacteria,1S1Q4@1236|Gammaproteobacteria,1XX4A@135623|Vibrionales 135623|Vibrionales C Cytochrome C oxidase, cbb3-type, subunit III - - - ko:K17230 ko00920,ko01120,map00920,map01120 - R09499 - ko00000,ko00001 - - - Cytochrome_CBB3 k141_23455_7 1116375.VEJY3_05895 0.0 1475.0 2DBW6@1|root,2ZBEP@2|Bacteria,1QUH5@1224|Proteobacteria,1RY0G@1236|Gammaproteobacteria,1XWKU@135623|Vibrionales 135623|Vibrionales C TIGRFAM decaheme c-type cytochrome, OmcA MtrC family - - - - - - - - - - - - Cytochrome_C7 k141_23455_8 1116375.VEJY3_05890 2.2e-225 622.0 COG3005@1|root,COG3005@2|Bacteria,1R4UP@1224|Proteobacteria,1RZUI@1236|Gammaproteobacteria,1XVBV@135623|Vibrionales 135623|Vibrionales C Cytochrome c7 and related cytochrome c - - - - - - - - - - - - Paired_CXXCH_1 k141_23455_9 1116375.VEJY3_05885 0.0 1097.0 COG2067@1|root,COG2067@2|Bacteria,1QUH6@1224|Proteobacteria,1T1YR@1236|Gammaproteobacteria,1XWSI@135623|Vibrionales 135623|Vibrionales I Putative outer membrane beta-barrel porin, MtrB/PioB - - - - - - - - - - - - MtrB_PioB k141_23455_10 223926.28806205 1.81e-146 414.0 2EAF8@1|root,334IN@2|Bacteria,1ND4K@1224|Proteobacteria,1SBS5@1236|Gammaproteobacteria,1XTF7@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF2913) VP1217 - - - - - - - - - - - DUF2913 k141_23455_11 1116375.VEJY3_05875 3.03e-261 719.0 COG0477@1|root,COG2814@2|Bacteria,1MW19@1224|Proteobacteria,1RMSZ@1236|Gammaproteobacteria,1XSKM@135623|Vibrionales 135623|Vibrionales EGP of the major facilitator superfamily bcr - - ko:K07552 - - - - ko00000,ko02000 2.A.1.2 - - MFS_1 k141_22123_1 1122137.AQXF01000007_gene3602 0.0 1163.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MV8W@1224|Proteobacteria,2TUDX@28211|Alphaproteobacteria 28211|Alphaproteobacteria P receptor - - - - - - - - - - - - Plug,TonB_dep_Rec k141_20853_1 42565.FP66_12250 5.2e-126 392.0 COG0457@1|root,COG3629@1|root,COG3899@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,1S0DF@1236|Gammaproteobacteria,1XJFP@135619|Oceanospirillales 135619|Oceanospirillales K AAA ATPase domain - - - - - - - - - - - - AAA_16 k141_27899_1 218284.CCDN010000002_gene2819 1.61e-102 307.0 COG0577@1|root,COG0577@2|Bacteria,1TWFZ@1239|Firmicutes,4H9RQ@91061|Bacilli,1ZCYR@1386|Bacillus 91061|Bacilli V FtsX-like permease family hrtB GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02004,ko:K09813 ko02010,map02010 M00257,M00258 - - ko00000,ko00001,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD k141_14049_1 1169144.KB910935_gene2053 2.34e-139 412.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1TR2N@1239|Firmicutes,4H9RR@91061|Bacilli,1ZB2Q@1386|Bacillus 91061|Bacilli EU peptidase yuxL - 3.4.19.1 ko:K01303 - - - - ko00000,ko01000,ko01002 - - - PD40,Peptidase_S9 k141_24539_1 1279017.AQYJ01000027_gene1653 8.18e-215 602.0 COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,1RMQU@1236|Gammaproteobacteria,4662Y@72275|Alteromonadaceae 1236|Gammaproteobacteria H COG0303 Molybdopterin biosynthesis enzyme moeA - 2.10.1.1 ko:K03750 ko00790,ko01100,map00790,map01100 - R09735 RC03462 ko00000,ko00001,ko01000 - - - MoCF_biosynth,MoeA_C,MoeA_N k141_24539_2 1279017.AQYJ01000027_gene1654 2.38e-116 337.0 COG2197@1|root,COG2197@2|Bacteria,1NQH7@1224|Proteobacteria,1RNXI@1236|Gammaproteobacteria,465FY@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain narL - - ko:K07684 ko02020,map02020 M00471 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg k141_18741_1 666686.B1NLA3E_13535 9.51e-59 184.0 COG3794@1|root,COG3794@2|Bacteria,1VQGS@1239|Firmicutes,4HXFN@91061|Bacilli,1ZH4H@1386|Bacillus 91061|Bacilli C Copper binding proteins, plastocyanin/azurin family - - - - - - - - - - - - Cupredoxin_1 k141_1814_1 1004785.AMBLS11_13575 7.95e-124 367.0 COG5434@1|root,COG5434@2|Bacteria,1MXP8@1224|Proteobacteria,1RRJZ@1236|Gammaproteobacteria,4644J@72275|Alteromonadaceae 1236|Gammaproteobacteria G Belongs to the glycosyl hydrolase 28 family - - - - - - - - - - - - Glyco_hydro_28 k141_4285_1 1196031.ALEG01000039_gene1023 2.29e-104 315.0 COG0388@1|root,COG0454@1|root,COG0388@2|Bacteria,COG0456@2|Bacteria,1TQAZ@1239|Firmicutes,4HCQW@91061|Bacilli,1ZB16@1386|Bacillus 91061|Bacilli K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase yhcX - - - - - - - - - - - Acetyltransf_1,CN_hydrolase k141_858_1 218284.CCDN010000008_gene4185 5.08e-193 555.0 COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,4HAG1@91061|Bacilli,1ZARG@1386|Bacillus 91061|Bacilli J Belongs to the class-I aminoacyl-tRNA synthetase family leuS GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Anticodon_1,tRNA-synt_1,tRNA-synt_1_2 k141_24540_1 1385511.N783_21630 3.43e-83 261.0 COG0388@1|root,COG0454@1|root,COG0388@2|Bacteria,COG0456@2|Bacteria,1TQAZ@1239|Firmicutes,4HCQW@91061|Bacilli,2Y8X8@289201|Pontibacillus 91061|Bacilli K Hydrolase yhcX - - - - - - - - - - - Acetyltransf_1,CN_hydrolase k141_37463_1 1121937.AUHJ01000001_gene691 7.1e-86 261.0 COG1540@1|root,COG1540@2|Bacteria,1MUYV@1224|Proteobacteria,1RSCZ@1236|Gammaproteobacteria,4659M@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the UPF0271 (lamB) family lamB - - ko:K07160 - - - - ko00000 - - - LamB_YcsF k141_37463_2 1487921.DP68_04345 1.61e-37 140.0 COG1984@1|root,COG1984@2|Bacteria,1TR6U@1239|Firmicutes,2485K@186801|Clostridia,36E0F@31979|Clostridiaceae 186801|Clostridia E Allophanate hydrolase subunit 2 kipA - - ko:K06350 - - - - ko00000 - - - CT_A_B k141_25843_1 218284.CCDN010000007_gene3786 5.39e-37 140.0 COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,4HAHY@91061|Bacilli,1ZB8F@1386|Bacillus 91061|Bacilli L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrA - 5.99.1.3 ko:K02469 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseA_C,DNA_topoisoIV k141_9153_1 1279017.AQYJ01000019_gene1513 1.4e-168 484.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,4642R@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains pilR - - ko:K02481,ko:K02667 ko02020,map02020 M00501 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - HTH_8,Response_reg,Sigma54_activat k141_22125_1 1121938.AUDY01000013_gene3171 4.92e-56 179.0 COG0450@1|root,COG0450@2|Bacteria,1TQU7@1239|Firmicutes,4HAR6@91061|Bacilli,3NE5B@45667|Halobacillus 91061|Bacilli O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides - - 1.11.1.15 ko:K03386 ko04214,map04214 - - - ko00000,ko00001,ko01000,ko04147 - - - 1-cysPrx_C,AhpC-TSA k141_19778_1 671143.DAMO_0704 4.54e-55 184.0 COG0404@1|root,COG0404@2|Bacteria,2NNSR@2323|unclassified Bacteria 2|Bacteria E The glycine cleavage system catalyzes the degradation of glycine gcvT - 2.1.2.10 ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 M00532 R01221,R02300,R04125 RC00022,RC00069,RC00183,RC02834 ko00000,ko00001,ko00002,ko01000 - - - GCV_T,GCV_T_C k141_36238_2 1279017.AQYJ01000025_gene720 5.21e-170 478.0 28Q06@1|root,2ZCJ3@2|Bacteria,1RC3X@1224|Proteobacteria,1S0S9@1236|Gammaproteobacteria,469IG@72275|Alteromonadaceae 1236|Gammaproteobacteria S Predicted membrane protein (DUF2306) - - - - - - - - - - - - DUF2306 k141_36238_3 1279017.AQYJ01000025_gene718 1.28e-194 551.0 COG4585@1|root,COG4585@2|Bacteria,1R6FX@1224|Proteobacteria,1S0UD@1236|Gammaproteobacteria,467NI@72275|Alteromonadaceae 1236|Gammaproteobacteria T Histidine kinase desK - 2.7.13.3 ko:K07778 ko02020,map02020 M00479 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA_3 k141_24541_1 218284.CCDN010000005_gene3361 8.88e-110 329.0 COG0168@1|root,COG0168@2|Bacteria,1TQ4S@1239|Firmicutes,4H9ME@91061|Bacilli,1ZD2H@1386|Bacillus 91061|Bacilli P COG0168 Trk-type K transport systems, membrane components ktrD - - - - - - - - - - - TrkH k141_30276_1 1404245.CGLY_15120 4.8e-25 105.0 COG0451@1|root,COG0451@2|Bacteria,2GNH5@201174|Actinobacteria 201174|Actinobacteria GM NAD-dependent epimerase dehydratase - - - - - - - - - - - - Epimerase k141_7800_1 42099.EPrPV00000017648 2.01e-52 186.0 COG1024@1|root,KOG1683@2759|Eukaryota,1MEES@121069|Pythiales 121069|Pythiales I Trifunctional enzyme subunit alpha. Source PGD - - - - - - - - - - - - 3HCDH,3HCDH_N,ECH_1 k141_22126_1 981383.AEWH01000051_gene448 1.32e-19 87.4 COG4177@1|root,COG4177@2|Bacteria,1TPMZ@1239|Firmicutes,4HBB8@91061|Bacilli 91061|Bacilli E Belongs to the binding-protein-dependent transport system permease family - - - ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 k141_27901_1 218284.CCDN010000001_gene787 2.58e-87 277.0 COG0768@1|root,COG0768@2|Bacteria,1TQHY@1239|Firmicutes,4HAFX@91061|Bacilli,1ZBJM@1386|Bacillus 91061|Bacilli M penicillin-binding protein pbpH - - ko:K21465 ko00550,map00550 - - - ko00000,ko00001,ko01011 - - - PBP_dimer,Transpeptidase k141_9154_1 1443665.JACA01000005_gene389 1.05e-46 167.0 arCOG10304@1|root,30WUR@2|Bacteria,4NGAA@976|Bacteroidetes,1HZC7@117743|Flavobacteriia,2YGWM@290174|Aquimarina 976|Bacteroidetes - - - - - - - - - - - - - - - k141_34045_1 218284.CCDN010000001_gene1005 1.48e-208 580.0 COG1902@1|root,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,4HA6I@91061|Bacilli,1ZQ99@1386|Bacillus 91061|Bacilli C NADH:flavin oxidoreductase / NADH oxidase family - - - - - - - - - - - - Oxidored_FMN k141_17327_1 1077974.GOEFS_067_00120 1.55e-31 117.0 COG4922@1|root,COG4922@2|Bacteria,2GUR3@201174|Actinobacteria,4GEJF@85026|Gordoniaceae 201174|Actinobacteria S SnoaL-like polyketide cyclase - - - - - - - - - - - - SnoaL,SnoaL_2 k141_17327_2 1286106.MPL1_02443 9.24e-23 90.1 COG3865@1|root,COG3865@2|Bacteria,1MZHY@1224|Proteobacteria,1S520@1236|Gammaproteobacteria 1236|Gammaproteobacteria S 3-demethylubiquinone-9 3-methyltransferase - - - - - - - - - - - - 3-dmu-9_3-mt k141_25845_2 351016.RAZWK3B_12544 3.69e-35 133.0 COG0004@1|root,COG0004@2|Bacteria,1MX44@1224|Proteobacteria,2TR55@28211|Alphaproteobacteria,2P4FE@2433|Roseobacter 28211|Alphaproteobacteria P COG0004 Ammonia permease amt - - - - - - - - - - - Ammonium_transp k141_14951_2 1123236.KB899381_gene2952 6.23e-56 192.0 COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,1RMWZ@1236|Gammaproteobacteria,465GZ@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain alaS GO:0001130,GO:0001131,GO:0001141,GO:0001217,GO:0002161,GO:0002196,GO:0003674,GO:0003700,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006355,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009451,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019219,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0052689,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:0140110,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iECABU_c1320.ECABU_c29670,iECED1_1282.ECED1_3146,iEcHS_1320.EcHS_A2833,iJN746.PP_4474 DHHA1,tRNA-synt_2c,tRNA_SAD k141_6756_1 218284.CCDN010000001_gene120 3.24e-31 112.0 COG2905@1|root,COG2905@2|Bacteria,1VW3X@1239|Firmicutes,4HJ81@91061|Bacilli,1ZH6S@1386|Bacillus 91061|Bacilli T COG0517 FOG CBS domain ylbB - - - - - - - - - - - CBS k141_6756_2 218284.CCDN010000001_gene121 1.17e-46 151.0 2AHI2@1|root,317VK@2|Bacteria,1V6HY@1239|Firmicutes,4HJHD@91061|Bacilli,1ZHCP@1386|Bacillus 91061|Bacilli S YugN-like family ylbA - - - - - - - - - - - YugN k141_14083_1 1379270.AUXF01000002_gene1557 1.46e-43 161.0 COG2091@1|root,COG2091@2|Bacteria,1ZUQA@142182|Gemmatimonadetes 142182|Gemmatimonadetes H lysine biosynthetic process via aminoadipic acid - - - - - - - - - - - - - k141_31439_1 1196031.ALEG01000054_gene5539 9.97e-20 87.4 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli,1ZAXK@1386|Bacillus 91061|Bacilli C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively - - - ko:K22187 ko00040,map00040 - R11768 RC00080 ko00000,ko00001,ko01000 - - - Aldedh k141_31439_2 1340434.AXVA01000008_gene3641 3.16e-86 256.0 COG3193@1|root,COG3193@2|Bacteria,1V5C7@1239|Firmicutes,4HHN9@91061|Bacilli,1ZDSC@1386|Bacillus 91061|Bacilli S protein, possibly involved in utilization of glycolate and propanediol - - - - - - - - - - - - Haem_degrading k141_31439_3 1196031.ALEG01000054_gene5537 1.71e-50 164.0 COG2059@1|root,COG2059@2|Bacteria,1V43H@1239|Firmicutes,4HFWH@91061|Bacilli,1ZFJR@1386|Bacillus 91061|Bacilli P COG2059 Chromate transport protein ChrA ywrB - - ko:K07240 - - - - ko00000,ko02000 2.A.51.1 - - Chromate_transp k141_19811_1 218284.CCDN010000001_gene39 6.59e-74 225.0 COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,4H9RW@91061|Bacilli,1ZCUF@1386|Bacillus 91061|Bacilli G Belongs to the ribulose-phosphate 3-epimerase family rpe GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 - - - Ribul_P_3_epim k141_7827_1 502025.Hoch_1100 2.65e-27 115.0 COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42PPB@68525|delta/epsilon subdivisions,2X5YN@28221|Deltaproteobacteria,2YUEJ@29|Myxococcales 28221|Deltaproteobacteria KLT serine threonine protein kinase - - 2.7.11.1 ko:K08884,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - Pkinase,TPR_10,TPR_12 k141_22156_1 1453501.JELR01000001_gene3252 2.54e-65 217.0 COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,1SC2U@1236|Gammaproteobacteria,46A5A@72275|Alteromonadaceae 1236|Gammaproteobacteria T diguanylate cyclase ycdT GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0032879,GO:0042710,GO:0044010,GO:0044464,GO:0044764,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051270,GO:0051271,GO:0051704,GO:0052621,GO:0065007,GO:0071944,GO:0090605,GO:0090609 - - - - - - - - - - 7TMR-DISMED2,7TMR-DISM_7TM,GGDEF,MASE4 k141_5655_1 1297742.A176_00181 4.17e-27 114.0 COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,42ND6@68525|delta/epsilon subdivisions,2WIJS@28221|Deltaproteobacteria,2YURF@29|Myxococcales 28221|Deltaproteobacteria H Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration nnrD - 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 - - - - ko00000,ko01000 - - - Carb_kinase,YjeF_N k141_34061_2 1279017.AQYJ01000027_gene1621 9.53e-226 625.0 COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,1RN0B@1236|Gammaproteobacteria,464NP@72275|Alteromonadaceae 1236|Gammaproteobacteria NU COG5008 Tfp pilus assembly protein, ATPase PilU pilU - - ko:K02670 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE k141_24569_1 218284.CCDN010000001_gene1344 2.36e-120 353.0 COG3853@1|root,COG3853@2|Bacteria,1TQVX@1239|Firmicutes,4H9Z6@91061|Bacilli,1ZATR@1386|Bacillus 91061|Bacilli P Belongs to the TelA family yaaN - - - - - - - - - - - TelA k141_17341_1 218284.CCDN010000001_gene942 3.48e-144 417.0 COG1003@1|root,COG1003@2|Bacteria,1TPK9@1239|Firmicutes,4HB80@91061|Bacilli,1ZATI@1386|Bacillus 91061|Bacilli E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor gcvPB - 1.4.4.2 ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 - R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko01000 - - - GDC-P k141_36253_1 1535287.JP74_18265 1.2e-45 161.0 COG0520@1|root,COG0520@2|Bacteria,1MXH1@1224|Proteobacteria,2TQUT@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Selenocysteine lyase - - - - - - - - - - - - Aminotran_5 k141_19812_1 493475.GARC_4941 1.55e-48 171.0 COG0642@1|root,COG0642@2|Bacteria,1QTSX@1224|Proteobacteria,1T1G3@1236|Gammaproteobacteria,46D9B@72275|Alteromonadaceae 1236|Gammaproteobacteria T His Kinase A (phosphoacceptor) domain qseC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 ko:K07645 ko02020,ko02024,map02020,map02024 M00453 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - 2CSK_N,HATPase_c,HisKA k141_23493_1 1196322.A370_02096 1.78e-11 59.3 28WBB@1|root,2ZIBS@2|Bacteria,1W55H@1239|Firmicutes,255A0@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k141_24570_1 1042377.AFPJ01000054_gene1695 3.59e-88 263.0 2C5U9@1|root,2Z9NJ@2|Bacteria,1R6D0@1224|Proteobacteria,1SAQZ@1236|Gammaproteobacteria,46861@72275|Alteromonadaceae 1236|Gammaproteobacteria S Bacterial protein of unknown function (Gcw_chp) - - - - - - - - - - - - Gcw_chp k141_29457_1 1280001.BAOA01000021_gene716 6.11e-216 622.0 COG1596@1|root,COG1596@2|Bacteria,1N7GP@1224|Proteobacteria,1RQSM@1236|Gammaproteobacteria,1XUWY@135623|Vibrionales 135623|Vibrionales M Periplasmic protein involved in polysaccharide export - - - - - - - - - - - - Poly_export,SLBB k141_24763_1 218284.CCDN010000001_gene1413 2.55e-50 160.0 COG0607@1|root,COG0607@2|Bacteria,1VES3@1239|Firmicutes,4HNRE@91061|Bacilli,1ZI0X@1386|Bacillus 91061|Bacilli P Rhodanese domain protein - - - - - - - - - - - - Rhodanese k141_7085_1 218284.CCDN010000002_gene2054 8.46e-188 536.0 COG0668@1|root,COG0668@2|Bacteria,1TQXJ@1239|Firmicutes,4HCK2@91061|Bacilli,1ZF3F@1386|Bacillus 91061|Bacilli M Conserved TM helix ygxB - - - - - - - - - - - TM_helix k141_7085_2 1196031.ALEG01000006_gene473 1.05e-94 300.0 COG1948@1|root,COG4880@2|Bacteria,1TQK0@1239|Firmicutes,4H9YF@91061|Bacilli,1ZDVB@1386|Bacillus 91061|Bacilli L Beta propeller domain - - - - - - - - - - - - Beta_propel,Big_5,Cu_amine_oxidN1 k141_35540_1 1283337.B0ZSF6_BPHA1 1.31e-41 142.0 4QFG8@10239|Viruses,4QW2I@35237|dsDNA viruses no RNA stage,4QTVN@28883|Caudovirales,4QJ2K@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k141_35540_2 1283337.B0ZSF7_BPHA1 1.03e-34 124.0 4QC8P@10239|Viruses,4QVGB@35237|dsDNA viruses no RNA stage,4QQU4@28883|Caudovirales,4QI43@10662|Myoviridae 10662|Myoviridae S Phage-related baseplate assembly protein - - - - - - - - - - - - - k141_1996_1 218284.CCDN010000002_gene2229 7.18e-162 476.0 COG5000@1|root,COG5002@1|root,COG5000@2|Bacteria,COG5002@2|Bacteria,1VS6X@1239|Firmicutes,4HV7W@91061|Bacilli,1ZS6R@1386|Bacillus 91061|Bacilli T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,dCache_1 k141_32980_1 796606.BMMGA3_16110 9.8e-185 517.0 COG1494@1|root,COG1494@2|Bacteria,1TP0D@1239|Firmicutes,4H9MV@91061|Bacilli,1ZC28@1386|Bacillus 91061|Bacilli G fructose-1,6-bisphosphatase glpX GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030388,GO:0042132,GO:0042578,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0050308,GO:0071704,GO:1901135,GO:1901576 3.1.3.11 ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 M00003,M00165,M00167 R00762,R04780 RC00017 ko00000,ko00001,ko00002,ko01000 - - - FBPase_glpX k141_7086_1 1453501.JELR01000002_gene1522 3.95e-129 383.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,464Y3@72275|Alteromonadaceae 1236|Gammaproteobacteria T GGDEF domain - - - - - - - - - - - - 7TMR-DISMED2,EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9 k141_17434_1 1116375.VEJY3_05765 5.58e-307 841.0 COG0733@1|root,COG0733@2|Bacteria,1MUZJ@1224|Proteobacteria,1RPCT@1236|Gammaproteobacteria,1XT5X@135623|Vibrionales 135623|Vibrionales S COG0733 Na -dependent transporters of the SNF family - - - ko:K03308 - - - - ko00000 2.A.22.4,2.A.22.5 - - SNF k141_17434_2 1280001.BAOA01000078_gene3144 2.61e-252 707.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RPWV@1236|Gammaproteobacteria,1XUDV@135623|Vibrionales 135623|Vibrionales NT methyl-accepting chemotaxis protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal k141_17434_3 1219076.N646_0233 5.22e-157 441.0 COG0564@1|root,COG0564@2|Bacteria,1RDAG@1224|Proteobacteria,1S406@1236|Gammaproteobacteria,1XVCV@135623|Vibrionales 135623|Vibrionales J COG0564 Pseudouridylate synthases, 23S RNA-specific - - 5.4.99.28,5.4.99.29 ko:K06177 - - - - ko00000,ko01000,ko03009,ko03016 - - - PseudoU_synth_2 k141_17434_4 223926.28806175 5.35e-217 599.0 COG1092@1|root,COG1092@2|Bacteria,1PUHQ@1224|Proteobacteria,1RN8N@1236|Gammaproteobacteria,1XTCF@135623|Vibrionales 135623|Vibrionales J Belongs to the methyltransferase superfamily - - 2.1.1.191 ko:K06969 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_SAM k141_17434_5 1280001.BAOA01000078_gene3141 2.84e-210 585.0 COG1018@1|root,COG1018@2|Bacteria,1MY2Q@1224|Proteobacteria,1RR5A@1236|Gammaproteobacteria,1XSSA@135623|Vibrionales 135623|Vibrionales C COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 gbcB - - ko:K11933 - - - - ko00000,ko01000 - - - FAD_binding_6,Fer2,NAD_binding_1 k141_24776_1 223926.28809414 2.15e-242 672.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,1XSW9@135623|Vibrionales 135623|Vibrionales C Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid betB - 1.2.1.8 ko:K00130 ko00260,ko01100,map00260,map01100 M00555 R02565,R02566 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_7131_1 1279017.AQYJ01000024_gene1003 1.1e-70 225.0 COG0730@1|root,COG0730@2|Bacteria,1QRFH@1224|Proteobacteria,1RRFY@1236|Gammaproteobacteria,465YS@72275|Alteromonadaceae 1236|Gammaproteobacteria S Sulfite exporter TauE/SafE - - - - - - - - - - - - TauE k141_1123_1 1411685.U062_00446 4.93e-34 132.0 COG3639@1|root,COG3639@2|Bacteria,1N3HU@1224|Proteobacteria,1RYH5@1236|Gammaproteobacteria,1J7WT@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P COG3639 ABC-type phosphate phosphonate transport system, permease component phnE - - ko:K02042 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - BPD_transp_1 k141_21038_1 218284.CCDN010000002_gene2030 1.86e-178 506.0 COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,4HA6M@91061|Bacilli,1ZB9G@1386|Bacillus 91061|Bacilli J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family rlmCD GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070041,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.190 ko:K03215 - - - - ko00000,ko01000,ko03009 - - - TRAM,tRNA_U5-meth_tr k141_26109_1 218284.CCDN010000008_gene4176 4.6e-89 264.0 COG0275@1|root,COG0275@2|Bacteria,1UHPG@1239|Firmicutes,4IS5B@91061|Bacilli,1ZFKV@1386|Bacillus 91061|Bacilli M Putative rRNA methylase ytqB - - - - - - - - - - - rRNA_methylase k141_10506_1 218284.CCDN010000007_gene3824 8.1e-85 263.0 COG0739@1|root,COG0739@2|Bacteria,1TRWJ@1239|Firmicutes,4HB43@91061|Bacilli,1ZBXH@1386|Bacillus 91061|Bacilli M G5 nlpD - - - - - - - - - - - G5,LysM,Peptidase_M23 k141_31587_2 1453501.JELR01000001_gene2636 4.3e-176 502.0 COG3768@1|root,COG3768@2|Bacteria,1MU8S@1224|Proteobacteria,1RND9@1236|Gammaproteobacteria,467RT@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF697) ycjF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K08990 - - - - ko00000 - - - DUF697 k141_31587_3 46429.BV95_02676 1.03e-21 91.7 COG3832@1|root,COG3832@2|Bacteria,1RH7Z@1224|Proteobacteria,2U9E1@28211|Alphaproteobacteria,2K54H@204457|Sphingomonadales 204457|Sphingomonadales J glyoxalase III activity - - - - - - - - - - - - AHSA1,Polyketide_cyc2 k141_16413_2 218284.CCDN010000001_gene1763 5.4e-64 200.0 COG4767@1|root,COG4767@2|Bacteria,1VIHV@1239|Firmicutes,4HPUJ@91061|Bacilli 91061|Bacilli V VanZ like family - - - - - - - - - - - - VanZ k141_4476_1 1294265.JCM21738_4529 1.92e-119 350.0 COG3263@1|root,COG3263@2|Bacteria,1TQPJ@1239|Firmicutes,4HC8I@91061|Bacilli,1ZC6H@1386|Bacillus 91061|Bacilli P COG3263 NhaP-type Na H and K H antiporters with a unique C-terminal domain nhaP - - ko:K11105 - - - - ko00000,ko02000 2.A.36.6 - - Na_H_Exchanger,TrkA_C k141_4476_2 1294265.JCM21738_4528 1.83e-77 234.0 COG1309@1|root,COG1309@2|Bacteria,1VDNV@1239|Firmicutes,4HKG8@91061|Bacilli,1ZI66@1386|Bacillus 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - TetR_C_6,TetR_N k141_12997_1 1279017.AQYJ01000023_gene3171 7.12e-47 155.0 COG0377@1|root,COG0377@2|Bacteria,1MUI2@1224|Proteobacteria,1RP4R@1236|Gammaproteobacteria,469EA@72275|Alteromonadaceae 1236|Gammaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoB - 1.6.5.3 ko:K00331 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q6 k141_12997_2 1279017.AQYJ01000023_gene3170 4.16e-268 748.0 COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,1RM98@1236|Gammaproteobacteria,465ZI@72275|Alteromonadaceae 1236|Gammaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoC GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 ko:K13378 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - iECDH10B_1368.ECDH10B_2448,iECDH1ME8569_1439.ECDH1ME8569_2223,iETEC_1333.ETEC_2421,iEcDH1_1363.EcDH1_1371,iPC815.YPO2553,iUMNK88_1353.UMNK88_2836 Complex1_30kDa,Complex1_49kDa k141_20090_1 1178540.BA70_19745 1.09e-151 433.0 COG0343@1|root,COG0343@2|Bacteria,1TNZ4@1239|Firmicutes,4HCNM@91061|Bacilli,1ZBFJ@1386|Bacillus 91061|Bacilli F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) tgt GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 ko:K00773 - - R03789,R10209 RC00063 ko00000,ko01000,ko03016 - - - TGT k141_17487_1 1121405.dsmv_0585 3.56e-49 177.0 COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions,2WJ4J@28221|Deltaproteobacteria,2MHN2@213118|Desulfobacterales 28221|Deltaproteobacteria P ATPase, P-type (transporting), HAD superfamily, subfamily IC - - 3.6.3.54 ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - - E1-E2_ATPase,HMA,Hydrolase k141_7133_1 1121938.AUDY01000011_gene601 1.32e-109 329.0 COG2132@1|root,COG2132@2|Bacteria,1TQSU@1239|Firmicutes,4HDD6@91061|Bacilli 91061|Bacilli Q Multicopper cotA GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016679,GO:0016682,GO:0016722,GO:0052716,GO:0055114 1.16.3.3 ko:K06324 - - - - ko00000,ko01000 - - - Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3 k141_3280_2 218284.CCDN010000001_gene548 7.81e-36 122.0 2E3SP@1|root,32YQ7@2|Bacteria,1VFJP@1239|Firmicutes,4HNJI@91061|Bacilli,1ZIXT@1386|Bacillus 91061|Bacilli S Belongs to the SspI family sspI - - ko:K06426 - - - - ko00000 - - - SSPI k141_3280_3 218284.CCDN010000001_gene547 1.22e-18 81.3 COG1335@1|root,COG1335@2|Bacteria,1V2DX@1239|Firmicutes,4HJMV@91061|Bacilli,1ZGBB@1386|Bacillus 91061|Bacilli Q Isochorismatase family - - - - - - - - - - - - Isochorismatase k141_29484_1 1191523.MROS_0965 5.3e-17 86.3 COG1629@1|root,COG4771@2|Bacteria 2|Bacteria P TonB-dependent receptor - - - - - - - - - - - - CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec k141_31588_1 218284.CCDN010000008_gene4214 1.26e-78 259.0 COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,4HA1S@91061|Bacilli,1ZAYY@1386|Bacillus 91061|Bacilli D Belongs to the FtsK SpoIIIE SftA family sftA - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_SpoIIIE,Ftsk_gamma k141_4477_1 1294265.JCM21738_2145 5.99e-96 287.0 2BZRV@1|root,2Z8AV@2|Bacteria,1UX40@1239|Firmicutes,4HAVP@91061|Bacilli,1ZDM4@1386|Bacillus 91061|Bacilli S Nuclease-related domain - - - - - - - - - - - - NERD k141_17488_1 1294265.JCM21738_1552 5.42e-84 255.0 COG0697@1|root,COG0697@2|Bacteria,1TR6G@1239|Firmicutes,4HAMD@91061|Bacilli,1ZCQ3@1386|Bacillus 91061|Bacilli EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily ypaH - - - - - - - - - - - EamA k141_15142_1 1174504.AJTN02000085_gene345 1.75e-54 174.0 COG1670@1|root,COG1670@2|Bacteria,1V9MA@1239|Firmicutes,4HIFV@91061|Bacilli,1ZRCT@1386|Bacillus 91061|Bacilli J Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_3 k141_15142_2 1329516.JPST01000019_gene2711 2.78e-17 77.0 COG4997@1|root,COG4997@2|Bacteria,1VEG6@1239|Firmicutes,4HKMC@91061|Bacilli,27CBB@186824|Thermoactinomycetaceae 91061|Bacilli S phosphoribosyl-ATP pyrophosphohydrolase - - - - - - - - - - - - PRA-PH k141_26110_2 866895.HBHAL_5088 3.37e-65 207.0 COG1131@1|root,COG1131@2|Bacteria,1TPMQ@1239|Firmicutes,4HA8K@91061|Bacilli,3NG8H@45667|Halobacillus 91061|Bacilli V AAA domain, putative AbiEii toxin, Type IV TA system - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 k141_2028_1 525919.Apre_0072 3.35e-72 239.0 COG3345@1|root,COG3345@2|Bacteria,1TQF4@1239|Firmicutes,2489F@186801|Clostridia 186801|Clostridia G alpha-galactosidase - - 3.2.1.22 ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 - R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091 RC00049,RC00059,RC00451 ko00000,ko00001,ko01000 - - - Glyco_hydro_36C,Glyco_hydro_36N,Melibiase k141_29485_2 674977.VMC_29000 1.79e-42 148.0 COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,1XTPV@135623|Vibrionales 135623|Vibrionales O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain degS - - ko:K04691 - - - - ko00000,ko01000,ko01002 - - - PDZ_2,Trypsin_2 k141_3281_1 1380408.AVGH01000022_gene1889 5.96e-32 118.0 COG0671@1|root,COG0671@2|Bacteria,1V33Y@1239|Firmicutes,4HM86@91061|Bacilli,21WY4@150247|Anoxybacillus 91061|Bacilli I Acid phosphatase homologues - - 3.6.1.27 ko:K19302 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - PAP2 k141_21040_1 218284.CCDN010000002_gene2030 5.09e-34 127.0 COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,4HA6M@91061|Bacilli,1ZB9G@1386|Bacillus 91061|Bacilli J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family rlmCD GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070041,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.190 ko:K03215 - - - - ko00000,ko01000,ko03009 - - - TRAM,tRNA_U5-meth_tr k141_5836_2 223926.28809248 6.88e-59 182.0 COG0640@1|root,COG0640@2|Bacteria,1N72Q@1224|Proteobacteria,1SCH5@1236|Gammaproteobacteria,1XYDG@135623|Vibrionales 135623|Vibrionales K Transcriptional regulator ArsR family - - - - - - - - - - - - HTH_20,HTH_5 k141_5836_3 1116375.VEJY3_19671 6.58e-79 236.0 COG2391@1|root,COG2391@2|Bacteria,1MZ3A@1224|Proteobacteria,1S95T@1236|Gammaproteobacteria,1XY5J@135623|Vibrionales 135623|Vibrionales S Sulphur transport - - - ko:K07112 - - - - ko00000 - - - Sulf_transp k141_5836_4 1116375.VEJY3_19676 8.03e-86 254.0 COG2391@1|root,COG2391@2|Bacteria,1MZC0@1224|Proteobacteria,1S8UB@1236|Gammaproteobacteria,1XXV5@135623|Vibrionales 135623|Vibrionales S Transporter Component - - - ko:K07112 - - - - ko00000 - - - Sulf_transp k141_5836_5 1116375.VEJY3_19681 0.0 1935.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1XV2Y@135623|Vibrionales 135623|Vibrionales V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran k141_5836_6 1116375.VEJY3_19686 2.71e-210 586.0 COG0845@1|root,COG0845@2|Bacteria,1NQZ0@1224|Proteobacteria,1RR67@1236|Gammaproteobacteria,1XWM1@135623|Vibrionales 135623|Vibrionales M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - - - - - - - - - - HlyD_D23 k141_5836_7 1280001.BAOA01000138_gene1984 3.16e-109 318.0 COG3495@1|root,COG3495@2|Bacteria,1RB8H@1224|Proteobacteria,1SWTP@1236|Gammaproteobacteria,1XX20@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF3299) - - - ko:K09950 - - - - ko00000 - - - DUF3299 k141_5836_8 674977.VMC_32240 1.08e-161 457.0 COG0708@1|root,COG0708@2|Bacteria,1RBRF@1224|Proteobacteria,1S2T0@1236|Gammaproteobacteria,1XVH6@135623|Vibrionales 135623|Vibrionales L Endonuclease/Exonuclease/phosphatase family - - - - - - - - - - - - Exo_endo_phos k141_5836_9 1280001.BAOA01000138_gene1992 0.0 1001.0 COG1328@1|root,COG1328@2|Bacteria,1MWMS@1224|Proteobacteria,1RNHS@1236|Gammaproteobacteria,1XU99@135623|Vibrionales 135623|Vibrionales F Ribonucleoside-triphosphate reductase nrdD - 1.1.98.6 ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R11633,R11634,R11635,R11636 RC00613 ko00000,ko00001,ko00002,ko01000 - - - ATP-cone,NRDD k141_16415_1 1313172.YM304_12760 2.87e-06 55.1 COG1361@1|root,COG1361@2|Bacteria 2|Bacteria M extracellular matrix structural constituent - - - - - - - - - - - - CHU_C,DUF11,SdrD_B k141_28105_1 796606.BMMGA3_13990 1.42e-162 466.0 COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,4H9NW@91061|Bacilli,1ZCU1@1386|Bacillus 91061|Bacilli L RNA-directed DNA polymerase (reverse transcriptase) - - 2.7.7.49 ko:K00986 - - - - ko00000,ko01000 - - - GIIM,RVT_1 k141_20092_2 1279017.AQYJ01000018_gene794 6.53e-36 128.0 COG3148@1|root,COG3148@2|Bacteria,1MZCN@1224|Proteobacteria,1S977@1236|Gammaproteobacteria,468UJ@72275|Alteromonadaceae 1236|Gammaproteobacteria S DTW - - - ko:K05812 - - - - ko00000 - - - DTW k141_22511_1 1117647.M5M_16790 3.62e-57 195.0 COG3934@1|root,COG3934@2|Bacteria,1R6H5@1224|Proteobacteria,1RPMT@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Pkd domain containing protein - - - - - - - - - - - - CBM_35,Cellulase k141_35562_3 1279017.AQYJ01000028_gene2349 5.37e-52 167.0 COG4633@1|root,COG4633@2|Bacteria,1N1UQ@1224|Proteobacteria,1S9HX@1236|Gammaproteobacteria,467WZ@72275|Alteromonadaceae 1236|Gammaproteobacteria S Cupredoxin-like domain - - - - - - - - - - - - Cupredoxin_1 k141_2029_1 42565.FP66_10285 2.99e-105 309.0 COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,1RPBB@1236|Gammaproteobacteria,1XIQ5@135619|Oceanospirillales 135619|Oceanospirillales I Belongs to the CDP-alcohol phosphatidyltransferase class-I family pssA - 2.7.8.8 ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 M00093 R01800 RC00002,RC00017,RC02795 ko00000,ko00001,ko00002,ko01000 - - - CDP-OH_P_transf k141_2029_2 1178482.BJB45_00920 3.1e-26 103.0 COG0059@1|root,COG0059@2|Bacteria,1MV7M@1224|Proteobacteria,1RNA8@1236|Gammaproteobacteria,1XIH7@135619|Oceanospirillales 135619|Oceanospirillales EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate ilvC - 1.1.1.86 ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R03051,R04439,R04440,R05068,R05069,R05071 RC00726,RC00836,RC00837,RC01726 ko00000,ko00001,ko00002,ko01000 - - - IlvC,IlvN k141_17490_1 1116375.VEJY3_12670 4.09e-213 606.0 COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,1RNBF@1236|Gammaproteobacteria,1XUR3@135623|Vibrionales 135623|Vibrionales J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction pnp GO:0003674,GO:0003824,GO:0004654,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.8 ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 M00394 R00437,R00438,R00439,R00440 RC02795 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 - - - KH_1,PNPase,RNase_PH,RNase_PH_C,S1 k141_15143_1 42565.FP66_02680 6.87e-113 328.0 COG2961@1|root,COG2961@2|Bacteria,1MWGA@1224|Proteobacteria,1RNI1@1236|Gammaproteobacteria,1XJV8@135619|Oceanospirillales 135619|Oceanospirillales S Specifically methylates the adenine in position 2030 of 23S rRNA rlmJ - 2.1.1.266 ko:K07115 - - - - ko00000,ko01000,ko03009 - - - RsmJ k141_3282_1 1295642.H839_12019 2.26e-44 150.0 29P42@1|root,30A29@2|Bacteria,1V423@1239|Firmicutes,4HH8N@91061|Bacilli,1WG73@129337|Geobacillus 91061|Bacilli S Protein of unknown function (DUF3907) ypuI - - - - - - - - - - - DUF3907 k141_5838_1 1128421.JAGA01000002_gene283 1.78e-46 155.0 COG0629@1|root,COG0629@2|Bacteria,2NPUB@2323|unclassified Bacteria 2|Bacteria L Single-strand binding protein family ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k141_24780_1 1453501.JELR01000002_gene1342 3.74e-100 316.0 COG1629@1|root,COG4771@2|Bacteria,1MWKN@1224|Proteobacteria,1RNWV@1236|Gammaproteobacteria,4660S@72275|Alteromonadaceae 1236|Gammaproteobacteria P TonB-dependent Receptor Plug Domain - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_1125_1 1116375.VEJY3_16486 1.19e-172 504.0 COG1129@1|root,COG4177@1|root,COG1129@2|Bacteria,COG4177@2|Bacteria,1R9IW@1224|Proteobacteria,1T36F@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Belongs to the binding-protein-dependent transport system permease family - - - ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C,BPD_transp_2 k141_28106_2 218284.CCDN010000007_gene3913 7.94e-88 268.0 COG2133@1|root,COG2133@2|Bacteria,1TR38@1239|Firmicutes,4HBME@91061|Bacilli,1ZC94@1386|Bacillus 91061|Bacilli G COG2133 Glucose sorbosone dehydrogenases - - - - - - - - - - - - GSDH k141_5839_2 218284.CCDN010000001_gene1745 8.84e-28 108.0 28JAJ@1|root,2Z95C@2|Bacteria,1UBFJ@1239|Firmicutes,4HHFM@91061|Bacilli,1ZR76@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_31590_1 218284.CCDN010000002_gene2177 1e-80 246.0 COG0714@1|root,COG0714@2|Bacteria,1TPKR@1239|Firmicutes,4HDUX@91061|Bacilli,1ZAQ6@1386|Bacillus 91061|Bacilli S ATPase family associated with various cellular activities (AAA) - - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 k141_31590_2 218284.CCDN010000002_gene2176 7.62e-20 87.8 28I6X@1|root,2Z89S@2|Bacteria,1TQMI@1239|Firmicutes,4HD5B@91061|Bacilli,1ZD3B@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF4350) - - - - - - - - - - - - DUF4350 k141_37710_1 662479.C440_10378 9.73e-39 143.0 COG1257@1|root,arCOG04260@2157|Archaea,2XTV9@28890|Euryarchaeota,23S4F@183963|Halobacteria 183963|Halobacteria I Belongs to the HMG-CoA reductase family hmgA - 1.1.1.34 ko:K00021 ko00900,ko01100,ko01110,ko01130,ko04152,ko04976,map00900,map01100,map01110,map01130,map04152,map04976 M00095 R02082 RC00004,RC00644 ko00000,ko00001,ko00002,ko01000 - - - HMG-CoA_red k141_4517_1 218284.CCDN010000008_gene4185 2.78e-89 284.0 COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,4HAG1@91061|Bacilli,1ZARG@1386|Bacillus 91061|Bacilli J Belongs to the class-I aminoacyl-tRNA synthetase family leuS GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Anticodon_1,tRNA-synt_1,tRNA-synt_1_2 k141_24808_1 1279017.AQYJ01000023_gene3124 4.7e-124 378.0 COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,465W3@72275|Alteromonadaceae 1236|Gammaproteobacteria T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - GAF_2,HAMP,HATPase_c,HisKA,Hpt,NMT1,PAS,PAS_3,PAS_4,PAS_9,Response_reg k141_5882_1 1294265.JCM21738_4274 4.57e-152 440.0 COG0477@1|root,COG2814@2|Bacteria,1TPRN@1239|Firmicutes,4H9VV@91061|Bacilli,1ZAXQ@1386|Bacillus 91061|Bacilli EGP the major facilitator superfamily - - - - - - - - - - - - MFS_1 k141_2049_2 218284.CCDN010000007_gene3980 1.85e-151 432.0 COG2890@1|root,COG2890@2|Bacteria,1TSMA@1239|Firmicutes,4HC6W@91061|Bacilli,1ZBSE@1386|Bacillus 91061|Bacilli J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif prmC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 ko:K02493 - - R10806 RC00003,RC03279 ko00000,ko01000,ko03012 - - - MTS k141_20111_1 1116375.VEJY3_10445 0.0 2142.0 COG1305@1|root,COG4196@1|root,COG1305@2|Bacteria,COG4196@2|Bacteria,1MVAG@1224|Proteobacteria,1RMX2@1236|Gammaproteobacteria,1Y0NC@135623|Vibrionales 135623|Vibrionales E Putative amidoligase enzyme (DUF2126) - - - - - - - - - - - - Bact_transglu_N,DUF2126,Transglut_core k141_20111_2 1116375.VEJY3_10440 4.52e-211 585.0 COG2307@1|root,COG2307@2|Bacteria,1MVZK@1224|Proteobacteria,1RN2Y@1236|Gammaproteobacteria,1XZXU@135623|Vibrionales 135623|Vibrionales S A predicted alpha-helical domain with a conserved ER motif. - - - - - - - - - - - - Alpha-E k141_20111_3 1116375.VEJY3_10435 0.0 953.0 COG2308@1|root,COG2308@2|Bacteria,1MUAD@1224|Proteobacteria,1RNAF@1236|Gammaproteobacteria,1Y0FR@135623|Vibrionales 135623|Vibrionales S Circularly permuted ATP-grasp type 2 - - - - - - - - - - - - CP_ATPgrasp_2 k141_20111_4 223926.28806359 1.32e-89 268.0 COG0406@1|root,COG0406@2|Bacteria,1NPC4@1224|Proteobacteria,1RSEU@1236|Gammaproteobacteria,1XWAT@135623|Vibrionales 135623|Vibrionales G Phosphoglycerate mutase family - - - - - - - - - - - - His_Phos_1 k141_20111_5 1051646.VITU9109_24615 8.07e-113 327.0 COG1280@1|root,COG1280@2|Bacteria,1MYQ6@1224|Proteobacteria,1S7GH@1236|Gammaproteobacteria,1XXF7@135623|Vibrionales 135623|Vibrionales E LysE type translocator - - - - - - - - - - - - LysE k141_20111_6 1051646.VITU9109_24610 4.29e-167 471.0 COG2207@1|root,COG2207@2|Bacteria,1R46K@1224|Proteobacteria,1RNCY@1236|Gammaproteobacteria,1XV7U@135623|Vibrionales 135623|Vibrionales K AraC-like ligand binding domain - - - - - - - - - - - - AraC_binding,HTH_18,HTH_AraC k141_20111_7 1116375.VEJY3_10415 1.39e-57 181.0 2CU0I@1|root,32SUF@2|Bacteria,1N43R@1224|Proteobacteria,1SBBN@1236|Gammaproteobacteria,1XYTB@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_20111_8 1116375.VEJY3_10410 0.0 1157.0 COG4232@1|root,COG4233@1|root,COG4232@2|Bacteria,COG4233@2|Bacteria,1MU8W@1224|Proteobacteria,1RPF7@1236|Gammaproteobacteria,1XTSN@135623|Vibrionales 135623|Vibrionales CO to be involved in C-type cytochrome biogenesis - - - ko:K08344 - - - - ko00000,ko02000 5.A.1.5 - - DsbC,DsbD,Thioredoxin_7 k141_20111_9 1116375.VEJY3_10405 1.29e-89 266.0 COG0526@1|root,COG0526@2|Bacteria,1RHPC@1224|Proteobacteria,1S4C9@1236|Gammaproteobacteria,1XXTA@135623|Vibrionales 135623|Vibrionales CO COG0526 Thiol-disulfide isomerase and thioredoxins - - - - - - - - - - - - AhpC-TSA,Thioredoxin k141_20111_10 223926.28806996 8.74e-125 355.0 28PFD@1|root,2ZC6I@2|Bacteria,1R8PT@1224|Proteobacteria,1S2BA@1236|Gammaproteobacteria,1XWFU@135623|Vibrionales 135623|Vibrionales - - VP2004 - - - - - - - - - - - - k141_20111_11 223926.28806995 1.21e-130 373.0 COG4976@1|root,COG4976@2|Bacteria,1MXUV@1224|Proteobacteria,1S58I@1236|Gammaproteobacteria,1XXHF@135623|Vibrionales 135623|Vibrionales S Methyltransferase domain - - - - - - - - - - - - Methyltransf_31 k141_20111_12 223926.28806994 1.32e-110 325.0 COG0500@1|root,COG0500@2|Bacteria 2|Bacteria Q methyltransferase activity - - - - - - - - - - - - Methyltransf_23,Methyltransf_25,Methyltransf_31,TehB k141_16672_2 55601.VANGNB10_cII0911c 5.03e-129 371.0 COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,1S1FS@1236|Gammaproteobacteria,1XT07@135623|Vibrionales 135623|Vibrionales P Phosphate transport system permease - - - ko:K02038 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 k141_32124_1 1385513.N780_19035 7.79e-11 60.5 2ECBP@1|root,336A1@2|Bacteria,1VIYR@1239|Firmicutes,4HPVZ@91061|Bacilli,2YBQE@289201|Pontibacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_32124_2 675817.VDA_000467 1.09e-11 66.2 COG1011@1|root,COG1011@2|Bacteria,1MVF8@1224|Proteobacteria,1RMK3@1236|Gammaproteobacteria,1XSVE@135623|Vibrionales 135623|Vibrionales S hydrolase (HAD superfamily) yjjG - 3.1.3.5 ko:K08723 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 k141_9532_1 1174504.AJTN02000028_gene1761 7.24e-09 57.0 COG1396@1|root,COG1396@2|Bacteria,1UV6T@1239|Firmicutes,4I1D1@91061|Bacilli 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_3 k141_9532_2 1423734.JCM14202_1015 0.000414 43.9 COG1476@1|root,COG1476@2|Bacteria,1V36C@1239|Firmicutes,4HHGI@91061|Bacilli,3FCE5@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix domain - - - - - - - - - - - - HTH_3 k141_28590_1 1042377.AFPJ01000053_gene1506 3.15e-94 301.0 COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,1RN05@1236|Gammaproteobacteria,46A1V@72275|Alteromonadaceae 1236|Gammaproteobacteria S Insulinase (Peptidase family M16) ptrA - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C k141_5997_1 1453501.JELR01000001_gene1941 1.41e-96 305.0 COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,1RMAP@1236|Gammaproteobacteria,464XP@72275|Alteromonadaceae 1236|Gammaproteobacteria M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamA GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - ko:K07277 - - - - ko00000,ko02000,ko03029 1.B.33 - - Bac_surface_Ag,POTRA k141_21438_2 218284.CCDN010000001_gene1796 1.15e-83 248.0 COG0789@1|root,COG0789@2|Bacteria,1V6JE@1239|Firmicutes,4HKM6@91061|Bacilli,1ZH1F@1386|Bacillus 91061|Bacilli K transcriptional glnR GO:0003674,GO:0005488,GO:0005515,GO:0006082,GO:0006355,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016053,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031326,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903506,GO:2000112,GO:2001141 - ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000,ko03000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - MerR_1 k141_23810_1 1177154.Y5S_01785 3.78e-16 78.6 COG1502@1|root,COG1502@2|Bacteria,1MUDJ@1224|Proteobacteria,1RMIF@1236|Gammaproteobacteria,1XN8A@135619|Oceanospirillales 135619|Oceanospirillales I COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes - - - ko:K06132 ko00564,ko01100,map00564,map01100 - R11062 RC00017 ko00000,ko00001,ko01000 - - - PLDc_2 k141_35714_1 330084.JNYZ01000040_gene4972 3.67e-15 79.0 COG0697@1|root,COG0697@2|Bacteria,2GK49@201174|Actinobacteria,4DZB8@85010|Pseudonocardiales 201174|Actinobacteria EG EamA-like transporter family - - - - - - - - - - - - EamA k141_4812_3 42256.RradSPS_2367 2.84e-22 96.3 COG0589@1|root,COG1592@1|root,COG1773@1|root,COG0589@2|Bacteria,COG1592@2|Bacteria,COG1773@2|Bacteria 2|Bacteria C rubredoxin hrb - 1.6.3.4 ko:K22405 - - - - ko00000,ko01000 - - - Flavin_Reduct,Lactamase_B,Rubredoxin,Rubrerythrin,Usp k141_28591_1 42565.FP66_01480 1.75e-23 97.1 COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,1RMN5@1236|Gammaproteobacteria,1XHM6@135619|Oceanospirillales 135619|Oceanospirillales S Permease lptF - - ko:K07091 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko02000 1.B.42.1 - - YjgP_YjgQ k141_28591_2 42565.FP66_01475 6.6e-95 285.0 COG0795@1|root,COG0795@2|Bacteria,1MVW3@1224|Proteobacteria,1RM8H@1236|Gammaproteobacteria,1XIT5@135619|Oceanospirillales 135619|Oceanospirillales S permease lptG - - ko:K11720 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko02000 1.B.42.1 - - YjgP_YjgQ k141_3626_1 218284.CCDN010000002_gene2114 4.23e-157 446.0 COG3508@1|root,COG3508@2|Bacteria,1UYZ0@1239|Firmicutes,4HCCC@91061|Bacilli,1ZC6Q@1386|Bacillus 91061|Bacilli Q homogentisate 12-dioxygenase hmgA - 1.13.11.5 ko:K00451 ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120 M00044 R02519 RC00737 ko00000,ko00001,ko00002,ko01000 - - - HgmA k141_22629_2 243365.CV_1801 2.26e-08 57.4 28IVS@1|root,2Z8U4@2|Bacteria,1NH4A@1224|Proteobacteria,2VZWF@28216|Betaproteobacteria 28216|Betaproteobacteria S EthD domain - - - - - - - - - - - - EthD k141_23811_1 1211814.CAPG01000038_gene2232 1.37e-59 200.0 COG0843@1|root,COG0843@2|Bacteria,1TP2U@1239|Firmicutes,4HA4X@91061|Bacilli,1ZBD5@1386|Bacillus 91061|Bacilli C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B ctaD GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009486,GO:0009987,GO:0015002,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0034220,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.9.3.1 ko:K02274 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6 - - COX1 k141_21440_1 880073.Calab_0428 2.98e-23 101.0 COG0515@1|root,COG0515@2|Bacteria,2NPFQ@2323|unclassified Bacteria 2|Bacteria KLT Serine threonine protein kinase - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - Pkinase k141_15512_1 218284.CCDN010000001_gene1047 5.2e-81 241.0 2AF43@1|root,3152T@2|Bacteria,1VFMI@1239|Firmicutes,4HIN3@91061|Bacilli,1ZGZY@1386|Bacillus 91061|Bacilli S Stage V sporulation protein AB spoVAB - - ko:K06404 - - - - ko00000 - - - SpoVAB k141_15512_2 218284.CCDN010000001_gene1046 9.34e-102 299.0 28PNE@1|root,2ZCB6@2|Bacteria,1V214@1239|Firmicutes,4HFTI@91061|Bacilli,1ZBVY@1386|Bacillus 91061|Bacilli S Stage V sporulation protein AA spoVAA - - ko:K06403 - - - - ko00000 - - - SporV_AA k141_16674_1 342610.Patl_2231 3.86e-55 195.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria 1236|Gammaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran k141_14315_1 553385.JEMF01000006_gene3392 1.72e-24 94.7 COG0096@1|root,COG0096@2|Bacteria,1RDG3@1224|Proteobacteria,1S452@1236|Gammaproteobacteria,1XJMV@135619|Oceanospirillales 135619|Oceanospirillales J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit rpsH - - ko:K02994 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S8 k141_14315_2 42565.FP66_06560 9.82e-63 192.0 COG0199@1|root,COG0199@2|Bacteria,1MZDT@1224|Proteobacteria,1S62N@1236|Gammaproteobacteria,1XKDP@135619|Oceanospirillales 135619|Oceanospirillales J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site rpsN - - ko:K02954 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S14 k141_19059_1 1279017.AQYJ01000026_gene306 1.24e-126 382.0 COG2274@1|root,COG2274@2|Bacteria,1R2T0@1224|Proteobacteria,1SBE1@1236|Gammaproteobacteria,464I6@72275|Alteromonadaceae 1236|Gammaproteobacteria V COG2274 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain cvaB - - ko:K06147,ko:K13409 ko02010,ko04626,map02010,map04626 M00339 - - ko00000,ko00001,ko00002,ko02000,ko02044 3.A.1.106,3.A.1.109,3.A.1.110,3.A.1.21 - - ABC_membrane,ABC_tran,Peptidase_C39,cNMP_binding k141_19059_2 1328313.DS2_13539 8.74e-94 295.0 COG0845@1|root,COG0845@2|Bacteria,1R3R4@1224|Proteobacteria,1RNSG@1236|Gammaproteobacteria,4666Y@72275|Alteromonadaceae 1236|Gammaproteobacteria M HlyD family secretion protein - - - ko:K13408 ko04626,map04626 M00339 - - ko00000,ko00001,ko00002,ko02000,ko02044 8.A.1 - - Biotin_lipoyl_2,HlyD_3 k141_19059_3 1217718.ALOU01000034_gene2891 5.47e-14 71.2 COG2843@1|root,COG2843@2|Bacteria,1P1MG@1224|Proteobacteria,2VIGZ@28216|Betaproteobacteria,1K5QX@119060|Burkholderiaceae 28216|Betaproteobacteria M biosynthesis protein - - - ko:K07282 - - - - ko00000 - - - Mur_ligase_M,PGA_cap k141_30959_1 1116375.VEJY3_18421 5.04e-229 634.0 COG0683@1|root,COG0683@2|Bacteria,1MV5T@1224|Proteobacteria,1TIWA@1236|Gammaproteobacteria,1XZU0@135623|Vibrionales 135623|Vibrionales E Periplasmic binding protein - - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 k141_30959_2 1219076.N646_4027 1.38e-181 509.0 COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,1RPTT@1236|Gammaproteobacteria,1XY63@135623|Vibrionales 135623|Vibrionales U Belongs to the binding-protein-dependent transport system permease family - - - ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 k141_20240_1 1304874.JAFY01000002_gene661 8.23e-34 131.0 COG0477@1|root,COG2814@2|Bacteria,3TACG@508458|Synergistetes 508458|Synergistetes EGP PFAM Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 k141_28593_1 42565.FP66_00300 8.09e-79 241.0 COG2084@1|root,COG2084@2|Bacteria,1MUGU@1224|Proteobacteria,1RQ2D@1236|Gammaproteobacteria,1XIV6@135619|Oceanospirillales 135619|Oceanospirillales I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases - - 1.1.1.60 ko:K00042 ko00630,ko01100,map00630,map01100 - R01745,R01747 RC00099 ko00000,ko00001,ko01000 - - - NAD_binding_11,NAD_binding_2 k141_11920_1 218284.CCDN010000001_gene1869 2.75e-112 326.0 COG2188@1|root,COG2188@2|Bacteria,1TQQQ@1239|Firmicutes,4H9TG@91061|Bacilli,1ZB5M@1386|Bacillus 91061|Bacilli K Transcriptional regulator ymfC - - ko:K03710 - - - - ko00000,ko03000 - - - GntR,UTRA k141_23812_1 1294265.JCM21738_2130 1.46e-148 430.0 COG3104@1|root,COG3104@2|Bacteria,1TP81@1239|Firmicutes,4HAF2@91061|Bacilli,1ZAVZ@1386|Bacillus 91061|Bacilli E amino acid peptide transporter dtpT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03305 - - - - ko00000 2.A.17 - - PTR2 k141_22631_1 218284.CCDN010000002_gene2168 8.62e-186 530.0 COG1164@1|root,COG1164@2|Bacteria,1TQ5W@1239|Firmicutes,4HAN9@91061|Bacilli,1ZCRR@1386|Bacillus 91061|Bacilli E COG1164 Oligoendopeptidase F pepF2 - - - - - - - - - - - Peptidase_M3,Peptidase_M3_N k141_3627_2 223926.28809935 2.29e-162 464.0 COG1157@1|root,COG1157@2|Bacteria,1MUH6@1224|Proteobacteria,1RM9W@1236|Gammaproteobacteria,1XSRA@135623|Vibrionales 135623|Vibrionales NU ATP synthase alpha/beta family, nucleotide-binding domain - - 3.6.3.14 ko:K02412 ko02040,map02040 - - - ko00000,ko00001,ko01000,ko02035,ko02044 3.A.6.2,3.A.6.3 - - ATP-synt_ab k141_16675_1 926550.CLDAP_08280 4.23e-63 211.0 COG0578@1|root,COG0578@2|Bacteria,2G63S@200795|Chloroflexi 200795|Chloroflexi C PFAM FAD dependent oxidoreductase - - 1.1.5.3 ko:K00111 ko00564,ko01110,map00564,map01110 - R00848 RC00029 ko00000,ko00001,ko01000 - - - DAO,Fer2_BFD k141_36881_1 1294265.JCM21738_3647 1.08e-76 230.0 COG2919@1|root,COG2919@2|Bacteria,1VKC5@1239|Firmicutes,4HR53@91061|Bacilli,1ZIBZ@1386|Bacillus 91061|Bacilli D Septum formation initiator divIC - - ko:K13052 - - - - ko00000,ko03036 - - - DivIC k141_36881_2 1294265.JCM21738_3648 1.52e-96 281.0 COG1098@1|root,COG1098@2|Bacteria,1V6FE@1239|Firmicutes,4HIKM@91061|Bacilli,1ZG7S@1386|Bacillus 91061|Bacilli J RNA binding protein (contains ribosomal protein S1 domain) yabR - - ko:K07571 - - - - ko00000 - - - S1 k141_34512_1 1453501.JELR01000001_gene1904 1.49e-168 485.0 COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,1RP55@1236|Gammaproteobacteria,465RX@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1178 ABC-type Fe3 transport system, permease component sfuB - - ko:K02011 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - BPD_transp_1 k141_34512_2 1453501.JELR01000001_gene1903 6.81e-194 543.0 COG1840@1|root,COG1840@2|Bacteria,1MUEG@1224|Proteobacteria,1S88G@1236|Gammaproteobacteria,465QY@72275|Alteromonadaceae 1236|Gammaproteobacteria P ABC-type Fe3 transport system, periplasmic component - - - ko:K02012 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - iJN746.PP_4881 SBP_bac_6 k141_34512_3 1042377.AFPJ01000037_gene2938 8.32e-17 77.8 28HUI@1|root,2Z818@2|Bacteria,1P2BF@1224|Proteobacteria,1RQM2@1236|Gammaproteobacteria,465PQ@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_33328_1 1116375.VEJY3_03220 1.68e-247 692.0 COG2199@1|root,COG3706@2|Bacteria,1MXAW@1224|Proteobacteria,1RZ41@1236|Gammaproteobacteria,1XSZZ@135623|Vibrionales 135623|Vibrionales T COG2199 FOG GGDEF domain VP0699 - - - - - - - - - - - GGDEF k141_33328_2 223926.28805684 9.99e-271 745.0 COG1611@1|root,COG1611@2|Bacteria,1MVQJ@1224|Proteobacteria,1RQHX@1236|Gammaproteobacteria,1XVEP@135623|Vibrionales 135623|Vibrionales S Rossmann fold nucleotide-binding protein ygdH - 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - DUF3412,DUF4478,Lysine_decarbox k141_3628_2 171693.BN988_01466 7.71e-11 57.8 28QE5@1|root,2ZCWH@2|Bacteria,1W3GQ@1239|Firmicutes,4HZWK@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - k141_3628_3 1384049.CD29_15420 1.58e-42 148.0 COG3173@1|root,COG3173@2|Bacteria,1UZ6J@1239|Firmicutes,4HEYZ@91061|Bacilli,3IYET@400634|Lysinibacillus 91061|Bacilli S Phosphotransferase enzyme family - - - - - - - - - - - - APH k141_53_2 218284.CCDN010000007_gene3830 3.23e-110 328.0 COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,4HA31@91061|Bacilli,1ZBNF@1386|Bacillus 91061|Bacilli O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain yyxA - 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Trypsin_2 k141_1202_1 1116375.VEJY3_15090 3.08e-251 693.0 COG3071@1|root,COG3071@2|Bacteria,1MU7A@1224|Proteobacteria,1RMRG@1236|Gammaproteobacteria,1XT4E@135623|Vibrionales 135623|Vibrionales H enzyme of heme biosynthesis hemY - - ko:K02498 - - - - ko00000 - - - HemY_N,TPR_16,TPR_19,TPR_2 k141_1202_2 1116375.VEJY3_15085 6e-217 607.0 COG2959@1|root,COG2959@2|Bacteria,1MY3A@1224|Proteobacteria,1RNJY@1236|Gammaproteobacteria,1XU9X@135623|Vibrionales 135623|Vibrionales H Uroporphyrin-III C-methyltransferase hemX - 2.1.1.107 ko:K02496 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R03194 RC00003,RC00871 ko00000,ko00001,ko00002,ko01000 - - - HemX k141_1202_3 1116375.VEJY3_15080 4.38e-157 442.0 COG1587@1|root,COG1587@2|Bacteria,1MWZD@1224|Proteobacteria,1RM9K@1236|Gammaproteobacteria,1XSK6@135623|Vibrionales 135623|Vibrionales H Uroporphyrinogen-III synthase hemD - 4.2.1.75 ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R03165 RC01861 ko00000,ko00001,ko00002,ko01000 - - - HEM4 k141_1202_4 1116375.VEJY3_15075 3.23e-219 605.0 COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,1RMQ8@1236|Gammaproteobacteria,1XSM4@135623|Vibrionales 135623|Vibrionales H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps hemC GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00084 RC02317 ko00000,ko00001,ko00002,ko01000 - - - Porphobil_deam,Porphobil_deamC k141_1202_5 1116375.VEJY3_15070 0.0 1625.0 COG3072@1|root,COG3072@2|Bacteria,1PI5T@1224|Proteobacteria,1RMPZ@1236|Gammaproteobacteria,1XUEA@135623|Vibrionales 135623|Vibrionales F Adenylate cyclase cyaA - 4.6.1.1 ko:K05851 ko00230,ko02026,ko05111,map00230,map02026,map05111 - R00089,R00434 RC00295 ko00000,ko00001,ko01000 - - - Adenyl_cycl_N,Adenylate_cycl k141_1202_6 223926.28808012 5.59e-68 206.0 COG1965@1|root,COG1965@2|Bacteria,1RH9A@1224|Proteobacteria,1S5UP@1236|Gammaproteobacteria,1XXUN@135623|Vibrionales 135623|Vibrionales P Belongs to the frataxin family cyaY GO:0003674,GO:0003824,GO:0004322,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006790,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008198,GO:0008199,GO:0009987,GO:0016043,GO:0016226,GO:0016491,GO:0016530,GO:0016722,GO:0016724,GO:0018282,GO:0018283,GO:0019538,GO:0019725,GO:0022607,GO:0030003,GO:0031163,GO:0033554,GO:0034599,GO:0034986,GO:0036211,GO:0042221,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0050896,GO:0051186,GO:0051536,GO:0051537,GO:0051540,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071704,GO:0071840,GO:0098771,GO:0140104,GO:1901564 - ko:K06202 - - - - ko00000 - - - Frataxin_Cyay k141_1202_7 1116375.VEJY3_15055 1.99e-298 814.0 COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,1RMI2@1236|Gammaproteobacteria,1XSWN@135623|Vibrionales 135623|Vibrionales E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine lysA GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008836,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N,Orn_DAP_Arg_deC k141_1202_8 223926.28808009 1.03e-197 548.0 COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,1RMGV@1236|Gammaproteobacteria,1XSPK@135623|Vibrionales 135623|Vibrionales E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan dapF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 - - - DAP_epimerase k141_1202_9 1116375.VEJY3_15045 6.09e-155 436.0 COG3159@1|root,COG3159@2|Bacteria,1R4BP@1224|Proteobacteria,1S953@1236|Gammaproteobacteria,1Y2KI@135623|Vibrionales 135623|Vibrionales S Protein of unknown function, DUF484 - - - ko:K09921 - - - - ko00000 - - - DUF484 k141_1202_10 1116375.VEJY3_15040 2.85e-214 592.0 COG4973@1|root,COG4973@2|Bacteria,1MUJJ@1224|Proteobacteria,1RMJG@1236|Gammaproteobacteria,1XSJQ@135623|Vibrionales 135623|Vibrionales D Belongs to the 'phage' integrase family. XerC subfamily xerC GO:0000150,GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009009,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140097,GO:1901360 - ko:K03733 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase k141_1202_11 1116375.VEJY3_15035 1.44e-144 410.0 COG1011@1|root,COG1011@2|Bacteria,1N0I6@1224|Proteobacteria,1RQ41@1236|Gammaproteobacteria,1XTVY@135623|Vibrionales 135623|Vibrionales S hydrolase (HAD superfamily) - - 3.1.3.102,3.1.3.104 ko:K20862 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00548,R07280 RC00017 ko00000,ko00001,ko00002,ko01000 - - - HAD_2 k141_1202_12 1116375.VEJY3_15030 6.01e-115 332.0 COG3148@1|root,COG3148@2|Bacteria,1N8XY@1224|Proteobacteria,1RS6H@1236|Gammaproteobacteria,1XWXG@135623|Vibrionales 135623|Vibrionales S DTW - - - - - - - - - - - - DTW k141_1202_13 223926.28808003 1.04e-205 580.0 COG3650@1|root,COG3650@2|Bacteria,1RIIM@1224|Proteobacteria,1S8NS@1236|Gammaproteobacteria,1XSAK@135623|Vibrionales 135623|Vibrionales S response to hydrogen peroxide VP2977 - - ko:K08985 - - - - ko00000 - - - - k141_17888_2 1294265.JCM21738_4084 6.59e-15 72.4 COG0325@1|root,COG0325@2|Bacteria,1TRDN@1239|Firmicutes,4HC45@91061|Bacilli,1ZARM@1386|Bacillus 91061|Bacilli S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis ylmE GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 - ko:K06997 - - - - ko00000 - - - Ala_racemase_N k141_10726_1 1211814.CAPG01000076_gene3538 9.36e-58 193.0 COG1823@1|root,COG1823@2|Bacteria,1UPUK@1239|Firmicutes,4HAJY@91061|Bacilli,1ZB7C@1386|Bacillus 91061|Bacilli U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family tcyP - - ko:K06956 - - - - ko00000 - - - SDF k141_8388_1 1131553.JIBI01000033_gene2347 1.55e-127 374.0 COG2856@1|root,COG2856@2|Bacteria,1N6JN@1224|Proteobacteria 1224|Proteobacteria E Zn peptidase - - - - - - - - - - - - Peptidase_M78 k141_8388_2 1470591.BW41_02157 0.000315 48.9 COG4271@1|root,COG4271@2|Bacteria,1QZQR@1224|Proteobacteria 1224|Proteobacteria K FRG - - - - - - - - - - - - FRG k141_21441_1 218284.CCDN010000002_gene2065 1.77e-66 202.0 2D1ET@1|root,32TAJ@2|Bacteria,1V8Q4@1239|Firmicutes,4HQUW@91061|Bacilli,1ZI5D@1386|Bacillus 91061|Bacilli S Cell division protein FtsJ - - - - - - - - - - - - - k141_35717_1 501479.ACNW01000048_gene282 4.06e-113 344.0 COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,2TRH3@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction pnp GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 M00394 R00437,R00438,R00439,R00440 RC02795 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 - - - KH_1,PNPase,RNase_PH,RNase_PH_C,S1 k141_29741_1 1116375.VEJY3_03440 3.73e-196 555.0 COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,1RPX3@1236|Gammaproteobacteria,1XUQ9@135623|Vibrionales 135623|Vibrionales F Belongs to the 5'-nucleotidase family ushA GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0009225,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034641,GO:0042578,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901360 3.1.3.5,3.6.1.45 ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - 5_nucleotid_C,Metallophos k141_30983_2 218284.CCDN010000001_gene656 5.47e-26 106.0 COG1055@1|root,COG1055@2|Bacteria,1TPNN@1239|Firmicutes,4HAIC@91061|Bacilli,1ZBBN@1386|Bacillus 91061|Bacilli P Membrane arsB_2 - - ko:K03893 - - - - ko00000,ko02000 2.A.45.1,3.A.4.1 - - CitMHS k141_7171_1 1453501.JELR01000002_gene132 3.74e-80 264.0 COG0591@1|root,COG0784@1|root,COG4191@1|root,COG0591@2|Bacteria,COG0784@2|Bacteria,COG4191@2|Bacteria,1QTSW@1224|Proteobacteria,1T1G2@1236|Gammaproteobacteria,46D5M@72275|Alteromonadaceae 1236|Gammaproteobacteria T PAS fold - - - - - - - - - - - - HATPase_c,HisKA,PAS_4,PAS_7,Response_reg,SSF k141_29765_1 1462527.CCDM010000005_gene5051 1.8e-07 53.1 2CHUT@1|root,32S6K@2|Bacteria,1VDIM@1239|Firmicutes,4HMTY@91061|Bacilli,23M5T@182709|Oceanobacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_13160_1 1347087.CBYO010000022_gene3455 1.02e-103 317.0 COG1164@1|root,COG1164@2|Bacteria,1TR7D@1239|Firmicutes,4HA0P@91061|Bacilli 91061|Bacilli E oligoendopeptidase F pepF1_3 - - - - - - - - - - - Peptidase_M3,Peptidase_M3_N k141_32138_2 218284.CCDN010000001_gene565 3.45e-12 68.9 28KBQ@1|root,2Z9YP@2|Bacteria,1UZPB@1239|Firmicutes,4HAVU@91061|Bacilli,1ZBPJ@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_22662_1 1469607.KK073768_gene476 4.69e-10 66.2 COG0412@1|root,COG0412@2|Bacteria,1G348@1117|Cyanobacteria,1HMUM@1161|Nostocales 1117|Cyanobacteria Q PFAM Dienelactone hydrolase - - 3.1.1.45 ko:K01061 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 - R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222 RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 - - - DLH k141_22662_2 1123242.JH636436_gene430 1.77e-14 74.3 COG0624@1|root,COG0624@2|Bacteria,2IXPJ@203682|Planctomycetes 203682|Planctomycetes E ArgE DapE Acy1 family protein - - 3.5.1.16,3.5.1.18 ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R00669,R02734,R09107 RC00064,RC00090,RC00300 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20 k141_11935_1 1238182.C882_4407 1.31e-89 275.0 COG0738@1|root,COG0738@2|Bacteria,1QUEB@1224|Proteobacteria,2TW8G@28211|Alphaproteobacteria,2JZ69@204441|Rhodospirillales 204441|Rhodospirillales G Sugar (and other) transporter - - - - - - - - - - - - MFS_1,Sugar_tr k141_33342_1 1487953.JMKF01000022_gene2509 4.6e-96 292.0 COG0161@1|root,COG0161@2|Bacteria,1G1QE@1117|Cyanobacteria,1H9SQ@1150|Oscillatoriales 1117|Cyanobacteria E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family bioA - 2.6.1.18,2.6.1.62 ko:K00822,ko:K00833 ko00280,ko00410,ko00640,ko00780,ko01100,map00280,map00410,map00640,map00780,map01100 M00123,M00573,M00577 R00907,R03231,R04187 RC00006,RC00008,RC00062,RC00160,RC00887 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 k141_30984_2 240302.BN982_02479 4.7e-41 144.0 COG1957@1|root,COG1957@2|Bacteria,1TRWG@1239|Firmicutes,4HCMZ@91061|Bacilli 91061|Bacilli F nucleoside hydrolase rihA_1 - 3.2.2.1 ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 - R01245,R01273,R01677,R01770,R02143 RC00033,RC00063,RC00122,RC00318,RC00485 ko00000,ko00001,ko01000 - - - IU_nuc_hydro k141_17912_1 218284.CCDN010000001_gene1489 1.5e-139 418.0 COG0188@1|root,COG0188@2|Bacteria,1TRE7@1239|Firmicutes,4HAQB@91061|Bacilli,1ZBCI@1386|Bacillus 91061|Bacilli L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K02621 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseA_C,DNA_topoisoIV k141_26221_1 1279017.AQYJ01000024_gene1094 0.0 1555.0 COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,1RM9M@1236|Gammaproteobacteria,464S6@72275|Alteromonadaceae 1236|Gammaproteobacteria U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006457,GO:0006605,GO:0006810,GO:0006886,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0034613,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042802,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061077,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW k141_26221_3 1453501.JELR01000001_gene3040 3.58e-207 574.0 COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,1RQ72@1236|Gammaproteobacteria,46506@72275|Alteromonadaceae 1236|Gammaproteobacteria M Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis lpxC GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0008654,GO:0008759,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.5.1.108 ko:K02535 ko00540,ko01100,map00540,map01100 M00060 R04587 RC00166,RC00300 ko00000,ko00001,ko00002,ko01000,ko01005 - - iECS88_1305.ECS88_0100 LpxC k141_26221_4 1279017.AQYJ01000024_gene1091 3.27e-39 142.0 COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,1RPZS@1236|Gammaproteobacteria,46530@72275|Alteromonadaceae 1236|Gammaproteobacteria D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity ftsZ GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022607,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0051258,GO:0051301,GO:0065003,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03531 ko04112,map04112 - - - ko00000,ko00001,ko02048,ko03036,ko04812 - - - FtsZ_C,Tubulin k141_1218_1 1056820.KB900696_gene4097 2.46e-89 272.0 COG4977@1|root,COG4977@2|Bacteria,1QTV9@1224|Proteobacteria 1224|Proteobacteria K Transcriptional regulator - - - - - - - - - - - - AraC_N,HTH_18,HTH_AraC k141_1218_2 1353531.AZNX01000043_gene4054 9.23e-78 239.0 COG4221@1|root,COG4221@2|Bacteria,1MUF8@1224|Proteobacteria,2TUSA@28211|Alphaproteobacteria,4B809@82115|Rhizobiaceae 28211|Alphaproteobacteria S Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short k141_16678_1 1279017.AQYJ01000027_gene1851 7.65e-237 655.0 COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,1RNCK@1236|Gammaproteobacteria,46527@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - - - - - - - - - - DctP k141_17913_1 345219.Bcoa_0896 1.35e-34 122.0 COG1733@1|root,COG1733@2|Bacteria,1VBI7@1239|Firmicutes,4HKBR@91061|Bacilli,1ZH23@1386|Bacillus 91061|Bacilli K transcriptional yodB GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - - - - - - - - - - HxlR k141_2456_1 1042377.AFPJ01000032_gene2819 1.82e-129 417.0 COG0643@1|root,COG0745@1|root,COG2198@1|root,COG3115@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,COG2198@2|Bacteria,COG3115@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,4650G@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0643 Chemotaxis protein histidine kinase and related kinases chpA - - ko:K02487,ko:K06596 ko02020,ko02025,map02020,map02025 M00507 - - ko00000,ko00001,ko00002,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg k141_10739_1 1453501.JELR01000002_gene609 3.66e-58 187.0 COG1409@1|root,COG1409@2|Bacteria,1MWKX@1224|Proteobacteria,1RPA7@1236|Gammaproteobacteria,466SM@72275|Alteromonadaceae 1236|Gammaproteobacteria S Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes cpdA GO:0003674,GO:0003824,GO:0004112,GO:0004114,GO:0004115,GO:0005488,GO:0005506,GO:0008081,GO:0008150,GO:0008198,GO:0009987,GO:0016043,GO:0016787,GO:0016788,GO:0042545,GO:0042578,GO:0043167,GO:0043169,GO:0045229,GO:0046872,GO:0046914,GO:0071554,GO:0071555,GO:0071840 3.1.4.53 ko:K03651 ko00230,ko02025,map00230,map02025 - R00191 RC00296 ko00000,ko00001,ko01000 - - - Metallophos k141_13308_1 1347368.HG964410_gene7414 3.35e-30 115.0 COG0586@1|root,COG0586@2|Bacteria,1V9H4@1239|Firmicutes,4IQ6W@91061|Bacilli 91061|Bacilli S SNARE associated Golgi protein - - - - - - - - - - - - SNARE_assoc k141_37013_1 218284.CCDN010000006_gene3528 4.21e-132 388.0 COG0619@1|root,COG0619@2|Bacteria,1VBW7@1239|Firmicutes,4HB6S@91061|Bacilli,1ZS19@1386|Bacillus 91061|Bacilli P Spore gernimation protein GerA - - - - - - - - - - - - GerA k141_28791_1 795797.C497_19077 1.91e-12 72.0 COG1109@1|root,arCOG00767@2157|Archaea,2XT1X@28890|Euryarchaeota,23TBN@183963|Halobacteria 183963|Halobacteria G COG1109 Phosphomannomutase pmm4 - 5.4.2.2,5.4.2.8 ko:K15778 ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00114 R00959,R01057,R01818,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV k141_19198_1 218284.CCDN010000005_gene3398 1.74e-158 447.0 COG1801@1|root,COG1801@2|Bacteria,1TPX4@1239|Firmicutes,4HA0X@91061|Bacilli,1ZATP@1386|Bacillus 91061|Bacilli S Protein of unknown function DUF72 yunF - - - - - - - - - - - DUF72 k141_7356_1 1294265.JCM21738_2246 6.35e-182 514.0 COG2081@1|root,COG2081@2|Bacteria,1TQ6E@1239|Firmicutes,4HAAT@91061|Bacilli,1ZAT3@1386|Bacillus 91061|Bacilli S HI0933-like protein ytfP - - ko:K07007 - - - - ko00000 - - - HI0933_like k141_27510_1 674977.VMC_09640 4.6e-149 427.0 COG1344@1|root,COG1344@2|Bacteria,1MV1N@1224|Proteobacteria,1RN0Y@1236|Gammaproteobacteria,1XSDK@135623|Vibrionales 135623|Vibrionales N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella flaD GO:0005575,GO:0005576,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 - - - ko00000,ko00001,ko02035 - - - Flagellin_C,Flagellin_IN,Flagellin_N k141_33476_1 1453501.JELR01000002_gene1152 1.06e-129 382.0 COG2303@1|root,COG2303@2|Bacteria,1MU3F@1224|Proteobacteria,1RPBQ@1236|Gammaproteobacteria,46842@72275|Alteromonadaceae 1236|Gammaproteobacteria E GMC oxidoreductase - - 1.1.5.9 ko:K19813 ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130 - R00305 RC00066 ko00000,ko00001,ko01000 - - - FAD_binding_2,GIDA,GMC_oxred_C,GMC_oxred_N,NAD_binding_8 k141_26421_1 1042377.AFPJ01000024_gene774 5.52e-187 532.0 COG0438@1|root,COG0438@2|Bacteria,1MUTA@1224|Proteobacteria,1RS31@1236|Gammaproteobacteria,465ZQ@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0438 Glycosyltransferase waaG - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 k141_26421_2 1453501.JELR01000002_gene626 2.61e-75 232.0 COG0515@1|root,COG0515@2|Bacteria,1N2QH@1224|Proteobacteria,1SBK8@1236|Gammaproteobacteria,4692P@72275|Alteromonadaceae 1236|Gammaproteobacteria KLT PhoP regulatory network protein YrbL - - - - - - - - - - - - YrbL-PhoP_reg k141_25175_1 441769.ABFU01000037_gene209 4.26e-45 157.0 COG0739@1|root,COG0739@2|Bacteria,1V3ZU@1239|Firmicutes,4I27X@91061|Bacilli,1ZGNS@1386|Bacillus 91061|Bacilli M COG0739 Membrane proteins related to metalloendopeptidases - - - - - - - - - - - - LysM,Peptidase_M23 k141_32228_1 1116375.VEJY3_04580 3.77e-292 807.0 COG2766@1|root,COG2766@2|Bacteria,1MVW7@1224|Proteobacteria,1RNFJ@1236|Gammaproteobacteria,1XT8T@135623|Vibrionales 135623|Vibrionales T Serine protein kinase prkA - - ko:K07180 - - - - ko00000 - - - AAA_PrkA,PrkA k141_32228_2 1116375.VEJY3_04585 4.75e-110 317.0 COG3013@1|root,COG3013@2|Bacteria,1QWV8@1224|Proteobacteria,1RME1@1236|Gammaproteobacteria,1XU0X@135623|Vibrionales 135623|Vibrionales S Belongs to the UPF0304 family yfbU - - ko:K09161 - - - - ko00000 - - - YfbU k141_32228_3 1116375.VEJY3_04590 3.65e-146 413.0 COG3235@1|root,COG3235@2|Bacteria,1RDHR@1224|Proteobacteria,1S90X@1236|Gammaproteobacteria,1XT3Q@135623|Vibrionales 135623|Vibrionales S Cobalt uptake substrate-specific transmembrane region - - - - - - - - - - - - CbiM k141_32228_4 223926.28805979 9.84e-181 502.0 COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria,1RNCR@1236|Gammaproteobacteria,1XUNS@135623|Vibrionales 135623|Vibrionales C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine pflA - 1.97.1.4 ko:K04069 - - R04710 - ko00000,ko01000 - - - Fer4_12,Radical_SAM k141_32228_5 223926.28805980 2.54e-205 571.0 COG3528@1|root,COG3528@2|Bacteria,1QSPH@1224|Proteobacteria,1T09M@1236|Gammaproteobacteria,1Y2YV@135623|Vibrionales 135623|Vibrionales S Uncharacterized protein conserved in bacteria (DUF2219) - - - - - - - - - - - - DUF2219 k141_32228_6 1348635.BBJY01000013_gene1000 0.0 1481.0 COG1882@1|root,COG1882@2|Bacteria,1MWBF@1224|Proteobacteria,1RM96@1236|Gammaproteobacteria,1XT1F@135623|Vibrionales 135623|Vibrionales C COG1882 Pyruvate-formate lyase pflB - 2.3.1.54 ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 - R00212,R06987 RC00004,RC01181,RC02742,RC02833 ko00000,ko00001,ko01000 - - - Gly_radical,PFL-like k141_32228_7 1116375.VEJY3_04610 0.0 967.0 28IWB@1|root,2Z8UK@2|Bacteria,1P3IX@1224|Proteobacteria,1RRBU@1236|Gammaproteobacteria,1XSQK@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF3360) VV2341 - - - - - - - - - - - DUF3360 k141_32228_8 1219077.VAZ01S_016_00640 4.82e-153 452.0 2DJXM@1|root,307SS@2|Bacteria,1RGS8@1224|Proteobacteria,1S4Z9@1236|Gammaproteobacteria,1XZGQ@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_35830_1 218284.CCDN010000002_gene2920 1.55e-127 368.0 COG1090@1|root,COG1090@2|Bacteria,1TRCE@1239|Firmicutes,4HBRT@91061|Bacilli,1ZBKW@1386|Bacillus 91061|Bacilli S nucleoside-diphosphate sugar epimerase yfhF - - ko:K07071 - - - - ko00000 - - - DUF1731,Epimerase k141_6260_3 1325130.HFN_0748 1.52e-07 51.2 COG0756@1|root,COG0756@2|Bacteria,1RA7P@1224|Proteobacteria,42SJS@68525|delta/epsilon subdivisions,2YRU7@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA dut - 3.6.1.23 ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00053 R02100,R11896 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 - - iIT341.HP0865 dUTPase k141_27511_1 1117647.M5M_06505 1.31e-88 282.0 COG1629@1|root,COG4771@2|Bacteria,1MUNK@1224|Proteobacteria,1RN9S@1236|Gammaproteobacteria,1J59B@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_10871_2 1536772.R70723_15830 2.3e-09 60.1 2E36H@1|root,32Y68@2|Bacteria,1VIWS@1239|Firmicutes,4HWRW@91061|Bacilli,26Y90@186822|Paenibacillaceae 91061|Bacilli - - - - - - - - - - - - - - - k141_23968_1 1122919.KB905572_gene3623 7.68e-49 164.0 COG0384@1|root,COG0384@2|Bacteria,1UJBU@1239|Firmicutes,4ITD3@91061|Bacilli,26V97@186822|Paenibacillaceae 91061|Bacilli S phenazine biosynthesis protein PhzF - - - - - - - - - - - - - k141_20355_2 218284.CCDN010000001_gene214 1.27e-15 77.4 COG4325@1|root,COG4325@2|Bacteria,1TSID@1239|Firmicutes,4HDM1@91061|Bacilli,1ZE04@1386|Bacillus 91061|Bacilli S Predicted membrane protein (DUF2254) - - - - - - - - - - - - DUF2254 k141_31173_1 1396418.BATQ01000184_gene2600 1.59e-12 65.1 COG0219@1|root,COG0219@2|Bacteria,46SYZ@74201|Verrucomicrobia,2IUCK@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily - - 2.1.1.207 ko:K03216 - - - - ko00000,ko01000,ko03016 - - - SpoU_methylase k141_2621_1 1279017.AQYJ01000028_gene2137 1.94e-94 300.0 COG0308@1|root,COG0308@2|Bacteria,1PJTM@1224|Proteobacteria,1SYS3@1236|Gammaproteobacteria,4672R@72275|Alteromonadaceae 1236|Gammaproteobacteria E Peptidase family M1 domain - - 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - ERAP1_C,Peptidase_M1 k141_15687_1 1279017.AQYJ01000011_gene3048 1.79e-171 489.0 COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,1RM8U@1236|Gammaproteobacteria,464PJ@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids alr - 5.1.1.1 ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 - R00401 RC00285 ko00000,ko00001,ko01000,ko01011 - - - Ala_racemase_C,Ala_racemase_N k141_15687_2 1042377.AFPJ01000004_gene414 3.83e-93 283.0 COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1MWCC@1224|Proteobacteria,1RNGC@1236|Gammaproteobacteria,465FU@72275|Alteromonadaceae 1236|Gammaproteobacteria K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon birA GO:0000166,GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004077,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009305,GO:0009374,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0017053,GO:0017076,GO:0017144,GO:0018130,GO:0018271,GO:0019538,GO:0019752,GO:0019842,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032991,GO:0033218,GO:0033293,GO:0034641,GO:0035639,GO:0036094,GO:0036211,GO:0042364,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043565,GO:0043603,GO:0043604,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681,GO:1990837 6.3.4.15 ko:K03524 ko00780,ko01100,map00780,map01100 - R01074,R05145 RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko01000,ko03000 - - - BPL_C,BPL_LplA_LipB,HTH_11 k141_3820_1 1048983.EL17_02900 5.2e-07 60.8 COG4797@1|root,COG4797@2|Bacteria,4PKQS@976|Bacteroidetes,47K4H@768503|Cytophagia 976|Bacteroidetes D Motility related/secretion protein sprA - - - - - - - - - - - SprA_N k141_23980_1 1279017.AQYJ01000021_gene2890 6.11e-149 429.0 COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,1RNB6@1236|Gammaproteobacteria,464UG@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate usg GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC k141_23980_2 1195246.AGRI_05437 3.32e-19 96.3 2EBHX@1|root,335IC@2|Bacteria,1NCYG@1224|Proteobacteria,1SFBM@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_23980_3 1453501.JELR01000001_gene1830 9.69e-237 654.0 COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,1RMN3@1236|Gammaproteobacteria,465AH@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate asd GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004073,GO:0006082,GO:0006520,GO:0006549,GO:0006553,GO:0006555,GO:0006566,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009081,GO:0009082,GO:0009085,GO:0009086,GO:0009088,GO:0009089,GO:0009097,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC k141_23980_4 1042377.AFPJ01000037_gene3004 1.8e-226 628.0 COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,1RMZQ@1236|Gammaproteobacteria,465TC@72275|Alteromonadaceae 1236|Gammaproteobacteria CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate leuB GO:0000287,GO:0003674,GO:0003824,GO:0003862,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0030145,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034198,GO:0042594,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114,GO:0071496,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1990928 1.1.1.85 ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R00994,R04426,R10052 RC00084,RC00417,RC03036 br01601,ko00000,ko00001,ko00002,ko01000 - - iECs_1301.ECs0077,iYL1228.KPN_00079,iZ_1308.Z0082 Iso_dh k141_10890_1 1116375.VEJY3_15280 1.45e-200 555.0 COG0408@1|root,COG0408@2|Bacteria,1MWMF@1224|Proteobacteria,1RMM8@1236|Gammaproteobacteria,1XT68@135623|Vibrionales 135623|Vibrionales H Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX hemF GO:0003674,GO:0003824,GO:0004109,GO:0005488,GO:0005515,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0016634,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042802,GO:0042803,GO:0044237,GO:0044249,GO:0044271,GO:0046483,GO:0046983,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.3.3 ko:K00228 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03220 RC00884 ko00000,ko00001,ko00002,ko01000 - - - Coprogen_oxidas k141_10890_2 1116375.VEJY3_15275 5.53e-125 360.0 COG0169@1|root,COG0169@2|Bacteria,1MVH4@1224|Proteobacteria,1RPB7@1236|Gammaproteobacteria,1XTNJ@135623|Vibrionales 135623|Vibrionales E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) aroE GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000 - - - Shikimate_DH,Shikimate_dh_N k141_32239_1 1042377.AFPJ01000004_gene416 5.95e-52 173.0 2E02Y@1|root,32VRV@2|Bacteria,1N1HZ@1224|Proteobacteria,1S93X@1236|Gammaproteobacteria,4688F@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - SPOR k141_28807_1 223926.28805772 5.21e-185 521.0 COG1344@1|root,COG1344@2|Bacteria,1PJUJ@1224|Proteobacteria,1RPNR@1236|Gammaproteobacteria,1XTKN@135623|Vibrionales 135623|Vibrionales N COG1344 Flagellin and related hook-associated proteins flgL - - ko:K02397 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flagellin_C,Flagellin_N k141_28807_2 223926.28805774 7.9e-238 658.0 COG1344@1|root,COG1344@2|Bacteria,1MV1N@1224|Proteobacteria,1RN0Y@1236|Gammaproteobacteria,1XSDK@135623|Vibrionales 135623|Vibrionales N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella flaA GO:0005575,GO:0005576,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 - - - ko00000,ko00001,ko02035 - - - Flagellin_C,Flagellin_IN,Flagellin_N k141_4951_1 218284.CCDN010000007_gene3886 2.87e-32 114.0 COG2261@1|root,COG2261@2|Bacteria,1VENK@1239|Firmicutes,4HNKV@91061|Bacilli,1ZJBG@1386|Bacillus 91061|Bacilli S membrane ydaS - - - - - - - - - - - Transgly_assoc k141_10891_1 1139996.OMQ_00118 1.53e-13 69.7 COG1524@1|root,COG1524@2|Bacteria,1TR0T@1239|Firmicutes,4HD1Y@91061|Bacilli,4B149@81852|Enterococcaceae 91061|Bacilli S Type I phosphodiesterase / nucleotide pyrophosphatase - - - - - - - - - - - - Phosphodiest k141_10891_2 1340434.AXVA01000008_gene3650 3.98e-73 230.0 COG1840@1|root,COG1840@2|Bacteria,1TR2S@1239|Firmicutes,4HC4U@91061|Bacilli,1ZCYV@1386|Bacillus 91061|Bacilli P Bacterial extracellular solute-binding protein - - - ko:K02055 ko02024,map02024 M00193 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11 - - SBP_bac_6 k141_25201_1 1499680.CCFE01000031_gene3726 1.2e-68 225.0 COG3227@1|root,COG3227@2|Bacteria,1TP08@1239|Firmicutes,4H9S6@91061|Bacilli,1ZCEP@1386|Bacillus 91061|Bacilli E Peptidase M4 nprE GO:0005575,GO:0005576 3.4.24.28,3.4.24.30 ko:K01400,ko:K08605 ko02024,map02024 - - - ko00000,ko00001,ko01000,ko01002 - - - FTP,PepSY,Peptidase_M4,Peptidase_M4_C k141_20365_2 218284.CCDN010000007_gene3882 6.58e-42 140.0 2EE71@1|root,3381J@2|Bacteria,1V9B0@1239|Firmicutes,4HJ2A@91061|Bacilli,1ZHAU@1386|Bacillus 91061|Bacilli S gas vesicle protein gvpU - - - - - - - - - - - - k141_7370_1 1279017.AQYJ01000027_gene1938 1.08e-265 737.0 COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,1RNQM@1236|Gammaproteobacteria,463Y4@72275|Alteromonadaceae 1236|Gammaproteobacteria S Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis ubiB GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016020,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901576,GO:1901661,GO:1901663 - ko:K03688 - - - - ko00000 - - iYL1228.KPN_04331 ABC1 k141_7370_3 1453501.JELR01000002_gene1265 3.27e-45 149.0 COG0140@1|root,COG0140@2|Bacteria,1MZEE@1224|Proteobacteria,1S8R4@1236|Gammaproteobacteria,467UR@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0140 Phosphoribosyl-ATP pyrophosphohydrolase hisE GO:0000105,GO:0003674,GO:0003824,GO:0004636,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.6.1.31 ko:K01523 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035 RC00002 ko00000,ko00001,ko00002,ko01000 - - - PRA-PH k141_7370_4 1279017.AQYJ01000027_gene1941 9.79e-31 110.0 COG1826@1|root,COG1826@2|Bacteria,1N6S4@1224|Proteobacteria,1SCC7@1236|Gammaproteobacteria,468CQ@72275|Alteromonadaceae 1236|Gammaproteobacteria U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system tatA GO:0002790,GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009977,GO:0009987,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032940,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - ko:K03116,ko:K03425 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - MttA_Hcf106 k141_7370_5 1279017.AQYJ01000027_gene1942 4.94e-54 177.0 COG1826@1|root,COG1826@2|Bacteria,1N73F@1224|Proteobacteria,1SD9K@1236|Gammaproteobacteria,468EP@72275|Alteromonadaceae 1236|Gammaproteobacteria U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation tatB GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - ko:K03117 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - MttA_Hcf106 k141_7370_6 1279017.AQYJ01000027_gene1943 4.62e-139 397.0 COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,1RPRN@1236|Gammaproteobacteria,4659G@72275|Alteromonadaceae 1236|Gammaproteobacteria U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides tatC GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009314,GO:0009628,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0050896,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - ko:K03118 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - TatC k141_7370_7 1100721.ALKO01000003_gene2256 0.000227 40.8 2DSZH@1|root,33I26@2|Bacteria,1NJQ9@1224|Proteobacteria,2VXPA@28216|Betaproteobacteria,4AG5B@80864|Comamonadaceae 28216|Betaproteobacteria S Protein of unknown function (DUF3149) - - - - - - - - - - - - DUF3149 k141_7370_8 1279017.AQYJ01000025_gene567 3.46e-42 154.0 COG1629@1|root,COG4771@2|Bacteria,1N6JG@1224|Proteobacteria,1RP10@1236|Gammaproteobacteria,465FE@72275|Alteromonadaceae 1236|Gammaproteobacteria P Carboxypeptidase regulatory-like domain - - - - - - - - - - - - CarboxypepD_reg,Plug,TonB_dep_Rec k141_325_2 1279017.AQYJ01000027_gene1579 7.7e-231 639.0 COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,1RMDH@1236|Gammaproteobacteria,46563@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III hemE GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006725,GO:0006778,GO:0006779,GO:0006780,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019353,GO:0019438,GO:0019752,GO:0033013,GO:0033014,GO:0033526,GO:0034641,GO:0042168,GO:0042440,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046394,GO:0046483,GO:0046501,GO:0046502,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 4.1.1.37 ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03197,R04972 RC00872 ko00000,ko00001,ko00002,ko01000 - - iPC815.YPO3734,iSBO_1134.SBO_4018 URO-D k141_18124_2 218284.CCDN010000001_gene1521 2.08e-12 65.1 COG1346@1|root,COG1346@2|Bacteria,1TRGN@1239|Firmicutes,4HF0M@91061|Bacilli,1ZFQ6@1386|Bacillus 91061|Bacilli M effector of murein hydrolase - - - - - - - - - - - - LrgB k141_13332_1 42565.FP66_02010 1.59e-58 191.0 COG1706@1|root,COG1706@2|Bacteria,1MVKW@1224|Proteobacteria,1RMRB@1236|Gammaproteobacteria,1XIS3@135619|Oceanospirillales 135619|Oceanospirillales N Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation flgI - - ko:K02394 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FlgI k141_13332_2 42565.FP66_02005 1.15e-56 184.0 COG1705@1|root,COG3951@1|root,COG1705@2|Bacteria,COG3951@2|Bacteria,1MX2W@1224|Proteobacteria,1RPGY@1236|Gammaproteobacteria,1XI0F@135619|Oceanospirillales 135619|Oceanospirillales MNOU Rod binding protein flgJ - - ko:K02395 - - - - ko00000,ko02035 - - - Glucosaminidase,Rod-binding k141_3840_1 1294265.JCM21738_602 3.77e-124 370.0 COG1388@1|root,COG1388@2|Bacteria,1VETU@1239|Firmicutes,4HP2D@91061|Bacilli,1ZD0H@1386|Bacillus 91061|Bacilli M spore coat assembly protein SafA safA GO:0003674,GO:0005488,GO:0005515,GO:0019899,GO:0051117 - ko:K06370 - - - - ko00000 - - - LysM k141_31187_1 1453501.JELR01000001_gene2683 1.48e-129 377.0 COG1446@1|root,COG1446@2|Bacteria,1MWFC@1224|Proteobacteria,1RNUR@1236|Gammaproteobacteria,465B7@72275|Alteromonadaceae 1236|Gammaproteobacteria E Asparaginase iaaA - 3.4.19.5,3.5.1.1 ko:K01424,ko:K13051 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 - R00485 RC00010,RC02798 ko00000,ko00001,ko01000,ko01002 - - - Asparaginase_2 k141_23981_1 218284.CCDN010000008_gene4160 1.96e-118 343.0 COG0600@1|root,COG0600@2|Bacteria,1TR6A@1239|Firmicutes,4HARB@91061|Bacilli,1ZD96@1386|Bacillus 91061|Bacilli P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component ytlD GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02050 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - BPD_transp_1 k141_23981_2 360911.EAT1b_0745 9.99e-10 59.7 COG0494@1|root,COG0494@2|Bacteria,1V42H@1239|Firmicutes,4HH5W@91061|Bacilli,3WFPX@539002|Bacillales incertae sedis 91061|Bacilli L Belongs to the Nudix hydrolase family ytkD - 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - - NUDIX k141_7371_1 1042377.AFPJ01000037_gene2911 1.08e-35 130.0 COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,1RPGJ@1236|Gammaproteobacteria,4651N@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0436 Aspartate tyrosine aromatic aminotransferase dapC - 2.6.1.17 ko:K14261,ko:K14267 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R04475 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k141_18125_1 935837.JAEK01000067_gene3081 1.63e-84 257.0 COG1175@1|root,COG1175@2|Bacteria,1TRU7@1239|Firmicutes,4HAEJ@91061|Bacilli,1ZDHY@1386|Bacillus 91061|Bacilli G Binding-protein-dependent transport system inner membrane component yurN GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - ko:K10118 ko02010,map02010 M00196 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.28 - - BPD_transp_1 k141_34682_1 586413.CCDL010000001_gene1516 2.1e-40 147.0 COG1164@1|root,COG1164@2|Bacteria,1TPV4@1239|Firmicutes,4HAJJ@91061|Bacilli,23IKP@182709|Oceanobacillus 91061|Bacilli E Oligoendopeptidase F pepF - - - - - - - - - - - Peptidase_M3 k141_34682_2 218284.CCDN010000001_gene215 1.35e-197 553.0 COG3949@1|root,COG3949@2|Bacteria,1U601@1239|Firmicutes,4HBYW@91061|Bacilli,1ZAX1@1386|Bacillus 91061|Bacilli S membrane ykvI - - - - - - - - - - - Spore_permease k141_28808_1 218284.CCDN010000006_gene3772 1.83e-75 238.0 COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TP5X@1239|Firmicutes,4H9KS@91061|Bacilli,1ZE6P@1386|Bacillus 91061|Bacilli G phosphotransferase system ybbF GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563,GO:0090588 2.7.1.211 ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 M00269 R00811 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.1,4.A.1.2.10,4.A.1.2.12,4.A.1.2.9 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC k141_28808_2 218284.CCDN010000006_gene3773 7.47e-26 102.0 COG2103@1|root,COG2103@2|Bacteria,1TPSF@1239|Firmicutes,4HBWP@91061|Bacilli,1ZCFF@1386|Bacillus 91061|Bacilli G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate murQ - 4.2.1.126 ko:K07106 ko00520,ko01100,map00520,map01100 - R08555 RC00397,RC00746 ko00000,ko00001,ko01000 - - - SIS,SIS_2 k141_18126_1 383372.Rcas_3240 1.7e-35 136.0 COG0464@1|root,COG0464@2|Bacteria,2G642@200795|Chloroflexi,374VH@32061|Chloroflexia 32061|Chloroflexia O PFAM AAA ATPase central domain protein - - - - - - - - - - - - AAA k141_25202_1 218284.CCDN010000002_gene2067 8.51e-70 220.0 COG0055@1|root,COG0055@2|Bacteria,1UATS@1239|Firmicutes,4HBRA@91061|Bacilli,1ZDEJ@1386|Bacillus 91061|Bacilli C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits - - 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - HTH_26 k141_23982_1 1294265.JCM21738_4783 8.97e-47 157.0 COG1512@1|root,COG1512@2|Bacteria,1V5YF@1239|Firmicutes,4HK7U@91061|Bacilli,1ZDH4@1386|Bacillus 91061|Bacilli S TPM domain - - - ko:K06872 - - - - ko00000 - - - TPM_phosphatase k141_6290_1 218284.CCDN010000001_gene1966 1.83e-163 461.0 COG1082@1|root,COG1082@2|Bacteria,1TPJT@1239|Firmicutes,4H9KJ@91061|Bacilli,1ZCIZ@1386|Bacillus 91061|Bacilli G Xylose isomerase - - - - - - - - - - - - AP_endonuc_2,AP_endonuc_2_N k141_6290_2 218284.CCDN010000001_gene1967 4.11e-91 275.0 COG0673@1|root,COG0673@2|Bacteria,1TQ72@1239|Firmicutes,4HAGN@91061|Bacilli,1ZCVI@1386|Bacillus 91061|Bacilli S Oxidoreductase family, C-terminal alpha/beta domain - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C k141_3841_1 1121920.AUAU01000001_gene2302 3.63e-74 241.0 COG1875@1|root,COG1875@2|Bacteria,3Y9EQ@57723|Acidobacteria 57723|Acidobacteria T PIN domain - - - - - - - - - - - - PIN_4,PhoH k141_326_1 1279017.AQYJ01000026_gene206 1.07e-108 324.0 COG3735@1|root,COG3735@2|Bacteria,1MVCW@1224|Proteobacteria,1RRI8@1236|Gammaproteobacteria,4659X@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria ybaP - - ko:K09973 - - - - ko00000 - - - TraB k141_9692_2 1294265.JCM21738_1637 2.64e-101 300.0 COG1493@1|root,COG1493@2|Bacteria,1TP5Z@1239|Firmicutes,4HAXR@91061|Bacilli,1ZD05@1386|Bacillus 91061|Bacilli F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion hprK GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K06023 - - - - ko00000,ko01000 - - - Hpr_kinase_C,Hpr_kinase_N k141_18127_1 218284.CCDN010000008_gene4136 2.76e-122 360.0 COG0297@1|root,COG0297@2|Bacteria,1TQ4M@1239|Firmicutes,4HAVA@91061|Bacilli,1ZDBA@1386|Bacillus 91061|Bacilli G Synthesizes alpha-1,4-glucan chains using ADP-glucose glgA GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009011,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 M00565 R02421 RC00005 ko00000,ko00001,ko00002,ko01000,ko01003 - GT5 - Glyco_transf_5,Glycos_transf_1 k141_14509_3 114615.BRADO4388 2.83e-09 62.4 2AAD4@1|root,30ZP1@2|Bacteria,1NBWF@1224|Proteobacteria,2UGDS@28211|Alphaproteobacteria,3K529@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_4952_1 218284.CCDN010000006_gene3617 5.78e-184 517.0 COG2390@1|root,COG2390@2|Bacteria,1TP62@1239|Firmicutes,4HAE6@91061|Bacilli,1ZBYA@1386|Bacillus 91061|Bacilli K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain cggR - - ko:K05311 - - - - ko00000,ko03000 - - - Sugar-bind k141_4952_2 218284.CCDN010000006_gene3616 2.07e-185 519.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,4H9NS@91061|Bacilli,1ZCF9@1386|Bacillus 91061|Bacilli G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family gapA GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042866,GO:0043436,GO:0043891,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N k141_327_1 1294265.JCM21738_2585 4.13e-106 311.0 COG1968@1|root,COG1968@2|Bacteria,1TPFA@1239|Firmicutes,4HCE7@91061|Bacilli,1ZC3Z@1386|Bacillus 91061|Bacilli V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin uppP - 3.6.1.27 ko:K06153 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - BacA k141_7372_1 386456.JQKN01000011_gene782 1.45e-49 191.0 arCOG03439@1|root,arCOG03439@2157|Archaea 2157|Archaea L PFAM periplasmic copper-binding - - - - - - - - - - - - Beta_helix,Big_3_3,NosD,Peptidase_C1 k141_22798_1 674977.VMC_12600 6.71e-264 724.0 COG0741@1|root,COG0741@2|Bacteria,1MW2T@1224|Proteobacteria,1RM9N@1236|Gammaproteobacteria,1XU51@135623|Vibrionales 135623|Vibrionales M Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division mltC - - ko:K08306 - - - - ko00000,ko01000,ko01011 - GH23 - DUF3393,SLT k141_22798_2 55601.VANGNB10_cI0325c 1.73e-60 186.0 COG2924@1|root,COG2924@2|Bacteria,1MZ2V@1224|Proteobacteria,1S964@1236|Gammaproteobacteria,1XXW7@135623|Vibrionales 135623|Vibrionales C Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes yggX - - - - - - - - - - - Iron_traffic k141_22798_3 223926.28807636 1.4e-259 711.0 COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,1RMBT@1236|Gammaproteobacteria,1XTX3@135623|Vibrionales 135623|Vibrionales L COG1194 A G-specific DNA glycosylase mutY - - ko:K03575 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD,NUDIX_4 k141_27620_1 1042377.AFPJ01000010_gene1450 1.66e-96 289.0 COG0589@1|root,COG0589@2|Bacteria,1PAFP@1224|Proteobacteria,1RSCS@1236|Gammaproteobacteria,465CE@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - - - - - - - - - - Usp k141_7497_1 218284.CCDN010000005_gene3247 5.91e-181 517.0 COG0366@1|root,COG0366@2|Bacteria,1TNZ0@1239|Firmicutes,4HB67@91061|Bacilli,1ZAZP@1386|Bacillus 91061|Bacilli G Alpha amylase, N-terminal ig-like domain nplT - 3.2.1.133,3.2.1.135,3.2.1.54 ko:K01208 ko00500,ko01100,map00500,map01100 - R02112,R03122,R11262 - ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,Alpha-amylase_N,Malt_amylase_C k141_32396_2 1453501.JELR01000001_gene3177 8.76e-87 258.0 COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,1S8RG@1236|Gammaproteobacteria,46CRN@72275|Alteromonadaceae 1236|Gammaproteobacteria M OmpA family pal GO:0005575,GO:0005623,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032153,GO:0044425,GO:0044462,GO:0044464,GO:0051301,GO:0071944,GO:0098552 - ko:K03640 - - - - ko00000,ko02000 2.C.1.2 - - OmpA k141_34860_1 288705.RSal33209_0897 2.22e-66 215.0 COG0626@1|root,COG0626@2|Bacteria,2GJ5S@201174|Actinobacteria,1W89J@1268|Micrococcaceae 201174|Actinobacteria E cystathionine metB GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019279,GO:0019343,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071265,GO:0071266,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48 ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017 R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946 RC00020,RC00056,RC00069,RC00420,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv1079 Cys_Met_Meta_PP k141_5176_2 218284.CCDN010000001_gene930 2.25e-52 175.0 COG1459@1|root,COG1459@2|Bacteria,1U00C@1239|Firmicutes,4HGUA@91061|Bacilli,1ZCQK@1386|Bacillus 91061|Bacilli NU COG1459 Type II secretory pathway, component PulF comGB - - ko:K02244 - M00429 - - ko00000,ko00002,ko02044 3.A.14.1 - - T2SSF k141_11133_1 866895.HBHAL_5053 7.44e-63 207.0 COG4146@1|root,COG4146@2|Bacteria,1UHPR@1239|Firmicutes,4HDFI@91061|Bacilli,3NEBU@45667|Halobacillus 91061|Bacilli S Sodium:solute symporter family - - - ko:K03307 - - - - ko00000 2.A.21 - - SSF k141_18309_1 377629.TERTU_4592 1.93e-22 92.4 2CFV6@1|root,32RKG@2|Bacteria,1MZSJ@1224|Proteobacteria,1S9II@1236|Gammaproteobacteria,2PQCH@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria S SpoIIAA-like - - - - - - - - - - - - SpoIIAA-like k141_18309_2 1042377.AFPJ01000043_gene844 0.0 914.0 COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria,464PM@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG1404 Subtilisin-like serine proteases - GO:0005575,GO:0005576 - ko:K14645 ko02024,map02024 - - - ko00000,ko00001,ko01000,ko01002,ko03110 - - - PKD,PPC,P_proprotein,Peptidase_S8 k141_21817_2 218284.CCDN010000006_gene3615 1.83e-123 361.0 COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,4H9R3@91061|Bacilli,1ZCXW@1386|Bacillus 91061|Bacilli F Belongs to the phosphoglycerate kinase family pgk GO:0001871,GO:0002020,GO:0003674,GO:0003824,GO:0004618,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009893,GO:0009986,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019222,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030162,GO:0030193,GO:0030195,GO:0030246,GO:0030247,GO:0030312,GO:0031323,GO:0031325,GO:0032101,GO:0032102,GO:0032268,GO:0032270,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043532,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0045862,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048518,GO:0048519,GO:0048522,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050818,GO:0050819,GO:0050878,GO:0051171,GO:0051173,GO:0051186,GO:0051188,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051917,GO:0051919,GO:0055086,GO:0060255,GO:0061041,GO:0061045,GO:0065007,GO:0065008,GO:0070613,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0080134,GO:0090407,GO:1900046,GO:1900047,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903034,GO:1903035,GO:1903317,GO:1903319,GO:2001065 2.7.2.3 ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01512 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000,ko04147 - - iSB619.SA_RS04145 PGK k141_27621_1 1453501.JELR01000002_gene1524 3.23e-64 217.0 COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,1RNHV@1236|Gammaproteobacteria,46410@72275|Alteromonadaceae 1236|Gammaproteobacteria M Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) mrcB GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008289,GO:0008360,GO:0008658,GO:0008955,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031406,GO:0031975,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042277,GO:0042546,GO:0042597,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071723,GO:0071840,GO:0071944,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 2.4.1.129,3.4.16.4 ko:K05365 ko00550,map00550 - R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 iECIAI39_1322.ECIAI39_0153,iSBO_1134.SBO_0138,iSbBS512_1146.SbBS512_E0140,iYL1228.KPN_00164 PBP1_TM,Transgly,Transpeptidase,UB2H k141_37197_1 1122927.KB895413_gene1570 6.61e-13 70.1 29JNN@1|root,306JZ@2|Bacteria,1TZXS@1239|Firmicutes,4I979@91061|Bacilli,2714C@186822|Paenibacillaceae 91061|Bacilli - - - - - - - - - - - - - - - k141_34861_1 1123284.KB899042_gene1273 6.13e-51 176.0 COG1887@1|root,COG1887@2|Bacteria,1TSTN@1239|Firmicutes,4HBID@91061|Bacilli 91061|Bacilli M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC tagB - 2.7.8.44 ko:K21285 - - R11558 RC00078 ko00000,ko01000 - - iYO844.BSU35760 Glyphos_transf k141_26766_1 218284.CCDN010000001_gene1532 5.28e-227 633.0 COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,4H9ZF@91061|Bacilli,1ZB20@1386|Bacillus 91061|Bacilli C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate glpK GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 - R00847 RC00002,RC00017 ko00000,ko00001,ko01000,ko04147 - - - FGGY_C,FGGY_N k141_26766_2 218284.CCDN010000001_gene1533 1.08e-73 227.0 COG0580@1|root,COG0580@2|Bacteria,1TP4T@1239|Firmicutes,4HAWP@91061|Bacilli,1ZCUB@1386|Bacillus 91061|Bacilli G Belongs to the MIP aquaporin (TC 1.A.8) family glpF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02440 - - - - ko00000,ko02000 1.A.8.1,1.A.8.2 - - MIP k141_8810_1 1116375.VEJY3_17716 8.12e-112 336.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XSE1@135623|Vibrionales 135623|Vibrionales T COG2202 FOG PAS PAC domain - - - ko:K03406,ko:K03776 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - MCPsignal,PAS_3 k141_11134_1 1294265.JCM21738_2798 1.39e-111 342.0 COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,4H9NZ@91061|Bacilli,1ZBJV@1386|Bacillus 91061|Bacilli L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity mutS2 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K07456 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_V,Smr k141_30031_1 1218084.BBJK01000007_gene1003 2.85e-82 276.0 COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,2VKDG@28216|Betaproteobacteria,1K5EP@119060|Burkholderiaceae 28216|Betaproteobacteria G Glycosyl hydrolase 36 superfamily, catalytic domain - - - ko:K13688 - - - - ko00000,ko01000,ko01003 - GH94,GT84 - Glyco_hydro_36,Glyco_transf_36,Glycoamylase k141_7498_1 232346.JHQL01000002_gene979 1.73e-47 164.0 COG1737@1|root,COG1737@2|Bacteria,1R6J5@1224|Proteobacteria,1RQ8A@1236|Gammaproteobacteria,1XKJM@135619|Oceanospirillales 135619|Oceanospirillales K PFAM helix-turn-helix protein RpiR - - - - - - - - - - - - HTH_6,SIS k141_19441_1 1042876.PPS_2625 1e-12 77.0 COG3468@1|root,COG3468@2|Bacteria,1R8WV@1224|Proteobacteria,1S31M@1236|Gammaproteobacteria 1236|Gammaproteobacteria MU Outer membrane autotransporter - - - - - - - - - - - - Autotransporter,Pertactin k141_14637_2 1042377.AFPJ01000030_gene446 2.34e-27 102.0 2E7BZ@1|root,331V9@2|Bacteria,1N8MZ@1224|Proteobacteria 1224|Proteobacteria S Domain of Unknown Function (DUF1540) - - - - - - - - - - - - DUF1540 k141_14637_3 1122137.AQXF01000005_gene1068 3.78e-55 182.0 2BHRH@1|root,32BUY@2|Bacteria,1MZ2C@1224|Proteobacteria,2UM4W@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_26767_1 42565.FP66_10020 1.17e-127 371.0 COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,1RNS6@1236|Gammaproteobacteria,1XHUW@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA kbl - 2.3.1.29 ko:K00639 ko00260,map00260 - R00371 RC00004,RC00394 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 k141_30032_1 880071.Fleli_2790 8.27e-16 82.0 COG1409@1|root,COG1409@2|Bacteria,4P3GR@976|Bacteroidetes 976|Bacteroidetes S Calcineurin-like phosphoesterase - - - - - - - - - - - - Metallophos k141_541_1 218284.CCDN010000010_gene4378 1.65e-68 212.0 COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,4HAK4@91061|Bacilli,1ZB14@1386|Bacillus 91061|Bacilli J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release rplA GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02863 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L1 k141_25422_1 1231057.AMGD01000005_gene2796 4e-39 145.0 2DBJR@1|root,2Z9N7@2|Bacteria,1TRSN@1239|Firmicutes,4HCDI@91061|Bacilli,26EKG@186818|Planococcaceae 91061|Bacilli S Spore germination B3/ GerAC like, C-terminal gerKC - - ko:K06297 - - - - ko00000 - - - Spore_GerAC k141_11135_1 1294265.JCM21738_4176 5.64e-130 380.0 COG0362@1|root,COG0362@2|Bacteria,1TP4I@1239|Firmicutes,4H9NC@91061|Bacilli,1ZC6M@1386|Bacillus 91061|Bacilli G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH gnd - 1.1.1.343,1.1.1.44 ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 M00004,M00006 R01528,R10221 RC00001,RC00539 ko00000,ko00001,ko00002,ko01000 - - - 6PGD,NAD_binding_2 k141_8811_1 218284.CCDN010000005_gene3413 1.24e-124 358.0 COG0647@1|root,COG0647@2|Bacteria,1TQGM@1239|Firmicutes,4HA3R@91061|Bacilli,1ZB73@1386|Bacillus 91061|Bacilli G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro nagD - 3.1.3.41 ko:K01101 ko00627,ko01120,map00627,map01120 - R03024 RC00151 ko00000,ko00001,ko01000 - - - Hydrolase_6,Hydrolase_like k141_12464_1 935836.JAEL01000007_gene2902 4.81e-267 736.0 COG0247@1|root,COG0247@2|Bacteria,1TR46@1239|Firmicutes,4HAY9@91061|Bacilli,1ZATD@1386|Bacillus 91061|Bacilli C Glycolate oxidase glcF - - ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001 - - - CCG,Fer4_8 k141_30040_1 1235279.C772_01775 4.98e-51 165.0 COG2259@1|root,COG2259@2|Bacteria,1VCS2@1239|Firmicutes,4HKRK@91061|Bacilli,26FR1@186818|Planococcaceae 91061|Bacilli S DoxX yfiD1 - - - - - - - - - - - DoxX k141_30040_2 1236976.JCM16418_490 3.77e-53 175.0 COG2514@1|root,COG2514@2|Bacteria,1TPRF@1239|Firmicutes,4HAE7@91061|Bacilli,26RGQ@186822|Paenibacillaceae 91061|Bacilli S Glyoxalase catE - 1.13.11.2 ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 M00569 R00816,R04089,R05295,R05404,R05406,R07795 RC00387,RC00643,RC01075,RC01364,RC01914 ko00000,ko00001,ko00002,ko01000 - - - Glyoxalase k141_25442_3 1117647.M5M_09020 2.82e-108 340.0 COG3118@1|root,COG3118@2|Bacteria,1QWQK@1224|Proteobacteria,1T5NR@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Sulfotransferase domain - - - - - - - - - - - - Sulfotransfer_3 k141_25442_4 1236541.BALL01000029_gene3225 7.92e-14 80.1 COG4773@1|root,COG4773@2|Bacteria,1QTXJ@1224|Proteobacteria,1T2K9@1236|Gammaproteobacteria,2QA73@267890|Shewanellaceae 1236|Gammaproteobacteria P TonB-dependent receptor plug - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_14651_2 1121920.AUAU01000002_gene2089 1.79e-27 110.0 COG0119@1|root,COG0119@2|Bacteria 2|Bacteria E Belongs to the alpha-IPM synthase homocitrate synthase family leuA3 - 2.3.3.13 ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 M00432 R01213 RC00004,RC00470,RC02754 br01601,ko00000,ko00001,ko00002,ko01000 - - - HMGL-like k141_11150_1 1294265.JCM21738_90 2.59e-33 119.0 COG3409@1|root,COG3773@1|root,COG3409@2|Bacteria,COG3773@2|Bacteria,1TRFW@1239|Firmicutes,4HA2V@91061|Bacilli,1ZB40@1386|Bacillus 91061|Bacilli M Spore cortex-lytic enzyme sleB GO:0005575,GO:0005623,GO:0042763,GO:0044464 3.5.1.28 ko:K01449 - - R04112 RC00064,RC00141 ko00000,ko01000 - - - Hydrolase_2,PG_binding_1 k141_7510_1 218284.CCDN010000005_gene3236 1.33e-78 245.0 COG2311@1|root,COG2311@2|Bacteria,1TQNS@1239|Firmicutes,4HCR3@91061|Bacilli,1ZBX3@1386|Bacillus 91061|Bacilli P Protein of unknown function (DUF418) - - - ko:K07148 - - - - ko00000 - - - DUF418 k141_21832_1 391625.PPSIR1_00957 1.27e-72 233.0 COG1611@1|root,COG1611@2|Bacteria,1R7TB@1224|Proteobacteria,43F31@68525|delta/epsilon subdivisions,2X36V@28221|Deltaproteobacteria,2YUKD@29|Myxococcales 28221|Deltaproteobacteria S Belongs to the LOG family - - - - - - - - - - - - - k141_6450_2 1279017.AQYJ01000026_gene351 2.02e-201 563.0 COG2171@1|root,COG2171@2|Bacteria,1MYKK@1224|Proteobacteria,1RM8X@1236|Gammaproteobacteria,46580@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA dapD GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008666,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.117 ko:K00674 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R04365 RC00004,RC01136 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_1530 Hexapep_2,THDPS_M,THDPS_N k141_6450_3 1279017.AQYJ01000026_gene350 3.28e-62 192.0 COG1393@1|root,COG1393@2|Bacteria,1MZ6S@1224|Proteobacteria,1S8TR@1236|Gammaproteobacteria,467VK@72275|Alteromonadaceae 1236|Gammaproteobacteria P Belongs to the ArsC family yffB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.20.4.1 ko:K00537 - - - - ko00000,ko01000 - - - ArsC k141_6450_4 1279017.AQYJ01000026_gene349 3.54e-149 421.0 COG0177@1|root,COG0177@2|Bacteria,1MUYQ@1224|Proteobacteria,1RMHU@1236|Gammaproteobacteria,465DF@72275|Alteromonadaceae 1236|Gammaproteobacteria L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate nth - 4.2.99.18 ko:K10773 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD k141_6450_5 1453501.JELR01000001_gene1930 1.15e-218 610.0 COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,1RPGJ@1236|Gammaproteobacteria,4651N@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0436 Aspartate tyrosine aromatic aminotransferase dapC - 2.6.1.17 ko:K14261,ko:K14267 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R04475 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k141_6450_6 1042377.AFPJ01000037_gene2910 0.0 1465.0 COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,1RN5T@1236|Gammaproteobacteria,464WE@72275|Alteromonadaceae 1236|Gammaproteobacteria O Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen glnD GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008773,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019538,GO:0019752,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0070569,GO:0071704,GO:0140096,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.59 ko:K00990 ko02020,map02020 - - - ko00000,ko00001,ko01000 - - - ACT,GlnD_UR_UTase,HD,NTP_transf_2 k141_6450_8 1042377.AFPJ01000037_gene2908 2.97e-163 458.0 COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,1RN0Z@1236|Gammaproteobacteria,46443@72275|Alteromonadaceae 1236|Gammaproteobacteria J Belongs to the universal ribosomal protein uS2 family rpsB GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02967 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S2 k141_6450_9 1279017.AQYJ01000026_gene343 3.9e-171 481.0 COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,1RPBJ@1236|Gammaproteobacteria,464QB@72275|Alteromonadaceae 1236|Gammaproteobacteria J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome tsf GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005085,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0019899,GO:0034641,GO:0034645,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051020,GO:0065007,GO:0065009,GO:0071704,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02357 - - - - ko00000,ko03012,ko03029 - - - EF_TS k141_6450_11 1279017.AQYJ01000026_gene341 6.64e-108 313.0 COG0233@1|root,COG0233@2|Bacteria,1N66T@1224|Proteobacteria,1RN75@1236|Gammaproteobacteria,466FX@72275|Alteromonadaceae 1236|Gammaproteobacteria J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another frr GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - ko:K02838 - - - - ko00000,ko03012 - - - RRF k141_6450_12 1453501.JELR01000001_gene1937 1.98e-135 388.0 COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,1RMVX@1236|Gammaproteobacteria,4654U@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide uppS GO:0000270,GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006066,GO:0006629,GO:0006720,GO:0006807,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008834,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042546,GO:0043164,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046872,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 ko:K00806 ko00900,ko01110,map00900,map01110 - R06447 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 - - iECBD_1354.ECBD_3445,iECOK1_1307.ECOK1_0175,iECSE_1348.ECSE_0173,iECW_1372.ECW_m0170,iEKO11_1354.EKO11_3744,iEcDH1_1363.EcDH1_3429,iEcE24377_1341.EcE24377A_0178,iEcHS_1320.EcHS_A0176,iNRG857_1313.NRG857_00890,iSFV_1184.SFV_0157,iUMN146_1321.UM146_23675,iUMNK88_1353.UMNK88_178,iWFL_1372.ECW_m0170,iY75_1357.Y75_RS00880 Prenyltransf k141_6450_13 1279017.AQYJ01000026_gene339 4.83e-164 462.0 COG0575@1|root,COG0575@2|Bacteria,1MWSV@1224|Proteobacteria,1RQ6M@1236|Gammaproteobacteria,4651P@72275|Alteromonadaceae 1236|Gammaproteobacteria I Belongs to the CDS family cdsA GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_1596,iSDY_1059.SDY_0191 CTP_transf_1 k141_6450_14 1453501.JELR01000001_gene1939 5.84e-212 595.0 COG0743@1|root,COG0743@2|Bacteria,1MU4G@1224|Proteobacteria,1RNNW@1236|Gammaproteobacteria,464MG@72275|Alteromonadaceae 1236|Gammaproteobacteria I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) dxr GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05688 RC01452 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_1814,iECOK1_1307.ECOK1_0174,iECS88_1305.ECS88_0183,iUMN146_1321.UM146_23670,iUTI89_1310.UTI89_C0188 DXPR_C,DXP_redisom_C,DXP_reductoisom k141_6450_15 1042377.AFPJ01000037_gene2901 1.4e-73 233.0 COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,1RMIX@1236|Gammaproteobacteria,46453@72275|Alteromonadaceae 1236|Gammaproteobacteria M zinc metalloprotease rseP GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016021,GO:0016787,GO:0019219,GO:0019222,GO:0019538,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0043170,GO:0043856,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0045152,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:0140110,GO:1901564,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - ko:K11749 ko02024,ko04112,map02024,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - PDZ,PDZ_2,Peptidase_M50 k141_19449_1 1453501.JELR01000005_gene1676 8.17e-206 590.0 COG0188@1|root,COG0188@2|Bacteria,1MURI@1224|Proteobacteria,1RMTC@1236|Gammaproteobacteria,464Q5@72275|Alteromonadaceae 1236|Gammaproteobacteria L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parC GO:0000819,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006276,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007059,GO:0007062,GO:0008150,GO:0008152,GO:0009330,GO:0009987,GO:0016020,GO:0016043,GO:0019897,GO:0019898,GO:0022402,GO:0030541,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0098813,GO:1901360,GO:1901363 - ko:K02621 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseA_C,DNA_topoisoIV k141_20586_1 891968.Anamo_1341 2.6e-48 171.0 COG0138@1|root,COG0138@2|Bacteria,3T9WS@508458|Synergistetes 508458|Synergistetes F Bifunctional purine biosynthesis protein PurH purH - 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 - - - AICARFT_IMPCHas,MGS k141_20586_2 1122223.KB890688_gene1476 2.73e-29 110.0 COG0299@1|root,COG0299@2|Bacteria,1WMQW@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate purN - 2.1.2.2 ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04325,R04326 RC00026,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 - - - Formyl_trans_N k141_15856_1 666685.R2APBS1_0613 5.72e-22 91.7 COG1309@1|root,COG1309@2|Bacteria,1RCPQ@1224|Proteobacteria,1S1YN@1236|Gammaproteobacteria,1X3K6@135614|Xanthomonadales 135614|Xanthomonadales K transcriptional regulator - - - - - - - - - - - - TetR_N k141_1562_1 1279017.AQYJ01000025_gene570 1.63e-53 168.0 2E3CN@1|root,32YBX@2|Bacteria,1N716@1224|Proteobacteria,1SEFN@1236|Gammaproteobacteria,46C5G@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_12465_1 218284.CCDN010000001_gene732 2.89e-123 358.0 COG1420@1|root,COG1420@2|Bacteria,1TQP7@1239|Firmicutes,4HAX5@91061|Bacilli,1ZBQV@1386|Bacillus 91061|Bacilli K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons hrcA GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K03705 - - - - ko00000,ko03000 - - - HrcA,HrcA_DNA-bdg k141_25443_1 1078085.HMPREF1210_03116 4.39e-62 197.0 COG0789@1|root,COG0789@2|Bacteria,1TS6Z@1239|Firmicutes,4HCVW@91061|Bacilli,26E7W@186818|Planococcaceae 91061|Bacilli K TipAS antibiotic-recognition domain tipA - - - - - - - - - - - MerR_1,TipAS k141_30041_2 118005.AWNK01000005_gene1644 6.21e-06 47.8 COG2863@1|root,COG2863@2|Bacteria 2|Bacteria C cytochrome cccB - - - - - - - - - - - Cytochrom_C,Cytochrome_CBB3 k141_28940_1 218284.CCDN010000005_gene3353 8.57e-119 369.0 COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,4HAFP@91061|Bacilli,1ZBJ3@1386|Bacillus 91061|Bacilli V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran k141_5207_1 218284.CCDN010000003_gene2966 3.53e-200 558.0 COG0470@1|root,COG0470@2|Bacteria,1TRVS@1239|Firmicutes,4HA3T@91061|Bacilli,1ZBDA@1386|Bacillus 91061|Bacilli L DNA polymerase III holB GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576 2.7.7.7 ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNApol3-delta_C k141_32409_1 1279017.AQYJ01000024_gene1031 1.71e-42 144.0 COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,1S41D@1236|Gammaproteobacteria,467B9@72275|Alteromonadaceae 1236|Gammaproteobacteria D COG0424 Nucleotide-binding protein implicated in inhibition of septum formation yhdE GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030145,GO:0036218,GO:0036221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0047429 - ko:K06287 - - - - ko00000 - - - Maf k141_32409_2 1279017.AQYJ01000024_gene1032 0.0 892.0 COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,1RMIW@1236|Gammaproteobacteria,464PN@72275|Alteromonadaceae 1236|Gammaproteobacteria J COG1530 Ribonucleases G and E rng GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005856,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008996,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 - ko:K08301 - - - - ko00000,ko01000,ko03009,ko03019 - - - RNase_E_G,S1 k141_32409_3 1279017.AQYJ01000024_gene1033 3.15e-24 101.0 COG3164@1|root,COG3164@2|Bacteria,1MXWF@1224|Proteobacteria,1RNUK@1236|Gammaproteobacteria,464CY@72275|Alteromonadaceae 1236|Gammaproteobacteria S membrane yhdP GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0042597,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - - - - - - - - - - AsmA_2,DUF3971 k141_24156_1 1042377.AFPJ01000043_gene864 5.25e-09 59.7 COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,1RMQE@1236|Gammaproteobacteria,464C0@72275|Alteromonadaceae 1236|Gammaproteobacteria J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs rnr GO:0000175,GO:0003674,GO:0003724,GO:0003824,GO:0004386,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008408,GO:0008997,GO:0009056,GO:0009057,GO:0009266,GO:0009409,GO:0009628,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016896,GO:0017111,GO:0019222,GO:0019439,GO:0034458,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - ko:K12573 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03016,ko03019 - - - HTH_12,OB_RNB,RNB,S1 k141_557_3 1279017.AQYJ01000028_gene2202 1.54e-84 257.0 COG0515@1|root,COG0515@2|Bacteria,1N2QH@1224|Proteobacteria,1SBK8@1236|Gammaproteobacteria,4692P@72275|Alteromonadaceae 1236|Gammaproteobacteria KLT PhoP regulatory network protein YrbL - - - - - - - - - - - - YrbL-PhoP_reg k141_557_4 357804.Ping_0766 1.99e-132 392.0 COG0662@1|root,COG0836@1|root,COG0662@2|Bacteria,COG0836@2|Bacteria,1MV39@1224|Proteobacteria,1RNQI@1236|Gammaproteobacteria,2QIS8@267894|Psychromonadaceae 1236|Gammaproteobacteria M Mannose-6-phosphate isomerase cpsB - 2.7.7.13,5.3.1.8 ko:K00971,ko:K16011 ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025 M00114,M00361,M00362 R00885,R01819 RC00002,RC00376 ko00000,ko00001,ko00002,ko01000 - - - MannoseP_isomer,NTP_transferase k141_13631_1 1279017.AQYJ01000027_gene1798 3.2e-71 226.0 COG1195@1|root,COG1195@2|Bacteria,1MX8N@1224|Proteobacteria,1RN5P@1236|Gammaproteobacteria,466CC@72275|Alteromonadaceae 1236|Gammaproteobacteria L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP recF GO:0000731,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0018130,GO:0019438,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - ko:K03629 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - SMC_N k141_6451_1 1294265.JCM21738_3521 1.68e-127 383.0 COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,4HB12@91061|Bacilli,1ZCM9@1386|Bacillus 91061|Bacilli L ATP-dependent DNA helicase pcrA - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C k141_1563_1 218284.CCDN010000005_gene3452 7.35e-152 435.0 COG0477@1|root,COG2814@2|Bacteria,1TRDJ@1239|Firmicutes,4H9Q9@91061|Bacilli,1ZBN7@1386|Bacillus 91061|Bacilli EGP Major facilitator superfamily yuxJ - - - - - - - - - - - MFS_1,Sugar_tr k141_15857_1 218284.CCDN010000002_gene2216 1.45e-158 452.0 COG2309@1|root,COG2309@2|Bacteria,1TP65@1239|Firmicutes,4H9W8@91061|Bacilli,1ZCU3@1386|Bacillus 91061|Bacilli E COG2309 Leucyl aminopeptidase (aminopeptidase T) ampS - - ko:K19689 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M29 k141_20588_1 218284.CCDN010000001_gene1775 5.19e-72 241.0 COG0419@1|root,COG0419@2|Bacteria,1TPCS@1239|Firmicutes,4H9Q3@91061|Bacilli,1ZAP5@1386|Bacillus 91061|Bacilli L COG0419 ATPase involved in DNA repair sbcC - - ko:K03546 - - - - ko00000,ko03400 - - - AAA_23,AAA_29,SbcCD_C k141_33752_1 1116375.VEJY3_04365 4.33e-176 499.0 COG2723@1|root,COG2723@2|Bacteria,1MWG6@1224|Proteobacteria,1RMM2@1236|Gammaproteobacteria,1XSV6@135623|Vibrionales 135623|Vibrionales G Belongs to the glycosyl hydrolase 1 family - - 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 - R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 - GT1 - Glyco_hydro_1 k141_11153_1 1453501.JELR01000001_gene2975 2.6e-194 562.0 COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,1RP14@1236|Gammaproteobacteria,464DK@72275|Alteromonadaceae 1236|Gammaproteobacteria J Belongs to the class-I aminoacyl-tRNA synthetase family leuS GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - iECOK1_1307.ECOK1_0652,iECS88_1305.ECS88_0684,iNRG857_1313.NRG857_02925,iPC815.YPO2610 Anticodon_1,tRNA-synt_1,tRNA-synt_1_2 k141_558_1 218284.CCDN010000001_gene997 2.76e-50 162.0 COG1376@1|root,COG1376@2|Bacteria,1V26F@1239|Firmicutes,4HG56@91061|Bacilli,1ZGC7@1386|Bacillus 91061|Bacilli S protein conserved in bacteria yqjB - - - - - - - - - - - YkuD k141_25446_1 1195246.AGRI_06735 1.97e-29 123.0 COG1629@1|root,COG4206@1|root,COG4206@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria,464NB@72275|Alteromonadaceae 1236|Gammaproteobacteria P Outer membrane receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_21834_1 42565.FP66_06465 1.64e-167 506.0 COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,1RPYH@1236|Gammaproteobacteria,1XH56@135619|Oceanospirillales 135619|Oceanospirillales K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoC - 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 k141_32410_1 1042377.AFPJ01000024_gene774 9.24e-109 325.0 COG0438@1|root,COG0438@2|Bacteria,1MUTA@1224|Proteobacteria,1RS31@1236|Gammaproteobacteria,465ZQ@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0438 Glycosyltransferase waaG - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 k141_20589_1 42565.FP66_00665 1.27e-71 228.0 COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,1RMKV@1236|Gammaproteobacteria,1XH83@135619|Oceanospirillales 135619|Oceanospirillales E Amino acid permease - - - - - - - - - - - - AA_permease_2 k141_9976_1 223926.28806928 1.03e-57 179.0 COG0633@1|root,COG0633@2|Bacteria,1QU91@1224|Proteobacteria,1T1VI@1236|Gammaproteobacteria,1XXYP@135623|Vibrionales 135623|Vibrionales C COG0633 Ferredoxin - - - ko:K11107 - - - - ko00000 - - - Fer2 k141_9976_2 1280001.BAOA01000128_gene1202 5.6e-271 741.0 COG0208@1|root,COG0208@2|Bacteria,1MWUS@1224|Proteobacteria,1RMJC@1236|Gammaproteobacteria,1XSHZ@135623|Vibrionales 135623|Vibrionales F COG0208 Ribonucleotide reductase, beta subunit nrdB - 1.17.4.1 ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_sm k141_9976_3 1116375.VEJY3_10135 0.0 1484.0 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,1RMPV@1236|Gammaproteobacteria,1XTXI@135623|Vibrionales 135623|Vibrionales F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdA - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN k141_9976_4 223926.28806925 3.54e-164 459.0 COG2227@1|root,COG2227@2|Bacteria,1MU89@1224|Proteobacteria,1RMV7@1236|Gammaproteobacteria,1XSEV@135623|Vibrionales 135623|Vibrionales H O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway ubiG GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008689,GO:0008757,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0061542,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.1.1.222,2.1.1.64 ko:K00568 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04988,R05614,R08769,R08781 RC00003,RC00392,RC01895 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_23 k141_9976_5 223926.28806924 0.0 1385.0 COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,1RN03@1236|Gammaproteobacteria,1XSUD@135623|Vibrionales 135623|Vibrionales L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrA - 5.99.1.3 ko:K02469 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseA_C,DNA_topoisoIV k141_9976_6 223926.28806913 8.16e-97 284.0 COG0807@1|root,COG0807@2|Bacteria,1MWZR@1224|Proteobacteria,1RMFX@1236|Gammaproteobacteria,1XU21@135623|Vibrionales 135623|Vibrionales F Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate ribA GO:0003674,GO:0003824,GO:0003933,GO:0003935,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019238,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.5.4.25 ko:K01497 ko00740,ko00790,ko01100,ko01110,ko02024,map00740,map00790,map01100,map01110,map02024 M00125 R00425 RC00293,RC02504 ko00000,ko00001,ko00002,ko01000 - - - GTP_cyclohydro2 k141_24157_1 218284.CCDN010000008_gene4177 5.62e-180 504.0 COG1242@1|root,COG1242@2|Bacteria,1TQ57@1239|Firmicutes,4H9N8@91061|Bacilli,1ZBM1@1386|Bacillus 91061|Bacilli S Fe-S oxidoreductase ytqA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K07139 - - - - ko00000 - - - Radical_SAM,Radical_SAM_C k141_11154_1 218284.CCDN010000002_gene2070 5.6e-27 109.0 COG1199@1|root,COG1199@2|Bacteria,1TPNB@1239|Firmicutes,4HD6T@91061|Bacilli,1ZAUN@1386|Bacillus 91061|Bacilli KL DEAD_2 uvrB3 - 3.1.12.1 ko:K07464 - - - - ko00000,ko01000,ko02048 - - - DEAD,DEAD_2,HBB,Helicase_C_2,PDDEXK_1 k141_31403_2 1279017.AQYJ01000027_gene1941 1.9e-30 110.0 COG1826@1|root,COG1826@2|Bacteria,1N6S4@1224|Proteobacteria,1SCC7@1236|Gammaproteobacteria,468CQ@72275|Alteromonadaceae 1236|Gammaproteobacteria U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system tatA GO:0002790,GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009977,GO:0009987,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032940,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - ko:K03116,ko:K03425 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - MttA_Hcf106 k141_31403_3 1279017.AQYJ01000027_gene1942 4.47e-49 164.0 COG1826@1|root,COG1826@2|Bacteria,1N73F@1224|Proteobacteria,1SD9K@1236|Gammaproteobacteria,468EP@72275|Alteromonadaceae 1236|Gammaproteobacteria U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation tatB GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - ko:K03117 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - MttA_Hcf106 k141_31403_5 1453501.JELR01000002_gene1269 3.37e-81 252.0 COG1075@1|root,COG1075@2|Bacteria,1N2W0@1224|Proteobacteria,1S2JW@1236|Gammaproteobacteria,46749@72275|Alteromonadaceae 1236|Gammaproteobacteria S acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - - - - - - - - - - Abhydrolase_6,DUF676,Hydrolase_4,PGAP1 k141_786_1 197221.22295556 1.34e-29 118.0 COG1611@1|root,COG1611@2|Bacteria,1G0JD@1117|Cyanobacteria 1117|Cyanobacteria S Rossmann fold nucleotide-binding protein - - 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - Lysine_decarbox k141_22030_2 1279017.AQYJ01000023_gene3257 8.49e-149 422.0 COG1028@1|root,COG1028@2|Bacteria,1MUBQ@1224|Proteobacteria,1RQJT@1236|Gammaproteobacteria,465UP@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) fabG - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short,adh_short_C2 k141_22030_3 1453501.JELR01000006_gene7 2.08e-181 513.0 COG3137@1|root,COG3137@2|Bacteria,1RHDT@1224|Proteobacteria,1S1K4@1236|Gammaproteobacteria,467CN@72275|Alteromonadaceae 1236|Gammaproteobacteria M Protein of unknown function, DUF481 - - - - - - - - - - - - DUF481 k141_22030_4 498211.CJA_2651 4.66e-34 120.0 COG3695@1|root,COG3695@2|Bacteria,1N7J2@1224|Proteobacteria,1SCIZ@1236|Gammaproteobacteria,1FHIZ@10|Cellvibrio 1236|Gammaproteobacteria L 6-O-methylguanine DNA methyltransferase, DNA binding domain ybaZ GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0005488,GO:0005515,GO:0019899,GO:0097159,GO:1901363 - ko:K07443 - - - - ko00000 - - - DNA_binding_1 k141_22030_5 1453501.JELR01000006_gene8 6.47e-257 712.0 COG0477@1|root,COG2814@2|Bacteria,1MUZ8@1224|Proteobacteria,1T1NH@1236|Gammaproteobacteria,46DC9@72275|Alteromonadaceae 1236|Gammaproteobacteria EGP Acetyl-coenzyme A transporter 1 ampG GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015672,GO:0015835,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1901264,GO:1902600 - ko:K08218 ko01501,map01501 M00628 - - ko00000,ko00001,ko00002,ko02000 2.A.1.25 - - MFS_1 k141_22030_6 1279017.AQYJ01000023_gene3252 5.95e-98 289.0 COG1881@1|root,COG1881@2|Bacteria,1N0Y4@1224|Proteobacteria,1S400@1236|Gammaproteobacteria,466X5@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG1881 Phospholipid-binding protein ybhB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K06910 - - - - ko00000 - - - PBP k141_22030_7 1279017.AQYJ01000023_gene3251 4.87e-172 487.0 COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,1RPGU@1236|Gammaproteobacteria,46519@72275|Alteromonadaceae 1236|Gammaproteobacteria E Threonine dehydratase tdcB - 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - - PALP k141_22030_8 1279017.AQYJ01000023_gene3250 1.49e-60 199.0 COG1012@1|root,COG1012@2|Bacteria,1MVGW@1224|Proteobacteria,1RN53@1236|Gammaproteobacteria,4656Y@72275|Alteromonadaceae 1236|Gammaproteobacteria C belongs to the aldehyde dehydrogenase family ywdH - 1.2.1.3 ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_30218_1 1116375.VEJY3_24336 1.19e-128 385.0 COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1MUQV@1224|Proteobacteria,1RN0Q@1236|Gammaproteobacteria,1XU7X@135623|Vibrionales 135623|Vibrionales T COG2199 FOG GGDEF domain VVA1653 - - - - - - - - - - - EAL,GGDEF,HAMP,LapD_MoxY_N k141_6626_2 1453501.JELR01000005_gene1732 4.76e-65 198.0 COG0198@1|root,COG0198@2|Bacteria,1MZQD@1224|Proteobacteria,1S973@1236|Gammaproteobacteria,467RK@72275|Alteromonadaceae 1236|Gammaproteobacteria J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit rplX GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02895 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KOW,ribosomal_L24 k141_29126_1 218284.CCDN010000001_gene96 1.59e-26 105.0 COG1893@1|root,COG1893@2|Bacteria,1V1NJ@1239|Firmicutes,4HFWT@91061|Bacilli,1ZFJY@1386|Bacillus 91061|Bacilli H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid panE GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008677,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU15110 ApbA,ApbA_C k141_29126_2 218284.CCDN010000001_gene97 7.96e-60 197.0 COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,4HBK9@91061|Bacilli,1ZBHM@1386|Bacillus 91061|Bacilli I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) yngE - - - - - - - - - - iYO844.BSU18210 Carboxyl_trans k141_35188_1 218284.CCDN010000004_gene3078 2.21e-93 293.0 COG3973@1|root,COG3973@2|Bacteria,1TP39@1239|Firmicutes,4H9Y5@91061|Bacilli,1ZAWP@1386|Bacillus 91061|Bacilli L DNA helicase helD_2 - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_19,UvrD-helicase,UvrD_C,UvrD_C_2 k141_24433_1 1294265.JCM21738_2257 2.61e-105 310.0 COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,4HAMU@91061|Bacilli,1ZC73@1386|Bacillus 91061|Bacilli E Belongs to the cysteine synthase cystathionine beta- synthase family ytkP GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03601,R04859 RC00020,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 - - - PALP k141_37394_1 1453498.LG45_05180 1.49e-15 73.9 COG1764@1|root,COG1764@2|Bacteria,4PK2I@976|Bacteroidetes,1I3KT@117743|Flavobacteriia,2NX49@237|Flavobacterium 976|Bacteroidetes O OsmC-like protein - - - - - - - - - - - - OsmC k141_37394_2 1042377.AFPJ01000007_gene1878 3.16e-80 245.0 COG2866@1|root,COG2866@2|Bacteria,1MYRD@1224|Proteobacteria,1T1MH@1236|Gammaproteobacteria,46D94@72275|Alteromonadaceae 1236|Gammaproteobacteria E Succinylglutamate desuccinylase / Aspartoacylase family XCC2022 - - - - - - - - - - - AstE_AspA,DUF2817,Peptidase_M14 k141_19726_1 1219076.N646_2211 5.61e-114 329.0 COG1739@1|root,COG1739@2|Bacteria,1NFJC@1224|Proteobacteria,1RPBF@1236|Gammaproteobacteria,1XTYV@135623|Vibrionales 135623|Vibrionales S Domain of unknown function (DUF1949) yigZ - - - - - - - - - - - DUF1949,UPF0029 k141_19726_2 1116375.VEJY3_00150 0.0 948.0 COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,1RMN6@1236|Gammaproteobacteria,1XU4M@135623|Vibrionales 135623|Vibrionales P Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA trkH GO:0003674,GO:0005215,GO:0005216,GO:0005261,GO:0005267,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015318,GO:0015672,GO:0016020,GO:0016021,GO:0022803,GO:0022838,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031224,GO:0031226,GO:0031420,GO:0034220,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0046983,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098660,GO:0098662 - ko:K03498 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkH k141_19726_3 1116375.VEJY3_00155 3.3e-119 341.0 COG4635@1|root,COG4635@2|Bacteria,1RAH2@1224|Proteobacteria,1S372@1236|Gammaproteobacteria,1XSWA@135623|Vibrionales 135623|Vibrionales CH protoporphyrinogen oxidase hemG - 1.3.5.3 ko:K00230 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R09489 RC00885 ko00000,ko00001,ko00002,ko01000 - - - Flavodoxin_5 k141_36200_1 218284.CCDN010000001_gene951 2.59e-121 353.0 COG0006@1|root,COG0006@2|Bacteria,1TQ44@1239|Firmicutes,4HAT7@91061|Bacilli,1ZB4P@1386|Bacillus 91061|Bacilli E COG0006 Xaa-Pro aminopeptidase yqhT - 3.4.11.9,3.4.13.9 ko:K01262,ko:K01271 - - - - ko00000,ko01000,ko01002 - - - Creatinase_N,Peptidase_M24 k141_27052_1 218284.CCDN010000001_gene157 1.65e-112 325.0 COG0242@1|root,COG0242@2|Bacteria,1V70B@1239|Firmicutes,4HH0G@91061|Bacilli,1ZB0K@1386|Bacillus 91061|Bacilli J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions def GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 ko:K01462 - - - - ko00000,ko01000 - - - Pep_deformylase k141_18611_1 1453501.JELR01000002_gene386 3.78e-159 459.0 COG2223@1|root,COG2223@2|Bacteria,1MU27@1224|Proteobacteria,1RP5H@1236|Gammaproteobacteria,4651E@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG2223 Nitrate nitrite transporter - - - ko:K02575 ko00910,map00910 M00615 - - ko00000,ko00001,ko00002,ko02000 2.A.1.8 - - MFS_1 k141_27825_2 218284.CCDN010000008_gene4143 2.28e-136 402.0 COG1165@1|root,COG1165@2|Bacteria,1TRDB@1239|Firmicutes,4HC48@91061|Bacilli,1ZANU@1386|Bacillus 91061|Bacilli H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) menD - 2.2.1.9 ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R08165 RC02186 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS05085 TPP_enzyme_C,TPP_enzyme_M_2,TPP_enzyme_N k141_5523_1 218284.CCDN010000001_gene41 6.48e-83 266.0 COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,4H9KD@91061|Bacilli,1ZBBU@1386|Bacillus 91061|Bacilli KLT serine threonine protein kinase prkC GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 ko:K08884,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PASTA,Pkinase k141_16087_1 1042377.AFPJ01000052_gene1540 1.61e-155 454.0 COG2148@1|root,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,1RMMN@1236|Gammaproteobacteria,46597@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG2148 Sugar transferases involved in lipopolysaccharide synthesis wcaJ - - ko:K03606 ko05111,map05111 - - - ko00000,ko00001 - - - Bac_transf,CoA_binding_3 k141_27053_1 314275.MADE_1020480 9.85e-39 129.0 COG0636@1|root,32S3K@2|Bacteria,1N1NA@1224|Proteobacteria,1S9MD@1236|Gammaproteobacteria,468H6@72275|Alteromonadaceae 1236|Gammaproteobacteria C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpE GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_C k141_27053_2 425104.Ssed_4490 2.11e-25 97.8 COG0711@1|root,COG0711@2|Bacteria,1RHZ0@1224|Proteobacteria,1S402@1236|Gammaproteobacteria,2QADG@267890|Shewanellaceae 1236|Gammaproteobacteria C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpF GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031225,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - e_coli_core.b3736,iAF1260.b3736,iB21_1397.B21_03564,iBWG_1329.BWG_3427,iE2348C_1286.E2348C_4046,iEC042_1314.EC042_4123,iEC55989_1330.EC55989_4211,iECABU_c1320.ECABU_c42210,iECBD_1354.ECBD_4296,iECB_1328.ECB_03620,iECDH10B_1368.ECDH10B_3923,iECDH1ME8569_1439.ECDH1ME8569_3624,iECD_1391.ECD_03620,iECED1_1282.ECED1_4426,iECH74115_1262.ECH74115_5172,iECIAI1_1343.ECIAI1_3920,iECIAI39_1322.ECIAI39_4340,iECO103_1326.ECO103_4422,iECO111_1330.ECO111_4570,iECO26_1355.ECO26_4842,iECOK1_1307.ECOK1_4185,iECP_1309.ECP_3935,iECS88_1305.ECS88_4158,iECSE_1348.ECSE_4026,iECSF_1327.ECSF_3584,iECSP_1301.ECSP_4786,iECUMN_1333.ECUMN_4266,iECW_1372.ECW_m4039,iECs_1301.ECs4678,iEKO11_1354.EKO11_4609,iETEC_1333.ETEC_4027,iEcDH1_1363.EcDH1_4231,iEcE24377_1341.EcE24377A_4252,iEcHS_1320.EcHS_A3952,iEcSMS35_1347.EcSMS35_4104,iEcolC_1368.EcolC_4258,iG2583_1286.G2583_4532,iJO1366.b3736,iJR904.b3736,iSDY_1059.SDY_4012,iSFV_1184.SFV_3762,iSF_1195.SF3816,iSFxv_1172.SFxv_4159,iSSON_1240.SSON_3883,iS_1188.S3952,iSbBS512_1146.SbBS512_E4185,iUMN146_1321.UM146_18870,iUMNK88_1353.UMNK88_4548,iUTI89_1310.UTI89_C4291,iWFL_1372.ECW_m4039,iY75_1357.Y75_RS18390,iZ_1308.Z5234,ic_1306.c4664 ATP-synt_B k141_18612_1 1348908.KI518590_gene2734 6.09e-24 103.0 29SI9@1|root,30DPE@2|Bacteria,1UBHF@1239|Firmicutes,4IMWS@91061|Bacilli,1ZM1M@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_37395_2 398720.MED217_17845 2.2e-52 176.0 COG1533@1|root,COG1533@2|Bacteria,4NE62@976|Bacteroidetes,1HYJS@117743|Flavobacteriia,2XIYR@283735|Leeuwenhoekiella 976|Bacteroidetes L Elongator protein 3, MiaB family, Radical SAM - - - - - - - - - - - - Radical_SAM k141_32620_1 42565.FP66_13530 3.14e-108 320.0 COG2021@1|root,COG2021@2|Bacteria,1MVJV@1224|Proteobacteria,1RQ2N@1236|Gammaproteobacteria,1XHTS@135619|Oceanospirillales 135619|Oceanospirillales E Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine metX - 2.3.1.31 ko:K00641 ko00270,ko01100,ko01130,map00270,map01100,map01130 - R01776 RC00004,RC00041 ko00000,ko00001,ko01000 - - - Abhydrolase_1 k141_10325_2 218284.CCDN010000006_gene3511 1.34e-127 367.0 COG0300@1|root,COG0300@2|Bacteria,1UZHA@1239|Firmicutes,4HA3H@91061|Bacilli,1ZCKZ@1386|Bacillus 91061|Bacilli S Enoyl-(Acyl carrier protein) reductase - - - ko:K07124 - - - - ko00000 - - - adh_short k141_5524_1 218284.CCDN010000002_gene2855 4.81e-91 298.0 COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1TQ0B@1239|Firmicutes,4HA4G@91061|Bacilli,1ZBFF@1386|Bacillus 91061|Bacilli E glutamate synthase gltA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14,1.4.7.1 ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 - R00021,R00093,R00114,R00248,R10086 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - GATase_2,GXGXG,Glu_syn_central,Glu_synthase k141_12734_1 246197.MXAN_6811 1.69e-61 216.0 COG1505@1|root,COG1505@2|Bacteria,1NZ7N@1224|Proteobacteria,42NR5@68525|delta/epsilon subdivisions,2WMMK@28221|Deltaproteobacteria,2YU26@29|Myxococcales 28221|Deltaproteobacteria E Prolyl oligopeptidase, N-terminal beta-propeller domain - - 3.4.21.26 ko:K01322 ko04614,map04614 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S9,Peptidase_S9_N k141_36201_1 324057.Pjdr2_4516 1.48e-56 187.0 COG0053@1|root,COG0053@2|Bacteria,1TSGY@1239|Firmicutes,4H9WP@91061|Bacilli,26QPC@186822|Paenibacillaceae 91061|Bacilli P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family yeaB - - - - - - - - - - - Cation_efflux,ZT_dimer k141_35190_1 218284.CCDN010000007_gene3814 1.24e-172 497.0 COG3887@1|root,COG3887@2|Bacteria,1TPGP@1239|Firmicutes,4HBVH@91061|Bacilli,1ZCB0@1386|Bacillus 91061|Bacilli T signaling protein consisting of a modified GGDEF domain and a DHH domain yybT - - - - - - - - - - - DHH,DHHA1 k141_29127_1 218284.CCDN010000001_gene489 8.9e-58 183.0 COG1595@1|root,COG1595@2|Bacteria,1UV24@1239|Firmicutes,4I56D@91061|Bacilli,1ZNWB@1386|Bacillus 91061|Bacilli K Sigma-70, region 4 - - - - - - - - - - - - - k141_19727_1 1042377.AFPJ01000024_gene724 9.96e-75 233.0 COG0687@1|root,COG0687@2|Bacteria,1MUYW@1224|Proteobacteria,1RM7W@1236|Gammaproteobacteria,4654B@72275|Alteromonadaceae 1236|Gammaproteobacteria E Required for the activity of the bacterial periplasmic transport system of putrescine potF - - ko:K11073 ko02010,map02010 M00300 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.2 - - SBP_bac_6,SBP_bac_8 k141_19727_2 1453501.JELR01000002_gene547 6.06e-10 58.9 COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,1RMHQ@1236|Gammaproteobacteria,4641N@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism glyA GO:0001505,GO:0003674,GO:0003824,GO:0004372,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006546,GO:0006563,GO:0006565,GO:0006730,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009069,GO:0009070,GO:0009071,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016741,GO:0016742,GO:0017144,GO:0019264,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042133,GO:0042135,GO:0042136,GO:0042737,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0065007,GO:0065008,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 - - iG2583_1286.G2583_3081 SHMT k141_2943_1 1294265.JCM21738_2033 6.06e-10 58.9 COG0840@1|root,COG0840@2|Bacteria,1V0SD@1239|Firmicutes,4HD8P@91061|Bacilli,1ZCT0@1386|Bacillus 91061|Bacilli NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - - - - - - - - - - MCPsignal k141_2943_2 1294265.JCM21738_2034 5.99e-109 315.0 29WYG@1|root,30IKQ@2|Bacteria,1V4Y2@1239|Firmicutes,4HI5K@91061|Bacilli,1ZHEH@1386|Bacillus 91061|Bacilli S SpoIIIAH-like protein spoIIIAH - - ko:K06397 - - - - ko00000 1.A.34.1.1 - - SpoIIIAH k141_2943_3 1294265.JCM21738_2035 5.56e-50 163.0 2E6BB@1|root,330Z5@2|Bacteria,1VF3M@1239|Firmicutes,4HH7J@91061|Bacilli,1ZEMQ@1386|Bacillus 91061|Bacilli S stage III sporulation protein AG spoIIIAG - - ko:K06396 - - - - ko00000 - - - - k141_5525_1 218284.CCDN010000002_gene2212 2.36e-101 310.0 COG4146@1|root,COG4146@2|Bacteria,1UHPR@1239|Firmicutes,4HDFI@91061|Bacilli,1ZDJB@1386|Bacillus 91061|Bacilli S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - ko:K03307 - - - - ko00000 2.A.21 - - SSF k141_18613_2 218284.CCDN010000005_gene3419 9.32e-53 176.0 COG2124@1|root,COG2124@2|Bacteria,1TPWZ@1239|Firmicutes,4HAGS@91061|Bacilli,1ZC1Y@1386|Bacillus 91061|Bacilli C Cytochrome P450 cypA - - ko:K15468 - - - - ko00000,ko01008 - - - p450 k141_6628_1 1453501.JELR01000002_gene1345 2.03e-113 335.0 COG2961@1|root,COG2961@2|Bacteria,1MWGA@1224|Proteobacteria,1RNI1@1236|Gammaproteobacteria,466GS@72275|Alteromonadaceae 1236|Gammaproteobacteria S Specifically methylates the adenine in position 2030 of 23S rRNA rlmJ GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008988,GO:0009451,GO:0009987,GO:0010467,GO:0015976,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036307,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.266 ko:K07115 - - - - ko00000,ko01000,ko03009 - - - RsmJ k141_37397_1 218284.CCDN010000002_gene2921 2.21e-90 270.0 COG2137@1|root,COG2137@2|Bacteria,1V72V@1239|Firmicutes,4HJ7R@91061|Bacilli,1ZC8N@1386|Bacillus 91061|Bacilli S Modulates RecA activity recX - - ko:K03565 - - - - ko00000,ko03400 - - - RecX k141_37397_2 218284.CCDN010000002_gene2922 2.85e-18 79.0 29NVC@1|root,309TF@2|Bacteria,1U5NJ@1239|Firmicutes,4IFD5@91061|Bacilli,1ZKA7@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_24435_1 1116375.VEJY3_22981 1.23e-182 508.0 COG2207@1|root,COG2207@2|Bacteria,1NETZ@1224|Proteobacteria,1RRXN@1236|Gammaproteobacteria,1XSYH@135623|Vibrionales 135623|Vibrionales K Transcriptional regulator - - - - - - - - - - - - AraC_binding,HTH_18 k141_30220_2 1183438.GKIL_3929 1e-16 82.8 COG1228@1|root,COG1228@2|Bacteria,1G3PN@1117|Cyanobacteria 1117|Cyanobacteria Q Amidohydrolase family - - - - - - - - - - - - Amidohydro_1 k141_27826_3 1279017.AQYJ01000028_gene2349 1.38e-45 150.0 COG4633@1|root,COG4633@2|Bacteria,1N1UQ@1224|Proteobacteria,1S9HX@1236|Gammaproteobacteria,467WZ@72275|Alteromonadaceae 1236|Gammaproteobacteria S Cupredoxin-like domain - - - - - - - - - - - - Cupredoxin_1 k141_18614_1 218284.CCDN010000002_gene2756 1.03e-116 337.0 COG1309@1|root,COG1309@2|Bacteria 2|Bacteria K transcriptional regulator - - - - - - - - - - - - TetR_N k141_2944_1 251229.Chro_1068 9.91e-34 129.0 COG1503@1|root,COG1503@2|Bacteria,1G29A@1117|Cyanobacteria,3VMJ4@52604|Pleurocapsales 1117|Cyanobacteria J translation release factor activity - - - - - - - - - - - - - k141_25742_1 1116375.VEJY3_01585 1.51e-104 302.0 COG1438@1|root,COG1438@2|Bacteria,1N2AF@1224|Proteobacteria,1RSF7@1236|Gammaproteobacteria,1XSGI@135623|Vibrionales 135623|Vibrionales K Regulates arginine biosynthesis genes argR GO:0006082,GO:0006355,GO:0006520,GO:0006525,GO:0006807,GO:0008150,GO:0008152,GO:0009064,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031326,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1901564,GO:1901605,GO:1903506,GO:2000112,GO:2001141 - ko:K03402 - - - - ko00000,ko03000 - - - Arg_repressor,Arg_repressor_C k141_25742_2 1116375.VEJY3_01590 4.36e-212 587.0 COG0039@1|root,COG0039@2|Bacteria,1MV57@1224|Proteobacteria,1RMAX@1236|Gammaproteobacteria,1XSFW@135623|Vibrionales 135623|Vibrionales C Catalyzes the reversible oxidation of malate to oxaloacetate mdh GO:0003674,GO:0003824,GO:0004470,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 1.1.1.37 ko:K00024 ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740 R00342,R07136 RC00031 ko00000,ko00001,ko00002,ko01000 - - - Ldh_1_C,Ldh_1_N k141_25742_3 1219076.N646_2515 5.36e-34 117.0 2AWYK@1|root,31NWB@2|Bacteria,1QKJX@1224|Proteobacteria,1TIQ5@1236|Gammaproteobacteria,1XZFZ@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_22042_1 1125863.JAFN01000001_gene1446 4.42e-68 223.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria 28221|Deltaproteobacteria T two component, sigma54 specific, transcriptional regulator, Fis family - - - ko:K02481 - - - - ko00000,ko02022 - - - HTH_8,Response_reg,Sigma54_activat k141_5557_1 218284.CCDN010000001_gene1908 2.34e-81 262.0 COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1TPMS@1239|Firmicutes,4HAQD@91061|Bacilli,1ZATW@1386|Bacillus 91061|Bacilli NT COG0643 Chemotaxis protein histidine kinase and related kinases cheA - 2.7.13.3 ko:K03407 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt,P2 k141_27084_1 1121091.AUMP01000006_gene4105 1.39e-08 54.7 2DTBP@1|root,33JKJ@2|Bacteria,1VKDH@1239|Firmicutes,4I0AV@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - k141_33989_1 1116375.VEJY3_00010 1.38e-96 281.0 COG0369@1|root,COG0369@2|Bacteria,1QUGM@1224|Proteobacteria,1T1YC@1236|Gammaproteobacteria,1XWYJ@135623|Vibrionales 135623|Vibrionales P COG0716 Flavodoxins mioC GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0055114 - ko:K06205 - - - - ko00000 - - - Flavodoxin_1 k141_25771_1 935836.JAEL01000053_gene4892 3.37e-53 175.0 2A8A0@1|root,30XBB@2|Bacteria,1V5X0@1239|Firmicutes,4HHA9@91061|Bacilli,1ZCED@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF3784) - - - - - - - - - - - - DUF3784,bPH_5 k141_35212_1 1267580.AF6_0373 9.95e-64 196.0 2C1CK@1|root,313Y4@2|Bacteria,1V6FR@1239|Firmicutes,4HIGI@91061|Bacilli,21VQD@150247|Anoxybacillus 91061|Bacilli S Zinc-ribbon containing domain ygzB - - - - - - - - - - - DUF2614 k141_36206_1 1120963.KB894502_gene1353 3.64e-69 230.0 COG4104@1|root,COG4104@2|Bacteria,1N0ZK@1224|Proteobacteria,1S9FK@1236|Gammaproteobacteria,2Q363@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria S PAAR motif - - - - - - - - - - - - PAAR_motif k141_36206_3 1116375.VEJY3_19371 6.93e-235 646.0 COG2130@1|root,COG2130@2|Bacteria,1MUC2@1224|Proteobacteria,1RNGM@1236|Gammaproteobacteria,1XT12@135623|Vibrionales 135623|Vibrionales S NADP-dependent oxidoreductases - - - ko:K07119 - - - - ko00000 - - - ADH_N_2,ADH_zinc_N k141_36206_4 1116375.VEJY3_19366 1.31e-85 253.0 COG1846@1|root,COG1846@2|Bacteria,1RH1F@1224|Proteobacteria,1S8WM@1236|Gammaproteobacteria,1Y0WC@135623|Vibrionales 135623|Vibrionales K helix_turn_helix multiple antibiotic resistance protein - - - - - - - - - - - - MarR k141_36206_5 1116375.VEJY3_19361 1.92e-97 285.0 2CFK9@1|root,2Z7KF@2|Bacteria,1PWBU@1224|Proteobacteria,1RPR9@1236|Gammaproteobacteria,1XTGM@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF1439) - - - - - - - - - - - - DUF1439 k141_23380_1 221109.22775916 4.62e-42 143.0 COG1404@1|root,COG1404@2|Bacteria,1VIHE@1239|Firmicutes,4HPPJ@91061|Bacilli 91061|Bacilli O Peptidase inhibitor I9 - - - - - - - - - - - - Inhibitor_I9 k141_32644_1 1502770.JQMG01000001_gene416 0.000279 43.5 COG3219@1|root,COG3219@2|Bacteria,1R8C9@1224|Proteobacteria,2VPVN@28216|Betaproteobacteria,2KMRC@206350|Nitrosomonadales 206350|Nitrosomonadales S Putative DNA-binding domain - - - ko:K09929 - - - - ko00000 - - - DUF2063 k141_32644_2 1279017.AQYJ01000022_gene2741 0.000665 45.4 COG2853@1|root,COG2853@2|Bacteria,1MVX0@1224|Proteobacteria,1RNPS@1236|Gammaproteobacteria,466E2@72275|Alteromonadaceae 1236|Gammaproteobacteria M Surface lipoprotein vacJ - - ko:K04754 - - - - ko00000 - - - MlaA k141_35213_2 218284.CCDN010000006_gene3632 1.93e-21 90.1 COG2755@1|root,COG2755@2|Bacteria,1UZKM@1239|Firmicutes,4HVJ0@91061|Bacilli,1ZEST@1386|Bacillus 91061|Bacilli E GDSL-like Lipase/Acylhydrolase - - - - - - - - - - - - Lipase_GDSL_2 k141_20792_1 218284.CCDN010000001_gene72 1.45e-80 244.0 COG0325@1|root,COG0325@2|Bacteria,1TRDN@1239|Firmicutes,4HC45@91061|Bacilli,1ZARM@1386|Bacillus 91061|Bacilli S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis ylmE GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 - ko:K06997 - - - - ko00000 - - - Ala_racemase_N k141_24451_1 1279017.AQYJ01000025_gene566 1.65e-97 293.0 28JIP@1|root,2Z82C@2|Bacteria,1R5N9@1224|Proteobacteria,1RY8I@1236|Gammaproteobacteria,465MK@72275|Alteromonadaceae 1236|Gammaproteobacteria S S1 P1 nuclease - - 3.1.30.1 ko:K05986 - - - - ko00000,ko01000 - - - S1-P1_nuclease k141_24451_4 1042377.AFPJ01000028_gene2229 2.78e-154 446.0 COG4324@1|root,COG4324@2|Bacteria,1N0FE@1224|Proteobacteria,1S0UK@1236|Gammaproteobacteria,46ACH@72275|Alteromonadaceae 1236|Gammaproteobacteria S Putative aminopeptidase - - - - - - - - - - - - Aminopep k141_24451_5 1042377.AFPJ01000028_gene2228 2.33e-71 218.0 COG1490@1|root,COG1490@2|Bacteria,1RGTV@1224|Proteobacteria,1S61I@1236|Gammaproteobacteria,467IU@72275|Alteromonadaceae 1236|Gammaproteobacteria J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality dtd GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106026,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - ko:K07560 - - - - ko00000,ko01000,ko03016 - - - Tyr_Deacylase k141_24451_6 1042377.AFPJ01000028_gene2227 0.0 1181.0 COG1505@1|root,COG1505@2|Bacteria,1NZ7N@1224|Proteobacteria,1T1KJ@1236|Gammaproteobacteria,46621@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG1505 Serine proteases of the peptidase family S9A - - 3.4.21.26 ko:K01322 ko04614,map04614 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S9,Peptidase_S9_N k141_24451_7 1453501.JELR01000002_gene1270 1.31e-208 609.0 COG4935@1|root,COG4935@2|Bacteria 2|Bacteria O Belongs to the peptidase S8 family - - - - - - - - - - - - NPCBM_assoc,P_proprotein,Peptidase_M36 k141_13944_1 1294265.JCM21738_1780 1.45e-133 379.0 COG0746@1|root,COG0746@2|Bacteria,1VA6T@1239|Firmicutes,4HPX3@91061|Bacilli,1ZIA7@1386|Bacillus 91061|Bacilli H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor mobA - 2.7.7.77 ko:K03752 ko00790,ko01100,map00790,map01100 - R11581 - ko00000,ko00001,ko01000 - - - NTP_transf_3 k141_25772_1 218284.CCDN010000006_gene3533 9.84e-82 257.0 COG1075@1|root,COG1075@2|Bacteria,1TQFF@1239|Firmicutes,4HDQN@91061|Bacilli,1ZCCU@1386|Bacillus 91061|Bacilli S acetyltransferases and hydrolases with the alpha beta hydrolase fold lipA1 - - - - - - - - - - - DUF676,PGAP1 k141_12755_1 218284.CCDN010000001_gene142 3.56e-83 262.0 COG1217@1|root,COG1217@2|Bacteria,1TQ5Y@1239|Firmicutes,4HAQ6@91061|Bacilli,1ZB9R@1386|Bacillus 91061|Bacilli T GTP-binding protein TypA typA - - ko:K06207 - - - - ko00000 - - - EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2 k141_6807_10 697281.Mahau_2905 1.85e-41 141.0 2EAJK@1|root,334NE@2|Bacteria,1VGIB@1239|Firmicutes,252R9@186801|Clostridia 186801|Clostridia S PFAM Phage major tail protein 2 - - - - - - - - - - - - Phage_tail_2 k141_6807_12 10724.O48447_BPSPP 3.97e-18 82.4 4QB1F@10239|Viruses,4QPSW@28883|Caudovirales,4QKPW@10699|Siphoviridae 10699|Siphoviridae S exonuclease activity - - - - - - - - - - - - - k141_6807_17 173707.Q79S85_9CAUD 1.3e-85 263.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - GO:0005575,GO:0019012,GO:0019028,GO:0032991,GO:0044423,GO:0046806 - - - - - - - - - - - k141_6807_18 935836.JAEL01000086_gene55 1.88e-57 186.0 2DPCU@1|root,331IS@2|Bacteria,1VFIK@1239|Firmicutes,4HPAM@91061|Bacilli,1ZMPF@1386|Bacillus 91061|Bacilli S Phage minor structural protein GP20 - - - - - - - - - - - - Phage_GP20 k141_6807_19 279010.BL00982 2.64e-92 283.0 COG2369@1|root,COG2369@2|Bacteria,1V2JT@1239|Firmicutes,4HFSR@91061|Bacilli,1ZIIA@1386|Bacillus 91061|Bacilli S Phage Mu protein F like protein - - - - - - - - - - - - Phage_Mu_F k141_6807_20 1118054.CAGW01000107_gene3672 1.61e-10 63.2 2CEGT@1|root,2Z7ZB@2|Bacteria,1TP3Y@1239|Firmicutes,4HDQK@91061|Bacilli,26VYN@186822|Paenibacillaceae 91061|Bacilli S Phage portal protein, SPP1 Gp6-like - - - - - - - - - - - - Phage_prot_Gp6 k141_23568_1 218284.CCDN010000002_gene2867 2.44e-96 299.0 COG1858@1|root,COG3391@1|root,COG1858@2|Bacteria,COG3391@2|Bacteria,1V255@1239|Firmicutes,4HEF2@91061|Bacilli,1ZPVH@1386|Bacillus 91061|Bacilli P Lactonase, 7-bladed beta-propeller - - - - - - - - - - - - Cytochrom_D1,DHOR,Lactonase k141_34095_1 406124.ACPC01000019_gene3275 3.73e-39 146.0 COG1396@1|root,COG1396@2|Bacteria,1V1KD@1239|Firmicutes,4HG1Q@91061|Bacilli,1ZEYC@1386|Bacillus 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_19,HTH_3,TPR_12,TPR_8 k141_22240_2 218284.CCDN010000001_gene1641 1.41e-99 294.0 COG1388@1|root,COG1388@2|Bacteria,1V5F7@1239|Firmicutes,4HH73@91061|Bacilli,1ZGCI@1386|Bacillus 91061|Bacilli M LysM domain - - - - - - - - - - - - - k141_891_1 1453501.JELR01000002_gene766 8.56e-130 374.0 COG0861@1|root,COG0861@2|Bacteria,1MWC9@1224|Proteobacteria,1T1GE@1236|Gammaproteobacteria,4670C@72275|Alteromonadaceae 1236|Gammaproteobacteria P Integral membrane protein TerC family ygdQ GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - TerC k141_891_2 1168067.JAGP01000001_gene2070 1.68e-55 176.0 2DMKI@1|root,32S70@2|Bacteria,1N1FV@1224|Proteobacteria,1S778@1236|Gammaproteobacteria 1236|Gammaproteobacteria S SpoIIAA-like VVA0543 - - - - - - - - - - - SpoIIAA-like k141_22241_1 1267533.KB906736_gene961 4.85e-48 157.0 COG1725@1|root,COG1725@2|Bacteria,3Y5VN@57723|Acidobacteria,2JK5T@204432|Acidobacteriia 2|Bacteria K helix_turn_helix gluconate operon transcriptional repressor ytrA - - ko:K07979 - - - - ko00000,ko03000 - - - GntR k141_36287_1 94122.Shewana3_4100 8.74e-21 95.1 COG0859@1|root,COG0859@2|Bacteria,1MYZA@1224|Proteobacteria,1RR6K@1236|Gammaproteobacteria,2Q8GQ@267890|Shewanellaceae 1236|Gammaproteobacteria M PFAM glycosyl transferase family 9 opsX GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - ko:K12982 - - - - ko00000,ko01000,ko01003,ko01005 - GT9 - Glyco_transf_9 k141_14152_1 1415778.JQMM01000001_gene2040 3.36e-20 87.8 COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,1RMS5@1236|Gammaproteobacteria,1J53X@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate pdxJ GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 ko:K03474 ko00750,ko01100,map00750,map01100 M00124 R05838 RC01476 ko00000,ko00001,ko00002,ko01000 - - - PdxJ k141_14152_2 1265505.ATUG01000001_gene4474 1.03e-28 119.0 COG5495@1|root,COG5495@2|Bacteria,1RBEZ@1224|Proteobacteria,42PJR@68525|delta/epsilon subdivisions,2WPBQ@28221|Deltaproteobacteria,2MI0V@213118|Desulfobacterales 28221|Deltaproteobacteria S Domain of unknown function (DUF2520) - - - - - - - - - - - - DUF2520,Rossmann-like k141_14152_3 1279017.AQYJ01000026_gene372 1.08e-144 412.0 COG0566@1|root,COG0566@2|Bacteria,1MWCM@1224|Proteobacteria,1RY7P@1236|Gammaproteobacteria,4667M@72275|Alteromonadaceae 1236|Gammaproteobacteria J RNA 2'-O ribose methyltransferase substrate binding - - 2.1.1.185 ko:K03218 - - - - ko00000,ko01000,ko03009 - - - SpoU_methylase,SpoU_sub_bind k141_14152_4 1123279.ATUS01000001_gene2416 4.37e-29 125.0 COG2885@1|root,COG2885@2|Bacteria,1R4WG@1224|Proteobacteria,1RZN8@1236|Gammaproteobacteria,1J93K@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Opacity family porin protein - - - ko:K03286 - - - - ko00000,ko02000 1.B.6 - - OMP_b-brl,OmpA,TSP_3 k141_25903_1 218284.CCDN010000001_gene1524 3.59e-118 358.0 COG0550@1|root,COG0550@2|Bacteria,1TPJD@1239|Firmicutes,4HAZV@91061|Bacilli,1ZBEG@1386|Bacillus 91061|Bacilli L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topB - 5.99.1.2 ko:K03169 - - - - ko00000,ko01000,ko03032 - - - Topoisom_bac,Toprim,Toprim_Crpt k141_17359_1 1279017.AQYJ01000024_gene838 9.75e-242 672.0 COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,1RMR2@1236|Gammaproteobacteria,464J6@72275|Alteromonadaceae 1236|Gammaproteobacteria G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate glmM - 5.4.2.10 ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 - R02060 RC00408 ko00000,ko00001,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV k141_27255_1 1128912.GMES_1984 3.75e-51 192.0 28HBN@1|root,2Z7NM@2|Bacteria,1NXQY@1224|Proteobacteria,1SBXN@1236|Gammaproteobacteria,46C85@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_10409_1 932213.SPM24T3_09831 3.94e-48 159.0 COG0778@1|root,COG0778@2|Bacteria,1R9VX@1224|Proteobacteria,1RNQE@1236|Gammaproteobacteria 1236|Gammaproteobacteria C May reduce toxic product malonic semialdehyde to 3- hydroxypropionic acid, which is excreted rutE GO:0000166,GO:0003674,GO:0005488,GO:0006139,GO:0006206,GO:0006208,GO:0006212,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0010181,GO:0017144,GO:0019740,GO:0019860,GO:0032553,GO:0033554,GO:0034641,GO:0036094,GO:0042737,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0046113,GO:0046483,GO:0046700,GO:0048037,GO:0050662,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - ko:K09019 ko00240,ko01100,map00240,map01100 - R09289 RC00087 ko00000,ko00001,ko01000 - - iEC042_1314.EC042_1083,iECO103_1326.ECO103_1054,iG2583_1286.G2583_1241 Nitroreductase k141_10409_2 1279017.AQYJ01000026_gene50 7.41e-50 164.0 2DR7N@1|root,33AJV@2|Bacteria,1NGUY@1224|Proteobacteria,1SGQC@1236|Gammaproteobacteria,468F9@72275|Alteromonadaceae 1236|Gammaproteobacteria M Protein of unknown function (DUF3429) VPA1252 - - - - - - - - - - - DUF3429 k141_14994_2 1453501.JELR01000002_gene460 6.5e-185 522.0 COG3182@1|root,COG3182@2|Bacteria,1MW2S@1224|Proteobacteria,1RQYY@1236|Gammaproteobacteria,46636@72275|Alteromonadaceae 1236|Gammaproteobacteria S PepSY-associated TM region - - - - - - - - - - - - PepSY_TM k141_23570_1 551275.KB899544_gene1138 2.48e-48 162.0 COG1416@1|root,COG1416@2|Bacteria,1RI2V@1224|Proteobacteria,2U98Z@28211|Alphaproteobacteria,43Y71@69657|Hyphomonadaceae 28211|Alphaproteobacteria S DsrE/DsrF-like family - - - - - - - - - - - - DrsE k141_9249_1 1279017.AQYJ01000022_gene2646 3.56e-97 291.0 COG1683@1|root,COG3272@1|root,COG1683@2|Bacteria,COG3272@2|Bacteria,1MXYZ@1224|Proteobacteria,1RNMF@1236|Gammaproteobacteria,464ZQ@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF1722) ybgA - - - - - - - - - - - DUF1722,DUF523 k141_9249_2 644801.Psest_2396 1.52e-37 143.0 COG0789@1|root,COG0789@2|Bacteria,1R9SN@1224|Proteobacteria,1S78T@1236|Gammaproteobacteria,1Z1RJ@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria K transcriptional - - - ko:K22491 - - - - ko00000,ko03000 - - - MerR_1 k141_9249_3 1279017.AQYJ01000022_gene2648 4.24e-65 214.0 COG0415@1|root,COG0415@2|Bacteria,1MV9Y@1224|Proteobacteria,1RNGJ@1236|Gammaproteobacteria,4651X@72275|Alteromonadaceae 1236|Gammaproteobacteria L Belongs to the DNA photolyase family phrB GO:0003674,GO:0003824,GO:0003904,GO:0003913,GO:0006139,GO:0006259,GO:0006281,GO:0006464,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0018298,GO:0019538,GO:0033554,GO:0034641,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360,GO:1901564 4.1.99.3 ko:K01669 - - - - ko00000,ko01000,ko03400 - - - DNA_photolyase,FAD_binding_7 k141_7880_1 218284.CCDN010000001_gene1898 2.88e-165 464.0 COG0020@1|root,COG0020@2|Bacteria,1TQTS@1239|Firmicutes,4HA37@91061|Bacilli,1ZC2T@1386|Bacillus 91061|Bacilli I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids uppS GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 ko:K00806 ko00900,ko01110,map00900,map01110 - R06447 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 - - - Prenyltransf k141_19876_1 1347086.CCBA010000010_gene1735 9.39e-38 135.0 COG2267@1|root,COG2267@2|Bacteria,1V0IY@1239|Firmicutes,4HBP3@91061|Bacilli,1ZFXU@1386|Bacillus 91061|Bacilli I Alpha beta hydrolase - - - - - - - - - - - - Abhydrolase_1,Hydrolase_4 k141_11629_1 223926.28805166 2.29e-150 424.0 COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,1RP86@1236|Gammaproteobacteria,1XTU6@135623|Vibrionales 135623|Vibrionales E Belongs to the UPF0758 family radC GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - ko:K03630 - - - - ko00000 - - - RadC k141_11629_2 223926.28805165 0.0 917.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMV2@1236|Gammaproteobacteria,1XSAN@135623|Vibrionales 135623|Vibrionales T methyl-accepting chemotaxis protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal,sCache_2 k141_11629_3 223926.28805163 1.76e-260 717.0 COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,1RMKQ@1236|Gammaproteobacteria,1XT15@135623|Vibrionales 135623|Vibrionales H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine coaBC - 4.1.1.36,6.3.2.5 ko:K13038 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 - - - DFP,Flavoprotein k141_4319_1 1121091.AUMP01000003_gene2914 1.19e-84 258.0 COG1011@1|root,COG1011@2|Bacteria,1TS3W@1239|Firmicutes,4HADE@91061|Bacilli 91061|Bacilli S hydrolase (HAD superfamily) ysaA - 3.1.3.5,3.8.1.2 ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346,R05287 RC00017,RC00697 ko00000,ko00001,ko01000 - - - HAD_2 k141_16226_1 1440774.Y900_010565 5.35e-31 121.0 COG2220@1|root,COG2220@2|Bacteria,2GMFQ@201174|Actinobacteria,234N4@1762|Mycobacteriaceae 201174|Actinobacteria S Zn-dependent hydrolases of the beta-lactamase fold - - - - - - - - - - - - Lactamase_B,Lactamase_B_2 k141_893_1 42565.FP66_15650 2.22e-140 419.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria 1224|Proteobacteria T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF k141_37507_1 218284.CCDN010000008_gene4263 1.87e-83 264.0 COG4477@1|root,COG4477@2|Bacteria,1TQR7@1239|Firmicutes,4HA15@91061|Bacilli,1ZAWX@1386|Bacillus 91061|Bacilli D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization ezrA GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000918,GO:0000921,GO:0005575,GO:0005623,GO:0005886,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0022402,GO:0022607,GO:0031106,GO:0032185,GO:0032506,GO:0034622,GO:0043933,GO:0044085,GO:0044464,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051301,GO:0051302,GO:0051781,GO:0061640,GO:0065003,GO:0065007,GO:0070925,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 - ko:K06286 - - - - ko00000,ko03036 - - - EzrA k141_34097_1 218284.CCDN010000004_gene3109 5.63e-29 110.0 COG4989@1|root,COG4989@2|Bacteria,1TQ12@1239|Firmicutes,4HA57@91061|Bacilli,1ZD8D@1386|Bacillus 91061|Bacilli S Oxidoreductase ycsN - - - - - - - - - - - Aldo_ket_red k141_19877_1 1116375.VEJY3_18551 6.11e-64 205.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RM93@1236|Gammaproteobacteria,1Y072@135623|Vibrionales 135623|Vibrionales I Thiolase, C-terminal domain - - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N k141_27257_1 1462526.BN990_00995 8.87e-88 266.0 COG1309@1|root,COG1309@2|Bacteria,1UDHR@1239|Firmicutes,4HFAX@91061|Bacilli 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - TetR_N k141_11630_1 1453501.JELR01000002_gene1331 5.6e-50 162.0 2B4XH@1|root,31XQC@2|Bacteria,1RHJF@1224|Proteobacteria,1S3S1@1236|Gammaproteobacteria,467JQ@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_11630_2 1042377.AFPJ01000028_gene2162 2.5e-19 88.2 COG0457@1|root,COG0457@2|Bacteria,1MXSS@1224|Proteobacteria,1S157@1236|Gammaproteobacteria,467PR@72275|Alteromonadaceae 1236|Gammaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16,TPR_6 k141_17360_1 292564.Cyagr_0351 3.3e-10 65.5 COG3187@1|root,COG3187@2|Bacteria,1GMTF@1117|Cyanobacteria,22TW4@167375|Cyanobium 1117|Cyanobacteria O META domain - - - - - - - - - - - - META k141_6808_1 223926.28807696 0.0 929.0 COG3164@1|root,COG3164@2|Bacteria,1MXWF@1224|Proteobacteria,1RNUK@1236|Gammaproteobacteria,1XTHT@135623|Vibrionales 135623|Vibrionales S Protein of unknown function VV2929 - - - - - - - - - - - AsmA_2,DUF3971 k141_14995_1 42565.FP66_06465 1.15e-121 382.0 COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,1RPYH@1236|Gammaproteobacteria,1XH56@135619|Oceanospirillales 135619|Oceanospirillales K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoC - 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 k141_22243_2 1279017.AQYJ01000028_gene2166 3.47e-51 172.0 COG1253@1|root,COG1253@2|Bacteria,1MWT3@1224|Proteobacteria,1RQBC@1236|Gammaproteobacteria,465JI@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG1253 Hemolysins and related proteins containing CBS domains - - - - - - - - - - - - CBS,DUF21 k141_3101_1 491915.Aflv_1986 1.11e-06 50.1 COG0842@1|root,COG0842@2|Bacteria,1TQG7@1239|Firmicutes,4H9MK@91061|Bacilli,21VF3@150247|Anoxybacillus 91061|Bacilli V ABC-2 type transporter - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane,ABC2_membrane_3 k141_3101_2 218284.CCDN010000007_gene3922 4.06e-136 387.0 COG1309@1|root,COG1309@2|Bacteria,1V3R8@1239|Firmicutes,4HBEK@91061|Bacilli,1ZDP2@1386|Bacillus 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - TetR_N k141_24626_1 1294265.JCM21738_1986 7.62e-90 263.0 29RAQ@1|root,30CCF@2|Bacteria,1U9MH@1239|Firmicutes,4IJSY@91061|Bacilli,1ZG4U@1386|Bacillus 91061|Bacilli S Family of unknown function (DUF5365) yhcU - - - - - - - - - - - DUF5365 k141_6836_1 649639.Bcell_2950 1.27e-11 65.1 COG1296@1|root,COG1296@2|Bacteria,1TSXD@1239|Firmicutes,4HJCQ@91061|Bacilli,1ZDNM@1386|Bacillus 91061|Bacilli E branched-chain amino acid - - - - - - - - - - - - AzlC k141_6836_2 36630.CADNFIAP00004392 5.86e-18 84.3 COG1396@1|root,2RJHX@2759|Eukaryota,38P7M@33154|Opisthokonta,3PR2V@4751|Fungi,3RAJR@4890|Ascomycota,20Q3B@147545|Eurotiomycetes,3SAHP@5042|Eurotiales 4751|Fungi K Methyltransferase domain - - - - - - - - - - - - Methyltransf_25 k141_34111_1 218284.CCDN010000001_gene1600 1.44e-20 86.7 2A2R1@1|root,30R3Y@2|Bacteria,1U9MP@1239|Firmicutes,4IJT4@91061|Bacilli,1ZE7Q@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_4331_2 264732.Moth_2104 1.6e-07 58.5 COG0791@1|root,COG1388@1|root,COG0791@2|Bacteria,COG1388@2|Bacteria,1V9ZW@1239|Firmicutes,25AZU@186801|Clostridia 186801|Clostridia M NlpC p60 family spr - - ko:K19224,ko:K21471 - - - - ko00000,ko01000,ko01002,ko01011 - CBM50 - LysM,NLPC_P60,SH3_3 k141_3117_1 1194165.CAJF01000001_gene1896 2.52e-24 98.2 COG0315@1|root,COG0315@2|Bacteria,2IHR6@201174|Actinobacteria,4FNWJ@85023|Microbacteriaceae 201174|Actinobacteria H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) moaC - 4.6.1.17 ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R11372 RC03425 ko00000,ko00001,ko01000 - - - MoaC k141_912_2 666686.B1NLA3E_08870 4.12e-13 65.1 29S5B@1|root,30D9U@2|Bacteria,1UB1P@1239|Firmicutes,4IMEJ@91061|Bacilli,1ZJZ0@1386|Bacillus 91061|Bacilli S Fur-regulated basic protein A - - - - - - - - - - - - Fur_reg_FbpA k141_912_3 398511.BpOF4_05220 5.01e-55 173.0 COG1145@1|root,32SB1@2|Bacteria,1V6N0@1239|Firmicutes,4HIWV@91061|Bacilli,1ZIM7@1386|Bacillus 91061|Bacilli C COG1145 Ferredoxin - - - - - - - - - - - - DUF326 k141_32805_1 218284.CCDN010000001_gene1863 9.51e-143 411.0 COG0612@1|root,COG0612@2|Bacteria,1TP5I@1239|Firmicutes,4H9YG@91061|Bacilli,1ZBXQ@1386|Bacillus 91061|Bacilli S zinc protease ymfH - - - - - - - - - - - Peptidase_M16,Peptidase_M16_C k141_32805_2 218284.CCDN010000001_gene1864 3.24e-63 205.0 COG0612@1|root,COG0612@2|Bacteria,1TPN6@1239|Firmicutes,4H9P5@91061|Bacilli,1ZCAJ@1386|Bacillus 91061|Bacilli S Peptidase M16 albE - - - - - - - - - - - Peptidase_M16_C k141_24627_1 1078085.HMPREF1210_01923 5.07e-79 246.0 COG2204@1|root,COG4963@1|root,COG2204@2|Bacteria,COG4963@2|Bacteria,1UF2S@1239|Firmicutes,4HDR8@91061|Bacilli,26GA6@186818|Planococcaceae 91061|Bacilli D AAA domain - - - ko:K02282 - - - - ko00000,ko02035,ko02044 - - - AAA_31,Response_reg k141_27273_1 1385514.N782_12480 1.93e-107 340.0 COG0454@1|root,COG0456@2|Bacteria,1TQQA@1239|Firmicutes,4HBXN@91061|Bacilli,2YBGI@289201|Pontibacillus 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10 k141_6837_1 313603.FB2170_14983 1.99e-06 53.1 COG2010@1|root,COG2010@2|Bacteria,4NIRV@976|Bacteroidetes,1HX5S@117743|Flavobacteriia 976|Bacteroidetes C Cytochrome c - - - - - - - - - - - - Cytochrom_C,DUF3365 k141_11651_1 1279017.AQYJ01000020_gene1267 6.05e-81 263.0 COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,1RMGA@1236|Gammaproteobacteria,46478@72275|Alteromonadaceae 1236|Gammaproteobacteria L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG GO:0003674,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB_bind,DnaG_DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2 k141_18857_1 1121091.AUMP01000052_gene1290 3.55e-51 173.0 COG2367@1|root,COG2367@2|Bacteria,1UYZ3@1239|Firmicutes,4HD7T@91061|Bacilli 91061|Bacilli V Beta-lactamase enzyme family - - 3.5.2.6 ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 M00627,M00628 R06363 RC01499 ko00000,ko00001,ko00002,ko01000,ko01504 - - - Beta-lactamase2 k141_10411_1 1042377.AFPJ01000005_gene2463 1.41e-25 100.0 COG4665@1|root,COG4665@2|Bacteria,1RHBW@1224|Proteobacteria,1S5Y0@1236|Gammaproteobacteria,467SF@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Tripartite ATP-independent periplasmic transporters, DctQ component gtrA - - - - - - - - - - - DctQ k141_10411_2 1042377.AFPJ01000005_gene2464 5.4e-219 608.0 COG0226@1|root,COG0226@2|Bacteria,1MUH9@1224|Proteobacteria,1RN9U@1236|Gammaproteobacteria,464BK@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0226 ABC-type phosphate transport system, periplasmic component pstS - - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - PBP_like_2 k141_12872_1 218284.CCDN010000007_gene3910 2.51e-100 303.0 COG2031@1|root,COG2031@2|Bacteria,1TPCQ@1239|Firmicutes,4HAQF@91061|Bacilli,1ZECR@1386|Bacillus 91061|Bacilli I Short chain fatty acid transporter atoE - - ko:K02106 ko02020,map02020 - - - ko00000,ko00001 2.A.73.1 - - SCFA_trans k141_16245_1 587753.EY04_14815 2.49e-07 53.1 COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,1S607@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Belongs to the small heat shock protein (HSP20) family - - - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 k141_31494_1 1279017.AQYJ01000026_gene371 1.98e-60 197.0 COG5495@1|root,COG5495@2|Bacteria,1RBEZ@1224|Proteobacteria,1S847@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF2520) - - - - - - - - - - - - DUF2520,F420_oxidored,Rossmann-like k141_36302_2 218284.CCDN010000006_gene3520 8.64e-48 153.0 2E37R@1|root,32Y7E@2|Bacteria,1VEJ6@1239|Firmicutes,4HNWR@91061|Bacilli,1ZIXG@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_36302_3 218284.CCDN010000006_gene3521 1.31e-70 213.0 COG5577@1|root,COG5577@2|Bacteria,1V96G@1239|Firmicutes,4HK73@91061|Bacilli,1ZHVT@1386|Bacillus 91061|Bacilli M Coat F domain yusN - - - - - - - - - - - Coat_F k141_24628_1 1042377.AFPJ01000032_gene2722 6.61e-97 288.0 COG1073@1|root,COG1073@2|Bacteria 2|Bacteria S thiolester hydrolase activity MA20_16590 - - ko:K06889,ko:K07397 - - - - ko00000 - - - Hydrolase_4,OsmC k141_24628_2 1453501.JELR01000002_gene1500 5.61e-35 119.0 2EGSV@1|root,33AIZ@2|Bacteria,1NGPG@1224|Proteobacteria,1SGM3@1236|Gammaproteobacteria 1236|Gammaproteobacteria S LITAF-like zinc ribbon domain containing protein - - - - - - - - - - - - Cys_rich_CPXG k141_15015_1 686578.AFFX01000010_gene2462 2.3e-105 327.0 COG0243@1|root,COG0243@2|Bacteria,1MU6B@1224|Proteobacteria,1RNXW@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family ydeP - 1.17.1.9 ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001,ko01000 - - - Molybdopterin,Molydop_binding k141_30320_1 574375.BAGA_18825 2.28e-75 255.0 COG4926@1|root,COG4926@2|Bacteria,1TQHW@1239|Firmicutes,4HFA8@91061|Bacilli,1ZPV9@1386|Bacillus 91061|Bacilli S Prophage endopeptidase tail - - - - - - - - - - - - Prophage_tail k141_32806_1 218284.CCDN010000002_gene2078 7.41e-189 535.0 COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4HC58@91061|Bacilli,1ZB1Y@1386|Bacillus 91061|Bacilli S COG0488 ATPase components of ABC transporters with duplicated ATPase domains yheS_1 - - - - - - - - - - - ABC_tran,ABC_tran_Xtn k141_3118_1 1294265.JCM21738_3511 1.77e-118 345.0 COG1001@1|root,COG1001@2|Bacteria,1TP84@1239|Firmicutes,4HAIR@91061|Bacilli,1ZAY2@1386|Bacillus 91061|Bacilli F adenine deaminase yerA GO:0003674,GO:0003824,GO:0006040,GO:0006044,GO:0006046,GO:0008150,GO:0008152,GO:0008448,GO:0009056,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0046348,GO:0071704,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901575 3.5.4.2 ko:K01486 ko00230,ko01100,map00230,map01100 - R01244 RC00477 ko00000,ko00001,ko01000 - - - Adenine_deam_C,Amidohydro_1 k141_3118_2 1294265.JCM21738_3510 1.86e-33 116.0 2EAXM@1|root,334YP@2|Bacteria,1VIHS@1239|Firmicutes,4HR0C@91061|Bacilli,1ZJ0E@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2892) - - - - - - - - - - - - DUF2892 k141_1877_1 2055.JNXA01000003_gene4567 4.28e-18 89.0 COG2021@1|root,COG2021@2|Bacteria,2GMXN@201174|Actinobacteria,4GAX9@85026|Gordoniaceae 201174|Actinobacteria E Serine aminopeptidase, S33 - - - ko:K16434 ko01055,map01055 - - - ko00000,ko00001 - - - Abhydrolase_1,Abhydrolase_6 k141_1877_2 1042377.AFPJ01000016_gene126 4.68e-146 423.0 COG3239@1|root,COG3239@2|Bacteria,1MW29@1224|Proteobacteria,1RPHS@1236|Gammaproteobacteria,46AIU@72275|Alteromonadaceae 1236|Gammaproteobacteria I Fatty acid desaturase alkB2 GO:0003674,GO:0003824,GO:0004497,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016491,GO:0016705,GO:0016713,GO:0018685,GO:0043446,GO:0043448,GO:0044237,GO:0044248,GO:0055114,GO:0071704,GO:1901575 1.14.15.3 ko:K00496 ko00071,ko00930,map00071,map00930 - R01347,R02281,R06945 RC00478 ko00000,ko00001,ko01000 - - - FA_desaturase,Rubredoxin k141_1877_3 1182590.BN5_00761 4.65e-36 131.0 COG2353@1|root,COG2353@2|Bacteria,1MZDI@1224|Proteobacteria,1S9EZ@1236|Gammaproteobacteria,1YGA8@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S Belongs to the UPF0312 family - - - - - - - - - - - - YceI k141_1877_5 589873.EP13_16805 1.17e-122 363.0 COG2234@1|root,COG2234@2|Bacteria,1MWBX@1224|Proteobacteria,1RYHQ@1236|Gammaproteobacteria,465S8@72275|Alteromonadaceae 1236|Gammaproteobacteria S Fibronectin type 3 domain - - - - - - - - - - - - Peptidase_M28,fn3 k141_19887_1 1283284.AZUK01000001_gene2269 2.67e-94 289.0 COG4989@1|root,COG4989@2|Bacteria,1MY3G@1224|Proteobacteria,1RRIC@1236|Gammaproteobacteria,1Y4PW@135624|Aeromonadales 135624|Aeromonadales S Aldo/keto reductase family - - - - - - - - - - - - Aldo_ket_red k141_19887_3 1453501.JELR01000005_gene1700 3.3e-186 536.0 COG0596@1|root,COG0596@2|Bacteria,1R6KU@1224|Proteobacteria,1RNTQ@1236|Gammaproteobacteria,467P9@72275|Alteromonadaceae 1236|Gammaproteobacteria S TAP-like protein - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_4 k141_36439_2 1116375.VEJY3_04080 2.98e-189 528.0 COG1535@1|root,COG3433@1|root,COG1535@2|Bacteria,COG3433@2|Bacteria,1MW2U@1224|Proteobacteria,1RRZ8@1236|Gammaproteobacteria,1XW2I@135623|Vibrionales 135623|Vibrionales Q Involved in the biosynthesis of the catechol siderophore vibriobactin. Vibriobactin is a chelating compound involved in transporting iron from the bacterial environment into the cell cytoplasm vibB - 3.3.2.1,6.3.2.14 ko:K01252 ko01053,ko01110,ko01130,map01053,map01110,map01130 - R03037,R07644 RC00162,RC00350,RC02148,RC03046 ko00000,ko00001,ko01000,ko01008 - - - Isochorismatase,PP-binding k141_36439_3 1116375.VEJY3_04075 0.0 945.0 COG1021@1|root,COG1021@2|Bacteria,1NSN8@1224|Proteobacteria,1RP8K@1236|Gammaproteobacteria,1XTWS@135623|Vibrionales 135623|Vibrionales Q 2,3-dihydroxybenzoate-AMP ligase entE GO:0003674,GO:0003824,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008668,GO:0009058,GO:0009237,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0019184,GO:0019290,GO:0019748,GO:0034641,GO:0043043,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044550,GO:0051186,GO:0051188,GO:0070566,GO:0071704,GO:1901564,GO:1901566,GO:1901576 2.7.7.58,6.3.2.14 ko:K02363 ko01053,ko01110,ko01130,map01053,map01110,map01130 - R07644 RC00162,RC03046 ko00000,ko00001,ko01000,ko01008 - - - AMP-binding,AMP-binding_C k141_36439_4 1116375.VEJY3_04070 8.18e-252 694.0 COG1169@1|root,COG1169@2|Bacteria,1MVB7@1224|Proteobacteria,1RRBX@1236|Gammaproteobacteria,1XVJS@135623|Vibrionales 135623|Vibrionales HQ Isochorismate synthase vibC GO:0003674,GO:0003824,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008909,GO:0009058,GO:0009237,GO:0009987,GO:0016853,GO:0016866,GO:0019184,GO:0019290,GO:0019748,GO:0034641,GO:0043043,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044550,GO:0050486,GO:0051186,GO:0051188,GO:0071704,GO:1901564,GO:1901566,GO:1901576 5.4.4.2 ko:K02361 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 M00116 R01717 RC00588 ko00000,ko00001,ko00002,ko01000 - - - Chorismate_bind k141_17550_1 218284.CCDN010000001_gene96 2.08e-72 228.0 COG1893@1|root,COG1893@2|Bacteria,1V1NJ@1239|Firmicutes,4HFWT@91061|Bacilli,1ZFJY@1386|Bacillus 91061|Bacilli H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid panE GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008677,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU15110 ApbA,ApbA_C k141_21090_1 1279017.AQYJ01000023_gene3200 4.78e-44 147.0 COG1226@1|root,31669@2|Bacteria,1RIW0@1224|Proteobacteria,1S6HC@1236|Gammaproteobacteria,4688E@72275|Alteromonadaceae 1236|Gammaproteobacteria P Ion transport 2 domain protein - - - - - - - - - - - - Ion_trans_2 k141_21090_2 1177179.A11A3_02262 9.73e-21 86.3 COG0590@1|root,COG0590@2|Bacteria,1RGU0@1224|Proteobacteria,1S60Z@1236|Gammaproteobacteria,1XK7D@135619|Oceanospirillales 135619|Oceanospirillales FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) tadA - 3.5.4.33 ko:K11991 - - R10223 RC00477 ko00000,ko01000,ko03016 - - - MafB19-deam,dCMP_cyt_deam_1 k141_24838_2 218284.CCDN010000002_gene2277 5.38e-52 167.0 2D0AC@1|root,32T87@2|Bacteria,1V6E3@1239|Firmicutes,4HIHJ@91061|Bacilli,1ZHXF@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_2072_2 67281.JNZZ01000023_gene4019 9.61e-07 52.4 COG1595@1|root,COG1595@2|Bacteria,2GN5Y@201174|Actinobacteria,418DJ@629295|Streptomyces griseus group 201174|Actinobacteria K Sigma-70 region 2 - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4,Sigma70_r4_2 k141_29543_1 42565.FP66_12150 1.77e-29 109.0 COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,1RMSY@1236|Gammaproteobacteria,1XJT5@135619|Oceanospirillales 135619|Oceanospirillales H Riboflavin synthase ribE - 2.5.1.9 ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00066 RC00958,RC00960 ko00000,ko00001,ko00002,ko01000 - - - Lum_binding k141_15162_1 452637.Oter_4168 2.97e-40 142.0 COG0396@1|root,COG0396@2|Bacteria,46SGE@74201|Verrucomicrobia,3K7KH@414999|Opitutae 414999|Opitutae O ABC transporter - - - ko:K09013 - - - - ko00000,ko02000 - - - ABC_tran k141_17551_1 218284.CCDN010000001_gene1512 2.17e-114 335.0 COG0709@1|root,COG0709@2|Bacteria,1TQCJ@1239|Firmicutes,4HB6P@91061|Bacilli,1ZCAH@1386|Bacillus 91061|Bacilli E Synthesizes selenophosphate from selenide and ATP selD - 2.7.9.3 ko:K01008 ko00450,ko01100,map00450,map01100 - R03595 RC00002,RC02878 ko00000,ko00001,ko01000,ko03016 - - - AIRS,AIRS_C k141_36440_1 1279017.AQYJ01000020_gene1211 1.23e-88 272.0 COG3135@1|root,COG3135@2|Bacteria,1MUS1@1224|Proteobacteria,1RMD5@1236|Gammaproteobacteria,4660J@72275|Alteromonadaceae 1236|Gammaproteobacteria Q protein involved in benzoate metabolism benE - - ko:K05782 - - - - ko00000,ko02000 2.A.46.1 - - BenE k141_29544_1 720554.Clocl_1197 1.62e-40 153.0 COG0557@1|root,COG0557@2|Bacteria,1TQ1G@1239|Firmicutes,247ZS@186801|Clostridia,3WGHJ@541000|Ruminococcaceae 186801|Clostridia J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs rnr - - ko:K12573 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03016,ko03019 - - - OB_RNB,RNB,S1 k141_21091_1 1242864.D187_002187 0.0002 44.3 COG0705@1|root,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,42P0V@68525|delta/epsilon subdivisions,2WJGR@28221|Deltaproteobacteria 28221|Deltaproteobacteria O PFAM Rhomboid family - - - - - - - - - - - - Rhomboid k141_21091_2 526227.Mesil_1524 6.87e-15 77.8 COG1427@1|root,COG1427@2|Bacteria,1WIAQ@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) mqnA - 4.2.1.151 ko:K11782 ko00130,ko01110,map00130,map01110 - R10666 RC03232 ko00000,ko00001,ko01000 - - - VitK2_biosynth k141_16459_1 317025.Tcr_1186 3.12e-152 457.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,1RP3T@1236|Gammaproteobacteria,45ZUZ@72273|Thiotrichales 72273|Thiotrichales G Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate - - 2.7.9.2 ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 M00173,M00374 R00199 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - PEP-utilizers,PEP-utilizers_C,PPDK_N k141_20140_1 868595.Desca_2271 3.18e-31 128.0 COG0608@1|root,COG0608@2|Bacteria,1TPXE@1239|Firmicutes,247NU@186801|Clostridia,25ZYA@186807|Peptococcaceae 186801|Clostridia L TIGRFAM single-stranded-DNA-specific exonuclease RecJ recJ - - ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1,Helicase_C k141_20140_2 177437.HRM2_11150 9.66e-25 102.0 COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,42U1F@68525|delta/epsilon subdivisions,2WQQM@28221|Deltaproteobacteria,2MK2T@213118|Desulfobacterales 28221|Deltaproteobacteria L PFAM conserved - - 2.1.1.171 ko:K08316 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - Cons_hypoth95 k141_4523_2 1116375.VEJY3_22146 2.02e-93 276.0 COG4454@1|root,COG4454@2|Bacteria,1N7A1@1224|Proteobacteria,1SE2P@1236|Gammaproteobacteria,1XV7P@135623|Vibrionales 135623|Vibrionales P Copper-binding protein cusF - - - - - - - - - - - - k141_4523_3 223926.28808646 0.0 1923.0 COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,1SP6I@1236|Gammaproteobacteria,1XUED@135623|Vibrionales 135623|Vibrionales P Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family cusA - - ko:K07787 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.6.1.4 - - ACR_tran k141_4523_4 1116375.VEJY3_22136 0.0 1041.0 COG0845@1|root,COG0845@2|Bacteria,1MVAS@1224|Proteobacteria,1RPBZ@1236|Gammaproteobacteria,1XTPW@135623|Vibrionales 135623|Vibrionales M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family cusB - - ko:K07798 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.6.1.4,8.A.1 - - CusF_Ec,HlyD_D23,HlyD_D4 k141_4523_5 1116375.VEJY3_22131 7.93e-273 753.0 COG1538@1|root,COG1538@2|Bacteria,1NW1T@1224|Proteobacteria,1RPGN@1236|Gammaproteobacteria,1XSAB@135623|Vibrionales 135623|Vibrionales MU COG1538 Outer membrane protein - - - - - - - - - - - - OEP k141_4523_6 1280001.BAOA01000022_gene625 5.45e-37 130.0 2AWZK@1|root,31NXH@2|Bacteria,1QKKW@1224|Proteobacteria,1TIRA@1236|Gammaproteobacteria,1XZHV@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_4523_7 223926.28808651 0.0 1898.0 COG0493@1|root,COG3383@1|root,COG0493@2|Bacteria,COG3383@2|Bacteria,1MU2H@1224|Proteobacteria,1SMV9@1236|Gammaproteobacteria,1Y32S@135623|Vibrionales 135623|Vibrionales C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - 1.17.1.9 ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001,ko01000 - - - Fer2_4,Fer4,Fer4_20,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,Pyr_redox_2 k141_33027_1 1294265.JCM21738_3680 1.4e-122 351.0 COG0035@1|root,COG0035@2|Bacteria,1TPMT@1239|Firmicutes,4H9Y0@91061|Bacilli,1ZASG@1386|Bacillus 91061|Bacilli F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate upp GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 ko:K00761 ko00240,ko01100,map00240,map01100 - R00966 RC00063 ko00000,ko00001,ko01000 - - iSB619.SA_RS11010 UPRTase k141_17553_1 1116375.VEJY3_06065 1.82e-98 290.0 COG2949@1|root,COG2949@2|Bacteria,1MURW@1224|Proteobacteria,1RMG7@1236|Gammaproteobacteria,1XSGW@135623|Vibrionales 135623|Vibrionales S SanA protein sanA - - ko:K03748 - - - - ko00000 - - - DUF218 k141_13026_1 1116375.VEJY3_04390 1.24e-134 388.0 COG0687@1|root,COG0687@2|Bacteria,1MUYW@1224|Proteobacteria,1RM7W@1236|Gammaproteobacteria,1XW4V@135623|Vibrionales 135623|Vibrionales E Required for the activity of the bacterial periplasmic transport system of putrescine - - - ko:K11073 ko02010,map02010 M00300 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.2 - - SBP_bac_8 k141_13026_2 1116375.VEJY3_04395 4.2e-263 722.0 COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,1RNPX@1236|Gammaproteobacteria,1XW8Y@135623|Vibrionales 135623|Vibrionales P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system potG - - ko:K11076 ko02010,map02010 M00300 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.2 - - ABC_tran,TOBE_2 k141_13026_3 1116375.VEJY3_04400 7.11e-201 558.0 COG1176@1|root,COG1176@2|Bacteria,1MVGM@1224|Proteobacteria,1RNNZ@1236|Gammaproteobacteria,1XT5D@135623|Vibrionales 135623|Vibrionales P Putrescine transporter subunit membrane component of ABC superfamily - - - ko:K11075 ko02010,map02010 M00300 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.2 - - BPD_transp_1 k141_13026_4 1116375.VEJY3_04405 7.98e-172 483.0 COG1177@1|root,COG1177@2|Bacteria,1MVC5@1224|Proteobacteria,1RQB7@1236|Gammaproteobacteria,1XV29@135623|Vibrionales 135623|Vibrionales P Binding-protein-dependent transport system inner membrane component - - - ko:K11074 ko02010,map02010 M00300 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.2 - - BPD_transp_1 k141_13026_5 1116375.VEJY3_04410 8.27e-122 348.0 COG1396@1|root,COG1396@2|Bacteria,1RCYA@1224|Proteobacteria,1S4B9@1236|Gammaproteobacteria,1XVZD@135623|Vibrionales 135623|Vibrionales K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - Cupin_2,HTH_3 k141_34321_1 315730.BcerKBAB4_2713 1.66e-30 117.0 2DD3E@1|root,2ZGB6@2|Bacteria,1W2GF@1239|Firmicutes,4HZGP@91061|Bacilli,1ZIDY@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF4825) - - - - - - - - - - - - DUF4825 k141_34321_2 218284.CCDN010000002_gene2268 1.15e-58 188.0 COG0726@1|root,COG0726@2|Bacteria,1TT1X@1239|Firmicutes,4HAQI@91061|Bacilli,1ZBYP@1386|Bacillus 91061|Bacilli G deacetylase pdaA GO:0005575,GO:0016020 - ko:K01567 - - - - ko00000,ko01000 - - - Polysacc_deac_1 k141_5927_1 218284.CCDN010000002_gene2909 6.97e-32 123.0 COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HA0V@91061|Bacilli,1ZBTK@1386|Bacillus 91061|Bacilli O Belongs to the ClpA ClpB family clpE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03697,ko:K04086 - - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,UVR k141_21100_1 1345697.M493_04040 4.43e-13 68.6 COG0664@1|root,COG0664@2|Bacteria,1V1AS@1239|Firmicutes,4HF4V@91061|Bacilli,1WE6J@129337|Geobacillus 91061|Bacilli K Cyclic nucleotide-monophosphate binding domain fnr_1 - - - - - - - - - - - HTH_Crp_2,cNMP_binding k141_21100_2 218284.CCDN010000002_gene2858 7.74e-24 100.0 COG1657@1|root,COG1657@2|Bacteria,1TRRG@1239|Firmicutes,4HA2Q@91061|Bacilli,1ZBBW@1386|Bacillus 91061|Bacilli I COG1657 Squalene cyclase sqhC - 4.2.1.137 ko:K18115 - - - - ko00000,ko01000 - - - SQHop_cyclase_C,SQHop_cyclase_N k141_29575_1 218284.CCDN010000010_gene4394 3.21e-126 382.0 COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HACY@91061|Bacilli,1ZB4C@1386|Bacillus 91061|Bacilli O Belongs to the ClpA ClpB family clpC GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 - ko:K03696 ko01100,map01100 - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N,UVR k141_34322_1 766499.C357_09244 6.32e-67 216.0 COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,2TRCI@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) gltX1 - 6.1.1.17 ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 - - - tRNA-synt_1c k141_37729_1 218284.CCDN010000009_gene4310 1.27e-57 196.0 COG1289@1|root,COG1289@2|Bacteria,1U18W@1239|Firmicutes,4IJPB@91061|Bacilli,1ZDV7@1386|Bacillus 91061|Bacilli S Fusaric acid resistance protein-like - - - - - - - - - - - - FUSC,FUSC_2 k141_10554_1 1280001.BAOA01000022_gene668 2.55e-89 274.0 COG0814@1|root,COG0814@2|Bacteria,1NSWF@1224|Proteobacteria,1SM8N@1236|Gammaproteobacteria,1XTEM@135623|Vibrionales 135623|Vibrionales U COG0814 Amino acid permeases - - - ko:K03834 - - - - ko00000,ko02000 2.A.42.1.1 - - Trp_Tyr_perm k141_2088_1 1453501.JELR01000001_gene2029 1.19e-100 303.0 COG0438@1|root,COG0438@2|Bacteria,1N9EV@1224|Proteobacteria,1RYRV@1236|Gammaproteobacteria 1236|Gammaproteobacteria M glycosyl transferase group 1 gt4G - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 k141_17581_1 1231185.BAMP01000014_gene1714 2.29e-88 277.0 COG0520@1|root,COG0520@2|Bacteria,1N124@1224|Proteobacteria,2TZXB@28211|Alphaproteobacteria,43NNG@69277|Phyllobacteriaceae 28211|Alphaproteobacteria E COG0520 Selenocysteine lyase - - - - - - - - - - - - Aminotran_5 k141_35638_1 218284.CCDN010000008_gene4167 8.53e-110 321.0 COG3393@1|root,COG3393@2|Bacteria,1UFJG@1239|Firmicutes,4HGNR@91061|Bacilli,1ZEBH@1386|Bacillus 91061|Bacilli S GNAT acetyltransferase - - - ko:K06976 - - - - ko00000 - - - Acetyltransf_10,Acetyltransf_9,GNAT_acetyltran k141_1180_1 223926.28805454 1.42e-305 860.0 COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,1RPIU@1236|Gammaproteobacteria,1XSNU@135623|Vibrionales 135623|Vibrionales F Carbamoyl-phosphate synthetase ammonia chain carB GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0034641,GO:0034654,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046390,GO:0046394,GO:0046483,GO:0055086,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS k141_24869_1 1453501.JELR01000002_gene212 5.9e-98 290.0 COG3300@1|root,COG3300@2|Bacteria,1QUST@1224|Proteobacteria,1S7RZ@1236|Gammaproteobacteria,46877@72275|Alteromonadaceae 1236|Gammaproteobacteria T Bacterial signalling protein N terminal repeat - - - - - - - - - - - - MHYT k141_24869_2 1042377.AFPJ01000052_gene1528 2.47e-44 147.0 2EIS4@1|root,33CHF@2|Bacteria,1NI1D@1224|Proteobacteria,1SGX0@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_29576_1 218284.CCDN010000002_gene2000 2.96e-151 443.0 COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,4HA1D@91061|Bacilli,1ZATN@1386|Bacillus 91061|Bacilli L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA ligA GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - - BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5 k141_20156_1 218284.CCDN010000007_gene3902 2.79e-119 343.0 COG2364@1|root,COG2364@2|Bacteria,1V47R@1239|Firmicutes,4HGYQ@91061|Bacilli,1ZG36@1386|Bacillus 91061|Bacilli S membrane yczE GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008897,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016780,GO:0019752,GO:0019878,GO:0043436,GO:0043900,GO:0043902,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0065007,GO:0071704,GO:1900190,GO:1900192,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - ko:K07149 - - - - ko00000 - - - YitT_membrane k141_2089_1 1173024.KI912153_gene212 9.03e-65 212.0 COG2308@1|root,COG2308@2|Bacteria 2|Bacteria S glutamate-cysteine ligase activity - - - - - - - - - - - - - k141_34323_1 265729.GS18_0221265 3.22e-136 390.0 2DBF3@1|root,2Z8WF@2|Bacteria,1V133@1239|Firmicutes,4HGRP@91061|Bacilli,1ZR5P@1386|Bacillus 91061|Bacilli S Putative zinc-finger - - - - - - - - - - - - zf-HC2 k141_5929_1 240302.BN982_02542 3.77e-105 325.0 COG3711@1|root,COG3711@2|Bacteria,1TQT1@1239|Firmicutes,4HABH@91061|Bacilli,3NEA7@45667|Halobacillus 91061|Bacilli K Mga helix-turn-helix domain mtlR - - ko:K03483 - - - - ko00000,ko03000 - - - HTH_11,Mga,PRD,PTS_EIIA_2,PTS_IIB k141_1181_1 1280950.HJO_04105 2.86e-39 135.0 COG0457@1|root,COG0457@2|Bacteria,1N9D5@1224|Proteobacteria,2UIQ4@28211|Alphaproteobacteria,43YUT@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - - k141_3324_1 203122.Sde_2272 7.03e-25 102.0 COG5297@1|root,COG5297@2|Bacteria,1R47A@1224|Proteobacteria,1RREU@1236|Gammaproteobacteria,465M0@72275|Alteromonadaceae 1236|Gammaproteobacteria G Glycosyl hydrolases family 6 cel6A - 3.2.1.91 ko:K19668 ko00500,ko01100,ko02020,map00500,map01100,map02020 - R02886,R11308 RC00799 ko00000,ko00001,ko01000 - GH6 - CBM_10,CBM_2,Glyco_hydro_6,PKD k141_3324_2 1123054.KB907712_gene440 2.62e-06 49.3 COG0738@1|root,COG0738@2|Bacteria,1MXDC@1224|Proteobacteria,1RQX9@1236|Gammaproteobacteria 1236|Gammaproteobacteria G transporter gluP - - ko:K02429 - - - - ko00000,ko02000 2.A.1.7 - - MFS_1 k141_37730_1 1128421.JAGA01000001_gene2128 1.92e-30 108.0 2BWQN@1|root,347D7@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k141_37730_2 985053.VMUT_0006 1.73e-22 102.0 COG1680@1|root,arCOG00771@2157|Archaea,2XQ49@28889|Crenarchaeota 28889|Crenarchaeota E Beta-lactamase - - - - - - - - - - - - Beta-lactamase,Pab87_oct k141_13040_1 398579.Spea_3286 8.37e-20 84.0 2EAIM@1|root,334MN@2|Bacteria,1N6XM@1224|Proteobacteria,1SF6C@1236|Gammaproteobacteria,2QCJS@267890|Shewanellaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_10556_1 218284.CCDN010000008_gene4243 2.03e-180 508.0 COG0123@1|root,COG0123@2|Bacteria,1TQF7@1239|Firmicutes,4HBTF@91061|Bacilli,1ZC2K@1386|Bacillus 91061|Bacilli BQ histone deacetylase acuC - - ko:K04768 - - - - ko00000 - - iYO844.BSU29710 Hist_deacetyl k141_21101_1 1279017.AQYJ01000020_gene1321 5.51e-125 370.0 COG2114@1|root,COG2114@2|Bacteria,1N41U@1224|Proteobacteria,1SB9D@1236|Gammaproteobacteria,469AN@72275|Alteromonadaceae 1236|Gammaproteobacteria T Pfam Adenylate and Guanylate cyclase catalytic domain - - - - - - - - - - - - - k141_31613_1 1280001.BAOA01000078_gene3134 3.46e-141 400.0 COG0398@1|root,COG0398@2|Bacteria,1MVF3@1224|Proteobacteria,1RSK1@1236|Gammaproteobacteria,1XVGB@135623|Vibrionales 135623|Vibrionales S SNARE associated Golgi protein - - - - - - - - - - - - SNARE_assoc k141_31613_3 1280001.BAOA01000078_gene3136 3.92e-269 746.0 COG4135@1|root,COG4135@2|Bacteria,1MV6R@1224|Proteobacteria,1RR4B@1236|Gammaproteobacteria,1XSNA@135623|Vibrionales 135623|Vibrionales P transport system, permease component - - - ko:K05778 - M00192 - - ko00000,ko00002,ko02000 - - - BPD_transp_1 k141_24871_1 1461580.CCAS010000003_gene448 4.12e-65 214.0 COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HACS@91061|Bacilli,1ZATG@1386|Bacillus 91061|Bacilli IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - - - - - - - - - - AMP-binding,AMP-binding_C k141_24871_2 1131730.BAVI_12264 2.12e-11 64.3 COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,4HADT@91061|Bacilli,1ZAZA@1386|Bacillus 91061|Bacilli KT Transcriptional regulator - - - - - - - - - - - - CBS,HTH_8,PAS,PAS_9,Sigma54_activat k141_20157_1 1279017.AQYJ01000022_gene2667 3.51e-78 234.0 COG0824@1|root,COG0824@2|Bacteria,1MZH6@1224|Proteobacteria,1S93F@1236|Gammaproteobacteria,46841@72275|Alteromonadaceae 1236|Gammaproteobacteria S thioesterase ybgC GO:0003674,GO:0003824,GO:0016787,GO:0016788,GO:0016790 3.1.2.23 ko:K01075,ko:K07107 ko00130,ko00362,ko01100,ko01110,ko01120,map00130,map00362,map01100,map01110,map01120 - R01301 RC00004,RC00174 ko00000,ko00001,ko01000 - - iECP_1309.ECP_0747,iSDY_1059.SDY_0684 4HBT k141_35640_1 218284.CCDN010000005_gene3275 1.08e-71 222.0 COG5504@1|root,COG5504@2|Bacteria,1UYP6@1239|Firmicutes,4HFSY@91061|Bacilli,1ZCYK@1386|Bacillus 91061|Bacilli O Zn-dependent protease yjaZ - - - - - - - - - - - DUF2268 k141_5931_1 378806.STAUR_8044 6.77e-57 191.0 COG0160@1|root,COG0160@2|Bacteria,1MWY6@1224|Proteobacteria,42MB7@68525|delta/epsilon subdivisions,2WJVU@28221|Deltaproteobacteria,2YWB2@29|Myxococcales 28221|Deltaproteobacteria H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - 2.6.1.19,2.6.1.22 ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 M00027 R00908,R01648,R04188 RC00006,RC00062,RC00160 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 k141_3325_1 926569.ANT_08710 1.89e-42 153.0 COG0358@1|root,COG0358@2|Bacteria,2G65X@200795|Chloroflexi 200795|Chloroflexi L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG - - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2 k141_20158_1 1042377.AFPJ01000037_gene2839 2.23e-09 57.4 COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,1RNDC@1236|Gammaproteobacteria,464FH@72275|Alteromonadaceae 1236|Gammaproteobacteria J Tryptophanyl-tRNA synthetase trpS - 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1b k141_20158_2 1453501.JELR01000001_gene2004 3.64e-48 163.0 COG0668@1|root,COG0668@2|Bacteria,1N596@1224|Proteobacteria,1RQZP@1236|Gammaproteobacteria,465C6@72275|Alteromonadaceae 1236|Gammaproteobacteria M Mechanosensitive ion channel - - - - - - - - - - - - MS_channel k141_29580_1 218284.CCDN010000002_gene2933 1.06e-124 358.0 COG1028@1|root,COG1028@2|Bacteria,1TRVE@1239|Firmicutes,4HCFY@91061|Bacilli,1ZAXT@1386|Bacillus 91061|Bacilli IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) fabL GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.3.1.104 ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00083 R01404,R04430,R04725,R04956,R04959,R04962,R04967,R04970 RC00052,RC00076,RC00120 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 k141_21102_1 649747.HMPREF0083_00358 9.77e-35 125.0 COG0218@1|root,COG0218@2|Bacteria,1TSPW@1239|Firmicutes,4HBXZ@91061|Bacilli,26RHP@186822|Paenibacillaceae 91061|Bacilli D Necessary for normal cell division and for the maintenance of normal septation engB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K03978 - - - - ko00000,ko03036 - - - MMR_HSR1 k141_21102_2 195103.CPF_1646 1.06e-12 68.9 COG1219@1|root,COG1219@2|Bacteria,1TQ00@1239|Firmicutes,2481T@186801|Clostridia,36EA3@31979|Clostridiaceae 186801|Clostridia O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP clpX - - ko:K03544 ko04112,map04112 - - - ko00000,ko00001,ko03110 - - - AAA_2,ClpB_D2-small,zf-C4_ClpX k141_24872_1 1279017.AQYJ01000029_gene3852 8.33e-84 254.0 COG1595@1|root,COG1595@2|Bacteria,1RHKM@1224|Proteobacteria,1S48U@1236|Gammaproteobacteria,46B93@72275|Alteromonadaceae 1236|Gammaproteobacteria K Sigma-70, region 4 rpoE - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_37731_1 565653.EGBG_01946 1.09e-51 176.0 COG3935@1|root,COG3935@2|Bacteria,1V99B@1239|Firmicutes,4HK5M@91061|Bacilli,4B2HR@81852|Enterococcaceae 91061|Bacilli L DnaD domain protein - - - - - - - - - - - - DnaB_2 k141_35641_1 218284.CCDN010000002_gene2574 1.81e-106 317.0 COG0531@1|root,COG0531@2|Bacteria,1UIWG@1239|Firmicutes,4ISUQ@91061|Bacilli,1ZS6D@1386|Bacillus 91061|Bacilli E Spore germination protein - - - - - - - - - - - - Spore_permease k141_2091_2 218284.CCDN010000011_gene4411 1.39e-36 124.0 28VF7@1|root,2ZHHS@2|Bacteria,1W30J@1239|Firmicutes,4I07C@91061|Bacilli,1ZJ43@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF4305) - - - - - - - - - - - - DUF4305 k141_5933_1 42565.FP66_05895 4.58e-153 432.0 COG3186@1|root,COG3186@2|Bacteria,1MU29@1224|Proteobacteria,1RQBJ@1236|Gammaproteobacteria,1XIAP@135619|Oceanospirillales 135619|Oceanospirillales E catalyzes the formation of 4a-hydroxytetrahydrobiopterin and tyrosine from phenylalanine and tetrahydrobiopterin phhA - 1.14.16.1 ko:K00500 ko00360,ko00400,ko00790,ko01100,ko01230,map00360,map00400,map00790,map01100,map01230 - R01795,R07211 RC00490 ko00000,ko00001,ko01000 - - - Biopterin_H k141_35642_1 42565.FP66_07845 5.6e-103 311.0 COG0651@1|root,COG0651@2|Bacteria,1MURB@1224|Proteobacteria,1RQBG@1236|Gammaproteobacteria,1XHIC@135619|Oceanospirillales 135619|Oceanospirillales CP Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit mnhD - - ko:K05561 - - - - ko00000,ko02000 2.A.63.1 - - Proton_antipo_M k141_10557_1 1166948.JPZL01000002_gene1100 3.94e-38 131.0 COG1826@1|root,COG1826@2|Bacteria,1N73F@1224|Proteobacteria,1SD9K@1236|Gammaproteobacteria,1XM56@135619|Oceanospirillales 135619|Oceanospirillales U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation tatB - - ko:K03117 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - MttA_Hcf106 k141_10557_2 42565.FP66_07175 2.39e-44 144.0 COG1826@1|root,COG1826@2|Bacteria,1N6S4@1224|Proteobacteria,1SCC7@1236|Gammaproteobacteria,1XM7C@135619|Oceanospirillales 135619|Oceanospirillales U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system tatA - - ko:K03116 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - MttA_Hcf106 k141_10557_3 42565.FP66_07170 1.18e-70 213.0 COG0140@1|root,COG0140@2|Bacteria,1MZEE@1224|Proteobacteria,1S8R4@1236|Gammaproteobacteria,1XKTK@135619|Oceanospirillales 135619|Oceanospirillales E Phosphoribosyl-ATP hisE - 3.6.1.31 ko:K01523 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035 RC00002 ko00000,ko00001,ko00002,ko01000 - - - PRA-PH k141_10557_4 42565.FP66_07165 3.42e-39 143.0 COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,1RNQM@1236|Gammaproteobacteria,1XICK@135619|Oceanospirillales 135619|Oceanospirillales S Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis ubiB - - ko:K03688 - - - - ko00000 - - - ABC1 k141_16478_1 1116375.VEJY3_05025 5.89e-103 312.0 COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,1RMJ1@1236|Gammaproteobacteria,1XTXF@135623|Vibrionales 135623|Vibrionales L Belongs to the 'phage' integrase family - - - - - - - - - - - - Arm-DNA-bind_3,Phage_int_SAM_3,Phage_integrase k141_16478_3 1116375.VEJY3_05015 1.61e-284 779.0 COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,1RMJ1@1236|Gammaproteobacteria,1XTXF@135623|Vibrionales 135623|Vibrionales L Belongs to the 'phage' integrase family - - - - - - - - - - - - Arm-DNA-bind_3,Phage_int_SAM_3,Phage_integrase k141_3326_2 218284.CCDN010000001_gene55 1.65e-71 220.0 COG0284@1|root,COG0284@2|Bacteria,1TPPH@1239|Firmicutes,4HAJ2@91061|Bacilli,1ZB1I@1386|Bacillus 91061|Bacilli F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) pyrF GO:0003674,GO:0003824,GO:0004590,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 ko:K01591 ko00240,ko01100,map00240,map01100 M00051 R00965 RC00409 ko00000,ko00001,ko00002,ko01000 - - - OMPdecase k141_24873_1 218284.CCDN010000001_gene1866 1.33e-153 437.0 COG4603@1|root,COG4603@2|Bacteria,1TP1F@1239|Firmicutes,4H9VE@91061|Bacilli,1ZCTP@1386|Bacillus 91061|Bacilli S Belongs to the binding-protein-dependent transport system permease family yufP GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015749,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0034219,GO:0044425,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 - ko:K02057 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - BPD_transp_2 k141_29582_1 1294265.JCM21738_2573 1.78e-138 397.0 COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,4HA4E@91061|Bacilli,1ZB72@1386|Bacillus 91061|Bacilli P Belongs to the ABC transporter superfamily appD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02031 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - ABC_tran,oligo_HPY k141_4548_2 1279017.AQYJ01000029_gene3770 6.24e-176 498.0 COG0564@1|root,COG0564@2|Bacteria,1MVDX@1224|Proteobacteria,1RPAN@1236|Gammaproteobacteria,464VS@72275|Alteromonadaceae 1236|Gammaproteobacteria J Responsible for synthesis of pseudouridine from uracil rluC GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.24 ko:K06179 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 k141_4548_3 1042377.AFPJ01000009_gene181 2.08e-116 337.0 COG0546@1|root,COG0546@2|Bacteria,1RDA7@1224|Proteobacteria,1S3T3@1236|Gammaproteobacteria,4674R@72275|Alteromonadaceae 1236|Gammaproteobacteria S Hydrolase gph - 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 - R01334 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 k141_15529_2 1243664.CAVL020000023_gene1080 1.94e-14 74.3 2B68X@1|root,31Z68@2|Bacteria,1V93N@1239|Firmicutes,4HIJ8@91061|Bacilli,1ZFXK@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_2442_2 1042377.AFPJ01000019_gene2536 4.3e-297 818.0 COG1288@1|root,COG1288@2|Bacteria,1MY1J@1224|Proteobacteria,1RS2M@1236|Gammaproteobacteria,4657Q@72275|Alteromonadaceae 1236|Gammaproteobacteria S membrane - - - - - - - - - - - - DcuC k141_30976_1 218284.CCDN010000001_gene1884 1.98e-87 265.0 COG0196@1|root,COG0196@2|Bacteria,1TPKS@1239|Firmicutes,4H9KE@91061|Bacilli,1ZBFH@1386|Bacillus 91061|Bacilli H Belongs to the ribF family ribF - 2.7.1.26,2.7.7.2 ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS06310 FAD_syn,Flavokinase k141_25000_2 218284.CCDN010000002_gene2111 3.14e-225 625.0 COG0079@1|root,COG0079@2|Bacteria,1TPUV@1239|Firmicutes,4HA1H@91061|Bacilli,1ZBYJ@1386|Bacillus 91061|Bacilli E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily hisC - 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k141_22650_1 218284.CCDN010000001_gene205 5.87e-48 171.0 2E0HP@1|root,32W3F@2|Bacteria,1VAMS@1239|Firmicutes,4HNFF@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - k141_28597_1 1279017.AQYJ01000028_gene2179 4.06e-186 519.0 COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,1RMVK@1236|Gammaproteobacteria,4655B@72275|Alteromonadaceae 1236|Gammaproteobacteria M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins lgt GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009058,GO:0009059,GO:0009898,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0019538,GO:0031224,GO:0031226,GO:0034645,GO:0036211,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0140096,GO:1901564,GO:1901566,GO:1901576 - ko:K13292 - - - - ko00000,ko01000 - - - LGT k141_28597_2 1042377.AFPJ01000024_gene800 5.42e-189 526.0 COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria,1RPYV@1236|Gammaproteobacteria,464KC@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis thyA - 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 - - - Thymidylat_synt k141_28597_3 1042377.AFPJ01000024_gene799 8.08e-81 243.0 COG0262@1|root,COG0262@2|Bacteria,1RH0P@1224|Proteobacteria,1S5VH@1236|Gammaproteobacteria,4678W@72275|Alteromonadaceae 1236|Gammaproteobacteria H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis folA GO:0000166,GO:0003674,GO:0003824,GO:0004146,GO:0005488,GO:0005542,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008144,GO:0008150,GO:0008152,GO:0016491,GO:0016645,GO:0016646,GO:0019842,GO:0031406,GO:0033218,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050661,GO:0050662,GO:0050896,GO:0051870,GO:0051871,GO:0055114,GO:0070401,GO:0070402,GO:0072341,GO:0097159,GO:1901265,GO:1901363 1.5.1.3 ko:K00287,ko:K18590 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 M00126,M00840 R00936,R00937,R00939,R00940,R02235,R02236,R11765 RC00109,RC00110,RC00158 br01600,ko00000,ko00001,ko00002,ko01000,ko01504 - - iECBD_1354.ECBD_3567,iECDH1ME8569_1439.ECDH1ME8569_0047,iECNA114_1301.ECNA114_0036,iEcDH1_1363.EcDH1_3551,iEcSMS35_1347.EcSMS35_0050,iG2583_1286.G2583_0050,iJN746.PP_5132,iNRG857_1313.NRG857_00250,iUMN146_1321.UM146_23020 DHFR_1 k141_28597_6 1279017.AQYJ01000028_gene2184 2.11e-106 308.0 COG0811@1|root,COG0811@2|Bacteria,1MX60@1224|Proteobacteria,1RRX1@1236|Gammaproteobacteria,466VW@72275|Alteromonadaceae 1236|Gammaproteobacteria U MotA/TolQ/ExbB proton channel family - - - ko:K03561 - - - - ko00000,ko02000 1.A.30.2.1 - - MotA_ExbB k141_28597_7 1453501.JELR01000002_gene672 3.33e-76 229.0 COG0848@1|root,COG0848@2|Bacteria,1RI4M@1224|Proteobacteria,1S7FH@1236|Gammaproteobacteria,46CRR@72275|Alteromonadaceae 1236|Gammaproteobacteria U Biopolymer transport protein ExbD/TolR - - - ko:K03559 - - - - ko00000,ko02000 1.A.30.2.1 - - ExbD k141_28597_8 1453501.JELR01000002_gene671 2.4e-116 336.0 COG0810@1|root,COG0810@2|Bacteria,1PEDH@1224|Proteobacteria,1RRNT@1236|Gammaproteobacteria,464BN@72275|Alteromonadaceae 1236|Gammaproteobacteria M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - ko:K03832 - - - - ko00000,ko02000 2.C.1.1 - - TonB_C k141_28597_9 1042377.AFPJ01000024_gene793 2.89e-236 659.0 COG0457@1|root,COG0457@2|Bacteria,1MVCA@1224|Proteobacteria,1RS02@1236|Gammaproteobacteria,464BM@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0457 FOG TPR repeat - - - - - - - - - - - - ANAPC3,TPR_16,TPR_8 k141_28597_10 1279017.AQYJ01000028_gene2188 1.07e-57 188.0 COG0810@1|root,COG0810@2|Bacteria,1PEDH@1224|Proteobacteria,1RRNT@1236|Gammaproteobacteria 1236|Gammaproteobacteria U Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - ko:K03832 - - - - ko00000,ko02000 2.C.1.1 - - TonB_C k141_8401_1 218284.CCDN010000001_gene299 8.38e-131 385.0 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4HBS1@91061|Bacilli,1ZBYW@1386|Bacillus 91061|Bacilli C Aldehyde dehydrogenase family - - - - - - - - - - - - Aldedh k141_7165_1 1121921.KB898706_gene3064 5.58e-207 613.0 COG3866@1|root,COG3866@2|Bacteria,1QPFF@1224|Proteobacteria,1RQEM@1236|Gammaproteobacteria,2PMMI@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria G Amb_all pel1C - - - - - - - - - - - CBM_35,CBM_5_12_2,CBM_6,Pec_lyase_C,RicinB_lectin_2 k141_34526_1 1196031.ALEG01000033_gene3009 1.95e-21 94.7 COG1680@1|root,COG1680@2|Bacteria,1U828@1239|Firmicutes,4HA0Q@91061|Bacilli,1ZBJ0@1386|Bacillus 91061|Bacilli V Belongs to the UPF0214 family estB - 3.4.16.4 ko:K21469 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - Beta-lactamase,Peptidase_M6 k141_2443_2 1340434.AXVA01000003_gene2258 1.4e-45 155.0 COG2102@1|root,COG2102@2|Bacteria,1V5G8@1239|Firmicutes,4IS0Z@91061|Bacilli,1ZS02@1386|Bacillus 91061|Bacilli S Diphthamide synthase - - - - - - - - - - - - Diphthami_syn_2 k141_4826_1 118163.Ple7327_2558 8.27e-67 213.0 COG0457@1|root,COG0457@2|Bacteria,1G2CI@1117|Cyanobacteria,3VNEC@52604|Pleurocapsales 1117|Cyanobacteria S Sulfotransferase family - - - - - - - - - - - - Sulfotransfer_1,Sulfotransfer_3 k141_1215_2 218284.CCDN010000001_gene1398 5.23e-74 223.0 COG4326@1|root,COG4326@2|Bacteria,1UBJH@1239|Firmicutes,4IMZA@91061|Bacilli,1ZIXE@1386|Bacillus 91061|Bacilli S SpoOM protein - - - - - - - - - - - - Spo0M k141_28598_2 1294265.JCM21738_2275 1.02e-153 433.0 COG2116@1|root,COG2116@2|Bacteria,1TRTT@1239|Firmicutes,4HC15@91061|Bacilli,1ZDNX@1386|Bacillus 91061|Bacilli P Formate/nitrite transporter - - - ko:K02598 - - - - ko00000,ko02000 1.A.16.3 - - Form_Nir_trans k141_21465_1 218284.CCDN010000001_gene1974 2.29e-126 365.0 COG1175@1|root,COG1175@2|Bacteria,1TP1Q@1239|Firmicutes,4HCFJ@91061|Bacilli,1ZDIC@1386|Bacillus 91061|Bacilli G Binding-protein-dependent transport system inner membrane component amyD1 - - ko:K10118 ko02010,map02010 M00196 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.28 - - BPD_transp_1 k141_26220_1 1294265.JCM21738_1679 8.97e-22 91.7 COG2070@1|root,COG2070@2|Bacteria,1TT5U@1239|Firmicutes,4HCS7@91061|Bacilli,1ZDJD@1386|Bacillus 91061|Bacilli S Nitronate monooxygenase - - 1.13.12.16 ko:K00459 ko00910,map00910 - R00025 RC02541,RC02759 ko00000,ko00001,ko01000 - - - NMO k141_17902_1 218284.CCDN010000001_gene198 3.76e-160 458.0 COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,4HA13@91061|Bacilli,1ZAWQ@1386|Bacillus 91061|Bacilli E Aminotransferase patA - - ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 M00525 R04467 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k141_2444_1 218284.CCDN010000007_gene3813 8.3e-84 255.0 COG4241@1|root,COG4241@2|Bacteria,1UZYE@1239|Firmicutes,4HAFH@91061|Bacilli,1ZC1B@1386|Bacillus 91061|Bacilli S membrane yybS - - - - - - - - - - - DUF2232 k141_7166_1 1227349.C170_00934 5.48e-46 161.0 COG4408@1|root,COG4408@2|Bacteria,1V010@1239|Firmicutes,4HFD3@91061|Bacilli,26QQW@186822|Paenibacillaceae 91061|Bacilli S Staphylopine dehydrogenase - - - - - - - - - - - - Staph_opine_DH k141_7166_2 525378.HMPREF0793_0956 1.2e-26 105.0 COG1064@1|root,COG1064@2|Bacteria,1V5DW@1239|Firmicutes,4HH8G@91061|Bacilli,4GXXX@90964|Staphylococcaceae 91061|Bacilli S alcohol dehydrogenase - - - - - - - - - - - - NAS k141_9567_2 1196095.GAPWK_0331 5.56e-41 142.0 COG0127@1|root,COG0127@2|Bacteria,1MUK5@1224|Proteobacteria,1S27C@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions rdgB GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035870,GO:0036220,GO:0036222,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0046983,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 ko:K02428 ko00230,map00230 - R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000 - - iEC55989_1330.EC55989_3247,iECO111_1330.ECO111_3702,iECSE_1348.ECSE_3222,iECW_1372.ECW_m3212,iEKO11_1354.EKO11_0774,iEcE24377_1341.EcE24377A_3298,iWFL_1372.ECW_m3212 Ham1p_like k141_74_1 935837.JAEK01000005_gene4380 3.76e-84 261.0 COG4100@1|root,COG4100@2|Bacteria,1TQ88@1239|Firmicutes,4HAF5@91061|Bacilli,1ZAXI@1386|Bacillus 91061|Bacilli P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance ynbB GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0016740,GO:0016765,GO:0016829,GO:0016846 - - - - - - - - - - Met_gamma_lyase k141_15530_2 1453501.JELR01000001_gene1893 3.37e-316 866.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,1RMT8@1236|Gammaproteobacteria,464HQ@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth guaB GO:0003674,GO:0003824,GO:0003938,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 - - iAPECO1_1312.APECO1_4018,iECABU_c1320.ECABU_c28100,iECP_1309.ECP_2510,iECSF_1327.ECSF_2349,iUTI89_1310.UTI89_C2826,ic_1306.c3027 CBS,IMPDH,NMO k141_29757_1 945550.VISI1226_19956 9.12e-95 284.0 COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,1RP4T@1236|Gammaproteobacteria,1XTFK@135623|Vibrionales 135623|Vibrionales E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily hisC GO:0000105,GO:0003674,GO:0003824,GO:0004400,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k141_29757_2 1116375.VEJY3_05570 1.06e-258 709.0 COG0131@1|root,COG0241@1|root,COG0131@2|Bacteria,COG0241@2|Bacteria,1MWBS@1224|Proteobacteria,1RPA9@1236|Gammaproteobacteria,1XSE2@135623|Vibrionales 135623|Vibrionales E Histidine biosynthesis bifunctional protein HisB hisB GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.15,4.2.1.19 ko:K01089 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R03013,R03457 RC00017,RC00932 ko00000,ko00001,ko00002,ko01000 - - - IGPD,PNK3P k141_28599_2 218284.CCDN010000001_gene934 2.12e-42 144.0 COG4940@1|root,COG4940@2|Bacteria,1VKRP@1239|Firmicutes,4HR6S@91061|Bacilli,1ZIZV@1386|Bacillus 91061|Bacilli U COG4940 Competence protein ComGF comGF - - ko:K02248 - M00429 - - ko00000,ko00002,ko02044 - - - ComGF,N_methyl k141_21467_1 913865.DOT_2319 1.13e-50 173.0 COG2220@1|root,COG2220@2|Bacteria,1TRRP@1239|Firmicutes,24AQ5@186801|Clostridia 186801|Clostridia S Beta-lactamase superfamily domain - - - - - - - - - - - - Lactamase_B_2 k141_9568_2 446470.Snas_2463 9.69e-14 72.8 COG1266@1|root,COG1266@2|Bacteria,2IAIM@201174|Actinobacteria 201174|Actinobacteria S CAAX protease self-immunity - - - - - - - - - - - - Abi k141_15531_1 1294265.JCM21738_1703 2.36e-30 110.0 COG1595@1|root,COG1595@2|Bacteria,1VFMV@1239|Firmicutes,4HPMS@91061|Bacilli,1ZFVX@1386|Bacillus 91061|Bacilli K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_15531_2 1294265.JCM21738_1702 7.39e-24 102.0 COG1277@1|root,COG1277@2|Bacteria,1TRJ8@1239|Firmicutes,4HA9I@91061|Bacilli,1ZCXM@1386|Bacillus 91061|Bacilli S ABC-type transport system involved in multi-copper enzyme maturation permease component - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - - k141_7167_1 218284.CCDN010000001_gene1370 1.63e-69 220.0 COG1215@1|root,COG1215@2|Bacteria,1TRAD@1239|Firmicutes,4HAR8@91061|Bacilli,1ZC5X@1386|Bacillus 91061|Bacilli M Glycosyl transferase family 21 - - - ko:K10211 ko00906,map00906 - R07655 RC00523 ko00000,ko00001,ko01000 - - - Glycos_transf_2 k141_33334_2 1116375.VEJY3_18401 3.84e-188 523.0 COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,1RQU2@1236|Gammaproteobacteria,1Y2HN@135623|Vibrionales 135623|Vibrionales E Branched-chain amino acid ATP-binding cassette transporter - - - ko:K01995 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C k141_33334_3 223926.28809523 0.0 1055.0 COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria,1MVU6@1224|Proteobacteria,1RNY5@1236|Gammaproteobacteria,1XT71@135623|Vibrionales 135623|Vibrionales C Electron transfer flavoprotein-ubiquinone oxidoreductase - - 1.5.5.1 ko:K00311 - - - - ko00000,ko01000 - - - ETF_QO,FAD_binding_2,NAD_binding_8 k141_33334_4 223926.28809524 1.07e-161 454.0 COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,1RN6F@1236|Gammaproteobacteria,1XUS6@135623|Vibrionales 135623|Vibrionales C COG2086 Electron transfer flavoprotein, beta subunit - - - ko:K03521 - - - - ko00000 - - - ETF k141_33334_5 1116375.VEJY3_18386 7.99e-202 561.0 COG2025@1|root,COG2025@2|Bacteria,1MUFI@1224|Proteobacteria,1RMK7@1236|Gammaproteobacteria,1XV0A@135623|Vibrionales 135623|Vibrionales C Electron transfer flavoprotein alpha subunit - - - ko:K03522 - - - - ko00000,ko04147 - - - ETF,ETF_alpha k141_33334_6 1116375.VEJY3_18376 3.66e-60 187.0 COG3805@1|root,COG3805@2|Bacteria,1N2DN@1224|Proteobacteria,1SA51@1236|Gammaproteobacteria,1XYIR@135623|Vibrionales 135623|Vibrionales Q COG3805 Aromatic ring-cleaving dioxygenase - - - ko:K10253 - - - - ko00000,ko01000 - - - DOPA_dioxygen k141_33334_7 1248232.BANQ01000026_gene58 6.8e-253 700.0 COG0402@1|root,COG0402@2|Bacteria,1MX34@1224|Proteobacteria,1RMPF@1236|Gammaproteobacteria,1XV5T@135623|Vibrionales 135623|Vibrionales F COG0402 Cytosine deaminase and related metal-dependent hydrolases codA - 3.5.4.1 ko:K01485 ko00240,ko00330,ko01100,map00240,map00330,map01100 - R00974,R01411,R02922 RC00074,RC00514,RC00809 ko00000,ko00001,ko01000 - - - Amidohydro_3 k141_33334_8 1116375.VEJY3_18346 5.12e-227 631.0 COG0477@1|root,COG2814@2|Bacteria,1MWFH@1224|Proteobacteria,1RPAT@1236|Gammaproteobacteria,1XTE4@135623|Vibrionales 1236|Gammaproteobacteria EGP of the major facilitator superfamily ynfM GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K08224 - - - - ko00000,ko02000 2.A.1.36 - - MFS_1,Sugar_tr k141_75_1 218284.CCDN010000001_gene611 2.45e-116 350.0 COG2199@1|root,COG3706@2|Bacteria,1TQIK@1239|Firmicutes,4HEDD@91061|Bacilli,1ZB59@1386|Bacillus 91061|Bacilli T COG2199 FOG GGDEF domain - - - - - - - - - - - - GAF,GAF_2,GGDEF k141_2446_2 675814.VIC_004722 1.48e-41 142.0 2AX8Y@1|root,31P7W@2|Bacteria,1QIUZ@1224|Proteobacteria,1TGQY@1236|Gammaproteobacteria,1XY8P@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - FliJ k141_21468_1 262543.Exig_1358 5.18e-62 197.0 COG1028@1|root,COG1028@2|Bacteria,1V7U7@1239|Firmicutes,4HIUT@91061|Bacilli 91061|Bacilli IQ Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short k141_21468_2 218284.CCDN010000002_gene2720 1.77e-10 57.4 COG0789@1|root,COG0789@2|Bacteria,1V3QI@1239|Firmicutes,4IPUS@91061|Bacilli,1ZREA@1386|Bacillus 91061|Bacilli K helix_turn_helix, mercury resistance - - - - - - - - - - - - MerR_1 k141_22655_1 665952.HMPREF1015_00262 6.88e-23 88.6 2ES0W@1|root,306VH@2|Bacteria,1VET3@1239|Firmicutes,4I9TK@91061|Bacilli,1ZK2C@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2759) yqgW - - - - - - - - - - - DUF2759 k141_22655_2 218284.CCDN010000001_gene811 7.08e-14 68.6 COG0491@1|root,COG0491@2|Bacteria,1V6FA@1239|Firmicutes,4HHRQ@91061|Bacilli,1ZC72@1386|Bacillus 91061|Bacilli S COG0491 Zn-dependent hydrolases, including glyoxylases yqgX - 3.1.2.6 ko:K01069 ko00620,map00620 - R01736 RC00004,RC00137 ko00000,ko00001,ko01000 - - - Lactamase_B k141_13153_1 1279017.AQYJ01000029_gene3342 4.51e-69 219.0 COG0111@1|root,COG0111@2|Bacteria,1N5TD@1224|Proteobacteria,1RMFW@1236|Gammaproteobacteria,465GC@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate pdxB GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0033711,GO:0034641,GO:0036001,GO:0036094,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.1.1.290 ko:K03473 ko00750,ko01100,map00750,map01100 M00124 R04210 RC00084 ko00000,ko00001,ko00002,ko01000 - - iZ_1308.Z3582 2-Hacid_dh,2-Hacid_dh_C,DUF3410 k141_13153_2 1279017.AQYJ01000029_gene3341 7.62e-145 416.0 COG0258@1|root,COG0258@2|Bacteria,1RAAR@1224|Proteobacteria,1RN1S@1236|Gammaproteobacteria,466M5@72275|Alteromonadaceae 1236|Gammaproteobacteria L Helix-hairpin-helix class 2 (Pol1 family) motifs exo - - - - - - - - - - - 5_3_exonuc,5_3_exonuc_N k141_32150_1 218284.CCDN010000001_gene1053 3.25e-85 254.0 COG1547@1|root,COG1547@2|Bacteria,1VBXA@1239|Firmicutes,4HMG9@91061|Bacilli,1ZH3U@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF309) ypuF - - ko:K09763 - - - - ko00000 - - - DUF309 k141_32151_1 871585.BDGL_001310 3.98e-66 214.0 COG1902@1|root,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,1RR6H@1236|Gammaproteobacteria,3NKW6@468|Moraxellaceae 1236|Gammaproteobacteria C NADH:flavin oxidoreductase / NADH oxidase family - - - - - - - - - - - - Oxidored_FMN k141_13164_1 1279017.AQYJ01000024_gene1091 1.52e-234 652.0 COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,1RPZS@1236|Gammaproteobacteria,46530@72275|Alteromonadaceae 1236|Gammaproteobacteria D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity ftsZ GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022607,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0051258,GO:0051301,GO:0065003,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03531 ko04112,map04112 - - - ko00000,ko00001,ko02048,ko03036,ko04812 - - - FtsZ_C,Tubulin k141_13164_2 1279017.AQYJ01000024_gene1090 4.67e-278 762.0 COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,1RMXY@1236|Gammaproteobacteria,464DY@72275|Alteromonadaceae 1236|Gammaproteobacteria D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring ftsA GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0030554,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363 - ko:K03590 ko04112,map04112 - - - ko00000,ko00001,ko03036,ko04812 - - - FtsA,SHS2_FTSA k141_13164_3 1279017.AQYJ01000024_gene1089 3.42e-107 317.0 COG1589@1|root,COG1589@2|Bacteria,1N0T7@1224|Proteobacteria,1S9FJ@1236|Gammaproteobacteria,467QJ@72275|Alteromonadaceae 1236|Gammaproteobacteria D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly ftsQ GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0042802,GO:0043093,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 - ko:K03589 ko04112,map04112 - - - ko00000,ko00001,ko03036 - - - FtsQ,POTRA_1 k141_13164_5 1279017.AQYJ01000024_gene1087 3.65e-176 501.0 COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,1RMQ3@1236|Gammaproteobacteria,464K0@72275|Alteromonadaceae 1236|Gammaproteobacteria M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) murG GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008194,GO:0008375,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0050511,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.4.1.227 ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 - R05032,R05662 RC00005,RC00049 ko00000,ko00001,ko01000,ko01011 - GT28 iSFV_1184.SFV_0083,iSF_1195.SF0087,iSFxv_1172.SFxv_0091,iS_1188.S0089 Glyco_tran_28_C,Glyco_transf_28 k141_13164_6 1279017.AQYJ01000024_gene1086 5.97e-211 592.0 COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,1RMIV@1236|Gammaproteobacteria,4645C@72275|Alteromonadaceae 1236|Gammaproteobacteria M Peptidoglycan polymerase that is essential for cell division ftsW GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008360,GO:0009987,GO:0015647,GO:0015648,GO:0015835,GO:0015836,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032153,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051179,GO:0051234,GO:0051301,GO:0055085,GO:0065007,GO:0065008,GO:0071702,GO:0071705,GO:0071944,GO:1901264,GO:1901505 - ko:K03588 ko04112,map04112 - - - ko00000,ko00001,ko02000,ko03036 2.A.103.1 - - FTSW_RODA_SPOVE k141_13164_7 1042377.AFPJ01000034_gene2367 5.54e-215 607.0 COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,1RP25@1236|Gammaproteobacteria,465HJ@72275|Alteromonadaceae 1236|Gammaproteobacteria M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) murD GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008764,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - iAPECO1_1312.APECO1_1898,iECNA114_1301.ECNA114_0081,iECOK1_1307.ECOK1_0089,iECP_1309.ECP_0090,iECS88_1305.ECS88_0091,iECSF_1327.ECSF_0098,iLF82_1304.LF82_1418,iNRG857_1313.NRG857_00450,iUMN146_1321.UM146_23225,iUTI89_1310.UTI89_C0097 Mur_ligase_C,Mur_ligase_M k141_13164_8 1279017.AQYJ01000024_gene1084 2.22e-237 655.0 COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,1RNIG@1236|Gammaproteobacteria,465NF@72275|Alteromonadaceae 1236|Gammaproteobacteria M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan mraY GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.8.13 ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 - R05629,R05630 RC00002,RC02753 ko00000,ko00001,ko01000,ko01011 9.B.146 - iEC042_1314.EC042_0088,iECABU_c1320.ECABU_c00920,iECED1_1282.ECED1_0088,iECH74115_1262.ECH74115_0095,iECSP_1301.ECSP_0090,iECs_1301.ECs0091,iG2583_1286.G2583_0091,iSDY_1059.SDY_0117,iZ_1308.Z0097,ic_1306.c0105 Glycos_transf_4,MraY_sig1 k141_13164_9 1279017.AQYJ01000024_gene1083 4.46e-236 660.0 COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,1RMGD@1236|Gammaproteobacteria,464UU@72275|Alteromonadaceae 1236|Gammaproteobacteria M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein murF GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008766,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0047480,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 - R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - iB21_1397.B21_00086,iEC042_1314.EC042_0087,iEC55989_1330.EC55989_0082,iECBD_1354.ECBD_3531,iECB_1328.ECB_00087,iECD_1391.ECD_00087,iECIAI1_1343.ECIAI1_0085,iECO103_1326.ECO103_0088,iECO111_1330.ECO111_0089,iECO26_1355.ECO26_0089,iECSE_1348.ECSE_0088,iECW_1372.ECW_m0085,iEKO11_1354.EKO11_3828,iEcE24377_1341.EcE24377A_0088,iEcHS_1320.EcHS_A0092,iEcolC_1368.EcolC_3571,iSBO_1134.SBO_0074,iSSON_1240.SSON_0094,iSbBS512_1146.SbBS512_E0079,iUMNK88_1353.UMNK88_86,iWFL_1372.ECW_m0085,iYL1228.KPN_00090 Mur_ligase,Mur_ligase_C,Mur_ligase_M k141_13164_11 1279017.AQYJ01000024_gene1081 0.0 951.0 COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,1RNGW@1236|Gammaproteobacteria,4650A@72275|Alteromonadaceae 1236|Gammaproteobacteria M Catalyzes cross-linking of the peptidoglycan cell wall at the division septum ftsI GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031226,GO:0031406,GO:0032153,GO:0033218,GO:0033293,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:1901363,GO:1901681 3.4.16.4 ko:K03587 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011,ko03036 - - iSSON_1240.SSON_0092 PBP_dimer,Transpeptidase k141_13164_12 1453501.JELR01000001_gene3052 1.08e-30 110.0 COG3116@1|root,COG3116@2|Bacteria 2|Bacteria D cell division ftsL GO:0000003,GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0019954,GO:0022402,GO:0022414,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0043093,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944 - ko:K03586 - - - - ko00000,ko03036 - - - FtsL k141_13164_13 1453501.JELR01000001_gene3053 4.77e-184 516.0 COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,1RM7M@1236|Gammaproteobacteria,464CX@72275|Alteromonadaceae 1236|Gammaproteobacteria J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA rsmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 ko:K03438 - - - - ko00000,ko01000,ko03009 - - - Methyltransf_5 k141_13164_14 1453501.JELR01000001_gene3054 1.42e-95 279.0 COG2001@1|root,COG2001@2|Bacteria,1RHCG@1224|Proteobacteria,1S63F@1236|Gammaproteobacteria,467E2@72275|Alteromonadaceae 1236|Gammaproteobacteria K Belongs to the MraZ family mraZ GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - ko:K03925 - - - - ko00000 - - - MraZ k141_13164_15 161528.ED21_20974 2.69e-19 89.7 COG0526@1|root,COG0526@2|Bacteria,1N81A@1224|Proteobacteria,2UGCI@28211|Alphaproteobacteria,2K7HK@204457|Sphingomonadales 204457|Sphingomonadales CO Thioredoxin-like - - - - - - - - - - - - Thioredoxin_7 k141_29775_1 1382306.JNIM01000001_gene1023 1.33e-101 320.0 COG1529@1|root,COG1529@2|Bacteria 2|Bacteria C xanthine dehydrogenase activity hcrA - 1.3.7.9 ko:K04108 ko00362,ko00627,ko01100,ko01120,ko01220,map00362,map00627,map01100,map01120,map01220 - R05316 RC00490 ko00000,ko00001,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 k141_20261_1 1385517.N800_03295 9.31e-05 49.7 COG0760@1|root,COG0760@2|Bacteria,1RDD3@1224|Proteobacteria,1S2D7@1236|Gammaproteobacteria,1X4V0@135614|Xanthomonadales 135614|Xanthomonadales G peptidylprolyl isomerase - - 5.2.1.8 ko:K03769 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_3 k141_19080_1 1453501.JELR01000002_gene985 2.22e-62 199.0 COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,1RNQK@1236|Gammaproteobacteria,466CZ@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline proC GO:0003674,GO:0003824,GO:0004735,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0017144,GO:0018130,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0055114,GO:0055129,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 - - iSBO_1134.SBO_0282,ic_1306.c0493 F420_oxidored,P5CR_dimer k141_4836_1 218284.CCDN010000001_gene969 1.99e-16 77.4 COG0142@1|root,COG0142@2|Bacteria,1TPQY@1239|Firmicutes,4HA8E@91061|Bacilli,1ZC4G@1386|Bacillus 91061|Bacilli H Belongs to the FPP GGPP synthase family ispA GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0071704,GO:1901576 2.5.1.1,2.5.1.10,2.5.1.29 ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00366 R01658,R02003,R02061 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 - - - polyprenyl_synt k141_10748_1 1002809.SSIL_0899 9.41e-252 701.0 COG0422@1|root,COG0422@2|Bacteria,1TNZ3@1239|Firmicutes,4HC0P@91061|Bacilli,26EPU@186818|Planococcaceae 91061|Bacilli H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction thiC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 ko:K03147 ko00730,ko01100,map00730,map01100 M00127 R03472 RC03251,RC03252 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU08790 ThiC-associated,ThiC_Rad_SAM k141_34552_1 644966.Tmar_1513 2e-56 193.0 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,247W7@186801|Clostridia,3WDC3@538999|Clostridiales incertae sedis 186801|Clostridia C PFAM Aldehyde dehydrogenase family aldA - 1.2.1.3,1.2.1.32,1.2.1.39,1.2.1.60,1.2.1.8,1.2.1.85,1.2.1.99 ko:K00128,ko:K00130,ko:K00146,ko:K00151,ko:K09472,ko:K10217 ko00010,ko00053,ko00071,ko00260,ko00280,ko00310,ko00330,ko00340,ko00350,ko00360,ko00362,ko00380,ko00410,ko00561,ko00620,ko00622,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00053,map00071,map00260,map00280,map00310,map00330,map00340,map00350,map00360,map00362,map00380,map00410,map00561,map00620,map00622,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130,map01220 M00038,M00135,M00136,M00533,M00555,M00569 R00264,R00631,R00710,R00904,R01752,R01986,R02536,R02549,R02565,R02566,R02678,R02762,R02940,R02957,R03283,R03869,R03889,R04065,R04418,R04506,R04903,R05050,R05237,R05238,R05286,R05353,R06366,R07417,R07418,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00254,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_22678_2 1453501.JELR01000002_gene115 2.98e-197 579.0 COG0587@1|root,COG0587@2|Bacteria,1MUE4@1224|Proteobacteria,1RQA8@1236|Gammaproteobacteria,464B5@72275|Alteromonadaceae 1236|Gammaproteobacteria L DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase dnaE2 GO:0003674,GO:0003824,GO:0003887,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K14162 - - - - ko00000,ko01000,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon k141_1224_1 33876.JNXY01000048_gene2429 3.73e-17 83.6 COG0596@1|root,COG0596@2|Bacteria,2HVJX@201174|Actinobacteria,4DHBM@85008|Micromonosporales 201174|Actinobacteria S alpha/beta hydrolase fold - - - - - - - - - - - - Abhydrolase_1 k141_35735_1 1453501.JELR01000005_gene1606 3.12e-50 166.0 2EBHR@1|root,335I6@2|Bacteria,1N8W4@1224|Proteobacteria,1SG3V@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_7179_1 109478.XP_005874625.1 1.98e-41 158.0 KOG2177@1|root,KOG2177@2759|Eukaryota,38GC9@33154|Opisthokonta,3BJB0@33208|Metazoa,3CVYR@33213|Bilateria,488HX@7711|Chordata,48Y4J@7742|Vertebrata,3J9HK@40674|Mammalia,4M1YK@9397|Chiroptera 33208|Metazoa O NHL repeat-containing protein 2 NHLRC2 GO:0002576,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0006810,GO:0006887,GO:0008150,GO:0009987,GO:0012505,GO:0016192,GO:0030141,GO:0031091,GO:0031093,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0032940,GO:0034774,GO:0043226,GO:0043227,GO:0043229,GO:0043233,GO:0044422,GO:0044424,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0046903,GO:0051179,GO:0051234,GO:0060205,GO:0070013,GO:0097708,GO:0099503 - - - - - - - - - - NHL,Thioredoxin_8 k141_2470_2 240302.BN982_03206 4.68e-13 75.5 COG1196@1|root,COG5412@1|root,COG1196@2|Bacteria,COG5412@2|Bacteria,1TQ28@1239|Firmicutes,4HCMX@91061|Bacilli,3NFV6@45667|Halobacillus 91061|Bacilli D Phage tail tape measure protein, TP901 family - - - - - - - - - - - - PhageMin_Tail k141_23825_1 218284.CCDN010000006_gene3612 3.7e-166 473.0 COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,4HAKI@91061|Bacilli,1ZAZB@1386|Bacillus 91061|Bacilli G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis eno GO:0001968,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005518,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035375,GO:0042866,GO:0043236,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0044877,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050840,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 - - - Enolase_C,Enolase_N k141_23825_2 218284.CCDN010000006_gene3613 2.44e-71 228.0 COG0696@1|root,COG0696@2|Bacteria,1TPM4@1239|Firmicutes,4HBTQ@91061|Bacilli,1ZAPE@1386|Bacillus 91061|Bacilli G Catalyzes the interconversion of 2-phosphoglycerate and gpmI GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030145,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0043937,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046537,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0050789,GO:0050793,GO:0051186,GO:0051188,GO:0055086,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.4.2.12 ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000 - - - Metalloenzyme,Phosphodiest,iPGM_N k141_15543_1 1122176.KB903546_gene955 9e-62 217.0 COG3497@1|root,COG3497@2|Bacteria,4NEKK@976|Bacteroidetes,1IQN8@117747|Sphingobacteriia 976|Bacteroidetes S Phage tail sheath C-terminal domain - - - ko:K06907 - - - - ko00000 - - - Phage_sheath_1,Phage_sheath_1C k141_15543_2 247639.MGP2080_05130 3.92e-241 702.0 COG1629@1|root,COG4774@1|root,COG1629@2|Bacteria,COG4774@2|Bacteria,1NMCN@1224|Proteobacteria,1T3JU@1236|Gammaproteobacteria,1J59M@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_13165_1 1294265.JCM21738_2875 1.98e-163 457.0 COG0664@1|root,COG0664@2|Bacteria,1V1AS@1239|Firmicutes,4HF4V@91061|Bacilli,1ZD8M@1386|Bacillus 91061|Bacilli T COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - - - - - - - - - - HTH_Crp_2,cNMP_binding k141_13166_1 586416.GZ22_01525 5.51e-48 160.0 COG0602@1|root,COG0602@2|Bacteria,1TQ58@1239|Firmicutes,4HAJ3@91061|Bacilli 91061|Bacilli H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds queE GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008144,GO:0016829,GO:0016840,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:1901681,GO:1904047 4.3.99.3 ko:K10026 ko00790,ko01100,map00790,map01100 - R10002 RC02989 ko00000,ko00001,ko01000,ko03016 - - - Fer4_12,Fer4_14,Radical_SAM k141_23978_2 935863.AWZR01000007_gene200 4.85e-86 271.0 COG0457@1|root,COG3555@1|root,COG0457@2|Bacteria,COG3555@2|Bacteria,1MXZE@1224|Proteobacteria,1S1N0@1236|Gammaproteobacteria,1X5WC@135614|Xanthomonadales 135614|Xanthomonadales O beta-hydroxylase - - - - - - - - - - - - Asp_Arg_Hydrox,TPR_16,TPR_19 k141_1375_1 1294265.JCM21738_5279 1.04e-156 445.0 COG0182@1|root,COG0182@2|Bacteria,1TPDK@1239|Firmicutes,4H9WM@91061|Bacilli,1ZCD9@1386|Bacillus 91061|Bacilli E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) mtnA - 5.3.1.23 ko:K08963 ko00270,ko01100,map00270,map01100 M00034 R04420 RC01151 ko00000,ko00001,ko00002,ko01000 - - - IF-2B k141_13323_1 717606.PaecuDRAFT_2034 1.22e-34 135.0 COG1864@1|root,COG4085@1|root,COG5492@1|root,COG1864@2|Bacteria,COG4085@2|Bacteria,COG5492@2|Bacteria,1TSI3@1239|Firmicutes,4HAWG@91061|Bacilli,26QIC@186822|Paenibacillaceae 91061|Bacilli E lipolytic protein G-D-S-L family - - - - - - - - - - - - ABC_transp_aux k141_15699_1 1333507.AUTQ01000158_gene3402 5.1e-34 133.0 COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,1RNB7@1236|Gammaproteobacteria,2Q07D@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria S metal-dependent hydrolase with the TIM-barrel fold - - - - - - - - - - - - Amidohydro_3 k141_35839_1 1294265.JCM21738_1044 1.68e-140 405.0 28HYE@1|root,2Z83V@2|Bacteria,1TSIK@1239|Firmicutes,4HEZH@91061|Bacilli,1ZFER@1386|Bacillus 91061|Bacilli - - - - - ko:K18640 - - - - ko00000,ko04812 - - - - k141_21660_1 1033734.CAET01000049_gene1602 4.87e-07 50.1 COG0629@1|root,COG0629@2|Bacteria,1V3WT@1239|Firmicutes,4HH8I@91061|Bacilli,1ZFIJ@1386|Bacillus 91061|Bacilli L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k141_21660_3 265729.GS18_0212620 4.87e-16 74.7 COG4508@1|root,COG4508@2|Bacteria,1V6PI@1239|Firmicutes,4HJBB@91061|Bacilli,1ZGXN@1386|Bacillus 91061|Bacilli S dUTPase - - - - - - - - - - - - dUTPase_2 k141_10882_2 997296.PB1_11004 8.43e-37 130.0 COG2197@1|root,COG2197@2|Bacteria,1TVTF@1239|Firmicutes,4HAJW@91061|Bacilli,1ZC1V@1386|Bacillus 91061|Bacilli T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain desR - - ko:K07693 ko02020,map02020 M00479 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg k141_32233_1 1279017.AQYJ01000026_gene36 2.37e-96 295.0 COG0008@1|root,COG0008@2|Bacteria,1MUC8@1224|Proteobacteria,1RQ7G@1236|Gammaproteobacteria,464TJ@72275|Alteromonadaceae 1236|Gammaproteobacteria J COG0008 Glutamyl- and glutaminyl-tRNA synthetases glnS GO:0003674,GO:0003824,GO:0004812,GO:0004819,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006425,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.18 ko:K01886 ko00970,ko01100,map00970,map01100 M00359,M00360 R03652 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iECIAI39_1322.ECIAI39_0637 tRNA-synt_1c,tRNA-synt_1c_C k141_33489_1 1453501.JELR01000005_gene1577 1.48e-119 368.0 COG1629@1|root,COG1629@2|Bacteria,1MV8W@1224|Proteobacteria,1RQEQ@1236|Gammaproteobacteria,46A77@72275|Alteromonadaceae 1236|Gammaproteobacteria P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec k141_15700_1 1078085.HMPREF1210_03330 2.55e-05 50.4 COG1277@1|root,COG1277@2|Bacteria,1UYUR@1239|Firmicutes,4HEAP@91061|Bacilli,26EM8@186818|Planococcaceae 91061|Bacilli S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component yxlG - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_2,ABC2_membrane_5 k141_1376_2 218284.CCDN010000002_gene2898 1.65e-72 226.0 COG0697@1|root,COG0697@2|Bacteria,1TR8G@1239|Firmicutes,4HCXB@91061|Bacilli,1ZC8D@1386|Bacillus 91061|Bacilli EG EamA-like transporter family - - - - - - - - - - - - EamA k141_7366_1 1453501.JELR01000002_gene900 5e-60 188.0 COG3518@1|root,COG3518@2|Bacteria,1RG8W@1224|Proteobacteria,1S50E@1236|Gammaproteobacteria,4697Z@72275|Alteromonadaceae 1236|Gammaproteobacteria S Gene 25-like lysozyme - - - ko:K11897 - M00334 - - ko00000,ko00002,ko02044 - - - GPW_gp25 k141_7366_2 1453501.JELR01000002_gene901 5.37e-91 280.0 COG3517@1|root,COG3517@2|Bacteria,1MU5C@1224|Proteobacteria,1RNP7@1236|Gammaproteobacteria,463ZK@72275|Alteromonadaceae 1236|Gammaproteobacteria S Type VI secretion protein, EvpB/VC_A0108, tail sheath - - - ko:K11899,ko:K11900 ko02025,map02025 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - VipB k141_27520_1 1279017.AQYJ01000023_gene3092 1.25e-70 233.0 COG0620@1|root,COG0620@2|Bacteria,1MUI9@1224|Proteobacteria,1RMBA@1236|Gammaproteobacteria,465YA@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation metE GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0032259,GO:0034641,GO:0035999,GO:0036211,GO:0042084,GO:0042085,GO:0042558,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0050667,GO:0051186,GO:0071704,GO:0140096,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - iE2348C_1286.E2348C_4130,iECO103_1326.ECO103_4334,iECO111_1330.ECO111_4657,iECO26_1355.ECO26_4756,iECW_1372.ECW_m4131,iEKO11_1354.EKO11_4528,iPC815.YPO3788,iWFL_1372.ECW_m4131 Meth_synt_1,Meth_synt_2 k141_18114_1 1453501.JELR01000002_gene212 1.33e-100 299.0 COG3300@1|root,COG3300@2|Bacteria,1QUST@1224|Proteobacteria,1S7RZ@1236|Gammaproteobacteria,46877@72275|Alteromonadaceae 1236|Gammaproteobacteria T Bacterial signalling protein N terminal repeat - - - - - - - - - - - - MHYT k141_9689_1 1405.DJ92_4457 3.25e-16 78.6 COG0151@1|root,COG0151@2|Bacteria,1UR8C@1239|Firmicutes,4IS9W@91061|Bacilli,1ZF4M@1386|Bacillus 91061|Bacilli F Biotin carboxylase - - - - - - - - - - - - ATP-grasp_4 k141_9689_2 1347086.CCBA010000039_gene4897 3.27e-40 144.0 COG0189@1|root,COG0189@2|Bacteria,1TRXK@1239|Firmicutes,4HBN0@91061|Bacilli,1ZE4C@1386|Bacillus 91061|Bacilli HJ YheC/D like ATP-grasp - - 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 - R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - ATPgrasp_YheCD,Mur_ligase_C,Mur_ligase_M k141_37022_1 221109.22778953 7.74e-47 152.0 COG2076@1|root,COG2076@2|Bacteria,1VA2G@1239|Firmicutes,4HKGV@91061|Bacilli,23KR8@182709|Oceanobacillus 91061|Bacilli P Small Multidrug Resistance protein ykkC - - ko:K18924 - M00712 - - ko00000,ko00002,ko02000 2.A.7.1.5 - - Multi_Drug_Res k141_37022_2 946235.CAER01000062_gene3495 2.08e-29 108.0 COG2076@1|root,COG2076@2|Bacteria,1VAQQ@1239|Firmicutes,4HKMP@91061|Bacilli,23KY2@182709|Oceanobacillus 91061|Bacilli P Small Multidrug Resistance protein ykkD - - ko:K18925 - M00712 - - ko00000,ko00002,ko02000 2.A.7.1.5 - - Multi_Drug_Res k141_31178_1 1348635.BBJY01000041_gene6 5.52e-60 189.0 28J1E@1|root,2Z8YB@2|Bacteria,1MWFX@1224|Proteobacteria,1S8AR@1236|Gammaproteobacteria,1XX5B@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_16845_1 665959.HMPREF1013_00002 1.06e-34 124.0 2CDA7@1|root,3090E@2|Bacteria,1U48U@1239|Firmicutes,4IMA4@91061|Bacilli,1ZJKS@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_4945_1 1211814.CAPG01000061_gene2926 1.33e-94 288.0 COG0677@1|root,COG0677@2|Bacteria,1TPXY@1239|Firmicutes,4HAFY@91061|Bacilli,1ZC93@1386|Bacillus 91061|Bacilli M Belongs to the UDP-glucose GDP-mannose dehydrogenase family - - 1.1.1.336 ko:K02472 ko00520,ko05111,map00520,map05111 - R03317 RC00291 ko00000,ko00001,ko01000 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N k141_34671_1 1453501.JELR01000001_gene2409 2.94e-73 228.0 COG3203@1|root,COG3203@2|Bacteria,1MWUN@1224|Proteobacteria,1RZ26@1236|Gammaproteobacteria,466WT@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG3203 Outer membrane protein (porin) ifcO - - - - - - - - - - - Porin_4 k141_34671_2 349521.HCH_02712 2.15e-130 384.0 COG2079@1|root,COG2079@2|Bacteria,1MUIG@1224|Proteobacteria,1RPQN@1236|Gammaproteobacteria,1XHJJ@135619|Oceanospirillales 135619|Oceanospirillales S 2-methylcitrate dehydratase prpD - 4.2.1.79 ko:K01720 ko00640,map00640 - R04424 RC01152 ko00000,ko00001,ko01000 - - - MmgE_PrpD k141_20362_1 218284.CCDN010000004_gene3063 5.96e-131 377.0 COG1597@1|root,COG1597@2|Bacteria,1TRGQ@1239|Firmicutes,4HDR5@91061|Bacilli,1ZCT6@1386|Bacillus 91061|Bacilli I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase bmrU - - - - - - - - - - - DAGK_cat k141_33493_13 1163617.SCD_n01242 1.37e-238 678.0 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2VH3Q@28216|Betaproteobacteria 28216|Betaproteobacteria F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen - - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_lgC,Ribonuc_red_lgN k141_2651_1 218284.CCDN010000001_gene1387 6.25e-87 275.0 COG2905@1|root,COG2905@2|Bacteria,1TQFI@1239|Firmicutes,4HDTM@91061|Bacilli,1ZQQC@1386|Bacillus 91061|Bacilli T Putative nucleotidyltransferase substrate binding domain - - - ko:K07182 - - - - ko00000 - - - CBS,DUF294,DUF294_C,cNMP_binding k141_1388_1 218284.CCDN010000002_gene2834 4.61e-48 159.0 COG2230@1|root,COG2230@2|Bacteria,1V4JG@1239|Firmicutes,4HH18@91061|Bacilli,1ZE3E@1386|Bacillus 91061|Bacilli M Methyltransferase - - - - - - - - - - - - CMAS,DOT1,Methyltransf_32 k141_1388_2 218284.CCDN010000002_gene2835 6.27e-33 121.0 COG1893@1|root,COG1893@2|Bacteria,1TSZ1@1239|Firmicutes,4HB4T@91061|Bacilli,1ZAU6@1386|Bacillus 91061|Bacilli H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid panE1 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 - - - ApbA,ApbA_C k141_28815_1 1042377.AFPJ01000010_gene1431 1.76e-30 107.0 2EFYT@1|root,339QZ@2|Bacteria,1NG9A@1224|Proteobacteria,1SH9T@1236|Gammaproteobacteria,469AH@72275|Alteromonadaceae 1236|Gammaproteobacteria S MFS transporter HA62_05660 - - - - - - - - - - - - k141_23989_1 686578.AFFX01000002_gene714 1.71e-08 57.8 COG1186@1|root,COG1186@2|Bacteria,1MUAW@1224|Proteobacteria,1RP9Z@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA prfB GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02836 - - - - ko00000,ko03012 - - - PCRF,RF-1 k141_23989_2 322710.Avin_10060 4.81e-32 117.0 COG0789@1|root,COG0789@2|Bacteria,1RGX6@1224|Proteobacteria,1S8ZG@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Transcriptional regulator cueR - - ko:K19591 - M00769 - - ko00000,ko00002,ko01504,ko03000 - - - MerR,MerR-DNA-bind k141_23989_3 1042377.AFPJ01000037_gene2880 8.38e-31 115.0 2EH9Y@1|root,33B1U@2|Bacteria,1NIC9@1224|Proteobacteria,1SHT9@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_8551_1 1294265.JCM21738_2663 1.64e-44 150.0 COG1028@1|root,COG1028@2|Bacteria,1TPIK@1239|Firmicutes,4HC6E@91061|Bacilli,1ZBHS@1386|Bacillus 91061|Bacilli IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 k141_10899_1 218284.CCDN010000003_gene2999 2.19e-129 391.0 COG2208@1|root,COG2208@2|Bacteria,1TQ92@1239|Firmicutes,4HB0X@91061|Bacilli,1ZAYZ@1386|Bacillus 91061|Bacilli KT stage II sporulation protein E spoIIE GO:0005575,GO:0005623,GO:0042601,GO:0042763,GO:0044464 3.1.3.16 ko:K06382 - - - - ko00000,ko01000 - - - SpoIIE k141_13340_1 530564.Psta_0082 1.6e-97 301.0 COG1233@1|root,COG1233@2|Bacteria,2IX17@203682|Planctomycetes 203682|Planctomycetes Q FAD dependent oxidoreductase - - - - - - - - - - - - Amino_oxidase k141_6299_1 935837.JAEK01000054_gene1472 5.13e-38 145.0 2CH1R@1|root,33IF5@2|Bacteria,1VMK6@1239|Firmicutes,4HZT1@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - k141_35859_1 218284.CCDN010000008_gene4146 2.55e-40 146.0 COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HACS@91061|Bacilli,1ZB6H@1386|Bacillus 91061|Bacilli H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily menE - 6.2.1.26 ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R04030 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - AMP-binding,AMP-binding_C k141_35859_2 1132442.KB889752_gene2528 4.81e-23 97.1 COG4948@1|root,COG4948@2|Bacteria,1TQMS@1239|Firmicutes,4HBMX@91061|Bacilli,1ZBMS@1386|Bacillus 91061|Bacilli H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) menC GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.2.1.113 ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R04031 RC01053 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU30780 MR_MLE_C,MR_MLE_N k141_20368_1 1294265.JCM21738_1909 4.36e-91 284.0 COG0475@1|root,COG0569@1|root,COG0475@2|Bacteria,COG0569@2|Bacteria,1TS32@1239|Firmicutes,4H9Q5@91061|Bacilli,1ZBJR@1386|Bacillus 91061|Bacilli P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family yjbQ - - ko:K03455,ko:K03499 - - - - ko00000,ko02000 2.A.37,2.A.38.1,2.A.38.4 - - Na_H_Exchanger,TrkA_C,TrkA_N k141_13341_1 218284.CCDN010000001_gene1335 6.13e-46 157.0 COG2105@1|root,COG3703@1|root,COG2105@2|Bacteria,COG3703@2|Bacteria,1V4XC@1239|Firmicutes,4HH0F@91061|Bacilli,1ZJQH@1386|Bacillus 91061|Bacilli P Gamma-glutamyl cyclotransferase, AIG2-like ykqA - - - - - - - - - - - AIG2_2,GGACT k141_3851_1 1144313.PMI10_01485 4.65e-78 251.0 COG3250@1|root,COG3250@2|Bacteria,4NESZ@976|Bacteroidetes,1HXMX@117743|Flavobacteriia,2NU3K@237|Flavobacterium 976|Bacteroidetes G Belongs to the glycosyl hydrolase 2 family - - 3.2.1.31 ko:K01195 ko00040,ko00531,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00531,map00860,map00944,map00983,map01100,map01110,map04142 M00014,M00076,M00077,M00078,M00129 R01478,R04979,R07818,R08127,R08260,R10830 RC00055,RC00171,RC00529,RC00530,RC00714,RC01251 ko00000,ko00001,ko00002,ko01000 - - - Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N k141_9703_1 1127673.GLIP_2699 1.67e-73 236.0 COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,1RPU5@1236|Gammaproteobacteria,46411@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0471 Di- and tricarboxylate transporters sdcS - - ko:K14445 - - - - ko00000,ko02000 2.A.47.1 - - Na_sulph_symp k141_19226_2 1453501.JELR01000002_gene374 3.28e-89 270.0 COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,1RM8G@1236|Gammaproteobacteria,4642K@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives folP GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042221,GO:0042364,GO:0042398,GO:0042493,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046655,GO:0046656,GO:0050896,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.15 ko:K00796 ko00790,ko01100,map00790,map01100 M00126,M00841 R03066,R03067 RC00121,RC00842 ko00000,ko00001,ko00002,ko01000 - - iECO103_1326.ECO103_3924,iPC815.YPO3501 Pterin_bind k141_22807_1 393595.ABO_2196 1.51e-85 271.0 COG3211@1|root,COG3211@2|Bacteria,1MU8T@1224|Proteobacteria,1RSM7@1236|Gammaproteobacteria,1XN64@135619|Oceanospirillales 135619|Oceanospirillales S Bacterial protein of unknown function (DUF839) - - - ko:K07093 - - - - ko00000 - - - DUF839 k141_2652_1 218284.CCDN010000001_gene1401 1.45e-100 303.0 COG0006@1|root,COG0006@2|Bacteria,1V22K@1239|Firmicutes,4HTV2@91061|Bacilli,1ZNEY@1386|Bacillus 91061|Bacilli E Metallopeptidase family M24 - - - - - - - - - - - - - k141_4960_1 218284.CCDN010000001_gene1330 1.56e-106 333.0 COG0567@1|root,COG0567@2|Bacteria,1TRDW@1239|Firmicutes,4HAUI@91061|Bacilli,1ZAX3@1386|Bacillus 91061|Bacilli C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) odhA GO:0003674,GO:0003824,GO:0004591,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016624,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045333,GO:0055114,GO:0071704,GO:0072350,GO:1902494,GO:1990204,GO:1990234 1.2.4.2 ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R00621,R01933,R01940,R03316,R08549 RC00004,RC00027,RC00627,RC02743,RC02833,RC02883 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr k141_10900_1 867903.ThesuDRAFT_01557 1.36e-31 124.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,3WCV9@538999|Clostridiales incertae sedis 186801|Clostridia V ABC transporter transmembrane region - - - ko:K18890 ko02010,map02010 M00707 - - ko00000,ko00001,ko00002,ko02000 3.A.1.106.13,3.A.1.106.5 - - ABC_membrane,ABC_tran k141_10900_2 1121890.AUDO01000007_gene2524 0.000304 46.2 COG0791@1|root,COG0791@2|Bacteria,4NE2T@976|Bacteroidetes,1HX9E@117743|Flavobacteriia,2NU0D@237|Flavobacterium 976|Bacteroidetes M Hydrolase Nlp P60 ykfC - - - - - - - - - - - NLPC_P60,SH3_3 k141_23990_1 218284.CCDN010000006_gene3636 1.06e-117 352.0 COG0457@1|root,COG0457@2|Bacteria,1UBH2@1239|Firmicutes,4HB47@91061|Bacilli,1ZD40@1386|Bacillus 91061|Bacilli S COG0457 FOG TPR repeat yvcD - - - - - - - - - - - HTH_psq,TPR_16,TPR_19,TPR_2,TPR_8 k141_9704_1 1385514.N782_02275 1.78e-65 209.0 COG1131@1|root,COG1131@2|Bacteria,1TQEV@1239|Firmicutes,4HBHF@91061|Bacilli,2Y9WF@289201|Pontibacillus 91061|Bacilli V ABC transporter ATP-binding protein yxlF - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 k141_3852_1 1307436.PBF_05173 9.86e-104 310.0 COG0381@1|root,COG0381@2|Bacteria,1TQZT@1239|Firmicutes,4HBI3@91061|Bacilli,1ZCZG@1386|Bacillus 91061|Bacilli M Belongs to the UDP-N-acetylglucosamine 2-epimerase family mnaA - 5.1.3.14 ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 M00362 R00420 RC00290 ko00000,ko00001,ko00002,ko01000,ko01005 - - iSB619.SA_RS11005 Epimerase_2 k141_18133_1 1294265.JCM21738_4715 6.91e-142 413.0 COG0477@1|root,COG2814@2|Bacteria,1VSW8@1239|Firmicutes,4HUQC@91061|Bacilli,1ZAS8@1386|Bacillus 91061|Bacilli EGP the major facilitator superfamily bmr3 - - - - - - - - - - - MFS_1 k141_20369_1 1453501.JELR01000005_gene1581 6.95e-47 171.0 COG2273@1|root,COG3488@1|root,COG2273@2|Bacteria,COG3488@2|Bacteria,1MXUW@1224|Proteobacteria,1RRXK@1236|Gammaproteobacteria,464KW@72275|Alteromonadaceae 1236|Gammaproteobacteria C Di-haem oxidoreductase, putative peroxidase - - - - - - - - - - - - CBM_6,DHOR,F5_F8_type_C,Glyco_hydro_16,Lipoprotein_15,TSP_3 k141_22808_2 1121918.ARWE01000001_gene1166 1.29e-26 112.0 COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,1MV3Z@1224|Proteobacteria,42MBC@68525|delta/epsilon subdivisions,2WIKU@28221|Deltaproteobacteria,43TN4@69541|Desulfuromonadales 28221|Deltaproteobacteria F Catalyzes the phosphorylation of D-glycero-D-manno- heptose 7-phosphate at the C-1 position to selectively form D- glycero-beta-D-manno-heptose-1,7-bisphosphate hldE GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 ko:K03272 ko00540,ko01100,map00540,map01100 M00064 R05644,R05646 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 - - iAF987.Gmet_0922 CTP_transf_like,PfkB k141_19227_1 666686.B1NLA3E_15355 5.39e-54 189.0 COG1884@1|root,COG1884@2|Bacteria,1TSVA@1239|Firmicutes,4HDE1@91061|Bacilli,1ZAVR@1386|Bacillus 91061|Bacilli I COG1884 Methylmalonyl-CoA mutase, N-terminal domain subunit mutA - 5.4.99.2 ko:K01847 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00373,M00376,M00741 R00833 RC00395 ko00000,ko00001,ko00002,ko01000 - - - MM_CoA_mutase k141_25204_1 1279017.AQYJ01000022_gene2720 1.49e-64 235.0 COG1629@1|root,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria,4652I@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec k141_337_1 1123236.KB899390_gene3501 4.37e-52 167.0 COG0605@1|root,COG0605@2|Bacteria,1MVW2@1224|Proteobacteria,1RP7X@1236|Gammaproteobacteria,4648W@72275|Alteromonadaceae 1236|Gammaproteobacteria P Destroys radicals which are normally produced within the cells and which are toxic to biological systems sodB GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1 ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 - - - ko00000,ko00001,ko01000 - - iAF1260.b1656,iAPECO1_1312.APECO1_736,iB21_1397.B21_01616,iBWG_1329.BWG_1471,iE2348C_1286.E2348C_1742,iEC042_1314.EC042_1825,iEC55989_1330.EC55989_1824,iECABU_c1320.ECABU_c19090,iECBD_1354.ECBD_1987,iECB_1328.ECB_01626,iECDH10B_1368.ECDH10B_1790,iECDH1ME8569_1439.ECDH1ME8569_1601,iECD_1391.ECD_01626,iECED1_1282.ECED1_1855,iECH74115_1262.ECH74115_2368,iECIAI1_1343.ECIAI1_1708,iECO103_1326.ECO103_1797,iECO111_1330.ECO111_2126,iECO26_1355.ECO26_2385,iECOK1_1307.ECOK1_1775,iECP_1309.ECP_1601,iECS88_1305.ECS88_1705,iECSE_1348.ECSE_1780,iECSP_1301.ECSP_2222,iECUMN_1333.ECUMN_1946,iECW_1372.ECW_m1823,iECs_1301.ECs2365,iEKO11_1354.EKO11_2118,iETEC_1333.ETEC_1691,iEcDH1_1363.EcDH1_1984,iEcE24377_1341.EcE24377A_1869,iEcHS_1320.EcHS_A1735,iEcSMS35_1347.EcSMS35_1542,iEcolC_1368.EcolC_1973,iG2583_1286.G2583_2051,iJO1366.b1656,iJR904.b1656,iLF82_1304.LF82_2148,iNRG857_1313.NRG857_08300,iSBO_1134.SBO_1475,iSDY_1059.SDY_1882,iSFV_1184.SFV_1678,iSF_1195.SF1684,iSFxv_1172.SFxv_1892,iSSON_1240.SSON_1500,iS_1188.S1816,iSbBS512_1146.SbBS512_E1853,iUMN146_1321.UM146_08870,iUMNK88_1353.UMNK88_2117,iUTI89_1310.UTI89_C1847,iWFL_1372.ECW_m1823,iY75_1357.Y75_RS08680,iZ_1308.Z2678,ic_1306.c2050 Sod_Fe_C,Sod_Fe_N k141_337_2 1123236.KB899390_gene3500 3.73e-32 123.0 COG2766@1|root,COG2766@2|Bacteria,1MVW7@1224|Proteobacteria,1RNFJ@1236|Gammaproteobacteria,463Z0@72275|Alteromonadaceae 1236|Gammaproteobacteria T PrkA family serine protein kinase yeaG GO:0003674,GO:0003824,GO:0004672,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006995,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0042594,GO:0043170,GO:0043412,GO:0043562,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0140096,GO:1901564 - ko:K07180 - - - - ko00000 - - - AAA_PrkA,PrkA k141_12173_1 1128421.JAGA01000003_gene2920 1.24e-65 219.0 COG0664@1|root,COG0664@2|Bacteria 2|Bacteria T cyclic nucleotide binding - - - ko:K01420 - - - - ko00000,ko03000 - - - HTH_Crp_2,cNMP_binding k141_26465_1 1453501.JELR01000002_gene329 1.5e-108 324.0 COG3063@1|root,COG3063@2|Bacteria,1R0M2@1224|Proteobacteria,1T4K4@1236|Gammaproteobacteria,46DCA@72275|Alteromonadaceae 1236|Gammaproteobacteria NU Tetratricopeptide repeat - - - - - - - - - - - - TPR_16,TPR_8,Transglut_core k141_22809_2 1408303.JNJJ01000020_gene4044 6.07e-12 64.3 2CKSS@1|root,32W2Q@2|Bacteria,1VB9W@1239|Firmicutes,4HMC5@91061|Bacilli,1ZHSY@1386|Bacillus 91061|Bacilli S UPF0344 protein yisL - - - - - - - - - - - DUF1516 k141_18134_1 42565.FP66_10510 2.47e-110 335.0 COG1215@1|root,COG1215@2|Bacteria,1NQ1J@1224|Proteobacteria,1RYM8@1236|Gammaproteobacteria 1236|Gammaproteobacteria M COG1215 Glycosyltransferases, probably involved in cell wall biogenesis alg8 - 2.4.1.33 ko:K19290 ko00051,map00051 - R08692 RC00005 ko00000,ko00001,ko01000,ko01003,ko02000 4.D.1.1.7,4.D.1.1.9 GT2 - Glyco_tranf_2_3 k141_21667_1 279010.BL02636 3.63e-76 235.0 COG0346@1|root,COG0346@2|Bacteria,1TQCN@1239|Firmicutes,4HAMC@91061|Bacilli,1ZAQY@1386|Bacillus 91061|Bacilli E COG0346 Lactoylglutathione lyase and related lyases ydfO - - ko:K15975 - - - - ko00000 - - - Glyoxalase k141_8552_1 1479235.KK366039_gene2990 1.86e-156 443.0 COG1131@1|root,COG1131@2|Bacteria,1RFGG@1224|Proteobacteria 1224|Proteobacteria V Pfam ABC transporter related - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_8552_2 1479235.KK366039_gene2989 9.44e-59 193.0 COG0842@1|root,COG0842@2|Bacteria,1PM1H@1224|Proteobacteria,1RUN8@1236|Gammaproteobacteria,1XQN3@135619|Oceanospirillales 135619|Oceanospirillales V ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 k141_22810_1 1042377.AFPJ01000043_gene920 2.67e-73 229.0 COG1638@1|root,COG1638@2|Bacteria,1MVHC@1224|Proteobacteria,1RPNJ@1236|Gammaproteobacteria,464A3@72275|Alteromonadaceae 1236|Gammaproteobacteria G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component - - - - - - - - - - - - DctP k141_33495_1 406124.ACPC01000047_gene1752 7.35e-144 419.0 COG1292@1|root,COG1292@2|Bacteria,1TRS6@1239|Firmicutes,4HA7U@91061|Bacilli,1ZBRN@1386|Bacillus 91061|Bacilli M Belongs to the BCCT transporter (TC 2.A.15) family - - - ko:K05020 - - - - ko00000,ko02000 2.A.15.1.1,2.A.15.1.11 - - BCCT k141_4962_1 1121930.AQXG01000004_gene2891 2.9e-27 115.0 COG0539@1|root,COG0539@2|Bacteria,4NDW9@976|Bacteroidetes,1INSH@117747|Sphingobacteriia 976|Bacteroidetes J Ribosomal protein S1 rpsA - - ko:K02945 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - S1 k141_4962_2 1121928.AUHE01000002_gene885 1.66e-21 92.8 COG0283@1|root,COG0283@2|Bacteria,2H3SI@201174|Actinobacteria,4GCWB@85026|Gordoniaceae 201174|Actinobacteria F Cytidylate kinase cmk GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0040007,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 ko:K00945 ko00240,ko01100,map00240,map01100 M00052 R00158,R00512,R01665 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Cytidylate_kin k141_22811_1 1196031.ALEG01000065_gene125 6.37e-21 89.0 COG4821@1|root,COG4821@2|Bacteria,1TQS7@1239|Firmicutes,4HCR4@91061|Bacilli,1ZAP1@1386|Bacillus 91061|Bacilli S carbohydrate derivative metabolic process - - - - - - - - - - - - SIS_2 k141_22811_2 218284.CCDN010000005_gene3486 1.4e-51 168.0 COG2188@1|root,COG2188@2|Bacteria,1UYBW@1239|Firmicutes,4HDDG@91061|Bacilli,1ZBS6@1386|Bacillus 91061|Bacilli K transcriptional yvoA - - ko:K03710 - - - - ko00000,ko03000 - - - GntR,UTRA k141_18135_1 1267580.AF6_0127 2.38e-15 71.2 COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,4HFPW@91061|Bacilli,21WV2@150247|Anoxybacillus 91061|Bacilli J Ribosomal protein L15 rplO GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02876 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27A k141_16861_1 1232410.KI421428_gene1151 4.32e-74 229.0 2AI77@1|root,318MJ@2|Bacteria,1MXJB@1224|Proteobacteria,430PU@68525|delta/epsilon subdivisions,2WW3I@28221|Deltaproteobacteria 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k141_8553_1 218284.CCDN010000006_gene3594 2.57e-144 424.0 COG0843@1|root,COG0843@2|Bacteria,1TP2U@1239|Firmicutes,4HA4X@91061|Bacilli,1ZBD5@1386|Bacillus 91061|Bacilli C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B qoxB GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009486,GO:0009987,GO:0015002,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016310,GO:0016491,GO:0016679,GO:0016682,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0034220,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0098655,GO:0098660,GO:0098662,GO:1901135,GO:1901360,GO:1901564,GO:1902600 1.10.3.12 ko:K02827 ko00190,ko01100,map00190,map01100 M00416 R09492 RC00819 ko00000,ko00001,ko00002,ko01000 3.D.4.1 - - COX1 k141_12174_1 351016.RAZWK3B_11321 1.11e-108 312.0 2AU0F@1|root,31JKB@2|Bacteria,1RGGF@1224|Proteobacteria,2U8PC@28211|Alphaproteobacteria 28211|Alphaproteobacteria S COG NOG14600 non supervised orthologous group - - - - - - - - - - - - - k141_10902_1 1453501.JELR01000001_gene2373 2.33e-117 367.0 COG1629@1|root,COG4771@2|Bacteria,1N6JG@1224|Proteobacteria,1RP10@1236|Gammaproteobacteria,465FE@72275|Alteromonadaceae 1236|Gammaproteobacteria P Carboxypeptidase regulatory-like domain - - - - - - - - - - - - CarboxypepD_reg,Plug,TonB_dep_Rec k141_7380_1 1294265.JCM21738_1162 2.41e-23 94.7 COG0500@1|root,COG2226@2|Bacteria,1V3T6@1239|Firmicutes,4HHF1@91061|Bacilli,1ZFN7@1386|Bacillus 91061|Bacilli Q Could be a S-adenosyl-L-methionine-dependent methyltransferase yrrT GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 - ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 M00609 R10404 RC00003 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_11,Methyltransf_23,Methyltransf_25 k141_7380_2 1294265.JCM21738_1163 1.45e-36 125.0 COG0745@1|root,COG0745@2|Bacteria,1UW6F@1239|Firmicutes,4I3AX@91061|Bacilli,1ZIE8@1386|Bacillus 91061|Bacilli KT cheY-homologous receiver domain - - - ko:K07775 ko02020,map02020 M00458 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg k141_2653_1 218284.CCDN010000005_gene3387 5.12e-158 452.0 COG0719@1|root,COG0719@2|Bacteria,1TQ21@1239|Firmicutes,4HA1Z@91061|Bacilli,1ZCDS@1386|Bacillus 91061|Bacilli O FeS cluster assembly sufB - - ko:K07033,ko:K09014 - - - - ko00000 - - - UPF0051 k141_2653_2 218284.CCDN010000005_gene3386 5.59e-97 282.0 COG0822@1|root,COG0822@2|Bacteria,1V3H9@1239|Firmicutes,4HIJ0@91061|Bacilli,1ZFQ8@1386|Bacillus 91061|Bacilli C COG0822 NifU homolog involved in Fe-S cluster formation nifU GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0030003,GO:0036455,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0097428,GO:0098771,GO:1901564 - ko:K04488 - - - - ko00000 - - - NifU_N k141_14518_3 1294265.JCM21738_615 2.49e-67 204.0 COG2868@1|root,COG2868@2|Bacteria,1VEQ9@1239|Firmicutes,4HNMV@91061|Bacilli,1ZI1F@1386|Bacillus 91061|Bacilli J ribosomal protein ysxB - - ko:K07584 - - - - ko00000 - - - Peptidase_Prp k141_14518_4 665959.HMPREF1013_02450 1.37e-60 186.0 COG0211@1|root,COG0211@2|Bacteria,1V6HW@1239|Firmicutes,4HIMN@91061|Bacilli,1ZGZ9@1386|Bacillus 91061|Bacilli J Belongs to the bacterial ribosomal protein bL27 family rpmA GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02899 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27 k141_14518_5 1294265.JCM21738_613 2.25e-112 323.0 COG3290@1|root,COG3290@2|Bacteria,1V8IS@1239|Firmicutes,4HQ4T@91061|Bacilli,1ZHUN@1386|Bacillus 91061|Bacilli T Sporulation initiation phospho-transferase B, C-terminal spo0B GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K06375 ko02020,ko02024,map02020,map02024 - - - ko00000,ko00001,ko01000 - - - SPOB_a,SPOB_ab k141_13370_2 1279017.AQYJ01000021_gene2900 0.0 881.0 COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,1RMYA@1236|Gammaproteobacteria,464VT@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine purF GO:0003674,GO:0003824,GO:0004044,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006520,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009117,GO:0009165,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019752,GO:0034641,GO:0034654,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 - - iAF1260.b2312,iB21_1397.B21_02197,iBWG_1329.BWG_2086,iECBD_1354.ECBD_1347,iECB_1328.ECB_02237,iECDH10B_1368.ECDH10B_2474,iECDH1ME8569_1439.ECDH1ME8569_2250,iECD_1391.ECD_02237,iECIAI1_1343.ECIAI1_2389,iECO103_1326.ECO103_2776,iECO111_1330.ECO111_3060,iECO26_1355.ECO26_3300,iECW_1372.ECW_m2501,iEKO11_1354.EKO11_1453,iETEC_1333.ETEC_2448,iEcDH1_1363.EcDH1_1344,iEcE24377_1341.EcE24377A_2606,iEcolC_1368.EcolC_1340,iJO1366.b2312,iJR904.b2312,iSF_1195.SF2388,iSFxv_1172.SFxv_2633,iSSON_1240.SSON_2370,iS_1188.S2523,iSbBS512_1146.SbBS512_E2690,iUMNK88_1353.UMNK88_2863,iWFL_1372.ECW_m2501,iY75_1357.Y75_RS12125 GATase_6,Pribosyltran k141_12423_1 1340434.AXVA01000004_gene2697 1.61e-96 285.0 28PQ5@1|root,2ZCCA@2|Bacteria,1V1RW@1239|Firmicutes,4HGAM@91061|Bacilli,1ZFQB@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2812) - - - - - - - - - - - - DUF2812 k141_12423_2 326423.RBAM_005510 6.27e-59 183.0 COG1695@1|root,COG1695@2|Bacteria,1VANP@1239|Firmicutes,4HKRZ@91061|Bacilli,1ZQHA@1386|Bacillus 91061|Bacilli K Transcriptional regulator PadR-like family - - - - - - - - - - - - PadR k141_5160_1 1122604.JONR01000015_gene196 1.99e-130 380.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RMMJ@1236|Gammaproteobacteria,1X56A@135614|Xanthomonadales 135614|Xanthomonadales I Acyl-CoA dehydrogenase - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_32390_1 1121377.KB906434_gene695 1.1e-33 137.0 COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,1WMBC@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus T AAA domain - - - - - - - - - - - - AAA_22,BTAD,TPR_12 k141_37189_1 1116375.VEJY3_17036 1.92e-64 204.0 COG0583@1|root,COG0583@2|Bacteria,1R509@1224|Proteobacteria,1RSBX@1236|Gammaproteobacteria,1XVV1@135623|Vibrionales 135623|Vibrionales K Bacterial regulatory helix-turn-helix protein, lysR family - - - ko:K03566 ko02026,map02026 - - - ko00000,ko00001,ko03000 - - - HTH_1,LysR_substrate k141_37189_2 717774.Marme_3590 1.37e-209 598.0 COG1404@1|root,COG2755@1|root,COG1404@2|Bacteria,COG2755@2|Bacteria,1QU0M@1224|Proteobacteria,1RS8Q@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Pectic acid lyase - - - - - - - - - - - - Pec_lyase k141_37189_3 1116375.VEJY3_16956 6.38e-198 549.0 COG0583@1|root,COG0583@2|Bacteria,1R81F@1224|Proteobacteria,1S0WQ@1236|Gammaproteobacteria,1XTM1@135623|Vibrionales 135623|Vibrionales K Transcriptional regulator VVA1234 - - - - - - - - - - - HTH_1,LysR_substrate k141_37189_4 1280001.BAOA01000045_gene1657 6.42e-300 818.0 COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,1RNEW@1236|Gammaproteobacteria,1XSYJ@135623|Vibrionales 135623|Vibrionales F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP VVA1235 - 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 - - - Adenylsucc_synt k141_13617_1 1453501.JELR01000001_gene2506 2.95e-51 169.0 28M8G@1|root,2ZAMM@2|Bacteria,1MVBT@1224|Proteobacteria,1RMAM@1236|Gammaproteobacteria,467EP@72275|Alteromonadaceae 1236|Gammaproteobacteria S RES - - - - - - - - - - - - RES k141_13617_2 1453501.JELR01000001_gene2507 6.99e-50 160.0 COG5642@1|root,COG5642@2|Bacteria,1N2DF@1224|Proteobacteria,1S93Q@1236|Gammaproteobacteria,4689N@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF2384) - - - - - - - - - - - - DUF2384,HTH_3 k141_14632_2 886377.Murru_2530 3.89e-86 282.0 COG1680@1|root,COG1680@2|Bacteria,4NEEP@976|Bacteroidetes,1I052@117743|Flavobacteriia 976|Bacteroidetes V Beta-lactamase class C and other penicillin binding - - - - - - - - - - - - Beta-lactamase k141_8794_2 1453501.JELR01000005_gene1622 3.54e-86 259.0 COG1376@1|root,COG1376@2|Bacteria,1Q823@1224|Proteobacteria,1S0YT@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Pfam L,D-transpeptidase catalytic domain - - - - - - - - - - - - YkuD k141_524_1 675816.VIA_002227 1.46e-72 229.0 COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,1RVZ6@1236|Gammaproteobacteria,1Y2M6@135623|Vibrionales 135623|Vibrionales H Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine - - 2.7.7.87 ko:K07566 - - R10463 RC00745 ko00000,ko01000,ko03009,ko03016 - - - SUA5,Sua5_yciO_yrdC k141_524_2 314278.NB231_15703 9.31e-231 672.0 COG3002@1|root,COG3002@2|Bacteria,1MX5K@1224|Proteobacteria,1RQC2@1236|Gammaproteobacteria,1WWPR@135613|Chromatiales 135613|Chromatiales S Belongs to the UPF0753 family - - - ko:K09822 - - - - ko00000 - - - DUF2309 k141_524_3 1122194.AUHU01000014_gene1136 7.33e-88 282.0 COG1009@1|root,COG1009@2|Bacteria,1MW9F@1224|Proteobacteria,1RN54@1236|Gammaproteobacteria,469HG@72275|Alteromonadaceae 1236|Gammaproteobacteria CP Proton-conducting membrane transporter - - 1.6.5.3 ko:K05577 ko00190,ko01100,map00190,map01100 M00145 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 - - - Proton_antipo_M,Proton_antipo_N k141_33731_1 1279017.AQYJ01000029_gene3475 1.1e-104 331.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,464D1@72275|Alteromonadaceae 1236|Gammaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K18138 ko01501,ko01503,map01501,map01503 M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2 - - ACR_tran k141_9953_1 1042377.AFPJ01000009_gene261 1.14e-08 58.9 2EG2H@1|root,339UG@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k141_35980_1 1305836.AXVE01000011_gene1147 1.13e-90 275.0 COG1957@1|root,COG1957@2|Bacteria,1TRWG@1239|Firmicutes,4HCMZ@91061|Bacilli 91061|Bacilli F nucleoside hydrolase rihA_1 - 3.2.2.1 ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 - R01245,R01273,R01677,R01770,R02143 RC00033,RC00063,RC00122,RC00318,RC00485 ko00000,ko00001,ko01000 - - - IU_nuc_hydro k141_26759_1 1453501.JELR01000002_gene387 1.08e-158 464.0 COG0515@1|root,COG0631@1|root,COG0515@2|Bacteria,COG0631@2|Bacteria,1MV1P@1224|Proteobacteria,1RNQN@1236|Gammaproteobacteria,464NH@72275|Alteromonadaceae 1236|Gammaproteobacteria T Serine threonine protein ppkB - - - - - - - - - - - PP2C_2,Pkinase k141_30022_1 1279017.AQYJ01000024_gene1033 3.23e-76 259.0 COG3164@1|root,COG3164@2|Bacteria,1MXWF@1224|Proteobacteria,1RNUK@1236|Gammaproteobacteria,464CY@72275|Alteromonadaceae 1236|Gammaproteobacteria S membrane yhdP GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0042597,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - - - - - - - - - - AsmA_2,DUF3971 k141_37191_1 1279017.AQYJ01000020_gene1212 4.63e-79 241.0 COG1802@1|root,COG1802@2|Bacteria,1RJYG@1224|Proteobacteria,1SZ8X@1236|Gammaproteobacteria,46CZ6@72275|Alteromonadaceae 1236|Gammaproteobacteria K FCD - - - - - - - - - - - - FCD,GntR k141_7490_1 1347086.CCBA010000023_gene2369 1.81e-80 244.0 COG0778@1|root,COG0778@2|Bacteria,1UB8S@1239|Firmicutes,4HEGP@91061|Bacilli,1ZDZK@1386|Bacillus 91061|Bacilli C Nitroreductase family - - 1.5.1.39 ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 - R05705,R05706,R08014,R08017,R08042 RC00126,RC00250 ko00000,ko00001,ko01000 - - - Nitroreductase k141_7490_2 1396.DJ87_2157 4.21e-19 81.6 COG3449@1|root,COG3449@2|Bacteria,1V3RQ@1239|Firmicutes,4IPKI@91061|Bacilli,1ZFWU@1386|Bacillus 91061|Bacilli L Integron-associated effector binding protein - - - - - - - - - - - - GyrI-like k141_37192_1 1042377.AFPJ01000034_gene2367 5.29e-20 88.6 COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,1RP25@1236|Gammaproteobacteria,465HJ@72275|Alteromonadaceae 1236|Gammaproteobacteria M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) murD GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008764,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - iAPECO1_1312.APECO1_1898,iECNA114_1301.ECNA114_0081,iECOK1_1307.ECOK1_0089,iECP_1309.ECP_0090,iECS88_1305.ECS88_0091,iECSF_1327.ECSF_0098,iLF82_1304.LF82_1418,iNRG857_1313.NRG857_00450,iUMN146_1321.UM146_23225,iUTI89_1310.UTI89_C0097 Mur_ligase_C,Mur_ligase_M k141_34842_1 1279017.AQYJ01000029_gene3475 0.0 1326.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,464D1@72275|Alteromonadaceae 1236|Gammaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K18138 ko01501,ko01503,map01501,map01503 M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2 - - ACR_tran k141_34842_2 1453501.JELR01000001_gene2098 2.44e-128 370.0 COG0564@1|root,COG0564@2|Bacteria,1N8GW@1224|Proteobacteria,1RMZ7@1236|Gammaproteobacteria,466SC@72275|Alteromonadaceae 1236|Gammaproteobacteria J COG0564 Pseudouridylate synthases, 23S RNA-specific truC GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.26 ko:K06175 - - - - ko00000,ko01000,ko03016 - - - PseudoU_synth_2 k141_34842_3 1279017.AQYJ01000029_gene3472 8.76e-65 199.0 COG3012@1|root,COG3012@2|Bacteria,1MZZK@1224|Proteobacteria,1S9FV@1236|Gammaproteobacteria,468GH@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria ychJ - - ko:K09858 - - - - ko00000 - - - SEC-C k141_34842_4 1042377.AFPJ01000042_gene1019 6.89e-106 313.0 COG3786@1|root,COG3786@2|Bacteria,1RH22@1224|Proteobacteria,1S2SR@1236|Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - YkuD k141_34842_5 1042377.AFPJ01000009_gene308 7.98e-78 242.0 2FEBM@1|root,346BC@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k141_34842_6 1042377.AFPJ01000009_gene307 4.24e-222 625.0 COG2866@1|root,COG2866@2|Bacteria,1R6VU@1224|Proteobacteria,1S14Z@1236|Gammaproteobacteria,466N8@72275|Alteromonadaceae 1236|Gammaproteobacteria E Zinc carboxypeptidase - - - - - - - - - - - - Peptidase_M14 k141_34842_8 1042377.AFPJ01000042_gene1018 6.43e-291 800.0 COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,1RNW9@1236|Gammaproteobacteria,464BR@72275|Alteromonadaceae 1236|Gammaproteobacteria H Aminotransferase class-III - - 2.6.1.113 ko:K12256 ko00330,ko01100,map00330,map01100 - R08714 RC00008,RC00062 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_3 k141_34842_9 1042377.AFPJ01000042_gene1017 3.76e-171 483.0 COG0583@1|root,COG0583@2|Bacteria,1MVGZ@1224|Proteobacteria,1RRFH@1236|Gammaproteobacteria,467Z1@72275|Alteromonadaceae 1236|Gammaproteobacteria K Bacterial regulatory helix-turn-helix protein, lysR family - - - - - - - - - - - - HTH_1,LysR_substrate k141_34842_10 1042377.AFPJ01000042_gene1016 0.0 1217.0 COG1629@1|root,COG4771@2|Bacteria,1QV5Q@1224|Proteobacteria,1T4RK@1236|Gammaproteobacteria,46DC8@72275|Alteromonadaceae 1236|Gammaproteobacteria P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec k141_34842_11 1042377.AFPJ01000042_gene1015 5.99e-134 402.0 COG1472@1|root,COG1472@2|Bacteria,1MVAJ@1224|Proteobacteria,1RMQF@1236|Gammaproteobacteria,465G4@72275|Alteromonadaceae 1236|Gammaproteobacteria G Beta-N-acetylhexosaminidase ybbD - 3.2.1.52 ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 M00628 R00022,R05963,R07809,R07810,R10831 RC00049 ko00000,ko00001,ko00002,ko01000 - - - Glyco_hydro_3,Glyco_hydro_3_C k141_12424_1 1307436.PBF_11287 2.08e-79 253.0 28IB3@1|root,2Z8DK@2|Bacteria,1UZH8@1239|Firmicutes,4HEHS@91061|Bacilli,1ZBKM@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - SLAC1 k141_1536_2 674977.VMC_09270 4.49e-70 214.0 2B22N@1|root,31UJJ@2|Bacteria,1QSF4@1224|Proteobacteria,1THZ8@1236|Gammaproteobacteria,1XXZ8@135623|Vibrionales 135623|Vibrionales S transcriptional regulators - - - - - - - - - - - - - k141_1536_3 1116375.VEJY3_23481 2.77e-234 648.0 COG0668@1|root,COG0668@2|Bacteria,1MXD2@1224|Proteobacteria,1RNUB@1236|Gammaproteobacteria,1XUER@135623|Vibrionales 135623|Vibrionales M COG0668 Small-conductance mechanosensitive channel ynaI - - ko:K16052 - - - - ko00000,ko02000 1.A.23.4 - - MS_channel k141_1536_4 223926.28809904 3.86e-149 422.0 COG3338@1|root,COG3338@2|Bacteria,1PEA6@1224|Proteobacteria,1RSM9@1236|Gammaproteobacteria,1XT7N@135623|Vibrionales 135623|Vibrionales P carbonic anhydrase - - 4.2.1.1 ko:K01674 ko00910,map00910 - R00132,R10092 RC02807 ko00000,ko00001,ko01000 - - - Carb_anhydrase k141_1536_5 1116375.VEJY3_23491 1.47e-100 292.0 2BA50@1|root,323IW@2|Bacteria,1RKEJ@1224|Proteobacteria,1S5X7@1236|Gammaproteobacteria,1XWY3@135623|Vibrionales 135623|Vibrionales S Domain of unknown function (DUF3859) - - - - - - - - - - - - DUF3859 k141_23065_1 1116375.VEJY3_17996 4.02e-73 228.0 COG0583@1|root,COG0583@2|Bacteria,1N4BZ@1224|Proteobacteria,1RRCD@1236|Gammaproteobacteria,1XUB7@135623|Vibrionales 135623|Vibrionales K COG0583 Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_23065_2 1116375.VEJY3_18026 1.16e-52 167.0 2A022@1|root,30N4C@2|Bacteria,1PU9F@1224|Proteobacteria,1SCMU@1236|Gammaproteobacteria,1XYCX@135623|Vibrionales 135623|Vibrionales S Domain of unknown function (DUF1840) VPA1132 - - - - - - - - - - - DUF1840 k141_23065_3 1116375.VEJY3_18036 3.19e-221 613.0 COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,1RPX5@1236|Gammaproteobacteria,1XV22@135623|Vibrionales 135623|Vibrionales C oxidoreductases (related to aryl-alcohol dehydrogenases) - - - - - - - - - - - - Aldo_ket_red k141_23065_4 1116375.VEJY3_18041 1.69e-227 626.0 COG0673@1|root,COG0673@2|Bacteria,1MXUP@1224|Proteobacteria,1RP9K@1236|Gammaproteobacteria,1XW82@135623|Vibrionales 135623|Vibrionales S Oxidoreductase family, NAD-binding Rossmann fold - - 1.1.1.312 ko:K10219 ko00350,ko00362,ko00627,ko01120,ko01220,map00350,map00362,map00627,map01120,map01220 M00533 R04278,R04279,R04418,R04419 RC00251,RC00254 ko00000,ko00001,ko00002,ko01000 - - - GFO_IDH_MocA k141_23065_5 1116375.VEJY3_18046 2.02e-182 511.0 COG2084@1|root,COG2084@2|Bacteria,1MX8V@1224|Proteobacteria,1RW94@1236|Gammaproteobacteria,1XZW3@135623|Vibrionales 135623|Vibrionales I Domain of unknown function (DUF1932) - - - - - - - - - - - - DUF1932,NAD_binding_2 k141_23065_6 1116375.VEJY3_18051 2.8e-276 757.0 COG0583@1|root,COG0583@2|Bacteria,1Q531@1224|Proteobacteria,1RWPD@1236|Gammaproteobacteria,1XYR5@135623|Vibrionales 135623|Vibrionales K Bacterial regulatory helix-turn-helix protein, lysR family - - - - - - - - - - - - HTH_1,LysR_substrate k141_23065_7 1116375.VEJY3_18056 7.14e-213 591.0 COG1638@1|root,COG1638@2|Bacteria,1NJX4@1224|Proteobacteria,1RYTI@1236|Gammaproteobacteria,1Y2J9@135623|Vibrionales 135623|Vibrionales G Bacterial extracellular solute-binding protein, family 7 - - - - - - - - - - - - DctP k141_23065_8 1116375.VEJY3_18061 2.08e-96 282.0 COG3090@1|root,COG3090@2|Bacteria,1RH2H@1224|Proteobacteria,1SYAI@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Tripartite ATP-independent periplasmic transporters, DctQ component - - - - - - - - - - - - DctQ k141_23065_9 1517681.HW45_13275 7.39e-227 634.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,1RNAM@1236|Gammaproteobacteria,1XTIW@135623|Vibrionales 135623|Vibrionales G TRAP-type C4-dicarboxylate transport system, large permease component - - - - - - - - - - - - DctM k141_23065_10 1116375.VEJY3_18071 7.73e-168 475.0 COG0679@1|root,COG0679@2|Bacteria,1PINE@1224|Proteobacteria,1S1GM@1236|Gammaproteobacteria,1XYIT@135623|Vibrionales 135623|Vibrionales S Membrane transport protein - - - ko:K07088 - - - - ko00000 - - - Mem_trans k141_23065_11 1116375.VEJY3_18076 0.0 1176.0 COG1082@1|root,COG3185@1|root,COG1082@2|Bacteria,COG3185@2|Bacteria,1MUVZ@1224|Proteobacteria,1RN2Z@1236|Gammaproteobacteria,1XW7J@135623|Vibrionales 135623|Vibrionales EG Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal - - 1.13.11.27 ko:K00457 ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100 M00044 R01372,R02521 RC00505,RC00738 ko00000,ko00001,ko00002,ko01000,ko04147 - - - AP_endonuc_2,Glyoxalase_5 k141_35981_2 1453501.JELR01000002_gene1400 1.19e-38 135.0 COG0454@1|root,COG0456@2|Bacteria,1NGUX@1224|Proteobacteria,1SV6D@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Acetyltransferase (GNAT) family - - - - - - - - - - - - - k141_8795_1 1317122.ATO12_03170 9.75e-46 158.0 COG0076@1|root,COG0076@2|Bacteria,4NGRW@976|Bacteroidetes,1HYSV@117743|Flavobacteriia,2YHXY@290174|Aquimarina 976|Bacteroidetes E Pyridoxal-dependent decarboxylase conserved domain hdc - 4.1.1.22 ko:K01590 ko00340,ko01100,ko01110,map00340,map01100,map01110 - R01167 RC00299 ko00000,ko00001,ko01000 - - - Pyridoxal_deC k141_31294_1 218284.CCDN010000001_gene52 1.57e-275 777.0 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4H9S5@91061|Bacilli,1ZCDJ@1386|Bacillus 91061|Bacilli P COG0474 Cation transport ATPase yloB GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - iYO844.BSU15650 Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase k141_20564_1 1229780.BN381_290067 2.98e-47 174.0 COG1574@1|root,COG1574@2|Bacteria,2GJVW@201174|Actinobacteria,3UXEZ@52018|unclassified Actinobacteria (class) 201174|Actinobacteria S Amidohydrolase family - - - - - - - - - - - - Amidohydro_3 k141_20564_2 443152.MDG893_16312 4.55e-108 318.0 COG1024@1|root,COG1024@2|Bacteria,1NDT7@1224|Proteobacteria,1RSCI@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Belongs to the enoyl-CoA hydratase isomerase family - - 4.2.1.17 ko:K01692 ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212 M00032,M00087 R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093 RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 k141_5162_1 1116375.VEJY3_03745 1e-312 853.0 COG3104@1|root,COG3104@2|Bacteria,1MW6W@1224|Proteobacteria,1RM8P@1236|Gammaproteobacteria,1XTDG@135623|Vibrionales 135623|Vibrionales U COG3104 Dipeptide tripeptide permease - - - ko:K03305 - - - - ko00000 2.A.17 - - PTR2 k141_25409_2 1384054.N790_04560 7.6e-11 64.3 COG4967@1|root,COG4967@2|Bacteria,1QHAU@1224|Proteobacteria,1SX42@1236|Gammaproteobacteria,1X7QT@135614|Xanthomonadales 135614|Xanthomonadales NU type IV pilus modification protein PilV - - - - - - - - - - - - N_methyl k141_37193_1 316067.Geob_0454 9.55e-97 290.0 COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,42MTF@68525|delta/epsilon subdivisions,2WJ6X@28221|Deltaproteobacteria,43T9A@69541|Desulfuromonadales 28221|Deltaproteobacteria D PFAM Cobyrinic acid a,c-diamide synthase soj - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 k141_7491_1 42565.FP66_14775 3.29e-101 315.0 COG0668@1|root,COG0668@2|Bacteria,1MY0I@1224|Proteobacteria,1RQKY@1236|Gammaproteobacteria,1XJP8@135619|Oceanospirillales 135619|Oceanospirillales M COG0668 Small-conductance mechanosensitive channel - - - ko:K22044 - - - - ko00000,ko02000 1.A.23.3 - - MS_channel k141_17043_2 1042377.AFPJ01000048_gene2678 4.09e-287 791.0 COG0527@1|root,COG0527@2|Bacteria,1MVSI@1224|Proteobacteria,1RQ37@1236|Gammaproteobacteria,4658P@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0527 Aspartokinases lysC GO:0003674,GO:0003824,GO:0004072,GO:0006082,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019491,GO:0019752,GO:0032787,GO:0042399,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,ACT_7 k141_17043_3 1453501.JELR01000002_gene497 3.2e-79 236.0 COG1917@1|root,COG1917@2|Bacteria,1RDGQ@1224|Proteobacteria,1S41A@1236|Gammaproteobacteria,4674S@72275|Alteromonadaceae 1236|Gammaproteobacteria S Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant ectC - 4.2.1.108 ko:K06720 ko00260,ko01100,ko01120,map00260,map01100,map01120 M00033 R06979 RC01729 ko00000,ko00001,ko00002,ko01000 - - - Ectoine_synth k141_19430_1 218284.CCDN010000001_gene671 3.31e-120 353.0 COG0124@1|root,COG0124@2|Bacteria,1TP3D@1239|Firmicutes,4HAM2@91061|Bacilli,1ZBXR@1386|Bacillus 91061|Bacilli J histidyl-tRNA synthetase hisS - 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_2b,tRNA-synt_His k141_14633_1 218284.CCDN010000002_gene2817 2.67e-52 176.0 2CDJQ@1|root,2Z7JX@2|Bacteria,1TR73@1239|Firmicutes,4HAT1@91061|Bacilli,1ZRA6@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_14633_2 1169144.KB910950_gene3262 5.6e-12 65.9 COG1595@1|root,COG1595@2|Bacteria,1VEMV@1239|Firmicutes,4HP80@91061|Bacilli,1ZFIF@1386|Bacillus 91061|Bacilli K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_8796_1 1234664.AMRO01000003_gene705 2.56e-12 65.9 COG4412@1|root,COG4412@2|Bacteria,1TQYP@1239|Firmicutes,4HD82@91061|Bacilli,1WEZN@129337|Geobacillus 91061|Bacilli S Immune inhibitor A peptidase M6 - - - ko:K09607 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M6 k141_24145_1 1042377.AFPJ01000042_gene1015 4.43e-57 198.0 COG1472@1|root,COG1472@2|Bacteria,1MVAJ@1224|Proteobacteria,1RMQF@1236|Gammaproteobacteria,465G4@72275|Alteromonadaceae 1236|Gammaproteobacteria G Beta-N-acetylhexosaminidase ybbD - 3.2.1.52 ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 M00628 R00022,R05963,R07809,R07810,R10831 RC00049 ko00000,ko00001,ko00002,ko01000 - - - Glyco_hydro_3,Glyco_hydro_3_C k141_24145_2 1042377.AFPJ01000042_gene1014 5.32e-247 690.0 COG0154@1|root,COG0154@2|Bacteria,1MWWQ@1224|Proteobacteria,1RMKH@1236|Gammaproteobacteria,466AW@72275|Alteromonadaceae 1236|Gammaproteobacteria J Belongs to the amidase family nylA - 3.5.1.4,6.3.5.6,6.3.5.7 ko:K01426,ko:K02433 ko00330,ko00360,ko00380,ko00627,ko00643,ko00970,ko01100,ko01120,map00330,map00360,map00380,map00627,map00643,map00970,map01100,map01120 - R02540,R03096,R03180,R03905,R03909,R04212,R05551,R05590 RC00010,RC00100,RC00950,RC01025 ko00000,ko00001,ko01000,ko03029 - - - Amidase k141_24145_3 1042377.AFPJ01000042_gene1013 8.62e-117 342.0 COG4336@1|root,COG4336@2|Bacteria,1MW52@1224|Proteobacteria,1RN4P@1236|Gammaproteobacteria,463YD@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the D-glutamate cyclase family - - - - - - - - - - - - DUF1445 k141_24145_4 42565.FP66_15680 3.52e-45 158.0 COG2049@1|root,COG2049@2|Bacteria,1MWRB@1224|Proteobacteria,1RQIQ@1236|Gammaproteobacteria,1XJXV@135619|Oceanospirillales 135619|Oceanospirillales E Allophanate hydrolase subunit 1 - - - - - - - - - - - - CT_C_D k141_24145_5 443152.MDG893_03945 5.03e-73 234.0 COG1984@1|root,COG1984@2|Bacteria,1MU9H@1224|Proteobacteria,1RR39@1236|Gammaproteobacteria,466NG@72275|Alteromonadaceae 1236|Gammaproteobacteria E Allophanate hydrolase subunit 2 - - - - - - - - - - - - CT_A_B k141_30043_1 1255043.TVNIR_2243 5.19e-47 163.0 COG1262@1|root,COG1262@2|Bacteria,1MUNC@1224|Proteobacteria,1RQI4@1236|Gammaproteobacteria,1WVY9@135613|Chromatiales 135613|Chromatiales S DinB superfamily - - - - - - - - - - - - DinB_2,FGE-sulfatase k141_7513_1 1294265.JCM21738_2689 4.02e-13 67.8 COG0367@1|root,COG0367@2|Bacteria,1TRPB@1239|Firmicutes,4HA44@91061|Bacilli,1ZBY8@1386|Bacillus 91061|Bacilli E Asparagine synthase asnO - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 k141_7513_2 1294265.JCM21738_2688 4.33e-46 152.0 2E4ZB@1|root,32ZT1@2|Bacteria,1VHAC@1239|Firmicutes,4HQBP@91061|Bacilli,1ZD5D@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2777) yisN - - - - - - - - - - - DUF2777 k141_4068_1 406124.ACPC01000049_gene87 1.9e-95 293.0 28KUD@1|root,2ZAB6@2|Bacteria,1TRII@1239|Firmicutes,4HA8V@91061|Bacilli,1ZCE4@1386|Bacillus 91061|Bacilli S YndJ-like protein yndJ - - - - - - - - - - - YndJ k141_12466_1 987059.RBXJA2T_00759 6.89e-11 60.8 2E3B5@1|root,32YAP@2|Bacteria,1N7KQ@1224|Proteobacteria,2VWEG@28216|Betaproteobacteria 28216|Betaproteobacteria S Protein of unknown function (DUF2721) - - - - - - - - - - - - DUF2721 k141_12466_2 351348.Maqu_2917 6.57e-24 104.0 2EBDF@1|root,335E4@2|Bacteria,1NH7B@1224|Proteobacteria,1SHGY@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_559_1 218284.CCDN010000001_gene1896 7.51e-134 387.0 COG0743@1|root,COG0743@2|Bacteria,1TP1C@1239|Firmicutes,4HBAV@91061|Bacilli,1ZC3I@1386|Bacillus 91061|Bacilli I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) dxr GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05688 RC01452 ko00000,ko00001,ko00002,ko01000 - - - DXPR_C,DXP_redisom_C,DXP_reductoisom k141_25447_2 283942.IL1070 1.01e-13 72.0 28IBE@1|root,2Z8DX@2|Bacteria,1NC7D@1224|Proteobacteria,1RP6N@1236|Gammaproteobacteria,2QFS3@267893|Idiomarinaceae 1236|Gammaproteobacteria S Putative amidoligase enzyme - - - - - - - - - - - - Amidoligase_2 k141_27630_1 1116375.VEJY3_01800 5e-47 152.0 2AWNZ@1|root,31NJT@2|Bacteria,1QKAG@1224|Proteobacteria,1TIE0@1236|Gammaproteobacteria,1XYYG@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_27630_2 1116375.VEJY3_01785 1.11e-58 191.0 2DMB3@1|root,32FBS@2|Bacteria,1RM3S@1224|Proteobacteria,1S8Q4@1236|Gammaproteobacteria,1Y2AW@135623|Vibrionales 135623|Vibrionales M Domain of unknown function (DUF4382) - - - - - - - - - - - - DUF4382 k141_26784_1 1042377.AFPJ01000034_gene2384 9.48e-208 626.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,464Y3@72275|Alteromonadaceae 1236|Gammaproteobacteria T GGDEF domain - - - - - - - - - - - - EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9 k141_26784_3 1279017.AQYJ01000023_gene3126 2.54e-16 76.3 COG0565@1|root,COG0565@2|Bacteria,1N47Y@1224|Proteobacteria,1RPD3@1236|Gammaproteobacteria,465US@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA trmJ - 2.1.1.200 ko:K02533,ko:K15396 - - - - ko00000,ko01000,ko03016 - - - SpoU_methylase k141_12467_1 1116375.VEJY3_00175 5.67e-98 312.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1XSSQ@135623|Vibrionales 135623|Vibrionales V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K18138 ko01501,ko01503,map01501,map01503 M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2 - - ACR_tran k141_5209_1 1453501.JELR01000001_gene2021 1.55e-139 404.0 COG0520@1|root,COG0520@2|Bacteria,1PJFE@1224|Proteobacteria,1RRJK@1236|Gammaproteobacteria,465WY@72275|Alteromonadaceae 1236|Gammaproteobacteria E Selenocysteine lyase - - - - - - - - - - - - Aminotran_5 k141_5209_2 1121935.AQXX01000131_gene2844 9.02e-88 259.0 COG0346@1|root,COG0346@2|Bacteria,1RCYX@1224|Proteobacteria,1S1Z9@1236|Gammaproteobacteria,1XJS8@135619|Oceanospirillales 135619|Oceanospirillales E Glyoxalase bleomycin resistance protein dioxygenase - - 4.4.1.5 ko:K01759 ko00620,map00620 - R02530 RC00004,RC00740 ko00000,ko00001,ko01000 - - - Glyoxalase k141_10254_4 1279017.AQYJ01000021_gene2820 3.51e-191 546.0 COG4805@1|root,COG4805@2|Bacteria,1MZDR@1224|Proteobacteria,1RZK8@1236|Gammaproteobacteria,465YN@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein conserved in bacteria - - - - - - - - - - - - - k141_25695_1 1127673.GLIP_1844 5.26e-139 445.0 COG3866@1|root,COG4677@1|root,COG5276@1|root,COG3866@2|Bacteria,COG4677@2|Bacteria,COG5276@2|Bacteria,1QPFF@1224|Proteobacteria,1RY07@1236|Gammaproteobacteria,465CR@72275|Alteromonadaceae 1236|Gammaproteobacteria G Amb_all pelB - 4.2.2.2 ko:K01728 ko00040,ko02024,map00040,map02024 - R02361,R06240 RC00049,RC00705 ko00000,ko00001,ko01000 - - - Pec_lyase_C,Pectinesterase k141_12676_1 1294265.JCM21738_4844 3.54e-52 172.0 COG4853@1|root,COG4853@2|Bacteria,1V1FW@1239|Firmicutes,4HFWZ@91061|Bacilli,1ZDGV@1386|Bacillus 91061|Bacilli S protein conserved in bacteria yycI - - - - - - - - - - - YycI k141_5464_1 420246.GTNG_1828 2.06e-05 46.6 COG0160@1|root,COG0160@2|Bacteria,1VS6F@1239|Firmicutes,4H9M7@91061|Bacilli,1WES9@129337|Geobacillus 91061|Bacilli E Aminotransferase class-III gabT - 2.6.1.19 ko:K00823 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 M00027 R00908,R01648 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 k141_5464_2 1305836.AXVE01000011_gene838 8.92e-27 110.0 COG3314@1|root,COG3314@2|Bacteria,1TR35@1239|Firmicutes,4HAB6@91061|Bacilli,26EDM@186818|Planococcaceae 91061|Bacilli S Nucleoside recognition - - - - - - - - - - - - Gate k141_26997_1 1121024.AUCD01000001_gene1701 4.29e-49 168.0 COG0017@1|root,COG0017@2|Bacteria,1TP38@1239|Firmicutes,4H9YH@91061|Bacilli,27FBA@186828|Carnobacteriaceae 91061|Bacilli J tRNA synthetases class II (D, K and N) asnS GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.22 ko:K01893 ko00970,map00970 M00359,M00360 R03648 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2,tRNA_anti-codon k141_26997_2 1073999.BN137_95 2.01e-06 50.4 COG1694@1|root,COG3956@2|Bacteria,1MVKM@1224|Proteobacteria,1RNVU@1236|Gammaproteobacteria 1236|Gammaproteobacteria C nucleoside triphosphate pyrophosphohydrolase mazG GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009267,GO:0009394,GO:0009605,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042594,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.9 ko:K04765 ko00230,ko00240,ko00760,ko00770,ko01100,map00230,map00240,map00760,map00770,map01100 - R00086,R00087,R00103,R00287,R00426,R00515,R00662,R00720,R03004,R03036,R11323 RC00002 ko00000,ko00001,ko01000 - - iAF1260.b2781,iBWG_1329.BWG_2516,iE2348C_1286.E2348C_3048,iEC55989_1330.EC55989_3056,iECDH10B_1368.ECDH10B_2948,iECDH1ME8569_1439.ECDH1ME8569_2691,iECH74115_1262.ECH74115_4041,iECIAI1_1343.ECIAI1_2889,iECO103_1326.ECO103_3324,iECO111_1330.ECO111_3505,iECO26_1355.ECO26_3851,iECOK1_1307.ECOK1_3155,iECP_1309.ECP_2762,iECSE_1348.ECSE_3039,iECSP_1301.ECSP_3733,iECW_1372.ECW_m2990,iECs_1301.ECs3641,iEKO11_1354.EKO11_0987,iEcDH1_1363.EcDH1_0907,iEcE24377_1341.EcE24377A_3085,iEcHS_1320.EcHS_A2925,iEcolC_1368.EcolC_0931,iG2583_1286.G2583_3433,iJO1366.b2781,iJR904.b2781,iSBO_1134.SBO_2662,iSSON_1240.SSON_2938,iSbBS512_1146.SbBS512_E3092,iUMN146_1321.UM146_02665,iUMNK88_1353.UMNK88_3464,iUTI89_1310.UTI89_C3150,iWFL_1372.ECW_m2990,iY75_1357.Y75_RS14470,iZ_1308.Z4096 MazG k141_24336_1 1161401.ASJA01000013_gene767 2.8e-203 573.0 COG0701@1|root,COG0701@2|Bacteria,1NC9F@1224|Proteobacteria,2U1D0@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Predicted permease - - - ko:K07089 - - - - ko00000 - - - ArsP_1 k141_24336_2 1279017.AQYJ01000028_gene2347 2e-273 753.0 28I1X@1|root,2Z86C@2|Bacteria,1PPMS@1224|Proteobacteria,1RV76@1236|Gammaproteobacteria,465Y1@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_24336_3 1279017.AQYJ01000028_gene2346 1.12e-103 303.0 28H65@1|root,2Z7IN@2|Bacteria,1Q4IY@1224|Proteobacteria,1RZHE@1236|Gammaproteobacteria,46703@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - Phage_lambda_P k141_24336_5 207954.MED92_11069 3.26e-85 256.0 COG1418@1|root,COG1418@2|Bacteria,1RJ5U@1224|Proteobacteria,1SAZE@1236|Gammaproteobacteria,1XPKV@135619|Oceanospirillales 135619|Oceanospirillales S mRNA catabolic process - - - - - - - - - - - - - k141_24336_6 1042377.AFPJ01000004_gene407 2.51e-245 699.0 COG4247@1|root,COG4247@2|Bacteria,1MVTA@1224|Proteobacteria,1RQXH@1236|Gammaproteobacteria,46571@72275|Alteromonadaceae 1236|Gammaproteobacteria I Phytase phy - 3.1.3.8 ko:K01083 ko00562,map00562 - R03371 RC00078 ko00000,ko00001,ko01000 - - - Phytase k141_24336_7 1042377.AFPJ01000004_gene406 0.0 1202.0 COG1629@1|root,COG4771@2|Bacteria,1MUWN@1224|Proteobacteria,1RN1E@1236|Gammaproteobacteria,464FG@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec k141_24336_8 1453501.JELR01000005_gene1695 0.0 1021.0 COG3211@1|root,COG3211@2|Bacteria,1MU8T@1224|Proteobacteria,1RMIU@1236|Gammaproteobacteria,464FZ@72275|Alteromonadaceae 1236|Gammaproteobacteria S Bacterial protein of unknown function (DUF839) uxpB - - ko:K07093 - - - - ko00000 - - - DUF839 k141_24336_9 1279017.AQYJ01000028_gene2337 5.71e-115 332.0 COG2095@1|root,COG2095@2|Bacteria,1MX5T@1224|Proteobacteria,1RPZ3@1236|Gammaproteobacteria,466UP@72275|Alteromonadaceae 1236|Gammaproteobacteria U UPF0056 membrane protein - - - ko:K05595 - - - - ko00000,ko02000 2.A.95.1 - - MarC k141_11449_1 1279017.AQYJ01000028_gene2137 2.02e-189 550.0 COG0308@1|root,COG0308@2|Bacteria,1PJTM@1224|Proteobacteria,1SYS3@1236|Gammaproteobacteria,4672R@72275|Alteromonadaceae 1236|Gammaproteobacteria E Peptidase family M1 domain - - 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - ERAP1_C,Peptidase_M1 k141_19688_1 218284.CCDN010000007_gene3792 2.77e-127 372.0 COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,4H9MW@91061|Bacilli,1ZBKI@1386|Bacillus 91061|Bacilli L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids dnaA GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - ko:K02313 ko02020,ko04112,map02020,map04112 - - - ko00000,ko00001,ko03032,ko03036 - - - Bac_DnaA,Bac_DnaA_C,DnaA_N k141_757_1 543632.JOJL01000017_gene9932 7.73e-42 142.0 COG3832@1|root,COG3832@2|Bacteria,2IN0A@201174|Actinobacteria 201174|Actinobacteria S Polyketide cyclase / dehydrase and lipid transport - - - - - - - - - - - - Polyketide_cyc2 k141_757_2 1385510.N781_08965 5.11e-46 157.0 COG0640@1|root,COG0640@2|Bacteria,1VJ43@1239|Firmicutes,4HQM5@91061|Bacilli,2YAHB@289201|Pontibacillus 91061|Bacilli K Activator of Hsp90 ATPase homolog 1-like protein - - - - - - - - - - - - AHSA1,HTH_20 k141_33926_1 1347086.CCBA010000017_gene351 1.33e-85 259.0 29A5D@1|root,31HSA@2|Bacteria,1UABN@1239|Firmicutes,4IKPT@91061|Bacilli,1ZMUV@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2711) - - - - - - - - - - - - DUF2711 k141_13885_2 218284.CCDN010000005_gene3427 5.16e-35 123.0 COG1051@1|root,COG1051@2|Bacteria,1V4TX@1239|Firmicutes,4HH70@91061|Bacilli,1ZGXJ@1386|Bacillus 91061|Bacilli F Belongs to the Nudix hydrolase family - - - - - - - - - - - - NUDIX k141_25708_2 218284.CCDN010000001_gene936 9.08e-29 108.0 COG0703@1|root,COG0703@2|Bacteria,1VA6Z@1239|Firmicutes,4HKD6@91061|Bacilli,1ZHX4@1386|Bacillus 91061|Bacilli F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate aroK GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - SKI k141_1727_1 1294265.JCM21738_1435 6.32e-96 298.0 COG2199@1|root,COG5001@1|root,COG3706@2|Bacteria,COG5001@2|Bacteria,1UI7N@1239|Firmicutes,4ISN0@91061|Bacilli,1ZS9J@1386|Bacillus 91061|Bacilli T diguanylate cyclase - - - - - - - - - - - - GGDEF,MHYT,PAS,PAS_4,PAS_9 k141_18558_1 1042377.AFPJ01000037_gene2979 5.72e-109 317.0 COG0655@1|root,COG0655@2|Bacteria,1MW7N@1224|Proteobacteria,1S23B@1236|Gammaproteobacteria,466IM@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the WrbA family wrbA - 1.6.5.2 ko:K03809 ko00130,ko01110,map00130,map01110 - R02964,R03643,R03816 RC00819 ko00000,ko00001,ko01000 - - - FMN_red k141_32566_1 1090320.KB900605_gene3031 5.3e-14 75.9 COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2TT4A@28211|Alphaproteobacteria,2K7F9@204457|Sphingomonadales 204457|Sphingomonadales C CoA-transferase family III - - - - - - - - - - - - CoA_transf_3 k141_32566_2 1042377.AFPJ01000021_gene2117 3.9e-100 310.0 COG2244@1|root,COG2244@2|Bacteria 2|Bacteria S polysaccharide biosynthetic process - - - - - - - - - - - - MatE,Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C k141_2929_1 218284.CCDN010000001_gene1345 2.99e-79 239.0 COG4915@1|root,COG4915@2|Bacteria,1V5B1@1239|Firmicutes,4HKAX@91061|Bacilli,1ZG4A@1386|Bacillus 91061|Bacilli S 5-bromo-4-chloroindolyl phosphate hydrolysis protein xpaC - - - - - - - - - - - Halogen_Hydrol k141_13886_1 218284.CCDN010000001_gene1313 1.76e-69 214.0 COG1309@1|root,COG1309@2|Bacteria,1VFD2@1239|Firmicutes,4HM3Q@91061|Bacilli,1ZIA5@1386|Bacillus 91061|Bacilli K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N k141_11450_1 218284.CCDN010000002_gene2101 6.52e-137 395.0 COG2984@1|root,COG2984@2|Bacteria,1TPB0@1239|Firmicutes,4HESK@91061|Bacilli,1ZBBC@1386|Bacillus 91061|Bacilli S transport system, periplasmic component - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind k141_24358_2 218284.CCDN010000001_gene747 2.99e-102 306.0 COG0561@1|root,COG0561@2|Bacteria,1TR3N@1239|Firmicutes,4HC8P@91061|Bacilli,1ZBP7@1386|Bacillus 91061|Bacilli S Stage IV sporulation yqfD - - ko:K06438 - - - - ko00000 - - - YqfD k141_7670_1 218284.CCDN010000006_gene3745 1.48e-128 385.0 COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,4HAAG@91061|Bacilli,1ZPV2@1386|Bacillus 91061|Bacilli G Belongs to the glycosyl hydrolase 3 family bglX - 3.2.1.21,3.2.1.52 ko:K01207,ko:K05349 ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501 M00628 R00022,R00026,R02558,R02887,R02985,R03527,R04949,R04998,R05963,R07809,R07810,R10035,R10039,R10040,R10831 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko00002,ko01000 - GH3 - Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C k141_4218_1 1279017.AQYJ01000026_gene58 3.67e-116 377.0 COG1361@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4932@2|Bacteria,1R5G4@1224|Proteobacteria,1SEWA@1236|Gammaproteobacteria,469S7@72275|Alteromonadaceae 1236|Gammaproteobacteria M Domain of unknown function DUF11 - - - - - - - - - - - - DUF11,SdrD_B k141_30180_2 218284.CCDN010000007_gene3973 2.92e-159 455.0 COG1158@1|root,COG1158@2|Bacteria,1TPHZ@1239|Firmicutes,4H9XB@91061|Bacilli,1ZBN9@1386|Bacillus 91061|Bacilli K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template rho - - ko:K03628 ko03018,map03018 - - - ko00000,ko00001,ko03019,ko03021 - - - ATP-synt_ab,Rho_N,Rho_RNA_bind k141_11451_1 218284.CCDN010000005_gene3458 5.22e-92 272.0 COG2032@1|root,COG2032@2|Bacteria,1V652@1239|Firmicutes,4HH67@91061|Bacilli,1ZE46@1386|Bacillus 91061|Bacilli P Destroys radicals which are normally produced within the cells and which are toxic to biological systems sodC GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0005488,GO:0005507,GO:0005515,GO:0005575,GO:0005576,GO:0005615,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008270,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044237,GO:0044421,GO:0046872,GO:0046914,GO:0046983,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1 ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 - - - ko00000,ko00001,ko01000 - - - Sod_Cu k141_19690_1 1294265.JCM21738_2996 2.46e-122 356.0 COG2141@1|root,COG2141@2|Bacteria,1TQWJ@1239|Firmicutes,4HBMR@91061|Bacilli,1ZAPR@1386|Bacillus 91061|Bacilli C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases yvbT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - - - - - - - - - - Bac_luciferase k141_19690_2 1307436.PBF_14159 3.64e-15 74.7 COG5146@1|root,COG5146@2|Bacteria,1V2R2@1239|Firmicutes,4HG04@91061|Bacilli,1ZEC9@1386|Bacillus 91061|Bacilli H Pantothenate kinase coaW - 2.7.1.33 ko:K09680 ko00770,ko01100,map00770,map01100 M00120 R02971,R03018,R04391 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Fumble k141_5484_1 218284.CCDN010000001_gene1090 1.48e-41 142.0 COG5581@1|root,COG5581@2|Bacteria,1V31U@1239|Firmicutes,4HGFE@91061|Bacilli,1ZCCG@1386|Bacillus 91061|Bacilli M Flagellar protein YcgR ypfA - - - - - - - - - - - PilZ,YcgR_2 k141_18560_1 935836.JAEL01000134_gene1815 8.22e-91 273.0 COG0179@1|root,COG0179@2|Bacteria,1TQDQ@1239|Firmicutes,4HCBR@91061|Bacilli,1ZCHF@1386|Bacillus 91061|Bacilli Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) yisK - - - - - - - - - - - FAA_hydrolase k141_2930_2 218284.CCDN010000003_gene2993 8.95e-48 154.0 COG1188@1|root,COG1188@2|Bacteria,1VEI5@1239|Firmicutes,4HKJJ@91061|Bacilli,1ZHXN@1386|Bacillus 91061|Bacilli J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) yabO - - - - - - - - - - - S4 k141_10268_1 1116375.VEJY3_13920 0.0 2006.0 COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,1RMYD@1236|Gammaproteobacteria,1XSUY@135623|Vibrionales 135623|Vibrionales E COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain metH GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 ko:K00548 ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230 M00017 R00946,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans k141_10268_2 1116375.VEJY3_13915 1.54e-305 835.0 COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,1RMJ6@1236|Gammaproteobacteria,1XSHB@135623|Vibrionales 135623|Vibrionales E Belongs to the aspartokinase family lysC - 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase k141_10268_3 1116375.VEJY3_13910 4.91e-263 721.0 COG0075@1|root,COG0075@2|Bacteria,1MWHJ@1224|Proteobacteria,1RMNR@1236|Gammaproteobacteria,1XSCB@135623|Vibrionales 135623|Vibrionales E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase - - 2.6.1.44,2.6.1.45,2.6.1.51 ko:K00830 ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 M00346,M00532 R00369,R00372,R00585,R00588 RC00006,RC00008,RC00018 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_5 k141_10268_4 1116375.VEJY3_13905 7.85e-135 397.0 COG3307@1|root,COG3307@2|Bacteria,1N5VZ@1224|Proteobacteria,1RMC4@1236|Gammaproteobacteria,1XUTS@135623|Vibrionales 135623|Vibrionales M COG3307 Lipid A core - O-antigen ligase and related enzymes - - - ko:K13009 - - - - ko00000,ko01000,ko01005 - - - PglL_A,Wzy_C,Wzy_C_2 k141_12687_1 1116375.VEJY3_22381 1.72e-248 694.0 COG1807@1|root,COG1807@2|Bacteria,1NMIZ@1224|Proteobacteria,1RMA2@1236|Gammaproteobacteria,1XUWV@135623|Vibrionales 135623|Vibrionales M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - - - - - - - - - - PMT k141_12687_2 558884.JRGM01000176_gene1406 6.06e-81 248.0 COG0834@1|root,COG0834@2|Bacteria,1NT2J@1224|Proteobacteria,1S077@1236|Gammaproteobacteria,1Y541@135624|Aeromonadales 135624|Aeromonadales ET Belongs to the bacterial solute-binding protein 3 family - - - ko:K10022 ko02010,map02010 M00235 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.11 - - SBP_bac_3 k141_23302_1 218284.CCDN010000001_gene1158 1.98e-111 342.0 COG1205@1|root,COG1205@2|Bacteria,1TSPA@1239|Firmicutes,4H9T2@91061|Bacilli,1ZDM5@1386|Bacillus 91061|Bacilli L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster yprA GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - ko:K06877 - - - - ko00000 - - - DEAD,DUF1998,Helicase_C k141_24360_1 1294265.JCM21738_3957 3.1e-112 330.0 COG1466@1|root,COG1466@2|Bacteria,1TRM0@1239|Firmicutes,4HBB4@91061|Bacilli,1ZBST@1386|Bacillus 91061|Bacilli L DNA polymerase III delta subunit holA - 2.7.7.7 ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta k141_4219_1 1042377.AFPJ01000019_gene2519 6.53e-70 223.0 COG0438@1|root,COG0438@2|Bacteria,1MUTA@1224|Proteobacteria,1RS31@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Glycosyl transferase - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 k141_19691_1 218284.CCDN010000001_gene1963 6.05e-132 381.0 COG1600@1|root,COG1600@2|Bacteria,1TP6Q@1239|Firmicutes,4HAEW@91061|Bacilli,1ZC1W@1386|Bacillus 91061|Bacilli C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) queG GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 ko:K18979 - - - - ko00000,ko01000,ko03016 - - - DUF1730,Fer4_16,HEAT_2 k141_16050_1 223926.28809782 5.1e-59 183.0 COG3097@1|root,COG3097@2|Bacteria,1NBAT@1224|Proteobacteria,1SAZG@1236|Gammaproteobacteria,1XXWY@135623|Vibrionales 135623|Vibrionales S Belongs to the UPF0267 family - - - ko:K09900 - - - - ko00000 - - - ASCH k141_16050_2 1280001.BAOA01000026_gene5120 3.45e-196 546.0 COG2084@1|root,COG2084@2|Bacteria,1MUGU@1224|Proteobacteria,1RQ2D@1236|Gammaproteobacteria,1XUTE@135623|Vibrionales 135623|Vibrionales I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases - - 1.1.1.31 ko:K00020 ko00280,ko01100,map00280,map01100 - R05066 RC00099 ko00000,ko00001,ko01000 - - - NAD_binding_11,NAD_binding_2 k141_16050_3 1116375.VEJY3_23186 5.09e-142 402.0 COG0637@1|root,COG0637@2|Bacteria,1R8Z3@1224|Proteobacteria,1S4ZI@1236|Gammaproteobacteria,1XT2Y@135623|Vibrionales 135623|Vibrionales S phosphatase phosphohexomutase - - - - - - - - - - - - HAD_2 k141_16050_4 1116375.VEJY3_23191 6.4e-89 262.0 COG3241@1|root,COG3241@2|Bacteria,1RHV2@1224|Proteobacteria,1S6H8@1236|Gammaproteobacteria,1XWZG@135623|Vibrionales 135623|Vibrionales C Transfers electrons from cytochrome c551 to cytochrome oxidase azu - - - - - - - - - - - Copper-bind k141_16050_5 1116375.VEJY3_23231 0.0 1112.0 COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria,1XSH6@135623|Vibrionales 135623|Vibrionales V COG1132 ABC-type multidrug transport system, ATPase and permease components - - - ko:K06147,ko:K18893 ko02010,map02010 - - - ko00000,ko00001,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran k141_16050_6 1116375.VEJY3_23236 0.0 943.0 COG4773@1|root,COG4773@2|Bacteria,1QTT0@1224|Proteobacteria,1RNBT@1236|Gammaproteobacteria,1XT1K@135623|Vibrionales 135623|Vibrionales P COG1629 Outer membrane receptor proteins, mostly Fe transport fhuA - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_16050_7 1116375.VEJY3_23241 4.2e-169 474.0 COG1120@1|root,COG1120@2|Bacteria,1MUNG@1224|Proteobacteria,1RQ6C@1236|Gammaproteobacteria,1XV8S@135623|Vibrionales 135623|Vibrionales HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components fhuB - 3.6.3.34 ko:K02013 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 - - ABC_tran k141_16050_8 1116375.VEJY3_23246 3.94e-175 493.0 COG0614@1|root,COG0614@2|Bacteria,1PEJ1@1224|Proteobacteria,1RNIS@1236|Gammaproteobacteria,1XWC1@135623|Vibrionales 135623|Vibrionales P ABC-type Fe3 -hydroxamate transport system, periplasmic component VPA1437 - - ko:K02016 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - Peripla_BP_2 k141_16050_9 1116375.VEJY3_23251 7.66e-242 681.0 COG0609@1|root,COG0609@2|Bacteria,1MVA3@1224|Proteobacteria,1RN0J@1236|Gammaproteobacteria,1XT0D@135623|Vibrionales 135623|Vibrionales P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily - - - ko:K02015 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - FecCD k141_30181_1 218284.CCDN010000005_gene3352 5.67e-64 207.0 2BCUG@1|root,326F1@2|Bacteria,1V8P9@1239|Firmicutes,4HYG5@91061|Bacilli,1ZHBA@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_17217_1 218284.CCDN010000001_gene1597 5.11e-95 287.0 COG1916@1|root,COG1916@2|Bacteria,1TSWJ@1239|Firmicutes,4HANT@91061|Bacilli,1ZC3N@1386|Bacillus 91061|Bacilli S TraB family traB - - - - - - - - - - - TraB k141_32569_1 218284.CCDN010000002_gene2849 1.49e-127 369.0 COG0697@1|root,COG0697@2|Bacteria,1TRKE@1239|Firmicutes,4HF69@91061|Bacilli,1ZQ3B@1386|Bacillus 91061|Bacilli EG EamA-like transporter family - - - - - - - - - - - - EamA k141_25710_2 118166.JH976537_gene2134 5.23e-38 134.0 COG3453@1|root,COG3453@2|Bacteria,1G6UU@1117|Cyanobacteria,1HBYN@1150|Oscillatoriales 1117|Cyanobacteria S Putative phosphatase (DUF442) - - - - - - - - - - - - DUF442 k141_11453_1 218284.CCDN010000007_gene3814 1.49e-160 465.0 COG3887@1|root,COG3887@2|Bacteria,1TPGP@1239|Firmicutes,4HBVH@91061|Bacilli,1ZCB0@1386|Bacillus 91061|Bacilli T signaling protein consisting of a modified GGDEF domain and a DHH domain yybT - - - - - - - - - - - DHH,DHHA1 k141_10270_1 1177154.Y5S_02286 1.68e-08 59.7 COG0823@1|root,COG0823@2|Bacteria,1R3VN@1224|Proteobacteria,1RNKG@1236|Gammaproteobacteria,1XNC8@135619|Oceanospirillales 135619|Oceanospirillales U COG0823 Periplasmic component of the Tol biopolymer transport system - - - - - - - - - - - - PD40 k141_4220_1 1294265.JCM21738_2375 1.25e-101 309.0 28HMX@1|root,2Z7WB@2|Bacteria,1TPJG@1239|Firmicutes,4HBRI@91061|Bacilli,1ZCDH@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_1731_1 1196031.ALEG01000011_gene5217 1.71e-61 197.0 COG0726@1|root,COG0726@2|Bacteria,1TPWK@1239|Firmicutes,4HEQ2@91061|Bacilli,1ZPWD@1386|Bacillus 91061|Bacilli G Polysaccharide deacetylase - - - - - - - - - - - - Polysacc_deac_1 k141_13891_1 720555.BATR1942_12885 5e-90 277.0 COG2124@1|root,COG2124@2|Bacteria,1TPWZ@1239|Firmicutes,4HAGS@91061|Bacilli,1ZC1Y@1386|Bacillus 91061|Bacilli C Cytochrome P450 bioI GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.14.14.46 ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 M00573 R10123 - ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 - - - p450 k141_18562_1 1352230.S6BFI4_9CAUD 2.21e-20 92.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales 28883|Caudovirales S N-acetylmuramoyl-L-alanine amidase activity - - - - - - - - - - - - - k141_23304_1 218284.CCDN010000005_gene3416 1.28e-137 396.0 COG1052@1|root,COG1052@2|Bacteria,1TPCX@1239|Firmicutes,4HASY@91061|Bacilli,1ZB0I@1386|Bacillus 91061|Bacilli CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family gyaR - 1.1.1.26 ko:K00015 ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120 - R00717,R01388 RC00031,RC00042 ko00000,ko00001,ko01000 - - - 2-Hacid_dh,2-Hacid_dh_C k141_22003_1 1219077.VAZ01S_004_00270 3.46e-218 604.0 COG2113@1|root,COG2113@2|Bacteria,1MVXS@1224|Proteobacteria,1RQ3U@1236|Gammaproteobacteria,1XTHK@135623|Vibrionales 135623|Vibrionales E COG2113 ABC-type proline glycine betaine transport systems, periplasmic components opuAC - - ko:K02002 ko02010,map02010 M00208 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - OpuAC k141_22003_2 1280001.BAOA01000045_gene1710 1.63e-185 519.0 COG4176@1|root,COG4176@2|Bacteria,1MUM4@1224|Proteobacteria,1RPQS@1236|Gammaproteobacteria,1XTMM@135623|Vibrionales 135623|Vibrionales P COG4176 ABC-type proline glycine betaine transport system, permease component opuAB - - ko:K02001 ko02010,map02010 M00208 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - BPD_transp_1 k141_22003_3 1219077.VAZ01S_004_00250 1.18e-232 648.0 COG4175@1|root,COG4175@2|Bacteria,1MU86@1224|Proteobacteria,1RN2R@1236|Gammaproteobacteria,1XTVT@135623|Vibrionales 135623|Vibrionales E COG4175 ABC-type proline glycine betaine transport system, ATPase component proV - 3.6.3.32 ko:K02000 ko02010,map02010 M00208 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.12 - - ABC_tran,CBS k141_22003_4 1201293.AKXQ01000004_gene2258 1.19e-215 618.0 COG0515@1|root,COG0631@1|root,COG0515@2|Bacteria,COG0631@2|Bacteria,1MV1P@1224|Proteobacteria,1RNQN@1236|Gammaproteobacteria 1236|Gammaproteobacteria KLT Serine Threonine protein - - 3.1.3.16 ko:K01090,ko:K20074 - - - - ko00000,ko01000,ko01009 - - - PP2C_2,Pkinase k141_24362_1 136993.KB900626_gene1422 7.23e-44 154.0 COG1043@1|root,COG1043@2|Bacteria,1MUHQ@1224|Proteobacteria,2TRK9@28211|Alphaproteobacteria,36XIF@31993|Methylocystaceae 28211|Alphaproteobacteria M Udp N-acetylglucosamine O-acyltransferase; Domain 2 lpxA - 2.3.1.129 ko:K00677 ko00540,ko01100,ko01503,map00540,map01100,map01503 M00060 R04567 RC00039,RC00055 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Acetyltransf_11,Hexapep k141_24392_2 1325130.HFN_0748 9.05e-34 121.0 COG0756@1|root,COG0756@2|Bacteria,1RA7P@1224|Proteobacteria,42SJS@68525|delta/epsilon subdivisions,2YRU7@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA dut - 3.6.1.23 ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00053 R02100,R11896 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 - - iIT341.HP0865 dUTPase k141_5505_1 1279017.AQYJ01000025_gene760 5.09e-104 309.0 COG2304@1|root,COG2304@2|Bacteria,1MXQ7@1224|Proteobacteria,1RMDX@1236|Gammaproteobacteria,464NT@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein containing a von Willebrand factor type A (vWA) domain - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - VWA k141_16065_1 218284.CCDN010000006_gene3647 2.36e-101 301.0 COG0370@1|root,COG0370@2|Bacteria,1TQT3@1239|Firmicutes,4HAIZ@91061|Bacilli,1ZAYP@1386|Bacillus 91061|Bacilli P COG0370 Fe2 transport system protein B yvoD - - - - - - - - - - - Gate k141_13913_1 459349.CLOAM0906 3.24e-05 45.1 COG0621@1|root,COG0621@2|Bacteria,2NNUN@2323|unclassified Bacteria 2|Bacteria J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine miaB GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035597,GO:0035600,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360 2.8.4.3 ko:K06168 - - R10645,R10646,R10647 RC00003,RC00980,RC03221,RC03222 ko00000,ko01000,ko03016 - - - Radical_SAM,TRAM,UPF0004 k141_13913_2 1276920.ADIAG_00120 8.68e-09 60.5 COG0476@1|root,COG0476@2|Bacteria,2GJB6@201174|Actinobacteria,1W898@1268|Micrococcaceae 201174|Actinobacteria H The proteins in this cluster have high sequence similarity to MoeB and are possibly involved in the synthesis of molybdopterin, but there has been no biochemical or physiological characterization. There is also no genetic linkage to other molybdopterin cofactor synthesis proteins. These proteins are moeB GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006732,GO:0006777,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008146,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016782,GO:0018130,GO:0019344,GO:0019538,GO:0019637,GO:0019720,GO:0019752,GO:0020012,GO:0030312,GO:0030682,GO:0042783,GO:0043170,GO:0043207,GO:0043436,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0061605,GO:0070566,GO:0071704,GO:0071944,GO:0075136,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.80,2.8.1.11 ko:K21147 ko04122,map04122 - R07459,R07461 RC00043 ko00000,ko00001,ko01000 - - - Rhodanese,ThiF k141_14826_1 1294265.JCM21738_2091 2.57e-73 222.0 2ERU6@1|root,33JDD@2|Bacteria,1VQQZ@1239|Firmicutes,4HSUQ@91061|Bacilli,1ZFSV@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_31395_1 1145276.T479_07870 7.45e-21 89.4 COG1131@1|root,COG1131@2|Bacteria,1TQHS@1239|Firmicutes,4HC34@91061|Bacilli,3IZKI@400634|Lysinibacillus 91061|Bacilli V ATPases associated with a variety of cellular activities - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 k141_31395_2 218284.CCDN010000001_gene1689 1.32e-61 196.0 COG1277@1|root,COG1277@2|Bacteria,1TRD6@1239|Firmicutes,4HGGV@91061|Bacilli,1ZC8J@1386|Bacillus 91061|Bacilli S ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_2 k141_9013_1 218284.CCDN010000003_gene2999 1.27e-95 301.0 COG2208@1|root,COG2208@2|Bacteria,1TQ92@1239|Firmicutes,4HB0X@91061|Bacilli,1ZAYZ@1386|Bacillus 91061|Bacilli KT stage II sporulation protein E spoIIE GO:0005575,GO:0005623,GO:0042601,GO:0042763,GO:0044464 3.1.3.16 ko:K06382 - - - - ko00000,ko01000 - - - SpoIIE k141_7693_1 218284.CCDN010000007_gene3829 1.21e-104 306.0 COG1235@1|root,COG1235@2|Bacteria,1TQ8E@1239|Firmicutes,4HAKD@91061|Bacilli,1ZASY@1386|Bacillus 91061|Bacilli S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I vicX - 3.1.26.11 ko:K00784 ko03013,map03013 - - - ko00000,ko00001,ko01000,ko03016 - - - Lactamase_B,Lactamase_B_2 k141_23337_1 1144275.COCOR_05913 1.32e-81 262.0 COG0457@1|root,COG0457@2|Bacteria,1N0A9@1224|Proteobacteria,42YQ0@68525|delta/epsilon subdivisions,2WTRV@28221|Deltaproteobacteria,2YUFX@29|Myxococcales 28221|Deltaproteobacteria S COG0457 FOG TPR repeat - - - - - - - - - - - - - k141_30199_1 674977.VMC_00670 7.11e-211 592.0 COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,1RNV5@1236|Gammaproteobacteria,1XU22@135623|Vibrionales 135623|Vibrionales I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) - - 6.4.1.4 ko:K01969 ko00280,ko01100,map00280,map01100 M00036 R04138 RC00367,RC00942 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans k141_16179_2 666686.B1NLA3E_02720 9.55e-76 232.0 COG1268@1|root,COG1268@2|Bacteria,1TS7R@1239|Firmicutes,4I3QE@91061|Bacilli,1ZFZE@1386|Bacillus 91061|Bacilli S BioY family - - - ko:K03523 ko02010,map02010 M00581,M00582 - - ko00000,ko00001,ko00002,ko02000 2.A.88.1,2.A.88.2 - - BioY k141_25862_1 399739.Pmen_4556 2.53e-135 413.0 COG4773@1|root,COG4773@2|Bacteria,1MW5E@1224|Proteobacteria,1RMBD@1236|Gammaproteobacteria 1236|Gammaproteobacteria P receptor fhuE - - ko:K16088 - - - - ko00000,ko02000 1.B.14.1.10,1.B.14.1.3,1.B.14.1.8 - - Plug,TonB_dep_Rec k141_25862_2 1042377.AFPJ01000034_gene2413 9.19e-21 85.1 COG2841@1|root,COG2841@2|Bacteria,1NGDM@1224|Proteobacteria,1TB3I@1236|Gammaproteobacteria,46BU7@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF465) - - - ko:K09794 - - - - ko00000 - - - DUF465 k141_25862_3 323850.Shew_0859 4.39e-35 129.0 COG0625@1|root,COG0625@2|Bacteria,1RHSK@1224|Proteobacteria,1RR26@1236|Gammaproteobacteria,2QB9R@267890|Shewanellaceae 1236|Gammaproteobacteria O Glutathione S-transferase yibF GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C,GST_C_2,GST_N_3 k141_29245_3 1499680.CCFE01000021_gene1865 0.000272 43.1 COG0328@1|root,COG0328@2|Bacteria,1V3K2@1239|Firmicutes,4HE8H@91061|Bacilli,1ZDMZ@1386|Bacillus 91061|Bacilli L COG0328 Ribonuclease HI ypeP - 3.1.26.4 ko:K03469 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RVT_3 k141_37472_1 1178540.BA70_11160 2.22e-123 375.0 COG1887@1|root,COG1887@2|Bacteria,1TRU6@1239|Firmicutes,4HF9K@91061|Bacilli,1ZD17@1386|Bacillus 91061|Bacilli M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase - - - - - - - - - - - - Glyphos_transf k141_20868_1 1499680.CCFE01000011_gene574 5.84e-46 167.0 COG0737@1|root,COG2374@1|root,COG4085@1|root,COG5263@1|root,COG0737@2|Bacteria,COG2374@2|Bacteria,COG4085@2|Bacteria,COG5263@2|Bacteria,1TPV2@1239|Firmicutes,4HB9S@91061|Bacilli,1ZAY0@1386|Bacillus 91061|Bacilli F Belongs to the 5'-nucleotidase family yfkN - 3.1.3.5,3.1.3.6,3.1.4.16 ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01562,R01569,R01664,R01877,R01968,R02088,R02102,R02148,R02370,R02719,R03537,R03538,R03929,R05135 RC00017,RC00078,RC00296 ko00000,ko00001,ko01000 - - iYO844.BSU07840 5_nucleotid_C,Metallophos k141_36249_1 1279017.AQYJ01000028_gene2297 2.11e-71 238.0 COG2909@1|root,COG2909@2|Bacteria,1MVZZ@1224|Proteobacteria,1RN29@1236|Gammaproteobacteria,46AB4@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG2909 ATP-dependent transcriptional regulator malT GO:0003674,GO:0003700,GO:0005488,GO:0005515,GO:0005975,GO:0006355,GO:0008150,GO:0008152,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030246,GO:0031323,GO:0031326,GO:0042802,GO:0044238,GO:0048031,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070492,GO:0071704,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 - ko:K03556 - - - - ko00000,ko03000 - - - AAA_16,GerE k141_23484_1 1348114.OM33_02055 2.24e-71 241.0 COG1629@1|root,COG4206@1|root,COG4206@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria,2PZDP@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec k141_11597_1 1499685.CCFJ01000056_gene264 9.23e-14 71.6 COG0044@1|root,COG0044@2|Bacteria,1TPQM@1239|Firmicutes,4HA90@91061|Bacilli,1ZAS7@1386|Bacillus 91061|Bacilli F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily pyrC GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 k141_11597_2 218284.CCDN010000001_gene61 6.33e-71 221.0 COG0540@1|root,COG0540@2|Bacteria,1TQ96@1239|Firmicutes,4H9M6@91061|Bacilli,1ZBHG@1386|Bacillus 91061|Bacilli F Belongs to the ATCase OTCase family pyrB GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU15490 OTCace,OTCace_N k141_14108_1 218284.CCDN010000001_gene748 5.52e-81 247.0 COG1702@1|root,COG1702@2|Bacteria,1TP35@1239|Firmicutes,4HBD5@91061|Bacilli,1ZBVE@1386|Bacillus 91061|Bacilli T Phosphate starvation-inducible protein PhoH phoH - - ko:K06217 - - - - ko00000 - - - PhoH k141_23513_1 1279017.AQYJ01000022_gene2603 2.06e-151 441.0 COG0584@1|root,COG0584@2|Bacteria,1MVWZ@1224|Proteobacteria,1RRBP@1236|Gammaproteobacteria,464IE@72275|Alteromonadaceae 1236|Gammaproteobacteria C Glycerophosphoryl diester phosphodiesterase family glpQ GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0008081,GO:0008889,GO:0009279,GO:0016020,GO:0016787,GO:0016788,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0042578,GO:0042597,GO:0043167,GO:0043169,GO:0044462,GO:0044464,GO:0046872,GO:0071944 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - iECNA114_1301.ECNA114_2331,iECSF_1327.ECSF_2119 GDPD k141_23513_2 1120970.AUBZ01000023_gene2853 5.99e-40 137.0 COG4828@1|root,COG4828@2|Bacteria,1N984@1224|Proteobacteria,1TFHC@1236|Gammaproteobacteria,46C6Y@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF1622) - - - - - - - - - - - - DUF1622 k141_23513_3 62928.azo2604 1.1e-93 286.0 COG0697@1|root,COG0697@2|Bacteria,1MXJ6@1224|Proteobacteria,2VIA7@28216|Betaproteobacteria,2KWE2@206389|Rhodocyclales 206389|Rhodocyclales EG EamA-like transporter family - - - - - - - - - - - - EamA k141_23513_4 945550.VISI1226_12866 6.61e-50 160.0 COG0393@1|root,COG0393@2|Bacteria,1N0XM@1224|Proteobacteria,1S62I@1236|Gammaproteobacteria,1XXXM@135623|Vibrionales 135623|Vibrionales S Belongs to the UPF0145 family - - - - - - - - - - - - YbjQ_1 k141_23513_5 13690.CP98_05193 3.19e-18 79.0 COG3809@1|root,COG3809@2|Bacteria,1N6ZY@1224|Proteobacteria,2UFVY@28211|Alphaproteobacteria,2K6YY@204457|Sphingomonadales 204457|Sphingomonadales S Transcription factor zinc-finger - - - ko:K09981 - - - - ko00000 - - - zf-TFIIB k141_27194_1 218284.CCDN010000001_gene128 0.0 940.0 COG0843@1|root,COG0843@2|Bacteria,1TP2U@1239|Firmicutes,4HA4X@91061|Bacilli,1ZBD5@1386|Bacillus 91061|Bacilli C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B ctaD GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009486,GO:0009987,GO:0015002,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0034220,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.9.3.1 ko:K02274 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6 - - COX1 k141_10396_1 1122180.Lokhon_03053 6.16e-49 159.0 COG1006@1|root,COG1006@2|Bacteria,1RH8H@1224|Proteobacteria,2UA52@28211|Alphaproteobacteria,2P91H@245186|Loktanella 28211|Alphaproteobacteria P NADH-ubiquinone/plastoquinone oxidoreductase chain 4L phaC - - ko:K05560 - - - - ko00000,ko02000 2.A.63.1 - - Oxidored_q2 k141_31452_1 1279017.AQYJ01000026_gene314 1.05e-106 314.0 COG0697@1|root,COG0697@2|Bacteria,1N024@1224|Proteobacteria,1S1KP@1236|Gammaproteobacteria,46DI4@72275|Alteromonadaceae 1236|Gammaproteobacteria EG EamA-like transporter family - - - - - - - - - - - - EamA k141_30306_1 1042377.AFPJ01000028_gene2164 2.93e-62 197.0 COG0457@1|root,COG0457@2|Bacteria,1NB8N@1224|Proteobacteria,1SEZN@1236|Gammaproteobacteria,4683W@72275|Alteromonadaceae 1236|Gammaproteobacteria S TPR repeat - - - - - - - - - - - - TPR_1,TPR_10,TPR_12,TPR_16,TPR_2,TPR_6,TPR_8 k141_30306_2 1042377.AFPJ01000028_gene2165 7.05e-12 61.6 2DRME@1|root,33C9X@2|Bacteria,1NHQS@1224|Proteobacteria,1SH9S@1236|Gammaproteobacteria,468YE@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_22184_1 218284.CCDN010000002_gene2585 1.08e-101 305.0 COG0457@1|root,COG0457@2|Bacteria,1V0WM@1239|Firmicutes,4HISB@91061|Bacilli,1ZHQF@1386|Bacillus 91061|Bacilli S Tetratricopeptide repeat - - - - - - - - - - - - - k141_22184_2 218284.CCDN010000002_gene2586 7.2e-13 71.6 COG0726@1|root,COG0726@2|Bacteria,1TYRH@1239|Firmicutes,4HEQR@91061|Bacilli,1ZEGM@1386|Bacillus 91061|Bacilli G deacetylase nodB1 - - - - - - - - - - - Cu_amine_oxidN1,Polysacc_deac_1 k141_1848_1 218284.CCDN010000001_gene876 1.33e-96 305.0 COG1196@1|root,COG5283@1|root,COG1196@2|Bacteria,COG5283@2|Bacteria,1UHQM@1239|Firmicutes,4HGW7@91061|Bacilli,1ZBWW@1386|Bacillus 91061|Bacilli D phage tail tape measure protein - - - - - - - - - - - - Peptidase_M23,PhageMin_Tail,SLT k141_23514_1 1121939.L861_10715 1.77e-31 127.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XJHM@135619|Oceanospirillales 135619|Oceanospirillales NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal,dCache_1 k141_29274_1 218284.CCDN010000001_gene1341 3.61e-131 390.0 COG4548@1|root,COG4548@2|Bacteria,1TPW1@1239|Firmicutes,4HCPJ@91061|Bacilli,1ZD6R@1386|Bacillus 91061|Bacilli P Von Willebrand factor yojO - - - - - - - - - - - CobT_C,VWA k141_18788_1 472759.Nhal_1908 2.14e-62 198.0 COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,1S0SN@1236|Gammaproteobacteria,1X0D7@135613|Chromatiales 135613|Chromatiales C it plays a direct role in the translocation of protons across the membrane - - - ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 - - ATP-synt_A k141_18788_2 237368.SCABRO_01374 1.68e-09 54.7 COG0636@1|root,COG0636@2|Bacteria,2J05V@203682|Planctomycetes 203682|Planctomycetes C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation - - - ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_C k141_27195_1 1042377.AFPJ01000030_gene442 6.84e-73 241.0 COG3240@1|root,COG3240@2|Bacteria,1RCCU@1224|Proteobacteria,1S2GX@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Phospholipase lecithinase hemolysin estA GO:0003674,GO:0003824,GO:0016289,GO:0016290,GO:0016787,GO:0016788,GO:0016790,GO:0047617,GO:0052689 - ko:K12686 - - - - ko00000,ko02000,ko02044 1.B.12.8 - - Autotransporter,Lipase_GDSL k141_27195_2 1304874.JAFY01000002_gene788 3.34e-12 64.3 COG1670@1|root,COG1670@2|Bacteria,3TC95@508458|Synergistetes 508458|Synergistetes J Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_3 k141_23515_1 398512.JQKC01000013_gene1458 2.87e-95 281.0 COG0500@1|root,COG0500@2|Bacteria,1TS1P@1239|Firmicutes,24DMF@186801|Clostridia,3WNEF@541000|Ruminococcaceae 186801|Clostridia H Thiopurine S-methyltransferase (TPMT) - - - - - - - - - - - - Methyltransf_11 k141_24589_1 218284.CCDN010000001_gene551 5.41e-205 589.0 COG0072@1|root,COG0072@2|Bacteria,1TP98@1239|Firmicutes,4HAQ9@91061|Bacilli,1ZB8G@1386|Bacillus 91061|Bacilli J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily pheT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - B3_4,B5,FDX-ACB,tRNA_bind k141_22185_1 42565.FP66_07065 3.78e-195 582.0 COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,1RN2W@1236|Gammaproteobacteria,1XHTM@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate gltB - 1.4.1.13,1.4.1.14 ko:K00265 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - GATase_2,GXGXG,Glu_syn_central,Glu_synthase k141_9206_1 1453501.JELR01000001_gene1849 4.66e-08 54.3 COG1215@1|root,COG1215@2|Bacteria,1MWH9@1224|Proteobacteria,1RPTN@1236|Gammaproteobacteria,4647V@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0463 Glycosyltransferases involved in cell wall biogenesis - - 2.4.1.266 ko:K13693 - - - - ko00000,ko01000,ko01003 - GT81 - - k141_9206_2 1042377.AFPJ01000037_gene2984 2.23e-107 320.0 COG3769@1|root,COG3769@2|Bacteria,1NFV5@1224|Proteobacteria,1RR9R@1236|Gammaproteobacteria,464IU@72275|Alteromonadaceae 1236|Gammaproteobacteria S Mannosyl-3-phosphoglycerate phosphatase yedP - 2.7.1.31,3.1.3.70 ko:K07026,ko:K15918 ko00051,ko00260,ko00561,ko00630,ko01100,ko01110,ko01130,ko01200,map00051,map00260,map00561,map00630,map01100,map01110,map01130,map01200 M00532 R01514,R05790 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Hydrolase_3,S6PP k141_9206_3 187303.BN69_3369 1.96e-17 76.6 2C3CF@1|root,32RRR@2|Bacteria,1MZUG@1224|Proteobacteria,2UC1Q@28211|Alphaproteobacteria,370RI@31993|Methylocystaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF3175) - - - - - - - - - - - - DUF3175 k141_29275_1 218284.CCDN010000002_gene2733 1.35e-91 271.0 COG3751@1|root,COG3751@2|Bacteria,1UNHV@1239|Firmicutes,4HEJV@91061|Bacilli,1ZEH2@1386|Bacillus 91061|Bacilli O Prolyl 4-hydroxylase alpha subunit homologues. - - 1.14.11.2 ko:K00472 ko00330,ko01100,map00330,map01100 - R01252 RC00478 ko00000,ko00001,ko01000 - - - 2OG-FeII_Oxy_3 k141_7851_2 1235279.C772_00021 2.8e-108 319.0 COG0559@1|root,COG0559@2|Bacteria,1TR24@1239|Firmicutes,4HBFZ@91061|Bacilli,26EBZ@186818|Planococcaceae 91061|Bacilli U Branched-chain amino acid transport system / permease component - - - ko:K01997 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 k141_34071_1 1294265.JCM21738_1435 3.77e-139 412.0 COG2199@1|root,COG5001@1|root,COG3706@2|Bacteria,COG5001@2|Bacteria,1UI7N@1239|Firmicutes,4ISN0@91061|Bacilli,1ZS9J@1386|Bacillus 91061|Bacilli T diguanylate cyclase - - - - - - - - - - - - GGDEF,MHYT,PAS,PAS_4,PAS_9 k141_31453_1 1042377.AFPJ01000029_gene564 1.36e-49 164.0 COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,1S3WP@1236|Gammaproteobacteria,466WC@72275|Alteromonadaceae 1236|Gammaproteobacteria L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k141_18789_1 406124.ACPC01000020_gene3635 7.61e-62 202.0 COG1226@1|root,COG1226@2|Bacteria,1TS7X@1239|Firmicutes,4HCIB@91061|Bacilli,1ZCD3@1386|Bacillus 91061|Bacilli P COG1226 Kef-type K transport systems yugO - - ko:K10716 - - - - ko00000,ko02000 1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6 - - Ion_trans_2,TrkA_N k141_27197_1 1294265.JCM21738_2401 9.03e-105 307.0 COG4191@1|root,COG4191@2|Bacteria,1UZ9W@1239|Firmicutes,4HDK2@91061|Bacilli,1ZD85@1386|Bacillus 91061|Bacilli T Histidine kinase - - 2.7.13.3 ko:K07697 ko02020,map02020 M00485 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - 5TM-5TMR_LYT,HATPase_c,HisKA k141_14111_1 1279017.AQYJ01000020_gene1322 3.06e-139 406.0 COG0560@1|root,COG0560@2|Bacteria,1MWA3@1224|Proteobacteria,1RNJE@1236|Gammaproteobacteria,4647E@72275|Alteromonadaceae 1236|Gammaproteobacteria E phosphoserine phosphatase serB GO:0000287,GO:0001505,GO:0003674,GO:0003824,GO:0004647,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006563,GO:0006564,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0017144,GO:0019752,GO:0042133,GO:0042136,GO:0042578,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046872,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.3 ko:K01079 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R00582 RC00017 ko00000,ko00001,ko00002,ko01000,ko01009 - - iE2348C_1286.E2348C_4686,iEC042_1314.EC042_4885,iECO26_1355.ECO26_5594,iECSF_1327.ECSF_4321,iECUMN_1333.ECUMN_5012,iETEC_1333.ETEC_4743,iPC815.YPO0442,iUMNK88_1353.UMNK88_5307 ACT_6,HAD,Hydrolase k141_18790_1 1294265.JCM21738_4155 4.35e-23 88.6 COG0690@1|root,COG0690@2|Bacteria,1VK48@1239|Firmicutes,4HR1W@91061|Bacilli,1ZIY2@1386|Bacillus 91061|Bacilli U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation secE - - ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecE k141_7852_1 324602.Caur_3820 3.62e-29 120.0 COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2G7SC@200795|Chloroflexi 200795|Chloroflexi K intracellular signal transduction - - - - - - - - - - - - BTAD,TPR_12 k141_12837_1 1294265.JCM21738_1853 9.95e-114 337.0 COG0477@1|root,COG2814@2|Bacteria,1TRDJ@1239|Firmicutes,4H9Q9@91061|Bacilli,1ZBN7@1386|Bacillus 91061|Bacilli EGP Major facilitator superfamily yuxJ - - - - - - - - - - - MFS_1,Sugar_tr k141_9207_1 218284.CCDN010000002_gene2083 1.23e-131 385.0 COG1541@1|root,COG1541@2|Bacteria,1TQA1@1239|Firmicutes,4HAU0@91061|Bacilli,1ZBRF@1386|Bacillus 91061|Bacilli H Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) paaK - 6.2.1.30 ko:K01912 ko00360,ko01120,ko05111,map00360,map01120,map05111 - R02539 RC00004,RC00014 ko00000,ko00001,ko01000 - - - AMP-binding,AMP-binding_C_2 k141_16197_2 1279017.AQYJ01000019_gene1494 9.86e-48 154.0 COG0268@1|root,COG0268@2|Bacteria,1MZ94@1224|Proteobacteria,1S9AI@1236|Gammaproteobacteria,467QN@72275|Alteromonadaceae 1236|Gammaproteobacteria J Binds directly to 16S ribosomal RNA rpsT GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02968 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S20p k141_16197_3 1279017.AQYJ01000019_gene1495 3.15e-58 199.0 COG0642@1|root,COG0642@2|Bacteria,1QU3Z@1224|Proteobacteria,1T311@1236|Gammaproteobacteria,46D2F@72275|Alteromonadaceae 1236|Gammaproteobacteria T Histidine kinase - - - - - - - - - - - - CBM9_1,HATPase_c,HisKA k141_32750_1 1042377.AFPJ01000042_gene1014 3.56e-71 229.0 COG0154@1|root,COG0154@2|Bacteria,1MWWQ@1224|Proteobacteria,1RMKH@1236|Gammaproteobacteria,466AW@72275|Alteromonadaceae 1236|Gammaproteobacteria J Belongs to the amidase family nylA - 3.5.1.4,6.3.5.6,6.3.5.7 ko:K01426,ko:K02433 ko00330,ko00360,ko00380,ko00627,ko00643,ko00970,ko01100,ko01120,map00330,map00360,map00380,map00627,map00643,map00970,map01100,map01120 - R02540,R03096,R03180,R03905,R03909,R04212,R05551,R05590 RC00010,RC00100,RC00950,RC01025 ko00000,ko00001,ko01000,ko03029 - - - Amidase k141_32750_2 1042377.AFPJ01000042_gene1016 2.55e-275 787.0 COG1629@1|root,COG4771@2|Bacteria,1QV5Q@1224|Proteobacteria,1T4RK@1236|Gammaproteobacteria,46DC8@72275|Alteromonadaceae 1236|Gammaproteobacteria P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec k141_27198_1 665959.HMPREF1013_00810 2.67e-38 147.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1TR2N@1239|Firmicutes,4H9RR@91061|Bacilli,1ZB2Q@1386|Bacillus 91061|Bacilli EU peptidase yuxL - 3.4.19.1 ko:K01303 - - - - ko00000,ko01000,ko01002 - - - PD40,Peptidase_S9 k141_19832_2 218284.CCDN010000010_gene4343 4.42e-62 191.0 COG2163@1|root,COG2163@2|Bacteria,1VEPA@1239|Firmicutes,4HJQF@91061|Bacilli,1ZHSH@1386|Bacillus 91061|Bacilli J COG2163 Ribosomal protein L14E L6E L27E - - - - - - - - - - - - KOW k141_30307_1 1479235.KK366039_gene2992 3.29e-114 339.0 COG0642@1|root,COG2205@2|Bacteria,1QV1H@1224|Proteobacteria,1T4NM@1236|Gammaproteobacteria 1236|Gammaproteobacteria T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA k141_18792_1 218284.CCDN010000002_gene2096 4.37e-119 347.0 COG2070@1|root,COG2070@2|Bacteria,1TPC3@1239|Firmicutes,4H9T0@91061|Bacilli,1ZBRG@1386|Bacillus 91061|Bacilli S COG2070 Dioxygenases related to 2-nitropropane dioxygenase fabK - 1.3.1.9 ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00083 R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765 RC00052,RC00076 ko00000,ko00001,ko00002,ko01000,ko01004 - - - NMO k141_7853_1 218284.CCDN010000002_gene2884 2.83e-114 337.0 COG1073@1|root,COG1073@2|Bacteria,1TQYU@1239|Firmicutes,4HC4H@91061|Bacilli,1ZBDV@1386|Bacillus 91061|Bacilli S COG1073 Hydrolases of the alpha beta superfamily - - - ko:K06889 - - - - ko00000 - - - Hydrolase_4 k141_27199_1 1294265.JCM21738_1920 1.02e-83 247.0 COG2346@1|root,COG2346@2|Bacteria,1V6JN@1239|Firmicutes,4HHQG@91061|Bacilli,1ZG81@1386|Bacillus 91061|Bacilli S COG2346 Truncated hemoglobins yjbI - - ko:K06886 - - - - ko00000 - - - Bac_globin k141_876_2 1279017.AQYJ01000028_gene2197 0.0 1368.0 COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,1RP9N@1236|Gammaproteobacteria,464DC@72275|Alteromonadaceae 1236|Gammaproteobacteria H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell glnE GO:0000166,GO:0000287,GO:0000820,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006521,GO:0006541,GO:0006542,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0008882,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0010565,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0019222,GO:0019752,GO:0030554,GO:0031323,GO:0032553,GO:0032555,GO:0032559,GO:0033238,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.42,2.7.7.89 ko:K00982 - - - - ko00000,ko01000 - - - GlnD_UR_UTase,GlnE k141_876_3 1042377.AFPJ01000024_gene783 0.0 1022.0 COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,4662Z@72275|Alteromonadaceae 1236|Gammaproteobacteria NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB gspE - - ko:K02454 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSE,T2SSE_N k141_876_4 1453501.JELR01000002_gene641 5.6e-131 375.0 COG1392@1|root,COG1392@2|Bacteria,1MXY9@1224|Proteobacteria,1RQHT@1236|Gammaproteobacteria,466IF@72275|Alteromonadaceae 1236|Gammaproteobacteria P Protein of unknown function DUF47 UF78_21250 - - ko:K07220 - - - - ko00000 - - - PhoU_div k141_6772_1 1042377.AFPJ01000034_gene2398 1.92e-27 113.0 COG1426@1|root,COG1426@2|Bacteria,1N240@1224|Proteobacteria,1RQMV@1236|Gammaproteobacteria,4689I@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria rodZ GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944 - ko:K15539 - - - - ko00000 - - - DUF4115,HTH_25 k141_6772_2 1279017.AQYJ01000023_gene3139 2.45e-121 354.0 COG3063@1|root,COG3063@2|Bacteria,1RAFJ@1224|Proteobacteria,1S5H6@1236|Gammaproteobacteria,467DR@72275|Alteromonadaceae 1236|Gammaproteobacteria NU COG3063 Tfp pilus assembly protein PilF pilF - - ko:K02656 - - - - ko00000,ko02035,ko02044 - - - TPR_12,TPR_16,TPR_19,TPR_2,TPR_8 k141_6772_6 1279017.AQYJ01000023_gene3133 1.22e-68 208.0 COG0633@1|root,COG0633@2|Bacteria,1RHDC@1224|Proteobacteria,1S5XW@1236|Gammaproteobacteria,4674E@72275|Alteromonadaceae 1236|Gammaproteobacteria C 2Fe-2S iron-sulfur cluster binding domain fdx - - ko:K04755 - - - - ko00000 - - - Fer2 k141_6772_7 1279017.AQYJ01000023_gene3132 0.0 1006.0 COG0443@1|root,COG0443@2|Bacteria,1MVQI@1224|Proteobacteria,1RN74@1236|Gammaproteobacteria,464TI@72275|Alteromonadaceae 1236|Gammaproteobacteria O Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB hscA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0010467,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0050896,GO:0051604,GO:0051716,GO:0070417,GO:0071704,GO:0097159,GO:0097367,GO:0097428,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1990230,GO:1990234 - ko:K04044 - - - - ko00000,ko03110 1.A.33 - - HSP70 k141_6772_8 1453501.JELR01000001_gene3023 6.23e-75 229.0 COG1076@1|root,COG1076@2|Bacteria,1RHZX@1224|Proteobacteria,1S9YH@1236|Gammaproteobacteria,4680Q@72275|Alteromonadaceae 1236|Gammaproteobacteria O Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA hscB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051604,GO:0071704,GO:0097428,GO:1901564,GO:1902494,GO:1990230,GO:1990234 - ko:K04082 - - - - ko00000,ko03029,ko03110 - - - DnaJ,HSCB_C k141_6772_9 1453501.JELR01000001_gene3024 8.8e-62 190.0 COG0316@1|root,COG0316@2|Bacteria,1RH6T@1224|Proteobacteria,1S5XD@1236|Gammaproteobacteria,4677E@72275|Alteromonadaceae 1236|Gammaproteobacteria S Is able to transfer iron-sulfur clusters to apo- ferredoxin. Multiple cycles of 2Fe2S cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system iscA GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016043,GO:0016226,GO:0016530,GO:0019538,GO:0022607,GO:0031163,GO:0034986,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051540,GO:0051604,GO:0071704,GO:0071840,GO:0097428,GO:0140104,GO:1901564 - ko:K05997,ko:K13628 - - - - ko00000,ko03016 - - iAPECO1_1312.APECO1_3997,iB21_1397.B21_02384,iBWG_1329.BWG_2292,iE2348C_1286.E2348C_2811,iEC042_1314.EC042_2732,iEC55989_1330.EC55989_2813,iECABU_c1320.ECABU_c28340,iECBD_1354.ECBD_1156,iECB_1328.ECB_02420,iECDH10B_1368.ECDH10B_2695,iECD_1391.ECD_02420,iECED1_1282.ECED1_2959,iECIAI1_1343.ECIAI1_2580,iECIAI39_1322.ECIAI39_2729,iECNA114_1301.ECNA114_2607,iECO103_1326.ECO103_3045,iECO111_1330.ECO111_3252,iECO26_1355.ECO26_3575,iECOK1_1307.ECOK1_2877,iECP_1309.ECP_2533,iECS88_1305.ECS88_2704,iECSE_1348.ECSE_2814,iECSF_1327.ECSF_2372,iECSP_1301.ECSP_3472,iECUMN_1333.ECUMN_2848,iECW_1372.ECW_m2754,iECs_1301.ECs3394,iEKO11_1354.EKO11_1205,iETEC_1333.ETEC_2685,iEcDH1_1363.EcDH1_1140,iEcSMS35_1347.EcSMS35_2681,iEcolC_1368.EcolC_1149,iG2583_1286.G2583_3058,iJO1366.b2528,iLF82_1304.LF82_1120,iNRG857_1313.NRG857_12580,iSBO_1134.SBO_2552,iSDY_1059.SDY_2724,iSF_1195.SF2575,iSSON_1240.SSON_2610,iS_1188.S2747,iUMN146_1321.UM146_04060,iUMNK88_1353.UMNK88_3181,iWFL_1372.ECW_m2754,iY75_1357.Y75_RS13195,iZ_1308.Z3795,ic_1306.c3053 Fe-S_biosyn k141_6772_10 1279017.AQYJ01000023_gene3129 5.17e-82 244.0 COG0822@1|root,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,1S3P1@1236|Gammaproteobacteria,466TH@72275|Alteromonadaceae 1236|Gammaproteobacteria C A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters iscU GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016043,GO:0016226,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0022607,GO:0030003,GO:0031163,GO:0036455,GO:0042592,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0071840,GO:0097428,GO:0098771,GO:1901564 - ko:K04488 - - - - ko00000 - - iAPECO1_1312.APECO1_3996,iB21_1397.B21_02385,iBWG_1329.BWG_2293,iE2348C_1286.E2348C_2812,iEC042_1314.EC042_2733,iEC55989_1330.EC55989_2814,iECABU_c1320.ECABU_c28350,iECBD_1354.ECBD_1155,iECB_1328.ECB_02421,iECDH10B_1368.ECDH10B_2696,iECDH1ME8569_1439.ECDH1ME8569_2456,iECD_1391.ECD_02421,iECED1_1282.ECED1_2960,iECH74115_1262.ECH74115_3761,iECIAI1_1343.ECIAI1_2581,iECIAI39_1322.ECIAI39_2730,iECNA114_1301.ECNA114_2608,iECO103_1326.ECO103_3046,iECO111_1330.ECO111_3253,iECO26_1355.ECO26_3576,iECOK1_1307.ECOK1_2878,iECP_1309.ECP_2534,iECS88_1305.ECS88_2705,iECSE_1348.ECSE_2815,iECSF_1327.ECSF_2373,iECSP_1301.ECSP_3473,iECUMN_1333.ECUMN_2849,iECW_1372.ECW_m2755,iECs_1301.ECs3395,iEKO11_1354.EKO11_1204,iETEC_1333.ETEC_2686,iEcDH1_1363.EcDH1_1139,iEcE24377_1341.EcE24377A_2814,iEcHS_1320.EcHS_A2680,iEcSMS35_1347.EcSMS35_2682,iEcolC_1368.EcolC_1148,iG2583_1286.G2583_3059,iJO1366.b2529,iSDY_1059.SDY_2725,iSFV_1184.SFV_2577,iSF_1195.SF2576,iSFxv_1172.SFxv_2832,iSSON_1240.SSON_2611,iS_1188.S2748,iUMN146_1321.UM146_04055,iUMNK88_1353.UMNK88_3182,iUTI89_1310.UTI89_C2851,iWFL_1372.ECW_m2755,iY75_1357.Y75_RS13200,iZ_1308.Z3796,ic_1306.c3055 NifU_N k141_6772_11 1453501.JELR01000001_gene3026 1.84e-270 743.0 COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,1RNCD@1236|Gammaproteobacteria,4647T@72275|Alteromonadaceae 1236|Gammaproteobacteria E Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins iscS GO:0001522,GO:0003674,GO:0003824,GO:0004123,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006790,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009000,GO:0009058,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016226,GO:0016740,GO:0016769,GO:0016782,GO:0016783,GO:0016829,GO:0016846,GO:0018130,GO:0018131,GO:0019842,GO:0022607,GO:0030170,GO:0031071,GO:0031119,GO:0031163,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046484,GO:0048037,GO:0050662,GO:0051186,GO:0070279,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097163,GO:0140104,GO:1901360,GO:1901363 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - iPC815.YPO2896,iYL1228.KPN_02862 Aminotran_5 k141_6772_14 1279017.AQYJ01000023_gene3125 5.81e-179 499.0 COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,1RNME@1236|Gammaproteobacteria,464K2@72275|Alteromonadaceae 1236|Gammaproteobacteria G COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family suhB - 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 - - - Inositol_P k141_14113_1 926550.CLDAP_24920 4.08e-47 161.0 COG0451@1|root,COG0451@2|Bacteria,2G8B1@200795|Chloroflexi 200795|Chloroflexi GM Polysaccharide biosynthesis protein - - - - - - - - - - - - Epimerase k141_34072_1 218284.CCDN010000006_gene3626 6.73e-45 159.0 COG0745@1|root,COG2199@1|root,COG0745@2|Bacteria,COG3706@2|Bacteria,1TSW8@1239|Firmicutes,4HBT1@91061|Bacilli,1ZCZQ@1386|Bacillus 91061|Bacilli T diguanylate cyclase - - - - - - - - - - - - GGDEF,Hpt,Response_reg k141_19833_1 768066.HELO_3955 8.12e-20 84.3 COG3485@1|root,COG3485@2|Bacteria,1MV3B@1224|Proteobacteria,1RPUS@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q protocatechuate 3,4-dioxygenase pcaG - 1.13.11.3 ko:K00448 ko00362,ko00624,ko01100,ko01120,ko01220,map00362,map00624,map01100,map01120,map01220 - R01631,R03549 RC00388,RC00953 br01602,ko00000,ko00001,ko01000 - - - Dioxygenase_C k141_19833_2 768066.HELO_3956 5.63e-122 352.0 COG3485@1|root,COG3485@2|Bacteria,1MUYX@1224|Proteobacteria,1RQHU@1236|Gammaproteobacteria,1XM91@135619|Oceanospirillales 135619|Oceanospirillales Q Protocatechuate 3,4-dioxygenase beta subunit N terminal - - 1.13.11.3 ko:K00449 ko00362,ko00624,ko01100,ko01120,ko01220,map00362,map00624,map01100,map01120,map01220 - R01631,R03549 RC00388,RC00953 br01602,ko00000,ko00001,ko01000 - - - Dioxygenase_C,PCDO_beta_N k141_31466_3 1279017.AQYJ01000024_gene1022 1.04e-123 379.0 COG1835@1|root,COG1835@2|Bacteria,1MV2W@1224|Proteobacteria,1RQS2@1236|Gammaproteobacteria,465QX@72275|Alteromonadaceae 1236|Gammaproteobacteria I Acyltransferase - - - - - - - - - - - - Acyl_transf_3 k141_882_1 491915.Aflv_2667 2.64e-89 276.0 COG1004@1|root,COG1004@2|Bacteria,1TQFN@1239|Firmicutes,4HADP@91061|Bacilli,21WA2@150247|Anoxybacillus 91061|Bacilli M UDP binding domain - - 1.1.1.22 ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 M00014,M00129,M00361,M00362 R00286 RC00291 ko00000,ko00001,ko00002,ko01000 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N k141_34084_1 218284.CCDN010000001_gene1434 1.37e-32 119.0 2CC31@1|root,2Z920@2|Bacteria,1UZSZ@1239|Firmicutes,4HCVB@91061|Bacilli,1ZGJ7@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_34084_2 1243664.CAVL020000015_gene1920 3.7e-44 149.0 COG0708@1|root,COG0708@2|Bacteria,1TPFB@1239|Firmicutes,4HAIU@91061|Bacilli,1ZAS3@1386|Bacillus 91061|Bacilli L exodeoxyribonuclease III exoA GO:0003674,GO:0003824,GO:0003906,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008296,GO:0008309,GO:0008311,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.11.2 ko:K01142 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Exo_endo_phos k141_22223_2 1116375.VEJY3_06125 2.42e-253 721.0 COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,1RQX2@1236|Gammaproteobacteria,1XU87@135623|Vibrionales 135623|Vibrionales C COG0277 FAD FMN-containing dehydrogenases ydiJ - - - - - - - - - - - FAD-oxidase_C,FAD_binding_4,Fer4_8 k141_19861_1 1279017.AQYJ01000023_gene3109 9.49e-138 403.0 COG2925@1|root,COG2925@2|Bacteria,1MV0U@1224|Proteobacteria,1RM85@1236|Gammaproteobacteria,464RJ@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG2925 Exonuclease I sbcB GO:0000175,GO:0000287,GO:0000738,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004532,GO:0004536,GO:0004540,GO:0005488,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0008852,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016829,GO:0016835,GO:0016895,GO:0016896,GO:0019439,GO:0034641,GO:0034655,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0046872,GO:0051575,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0140097,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575 3.1.11.1 ko:K01141 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_X-T_C,RNase_T k141_32770_2 946235.CAER01000008_gene388 1.54e-125 373.0 COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,4HAPA@91061|Bacilli,23MTZ@182709|Oceanobacillus 91061|Bacilli C Iron-containing alcohol dehydrogenase - - - - - - - - - - - - Fe-ADH k141_23554_1 1382358.JHVN01000013_gene1825 5.47e-66 214.0 COG2017@1|root,COG2017@2|Bacteria,1TQGJ@1239|Firmicutes,4HADZ@91061|Bacilli,21V10@150247|Anoxybacillus 91061|Bacilli G Aldose 1-epimerase mro - 5.1.3.3 ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 M00632 R01602,R10619 RC00563 ko00000,ko00001,ko00002,ko01000 - - - Aldose_epim k141_22224_1 265729.GS18_0208090 7.29e-41 137.0 COG0477@1|root,COG2814@2|Bacteria,1VGN4@1239|Firmicutes,4HNVP@91061|Bacilli,1ZIWN@1386|Bacillus 91061|Bacilli EGP Domain of unknown function (DUF3817) ydzA GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - - - - - - - - - - DUF3817 k141_9239_2 1120950.KB892771_gene1330 1.54e-73 232.0 COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,4DNMI@85009|Propionibacteriales 201174|Actinobacteria I Belongs to the thiolase family - - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N k141_37497_1 218284.CCDN010000005_gene3373 1.56e-96 291.0 COG0436@1|root,COG0436@2|Bacteria,1TQD6@1239|Firmicutes,4HAHQ@91061|Bacilli,1ZBB2@1386|Bacillus 91061|Bacilli E Aminotransferase mtnE - - ko:K08969 ko00270,ko01100,map00270,map01100 M00034 R07396 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k141_14980_1 218284.CCDN010000010_gene4336 9.15e-22 91.3 COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,4HA7T@91061|Bacilli,1ZBBK@1386|Bacillus 91061|Bacilli P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates ecfA2 GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0008150,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085 - ko:K16787 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran k141_14980_2 218284.CCDN010000010_gene4335 1.75e-163 460.0 COG0619@1|root,COG0619@2|Bacteria,1TQ0E@1239|Firmicutes,4H9VT@91061|Bacilli,1ZBNS@1386|Bacillus 91061|Bacilli P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates ecfT - - ko:K16785 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - CbiQ k141_15130_2 223926.28806246 0.0 1097.0 COG0281@1|root,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,1RQ11@1236|Gammaproteobacteria,1XTTY@135623|Vibrionales 135623|Vibrionales C malic enzyme maeA GO:0003674,GO:0003824,GO:0004470,GO:0004473,GO:0006082,GO:0006090,GO:0006108,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0019752,GO:0032787,GO:0043436,GO:0043648,GO:0044237,GO:0044281,GO:0055114,GO:0071704 1.1.1.38 ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 - R00214 RC00105 ko00000,ko00001,ko01000 - - - Malic_M,malic k141_15130_3 1116375.VEJY3_06075 0.0 1300.0 COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,1RPJX@1236|Gammaproteobacteria,1XSRF@135623|Vibrionales 135623|Vibrionales L COG1643 HrpA-like helicases - - - - - - - - - - - - DEAD,HA2,Helicase_C k141_15130_4 223926.28806248 6.87e-179 499.0 COG2829@1|root,COG2829@2|Bacteria,1PC8I@1224|Proteobacteria,1RMJH@1236|Gammaproteobacteria,1XTPQ@135623|Vibrionales 135623|Vibrionales M Outer membrane phospholipase A pldA - 3.1.1.32,3.1.1.4 ko:K01058 ko00564,ko00565,ko00590,ko00591,ko00592,ko01100,ko01110,map00564,map00565,map00590,map00591,map00592,map01100,map01110 - R01315,R01316,R01317,R02053,R02054,R04034,R07064,R07379,R07387,R07859,R07860 RC00020,RC00037,RC00041,RC00094 ko00000,ko00001,ko01000 - - - PLA1 k141_15130_6 223926.28806251 2.3e-55 182.0 COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,1RNNY@1236|Gammaproteobacteria,1XUUI@135623|Vibrionales 135623|Vibrionales F Belongs to the SAICAR synthetase family purC GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04591 RC00064,RC00162 ko00000,ko00001,ko00002,ko01000 - - - SAICAR_synt k141_20062_1 1283337.B0ZSH3_BPHA1 4.29e-78 243.0 4QH23@10239|Viruses,4R0NS@35237|dsDNA viruses no RNA stage,4QQX9@28883|Caudovirales,4QIAR@10662|Myoviridae 10662|Myoviridae S Phage late control gene D protein (GPD) - - - - - - - - - - - - - k141_29469_1 218284.CCDN010000005_gene3335 1.51e-216 600.0 COG0208@1|root,COG0208@2|Bacteria,1TQTH@1239|Firmicutes,4H9WX@91061|Bacilli,1ZBBM@1386|Bacillus 91061|Bacilli F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdB - 1.17.4.1 ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_sm k141_21020_3 218284.CCDN010000001_gene755 1.09e-170 477.0 COG1381@1|root,COG1381@2|Bacteria,1UZ19@1239|Firmicutes,4HAHI@91061|Bacilli,1ZAUA@1386|Bacillus 91061|Bacilli L Involved in DNA repair and RecF pathway recombination recO GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - ko:K03584 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecO_C,RecO_N k141_17455_1 315730.BcerKBAB4_1940 2.02e-85 256.0 COG1670@1|root,COG1670@2|Bacteria,1V3W1@1239|Firmicutes,4HH6A@91061|Bacilli,1ZG7V@1386|Bacillus 91061|Bacilli J Acetyltransferase (GNAT) domain speG - - - - - - - - - - - Acetyltransf_3 k141_17455_2 218284.CCDN010000004_gene3051 1.23e-89 270.0 COG0398@1|root,COG0398@2|Bacteria,1V3J1@1239|Firmicutes,4HHXX@91061|Bacilli,1ZEPX@1386|Bacillus 91061|Bacilli S SNARE associated Golgi protein ytxB - - - - - - - - - - - SNARE_assoc k141_28082_1 218284.CCDN010000001_gene1594 2.25e-130 375.0 COG2362@1|root,COG2362@2|Bacteria,1TSUZ@1239|Firmicutes,4HC5R@91061|Bacilli,1ZC41@1386|Bacillus 91061|Bacilli E D-aminopeptidase dppA - - ko:K16203 - - - - ko00000,ko01000,ko01002 3.A.1.5.2 - iYO844.BSU12920 Peptidase_M55 k141_22475_1 223184.AS25_13085 7.72e-30 113.0 COG1846@1|root,COG1846@2|Bacteria,2IMA9@201174|Actinobacteria,1W9PB@1268|Micrococcaceae 201174|Actinobacteria K transcriptional regulator - - - - - - - - - - - - MarR k141_22475_2 1117647.M5M_08600 2.91e-85 254.0 COG0386@1|root,COG0386@2|Bacteria,1RD1R@1224|Proteobacteria,1S425@1236|Gammaproteobacteria,1J6CW@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O Belongs to the glutathione peroxidase family gpo - 1.11.1.9 ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 - R00274,R07034,R07035 RC00011,RC00982 ko00000,ko00001,ko01000 - - - GSHPx k141_22475_3 1279017.AQYJ01000022_gene2584 7.08e-264 746.0 COG0672@1|root,COG2010@1|root,COG0672@2|Bacteria,COG2010@2|Bacteria,1MXHM@1224|Proteobacteria,1RMWB@1236|Gammaproteobacteria,4661C@72275|Alteromonadaceae 1236|Gammaproteobacteria C Iron permease FTR1 family efeU_1 - - ko:K07243 - - - - ko00000,ko02000 2.A.108.1,2.A.108.2 - - Cytochrome_CBB3,FTR1 k141_22475_5 1279017.AQYJ01000029_gene3503 2.64e-84 257.0 COG2885@1|root,COG2885@2|Bacteria,1R9HA@1224|Proteobacteria,1RYNB@1236|Gammaproteobacteria,46795@72275|Alteromonadaceae 1236|Gammaproteobacteria M OmpA family - - - - - - - - - - - - OmpA k141_22475_6 1453501.JELR01000005_gene1619 1.96e-47 174.0 COG0497@1|root,COG0497@2|Bacteria,1PAB3@1224|Proteobacteria,1RZB5@1236|Gammaproteobacteria,468PN@72275|Alteromonadaceae 1236|Gammaproteobacteria L DNA recombination - - - - - - - - - - - - - k141_37686_3 1279017.AQYJ01000028_gene2083 3.71e-100 296.0 COG3637@1|root,COG3637@2|Bacteria,1RDPZ@1224|Proteobacteria,1S4GQ@1236|Gammaproteobacteria,467IM@72275|Alteromonadaceae 1236|Gammaproteobacteria M Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - - - - - - - - - - OMP_b-brl k141_37686_4 1042377.AFPJ01000028_gene2155 7.9e-116 340.0 COG3637@1|root,COG3637@2|Bacteria,1QXK4@1224|Proteobacteria,1T3DI@1236|Gammaproteobacteria,46752@72275|Alteromonadaceae 1236|Gammaproteobacteria M Bacterial SH3 domain - - - - - - - - - - - - OMP_b-brl,SH3_3,SH3_4 k141_37686_5 1453501.JELR01000002_gene1336 2.16e-265 754.0 COG0823@1|root,COG0823@2|Bacteria,1R3VN@1224|Proteobacteria,1RNKG@1236|Gammaproteobacteria,46408@72275|Alteromonadaceae 1236|Gammaproteobacteria U COG0823 Periplasmic component of the Tol biopolymer transport system - - - - - - - - - - - - PD40 k141_24784_1 1231057.AMGD01000031_gene1829 5.8e-12 65.9 COG0591@1|root,COG0591@2|Bacteria,1TRYH@1239|Firmicutes,4HE2W@91061|Bacilli,26F1I@186818|Planococcaceae 91061|Bacilli E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - - - - - - - - - - SSF k141_24784_2 406124.ACPC01000049_gene85 1.71e-169 479.0 29RNN@1|root,30CRY@2|Bacteria,1UP6P@1239|Firmicutes,4HBII@91061|Bacilli,1ZF3C@1386|Bacillus 91061|Bacilli S DoxX-like family yndG - - - - - - - - - - - DoxX_3 k141_24784_3 1121090.KB894710_gene1465 8.67e-06 46.6 arCOG11972@1|root,2ZG4P@2|Bacteria,1V2DB@1239|Firmicutes,4HGUW@91061|Bacilli,1ZGP4@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF4166) - - - - - - - - - - - - DUF4166 k141_2034_1 1279017.AQYJ01000029_gene3779 3.27e-56 186.0 COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria,463YA@72275|Alteromonadaceae 1236|Gammaproteobacteria I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP fabF GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033817,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.179 ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - iAF1260.b1095,iAPECO1_1312.APECO1_176,iB21_1397.B21_01099,iBWG_1329.BWG_0943,iE2348C_1286.E2348C_1187,iEC042_1314.EC042_1165,iEC55989_1330.EC55989_1207,iECABU_c1320.ECABU_c13085,iECBD_1354.ECBD_2506,iECB_1328.ECB_01091,iECDH10B_1368.ECDH10B_1167,iECDH1ME8569_1439.ECDH1ME8569_1030,iECD_1391.ECD_01091,iECED1_1282.ECED1_1238,iECH74115_1262.ECH74115_1474,iECIAI1_1343.ECIAI1_1130,iECIAI39_1322.ECIAI39_2066,iECO103_1326.ECO103_1140,iECO111_1330.ECO111_1372,iECO26_1355.ECO26_1428,iECOK1_1307.ECOK1_1202,iECP_1309.ECP_1087,iECS88_1305.ECS88_1109,iECSE_1348.ECSE_1159,iECSF_1327.ECSF_0994,iECSP_1301.ECSP_1396,iECUMN_1333.ECUMN_1270,iECW_1372.ECW_m1203,iECs_1301.ECs1473,iEKO11_1354.EKO11_2739,iETEC_1333.ETEC_1160,iEcDH1_1363.EcDH1_2552,iEcE24377_1341.EcE24377A_1216,iEcSMS35_1347.EcSMS35_2032,iG2583_1286.G2583_1355,iJO1366.b1095,iJR904.b1095,iLF82_1304.LF82_0607,iNRG857_1313.NRG857_05280,iSF_1195.SF1099,iSFxv_1172.SFxv_1251,iS_1188.S1179,iUMN146_1321.UM146_11850,iWFL_1372.ECW_m1203,iY75_1357.Y75_RS05720,iZ_1308.Z1734,ic_1306.c1365 Ketoacyl-synt_C,ketoacyl-synt k141_9489_1 218284.CCDN010000002_gene2006 4.31e-80 247.0 COG0548@1|root,COG0548@2|Bacteria,1TP0N@1239|Firmicutes,4HH91@91061|Bacilli,1ZF3H@1386|Bacillus 91061|Bacilli E Belongs to the acetylglutamate kinase family. ArgB subfamily argB GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R02649 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase k141_9489_2 265729.GS18_0200125 9.51e-34 127.0 COG1364@1|root,COG1364@2|Bacteria,1TPBP@1239|Firmicutes,4H9TQ@91061|Bacilli,1ZAU3@1386|Bacillus 91061|Bacilli E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate argJ GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R00259,R02282 RC00004,RC00064 ko00000,ko00001,ko00002,ko01000 - - - ArgJ k141_22515_1 218284.CCDN010000001_gene42 2.95e-155 437.0 COG0631@1|root,COG0631@2|Bacteria,1V6K5@1239|Firmicutes,4HCDR@91061|Bacilli,1ZCYC@1386|Bacillus 91061|Bacilli T phosphatase stp - 3.1.3.16 ko:K20074 - - - - ko00000,ko01000,ko01009 - - - PP2C,PP2C_2 k141_30432_1 1196031.ALEG01000005_gene5684 3.19e-126 363.0 COG1738@1|root,COG1738@2|Bacteria,1TSAY@1239|Firmicutes,4HB9T@91061|Bacilli,1ZEKB@1386|Bacillus 91061|Bacilli S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage ypdP - - ko:K09125 - - - - ko00000 - - - Vut_1 k141_30432_2 218284.CCDN010000001_gene1181 8.48e-17 77.4 COG0328@1|root,COG0328@2|Bacteria,1V3K2@1239|Firmicutes,4HE8H@91061|Bacilli,1ZDMZ@1386|Bacillus 91061|Bacilli L COG0328 Ribonuclease HI ypeP - 3.1.26.4 ko:K03469 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RVT_3 k141_33000_1 1384049.CD29_07055 1.37e-109 328.0 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli,3IX1R@400634|Lysinibacillus 91061|Bacilli C Catalyzes the oxidation of acetaldehyde, benzaldehyde, propionaldehyde and other aldehydes acoD - - ko:K00138 ko00010,ko00620,ko01100,ko01110,ko01120,map00010,map00620,map01100,map01110,map01120 - R00711 RC00047 ko00000,ko00001,ko01000 - - - Aldedh k141_29494_1 1279017.AQYJ01000021_gene2847 7.83e-54 173.0 COG0350@1|root,COG0350@2|Bacteria,1N2YQ@1224|Proteobacteria,1S68H@1236|Gammaproteobacteria,467W5@72275|Alteromonadaceae 1236|Gammaproteobacteria L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated ogt - 2.1.1.63 ko:K00567 - - - - ko00000,ko01000,ko03400 - - - DNA_binding_1,Methyltransf_1N k141_17493_1 279010.BL01871 2.9e-92 270.0 COG0394@1|root,COG0394@2|Bacteria,1V3JW@1239|Firmicutes,4HH49@91061|Bacilli,1ZFM2@1386|Bacillus 91061|Bacilli T Catalyzes the reduction of arsenate As(V) to arsenite As(III) arsC GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008794,GO:0016491,GO:0030611,GO:0030613,GO:0030614,GO:0042221,GO:0046685,GO:0050896,GO:0055114 1.20.4.1 ko:K03741 - - - - ko00000,ko01000 - - - LMWPc k141_5845_1 768066.HELO_4338 2.45e-82 264.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XHNA@135619|Oceanospirillales 135619|Oceanospirillales T Methyl-accepting chemotaxis - - - ko:K03406,ko:K03776 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal,PAS_3,TarH k141_5845_2 42565.FP66_08370 1.69e-20 89.7 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria 1236|Gammaproteobacteria NT chemotaxis, protein tap GO:0001101,GO:0001932,GO:0003674,GO:0004888,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006928,GO:0006935,GO:0007154,GO:0007165,GO:0007172,GO:0008104,GO:0008150,GO:0009593,GO:0009605,GO:0009719,GO:0009893,GO:0009966,GO:0009987,GO:0010033,GO:0010243,GO:0010604,GO:0010646,GO:0016020,GO:0016021,GO:0016043,GO:0019220,GO:0019222,GO:0019899,GO:0019900,GO:0019901,GO:0022607,GO:0023051,GO:0023052,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031399,GO:0031401,GO:0032101,GO:0032110,GO:0032268,GO:0032270,GO:0032879,GO:0032991,GO:0033036,GO:0034613,GO:0034622,GO:0038023,GO:0040011,GO:0040012,GO:0042221,GO:0042325,GO:0042330,GO:0042802,GO:0042803,GO:0043113,GO:0043200,GO:0043424,GO:0043549,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045859,GO:0046983,GO:0048518,GO:0048522,GO:0048583,GO:0048870,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0050920,GO:0051171,GO:0051173,GO:0051174,GO:0051179,GO:0051246,GO:0051247,GO:0051259,GO:0051260,GO:0051270,GO:0051338,GO:0051606,GO:0051641,GO:0051668,GO:0051674,GO:0051716,GO:0060089,GO:0060255,GO:0065003,GO:0065007,GO:0065009,GO:0070727,GO:0070887,GO:0071229,GO:0071230,GO:0071310,GO:0071417,GO:0071495,GO:0071840,GO:0071944,GO:0072657,GO:0080090,GO:0098561,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901873,GO:1901875,GO:1902021,GO:2000145 - ko:K03406,ko:K05874,ko:K05875,ko:K05876,ko:K05877 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal,TarH k141_16421_2 1453501.JELR01000002_gene1161 3.42e-64 201.0 COG0625@1|root,COG0625@2|Bacteria,1MY47@1224|Proteobacteria,1RRI3@1236|Gammaproteobacteria,467CI@72275|Alteromonadaceae 1236|Gammaproteobacteria O Glutathione S-transferase, C-terminal domain - - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C,GST_C_2,GST_C_3,GST_N,GST_N_2,GST_N_3 k141_28112_1 1042377.AFPJ01000043_gene852 2.44e-43 148.0 2DBQ1@1|root,2ZABN@2|Bacteria,1R83J@1224|Proteobacteria,1T169@1236|Gammaproteobacteria,46BUW@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_26116_1 1116375.VEJY3_07310 3.21e-111 325.0 COG5473@1|root,COG5473@2|Bacteria,1N3T0@1224|Proteobacteria,1SEVY@1236|Gammaproteobacteria,1XTIE@135623|Vibrionales 135623|Vibrionales - - VP1530 - - - - - - - - - - - - k141_9490_1 562743.JH976435_gene3191 1.6e-77 246.0 COG0477@1|root,COG2814@2|Bacteria,1TQEW@1239|Firmicutes,4HASU@91061|Bacilli 91061|Bacilli EGP Major facilitator superfamily ymfD - - ko:K08221 - - - - ko00000,ko02000 2.A.1.32 - - MFS_1,MFS_2,Sugar_tr k141_17494_1 218284.CCDN010000001_gene1145 9.84e-73 229.0 COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,4HA13@91061|Bacilli,1ZCMB@1386|Bacillus 91061|Bacilli E Aminotransferase aspB GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769,GO:0047297 2.6.1.1,2.6.1.14 ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 - R00355,R00694,R00734,R00896,R01346,R02433,R02619,R05052 RC00006,RC00025 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 k141_21047_1 218284.CCDN010000005_gene3176 2.3e-75 229.0 COG1846@1|root,COG1846@2|Bacteria,1UY04@1239|Firmicutes,4HBQS@91061|Bacilli,1ZBRK@1386|Bacillus 91061|Bacilli K Negative regulator of protease production and sporulation hpr GO:0000003,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - ko:K09682 - - - - ko00000,ko03000 - - - MarR k141_20103_1 698769.JFBD01000012_gene2298 5.32e-75 229.0 COG0494@1|root,COG0494@2|Bacteria,1V6F5@1239|Firmicutes,4HII9@91061|Bacilli,4C5CX@84406|Virgibacillus 91061|Bacilli L NUDIX domain nudF - 3.6.1.13 ko:K01515 ko00230,map00230 - R01054 RC00002 ko00000,ko00001,ko01000 - - iSB619.SA_RS07540,iYO844.BSU23610 NUDIX k141_20103_2 1246484.D479_19229 1.58e-05 45.8 COG0667@1|root,COG0667@2|Bacteria,1TTT8@1239|Firmicutes,4H9XM@91061|Bacilli,3NEIW@45667|Halobacillus 91061|Bacilli C Aldo/keto reductase family yqkF - - - - - - - - - - - Aldo_ket_red k141_15148_2 218284.CCDN010000007_gene3802 2.31e-86 259.0 COG1811@1|root,COG1811@2|Bacteria,1UH19@1239|Firmicutes,4HB4E@91061|Bacilli,1ZBSK@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF554) ydfK - - ko:K07150 - - - - ko00000 - - - DUF554 k141_1127_2 1279017.AQYJ01000024_gene1108 2.58e-237 658.0 COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,1RNCW@1236|Gammaproteobacteria,465GF@72275|Alteromonadaceae 1236|Gammaproteobacteria S flavoproteins yhiN GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K07007 - - - - ko00000 - - - HI0933_like k141_4488_1 218284.CCDN010000002_gene2006 2.78e-82 250.0 COG0548@1|root,COG0548@2|Bacteria,1TP0N@1239|Firmicutes,4HH91@91061|Bacilli,1ZF3H@1386|Bacillus 91061|Bacilli E Belongs to the acetylglutamate kinase family. ArgB subfamily argB GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R02649 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase k141_5846_1 666686.B1NLA3E_07915 6.93e-18 82.8 COG2046@1|root,COG2046@2|Bacteria,1TR4C@1239|Firmicutes,4HC20@91061|Bacilli,1ZCB4@1386|Bacillus 91061|Bacilli P Belongs to the sulfate adenylyltransferase family sat - 2.7.7.4 ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176,M00596 R00529,R04929 RC02809,RC02889 ko00000,ko00001,ko00002,ko01000 - - - ATP-sulfurylase,PUA_2 k141_5846_2 218284.CCDN010000001_gene1472 3.75e-137 398.0 COG0306@1|root,COG0306@2|Bacteria,1TQ3D@1239|Firmicutes,4HAPD@91061|Bacilli,1ZBFE@1386|Bacillus 91061|Bacilli P phosphate transporter cysP GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661 - ko:K16331 - - - - ko00000,ko02000 2.A.20.4 - - PHO4 k141_21048_1 441769.ABFU01000031_gene1724 1.62e-15 70.9 2CH7X@1|root,30CIB@2|Bacteria,1U9Y0@1239|Firmicutes,4IK5R@91061|Bacilli,1ZPNG@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_31593_1 1453501.JELR01000001_gene3120 3.63e-19 87.0 COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN3T@1236|Gammaproteobacteria,4666M@72275|Alteromonadaceae 1236|Gammaproteobacteria O Trypsin degP - - - - - - - - - - - PDZ_2,Trypsin_2 k141_31593_4 1453501.JELR01000001_gene3117 1.25e-43 148.0 COG1876@1|root,COG1876@2|Bacteria,1N2IC@1224|Proteobacteria,1S0DU@1236|Gammaproteobacteria,4679R@72275|Alteromonadaceae 1236|Gammaproteobacteria M D-alanyl-D-alanine carboxypeptidase vanY - - - - - - - - - - - VanY k141_29496_1 926560.KE387023_gene1179 5e-09 61.2 COG0719@1|root,COG0719@2|Bacteria,1WJ1E@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus O TIGRFAM FeS assembly protein SufD - - - ko:K09015 - - - - ko00000 - - - UPF0051 k141_29496_2 319795.Dgeo_0473 2.99e-56 188.0 COG0719@1|root,COG0719@2|Bacteria,1WIDC@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus O ABC-type transport system involved in Fe-S cluster assembly, permease component - - - ko:K09014 - - - - ko00000 - - - UPF0051 k141_4489_1 1260251.SPISAL_01535 1.83e-111 329.0 COG0320@1|root,COG0320@2|Bacteria,1MVRD@1224|Proteobacteria,1RMAT@1236|Gammaproteobacteria,1WXEN@135613|Chromatiales 135613|Chromatiales H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives lipA - 2.8.1.8 ko:K03644 ko00785,ko01100,map00785,map01100 - R07767,R07768 RC01978 ko00000,ko00001,ko01000 - - - LIAS_N,Radical_SAM k141_15149_1 1453501.JELR01000002_gene692 3.58e-54 176.0 COG0517@1|root,COG0517@2|Bacteria,1RJTX@1224|Proteobacteria,1S6K2@1236|Gammaproteobacteria,467TZ@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0517 FOG CBS domain - - - - - - - - - - - - CBS k141_30433_1 1131730.BAVI_02419 5.12e-65 211.0 COG1597@1|root,COG1597@2|Bacteria,1V7DZ@1239|Firmicutes,4HBUD@91061|Bacilli,1ZAUD@1386|Bacillus 91061|Bacilli I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase ytlR - - - - - - - - - - - DAGK_acc,DAGK_cat k141_30433_2 218284.CCDN010000008_gene4198 2.33e-38 143.0 COG1523@1|root,COG1523@2|Bacteria,1TP3M@1239|Firmicutes,4HBP5@91061|Bacilli,1ZC85@1386|Bacillus 91061|Bacilli G Belongs to the glycosyl hydrolase 13 family amyX - 3.2.1.41 ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 - R02111 - ko00000,ko00001,ko01000 - CBM48,GH13 - Alpha-amylase,CBM_48 k141_37690_1 435908.IDSA_08495 2.43e-61 202.0 COG1914@1|root,COG1914@2|Bacteria,1MW6X@1224|Proteobacteria,1RNA2@1236|Gammaproteobacteria,2QEZS@267893|Idiomarinaceae 1236|Gammaproteobacteria P Natural resistance-associated macrophage protein mntH - - - - - - - - - - - Nramp k141_3289_1 218284.CCDN010000002_gene2269 3.9e-85 258.0 COG0122@1|root,COG0122@2|Bacteria,1TQAF@1239|Firmicutes,4HBYM@91061|Bacilli,1ZCV5@1386|Bacillus 91061|Bacilli L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase yfjP GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003824,GO:0003905,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008725,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0032131,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0043733,GO:0043916,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.2.2.21 ko:K01247 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - HhH-GPD k141_3289_2 218284.CCDN010000002_gene2270 1.68e-32 123.0 COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,4HA6M@91061|Bacilli,1ZD4Q@1386|Bacillus 91061|Bacilli J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family rumA_1 - 2.1.1.190,2.1.1.35 ko:K00557,ko:K03215 - - - - ko00000,ko01000,ko03009,ko03016 - - - TRAM,tRNA_U5-meth_tr k141_29498_1 1116375.VEJY3_19011 2.9e-124 384.0 COG4192@1|root,COG4251@1|root,COG4192@2|Bacteria,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,1T1YP@1236|Gammaproteobacteria,1XSNQ@135623|Vibrionales 135623|Vibrionales T COG0642 Signal transduction histidine kinase torS - 2.7.13.3 ko:K07647 ko02020,map02020 M00455 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - 4HB_MCP_1,HATPase_c,HisKA,Hpt,Response_reg k141_24787_1 218284.CCDN010000002_gene2944 7.04e-147 422.0 COG4129@1|root,COG4129@2|Bacteria,1TPVH@1239|Firmicutes,4HAEG@91061|Bacilli,1ZCJA@1386|Bacillus 91061|Bacilli S Membrane ygaE - - - - - - - - - - - ArAE_1 k141_31594_1 749927.AMED_4294 1.74e-17 85.1 COG0458@1|root,COG0458@2|Bacteria,2GKXY@201174|Actinobacteria,4E1ZY@85010|Pseudonocardiales 201174|Actinobacteria EF PFAM Carbamoyl-phosphate synthase L chain, ATP binding domain - - - - - - - - - - - - ATP-grasp_4 k141_31594_2 1283300.ATXB01000002_gene3164 1.26e-80 258.0 COG2936@1|root,COG2936@2|Bacteria,1MVA8@1224|Proteobacteria,1RN7H@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Peptidase S15 cocE - - ko:K06978 - - - - ko00000 - - - PepX_C,Peptidase_S15 k141_4491_1 946483.Cenrod_1988 2.67e-20 96.3 COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,2VJ72@28216|Betaproteobacteria,4ABWU@80864|Comamonadaceae 28216|Betaproteobacteria T Adenylate cyclase cyaA - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - CHASE2,Guanylate_cyc k141_5848_1 1294265.JCM21738_585 1.3e-135 399.0 COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,1TQVT@1239|Firmicutes,4HB6K@91061|Bacilli,1ZBS9@1386|Bacillus 91061|Bacilli U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secD GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD_SecF,Sec_GG k141_26118_1 1294265.JCM21738_1702 2.14e-96 310.0 COG1277@1|root,COG1277@2|Bacteria,1TRJ8@1239|Firmicutes,4HA9I@91061|Bacilli,1ZCXM@1386|Bacillus 91061|Bacilli S ABC-type transport system involved in multi-copper enzyme maturation permease component - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - - k141_17496_2 1042377.AFPJ01000048_gene2685 1.13e-216 630.0 COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,1RSKR@1236|Gammaproteobacteria,46CIZ@72275|Alteromonadaceae 1236|Gammaproteobacteria KLT Lipopolysaccharide kinase (Kdo/WaaP) family - - 2.7.11.1 ko:K08884,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - Pkinase,TPR_16,TPR_19,TPR_2,TPR_8 k141_11853_4 1279017.AQYJ01000028_gene2153 3.7e-32 117.0 2EG5Q@1|root,339XK@2|Bacteria,1NGQ6@1224|Proteobacteria,1SHCX@1236|Gammaproteobacteria,46923@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF4168) - - - - - - - - - - - - DUF4168 k141_11853_7 929556.Solca_1036 1.74e-13 80.9 COG2885@1|root,COG2885@2|Bacteria,4NE8J@976|Bacteroidetes,1IPSE@117747|Sphingobacteriia 976|Bacteroidetes M Belongs to the ompA family - - - - - - - - - - - - OMP_b-brl,OmpA,TSP_3 k141_10525_1 1279017.AQYJ01000022_gene2715 6.02e-165 464.0 COG1235@1|root,COG1235@2|Bacteria,1R5N4@1224|Proteobacteria,1S2TG@1236|Gammaproteobacteria,466KS@72275|Alteromonadaceae 1236|Gammaproteobacteria S Beta-lactamase superfamily domain yycJ - - - - - - - - - - - Lactamase_B_2 k141_22562_2 335543.Sfum_0737 9.35e-19 82.0 COG0589@1|root,COG0589@2|Bacteria,1NDJW@1224|Proteobacteria,430KQ@68525|delta/epsilon subdivisions,2WVKY@28221|Deltaproteobacteria,2MRZ2@213462|Syntrophobacterales 28221|Deltaproteobacteria T Universal stress protein family - - - - - - - - - - - - Usp k141_5889_1 42565.FP66_01450 6.92e-110 320.0 COG1179@1|root,COG1179@2|Bacteria,1MWXR@1224|Proteobacteria,1RMT3@1236|Gammaproteobacteria,1XHB5@135619|Oceanospirillales 135619|Oceanospirillales H UBA THIF-type NAD FAD binding - - - ko:K22132 - - - - ko00000,ko03016 - - - ThiF k141_35603_1 1122185.N792_13210 4.76e-109 321.0 COG1209@1|root,COG1209@2|Bacteria,1MU0X@1224|Proteobacteria,1RMTR@1236|Gammaproteobacteria,1X399@135614|Xanthomonadales 135614|Xanthomonadales M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis rmlA - 2.7.7.24 ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 M00793 R02328 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase k141_35603_2 1163408.UU9_03118 2.25e-05 45.1 COG1898@1|root,COG1898@2|Bacteria,1R9YD@1224|Proteobacteria,1S245@1236|Gammaproteobacteria,1X327@135614|Xanthomonadales 135614|Xanthomonadales M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose rmlC - 5.1.3.13 ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R06514 RC01531 ko00000,ko00001,ko00002,ko01000 - - - dTDP_sugar_isom k141_1144_1 1294265.JCM21738_3334 1.16e-07 52.0 COG0001@1|root,COG0001@2|Bacteria,1TPNH@1239|Firmicutes,4HBDZ@91061|Bacilli,1ZB74@1386|Bacillus 91061|Bacilli H Glutamate-1-semialdehyde aminotransferase gsaB - 5.4.3.8 ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02272 RC00677 ko00000,ko00001,ko00002,ko01000,ko01007 - - iYO844.BSU08710 Aminotran_3 k141_1144_2 1294265.JCM21738_3335 1.79e-114 331.0 COG0067@1|root,COG0067@2|Bacteria,1UKBP@1239|Firmicutes,4ITH2@91061|Bacilli 91061|Bacilli E glutamate synthase - - - - - - - - - - - - GATase_2 k141_20117_1 1453501.JELR01000002_gene866 3.16e-182 521.0 COG0457@1|root,COG0457@2|Bacteria,1NAJI@1224|Proteobacteria 1224|Proteobacteria T ATPase activity - - - - - - - - - - - - DUF1570 k141_20117_2 203122.Sde_1703 1.25e-22 95.1 COG3507@1|root,COG3507@2|Bacteria,1QWZV@1224|Proteobacteria,1T31I@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Pectate lyase - - - - - - - - - - - - Pectate_lyase,RicinB_lectin_2 k141_21073_1 1453501.JELR01000002_gene1141 7.02e-74 234.0 COG0508@1|root,COG0508@2|Bacteria,1MVDC@1224|Proteobacteria,1RQ9Y@1236|Gammaproteobacteria,4657Y@72275|Alteromonadaceae 1236|Gammaproteobacteria C 2-oxoacid dehydrogenases acyltransferase (catalytic domain) pdhC - 2.3.1.12,2.3.1.168 ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 M00036,M00307 R00209,R02569,R02662,R03174,R04097,R10998 RC00004,RC02727,RC02742,RC02857,RC02870 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding k141_16446_1 218284.CCDN010000002_gene1988 1.94e-204 585.0 COG0046@1|root,COG0046@2|Bacteria,1TPAS@1239|Firmicutes,4HB3N@91061|Bacilli,1ZCN8@1386|Bacillus 91061|Bacilli F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL purL GO:0003674,GO:0003824,GO:0004642,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C k141_13018_1 1279017.AQYJ01000021_gene2802 3.62e-95 283.0 COG0593@1|root,COG0593@2|Bacteria,1MVW6@1224|Proteobacteria,1RPJP@1236|Gammaproteobacteria,46796@72275|Alteromonadaceae 1236|Gammaproteobacteria L Belongs to the DnaA family. HdA subfamily hda GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006275,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008156,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030174,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1901576,GO:2000104,GO:2000112,GO:2000113 - ko:K10763 - - - - ko00000,ko03032 - - - Bac_DnaA k141_13018_2 1279017.AQYJ01000021_gene2801 1.54e-123 363.0 COG3249@1|root,COG3249@2|Bacteria,1N0PD@1224|Proteobacteria,1S9C4@1236|Gammaproteobacteria,466SQ@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria VV2512 - - ko:K09938 - - - - ko00000 - - - DUF2066 k141_5890_2 218284.CCDN010000001_gene1018 2.73e-56 181.0 COG1028@1|root,COG1028@2|Bacteria,1TR5M@1239|Firmicutes,4HCD2@91061|Bacilli,1ZD11@1386|Bacillus 91061|Bacilli IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) gdh - 1.1.1.47 ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 - R01520,R01521 RC00066 ko00000,ko00001,ko01000 - - - adh_short_C2 k141_29525_1 1279017.AQYJ01000024_gene1011 3.63e-58 186.0 COG3017@1|root,COG3017@2|Bacteria,1N02T@1224|Proteobacteria,1S91E@1236|Gammaproteobacteria,468AP@72275|Alteromonadaceae 1236|Gammaproteobacteria M Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein lolB GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006807,GO:0008104,GO:0008150,GO:0008152,GO:0008289,GO:0009279,GO:0010876,GO:0016020,GO:0019538,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0033218,GO:0034613,GO:0042157,GO:0042277,GO:0043170,GO:0044238,GO:0044462,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051641,GO:0051668,GO:0070727,GO:0071704,GO:0071723,GO:0071944,GO:0072657,GO:1901564 - ko:K02494 - - - - ko00000 - - - LolB k141_29525_2 1279017.AQYJ01000024_gene1010 3.54e-123 361.0 COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,1RP23@1236|Gammaproteobacteria,464HJ@72275|Alteromonadaceae 1236|Gammaproteobacteria I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol ispE GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006629,GO:0006720,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050515,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576 2.7.1.148 ko:K00919 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05634 RC00002,RC01439 ko00000,ko00001,ko00002,ko01000 - - iEC55989_1330.EC55989_1304 GHMP_kinases_C,GHMP_kinases_N k141_2055_4 1433126.BN938_1696 8.85e-07 49.3 COG1813@1|root,COG1813@2|Bacteria,4PKWR@976|Bacteroidetes,2G13A@200643|Bacteroidia 976|Bacteroidetes K Cro/C1-type HTH DNA-binding domain - - 3.4.21.88 ko:K01356 - M00729 - - ko00000,ko00002,ko01000,ko01002,ko03400 - - - HTH_26,HTH_3,Peptidase_S24 k141_24817_1 218284.CCDN010000002_gene2882 4.63e-72 223.0 COG3764@1|root,COG3764@2|Bacteria,1V79B@1239|Firmicutes,4HJ8C@91061|Bacilli,1ZHDM@1386|Bacillus 91061|Bacilli M Sortase family - - - - - - - - - - - - Sortase k141_17853_1 1294265.JCM21738_4164 2.33e-185 538.0 COG0085@1|root,COG0085@2|Bacteria,1TP96@1239|Firmicutes,4H9PK@91061|Bacilli,1ZBPC@1386|Bacillus 91061|Bacilli K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoB GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 k141_17853_2 1294265.JCM21738_4165 4.7e-134 411.0 COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,4HA24@91061|Bacilli,1ZDK0@1386|Bacillus 91061|Bacilli K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoC GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 k141_3601_1 218284.CCDN010000002_gene2371 2.38e-117 345.0 COG0477@1|root,COG2814@2|Bacteria,1TQKU@1239|Firmicutes,4HA5Q@91061|Bacilli,1ZCSQ@1386|Bacillus 91061|Bacilli EGP COG0477 Permeases of the major facilitator superfamily yybF - - ko:K08224 - - - - ko00000,ko02000 2.A.1.36 - - MFS_1,Sugar_tr k141_7151_1 218284.CCDN010000002_gene2859 6.21e-86 260.0 2DB9X@1|root,2Z7ZS@2|Bacteria,1VS9F@1239|Firmicutes,4HTUJ@91061|Bacilli,1ZC1U@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3445) - - 1.14.13.238 ko:K22342 - - - - ko00000,ko01000 - - - DUF3445 k141_7151_2 218284.CCDN010000002_gene2860 3.98e-46 153.0 2DWNN@1|root,3417F@2|Bacteria,1W28F@1239|Firmicutes,4I1N7@91061|Bacilli,1ZHY2@1386|Bacillus 91061|Bacilli - - - - 1.14.13.238 ko:K22344 - - - - ko00000,ko01000 - - - - k141_34504_1 1294265.JCM21738_3772 5.54e-146 416.0 COG0476@1|root,COG0476@2|Bacteria,1TQ3U@1239|Firmicutes,4HBGP@91061|Bacilli,1ZBR4@1386|Bacillus 91061|Bacilli H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 - - 2.7.7.73,2.7.7.80 ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07459 RC00043 ko00000,ko00001,ko01000 - - - ThiF k141_30932_1 218284.CCDN010000001_gene1399 1.39e-112 339.0 COG1966@1|root,COG1966@2|Bacteria,1TQN8@1239|Firmicutes,4H9SU@91061|Bacilli,1ZC6K@1386|Bacillus 91061|Bacilli T Carbon starvation protein cstA GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007154,GO:0008150,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031667,GO:0031668,GO:0031669,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:0071944 - ko:K06200 - - - - ko00000 - - - CstA,CstA_5TM k141_21434_1 1453501.JELR01000002_gene825 1.08e-71 244.0 COG3866@1|root,COG3866@2|Bacteria,1QPFF@1224|Proteobacteria,1RQEM@1236|Gammaproteobacteria,465CX@72275|Alteromonadaceae 1236|Gammaproteobacteria G Amb_all pel1C - - - - - - - - - - - CBM_35,CBM_5_12_2,CBM_6,Pec_lyase_C,RicinB_lectin_2 k141_35694_1 218284.CCDN010000002_gene2763 4.84e-142 406.0 COG1041@1|root,COG1041@2|Bacteria,1TRH9@1239|Firmicutes,4HCHR@91061|Bacilli,1ZBCC@1386|Bacillus 91061|Bacilli L Putative RNA methylase family UPF0020 rumA - - - - - - - - - - - UPF0020 k141_15495_1 501479.ACNW01000091_gene2239 4.41e-20 86.7 COG3741@1|root,COG3741@2|Bacteria,1MY4D@1224|Proteobacteria,2TUPZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria E N-formylglutamate amidohydrolase MA20_06380 - 3.5.1.68 ko:K01458 ko00340,ko00630,map00340,map00630 - R00525 RC00165,RC00323 ko00000,ko00001,ko01000 - - - FGase k141_22610_1 1294265.JCM21738_476 2.05e-20 83.6 COG1765@1|root,COG1765@2|Bacteria,1V78R@1239|Firmicutes,4HMM3@91061|Bacilli,1ZH2T@1386|Bacillus 91061|Bacilli O OsmC-like protein - - - - - - - - - - - - OsmC k141_22610_2 666686.B1NLA3E_02335 1.18e-54 181.0 COG0477@1|root,COG2814@2|Bacteria,1TPW3@1239|Firmicutes,4H9R6@91061|Bacilli,1ZBYT@1386|Bacillus 91061|Bacilli EGP Major facilitator superfamily yfkF - - - - - - - - - - - MFS_1,MFS_1_like,Sugar_tr k141_8357_1 1116375.VEJY3_05370 0.0 1292.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1XSPS@135623|Vibrionales 135623|Vibrionales U COG0841 Cation multidrug efflux pump acrB - - ko:K18138 ko01501,ko01503,map01501,map01503 M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2 - - ACR_tran k141_8357_2 1116375.VEJY3_05365 3.35e-225 626.0 COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,1RPI1@1236|Gammaproteobacteria,1XTHC@135623|Vibrionales 135623|Vibrionales M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family acrA - - ko:K03585 ko01501,ko01503,map01501,map01503 M00646,M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,8.A.1.6 - - Biotin_lipoyl_2,HlyD,HlyD_D23 k141_8357_3 1116375.VEJY3_05360 1.45e-161 461.0 COG3135@1|root,COG3135@2|Bacteria,1MUS1@1224|Proteobacteria,1RMD5@1236|Gammaproteobacteria,1XUP6@135623|Vibrionales 135623|Vibrionales Q Benzoate membrane transport protein - - - ko:K05782 - - - - ko00000,ko02000 2.A.46.1 - - BenE k141_26189_1 218284.CCDN010000007_gene3924 1.03e-152 432.0 COG1131@1|root,COG1131@2|Bacteria,1TQKM@1239|Firmicutes,4HBUK@91061|Bacilli,1ZDAX@1386|Bacillus 91061|Bacilli V COG1131 ABC-type multidrug transport system, ATPase component ybhF_2 - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_5979_1 218284.CCDN010000011_gene4423 8.07e-108 333.0 COG1305@1|root,COG1305@2|Bacteria,1TP8K@1239|Firmicutes,4HB2E@91061|Bacilli,1ZBUN@1386|Bacillus 91061|Bacilli E COG1305 Transglutaminase-like enzymes yebA - - - - - - - - - - - DUF4129,Transglut_core k141_34505_1 218284.CCDN010000002_gene2036 1.32e-115 334.0 COG2049@1|root,COG2049@2|Bacteria,1TTBZ@1239|Firmicutes,4HHJJ@91061|Bacilli,1ZDVS@1386|Bacillus 91061|Bacilli E Allophanate hydrolase subunit 1 kipI - - ko:K06351 - - - - ko00000 - - - CT_C_D k141_23799_1 1279017.AQYJ01000028_gene2074 7.81e-90 294.0 COG1729@1|root,COG1729@2|Bacteria,1MX82@1224|Proteobacteria,1T32S@1236|Gammaproteobacteria,465Q0@72275|Alteromonadaceae 1236|Gammaproteobacteria O protein conserved in bacteria - - - - - - - - - - - - TPR_16,TPR_6,TPR_8,YfiO k141_23799_2 1279017.AQYJ01000028_gene2075 8.22e-158 477.0 COG0457@1|root,COG0457@2|Bacteria,1MXSS@1224|Proteobacteria,1S157@1236|Gammaproteobacteria,467PR@72275|Alteromonadaceae 1236|Gammaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16,TPR_6 k141_23799_4 1279017.AQYJ01000028_gene2077 7.44e-162 462.0 COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,1RNMZ@1236|Gammaproteobacteria,4658H@72275|Alteromonadaceae 1236|Gammaproteobacteria H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein - - 2.7.1.180 ko:K03734 - - - - ko00000,ko01000 - - - ApbE k141_21435_1 1117379.BABA_07636 1.12e-87 282.0 COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,4H9XC@91061|Bacilli,1ZB9E@1386|Bacillus 91061|Bacilli J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain alaS GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DHHA1,tRNA-synt_2c,tRNA_SAD k141_33316_2 218284.CCDN010000001_gene627 8.74e-66 202.0 COG2891@1|root,COG2891@2|Bacteria,1VEN7@1239|Firmicutes,4HNWW@91061|Bacilli,1ZGID@1386|Bacillus 91061|Bacilli M shape-determining protein mreD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03571 - - - - ko00000,ko03036 9.B.157.1 - - MreD k141_30933_1 675812.VHA_001676 8.41e-07 50.8 COG3019@1|root,COG3019@2|Bacteria,1MZ9V@1224|Proteobacteria,1S9CQ@1236|Gammaproteobacteria,1XX3N@135623|Vibrionales 135623|Vibrionales S Protein of unknown function, DUF copG - - - - - - - - - - - DUF411 k141_30933_2 1042377.AFPJ01000007_gene1792 2.97e-47 160.0 COG4301@1|root,COG4301@2|Bacteria,1MUCG@1224|Proteobacteria,1RR44@1236|Gammaproteobacteria,466C6@72275|Alteromonadaceae 1236|Gammaproteobacteria S Histidine-specific methyltransferase, SAM-dependent egtD - - - - - - - - - - - Methyltransf_33 k141_10715_1 866895.HBHAL_1008 2.96e-94 298.0 COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,4HAHY@91061|Bacilli,3NDCN@45667|Halobacillus 91061|Bacilli L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrA - 5.99.1.3 ko:K02469 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseA_C,DNA_topoisoIV k141_16662_2 218284.CCDN010000002_gene2071 1.93e-85 253.0 COG1633@1|root,COG1633@2|Bacteria,1V4ZN@1239|Firmicutes,4HH0Q@91061|Bacilli,1ZGWB@1386|Bacillus 91061|Bacilli S Ferritin-like domain - - 1.16.3.1 ko:K03594 ko00860,map00860 - R00078 RC02758 ko00000,ko00001,ko01000 - - - Ferritin k141_26190_1 290398.Csal_0103 3.51e-97 295.0 COG0642@1|root,COG0642@2|Bacteria,1QTVA@1224|Proteobacteria,1T1IE@1236|Gammaproteobacteria,1XRTM@135619|Oceanospirillales 135619|Oceanospirillales T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - 2.7.13.3 ko:K07644 ko02020,map02020 M00452,M00745 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 - - - HATPase_c,HisKA k141_28571_1 643473.KB235930_gene2152 0.000103 47.0 COG2267@1|root,COG2267@2|Bacteria,1G14K@1117|Cyanobacteria,1HJJZ@1161|Nostocales 1117|Cyanobacteria I Alpha beta hydrolase - - - - - - - - - - - - Abhydrolase_1 k141_11908_2 981383.AEWH01000031_gene601 3.33e-69 210.0 COG0346@1|root,COG0346@2|Bacteria,1V93D@1239|Firmicutes,4HI94@91061|Bacilli 91061|Bacilli E lactoylglutathione lyase activity - - - - - - - - - - - - Glyoxalase k141_13112_1 458233.MCCL_0913 1.56e-35 132.0 COG3935@1|root,COG3935@2|Bacteria,1V99B@1239|Firmicutes,4HK5M@91061|Bacilli,4GZJB@90964|Staphylococcaceae 91061|Bacilli L Replication initiation and membrane attachment - - - - - - - - - - - - DnaB_2 k141_24976_1 1198114.AciX9_1856 0.000139 46.2 COG2244@1|root,COG2244@2|Bacteria 2|Bacteria S polysaccharide biosynthetic process - - - ko:K03328 - - - - ko00000 2.A.66.2 - - Polysacc_synt_3,Polysacc_synt_C k141_24976_2 1166018.FAES_3183 7.98e-26 115.0 COG1835@1|root,COG1835@2|Bacteria,4NPI2@976|Bacteroidetes,47JPN@768503|Cytophagia 976|Bacteroidetes I Acyltransferase family - - - - - - - - - - - - Acyl_transf_3 k141_24976_3 1087481.AGFX01000046_gene2041 7.24e-21 104.0 COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,4HAHU@91061|Bacilli,26Q93@186822|Paenibacillaceae 91061|Bacilli Q Non-ribosomal peptide synthetase modules and related proteins - - - - - - - - - - - - AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase k141_29739_1 1285586.H131_21892 8.86e-56 188.0 COG0740@1|root,COG0740@2|Bacteria,1TR2H@1239|Firmicutes,4HBZH@91061|Bacilli,3IYGP@400634|Lysinibacillus 91061|Bacilli OU Belongs to the peptidase S14 family clpP - 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 - - - ko00000,ko00001,ko01000,ko01002 - - - CLP_protease k141_21436_1 1385514.N782_00375 5.27e-39 144.0 COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,4HADT@91061|Bacilli,2YBFQ@289201|Pontibacillus 91061|Bacilli KT Sigma-54 interaction domain - - - - - - - - - - - - HTH_8,PAS,PAS_4,PAS_9,Sigma54_activat k141_7152_1 218284.CCDN010000001_gene1460 3.59e-97 297.0 COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HA2G@91061|Bacilli,1ZC9Y@1386|Bacillus 91061|Bacilli IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding,AMP-binding_C k141_7152_2 218284.CCDN010000001_gene1461 2.99e-86 257.0 COG1309@1|root,COG1309@2|Bacteria,1V3QD@1239|Firmicutes,4HHEF@91061|Bacilli,1ZBBX@1386|Bacillus 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - TetR_C_4,TetR_N k141_8359_1 706587.Desti_2864 2.27e-10 62.4 COG0842@1|root,COG0842@2|Bacteria,1MVUG@1224|Proteobacteria,42US7@68525|delta/epsilon subdivisions,2X9TS@28221|Deltaproteobacteria,2MRK3@213462|Syntrophobacterales 28221|Deltaproteobacteria V ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane k141_8359_2 1297742.A176_04862 1.39e-16 79.7 COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,42RT8@68525|delta/epsilon subdivisions,2WNE9@28221|Deltaproteobacteria,2Z0NP@29|Myxococcales 28221|Deltaproteobacteria V ABC transporter - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 k141_17855_1 1169144.KB910958_gene3926 4.45e-66 210.0 COG1385@1|root,COG1385@2|Bacteria,1V1CT@1239|Firmicutes,4HH8P@91061|Bacilli,1ZAV7@1386|Bacillus 91061|Bacilli J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit rsmE GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.193 ko:K09761 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_RNA k141_17855_2 218284.CCDN010000001_gene736 2.03e-192 537.0 COG2264@1|root,COG2264@2|Bacteria,1TPKI@1239|Firmicutes,4HAMF@91061|Bacilli,1ZB7J@1386|Bacillus 91061|Bacilli J Methylates ribosomal protein L11 prmA - - ko:K02687 - - - - ko00000,ko01000,ko03009 - - - PrmA k141_31_1 1121936.AUHI01000009_gene249 2.03e-106 326.0 COG4325@1|root,COG4325@2|Bacteria,1TSK8@1239|Firmicutes,4HCYY@91061|Bacilli 91061|Bacilli S Predicted membrane protein (DUF2254) - - - - - - - - - - - - DUF2254 k141_20229_1 218284.CCDN010000002_gene2123 3.29e-101 306.0 COG0065@1|root,COG0065@2|Bacteria,1TPE5@1239|Firmicutes,4HAWA@91061|Bacilli,1ZCF1@1386|Bacillus 91061|Bacilli E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate leuC - 4.2.1.33,4.2.1.35 ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170 RC00497,RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS10700 Aconitase k141_4791_1 218284.CCDN010000006_gene3572 2.96e-148 434.0 COG4264@1|root,COG4264@2|Bacteria,1TSC3@1239|Firmicutes,4HDUE@91061|Bacilli,1ZQIZ@1386|Bacillus 91061|Bacilli Q IucA / IucC family - - - - - - - - - - - - FhuF,IucA_IucC k141_30934_1 1294265.JCM21738_596 3.87e-173 487.0 COG2255@1|root,COG2255@2|Bacteria,1TR47@1239|Firmicutes,4HBMW@91061|Bacilli,1ZC5A@1386|Bacillus 91061|Bacilli L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing ruvB - 3.6.4.12 ko:K03551 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvB_C,RuvB_N k141_28572_1 1499680.CCFE01000032_gene3884 1.79e-63 196.0 COG3877@1|root,COG3877@2|Bacteria,1VAFG@1239|Firmicutes,4HJ4J@91061|Bacilli,1ZGM8@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2089) - - - - - - - - - - - - DUF2089 k141_28572_2 545693.BMQ_3691 4.02e-52 167.0 2EA9N@1|root,334E2@2|Bacteria,1VEP2@1239|Firmicutes,4HJ3E@91061|Bacilli,1ZG6V@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_8360_1 1280947.HY30_09755 7.9e-30 121.0 COG3507@1|root,COG3507@2|Bacteria,1NNX4@1224|Proteobacteria,2U06C@28211|Alphaproteobacteria,43ZEC@69657|Hyphomonadaceae 28211|Alphaproteobacteria G Belongs to the glycosyl hydrolase 43 family - - 3.2.1.37,3.2.1.55 ko:K01198,ko:K01209 ko00520,ko01100,map00520,map01100 - R01433,R01762 RC00467 ko00000,ko00001,ko01000 - GH43,GH51 - Glyco_hydro_43 k141_17856_1 218284.CCDN010000006_gene3562 1.82e-78 245.0 COG0477@1|root,COG2814@2|Bacteria,1TQHD@1239|Firmicutes,4HBCZ@91061|Bacilli,1ZAUW@1386|Bacillus 91061|Bacilli EGP COG0477 Permeases of the major facilitator superfamily ywoG GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - - - - - - - - - - MFS_1,MFS_1_like,MFS_2,Sugar_tr k141_35696_1 218284.CCDN010000001_gene122 4.17e-60 196.0 COG0628@1|root,COG0628@2|Bacteria,1TSI9@1239|Firmicutes,4HB3Q@91061|Bacilli,1ZD70@1386|Bacillus 91061|Bacilli S AI-2E family transporter - - - - - - - - - - - - AI-2E_transport k141_15498_1 1453501.JELR01000005_gene1566 2.19e-112 345.0 COG4773@1|root,COG4773@2|Bacteria,1QTXJ@1224|Proteobacteria,1T2BS@1236|Gammaproteobacteria,46D8F@72275|Alteromonadaceae 1236|Gammaproteobacteria P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec k141_5980_1 218284.CCDN010000008_gene4169 3.14e-213 598.0 COG1866@1|root,COG1866@2|Bacteria,1TPQV@1239|Firmicutes,4HAKG@91061|Bacilli,1ZCVN@1386|Bacillus 91061|Bacilli C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA pckA GO:0000166,GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0017076,GO:0019318,GO:0019319,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576 4.1.1.49 ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 M00003,M00170 R00341 RC00002,RC02741 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS09060,iYO844.BSU30560 PEPCK_ATP k141_14293_2 1042377.AFPJ01000004_gene382 3.29e-15 74.3 COG4221@1|root,COG4221@2|Bacteria,1R83E@1224|Proteobacteria,1T1UP@1236|Gammaproteobacteria,46DB1@72275|Alteromonadaceae 1236|Gammaproteobacteria S KR domain - - - - - - - - - - - - adh_short k141_32_1 1294265.JCM21738_2558 9.09e-129 378.0 COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TSKR@1239|Firmicutes,4H9R5@91061|Bacilli,1ZDUE@1386|Bacillus 91061|Bacilli T COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain - - - ko:K07720 ko02020,map02020 M00519 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_18,HTH_AraC,Response_reg k141_16665_1 1415756.JQMY01000001_gene2869 7.55e-14 64.7 COG4890@1|root,COG4890@2|Bacteria,1NGDQ@1224|Proteobacteria,2UJD5@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Cyd operon protein YbgT - - 1.10.3.14 ko:K00424 ko00190,ko02020,map00190,map02020 M00153 - - ko00000,ko00001,ko01000 3.D.4.3 - - YbgT_YccB k141_16665_2 314265.R2601_26756 2.86e-45 156.0 COG1294@1|root,COG1294@2|Bacteria,1MURP@1224|Proteobacteria,2TU3I@28211|Alphaproteobacteria 28211|Alphaproteobacteria C oxidase subunit cydB - 1.10.3.14 ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - Cyt_bd_oxida_II k141_8362_1 218284.CCDN010000005_gene3197 1.12e-107 330.0 COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,4H9T9@91061|Bacilli,1ZBH0@1386|Bacillus 91061|Bacilli S YhgE Pip N-terminal domain protein yhgE - - ko:K01421 - - - - ko00000 - - - ABC2_membrane_3,DUF3533 k141_23803_1 935836.JAEL01000107_gene2266 4.74e-54 182.0 COG1292@1|root,COG1292@2|Bacteria,1TRS6@1239|Firmicutes,4HA7U@91061|Bacilli,1ZBRN@1386|Bacillus 91061|Bacilli M Belongs to the BCCT transporter (TC 2.A.15) family - - - ko:K05020 - - - - ko00000,ko02000 2.A.15.1.1,2.A.15.1.11 - - BCCT k141_36875_1 1121923.GPUN_0346 1.23e-26 112.0 COG4206@1|root,COG4206@2|Bacteria,1QUGQ@1224|Proteobacteria,1T241@1236|Gammaproteobacteria,464Q2@72275|Alteromonadaceae 1236|Gammaproteobacteria H TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_60_1 218284.CCDN010000004_gene3124 1.78e-67 207.0 COG0589@1|root,COG0589@2|Bacteria,1VH3X@1239|Firmicutes,4HNXN@91061|Bacilli,1ZCYJ@1386|Bacillus 91061|Bacilli T Universal stress protein nhaX - - - - - - - - - - - Usp k141_10732_1 218284.CCDN010000001_gene1801 9.85e-143 407.0 COG0464@1|root,COG0464@2|Bacteria,1TPQZ@1239|Firmicutes,4HCQK@91061|Bacilli,1ZBII@1386|Bacillus 91061|Bacilli O stage V sporulation protein K spoVK - - ko:K06413 - - - - ko00000 - - - AAA k141_36890_1 911045.PSE_2035 9.24e-44 154.0 COG0604@1|root,COG0604@2|Bacteria,1MWRK@1224|Proteobacteria,2TQMF@28211|Alphaproteobacteria 28211|Alphaproteobacteria C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - 1.6.5.5 ko:K00344 - - - - ko00000,ko01000 - - - ADH_N,ADH_zinc_N k141_14321_1 1116375.VEJY3_03410 1.01e-237 658.0 COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,1RNQ8@1236|Gammaproteobacteria,1XTUS@135623|Vibrionales 135623|Vibrionales H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) hemA GO:0003674,GO:0003824,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0008883,GO:0009058,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.2.1.70 ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R04109 RC00055,RC00149 ko00000,ko00001,ko00002,ko01000 - - - GlutR_N,GlutR_dimer,Shikimate_DH k141_14321_2 1116375.VEJY3_03405 1.38e-136 388.0 COG3017@1|root,COG3017@2|Bacteria,1N02T@1224|Proteobacteria,1S91E@1236|Gammaproteobacteria,1XX2S@135623|Vibrionales 135623|Vibrionales M Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein lolB GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - ko:K02494 - - - - ko00000 - - - LolB k141_14321_3 1219080.VEZ01S_32_00040 2.54e-23 95.9 COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,1RP23@1236|Gammaproteobacteria,1XUCF@135623|Vibrionales 135623|Vibrionales F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol ispE GO:0003674,GO:0003824,GO:0006629,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050515,GO:0071704,GO:1901576 2.7.1.148 ko:K00919 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05634 RC00002,RC01439 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N k141_2426_1 314265.R2601_02333 7.47e-105 322.0 COG4774@1|root,COG4774@2|Bacteria,1MV0X@1224|Proteobacteria,2TVX5@28211|Alphaproteobacteria 28211|Alphaproteobacteria P TonB-dependent siderophore receptor fhuA - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_29748_1 218284.CCDN010000001_gene1111 1.89e-84 257.0 COG0142@1|root,COG0142@2|Bacteria,1TR0U@1239|Firmicutes,4H9RH@91061|Bacilli,1ZAZ7@1386|Bacillus 91061|Bacilli H Belongs to the FPP GGPP synthase family hepT GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.30,2.5.1.83 ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 - R09245,R09247 RC00279 ko00000,ko00001,ko01000,ko01006 - - - polyprenyl_synt k141_7158_1 656519.Halsa_1674 2.2e-12 73.6 COG1480@1|root,COG1480@2|Bacteria,1TR1A@1239|Firmicutes,249W0@186801|Clostridia,3WA9K@53433|Halanaerobiales 186801|Clostridia S 7TM receptor with intracellular HD hydrolase - - - ko:K07037 - - - - ko00000 - - - 7TM-7TMR_HD,7TMR-HDED,HD k141_11924_1 1174504.AJTN02000219_gene1067 3.34e-52 175.0 299D6@1|root,2ZWG2@2|Bacteria,1V564@1239|Firmicutes,4HI66@91061|Bacilli,1ZQ61@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2785) - - - - - - - - - - - - DUF2785 k141_21449_1 1294265.JCM21738_3348 1.91e-108 328.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,1ZAY7@1386|Bacillus 91061|Bacilli V ABC transporter ygaD GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702 - ko:K11085 ko02010,map02010 - - - ko00000,ko00001,ko01000,ko02000 3.A.1.106 - - ABC_membrane,ABC_tran k141_13148_1 218284.CCDN010000001_gene778 9.28e-53 169.0 COG4709@1|root,COG4709@2|Bacteria,1VEVX@1239|Firmicutes,4HP5D@91061|Bacilli,1ZIJI@1386|Bacillus 91061|Bacilli S membrane yqfX - - - - - - - - - - - - k141_61_1 218284.CCDN010000007_gene3860 8.72e-130 405.0 COG1674@1|root,COG1674@2|Bacteria,1TRA4@1239|Firmicutes,4H9QM@91061|Bacilli,1ZDSN@1386|Bacillus 91061|Bacilli D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins essC - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FHA,FtsK_SpoIIIE,FtsK_SpoIIIE_N k141_20248_1 218284.CCDN010000001_gene973 4.05e-101 293.0 COG1438@1|root,COG1438@2|Bacteria,1V1R7@1239|Firmicutes,4HFY8@91061|Bacilli,1ZFJ8@1386|Bacillus 91061|Bacilli K Regulates arginine biosynthesis genes argR GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006355,GO:0006520,GO:0006525,GO:0006807,GO:0008150,GO:0008152,GO:0009064,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031326,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1901564,GO:1901605,GO:1903506,GO:2000112,GO:2001141 - ko:K03402 - - - - ko00000,ko03000 - - - Arg_repressor,Arg_repressor_C k141_2427_1 1397696.KK211189_gene726 1.34e-47 158.0 COG1670@1|root,COG1670@2|Bacteria,1V449@1239|Firmicutes,4HJA0@91061|Bacilli 91061|Bacilli J Acetyltransferase (GNAT) domain - - 2.3.1.128 ko:K03789 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_1,Acetyltransf_10,Acetyltransf_3 k141_2427_2 218284.CCDN010000001_gene1729 2.47e-35 123.0 COG0454@1|root,COG0456@2|Bacteria,1V85Q@1239|Firmicutes,4IPX8@91061|Bacilli,1ZHKR@1386|Bacillus 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10 k141_9543_2 218284.CCDN010000008_gene4118 5.7e-128 365.0 28K22@1|root,2Z9RG@2|Bacteria,1UIKP@1239|Firmicutes,4HESR@91061|Bacilli,1ZS77@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF4396) - - - - - - - - - - - - DUF4396 k141_27372_1 1294265.JCM21738_3318 8.11e-59 197.0 COG0751@1|root,COG0751@2|Bacteria,1TNZ7@1239|Firmicutes,4H9NT@91061|Bacilli,1ZDF3@1386|Bacillus 91061|Bacilli J Glycyl-tRNA synthetase beta subunit glyS - 6.1.1.14 ko:K01879 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_1,tRNA_synt_2f k141_22640_1 861299.J421_3345 2.14e-73 234.0 COG3185@1|root,COG3185@2|Bacteria,1ZT5D@142182|Gemmatimonadetes 142182|Gemmatimonadetes E Acyclic terpene utilisation family protein AtuA - - - - - - - - - - - - AtuA k141_10733_2 171693.BN988_01905 3.79e-11 63.5 COG3181@1|root,COG3181@2|Bacteria,1V0HH@1239|Firmicutes,4HBWA@91061|Bacilli,23JU6@182709|Oceanobacillus 91061|Bacilli S Tripartite tricarboxylate transporter family receptor - - - ko:K07795 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.80.1 - - TctC k141_11925_1 1444309.JAQG01000012_gene2061 1.14e-63 214.0 COG0209@1|root,COG0209@2|Bacteria,1TT3U@1239|Firmicutes,4HFF1@91061|Bacilli,26R3N@186822|Paenibacillaceae 91061|Bacilli F Ribonucleotide reductase, barrel domain - - - - - - - - - - - - Ribonuc_red_lgC k141_3632_1 1453501.JELR01000002_gene945 4.41e-217 620.0 COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,1RN3Z@1236|Gammaproteobacteria,465HK@72275|Alteromonadaceae 1236|Gammaproteobacteria U COG4796 Type II secretory pathway, component HofQ pilQ GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0015976,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 - ko:K02507,ko:K02666 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - AMIN,STN,Secretin,Secretin_N k141_21452_1 426114.THI_1165 6.4e-06 47.0 COG3046@1|root,COG3046@2|Bacteria,1MUHX@1224|Proteobacteria,2VHTR@28216|Betaproteobacteria,1KJNW@119065|unclassified Burkholderiales 28216|Betaproteobacteria S deoxyribodipyrimidine photolyase-related protein - - - ko:K06876 - - - - ko00000 - - - DPRP k141_21452_2 398720.MED217_14785 4.73e-61 203.0 COG3046@1|root,COG3046@2|Bacteria,4NECD@976|Bacteroidetes,1HY91@117743|Flavobacteriia,2XI83@283735|Leeuwenhoekiella 976|Bacteroidetes S Deoxyribodipyrimidine photo-lyase-related protein - - - ko:K06876 - - - - ko00000 - - - DPRP k141_13150_1 1294265.JCM21738_2396 4.97e-97 290.0 COG2866@1|root,COG2866@2|Bacteria,1UR6S@1239|Firmicutes,4HAPV@91061|Bacilli,1ZDU8@1386|Bacillus 91061|Bacilli E Zn_pept - - - ko:K06987 - - - - ko00000 - - - Peptidase_M14 k141_31186_1 218284.CCDN010000006_gene3577 7.34e-112 333.0 COG0160@1|root,COG0160@2|Bacteria,1TRUG@1239|Firmicutes,4HBUU@91061|Bacilli,1ZCQV@1386|Bacillus 91061|Bacilli E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - 2.6.1.76 ko:K00836 ko00260,ko01100,ko01120,ko01210,ko01230,map00260,map01100,map01120,map01210,map01230 M00033 R06977 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 k141_25200_1 1279017.AQYJ01000028_gene2040 1.19e-20 90.1 2DBVC@1|root,2ZBAF@2|Bacteria,1PT3T@1224|Proteobacteria,1RZJK@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Psort location CytoplasmicMembrane, score 9.46 - - - - - - - - - - - - - k141_25200_2 1122179.KB890420_gene2473 1.14e-39 142.0 COG2755@1|root,COG2755@2|Bacteria 2|Bacteria E lipolytic protein G-D-S-L family - - 3.1.1.5 ko:K10804 ko01040,map01040 - - - ko00000,ko00001,ko01000,ko01004 - - - SASA k141_9691_1 106370.Francci3_2337 2.16e-09 61.2 COG1835@1|root,COG1835@2|Bacteria,2GS8J@201174|Actinobacteria,4EV68@85013|Frankiales 201174|Actinobacteria I PFAM acyltransferase 3 - - - - - - - - - - - - Acyl_transf_3 k141_9691_2 1279017.AQYJ01000028_gene2218 0.0 1172.0 COG0187@1|root,COG0187@2|Bacteria,1MVH1@1224|Proteobacteria,1RMCI@1236|Gammaproteobacteria,464P4@72275|Alteromonadaceae 1236|Gammaproteobacteria L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parE - - ko:K02622 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim k141_9691_3 1042377.AFPJ01000024_gene757 1.32e-81 249.0 COG3150@1|root,COG3150@2|Bacteria,1MVJF@1224|Proteobacteria,1S5WF@1236|Gammaproteobacteria,4674V@72275|Alteromonadaceae 1236|Gammaproteobacteria S esterase yqiA GO:0003674,GO:0003824,GO:0016787,GO:0016788 - ko:K07000 - - - - ko00000 - - - UPF0227 k141_9691_5 1279017.AQYJ01000028_gene2215 2.01e-136 392.0 COG1409@1|root,COG1409@2|Bacteria,1MWKX@1224|Proteobacteria,1RPA7@1236|Gammaproteobacteria,466SM@72275|Alteromonadaceae 1236|Gammaproteobacteria S Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes cpdA GO:0003674,GO:0003824,GO:0004112,GO:0004114,GO:0004115,GO:0005488,GO:0005506,GO:0008081,GO:0008150,GO:0008198,GO:0009987,GO:0016043,GO:0016787,GO:0016788,GO:0042545,GO:0042578,GO:0043167,GO:0043169,GO:0045229,GO:0046872,GO:0046914,GO:0071554,GO:0071555,GO:0071840 3.1.4.53 ko:K03651 ko00230,ko02025,map00230,map02025 - R00191 RC00296 ko00000,ko00001,ko01000 - - - Metallophos k141_9691_6 1042377.AFPJ01000024_gene760 5.82e-51 169.0 COG3151@1|root,COG3151@2|Bacteria,1RA4E@1224|Proteobacteria,1S55I@1236|Gammaproteobacteria,468KM@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria yqiB - - ko:K09920 - - - - ko00000 - - - DUF1249 k141_9691_7 1453501.JELR01000002_gene611 4.32e-27 105.0 COG0494@1|root,COG0494@2|Bacteria,1RDMW@1224|Proteobacteria,1RPZV@1236|Gammaproteobacteria,4670F@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes nudF GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019144,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0047631,GO:0050896 3.6.1.13 ko:K01515 ko00230,map00230 - R01054 RC00002 ko00000,ko00001,ko01000 - - iECP_1309.ECP_3126 NUDIX k141_16882_1 1453501.JELR01000005_gene1590 6.95e-154 478.0 COG1520@1|root,COG2133@1|root,COG1520@2|Bacteria,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,1RNGN@1236|Gammaproteobacteria,465UX@72275|Alteromonadaceae 1236|Gammaproteobacteria G Glucose / Sorbosone dehydrogenase - - - - - - - - - - - - Big_2,CBM26,Cytochrome_CBB3,GSDH,PSCyt3,PSD2,PSD3,PSD4,PSD5 k141_35868_1 218284.CCDN010000007_gene3913 5.26e-17 80.9 COG2133@1|root,COG2133@2|Bacteria,1TR38@1239|Firmicutes,4HBME@91061|Bacilli,1ZC94@1386|Bacillus 91061|Bacilli G COG2133 Glucose sorbosone dehydrogenases - - - - - - - - - - - - GSDH k141_35868_2 218284.CCDN010000007_gene3912 1.95e-49 164.0 COG0561@1|root,COG0561@2|Bacteria,1V5FB@1239|Firmicutes,4HGY8@91061|Bacilli,1ZDBI@1386|Bacillus 91061|Bacilli S hydrolases of the HAD superfamily ycsE - - - - - - - - - - - Hydrolase_3 k141_3865_2 377629.TERTU_0913 1.05e-59 185.0 COG0091@1|root,COG0091@2|Bacteria,1RH0W@1224|Proteobacteria,1S5XT@1236|Gammaproteobacteria,2PNQ2@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria J Ribosomal protein L22p/L17e rplV GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02890 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L22 k141_14512_1 218284.CCDN010000007_gene3910 7.3e-19 84.7 COG2031@1|root,COG2031@2|Bacteria,1TPCQ@1239|Firmicutes,4HAQF@91061|Bacilli,1ZECR@1386|Bacillus 91061|Bacilli I Short chain fatty acid transporter atoE - - ko:K02106 ko02020,map02020 - - - ko00000,ko00001 2.A.73.1 - - SCFA_trans k141_14512_2 218284.CCDN010000007_gene3911 1.25e-59 198.0 COG1292@1|root,COG1292@2|Bacteria,1TRS6@1239|Firmicutes,4HA7U@91061|Bacilli,1ZBRN@1386|Bacillus 91061|Bacilli M Belongs to the BCCT transporter (TC 2.A.15) family opuD_3 - - - - - - - - - - - BCCT k141_28834_1 1215092.PA6_008_00930 2.92e-35 129.0 COG0744@1|root,COG0744@2|Bacteria,1RDAQ@1224|Proteobacteria,1RMGB@1236|Gammaproteobacteria,1YCVN@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria M Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors mtgA GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008955,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0030203,GO:0034645,GO:0042546,GO:0043164,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.4.1.129 ko:K03814 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly k141_25218_2 218284.CCDN010000005_gene3446 1.42e-63 195.0 COG1006@1|root,COG1006@2|Bacteria,1V7CR@1239|Firmicutes,4HJHX@91061|Bacilli,1ZH1G@1386|Bacillus 91061|Bacilli P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali mrpC - - ko:K05567 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - Oxidored_q2 k141_29907_1 666686.B1NLA3E_06615 9.12e-113 358.0 COG2176@1|root,COG2176@2|Bacteria,1TPAG@1239|Firmicutes,4H9RF@91061|Bacilli,1ZCIB@1386|Bacillus 91061|Bacilli L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity polC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.7.7 ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_a_NI,DNA_pol3_a_NII,DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon k141_26497_1 218284.CCDN010000002_gene2274 5.91e-113 339.0 COG0488@1|root,COG0488@2|Bacteria,1TQNA@1239|Firmicutes,4H9VW@91061|Bacilli,1ZBZP@1386|Bacillus 91061|Bacilli S ABC transporter expZ - - ko:K18231 ko02010,map02010 - - - br01600,ko00000,ko00001,ko01504,ko02000 3.A.1.121.1,3.A.1.121.3 - - ABC_tran,ABC_tran_Xtn k141_37050_2 1279017.AQYJ01000025_gene572 9.05e-148 435.0 COG3297@1|root,COG3297@2|Bacteria,1NVVW@1224|Proteobacteria,1S01F@1236|Gammaproteobacteria,4684Z@72275|Alteromonadaceae 1236|Gammaproteobacteria U GspL periplasmic domain gspL GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - ko:K02461 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - GspL_C,T2SSL k141_37050_3 1453501.JELR01000001_gene2377 2.92e-68 211.0 COG3149@1|root,COG3149@2|Bacteria 2|Bacteria U Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins gspM - - ko:K02462 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSM k141_22826_1 247634.GPB2148_400 1.05e-103 328.0 COG1629@1|root,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria,1J5SG@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec k141_18145_1 649639.Bcell_3493 1.89e-52 178.0 COG2072@1|root,COG2072@2|Bacteria,1TT0U@1239|Firmicutes,4HEEM@91061|Bacilli,1ZCKW@1386|Bacillus 91061|Bacilli P FAD-NAD(P)-binding - - - - - - - - - - - - K_oxygenase,NAD_binding_9,Pyr_redox_3 k141_18145_2 218284.CCDN010000008_gene4256 1.45e-188 531.0 COG0523@1|root,COG0523@2|Bacteria,1TPCG@1239|Firmicutes,4HARN@91061|Bacilli,1ZCV4@1386|Bacillus 91061|Bacilli S GTPases (G3E family) - - - - - - - - - - - - CobW_C,cobW k141_9711_1 1453501.JELR01000002_gene990 1.01e-107 316.0 COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,1RMJJ@1236|Gammaproteobacteria,466SZ@72275|Alteromonadaceae 1236|Gammaproteobacteria KT COG3279 Response regulator of the LytR AlgR family algR - - ko:K08083 ko02020,map02020 M00493 - - ko00000,ko00001,ko00002,ko02022 - - - LytTR,Response_reg k141_9711_2 1034807.FBFL15_2424 0.000948 46.2 COG2972@1|root,COG2972@2|Bacteria,4NF45@976|Bacteroidetes,1HXAW@117743|Flavobacteriia,2P03E@237|Flavobacterium 976|Bacteroidetes T Histidine kinase - - - - - - - - - - - - His_kinase,TPR_10,TPR_12,TPR_7,TPR_8 k141_26498_1 1294265.JCM21738_480 3.42e-150 434.0 COG0405@1|root,COG0405@2|Bacteria,1TR9U@1239|Firmicutes,4HB23@91061|Bacilli,1ZCVJ@1386|Bacillus 91061|Bacilli E gamma-glutamyltransferase - - 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept k141_16885_1 1034347.CAHJ01000039_gene4691 7.51e-40 150.0 COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,4H9M4@91061|Bacilli,1ZBWR@1386|Bacillus 91061|Bacilli S Competence protein ComEC comEC - - ko:K02238 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - Competence,DUF4131,Lactamase_B k141_16885_2 1499680.CCFE01000018_gene1526 2.27e-22 87.4 2EJUP@1|root,33DJB@2|Bacteria,1VMIR@1239|Firmicutes,4HRA6@91061|Bacilli,1ZK02@1386|Bacillus 91061|Bacilli S YqzM-like protein - - - - - - - - - - - - YqzM k141_22827_1 1121938.AUDY01000002_gene453 4.73e-15 70.5 29481@1|root,2ZRNC@2|Bacteria,1W5AA@1239|Firmicutes,4I24Y@91061|Bacilli,3NG9E@45667|Halobacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_20377_1 1479235.KK366039_gene2984 5.38e-145 414.0 COG1562@1|root,COG1562@2|Bacteria,1MX4W@1224|Proteobacteria,1RRNH@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Phytoene squalene synthetase crtB GO:0003674,GO:0003824,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016108,GO:0016109,GO:0016114,GO:0016116,GO:0016117,GO:0016740,GO:0016765,GO:0042440,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046148,GO:0071704,GO:1901576 2.5.1.32,2.5.1.99 ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 M00097 R02065,R04218,R07270,R10177 RC00362,RC01101,RC02869 ko00000,ko00001,ko00002,ko01000,ko01006 - - - SQS_PSY k141_20377_2 1122214.AQWH01000005_gene1345 1.58e-215 600.0 COG2159@1|root,COG2159@2|Bacteria,1MXI7@1224|Proteobacteria,2U15G@28211|Alphaproteobacteria,2PMCG@255475|Aurantimonadaceae 28211|Alphaproteobacteria S Amidohydrolase - - 4.1.1.46 ko:K07045,ko:K14333,ko:K15063 ko00362,ko00627,ko01120,map00362,map00627,map01120 - R00821,R09278 RC00390 ko00000,ko00001,ko01000 - - - Amidohydro_2 k141_10920_1 1270196.JCKI01000005_gene3026 4.64e-25 104.0 COG1260@1|root,COG1260@2|Bacteria,4NI0F@976|Bacteroidetes,1IP24@117747|Sphingobacteriia 976|Bacteroidetes I Myo-inositol-1-phosphate synthase ino1 - 5.5.1.4 ko:K01858 ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130 - R07324 RC01804 ko00000,ko00001,ko01000 - - - Inos-1-P_synth,NAD_binding_5 k141_7393_1 218284.CCDN010000005_gene3494 5.98e-74 231.0 COG1105@1|root,COG1105@2|Bacteria,1TQ36@1239|Firmicutes,4HANU@91061|Bacilli,1ZB76@1386|Bacillus 91061|Bacilli G Belongs to the carbohydrate kinase PfkB family pfkB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046835,GO:0071704 2.7.1.56 ko:K00882 ko00051,map00051 - R02071 RC00002,RC00017 ko00000,ko00001,ko01000 - - iYO844.BSU14390 PfkB k141_34707_2 1279017.AQYJ01000027_gene1850 0.0 1308.0 COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,1RNJI@1236|Gammaproteobacteria,4655N@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG0210 Superfamily I DNA and RNA helicases uvrD GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006289,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0015616,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017116,GO:0022607,GO:0031297,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0042802,GO:0043142,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045005,GO:0046483,GO:0050896,GO:0051259,GO:0051260,GO:0051276,GO:0051716,GO:0065003,GO:0070035,GO:0070581,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C k141_34707_3 1279017.AQYJ01000027_gene1848 3.55e-177 496.0 COG1737@1|root,COG1737@2|Bacteria,1MV3U@1224|Proteobacteria,1RNC4@1236|Gammaproteobacteria,465QI@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG1737 Transcriptional regulators hexR3 - - ko:K19337 - - - - ko00000,ko03000 - - - HTH_6,SIS k141_27522_1 1468411.X2KU69_9CAUD 1.49e-15 77.0 4QDEN@10239|Viruses,4R0G3@35237|dsDNA viruses no RNA stage,4QQNS@28883|Caudovirales,4QKQB@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k141_27522_2 1538804.A0A088FAQ4_9CAUD 1.72e-72 227.0 4QCT7@10239|Viruses,4QPFU@28883|Caudovirales,4QKS9@10699|Siphoviridae 10699|Siphoviridae S iron-sulfur cluster binding - - - - - - - - - - - - - k141_27522_3 1538804.A0A088F6S9_9CAUD 3.73e-111 325.0 4QGHR@10239|Viruses,4QTRG@28883|Caudovirales,4QKSH@10699|Siphoviridae 10699|Siphoviridae S Queuosine biosynthesis protein QueC - - - - - - - - - - - - - k141_27522_4 1038859.AXAU01000029_gene79 1.45e-45 153.0 COG0720@1|root,COG0720@2|Bacteria,1RKYI@1224|Proteobacteria,2UE4U@28211|Alphaproteobacteria,3K4GI@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H 6-pyruvoyl tetrahydropterin synthase - - 4.1.2.50,4.2.3.12 ko:K01737 ko00790,ko01100,map00790,map01100 M00842,M00843 R04286,R09959 RC01117,RC02846,RC02847 ko00000,ko00001,ko00002,ko01000,ko03016 - - - PTPS k141_27522_5 1175654.A0A0S0N787_9CAUD 1.13e-92 280.0 4QH75@10239|Viruses,4QWW9@35237|dsDNA viruses no RNA stage,4QQZ4@28883|Caudovirales,4QKSF@10699|Siphoviridae 10699|Siphoviridae S GTP cyclohydrolase I activity - - - - - - - - - - - - - k141_27522_6 1175654.A0A0S0MVN0_9CAUD 4.41e-147 423.0 4QFED@10239|Viruses,4R072@35237|dsDNA viruses no RNA stage,4QPEH@28883|Caudovirales,4QN2V@10699|Siphoviridae 10699|Siphoviridae S tRNA modification - - - - - - - - - - - - - k141_27522_7 1561065.A0A0B5A0B3_9CAUD 6.53e-44 160.0 4QETH@10239|Viruses,4QPKY@28883|Caudovirales,4QMA1@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k141_27522_8 1175654.A0A0S0NAG2_9CAUD 1.77e-223 649.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k141_27522_15 462590.A9J4Y2_BPPYU 4.63e-09 61.6 4QC62@10239|Viruses,4QZ3S@35237|dsDNA viruses no RNA stage,4QTY4@28883|Caudovirales,4QM8Y@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k141_27522_16 1211114.ALIP01000125_gene150 2.29e-17 87.0 COG5449@1|root,COG5449@2|Bacteria,1QDU8@1224|Proteobacteria,1T9ZP@1236|Gammaproteobacteria,1X8GU@135614|Xanthomonadales 135614|Xanthomonadales S Uncharacterized conserved protein (DUF2163) - - - - - - - - - - - - DUF2163,Phage_BR0599 k141_12186_1 1196031.ALEG01000072_gene955 2.6e-22 89.7 29NRW@1|root,309PW@2|Bacteria,1U5GK@1239|Firmicutes,4IF7D@91061|Bacilli,1ZIZN@1386|Bacillus 91061|Bacilli S YgaB-like protein ygaB - - - - - - - - - - - YgaB k141_9712_1 218284.CCDN010000005_gene3299 9.2e-98 293.0 COG0564@1|root,COG0564@2|Bacteria,1TS1T@1239|Firmicutes,4HBRY@91061|Bacilli,1ZB25@1386|Bacillus 91061|Bacilli J Responsible for synthesis of pseudouridine from uracil rluD GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23,5.4.99.28,5.4.99.29 ko:K06177,ko:K06180 - - - - ko00000,ko01000,ko03009,ko03016 - - - PseudoU_synth_2 k141_16886_1 1453501.JELR01000001_gene1940 3.9e-126 371.0 COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,1RMIX@1236|Gammaproteobacteria,46453@72275|Alteromonadaceae 1236|Gammaproteobacteria M zinc metalloprotease rseP GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016021,GO:0016787,GO:0019219,GO:0019222,GO:0019538,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0043170,GO:0043856,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0045152,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:0140110,GO:1901564,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - ko:K11749 ko02024,ko04112,map02024,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - PDZ,PDZ_2,Peptidase_M50 k141_28835_1 1307436.PBF_19228 2e-175 496.0 COG1252@1|root,COG1252@2|Bacteria,1TR6X@1239|Firmicutes,4HA14@91061|Bacilli,1ZAV9@1386|Bacillus 91061|Bacilli C NADH dehydrogenase yumB GO:0003674,GO:0003824,GO:0003955,GO:0006091,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0019646,GO:0022900,GO:0022904,GO:0044237,GO:0045333,GO:0055114 1.6.99.3 ko:K03885 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - iYO844.BSU32100 Pyr_redox_2 k141_13360_1 218284.CCDN010000001_gene428 1.27e-95 283.0 COG2318@1|root,COG2318@2|Bacteria,1V6MV@1239|Firmicutes,4HH68@91061|Bacilli,1ZFX8@1386|Bacillus 91061|Bacilli S DinB superfamily - - - - - - - - - - - - DinB_2 k141_18146_1 1869.MB27_01440 9.66e-88 281.0 COG3459@1|root,COG3459@2|Bacteria,2IAZ0@201174|Actinobacteria,4DHXT@85008|Micromonosporales 201174|Actinobacteria G Putative carbohydrate binding domain - - 2.4.1.20 ko:K00702 ko00500,ko01100,map00500,map01100 - R00952 RC00049 ko00000,ko00001,ko01000 - GT36 - Glyco_hydro_36,Glyco_transf_36 k141_29908_1 218284.CCDN010000007_gene3785 3.67e-25 101.0 COG2206@1|root,COG2206@2|Bacteria,1TR95@1239|Firmicutes,4HB8S@91061|Bacilli,1ZCD6@1386|Bacillus 91061|Bacilli T HD domain M1-161 - - - - - - - - - - - HD,HD_5 k141_3868_1 1453501.JELR01000001_gene2226 1.47e-47 163.0 COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria,463YA@72275|Alteromonadaceae 1236|Gammaproteobacteria I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP fabF GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033817,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.179 ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - iAF1260.b1095,iAPECO1_1312.APECO1_176,iB21_1397.B21_01099,iBWG_1329.BWG_0943,iE2348C_1286.E2348C_1187,iEC042_1314.EC042_1165,iEC55989_1330.EC55989_1207,iECABU_c1320.ECABU_c13085,iECBD_1354.ECBD_2506,iECB_1328.ECB_01091,iECDH10B_1368.ECDH10B_1167,iECDH1ME8569_1439.ECDH1ME8569_1030,iECD_1391.ECD_01091,iECED1_1282.ECED1_1238,iECH74115_1262.ECH74115_1474,iECIAI1_1343.ECIAI1_1130,iECIAI39_1322.ECIAI39_2066,iECO103_1326.ECO103_1140,iECO111_1330.ECO111_1372,iECO26_1355.ECO26_1428,iECOK1_1307.ECOK1_1202,iECP_1309.ECP_1087,iECS88_1305.ECS88_1109,iECSE_1348.ECSE_1159,iECSF_1327.ECSF_0994,iECSP_1301.ECSP_1396,iECUMN_1333.ECUMN_1270,iECW_1372.ECW_m1203,iECs_1301.ECs1473,iEKO11_1354.EKO11_2739,iETEC_1333.ETEC_1160,iEcDH1_1363.EcDH1_2552,iEcE24377_1341.EcE24377A_1216,iEcSMS35_1347.EcSMS35_2032,iG2583_1286.G2583_1355,iJO1366.b1095,iJR904.b1095,iLF82_1304.LF82_0607,iNRG857_1313.NRG857_05280,iSF_1195.SF1099,iSFxv_1172.SFxv_1251,iS_1188.S1179,iUMN146_1321.UM146_11850,iWFL_1372.ECW_m1203,iY75_1357.Y75_RS05720,iZ_1308.Z1734,ic_1306.c1365 Ketoacyl-synt_C,ketoacyl-synt k141_8566_2 223926.28809778 7.56e-180 503.0 COG0457@1|root,COG0457@2|Bacteria,1NJMG@1224|Proteobacteria,1T1AW@1236|Gammaproteobacteria,1XVCF@135623|Vibrionales 135623|Vibrionales S Putative capsular polysaccharide synthesis protein - - - - - - - - - - - - NKWYS k141_8566_3 223926.28809777 9.48e-97 294.0 2B0YY@1|root,31TC3@2|Bacteria,1QJFI@1224|Proteobacteria,1THEY@1236|Gammaproteobacteria,1XV4K@135623|Vibrionales 135623|Vibrionales S O-Antigen ligase - - - - - - - - - - - - Wzy_C k141_15721_1 926561.KB900623_gene1061 1.37e-22 100.0 COG1191@1|root,COG1191@2|Bacteria,1TP9K@1239|Firmicutes,248M0@186801|Clostridia,3WAM9@53433|Halanaerobiales 186801|Clostridia K RNA polymerase sigma factor, FliA WhiG family fliA - - ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 - - - ko00000,ko00001,ko02035,ko03021 - - - Sigma70_r2,Sigma70_r3,Sigma70_r4 k141_15721_2 543728.Vapar_2282 1.62e-68 221.0 COG1338@1|root,COG1338@2|Bacteria,1MVBU@1224|Proteobacteria,2VIU6@28216|Betaproteobacteria,4AC06@80864|Comamonadaceae 28216|Betaproteobacteria N Plays a role in the flagellum-specific transport system fliP - - ko:K02419 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - FliP k141_15721_4 13690.CP98_01038 5.8e-10 59.3 COG1886@1|root,COG1886@2|Bacteria,1RGWT@1224|Proteobacteria,2UHHH@28211|Alphaproteobacteria,2K5SF@204457|Sphingomonadales 204457|Sphingomonadales N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation fliN - - ko:K02417 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 - - FliMN_C k141_22828_1 1294265.JCM21738_4491 1.3e-245 681.0 COG0365@1|root,COG0365@2|Bacteria,1TQTI@1239|Firmicutes,4H9PN@91061|Bacilli,1ZCDC@1386|Bacillus 91061|Bacilli I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases ytcI GO:0003674,GO:0003824,GO:0003996,GO:0004321,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0015645,GO:0016053,GO:0016405,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0016874,GO:0016877,GO:0016878,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901576 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 - - - AMP-binding,AMP-binding_C k141_14514_1 518766.Rmar_1228 4.61e-71 238.0 COG1480@1|root,COG1480@2|Bacteria,4NEHV@976|Bacteroidetes,1FJ41@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes S 7TM-HD extracellular - - - ko:K07037 - - - - ko00000 - - - 7TM-7TMR_HD,7TMR-HDED,HD k141_16887_2 1042377.AFPJ01000043_gene900 1.27e-15 78.6 COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,1RMYY@1236|Gammaproteobacteria,465WZ@72275|Alteromonadaceae 1236|Gammaproteobacteria M Mechanosensitive ion channel kefA - - - - - - - - - - - MS_channel k141_13361_1 247639.MGP2080_02515 9.94e-63 205.0 COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,1RN2A@1236|Gammaproteobacteria 1236|Gammaproteobacteria E The glycine cleavage system catalyzes the degradation of glycine - - 2.1.2.10 ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 M00532 R01221,R02300,R04125 RC00022,RC00069,RC00183,RC02834 ko00000,ko00001,ko00002,ko01000 - - - DUF1989,GCV_T,GCV_T_C k141_20378_1 218284.CCDN010000004_gene3091 1.59e-110 333.0 COG1109@1|root,COG1109@2|Bacteria,1TP2N@1239|Firmicutes,4HADU@91061|Bacilli,1ZBEM@1386|Bacillus 91061|Bacilli G Phosphoglucomutase pgcA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 5.4.2.2 ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00549 R00959,R01057,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV k141_1396_1 218284.CCDN010000007_gene3786 9.25e-226 646.0 COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,4HAHY@91061|Bacilli,1ZB8F@1386|Bacillus 91061|Bacilli L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrA - 5.99.1.3 ko:K02469 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseA_C,DNA_topoisoIV k141_31190_1 223926.28809366 7.24e-235 672.0 COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,1RMWN@1236|Gammaproteobacteria,1XUIC@135623|Vibrionales 135623|Vibrionales C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family nasA - - ko:K00372 ko00910,ko01120,map00910,map01120 M00531 R00798,R01106 RC02812 ko00000,ko00001,ko00002,ko01000 - - - Fer2_BFD,Molybdop_Fe4S4,Molybdopterin,Molydop_binding k141_31190_2 223926.28809365 5.19e-163 462.0 COG0007@1|root,COG0007@2|Bacteria,1RBE1@1224|Proteobacteria,1SYIY@1236|Gammaproteobacteria,1XTGC@135623|Vibrionales 135623|Vibrionales H Belongs to the precorrin methyltransferase family - - 2.1.1.107 ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R03194 RC00003,RC00871 ko00000,ko00001,ko00002,ko01000 - - - TP_methylase k141_31190_3 1280001.BAOA01000070_gene2873 2.79e-205 570.0 COG0547@1|root,COG0547@2|Bacteria,1QJ8Q@1224|Proteobacteria,1RY26@1236|Gammaproteobacteria,1XTQE@135623|Vibrionales 135623|Vibrionales E Glycosyl transferase family, helical bundle domain - - - - - - - - - - - - Glycos_trans_3N,Glycos_transf_3 k141_31190_4 674977.VMC_29740 1.3e-199 556.0 COG0412@1|root,COG0412@2|Bacteria,1MW7S@1224|Proteobacteria,1RPGK@1236|Gammaproteobacteria,1XTF6@135623|Vibrionales 135623|Vibrionales Q Dienelactone hydrolase family - - 3.1.1.45 ko:K01061 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 - R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222 RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 - - - DLH k141_31190_5 674977.VMC_29730 3.39e-103 302.0 COG3707@1|root,COG3707@2|Bacteria,1QDVF@1224|Proteobacteria,1SIGY@1236|Gammaproteobacteria,1XWZ8@135623|Vibrionales 135623|Vibrionales K COG3707 Response regulator with - - - ko:K07183 - - - - ko00000,ko02022 - - - ANTAR k141_31190_6 223926.28809359 0.0 872.0 COG0715@1|root,COG0715@2|Bacteria,1MWDN@1224|Proteobacteria,1RPUP@1236|Gammaproteobacteria,1XVUH@135623|Vibrionales 135623|Vibrionales P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components - - - ko:K15576 ko00910,ko02010,map00910,map02010 M00438 - - ko00000,ko00001,ko00002,ko02000 3.A.1.16.1,3.A.1.16.2 - - NMT1_2 k141_31190_7 1219076.N646_4428 1.83e-209 581.0 COG0600@1|root,COG0600@2|Bacteria,1MU6Q@1224|Proteobacteria,1RPP1@1236|Gammaproteobacteria,1XU0I@135623|Vibrionales 135623|Vibrionales P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component - - - ko:K15577 ko00910,ko02010,map00910,map02010 M00438 - - ko00000,ko00001,ko00002,ko02000 3.A.1.16.1,3.A.1.16.2 - - BPD_transp_1 k141_27544_2 1294265.JCM21738_1951 7.45e-33 124.0 COG0370@1|root,COG0370@2|Bacteria,1TP7E@1239|Firmicutes,4HBCS@91061|Bacilli,1ZCZU@1386|Bacillus 91061|Bacilli P transporter of a GTP-driven Fe(2 ) uptake system feoB - - ko:K04759 - - - - ko00000,ko02000 9.A.8.1 - iSB619.SA_RS13395 FeoB_C,FeoB_N,Gate k141_1413_1 1384057.CD33_03445 2.27e-81 246.0 COG0745@1|root,COG0745@2|Bacteria,1TSWT@1239|Firmicutes,4HBSC@91061|Bacilli,3IXI9@400634|Lysinibacillus 91061|Bacilli K Heme transporter CcmC hssR - - ko:K02483 - - - - ko00000,ko02022 - - - Response_reg,Trans_reg_C k141_9750_2 218284.CCDN010000001_gene275 1.93e-139 401.0 COG1473@1|root,COG1473@2|Bacteria,1TQ7R@1239|Firmicutes,4HB6M@91061|Bacilli,1ZB9M@1386|Bacillus 91061|Bacilli S amidohydrolase amhX - - ko:K14665 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 k141_19261_1 218284.CCDN010000001_gene1007 2.46e-300 824.0 COG0364@1|root,COG0364@2|Bacteria,1TPYF@1239|Firmicutes,4HA73@91061|Bacilli,1ZCZ3@1386|Bacillus 91061|Bacilli G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone zwf - 1.1.1.363,1.1.1.49 ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 M00004,M00006,M00008 R00835,R02736,R10907 RC00001,RC00066 ko00000,ko00001,ko00002,ko01000,ko04147 - - - G6PD_C,G6PD_N k141_367_1 562970.Btus_1754 1.98e-08 57.8 COG0142@1|root,COG0142@2|Bacteria,1TR0U@1239|Firmicutes,4H9RH@91061|Bacilli,27855@186823|Alicyclobacillaceae 91061|Bacilli H Belongs to the FPP GGPP synthase family hepT GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.30,2.5.1.83 ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 - R09245,R09247 RC00279 ko00000,ko00001,ko01000,ko01006 - - - polyprenyl_synt k141_367_3 330214.NIDE0255 1.19e-08 56.6 COG1826@1|root,COG1826@2|Bacteria 2|Bacteria U protein secretion tatA - - ko:K03116 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - MttA_Hcf106 k141_26808_1 218284.CCDN010000002_gene2266 4.35e-144 418.0 COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,1TPXQ@1239|Firmicutes,4HA3C@91061|Bacilli,1ZBHE@1386|Bacillus 91061|Bacilli C Catalyzes the reversible hydration of fumarate to (S)- malate fumA - 4.2.1.2 ko:K01676 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - - Fumerase,Fumerase_C k141_4091_1 1307436.PBF_15774 4.07e-33 127.0 COG2340@1|root,COG2340@2|Bacteria,1V6GZ@1239|Firmicutes,4HJ21@91061|Bacilli,1ZDSK@1386|Bacillus 91061|Bacilli J protein with SCP PR1 domains - - - - - - - - - - - - CAP k141_10013_1 1243664.CAVL020000006_gene4945 5.66e-80 257.0 COG0751@1|root,COG0751@2|Bacteria,1TNZ7@1239|Firmicutes,4H9NT@91061|Bacilli,1ZDF3@1386|Bacillus 91061|Bacilli J Glycyl-tRNA synthetase beta subunit glyS - 6.1.1.14 ko:K01879 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_1,tRNA_synt_2f k141_10013_2 1294265.JCM21738_3316 3.14e-10 59.3 COG0752@1|root,COG0752@2|Bacteria,1TPW8@1239|Firmicutes,4HBCF@91061|Bacilli,1ZCKP@1386|Bacillus 91061|Bacilli J glycyl-tRNA synthetase alpha subunit glyQ - 6.1.1.14 ko:K01878 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2e k141_34912_1 243274.THEMA_01220 2.47e-35 138.0 COG0126@1|root,COG0149@1|root,COG0126@2|Bacteria,COG0149@2|Bacteria,2GBXW@200918|Thermotogae 200918|Thermotogae F belongs to the phosphoglycerate kinase family pgk GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.3,5.3.1.1 ko:K00927,ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01015,R01512 RC00002,RC00043,RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGK,TIM k141_7542_2 1294265.JCM21738_564 3.7e-80 253.0 COG4191@1|root,COG4191@2|Bacteria,1VCNJ@1239|Firmicutes,4HVBX@91061|Bacilli,1ZS41@1386|Bacillus 91061|Bacilli T Histidine kinase - - 2.7.13.3 ko:K02491,ko:K13533 ko02020,map02020 M00485 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - 5TM-5TMR_LYT,HATPase_c,HisKA,LytTR,MASE3,PAS,PAS_3,PAS_4,PAS_9 k141_20614_1 223926.28808701 3.4e-262 727.0 COG1109@1|root,COG1109@2|Bacteria,1QUGD@1224|Proteobacteria,1RQME@1236|Gammaproteobacteria,1XVES@135623|Vibrionales 135623|Vibrionales G Phosphoglucomutase phosphomannomutase alpha beta subunit - - 5.4.2.8 ko:K01840 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 M00114 R01818 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV k141_11196_1 218284.CCDN010000004_gene3068 6.17e-270 745.0 COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,4H9SZ@91061|Bacilli,1ZAX7@1386|Bacillus 91061|Bacilli E Sodium alanine symporter alsT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03310 - - - - ko00000 2.A.25 - - Na_Ala_symp k141_28968_1 218284.CCDN010000001_gene1873 1.48e-92 286.0 COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,4HAAP@91061|Bacilli,1ZB4E@1386|Bacillus 91061|Bacilli S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay rnjB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 - ko:K12574 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - Lactamase_B,RMMBL k141_26810_1 1294265.JCM21738_4737 4.3e-88 283.0 COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H9SA@91061|Bacilli,1ZD7B@1386|Bacillus 91061|Bacilli M COG0744 Membrane carboxypeptidase (penicillin-binding protein) pbp1B - 2.4.1.129 ko:K03693,ko:K12551 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase k141_25472_1 1294265.JCM21738_3425 1.38e-75 233.0 COG0022@1|root,COG0022@2|Bacteria,1TP3J@1239|Firmicutes,4HAP6@91061|Bacilli,1ZC0X@1386|Bacillus 91061|Bacilli C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit bfmBAB - 1.2.4.4 ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 M00036 R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00027,RC00627,RC02743,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU24040 Transket_pyr,Transketolase_C k141_25472_2 1294265.JCM21738_3424 2.82e-108 318.0 COG1071@1|root,COG1071@2|Bacteria,1TQDG@1239|Firmicutes,4HBEQ@91061|Bacilli,1ZCCJ@1386|Bacillus 91061|Bacilli C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit bfmBAA - 1.2.4.4 ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 M00036 R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00027,RC00627,RC02743,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS07640 E1_dh k141_10014_1 218284.CCDN010000006_gene3612 2.89e-113 335.0 COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,4HAKI@91061|Bacilli,1ZAZB@1386|Bacillus 91061|Bacilli G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis eno GO:0001968,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005518,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035375,GO:0042866,GO:0043236,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0044877,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050840,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 - - - Enolase_C,Enolase_N k141_23149_2 218284.CCDN010000001_gene1282 2.09e-97 286.0 COG0512@1|root,COG0512@2|Bacteria,1TT9R@1239|Firmicutes,4H9XP@91061|Bacilli,1ZBB7@1386|Bacillus 91061|Bacilli EH Anthranilate synthase trpG - 4.1.3.27 ko:K01658 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - GATase k141_8831_1 357804.Ping_0766 1.38e-96 299.0 COG0662@1|root,COG0836@1|root,COG0662@2|Bacteria,COG0836@2|Bacteria,1MV39@1224|Proteobacteria,1RNQI@1236|Gammaproteobacteria,2QIS8@267894|Psychromonadaceae 1236|Gammaproteobacteria M Mannose-6-phosphate isomerase cpsB - 2.7.7.13,5.3.1.8 ko:K00971,ko:K16011 ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025 M00114,M00361,M00362 R00885,R01819 RC00002,RC00376 ko00000,ko00001,ko00002,ko01000 - - - MannoseP_isomer,NTP_transferase k141_11197_1 1294265.JCM21738_3034 1.82e-143 426.0 COG3973@1|root,COG3973@2|Bacteria,1TP39@1239|Firmicutes,4H9Y5@91061|Bacilli,1ZAWP@1386|Bacillus 91061|Bacilli L DNA helicase helD - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_19,UvrD-helicase,UvrD_C,UvrD_C_2 k141_27648_1 218284.CCDN010000008_gene4195 3.87e-154 437.0 COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,4HAMU@91061|Bacilli,1ZC73@1386|Bacillus 91061|Bacilli E Belongs to the cysteine synthase cystathionine beta- synthase family ytkP GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03601,R04859 RC00020,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 - - - PALP k141_1587_1 218284.CCDN010000001_gene656 5.66e-100 302.0 COG1055@1|root,COG1055@2|Bacteria,1TPNN@1239|Firmicutes,4HAIC@91061|Bacilli,1ZBBN@1386|Bacillus 91061|Bacilli P Membrane arsB_2 - - ko:K03893 - - - - ko00000,ko02000 2.A.45.1,3.A.4.1 - - CitMHS k141_31320_1 218284.CCDN010000001_gene510 1.03e-96 288.0 COG2186@1|root,COG2186@2|Bacteria,1V3Z4@1239|Firmicutes,4HG61@91061|Bacilli,1ZQ57@1386|Bacillus 91061|Bacilli K helix_turn_helix gluconate operon transcriptional repressor lutR_1 - - ko:K05799 - - - - ko00000,ko03000 - - - FCD,GntR k141_11198_1 1042377.AFPJ01000013_gene1741 8.41e-104 305.0 COG1432@1|root,COG1432@2|Bacteria,1MX5C@1224|Proteobacteria,1RSP8@1236|Gammaproteobacteria,46600@72275|Alteromonadaceae 1236|Gammaproteobacteria S OST-HTH/LOTUS domain - - - - - - - - - - - - NYN,OST-HTH k141_37231_1 218284.CCDN010000005_gene3355 1.68e-90 266.0 2C0DW@1|root,30W9V@2|Bacteria,1V5EY@1239|Firmicutes,4HI10@91061|Bacilli,1ZQRY@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_30066_1 523791.Kkor_0376 1.2e-52 181.0 COG0654@1|root,COG0654@2|Bacteria,1R7UC@1224|Proteobacteria,1S1B9@1236|Gammaproteobacteria,1XQV5@135619|Oceanospirillales 135619|Oceanospirillales CH FAD binding domain - - 1.14.13.9 ko:K00486 ko00380,ko01100,map00380,map01100 M00038 R01960 RC00046 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_3 k141_30066_2 523791.Kkor_0377 3.57e-206 582.0 COG3844@1|root,COG3844@2|Bacteria,1MUKN@1224|Proteobacteria,1RPY3@1236|Gammaproteobacteria,1XMD8@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively kynU - 3.7.1.3 ko:K01556 ko00380,ko01100,map00380,map01100 M00038 R00987,R02668,R03936 RC00284,RC00415 ko00000,ko00001,ko00002,ko01000 - - - Aminotran_5 k141_30066_3 1210884.HG799470_gene14485 2.65e-27 110.0 COG1878@1|root,COG1878@2|Bacteria 2|Bacteria S arylformamidase activity - - - - - - - - - - - - Cyclase k141_13669_1 1279017.AQYJ01000023_gene3247 6.76e-186 546.0 COG4223@1|root,COG4223@2|Bacteria,1N10X@1224|Proteobacteria,1RYCQ@1236|Gammaproteobacteria,46D2D@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF1631) - - - - - - - - - - - - DUF1631 k141_13669_2 1453501.JELR01000006_gene14 3.34e-20 92.0 COG4223@1|root,COG4223@2|Bacteria,1N10X@1224|Proteobacteria,1RYCQ@1236|Gammaproteobacteria,46D2D@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF1631) - - - - - - - - - - - - DUF1631 k141_21847_2 218284.CCDN010000006_gene3656 1.12e-99 307.0 COG0556@1|root,COG0556@2|Bacteria,1TPKB@1239|Firmicutes,4HB81@91061|Bacilli,1ZC50@1386|Bacillus 91061|Bacilli L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage uvrB - - ko:K03702 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - Helicase_C,ResIII,UVR,UvrB k141_10015_2 218284.CCDN010000005_gene3478 1.03e-80 240.0 2E71A@1|root,331JZ@2|Bacteria,1VG6F@1239|Firmicutes,4HNSV@91061|Bacilli,1ZFRN@1386|Bacillus 91061|Bacilli S YugN-like family yugN - - - - - - - - - - - YugN k141_33792_1 1042377.AFPJ01000023_gene657 3.4e-293 895.0 COG1361@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4932@2|Bacteria,1QUEG@1224|Proteobacteria 1224|Proteobacteria M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - - - - - - - - - - SdrD_B k141_12510_3 1279017.AQYJ01000028_gene2391 7.24e-80 247.0 COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,1RN2M@1236|Gammaproteobacteria,464V2@72275|Alteromonadaceae 1236|Gammaproteobacteria H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate ribD GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006725,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008703,GO:0008835,GO:0009058,GO:0009110,GO:0009231,GO:0009451,GO:0009987,GO:0016070,GO:0016491,GO:0016614,GO:0016616,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0034641,GO:0036094,GO:0042364,GO:0042726,GO:0042727,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.1.1.193,3.5.4.26 ko:K01498,ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 M00125 R03458,R03459 RC00204,RC00933 ko00000,ko00001,ko00002,ko01000 - - iB21_1397.B21_00366,iECBD_1354.ECBD_3247,iECB_1328.ECB_00362,iECD_1391.ECD_00362,iECED1_1282.ECED1_0437,iECNA114_1301.ECNA114_0391,iECSF_1327.ECSF_0374,iEcolC_1368.EcolC_3219,iJN746.PP_0514,iLF82_1304.LF82_1880,iNRG857_1313.NRG857_01945,iYL1228.KPN_00366,ic_1306.c0524 RibD_C,dCMP_cyt_deam_1 k141_4095_1 983545.Glaag_2690 4.2e-89 280.0 COG1115@1|root,COG1115@2|Bacteria,1MUI3@1224|Proteobacteria,1RMNF@1236|Gammaproteobacteria,464Z4@72275|Alteromonadaceae 1236|Gammaproteobacteria E alanine symporter dagA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03310 - - - - ko00000 2.A.25 - - Na_Ala_symp k141_37232_1 926569.ANT_13760 0.000378 43.9 COG0632@1|root,COG0632@2|Bacteria,2G6V7@200795|Chloroflexi 200795|Chloroflexi L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB ruvA - 3.6.4.12 ko:K03550 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - HHH_5,RuvA_C,RuvA_N k141_37232_2 479434.Sthe_2189 1.34e-22 93.6 COG1595@1|root,COG1595@2|Bacteria,2G99U@200795|Chloroflexi,27YIE@189775|Thermomicrobia 189775|Thermomicrobia K Sigma-70 region 2 - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_20631_1 1294265.JCM21738_3232 1.14e-42 139.0 COG4481@1|root,COG4481@2|Bacteria,1VEQ7@1239|Firmicutes,4HNHU@91061|Bacilli,1ZIUV@1386|Bacillus 91061|Bacilli S protein conserved in bacteria yyzM - - - - - - - - - - - DUF951 k141_20631_2 1294265.JCM21738_3231 2.42e-59 191.0 COG0668@1|root,COG0668@2|Bacteria,1TR9Z@1239|Firmicutes,4HCB8@91061|Bacilli,1ZCW4@1386|Bacillus 91061|Bacilli M Mechanosensitive ion channel ykuT - - ko:K22044 - - - - ko00000,ko02000 1.A.23.3 - - MS_channel k141_17087_1 1294265.JCM21738_4521 1.76e-101 296.0 COG2318@1|root,COG2318@2|Bacteria,1V6UF@1239|Firmicutes,4HIPX@91061|Bacilli,1ZD6H@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF664) - - - - - - - - - - - - DUF664 k141_11219_1 218284.CCDN010000001_gene684 1.73e-18 87.4 COG0457@1|root,COG0457@2|Bacteria,1V1HX@1239|Firmicutes,4HG5V@91061|Bacilli,1ZCPW@1386|Bacillus 91061|Bacilli S COG0457 FOG TPR repeat yrrB - - - - - - - - - - - TPR_1,TPR_16,TPR_2,TPR_6,TPR_8 k141_11219_2 218284.CCDN010000001_gene683 2.06e-21 91.3 COG0482@1|root,COG0482@2|Bacteria,1TPIZ@1239|Firmicutes,4HBJ6@91061|Bacilli,1ZBWQ@1386|Bacillus 91061|Bacilli J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 mnmA GO:0002097,GO:0002098,GO:0002143,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 2.8.1.13 ko:K00566 ko04122,map04122 - R08700 RC02313,RC02315 ko00000,ko00001,ko01000,ko03016 - - - tRNA_Me_trans k141_28976_1 1469557.JSWF01000030_gene3523 0.000641 48.5 COG3291@1|root,COG3391@1|root,COG4447@1|root,COG4935@1|root,COG3291@2|Bacteria,COG3391@2|Bacteria,COG4447@2|Bacteria,COG4935@2|Bacteria,4NEJ8@976|Bacteroidetes,1HYZP@117743|Flavobacteriia 976|Bacteroidetes O cellulase activity - - - - - - - - - - - - CUB,MAM,PA,TSP_3,fn3 k141_18374_1 1042377.AFPJ01000036_gene1146 1.09e-136 405.0 COG2173@1|root,COG3876@1|root,COG2173@2|Bacteria,COG3876@2|Bacteria,1MX3S@1224|Proteobacteria,1RSA3@1236|Gammaproteobacteria,465YH@72275|Alteromonadaceae 1236|Gammaproteobacteria M protein conserved in bacteria - - - - - - - - - - - - DUF1343 k141_18374_2 1042377.AFPJ01000036_gene1146 2.72e-99 309.0 COG2173@1|root,COG3876@1|root,COG2173@2|Bacteria,COG3876@2|Bacteria,1MX3S@1224|Proteobacteria,1RSA3@1236|Gammaproteobacteria,465YH@72275|Alteromonadaceae 1236|Gammaproteobacteria M protein conserved in bacteria - - - - - - - - - - - - DUF1343 k141_18374_3 1042377.AFPJ01000036_gene1145 2.42e-316 879.0 COG1982@1|root,COG1982@2|Bacteria,1MWK4@1224|Proteobacteria,1RMVF@1236|Gammaproteobacteria,464W7@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG1982 Arginine lysine ornithine decarboxylases - - 4.1.1.19 ko:K01584,ko:K01585 ko00330,ko01100,map00330,map01100 M00133 R00566 RC00299 ko00000,ko00001,ko00002,ko01000 - - - OKR_DC_1,OKR_DC_1_C k141_13688_1 1136163.M565_ctg1P1650 1.26e-168 476.0 COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,1RMAQ@1236|Gammaproteobacteria,1XVPF@135623|Vibrionales 135623|Vibrionales L COG3547 Transposase and inactivated derivatives - - - - - - - - - - - - DEDD_Tnp_IS110,Transposase_20 k141_13688_2 314292.VAS14_11604 1.93e-81 245.0 COG1670@1|root,COG1670@2|Bacteria,1N6Q1@1224|Proteobacteria,1SBHR@1236|Gammaproteobacteria,1XXDV@135623|Vibrionales 135623|Vibrionales J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins - - - - - - - - - - - - Acetyltransf_3 k141_32432_1 1042377.AFPJ01000043_gene844 1.54e-131 394.0 COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria,464PM@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG1404 Subtilisin-like serine proteases - GO:0005575,GO:0005576 - ko:K14645 ko02024,map02024 - - - ko00000,ko00001,ko01000,ko01002,ko03110 - - - PKD,PPC,P_proprotein,Peptidase_S8 k141_12546_1 42565.FP66_07245 1.24e-26 104.0 COG0825@1|root,COG0825@2|Bacteria,1MURN@1224|Proteobacteria,1RNN8@1236|Gammaproteobacteria,1XI2H@135619|Oceanospirillales 135619|Oceanospirillales I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA accA - 2.1.3.15,6.4.1.2 ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - ACCA k141_12546_2 42565.FP66_07250 2.36e-44 159.0 COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,1RP0K@1236|Gammaproteobacteria,1XI0M@135619|Oceanospirillales 135619|Oceanospirillales L DNA polymerase dnaE - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon k141_5261_1 218284.CCDN010000001_gene90 4.4e-42 154.0 COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,4H9VQ@91061|Bacilli,1ZASE@1386|Bacillus 91061|Bacilli M Penicillin-binding Protein pbpX GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - - PASTA,PBP_dimer,Transpeptidase k141_5261_2 218284.CCDN010000001_gene89 1.88e-136 405.0 COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,4H9VQ@91061|Bacilli,1ZBC0@1386|Bacillus 91061|Bacilli M stage V sporulation protein D spoVD - - ko:K08384 ko00550,map00550 - - - ko00000,ko00001,ko01011 - - - PASTA,PBP_dimer,Transpeptidase k141_617_1 1131730.BAVI_03879 3.42e-130 384.0 COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HANF@91061|Bacilli,1ZS27@1386|Bacillus 91061|Bacilli T Histidine kinase - - - - - - - - - - - - HAMP,HATPase_c,HisKA k141_11220_1 1219076.N646_1610 6.79e-154 442.0 COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RMFF@1236|Gammaproteobacteria,1XT11@135623|Vibrionales 135623|Vibrionales C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes lpdA GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0045250,GO:0045254,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyr_redox_2,Pyr_redox_dim k141_19493_1 218284.CCDN010000010_gene4373 1.13e-175 523.0 COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,4HA24@91061|Bacilli,1ZDK0@1386|Bacillus 91061|Bacilli K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoC GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 k141_34945_1 1178482.BJB45_01840 3.74e-85 271.0 COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,1RPAV@1236|Gammaproteobacteria,1XHFN@135619|Oceanospirillales 135619|Oceanospirillales L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA ligA - 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - - BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5 k141_37243_1 1294265.JCM21738_928 1.37e-120 352.0 COG2008@1|root,COG2008@2|Bacteria,1TPZI@1239|Firmicutes,4HAM3@91061|Bacilli,1ZD31@1386|Bacillus 91061|Bacilli E Threonine aldolase - - - - - - - - - - - - Beta_elim_lyase k141_20632_1 1042377.AFPJ01000030_gene447 6.41e-143 429.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MV8W@1224|Proteobacteria,1RMQA@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Outer membrane receptor proteins mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec k141_5262_1 78245.Xaut_2777 0.00037 45.8 COG1595@1|root,COG1595@2|Bacteria,1N1KW@1224|Proteobacteria,2UCAH@28211|Alphaproteobacteria,3F2C2@335928|Xanthobacteraceae 28211|Alphaproteobacteria K ECF sigma factor - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_7559_1 545693.BMQ_1330 1.02e-97 290.0 COG2171@1|root,COG2171@2|Bacteria,1TQUJ@1239|Firmicutes,4H9KY@91061|Bacilli,1ZBFG@1386|Bacillus 91061|Bacilli E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate dapH - 2.3.1.117,2.3.1.89 ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 M00016,M00525 R04364,R04365 RC00004,RC01136 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU14180 DapH_N,Hexapep k141_18376_1 1279017.AQYJ01000027_gene1918 1.15e-80 242.0 COG3160@1|root,COG3160@2|Bacteria,1RHBB@1224|Proteobacteria,1S420@1236|Gammaproteobacteria,4678R@72275|Alteromonadaceae 1236|Gammaproteobacteria K Belongs to the Rsd AlgQ family rsd GO:0000988,GO:0000989,GO:0003674,GO:0008150,GO:0009889,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2001141 - ko:K07740 - - - - ko00000 - - - Rsd_AlgQ k141_8851_1 1208321.D104_10330 3.28e-148 423.0 COG0346@1|root,COG0346@2|Bacteria,1MVVU@1224|Proteobacteria,1RQQE@1236|Gammaproteobacteria,1XKWW@135619|Oceanospirillales 135619|Oceanospirillales E PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - - - - - - - - - - Glyoxalase k141_8851_2 491952.Mar181_2389 2.76e-120 359.0 COG4447@1|root,COG4447@2|Bacteria,1RCNG@1224|Proteobacteria,1S1N2@1236|Gammaproteobacteria,1XKDC@135619|Oceanospirillales 135619|Oceanospirillales S protein related to plant photosystem II stability - - - - - - - - - - - - PSII_BNR k141_618_1 1294265.JCM21738_3026 5.33e-104 305.0 2DPHP@1|root,32UM5@2|Bacteria,1VBTA@1239|Firmicutes,4HKSX@91061|Bacilli,1ZBMR@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_17088_1 1569209.BBPH01000003_gene1688 1.76e-08 57.4 COG3034@1|root,COG3034@2|Bacteria,1MXY6@1224|Proteobacteria,2TS2U@28211|Alphaproteobacteria,2PX2Z@265|Paracoccus 28211|Alphaproteobacteria S L,D-transpeptidase catalytic domain - - - - - - - - - - - - YkuD k141_11221_1 218284.CCDN010000008_gene4257 2.64e-58 190.0 COG0701@1|root,COG0701@2|Bacteria,1TQHK@1239|Firmicutes,4HB25@91061|Bacilli,1ZC03@1386|Bacillus 91061|Bacilli S permeases - - - ko:K07089 - - - - ko00000 - - - ArsP_1 k141_11221_2 218284.CCDN010000008_gene4258 4.42e-08 53.5 COG3689@1|root,COG3689@2|Bacteria,1V3EX@1239|Firmicutes,4HG9F@91061|Bacilli,1ZAQN@1386|Bacillus 91061|Bacilli S membrane - - - ko:K08986 - - - - ko00000 - - - DUF1980 k141_25496_1 1453501.JELR01000001_gene2591 0.0 1541.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,464AK@72275|Alteromonadaceae 1236|Gammaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran k141_25496_2 1323663.AROI01000031_gene1930 7.07e-11 62.8 COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,1S2IK@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - - - - - - - - - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 k141_21867_1 218284.CCDN010000001_gene1158 1.53e-147 436.0 COG1205@1|root,COG1205@2|Bacteria,1TSPA@1239|Firmicutes,4H9T2@91061|Bacilli,1ZDM5@1386|Bacillus 91061|Bacilli L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster yprA GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - ko:K06877 - - - - ko00000 - - - DEAD,DUF1998,Helicase_C k141_34946_1 84531.JMTZ01000053_gene1548 9.52e-78 241.0 COG0491@1|root,COG0491@2|Bacteria,1P5NJ@1224|Proteobacteria,1S04Y@1236|Gammaproteobacteria,1XBW9@135614|Xanthomonadales 135614|Xanthomonadales S Metallo-beta-lactamase superfamily - - 3.5.2.6 ko:K17837 ko01501,map01501 - R06363 RC01499 ko00000,ko00001,ko01000 - - - Lactamase_B k141_33806_1 876044.IMCC3088_849 5.98e-10 60.8 COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,1RMEN@1236|Gammaproteobacteria,1J4SX@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family gltT - - ko:K03309 - - - - ko00000 2.A.23 - - SDF k141_18377_1 1329516.JPST01000013_gene346 0.000387 45.4 2DB7M@1|root,2Z7MM@2|Bacteria,1UXYU@1239|Firmicutes,4HAVT@91061|Bacilli,27BQD@186824|Thermoactinomycetaceae 91061|Bacilli S Spore germination B3/ GerAC like, C-terminal - - - ko:K06312 - - - - ko00000 - - - Spore_GerAC k141_18377_2 1408254.T458_22640 2.31e-19 87.8 COG0531@1|root,COG0531@2|Bacteria,1TZQ6@1239|Firmicutes,4ISWZ@91061|Bacilli,2777R@186822|Paenibacillaceae 91061|Bacilli E Spore germination protein yndE7 GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - ko:K06311 - - - - ko00000,ko02000 2.A.3.9.4 - - Spore_permease k141_26845_1 1279017.AQYJ01000029_gene3432 1.41e-103 315.0 COG3106@1|root,COG3106@2|Bacteria,1MX6E@1224|Proteobacteria,1RQ05@1236|Gammaproteobacteria,464CF@72275|Alteromonadaceae 1236|Gammaproteobacteria S YcjX-like family, DUF463 ycjX - - ko:K06918 - - - - ko00000 - - - DUF463 k141_619_1 1042377.AFPJ01000036_gene1148 2.6e-83 260.0 COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,1RQX2@1236|Gammaproteobacteria,463YN@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG0277 FAD FMN-containing dehydrogenases glcD GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0033554,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616 1.1.3.15 ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001,ko01000 - - iJN746.PP_3745,iLF82_1304.LF82_0831,iNRG857_1313.NRG857_14750 FAD-oxidase_C,FAD_binding_4 k141_34947_1 1121946.AUAX01000028_gene5814 2.46e-75 239.0 COG2873@1|root,COG2873@2|Bacteria,2I2EB@201174|Actinobacteria,4DMJF@85008|Micromonosporales 201174|Actinobacteria E Cys/Met metabolism PLP-dependent enzyme cysD - 2.5.1.49 ko:K01740 ko00270,ko01100,map00270,map01100 - R01287,R04859 RC00020,RC02821,RC02848 ko00000,ko00001,ko01000 - - - Cys_Met_Meta_PP k141_36036_1 218284.CCDN010000001_gene1807 5.21e-80 257.0 COG0323@1|root,COG0323@2|Bacteria,1TPGK@1239|Firmicutes,4HB34@91061|Bacilli,1ZB9X@1386|Bacillus 91061|Bacilli L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex mutL GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032300,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1990391 - ko:K03572 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - DNA_mis_repair,HATPase_c_3,MutL_C k141_10051_1 218284.CCDN010000001_gene1427 5.79e-94 284.0 COG2340@1|root,COG2340@2|Bacteria,1TSUX@1239|Firmicutes,4HDMJ@91061|Bacilli,1ZB45@1386|Bacillus 91061|Bacilli G protein with SCP PR1 domains - - - - - - - - - - - - CAP,CAP_assoc_N,SLH k141_31334_1 1042377.AFPJ01000012_gene1387 1.82e-52 175.0 COG3346@1|root,COG3346@2|Bacteria,1MZUH@1224|Proteobacteria,1S8S0@1236|Gammaproteobacteria,4684Q@72275|Alteromonadaceae 1236|Gammaproteobacteria S SURF1-like protein surf1 - - ko:K14998 - - - - ko00000,ko03029 3.D.4.8 - - SURF1 k141_31334_3 1453501.JELR01000002_gene1072 3.54e-199 553.0 COG1845@1|root,COG1845@2|Bacteria,1MUCK@1224|Proteobacteria,1RN9D@1236|Gammaproteobacteria,464F5@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3 coxC - 1.9.3.1 ko:K02276 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.4,3.D.4.6 - - COX3 k141_18378_1 1042377.AFPJ01000004_gene334 2.13e-18 85.5 COG0845@1|root,COG1994@1|root,COG0845@2|Bacteria,COG1994@2|Bacteria,1MW9I@1224|Proteobacteria,1RRTY@1236|Gammaproteobacteria,4685K@72275|Alteromonadaceae 1236|Gammaproteobacteria M Peptidase M50 - - - ko:K16922 - - - - ko00000,ko01002 - - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 k141_32606_1 1116375.VEJY3_21711 5.6e-159 453.0 COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,1RMVU@1236|Gammaproteobacteria,1XZTY@135623|Vibrionales 135623|Vibrionales C alcohol dehydrogenase - - - - - - - - - - - - Fe-ADH k141_37378_1 1205908.AKXW01000072_gene3415 9.03e-10 60.8 COG4096@1|root,COG4096@2|Bacteria,1NUBD@1224|Proteobacteria,1SMR2@1236|Gammaproteobacteria,1XVF5@135623|Vibrionales 135623|Vibrionales V Domain of unknown function (DUF4145) - - - - - - - - - - - - DUF4145 k141_37378_3 617140.AJZE01000076_gene1293 7.19e-89 275.0 2ECI4@1|root,336GB@2|Bacteria,1NAWD@1224|Proteobacteria,1SE88@1236|Gammaproteobacteria,1XUXQ@135623|Vibrionales 135623|Vibrionales S PcfJ-like protein - - - - - - - - - - - - PcfJ k141_1735_1 1116375.VEJY3_12865 5.74e-73 228.0 COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,1RNPX@1236|Gammaproteobacteria,1XUN0@135623|Vibrionales 135623|Vibrionales P Belongs to the ABC transporter superfamily fbpC - 3.6.3.30 ko:K02010 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.10 - - ABC_tran,TOBE_2 k141_1735_2 1116375.VEJY3_12860 0.0 905.0 COG1109@1|root,COG1109@2|Bacteria,1QUGD@1224|Proteobacteria,1T1Y5@1236|Gammaproteobacteria,1XSW0@135623|Vibrionales 135623|Vibrionales G Phosphoglucomutase/phosphomannomutase, C-terminal domain - - - - - - - - - - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV k141_1735_3 223926.28807485 0.0 1662.0 COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,1RMW9@1236|Gammaproteobacteria,1XVEU@135623|Vibrionales 135623|Vibrionales G COG3459 Cellobiose phosphorylase chbP - 2.4.1.280 ko:K18675 ko00520,map00520 - R09942 RC00049 ko00000,ko00001,ko01000 - GH94 - Glyco_hydro_36,Glyco_transf_36 k141_1735_4 223926.28807484 0.0 1172.0 COG3525@1|root,COG3525@2|Bacteria,1MVDE@1224|Proteobacteria,1RMNI@1236|Gammaproteobacteria,1XTCA@135623|Vibrionales 135623|Vibrionales G Glycosyl hydrolase family 20, domain 2 exo - 3.2.1.52 ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 M00079 R00022,R06004,R11316 RC00049 ko00000,ko00001,ko00002,ko01000,ko03110 - GH20 - Glyco_hydro_20,Glyco_hydro_20b k141_1735_5 223926.28807483 2.19e-193 538.0 COG2971@1|root,COG2971@2|Bacteria,1R41I@1224|Proteobacteria,1RPMK@1236|Gammaproteobacteria,1XUVD@135623|Vibrionales 135623|Vibrionales G N-acetylglucosamine kinase gspK GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0047931 2.7.1.8 ko:K18676 ko00520,ko01100,map00520,map01100 - R01961 RC00002,RC00017 ko00000,ko00001,ko01000 - - - BcrAD_BadFG k141_1735_6 1219076.N646_1581 0.0 1013.0 COG0726@1|root,COG0726@2|Bacteria,1QXDY@1224|Proteobacteria,1T39I@1236|Gammaproteobacteria,1Y34J@135623|Vibrionales 135623|Vibrionales G Cellulase N-terminal ig-like domain - - - - - - - - - - - - CelD_N,Glyco_hydro_9 k141_1735_7 674977.VMC_24450 4.55e-240 659.0 COG4608@1|root,COG4608@2|Bacteria,1QE80@1224|Proteobacteria,1S135@1236|Gammaproteobacteria,1XSK7@135623|Vibrionales 135623|Vibrionales P Belongs to the ABC transporter superfamily - - - ko:K02032 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - ABC_tran,oligo_HPY k141_1735_8 1280001.BAOA01000059_gene2302 2.93e-234 644.0 COG0444@1|root,COG0444@2|Bacteria,1MZF6@1224|Proteobacteria,1RPET@1236|Gammaproteobacteria,1XUF0@135623|Vibrionales 135623|Vibrionales P Belongs to the ABC transporter superfamily - - - ko:K02031 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - ABC_tran,oligo_HPY k141_1735_9 223926.28807479 4.14e-232 640.0 COG1173@1|root,COG1173@2|Bacteria,1MYZ5@1224|Proteobacteria,1RRNF@1236|Gammaproteobacteria,1XT2P@135623|Vibrionales 135623|Vibrionales P COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components - - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1,OppC_N k141_1735_10 1280001.BAOA01000059_gene2300 3.55e-231 637.0 COG0601@1|root,COG0601@2|Bacteria,1NH5E@1224|Proteobacteria,1RY03@1236|Gammaproteobacteria,1XSN8@135623|Vibrionales 135623|Vibrionales P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components - - - ko:K02033 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 k141_1735_11 223926.28807477 0.0 1130.0 COG0747@1|root,COG0747@2|Bacteria,1N4PK@1224|Proteobacteria,1RZPY@1236|Gammaproteobacteria,1XV00@135623|Vibrionales 135623|Vibrionales E ABC-type dipeptide transport system, periplasmic component - - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 k141_1735_12 223926.28807476 0.0 2005.0 COG0642@1|root,COG0745@1|root,COG2770@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG2770@2|Bacteria,1NRP8@1224|Proteobacteria,1T1Y4@1236|Gammaproteobacteria,1XTDR@135623|Vibrionales 135623|Vibrionales T Histidine kinase chiS - - ko:K19694 - - - - ko00000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,PAS,PAS_8,Response_reg k141_1735_14 1116375.VEJY3_12805 1.54e-227 629.0 COG2813@1|root,COG2813@2|Bacteria,1MXE9@1224|Proteobacteria,1RQCH@1236|Gammaproteobacteria,1XUIH@135623|Vibrionales 135623|Vibrionales J Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle rsmC GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052914,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.172 ko:K00564 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - MTS,MTS_N k141_1735_15 1116375.VEJY3_12800 1.43e-233 645.0 COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,1RN5Z@1236|Gammaproteobacteria,1XT37@135623|Vibrionales 135623|Vibrionales S permease VP2476 - - - - - - - - - - - AI-2E_transport k141_1735_16 223926.28807473 2.12e-206 577.0 COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,1RM7N@1236|Gammaproteobacteria,1XUGV@135623|Vibrionales 135623|Vibrionales H Glutamate-1-semialdehyde aminotransferase hemL GO:0003674,GO:0003824,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016853,GO:0016866,GO:0016869,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 5.4.3.8 ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02272 RC00677 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 k141_35173_1 935836.JAEL01000024_gene2435 1.92e-224 630.0 COG1012@1|root,COG1012@2|Bacteria,1UHQT@1239|Firmicutes,4IS6J@91061|Bacilli,1ZSC0@1386|Bacillus 91061|Bacilli C Aldehyde dehydrogenase family - - - - - - - - - - - - Aldedh k141_35173_2 1211814.CAPG01000014_gene515 1.73e-28 103.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,4HM6R@91061|Bacilli,1ZIHJ@1386|Bacillus 91061|Bacilli CQ BMC domain - - - ko:K04027 - - - - ko00000 - - - BMC k141_17262_1 765912.Thimo_2930 1.54e-21 100.0 COG2304@1|root,COG2304@2|Bacteria,1MW51@1224|Proteobacteria,1RMD3@1236|Gammaproteobacteria,1WWHI@135613|Chromatiales 135613|Chromatiales S von Willebrand factor, type A - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - TPR_1,TPR_16,VWA_2 k141_33954_2 1453501.JELR01000002_gene613 7.6e-67 209.0 2DZ4B@1|root,34CDM@2|Bacteria,1PAEV@1224|Proteobacteria,1SV2F@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF4136) - - - - - - - - - - - - DUF4136 k141_33954_3 1279017.AQYJ01000028_gene2209 0.0 1109.0 COG3008@1|root,COG3008@2|Bacteria,1MU1T@1224|Proteobacteria,1RN89@1236|Gammaproteobacteria,46474@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Paraquat-inducible protein B yebT GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006869,GO:0008150,GO:0009987,GO:0010876,GO:0016020,GO:0016021,GO:0016043,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0033036,GO:0042597,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071840,GO:0071944,GO:0120009 - ko:K06192 - - - - ko00000 - - - MlaD k141_33954_4 1453501.JELR01000002_gene615 1.13e-96 288.0 COG2995@1|root,COG2995@2|Bacteria,1MWG1@1224|Proteobacteria,1RM9Z@1236|Gammaproteobacteria,467ES@72275|Alteromonadaceae 1236|Gammaproteobacteria S paraquat-inducible protein A yebS GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0071944 - ko:K03808 - - - - ko00000 - - - PqiA k141_12727_2 1340434.AXVA01000001_gene1148 1.64e-206 590.0 COG1263@1|root,COG2190@1|root,COG1263@2|Bacteria,COG2190@2|Bacteria,1TPJ8@1239|Firmicutes,4HA8X@91061|Bacilli,1ZAZ3@1386|Bacillus 91061|Bacilli G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific nagE - 2.7.1.193,2.7.1.199 ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 M00267,M00809 R02738,R05199 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.13,4.A.1.1.14,4.A.1.1.15,4.A.1.1.2,4.A.1.1.5,4.A.1.1.7,4.A.1.1.9 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC k141_29117_1 1453501.JELR01000001_gene1818 1.56e-54 179.0 2E80T@1|root,332F0@2|Bacteria,1N7RY@1224|Proteobacteria,1SCE8@1236|Gammaproteobacteria,467UH@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF4389) - - - - - - - - - - - - DUF4389 k141_29117_2 1279017.AQYJ01000024_gene1185 1.31e-109 323.0 COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,1RPQ7@1236|Gammaproteobacteria,464Z9@72275|Alteromonadaceae 1236|Gammaproteobacteria I Glycerol-3-phosphate dehydrogenase gpsA GO:0003674,GO:0003824,GO:0004367,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006072,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0047952,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 - R00842,R00844 RC00029 ko00000,ko00001,ko01000 - - iJN746.PP_4169,iSFV_1184.SFV_3923 NAD_Gly3P_dh_C,NAD_Gly3P_dh_N k141_36193_2 586413.CCDL010000001_gene1471 2.09e-29 108.0 COG0454@1|root,COG0456@2|Bacteria,1V88N@1239|Firmicutes,4HK32@91061|Bacilli,23MXV@182709|Oceanobacillus 91061|Bacilli K FR47-like protein - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10 k141_20767_2 656519.Halsa_0076 2.39e-30 118.0 COG3723@1|root,COG3723@2|Bacteria,1V3B6@1239|Firmicutes,24HHQ@186801|Clostridia 186801|Clostridia L Phage recombination protein Bet bet - - - - - - - - - - - RecT k141_1737_1 1267580.AF6_0718 2.79e-75 250.0 COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,4HAFP@91061|Bacilli,21V41@150247|Anoxybacillus 91061|Bacilli V AcrB/AcrD/AcrF family - - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran k141_16078_2 1279017.AQYJ01000023_gene3107 7.92e-35 127.0 COG1091@1|root,COG1091@2|Bacteria,1MUXM@1224|Proteobacteria,1RSNR@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose - - 1.1.1.133 ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777 RC00182 ko00000,ko00001,ko00002,ko01000 - - - RmlD_sub_bind k141_30212_1 1220589.CD32_17590 9.86e-27 105.0 COG1794@1|root,COG1794@2|Bacteria,1V0AM@1239|Firmicutes,4IQXB@91061|Bacilli 91061|Bacilli M Asp/Glu/Hydantoin racemase - - 5.1.1.13 ko:K01779 ko00250,ko01054,map00250,map01054 - R00491 RC00302 ko00000,ko00001,ko01000 - - - Asp_Glu_race k141_24419_1 218284.CCDN010000001_gene1145 2.69e-126 369.0 COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,4HA13@91061|Bacilli,1ZCMB@1386|Bacillus 91061|Bacilli E Aminotransferase aspB GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769,GO:0047297 2.6.1.1,2.6.1.14 ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 - R00355,R00694,R00734,R00896,R01346,R02433,R02619,R05052 RC00006,RC00025 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 k141_37379_1 1089551.KE386572_gene363 4.23e-74 244.0 COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,2TU35@28211|Alphaproteobacteria 28211|Alphaproteobacteria P cytochrome c peroxidase mauG GO:0005575,GO:0005623,GO:0042597,GO:0044464 - - - - - - - - - - CCP_MauG,Cytochrom_C k141_779_2 745411.B3C1_15237 1.63e-97 292.0 COG0693@1|root,COG0693@2|Bacteria,1MVTT@1224|Proteobacteria,1RPVK@1236|Gammaproteobacteria,1J95P@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S intracellular protease amidase - - - - - - - - - - - - DJ-1_PfpI k141_779_3 1453501.JELR01000001_gene2853 1.04e-227 640.0 COG0477@1|root,COG2814@2|Bacteria,1MVKJ@1224|Proteobacteria,1RMHJ@1236|Gammaproteobacteria,464EA@72275|Alteromonadaceae 1236|Gammaproteobacteria EGP Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family xylE GO:0003674,GO:0005215,GO:0005351,GO:0005402,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0008643,GO:0015075,GO:0015077,GO:0015078,GO:0015144,GO:0015145,GO:0015146,GO:0015148,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015519,GO:0015672,GO:0015749,GO:0015750,GO:0015753,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034219,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 - ko:K05548,ko:K08138,ko:K08139 ko04113,map04113 - - - ko00000,ko00001,ko02000 2.A.1.1,2.A.1.1.3,2.A.1.15 - iECIAI1_1343.ECIAI1_4259,iECSE_1348.ECSE_4322 Sugar_tr k141_779_4 1042377.AFPJ01000020_gene2054 3.13e-139 402.0 COG1307@1|root,COG1307@2|Bacteria,1R5M9@1224|Proteobacteria,1RZYN@1236|Gammaproteobacteria,46813@72275|Alteromonadaceae 1236|Gammaproteobacteria S Uncharacterised protein, DegV family COG1307 - - - - - - - - - - - - DegV k141_779_5 1279017.AQYJ01000021_gene2851 4.15e-209 580.0 COG0825@1|root,COG0825@2|Bacteria,1MURN@1224|Proteobacteria,1RNN8@1236|Gammaproteobacteria,4649J@72275|Alteromonadaceae 1236|Gammaproteobacteria I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA accA GO:0001676,GO:0003674,GO:0003824,GO:0003989,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009317,GO:0009329,GO:0009987,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0019752,GO:0032787,GO:0032991,GO:0042759,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576,GO:1902494,GO:1990234 2.1.3.15,6.4.1.2 ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b0185,iBWG_1329.BWG_0177,iEC55989_1330.EC55989_0179,iECDH10B_1368.ECDH10B_0165,iECDH1ME8569_1439.ECDH1ME8569_0178,iECED1_1282.ECED1_0191,iECH74115_1262.ECH74115_0195,iECIAI1_1343.ECIAI1_0185,iECNA114_1301.ECNA114_0175,iECO111_1330.ECO111_0186,iECO26_1355.ECO26_0187,iECP_1309.ECP_0193,iECSE_1348.ECSE_0184,iECSF_1327.ECSF_0200,iECSP_1301.ECSP_0184,iECW_1372.ECW_m0181,iECs_1301.ECs0187,iEKO11_1354.EKO11_3733,iEcDH1_1363.EcDH1_3418,iEcE24377_1341.EcE24377A_0189,iEcHS_1320.EcHS_A0187,iG2583_1286.G2583_0188,iJN746.PP_1607,iJO1366.b0185,iJR904.b0185,iLF82_1304.LF82_0008,iNRG857_1313.NRG857_00945,iSDY_1059.SDY_0201,iSFV_1184.SFV_0168,iSF_1195.SF0175,iSFxv_1172.SFxv_0185,iS_1188.S0178,iUMNK88_1353.UMNK88_190,iWFL_1372.ECW_m0181,iY75_1357.Y75_RS00935,iZ_1308.Z0197 ACCA k141_779_6 1279017.AQYJ01000021_gene2850 0.0 1751.0 COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,1RP0K@1236|Gammaproteobacteria,464YY@72275|Alteromonadaceae 1236|Gammaproteobacteria L DNA polymerase III alpha subunit dnaE GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon k141_27039_1 1461580.CCAS010000002_gene317 6.65e-116 337.0 COG0745@1|root,COG0745@2|Bacteria,1TPF7@1239|Firmicutes,4HA1M@91061|Bacilli,1ZBNB@1386|Bacillus 91061|Bacilli KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process spo0A GO:0000003,GO:0000156,GO:0000160,GO:0000910,GO:0003674,GO:0006355,GO:0007049,GO:0007154,GO:0007165,GO:0008150,GO:0008356,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016043,GO:0019219,GO:0019222,GO:0019954,GO:0022402,GO:0022603,GO:0022607,GO:0023052,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0032506,GO:0035556,GO:0042173,GO:0042710,GO:0043934,GO:0043937,GO:0043938,GO:0044010,GO:0044085,GO:0044764,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051171,GO:0051252,GO:0051301,GO:0051704,GO:0051716,GO:0060089,GO:0060255,GO:0065007,GO:0071840,GO:0080090,GO:0090529,GO:0090604,GO:0090606,GO:1903506,GO:2000112,GO:2001141 - ko:K07699 ko02020,ko02024,map02020,map02024 M00485 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Spo0A_C k141_11466_1 218284.CCDN010000002_gene2078 1.77e-224 628.0 COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4HC58@91061|Bacilli,1ZB1Y@1386|Bacillus 91061|Bacilli S COG0488 ATPase components of ABC transporters with duplicated ATPase domains yheS_1 - - - - - - - - - - - ABC_tran,ABC_tran_Xtn k141_33956_1 1042377.AFPJ01000043_gene857 0.000385 45.8 2DBDT@1|root,2Z8NY@2|Bacteria,1N7S2@1224|Proteobacteria,1RTZE@1236|Gammaproteobacteria,46D1R@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_20768_1 997296.PB1_03145 1.2e-40 154.0 COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,4HA3G@91061|Bacilli,1ZAVY@1386|Bacillus 91061|Bacilli T Diguanylate cyclase - - - - - - - - - - - - EAL,FIST,FIST_C,GAF_2,GGDEF,PAS,PAS_4,PAS_9,dCache_1 k141_36194_1 926569.ANT_05210 7.92e-89 281.0 COG1523@1|root,COG1523@2|Bacteria,2G86B@200795|Chloroflexi 200795|Chloroflexi G Belongs to the glycosyl hydrolase 13 family - - 3.2.1.68 ko:K01214 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R09995,R11261 - ko00000,ko00001,ko00002,ko01000 - CBM48,GH13 - Alpha-amylase,CBM_48 k141_18601_3 1116375.VEJY3_16931 3.2e-148 421.0 COG2197@1|root,COG2197@2|Bacteria,1RDI0@1224|Proteobacteria,1RS5N@1236|Gammaproteobacteria,1XU91@135623|Vibrionales 135623|Vibrionales K helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE k141_35175_3 1279017.AQYJ01000029_gene3488 3.66e-06 49.7 COG1228@1|root,COG1228@2|Bacteria,1MXXR@1224|Proteobacteria,1RRK7@1236|Gammaproteobacteria,46458@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Amidohydrolase family - - - - - - - - - - - - Amidohydro_1,Amidohydro_3 k141_32608_1 391937.NA2_15112 7.34e-37 132.0 COG3652@1|root,COG3652@2|Bacteria,1RDPI@1224|Proteobacteria,2TUSW@28211|Alphaproteobacteria,43KTZ@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Domain of unknown function (DUF4142) MA20_42090 - - ko:K08995 - - - - ko00000 - - - DUF4142 k141_11467_1 218284.CCDN010000006_gene3647 9.06e-53 174.0 COG0370@1|root,COG0370@2|Bacteria,1TQT3@1239|Firmicutes,4HAIZ@91061|Bacilli,1ZAYP@1386|Bacillus 91061|Bacilli P COG0370 Fe2 transport system protein B yvoD - - - - - - - - - - - Gate k141_11467_2 218284.CCDN010000006_gene3646 1.86e-40 138.0 COG0546@1|root,COG0546@2|Bacteria,1TPPZ@1239|Firmicutes,4HE7X@91061|Bacilli,1ZB95@1386|Bacillus 91061|Bacilli S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool ppaX GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008967,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.6.1.1 ko:K06019 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - HAD_2 k141_36195_1 384765.SIAM614_05573 3.04e-82 256.0 COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,2TRKK@28211|Alphaproteobacteria 28211|Alphaproteobacteria M mechanosensitive ion channel MA20_40450 - - - - - - - - - - - MS_channel k141_20769_1 42565.FP66_13345 2.84e-56 175.0 COG3553@1|root,COG3553@2|Bacteria,1N757@1224|Proteobacteria,1SGSY@1236|Gammaproteobacteria,1XQDT@135619|Oceanospirillales 135619|Oceanospirillales S Uncharacterized protein conserved in bacteria (DUF2218) - - - ko:K09956 - - - - ko00000 - - - DUF2218 k141_20769_2 1397528.Q671_04865 8.06e-18 81.6 COG0697@1|root,COG0697@2|Bacteria,1P3V0@1224|Proteobacteria,1S25I@1236|Gammaproteobacteria 1236|Gammaproteobacteria EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - - - - - - - - - - EamA k141_17266_1 1042377.AFPJ01000045_gene2570 8.2e-81 241.0 COG3198@1|root,COG3198@2|Bacteria 2|Bacteria S FixH ccoH - - ko:K09926 - - - - ko00000 - - - FixH k141_11468_1 218284.CCDN010000001_gene126 3.22e-36 124.0 COG3125@1|root,COG3125@2|Bacteria,1V855@1239|Firmicutes,4HJV7@91061|Bacilli,1ZH0W@1386|Bacillus 91061|Bacilli C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4 ctaF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.9.3.1 ko:K02277 ko00190,ko01100,map00190,map01100 M00155 - - ko00000,ko00001,ko00002,ko01000 3.D.4.4 - iYO844.BSU14920 COX4_pro k141_11468_2 218284.CCDN010000001_gene127 1.1e-131 374.0 COG1845@1|root,COG1845@2|Bacteria,1TQJ1@1239|Firmicutes,4HAHK@91061|Bacilli,1ZBVD@1386|Bacillus 91061|Bacilli C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3 ctaE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.9.3.1 ko:K02276 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.4,3.D.4.6 - - COX3 k141_27820_2 1348908.KI518589_gene2520 1.98e-17 87.4 COG0860@1|root,COG0860@2|Bacteria,1V3MD@1239|Firmicutes,4HHD1@91061|Bacilli,1ZBPF@1386|Bacillus 91061|Bacilli M n-acetylmuramoyl-L-alanine amidase - - 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - Amidase_3,SH3_3,SLH,SPOR k141_35176_1 1196031.ALEG01000005_gene5607 9.93e-150 423.0 COG0813@1|root,COG0813@2|Bacteria,1TQPG@1239|Firmicutes,4HADM@91061|Bacilli,1ZCBV@1386|Bacillus 91061|Bacilli F Purine nucleoside phosphorylase deoD - 2.4.2.1 ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244 RC00033,RC00063,RC00122 ko00000,ko00001,ko01000 - - - PNP_UDP_1 k141_35176_2 1408303.JNJJ01000009_gene2247 2.96e-18 75.9 2EKRV@1|root,33EFM@2|Bacteria,1VQ20@1239|Firmicutes,4HSEI@91061|Bacilli,1ZK5P@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_33958_1 1279017.AQYJ01000025_gene702 5.91e-85 279.0 COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,1RPC6@1236|Gammaproteobacteria,46518@72275|Alteromonadaceae 1236|Gammaproteobacteria L UvrD-like helicase C-terminal domain addA - - - - - - - - - - - PDDEXK_1,UvrD-helicase,UvrD_C k141_37384_1 1009370.ALO_03506 1.18e-42 148.0 COG0563@1|root,COG0563@2|Bacteria,1TP27@1239|Firmicutes,4H2UG@909932|Negativicutes 909932|Negativicutes F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism adk - 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ADK,ADK_lid k141_5546_1 1294265.JCM21738_3756 8.07e-12 63.9 COG1404@1|root,COG1404@2|Bacteria,1TQ2M@1239|Firmicutes,4HBYC@91061|Bacilli,1ZPV5@1386|Bacillus 91061|Bacilli O Belongs to the peptidase S8 family aprE GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005576,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030193,GO:0030195,GO:0032101,GO:0032102,GO:0042730,GO:0043170,GO:0044238,GO:0048519,GO:0048583,GO:0048585,GO:0050789,GO:0050818,GO:0050819,GO:0050878,GO:0051239,GO:0051241,GO:0061041,GO:0061045,GO:0065007,GO:0065008,GO:0070011,GO:0071704,GO:0080134,GO:0140096,GO:1900046,GO:1900047,GO:1901564,GO:1903034,GO:1903035 3.4.21.62 ko:K01342,ko:K13277 ko02024,map02024 - - - ko00000,ko00001,ko01000,ko01002,ko03110 - - - Inhibitor_I9,Peptidase_S8,SLH k141_5546_2 1294265.JCM21738_3755 1.47e-136 389.0 COG2356@1|root,COG2356@2|Bacteria,1V15Q@1239|Firmicutes,4HEHE@91061|Bacilli,1ZDT8@1386|Bacillus 91061|Bacilli L Endonuclease I bsn - - - - - - - - - - - Endonuclease_1 k141_22037_1 218284.CCDN010000001_gene164 5.01e-98 301.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,1ZBIW@1386|Bacillus 91061|Bacilli V COG1132 ABC-type multidrug transport system, ATPase and permease components yknV GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702 - ko:K02021,ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21 - - ABC_membrane,ABC_tran k141_37416_1 1294265.JCM21738_1698 2.41e-146 424.0 COG0768@1|root,COG0768@2|Bacteria,1TQHY@1239|Firmicutes,4HAFX@91061|Bacilli,1ZBJM@1386|Bacillus 91061|Bacilli M penicillin-binding protein pbpA - - ko:K21465 ko00550,map00550 - - - ko00000,ko00001,ko01011 - - - PBP_dimer,Transpeptidase k141_12748_1 545693.BMQ_5248 8.72e-179 514.0 COG3211@1|root,COG3211@2|Bacteria,1UYPE@1239|Firmicutes,4HCRC@91061|Bacilli,1ZDBG@1386|Bacillus 91061|Bacilli N Bacterial protein of unknown function (DUF839) - - - ko:K07093 - - - - ko00000 - - - DUF839 k141_25760_2 398511.BpOF4_16250 2.15e-25 99.4 COG0110@1|root,COG0110@2|Bacteria,1TQEX@1239|Firmicutes,4HAJ0@91061|Bacilli,1ZDPK@1386|Bacillus 91061|Bacilli S COG0110 Acetyltransferase (isoleucine patch superfamily) maa - 2.3.1.79 ko:K00661 - - - - ko00000,ko01000 - - - CM_2,Hexapep,Hexapep_2,Mac k141_27074_2 218284.CCDN010000001_gene150 1.28e-30 115.0 COG0726@1|root,COG0726@2|Bacteria,1TS3D@1239|Firmicutes,4HAVF@91061|Bacilli,1ZC37@1386|Bacillus 91061|Bacilli G Polysaccharide deacetylase pdaA_2 - 3.5.1.104 ko:K01567,ko:K22278 - - - - ko00000,ko01000 - - - Polysacc_deac_1 k141_32637_1 218284.CCDN010000001_gene1333 5.39e-24 91.7 29S7X@1|root,30DCE@2|Bacteria,1UB4X@1239|Firmicutes,4IMHG@91061|Bacilli,1ZK60@1386|Bacillus 91061|Bacilli S Sporulation inhibitor A - - - - - - - - - - - - Sda k141_29135_1 1117379.BABA_13972 1.95e-54 182.0 COG1167@1|root,COG1167@2|Bacteria,1TPS5@1239|Firmicutes,4HB1C@91061|Bacilli,1ZASA@1386|Bacillus 91061|Bacilli K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs - - - ko:K18907 - M00700,M00702 - - ko00000,ko00002,ko01504,ko03000 - - - Aminotran_1_2,GntR k141_29135_2 1227360.C176_18517 1.15e-16 75.9 COG1279@1|root,COG1279@2|Bacteria,1V1Q2@1239|Firmicutes,4HFYS@91061|Bacilli,26F81@186818|Planococcaceae 91061|Bacilli S LysE type translocator argO - - ko:K06895 - - - - ko00000,ko02000 2.A.75.1 - - LysE k141_33984_1 1461580.CCAS010000008_gene1211 4.66e-111 332.0 COG3039@1|root,COG3039@2|Bacteria,1TPFS@1239|Firmicutes,4HD09@91061|Bacilli,1ZEKY@1386|Bacillus 91061|Bacilli L COG3039 Transposase and inactivated derivatives, IS5 family - - - - - - - - - - - - DDE_Tnp_1,DDE_Tnp_1_6,DUF772 k141_37417_1 641107.CDLVIII_1027 7.09e-21 94.0 COG1319@1|root,COG1319@2|Bacteria,1TQA5@1239|Firmicutes,248WI@186801|Clostridia,36DQR@31979|Clostridiaceae 186801|Clostridia C Molybdopterin dehydrogenase - - 1.2.5.3 ko:K03519 - - R11168 RC02800 ko00000,ko01000 - - iHN637.CLJU_RS14760 CO_deh_flav_C,FAD_binding_5 k141_13935_1 945543.VIBR0546_10889 1.15e-64 207.0 COG1749@1|root,COG1749@2|Bacteria,1MU5J@1224|Proteobacteria,1RMWX@1236|Gammaproteobacteria,1XV3D@135623|Vibrionales 135623|Vibrionales N Flagellar hook protein FlgE flgE - - ko:K02390 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FlaE,Flg_bb_rod,Flg_bbr_C k141_13935_2 675814.VIC_004755 3.04e-137 392.0 COG4787@1|root,COG4787@2|Bacteria,1RB11@1224|Proteobacteria,1S20E@1236|Gammaproteobacteria,1XVMK@135623|Vibrionales 135623|Vibrionales N flagellar basal body - - - ko:K02391 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C k141_13935_3 1280001.BAOA01000050_gene1428 1.03e-169 476.0 COG4786@1|root,COG4786@2|Bacteria,1MVMA@1224|Proteobacteria,1RMJ2@1236|Gammaproteobacteria,1XTV1@135623|Vibrionales 135623|Vibrionales N Belongs to the flagella basal body rod proteins family - - - ko:K02392 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C k141_13935_4 945543.VIBR0546_10874 5.56e-126 362.0 COG2063@1|root,COG2063@2|Bacteria,1RDEY@1224|Proteobacteria,1S2XK@1236|Gammaproteobacteria,1XVDX@135623|Vibrionales 135623|Vibrionales N Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation - - - ko:K02393 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FlgH k141_13935_5 945543.VIBR0546_10869 8.67e-207 580.0 COG1706@1|root,COG1706@2|Bacteria,1MVKW@1224|Proteobacteria,1RMRB@1236|Gammaproteobacteria,1XUVU@135623|Vibrionales 135623|Vibrionales N Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation flgI1 - - ko:K02394 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FlgI k141_13935_6 675814.VIC_004751 1.82e-59 190.0 COG3951@1|root,COG3951@2|Bacteria,1NFEC@1224|Proteobacteria,1SEGF@1236|Gammaproteobacteria,1XWX1@135623|Vibrionales 135623|Vibrionales N flagellar protein - - - ko:K02395 - - - - ko00000,ko02035 - - - Rod-binding k141_13935_7 1280001.BAOA01000050_gene1424 1.06e-230 646.0 COG1256@1|root,COG1256@2|Bacteria,1MV2M@1224|Proteobacteria,1RMEA@1236|Gammaproteobacteria,1XT20@135623|Vibrionales 135623|Vibrionales N flagellar hook-associated protein flgK - - ko:K02396 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C k141_13935_8 1517681.HW45_18490 3.8e-161 457.0 COG1344@1|root,COG1344@2|Bacteria,1PJUJ@1224|Proteobacteria,1RPNR@1236|Gammaproteobacteria,1XUAC@135623|Vibrionales 135623|Vibrionales N Bacterial flagellin N-terminal helical region flgL - - ko:K02397 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flagellin_N k141_13935_9 674977.VMC_36150 9.02e-144 417.0 COG2604@1|root,COG2604@2|Bacteria,1NNJY@1224|Proteobacteria,1SI36@1236|Gammaproteobacteria,1XWMN@135623|Vibrionales 135623|Vibrionales N Protein of unknown function DUF115 - - - - - - - - - - - - - k141_13935_10 1116375.VEJY3_23496 3.63e-44 143.0 COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1S9KC@1236|Gammaproteobacteria 1236|Gammaproteobacteria K 'Cold-shock' DNA-binding domain cspA - - ko:K03704 - - - - ko00000,ko03000 - - - CSD k141_12894_1 1294265.JCM21738_2797 3.87e-114 342.0 COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,1TQ33@1239|Firmicutes,4HAI2@91061|Bacilli,1ZB3A@1386|Bacillus 91061|Bacilli L COG1796 DNA polymerase IV (family X) polX - - ko:K02347 - - - - ko00000,ko03400 - - - DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8,PHP k141_3167_1 1453501.JELR01000001_gene2308 4.91e-60 205.0 COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,1RM9A@1236|Gammaproteobacteria,4647U@72275|Alteromonadaceae 1236|Gammaproteobacteria D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins ftsK GO:0000920,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006950,GO:0006970,GO:0007059,GO:0008094,GO:0008150,GO:0009628,GO:0009651,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0015616,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0033676,GO:0042221,GO:0042623,GO:0042802,GO:0043085,GO:0043565,GO:0044093,GO:0044425,GO:0044459,GO:0044464,GO:0045893,GO:0045935,GO:0046677,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051301,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0070887,GO:0071236,GO:0071944,GO:0080090,GO:0097159,GO:0140097,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma k141_14251_2 218284.CCDN010000001_gene967 3.48e-114 339.0 COG1570@1|root,COG1570@2|Bacteria,1TP4E@1239|Firmicutes,4HAN2@91061|Bacilli,1ZB5Q@1386|Bacillus 91061|Bacilli L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseA - 3.1.11.6 ko:K03601 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_L,tRNA_anti_2 k141_16281_1 283942.IL1586 5.23e-86 262.0 COG0491@1|root,COG0491@2|Bacteria,1PBS8@1224|Proteobacteria,1RS4P@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B k141_20944_2 545264.KB898744_gene2005 7.2e-35 134.0 COG4425@1|root,COG4425@2|Bacteria,1MXSU@1224|Proteobacteria,1RYFH@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Alpha/beta-hydrolase family N-terminus - - - - - - - - - - - - Abhydrolase_9,Abhydrolase_9_N k141_11729_2 1051646.VITU9109_19055 5.6e-66 210.0 COG0775@1|root,COG0775@2|Bacteria,1R441@1224|Proteobacteria,1S7QP@1236|Gammaproteobacteria 1236|Gammaproteobacteria F SEFIR domain - - - - - - - - - - - - SEFIR k141_19956_2 1144325.PMI22_01314 2.66e-84 261.0 COG0654@1|root,COG0654@2|Bacteria,1RESU@1224|Proteobacteria 1224|Proteobacteria CH FAD binding domain - - 1.14.13.114 ko:K14974 ko00760,ko01120,map00760,map01120 M00622 R08764 RC00115 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_3 k141_6955_1 218284.CCDN010000002_gene2239 1.96e-108 325.0 COG1966@1|root,COG1966@2|Bacteria,1TQN8@1239|Firmicutes,4H9SU@91061|Bacilli,1ZC6K@1386|Bacillus 91061|Bacilli T Carbon starvation protein cstA - - - - - - - - - - - CstA,CstA_5TM k141_9370_1 1121374.KB891585_gene1860 2.88e-51 166.0 COG1432@1|root,COG1432@2|Bacteria,1MX5C@1224|Proteobacteria,1RSP8@1236|Gammaproteobacteria 1236|Gammaproteobacteria T OST-HTH/LOTUS domain - - - - - - - - - - - - NYN,OST-HTH k141_27999_2 1280682.AUKA01000016_gene2176 3.26e-10 62.0 COG0558@1|root,COG0558@2|Bacteria,1V6PJ@1239|Firmicutes,24J7Y@186801|Clostridia,4BW93@830|Butyrivibrio 186801|Clostridia I CDP-alcohol phosphatidyltransferase pgsA - 2.7.8.41,2.7.8.5 ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 - R01801,R02030 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 - - - CDP-OH_P_transf k141_34188_1 218284.CCDN010000001_gene1805 3.53e-72 225.0 COG0500@1|root,COG2226@2|Bacteria,1UPKF@1239|Firmicutes,4HEP0@91061|Bacilli,1ZCPU@1386|Bacillus 91061|Bacilli Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_23,Methyltransf_25 k141_23707_1 1279017.AQYJ01000024_gene1148 2.74e-133 394.0 COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RQTU@1236|Gammaproteobacteria,465ST@72275|Alteromonadaceae 1236|Gammaproteobacteria C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family merA - - - - - - - - - - - Pyr_redox_2,Pyr_redox_dim,SNARE_assoc k141_18990_1 1307436.PBF_00515 9.68e-70 216.0 COG3842@1|root,COG3842@2|Bacteria,1TS7K@1239|Firmicutes,4HA0K@91061|Bacilli,1ZC1M@1386|Bacillus 91061|Bacilli E ATPases associated with a variety of cellular activities - - 3.6.3.30 ko:K02010 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.10 - - ABC_tran k141_18990_2 1307436.PBF_00510 6.42e-31 119.0 COG1178@1|root,COG1178@2|Bacteria,1TPMX@1239|Firmicutes,4HBPX@91061|Bacilli,1ZQES@1386|Bacillus 91061|Bacilli P Binding-protein-dependent transport system inner membrane component - - - ko:K02011 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - BPD_transp_1 k141_4377_1 218284.CCDN010000001_gene69 2.58e-97 288.0 COG2302@1|root,COG2302@2|Bacteria,1U5V2@1239|Firmicutes,4HD3F@91061|Bacilli,1ZC97@1386|Bacillus 91061|Bacilli S conserved protein, contains S4-like domain ylmH - - - - - - - - - - - S4 k141_19957_2 439481.Aboo_0320 1.02e-17 84.3 COG1042@1|root,arCOG01338@2157|Archaea,arCOG01340@2157|Archaea,2XT9G@28890|Euryarchaeota,3F2GC@33867|unclassified Euryarchaeota 28890|Euryarchaeota C TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain - - 6.2.1.13 ko:K01905,ko:K22224 ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120 - R00229,R00920 RC00004,RC00012,RC00014 ko00000,ko00001,ko01000,ko01004 - - - ATP-grasp_5,CoA_binding_2,Succ_CoA_lig k141_24682_1 1294265.JCM21738_5425 1.12e-188 544.0 COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H9SA@91061|Bacilli,1ZAXY@1386|Bacillus 91061|Bacilli M penicillin-binding protein - - 2.4.1.129,3.4.16.4 ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase k141_6957_2 1132442.KB889752_gene2618 1.89e-46 155.0 COG5513@1|root,COG5513@2|Bacteria,1V4PH@1239|Firmicutes,4HG7Y@91061|Bacilli,1ZG3W@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3298) - - - - - - - - - - - - DUF3298,DUF4163 k141_4378_1 866895.HBHAL_1734 2.86e-79 248.0 COG2124@1|root,COG2124@2|Bacteria,1TP02@1239|Firmicutes,4HAIY@91061|Bacilli,3NFVQ@45667|Halobacillus 91061|Bacilli Q Cytochrome P450 cypC - 1.11.2.4 ko:K15629 - - R09740 - ko00000,ko00199,ko01000 - - - p450 k141_23708_1 1294265.JCM21738_2622 1.58e-132 378.0 COG4549@1|root,COG4549@2|Bacteria,1V509@1239|Firmicutes,4HH2V@91061|Bacilli,1ZGDU@1386|Bacillus 91061|Bacilli S protein conserved in bacteria ycnI - - - - - - - - - - - DUF1775 k141_23708_2 1294265.JCM21738_2618 6.01e-11 57.4 29S6V@1|root,30DBC@2|Bacteria,1UB3T@1239|Firmicutes,4IMGE@91061|Bacilli,1ZK3N@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_34189_1 218284.CCDN010000001_gene150 5.76e-97 290.0 COG0726@1|root,COG0726@2|Bacteria,1TS3D@1239|Firmicutes,4HAVF@91061|Bacilli,1ZC37@1386|Bacillus 91061|Bacilli G Polysaccharide deacetylase pdaA_2 - 3.5.1.104 ko:K01567,ko:K22278 - - - - ko00000,ko01000 - - - Polysacc_deac_1 k141_6958_2 1123033.ARNF01000042_gene1513 4.92e-15 77.0 COG1266@1|root,COG1266@2|Bacteria,1QPQ0@1224|Proteobacteria,1S8GA@1236|Gammaproteobacteria,3NNXK@468|Moraxellaceae 1236|Gammaproteobacteria S CAAX protease self-immunity - - - ko:K07052 - - - - ko00000 - - - Abi k141_5735_3 1220589.CD32_16065 3.6e-24 102.0 COG0553@1|root,COG4715@1|root,COG0553@2|Bacteria,COG4715@2|Bacteria,1TPFZ@1239|Firmicutes,4HAIF@91061|Bacilli,3IXR5@400634|Lysinibacillus 91061|Bacilli KL Helicase SNF snf - - - - - - - - - - - Helicase_C,SNF2_N,SNF2_assoc,SWIM k141_11730_2 1123229.AUBC01000006_gene952 4.23e-18 80.9 COG3474@1|root,COG3474@2|Bacteria,1N6WA@1224|Proteobacteria,2UHTC@28211|Alphaproteobacteria,3K0DY@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C cytochrome - - - - - - - - - - - - - k141_11730_3 223926.28809511 3.79e-227 634.0 COG2041@1|root,COG2041@2|Bacteria,1MX9E@1224|Proteobacteria,1RP2M@1236|Gammaproteobacteria,1XW26@135623|Vibrionales 135623|Vibrionales S Mo-co oxidoreductase dimerisation domain - - - - - - - - - - - - Mo-co_dimer,Oxidored_molyb k141_12911_1 861299.J421_1491 2.32e-99 308.0 COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,1ZSZ7@142182|Gemmatimonadetes 142182|Gemmatimonadetes CE Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - - - - - - - - - - Fer4_20,Fer4_7,Pyr_redox_2,Pyr_redox_3 k141_15069_1 1144342.PMI40_04215 9.43e-77 250.0 COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,2VJUZ@28216|Betaproteobacteria,478HY@75682|Oxalobacteraceae 28216|Betaproteobacteria EQ Hydantoinase/oxoprolinase N-terminal region - - 3.5.2.14 ko:K01473 ko00330,ko01100,map00330,map01100 - R03187 RC00632 ko00000,ko00001,ko01000 - - - Hydant_A_N,Hydantoinase_A k141_3185_1 595537.Varpa_1837 5.61e-13 70.9 COG4627@1|root,COG4627@2|Bacteria,1MWG7@1224|Proteobacteria 1224|Proteobacteria M transferase activity, transferring glycosyl groups - - - - - - - - - - - - Glycos_transf_1 k141_3185_2 1535422.ND16A_1853 1.93e-25 106.0 COG3104@1|root,COG3104@2|Bacteria,1QUVH@1224|Proteobacteria,1T22D@1236|Gammaproteobacteria,2Q7PA@267889|Colwelliaceae 1236|Gammaproteobacteria E Major Facilitator Superfamily - - - - - - - - - - - - MFS_1,MFS_3 k141_23710_1 223926.28807889 7.93e-192 541.0 COG1027@1|root,COG1027@2|Bacteria,1R9JY@1224|Proteobacteria,1RP5Z@1236|Gammaproteobacteria,1XSMK@135623|Vibrionales 135623|Vibrionales E Aspartate ammonia-lyase aspA - 4.3.1.1 ko:K01744 ko00250,ko01100,map00250,map01100 - R00490 RC00316,RC02799 ko00000,ko00001,ko01000 - - - FumaraseC_C,Lyase_1 k141_10448_1 218284.CCDN010000006_gene3540 2.66e-178 508.0 COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,4HBVK@91061|Bacilli,1ZBPB@1386|Bacillus 91061|Bacilli L DEAD DEAH box helicase deaD3 - 3.6.4.13 ko:K05592 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,Helicase_C k141_37574_1 1430331.EP10_06985 3.57e-83 265.0 COG1075@1|root,COG1075@2|Bacteria,1UC87@1239|Firmicutes,4HFBV@91061|Bacilli,1WF2I@129337|Geobacillus 91061|Bacilli S acetyltransferases and hydrolases with the alpha beta hydrolase fold - - 3.1.1.3 ko:K01046 ko00561,ko01100,map00561,map01100 M00098 R02250,R02687 RC00020,RC00037,RC00041,RC00094 ko00000,ko00001,ko00002,ko01000 - - - DUF676,YSIRK_signal k141_14259_1 203122.Sde_2844 4.84e-44 162.0 COG4676@1|root,COG4676@2|Bacteria,1NZI5@1224|Proteobacteria,1RP4G@1236|Gammaproteobacteria,466MN@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein conserved in bacteria - - - - - - - - - - - - CarboxypepD_reg k141_14259_2 1116375.VEJY3_14435 2.59e-188 532.0 COG4942@1|root,COG4942@2|Bacteria,1MY3E@1224|Proteobacteria,1RPQP@1236|Gammaproteobacteria,1XSXQ@135623|Vibrionales 135623|Vibrionales D COG4942 Membrane-bound metallopeptidase envC - - - - - - - - - - - Peptidase_M23 k141_14259_3 1280001.BAOA01000011_gene4281 2.3e-188 524.0 COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,1RNCA@1236|Gammaproteobacteria,1XTF9@135623|Vibrionales 135623|Vibrionales E Serine acetyltransferase cysE - 2.3.1.30 ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 M00021 R00586 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,SATase_N k141_14259_4 223926.28807858 8.73e-236 650.0 COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,1RPQ7@1236|Gammaproteobacteria,1XSBF@135623|Vibrionales 135623|Vibrionales I Glycerol-3-phosphate dehydrogenase gpsA GO:0003674,GO:0003824,GO:0004367,GO:0006072,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 - R00842,R00844 RC00029 ko00000,ko00001,ko01000 - - - NAD_Gly3P_dh_C,NAD_Gly3P_dh_N k141_22363_1 42565.FP66_13035 3.74e-123 357.0 COG0604@1|root,COG0604@2|Bacteria,1MWBD@1224|Proteobacteria,1RPCQ@1236|Gammaproteobacteria,1XK06@135619|Oceanospirillales 135619|Oceanospirillales C Quinone oxidoreductase - - 1.6.5.5 ko:K00344 - - - - ko00000,ko01000 - - - ADH_N,ADH_zinc_N k141_35451_1 1279017.AQYJ01000028_gene2396 1.55e-106 316.0 COG0611@1|root,COG0611@2|Bacteria,1MU9X@1224|Proteobacteria,1RNHU@1236|Gammaproteobacteria,466CJ@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 thiL GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009030,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009229,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042357,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.16 ko:K00946 ko00730,ko01100,map00730,map01100 M00127 R00617 RC00002 ko00000,ko00001,ko00002,ko01000 - - iSFV_1184.SFV_0382 AIRS,AIRS_C k141_35451_2 1279017.AQYJ01000028_gene2395 2e-86 256.0 COG0781@1|root,COG0781@2|Bacteria,1RHFZ@1224|Proteobacteria,1S6AJ@1236|Gammaproteobacteria,467Y1@72275|Alteromonadaceae 1236|Gammaproteobacteria K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons nusB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - ko:K03625 - - - - ko00000,ko03009,ko03021 - - - NusB k141_12912_1 756499.Desde_2129 2.06e-07 51.2 COG1028@1|root,COG1028@2|Bacteria,1TSND@1239|Firmicutes,24BVM@186801|Clostridia,264PP@186807|Peptococcaceae 186801|Clostridia IQ Enoyl-(Acyl carrier protein) reductase - - - - - - - - - - - - adh_short,adh_short_C2 k141_12912_2 1227360.C176_13872 2.37e-43 147.0 COG1309@1|root,COG1309@2|Bacteria,1V45P@1239|Firmicutes,4HHJU@91061|Bacilli,26FEA@186818|Planococcaceae 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - TetR_C_8,TetR_N k141_29352_2 1042377.AFPJ01000008_gene1994 1.63e-290 800.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,469E3@72275|Alteromonadaceae 1236|Gammaproteobacteria C Aldehyde dehydrogenase family - - 1.2.1.39 ko:K00146 ko00360,ko00643,ko01100,ko01120,map00360,map00643,map01100,map01120 - R02536 RC00080 ko00000,ko00001,ko01000 - - - Aldedh k141_29352_3 1042377.AFPJ01000008_gene1995 1.1e-106 315.0 COG2267@1|root,COG2267@2|Bacteria 2|Bacteria I carboxylic ester hydrolase activity - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 k141_29352_4 1042377.AFPJ01000008_gene1996 2.15e-103 302.0 COG1335@1|root,COG1335@2|Bacteria,1NZJ1@1224|Proteobacteria,1SA73@1236|Gammaproteobacteria,46APU@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Isochorismatase family - - 3.5.1.107 ko:K13995 ko00760,ko01120,map00760,map01120 M00622 R03540 RC00950 ko00000,ko00001,ko00002,ko01000 - - - Isochorismatase k141_29352_5 1042377.AFPJ01000008_gene1997 1.97e-248 687.0 COG0654@1|root,COG0654@2|Bacteria,1MUN4@1224|Proteobacteria,1RRWV@1236|Gammaproteobacteria,46B6K@72275|Alteromonadaceae 1236|Gammaproteobacteria CH COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - 1.14.13.127,1.14.13.20 ko:K05712,ko:K10676 ko00360,ko00361,ko01100,ko01120,ko01220,map00360,map00361,map01100,map01120,map01220 M00545 R03997,R05441,R06786,R06787 RC00046,RC00236 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_3 k141_29352_6 1042377.AFPJ01000008_gene1998 1.51e-195 542.0 COG3473@1|root,COG3473@2|Bacteria 2|Bacteria Q Maleate cis-trans isomerase - - 5.2.1.1 ko:K01799 ko00650,ko00760,ko01120,map00650,map00760,map01120 M00622 R01087 RC00448 ko00000,ko00001,ko00002,ko01000 - - - Asp_Glu_race k141_29352_7 1042377.AFPJ01000008_gene1999 2.56e-218 610.0 COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,1RYB9@1236|Gammaproteobacteria,467YJ@72275|Alteromonadaceae 1236|Gammaproteobacteria EGP Sugar (and other) transporter tetA - - ko:K08151 - M00668 - - ko00000,ko00002,ko01504,ko02000 2.A.1.2.38,2.A.1.2.39,2.A.1.2.4,2.A.1.2.41,2.A.1.2.68,2.A.1.2.75 - - MFS_1,Sugar_tr k141_29352_8 1042377.AFPJ01000008_gene2000 3.96e-177 494.0 COG3473@1|root,COG3473@2|Bacteria,1RB05@1224|Proteobacteria,1S5KQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q Asp Glu racemase - - 5.2.1.1 ko:K01799 ko00650,ko00760,ko01120,map00650,map00760,map01120 M00622 R01087 RC00448 ko00000,ko00001,ko00002,ko01000 - - - Asp_Glu_race k141_29352_9 247634.GPB2148_1462 4.33e-267 772.0 COG4774@1|root,COG4774@2|Bacteria,1QNP7@1224|Proteobacteria,1RZ67@1236|Gammaproteobacteria 1236|Gammaproteobacteria P TonB-dependent receptor plug - - - - - - - - - - - - Plug,TonB_dep_Rec k141_24685_1 1294265.JCM21738_260 7.25e-136 406.0 COG1196@1|root,COG1196@2|Bacteria,1TPJV@1239|Firmicutes,4HB89@91061|Bacilli,1ZAWM@1386|Bacillus 91061|Bacilli D Required for chromosome condensation and partitioning smc GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K03529 - - - - ko00000,ko03036 - - - SMC_N,SMC_hinge k141_6960_1 1279017.AQYJ01000029_gene3795 1.66e-223 638.0 COG3227@1|root,COG3227@2|Bacteria,1P416@1224|Proteobacteria,1RR7I@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Zinc metalloprotease (Elastase) nprV GO:0005575,GO:0005576,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0009405,GO:0019538,GO:0043170,GO:0044238,GO:0044419,GO:0051704,GO:0071704,GO:1901564 3.4.24.25,3.4.24.26 ko:K01399,ko:K08604 ko01503,ko02024,ko05110,ko05111,map01503,map02024,map05110,map05111 - - - ko00000,ko00001,ko01000,ko01002 - - - FTP,PPC,P_proprotein,PepSY,Peptidase_M4,Peptidase_M4_C k141_9371_1 1042377.AFPJ01000009_gene326 9.4e-128 372.0 COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RNN0@1236|Gammaproteobacteria,467I6@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0436 Aspartate tyrosine aromatic aminotransferase aspC - 2.6.1.1,2.6.1.84 ko:K00812,ko:K12252 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 - R00355,R00694,R00734,R00896,R02433,R02619,R05052,R08197 RC00006,RC00008 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 k141_9371_2 1042377.AFPJ01000009_gene325 2.1e-149 436.0 COG1757@1|root,COG1757@2|Bacteria,1MVDF@1224|Proteobacteria,1RS40@1236|Gammaproteobacteria,464WZ@72275|Alteromonadaceae 1236|Gammaproteobacteria C Na H antiporter nhaC - - ko:K03315 - - - - ko00000,ko02000 2.A.35 - - Na_H_antiporter k141_5737_1 218284.CCDN010000004_gene3048 5.65e-73 228.0 COG1252@1|root,COG1252@2|Bacteria,1TTBR@1239|Firmicutes,4HDJK@91061|Bacilli,1ZFJZ@1386|Bacillus 91061|Bacilli C Pyridine nucleotide-disulphide oxidoreductase - - - - - - - - - - - - Pyr_redox_2 k141_15070_1 1116375.VEJY3_22336 4.64e-191 534.0 COG4948@1|root,COG4948@2|Bacteria,1MW76@1224|Proteobacteria,1RMKS@1236|Gammaproteobacteria,1XUBP@135623|Vibrionales 135623|Vibrionales M Belongs to the mandelate racemase muconate lactonizing enzyme family - - 5.1.1.20 ko:K19802 - - R10938 RC03309 ko00000,ko01000 - - - MR_MLE_C,MR_MLE_N k141_16302_1 247490.KSU1_D0839 0.000904 45.8 COG2353@1|root,COG2353@2|Bacteria,2J1I0@203682|Planctomycetes 203682|Planctomycetes S YceI-like domain - - - - - - - - - - - - YceI k141_36356_1 1131730.BAVI_22728 1.81e-16 77.8 COG0644@1|root,COG0644@2|Bacteria,1TRRU@1239|Firmicutes,4HBFQ@91061|Bacilli,1ZASH@1386|Bacillus 91061|Bacilli C COG0644 Dehydrogenases (flavoproteins) - - - ko:K00313 - - - - ko00000,ko01000 - - - DAO,FAD_binding_3,FAD_oxidored,HI0933_like,Trp_halogenase k141_36356_2 1131730.BAVI_22733 2.77e-69 208.0 COG2440@1|root,COG2440@2|Bacteria,1V6DH@1239|Firmicutes,4HII2@91061|Bacilli,1ZHB9@1386|Bacillus 91061|Bacilli C COG2440 Ferredoxin-like protein - - - ko:K03855 - - - - ko00000 - - - ETF_QO k141_11748_2 388051.AUFE01000003_gene758 2.97e-137 398.0 COG0583@1|root,COG0583@2|Bacteria,1N663@1224|Proteobacteria,2W9HC@28216|Betaproteobacteria,1KCIB@119060|Burkholderiaceae 28216|Betaproteobacteria K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate k141_35471_1 1499680.CCFE01000011_gene604 5.27e-120 359.0 COG1053@1|root,COG1053@2|Bacteria,1TPAR@1239|Firmicutes,4HBVG@91061|Bacilli,1ZM9P@1386|Bacillus 91061|Bacilli C Fumarate reductase flavoprotein C-term sdhA - 1.3.5.1,1.3.5.4 ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C k141_22391_1 1294265.JCM21738_1758 1.08e-135 386.0 COG1994@1|root,COG1994@2|Bacteria,1V6D4@1239|Firmicutes,4H9SF@91061|Bacilli,1ZCSE@1386|Bacillus 91061|Bacilli S Peptidase M50 ywhC - - - - - - - - - - - Peptidase_M50 k141_22391_2 997296.PB1_07887 6.69e-61 190.0 28J0N@1|root,2Z8XT@2|Bacteria,1V1UK@1239|Firmicutes,4HD4W@91061|Bacilli,1ZBQ1@1386|Bacillus 91061|Bacilli S YwhD family ywhD - - - - - - - - - - - YwhD k141_12924_1 42565.FP66_03500 7.36e-43 149.0 COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,1RNCK@1236|Gammaproteobacteria,1XH97@135619|Oceanospirillales 135619|Oceanospirillales Q Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - - - - - - - - - - DctP k141_16323_1 1294265.JCM21738_1936 8.76e-184 513.0 COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4H9PZ@91061|Bacilli,1ZC9B@1386|Bacillus 91061|Bacilli EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components oppC - - ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - BPD_transp_1,OppC_N k141_16323_2 1294265.JCM21738_1935 1.12e-101 297.0 COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,4HA4E@91061|Bacilli,1ZB72@1386|Bacillus 91061|Bacilli P Belongs to the ABC transporter superfamily oppD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY k141_3198_1 218284.CCDN010000002_gene2938 4.01e-172 495.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,1ZAY7@1386|Bacillus 91061|Bacilli V ABC transporter ygaD GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702 - ko:K11085 ko02010,map02010 - - - ko00000,ko00001,ko01000,ko02000 3.A.1.106 - - ABC_membrane,ABC_tran k141_30376_1 1453501.JELR01000002_gene1301 6.61e-102 299.0 COG3108@1|root,COG3108@2|Bacteria,1NDQH@1224|Proteobacteria,1T130@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Peptidase M15 - - - - - - - - - - - - Peptidase_M15_3 k141_22392_1 218284.CCDN010000002_gene2700 4.79e-97 283.0 COG3708@1|root,COG3708@2|Bacteria,1V5YN@1239|Firmicutes,4HHBJ@91061|Bacilli,1ZKQ3@1386|Bacillus 91061|Bacilli K Bacterial transcription activator, effector binding domain - - - ko:K13653 - - - - ko00000,ko03000 - - - GyrI-like k141_4391_1 1294265.JCM21738_669 4.75e-156 446.0 COG1219@1|root,COG1219@2|Bacteria,1TQ00@1239|Firmicutes,4H9U4@91061|Bacilli,1ZANE@1386|Bacillus 91061|Bacilli O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP clpX GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - ko:K03544 ko04112,map04112 - - - ko00000,ko00001,ko03110 - - - AAA_2,ClpB_D2-small,zf-C4_ClpX k141_35472_1 1279017.AQYJ01000028_gene2171 2.07e-132 378.0 COG0560@1|root,COG0560@2|Bacteria,1RA1A@1224|Proteobacteria,1S21J@1236|Gammaproteobacteria,466GA@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0560 Phosphoserine phosphatase - - - - - - - - - - - - HAD k141_37593_1 1479235.KK366039_gene1300 2.62e-162 461.0 COG0656@1|root,COG0656@2|Bacteria,1MX6S@1224|Proteobacteria,1RQA1@1236|Gammaproteobacteria,1XNFI@135619|Oceanospirillales 135619|Oceanospirillales S Aldo/keto reductase family - - - - - - - - - - - - Aldo_ket_red k141_37593_2 1504981.KO116_2900 1.34e-75 235.0 2CDHC@1|root,32RXT@2|Bacteria,1N2M3@1224|Proteobacteria,1S6Z6@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_37593_3 1122134.KB893651_gene2010 1.84e-61 192.0 2CNK3@1|root,31TH7@2|Bacteria,1R38H@1224|Proteobacteria,1S7X7@1236|Gammaproteobacteria,1XKY6@135619|Oceanospirillales 135619|Oceanospirillales S Protein of Unknown function (DUF2784) - - - - - - - - - - - - DUF2784 k141_37593_4 765913.ThidrDRAFT_3254 1.29e-82 268.0 COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,1RNA5@1236|Gammaproteobacteria,1WWMA@135613|Chromatiales 135613|Chromatiales P Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity katG - 1.11.1.21 ko:K03782 ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110 - R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906 RC00034,RC00213,RC00767,RC02141 ko00000,ko00001,ko01000 - - - peroxidase k141_24707_1 1116375.VEJY3_07385 0.0 972.0 COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1RR19@1236|Gammaproteobacteria,1XT8G@135623|Vibrionales 135623|Vibrionales T COG0642 Signal transduction histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,Response_reg k141_24707_2 1116375.VEJY3_07380 3.76e-252 695.0 COG3287@1|root,COG3287@2|Bacteria,1R474@1224|Proteobacteria,1SYIE@1236|Gammaproteobacteria,1XSD1@135623|Vibrionales 135623|Vibrionales S FIST N domain - - - - - - - - - - - - FIST,FIST_C k141_24707_3 1116375.VEJY3_07375 5.03e-48 156.0 2AWW7@1|root,31NTM@2|Bacteria,1QKHM@1224|Proteobacteria,1TIMS@1236|Gammaproteobacteria,1XZCI@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_24707_4 674977.VMC_38650 0.0 957.0 COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,1RM7I@1236|Gammaproteobacteria,1XT6K@135623|Vibrionales 135623|Vibrionales C Belongs to the heme-copper respiratory oxidase family ccoN - 1.9.3.1 ko:K00404 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - COX1 k141_24707_5 1219076.N646_0593 1.65e-150 422.0 COG2993@1|root,COG2993@2|Bacteria,1MXEY@1224|Proteobacteria,1RPU6@1236|Gammaproteobacteria,1XUDZ@135623|Vibrionales 135623|Vibrionales C Cbb3-type cytochrome oxidase, cytochrome c subunit ccoO - - ko:K00405 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002 3.D.4.3 - - FixO k141_24707_6 223926.28806533 5.92e-33 114.0 COG4736@1|root,COG4736@2|Bacteria,1NGAN@1224|Proteobacteria,1SGJ2@1236|Gammaproteobacteria,1XYUT@135623|Vibrionales 135623|Vibrionales O COG4736 Cbb3-type cytochrome oxidase, subunit 3 ccoQ - - ko:K00407 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002 3.D.4.3 - - FixQ k141_24707_7 223926.28806532 3.69e-231 636.0 COG2010@1|root,COG2010@2|Bacteria,1MUCW@1224|Proteobacteria,1RPYJ@1236|Gammaproteobacteria,1XSF6@135623|Vibrionales 135623|Vibrionales C C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex ccoP - - ko:K00406 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002 3.D.4.3 - - Cytochrome_CBB3,FixP_N k141_24707_8 1116375.VEJY3_07350 2.47e-99 289.0 COG3198@1|root,COG3198@2|Bacteria,1N75J@1224|Proteobacteria,1SC87@1236|Gammaproteobacteria,1XWXB@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria SO2360 - - ko:K09926 - - - - ko00000 - - - FixH k141_24707_9 1116375.VEJY3_07345 2.74e-98 306.0 COG2217@1|root,COG2608@1|root,COG2217@2|Bacteria,COG2608@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,1XSV0@135623|Vibrionales 135623|Vibrionales P cation transport ATPase ccoI - 3.6.3.4 ko:K01533 - - R00086 RC00002 ko00000,ko01000 3.A.3.5 - - ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase k141_22393_1 1294265.JCM21738_2557 2.38e-128 381.0 COG2972@1|root,COG2972@2|Bacteria,1UU89@1239|Firmicutes,4HECK@91061|Bacilli,1ZAUI@1386|Bacillus 91061|Bacilli T Histidine kinase - - 2.7.13.3 ko:K07718 ko02020,map02020 M00519 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,His_kinase k141_30508_2 1279017.AQYJ01000028_gene2126 9.27e-165 469.0 COG0583@1|root,COG0583@2|Bacteria,1QYAP@1224|Proteobacteria,1RYE8@1236|Gammaproteobacteria,46591@72275|Alteromonadaceae 1236|Gammaproteobacteria K Bacterial regulatory helix-turn-helix protein, lysR family - - - ko:K21699 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate k141_30508_3 1279017.AQYJ01000028_gene2127 6.73e-295 811.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,4641R@72275|Alteromonadaceae 1236|Gammaproteobacteria C belongs to the aldehyde dehydrogenase family gabD - 1.2.1.16,1.2.1.20,1.2.1.79 ko:K00135,ko:K15786 ko00250,ko00260,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00260,map00310,map00350,map00650,map00760,map01100,map01120 M00027 R00713,R00714,R02401,R09805 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_2158_1 1078085.HMPREF1210_02817 6.98e-11 60.5 COG1670@1|root,COG1670@2|Bacteria,1V1G0@1239|Firmicutes,4HG29@91061|Bacilli,26FA2@186818|Planococcaceae 91061|Bacilli J Acetyltransferase (GNAT) domain - - 2.3.1.82 ko:K00663 - - - - ko00000,ko01000,ko01504 - - - Acetyltransf_8 k141_28220_1 218284.CCDN010000005_gene3399 8.52e-164 462.0 COG0730@1|root,COG0730@2|Bacteria,1TPMA@1239|Firmicutes,4HCYJ@91061|Bacilli,1ZAPI@1386|Bacillus 91061|Bacilli S membrane transporter protein yunE - - ko:K07090 - - - - ko00000 - - - TauE k141_28220_2 218284.CCDN010000005_gene3398 7.46e-110 322.0 COG1801@1|root,COG1801@2|Bacteria,1TPX4@1239|Firmicutes,4HA0X@91061|Bacilli,1ZATP@1386|Bacillus 91061|Bacilli S Protein of unknown function DUF72 yunF - - - - - - - - - - - DUF72 k141_15208_1 1116375.VEJY3_07295 5.67e-153 432.0 COG1177@1|root,COG1177@2|Bacteria,1MVC5@1224|Proteobacteria,1RQB7@1236|Gammaproteobacteria,1XT48@135623|Vibrionales 135623|Vibrionales P Spermidine putrescine ABC transporter potC - - ko:K11070 ko02010,map02010 M00299 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 - - BPD_transp_1 k141_8009_1 223926.28809414 4.12e-219 612.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,1XSW9@135623|Vibrionales 135623|Vibrionales C Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid betB - 1.2.1.8 ko:K00130 ko00260,ko01100,map00260,map01100 M00555 R02565,R02566 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_8009_2 1219076.N646_4060 9.12e-131 372.0 COG1309@1|root,COG1309@2|Bacteria,1MX72@1224|Proteobacteria,1RZBH@1236|Gammaproteobacteria,1XTMB@135623|Vibrionales 135623|Vibrionales K Repressor involved in choline regulation of the bet genes betI - - ko:K02167 - - - - ko00000,ko03000 - - - TetR_C_6,TetR_N k141_8009_3 1116375.VEJY3_18581 1.03e-160 452.0 COG1028@1|root,COG1028@2|Bacteria,1MUBQ@1224|Proteobacteria,1RQJT@1236|Gammaproteobacteria,1XY81@135623|Vibrionales 135623|Vibrionales IQ KR domain - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 k141_8009_4 1116375.VEJY3_18576 6.41e-187 522.0 COG2084@1|root,COG2084@2|Bacteria,1RA7F@1224|Proteobacteria,1RMMY@1236|Gammaproteobacteria,1XVM6@135623|Vibrionales 135623|Vibrionales H Belongs to the 3-hydroxyisobutyrate dehydrogenase family - - 1.1.1.31 ko:K00020 ko00280,ko01100,map00280,map01100 - R05066 RC00099 ko00000,ko00001,ko01000 - - - NAD_binding_11,NAD_binding_2 k141_8009_5 1116375.VEJY3_18571 1.23e-145 419.0 COG1024@1|root,COG1024@2|Bacteria,1MU0B@1224|Proteobacteria,1RN07@1236|Gammaproteobacteria,1Y0NV@135623|Vibrionales 135623|Vibrionales I Enoyl-CoA hydratase/isomerase - - - - - - - - - - - - ECH_2 k141_4592_1 218284.CCDN010000003_gene2992 1.16e-211 595.0 COG1694@1|root,COG3956@2|Bacteria,1TPK1@1239|Firmicutes,4HA0A@91061|Bacilli,1ZAYB@1386|Bacillus 91061|Bacilli S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like yabN GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.66 ko:K02428,ko:K02499 ko00230,map00230 - R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000,ko03036 - - - MazG,TP_methylase k141_2159_1 1121939.L861_23570 1.74e-38 135.0 COG1309@1|root,COG1309@2|Bacteria,1RFK1@1224|Proteobacteria,1S5KJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator - - - - - - - - - - - - TetR_N k141_2159_2 1453501.JELR01000002_gene405 5.62e-30 119.0 COG0845@1|root,COG0845@2|Bacteria,1MUG6@1224|Proteobacteria,1RP16@1236|Gammaproteobacteria,4680U@72275|Alteromonadaceae 1236|Gammaproteobacteria M Secretion protein - - - ko:K01993 - - - - ko00000 - - - Biotin_lipoyl_2,HlyD_3 k141_21177_1 1042377.AFPJ01000030_gene434 3.23e-147 429.0 COG0389@1|root,COG0389@2|Bacteria,1MU5X@1224|Proteobacteria,1S28B@1236|Gammaproteobacteria,465IA@72275|Alteromonadaceae 1236|Gammaproteobacteria L Nucleotidyltransferase DNA polymerase involved in DNA repair imuB - - ko:K14161 - - - - ko00000,ko03400 - - - IMS k141_21177_2 1453501.JELR01000002_gene112 1.15e-114 335.0 COG4544@1|root,COG4544@2|Bacteria,1MZQU@1224|Proteobacteria,1S9RP@1236|Gammaproteobacteria,467W8@72275|Alteromonadaceae 1236|Gammaproteobacteria S Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division - - - ko:K13053,ko:K14160 - - - - ko00000,ko03036,ko03400 - - - RecA,SulA k141_15209_1 983917.RGE_10550 1.49e-17 87.8 COG1404@1|root,COG1404@2|Bacteria,1R6X8@1224|Proteobacteria 1224|Proteobacteria M Belongs to the peptidase S8 family - - - - - - - - - - - - Inhibitor_I9,PA,Peptidase_S8,fn3_5 k141_16508_2 1279017.AQYJ01000026_gene34 1.35e-30 108.0 2EK1G@1|root,33DRY@2|Bacteria,1NH6C@1224|Proteobacteria,1SGMZ@1236|Gammaproteobacteria,468WX@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF3012) - - - - - - - - - - - - DUF3012 k141_28221_1 218284.CCDN010000001_gene1243 1.8e-113 330.0 COG1028@1|root,COG1028@2|Bacteria,1TSQV@1239|Firmicutes,4HB3U@91061|Bacilli,1ZC75@1386|Bacillus 91061|Bacilli IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) ytkK - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 k141_17669_1 1230342.CTM_00730 1.01e-98 293.0 COG2323@1|root,COG2323@2|Bacteria,1V33F@1239|Firmicutes,24D59@186801|Clostridia,36H7E@31979|Clostridiaceae 186801|Clostridia S Protein of unknown function (DUF421) - - - - - - - - - - - - DUF421 k141_17669_2 218284.CCDN010000006_gene3516 3.51e-97 287.0 COG2364@1|root,COG2364@2|Bacteria,1V3NC@1239|Firmicutes,4HGRQ@91061|Bacilli,1ZCBH@1386|Bacillus 91061|Bacilli S Membrane - - - ko:K07149 - - - - ko00000 - - - YitT_membrane k141_3412_2 218284.CCDN010000001_gene1973 1.04e-82 250.0 COG0395@1|root,COG0395@2|Bacteria,1TR45@1239|Firmicutes,4HCEH@91061|Bacilli,1ZCMK@1386|Bacillus 91061|Bacilli G COG0395 ABC-type sugar transport system, permease component amyC1 - - ko:K10119 ko02010,map02010 M00196 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.28 - - BPD_transp_1 k141_31679_1 42565.FP66_12665 3.72e-52 176.0 COG0591@1|root,COG0591@2|Bacteria,1MUBI@1224|Proteobacteria,1SYH6@1236|Gammaproteobacteria,1XM6M@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - ko:K03307 - - - - ko00000 2.A.21 - - SSF k141_31679_2 42565.FP66_12660 2.62e-33 117.0 COG0251@1|root,COG0251@2|Bacteria,1RD2M@1224|Proteobacteria,1S3V7@1236|Gammaproteobacteria,1XJNU@135619|Oceanospirillales 135619|Oceanospirillales J Endoribonuclease L-PSP - - - - - - - - - - - - Ribonuc_L-PSP k141_8052_1 218284.CCDN010000001_gene609 4.72e-231 659.0 COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,4HB85@91061|Bacilli,1ZAS4@1386|Bacillus 91061|Bacilli J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner valS GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 k141_29688_1 218284.CCDN010000005_gene3298 1.43e-187 521.0 COG0061@1|root,COG0061@2|Bacteria,1TRB3@1239|Firmicutes,4HB08@91061|Bacilli,1ZAQP@1386|Bacillus 91061|Bacilli G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP nadK GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 - R00104 RC00002,RC00078 ko00000,ko00001,ko01000 - - iSB619.SA_RS04895 NAD_kinase k141_29688_2 265729.GS18_0200375 4.52e-17 80.1 COG0564@1|root,COG0564@2|Bacteria,1TS1T@1239|Firmicutes,4HBRY@91061|Bacilli,1ZB25@1386|Bacillus 91061|Bacilli J Responsible for synthesis of pseudouridine from uracil rluD GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23,5.4.99.28,5.4.99.29 ko:K06177,ko:K06180 - - - - ko00000,ko01000,ko03009,ko03016 - - - PseudoU_synth_2 k141_15239_1 754477.Q7C_1362 1.15e-114 337.0 COG0491@1|root,COG0491@2|Bacteria,1N0UK@1224|Proteobacteria,1S9V4@1236|Gammaproteobacteria,4634Y@72273|Thiotrichales 72273|Thiotrichales S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B k141_36525_2 1279017.AQYJ01000024_gene862 3.74e-05 44.3 COG0858@1|root,COG0858@2|Bacteria,1MZPE@1224|Proteobacteria,1S9AF@1236|Gammaproteobacteria,46857@72275|Alteromonadaceae 1236|Gammaproteobacteria J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA rbfA GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030490,GO:0033554,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043021,GO:0043024,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - ko:K02834 - - - - ko00000,ko03009 - - - RBFA k141_10635_2 436114.SYO3AOP1_0326 9.32e-27 114.0 COG0358@1|root,COG0358@2|Bacteria,2G3J2@200783|Aquificae 200783|Aquificae L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG - - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - Toprim_2,Toprim_4,Toprim_N,zf-CHC2 k141_29689_1 218284.CCDN010000005_gene3220 2.14e-99 311.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1TR2N@1239|Firmicutes,4H9RR@91061|Bacilli,1ZB2Q@1386|Bacillus 91061|Bacilli EU peptidase yuxL - 3.4.19.1 ko:K01303 - - - - ko00000,ko01000,ko01002 - - - PD40,Peptidase_S9 k141_3413_2 218284.CCDN010000005_gene3362 1.56e-86 258.0 2EA57@1|root,334A4@2|Bacteria,1VHEA@1239|Firmicutes,4HQU5@91061|Bacilli,1ZRA3@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_8053_1 398511.BpOF4_07725 4.24e-72 229.0 COG1167@1|root,COG1167@2|Bacteria,1TPS5@1239|Firmicutes,4H9M3@91061|Bacilli,1ZQA4@1386|Bacillus 91061|Bacilli EK COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs - - - ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 - R01939 RC00006 ko00000,ko00001,ko01000 - - - Aminotran_1_2,GntR k141_2194_1 1042377.AFPJ01000032_gene2754 1.84e-77 239.0 COG3226@1|root,COG3226@2|Bacteria,1PVE1@1224|Proteobacteria,1SGYI@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N k141_2194_2 1042377.AFPJ01000032_gene2756 2.01e-125 369.0 COG1680@1|root,COG1680@2|Bacteria,1MY01@1224|Proteobacteria,1RNUI@1236|Gammaproteobacteria 1236|Gammaproteobacteria V Beta-lactamase ampC GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008800,GO:0016787,GO:0016810,GO:0016812,GO:0042597,GO:0044464 3.5.2.6 ko:K01467,ko:K19100,ko:K19101,ko:K19215,ko:K20319,ko:K20320 ko01501,ko02020,map01501,map02020 M00628 R06363 RC01499 br01600,ko00000,ko00001,ko00002,ko01000,ko01504 - - - Beta-lactamase k141_34400_1 1121091.AUMP01000073_gene4042 2.56e-19 87.4 2BZV8@1|root,30HHG@2|Bacteria,1V68P@1239|Firmicutes,4HHRU@91061|Bacilli 91061|Bacilli S Replication-relaxation - - - - - - - - - - - - Replic_Relax k141_16546_2 1219076.N646_1170 3.2e-119 340.0 COG0521@1|root,COG0521@2|Bacteria,1R9W2@1224|Proteobacteria,1S21E@1236|Gammaproteobacteria,1XTIY@135623|Vibrionales 135623|Vibrionales H May be involved in the biosynthesis of molybdopterin moaB - 2.7.7.75 ko:K03638 ko00790,ko01100,map00790,map01100 - R09726 RC00002 ko00000,ko00001,ko01000 - - - MoCF_biosynth k141_16546_3 1280001.BAOA01000020_gene376 1.67e-102 297.0 COG0315@1|root,COG0315@2|Bacteria,1RCYZ@1224|Proteobacteria,1S3ST@1236|Gammaproteobacteria,1XURA@135623|Vibrionales 135623|Vibrionales H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) moaC GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.6.1.17 ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R11372 RC03425 ko00000,ko00001,ko01000 - - - MoaC k141_16546_4 674977.VMC_37380 8.96e-45 145.0 COG1977@1|root,COG1977@2|Bacteria,1N0IE@1224|Proteobacteria,1S8S1@1236|Gammaproteobacteria,1XYBT@135623|Vibrionales 135623|Vibrionales H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin moaD - - ko:K03636 ko04122,map04122 - - - ko00000,ko00001 - - - ThiS k141_16546_5 223926.28807085 2.72e-95 278.0 COG0314@1|root,COG0314@2|Bacteria,1RGUX@1224|Proteobacteria,1S5YH@1236|Gammaproteobacteria,1XX2Y@135623|Vibrionales 135623|Vibrionales H Molybdopterin converting factor, large subunit moaE GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016782,GO:0016783,GO:0018130,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0030366,GO:0032324,GO:0034641,GO:0042278,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.8.1.12 ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09395 RC02507 ko00000,ko00001,ko01000 - - - MoaE k141_16546_6 223926.28807084 2.25e-182 521.0 COG4166@1|root,COG4166@2|Bacteria,1P91R@1224|Proteobacteria,1RN57@1236|Gammaproteobacteria,1XTB9@135623|Vibrionales 135623|Vibrionales E COG4166 ABC-type oligopeptide transport system, periplasmic component oppA - - ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 k141_15240_1 42565.FP66_14970 3.48e-141 415.0 COG0326@1|root,COG0326@2|Bacteria,1MUUE@1224|Proteobacteria,1RNWD@1236|Gammaproteobacteria,1XHR3@135619|Oceanospirillales 135619|Oceanospirillales O Molecular chaperone. Has ATPase activity htpG - - ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 - - - ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 - - - HATPase_c,HATPase_c_3,HSP90 k141_31681_1 1453501.JELR01000002_gene1302 4.65e-135 385.0 COG3108@1|root,COG3108@2|Bacteria,1N3XU@1224|Proteobacteria,1SQF8@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Peptidase M15 - - - - - - - - - - - - Peptidase_M15_3 k141_29690_1 218284.CCDN010000001_gene1694 1.61e-87 273.0 COG2239@1|root,COG2239@2|Bacteria,1TP4V@1239|Firmicutes,4HASP@91061|Bacilli,1ZCSG@1386|Bacillus 91061|Bacilli P Acts as a magnesium transporter mgtE - - ko:K06213 - - - - ko00000,ko02000 1.A.26.1 - iYO844.BSU13300 CBS,MgtE,MgtE_N k141_2195_1 247639.MGP2080_00625 1.47e-85 262.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RM93@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed - - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N k141_33133_1 218284.CCDN010000006_gene3764 1.65e-85 274.0 COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,4HA3G@91061|Bacilli,1ZAVY@1386|Bacillus 91061|Bacilli T Diguanylate cyclase - - - - - - - - - - - - EAL,GAF_2,GGDEF,PAS,PAS_4,PAS_9 k141_28239_1 218284.CCDN010000002_gene2154 9.15e-121 347.0 COG0702@1|root,COG0702@2|Bacteria,1V112@1239|Firmicutes,4HEVN@91061|Bacilli,1ZG8I@1386|Bacillus 91061|Bacilli GM NAD(P)H-binding M1-688 - - - - - - - - - - - Epimerase,HIM1,NAD_binding_10 k141_28239_2 218284.CCDN010000002_gene2153 4.27e-46 155.0 2CABP@1|root,2Z7KZ@2|Bacteria,1U7V1@1239|Firmicutes,4HCY6@91061|Bacilli,1ZGH3@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_21201_1 223926.28807219 2.81e-08 55.8 COG0835@1|root,COG0835@2|Bacteria,1MYHY@1224|Proteobacteria,1S2TC@1236|Gammaproteobacteria,1XTG9@135623|Vibrionales 135623|Vibrionales NT Two component signalling adaptor domain VP2226 - - ko:K03408 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - CheW k141_21201_2 674977.VMC_12240 7.29e-171 478.0 COG1192@1|root,COG1192@2|Bacteria,1MWSE@1224|Proteobacteria,1RQ3X@1236|Gammaproteobacteria,1XUJC@135623|Vibrionales 135623|Vibrionales D COG1192 ATPases involved in chromosome partitioning - - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 k141_21201_3 1280001.BAOA01000009_gene4158 4.49e-228 632.0 COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,1RN67@1236|Gammaproteobacteria,1XU6C@135623|Vibrionales 135623|Vibrionales NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR cheB GO:0003674,GO:0003824,GO:0006935,GO:0008150,GO:0008984,GO:0009605,GO:0016787,GO:0016788,GO:0040011,GO:0042221,GO:0042330,GO:0050896,GO:0051723,GO:0052689,GO:0140096 3.1.1.61,3.5.1.44 ko:K03412 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 - - - CheB_methylest,Response_reg k141_21201_4 223926.28807222 0.0 1062.0 COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1XT18@135623|Vibrionales 135623|Vibrionales NT COG0643 Chemotaxis protein histidine kinase and related kinases cheA - 2.7.13.3 ko:K03407 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt k141_21201_5 1116375.VEJY3_11485 4.48e-152 430.0 COG3143@1|root,COG3143@2|Bacteria,1NIV6@1224|Proteobacteria,1RNG2@1236|Gammaproteobacteria,1XURP@135623|Vibrionales 135623|Vibrionales NT Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) cheZ - - ko:K03414 ko02030,map02030 - - - ko00000,ko00001,ko02035 - - - CheZ k141_21201_6 1219076.N646_1335 5.72e-85 250.0 COG0745@1|root,COG0745@2|Bacteria,1RDNP@1224|Proteobacteria,1S47I@1236|Gammaproteobacteria,1XWXK@135623|Vibrionales 135623|Vibrionales KT Transmits chemoreceptor signals to flagelllar motor components cheY - - ko:K03413 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - Response_reg k141_21201_7 223926.28807225 4.09e-163 457.0 COG1191@1|root,COG1191@2|Bacteria,1MWEU@1224|Proteobacteria,1RMKJ@1236|Gammaproteobacteria,1XSRM@135623|Vibrionales 135623|Vibrionales K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes fliA - - ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 - - - ko00000,ko00001,ko02035,ko03021 - - - Sigma70_r2,Sigma70_r3,Sigma70_r4 k141_21201_8 674977.VMC_12300 1.1e-197 549.0 COG0455@1|root,COG0455@2|Bacteria,1R8IW@1224|Proteobacteria,1RMZ2@1236|Gammaproteobacteria,1XTYQ@135623|Vibrionales 135623|Vibrionales D Belongs to the ParA family flhG - - ko:K04562 - - - - ko00000,ko02035 - - - ParA k141_21201_9 1116375.VEJY3_11505 1.66e-302 832.0 COG1419@1|root,COG1419@2|Bacteria,1MUQW@1224|Proteobacteria,1RMUU@1236|Gammaproteobacteria,1XTQT@135623|Vibrionales 135623|Vibrionales N Flagellar biosynthesis flhF - - ko:K02404 - - - - ko00000,ko02035 - - - SRP54 k141_21201_10 223926.28807228 0.0 1197.0 COG1298@1|root,COG1298@2|Bacteria,1MUF3@1224|Proteobacteria,1RMSM@1236|Gammaproteobacteria,1XSJN@135623|Vibrionales 135623|Vibrionales N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin flhA - - ko:K02400 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 - - FHIPEP k141_3414_1 1382359.JIAL01000001_gene2624 4.14e-85 263.0 COG1131@1|root,COG1131@2|Bacteria,3Y3I9@57723|Acidobacteria,2JIPJ@204432|Acidobacteriia 204432|Acidobacteriia V AAA domain, putative AbiEii toxin, Type IV TA system - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_34401_1 218284.CCDN010000004_gene3128 2.66e-207 579.0 COG0477@1|root,COG2814@2|Bacteria,1U72T@1239|Firmicutes,4HCHH@91061|Bacilli,1ZCHP@1386|Bacillus 91061|Bacilli EGP COG0477 Permeases of the major facilitator superfamily ykuC - - - - - - - - - - - MFS_1 k141_36526_1 404589.Anae109_4478 3.07e-52 191.0 COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,42N8X@68525|delta/epsilon subdivisions,2WIVR@28221|Deltaproteobacteria,2YUID@29|Myxococcales 28221|Deltaproteobacteria L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd - - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF k141_28240_1 1453501.JELR01000001_gene2373 1.47e-92 297.0 COG1629@1|root,COG4771@2|Bacteria,1N6JG@1224|Proteobacteria,1RP10@1236|Gammaproteobacteria,465FE@72275|Alteromonadaceae 1236|Gammaproteobacteria P Carboxypeptidase regulatory-like domain - - - - - - - - - - - - CarboxypepD_reg,Plug,TonB_dep_Rec k141_31683_1 935837.JAEK01000063_gene3984 9.91e-51 166.0 COG0454@1|root,COG0454@2|Bacteria,1UJ4V@1239|Firmicutes,4IT1F@91061|Bacilli,1ZHBU@1386|Bacillus 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10 k141_16547_1 1453501.JELR01000005_gene1581 9.55e-255 723.0 COG2273@1|root,COG3488@1|root,COG2273@2|Bacteria,COG3488@2|Bacteria,1MXUW@1224|Proteobacteria,1RRXK@1236|Gammaproteobacteria,464KW@72275|Alteromonadaceae 1236|Gammaproteobacteria C Di-haem oxidoreductase, putative peroxidase - - - - - - - - - - - - CBM_6,DHOR,F5_F8_type_C,Glyco_hydro_16,Lipoprotein_15,TSP_3 k141_33134_1 1042377.AFPJ01000043_gene851 1.91e-76 238.0 COG3214@1|root,COG3214@2|Bacteria,1N40B@1224|Proteobacteria,1RPYB@1236|Gammaproteobacteria,469ZV@72275|Alteromonadaceae 1236|Gammaproteobacteria S Winged helix DNA-binding domain ycaQ - - ko:K09927 - - - - ko00000 - - - HTH_42 k141_33134_2 1453501.JELR01000002_gene1414 0.000446 43.1 COG1878@1|root,COG1878@2|Bacteria,1MWWB@1224|Proteobacteria,1RS83@1236|Gammaproteobacteria,46DJ7@72275|Alteromonadaceae 1236|Gammaproteobacteria S Putative cyclase - - - - - - - - - - - - Cyclase k141_37826_1 1323663.AROI01000024_gene1549 1.85e-78 242.0 COG0600@1|root,COG0600@2|Bacteria,1MVAE@1224|Proteobacteria,1RPEN@1236|Gammaproteobacteria 1236|Gammaproteobacteria P ABC-type nitrate sulfonate bicarbonate transport system permease component - - - ko:K02050 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - BPD_transp_1 k141_37826_2 1323663.AROI01000024_gene1550 3.67e-123 359.0 COG1116@1|root,COG1116@2|Bacteria,1MUIM@1224|Proteobacteria,1RRG7@1236|Gammaproteobacteria 1236|Gammaproteobacteria P ABC-type nitrate sulfonate bicarbonate transport system, ATPase component - - - ko:K02049 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - ABC_tran k141_3415_1 1347086.CCBA010000005_gene4074 2.62e-66 226.0 COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,4HAFP@91061|Bacilli,1ZBJ3@1386|Bacillus 91061|Bacilli V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran k141_8056_1 323098.Nwi_0254 1.96e-52 185.0 COG1475@1|root,COG2801@1|root,COG2963@1|root,COG1475@2|Bacteria,COG2801@2|Bacteria,COG2963@2|Bacteria,1PBHA@1224|Proteobacteria,2TRQF@28211|Alphaproteobacteria,3JS1E@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L leucine-zipper of insertion element IS481 - - 2.7.7.49 ko:K00986,ko:K07497 - - - - ko00000,ko01000 - - - HTH_32,rve k141_28241_1 218284.CCDN010000001_gene624 4.7e-48 159.0 COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,4HB1W@91061|Bacilli,1ZBYH@1386|Bacillus 91061|Bacilli E Belongs to the UPF0758 family radC - - ko:K03630 - - - - ko00000 - - - RadC k141_28241_2 1196324.A374_11390 1.69e-42 145.0 COG0424@1|root,COG0424@2|Bacteria,1V6FH@1239|Firmicutes,4HIMK@91061|Bacilli 91061|Bacilli D septum formation protein Maf maf GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0005575,GO:0005623,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0022402,GO:0022607,GO:0030428,GO:0032506,GO:0044085,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0090529,GO:1902410,GO:1903047 - ko:K06287 - - - - ko00000 - - - Maf k141_10637_1 1348657.M622_05555 3.94e-51 174.0 COG0695@1|root,COG0695@2|Bacteria,1QVSK@1224|Proteobacteria,2VH4R@28216|Betaproteobacteria,2KWA6@206389|Rhodocyclales 206389|Rhodocyclales O Glutaredoxin - - - - - - - - - - - - Glutaredoxin k141_10637_2 1116472.MGMO_171c00110 1.01e-51 178.0 COG0224@1|root,COG0224@2|Bacteria,1RIE5@1224|Proteobacteria,1S3ZW@1236|Gammaproteobacteria,1XF9U@135618|Methylococcales 135618|Methylococcales C ATP synthase - - - ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt k141_10637_3 1131553.JIBI01000039_gene1942 1.56e-31 123.0 COG0056@1|root,COG0056@2|Bacteria,1MVHM@1224|Proteobacteria,2VPGJ@28216|Betaproteobacteria,3728R@32003|Nitrosomonadales 28216|Betaproteobacteria F Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit atpA2 - 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N k141_29694_1 1294265.JCM21738_4638 7.63e-30 112.0 COG4768@1|root,COG4768@2|Bacteria,1VAXN@1239|Firmicutes,4HM93@91061|Bacilli,1ZGYS@1386|Bacillus 91061|Bacilli S protein containing a divergent version of the methyl-accepting chemotaxis-like domain ytxG - - - - - - - - - - - DUF948 k141_36527_1 1279017.AQYJ01000024_gene836 1.63e-210 597.0 COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,1RME8@1236|Gammaproteobacteria,464T9@72275|Alteromonadaceae 1236|Gammaproteobacteria O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins ftsH GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - ko:K03798 - M00742 - - ko00000,ko00002,ko01000,ko01002,ko03110 - - - AAA,FtsH_ext,Peptidase_M41 k141_17710_2 1408439.JHXW01000001_gene1872 1.35e-54 187.0 COG3183@1|root,COG3183@2|Bacteria 2|Bacteria L HNH endonuclease - - - ko:K07451 - - - - ko00000,ko01000,ko02048 - - - DUF3578,DUF3883,HNH k141_17710_3 675816.VIA_000755 1.45e-258 717.0 28IFE@1|root,2Z8H5@2|Bacteria,1PNBC@1224|Proteobacteria,1S5GF@1236|Gammaproteobacteria,1XXYW@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_17710_4 675816.VIA_000754 0.0 2088.0 COG0210@1|root,COG0515@1|root,COG1112@1|root,COG0210@2|Bacteria,COG0515@2|Bacteria,COG1112@2|Bacteria,1MWW9@1224|Proteobacteria,1RP8R@1236|Gammaproteobacteria,1XVTF@135623|Vibrionales 135623|Vibrionales L AAA domain - - - - - - - - - - - - AAA_11,AAA_12,NERD k141_4609_2 223926.28808023 0.0 1172.0 COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,1RNH8@1236|Gammaproteobacteria,1XUXR@135623|Vibrionales 135623|Vibrionales H Belongs to the UbiD family ubiD GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008694,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.1.1.98 ko:K03182 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04985,R04986 RC00391 ko00000,ko00001,ko00002,ko01000 - - - UbiD k141_4609_3 1116375.VEJY3_15115 1.73e-196 549.0 2FIIZ@1|root,34AB0@2|Bacteria,1P1Z4@1224|Proteobacteria,1SSJF@1236|Gammaproteobacteria,1XU8I@135623|Vibrionales 135623|Vibrionales - - VV10936 - - - - - - - - - - - - k141_4609_4 1280001.BAOA01000024_gene5220 2.83e-299 816.0 COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,1RP95@1236|Gammaproteobacteria,1XT0A@135623|Vibrionales 135623|Vibrionales K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template rho - - ko:K03628 ko03018,map03018 - - - ko00000,ko00001,ko03019,ko03021 - - - ATP-synt_ab,Rho_N,Rho_RNA_bind k141_8455_1 1279015.KB908456_gene1525 1.03e-38 141.0 COG0295@1|root,COG0295@2|Bacteria,1MY2R@1224|Proteobacteria,1RMRX@1236|Gammaproteobacteria,1Y5M3@135624|Aeromonadales 135624|Aeromonadales F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis cdd - 3.5.4.5 ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R01878,R02485,R08221 RC00074,RC00514 ko00000,ko00001,ko01000 - - - dCMP_cyt_deam_1,dCMP_cyt_deam_2 k141_27404_1 1218352.B597_021480 1.12e-05 48.1 COG2267@1|root,COG2267@2|Bacteria,1MX0N@1224|Proteobacteria,1SBW4@1236|Gammaproteobacteria,1Z1G4@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria I hydrolases or acyltransferases (alpha beta hydrolase superfamily) pcaD - 3.1.1.24 ko:K01055 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00568 R02991 RC00825 ko00000,ko00001,ko00002,ko01000 - - - Abhydrolase_1,Abhydrolase_4 k141_27404_2 1042377.AFPJ01000016_gene114 1.76e-35 126.0 COG2353@1|root,COG2353@2|Bacteria,1MZDI@1224|Proteobacteria,1S9EZ@1236|Gammaproteobacteria,467TE@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the UPF0312 family - - - - - - - - - - - - YceI k141_13208_1 1117379.BABA_05711 2.48e-35 122.0 2EICG@1|root,33C3S@2|Bacteria,1VP3K@1239|Firmicutes,4HRR3@91061|Bacilli,1ZHXW@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_13208_2 1196029.ALIM01000034_gene1614 1.37e-68 209.0 2EA9N@1|root,334E2@2|Bacteria,1VEP2@1239|Firmicutes,4HJ3E@91061|Bacilli,1ZG6V@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_13208_3 1384057.CD33_07375 4.76e-76 228.0 COG3877@1|root,COG3877@2|Bacteria,1VAFG@1239|Firmicutes,4HJ4J@91061|Bacilli,3IY09@400634|Lysinibacillus 91061|Bacilli S Protein of unknown function (DUF2089) - - - - - - - - - - - - DUF2089 k141_23845_1 1121121.KB894294_gene4794 2.7e-07 50.8 COG0454@1|root,COG0456@2|Bacteria,1V2FB@1239|Firmicutes,4HFUN@91061|Bacilli,26V2J@186822|Paenibacillaceae 91061|Bacilli K GNAT family acetyltransferase yhfO - - - - - - - - - - - Acetyltransf_1,Acetyltransf_4 k141_23845_2 1122927.KB895416_gene3311 8.16e-54 177.0 COG1011@1|root,COG1011@2|Bacteria,1V7DX@1239|Firmicutes,4HK44@91061|Bacilli,26TNE@186822|Paenibacillaceae 91061|Bacilli S Hydrolase - - - ko:K07025 - - - - ko00000 - - - HAD_2 k141_20273_1 1116375.VEJY3_03225 2.67e-138 412.0 COG0457@1|root,COG0457@2|Bacteria,1RDRI@1224|Proteobacteria,1S3PB@1236|Gammaproteobacteria,1XTIH@135623|Vibrionales 135623|Vibrionales S COG0457 FOG TPR repeat - - - - - - - - - - - - TPR_12 k141_14378_2 218284.CCDN010000001_gene1440 3.61e-23 89.7 2A051@1|root,30N7S@2|Bacteria,1UAQ6@1239|Firmicutes,4IM2V@91061|Bacilli,1ZIY8@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_14378_3 1340434.AXVA01000003_gene1569 6.88e-101 306.0 COG4585@1|root,COG4585@2|Bacteria,1TSUE@1239|Firmicutes,4HB9N@91061|Bacilli,1ZBZR@1386|Bacillus 91061|Bacilli T Histidine kinase desK GO:0003674,GO:0003824,GO:0004721,GO:0005488,GO:0005515,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0036211,GO:0042578,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 2.7.13.3 ko:K07778 ko02020,map02020 M00479 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA_3 k141_7212_1 218284.CCDN010000001_gene1062 4.21e-136 394.0 COG0755@1|root,COG0755@2|Bacteria,1TQZ4@1239|Firmicutes,4HA2N@91061|Bacilli,1ZBH9@1386|Bacillus 91061|Bacilli O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component' resC GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008152,GO:0015886,GO:0016020,GO:0044464,GO:0051179,GO:0051181,GO:0051234,GO:0055114,GO:0071702,GO:0071705,GO:0071944,GO:1901678 - - - - - - - - - - Cytochrom_C_asm k141_29802_1 218284.CCDN010000001_gene603 2.69e-63 201.0 COG1587@1|root,COG1587@2|Bacteria,1UHSJ@1239|Firmicutes,4HFY4@91061|Bacilli,1ZGER@1386|Bacillus 91061|Bacilli H Uroporphyrinogen-III synthase hemD - 4.2.1.75 ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R03165 RC01861 ko00000,ko00001,ko00002,ko01000 - - - HEM4 k141_29802_2 218284.CCDN010000001_gene604 3.18e-205 570.0 COG0113@1|root,COG0113@2|Bacteria,1TP09@1239|Firmicutes,4HBQC@91061|Bacilli,1ZARK@1386|Bacillus 91061|Bacilli H Belongs to the ALAD family hemB GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00036 RC00918,RC01781 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ALAD k141_13209_1 586416.GZ22_08435 6.73e-101 306.0 COG0699@1|root,COG0699@2|Bacteria,1TPPG@1239|Firmicutes,4HBH1@91061|Bacilli 91061|Bacilli S ATPase. Has a role at an early stage in the morphogenesis of the spore coat spoIVA GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009653,GO:0009847,GO:0009987,GO:0010927,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022607,GO:0030154,GO:0030203,GO:0030312,GO:0030435,GO:0030554,GO:0031160,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0032989,GO:0034622,GO:0035639,GO:0036094,GO:0042244,GO:0042546,GO:0042601,GO:0042763,GO:0043167,GO:0043168,GO:0043170,GO:0043591,GO:0043595,GO:0043933,GO:0043934,GO:0044085,GO:0044426,GO:0044462,GO:0044464,GO:0045229,GO:0048646,GO:0048856,GO:0048869,GO:0051258,GO:0051259,GO:0065003,GO:0070499,GO:0070590,GO:0070726,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 - ko:K06398 - - - - ko00000 - - - Spore_IV_A k141_28656_1 1279017.AQYJ01000028_gene2401 5.72e-126 393.0 COG1523@1|root,COG1523@2|Bacteria,1MU19@1224|Proteobacteria,1RP6F@1236|Gammaproteobacteria,465SK@72275|Alteromonadaceae 1236|Gammaproteobacteria G Belongs to the glycosyl hydrolase 13 family pulA - 3.2.1.41 ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 - R02111 - ko00000,ko00001,ko01000 - CBM48,GH13 - Alpha-amylase,CBM_48,DUF3372,PUD k141_126_1 218284.CCDN010000002_gene2871 5.67e-95 281.0 COG4565@1|root,COG4565@2|Bacteria,1V1D7@1239|Firmicutes,4HFWB@91061|Bacilli,1ZFEC@1386|Bacillus 91061|Bacilli T response regulator citT - - ko:K11638 ko02020,map02020 M00487 - - ko00000,ko00001,ko00002,ko02022 - - - CitT,HTH_11,Response_reg k141_34580_1 218284.CCDN010000006_gene3599 2.14e-147 438.0 COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,4HAI0@91061|Bacilli,1ZAVE@1386|Bacillus 91061|Bacilli P P-type ATPase copA - 3.6.3.54 ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - - E1-E2_ATPase,HMA,Hydrolase k141_34580_2 218284.CCDN010000006_gene3598 2.14e-43 142.0 2DNDI@1|root,32WZ0@2|Bacteria,1VG75@1239|Firmicutes,4HQ78@91061|Bacilli 91061|Bacilli S Glutaredoxin - - - - - - - - - - - - Glutaredoxin k141_19106_1 69395.JQLZ01000006_gene2008 3.75e-11 65.1 COG4772@1|root,COG4772@2|Bacteria,1QVGF@1224|Proteobacteria,2TWFE@28211|Alphaproteobacteria,2KFMN@204458|Caulobacterales 204458|Caulobacterales P TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_19106_2 1177181.T9A_00348 2.15e-10 58.9 COG0517@1|root,COG0517@2|Bacteria,1QTZR@1224|Proteobacteria,1S7SY@1236|Gammaproteobacteria,1XKDN@135619|Oceanospirillales 135619|Oceanospirillales S COG0517 FOG CBS domain - - - - - - - - - - - - BON,CBS k141_22694_1 1267534.KB906760_gene1581 6.76e-33 134.0 COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria 2|Bacteria S cAMP biosynthetic process - - - - - - - - - - - - TPR_16,TPR_8 k141_36913_1 218284.CCDN010000005_gene3189 1.74e-131 375.0 COG2197@1|root,COG2197@2|Bacteria,1TQ1U@1239|Firmicutes,4HE6R@91061|Bacilli,1ZD6A@1386|Bacillus 91061|Bacilli T Bacterial regulatory proteins, luxR family - - - ko:K11618 ko02020,map02020 M00481,M00754 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg k141_17990_1 218284.CCDN010000002_gene2798 1.16e-46 171.0 COG0308@1|root,COG0577@1|root,COG4591@1|root,COG0308@2|Bacteria,COG0577@2|Bacteria,COG4591@2|Bacteria,1TSZH@1239|Firmicutes,4HCKC@91061|Bacilli 91061|Bacilli MV FtsX-like permease family - - - - - - - - - - - - FtsX k141_22724_1 309801.trd_A0394 6.2e-77 248.0 COG0843@1|root,COG0843@2|Bacteria,2G628@200795|Chloroflexi,27YW1@189775|Thermomicrobia 189775|Thermomicrobia C Cytochrome C and Quinol oxidase polypeptide I - - 1.9.3.1 ko:K02274 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6 - - COX1 k141_29822_1 1042377.AFPJ01000037_gene2947 8.51e-122 350.0 COG0259@1|root,COG0259@2|Bacteria,1NZUU@1224|Proteobacteria,1RMQ2@1236|Gammaproteobacteria,466CT@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) pdxH GO:0000166,GO:0003674,GO:0003824,GO:0004733,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009108,GO:0009110,GO:0009443,GO:0009987,GO:0010181,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019842,GO:0032553,GO:0032991,GO:0034641,GO:0036094,GO:0042301,GO:0042364,GO:0042802,GO:0042803,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0043094,GO:0043167,GO:0043168,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902444 1.4.3.5 ko:K00275 ko00750,ko01100,ko01120,map00750,map01100,map01120 M00124 R00277,R00278,R01710,R01711 RC00048,RC00116 ko00000,ko00001,ko00002,ko01000 - - - PNP_phzG_C,Putative_PNPOx k141_25056_1 1307436.PBF_00420 6.8e-82 246.0 COG0454@1|root,COG0456@2|Bacteria,1V6D6@1239|Firmicutes,4HIQX@91061|Bacilli,1ZGF7@1386|Bacillus 91061|Bacilli K Acetyltransferase (GNAT) domain yxbD GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0044424,GO:0044464 3.2.2.20 ko:K01246 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Acetyltransf_1 k141_25056_2 218284.CCDN010000001_gene427 0.000134 43.9 2C0SV@1|root,33X5Q@2|Bacteria,1VW58@1239|Firmicutes,4HWC1@91061|Bacilli 91061|Bacilli S Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10 k141_32184_1 1453501.JELR01000001_gene3027 8.69e-17 75.5 COG1959@1|root,COG1959@2|Bacteria,1RDA4@1224|Proteobacteria,1S3RW@1236|Gammaproteobacteria,466UA@72275|Alteromonadaceae 1236|Gammaproteobacteria K Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins iscR GO:0003674,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 - ko:K13643 - - - - ko00000,ko03000 - - - Rrf2 k141_28683_1 218284.CCDN010000007_gene3983 2.73e-55 182.0 COG0009@1|root,COG0009@2|Bacteria,1TP1I@1239|Firmicutes,4HA7W@91061|Bacilli,1ZB2V@1386|Bacillus 91061|Bacilli J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine ywlC GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87 ko:K07566 - - R10463 RC00745 ko00000,ko01000,ko03009,ko03016 - - - SUA5,Sua5_yciO_yrdC k141_28683_2 218284.CCDN010000007_gene3982 4.89e-82 244.0 COG1246@1|root,COG1246@2|Bacteria,1U9KN@1239|Firmicutes,4IN7D@91061|Bacilli,1ZJ7M@1386|Bacillus 91061|Bacilli E Belongs to the acetyltransferase family. ArgA subfamily - - - - - - - - - - - - Acetyltransf_1 k141_11993_1 411468.CLOSCI_00575 5.99e-74 234.0 COG0270@1|root,COG0270@2|Bacteria,1V3W2@1239|Firmicutes,24HK1@186801|Clostridia,22348@1506553|Lachnoclostridium 186801|Clostridia L C-5 cytosine-specific DNA methylase - - 2.1.1.37 ko:K17398 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko03032,ko03036 - - - DNA_methylase k141_163_1 218284.CCDN010000002_gene2070 3.58e-126 380.0 COG1199@1|root,COG1199@2|Bacteria,1TPNB@1239|Firmicutes,4HD6T@91061|Bacilli,1ZAUN@1386|Bacillus 91061|Bacilli KL DEAD_2 uvrB3 - 3.1.12.1 ko:K07464 - - - - ko00000,ko01000,ko02048 - - - DEAD,DEAD_2,HBB,Helicase_C_2,PDDEXK_1 k141_29824_1 1294265.JCM21738_5324 1.04e-102 310.0 COG2374@1|root,COG4085@1|root,COG2374@2|Bacteria,COG4085@2|Bacteria,1VKCH@1239|Firmicutes,4IS9P@91061|Bacilli,1ZS3V@1386|Bacillus 91061|Bacilli S Endonuclease/Exonuclease/phosphatase family - - - ko:K07004 - - - - ko00000 - - - CHB_HEX_C_1,Exo_endo_phos k141_17992_1 314292.VAS14_21131 9.07e-109 337.0 COG1629@1|root,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria,1XV5Z@135623|Vibrionales 135623|Vibrionales HP TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_3708_1 1279017.AQYJ01000028_gene2333 2.07e-94 290.0 COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,1RN3V@1236|Gammaproteobacteria,463ZU@72275|Alteromonadaceae 1236|Gammaproteobacteria FP Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the stringent response , an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities gppA - 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 - R03409 RC00002 ko00000,ko00001,ko01000 - - - HD,Ppx-GppA k141_20297_1 218284.CCDN010000005_gene3400 3.38e-125 367.0 COG0737@1|root,COG0737@2|Bacteria,1TQCW@1239|Firmicutes,4HAUC@91061|Bacilli,1ZCJ8@1386|Bacillus 91061|Bacilli F Belongs to the 5'-nucleotidase family yunD - 3.1.3.5 ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - 5_nucleotid_C,Metallophos k141_27428_1 1121028.ARQE01000016_gene2619 6.94e-51 169.0 COG2801@1|root,COG2801@2|Bacteria,1MVN5@1224|Proteobacteria,2TQK0@28211|Alphaproteobacteria,2PK0U@255475|Aurantimonadaceae 28211|Alphaproteobacteria L Integrase core domain - - - - - - - - - - - - HTH_21,rve,rve_3 k141_27428_2 351016.RAZWK3B_17388 7.29e-45 146.0 COG2963@1|root,COG2963@2|Bacteria,1RGZ5@1224|Proteobacteria,2UAIS@28211|Alphaproteobacteria,2P3SI@2433|Roseobacter 28211|Alphaproteobacteria L COG2801 Transposase and inactivated derivatives - - - - - - - - - - - - HTH_Tnp_1 k141_7238_2 768706.Desor_1457 6.25e-42 145.0 COG1131@1|root,COG1131@2|Bacteria,1TQHS@1239|Firmicutes,24941@186801|Clostridia,2613U@186807|Peptococcaceae 186801|Clostridia V ABC transporter - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_16738_1 218284.CCDN010000001_gene1004 8.74e-183 517.0 COG0362@1|root,COG0362@2|Bacteria,1TP4I@1239|Firmicutes,4H9NC@91061|Bacilli,1ZC6M@1386|Bacillus 91061|Bacilli G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH gnd - 1.1.1.343,1.1.1.44 ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 M00004,M00006 R01528,R10221 RC00001,RC00539 ko00000,ko00001,ko00002,ko01000 - - - 6PGD,NAD_binding_2 k141_22725_1 240302.BN982_01095 2.44e-61 193.0 COG1435@1|root,COG1435@2|Bacteria,1TRVM@1239|Firmicutes,4HA4A@91061|Bacilli,3NDIP@45667|Halobacillus 91061|Bacilli F Thymidine kinase tdk GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R01567,R02099,R08233 RC00002,RC00017 ko00000,ko00001,ko01000 - - iYO844.BSU37060 TK k141_36939_1 1397528.Q671_04565 4.19e-81 265.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - EAL,GAF,GAF_2,GGDEF,HAMP,PAS_3,PAS_4,PAS_8 k141_2515_1 218284.CCDN010000001_gene1194 1.82e-38 135.0 COG2265@1|root,COG2265@2|Bacteria,1V4AQ@1239|Firmicutes,4HHBA@91061|Bacilli,1ZCTE@1386|Bacillus 91061|Bacilli J Putative SAM-dependent methyltransferase - - - - - - - - - - - - SAM_MT k141_29825_1 1172179.AUKV01000003_gene7328 5.61e-34 127.0 COG0451@1|root,COG0451@2|Bacteria,2I2SW@201174|Actinobacteria 201174|Actinobacteria GM PFAM NAD-dependent epimerase dehydratase - - - - - - - - - - - - Epimerase k141_14406_1 1177154.Y5S_01706 3.83e-78 266.0 COG1361@1|root,COG1361@2|Bacteria,1QVSF@1224|Proteobacteria 1224|Proteobacteria M domain protein - - - - - - - - - - - - CARDB,DUF11,OmpA_membrane k141_11995_1 1279017.AQYJ01000027_gene1667 3.65e-87 270.0 COG2223@1|root,COG2223@2|Bacteria,1MU27@1224|Proteobacteria,1RMUK@1236|Gammaproteobacteria,4652C@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG2223 Nitrate nitrite transporter narK1 - - ko:K02575 ko00910,map00910 M00615 - - ko00000,ko00001,ko00002,ko02000 2.A.1.8 - - MFS_1 k141_16739_1 218284.CCDN010000001_gene1819 1.8e-28 110.0 COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,4HAD5@91061|Bacilli,1ZC3C@1386|Bacillus 91061|Bacilli E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases gltD - 1.3.1.1 ko:K17722 ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100 M00046 R00977,R01414,R11026 RC00072,RC00123 ko00000,ko00001,ko00002,ko01000 - - - Fer4_20,Pyr_redox_2,Pyr_redox_3 k141_16739_2 714961.BFZC1_21508 6.63e-94 284.0 COG0167@1|root,COG1146@1|root,COG0167@2|Bacteria,COG1146@2|Bacteria,1TRPI@1239|Firmicutes,4HBRG@91061|Bacilli,3IXDB@400634|Lysinibacillus 91061|Bacilli C catalyzes the conversion of pyrimidines to 5,6-dihydro compounds in pyrimidine degradation - - 1.3.1.1 ko:K17723 ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100 M00046 R00977,R01414,R11026 RC00072,RC00123 ko00000,ko00001,ko00002,ko01000 - - - DHO_dh,Fer4_21 k141_31055_2 566466.NOR53_43 5.63e-63 193.0 COG0051@1|root,COG0051@2|Bacteria,1RGWF@1224|Proteobacteria,1S3QX@1236|Gammaproteobacteria,1J66Z@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Involved in the binding of tRNA to the ribosomes rpsJ GO:0001072,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0015935,GO:0019219,GO:0019222,GO:0019538,GO:0022626,GO:0022627,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043244,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0140110,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2001141 - ko:K02946 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S10 k141_13239_1 218284.CCDN010000007_gene3820 4.64e-76 229.0 2BEBR@1|root,3282S@2|Bacteria,1V6PA@1239|Firmicutes,4HM09@91061|Bacilli,1ZQIB@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_13239_2 218284.CCDN010000007_gene3821 6.76e-28 103.0 2E6P8@1|root,3319M@2|Bacteria,1VIXA@1239|Firmicutes,4HP8N@91061|Bacilli,1ZJ65@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_164_2 1042377.AFPJ01000026_gene2594 7.29e-68 207.0 COG2142@1|root,COG2142@2|Bacteria,1MZR9@1224|Proteobacteria,1S9TS@1236|Gammaproteobacteria,467WQ@72275|Alteromonadaceae 1236|Gammaproteobacteria C Membrane-anchoring subunit of succinate dehydrogenase (SDH) sdhD GO:0000104,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0016999,GO:0017004,GO:0017144,GO:0019752,GO:0020037,GO:0022607,GO:0022900,GO:0032991,GO:0034622,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0065003,GO:0070469,GO:0070470,GO:0071704,GO:0071840,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901363,GO:1902494,GO:1990204 - ko:K00242 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173 R02164 RC00045 ko00000,ko00001,ko00002 - - e_coli_core.b0722,iAF1260.b0722,iAPECO1_1312.APECO1_1356,iB21_1397.B21_00671,iBWG_1329.BWG_0581,iE2348C_1286.E2348C_0602,iEC042_1314.EC042_0740,iECABU_c1320.ECABU_c07680,iECBD_1354.ECBD_2938,iECB_1328.ECB_00682,iECDH10B_1368.ECDH10B_0789,iECDH1ME8569_1439.ECDH1ME8569_0681,iECD_1391.ECD_00682,iECED1_1282.ECED1_0692,iECIAI1_1343.ECIAI1_0696,iECIAI39_1322.ECIAI39_0680,iECNA114_1301.ECNA114_0658,iECO103_1326.ECO103_0716,iECO111_1330.ECO111_0739,iECO26_1355.ECO26_0783,iECOK1_1307.ECOK1_0722,iECP_1309.ECP_0734,iECS88_1305.ECS88_0748,iECSE_1348.ECSE_0782,iECSF_1327.ECSF_0655,iECUMN_1333.ECUMN_0800,iECW_1372.ECW_m0777,iEKO11_1354.EKO11_3157,iETEC_1333.ETEC_0733,iEcDH1_1363.EcDH1_2913,iEcE24377_1341.EcE24377A_0749,iEcHS_1320.EcHS_A0770,iEcSMS35_1347.EcSMS35_0735,iEcolC_1368.EcolC_2933,iJO1366.b0722,iJR904.b0722,iLF82_1304.LF82_2100,iNRG857_1313.NRG857_03215,iSBO_1134.SBO_0580,iSDY_1059.SDY_0660,iSFV_1184.SFV_0613,iSF_1195.SF0575,iSFxv_1172.SFxv_0634,iSSON_1240.SSON_0673,iS_1188.S0588,iUMN146_1321.UM146_14010,iUMNK88_1353.UMNK88_758,iUTI89_1310.UTI89_C0718,iWFL_1372.ECW_m0777,iY75_1357.Y75_RS03755,ic_1306.c0800 Sdh_cyt k141_164_3 1415778.JQMM01000001_gene1809 7.07e-40 136.0 COG2009@1|root,COG2009@2|Bacteria,1RIGZ@1224|Proteobacteria,1S5ZE@1236|Gammaproteobacteria,1J6QM@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C COG2009 Succinate dehydrogenase fumarate reductase, cytochrome b subunit sdhC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002 - - - Sdh_cyt k141_26300_1 1116375.VEJY3_01865 2.4e-260 716.0 COG0617@1|root,COG0617@2|Bacteria,1MU2X@1224|Proteobacteria,1RPFJ@1236|Gammaproteobacteria,1XT9B@135623|Vibrionales 135623|Vibrionales F Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases cca GO:0003674,GO:0003824,GO:0004652,GO:0004810,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0070566,GO:0071704,GO:0090304,GO:1901360,GO:1990817 2.7.7.72 ko:K00974 ko03013,map03013 - R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016 - - - HD,PolyA_pol,PolyA_pol_RNAbd k141_26300_2 1116375.VEJY3_01870 9.39e-309 851.0 COG3267@1|root,COG3409@1|root,COG3267@2|Bacteria,COG3409@2|Bacteria,1MU3G@1224|Proteobacteria,1RMI0@1236|Gammaproteobacteria,1XSH3@135623|Vibrionales 135623|Vibrionales MU general secretion pathway protein exeA - - ko:K02450 - M00331 - - ko00000,ko00002,ko02044 9.B.42 - - AAA_22,PG_binding_1,T2SSB k141_26300_3 223926.28805399 6.72e-79 243.0 COG3267@1|root,COG3267@2|Bacteria,1NIIA@1224|Proteobacteria,1T395@1236|Gammaproteobacteria,1XV5F@135623|Vibrionales 135623|Vibrionales U Type II secretion system protein B - - - ko:K02451 - M00331 - - ko00000,ko00002,ko02044 9.B.42 - - T2SSB k141_26300_4 1116375.VEJY3_01880 2.29e-126 361.0 COG3103@1|root,COG4991@2|Bacteria,1MX7M@1224|Proteobacteria,1RS74@1236|Gammaproteobacteria,1XUUZ@135623|Vibrionales 135623|Vibrionales T SH3 domain protein htrG - - ko:K07184 - - - - ko00000 - - - SH3_3 k141_26300_5 1051646.VITU9109_03535 7.79e-281 770.0 COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,1RP0Q@1236|Gammaproteobacteria,1XU56@135623|Vibrionales 135623|Vibrionales P COG0306 Phosphate sulphate permeases pitA - - ko:K03306 - - - - ko00000 2.A.20 - - PHO4 k141_26300_6 674977.VMC_29150 1.55e-154 434.0 COG1392@1|root,COG1392@2|Bacteria,1MXY9@1224|Proteobacteria,1RQHT@1236|Gammaproteobacteria,1XU69@135623|Vibrionales 135623|Vibrionales P COG1392 Phosphate transport regulator (distant homolog of PhoU) - - - ko:K07220 - - - - ko00000 - - - PhoU_div k141_26300_7 1116375.VEJY3_01895 0.0 937.0 COG3025@1|root,COG3025@2|Bacteria,1MY43@1224|Proteobacteria,1RMP4@1236|Gammaproteobacteria,1XSYB@135623|Vibrionales 135623|Vibrionales S CYTH ygiF - 3.6.1.25 ko:K18446 - - - - ko00000,ko01000 - - - CHAD,CYTH k141_26300_8 223926.28805405 7.76e-224 627.0 COG0840@1|root,COG0840@2|Bacteria,1R9QT@1224|Proteobacteria,1RRT3@1236|Gammaproteobacteria,1XT29@135623|Vibrionales 135623|Vibrionales NT methyl-accepting chemotaxis protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - MCPsignal k141_26300_9 1116375.VEJY3_01910 0.0 1758.0 COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,1RP9N@1236|Gammaproteobacteria,1XSHU@135623|Vibrionales 135623|Vibrionales H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell glnE GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006521,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008882,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0010565,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019752,GO:0031323,GO:0033238,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0071704,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.42,2.7.7.89 ko:K00982 - - - - ko00000,ko01000 - - - GlnD_UR_UTase,GlnE k141_26300_10 1280001.BAOA01000021_gene882 0.0 902.0 COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,1MV3Z@1224|Proteobacteria,1RMAJ@1236|Gammaproteobacteria,1XV30@135623|Vibrionales 135623|Vibrionales H Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose hldE - 2.7.1.167,2.7.7.70 ko:K03272 ko00540,ko01100,map00540,map01100 M00064 R05644,R05646 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CTP_transf_like,PfkB k141_26300_11 223926.28805408 2.96e-264 730.0 COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,1RQQV@1236|Gammaproteobacteria,1XT4C@135623|Vibrionales 135623|Vibrionales MU COG1538 Outer membrane protein tolC GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - ko:K12340 ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133 M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko02044 1.B.17,2.A.6.2 - - OEP k141_26300_12 1116375.VEJY3_01925 1.27e-136 388.0 COG0494@1|root,COG0494@2|Bacteria,1RDMW@1224|Proteobacteria,1RPZV@1236|Gammaproteobacteria,1XUUC@135623|Vibrionales 135623|Vibrionales L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes nudF - 3.6.1.13 ko:K01515 ko00230,map00230 - R01054 RC00002 ko00000,ko00001,ko01000 - - - NUDIX k141_26300_13 1116375.VEJY3_01930 3.45e-101 293.0 COG3151@1|root,COG3151@2|Bacteria,1RA4E@1224|Proteobacteria,1S55I@1236|Gammaproteobacteria,1Y2PC@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF1249) yqiB - - ko:K09920 - - - - ko00000 - - - DUF1249 k141_26300_14 1116375.VEJY3_01935 1.44e-184 514.0 COG1409@1|root,COG1409@2|Bacteria,1MWKX@1224|Proteobacteria,1RPA7@1236|Gammaproteobacteria,1XTA7@135623|Vibrionales 135623|Vibrionales S Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes cpdA - 3.1.4.53 ko:K03651 ko00230,ko02025,map00230,map02025 - R00191 RC00296 ko00000,ko00001,ko01000 - - - Metallophos k141_15611_1 1121091.AUMP01000007_gene1036 9.83e-56 187.0 COG0515@1|root,COG0515@2|Bacteria,1UZEH@1239|Firmicutes,4IPW7@91061|Bacilli 91061|Bacilli KLT RIO1 family - - 2.7.11.1 ko:K08884 - - - - ko00000,ko01000,ko01001 - - - Pkinase k141_15611_2 218284.CCDN010000001_gene1226 9.15e-150 425.0 COG4326@1|root,COG4326@2|Bacteria,1TPEA@1239|Firmicutes,4HBPW@91061|Bacilli,1ZBFU@1386|Bacillus 91061|Bacilli S COG4326 Sporulation control protein spo0M - - ko:K06377 - - - - ko00000 - - - Spo0M k141_35757_1 218284.CCDN010000001_gene1603 1.9e-112 333.0 COG2271@1|root,COG2271@2|Bacteria,1UIWI@1239|Firmicutes,4ISUR@91061|Bacilli,1ZS6G@1386|Bacillus 91061|Bacilli G Major Facilitator Superfamily - - - ko:K08152 - - - - ko00000,ko02000 2.A.1.2 - - MFS_1 k141_6099_2 218284.CCDN010000001_gene764 1.88e-66 204.0 COG2010@1|root,COG2010@2|Bacteria,1VBJT@1239|Firmicutes,4HKX4@91061|Bacilli,1ZQNJ@1386|Bacillus 91061|Bacilli C Cytochrome C oxidase, cbb3-type, subunit III cccA - - ko:K13300 - - - - ko00000 - - - Cytochrome_CBB3 k141_7240_1 218284.CCDN010000001_gene200 8.1e-135 396.0 COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,4H9VD@91061|Bacilli,1ZAU2@1386|Bacillus 91061|Bacilli G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) ptsI GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0051179,GO:0051234,GO:0071702 2.7.3.9 ko:K08483 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 8.A.7 - - PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C k141_21563_2 1124983.PFLCHA0_c03110 1.11e-73 232.0 COG1088@1|root,COG1088@2|Bacteria,1MU5E@1224|Proteobacteria,1RP7G@1236|Gammaproteobacteria,1YN85@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily rfbB - 4.2.1.46 ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 M00793 R06513 RC00402 ko00000,ko00001,ko00002,ko01000 - - - GDP_Man_Dehyd k141_9615_1 218284.CCDN010000007_gene3826 5.32e-139 409.0 COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HA52@91061|Bacilli,1ZCQI@1386|Bacillus 91061|Bacilli T Histidine kinase vicK - 2.7.13.3 ko:K07652 ko02020,map02020 M00459 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,PAS,PAS_9 k141_16741_1 218284.CCDN010000002_gene2829 6e-70 215.0 COG0778@1|root,COG0778@2|Bacteria,1V1PI@1239|Firmicutes,4HB7V@91061|Bacilli,1ZBI6@1386|Bacillus 91061|Bacilli C nitroreductase frp - - - - - - - - - - iYO844.BSU07830 Nitroreductase k141_20299_1 1280947.HY30_01150 1.69e-14 78.2 COG1629@1|root,COG4771@2|Bacteria,1N6JG@1224|Proteobacteria,2TSK9@28211|Alphaproteobacteria,43WCB@69657|Hyphomonadaceae 28211|Alphaproteobacteria P Outer membrane receptor - - - - - - - - - - - - CarboxypepD_reg,Plug,TonB_dep_Rec k141_25058_1 218284.CCDN010000001_gene942 1.13e-217 609.0 COG1003@1|root,COG1003@2|Bacteria,1TPK9@1239|Firmicutes,4HB80@91061|Bacilli,1ZATI@1386|Bacillus 91061|Bacilli E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor gcvPB - 1.4.4.2 ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 - R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko01000 - - - GDC-P k141_3710_1 218284.CCDN010000001_gene267 1.57e-189 530.0 28IBV@1|root,2Z8EA@2|Bacteria,1TPCJ@1239|Firmicutes,4HCFQ@91061|Bacilli,1ZQPV@1386|Bacillus 91061|Bacilli S YIEGIA protein - - - ko:K05739 - - - - ko00000 - - - YIEGIA k141_3710_2 218284.CCDN010000001_gene266 7.36e-36 121.0 2C579@1|root,3323N@2|Bacteria,1VJ9R@1239|Firmicutes,4IKZS@91061|Bacilli,1ZII2@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_165_1 1453501.JELR01000001_gene2040 1.27e-106 322.0 COG0438@1|root,COG0438@2|Bacteria,1RKCN@1224|Proteobacteria,1S4CE@1236|Gammaproteobacteria,46BAR@72275|Alteromonadaceae 1236|Gammaproteobacteria M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 k141_26302_1 218284.CCDN010000002_gene2063 5.02e-137 395.0 COG4129@1|root,COG4129@2|Bacteria,1UY2G@1239|Firmicutes,4HAWK@91061|Bacilli,1ZBAR@1386|Bacillus 91061|Bacilli S Aromatic acid exporter family member 1 - - - - - - - - - - - - ArAE_1 k141_34606_1 1116375.VEJY3_15926 1.08e-97 287.0 COG1284@1|root,COG1284@2|Bacteria,1RDIV@1224|Proteobacteria,1RSIN@1236|Gammaproteobacteria,1XT16@135623|Vibrionales 135623|Vibrionales S Uncharacterised 5xTM membrane BCR, YitT family COG1284 - - - - - - - - - - - - YitT_membrane k141_34606_2 223926.28808184 3.12e-103 299.0 COG0350@1|root,COG0350@2|Bacteria,1N2YQ@1224|Proteobacteria,1S68H@1236|Gammaproteobacteria,1XX26@135623|Vibrionales 135623|Vibrionales H Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated ogt - 2.1.1.63 ko:K00567,ko:K10778 - - - - ko00000,ko01000,ko03000,ko03400 - - - DNA_binding_1,HTH_18,Methyltransf_1N k141_8636_1 223926.28809856 1.78e-179 504.0 COG2304@1|root,COG2304@2|Bacteria,1MXQ7@1224|Proteobacteria,1RMDX@1236|Gammaproteobacteria,1XU2A@135623|Vibrionales 135623|Vibrionales S protein containing a von Willebrand factor type A (vWA) domain - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - VWA k141_8636_2 223926.28809855 1.37e-96 282.0 2C5QF@1|root,331W9@2|Bacteria,1N7AE@1224|Proteobacteria,1SCH2@1236|Gammaproteobacteria,1XXHT@135623|Vibrionales 135623|Vibrionales S Domain of unknown function (DUF4381) - - - - - - - - - - - - DUF4381 k141_8636_3 1116375.VEJY3_23296 5.03e-189 528.0 COG1721@1|root,COG1721@2|Bacteria,1Q7RR@1224|Proteobacteria,1RNNP@1236|Gammaproteobacteria,1XSBV@135623|Vibrionales 135623|Vibrionales S conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - - - - - - - - - - DUF58 k141_8636_4 1116375.VEJY3_23291 2.1e-218 603.0 COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,1RN5G@1236|Gammaproteobacteria,1XURM@135623|Vibrionales 135623|Vibrionales S COG0714 MoxR-like ATPases - - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 k141_8636_5 1219076.N646_3167 1.1e-32 114.0 2AWN1@1|root,31NIT@2|Bacteria,1QK9F@1224|Proteobacteria,1TICX@1236|Gammaproteobacteria,1XYW9@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_8636_6 223926.28809815 1.59e-115 335.0 COG2197@1|root,COG2197@2|Bacteria,1MXI3@1224|Proteobacteria,1SRVN@1236|Gammaproteobacteria,1Y2F3@135623|Vibrionales 135623|Vibrionales K helix_turn_helix, Lux Regulon - - - ko:K20918 ko05111,map05111 - - - ko00000,ko00001,ko03000 - - - GerE k141_8636_7 223926.28809814 2.06e-117 340.0 COG2197@1|root,COG2197@2|Bacteria,1MXI3@1224|Proteobacteria,1RNEY@1236|Gammaproteobacteria,1XUE2@135623|Vibrionales 135623|Vibrionales K helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE k141_8636_8 1219076.N646_3164 7.46e-38 136.0 COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,1RNK8@1236|Gammaproteobacteria,1XXRR@135623|Vibrionales 135623|Vibrionales Q Haemolysin-type calcium-binding repeat (2 copies) - - - - - - - - - - - - HemolysinCabind k141_8636_9 223926.28809812 1.88e-70 228.0 COG4618@1|root,COG4618@2|Bacteria,1NTI5@1224|Proteobacteria,1T1HR@1236|Gammaproteobacteria,1XUAM@135623|Vibrionales 135623|Vibrionales V COG4618 ABC-type protease lipase transport system, ATPase and permease components - - - ko:K06148 - - - - ko00000,ko02000 3.A.1 - - ABC_membrane,ABC_tran k141_37094_1 1453501.JELR01000001_gene2827 9.34e-55 189.0 COG1538@1|root,COG1538@2|Bacteria,1MYX2@1224|Proteobacteria,1RYIR@1236|Gammaproteobacteria,46CEK@72275|Alteromonadaceae 1236|Gammaproteobacteria MU Outer membrane efflux protein - - - ko:K12543 - M00330 - - ko00000,ko00002,ko02000,ko02044 1.B.17,3.A.1.109.4 - - OEP k141_31249_2 218284.CCDN010000001_gene679 4.76e-103 305.0 arCOG13259@1|root,2ZCJ1@2|Bacteria,1V55Y@1239|Firmicutes,4IS41@91061|Bacilli,1ZS10@1386|Bacillus 91061|Bacilli E Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links tgl - 2.3.2.13 ko:K00686 - - - - ko00000,ko01000 - - - - k141_5061_1 1453501.JELR01000002_gene591 1.61e-51 176.0 COG3047@1|root,COG3047@2|Bacteria,1NUZJ@1224|Proteobacteria,1RRRC@1236|Gammaproteobacteria,467CK@72275|Alteromonadaceae 1236|Gammaproteobacteria M Outer membrane protein W ompW - - ko:K07275 - - - - ko00000 - - - OmpW k141_3953_1 1298865.H978DRAFT_1314 1.19e-46 159.0 COG1403@1|root,COG1403@2|Bacteria,1NI19@1224|Proteobacteria,1SIZN@1236|Gammaproteobacteria 1236|Gammaproteobacteria V HNH endonuclease - - - - - - - - - - - - HNH k141_3953_3 314278.NB231_00015 2.26e-24 99.8 2AGS6@1|root,31703@2|Bacteria,1RJ9H@1224|Proteobacteria,1SKFX@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_26638_1 617140.AJZE01000048_gene3201 5.73e-80 244.0 COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,1RP1T@1236|Gammaproteobacteria,1XTX0@135623|Vibrionales 135623|Vibrionales J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus fmt GO:0003674,GO:0003824,GO:0004479,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006418,GO:0006431,GO:0006464,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019752,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 ko:K00604 ko00670,ko00970,map00670,map00970 - R03940 RC00026,RC00165 ko00000,ko00001,ko01000 - - - Formyl_trans_C,Formyl_trans_N k141_26638_2 674977.VMC_24990 3.97e-112 324.0 COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,1S247@1236|Gammaproteobacteria,1XSD0@135623|Vibrionales 135623|Vibrionales J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions def GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008463,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 ko:K01462 - - - - ko00000,ko01000 - - - Pep_deformylase k141_26638_3 1116375.VEJY3_15315 3.87e-142 408.0 COG1652@1|root,COG1652@2|Bacteria,1MUBV@1224|Proteobacteria,1RPMB@1236|Gammaproteobacteria,1XUKE@135623|Vibrionales 135623|Vibrionales C protein containing LysM domain - - - - - - - - - - - - LysM k141_12297_1 1042377.AFPJ01000022_gene1304 1.24e-124 367.0 COG2223@1|root,COG2223@2|Bacteria,1MU27@1224|Proteobacteria,1RP5H@1236|Gammaproteobacteria,4651E@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG2223 Nitrate nitrite transporter - - - ko:K02575 ko00910,map00910 M00615 - - ko00000,ko00001,ko00002,ko02000 2.A.1.8 - - MFS_1 k141_21728_1 1444310.JANV01000064_gene1972 2.15e-44 152.0 COG1989@1|root,COG1989@2|Bacteria,1TQY4@1239|Firmicutes,4HCC3@91061|Bacilli,1ZCQ2@1386|Bacillus 91061|Bacilli NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases comC - 3.4.23.43 ko:K02236,ko:K02654 - M00331,M00429 - - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 3.A.15.2 - - DiS_P_DiS,Peptidase_A24 k141_21728_2 218284.CCDN010000001_gene619 1.36e-15 75.5 COG4972@1|root,COG4972@2|Bacteria,1TSTG@1239|Firmicutes,4HFQU@91061|Bacilli,1ZC5N@1386|Bacillus 91061|Bacilli NU COG4972 Tfp pilus assembly protein, ATPase PilM - - - ko:K02662,ko:K02663 - - - - ko00000,ko02035,ko02044 - - - PilM_2 k141_6378_1 1116375.VEJY3_20306 4.98e-94 276.0 COG2847@1|root,COG2847@2|Bacteria,1MZ3M@1224|Proteobacteria,1SCJD@1236|Gammaproteobacteria,1XXAS@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria - - - ko:K09796 - - - - ko00000,ko03110 - - - PCuAC k141_2741_2 218284.CCDN010000012_gene4447 4.4e-142 400.0 COG0353@1|root,COG0353@2|Bacteria,1TR87@1239|Firmicutes,4HAZR@91061|Bacilli,1ZBDK@1386|Bacillus 91061|Bacilli L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO recR - - ko:K06187 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecR,Toprim_4 k141_8670_1 1205908.AKXW01000108_gene1242 1.71e-158 476.0 COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,1SP6I@1236|Gammaproteobacteria,1XUED@135623|Vibrionales 135623|Vibrionales P Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family cusA - - ko:K07787 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.6.1.4 - - ACR_tran k141_6403_1 1042377.AFPJ01000025_gene587 1.13e-12 65.5 COG1546@1|root,COG1546@2|Bacteria,1RH2Y@1224|Proteobacteria,1S5WH@1236|Gammaproteobacteria,4677Y@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the CinA family ygaD GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016811,GO:0019159 3.5.1.42 ko:K03743 ko00760,map00760 - R02322 RC00100 ko00000,ko00001,ko01000 - - - CinA k141_6403_2 469383.Cwoe_0197 2.71e-22 95.1 COG2030@1|root,COG2030@2|Bacteria,2GNQQ@201174|Actinobacteria,4CS7Q@84995|Rubrobacteria 84995|Rubrobacteria I MaoC like domain - - - - - - - - - - - - MaoC_dehydratas k141_14574_1 1247963.JPHU01000001_gene1799 5e-05 51.2 COG1629@1|root,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,2TS4W@28211|Alphaproteobacteria 28211|Alphaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec k141_12335_1 42565.FP66_02055 1e-12 62.8 COG2747@1|root,COG2747@2|Bacteria,1NGJA@1224|Proteobacteria,1SY5P@1236|Gammaproteobacteria,1XQF1@135619|Oceanospirillales 135619|Oceanospirillales KNU Anti-sigma-28 factor, FlgM flgM - - ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 - - - ko00000,ko00001,ko02035 - - - FlgM k141_12335_2 42565.FP66_02050 2.15e-59 188.0 COG1261@1|root,COG1261@2|Bacteria,1NY6E@1224|Proteobacteria,1RMY1@1236|Gammaproteobacteria 1236|Gammaproteobacteria N Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly flgA - - ko:K02386 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - ChapFlgA k141_11026_1 1308866.J416_09449 1.62e-55 177.0 2B6C2@1|root,31Z9P@2|Bacteria,1V8WP@1239|Firmicutes,4HJX5@91061|Bacilli,471UW@74385|Gracilibacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_22978_1 1121938.AUDY01000009_gene2364 2.51e-116 351.0 COG2015@1|root,COG2015@2|Bacteria,1TR7Q@1239|Firmicutes,4HIVI@91061|Bacilli 91061|Bacilli Q Alkyl sulfatase dimerisation sepA - - - - - - - - - - - Alkyl_sulf_C,Alkyl_sulf_dimr,Lactamase_B k141_440_1 1116375.VEJY3_07410 2.46e-42 139.0 2AWUG@1|root,31NRR@2|Bacteria,1QKG0@1224|Proteobacteria,1TIK1@1236|Gammaproteobacteria,1XZ9E@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_440_2 1116375.VEJY3_07405 4.2e-28 102.0 2AWVK@1|root,31NSZ@2|Bacteria,1QKH7@1224|Proteobacteria,1TIMC@1236|Gammaproteobacteria,1XZBV@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_26670_1 314265.R2601_10709 1.47e-56 184.0 COG0411@1|root,COG0411@2|Bacteria,1MXHT@1224|Proteobacteria,2TSWS@28211|Alphaproteobacteria 28211|Alphaproteobacteria E COG0411 ABC-type branched-chain amino acid transport systems ATPase component - - - ko:K01995 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C k141_9846_1 218284.CCDN010000005_gene3247 4.39e-197 559.0 COG0366@1|root,COG0366@2|Bacteria,1TNZ0@1239|Firmicutes,4HB67@91061|Bacilli,1ZAZP@1386|Bacillus 91061|Bacilli G Alpha amylase, N-terminal ig-like domain nplT - 3.2.1.133,3.2.1.135,3.2.1.54 ko:K01208 ko00500,ko01100,map00500,map01100 - R02112,R03122,R11262 - ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,Alpha-amylase_N,Malt_amylase_C k141_35942_1 1444310.JANV01000148_gene4232 1.7e-311 856.0 COG3666@1|root,COG3666@2|Bacteria,1TQQ9@1239|Firmicutes,4H9KK@91061|Bacilli,1ZCCI@1386|Bacillus 91061|Bacilli L Transposase domain (DUF772) - - - - - - - - - - - - DDE_Tnp_1,DDE_Tnp_1_6,DUF772 k141_1478_1 997296.PB1_16919 5.16e-118 340.0 COG2220@1|root,COG2220@2|Bacteria,1TQR1@1239|Firmicutes,4HBM0@91061|Bacilli,1ZBI0@1386|Bacillus 91061|Bacilli S Belongs to the UPF0173 family ytkL - - - - - - - - - - - Lactamase_B_2,Lactamase_B_3 k141_5093_1 1122139.KB907862_gene553 3.83e-193 546.0 COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,1S0TI@1236|Gammaproteobacteria,1XPWD@135619|Oceanospirillales 135619|Oceanospirillales E Bacterial extracellular solute-binding proteins, family 5 Middle - - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 k141_19339_1 1453501.JELR01000002_gene1080 2.55e-175 507.0 COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,1RMAH@1236|Gammaproteobacteria,4648F@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0339 Zn-dependent oligopeptidases prlC GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006465,GO:0006508,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0034645,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051604,GO:0070011,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564,GO:1901576 3.4.24.70 ko:K01414 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M3 k141_28894_1 314271.RB2654_08177 2.4e-102 324.0 COG1216@1|root,COG1216@2|Bacteria,1MZBS@1224|Proteobacteria,2UEUD@28211|Alphaproteobacteria 28211|Alphaproteobacteria S N-terminal domain of galactosyltransferase - - - - - - - - - - - - Glyco_transf_7C k141_25308_1 218284.CCDN010000002_gene2274 2.45e-27 111.0 COG0488@1|root,COG0488@2|Bacteria,1TQNA@1239|Firmicutes,4H9VW@91061|Bacilli,1ZBZP@1386|Bacillus 91061|Bacilli S ABC transporter expZ - - ko:K18231 ko02010,map02010 - - - br01600,ko00000,ko00001,ko01504,ko02000 3.A.1.121.1,3.A.1.121.3 - - ABC_tran,ABC_tran_Xtn k141_11027_1 402777.KB235903_gene1492 1e-23 102.0 COG3264@1|root,COG3264@2|Bacteria,1G2UD@1117|Cyanobacteria,1H8A1@1150|Oscillatoriales 1117|Cyanobacteria M mechanosensitive ion channel - - - - - - - - - - - - MS_channel k141_11027_2 35703.DQ02_02840 3.54e-06 48.1 COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,1RQ59@1236|Gammaproteobacteria,3WWUC@544|Citrobacter 1236|Gammaproteobacteria E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline argF GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3,2.1.3.9 ko:K00611,ko:K09065 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01398,R07245 RC00096 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N k141_29970_1 218284.CCDN010000001_gene1828 3.42e-171 489.0 COG0621@1|root,COG0621@2|Bacteria,1TNYN@1239|Firmicutes,4HAAS@91061|Bacilli,1ZBMF@1386|Bacillus 91061|Bacilli J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine miaB GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035597,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360 2.8.4.3 ko:K06168 - - R10645,R10646,R10647 RC00003,RC00980,RC03221,RC03222 ko00000,ko01000,ko03016 - - - Radical_SAM,TRAM,UPF0004 k141_9847_1 1540221.JQNI01000002_gene1227 3.27e-08 58.5 COG0589@1|root,COG0589@2|Bacteria,1WJVG@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus T Universal stress protein - - - - - - - - - - - - Usp k141_20480_1 218284.CCDN010000002_gene2114 9.3e-142 407.0 COG3508@1|root,COG3508@2|Bacteria,1UYZ0@1239|Firmicutes,4HCCC@91061|Bacilli,1ZC6Q@1386|Bacillus 91061|Bacilli Q homogentisate 12-dioxygenase hmgA - 1.13.11.5 ko:K00451 ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120 M00044 R02519 RC00737 ko00000,ko00001,ko00002,ko01000 - - - HgmA k141_20480_2 218284.CCDN010000002_gene2113 1.14e-171 483.0 COG0179@1|root,COG0179@2|Bacteria,1UY98@1239|Firmicutes,4HC89@91061|Bacilli,1ZCD1@1386|Bacillus 91061|Bacilli Q Fumarylacetoacetate (FAA) hydrolase family - - 3.7.1.2 ko:K16171 ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120 M00044 R01364 RC00326,RC00446 ko00000,ko00001,ko00002,ko01000 - - - FAA_hydrolase k141_8672_1 218284.CCDN010000008_gene4257 8.2e-69 218.0 COG0701@1|root,COG0701@2|Bacteria,1TQHK@1239|Firmicutes,4HB25@91061|Bacilli,1ZC03@1386|Bacillus 91061|Bacilli S permeases - - - ko:K07089 - - - - ko00000 - - - ArsP_1 k141_25309_1 935837.JAEK01000001_gene2161 1.2e-36 132.0 COG1555@1|root,COG1555@2|Bacteria,1VA3W@1239|Firmicutes,4HKJ1@91061|Bacilli,1ZH4N@1386|Bacillus 91061|Bacilli L COG1555 DNA uptake protein and related DNA-binding proteins comEA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02237 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - HHH_3,SLBB k141_5094_1 1042377.AFPJ01000019_gene2537 1.53e-35 134.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RNBD@1236|Gammaproteobacteria,46642@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec k141_19340_1 1042377.AFPJ01000009_gene234 6.37e-36 134.0 COG0668@1|root,COG0668@2|Bacteria,1QU7U@1224|Proteobacteria,1T2B5@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Mechanosensitive ion channel - - - - - - - - - - - - MS_channel k141_13489_1 218284.CCDN010000002_gene2159 3.92e-141 403.0 COG1175@1|root,COG1175@2|Bacteria,1TS63@1239|Firmicutes,4HECA@91061|Bacilli,1ZBSI@1386|Bacillus 91061|Bacilli G Binding-protein-dependent transport system inner membrane component - - - ko:K02025 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - BPD_transp_1 k141_9848_1 1294265.JCM21738_4129 6.02e-107 311.0 COG0208@1|root,COG0208@2|Bacteria,1TQTH@1239|Firmicutes,4H9WX@91061|Bacilli,1ZBBM@1386|Bacillus 91061|Bacilli F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdB - 1.17.4.1 ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_sm k141_9848_2 1294265.JCM21738_4123 4.04e-48 158.0 COG0110@1|root,COG0110@2|Bacteria,1TQEX@1239|Firmicutes,4HAJ0@91061|Bacilli,1ZDPK@1386|Bacillus 91061|Bacilli S COG0110 Acetyltransferase (isoleucine patch superfamily) maa - 2.3.1.79 ko:K00661 - - - - ko00000,ko01000 - - - CM_2,Hexapep,Hexapep_2,Mac k141_26672_2 218284.CCDN010000005_gene3235 1.99e-38 129.0 2DPJX@1|root,332FH@2|Bacteria,1VF9T@1239|Firmicutes,4HPCA@91061|Bacilli,1ZIV2@1386|Bacillus 91061|Bacilli S Spore germination protein gerPA GO:0000003,GO:0008150,GO:0009847,GO:0019954,GO:0030436,GO:0032502,GO:0043934 - ko:K06299 - - - - ko00000 - - - gerPA k141_26672_3 1340434.AXVA01000002_gene1273 1.38e-21 87.0 2EBHF@1|root,335HY@2|Bacteria,1VHMW@1239|Firmicutes,4HPZZ@91061|Bacilli,1ZIW2@1386|Bacillus 91061|Bacilli S cell differentiation gerPB - - ko:K06300 - - - - ko00000 - - - GerPB k141_12338_1 1042377.AFPJ01000024_gene739 4.26e-115 337.0 COG2084@1|root,COG2084@2|Bacteria,1RA7F@1224|Proteobacteria,1RMMY@1236|Gammaproteobacteria,464MY@72275|Alteromonadaceae 1236|Gammaproteobacteria I Belongs to the 3-hydroxyisobutyrate dehydrogenase family mmsB - 1.1.1.31 ko:K00020 ko00280,ko01100,map00280,map01100 - R05066 RC00099 ko00000,ko00001,ko01000 - - - NAD_binding_11,NAD_binding_2 k141_21746_1 218284.CCDN010000010_gene4363 6.57e-89 266.0 COG0090@1|root,COG0090@2|Bacteria,1TP9X@1239|Firmicutes,4HAE8@91061|Bacilli,1ZCQP@1386|Bacillus 91061|Bacilli J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity rplB GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02886 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L2,Ribosomal_L2_C k141_21746_2 218284.CCDN010000010_gene4362 2.95e-62 190.0 COG0185@1|root,COG0185@2|Bacteria,1V6CX@1239|Firmicutes,4HIG0@91061|Bacilli,1ZGXY@1386|Bacillus 91061|Bacilli J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA rpsS GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - ko:K02965 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S19 k141_25310_2 1453501.JELR01000001_gene2562 6.22e-11 62.4 COG2813@1|root,COG2813@2|Bacteria,1MXE9@1224|Proteobacteria,1RQCH@1236|Gammaproteobacteria,466JK@72275|Alteromonadaceae 1236|Gammaproteobacteria J Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle rsmC GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052914,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.172 ko:K00564 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - MTS,MTS_N k141_7449_1 218284.CCDN010000001_gene791 1.3e-21 91.3 COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,4HAB1@91061|Bacilli,1ZBQ5@1386|Bacillus 91061|Bacilli P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system pstBA - 3.6.3.27 ko:K02036 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 - - ABC_tran k141_7449_2 218284.CCDN010000001_gene790 9.96e-113 329.0 COG0581@1|root,COG0581@2|Bacteria,1TP74@1239|Firmicutes,4HAKF@91061|Bacilli,1ZDAY@1386|Bacillus 91061|Bacilli P Phosphate transport system permease pstA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02038 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 k141_443_1 626887.J057_13441 6.9e-151 446.0 COG3256@1|root,COG3256@2|Bacteria,1MVT1@1224|Proteobacteria,1RQ01@1236|Gammaproteobacteria,464BD@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG3256 Nitric oxide reductase large subunit norB - 1.7.2.5 ko:K04561 ko00910,ko01120,map00910,map01120 M00529 R00294 RC02794 ko00000,ko00001,ko00002,ko01000 3.D.4.10 - - COX1 k141_5095_2 1042377.AFPJ01000012_gene1378 1.23e-46 150.0 COG3529@1|root,COG3529@2|Bacteria,1NPXJ@1224|Proteobacteria,1SHB8@1236|Gammaproteobacteria,4696D@72275|Alteromonadaceae 1236|Gammaproteobacteria S nucleic-acid-binding protein containing a Zn-ribbon domain - - - ko:K07070 - - - - ko00000 - - - DUF2387 k141_18230_1 1294265.JCM21738_4180 1.15e-114 336.0 COG0364@1|root,COG0364@2|Bacteria,1TPYF@1239|Firmicutes,4HA73@91061|Bacilli,1ZCZ3@1386|Bacillus 91061|Bacilli G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone zwf - 1.1.1.363,1.1.1.49 ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 M00004,M00006,M00008 R00835,R02736,R10907 RC00001,RC00066 ko00000,ko00001,ko00002,ko01000,ko04147 - - - G6PD_C,G6PD_N k141_3989_1 870967.VIS19158_03906 3.94e-71 218.0 2DMPB@1|root,32SV8@2|Bacteria,1NHUE@1224|Proteobacteria,1SIKI@1236|Gammaproteobacteria,1XY3E@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_3989_3 675812.VHA_000297 5.3e-20 84.0 2AXH3@1|root,31PGS@2|Bacteria,1QM6H@1224|Proteobacteria,1TJEF@1236|Gammaproteobacteria,1Y13Z@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_3989_4 1136163.M565_ctg5P0932 1.66e-25 97.4 2DQ5J@1|root,334UR@2|Bacteria,1N8UA@1224|Proteobacteria,1TF4A@1236|Gammaproteobacteria,1XZAU@135623|Vibrionales 135623|Vibrionales S Phage tail assembly chaperone - - - - - - - - - - - - Phage_TAC_10 k141_3989_5 1136163.M565_ctg5P0930 1.14e-256 731.0 COG5283@1|root,COG5283@2|Bacteria,1P1DE@1224|Proteobacteria,1THI8@1236|Gammaproteobacteria,1XW2E@135623|Vibrionales 135623|Vibrionales S Phage-related minor tail protein - - - - - - - - - - - - PhageMin_Tail k141_3989_6 1136163.M565_ctg5P0929 7.34e-50 160.0 2E46B@1|root,32Z29@2|Bacteria,1RHDP@1224|Proteobacteria,1S81B@1236|Gammaproteobacteria,1XYKD@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF2590) - - - - - - - - - - - - DUF2590 k141_3989_7 1454202.PPBDW_100344___1 3.4e-191 541.0 COG3299@1|root,COG3299@2|Bacteria,1PEAH@1224|Proteobacteria,1RPNV@1236|Gammaproteobacteria,1XVEG@135623|Vibrionales 135623|Vibrionales S Baseplate J-like protein - - - - - - - - - - - - Baseplate_J k141_3989_8 1454202.PPBDW_100343___1 5.27e-73 226.0 2B8M4@1|root,321WF@2|Bacteria,1RHPZ@1224|Proteobacteria,1S6AB@1236|Gammaproteobacteria,1XW1E@135623|Vibrionales 135623|Vibrionales S Phage tail protein (Tail_P2_I) - - - - - - - - - - - - Tail_P2_I k141_3989_9 1454202.PPBDW_100342___1 3.67e-105 353.0 COG5301@1|root,COG5301@2|Bacteria,1N4KH@1224|Proteobacteria,1RXZU@1236|Gammaproteobacteria,1XW3K@135623|Vibrionales 135623|Vibrionales S Phage tail-collar fibre protein - - - - - - - - - - - - DUF3751 k141_3989_10 1136163.M565_ctg5P0923 6.88e-86 257.0 2EDZ9@1|root,337U1@2|Bacteria,1N8NP@1224|Proteobacteria,1S2GG@1236|Gammaproteobacteria,1XXH4@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_3989_11 1454202.PPBDW_100340___1 3.37e-26 102.0 COG3501@1|root,COG3501@2|Bacteria,1RI4Z@1224|Proteobacteria,1S716@1236|Gammaproteobacteria,1XWKJ@135623|Vibrionales 135623|Vibrionales S Rhs element vgr protein - - - - - - - - - - - - - k141_37117_1 1132442.KB889752_gene2871 6.52e-22 91.7 COG0118@1|root,COG0118@2|Bacteria,1TQT0@1239|Firmicutes,4HFXQ@91061|Bacilli,1ZBC4@1386|Bacillus 91061|Bacilli E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR hisH GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - - GATase k141_37117_2 218284.CCDN010000006_gene3639 4.18e-154 435.0 COG0106@1|root,COG0106@2|Bacteria,1V1IR@1239|Firmicutes,4HACP@91061|Bacilli,1ZC7D@1386|Bacillus 91061|Bacilli E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase hisA GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04640 RC00945 ko00000,ko00001,ko00002,ko01000 - - - His_biosynth k141_24093_2 935948.KE386494_gene46 2.86e-16 77.8 COG4186@1|root,COG4186@2|Bacteria,1V6DG@1239|Firmicutes,24JMS@186801|Clostridia 186801|Clostridia S Phosphoesterase - - - - - - - - - - - - Metallophos k141_25311_1 1071073.KI530549_gene3537 4.16e-08 55.8 COG0707@1|root,COG0707@2|Bacteria,1TQFT@1239|Firmicutes,4HBAQ@91061|Bacilli,1ZBA5@1386|Bacillus 91061|Bacilli M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) murG - 2.4.1.227 ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 - R05032,R05662 RC00005,RC00049 ko00000,ko00001,ko01000,ko01011 - GT28 - Glyco_tran_28_C,Glyco_transf_28 k141_22979_2 1042377.AFPJ01000048_gene2685 2.2e-210 622.0 COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,1RSKR@1236|Gammaproteobacteria,46CIZ@72275|Alteromonadaceae 1236|Gammaproteobacteria KLT Lipopolysaccharide kinase (Kdo/WaaP) family - - 2.7.11.1 ko:K08884,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - Pkinase,TPR_16,TPR_19,TPR_2,TPR_8 k141_11030_1 112098.XP_008620940.1 2.57e-116 347.0 COG0076@1|root,KOG0629@2759|Eukaryota 2759|Eukaryota E carboxy-lyase activity - - 4.1.1.22 ko:K01590 ko00340,ko01100,ko01110,map00340,map01100,map01110 - R01167 RC00299 ko00000,ko00001,ko01000 - - - Pyridoxal_deC k141_2745_1 42565.FP66_12945 1.76e-34 117.0 COG0333@1|root,COG0333@2|Bacteria,1N6RF@1224|Proteobacteria,1SC9G@1236|Gammaproteobacteria,1XM5T@135619|Oceanospirillales 135619|Oceanospirillales J Belongs to the bacterial ribosomal protein bL32 family rpmF - - ko:K02911 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_L32p k141_2745_2 42565.FP66_12950 4.29e-72 219.0 COG1399@1|root,COG1399@2|Bacteria,1PGKW@1224|Proteobacteria,1RRK3@1236|Gammaproteobacteria,1XJKJ@135619|Oceanospirillales 135619|Oceanospirillales S metal-binding, possibly nucleic acid-binding protein - - - ko:K07040 - - - - ko00000 - - - DUF177 k141_29972_1 471223.GWCH70_0846 2.76e-71 226.0 COG0182@1|root,COG0182@2|Bacteria,1TPDK@1239|Firmicutes,4H9WM@91061|Bacilli,1WFH8@129337|Geobacillus 91061|Bacilli E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) mtnA GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 ko:K08963 ko00270,ko01100,map00270,map01100 M00034 R04420 RC01151 ko00000,ko00001,ko00002,ko01000 - - - IF-2B k141_12339_1 1517416.IDAT_03085 1.09e-14 72.8 COG3256@1|root,COG3256@2|Bacteria,1MVT1@1224|Proteobacteria,1RQ01@1236|Gammaproteobacteria,2QGKI@267893|Idiomarinaceae 1236|Gammaproteobacteria P Cytochrome C and Quinol oxidase polypeptide I norB - 1.7.2.5 ko:K04561 ko00910,ko01120,map00910,map01120 M00529 R00294 RC02794 ko00000,ko00001,ko00002,ko01000 3.D.4.10 - - COX1 k141_37130_12 1453501.JELR01000001_gene2480 7.14e-83 255.0 COG1472@1|root,COG1472@2|Bacteria,1MVAJ@1224|Proteobacteria,1RMQF@1236|Gammaproteobacteria,463YX@72275|Alteromonadaceae 1236|Gammaproteobacteria G Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides nagZ GO:0000270,GO:0003674,GO:0003824,GO:0004553,GO:0004563,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006807,GO:0008150,GO:0008152,GO:0009254,GO:0009273,GO:0009987,GO:0015929,GO:0016787,GO:0016798,GO:0030203,GO:0042546,GO:0043170,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901564 3.2.1.52 ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 M00628 R00022,R05963,R07809,R07810,R10831 RC00049 ko00000,ko00001,ko00002,ko01000 - - iSFV_1184.SFV_1127,iUMN146_1321.UM146_11790 Glyco_hydro_3 k141_8712_2 218284.CCDN010000001_gene1265 1.72e-110 322.0 COG0307@1|root,COG0307@2|Bacteria,1V1EP@1239|Firmicutes,4HC7B@91061|Bacilli,1ZBB9@1386|Bacillus 91061|Bacilli H Riboflavin synthase ribE GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9 ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00066 RC00958,RC00960 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS08950,iYO844.BSU23270 Lum_binding k141_8712_3 935836.JAEL01000088_gene4765 5.78e-24 101.0 COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1TP4F@1239|Firmicutes,4HBNA@91061|Bacilli,1ZBTJ@1386|Bacillus 91061|Bacilli H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate ribD GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0016070,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 1.1.1.193,3.5.4.26 ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 M00125 R03458,R03459 RC00204,RC00933 ko00000,ko00001,ko00002,ko01000 - - - RibD_C,dCMP_cyt_deam_1 k141_26942_2 218284.CCDN010000001_gene1858 8.35e-112 323.0 COG0558@1|root,COG0558@2|Bacteria,1V6PJ@1239|Firmicutes,4HCEX@91061|Bacilli,1ZBJ2@1386|Bacillus 91061|Bacilli I Belongs to the CDP-alcohol phosphatidyltransferase class-I family pgsA GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 2.7.8.5 ko:K00995 ko00564,ko01100,map00564,map01100 - R01801 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 - - iSB619.SA_RS06365 CDP-OH_P_transf k141_11344_1 720555.BATR1942_04415 1.15e-56 193.0 COG1524@1|root,COG1524@2|Bacteria,1TQ3C@1239|Firmicutes,4HBTH@91061|Bacilli,1ZDAI@1386|Bacillus 91061|Bacilli S proteins of the AP superfamily - - - - - - - - - - - - Phosphodiest k141_6535_1 1453501.JELR01000002_gene1178 2.95e-20 88.6 COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,1RNUF@1236|Gammaproteobacteria,464HW@72275|Alteromonadaceae 1236|Gammaproteobacteria P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system pstB - 3.6.3.27 ko:K02036 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 - - ABC_tran k141_32514_1 218284.CCDN010000005_gene3201 2.09e-103 313.0 COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HA2G@91061|Bacilli,1ZBE5@1386|Bacillus 91061|Bacilli IQ Activates fatty acids by binding to coenzyme A lcfB_2 - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding,AMP-binding_C k141_35062_1 218284.CCDN010000005_gene3289 7.31e-177 503.0 COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,4H9TI@91061|Bacilli,1ZBG7@1386|Bacillus 91061|Bacilli I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol cls GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0071704,GO:0071944,GO:0090407,GO:1901576 - ko:K06131 ko00564,ko01100,map00564,map01100 - R07390 RC00017 ko00000,ko00001,ko01000 - - - PLDc_2,PLDc_N k141_35062_2 202752.JL53_12115 1.56e-10 64.7 COG4469@1|root,COG4469@2|Bacteria,1TRGD@1239|Firmicutes,4HFP5@91061|Bacilli,26K8B@186820|Listeriaceae 91061|Bacilli S Competence protein coiA - - ko:K06198 - - - - ko00000 - - - CoiA k141_25632_3 1248232.BANQ01000151_gene4080 2.86e-07 59.3 COG3144@1|root,COG3144@2|Bacteria,1N86W@1224|Proteobacteria,1SER0@1236|Gammaproteobacteria,1XXIJ@135623|Vibrionales 135623|Vibrionales N Flagellar hook-length control protein FliK - - - ko:K02414 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_hook k141_10181_1 1337093.MBE-LCI_2279 1.81e-40 149.0 COG3307@1|root,COG3307@2|Bacteria 2|Bacteria M -O-antigen - - - - - - - - - - - - Wzy_C k141_15972_1 42565.FP66_07115 1.65e-93 283.0 COG0281@1|root,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,1RN5F@1236|Gammaproteobacteria,1XI7B@135619|Oceanospirillales 135619|Oceanospirillales C Malate dehydrogenase maeB - 1.1.1.38,1.1.1.40 ko:K00027,ko:K00029 ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020 M00169,M00172 R00214,R00216 RC00105 ko00000,ko00001,ko00002,ko01000 - - - Malic_M,malic k141_18484_2 172088.AUGA01000004_gene4056 6.47e-14 67.8 COG3791@1|root,COG3791@2|Bacteria,1N023@1224|Proteobacteria,2UC7M@28211|Alphaproteobacteria,3JZ34@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Glutathione-dependent formaldehyde-activating enzyme - - - - - - - - - - - - GFA k141_11345_1 1453501.JELR01000002_gene325 2.77e-166 491.0 COG1629@1|root,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria,4651V@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_27728_1 796606.BMMGA3_11720 2.72e-25 99.4 2E4ER@1|root,32Z9X@2|Bacteria,1VGCA@1239|Firmicutes,4HS6U@91061|Bacilli,1ZJ5Y@1386|Bacillus 91061|Bacilli - - yqzD - - - - - - - - - - - Sigma70_r4_2 k141_36099_1 1294265.JCM21738_318 1.13e-27 101.0 COG1987@1|root,COG1987@2|Bacteria,1VEHF@1239|Firmicutes,4HKVS@91061|Bacilli,1ZI12@1386|Bacillus 91061|Bacilli N Role in flagellar biosynthesis fliQ - - ko:K02420 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - Bac_export_3 k141_10182_1 218284.CCDN010000001_gene32 3.09e-112 328.0 COG1760@1|root,COG1760@2|Bacteria,1TP79@1239|Firmicutes,4HAI1@91061|Bacilli,1ZC9A@1386|Bacillus 91061|Bacilli E L-serine dehydratase sdaAA GO:0003674,GO:0003824,GO:0003941,GO:0016829,GO:0016840,GO:0016841 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 - R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 - - - SDH_alpha k141_10182_2 218284.CCDN010000001_gene33 1.61e-13 67.8 COG1760@1|root,COG1760@2|Bacteria,1U8TZ@1239|Firmicutes,4HBD6@91061|Bacilli,1ZCRK@1386|Bacillus 91061|Bacilli E L-serine dehydratase sdaAB GO:0003674,GO:0003824,GO:0003941,GO:0016829,GO:0016840,GO:0016841 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 - R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 - - - ACT,SDH_beta k141_13797_2 1042377.AFPJ01000010_gene1446 1.95e-194 545.0 COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,1RNXH@1236|Gammaproteobacteria,464XR@72275|Alteromonadaceae 1236|Gammaproteobacteria C oxidoreductases (related to aryl-alcohol dehydrogenases) tas GO:0003674,GO:0003824,GO:0004033,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016491,GO:0016614,GO:0016616,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034198,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0071496,GO:1990928 - - - - - - - - - - Aldo_ket_red k141_13797_3 1535422.ND16A_1731 1.07e-184 541.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_14742_1 1042377.AFPJ01000012_gene1349 2.25e-123 374.0 COG4772@1|root,COG4772@2|Bacteria,1MWDG@1224|Proteobacteria,1RQA5@1236|Gammaproteobacteria,464IF@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG4772 Outer membrane receptor for Fe3 -dicitrate fecA - - ko:K16091 - - - - ko00000,ko02000 1.B.14.1.14 - - Plug,TonB_dep_Rec k141_30137_1 1294265.JCM21738_5248 1.65e-100 299.0 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4H9S5@91061|Bacilli,1ZCDJ@1386|Bacillus 91061|Bacilli P COG0474 Cation transport ATPase yloB GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - iYO844.BSU15650 Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase k141_26944_1 1123517.JOMR01000001_gene385 3.86e-28 109.0 COG4665@1|root,COG4665@2|Bacteria,1RHBW@1224|Proteobacteria,1S5Y0@1236|Gammaproteobacteria,4611K@72273|Thiotrichales 72273|Thiotrichales Q TRAP-type mannitol chloroaromatic compound transport system, small permease component - - - - - - - - - - - - DctQ k141_18485_2 386043.lwe2166 2.04e-41 139.0 COG1694@1|root,COG1694@2|Bacteria,1VIQA@1239|Firmicutes,4HM6C@91061|Bacilli,26KR3@186820|Listeriaceae 91061|Bacilli S MazG nucleotide pyrophosphohydrolase domain - - - - - - - - - - - - MazG k141_19608_1 1382305.AZUC01000057_gene2056 5.07e-79 250.0 COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,4HAM7@91061|Bacilli,26CZ4@186818|Planococcaceae 91061|Bacilli E COG0747 ABC-type dipeptide transport system, periplasmic component - - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 k141_25635_1 218284.CCDN010000001_gene152 1.17e-110 330.0 COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,4HB3K@91061|Bacilli,1ZCJR@1386|Bacillus 91061|Bacilli C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes pdhD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyr_redox_2,Pyr_redox_dim k141_24271_1 754436.JCM19237_5912 5.35e-123 370.0 COG3868@1|root,COG3868@2|Bacteria,1MXYK@1224|Proteobacteria,1RMK1@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Glycoside-hydrolase family GH114 pelA - - ko:K21006 ko02025,map02025 - - - ko00000,ko00001 - - - Glyco_hydro_114 k141_24271_3 1122221.JHVI01000010_gene2565 3.62e-22 111.0 28KNN@1|root,2ZA6V@2|Bacteria,1WJGS@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus - - - - - - - - - - - - - - - k141_33854_1 1294265.JCM21738_1173 2.75e-120 347.0 COG1028@1|root,COG1028@2|Bacteria,1TR1J@1239|Firmicutes,4HAQ2@91061|Bacilli,1ZBZF@1386|Bacillus 91061|Bacilli IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - - - - - - - - - - adh_short_C2 k141_13799_1 218284.CCDN010000002_gene2853 1.69e-09 55.8 COG0789@1|root,COG0789@2|Bacteria,1V8QP@1239|Firmicutes,4HIWK@91061|Bacilli,1ZHGS@1386|Bacillus 91061|Bacilli K helix_turn_helix, mercury resistance - - - - - - - - - - - - MerR_1 k141_13799_2 1294265.JCM21738_824 2.51e-74 224.0 2AQ3P@1|root,31F8Y@2|Bacteria,1V8J9@1239|Firmicutes,4HJHH@91061|Bacilli,1ZGY3@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - Polyketide_cyc2 k141_31369_1 218284.CCDN010000001_gene92 6.76e-160 452.0 COG0275@1|root,COG0275@2|Bacteria,1TNZV@1239|Firmicutes,4H9U2@91061|Bacilli,1ZCHN@1386|Bacillus 91061|Bacilli J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA rsmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 ko:K03438 - - - - ko00000,ko01000,ko03009 - - - Methyltransf_5 k141_27730_1 218284.CCDN010000001_gene1795 2.12e-174 494.0 COG0174@1|root,COG0174@2|Bacteria,1TNZA@1239|Firmicutes,4HACE@91061|Bacilli,1ZBIQ@1386|Bacillus 91061|Bacilli E glutamine synthetase glnA GO:0003674,GO:0005488,GO:0005515,GO:0006082,GO:0006355,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0006808,GO:0007154,GO:0007584,GO:0008134,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009605,GO:0009719,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016053,GO:0016597,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043392,GO:0043436,GO:0043562,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0045892,GO:0045934,GO:0046394,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051098,GO:0051100,GO:0051101,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0061984,GO:0065007,GO:0065009,GO:0070406,GO:0070887,GO:0071310,GO:0071417,GO:0071495,GO:0071496,GO:0071704,GO:0080090,GO:0090293,GO:0090295,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901698,GO:1901699,GO:1902679,GO:1903506,GO:1903507,GO:1904796,GO:1904797,GO:2000112,GO:2000113,GO:2000677,GO:2000678,GO:2001141 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C,Gln-synt_N k141_14743_1 218284.CCDN010000001_gene1049 1.02e-110 332.0 COG0697@1|root,COG0697@2|Bacteria,1TP7K@1239|Firmicutes,4HBWN@91061|Bacilli,1ZB54@1386|Bacillus 91061|Bacilli EG Stage V sporulation protein AF spoVAF - - ko:K06408 - - - - ko00000 - - - GerA k141_18486_1 1379270.AUXF01000005_gene656 6.18e-87 278.0 COG0465@1|root,COG0465@2|Bacteria,1ZSRI@142182|Gemmatimonadetes 142182|Gemmatimonadetes O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins ftsH - - ko:K03798 - M00742 - - ko00000,ko00002,ko01000,ko01002,ko03110 - - - AAA,Peptidase_M41 k141_27745_2 502025.Hoch_4484 7.03e-48 164.0 COG5424@1|root,COG5424@2|Bacteria,1Q9R2@1224|Proteobacteria,434J3@68525|delta/epsilon subdivisions,2X8WX@28221|Deltaproteobacteria,2Z0SN@29|Myxococcales 28221|Deltaproteobacteria H Iron-containing redox enzyme - - - - - - - - - - - - Haem_oxygenas_2 k141_26958_1 1442599.JAAN01000043_gene480 4.84e-112 342.0 COG3661@1|root,COG3661@2|Bacteria,1MXKA@1224|Proteobacteria,1RP0V@1236|Gammaproteobacteria,1X5RV@135614|Xanthomonadales 135614|Xanthomonadales G Belongs to the glycosyl hydrolase 67 family aguA - 3.2.1.139 ko:K01235 - - - - ko00000,ko01000 - - - Glyco_hydro_67C,Glyco_hydro_67M,Glyco_hydro_67N k141_24298_1 702450.CUW_0190 3.18e-16 77.0 COG0355@1|root,COG0355@2|Bacteria 2|Bacteria C proton-transporting ATP synthase activity, rotational mechanism atpC GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - iJN746.PP_5412,iSbBS512_1146.SbBS512_E4190 ATP-synt_DE,ATP-synt_DE_N k141_24298_2 1042375.AFPL01000043_gene1409 7.92e-07 49.7 COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,1RN6U@1236|Gammaproteobacteria,465I5@72275|Alteromonadaceae 1236|Gammaproteobacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits atpD GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - e_coli_core.b3732,iAF1260.b3732,iAPECO1_1312.APECO1_2729,iB21_1397.B21_03560,iBWG_1329.BWG_3423,iE2348C_1286.E2348C_4042,iEC042_1314.EC042_4119,iEC55989_1330.EC55989_4207,iECABU_c1320.ECABU_c42160,iECBD_1354.ECBD_4300,iECB_1328.ECB_03616,iECDH10B_1368.ECDH10B_3919,iECDH1ME8569_1439.ECDH1ME8569_3620,iECD_1391.ECD_03616,iECED1_1282.ECED1_4422,iECH74115_1262.ECH74115_5168,iECIAI1_1343.ECIAI1_3916,iECIAI39_1322.ECIAI39_4336,iECNA114_1301.ECNA114_3881,iECO103_1326.ECO103_4426,iECO111_1330.ECO111_4566,iECO26_1355.ECO26_4846,iECOK1_1307.ECOK1_4181,iECP_1309.ECP_3931,iECS88_1305.ECS88_4154,iECSE_1348.ECSE_4022,iECSF_1327.ECSF_3580,iECSP_1301.ECSP_4782,iECUMN_1333.ECUMN_4262,iECW_1372.ECW_m4035,iECs_1301.ECs4674,iEKO11_1354.EKO11_4613,iETEC_1333.ETEC_4023,iEcDH1_1363.EcDH1_4235,iEcE24377_1341.EcE24377A_4247,iEcSMS35_1347.EcSMS35_4100,iEcolC_1368.EcolC_4262,iG2583_1286.G2583_4528,iJO1366.b3732,iJR904.b3732,iLF82_1304.LF82_0194,iNRG857_1313.NRG857_18585,iPC815.YPO4121,iSFV_1184.SFV_3758,iSF_1195.SF3812,iSFxv_1172.SFxv_4154,iSSON_1240.SSON_3887,iS_1188.S3956,iSbBS512_1146.SbBS512_E4189,iUMN146_1321.UM146_18850,iUMNK88_1353.UMNK88_4544,iUTI89_1310.UTI89_C4285,iWFL_1372.ECW_m4035,iY75_1357.Y75_RS18410,iZ_1308.Z5230,ic_1306.c4658 ATP-synt_ab,ATP-synt_ab_N k141_11372_2 1294265.JCM21738_3491 3.49e-34 117.0 2C5CS@1|root,33A0C@2|Bacteria,1VKIZ@1239|Firmicutes,4HRCC@91061|Bacilli,1ZJ2K@1386|Bacillus 91061|Bacilli S NETI protein yebG - - - - - - - - - - - NETI k141_2885_1 1121877.JQKF01000009_gene542 1.07e-28 111.0 COG0092@1|root,COG0092@2|Bacteria,2GKF1@201174|Actinobacteria,4CMU9@84992|Acidimicrobiia 84992|Acidimicrobiia J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation rpsC - - ko:K02982 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KH_2,Ribosomal_S3_C k141_2885_2 985762.SAGN_08840 4.17e-34 121.0 COG0091@1|root,COG0091@2|Bacteria,1V6PU@1239|Firmicutes,4HIK2@91061|Bacilli,4GZ52@90964|Staphylococcaceae 91061|Bacilli J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome rplV GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02890 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L22 k141_2885_3 1131269.AQVV01000036_gene1504 2.14e-44 145.0 COG0185@1|root,COG0185@2|Bacteria 2|Bacteria J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA rpsS GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02965 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S19 k141_6546_1 221109.22778520 6.3e-12 73.2 COG0584@1|root,COG0584@2|Bacteria,1UGF1@1239|Firmicutes,4H9QE@91061|Bacilli,23M1R@182709|Oceanobacillus 91061|Bacilli C Glycerophosphoryl diester phosphodiesterase family glpQ - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - GDPD k141_14757_1 1279017.AQYJ01000026_gene331 1.79e-153 434.0 COG1043@1|root,COG1043@2|Bacteria,1MUHQ@1224|Proteobacteria,1RPHB@1236|Gammaproteobacteria,464XE@72275|Alteromonadaceae 1236|Gammaproteobacteria M Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxA GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0008654,GO:0008780,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.129 ko:K00677 ko00540,ko01100,ko01503,map00540,map01100,map01503 M00060 R04567 RC00039,RC00055 ko00000,ko00001,ko00002,ko01000,ko01005 - - iPC815.YPO1056 Acetyltransf_11,Hexapep k141_14757_2 1042377.AFPJ01000037_gene2897 8.26e-94 274.0 COG0764@1|root,COG0764@2|Bacteria,1RH2T@1224|Proteobacteria,1S63E@1236|Gammaproteobacteria,466WK@72275|Alteromonadaceae 1236|Gammaproteobacteria I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs fabZ GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0008693,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019171,GO:0019752,GO:0032787,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0047451,GO:0071704,GO:0072330,GO:1901576 4.2.1.59 ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121 RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004 - - iJN746.PP_1602 FabA k141_10208_1 1294265.JCM21738_4077 1.1e-132 396.0 COG1948@1|root,COG4886@1|root,COG4880@2|Bacteria,COG4886@2|Bacteria,1TQK0@1239|Firmicutes,4H9YF@91061|Bacilli,1ZDVB@1386|Bacillus 91061|Bacilli L Beta propeller domain - - - - - - - - - - - - Beta_propel,Big_5,Cu_amine_oxidN1 k141_19630_2 218284.CCDN010000001_gene771 1.75e-37 127.0 2E5RP@1|root,330GA@2|Bacteria,1VI20@1239|Firmicutes,4HPUF@91061|Bacilli,1ZIUK@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2624) yqfT - - - - - - - - - - - DUF2624 k141_19630_3 218284.CCDN010000001_gene773 0.000256 42.7 COG1121@1|root,COG1121@2|Bacteria,1TQ68@1239|Firmicutes,4HAZI@91061|Bacilli,1ZBS5@1386|Bacillus 91061|Bacilli P 'COG1121 ABC-type Mn Zn transport systems, ATPase component' zurA - - ko:K02074,ko:K09817 ko02010,map02010 M00242,M00244 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 - - ABC_tran k141_35072_1 1116375.VEJY3_11125 1.39e-246 690.0 COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,1RNM8@1236|Gammaproteobacteria,1XTNT@135623|Vibrionales 135623|Vibrionales C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family fadH - 1.3.1.34 ko:K00219 - - - - ko00000,ko01000 - - - Oxidored_FMN,Pyr_redox_2 k141_35072_2 1116375.VEJY3_11120 1.01e-121 348.0 COG0778@1|root,COG0778@2|Bacteria,1PKUV@1224|Proteobacteria,1RNQG@1236|Gammaproteobacteria,1XU4Q@135623|Vibrionales 135623|Vibrionales C COG0778 Nitroreductase ydjA - - - - - - - - - - - Nitroreductase k141_35072_3 1116375.VEJY3_11115 0.0 1229.0 COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,1RN4X@1236|Gammaproteobacteria,1XUYY@135623|Vibrionales 135623|Vibrionales L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topB GO:0003674,GO:0003824,GO:0003916,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.2 ko:K03169 - - - - ko00000,ko01000,ko03032 - - - Topoisom_bac,Toprim k141_35072_4 1280001.BAOA01000008_gene4075 1.92e-36 123.0 2EFUY@1|root,339M4@2|Bacteria,1NGKE@1224|Proteobacteria,1SH9B@1236|Gammaproteobacteria,1XZ59@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_35072_5 1116375.VEJY3_11110 1.64e-141 402.0 COG1028@1|root,COG1028@2|Bacteria,1RHYX@1224|Proteobacteria,1S0GN@1236|Gammaproteobacteria,1XUNU@135623|Vibrionales 135623|Vibrionales IQ Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short k141_35072_6 1116375.VEJY3_11105 3.13e-200 556.0 COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,1RPVZ@1236|Gammaproteobacteria,1XUDB@135623|Vibrionales 135623|Vibrionales BQ COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein - - - - - - - - - - - - Hist_deacetyl k141_17179_1 666686.B1NLA3E_20375 2.53e-112 326.0 COG0479@1|root,COG0479@2|Bacteria,1TP17@1239|Firmicutes,4HAG7@91061|Bacilli,1ZMKN@1386|Bacillus 91061|Bacilli C 2Fe-2S iron-sulfur cluster binding domain - - 1.3.5.1,1.3.5.4 ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - Fer2_3,Fer4_8 k141_27746_1 626887.J057_13441 1.38e-121 367.0 COG3256@1|root,COG3256@2|Bacteria,1MVT1@1224|Proteobacteria,1RQ01@1236|Gammaproteobacteria,464BD@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG3256 Nitric oxide reductase large subunit norB - 1.7.2.5 ko:K04561 ko00910,ko01120,map00910,map01120 M00529 R00294 RC02794 ko00000,ko00001,ko00002,ko01000 3.D.4.10 - - COX1 k141_36113_1 674977.VMC_02050 8.33e-176 505.0 COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,1RMPG@1236|Gammaproteobacteria,1XU5H@135623|Vibrionales 135623|Vibrionales L DNA helicase recQ - 3.6.4.12 ko:K03654 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind k141_709_1 1172180.KB911785_gene415 2.63e-15 82.0 28UBU@1|root,2ZGH7@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k141_8963_1 1211114.ALIP01000130_gene2194 6.17e-60 199.0 COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,1RMCY@1236|Gammaproteobacteria,1X3CZ@135614|Xanthomonadales 135614|Xanthomonadales U Involved in the TonB-independent uptake of proteins tolB - - ko:K03641 - - - - ko00000,ko02000 2.C.1.2 - - PD40,TolB_N k141_6547_1 1348663.KCH_40900 3.32e-36 132.0 COG1999@1|root,COG1999@2|Bacteria,2GKF0@201174|Actinobacteria,2M0PT@2063|Kitasatospora 201174|Actinobacteria S SCO1/SenC - - - ko:K07152 - - - - ko00000,ko03029 - - - SCO1-SenC k141_18511_1 218284.CCDN010000002_gene2931 6.13e-137 394.0 COG1194@1|root,COG1194@2|Bacteria,1TPUT@1239|Firmicutes,4H9UM@91061|Bacilli,1ZD5Y@1386|Bacillus 91061|Bacilli L A G-specific mutY - - ko:K03575 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD,NUDIX_4 k141_33877_1 1042377.AFPJ01000014_gene1647 1.95e-181 513.0 COG0795@1|root,COG0795@2|Bacteria,1MVW3@1224|Proteobacteria,1RM8H@1236|Gammaproteobacteria,465SX@72275|Alteromonadaceae 1236|Gammaproteobacteria S permease lptG - - ko:K11720 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko02000 1.B.42.1 - - YjgP_YjgQ k141_33877_2 1453501.JELR01000001_gene2945 7.43e-190 536.0 COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,1RMN5@1236|Gammaproteobacteria,465H9@72275|Alteromonadaceae 1236|Gammaproteobacteria S permeases lptF - - ko:K07091 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko02000 1.B.42.1 - - YjgP_YjgQ k141_10209_1 1123318.KB904630_gene1755 0.000174 50.4 COG2132@1|root,COG2132@2|Bacteria,1TQSU@1239|Firmicutes,4HDD6@91061|Bacilli 91061|Bacilli Q Multicopper mco - - - - - - - - - - - Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3 k141_1670_1 218284.CCDN010000001_gene44 2.14e-147 420.0 COG0223@1|root,COG0223@2|Bacteria,1TQ32@1239|Firmicutes,4HART@91061|Bacilli,1ZBSP@1386|Bacillus 91061|Bacilli J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus fmt GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 ko:K00604 ko00670,ko00970,map00670,map00970 - R03940 RC00026,RC00165 ko00000,ko00001,ko01000 - - iSB619.SA_RS06010 Formyl_trans_C,Formyl_trans_N k141_5418_1 1042377.AFPJ01000045_gene2579 8.83e-95 304.0 COG4223@1|root,COG4223@2|Bacteria,1N10X@1224|Proteobacteria,1RYCQ@1236|Gammaproteobacteria,46D2D@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF1631) - - - - - - - - - - - - DUF1631 k141_5418_2 669262.COK_2094 5.64e-31 114.0 COG3023@1|root,COG3023@2|Bacteria,1RDHU@1224|Proteobacteria,1S3PG@1236|Gammaproteobacteria,1Y8II@135625|Pasteurellales 135625|Pasteurellales V Protein involved in N-acetylmuramoyl-L-alanine amidase activity and peptidoglycan catabolic process ampD GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043170,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 3.5.1.28 ko:K03806 - - - - ko00000,ko01000,ko01011 - - - Amidase_2 k141_20721_1 1123237.Salmuc_01503 4.82e-69 211.0 COG0250@1|root,COG0250@2|Bacteria,1MU14@1224|Proteobacteria,2TRID@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Participates in transcription elongation, termination and antitermination nusG GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - ko:K02601 - - - - ko00000,ko03009,ko03021 - - - KOW,NusG k141_20721_2 388399.SSE37_15131 3.56e-43 143.0 COG0080@1|root,COG0080@2|Bacteria,1RA2M@1224|Proteobacteria,2U760@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors rplK GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02867 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L11,Ribosomal_L11_N k141_13823_1 1116375.VEJY3_19611 4.41e-140 404.0 COG0738@1|root,COG0738@2|Bacteria,1QUEB@1224|Proteobacteria,1T1VW@1236|Gammaproteobacteria,1XT1X@135623|Vibrionales 135623|Vibrionales G of the major facilitator superfamily - - - - - - - - - - - - MFS_1,Sugar_tr k141_13823_2 1280001.BAOA01000072_gene2766 1.04e-77 232.0 2E4R1@1|root,32ZJK@2|Bacteria,1N8FZ@1224|Proteobacteria,1SAJ2@1236|Gammaproteobacteria,1XXUY@135623|Vibrionales 135623|Vibrionales S Nitrous oxide-stimulated promoter - - - - - - - - - - - - YgbA_NO k141_36114_1 697282.Mettu_3086 7.62e-14 71.2 COG0189@1|root,COG0189@2|Bacteria,1MX5X@1224|Proteobacteria,1RNXP@1236|Gammaproteobacteria,1XED7@135618|Methylococcales 135618|Methylococcales HJ PFAM ATP-grasp fold - - - - - - - - - - - - RLAN,RimK k141_24301_1 218284.CCDN010000006_gene3576 1.37e-39 145.0 COG0076@1|root,COG0076@2|Bacteria,1TSK0@1239|Firmicutes,4HC8W@91061|Bacilli,1ZQZN@1386|Bacillus 91061|Bacilli E Pyridoxal-dependent decarboxylase conserved domain sidD - 4.1.1.86 ko:K13745 ko00260,ko01120,map00260,map01120 - R07650 RC00299 ko00000,ko00001,ko01000 - - - Pyridoxal_deC k141_24301_2 1121938.AUDY01000008_gene926 1.73e-20 90.5 COG0160@1|root,COG0160@2|Bacteria,1TRUG@1239|Firmicutes,4HBUU@91061|Bacilli,3NEDR@45667|Halobacillus 91061|Bacilli E Aminotransferase class-III - - 2.6.1.76 ko:K00836 ko00260,ko01100,ko01120,ko01210,ko01230,map00260,map01100,map01120,map01210,map01230 M00033 R06977 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 k141_33878_1 398578.Daci_0272 2.92e-59 201.0 COG3182@1|root,COG3182@2|Bacteria,1MVET@1224|Proteobacteria,2VMKJ@28216|Betaproteobacteria,4AD7B@80864|Comamonadaceae 28216|Betaproteobacteria S PFAM PepSY-associated TM helix domain protein - - - - - - - - - - - - PepSY,PepSY_TM k141_17180_1 690585.JNNU01000007_gene1535 7.07e-36 129.0 29CEM@1|root,2ZZD2@2|Bacteria,1RB3W@1224|Proteobacteria,2U9X1@28211|Alphaproteobacteria,4BKZP@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_19632_1 42565.FP66_13945 9.21e-80 243.0 28ICJ@1|root,2Z8EW@2|Bacteria,1R4VQ@1224|Proteobacteria,1RRVS@1236|Gammaproteobacteria,1XP8I@135619|Oceanospirillales 135619|Oceanospirillales S Nucleoside-specific channel-forming protein, Tsx - - - - - - - - - - - - Channel_Tsx k141_5419_1 218284.CCDN010000001_gene1029 7.99e-112 323.0 COG2057@1|root,COG2057@2|Bacteria,1TNY5@1239|Firmicutes,4HBFR@91061|Bacilli,1ZB4Q@1386|Bacillus 91061|Bacilli I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit scoB - 2.8.3.5 ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 - R00410 RC00014 ko00000,ko00001,ko01000 - - - CoA_trans k141_1671_2 1196031.ALEG01000006_gene481 1.47e-24 96.7 2A3MM@1|root,30S4Y@2|Bacteria,1U28E@1239|Firmicutes,4IBSR@91061|Bacilli,1ZHG7@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_13824_1 1403313.AXBR01000018_gene3482 4.45e-60 209.0 COG1404@1|root,COG1404@2|Bacteria,1TPH1@1239|Firmicutes,4HBQH@91061|Bacilli,1ZBS0@1386|Bacillus 91061|Bacilli O Belongs to the peptidase S8 family prtS - 3.4.21.110,3.4.21.96 ko:K01361,ko:K08652 - - - - ko00000,ko01000,ko01002,ko03110 - - - FIVAR,Gram_pos_anchor,Inhibitor_I9,PA,Peptidase_S8,SLH,YSIRK_signal,fn3_5 k141_24302_2 218284.CCDN010000002_gene2194 1.74e-15 73.6 COG5012@1|root,COG5012@2|Bacteria,1V5DK@1239|Firmicutes,4HJ9Z@91061|Bacilli,1ZFGI@1386|Bacillus 91061|Bacilli S B12 binding domain - - - - - - - - - - - - B12-binding,B12-binding_2 k141_36211_3 1042377.AFPJ01000008_gene2032 5.64e-43 140.0 COG2835@1|root,COG2835@2|Bacteria 2|Bacteria EG tetraacyldisaccharide 4'-kinase activity - - - ko:K09791 - - - - ko00000 - - - Methyltransf_11,Methyltransf_25,Trm112p k141_36211_4 1042377.AFPJ01000008_gene2031 3.96e-252 693.0 COG0620@1|root,COG0620@2|Bacteria,1MUI9@1224|Proteobacteria,1RMBA@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation metE - 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_2698 Meth_synt_2 k141_36211_6 1042377.AFPJ01000008_gene2029 1.24e-174 494.0 COG0524@1|root,COG0524@2|Bacteria,1MUUC@1224|Proteobacteria,1RMN2@1236|Gammaproteobacteria,464Y8@72275|Alteromonadaceae 1236|Gammaproteobacteria G pfkB family carbohydrate kinase gsk GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008906,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237 2.7.1.15,2.7.1.4,2.7.1.73 ko:K00847,ko:K00852,ko:K00892 ko00030,ko00051,ko00230,ko00500,ko00520,ko01100,map00030,map00051,map00230,map00500,map00520,map01100 - R00760,R00867,R01051,R01131,R01228,R02750,R03920 RC00002,RC00017 ko00000,ko00001,ko01000 - - iSDY_1059.SDY_0442 PfkB k141_36211_7 1042377.AFPJ01000008_gene2028 0.0 1409.0 COG4774@1|root,COG4774@2|Bacteria 2|Bacteria P siderophore transport - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_36211_8 1042377.AFPJ01000008_gene2027 1.56e-310 848.0 COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,1RMW8@1236|Gammaproteobacteria,464HR@72275|Alteromonadaceae 1236|Gammaproteobacteria H May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine ahcY GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 ko:K01251 ko00270,ko01100,map00270,map01100 M00035 R00192,R04936 RC00056,RC00069,RC01161,RC01243 ko00000,ko00001,ko00002,ko01000,ko01009,ko04147 - - iYL1228.KPN_02462 AdoHcyase,AdoHcyase_NAD k141_36211_9 1042377.AFPJ01000008_gene2026 4.24e-267 735.0 COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,1RNV6@1236|Gammaproteobacteria,4642H@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme metK GO:0000096,GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004478,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006556,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009069,GO:0009108,GO:0009116,GO:0009119,GO:0009987,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0019752,GO:0030554,GO:0030955,GO:0031420,GO:0032553,GO:0032555,GO:0032559,GO:0033353,GO:0034641,GO:0035639,GO:0036094,GO:0042278,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0046872,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901576,GO:1901605,GO:1901657 2.5.1.6 ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 M00034,M00035,M00368,M00609 R00177,R04771 RC00021,RC01211 ko00000,ko00001,ko00002,ko01000 - - iYL1228.KPN_03375 S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N k141_36211_10 1042377.AFPJ01000008_gene2025 1.93e-213 605.0 COG0591@1|root,COG0591@2|Bacteria,1MUBI@1224|Proteobacteria,1RMXU@1236|Gammaproteobacteria,464J5@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - ko:K11928 - - - - ko00000,ko02000 2.A.21.2 - - SSF k141_36211_11 1042377.AFPJ01000008_gene2024 1.05e-258 711.0 COG4638@1|root,COG4638@2|Bacteria,1MXXI@1224|Proteobacteria,1RRNX@1236|Gammaproteobacteria,46DI3@72275|Alteromonadaceae 1236|Gammaproteobacteria P Rieske [2Fe-2S] domain - - - - - - - - - - - - Rieske k141_36211_12 1042377.AFPJ01000008_gene2023 3.54e-239 660.0 COG1804@1|root,COG1804@2|Bacteria,1MW1H@1224|Proteobacteria,1RN9B@1236|Gammaproteobacteria,46AB9@72275|Alteromonadaceae 1236|Gammaproteobacteria C CoA-transferase family III - - 2.8.3.16 ko:K07749 - - - - ko00000,ko01000 - - - CoA_transf_3 k141_36211_13 1042377.AFPJ01000008_gene2022 5.21e-222 618.0 COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,1RNB5@1236|Gammaproteobacteria,469JA@72275|Alteromonadaceae 1236|Gammaproteobacteria C CoA-transferase family III - - - - - - - - - - - - CoA_transf_3 k141_20825_1 649747.HMPREF0083_03730 3.5e-69 223.0 COG2031@1|root,COG2031@2|Bacteria,1TPCQ@1239|Firmicutes,4HAQF@91061|Bacilli,26U73@186822|Paenibacillaceae 91061|Bacilli I Short chain fatty acid transporter - - - ko:K02106 ko02020,map02020 - - - ko00000,ko00001 2.A.73.1 - - SCFA_trans k141_14004_1 1196031.ALEG01000063_gene3448 2.97e-157 444.0 COG1101@1|root,COG1101@2|Bacteria,1TPAN@1239|Firmicutes,4HCHC@91061|Bacilli,1ZCBE@1386|Bacillus 91061|Bacilli S transport system, ATPase component - - - ko:K05833 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_tran k141_1777_1 218284.CCDN010000002_gene2747 4.25e-101 304.0 COG0860@1|root,COG5632@1|root,COG0860@2|Bacteria,COG5632@2|Bacteria,1UYW5@1239|Firmicutes,4HF0Y@91061|Bacilli,1ZGSJ@1386|Bacillus 91061|Bacilli M N-acetylmuramoyl-L-alanine amidase - - - - - - - - - - - - - k141_10366_2 1196324.A374_15629 4.21e-64 207.0 COG4974@1|root,COG4974@2|Bacteria,1TRZV@1239|Firmicutes,4HCBD@91061|Bacilli 91061|Bacilli L Phage integrase family - - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_int_SAM_4,Phage_int_SAM_5,Phage_integrase k141_9105_1 218284.CCDN010000002_gene2042 2.16e-158 450.0 COG1131@1|root,COG1131@2|Bacteria,1TPQW@1239|Firmicutes,4HA3P@91061|Bacilli,1ZCNQ@1386|Bacillus 91061|Bacilli V ABC transporter, ATP-binding protein potA5 - - ko:K01990,ko:K16921 ko02010,map02010 M00254,M00584 - - ko00000,ko00001,ko00002,ko02000 3.A.1 - - ABC_tran k141_9105_2 218284.CCDN010000002_gene2041 2.58e-13 69.3 COG1277@1|root,COG1277@2|Bacteria,1TRJ8@1239|Firmicutes,4HA9I@91061|Bacilli,1ZCXM@1386|Bacillus 91061|Bacilli S ABC-type transport system involved in multi-copper enzyme maturation permease component - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - - k141_18689_2 1234664.AMRO01000076_gene2461 0.000817 39.3 2DKK7@1|root,309SD@2|Bacteria,1U5KR@1239|Firmicutes,4IFBQ@91061|Bacilli,1WH2T@129337|Geobacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_35275_2 1453501.JELR01000001_gene1872 6.32e-40 134.0 2CHAX@1|root,32ZC9@2|Bacteria,1N6X2@1224|Proteobacteria,1SCXD@1236|Gammaproteobacteria,468RC@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF3301) - - - - - - - - - - - - DUF3301 k141_27886_1 218284.CCDN010000001_gene766 1.96e-101 303.0 COG0327@1|root,COG0327@2|Bacteria,1TQ27@1239|Firmicutes,4H9NY@91061|Bacilli,1ZAPV@1386|Bacillus 91061|Bacilli S Belongs to the GTP cyclohydrolase I type 2 NIF3 family yqfO GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - - - - - - - - - - NIF3 k141_27140_1 1273538.G159_12050 7.91e-29 108.0 COG3402@1|root,COG3402@2|Bacteria,1VFTS@1239|Firmicutes,4HGMB@91061|Bacilli,26F1X@186818|Planococcaceae 91061|Bacilli S Bacterial PH domain ydbS - - ko:K09167 - - - - ko00000 - - - bPH_2 k141_27140_2 218284.CCDN010000004_gene3041 1.05e-20 89.4 COG4294@1|root,COG4294@2|Bacteria,1TTCB@1239|Firmicutes,4H9PY@91061|Bacilli,1ZCJ7@1386|Bacillus 91061|Bacilli L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion uvsE - - ko:K13281 - - - - ko00000,ko01000 - - - UvdE k141_35276_1 553385.JEMF01000074_gene1348 2.67e-36 140.0 COG1100@1|root,COG1100@2|Bacteria,1MWZW@1224|Proteobacteria,1RPD6@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Z1 domain - - - - - - - - - - - - Z1 k141_7748_2 311402.Avi_0819 4.57e-30 118.0 COG0687@1|root,COG0687@2|Bacteria,1MUYW@1224|Proteobacteria,2TSUZ@28211|Alphaproteobacteria,4B8SJ@82115|Rhizobiaceae 28211|Alphaproteobacteria P Required for the activity of the bacterial periplasmic transport system of putrescine potF GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015846,GO:0015847,GO:0019808,GO:0019810,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043167,GO:0043169,GO:0044464,GO:0051179,GO:0051234,GO:0070405,GO:0071702,GO:0071705 - ko:K11073 ko02010,map02010 M00300 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.2 - - SBP_bac_8 k141_29184_1 1294265.JCM21738_1895 6.08e-125 361.0 COG0210@1|root,COG0210@2|Bacteria,1TPVG@1239|Firmicutes,4HBVF@91061|Bacilli,1ZN04@1386|Bacillus 91061|Bacilli L UvrD-like helicase C-terminal domain yjcD - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - CoiA,UvrD-helicase,UvrD_C k141_12790_1 1500257.JQNM01000001_gene3704 6.11e-39 146.0 COG4425@1|root,COG4425@2|Bacteria,1MXSU@1224|Proteobacteria,2TV9M@28211|Alphaproteobacteria,4BBSJ@82115|Rhizobiaceae 28211|Alphaproteobacteria S Alpha/beta-hydrolase family - - - - - - - - - - - - Abhydrolase_9,Abhydrolase_9_N k141_12790_2 1042377.AFPJ01000007_gene1894 2.57e-32 115.0 2ENKU@1|root,33G87@2|Bacteria,1NMH6@1224|Proteobacteria,1SGDI@1236|Gammaproteobacteria,468YW@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_34025_1 1042377.AFPJ01000032_gene2699 4.33e-155 461.0 COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,1RNHV@1236|Gammaproteobacteria,46410@72275|Alteromonadaceae 1236|Gammaproteobacteria M Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) mrcB GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008289,GO:0008360,GO:0008658,GO:0008955,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031406,GO:0031975,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042277,GO:0042546,GO:0042597,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071723,GO:0071840,GO:0071944,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 2.4.1.129,3.4.16.4 ko:K05365 ko00550,map00550 - R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 iECIAI39_1322.ECIAI39_0153,iSBO_1134.SBO_0138,iSbBS512_1146.SbBS512_E0140,iYL1228.KPN_00164 PBP1_TM,Transgly,Transpeptidase,UB2H k141_22075_1 218284.CCDN010000004_gene3078 4.24e-178 516.0 COG3973@1|root,COG3973@2|Bacteria,1TP39@1239|Firmicutes,4H9Y5@91061|Bacilli,1ZAWP@1386|Bacillus 91061|Bacilli L DNA helicase helD_2 - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_19,UvrD-helicase,UvrD_C,UvrD_C_2 k141_11554_1 1279017.AQYJ01000028_gene2333 3.14e-167 482.0 COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,1RN3V@1236|Gammaproteobacteria,463ZU@72275|Alteromonadaceae 1236|Gammaproteobacteria FP Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the stringent response , an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities gppA - 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 - R03409 RC00002 ko00000,ko00001,ko01000 - - - HD,Ppx-GppA k141_16153_1 1307436.PBF_10867 2.11e-128 379.0 COG0697@1|root,COG0697@2|Bacteria,1TSX6@1239|Firmicutes,4HCV4@91061|Bacilli,1ZCUJ@1386|Bacillus 91061|Bacilli EG Bacillus/Clostridium GerA spore germination protein - - - - - - - - - - - - GerA k141_20838_1 627192.SLG_34090 3.35e-16 80.1 COG3307@1|root,COG3307@2|Bacteria,1MV4S@1224|Proteobacteria,2TV8W@28211|Alphaproteobacteria 28211|Alphaproteobacteria M -O-antigen - - - - - - - - - - - - - k141_31414_2 1116375.VEJY3_23081 3.36e-50 159.0 2AWFJ@1|root,31NBT@2|Bacteria,1QK2U@1224|Proteobacteria,1TI5K@1236|Gammaproteobacteria,1XYFB@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_31414_3 223926.28809767 5.71e-205 568.0 COG3833@1|root,COG3833@2|Bacteria,1QA3Z@1224|Proteobacteria,1RQ00@1236|Gammaproteobacteria,1XSY0@135623|Vibrionales 135623|Vibrionales P maltose transport malG GO:0003674,GO:0003824,GO:0005215,GO:0005363,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015154,GO:0015157,GO:0015399,GO:0015405,GO:0015422,GO:0015423,GO:0015766,GO:0015768,GO:0015772,GO:0015774,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0033037,GO:0034219,GO:0042623,GO:0042626,GO:0042956,GO:0043211,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702 - ko:K10110 ko02010,map02010 M00194 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.1,3.A.1.1.22 - - BPD_transp_1 k141_31414_4 1116375.VEJY3_23091 0.0 985.0 COG1175@1|root,COG1175@2|Bacteria,1MXKR@1224|Proteobacteria,1RN6B@1236|Gammaproteobacteria,1XTA3@135623|Vibrionales 135623|Vibrionales P Maltose transport system permease protein MalF malF GO:0003674,GO:0003824,GO:0005215,GO:0005363,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015154,GO:0015157,GO:0015399,GO:0015405,GO:0015422,GO:0015423,GO:0015766,GO:0015768,GO:0015772,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0032991,GO:0034219,GO:0042623,GO:0042626,GO:0043190,GO:0043211,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990060,GO:1990351 - ko:K10109 ko02010,map02010 M00194 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.1,3.A.1.1.22 - - BPD_transp_1,MalF_P2 k141_31414_5 1116375.VEJY3_23096 3.86e-281 768.0 COG2182@1|root,COG2182@2|Bacteria,1N9AE@1224|Proteobacteria,1RN4E@1236|Gammaproteobacteria,1XSVR@135623|Vibrionales 135623|Vibrionales G COG2182 Maltose-binding periplasmic proteins domains malE - - ko:K10108 ko02010,ko02030,map02010,map02030 M00194 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.1,3.A.1.1.22 - - SBP_bac_8 k141_31414_6 1116375.VEJY3_23101 1.3e-264 725.0 COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,1RM9E@1236|Gammaproteobacteria,1XSE0@135623|Vibrionales 135623|Vibrionales P Belongs to the ABC transporter superfamily malK GO:0003674,GO:0003824,GO:0005215,GO:0005363,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015154,GO:0015157,GO:0015399,GO:0015405,GO:0015422,GO:0015423,GO:0015766,GO:0015768,GO:0015772,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034219,GO:0042623,GO:0042626,GO:0043211,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702 - ko:K10111 ko02010,map02010 M00194,M00200,M00204,M00207,M00491 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.1 - - ABC_tran,TOBE_2 k141_31414_7 223926.28809771 1.17e-292 804.0 COG2148@1|root,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,1RMMN@1236|Gammaproteobacteria,1XTWQ@135623|Vibrionales 135623|Vibrionales M COG2148 Sugar transferases involved in lipopolysaccharide synthesis - - - ko:K03606 ko05111,map05111 - - - ko00000,ko00001 - - - Bac_transf,CoA_binding_3 k141_31414_8 223926.28809772 5.14e-225 629.0 COG5338@1|root,COG5338@2|Bacteria,1R56M@1224|Proteobacteria,1S0PC@1236|Gammaproteobacteria,1XWEX@135623|Vibrionales 135623|Vibrionales S Putative beta-barrel porin 2 - - - ko:K20920 ko05111,map05111 - - - ko00000,ko00001,ko02000 1.B.66.3.1,1.B.66.3.2 - - BBP2_2 k141_31414_9 223926.28809773 1.27e-108 314.0 COG1596@1|root,COG1596@2|Bacteria,1MXYS@1224|Proteobacteria,1SC60@1236|Gammaproteobacteria,1Y2XB@135623|Vibrionales 135623|Vibrionales M COG1596 Periplasmic protein involved in polysaccharide export - - - ko:K20988 ko05111,map05111 - - - ko00000,ko00001,ko02000 1.B.18 - - Poly_export,SLBB k141_31414_10 1219076.N646_3121 0.0 1179.0 COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,1MVI9@1224|Proteobacteria,1RNB0@1236|Gammaproteobacteria,1XTE5@135623|Vibrionales 135623|Vibrionales D protein involved in exopolysaccharide biosynthesis - - - ko:K16554 ko05111,map05111 - - - ko00000,ko00001,ko02000 8.A.3.1 - - AAA_31,GNVR,Wzz k141_31414_11 674977.VMC_20630 2.71e-206 577.0 COG0438@1|root,COG0438@2|Bacteria,1NAE9@1224|Proteobacteria,1RYZG@1236|Gammaproteobacteria,1XTUW@135623|Vibrionales 135623|Vibrionales M Glycosyltransferase Family 4 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 k141_25833_1 1385513.N780_01040 4.76e-138 402.0 COG0591@1|root,COG0591@2|Bacteria,1U5X8@1239|Firmicutes,4HD7K@91061|Bacilli,2YBFX@289201|Pontibacillus 91061|Bacilli E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family putP_2 - - ko:K03307 - - - - ko00000 2.A.21 - - SSF k141_11555_1 1294265.JCM21738_911 1.86e-94 281.0 COG3620@1|root,COG3620@2|Bacteria,1V3XA@1239|Firmicutes,4HHRH@91061|Bacilli,1ZFDU@1386|Bacillus 91061|Bacilli K CBS domain - - - - - - - - - - - - CBS k141_3004_1 1232443.BAIA02000073_gene542 7.46e-09 62.0 COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,2480S@186801|Clostridia,2690V@186813|unclassified Clostridiales 186801|Clostridia M D-alanyl-D-alanine carboxypeptidase dacB_3 - 3.4.16.4 ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - CW_binding_1,PBP5_C,Peptidase_S11 k141_14022_1 218284.CCDN010000001_gene270 9.88e-85 270.0 COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,4H9SP@91061|Bacilli,1ZAPS@1386|Bacillus 91061|Bacilli P COG2217 Cation transport ATPase cadA - 3.6.3.3,3.6.3.5 ko:K01534 - - - - ko00000,ko01000 3.A.3.6 - - E1-E2_ATPase,HMA,Hydrolase k141_14022_2 1385511.N783_01435 2.58e-44 149.0 COG3708@1|root,COG3708@2|Bacteria,1V9EU@1239|Firmicutes,4HIM4@91061|Bacilli 91061|Bacilli K Integron-associated effector binding protein - - - - - - - - - - - - Cass2,GyrI-like k141_36225_1 218284.CCDN010000001_gene281 3.52e-102 296.0 COG1522@1|root,COG1522@2|Bacteria,1V88V@1239|Firmicutes,4IS29@91061|Bacilli,1ZS0P@1386|Bacillus 91061|Bacilli K helix_turn_helix ASNC type - - - - - - - - - - - - AsnC_trans_reg,HTH_24 k141_29210_1 1034347.CAHJ01000029_gene3540 4.3e-102 315.0 COG0556@1|root,COG0556@2|Bacteria,1TPKB@1239|Firmicutes,4HB81@91061|Bacilli,1ZC50@1386|Bacillus 91061|Bacilli L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage uvrB - - ko:K03702 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - Helicase_C,ResIII,UVR,UvrB k141_32686_1 1042377.AFPJ01000024_gene743 5.65e-170 489.0 COG2199@1|root,COG3706@2|Bacteria,1MWHH@1224|Proteobacteria,1RRU7@1236|Gammaproteobacteria,465TD@72275|Alteromonadaceae 1236|Gammaproteobacteria T 7TMR-DISM extracellular 2 - - - - - - - - - - - - 7TMR-DISMED2,7TMR-DISM_7TM,GGDEF k141_18719_1 218284.CCDN010000001_gene552 2.45e-13 68.6 COG1039@1|root,COG1039@2|Bacteria,1TQBE@1239|Firmicutes,4H9QR@91061|Bacilli,1ZBHW@1386|Bacillus 91061|Bacilli L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhC GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03471 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DUF3378,RNase_HII k141_18719_3 218284.CCDN010000001_gene554 5.37e-111 320.0 COG1286@1|root,COG1286@2|Bacteria,1V7U0@1239|Firmicutes,4HIUU@91061|Bacilli,1ZDGZ@1386|Bacillus 91061|Bacilli S membrane protein, required for colicin V production yshB - - - - - - - - - - - Colicin_V k141_24512_1 935836.JAEL01000021_gene1538 8.22e-85 268.0 COG2936@1|root,COG2936@2|Bacteria,1TT78@1239|Firmicutes,4HBA0@91061|Bacilli,1ZDSR@1386|Bacillus 91061|Bacilli S Xaa-Pro dipeptidyl-peptidase pepX - 3.4.14.11 ko:K01281 - - - - ko00000,ko01000,ko01002 - - - PepX_C,PepX_N,Peptidase_S15 k141_7777_1 1236973.JCM9157_2136 2.04e-110 337.0 COG1961@1|root,COG1961@2|Bacteria,1TPUG@1239|Firmicutes,4HB3H@91061|Bacilli,1ZBV3@1386|Bacillus 91061|Bacilli L Recombinase - GO:0000150,GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140097,GO:1901360 - ko:K06400 - - - - ko00000 - - - Recombinase,Resolvase,Zn_ribbon_recom k141_7777_3 1403313.AXBR01000002_gene4296 2.01e-46 156.0 2BZV8@1|root,30HHG@2|Bacteria,1V68P@1239|Firmicutes,4HHRU@91061|Bacilli,1ZHNM@1386|Bacillus 91061|Bacilli S Replication-relaxation - - - - - - - - - - - - Replic_Relax k141_5616_1 1116375.VEJY3_22046 2.25e-88 263.0 COG3619@1|root,COG3619@2|Bacteria,1RB5Q@1224|Proteobacteria,1S70A@1236|Gammaproteobacteria,1XU9T@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF1275) - - - - - - - - - - - - DUF1275 k141_5616_2 1116375.VEJY3_22051 2.86e-303 830.0 COG3314@1|root,COG3314@2|Bacteria,1NEAN@1224|Proteobacteria,1RPX6@1236|Gammaproteobacteria,1XTQR@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria - - - - - - - - - - - - Gate k141_5616_3 1116375.VEJY3_22056 1.29e-308 857.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XUI8@135623|Vibrionales 135623|Vibrionales NT methyl-accepting chemotaxis protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal,dCache_1 k141_1795_1 218284.CCDN010000001_gene557 7.81e-82 243.0 COG3766@1|root,COG3766@2|Bacteria,1V6MT@1239|Firmicutes,4HH4E@91061|Bacilli,1ZG9Y@1386|Bacillus 91061|Bacilli S membrane yshE - - ko:K08989 - - - - ko00000 - - - DUF350 k141_9128_1 218284.CCDN010000001_gene46 7.32e-175 509.0 COG1198@1|root,COG1198@2|Bacteria,1TNYB@1239|Firmicutes,4H9WW@91061|Bacilli,1ZCBY@1386|Bacillus 91061|Bacilli L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA priA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - ko:K04066 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,ResIII k141_9128_2 218284.CCDN010000001_gene45 1.81e-102 297.0 COG0242@1|root,COG0242@2|Bacteria,1V70B@1239|Firmicutes,4HHMA@91061|Bacilli,1ZGES@1386|Bacillus 91061|Bacilli J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions def GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008463,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 ko:K01462 - - - - ko00000,ko01000 - - - Pep_deformylase k141_842_1 1117379.BABA_09861 2.69e-71 244.0 COG2909@1|root,COG3629@1|root,COG2909@2|Bacteria,COG3629@2|Bacteria,1UWHI@1239|Firmicutes,4HADH@91061|Bacilli,1ZE89@1386|Bacillus 91061|Bacilli KT COG2909 ATP-dependent transcriptional regulator - - - ko:K03556 - - - - ko00000,ko03000 - - - AAA_16,BTAD,TPR_12,TPR_8 k141_7778_1 1236973.JCM9157_3363 2.64e-31 122.0 28I0M@1|root,2Z85B@2|Bacteria,1TTBC@1239|Firmicutes,4HENN@91061|Bacilli,1ZEXZ@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3231) - - - - - - - - - - - - DUF3231 k141_29211_1 1279017.AQYJ01000028_gene2540 4.87e-102 317.0 COG0515@1|root,COG0631@1|root,COG0515@2|Bacteria,COG0631@2|Bacteria,1MV1P@1224|Proteobacteria,1RNQN@1236|Gammaproteobacteria,464NH@72275|Alteromonadaceae 1236|Gammaproteobacteria T Serine threonine protein ppkB - - - - - - - - - - - PP2C_2,Pkinase k141_6719_1 1042377.AFPJ01000028_gene2210 1.53e-91 296.0 COG0834@1|root,COG4623@1|root,COG0834@2|Bacteria,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,1RM8W@1236|Gammaproteobacteria,467JF@72275|Alteromonadaceae 1236|Gammaproteobacteria EMT Bacterial periplasmic substrate-binding proteins - GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - ko:K18691 - - - - ko00000,ko01000,ko01011 - - - SBP_bac_3,SLT k141_6719_2 1042377.AFPJ01000035_gene2620 3.39e-284 809.0 COG0834@1|root,COG4623@1|root,COG0834@2|Bacteria,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,1RM8W@1236|Gammaproteobacteria,467JF@72275|Alteromonadaceae 1236|Gammaproteobacteria EMT Bacterial periplasmic substrate-binding proteins - GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - ko:K18691 - - - - ko00000,ko01000,ko01011 - - - SBP_bac_3,SLT k141_6719_5 1042377.AFPJ01000035_gene2617 3.42e-118 343.0 COG4659@1|root,COG4659@2|Bacteria,1RDEP@1224|Proteobacteria,1RPAD@1236|Gammaproteobacteria,4672J@72275|Alteromonadaceae 1236|Gammaproteobacteria C Part of a membrane complex involved in electron transport rnfG - - ko:K03612 - - - - ko00000 - - - FMN_bind k141_6719_6 1279017.AQYJ01000022_gene2627 3.41e-208 580.0 COG4658@1|root,COG4658@2|Bacteria,1MVY6@1224|Proteobacteria,1RMEU@1236|Gammaproteobacteria,464JB@72275|Alteromonadaceae 1236|Gammaproteobacteria C Part of a membrane complex involved in electron transport rnfD GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0044464,GO:0055114,GO:0071944 - ko:K03614 - - - - ko00000 - - - NQR2_RnfD_RnfE k141_6719_7 1279017.AQYJ01000022_gene2628 3.65e-26 111.0 COG4656@1|root,COG4656@2|Bacteria,1QTUI@1224|Proteobacteria,1RMIM@1236|Gammaproteobacteria,4655V@72275|Alteromonadaceae 1236|Gammaproteobacteria C Part of a membrane complex involved in electron transport rnfC GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0055114 - ko:K03615 - - - - ko00000 - - - Complex1_51K,Fer4_10,Fer4_7,Fer4_8,RnfC_N,SLBB k141_11556_1 1279017.AQYJ01000023_gene3293 1.27e-226 654.0 COG3525@1|root,COG3525@2|Bacteria,1MVDE@1224|Proteobacteria,1RMNI@1236|Gammaproteobacteria,465K7@72275|Alteromonadaceae 1236|Gammaproteobacteria G Putative carbohydrate binding domain chb - 3.2.1.52 ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 M00079 R00022,R06004,R11316 RC00049 ko00000,ko00001,ko00002,ko01000,ko03110 - GH20 - CHB_HEX,CHB_HEX_C,Glyco_hydro_20,Glyco_hydro_20b k141_1796_1 471223.GWCH70_1320 7.6e-111 331.0 COG0161@1|root,COG0161@2|Bacteria,1TP9N@1239|Firmicutes,4HAA5@91061|Bacilli,1WF7X@129337|Geobacillus 91061|Bacilli H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - 2.6.1.113 ko:K12256 ko00330,ko01100,map00330,map01100 - R08714 RC00008,RC00062 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_3 k141_24513_1 218284.CCDN010000001_gene177 2.82e-127 371.0 COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,4H9SG@91061|Bacilli,1ZC15@1386|Bacillus 91061|Bacilli E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate hipO GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0050118,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.1.47 ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 M00525 R02733 RC00064,RC00300 ko00000,ko00001,ko00002,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 k141_24513_2 218284.CCDN010000001_gene168 1.12e-47 159.0 COG0668@1|root,COG0668@2|Bacteria,1TR9Z@1239|Firmicutes,4HCB8@91061|Bacilli,1ZCW4@1386|Bacillus 91061|Bacilli M Mechanosensitive ion channel ykuT GO:0003674,GO:0005215,GO:0006810,GO:0006950,GO:0006970,GO:0008150,GO:0008381,GO:0009628,GO:0009987,GO:0015267,GO:0022803,GO:0022836,GO:0022857,GO:0033554,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071214,GO:0071470,GO:0104004 - ko:K22044 - - - - ko00000,ko02000 1.A.23.3 - - MS_channel k141_7779_1 1280001.BAOA01000060_gene2324 1.02e-57 202.0 COG3096@1|root,COG3096@2|Bacteria,1MUWM@1224|Proteobacteria,1RPFF@1236|Gammaproteobacteria,1XUHB@135623|Vibrionales 135623|Vibrionales D Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division mukB GO:0007059,GO:0008150,GO:0009987 - ko:K03632 - - - - ko00000,ko03036 - - - MukB,MukB_hinge,SbcCD_C k141_23447_1 1218173.BALCAV_0202695 4.48e-12 71.2 28KI6@1|root,2ZA3G@2|Bacteria,1UYE9@1239|Firmicutes,4HB9Y@91061|Bacilli,1ZF3A@1386|Bacillus 91061|Bacilli S Spore germination B3/ GerAC like, C-terminal - - - - - - - - - - - - Spore_GerAC k141_29212_1 1347086.CCBA010000031_gene966 9.79e-10 55.5 2DGN4@1|root,2ZWMV@2|Bacteria,1W6QT@1239|Firmicutes,4I0RX@91061|Bacilli,1ZJJ1@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_32688_2 218284.CCDN010000001_gene1879 3.95e-44 145.0 COG1873@1|root,COG1873@2|Bacteria,1VEJW@1239|Firmicutes,4HPFQ@91061|Bacilli,1ZI6Z@1386|Bacillus 91061|Bacilli S YlmC YmxH family ymxH - - - - - - - - - - - PRC k141_14025_1 218284.CCDN010000001_gene1924 1.13e-47 156.0 2E35U@1|root,32Y5R@2|Bacteria,1VEH9@1239|Firmicutes,4HMCM@91061|Bacilli,1ZQS3@1386|Bacillus 91061|Bacilli N Putative flagellar flg - - - - - - - - - - - Flagellar_put k141_22096_3 1453501.JELR01000001_gene2218 6.19e-87 261.0 COG0546@1|root,COG0546@2|Bacteria,1RDA7@1224|Proteobacteria,1S3T3@1236|Gammaproteobacteria,4674R@72275|Alteromonadaceae 1236|Gammaproteobacteria S Hydrolase gph - 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 - R01334 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 k141_9129_1 218284.CCDN010000001_gene636 4.46e-111 320.0 COG3290@1|root,COG3290@2|Bacteria,1V8IS@1239|Firmicutes,4HQ4T@91061|Bacilli,1ZHUN@1386|Bacillus 91061|Bacilli T Sporulation initiation phospho-transferase B, C-terminal spo0B GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K06375 ko02020,ko02024,map02020,map02024 - - - ko00000,ko00001,ko01000 - - - SPOB_a,SPOB_ab k141_20839_1 1219065.VPR01S_01_02990 4.09e-110 335.0 COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,1RMYY@1236|Gammaproteobacteria,1XWB0@135623|Vibrionales 135623|Vibrionales M Mechanosensitive ion channel - - - - - - - - - - - - MS_channel,MscS_TM k141_16154_2 1042377.AFPJ01000021_gene2117 1.04e-58 199.0 COG2244@1|root,COG2244@2|Bacteria 2|Bacteria S polysaccharide biosynthetic process - - - - - - - - - - - - MatE,Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C k141_14897_1 997296.PB1_15489 2.78e-159 457.0 COG1559@1|root,COG1559@2|Bacteria,1TS48@1239|Firmicutes,4HAUV@91061|Bacilli,1ZC44@1386|Bacillus 91061|Bacilli S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation mltG - - ko:K07082 - - - - ko00000 - - - YceG k141_24514_1 218284.CCDN010000006_gene3594 6.11e-194 553.0 COG0843@1|root,COG0843@2|Bacteria,1TP2U@1239|Firmicutes,4HA4X@91061|Bacilli,1ZBD5@1386|Bacillus 91061|Bacilli C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B qoxB GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009486,GO:0009987,GO:0015002,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016310,GO:0016491,GO:0016679,GO:0016682,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0034220,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0098655,GO:0098660,GO:0098662,GO:1901135,GO:1901360,GO:1901564,GO:1902600 1.10.3.12 ko:K02827 ko00190,ko01100,map00190,map01100 M00416 R09492 RC00819 ko00000,ko00001,ko00002,ko01000 3.D.4.1 - - COX1 k141_23448_1 1219076.N646_1171 3.04e-159 450.0 COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,1RR68@1236|Gammaproteobacteria,1XSSR@135623|Vibrionales 135623|Vibrionales H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate moaA GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.22 ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09394 RC03420 ko00000,ko00001,ko01000 - - - Fer4_12,Mob_synth_C,Radical_SAM k141_1797_1 1279017.AQYJ01000027_gene1683 2.33e-105 334.0 COG5013@1|root,COG5013@2|Bacteria,1MW9S@1224|Proteobacteria,1RQ27@1236|Gammaproteobacteria,465D5@72275|Alteromonadaceae 1236|Gammaproteobacteria C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family narG GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009898,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0031235,GO:0032991,GO:0042126,GO:0043436,GO:0043546,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0097159,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098803,GO:1901363,GO:1902494,GO:1990204,GO:2001057 1.7.5.1 ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 M00529,M00530,M00804 R00798,R01106,R09497 RC02812 ko00000,ko00001,ko00002,ko01000 5.A.3.1 - iSBO_1134.SBO_1842,iUMN146_1321.UM146_09685 Molybdopterin,Molydop_binding,Nitr_red_alph_N k141_37448_1 1219076.N646_1002 2.25e-56 180.0 COG0807@1|root,COG0807@2|Bacteria,1MWZR@1224|Proteobacteria,1RMFX@1236|Gammaproteobacteria,1XU21@135623|Vibrionales 135623|Vibrionales F Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate ribA GO:0003674,GO:0003824,GO:0003933,GO:0003935,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019238,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.5.4.25 ko:K01497 ko00740,ko00790,ko01100,ko01110,ko02024,map00740,map00790,map01100,map01110,map02024 M00125 R00425 RC00293,RC02504 ko00000,ko00001,ko00002,ko01000 - - - GTP_cyclohydro2 k141_37448_2 223926.28806140 7.01e-130 371.0 COG1434@1|root,COG1434@2|Bacteria,1N4TG@1224|Proteobacteria,1RSJ5@1236|Gammaproteobacteria,1XWHV@135623|Vibrionales 135623|Vibrionales S DUF218 domain - - - - - - - - - - - - DUF218 k141_37448_3 1116375.VEJY3_05630 6.88e-159 449.0 COG0451@1|root,COG0451@2|Bacteria,1MWVJ@1224|Proteobacteria,1RNDT@1236|Gammaproteobacteria,1XTJV@135623|Vibrionales 135623|Vibrionales GM COG0451 Nucleoside-diphosphate-sugar epimerases - - - - - - - - - - - - Epimerase,NAD_binding_10,RmlD_sub_bind k141_12916_3 1385517.N800_07205 5.98e-22 87.0 COG3205@1|root,COG3205@2|Bacteria,1N85D@1224|Proteobacteria,1SCCN@1236|Gammaproteobacteria,1X84M@135614|Xanthomonadales 135614|Xanthomonadales S Predicted membrane protein (DUF2061) - - - - - - - - - - - - DUF2061 k141_23748_3 1121935.AQXX01000090_gene3837 2.2e-51 164.0 COG3324@1|root,COG3324@2|Bacteria,1N0AD@1224|Proteobacteria,1S8YM@1236|Gammaproteobacteria,1XKJ4@135619|Oceanospirillales 135619|Oceanospirillales S glyoxalase - - - ko:K06996 - - - - ko00000 - - - Glyoxalase k141_1043_1 218284.CCDN010000005_gene3206 2.19e-38 135.0 COG4565@1|root,COG4565@2|Bacteria,1V3PK@1239|Firmicutes,4HGXB@91061|Bacilli,1ZFRB@1386|Bacillus 91061|Bacilli T COG4565 Response regulator of citrate malate metabolism dcuR - - ko:K02475,ko:K11615 ko02020,map02020 M00490 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_11,Response_reg k141_1043_2 218284.CCDN010000005_gene3207 9.24e-68 218.0 COG3493@1|root,COG3493@2|Bacteria,1TR97@1239|Firmicutes,4HBS8@91061|Bacilli,1ZC12@1386|Bacillus 91061|Bacilli C COG3493 Na citrate symporter mleP - - - - - - - - - - - 2HCT k141_35480_2 1279017.AQYJ01000024_gene1183 2.95e-222 620.0 COG1680@1|root,COG1680@2|Bacteria,1MY01@1224|Proteobacteria,1RNUI@1236|Gammaproteobacteria,464GK@72275|Alteromonadaceae 1236|Gammaproteobacteria V COG1680 Beta-lactamase class C and other penicillin binding proteins ampC - 3.5.2.6 ko:K01467 ko01501,ko02020,map01501,map02020 M00628 R06363 RC01499 ko00000,ko00001,ko00002,ko01000 - - - Beta-lactamase k141_24720_1 218284.CCDN010000003_gene2998 2.11e-54 176.0 COG2318@1|root,COG2318@2|Bacteria,1VAGC@1239|Firmicutes,4HMA9@91061|Bacilli,1ZFRM@1386|Bacillus 91061|Bacilli S DinB superfamily - - - - - - - - - - - - DinB_2 k141_4400_2 1279017.AQYJ01000025_gene572 2.75e-70 226.0 COG3297@1|root,COG3297@2|Bacteria,1NVVW@1224|Proteobacteria,1S01F@1236|Gammaproteobacteria,4684Z@72275|Alteromonadaceae 1236|Gammaproteobacteria U GspL periplasmic domain gspL GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - ko:K02461 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - GspL_C,T2SSL k141_5759_1 218284.CCDN010000008_gene4202 1.29e-109 321.0 COG0491@1|root,COG0491@2|Bacteria,1TRED@1239|Firmicutes,4HAP2@91061|Bacilli,1ZAYX@1386|Bacillus 91061|Bacilli S COG0491 Zn-dependent hydrolases, including glyoxylases ytnP - - - - - - - - - - - Lactamase_B k141_5759_2 345219.Bcoa_2442 1.03e-33 119.0 COG5584@1|root,COG5584@2|Bacteria,1VEIQ@1239|Firmicutes,4HNS2@91061|Bacilli,1ZJ31@1386|Bacillus 91061|Bacilli S small secreted protein ytzB - - - - - - - - - - - PepSY k141_5759_3 218284.CCDN010000008_gene4204 1.59e-84 258.0 COG1363@1|root,COG1363@2|Bacteria,1TNZT@1239|Firmicutes,4H9SM@91061|Bacilli,1ZAXE@1386|Bacillus 91061|Bacilli G COG1363 Cellulase M and related proteins pepA - 3.4.11.7 ko:K01261,ko:K01269 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M42 k141_34212_1 1279017.AQYJ01000029_gene3802 1.68e-163 469.0 COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,1RMSE@1236|Gammaproteobacteria,464G9@72275|Alteromonadaceae 1236|Gammaproteobacteria EH COG0147 Anthranilate para-aminobenzoate synthases component I pabB GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.6.1.85 ko:K01665 ko00790,map00790 - R01716 RC00010,RC01418 ko00000,ko00001,ko01000 - - iEC042_1314.EC042_1977 Anth_synt_I_N,Chorismate_bind k141_22409_1 218284.CCDN010000001_gene25 6.86e-115 333.0 COG0571@1|root,COG0571@2|Bacteria,1TPGC@1239|Firmicutes,4HAWU@91061|Bacilli,1ZAPM@1386|Bacillus 91061|Bacilli J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism rnc GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 ko:K03685 ko03008,ko05205,map03008,map05205 - - - ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 - - - Ribonucleas_3_3,dsrm k141_28020_1 570967.JMLV01000011_gene3367 3.78e-87 265.0 COG1028@1|root,COG1028@2|Bacteria,1R413@1224|Proteobacteria,2TW0W@28211|Alphaproteobacteria,2JSIE@204441|Rhodospirillales 204441|Rhodospirillales IQ KR domain - - - - - - - - - - - - adh_short_C2 k141_3213_1 1123236.KB899376_gene1211 1.86e-95 297.0 COG0784@1|root,COG5002@1|root,COG0784@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,1SVEC@1236|Gammaproteobacteria,46D68@72275|Alteromonadaceae 1236|Gammaproteobacteria T response regulator - - 2.1.1.80,3.1.1.61 ko:K13924 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 - - - CheB_methylest,CheR,CheR_N,HATPase_c,HisKA,PAS_10,PAS_4,Response_reg k141_29393_2 218284.CCDN010000004_gene3118 2.55e-87 258.0 COG0394@1|root,COG0394@2|Bacteria,1U8S1@1239|Firmicutes,4IIQ8@91061|Bacilli,1ZNXR@1386|Bacillus 91061|Bacilli T Low molecular weight phosphatase family - - - - - - - - - - - - - k141_11772_1 1294265.JCM21738_5063 3.24e-28 101.0 2EESV@1|root,338KD@2|Bacteria,1VFET@1239|Firmicutes,4HP8V@91061|Bacilli,1ZIWM@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_11772_2 1294265.JCM21738_5062 2.38e-28 102.0 2A0JV@1|root,30NQ2@2|Bacteria,1TWUS@1239|Firmicutes,4HS9X@91061|Bacilli,1ZJXW@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3813) - - - - - - - - - - - - DUF3813 k141_11772_3 1294265.JCM21738_5061 3.26e-61 191.0 2AYP4@1|root,31QTN@2|Bacteria,1UW67@1239|Firmicutes,4IC2T@91061|Bacilli,1ZF0A@1386|Bacillus 91061|Bacilli S Intracellular proteinase inhibitor - - - - - - - - - - - - BsuPI,Gmad2 k141_20971_1 218284.CCDN010000001_gene132 5.98e-223 648.0 COG1038@1|root,COG1038@2|Bacteria,1UHP9@1239|Firmicutes,4IS56@91061|Bacilli,1ZC4R@1386|Bacillus 91061|Bacilli C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second pyc - 6.4.1.1 ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 M00173 R00344 RC00040,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,HMGL-like,PYC_OADA k141_12937_1 218284.CCDN010000006_gene3641 6.11e-56 178.0 COG0131@1|root,COG0131@2|Bacteria,1TRH7@1239|Firmicutes,4HCFG@91061|Bacilli,1ZBVJ@1386|Bacillus 91061|Bacilli E imidazoleglycerol-phosphate dehydratase hisB GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R03457 RC00932 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS14130 IGPD k141_12937_2 218284.CCDN010000006_gene3642 1.51e-67 217.0 COG0141@1|root,COG0141@2|Bacteria,1TPAW@1239|Firmicutes,4H9XK@91061|Bacilli,1ZCAX@1386|Bacillus 91061|Bacilli E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine hisD GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01158,R01163,R03012 RC00099,RC00242,RC00463 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU34910 Histidinol_dh k141_26035_1 218284.CCDN010000001_gene137 1.53e-157 451.0 COG1875@1|root,COG1875@2|Bacteria,1UHTD@1239|Firmicutes,4HA4V@91061|Bacilli,1ZDIF@1386|Bacillus 91061|Bacilli T ATPase related to phosphate starvation-inducible protein PhoH ylaK - - ko:K07175 - - - - ko00000 - - - PIN_4,PhoH k141_26035_2 218284.CCDN010000001_gene138 5.62e-97 289.0 2A3AP@1|root,30RSQ@2|Bacteria,1VA69@1239|Firmicutes,4HKTQ@91061|Bacilli,1ZFXZ@1386|Bacillus 91061|Bacilli S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) ylaJ - - - - - - - - - - - Spore_YhcN_YlaJ k141_22410_1 1303518.CCALI_00532 8.31e-19 85.5 COG0476@1|root,COG0607@1|root,COG1977@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,COG1977@2|Bacteria 2|Bacteria H Mo-molybdopterin cofactor metabolic process moeB GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006732,GO:0006777,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008146,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016782,GO:0018130,GO:0019344,GO:0019538,GO:0019637,GO:0019720,GO:0019752,GO:0020012,GO:0030312,GO:0030682,GO:0042783,GO:0043170,GO:0043207,GO:0043436,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0061605,GO:0070566,GO:0071704,GO:0071944,GO:0075136,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.73,2.7.7.80,2.8.1.11 ko:K03148,ko:K03636,ko:K21029,ko:K21147 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07459,R07461 RC00043 ko00000,ko00001,ko01000 - - - Rhodanese,ThiF,ThiS k141_22410_2 373994.Riv7116_3496 3.74e-13 68.9 COG1310@1|root,COG1310@2|Bacteria,1G7SZ@1117|Cyanobacteria,1HP7B@1161|Nostocales 1117|Cyanobacteria S PFAM Mov34 MPN PAD-1 family - - - - - - - - - - - - Prok-JAB k141_32921_2 1294265.JCM21738_1169 1.05e-34 121.0 2EUDS@1|root,33MW4@2|Bacteria,1VHIA@1239|Firmicutes,4HSFG@91061|Bacilli,1ZEP8@1386|Bacillus 91061|Bacilli S Sporulation inhibitor of replication protein sirA yneE - - - - - - - - - - - SirA k141_34213_1 218284.CCDN010000001_gene1362 1.89e-93 292.0 COG1193@1|root,COG1193@2|Bacteria,1TQWB@1239|Firmicutes,4HAHW@91061|Bacilli,1ZC6C@1386|Bacillus 91061|Bacilli L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity mutS1 - - ko:K07456 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_V k141_19995_1 322710.Avin_47850 4.26e-19 87.0 COG1741@1|root,COG1741@2|Bacteria,1MVSW@1224|Proteobacteria,1RNVS@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Belongs to the pirin family Z012_11830 - - ko:K06911 - - - - ko00000 - - - Pirin k141_19995_2 1453501.JELR01000002_gene1019 1.58e-53 174.0 COG0730@1|root,COG0730@2|Bacteria,1MVY3@1224|Proteobacteria,1S21M@1236|Gammaproteobacteria,467A8@72275|Alteromonadaceae 1236|Gammaproteobacteria S Sulfite exporter TauE/SafE - - - ko:K07090 - - - - ko00000 - - - TauE k141_23750_1 1286632.P278_31310 2.08e-46 169.0 28HMZ@1|root,2Z7WD@2|Bacteria,4P095@976|Bacteroidetes 2|Bacteria S Protein of unknown function (DUF3604) - - - - - - - - - - - - DUF3604 k141_29394_1 218284.CCDN010000002_gene2101 6.28e-40 140.0 COG2984@1|root,COG2984@2|Bacteria,1TPB0@1239|Firmicutes,4HESK@91061|Bacilli,1ZBBC@1386|Bacillus 91061|Bacilli S transport system, periplasmic component - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind k141_16329_3 1279017.AQYJ01000021_gene2826 2.34e-152 445.0 COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,1RPI1@1236|Gammaproteobacteria,466VC@72275|Alteromonadaceae 1236|Gammaproteobacteria M Biotin-lipoyl like - - - ko:K03585 ko01501,ko01503,map01501,map01503 M00646,M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,8.A.1.6 - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 k141_16329_4 1279017.AQYJ01000021_gene2827 1.05e-269 772.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,466AN@72275|Alteromonadaceae 1236|Gammaproteobacteria V AcrB/AcrD/AcrF family bepG - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran k141_11773_1 218284.CCDN010000002_gene2303 2.23e-89 269.0 COG1028@1|root,COG1028@2|Bacteria,1TRFB@1239|Firmicutes,4HBF8@91061|Bacilli,1ZB9T@1386|Bacillus 91061|Bacilli IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - - - - - - - - - - adh_short,adh_short_C2 k141_1931_1 1453501.JELR01000002_gene635 5.17e-176 518.0 COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,1RP9N@1236|Gammaproteobacteria,464DC@72275|Alteromonadaceae 1236|Gammaproteobacteria H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell glnE GO:0000166,GO:0000287,GO:0000820,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006521,GO:0006541,GO:0006542,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0008882,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0010565,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0019222,GO:0019752,GO:0030554,GO:0031323,GO:0032553,GO:0032555,GO:0032559,GO:0033238,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.42,2.7.7.89 ko:K00982 - - - - ko00000,ko01000 - - - GlnD_UR_UTase,GlnE k141_31534_1 1453501.JELR01000001_gene2062 8.55e-305 843.0 COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,1RNQ2@1236|Gammaproteobacteria,4640F@72275|Alteromonadaceae 1236|Gammaproteobacteria GM nucleoside-diphosphate sugar epimerases wbpM - - - - - - - - - - - CoA_binding_3,Polysacc_synt_2 k141_3214_1 42565.FP66_14075 5.89e-104 320.0 COG4774@1|root,COG4774@2|Bacteria,1QV5G@1224|Proteobacteria,1T298@1236|Gammaproteobacteria,1XRSG@135619|Oceanospirillales 135619|Oceanospirillales P Outer membrane protein beta-barrel family - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_36388_2 698758.AXY_11230 3.56e-13 68.9 2E87Y@1|root,332M1@2|Bacteria,1VHQ0@1239|Firmicutes,4HNRH@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - k141_12938_1 378806.STAUR_4873 1.62e-63 209.0 COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,42MSP@68525|delta/epsilon subdivisions,2WIUZ@28221|Deltaproteobacteria,2YTZB@29|Myxococcales 28221|Deltaproteobacteria E synthase homocitrate synthase family - - 2.3.3.13 ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 M00432 R01213 RC00004,RC00470,RC02754 br01601,ko00000,ko00001,ko00002,ko01000 - - - HMGL-like k141_28022_1 218284.CCDN010000007_gene3860 3.59e-102 328.0 COG1674@1|root,COG1674@2|Bacteria,1TRA4@1239|Firmicutes,4H9QM@91061|Bacilli,1ZDSN@1386|Bacillus 91061|Bacilli D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins essC - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FHA,FtsK_SpoIIIE,FtsK_SpoIIIE_N k141_19996_1 997296.PB1_17299 2.03e-151 439.0 COG1866@1|root,COG1866@2|Bacteria,1TPQV@1239|Firmicutes,4HAKG@91061|Bacilli,1ZCVN@1386|Bacillus 91061|Bacilli C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA pckA GO:0000166,GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0017076,GO:0019318,GO:0019319,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576 4.1.1.49 ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 M00003,M00170 R00341 RC00002,RC02741 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS09060,iYO844.BSU30560 PEPCK_ATP k141_35483_1 1453501.JELR01000002_gene577 8.8e-56 184.0 COG0683@1|root,COG0683@2|Bacteria,1MU8V@1224|Proteobacteria,1RMIJ@1236|Gammaproteobacteria,4654K@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component urtA - - ko:K11959 ko02010,map02010 M00323 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4.4,3.A.1.4.5 - - Peripla_BP_5 k141_35483_2 1453501.JELR01000002_gene576 1.37e-06 50.8 COG0559@1|root,COG0559@2|Bacteria,1MVND@1224|Proteobacteria,1RQXD@1236|Gammaproteobacteria,46515@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the binding-protein-dependent transport system permease family urtB - - ko:K11960 ko02010,map02010 M00323 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4.4,3.A.1.4.5 - - BPD_transp_2,HEAT_2 k141_22411_1 1121935.AQXX01000124_gene77 8.97e-94 278.0 2DKHM@1|root,309GY@2|Bacteria,1RFJ6@1224|Proteobacteria,1S4EG@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_9402_2 1453501.JELR01000002_gene1494 7.91e-135 388.0 COG3672@1|root,COG3672@2|Bacteria,1RKG9@1224|Proteobacteria,1S8MS@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Periplasmic Protein - - - - - - - - - - - - Transglut_core k141_9402_4 1453501.JELR01000002_gene1496 5.19e-164 464.0 COG0330@1|root,COG0330@2|Bacteria,1MX2I@1224|Proteobacteria 1224|Proteobacteria O COG0330 Membrane protease subunits stomatin prohibitin homologs - - - - - - - - - - - - Band_7 k141_20972_2 218284.CCDN010000005_gene3468 2.01e-125 369.0 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli,1ZAY9@1386|Bacillus 91061|Bacilli C Belongs to the aldehyde dehydrogenase family acoD - - ko:K00138 ko00010,ko00620,ko01100,ko01110,ko01120,map00010,map00620,map01100,map01110,map01120 - R00711 RC00047 ko00000,ko00001,ko01000 - - - Aldedh k141_5760_1 1042377.AFPJ01000042_gene1073 6.26e-195 564.0 COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,1RNCM@1236|Gammaproteobacteria,464B9@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs iorB - 1.3.99.16 ko:K07303 - - - - ko00000,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2,TAT_signal k141_23751_1 1294265.JCM21738_4231 3.36e-109 334.0 COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,4H9RD@91061|Bacilli,1ZBEP@1386|Bacillus 91061|Bacilli C formate acetyltransferase pflB GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006566,GO:0006567,GO:0006807,GO:0008150,GO:0008152,GO:0008861,GO:0009056,GO:0009063,GO:0009066,GO:0009068,GO:0009987,GO:0016054,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.3.1.54 ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 - R00212,R06987 RC00004,RC01181,RC02742,RC02833 ko00000,ko00001,ko01000 - - - Gly_radical,PFL-like k141_3215_1 42565.FP66_08840 9.98e-108 317.0 COG0524@1|root,COG0524@2|Bacteria,1MV6I@1224|Proteobacteria,1RSHQ@1236|Gammaproteobacteria,1XMEY@135619|Oceanospirillales 135619|Oceanospirillales G pfkB family carbohydrate kinase - - 2.7.1.13,2.7.1.45 ko:K00874,ko:K11441 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 M00061,M00308,M00631 R01541,R02658 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - PfkB k141_9403_1 1134413.ANNK01000164_gene657 9.23e-38 137.0 COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,4HAPA@91061|Bacilli,1ZBBG@1386|Bacillus 91061|Bacilli C alcohol dehydrogenase - - - ko:K19954 - - - - ko00000,ko01000 - - - Fe-ADH k141_36389_1 203122.Sde_0007 7.05e-44 146.0 COG3296@1|root,COG3296@2|Bacteria,1RET3@1224|Proteobacteria,1S4H0@1236|Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria - - - ko:K09940 - - - - ko00000 - - - DUF4870 k141_31536_1 1294265.JCM21738_1209 3.25e-117 341.0 COG0179@1|root,COG0179@2|Bacteria,1UY98@1239|Firmicutes,4HC89@91061|Bacilli,1ZCD1@1386|Bacillus 91061|Bacilli Q Fumarylacetoacetate (FAA) hydrolase family - - 3.7.1.2 ko:K16171 ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120 M00044 R01364 RC00326,RC00446 ko00000,ko00001,ko00002,ko01000 - - - FAA_hydrolase k141_26039_1 545693.BMQ_2701 1.76e-49 180.0 COG0737@1|root,COG0737@2|Bacteria,1TPV2@1239|Firmicutes,4HB9S@91061|Bacilli,1ZAY0@1386|Bacillus 91061|Bacilli F Belongs to the 5'-nucleotidase family yhcR - 3.1.3.5,3.1.3.6,3.1.4.16 ko:K01081,ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01562,R01569,R01664,R01877,R01968,R02088,R02102,R02148,R02323,R02370,R02719,R03346,R03537,R03538,R03929,R05135 RC00017,RC00078,RC00296 ko00000,ko00001,ko01000 - - - 5_nucleotid_C,Gram_pos_anchor,LTD,Metallophos,SLH,SNase k141_34215_1 218284.CCDN010000002_gene2024 2.42e-121 351.0 COG0500@1|root,COG2226@2|Bacteria,1UIWS@1239|Firmicutes,4HIDW@91061|Bacilli,1ZQ1R@1386|Bacillus 91061|Bacilli Q ubiE/COQ5 methyltransferase family - - - - - - - - - - - - Methyltransf_11 k141_24724_1 218284.CCDN010000002_gene2109 5.89e-118 353.0 COG1249@1|root,COG1249@2|Bacteria,1UYJP@1239|Firmicutes,4HCWF@91061|Bacilli,1ZED9@1386|Bacillus 91061|Bacilli C Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain - - 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyr_redox_2,Pyr_redox_dim k141_16330_1 1294265.JCM21738_4193 1.56e-35 137.0 29SR4@1|root,30DX0@2|Bacteria,1V1H9@1239|Firmicutes,4HFRK@91061|Bacilli,1ZD7U@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF4179) - - - - - - - - - - - - DUF4179 k141_16330_2 573061.Clocel_0950 7.58e-12 64.7 COG1595@1|root,COG1595@2|Bacteria,1V734@1239|Firmicutes,24MQB@186801|Clostridia,36KKI@31979|Clostridiaceae 186801|Clostridia K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_22413_2 218284.CCDN010000008_gene4200 1.43e-43 143.0 2E43M@1|root,32YZY@2|Bacteria,1VAYB@1239|Firmicutes,4HNNI@91061|Bacilli,1ZHTZ@1386|Bacillus 91061|Bacilli S YtzH-like protein ytzH - - - - - - - - - - - YtzH k141_24745_1 935837.JAEK01000040_gene3721 7.97e-92 290.0 COG2200@1|root,COG3300@1|root,COG2200@2|Bacteria,COG3300@2|Bacteria,1TS8B@1239|Firmicutes,4ISKA@91061|Bacilli,1ZDC3@1386|Bacillus 91061|Bacilli T Bacterial signalling protein N terminal repeat - - 2.7.7.65 ko:K21023 ko02025,map02025 - - - ko00000,ko00001,ko01000 - - - EAL,GAF,GGDEF,MASE3,MHYT,PAS_4,PAS_9 k141_1076_1 697284.ERIC2_c26940 1.53e-80 256.0 COG0749@1|root,COG0749@2|Bacteria,1UYWH@1239|Firmicutes,4HEST@91061|Bacilli,26W8S@186822|Paenibacillaceae 91061|Bacilli L DNA polymerase family A - - - - - - - - - - - - DNA_pol_A,DNA_pol_A_exo1 k141_20011_1 1294265.JCM21738_431 5.97e-86 265.0 COG3420@1|root,COG3420@2|Bacteria,1UN63@1239|Firmicutes,4HDJ8@91061|Bacilli,1ZRYJ@1386|Bacillus 91061|Bacilli P Periplasmic copper-binding protein (NosD) nosD - - ko:K07218 - - - - ko00000 - - - NosD k141_37628_1 1122947.FR7_3126 6.34e-12 65.5 COG0001@1|root,COG0001@2|Bacteria,1TPNH@1239|Firmicutes,4H25J@909932|Negativicutes 909932|Negativicutes H Glutamate-1-semialdehyde hemL - 5.4.3.8 ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02272 RC00677 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 k141_37628_2 172088.AUGA01000056_gene4671 0.000475 45.1 COG1835@1|root,COG1835@2|Bacteria,1N2Z2@1224|Proteobacteria,2U1IQ@28211|Alphaproteobacteria,3JRAD@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I Acyltransferase family - - - - - - - - - - - - Acyl_transf_3 k141_24746_1 218284.CCDN010000008_gene4095 3.74e-117 348.0 COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli,1ZB5X@1386|Bacillus 91061|Bacilli G phosphotransferase system treP GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0015766,GO:0015771,GO:0015772,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563,GO:0090589 2.7.1.201 ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 M00270 R02780 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.13,4.A.1.2.4,4.A.1.2.8 - iYO844.BSU07800 PTS_EIIA_1,PTS_EIIB,PTS_EIIC k141_11808_1 748727.CLJU_c31720 1.84e-07 53.5 COG1476@1|root,COG1476@2|Bacteria,1VEKB@1239|Firmicutes,25EYA@186801|Clostridia,36UZN@31979|Clostridiaceae 186801|Clostridia K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_19,HTH_3 k141_11808_3 1196324.A374_08984 2.38e-181 519.0 COG1961@1|root,COG1961@2|Bacteria,1TPUG@1239|Firmicutes,4HB3H@91061|Bacilli 91061|Bacilli L COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - - - - - - - - - - Recombinase,Resolvase,Zn_ribbon_recom k141_23772_2 1116375.VEJY3_16716 1.8e-129 373.0 COG4302@1|root,COG4302@2|Bacteria,1MWQI@1224|Proteobacteria,1RQ2T@1236|Gammaproteobacteria,1XVCN@135623|Vibrionales 135623|Vibrionales H Ethanolamine ammonia-lyase light chain (EutC) - - 4.3.1.7 ko:K03736 ko00564,ko01100,map00564,map01100 - R00749 RC00370 ko00000,ko00001,ko01000 - - - EutC k141_1964_1 218284.CCDN010000001_gene1591 4.49e-173 488.0 COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,4HA4E@91061|Bacilli,1ZB72@1386|Bacillus 91061|Bacilli P Belongs to the ABC transporter superfamily dppD - - ko:K16202 ko02010,map02010 M00566 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.2 - - ABC_tran,oligo_HPY k141_1964_2 218284.CCDN010000001_gene1590 6.83e-09 56.6 COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,4HAMK@91061|Bacilli,1ZBB4@1386|Bacillus 91061|Bacilli E ABC transporter substrate-binding protein dppE GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 - ko:K16199 ko02010,map02010 M00566 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.2 - - SBP_bac_5 k141_3238_1 406124.ACPC01000046_gene2409 2.73e-34 143.0 COG1404@1|root,COG1404@2|Bacteria,1TPH1@1239|Firmicutes,4HBQH@91061|Bacilli,1ZBS0@1386|Bacillus 91061|Bacilli O Belongs to the peptidase S8 family prtS - 3.4.21.110,3.4.21.96 ko:K01361,ko:K08652 - - - - ko00000,ko01000,ko01002,ko03110 - - - FIVAR,Gram_pos_anchor,Inhibitor_I9,PA,Peptidase_S8,SLH,YSIRK_signal,fn3_5 k141_15116_1 1517681.HW45_05860 1.55e-245 683.0 COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,1RQ7D@1236|Gammaproteobacteria,1XSW2@135623|Vibrionales 135623|Vibrionales E Asparagine synthetase B asnB - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 k141_15116_2 1116375.VEJY3_03760 7.11e-47 163.0 COG1226@1|root,COG4651@1|root,COG1226@2|Bacteria,COG4651@2|Bacteria,1MV34@1224|Proteobacteria,1RNH4@1236|Gammaproteobacteria,1XV3J@135623|Vibrionales 135623|Vibrionales P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family - - - - - - - - - - - - Na_H_Exchanger,TrkA_N k141_16352_1 1279017.AQYJ01000019_gene1495 4.21e-128 387.0 COG0642@1|root,COG0642@2|Bacteria,1QU3Z@1224|Proteobacteria,1T311@1236|Gammaproteobacteria,46D2F@72275|Alteromonadaceae 1236|Gammaproteobacteria T Histidine kinase - - - - - - - - - - - - CBM9_1,HATPase_c,HisKA k141_7046_2 198467.NP92_09370 5.81e-30 112.0 COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,4HAK4@91061|Bacilli,21V99@150247|Anoxybacillus 91061|Bacilli J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release rplA GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02863 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L1 k141_36412_1 218284.CCDN010000007_gene3906 1.64e-148 423.0 COG0451@1|root,COG0451@2|Bacteria,1TSUN@1239|Firmicutes,4HA3D@91061|Bacilli,1ZAUE@1386|Bacillus 91061|Bacilli GM GDP-mannose 4,6 dehydratase - - - - - - - - - - - - Epimerase k141_35512_1 1219076.N646_1931 8.28e-79 234.0 COG3029@1|root,COG3029@2|Bacteria,1MZ4C@1224|Proteobacteria,1SC0P@1236|Gammaproteobacteria,1XXFQ@135623|Vibrionales 135623|Vibrionales C Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane frdC GO:0000104,GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0016627,GO:0044237,GO:0045333,GO:0055114 - ko:K00246 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00150,M00173 R02164 RC00045 ko00000,ko00001,ko00002 - - - Fumarate_red_C k141_35512_2 55601.VANGNB10_cI2407 2.32e-182 507.0 COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,1RNWR@1236|Gammaproteobacteria,1XTYJ@135623|Vibrionales 135623|Vibrionales C Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family frdB - 1.3.5.4 ko:K00245 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00150,M00173 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - Fer2_3,Fer4_8 k141_35512_3 223926.28807866 0.0 1169.0 COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,1RMU2@1236|Gammaproteobacteria,1XSH4@135623|Vibrionales 135623|Vibrionales C fumarate reductase, flavoprotein subunit frdA - 1.3.5.4 ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00150,M00173 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C k141_34232_1 1116375.VEJY3_05600 6.36e-96 290.0 COG3434@1|root,COG3434@2|Bacteria,1MVW1@1224|Proteobacteria,1RS25@1236|Gammaproteobacteria,1XTJ5@135623|Vibrionales 135623|Vibrionales T signal transduction protein containing EAL and modified HD-GYP domains - - - - - - - - - - - - EAL,HDOD k141_29418_1 1209072.ALBT01000011_gene3136 6.63e-18 81.3 COG0755@1|root,COG0755@2|Bacteria,1MU61@1224|Proteobacteria,1RP3R@1236|Gammaproteobacteria,1FGAS@10|Cellvibrio 1236|Gammaproteobacteria O Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes ccmC GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008152,GO:0015886,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051181,GO:0051234,GO:0055114,GO:0071702,GO:0071705,GO:0071944,GO:1901678 - ko:K02195 ko02010,map02010 M00259 - - ko00000,ko00001,ko00002,ko02000 3.A.1.107 - iECDH1ME8569_1439.ECDH1ME8569_2134,iSFV_1184.SFV_2275,iSFxv_1172.SFxv_2517,iUTI89_1310.UTI89_C2477,ic_1306.c2736 Cytochrom_C_asm k141_29418_2 1453501.JELR01000001_gene2676 5.13e-15 70.1 COG3114@1|root,COG3114@2|Bacteria 2|Bacteria U Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes ccmD GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0009898,GO:0015886,GO:0016020,GO:0031224,GO:0031226,GO:0031235,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051181,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0098552,GO:0098562,GO:1901678 - ko:K02196 ko02010,map02010 - - - ko00000,ko00001,ko02000 3.A.1.107 - iB21_1397.B21_02084,iBWG_1329.BWG_1971,iE2348C_1286.E2348C_2342,iEC042_1314.EC042_2439,iEC55989_1330.EC55989_2451,iECABU_c1320.ECABU_c25320,iECBD_1354.ECBD_1462,iECB_1328.ECB_02125,iECDH10B_1368.ECDH10B_2355,iECDH1ME8569_1439.ECDH1ME8569_2133,iECD_1391.ECD_02125,iECED1_1282.ECED1_2663,iECH74115_1262.ECH74115_3335,iECIAI1_1343.ECIAI1_2280,iECIAI39_1322.ECIAI39_2336,iECNA114_1301.ECNA114_2290,iECO103_1326.ECO103_2673,iECO111_1330.ECO111_2934,iECO26_1355.ECO26_3124,iECOK1_1307.ECOK1_2432,iECP_1309.ECP_2238,iECS88_1305.ECS88_2345,iECSE_1348.ECSE_2466,iECSF_1327.ECSF_2079,iECSP_1301.ECSP_3077,iECUMN_1333.ECUMN_2533,iECs_1301.ECs3087,iEKO11_1354.EKO11_1558,iETEC_1333.ETEC_2332,iEcDH1_1363.EcDH1_1461,iEcE24377_1341.EcE24377A_2497,iEcHS_1320.EcHS_A2336,iEcSMS35_1347.EcSMS35_2346,iEcolC_1368.EcolC_1452,iJO1366.b2198,iLF82_1304.LF82_0276,iNRG857_1313.NRG857_11155,iSDY_1059.SDY_0880,iSFV_1184.SFV_2274,iSF_1195.SF2282,iSSON_1240.SSON_2256,iS_1188.S2412,iUMN146_1321.UM146_05815,iUMNK88_1353.UMNK88_2745,iUTI89_1310.UTI89_C2476,iY75_1357.Y75_RS11500,iZ_1308.Z3455,ic_1306.c2735 CcmD k141_29418_4 1042377.AFPJ01000036_gene1245 1.47e-121 366.0 COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,1RMY5@1236|Gammaproteobacteria,4649T@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG1138 Cytochrome c biogenesis factor ccmF GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0019538,GO:0020037,GO:0022607,GO:0031224,GO:0031226,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046906,GO:0048037,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564 - ko:K02198 - - - - ko00000,ko02000 9.B.14.1 - - CcmF_C,Cytochrom_C_asm k141_10481_1 1279017.AQYJ01000028_gene2040 2.32e-26 104.0 2DBVC@1|root,2ZBAF@2|Bacteria,1PT3T@1224|Proteobacteria,1RZJK@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Psort location CytoplasmicMembrane, score 9.46 - - - - - - - - - - - - - k141_10481_2 1042377.AFPJ01000028_gene2190 7.27e-151 434.0 COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,1RN5Z@1236|Gammaproteobacteria,46525@72275|Alteromonadaceae 1236|Gammaproteobacteria S permease VP2476 - - - - - - - - - - - AI-2E_transport k141_22436_2 1348635.BBJY01000008_gene1750 4.56e-224 629.0 COG0714@1|root,COG0714@2|Bacteria,1QUGB@1224|Proteobacteria,1T1Y2@1236|Gammaproteobacteria,1XSEK@135623|Vibrionales 135623|Vibrionales S ATPase with chaperone activity - - - - - - - - - - - - - k141_22436_3 945550.VISI1226_15791 2.28e-25 103.0 COG4960@1|root,COG4960@2|Bacteria,1QKFB@1224|Proteobacteria,1TIJ8@1236|Gammaproteobacteria,1XZ89@135623|Vibrionales 135623|Vibrionales OU COG4960 Flp pilus assembly protein, protease CpaA - - 3.4.23.43 ko:K02278 - - - - ko00000,ko01000,ko02035,ko02044 - - - Peptidase_A24 k141_22436_4 550540.Fbal_2353 4.75e-13 64.3 2ETEB@1|root,33KY5@2|Bacteria,1NPIT@1224|Proteobacteria,1SHS9@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - ko:K02651 ko04112,map04112 - - - ko00000,ko00001,ko02035,ko02044 - - - - k141_36620_5 1280001.BAOA01000060_gene2314 2.21e-172 481.0 COG4106@1|root,COG4106@2|Bacteria,1QTS9@1224|Proteobacteria,1T1FG@1236|Gammaproteobacteria,1XSJZ@135623|Vibrionales 135623|Vibrionales H Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM) cmoA - - ko:K15256 - - - - ko00000,ko01000,ko03016 - - - Methyltransf_11,Methyltransf_25 k141_36620_6 1116375.VEJY3_04870 1.18e-196 546.0 COG1801@1|root,COG1801@2|Bacteria,1MU7F@1224|Proteobacteria,1RSAG@1236|Gammaproteobacteria,1XUWW@135623|Vibrionales 135623|Vibrionales S Protein of unknown function DUF72 yecE - - - - - - - - - - - DUF72 k141_36620_7 674977.VMC_31620 0.0 1134.0 COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,1RNMI@1236|Gammaproteobacteria,1XSZA@135623|Vibrionales 135623|Vibrionales J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) aspS GO:0003674,GO:0003824,GO:0004812,GO:0004815,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006422,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - GAD,tRNA-synt_2,tRNA_anti-codon k141_36620_8 223926.28806035 1.19e-111 322.0 COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,1RQPJ@1236|Gammaproteobacteria,1XT73@135623|Vibrionales 135623|Vibrionales L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group ruvC GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 ko:K01159 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvC k141_21328_1 1042377.AFPJ01000007_gene1844 2.12e-06 48.5 COG3291@1|root,COG3291@2|Bacteria,1QU15@1224|Proteobacteria,1T1KN@1236|Gammaproteobacteria,46D2W@72275|Alteromonadaceae 1236|Gammaproteobacteria S Pkd domain containing protein - - - - - - - - - - - - - k141_17818_1 1499680.CCFE01000016_gene1182 6.59e-69 222.0 COG3069@1|root,COG3069@2|Bacteria,1U0AJ@1239|Firmicutes,4HB8W@91061|Bacilli 91061|Bacilli C C4-dicarboxylate anaerobic carrier dcuC - - ko:K03326 - - - - ko00000,ko02000 2.A.61.1 - - DcuC k141_4706_1 1294265.JCM21738_3249 1.47e-73 225.0 COG0454@1|root,COG0456@2|Bacteria,1V47B@1239|Firmicutes,4HHAS@91061|Bacilli,1ZI27@1386|Bacillus 91061|Bacilli K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031248,GO:0031365,GO:0032991,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564,GO:1902493,GO:1902494,GO:1990234 - - - - - - - - - - Acetyltransf_1 k141_37947_1 1396858.Q666_09400 1.02e-105 337.0 COG1061@1|root,COG2227@1|root,COG2932@1|root,COG3886@1|root,COG1061@2|Bacteria,COG2227@2|Bacteria,COG2932@2|Bacteria,COG3886@2|Bacteria,1MV9F@1224|Proteobacteria,1RNAN@1236|Gammaproteobacteria,4657B@72275|Alteromonadaceae 1236|Gammaproteobacteria L type III restriction enzyme, res subunit - - - - - - - - - - - - DUF3427,Helicase_C,Methyltransf_25,PLDc_2,ResIII k141_8149_1 218284.CCDN010000004_gene3089 7.55e-194 547.0 COG0388@1|root,COG3153@1|root,COG0388@2|Bacteria,COG3153@2|Bacteria,1TQAZ@1239|Firmicutes,4HCQW@91061|Bacilli,1ZB16@1386|Bacillus 91061|Bacilli K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase yhcX - - - - - - - - - - - Acetyltransf_1,CN_hydrolase k141_21329_1 1453501.JELR01000002_gene748 7.53e-28 103.0 2EU5W@1|root,33MNG@2|Bacteria,1NPY2@1224|Proteobacteria,1SI8X@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - ko:K06080 ko02020,map02020 - - - ko00000,ko00001 - - - - k141_21329_2 1453501.JELR01000001_gene2495 1.62e-34 131.0 COG0116@1|root,COG1092@1|root,COG0116@2|Bacteria,COG1092@2|Bacteria,1MUQM@1224|Proteobacteria,1RNMH@1236|Gammaproteobacteria,4657X@72275|Alteromonadaceae 1236|Gammaproteobacteria J Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA rlmL GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.173,2.1.1.264 ko:K12297 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - Methyltrans_SAM,THUMP,UPF0020 k141_3502_2 1116375.VEJY3_20311 1.88e-306 837.0 COG0443@1|root,COG0443@2|Bacteria,1MXBT@1224|Proteobacteria,1RN4U@1236|Gammaproteobacteria,1XU0W@135623|Vibrionales 135623|Vibrionales O COG0443 Molecular chaperone T0747 - - ko:K04046 - - - - ko00000,ko03110 1.A.33 - - HSP70 k141_3502_3 1280001.BAOA01000010_gene4218 1.17e-103 304.0 2AVVA@1|root,31MP3@2|Bacteria,1QJGQ@1224|Proteobacteria,1THGK@1236|Gammaproteobacteria,1XVP5@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_2321_1 218284.CCDN010000004_gene3106 4.24e-118 343.0 COG1230@1|root,COG1230@2|Bacteria,1TR92@1239|Firmicutes,4HBCQ@91061|Bacilli,1ZB56@1386|Bacillus 91061|Bacilli P COG1230 Co Zn Cd efflux system component czcD - - ko:K16264 - - - - ko00000,ko02000 2.A.4.1 - - Cation_efflux k141_17819_1 649638.Trad_2704 9.56e-61 197.0 COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria,1WIR2@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus K Iron dependent repressor, metal binding and dimerisation domain - - - ko:K03709 - - - - ko00000,ko03000 - - - Fe_dep_repr_C,Fe_dep_repress,FeoA k141_17819_2 992406.RIA_0486 4.61e-09 56.2 COG2096@1|root,COG2096@2|Bacteria,4NFHQ@976|Bacteroidetes,1HX1J@117743|Flavobacteriia 976|Bacteroidetes S adenosyltransferase yvqK - 2.5.1.17 ko:K00798 ko00860,ko01100,map00860,map01100 M00122 R01492,R05220,R07268 RC00533 ko00000,ko00001,ko00002,ko01000 - - - Cob_adeno_trans k141_4708_1 1035191.HMPREF0185_02869 1.1e-14 74.3 COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,2TSHK@28211|Alphaproteobacteria,2KFB5@204458|Caulobacterales 204458|Caulobacterales E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine trpB - 4.2.1.20 ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - PALP k141_4708_2 228405.HNE_3477 1.12e-15 76.6 COG0135@1|root,COG0135@2|Bacteria,1RA87@1224|Proteobacteria,2U7CH@28211|Alphaproteobacteria,43Y03@69657|Hyphomonadaceae 28211|Alphaproteobacteria E Belongs to the TrpF family trpF - 5.3.1.24 ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03509 RC00945 ko00000,ko00001,ko00002,ko01000 - - - PRAI k141_30617_2 1453501.JELR01000002_gene1134 1.48e-139 405.0 COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,1RRA1@1236|Gammaproteobacteria,4641H@72275|Alteromonadaceae 1236|Gammaproteobacteria S esterase of the alpha-beta hydrolase superfamily rssA GO:0003674,GO:0003824,GO:0016787 - ko:K07001 - - - - ko00000 - - - Patatin k141_30617_3 1279017.AQYJ01000027_gene1820 9.75e-81 241.0 COG0355@1|root,COG0355@2|Bacteria,1RHE4@1224|Proteobacteria,1S25H@1236|Gammaproteobacteria,4679J@72275|Alteromonadaceae 1236|Gammaproteobacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane atpC GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - iJN746.PP_5412 ATP-synt_DE,ATP-synt_DE_N k141_30617_4 1042377.AFPJ01000012_gene1326 7.27e-314 858.0 COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,1RN6U@1236|Gammaproteobacteria,465I5@72275|Alteromonadaceae 1236|Gammaproteobacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits atpD GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - e_coli_core.b3732,iAF1260.b3732,iAPECO1_1312.APECO1_2729,iB21_1397.B21_03560,iBWG_1329.BWG_3423,iE2348C_1286.E2348C_4042,iEC042_1314.EC042_4119,iEC55989_1330.EC55989_4207,iECABU_c1320.ECABU_c42160,iECBD_1354.ECBD_4300,iECB_1328.ECB_03616,iECDH10B_1368.ECDH10B_3919,iECDH1ME8569_1439.ECDH1ME8569_3620,iECD_1391.ECD_03616,iECED1_1282.ECED1_4422,iECH74115_1262.ECH74115_5168,iECIAI1_1343.ECIAI1_3916,iECIAI39_1322.ECIAI39_4336,iECNA114_1301.ECNA114_3881,iECO103_1326.ECO103_4426,iECO111_1330.ECO111_4566,iECO26_1355.ECO26_4846,iECOK1_1307.ECOK1_4181,iECP_1309.ECP_3931,iECS88_1305.ECS88_4154,iECSE_1348.ECSE_4022,iECSF_1327.ECSF_3580,iECSP_1301.ECSP_4782,iECUMN_1333.ECUMN_4262,iECW_1372.ECW_m4035,iECs_1301.ECs4674,iEKO11_1354.EKO11_4613,iETEC_1333.ETEC_4023,iEcDH1_1363.EcDH1_4235,iEcE24377_1341.EcE24377A_4247,iEcSMS35_1347.EcSMS35_4100,iEcolC_1368.EcolC_4262,iG2583_1286.G2583_4528,iJO1366.b3732,iJR904.b3732,iLF82_1304.LF82_0194,iNRG857_1313.NRG857_18585,iPC815.YPO4121,iSFV_1184.SFV_3758,iSF_1195.SF3812,iSFxv_1172.SFxv_4154,iSSON_1240.SSON_3887,iS_1188.S3956,iSbBS512_1146.SbBS512_E4189,iUMN146_1321.UM146_18850,iUMNK88_1353.UMNK88_4544,iUTI89_1310.UTI89_C4285,iWFL_1372.ECW_m4035,iY75_1357.Y75_RS18410,iZ_1308.Z5230,ic_1306.c4658 ATP-synt_ab,ATP-synt_ab_N k141_36623_1 1042377.AFPJ01000037_gene2891 3.09e-162 467.0 COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,1RMU9@1236|Gammaproteobacteria,46456@72275|Alteromonadaceae 1236|Gammaproteobacteria U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components ffh GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006605,GO:0006612,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046907,GO:0048500,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1990904 3.6.5.4 ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko01000,ko02044 3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9 - - SRP54,SRP54_N,SRP_SPB k141_37949_1 218284.CCDN010000002_gene2130 2.48e-69 224.0 COG4191@1|root,COG4191@2|Bacteria,1VCNJ@1239|Firmicutes,4HVBX@91061|Bacilli,1ZS41@1386|Bacillus 91061|Bacilli T Histidine kinase - - 2.7.13.3 ko:K02491,ko:K13533 ko02020,map02020 M00485 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - 5TM-5TMR_LYT,HATPase_c,HisKA,LytTR,MASE3,PAS,PAS_3,PAS_4,PAS_9 k141_4709_1 1116375.VEJY3_21746 1.19e-07 52.0 COG0010@1|root,COG0010@2|Bacteria,1QJHE@1224|Proteobacteria,1THHA@1236|Gammaproteobacteria,1XVV5@135623|Vibrionales 135623|Vibrionales E COG0010 Arginase agmatinase formimionoglutamate hydrolase, arginase family - - - - - - - - - - - - Arginase k141_33248_1 870187.Thini_2679 7.76e-44 149.0 COG4657@1|root,COG4657@2|Bacteria,1MU8X@1224|Proteobacteria,1RQDN@1236|Gammaproteobacteria,4604J@72273|Thiotrichales 1236|Gammaproteobacteria C Part of a membrane complex involved in electron transport rnfA - - ko:K03617 - - - - ko00000 - - - Rnf-Nqr k141_3503_2 390235.PputW619_0135 5.86e-101 310.0 COG1027@1|root,COG1027@2|Bacteria,1R9JY@1224|Proteobacteria,1RP5Z@1236|Gammaproteobacteria,1YXWR@136845|Pseudomonas putida group 1236|Gammaproteobacteria E Aspartate ammonia-lyase aspA - 4.3.1.1 ko:K01744 ko00250,ko01100,map00250,map01100 - R00490 RC00316,RC02799 ko00000,ko00001,ko01000 - - - FumaraseC_C,Lyase_1 k141_36624_1 1294265.JCM21738_4188 3.59e-79 239.0 COG0345@1|root,COG0345@2|Bacteria,1TP1E@1239|Firmicutes,4H9RV@91061|Bacilli,1ZCWZ@1386|Bacillus 91061|Bacilli E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline proC - 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 - - - F420_oxidored,P5CR_dimer k141_28374_1 1122201.AUAZ01000023_gene3026 3.46e-81 258.0 COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,1SYC8@1236|Gammaproteobacteria,46CYH@72275|Alteromonadaceae 1236|Gammaproteobacteria U Sulfate permease family - - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - STAS,STAS_2,Sulfate_transp k141_17821_1 218284.CCDN010000006_gene3530 6.45e-102 304.0 2DH6Y@1|root,2ZYKQ@2|Bacteria,1V3RR@1239|Firmicutes,4HHKE@91061|Bacilli,1ZBHI@1386|Bacillus 91061|Bacilli S Spore germination B3/ GerAC like, C-terminal - - - ko:K06308 - - - - ko00000 - - - Spore_GerAC k141_17821_2 218284.CCDN010000006_gene3531 8.15e-16 75.9 COG0673@1|root,COG0673@2|Bacteria,1TR8S@1239|Firmicutes,4HBHI@91061|Bacilli,1ZDU7@1386|Bacillus 91061|Bacilli S Oxidoreductase yvaA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0070401,GO:0070402,GO:0097159,GO:0102497,GO:1901265,GO:1901363 1.1.1.371 ko:K16044 ko00562,ko01120,map00562,map01120 - R09954 RC00182 ko00000,ko00001,ko01000 - - - GFO_IDH_MocA,GFO_IDH_MocA_C k141_2323_1 218284.CCDN010000005_gene3353 7.55e-129 395.0 COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,4HAFP@91061|Bacilli,1ZBJ3@1386|Bacillus 91061|Bacilli V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran k141_30619_2 1385513.N780_15745 1.34e-45 156.0 2CFXT@1|root,2ZAIF@2|Bacteria,1UZMK@1239|Firmicutes,4HDP0@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - Adenyl_transf,NTP_transf_2 k141_21396_1 653733.Selin_1029 2.96e-55 188.0 COG0306@1|root,COG0306@2|Bacteria 2|Bacteria P phosphate transporter pitA GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661 - ko:K03306 - - - - ko00000 2.A.20 - - PHO4 k141_36695_2 941639.BCO26_0878 1.55e-10 63.2 COG0454@1|root,COG0456@2|Bacteria,1VM6C@1239|Firmicutes,4IKX6@91061|Bacilli,1ZI62@1386|Bacillus 91061|Bacilli K Acetyltransferase (GNAT) domain - - 2.3.1.128 ko:K03789 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_1 k141_36695_3 1385514.N782_04275 1.89e-53 179.0 COG2340@1|root,COG2340@2|Bacteria,1V6FY@1239|Firmicutes,4HJ44@91061|Bacilli,2YA78@289201|Pontibacillus 91061|Bacilli S Cysteine-rich secretory protein family - - - - - - - - - - - - CAP k141_28439_1 1305836.AXVE01000012_gene129 4.41e-08 50.4 2E6HR@1|root,33150@2|Bacteria,1VF6G@1239|Firmicutes 1239|Firmicutes S YCII-related domain - - - - - - - - - - - - YCII k141_28439_2 218284.CCDN010000001_gene1950 8.44e-220 609.0 COG2334@1|root,COG2334@2|Bacteria,1TSRC@1239|Firmicutes,4HEJ3@91061|Bacilli,1ZEJM@1386|Bacillus 91061|Bacilli S homoserine kinase type II (protein kinase fold) yerI - - - - - - - - - - - APH k141_28439_3 218284.CCDN010000001_gene1949 4.69e-15 68.2 2B1JX@1|root,31U1A@2|Bacteria,1UCU4@1239|Firmicutes,4IPAA@91061|Bacilli,1ZPMC@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_31802_1 1078085.HMPREF1210_03099 9.57e-185 555.0 COG1404@1|root,COG1404@2|Bacteria,1TPH1@1239|Firmicutes,4HBQH@91061|Bacilli,26GW2@186818|Planococcaceae 91061|Bacilli O Peptidase inhibitor I9 prtS - 3.4.21.110,3.4.21.96 ko:K01361,ko:K08652 - - - - ko00000,ko01000,ko01002,ko03110 - - - FIVAR,Gram_pos_anchor,Inhibitor_I9,PA,Peptidase_S8,SLH,YSIRK_signal,fn3_5 k141_28440_1 1042377.AFPJ01000013_gene1739 2.54e-69 215.0 COG0791@1|root,COG0791@2|Bacteria,1N0EE@1224|Proteobacteria,1RR2X@1236|Gammaproteobacteria,4683S@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0791 Cell wall-associated hydrolases (invasion-associated proteins) nlpC - 3.4.17.13 ko:K13694,ko:K13695 - - - - ko00000,ko01000,ko01002,ko01011 - - - NLPC_P60 k141_21398_2 218284.CCDN010000005_gene3403 1.24e-41 142.0 2B51H@1|root,31XUS@2|Bacteria,1V6KA@1239|Firmicutes,4HKBP@91061|Bacilli,1ZFY9@1386|Bacillus 91061|Bacilli S Sporulation protein YunB (Spo_YunB) yunB - - - - - - - - - - - Spore_YunB k141_8201_1 406817.XNC1_4250 1.11e-05 45.4 COG3311@1|root,COG3311@2|Bacteria,1NGB9@1224|Proteobacteria,1SCF2@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology alpA - - ko:K07733 - - - - ko00000,ko03000 - - - Phage_AlpA k141_8201_2 1217710.F969_01528 9.85e-45 167.0 COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,1RMJ1@1236|Gammaproteobacteria,3NKDU@468|Moraxellaceae 1236|Gammaproteobacteria L Arm DNA-binding domain - - - - - - - - - - - - Arm-DNA-bind_3,Phage_int_SAM_3,Phage_integrase k141_8201_3 1280001.BAOA01000031_gene5169 1.53e-100 291.0 2940Y@1|root,2ZRFS@2|Bacteria,1RF8A@1224|Proteobacteria,1RZCB@1236|Gammaproteobacteria,1XX6B@135623|Vibrionales 135623|Vibrionales U L-alanine exporter AlaE alaE - - - - - - - - - - - AlaE k141_31803_1 493475.GARC_4048 3.66e-14 72.4 COG1250@1|root,COG1250@2|Bacteria,1MV8M@1224|Proteobacteria,1RSQP@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine lcdH - 1.1.1.108 ko:K17735 - - - - ko00000,ko01000 - - - 3HCDH,3HCDH_N k141_31803_2 596151.DesfrDRAFT_2558 3.18e-05 48.9 COG0500@1|root,COG2226@2|Bacteria,1MV7N@1224|Proteobacteria 1224|Proteobacteria Q Methyl-transferase - - - - - - - - - - - - Methyltransf_11,Methyltransf_25 k141_21399_1 218284.CCDN010000001_gene1302 7.35e-74 235.0 COG0477@1|root,COG2814@2|Bacteria,1VSW8@1239|Firmicutes,4HUQC@91061|Bacilli,1ZAS8@1386|Bacillus 91061|Bacilli EGP the major facilitator superfamily mdr GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - - - - - - - - - - MFS_1 k141_21400_1 441769.ABFU01000040_gene2990 8.93e-53 171.0 COG0835@1|root,COG0835@2|Bacteria,1V428@1239|Firmicutes,4HI77@91061|Bacilli,1ZFHY@1386|Bacillus 91061|Bacilli NT COG0835 Chemotaxis signal transduction protein - - - ko:K03408 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - CheW k141_36701_1 666686.B1NLA3E_14395 2.82e-76 248.0 COG0550@1|root,COG0550@2|Bacteria,1TPJD@1239|Firmicutes,4HAZV@91061|Bacilli,1ZBEG@1386|Bacillus 91061|Bacilli L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topB - 5.99.1.2 ko:K03169 - - - - ko00000,ko01000,ko03032 - - - Topoisom_bac,Toprim,Toprim_Crpt k141_36702_1 218284.CCDN010000001_gene1390 2.83e-95 289.0 COG1092@1|root,COG1092@2|Bacteria,1TRAJ@1239|Firmicutes,4HAA1@91061|Bacilli,1ZBVG@1386|Bacillus 91061|Bacilli J Methyltransferase ywbD - 2.1.1.191 ko:K06969 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_SAM k141_36703_1 1118153.MOY_02489 2.14e-09 57.4 COG4445@1|root,COG4445@2|Bacteria,1MVFE@1224|Proteobacteria,1RQ8Z@1236|Gammaproteobacteria,1XIJ2@135619|Oceanospirillales 135619|Oceanospirillales FJ Hydroxylase for synthesis of 2-methylthio-cis-ribozeatin in tRNA miaE - - ko:K06169 - - - - ko00000,ko01000,ko03016 - - - MiaE k141_36703_2 1219581.HMPREF1628_04400 4.06e-24 103.0 COG0515@1|root,COG0515@2|Bacteria,2GJ1J@201174|Actinobacteria,4D3B2@85005|Actinomycetales 201174|Actinobacteria KLT serine threonine protein kinase pknB GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 ko:K08884,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PASTA,Pkinase k141_30673_2 1042377.AFPJ01000032_gene2722 2.67e-110 325.0 COG1073@1|root,COG1073@2|Bacteria 2|Bacteria S thiolester hydrolase activity MA20_16590 - - ko:K06889,ko:K07397 - - - - ko00000 - - - Hydrolase_4,OsmC k141_30673_3 398720.MED217_03610 5.83e-11 58.9 2DNXG@1|root,32ZNF@2|Bacteria,4NV9Z@976|Bacteroidetes,1I563@117743|Flavobacteriia,2XJNA@283735|Leeuwenhoekiella 976|Bacteroidetes S Cysteine-rich CPXCG - - - - - - - - - - - - Cys_rich_CPXG k141_30673_4 1403313.AXBR01000003_gene3983 1.4e-68 223.0 COG1680@1|root,COG1680@2|Bacteria,1U828@1239|Firmicutes,4HA0Q@91061|Bacilli,1ZBJ0@1386|Bacillus 91061|Bacilli V Belongs to the UPF0214 family ybbE - 3.4.16.4 ko:K21469 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - Beta-lactamase k141_28444_2 218284.CCDN010000002_gene2089 1.92e-166 467.0 COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,4HBW0@91061|Bacilli,1ZCVE@1386|Bacillus 91061|Bacilli I Enoyl-CoA hydratase/isomerase paaF - 4.2.1.17 ko:K01692 ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212 M00032,M00087 R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093 RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 k141_31804_1 218284.CCDN010000001_gene1158 0.0 993.0 COG1205@1|root,COG1205@2|Bacteria,1TSPA@1239|Firmicutes,4H9T2@91061|Bacilli,1ZDM5@1386|Bacillus 91061|Bacilli L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster yprA GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - ko:K06877 - - - - ko00000 - - - DEAD,DUF1998,Helicase_C k141_31804_2 218284.CCDN010000001_gene1159 1.71e-36 135.0 COG3359@1|root,COG3359@2|Bacteria,1TQQU@1239|Firmicutes,4HDMU@91061|Bacilli,1ZAZQ@1386|Bacillus 91061|Bacilli L RNase_H superfamily yprB - - ko:K07502 - - - - ko00000 - - - RNase_H_2 k141_36705_1 1504981.KO116_3381 2.78e-97 292.0 COG2084@1|root,COG2084@2|Bacteria,1MUD0@1224|Proteobacteria,1RQXA@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Dehydrogenase ygbJ - 1.1.1.411 ko:K08319 - - - - ko00000,ko01000 - - - NAD_binding_11,NAD_binding_2 k141_30675_2 566466.NOR53_708 2.58e-98 296.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RPGB@1236|Gammaproteobacteria,1J8SN@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Acyl-CoA dehydrogenase, C-terminal domain - - 1.3.8.7 ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_28446_2 218284.CCDN010000001_gene1799 9.86e-91 268.0 COG2860@1|root,COG2860@2|Bacteria,1UH1K@1239|Firmicutes,4HDC7@91061|Bacilli,1ZBS1@1386|Bacillus 91061|Bacilli S membrane yvgT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - UPF0126 k141_36706_1 1294265.JCM21738_4811 3.44e-119 343.0 COG0569@1|root,COG0569@2|Bacteria,1TQ9H@1239|Firmicutes,4HBPH@91061|Bacilli,1ZC2N@1386|Bacillus 91061|Bacilli P COG0569 K transport systems, NAD-binding component - - - ko:K03499 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkA_C,TrkA_N k141_8203_1 1116375.VEJY3_00930 3.44e-09 57.0 COG0438@1|root,COG0438@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups - - - - - - - - - - - - Glyco_trans_1_4,Glycos_transf_1 k141_8203_2 1116375.VEJY3_00935 2.08e-99 299.0 COG1216@1|root,COG1216@2|Bacteria,1QRMS@1224|Proteobacteria,1RUPE@1236|Gammaproteobacteria,1Y1A6@135623|Vibrionales 135623|Vibrionales H Glycosyl transferase, family 2 - - - - - - - - - - - - - k141_8203_3 1116375.VEJY3_00940 6.97e-229 638.0 COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,1RNBR@1236|Gammaproteobacteria,1XTJM@135623|Vibrionales 135623|Vibrionales M 3-deoxy-D-manno-octulosonic-acid transferase kdtA - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 ko:K02527 ko00540,ko01100,map00540,map01100 M00060,M00080 R04658,R05074,R09763 RC00009,RC00077,RC00247 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT30 - Glycos_transf_1,Glycos_transf_N k141_8203_4 1116375.VEJY3_00945 3.69e-244 672.0 COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,1RMBF@1236|Gammaproteobacteria,1XTBX@135623|Vibrionales 135623|Vibrionales M ADP-heptose--LPS heptosyltransferase II rfaF - - ko:K02843 ko00540,ko01100,map00540,map01100 M00080 - - ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT9 - Glyco_transf_9 k141_30677_1 28532.XP_010536586.1 1.63e-27 115.0 COG0542@1|root,KOG1051@2759|Eukaryota,37RK8@33090|Viridiplantae,3GD7P@35493|Streptophyta,3HVZI@3699|Brassicales 35493|Streptophyta O Belongs to the ClpA ClpB family - GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006508,GO:0006605,GO:0006807,GO:0006810,GO:0006886,GO:0006996,GO:0008104,GO:0008150,GO:0008152,GO:0008233,GO:0009507,GO:0009526,GO:0009528,GO:0009532,GO:0009534,GO:0009535,GO:0009536,GO:0009570,GO:0009579,GO:0009657,GO:0009658,GO:0009706,GO:0009719,GO:0009725,GO:0009735,GO:0009889,GO:0009941,GO:0009987,GO:0010033,GO:0010380,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017038,GO:0017111,GO:0019222,GO:0019538,GO:0019866,GO:0030312,GO:0031090,GO:0031323,GO:0031326,GO:0031897,GO:0031967,GO:0031969,GO:0031975,GO:0031976,GO:0031984,GO:0032991,GO:0033036,GO:0033365,GO:0034357,GO:0034613,GO:0042170,GO:0042221,GO:0042623,GO:0042651,GO:0042886,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044422,GO:0044424,GO:0044425,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0045036,GO:0045037,GO:0045184,GO:0046907,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051179,GO:0051193,GO:0051234,GO:0051641,GO:0051649,GO:0055035,GO:0055085,GO:0065002,GO:0065007,GO:0070011,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072596,GO:0072598,GO:0090056,GO:0098796,GO:0140096,GO:1901401,GO:1901463,GO:1901564 - ko:K03696 ko01100,map01100 - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N,UVR k141_36707_1 1453501.JELR01000001_gene2649 7.36e-100 300.0 COG2207@1|root,COG2207@2|Bacteria,1R5D8@1224|Proteobacteria,1RYEI@1236|Gammaproteobacteria,46B2H@72275|Alteromonadaceae 1236|Gammaproteobacteria K Arabinose-binding domain of AraC transcription regulator, N-term - - - - - - - - - - - - Arabinose_bd,HTH_18 k141_30678_1 218284.CCDN010000008_gene4148 8e-85 256.0 COG0300@1|root,COG0300@2|Bacteria,1UG37@1239|Firmicutes,4HC7Y@91061|Bacilli,1ZDQ3@1386|Bacillus 91061|Bacilli S Belongs to the short-chain dehydrogenases reductases (SDR) family fabG - 1.1.1.100 ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short k141_28449_1 1285586.H131_02403 5.73e-10 64.7 COG1413@1|root,COG1413@2|Bacteria,1V32S@1239|Firmicutes,4HMNP@91061|Bacilli,3IXDG@400634|Lysinibacillus 91061|Bacilli C COG1413 FOG HEAT repeat - - - - - - - - - - - - HEAT,HEAT_2 k141_31808_1 1265502.KB905932_gene1828 6.8e-53 178.0 COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,2VJ9D@28216|Betaproteobacteria,4AADT@80864|Comamonadaceae 28216|Betaproteobacteria U Belongs to the peptidase S26 family lepB - 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24,Peptidase_S26 k141_15351_1 1279017.AQYJ01000027_gene1829 6.4e-316 889.0 COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,1MX3A@1224|Proteobacteria,1RMQZ@1236|Gammaproteobacteria,4641W@72275|Alteromonadaceae 1236|Gammaproteobacteria QU COG0823 Periplasmic component of the Tol biopolymer transport system - - - - - - - - - - - - Amidohydro_1,PD40 k141_15351_2 236097.ADG881_3173 1.66e-105 317.0 COG3965@1|root,COG3965@2|Bacteria,1MXVG@1224|Proteobacteria,1RSB7@1236|Gammaproteobacteria,1XPNA@135619|Oceanospirillales 135619|Oceanospirillales P Cation efflux family - - - - - - - - - - - - Cation_efflux k141_15351_3 1237149.C900_00448 9.31e-52 177.0 COG2116@1|root,COG2116@2|Bacteria,4NFNU@976|Bacteroidetes,47Q8C@768503|Cytophagia 976|Bacteroidetes P Formate/nitrite transporter - - - ko:K21990,ko:K21993 - - - - ko00000,ko02000 1.A.16.2,1.A.16.4 - - Form_Nir_trans k141_15351_4 1453501.JELR01000002_gene1134 9.56e-147 424.0 COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,1RRA1@1236|Gammaproteobacteria,4641H@72275|Alteromonadaceae 1236|Gammaproteobacteria S esterase of the alpha-beta hydrolase superfamily rssA GO:0003674,GO:0003824,GO:0016787 - ko:K07001 - - - - ko00000 - - - Patatin k141_15351_5 1236541.BALL01000026_gene3027 1.17e-20 90.9 2EXJW@1|root,33QVY@2|Bacteria,1QSMJ@1224|Proteobacteria,1SK5H@1236|Gammaproteobacteria,2QA2U@267890|Shewanellaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_8205_1 218284.CCDN010000002_gene2253 4.39e-117 340.0 COG3568@1|root,COG3568@2|Bacteria,1TQZG@1239|Firmicutes,4HGS5@91061|Bacilli,1ZQ0K@1386|Bacillus 91061|Bacilli L Endonuclease/Exonuclease/phosphatase family rgfB - 3.1.3.90 ko:K06896 ko00500,map00500 - R10486 RC00017 ko00000,ko00001,ko01000 - - - Exo_endo_phos k141_36712_1 1453501.JELR01000002_gene65 1.64e-18 82.8 COG0720@1|root,COG0720@2|Bacteria,1MXVT@1224|Proteobacteria,1RN6H@1236|Gammaproteobacteria,464QP@72275|Alteromonadaceae 1236|Gammaproteobacteria H COG0720 6-pyruvoyl-tetrahydropterin synthase SO2179 - 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 - - - PTPS k141_36712_2 1042377.AFPJ01000025_gene602 2.73e-55 180.0 COG1385@1|root,COG1385@2|Bacteria,1MZBG@1224|Proteobacteria,1S0HM@1236|Gammaproteobacteria,464CI@72275|Alteromonadaceae 1236|Gammaproteobacteria J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit - - - - - - - - - - - - Methyltrans_RNA k141_30681_1 218284.CCDN010000005_gene3465 3.99e-57 177.0 2EPRF@1|root,33HBX@2|Bacteria,1VP6R@1239|Firmicutes,4HRWK@91061|Bacilli,1ZIF1@1386|Bacillus 91061|Bacilli S Required for proper spore morphogenesis. Important for spore germination ywcE GO:0008150,GO:0009847,GO:0032502 - - - - - - - - - - YwcE k141_36713_1 1120950.KB892708_gene4403 1.14e-05 52.0 COG1668@1|root,COG1668@2|Bacteria,2GQE9@201174|Actinobacteria 201174|Actinobacteria CP ABC-2 family transporter protein - - - - - - - - - - - - ABC2_membrane_2 k141_30682_1 1157490.EL26_18555 1.8e-76 243.0 COG0397@1|root,COG0397@2|Bacteria,1TQXD@1239|Firmicutes,4HBKH@91061|Bacilli 91061|Bacilli S Belongs to the UPF0061 (SELO) family M1-1044 - - - - - - - - - - - UPF0061 k141_36714_1 218284.CCDN010000011_gene4422 5.82e-100 300.0 COG1721@1|root,COG1721@2|Bacteria,1TUWF@1239|Firmicutes,4HDRE@91061|Bacilli,1ZCAS@1386|Bacillus 91061|Bacilli S conserved protein (some members contain a von Willebrand factor type A (vWA) domain) yeaD - - - - - - - - - - - DUF58 k141_8208_1 1450694.BTS2_1305 9.99e-15 70.5 COG1396@1|root,COG1396@2|Bacteria,1UV5V@1239|Firmicutes,4IMAW@91061|Bacilli,1ZJP6@1386|Bacillus 91061|Bacilli K Cro/C1-type HTH DNA-binding domain - - - ko:K19417 - - - - ko00000,ko03000 - - - HTH_3,SinI k141_28454_1 1042377.AFPJ01000007_gene1872 1.35e-85 260.0 arCOG10317@1|root,2Z7VW@2|Bacteria,1RGUS@1224|Proteobacteria,1S5VW@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_6025_1 218284.CCDN010000002_gene2854 1.55e-62 194.0 2AQ3P@1|root,31F8Y@2|Bacteria,1V8J9@1239|Firmicutes,4HJHH@91061|Bacilli,1ZGY3@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - Polyketide_cyc2 k141_119_1 536232.CLM_1632 8.27e-44 152.0 2E1QR@1|root,32X0X@2|Bacteria,1VBXN@1239|Firmicutes,25Q9D@186801|Clostridia,36U1P@31979|Clostridiaceae 186801|Clostridia S ERF superfamily - - - - - - - - - - - - ERF k141_119_6 320483.AMF_127 1.42e-07 53.1 COG1351@1|root,COG1351@2|Bacteria,1MWY8@1224|Proteobacteria,2TTER@28211|Alphaproteobacteria,47F1N@766|Rickettsiales 766|Rickettsiales F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant thyX - 2.1.1.148 ko:K03465 ko00240,ko00670,ko01100,map00240,map00670,map01100 - R06613 RC00022,RC00332 ko00000,ko00001,ko01000 - - - Thy1 k141_17956_2 665959.HMPREF1013_01576 9.18e-32 126.0 COG2905@1|root,COG2905@2|Bacteria,1TQFI@1239|Firmicutes,4HCIW@91061|Bacilli,1ZCEI@1386|Bacillus 91061|Bacilli T Putative nucleotidyltransferase substrate binding domain - - - ko:K07182 - - - - ko00000 - - - CBS,DUF294,DUF294_C,cNMP_binding k141_29797_1 1116375.VEJY3_03385 1.7e-258 709.0 COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,1RMBI@1236|Gammaproteobacteria,1XTPY@135623|Vibrionales 135623|Vibrionales J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner ychF - - ko:K06942 - - - - ko00000,ko03009 - - - MMR_HSR1,YchF-GTPase_C k141_29797_2 1116375.VEJY3_03390 7.32e-140 395.0 COG0193@1|root,COG0193@2|Bacteria,1MX1P@1224|Proteobacteria,1RPK3@1236|Gammaproteobacteria,1XT46@135623|Vibrionales 135623|Vibrionales J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis pth GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 ko:K01056 - - - - ko00000,ko01000,ko03012 - - - Pept_tRNA_hydro k141_29797_3 1116375.VEJY3_03395 3.47e-215 595.0 COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,1RMUC@1236|Gammaproteobacteria,1XSZQ@135623|Vibrionales 135623|Vibrionales F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) prs GO:0003674,GO:0003824,GO:0004749,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - Pribosyl_synth,Pribosyltran_N k141_29797_4 674977.VMC_10070 2.21e-166 468.0 COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,1RP23@1236|Gammaproteobacteria,1XUCF@135623|Vibrionales 135623|Vibrionales F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol ispE GO:0003674,GO:0003824,GO:0006629,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050515,GO:0071704,GO:1901576 2.7.1.148 ko:K00919 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05634 RC00002,RC01439 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N k141_26264_1 1453501.JELR01000002_gene81 1.17e-97 308.0 COG3291@1|root,COG5297@1|root,COG3291@2|Bacteria,COG5297@2|Bacteria,1QZ9W@1224|Proteobacteria,1RPFR@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Glycosyl hydrolase family 9 - - 3.2.1.4 ko:K01179 ko00500,ko01100,map00500,map01100 - R06200,R11307,R11308 - ko00000,ko00001,ko01000 - GH5,GH9 - CBM_2,CBM_3,CBM_5_12_2,Glyco_hydro_9 k141_36908_2 1279017.AQYJ01000028_gene2086 6.95e-207 578.0 COG2831@1|root,COG2831@2|Bacteria,1QW38@1224|Proteobacteria,1T2R4@1236|Gammaproteobacteria,464F6@72275|Alteromonadaceae 1236|Gammaproteobacteria U Protein of unknown function (DUF3570) - - - - - - - - - - - - DUF3570 k141_36908_4 296587.XP_002509297.1 6.13e-41 146.0 COG0693@1|root,KOG2764@2759|Eukaryota,37K07@33090|Viridiplantae 33090|Viridiplantae V Protein DJ-1 homolog - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005773,GO:0005774,GO:0005829,GO:0005886,GO:0005911,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009438,GO:0009506,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019172,GO:0019249,GO:0019752,GO:0030054,GO:0031090,GO:0032787,GO:0042180,GO:0042182,GO:0042221,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0046185,GO:0046394,GO:0046686,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0051596,GO:0055044,GO:0061727,GO:0065007,GO:0071704,GO:0071944,GO:0072330,GO:0080134,GO:0080135,GO:0098588,GO:0098805,GO:1900407,GO:1900409,GO:1901575,GO:1901576,GO:1901615,GO:1901617,GO:1902882,GO:1902884 3.5.1.124 ko:K03152 - - - - ko00000,ko01000,ko01002 - - - DJ-1_PfpI k141_36908_5 1121373.KB903631_gene624 4.87e-90 274.0 COG2197@1|root,COG2197@2|Bacteria,4NQZ6@976|Bacteroidetes,47XFK@768503|Cytophagia 976|Bacteroidetes KT helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE,PAS_3 k141_36908_6 1333856.L686_13295 5.16e-58 184.0 COG5579@1|root,COG5579@2|Bacteria,1RGXV@1224|Proteobacteria,1S6K5@1236|Gammaproteobacteria,1Z335@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria S Protein of unknown function (DUF1810) - - - - - - - - - - - - DUF1810 k141_36908_7 1042377.AFPJ01000008_gene1956 0.0 947.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MV8W@1224|Proteobacteria,1RQEQ@1236|Gammaproteobacteria,463XU@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec k141_27400_1 1132442.KB889752_gene1027 4.99e-08 50.1 2EG09@1|root,339SB@2|Bacteria,1VG42@1239|Firmicutes,4HRC7@91061|Bacilli,1ZISG@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_16711_1 1042377.AFPJ01000012_gene1341 1.13e-148 429.0 COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,1RN5S@1236|Gammaproteobacteria,46440@72275|Alteromonadaceae 1236|Gammaproteobacteria J Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 mnmE GO:0000166,GO:0001510,GO:0001882,GO:0001883,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006457,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009268,GO:0009451,GO:0009628,GO:0009636,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0030488,GO:0030955,GO:0031420,GO:0032259,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0061077,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 - ko:K03650 - - R08701 RC00053,RC00209,RC00870 ko00000,ko01000,ko03016 - - - MMR_HSR1,MnmE_helical,TrmE_N k141_34572_1 1279017.AQYJ01000026_gene31 3.44e-104 331.0 COG4913@1|root,COG4913@2|Bacteria,1N16Z@1224|Proteobacteria,1RYVF@1236|Gammaproteobacteria,465ZJ@72275|Alteromonadaceae 1236|Gammaproteobacteria S Putative exonuclease SbcCD, C subunit - - - - - - - - - - - - AAA_29,SbcCD_C k141_8450_1 218284.CCDN010000002_gene2002 1.01e-154 447.0 COG2225@1|root,COG2225@2|Bacteria,1TPE8@1239|Firmicutes,4H9ST@91061|Bacilli,1ZBY7@1386|Bacillus 91061|Bacilli C Belongs to the malate synthase family aceB - 2.3.3.9 ko:K01638 ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200 M00012 R00472 RC00004,RC00308,RC02747 ko00000,ko00001,ko00002,ko01000 - - - Malate_synthase k141_6066_1 1095770.CAHE01000060_gene1534 0.00042 48.1 COG1484@1|root,COG1484@2|Bacteria,1TPZX@1239|Firmicutes,248F0@186801|Clostridia,22GPA@1570339|Peptoniphilaceae 186801|Clostridia L IstB-like ATP binding protein - - - ko:K02315 - - - - ko00000,ko03032 - - - IstB_IS21 k141_15568_1 218284.CCDN010000001_gene1824 1.66e-153 452.0 COG0550@1|root,COG0551@1|root,COG0550@2|Bacteria,COG0551@2|Bacteria,1TPJD@1239|Firmicutes,4HAZV@91061|Bacilli,1ZBEG@1386|Bacillus 91061|Bacilli L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topB - 5.99.1.2 ko:K03169 - - - - ko00000,ko01000,ko03032 - - - Topoisom_bac,Toprim k141_10766_2 1347086.CCBA010000030_gene62 1.52e-78 241.0 COG1161@1|root,COG1161@2|Bacteria,1TQGK@1239|Firmicutes,4HA4D@91061|Bacilli,1ZB63@1386|Bacillus 91061|Bacilli S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity rbgA GO:0003674,GO:0003824,GO:0003924,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022613,GO:0042254,GO:0044085,GO:0071840 - ko:K14540 - - - - ko00000,ko03009 - - - MMR_HSR1 k141_34573_1 218284.CCDN010000008_gene4169 6.33e-38 139.0 COG1866@1|root,COG1866@2|Bacteria,1TPQV@1239|Firmicutes,4HAKG@91061|Bacilli,1ZCVN@1386|Bacillus 91061|Bacilli C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA pckA GO:0000166,GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0017076,GO:0019318,GO:0019319,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576 4.1.1.49 ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 M00003,M00170 R00341 RC00002,RC02741 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS09060,iYO844.BSU30560 PEPCK_ATP k141_13201_1 1294265.JCM21738_5505 2.7e-95 286.0 COG3861@1|root,COG3861@2|Bacteria,1V9A1@1239|Firmicutes,4HISC@91061|Bacilli,1ZE4F@1386|Bacillus 91061|Bacilli S protein conserved in bacteria ysnF - - - - - - - - - - - DUF2382,YflT k141_26266_1 1453501.JELR01000002_gene1287 5.57e-86 257.0 COG0625@1|root,COG0625@2|Bacteria,1RDBD@1224|Proteobacteria 1224|Proteobacteria O Glutathione S-transferase - - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_N_3 k141_4860_1 1042377.AFPJ01000004_gene333 1.11e-38 148.0 COG1361@1|root,COG3210@1|root,COG1361@2|Bacteria,COG3210@2|Bacteria,1QUXB@1224|Proteobacteria,1T5IP@1236|Gammaproteobacteria 1236|Gammaproteobacteria MU Domain of unknown function (DUF4347) - - - - - - - - - - - - DUF11,DUF4347 k141_29798_1 665959.HMPREF1013_05681 3.52e-41 143.0 COG1595@1|root,COG1595@2|Bacteria,1V9ZH@1239|Firmicutes,4IQ4H@91061|Bacilli,1ZGTX@1386|Bacillus 91061|Bacilli K Sigma-70, region 4 - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_25030_1 997296.PB1_03600 4.36e-71 220.0 COG1670@1|root,COG1670@2|Bacteria,1V51P@1239|Firmicutes,4HI8D@91061|Bacilli,1ZQUX@1386|Bacillus 91061|Bacilli J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins - - - ko:K03817 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 k141_8451_1 1462527.CCDM010000004_gene3469 4.39e-46 158.0 COG3173@1|root,COG3173@2|Bacteria,1UZ6J@1239|Firmicutes,4HEYZ@91061|Bacilli 91061|Bacilli S Phosphotransferase enzyme family - - - - - - - - - - - - APH k141_26267_1 240302.BN982_02496 1.51e-100 305.0 COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,4H9VK@91061|Bacilli,3ND3W@45667|Halobacillus 91061|Bacilli G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system rbsA GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0006810,GO:0008144,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015146,GO:0015399,GO:0015405,GO:0015407,GO:0015591,GO:0015608,GO:0015611,GO:0015749,GO:0015750,GO:0015752,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034219,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043211,GO:0043492,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0097159,GO:0097367,GO:1901265,GO:1901363 3.6.3.17 ko:K10441 ko02010,map02010 M00212 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - ABC_tran k141_17959_1 997296.PB1_07912 2.41e-121 361.0 COG0018@1|root,COG0018@2|Bacteria,1TPEZ@1239|Firmicutes,4HAR3@91061|Bacilli,1ZBP1@1386|Bacillus 91061|Bacilli J Arginyl-tRNA synthetase argS GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d k141_122_1 1294265.JCM21738_4842 2.9e-48 166.0 COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HA52@91061|Bacilli,1ZCQI@1386|Bacillus 91061|Bacilli T Histidine kinase vicK - 2.7.13.3 ko:K07652 ko02020,map02020 M00459 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,PAS,PAS_9 k141_122_2 1294265.JCM21738_4843 2.12e-50 171.0 COG4863@1|root,COG4863@2|Bacteria,1UV48@1239|Firmicutes,4HF30@91061|Bacilli,1ZD30@1386|Bacillus 91061|Bacilli S protein conserved in bacteria yycH - - - - - - - - - - - YycH k141_13202_2 218284.CCDN010000004_gene3153 2.8e-30 118.0 COG0189@1|root,COG0189@2|Bacteria,1V1EV@1239|Firmicutes,4HFNI@91061|Bacilli,1ZBM5@1386|Bacillus 91061|Bacilli HJ YheC/D like ATP-grasp - - - - - - - - - - - - ATPgrasp_YheCD k141_22690_1 1042377.AFPJ01000035_gene2641 1.22e-222 639.0 COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,1SC2U@1236|Gammaproteobacteria,46A5A@72275|Alteromonadaceae 1236|Gammaproteobacteria T diguanylate cyclase ycdT GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0032879,GO:0042710,GO:0044010,GO:0044464,GO:0044764,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051270,GO:0051271,GO:0051704,GO:0052621,GO:0065007,GO:0071944,GO:0090605,GO:0090609 - - - - - - - - - - 7TMR-DISMED2,7TMR-DISM_7TM,GGDEF,MASE4 k141_22690_2 1125973.JNLC01000015_gene3257 9.74e-23 93.6 COG0346@1|root,COG0346@2|Bacteria,1RH4D@1224|Proteobacteria,2U7GX@28211|Alphaproteobacteria,3JYQ4@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - Glyoxalase k141_34575_1 1453501.JELR01000002_gene1020 1.8e-150 437.0 COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,1RMT7@1236|Gammaproteobacteria,4640X@72275|Alteromonadaceae 1236|Gammaproteobacteria S Bacterial protein of unknown function (DUF885) - - - - - - - - - - - - DUF885 k141_29799_1 218284.CCDN010000007_gene3887 1.31e-36 135.0 COG1502@1|root,COG1502@2|Bacteria,1TQ2Q@1239|Firmicutes,4H9SX@91061|Bacilli,1ZBA2@1386|Bacillus 91061|Bacilli I PLD-like domain cls2 - - - - - - - - - - - PLDc_2 k141_28652_2 1234664.AMRO01000077_gene3477 1.31e-84 262.0 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli,1WG2K@129337|Geobacillus 91061|Bacilli C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively iolA - 1.2.1.18,1.2.1.27 ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 M00013 R00705,R00706,R00922,R00935 RC00004,RC02723,RC02817 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_17960_2 1423321.AS29_11215 9.33e-77 241.0 COG1653@1|root,COG1653@2|Bacteria,1TQ0V@1239|Firmicutes,4HA7Z@91061|Bacilli,1ZF6A@1386|Bacillus 91061|Bacilli G ABC transporter substrate-binding protein - - - - - - - - - - - - SBP_bac_1,SBP_bac_8 k141_14374_3 1121943.KB899989_gene3291 5.9e-77 238.0 COG0744@1|root,COG0744@2|Bacteria,1RDAQ@1224|Proteobacteria,1RMGB@1236|Gammaproteobacteria,1XJJD@135619|Oceanospirillales 135619|Oceanospirillales M Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors mtgA - 2.4.1.129 ko:K03814 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly k141_14374_4 1121015.N789_06965 1.35e-18 82.4 COG1748@1|root,COG1748@2|Bacteria,1P35E@1224|Proteobacteria,1SH6U@1236|Gammaproteobacteria,1X6QQ@135614|Xanthomonadales 135614|Xanthomonadales E Domain of unknown function (DUF4166) - - - - - - - - - - - - DUF4166 k141_21523_2 1453501.JELR01000002_gene935 2.65e-207 579.0 COG1162@1|root,COG1162@2|Bacteria,1MUEF@1224|Proteobacteria,1RMMB@1236|Gammaproteobacteria,464F3@72275|Alteromonadaceae 1236|Gammaproteobacteria S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit rsgA GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0022613,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0036094,GO:0042254,GO:0042274,GO:0043167,GO:0043168,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 - R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 - - iAF1260.b4161,iBWG_1329.BWG_3876,iECDH10B_1368.ECDH10B_4356,iECDH1ME8569_1439.ECDH1ME8569_4021,iEKO11_1354.EKO11_4148,iEcDH1_1363.EcDH1_3829,iEcolC_1368.EcolC_3849,iJO1366.b4161,iUMNK88_1353.UMNK88_5099,iY75_1357.Y75_RS21675 RsgA_GTPase k141_21523_3 1279017.AQYJ01000027_gene1576 3.35e-157 444.0 COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,1RSQ3@1236|Gammaproteobacteria,465W6@72275|Alteromonadaceae 1236|Gammaproteobacteria P Rhodanese Homology Domain rhdA - 2.8.1.1,2.8.1.2 ko:K01011 ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122 - R01931,R03105,R03106 RC00214 ko00000,ko00001,ko01000 - - - Rhodanese k141_21523_4 1279017.AQYJ01000027_gene1577 3.08e-160 454.0 COG0688@1|root,COG0688@2|Bacteria,1MVT4@1224|Proteobacteria,1RN1U@1236|Gammaproteobacteria,4656J@72275|Alteromonadaceae 1236|Gammaproteobacteria I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) psd - 4.1.1.65 ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 M00093 R02055 RC00299 ko00000,ko00001,ko00002,ko01000 - - - PS_Dcarbxylase k141_21523_5 1453501.JELR01000002_gene938 5.25e-88 272.0 COG0477@1|root,COG2814@2|Bacteria,1QUD1@1224|Proteobacteria,1RQ0V@1236|Gammaproteobacteria,463Z1@72275|Alteromonadaceae 1236|Gammaproteobacteria EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 k141_16714_1 218284.CCDN010000001_gene1391 7e-28 108.0 COG4814@1|root,COG4814@2|Bacteria,1V910@1239|Firmicutes,4HF90@91061|Bacilli,1ZHBI@1386|Bacillus 91061|Bacilli S Alpha/beta hydrolase of unknown function (DUF915) - - - - - - - - - - - - DUF915 k141_16714_2 218284.CCDN010000001_gene1391 3.4e-11 61.2 COG4814@1|root,COG4814@2|Bacteria,1V910@1239|Firmicutes,4HF90@91061|Bacilli,1ZHBI@1386|Bacillus 91061|Bacilli S Alpha/beta hydrolase of unknown function (DUF915) - - - - - - - - - - - - DUF915 k141_13203_1 1385514.N782_04900 1.61e-13 72.4 COG0546@1|root,COG0546@2|Bacteria,1UI4N@1239|Firmicutes,4ISD8@91061|Bacilli,2YBX8@289201|Pontibacillus 91061|Bacilli S haloacid dehalogenase-like hydrolase - - - ko:K07025 - - - - ko00000 - - - HAD_2 k141_13203_2 686340.Metal_0908 6.55e-44 145.0 COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,1S3QE@1236|Gammaproteobacteria,1XFE1@135618|Methylococcales 135618|Methylococcales FG Scavenger mRNA decapping enzyme C-term binding - - - ko:K02503 - - - - ko00000,ko04147 - - - HIT k141_13203_3 243233.MCA2992 7.29e-22 92.0 COG1610@1|root,COG1610@2|Bacteria,1RGZS@1224|Proteobacteria,1S61A@1236|Gammaproteobacteria,1XF5X@135618|Methylococcales 135618|Methylococcales S Yqey-like protein - - - ko:K09117 - - - - ko00000 - - - YqeY k141_17961_1 218284.CCDN010000002_gene2798 1.24e-96 313.0 COG0308@1|root,COG0577@1|root,COG4591@1|root,COG0308@2|Bacteria,COG0577@2|Bacteria,COG4591@2|Bacteria,1TSZH@1239|Firmicutes,4HCKC@91061|Bacilli 91061|Bacilli MV FtsX-like permease family - - - - - - - - - - - - FtsX k141_29800_1 935837.JAEK01000036_gene2960 3.22e-45 157.0 COG4175@1|root,COG4175@2|Bacteria,1UHNE@1239|Firmicutes,4HA9P@91061|Bacilli,1ZS1P@1386|Bacillus 91061|Bacilli E glycine betaine opuAA - 3.6.3.32 ko:K02000 ko02010,map02010 M00208 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.12 - - ABC_tran,CBS k141_22691_1 157783.LK03_02225 0.000233 48.5 COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,1RMJ1@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Belongs to the 'phage' integrase family intB - - - - - - - - - - - Arm-DNA-bind_3,Phage_integrase k141_15571_1 986075.CathTA2_1719 3.76e-135 394.0 COG0626@1|root,COG0626@2|Bacteria,1TPC7@1239|Firmicutes,4HAFQ@91061|Bacilli 91061|Bacilli E cystathionine metB GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0016740,GO:0016765,GO:0016829,GO:0016846 2.5.1.48 ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017 R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946 RC00020,RC00056,RC00069,RC00420,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000 - - - Cys_Met_Meta_PP k141_14375_1 218284.CCDN010000001_gene1967 9.62e-139 398.0 COG0673@1|root,COG0673@2|Bacteria,1TQ72@1239|Firmicutes,4HAGN@91061|Bacilli,1ZCVI@1386|Bacillus 91061|Bacilli S Oxidoreductase family, C-terminal alpha/beta domain - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C k141_9595_1 218284.CCDN010000001_gene1219 1.77e-153 442.0 COG1509@1|root,COG1509@2|Bacteria,1TQQZ@1239|Firmicutes,4HE2P@91061|Bacilli,1ZBET@1386|Bacillus 91061|Bacilli E lysine 2,3-aminomutase kamA - 5.4.3.2 ko:K01843 ko00310,map00310 - R00461 RC00303 ko00000,ko00001,ko01000 - - - Fer4_12,Fer4_14,LAM_C,Radical_SAM k141_9595_2 218284.CCDN010000001_gene1220 7.21e-35 121.0 2FGYP@1|root,348TV@2|Bacteria,1VZPM@1239|Firmicutes,4HYBM@91061|Bacilli,1ZHW2@1386|Bacillus 91061|Bacilli S YokU-like protein, putative antitoxin - - - - - - - - - - - - YokU k141_9595_3 1307436.PBF_17704 9.17e-33 114.0 COG4479@1|root,COG4479@2|Bacteria,1VFI4@1239|Firmicutes,4HR7P@91061|Bacilli,1ZJ7C@1386|Bacillus 91061|Bacilli S Belongs to the UPF0346 family yozE - - - - - - - - - - - YozE_SAM_like k141_150_1 218284.CCDN010000005_gene3239 3.32e-94 278.0 2E4ZB@1|root,32ZT1@2|Bacteria,1VHAC@1239|Firmicutes,4HQBP@91061|Bacilli,1ZD5D@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2777) yisN - - - - - - - - - - - DUF2777 k141_150_2 545276.KB898726_gene984 5.83e-06 48.9 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,PAS_3,PAS_4,PAS_9,Reg_prop k141_10781_2 1279017.AQYJ01000024_gene1187 4.34e-59 186.0 COG2062@1|root,COG2062@2|Bacteria,1RG7G@1224|Proteobacteria,1RTH3@1236|Gammaproteobacteria,468NQ@72275|Alteromonadaceae 1236|Gammaproteobacteria T phosphohistidine phosphatase, SixA - - - ko:K08296 - - - - ko00000,ko01000 - - - His_Phos_1 k141_1242_1 218284.CCDN010000001_gene760 6.52e-201 571.0 COG0358@1|root,COG0358@2|Bacteria,1TQ0X@1239|Firmicutes,4HAG2@91061|Bacilli,1ZC16@1386|Bacillus 91061|Bacilli L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG - - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2 k141_1242_2 218284.CCDN010000001_gene759 3.85e-55 174.0 COG1671@1|root,COG1671@2|Bacteria,1V9Z0@1239|Firmicutes,4HM1G@91061|Bacilli,1ZFK7@1386|Bacillus 91061|Bacilli S Belongs to the UPF0178 family yqxD - - ko:K09768 - - - - ko00000 - - - DUF188 k141_13224_1 1122128.AUEE01000007_gene1666 8.07e-109 325.0 COG1783@1|root,COG1783@2|Bacteria,1TRQP@1239|Firmicutes,4HDMY@91061|Bacilli,4GZBA@90964|Staphylococcaceae 91061|Bacilli S Terminase RNAseH like domain - - - ko:K06909 - - - - ko00000 - - - Terminase_3,Terminase_3C k141_21550_1 1196031.ALEG01000072_gene917 6.73e-87 270.0 COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,4HAM7@91061|Bacilli,1ZBG8@1386|Bacillus 91061|Bacilli E COG0747 ABC-type dipeptide transport system, periplasmic component - - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 k141_6077_1 1415630.U771_07040 1.53e-64 208.0 COG3948@1|root,COG3948@2|Bacteria,1RIMI@1224|Proteobacteria,1S8MK@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Baseplate J protein - - - - - - - - - - - - Baseplate_J k141_6077_2 1283337.B0ZSF8_BPHA1 5.38e-20 82.8 4QAZ7@10239|Viruses,4R0NI@35237|dsDNA viruses no RNA stage,4QTYE@28883|Caudovirales,4QHXC@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k141_19124_1 1279017.AQYJ01000029_gene3588 3.89e-70 220.0 COG3496@1|root,COG3496@2|Bacteria,1RC56@1224|Proteobacteria,1RRT8@1236|Gammaproteobacteria,465C9@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF1365) - - - ko:K09701 - - - - ko00000 - - - DUF1365 k141_19124_3 1279017.AQYJ01000029_gene3590 1.99e-55 179.0 2CH72@1|root,31GTD@2|Bacteria,1QEGI@1224|Proteobacteria,1TB5S@1236|Gammaproteobacteria,4697T@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF2878) - - - - - - - - - - - - DUF2878 k141_3697_1 218284.CCDN010000005_gene3495 5.12e-12 65.1 COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,1TPKU@1239|Firmicutes,4H9KR@91061|Bacilli,1ZAVB@1386|Bacillus 91061|Bacilli GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type) fruA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563 2.7.1.202 ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1 - - PTS_EIIA_2,PTS_EIIC,PTS_IIB k141_3697_2 218284.CCDN010000005_gene3494 2.72e-80 246.0 COG1105@1|root,COG1105@2|Bacteria,1TQ36@1239|Firmicutes,4HANU@91061|Bacilli,1ZB76@1386|Bacillus 91061|Bacilli G Belongs to the carbohydrate kinase PfkB family pfkB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046835,GO:0071704 2.7.1.56 ko:K00882 ko00051,map00051 - R02071 RC00002,RC00017 ko00000,ko00001,ko01000 - - iYO844.BSU14390 PfkB k141_1243_1 1279017.AQYJ01000024_gene975 1.39e-99 306.0 COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,1RM8M@1236|Gammaproteobacteria,46473@72275|Alteromonadaceae 1236|Gammaproteobacteria M Transfers the fatty acyl group on membrane lipoproteins lnt GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016021,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031224,GO:0031226,GO:0034645,GO:0036211,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576 - ko:K03820 - - - - ko00000,ko01000 - GT2 iEcSMS35_1347.EcSMS35_0678,iSbBS512_1146.SbBS512_E0590 CN_hydrolase k141_1243_2 1453501.JELR01000001_gene2969 1.87e-179 503.0 COG4535@1|root,COG4535@2|Bacteria,1QTU8@1224|Proteobacteria,1RMKX@1236|Gammaproteobacteria,4658M@72275|Alteromonadaceae 1236|Gammaproteobacteria P Mg2 and Co2 transporter CorC corC GO:0001897,GO:0001906,GO:0001907,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009405,GO:0009987,GO:0016020,GO:0019835,GO:0019836,GO:0031640,GO:0035821,GO:0044003,GO:0044004,GO:0044179,GO:0044364,GO:0044403,GO:0044419,GO:0044464,GO:0044764,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0071944 - ko:K06189 - - - - ko00000,ko02000 9.A.40.1.2 - - CBS,CorC_HlyC k141_1243_3 1453501.JELR01000001_gene2968 7.47e-73 223.0 COG0319@1|root,COG0319@2|Bacteria,1MZ67@1224|Proteobacteria,1S6BS@1236|Gammaproteobacteria,467I5@72275|Alteromonadaceae 1236|Gammaproteobacteria J Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ybeY GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - ko:K07042 - - - - ko00000,ko03009 - - - UPF0054 k141_32175_1 1042377.AFPJ01000036_gene1150 1.15e-69 224.0 COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,1RPAB@1236|Gammaproteobacteria,469E2@72275|Alteromonadaceae 1236|Gammaproteobacteria C Glycolate oxidase iron-sulfur subunit glcF - - ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001 - - - CCG,Fer4_7,Fer4_8 k141_32175_2 1117647.M5M_07575 4.59e-77 248.0 COG0277@1|root,COG0277@2|Bacteria,1MVYV@1224|Proteobacteria,1RN4G@1236|Gammaproteobacteria,1J5UK@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C COG0277 FAD FMN-containing dehydrogenases glcE GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616 - ko:K11472 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001 - - iETEC_1333.ETEC_3246 FAD-oxidase_C,FAD_binding_4 k141_32175_4 1042377.AFPJ01000036_gene1147 3.16e-197 555.0 COG4299@1|root,COG4299@2|Bacteria,1R5FB@1224|Proteobacteria,1S1E0@1236|Gammaproteobacteria,467VN@72275|Alteromonadaceae 1236|Gammaproteobacteria S COGs COG4299 conserved - - - - - - - - - - - - DUF1624,DUF5009 k141_32175_5 1042377.AFPJ01000036_gene1146 1.84e-196 563.0 COG2173@1|root,COG3876@1|root,COG2173@2|Bacteria,COG3876@2|Bacteria,1MX3S@1224|Proteobacteria,1RSA3@1236|Gammaproteobacteria,465YH@72275|Alteromonadaceae 1236|Gammaproteobacteria M protein conserved in bacteria - - - - - - - - - - - - DUF1343 k141_32175_6 1042377.AFPJ01000036_gene1146 3.47e-96 300.0 COG2173@1|root,COG3876@1|root,COG2173@2|Bacteria,COG3876@2|Bacteria,1MX3S@1224|Proteobacteria,1RSA3@1236|Gammaproteobacteria,465YH@72275|Alteromonadaceae 1236|Gammaproteobacteria M protein conserved in bacteria - - - - - - - - - - - - DUF1343 k141_16966_3 1279017.AQYJ01000028_gene2379 2.26e-234 656.0 COG0635@1|root,COG0635@2|Bacteria,1MV1I@1224|Proteobacteria,1RN1Y@1236|Gammaproteobacteria,46465@72275|Alteromonadaceae 1236|Gammaproteobacteria H Belongs to the anaerobic coproporphyrinogen-III oxidase family hemN - 1.3.98.3 ko:K02495 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R06895 RC00884 ko00000,ko00001,ko00002,ko01000 - - - HemN_C,Radical_SAM k141_3899_1 218284.CCDN010000001_gene227 3.04e-135 390.0 COG0827@1|root,COG0827@2|Bacteria,1TRIQ@1239|Firmicutes,4H9SE@91061|Bacilli,1ZBZ7@1386|Bacillus 91061|Bacilli L DNA methylase ytxK - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_Mtase k141_3899_2 218284.CCDN010000001_gene226 2.86e-111 320.0 COG2077@1|root,COG2077@2|Bacteria,1V474@1239|Firmicutes,4HFMW@91061|Bacilli,1ZARA@1386|Bacillus 91061|Bacilli O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides tpx - 1.11.1.15 ko:K11065 - - - - ko00000,ko01000 - - - AhpC-TSA,Redoxin k141_384_1 1116375.VEJY3_10095 1.11e-89 278.0 COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,1RQR7@1236|Gammaproteobacteria,1XUQ4@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria VP1916 - - ko:K21470 - - - - ko00000,ko01002,ko01011 - - - PG_binding_1,YkuD k141_10960_1 1306174.JODP01000006_gene3601 1.76e-06 52.4 COG1597@1|root,COG1597@2|Bacteria,2I8DY@201174|Actinobacteria 201174|Actinobacteria I Diacylglycerol kinase - - - - - - - - - - - - DAGK_cat k141_10960_2 1042377.AFPJ01000016_gene134 5.56e-89 263.0 COG3313@1|root,COG3313@2|Bacteria,1N711@1224|Proteobacteria,1S5BC@1236|Gammaproteobacteria,467HV@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF1289) - - - ko:K06938 - - - - ko00000 - - - DUF1289 k141_10960_3 1279017.AQYJ01000026_gene55 9.65e-241 685.0 COG1049@1|root,COG1049@2|Bacteria,1MVCR@1224|Proteobacteria,1RNMC@1236|Gammaproteobacteria,46445@72275|Alteromonadaceae 1236|Gammaproteobacteria C Belongs to the aconitase IPM isomerase family acnB - 4.2.1.3,4.2.1.99 ko:K01682 ko00020,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173 R01324,R01325,R01900,R04425 RC00497,RC00498,RC00618,RC01153 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_2_N,Aconitase_B_N k141_27556_1 1453501.JELR01000002_gene217 1.71e-272 750.0 COG0006@1|root,COG0006@2|Bacteria,1MURT@1224|Proteobacteria,1RMKT@1236|Gammaproteobacteria,465D3@72275|Alteromonadaceae 1236|Gammaproteobacteria E Splits dipeptides with a prolyl residue in the C- terminal position pepQ - 3.4.13.9 ko:K01271 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M24 k141_27556_2 1279017.AQYJ01000023_gene3093 6.05e-116 354.0 COG1228@1|root,COG1228@2|Bacteria,1MY4V@1224|Proteobacteria,1RZRK@1236|Gammaproteobacteria,46606@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Amidohydrolase family - - - - - - - - - - - - Amidohydro_1 k141_5014_1 1116375.VEJY3_06475 1.74e-81 250.0 COG0614@1|root,COG0614@2|Bacteria,1MUSZ@1224|Proteobacteria,1RPUH@1236|Gammaproteobacteria,1XVTG@135623|Vibrionales 135623|Vibrionales P ABC-type Fe3 -hydroxamate transport system, periplasmic component - - - ko:K02016 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - Peripla_BP_2 k141_6341_1 1179226.AJXO01000025_gene140 2.05e-41 144.0 COG1999@1|root,COG1999@2|Bacteria,1V4FW@1239|Firmicutes,4HHC4@91061|Bacilli,4GYXI@90964|Staphylococcaceae 91061|Bacilli S SCO1/SenC ypmQ_1 - - ko:K07152 - - - - ko00000,ko03029 - - - SCO1-SenC k141_33542_1 1042377.AFPJ01000032_gene2782 3.4e-60 192.0 COG0589@1|root,COG0589@2|Bacteria 2|Bacteria T AMP binding - - - ko:K14055 - - - - ko00000 - - - Usp k141_33542_2 1453501.JELR01000002_gene1436 1.9e-22 92.0 COG2350@1|root,COG2350@2|Bacteria,1NCHB@1224|Proteobacteria,1SG2M@1236|Gammaproteobacteria,46BI7@72275|Alteromonadaceae 1236|Gammaproteobacteria S YCII-related domain - - - - - - - - - - - - YCII k141_3900_1 218284.CCDN010000004_gene3035 8.52e-30 115.0 COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,4HA95@91061|Bacilli,1ZCW9@1386|Bacillus 91061|Bacilli E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids alr - 5.1.1.1,5.1.1.5 ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 - R00401 RC00285 ko00000,ko00001,ko01000,ko01011 - - - Ala_racemase_C,Ala_racemase_N k141_3900_2 218284.CCDN010000004_gene3034 4.72e-55 172.0 COG0864@1|root,COG0864@2|Bacteria,1VA28@1239|Firmicutes,4HKPU@91061|Bacilli,1ZGYI@1386|Bacillus 91061|Bacilli K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain ndoAI GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K07723 - - - - ko00000,ko02048,ko03000 - - - RHH_1 k141_14530_1 1283300.ATXB01000002_gene3045 1.04e-49 167.0 COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,1S2WI@1236|Gammaproteobacteria,1XEYK@135618|Methylococcales 135618|Methylococcales O Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins - - 2.1.1.77 ko:K00573 - - - - ko00000,ko01000 - - - PCMT k141_14530_2 1316936.K678_05011 0.000389 42.4 COG1355@1|root,COG2078@1|root,COG1355@2|Bacteria,COG2078@2|Bacteria,1MXK5@1224|Proteobacteria,2U13I@28211|Alphaproteobacteria,2JQVM@204441|Rhodospirillales 204441|Rhodospirillales S Belongs to the MEMO1 family - - - ko:K06990 - - - - ko00000,ko04812 - - - AMMECR1,Memo k141_19300_1 298386.PBPRB1396 2.46e-178 500.0 COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,1S1WF@1236|Gammaproteobacteria,1Y2TW@135623|Vibrionales 135623|Vibrionales L Phage integrase family - - - - - - - - - - - - Phage_int_SAM_4,Phage_integrase k141_19300_2 298386.PBPRB1693 6.95e-200 560.0 COG0582@1|root,COG0582@2|Bacteria,1QUB8@1224|Proteobacteria,1T3R3@1236|Gammaproteobacteria,1Y35S@135623|Vibrionales 1236|Gammaproteobacteria L Putative transposase - - - - - - - - - - - - Y2_Tnp,Zn_Tnp_IS91 k141_3929_1 441769.ABFU01000060_gene592 1e-38 136.0 COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,4HJN1@91061|Bacilli,1ZG2C@1386|Bacillus 91061|Bacilli CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - - - - - - - - - - AhpC-TSA k141_10974_1 1502852.FG94_01893 6.7e-86 271.0 COG3507@1|root,COG3507@2|Bacteria,1NNX4@1224|Proteobacteria 1224|Proteobacteria G Belongs to the glycosyl hydrolase 43 family xynA - 3.2.1.37,3.2.1.55 ko:K01198,ko:K01209 ko00520,ko01100,map00520,map01100 - R01433,R01762 RC00467 ko00000,ko00001,ko01000 - GH43,GH51 - Glyco_hydro_43 k141_29943_3 1042377.AFPJ01000043_gene893 2.36e-34 120.0 2EFYJ@1|root,339QQ@2|Bacteria,1NH5C@1224|Proteobacteria,1SGE6@1236|Gammaproteobacteria,468WH@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_1435_1 1461580.CCAS010000093_gene4433 3.26e-93 290.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,1ZBIW@1386|Bacillus 91061|Bacilli V COG1132 ABC-type multidrug transport system, ATPase and permease components mdlB - - ko:K06147,ko:K18890 ko02010,map02010 M00707 - - ko00000,ko00001,ko00002,ko02000 3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran k141_33568_1 218284.CCDN010000001_gene1071 2.73e-64 211.0 COG0514@1|root,COG0514@2|Bacteria,1TPN5@1239|Firmicutes,4H9QP@91061|Bacilli,1ZB1X@1386|Bacillus 91061|Bacilli L DNA helicase recQ GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009378,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.6.4.12 ko:K03654 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecQ_Zn_bind k141_2704_1 1347086.CCBA010000003_gene3811 7.97e-122 365.0 COG0843@1|root,COG0843@2|Bacteria,1TP2U@1239|Firmicutes,4HA4X@91061|Bacilli,1ZBD5@1386|Bacillus 91061|Bacilli C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B qoxB GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009486,GO:0009987,GO:0015002,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016310,GO:0016491,GO:0016679,GO:0016682,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0034220,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0098655,GO:0098660,GO:0098662,GO:1901135,GO:1901360,GO:1901564,GO:1902600 1.10.3.12 ko:K02827 ko00190,ko01100,map00190,map01100 M00416 R09492 RC00819 ko00000,ko00001,ko00002,ko01000 3.D.4.1 - - COX1 k141_22927_1 218284.CCDN010000005_gene3246 8.85e-200 563.0 COG0534@1|root,COG0534@2|Bacteria,1TQMT@1239|Firmicutes,4H9Y2@91061|Bacilli,1ZBQK@1386|Bacillus 91061|Bacilli V Mate efflux family protein yisQ - - - - - - - - - - - MatE k141_6363_1 1268072.PSAB_12205 1.48e-35 133.0 COG2603@1|root,COG2603@2|Bacteria,1TQ8T@1239|Firmicutes,4HBX4@91061|Bacilli,26UGA@186822|Paenibacillaceae 91061|Bacilli S tRNA 2-selenouridine synthase selU - - ko:K06917 - - - - ko00000,ko01000,ko03016 - - - Rhodanese k141_26622_1 218284.CCDN010000001_gene1143 5.53e-33 114.0 2E85E@1|root,332IZ@2|Bacteria,1VHMN@1239|Firmicutes,4HPYR@91061|Bacilli,1ZIUT@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF4264) ypmA - - - - - - - - - - - DUF4264 k141_26622_2 218284.CCDN010000001_gene1144 2.73e-87 259.0 COG5353@1|root,COG5353@2|Bacteria,1VA2H@1239|Firmicutes,4HNMM@91061|Bacilli,1ZFVJ@1386|Bacillus 91061|Bacilli S protein conserved in bacteria ypmB - - - - - - - - - - - PepSY k141_24051_1 529818.AMSG_07064T0 1.81e-50 168.0 COG0652@1|root,2S41Q@2759|Eukaryota 529818.AMSG_07064T0|- O Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD - - - - - - - - - - - - - k141_24051_2 118161.KB235922_gene3979 3.75e-05 46.6 COG3439@1|root,COG3439@2|Bacteria,1G8MR@1117|Cyanobacteria 1117|Cyanobacteria S Domain of unknown function DUF302 - - - - - - - - - - - - DUF302 k141_5038_1 1116375.VEJY3_21846 1.64e-62 196.0 COG0546@1|root,COG0546@2|Bacteria,1RHAA@1224|Proteobacteria,1S7HQ@1236|Gammaproteobacteria,1XWVY@135623|Vibrionales 135623|Vibrionales S phosphatases - - - - - - - - - - - - HAD_2 k141_5038_2 1116375.VEJY3_21851 3.4e-106 306.0 COG0783@1|root,COG0783@2|Bacteria,1RAC5@1224|Proteobacteria,1S3UH@1236|Gammaproteobacteria,1XWX7@135623|Vibrionales 135623|Vibrionales P Belongs to the Dps family dps - - ko:K04047 - - - - ko00000,ko03036 - - - Ferritin k141_5038_3 1219076.N646_4597 0.0 946.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XVJY@135623|Vibrionales 135623|Vibrionales T COG0840 Methyl-accepting chemotaxis protein VPA0562 - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - 4HB_MCP_1,HAMP,MCPsignal k141_35913_1 1430331.EP10_09545 1.28e-21 93.6 COG0466@1|root,COG0466@2|Bacteria,1TNYG@1239|Firmicutes,4HAZK@91061|Bacilli,1WEEV@129337|Geobacillus 91061|Bacilli O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner lon GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.4.21.53 ko:K01338 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - AAA,LON_substr_bdg,Lon_C k141_35913_2 218284.CCDN010000001_gene595 1.76e-121 348.0 COG0218@1|root,COG0218@2|Bacteria,1TSPW@1239|Firmicutes,4HBXZ@91061|Bacilli,1ZBX7@1386|Bacillus 91061|Bacilli D Necessary for normal cell division and for the maintenance of normal septation engB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K03978 - - - - ko00000,ko03036 - - - MMR_HSR1 k141_33569_1 1042377.AFPJ01000032_gene2750 2.38e-86 281.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,464X3@72275|Alteromonadaceae 1236|Gammaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran k141_3931_1 218284.CCDN010000004_gene3157 8.26e-177 502.0 COG0635@1|root,COG0635@2|Bacteria,1TREM@1239|Firmicutes,4HC2D@91061|Bacilli,1ZCRB@1386|Bacillus 91061|Bacilli H coproporphyrinogen III oxidase hemZ - - - - - - - - - - - Radical_SAM k141_10976_1 1121940.AUDZ01000015_gene1374 6.98e-83 256.0 COG1485@1|root,COG1485@2|Bacteria,1MWH4@1224|Proteobacteria,1RMXV@1236|Gammaproteobacteria,1XIM6@135619|Oceanospirillales 135619|Oceanospirillales S AFG1-like ATPase - - - ko:K06916 - - - - ko00000,ko03036 - - - AFG1_ATPase k141_12276_1 218284.CCDN010000002_gene2057 4.39e-48 156.0 COG3871@1|root,COG3871@2|Bacteria,1V6MX@1239|Firmicutes,4HIYZ@91061|Bacilli,1ZH2Z@1386|Bacillus 91061|Bacilli S general stress protein ydaG - - - - - - - - - - - Putative_PNPOx,Pyrid_ox_like k141_13421_1 1279017.AQYJ01000024_gene988 8.56e-296 818.0 COG0129@1|root,COG0129@2|Bacteria,1MU3T@1224|Proteobacteria,1RMNA@1236|Gammaproteobacteria,464QM@72275|Alteromonadaceae 1236|Gammaproteobacteria EG Belongs to the IlvD Edd family edd GO:0003674,GO:0003824,GO:0004456,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019520,GO:0019521,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0046176,GO:0046177,GO:0046395,GO:0071704,GO:0072329,GO:1901575 4.2.1.12 ko:K01690 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 M00008 R02036 RC00543 ko00000,ko00001,ko00002,ko01000 - - iEcolC_1368.EcolC_1781,iJN746.PP_1010,iPC815.YPO2533,iYL1228.KPN_02366 ILVD_EDD k141_393_1 1123236.KB899382_gene2229 1.89e-106 347.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria,4652I@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec k141_3932_1 218284.CCDN010000005_gene3427 1.99e-93 274.0 COG1051@1|root,COG1051@2|Bacteria,1V4TX@1239|Firmicutes,4HH70@91061|Bacilli,1ZGXJ@1386|Bacillus 91061|Bacilli F Belongs to the Nudix hydrolase family - - - - - - - - - - - - NUDIX k141_29944_1 42565.FP66_02800 9.97e-31 112.0 COG0212@1|root,COG0212@2|Bacteria,1MZG0@1224|Proteobacteria,1S612@1236|Gammaproteobacteria,1XJPQ@135619|Oceanospirillales 135619|Oceanospirillales H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family - - 6.3.3.2 ko:K01934 ko00670,ko01100,map00670,map01100 - R02301 RC00183 ko00000,ko00001,ko01000 - - - 5-FTHF_cyc-lig k141_29944_2 1042209.HK44_014060 6.19e-07 47.0 2B4B1@1|root,31X2H@2|Bacteria,1QRJ2@1224|Proteobacteria,1RUJM@1236|Gammaproteobacteria,1YR37@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_9780_1 1266909.AUAG01000051_gene326 2.57e-67 226.0 COG0457@1|root,COG0457@2|Bacteria,1R50I@1224|Proteobacteria,1RSP6@1236|Gammaproteobacteria,1WY6N@135613|Chromatiales 135613|Chromatiales S Tetratricopeptide repeat - - - - - - - - - - - - - k141_33570_1 1453501.JELR01000001_gene1800 3.1e-99 303.0 COG0793@1|root,COG0793@2|Bacteria,1N5BU@1224|Proteobacteria,1SF0G@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Belongs to the peptidase S41A family - - - - - - - - - - - - - k141_27567_1 1347087.CBYO010000022_gene3930 3.24e-38 130.0 COG4933@1|root,COG4933@2|Bacteria,1VBSE@1239|Firmicutes,4HMCX@91061|Bacilli 91061|Bacilli S ASCH domain - - - - - - - - - - - - ASCH k141_27567_2 171693.BN988_02229 1.65e-39 140.0 COG1063@1|root,COG1063@2|Bacteria,1VRPE@1239|Firmicutes,4HU28@91061|Bacilli 91061|Bacilli E alcohol dehydrogenase - - 1.1.1.1 ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N k141_19303_1 344747.PM8797T_27819 3.54e-24 97.4 COG5620@1|root,COG5620@2|Bacteria,2J3WW@203682|Planctomycetes 203682|Planctomycetes S Domain of unknown function (DUF1851) - - - - - - - - - - - - DUF1851 k141_14532_1 338969.Rfer_0385 8.14e-43 154.0 COG0508@1|root,COG0508@2|Bacteria,1MUGY@1224|Proteobacteria,2VN6N@28216|Betaproteobacteria,4AEZ2@80864|Comamonadaceae 28216|Betaproteobacteria C e3 binding domain - - 2.3.1.12 ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding k141_22929_1 1121091.AUMP01000003_gene2562 1.48e-21 90.5 COG3935@1|root,COG3935@2|Bacteria,1V6IW@1239|Firmicutes,4HJ9G@91061|Bacilli 91061|Bacilli L Domain of unknown function (DUF4373) - - - - - - - - - - - - DUF4373,DnaB_2,Rep_Org_C k141_22929_2 1295642.H839_08129 6.17e-10 56.6 COG3655@1|root,COG3655@2|Bacteria 2|Bacteria K Transcriptional regulator - - - ko:K07727 - - - - ko00000,ko03000 - - - HTH_26,HTH_3 k141_13422_1 426117.M446_0892 1.98e-11 70.9 COG0747@1|root,COG0747@2|Bacteria,1MUP8@1224|Proteobacteria,2TQXX@28211|Alphaproteobacteria,1JRA2@119045|Methylobacteriaceae 28211|Alphaproteobacteria E PFAM extracellular solute-binding protein family 5 appA - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 k141_24053_1 1294265.JCM21738_4935 2.03e-64 204.0 COG0448@1|root,COG0448@2|Bacteria,1TPZ3@1239|Firmicutes,4H9UQ@91061|Bacilli,1ZBVM@1386|Bacillus 91061|Bacilli G Glucose-1-phosphate adenylyltransferase, GlgD subunit glgD - 2.7.7.27 ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transferase k141_24053_2 1294265.JCM21738_4934 5.04e-48 162.0 COG0448@1|root,COG0448@2|Bacteria,1TNZW@1239|Firmicutes,4HAZX@91061|Bacilli,1ZCF2@1386|Bacillus 91061|Bacilli G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans glgC GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008878,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0070566,GO:0071704,GO:1901576 2.7.7.27 ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transferase k141_18201_1 218284.CCDN010000001_gene1865 1.06e-74 231.0 COG1079@1|root,COG1079@2|Bacteria,1TP8Y@1239|Firmicutes,4HAX4@91061|Bacilli,1ZAYF@1386|Bacillus 91061|Bacilli S Belongs to the binding-protein-dependent transport system permease family yufQ - - ko:K02057 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - BPD_transp_2 k141_20442_2 1403313.AXBR01000003_gene3983 8.14e-207 586.0 COG1680@1|root,COG1680@2|Bacteria,1U828@1239|Firmicutes,4HA0Q@91061|Bacilli,1ZBJ0@1386|Bacillus 91061|Bacilli V Belongs to the UPF0214 family ybbE - 3.4.16.4 ko:K21469 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - Beta-lactamase k141_20442_3 247634.GPB2148_1975 1.35e-19 80.9 2BTPG@1|root,32NWH@2|Bacteria,1QJ6Y@1224|Proteobacteria,1TH4I@1236|Gammaproteobacteria,1J79V@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Cysteine-rich CPXCG - - - - - - - - - - - - Cys_rich_CPXG k141_20442_4 1042377.AFPJ01000032_gene2722 3.52e-116 340.0 COG1073@1|root,COG1073@2|Bacteria 2|Bacteria S thiolester hydrolase activity MA20_16590 - - ko:K06889,ko:K07397 - - - - ko00000 - - - Hydrolase_4,OsmC k141_35914_2 1121090.KB894692_gene2200 6.31e-14 70.9 COG0289@1|root,COG0289@2|Bacteria,1TR9D@1239|Firmicutes,4HA5X@91061|Bacilli,1ZAWD@1386|Bacillus 91061|Bacilli E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate dapB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R04198,R04199 RC00478 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU22490 DapB_C,DapB_N k141_2707_1 218284.CCDN010000001_gene1828 3.18e-121 360.0 COG0621@1|root,COG0621@2|Bacteria,1TNYN@1239|Firmicutes,4HAAS@91061|Bacilli,1ZBMF@1386|Bacillus 91061|Bacilli J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine miaB GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035597,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360 2.8.4.3 ko:K06168 - - R10645,R10646,R10647 RC00003,RC00980,RC03221,RC03222 ko00000,ko01000,ko03016 - - - Radical_SAM,TRAM,UPF0004 k141_15772_1 1453501.JELR01000002_gene848 0.0 885.0 COG4225@1|root,COG4225@2|Bacteria,1MU2J@1224|Proteobacteria,1RR65@1236|Gammaproteobacteria,4660R@72275|Alteromonadaceae 1236|Gammaproteobacteria S unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins - - - - - - - - - - - - DUF4861,Glyco_hydro_88 k141_10978_1 926566.Terro_3291 5.72e-40 137.0 2CCJF@1|root,32RVW@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k141_1437_1 1196031.ALEG01000031_gene2350 2.03e-86 263.0 COG0697@1|root,COG0697@2|Bacteria,1V2GJ@1239|Firmicutes,4HV8D@91061|Bacilli,1ZRP6@1386|Bacillus 91061|Bacilli EG EamA-like transporter family - - - - - - - - - - - - EamA k141_1437_2 218284.CCDN010000001_gene281 1.3e-06 48.5 COG1522@1|root,COG1522@2|Bacteria,1V88V@1239|Firmicutes,4IS29@91061|Bacilli,1ZS0P@1386|Bacillus 91061|Bacilli K helix_turn_helix ASNC type - - - - - - - - - - - - AsnC_trans_reg,HTH_24 k141_3933_1 314345.SPV1_11716 1.58e-74 228.0 COG3224@1|root,COG3224@2|Bacteria,1QUU7@1224|Proteobacteria 1224|Proteobacteria S Antibiotic biosynthesis monooxygenase - - - ko:K09932 - - - - ko00000 - - - ABM k141_3933_2 1122194.AUHU01000006_gene551 9.64e-95 298.0 COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,1RNCM@1236|Gammaproteobacteria,464YW@72275|Alteromonadaceae 1236|Gammaproteobacteria C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - - - - - - - - - - Ald_Xan_dh_C2 k141_18202_1 1453501.JELR01000001_gene2476 1.91e-81 269.0 COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,1RNCU@1236|Gammaproteobacteria,464IX@72275|Alteromonadaceae 1236|Gammaproteobacteria L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd GO:0000715,GO:0000716,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006283,GO:0006289,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008094,GO:0008150,GO:0008152,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0015616,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031326,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0043175,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051276,GO:0051716,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF k141_2708_2 1122134.KB893650_gene1591 2.64e-30 109.0 2CCNX@1|root,32RW4@2|Bacteria,1N3P1@1224|Proteobacteria,1SAFG@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_35915_1 665959.HMPREF1013_04280 8.04e-33 125.0 COG0577@1|root,COG0577@2|Bacteria,1TPSE@1239|Firmicutes,4HCAX@91061|Bacilli,1ZBS7@1386|Bacillus 91061|Bacilli V ABC transporter (permease) YclI yclI GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD k141_26624_1 1453501.JELR01000002_gene129 2.45e-223 622.0 COG3203@1|root,COG3203@2|Bacteria,1MX4Q@1224|Proteobacteria,1RY5B@1236|Gammaproteobacteria,4654M@72275|Alteromonadaceae 1236|Gammaproteobacteria M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - - - - - - - - - - Porin_2 k141_26624_2 1453501.JELR01000002_gene128 1.62e-40 135.0 COG4327@1|root,COG4327@2|Bacteria,1N0TK@1224|Proteobacteria,1S8V9@1236|Gammaproteobacteria,468I1@72275|Alteromonadaceae 1236|Gammaproteobacteria S membrane - - - - - - - - - - - - DUF4212 k141_20443_1 218284.CCDN010000007_gene3881 5.3e-50 172.0 2EF7A@1|root,33909@2|Bacteria,1VJW7@1239|Firmicutes,4HQS6@91061|Bacilli,1ZHDY@1386|Bacillus 91061|Bacilli - - gvpT - - - - - - - - - - - - k141_22931_1 218284.CCDN010000010_gene4358 3.02e-36 123.0 COG0255@1|root,COG0255@2|Bacteria,1VEME@1239|Firmicutes,4HNUP@91061|Bacilli,1ZI7W@1386|Bacillus 91061|Bacilli J Belongs to the universal ribosomal protein uL29 family rpmC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02904 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L29 k141_22931_2 218284.CCDN010000010_gene4359 2.48e-99 288.0 COG0197@1|root,COG0197@2|Bacteria,1V1AY@1239|Firmicutes,4HFPN@91061|Bacilli,1ZFMZ@1386|Bacillus 91061|Bacilli J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs rplP GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - ko:K02878 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L16 k141_1460_1 198467.NP92_01220 2.93e-70 239.0 COG0745@1|root,COG5000@1|root,COG5002@1|root,COG0745@2|Bacteria,COG5000@2|Bacteria,COG5002@2|Bacteria,1U7NI@1239|Firmicutes,4HA3E@91061|Bacilli,21W0U@150247|Anoxybacillus 91061|Bacilli T PAS fold - - - - - - - - - - - - GAF,GAF_3,HAMP,HATPase_c,HisKA,Response_reg k141_20460_1 1042377.AFPJ01000028_gene2162 2.72e-57 201.0 COG0457@1|root,COG0457@2|Bacteria,1MXSS@1224|Proteobacteria,1S157@1236|Gammaproteobacteria,467PR@72275|Alteromonadaceae 1236|Gammaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16,TPR_6 k141_20460_2 1279017.AQYJ01000028_gene2076 4.61e-89 265.0 2B4XH@1|root,31XQC@2|Bacteria,1RHJF@1224|Proteobacteria,1S3S1@1236|Gammaproteobacteria,467JQ@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_22939_1 218284.CCDN010000007_gene3797 6.47e-136 402.0 COG0445@1|root,COG0445@2|Bacteria,1TQ4B@1239|Firmicutes,4HA6S@91061|Bacilli,1ZB67@1386|Bacillus 91061|Bacilli D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 gidA GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - ko:K03495 - - R08701 RC00053,RC00209,RC00870 ko00000,ko03016,ko03036 - - - GIDA,GIDA_assoc k141_34788_1 1202768.JROF01000024_gene3737 5.45e-06 50.1 COG0351@1|root,arCOG00020@2157|Archaea,2XSW8@28890|Euryarchaeota,23S8Z@183963|Halobacteria 183963|Halobacteria H COG0351 Hydroxymethylpyrimidine phosphomethylpyrimidine kinase thiD - 2.5.1.3,2.7.1.49,2.7.4.7 ko:K00941,ko:K21219 ko00730,ko01100,map00730,map01100 M00127 R03223,R03471,R04509,R10712 RC00002,RC00017,RC00224,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 - - - Phos_pyr_kin,ThiP_synth k141_34788_2 1248760.ANFZ01000009_gene801 1.17e-05 49.3 COG2041@1|root,COG2041@2|Bacteria,1MX9E@1224|Proteobacteria,2TRK0@28211|Alphaproteobacteria,2K0UU@204457|Sphingomonadales 204457|Sphingomonadales S Mo-co oxidoreductase dimerisation domain - - - - - - - - - - - - Mo-co_dimer,Oxidored_molyb k141_32536_16 674977.VMC_26360 4.44e-64 214.0 COG1289@1|root,COG1289@2|Bacteria,1QJEM@1224|Proteobacteria,1SMXK@1236|Gammaproteobacteria,1XUKV@135623|Vibrionales 135623|Vibrionales S Aromatic acid exporter family member 1 VPA1578 - - - - - - - - - - - FUSC k141_23266_1 498211.CJA_2628 4.24e-46 168.0 COG2217@1|root,COG2608@1|root,COG2217@2|Bacteria,COG2608@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,1FGJW@10|Cellvibrio 1236|Gammaproteobacteria P Putative metal-binding domain of cation transport ATPase ccoI - 3.6.3.4 ko:K01533 - - R00086 RC00002 ko00000,ko01000 3.A.3.5 - - ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase k141_1687_1 218284.CCDN010000006_gene3548 1.16e-67 216.0 COG0665@1|root,COG0665@2|Bacteria,1TR1R@1239|Firmicutes,4HB8E@91061|Bacilli,1ZC21@1386|Bacillus 91061|Bacilli E FAD dependent oxidoreductase - - - - - - - - - - - - DAO k141_33889_2 1116375.VEJY3_02435 0.0 1051.0 COG3275@1|root,COG3275@2|Bacteria,1QUB1@1224|Proteobacteria,1T1RX@1236|Gammaproteobacteria,1XU1C@135623|Vibrionales 135623|Vibrionales T regulator of cell autolysis yehU - 2.7.13.3 ko:K02478 - - - - ko00000,ko01000,ko01001,ko02022 - - - 5TM-5TMR_LYT,GAF_3,His_kinase,SpoVT_C k141_33889_3 1116375.VEJY3_02430 5.81e-162 454.0 COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,1RMJJ@1236|Gammaproteobacteria,1XU8Z@135623|Vibrionales 135623|Vibrionales K COG3279 Response regulator of the LytR AlgR family yehT GO:0000156,GO:0000160,GO:0003674,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0023052,GO:0035556,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007 - ko:K02477 - - - - ko00000,ko02022 - - - LytTR,Response_reg k141_17193_1 373994.Riv7116_3033 6.63e-82 270.0 COG0577@1|root,COG0577@2|Bacteria,1G0Z7@1117|Cyanobacteria 1117|Cyanobacteria V ABC-type transport system involved in lipoprotein release permease component - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD k141_17193_2 991905.SL003B_1031 4.57e-109 333.0 COG0845@1|root,COG0845@2|Bacteria,1Q112@1224|Proteobacteria,2V906@28211|Alphaproteobacteria,4BSRF@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K02005 - - - - ko00000 - - - HlyD_3 k141_17193_3 551789.ATVJ01000001_gene796 5.02e-196 574.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1MUJ3@1224|Proteobacteria,2U4U7@28211|Alphaproteobacteria,43XCF@69657|Hyphomonadaceae 28211|Alphaproteobacteria EU X-Pro dipeptidyl-peptidase (S15 family) - - - - - - - - - - - - PD40,Peptidase_S9,Peptidase_S9_N k141_13839_1 1535422.ND16A_3283 1.89e-52 188.0 COG0823@1|root,COG3710@1|root,COG0823@2|Bacteria,COG3710@2|Bacteria,1RIFT@1224|Proteobacteria,1S7XY@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Transcriptional regulatory protein, C terminal - - - - - - - - - - - - PD40,Trans_reg_C k141_13839_2 1134474.O59_000474 4.73e-35 136.0 COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,1RYK4@1236|Gammaproteobacteria 1236|Gammaproteobacteria V Beta-lactamase - - - - - - - - - - - - Beta-lactamase k141_18514_1 1123073.KB899241_gene2844 1.57e-71 237.0 COG1566@1|root,COG1566@2|Bacteria,1RJ3I@1224|Proteobacteria,1S7BS@1236|Gammaproteobacteria,1X4Y6@135614|Xanthomonadales 135614|Xanthomonadales V Protein of unknown function (DUF3667) - - - - - - - - - - - - DUF3667 k141_18514_2 1279017.AQYJ01000020_gene1278 7.72e-247 685.0 COG0260@1|root,COG0260@2|Bacteria,1MUIN@1224|Proteobacteria,1RNFI@1236|Gammaproteobacteria,465XH@72275|Alteromonadaceae 1236|Gammaproteobacteria E Probably plays an important role in intracellular peptide degradation pepB - 3.4.11.23 ko:K07751 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - DUF3663,Peptidase_M17 k141_18514_3 1453501.JELR01000002_gene856 1.69e-190 546.0 COG1040@1|root,COG1040@2|Bacteria,1REX9@1224|Proteobacteria,1S568@1236|Gammaproteobacteria,4671D@72275|Alteromonadaceae 1236|Gammaproteobacteria S competence protein - - - - - - - - - - - - - k141_18514_4 1279017.AQYJ01000020_gene1281 8.52e-233 653.0 COG0705@1|root,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,1RZ5Q@1236|Gammaproteobacteria,46767@72275|Alteromonadaceae 1236|Gammaproteobacteria S membrane protein (homolog of Drosophila rhomboid) - - - - - - - - - - - - Rhomboid k141_18514_5 1279017.AQYJ01000020_gene1282 1.17e-282 800.0 COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,1RMYY@1236|Gammaproteobacteria,465WZ@72275|Alteromonadaceae 1236|Gammaproteobacteria M Mechanosensitive ion channel kefA - - - - - - - - - - - MS_channel k141_18514_7 1279017.AQYJ01000020_gene1284 3.33e-145 423.0 COG0845@1|root,COG0845@2|Bacteria,1MV1T@1224|Proteobacteria,1RQTS@1236|Gammaproteobacteria,469SX@72275|Alteromonadaceae 1236|Gammaproteobacteria M Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - - - - - - - - - - HlyD_3,HlyD_D23 k141_18514_8 1279017.AQYJ01000020_gene1285 0.0 911.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,464AK@72275|Alteromonadaceae 1236|Gammaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran k141_35098_1 864051.BurJ1DRAFT_0403 2.3e-50 176.0 2DB7W@1|root,2Z7P1@2|Bacteria,1N65F@1224|Proteobacteria,2VK71@28216|Betaproteobacteria,1KJ1D@119065|unclassified Burkholderiales 28216|Betaproteobacteria S Domain of unknown function (DUF4331) - - - - - - - - - - - - DUF4331 k141_21967_1 1279017.AQYJ01000027_gene1667 8.98e-93 283.0 COG2223@1|root,COG2223@2|Bacteria,1MU27@1224|Proteobacteria,1RMUK@1236|Gammaproteobacteria,4652C@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG2223 Nitrate nitrite transporter narK1 - - ko:K02575 ko00910,map00910 M00615 - - ko00000,ko00001,ko00002,ko02000 2.A.1.8 - - MFS_1 k141_24325_1 1279017.AQYJ01000028_gene2268 1.04e-176 522.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MWTT@1224|Proteobacteria,1RP0H@1236|Gammaproteobacteria,46CKB@72275|Alteromonadaceae 1236|Gammaproteobacteria P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec k141_6565_1 1399115.U719_14965 5.31e-43 144.0 COG3238@1|root,COG3238@2|Bacteria,1V4Z7@1239|Firmicutes,4HI7N@91061|Bacilli 91061|Bacilli S Putative inner membrane exporter, YdcZ - - - ko:K09936 ko02024,map02024 - - - ko00000,ko00001,ko02000 2.A.7.21 - - DMT_YdcZ k141_6565_2 1444310.JANV01000123_gene853 1.46e-16 75.1 COG3238@1|root,COG3238@2|Bacteria,1V73B@1239|Firmicutes,4HH3Y@91061|Bacilli,1ZHPB@1386|Bacillus 91061|Bacilli S Putative inner membrane exporter, YdcZ - - - ko:K09936 ko02024,map02024 - - - ko00000,ko00001,ko02000 2.A.7.21 - - DMT_YdcZ k141_5445_1 1294265.JCM21738_4136 2.8e-54 171.0 COG0288@1|root,COG0288@2|Bacteria,1UAXT@1239|Firmicutes,4IMAM@91061|Bacilli,1ZJN9@1386|Bacillus 91061|Bacilli P reversible hydration of carbon dioxide - - - - - - - - - - - - - k141_7640_2 1279017.AQYJ01000028_gene2033 6.29e-301 827.0 COG0301@1|root,COG0607@1|root,COG0301@2|Bacteria,COG0607@2|Bacteria,1MWD3@1224|Proteobacteria,1RNZT@1236|Gammaproteobacteria,4664X@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS thiI GO:0000049,GO:0002937,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017144,GO:0018130,GO:0019438,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042364,GO:0042723,GO:0042724,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.8.1.4 ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07461 - ko00000,ko00001,ko01000,ko03016 - - iECNA114_1301.ECNA114_0400,iECO26_1355.ECO26_0455,iECSF_1327.ECSF_0383,iSDY_1059.SDY_0307 THUMP,ThiI k141_14773_1 796606.BMMGA3_11670 1.14e-23 97.4 COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,4HBAU@91061|Bacilli,1ZBV8@1386|Bacillus 91061|Bacilli G Glucokinase glcK GO:0003674,GO:0003824,GO:0004340,GO:0004396,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044464,GO:0046835,GO:0051156,GO:0071704,GO:1901135 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS07790 ROK k141_29065_1 1273538.G159_08490 1.16e-119 350.0 COG1562@1|root,COG1562@2|Bacteria,1TQHF@1239|Firmicutes,4HA1A@91061|Bacilli,26H60@186818|Planococcaceae 91061|Bacilli I Squalene/phytoene synthase crtM - 2.5.1.32,2.5.1.99 ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 M00097 R02065,R04218,R07270,R10177 RC00362,RC01101,RC02869 ko00000,ko00001,ko00002,ko01000,ko01006 - - - SQS_PSY k141_29065_2 1307436.PBF_10647 7.4e-58 192.0 COG1233@1|root,COG1233@2|Bacteria,1TRN1@1239|Firmicutes,4HA5W@91061|Bacilli,1ZDED@1386|Bacillus 91061|Bacilli Q Flavin containing amine oxidoreductase - - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 ko:K10027 ko00906,ko01100,ko01110,map00906,map01100,map01110 - R04787,R04798,R04800,R09691,R09692 RC01214,RC02088,RC02605 ko00000,ko00001,ko01000 - - - Amino_oxidase k141_37365_2 1116375.VEJY3_10165 4.79e-259 714.0 COG1058@1|root,COG1058@2|Bacteria,1QUB2@1224|Proteobacteria,1RNXG@1236|Gammaproteobacteria,1XSVF@135623|Vibrionales 135623|Vibrionales S Belongs to the CinA family yfaY - - - - - - - - - - - MoCF_biosynth k141_4181_1 223926.28805851 5.79e-212 599.0 COG1199@1|root,COG1199@2|Bacteria,1MVCU@1224|Proteobacteria,1RMNX@1236|Gammaproteobacteria,1XSPF@135623|Vibrionales 135623|Vibrionales KL ATP-dependent helicase yoaA - 3.6.4.12 ko:K03722 - - - - ko00000,ko01000,ko03400 - - - DEAD,DEAD_2,Helicase_C_2,ResIII k141_4181_2 1116375.VEJY3_03945 9.2e-150 423.0 COG1214@1|root,COG1214@2|Bacteria,1MXPH@1224|Proteobacteria,1RPYX@1236|Gammaproteobacteria,1XTAV@135623|Vibrionales 135623|Vibrionales O COG1214 Inactive homolog of metal-dependent proteases tsaB - - ko:K14742 - - - - ko00000,ko03016 - - - Peptidase_M22 k141_4181_3 223926.28805854 1.19e-54 172.0 2AWHA@1|root,31NDU@2|Bacteria,1QK4W@1224|Proteobacteria,1TI80@1236|Gammaproteobacteria,1XYKX@135623|Vibrionales 135623|Vibrionales - - VV1050 - - - - - - - - - - - - k141_4181_4 1280001.BAOA01000047_gene1748 7.23e-112 323.0 COG3065@1|root,COG3065@2|Bacteria,1MZ8C@1224|Proteobacteria,1S9UB@1236|Gammaproteobacteria,1XX72@135623|Vibrionales 135623|Vibrionales M COG3065 Starvation-inducible outer membrane lipoprotein - - - ko:K07285 - - - - ko00000 - - - Slp k141_2897_1 218284.CCDN010000004_gene3157 2.46e-123 364.0 COG0635@1|root,COG0635@2|Bacteria,1TREM@1239|Firmicutes,4HC2D@91061|Bacilli,1ZCRB@1386|Bacillus 91061|Bacilli H coproporphyrinogen III oxidase hemZ - - - - - - - - - - - Radical_SAM k141_25663_1 1279017.AQYJ01000028_gene2209 3e-186 542.0 COG3008@1|root,COG3008@2|Bacteria,1MU1T@1224|Proteobacteria,1RN89@1236|Gammaproteobacteria,46474@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Paraquat-inducible protein B yebT GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006869,GO:0008150,GO:0009987,GO:0010876,GO:0016020,GO:0016021,GO:0016043,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0033036,GO:0042597,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071840,GO:0071944,GO:0120009 - ko:K06192 - - - - ko00000 - - - MlaD k141_8981_1 796606.BMMGA3_08025 8.55e-91 277.0 COG4585@1|root,COG4585@2|Bacteria,1TSUE@1239|Firmicutes,4HB9N@91061|Bacilli,1ZBZR@1386|Bacillus 91061|Bacilli T Histidine kinase desK GO:0003674,GO:0003824,GO:0004721,GO:0005488,GO:0005515,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0036211,GO:0042578,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 2.7.13.3 ko:K07778 ko02020,map02020 M00479 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA_3 k141_8981_3 218284.CCDN010000001_gene1445 4.67e-52 171.0 COG0819@1|root,COG0819@2|Bacteria,1TPK0@1239|Firmicutes,4HCPF@91061|Bacilli,1ZQWS@1386|Bacillus 91061|Bacilli K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway tenA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 3.5.99.2 ko:K03707 ko00730,ko01100,map00730,map01100 - R02133,R09993 RC00224,RC00652,RC02832 ko00000,ko00001,ko01000,ko03000 - - - TENA_THI-4 k141_1689_1 1123033.ARNF01000042_gene1513 1.42e-14 77.4 COG1266@1|root,COG1266@2|Bacteria,1QPQ0@1224|Proteobacteria,1S8GA@1236|Gammaproteobacteria,3NNXK@468|Moraxellaceae 1236|Gammaproteobacteria S CAAX protease self-immunity - - - ko:K07052 - - - - ko00000 - - - Abi k141_13840_2 218284.CCDN010000005_gene3229 9.64e-133 411.0 COG1074@1|root,COG1074@2|Bacteria,1TQ35@1239|Firmicutes,4HA64@91061|Bacilli,1ZBG6@1386|Bacillus 91061|Bacilli L ATP-dependent helicase nuclease subunit A addA GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 3.6.4.12 ko:K16898 - - - - ko00000,ko01000,ko03400 - - - PDDEXK_1,UvrD-helicase,UvrD_C k141_4203_1 909943.HIMB100_00009070 1.16e-30 125.0 COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,2USBB@28211|Alphaproteobacteria,4BP6U@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria M PFAM Penicillin binding protein transpeptidase domain mrcA - 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - PCB_OB,Transgly,Transpeptidase k141_14797_2 1307436.PBF_15249 6.74e-09 56.6 2CC31@1|root,2Z920@2|Bacteria,1UZSZ@1239|Firmicutes,4HCVB@91061|Bacilli,1ZGJ7@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_16045_2 1116375.VEJY3_17856 3.83e-25 99.0 COG0716@1|root,COG0716@2|Bacteria,1N002@1224|Proteobacteria,1S98G@1236|Gammaproteobacteria,1Y0G5@135623|Vibrionales 135623|Vibrionales C Flavodoxin - - - - - - - - - - - - Flavodoxin_4 k141_1700_1 1175654.A0A0S0N2K6_9CAUD 3.66e-12 67.0 4QBSJ@10239|Viruses,4QXH4@35237|dsDNA viruses no RNA stage,4QPFJ@28883|Caudovirales,4QKUK@10699|Siphoviridae 10699|Siphoviridae S DNA primase activity - - - - - - - - - - - - - k141_1700_2 1175654.A0A0S0NAG1_9CAUD 4.59e-24 97.4 4QAQV@10239|Viruses,4QUPK@35237|dsDNA viruses no RNA stage,4QPCB@28883|Caudovirales 28883|Caudovirales S protein disulfide oxidoreductase activity - - - - - - - - - - - - - k141_1700_5 1175654.A0A0S0MVL0_9CAUD 1.3e-36 130.0 4QANQ@10239|Viruses,4QVSN@35237|dsDNA viruses no RNA stage,4QSEW@28883|Caudovirales,4QMIA@10699|Siphoviridae 10699|Siphoviridae S RNase H - - - - - - - - - - - - - k141_1700_6 706191.PANA_3114 5.86e-129 374.0 COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria,1RPYV@1236|Gammaproteobacteria,3VY3K@53335|Pantoea 1236|Gammaproteobacteria F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis thyA GO:0000287,GO:0003674,GO:0003824,GO:0004799,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006231,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009157,GO:0009162,GO:0009165,GO:0009176,GO:0009177,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009314,GO:0009394,GO:0009628,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0032259,GO:0034641,GO:0034654,GO:0042083,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046073,GO:0046385,GO:0046483,GO:0046872,GO:0050896,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b2827,iAPECO1_1312.APECO1_3678,iBWG_1329.BWG_2562,iE2348C_1286.E2348C_3096,iEC042_1314.EC042_3024,iEC55989_1330.EC55989_3103,iECABU_c1320.ECABU_c31240,iECDH10B_1368.ECDH10B_2997,iECDH1ME8569_1439.ECDH1ME8569_2734,iECED1_1282.ECED1_3283,iECH74115_1262.ECH74115_4093,iECIAI1_1343.ECIAI1_2935,iECIAI39_1322.ECIAI39_3246,iECNA114_1301.ECNA114_2885,iECO103_1326.ECO103_3386,iECO111_1330.ECO111_3555,iECO26_1355.ECO26_3899,iECOK1_1307.ECOK1_3231,iECP_1309.ECP_2840,iECS88_1305.ECS88_3122,iECSE_1348.ECSE_3084,iECSF_1327.ECSF_2642,iECSP_1301.ECSP_3779,iECUMN_1333.ECUMN_3154,iECW_1372.ECW_m3069,iECs_1301.ECs3684,iEKO11_1354.EKO11_0914,iETEC_1333.ETEC_3014,iEcDH1_1363.EcDH1_0864,iEcE24377_1341.EcE24377A_3147,iEcSMS35_1347.EcSMS35_2974,iG2583_1286.G2583_3481,iJO1366.b2827,iJR904.b2827,iLF82_1304.LF82_2267,iNRG857_1313.NRG857_13965,iSSON_1240.SSON_2984,iUMN146_1321.UM146_02290,iUMNK88_1353.UMNK88_3511,iUTI89_1310.UTI89_C3229,iWFL_1372.ECW_m3069,iY75_1357.Y75_RS14705,iYL1228.KPN_03236,iZ_1308.Z4144,ic_1306.c3422 Thymidylat_synt k141_1700_8 1175654.A0A0S0NAE1_9CAUD 7.38e-44 157.0 4QB0T@10239|Viruses,4QV4X@35237|dsDNA viruses no RNA stage,4QPUT@28883|Caudovirales,4QKQK@10699|Siphoviridae 10699|Siphoviridae S Protein of unknown function (DUF669) - - - - - - - - - - - - - k141_1700_9 1175654.A0A0S0NDG6_9CAUD 2.22e-125 368.0 4QDKA@10239|Viruses,4QUPP@35237|dsDNA viruses no RNA stage,4QPPG@28883|Caudovirales,4QMZH@10699|Siphoviridae 10699|Siphoviridae S nuclease activity - - - - - - - - - - - - - k141_1700_11 1175654.A0A0S0MVP1_9CAUD 6.43e-225 641.0 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales,4QKRP@10699|Siphoviridae 10699|Siphoviridae S helicase activity - - - - - - - - - - - - - k141_25696_1 1121921.KB898709_gene88 4.4e-18 85.9 COG3507@1|root,COG3507@2|Bacteria,1NNX4@1224|Proteobacteria,1RYTM@1236|Gammaproteobacteria,2PNIB@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria G Glycosyl hydrolases family 43 - - 3.2.1.37,3.2.1.55 ko:K01198,ko:K01209 ko00520,ko01100,map00520,map01100 - R01433,R01762 RC00467 ko00000,ko00001,ko01000 - GH43,GH51 - Glyco_hydro_43 k141_25696_2 983545.Glaag_3720 4.03e-40 139.0 COG1051@1|root,COG1051@2|Bacteria,1QTT4@1224|Proteobacteria,1RQ35@1236|Gammaproteobacteria,466MF@72275|Alteromonadaceae 1236|Gammaproteobacteria F NUDIX domain nuhA - - - - - - - - - - - NUDIX k141_8987_1 1196323.ALKF01000134_gene3381 3.2e-19 87.8 COG3459@1|root,COG3459@2|Bacteria,1TVMK@1239|Firmicutes,4H9ZP@91061|Bacilli,26RDW@186822|Paenibacillaceae 91061|Bacilli G Cellobiose phosphorylase chvB1 - 2.4.1.20,2.4.1.333 ko:K00702,ko:K13688,ko:K21298 ko00500,ko01100,map00500,map01100 - R00952 RC00049 ko00000,ko00001,ko01000,ko01003 - GH94,GT36,GT84 - Glyco_hydro_36,Glyco_transf_36 k141_8987_2 1121090.KB894685_gene3428 9.34e-41 138.0 COG3663@1|root,COG3663@2|Bacteria,1V3X9@1239|Firmicutes,4HHMZ@91061|Bacilli,1ZFP1@1386|Bacillus 91061|Bacilli L COG3663 G T U mismatch-specific DNA glycosylase - - 3.2.2.28 ko:K03649 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG k141_32552_1 218284.CCDN010000001_gene750 3.05e-54 173.0 COG0319@1|root,COG0319@2|Bacteria,1V6BU@1239|Firmicutes,4HIIE@91061|Bacilli,1ZG7I@1386|Bacillus 91061|Bacilli S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ybeY - - ko:K07042 - - - - ko00000,ko03009 - - - UPF0054 k141_32552_2 218284.CCDN010000001_gene749 7.41e-36 135.0 COG1480@1|root,COG1480@2|Bacteria,1TR1A@1239|Firmicutes,4HAEZ@91061|Bacilli,1ZANS@1386|Bacillus 91061|Bacilli S membrane-associated HD superfamily hydrolase yqfF - - ko:K07037 - - - - ko00000 - - - 7TM-7TMR_HD,7TMR-HDED,HD k141_10256_2 218284.CCDN010000006_gene3614 7.37e-18 80.1 COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,4HAPT@91061|Bacilli,1ZB6N@1386|Bacillus 91061|Bacilli G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) tpiA GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01015 RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 - - - TIM k141_21994_1 1294265.JCM21738_1730 3.44e-81 271.0 COG1404@1|root,COG1520@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria,1TPUY@1239|Firmicutes,4HBDE@91061|Bacilli,1ZDEQ@1386|Bacillus 91061|Bacilli O COG1404 Subtilisin-like serine proteases - - - - - - - - - - - - CarbopepD_reg_2,CarboxypepD_reg,Peptidase_S8 k141_13869_1 1279017.AQYJ01000029_gene3816 6.61e-85 267.0 COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,1RN5K@1236|Gammaproteobacteria,466GP@72275|Alteromonadaceae 1236|Gammaproteobacteria MU Outer membrane efflux protein lprN - - - - - - - - - - - OEP k141_24337_1 926569.ANT_13370 1.56e-85 267.0 COG0464@1|root,COG0464@2|Bacteria,2G642@200795|Chloroflexi 200795|Chloroflexi O SMART AAA ATPase - - - - - - - - - - - - AAA k141_17207_1 218284.CCDN010000002_gene2609 3.34e-55 185.0 COG1173@1|root,COG1173@2|Bacteria,1V21B@1239|Firmicutes,4HJ5Y@91061|Bacilli,1ZFPK@1386|Bacillus 91061|Bacilli EP ABC transporter (permease) - - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 k141_14798_1 45130.XP_007705856.1 4.02e-34 130.0 COG2355@1|root,KOG4127@2759|Eukaryota,38D9H@33154|Opisthokonta,3NUTJ@4751|Fungi,3QKPA@4890|Ascomycota,204F2@147541|Dothideomycetes,4KHM4@92860|Pleosporales 4751|Fungi O Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family - GO:0008150,GO:0008152,GO:0009058,GO:0009403,GO:0009404,GO:0009987,GO:0019748,GO:0043385,GO:0043386,GO:0044237,GO:0044249,GO:0044550 3.4.13.19 ko:K01273 - - - - ko00000,ko00537,ko01000,ko01002,ko04147 - - - Peptidase_M19 k141_19667_1 370438.PTH_1387 5.01e-66 226.0 COG1615@1|root,COG1615@2|Bacteria,1TQHM@1239|Firmicutes,248PM@186801|Clostridia,260EY@186807|Peptococcaceae 186801|Clostridia S PFAM Uncharacterised protein family UPF0182 - - - ko:K09118 - - - - ko00000 - - - UPF0182 k141_16046_1 867903.ThesuDRAFT_02300 6.06e-21 91.3 COG0533@1|root,COG0533@2|Bacteria,1TQDR@1239|Firmicutes,247MG@186801|Clostridia,3WCCE@538999|Clostridiales incertae sedis 186801|Clostridia O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction tsaD - 2.3.1.234 ko:K01409 - - R10648 RC00070,RC00416 ko00000,ko01000,ko03016 - - - Peptidase_M22 k141_10257_1 1347087.CBYO010000020_gene3035 8.03e-95 281.0 COG2019@1|root,COG2019@2|Bacteria,1V6Q3@1239|Firmicutes,4HK46@91061|Bacilli 91061|Bacilli F adenylate kinase activity - - - - - - - - - - - - AAA_18 k141_36146_3 1279017.AQYJ01000027_gene1909 1.58e-47 163.0 COG2177@1|root,COG2177@2|Bacteria,1MU65@1224|Proteobacteria,1RYBV@1236|Gammaproteobacteria,464N0@72275|Alteromonadaceae 1236|Gammaproteobacteria D Part of the ABC transporter FtsEX involved in cellular division ftsX GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0009274,GO:0009276,GO:0009987,GO:0016020,GO:0016021,GO:0030312,GO:0030313,GO:0031224,GO:0031975,GO:0032153,GO:0044425,GO:0044464,GO:0051301,GO:0071944 - ko:K09811 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - FtsX k141_24338_1 1279017.AQYJ01000024_gene975 3.48e-66 216.0 COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,1RM8M@1236|Gammaproteobacteria,46473@72275|Alteromonadaceae 1236|Gammaproteobacteria M Transfers the fatty acyl group on membrane lipoproteins lnt GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016021,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031224,GO:0031226,GO:0034645,GO:0036211,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576 - ko:K03820 - - - - ko00000,ko01000 - GT2 iEcSMS35_1347.EcSMS35_0678,iSbBS512_1146.SbBS512_E0590 CN_hydrolase k141_33909_1 314265.R2601_05593 4.53e-99 296.0 COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,2TSBK@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Responsible for synthesis of pseudouridine from uracil rluD GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 ko:K06180 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 k141_14799_1 469383.Cwoe_0844 3.85e-61 197.0 COG1250@1|root,COG1250@2|Bacteria,2GJBM@201174|Actinobacteria,4CQ21@84995|Rubrobacteria 84995|Rubrobacteria I 3-hydroxyacyl-CoA dehydrogenase - - 1.1.1.157 ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 - R01976,R05576,R06941 RC00029,RC00117 ko00000,ko00001,ko01000 - - - 3HCDH,3HCDH_N k141_2915_1 1042377.AFPJ01000055_gene980 1.33e-32 115.0 COG3139@1|root,COG3139@2|Bacteria,1N7ZT@1224|Proteobacteria,1SC7K@1236|Gammaproteobacteria,4696A@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF1315) - - - ko:K09916 - - - - ko00000 - - - DUF1315 k141_32554_1 861299.J421_2201 4.52e-46 167.0 COG0591@1|root,COG0591@2|Bacteria,1ZT5V@142182|Gemmatimonadetes 142182|Gemmatimonadetes E Sodium:solute symporter family - - - - - - - - - - - - SSF k141_8990_1 1121106.JQKB01000106_gene6026 6.41e-11 63.9 COG3734@1|root,COG3734@2|Bacteria,1MWGX@1224|Proteobacteria,2TTG8@28211|Alphaproteobacteria,2JSCZ@204441|Rhodospirillales 204441|Rhodospirillales G 2-keto-3-deoxy-galactonokinase dgoK - 2.7.1.58 ko:K00883 ko00052,ko01100,map00052,map01100 M00552 R03387 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - DGOK k141_8990_2 272943.RSP_1369 1.77e-28 109.0 COG1028@1|root,COG1028@2|Bacteria,1MXTP@1224|Proteobacteria,2TQST@28211|Alphaproteobacteria,1FCNX@1060|Rhodobacter 28211|Alphaproteobacteria IQ Short-chain dehydrogenase reductase SDR - - 1.1.1.120,1.1.1.175,1.1.1.48 ko:K22185,ko:K22215 ko00040,ko00052,ko01100,map00040,map00052,map01100 - R01094,R01097,R01429 RC00066,RC00161 ko00000,ko00001,ko01000 - - - adh_short_C2 k141_742_1 1042377.AFPJ01000036_gene1185 4.84e-115 340.0 COG3199@1|root,COG3199@2|Bacteria,1MY3J@1224|Proteobacteria,1RP9X@1236|Gammaproteobacteria,464PX@72275|Alteromonadaceae 1236|Gammaproteobacteria S Diacylglycerol kinase catalytic domain - - - - - - - - - - - - NAD_kinase k141_24339_1 1453501.JELR01000001_gene2104 2.54e-45 160.0 COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RP53@1236|Gammaproteobacteria,466MR@72275|Alteromonadaceae 1236|Gammaproteobacteria T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg k141_13871_1 1294265.JCM21738_3314 9.96e-150 423.0 COG1381@1|root,COG1381@2|Bacteria,1UZ19@1239|Firmicutes,4HAHI@91061|Bacilli,1ZAUA@1386|Bacillus 91061|Bacilli L Involved in DNA repair and RecF pathway recombination recO GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - ko:K03584 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecO_C,RecO_N k141_29083_1 1279017.AQYJ01000028_gene2502 5.42e-83 251.0 COG0576@1|root,COG0576@2|Bacteria,1RH8T@1224|Proteobacteria,1S5W5@1236|Gammaproteobacteria,467BX@72275|Alteromonadaceae 1236|Gammaproteobacteria O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ grpE GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0017076,GO:0019904,GO:0022607,GO:0030234,GO:0030554,GO:0032991,GO:0036094,GO:0042802,GO:0042803,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0050790,GO:0050896,GO:0051082,GO:0060589,GO:0060590,GO:0065003,GO:0065007,GO:0065009,GO:0071840,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - ko:K03687 - - - - ko00000,ko03029,ko03110 - - - GrpE k141_29083_2 1453501.JELR01000002_gene433 0.0 1061.0 COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,1RMDD@1236|Gammaproteobacteria,4644X@72275|Alteromonadaceae 1236|Gammaproteobacteria O Heat shock 70 kDa protein dnaK GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 - - HSP70 k141_35140_1 1116375.VEJY3_13550 2.04e-243 676.0 COG4325@1|root,COG4325@2|Bacteria,1MXTM@1224|Proteobacteria,1RNYZ@1236|Gammaproteobacteria,1XWKN@135623|Vibrionales 135623|Vibrionales S Predicted membrane protein (DUF2254) - - - - - - - - - - - - DUF2254 k141_35140_2 1116375.VEJY3_13555 1.8e-97 285.0 COG1714@1|root,COG1714@2|Bacteria,1N4N8@1224|Proteobacteria,1S9C5@1236|Gammaproteobacteria,1XVQP@135623|Vibrionales 135623|Vibrionales S membrane protein domain VP2641 - - - - - - - - - - - RDD k141_12679_2 1279017.AQYJ01000029_gene3432 2.61e-63 209.0 COG3106@1|root,COG3106@2|Bacteria,1MX6E@1224|Proteobacteria,1RQ05@1236|Gammaproteobacteria,464CF@72275|Alteromonadaceae 1236|Gammaproteobacteria S YcjX-like family, DUF463 ycjX - - ko:K06918 - - - - ko00000 - - - DUF463 k141_21996_1 935836.JAEL01000068_gene1763 4.49e-97 293.0 COG2223@1|root,COG2223@2|Bacteria,1TPR9@1239|Firmicutes,4HB93@91061|Bacilli,1ZAP4@1386|Bacillus 91061|Bacilli P Major facilitator superfamily oxlT - - ko:K08177 - - - - ko00000,ko02000 2.A.1.11 - - MFS_1 k141_29285_2 218284.CCDN010000002_gene2773 2.22e-27 100.0 29S6P@1|root,30DB7@2|Bacteria,1UB3N@1239|Firmicutes,4IMG9@91061|Bacilli,1ZK3B@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_29285_3 935837.JAEK01000040_gene3712 3.52e-23 89.4 COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,4HNJC@91061|Bacilli,1ZHSU@1386|Bacillus 91061|Bacilli K Cold shock - - - ko:K03704 - - - - ko00000,ko03000 - - - CSD k141_6798_1 1279017.AQYJ01000018_gene827 3.46e-114 369.0 COG0770@1|root,COG2843@1|root,COG0770@2|Bacteria,COG2843@2|Bacteria,1QTSF@1224|Proteobacteria,1RMGD@1236|Gammaproteobacteria,464UU@72275|Alteromonadaceae 1236|Gammaproteobacteria M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein - - - - - - - - - - - - Mur_ligase_C,Mur_ligase_M,PGA_cap k141_14135_1 1196031.ALEG01000039_gene1776 7.33e-75 233.0 COG1638@1|root,COG1638@2|Bacteria,1TP3I@1239|Firmicutes,4HD0U@91061|Bacilli,1ZCY6@1386|Bacillus 91061|Bacilli G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component - - - - - - - - - - - - DctP k141_14135_2 665959.HMPREF1013_00155 3.46e-44 148.0 COG3090@1|root,COG3090@2|Bacteria 2|Bacteria G Trap-type c4-dicarboxylate transport system, small permease component - - - ko:K11689 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.56.1 - - DctQ k141_19855_1 1294265.JCM21738_1908 1.34e-60 192.0 COG0623@1|root,COG0623@2|Bacteria,1TPVD@1239|Firmicutes,4H9YN@91061|Bacilli,1ZAP0@1386|Bacillus 91061|Bacilli I Enoyl- acyl-carrier-protein reductase NADH fabI GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006950,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0033554,GO:0036094,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051716,GO:0055114,GO:0065003,GO:0070417,GO:0071704,GO:0071840,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.3.1.10,1.3.1.9 ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 M00083,M00572 R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671 RC00052,RC00076,RC00120 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 k141_23583_1 1211814.CAPG01000027_gene1291 5.29e-32 126.0 COG1674@1|root,COG1674@2|Bacteria,1TWB0@1239|Firmicutes,4HCGJ@91061|Bacilli,1ZD0W@1386|Bacillus 91061|Bacilli D FtsK/SpoIIIE family - - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_SpoIIIE k141_30317_1 218284.CCDN010000005_gene3312 8.44e-106 310.0 COG2323@1|root,COG2323@2|Bacteria,1TRWQ@1239|Firmicutes,4H9VA@91061|Bacilli,1ZCPH@1386|Bacillus 91061|Bacilli S membrane - - - - - - - - - - - - DUF1657,DUF421 k141_18836_1 1449049.JONW01000005_gene1160 2.22e-75 235.0 COG2850@1|root,COG2850@2|Bacteria,1MUAC@1224|Proteobacteria,2TSG2@28211|Alphaproteobacteria,2KHVD@204458|Caulobacterales 204458|Caulobacterales S transcription factor jumonji - - - - - - - - - - - - Cupin_8 k141_36293_1 309801.trd_1027 4.11e-17 83.2 COG0142@1|root,COG0142@2|Bacteria,2G6IZ@200795|Chloroflexi,27XMM@189775|Thermomicrobia 189775|Thermomicrobia H Belongs to the FPP GGPP synthase family - - 2.5.1.90 ko:K02523 ko00900,ko01110,map00900,map01110 - R09248 RC00279 ko00000,ko00001,ko01000,ko01006 - - - polyprenyl_synt k141_14156_1 448385.sce6169 7.23e-05 45.1 COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,42M67@68525|delta/epsilon subdivisions,2WJQX@28221|Deltaproteobacteria,2YTX6@29|Myxococcales 28221|Deltaproteobacteria E Cys Met metabolism metC - 2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.8 ko:K01739,ko:K01758,ko:K01760,ko:K01761 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017,M00338 R00654,R00782,R00999,R01001,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04941,R04944,R04945,R04946,R09366 RC00020,RC00056,RC00069,RC00196,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Cys_Met_Meta_PP k141_14156_2 218284.CCDN010000008_gene4260 2.83e-93 274.0 COG1956@1|root,COG1956@2|Bacteria,1V6GQ@1239|Firmicutes,4HH7X@91061|Bacilli,1ZFMG@1386|Bacillus 91061|Bacilli T GAF domain-containing protein ytsP - 1.8.4.14 ko:K08968 ko00270,map00270 - R02025 RC00639 ko00000,ko00001,ko01000 - - - GAF_2 k141_7890_1 1453501.JELR01000002_gene1489 4.62e-258 729.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MUNK@1224|Proteobacteria,1RN9S@1236|Gammaproteobacteria,469NI@72275|Alteromonadaceae 1236|Gammaproteobacteria P receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_34100_2 1279017.AQYJ01000024_gene988 0.0 899.0 COG0129@1|root,COG0129@2|Bacteria,1MU3T@1224|Proteobacteria,1RMNA@1236|Gammaproteobacteria,464QM@72275|Alteromonadaceae 1236|Gammaproteobacteria EG Belongs to the IlvD Edd family edd GO:0003674,GO:0003824,GO:0004456,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019520,GO:0019521,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0046176,GO:0046177,GO:0046395,GO:0071704,GO:0072329,GO:1901575 4.2.1.12 ko:K01690 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 M00008 R02036 RC00543 ko00000,ko00001,ko00002,ko01000 - - iEcolC_1368.EcolC_1781,iJN746.PP_1010,iPC815.YPO2533,iYL1228.KPN_02366 ILVD_EDD k141_12858_1 265729.GS18_0215920 1.14e-35 136.0 COG0697@1|root,COG0697@2|Bacteria,1TSX6@1239|Firmicutes,4HCV4@91061|Bacilli,1ZCUJ@1386|Bacillus 91061|Bacilli EG Bacillus/Clostridium GerA spore germination protein - - - - - - - - - - - - GerA k141_32790_1 218284.CCDN010000001_gene1898 6.22e-21 89.0 COG0020@1|root,COG0020@2|Bacteria,1TQTS@1239|Firmicutes,4HA37@91061|Bacilli,1ZC2T@1386|Bacillus 91061|Bacilli I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids uppS GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 ko:K00806 ko00900,ko01110,map00900,map01110 - R06447 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 - - - Prenyltransf k141_35363_1 1132442.KB889752_gene2729 5.98e-98 298.0 COG1524@1|root,COG1524@2|Bacteria,1UY6W@1239|Firmicutes,4HDR4@91061|Bacilli,1ZDAM@1386|Bacillus 91061|Bacilli S Type I phosphodiesterase / nucleotide pyrophosphatase - - - - - - - - - - - - Phosphodiest k141_22257_1 218284.CCDN010000001_gene28 9.34e-105 310.0 COG0331@1|root,COG0331@2|Bacteria,1TPB7@1239|Firmicutes,4HBCU@91061|Bacilli,1ZBGQ@1386|Bacillus 91061|Bacilli I malonyl CoA-acyl carrier protein transacylase fabD - 2.3.1.39 ko:K00645 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082 R01626,R11671 RC00004,RC00039,RC02727 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyl_transf_1 k141_22257_2 218284.CCDN010000001_gene29 5.06e-200 558.0 COG0416@1|root,COG0416@2|Bacteria,1TPXS@1239|Firmicutes,4HA0R@91061|Bacilli,1ZBW8@1386|Bacillus 91061|Bacilli I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA plsX GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.15 ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FA_synthesis k141_3108_1 1294265.JCM21738_3697 2.21e-20 84.7 COG0377@1|root,COG0377@2|Bacteria,1TZS1@1239|Firmicutes,4HACH@91061|Bacilli,1ZDCP@1386|Bacillus 91061|Bacilli C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoB GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 ko:K00331 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q6 k141_3108_2 1294265.JCM21738_3696 3.45e-81 241.0 COG0838@1|root,COG0838@2|Bacteria,1V6P3@1239|Firmicutes,4HIFX@91061|Bacilli,1ZGE2@1386|Bacillus 91061|Bacilli C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoA GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 ko:K00330 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q4 k141_6818_1 1283300.ATXB01000001_gene1129 7.7e-89 273.0 COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,1RN1G@1236|Gammaproteobacteria 1236|Gammaproteobacteria E belongs to the aspartokinase family thrA GO:0003674,GO:0003824,GO:0004072,GO:0004412,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009085,GO:0009089,GO:0009090,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.3,2.7.2.4 ko:K12524,ko:K12525 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00017,M00018,M00526,M00527 R00480,R01773,R01775 RC00002,RC00043,RC00087 ko00000,ko00001,ko00002,ko01000 - - iECDH1ME8569_1439.ECDH1ME8569_0002,iEcDH1_1363.EcDH1_3594,iSFV_1184.SFV_0001,iUMNK88_1353.UMNK88_4778,iYL1228.KPN_04234 AA_kinase,ACT,ACT_7,Homoserine_dh,NAD_binding_3 k141_12859_1 43151.ADAC004972-PA 1.16e-34 133.0 COG3483@1|root,KOG3906@2759|Eukaryota,38BTM@33154|Opisthokonta,3BB71@33208|Metazoa,3CUF5@33213|Bilateria,41W0Q@6656|Arthropoda,3SH4N@50557|Insecta,450TT@7147|Diptera,45BII@7148|Nematocera 33208|Metazoa E Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety TDO2 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006084,GO:0006139,GO:0006163,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006637,GO:0006725,GO:0006726,GO:0006727,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008055,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009063,GO:0009072,GO:0009074,GO:0009117,GO:0009150,GO:0009259,GO:0009308,GO:0009310,GO:0009987,GO:0010941,GO:0010942,GO:0016043,GO:0016054,GO:0016491,GO:0016597,GO:0016701,GO:0016702,GO:0018130,GO:0019438,GO:0019439,GO:0019441,GO:0019442,GO:0019637,GO:0019693,GO:0019748,GO:0019752,GO:0019825,GO:0020037,GO:0022607,GO:0031406,GO:0033060,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0036094,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042440,GO:0042441,GO:0042537,GO:0042802,GO:0043167,GO:0043168,GO:0043177,GO:0043324,GO:0043436,GO:0043473,GO:0043474,GO:0043603,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0046148,GO:0046152,GO:0046158,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0048066,GO:0048069,GO:0048072,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051186,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0055114,GO:0065003,GO:0065007,GO:0070189,GO:0071704,GO:0071840,GO:0072521,GO:0097159,GO:1901135,GO:1901214,GO:1901216,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901605,GO:1901606 1.13.11.11 ko:K00453 ko00380,ko01100,map00380,map01100 M00038 R00678 RC00356 ko00000,ko00001,ko00002,ko01000 - - - Trp_dioxygenase k141_22258_1 383372.Rcas_3207 5.16e-18 88.6 COG1672@1|root,COG2319@1|root,COG1672@2|Bacteria,COG2319@2|Bacteria,2G8HW@200795|Chloroflexi,376W0@32061|Chloroflexia 32061|Chloroflexia S WD40 repeats - - - - - - - - - - - - WD40 k141_34101_1 1285586.H131_12283 1.95e-55 185.0 COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,4HAE3@91061|Bacilli,3IXB8@400634|Lysinibacillus 91061|Bacilli E ABC transporter braC - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 k141_30318_1 1453501.JELR01000002_gene1489 4.99e-87 279.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MUNK@1224|Proteobacteria,1RN9S@1236|Gammaproteobacteria,469NI@72275|Alteromonadaceae 1236|Gammaproteobacteria P receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_37512_2 1279017.AQYJ01000024_gene925 3.48e-135 386.0 COG0321@1|root,COG0321@2|Bacteria,1MU6A@1224|Proteobacteria,1RMXQ@1236|Gammaproteobacteria,466J6@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate lipB GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0016874,GO:0016879,GO:0016979,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019222,GO:0019538,GO:0019752,GO:0032787,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048519,GO:0050789,GO:0051186,GO:0051188,GO:0051604,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0140096,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.3.1.181 ko:K03801 ko00785,ko01100,map00785,map01100 - R07766,R07769 RC00039,RC00992,RC02867 ko00000,ko00001,ko01000 - - iECSF_1327.ECSF_0569,iSFV_1184.SFV_0696,iSFxv_1172.SFxv_0718 BPL_LplA_LipB k141_37512_3 1279017.AQYJ01000024_gene924 1.65e-25 96.3 COG2921@1|root,COG2921@2|Bacteria,1PJDV@1224|Proteobacteria,1SXYT@1236|Gammaproteobacteria,468E1@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the UPF0250 family - - - ko:K09158 - - - - ko00000 - - - DUF493 k141_31479_1 223926.28807696 1.08e-25 105.0 COG3164@1|root,COG3164@2|Bacteria,1MXWF@1224|Proteobacteria,1RNUK@1236|Gammaproteobacteria,1XTHT@135623|Vibrionales 135623|Vibrionales S Protein of unknown function VV2929 - - - - - - - - - - - AsmA_2,DUF3971 k141_31479_2 1219076.N646_1776 3.41e-48 161.0 COG0388@1|root,COG0388@2|Bacteria,1MUUB@1224|Proteobacteria,1RNVZ@1236|Gammaproteobacteria,1XSQV@135623|Vibrionales 135623|Vibrionales S Carbon-nitrogen hydrolase - - - ko:K11206 - - - - ko00000,ko01000 - - - CN_hydrolase k141_16234_1 1453501.JELR01000002_gene1011 1.8e-60 202.0 COG3540@1|root,COG3540@2|Bacteria,1MWAF@1224|Proteobacteria,1RNY4@1236|Gammaproteobacteria,464EY@72275|Alteromonadaceae 1236|Gammaproteobacteria P alkaline phosphatase phoD - 3.1.3.1 ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 M00126 R04620 RC00017 ko00000,ko00001,ko00002,ko01000 - - - PhoD,PhoD_N k141_4322_2 1279017.AQYJ01000023_gene3275 4.39e-144 419.0 COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,1RNPX@1236|Gammaproteobacteria,464Y1@72275|Alteromonadaceae 1236|Gammaproteobacteria P Belongs to the ABC transporter superfamily fbpC - 3.6.3.30 ko:K02010 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.10 - - ABC_tran,TOBE_2 k141_32791_1 1196028.ALEF01000004_gene3385 2.1e-34 132.0 COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,4H9T1@91061|Bacilli,4C4K7@84406|Virgibacillus 91061|Bacilli M acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan - - 6.3.2.13 ko:K01928 ko00300,ko00550,map00300,map00550 - R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M k141_23586_2 218284.CCDN010000002_gene2119 4.52e-86 255.0 COG0440@1|root,COG0440@2|Bacteria,1V2AJ@1239|Firmicutes,4HDY5@91061|Bacilli,1ZFP3@1386|Bacillus 91061|Bacilli E Acetolactate synthase ilvN GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 M00019,M00570,M00582 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ACT,ACT_5,ALS_ss_C k141_27264_2 1042377.AFPJ01000036_gene1136 2.21e-210 600.0 COG0654@1|root,COG0654@2|Bacteria,1NSGN@1224|Proteobacteria,1T22A@1236|Gammaproteobacteria,46505@72275|Alteromonadaceae 1236|Gammaproteobacteria CH Tryptophan halogenase - - - - - - - - - - - - Trp_halogenase k141_27264_3 1042377.AFPJ01000036_gene1135 2.95e-234 660.0 COG0665@1|root,COG0665@2|Bacteria,1MU40@1224|Proteobacteria,1RMJY@1236|Gammaproteobacteria,463ZR@72275|Alteromonadaceae 1236|Gammaproteobacteria E Tryptophan halogenase prnA - 1.14.19.9 ko:K14266 ko00404,ko01130,map00404,map01130 M00789,M00790 R09570 RC00949 ko00000,ko00001,ko00002,ko01000 - - - Trp_halogenase k141_15003_1 218284.CCDN010000006_gene3516 1.12e-54 176.0 COG2364@1|root,COG2364@2|Bacteria,1V3NC@1239|Firmicutes,4HGRQ@91061|Bacilli,1ZCBH@1386|Bacillus 91061|Bacilli S Membrane - - - ko:K07149 - - - - ko00000 - - - YitT_membrane k141_5696_1 218284.CCDN010000011_gene4419 3.63e-142 414.0 COG1488@1|root,COG1488@2|Bacteria,1TPDW@1239|Firmicutes,4HAI4@91061|Bacilli,1ZCGY@1386|Bacillus 91061|Bacilli H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP pncB - 6.3.4.21 ko:K00763 ko00760,ko01100,map00760,map01100 - R01724 RC00033 ko00000,ko00001,ko01000 - - iYO844.BSU31750 NAPRTase k141_5696_2 218284.CCDN010000011_gene4420 3.27e-70 219.0 COG0171@1|root,COG0171@2|Bacteria,1TQ38@1239|Firmicutes,4HA2R@91061|Bacilli,1ZBM2@1386|Bacillus 91061|Bacilli H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source nadE GO:0000003,GO:0003674,GO:0003824,GO:0003952,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0016884,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019954,GO:0030436,GO:0032502,GO:0034641,GO:0034654,GO:0043934,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5 ko:K01916 ko00760,ko01100,map00760,map01100 M00115 R00189 RC00100 ko00000,ko00001,ko00002,ko01000 - - - NAD_synthase k141_1870_1 1294265.JCM21738_3748 6.03e-81 245.0 COG0619@1|root,COG0619@2|Bacteria,1TQ0E@1239|Firmicutes,4H9VT@91061|Bacilli,1ZBNS@1386|Bacillus 91061|Bacilli P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates ecfT - - ko:K16785 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - CbiQ k141_1870_2 1294265.JCM21738_3749 9.33e-21 83.2 COG0101@1|root,COG0101@2|Bacteria 2|Bacteria J tRNA pseudouridine synthase activity truA GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 ko:K06173 - - - - ko00000,ko01000,ko03016 - - - PseudoU_synth_1 k141_6820_1 1385514.N782_08280 9.31e-44 152.0 COG1028@1|root,COG1028@2|Bacteria,1TR1J@1239|Firmicutes,4HAQ2@91061|Bacilli,2Y9MU@289201|Pontibacillus 91061|Bacilli IQ 3-ketoacyl-ACP reductase - - - - - - - - - - - - adh_short_C2 k141_27917_1 223926.28809340 1.96e-130 402.0 COG3523@1|root,COG3523@2|Bacteria,1MV3D@1224|Proteobacteria,1RPQ2@1236|Gammaproteobacteria,1XSAX@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria - - - ko:K11891 ko02025,ko03070,map02025,map03070 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - IcmF-related,IcmF_C,ImcF-related_N k141_27917_2 223926.28809339 7.24e-112 327.0 COG3913@1|root,COG3913@2|Bacteria,1N01G@1224|Proteobacteria,1SFIS@1236|Gammaproteobacteria,1XX0Q@135623|Vibrionales 135623|Vibrionales S Uncharacterized protein conserved in bacteria (DUF2094) - - - ko:K11890 ko02025,map02025 - - - ko00000,ko00001,ko02044 - - - DUF2094 k141_27917_3 1219076.N646_4408 1.8e-160 452.0 COG0631@1|root,COG0631@2|Bacteria,1R7UF@1224|Proteobacteria,1S3HA@1236|Gammaproteobacteria,1XWM9@135623|Vibrionales 135623|Vibrionales T Serine/threonine phosphatases, family 2C, catalytic domain - - 3.1.3.16 ko:K20074 - - - - ko00000,ko01000,ko01009 - - - PP2C_2 k141_27917_4 223926.28809337 3.79e-198 557.0 COG3515@1|root,COG3515@2|Bacteria,1MY80@1224|Proteobacteria,1T0A1@1236|Gammaproteobacteria,1Y2IU@135623|Vibrionales 135623|Vibrionales S ImpA, N-terminal, type VI secretion system VPA1036 - - ko:K11902 ko02025,map02025 M00334 - - ko00000,ko00001,ko00002,ko02044 - - - ImpA_N k141_27917_5 223926.28809336 1.87e-105 306.0 COG3516@1|root,COG3516@2|Bacteria,1R9Y7@1224|Proteobacteria,1T190@1236|Gammaproteobacteria,1Y316@135623|Vibrionales 135623|Vibrionales S Type VI secretion system, VipA, VC_A0107 or Hcp2 - - - ko:K11901 ko02025,map02025 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - T6SS_VipA k141_27917_6 223926.28809335 0.0 944.0 COG3517@1|root,COG3517@2|Bacteria,1MU5C@1224|Proteobacteria,1RNP7@1236|Gammaproteobacteria,1XUBM@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria - - - ko:K11900 ko02025,map02025 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - VipB k141_27917_7 223926.28809334 1.51e-261 728.0 COG3517@1|root,COG3517@2|Bacteria,1MU5C@1224|Proteobacteria,1RNP7@1236|Gammaproteobacteria,1XVG6@135623|Vibrionales 135623|Vibrionales S Type VI secretion protein, EvpB/VC_A0108, tail sheath - - - ko:K11899 - - - - ko00000,ko02044 - - - VipB k141_27917_8 223926.28809333 8.69e-134 385.0 COG4455@1|root,COG4455@2|Bacteria,1MWHI@1224|Proteobacteria,1RXYE@1236|Gammaproteobacteria,1XVFU@135623|Vibrionales 135623|Vibrionales S ImpE protein VPA1032 - - ko:K11898 - - - - ko00000,ko02044 - - - ImpE k141_27917_9 1219076.N646_4402 4.96e-72 220.0 COG3518@1|root,COG3518@2|Bacteria,1RG8W@1224|Proteobacteria,1S50E@1236|Gammaproteobacteria,1XXTM@135623|Vibrionales 135623|Vibrionales S Gene 25-like lysozyme - - - ko:K11897 - M00334 - - ko00000,ko00002,ko02044 - - - GPW_gp25 k141_27917_10 674977.VMC_29490 0.0 903.0 COG3519@1|root,COG3519@2|Bacteria,1MUY4@1224|Proteobacteria,1RPK4@1236|Gammaproteobacteria,1XTN2@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria - - - ko:K11896 - M00334 - - ko00000,ko00002,ko02044 3.A.23.1 - - T6SS_TssF k141_27917_11 1219076.N646_4400 7.56e-151 433.0 COG3520@1|root,COG3520@2|Bacteria,1MWVS@1224|Proteobacteria,1RRTG@1236|Gammaproteobacteria,1Y2CU@135623|Vibrionales 135623|Vibrionales S Type VI secretion, TssG - - - ko:K11895 ko02025,map02025 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - T6SS_TssG k141_27917_12 223926.28809329 0.0 1373.0 COG0542@1|root,COG0542@2|Bacteria,1MVBH@1224|Proteobacteria,1RMZH@1236|Gammaproteobacteria,1XTVD@135623|Vibrionales 135623|Vibrionales O Belongs to the ClpA ClpB family - - - ko:K11907 ko02025,ko03070,map02025,map03070 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - AAA,AAA_2,ClpB_D2-small,Clp_N k141_27917_13 223926.28809328 9e-107 308.0 COG3157@1|root,COG3157@2|Bacteria,1RCKW@1224|Proteobacteria,1SYIZ@1236|Gammaproteobacteria,1XVU9@135623|Vibrionales 135623|Vibrionales S Type VI secretion system effector, Hcp VPA1027 - - ko:K11903 ko02025,ko03070,map02025,map03070 M00334 - - ko00000,ko00001,ko00002,ko02044 - - - T6SS_HCP k141_27917_14 1219076.N646_4397 6.08e-289 806.0 COG3501@1|root,COG3501@2|Bacteria,1MU7Q@1224|Proteobacteria,1RMZS@1236|Gammaproteobacteria,1XUHW@135623|Vibrionales 135623|Vibrionales M protein conserved in bacteria - - - ko:K11904 ko03070,map03070 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - Phage_GPD k141_27917_15 223926.28809325 1.11e-80 251.0 2EHXG@1|root,33BP0@2|Bacteria,1NM5H@1224|Proteobacteria,1SHCW@1236|Gammaproteobacteria,1XYTX@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_27917_16 1116375.VEJY3_19376 7.66e-253 696.0 COG0420@1|root,COG0420@2|Bacteria,1MVV6@1224|Proteobacteria,1RP83@1236|Gammaproteobacteria,1XW3R@135623|Vibrionales 135623|Vibrionales L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity sbcD - - ko:K03547 - - - - ko00000,ko03400 - - - Metallophos,SbcD_C k141_27917_17 1116375.VEJY3_19381 0.0 1513.0 COG0419@1|root,COG0419@2|Bacteria,1MVTQ@1224|Proteobacteria,1RQFM@1236|Gammaproteobacteria,1XT7J@135623|Vibrionales 135623|Vibrionales L COG0419 ATPase involved in DNA repair sbcC GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006260,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901576 - ko:K03546 - - - - ko00000,ko03400 - - - AAA_23,AAA_29,SbcCD_C k141_27917_18 1115512.EH105704_01_03740 5.44e-162 461.0 COG1879@1|root,COG1879@2|Bacteria,1MUAT@1224|Proteobacteria,1RP2R@1236|Gammaproteobacteria,3XPB1@561|Escherichia 1236|Gammaproteobacteria G Periplasmic binding protein domain lsrB_2 - - ko:K02058 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - Peripla_BP_4 k141_27917_19 911008.GLAD_00668 2.37e-197 565.0 COG1129@1|root,COG1129@2|Bacteria,1MU22@1224|Proteobacteria,1RSEP@1236|Gammaproteobacteria 1236|Gammaproteobacteria G ABC transporter - - 3.6.3.17 ko:K02056 - M00221 - - ko00000,ko00002,ko01000,ko02000 3.A.1.2 - - ABC_tran k141_27917_20 1115512.EH105704_01_03760 1.3e-153 441.0 COG1172@1|root,COG1172@2|Bacteria,1Q5HX@1224|Proteobacteria,1RRTE@1236|Gammaproteobacteria,3XPHM@561|Escherichia 1236|Gammaproteobacteria U Branched-chain amino acid transport system / permease component - - - ko:K02057 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - BPD_transp_2 k141_27917_21 1005999.GLGR_1956 1.34e-119 354.0 COG1172@1|root,COG1172@2|Bacteria,1MV1D@1224|Proteobacteria,1RRD6@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Belongs to the binding-protein-dependent transport system permease family lsrD_1 - - ko:K02057,ko:K10440 ko02010,map02010 M00212,M00221 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - BPD_transp_2 k141_19883_2 1116375.VEJY3_10815 1.11e-187 526.0 COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,1RR1N@1236|Gammaproteobacteria,1XSVW@135623|Vibrionales 135623|Vibrionales S ABC transporter substrate-binding protein - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind k141_19883_3 1116375.VEJY3_10810 3.82e-190 531.0 COG4120@1|root,COG4120@2|Bacteria,1MXGE@1224|Proteobacteria,1RY3E@1236|Gammaproteobacteria,1XUY5@135623|Vibrionales 135623|Vibrionales S Belongs to the binding-protein-dependent transport system permease family - - - ko:K05832 - M00247 - - ko00000,ko00002,ko02000 - - - BPD_transp_2 k141_19883_4 223926.28807071 1.13e-179 501.0 COG1101@1|root,COG1101@2|Bacteria,1MVDM@1224|Proteobacteria,1RSNT@1236|Gammaproteobacteria,1XUIF@135623|Vibrionales 135623|Vibrionales S abc transporter atp-binding protein - - - ko:K05833 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_tran k141_7894_1 218284.CCDN010000006_gene3609 6.88e-115 350.0 COG0557@1|root,COG0557@2|Bacteria,1TQ1G@1239|Firmicutes,4HBBH@91061|Bacilli,1ZBDP@1386|Bacillus 91061|Bacilli K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs rnr - - ko:K12573 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03016,ko03019 - - - OB_RNB,RNB,S1 k141_18839_1 218284.CCDN010000007_gene4010 6.28e-128 369.0 2DSIK@1|root,33GA6@2|Bacteria,1VN6K@1239|Firmicutes,4HSJR@91061|Bacilli,1ZHV5@1386|Bacillus 91061|Bacilli S TATA-box binding ywmB - - - - - - - - - - - DUF1779 k141_17369_1 744872.Spica_1193 1.32e-33 131.0 COG2204@1|root,COG2204@2|Bacteria,2J6EQ@203691|Spirochaetes 203691|Spirochaetes T response regulator - - - ko:K07714 ko02020,map02020 M00500 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat k141_27918_1 218284.CCDN010000001_gene508 7.58e-114 355.0 COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,4H9T3@91061|Bacilli,1ZCIC@1386|Bacillus 91061|Bacilli L DNA polymerase dnaE - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon k141_23589_1 218284.CCDN010000002_gene2251 7.17e-53 180.0 COG0069@1|root,COG0069@2|Bacteria,1TSHA@1239|Firmicutes,4HA97@91061|Bacilli,1ZCQH@1386|Bacillus 91061|Bacilli E Belongs to the glutamate synthase family yerD GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.7.1 ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 - R00021,R10086 RC00006,RC00010 ko00000,ko00001,ko01000 - - - Glu_synthase k141_12874_6 1116375.VEJY3_13725 1.05e-306 838.0 COG0312@1|root,COG0312@2|Bacteria,1MUVW@1224|Proteobacteria,1RPJF@1236|Gammaproteobacteria,1XSU9@135623|Vibrionales 135623|Vibrionales S Zn-dependent proteases and their inactivated homologs pmbA - - ko:K03592 - - - - ko00000,ko01002 - - - PmbA_TldD k141_12874_7 1116375.VEJY3_13720 9.85e-275 757.0 COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,1RNE4@1236|Gammaproteobacteria,1XU5X@135623|Vibrionales 135623|Vibrionales P Acts as a magnesium transporter mgtE - - ko:K06213 - - - - ko00000,ko02000 1.A.26.1 - - CBS,MgtE,MgtE_N k141_36315_1 218284.CCDN010000010_gene4329 1.23e-132 382.0 COG0489@1|root,COG0489@2|Bacteria,1TQ34@1239|Firmicutes,4HAW4@91061|Bacilli,1ZC2E@1386|Bacillus 91061|Bacilli D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP mrp GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K03593 - - - - ko00000,ko03029,ko03036 - - - FeS_assembly_P,ParA k141_27945_1 218284.CCDN010000007_gene3832 2.28e-100 292.0 COG1576@1|root,COG1576@2|Bacteria,1V3JM@1239|Firmicutes,4HFP8@91061|Bacilli,1ZFK3@1386|Bacillus 91061|Bacilli J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA rlmH - 2.1.1.177 ko:K00783 - - - - ko00000,ko01000,ko03009 - - - SPOUT_MTase k141_19898_1 218284.CCDN010000001_gene1009 1.11e-50 165.0 COG0406@1|root,COG0406@2|Bacteria,1V7F8@1239|Firmicutes,4HIR1@91061|Bacilli,1ZHAP@1386|Bacillus 91061|Bacilli G Phosphoglycerate mutase gpmA1 - 5.4.2.11 ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - His_Phos_1 k141_6862_1 1279017.AQYJ01000028_gene2101 5.9e-61 209.0 COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,1RN05@1236|Gammaproteobacteria,46ABX@72275|Alteromonadaceae 1236|Gammaproteobacteria S Insulinase (Peptidase family M16) pqqL - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C k141_6862_2 1236541.BALL01000018_gene2469 5.86e-104 318.0 COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria,2Q8YZ@267890|Shewanellaceae 1236|Gammaproteobacteria O PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - - - - - - - - - - PA,PKD,Peptidase_S8 k141_14190_1 218284.CCDN010000002_gene2724 9.49e-147 430.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1TQ85@1239|Firmicutes,4HAC0@91061|Bacilli,1ZR0Z@1386|Bacillus 91061|Bacilli EU Dienelactone hydrolase family - - - - - - - - - - - - PD40,Peptidase_S9,Peptidase_S9_N k141_20925_1 1131730.BAVI_22093 3.15e-59 197.0 COG0840@1|root,COG0840@2|Bacteria,1TRTV@1239|Firmicutes,4H9M1@91061|Bacilli,1ZBCT@1386|Bacillus 91061|Bacilli NT chemotaxis protein hemAT GO:0003674,GO:0005488,GO:0006935,GO:0007154,GO:0007165,GO:0008150,GO:0009453,GO:0009454,GO:0009605,GO:0009987,GO:0020037,GO:0023052,GO:0040011,GO:0042221,GO:0042330,GO:0046906,GO:0048037,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0097159,GO:1901363 - ko:K06595 - - - - ko00000,ko02035 - - - MCPsignal,Protoglobin k141_32817_1 1453501.JELR01000001_gene2146 1.31e-190 540.0 COG1680@1|root,COG1680@2|Bacteria,1QD0J@1224|Proteobacteria,1RZUZ@1236|Gammaproteobacteria,46CRC@72275|Alteromonadaceae 1236|Gammaproteobacteria V Beta-lactamase estC - - - - - - - - - - - Beta-lactamase k141_32817_2 1453501.JELR01000001_gene2147 5.37e-22 87.8 COG2900@1|root,COG2900@2|Bacteria 2|Bacteria S Belongs to the SlyX family slyX - - ko:K03745 - - - - ko00000 - - - SlyX k141_18883_2 1453501.JELR01000002_gene567 2.66e-76 231.0 COG1432@1|root,COG1432@2|Bacteria,1MUAE@1224|Proteobacteria,1S47Z@1236|Gammaproteobacteria,466XA@72275|Alteromonadaceae 1236|Gammaproteobacteria S NYN domain - - - - - - - - - - - - NYN k141_931_1 42565.FP66_13510 6.05e-96 280.0 COG1734@1|root,COG1734@2|Bacteria,1RD08@1224|Proteobacteria,1S47H@1236|Gammaproteobacteria,1XJPG@135619|Oceanospirillales 135619|Oceanospirillales T Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression dksA - - ko:K06204 ko02026,map02026 - - - ko00000,ko00001,ko03000,ko03009,ko03021 - - - zf-dskA_traR k141_35384_1 1042377.AFPJ01000028_gene2218 0.0 880.0 COG0281@1|root,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,1RQ11@1236|Gammaproteobacteria,465JN@72275|Alteromonadaceae 1236|Gammaproteobacteria C malic enzyme maeA GO:0003674,GO:0003824,GO:0004470,GO:0004471,GO:0004473,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006094,GO:0006108,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016051,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0019318,GO:0019319,GO:0019752,GO:0032787,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0055114,GO:0071704,GO:1901576 1.1.1.38,1.1.1.40 ko:K00027,ko:K00029 ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020 M00169,M00172 R00214,R00216 RC00105 ko00000,ko00001,ko00002,ko01000 - - iSbBS512_1146.SbBS512_E1742 Malic_M,malic k141_35384_2 1042377.AFPJ01000020_gene2065 2.67e-167 478.0 COG0053@1|root,COG0053@2|Bacteria,1MVH8@1224|Proteobacteria,1RQ3E@1236|Gammaproteobacteria,46BQ5@72275|Alteromonadaceae 1236|Gammaproteobacteria U Cation efflux family catA - - - - - - - - - - - Cation_efflux,ZT_dimer k141_35384_3 1042377.AFPJ01000020_gene2064 0.0 873.0 COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,1RN2V@1236|Gammaproteobacteria 1236|Gammaproteobacteria P COG3119 Arylsulfatase A and related enzymes - - 3.1.6.1 ko:K01130 ko00140,ko00600,map00140,map00600 - R03980,R04856 RC00128,RC00231 ko00000,ko00001,ko01000 - - - Sulfatase,Sulfatase_C k141_35384_4 1042377.AFPJ01000020_gene2062 3.58e-161 470.0 COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,1RN2V@1236|Gammaproteobacteria 1236|Gammaproteobacteria P COG3119 Arylsulfatase A and related enzymes - - 3.1.6.1 ko:K01130 ko00140,ko00600,map00140,map00600 - R03980,R04856 RC00128,RC00231 ko00000,ko00001,ko01000 - - - Sulfatase,Sulfatase_C k141_7926_1 1279017.AQYJ01000029_gene3320 1.54e-115 338.0 COG1076@1|root,COG1076@2|Bacteria,1N270@1224|Proteobacteria,1RP0P@1236|Gammaproteobacteria,4673B@72275|Alteromonadaceae 1236|Gammaproteobacteria O Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host djlA - - ko:K05801 - - - - ko00000,ko03110 - - - DnaJ,TerB k141_7926_2 1453501.JELR01000001_gene2737 2.15e-55 174.0 COG0271@1|root,COG0271@2|Bacteria,1MZG5@1224|Proteobacteria,1S91G@1236|Gammaproteobacteria,46865@72275|Alteromonadaceae 1236|Gammaproteobacteria T Belongs to the BolA IbaG family bolA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - ko:K05527 - - - - ko00000,ko03000 - - - BolA k141_27155_1 377629.TERTU_2540 9.23e-56 182.0 COG1714@1|root,COG1714@2|Bacteria,1RIE9@1224|Proteobacteria,1S566@1236|Gammaproteobacteria,2PPWH@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria S RDD family - - - - - - - - - - - - RDD k141_27155_2 305900.GV64_07355 1.99e-52 177.0 COG5523@1|root,COG5523@2|Bacteria,1RGXF@1224|Proteobacteria,1S7NN@1236|Gammaproteobacteria,1XP9U@135619|Oceanospirillales 135619|Oceanospirillales S integral membrane protein - - - - - - - - - - - - - k141_27155_3 1279017.AQYJ01000028_gene2066 7.45e-39 139.0 2DMKM@1|root,32S7K@2|Bacteria,1NH6E@1224|Proteobacteria 1224|Proteobacteria S Protein of unknown function (DUF2939) - - - - - - - - - - - - DUF2939 k141_27155_4 1279017.AQYJ01000028_gene2067 1.4e-71 216.0 COG3651@1|root,COG3651@2|Bacteria,1RH68@1224|Proteobacteria,1S7KX@1236|Gammaproteobacteria,46CDB@72275|Alteromonadaceae 1236|Gammaproteobacteria S Uncharacterized protein conserved in bacteria (DUF2237) - - - ko:K09966 - - - - ko00000 - - - DUF2237 k141_27155_5 1042377.AFPJ01000015_gene1615 1.17e-107 319.0 COG0388@1|root,COG0388@2|Bacteria,1MUUB@1224|Proteobacteria,1RNVZ@1236|Gammaproteobacteria,466U1@72275|Alteromonadaceae 1236|Gammaproteobacteria S amidohydrolase ramA - 3.5.5.1 ko:K01501,ko:K11206 ko00380,ko00460,ko00627,ko00643,ko00910,ko01120,map00380,map00460,map00627,map00643,map00910,map01120 - R00540,R01887,R03093,R03542,R05591,R07855 RC00315,RC00325,RC00617,RC00959,RC02811 ko00000,ko00001,ko01000 - - - CN_hydrolase k141_24520_1 523791.Kkor_0931 1.04e-23 100.0 COG0726@1|root,COG0726@2|Bacteria,1RA45@1224|Proteobacteria,1S2JF@1236|Gammaproteobacteria 1236|Gammaproteobacteria G polysaccharide deacetylase - - - - - - - - - - - - Polysacc_deac_1 k141_24520_2 945550.VISI1226_10682 3.29e-212 596.0 COG0677@1|root,COG0677@2|Bacteria,1MUC6@1224|Proteobacteria,1RMX0@1236|Gammaproteobacteria,1XSY5@135623|Vibrionales 135623|Vibrionales M Belongs to the UDP-glucose GDP-mannose dehydrogenase family epsD - 1.1.1.336 ko:K02472 ko00520,ko05111,map00520,map05111 - R03317 RC00291 ko00000,ko00001,ko01000 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N k141_14031_1 218284.CCDN010000006_gene3542 2.78e-138 399.0 COG1979@1|root,COG1979@2|Bacteria,1TPS3@1239|Firmicutes,4HT1J@91061|Bacilli,1ZEGP@1386|Bacillus 91061|Bacilli C Iron-containing alcohol dehydrogenase - - - ko:K19955 - - - - ko00000,ko01000 - - - Fe-ADH k141_20844_1 913325.N799_02695 6.82e-42 148.0 COG1694@1|root,COG3956@2|Bacteria,1MVKM@1224|Proteobacteria,1RNVU@1236|Gammaproteobacteria,1X2Z9@135614|Xanthomonadales 135614|Xanthomonadales S Nucleoside triphosphate mazG - 3.6.1.9 ko:K04765 ko00230,ko00240,ko00760,ko00770,ko01100,map00230,map00240,map00760,map00770,map01100 - R00086,R00087,R00103,R00287,R00426,R00515,R00662,R00720,R03004,R03036,R11323 RC00002 ko00000,ko00001,ko01000 - - - MazG k141_3005_1 1279017.AQYJ01000029_gene3313 0.0 974.0 COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,1QTTG@1224|Proteobacteria,1RNG6@1236|Gammaproteobacteria,4659U@72275|Alteromonadaceae 1236|Gammaproteobacteria CI COG5016 Pyruvate oxaloacetate carboxyltransferase oadA - 4.1.1.3 ko:K01571 ko00620,ko01100,map00620,map01100 - R00217 RC00040 ko00000,ko00001,ko01000,ko02000 3.B.1.1.1 - - Biotin_lipoyl,HMGL-like,PYC_OADA k141_3005_2 1279017.AQYJ01000029_gene3312 9.17e-30 107.0 COG3630@1|root,COG3630@2|Bacteria,1NERX@1224|Proteobacteria,1SD6N@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Oxaloacetate decarboxylase, gamma chain - - - - - - - - - - - - OAD_gamma k141_3005_3 1279017.AQYJ01000029_gene3311 1.1e-182 514.0 COG0042@1|root,COG0042@2|Bacteria,1MUSM@1224|Proteobacteria,1RMMM@1236|Gammaproteobacteria,4649D@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs dusC GO:0000049,GO:0000166,GO:0002943,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010181,GO:0010467,GO:0016070,GO:0016491,GO:0016627,GO:0017150,GO:0032553,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0048037,GO:0050662,GO:0055114,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363 - ko:K05541 - - - - ko00000,ko01000,ko03016 - - - Dus k141_3005_4 1479237.JMLY01000001_gene2625 1.68e-32 125.0 COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,1RPAV@1236|Gammaproteobacteria,463XQ@72275|Alteromonadaceae 1236|Gammaproteobacteria L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA ligA GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003909,GO:0003911,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0034645,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050662,GO:0050896,GO:0051103,GO:0051287,GO:0051716,GO:0070403,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1901576 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - iEC55989_1330.EC55989_2701,iECABU_c1320.ECABU_c27320,iECIAI1_1343.ECIAI1_2469,iECO103_1326.ECO103_2930,iECO111_1330.ECO111_3141,iECO26_1355.ECO26_3464,iECSE_1348.ECSE_2702,iECW_1372.ECW_m2640,iEKO11_1354.EKO11_1317,iEcE24377_1341.EcE24377A_2698,iEcSMS35_1347.EcSMS35_2566,iWFL_1372.ECW_m2640,iYL1228.KPN_02758,ic_1306.c2945 BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5 k141_25835_3 243277.VC_1785 2.12e-26 97.8 COG3311@1|root,COG3311@2|Bacteria,1NGB9@1224|Proteobacteria,1SGDV@1236|Gammaproteobacteria,1XZ0B@135623|Vibrionales 135623|Vibrionales K Transcriptional regulator - - - ko:K07733 - - - - ko00000,ko03000 - - - Phage_AlpA k141_25835_4 1219065.VPR01S_25_00730 1.17e-76 232.0 COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,1S5A5@1236|Gammaproteobacteria,1XWPP@135623|Vibrionales 135623|Vibrionales E Belongs to the UPF0758 family - - - ko:K03630 - - - - ko00000 - - - RadC k141_25835_7 1454202.PPBDW_140026___1 6.22e-37 135.0 2CZQX@1|root,32T6W@2|Bacteria,1MZGE@1224|Proteobacteria,1S91C@1236|Gammaproteobacteria,1XX7E@135623|Vibrionales 135623|Vibrionales S Inovirus Gp2 - - - - - - - - - - - - Inovirus_Gp2 k141_25835_9 1219076.N646_4143 1.18e-136 391.0 COG1161@1|root,COG1161@2|Bacteria,1MV5H@1224|Proteobacteria,1RP79@1236|Gammaproteobacteria,1XSKP@135623|Vibrionales 135623|Vibrionales S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity rbgA - - ko:K14540 - - - - ko00000,ko03009 - - - MMR_HSR1 k141_6731_1 1408303.JNJJ01000011_gene1419 1.81e-58 192.0 COG0673@1|root,COG0673@2|Bacteria,1USVA@1239|Firmicutes,4HDVM@91061|Bacilli,1ZQBZ@1386|Bacillus 91061|Bacilli S Oxidoreductase family, NAD-binding Rossmann fold - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C k141_10377_1 218284.CCDN010000002_gene2093 3.32e-128 374.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,1ZB7V@1386|Bacillus 91061|Bacilli I Belongs to the thiolase family pcaF - 2.3.1.174,2.3.1.223 ko:K02615 ko00360,ko01120,map00360,map01120 - R00829,R09839 RC00004,RC00326,RC03003 ko00000,ko00001,ko01000 - - - Thiolase_C,Thiolase_N k141_5625_1 1123239.KB898623_gene1549 1.14e-13 72.4 COG1544@1|root,COG1544@2|Bacteria,1V1D5@1239|Firmicutes,4HFX9@91061|Bacilli 91061|Bacilli J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase hpf GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - ko:K05808 - - - - ko00000,ko03009 - - - Ribosom_S30AE_C,Ribosomal_S30AE k141_27156_1 1294265.JCM21738_1901 1.75e-115 332.0 COG0332@1|root,COG0332@2|Bacteria,1TPDE@1239|Firmicutes,4H9W9@91061|Bacilli,1ZAW8@1386|Bacillus 91061|Bacilli I Stage V sporulation protein AD spoVAD - - ko:K06406 - - - - ko00000 - - - SpoVAD k141_36232_2 1453501.JELR01000002_gene545 1.3e-99 290.0 COG1327@1|root,COG1327@2|Bacteria,1RE7V@1224|Proteobacteria,1S3P9@1236|Gammaproteobacteria,466Q5@72275|Alteromonadaceae 1236|Gammaproteobacteria K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes nrdR GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005524,GO:0006355,GO:0008144,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K07738 - - - - ko00000,ko03000 - - - ATP-cone k141_18723_3 207954.MED92_13361 6.61e-43 142.0 COG2329@1|root,COG2329@2|Bacteria,1N062@1224|Proteobacteria,1S9PR@1236|Gammaproteobacteria,1XKPX@135619|Oceanospirillales 135619|Oceanospirillales H enzyme involved in biosynthesis of extracellular polysaccharides - - - - - - - - - - - - ABM k141_18723_4 1117647.M5M_11050 8.76e-140 402.0 COG3221@1|root,COG3221@2|Bacteria,1MWFF@1224|Proteobacteria,1RSFI@1236|Gammaproteobacteria,1J5DW@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P COG3221 ABC-type phosphate phosphonate transport system, periplasmic component phnD - - ko:K02044 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - Phosphonate-bd k141_18723_5 460265.Mnod_3493 1.24e-50 171.0 COG3638@1|root,COG3638@2|Bacteria,1RF8E@1224|Proteobacteria,2U0DC@28211|Alphaproteobacteria,1JSCU@119045|Methylobacteriaceae 28211|Alphaproteobacteria P ATPases associated with a variety of cellular activities - - 3.6.3.28 ko:K02041 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.9 - - ABC_tran k141_18723_6 1411685.U062_00446 9.24e-76 247.0 COG3639@1|root,COG3639@2|Bacteria,1N3HU@1224|Proteobacteria,1RYH5@1236|Gammaproteobacteria,1J7WT@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P COG3639 ABC-type phosphate phosphonate transport system, permease component phnE - - ko:K02042 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - BPD_transp_1 k141_25836_1 1045004.OKIT_1404 9.39e-31 115.0 COG1434@1|root,COG1434@2|Bacteria,1V973@1239|Firmicutes,4HJHS@91061|Bacilli 91061|Bacilli S DUF218 domain - - - - - - - - - - - - DUF218 k141_25836_2 1460640.JCM19046_4397 1.59e-07 53.5 COG1051@1|root,COG1051@2|Bacteria,1V3T8@1239|Firmicutes,4HH2F@91061|Bacilli,1ZFSN@1386|Bacillus 91061|Bacilli F NIPSNAP - - - - - - - - - - - - NIPSNAP,NUDIX k141_7787_1 283699.D172_0295 2.91e-82 251.0 COG0681@1|root,COG0681@2|Bacteria,1R7Z4@1224|Proteobacteria,1RX6N@1236|Gammaproteobacteria,2Q0CM@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria U Belongs to the peptidase S26 family - - 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24,Peptidase_S26 k141_3006_1 1283284.AZUK01000001_gene1799 7.76e-53 184.0 COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,1RR5Z@1236|Gammaproteobacteria,1Y6FV@135624|Aeromonadales 135624|Aeromonadales J Amidase - - 3.5.1.54 ko:K01457 ko00220,ko00791,ko01100,ko01120,map00220,map00791,map01100,map01120 - R00005 RC02756 ko00000,ko00001,ko01000 - - - Amidase k141_11563_2 1279017.AQYJ01000027_gene1755 4.39e-206 583.0 COG0534@1|root,COG0534@2|Bacteria,1MV6B@1224|Proteobacteria,1RPGF@1236|Gammaproteobacteria,46598@72275|Alteromonadaceae 1236|Gammaproteobacteria V COG0534 Na -driven multidrug efflux pump dinF - - ko:K03327 - - - - ko00000,ko02000 2.A.66.1 - - MatE k141_29221_1 203122.Sde_2938 4.63e-282 786.0 COG0366@1|root,COG0366@2|Bacteria,1MVQA@1224|Proteobacteria,1RPA4@1236|Gammaproteobacteria,46654@72275|Alteromonadaceae 1236|Gammaproteobacteria G COG0366 Glycosidases - - 3.2.1.1 ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 - R02108,R02112,R11262 - ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,Alpha-amylase_C,CBM26,CBM_20 k141_37453_1 1128421.JAGA01000001_gene2190 6.18e-88 268.0 COG0346@1|root,COG0346@2|Bacteria,2NR6J@2323|unclassified Bacteria 2|Bacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - ko:K15975 - - - - ko00000 - - - Glyoxalase k141_4271_1 1117647.M5M_06505 1.39e-227 648.0 COG1629@1|root,COG4771@2|Bacteria,1MUNK@1224|Proteobacteria,1RN9S@1236|Gammaproteobacteria,1J59B@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_25837_2 218284.CCDN010000005_gene3455 2.7e-25 100.0 COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,4H9V0@91061|Bacilli,1ZBBP@1386|Bacillus 91061|Bacilli O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides ppiA GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 - - - ko00000,ko00001,ko01000,ko03110,ko04147 - - - Pro_isomerase k141_20845_1 1307436.PBF_21058 1.89e-111 329.0 COG4120@1|root,COG4120@2|Bacteria,1TPDJ@1239|Firmicutes,4HBMY@91061|Bacilli,1ZAWA@1386|Bacillus 91061|Bacilli S Belongs to the binding-protein-dependent transport system permease family - - - ko:K05832 - M00247 - - ko00000,ko00002,ko02000 - - - BPD_transp_2 k141_27158_1 218284.CCDN010000007_gene3829 3.74e-66 207.0 COG1235@1|root,COG1235@2|Bacteria,1TQ8E@1239|Firmicutes,4HAKD@91061|Bacilli,1ZASY@1386|Bacillus 91061|Bacilli S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I vicX - 3.1.26.11 ko:K00784 ko03013,map03013 - - - ko00000,ko00001,ko01000,ko03016 - - - Lactamase_B,Lactamase_B_2 k141_12804_2 1279017.AQYJ01000024_gene1172 0.0 1533.0 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,1RMPV@1236|Gammaproteobacteria,465IY@72275|Alteromonadaceae 1236|Gammaproteobacteria F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdA - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN k141_6733_2 497965.Cyan7822_4618 1.24e-12 70.1 29WFE@1|root,30I19@2|Bacteria,1GQ76@1117|Cyanobacteria,3KIWC@43988|Cyanothece 1117|Cyanobacteria - - - - - - - - - - - - - - - k141_5627_1 1232683.ADIMK_2589 6.89e-36 138.0 COG3119@1|root,COG3119@2|Bacteria,1MV92@1224|Proteobacteria,1RPDE@1236|Gammaproteobacteria,464V5@72275|Alteromonadaceae 1236|Gammaproteobacteria P Sulfatase atsA - 3.1.6.1 ko:K01130 ko00140,ko00600,map00140,map00600 - R03980,R04856 RC00128,RC00231 ko00000,ko00001,ko01000 - - - Sulfatase k141_25838_1 218284.CCDN010000007_gene3847 2.37e-78 248.0 COG5444@1|root,COG5444@2|Bacteria,1VCIS@1239|Firmicutes,4HM2E@91061|Bacilli,1ZDH0@1386|Bacillus 91061|Bacilli S nuclease activity - - - - - - - - - - - - LXG k141_11564_1 981383.AEWH01000036_gene921 1.12e-102 301.0 COG0177@1|root,COG0177@2|Bacteria,1TRAK@1239|Firmicutes,4HATD@91061|Bacilli 91061|Bacilli L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate nth - 4.2.99.18 ko:K10773 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD k141_32697_1 1267535.KB906767_gene2573 5.61e-06 52.0 COG0475@1|root,COG0475@2|Bacteria,3Y5D3@57723|Acidobacteria,2JJMV@204432|Acidobacteriia 204432|Acidobacteriia P Sodium/hydrogen exchanger family - - - - - - - - - - - - Na_H_Exchanger k141_5628_1 324057.Pjdr2_1571 1.88e-47 171.0 29WXN@1|root,30IJR@2|Bacteria,1UJ5A@1239|Firmicutes,4IT24@91061|Bacilli,270DI@186822|Paenibacillaceae 91061|Bacilli - - - - - - - - - - - - - - - k141_3007_1 218284.CCDN010000001_gene675 1.52e-70 214.0 COG1725@1|root,COG1725@2|Bacteria,1VA2B@1239|Firmicutes,4HPK4@91061|Bacilli,1ZHSQ@1386|Bacillus 91061|Bacilli K Transcriptional regulator yhcF - - ko:K07979 - - - - ko00000,ko03000 - - - GntR k141_3007_2 218284.CCDN010000001_gene674 7.91e-41 141.0 2CHZZ@1|root,32S6Y@2|Bacteria,1VA01@1239|Firmicutes,4IJSI@91061|Bacilli,1ZJVW@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_34051_2 1453501.JELR01000001_gene2106 4.05e-18 84.3 COG1228@1|root,COG1228@2|Bacteria,1MXQX@1224|Proteobacteria,1RQGS@1236|Gammaproteobacteria,465N1@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Amidohydrolase family - - - - - - - - - - - - Amidohydro_1,Amidohydro_3 k141_29232_1 218284.CCDN010000002_gene2915 1.97e-114 344.0 COG0661@1|root,COG0661@2|Bacteria,1TPIV@1239|Firmicutes,4HBW3@91061|Bacilli,1ZBPH@1386|Bacillus 91061|Bacilli S ABC1 family ubiB - - - - - - - - - - - ABC1,APH,RIO1 k141_7813_1 218284.CCDN010000001_gene1930 1.02e-75 236.0 COG1317@1|root,COG1317@2|Bacteria,1V1H3@1239|Firmicutes,4IS1Y@91061|Bacilli,1ZS0H@1386|Bacillus 91061|Bacilli NU Flagellar assembly protein FliH fliH - - ko:K02411 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - FliH k141_5640_2 1163398.AJJP01000124_gene4698 3.89e-71 226.0 28HKZ@1|root,2Z7VP@2|Bacteria,1R4QW@1224|Proteobacteria,1RZQX@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF3050) - - - - - - - - - - - - DUF3050 k141_5640_3 388399.SSE37_10799 4.76e-76 235.0 COG4221@1|root,COG4221@2|Bacteria,1MUF8@1224|Proteobacteria,2TR5S@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short k141_14064_1 42565.FP66_13005 2.02e-135 397.0 COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,1RMD2@1236|Gammaproteobacteria,1XHHA@135619|Oceanospirillales 135619|Oceanospirillales E Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate betA - 1.1.99.1 ko:K00108 ko00260,ko01100,map00260,map01100 M00555 R01025 RC00087 ko00000,ko00001,ko00002,ko01000 - - - GMC_oxred_C,GMC_oxred_N k141_24553_1 1042377.AFPJ01000034_gene2356 7.1e-26 97.8 COG0792@1|root,COG0792@2|Bacteria,1N6VN@1224|Proteobacteria,1SC8A@1236|Gammaproteobacteria,468BF@72275|Alteromonadaceae 1236|Gammaproteobacteria L Belongs to the UPF0102 family yraN - - ko:K07460 - - - - ko00000 - - - UPF0102 k141_24553_2 1453501.JELR01000001_gene3059 8.86e-81 243.0 COG0279@1|root,COG0279@2|Bacteria,1NJ8X@1224|Proteobacteria,1RS1Y@1236|Gammaproteobacteria,466WU@72275|Alteromonadaceae 1236|Gammaproteobacteria G Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate gmhA - 5.3.1.28 ko:K03271,ko:K12961 ko00540,ko01100,map00540,map01100 M00064 R05645,R09768,R09769 RC00434 ko00000,ko00001,ko00002,ko01000,ko01005,ko03036 - - - SIS_2 k141_12817_1 333138.LQ50_24670 3.01e-24 95.1 2C4IU@1|root,32Z6Z@2|Bacteria,1VHVS@1239|Firmicutes,4HNKY@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - k141_17331_2 118168.MC7420_358 1.15e-69 221.0 COG1216@1|root,COG1216@2|Bacteria,1G2MT@1117|Cyanobacteria,1H8YG@1150|Oscillatoriales 1117|Cyanobacteria M Glycosyltransferase like family 2 - - - - - - - - - - - - Glyco_hydro_2_C,Glycos_transf_2 k141_22133_1 218284.CCDN010000007_gene4017 3.06e-162 467.0 COG4147@1|root,COG4147@2|Bacteria,1UHT5@1239|Firmicutes,4HCF6@91061|Bacilli,1ZCX7@1386|Bacillus 91061|Bacilli S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family ywcA - - ko:K14393 - - - - ko00000,ko02000 2.A.21.7 - - SSF k141_3026_1 1279038.KB907344_gene3553 1.18e-57 192.0 COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2TQKK@28211|Alphaproteobacteria,2JPC8@204441|Rhodospirillales 204441|Rhodospirillales EP Binding-protein-dependent transport system inner membrane component - - - ko:K02033 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 k141_3026_2 1121396.KB893127_gene3795 4.01e-133 396.0 COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,42N16@68525|delta/epsilon subdivisions,2WN4F@28221|Deltaproteobacteria,2MPTD@213118|Desulfobacterales 28221|Deltaproteobacteria E Bacterial extracellular solute-binding proteins, family 5 Middle - - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 k141_29233_1 42565.FP66_08240 1.89e-19 85.9 COG4531@1|root,COG4531@2|Bacteria,1QTTI@1224|Proteobacteria,1RMRJ@1236|Gammaproteobacteria,1XJ7U@135619|Oceanospirillales 135619|Oceanospirillales P ABC-type Zn2 transport system, periplasmic component surface adhesin - - - ko:K09815 ko02010,map02010 M00242 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15.3,3.A.1.15.5 - - ZnuA k141_29233_2 42565.FP66_08235 3.08e-70 217.0 COG1121@1|root,COG1121@2|Bacteria,1MUDW@1224|Proteobacteria,1RPJT@1236|Gammaproteobacteria,1XHPH@135619|Oceanospirillales 135619|Oceanospirillales P Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system znuC - - ko:K09817 ko02010,map02010 M00242 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.15.3,3.A.1.15.5 - - ABC_tran k141_36246_1 218284.CCDN010000007_gene3971 7.41e-209 583.0 COG0766@1|root,COG0766@2|Bacteria,1TPAU@1239|Firmicutes,4H9KI@91061|Bacilli,1ZASB@1386|Bacillus 91061|Bacilli M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine murA GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008760,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042221,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0070589,GO:0070887,GO:0071236,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R00660 RC00350 ko00000,ko00001,ko01000,ko01011 - - iYO844.BSU37100 EPSP_synthase k141_20860_1 649349.Lbys_2887 3.09e-44 149.0 COG1225@1|root,COG1225@2|Bacteria,4NNHI@976|Bacteroidetes,47PTD@768503|Cytophagia 976|Bacteroidetes O PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - 1.11.1.15 ko:K03564 - - - - ko00000,ko01000 - - - AhpC-TSA k141_20860_2 1479238.JQMZ01000001_gene2084 1.78e-27 116.0 COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2TSRP@28211|Alphaproteobacteria,43X75@69657|Hyphomonadaceae 28211|Alphaproteobacteria T signal transduction histidine kinase divJ GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 ko:K07716,ko:K11357 ko02020,ko04112,map02020,map04112 M00511 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS,PAS_3,PAS_4 k141_11587_2 1453501.JELR01000002_gene774 3.03e-125 374.0 COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,1RU5N@1236|Gammaproteobacteria,463XR@72275|Alteromonadaceae 1236|Gammaproteobacteria S Sulfotransferase domain - - - - - - - - - - - - Sulfotransfer_3,TPR_16,TPR_17,TPR_2,TPR_8 k141_7814_1 218284.CCDN010000001_gene79 4.83e-131 382.0 COG0849@1|root,COG0849@2|Bacteria,1TP1Z@1239|Firmicutes,4H9NF@91061|Bacilli,1ZBH1@1386|Bacillus 91061|Bacilli D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring ftsA GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032153,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0098552,GO:0098562 - ko:K03590 ko04112,map04112 - - - ko00000,ko00001,ko03036,ko04812 - - - DUF3484,FtsA,SHS2_FTSA k141_25857_1 1042377.AFPJ01000053_gene1516 2.09e-149 431.0 COG2067@1|root,COG2067@2|Bacteria,1MV7W@1224|Proteobacteria,1RPTU@1236|Gammaproteobacteria,469RP@72275|Alteromonadaceae 1236|Gammaproteobacteria I Outer membrane protein transport protein (OMPP1/FadL/TodX) - - - ko:K06076 - - - - ko00000,ko02000 1.B.9 - - Toluene_X k141_865_1 1121090.KB894697_gene1990 2.68e-100 306.0 COG1292@1|root,COG1292@2|Bacteria,1TRS6@1239|Firmicutes,4HA7U@91061|Bacilli,1ZBRN@1386|Bacillus 91061|Bacilli M Belongs to the BCCT transporter (TC 2.A.15) family opuD GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0016020,GO:0031460,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0072337 - ko:K05020 - - - - ko00000,ko02000 2.A.15.1.1,2.A.15.1.11 - iYO844.BSU30070 BCCT k141_14943_1 935837.JAEK01000004_gene4658 2.75e-48 159.0 COG1051@1|root,COG1051@2|Bacteria,1V4TX@1239|Firmicutes,4HH70@91061|Bacilli,1ZGXJ@1386|Bacillus 91061|Bacilli F Belongs to the Nudix hydrolase family - - - - - - - - - - - - NUDIX k141_31431_2 1042377.AFPJ01000012_gene1375 4.73e-148 422.0 COG2771@1|root,COG2771@2|Bacteria,1QW0I@1224|Proteobacteria,1T5AY@1236|Gammaproteobacteria 1236|Gammaproteobacteria K helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE k141_9175_1 1007103.AFHW01000153_gene933 3.9e-25 102.0 COG0666@1|root,COG0666@2|Bacteria,1V657@1239|Firmicutes,4HIDE@91061|Bacilli,26WY6@186822|Paenibacillaceae 91061|Bacilli S Ankyrin repeat - - - - - - - - - - - - Ank_2,Ank_4,Ank_5 k141_9175_2 218284.CCDN010000001_gene1824 1.55e-11 63.5 COG0550@1|root,COG0551@1|root,COG0550@2|Bacteria,COG0551@2|Bacteria,1TPJD@1239|Firmicutes,4HAZV@91061|Bacilli,1ZBEG@1386|Bacillus 91061|Bacilli L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topB - 5.99.1.2 ko:K03169 - - - - ko00000,ko01000,ko03032 - - - Topoisom_bac,Toprim k141_18757_2 218284.CCDN010000001_gene1203 4.5e-35 122.0 298S5@1|root,2ZVWF@2|Bacteria,1V8I3@1239|Firmicutes,4HHTT@91061|Bacilli,1ZH6F@1386|Bacillus 91061|Bacilli S Protein of unknown function with PCYCGC motif - - - - - - - - - - - - PCYCGC k141_37467_1 1116375.VEJY3_19776 1.87e-291 801.0 COG3288@1|root,COG3288@2|Bacteria,1MVXU@1224|Proteobacteria,1RN23@1236|Gammaproteobacteria,1XU8J@135623|Vibrionales 135623|Vibrionales C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane pntA - 1.6.1.2 ko:K00324 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - AlaDh_PNT_C,AlaDh_PNT_N,PNTB_4TM k141_37467_2 1116375.VEJY3_19781 4.54e-316 862.0 COG1282@1|root,COG1282@2|Bacteria,1MUP4@1224|Proteobacteria,1RMR4@1236|Gammaproteobacteria,1XT5B@135623|Vibrionales 135623|Vibrionales C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane pntB - 1.6.1.2 ko:K00325 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - PNTB k141_37467_3 674977.VMC_32440 1.98e-155 449.0 COG0642@1|root,COG0642@2|Bacteria,1R9IX@1224|Proteobacteria,1SMI3@1236|Gammaproteobacteria,1XTIK@135623|Vibrionales 135623|Vibrionales T COG0642 Signal transduction histidine kinase - - - - - - - - - - - - DUF3404,HATPase_c,HisKA k141_19794_1 1294265.JCM21738_3667 1.62e-18 87.0 COG0115@1|root,COG0115@2|Bacteria,1TSIP@1239|Firmicutes,4HC7K@91061|Bacilli,1ZCRC@1386|Bacillus 91061|Bacilli EH 4-amino-4-deoxychorismate lyase pabC - 4.1.3.38 ko:K02619 ko00790,map00790 - R05553 RC01843,RC02148 ko00000,ko00001,ko01000 - - - Aminotran_4 k141_4292_2 1123072.AUDH01000011_gene3606 1.21e-42 157.0 COG1574@1|root,COG1574@2|Bacteria,1R53N@1224|Proteobacteria,2VF84@28211|Alphaproteobacteria,2JYNZ@204441|Rhodospirillales 204441|Rhodospirillales S Amidohydrolase family - - - - - - - - - - - - Amidohydro_3 k141_35564_2 1123256.KB907925_gene1459 4.02e-09 61.2 COG1680@1|root,COG1680@2|Bacteria,1N4ZM@1224|Proteobacteria,1SB6F@1236|Gammaproteobacteria,1X7T3@135614|Xanthomonadales 135614|Xanthomonadales V Beta-lactamase - - - - - - - - - - - - Beta-lactamase k141_22513_1 218284.CCDN010000001_gene594 1.18e-144 429.0 COG0466@1|root,COG0466@2|Bacteria,1TNYG@1239|Firmicutes,4HAZK@91061|Bacilli,1ZAXX@1386|Bacillus 91061|Bacilli O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner lon GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.4.21.53 ko:K01338 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - AAA,LON_substr_bdg,Lon_C k141_26113_1 218284.CCDN010000008_gene4201 8.35e-141 399.0 COG0220@1|root,COG0220@2|Bacteria,1TQCA@1239|Firmicutes,4HC08@91061|Bacilli,1ZAP2@1386|Bacillus 91061|Bacilli J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA trmB GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 ko:K03439 - - - - ko00000,ko01000,ko03016 - - - Methyltransf_4 k141_35565_1 1408254.T458_17105 1.26e-05 45.4 COG0346@1|root,COG0346@2|Bacteria 2|Bacteria E lactoylglutathione lyase activity - - - - - - - - - - - - Glyoxalase k141_35565_2 218284.CCDN010000001_gene240 5.72e-51 166.0 COG1051@1|root,COG1051@2|Bacteria,1V6Q0@1239|Firmicutes,4HIKK@91061|Bacilli,1ZH3B@1386|Bacillus 91061|Bacilli F Belongs to the Nudix hydrolase family - - - - - - - - - - - - NUDIX k141_20096_1 218284.CCDN010000007_gene3792 1.98e-178 505.0 COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,4H9MW@91061|Bacilli,1ZBKI@1386|Bacillus 91061|Bacilli L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids dnaA GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - ko:K02313 ko02020,ko04112,map02020,map04112 - - - ko00000,ko00001,ko03032,ko03036 - - - Bac_DnaA,Bac_DnaA_C,DnaA_N k141_13000_3 1279017.AQYJ01000027_gene1816 1.18e-93 276.0 COG0712@1|root,COG0712@2|Bacteria,1MVRH@1224|Proteobacteria,1S8X2@1236|Gammaproteobacteria,467HG@72275|Alteromonadaceae 1236|Gammaproteobacteria C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpH GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - iSF_1195.SF3815,iSFxv_1172.SFxv_4157,iS_1188.S3953 OSCP k141_28107_1 1116375.VEJY3_23686 1.72e-57 181.0 COG3339@1|root,COG3339@2|Bacteria,1MZR5@1224|Proteobacteria,1THZT@1236|Gammaproteobacteria,1XY14@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF1232) - - - - - - - - - - - - DUF1232 k141_28107_2 1280001.BAOA01000157_gene4763 1.13e-72 222.0 COG0744@1|root,COG0744@2|Bacteria,1RDAQ@1224|Proteobacteria,1RMGB@1236|Gammaproteobacteria,1XWFV@135623|Vibrionales 135623|Vibrionales M Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors mtgA - 2.4.1.129 ko:K03814 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly k141_1126_1 1123508.JH636452_gene7007 1.31e-112 350.0 COG1506@1|root,COG1506@2|Bacteria,2IYRT@203682|Planctomycetes 203682|Planctomycetes E Dipeptidyl peptidase IV (DPP IV) - - 3.4.14.5 ko:K01278 ko04974,map04974 - - - ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 - - - DPPIV_N,Peptidase_S9 k141_32995_2 1279017.AQYJ01000029_gene3590 6.98e-56 180.0 2CH72@1|root,31GTD@2|Bacteria,1QEGI@1224|Proteobacteria,1TB5S@1236|Gammaproteobacteria,4697T@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF2878) - - - - - - - - - - - - DUF2878 k141_32995_3 1042377.AFPJ01000009_gene280 1.22e-212 599.0 COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,1RNID@1236|Gammaproteobacteria,464X8@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG2230 Cyclopropane fatty acid synthase and related methyltransferases cfa - 2.1.1.79 ko:K00574 - - - - ko00000,ko01000 - - iJN746.PP_2734 CMAS k141_32995_4 1279017.AQYJ01000029_gene3588 2.61e-139 399.0 COG3496@1|root,COG3496@2|Bacteria,1RC56@1224|Proteobacteria,1RRT8@1236|Gammaproteobacteria,465C9@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF1365) - - - ko:K09701 - - - - ko00000 - - - DUF1365 k141_32995_5 1279017.AQYJ01000029_gene3587 1.12e-230 643.0 COG2907@1|root,COG2907@2|Bacteria,1MV4Z@1224|Proteobacteria,1RP4P@1236|Gammaproteobacteria,464DX@72275|Alteromonadaceae 1236|Gammaproteobacteria S NAD FAD-binding protein - - - ko:K06954 - - - - ko00000 - - - Amino_oxidase,NAD_binding_8 k141_32995_6 1042377.AFPJ01000009_gene283 5.34e-116 340.0 COG0300@1|root,COG0300@2|Bacteria,1R735@1224|Proteobacteria,1RSHH@1236|Gammaproteobacteria,467CS@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) sdh - - - - - - - - - - - adh_short k141_32995_7 1279017.AQYJ01000029_gene3585 1.75e-55 177.0 COG3631@1|root,COG3631@2|Bacteria,1MZS5@1224|Proteobacteria,1S8VN@1236|Gammaproteobacteria,468AD@72275|Alteromonadaceae 1236|Gammaproteobacteria S SnoaL-like domain - - - - - - - - - - - - SnoaL_2 k141_32995_8 1279017.AQYJ01000029_gene3584 2.17e-92 275.0 COG1595@1|root,COG1595@2|Bacteria,1RHRR@1224|Proteobacteria,1S2UD@1236|Gammaproteobacteria,46820@72275|Alteromonadaceae 1236|Gammaproteobacteria K Belongs to the sigma-70 factor family. ECF subfamily sigY - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4,Sigma70_r4_2 k141_32995_9 1453501.JELR01000001_gene2124 1.62e-85 260.0 COG3806@1|root,COG3806@2|Bacteria,1RI6T@1224|Proteobacteria,1S2IS@1236|Gammaproteobacteria,46DNT@72275|Alteromonadaceae 1236|Gammaproteobacteria T AntiSigma factor chrR - - ko:K07167 - - - - ko00000 - - - Cupin_7 k141_32995_10 1279017.AQYJ01000029_gene3582 0.0 1274.0 COG1014@1|root,COG4231@1|root,COG1014@2|Bacteria,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,1RSEQ@1236|Gammaproteobacteria,465RF@72275|Alteromonadaceae 1236|Gammaproteobacteria C Pyruvate ferredoxin/flavodoxin oxidoreductase - - 1.2.7.8 ko:K04090 - - - - br01601,ko00000,ko01000 - - - POR,TPP_enzyme_C k141_29489_1 1395571.TMS3_0109405 1.12e-125 365.0 COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,1RS05@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Belongs to the pirin family - - - ko:K06911 - - - - ko00000 - - - Pirin,Pirin_C k141_21042_1 218284.CCDN010000007_gene3979 9.34e-234 645.0 COG0216@1|root,COG0216@2|Bacteria,1TQ7V@1239|Firmicutes,4H9MB@91061|Bacilli,1ZCE9@1386|Bacillus 91061|Bacilli J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA prfA - - ko:K02835 - - - - ko00000,ko03012 - - - PCRF,RF-1 k141_4481_1 42565.FP66_02345 1.21e-167 487.0 COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,1RN3H@1236|Gammaproteobacteria,1XIKC@135619|Oceanospirillales 135619|Oceanospirillales KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance - - 2.7.6.5,3.1.7.2 ko:K01139 ko00230,map00230 - R00336,R00429 RC00002,RC00078 ko00000,ko00001,ko01000,ko03009 - - - ACT_4,HD_4,RelA_SpoT,TGS k141_20097_1 1408424.JHYI01000006_gene228 4.03e-14 72.8 COG1052@1|root,COG1052@2|Bacteria,1TPCX@1239|Firmicutes,4HASY@91061|Bacilli,1ZB0I@1386|Bacillus 91061|Bacilli CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family - - 1.1.1.26 ko:K00015 ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120 - R00717,R01388 RC00031,RC00042 ko00000,ko00001,ko01000 - - - 2-Hacid_dh,2-Hacid_dh_C k141_16419_1 218284.CCDN010000001_gene452 3.63e-92 275.0 COG0546@1|root,COG0546@2|Bacteria,1V6BF@1239|Firmicutes,4HC3F@91061|Bacilli,1ZEAH@1386|Bacillus 91061|Bacilli F haloacid dehalogenase-like hydrolase - - 3.2.2.9 ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 M00034,M00609 R00194,R01401 RC00063,RC00318 ko00000,ko00001,ko00002,ko01000 - - - HAD_2 k141_24782_2 1128421.JAGA01000002_gene938 6.76e-74 230.0 COG0302@1|root,COG0302@2|Bacteria,2NPAT@2323|unclassified Bacteria 2|Bacteria H GTP cyclohydrolase I folE GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 ko:K01495 ko00790,ko01100,map00790,map01100 M00126,M00841,M00842,M00843 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 - - - GTP_cyclohydroI k141_5841_1 1294265.JCM21738_4611 6.98e-13 63.5 COG0245@1|root,COG0245@2|Bacteria,1V3P0@1239|Firmicutes,4HG1X@91061|Bacilli,1ZB1U@1386|Bacillus 91061|Bacilli I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) ispF - 2.7.7.60,4.6.1.12 ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05633,R05637 RC00002,RC01440 ko00000,ko00001,ko00002,ko01000 - - - YgbB k141_31592_1 586416.GZ22_08110 6.11e-106 314.0 COG0207@1|root,COG0207@2|Bacteria,1TSIR@1239|Firmicutes,4H9QS@91061|Bacilli 91061|Bacilli F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis thyA GO:0003674,GO:0003824,GO:0004799,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0032259,GO:0034641,GO:0034654,GO:0042083,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046385,GO:0046483,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 - - - Thymidylat_synt k141_26114_1 1462526.BN990_01832 1.24e-05 48.1 COG4508@1|root,COG4508@2|Bacteria,1V6PI@1239|Firmicutes,4HJBB@91061|Bacilli,4C60A@84406|Virgibacillus 91061|Bacilli S dUTPase - - - - - - - - - - - - dUTPase_2 k141_26114_3 315730.BcerKBAB4_3447 1.44e-26 99.0 2EAAJ@1|root,334EW@2|Bacteria,1VHS4@1239|Firmicutes,4HQYC@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - k141_30431_1 1307437.J139_17892 9.16e-09 62.0 2C17N@1|root,32YZC@2|Bacteria,1NFDT@1224|Proteobacteria,1SEYC@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_3285_1 1121947.AUHK01000011_gene1437 5.06e-08 55.5 COG1132@1|root,COG1132@2|Bacteria,1TPZP@1239|Firmicutes,249WV@186801|Clostridia,22GRH@1570339|Peptoniphilaceae 186801|Clostridia P ABC transporter, ATP-binding protein - - - ko:K06148 - - - - ko00000,ko02000 3.A.1 - - ABC_tran k141_3285_2 1294265.JCM21738_434 5.61e-56 181.0 COG1277@1|root,COG1277@2|Bacteria,1UZYB@1239|Firmicutes,4HEYC@91061|Bacilli,1ZDVJ@1386|Bacillus 91061|Bacilli S ABC-2 family transporter protein - - - ko:K19341 ko02010,map02010 M00762 - - ko00000,ko00001,ko00002,ko02000 3.A.1.132.2 - - ABC2_membrane_2 k141_29490_1 1042377.AFPJ01000052_gene1537 8.58e-110 339.0 COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,1MVI9@1224|Proteobacteria,1RNB0@1236|Gammaproteobacteria,46617@72275|Alteromonadaceae 1236|Gammaproteobacteria D protein involved in exopolysaccharide biosynthesis - - - ko:K16554,ko:K16692 ko05111,map05111 - - - ko00000,ko00001,ko01000,ko01001,ko02000 8.A.3.1 - - AAA_31,CbiA,GNVR,Wzz k141_20098_1 218284.CCDN010000002_gene2057 1.49e-40 136.0 COG3871@1|root,COG3871@2|Bacteria,1V6MX@1239|Firmicutes,4HIYZ@91061|Bacilli,1ZH2Z@1386|Bacillus 91061|Bacilli S general stress protein ydaG - - - - - - - - - - - Putative_PNPOx,Pyrid_ox_like k141_13001_1 1423321.AS29_20390 5.45e-39 142.0 COG0809@1|root,COG0809@2|Bacteria,1UZJW@1239|Firmicutes,4HCRE@91061|Bacilli,1ZCZ2@1386|Bacillus 91061|Bacilli J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) - - 2.4.99.17 ko:K07568 - - - - ko00000,ko01000,ko03016 - - - Queuosine_synth k141_13001_2 218284.CCDN010000007_gene3898 1.24e-38 135.0 COG1028@1|root,COG1028@2|Bacteria,1V0TV@1239|Firmicutes,4HF8Q@91061|Bacilli,1ZCCS@1386|Bacillus 91061|Bacilli IQ Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short k141_9486_1 1160707.AJIK01000007_gene1152 6.86e-57 192.0 COG2309@1|root,COG2309@2|Bacteria,1TP65@1239|Firmicutes,4H9W8@91061|Bacilli,26DRB@186818|Planococcaceae 91061|Bacilli E Leucyl aminopeptidase (Aminopeptidase T) ampS - - ko:K19689 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M29 k141_9486_2 1408424.JHYI01000009_gene4424 4.86e-49 161.0 COG0537@1|root,COG0537@2|Bacteria,1V6UE@1239|Firmicutes,4HJ7C@91061|Bacilli,1ZGZR@1386|Bacillus 91061|Bacilli FG Scavenger mRNA decapping enzyme C-term binding - - - - - - - - - - - - HIT k141_9486_3 714961.BFZC1_09690 4.55e-11 62.4 COG0454@1|root,COG0456@2|Bacteria,1VAYG@1239|Firmicutes,4HKJE@91061|Bacilli,3IY7S@400634|Lysinibacillus 91061|Bacilli K acetyltransferase - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_4 k141_20099_1 1122602.ATXP01000014_gene1399 2.51e-31 124.0 COG0530@1|root,COG0530@2|Bacteria,2GJR3@201174|Actinobacteria,1W8AC@1268|Micrococcaceae 201174|Actinobacteria P Sodium/calcium exchanger protein - - - ko:K07301 - - - - ko00000,ko02000 2.A.19.5 - - Na_Ca_ex k141_16420_1 1294265.JCM21738_2697 1.84e-107 322.0 COG0366@1|root,COG0366@2|Bacteria,1TSVI@1239|Firmicutes,4HCV2@91061|Bacilli,1ZDR6@1386|Bacillus 91061|Bacilli G Alpha amylase, catalytic domain - - 3.2.1.1 ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 - R02108,R02112,R11262 - ko00000,ko00001,ko01000 - GH13 - Alpha-amylase k141_2033_1 218284.CCDN010000007_gene4001 4.12e-243 674.0 COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,4HAT6@91061|Bacilli,1ZB62@1386|Bacillus 91061|Bacilli C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits atpD - 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - iSB619.SA_RS10965 ATP-synt_ab,ATP-synt_ab_N k141_4484_1 218284.CCDN010000006_gene3664 1.3e-93 281.0 2DBB1@1|root,2Z854@2|Bacteria,1TT9P@1239|Firmicutes,4HDSP@91061|Bacilli,1ZEVA@1386|Bacillus 91061|Bacilli S Domain of Unknown Function (DUF1206) - - - - - - - - - - - - DUF1206 k141_22514_1 1116375.VEJY3_00175 3.89e-187 549.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1XSSQ@135623|Vibrionales 135623|Vibrionales V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K18138 ko01501,ko01503,map01501,map01503 M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2 - - ACR_tran k141_22514_2 1116375.VEJY3_00170 7.75e-40 133.0 COG2960@1|root,COG2960@2|Bacteria,1N7AH@1224|Proteobacteria,1SCH1@1236|Gammaproteobacteria,1XYA8@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria yqiC - - ko:K09806 - - - - ko00000 - - - BMFP k141_29492_1 1307436.PBF_07206 2.23e-75 232.0 COG0631@1|root,COG0631@2|Bacteria,1V6K5@1239|Firmicutes,4HCDR@91061|Bacilli,1ZCYC@1386|Bacillus 91061|Bacilli T phosphatase stp - 3.1.3.16 ko:K20074 - - - - ko00000,ko01000,ko01009 - - - PP2C,PP2C_2 k141_29492_2 1294265.JCM21738_242 2.34e-63 197.0 COG0820@1|root,COG0820@2|Bacteria,1TPVF@1239|Firmicutes,4H9NU@91061|Bacilli,1ZBCJ@1386|Bacillus 91061|Bacilli J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs rlmN GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 ko:K06941 - - - - ko00000,ko01000,ko03009 - - - Fer4_14,Radical_SAM k141_17492_1 1116375.VEJY3_00960 7.62e-254 712.0 COG4775@1|root,COG4775@2|Bacteria,1MX3H@1224|Proteobacteria,1RQKV@1236|Gammaproteobacteria,1XSM5@135623|Vibrionales 135623|Vibrionales M Exopolysaccharide biosynthesis protein YbjH wbfB - - - - - - - - - - - YjbH k141_17492_2 1116375.VEJY3_00955 2.49e-228 628.0 COG0451@1|root,COG0451@2|Bacteria,1MVE4@1224|Proteobacteria,1RP2S@1236|Gammaproteobacteria,1XTH4@135623|Vibrionales 135623|Vibrionales GM Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose hldD GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008712,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016853,GO:0016854,GO:0016857,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0046401,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 5.1.3.20 ko:K03274 ko00540,ko01100,map00540,map01100 M00064 R05176 RC01291 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Epimerase k141_17492_3 1116375.VEJY3_00950 4.95e-170 479.0 COG1560@1|root,COG1560@2|Bacteria,1N9ZJ@1224|Proteobacteria,1RRI7@1236|Gammaproteobacteria,1XTMN@135623|Vibrionales 135623|Vibrionales M Catalyzes the transfer of myristate from myristoyl-acyl carrier protein (ACP) to Kdo(2)-(lauroyl)-lipid IV(A) to form Kdo(2)-lipid A lpxM - 2.3.1.243 ko:K02560 ko00540,ko01100,map00540,map01100 M00060 R05075 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Lip_A_acyltrans k141_35570_1 1463825.JNXC01000040_gene5232 2.46e-48 176.0 COG3209@1|root,COG4733@1|root,COG3209@2|Bacteria,COG4733@2|Bacteria,2GK1D@201174|Actinobacteria,4EABX@85010|Pseudonocardiales 201174|Actinobacteria M Insecticide toxin TcdB middle/N-terminal region - - - - - - - - - - - - PT-HINT,RHS_repeat,SpvB,TcdB_toxin_midN k141_28111_1 1178482.BJB45_11000 4.32e-23 96.7 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,1RNAM@1236|Gammaproteobacteria 1236|Gammaproteobacteria G TRAP-type C4-dicarboxylate transport system, large permease component - - - - - - - - - - - - DctM k141_28111_2 1121943.KB899997_gene1707 2.56e-64 210.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RP59@1236|Gammaproteobacteria 1236|Gammaproteobacteria C belongs to the aldehyde dehydrogenase family - - 1.2.1.3 ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_36434_14 1279017.AQYJ01000026_gene212 1.65e-120 347.0 COG4122@1|root,COG4122@2|Bacteria,1N2AR@1224|Proteobacteria,1S16T@1236|Gammaproteobacteria,4671N@72275|Alteromonadaceae 1236|Gammaproteobacteria S Methyltransferase domain - - - - - - - - - - - - Methyltransf_24 k141_36434_15 1279017.AQYJ01000026_gene211 2.78e-134 384.0 COG0110@1|root,COG0110@2|Bacteria,1N6SQ@1224|Proteobacteria,1SYWK@1236|Gammaproteobacteria,46CWF@72275|Alteromonadaceae 1236|Gammaproteobacteria S Hexapeptide repeat of succinyl-transferase - - 2.3.1.79 ko:K00661 - - - - ko00000,ko01000 - - - Hexapep,Hexapep_2,Mac k141_36434_16 1042377.AFPJ01000019_gene2524 3.89e-90 267.0 COG0703@1|root,COG0703@2|Bacteria,1MUFJ@1224|Proteobacteria,1S65E@1236|Gammaproteobacteria,467Q3@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate aroK - 2.7.1.71 ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - SKI k141_36434_18 1279017.AQYJ01000026_gene208 0.0 1991.0 COG1014@1|root,COG4231@1|root,COG1014@2|Bacteria,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,1RSEQ@1236|Gammaproteobacteria,465RF@72275|Alteromonadaceae 1236|Gammaproteobacteria C Pyruvate ferredoxin/flavodoxin oxidoreductase - - 1.2.7.8 ko:K04090 - - - - br01601,ko00000,ko01000 - - - POR,TPP_enzyme_C k141_36434_19 1453501.JELR01000001_gene2037 3.26e-193 548.0 COG3746@1|root,COG3746@2|Bacteria,1RG6T@1224|Proteobacteria,1S412@1236|Gammaproteobacteria,468U6@72275|Alteromonadaceae 1236|Gammaproteobacteria P Phosphate-selective porin O and P oprO - - ko:K07221 - - - - ko00000,ko02000 1.B.5.1 - - Porin_O_P k141_36434_20 1042377.AFPJ01000019_gene2520 5.7e-103 310.0 COG3735@1|root,COG3735@2|Bacteria,1MVCW@1224|Proteobacteria,1RRI8@1236|Gammaproteobacteria,4659X@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria ybaP - - ko:K09973 - - - - ko00000 - - - TraB k141_36434_21 1042377.AFPJ01000019_gene2519 9.78e-94 291.0 COG0438@1|root,COG0438@2|Bacteria,1MUTA@1224|Proteobacteria,1RS31@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Glycosyl transferase - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 k141_36434_22 1453501.JELR01000001_gene2040 4.63e-112 337.0 COG0438@1|root,COG0438@2|Bacteria,1RKCN@1224|Proteobacteria,1S4CE@1236|Gammaproteobacteria,46BAR@72275|Alteromonadaceae 1236|Gammaproteobacteria M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 k141_36434_23 1279017.AQYJ01000026_gene204 1.35e-69 216.0 COG3637@1|root,COG3637@2|Bacteria,1N7IC@1224|Proteobacteria 1224|Proteobacteria M Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - ko:K12976 - - - - ko00000,ko01000,ko01005 - - - PagL k141_36434_24 1279017.AQYJ01000026_gene203 1.84e-205 578.0 COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,1RMQI@1236|Gammaproteobacteria,464VE@72275|Alteromonadaceae 1236|Gammaproteobacteria K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth - - - - - - - - - - - - Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 k141_36434_25 561175.KB894095_gene2558 0.000616 47.4 COG2353@1|root,COG2353@2|Bacteria,2IG0K@201174|Actinobacteria 201174|Actinobacteria S Belongs to the UPF0312 family - - - - - - - - - - - - YceI k141_36434_28 1122134.KB893650_gene1192 4.6e-59 185.0 COG0346@1|root,COG0346@2|Bacteria,1RHM9@1224|Proteobacteria,1S6Y3@1236|Gammaproteobacteria,1XPDH@135619|Oceanospirillales 135619|Oceanospirillales E PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - - - - - - - - - - Glyoxalase k141_36434_29 1279017.AQYJ01000026_gene200 4.44e-141 402.0 COG1028@1|root,COG1028@2|Bacteria,1MWBC@1224|Proteobacteria,1RNNV@1236|Gammaproteobacteria,46407@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) yciK GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0008150,GO:0008152,GO:0009056,GO:0016491,GO:0044464,GO:0055114,GO:0071704,GO:1901575 - - - - - - - - - - adh_short k141_36434_30 1042377.AFPJ01000019_gene2506 4.39e-124 357.0 COG0546@1|root,COG0546@2|Bacteria,1RCXJ@1224|Proteobacteria,1S3VU@1236|Gammaproteobacteria,4674M@72275|Alteromonadaceae 1236|Gammaproteobacteria S HAD-hyrolase-like gph GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006040,GO:0006082,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008967,GO:0009254,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019752,GO:0030203,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097172,GO:1901135,GO:1901360,GO:1901564 3.1.3.105,3.1.3.18 ko:K01091,ko:K22292 ko00520,ko00630,ko01100,ko01110,ko01130,map00520,map00630,map01100,map01110,map01130 - R01334,R11785 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 k141_36434_31 1042377.AFPJ01000019_gene2505 1.51e-146 415.0 COG2227@1|root,COG2227@2|Bacteria,1MU89@1224|Proteobacteria,1RMV7@1236|Gammaproteobacteria,464RA@72275|Alteromonadaceae 1236|Gammaproteobacteria H O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway ubiG GO:0003674,GO:0003824,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008289,GO:0008689,GO:0008757,GO:0009058,GO:0009108,GO:0009628,GO:0009651,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0042180,GO:0042181,GO:0042538,GO:0043167,GO:0043168,GO:0043431,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0051188,GO:0061542,GO:0071704,GO:1901576,GO:1901611,GO:1901661,GO:1901663 2.1.1.222,2.1.1.64 ko:K00568 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04988,R05614,R08769,R08781 RC00003,RC00392,RC01895 ko00000,ko00001,ko00002,ko01000 - - iE2348C_1286.E2348C_2376 Methyltransf_23 k141_36434_32 1279017.AQYJ01000026_gene197 1.29e-243 678.0 COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,1RN13@1236|Gammaproteobacteria,465K9@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine mtaD - 3.5.4.28,3.5.4.31 ko:K12960 ko00270,ko01100,map00270,map01100 - R09660 RC00477 ko00000,ko00001,ko01000 - - - Amidohydro_1 k141_36434_33 1279017.AQYJ01000026_gene196 0.0 1429.0 COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,1RN03@1236|Gammaproteobacteria,4643E@72275|Alteromonadaceae 1236|Gammaproteobacteria L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrA GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0018130,GO:0019438,GO:0032774,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042493,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097659,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 5.99.1.3 ko:K02469 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseA_C,DNA_topoisoIV k141_37716_1 42565.FP66_07885 4.06e-33 115.0 2CDSW@1|root,330PB@2|Bacteria,1NEYD@1224|Proteobacteria,1SFQC@1236|Gammaproteobacteria,1XM9A@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_37716_2 42565.FP66_07880 9.48e-65 197.0 2F9QS@1|root,3420W@2|Bacteria,1NZEJ@1224|Proteobacteria,1SQQ0@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_3301_1 981085.XP_010088796.1 1.93e-23 104.0 COG1404@1|root,2QZDA@2759|Eukaryota,37QS2@33090|Viridiplantae,3GD1X@35493|Streptophyta,4JG4V@91835|fabids 35493|Streptophyta O subtilisin-like protease - GO:0001763,GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005773,GO:0005774,GO:0006508,GO:0006807,GO:0007275,GO:0007568,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009505,GO:0009653,GO:0010016,GO:0010150,GO:0010223,GO:0010346,GO:0016020,GO:0016787,GO:0017171,GO:0019538,GO:0030312,GO:0031090,GO:0032501,GO:0032502,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044422,GO:0044424,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0048046,GO:0048366,GO:0048367,GO:0048646,GO:0048731,GO:0048827,GO:0048856,GO:0070011,GO:0071704,GO:0071944,GO:0090693,GO:0098588,GO:0098805,GO:0099402,GO:0140096,GO:1901564,GO:1905393 - - - - - - - - - - Inhibitor_I9,PA,Peptidase_S8 k141_30450_2 1453501.JELR01000002_gene644 7.87e-60 188.0 COG1777@1|root,COG1777@2|Bacteria,1N78A@1224|Proteobacteria,1SDX8@1236|Gammaproteobacteria 1236|Gammaproteobacteria K ROK family - - - - - - - - - - - - - k141_30450_3 1117647.M5M_06210 3.1e-240 667.0 COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,1RS1D@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Creatinase/Prolidase N-terminal domain - - 3.4.13.9 ko:K01271 - - - - ko00000,ko01000,ko01002 - - - Creatinase_N,Peptidase_M24 k141_30450_4 1453501.JELR01000002_gene643 2.03e-125 364.0 COG0384@1|root,COG0384@2|Bacteria,1R9X4@1224|Proteobacteria,1RZ0R@1236|Gammaproteobacteria,466E6@72275|Alteromonadaceae 1236|Gammaproteobacteria S epimerase, PhzC PhzF homolog yddE_1 - - - - - - - - - - - PhzC-PhzF k141_10529_1 1121943.KB899997_gene1759 8.22e-122 360.0 COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,1RMGJ@1236|Gammaproteobacteria,1XI9F@135619|Oceanospirillales 135619|Oceanospirillales Q COG1233 Phytoene dehydrogenase and related proteins - - 1.3.99.23 ko:K09516 ko00830,map00830 - R07163 RC01835 ko00000,ko00001,ko01000 - - - Amino_oxidase,NAD_binding_8 k141_10529_2 1479235.KK366039_gene2986 1.09e-34 128.0 COG0654@1|root,COG0654@2|Bacteria,1N8DE@1224|Proteobacteria,1S5UK@1236|Gammaproteobacteria 1236|Gammaproteobacteria CH lycopene cyclase crtY - 5.5.1.19 ko:K06443 ko00906,ko01100,ko01110,map00906,map01100,map01110 M00097 R03824,R04801,R05341,R06962,R07856 RC01004,RC01964 ko00000,ko00001,ko00002,ko01000 - - - Lycopene_cycl k141_16448_1 1294265.JCM21738_156 1.55e-136 395.0 COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,4HA13@91061|Bacilli,1ZCMB@1386|Bacillus 91061|Bacilli E Aminotransferase aspB GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769,GO:0047297 2.6.1.1,2.6.1.14 ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 - R00355,R00694,R00734,R00896,R01346,R02433,R02619,R05052 RC00006,RC00025 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 k141_16448_2 1294265.JCM21738_157 3.56e-46 154.0 COG3935@1|root,COG3935@2|Bacteria,1V283@1239|Firmicutes,4HFP3@91061|Bacilli,1ZC34@1386|Bacillus 91061|Bacilli L DNA replication protein DnaD dnaD - - ko:K02086 - - - - ko00000 - - - DnaB_2,HTH_36 k141_37717_1 218284.CCDN010000001_gene682 1.45e-58 192.0 COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,4HA6H@91061|Bacilli,1ZB1B@1386|Bacillus 91061|Bacilli E Cysteine desulfurase iscS - 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - - Aminotran_5 k141_17537_1 1042377.AFPJ01000028_gene2179 9.11e-92 275.0 COG1218@1|root,COG1218@2|Bacteria,1N0GY@1224|Proteobacteria,1RP5A@1236|Gammaproteobacteria,4642N@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1218 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase cysQ - 3.1.3.7 ko:K01082 ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130 - R00188,R00508 RC00078 ko00000,ko00001,ko01000,ko03016 - - - Inositol_P k141_22564_1 1279017.AQYJ01000025_gene491 1.08e-46 156.0 COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria 1224|Proteobacteria C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine nrdG - 1.97.1.4 ko:K04069 - - R04710 - ko00000,ko01000 - - - Fer4_12,Radical_SAM k141_22564_2 1279017.AQYJ01000024_gene856 9.09e-162 466.0 COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,1RND5@1236|Gammaproteobacteria,464ZN@72275|Alteromonadaceae 1236|Gammaproteobacteria CH COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - ko:K03185,ko:K18800 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04987,R04989,R08768,R08773 RC00046,RC02670 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_3 k141_22564_3 1279017.AQYJ01000027_gene1678 2.44e-130 372.0 COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,1RSY6@1236|Gammaproteobacteria,466D6@72275|Alteromonadaceae 1236|Gammaproteobacteria P Reversible hydration of carbon dioxide - - 4.2.1.1 ko:K01673 ko00910,map00910 - R00132,R10092 RC02807 ko00000,ko00001,ko01000 - - - Pro_CA k141_22564_4 1121935.AQXX01000115_gene5013 1.34e-23 99.8 COG0760@1|root,COG0760@2|Bacteria,1RDD3@1224|Proteobacteria,1S2D7@1236|Gammaproteobacteria,1XRIB@135619|Oceanospirillales 135619|Oceanospirillales O PPIC-type PPIASE domain - - 5.2.1.8 ko:K03769 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_3 k141_7170_1 218284.CCDN010000001_gene1064 2.49e-121 362.0 COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HBZ0@91061|Bacilli,1ZAQC@1386|Bacillus 91061|Bacilli T Histidine kinase resE - 2.7.13.3 ko:K07651 ko02020,map02020 M00458 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,PAS,PAS_4 k141_29764_1 1235279.C772_02284 3.54e-38 134.0 2DTDS@1|root,33JWR@2|Bacteria,1VSIJ@1239|Firmicutes,4HUX2@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF2711) - - - - - - - - - - - - DUF2711 k141_29764_2 866895.HBHAL_2610 9.54e-67 204.0 COG0346@1|root,COG0346@2|Bacteria,1V6KX@1239|Firmicutes,4HJMS@91061|Bacilli 91061|Bacilli E Lactoylglutathione lyase and related lyases yqjT - - - - - - - - - - - Glyoxalase,Glyoxalase_4 k141_80_1 1318628.MARLIPOL_04600 4.16e-54 192.0 2C593@1|root,2Z84R@2|Bacteria,1Q8PC@1224|Proteobacteria,1RP26@1236|Gammaproteobacteria,46680@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_22661_1 742738.HMPREF9460_03883 6.71e-05 49.3 COG2755@1|root,COG2755@2|Bacteria,1VDE2@1239|Firmicutes,24N6X@186801|Clostridia,269IA@186813|unclassified Clostridiales 186801|Clostridia E GDSL-like Lipase/Acylhydrolase - - - - - - - - - - - - Lipase_GDSL_2 k141_3636_2 218284.CCDN010000001_gene32 8.71e-115 335.0 COG1760@1|root,COG1760@2|Bacteria,1TP79@1239|Firmicutes,4HAI1@91061|Bacilli,1ZC9A@1386|Bacillus 91061|Bacilli E L-serine dehydratase sdaAA GO:0003674,GO:0003824,GO:0003941,GO:0016829,GO:0016840,GO:0016841 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 - R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 - - - SDH_alpha k141_28602_1 218284.CCDN010000008_gene4137 2.19e-193 557.0 COG0058@1|root,COG0058@2|Bacteria,1TQAJ@1239|Firmicutes,4H9XI@91061|Bacilli,1ZCRF@1386|Bacillus 91061|Bacilli G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties glgP GO:0000272,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005976,GO:0005977,GO:0005980,GO:0006073,GO:0006091,GO:0006112,GO:0008144,GO:0008150,GO:0008152,GO:0008184,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0015980,GO:0016052,GO:0016740,GO:0016757,GO:0016758,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901575 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 - R02111 - ko00000,ko00001,ko01000 - GT35 iYO844.BSU30940 Phosphorylase k141_14328_1 997346.HMPREF9374_3630 2.24e-48 166.0 COG0492@1|root,COG0492@2|Bacteria,1TRPN@1239|Firmicutes,4H9V7@91061|Bacilli,27B9T@186824|Thermoactinomycetaceae 91061|Bacilli O Pyridine nucleotide-disulphide oxidoreductase trxB5 - 1.18.1.2,1.19.1.1 ko:K21567 - - - - ko00000,ko01000 - - - Pyr_redox_2 k141_23816_1 1279017.AQYJ01000029_gene3824 1.59e-114 332.0 COG2915@1|root,COG2915@2|Bacteria,1RI8B@1224|Proteobacteria,1RPCC@1236|Gammaproteobacteria,467AZ@72275|Alteromonadaceae 1236|Gammaproteobacteria S High frequency lysogenization protein HflD homolog hflD GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009898,GO:0016020,GO:0019897,GO:0019898,GO:0031234,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0071944,GO:0098552,GO:0098562 - ko:K07153 - - - - ko00000 - - - DUF489 k141_23816_2 1279017.AQYJ01000029_gene3825 1.58e-248 685.0 COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,1RMAK@1236|Gammaproteobacteria,464B7@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 mnmA GO:0001510,GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0003824,GO:0004808,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016782,GO:0016783,GO:0030488,GO:0032259,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.8.1.13 ko:K00566 ko04122,map04122 - R08700 RC02313,RC02315 ko00000,ko00001,ko01000,ko03016 - - - tRNA_Me_trans k141_23816_3 626887.J057_20095 1.5e-85 258.0 COG1187@1|root,COG1187@2|Bacteria,1R9VV@1224|Proteobacteria,1S1ZX@1236|Gammaproteobacteria,466JR@72275|Alteromonadaceae 1236|Gammaproteobacteria J Belongs to the pseudouridine synthase RsuA family rluE GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.20 ko:K06181 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2 k141_23816_4 1279017.AQYJ01000029_gene3827 1.69e-294 804.0 COG0538@1|root,COG0538@2|Bacteria,1MW3J@1224|Proteobacteria,1RNMD@1236|Gammaproteobacteria,46DBZ@72275|Alteromonadaceae 1236|Gammaproteobacteria C Isocitrate/isopropylmalate dehydrogenase icd GO:0003674,GO:0003824,GO:0004448,GO:0004450,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0022900,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0055114 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 - - e_coli_core.b1136,iAF1260.b1136,iECDH1ME8569_1439.ECDH1ME8569_1071,iEcDH1_1363.EcDH1_2511,iJN746.PP_4011,iJO1366.b1136,iJR904.b1136,iY75_1357.Y75_RS05930,iYL1228.KPN_01144 Iso_dh k141_23816_5 1279017.AQYJ01000029_gene3828 3.51e-43 142.0 COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,468RS@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG1278 Cold shock proteins cspD GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006275,GO:0006355,GO:0006950,GO:0008150,GO:0008156,GO:0009266,GO:0009409,GO:0009605,GO:0009628,GO:0009889,GO:0009890,GO:0009892,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031667,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2000113,GO:2001141 - ko:K03704 - - - - ko00000,ko03000 - - - CSD k141_23816_6 498211.CJA_2569 3.51e-49 160.0 COG2127@1|root,COG2127@2|Bacteria,1MZU8@1224|Proteobacteria,1S8Z7@1236|Gammaproteobacteria,1FHHY@10|Cellvibrio 1236|Gammaproteobacteria S Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation clpS GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0050896,GO:0051087 - ko:K06891 - - - - ko00000 - - - ClpS k141_23816_7 1279017.AQYJ01000029_gene3830 0.0 1351.0 COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,1RMH3@1236|Gammaproteobacteria,464M6@72275|Alteromonadaceae 1236|Gammaproteobacteria O Belongs to the ClpA ClpB family clpA GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043335,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 - ko:K03694 - - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N k141_23816_8 1415778.JQMM01000001_gene1748 5.83e-42 139.0 COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,1S8WZ@1236|Gammaproteobacteria,1J6G9@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex infA GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02518 - - - - ko00000,ko03012 - - - eIF-1a k141_23816_9 1279017.AQYJ01000029_gene3832 5.53e-154 434.0 COG2935@1|root,COG2935@2|Bacteria,1MW62@1224|Proteobacteria,1RYD7@1236|Gammaproteobacteria,465QZ@72275|Alteromonadaceae 1236|Gammaproteobacteria O May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate ate GO:0003674,GO:0003824,GO:0004057,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016598,GO:0016740,GO:0016746,GO:0016755,GO:0019538,GO:0019941,GO:0030163,GO:0036211,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 2.3.2.29 ko:K21420 - - R11547,R11548 RC00064 ko00000,ko01000 - - - ATE_C,ATE_N k141_23816_10 1279017.AQYJ01000029_gene3833 2.53e-126 364.0 COG2360@1|root,COG2360@2|Bacteria,1R9W8@1224|Proteobacteria,1S1ZB@1236|Gammaproteobacteria,466EF@72275|Alteromonadaceae 1236|Gammaproteobacteria O Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine aat GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.3.2.6 ko:K00684 - - R03813,R11443,R11444 RC00055,RC00064 ko00000,ko01000 - - - Leu_Phe_trans k141_34535_2 1089548.KI783301_gene1570 1.59e-119 351.0 COG0351@1|root,COG0351@2|Bacteria,1TQ4A@1239|Firmicutes,4HAAH@91061|Bacilli,3WEMK@539002|Bacillales incertae sedis 91061|Bacilli H Phosphomethylpyrimidine kinase thiD - 2.7.1.49,2.7.4.7 ko:K00941 ko00730,ko01100,map00730,map01100 M00127 R03471,R04509 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Phos_pyr_kin k141_33341_2 218284.CCDN010000001_gene1544 1.83e-18 84.0 COG1686@1|root,COG1686@2|Bacteria,1TQN0@1239|Firmicutes,4HBD4@91061|Bacilli,1ZAS6@1386|Bacillus 91061|Bacilli M Belongs to the peptidase S11 family dacA GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0009002,GO:0016787,GO:0017171,GO:0019538,GO:0030312,GO:0043170,GO:0044238,GO:0044464,GO:0070008,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.16.4 ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - PBP5_C,Peptidase_S11 k141_2454_1 1294265.JCM21738_2535 1.47e-27 105.0 COG0671@1|root,COG0671@2|Bacteria,1VF2U@1239|Firmicutes,4HNXR@91061|Bacilli,1ZIEP@1386|Bacillus 91061|Bacilli I COG0671 Membrane-associated phospholipid phosphatase pgpB3 - 3.6.1.27 ko:K19302 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - PAP2 k141_2454_2 1294265.JCM21738_2533 1.18e-67 217.0 COG1004@1|root,COG1004@2|Bacteria,1TQFN@1239|Firmicutes,4HADP@91061|Bacilli,1ZAP3@1386|Bacillus 91061|Bacilli M Belongs to the UDP-glucose GDP-mannose dehydrogenase family - - 1.1.1.22 ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 M00014,M00129,M00361,M00362 R00286 RC00291 ko00000,ko00001,ko00002,ko01000 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N k141_4830_1 218284.CCDN010000004_gene3156 1.33e-105 312.0 COG0561@1|root,COG0561@2|Bacteria,1V2XI@1239|Firmicutes,4HG2U@91061|Bacilli,1ZB1F@1386|Bacillus 91061|Bacilli S hydrolases of the HAD superfamily yhaX - - - - - - - - - - - Hydrolase_3 k141_35724_1 1042377.AFPJ01000036_gene1168 1.79e-209 592.0 COG1680@1|root,COG1680@2|Bacteria,1MY4Y@1224|Proteobacteria,1RY1C@1236|Gammaproteobacteria,466BA@72275|Alteromonadaceae 1236|Gammaproteobacteria V Beta-lactamase - - - - - - - - - - - - Beta-lactamase k141_35724_2 156578.ATW7_08054 3.03e-65 210.0 COG4464@1|root,COG4464@2|Bacteria,1R5E2@1224|Proteobacteria,1S34B@1236|Gammaproteobacteria 1236|Gammaproteobacteria GM capsular polysaccharide biosynthesis protein ywqE - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - - k141_35724_3 1042377.AFPJ01000055_gene972 1.29e-277 800.0 COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,1MVI9@1224|Proteobacteria,1RNB0@1236|Gammaproteobacteria,4649B@72275|Alteromonadaceae 1236|Gammaproteobacteria D COG0489 ATPases involved in chromosome partitioning - - - ko:K16554 ko05111,map05111 - - - ko00000,ko00001,ko02000 8.A.3.1 - - AAA_31,CbiA,GNVR,Wzz k141_35724_4 1042377.AFPJ01000052_gene1538 6.73e-61 194.0 COG1596@1|root,COG1596@2|Bacteria,1MXYS@1224|Proteobacteria,1SC60@1236|Gammaproteobacteria,467H9@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG1596 Periplasmic protein involved in polysaccharide export gumB - - ko:K20988 ko05111,map05111 - - - ko00000,ko00001,ko02000 1.B.18 - - Poly_export,SLBB k141_35724_5 1120970.AUBZ01000019_gene3545 9.51e-44 164.0 COG5338@1|root,COG5338@2|Bacteria,1R56M@1224|Proteobacteria,1S0PC@1236|Gammaproteobacteria,464BC@72275|Alteromonadaceae 1236|Gammaproteobacteria S Putative beta-barrel porin 2 - - - ko:K20920 ko05111,map05111 - - - ko00000,ko00001,ko02000 1.B.66.3.1,1.B.66.3.2 - - BBP2_2 k141_35724_6 1042377.AFPJ01000055_gene969 2.27e-222 626.0 COG2148@1|root,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,1RMMN@1236|Gammaproteobacteria,46597@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG2148 Sugar transferases involved in lipopolysaccharide synthesis wcaJ - - ko:K03606 ko05111,map05111 - - - ko00000,ko00001 - - - Bac_transf,CoA_binding_3 k141_35724_8 1173028.ANKO01000086_gene4 4.46e-21 96.3 COG2091@1|root,COG2091@2|Bacteria,1G5GA@1117|Cyanobacteria,1HAPE@1150|Oscillatoriales 1117|Cyanobacteria H Belongs to the P-Pant transferase superfamily hetI GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008897,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016780,GO:0019752,GO:0019878,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - ko:K06133 ko00770,map00770 - R01625 RC00002 ko00000,ko00001,ko01000 - - - ACPS k141_35724_10 1042377.AFPJ01000055_gene967 2.8e-143 428.0 COG0367@1|root,COG0367@2|Bacteria,1NDEB@1224|Proteobacteria,1SDZJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria E asparagine synthase - - - - - - - - - - - - - k141_35724_11 1042377.AFPJ01000055_gene966 5.2e-175 507.0 COG2244@1|root,COG2244@2|Bacteria 2|Bacteria S polysaccharide biosynthetic process - - - ko:K03328 - - - - ko00000 2.A.66.2 - - Polysacc_synt_3 k141_35724_12 1317118.ATO8_08391 4.44e-35 126.0 COG0707@1|root,COG0707@2|Bacteria,1RJH9@1224|Proteobacteria,2UCZ1@28211|Alphaproteobacteria,4KNWU@93682|Roseivivax 28211|Alphaproteobacteria M Oligosaccharide biosynthesis protein Alg14 like pssD - - - - - - - - - - - Alg14 k141_35724_13 1248916.ANFY01000003_gene532 6.81e-29 111.0 COG5017@1|root,COG5017@2|Bacteria,1MZGV@1224|Proteobacteria,2UBWE@28211|Alphaproteobacteria,2K671@204457|Sphingomonadales 204457|Sphingomonadales S Glycosyltransferase family 28 C-terminal domain - - - - - - - - - - - - Glyco_tran_28_C k141_30983_1 218284.CCDN010000001_gene655 5.39e-55 174.0 2E8Q1@1|root,33314@2|Bacteria,1VFPE@1239|Firmicutes,4HPJ2@91061|Bacilli,1ZHSS@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3792) yrzE - - - - - - - - - - - DUF3792 k141_13197_1 1123053.AUDG01000055_gene2205 1.01e-114 342.0 COG3844@1|root,COG3844@2|Bacteria,1MUKN@1224|Proteobacteria,1RPY3@1236|Gammaproteobacteria,1X2Q3@135613|Chromatiales 135613|Chromatiales E Aminotransferase class-V - - - - - - - - - - - - Aminotran_5 k141_31015_1 1033734.CAET01000045_gene585 3.02e-31 126.0 COG2905@1|root,COG2905@2|Bacteria,1TQFI@1239|Firmicutes,4HCIW@91061|Bacilli,1ZCEI@1386|Bacillus 91061|Bacilli T Putative nucleotidyltransferase substrate binding domain - - - ko:K07182 - - - - ko00000 - - - CBS,DUF294,DUF294_C,cNMP_binding k141_6059_1 42565.FP66_07375 1.83e-92 272.0 COG0450@1|root,COG0450@2|Bacteria,1MWPY@1224|Proteobacteria,1RN4S@1236|Gammaproteobacteria,1XH9F@135619|Oceanospirillales 135619|Oceanospirillales O Alkyl hydroperoxide reductase - - 1.11.1.15 ko:K03386 ko04214,map04214 - - - ko00000,ko00001,ko01000,ko04147 - - - 1-cysPrx_C,AhpC-TSA k141_6059_2 1238190.AMQY01000025_gene61 8.46e-15 72.8 COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,1RMEX@1236|Gammaproteobacteria,1XH75@135619|Oceanospirillales 135619|Oceanospirillales C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family trxB - 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Pyr_redox_2 k141_14368_1 935845.JADQ01000064_gene81 9.39e-05 44.3 COG0842@1|root,COG0842@2|Bacteria,1TQG7@1239|Firmicutes,4H9MK@91061|Bacilli,26SM3@186822|Paenibacillaceae 91061|Bacilli V ABC transporter permease - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane,ABC2_membrane_3 k141_14368_2 1294265.JCM21738_1796 1.78e-81 249.0 COG1131@1|root,COG1131@2|Bacteria,1TQKM@1239|Firmicutes,4HBUK@91061|Bacilli,1ZDAX@1386|Bacillus 91061|Bacilli V COG1131 ABC-type multidrug transport system, ATPase component ybhF_2 - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_15563_1 218284.CCDN010000001_gene1014 2.12e-205 572.0 COG0491@1|root,COG0491@2|Bacteria,1TQPX@1239|Firmicutes,4HAV6@91061|Bacilli,1ZCFS@1386|Bacillus 91061|Bacilli S COG0491 Zn-dependent hydrolases, including glyoxylases yqjP - - - - - - - - - - - Lactamase_B k141_28644_1 1453501.JELR01000002_gene1139 2.01e-57 188.0 COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,1RREX@1236|Gammaproteobacteria,4666W@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit pdhA - 1.2.4.1 ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh k141_23838_1 1036674.A28LD_0326 8.76e-30 120.0 COG3544@1|root,COG3544@2|Bacteria,1N0KY@1224|Proteobacteria,1SBTF@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF305) - - - - - - - - - - - - DUF305 k141_1237_1 218284.CCDN010000001_gene1039 6.59e-97 291.0 COG1015@1|root,COG1015@2|Bacteria,1TP70@1239|Firmicutes,4H9RU@91061|Bacilli,1ZBG0@1386|Bacillus 91061|Bacilli G Phosphotransfer between the C1 and C5 carbon atoms of pentose deoB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008973,GO:0009987,GO:0016853,GO:0016866,GO:0016868,GO:0034641,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360 5.4.2.7 ko:K01839 ko00030,ko00230,map00030,map00230 - R01057,R02749 RC00408 ko00000,ko00001,ko01000 - - - Metalloenzyme k141_33370_1 42565.FP66_07065 3.18e-113 359.0 COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,1RN2W@1236|Gammaproteobacteria,1XHTM@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate gltB - 1.4.1.13,1.4.1.14 ko:K00265 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - GATase_2,GXGXG,Glu_syn_central,Glu_synthase k141_118_2 218284.CCDN010000011_gene4401 2.36e-153 432.0 COG1214@1|root,COG1214@2|Bacteria,1V4YX@1239|Firmicutes,4HHD7@91061|Bacilli,1ZC43@1386|Bacillus 91061|Bacilli O COG1214 Inactive homolog of metal-dependent proteases yeaZ GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 ko:K01409,ko:K14742 - - R10648 RC00070,RC00416 ko00000,ko01000,ko03016 - - - Peptidase_M22 k141_21520_1 218284.CCDN010000002_gene2685 2.37e-68 223.0 COG3211@1|root,COG3211@2|Bacteria,1UYPE@1239|Firmicutes,4HCRC@91061|Bacilli,1ZDBG@1386|Bacillus 91061|Bacilli N Bacterial protein of unknown function (DUF839) - - - ko:K07093 - - - - ko00000 - - - DUF839 k141_21520_2 218284.CCDN010000002_gene2686 1.77e-13 66.6 COG0590@1|root,COG0590@2|Bacteria,1V5NR@1239|Firmicutes,4HH7Q@91061|Bacilli,1ZGB6@1386|Bacillus 91061|Bacilli FJ MafB19-like deaminase - - - - - - - - - - - - MafB19-deam,dCMP_cyt_deam_1 k141_31016_1 218284.CCDN010000001_gene539 1.44e-114 346.0 COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,4HABZ@91061|Bacilli,1ZB5W@1386|Bacillus 91061|Bacilli J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) thrS GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD k141_25028_2 1042377.AFPJ01000007_gene1877 9.83e-94 277.0 COG3038@1|root,COG3038@2|Bacteria,1MZ7X@1224|Proteobacteria,1S3RF@1236|Gammaproteobacteria,467A7@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG3038 Cytochrome B561 - - - ko:K12262 - - - - ko00000 - - - Ni_hydr_CYTB k141_16708_1 1121938.AUDY01000009_gene2364 3.94e-187 535.0 COG2015@1|root,COG2015@2|Bacteria,1TR7Q@1239|Firmicutes,4HIVI@91061|Bacilli 91061|Bacilli Q Alkyl sulfatase dimerisation sepA - - - - - - - - - - - Alkyl_sulf_C,Alkyl_sulf_dimr,Lactamase_B k141_14369_1 42565.FP66_14215 3.41e-54 180.0 COG0477@1|root,COG2814@2|Bacteria,1MW19@1224|Proteobacteria,1RMSZ@1236|Gammaproteobacteria,1XH6M@135619|Oceanospirillales 135619|Oceanospirillales EGP Major facilitator superfamily - - - ko:K07552 - - - - ko00000,ko02000 2.A.1.2 - - MFS_1 k141_14369_2 42565.FP66_14220 4.5e-37 133.0 COG0226@1|root,COG0226@2|Bacteria,1MUH9@1224|Proteobacteria,1RN9U@1236|Gammaproteobacteria,1XHR0@135619|Oceanospirillales 135619|Oceanospirillales P Phosphate ABC transporter substrate-binding protein - - - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - PBP_like_2 k141_15564_1 218284.CCDN010000001_gene665 5.66e-73 239.0 COG0608@1|root,COG0608@2|Bacteria,1TPXE@1239|Firmicutes,4H9UP@91061|Bacilli,1ZBAT@1386|Bacillus 91061|Bacilli L Single-stranded-DNA-specific exonuclease RecJ recJ - - ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1,ssDNA-exonuc_C k141_6061_1 1453501.JELR01000001_gene2825 4.31e-90 291.0 COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,1RMGD@1236|Gammaproteobacteria,464UU@72275|Alteromonadaceae 1236|Gammaproteobacteria M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein - - - - - - - - - - - - Mur_ligase_C,Mur_ligase_M,PGA_cap k141_17954_1 218284.CCDN010000001_gene1089 3.6e-218 610.0 COG2959@1|root,COG2959@2|Bacteria,1TT9K@1239|Firmicutes,4HBM9@91061|Bacilli,1ZB4M@1386|Bacillus 91061|Bacilli H sporulation protein ypeB - - ko:K06313 - - - - ko00000 - - - PepSY,YPEB k141_31017_1 1042377.AFPJ01000011_gene427 8.31e-74 232.0 COG2370@1|root,COG2370@2|Bacteria,1MV6Z@1224|Proteobacteria,1RRHA@1236|Gammaproteobacteria,468HI@72275|Alteromonadaceae 1236|Gammaproteobacteria O HupE / UreJ protein - - - - - - - - - - - - HupE_UreJ_2 k141_21521_1 1453498.LG45_16335 4.9e-08 52.4 COG1917@1|root,COG1917@2|Bacteria,4NQ6V@976|Bacteroidetes,1I95T@117743|Flavobacteriia,2NWH1@237|Flavobacterium 976|Bacteroidetes S Cupin 2, conserved barrel domain protein - - - - - - - - - - - - - k141_21521_2 937777.Deipe_0135 1.87e-31 124.0 COG0346@1|root,COG0400@1|root,COG0346@2|Bacteria,COG0400@2|Bacteria,1WICF@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus E glyoxalase bleomycin resistance protein dioxygenase - - - ko:K15975 - - - - ko00000 - - - Abhydrolase_2,Glyoxalase k141_27399_1 1117379.BABA_04609 5.78e-63 207.0 COG0151@1|root,COG0151@2|Bacteria,1UR8C@1239|Firmicutes,4IS9W@91061|Bacilli,1ZF4M@1386|Bacillus 91061|Bacilli F Biotin carboxylase - - - - - - - - - - - - ATP-grasp_4 k141_27399_2 714961.BFZC1_12523 3.13e-117 363.0 COG0189@1|root,COG0770@1|root,COG0189@2|Bacteria,COG0770@2|Bacteria,1TRXK@1239|Firmicutes,4HBN0@91061|Bacilli,3IVS0@400634|Lysinibacillus 91061|Bacilli HJM COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase) - - 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 - R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - ATPgrasp_YheCD,Mur_ligase_C,Mur_ligase_M k141_27399_3 642492.Clole_1211 8.08e-84 259.0 COG0189@1|root,COG0189@2|Bacteria,1TRXK@1239|Firmicutes,24KQ6@186801|Clostridia 186801|Clostridia HJ YheC/D like ATP-grasp - - - - - - - - - - - - ATPgrasp_YheCD k141_3670_1 378806.STAUR_1160 2.36e-29 112.0 COG0625@1|root,COG0625@2|Bacteria,1REDI@1224|Proteobacteria 1224|Proteobacteria O Belongs to the GST superfamily gstA1 - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C,GST_C_2,GST_N,GST_N_3 k141_3670_2 82654.Pse7367_2104 5.27e-10 57.8 COG0251@1|root,COG0251@2|Bacteria 2|Bacteria J oxidation-reduction process - - 3.5.99.10 ko:K09022 - - R11098,R11099 RC03275,RC03354 ko00000,ko01000 - - - Ribonuc_L-PSP k141_14370_1 42565.FP66_10705 3.11e-48 154.0 2E2KE@1|root,32XPQ@2|Bacteria,1N3CH@1224|Proteobacteria,1S951@1236|Gammaproteobacteria,1XKS5@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_23839_1 218284.CCDN010000002_gene2252 5.24e-111 334.0 COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,4HBUS@91061|Bacilli,1ZB01@1386|Bacillus 91061|Bacilli EH Belongs to the TPP enzyme family ydaP - 1.2.3.3 ko:K00158 ko00620,ko01100,map00620,map01100 - R00207 RC02745 ko00000,ko00001,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N k141_26261_1 1294265.JCM21738_3241 6.4e-180 517.0 COG3887@1|root,COG3887@2|Bacteria,1TPGP@1239|Firmicutes,4HBVH@91061|Bacilli,1ZCB0@1386|Bacillus 91061|Bacilli T signaling protein consisting of a modified GGDEF domain and a DHH domain yybT - - - - - - - - - - - DHH,DHHA1 k141_26261_2 1294265.JCM21738_3240 2.05e-46 158.0 COG4241@1|root,COG4241@2|Bacteria,1UZYE@1239|Firmicutes,4HAFH@91061|Bacilli,1ZC1B@1386|Bacillus 91061|Bacilli S membrane yybS - - - - - - - - - - - DUF2232 k141_28646_1 1279017.AQYJ01000028_gene2449 8.49e-52 170.0 COG0235@1|root,COG0235@2|Bacteria,1MWP9@1224|Proteobacteria,1RQNI@1236|Gammaproteobacteria,4643V@72275|Alteromonadaceae 1236|Gammaproteobacteria G Class II aldolase - - - - - - - - - - - - Aldolase_II k141_28646_2 626887.J057_12851 4.94e-33 119.0 COG4341@1|root,COG4341@2|Bacteria,1QHQD@1224|Proteobacteria,1S2ZI@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phosphohydrolase - - - - - - - - - - - - HD k141_13199_1 796606.BMMGA3_12975 7.69e-47 166.0 COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,4HABZ@91061|Bacilli,1ZB5W@1386|Bacillus 91061|Bacilli J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) thrS GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD k141_13199_2 1294265.JCM21738_2771 5.71e-66 207.0 2AZZM@1|root,31S9P@2|Bacteria,1V6WH@1239|Firmicutes,4HMZM@91061|Bacilli,1ZDWA@1386|Bacillus 91061|Bacilli S YtxC-like family ytxC - - - - - - - - - - - YtxC k141_16709_1 218284.CCDN010000006_gene3608 5.95e-103 298.0 COG0691@1|root,COG0691@2|Bacteria,1V3IJ@1239|Firmicutes,4HGZX@91061|Bacilli,1ZFJ0@1386|Bacillus 91061|Bacilli O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene smpB GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0070930,GO:0071704,GO:1901564 - ko:K03664 - - - - ko00000 - - - SmpB k141_20268_1 1279017.AQYJ01000028_gene2405 1.35e-129 389.0 COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,1RMT7@1236|Gammaproteobacteria,466B9@72275|Alteromonadaceae 1236|Gammaproteobacteria S Bacterial protein of unknown function (DUF885) - - - - - - - - - - - - DUF885 k141_20268_2 1453501.JELR01000002_gene528 0.0 1129.0 COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,1RNQD@1236|Gammaproteobacteria,4651D@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) dxs GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008614,GO:0008615,GO:0008654,GO:0008661,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009240,GO:0009987,GO:0016740,GO:0016744,GO:0017144,GO:0018130,GO:0019288,GO:0019438,GO:0019637,GO:0019682,GO:0019752,GO:0019842,GO:0030976,GO:0032787,GO:0034641,GO:0036094,GO:0042180,GO:0042181,GO:0042364,GO:0042723,GO:0042724,GO:0042816,GO:0042819,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:1901135,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663,GO:1901681 2.2.1.7 ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 M00096 R05636 RC00032 ko00000,ko00001,ko00002,ko01000 - - iEcSMS35_1347.EcSMS35_0456,iJN746.PP_0527 DXP_synthase_N,Transket_pyr,Transketolase_C k141_20268_3 1279017.AQYJ01000028_gene2407 7.5e-139 401.0 COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,1RMKY@1236|Gammaproteobacteria,464WM@72275|Alteromonadaceae 1236|Gammaproteobacteria H Belongs to the FPP GGPP synthase family ispA GO:0003674,GO:0003824,GO:0004161,GO:0004337,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016114,GO:0016740,GO:0016765,GO:0019637,GO:0033383,GO:0033384,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0045337,GO:0045338,GO:0071704,GO:0090407,GO:1901576 2.5.1.1,2.5.1.10,2.5.1.29 ko:K00795,ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00366 R01658,R02003,R02061 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 - - iPC815.YPO3176,iSFV_1184.SFV_0386 polyprenyl_synt k141_20268_5 1453501.JELR01000002_gene511 5.86e-205 580.0 COG2133@1|root,COG2133@2|Bacteria,1MVK5@1224|Proteobacteria,1RPE8@1236|Gammaproteobacteria,4665U@72275|Alteromonadaceae 1236|Gammaproteobacteria G COG2133 Glucose sorbosone dehydrogenases - - - - - - - - - - - - GSDH k141_17955_2 1433126.BN938_0922 3.37e-31 122.0 COG1252@1|root,COG1252@2|Bacteria,4NE0H@976|Bacteroidetes,2FNZW@200643|Bacteroidia,22U6M@171550|Rikenellaceae 976|Bacteroidetes C Pyridine nucleotide-disulphide oxidoreductase ndh - 1.6.99.3 ko:K03885 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - Pyr_redox_2 k141_14371_1 218284.CCDN010000001_gene1631 1.24e-63 205.0 COG1366@1|root,COG1366@2|Bacteria,1UNBX@1239|Firmicutes,4HEFW@91061|Bacilli,1ZAYN@1386|Bacillus 91061|Bacilli T Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor) - - - - - - - - - - - - STAS k141_15566_2 859657.RPSI07_mp1074 3.13e-08 56.2 COG0642@1|root,COG2205@2|Bacteria,1N9SU@1224|Proteobacteria,2VI30@28216|Betaproteobacteria,1K545@119060|Burkholderiaceae 28216|Betaproteobacteria T Two-component sensor kinase N-terminal - - 2.7.13.3 ko:K02484 - - - - ko00000,ko01000,ko01001,ko02022 - - - 2CSK_N,HAMP,HATPase_c,HisKA k141_28647_1 218284.CCDN010000004_gene3103 5.47e-36 132.0 COG2610@1|root,COG2610@2|Bacteria,1TQJ6@1239|Firmicutes,4HA01@91061|Bacilli,1ZCGI@1386|Bacillus 91061|Bacilli EG COG2610 H gluconate symporter and related permeases - - - - - - - - - - - - GntP_permease k141_28647_2 218284.CCDN010000004_gene3104 5.65e-80 249.0 COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,4H9SB@91061|Bacilli,1ZBAN@1386|Bacillus 91061|Bacilli S COG1253 Hemolysins and related proteins containing CBS domains yhdP - - - - - - - - - - - CBS,CorC_HlyC,DUF21 k141_31020_1 218284.CCDN010000008_gene4136 1.68e-148 428.0 COG0297@1|root,COG0297@2|Bacteria,1TQ4M@1239|Firmicutes,4HAVA@91061|Bacilli,1ZDBA@1386|Bacillus 91061|Bacilli G Synthesizes alpha-1,4-glucan chains using ADP-glucose glgA GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009011,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 M00565 R02421 RC00005 ko00000,ko00001,ko00002,ko01000,ko01003 - GT5 - Glyco_transf_5,Glycos_transf_1 k141_25029_1 218284.CCDN010000005_gene3448 7.45e-48 169.0 COG1009@1|root,COG2111@1|root,COG1009@2|Bacteria,COG2111@2|Bacteria,1TQW4@1239|Firmicutes,4H9YR@91061|Bacilli,1ZAZ0@1386|Bacillus 91061|Bacilli CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit mrpA - - ko:K05565 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - DUF4040,Proton_antipo_M,Proton_antipo_N k141_4857_1 1279017.AQYJ01000022_gene2648 2.07e-152 443.0 COG0415@1|root,COG0415@2|Bacteria,1MV9Y@1224|Proteobacteria,1RNGJ@1236|Gammaproteobacteria,4651X@72275|Alteromonadaceae 1236|Gammaproteobacteria L Belongs to the DNA photolyase family phrB GO:0003674,GO:0003824,GO:0003904,GO:0003913,GO:0006139,GO:0006259,GO:0006281,GO:0006464,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0018298,GO:0019538,GO:0033554,GO:0034641,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360,GO:1901564 4.1.99.3 ko:K01669 - - - - ko00000,ko01000,ko03400 - - - DNA_photolyase,FAD_binding_7 k141_8448_2 1517681.HW45_22485 6.6e-111 325.0 COG2063@1|root,COG2063@2|Bacteria,1RDEY@1224|Proteobacteria,1S3XK@1236|Gammaproteobacteria,1Y2MU@135623|Vibrionales 135623|Vibrionales N Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation - - - ko:K02393 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FlgH k141_15751_1 218284.CCDN010000001_gene1408 1.99e-107 316.0 COG4086@1|root,COG4086@2|Bacteria,1TR2I@1239|Firmicutes,4HBVZ@91061|Bacilli,1ZD5H@1386|Bacillus 91061|Bacilli S Secreted protein ypuA - - - - - - - - - - - DUF1002 k141_2678_1 1279017.AQYJ01000023_gene3192 4.28e-109 325.0 COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,1RMN5@1236|Gammaproteobacteria,465H9@72275|Alteromonadaceae 1236|Gammaproteobacteria S permeases lptF - - ko:K07091 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko02000 1.B.42.1 - - YjgP_YjgQ k141_2678_2 1279017.AQYJ01000023_gene3193 2.43e-178 504.0 COG0795@1|root,COG0795@2|Bacteria,1MVW3@1224|Proteobacteria,1RM8H@1236|Gammaproteobacteria,465SX@72275|Alteromonadaceae 1236|Gammaproteobacteria S permease lptG - - ko:K11720 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko02000 1.B.42.1 - - YjgP_YjgQ k141_2678_3 1279017.AQYJ01000023_gene3194 1.73e-80 242.0 COG1714@1|root,COG1714@2|Bacteria,1N7R6@1224|Proteobacteria,1SCCT@1236|Gammaproteobacteria,468CD@72275|Alteromonadaceae 1236|Gammaproteobacteria S membrane protein domain - - - - - - - - - - - - RDD k141_2678_5 1279017.AQYJ01000023_gene3293 8.12e-49 175.0 COG3525@1|root,COG3525@2|Bacteria,1MVDE@1224|Proteobacteria,1RMNI@1236|Gammaproteobacteria,465K7@72275|Alteromonadaceae 1236|Gammaproteobacteria G Putative carbohydrate binding domain chb - 3.2.1.52 ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 M00079 R00022,R06004,R11316 RC00049 ko00000,ko00001,ko00002,ko01000,ko03110 - GH20 - CHB_HEX,CHB_HEX_C,Glyco_hydro_20,Glyco_hydro_20b k141_8603_1 218284.CCDN010000002_gene2110 6.07e-176 496.0 COG3185@1|root,COG3185@2|Bacteria,1UZP2@1239|Firmicutes,4HDQI@91061|Bacilli,1ZEQ2@1386|Bacillus 91061|Bacilli E 4-hydroxyphenylpyruvate dioxygenase hppD - 1.13.11.27 ko:K00457 ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100 M00044 R01372,R02521 RC00505,RC00738 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Glyoxalase,Glyoxalase_5 k141_8603_3 218284.CCDN010000002_gene2112 5.39e-125 358.0 COG1853@1|root,COG1853@2|Bacteria,1V52S@1239|Firmicutes,4HGD9@91061|Bacilli,1ZB1C@1386|Bacillus 91061|Bacilli S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family - - - - - - - - - - - - Flavin_Reduct k141_8603_4 218284.CCDN010000002_gene2113 3.55e-99 296.0 COG0179@1|root,COG0179@2|Bacteria,1UY98@1239|Firmicutes,4HC89@91061|Bacilli,1ZCD1@1386|Bacillus 91061|Bacilli Q Fumarylacetoacetate (FAA) hydrolase family - - 3.7.1.2 ko:K16171 ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120 M00044 R01364 RC00326,RC00446 ko00000,ko00001,ko00002,ko01000 - - - FAA_hydrolase k141_26577_1 1078085.HMPREF1210_00116 2.3e-78 238.0 COG0693@1|root,COG0693@2|Bacteria,1V4DK@1239|Firmicutes,4IQYP@91061|Bacilli,26FAA@186818|Planococcaceae 91061|Bacilli S DJ-1/PfpI family - - 3.5.1.124 ko:K03152 - - - - ko00000,ko01000,ko01002 - - - DJ-1_PfpI k141_10957_1 218284.CCDN010000001_gene1851 9.69e-98 300.0 COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1TSSC@1239|Firmicutes,4HA8C@91061|Bacilli,1ZBA6@1386|Bacillus 91061|Bacilli C COG1014 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, gamma subunit korA - 1.2.7.11,1.2.7.3 ko:K00174 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - PFOR_II,POR,POR_N k141_10957_2 935837.JAEK01000005_gene4396 2.63e-88 265.0 COG1013@1|root,COG1013@2|Bacteria,1TQJ2@1239|Firmicutes,4HAA4@91061|Bacilli,1ZCCX@1386|Bacillus 91061|Bacilli C COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit korB - 1.2.7.11,1.2.7.3 ko:K00175 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - PFO_beta_C,TPP_enzyme_C k141_3896_1 1042377.AFPJ01000037_gene2894 1.5e-109 320.0 COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,1RQ4B@1236|Gammaproteobacteria,466FV@72275|Alteromonadaceae 1236|Gammaproteobacteria L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03470 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_HII k141_20413_1 218284.CCDN010000005_gene3182 2.04e-128 369.0 28I6D@1|root,2Z89E@2|Bacteria,1TQNW@1239|Firmicutes,4HCGQ@91061|Bacilli,1ZAQM@1386|Bacillus 91061|Bacilli S EcsC protein family ecsC - - - - - - - - - - - EcsC k141_37061_1 218284.CCDN010000001_gene1116 7.86e-58 181.0 COG4401@1|root,COG4401@2|Bacteria,1VAID@1239|Firmicutes,4HKTN@91061|Bacilli,1ZH0S@1386|Bacillus 91061|Bacilli E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis aroH GO:0003674,GO:0003824,GO:0004106,GO:0006082,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044281,GO:0046417,GO:0071704 5.4.99.5 ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024,M00025 R01715 RC03116 ko00000,ko00001,ko00002,ko01000 - - - CM_1 k141_21696_1 1279017.AQYJ01000022_gene2746 4.17e-200 558.0 COG0042@1|root,COG0042@2|Bacteria,1MUY1@1224|Proteobacteria,1RN28@1236|Gammaproteobacteria,464FI@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs dusA GO:0002943,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016491,GO:0016627,GO:0017150,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055114,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 - ko:K05539 - - - - ko00000,ko01000,ko03016 - - - Dus k141_21696_2 1042377.AFPJ01000052_gene1560 3.54e-163 464.0 COG0176@1|root,COG0176@2|Bacteria,1MWQ8@1224|Proteobacteria,1RMS0@1236|Gammaproteobacteria,465PU@72275|Alteromonadaceae 1236|Gammaproteobacteria G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway tal GO:0003674,GO:0003824,GO:0004801,GO:0016740,GO:0016744 2.2.1.2 ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01827 RC00439,RC00604 ko00000,ko00001,ko00002,ko01000 - - - TAL_FSA k141_21696_3 1042377.AFPJ01000052_gene1561 4.2e-71 218.0 COG4103@1|root,COG4103@2|Bacteria,1N6YZ@1224|Proteobacteria,1SD1K@1236|Gammaproteobacteria,468DI@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - TerB k141_21696_4 1279017.AQYJ01000022_gene2743 5.92e-93 275.0 COG1366@1|root,COG1366@2|Bacteria,1RIIT@1224|Proteobacteria,1S4RH@1236|Gammaproteobacteria,4678J@72275|Alteromonadaceae 1236|Gammaproteobacteria T Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor) - - - - - - - - - - - - STAS k141_28867_1 1196031.ALEG01000049_gene352 2.92e-14 66.2 2DIQB@1|root,303WI@2|Bacteria,1TVCP@1239|Firmicutes,4IJW2@91061|Bacilli,1ZK1N@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_24017_1 1279017.AQYJ01000023_gene3085 3.49e-204 580.0 COG0471@1|root,COG0569@1|root,COG0471@2|Bacteria,COG0569@2|Bacteria,1MU0K@1224|Proteobacteria,1RMI1@1236|Gammaproteobacteria,464A6@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0471 Di- and tricarboxylate transporters - - - - - - - - - - - - CitMHS,TrkA_C k141_34754_1 1033734.CAET01000038_gene139 1.14e-86 265.0 COG0491@1|root,COG0491@2|Bacteria,1V8JE@1239|Firmicutes,4HIYW@91061|Bacilli,1ZEQ1@1386|Bacillus 91061|Bacilli S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B k141_34754_2 1196028.ALEF01000005_gene3356 4.45e-11 62.0 arCOG10603@1|root,32SV6@2|Bacteria,1V1HA@1239|Firmicutes,4HFU1@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - k141_26578_1 1121342.AUCO01000005_gene188 4.28e-65 216.0 COG4656@1|root,COG4656@2|Bacteria,1TPCC@1239|Firmicutes,24805@186801|Clostridia,36F8C@31979|Clostridiaceae 186801|Clostridia C Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily rnfC - - ko:K03615 - - - - ko00000 - - - Complex1_51K,Fer4,Fer4_10,Fer4_7,Fer4_9,RnfC_N,SLBB k141_31222_1 218284.CCDN010000005_gene3184 3.27e-20 88.2 COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,4H9WQ@91061|Bacilli,1ZAR7@1386|Bacillus 91061|Bacilli E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase yhaA - - ko:K01436 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 k141_31222_2 218284.CCDN010000005_gene3185 1.21e-44 150.0 COG0671@1|root,COG0671@2|Bacteria,1VF2U@1239|Firmicutes,4HNXR@91061|Bacilli,1ZDET@1386|Bacillus 91061|Bacilli I Acid phosphatase homologues pgpB1 - 3.6.1.27 ko:K19302 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - PAP2 k141_22897_2 1499685.CCFJ01000006_gene2104 1.53e-180 514.0 COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,4HB0P@91061|Bacilli,1ZQFT@1386|Bacillus 91061|Bacilli L transposase mutator type - - - - - - - - - - - - Transposase_mut k141_380_1 1354303.M917_1397 1.51e-28 114.0 COG3048@1|root,COG3048@2|Bacteria,1MUJS@1224|Proteobacteria,1RNBW@1236|Gammaproteobacteria,3NKT6@468|Moraxellaceae 1236|Gammaproteobacteria E Belongs to the serine threonine dehydratase family. DsdA subfamily dsdA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0008721,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009636,GO:0009987,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016840,GO:0016841,GO:0017144,GO:0019478,GO:0019752,GO:0019842,GO:0030170,GO:0033554,GO:0036088,GO:0036094,GO:0042221,GO:0042737,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046416,GO:0048037,GO:0050662,GO:0050896,GO:0051410,GO:0051716,GO:0070178,GO:0070279,GO:0071704,GO:0097159,GO:0098754,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901698 4.3.1.18 ko:K01753 ko00260,map00260 - R00221 RC02600 ko00000,ko00001,ko01000 - - iECED1_1282.ECED1_2813,iLF82_1304.LF82_0525,iNRG857_1313.NRG857_11890 PALP k141_5009_1 218284.CCDN010000001_gene806 1.63e-197 561.0 COG1368@1|root,COG1368@2|Bacteria,1TRMA@1239|Firmicutes,4H9S0@91061|Bacilli,1ZBBV@1386|Bacillus 91061|Bacilli M Belongs to the LTA synthase family yqgS - 2.7.8.20 ko:K01138,ko:K19005 ko00561,ko01100,map00561,map01100 - R05081,R10849 RC00017 ko00000,ko00001,ko01000 - - - Sulfatase k141_33536_2 1279017.AQYJ01000024_gene921 3.33e-197 551.0 COG2951@1|root,COG2951@2|Bacteria,1MUZ3@1224|Proteobacteria,1RMQ6@1236|Gammaproteobacteria,4659R@72275|Alteromonadaceae 1236|Gammaproteobacteria M Lytic murein transglycosylase mltB - - ko:K08305 - - - - ko00000,ko01000,ko01011 - GH103 - SLT_2 k141_33536_3 1453501.JELR01000002_gene141 9.6e-226 627.0 COG0772@1|root,COG0772@2|Bacteria,1MUK3@1224|Proteobacteria,1RMEJ@1236|Gammaproteobacteria,464B2@72275|Alteromonadaceae 1236|Gammaproteobacteria M Peptidoglycan polymerase that is essential for cell wall elongation mrdB GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008360,GO:0016020,GO:0022603,GO:0022604,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944 - ko:K05837 - - - - ko00000,ko03036 - - - FTSW_RODA_SPOVE k141_21697_1 1305836.AXVE01000011_gene1018 2.02e-110 329.0 COG3459@1|root,COG3459@2|Bacteria,1TQY8@1239|Firmicutes,4HBZV@91061|Bacilli,26GM9@186818|Planococcaceae 91061|Bacilli G Protein of unknown function (DUF3131) - - - - - - - - - - - - DUF3131,Glycoamylase k141_37062_2 218284.CCDN010000005_gene3451 2.89e-21 93.6 COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4HBBB@91061|Bacilli,1ZCKA@1386|Bacillus 91061|Bacilli M Penicillin-binding Protein pbpD - 2.4.1.129,3.4.16.4 ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase k141_10958_1 1279017.AQYJ01000028_gene2366 8.4e-96 284.0 COG2109@1|root,COG2109@2|Bacteria,1MUN6@1224|Proteobacteria,1RMH9@1236|Gammaproteobacteria,4642W@72275|Alteromonadaceae 1236|Gammaproteobacteria H Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids btuR GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008817,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019250,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.17 ko:K19221 ko00860,ko01100,map00860,map01100 M00122 R01492,R05220,R07268 RC00533 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b1270,iB21_1397.B21_01256,iBWG_1329.BWG_1099,iECABU_c1320.ECABU_c15500,iECBD_1354.ECBD_2352,iECB_1328.ECB_01246,iECDH10B_1368.ECDH10B_1385,iECDH1ME8569_1439.ECDH1ME8569_1209,iECD_1391.ECD_01246,iECIAI1_1343.ECIAI1_1288,iECO111_1330.ECO111_1649,iECO26_1355.ECO26_1834,iETEC_1333.ETEC_1372,iEcDH1_1363.EcDH1_2379,iEcHS_1320.EcHS_A1379,iJO1366.b1270,iJR904.b1270,iLF82_1304.LF82_0253,iNRG857_1313.NRG857_06515,iUMNK88_1353.UMNK88_1599,iY75_1357.Y75_RS06640,iYL1228.KPN_01266,ic_1306.c1735 Co_AT_N,CobA_CobO_BtuR k141_18173_1 1541065.JRFE01000057_gene6278 2.06e-85 267.0 COG0530@1|root,COG0530@2|Bacteria,1G7C1@1117|Cyanobacteria 1117|Cyanobacteria P Sodium/calcium exchanger protein - - - - - - - - - - - - Na_Ca_ex k141_19283_1 420246.GTNG_2800 5.02e-56 179.0 COG0454@1|root,COG0456@2|Bacteria,1VABX@1239|Firmicutes,4IS9Z@91061|Bacilli,1WGCR@129337|Geobacillus 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_10 k141_19283_2 1305836.AXVE01000015_gene3047 5.34e-36 125.0 2E9S0@1|root,333Y5@2|Bacteria,1VFEQ@1239|Firmicutes,4HNHH@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - k141_9766_2 796606.BMMGA3_05970 7.55e-38 127.0 COG0236@1|root,COG0236@2|Bacteria,1VEE3@1239|Firmicutes,4HNQ0@91061|Bacilli,1ZHY7@1386|Bacillus 91061|Bacilli IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis acpP GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - ko:K02078 - - - - ko00000,ko00001 - - - PP-binding k141_9766_3 1262915.BN574_00399 2.83e-09 56.6 COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,4H2JC@909932|Negativicutes 909932|Negativicutes IQ reductase fabG - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 k141_3921_1 743722.Sph21_3087 4.08e-29 121.0 COG1629@1|root,COG4771@2|Bacteria,4NGAK@976|Bacteroidetes,1INVJ@117747|Sphingobacteriia 976|Bacteroidetes P Carboxypeptidase regulatory-like domain - - - - - - - - - - - - CarboxypepD_reg k141_35909_1 1267533.KB906736_gene1102 5.46e-80 253.0 COG0538@1|root,COG0538@2|Bacteria,3Y2WW@57723|Acidobacteria,2JHTU@204432|Acidobacteriia 204432|Acidobacteriia C TIGRFAM isocitrate dehydrogenase, NADP-dependent - - 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh k141_388_1 1117379.BABA_18417 7.48e-109 331.0 COG1657@1|root,COG1657@2|Bacteria,1TRRG@1239|Firmicutes,4HA2Q@91061|Bacilli,1ZFH9@1386|Bacillus 91061|Bacilli I Squalene-hopene cyclase C-terminal domain sqhC - 4.2.1.137 ko:K18115 - - - - ko00000,ko01000 - - - SQHop_cyclase_C,SQHop_cyclase_N k141_15767_1 1294265.JCM21738_1157 2.94e-37 127.0 COG0626@1|root,COG0626@2|Bacteria,1TPC7@1239|Firmicutes,4HAFQ@91061|Bacilli,1ZAR9@1386|Bacillus 91061|Bacilli E cystathionine mccB GO:0000096,GO:0000098,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008284,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019752,GO:0042127,GO:0043418,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0048518,GO:0048522,GO:0050667,GO:0050789,GO:0050794,GO:0065007,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 4.4.1.1,4.4.1.2,4.4.1.8 ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017,M00609 R00782,R01001,R01283,R01286,R02408,R04941 RC00056,RC00069,RC00348,RC00382,RC00487,RC00488,RC00710,RC01245,RC02303,RC02814 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU27250 Cys_Met_Meta_PP k141_15767_2 1294265.JCM21738_1158 4.84e-95 283.0 COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,4HAMU@91061|Bacilli,1ZD93@1386|Bacillus 91061|Bacilli E Cysteine synthase mccA GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004122,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008284,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016835,GO:0016836,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042127,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0065007,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.134,2.5.1.47 ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021,M00609 R00897,R03601,R04859,R10305 RC00020,RC00069,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS02385 PALP k141_21714_2 42565.FP66_07235 8.52e-12 67.4 COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,1RN3V@1236|Gammaproteobacteria,1XHDN@135619|Oceanospirillales 135619|Oceanospirillales FP Belongs to the GppA Ppx family ppx - 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 - R03409 RC00002 ko00000,ko00001,ko01000 - - - HD,Ppx-GppA k141_29942_1 218284.CCDN010000007_gene3865 1.85e-20 89.4 COG2610@1|root,COG2610@2|Bacteria,1TQJ6@1239|Firmicutes,4HA01@91061|Bacilli,1ZCGI@1386|Bacillus 91061|Bacilli EG COG2610 H gluconate symporter and related permeases - - - - - - - - - - - - GntP_permease k141_29942_2 218284.CCDN010000007_gene3866 2.12e-74 229.0 COG1028@1|root,COG1028@2|Bacteria,1TP3G@1239|Firmicutes,4HACT@91061|Bacilli,1ZDEW@1386|Bacillus 91061|Bacilli IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate - - 1.1.1.30 ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 M00088 R01361 RC00117 ko00000,ko00001,ko00002,ko01000 - - - adh_short_C2 k141_13419_2 1305836.AXVE01000012_gene87 3.25e-83 255.0 COG1073@1|root,COG1073@2|Bacteria,1TTC0@1239|Firmicutes,4HHKI@91061|Bacilli,26FN9@186818|Planococcaceae 91061|Bacilli K Dienelactone hydrolase family - - - ko:K06889 - - - - ko00000 - - - Hydrolase_4,Peptidase_S9 k141_7434_1 985665.HPL003_11005 2.69e-28 118.0 COG0553@1|root,COG4715@1|root,COG0553@2|Bacteria,COG4715@2|Bacteria,1TPFZ@1239|Firmicutes,4HAIF@91061|Bacilli,26R9Z@186822|Paenibacillaceae 91061|Bacilli L Helicase SNF snf - - - - - - - - - - - Helicase_C,SNF2_N,SNF2_assoc,SWIM k141_22921_1 1294265.JCM21738_328 1.05e-44 147.0 COG0835@1|root,COG0835@2|Bacteria,1V4HH@1239|Firmicutes,4HHB5@91061|Bacilli,1ZGZE@1386|Bacillus 91061|Bacilli NT COG0835 Chemotaxis signal transduction protein cheW GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006935,GO:0008150,GO:0009453,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0042333,GO:0044424,GO:0044444,GO:0044464,GO:0050896 - ko:K03408 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - CheW k141_22921_2 1294265.JCM21738_327 4.83e-110 335.0 COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1TPMS@1239|Firmicutes,4HAQD@91061|Bacilli,1ZATW@1386|Bacillus 91061|Bacilli NT COG0643 Chemotaxis protein histidine kinase and related kinases cheA - 2.7.13.3 ko:K03407 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt,P2 k141_5036_1 663610.JQKO01000010_gene2275 2.6e-16 86.3 COG0457@1|root,COG0457@2|Bacteria,1MX2U@1224|Proteobacteria,2TVI2@28211|Alphaproteobacteria,3NA3Z@45404|Beijerinckiaceae 28211|Alphaproteobacteria C Doubled CXXCH motif (Paired_CXXCH_1) - - - - - - - - - - - - Cytochrome_C554,HEAT_2,Paired_CXXCH_1,TPR_14,TPR_16,TPR_19,TPR_2,TPR_8 k141_27562_1 218284.CCDN010000001_gene610 5.04e-22 95.5 COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,4HBJM@91061|Bacilli,1ZAWN@1386|Bacillus 91061|Bacilli H Belongs to the folylpolyglutamate synthase family folC GO:0003674,GO:0003824,GO:0004326,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006761,GO:0006807,GO:0008150,GO:0008152,GO:0008841,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046452,GO:0046483,GO:0046900,GO:0046901,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 - - - Mur_ligase_C,Mur_ligase_M k141_389_1 113355.CM001775_gene898 1.95e-05 53.5 COG0438@1|root,COG0438@2|Bacteria,1G4YC@1117|Cyanobacteria 1117|Cyanobacteria M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_trans_1_4,Glyco_transf_4 k141_10970_1 1116375.VEJY3_21726 3.7e-116 337.0 2DBXS@1|root,2ZBR1@2|Bacteria,1RBUD@1224|Proteobacteria,1S1ZK@1236|Gammaproteobacteria,1Y1GH@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_10970_2 349521.HCH_01850 3.38e-113 352.0 COG3868@1|root,COG3868@2|Bacteria,1PIK8@1224|Proteobacteria,1RZGT@1236|Gammaproteobacteria,1XJB8@135619|Oceanospirillales 135619|Oceanospirillales S Glycoside-hydrolase family GH114 - - - - - - - - - - - - Glyco_hydro_114 k141_10970_3 1216007.AOPM01000120_gene823 2.58e-178 513.0 COG4267@1|root,COG4267@2|Bacteria,1MUQN@1224|Proteobacteria,1RP96@1236|Gammaproteobacteria,2Q49V@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria S Putative exopolysaccharide Exporter (EPS-E) pelG - - ko:K21012 ko02025,map02025 - - - ko00000,ko00001 - - - PelG k141_10970_4 754436.JCM19237_5922 3.09e-260 726.0 COG0438@1|root,COG0438@2|Bacteria,1MVEG@1224|Proteobacteria,1RY62@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Glycosyl Transferase pelF - - ko:K20921,ko:K21011 ko02025,ko05111,map02025,map05111 - - - ko00000,ko00001,ko01003 - GT4 - DUF3492,Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1 k141_10970_5 754436.JCM19237_5921 2.8e-36 134.0 COG1413@1|root,COG1413@2|Bacteria 2|Bacteria C deoxyhypusine monooxygenase activity - - - - - - - - - - - - HEAT,HEAT_2 k141_10970_6 754436.JCM19237_5918 2.04e-157 459.0 COG2203@1|root,COG2203@2|Bacteria,1PB4M@1224|Proteobacteria,1S5S4@1236|Gammaproteobacteria 1236|Gammaproteobacteria T PelD GGDEF domain pelD - - ko:K21009 ko02025,map02025 - - - ko00000,ko00001 - - - GAF_3,PelD_GGDEF k141_10970_7 754436.JCM19237_5917 3.18e-54 176.0 COG5616@1|root,COG5616@2|Bacteria,1N092@1224|Proteobacteria,1SC9K@1236|Gammaproteobacteria 1236|Gammaproteobacteria S cAMP biosynthetic process - - - ko:K21008 ko02025,map02025 - - - ko00000,ko00001 - - - - k141_3922_1 218284.CCDN010000002_gene2096 4.12e-146 419.0 COG2070@1|root,COG2070@2|Bacteria,1TPC3@1239|Firmicutes,4H9T0@91061|Bacilli,1ZBRG@1386|Bacillus 91061|Bacilli S COG2070 Dioxygenases related to 2-nitropropane dioxygenase fabK - 1.3.1.9 ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00083 R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765 RC00052,RC00076 ko00000,ko00001,ko00002,ko01000,ko01004 - - - NMO k141_2701_1 1453501.JELR01000002_gene712 8.17e-105 309.0 COG2207@1|root,COG2207@2|Bacteria,1Q4N1@1224|Proteobacteria,1S07G@1236|Gammaproteobacteria,46CNU@72275|Alteromonadaceae 1236|Gammaproteobacteria K AraC-type transcriptional regulator N-terminus - - - - - - - - - - - - AraC_N,HTH_18,HTH_AraC k141_16979_1 1294265.JCM21738_4013 1.25e-121 361.0 COG4365@1|root,COG4365@2|Bacteria,1TQ2P@1239|Firmicutes,4HA2Z@91061|Bacilli,1ZBMV@1386|Bacillus 91061|Bacilli S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH bshC - - ko:K22136 - - - - ko00000 - - - BshC k141_26616_1 218284.CCDN010000001_gene807 4.85e-117 345.0 COG2866@1|root,COG2866@2|Bacteria,1TP3K@1239|Firmicutes,4HAHN@91061|Bacilli,1ZD1J@1386|Bacillus 91061|Bacilli E Gamma-D-glutamyl-L-diamino acid endopeptidase yqgT GO:0003674,GO:0003824,GO:0004180,GO:0004181,GO:0005575,GO:0005576,GO:0005615,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0044421,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.19.11 ko:K01308 - - - - ko00000,ko01000,ko01002 - - - LysM,Peptidase_M14 k141_25273_1 218284.CCDN010000012_gene4434 1.41e-278 767.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,4H9V3@91061|Bacilli,1ZC91@1386|Bacillus 91061|Bacilli F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth guaB GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 - - - CBS,IMPDH k141_37080_1 1430331.EP10_01475 1.27e-93 288.0 COG3666@1|root,COG3666@2|Bacteria,1TQQ9@1239|Firmicutes,4H9KK@91061|Bacilli,1WGI6@129337|Geobacillus 91061|Bacilli L PFAM Transposase, IS4-like - - - - - - - - - - - - DDE_Tnp_1,DDE_Tnp_1_6,DUF772 k141_1433_1 1294265.JCM21738_67 1.26e-60 196.0 COG4955@1|root,COG4955@2|Bacteria,1TQU9@1239|Firmicutes,4HFUR@91061|Bacilli,1ZDGR@1386|Bacillus 91061|Bacilli S protein conserved in bacteria ypbB - 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 - - - HTH_40,RQC k141_1433_2 1294265.JCM21738_68 4.9e-151 426.0 COG0514@1|root,COG0514@2|Bacteria,1TPN5@1239|Firmicutes,4H9QP@91061|Bacilli,1ZB1X@1386|Bacillus 91061|Bacilli L DNA helicase recQ GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009378,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.6.4.12 ko:K03654 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecQ_Zn_bind k141_22923_1 398720.MED217_14945 1.09e-58 194.0 COG4409@1|root,COG4409@2|Bacteria 2|Bacteria G exo-alpha-(2->6)-sialidase activity nanH - 3.2.1.18 ko:K01186 ko00511,ko00600,ko04142,map00511,map00600,map04142 - R04018 RC00028,RC00077 ko00000,ko00001,ko01000,ko02042 - GH33 - BNR_2,CW_binding_1,F5_F8_type_C,NPCBM_assoc k141_6360_1 1121438.JNJA01000004_gene577 2.16e-57 192.0 COG1566@1|root,COG1566@2|Bacteria,1MWG0@1224|Proteobacteria,42NAT@68525|delta/epsilon subdivisions,2WPPB@28221|Deltaproteobacteria,2MBTW@213115|Desulfovibrionales 28221|Deltaproteobacteria V Biotin-lipoyl like - - - - - - - - - - - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 k141_6360_2 1279017.AQYJ01000029_gene3816 2.11e-69 227.0 COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,1RN5K@1236|Gammaproteobacteria,466GP@72275|Alteromonadaceae 1236|Gammaproteobacteria MU Outer membrane efflux protein lprN - - - - - - - - - - - OEP k141_32308_1 240302.BN982_03637 6.59e-63 214.0 COG2866@1|root,COG2866@2|Bacteria,1TSF6@1239|Firmicutes,4HDT5@91061|Bacilli 91061|Bacilli E Carboxypeptidase - - - - - - - - - - - - Peptidase_M14 k141_22924_2 218284.CCDN010000003_gene2977 3.89e-22 93.6 28HCB@1|root,2Z7P7@2|Bacteria,1TNZK@1239|Firmicutes,4HBET@91061|Bacilli,1ZCTC@1386|Bacillus 91061|Bacilli S peptidase yabG GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0031160,GO:0043591,GO:0043593,GO:0044426,GO:0044462,GO:0044464,GO:0071944 - ko:K06436 - - - - ko00000 - - - Peptidase_U57 k141_35911_1 1042377.AFPJ01000043_gene839 8.79e-82 249.0 COG2269@1|root,COG2269@2|Bacteria,1MU97@1224|Proteobacteria,1RMR9@1236|Gammaproteobacteria,4645R@72275|Alteromonadaceae 1236|Gammaproteobacteria J COG2269 Truncated, possibly inactive, lysyl-tRNA synthetase (class II) epmA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006430,GO:0006464,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016746,GO:0016755,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052868,GO:0071704,GO:0071915,GO:0072580,GO:0072581,GO:0090304,GO:0140096,GO:1901360,GO:1901564,GO:1901566,GO:1901576 - ko:K04568 - - - - ko00000,ko01000,ko03012 - - - tRNA-synt_2 k141_10971_1 1499680.CCFE01000018_gene1553 5.02e-57 184.0 COG1806@1|root,COG1806@2|Bacteria,1TPG0@1239|Firmicutes,4HB0Q@91061|Bacilli,1ZBIT@1386|Bacillus 91061|Bacilli S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation yqfL - 2.7.11.33,2.7.4.28 ko:K09773 - - - - ko00000,ko01000 - - - Kinase-PPPase k141_10971_2 1294265.JCM21738_3322 1.01e-73 221.0 COG1671@1|root,COG1671@2|Bacteria,1V9Z0@1239|Firmicutes,4HM1G@91061|Bacilli,1ZFK7@1386|Bacillus 91061|Bacilli S Belongs to the UPF0178 family yqxD - - ko:K09768 - - - - ko00000 - - - DUF188 k141_24048_1 1236973.JCM9157_780 8.66e-151 452.0 COG3540@1|root,COG3540@2|Bacteria,1VS25@1239|Firmicutes,4HUTD@91061|Bacilli,1ZD0T@1386|Bacillus 91061|Bacilli P Alkaline phosphatase - - - - - - - - - - - - PhoD k141_14528_1 1042377.AFPJ01000048_gene2684 5.38e-156 473.0 COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,1RSKR@1236|Gammaproteobacteria,46BA9@72275|Alteromonadaceae 1236|Gammaproteobacteria KLT Protein tyrosine kinase - - 2.7.11.1 ko:K08884,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - Pkinase,TPR_16,TPR_19,TPR_2,TPR_8 k141_14528_2 1279017.AQYJ01000028_gene2417 5.28e-99 315.0 COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,1RSKR@1236|Gammaproteobacteria,46CIZ@72275|Alteromonadaceae 1236|Gammaproteobacteria KLT Lipopolysaccharide kinase (Kdo/WaaP) family - - 2.7.11.1 ko:K08884,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - Pkinase,TPR_16,TPR_19,TPR_2,TPR_8 k141_28886_1 218284.CCDN010000012_gene4445 2.75e-152 441.0 COG2812@1|root,COG2812@2|Bacteria,1TPS9@1239|Firmicutes,4HAUE@91061|Bacilli,1ZB2M@1386|Bacillus 91061|Bacilli L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity dnaX GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNA_pol3_gamma3 k141_15770_1 1122915.AUGY01000083_gene4492 1.55e-31 116.0 2CDA7@1|root,333AV@2|Bacteria,1VHFF@1239|Firmicutes,4HRPJ@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - k141_22925_1 1403313.AXBR01000005_gene1801 3.77e-56 182.0 COG0515@1|root,COG0515@2|Bacteria,1VBSJ@1239|Firmicutes,4HKRP@91061|Bacilli,1ZHE2@1386|Bacillus 91061|Bacilli KLT COG0515 Serine threonine protein kinase - - - - - - - - - - - - RIO1 k141_16980_1 1123237.Salmuc_00616 4.53e-63 202.0 COG1896@1|root,COG1896@2|Bacteria,1MXEZ@1224|Proteobacteria,2U0WW@28211|Alphaproteobacteria 28211|Alphaproteobacteria S hydrolases of HD superfamily - - - ko:K07023 - - - - ko00000 - - - HD_3 k141_10972_1 1384057.CD33_03440 9e-74 242.0 COG2409@1|root,COG2409@2|Bacteria,1TQ7C@1239|Firmicutes,4H9XX@91061|Bacilli,3IW97@400634|Lysinibacillus 91061|Bacilli S MMPL family - - - ko:K06994 - - - - ko00000 - - - MMPL k141_18198_1 218284.CCDN010000001_gene1252 1.07e-108 322.0 COG1228@1|root,COG1228@2|Bacteria,1TPNQ@1239|Firmicutes,4H9VP@91061|Bacilli,1ZBB1@1386|Bacillus 91061|Bacilli Q COG1228 Imidazolonepropionase and related amidohydrolases hutI - - - - - - - - - - - Amidohydro_1,Amidohydro_3 k141_18473_1 218284.CCDN010000001_gene1880 4.17e-261 719.0 COG0612@1|root,COG0612@2|Bacteria,1TP5I@1239|Firmicutes,4HBBF@91061|Bacilli,1ZDJE@1386|Bacillus 91061|Bacilli S Belongs to the peptidase M16 family mlpA - - - - - - - - - - - Peptidase_M16,Peptidase_M16_C k141_17140_1 1294265.JCM21738_4434 3.74e-100 302.0 COG0654@1|root,COG0654@2|Bacteria,1VS5N@1239|Firmicutes,4HTWN@91061|Bacilli,1ZEQD@1386|Bacillus 91061|Bacilli CH COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - - - - - - - - - - FAD_binding_3 k141_10166_1 1453501.JELR01000002_gene1222 3.99e-39 134.0 COG1495@1|root,COG1495@2|Bacteria,1RKPG@1224|Proteobacteria,1SC4J@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Disulfide bond formation protein DsbB lidJ - - - - - - - - - - - DsbB k141_10166_2 1453501.JELR01000002_gene1220 2.47e-29 110.0 COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,1RP3J@1236|Gammaproteobacteria,464SQ@72275|Alteromonadaceae 1236|Gammaproteobacteria L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates fpg GO:0000702,GO:0000703,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003824,GO:0003906,GO:0004518,GO:0004519,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008270,GO:0008534,GO:0009987,GO:0016787,GO:0016788,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.2.2.23,4.2.99.18 ko:K10563 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Fapy_DNA_glyco,H2TH,zf-FPG_IleRS k141_13786_1 935836.JAEL01000079_gene124 8.47e-95 298.0 COG1009@1|root,COG2111@1|root,COG1009@2|Bacteria,COG2111@2|Bacteria,1TQW4@1239|Firmicutes,4H9YR@91061|Bacilli,1ZAZ0@1386|Bacillus 91061|Bacilli CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit mrpA - - ko:K05565 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - DUF4040,Proton_antipo_M,Proton_antipo_N k141_5379_1 1042377.AFPJ01000023_gene681 4.09e-49 164.0 COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,1RM8G@1236|Gammaproteobacteria,4642K@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives folP GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042221,GO:0042364,GO:0042398,GO:0042493,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046655,GO:0046656,GO:0050896,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.15 ko:K00796 ko00790,ko01100,map00790,map01100 M00126,M00841 R03066,R03067 RC00121,RC00842 ko00000,ko00001,ko00002,ko01000 - - iECO103_1326.ECO103_3924,iPC815.YPO3501 Pterin_bind k141_26929_1 1294265.JCM21738_2564 1.12e-110 325.0 COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,4HA4E@91061|Bacilli,1ZB72@1386|Bacillus 91061|Bacilli P Belongs to the ABC transporter superfamily - - - ko:K02031 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - ABC_tran,oligo_HPY k141_18474_1 985255.APHJ01000017_gene2168 7.32e-40 149.0 COG1409@1|root,COG1409@2|Bacteria,4P3GR@976|Bacteroidetes 976|Bacteroidetes S Calcineurin-like phosphoesterase - - - - - - - - - - - - Metallophos k141_31364_1 1279017.AQYJ01000028_gene2153 3.52e-40 138.0 2EG5Q@1|root,339XK@2|Bacteria,1NGQ6@1224|Proteobacteria,1SHCX@1236|Gammaproteobacteria,46923@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF4168) - - - - - - - - - - - - DUF4168 k141_6525_1 1280001.BAOA01000040_gene2475 5.83e-46 152.0 COG3152@1|root,COG3152@2|Bacteria,1MZJ4@1224|Proteobacteria,1SA1N@1236|Gammaproteobacteria,1XY7E@135623|Vibrionales 135623|Vibrionales S membrane - - - - - - - - - - - - DUF805 k141_10167_1 42565.FP66_14555 1.16e-147 419.0 COG0421@1|root,COG0421@2|Bacteria,1MVV5@1224|Proteobacteria,1RMUT@1236|Gammaproteobacteria,1XHS5@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine speE - 2.5.1.16 ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 M00034,M00133 R01920,R02869,R08359 RC00021,RC00053 ko00000,ko00001,ko00002,ko01000 - - - Spermine_synt_N,Spermine_synth k141_36089_1 218284.CCDN010000002_gene2653 5.58e-47 155.0 COG3708@1|root,COG3708@2|Bacteria,1VB3W@1239|Firmicutes,4HKQB@91061|Bacilli,1ZG5P@1386|Bacillus 91061|Bacilli K Integron-associated effector binding protein - - - - - - - - - - - - Cass2,GyrI-like k141_25618_1 1279017.AQYJ01000029_gene3708 7.3e-244 682.0 COG0155@1|root,COG0155@2|Bacteria,1MVVB@1224|Proteobacteria,1RMFH@1236|Gammaproteobacteria,465NM@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG0155 Sulfite reductase, beta subunit (hemoprotein) cysI - 1.8.1.2 ko:K00381 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00176 R00858 RC00065 ko00000,ko00001,ko00002,ko01000 - - - NIR_SIR,NIR_SIR_ferr k141_24267_2 1279017.AQYJ01000025_gene689 4.67e-198 553.0 COG0500@1|root,COG0500@2|Bacteria,1MVSK@1224|Proteobacteria,1RMQY@1236|Gammaproteobacteria,46D31@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Catalyzes carboxymethyl transfer from carboxy-S- adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs cmoB GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016740,GO:0016741,GO:0016765,GO:0022607,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - ko:K15257 - - - - ko00000,ko01000,ko03016 - - - Methyltransf_9 k141_24267_3 1279017.AQYJ01000025_gene690 1.21e-280 773.0 COG1760@1|root,COG1760@2|Bacteria,1MUZN@1224|Proteobacteria,1RMJZ@1236|Gammaproteobacteria,46637@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG1760 L-serine deaminase sdaA - 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 - R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 - - - SDH_alpha,SDH_beta k141_24267_4 1453501.JELR01000001_gene2152 1.42e-124 362.0 COG0742@1|root,COG0742@2|Bacteria,1MX8Z@1224|Proteobacteria,1RMIB@1236|Gammaproteobacteria,466ZU@72275|Alteromonadaceae 1236|Gammaproteobacteria J Specifically methylates the guanosine in position 1516 of 16S rRNA rsmJ GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036308,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.242 ko:K15984 - - - - ko00000,ko01000,ko03009 - - - SAM_MT k141_24267_5 1042377.AFPJ01000009_gene260 2.01e-42 142.0 2DQ16@1|root,334AZ@2|Bacteria,1N8CC@1224|Proteobacteria,1SCV9@1236|Gammaproteobacteria,46C0B@72275|Alteromonadaceae 1236|Gammaproteobacteria S SpoIIAA-like - - - - - - - - - - - - SpoIIAA-like k141_24267_6 1042377.AFPJ01000009_gene261 8.37e-08 56.6 2EG2H@1|root,339UG@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k141_14731_1 56110.Oscil6304_1385 7.37e-11 62.8 COG2252@1|root,COG2252@2|Bacteria,1G1Y3@1117|Cyanobacteria,1H89W@1150|Oscillatoriales 1117|Cyanobacteria S Permease family - - - ko:K06901 - - - - ko00000,ko02000 2.A.1.40 - - Xan_ur_permease k141_14731_2 1232410.KI421428_gene1139 3.73e-50 162.0 COG3439@1|root,COG3439@2|Bacteria,1RH9Z@1224|Proteobacteria,42VVC@68525|delta/epsilon subdivisions,2WRH9@28221|Deltaproteobacteria,43V7D@69541|Desulfuromonadales 28221|Deltaproteobacteria S Domain of unknown function DUF302 - - - - - - - - - - - - DUF302 k141_26930_1 290400.Jann_3673 2.77e-26 107.0 2DVSI@1|root,33WZN@2|Bacteria,1NK4P@1224|Proteobacteria,2UW3G@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_12615_1 1279017.AQYJ01000025_gene761 1.51e-120 363.0 COG2304@1|root,COG2304@2|Bacteria,1MW51@1224|Proteobacteria,1RMD3@1236|Gammaproteobacteria,464YJ@72275|Alteromonadaceae 1236|Gammaproteobacteria K protein containing a von Willebrand factor type A (vWA) domain - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - TPR_1,TPR_2,VWA_2 k141_12615_2 1453501.JELR01000001_gene2501 2.08e-25 103.0 COG2304@1|root,COG2304@2|Bacteria,1MXQ7@1224|Proteobacteria,1RMDX@1236|Gammaproteobacteria,464NT@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein containing a von Willebrand factor type A (vWA) domain - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - VWA k141_30129_1 1196031.ALEG01000039_gene1703 2.02e-70 236.0 COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,4HA8S@91061|Bacilli,1ZBWA@1386|Bacillus 91061|Bacilli J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,IF-2,IF2_N k141_19595_1 218284.CCDN010000004_gene3068 7.01e-199 560.0 COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,4H9SZ@91061|Bacilli,1ZAX7@1386|Bacillus 91061|Bacilli E Sodium alanine symporter alsT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03310 - - - - ko00000 2.A.25 - - Na_Ala_symp k141_32506_1 1453501.JELR01000001_gene2482 1.25e-57 179.0 2E600@1|root,330PC@2|Bacteria,1N9V9@1224|Proteobacteria,1SD3Y@1236|Gammaproteobacteria,468XD@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_2867_2 1122201.AUAZ01000010_gene2566 1.32e-07 51.2 COG2071@1|root,COG2071@2|Bacteria,1NV5K@1224|Proteobacteria,1T05H@1236|Gammaproteobacteria,4678V@72275|Alteromonadaceae 1236|Gammaproteobacteria S glutamine amidotransferases - - - ko:K07010 - - - - ko00000,ko01002 - - - Peptidase_C26 k141_21925_1 1236541.BALL01000026_gene3027 2.2e-144 430.0 2EXJW@1|root,33QVY@2|Bacteria,1QSMJ@1224|Proteobacteria,1SK5H@1236|Gammaproteobacteria,2QA2U@267890|Shewanellaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_25619_1 218284.CCDN010000007_gene3826 2.75e-107 328.0 COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HA52@91061|Bacilli,1ZCQI@1386|Bacillus 91061|Bacilli T Histidine kinase vicK - 2.7.13.3 ko:K07652 ko02020,map02020 M00459 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,PAS,PAS_9 k141_37312_1 1385511.N783_07630 3.86e-43 146.0 COG1280@1|root,COG1280@2|Bacteria,1V1RZ@1239|Firmicutes,4IS1Q@91061|Bacilli 91061|Bacilli E LysE type translocator - - - - - - - - - - - - LysE k141_37312_2 265729.GS18_0207215 5.7e-81 241.0 COG3324@1|root,COG3324@2|Bacteria,1V48C@1239|Firmicutes,4HHTZ@91061|Bacilli,1ZFPT@1386|Bacillus 91061|Bacilli S enzyme related to lactoylglutathione lyase - - - ko:K06996 - - - - ko00000 - - - Glyoxalase k141_11333_2 1279017.AQYJ01000023_gene3246 1.06e-155 442.0 COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,1RMBU@1236|Gammaproteobacteria,465GA@72275|Alteromonadaceae 1236|Gammaproteobacteria H Belongs to the NadC ModD family nadC GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034213,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605 2.4.2.19 ko:K00767 ko00760,ko01100,map00760,map01100 M00115 R03348 RC02877 ko00000,ko00001,ko00002,ko01000 - - iECP_1309.ECP_0109 QRPTase_C,QRPTase_N k141_5381_1 218284.CCDN010000007_gene3828 1.8e-64 209.0 COG4853@1|root,COG4853@2|Bacteria,1V1FW@1239|Firmicutes,4HFWZ@91061|Bacilli,1ZDGV@1386|Bacillus 91061|Bacilli S protein conserved in bacteria yycI - - - - - - - - - - - YycI k141_24268_1 218284.CCDN010000007_gene3944 9.82e-130 371.0 COG1994@1|root,COG1994@2|Bacteria,1V6D4@1239|Firmicutes,4H9SF@91061|Bacilli,1ZCSE@1386|Bacillus 91061|Bacilli S Peptidase M50 ywhC - - - - - - - - - - - Peptidase_M50 k141_26931_1 760568.Desku_1621 1.56e-05 51.6 COG0305@1|root,COG0358@1|root,COG0305@2|Bacteria,COG0358@2|Bacteria,1UZ51@1239|Firmicutes,24CY5@186801|Clostridia 186801|Clostridia L DNA primase, catalytic core - - - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB_C,Toprim_2,zf-CHC2 k141_13789_1 218284.CCDN010000007_gene3819 4.24e-113 333.0 COG1226@1|root,COG1226@2|Bacteria,1TT0B@1239|Firmicutes,4HBDX@91061|Bacilli,1ZDQI@1386|Bacillus 91061|Bacilli P Ion channel kch - - ko:K10716 - - - - ko00000,ko02000 1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6 - - Ion_trans_2,TrkA_N k141_36090_2 1385514.N782_18290 1.3e-105 310.0 COG3833@1|root,COG3833@2|Bacteria,1TRB7@1239|Firmicutes,4HC5K@91061|Bacilli,2YA23@289201|Pontibacillus 91061|Bacilli U transporter permease malD GO:0003674,GO:0003824,GO:0005215,GO:0005363,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015154,GO:0015157,GO:0015399,GO:0015405,GO:0015422,GO:0015423,GO:0015766,GO:0015768,GO:0015772,GO:0015774,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0033037,GO:0034219,GO:0042623,GO:0042626,GO:0042956,GO:0043211,GO:0043492,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 - ko:K15772 ko02010,map02010 M00491 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.16,3.A.1.1.2 - - BPD_transp_1 k141_6527_1 765911.Thivi_3245 1.39e-78 242.0 COG2908@1|root,COG2908@2|Bacteria,1MVKD@1224|Proteobacteria,1RQIA@1236|Gammaproteobacteria,1WWVB@135613|Chromatiales 135613|Chromatiales S Calcineurin-like phosphoesterase superfamily domain - - - - - - - - - - - - Metallophos_2 k141_30130_1 1192034.CAP_4260 5.44e-44 155.0 COG1319@1|root,COG1319@2|Bacteria,1PG5C@1224|Proteobacteria,43EJH@68525|delta/epsilon subdivisions,2X9UI@28221|Deltaproteobacteria,2Z2GS@29|Myxococcales 28221|Deltaproteobacteria C CO dehydrogenase flavoprotein C-terminal domain - - 1.2.5.3 ko:K03519 - - R11168 RC02800 ko00000,ko01000 - - - CO_deh_flav_C,FAD_binding_5 k141_33843_2 1443125.Z962_p0039 3.24e-28 105.0 2ENX8@1|root,33GI6@2|Bacteria,1VJKN@1239|Firmicutes,24V7T@186801|Clostridia,36Q2G@31979|Clostridiaceae 186801|Clostridia - - - - - - - - - - - - - - - k141_33843_6 1147043.H9A0Z6_9CAUD 1.11e-16 77.4 4QB0W@10239|Viruses 10239|Viruses S Protein of unknown function (DUF1064) - - - - - - - - - - - - - k141_19596_1 218284.CCDN010000001_gene768 1.42e-06 54.7 2ECSV@1|root,336QF@2|Bacteria,1VFWG@1239|Firmicutes,4HP8Y@91061|Bacilli,1ZIWT@1386|Bacillus 91061|Bacilli S YqfQ-like protein yqfQ - - - - - - - - - - - YqfQ k141_31365_1 218284.CCDN010000007_gene3822 3.27e-112 334.0 COG0754@1|root,COG0754@2|Bacteria,1UTUT@1239|Firmicutes,4HBAJ@91061|Bacilli,1ZB3R@1386|Bacillus 91061|Bacilli E Glutathionylspermidine synthase preATP-grasp - - - - - - - - - - - - GSP_synth k141_18497_2 997296.PB1_06192 5.59e-30 115.0 COG0476@1|root,COG0476@2|Bacteria,1TQ3U@1239|Firmicutes,4HBGP@91061|Bacilli,1ZBR4@1386|Bacillus 91061|Bacilli H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 moeB - 2.7.7.73,2.7.7.80 ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07459 RC00043 ko00000,ko00001,ko01000 - - - ThiF k141_14750_1 279010.BL03321 9.21e-24 102.0 COG2211@1|root,COG2211@2|Bacteria,1UI0Q@1239|Firmicutes,4HENG@91061|Bacilli,1ZBFT@1386|Bacillus 91061|Bacilli G Transmembrane secretion effector - - - - - - - - - - - - MFS_3 k141_14750_2 1243664.CAVL020000003_gene938 1.49e-72 220.0 2CHCP@1|root,32S5R@2|Bacteria,1V3HI@1239|Firmicutes,4HGYA@91061|Bacilli,1ZFKK@1386|Bacillus 91061|Bacilli S Domain of unknown function (DU1801) - - - - - - - - - - - - DUF1801 k141_33867_1 1120998.AUFC01000037_gene1220 9.04e-09 57.8 COG1574@1|root,COG1574@2|Bacteria,1TQ6G@1239|Firmicutes,24A5F@186801|Clostridia 186801|Clostridia EG metal-dependent hydrolase with the TIM-barrel fold - - - - - - - - - - - - Amidohydro_3 k141_33867_2 218284.CCDN010000002_gene2133 4.98e-97 285.0 COG1670@1|root,COG1670@2|Bacteria,1V2C6@1239|Firmicutes,4HG3C@91061|Bacilli,1ZFP6@1386|Bacillus 91061|Bacilli J Acetyltransferase (GNAT) domain yoaA - 2.3.1.128 ko:K03790 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 k141_30143_1 1117379.BABA_26086 3.73e-45 161.0 COG0515@1|root,COG0515@2|Bacteria,1VBSJ@1239|Firmicutes,4HKRP@91061|Bacilli,1ZHE2@1386|Bacillus 91061|Bacilli KLT COG0515 Serine threonine protein kinase - - - - - - - - - - - - RIO1 k141_35067_1 1379270.AUXF01000003_gene3895 9.44e-110 350.0 COG0653@1|root,COG0653@2|Bacteria,1ZSMK@142182|Gemmatimonadetes 142182|Gemmatimonadetes U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA - - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW k141_37338_3 218284.CCDN010000001_gene1266 5.44e-119 349.0 COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1TPH9@1239|Firmicutes,4H9PW@91061|Bacilli,1ZBF9@1386|Bacillus 91061|Bacilli H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate ribBA GO:0003674,GO:0003824,GO:0003933,GO:0003935,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0019238,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.5.4.25,4.1.99.12 ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 M00125,M00840 R00425,R07281 RC00293,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS08945 DHBP_synthase,GTP_cyclohydro2 k141_10195_1 1078085.HMPREF1210_00657 1.64e-152 478.0 COG1404@1|root,COG2755@1|root,COG1404@2|Bacteria,COG2755@2|Bacteria,1TPH1@1239|Firmicutes,4HBQH@91061|Bacilli 91061|Bacilli O Belongs to the peptidase S8 family prtS - 3.4.21.110,3.4.21.96 ko:K01361,ko:K08652 - - - - ko00000,ko01000,ko01002,ko03110 - - - FIVAR,Gram_pos_anchor,Inhibitor_I9,PA,Peptidase_S8,SLH,YSIRK_signal,fn3_5 k141_2881_1 1217703.F904_00691 2.98e-20 92.0 COG1502@1|root,COG1502@2|Bacteria,1MUDJ@1224|Proteobacteria,1RMIF@1236|Gammaproteobacteria,3NK7J@468|Moraxellaceae 1236|Gammaproteobacteria I Phospholipase D - - - ko:K06132 ko00564,ko01100,map00564,map01100 - R11062 RC00017 ko00000,ko00001,ko01000 - - - PLDc_2 k141_36107_1 1232410.KI421424_gene1814 2.37e-172 502.0 COG0146@1|root,COG0146@2|Bacteria,1QU46@1224|Proteobacteria,43CGH@68525|delta/epsilon subdivisions,2WJ3J@28221|Deltaproteobacteria,43TNM@69541|Desulfuromonadales 28221|Deltaproteobacteria EQ Hydantoinase B/oxoprolinase hyuB - 3.5.2.14 ko:K01474 ko00330,ko01100,map00330,map01100 - R03187 RC00632 ko00000,ko00001,ko01000 - - - Hydantoinase_B k141_5411_1 42565.FP66_05230 3.4e-125 366.0 COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,1RMEN@1236|Gammaproteobacteria,1XHZY@135619|Oceanospirillales 135619|Oceanospirillales U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - - - - - - - - - - SDF k141_32530_1 1117647.M5M_06210 9.58e-114 339.0 COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,1RS1D@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Creatinase/Prolidase N-terminal domain - - 3.4.13.9 ko:K01271 - - - - ko00000,ko01000,ko01002 - - - Creatinase_N,Peptidase_M24 k141_24285_1 527002.yaldo0001_24880 6.07e-11 63.2 COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,1RMHI@1236|Gammaproteobacteria,41F6E@629|Yersinia 1236|Gammaproteobacteria U Belongs to the peptidase S26 family lepB GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009987,GO:0010467,GO:0015643,GO:0016020,GO:0016021,GO:0016485,GO:0016787,GO:0017171,GO:0019538,GO:0031224,GO:0031226,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24,Peptidase_S26 k141_24285_2 861299.J421_2922 1.98e-78 241.0 COG0568@1|root,COG0568@2|Bacteria,1ZSR6@142182|Gemmatimonadetes 142182|Gemmatimonadetes K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released - - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 k141_23256_2 218284.CCDN010000001_gene1190 2.59e-58 186.0 COG1418@1|root,COG1418@2|Bacteria,1V7IZ@1239|Firmicutes,4HIVB@91061|Bacilli,1ZB0E@1386|Bacillus 91061|Bacilli S phosphohydrolase ypgQ - - ko:K06950 - - - - ko00000 - - - HD k141_19621_1 218284.CCDN010000004_gene3087 2.38e-38 130.0 COG1495@1|root,COG1495@2|Bacteria,1V79S@1239|Firmicutes,4HH9B@91061|Bacilli,1ZRVX@1386|Bacillus 91061|Bacilli O Required for disulfide bond formation in some proteins bdbC - - ko:K03611 - - - - ko00000,ko03110 5.A.2.1 - - DsbB k141_19621_2 218284.CCDN010000004_gene3089 1.03e-149 432.0 COG0388@1|root,COG3153@1|root,COG0388@2|Bacteria,COG3153@2|Bacteria,1TQAZ@1239|Firmicutes,4HCQW@91061|Bacilli,1ZB16@1386|Bacillus 91061|Bacilli K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase yhcX - - - - - - - - - - - Acetyltransf_1,CN_hydrolase k141_11361_1 218284.CCDN010000001_gene673 5.01e-116 337.0 COG1179@1|root,COG1179@2|Bacteria,1TQ7A@1239|Firmicutes,4H9KZ@91061|Bacilli,1ZBGG@1386|Bacillus 91061|Bacilli H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 yrvM GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016829,GO:0016835,GO:0016836,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0061503,GO:0061504,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 - ko:K22132 - - - - ko00000,ko03016 - - - ThiF k141_18498_1 218284.CCDN010000008_gene4150 4.43e-136 396.0 COG1271@1|root,COG1271@2|Bacteria,1TRH4@1239|Firmicutes,4HA19@91061|Bacilli,1ZBAG@1386|Bacillus 91061|Bacilli C oxidase, subunit ythA - 1.10.3.14 ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - Cyt_bd_oxida_I k141_18498_2 218284.CCDN010000008_gene4149 1.24e-47 161.0 COG1294@1|root,COG1294@2|Bacteria,1TPYX@1239|Firmicutes,4HA9T@91061|Bacilli,1ZCH6@1386|Bacillus 91061|Bacilli C COG1294 Cytochrome bd-type quinol oxidase, subunit 2 ythB - 1.10.3.14 ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - Cyt_bd_oxida_II k141_701_1 218284.CCDN010000005_gene3359 2.22e-14 72.4 2E3R1@1|root,32YNU@2|Bacteria,1VEND@1239|Firmicutes,4HNII@91061|Bacilli,1ZFAW@1386|Bacillus 91061|Bacilli S Anti-sigma factor N-terminus rsgI - - - - - - - - - - - RsgI_N k141_701_2 218284.CCDN010000005_gene3358 8.12e-113 328.0 COG1191@1|root,COG1191@2|Bacteria,1V5E6@1239|Firmicutes,4HEBS@91061|Bacilli,1ZCY4@1386|Bacillus 91061|Bacilli K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released sigI - - ko:K03093 - - - - ko00000,ko03021 - - - Sigma70_r2 k141_21943_1 861299.J421_2771 1.67e-29 116.0 COG0480@1|root,COG0480@2|Bacteria,1ZT9G@142182|Gemmatimonadetes 142182|Gemmatimonadetes J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome fusA - - ko:K02355 - - - - ko00000,ko03012,ko03029 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 k141_21943_2 1499967.BAYZ01000113_gene2944 2.74e-240 665.0 COG0050@1|root,COG0050@2|Bacteria,2NNQV@2323|unclassified Bacteria 2|Bacteria J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis tuf - - ko:K02358 - - - - ko00000,ko03012,ko03029,ko04147 - - - GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 k141_21943_3 1137799.GZ78_25460 4.94e-12 61.6 COG0051@1|root,COG0051@2|Bacteria,1RGWF@1224|Proteobacteria,1S3QX@1236|Gammaproteobacteria,1XJXE@135619|Oceanospirillales 135619|Oceanospirillales J Involved in the binding of tRNA to the ribosomes rpsJ - - ko:K02946 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S10 k141_1660_1 42565.FP66_10150 3.51e-151 430.0 COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,1RPR7@1236|Gammaproteobacteria,1XI4E@135619|Oceanospirillales 135619|Oceanospirillales H Belongs to the FPP GGPP synthase family ispB - 2.5.1.90 ko:K02523 ko00900,ko01110,map00900,map01110 - R09248 RC00279 ko00000,ko00001,ko01000,ko01006 - - - polyprenyl_synt k141_4170_1 1453501.JELR01000002_gene1220 1.7e-78 239.0 COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,1RP3J@1236|Gammaproteobacteria,464SQ@72275|Alteromonadaceae 1236|Gammaproteobacteria L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates fpg GO:0000702,GO:0000703,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003824,GO:0003906,GO:0004518,GO:0004519,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008270,GO:0008534,GO:0009987,GO:0016787,GO:0016788,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.2.2.23,4.2.99.18 ko:K10563 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Fapy_DNA_glyco,H2TH,zf-FPG_IleRS k141_4170_3 1453501.JELR01000002_gene1218 2.02e-47 152.0 COG0227@1|root,COG0227@2|Bacteria,1MZ57@1224|Proteobacteria,1S8UG@1236|Gammaproteobacteria,467R5@72275|Alteromonadaceae 1236|Gammaproteobacteria J Belongs to the bacterial ribosomal protein bL28 family rpmB GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02902 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L28 k141_11362_1 720555.BATR1942_11190 1.25e-22 92.8 COG1191@1|root,COG1191@2|Bacteria,1TPJ5@1239|Firmicutes,4HBY2@91061|Bacilli,1ZB3Q@1386|Bacillus 91061|Bacilli K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released sigK GO:0000003,GO:0000988,GO:0000990,GO:0003674,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043254,GO:0043934,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - ko:K03091 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4 k141_35069_1 218284.CCDN010000004_gene3027 1.98e-104 302.0 COG2172@1|root,COG2172@2|Bacteria,1V1IA@1239|Firmicutes,4HFPF@91061|Bacilli,1ZF6G@1386|Bacillus 91061|Bacilli T Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B) rsbW GO:0000988,GO:0000989,GO:0003674,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 2.7.11.1 ko:K04757 - - - - ko00000,ko01000,ko01001,ko03021 - - - HATPase_c_2 k141_19622_1 1294265.JCM21738_2037 2.38e-113 335.0 2C2CG@1|root,2Z7PW@2|Bacteria,1TQQ2@1239|Firmicutes,4H9UX@91061|Bacilli,1ZCFI@1386|Bacillus 91061|Bacilli S stage III sporulation protein AE spoIIIAE - - ko:K06394 - - - - ko00000 - - - Spore_III_AE k141_33869_1 1042377.AFPJ01000038_gene1100 1.14e-58 201.0 COG4774@1|root,COG4774@2|Bacteria,1NMCN@1224|Proteobacteria,1T3TQ@1236|Gammaproteobacteria,46DC7@72275|Alteromonadaceae 1236|Gammaproteobacteria P TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_10196_1 1120950.KB892709_gene4038 3.41e-72 236.0 COG3211@1|root,COG3211@2|Bacteria,2GJKE@201174|Actinobacteria,4DNUN@85009|Propionibacteriales 201174|Actinobacteria S Bacterial protein of unknown function (DUF839) - - - ko:K07093 - - - - ko00000 - - - DUF839 k141_702_1 326297.Sama_1872 3.33e-16 81.6 COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,1MWPN@1224|Proteobacteria,1RYA9@1236|Gammaproteobacteria,2Q9S0@267890|Shewanellaceae 1236|Gammaproteobacteria T histidine kinase, dimerisation and phosphoacceptor region hrpX - - - - - - - - - - - HATPase_c,HisKA_3,PAS,PAS_4,PAS_9 k141_37341_1 1123321.KB905820_gene5668 8.54e-37 135.0 COG3509@1|root,COG3509@2|Bacteria,2GMTA@201174|Actinobacteria 201174|Actinobacteria Q Esterase, phb depolymerase family phaZ1 - - - - - - - - - - - Esterase_phd k141_24287_1 491915.Aflv_0923 1.03e-12 64.7 COG1321@1|root,COG1321@2|Bacteria,1V3IS@1239|Firmicutes,4HH06@91061|Bacilli,21VNJ@150247|Anoxybacillus 91061|Bacilli K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon mntR - - ko:K03709 - - - - ko00000,ko03000 - - - Fe_dep_repr_C,Fe_dep_repress,FeoA k141_35354_1 443218.AS9A_3138 1.23e-20 92.4 COG0789@1|root,COG0789@2|Bacteria,2HBV6@201174|Actinobacteria,232TE@1762|Mycobacteriaceae 201174|Actinobacteria K Transcriptional regulator merR1 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - - - - - - - - - - MerR,MerR_1 k141_27259_1 1042377.AFPJ01000024_gene716 8.37e-98 293.0 COG0611@1|root,COG0611@2|Bacteria,1MU9X@1224|Proteobacteria,1RNHU@1236|Gammaproteobacteria,466CJ@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 thiL GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009030,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009229,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042357,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.16 ko:K00946 ko00730,ko01100,map00730,map01100 M00127 R00617 RC00002 ko00000,ko00001,ko00002,ko01000 - - iSFV_1184.SFV_0382 AIRS,AIRS_C k141_23573_1 1336233.JAEH01000051_gene4067 0.000159 50.1 COG1572@1|root,COG3291@1|root,COG1572@2|Bacteria,COG3291@2|Bacteria,1RF0V@1224|Proteobacteria,1SWW0@1236|Gammaproteobacteria,2QD9X@267890|Shewanellaceae 1236|Gammaproteobacteria O Matrixin - - - - - - - - - - - - PKD,Peptidase_M10 k141_34098_1 1042377.AFPJ01000012_gene1389 9.54e-40 140.0 COG1612@1|root,COG1612@2|Bacteria,1MVJ4@1224|Proteobacteria,1RQWB@1236|Gammaproteobacteria,463XT@72275|Alteromonadaceae 1236|Gammaproteobacteria O protein required for cytochrome oxidase assembly ctaA - - ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 M00154 R07412 RC00769 ko00000,ko00001,ko00002,ko03029 3.D.4.4 - - COX15-CtaA k141_9251_1 106370.Francci3_2197 1.52e-18 90.9 COG3344@1|root,COG3344@2|Bacteria,2GUJS@201174|Actinobacteria 201174|Actinobacteria L RNA-directed DNA polymerase (reverse transcriptase) - - 2.7.7.49 ko:K00986 - - - - ko00000,ko01000 - - - GIIM,RVT_1 k141_3102_1 745411.B3C1_19133 5.88e-64 205.0 COG3547@1|root,COG3547@2|Bacteria,1MXKJ@1224|Proteobacteria,1RSCP@1236|Gammaproteobacteria,1J7B8@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L Transposase Z012_08285 - - ko:K07486 - - - - ko00000 - - - DEDD_Tnp_IS110,Transposase_20 k141_7882_1 218284.CCDN010000007_gene3986 3.53e-39 140.0 COG0840@1|root,COG0840@2|Bacteria,1TPI1@1239|Firmicutes,4HADY@91061|Bacilli,1ZD20@1386|Bacillus 91061|Bacilli NT Chemotaxis mcpA - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal k141_11632_1 218284.CCDN010000001_gene270 2.8e-97 303.0 COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,4H9SP@91061|Bacilli,1ZAPS@1386|Bacillus 91061|Bacilli P COG2217 Cation transport ATPase cadA - 3.6.3.3,3.6.3.5 ko:K01534 - - - - ko00000,ko01000 3.A.3.6 - - E1-E2_ATPase,HMA,Hydrolase k141_37508_2 1032480.MLP_44990 7.48e-11 60.8 2E3U2@1|root,32YRF@2|Bacteria,2GSNJ@201174|Actinobacteria,4DSFY@85009|Propionibacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - k141_20908_1 935837.JAEK01000006_gene4240 1.27e-55 182.0 COG3711@1|root,COG3711@2|Bacteria,1TT5A@1239|Firmicutes,4HC5Y@91061|Bacilli,1ZDB0@1386|Bacillus 91061|Bacilli K transcriptional antiterminator sacT - - ko:K03488 - - - - ko00000,ko03000 - - - CAT_RBD,PRD k141_32785_1 643867.Ftrac_3709 4.47e-20 90.9 COG0438@1|root,COG0438@2|Bacteria,4NJ6W@976|Bacteroidetes,47N47@768503|Cytophagia 976|Bacteroidetes M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_trans_1_4,Glycos_transf_1 k141_27260_1 218284.CCDN010000007_gene3969 3.3e-141 402.0 COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,4H9ZU@91061|Bacilli,1ZBBA@1386|Bacillus 91061|Bacilli G Aldolase fbaA - 4.1.2.13 ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS11075 F_bP_aldolase k141_25907_2 665952.HMPREF1015_00809 3.01e-40 139.0 COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,4HBFV@91061|Bacilli,1ZD4X@1386|Bacillus 91061|Bacilli J Belongs to the RNA methyltransferase TrmD family trmD GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 ko:K00554 - - R00597 RC00003,RC00334 ko00000,ko01000,ko03016 - - - tRNA_m1G_MT k141_7883_1 218284.CCDN010000002_gene2780 6.13e-94 282.0 COG0840@1|root,COG0840@2|Bacteria,1TQNQ@1239|Firmicutes,4HD0J@91061|Bacilli,1ZDDE@1386|Bacillus 91061|Bacilli NT PAS fold - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - MCPsignal,PAS_3,PAS_4,PAS_9 k141_23574_2 1294265.JCM21738_1801 6.65e-160 458.0 COG3314@1|root,COG3314@2|Bacteria,1TR35@1239|Firmicutes,4HAB6@91061|Bacilli,1ZARZ@1386|Bacillus 91061|Bacilli S protein conserved in bacteria - - - - - - - - - - - - Gate k141_6812_1 1294265.JCM21738_4540 1.64e-20 87.8 COG0739@1|root,COG0739@2|Bacteria,1TQMQ@1239|Firmicutes,4HC7V@91061|Bacilli,1ZAQT@1386|Bacillus 91061|Bacilli M Peptidase, M23 lytH - - ko:K21472 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_M23 k141_6812_2 1294265.JCM21738_4541 7.36e-76 240.0 COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,4HAAI@91061|Bacilli,1ZBC5@1386|Bacillus 91061|Bacilli S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family - - - ko:K03308 - - - - ko00000 2.A.22.4,2.A.22.5 - - SNF k141_896_1 218284.CCDN010000005_gene3165 6.7e-246 681.0 COG1668@1|root,COG1668@2|Bacteria,1TXRK@1239|Firmicutes,4HC9K@91061|Bacilli,1ZBM6@1386|Bacillus 91061|Bacilli CP COG1668 ABC-type Na efflux pump, permease component yhaP - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 k141_35356_1 218284.CCDN010000001_gene1302 4.63e-134 392.0 COG0477@1|root,COG2814@2|Bacteria,1VSW8@1239|Firmicutes,4HUQC@91061|Bacilli,1ZAS8@1386|Bacillus 91061|Bacilli EGP the major facilitator superfamily mdr GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - - - - - - - - - - MFS_1 k141_19881_2 406124.ACPC01000046_gene2410 1.46e-63 199.0 COG3708@1|root,COG3708@2|Bacteria,1VB3W@1239|Firmicutes,4HKQB@91061|Bacilli,1ZG5P@1386|Bacillus 91061|Bacilli K Integron-associated effector binding protein - - - - - - - - - - - - Cass2,GyrI-like k141_19881_3 1238184.CM001792_gene273 8.34e-10 56.2 COG0346@1|root,COG0346@2|Bacteria,1V7AX@1239|Firmicutes,4HJ5Z@91061|Bacilli,23KU9@182709|Oceanobacillus 91061|Bacilli E lactoylglutathione lyase activity - - - - - - - - - - - - Glyoxalase k141_27261_1 1453501.JELR01000001_gene2016 4.73e-134 400.0 COG4776@1|root,COG4776@2|Bacteria,1P563@1224|Proteobacteria,1RP5G@1236|Gammaproteobacteria,46DF9@72275|Alteromonadaceae 1236|Gammaproteobacteria K RNB rnb GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0008859,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360,GO:1901361,GO:1901575 3.1.13.1 ko:K01147 - - - - ko00000,ko01000,ko03016 - - - OB_RNB,RNB,S1 k141_7884_1 406124.ACPC01000049_gene158 5.22e-20 84.0 COG0537@1|root,COG0537@2|Bacteria,1V6UE@1239|Firmicutes,4HJ7C@91061|Bacilli,1ZGZR@1386|Bacillus 91061|Bacilli FG Scavenger mRNA decapping enzyme C-term binding - - - - - - - - - - - - HIT k141_7884_2 1227349.C170_13590 1.66e-05 48.1 COG1247@1|root,COG1247@2|Bacteria,1UNI5@1239|Firmicutes,4IUF3@91061|Bacilli,275WQ@186822|Paenibacillaceae 91061|Bacilli M FR47-like protein - - - - - - - - - - - - Acetyltransf_1 k141_9254_2 218284.CCDN010000005_gene3445 6.84e-81 252.0 COG0651@1|root,COG0651@2|Bacteria,1TRAT@1239|Firmicutes,4HA10@91061|Bacilli,1ZB2A@1386|Bacillus 91061|Bacilli CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali mrpD GO:0003674,GO:0005215,GO:0005451,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015491,GO:0015672,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0035725,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0098655,GO:0098660,GO:0098662,GO:0099516,GO:1902600 - ko:K05568 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - iSB619.SA_RS04615 Proton_antipo_M k141_36289_3 1453501.JELR01000002_gene95 1.1e-45 149.0 COG2142@1|root,COG2142@2|Bacteria,1MZR9@1224|Proteobacteria,1S9TS@1236|Gammaproteobacteria,467WQ@72275|Alteromonadaceae 1236|Gammaproteobacteria C Membrane-anchoring subunit of succinate dehydrogenase (SDH) sdhD GO:0000104,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0016999,GO:0017004,GO:0017144,GO:0019752,GO:0020037,GO:0022607,GO:0022900,GO:0032991,GO:0034622,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0065003,GO:0070469,GO:0070470,GO:0071704,GO:0071840,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901363,GO:1902494,GO:1990204 - ko:K00242 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173 R02164 RC00045 ko00000,ko00001,ko00002 - - e_coli_core.b0722,iAF1260.b0722,iAPECO1_1312.APECO1_1356,iB21_1397.B21_00671,iBWG_1329.BWG_0581,iE2348C_1286.E2348C_0602,iEC042_1314.EC042_0740,iECABU_c1320.ECABU_c07680,iECBD_1354.ECBD_2938,iECB_1328.ECB_00682,iECDH10B_1368.ECDH10B_0789,iECDH1ME8569_1439.ECDH1ME8569_0681,iECD_1391.ECD_00682,iECED1_1282.ECED1_0692,iECIAI1_1343.ECIAI1_0696,iECIAI39_1322.ECIAI39_0680,iECNA114_1301.ECNA114_0658,iECO103_1326.ECO103_0716,iECO111_1330.ECO111_0739,iECO26_1355.ECO26_0783,iECOK1_1307.ECOK1_0722,iECP_1309.ECP_0734,iECS88_1305.ECS88_0748,iECSE_1348.ECSE_0782,iECSF_1327.ECSF_0655,iECUMN_1333.ECUMN_0800,iECW_1372.ECW_m0777,iEKO11_1354.EKO11_3157,iETEC_1333.ETEC_0733,iEcDH1_1363.EcDH1_2913,iEcE24377_1341.EcE24377A_0749,iEcHS_1320.EcHS_A0770,iEcSMS35_1347.EcSMS35_0735,iEcolC_1368.EcolC_2933,iJO1366.b0722,iJR904.b0722,iLF82_1304.LF82_2100,iNRG857_1313.NRG857_03215,iSBO_1134.SBO_0580,iSDY_1059.SDY_0660,iSFV_1184.SFV_0613,iSF_1195.SF0575,iSFxv_1172.SFxv_0634,iSSON_1240.SSON_0673,iS_1188.S0588,iUMN146_1321.UM146_14010,iUMNK88_1353.UMNK88_758,iUTI89_1310.UTI89_C0718,iWFL_1372.ECW_m0777,iY75_1357.Y75_RS03755,ic_1306.c0800 Sdh_cyt k141_3104_1 1211814.CAPG01000024_gene862 1.24e-27 113.0 COG0640@1|root,COG0640@2|Bacteria,1V5AM@1239|Firmicutes,4IDGZ@91061|Bacilli,1ZFWA@1386|Bacillus 91061|Bacilli K helix_turn_helix, Arsenical Resistance Operon Repressor - - - - - - - - - - - - HTH_5 k141_23576_1 218284.CCDN010000003_gene2989 9.47e-122 379.0 COG1197@1|root,COG1197@2|Bacteria,1TPF1@1239|Firmicutes,4H9NB@91061|Bacilli,1ZBAK@1386|Bacillus 91061|Bacilli L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd - - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF k141_25908_1 1453501.JELR01000002_gene890 6.62e-103 336.0 COG1652@1|root,COG3210@1|root,COG1652@2|Bacteria,COG3210@2|Bacteria,1MXIP@1224|Proteobacteria,1RSAX@1236|Gammaproteobacteria,468YR@72275|Alteromonadaceae 1236|Gammaproteobacteria U haemagglutination activity domain Z012_01725 GO:0005575,GO:0005576 - - - - - - - - - - ESPR,Glug,Haemagg_act k141_27262_1 218284.CCDN010000001_gene1723 7.03e-40 143.0 COG1075@1|root,COG1075@2|Bacteria,1TQFF@1239|Firmicutes,4HDQN@91061|Bacilli,1ZCCU@1386|Bacillus 91061|Bacilli S acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - - - - - - - - - - PGAP1 k141_27262_2 218284.CCDN010000001_gene1724 6.5e-39 130.0 COG1695@1|root,COG1695@2|Bacteria,1V8K6@1239|Firmicutes,4HJY6@91061|Bacilli,1ZHGP@1386|Bacillus 91061|Bacilli K Transcriptional regulator PadR-like family - - - - - - - - - - - - PadR k141_22249_1 218284.CCDN010000001_gene1872 0.000541 41.6 COG0740@1|root,COG0740@2|Bacteria,1TPX2@1239|Firmicutes,4H9XG@91061|Bacilli,1ZBH5@1386|Bacillus 91061|Bacilli OU COG0740 Protease subunit of ATP-dependent Clp proteases tepA - - - - - - - - - - - CLP_protease k141_22249_2 666686.B1NLA3E_06725 7.2e-21 84.3 2DR6C@1|root,33ACS@2|Bacteria,1VM75@1239|Firmicutes,4HR6M@91061|Bacilli,1ZJYN@1386|Bacillus 91061|Bacilli S YlzJ-like protein - - - - - - - - - - - - YlzJ k141_22249_3 218284.CCDN010000001_gene1870 1.78e-65 219.0 COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,4H9WA@91061|Bacilli,1ZANX@1386|Bacillus 91061|Bacilli D Belongs to the FtsK SpoIIIE SftA family ftsK GO:0000003,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma k141_11635_1 379066.GAU_1434 8.78e-83 254.0 COG0745@1|root,COG0745@2|Bacteria,1ZUFQ@142182|Gemmatimonadetes 142182|Gemmatimonadetes K Transcriptional regulatory protein, C terminal - - - - - - - - - - - - Response_reg,Trans_reg_C k141_11635_2 745411.B3C1_08556 3.88e-18 87.8 COG0642@1|root,COG0642@2|Bacteria,1QTSX@1224|Proteobacteria,1T1G3@1236|Gammaproteobacteria,1JC2S@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria T Two-component sensor kinase N-terminal qseC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 ko:K07645 ko02020,ko02024,map02020,map02024 M00453 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - 2CSK_N,HATPase_c,HisKA k141_19882_1 1294265.JCM21738_3300 2.89e-88 268.0 COG4864@1|root,COG4864@2|Bacteria,1TPTD@1239|Firmicutes,4HAIX@91061|Bacilli,1ZD1V@1386|Bacillus 91061|Bacilli S UPF0365 protein yqfA - - - - - - - - - - - YdfA_immunity k141_31475_1 675814.VIC_001634 5.49e-207 622.0 COG0457@1|root,COG0457@2|Bacteria,1QWBQ@1224|Proteobacteria,1T2T1@1236|Gammaproteobacteria,1XW90@135623|Vibrionales 135623|Vibrionales S Bacteriophage N adsorption protein A C-term - - - ko:K11739 - - - - ko00000 - - - NfrA_C k141_17362_1 218284.CCDN010000001_gene549 2.31e-134 385.0 COG0566@1|root,COG0566@2|Bacteria,1V3JP@1239|Firmicutes,4HCF5@91061|Bacilli,1ZBTY@1386|Bacillus 91061|Bacilli J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family spoU - - ko:K03437 - - - - ko00000,ko03016 - - - SpoU_methylase,SpoU_sub_bind k141_5693_1 1279017.AQYJ01000029_gene3328 3.39e-72 236.0 COG0665@1|root,COG4121@1|root,COG0665@2|Bacteria,COG4121@2|Bacteria,1MZW5@1224|Proteobacteria,1RMTE@1236|Gammaproteobacteria,464VK@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 mnmC GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0004808,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016491,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363 2.1.1.61 ko:K15461 - - R00601,R08702 RC00003,RC00053,RC00060,RC01483 ko00000,ko01000,ko03016 - - - DAO,Methyltransf_30 k141_5693_2 1453501.JELR01000001_gene2728 2.17e-111 324.0 COG2928@1|root,COG2928@2|Bacteria,1RF26@1224|Proteobacteria,1S579@1236|Gammaproteobacteria,46AQV@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF502) - - - - - - - - - - - - DUF502 k141_5693_3 1279017.AQYJ01000029_gene3326 2.4e-116 342.0 COG3823@1|root,COG3823@2|Bacteria,1R9YU@1224|Proteobacteria,1RZ5N@1236|Gammaproteobacteria,4679T@72275|Alteromonadaceae 1236|Gammaproteobacteria O Glutamine cyclotransferase - - 2.3.2.5 ko:K00683 - - - - ko00000,ko01000 - - - Glu_cyclase_2 k141_5693_5 1279017.AQYJ01000029_gene3324 0.0 946.0 COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,1RMPG@1236|Gammaproteobacteria,464P1@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG0514 Superfamily II DNA helicase recQ - 3.6.4.12 ko:K03654 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind k141_6814_1 218284.CCDN010000005_gene3470 2.09e-117 349.0 COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,4HC5M@91061|Bacilli,1ZB0M@1386|Bacillus 91061|Bacilli KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains rocR GO:0006082,GO:0006355,GO:0006520,GO:0006525,GO:0006807,GO:0008150,GO:0008152,GO:0009064,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031326,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1901564,GO:1901605,GO:1903506,GO:2000112,GO:2001141 - ko:K06714 - - - - ko00000,ko03000 - - - HTH_8,PAS,PAS_4,PAS_9,Sigma54_activat k141_899_1 1294265.JCM21738_5016 9.8e-81 247.0 COG2207@1|root,COG3708@1|root,COG2207@2|Bacteria,COG3708@2|Bacteria,1TQDS@1239|Firmicutes,4HH2S@91061|Bacilli,1ZC3G@1386|Bacillus 91061|Bacilli K AraC family transcriptional regulator - - - ko:K13653 - - - - ko00000,ko03000 - - - Cass2,HTH_18 k141_20910_1 28444.JODQ01000012_gene3385 1.51e-19 90.1 COG4221@1|root,COG4221@2|Bacteria,2GRRV@201174|Actinobacteria,4EFQ6@85012|Streptosporangiales 201174|Actinobacteria S KR domain - - - - - - - - - - - - adh_short k141_3105_1 1124983.PFLCHA0_c46330 1.97e-73 234.0 COG4941@1|root,COG4941@2|Bacteria,1MU3D@1224|Proteobacteria,1RN25@1236|Gammaproteobacteria,1YM35@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria K Belongs to the sigma-70 factor family - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2,TPR_2 k141_9255_1 1157708.KB907452_gene3970 3.93e-20 95.5 COG1181@1|root,COG1181@2|Bacteria,1QWAW@1224|Proteobacteria,2VITI@28216|Betaproteobacteria,4ABKK@80864|Comamonadaceae 28216|Betaproteobacteria M RimK-like ATP-grasp domain cphA2 - 6.3.2.29,6.3.2.30 ko:K03802 - - - - ko00000,ko01000 - - - CPSase_L_D2,Mur_ligase_C,Mur_ligase_M,RimK k141_9255_2 1042377.AFPJ01000042_gene1094 2.2e-36 132.0 COG1305@1|root,COG1305@2|Bacteria,1NEY1@1224|Proteobacteria,1SF7F@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Transglutaminase-like superfamily - - - - - - - - - - - - Transglut_core k141_32787_1 983545.Glaag_0641 4.09e-06 48.5 COG1778@1|root,COG1778@2|Bacteria,1RH85@1224|Proteobacteria,1S6D0@1236|Gammaproteobacteria,467ND@72275|Alteromonadaceae 1236|Gammaproteobacteria S Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate kdsC GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008781,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016311,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016791,GO:0019143,GO:0033692,GO:0034637,GO:0034645,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0070567,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 3.1.3.45 ko:K03270 ko00540,ko01100,map00540,map01100 M00063 R03350 RC00017 ko00000,ko00001,ko00002,ko01000,ko01005 - - iECO26_1355.ECO26_4302 Hydrolase_3 k141_32787_2 1121451.DESAM_21969 9.33e-73 228.0 COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,42M61@68525|delta/epsilon subdivisions,2WIXU@28221|Deltaproteobacteria,2M90H@213115|Desulfovibrionales 28221|Deltaproteobacteria M 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase kdsA - 2.5.1.55 ko:K01627 ko00540,ko01100,map00540,map01100 M00063 R03254 RC00435 ko00000,ko00001,ko00002,ko01000,ko01005 - - - DAHP_synth_1 k141_7886_1 253839.SSNG_05553 1.55e-25 108.0 COG0006@1|root,COG0006@2|Bacteria,2GM7D@201174|Actinobacteria 201174|Actinobacteria E Belongs to the peptidase M24B family - - 3.4.13.9 ko:K01271,ko:K01274 - - - - ko00000,ko01000,ko01002 - - - Creatinase_N,Peptidase_M24 k141_36290_1 218284.CCDN010000001_gene1164 5.11e-104 319.0 COG1199@1|root,COG1199@2|Bacteria,1TRNV@1239|Firmicutes,4HBYD@91061|Bacilli,1ZARY@1386|Bacillus 91061|Bacilli KL COG1199 Rad3-related DNA helicases ypvA - 3.6.4.12 ko:K03722 - - - - ko00000,ko01000,ko03400 - - - Helicase_C_2 k141_14997_1 1279017.AQYJ01000022_gene2729 4.07e-128 375.0 COG0349@1|root,COG0349@2|Bacteria,1MURV@1224|Proteobacteria,1RPBP@1236|Gammaproteobacteria,464UE@72275|Alteromonadaceae 1236|Gammaproteobacteria J Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides rnd GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0033890,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360 3.1.13.5 ko:K03684 - - - - ko00000,ko01000,ko03016 - - - DNA_pol_A_exo1,HRDC k141_14997_2 1042377.AFPJ01000052_gene1575 2.54e-36 124.0 COG3100@1|root,COG3100@2|Bacteria,1N83J@1224|Proteobacteria,1SCCD@1236|Gammaproteobacteria,468IY@72275|Alteromonadaceae 1236|Gammaproteobacteria S YcgL domain-containing protein ycgL - - ko:K09902 - - - - ko00000 - - - YcgL k141_14997_3 991905.SL003B_2939 2.11e-63 198.0 COG2983@1|root,COG2983@2|Bacteria,1RHMX@1224|Proteobacteria,2U99S@28211|Alphaproteobacteria,4BS5F@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria S Putative zinc- or iron-chelating domain MA20_15575 - - ko:K09160 - - - - ko00000 - - - CxxCxxCC k141_35358_1 1042377.AFPJ01000009_gene322 5.76e-179 527.0 COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,1RND3@1236|Gammaproteobacteria,4658W@72275|Alteromonadaceae 1236|Gammaproteobacteria E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor gcvP GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019464,GO:0019752,GO:0032991,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902494,GO:1990204 1.4.4.2 ko:K00281,ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko00002,ko01000 - - - GDC-P k141_23577_1 1453501.JELR01000002_gene1323 2.14e-79 247.0 COG0810@1|root,COG0810@2|Bacteria,1R65W@1224|Proteobacteria,1S133@1236|Gammaproteobacteria,466F5@72275|Alteromonadaceae 1236|Gammaproteobacteria M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - - - - - - - - - - - k141_23577_2 1202962.KB907152_gene1268 1.54e-59 186.0 COG3651@1|root,COG3651@2|Bacteria,1RH68@1224|Proteobacteria,1S7KX@1236|Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria - - - ko:K09966 - - - - ko00000 - - - DUF2237 k141_23577_3 1279017.AQYJ01000028_gene2066 2.25e-29 112.0 2DMKM@1|root,32S7K@2|Bacteria,1NH6E@1224|Proteobacteria 1224|Proteobacteria S Protein of unknown function (DUF2939) - - - - - - - - - - - - DUF2939 k141_900_1 218284.CCDN010000001_gene124 2.3e-141 404.0 COG3336@1|root,COG3336@2|Bacteria,1TQFK@1239|Firmicutes,4H9WN@91061|Bacilli,1ZBC8@1386|Bacillus 91061|Bacilli S cytochrome c oxidase ctaG - - ko:K02862 - - - - ko00000 - - - Caa3_CtaG k141_27263_1 298386.PBPRB1294 9.83e-54 173.0 2B8N8@1|root,321XP@2|Bacteria,1RHYW@1224|Proteobacteria,1S7J2@1236|Gammaproteobacteria,1XXT5@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_27263_2 1123053.AUDG01000121_gene824 2.75e-77 237.0 2DC1I@1|root,2ZCFR@2|Bacteria,1RBUV@1224|Proteobacteria,1S24Y@1236|Gammaproteobacteria,1X1ZY@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - k141_6815_1 379731.PST_4076 4.11e-80 250.0 COG0604@1|root,COG0604@2|Bacteria,1MWRK@1224|Proteobacteria,1SYCA@1236|Gammaproteobacteria,1YZNW@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases qor - 1.6.5.5 ko:K00344 - - - - ko00000,ko01000 - - - ADH_N,ADH_zinc_N k141_29298_26 1116375.VEJY3_02390 8.89e-60 184.0 COG0640@1|root,COG0640@2|Bacteria,1N72Q@1224|Proteobacteria,1SCH5@1236|Gammaproteobacteria,1XXWQ@135623|Vibrionales 135623|Vibrionales K transcriptional regulators hlyU GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - ko:K22042 - - - - ko00000,ko03000 - - - HTH_5 k141_29298_27 1219076.N646_2682 7.03e-47 151.0 COG0268@1|root,COG0268@2|Bacteria,1MZ94@1224|Proteobacteria,1S9AI@1236|Gammaproteobacteria,1XXVB@135623|Vibrionales 135623|Vibrionales J Binds directly to 16S ribosomal RNA rpsT GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02968 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S20p k141_29298_28 1116375.VEJY3_02400 0.0 960.0 COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,1RMXX@1236|Gammaproteobacteria,1XTUG@135623|Vibrionales 135623|Vibrionales U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane murJ GO:0000270,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0006869,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0010876,GO:0015647,GO:0015648,GO:0015835,GO:0015836,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0030203,GO:0031224,GO:0031226,GO:0033036,GO:0034204,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0061024,GO:0065007,GO:0065008,GO:0070589,GO:0071554,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0071944,GO:0097035,GO:1901135,GO:1901137,GO:1901264,GO:1901505,GO:1901564,GO:1901566,GO:1901576 - ko:K03980 - - - - ko00000,ko01011,ko02000 2.A.66.4 - - MVIN k141_29298_29 1116375.VEJY3_02405 2.52e-211 585.0 COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,1RN44@1236|Gammaproteobacteria,1XTHQ@135623|Vibrionales 135623|Vibrionales H Belongs to the ribF family ribF - 2.7.1.26,2.7.7.2 ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - FAD_syn,Flavokinase k141_29298_30 1116375.VEJY3_02410 0.0 1887.0 COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,1RMTF@1236|Gammaproteobacteria,1XSUS@135623|Vibrionales 135623|Vibrionales J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1,zf-FPG_IleRS k141_29298_31 223926.28805518 7.58e-122 347.0 COG0597@1|root,COG0597@2|Bacteria,1RGV9@1224|Proteobacteria,1S60E@1236|Gammaproteobacteria,1XT9S@135623|Vibrionales 135623|Vibrionales MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins lspA - 3.4.23.36 ko:K03101 ko03060,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_A8 k141_29298_32 672.VV93_v1c06290 4.12e-93 272.0 COG1047@1|root,COG1047@2|Bacteria,1RHD1@1224|Proteobacteria,1S5YP@1236|Gammaproteobacteria,1XWVG@135623|Vibrionales 135623|Vibrionales G COG1047 FKBP-type peptidyl-prolyl cis-trans isomerases 2 fkpB - 5.2.1.8 ko:K03774 - - - - ko00000,ko01000,ko03110 - - - FKBP_C k141_29298_33 1116375.VEJY3_02425 1.81e-223 616.0 COG0761@1|root,COG0761@2|Bacteria,1MU7G@1224|Proteobacteria,1RMN8@1236|Gammaproteobacteria,1XTYD@135623|Vibrionales 135623|Vibrionales IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis ispH - 1.17.7.4 ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05884,R08210 RC01137,RC01487 ko00000,ko00001,ko00002,ko01000 - - - LYTB k141_22281_1 1279017.AQYJ01000024_gene942 2.78e-06 50.8 COG0477@1|root,COG2814@2|Bacteria,1MVSC@1224|Proteobacteria,1S029@1236|Gammaproteobacteria,465C0@72275|Alteromonadaceae 1236|Gammaproteobacteria EGP Major facilitator superfamily - - - - - - - - - - - - MFS_1 k141_22281_2 1279017.AQYJ01000024_gene943 1.92e-74 246.0 COG4264@1|root,COG4264@2|Bacteria,1QUJJ@1224|Proteobacteria,1RQQ0@1236|Gammaproteobacteria,4672K@72275|Alteromonadaceae 1236|Gammaproteobacteria Q IucA / IucC family iucA - 6.3.2.38 ko:K03894 ko00310,ko01120,map00310,map01120 - R10090 RC00064,RC00090 ko00000,ko00001,ko01000 - - - Acetyltransf_8,FhuF,IucA_IucC k141_11664_2 1121938.AUDY01000011_gene593 4.16e-192 540.0 28PXD@1|root,2ZCHC@2|Bacteria,1V1WS@1239|Firmicutes,4HG73@91061|Bacilli 91061|Bacilli S Ecdysteroid kinase - - - - - - - - - - - - APH,EcKinase k141_11664_3 1121938.AUDY01000011_gene594 1.52e-33 125.0 COG3919@1|root,COG3919@2|Bacteria,1TQPN@1239|Firmicutes,4HAB0@91061|Bacilli,3NEMS@45667|Halobacillus 91061|Bacilli S D-ala D-ala ligase C-terminus yxbA - 6.3.1.12 ko:K17810 - - - - ko00000,ko01000 - - - - k141_27299_1 218284.CCDN010000001_gene1396 1.35e-157 449.0 COG2008@1|root,COG2008@2|Bacteria,1TPZI@1239|Firmicutes,4HAM3@91061|Bacilli,1ZD31@1386|Bacillus 91061|Bacilli E Threonine aldolase - - 4.1.2.48 ko:K01620 ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230 - R00751,R06171 RC00312,RC00372 ko00000,ko00001,ko01000 - - - Beta_elim_lyase k141_27299_2 218284.CCDN010000001_gene1395 5.04e-50 172.0 COG1396@1|root,COG1396@2|Bacteria,1U4VN@1239|Firmicutes,4HE98@91061|Bacilli,1ZDJQ@1386|Bacillus 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - ko:K20480 ko02024,map02024 - - - ko00000,ko00001,ko03000 - - - HTH_3,TPR_12,TPR_7,TPR_8 k141_3134_1 379066.GAU_2199 6.91e-36 141.0 COG1629@1|root,COG4771@2|Bacteria,1ZUQM@142182|Gemmatimonadetes 142182|Gemmatimonadetes P Carboxypeptidase regulatory-like domain - - - - - - - - - - - - CarboxypepD_reg k141_9301_1 1274524.BSONL12_04619 2.06e-33 132.0 2EQUX@1|root,33IEQ@2|Bacteria,1W342@1239|Firmicutes 1239|Firmicutes S Phage portal protein, SPP1 Gp6-like - - - - - - - - - - - - Phage_prot_Gp6 k141_35387_1 935836.JAEL01000004_gene2511 5.6e-90 280.0 COG2233@1|root,COG2233@2|Bacteria,1TQ0A@1239|Firmicutes,4HA6X@91061|Bacilli,1ZD5W@1386|Bacillus 91061|Bacilli F Xanthine uracil - - - - - - - - - - - - Xan_ur_permease k141_7955_114 1122176.KB903565_gene3299 7.24e-10 63.2 COG3150@1|root,COG3150@2|Bacteria,4NZAP@976|Bacteroidetes 976|Bacteroidetes S Uncharacterised protein family (UPF0227) - - - ko:K07000 - - - - ko00000 - - - NT5C,UPF0227 k141_31620_6 1453501.JELR01000001_gene3129 4.58e-68 210.0 COG0801@1|root,COG0801@2|Bacteria,1MZH8@1224|Proteobacteria,1S63J@1236|Gammaproteobacteria,467BR@72275|Alteromonadaceae 1236|Gammaproteobacteria H COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase folK GO:0000287,GO:0003674,GO:0003824,GO:0003848,GO:0005488,GO:0016740,GO:0016772,GO:0016778,GO:0043167,GO:0043169,GO:0046872 2.7.6.3 ko:K00950 ko00790,ko01100,map00790,map01100 M00126,M00841 R03503 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - iECDH1ME8569_1439.ECDH1ME8569_0136,iEcDH1_1363.EcDH1_3460,iJN746.PP_4698,iSBO_1134.SBO_0131 HPPK k141_31620_7 1279017.AQYJ01000024_gene875 8.07e-259 717.0 COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,1RMBG@1236|Gammaproteobacteria,464KY@72275|Alteromonadaceae 1236|Gammaproteobacteria H Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control pcnB GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004652,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006276,GO:0006378,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0031123,GO:0031124,GO:0034641,GO:0043170,GO:0043412,GO:0043631,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070566,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 2.7.7.19 ko:K00970 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - PolyA_pol,PolyA_pol_RNAbd,PolyA_pol_arg_C k141_31620_8 1453501.JELR01000001_gene3127 5.09e-290 797.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,4647X@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains cbrB - - ko:K10943 ko02020,ko05111,map02020,map05111 M00515 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat k141_31620_9 1279017.AQYJ01000024_gene878 0.0 1393.0 COG0591@1|root,COG4191@1|root,COG0591@2|Bacteria,COG4191@2|Bacteria,1QTSW@1224|Proteobacteria,1T1G2@1236|Gammaproteobacteria,4643M@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0591 Na proline symporter cbrA - - - - - - - - - - - HATPase_c,HisKA,PAS k141_33072_1 1423321.AS29_21250 7.7e-82 251.0 COG1210@1|root,COG1210@2|Bacteria,1TQ24@1239|Firmicutes,4HATY@91061|Bacilli,1ZASX@1386|Bacillus 91061|Bacilli M UTP-glucose-1-phosphate uridylyltransferase - - 2.7.7.9 ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 M00129,M00361,M00362,M00549 R00289 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase k141_17627_1 35841.BT1A1_2117 7.83e-16 69.7 2BYGW@1|root,33J7Z@2|Bacteria,1W1WC@1239|Firmicutes,4HSU3@91061|Bacilli,1ZK1V@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_17627_2 1294265.JCM21738_2 3.38e-54 175.0 COG1073@1|root,COG1073@2|Bacteria,1TQYU@1239|Firmicutes,4HC4H@91061|Bacilli,1ZBDV@1386|Bacillus 91061|Bacilli S COG1073 Hydrolases of the alpha beta superfamily yqkD - - ko:K06889 - - - - ko00000 - - - Hydrolase_4 k141_20189_2 398511.BpOF4_09290 3.7e-23 89.4 COG1826@1|root,COG1826@2|Bacteria,1VFP2@1239|Firmicutes,4HNM7@91061|Bacilli,1ZIUG@1386|Bacillus 91061|Bacilli U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system tatA - - ko:K03116 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - MttA_Hcf106 k141_28197_1 95619.PM1_0208530 2.25e-52 175.0 COG2818@1|root,COG2818@2|Bacteria,1R3WB@1224|Proteobacteria,1RSAH@1236|Gammaproteobacteria 1236|Gammaproteobacteria L 3-Methyladenine DNA glycosylase IV02_03670 - - - - - - - - - - - Adenine_glyco k141_28197_2 1005048.CFU_3460 3.36e-98 298.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2VIX2@28216|Betaproteobacteria,47673@75682|Oxalobacteraceae 28216|Betaproteobacteria I Thiolase, C-terminal domain - - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N k141_21142_1 1294265.JCM21738_5159 8.01e-38 129.0 2CBNY@1|root,330BE@2|Bacteria,1VGPH@1239|Firmicutes,4HNX7@91061|Bacilli,1ZH6P@1386|Bacillus 91061|Bacilli S Sporulation protein YtrH ytrH - - - - - - - - - - - Spore_YtrH k141_21142_2 1294265.JCM21738_5158 1.25e-131 404.0 COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,4H9T3@91061|Bacilli,1ZCIC@1386|Bacillus 91061|Bacilli L DNA polymerase dnaE - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon k141_13071_1 1453501.JELR01000001_gene3096 2.58e-110 328.0 COG0773@1|root,COG0773@2|Bacteria,1MUC5@1224|Proteobacteria,1RMMT@1236|Gammaproteobacteria,465PV@72275|Alteromonadaceae 1236|Gammaproteobacteria M Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate mpl - 6.3.2.45 ko:K02558 - - - - ko00000,ko01000 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M k141_29622_1 218284.CCDN010000004_gene3084 2.47e-115 336.0 COG0564@1|root,COG0564@2|Bacteria,1TSM6@1239|Firmicutes,4HA7M@91061|Bacilli,1ZDMG@1386|Bacillus 91061|Bacilli J Responsible for synthesis of pseudouridine from uracil rluA GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23,5.4.99.28,5.4.99.29 ko:K06177,ko:K06180 - - - - ko00000,ko01000,ko03009,ko03016 - - - PseudoU_synth_2 k141_37757_1 1385514.N782_00375 1.06e-123 369.0 COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,4HADT@91061|Bacilli,2YBFQ@289201|Pontibacillus 91061|Bacilli KT Sigma-54 interaction domain - - - - - - - - - - - - HTH_8,PAS,PAS_4,PAS_9,Sigma54_activat k141_17628_1 218284.CCDN010000002_gene2183 1.88e-102 302.0 COG1503@1|root,COG1503@2|Bacteria,1TT2U@1239|Firmicutes,4HC2I@91061|Bacilli,1ZECE@1386|Bacillus 91061|Bacilli J translation release factor activity - - - - - - - - - - - - - k141_24918_1 218284.CCDN010000003_gene2969 3.08e-48 160.0 COG4123@1|root,COG4123@2|Bacteria,1TQ25@1239|Firmicutes,4HA8W@91061|Bacilli,1ZCBX@1386|Bacillus 91061|Bacilli S Conserved hypothetical protein 95 yabB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.223 ko:K07461,ko:K15460 - - - - ko00000,ko01000,ko03016 - - - GIY-YIG,MTS k141_24918_2 218284.CCDN010000003_gene2970 9.17e-167 471.0 COG0313@1|root,COG0313@2|Bacteria,1TP6U@1239|Firmicutes,4HAH8@91061|Bacilli,1ZBN1@1386|Bacillus 91061|Bacilli H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA rsmI GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 2.1.1.198 ko:K07056 - - - - ko00000,ko01000,ko03009 - - - TP_methylase k141_24918_4 218284.CCDN010000003_gene2972 2.44e-89 280.0 COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1TPA1@1239|Firmicutes,4H9VC@91061|Bacilli,1ZASP@1386|Bacillus 91061|Bacilli J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation metG GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1g,tRNA_bind k141_31621_1 1196031.ALEG01000059_gene5509 3.97e-67 212.0 29HQ2@1|root,304MB@2|Bacteria,1V21Z@1239|Firmicutes,4HG8B@91061|Bacilli,1ZC8S@1386|Bacillus 91061|Bacilli S Spore gernimation protein gerD - - ko:K06294 - - - - ko00000 - - - - k141_21143_1 1453501.JELR01000001_gene3198 2.76e-46 169.0 COG3240@1|root,COG3240@2|Bacteria,1RCCU@1224|Proteobacteria,1S2GX@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Phospholipase lecithinase hemolysin estA GO:0003674,GO:0003824,GO:0016289,GO:0016290,GO:0016787,GO:0016788,GO:0016790,GO:0047617,GO:0052689 - ko:K12686 - - - - ko00000,ko02000,ko02044 1.B.12.8 - - Autotransporter,Lipase_GDSL k141_2121_1 218284.CCDN010000009_gene4317 6.95e-112 326.0 COG2861@1|root,COG2861@2|Bacteria,1V413@1239|Firmicutes,4HCXZ@91061|Bacilli,1ZEQY@1386|Bacillus 91061|Bacilli S protein conserved in bacteria yibQ - - ko:K09798 - - - - ko00000 - - - Polysacc_deac_2 k141_15189_1 218284.CCDN010000006_gene3505 8.49e-52 165.0 COG0526@1|root,COG0526@2|Bacteria,1VEVR@1239|Firmicutes,4HNM9@91061|Bacilli,1ZIVX@1386|Bacillus 91061|Bacilli CO Thioredoxin yusE GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - - - - - - - - - - Thioredoxin k141_17629_1 218284.CCDN010000007_gene3906 1.14e-161 457.0 COG0451@1|root,COG0451@2|Bacteria,1TSUN@1239|Firmicutes,4HA3D@91061|Bacilli,1ZAUE@1386|Bacillus 91061|Bacilli GM GDP-mannose 4,6 dehydratase - - - - - - - - - - - - Epimerase k141_13072_1 1279017.AQYJ01000029_gene3747 4.99e-132 397.0 COG3387@1|root,COG3387@2|Bacteria,1MW9J@1224|Proteobacteria,1T2G2@1236|Gammaproteobacteria,465X7@72275|Alteromonadaceae 1236|Gammaproteobacteria G PFAM Glycoside hydrolase 15-related - - - - - - - - - - - - F5_F8_type_C,GDE_C k141_10573_1 223926.28805949 1.57e-242 669.0 COG4006@1|root,COG4006@2|Bacteria,1RFA6@1224|Proteobacteria,1S6RM@1236|Gammaproteobacteria,1XU5U@135623|Vibrionales 135623|Vibrionales S Domain of unknown function (DUF1887) VV2376 - - - - - - - - - - - DUF1887 k141_10573_2 1219076.N646_0029 5.63e-174 486.0 COG2820@1|root,COG2820@2|Bacteria,1P0EC@1224|Proteobacteria,1RN3N@1236|Gammaproteobacteria,1XSZE@135623|Vibrionales 135623|Vibrionales F Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis udp - 2.4.2.3 ko:K00757 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R01876,R02484,R08229 RC00063 ko00000,ko00001,ko01000 - - - PNP_UDP_1 k141_10573_3 223926.28805946 0.0 1183.0 COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,1XSWI@135623|Vibrionales 135623|Vibrionales P cation transport ATPase zntA - 3.6.3.3,3.6.3.5 ko:K01534 - - - - ko00000,ko01000 3.A.3.6 - - E1-E2_ATPase,HMA,Hydrolase k141_10573_4 223926.28805945 6.92e-90 264.0 COG0517@1|root,COG0517@2|Bacteria,1N2XI@1224|Proteobacteria,1SA5K@1236|Gammaproteobacteria,1XXA2@135623|Vibrionales 135623|Vibrionales S COG0517 FOG CBS domain - - - - - - - - - - - - CBS k141_10573_5 1116375.VEJY3_04435 1.1e-42 152.0 COG2509@1|root,COG2509@2|Bacteria,1MV6P@1224|Proteobacteria,1RPTW@1236|Gammaproteobacteria,1XVBT@135623|Vibrionales 135623|Vibrionales S FAD-dependent dehydrogenases - - - ko:K07137 - - - - ko00000 - - - Amino_oxidase,FAD_binding_3 k141_4560_1 218284.CCDN010000002_gene2760 4.66e-98 292.0 COG0673@1|root,COG0673@2|Bacteria,1UZRV@1239|Firmicutes,4HEWB@91061|Bacilli,1ZE5A@1386|Bacillus 91061|Bacilli S dehydrogenases and related proteins ysjB - - ko:K03810 - - - - ko00000 - - - GFO_IDH_MocA k141_21144_1 42565.FP66_07450 1.54e-17 80.9 COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,1RMU8@1236|Gammaproteobacteria,1XI27@135619|Oceanospirillales 135619|Oceanospirillales G phosphomannomutase algC - 5.4.2.2,5.4.2.8 ko:K15778 ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00114 R00959,R01057,R01818,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV k141_21144_2 42565.FP66_07445 8.94e-101 292.0 COG0756@1|root,COG0756@2|Bacteria,1RA7P@1224|Proteobacteria,1S233@1236|Gammaproteobacteria,1XJP4@135619|Oceanospirillales 135619|Oceanospirillales F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA dut - 3.6.1.23 ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00053 R02100,R11896 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 - - - dUTPase k141_2122_1 1487923.DP73_21280 2.57e-124 366.0 COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,264M9@186807|Peptococcaceae 186801|Clostridia P Transporter associated domain - - - ko:K03699 - - - - ko00000,ko02042 - - - CBS,CorC_HlyC,DUF21 k141_31623_1 1042377.AFPJ01000043_gene852 5.07e-37 130.0 2DBQ1@1|root,2ZABN@2|Bacteria,1R83J@1224|Proteobacteria,1T169@1236|Gammaproteobacteria,46BUW@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_31623_2 566466.NOR53_1927 2.71e-26 107.0 COG3214@1|root,COG3214@2|Bacteria,1N40B@1224|Proteobacteria,1RPYB@1236|Gammaproteobacteria,1J5SU@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria ycaQ - - ko:K09927 - - - - ko00000 - - - HTH_42 k141_7984_2 1122212.AULO01000010_gene109 2.43e-139 417.0 COG0415@1|root,COG0415@2|Bacteria,1MV9Y@1224|Proteobacteria,1RNGJ@1236|Gammaproteobacteria,1XIX5@135619|Oceanospirillales 135619|Oceanospirillales L Belongs to the DNA photolyase family phrB - 4.1.99.3 ko:K01669 - - - - ko00000,ko01000,ko03400 - - - DNA_photolyase,FAD_binding_7 k141_21145_1 1403313.AXBR01000006_gene43 2.52e-45 150.0 COG3296@1|root,COG3296@2|Bacteria,1VJNI@1239|Firmicutes,4HKFS@91061|Bacilli,1ZQSE@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF4870) - - - ko:K09940 - - - - ko00000 - - - DUF4870 k141_33076_1 218284.CCDN010000008_gene4040 1.24e-111 332.0 COG1228@1|root,COG1228@2|Bacteria,1TP2J@1239|Firmicutes,4HAVY@91061|Bacilli,1ZDE5@1386|Bacillus 91061|Bacilli Q Imidazolone-5-propionate hydrolase hutI - 3.5.2.7 ko:K01468 ko00340,ko01100,map00340,map01100 M00045 R02288 RC00683 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU39370 Amidohydro_1,Amidohydro_3 k141_20193_1 406124.ACPC01000042_gene2220 9.37e-33 119.0 COG2197@1|root,COG2197@2|Bacteria,1TRXG@1239|Firmicutes,4HCCV@91061|Bacilli,1ZDBY@1386|Bacillus 91061|Bacilli K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain yhcZ - - ko:K02479 - - - - ko00000,ko02022 - - - GerE,Response_reg k141_20193_2 218284.CCDN010000004_gene3092 1.2e-64 208.0 COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,1TR88@1239|Firmicutes,4HBF3@91061|Bacilli,1ZCMJ@1386|Bacillus 91061|Bacilli T Histidine kinase yhcY - 2.7.13.3 ko:K02480 - - - - ko00000,ko01000,ko01001,ko02022 - - - GAF_2,HATPase_c,HisKA_3 k141_10575_1 1385511.N783_00045 2.8e-91 275.0 COG2145@1|root,COG2145@2|Bacteria,1V1R6@1239|Firmicutes,4HFTJ@91061|Bacilli,2Y8UB@289201|Pontibacillus 91061|Bacilli H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ) thiM GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008972,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.50 ko:K00878 ko00730,ko01100,map00730,map01100 M00127 R04448 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - HK k141_24921_1 218284.CCDN010000001_gene1391 3e-113 329.0 COG4814@1|root,COG4814@2|Bacteria,1V910@1239|Firmicutes,4HF90@91061|Bacilli,1ZHBI@1386|Bacillus 91061|Bacilli S Alpha/beta hydrolase of unknown function (DUF915) - - - - - - - - - - - - DUF915 k141_20194_1 1453501.JELR01000002_gene849 8.57e-122 371.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MV8W@1224|Proteobacteria,1RMQA@1236|Gammaproteobacteria,46619@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec k141_2500_2 218284.CCDN010000007_gene3999 1.31e-84 263.0 COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,4HAMZ@91061|Bacilli,1ZB13@1386|Bacillus 91061|Bacilli C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit atpA - 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - iSB619.SA_RS10975 ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N k141_6074_1 1042377.AFPJ01000007_gene1878 4.85e-169 476.0 COG2866@1|root,COG2866@2|Bacteria,1MYRD@1224|Proteobacteria,1T1MH@1236|Gammaproteobacteria,46D94@72275|Alteromonadaceae 1236|Gammaproteobacteria E Succinylglutamate desuccinylase / Aspartoacylase family XCC2022 - - - - - - - - - - - AstE_AspA,DUF2817,Peptidase_M14 k141_21547_1 1042377.AFPJ01000004_gene341 1.82e-114 335.0 COG0837@1|root,COG0837@2|Bacteria,1MVFI@1224|Proteobacteria,1RNUY@1236|Gammaproteobacteria,464W6@72275|Alteromonadaceae 1236|Gammaproteobacteria F Belongs to the bacterial glucokinase family glk - 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Glucokinase k141_23856_1 1294265.JCM21738_4235 1.1e-129 377.0 COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,4HF1R@91061|Bacilli,1ZDU3@1386|Bacillus 91061|Bacilli M Belongs to the peptidase S11 family - - 3.4.16.4 ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - PBP5_C,Peptidase_S11 k141_147_2 1453501.JELR01000002_gene537 3.02e-14 71.2 COG3577@1|root,COG3577@2|Bacteria,1N2PE@1224|Proteobacteria,1S66F@1236|Gammaproteobacteria,467QR@72275|Alteromonadaceae 1236|Gammaproteobacteria S gag-polyprotein putative aspartyl protease - - - ko:K06985 ko04112,map04112 - - - ko00000,ko00001 - - - gag-asp_proteas k141_22712_1 1246484.D479_03743 3.27e-75 241.0 COG0827@1|root,COG0827@2|Bacteria,1U5AT@1239|Firmicutes,4HS35@91061|Bacilli,3NFY2@45667|Halobacillus 91061|Bacilli L Eco57I restriction-modification methylase - - - - - - - - - - - - N6_Mtase k141_25048_1 1307436.PBF_00505 1.4e-182 513.0 COG1840@1|root,COG1840@2|Bacteria,1TSKP@1239|Firmicutes,4HBH2@91061|Bacilli,1ZDRE@1386|Bacillus 91061|Bacilli P Bacterial extracellular solute-binding protein - - - ko:K02012 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - SBP_bac_6,SBP_bac_8 k141_28670_1 218284.CCDN010000007_gene3984 4.37e-70 215.0 COG1971@1|root,COG1971@2|Bacteria,1V4QK@1239|Firmicutes,4HH7C@91061|Bacilli,1ZFK0@1386|Bacillus 91061|Bacilli P Probably functions as a manganese efflux pump mntP - - - - - - - - - - - Mntp k141_28670_2 218284.CCDN010000007_gene3983 1.95e-120 352.0 COG0009@1|root,COG0009@2|Bacteria,1TP1I@1239|Firmicutes,4HA7W@91061|Bacilli,1ZB2V@1386|Bacillus 91061|Bacilli J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine ywlC GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87 ko:K07566 - - R10463 RC00745 ko00000,ko01000,ko03009,ko03016 - - - SUA5,Sua5_yciO_yrdC k141_27417_1 1131730.BAVI_01914 3.59e-59 195.0 COG3180@1|root,COG3180@2|Bacteria,1UVXN@1239|Firmicutes,4HDRW@91061|Bacilli,1ZDNB@1386|Bacillus 91061|Bacilli S membrane - - - ko:K07120 - - - - ko00000 - - - AbrB k141_35748_1 1294265.JCM21738_3802 1.72e-76 229.0 2BW8R@1|root,32SRF@2|Bacteria,1VD0C@1239|Firmicutes,4HMPU@91061|Bacilli,1ZNPE@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_14399_1 796606.BMMGA3_07645 3.19e-201 583.0 COG3973@1|root,COG3973@2|Bacteria,1TP39@1239|Firmicutes,4H9Y5@91061|Bacilli,1ZAWP@1386|Bacillus 91061|Bacilli L DNA helicase uvrD - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_19,UvrD-helicase,UvrD_C,UvrD_C_2 k141_11978_1 545693.BMQ_1445 7.36e-128 375.0 COG1653@1|root,COG1653@2|Bacteria,1TQJE@1239|Firmicutes,4HCS3@91061|Bacilli,1ZDT6@1386|Bacillus 91061|Bacilli G Bacterial extracellular solute-binding protein - - - ko:K10117 ko02010,map02010 M00196 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.28 - - SBP_bac_1,SBP_bac_8 k141_26299_1 218284.CCDN010000004_gene3086 3.4e-62 193.0 COG0526@1|root,COG0526@2|Bacteria,1V3YC@1239|Firmicutes,4HJ8N@91061|Bacilli,1ZH2W@1386|Bacillus 91061|Bacilli CO Thioredoxin bdbA - - - - - - - - - - - Thioredoxin k141_34597_1 218284.CCDN010000001_gene39 8.7e-07 49.3 COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,4H9RW@91061|Bacilli,1ZCUF@1386|Bacillus 91061|Bacilli G Belongs to the ribulose-phosphate 3-epimerase family rpe GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 - - - Ribul_P_3_epim k141_34597_2 218284.CCDN010000001_gene38 3.41e-103 303.0 COG1564@1|root,COG1564@2|Bacteria,1VA0W@1239|Firmicutes,4HHS1@91061|Bacilli,1ZD4A@1386|Bacillus 91061|Bacilli H thiamine pyrophosphokinase thiN - 2.7.6.2 ko:K00949 ko00730,ko01100,map00730,map01100 - R00619 RC00002,RC00017 ko00000,ko00001,ko01000 - - - TPK_B1_binding,TPK_catalytic k141_6075_1 218284.CCDN010000001_gene53 1.34e-151 442.0 COG1293@1|root,COG1293@2|Bacteria,1TQ8A@1239|Firmicutes,4H9UF@91061|Bacilli,1ZBGD@1386|Bacillus 91061|Bacilli K RNA-binding protein homologous to eukaryotic snRNP FbpA - - - - - - - - - - - DUF814,FbpA k141_13222_1 1279017.AQYJ01000023_gene3160 3.12e-110 338.0 COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,1RPJB@1236|Gammaproteobacteria,466BN@72275|Alteromonadaceae 1236|Gammaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoN GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 ko:K00343 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_M k141_13222_2 1279017.AQYJ01000023_gene3161 2.02e-13 72.8 COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,1RNI4@1236|Gammaproteobacteria,4664Q@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1008 NADH ubiquinone oxidoreductase subunit 4 (chain M) nuoM - 1.6.5.3 ko:K00342 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_M k141_4875_1 218284.CCDN010000005_gene3361 5.81e-36 133.0 COG0168@1|root,COG0168@2|Bacteria,1TQ4S@1239|Firmicutes,4H9ME@91061|Bacilli,1ZD2H@1386|Bacillus 91061|Bacilli P COG0168 Trk-type K transport systems, membrane components ktrD - - - - - - - - - - - TrkH k141_29809_1 1219072.VHA01S_008_00750 1.44e-142 411.0 COG3203@1|root,COG3203@2|Bacteria,1QTIE@1224|Proteobacteria,1SWVJ@1236|Gammaproteobacteria,1XSH5@135623|Vibrionales 135623|Vibrionales M COG3203 Outer membrane protein (porin) - - - - - - - - - - - - Porin_4 k141_29809_2 1219072.VHA01S_008_00740 3.17e-78 233.0 COG0251@1|root,COG0251@2|Bacteria,1MZ3J@1224|Proteobacteria,1S5XS@1236|Gammaproteobacteria,1XY48@135623|Vibrionales 135623|Vibrionales J Endoribonuclease L-PSP - - 3.5.99.10 ko:K09022 - - R11098,R11099 RC03275,RC03354 ko00000,ko01000 - - - Ribonuc_L-PSP k141_29809_3 1348635.BBJY01000020_gene2767 1.34e-181 513.0 COG0814@1|root,COG0814@2|Bacteria,1MWGI@1224|Proteobacteria,1RMME@1236|Gammaproteobacteria,1XTGR@135623|Vibrionales 135623|Vibrionales U COG0814 Amino acid permeases mtr - - ko:K03835 - - - - ko00000,ko02000 2.A.42.1.2 - - Trp_Tyr_perm k141_15599_1 218284.CCDN010000002_gene2545 2.26e-109 326.0 COG0582@1|root,COG0582@2|Bacteria,1UIWX@1239|Firmicutes,4ISV4@91061|Bacilli,1ZFA3@1386|Bacillus 91061|Bacilli L Putative transposase - - - - - - - - - - - - Y2_Tnp,Zn_Tnp_IS91 k141_31035_2 218284.CCDN010000004_gene3073 9.55e-120 351.0 COG1609@1|root,COG1609@2|Bacteria,1TQSQ@1239|Firmicutes,4HBNR@91061|Bacilli,1ZC0J@1386|Bacillus 91061|Bacilli K Transcriptional regulator ykvZ - - - - - - - - - - - LacI,Peripla_BP_1,Peripla_BP_3 k141_28672_1 1122139.KB907862_gene551 1.96e-100 299.0 COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,1RNJ1@1236|Gammaproteobacteria,1XIPB@135619|Oceanospirillales 135619|Oceanospirillales P PFAM binding-protein-dependent transport systems inner membrane component - - - ko:K02033 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 k141_2502_1 666686.B1NLA3E_20385 4.16e-120 345.0 COG2009@1|root,COG2009@2|Bacteria,1TQUI@1239|Firmicutes,4HBX0@91061|Bacilli,1ZMGR@1386|Bacillus 91061|Bacilli C Succinate dehydrogenase/Fumarate reductase transmembrane subunit sdhC - - ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002 - - - Sdh_cyt k141_6076_1 218284.CCDN010000001_gene1552 1.03e-103 320.0 COG0768@1|root,COG0768@2|Bacteria,1TQHY@1239|Firmicutes,4HAFX@91061|Bacilli,1ZBJM@1386|Bacillus 91061|Bacilli M penicillin-binding protein pbpH - - ko:K21465 ko00550,map00550 - - - ko00000,ko00001,ko01011 - - - PBP_dimer,Transpeptidase k141_9607_1 1279017.AQYJ01000025_gene469 2.94e-102 306.0 COG0409@1|root,COG0409@2|Bacteria,1MU1F@1224|Proteobacteria,1RRTQ@1236|Gammaproteobacteria,466NH@72275|Alteromonadaceae 1236|Gammaproteobacteria O Belongs to the HypD family hypD - - ko:K04654 - - - - ko00000 - - - HypD k141_9607_2 518766.Rmar_2594 5.91e-28 103.0 COG0298@1|root,COG0298@2|Bacteria,4NX9T@976|Bacteroidetes 976|Bacteroidetes O PFAM hydrogenase expression formation protein (HUPF HYPC) - - - ko:K04653 - - - - ko00000 - - - HupF_HypC k141_9607_3 1279017.AQYJ01000025_gene471 1.09e-50 180.0 COG0068@1|root,COG0068@2|Bacteria,1MVP8@1224|Proteobacteria,1RP08@1236|Gammaproteobacteria,4642Z@72275|Alteromonadaceae 1236|Gammaproteobacteria O Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide hypF GO:0003674,GO:0003824,GO:0005488,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0010467,GO:0016740,GO:0016741,GO:0016743,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046872,GO:0046914,GO:0046944,GO:0051604,GO:0071704,GO:1901564 - ko:K04656 - - - - ko00000 - - - Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF k141_3696_1 1116375.VEJY3_21656 1.16e-181 507.0 COG0656@1|root,COG0656@2|Bacteria,1MWFS@1224|Proteobacteria,1RRAV@1236|Gammaproteobacteria,1XYG2@135623|Vibrionales 135623|Vibrionales S Aldo/keto reductase family - - - - - - - - - - - - Aldo_ket_red k141_7250_1 1280001.BAOA01000011_gene4246 7.73e-167 477.0 COG0114@1|root,COG0114@2|Bacteria,1MUQI@1224|Proteobacteria,1RNUS@1236|Gammaproteobacteria,1XVJG@135623|Vibrionales 135623|Vibrionales C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate fumC - 4.2.1.2 ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 M00009,M00011,M00173,M00376 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - - FumaraseC_C,Lyase_1 k141_7250_2 1116375.VEJY3_14590 4.12e-108 311.0 2DDDN@1|root,32U19@2|Bacteria,1N1UD@1224|Proteobacteria,1SAT8@1236|Gammaproteobacteria,1XUWT@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_7250_3 1116375.VEJY3_14585 1.63e-176 505.0 COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,1RN0R@1236|Gammaproteobacteria,1XSJY@135623|Vibrionales 135623|Vibrionales S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family actP - - ko:K14393 - - - - ko00000,ko02000 2.A.21.7 - - SSF k141_36946_1 388399.SSE37_10849 3.34e-25 101.0 COG4961@1|root,COG4961@2|Bacteria,1MZBW@1224|Proteobacteria,2UCBG@28211|Alphaproteobacteria 28211|Alphaproteobacteria U Flp pilus assembly protein TadG - - - - - - - - - - - - TadE k141_36946_2 1123237.Salmuc_04843 8.34e-10 58.9 COG4655@1|root,COG4961@1|root,COG4655@2|Bacteria,COG4961@2|Bacteria,1MWXU@1224|Proteobacteria,2TRQP@28211|Alphaproteobacteria 28211|Alphaproteobacteria U Flp pilus assembly protein TadG - - - - - - - - - - - - Tad k141_31064_1 218284.CCDN010000002_gene2946 2.16e-158 448.0 COG4586@1|root,COG4586@2|Bacteria,1TP1N@1239|Firmicutes,4H9NR@91061|Bacilli,1ZBGB@1386|Bacillus 91061|Bacilli S transport system, ATPase component drrA1 - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_23870_1 218284.CCDN010000001_gene102 8.46e-73 226.0 COG1024@1|root,COG1024@2|Bacteria,1UZHP@1239|Firmicutes,4HEEK@91061|Bacilli,1ZB0V@1386|Bacillus 91061|Bacilli I COG1024 Enoyl-CoA hydratase carnithine racemase - - - - - - - - - - - - ECH_1 k141_176_1 1123371.ATXH01000014_gene1607 7.32e-27 113.0 COG0013@1|root,COG0013@2|Bacteria,2GH36@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain alaS - 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DHHA1,tRNA-synt_2c,tRNA_SAD k141_9623_1 218284.CCDN010000006_gene3661 1.98e-35 130.0 COG1932@1|root,COG1932@2|Bacteria,1TP6Y@1239|Firmicutes,4HATT@91061|Bacilli,1ZB9N@1386|Bacillus 91061|Bacilli E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine serC GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 M00020,M00124 R04173,R05085 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_5 k141_26311_1 1042377.AFPJ01000024_gene709 6.59e-13 68.2 COG0651@1|root,COG0651@2|Bacteria,1MV6V@1224|Proteobacteria,1RQK5@1236|Gammaproteobacteria,464XB@72275|Alteromonadaceae 1236|Gammaproteobacteria CP Proton-conducting membrane transporter - - - ko:K05568 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - Proton_antipo_M k141_177_2 1294265.JCM21738_2444 3.45e-15 73.6 COG2208@1|root,COG2208@2|Bacteria,1TQY5@1239|Firmicutes,4HAF6@91061|Bacilli,1ZBIB@1386|Bacillus 91061|Bacilli KT phosphatase rsbU - 3.1.3.3 ko:K07315 - - - - ko00000,ko01000,ko03021 - - - RsbU_N,SpoIIE k141_28694_1 1453501.JELR01000002_gene1244 3.72e-30 112.0 2EB97@1|root,3359Q@2|Bacteria,1NBYB@1224|Proteobacteria,1SDC9@1236|Gammaproteobacteria,468XQ@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_16754_1 1117314.PCIT_19754 1.22e-61 213.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,2Q1ZW@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K18138 ko01501,ko01503,map01501,map01503 M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2 - - ACR_tran k141_31065_1 218284.CCDN010000001_gene190 3.57e-10 60.1 COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,4HA3G@91061|Bacilli,1ZAVY@1386|Bacillus 91061|Bacilli T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,PAS_4,PAS_9 k141_10795_1 218284.CCDN010000004_gene3138 7.19e-104 307.0 COG0834@1|root,COG0834@2|Bacteria,1TR13@1239|Firmicutes,4HBRP@91061|Bacilli,1ZCH3@1386|Bacillus 91061|Bacilli ET Belongs to the bacterial solute-binding protein 3 family tcyA - - ko:K02424 ko02010,map02010 M00234 - - ko00000,ko00001,ko00002,ko02000,ko02035 3.A.1.3.10,3.A.1.3.14 - - SBP_bac_3 k141_178_1 501479.ACNW01000113_gene4032 1.48e-117 342.0 COG3396@1|root,COG3396@2|Bacteria,1MVQ7@1224|Proteobacteria,2TTC4@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Phenylacetate-CoA oxygenase paaA - 1.14.13.149 ko:K02609 ko00360,ko01120,map00360,map01120 - R09838 RC02690 ko00000,ko00001,ko01000 - - - PaaA_PaaC k141_178_2 501479.ACNW01000113_gene4033 8.38e-24 91.3 COG3460@1|root,COG3460@2|Bacteria,1RHM5@1224|Proteobacteria,2U9HF@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q phenylacetic acid degradation paaB - - ko:K02610 ko00360,ko01120,map00360,map01120 - R09838 RC02690 ko00000,ko00001 - - - PaaB k141_2525_1 1453501.JELR01000002_gene1229 2.03e-91 276.0 COG2177@1|root,COG2177@2|Bacteria,1MU65@1224|Proteobacteria,1RYBV@1236|Gammaproteobacteria,464N0@72275|Alteromonadaceae 1236|Gammaproteobacteria D Part of the ABC transporter FtsEX involved in cellular division ftsX GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0009274,GO:0009276,GO:0009987,GO:0016020,GO:0016021,GO:0030312,GO:0030313,GO:0031224,GO:0031975,GO:0032153,GO:0044425,GO:0044464,GO:0051301,GO:0071944 - ko:K09811 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - FtsX k141_3717_1 218284.CCDN010000008_gene4147 1.34e-138 402.0 COG4948@1|root,COG4948@2|Bacteria,1TQMS@1239|Firmicutes,4HBMX@91061|Bacilli,1ZBMS@1386|Bacillus 91061|Bacilli H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) menC GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.2.1.113 ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R04031 RC01053 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU30780 MR_MLE_C,MR_MLE_N k141_6111_1 42565.FP66_10190 9.95e-26 104.0 COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,1RMTF@1236|Gammaproteobacteria,1XHN6@135619|Oceanospirillales 135619|Oceanospirillales J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS - 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1,zf-FPG_IleRS k141_6111_2 42565.FP66_10195 1.91e-108 313.0 COG0597@1|root,COG0597@2|Bacteria,1RGV9@1224|Proteobacteria,1S60E@1236|Gammaproteobacteria,1XK4C@135619|Oceanospirillales 135619|Oceanospirillales MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins lspA - 3.4.23.36 ko:K03101 ko03060,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_A8 k141_9625_1 218284.CCDN010000002_gene2676 2.1e-89 266.0 COG1309@1|root,COG1309@2|Bacteria,1V7BI@1239|Firmicutes,4HJ8S@91061|Bacilli,1ZFUZ@1386|Bacillus 91061|Bacilli K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_C_8,TetR_N k141_28696_1 998674.ATTE01000001_gene782 2.72e-35 129.0 COG0583@1|root,COG0583@2|Bacteria,1NQFK@1224|Proteobacteria,1RP6V@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator, lysr family - - - - - - - - - - - - HTH_1,LysR_substrate k141_28696_2 42565.FP66_08775 6.17e-05 43.9 COG1902@1|root,COG1902@2|Bacteria,1MVIX@1224|Proteobacteria,1RMFI@1236|Gammaproteobacteria,1XHKD@135619|Oceanospirillales 135619|Oceanospirillales C NADH:flavin oxidoreductase / NADH oxidase family - - - ko:K10680 ko00633,ko01120,map00633,map01120 - R08014,R08017,R08042 RC00250 ko00000,ko00001,ko01000 - - - Oxidored_FMN k141_31066_1 218284.CCDN010000007_gene4015 5.57e-56 185.0 COG0739@1|root,COG0739@2|Bacteria,1V7CU@1239|Firmicutes,4HCZJ@91061|Bacilli,1ZC61@1386|Bacillus 91061|Bacilli M COG0739 Membrane proteins related to metalloendopeptidases spoIIQ GO:0005575,GO:0005623,GO:0042601,GO:0042763,GO:0044464 - ko:K06386 - - - - ko00000 1.A.34.1.1 - - Peptidase_M23 k141_7251_1 1340434.AXVA01000029_gene80 1.12e-05 46.6 COG0313@1|root,COG0313@2|Bacteria,1TP6U@1239|Firmicutes,4HAH8@91061|Bacilli,1ZBN1@1386|Bacillus 91061|Bacilli H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA rsmI GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 2.1.1.198 ko:K07056 - - - - ko00000,ko01000,ko03009 - - - TP_methylase k141_7251_2 1294265.JCM21738_4873 5.03e-60 185.0 COG2002@1|root,COG2002@2|Bacteria,1VA3H@1239|Firmicutes,4HKCH@91061|Bacilli,1ZH0F@1386|Bacillus 91061|Bacilli K COG2002 Regulators of stationary sporulation gene expression abrB GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0042802,GO:0043937,GO:0050789,GO:0050793,GO:0065007 - ko:K06284 - - - - ko00000,ko03000 - - - MazE_antitoxin k141_4879_1 1121377.KB906402_gene3330 6.34e-37 135.0 COG1609@1|root,COG1609@2|Bacteria,1WJSG@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus K PFAM Bacterial regulatory proteins, lacI family - - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 k141_21571_1 1385513.N780_15385 6.09e-31 111.0 COG3125@1|root,COG3125@2|Bacteria,1VFT1@1239|Firmicutes,4HQ12@91061|Bacilli,2YAVU@289201|Pontibacillus 91061|Bacilli C quinol oxidase subunit qoxD GO:0003674,GO:0003824,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016679,GO:0016682,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.10.3.12 ko:K02829 ko00190,ko01100,map00190,map01100 M00416 R09492 RC00819 ko00000,ko00001,ko00002,ko01000 - - - COX4_pro k141_21571_2 240302.BN982_02423 1.16e-56 180.0 COG1845@1|root,COG1845@2|Bacteria,1TQJ1@1239|Firmicutes,4HCWH@91061|Bacilli,3NE5V@45667|Halobacillus 91061|Bacilli C Cytochrome c oxidase subunit III qoxC - 1.10.3.12 ko:K02828 ko00190,ko01100,map00190,map01100 M00416 R09492 RC00819 ko00000,ko00001,ko00002,ko01000 - - - COX3 k141_14415_1 218284.CCDN010000001_gene566 9.02e-99 294.0 COG0451@1|root,COG0451@2|Bacteria,1VP6I@1239|Firmicutes,4HAN7@91061|Bacilli,1ZQ48@1386|Bacillus 91061|Bacilli M NAD-dependent epimerase dehydratase - - 5.1.3.6 ko:K08679 ko00520,ko01100,map00520,map01100 - R01385 RC00289 ko00000,ko00001,ko01000 - - - Epimerase,GDP_Man_Dehyd k141_32190_1 1279017.AQYJ01000029_gene3847 5.62e-16 75.1 COG3019@1|root,COG3019@2|Bacteria,1MZ9V@1224|Proteobacteria,1S9CQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S metal-binding protein copG - - - - - - - - - - - DUF411 k141_32190_2 1279017.AQYJ01000029_gene3850 4.76e-67 213.0 COG0429@1|root,COG0429@2|Bacteria,1MWV1@1224|Proteobacteria,1RN39@1236|Gammaproteobacteria,46554@72275|Alteromonadaceae 1236|Gammaproteobacteria S hydrolase of the alpha beta-hydrolase fold yheT GO:0003674,GO:0003824,GO:0006629,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0044237,GO:0044238,GO:0044255,GO:0050526,GO:0052689,GO:0071704 - ko:K07019 - - - - ko00000 - - - Abhydrolase_1 k141_23872_1 1294265.JCM21738_450 6.28e-81 251.0 COG4191@1|root,COG4191@2|Bacteria 2|Bacteria T Histidine kinase - - - - - - - - - - - - 7TMR-DISM_7TM,HATPase_c,PAS_9,Response_reg k141_34612_4 1122970.AUHC01000004_gene2242 3.07e-25 103.0 COG0665@1|root,COG0665@2|Bacteria,1N2VH@1224|Proteobacteria,2VGVH@28211|Alphaproteobacteria,2KE6H@204457|Sphingomonadales 204457|Sphingomonadales E tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity - - - - - - - - - - - - - k141_14416_1 1384049.CD29_05245 4.88e-70 219.0 COG0411@1|root,COG0411@2|Bacteria,1TR0P@1239|Firmicutes,4HASG@91061|Bacilli,3IXIE@400634|Lysinibacillus 91061|Bacilli E amino acid - - - ko:K01995 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C k141_18007_1 1279017.AQYJ01000027_gene1979 1.19e-91 278.0 COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,1RMBT@1236|Gammaproteobacteria,4642P@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG1194 A G-specific DNA glycosylase mutY GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - ko:K03575 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD,NUDIX_4 k141_16759_1 766499.C357_22775 3.22e-124 365.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2TQNK@28211|Alphaproteobacteria 28211|Alphaproteobacteria G COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - - - - - - - - - - DctM k141_6112_1 1453501.JELR01000002_gene866 4.29e-203 580.0 COG0457@1|root,COG0457@2|Bacteria,1NAJI@1224|Proteobacteria 1224|Proteobacteria T ATPase activity - - - - - - - - - - - - DUF1570 k141_31068_1 935836.JAEL01000002_gene524 3.08e-116 341.0 COG0195@1|root,COG0195@2|Bacteria,1TPB3@1239|Firmicutes,4HA7F@91061|Bacilli,1ZDAH@1386|Bacillus 91061|Bacilli K Participates in both transcription termination and antitermination nusA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K02600 - - - - ko00000,ko03009,ko03021 - - - KH_5,NusA_N,S1 k141_9627_1 1116375.VEJY3_04360 2.34e-68 214.0 COG0583@1|root,COG0583@2|Bacteria,1MWY0@1224|Proteobacteria,1RNMN@1236|Gammaproteobacteria,1XV8F@135623|Vibrionales 135623|Vibrionales K Transcriptional regulator - - - ko:K13636 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate k141_23873_1 1294265.JCM21738_2898 1.16e-124 367.0 COG0697@1|root,COG0697@2|Bacteria,1TP7K@1239|Firmicutes,4HBWN@91061|Bacilli,1ZAS9@1386|Bacillus 91061|Bacilli EG Bacillus/Clostridium GerA spore germination protein spoVAF - - ko:K06408 - - - - ko00000 - - - GerA k141_6113_1 935837.JAEK01000015_gene4991 3.04e-28 106.0 COG1670@1|root,COG1670@2|Bacteria,1V5D0@1239|Firmicutes,4HHID@91061|Bacilli,1ZG49@1386|Bacillus 91061|Bacilli J Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_3 k141_21572_1 42565.FP66_09975 1.37e-128 366.0 COG3017@1|root,COG3017@2|Bacteria,1N02T@1224|Proteobacteria,1S91E@1236|Gammaproteobacteria,1XKNX@135619|Oceanospirillales 135619|Oceanospirillales M Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein lolB - - ko:K02494 - - - - ko00000 - - - LolB k141_32191_1 218284.CCDN010000002_gene2273 1.09e-104 308.0 COG0861@1|root,COG0861@2|Bacteria,1TQ09@1239|Firmicutes,4HB99@91061|Bacilli,1ZBYE@1386|Bacillus 91061|Bacilli P Integral membrane protein TerC family - - - - - - - - - - - - TerC k141_26312_1 218284.CCDN010000002_gene2226 3.11e-225 629.0 COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,4H9SZ@91061|Bacilli,1ZAX7@1386|Bacillus 91061|Bacilli E Sodium alanine symporter yflA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03310 - - - - ko00000 2.A.25 - - Na_Ala_symp k141_26312_2 218284.CCDN010000002_gene2227 1.16e-199 560.0 COG0524@1|root,COG1522@1|root,COG0524@2|Bacteria,COG1522@2|Bacteria,1TQR4@1239|Firmicutes,4H9VM@91061|Bacilli,1ZBUP@1386|Bacillus 91061|Bacilli GK pfkB family carbohydrate kinase - - 2.7.1.83 ko:K16328 ko00240,map00240 - R03315 RC00002,RC00017 ko00000,ko00001,ko01000 - - - HTH_24,PfkB k141_12005_1 1123053.AUDG01000018_gene3020 1.45e-278 783.0 COG1629@1|root,COG4771@2|Bacteria,1R5B9@1224|Proteobacteria,1S13U@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Carboxypeptidase regulatory-like domain - - - - - - - - - - - - CarboxypepD_reg,Plug,TonB_dep_Rec k141_12005_2 1453501.JELR01000001_gene2448 2.49e-147 419.0 COG3047@1|root,COG3047@2|Bacteria 2|Bacteria - - ompW - - ko:K07275 - - - - ko00000 - - - OmpW k141_28698_2 714961.BFZC1_08170 3.22e-46 158.0 COG1186@1|root,COG1186@2|Bacteria,1TPSB@1239|Firmicutes,4H9N2@91061|Bacilli,3IWJ4@400634|Lysinibacillus 91061|Bacilli J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA prfB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K02836 - - - - ko00000,ko03012 - - - PCRF,RF-1 k141_22734_1 1340434.AXVA01000012_gene3026 6.39e-145 416.0 COG0535@1|root,COG0535@2|Bacteria,1TRC8@1239|Firmicutes,4HA9Q@91061|Bacilli,1ZAVK@1386|Bacillus 91061|Bacilli S YfkB-like domain yfkA - - - - - - - - - - - Fer4_12,Fer4_14,Radical_SAM,YfkB k141_4880_1 1238450.VIBNISOn1_970041 0.000734 46.2 COG0664@1|root,COG0784@1|root,COG4191@1|root,COG0664@2|Bacteria,COG0784@2|Bacteria,COG4191@2|Bacteria,1R97I@1224|Proteobacteria,1RNJ8@1236|Gammaproteobacteria,1XSZK@135623|Vibrionales 135623|Vibrionales T COG0642 Signal transduction histidine kinase VP1245 - - - - - - - - - - - HATPase_c,HisKA,Response_reg,cNMP_binding k141_31069_1 1453501.JELR01000002_gene917 1.24e-55 185.0 COG0477@1|root,COG2814@2|Bacteria,1MW19@1224|Proteobacteria,1RMSZ@1236|Gammaproteobacteria,4661G@72275|Alteromonadaceae 1236|Gammaproteobacteria EGP Major Facilitator Superfamily bcr - - ko:K07552 - - - - ko00000,ko02000 2.A.1.2 - - MFS_1 k141_18008_2 218284.CCDN010000001_gene1168 1.36e-93 274.0 COG1622@1|root,COG1622@2|Bacteria,1TPMD@1239|Firmicutes,4HGXU@91061|Bacilli,1ZAWE@1386|Bacillus 91061|Bacilli C COG1622 Heme copper-type cytochrome quinol oxidases, subunit 2 cbaB - 1.9.3.1 ko:K02275 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.4,3.D.4.6 - - COX2 k141_9873_2 1453501.JELR01000002_gene866 4.18e-145 427.0 COG0457@1|root,COG0457@2|Bacteria,1NAJI@1224|Proteobacteria 1224|Proteobacteria T ATPase activity - - - - - - - - - - - - DUF1570 k141_22993_1 1042377.AFPJ01000041_gene2672 9.41e-96 292.0 COG1538@1|root,COG1538@2|Bacteria,1MYX2@1224|Proteobacteria,1RYIR@1236|Gammaproteobacteria,46CEK@72275|Alteromonadaceae 1236|Gammaproteobacteria MU Outer membrane efflux protein - - - ko:K12543 - M00330 - - ko00000,ko00002,ko02000,ko02044 1.B.17,3.A.1.109.4 - - OEP k141_22993_2 216142.LT40_02265 4.72e-44 161.0 COG2274@1|root,COG2274@2|Bacteria,1R2T0@1224|Proteobacteria,1SBE1@1236|Gammaproteobacteria 1236|Gammaproteobacteria V COG2274 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain - - - ko:K12541,ko:K12542 ko02010,map02010 M00330 - - ko00000,ko00001,ko00002,ko02000,ko02044 3.A.1.109.3,3.A.1.109.4,8.A.1 - - ABC_membrane,ABC_tran k141_8696_1 886293.Sinac_2369 1.14e-96 302.0 COG1164@1|root,COG1164@2|Bacteria,2IX6H@203682|Planctomycetes 203682|Planctomycetes E Angiotensin-converting enzyme - - 3.4.15.1 ko:K01283 ko04614,ko04924,ko05142,ko05410,map04614,map04924,map05142,map05410 - - - ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 - - - Peptidase_M2 k141_13507_1 218284.CCDN010000008_gene4216 3.52e-53 177.0 28Z61@1|root,2ZKYB@2|Bacteria,1W2RA@1239|Firmicutes,4HSNT@91061|Bacilli,1ZIVH@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_20496_1 1453501.JELR01000002_gene323 1.89e-68 217.0 COG3712@1|root,COG3712@2|Bacteria,1MZCK@1224|Proteobacteria,1S88I@1236|Gammaproteobacteria,467V5@72275|Alteromonadaceae 1236|Gammaproteobacteria PT Domain of unknown function (DUF4880) - - - ko:K07165 - - - - ko00000 - - - DUF4880,DUF4974,FecR k141_32346_1 1408424.JHYI01000025_gene1785 9.08e-74 224.0 COG0110@1|root,COG0110@2|Bacteria,1TQEX@1239|Firmicutes,4HAJ0@91061|Bacilli,1ZDPK@1386|Bacillus 91061|Bacilli S COG0110 Acetyltransferase (isoleucine patch superfamily) maa - 2.3.1.79 ko:K00661 - - - - ko00000,ko01000 - - - CM_2,Hexapep,Hexapep_2,Mac k141_32346_2 443598.AUFA01000017_gene7381 1.8e-05 47.0 COG1231@1|root,COG1231@2|Bacteria,1P3D9@1224|Proteobacteria,2TVTX@28211|Alphaproteobacteria,3JVYG@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - 1.4.3.4 ko:K00274 ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034 M00135 R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354 RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713 ko00000,ko00001,ko00002,ko01000 - - - Amino_oxidase,NAD_binding_8 k141_25322_2 218284.CCDN010000006_gene3740 5.07e-131 379.0 COG1609@1|root,COG1609@2|Bacteria,1TPZM@1239|Firmicutes,4H9ZT@91061|Bacilli,1ZB2U@1386|Bacillus 91061|Bacilli K Transcriptional regulator malR - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_1,Peripla_BP_3 k141_29981_1 1198452.Jab_1c06030 3.98e-13 73.6 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,2VIRZ@28216|Betaproteobacteria,473SJ@75682|Oxalobacteraceae 28216|Betaproteobacteria P TonB-dependent Receptor Plug Domain - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_15810_1 223926.28809558 9.56e-120 371.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1XSPS@135623|Vibrionales 135623|Vibrionales U COG0841 Cation multidrug efflux pump acrF - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran k141_28907_1 1453501.JELR01000002_gene477 6.63e-112 328.0 COG3386@1|root,COG3386@2|Bacteria,1MXVD@1224|Proteobacteria,1RZMF@1236|Gammaproteobacteria,46ADZ@72275|Alteromonadaceae 1236|Gammaproteobacteria G SMP-30/Gluconolaconase/LRE-like region gnl - 3.1.1.17 ko:K01053 ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220 M00129 R01519,R02933,R03751 RC00537,RC00983 ko00000,ko00001,ko00002,ko01000,ko04147 - - - SGL k141_28907_2 1453501.JELR01000002_gene476 2e-15 76.6 COG3525@1|root,COG3525@2|Bacteria,1MVDE@1224|Proteobacteria,1RMNI@1236|Gammaproteobacteria,465UJ@72275|Alteromonadaceae 1236|Gammaproteobacteria G Glycosyl hydrolase family 20, domain 2 nahA - 3.2.1.52 ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 M00079 R00022,R06004,R11316 RC00049 ko00000,ko00001,ko00002,ko01000,ko03110 - GH20 - CHB_HEX_C_1,Glyco_hydro_20,Glyco_hydro_20b k141_453_1 1042377.AFPJ01000007_gene1863 4.43e-12 66.6 COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,1RN05@1236|Gammaproteobacteria,464MR@72275|Alteromonadaceae 1236|Gammaproteobacteria S Insulinase (Peptidase family M16) pqqL - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C k141_453_2 930169.B5T_01211 1.79e-77 234.0 COG2329@1|root,COG2329@2|Bacteria,1RAC6@1224|Proteobacteria,1S480@1236|Gammaproteobacteria,1XPP2@135619|Oceanospirillales 135619|Oceanospirillales S Domain of unknown function (DUF3291) - - - - - - - - - - - - DUF3291 k141_453_3 697282.Mettu_4019 1.57e-55 177.0 COG1371@1|root,COG1371@2|Bacteria,1RJU0@1224|Proteobacteria,1S8F6@1236|Gammaproteobacteria,1XFH0@135618|Methylococcales 135618|Methylococcales S Archease protein family (MTH1598/TM1083) - - - - - - - - - - - - Archease k141_453_4 1123393.KB891316_gene1685 3.85e-250 697.0 COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,2VJ89@28216|Betaproteobacteria,1KRE8@119069|Hydrogenophilales 119069|Hydrogenophilales S tRNA-splicing ligase RtcB - - 6.5.1.3 ko:K14415 - - - - ko00000,ko01000,ko03016 - - - RtcB k141_4005_1 439292.Bsel_1476 8.51e-116 355.0 COG0243@1|root,COG0243@2|Bacteria,1TPZG@1239|Firmicutes 1239|Firmicutes C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family nasC - 1.8.5.3,1.8.5.5 ko:K00372,ko:K07306,ko:K08352 ko00910,ko00920,ko01120,map00910,map00920,map01120 M00531 R00798,R01106,R09501,R10149 RC02555,RC02812,RC02823 ko00000,ko00001,ko00002,ko01000,ko02000 5.A.3.3,5.A.3.5 - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal k141_13508_2 1294265.JCM21738_2042 1.92e-87 261.0 COG3854@1|root,COG3854@2|Bacteria,1TQ23@1239|Firmicutes,4HA2K@91061|Bacilli,1ZAWB@1386|Bacillus 91061|Bacilli S stage III sporulation protein AA spoIIIAA - - ko:K06390 - - - - ko00000 - - - AAA,T2SSE k141_12350_2 1116375.VEJY3_13165 9.08e-93 273.0 COG1546@1|root,COG1546@2|Bacteria,1RH2Y@1224|Proteobacteria,1S5WH@1236|Gammaproteobacteria,1XXEF@135623|Vibrionales 135623|Vibrionales S Belongs to the CinA family - - 3.5.1.42 ko:K03743 ko00760,map00760 - R02322 RC00100 ko00000,ko00001,ko01000 - - - CinA k141_12350_4 345073.VC395_0560 3.83e-215 600.0 COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,1RMHP@1236|Gammaproteobacteria,1XSES@135623|Vibrionales 135623|Vibrionales L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage recA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - ko:K03553 ko03440,map03440 M00729 - - ko00000,ko00001,ko00002,ko03400 - - - RecA k141_12350_5 1116375.VEJY3_11855 1.01e-274 753.0 2CHG1@1|root,32YZS@2|Bacteria,1NBVV@1224|Proteobacteria,1RYDN@1236|Gammaproteobacteria,1XUP3@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_12350_6 1116375.VEJY3_11850 1.8e-251 692.0 2BWPZ@1|root,2ZBDX@2|Bacteria,1MUFD@1224|Proteobacteria,1S11I@1236|Gammaproteobacteria,1XWRE@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_31264_2 218284.CCDN010000005_gene3218 1.59e-121 348.0 COG4903@1|root,COG4903@2|Bacteria,1V4S5@1239|Firmicutes,4HHF4@91061|Bacilli,1ZGB4@1386|Bacillus 91061|Bacilli K Competence transcription factor comK - - ko:K02250 ko02024,map02024 - - - ko00000,ko00001,ko02044,ko03000 - - - ComK k141_19350_1 218284.CCDN010000004_gene3118 1.18e-61 192.0 COG0394@1|root,COG0394@2|Bacteria,1U8S1@1239|Firmicutes,4IIQ8@91061|Bacilli,1ZNXR@1386|Bacillus 91061|Bacilli T Low molecular weight phosphatase family - - - - - - - - - - - - - k141_19350_2 218284.CCDN010000004_gene3117 1.75e-92 278.0 COG1533@1|root,COG1533@2|Bacteria,1TPA3@1239|Firmicutes,4HACB@91061|Bacilli,1ZBPU@1386|Bacillus 91061|Bacilli L Spore photoproduct lyase splB GO:0003674,GO:0003824,GO:0003913,GO:0005488,GO:0005575,GO:0005623,GO:0016829,GO:0016830,GO:0042601,GO:0042763,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0070283,GO:0140097 4.1.99.14 ko:K03716 - - - - ko00000,ko01000 - - - - k141_9875_1 1312959.KI914622_gene2317 2.75e-06 48.9 COG2259@1|root,COG2259@2|Bacteria,2IQ5C@201174|Actinobacteria,1W9YU@1268|Micrococcaceae 201174|Actinobacteria S DoxX - - - ko:K15977 - - - - ko00000 - - - DoxX k141_9875_2 575540.Isop_2172 1.14e-43 164.0 COG3383@1|root,COG3383@2|Bacteria,2J4XN@203682|Planctomycetes 203682|Planctomycetes C 2Fe-2S iron-sulfur cluster binding domain - - 1.17.1.9 ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001,ko01000 - - - Fer2_4,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3 k141_35950_2 1288298.rosmuc_01160 9.81e-103 305.0 COG1335@1|root,COG1335@2|Bacteria,1N48X@1224|Proteobacteria,2U17G@28211|Alphaproteobacteria,46PSA@74030|Roseovarius 28211|Alphaproteobacteria Q Related to nicotinamidase - - - - - - - - - - - - Isochorismatase k141_454_1 218284.CCDN010000001_gene1448 9.45e-113 328.0 COG0619@1|root,COG0619@2|Bacteria,1TUDZ@1239|Firmicutes,4HER7@91061|Bacilli,1ZPZE@1386|Bacillus 91061|Bacilli P Cobalt transport protein ykoC - - ko:K16785 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - CbiQ k141_1495_1 218284.CCDN010000001_gene777 5.03e-95 280.0 COG5663@1|root,COG5663@2|Bacteria,1V2IT@1239|Firmicutes,4HG86@91061|Bacilli,1ZDPA@1386|Bacillus 91061|Bacilli S Belongs to the 5'(3')-deoxyribonucleotidase family yqfW - - ko:K05967 - - - - ko00000 - - - NT5C k141_32347_1 1196031.ALEG01000020_gene3037 7.73e-14 70.1 COG0226@1|root,COG0226@2|Bacteria,1TQ5X@1239|Firmicutes,4HBEB@91061|Bacilli,1ZB22@1386|Bacillus 91061|Bacilli P Phosphate pstS GO:0003674,GO:0005488,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015698,GO:0042301,GO:0043167,GO:0043168,GO:0051179,GO:0051234 - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - PBP_like_2 k141_32347_2 1307436.PBF_02530 2e-39 135.0 2EA57@1|root,334A4@2|Bacteria,1VHEA@1239|Firmicutes,4HQU5@91061|Bacilli,1ZRA3@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_15811_1 218284.CCDN010000002_gene2731 5.04e-90 282.0 COG3711@1|root,COG3711@2|Bacteria,1TQT1@1239|Firmicutes,4HABH@91061|Bacilli,1ZBYI@1386|Bacillus 91061|Bacilli K transcriptional regulator, MtlR mtlR - - ko:K03483 - - - - ko00000,ko03000 - - - HTH_11,Mga,PRD,PTS_EIIA_2,PTS_IIB k141_20497_2 1279017.AQYJ01000027_gene1854 2.09e-78 236.0 COG1607@1|root,COG1607@2|Bacteria,1MZAZ@1224|Proteobacteria,1SA9N@1236|Gammaproteobacteria,467IG@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1607 Acyl-CoA hydrolase yciA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0047617,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 - ko:K10806 ko01040,map01040 - - - ko00000,ko00001,ko01000,ko01004 - - - 4HBT k141_28908_1 479434.Sthe_0485 1.74e-44 165.0 COG0457@1|root,COG1396@1|root,COG3903@1|root,COG0457@2|Bacteria,COG1396@2|Bacteria,COG3903@2|Bacteria,2G7W3@200795|Chloroflexi,27ZD0@189775|Thermomicrobia 200795|Chloroflexi K Tetratricopeptide repeat - - - - - - - - - - - - GerE,TPR_12 k141_29982_2 1453501.JELR01000002_gene1240 5.78e-44 147.0 COG1380@1|root,COG1380@2|Bacteria 2|Bacteria S Effector of murein hydrolase LrgA lrgA GO:0000270,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0006810,GO:0008104,GO:0008150,GO:0008152,GO:0008565,GO:0009056,GO:0009057,GO:0009253,GO:0015031,GO:0015833,GO:0016020,GO:0030203,GO:0033036,GO:0042886,GO:0043170,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - ko:K05338,ko:K06518 ko02020,map02020 - - - ko00000,ko00001,ko02000 1.E.14.1,1.E.14.2 - - LrgA k141_12351_1 866895.HBHAL_2000 3.56e-104 317.0 COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HB3V@91061|Bacilli,3ND2G@45667|Halobacillus 91061|Bacilli IQ AMP-binding enzyme C-terminal domain - - - ko:K00666 - - - - ko00000,ko01000,ko01004 - - - AMP-binding,AMP-binding_C k141_9876_1 1283337.B0ZSJ3_BPHA1 2.46e-12 64.3 4QCX5@10239|Viruses,4QVAG@35237|dsDNA viruses no RNA stage,4QPPT@28883|Caudovirales,4QJXH@10662|Myoviridae 10662|Myoviridae S Glycosyl hydrolase 108 - - - - - - - - - - - - - k141_22996_2 1122217.KB899578_gene1794 6.44e-07 55.1 COG1792@1|root,COG1792@2|Bacteria,1TR1V@1239|Firmicutes,4H2TV@909932|Negativicutes 909932|Negativicutes M Involved in formation and maintenance of cell shape mreC - - ko:K03570 - - - - ko00000,ko03036 9.B.157.1 - - MreC k141_6416_2 218284.CCDN010000001_gene712 4.47e-107 310.0 COG2179@1|root,COG2179@2|Bacteria,1V6KM@1239|Firmicutes,4HGAV@91061|Bacilli,1ZFKN@1386|Bacillus 91061|Bacilli S hydrolase of the HAD superfamily yqeG - - ko:K07015 - - - - ko00000 - - - HAD_2,Hydrolase,Hydrolase_like,PGP_phosphatase k141_6416_3 218284.CCDN010000001_gene713 7.68e-73 228.0 COG1161@1|root,COG1161@2|Bacteria,1TPM2@1239|Firmicutes,4HAAF@91061|Bacilli,1ZBES@1386|Bacillus 91061|Bacilli S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis yqeH GO:0003674,GO:0003824,GO:0003924,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019219,GO:0019222,GO:0022613,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0042254,GO:0044085,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0071840,GO:0080090,GO:0090329,GO:2000104,GO:2000112,GO:2000113 - ko:K06948 - - - - ko00000,ko03009 - - - MMR_HSR1 k141_16992_1 218284.CCDN010000008_gene4218 1.51e-267 733.0 COG2309@1|root,COG2309@2|Bacteria,1TP65@1239|Firmicutes,4HBUQ@91061|Bacilli,1ZD71@1386|Bacillus 91061|Bacilli E aminopeptidase pepS - - ko:K19689 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M29 k141_14585_1 218284.CCDN010000001_gene1402 1.05e-21 86.3 COG1937@1|root,COG1937@2|Bacteria,1VFB9@1239|Firmicutes,4HNVQ@91061|Bacilli,1ZHTP@1386|Bacillus 91061|Bacilli S protein conserved in bacteria csoR - - - - - - - - - - - Trns_repr_metal k141_14585_2 218284.CCDN010000001_gene1403 1.31e-46 149.0 COG0425@1|root,COG0425@2|Bacteria,1VEEC@1239|Firmicutes,4HNQT@91061|Bacilli,1ZI1V@1386|Bacillus 91061|Bacilli O Belongs to the sulfur carrier protein TusA family yrkI GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008 - - - - - - - - - - TusA k141_14585_3 218284.CCDN010000001_gene1404 1.3e-53 171.0 COG2210@1|root,COG2210@2|Bacteria,1V2R5@1239|Firmicutes,4HG2Y@91061|Bacilli,1ZC42@1386|Bacillus 91061|Bacilli O DsrE/DsrF/DrsH-like family yrkE - - - - - - - - - - - DrsE_2,Rhodanese,TusA k141_455_1 225937.HP15_1414 9.53e-162 460.0 COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,1RN8W@1236|Gammaproteobacteria 1236|Gammaproteobacteria BQ COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein - - - - - - - - - - - - Hist_deacetyl k141_9877_1 218284.CCDN010000001_gene1164 1.77e-96 299.0 COG1199@1|root,COG1199@2|Bacteria,1TRNV@1239|Firmicutes,4HBYD@91061|Bacilli,1ZARY@1386|Bacillus 91061|Bacilli KL COG1199 Rad3-related DNA helicases ypvA - 3.6.4.12 ko:K03722 - - - - ko00000,ko01000,ko03400 - - - Helicase_C_2 k141_24100_1 1116375.VEJY3_20006 0.0 1048.0 COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,1RPX3@1236|Gammaproteobacteria,1XU8U@135623|Vibrionales 135623|Vibrionales F Belongs to the 5'-nucleotidase family - - 3.1.3.5 ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - 5_nucleotid_C,Metallophos k141_24100_2 1116375.VEJY3_20011 0.0 1032.0 COG1196@1|root,COG3593@1|root,COG1196@2|Bacteria,COG3593@2|Bacteria,1N2CB@1224|Proteobacteria,1RQN2@1236|Gammaproteobacteria,1XSQI@135623|Vibrionales 135623|Vibrionales L ATP-dependent endonuclease of the OLD family ybjD - - ko:K07459 - - - - ko00000 - - - DUF2813 k141_24100_3 223926.28809088 9.32e-103 298.0 28NYX@1|root,2ZBVY@2|Bacteria,1RA69@1224|Proteobacteria,1S1YX@1236|Gammaproteobacteria,1XWYY@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF1097) ycdZ - - - - - - - - - - - DUF1097 k141_9910_2 794846.AJQU01000107_gene5257 4.98e-66 221.0 COG0577@1|root,COG0577@2|Bacteria,1MW6D@1224|Proteobacteria,2TTJZ@28211|Alphaproteobacteria,4B8CP@82115|Rhizobiaceae 28211|Alphaproteobacteria V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD k141_13550_1 1453501.JELR01000005_gene1689 5.26e-64 199.0 COG2717@1|root,COG2717@2|Bacteria,1RDUP@1224|Proteobacteria,1RS9K@1236|Gammaproteobacteria,4686M@72275|Alteromonadaceae 1236|Gammaproteobacteria C Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain msrQ GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010181,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0019538,GO:0020037,GO:0030091,GO:0031224,GO:0031226,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046906,GO:0048037,GO:0050662,GO:0055114,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564 - ko:K17247 - - - - ko00000 - - - Ferric_reduct k141_20522_1 59919.PMM0581 1.67e-08 53.5 COG3794@1|root,COG3794@2|Bacteria,1G6Z2@1117|Cyanobacteria,1MMEW@1212|Prochloraceae 1117|Cyanobacteria C Alternative locus ID petE - - ko:K02638 ko00195,map00195 - - - ko00000,ko00001,ko00194 - - - Copper-bind k141_5116_1 218284.CCDN010000009_gene4314 1.2e-23 95.1 COG2200@1|root,COG2200@2|Bacteria,1V6YK@1239|Firmicutes,4HIIM@91061|Bacilli,1ZH5W@1386|Bacillus 91061|Bacilli T Putative diguanylate phosphodiesterase - - - - - - - - - - - - EAL k141_37150_1 1453501.JELR01000002_gene1358 3.49e-130 378.0 COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,1RMBT@1236|Gammaproteobacteria,4642P@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG1194 A G-specific DNA glycosylase mutY GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - ko:K03575 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD,NUDIX_4 k141_7464_1 218284.CCDN010000002_gene2938 1.37e-111 336.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,1ZAY7@1386|Bacillus 91061|Bacilli V ABC transporter ygaD GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702 - ko:K11085 ko02010,map02010 - - - ko00000,ko00001,ko01000,ko02000 3.A.1.106 - - ABC_membrane,ABC_tran k141_17014_1 218284.CCDN010000005_gene3257 6.78e-62 196.0 COG1307@1|root,COG1307@2|Bacteria,1TQDI@1239|Firmicutes,4HAYQ@91061|Bacilli,1ZCK2@1386|Bacillus 91061|Bacilli S protein conserved in bacteria yitS - - - - - - - - - - - DegV k141_13551_2 1453501.JELR01000002_gene692 4.17e-58 187.0 COG0517@1|root,COG0517@2|Bacteria,1RJTX@1224|Proteobacteria,1S6K2@1236|Gammaproteobacteria,467TZ@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0517 FOG CBS domain - - - - - - - - - - - - CBS k141_12378_1 1382305.AZUC01000052_gene3146 1.18e-33 128.0 28JE7@1|root,2Z98F@2|Bacteria,1UZ9J@1239|Firmicutes,4HHJH@91061|Bacilli 91061|Bacilli S Domain of unknown function (DUF4179) - - - - - - - - - - - - DUF4179 k141_12378_2 1243664.CAVL020000047_gene2336 1.62e-36 129.0 COG1595@1|root,COG1595@2|Bacteria,1V6CD@1239|Firmicutes,4HI3W@91061|Bacilli,1ZGT8@1386|Bacillus 91061|Bacilli K Sigma-70, region 4 - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_26721_1 218284.CCDN010000007_gene3882 7.12e-55 173.0 2EE71@1|root,3381J@2|Bacteria,1V9B0@1239|Firmicutes,4HJ2A@91061|Bacilli,1ZHAU@1386|Bacillus 91061|Bacilli S gas vesicle protein gvpU - - - - - - - - - - - - k141_6431_1 1294265.JCM21738_4719 9.62e-132 397.0 COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,4HAFP@91061|Bacilli,1ZBJ3@1386|Bacillus 91061|Bacilli V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran k141_6431_2 224324.aq_1672 8.22e-05 45.8 COG0542@1|root,COG0542@2|Bacteria,2G3N7@200783|Aquificae 200783|Aquificae O Belongs to the ClpA ClpB family clpB - - ko:K03695,ko:K03696 ko01100,ko04213,map01100,map04213 - - - ko00000,ko00001,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N,UVR k141_23028_1 491915.Aflv_0673 1.61e-114 361.0 COG5283@1|root,COG5412@1|root,COG5283@2|Bacteria,COG5412@2|Bacteria,1TQ28@1239|Firmicutes,4HAFE@91061|Bacilli,21W37@150247|Anoxybacillus 91061|Bacilli S Phage tail tape measure protein - - - - - - - - - - - - Peptidase_M23,PhageMin_Tail,SLT k141_28924_2 1116375.VEJY3_19281 2.68e-164 463.0 COG0583@1|root,COG0583@2|Bacteria,1R8Z6@1224|Proteobacteria,1S1YG@1236|Gammaproteobacteria,1XVMQ@135623|Vibrionales 135623|Vibrionales K COG0583 Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_31280_1 218284.CCDN010000002_gene2874 3.94e-155 447.0 COG3333@1|root,COG3333@2|Bacteria,1TPE7@1239|Firmicutes,4HADN@91061|Bacilli,1ZBVK@1386|Bacillus 91061|Bacilli S Tripartite tricarboxylate transporter TctA family tctA - - ko:K07793 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.80.1 - - TctA k141_20523_1 1042377.AFPJ01000012_gene1335 4.41e-53 175.0 COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,1RNJK@1236|Gammaproteobacteria,464DZ@72275|Alteromonadaceae 1236|Gammaproteobacteria D COG1192 ATPases involved in chromosome partitioning parA - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 k141_32365_1 1195246.AGRI_12836 2.5e-24 102.0 COG0760@1|root,COG0760@2|Bacteria,1RDD3@1224|Proteobacteria,1S2D7@1236|Gammaproteobacteria,465VA@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG0760 Parvulin-like peptidyl-prolyl isomerase - - 5.2.1.8 ko:K03769 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_3 k141_32365_2 1279017.AQYJ01000027_gene1680 2.2e-82 249.0 COG2181@1|root,COG2181@2|Bacteria,1MXGZ@1224|Proteobacteria,1RPTD@1236|Gammaproteobacteria,465ID@72275|Alteromonadaceae 1236|Gammaproteobacteria C nitrate reductase, gamma subunit narI - 1.7.5.1 ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 M00529,M00530 R00798,R01106,R09497 RC02812 ko00000,ko00001,ko00002,ko01000 5.A.3.1 - - Nitrate_red_gam k141_25350_1 749413.E5DV54_9VIRU 2.46e-40 145.0 4QC5Z@10239|Viruses,4QUNP@35237|dsDNA viruses no RNA stage 10239|Viruses S Phage Mu protein F like protein - GO:0005575,GO:0019012,GO:0019028,GO:0044423,GO:0046729 - - - - - - - - - - - k141_1517_1 218284.CCDN010000002_gene2107 6.46e-201 559.0 COG0022@1|root,COG0022@2|Bacteria,1TP3J@1239|Firmicutes,4HAEB@91061|Bacilli,1ZBM7@1386|Bacillus 91061|Bacilli C Transketolase, C-terminal domain pdhB2 - 1.2.4.1 ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C k141_34820_2 1279017.AQYJ01000027_gene1787 9.57e-219 610.0 COG1092@1|root,COG1092@2|Bacteria,1MUGB@1224|Proteobacteria,1RN7Z@1236|Gammaproteobacteria,464TP@72275|Alteromonadaceae 1236|Gammaproteobacteria J Specifically methylates the cytosine at position 1962 (m5C1962) of 23S rRNA rlmI - 2.1.1.191 ko:K06969 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_SAM k141_34820_4 1453501.JELR01000002_gene1107 1.79e-95 281.0 COG0241@1|root,COG0241@2|Bacteria,1RDGR@1224|Proteobacteria,1S3UD@1236|Gammaproteobacteria,467KG@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0241 Histidinol phosphatase and related phosphatases gmhB - 3.1.3.82,3.1.3.83 ko:K03273 ko00540,ko01100,map00540,map01100 M00064 R05647,R09771 RC00017 ko00000,ko00001,ko00002,ko01000,ko01005 - - iJN746.PP_0059 Hydrolase_like k141_34820_5 1279017.AQYJ01000027_gene1781 0.0 1105.0 COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,1RNR3@1236|Gammaproteobacteria,464RV@72275|Alteromonadaceae 1236|Gammaproteobacteria J Glycyl-tRNA synthetase beta subunit glyS GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.14 ko:K01879 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iAPECO1_1312.APECO1_2891,iE2348C_1286.E2348C_3810,iECABU_c1320.ECABU_c40010,iECED1_1282.ECED1_4242,iECH74115_1262.ECH74115_4934,iECNA114_1301.ECNA114_3710,iECOK1_1307.ECOK1_4005,iECP_1309.ECP_3661,iECS88_1305.ECS88_3976,iECSF_1327.ECSF_3393,iECSP_1301.ECSP_4554,iECs_1301.ECs4442,iG2583_1286.G2583_4300,iUMN146_1321.UM146_17960,iUTI89_1310.UTI89_C4099,ic_1306.c4378 DALR_1,tRNA_synt_2f k141_18254_2 218284.CCDN010000001_gene1056 1.06e-195 550.0 COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,4HAHH@91061|Bacilli,1ZBRQ@1386|Bacillus 91061|Bacilli M Belongs to the peptidase S11 family dacB GO:0003674,GO:0003824,GO:0004175,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.16.4 ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - PBP5_C,Peptidase_S11 k141_9914_1 665952.HMPREF1015_01026 1.44e-139 401.0 COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,4HAG5@91061|Bacilli,1ZCUX@1386|Bacillus 91061|Bacilli L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage recA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009292,GO:0009294,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0050896,GO:0051704,GO:0051716,GO:0071496 - ko:K03553 ko03440,map03440 M00729 - - ko00000,ko00001,ko00002,ko03400 - - - RecA k141_487_1 218284.CCDN010000002_gene2877 7.52e-88 260.0 COG1607@1|root,COG1607@2|Bacteria,1V3S2@1239|Firmicutes,4HJ0Z@91061|Bacilli,1ZGG1@1386|Bacillus 91061|Bacilli I Thioesterase superfamily - - - - - - - - - - - - 4HBT k141_13553_1 1453501.JELR01000001_gene2246 1.55e-08 53.5 COG3019@1|root,COG3019@2|Bacteria,1MZ9V@1224|Proteobacteria,1S9CQ@1236|Gammaproteobacteria,46779@72275|Alteromonadaceae 1236|Gammaproteobacteria S metal-binding protein copG - - - - - - - - - - - DUF411 k141_23030_1 1196028.ALEF01000018_gene2358 5.25e-56 181.0 COG1296@1|root,COG1296@2|Bacteria,1TSXD@1239|Firmicutes,4HCET@91061|Bacilli,4C4MT@84406|Virgibacillus 91061|Bacilli E AzlC protein ygaZ - - - - - - - - - - - AzlC k141_8742_1 218284.CCDN010000001_gene79 9.17e-130 379.0 COG0849@1|root,COG0849@2|Bacteria,1TP1Z@1239|Firmicutes,4H9NF@91061|Bacilli,1ZBH1@1386|Bacillus 91061|Bacilli D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring ftsA GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032153,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0098552,GO:0098562 - ko:K03590 ko04112,map04112 - - - ko00000,ko00001,ko03036,ko04812 - - - DUF3484,FtsA,SHS2_FTSA k141_6566_2 1196324.A374_08949 1.96e-62 215.0 COG1196@1|root,COG1196@2|Bacteria,1TQY7@1239|Firmicutes,4HCRF@91061|Bacilli 91061|Bacilli D Psort location Cytoplasmic, score - - - - - - - - - - - - AAA_23,AAA_27 k141_19639_1 1042377.AFPJ01000036_gene1264 9.16e-88 270.0 2DB9X@1|root,2Z7ZS@2|Bacteria,1N6CK@1224|Proteobacteria,1S87D@1236|Gammaproteobacteria,46DMG@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF3445) - - - - - - - - - - - - DUF3445 k141_19639_2 1453501.JELR01000001_gene2649 4.7e-173 490.0 COG2207@1|root,COG2207@2|Bacteria,1R5D8@1224|Proteobacteria,1RYEI@1236|Gammaproteobacteria,46B2H@72275|Alteromonadaceae 1236|Gammaproteobacteria K Arabinose-binding domain of AraC transcription regulator, N-term - - - - - - - - - - - - Arabinose_bd,HTH_18 k141_19639_3 1453501.JELR01000001_gene2648 3.42e-273 753.0 COG2072@1|root,COG2072@2|Bacteria,1MUQH@1224|Proteobacteria,1RY92@1236|Gammaproteobacteria,466U4@72275|Alteromonadaceae 1236|Gammaproteobacteria P flavoprotein involved in K transport - - - ko:K07222 - - - - ko00000 - - - FMO-like,Pyr_redox_3 k141_19639_4 1453501.JELR01000001_gene2647 1.69e-161 460.0 COG0385@1|root,COG0385@2|Bacteria,1MXF3@1224|Proteobacteria,1RNZF@1236|Gammaproteobacteria,46A32@72275|Alteromonadaceae 1236|Gammaproteobacteria S SBF-like CPA transporter family (DUF4137) - - - ko:K03453 - - - - ko00000 2.A.28 - - SBF k141_19639_5 1279017.AQYJ01000025_gene497 2.96e-151 434.0 COG0451@1|root,COG0451@2|Bacteria,1N8PG@1224|Proteobacteria,1RWCX@1236|Gammaproteobacteria,469BZ@72275|Alteromonadaceae 1236|Gammaproteobacteria GM NAD-dependent epimerase dehydratase - - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase k141_19639_6 1453501.JELR01000001_gene2645 7.37e-130 377.0 COG0300@1|root,COG0300@2|Bacteria,1NH6F@1224|Proteobacteria,1S0XK@1236|Gammaproteobacteria,46ACT@72275|Alteromonadaceae 1236|Gammaproteobacteria S KR domain - - - - - - - - - - - - adh_short k141_19639_7 631362.Thi970DRAFT_01806 3.71e-12 69.3 2C5P4@1|root,3310H@2|Bacteria,1N6V1@1224|Proteobacteria,1S6FW@1236|Gammaproteobacteria,1WYIC@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - k141_19639_8 589865.DaAHT2_0479 2.85e-39 139.0 COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,42U0T@68525|delta/epsilon subdivisions,2WRBN@28221|Deltaproteobacteria,2MPZD@213118|Desulfobacterales 28221|Deltaproteobacteria O Hsp20/alpha crystallin family - - - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 k141_19639_9 1042377.AFPJ01000036_gene1269 5.89e-99 291.0 COG1280@1|root,COG1280@2|Bacteria,1RET0@1224|Proteobacteria,1T02W@1236|Gammaproteobacteria,46CSZ@72275|Alteromonadaceae 1236|Gammaproteobacteria E LysE type translocator - - - - - - - - - - - - LysE k141_19639_10 1042377.AFPJ01000036_gene1270 2.61e-108 321.0 COG0084@1|root,COG0084@2|Bacteria,1MW5C@1224|Proteobacteria,1RP5T@1236|Gammaproteobacteria,46719@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG0084 Mg-dependent DNase yjjV - - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase k141_24327_1 218284.CCDN010000006_gene3744 4.25e-64 206.0 COG1653@1|root,COG1653@2|Bacteria,1U4H4@1239|Firmicutes,4HBJP@91061|Bacilli,1ZCZR@1386|Bacillus 91061|Bacilli G Bacterial extracellular solute-binding protein malE - - ko:K02027 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - SBP_bac_1,SBP_bac_8 k141_24327_2 406124.ACPC01000020_gene3787 5.77e-50 176.0 COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,4HAAG@91061|Bacilli,1ZPV2@1386|Bacillus 91061|Bacilli G Belongs to the glycosyl hydrolase 3 family bglX - 3.2.1.21,3.2.1.52 ko:K01207,ko:K05349 ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501 M00628 R00022,R00026,R02558,R02887,R02985,R03527,R04949,R04998,R05963,R07809,R07810,R10035,R10039,R10040,R10831 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko00002,ko01000 - GH3 - Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C k141_13842_1 7260.FBpp0251783 1.44e-17 87.4 COG5021@1|root,KOG0941@2759|Eukaryota,38BET@33154|Opisthokonta,3BB1I@33208|Metazoa,3CRW4@33213|Bilateria,41X76@6656|Arthropoda,3SGU0@50557|Insecta,44ZTN@7147|Diptera,45T5V@7214|Drosophilidae 33208|Metazoa O Ubiquitin-protein transferase activity HERC4 GO:0000003,GO:0000209,GO:0001650,GO:0002682,GO:0002684,GO:0003674,GO:0003824,GO:0004842,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0007276,GO:0007283,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009966,GO:0009967,GO:0009968,GO:0009987,GO:0010646,GO:0010647,GO:0010648,GO:0016567,GO:0016740,GO:0019538,GO:0019787,GO:0019941,GO:0019953,GO:0022414,GO:0023051,GO:0023056,GO:0023057,GO:0030163,GO:0031347,GO:0031349,GO:0031974,GO:0031981,GO:0032446,GO:0032501,GO:0032504,GO:0032879,GO:0032880,GO:0034121,GO:0034123,GO:0034124,GO:0034126,GO:0035330,GO:0035331,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044452,GO:0044464,GO:0044703,GO:0045088,GO:0045089,GO:0048232,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048585,GO:0048609,GO:0050776,GO:0050778,GO:0050789,GO:0050794,GO:0051603,GO:0051704,GO:0051865,GO:0060341,GO:0061630,GO:0061659,GO:0065007,GO:0070013,GO:0070647,GO:0071704,GO:0080134,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902531,GO:1902532,GO:1903076,GO:1903078,GO:1903827,GO:1903829,GO:1904375,GO:1904377,GO:1905475,GO:1905477 2.3.2.26 ko:K10614,ko:K10615 ko04120,map04120 - - - ko00000,ko00001,ko01000,ko04121 - - - HECT,RCC1 k141_23268_1 218284.CCDN010000004_gene3035 3.02e-64 207.0 COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,4HA95@91061|Bacilli,1ZCW9@1386|Bacillus 91061|Bacilli E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids alr - 5.1.1.1,5.1.1.5 ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 - R00401 RC00285 ko00000,ko00001,ko01000,ko01011 - - - Ala_racemase_C,Ala_racemase_N k141_23268_3 997296.PB1_05917 3.06e-73 220.0 COG2337@1|root,COG2337@2|Bacteria,1V6DK@1239|Firmicutes,4HGXF@91061|Bacilli,1ZG8R@1386|Bacillus 91061|Bacilli L Toxic component of a toxin-antitoxin (TA) module ndoA - - ko:K07171 - - - - ko00000,ko01000,ko02048 - - - PemK_toxin k141_4182_1 1042377.AFPJ01000045_gene2584 2.64e-87 269.0 COG0477@1|root,COG2814@2|Bacteria,1MUZ8@1224|Proteobacteria,1T1NH@1236|Gammaproteobacteria,46DC9@72275|Alteromonadaceae 1236|Gammaproteobacteria EGP Acetyl-coenzyme A transporter 1 ampG GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015672,GO:0015835,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1901264,GO:1902600 - ko:K08218 ko01501,map01501 M00628 - - ko00000,ko00001,ko00002,ko02000 2.A.1.25 - - MFS_1 k141_4182_2 1279017.AQYJ01000023_gene3255 1.97e-24 94.0 COG3695@1|root,COG3695@2|Bacteria,1N7J2@1224|Proteobacteria,1SCIZ@1236|Gammaproteobacteria,468DQ@72275|Alteromonadaceae 1236|Gammaproteobacteria L methylated DNA-protein cysteine methyltransferase ybaZ GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0005488,GO:0005515,GO:0019899,GO:0097159,GO:1901363 - ko:K07443 - - - - ko00000 - - - DNA_binding_1 k141_10234_2 1294265.JCM21738_4523 7.01e-63 196.0 COG1585@1|root,COG1585@2|Bacteria,1V4S8@1239|Firmicutes,4HHUI@91061|Bacilli,1ZGPJ@1386|Bacillus 91061|Bacilli OU Membrane protein implicated in regulation of membrane protease activity yuaF - - - - - - - - - - - - k141_33892_1 1042377.AFPJ01000043_gene887 1.72e-82 273.0 COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,1RYP9@1236|Gammaproteobacteria,465IE@72275|Alteromonadaceae 1236|Gammaproteobacteria E ERAP1-like C-terminal domain - - 3.4.11.14 ko:K01263 - - - - ko00000,ko01000 - - - ERAP1_C,Peptidase_M1 k141_37368_2 1042377.AFPJ01000007_gene1869 5e-114 337.0 COG5621@1|root,COG5621@2|Bacteria,1MUVF@1224|Proteobacteria,1RZ65@1236|Gammaproteobacteria,466MJ@72275|Alteromonadaceae 1236|Gammaproteobacteria S secreted hydrolase attH - - - - - - - - - - - CrtC,Lipocalin_9 k141_12654_2 218284.CCDN010000001_gene1078 9.31e-36 126.0 COG0517@1|root,COG0517@2|Bacteria,1TR5G@1239|Firmicutes,4H9ZA@91061|Bacilli,1ZD7H@1386|Bacillus 91061|Bacilli S CBS domain - - - - - - - - - - - - CBS k141_10235_1 637905.SVI_3717 1.24e-74 248.0 COG4934@1|root,COG4934@2|Bacteria,1QUGS@1224|Proteobacteria,1RQUN@1236|Gammaproteobacteria,2Q970@267890|Shewanellaceae 1236|Gammaproteobacteria O Peptidase family M9 N-terminal - - 3.4.24.3 ko:K01387 - - - - ko00000,ko01000,ko01002,ko02042 - - - PPC,Peptidase_M9,Peptidase_M9_N k141_24328_1 1453501.JELR01000001_gene3198 2.53e-18 84.7 COG3240@1|root,COG3240@2|Bacteria,1RCCU@1224|Proteobacteria,1S2GX@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Phospholipase lecithinase hemolysin estA GO:0003674,GO:0003824,GO:0016289,GO:0016290,GO:0016787,GO:0016788,GO:0016790,GO:0047617,GO:0052689 - ko:K12686 - - - - ko00000,ko02000,ko02044 1.B.12.8 - - Autotransporter,Lipase_GDSL k141_23269_1 997296.PB1_08107 4.44e-42 150.0 COG0551@1|root,COG0551@2|Bacteria,1UIX7@1239|Firmicutes,4ISVF@91061|Bacilli,1ZS76@1386|Bacillus 91061|Bacilli L Nuclease-related domain - - - - - - - - - - - - NERD k141_26977_1 223926.28810004 1.31e-212 593.0 COG1596@1|root,COG1596@2|Bacteria,1N7GP@1224|Proteobacteria,1RQSM@1236|Gammaproteobacteria,1XUWY@135623|Vibrionales 135623|Vibrionales M Periplasmic protein involved in polysaccharide export wza - - ko:K01991 ko02026,map02026 - - - ko00000,ko00001,ko02000 1.B.18 - - Poly_export,SLBB k141_26977_2 1280001.BAOA01000057_gene4558 1.75e-75 228.0 COG0394@1|root,COG0394@2|Bacteria,1N0DZ@1224|Proteobacteria,1S92S@1236|Gammaproteobacteria,1XXJG@135623|Vibrionales 135623|Vibrionales T Belongs to the low molecular weight phosphotyrosine protein phosphatase family wzb - 3.1.3.48 ko:K01104,ko:K20945 ko05111,map05111 - - - ko00000,ko00001,ko01000 - - - LMWPc k141_26977_3 1280001.BAOA01000057_gene4557 0.0 1065.0 COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,1MVI9@1224|Proteobacteria,1RNB0@1236|Gammaproteobacteria,1XTE5@135623|Vibrionales 135623|Vibrionales D protein involved in exopolysaccharide biosynthesis wzc - - ko:K16692 - - - - ko00000,ko01000,ko01001 - - - AAA_31,GNVR,Wzz k141_26977_4 1116375.VEJY3_23681 9.4e-264 727.0 COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,1RMEN@1236|Gammaproteobacteria,1XU7P@135623|Vibrionales 135623|Vibrionales U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - - - - - - - - - - SDF k141_13843_1 218284.CCDN010000002_gene2164 3.78e-126 371.0 COG2244@1|root,COG2244@2|Bacteria,1VRYZ@1239|Firmicutes,4HV8Z@91061|Bacilli,1ZCGG@1386|Bacillus 91061|Bacilli S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid ykvU - - - - - - - - - - - MatE,Polysacc_synt,Polysacc_synt_C k141_722_2 29581.BW37_03273 2.95e-21 103.0 COG2199@1|root,COG2203@1|root,COG3614@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,COG3614@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2VQP8@28216|Betaproteobacteria,476AA@75682|Oxalobacteraceae 28216|Betaproteobacteria T CHASE - - - - - - - - - - - - CHASE,GAF_2,GGDEF,PAS_8 k141_722_3 1515746.HR45_16165 0.0 904.0 COG2801@1|root,COG3415@1|root,COG2801@2|Bacteria,COG3415@2|Bacteria,1MWVQ@1224|Proteobacteria,1RN12@1236|Gammaproteobacteria,2QEPQ@267890|Shewanellaceae 1236|Gammaproteobacteria L PFAM Integrase catalytic region - - - - - - - - - - - - HTH_23,HTH_29,rve k141_10236_1 1279017.AQYJ01000024_gene1035 3.01e-63 198.0 COG3028@1|root,COG3028@2|Bacteria,1MZ4R@1224|Proteobacteria,1S9JJ@1236|Gammaproteobacteria,467RH@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the UPF0307 family yjgA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K09889 - - - - ko00000,ko03009 - - - DUF615 k141_16020_1 1196324.A374_16088 1.54e-24 105.0 COG0601@1|root,COG0601@2|Bacteria,1VCQ9@1239|Firmicutes,4HMZ6@91061|Bacilli 91061|Bacilli EP COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components - - - ko:K02033 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 k141_29067_1 218284.CCDN010000001_gene1014 2.12e-24 100.0 COG0491@1|root,COG0491@2|Bacteria,1TQPX@1239|Firmicutes,4HAV6@91061|Bacilli,1ZCFS@1386|Bacillus 91061|Bacilli S COG0491 Zn-dependent hydrolases, including glyoxylases yqjP - - - - - - - - - - - Lactamase_B k141_29067_2 218284.CCDN010000001_gene1015 2.99e-98 292.0 COG0300@1|root,COG0300@2|Bacteria,1TSJ3@1239|Firmicutes,4HDU5@91061|Bacilli,1ZBRZ@1386|Bacillus 91061|Bacilli S Belongs to the short-chain dehydrogenases reductases (SDR) family yqjQ - - ko:K07124 - - - - ko00000 - - - adh_short k141_13844_1 1121129.KB903368_gene773 1.15e-05 52.4 COG3209@1|root,COG3209@2|Bacteria,4NE5D@976|Bacteroidetes,2FPA4@200643|Bacteroidia,22XDX@171551|Porphyromonadaceae 976|Bacteroidetes M COG COG3209 Rhs family protein - - - - - - - - - - - - - k141_11405_1 1499680.CCFE01000024_gene2914 1.75e-13 71.6 COG0477@1|root,COG2814@2|Bacteria,1VSW8@1239|Firmicutes,4HUQC@91061|Bacilli,1ZAS8@1386|Bacillus 91061|Bacilli EGP the major facilitator superfamily bmr3 - - - - - - - - - - - MFS_1 k141_11405_2 218284.CCDN010000001_gene180 1.87e-78 241.0 COG0730@1|root,COG0730@2|Bacteria,1TQBK@1239|Firmicutes,4HBCW@91061|Bacilli,1ZCK1@1386|Bacillus 91061|Bacilli S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE k141_37369_1 1453501.JELR01000001_gene2568 2.32e-111 324.0 28P60@1|root,2ZC0V@2|Bacteria,1RC8V@1224|Proteobacteria,1S29Y@1236|Gammaproteobacteria,46714@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF4194) - - - - - - - - - - - - DUF4194 k141_37369_2 1042377.AFPJ01000016_gene147 1.01e-22 97.1 28HNB@1|root,2Z7WM@2|Bacteria,1MWQ1@1224|Proteobacteria,1RZ55@1236|Gammaproteobacteria,464IB@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_31372_14 1219076.N646_2167 4.19e-300 822.0 COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,1RNKE@1236|Gammaproteobacteria,1XTBG@135623|Vibrionales 135623|Vibrionales M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain glmU GO:0000270,GO:0000271,GO:0003674,GO:0003824,GO:0003977,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006629,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0030203,GO:0033692,GO:0034637,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509 2.3.1.157,2.7.7.23 ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00362 R00416,R05332 RC00002,RC00004,RC00166 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transf_3 k141_31372_15 1116375.VEJY3_15425 4.27e-257 708.0 COG0477@1|root,COG2814@2|Bacteria,1N196@1224|Proteobacteria,1RPMD@1236|Gammaproteobacteria,1XU5F@135623|Vibrionales 135623|Vibrionales EGP COG0477 Permeases of the major facilitator superfamily ydhC - - - - - - - - - - - MFS_1 k141_31372_16 1280001.BAOA01000052_gene1624 1.2e-206 572.0 COG0583@1|root,COG0583@2|Bacteria,1P293@1224|Proteobacteria,1RPK0@1236|Gammaproteobacteria,1XUXN@135623|Vibrionales 135623|Vibrionales K Transcriptional regulator ydhB - - - - - - - - - - - HTH_1,LysR_substrate k141_31372_17 1116375.VEJY3_15415 0.0 1001.0 COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,1RMY6@1236|Gammaproteobacteria,1XU5J@135623|Vibrionales 135623|Vibrionales E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA ilvA - 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - - PALP,Thr_dehydrat_C k141_31372_18 945550.VISI1226_17115 0.0 1182.0 COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,1RMP2@1236|Gammaproteobacteria,1XSW5@135623|Vibrionales 135623|Vibrionales H Belongs to the IlvD Edd family ilvD GO:0003674,GO:0003824,GO:0004160,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.9 ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R01209,R04441,R05070 RC00468,RC01714 ko00000,ko00001,ko00002,ko01000 - - - ILVD_EDD k141_31372_19 1116375.VEJY3_15405 9.44e-60 184.0 COG3978@1|root,COG3978@2|Bacteria,1MZ9W@1224|Proteobacteria,1S8VQ@1236|Gammaproteobacteria,1XXVG@135623|Vibrionales 135623|Vibrionales S COG3978 Acetolactate synthase (isozyme II), small (regulatory) subunit ilvM - 2.2.1.6 ko:K11258 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - ACT_5 k141_31372_20 674977.VMC_08590 0.0 1063.0 COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,1RMQQ@1236|Gammaproteobacteria,1XU32@135623|Vibrionales 135623|Vibrionales H COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase ilvG - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N k141_31372_21 1280001.BAOA01000052_gene1631 1.78e-69 223.0 COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,1RMB9@1236|Gammaproteobacteria,1XTCR@135623|Vibrionales 135623|Vibrionales O ATPase with chaperone activity comM - - ko:K07391 - - - - ko00000 - - - ChlI,Mg_chelatase,Mg_chelatase_C k141_24340_1 1121938.AUDY01000011_gene592 9.22e-107 321.0 COG0438@1|root,COG0438@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups - - - - - - - - - - - - CarboxypepD_reg,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1 k141_35141_1 349124.Hhal_2269 1.19e-09 58.9 COG0786@1|root,COG0786@2|Bacteria,1R7XT@1224|Proteobacteria,1RZ48@1236|Gammaproteobacteria 1236|Gammaproteobacteria E glutamate symporter - - - ko:K03312 - - - - ko00000,ko02000 2.A.27 - - Glt_symporter k141_35141_2 265729.GS18_0209975 4.82e-61 199.0 COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,4H9VI@91061|Bacilli,1ZB6B@1386|Bacillus 91061|Bacilli G Belongs to the GPI family pgi GO:0003674,GO:0003824,GO:0004347,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGI k141_10259_1 1294265.JCM21738_3944 5.02e-177 501.0 COG0243@1|root,COG0243@2|Bacteria,1VTS0@1239|Firmicutes,4HAZ4@91061|Bacilli,1ZBMY@1386|Bacillus 91061|Bacilli C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family fdhA - - - - - - - - - - - Molybdopterin,Molydop_binding k141_14800_2 1279017.AQYJ01000028_gene2496 1.95e-72 220.0 COG2867@1|root,COG2867@2|Bacteria,1RGUH@1224|Proteobacteria,1S61C@1236|Gammaproteobacteria,4675X@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG2867 Oligoketide cyclase lipid transport protein ratA GO:0003674,GO:0005488,GO:0006417,GO:0006446,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044877,GO:0045947,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:2000112,GO:2000113 - - - - - - - - - - Polyketide_cyc k141_2916_1 42565.FP66_00710 4.72e-171 496.0 COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,1RNA5@1236|Gammaproteobacteria,1XHZV@135619|Oceanospirillales 135619|Oceanospirillales P Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity katG - 1.11.1.21 ko:K03782 ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110 - R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906 RC00034,RC00213,RC00767,RC02141 ko00000,ko00001,ko01000 - - - peroxidase k141_30169_1 1116375.VEJY3_08315 1.43e-37 126.0 2AY4E@1|root,31Q6A@2|Bacteria,1QMUM@1224|Proteobacteria,1TK52@1236|Gammaproteobacteria,1Y232@135623|Vibrionales 1116375.VEJY3_08315|- - - - - - - - - - - - - - - - k141_30169_2 1116375.VEJY3_08320 1.35e-65 202.0 COG3602@1|root,COG3602@2|Bacteria,1MZKQ@1224|Proteobacteria,1SA68@1236|Gammaproteobacteria,1XXYN@135623|Vibrionales 135623|Vibrionales S ACT domain - - - ko:K09964 - - - - ko00000 - - - ACT_3,ACT_7 k141_30169_3 1116375.VEJY3_08325 1.76e-71 215.0 COG2824@1|root,COG2824@2|Bacteria,1RGUU@1224|Proteobacteria,1S60W@1236|Gammaproteobacteria,1XXSS@135623|Vibrionales 135623|Vibrionales P Zn-ribbon-containing protein involved in phosphonate metabolism phnA - - ko:K06193 ko01120,map01120 - - - ko00000 - - - PhnA,PhnA_Zn_Ribbon k141_33911_1 796606.BMMGA3_04570 2.17e-149 426.0 COG2761@1|root,COG2761@2|Bacteria,1TQ8K@1239|Firmicutes,4HAI8@91061|Bacilli,1ZATS@1386|Bacillus 91061|Bacilli Q dithiol-disulfide isomerase involved in polyketide biosynthesis yjbH - - - - - - - - - - - Thioredoxin_5 k141_36149_1 1294265.JCM21738_31 8.67e-84 251.0 28PNE@1|root,2ZCB6@2|Bacteria,1V214@1239|Firmicutes,4HFTI@91061|Bacilli,1ZBVY@1386|Bacillus 91061|Bacilli S Stage V sporulation protein AA spoVAA - - ko:K06403 - - - - ko00000 - - - SporV_AA k141_12680_2 314230.DSM3645_14245 1.6e-20 85.5 2BZBR@1|root,32YH6@2|Bacteria,2J41E@203682|Planctomycetes 203682|Planctomycetes - - - - - - - - - - - - - - - k141_35142_1 1279017.AQYJ01000021_gene2871 3.18e-47 160.0 COG4942@1|root,COG4942@2|Bacteria,1RD24@1224|Proteobacteria,1RR11@1236|Gammaproteobacteria,466TP@72275|Alteromonadaceae 1236|Gammaproteobacteria D COG0739 Membrane proteins related to metalloendopeptidases nlpD GO:0000920,GO:0001896,GO:0005575,GO:0005623,GO:0008150,GO:0008219,GO:0009279,GO:0009987,GO:0012501,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0043085,GO:0044093,GO:0044462,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071944 - ko:K06194,ko:K12943 - - - - ko00000 1.A.34.1.2 - - LysM,Peptidase_M23 k141_4206_2 218284.CCDN010000007_gene3808 5.52e-111 320.0 COG0629@1|root,COG0629@2|Bacteria,1V3WT@1239|Firmicutes,4HH8I@91061|Bacilli,1ZFIJ@1386|Bacillus 91061|Bacilli L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k141_25697_1 218284.CCDN010000001_gene953 9.06e-48 161.0 COG3854@1|root,COG3854@2|Bacteria,1TQ23@1239|Firmicutes,4HA2K@91061|Bacilli,1ZAWB@1386|Bacillus 91061|Bacilli S stage III sporulation protein AA spoIIIAA - - ko:K06390 - - - - ko00000 - - - AAA,T2SSE k141_25697_2 218284.CCDN010000001_gene954 3.53e-103 300.0 2CEWW@1|root,32S0Q@2|Bacteria,1VAEG@1239|Firmicutes,4HGSK@91061|Bacilli,1ZCXE@1386|Bacillus 91061|Bacilli S Stage III sporulation protein spoIIIAB - - ko:K06391 - - - - ko00000 - - - Spore_III_AB k141_25697_4 218284.CCDN010000001_gene956 1.11e-39 133.0 2CPUI@1|root,32SJW@2|Bacteria,1VA9Y@1239|Firmicutes,4HIIH@91061|Bacilli,1ZGYV@1386|Bacillus 91061|Bacilli S Stage III sporulation protein AD spoIIIAD - - ko:K06393 - - - - ko00000 - - - SpoIIIAC k141_25697_5 218284.CCDN010000001_gene957 1.03e-48 167.0 2C2CG@1|root,2Z7PW@2|Bacteria,1TQQ2@1239|Firmicutes,4H9UX@91061|Bacilli,1ZCFI@1386|Bacillus 91061|Bacilli S stage III sporulation protein AE spoIIIAE - - ko:K06394 - - - - ko00000 - - - Spore_III_AE k141_10261_1 218284.CCDN010000001_gene1458 1.56e-110 328.0 COG1960@1|root,COG1960@2|Bacteria,1UK89@1239|Firmicutes,4HAR5@91061|Bacilli,1ZE5H@1386|Bacillus 91061|Bacilli I COG1960 Acyl-CoA dehydrogenases - - 1.3.8.7 ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_18539_2 1453501.JELR01000001_gene2121 0.0 1217.0 COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,1RMXI@1236|Gammaproteobacteria,464BP@72275|Alteromonadaceae 1236|Gammaproteobacteria E Peptidase family M3 dcp - 3.4.15.5 ko:K01284 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M3 k141_7658_1 1453501.JELR01000002_gene529 1.75e-226 637.0 COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,1RMT7@1236|Gammaproteobacteria,466B9@72275|Alteromonadaceae 1236|Gammaproteobacteria S Bacterial protein of unknown function (DUF885) - - - - - - - - - - - - DUF885 k141_29085_1 42565.FP66_12385 8.1e-18 81.6 COG1012@1|root,COG1012@2|Bacteria,1MUHV@1224|Proteobacteria,1RNFN@1236|Gammaproteobacteria,1XIE7@135619|Oceanospirillales 135619|Oceanospirillales C methylmalonate-semialdehyde dehydrogenase - - 1.2.1.18,1.2.1.27 ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 M00013 R00705,R00706,R00922,R00935 RC00004,RC02723,RC02817 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_29085_2 42565.FP66_12380 4.65e-54 181.0 COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,1RP0C@1236|Gammaproteobacteria,1XHQT@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - 2.6.1.18 ko:K00822 ko00280,ko00410,ko00640,ko01100,map00280,map00410,map00640,map01100 - R00907,R04187 RC00008,RC00062,RC00160 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_3 k141_19670_1 1116375.VEJY3_19081 2.21e-172 495.0 COG2176@1|root,COG2176@2|Bacteria,1MUZD@1224|Proteobacteria,1RPGP@1236|Gammaproteobacteria,1XUHP@135623|Vibrionales 135623|Vibrionales L VRR_NUC - - - - - - - - - - - - VRR_NUC k141_35143_1 1042377.AFPJ01000045_gene2579 4.54e-95 300.0 COG4223@1|root,COG4223@2|Bacteria,1N10X@1224|Proteobacteria,1RYCQ@1236|Gammaproteobacteria,46D2D@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF1631) - - - - - - - - - - - - DUF1631 k141_21997_1 1033734.CAET01000027_gene882 1.77e-106 342.0 COG2909@1|root,COG3629@1|root,COG2909@2|Bacteria,COG3629@2|Bacteria,1UWHI@1239|Firmicutes,4HADH@91061|Bacilli,1ZE89@1386|Bacillus 91061|Bacilli KT COG2909 ATP-dependent transcriptional regulator - - - ko:K03556 - - - - ko00000,ko03000 - - - AAA_16,BTAD,TPR_12,TPR_8 k141_24342_1 1127673.GLIP_1554 4.07e-34 137.0 28HBN@1|root,2Z7NM@2|Bacteria,1NXQY@1224|Proteobacteria,1SBXN@1236|Gammaproteobacteria,46C85@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_11432_1 1033734.CAET01000001_gene3960 5.69e-18 78.6 2C7Y4@1|root,34BFK@2|Bacteria,1W0Q4@1239|Firmicutes,4HYME@91061|Bacilli,1ZJ4X@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF1292) - - - - - - - - - - - - DUF1292 k141_11432_2 218284.CCDN010000009_gene4310 4.68e-226 645.0 COG1289@1|root,COG1289@2|Bacteria,1U18W@1239|Firmicutes,4IJPB@91061|Bacilli,1ZDV7@1386|Bacillus 91061|Bacilli S Fusaric acid resistance protein-like - - - - - - - - - - - - FUSC,FUSC_2 k141_32555_3 665952.HMPREF1015_00089 8.37e-101 299.0 28J08@1|root,2Z8XG@2|Bacteria,1V177@1239|Firmicutes,4HCWC@91061|Bacilli,1ZCRV@1386|Bacillus 91061|Bacilli - - yphF - - - - - - - - - - - DUF3939 k141_14801_1 1158345.JNLL01000001_gene36 5.12e-23 102.0 COG1694@1|root,COG3541@1|root,COG1694@2|Bacteria,COG3541@2|Bacteria 2|Bacteria L Predicted nucleotidyltransferase ycgL - - ko:K07074 - - - - ko00000 - - - MazG-like,Nuc-transf k141_14801_2 218284.CCDN010000001_gene1308 2.26e-18 85.1 COG0697@1|root,COG0697@2|Bacteria,1TP7K@1239|Firmicutes,4HAH1@91061|Bacilli,1ZBEF@1386|Bacillus 91061|Bacilli EG Spore germination protein gerAA_1 - - ko:K06295 - - - - ko00000 - - - GerA k141_744_1 218284.CCDN010000005_gene3268 1.19e-148 444.0 COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HACY@91061|Bacilli,1ZB8K@1386|Bacillus 91061|Bacilli O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE clpB GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564 - ko:K03695 ko04213,map04213 - - - ko00000,ko00001,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N k141_33912_1 235909.GK0222 4.1e-80 254.0 COG0707@1|root,COG0707@2|Bacteria,1UQ6A@1239|Firmicutes,4HDYW@91061|Bacilli,1WEWW@129337|Geobacillus 91061|Bacilli M Monogalactosyldiacylglycerol (MGDG) synthase - - 2.4.1.315 ko:K03429 ko00561,ko01100,map00561,map01100 - R02689,R04377 RC00005,RC00059 ko00000,ko00001,ko01000,ko01003 - GT28 - Glyco_tran_28_C,Glycos_transf_1,MGDG_synth k141_2917_1 218284.CCDN010000008_gene4198 7.43e-117 356.0 COG1523@1|root,COG1523@2|Bacteria,1TP3M@1239|Firmicutes,4HBP5@91061|Bacilli,1ZC85@1386|Bacillus 91061|Bacilli G Belongs to the glycosyl hydrolase 13 family amyX - 3.2.1.41 ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 - R02111 - ko00000,ko00001,ko01000 - CBM48,GH13 - Alpha-amylase,CBM_48 k141_18540_1 866895.HBHAL_1057 2.17e-81 246.0 COG1658@1|root,COG1658@2|Bacteria,1V3K3@1239|Firmicutes,4HH5Y@91061|Bacilli,3NE6J@45667|Halobacillus 91061|Bacilli L Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step rnmV GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043822,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 3.1.26.8 ko:K05985 - - - - ko00000,ko01000 - - - DUF4093,Toprim,Toprim_4 k141_18540_2 1219076.N646_4207 0.000156 43.1 COG0845@1|root,COG0845@2|Bacteria,1R4F3@1224|Proteobacteria,1RSAM@1236|Gammaproteobacteria,1XTNU@135623|Vibrionales 135623|Vibrionales M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - - - - - - - - - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 k141_9182_1 1219077.VAZ01S_027_00290 0.0 1085.0 COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,1RMQI@1236|Gammaproteobacteria,1XSGU@135623|Vibrionales 135623|Vibrionales K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth rpoD - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 k141_9182_2 1116375.VEJY3_01820 0.0 1123.0 COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,1RMGA@1236|Gammaproteobacteria,1XUTH@135623|Vibrionales 135623|Vibrionales L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG - - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB_bind,DnaG_DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2 k141_9182_3 1219076.N646_2562 1.06e-81 244.0 COG1610@1|root,COG1610@2|Bacteria,1RGZS@1224|Proteobacteria,1S61A@1236|Gammaproteobacteria,1XWVI@135623|Vibrionales 135623|Vibrionales S Yqey-like protein - - - ko:K09117 - - - - ko00000 - - - YqeY k141_9182_4 1280001.BAOA01000021_gene864 2.55e-40 133.0 COG0828@1|root,COG0828@2|Bacteria,1MZCC@1224|Proteobacteria,1S8QZ@1236|Gammaproteobacteria,1XYBV@135623|Vibrionales 135623|Vibrionales J Belongs to the bacterial ribosomal protein bS21 family rpsU GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02970 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S21 k141_9182_5 1219076.N646_2564 3.8e-250 687.0 COG0533@1|root,COG0533@2|Bacteria,1MU6S@1224|Proteobacteria,1RN8M@1236|Gammaproteobacteria,1XSZ3@135623|Vibrionales 135623|Vibrionales J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction tsaD - 2.3.1.234 ko:K01409 - - R10648 RC00070,RC00416 ko00000,ko01000,ko03016 - - - Peptidase_M22 k141_16184_1 1453501.JELR01000001_gene2292 5.62e-34 129.0 COG2225@1|root,COG2225@2|Bacteria,1MVEV@1224|Proteobacteria,1RPVI@1236|Gammaproteobacteria,464G0@72275|Alteromonadaceae 1236|Gammaproteobacteria C Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA glcB GO:0000287,GO:0003674,GO:0003824,GO:0004474,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009436,GO:0009987,GO:0016054,GO:0016740,GO:0016746,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0046395,GO:0046487,GO:0046872,GO:0046912,GO:0071704,GO:0072329,GO:1901575 2.3.3.9 ko:K01638 ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200 M00012 R00472 RC00004,RC00308,RC02747 ko00000,ko00001,ko00002,ko01000 - - iECSF_1327.ECSF_2799,iECW_1372.ECW_m3242,iEKO11_1354.EKO11_0745,iWFL_1372.ECW_m3242 Malate_synthase k141_22157_1 1116375.VEJY3_15310 1.4e-229 636.0 COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,1RPJE@1236|Gammaproteobacteria,1XSI4@135623|Vibrionales 135623|Vibrionales LU Rossmann fold nucleotide-binding protein involved in DNA uptake smf - - ko:K04096 - - - - ko00000 - - - DNA_processg_A k141_22157_2 1116375.VEJY3_15305 1.85e-43 144.0 COG2922@1|root,COG2922@2|Bacteria,1RD5F@1224|Proteobacteria,1S43X@1236|Gammaproteobacteria,1XTHN@135623|Vibrionales 135623|Vibrionales S Belongs to the Smg family smg - - ko:K03747 - - - - ko00000 - - - DUF494 k141_5656_1 1453501.JELR01000002_gene563 2.54e-144 420.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPWS@1236|Gammaproteobacteria,464W9@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0488 ATPase components of ABC transporters with duplicated ATPase domains yjjK GO:0003674,GO:0003824,GO:0005488,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:2000112,GO:2000113 3.6.3.25 ko:K06020 - - - - ko00000,ko01000 - - - ABC_tran,ABC_tran_Xtn k141_24571_1 218284.CCDN010000001_gene1959 2.71e-179 514.0 COG2766@1|root,COG2766@2|Bacteria,1TRTW@1239|Firmicutes,4HA8A@91061|Bacilli,1ZBM9@1386|Bacillus 91061|Bacilli T Ser protein kinase prkA - - ko:K07180 - - - - ko00000 - - - AAA_PrkA,PrkA k141_19814_1 218284.CCDN010000001_gene1112 2.94e-94 275.0 COG0105@1|root,COG0105@2|Bacteria,1V44G@1239|Firmicutes,4HH8C@91061|Bacilli,1ZFJ7@1386|Bacillus 91061|Bacilli F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate ndk GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 M00049,M00050,M00052,M00053 R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895 RC00002 ko00000,ko00001,ko00002,ko01000,ko04131 - - - NDK k141_20871_2 1294265.JCM21738_4162 5.4e-34 121.0 COG2813@1|root,COG2813@2|Bacteria,1V1BG@1239|Firmicutes,4HHCA@91061|Bacilli,1ZBPR@1386|Bacillus 91061|Bacilli J Methyltransferase rsmC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 2.1.1.172 ko:K00564 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - MTS k141_23495_1 1294265.JCM21738_3435 1.07e-41 142.0 COG0765@1|root,COG0765@2|Bacteria,1TPM3@1239|Firmicutes,4HAS2@91061|Bacilli,1ZBUZ@1386|Bacillus 91061|Bacilli E COG0765 ABC-type amino acid transport system, permease component artQ GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015318,GO:0015711,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1903825,GO:1905039 - ko:K02029 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 k141_23495_2 1294265.JCM21738_3434 6.55e-98 290.0 COG0834@1|root,COG0834@2|Bacteria,1TT16@1239|Firmicutes,4HD16@91061|Bacilli,1ZQ0V@1386|Bacillus 91061|Bacilli ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain artP - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 k141_6759_1 1294265.JCM21738_416 3.58e-55 175.0 COG0437@1|root,COG0437@2|Bacteria,1V35R@1239|Firmicutes,4HVW5@91061|Bacilli,1ZSG7@1386|Bacillus 91061|Bacilli C 4Fe-4S dicluster domain - - - - - - - - - - - - Fer4_11 k141_6759_2 1294265.JCM21738_415 5.16e-93 286.0 COG0243@1|root,COG0243@2|Bacteria,1TPZG@1239|Firmicutes,4HBA3@91061|Bacilli,1ZEAY@1386|Bacillus 91061|Bacilli C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - 1.8.5.3 ko:K07306 ko00920,map00920 - R09501 RC02555 ko00000,ko00001,ko01000,ko02000 5.A.3.3 - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal k141_22158_1 218284.CCDN010000001_gene119 4.61e-110 325.0 COG2340@1|root,COG2340@2|Bacteria,1UYZ4@1239|Firmicutes,4HBTC@91061|Bacilli,1ZCGK@1386|Bacillus 91061|Bacilli S protein with SCP PR1 domains ylbC - - - - - - - - - - - CAP,CAP_assoc_N k141_17343_1 1126627.BAWE01000001_gene1 1.93e-40 153.0 COG2304@1|root,COG2304@2|Bacteria,1QU09@1224|Proteobacteria,2TXRZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria M COG3209 Rhs family protein - - - - - - - - - - - - - k141_14953_2 218284.CCDN010000001_gene672 1.8e-189 541.0 COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,4HACD@91061|Bacilli,1ZBXI@1386|Bacillus 91061|Bacilli J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) aspS - 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - GAD,tRNA-synt_2,tRNA_anti-codon k141_31440_1 218284.CCDN010000001_gene1814 1.36e-129 386.0 COG2508@1|root,COG2508@2|Bacteria,1TSQP@1239|Firmicutes,4HB10@91061|Bacilli,1ZBH4@1386|Bacillus 91061|Bacilli QT Purine catabolism regulatory protein-like family - - - ko:K09684 - - - - ko00000,ko03000 - - - HTH_30,PucR k141_34062_1 1136163.M565_ctg5P0646 0.000196 40.0 2BJMJ@1|root,32DZ0@2|Bacteria,1QMUC@1224|Proteobacteria,1TK4Q@1236|Gammaproteobacteria,1Y22K@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_34062_2 1116375.VEJY3_07455 4.52e-176 493.0 2CEFX@1|root,34B3J@2|Bacteria,1P0R4@1224|Proteobacteria,1SSPS@1236|Gammaproteobacteria,1XTMJ@135623|Vibrionales 135623|Vibrionales - - VPA0901 - - - - - - - - - - - - k141_874_1 1294265.JCM21738_2028 1.44e-80 239.0 COG0781@1|root,COG0781@2|Bacteria,1VA9B@1239|Firmicutes,4HKMU@91061|Bacilli,1ZH3P@1386|Bacillus 91061|Bacilli K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons nusB - - ko:K03625 - - - - ko00000,ko03009,ko03021 - - - NusB k141_874_2 1294265.JCM21738_2027 2.44e-25 100.0 COG0190@1|root,COG0190@2|Bacteria,1TP1P@1239|Firmicutes,4H9Q6@91061|Bacilli,1ZC9G@1386|Bacillus 91061|Bacilli F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate folD GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R01220,R01655 RC00202,RC00578 ko00000,ko00001,ko00002,ko01000 - - - THF_DHG_CYH,THF_DHG_CYH_C k141_6760_1 1453501.JELR01000001_gene2141 3.82e-86 275.0 COG1506@1|root,COG1506@2|Bacteria,1MUJ3@1224|Proteobacteria,1RRN4@1236|Gammaproteobacteria,465BC@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases pqqM - - - - - - - - - - - PD40,Peptidase_S9 k141_11604_1 1385511.N783_03485 2.03e-25 100.0 2DZYA@1|root,32RCQ@2|Bacteria,1UHMG@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - - k141_24572_1 218284.CCDN010000005_gene3225 1.32e-61 202.0 COG2356@1|root,COG4085@1|root,COG2356@2|Bacteria,COG4085@2|Bacteria,1U9GI@1239|Firmicutes,4IJKB@91061|Bacilli,1ZAYK@1386|Bacillus 91061|Bacilli L Ribonuclease bsn GO:0005575,GO:0005576 - - - - - - - - - - Endonuclease_1 k141_12823_1 1279017.AQYJ01000027_gene1833 1.13e-99 305.0 COG0508@1|root,COG0508@2|Bacteria,1MVDC@1224|Proteobacteria,1RQ9Y@1236|Gammaproteobacteria,4657Y@72275|Alteromonadaceae 1236|Gammaproteobacteria C 2-oxoacid dehydrogenases acyltransferase (catalytic domain) pdhC - 2.3.1.12,2.3.1.168 ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 M00036,M00307 R00209,R02569,R02662,R03174,R04097,R10998 RC00004,RC02727,RC02742,RC02857,RC02870 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding k141_12823_3 1279017.AQYJ01000027_gene1831 2.38e-173 493.0 COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,1RREX@1236|Gammaproteobacteria,4666W@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit pdhA - 1.2.4.1 ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh k141_1834_3 1265503.KB905160_gene2900 3.3e-167 474.0 COG4782@1|root,COG4782@2|Bacteria,1REVW@1224|Proteobacteria,1S55K@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Alpha/beta hydrolase of unknown function (DUF900) - - - - - - - - - - - - DUF900 k141_1834_4 1122614.JHZF01000011_gene1120 1.08e-131 389.0 COG5514@1|root,COG5514@2|Bacteria,1QEPI@1224|Proteobacteria,2V9IP@28211|Alphaproteobacteria,2PF24@252301|Oceanicola 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_1834_5 1380387.JADM01000001_gene323 2.84e-09 66.6 COG2771@1|root,COG2771@2|Bacteria,1MWC0@1224|Proteobacteria,1S42R@1236|Gammaproteobacteria,1XQW8@135619|Oceanospirillales 135619|Oceanospirillales K Regulatory protein LuxR - - - - - - - - - - - - GerE k141_27183_1 1461246.X2KPG8_9VIRU 4.94e-05 48.1 4QAXV@10239|Viruses 10239|Viruses S YopX protein - - - - - - - - - - - - - k141_27183_2 114416.Q9MC33_9CAUD 3.94e-29 114.0 4QBX9@10239|Viruses,4QWQQ@35237|dsDNA viruses no RNA stage,4QPDR@28883|Caudovirales,4QKZW@10699|Siphoviridae 10699|Siphoviridae S Rad52/22 family double-strand break repair protein - - - - - - - - - - - - - k141_5657_1 218284.CCDN010000006_gene3740 8.57e-40 140.0 COG1609@1|root,COG1609@2|Bacteria,1TPZM@1239|Firmicutes,4H9ZT@91061|Bacilli,1ZB2U@1386|Bacillus 91061|Bacilli K Transcriptional regulator malR - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_1,Peripla_BP_3 k141_22160_1 218284.CCDN010000002_gene2253 8.19e-133 381.0 COG3568@1|root,COG3568@2|Bacteria,1TQZG@1239|Firmicutes,4HGS5@91061|Bacilli,1ZQ0K@1386|Bacillus 91061|Bacilli L Endonuclease/Exonuclease/phosphatase family rgfB - 3.1.3.90 ko:K06896 ko00500,map00500 - R10486 RC00017 ko00000,ko00001,ko01000 - - - Exo_endo_phos k141_3040_1 314265.R2601_00440 5.41e-44 152.0 COG1706@1|root,COG1706@2|Bacteria,1MVKW@1224|Proteobacteria,2TQNX@28211|Alphaproteobacteria 28211|Alphaproteobacteria N Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation flgI - - - - - - - - - - - FlgI k141_3040_2 314265.R2601_00435 9.96e-26 101.0 COG0745@1|root,COG0745@2|Bacteria,1R90P@1224|Proteobacteria,2U2Q9@28211|Alphaproteobacteria 28211|Alphaproteobacteria K COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - - - - - - - - - - Trans_reg_C k141_10387_1 1116375.VEJY3_16596 7.34e-63 205.0 COG0665@1|root,COG0665@2|Bacteria,1MVGP@1224|Proteobacteria,1RNJ9@1236|Gammaproteobacteria,1XSCR@135623|Vibrionales 135623|Vibrionales E COG0665 Glycine D-amino acid oxidases (deaminating) - - - - - - - - - - - - DAO k141_10387_2 1219076.N646_3677 3.16e-42 142.0 2AWFT@1|root,31N76@2|Bacteria,1QJYI@1224|Proteobacteria,1TI0T@1236|Gammaproteobacteria,1XY3P@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF3316) - - - - - - - - - - - - DUF3316 k141_10387_3 1116375.VEJY3_16591 1.99e-175 493.0 COG0697@1|root,COG0697@2|Bacteria,1RDF6@1224|Proteobacteria,1S3F3@1236|Gammaproteobacteria,1XTBV@135623|Vibrionales 135623|Vibrionales EG of the drug metabolite transporter (DMT) superfamily - - - - - - - - - - - - EamA k141_19816_1 82996.sch_06775 6.06e-37 129.0 COG0314@1|root,COG0314@2|Bacteria,1RGUX@1224|Proteobacteria,1S5YH@1236|Gammaproteobacteria,4036Y@613|Serratia 1236|Gammaproteobacteria H Molybdopterin guanine dinucleotide biosynthesis protein MoaE moaE GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016782,GO:0016783,GO:0018130,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0030366,GO:0032324,GO:0034641,GO:0042278,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.8.1.12 ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09395 RC02507 ko00000,ko00001,ko01000 - - iAPECO1_1312.APECO1_1305,iEC042_1314.EC042_0869,iEC55989_1330.EC55989_0828,iECABU_c1320.ECABU_c08270,iECED1_1282.ECED1_0750,iECIAI1_1343.ECIAI1_0820,iECIAI39_1322.ECIAI39_0761,iECNA114_1301.ECNA114_0717,iECO103_1326.ECO103_0820,iECO111_1330.ECO111_0846,iECO26_1355.ECO26_0911,iECOK1_1307.ECOK1_0787,iECP_1309.ECP_0799,iECS88_1305.ECS88_0802,iECSE_1348.ECSE_0839,iECSF_1327.ECSF_0711,iECW_1372.ECW_m0841,iEKO11_1354.EKO11_3101,iEcE24377_1341.EcE24377A_0848,iG2583_1286.G2583_1013,iLF82_1304.LF82_1369,iNRG857_1313.NRG857_03500,iSSON_1240.SSON_0764,iUMN146_1321.UM146_13720,iUTI89_1310.UTI89_C0785,iWFL_1372.ECW_m0841,ic_1306.c0867 MoaE k141_25866_5 1279017.AQYJ01000024_gene1072 1.4e-96 285.0 COG2823@1|root,COG2823@2|Bacteria,1MUZ2@1224|Proteobacteria,1RY2B@1236|Gammaproteobacteria,467G8@72275|Alteromonadaceae 1236|Gammaproteobacteria S periplasmic or secreted lipoprotein yraP GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0032153,GO:0044462,GO:0044464,GO:0071944 - - - - - - - - - - BON k141_25866_7 1042377.AFPJ01000034_gene2352 8.31e-106 309.0 COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,1RP1N@1236|Gammaproteobacteria,464MJ@72275|Alteromonadaceae 1236|Gammaproteobacteria S LemA family lemA - - ko:K03744 - - - - ko00000 - - - LemA k141_25866_8 1279017.AQYJ01000024_gene1069 3.08e-284 797.0 COG0501@1|root,COG0501@2|Bacteria,1MVU4@1224|Proteobacteria,1RPJ5@1236|Gammaproteobacteria,46584@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG0501 Zn-dependent protease with chaperone function htpX - - ko:K03799 - M00743 - - ko00000,ko00002,ko01000,ko01002 - - - Peptidase_M48 k141_25866_10 1279017.AQYJ01000024_gene1067 7.34e-71 234.0 COG2199@1|root,COG2199@2|Bacteria,1R80Z@1224|Proteobacteria,1RZUV@1236|Gammaproteobacteria,4671H@72275|Alteromonadaceae 1236|Gammaproteobacteria T GGDEF domain yliF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - iSBO_1134.SBO_0726 GAPES2,GGDEF k141_25866_12 1453501.JELR01000001_gene3066 4.16e-143 404.0 COG0625@1|root,COG0625@2|Bacteria,1MXJD@1224|Proteobacteria,1RP12@1236|Gammaproteobacteria,464JH@72275|Alteromonadaceae 1236|Gammaproteobacteria O Glutathione S-transferase sspA GO:0001000,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0006950,GO:0008150,GO:0009605,GO:0009889,GO:0009891,GO:0009893,GO:0009991,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0042594,GO:0043175,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070063,GO:0080090,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - ko:K03599 - - - - ko00000,ko02000,ko03021 1.A.12.3.1 - - GST_C,GST_N,GST_N_3 k141_25866_13 1453501.JELR01000001_gene3067 0.0 1341.0 COG1290@1|root,COG2857@1|root,COG1290@2|Bacteria,COG2857@2|Bacteria,1MV97@1224|Proteobacteria,1RNCP@1236|Gammaproteobacteria,465NG@72275|Alteromonadaceae 1236|Gammaproteobacteria C Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis petB - - ko:K00412 ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152 - - ko00000,ko00001,ko00002,ko03029 - - - Cytochrom_B_C,Cytochrom_C1,Cytochrome_B k141_25866_16 1279017.AQYJ01000024_gene1060 6.11e-99 287.0 COG0102@1|root,COG0102@2|Bacteria,1RA11@1224|Proteobacteria,1S280@1236|Gammaproteobacteria,466GF@72275|Alteromonadaceae 1236|Gammaproteobacteria J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly rplM GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0070180,GO:0071704,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - ko:K02871 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L13 k141_25866_17 1042377.AFPJ01000034_gene2343 3.98e-204 571.0 COG1485@1|root,COG1485@2|Bacteria,1MUUW@1224|Proteobacteria,1RMTJ@1236|Gammaproteobacteria,464WH@72275|Alteromonadaceae 1236|Gammaproteobacteria D Reduces the stability of FtsZ polymers in the presence of ATP zapE GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032153,GO:0044424,GO:0044464,GO:0051301 - ko:K06916 - - - - ko00000,ko03036 - - - AFG1_ATPase k141_25866_19 1279017.AQYJ01000024_gene1056 1.27e-272 747.0 COG2046@1|root,COG2046@2|Bacteria,1MUQB@1224|Proteobacteria,1RP4Q@1236|Gammaproteobacteria,46AE3@72275|Alteromonadaceae 1236|Gammaproteobacteria P PUA-like domain sat - 2.7.7.4 ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176,M00596 R00529,R04929 RC02809,RC02889 ko00000,ko00001,ko00002,ko01000 - - - ATP-sulfurylase,PUA_2 k141_25866_20 1279017.AQYJ01000024_gene1055 4.69e-179 509.0 COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,4645J@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain degS GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009897,GO:0009986,GO:0009987,GO:0010033,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031975,GO:0033554,GO:0035966,GO:0035967,GO:0042221,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051716,GO:0051788,GO:0070011,GO:0070887,GO:0071218,GO:0071310,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0140096,GO:1901564 - ko:K04691,ko:K04772 - - - - ko00000,ko01000,ko01002 - - - PDZ_2,Trypsin_2 k141_25866_21 1453501.JELR01000001_gene3075 6.85e-46 154.0 2CD3D@1|root,32RWZ@2|Bacteria,1N61G@1224|Proteobacteria,1SB8Q@1236|Gammaproteobacteria,46BJ4@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF4440) - - - - - - - - - - - - DUF4440 k141_6784_1 218284.CCDN010000001_gene1356 1.63e-185 529.0 COG1574@1|root,COG1574@2|Bacteria,1TRB6@1239|Firmicutes,4HFBR@91061|Bacilli,1ZM5P@1386|Bacillus 91061|Bacilli S Amidohydrolase family - - - - - - - - - - - - Amidohydro_3 k141_10399_1 1453501.JELR01000002_gene911 1.5e-91 286.0 COG1716@1|root,COG3456@1|root,COG1716@2|Bacteria,COG3456@2|Bacteria,1R3R7@1224|Proteobacteria,1RRIU@1236|Gammaproteobacteria,46CUW@72275|Alteromonadaceae 1236|Gammaproteobacteria T Forkhead associated domain - - - ko:K07169,ko:K11894,ko:K11913 ko02025,ko03070,map02025,map03070 - - - ko00000,ko00001,ko02044 3.A.23.1 - - FHA k141_30314_1 1279017.AQYJ01000029_gene3745 1.49e-80 261.0 COG3568@1|root,COG3568@2|Bacteria,1R977@1224|Proteobacteria,1RTF2@1236|Gammaproteobacteria,466AF@72275|Alteromonadaceae 1236|Gammaproteobacteria L Type I phosphodiesterase / nucleotide pyrophosphatase - - - - - - - - - - - - Exo_endo_phos,Phosphodiest k141_14962_1 935837.JAEK01000067_gene3082 6.05e-100 301.0 COG1653@1|root,COG1653@2|Bacteria,1UY14@1239|Firmicutes,4HEMF@91061|Bacilli,1ZQ33@1386|Bacillus 91061|Bacilli G COG1653 ABC-type sugar transport system, periplasmic component yurO - - ko:K10117 ko02010,map02010 M00196 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.28 - - SBP_bac_1,SBP_bac_8 k141_27212_1 477974.Daud_1172 5.03e-19 88.2 COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,2493T@186801|Clostridia,2602V@186807|Peptococcaceae 186801|Clostridia S GTPase that plays an essential role in the late steps of ribosome biogenesis der - - ko:K03977 - - - - ko00000,ko03009 - - - KH_dom-like,MMR_HSR1 k141_27212_2 1320556.AVBP01000011_gene3394 8.48e-15 72.4 COG0344@1|root,COG0344@2|Bacteria,1NKK8@1224|Proteobacteria,2TQXK@28211|Alphaproteobacteria 28211|Alphaproteobacteria I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP - - 2.3.1.15 ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - G3P_acyltransf k141_12841_1 1116375.VEJY3_21771 1.17e-73 231.0 COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,1RP4D@1236|Gammaproteobacteria,1XW5K@135623|Vibrionales 135623|Vibrionales E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine - - 4.2.1.20 ko:K06001 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - PALP k141_12841_2 1280001.BAOA01000058_gene4607 4.19e-44 144.0 2DE9N@1|root,32U2Y@2|Bacteria,1N2CJ@1224|Proteobacteria,1SA7J@1236|Gammaproteobacteria,1XYJW@135623|Vibrionales 135623|Vibrionales - - VPA0586 - - - - - - - - - - - - k141_12841_3 1116375.VEJY3_21761 1.92e-127 365.0 COG2039@1|root,COG2039@2|Bacteria,1MWYG@1224|Proteobacteria,1RPYK@1236|Gammaproteobacteria,1XVAR@135623|Vibrionales 135623|Vibrionales O Removes 5-oxoproline from various penultimate amino acid residues except L-proline pcp - 3.4.19.3 ko:K01304 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C15 k141_12841_4 1116375.VEJY3_21756 2.11e-223 617.0 COG0523@1|root,COG0523@2|Bacteria,1MVZV@1224|Proteobacteria,1RPKP@1236|Gammaproteobacteria,1XSPY@135623|Vibrionales 135623|Vibrionales S GTPases (G3E family) - - - - - - - - - - - - cobW k141_24599_1 218284.CCDN010000006_gene3710 1.57e-16 77.0 COG0697@1|root,COG0697@2|Bacteria,1UYSM@1239|Firmicutes,4HFBU@91061|Bacilli,1ZAQS@1386|Bacillus 91061|Bacilli EG EamA-like transporter family yoaV5 - - - - - - - - - - - EamA k141_24599_2 218284.CCDN010000006_gene3712 4.42e-41 142.0 COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,4HAD8@91061|Bacilli,1ZC3F@1386|Bacillus 91061|Bacilli M cell wall formation murB GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008762,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0055114,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 1.3.1.98 ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R03191,R03192 RC02639 ko00000,ko00001,ko01000,ko01011 - - - FAD_binding_4,MurB_C k141_5678_1 297246.lpp1479 1.74e-10 61.6 COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,1JE3Q@118969|Legionellales 118969|Legionellales NU Type II secretion system (T2SS), protein E, N-terminal domain pilB - - ko:K02652 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE,T2SSE_N k141_5678_2 84531.JMTZ01000021_gene3849 1.14e-28 115.0 COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RNV0@1236|Gammaproteobacteria,1X49V@135614|Xanthomonadales 135614|Xanthomonadales U Type II secretory pathway pilC - - ko:K02653 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSF k141_9215_1 1279017.AQYJ01000021_gene2870 2.49e-113 334.0 COG2035@1|root,COG2035@2|Bacteria,1MXVI@1224|Proteobacteria,1RN4B@1236|Gammaproteobacteria,466EX@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF368) - - - ko:K08974 - - - - ko00000 - - - DUF368 k141_9215_2 1279017.AQYJ01000021_gene2869 1.71e-124 358.0 COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,1RMHZ@1236|Gammaproteobacteria,465SD@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins pcm GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0030091,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 ko:K00573 - - - - ko00000,ko01000 - - - PCMT k141_9215_3 1279017.AQYJ01000021_gene2868 1.71e-161 460.0 COG0585@1|root,COG0585@2|Bacteria,1MXHD@1224|Proteobacteria,1RPRF@1236|Gammaproteobacteria,465C2@72275|Alteromonadaceae 1236|Gammaproteobacteria J Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs truD GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 ko:K06176 - - - - ko00000,ko01000,ko03016 - - - TruD k141_9215_4 645991.Sgly_0301 1.46e-16 75.9 COG0245@1|root,COG0245@2|Bacteria,1V3P0@1239|Firmicutes,24HCM@186801|Clostridia,261W6@186807|Peptococcaceae 186801|Clostridia I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) ispF - 2.7.7.60,4.6.1.12 ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05633,R05637 RC00002,RC01440 ko00000,ko00001,ko00002,ko01000 - - - IspD,YgbB k141_18806_1 1307436.PBF_10082 1.99e-72 227.0 COG2186@1|root,COG2186@2|Bacteria,1V2TU@1239|Firmicutes,4HDHI@91061|Bacilli,1ZD1T@1386|Bacillus 91061|Bacilli K COG2186 Transcriptional regulators - - - ko:K05799 - - - - ko00000,ko03000 - - - FCD,GntR k141_14120_1 342113.DM82_4277 1.08e-69 230.0 COG1473@1|root,COG1473@2|Bacteria,1MUIV@1224|Proteobacteria,2VIS0@28216|Betaproteobacteria,1K085@119060|Burkholderiaceae 28216|Betaproteobacteria S amidohydrolase - - 3.5.1.32 ko:K01451 ko00360,map00360 - R01424 RC00096,RC00162 ko00000,ko00001,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 k141_14963_1 674977.VMC_22690 4.98e-154 441.0 COG1249@1|root,COG1249@2|Bacteria,1MU2Z@1224|Proteobacteria,1RMC0@1236|Gammaproteobacteria,1XTC6@135623|Vibrionales 135623|Vibrionales C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family gor - 1.8.1.7 ko:K00383 ko00480,ko04918,map00480,map04918 - R00094,R00115 RC00011 ko00000,ko00001,ko01000 - - - Pyr_redox_2,Pyr_redox_dim k141_9216_1 1442599.JAAN01000015_gene3253 1.26e-75 231.0 COG1230@1|root,COG1230@2|Bacteria,1MUSS@1224|Proteobacteria,1RQ3M@1236|Gammaproteobacteria,1X4CW@135614|Xanthomonadales 135614|Xanthomonadales P Co Zn Cd efflux system component - - - - - - - - - - - - Cation_efflux k141_14121_1 1453501.JELR01000001_gene2373 5.57e-21 92.8 COG1629@1|root,COG4771@2|Bacteria,1N6JG@1224|Proteobacteria,1RP10@1236|Gammaproteobacteria,465FE@72275|Alteromonadaceae 1236|Gammaproteobacteria P Carboxypeptidase regulatory-like domain - - - - - - - - - - - - CarboxypepD_reg,Plug,TonB_dep_Rec k141_16208_1 218284.CCDN010000008_gene4247 4.9e-205 593.0 COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H9SA@91061|Bacilli,1ZD7B@1386|Bacillus 91061|Bacilli M COG0744 Membrane carboxypeptidase (penicillin-binding protein) pbp1B - 2.4.1.129 ko:K03693,ko:K12551 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase k141_11620_1 1116375.VEJY3_07965 7.18e-191 537.0 COG0842@1|root,COG0842@2|Bacteria,1MXKS@1224|Proteobacteria,1S2NW@1236|Gammaproteobacteria,1XT6T@135623|Vibrionales 135623|Vibrionales V ABC-type multidrug transport system, permease component - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 k141_11620_2 223926.28806706 3.57e-214 593.0 COG1566@1|root,COG1566@2|Bacteria,1MXZV@1224|Proteobacteria,1S2IJ@1236|Gammaproteobacteria,1XTS4@135623|Vibrionales 135623|Vibrionales V COG0845 Membrane-fusion protein - - - ko:K01993 - - - - ko00000 - - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 k141_11620_3 223926.28806705 1.11e-281 776.0 COG1538@1|root,COG1538@2|Bacteria,1R96K@1224|Proteobacteria,1SYID@1236|Gammaproteobacteria,1XT6F@135623|Vibrionales 135623|Vibrionales MU COG1538 Outer membrane protein - - - - - - - - - - - - OEP k141_11620_4 1116375.VEJY3_07950 1.27e-44 144.0 2B5HC@1|root,31YC1@2|Bacteria,1QKAU@1224|Proteobacteria,1TIEB@1236|Gammaproteobacteria,1XYZ4@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_11620_5 1116375.VEJY3_07945 0.0 946.0 COG3290@1|root,COG3290@2|Bacteria,1MXQ5@1224|Proteobacteria,1RNRF@1236|Gammaproteobacteria,1XSAU@135623|Vibrionales 135623|Vibrionales T COG3290 Signal transduction histidine kinase regulating citrate malate metabolism - - 2.7.13.3 ko:K02476 - - - - ko00000,ko01000,ko01001,ko02022 - - - HATPase_c,HATPase_c_5,PAS,SPOB_a,sCache_3_2 k141_11620_6 223926.28806703 8.76e-138 392.0 COG4565@1|root,COG4565@2|Bacteria,1RKMA@1224|Proteobacteria,1S70V@1236|Gammaproteobacteria,1XSB3@135623|Vibrionales 135623|Vibrionales K transcriptional regulatory protein citB - - ko:K02475,ko:K07702 ko02020,map02020 M00486 - - ko00000,ko00001,ko00002,ko02022 - - - CitT,HTH_11,Response_reg k141_20111_13 223926.28806993 3.74e-77 233.0 COG0454@1|root,COG0456@2|Bacteria,1QTYD@1224|Proteobacteria,1T1S0@1236|Gammaproteobacteria,1XXXR@135623|Vibrionales 135623|Vibrionales K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10 k141_20111_14 1280001.BAOA01000034_gene2211 8.11e-72 221.0 COG1670@1|root,COG1670@2|Bacteria,1N6XN@1224|Proteobacteria,1TI7J@1236|Gammaproteobacteria,1XYJX@135623|Vibrionales 135623|Vibrionales J Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_3 k141_13015_1 218284.CCDN010000001_gene172 2.31e-102 304.0 COG0714@1|root,COG0714@2|Bacteria,1TPKR@1239|Firmicutes,4HC0K@91061|Bacilli,1ZD2B@1386|Bacillus 91061|Bacilli S ATPase family associated with various cellular activities (AAA) - - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 k141_16440_1 1453501.JELR01000005_gene1577 3.06e-141 430.0 COG1629@1|root,COG1629@2|Bacteria,1MV8W@1224|Proteobacteria,1RQEQ@1236|Gammaproteobacteria,46A77@72275|Alteromonadaceae 1236|Gammaproteobacteria P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec k141_16440_2 225849.swp_1630 1.07e-21 94.0 COG0665@1|root,COG0665@2|Bacteria,1MU40@1224|Proteobacteria,1RMJY@1236|Gammaproteobacteria,2QAJQ@267890|Shewanellaceae 1236|Gammaproteobacteria E PFAM tryptophan halogenase prnA - 1.14.19.9 ko:K14266 ko00404,ko01130,map00404,map01130 M00789,M00790 R09570 RC00949 ko00000,ko00001,ko00002,ko01000 - - - Trp_halogenase k141_29521_1 218284.CCDN010000002_gene2863 4.06e-13 64.3 29S9H@1|root,30DE0@2|Bacteria,1UB6N@1239|Firmicutes,4IMJC@91061|Bacilli,1ZKA9@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_10522_1 1294265.JCM21738_1643 4.19e-24 94.7 COG0546@1|root,COG0546@2|Bacteria,1V3DR@1239|Firmicutes,4HGMU@91061|Bacilli,1ZG6G@1386|Bacillus 91061|Bacilli S Haloacid dehalogenase-like hydrolase yjcF - - - - - - - - - - - HAD_2 k141_10522_2 1294265.JCM21738_1644 2.98e-113 335.0 COG3705@1|root,COG3705@2|Bacteria,1TPZZ@1239|Firmicutes,4HBBA@91061|Bacilli,1ZB4H@1386|Bacillus 91061|Bacilli E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine hisZ - - ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002 - - - tRNA-synt_His k141_37711_1 1403313.AXBR01000017_gene3821 1.78e-65 215.0 COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,4HAJM@91061|Bacilli,1ZD95@1386|Bacillus 91061|Bacilli P ABC transporter, ATP-binding protein ykoD GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0008150,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085 - ko:K16786,ko:K16787 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran,DUF3744 k141_5883_1 218284.CCDN010000001_gene1687 1.68e-62 194.0 COG2318@1|root,COG2318@2|Bacteria,1V8A0@1239|Firmicutes,4HIW8@91061|Bacilli,1ZR7U@1386|Bacillus 91061|Bacilli S DinB superfamily yuaE - - - - - - - - - - - DinB_2 k141_22554_2 566466.NOR53_3292 4.14e-188 552.0 COG1226@1|root,COG1226@2|Bacteria,1R7UB@1224|Proteobacteria,1S0GD@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Ryanodine receptor Ryr - - - - - - - - - - - - RyR,TrkA_N k141_1141_1 398511.BpOF4_15580 2.65e-49 168.0 COG0438@1|root,COG0438@2|Bacteria,1TPS8@1239|Firmicutes,4HA43@91061|Bacilli,1ZASJ@1386|Bacillus 91061|Bacilli M N-acetyl-alpha-D-glucosaminyl L-malate synthase bshA GO:0003674,GO:0003824,GO:0016740,GO:0016757 - ko:K00754 - - - - ko00000,ko01000 - GT4 - Glyco_transf_4,Glycos_transf_1 k141_1141_2 218284.CCDN010000001_gene1136 1.87e-170 489.0 COG0617@1|root,COG0617@2|Bacteria,1TQ2A@1239|Firmicutes,4HB2W@91061|Bacilli,1ZC20@1386|Bacillus 91061|Bacilli J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate cca - 2.7.7.72 ko:K00974 ko03013,map03013 - R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016 - - - PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2 k141_20112_1 1294265.JCM21738_200 1.37e-134 392.0 COG0017@1|root,COG0017@2|Bacteria,1TP38@1239|Firmicutes,4H9YH@91061|Bacilli,1ZC51@1386|Bacillus 91061|Bacilli J asparaginyl-tRNA asnS GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.22 ko:K01893 ko00970,map00970 M00359,M00360 R03648 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2,tRNA_anti-codon k141_17529_1 1410628.JNKS01000005_gene1224 7.31e-29 114.0 COG1974@1|root,COG1974@2|Bacteria,1TQ3H@1239|Firmicutes,24AXJ@186801|Clostridia,27IMM@186928|unclassified Lachnospiraceae 186801|Clostridia K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair lexA - 3.4.21.88 ko:K01356 - M00729 - - ko00000,ko00002,ko01000,ko01002,ko03400 - - - LexA_DNA_bind,Peptidase_S24 k141_5884_2 179408.Osc7112_4217 1.26e-09 62.0 COG1994@1|root,COG1994@2|Bacteria,1G247@1117|Cyanobacteria,1H8MK@1150|Oscillatoriales 1117|Cyanobacteria S PFAM Peptidase family M50 - - - - - - - - - - - - Peptidase_M50 k141_20113_1 1453501.JELR01000001_gene2374 1.47e-47 171.0 COG0642@1|root,COG0784@1|root,COG0642@2|Bacteria,COG0784@2|Bacteria,1R4TJ@1224|Proteobacteria,1RQKQ@1236|Gammaproteobacteria,4671J@72275|Alteromonadaceae 1236|Gammaproteobacteria T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,Response_reg k141_21069_1 1121374.KB891591_gene3473 2.37e-64 221.0 COG1629@1|root,COG4771@2|Bacteria,1MVFB@1224|Proteobacteria,1RNMS@1236|Gammaproteobacteria 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec k141_21069_3 1042377.AFPJ01000043_gene883 9.29e-180 514.0 COG0477@1|root,COG2814@2|Bacteria,1QKNX@1224|Proteobacteria,1RXRI@1236|Gammaproteobacteria,46723@72275|Alteromonadaceae 1236|Gammaproteobacteria EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 k141_24809_1 218284.CCDN010000005_gene3242 1.79e-27 109.0 COG1233@1|root,COG1233@2|Bacteria,1TRN1@1239|Firmicutes,4HA5W@91061|Bacilli,1ZDED@1386|Bacillus 91061|Bacilli Q Flavin containing amine oxidoreductase - - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 ko:K10027 ko00906,ko01100,ko01110,map00906,map01100,map01110 - R04787,R04798,R04800,R09691,R09692 RC01214,RC02088,RC02605 ko00000,ko00001,ko01000 - - - Amino_oxidase k141_24809_2 218284.CCDN010000005_gene3241 1.96e-251 697.0 COG1233@1|root,COG1233@2|Bacteria,1TS4A@1239|Firmicutes,4HB9J@91061|Bacilli,1ZCTK@1386|Bacillus 91061|Bacilli Q COG1233 Phytoene dehydrogenase and related proteins - - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 ko:K10027 ko00906,ko01100,ko01110,map00906,map01100,map01110 - R04787,R04798,R04800,R09691,R09692 RC01214,RC02088,RC02605 ko00000,ko00001,ko01000 - - - Amino_oxidase k141_28131_2 1453501.JELR01000001_gene3260 2.91e-144 421.0 COG0845@1|root,COG0845@2|Bacteria,1MVFN@1224|Proteobacteria,1RNN6@1236|Gammaproteobacteria,466K4@72275|Alteromonadaceae 1236|Gammaproteobacteria M Biotin-lipoyl like - - - ko:K18990 - M00720 - - ko00000,ko00002,ko02000 2.A.6.2.30,8.A.1 - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 k141_2051_1 1453501.JELR01000001_gene2315 2.25e-102 319.0 COG2366@1|root,COG2366@2|Bacteria,1MVMH@1224|Proteobacteria,1RPRP@1236|Gammaproteobacteria,464U8@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG2366 Protein related to penicillin acylase quiP - 3.5.1.11,3.5.1.97 ko:K01434,ko:K07116 ko00311,ko01130,map00311,map01130 - R02170 RC00166,RC00328 ko00000,ko00001,ko01000,ko01002 - - - Penicil_amidase k141_22556_1 1453501.JELR01000002_gene1142 1.71e-63 200.0 COG1349@1|root,COG1349@2|Bacteria,1MUJG@1224|Proteobacteria,1RNW4@1236|Gammaproteobacteria,465X4@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG1349 Transcriptional regulators of sugar metabolism glmR - - - - - - - - - - - DeoRC,HTH_DeoR k141_16442_1 1042377.AFPJ01000007_gene1925 1.69e-79 260.0 COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,1T4K6@1236|Gammaproteobacteria,46DC0@72275|Alteromonadaceae 1236|Gammaproteobacteria KLT Sulfatase-modifying factor enzyme 1 ppkA - 2.7.11.1 ko:K11912 ko02025,ko03070,map02025,map03070 - - - ko00000,ko00001,ko01000,ko01001,ko02044 - - - FGE-sulfatase,PEGA,Pkinase k141_5885_1 714961.BFZC1_00110 3.98e-92 282.0 COG0477@1|root,COG2814@2|Bacteria,1TRUT@1239|Firmicutes,4HCQ8@91061|Bacilli 91061|Bacilli EGP Transmembrane secretion effector - - - - - - - - - - - - MFS_1,MFS_3 k141_22557_1 218284.CCDN010000001_gene1938 3.89e-86 270.0 COG4987@1|root,COG4987@2|Bacteria,1UHN5@1239|Firmicutes,4HAAB@91061|Bacilli,1ZCKI@1386|Bacillus 91061|Bacilli V ATP-binding protein cydC - - ko:K16012 ko02010,map02010 - - - ko00000,ko00001,ko02000 3.A.1.129 - - ABC_membrane,ABC_tran k141_20114_1 218284.CCDN010000002_gene2819 2.1e-128 375.0 COG0577@1|root,COG0577@2|Bacteria,1TWFZ@1239|Firmicutes,4H9RQ@91061|Bacilli,1ZCYR@1386|Bacillus 91061|Bacilli V FtsX-like permease family hrtB GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02004,ko:K09813 ko02010,map02010 M00257,M00258 - - ko00000,ko00001,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD k141_17530_1 1117314.PCIT_16935 6.51e-179 509.0 COG0381@1|root,COG0381@2|Bacteria,1MWZN@1224|Proteobacteria,1RPNC@1236|Gammaproteobacteria,2Q19U@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria M Belongs to the UDP-N-acetylglucosamine 2-epimerase family wecB GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0008761,GO:0009058,GO:0009059,GO:0009246,GO:0009987,GO:0016051,GO:0016853,GO:0016854,GO:0016857,GO:0033692,GO:0034637,GO:0034645,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046378,GO:0071704,GO:1901135,GO:1901137,GO:1901576 3.2.1.183,5.1.3.14 ko:K01791,ko:K08068 ko00520,ko01100,ko05111,map00520,map01100,map05111 M00362 R00420 RC00290 ko00000,ko00001,ko00002,ko01000,ko01005 - - iECOK1_1307.ECOK1_4232,iECS88_1305.ECS88_4208,iECs_1301.ECs4719,iEcSMS35_1347.EcSMS35_4150,iG2583_1286.G2583_4580,iPC815.YPO3864,iSDY_1059.SDY_3962,iSSON_1240.SSON_3958,iUMN146_1321.UM146_19070,iZ_1308.Z5297 Epimerase_2 k141_24812_1 218284.CCDN010000002_gene2664 1.33e-95 285.0 COG0701@1|root,COG0701@2|Bacteria,1TQC7@1239|Firmicutes,4HDIZ@91061|Bacilli,1ZDAK@1386|Bacillus 91061|Bacilli S Predicted permease - - - ko:K07089 - - - - ko00000 - - - ArsP_1 k141_4519_1 218284.CCDN010000002_gene2009 1.03e-213 619.0 COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,4HABE@91061|Bacilli,1ZPZA@1386|Bacillus 91061|Bacilli EF Carbamoyl-phosphate synthetase ammonia chain carB GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS k141_13017_1 1453501.JELR01000002_gene412 6.48e-49 159.0 2DEP1@1|root,32U3R@2|Bacteria,1N4PQ@1224|Proteobacteria,1SBR1@1236|Gammaproteobacteria,46DMT@72275|Alteromonadaceae 1236|Gammaproteobacteria S Type VIII secretion system (T8SS), CsgF protein csgF GO:0005575,GO:0005623,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0019867,GO:0022610,GO:0030312,GO:0030313,GO:0031975,GO:0042710,GO:0044010,GO:0044462,GO:0044464,GO:0044764,GO:0051704,GO:0071944 - ko:K04338 - - - - ko00000,ko02044 - - - CsgF k141_13017_2 1042377.AFPJ01000051_gene40 4.46e-78 235.0 2C2E6@1|root,2ZPXX@2|Bacteria,1N6U8@1224|Proteobacteria,1SEU1@1236|Gammaproteobacteria 1236|Gammaproteobacteria S assembly protein CsgE csgE - - ko:K04337 - - - - ko00000,ko02044 - - - CsgE k141_13017_3 1042377.AFPJ01000051_gene39 6.71e-113 327.0 COG2197@1|root,COG2197@2|Bacteria,1NI3Z@1224|Proteobacteria,1SJ39@1236|Gammaproteobacteria 1236|Gammaproteobacteria KT helix_turn_helix, Lux Regulon - - - ko:K04333 ko02026,map02026 - - - ko00000,ko00001,ko03000 - - - GerE k141_28132_1 218284.CCDN010000002_gene2161 3.81e-38 138.0 COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4H9KU@91061|Bacilli,1ZBF2@1386|Bacillus 91061|Bacilli G Belongs to the glycosyl hydrolase 1 family bglA7 - 3.2.1.21 ko:K05350 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 - R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - - - Glyco_hydro_1 k141_28132_2 218284.CCDN010000002_gene2162 5.24e-166 474.0 COG5520@1|root,COG5520@2|Bacteria,1TS99@1239|Firmicutes,4HEUA@91061|Bacilli,1ZF3X@1386|Bacillus 91061|Bacilli M Belongs to the glycosyl hydrolase 30 family - - 3.2.1.45 ko:K01201 ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142 - R01498 RC00059,RC00451 ko00000,ko00001,ko01000 - GH30 - Glyco_hydro_30,Glyco_hydro_30C k141_20116_1 218284.CCDN010000001_gene1778 4.66e-62 195.0 2C55I@1|root,32W42@2|Bacteria,1VD5J@1239|Firmicutes,4HMAT@91061|Bacilli,1ZGJA@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_21071_1 1453501.JELR01000002_gene535 3.81e-156 446.0 COG1162@1|root,COG1162@2|Bacteria,1MUEF@1224|Proteobacteria,1RMMB@1236|Gammaproteobacteria,465K2@72275|Alteromonadaceae 1236|Gammaproteobacteria S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit rsgA2 - 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 - R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 - - - RsgA_GTPase k141_5886_1 561229.Dd1591_1049 1.39e-167 501.0 COG3408@1|root,COG3408@2|Bacteria,1NJCP@1224|Proteobacteria,1RXM5@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Bacterial alpha-L-rhamnosidase C-terminal domain - - 3.2.1.40 ko:K05989 - - - - ko00000,ko01000 - - - Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N k141_26144_2 491952.Mar181_2520 5.21e-187 530.0 COG0624@1|root,COG0624@2|Bacteria,1MVBR@1224|Proteobacteria,1RNDG@1236|Gammaproteobacteria,1XP1A@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the peptidase M20A family. ArgE subfamily - - 3.5.1.16 ko:K01438 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R00669,R09107 RC00064,RC00300 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20 k141_22560_2 218284.CCDN010000005_gene3494 2.38e-70 220.0 COG1105@1|root,COG1105@2|Bacteria,1TQ36@1239|Firmicutes,4HANU@91061|Bacilli,1ZB76@1386|Bacillus 91061|Bacilli G Belongs to the carbohydrate kinase PfkB family pfkB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046835,GO:0071704 2.7.1.56 ko:K00882 ko00051,map00051 - R02071 RC00002,RC00017 ko00000,ko00001,ko01000 - - iYO844.BSU14390 PfkB k141_11880_1 1279017.AQYJ01000025_gene687 2.86e-234 674.0 COG1026@1|root,COG1026@2|Bacteria,1MVDJ@1224|Proteobacteria,1RYNI@1236|Gammaproteobacteria,465V1@72275|Alteromonadaceae 1236|Gammaproteobacteria S Zn-dependent peptidases, insulinase-like - - - ko:K06972 - - - - ko00000,ko01000,ko01002 - - - M16C_assoc,Peptidase_M16,Peptidase_M16_C k141_35602_1 1117647.M5M_07715 1.05e-141 415.0 COG0477@1|root,COG2814@2|Bacteria,1QKNX@1224|Proteobacteria,1RSAI@1236|Gammaproteobacteria 1236|Gammaproteobacteria EGP Major Facilitator - - - - - - - - - - - - MFS_1 k141_35602_2 1042377.AFPJ01000036_gene1132 1.59e-267 763.0 COG0308@1|root,COG0308@2|Bacteria,1MUV3@1224|Proteobacteria,1RS0E@1236|Gammaproteobacteria,4666I@72275|Alteromonadaceae 1236|Gammaproteobacteria E Peptidase family M1 domain - - - - - - - - - - - - Peptidase_M1 k141_29557_2 1323663.AROI01000024_gene1549 6.53e-51 168.0 COG0600@1|root,COG0600@2|Bacteria,1MVAE@1224|Proteobacteria,1RPEN@1236|Gammaproteobacteria 1236|Gammaproteobacteria P ABC-type nitrate sulfonate bicarbonate transport system permease component - - - ko:K02050 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - BPD_transp_1 k141_22589_1 1227360.C176_07907 2.25e-46 158.0 COG3393@1|root,COG3393@2|Bacteria,1V9KV@1239|Firmicutes,4HJ79@91061|Bacilli,26HFA@186818|Planococcaceae 91061|Bacilli S GNAT acetyltransferase - - - - - - - - - - - - GNAT_acetyltran k141_22589_2 218284.CCDN010000001_gene279 2.16e-74 228.0 COG1670@1|root,COG1670@2|Bacteria,1V3EY@1239|Firmicutes,4HGKG@91061|Bacilli,1ZG8B@1386|Bacillus 91061|Bacilli J Benzoate transporter - - - - - - - - - - - - Acetyltransf_1 k141_1168_2 379731.PST_1747 2.64e-77 243.0 COG0621@1|root,COG0621@2|Bacteria,1MU7N@1224|Proteobacteria,1RN46@1236|Gammaproteobacteria,1Z0RS@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria J Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 rimO GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016782,GO:0018193,GO:0018197,GO:0018198,GO:0018339,GO:0019538,GO:0035596,GO:0035599,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901564 2.8.4.4 ko:K14441 - - R10652 RC00003,RC03217 ko00000,ko01000,ko03009 - - - Radical_SAM,TRAM,UPF0004 k141_17564_1 1453501.JELR01000001_gene2576 3.52e-105 307.0 COG0288@1|root,COG0288@2|Bacteria,1MV1U@1224|Proteobacteria,1SYDI@1236|Gammaproteobacteria,464WD@72275|Alteromonadaceae 1236|Gammaproteobacteria P Reversible hydration of carbon dioxide cynT GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009439,GO:0009440,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0034641,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0071704,GO:1901564,GO:1901565,GO:1901575 4.2.1.1 ko:K01673 ko00910,map00910 - R00132,R10092 RC02807 ko00000,ko00001,ko01000 - - iJN746.PP_0100 Pro_CA k141_36449_1 218284.CCDN010000002_gene2867 1.69e-35 136.0 COG1858@1|root,COG3391@1|root,COG1858@2|Bacteria,COG3391@2|Bacteria,1V255@1239|Firmicutes,4HEF2@91061|Bacilli,1ZPVH@1386|Bacillus 91061|Bacilli P Lactonase, 7-bladed beta-propeller - - - - - - - - - - - - Cytochrom_D1,DHOR,Lactonase k141_36449_2 218284.CCDN010000002_gene2866 1.26e-92 290.0 COG1331@1|root,COG1331@2|Bacteria,1U9D9@1239|Firmicutes,4HD6V@91061|Bacilli,1ZF58@1386|Bacillus 91061|Bacilli O Highly conserved protein containing a thioredoxin domain - - - - - - - - - - - - - k141_35625_2 1116375.VEJY3_01840 2.36e-180 503.0 COG0596@1|root,COG0596@2|Bacteria,1QTTN@1224|Proteobacteria,1RZJX@1236|Gammaproteobacteria,1Y2F9@135623|Vibrionales 135623|Vibrionales S Ndr family - - - - - - - - - - - - Abhydrolase_1 k141_35625_3 223926.28805393 1.29e-132 377.0 COG0344@1|root,COG0344@2|Bacteria,1RD4Z@1224|Proteobacteria,1RN1J@1236|Gammaproteobacteria,1XT3Z@135623|Vibrionales 135623|Vibrionales I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP plsY - 2.3.1.15 ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - G3P_acyltransf k141_35625_4 223926.28805394 1.34e-74 225.0 COG1539@1|root,COG1539@2|Bacteria,1MZ8Z@1224|Proteobacteria,1S9B2@1236|Gammaproteobacteria,1XXCM@135623|Vibrionales 135623|Vibrionales H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin folB - 1.13.11.81,4.1.2.25,5.1.99.8 ko:K01633 ko00790,ko01100,map00790,map01100 M00126,M00840 R03504,R11037,R11073 RC00721,RC00943,RC01479,RC03333,RC03334 ko00000,ko00001,ko00002,ko01000 - - - FolB k141_35625_5 223926.28805395 1.96e-102 297.0 COG0801@1|root,COG0801@2|Bacteria,1RHNN@1224|Proteobacteria,1S62M@1236|Gammaproteobacteria,1XXCH@135623|Vibrionales 135623|Vibrionales H COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase folK-1 - 2.7.6.3 ko:K00950 ko00790,ko01100,map00790,map01100 M00126,M00841 R03503 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - HPPK k141_35625_6 1219076.N646_2569 1.12e-176 494.0 COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,1RQQT@1236|Gammaproteobacteria,1XSIU@135623|Vibrionales 135623|Vibrionales V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin uppP - 3.6.1.27 ko:K06153 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - BacA k141_35625_7 1219076.N646_2570 3.23e-28 110.0 COG0617@1|root,COG0617@2|Bacteria,1MU2X@1224|Proteobacteria,1RPFJ@1236|Gammaproteobacteria,1XT9B@135623|Vibrionales 135623|Vibrionales F Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases cca GO:0003674,GO:0003824,GO:0004652,GO:0004810,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0070566,GO:0071704,GO:0090304,GO:1901360,GO:1990817 2.7.7.72 ko:K00974 ko03013,map03013 - R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016 - - - HD,PolyA_pol,PolyA_pol_RNAbd k141_20144_1 399739.Pmen_0003 1.22e-11 66.6 COG1195@1|root,COG1195@2|Bacteria,1MX8N@1224|Proteobacteria,1RN5P@1236|Gammaproteobacteria,1YETD@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP recF GO:0000731,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0018130,GO:0019438,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - ko:K03629 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - SMC_N k141_29558_1 1279017.AQYJ01000029_gene3795 2.56e-96 300.0 COG3227@1|root,COG3227@2|Bacteria,1P416@1224|Proteobacteria,1RR7I@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Zinc metalloprotease (Elastase) nprV GO:0005575,GO:0005576,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0009405,GO:0019538,GO:0043170,GO:0044238,GO:0044419,GO:0051704,GO:0071704,GO:1901564 3.4.24.25,3.4.24.26 ko:K01399,ko:K08604 ko01503,ko02024,ko05110,ko05111,map01503,map02024,map05110,map05111 - - - ko00000,ko00001,ko01000,ko01002 - - - FTP,PPC,P_proprotein,PepSY,Peptidase_M4,Peptidase_M4_C k141_10544_1 96561.Dole_0983 6.5e-37 134.0 COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,42S1J@68525|delta/epsilon subdivisions,2WP2S@28221|Deltaproteobacteria,2MJG9@213118|Desulfobacterales 28221|Deltaproteobacteria I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family - - 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase k141_35626_1 218284.CCDN010000007_gene3953 6.3e-76 238.0 COG1502@1|root,COG1502@2|Bacteria,1USPT@1239|Firmicutes,4HCJD@91061|Bacilli,1ZC77@1386|Bacillus 91061|Bacilli I Belongs to the phospholipase D family. Cardiolipin synthase subfamily clsB GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0032048,GO:0032049,GO:0032502,GO:0043934,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 - ko:K06131 ko00564,ko01100,map00564,map01100 - R07390 RC00017 ko00000,ko00001,ko01000 - - - PLDc_2 k141_35626_2 218284.CCDN010000007_gene3952 9.11e-12 63.9 COG4294@1|root,COG4294@2|Bacteria,1TTCB@1239|Firmicutes,4H9PY@91061|Bacilli,1ZCJ7@1386|Bacillus 91061|Bacilli L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion uvsE - - ko:K13281 - - - - ko00000,ko01000 - - - UvdE k141_16469_1 1294265.JCM21738_1722 4.07e-108 315.0 COG0561@1|root,COG0561@2|Bacteria,1TR16@1239|Firmicutes,4HCZ6@91061|Bacilli,1ZCPY@1386|Bacillus 91061|Bacilli S hydrolases of the HAD superfamily ycsE - 3.1.3.104 ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R07280 RC00017 ko00000,ko00001,ko00002,ko01000 - - - Hydrolase_3 k141_31609_1 218284.CCDN010000001_gene1606 1.09e-56 181.0 COG0546@1|root,COG0546@2|Bacteria,1UI4N@1239|Firmicutes,4ISD8@91061|Bacilli,1ZS6H@1386|Bacillus 91061|Bacilli S HAD-hyrolase-like - - - ko:K07025 - - - - ko00000 - - - HAD_2 k141_31609_2 1196031.ALEG01000046_gene4561 1.36e-90 273.0 COG0500@1|root,COG0500@2|Bacteria,1UMPP@1239|Firmicutes,4ITY7@91061|Bacilli,1ZRID@1386|Bacillus 91061|Bacilli Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_11 k141_7955_1 1300005.R9RFD1_9CAUD 9.99e-13 82.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales 28883|Caudovirales S N-acetylmuramoyl-L-alanine amidase activity - - - - - - - - - - - - - k141_7955_8 140110.NechaP64589 6.16e-05 51.2 28PIZ@1|root,2QW74@2759|Eukaryota,38H8N@33154|Opisthokonta,3NYUT@4751|Fungi,3QMFV@4890|Ascomycota,212EN@147550|Sordariomycetes,3TGDN@5125|Hypocreales,1FR0N@110618|Nectriaceae 4751|Fungi E 2OG-Fe(II) oxygenase superfamily - - - - - - - - - - - - 2OG-FeII_Oxy_3 k141_7955_17 590998.Celf_0159 5.56e-05 47.8 COG3628@1|root,COG3628@2|Bacteria,2IFJ6@201174|Actinobacteria 201174|Actinobacteria S GPW gp25 family protein - - - ko:K06903 - - - - ko00000 - - - GPW_gp25 k141_7955_18 1283076.M1HLR4_9CAUD 1.08e-82 277.0 4QF7I@10239|Viruses,4QYCA@35237|dsDNA viruses no RNA stage,4QT9A@28883|Caudovirales,4QKJH@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k141_7955_20 1564096.A0A0A0YRA9_9CAUD 1.5e-216 691.0 4QEE7@10239|Viruses,4QPT7@28883|Caudovirales,4QI2X@10662|Myoviridae 10662|Myoviridae S Pfam:DUF4815 - - - - - - - - - - - - - k141_7955_22 1283076.M1I7U0_9CAUD 1.95e-53 181.0 4QCS3@10239|Viruses,4QY7T@35237|dsDNA viruses no RNA stage,4QU2E@28883|Caudovirales,4QKJF@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k141_7955_23 1357423.S5MPJ2_9CAUD 5.94e-41 145.0 4QDJF@10239|Viruses,4QVQ0@35237|dsDNA viruses no RNA stage,4QR89@28883|Caudovirales,4QICF@10662|Myoviridae 10662|Myoviridae S Virus neck protein - GO:0005575,GO:0019012 - - - - - - - - - - - k141_25021_2 218284.CCDN010000002_gene2087 1.29e-49 161.0 COG2151@1|root,COG2151@2|Bacteria,1V3QG@1239|Firmicutes,4HHST@91061|Bacilli,1ZBJH@1386|Bacillus 91061|Bacilli S Iron-sulfur cluster assembly protein paaD - - ko:K02612 ko00360,ko01120,map00360,map01120 - R09838 RC02690 ko00000,ko00001 - - - FeS_assembly_P k141_19093_1 1453501.JELR01000002_gene1381 5.65e-111 340.0 COG4774@1|root,COG4774@2|Bacteria,1NMCN@1224|Proteobacteria,1T3TQ@1236|Gammaproteobacteria,46DC7@72275|Alteromonadaceae 1236|Gammaproteobacteria P TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_8430_1 218284.CCDN010000001_gene700 1.15e-183 524.0 COG0768@1|root,COG0768@2|Bacteria,1TQKI@1239|Firmicutes,4HC5S@91061|Bacilli,1ZBDB@1386|Bacillus 91061|Bacilli M Penicillin-binding Protein pbpI - - ko:K21468 - - - - ko00000,ko01011 - - - PBP_dimer,Transpeptidase k141_22682_1 1279017.AQYJ01000028_gene2375 3.95e-213 599.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPWS@1236|Gammaproteobacteria,464W9@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0488 ATPase components of ABC transporters with duplicated ATPase domains yjjK GO:0003674,GO:0003824,GO:0005488,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:2000112,GO:2000113 3.6.3.25 ko:K06020 - - - - ko00000,ko01000 - - - ABC_tran,ABC_tran_Xtn k141_22682_2 1279017.AQYJ01000028_gene2376 5.5e-200 561.0 COG1024@1|root,COG1024@2|Bacteria,1MU0B@1224|Proteobacteria,1RN07@1236|Gammaproteobacteria,464P0@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1024 Enoyl-CoA hydratase carnithine racemase - - - - - - - - - - - - ECH_2 k141_22682_3 1453501.JELR01000002_gene561 6.3e-163 462.0 COG2084@1|root,COG2084@2|Bacteria,1RA7F@1224|Proteobacteria,1RMMY@1236|Gammaproteobacteria,464MY@72275|Alteromonadaceae 1236|Gammaproteobacteria I Belongs to the 3-hydroxyisobutyrate dehydrogenase family mmsB - 1.1.1.31 ko:K00020 ko00280,ko01100,map00280,map01100 - R05066 RC00099 ko00000,ko00001,ko01000 - - - NAD_binding_11,NAD_binding_2 k141_22682_4 1279017.AQYJ01000028_gene2379 2.39e-225 633.0 COG0635@1|root,COG0635@2|Bacteria,1MV1I@1224|Proteobacteria,1RN1Y@1236|Gammaproteobacteria,46465@72275|Alteromonadaceae 1236|Gammaproteobacteria H Belongs to the anaerobic coproporphyrinogen-III oxidase family hemN - 1.3.98.3 ko:K02495 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R06895 RC00884 ko00000,ko00001,ko00002,ko01000 - - - HemN_C,Radical_SAM k141_22682_5 1279017.AQYJ01000028_gene2380 8.42e-127 367.0 COG0664@1|root,COG0664@2|Bacteria,1MVGE@1224|Proteobacteria,1RPTB@1236|Gammaproteobacteria,466GX@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases fnr - - ko:K01420 - - - - ko00000,ko03000 - - - HTH_Crp_2,cNMP_binding k141_22682_7 1279017.AQYJ01000028_gene2386 2.66e-63 201.0 COG3945@1|root,COG3945@2|Bacteria,1NE2M@1224|Proteobacteria,1SD78@1236|Gammaproteobacteria,4695P@72275|Alteromonadaceae 1236|Gammaproteobacteria S Hemerythrin HHE cation binding domain - - - - - - - - - - - - Hemerythrin k141_22682_9 1279017.AQYJ01000028_gene2378 5.5e-91 274.0 COG3047@1|root,COG3047@2|Bacteria,1NUZJ@1224|Proteobacteria,1RRRC@1236|Gammaproteobacteria,467CK@72275|Alteromonadaceae 1236|Gammaproteobacteria M Outer membrane protein W ompW - - ko:K07275 - - - - ko00000 - - - OmpW k141_22682_11 1279017.AQYJ01000028_gene2389 6.07e-291 796.0 COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,1RMHQ@1236|Gammaproteobacteria,4641N@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism glyA GO:0001505,GO:0003674,GO:0003824,GO:0004372,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006546,GO:0006563,GO:0006565,GO:0006730,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009069,GO:0009070,GO:0009071,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016741,GO:0016742,GO:0017144,GO:0019264,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042133,GO:0042135,GO:0042136,GO:0042737,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0065007,GO:0065008,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 - - iG2583_1286.G2583_3081 SHMT k141_22682_12 1042377.AFPJ01000032_gene2724 2.13e-237 666.0 COG1231@1|root,COG1231@2|Bacteria,1PN11@1224|Proteobacteria,1SXFQ@1236|Gammaproteobacteria,46CCE@72275|Alteromonadaceae 1236|Gammaproteobacteria E Flavin containing amine oxidoreductase - - 1.4.3.4 ko:K00274 ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034 M00135 R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354 RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713 ko00000,ko00001,ko00002,ko01000 - - - Amino_oxidase k141_6037_1 1294265.JCM21738_4385 3.7e-122 353.0 COG1028@1|root,COG1028@2|Bacteria,1U36W@1239|Firmicutes,4HAA8@91061|Bacilli,1ZBU4@1386|Bacillus 91061|Bacilli IQ Enoyl-(Acyl carrier protein) reductase fabG9 - - - - - - - - - - - adh_short_C2 k141_7194_1 1279017.AQYJ01000028_gene2391 1.51e-217 605.0 COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,1RN2M@1236|Gammaproteobacteria,464V2@72275|Alteromonadaceae 1236|Gammaproteobacteria H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate ribD GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006725,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008703,GO:0008835,GO:0009058,GO:0009110,GO:0009231,GO:0009451,GO:0009987,GO:0016070,GO:0016491,GO:0016614,GO:0016616,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0034641,GO:0036094,GO:0042364,GO:0042726,GO:0042727,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.1.1.193,3.5.4.26 ko:K01498,ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 M00125 R03458,R03459 RC00204,RC00933 ko00000,ko00001,ko00002,ko01000 - - iB21_1397.B21_00366,iECBD_1354.ECBD_3247,iECB_1328.ECB_00362,iECD_1391.ECD_00362,iECED1_1282.ECED1_0437,iECNA114_1301.ECNA114_0391,iECSF_1327.ECSF_0374,iEcolC_1368.EcolC_3219,iJN746.PP_0514,iLF82_1304.LF82_1880,iNRG857_1313.NRG857_01945,iYL1228.KPN_00366,ic_1306.c0524 RibD_C,dCMP_cyt_deam_1 k141_7194_3 1042377.AFPJ01000024_gene724 8.01e-189 533.0 COG0687@1|root,COG0687@2|Bacteria,1MUYW@1224|Proteobacteria,1RM7W@1236|Gammaproteobacteria,4654B@72275|Alteromonadaceae 1236|Gammaproteobacteria E Required for the activity of the bacterial periplasmic transport system of putrescine potF - - ko:K11073 ko02010,map02010 M00300 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.2 - - SBP_bac_6,SBP_bac_8 k141_28627_1 218284.CCDN010000004_gene3024 4.29e-141 419.0 COG2183@1|root,COG2183@2|Bacteria,1TPFE@1239|Firmicutes,4HAGY@91061|Bacilli,1ZC3T@1386|Bacillus 91061|Bacilli K COG2183 Transcriptional accessory protein tex - - ko:K06959 - - - - ko00000 - - - HHH_3,S1,Tex_N,Tex_YqgF k141_33365_1 218284.CCDN010000008_gene4151 3.86e-78 239.0 COG0803@1|root,COG0803@2|Bacteria,1TPG7@1239|Firmicutes,4H9UN@91061|Bacilli,1ZC2Z@1386|Bacillus 91061|Bacilli P Belongs to the bacterial solute-binding protein 9 family adcA - - ko:K09815,ko:K09818 ko02010,map02010 M00242,M00243 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 - - ZnuA k141_33365_2 218284.CCDN010000008_gene4150 1.3e-26 107.0 COG1271@1|root,COG1271@2|Bacteria,1TRH4@1239|Firmicutes,4HA19@91061|Bacilli,1ZBAG@1386|Bacillus 91061|Bacilli C oxidase, subunit ythA - 1.10.3.14 ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - Cyt_bd_oxida_I k141_31006_2 218284.CCDN010000005_gene3254 9.86e-60 196.0 COG0446@1|root,COG0446@2|Bacteria,1TPWW@1239|Firmicutes,4HA11@91061|Bacilli,1ZATE@1386|Bacillus 91061|Bacilli P Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain cdr - 1.8.1.14 ko:K08255 - - - - ko00000,ko01000 - - - Pyr_redox_2,Pyr_redox_dim,Rhodanese,TusA k141_8431_1 218284.CCDN010000002_gene2560 7.79e-80 240.0 COG0454@1|root,COG0456@2|Bacteria,1V6D6@1239|Firmicutes,4HIQX@91061|Bacilli,1ZGF7@1386|Bacillus 91061|Bacilli K Acetyltransferase (GNAT) domain yxbD GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0044424,GO:0044464 3.2.2.20 ko:K01246 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Acetyltransf_1 k141_21503_1 1294265.JCM21738_5086 1.13e-123 369.0 COG2766@1|root,COG2766@2|Bacteria,1TRTW@1239|Firmicutes,4HA8A@91061|Bacilli,1ZBM9@1386|Bacillus 91061|Bacilli T Ser protein kinase prkA - - ko:K07180 - - - - ko00000 - - - AAA_PrkA,PrkA k141_22683_1 1196031.ALEG01000012_gene792 1e-101 306.0 COG0439@1|root,COG0439@2|Bacteria,1TP16@1239|Firmicutes,4HARK@91061|Bacilli,1ZC56@1386|Bacillus 91061|Bacilli I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism accC - 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 k141_10757_1 218284.CCDN010000001_gene659 3.12e-136 400.0 COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,4HAB7@91061|Bacilli,1ZDHC@1386|Bacillus 91061|Bacilli S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid spoVB - - ko:K06409 - - - - ko00000,ko02000 2.A.66.2.14 - - Polysacc_synt,Polysacc_synt_C k141_10757_2 218284.CCDN010000001_gene660 1.99e-59 185.0 2E6NG@1|root,3318Y@2|Bacteria,1VHES@1239|Firmicutes,4HP4D@91061|Bacilli,1ZJ02@1386|Bacillus 91061|Bacilli S Post-transcriptional regulator yrzD - - - - - - - - - - - Post_transc_reg k141_102_1 985255.APHJ01000023_gene2683 5.47e-05 45.8 COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,1HY4Z@117743|Flavobacteriia,2P7DW@244698|Gillisia 976|Bacteroidetes S ATPase family associated with various cellular activities (AAA) - - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 k141_102_2 1279017.AQYJ01000027_gene1717 7.31e-78 240.0 COG1721@1|root,COG1721@2|Bacteria,1MWPG@1224|Proteobacteria,1S4TD@1236|Gammaproteobacteria,46B1X@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function DUF58 - - - - - - - - - - - - DUF58 k141_11956_1 218284.CCDN010000003_gene2995 6.36e-73 224.0 2BYDV@1|root,32RAH@2|Bacteria,1V91M@1239|Firmicutes,4HIIQ@91061|Bacilli,1ZH7H@1386|Bacillus 91061|Bacilli S spore cortex biosynthesis protein yabQ GO:0005575,GO:0005623,GO:0042601,GO:0042763,GO:0044464 - - - - - - - - - - Spore_YabQ k141_19112_2 1196323.ALKF01000177_gene1079 9.01e-23 99.8 2DBJR@1|root,2Z9N7@2|Bacteria,1TRSN@1239|Firmicutes,4HCDI@91061|Bacilli,26RRB@186822|Paenibacillaceae 91061|Bacilli S PFAM spore germination B3 GerAC family protein - - - ko:K06297 - - - - ko00000 - - - Spore_GerAC k141_22698_1 265729.GS18_0216955 1.82e-41 141.0 COG2318@1|root,COG2318@2|Bacteria,1V6UF@1239|Firmicutes,4HIPX@91061|Bacilli,1ZD6H@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF664) - - - - - - - - - - - - DUF664 k141_22698_2 1385511.N783_15845 9.22e-20 88.6 COG0639@1|root,COG0639@2|Bacteria,1UYWX@1239|Firmicutes,4HEJF@91061|Bacilli 91061|Bacilli T Calcineurin-like phosphoesterase - - 3.1.3.16 ko:K01090 - - - - ko00000,ko01000 - - - Metallophos k141_28659_1 1042377.AFPJ01000025_gene616 9.37e-78 236.0 COG1225@1|root,COG1225@2|Bacteria,1RD2X@1224|Proteobacteria,1S3TJ@1236|Gammaproteobacteria,4673G@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG0526 Thiol-disulfide isomerase and thioredoxins - - - - - - - - - - - - AhpC-TSA k141_28659_2 1121921.KB898706_gene2414 3.69e-223 639.0 COG4232@1|root,COG4233@1|root,COG4232@2|Bacteria,COG4233@2|Bacteria,1MU8W@1224|Proteobacteria,1RPF7@1236|Gammaproteobacteria,2PN90@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria CO Disulphide bond corrector protein DsbC - - 1.8.1.8 ko:K04084 - - - - ko00000,ko01000,ko03110 5.A.1.1 - - DsbC,DsbD,Thioredoxin_7 k141_16722_2 1453501.JELR01000006_gene37 4.14e-199 557.0 COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,1RMKW@1236|Gammaproteobacteria,464VM@72275|Alteromonadaceae 1236|Gammaproteobacteria J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) queA GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009314,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0050896,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 ko:K07568 - - - - ko00000,ko01000,ko03016 - - - Queuosine_synth k141_13212_1 1122134.KB893650_gene23 8.19e-73 225.0 COG1028@1|root,COG1028@2|Bacteria,1MWJI@1224|Proteobacteria,1S2WT@1236|Gammaproteobacteria,1XR57@135619|Oceanospirillales 135619|Oceanospirillales IQ KR domain - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 k141_13212_2 523791.Kkor_0387 7.27e-98 300.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,1XHE8@135619|Oceanospirillales 135619|Oceanospirillales C belongs to the aldehyde dehydrogenase family - - 1.2.1.32,1.2.1.60,1.2.1.8,1.2.1.85 ko:K00130,ko:K00151,ko:K10217 ko00260,ko00350,ko00362,ko00380,ko00622,ko01100,ko01120,ko01220,map00260,map00350,map00362,map00380,map00622,map01100,map01120,map01220 M00038,M00533,M00555,M00569 R02565,R02566,R02762,R03889,R04418,R05353 RC00080,RC00218,RC00254 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_17972_1 218284.CCDN010000001_gene1227 3.46e-72 216.0 2FBM7@1|root,343SB@2|Bacteria,1VAAQ@1239|Firmicutes,4HYUG@91061|Bacilli,1ZIA3@1386|Bacillus 91061|Bacilli S YodL-like yodL - - - - - - - - - - - YodL k141_21534_1 1453501.JELR01000002_gene907 1.48e-25 104.0 COG3523@1|root,COG3523@2|Bacteria,1MV3D@1224|Proteobacteria,1RPQ2@1236|Gammaproteobacteria,464BZ@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria icmF - - ko:K11891 ko02025,ko03070,map02025,map03070 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - IcmF-related,IcmF_C,ImcF-related_N k141_21534_2 1453501.JELR01000002_gene908 2.84e-108 317.0 COG3455@1|root,COG3455@2|Bacteria,1MU13@1224|Proteobacteria,1RPVN@1236|Gammaproteobacteria,46CJF@72275|Alteromonadaceae 1236|Gammaproteobacteria S Type VI secretion system protein DotU - - - ko:K11892 ko03070,map03070 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - DotU k141_15581_1 218284.CCDN010000002_gene2855 2.81e-191 572.0 COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1TQ0B@1239|Firmicutes,4HA4G@91061|Bacilli,1ZBFF@1386|Bacillus 91061|Bacilli E glutamate synthase gltA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14,1.4.7.1 ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 - R00021,R00093,R00114,R00248,R10086 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - GATase_2,GXGXG,Glu_syn_central,Glu_synthase k141_25039_1 218284.CCDN010000002_gene2038 8.29e-117 360.0 COG0457@1|root,COG0457@2|Bacteria,1UATF@1239|Firmicutes,4HE1D@91061|Bacilli,1ZBPM@1386|Bacillus 91061|Bacilli S ATPase. Has a role at an early stage in the morphogenesis of the spore coat - - - - - - - - - - - - Dynamin_N,TPR_8 k141_27409_1 218284.CCDN010000001_gene940 7.62e-41 144.0 COG0404@1|root,COG0404@2|Bacteria,1TRKX@1239|Firmicutes,4H9MX@91061|Bacilli,1ZAS5@1386|Bacillus 91061|Bacilli E The glycine cleavage system catalyzes the degradation of glycine gcvT - 2.1.2.10 ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 M00532 R01221,R02300,R04125 RC00022,RC00069,RC00183,RC02834 ko00000,ko00001,ko00002,ko01000 - - - GCV_T,GCV_T_C k141_2492_1 314345.SPV1_00345 3.66e-261 756.0 COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria 1224|Proteobacteria P ATPase, P-type transporting, HAD superfamily, subfamily IC - - 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3 k141_2492_2 330214.NIDE3851 2.36e-283 790.0 COG0365@1|root,COG0365@2|Bacteria,3J0BJ@40117|Nitrospirae 2|Bacteria I Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA acsA - 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACAS_N,AMP-binding,AMP-binding_C k141_2492_3 1240349.ANGC01000066_gene90 1.93e-144 418.0 COG1071@1|root,COG1071@2|Bacteria,2IBRC@201174|Actinobacteria,4FUP9@85025|Nocardiaceae 201174|Actinobacteria C The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) pdhA - 1.2.4.1 ko:K00161,ko:K21416 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh k141_2492_4 930171.Asphe3_00700 7.36e-168 476.0 COG0022@1|root,COG0022@2|Bacteria,2GKFE@201174|Actinobacteria 201174|Actinobacteria C Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit - - 1.2.4.1 ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C k141_2492_5 279714.FuraDRAFT_0733 1.57e-121 363.0 COG0508@1|root,COG0508@2|Bacteria,1MUGY@1224|Proteobacteria,2VN6N@28216|Betaproteobacteria,2KTC7@206351|Neisseriales 206351|Neisseriales C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex - - 2.3.1.12 ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding k141_2492_6 1121033.AUCF01000041_gene455 3.22e-13 66.2 COG0236@1|root,COG0236@2|Bacteria,1QA4W@1224|Proteobacteria,2UKMK@28211|Alphaproteobacteria,2JUVB@204441|Rhodospirillales 204441|Rhodospirillales IQ Phosphopantetheine attachment site - - - - - - - - - - - - PP-binding k141_2492_7 857087.Metme_3277 6.4e-137 403.0 COG0695@1|root,COG0695@2|Bacteria,1QVSK@1224|Proteobacteria,1T3G3@1236|Gammaproteobacteria,1XDZF@135618|Methylococcales 135618|Methylococcales O PFAM glutaredoxin - - - - - - - - - - - - Glutaredoxin k141_2492_8 56780.SYN_01162 2.74e-51 169.0 COG0428@1|root,COG0428@2|Bacteria,1R40E@1224|Proteobacteria,43B49@68525|delta/epsilon subdivisions,2X6I2@28221|Deltaproteobacteria 28221|Deltaproteobacteria P ZIP Zinc transporter - - - ko:K16267 - - - - ko00000,ko02000 2.A.5.4.11 - - Zip k141_2492_9 1415778.JQMM01000001_gene2182 4.67e-60 199.0 COG0224@1|root,COG0224@2|Bacteria,1RIE5@1224|Proteobacteria,1S3ZW@1236|Gammaproteobacteria 1236|Gammaproteobacteria C ATP synthase gamma subunit - - - ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt k141_2492_10 1415778.JQMM01000001_gene2181 3.5e-238 669.0 COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,1RP4V@1236|Gammaproteobacteria,1J5DU@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit atpA1 - 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N k141_2492_11 522306.CAP2UW1_2681 4.33e-34 130.0 COG0711@1|root,COG0712@1|root,COG0711@2|Bacteria,COG0712@2|Bacteria,1R6C0@1224|Proteobacteria,2VNRP@28216|Betaproteobacteria 28216|Betaproteobacteria C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) - - - ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_B,DUF2934,OSCP k141_2492_13 1415778.JQMM01000001_gene2178 3.27e-110 323.0 COG0356@1|root,COG0356@2|Bacteria,1RBEV@1224|Proteobacteria,1T170@1236|Gammaproteobacteria 1236|Gammaproteobacteria C it plays a direct role in the translocation of protons across the membrane - - - ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 - - ATP-synt_A k141_2492_14 472759.Nhal_2240 4.14e-30 109.0 2E70X@1|root,331JP@2|Bacteria,1N81S@1224|Proteobacteria,1SCI0@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - ko:K02116 - - - - ko00000,ko00194 3.A.2.1 - - ATPase_gene1 k141_2492_15 338966.Ppro_0850 6.05e-27 104.0 COG0355@1|root,COG0355@2|Bacteria,1N1NE@1224|Proteobacteria 1224|Proteobacteria C atp synthase atpC_2 - - ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_DE_N k141_2492_16 697282.Mettu_0385 1.62e-170 488.0 COG0055@1|root,COG0055@2|Bacteria,1N6UZ@1224|Proteobacteria,1RNQW@1236|Gammaproteobacteria,1XDWQ@135618|Methylococcales 135618|Methylococcales C PFAM ATPase, F1 V1 A1 complex, alpha beta subunit, nucleotide-binding domain - - 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_N k141_20276_2 298386.PBPRB0044 1.02e-52 170.0 COG0454@1|root,COG0456@2|Bacteria,1N506@1224|Proteobacteria,1S97J@1236|Gammaproteobacteria,1XY4G@135623|Vibrionales 135623|Vibrionales K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1 k141_20276_3 1042377.AFPJ01000053_gene1516 7.76e-128 375.0 COG2067@1|root,COG2067@2|Bacteria,1MV7W@1224|Proteobacteria,1RPTU@1236|Gammaproteobacteria,469RP@72275|Alteromonadaceae 1236|Gammaproteobacteria I Outer membrane protein transport protein (OMPP1/FadL/TodX) - - - ko:K06076 - - - - ko00000,ko02000 1.B.9 - - Toluene_X k141_36917_1 1118055.CAGU01000006_gene966 6.5e-56 182.0 COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia,22G2A@1570339|Peptoniphilaceae 186801|Clostridia J Belongs to the universal ribosomal protein uS2 family rpsB - - ko:K02967 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S2 k141_36917_2 518766.Rmar_0006 2.74e-44 148.0 COG0103@1|root,COG0103@2|Bacteria,4NNN1@976|Bacteroidetes,1FJFJ@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes J Belongs to the universal ribosomal protein uS9 family rpsI GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02996 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S9 k141_36917_3 28042.GU90_05155 1.14e-64 201.0 COG0102@1|root,COG0102@2|Bacteria,2IFG1@201174|Actinobacteria,4E2WQ@85010|Pseudonocardiales 201174|Actinobacteria J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly rplM GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02871 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L13 k141_36917_4 1089548.KI783301_gene2771 4.45e-06 48.9 COG0182@1|root,COG0182@2|Bacteria,1TPDK@1239|Firmicutes,4H9WM@91061|Bacilli,3WF5H@539002|Bacillales incertae sedis 91061|Bacilli E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) mtnA - 5.3.1.23 ko:K08963 ko00270,ko01100,map00270,map01100 M00034 R04420 RC01151 ko00000,ko00001,ko00002,ko01000 - - - IF-2B k141_33380_1 1007103.AFHW01000146_gene5072 3.27e-58 196.0 COG1866@1|root,COG1866@2|Bacteria,1TPQV@1239|Firmicutes,4HAKG@91061|Bacilli,26S9A@186822|Paenibacillaceae 91061|Bacilli C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA pckA GO:0000166,GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0017076,GO:0019318,GO:0019319,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576 4.1.1.49 ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 M00003,M00170 R00341 RC00002,RC02741 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS09060,iYO844.BSU30560 PEPCK_ATP k141_33380_2 477974.Daud_2209 2e-41 149.0 COG0104@1|root,COG0104@2|Bacteria,1TQ4C@1239|Firmicutes,247RN@186801|Clostridia,260YE@186807|Peptococcaceae 186801|Clostridia F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP purA - 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 - - - Adenylsucc_synt k141_13214_1 868595.Desca_2372 3e-20 93.6 COG2206@1|root,COG2206@2|Bacteria,1TQIM@1239|Firmicutes,248S5@186801|Clostridia,260W0@186807|Peptococcaceae 186801|Clostridia T PFAM Metal-dependent phosphohydrolase, HD - - - - - - - - - - - - HD,HD_5 k141_3679_1 1116375.VEJY3_13815 1.67e-65 206.0 COG2165@1|root,COG2165@2|Bacteria,1QUGH@1224|Proteobacteria,1T1Y8@1236|Gammaproteobacteria,1XXTW@135623|Vibrionales 135623|Vibrionales NU COG2165 Type II secretory pathway, pseudopilin PulG mshD - - ko:K10927 ko05111,map05111 - - - ko00000,ko00001,ko02044 - - - N_methyl k141_3679_2 1116375.VEJY3_13820 1.27e-61 194.0 COG2165@1|root,COG2165@2|Bacteria,1N9YF@1224|Proteobacteria,1SDMA@1236|Gammaproteobacteria,1XYDJ@135623|Vibrionales 135623|Vibrionales NU Prokaryotic N-terminal methylation motif mshC - - ko:K10926 ko05111,map05111 - - - ko00000,ko00001,ko02044 - - - N_methyl k141_3679_3 1051646.VITU9109_08171 1.77e-43 148.0 COG2165@1|root,COG2165@2|Bacteria,1N7HN@1224|Proteobacteria,1SDMJ@1236|Gammaproteobacteria,1XXUV@135623|Vibrionales 135623|Vibrionales NU Prokaryotic N-terminal methylation motif - - - ko:K10924 ko05111,map05111 - - - ko00000,ko00001,ko02044 - - - N_methyl k141_22699_1 997296.PB1_13449 1.23e-65 207.0 COG0207@1|root,COG0207@2|Bacteria,1TSIR@1239|Firmicutes,4H9QS@91061|Bacilli,1ZAUT@1386|Bacillus 91061|Bacilli F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis thyA GO:0003674,GO:0003824,GO:0004799,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0032259,GO:0034641,GO:0034654,GO:0042083,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046385,GO:0046483,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 - - - Thymidylat_synt k141_22699_3 545695.TREAZ_0540 3.71e-12 63.9 COG0756@1|root,COG0756@2|Bacteria,2J7JH@203691|Spirochaetes 203691|Spirochaetes F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA dut - 3.6.1.23 ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00053 R02100,R11896 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 - - - dUTPase k141_131_2 1279017.AQYJ01000022_gene2702 4.43e-81 248.0 COG0589@1|root,COG0589@2|Bacteria,1PAFP@1224|Proteobacteria,1RSCS@1236|Gammaproteobacteria,465CE@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - - - - - - - - - - Usp k141_14385_1 1294265.JCM21738_3210 4.71e-225 623.0 COG0592@1|root,COG0592@2|Bacteria,1TQ7J@1239|Firmicutes,4H9TF@91061|Bacilli,1ZAVV@1386|Bacillus 91061|Bacilli L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria dnaN - 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_beta,DNA_pol3_beta_3 k141_23849_1 1243664.CAVL020000010_gene4532 1.3e-68 224.0 COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,4HADT@91061|Bacilli,1ZC5H@1386|Bacillus 91061|Bacilli KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains - - - - - - - - - - - - HTH_8,PAS,PAS_9,Sigma54_activat k141_8460_2 1279017.AQYJ01000028_gene2133 4.79e-72 241.0 COG0834@1|root,COG4623@1|root,COG0834@2|Bacteria,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,1RM8W@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella - GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - ko:K18691 - - - - ko00000,ko01000,ko01011 - - - SBP_bac_3,SLT k141_21535_1 94122.Shewana3_2915 4.7e-151 442.0 COG4974@1|root,COG4974@2|Bacteria,1QVZC@1224|Proteobacteria,1T2P4@1236|Gammaproteobacteria,2QET5@267890|Shewanellaceae 1236|Gammaproteobacteria L Phage integrase family - - - - - - - - - - - - Phage_integrase k141_20277_2 765910.MARPU_03015 8.26e-52 166.0 COG1733@1|root,COG1733@2|Bacteria,1MZ6G@1224|Proteobacteria,1S941@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator - - - - - - - - - - - - HxlR k141_2493_1 1121935.AQXX01000072_gene3 1.18e-18 93.6 COG1572@1|root,COG2304@1|root,COG3209@1|root,COG1572@2|Bacteria,COG2304@2|Bacteria,COG3209@2|Bacteria,1QU09@1224|Proteobacteria,1T39R@1236|Gammaproteobacteria 1236|Gammaproteobacteria N Protein involved in outer membrane biogenesis - - - - - - - - - - - - He_PIG,RHS_repeat k141_33381_1 218284.CCDN010000012_gene4433 3.1e-114 334.0 28JUG@1|root,2Z9JI@2|Bacteria,1UYYT@1239|Firmicutes,4HC3E@91061|Bacilli,1ZBYK@1386|Bacillus 91061|Bacilli S YaaC-like Protein yaaC - - - - - - - - - - - YaaC k141_36918_1 1042377.AFPJ01000029_gene532 1.55e-160 455.0 COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,1RN7F@1236|Gammaproteobacteria,4643F@72275|Alteromonadaceae 1236|Gammaproteobacteria J Responsible for synthesis of pseudouridine from uracil rluD GO:0000027,GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022607,GO:0022613,GO:0022618,GO:0031118,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 ko:K06180 - - - - ko00000,ko01000,ko03009 - - iE2348C_1286.E2348C_2868,iECED1_1282.ECED1_3035,iECSF_1327.ECSF_2432 PseudoU_synth_2,S4 k141_19115_1 1279017.AQYJ01000026_gene376 1.39e-20 95.9 COG0834@1|root,COG4623@1|root,COG0834@2|Bacteria,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,1RM8W@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella - GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - ko:K18691 - - - - ko00000,ko01000,ko01011 - - - SBP_bac_3,SLT k141_22700_2 441769.ABFU01000024_gene1028 4.89e-40 135.0 COG4476@1|root,COG4476@2|Bacteria,1VEK8@1239|Firmicutes,4HNKR@91061|Bacilli,1ZHT9@1386|Bacillus 91061|Bacilli S Belongs to the UPF0223 family yktA - - - - - - - - - - - UPF0223 k141_7218_1 1116375.VEJY3_11640 7.07e-226 627.0 COG1344@1|root,COG1344@2|Bacteria,1MV1N@1224|Proteobacteria,1RN0Y@1236|Gammaproteobacteria,1XTVF@135623|Vibrionales 135623|Vibrionales N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella flaE GO:0005575,GO:0005576,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 - - - ko00000,ko00001,ko02035 - - - Flagellin_C,Flagellin_IN,Flagellin_N k141_7218_2 1116375.VEJY3_11645 1.86e-212 587.0 COG2837@1|root,COG2837@2|Bacteria,1MWDD@1224|Proteobacteria,1RMZJ@1236|Gammaproteobacteria,1XU5E@135623|Vibrionales 135623|Vibrionales P iron-dependent peroxidase - - - ko:K07223 - - - - ko00000 - - - Dyp_perox k141_7218_3 1116375.VEJY3_11650 3.65e-107 309.0 2C10D@1|root,33BS1@2|Bacteria,1NK6Q@1224|Proteobacteria,1SH7K@1236|Gammaproteobacteria,1XXNW@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF2919) - - - - - - - - - - - - DUF2919 k141_7218_4 1116375.VEJY3_11655 7.91e-38 130.0 2E37U@1|root,32Y7H@2|Bacteria,1N8JQ@1224|Proteobacteria,1SCAH@1236|Gammaproteobacteria,1XYDU@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF2956) VC2147 - - - - - - - - - - - DUF2956 k141_8462_1 218284.CCDN010000001_gene945 2.11e-124 358.0 COG0095@1|root,COG0095@2|Bacteria,1TQ5U@1239|Firmicutes,4HABG@91061|Bacilli,1ZBG2@1386|Bacillus 91061|Bacilli H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation lipM GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 6.3.1.20 ko:K03800 ko00785,ko01100,map00785,map01100 - R07770,R07771,R11143 RC00043,RC00070,RC00090,RC00992,RC02896 ko00000,ko00001,ko01000 - - - BPL_LplA_LipB k141_26284_1 218284.CCDN010000001_gene1383 8.31e-110 322.0 COG0345@1|root,COG0345@2|Bacteria,1TP1E@1239|Firmicutes,4H9RV@91061|Bacilli,1ZCWZ@1386|Bacillus 91061|Bacilli E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline proC - 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU18480 F420_oxidored,P5CR_dimer k141_29804_1 1123228.AUIH01000003_gene809 8.87e-42 140.0 COG1017@1|root,COG1017@2|Bacteria,1RI9P@1224|Proteobacteria,1S7H7@1236|Gammaproteobacteria,1XMN2@135619|Oceanospirillales 135619|Oceanospirillales C nitric oxide dioxygenase activity - - - - - - - - - - - - - k141_29804_2 1279017.AQYJ01000028_gene2101 0.0 1348.0 COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,1RN05@1236|Gammaproteobacteria,46ABX@72275|Alteromonadaceae 1236|Gammaproteobacteria S Insulinase (Peptidase family M16) pqqL - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C k141_4870_1 223926.28809552 1.54e-223 622.0 COG0477@1|root,COG2814@2|Bacteria,1MW59@1224|Proteobacteria,1RNUU@1236|Gammaproteobacteria,1XUVX@135623|Vibrionales 135623|Vibrionales EGP of the major facilitator superfamily VPA1184 - - - - - - - - - - - MFS_1,Sugar_tr k141_4870_2 674977.VMC_37950 2.64e-90 273.0 COG0722@1|root,COG0722@2|Bacteria,1MU5Q@1224|Proteobacteria,1RMAA@1236|Gammaproteobacteria,1XSHG@135623|Vibrionales 135623|Vibrionales E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) aroG - 2.5.1.54 ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 - - - DAHP_synth_1 k141_9597_2 1116375.VEJY3_20061 5.5e-111 322.0 COG3124@1|root,COG3124@2|Bacteria,1MZ59@1224|Proteobacteria,1S9IZ@1236|Gammaproteobacteria,1XX07@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria acpH - 3.1.4.14 ko:K08682 ko00770,map00770 - R01623 - ko00000,ko00001,ko01000 - - - ACP_PD k141_25262_1 218284.CCDN010000008_gene4198 3.19e-148 438.0 COG1523@1|root,COG1523@2|Bacteria,1TP3M@1239|Firmicutes,4HBP5@91061|Bacilli,1ZC85@1386|Bacillus 91061|Bacilli G Belongs to the glycosyl hydrolase 13 family amyX - 3.2.1.41 ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 - R02111 - ko00000,ko00001,ko01000 - CBM48,GH13 - Alpha-amylase,CBM_48 k141_20425_1 1294265.JCM21738_3417 2.09e-194 556.0 COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,4HADT@91061|Bacilli,1ZAZA@1386|Bacillus 91061|Bacilli KT Transcriptional regulator bkdR - - - - - - - - - - - DapB_N,HTH_8,PAS,Sigma54_activat k141_14522_1 218284.CCDN010000001_gene1195 1.54e-102 300.0 2C2Z4@1|root,2ZEX2@2|Bacteria,1V1N0@1239|Firmicutes,4ISUP@91061|Bacilli,1ZS6C@1386|Bacillus 91061|Bacilli S YpjP-like protein - - - - - - - - - - - - YpjP k141_33551_1 45351.EDO25981 2.84e-96 298.0 COG0841@1|root,2RHH3@2759|Eukaryota,39SPV@33154|Opisthokonta,3BNMU@33208|Metazoa 33208|Metazoa V AcrB/AcrD/AcrF family - - - ko:K07798 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.6.1.4,8.A.1 - - ACR_tran k141_18185_1 1294265.JCM21738_3445 1.19e-93 275.0 COG1971@1|root,COG1971@2|Bacteria,1V4QK@1239|Firmicutes,4HH7C@91061|Bacilli,1ZFK0@1386|Bacillus 91061|Bacilli P Probably functions as a manganese efflux pump mntP - - - - - - - - - - - Mntp k141_12257_1 1196031.ALEG01000039_gene1164 5.13e-66 228.0 COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,4HA3G@91061|Bacilli,1ZAVY@1386|Bacillus 91061|Bacilli T Diguanylate cyclase - - - - - - - - - - - - EAL,FIST,FIST_C,GAF_2,GGDEF,PAS,PAS_4,PAS_9,dCache_1 k141_2690_2 218284.CCDN010000001_gene1088 2.53e-149 424.0 COG3409@1|root,COG3773@1|root,COG3409@2|Bacteria,COG3773@2|Bacteria,1TRFW@1239|Firmicutes,4HA2V@91061|Bacilli,1ZB40@1386|Bacillus 91061|Bacilli M Spore cortex-lytic enzyme sleB GO:0005575,GO:0005623,GO:0042763,GO:0044464 3.5.1.28 ko:K01449 - - R04112 RC00064,RC00141 ko00000,ko01000 - - - Hydrolase_2,PG_binding_1 k141_24032_1 42565.FP66_08800 1.67e-114 337.0 COG0126@1|root,COG0126@2|Bacteria,1MUNU@1224|Proteobacteria,1RMUQ@1236|Gammaproteobacteria,1XH3J@135619|Oceanospirillales 135619|Oceanospirillales F Belongs to the phosphoglycerate kinase family pgk - 2.7.2.3 ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01512 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGK k141_3908_1 218284.CCDN010000002_gene2140 1.18e-133 389.0 COG3314@1|root,COG3314@2|Bacteria,1TR35@1239|Firmicutes,4HAB6@91061|Bacilli,1ZARZ@1386|Bacillus 91061|Bacilli S protein conserved in bacteria - - - - - - - - - - - - Gate k141_15760_1 218284.CCDN010000004_gene3154 1.14e-182 517.0 COG4399@1|root,COG4399@2|Bacteria,1TQDH@1239|Firmicutes,4HA30@91061|Bacilli,1ZB1W@1386|Bacillus 91061|Bacilli S Belongs to the UPF0754 family yheB - - - - - - - - - - - DUF445 k141_33552_1 406124.ACPC01000045_gene4001 2.64e-120 348.0 COG2022@1|root,COG2022@2|Bacteria,1TQZ1@1239|Firmicutes,4HBSI@91061|Bacilli,1ZB9S@1386|Bacillus 91061|Bacilli H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S thiG GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 ko:K03149 ko00730,ko01100,map00730,map01100 - R10247 RC03096,RC03097,RC03461 ko00000,ko00001,ko01000 - - - ThiG k141_32293_2 1348635.BBJY01000014_gene936 1.61e-74 227.0 COG1280@1|root,COG1280@2|Bacteria,1RASZ@1224|Proteobacteria,1S56X@1236|Gammaproteobacteria,1XX3Q@135623|Vibrionales 135623|Vibrionales E threonine efflux protein - - - - - - - - - - - - LysE k141_35901_2 1462526.BN990_00059 1.31e-49 175.0 COG1396@1|root,COG1396@2|Bacteria,1TR8B@1239|Firmicutes,4HETZ@91061|Bacilli 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_3 k141_9771_1 338966.Ppro_3484 4.41e-41 147.0 COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,42MAI@68525|delta/epsilon subdivisions,2WJ8M@28221|Deltaproteobacteria,43T78@69541|Desulfuromonadales 28221|Deltaproteobacteria J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) gltX - 6.1.1.17 ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 - - - tRNA-synt_1c k141_9771_2 338963.Pcar_1651 2.15e-05 45.8 COG1355@1|root,COG1355@2|Bacteria,1MXK5@1224|Proteobacteria,42R55@68525|delta/epsilon subdivisions,2WN4E@28221|Deltaproteobacteria,43THN@69541|Desulfuromonadales 28221|Deltaproteobacteria S Belongs to the MEMO1 family - - - ko:K06990 - - - - ko00000,ko04812 - - - Memo k141_26596_1 1192034.CAP_7007 5.1e-13 70.1 COG4798@1|root,COG4798@2|Bacteria,1NNHX@1224|Proteobacteria,437RC@68525|delta/epsilon subdivisions,2X304@28221|Deltaproteobacteria,2YTVQ@29|Myxococcales 28221|Deltaproteobacteria S methyltransferase - - - - - - - - - - - - PCMT k141_5023_2 1279017.AQYJ01000028_gene2394 3e-97 285.0 COG0054@1|root,COG0054@2|Bacteria,1RD9J@1224|Proteobacteria,1S3WD@1236|Gammaproteobacteria,466GG@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin ribH GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R04457 RC00960 ko00000,ko00001,ko00002,ko01000 - - iSFV_1184.SFV_0380 DMRL_synthase k141_18186_1 1042377.AFPJ01000024_gene715 6.39e-05 43.9 COG1267@1|root,COG1267@2|Bacteria,1MZJA@1224|Proteobacteria,1S68A@1236|Gammaproteobacteria,467H1@72275|Alteromonadaceae 1236|Gammaproteobacteria I Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) pgpA GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008962,GO:0009058,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0030258,GO:0031224,GO:0031226,GO:0032026,GO:0042221,GO:0042577,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0046839,GO:0050896,GO:0071704,GO:0071944,GO:0090407,GO:1901576 3.1.3.27 ko:K01095 ko00564,ko01100,map00564,map01100 - R02029 RC00017 ko00000,ko00001,ko01000 - - iECSP_1301.ECSP_0485,iECUMN_1333.ECUMN_0456,iECs_1301.ECs0471,iG2583_1286.G2583_0529,iPC815.YPO3179,iZ_1308.Z0520 PgpA k141_18186_2 1042377.AFPJ01000024_gene714 5.05e-67 209.0 COG3577@1|root,COG3577@2|Bacteria,1N2PE@1224|Proteobacteria,1S66F@1236|Gammaproteobacteria,467QR@72275|Alteromonadaceae 1236|Gammaproteobacteria S gag-polyprotein putative aspartyl protease - - - ko:K06985 ko04112,map04112 - - - ko00000,ko00001 - - - gag-asp_proteas k141_3909_1 2002.JOEQ01000048_gene7447 6.53e-102 303.0 COG1117@1|root,COG1117@2|Bacteria,2GJQ3@201174|Actinobacteria,4EM3I@85012|Streptosporangiales 201174|Actinobacteria P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system pstB - 3.6.3.27 ko:K02036 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 - - ABC_tran k141_3909_2 926550.CLDAP_00820 4.39e-16 76.6 COG0581@1|root,COG0581@2|Bacteria,2G6BI@200795|Chloroflexi 200795|Chloroflexi P TIGRFAM phosphate ABC transporter, inner membrane subunit PstA - - - ko:K02038 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 k141_12259_1 1294265.JCM21738_2960 8.56e-10 56.6 COG0715@1|root,COG0715@2|Bacteria,1TQN5@1239|Firmicutes,4HAB9@91061|Bacilli,1ZC0Z@1386|Bacillus 91061|Bacilli P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components ytlA GO:0003674,GO:0005215 - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1,NMT1_2 k141_12259_2 1294265.JCM21738_2959 2.7e-103 303.0 COG1506@1|root,COG1506@2|Bacteria,1U5SB@1239|Firmicutes,4HB1A@91061|Bacilli,1ZC9W@1386|Bacillus 91061|Bacilli E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases ytmA - - - - - - - - - - - Peptidase_S9 k141_2691_1 272624.lpg2192 7.7e-50 166.0 COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,1SC4Z@1236|Gammaproteobacteria,1JEEB@118969|Legionellales 118969|Legionellales O Belongs to the small heat shock protein (HSP20) family - - - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 k141_28872_1 218284.CCDN010000001_gene1273 7.92e-81 257.0 COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,1TSAC@1239|Firmicutes,4HAJG@91061|Bacilli,1ZB2G@1386|Bacillus 91061|Bacilli L ATP-dependent DNA ligase ligD - 6.5.1.1 ko:K01971 ko03450,map03450 - R00381 RC00005 ko00000,ko00001,ko01000,ko03400 - - - DNA_ligase_A_M k141_28872_2 218284.CCDN010000001_gene1272 1.49e-76 237.0 COG0253@1|root,COG0253@2|Bacteria,1TPMN@1239|Firmicutes,4HBH4@91061|Bacilli,1ZD98@1386|Bacillus 91061|Bacilli E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan dapF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 - - - DAP_epimerase k141_19292_1 1279017.AQYJ01000027_gene1861 2.1e-262 724.0 COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,1RPV9@1236|Gammaproteobacteria,46535@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0581 ABC-type phosphate transport system, permease component pstA - - ko:K02038 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1,DUF3333 k141_16972_2 1453501.JELR01000002_gene1001 9.66e-66 201.0 COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,1S67I@1236|Gammaproteobacteria,467D0@72275|Alteromonadaceae 1236|Gammaproteobacteria K Belongs to the P(II) protein family glnK - - ko:K04752 - - - - ko00000 - - - P-II k141_12260_1 1279017.AQYJ01000029_gene3957 3.32e-78 261.0 COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,1RMPT@1236|Gammaproteobacteria,464DD@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG3209 Rhs family protein - - - - - - - - - - - - RHS_repeat,SpvB,TcdB_toxin_midN,VCBS k141_29933_2 1279017.AQYJ01000028_gene2334 8.45e-72 235.0 COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,1RNRX@1236|Gammaproteobacteria,464V1@72275|Alteromonadaceae 1236|Gammaproteobacteria P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) ppk GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006082,GO:0006091,GO:0006139,GO:0006163,GO:0006165,GO:0006464,GO:0006468,GO:0006725,GO:0006753,GO:0006757,GO:0006793,GO:0006796,GO:0006797,GO:0006799,GO:0006807,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009117,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009179,GO:0009185,GO:0009199,GO:0009205,GO:0009259,GO:0009279,GO:0009358,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016778,GO:0017144,GO:0019538,GO:0019637,GO:0019693,GO:0019867,GO:0030312,GO:0030313,GO:0031241,GO:0031975,GO:0032991,GO:0034641,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0043751,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044425,GO:0044462,GO:0044464,GO:0046031,GO:0046034,GO:0046483,GO:0046777,GO:0046939,GO:0055086,GO:0061695,GO:0071704,GO:0071944,GO:0072521,GO:0098552,GO:1901135,GO:1901360,GO:1901564,GO:1901576,GO:1902494,GO:1990234 2.7.4.1 ko:K00937 ko00190,ko03018,map00190,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - iSbBS512_1146.SbBS512_E2875 PP_kinase,PP_kinase_C,PP_kinase_N k141_395_1 338966.Ppro_2736 6.9e-05 45.1 COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,42PGW@68525|delta/epsilon subdivisions,2WMMZ@28221|Deltaproteobacteria,43TCD@69541|Desulfuromonadales 28221|Deltaproteobacteria C PFAM Alcohol dehydrogenase zinc-binding domain protein - - - - - - - - - - - - ADH_N,ADH_zinc_N k141_395_2 260799.BAS3212 1.07e-134 388.0 COG0491@1|root,COG0491@2|Bacteria,1TSM4@1239|Firmicutes,4HBZ2@91061|Bacilli,1ZDRZ@1386|Bacillus 91061|Bacilli S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B k141_13424_1 547163.BN979_06693 3.21e-11 63.2 COG3588@1|root,COG3588@2|Bacteria,2GN1A@201174|Actinobacteria,233KA@1762|Mycobacteriaceae 201174|Actinobacteria G Aldolase fda - 4.1.2.13 ko:K01623 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000,ko03036,ko04131,ko04147 - - - Glycolytic k141_29945_1 796606.BMMGA3_11670 1.87e-120 352.0 COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,4HBAU@91061|Bacilli,1ZBV8@1386|Bacillus 91061|Bacilli G Glucokinase glcK GO:0003674,GO:0003824,GO:0004340,GO:0004396,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044464,GO:0046835,GO:0051156,GO:0071704,GO:1901135 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS07790 ROK k141_29945_2 1294265.JCM21738_5470 3.72e-36 122.0 COG4483@1|root,COG4483@2|Bacteria,1VK83@1239|Firmicutes,4HRG2@91061|Bacilli,1ZISV@1386|Bacillus 91061|Bacilli S protein conserved in bacteria yqgQ - - - - - - - - - - - DUF910 k141_14534_1 1121090.KB894685_gene4097 2.68e-08 53.5 COG0425@1|root,COG0607@1|root,COG0425@2|Bacteria,COG0607@2|Bacteria,1V1GU@1239|Firmicutes,4HFR8@91061|Bacilli,1ZAVN@1386|Bacillus 91061|Bacilli OP Belongs to the sulfur carrier protein TusA family yrkF - - - - - - - - - - - Rhodanese,TusA k141_14534_2 1294265.JCM21738_1260 6.01e-83 254.0 COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,1TPE2@1239|Firmicutes,4H9WH@91061|Bacilli,1ZCD8@1386|Bacillus 91061|Bacilli P Rhodanese Homology Domain yrkH - - - - - - - - - - - Lactamase_B,Rhodanese k141_9781_1 1196028.ALEF01000037_gene832 8e-165 466.0 COG0697@1|root,COG0697@2|Bacteria,1TRKD@1239|Firmicutes,4HA3N@91061|Bacilli,4C5DJ@84406|Virgibacillus 91061|Bacilli EG EamA-like transporter family - - - - - - - - - - - - EamA k141_9781_2 218284.CCDN010000002_gene2817 8.86e-68 217.0 2CDJQ@1|root,2Z7JX@2|Bacteria,1TR73@1239|Firmicutes,4HAT1@91061|Bacilli,1ZRA6@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_33573_1 1121374.KB891588_gene3289 2.65e-83 265.0 COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,1RPSJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria T signal-transduction protein containing cAMP-binding and CBS domains - - - ko:K07182 - - - - ko00000 - - - CBS,DUF294,DUF294_C,cNMP_binding k141_25280_1 218284.CCDN010000001_gene796 1.73e-61 213.0 COG0297@1|root,COG0297@2|Bacteria,1UHYC@1239|Firmicutes,4ISUZ@91061|Bacilli,1ZD41@1386|Bacillus 91061|Bacilli G Starch synthase catalytic domain - - - - - - - - - - - - Glyco_hydro_57,Glyco_transf_4,Glycos_transf_1 k141_3935_1 1034347.CAHJ01000059_gene683 9.2e-125 369.0 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli,1ZAXK@1386|Bacillus 91061|Bacilli C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively iolA - 1.2.1.18,1.2.1.27 ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 M00013 R00705,R00706,R00922,R00935 RC00004,RC02723,RC02817 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_9782_1 218284.CCDN010000001_gene1873 6.17e-129 381.0 COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,4HAAP@91061|Bacilli,1ZB4E@1386|Bacillus 91061|Bacilli S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay rnjB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 - ko:K12574 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - Lactamase_B,RMMBL k141_7439_2 218284.CCDN010000004_gene3032 1.88e-168 474.0 COG1366@1|root,COG1366@2|Bacteria,1UGQT@1239|Firmicutes,4HCRH@91061|Bacilli,1ZBRY@1386|Bacillus 91061|Bacilli T Positive regulator of sigma-B rsbR - - ko:K17763 - - - - ko00000,ko03021 - - - Rsbr_N,STAS k141_7439_4 218284.CCDN010000004_gene3030 3.63e-89 261.0 COG2172@1|root,COG2172@2|Bacteria,1V6Y4@1239|Firmicutes,4HIQU@91061|Bacilli,1ZG7T@1386|Bacillus 91061|Bacilli T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase) rsbT - 2.7.11.1 ko:K17752 - - - - ko00000,ko01000,ko01001,ko03021 - - - HATPase_c,HATPase_c_2 k141_31237_1 223926.28808615 2.19e-233 658.0 COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,1RSP9@1236|Gammaproteobacteria,1XXZ7@135623|Vibrionales 135623|Vibrionales O Subtilase family - - - - - - - - - - - - Peptidase_S8 k141_31237_2 357804.Ping_0274 6.69e-22 89.0 COG4519@1|root,COG4519@2|Bacteria,1N38K@1224|Proteobacteria,1SENE@1236|Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - HTH_43 k141_31237_3 945543.VIBR0546_18606 1.89e-146 415.0 2BYAF@1|root,2ZWH8@2|Bacteria,1RBZ8@1224|Proteobacteria,1S2EB@1236|Gammaproteobacteria,1XTF5@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF3581) - - - - - - - - - - - - DUF3581 k141_31237_4 1116375.VEJY3_04060 1.43e-161 455.0 COG1028@1|root,COG1028@2|Bacteria,1MUD2@1224|Proteobacteria,1RN5N@1236|Gammaproteobacteria,1XW3H@135623|Vibrionales 135623|Vibrionales IQ KR domain vibA - 1.3.1.28 ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 - R01505 RC00534 ko00000,ko00001,ko01000 - - - adh_short_C2 k141_31237_5 1116375.VEJY3_04065 7.81e-217 603.0 2AMVA@1|root,31CS1@2|Bacteria,1NAQ1@1224|Proteobacteria,1SEY4@1236|Gammaproteobacteria,1XU8D@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_6366_2 5888.CAK71825 1.95e-18 84.0 COG0111@1|root,KOG0068@2759|Eukaryota,3ZBC7@5878|Ciliophora 5878|Ciliophora E D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - - - - - - - - - - 2-Hacid_dh,2-Hacid_dh_C k141_22933_2 1453501.JELR01000001_gene2934 7.9e-26 104.0 COG4805@1|root,COG4805@2|Bacteria,1MZDR@1224|Proteobacteria,1RZK8@1236|Gammaproteobacteria,465YN@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein conserved in bacteria - - - - - - - - - - - - - k141_12282_1 1353528.DT23_07265 1.08e-53 177.0 COG0745@1|root,COG0745@2|Bacteria,1N0YI@1224|Proteobacteria,2VEXA@28211|Alphaproteobacteria,2XPJI@285107|Thioclava 28211|Alphaproteobacteria K Transcriptional regulatory protein, C terminal - - - ko:K07666 ko02020,ko02024,map02020,map02024 M00453 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C k141_35916_1 1294265.JCM21738_3238 1.13e-41 140.0 COG0629@1|root,COG0629@2|Bacteria,1V3WT@1239|Firmicutes,4HH8I@91061|Bacilli,1ZFIJ@1386|Bacillus 91061|Bacilli L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k141_35916_2 1294265.JCM21738_3239 1.13e-47 152.0 COG0238@1|root,COG0238@2|Bacteria,1V9XS@1239|Firmicutes,4HKCC@91061|Bacilli,1ZHUE@1386|Bacillus 91061|Bacilli J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit rpsR GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02963 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S18 k141_37081_1 1042377.AFPJ01000007_gene1864 5.89e-51 168.0 COG0665@1|root,COG0665@2|Bacteria,1RH7N@1224|Proteobacteria,1S9ZE@1236|Gammaproteobacteria,467V9@72275|Alteromonadaceae 1236|Gammaproteobacteria E tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity - - - - - - - - - - - - - k141_37081_2 1453501.JELR01000001_gene2410 0.0 1389.0 COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,1RN05@1236|Gammaproteobacteria,464MR@72275|Alteromonadaceae 1236|Gammaproteobacteria S Insulinase (Peptidase family M16) pqqL - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C k141_26626_1 218284.CCDN010000005_gene3242 3e-147 427.0 COG1233@1|root,COG1233@2|Bacteria,1TRN1@1239|Firmicutes,4HA5W@91061|Bacilli,1ZDED@1386|Bacillus 91061|Bacilli Q Flavin containing amine oxidoreductase - - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 ko:K10027 ko00906,ko01100,ko01110,map00906,map01100,map01110 - R04787,R04798,R04800,R09691,R09692 RC01214,RC02088,RC02605 ko00000,ko00001,ko01000 - - - Amino_oxidase k141_29946_1 218284.CCDN010000007_gene3907 1.3e-126 370.0 COG3852@1|root,COG3852@2|Bacteria,1TRH0@1239|Firmicutes,4HD4A@91061|Bacilli,1ZARI@1386|Bacillus 91061|Bacilli T COG0642 Signal transduction histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,PAS,PAS_4,PAS_9 k141_13426_1 218284.CCDN010000001_gene1079 2.69e-40 137.0 2E8AX@1|root,309PA@2|Bacteria,1U5FH@1239|Firmicutes,4IF70@91061|Bacilli,1ZKD7@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_13426_2 218284.CCDN010000001_gene1080 8.6e-47 158.0 COG1408@1|root,COG1408@2|Bacteria,1V494@1239|Firmicutes,4HH1B@91061|Bacilli,1ZBFW@1386|Bacillus 91061|Bacilli S Calcineurin-like phosphoesterase superfamily domain ypbG - - ko:K07098 - - - - ko00000 - - - Metallophos,Metallophos_2 k141_9783_1 986075.CathTA2_1863 1.49e-37 140.0 COG0508@1|root,COG0508@2|Bacteria,1TR5N@1239|Firmicutes,4HA7A@91061|Bacilli 91061|Bacilli C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex pdhC - 2.3.1.12 ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding k141_32312_1 1279017.AQYJ01000029_gene3685 1.2e-172 490.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RW1Q@1236|Gammaproteobacteria,4663X@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1960 Acyl-CoA dehydrogenases atuD - - ko:K11731 ko00281,map00281 - R08089 RC01893 ko00000,ko00001,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_1440_1 1545915.JROG01000004_gene1997 1.31e-52 183.0 COG1228@1|root,COG1228@2|Bacteria,1MY4V@1224|Proteobacteria,2U3IV@28211|Alphaproteobacteria,2K1NC@204457|Sphingomonadales 204457|Sphingomonadales Q Amidohydrolase family - - - - - - - - - - - - Amidohydro_1 k141_396_2 1120953.AUBH01000002_gene1447 2.69e-188 548.0 COG3544@1|root,COG3544@2|Bacteria,1NTI3@1224|Proteobacteria,1T0HG@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF4142) - - - - - - - - - - - - DUF305 k141_5045_1 365048.Q0H279_9CAUD 2.89e-55 184.0 4QBHS@10239|Viruses,4QUVV@35237|dsDNA viruses no RNA stage,4QPT9@28883|Caudovirales 28883|Caudovirales S DNA metabolic process - - - - - - - - - - - - - k141_19306_1 1453501.JELR01000002_gene1076 1.54e-38 140.0 COG0534@1|root,COG0534@2|Bacteria,1MV6B@1224|Proteobacteria,1RPGF@1236|Gammaproteobacteria,46598@72275|Alteromonadaceae 1236|Gammaproteobacteria V COG0534 Na -driven multidrug efflux pump dinF - - ko:K03327 - - - - ko00000,ko02000 2.A.66.1 - - MatE k141_33576_1 218284.CCDN010000002_gene2812 7.21e-89 267.0 COG2207@1|root,COG3708@1|root,COG2207@2|Bacteria,COG3708@2|Bacteria,1TPI9@1239|Firmicutes,4HCJ8@91061|Bacilli,1ZAUV@1386|Bacillus 91061|Bacilli K AraC family transcriptional regulator - - - ko:K13653 - - - - ko00000,ko03000 - - - Cass2,GyrI-like,HTH_18 k141_12283_1 1042377.AFPJ01000037_gene2945 7.99e-145 415.0 COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,1RPRD@1236|Gammaproteobacteria,46576@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases ppsC - 1.6.5.5 ko:K00344 - - - - ko00000,ko01000 - - - ADH_N,ADH_zinc_N,ADH_zinc_N_2 k141_20444_1 218284.CCDN010000007_gene3947 4.02e-198 550.0 COG0421@1|root,COG0421@2|Bacteria,1TPG5@1239|Firmicutes,4H9WU@91061|Bacilli,1ZB0B@1386|Bacillus 91061|Bacilli E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine speE GO:0003674,GO:0003824,GO:0004766,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016740,GO:0016765,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 M00034,M00133 R01920,R02869,R08359 RC00021,RC00053 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU37500 Spermine_synt_N,Spermine_synth k141_20444_2 218284.CCDN010000007_gene3948 1.18e-120 350.0 COG0010@1|root,COG0010@2|Bacteria,1TP2A@1239|Firmicutes,4HA7S@91061|Bacilli,1ZB9A@1386|Bacillus 91061|Bacilli E Belongs to the arginase family speB - 3.5.3.11 ko:K01480 ko00330,ko01100,map00330,map01100 M00133 R01157 RC00024,RC00329 ko00000,ko00001,ko00002,ko01000 - - - Arginase k141_2711_1 42565.FP66_06735 2.37e-115 357.0 COG0553@1|root,COG0553@2|Bacteria,1MX6H@1224|Proteobacteria,1RNRZ@1236|Gammaproteobacteria,1XHNQ@135619|Oceanospirillales 135619|Oceanospirillales K Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair rapA - - ko:K03580 - - - - ko00000,ko01000,ko03021 - - - Helicase_C,RapA_C,ResIII,SNF2_N k141_25281_1 218284.CCDN010000002_gene2872 2.89e-150 427.0 COG3181@1|root,COG3181@2|Bacteria,1V0HH@1239|Firmicutes,4HBWA@91061|Bacilli,1ZB42@1386|Bacillus 91061|Bacilli S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC k141_21716_1 1116375.VEJY3_07060 0.0 906.0 COG1292@1|root,COG1292@2|Bacteria,1MV0K@1224|Proteobacteria,1RP3E@1236|Gammaproteobacteria,1XTJH@135623|Vibrionales 135623|Vibrionales M Belongs to the BCCT transporter (TC 2.A.15) family - - - ko:K03451 - - - - ko00000 2.A.15 - - BCCT k141_21716_2 1116375.VEJY3_07055 3.84e-107 310.0 COG3637@1|root,COG3637@2|Bacteria,1RHVI@1224|Proteobacteria,1S6UY@1236|Gammaproteobacteria,1XXFT@135623|Vibrionales 135623|Vibrionales M OmpA-like transmembrane domain - - - - - - - - - - - - OMP_b-brl k141_21716_3 674977.VMC_39830 2.57e-102 297.0 COG3637@1|root,COG3637@2|Bacteria,1RHVI@1224|Proteobacteria,1S6UY@1236|Gammaproteobacteria,1XVZ1@135623|Vibrionales 135623|Vibrionales M OmpA-like transmembrane domain - - - - - - - - - - - - OMP_b-brl k141_21716_4 674977.VMC_39840 1.85e-222 651.0 COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,1RMU1@1236|Gammaproteobacteria,1XSCH@135623|Vibrionales 135623|Vibrionales L COG1643 HrpA-like helicases hrpA - 3.6.4.13 ko:K03578 - - - - ko00000,ko01000 - - - DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind k141_29947_1 1042377.AFPJ01000030_gene469 2.52e-37 132.0 COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,1RMK4@1236|Gammaproteobacteria,464KN@72275|Alteromonadaceae 1236|Gammaproteobacteria M Involved in formation and maintenance of cell shape mreC GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007163,GO:0008150,GO:0008360,GO:0009987,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0043621,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944,GO:0071963 - ko:K03570 - - - - ko00000,ko03036 9.B.157.1 - - MreC k141_1441_1 42565.FP66_15475 5.63e-55 173.0 COG3492@1|root,COG3492@2|Bacteria,1MZ3I@1224|Proteobacteria,1S8SI@1236|Gammaproteobacteria,1XKGU@135619|Oceanospirillales 135619|Oceanospirillales S deoxycytidine triphosphate deaminase - - - ko:K09948 - - - - ko00000 - - - DUF1244 k141_1441_2 42565.FP66_15480 5.04e-36 125.0 COG0521@1|root,COG0521@2|Bacteria,1R9W2@1224|Proteobacteria,1S21E@1236|Gammaproteobacteria,1XJ5T@135619|Oceanospirillales 135619|Oceanospirillales H May be involved in the biosynthesis of molybdopterin moaB - 2.7.7.75 ko:K03638 ko00790,ko01100,map00790,map01100 - R09726 RC00002 ko00000,ko00001,ko01000 - - - MoCF_biosynth k141_32313_2 796606.BMMGA3_12665 4.89e-71 226.0 COG1388@1|root,COG1388@2|Bacteria,1U052@1239|Firmicutes,4HF2C@91061|Bacilli,1ZB2H@1386|Bacillus 91061|Bacilli M stage VI sporulation protein D spoVID GO:0003674,GO:0005488,GO:0005515,GO:0019899,GO:0051117 - ko:K06417 - - - - ko00000 - - - LysM k141_397_1 218284.CCDN010000003_gene2999 1.01e-45 163.0 COG2208@1|root,COG2208@2|Bacteria,1TQ92@1239|Firmicutes,4HB0X@91061|Bacilli,1ZAYZ@1386|Bacillus 91061|Bacilli KT stage II sporulation protein E spoIIE GO:0005575,GO:0005623,GO:0042601,GO:0042763,GO:0044464 3.1.3.16 ko:K06382 - - - - ko00000,ko01000 - - - SpoIIE k141_12284_1 218284.CCDN010000001_gene512 4.51e-98 292.0 COG0825@1|root,COG0825@2|Bacteria,1UHNS@1239|Firmicutes,4HA4C@91061|Bacilli,1ZC5V@1386|Bacillus 91061|Bacilli I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA accA - 2.1.3.15,6.4.1.2 ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - ACCA k141_10982_1 1116472.MGMO_45c00700 5.69e-32 118.0 COG3748@1|root,COG3748@2|Bacteria,1RFIZ@1224|Proteobacteria,1S8F8@1236|Gammaproteobacteria,1XEI4@135618|Methylococcales 135618|Methylococcales S Urate oxidase N-terminal - - - - - - - - - - - - Urate_ox_N k141_10982_2 94122.Shewana3_2554 2.5e-12 65.5 COG2084@1|root,COG2084@2|Bacteria,1MUGU@1224|Proteobacteria,1RQ2D@1236|Gammaproteobacteria,2QATY@267890|Shewanellaceae 1236|Gammaproteobacteria I NADP oxidoreductase coenzyme F420-dependent garR - 1.1.1.31,1.1.1.60 ko:K00020,ko:K00042 ko00280,ko00630,ko01100,map00280,map00630,map01100 - R01745,R01747,R05066 RC00099 ko00000,ko00001,ko01000 - - - NAD_binding_11,NAD_binding_2 k141_18443_2 1294265.JCM21738_2577 1.74e-34 118.0 2C7Y5@1|root,2ZW4E@2|Bacteria,1W5UC@1239|Firmicutes,4HZZW@91061|Bacilli,1ZJ0V@1386|Bacillus 91061|Bacilli S ComZ comZ - - ko:K02254 - - - - ko00000,ko02044 - - - ComZ k141_26901_1 1196031.ALEG01000005_gene5722 9.6e-96 284.0 COG0664@1|root,COG0664@2|Bacteria,1V3XW@1239|Firmicutes,4HDG1@91061|Bacilli,1ZCQ7@1386|Bacillus 91061|Bacilli K COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - ko:K10914,ko:K21828 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 - - - ko00000,ko00001,ko03000 - - - HTH_Crp_2,cNMP_binding k141_35018_1 1280001.BAOA01000038_gene4398 1.44e-79 252.0 COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,1RNQD@1236|Gammaproteobacteria,1XSY2@135623|Vibrionales 135623|Vibrionales H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) dxs GO:0003674,GO:0003824,GO:0006629,GO:0006720,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008614,GO:0008615,GO:0008661,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016744,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0042816,GO:0042819,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.2.1.7 ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 M00096 R05636 RC00032 ko00000,ko00001,ko00002,ko01000 - - - DXP_synthase_N,Transket_pyr,Transketolase_C k141_35018_2 1219076.N646_2840 8.63e-132 379.0 COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,1RMKY@1236|Gammaproteobacteria,1XTUM@135623|Vibrionales 135623|Vibrionales H Belongs to the FPP GGPP synthase family ispA - 2.5.1.1,2.5.1.10 ko:K00795 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364 R01658,R02003 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 - - - polyprenyl_synt k141_5355_1 1347369.CCAD010000041_gene805 2.64e-85 254.0 COG0233@1|root,COG0233@2|Bacteria,1V1F2@1239|Firmicutes,4HFSH@91061|Bacilli,1ZAZF@1386|Bacillus 91061|Bacilli J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another frr GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - ko:K02838 - - - - ko00000,ko03012 - - - RRF k141_27714_1 218284.CCDN010000001_gene1794 5.94e-109 316.0 COG1974@1|root,COG1974@2|Bacteria,1TQ3H@1239|Firmicutes,4HBHA@91061|Bacilli,1ZBMU@1386|Bacillus 91061|Bacilli K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair lexA GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 ko:K01356 - M00729 - - ko00000,ko00002,ko01000,ko01002,ko03400 - - - LexA_DNA_bind,Peptidase_S24 k141_11294_1 1078085.HMPREF1210_00657 2.69e-71 243.0 COG1404@1|root,COG2755@1|root,COG1404@2|Bacteria,COG2755@2|Bacteria,1TPH1@1239|Firmicutes,4HBQH@91061|Bacilli 91061|Bacilli O Belongs to the peptidase S8 family prtS - 3.4.21.110,3.4.21.96 ko:K01361,ko:K08652 - - - - ko00000,ko01000,ko01002,ko03110 - - - FIVAR,Gram_pos_anchor,Inhibitor_I9,PA,Peptidase_S8,SLH,YSIRK_signal,fn3_5 k141_20696_1 42565.FP66_09430 6.27e-37 137.0 COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,1RN6K@1236|Gammaproteobacteria,1XHJR@135619|Oceanospirillales 135619|Oceanospirillales C Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) aceE - 1.2.4.1 ko:K00163 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - Transketolase_N k141_20696_2 42565.FP66_09430 7.48e-80 258.0 COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,1RN6K@1236|Gammaproteobacteria,1XHJR@135619|Oceanospirillales 135619|Oceanospirillales C Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) aceE - 1.2.4.1 ko:K00163 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - Transketolase_N k141_2851_2 665952.HMPREF1015_01965 2.32e-14 68.2 COG1950@1|root,COG1950@2|Bacteria,1VF4I@1239|Firmicutes,4HNXP@91061|Bacilli,1ZI79@1386|Bacillus 91061|Bacilli S Membrane yvlD - - ko:K08972 - - - - ko00000 - - - Phage_holin_4_2 k141_24262_1 1294265.JCM21738_3388 6.19e-100 316.0 COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,4HAFP@91061|Bacilli,1ZBJ3@1386|Bacillus 91061|Bacilli V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran k141_12594_1 218284.CCDN010000001_gene1854 1.72e-96 286.0 COG1692@1|root,COG1692@2|Bacteria,1TR9P@1239|Firmicutes,4HAV5@91061|Bacilli,1ZC3D@1386|Bacillus 91061|Bacilli S protein conserved in bacteria ymdB GO:0003674,GO:0003824,GO:0004112,GO:0004113,GO:0008081,GO:0016787,GO:0016788,GO:0042578 - ko:K02029,ko:K02030,ko:K09769 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - YmdB k141_8915_2 1117647.M5M_16880 1.97e-29 115.0 2A65Z@1|root,30UYE@2|Bacteria,1RDBP@1224|Proteobacteria,1S5Q6@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_25583_1 1348635.BBJY01000016_gene3974 2.84e-201 557.0 COG4977@1|root,COG4977@2|Bacteria,1MVS8@1224|Proteobacteria,1RQ3Y@1236|Gammaproteobacteria,1XW7A@135623|Vibrionales 135623|Vibrionales K AraC-like ligand binding domain - - - ko:K02099 - - - - ko00000,ko03000 - - - AraC_binding,HTH_18,HTH_AraC k141_25583_2 1116375.VEJY3_24171 3.87e-53 166.0 2CC0C@1|root,32ZJ1@2|Bacteria,1R3EF@1224|Proteobacteria,1T671@1236|Gammaproteobacteria,1Y3DF@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF3297) - - - - - - - - - - - - DUF3297 k141_5356_1 1308866.J416_07657 1.49e-25 100.0 COG0290@1|root,COG0290@2|Bacteria,1V1RC@1239|Firmicutes,4HFUS@91061|Bacilli,46ZVW@74385|Gracilibacillus 91061|Bacilli J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins infC GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - ko:K02520 - - - - ko00000,ko03012,ko03029 - - - IF3_C,IF3_N k141_5356_2 983545.Glaag_2549 2.01e-13 64.7 COG0291@1|root,COG0291@2|Bacteria,1N6V4@1224|Proteobacteria,1SCHI@1236|Gammaproteobacteria,468CG@72275|Alteromonadaceae 1236|Gammaproteobacteria J Belongs to the bacterial ribosomal protein bL35 family rpmI GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02916 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L35p k141_35019_1 1042377.AFPJ01000038_gene1100 7.64e-11 61.2 COG4774@1|root,COG4774@2|Bacteria,1NMCN@1224|Proteobacteria,1T3TQ@1236|Gammaproteobacteria,46DC7@72275|Alteromonadaceae 1236|Gammaproteobacteria P TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_20697_1 215803.DB30_0989 3.05e-14 77.4 COG1948@1|root,COG4880@2|Bacteria,1PQKR@1224|Proteobacteria,438JJ@68525|delta/epsilon subdivisions,2X3U8@28221|Deltaproteobacteria,2YX4D@29|Myxococcales 28221|Deltaproteobacteria L Beta propeller domain - - - - - - - - - - - - Beta_propel k141_4157_1 218284.CCDN010000001_gene730 2.51e-192 547.0 COG0481@1|root,COG0481@2|Bacteria,1TP0G@1239|Firmicutes,4HASA@91061|Bacilli,1ZC7J@1386|Bacillus 91061|Bacilli M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner lepA - - ko:K03596 ko05134,map05134 - - - ko00000,ko00001 - - - EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C k141_24263_2 1134474.O59_001605 9.21e-17 80.1 COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,1RN13@1236|Gammaproteobacteria,1FH2W@10|Cellvibrio 1236|Gammaproteobacteria F Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine mtaD - 3.5.4.28,3.5.4.31 ko:K12960 ko00270,ko01100,map00270,map01100 - R09660 RC00477 ko00000,ko00001,ko01000 - - - Amidohydro_1 k141_18446_1 501479.ACNW01000050_gene3559 2.88e-93 280.0 COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,2TR14@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA rsmI - 2.1.1.198 ko:K07056 - - - - ko00000,ko01000,ko03009 - - - TP_methylase k141_19572_1 1042377.AFPJ01000030_gene500 1.45e-72 233.0 COG0364@1|root,COG0364@2|Bacteria,1MUN0@1224|Proteobacteria,1RN76@1236|Gammaproteobacteria,464A8@72275|Alteromonadaceae 1236|Gammaproteobacteria G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone zwf - 1.1.1.363,1.1.1.49 ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 M00004,M00006,M00008 R00835,R02736,R10907 RC00001,RC00066 ko00000,ko00001,ko00002,ko01000,ko04147 - - - G6PD_C,G6PD_N k141_13760_1 1453501.JELR01000002_gene615 2.27e-50 166.0 COG2995@1|root,COG2995@2|Bacteria,1MWG1@1224|Proteobacteria,1RM9Z@1236|Gammaproteobacteria,467ES@72275|Alteromonadaceae 1236|Gammaproteobacteria S paraquat-inducible protein A yebS GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0071944 - ko:K03808 - - - - ko00000 - - - PqiA k141_13760_2 1042377.AFPJ01000024_gene766 8.37e-88 266.0 COG2995@1|root,COG2995@2|Bacteria,1N2QU@1224|Proteobacteria,1S9RM@1236|Gammaproteobacteria,46CS5@72275|Alteromonadaceae 1236|Gammaproteobacteria S Paraquat-inducible protein A pqiA2 - - ko:K03808 - - - - ko00000 - - - PqiA k141_26903_1 218284.CCDN010000002_gene2239 4.32e-153 441.0 COG1966@1|root,COG1966@2|Bacteria,1TQN8@1239|Firmicutes,4H9SU@91061|Bacilli,1ZC6K@1386|Bacillus 91061|Bacilli T Carbon starvation protein cstA - - - - - - - - - - - CstA,CstA_5TM k141_24264_1 218284.CCDN010000002_gene2826 3.88e-75 233.0 COG4927@1|root,COG4927@2|Bacteria,1TQGX@1239|Firmicutes,4HATV@91061|Bacilli,1ZC2P@1386|Bacillus 91061|Bacilli S Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase - - - - - - - - - - - - AAT k141_7594_1 666686.B1NLA3E_17690 1.12e-188 542.0 COG1138@1|root,COG1138@2|Bacteria,1UH6S@1239|Firmicutes,4HF5S@91061|Bacilli,1ZD3Q@1386|Bacillus 91061|Bacilli O Cytochrome C assembly protein - - - ko:K02198 - - - - ko00000,ko02000 9.B.14.1 - - CcmF_C,Cytochrom_C_asm k141_27716_1 42565.FP66_10505 3.96e-95 289.0 COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,1RMVW@1236|Gammaproteobacteria,1XI8P@135619|Oceanospirillales 135619|Oceanospirillales M Belongs to the UDP-glucose GDP-mannose dehydrogenase family - - 1.1.1.22 ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 M00014,M00129,M00361,M00362 R00286 RC00291 ko00000,ko00001,ko00002,ko01000 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N k141_27716_2 42565.FP66_10510 2.82e-06 48.5 COG1215@1|root,COG1215@2|Bacteria,1NQ1J@1224|Proteobacteria,1RYM8@1236|Gammaproteobacteria 1236|Gammaproteobacteria M COG1215 Glycosyltransferases, probably involved in cell wall biogenesis alg8 - 2.4.1.33 ko:K19290 ko00051,map00051 - R08692 RC00005 ko00000,ko00001,ko01000,ko01003,ko02000 4.D.1.1.7,4.D.1.1.9 GT2 - Glyco_tranf_2_3 k141_12596_1 218284.CCDN010000001_gene371 6.03e-91 271.0 28ITW@1|root,2Z8SQ@2|Bacteria,1TSYI@1239|Firmicutes,4HADC@91061|Bacilli,1ZDIW@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_1646_1 571166.KI421509_gene2926 1.15e-47 174.0 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2TS19@28211|Alphaproteobacteria 28211|Alphaproteobacteria F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdZ - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_lgC,Ribonuc_red_lgN k141_11297_1 42565.FP66_01965 6.98e-15 72.8 COG1868@1|root,COG1868@2|Bacteria,1MX01@1224|Proteobacteria,1RQ8M@1236|Gammaproteobacteria,1XHYT@135619|Oceanospirillales 135619|Oceanospirillales N FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation fliM - - ko:K02416 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02035 - - - FliM,FliMN_C k141_11297_2 42565.FP66_01960 2.68e-68 209.0 COG1580@1|root,COG1580@2|Bacteria,1NADA@1224|Proteobacteria,1T0S6@1236|Gammaproteobacteria,1XPTB@135619|Oceanospirillales 135619|Oceanospirillales N Controls the rotational direction of flagella during chemotaxis - - - - - - - - - - - - FliL k141_25586_1 247634.GPB2148_400 4.5e-103 325.0 COG1629@1|root,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria,1J5SG@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec k141_2852_1 698769.JFBD01000091_gene2175 7.41e-76 236.0 COG1957@1|root,COG1957@2|Bacteria,1TRWG@1239|Firmicutes,4HCMZ@91061|Bacilli,4C50E@84406|Virgibacillus 91061|Bacilli F Inosine-uridine preferring nucleoside hydrolase rihA_1 - 3.2.2.1 ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 - R01245,R01273,R01677,R01770,R02143 RC00033,RC00063,RC00122,RC00318,RC00485 ko00000,ko00001,ko01000 - - - IU_nuc_hydro k141_2852_2 218284.CCDN010000001_gene1572 4.44e-48 157.0 COG0789@1|root,COG0789@2|Bacteria,1VA1B@1239|Firmicutes,4HKRD@91061|Bacilli,1ZHXG@1386|Bacillus 91061|Bacilli K transcriptional - - - - - - - - - - - - MerR,MerR-DNA-bind,MerR_1 k141_14711_1 1294265.JCM21738_4000 1.1e-60 197.0 COG1323@1|root,COG1323@2|Bacteria,1TPP2@1239|Firmicutes,4HAZJ@91061|Bacilli,1ZC63@1386|Bacillus 91061|Bacilli S Belongs to the UPF0348 family ylbM - - - - - - - - - - - HIGH_NTase1 k141_663_2 1116375.VEJY3_23516 3.74e-141 423.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XSRH@135623|Vibrionales 135623|Vibrionales T signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - 3.1.4.52 ko:K20962 ko05111,map05111 - - - ko00000,ko00001,ko01000 - - - EAL,GGDEF,Response_reg k141_6511_1 13690.CP98_05300 6.05e-55 196.0 COG3497@1|root,COG3497@2|Bacteria,1MX89@1224|Proteobacteria,2TVB3@28211|Alphaproteobacteria,2K9MI@204457|Sphingomonadales 204457|Sphingomonadales S Phage tail sheath C-terminal domain - - - ko:K06907 - - - - ko00000 - - - Phage_sheath_1,Phage_sheath_1C k141_25587_1 218284.CCDN010000006_gene3628 3.22e-112 328.0 COG1481@1|root,COG1481@2|Bacteria,1TP2X@1239|Firmicutes,4HB4H@91061|Bacilli,1ZBKY@1386|Bacillus 91061|Bacilli K May be required for sporulation whiA GO:0008150,GO:0043937,GO:0050789,GO:0050793,GO:0065007 - ko:K09762 - - - - ko00000 - - - HTH_WhiA,LAGLIDADG_WhiA,WhiA_N k141_18448_1 218284.CCDN010000007_gene3917 6.99e-40 137.0 COG3108@1|root,COG3409@1|root,COG3108@2|Bacteria,COG3409@2|Bacteria,1V2G4@1239|Firmicutes,4HRIA@91061|Bacilli,1ZFEE@1386|Bacillus 91061|Bacilli M Peptidase M15 - - 3.4.17.14 ko:K08640 - - - - ko00000,ko01000,ko01002,ko01011 - - - PG_binding_1,Peptidase_M15_3 k141_18448_2 218284.CCDN010000007_gene3916 3.76e-79 239.0 COG0860@1|root,COG0860@2|Bacteria,1V3MD@1239|Firmicutes,4HHD1@91061|Bacilli,1ZBPF@1386|Bacillus 91061|Bacilli M n-acetylmuramoyl-L-alanine amidase cwlC - 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - Amidase_3,PG_binding_1,SPOR k141_29021_1 218284.CCDN010000005_gene3170 5.07e-130 376.0 COG0760@1|root,COG0760@2|Bacteria,1TX3R@1239|Firmicutes,4HC85@91061|Bacilli,1ZC6P@1386|Bacillus 91061|Bacilli M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins prsA - 5.2.1.8 ko:K01802,ko:K07533 - - - - ko00000,ko01000,ko03110 - - - Rotamase_3,Trigger_C k141_17121_1 292415.Tbd_1466 3.3e-75 242.0 COG2187@1|root,COG2187@2|Bacteria,1R98V@1224|Proteobacteria,2VM22@28216|Betaproteobacteria,1KSS9@119069|Hydrogenophilales 119069|Hydrogenophilales S AAA domain - - - - - - - - - - - - - k141_17121_4 1279017.AQYJ01000027_gene1742 4.19e-115 340.0 COG4531@1|root,COG4531@2|Bacteria,1QTTI@1224|Proteobacteria,1RMRJ@1236|Gammaproteobacteria,467GB@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG4531 ABC-type Zn2 transport system, periplasmic component surface adhesin znuA - - ko:K09815 ko02010,map02010 M00242 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15.3,3.A.1.15.5 - - ZnuA k141_17121_5 1279017.AQYJ01000027_gene1743 2.53e-113 332.0 COG1121@1|root,COG1121@2|Bacteria,1MUDW@1224|Proteobacteria,1RPJT@1236|Gammaproteobacteria,465N4@72275|Alteromonadaceae 1236|Gammaproteobacteria P Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system znuC GO:0000041,GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005385,GO:0005488,GO:0005524,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008144,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043492,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0072509,GO:0072511,GO:0097159,GO:0097367,GO:0098655,GO:0098660,GO:0098662,GO:1901265,GO:1901363 - ko:K09817 ko02010,map02010 M00242 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.15.3,3.A.1.15.5 - iSFV_1184.SFV_1859,iSF_1195.SF1867,iSFxv_1172.SFxv_2092,iS_1188.S1934 ABC_tran k141_24266_1 492774.JQMB01000007_gene4137 8.72e-49 164.0 29CEM@1|root,2ZZD2@2|Bacteria,1RKJK@1224|Proteobacteria,2TVUC@28211|Alphaproteobacteria,4BADG@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_24266_2 1453501.JELR01000001_gene2662 4.68e-226 635.0 COG0114@1|root,COG0114@2|Bacteria,1MUQI@1224|Proteobacteria,1RNUS@1236|Gammaproteobacteria,464A2@72275|Alteromonadaceae 1236|Gammaproteobacteria C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate fumC - 4.2.1.2 ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 M00009,M00011,M00173,M00376 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - - FumaraseC_C,Lyase_1 k141_24266_5 1453501.JELR01000001_gene2660 5.73e-219 608.0 COG2207@1|root,COG2207@2|Bacteria,1R4MG@1224|Proteobacteria,1RQ8P@1236|Gammaproteobacteria,466QB@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG2207 AraC-type DNA-binding domain-containing proteins - - - - - - - - - - - - Arabinose_bd,HTH_18 k141_24266_6 1453501.JELR01000001_gene2659 0.0 1097.0 COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,1RNV1@1236|Gammaproteobacteria,463Y9@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1960 Acyl-CoA dehydrogenases HA62_19490 - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N k141_24266_8 1453501.JELR01000001_gene2657 0.0 954.0 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1RMQ4@1236|Gammaproteobacteria,4654E@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II fadD - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding,AMP-binding_C k141_24266_9 1453501.JELR01000001_gene2656 2.35e-62 196.0 COG3431@1|root,COG3431@2|Bacteria,1RJWK@1224|Proteobacteria,1S2UP@1236|Gammaproteobacteria,467I3@72275|Alteromonadaceae 1236|Gammaproteobacteria S Phosphate-starvation-inducible E - - - - - - - - - - - - PsiE k141_24266_10 1453501.JELR01000001_gene2655 2.58e-313 865.0 COG2234@1|root,COG2234@2|Bacteria,1MV86@1224|Proteobacteria,1RNNQ@1236|Gammaproteobacteria,464MC@72275|Alteromonadaceae 1236|Gammaproteobacteria S Peptidase family M28 - - - - - - - - - - - - PA,Peptidase_M28 k141_24266_11 1279017.AQYJ01000029_gene3419 1.53e-248 684.0 COG2866@1|root,COG2866@2|Bacteria,1MUMN@1224|Proteobacteria,1RQB4@1236|Gammaproteobacteria,465EV@72275|Alteromonadaceae 1236|Gammaproteobacteria E Zn_pept - - - - - - - - - - - - Peptidase_M14 k141_24266_13 1042377.AFPJ01000036_gene1262 1.35e-95 283.0 COG2930@1|root,COG2930@2|Bacteria,1RCH3@1224|Proteobacteria,1S2SV@1236|Gammaproteobacteria,466VF@72275|Alteromonadaceae 1236|Gammaproteobacteria S Las17-binding protein actin regulator VPA0371 - - - - - - - - - - - Ysc84 k141_24266_14 1042377.AFPJ01000036_gene1263 2.54e-68 211.0 2C4GG@1|root,331DQ@2|Bacteria,1N7QC@1224|Proteobacteria,1SCI3@1236|Gammaproteobacteria,468SZ@72275|Alteromonadaceae 1236|Gammaproteobacteria S Polyribonucleotide nucleotidyltransferase - - - - - - - - - - - - - k141_12611_1 1042377.AFPJ01000034_gene2426 9.57e-23 97.1 COG1982@1|root,COG1982@2|Bacteria,1MWK4@1224|Proteobacteria,1RMVF@1236|Gammaproteobacteria,464W7@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG1982 Arginine lysine ornithine decarboxylases - - 4.1.1.19 ko:K01584,ko:K01585 ko00330,ko01100,map00330,map01100 M00133 R00566 RC00299 ko00000,ko00001,ko00002,ko01000 - - - OKR_DC_1,OKR_DC_1_C k141_12611_2 1279017.AQYJ01000024_gene950 3.44e-74 224.0 COG1051@1|root,COG1051@2|Bacteria,1QVYW@1224|Proteobacteria,1T2NC@1236|Gammaproteobacteria 1236|Gammaproteobacteria F NUDIX domain - - - - - - - - - - - - NUDIX k141_32494_2 218284.CCDN010000007_gene3815 6.44e-88 259.0 COG0359@1|root,COG0359@2|Bacteria,1V6QG@1239|Firmicutes,4HIKJ@91061|Bacilli,1ZGEE@1386|Bacillus 91061|Bacilli J binds to the 23S rRNA rplI GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02939 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L9_C,Ribosomal_L9_N k141_5370_1 1453501.JELR01000002_gene1334 9.75e-141 423.0 COG2755@1|root,COG2755@2|Bacteria,1MXTS@1224|Proteobacteria,1RTPH@1236|Gammaproteobacteria,46419@72275|Alteromonadaceae 1236|Gammaproteobacteria E Concanavalin A-like lectin/glucanases superfamily - - - - - - - - - - - - Laminin_G_3 k141_13776_1 1042377.AFPJ01000036_gene1168 1.36e-209 593.0 COG1680@1|root,COG1680@2|Bacteria,1MY4Y@1224|Proteobacteria,1RY1C@1236|Gammaproteobacteria,466BA@72275|Alteromonadaceae 1236|Gammaproteobacteria V Beta-lactamase - - - - - - - - - - - - Beta-lactamase k141_13776_2 305700.B447_04557 8.32e-74 232.0 COG4464@1|root,COG4464@2|Bacteria,1R5E2@1224|Proteobacteria,2VS99@28216|Betaproteobacteria,2KWZ0@206389|Rhodocyclales 206389|Rhodocyclales GM capsular polysaccharide biosynthesis protein - - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - - k141_13776_3 1042377.AFPJ01000052_gene1537 8.31e-204 600.0 COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,1MVI9@1224|Proteobacteria,1RNB0@1236|Gammaproteobacteria,46617@72275|Alteromonadaceae 1236|Gammaproteobacteria D protein involved in exopolysaccharide biosynthesis - - - ko:K16554,ko:K16692 ko05111,map05111 - - - ko00000,ko00001,ko01000,ko01001,ko02000 8.A.3.1 - - AAA_31,CbiA,GNVR,Wzz k141_13776_4 1298865.H978DRAFT_1008 2.16e-59 190.0 COG1596@1|root,COG1596@2|Bacteria,1MXYS@1224|Proteobacteria,1SC60@1236|Gammaproteobacteria,467H9@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG1596 Periplasmic protein involved in polysaccharide export gumB - - ko:K20988 ko05111,map05111 - - - ko00000,ko00001,ko02000 1.B.18 - - Poly_export,SLBB k141_25609_1 1279017.AQYJ01000020_gene1256 1.28e-89 268.0 COG1028@1|root,COG1028@2|Bacteria,1MUUV@1224|Proteobacteria,1RMJU@1236|Gammaproteobacteria,466CG@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) ycdF - 1.5.1.33 ko:K03793 - - - - ko00000,ko01000 - - - adh_short_C2 k141_25609_2 1042377.AFPJ01000043_gene940 1.34e-25 100.0 COG0745@1|root,COG0745@2|Bacteria,1RA00@1224|Proteobacteria,1S23N@1236|Gammaproteobacteria,466JJ@72275|Alteromonadaceae 1236|Gammaproteobacteria KT Transcriptional regulatory protein, C terminal - - - - - - - - - - - - Response_reg,Trans_reg_C k141_19589_1 1453501.JELR01000002_gene488 5.75e-30 115.0 COG3221@1|root,COG3221@2|Bacteria,1R5AU@1224|Proteobacteria,1RS4Z@1236|Gammaproteobacteria,4682S@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG3221 ABC-type phosphate phosphonate transport system, periplasmic component - - - - - - - - - - - - NMT1,Phosphonate-bd k141_11323_1 218284.CCDN010000001_gene1039 6.15e-135 390.0 COG1015@1|root,COG1015@2|Bacteria,1TP70@1239|Firmicutes,4H9RU@91061|Bacilli,1ZBG0@1386|Bacillus 91061|Bacilli G Phosphotransfer between the C1 and C5 carbon atoms of pentose deoB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008973,GO:0009987,GO:0016853,GO:0016866,GO:0016868,GO:0034641,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360 5.4.2.7 ko:K01839 ko00030,ko00230,map00030,map00230 - R01057,R02749 RC00408 ko00000,ko00001,ko01000 - - - Metalloenzyme k141_35038_1 218284.CCDN010000006_gene3621 6.15e-73 245.0 COG0745@1|root,COG5000@1|root,COG5002@1|root,COG0745@2|Bacteria,COG5000@2|Bacteria,COG5002@2|Bacteria,1U7NI@1239|Firmicutes,4HA3E@91061|Bacilli,1ZCFX@1386|Bacillus 91061|Bacilli T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - GAF,GAF_3,HAMP,HATPase_c,HisKA,Response_reg k141_36083_1 1116375.VEJY3_18116 1.39e-135 387.0 COG3384@1|root,COG3384@2|Bacteria,1MW77@1224|Proteobacteria,1RQIK@1236|Gammaproteobacteria,1XX4P@135623|Vibrionales 135623|Vibrionales S Catalytic LigB subunit of aromatic ring-opening dioxygenase - - 1.13.11.8 ko:K04101 ko00362,ko00624,ko00627,ko01120,map00362,map00624,map00627,map01120 - R01632,R03550,R04280,R09565 RC00233,RC00387,RC00535,RC02567,RC02694 br01602,ko00000,ko00001,ko01000 - - - LigB k141_7603_1 265729.GS18_0207280 1.23e-116 352.0 COG1874@1|root,COG1874@2|Bacteria,1TQN6@1239|Firmicutes,4HARI@91061|Bacilli,1ZCHT@1386|Bacillus 91061|Bacilli G beta-galactosidase - - 3.2.1.23 ko:K12308 ko00052,map00052 - R01105 RC00452 ko00000,ko00001,ko01000 - - - Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M k141_15956_1 315730.BcerKBAB4_3447 3.5e-36 125.0 2EAAJ@1|root,334EW@2|Bacteria,1VHS4@1239|Firmicutes,4HQYC@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - k141_30120_1 1453501.JELR01000002_gene1450 1.41e-67 209.0 COG1595@1|root,COG1595@2|Bacteria,1N2DR@1224|Proteobacteria,1S7D6@1236|Gammaproteobacteria,467MI@72275|Alteromonadaceae 1236|Gammaproteobacteria K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_30120_2 1279017.AQYJ01000027_gene2012 9.88e-70 213.0 COG1764@1|root,COG1764@2|Bacteria,1RD1A@1224|Proteobacteria,1S3UA@1236|Gammaproteobacteria,467CA@72275|Alteromonadaceae 1236|Gammaproteobacteria O redox protein, regulator of disulfide bond formation ohr - - - - - - - - - - - OsmC k141_30120_3 1279017.AQYJ01000027_gene2008 3.99e-196 547.0 COG0010@1|root,COG0010@2|Bacteria,1NCRN@1224|Proteobacteria,1RNKI@1236|Gammaproteobacteria,464I8@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide hutG GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016813,GO:0019439,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0052803,GO:0052805,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.3.11,3.5.3.8 ko:K01479,ko:K01480 ko00330,ko00340,ko01100,map00330,map00340,map01100 M00045,M00133 R01157,R02285 RC00024,RC00221,RC00329,RC00681 ko00000,ko00001,ko00002,ko01000 - - - Arginase k141_30120_4 1279017.AQYJ01000027_gene2007 4.43e-259 714.0 COG1228@1|root,COG1228@2|Bacteria,1MUYR@1224|Proteobacteria,1RMI9@1236|Gammaproteobacteria,464FR@72275|Alteromonadaceae 1236|Gammaproteobacteria Q COG1228 Imidazolonepropionase and related amidohydrolases hutI - 3.5.2.7 ko:K01468 ko00340,ko01100,map00340,map01100 M00045 R02288 RC00683 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1,Amidohydro_3 k141_30120_5 1279017.AQYJ01000027_gene2005 5.69e-122 353.0 COG2188@1|root,COG2188@2|Bacteria,1MVFM@1224|Proteobacteria,1RNPE@1236|Gammaproteobacteria,466EK@72275|Alteromonadaceae 1236|Gammaproteobacteria K histidine utilization repressor hutC - - ko:K05836 - - - - ko00000,ko03000 - - - GntR,UTRA k141_30120_6 1453501.JELR01000002_gene1454 0.0 1087.0 COG2987@1|root,COG2987@2|Bacteria,1MU4W@1224|Proteobacteria,1RP89@1236|Gammaproteobacteria,46644@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate hutU GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016153,GO:0016829,GO:0016835,GO:0016836,GO:0019439,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0052803,GO:0052805,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 4.2.1.49 ko:K01712 ko00340,ko01100,map00340,map01100 M00045 R02914 RC00804 ko00000,ko00001,ko00002,ko01000 - - - Urocanase,Urocanase_C,Urocanase_N k141_30120_7 1279017.AQYJ01000027_gene2003 8.06e-317 870.0 COG2986@1|root,COG2986@2|Bacteria,1MU6K@1224|Proteobacteria,1RP02@1236|Gammaproteobacteria,464VI@72275|Alteromonadaceae 1236|Gammaproteobacteria E Histidine ammonia-lyase hutH GO:0003674,GO:0003824,GO:0004397,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016840,GO:0016841,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564 4.3.1.3 ko:K01745 ko00340,ko01100,map00340,map01100 M00045 R01168 RC00361 ko00000,ko00001,ko00002,ko01000 - - - Lyase_aromatic k141_30120_9 1453501.JELR01000002_gene1386 2.19e-120 350.0 COG1028@1|root,COG1028@2|Bacteria,1MU5Y@1224|Proteobacteria,1RP7D@1236|Gammaproteobacteria,46633@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) bdhA - 1.1.1.30 ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 M00088 R01361 RC00117 ko00000,ko00001,ko00002,ko01000 - - - adh_short,adh_short_C2 k141_30120_10 1453501.JELR01000002_gene1385 2.35e-108 317.0 COG2197@1|root,COG2197@2|Bacteria,1PXTY@1224|Proteobacteria,1RMPW@1236|Gammaproteobacteria,466JI@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain agmR - - ko:K07684 ko02020,map02020 M00471 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg k141_30120_11 1042377.AFPJ01000043_gene824 1.94e-158 451.0 COG0657@1|root,COG0657@2|Bacteria,1NEXK@1224|Proteobacteria,1RYVV@1236|Gammaproteobacteria 1236|Gammaproteobacteria I alpha/beta hydrolase fold - - - ko:K01066 - - - - ko00000,ko01000 - - - Abhydrolase_3,PNP_UDP_1 k141_30120_12 1453501.JELR01000002_gene1383 1.33e-222 621.0 COG2807@1|root,COG2807@2|Bacteria,1R9ET@1224|Proteobacteria,1RS3X@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Major facilitator superfamily - - - - - - - - - - - - MFS_1 k141_30120_13 1042377.AFPJ01000038_gene1099 3.76e-288 825.0 COG0591@1|root,COG0642@1|root,COG0784@1|root,COG0591@2|Bacteria,COG0784@2|Bacteria,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,1RP2U@1236|Gammaproteobacteria,465DY@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0591 Na proline symporter - - - - - - - - - - - - HATPase_c,HisKA,PAS_7,Response_reg,SSF k141_32689_2 1294265.JCM21738_145 2.52e-43 145.0 COG0340@1|root,COG0340@2|Bacteria,1TQCU@1239|Firmicutes,4HB60@91061|Bacilli,1ZBI9@1386|Bacillus 91061|Bacilli K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor birA - 6.3.4.15 ko:K03524 ko00780,ko01100,map00780,map01100 - R01074,R05145 RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko01000,ko03000 - - - BPL_C,BPL_LplA_LipB,HTH_11 k141_7780_2 1279017.AQYJ01000022_gene2591 8.09e-30 111.0 COG2905@1|root,COG2905@2|Bacteria,1R0M0@1224|Proteobacteria,1T4K3@1236|Gammaproteobacteria,46DE1@72275|Alteromonadaceae 1236|Gammaproteobacteria T Cyclic nucleotide-monophosphate binding domain - - - - - - - - - - - - cNMP_binding k141_22097_1 223926.28807889 1.05e-63 207.0 COG1027@1|root,COG1027@2|Bacteria,1R9JY@1224|Proteobacteria,1RP5Z@1236|Gammaproteobacteria,1XSMK@135623|Vibrionales 135623|Vibrionales E Aspartate ammonia-lyase aspA - 4.3.1.1 ko:K01744 ko00250,ko01100,map00250,map01100 - R00490 RC00316,RC02799 ko00000,ko00001,ko01000 - - - FumaraseC_C,Lyase_1 k141_22097_2 1280001.BAOA01000011_gene4254 6.48e-24 99.4 COG2704@1|root,COG2704@2|Bacteria,1MVHH@1224|Proteobacteria,1RPTE@1236|Gammaproteobacteria,1XT7X@135623|Vibrionales 135623|Vibrionales S Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane dcuA - - ko:K07791 - - - - ko00000,ko02000 2.A.13.1 - - DcuA_DcuB k141_9130_1 1453501.JELR01000002_gene1384 4.87e-24 98.2 COG0657@1|root,COG0657@2|Bacteria,1RD8A@1224|Proteobacteria,1S3TH@1236|Gammaproteobacteria,4687P@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG0657 Esterase lipase - - 3.1.1.83,3.1.1.85 ko:K14731,ko:K19561 ko00780,ko00903,ko00930,ko01100,ko01220,map00780,map00903,map00930,map01100,map01220 M00572 R03751,R06390,R06391,R06392,R06393,R09725 RC00460,RC00461,RC00713,RC00983,RC01505 ko00000,ko00001,ko00002,ko01000 - - - Abhydrolase_3 k141_29213_1 1280001.BAOA01000021_gene730 5.81e-221 613.0 COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,1RMVW@1236|Gammaproteobacteria,1XTZN@135623|Vibrionales 135623|Vibrionales C Belongs to the UDP-glucose GDP-mannose dehydrogenase family ugd - 1.1.1.22 ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 M00014,M00129,M00361,M00362 R00286 RC00291 ko00000,ko00001,ko00002,ko01000 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N k141_4267_1 1196029.ALIM01000014_gene2948 1.51e-08 55.5 COG0581@1|root,COG0581@2|Bacteria,1TP74@1239|Firmicutes,4HAKF@91061|Bacilli,1ZDAY@1386|Bacillus 91061|Bacilli P Phosphate transport system permease pstA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02038 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 k141_4267_2 218284.CCDN010000001_gene789 3.04e-158 448.0 COG0573@1|root,COG0573@2|Bacteria,1TSPP@1239|Firmicutes,4HC9H@91061|Bacilli,1ZAUU@1386|Bacillus 91061|Bacilli P probably responsible for the translocation of the substrate across the membrane pstC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02037 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 k141_27153_1 1219077.VAZ01S_031_00570 1.08e-19 87.0 COG1043@1|root,COG1043@2|Bacteria,1MUHQ@1224|Proteobacteria,1RPHB@1236|Gammaproteobacteria,1XSN6@135623|Vibrionales 135623|Vibrionales M Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxA GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0008654,GO:0008780,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.129 ko:K00677 ko00540,ko01100,ko01503,map00540,map01100,map01503 M00060 R04567 RC00039,RC00055 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Acetyltransf_11,Hexapep k141_27153_2 672.VV93_v1c22650 4.73e-100 290.0 COG0764@1|root,COG0764@2|Bacteria,1RH2T@1224|Proteobacteria,1S63E@1236|Gammaproteobacteria,1XVJ6@135623|Vibrionales 135623|Vibrionales I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs fabZ GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 4.2.1.59 ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121 RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FabA k141_27153_3 1116375.VEJY3_12025 1.36e-157 452.0 COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,1RNYI@1236|Gammaproteobacteria,1XSDH@135623|Vibrionales 135623|Vibrionales I Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxD GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 ko:K02536 ko00540,ko01100,map00540,map01100 M00060 R04550 RC00039,RC00166 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Hexapep,Hexapep_2,LpxD k141_27153_4 1116375.VEJY3_12030 8.49e-99 290.0 COG2825@1|root,COG2825@2|Bacteria,1RD8X@1224|Proteobacteria,1RQIE@1236|Gammaproteobacteria,1XUST@135623|Vibrionales 135623|Vibrionales M Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm skp GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - ko:K06142 - - - - ko00000 - - - OmpH k141_27153_5 1116375.VEJY3_12035 0.0 1568.0 COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,1RMAP@1236|Gammaproteobacteria,1XTPE@135623|Vibrionales 135623|Vibrionales M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamA - - ko:K07277 - - - - ko00000,ko02000,ko03029 1.B.33 - - Bac_surface_Ag,POTRA k141_27153_6 1116375.VEJY3_12040 8.54e-304 831.0 COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,1RMIX@1236|Gammaproteobacteria,1XUCN@135623|Vibrionales 135623|Vibrionales M Zinc metalloprotease rseP - - ko:K11749 ko02024,ko04112,map02024,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - PDZ,PDZ_2,Peptidase_M50 k141_27153_7 1116375.VEJY3_12045 1.43e-177 501.0 COG0743@1|root,COG0743@2|Bacteria,1MU4G@1224|Proteobacteria,1RNNW@1236|Gammaproteobacteria,1XT3U@135623|Vibrionales 135623|Vibrionales I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) dxr GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05688 RC01452 ko00000,ko00001,ko00002,ko01000 - - - DXPR_C,DXP_redisom_C,DXP_reductoisom k141_10375_2 1294265.JCM21738_2254 1.04e-140 401.0 COG0115@1|root,COG0115@2|Bacteria,1TPY2@1239|Firmicutes,4HAWW@91061|Bacilli,1ZBVX@1386|Bacillus 91061|Bacilli E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction dat GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016769,GO:0019478,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0046416,GO:0046437,GO:0047810,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.6.1.21 ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 - R01148,R01582,R02459,R02851,R02924,R05053 RC00006,RC00008,RC00025 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_4 k141_17315_1 1042377.AFPJ01000034_gene2336 1.87e-221 616.0 COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,1RN91@1236|Gammaproteobacteria,46522@72275|Alteromonadaceae 1236|Gammaproteobacteria M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine murA GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008760,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R00660 RC00350 ko00000,ko00001,ko01000,ko01011 - - - EPSP_synthase k141_17315_2 1042377.AFPJ01000034_gene2337 1.13e-119 345.0 COG0040@1|root,COG0040@2|Bacteria,1MUCY@1224|Proteobacteria,1RNAX@1236|Gammaproteobacteria,46649@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity hisG - 2.4.2.17 ko:K00765 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002,ko01000 - - - HisG k141_24515_2 218284.CCDN010000005_gene3480 5.85e-87 260.0 COG1670@1|root,COG1670@2|Bacteria,1V2C6@1239|Firmicutes,4HG3C@91061|Bacilli,1ZHB2@1386|Bacillus 91061|Bacilli J Acetyltransferase (GNAT) domain - - 2.3.1.128 ko:K03790 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 k141_32691_1 1294265.JCM21738_4813 4.83e-97 294.0 COG0840@1|root,COG0840@2|Bacteria,1UVY9@1239|Firmicutes,4HB1T@91061|Bacilli,1ZD8I@1386|Bacillus 91061|Bacilli NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). yvaQ - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal k141_11560_1 981327.F925_00847 9.94e-43 155.0 COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,1RMR2@1236|Gammaproteobacteria,3NKAA@468|Moraxellaceae 1236|Gammaproteobacteria G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate glmM GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006464,GO:0006468,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008966,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0018130,GO:0019438,GO:0019538,GO:0034641,GO:0034654,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0046777,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901576 5.4.2.10 ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 - R02060 RC00408 ko00000,ko00001,ko01000 - - iSBO_1134.SBO_3206 PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV k141_36228_1 450851.PHZ_c3127 1.5e-72 247.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,2TS65@28211|Alphaproteobacteria,2KEZ7@204458|Caulobacterales 204458|Caulobacterales P TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_29215_1 218284.CCDN010000002_gene2662 5.14e-124 363.0 COG1055@1|root,COG1055@2|Bacteria,1TPNN@1239|Firmicutes,4H9WV@91061|Bacilli,1ZBHC@1386|Bacillus 91061|Bacilli P Involved in arsenical resistance. Thought to form the channel of an arsenite pump ydfA - - ko:K03893 - - - - ko00000,ko02000 2.A.45.1,3.A.4.1 - - ArsB k141_37449_1 1294265.JCM21738_930 1.36e-151 439.0 COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HAHB@91061|Bacilli,1ZPZR@1386|Bacillus 91061|Bacilli IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II yngI - - ko:K00666 - - - - ko00000,ko01000,ko01004 - - - AMP-binding,AMP-binding_C k141_11561_1 1453501.JELR01000002_gene1155 2.24e-87 269.0 COG0025@1|root,COG0025@2|Bacteria,1MW5T@1224|Proteobacteria,1RPH6@1236|Gammaproteobacteria,464FP@72275|Alteromonadaceae 1236|Gammaproteobacteria P Sodium/hydrogen exchanger family nhaP - - ko:K03316 - - - - ko00000 2.A.36 - - Na_H_Exchanger k141_30264_1 218284.CCDN010000001_gene153 1.35e-159 459.0 COG0508@1|root,COG0508@2|Bacteria,1TR5N@1239|Firmicutes,4HA7A@91061|Bacilli,1ZAQR@1386|Bacillus 91061|Bacilli C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex pdhC - 2.3.1.12 ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding k141_6724_1 1173028.ANKO01000048_gene1149 3.21e-45 164.0 COG2304@1|root,COG2304@2|Bacteria,1GDDB@1117|Cyanobacteria,1HFF0@1150|Oscillatoriales 1117|Cyanobacteria S von Willebrand factor (vWF) type A domain - - - - - - - - - - - - - k141_16156_2 338966.Ppro_2303 1.4e-22 100.0 COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1MWKS@1224|Proteobacteria,42M1G@68525|delta/epsilon subdivisions,2WJ7V@28221|Deltaproteobacteria,43TCH@69541|Desulfuromonadales 28221|Deltaproteobacteria J TIGRFAM phenylalanyl-tRNA synthetase, beta subunit pheT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - B3_4,B5,FDX-ACB,tRNA_bind k141_17316_1 1294265.JCM21738_1464 1.14e-120 353.0 COG2235@1|root,COG2235@2|Bacteria,1TQWS@1239|Firmicutes,4HCMG@91061|Bacilli,1ZS3P@1386|Bacillus 91061|Bacilli E Arginine deiminase arcA - 3.5.3.6 ko:K01478 ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130 - R00552 RC00177 ko00000,ko00001,ko01000 - - - Amidinotransf k141_29216_1 218284.CCDN010000002_gene2230 1.5e-67 216.0 COG0654@1|root,COG0654@2|Bacteria,1U29G@1239|Firmicutes,4HF0P@91061|Bacilli,1ZE9I@1386|Bacillus 91061|Bacilli CH FAD binding domain - - - - - - - - - - - - FAD_binding_3 k141_14027_1 223926.28808696 3.75e-113 328.0 COG1296@1|root,COG1296@2|Bacteria,1MVGN@1224|Proteobacteria,1S2AK@1236|Gammaproteobacteria,1XSZ2@135623|Vibrionales 135623|Vibrionales E branched-chain amino acid permease (azaleucine resistance) - - - - - - - - - - - - AzlC k141_14027_2 1116375.VEJY3_21976 3.32e-125 359.0 COG1280@1|root,COG1280@2|Bacteria,1MWA1@1224|Proteobacteria,1SF3D@1236|Gammaproteobacteria,1XUB0@135623|Vibrionales 135623|Vibrionales E threonine efflux protein - - - - - - - - - - - - LysE k141_5619_1 1120963.KB894501_gene166 6.19e-14 65.1 2DR5Z@1|root,33ABB@2|Bacteria,1NIYJ@1224|Proteobacteria,1SGQ9@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_5619_2 29495.EA26_20560 5.84e-59 186.0 COG3335@1|root,COG3335@2|Bacteria,1RCFZ@1224|Proteobacteria,1S2QS@1236|Gammaproteobacteria,1XWK6@135623|Vibrionales 135623|Vibrionales L DDE superfamily endonuclease - - - - - - - - - - - - DDE_3 k141_9133_1 218284.CCDN010000007_gene3800 5.59e-140 398.0 COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,4HAYM@91061|Bacilli,1ZBXG@1386|Bacillus 91061|Bacilli D COG1192 ATPases involved in chromosome partitioning soj GO:0008150,GO:0022603,GO:0042173,GO:0042174,GO:0043937,GO:0043939,GO:0045595,GO:0045596,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0065007 - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 k141_4268_1 1196031.ALEG01000068_gene4829 4.22e-05 44.7 COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,4H9Q8@91061|Bacilli,1ZBRE@1386|Bacillus 91061|Bacilli D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase tig GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K03545 - - - - ko00000 - - - FKBP_C,Trigger_C,Trigger_N k141_34031_1 1173020.Cha6605_2404 1.51e-33 125.0 COG3453@1|root,COG3453@2|Bacteria,1G6UU@1117|Cyanobacteria 1117|Cyanobacteria S phosphatase (DUF442) - - - - - - - - - - - - DUF442 k141_34031_2 1535422.ND16A_2580 3.88e-53 171.0 COG0454@1|root,COG0456@2|Bacteria,1N506@1224|Proteobacteria,1S97J@1236|Gammaproteobacteria 1236|Gammaproteobacteria K PFAM GCN5-related N-acetyltransferase - - - - - - - - - - - - Acetyltransf_1 k141_34031_3 1279017.AQYJ01000028_gene2137 4.86e-85 279.0 COG0308@1|root,COG0308@2|Bacteria,1PJTM@1224|Proteobacteria,1SYS3@1236|Gammaproteobacteria,4672R@72275|Alteromonadaceae 1236|Gammaproteobacteria E Peptidase family M1 domain - - 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - ERAP1_C,Peptidase_M1 k141_23453_2 218284.CCDN010000001_gene1851 4.41e-69 224.0 COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1TSSC@1239|Firmicutes,4HA8C@91061|Bacilli,1ZBA6@1386|Bacillus 91061|Bacilli C COG1014 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, gamma subunit korA - 1.2.7.11,1.2.7.3 ko:K00174 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - PFOR_II,POR,POR_N k141_24518_1 42565.FP66_15515 1.53e-93 277.0 COG0670@1|root,COG0670@2|Bacteria,1MU69@1224|Proteobacteria,1RRVZ@1236|Gammaproteobacteria,1XJTV@135619|Oceanospirillales 135619|Oceanospirillales S Belongs to the BI1 family - - - ko:K19416 - M00742 - - ko00000,ko00002,ko02000 1.A.14.2.1 - - Bax1-I k141_22099_1 1441930.Z042_04755 1.17e-18 90.5 COG3290@1|root,COG3447@1|root,COG5001@1|root,COG3290@2|Bacteria,COG3447@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1T2FD@1236|Gammaproteobacteria,4001B@613|Serratia 1236|Gammaproteobacteria T Diguanylate cyclase - - 2.7.7.65 ko:K21084 ko02026,map02026 - - - ko00000,ko00001,ko01000 - - - EAL,GGDEF,MASE1,PAS,PAS_3,PAS_4 k141_22099_2 1279017.AQYJ01000023_gene3124 1.94e-142 424.0 COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,465W3@72275|Alteromonadaceae 1236|Gammaproteobacteria T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - GAF_2,HAMP,HATPase_c,HisKA,Hpt,NMT1,PAS,PAS_3,PAS_4,PAS_9,Response_reg k141_6726_1 218284.CCDN010000006_gene3572 8.38e-72 234.0 COG4264@1|root,COG4264@2|Bacteria,1TSC3@1239|Firmicutes,4HDUE@91061|Bacilli,1ZQIZ@1386|Bacillus 91061|Bacilli Q IucA / IucC family - - - - - - - - - - - - FhuF,IucA_IucC k141_20842_1 1120949.KB903295_gene2277 7.94e-05 50.1 COG0577@1|root,COG0577@2|Bacteria,2GIRW@201174|Actinobacteria,4DGYT@85008|Micromonosporales 201174|Actinobacteria V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD k141_5620_1 218284.CCDN010000004_gene3051 1.09e-15 73.6 COG0398@1|root,COG0398@2|Bacteria,1V3J1@1239|Firmicutes,4HHXX@91061|Bacilli,1ZEPX@1386|Bacillus 91061|Bacilli S SNARE associated Golgi protein ytxB - - - - - - - - - - - SNARE_assoc k141_5620_2 218284.CCDN010000004_gene3050 4.49e-119 342.0 COG0558@1|root,COG0558@2|Bacteria,1V33A@1239|Firmicutes,4HA26@91061|Bacilli,1ZDZZ@1386|Bacillus 91061|Bacilli I CDP-alcohol phosphatidyltransferase - - - - - - - - - - - - CDP-OH_P_transf k141_9134_1 42565.FP66_08695 1.09e-214 608.0 COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,1RMAH@1236|Gammaproteobacteria,1XHC0@135619|Oceanospirillales 135619|Oceanospirillales E Oligopeptidase prlC - 3.4.24.70 ko:K01414 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M3 k141_7785_1 1158294.JOMI01000002_gene3155 9.75e-27 104.0 2DN97@1|root,32W7A@2|Bacteria,4P5E4@976|Bacteroidetes,2FTS2@200643|Bacteroidia 976|Bacteroidetes - - - - - - - - - - - - - - - k141_844_1 935836.JAEL01000155_gene1429 3.01e-83 259.0 COG0019@1|root,COG0019@2|Bacteria,1TPE9@1239|Firmicutes,4H9XW@91061|Bacilli,1ZD43@1386|Bacillus 91061|Bacilli E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine lysA - 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N,Orn_DAP_Arg_deC k141_6727_1 1461580.CCAS010000023_gene2409 3.78e-98 301.0 COG3039@1|root,COG3039@2|Bacteria,1TPFS@1239|Firmicutes,4HD09@91061|Bacilli,1ZEKY@1386|Bacillus 91061|Bacilli L COG3039 Transposase and inactivated derivatives, IS5 family - - - - - - - - - - - - DDE_Tnp_1,DDE_Tnp_1_6,DUF772 k141_37451_1 357808.RoseRS_4193 1.28e-19 89.4 COG1012@1|root,COG1012@2|Bacteria,2G5JZ@200795|Chloroflexi,375DB@32061|Chloroflexia 32061|Chloroflexia C Belongs to the aldehyde dehydrogenase family - - - - - - - - - - - - Aldedh k141_31416_1 1116375.VEJY3_18236 2.21e-96 283.0 COG0454@1|root,COG0456@2|Bacteria,1RBE6@1224|Proteobacteria,1S916@1236|Gammaproteobacteria,1XX22@135623|Vibrionales 135623|Vibrionales K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10 k141_5621_1 498211.CJA_1140 1.07e-81 270.0 COG1472@1|root,COG2755@1|root,COG1472@2|Bacteria,COG2755@2|Bacteria,1MVIV@1224|Proteobacteria,1RMA0@1236|Gammaproteobacteria,1FIIP@10|Cellvibrio 1236|Gammaproteobacteria EG Glycosyl hydrolase family 3 C-terminal domain - - 3.2.1.21 ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 - R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - GH3 - CBM_6,Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C,Lipase_GDSL_2 k141_14935_1 218284.CCDN010000006_gene3615 1.52e-108 322.0 COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,4H9R3@91061|Bacilli,1ZCXW@1386|Bacillus 91061|Bacilli F Belongs to the phosphoglycerate kinase family pgk GO:0001871,GO:0002020,GO:0003674,GO:0003824,GO:0004618,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009893,GO:0009986,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019222,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030162,GO:0030193,GO:0030195,GO:0030246,GO:0030247,GO:0030312,GO:0031323,GO:0031325,GO:0032101,GO:0032102,GO:0032268,GO:0032270,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043532,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0045862,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048518,GO:0048519,GO:0048522,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050818,GO:0050819,GO:0050878,GO:0051171,GO:0051173,GO:0051186,GO:0051188,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051917,GO:0051919,GO:0055086,GO:0060255,GO:0061041,GO:0061045,GO:0065007,GO:0065008,GO:0070613,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0080134,GO:0090407,GO:1900046,GO:1900047,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903034,GO:1903035,GO:1903317,GO:1903319,GO:2001065 2.7.2.3 ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01512 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000,ko04147 - - iSB619.SA_RS04145 PGK k141_14935_2 218284.CCDN010000006_gene3614 2.77e-54 176.0 COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,4HAPT@91061|Bacilli,1ZB6N@1386|Bacillus 91061|Bacilli G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) tpiA GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01015 RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 - - - TIM k141_25851_2 1279017.AQYJ01000022_gene2735 2.77e-254 701.0 COG3825@1|root,COG3825@2|Bacteria,1MUAJ@1224|Proteobacteria,1RMRY@1236|Gammaproteobacteria,464I9@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria IV02_28405 - - ko:K09989 - - - - ko00000 - - - VWA_CoxE k141_19789_2 314287.GB2207_11278 3.67e-49 171.0 COG0015@1|root,COG0015@2|Bacteria,1MXNN@1224|Proteobacteria,1RS00@1236|Gammaproteobacteria,1J9YW@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria F Adenylosuccinate lyase C-terminus - - 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 - - - ADSL_C,Lyase_1 k141_23468_2 1453501.JELR01000001_gene2663 7.04e-95 278.0 29AX6@1|root,2ZXWB@2|Bacteria,1RE7P@1224|Proteobacteria,1S52J@1236|Gammaproteobacteria,467ER@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_27906_1 589865.DaAHT2_2115 6.11e-06 55.1 COG2864@1|root,COG2864@2|Bacteria,1NJEJ@1224|Proteobacteria,42NQM@68525|delta/epsilon subdivisions,2WK76@28221|Deltaproteobacteria 28221|Deltaproteobacteria C denitrification pathway - - - - - - - - - - - - Ni_hydr_CYTB k141_29230_1 1042377.AFPJ01000055_gene960 1.92e-79 254.0 COG5653@1|root,COG5653@2|Bacteria,1RAB9@1224|Proteobacteria,1SKTJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_6 k141_29230_2 1479237.JMLY01000001_gene3195 2.85e-149 427.0 COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,1RTDE@1236|Gammaproteobacteria,464ZV@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG0846 NAD-dependent protein deacetylases, SIR2 family cobB - - ko:K12410 - - - - ko00000,ko01000 - - - SIR2 k141_29230_3 1288826.MSNKSG1_10388 0.0 954.0 COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,1RPIW@1236|Gammaproteobacteria,46464@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Amidohydrolase family - - - - - - - - - - - - Amidohydro_1,Amidohydro_3 k141_29230_5 1040989.AWZU01000025_gene6305 2.53e-19 85.5 COG4319@1|root,COG4319@2|Bacteria,1RF3Q@1224|Proteobacteria,2U78H@28211|Alphaproteobacteria,3JZ1D@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S SnoaL-like domain - - - - - - - - - - - - DUF4440 k141_29230_6 1496688.ER33_02825 1.3e-61 209.0 COG3675@1|root,COG3675@2|Bacteria,1G7WY@1117|Cyanobacteria,22TH3@167375|Cyanobium 1117|Cyanobacteria I Lipase (class 3) - - 3.1.1.3 ko:K01046 ko00561,ko01100,map00561,map01100 M00098 R02250,R02687 RC00020,RC00037,RC00041,RC00094 ko00000,ko00001,ko00002,ko01000 - - - Lipase_3 k141_29230_8 1279017.AQYJ01000022_gene2629 1.62e-113 329.0 COG2878@1|root,COG2878@2|Bacteria,1MUWU@1224|Proteobacteria,1RNSJ@1236|Gammaproteobacteria,464VR@72275|Alteromonadaceae 1236|Gammaproteobacteria C Part of a membrane complex involved in electron transport rnfB GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0055114 - ko:K03616 - - - - ko00000 - - - FeS,Fer4_21 k141_7809_1 997296.PB1_15144 2.91e-159 463.0 COG0358@1|root,COG0358@2|Bacteria,1TQ0X@1239|Firmicutes,4HAG2@91061|Bacilli,1ZC16@1386|Bacillus 91061|Bacilli L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG - - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2 k141_16171_1 991905.SL003B_1031 8.33e-72 232.0 COG0845@1|root,COG0845@2|Bacteria,1Q112@1224|Proteobacteria,2V906@28211|Alphaproteobacteria,4BSRF@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K02005 - - - - ko00000 - - - HlyD_3 k141_16171_2 749414.SBI_08836 3.87e-05 48.5 COG1028@1|root,COG1028@2|Bacteria,2GK20@201174|Actinobacteria 201174|Actinobacteria IQ Short-chain dehydrogenase reductase sdr gno - 1.1.1.100,1.1.1.127,1.1.1.69 ko:K00046,ko:K00059,ko:K00065 ko00040,ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00040,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R01542,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00089,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 k141_9168_1 997296.PB1_09352 3.32e-63 201.0 COG2177@1|root,COG2177@2|Bacteria,1TPND@1239|Firmicutes,4HA5A@91061|Bacilli,1ZC4Q@1386|Bacillus 91061|Bacilli D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation ftsX GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0007154,GO:0007165,GO:0007166,GO:0008150,GO:0008356,GO:0009966,GO:0009987,GO:0010033,GO:0010646,GO:0016020,GO:0016043,GO:0019221,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0023052,GO:0032506,GO:0034097,GO:0042173,GO:0042221,GO:0043937,GO:0043938,GO:0044085,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051301,GO:0051716,GO:0065007,GO:0070098,GO:0070297,GO:0070887,GO:0071310,GO:0071345,GO:0071840,GO:0071944,GO:0090529,GO:1902531 - ko:K09811 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - FtsX k141_14061_1 98439.AJLL01000068_gene1520 5.59e-49 177.0 COG5001@1|root,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria,1JGRR@1189|Stigonemataceae 1117|Cyanobacteria T Putative diguanylate phosphodiesterase - - - - - - - - - - - - EAL,FHA,GAF,GGDEF,PAS_9 k141_22127_1 574966.KB898647_gene2543 6.29e-55 176.0 COG1335@1|root,COG1335@2|Bacteria,1MWFQ@1224|Proteobacteria,1RMHF@1236|Gammaproteobacteria,1XNVY@135619|Oceanospirillales 135619|Oceanospirillales Q COG1335 Amidases related to nicotinamidase - - - - - - - - - - - - Isochorismatase k141_22127_2 414684.RC1_3008 3.45e-23 101.0 2C5U9@1|root,2Z8KT@2|Bacteria,1N30S@1224|Proteobacteria 1224|Proteobacteria S Bacterial protein of unknown function (Gcw_chp) - - - - - - - - - - - - Gcw_chp k141_22127_3 1380387.JADM01000001_gene374 7.35e-265 735.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,1XIMQ@135619|Oceanospirillales 135619|Oceanospirillales C Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid betB - 1.2.1.8 ko:K00130 ko00260,ko01100,map00260,map01100 M00555 R02565,R02566 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_22127_4 570967.JMLV01000019_gene383 0.0 918.0 COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,2TQKQ@28211|Alphaproteobacteria,2JPPV@204441|Rhodospirillales 204441|Rhodospirillales E Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - 1.1.99.1 ko:K00108 ko00260,ko01100,map00260,map01100 M00555 R01025 RC00087 ko00000,ko00001,ko00002,ko01000 - - - GMC_oxred_C,GMC_oxred_N k141_22127_5 1380387.JADM01000001_gene376 0.0 974.0 COG1292@1|root,COG1292@2|Bacteria,1MV0K@1224|Proteobacteria,1RP3E@1236|Gammaproteobacteria,1XN46@135619|Oceanospirillales 135619|Oceanospirillales M BCCT, betaine/carnitine/choline family transporter - - - ko:K02168 - - - - ko00000,ko02000 2.A.15.1.3,2.A.15.1.4 - - BCCT k141_18753_1 1453501.JELR01000002_gene349 5.08e-133 408.0 COG4105@1|root,COG4105@2|Bacteria,1QVQ9@1224|Proteobacteria,1RSIG@1236|Gammaproteobacteria,46DC5@72275|Alteromonadaceae 1236|Gammaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16,TPR_6 k141_11583_1 218284.CCDN010000002_gene2379 8.19e-40 135.0 2DZYA@1|root,32VN2@2|Bacteria,1VA7J@1239|Firmicutes,4HKH0@91061|Bacilli,1ZF7X@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_9169_1 218284.CCDN010000001_gene88 1.06e-95 292.0 COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,4H9T1@91061|Bacilli,1ZB77@1386|Bacillus 91061|Bacilli M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan murE GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 ko:K01928 ko00300,ko00550,map00300,map00550 - R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M k141_863_1 1117647.M5M_07705 6.32e-25 104.0 COG0154@1|root,COG0154@2|Bacteria,1MW3Z@1224|Proteobacteria,1RP33@1236|Gammaproteobacteria,1J6AR@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases - - 3.5.1.4 ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 - R02540,R03096,R03180,R03909,R05551,R05590 RC00010,RC00100,RC00950,RC01025 ko00000,ko00001,ko01000 - - - Amidase k141_863_2 1042377.AFPJ01000042_gene1013 1.22e-35 129.0 COG4336@1|root,COG4336@2|Bacteria,1MW52@1224|Proteobacteria,1RN4P@1236|Gammaproteobacteria,463YD@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the D-glutamate cyclase family - - - - - - - - - - - - DUF1445 k141_20858_1 218284.CCDN010000001_gene1848 1.17e-52 176.0 COG3291@1|root,COG3291@2|Bacteria,1V7H2@1239|Firmicutes,4HIX2@91061|Bacilli,1ZDRV@1386|Bacillus 91061|Bacilli S Pkd domain containing protein - - - - - - - - - - - - - k141_30282_1 251221.35211608 1.39e-94 287.0 COG1899@1|root,COG1899@2|Bacteria,1G448@1117|Cyanobacteria 1117|Cyanobacteria O Belongs to the deoxyhypusine synthase family - - 2.5.1.46 ko:K00809 - - - - ko00000,ko01000 - - - DS k141_36244_1 218284.CCDN010000004_gene3042 3.32e-139 406.0 COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,4HAB3@91061|Bacilli,1ZAPP@1386|Bacillus 91061|Bacilli JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity cshA GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 3.6.4.13 ko:K05592 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,Helicase_C k141_1825_1 218284.CCDN010000006_gene3514 1.43e-135 405.0 COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1TR8J@1239|Firmicutes,4H9XN@91061|Bacilli,1ZATV@1386|Bacillus 91061|Bacilli I 3-hydroxyacyl-CoA dehydrogenase fadN - 1.1.1.35 ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 M00087 R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU32840 3HCDH,3HCDH_N,ECH_1 k141_5748_1 997296.PB1_06697 5e-204 597.0 COG0085@1|root,COG0085@2|Bacteria,1TP96@1239|Firmicutes,4H9PK@91061|Bacilli,1ZBPC@1386|Bacillus 91061|Bacilli K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoB GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 k141_20953_1 218284.CCDN010000001_gene1893 4.81e-175 528.0 COG2176@1|root,COG2176@2|Bacteria,1TPAG@1239|Firmicutes,4H9RF@91061|Bacilli,1ZCIB@1386|Bacillus 91061|Bacilli L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity polC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.7.7 ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_a_NI,DNA_pol3_a_NII,DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon k141_1914_2 42565.FP66_13655 3.36e-83 254.0 COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,1RPSV@1236|Gammaproteobacteria,1XJWQ@135619|Oceanospirillales 135619|Oceanospirillales F Belongs to the ATCase OTCase family pyrB - 2.1.3.2 ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N k141_26008_1 1453501.JELR01000002_gene955 1.41e-72 219.0 COG0745@1|root,COG0745@2|Bacteria,1RI9T@1224|Proteobacteria,1S5UT@1236|Gammaproteobacteria,467AE@72275|Alteromonadaceae 1236|Gammaproteobacteria KT COG0784 FOG CheY-like receiver pilH - - ko:K02658 ko02020,ko02025,map02020,map02025 M00507 - - ko00000,ko00001,ko00002,ko02022,ko02035,ko02044 - - - Response_reg k141_26008_2 1042377.AFPJ01000032_gene2821 3.29e-101 296.0 COG0835@1|root,COG0835@2|Bacteria,1RCIR@1224|Proteobacteria,1S61F@1236|Gammaproteobacteria,467KR@72275|Alteromonadaceae 1236|Gammaproteobacteria NT COG0835 Chemotaxis signal transduction protein pilI - - ko:K02659 ko02020,ko02025,map02020,map02025 - - - ko00000,ko00001,ko02035,ko02044 - - - CheW k141_11740_1 1279017.AQYJ01000025_gene764 4.03e-83 256.0 COG2515@1|root,COG2515@2|Bacteria,1RHDE@1224|Proteobacteria,1S7AT@1236|Gammaproteobacteria,46CKN@72275|Alteromonadaceae 1236|Gammaproteobacteria E Pyridoxal-phosphate dependent enzyme - - 3.5.99.7 ko:K01505 ko00270,map00270 - R00997 RC00419 ko00000,ko00001,ko01000 - - - PALP k141_6982_2 223926.28806568 2.56e-170 476.0 COG0433@1|root,COG0433@2|Bacteria,1N9XI@1224|Proteobacteria,1SCPX@1236|Gammaproteobacteria,1XVVG@135623|Vibrionales 135623|Vibrionales S COG0433 Predicted ATPase VP1577 - - - - - - - - - - - - k141_6982_3 1116375.VEJY3_07465 1.14e-34 122.0 2AWES@1|root,31NAV@2|Bacteria,1QK1X@1224|Proteobacteria,1TI4G@1236|Gammaproteobacteria,1XYCT@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_23719_2 218284.CCDN010000007_gene3868 1.31e-100 296.0 294NZ@1|root,2ZS2A@2|Bacteria,1V3ME@1239|Firmicutes,4HHEZ@91061|Bacilli,1ZFT3@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_23719_3 1526927.Plano_1463 5.89e-99 300.0 COG0531@1|root,COG0531@2|Bacteria,1TVM4@1239|Firmicutes,4HP9X@91061|Bacilli,26H2U@186818|Planococcaceae 91061|Bacilli E Amino acid permease - - - - - - - - - - - - AA_permease_2 k141_37589_1 1294265.JCM21738_3704 9.13e-94 275.0 COG0839@1|root,COG0839@2|Bacteria,1V48R@1239|Firmicutes,4HJAV@91061|Bacilli,1ZFW1@1386|Bacillus 91061|Bacilli C Belongs to the complex I subunit 6 family nuoJ - 1.6.5.3 ko:K00339 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q3 k141_37589_2 935836.JAEL01000066_gene1712 2.3e-79 237.0 COG1143@1|root,COG1143@2|Bacteria,1V4RX@1239|Firmicutes,4HHVU@91061|Bacilli,1ZFIA@1386|Bacillus 91061|Bacilli C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoI - 1.6.5.3 ko:K00338 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Fer4 k141_37589_3 935836.JAEL01000066_gene1711 4.5e-36 130.0 COG1005@1|root,COG1005@2|Bacteria,1TQNU@1239|Firmicutes,4HC8R@91061|Bacilli,1ZEMJ@1386|Bacillus 91061|Bacilli C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone nuoH GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 ko:K00337 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - NADHdh k141_29368_1 218284.CCDN010000001_gene1111 3.08e-106 313.0 COG0142@1|root,COG0142@2|Bacteria,1TR0U@1239|Firmicutes,4H9RH@91061|Bacilli,1ZAZ7@1386|Bacillus 91061|Bacilli H Belongs to the FPP GGPP synthase family hepT GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.30,2.5.1.83 ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 - R09245,R09247 RC00279 ko00000,ko00001,ko01000,ko01006 - - - polyprenyl_synt k141_4403_2 1450694.BTS2_2568 7.94e-10 63.5 2DMBQ@1|root,32HI1@2|Bacteria,1VHXM@1239|Firmicutes,4IT0Q@91061|Bacilli,1ZSIF@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - LppX_LprAFG k141_29398_1 1294265.JCM21738_2931 2.99e-112 328.0 COG0760@1|root,COG0760@2|Bacteria,1TX3R@1239|Firmicutes,4HC85@91061|Bacilli,1ZC6P@1386|Bacillus 91061|Bacilli M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins prsA - 5.2.1.8 ko:K01802,ko:K07533 - - - - ko00000,ko01000,ko03110 - - - Rotamase_3,Trigger_C k141_12940_1 218284.CCDN010000005_gene3302 3.36e-106 324.0 COG0475@1|root,COG0569@1|root,COG0475@2|Bacteria,COG0569@2|Bacteria,1TS32@1239|Firmicutes,4H9Q5@91061|Bacilli,1ZBJR@1386|Bacillus 91061|Bacilli P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family yjbQ - - ko:K03455,ko:K03499 - - - - ko00000,ko02000 2.A.37,2.A.38.1,2.A.38.4 - - Na_H_Exchanger,TrkA_C,TrkA_N k141_3216_1 1453501.JELR01000002_gene1112 9.71e-150 444.0 COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,1RNB2@1236|Gammaproteobacteria,464Q3@72275|Alteromonadaceae 1236|Gammaproteobacteria L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrB GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009330,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0032991,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:0140097,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 5.99.1.3 ko:K02470 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim k141_1044_1 1279017.AQYJ01000028_gene2428 2.25e-62 202.0 COG2207@1|root,COG2207@2|Bacteria,1MX23@1224|Proteobacteria,1RRXM@1236|Gammaproteobacteria 1236|Gammaproteobacteria K AraC family transcriptional regulator - - - - - - - - - - - - Arabinose_bd,HTH_18 k141_1044_2 1279017.AQYJ01000028_gene2427 2.39e-88 265.0 COG2824@1|root,COG2824@2|Bacteria,1RGUU@1224|Proteobacteria,1S60W@1236|Gammaproteobacteria,466RW@72275|Alteromonadaceae 1236|Gammaproteobacteria P PhnA domain phnA - - ko:K06193 ko01120,map01120 - - - ko00000 - - - PhnA,PhnA_Zn_Ribbon k141_1044_3 399795.CtesDRAFT_PD1357 2.72e-98 315.0 COG1502@1|root,COG1502@2|Bacteria,1MUDJ@1224|Proteobacteria,2VHSI@28216|Betaproteobacteria,4AAIW@80864|Comamonadaceae 28216|Betaproteobacteria I PFAM Phospholipase D Transphosphatidylase - - - ko:K06132 ko00564,ko01100,map00564,map01100 - R11062 RC00017 ko00000,ko00001,ko01000 - - - PLDc_2 k141_26040_1 218284.CCDN010000001_gene1778 9.89e-28 105.0 2C55I@1|root,32W42@2|Bacteria,1VD5J@1239|Firmicutes,4HMAT@91061|Bacilli,1ZGJA@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_24725_1 218284.CCDN010000001_gene1290 9.57e-121 360.0 COG0143@1|root,COG0143@2|Bacteria,1U7TS@1239|Firmicutes,4HDMP@91061|Bacilli,1ZBPT@1386|Bacillus 91061|Bacilli J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation - - 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1g k141_5762_1 218284.CCDN010000001_gene468 5.13e-38 135.0 COG4586@1|root,COG4586@2|Bacteria,1TP1N@1239|Firmicutes,4H9NR@91061|Bacilli,1ZBGB@1386|Bacillus 91061|Bacilli S transport system, ATPase component - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_5762_2 218284.CCDN010000001_gene467 7.24e-37 131.0 COG0789@1|root,COG0789@2|Bacteria,1TQ78@1239|Firmicutes,4HDKZ@91061|Bacilli,1ZFMU@1386|Bacillus 91061|Bacilli K helix_turn_helix, mercury resistance - - - - - - - - - - - - MerR,MerR_1 k141_22414_1 1453501.JELR01000001_gene2434 8.81e-17 74.3 COG1246@1|root,COG1246@2|Bacteria,1QU0G@1224|Proteobacteria,1TAYS@1236|Gammaproteobacteria,46BU6@72275|Alteromonadaceae 1236|Gammaproteobacteria E Acetyltransferase (GNAT) family - - - - - - - - - - - - Acetyltransf_7 k141_22414_2 1042377.AFPJ01000007_gene1869 1.37e-116 344.0 COG5621@1|root,COG5621@2|Bacteria,1MUVF@1224|Proteobacteria,1RZ65@1236|Gammaproteobacteria,466MJ@72275|Alteromonadaceae 1236|Gammaproteobacteria S secreted hydrolase attH - - - - - - - - - - - CrtC,Lipocalin_9 k141_1936_1 240302.BN982_04037 6.14e-32 114.0 COG0197@1|root,COG0197@2|Bacteria,1V1AY@1239|Firmicutes,4HFPN@91061|Bacilli,3NE7Y@45667|Halobacillus 91061|Bacilli J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs rplP GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - ko:K02878 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L16 k141_37610_1 218284.CCDN010000001_gene276 6.57e-163 466.0 COG1757@1|root,COG1757@2|Bacteria,1TQ3B@1239|Firmicutes,4HA18@91061|Bacilli,1ZBQN@1386|Bacillus 91061|Bacilli C Na H antiporter nhaC_2 - - ko:K03315 - - - - ko00000,ko02000 2.A.35 - - Na_H_antiporter k141_24726_1 1294265.JCM21738_2389 1.06e-111 329.0 COG0668@1|root,COG0668@2|Bacteria,1TR9Z@1239|Firmicutes,4HBDU@91061|Bacilli,1ZBUJ@1386|Bacillus 91061|Bacilli M Mechanosensitive ion channel yhdY - - ko:K16052 - - - - ko00000,ko02000 1.A.23.4 - - MS_channel k141_34216_1 1201293.AKXQ01000004_gene2257 4.7e-150 427.0 COG2116@1|root,COG2116@2|Bacteria,1MU0W@1224|Proteobacteria,1RQ6K@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Formate nitrite fnt - - ko:K06212,ko:K21993 - - - - ko00000,ko02000 1.A.16.1.1,1.A.16.1.3,1.A.16.2 - - Form_Nir_trans k141_31537_1 1453501.JELR01000002_gene1152 3.9e-94 290.0 COG2303@1|root,COG2303@2|Bacteria,1MU3F@1224|Proteobacteria,1RPBQ@1236|Gammaproteobacteria,46842@72275|Alteromonadaceae 1236|Gammaproteobacteria E GMC oxidoreductase - - 1.1.5.9 ko:K19813 ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130 - R00305 RC00066 ko00000,ko00001,ko01000 - - - FAD_binding_2,GIDA,GMC_oxred_C,GMC_oxred_N,NAD_binding_8 k141_31537_2 1453501.JELR01000002_gene1153 1.62e-86 268.0 COG2010@1|root,COG2010@2|Bacteria,1MV6D@1224|Proteobacteria,1RMYF@1236|Gammaproteobacteria,466XG@72275|Alteromonadaceae 1236|Gammaproteobacteria C Cytochrome C oxidase, cbb3-type, subunit III - - - - - - - - - - - - Cytochrom_C,Cytochrome_CBB3 k141_12942_1 218284.CCDN010000008_gene4229 8.62e-130 395.0 COG3383@1|root,COG3383@2|Bacteria,1UHTX@1239|Firmicutes,4IPM7@91061|Bacilli,1ZRCN@1386|Bacillus 91061|Bacilli C formate dehydrogenase, alpha subunit - - 1.17.1.9 ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001,ko01000 - - - Fer2_4,Fer4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3 k141_36392_1 1384049.CD29_15260 1.08e-56 180.0 COG3153@1|root,COG3153@2|Bacteria,1V6YN@1239|Firmicutes,4HKUT@91061|Bacilli 91061|Bacilli S acetyltransferase - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10 k141_20974_2 218284.CCDN010000001_gene1220 1.93e-39 133.0 2FGYP@1|root,348TV@2|Bacteria,1VZPM@1239|Firmicutes,4HYBM@91061|Bacilli,1ZHW2@1386|Bacillus 91061|Bacilli S YokU-like protein, putative antitoxin - - - - - - - - - - - - YokU k141_5763_1 1294265.JCM21738_3582 1.97e-50 169.0 2ECNW@1|root,336KN@2|Bacteria,1VDVP@1239|Firmicutes,4HKM3@91061|Bacilli,1ZKRA@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_37611_1 1223523.H340_10745 2.32e-18 83.2 28HIR@1|root,2Z7U4@2|Bacteria,2GN2S@201174|Actinobacteria 201174|Actinobacteria S succinate dehydrogenase sdhC - - ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002 - - - Sdh_cyt k141_37611_2 309807.SRU_1571 3.83e-51 171.0 COG0039@1|root,COG0039@2|Bacteria,4NEJ7@976|Bacteroidetes,1FJ1J@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes C Catalyzes the reversible oxidation of malate to oxaloacetate mdh - 1.1.1.37 ko:K00024 ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740 R00342,R07136 RC00031 ko00000,ko00001,ko00002,ko01000 - - - Ldh_1_C,Ldh_1_N k141_1045_4 218284.CCDN010000008_gene4159 1.47e-47 155.0 COG0494@1|root,COG0494@2|Bacteria,1VD7F@1239|Firmicutes,4HKEZ@91061|Bacilli,1ZQSR@1386|Bacillus 91061|Bacilli L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - - NUDIX k141_3218_1 1121378.KB899745_gene3736 5.45e-56 192.0 COG3039@1|root,COG3039@2|Bacteria 2|Bacteria L Transposase - - - - - - - - - - - - DDE_Tnp_1_6,DUF772 k141_7011_1 218284.CCDN010000001_gene180 1.06e-90 271.0 COG0730@1|root,COG0730@2|Bacteria,1TQBK@1239|Firmicutes,4HBCW@91061|Bacilli,1ZCK1@1386|Bacillus 91061|Bacilli S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE k141_36393_1 218284.CCDN010000001_gene758 8.5e-56 180.0 COG1806@1|root,COG1806@2|Bacteria,1TPG0@1239|Firmicutes,4HB0Q@91061|Bacilli,1ZBIT@1386|Bacillus 91061|Bacilli S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation yqfL - 2.7.11.33,2.7.4.28 ko:K09773 - - - - ko00000,ko01000 - - - Kinase-PPPase k141_36393_2 218284.CCDN010000001_gene757 3.76e-53 171.0 COG0517@1|root,COG0517@2|Bacteria,1TRZD@1239|Firmicutes,4HC4C@91061|Bacilli,1ZB0P@1386|Bacillus 91061|Bacilli K CBS domain ccpN GO:0006355,GO:0007154,GO:0007584,GO:0008150,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0042221,GO:0045013,GO:0045892,GO:0045934,GO:0045990,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0061984,GO:0061985,GO:0065007,GO:0070887,GO:0071496,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - - - - - - - - - - CBS,HTH_11 k141_24730_1 1294265.JCM21738_2830 7.57e-116 338.0 2DB9X@1|root,2Z7ZS@2|Bacteria,1VS9F@1239|Firmicutes,4HTUJ@91061|Bacilli,1ZC1U@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3445) - - 1.14.13.238 ko:K22342 - - - - ko00000,ko01000 - - - DUF3445 k141_1046_1 1273538.G159_09220 3.97e-126 367.0 COG2064@1|root,COG2064@2|Bacteria,1URSD@1239|Firmicutes,4HAR7@91061|Bacilli,26G5J@186818|Planococcaceae 91061|Bacilli NU Type II secretion system (T2SS), protein F - - - ko:K12511 - - - - ko00000,ko02044 - - - T2SSF k141_31538_1 1145276.T479_22165 1.38e-38 135.0 COG2318@1|root,COG2318@2|Bacteria,1VAGC@1239|Firmicutes,4HMA9@91061|Bacilli,3IYDM@400634|Lysinibacillus 91061|Bacilli S Mycothiol maleylpyruvate isomerase N-terminal domain - - - - - - - - - - - - DinB_2 k141_31538_2 665959.HMPREF1013_04908 5.32e-10 60.1 COG0069@1|root,COG0069@2|Bacteria,1TSHA@1239|Firmicutes,4HA97@91061|Bacilli,1ZCQH@1386|Bacillus 91061|Bacilli E Belongs to the glutamate synthase family yerD GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.7.1 ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 - R00021,R10086 RC00006,RC00010 ko00000,ko00001,ko01000 - - - Glu_synthase k141_30387_2 319795.Dgeo_2502 1.01e-35 135.0 COG2244@1|root,COG2244@2|Bacteria,1WKII@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S polysaccharide biosynthetic process - - - - - - - - - - - - - k141_10466_1 1116375.VEJY3_22071 3.87e-38 130.0 2B6R3@1|root,31ZPX@2|Bacteria,1QKIS@1224|Proteobacteria,1TIP2@1236|Gammaproteobacteria,1XZEB@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_10466_2 1116375.VEJY3_22076 1.1e-56 177.0 2AWB1@1|root,31N6Q@2|Bacteria,1QJXY@1224|Proteobacteria,1TI04@1236|Gammaproteobacteria,1XY27@135623|Vibrionales 135623|Vibrionales K transcriptional regulator with C-terminal CBS domains - - - - - - - - - - - - HTH_3,HTH_31 k141_10466_3 1116375.VEJY3_22081 2.87e-69 220.0 2E3X2@1|root,31URP@2|Bacteria,1QJN8@1224|Proteobacteria,1THNY@1236|Gammaproteobacteria,1XWZ7@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_10466_4 1116375.VEJY3_22396 1.92e-84 248.0 COG1403@1|root,COG1403@2|Bacteria,1RGZQ@1224|Proteobacteria,1S5V4@1236|Gammaproteobacteria,1XXGJ@135623|Vibrionales 135623|Vibrionales V zinc finger yajD - - - - - - - - - - - HNH k141_35490_1 1279017.AQYJ01000027_gene1745 6.74e-39 145.0 COG1629@1|root,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria,465TV@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_1047_1 42565.FP66_11030 1.04e-88 269.0 COG1473@1|root,COG1473@2|Bacteria,1MUIV@1224|Proteobacteria,1RQAM@1236|Gammaproteobacteria,1XHM5@135619|Oceanospirillales 135619|Oceanospirillales S peptidase M20 - - - - - - - - - - - - M20_dimer,Peptidase_M20 k141_24731_1 997346.HMPREF9374_0754 2.99e-73 226.0 COG1878@1|root,COG1878@2|Bacteria,1VHB1@1239|Firmicutes,4HTRQ@91061|Bacilli,27BR0@186824|Thermoactinomycetaceae 91061|Bacilli S Putative cyclase - - - - - - - - - - - - Cyclase k141_22419_1 218284.CCDN010000007_gene3934 1.3e-78 234.0 COG3773@1|root,COG3773@2|Bacteria,1V3QK@1239|Firmicutes,4HH00@91061|Bacilli,1ZGB9@1386|Bacillus 91061|Bacilli M Cell wall cwlJ - 3.5.1.28 ko:K01449 - - R04112 RC00064,RC00141 ko00000,ko01000 - - - Hydrolase_2 k141_22419_2 218284.CCDN010000007_gene3933 2.76e-20 85.1 2CWP1@1|root,32T03@2|Bacteria,1VAD2@1239|Firmicutes,4HKGQ@91061|Bacilli,1ZH2J@1386|Bacillus 91061|Bacilli S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA gerQ GO:0005575,GO:0005618,GO:0005623,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0018149,GO:0018153,GO:0018193,GO:0018199,GO:0018205,GO:0018262,GO:0019538,GO:0030312,GO:0031160,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0071704,GO:0071944,GO:1901564 - ko:K06305 - - - - ko00000 - - - Spore_GerQ k141_28025_1 42565.FP66_00250 3.28e-140 407.0 COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,1RN88@1236|Gammaproteobacteria,1XH8C@135619|Oceanospirillales 135619|Oceanospirillales M Belongs to the MurCDEF family murC - 6.3.2.8 ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M k141_10467_1 218284.CCDN010000008_gene4175 4.54e-48 162.0 COG2141@1|root,COG2141@2|Bacteria,1TPRS@1239|Firmicutes,4H9R2@91061|Bacilli,1ZB1E@1386|Bacillus 91061|Bacilli C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases ywcH GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - - - - - - - - - - Bac_luciferase k141_10467_2 1385514.N782_11315 3.36e-23 97.8 COG4412@1|root,COG4412@2|Bacteria,1TQYP@1239|Firmicutes,4HD82@91061|Bacilli,2YA1P@289201|Pontibacillus 91061|Bacilli S protease - - - ko:K09607 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M6 k141_30388_1 1294265.JCM21738_5247 5.77e-109 328.0 COG1293@1|root,COG1293@2|Bacteria,1TQ8A@1239|Firmicutes,4H9UF@91061|Bacilli,1ZBGD@1386|Bacillus 91061|Bacilli K RNA-binding protein homologous to eukaryotic snRNP FbpA - - - - - - - - - - - DUF814,FbpA k141_5764_1 1042377.AFPJ01000007_gene1893 8.96e-195 554.0 COG4425@1|root,COG4425@2|Bacteria,1MXSU@1224|Proteobacteria,1RYFH@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Alpha/beta-hydrolase family N-terminus - - - - - - - - - - - - Abhydrolase_9,Abhydrolase_9_N k141_24732_2 1405.DJ92_797 1.89e-55 182.0 COG0454@1|root,COG1357@1|root,COG0456@2|Bacteria,COG1357@2|Bacteria,1V5QZ@1239|Firmicutes,4I2JE@91061|Bacilli,1ZDWX@1386|Bacillus 91061|Bacilli K Pentapeptide repeats (9 copies) - - - - - - - - - - - - Acetyltransf_7,Pentapeptide,Pentapeptide_4 k141_22440_1 1453501.JELR01000001_gene2656 2.23e-67 208.0 COG3431@1|root,COG3431@2|Bacteria,1RJWK@1224|Proteobacteria,1S2UP@1236|Gammaproteobacteria,467I3@72275|Alteromonadaceae 1236|Gammaproteobacteria S Phosphate-starvation-inducible E - - - - - - - - - - - - PsiE k141_5781_1 218284.CCDN010000005_gene3347 4.08e-165 471.0 COG1972@1|root,COG1972@2|Bacteria,1TRSK@1239|Firmicutes,4HA8N@91061|Bacilli,1ZAW2@1386|Bacillus 91061|Bacilli F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family yutK GO:0003674,GO:0005215,GO:0005337,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0015858,GO:0015931,GO:0015932,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:1901264,GO:1901505,GO:1901642 - ko:K03317 - - - - ko00000 2.A.41 - iYO844.BSU32180 Gate,Nucleos_tra2_C,Nucleos_tra2_N k141_32941_1 1279017.AQYJ01000028_gene2451 1.77e-64 219.0 COG3468@1|root,COG3468@2|Bacteria,1R8WV@1224|Proteobacteria 1224|Proteobacteria MU outer membrane autotransporter barrel domain - - - ko:K19231 - - - - ko00000,ko02000 1.B.12 - - Autotransporter,Pertactin k141_32941_2 314278.NB231_15358 3.85e-195 553.0 COG2270@1|root,COG2270@2|Bacteria,1MWXB@1224|Proteobacteria,1S03J@1236|Gammaproteobacteria,1WYH5@135613|Chromatiales 135613|Chromatiales S Major facilitator superfamily - - - ko:K06902 ko04138,map04138 - - - ko00000,ko00001,ko02000,ko04131 2.A.1.24,9.A.15.1 - - ATG22 k141_32941_3 225937.HP15_3155 3.11e-117 338.0 COG4341@1|root,COG4341@2|Bacteria,1QHQD@1224|Proteobacteria,1S2ZI@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phosphohydrolase - - - - - - - - - - - - HD k141_28048_1 1453501.JELR01000001_gene1914 1.05e-09 58.2 COG0613@1|root,COG0613@2|Bacteria,1MWIH@1224|Proteobacteria,1RNCG@1236|Gammaproteobacteria,466MQ@72275|Alteromonadaceae 1236|Gammaproteobacteria S metal-dependent phosphoesterases (PHP family) trpH GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004532,GO:0004534,GO:0004536,GO:0004540,GO:0005488,GO:0006139,GO:0006259,GO:0006521,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008252,GO:0008409,GO:0009987,GO:0010565,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016796,GO:0016895,GO:0016896,GO:0019222,GO:0030145,GO:0031323,GO:0033238,GO:0034641,GO:0035312,GO:0042578,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090305,GO:0090357,GO:0090501,GO:0090503,GO:0140097,GO:0140098,GO:1901360 3.1.3.97 ko:K07053 - - R00188,R11188 RC00078 ko00000,ko01000 - - - PHP k141_35515_2 218284.CCDN010000010_gene4396 1.56e-125 357.0 COG3880@1|root,COG3880@2|Bacteria,1V6YM@1239|Firmicutes,4HH4R@91061|Bacilli,1ZG9T@1386|Bacillus 91061|Bacilli S protein with conserved CXXC pairs mcsA GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 - ko:K19411 - - - - ko00000 - - - UVR k141_29422_1 218284.CCDN010000001_gene751 4.38e-44 147.0 COG0818@1|root,COG0818@2|Bacteria,1VEGR@1239|Firmicutes,4HNKN@91061|Bacilli,1ZHW0@1386|Bacillus 91061|Bacilli M Diacylglycerol kinase dgkA - 2.7.1.107,2.7.1.66 ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 - R02240,R05626 RC00002,RC00017 ko00000,ko00001,ko01000 - - iSB619.SA_RS07900 DAGK_prokar k141_22441_1 1340493.JNIF01000003_gene3504 9.48e-53 178.0 COG0382@1|root,COG0382@2|Bacteria,3Y3CW@57723|Acidobacteria 57723|Acidobacteria H PFAM UbiA prenyltransferase - - 2.5.1.39 ko:K03179 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R05000,R05615 RC00209,RC02895 ko00000,ko00001,ko00002,ko01000,ko01006 - - - UbiA k141_20019_1 55601.VANGNB10_cII0338c 1.58e-203 576.0 28JKN@1|root,2Z9DE@2|Bacteria,1N4VH@1224|Proteobacteria,1SA4H@1236|Gammaproteobacteria 1236|Gammaproteobacteria S MvaI/BcnI restriction endonuclease family - - - - - - - - - - - - MvaI_BcnI k141_11817_1 1294265.JCM21738_1871 3.79e-121 354.0 COG2181@1|root,COG2181@2|Bacteria,1V067@1239|Firmicutes,4HCYT@91061|Bacilli,1ZDYD@1386|Bacillus 91061|Bacilli C nitrate reductase activity - - - - - - - - - - - - - k141_3241_2 218284.CCDN010000001_gene994 1.27e-124 358.0 COG0765@1|root,COG0765@2|Bacteria,1TPM3@1239|Firmicutes,4HAS2@91061|Bacilli,1ZBUZ@1386|Bacillus 91061|Bacilli E COG0765 ABC-type amino acid transport system, permease component artQ GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015318,GO:0015711,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1903825,GO:1905039 - ko:K02029 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 k141_32942_1 316275.VSAL_II0266 2.53e-75 235.0 COG0451@1|root,COG0451@2|Bacteria,1QT6B@1224|Proteobacteria,1RWTE@1236|Gammaproteobacteria,1XUR5@135623|Vibrionales 135623|Vibrionales M Male sterility protein - - - - - - - - - - - - Epimerase k141_33210_1 1385511.N783_15860 1.15e-57 194.0 COG3356@1|root,COG3356@2|Bacteria,1V42W@1239|Firmicutes,4HK1K@91061|Bacilli 91061|Bacilli S Neutral/alkaline non-lysosomal ceramidase, N-terminal - - - - - - - - - - - - Ceramidase_alk k141_2278_1 218284.CCDN010000001_gene1190 2.28e-84 254.0 COG1418@1|root,COG1418@2|Bacteria,1V7IZ@1239|Firmicutes,4HIVB@91061|Bacilli,1ZB0E@1386|Bacillus 91061|Bacilli S phosphohydrolase ypgQ - - ko:K06950 - - - - ko00000 - - - HD k141_16597_1 443255.SCLAV_p1379 6.94e-05 52.0 COG3420@1|root,COG3420@2|Bacteria,2GNYS@201174|Actinobacteria 201174|Actinobacteria P Periplasmic copper-binding protein (NosD) - - - - - - - - - - - - Beta_helix k141_17789_1 1449063.JMLS01000021_gene860 1.6e-30 116.0 COG1041@1|root,COG1041@2|Bacteria,1TRH9@1239|Firmicutes,4HCHR@91061|Bacilli,26RR5@186822|Paenibacillaceae 91061|Bacilli L RNA methyltransferase rumA - - - - - - - - - - - UPF0020 k141_17789_2 218284.CCDN010000001_gene1602 2.98e-95 283.0 COG0515@1|root,COG0515@2|Bacteria,1UTWM@1239|Firmicutes,4H9YQ@91061|Bacilli,1ZR6X@1386|Bacillus 91061|Bacilli KLT serine threonine protein kinase - - - - - - - - - - - - - k141_21290_1 1279017.AQYJ01000028_gene2415 6.77e-164 468.0 COG0265@1|root,COG0265@2|Bacteria,1NXB0@1224|Proteobacteria,1RRAD@1236|Gammaproteobacteria,465AC@72275|Alteromonadaceae 1236|Gammaproteobacteria O Trypsin-like peptidase domain - - - - - - - - - - - - Trypsin_2 k141_15288_2 218284.CCDN010000001_gene630 1.13e-44 152.0 COG0739@1|root,COG0739@2|Bacteria,1TSQI@1239|Firmicutes,4HFC8@91061|Bacilli,1ZFJN@1386|Bacillus 91061|Bacilli M COG0739 Membrane proteins related to metalloendopeptidases spoIVFA - - ko:K06401 - - - - ko00000 - - - Peptidase_M23 k141_2279_1 1294265.JCM21738_4675 3.37e-137 397.0 COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,4HA3G@91061|Bacilli,1ZAVY@1386|Bacillus 91061|Bacilli T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,PAS_4,PAS_9 k141_16598_1 218284.CCDN010000001_gene723 4.34e-82 269.0 COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,4H9M4@91061|Bacilli,1ZBWR@1386|Bacillus 91061|Bacilli S Competence protein ComEC comEC - - ko:K02238 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - Competence,DUF4131,Lactamase_B k141_30598_1 406124.ACPC01000045_gene4058 3.7e-100 301.0 COG2059@1|root,COG2059@2|Bacteria,1TSKA@1239|Firmicutes,4HBB1@91061|Bacilli,1ZDC5@1386|Bacillus 91061|Bacilli P chromate transporter, chromate ion transporter chrA - - ko:K07240 - - - - ko00000,ko02000 2.A.51.1 - - Chromate_transp k141_30598_2 218284.CCDN010000001_gene1724 5.34e-16 71.6 COG1695@1|root,COG1695@2|Bacteria,1V8K6@1239|Firmicutes,4HJY6@91061|Bacilli,1ZHGP@1386|Bacillus 91061|Bacilli K Transcriptional regulator PadR-like family - - - - - - - - - - - - PadR k141_37908_1 1279017.AQYJ01000027_gene1696 1.5e-220 623.0 COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,1RMT7@1236|Gammaproteobacteria,4640X@72275|Alteromonadaceae 1236|Gammaproteobacteria S Bacterial protein of unknown function (DUF885) - - - - - - - - - - - - DUF885 k141_36597_1 866895.HBHAL_4209 2.28e-56 198.0 COG2273@1|root,COG2273@2|Bacteria,1TR5U@1239|Firmicutes,4HB9D@91061|Bacilli 91061|Bacilli G PFAM glycoside hydrolase family 16 - - - - - - - - - - - - CBM_4_9,Glyco_hydro_16,SLH k141_17790_1 1279017.AQYJ01000021_gene2922 3.3e-41 148.0 COG0642@1|root,COG2205@2|Bacteria,1QTVU@1224|Proteobacteria,1RPFY@1236|Gammaproteobacteria,4653U@72275|Alteromonadaceae 1236|Gammaproteobacteria T Signal transduction histidine kinase phoQ GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010350,GO:0016020,GO:0016021,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0031224,GO:0031226,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0035556,GO:0036211,GO:0042578,GO:0042594,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046777,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071496,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.7.13.3 ko:K07637 ko01503,ko02020,map01503,map02020 M00444,M00709,M00721,M00723,M00724,M00744 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 - - - HATPase_c,HisKA,PhoQ_Sensor k141_17790_2 1245471.PCA10_29790 4.88e-63 212.0 COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,1RPHJ@1236|Gammaproteobacteria,1YE66@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria I Acyl-CoA dehydrogenase N terminal bcd - 1.3.8.1 ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 - R01175,R01178,R02661,R03172,R04751 RC00052,RC00068,RC00076,RC00120,RC00148 ko00000,ko00001,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N k141_33212_1 1340434.AXVA01000008_gene3479 7.03e-16 79.0 2CDJQ@1|root,2Z7JX@2|Bacteria,1TR73@1239|Firmicutes,4HAT1@91061|Bacilli,1ZRA6@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_15289_1 1169144.KB910956_gene4101 7.86e-21 91.7 COG0115@1|root,COG0115@2|Bacteria,1TSIP@1239|Firmicutes,4HC7K@91061|Bacilli,1ZCRC@1386|Bacillus 91061|Bacilli EH 4-amino-4-deoxychorismate lyase pabC - 4.1.3.38 ko:K02619 ko00790,map00790 - R05553 RC01843,RC02148 ko00000,ko00001,ko01000 - - - Aminotran_4 k141_8110_1 1227360.C176_02528 1.92e-18 84.0 COG0406@1|root,COG0406@2|Bacteria,1V6ES@1239|Firmicutes,4HGZI@91061|Bacilli,26FNE@186818|Planococcaceae 91061|Bacilli G Belongs to the phosphoglycerate mutase family yhfR - 5.4.2.12 ko:K15634,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000 - - - His_Phos_1 k141_8110_2 218284.CCDN010000001_gene1322 3.64e-55 175.0 COG3011@1|root,COG3011@2|Bacteria,1V7DJ@1239|Firmicutes,4HIUD@91061|Bacilli,1ZH0A@1386|Bacillus 91061|Bacilli S protein conserved in bacteria yuxK - - - - - - - - - - - DUF393 k141_8110_3 218284.CCDN010000001_gene1323 1.18e-67 207.0 COG0432@1|root,COG0432@2|Bacteria,1V6J7@1239|Firmicutes,4HI2R@91061|Bacilli,1ZGBA@1386|Bacillus 91061|Bacilli S Uncharacterised protein family UPF0047 yugU - - - - - - - - - - - UPF0047 k141_17791_1 218284.CCDN010000002_gene2121 2.83e-135 396.0 COG0119@1|root,COG0119@2|Bacteria,1TP4Y@1239|Firmicutes,4HA6E@91061|Bacilli,1ZC5T@1386|Bacillus 91061|Bacilli E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) leuA - 2.3.3.13 ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 M00432 R01213 RC00004,RC00470,RC02754 br01601,ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS10690,iYO844.BSU28280 HMGL-like,LeuA_dimer k141_37910_1 1042377.AFPJ01000025_gene587 4.96e-59 186.0 COG1546@1|root,COG1546@2|Bacteria,1RH2Y@1224|Proteobacteria,1S5WH@1236|Gammaproteobacteria,4677Y@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the CinA family ygaD GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016811,GO:0019159 3.5.1.42 ko:K03743 ko00760,map00760 - R02322 RC00100 ko00000,ko00001,ko01000 - - - CinA k141_36598_1 218284.CCDN010000001_gene1105 1.44e-192 544.0 COG0699@1|root,COG0699@2|Bacteria,1TPPG@1239|Firmicutes,4HBH1@91061|Bacilli,1ZBNH@1386|Bacillus 91061|Bacilli S ATPase. Has a role at an early stage in the morphogenesis of the spore coat spoIVA GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009653,GO:0009847,GO:0009987,GO:0010927,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022607,GO:0030154,GO:0030203,GO:0030312,GO:0030435,GO:0030554,GO:0031160,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0032989,GO:0034622,GO:0035639,GO:0036094,GO:0042244,GO:0042546,GO:0042601,GO:0042763,GO:0043167,GO:0043168,GO:0043170,GO:0043591,GO:0043595,GO:0043933,GO:0043934,GO:0044085,GO:0044426,GO:0044462,GO:0044464,GO:0045229,GO:0048646,GO:0048856,GO:0048869,GO:0051258,GO:0051259,GO:0065003,GO:0070499,GO:0070590,GO:0070726,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 - ko:K06398 - - - - ko00000 - - - Spore_IV_A k141_2281_1 1270196.JCKI01000001_gene3878 1.1e-18 86.7 COG2107@1|root,COG2107@2|Bacteria,4NFAN@976|Bacteroidetes,1INXU@117747|Sphingobacteriia 976|Bacteroidetes S Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) mqnD - - ko:K11785 ko00130,ko01110,map00130,map01110 - R08589 RC02330 ko00000,ko00001,ko01000 - - - VitK2_biosynth k141_8111_1 1453501.JELR01000001_gene1868 5.11e-85 261.0 COG0707@1|root,COG0707@2|Bacteria,1MWQP@1224|Proteobacteria,1T31H@1236|Gammaproteobacteria,46D2Z@72275|Alteromonadaceae 1236|Gammaproteobacteria M Glycosyl transferase family 1 - - - - - - - - - - - - Glyco_trans_1_3 k141_17793_1 218284.CCDN010000003_gene3001 4.14e-128 369.0 COG0515@1|root,COG0515@2|Bacteria,1TSNS@1239|Firmicutes,4HBDI@91061|Bacilli,1ZBVA@1386|Bacillus 91061|Bacilli KLT serine threonine protein kinase yabT - 2.7.11.1 ko:K08884 - - - - ko00000,ko01000,ko01001 - - - Pkinase k141_10696_1 1279017.AQYJ01000027_gene1781 5.03e-60 202.0 COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,1RNR3@1236|Gammaproteobacteria,464RV@72275|Alteromonadaceae 1236|Gammaproteobacteria J Glycyl-tRNA synthetase beta subunit glyS GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.14 ko:K01879 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iAPECO1_1312.APECO1_2891,iE2348C_1286.E2348C_3810,iECABU_c1320.ECABU_c40010,iECED1_1282.ECED1_4242,iECH74115_1262.ECH74115_4934,iECNA114_1301.ECNA114_3710,iECOK1_1307.ECOK1_4005,iECP_1309.ECP_3661,iECS88_1305.ECS88_3976,iECSF_1327.ECSF_3393,iECSP_1301.ECSP_4554,iECs_1301.ECs4442,iG2583_1286.G2583_4300,iUMN146_1321.UM146_17960,iUTI89_1310.UTI89_C4099,ic_1306.c4378 DALR_1,tRNA_synt_2f k141_10696_2 1279017.AQYJ01000027_gene1780 3.1e-226 624.0 COG0752@1|root,COG0752@2|Bacteria,1MVCJ@1224|Proteobacteria,1RMYI@1236|Gammaproteobacteria,4640E@72275|Alteromonadaceae 1236|Gammaproteobacteria J glycyl-tRNA synthetase alpha subunit glyQ GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 6.1.1.14 ko:K01878 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iAF1260.b3560,iJO1366.b3560,iPC815.YPO4072,iY75_1357.Y75_RS19360 tRNA-synt_2e k141_10696_3 1279017.AQYJ01000027_gene1779 4.9e-155 441.0 COG1560@1|root,COG1560@2|Bacteria,1Q41N@1224|Proteobacteria,1RRRE@1236|Gammaproteobacteria,466K6@72275|Alteromonadaceae 1236|Gammaproteobacteria M Bacterial lipid A biosynthesis acyltransferase htrB - 2.3.1.241 ko:K02517 ko00540,ko01100,map00540,map01100 M00060 R05146 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Lip_A_acyltrans k141_10696_4 1279019.ARQK01000044_gene2369 9.4e-106 325.0 COG1972@1|root,COG1972@2|Bacteria,1MXXX@1224|Proteobacteria,1RMBX@1236|Gammaproteobacteria,1WXBG@135613|Chromatiales 135613|Chromatiales F PFAM Na dependent nucleoside transporter - - - ko:K03317 - - - - ko00000 2.A.41 - - Gate,Nucleos_tra2_C,Nucleos_tra2_N k141_10696_7 1279017.AQYJ01000027_gene1773 4.92e-303 830.0 COG0569@1|root,COG0569@2|Bacteria,1MW8R@1224|Proteobacteria,1RNVQ@1236|Gammaproteobacteria,464GU@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0569 K transport systems, NAD-binding component trkA GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0015075,GO:0015672,GO:0016020,GO:0022857,GO:0030001,GO:0034220,GO:0051179,GO:0051234,GO:0055085,GO:0098655 - ko:K03499 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - iE2348C_1286.E2348C_3552 TrkA_C,TrkA_N k141_10696_8 1279017.AQYJ01000027_gene1772 1.76e-221 621.0 COG0144@1|root,COG0144@2|Bacteria,1MWPE@1224|Proteobacteria,1RN8X@1236|Gammaproteobacteria,465KP@72275|Alteromonadaceae 1236|Gammaproteobacteria J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA sun GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 ko:K03500 - - - - ko00000,ko01000,ko03009 - - - Methyltr_RsmB-F,Methyltr_RsmF_N,NusB k141_10696_11 1453501.JELR01000002_gene1096 8.39e-193 542.0 COG1652@1|root,COG1652@2|Bacteria,1MUBV@1224|Proteobacteria,1RPMB@1236|Gammaproteobacteria,463ZS@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein containing LysM domain lysM - - - - - - - - - - - LysM k141_10696_12 1042377.AFPJ01000012_gene1362 9.84e-158 456.0 COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,1RPJE@1236|Gammaproteobacteria,465H4@72275|Alteromonadaceae 1236|Gammaproteobacteria LU Rossmann fold nucleotide-binding protein involved in DNA uptake smf - - ko:K04096 - - - - ko00000 - - - DNA_processg_A k141_10696_13 1279017.AQYJ01000027_gene1766 1.06e-88 263.0 COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,1S3VN@1236|Gammaproteobacteria,466US@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) purE - 5.4.99.18 ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07405 RC01947 ko00000,ko00001,ko00002,ko01000 - - - AIRC k141_10696_14 351348.Maqu_0046 6.26e-56 182.0 COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,1S610@1236|Gammaproteobacteria,4677N@72275|Alteromonadaceae 1236|Gammaproteobacteria J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-) CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate tsaC GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061710,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87 ko:K07566 - - R10463 RC00745 ko00000,ko01000,ko03009,ko03016 - - - Sua5_yciO_yrdC k141_10696_15 1484158.PSNIH1_01035 2.09e-172 486.0 COG0408@1|root,COG0408@2|Bacteria,1MWMF@1224|Proteobacteria,1RMM8@1236|Gammaproteobacteria,3VZ9Q@53335|Pantoea 1236|Gammaproteobacteria H Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX hemF GO:0003674,GO:0003824,GO:0004109,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0016634,GO:0018130,GO:0019438,GO:0030145,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046906,GO:0046914,GO:0046983,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.3.3.3 ko:K00228 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03220 RC00884 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b2436,iBWG_1329.BWG_2198,iECDH10B_1368.ECDH10B_2601,iECDH1ME8569_1439.ECDH1ME8569_2370,iETEC_1333.ETEC_2549,iEcDH1_1363.EcDH1_1225,iEcHS_1320.EcHS_A2573,iEcolC_1368.EcolC_1243,iJO1366.b2436,iJR904.b2436,iY75_1357.Y75_RS12760 Coprogen_oxidas k141_10696_17 1042377.AFPJ01000012_gene1366 1.8e-114 337.0 COG0169@1|root,COG0169@2|Bacteria,1MVH4@1224|Proteobacteria,1RPB7@1236|Gammaproteobacteria,4647Q@72275|Alteromonadaceae 1236|Gammaproteobacteria E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) aroE GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_3165,iECOK1_1307.ECOK1_3701,iECS88_1305.ECS88_3669,iECUMN_1333.ECUMN_3755,iSBO_1134.SBO_3275,iUMN146_1321.UM146_16315,iUTI89_1310.UTI89_C3726 Shikimate_DH,Shikimate_dh_N k141_10696_18 1453501.JELR01000002_gene1087 3.76e-55 175.0 2C46F@1|root,32SRD@2|Bacteria,1N540@1224|Proteobacteria,1S8P6@1236|Gammaproteobacteria,46CCG@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_21293_1 1121923.GPUN_2225 1.03e-161 486.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Receptor - - - - - - - - - - - - Plug,TonB_dep_Rec k141_4673_1 1120983.KB894572_gene2984 3.71e-10 65.5 COG0110@1|root,COG0110@2|Bacteria,1MUCJ@1224|Proteobacteria,2TU30@28211|Alphaproteobacteria 28211|Alphaproteobacteria S COG0110 Acetyltransferase (isoleucine patch superfamily - - 2.3.1.28 ko:K00638,ko:K18234 - - - - br01600,ko00000,ko01000,ko01504 - - - Hexapep k141_4673_2 435591.BDI_1466 2.06e-18 94.7 COG2244@1|root,COG2244@2|Bacteria,4NFF1@976|Bacteroidetes,2FTXJ@200643|Bacteroidia,22YEA@171551|Porphyromonadaceae 976|Bacteroidetes S Polysaccharide biosynthesis protein - - - ko:K03328 - - - - ko00000 2.A.66.2 - - Polysacc_synt,Polysacc_synt_C k141_4673_4 1051646.VITU9109_13017 1.15e-145 417.0 COG1091@1|root,COG1091@2|Bacteria,1MUXM@1224|Proteobacteria,1RSNR@1236|Gammaproteobacteria,1XV68@135623|Vibrionales 135623|Vibrionales M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose rmlD - 1.1.1.133 ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777 RC00182 ko00000,ko00001,ko00002,ko01000 - - - RmlD_sub_bind k141_4673_6 223926.28805204 1.72e-246 678.0 COG1088@1|root,COG1088@2|Bacteria,1MU5E@1224|Proteobacteria,1RP7G@1236|Gammaproteobacteria,1XUQ1@135623|Vibrionales 135623|Vibrionales M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily rffG - 4.2.1.46 ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 M00793 R06513 RC00402 ko00000,ko00001,ko00002,ko01000 - - - GDP_Man_Dehyd k141_16600_1 1042377.AFPJ01000014_gene1634 1.37e-175 494.0 COG2755@1|root,COG2755@2|Bacteria,1NAAJ@1224|Proteobacteria 1224|Proteobacteria E GDSL-like Lipase/Acylhydrolase - - - - - - - - - - - - Lipase_GDSL,Lipase_GDSL_2 k141_16600_2 1279017.AQYJ01000026_gene401 1.95e-31 119.0 COG1651@1|root,COG1651@2|Bacteria 2|Bacteria O Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - 5.3.4.1 ko:K03981 - - - - ko00000,ko01000,ko02044,ko03110 3.A.7.11.1 - - DSBA,Thioredoxin_2,Thioredoxin_4 k141_34464_2 1453501.JELR01000001_gene2952 2.23e-89 270.0 COG4067@1|root,COG4067@2|Bacteria,1N7Y2@1224|Proteobacteria,1S91D@1236|Gammaproteobacteria,46CZQ@72275|Alteromonadaceae 1236|Gammaproteobacteria O Putative ATP-dependant zinc protease - - - - - - - - - - - - Zn_protease k141_34464_3 391615.ABSJ01000034_gene1041 9.41e-25 97.1 COG3098@1|root,COG3098@2|Bacteria,1N7AG@1224|Proteobacteria,1SCXJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria yqcC GO:0008150,GO:0009987,GO:0042710,GO:0044010,GO:0044764,GO:0051704 5.1.3.13 ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R06514 RC01531 ko00000,ko00001,ko00002,ko01000 - - - DUF446 k141_17794_1 218284.CCDN010000005_gene3385 2.33e-112 332.0 COG0520@1|root,COG0520@2|Bacteria,1TQ1W@1239|Firmicutes,4HA6Z@91061|Bacilli,1ZB79@1386|Bacillus 91061|Bacilli E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine sufS - 2.8.1.7,4.4.1.16 ko:K11717 ko00450,ko01100,map00450,map01100 - R03599,R11528 RC00961,RC01789,RC02313 ko00000,ko00001,ko01000 - - - Aminotran_5 k141_30600_1 1071073.KI530546_gene2773 2.06e-210 588.0 COG1404@1|root,COG1404@2|Bacteria,1TQ2M@1239|Firmicutes,4HB7D@91061|Bacilli,1ZAZE@1386|Bacillus 91061|Bacilli O Belongs to the peptidase S8 family - - 3.4.21.66 ko:K08651 - - - - ko00000,ko01000,ko01002,ko03110 - - - Peptidase_S8 k141_4736_2 218284.CCDN010000001_gene621 3.16e-45 154.0 2BA87@1|root,323NA@2|Bacteria,1V54Z@1239|Firmicutes,4HGZH@91061|Bacilli,1ZIG0@1386|Bacillus 91061|Bacilli - - - - - ko:K02664 - - - - ko00000,ko02035,ko02044 - - - LysM,PilO k141_15312_1 1029824.AFID01000002_gene1580 3.98e-33 125.0 COG0709@1|root,COG0709@2|Bacteria,2GNP4@201174|Actinobacteria,1W8R0@1268|Micrococcaceae 201174|Actinobacteria E Synthesizes selenophosphate from selenide and ATP selD - 2.7.9.3 ko:K01008 ko00450,ko01100,map00450,map01100 - R03595 RC00002,RC02878 ko00000,ko00001,ko01000,ko03016 - - - AIRS,AIRS_C k141_16632_1 42565.FP66_13370 3.27e-104 301.0 COG0782@1|root,COG0782@2|Bacteria,1RCXW@1224|Proteobacteria,1S3UP@1236|Gammaproteobacteria,1XJHQ@135619|Oceanospirillales 135619|Oceanospirillales K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides greA - - ko:K03624 - - - - ko00000,ko03021 - - - GreA_GreB,GreA_GreB_N k141_16632_2 42565.FP66_13365 1.89e-27 110.0 COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,1RPIU@1236|Gammaproteobacteria,1XHKH@135619|Oceanospirillales 135619|Oceanospirillales F Carbamoyl-phosphate synthetase ammonia chain carB - 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS k141_2354_1 218284.CCDN010000001_gene176 9.39e-128 386.0 COG0318@1|root,COG0318@2|Bacteria,1V2NE@1239|Firmicutes,4HBPA@91061|Bacilli,1ZDIG@1386|Bacillus 91061|Bacilli IQ PFAM AMP-dependent synthetase and ligase - - - - - - - - - - - - - k141_21346_2 1042377.AFPJ01000052_gene1538 5.9e-56 180.0 COG1596@1|root,COG1596@2|Bacteria,1MXYS@1224|Proteobacteria,1SC60@1236|Gammaproteobacteria,467H9@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG1596 Periplasmic protein involved in polysaccharide export gumB - - ko:K20988 ko05111,map05111 - - - ko00000,ko00001,ko02000 1.B.18 - - Poly_export,SLBB k141_33270_1 1123279.ATUS01000001_gene2577 8.63e-78 241.0 COG0300@1|root,COG0300@2|Bacteria,1R9VQ@1224|Proteobacteria,1S1WG@1236|Gammaproteobacteria,1J9II@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S KR domain - - - - - - - - - - - - adh_short k141_33270_2 1453501.JELR01000002_gene1277 1.42e-200 570.0 COG0281@1|root,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,1RQ11@1236|Gammaproteobacteria,465JN@72275|Alteromonadaceae 1236|Gammaproteobacteria C malic enzyme maeA GO:0003674,GO:0003824,GO:0004470,GO:0004471,GO:0004473,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006094,GO:0006108,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016051,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0019318,GO:0019319,GO:0019752,GO:0032787,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0055114,GO:0071704,GO:1901576 1.1.1.38,1.1.1.40 ko:K00027,ko:K00029 ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020 M00169,M00172 R00214,R00216 RC00105 ko00000,ko00001,ko00002,ko01000 - - iSbBS512_1146.SbBS512_E1742 Malic_M,malic k141_36650_1 315730.BcerKBAB4_0321 1.13e-23 99.4 COG1757@1|root,COG1757@2|Bacteria,1TQ3B@1239|Firmicutes,4HA18@91061|Bacilli,1ZBQN@1386|Bacillus 91061|Bacilli C Na H antiporter nhaC_2 - - ko:K03315 - - - - ko00000,ko02000 2.A.35 - - Na_H_antiporter k141_31765_1 1453501.JELR01000002_gene485 1.01e-126 369.0 COG2365@1|root,COG2365@2|Bacteria,1R4XF@1224|Proteobacteria,1RMPM@1236|Gammaproteobacteria,466PW@72275|Alteromonadaceae 1236|Gammaproteobacteria T Tyrosine phosphatase family - - - - - - - - - - - - Y_phosphatase3 k141_21348_1 1502724.FF80_02678 1.87e-06 50.8 29CEM@1|root,2ZZD2@2|Bacteria,1RB3W@1224|Proteobacteria,2TVUB@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_4739_1 935836.JAEL01000083_gene1125 4.17e-10 59.3 COG2186@1|root,COG2186@2|Bacteria,1V2TU@1239|Firmicutes,4HDHI@91061|Bacilli,1ZD1T@1386|Bacillus 91061|Bacilli K COG2186 Transcriptional regulators yvfI - - ko:K05799 - - - - ko00000,ko03000 - - - FCD,GntR k141_36651_1 218284.CCDN010000001_gene549 2.36e-121 350.0 COG0566@1|root,COG0566@2|Bacteria,1V3JP@1239|Firmicutes,4HCF5@91061|Bacilli,1ZBTY@1386|Bacillus 91061|Bacilli J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family spoU - - ko:K03437 - - - - ko00000,ko03016 - - - SpoU_methylase,SpoU_sub_bind k141_31766_1 1499967.BAYZ01000171_gene5533 1.17e-66 225.0 COG0589@1|root,COG0589@2|Bacteria 2|Bacteria T AMP binding - - - - - - - - - - - - Usp k141_28388_1 1348635.BBJY01000001_gene2391 1.32e-121 354.0 COG2370@1|root,COG2370@2|Bacteria,1MV6Z@1224|Proteobacteria,1RRHA@1236|Gammaproteobacteria,1XW0Z@135623|Vibrionales 135623|Vibrionales O HupE / UreJ protein - - - - - - - - - - - - HupE_UreJ_2 k141_28388_2 1348635.BBJY01000001_gene2396 2.81e-132 383.0 COG0583@1|root,COG0583@2|Bacteria,1NUYD@1224|Proteobacteria,1SNQS@1236|Gammaproteobacteria,1XVQE@135623|Vibrionales 135623|Vibrionales K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_28388_3 1348635.BBJY01000001_gene2395 1.16e-285 783.0 COG0641@1|root,COG0641@2|Bacteria,1MX3M@1224|Proteobacteria,1RN4R@1236|Gammaproteobacteria,1XSAW@135623|Vibrionales 1236|Gammaproteobacteria C Iron-sulfur cluster-binding domain - - - ko:K06871 - - - - ko00000 - - - Fer4_12,Radical_SAM,SPASM k141_28388_4 1348635.BBJY01000001_gene2394 3.06e-283 790.0 COG3119@1|root,COG3119@2|Bacteria,1MV92@1224|Proteobacteria,1RPDE@1236|Gammaproteobacteria,1XWJ5@135623|Vibrionales 135623|Vibrionales P Sulfatase - - 3.1.6.1 ko:K01130 ko00140,ko00600,map00140,map00600 - R03980,R04856 RC00128,RC00231 ko00000,ko00001,ko01000 - - - Sulfatase k141_21349_1 1294265.JCM21738_2033 6.11e-76 240.0 COG0840@1|root,COG0840@2|Bacteria,1V0SD@1239|Firmicutes,4HD8P@91061|Bacilli,1ZCT0@1386|Bacillus 91061|Bacilli NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - - - - - - - - - - MCPsignal k141_16636_1 1485545.JQLW01000005_gene1179 1.29e-61 204.0 28HPH@1|root,2Z7XH@2|Bacteria,1Q80I@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_36652_1 1131730.BAVI_00165 3.92e-56 181.0 COG0454@1|root,COG0456@2|Bacteria,1V6CE@1239|Firmicutes,4HISU@91061|Bacilli,1ZGGP@1386|Bacillus 91061|Bacilli K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_4 k141_36652_2 406124.ACPC01000019_gene3055 5.94e-28 105.0 COG1051@1|root,COG1051@2|Bacteria,1V3T8@1239|Firmicutes,4HH2F@91061|Bacilli 91061|Bacilli F Belongs to the Nudix hydrolase family - - 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - - NUDIX k141_33274_1 1034347.CAHJ01000021_gene3364 2.79e-87 270.0 COG0477@1|root,COG2814@2|Bacteria,1U72T@1239|Firmicutes,4HCHH@91061|Bacilli,1ZCHP@1386|Bacillus 91061|Bacilli EGP COG0477 Permeases of the major facilitator superfamily ykuC - - - - - - - - - - - MFS_1 k141_15316_1 218284.CCDN010000001_gene523 4.47e-93 277.0 COG0745@1|root,COG0745@2|Bacteria,1TPWS@1239|Firmicutes,4H9KP@91061|Bacilli,1ZBGS@1386|Bacillus 91061|Bacilli T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain phoP - - ko:K07658 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C k141_2358_1 591158.SSMG_03098 5.02e-24 103.0 COG0458@1|root,COG0458@2|Bacteria,2GKXY@201174|Actinobacteria 201174|Actinobacteria EF Pfam Carbamoyl-phosphate synthase L chain, ATP binding domain - - - - - - - - - - - - ATP-grasp_4 k141_36653_2 981383.AEWH01000024_gene2811 6.06e-11 57.8 COG3655@1|root,COG3655@2|Bacteria,1VESP@1239|Firmicutes,4HKR7@91061|Bacilli 91061|Bacilli K Transcriptional regulator yozG - - ko:K07727 - - - - ko00000,ko03000 - - - HTH_26 k141_21351_1 265729.GS18_0213670 1.24e-32 119.0 COG0586@1|root,COG0586@2|Bacteria,1UV4D@1239|Firmicutes,4I3NC@91061|Bacilli,1ZN7J@1386|Bacillus 91061|Bacilli S Pfam SNARE associated Golgi protein - - - - - - - - - - - - - k141_33275_1 218284.CCDN010000003_gene2995 1.51e-69 216.0 2BYDV@1|root,32RAH@2|Bacteria,1V91M@1239|Firmicutes,4HIIQ@91061|Bacilli,1ZH7H@1386|Bacillus 91061|Bacilli S spore cortex biosynthesis protein yabQ GO:0005575,GO:0005623,GO:0042601,GO:0042763,GO:0044464 - - - - - - - - - - Spore_YabQ k141_28391_1 218284.CCDN010000001_gene594 2.8e-106 327.0 COG0466@1|root,COG0466@2|Bacteria,1TNYG@1239|Firmicutes,4HAZK@91061|Bacilli,1ZAXX@1386|Bacillus 91061|Bacilli O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner lon GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.4.21.53 ko:K01338 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - AAA,LON_substr_bdg,Lon_C k141_32186_1 163908.KB235896_gene2782 1.62e-11 69.3 COG1680@1|root,COG1680@2|Bacteria,1G4D0@1117|Cyanobacteria,1HRAP@1161|Nostocales 1117|Cyanobacteria V Beta-lactamase - - - - - - - - - - - - Beta-lactamase k141_13241_2 717772.THIAE_08285 2.65e-25 102.0 COG3201@1|root,COG3201@2|Bacteria,1MXN4@1224|Proteobacteria,1RMZE@1236|Gammaproteobacteria,4628B@72273|Thiotrichales 72273|Thiotrichales H Nicotinamide mononucleotide transporter - - - ko:K03811 - - - - ko00000,ko02000 4.B.1.1 - - NMN_transporter k141_1249_1 1384057.CD33_04090 8.42e-42 148.0 COG4980@1|root,COG4980@2|Bacteria,1VKVJ@1239|Firmicutes,4HRQ8@91061|Bacilli 91061|Bacilli S gas vesicle protein - - - - - - - - - - - - - k141_6101_2 1042377.AFPJ01000032_gene2821 3.61e-96 281.0 COG0835@1|root,COG0835@2|Bacteria,1RCIR@1224|Proteobacteria,1S61F@1236|Gammaproteobacteria,467KR@72275|Alteromonadaceae 1236|Gammaproteobacteria NT COG0835 Chemotaxis signal transduction protein pilI - - ko:K02659 ko02020,ko02025,map02020,map02025 - - - ko00000,ko00001,ko02035,ko02044 - - - CheW k141_31057_1 1415630.U771_16895 8.48e-43 149.0 COG0454@1|root,COG0454@2|Bacteria 2|Bacteria K -acetyltransferase - - 2.3.1.82 ko:K03830,ko:K18816 - - - - br01600,ko00000,ko01000,ko01504 - - - Acetyltransf_1,Acetyltransf_10,Acetyltransf_4 k141_22728_1 926561.KB900617_gene1633 7.63e-26 102.0 COG3541@1|root,COG3541@2|Bacteria,1TT57@1239|Firmicutes,24EJG@186801|Clostridia 186801|Clostridia S Predicted nucleotidyltransferase - - - ko:K07074 - - - - ko00000 - - - Nuc-transf k141_27432_1 218284.CCDN010000001_gene214 5.45e-90 271.0 COG4325@1|root,COG4325@2|Bacteria,1TSID@1239|Firmicutes,4HDM1@91061|Bacilli,1ZE04@1386|Bacillus 91061|Bacilli S Predicted membrane protein (DUF2254) - - - - - - - - - - - - DUF2254 k141_2518_1 218284.CCDN010000007_gene3908 7.29e-138 400.0 COG3314@1|root,COG3314@2|Bacteria,1TR35@1239|Firmicutes,4HAB6@91061|Bacilli,1ZARZ@1386|Bacillus 91061|Bacilli S protein conserved in bacteria - - - - - - - - - - - - Gate k141_21565_1 506534.Rhein_2853 2.28e-52 171.0 COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,1SYJN@1236|Gammaproteobacteria,1X2JJ@135613|Chromatiales 135613|Chromatiales V ABC transporter - - - - - - - - - - - - ABC_tran k141_21565_2 1279017.AQYJ01000025_gene630 1.15e-10 60.8 COG0577@1|root,COG0577@2|Bacteria,1PIKV@1224|Proteobacteria,1SYRG@1236|Gammaproteobacteria,466C2@72275|Alteromonadaceae 1236|Gammaproteobacteria V MacB-like periplasmic core domain - - - - - - - - - - - - FtsX,MacB_PCD k141_26303_1 218284.CCDN010000001_gene605 7.5e-37 134.0 COG0001@1|root,COG0001@2|Bacteria,1TPNH@1239|Firmicutes,4HANQ@91061|Bacilli,1ZBUT@1386|Bacillus 91061|Bacilli H Glutamate-1-semialdehyde aminotransferase hemL - 5.4.3.8 ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02272 RC00677 ko00000,ko00001,ko00002,ko01000,ko01007 - - iSB619.SA_RS08395 Aminotran_3 k141_28686_1 1340434.AXVA01000008_gene3644 8.26e-48 160.0 COG1802@1|root,COG1802@2|Bacteria,1TSV2@1239|Firmicutes,4HATG@91061|Bacilli,1ZCQY@1386|Bacillus 91061|Bacilli K FCD - - - - - - - - - - - - FCD,GntR k141_7244_1 1196031.ALEG01000034_gene5357 1.68e-59 198.0 COG3428@1|root,COG3428@2|Bacteria,1TSRJ@1239|Firmicutes,4HB8P@91061|Bacilli,1ZBIF@1386|Bacillus 91061|Bacilli S Membrane ydbT - - ko:K08981 - - - - ko00000 - - - bPH_2 k141_27433_1 997296.PB1_17089 5.78e-86 262.0 COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,4H9NG@91061|Bacilli,1ZCFZ@1386|Bacillus 91061|Bacilli K catabolite control protein A ccpA GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 k141_22729_1 218284.CCDN010000008_gene4032 4.99e-71 230.0 COG1785@1|root,COG1785@2|Bacteria,1TQCI@1239|Firmicutes,4HA27@91061|Bacilli,1ZB3J@1386|Bacillus 91061|Bacilli P Belongs to the alkaline phosphatase family phoB - 3.1.3.1 ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 M00126 R02135,R04620 RC00017 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 - - - Alk_phosphatase,Cu_amine_oxidN1 k141_25059_1 1340434.AXVA01000005_gene4820 5.22e-14 71.2 COG1396@1|root,COG1396@2|Bacteria,1VK84@1239|Firmicutes 1239|Firmicutes K Transcriptional - - - - - - - - - - - - HTH_19,HTH_3 k141_34607_1 941449.dsx2_2410 1.01e-58 205.0 COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,42M8F@68525|delta/epsilon subdivisions,2WIU0@28221|Deltaproteobacteria,2M7WE@213115|Desulfovibrionales 28221|Deltaproteobacteria P ATPase, P-type (transporting), HAD superfamily, subfamily IC pacL - 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - - Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3 k141_34607_2 653733.Selin_1632 5.18e-06 50.1 COG0530@1|root,COG0530@2|Bacteria 2|Bacteria P calcium, potassium:sodium antiporter activity yrbG - - ko:K07301 - - - - ko00000,ko02000 2.A.19.5 - - Na_Ca_ex k141_15614_1 1042377.AFPJ01000032_gene2819 7.77e-98 322.0 COG0643@1|root,COG0745@1|root,COG2198@1|root,COG3115@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,COG2198@2|Bacteria,COG3115@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,4650G@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0643 Chemotaxis protein histidine kinase and related kinases chpA - - ko:K02487,ko:K06596 ko02020,ko02025,map02020,map02025 M00507 - - ko00000,ko00001,ko00002,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg k141_31058_1 1294265.JCM21738_5478 4.25e-75 244.0 COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H9SA@91061|Bacilli,1ZAXY@1386|Bacillus 91061|Bacilli M penicillin-binding protein pbp2A - 2.4.1.129,3.4.16.4 ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase k141_11998_1 1392498.JQLH01000001_gene3100 1.95e-69 236.0 COG4447@1|root,COG4447@2|Bacteria,4NEZQ@976|Bacteroidetes,1HWS9@117743|Flavobacteriia,2PI8X@252356|Maribacter 976|Bacteroidetes S cellulose binding - - - - - - - - - - - - Sortilin-Vps10 k141_16745_1 1453501.JELR01000001_gene2853 1.81e-82 258.0 COG0477@1|root,COG2814@2|Bacteria,1MVKJ@1224|Proteobacteria,1RMHJ@1236|Gammaproteobacteria,464EA@72275|Alteromonadaceae 1236|Gammaproteobacteria EGP Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family xylE GO:0003674,GO:0005215,GO:0005351,GO:0005402,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0008643,GO:0015075,GO:0015077,GO:0015078,GO:0015144,GO:0015145,GO:0015146,GO:0015148,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015519,GO:0015672,GO:0015749,GO:0015750,GO:0015753,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034219,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 - ko:K05548,ko:K08138,ko:K08139 ko04113,map04113 - - - ko00000,ko00001,ko02000 2.A.1.1,2.A.1.1.3,2.A.1.15 - iECIAI1_1343.ECIAI1_4259,iECSE_1348.ECSE_4322 Sugar_tr k141_14407_2 83406.HDN1F_26120 8.84e-42 142.0 COG0838@1|root,COG0838@2|Bacteria,1RGUT@1224|Proteobacteria,1S644@1236|Gammaproteobacteria,1J799@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoA - 1.6.5.3 ko:K00330 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q4 k141_14407_3 1279017.AQYJ01000023_gene3171 7.25e-97 286.0 COG0377@1|root,COG0377@2|Bacteria,1MUI2@1224|Proteobacteria,1RP4R@1236|Gammaproteobacteria,469EA@72275|Alteromonadaceae 1236|Gammaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoB - 1.6.5.3 ko:K00331 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q6 k141_17997_1 977880.RALTA_A0499 6.89e-61 198.0 COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,2VHNA@28216|Betaproteobacteria,1K09V@119060|Burkholderiaceae 28216|Betaproteobacteria L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage recA - - ko:K03553 ko03440,map03440 M00729 - - ko00000,ko00001,ko00002,ko03400 - - - RecA k141_20300_2 218284.CCDN010000010_gene4357 4.19e-53 167.0 COG0186@1|root,COG0186@2|Bacteria,1V9YC@1239|Firmicutes,4HKDN@91061|Bacilli,1ZH2Q@1386|Bacillus 91061|Bacilli J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA rpsQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02961 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S17 k141_20300_3 545693.BMQ_0148 1.8e-77 231.0 COG0093@1|root,COG0093@2|Bacteria,1V3N0@1239|Firmicutes,4HGYR@91061|Bacilli,1ZG7H@1386|Bacillus 91061|Bacilli J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome rplN GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - ko:K02874 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L14 k141_20300_4 218284.CCDN010000010_gene4355 1.38e-63 194.0 COG0198@1|root,COG0198@2|Bacteria,1V9ZQ@1239|Firmicutes,4HKH9@91061|Bacilli,1ZGZQ@1386|Bacillus 91061|Bacilli J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit rplX GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02895 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KOW,ribosomal_L24 k141_36941_1 218284.CCDN010000006_gene3596 6e-157 453.0 COG2132@1|root,COG2132@2|Bacteria,1TQJK@1239|Firmicutes,4IRUW@91061|Bacilli,1ZBEQ@1386|Bacillus 91061|Bacilli Q Multi-copper - - - - - - - - - - - - Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3,Cupredoxin_1 k141_6103_1 1453501.JELR01000001_gene2941 1.12e-194 567.0 COG3525@1|root,COG3525@2|Bacteria,1MVDE@1224|Proteobacteria,1RMNI@1236|Gammaproteobacteria,465K7@72275|Alteromonadaceae 1236|Gammaproteobacteria G Putative carbohydrate binding domain chb - 3.2.1.52 ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 M00079 R00022,R06004,R11316 RC00049 ko00000,ko00001,ko00002,ko01000,ko03110 - GH20 - CHB_HEX,CHB_HEX_C,Glyco_hydro_20,Glyco_hydro_20b k141_23865_1 218284.CCDN010000004_gene3024 6.3e-130 390.0 COG2183@1|root,COG2183@2|Bacteria,1TPFE@1239|Firmicutes,4HAGY@91061|Bacilli,1ZC3T@1386|Bacillus 91061|Bacilli K COG2183 Transcriptional accessory protein tex - - ko:K06959 - - - - ko00000 - - - HHH_3,S1,Tex_N,Tex_YqgF k141_10791_1 1279017.AQYJ01000026_gene58 6.61e-239 739.0 COG1361@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4932@2|Bacteria,1R5G4@1224|Proteobacteria,1SEWA@1236|Gammaproteobacteria,469S7@72275|Alteromonadaceae 1236|Gammaproteobacteria M Domain of unknown function DUF11 - - - - - - - - - - - - DUF11,SdrD_B k141_26304_1 1279017.AQYJ01000029_gene3341 8.85e-16 75.5 COG0258@1|root,COG0258@2|Bacteria,1RAAR@1224|Proteobacteria,1RN1S@1236|Gammaproteobacteria,466M5@72275|Alteromonadaceae 1236|Gammaproteobacteria L Helix-hairpin-helix class 2 (Pol1 family) motifs exo - - - - - - - - - - - 5_3_exonuc,5_3_exonuc_N k141_26304_2 1279017.AQYJ01000029_gene3340 9.64e-83 249.0 COG3101@1|root,COG3101@2|Bacteria,1MWTG@1224|Proteobacteria,1RNHD@1236|Gammaproteobacteria,4678B@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria yfcM GO:0003674,GO:0003824,GO:0004497,GO:0005488,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016705,GO:0016709,GO:0017185,GO:0018126,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046872,GO:0055114,GO:0071704,GO:0072580,GO:1901260,GO:1901564 - ko:K09906 - - - - ko00000,ko01000,ko03012 - - - EpmC k141_27434_1 406124.ACPC01000005_gene3519 7.45e-69 223.0 COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TSKR@1239|Firmicutes,4H9R5@91061|Bacilli,1ZDUE@1386|Bacillus 91061|Bacilli T COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain - - - ko:K07720 ko02020,map02020 M00519 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_18,HTH_AraC,Response_reg k141_15615_1 1209072.ALBT01000038_gene2301 1.55e-89 288.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MV8W@1224|Proteobacteria,1RMQA@1236|Gammaproteobacteria,1FGRS@10|Cellvibrio 1236|Gammaproteobacteria P Outer membrane protein beta-barrel family - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_170_1 218284.CCDN010000001_gene609 6.72e-127 385.0 COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,4HB85@91061|Bacilli,1ZAS4@1386|Bacillus 91061|Bacilli J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner valS GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 k141_6104_1 1042377.AFPJ01000024_gene788 2.73e-115 342.0 COG0548@1|root,COG1246@1|root,COG0548@2|Bacteria,COG1246@2|Bacteria,1MUUP@1224|Proteobacteria,1RMV5@1236|Gammaproteobacteria,46457@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the acetyltransferase family. ArgA subfamily argA GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1 ko:K14682 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R00259 RC00004,RC00064 ko00000,ko00001,ko00002,ko01000 - - iECP_1309.ECP_2830,iLF82_1304.LF82_0116,iNRG857_1313.NRG857_13920,iYL1228.KPN_03226 AA_kinase,Acetyltransf_1 k141_33399_1 1294265.JCM21738_2820 1.43e-155 451.0 COG1164@1|root,COG1164@2|Bacteria,1TR7D@1239|Firmicutes,4HA0P@91061|Bacilli,1ZBBH@1386|Bacillus 91061|Bacilli E oligoendopeptidase F pepF1_3 - - - - - - - - - - - Peptidase_M3,Peptidase_M3_N k141_7247_1 223926.28808936 4.89e-219 610.0 COG2223@1|root,COG2223@2|Bacteria,1MWC7@1224|Proteobacteria,1S1CV@1236|Gammaproteobacteria,1XU0C@135623|Vibrionales 135623|Vibrionales P oxalate formate antiporter - - - - - - - - - - - - MFS_1 k141_26305_1 1294265.JCM21738_2886 4.36e-70 213.0 2E4ER@1|root,32Z9X@2|Bacteria,1VGCA@1239|Firmicutes,4HS6U@91061|Bacilli,1ZJ5Y@1386|Bacillus 91061|Bacilli - - yqzD - - - - - - - - - - - Sigma70_r4_2 k141_22730_1 1294265.JCM21738_3745 3.13e-77 230.0 COG0203@1|root,COG0203@2|Bacteria,1V6JQ@1239|Firmicutes,4HGX2@91061|Bacilli,1ZG80@1386|Bacillus 91061|Bacilli J Ribosomal protein L17 rplQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02879 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L17 k141_34609_1 1274524.BSONL12_04369 2.31e-37 137.0 COG0305@1|root,COG0305@2|Bacteria,1UYF2@1239|Firmicutes,4HF6Q@91061|Bacilli 91061|Bacilli L DnaB-like helicase C terminal domain - - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - AAA_25,DnaB_C k141_14410_1 441769.ABFU01000013_gene2458 6.63e-80 252.0 COG0591@1|root,COG0591@2|Bacteria,1TPVE@1239|Firmicutes,4H9KW@91061|Bacilli,1ZB64@1386|Bacillus 91061|Bacilli E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - ko:K11928 - - - - ko00000,ko02000 2.A.21.2 - - SSF k141_25061_1 218284.CCDN010000001_gene395 2.41e-84 253.0 COG1335@1|root,COG1335@2|Bacteria,1V347@1239|Firmicutes,4HGFM@91061|Bacilli,1ZG37@1386|Bacillus 91061|Bacilli Q Isochorismatase family entB - - - - - - - - - - - Isochorismatase k141_15616_1 886293.Sinac_0637 3.35e-43 150.0 COG1215@1|root,COG1215@2|Bacteria,2IXXE@203682|Planctomycetes 203682|Planctomycetes M PFAM Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 k141_6105_1 1441930.Z042_23145 3.8e-19 84.7 2D1MV@1|root,32TAZ@2|Bacteria,1N45A@1224|Proteobacteria,1S954@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage protein (N4 Gp49/phage Sf6 gene 66) family - - - - - - - - - - - - DUF2829,Phage_gp49_66 k141_6105_2 1283337.B0ZSJ4_BPHA1 3.19e-41 140.0 4QCCM@10239|Viruses,4QXI0@35237|dsDNA viruses no RNA stage,4QQTA@28883|Caudovirales,4QK0R@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k141_26337_1 218284.CCDN010000004_gene3044 2.08e-91 281.0 COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,4HACR@91061|Bacilli,1ZCC3@1386|Bacillus 91061|Bacilli M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein murF - 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 - R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M k141_26337_2 218284.CCDN010000004_gene3043 8.54e-30 111.0 COG1647@1|root,COG1647@2|Bacteria,1TVX4@1239|Firmicutes,4HFF2@91061|Bacilli,1ZD8C@1386|Bacillus 91061|Bacilli S COG1647 Esterase lipase - - 3.1.1.1 ko:K03928 - - - - ko00000,ko01000 - - - Abhydrolase_1,Hydrolase_4 k141_6139_2 1042377.AFPJ01000043_gene845 1.02e-98 296.0 COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,1RNIR@1236|Gammaproteobacteria,464PA@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG0332 3-oxoacyl- acyl-carrier-protein synthase III fabH - 2.3.1.207 ko:K16872 - - - - ko00000,ko01000 - - - ACP_syn_III,ACP_syn_III_C k141_1276_1 1453501.JELR01000002_gene1177 4.75e-120 353.0 COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,1RPV9@1236|Gammaproteobacteria,46535@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0581 ABC-type phosphate transport system, permease component pstA - - ko:K02038 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1,DUF3333 k141_27454_2 223926.28807924 1.91e-116 343.0 COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,1RNS4@1236|Gammaproteobacteria,1XT9Q@135623|Vibrionales 135623|Vibrionales F Belongs to the GARS family purD GO:0003674,GO:0003824,GO:0004637,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.13 ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144 RC00090,RC00166 ko00000,ko00001,ko00002,ko01000 - - - GARS_A,GARS_C,GARS_N k141_21583_1 1121938.AUDY01000008_gene1664 6.91e-17 83.6 COG0860@1|root,COG0860@2|Bacteria,1V4B9@1239|Firmicutes,4HGZ9@91061|Bacilli,3NEVJ@45667|Halobacillus 91061|Bacilli M Ami_3 - - 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - Amidase_3,PG_binding_1,SPOR k141_21583_2 1347087.CBYO010000011_gene1803 1.74e-09 55.5 2DRCI@1|root,33B7V@2|Bacteria,1VKC1@1239|Firmicutes,4HP5W@91061|Bacilli 91061|Bacilli S SPP1 phage holin xhlB - - - - - - - - - - - Holin_SPP1 k141_16779_1 218284.CCDN010000003_gene2991 1.85e-40 148.0 COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,4HACG@91061|Bacilli,1ZBBF@1386|Bacillus 91061|Bacilli S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid yabM GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03328 - - - - ko00000 2.A.66.2 - - Polysacc_synt,Polysacc_synt_C k141_2543_1 42565.FP66_06975 7.47e-254 708.0 COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,1QTTG@1224|Proteobacteria,1RNG6@1236|Gammaproteobacteria,1XIFS@135619|Oceanospirillales 135619|Oceanospirillales CI Oxaloacetate decarboxylase oadA - 4.1.1.3 ko:K01571 ko00620,ko01100,map00620,map01100 - R00217 RC00040 ko00000,ko00001,ko01000,ko02000 3.B.1.1.1 - - Biotin_lipoyl,HMGL-like,PYC_OADA k141_36960_1 1042377.AFPJ01000028_gene2280 1.02e-121 351.0 COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,1RP86@1236|Gammaproteobacteria,466E7@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the UPF0758 family radC GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - ko:K03630 - - - - ko00000 - - - RadC k141_36960_2 1279017.AQYJ01000027_gene1897 2.34e-202 570.0 COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,1RMKQ@1236|Gammaproteobacteria,464IR@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine coaBC GO:0000166,GO:0003674,GO:0003824,GO:0004632,GO:0004633,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0010181,GO:0015936,GO:0015937,GO:0016829,GO:0016830,GO:0016831,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032553,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.1.1.36,6.3.2.5 ko:K13038 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 - - iEC042_1314.EC042_3945,iECUMN_1333.ECUMN_4154,iJN746.PP_5285,iSBO_1134.SBO_3641 DFP,Flavoprotein k141_36960_3 1279017.AQYJ01000027_gene1896 1.26e-315 888.0 COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,1RMU8@1236|Gammaproteobacteria,46404@72275|Alteromonadaceae 1236|Gammaproteobacteria G Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II algC GO:0003674,GO:0003824,GO:0004615,GO:0005975,GO:0008150,GO:0008152,GO:0016853,GO:0016866,GO:0016868,GO:0044238,GO:0071704 5.4.2.2,5.4.2.8 ko:K01840,ko:K15778 ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00114 R00959,R01057,R01818,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV k141_36960_4 1042377.AFPJ01000028_gene2283 7.7e-189 528.0 COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,1RNKK@1236|Gammaproteobacteria,464HG@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the acetylglutamate kinase family. ArgB subfamily argB GO:0003674,GO:0003824,GO:0003991,GO:0004042,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016407,GO:0016410,GO:0016597,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0033554,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.7.2.8 ko:K00930,ko:K22478 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R00259,R02649 RC00002,RC00004,RC00043,RC00064 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_2508,iB21_1397.B21_03793,iEC55989_1330.EC55989_4441,iECB_1328.ECB_03844,iECDH10B_1368.ECDH10B_4147,iECDH1ME8569_1439.ECDH1ME8569_3827,iECD_1391.ECD_03844,iECH74115_1262.ECH74115_5419,iECIAI1_1343.ECIAI1_4167,iECO103_1326.ECO103_4715,iECOK1_1307.ECOK1_4431,iECS88_1305.ECS88_4414,iECSE_1348.ECSE_4252,iETEC_1333.ETEC_4227,iEcE24377_1341.EcE24377A_4498,iEcHS_1320.EcHS_A4193,iEcolC_1368.EcolC_4057,iSbBS512_1146.SbBS512_E4445,iUMN146_1321.UM146_20050,iUMNK88_1353.UMNK88_4797,iUTI89_1310.UTI89_C4550,iY75_1357.Y75_RS17255 AA_kinase,NAT k141_36960_5 1279017.AQYJ01000027_gene1894 1.49e-124 357.0 COG1309@1|root,COG1309@2|Bacteria,1MWF7@1224|Proteobacteria,1RPZ6@1236|Gammaproteobacteria,465HE@72275|Alteromonadaceae 1236|Gammaproteobacteria D Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions slmA GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000918,GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0007049,GO:0007346,GO:0008150,GO:0009295,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0010564,GO:0010948,GO:0010974,GO:0016043,GO:0019219,GO:0019222,GO:0022402,GO:0022607,GO:0031323,GO:0031326,GO:0031333,GO:0032271,GO:0032272,GO:0032465,GO:0032466,GO:0032506,GO:0032954,GO:0032955,GO:0042802,GO:0043085,GO:0043087,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043254,GO:0043547,GO:0043565,GO:0043590,GO:0044085,GO:0044087,GO:0044093,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0045786,GO:0045930,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051252,GO:0051301,GO:0051302,GO:0051336,GO:0051345,GO:0051726,GO:0051782,GO:0060255,GO:0061640,GO:0065007,GO:0065009,GO:0071840,GO:0080090,GO:0090529,GO:0097159,GO:0140110,GO:1901363,GO:1901891,GO:1901892,GO:1902410,GO:1902412,GO:1902413,GO:1903047,GO:1903436,GO:1903437,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - ko:K05501 - - - - ko00000,ko03000,ko03036 - - - TetR_N k141_36960_6 1042377.AFPJ01000028_gene2285 3.36e-66 208.0 COG2433@1|root,COG2433@2|Bacteria,1N0ZS@1224|Proteobacteria,1SBFE@1236|Gammaproteobacteria,46CTE@72275|Alteromonadaceae 1236|Gammaproteobacteria S Pfam Transposase IS66 - - - - - - - - - - - - - k141_7274_2 218284.CCDN010000001_gene139 2.36e-80 241.0 COG3576@1|root,COG3576@2|Bacteria,1V3YD@1239|Firmicutes,4HH46@91061|Bacilli,1ZG6P@1386|Bacillus 91061|Bacilli S Pyridoxamine 5'-phosphate oxidase - - - - - - - - - - - - Putative_PNPOx k141_34628_2 1042377.AFPJ01000028_gene2207 3.49e-42 150.0 COG5002@1|root,COG5002@2|Bacteria,1NWB7@1224|Proteobacteria,1SPHN@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Sensory histidine kinase in two-component regulatory system with RstA - - 2.7.13.3 ko:K02484,ko:K07639,ko:K18143 ko01501,ko02020,map01501,map02020 M00446,M00649,M00655 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 - - - HATPase_c,HisKA k141_26338_1 1127673.GLIP_0143 2.97e-41 151.0 COG3214@1|root,COG3214@2|Bacteria,1N40B@1224|Proteobacteria,1RPYB@1236|Gammaproteobacteria,469ZV@72275|Alteromonadaceae 1236|Gammaproteobacteria S Winged helix DNA-binding domain ycaQ - - ko:K09927 - - - - ko00000 - - - HTH_42 k141_3740_1 1145276.T479_18560 2.68e-06 48.1 COG1051@1|root,COG1051@2|Bacteria,1V4TX@1239|Firmicutes,4HH70@91061|Bacilli,3IW3E@400634|Lysinibacillus 91061|Bacilli F Belongs to the Nudix hydrolase family - - - - - - - - - - - - NUDIX k141_6141_1 1347086.CCBA010000010_gene1902 7.24e-113 327.0 COG4912@1|root,COG4912@2|Bacteria,1UP0J@1239|Firmicutes,4HDFV@91061|Bacilli,1ZBU5@1386|Bacillus 91061|Bacilli L DNA alkylation repair enzyme - - - - - - - - - - - - DNA_alkylation k141_26339_1 218284.CCDN010000005_gene3434 3.84e-93 287.0 COG0260@1|root,COG0260@2|Bacteria,1TPJZ@1239|Firmicutes,4HAPW@91061|Bacilli,1ZBZU@1386|Bacillus 91061|Bacilli E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides pepA - 3.4.11.1 ko:K01255 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - Peptidase_M17,Peptidase_M17_N k141_36962_1 1294265.JCM21738_5163 4.01e-109 319.0 COG4990@1|root,COG4990@2|Bacteria,1V6DF@1239|Firmicutes,4IPKV@91061|Bacilli,1ZRC4@1386|Bacillus 91061|Bacilli M Peptidase_C39 like family - - - - - - - - - - - - Peptidase_C39_2 k141_18030_1 1453501.JELR01000001_gene2215 1.4e-81 246.0 COG0398@1|root,COG0398@2|Bacteria,1MVF3@1224|Proteobacteria,1S5SK@1236|Gammaproteobacteria,468K2@72275|Alteromonadaceae 1236|Gammaproteobacteria S SNARE associated Golgi protein - - - - - - - - - - - - SNARE_assoc k141_31093_1 406124.ACPC01000009_gene1466 8.06e-97 292.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4HASW@91061|Bacilli,1ZB29@1386|Bacillus 91061|Bacilli I Belongs to the thiolase family - - 2.3.1.16,2.3.1.9 ko:K00626,ko:K00632 ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00087,M00088,M00095,M00113,M00373,M00374,M00375 R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095 RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N k141_28718_1 1347086.CCBA010000031_gene1009 1.14e-125 379.0 COG0296@1|root,COG0296@2|Bacteria,1TP4M@1239|Firmicutes,4HAPM@91061|Bacilli,1ZCHU@1386|Bacillus 91061|Bacilli G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position glgB GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901576 2.4.1.18 ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02110 - ko00000,ko00001,ko00002,ko01000,ko04147 - CBM48,GH13 - Alpha-amylase,Alpha-amylase_C,CBM_48 k141_33403_1 396588.Tgr7_0537 3.79e-42 145.0 COG0848@1|root,COG0848@2|Bacteria,1RENY@1224|Proteobacteria,1S3TB@1236|Gammaproteobacteria 1236|Gammaproteobacteria U biopolymer transport protein - - - - - - - - - - - - ExbD k141_206_1 443143.GM18_4470 2.17e-44 164.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2WIK8@28221|Deltaproteobacteria,43UE7@69541|Desulfuromonadales 28221|Deltaproteobacteria T Response regulator receiver modulated diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - - - - - - - - - - EAL,GGDEF,PAS_3,Response_reg k141_2544_1 218284.CCDN010000001_gene781 1.01e-128 380.0 COG0477@1|root,COG2814@2|Bacteria,1TQEW@1239|Firmicutes,4HASU@91061|Bacilli,1ZE6N@1386|Bacillus 91061|Bacilli EGP Sugar (and other) transporter - - - ko:K08221 - - - - ko00000,ko02000 2.A.1.32 - - MFS_1 k141_35765_1 218284.CCDN010000001_gene987 4.96e-121 358.0 COG0508@1|root,COG0508@2|Bacteria,1TQSH@1239|Firmicutes,4HBSU@91061|Bacilli,1ZC6F@1386|Bacillus 91061|Bacilli C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex bkdB - 2.3.1.12,2.3.1.168 ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 M00036,M00307 R00209,R02569,R02662,R03174,R04097,R10998 RC00004,RC02727,RC02742,RC02857,RC02870 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding k141_21725_1 218284.CCDN010000002_gene2230 4.09e-167 476.0 COG0654@1|root,COG0654@2|Bacteria,1U29G@1239|Firmicutes,4HF0P@91061|Bacilli,1ZE9I@1386|Bacillus 91061|Bacilli CH FAD binding domain - - - - - - - - - - - - FAD_binding_3 k141_34775_2 1444770.AF72_05755 2.27e-21 95.1 COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,1RNZE@1236|Gammaproteobacteria,1X4P4@135614|Xanthomonadales 135614|Xanthomonadales D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase tig GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K03545 - - - - ko00000 - - - FKBP_C,Trigger_C,Trigger_N k141_10990_1 218284.CCDN010000005_gene3225 3.91e-50 171.0 COG2356@1|root,COG4085@1|root,COG2356@2|Bacteria,COG4085@2|Bacteria,1U9GI@1239|Firmicutes,4IJKB@91061|Bacilli,1ZAYK@1386|Bacillus 91061|Bacilli L Ribonuclease bsn GO:0005575,GO:0005576 - - - - - - - - - - Endonuclease_1 k141_32324_1 218284.CCDN010000002_gene2222 1.72e-07 49.7 2BGZ1@1|root,32AZ5@2|Bacteria,1UB27@1239|Firmicutes,4IMF3@91061|Bacilli,1ZK06@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_410_1 1220589.CD32_17580 1.87e-65 215.0 COG0189@1|root,COG0189@2|Bacteria,1UZ79@1239|Firmicutes,4HDEG@91061|Bacilli 91061|Bacilli HJ Endospore coat-associated protein yheC5 - - - - - - - - - - - ATPgrasp_YheCD k141_19333_1 1294265.JCM21738_2293 1.39e-120 345.0 COG0500@1|root,COG2226@2|Bacteria,1UW6A@1239|Firmicutes,4HHM5@91061|Bacilli,1ZDRF@1386|Bacillus 91061|Bacilli Q ubiE/COQ5 methyltransferase family - - - - - - - - - - - - Methyltransf_11,Methyltransf_23 k141_19333_2 1294265.JCM21738_2294 2.38e-87 258.0 COG1633@1|root,COG1633@2|Bacteria,1V9AF@1239|Firmicutes,4HIP7@91061|Bacilli,1ZGFE@1386|Bacillus 91061|Bacilli S Rubrerythrin yhjR - - - - - - - - - - - DUF2202,Rubrerythrin k141_19333_3 1294265.JCM21738_2295 2.74e-13 68.2 COG3258@1|root,COG3258@2|Bacteria,1TSHS@1239|Firmicutes,4HBXB@91061|Bacilli,1ZN0Q@1386|Bacillus 91061|Bacilli C Cytochrome c - - 1.8.2.2 ko:K19713 - - - - ko00000,ko01000 - - - Cytochrom_C,Cytochrome_CBB3 k141_22965_1 218284.CCDN010000002_gene2144 1.02e-142 415.0 COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,4H9W6@91061|Bacilli,1ZD0J@1386|Bacillus 91061|Bacilli G Belongs to the FGGY kinase family gntK - 2.7.1.12 ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 - R01737 RC00002,RC00017 ko00000,ko00001,ko01000 - - - FGGY_C,FGGY_N k141_21739_1 1294265.JCM21738_148 2.15e-102 298.0 COG0414@1|root,COG0414@2|Bacteria,1TP7A@1239|Firmicutes,4HAIQ@91061|Bacilli,1ZAV5@1386|Bacillus 91061|Bacilli H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate panC GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 M00119 R02473 RC00096,RC00141 ko00000,ko00001,ko00002,ko01000 - - - Pantoate_ligase k141_25300_1 265729.GS18_0201065 4.29e-88 278.0 COG0376@1|root,COG0376@2|Bacteria,1TQDA@1239|Firmicutes,4HBZ5@91061|Bacilli,1ZD07@1386|Bacillus 91061|Bacilli P Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity katG - 1.11.1.21 ko:K03782 ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110 - R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906 RC00034,RC00213,RC00767,RC02141 ko00000,ko00001,ko01000 - - - peroxidase k141_29964_1 1123236.KB899386_gene1852 3.15e-112 334.0 COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,1RPM2@1236|Gammaproteobacteria,4657V@72275|Alteromonadaceae 1236|Gammaproteobacteria L it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins dnaB GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k141_8662_1 171693.BN988_02918 2.88e-120 369.0 COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,4H9SP@91061|Bacilli,23IKS@182709|Oceanobacillus 91061|Bacilli P Heavy-metal-associated domain - - 3.6.3.3,3.6.3.5 ko:K01534 - - - - ko00000,ko01000 3.A.3.6 - - E1-E2_ATPase,HMA,Hydrolase k141_24087_2 866895.HBHAL_2153 1.75e-59 198.0 COG0025@1|root,COG0025@2|Bacteria,1TR4G@1239|Firmicutes,4HBJR@91061|Bacilli,3NDWY@45667|Halobacillus 91061|Bacilli P Sodium/hydrogen exchanger family - - - ko:K03316 - - - - ko00000 2.A.36 - - Na_H_Exchanger k141_5083_1 406124.ACPC01000022_gene4097 1.65e-54 187.0 COG4325@1|root,COG4325@2|Bacteria,1TSID@1239|Firmicutes,4HDM1@91061|Bacilli,1ZE04@1386|Bacillus 91061|Bacilli S Predicted membrane protein (DUF2254) - - - - - - - - - - - - DUF2254 k141_33610_2 931276.Cspa_c22600 2.23e-25 107.0 COG3437@1|root,COG3437@2|Bacteria,1TQ0S@1239|Firmicutes,24800@186801|Clostridia,36E1T@31979|Clostridiaceae 186801|Clostridia T Diguanylate cyclase - - - - - - - - - - - - GGDEF,HD,HD_5 k141_7442_1 574376.BAMA_11815 9.66e-51 174.0 COG1173@1|root,COG1173@2|Bacteria 2|Bacteria P ABC-type dipeptide oligopeptide nickel transport systems, permease components - - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 k141_26660_1 218284.CCDN010000001_gene1219 7.21e-112 332.0 COG1509@1|root,COG1509@2|Bacteria,1TQQZ@1239|Firmicutes,4HE2P@91061|Bacilli,1ZBET@1386|Bacillus 91061|Bacilli E lysine 2,3-aminomutase kamA - 5.4.3.2 ko:K01843 ko00310,map00310 - R00461 RC00303 ko00000,ko00001,ko01000 - - - Fer4_12,Fer4_14,LAM_C,Radical_SAM k141_37106_1 1042377.AFPJ01000008_gene1957 2.01e-151 440.0 COG0654@1|root,COG0654@2|Bacteria,1NSGN@1224|Proteobacteria,1T22A@1236|Gammaproteobacteria,46D2U@72275|Alteromonadaceae 1236|Gammaproteobacteria CH Tryptophan halogenase - - 1.14.19.9 ko:K14266 ko00404,ko01130,map00404,map01130 M00789,M00790 R09570 RC00949 ko00000,ko00001,ko00002,ko01000 - - - Trp_halogenase k141_2735_1 218284.CCDN010000002_gene2215 7.52e-38 136.0 2BE93@1|root,32804@2|Bacteria,1UAWI@1239|Firmicutes,4IM9C@91061|Bacilli,1ZJIH@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_12327_1 1385511.N783_15510 7.95e-38 143.0 COG0457@1|root,COG0705@1|root,COG0457@2|Bacteria,COG0705@2|Bacteria,1TQXT@1239|Firmicutes,4HCDF@91061|Bacilli,2Y9FD@289201|Pontibacillus 91061|Bacilli S Rhomboid family gluP - 3.4.21.105 ko:K19225 - - - - ko00000,ko01000,ko01002 - - - Rhomboid,TPR_2,TPR_8 k141_22967_1 218284.CCDN010000005_gene3296 7.43e-46 149.0 2E3PJ@1|root,32YMN@2|Bacteria,1VGBJ@1239|Firmicutes,4HNU4@91061|Bacilli,1ZIVU@1386|Bacillus 91061|Bacilli S Belongs to the UPF0738 family yjbL - - - - - - - - - - - - k141_35940_1 1219076.N646_3504 4.29e-81 241.0 COG3791@1|root,COG3791@2|Bacteria,1RHWZ@1224|Proteobacteria,1S4HQ@1236|Gammaproteobacteria,1XXI2@135623|Vibrionales 135623|Vibrionales S Glutathione-dependent formaldehyde-activating enzyme - - - - - - - - - - - - GFA k141_35940_2 1116375.VEJY3_15936 9.79e-313 855.0 COG1055@1|root,COG1055@2|Bacteria,1MUH8@1224|Proteobacteria,1RPSM@1236|Gammaproteobacteria,1XTNI@135623|Vibrionales 135623|Vibrionales P COG1055 Na H antiporter NhaD and related arsenite permeases nhaD - - - - - - - - - - - CitMHS k141_8663_1 218284.CCDN010000001_gene156 3.54e-32 119.0 COG0497@1|root,COG0497@2|Bacteria,1V4G3@1239|Firmicutes,4HHDM@91061|Bacilli,1ZH4B@1386|Bacillus 91061|Bacilli L Putative cell-wall binding lipoprotein ykyA - - - - - - - - - - - YkyA k141_21740_1 1415778.JQMM01000001_gene2175 8.93e-83 258.0 COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,1RN6U@1236|Gammaproteobacteria,1J56Y@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits - - 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_N k141_431_1 1116375.VEJY3_15155 3.76e-11 62.0 COG2962@1|root,COG2962@2|Bacteria,1MX5G@1224|Proteobacteria,1RMAC@1236|Gammaproteobacteria,1XSTP@135623|Vibrionales 135623|Vibrionales S EamA-like transporter family rarD - - ko:K05786 - - - - ko00000,ko02000 2.A.7.7 - - EamA k141_431_2 1116375.VEJY3_15160 1.62e-182 509.0 COG4977@1|root,COG4977@2|Bacteria,1QUGK@1224|Proteobacteria,1RV41@1236|Gammaproteobacteria,1XUCU@135623|Vibrionales 135623|Vibrionales K Family transcriptional regulator - - - - - - - - - - - - AraC_binding,HTH_18 k141_431_3 674977.VMC_02080 3.72e-133 380.0 COG1280@1|root,COG1280@2|Bacteria,1MYC4@1224|Proteobacteria,1S64J@1236|Gammaproteobacteria,1XT1Y@135623|Vibrionales 135623|Vibrionales E threonine efflux protein - - - - - - - - - - - - LysE k141_9835_1 1294265.JCM21738_3099 6.11e-78 233.0 COG5506@1|root,COG5506@2|Bacteria,1VFCV@1239|Firmicutes,4HNNE@91061|Bacilli,1ZI9H@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF1694) XK27_05190 - - - - - - - - - - - DUF1694 k141_34798_2 218284.CCDN010000001_gene932 4.74e-76 228.0 COG2165@1|root,COG2165@2|Bacteria 2|Bacteria NU general secretion pathway protein - - - ko:K02246,ko:K02650,ko:K10924 ko02020,ko05111,map02020,map05111 M00429 - - ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15.2 - - N_methyl k141_34798_3 218284.CCDN010000001_gene931 6.84e-64 195.0 COG4537@1|root,COG4537@2|Bacteria,1VFI9@1239|Firmicutes,4HNNT@91061|Bacilli,1ZIXK@1386|Bacillus 91061|Bacilli U Required for transformation and DNA binding comGC GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944 - ko:K02245 - M00429 - - ko00000,ko00002,ko02044 - - - N_methyl k141_25301_1 1242864.D187_000068 3.3e-44 158.0 COG5505@1|root,COG5505@2|Bacteria,1MW87@1224|Proteobacteria,42RQH@68525|delta/epsilon subdivisions,2WTKY@28221|Deltaproteobacteria,2YTSF@29|Myxococcales 28221|Deltaproteobacteria S Protein of unknown function (DUF819) - - - - - - - - - - - - DUF819 k141_2736_1 1294265.JCM21738_1119 1.79e-113 332.0 COG4278@1|root,COG4278@2|Bacteria,1V9IZ@1239|Firmicutes,4HJ53@91061|Bacilli,1ZDIS@1386|Bacillus 91061|Bacilli H phenylacetate-CoA ligase activity - - - - - - - - - - - - - k141_19334_1 218284.CCDN010000002_gene2943 5.19e-160 452.0 COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4HBB9@91061|Bacilli,1ZC1H@1386|Bacillus 91061|Bacilli EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components dppC - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1,OppC_N k141_22969_1 1453501.JELR01000001_gene2502 2.75e-111 337.0 COG2304@1|root,COG2304@2|Bacteria,1MW51@1224|Proteobacteria,1RMD3@1236|Gammaproteobacteria,464YJ@72275|Alteromonadaceae 1236|Gammaproteobacteria K protein containing a von Willebrand factor type A (vWA) domain - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - TPR_1,TPR_2,VWA_2 k141_13479_2 1479237.JMLY01000001_gene3195 2.24e-155 442.0 COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,1RTDE@1236|Gammaproteobacteria,464ZV@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG0846 NAD-dependent protein deacetylases, SIR2 family cobB - - ko:K12410 - - - - ko00000,ko01000 - - - SIR2 k141_13479_4 1318628.MARLIPOL_10166 1.89e-178 500.0 COG0625@1|root,COG0625@2|Bacteria,1MUN3@1224|Proteobacteria,1RMF7@1236|Gammaproteobacteria,464IW@72275|Alteromonadaceae 1236|Gammaproteobacteria O Glutathione S-transferase yghU - - ko:K11209 - - - - ko00000,ko01000 - - - GST_C,GST_C_2,GST_N k141_5085_2 572477.Alvin_2570 8.74e-45 159.0 COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,1RMGJ@1236|Gammaproteobacteria,1WVWV@135613|Chromatiales 135613|Chromatiales Q TIGRFAM phytoene desaturase - - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 ko:K10027 ko00906,ko01100,ko01110,map00906,map01100,map01110 - R04787,R04798,R04800,R09691,R09692 RC01214,RC02088,RC02605 ko00000,ko00001,ko01000 - - - Amino_oxidase k141_9836_1 218284.CCDN010000005_gene3323 5.7e-25 97.8 COG4729@1|root,COG4729@2|Bacteria,1VCAR@1239|Firmicutes,4HM9T@91061|Bacilli,1ZE7Y@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF1850) - - - - - - - - - - - - DUF1850 k141_9836_2 218284.CCDN010000005_gene3324 1.03e-89 281.0 COG4666@1|root,COG4666@2|Bacteria,1TP0V@1239|Firmicutes,4HC4B@91061|Bacilli,1ZAWZ@1386|Bacillus 91061|Bacilli S Tripartite ATP-independent periplasmic transporter, DctM component siaT_4 - - - - - - - - - - - DUF3394,DctM k141_27589_1 218284.CCDN010000002_gene2211 1.49e-219 612.0 COG1972@1|root,COG1972@2|Bacteria,1TRSK@1239|Firmicutes,4I95Q@91061|Bacilli,1ZEBU@1386|Bacillus 91061|Bacilli F Na+ dependent nucleoside transporter C-terminus - - - ko:K03317 - - - - ko00000 2.A.41 - - Nucleos_tra2_C,Nucleos_tra2_N k141_14571_1 1121921.KB898709_gene98 2.99e-22 99.8 COG4977@1|root,COG4977@2|Bacteria,1QYME@1224|Proteobacteria 1224|Proteobacteria K helix_turn_helix, arabinose operon control protein - - - - - - - - - - - - HTH_18 k141_33612_1 218284.CCDN010000002_gene2154 1.14e-87 265.0 COG0702@1|root,COG0702@2|Bacteria,1V112@1239|Firmicutes,4HEVN@91061|Bacilli,1ZG8I@1386|Bacillus 91061|Bacilli GM NAD(P)H-binding M1-688 - - - - - - - - - - - Epimerase,HIM1,NAD_binding_10 k141_1474_1 1173023.KE650771_gene1274 7.81e-06 46.6 COG3655@1|root,COG3655@2|Bacteria,1GAW8@1117|Cyanobacteria 1117|Cyanobacteria K Cro/C1-type HTH DNA-binding domain - - - - - - - - - - - - HTH_26 k141_1474_2 1461580.CCAS010000067_gene4022 3.36e-47 158.0 COG3935@1|root,COG3935@2|Bacteria,1V99B@1239|Firmicutes,4HK5M@91061|Bacilli,1ZGD4@1386|Bacillus 91061|Bacilli L DnaD domain protein - - - - - - - - - - - - DnaB_2 k141_24088_1 218284.CCDN010000004_gene3121 9.18e-132 386.0 COG0591@1|root,COG0591@2|Bacteria,1TPVE@1239|Firmicutes,4H9KW@91061|Bacilli,1ZB64@1386|Bacillus 91061|Bacilli E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - ko:K11928 - - - - ko00000,ko02000 2.A.21.2 - - SSF k141_18225_5 1279017.AQYJ01000020_gene1229 1.36e-203 575.0 COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,1RMWS@1236|Gammaproteobacteria,4646Q@72275|Alteromonadaceae 1236|Gammaproteobacteria F COG0138 AICAR transformylase IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) purH GO:0003674,GO:0003824,GO:0004643,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 - - iEcHS_1320.EcHS_A4240,iPC815.YPO3728 AICARFT_IMPCHas,MGS k141_9837_1 1453501.JELR01000001_gene2680 9.75e-43 157.0 COG2208@1|root,COG3437@1|root,COG2208@2|Bacteria,COG3437@2|Bacteria,1N4K5@1224|Proteobacteria,1RNYP@1236|Gammaproteobacteria,4650J@72275|Alteromonadaceae 1236|Gammaproteobacteria T response regulator rsbU - - ko:K20977 ko02020,ko02025,map02020,map02025 M00820 - - ko00000,ko00001,ko00002,ko02022 - - - HATPase_c_2,Response_reg,SpoIIE k141_25302_1 218284.CCDN010000005_gene3178 1.24e-94 278.0 2CK8D@1|root,32SBU@2|Bacteria,1VAQG@1239|Firmicutes,4HHGS@91061|Bacilli,1ZF8Y@1386|Bacillus 91061|Bacilli S Tryptophan transporter TrpP trpP - - - - - - - - - - iYO844.BSU10010 TrpP k141_37108_2 218284.CCDN010000005_gene3495 8.5e-109 333.0 COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,1TPKU@1239|Firmicutes,4H9KR@91061|Bacilli,1ZAVB@1386|Bacillus 91061|Bacilli GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type) fruA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563 2.7.1.202 ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1 - - PTS_EIIA_2,PTS_EIIC,PTS_IIB k141_5086_1 861299.J421_4163 1.12e-16 85.5 COG0795@1|root,COG0795@2|Bacteria,1ZSNM@142182|Gemmatimonadetes 142182|Gemmatimonadetes S Predicted permease YjgP/YjgQ family - - - ko:K11720 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko02000 1.B.42.1 - - YjgP_YjgQ k141_7444_1 91464.S7335_1425 4.49e-43 153.0 COG1912@1|root,COG1912@2|Bacteria,1G1B1@1117|Cyanobacteria,1GYAI@1129|Synechococcus 1117|Cyanobacteria S S-adenosyl-l-methionine hydroxide adenosyltransferase - - - ko:K22205 - - - - ko00000,ko01000 - - - SAM_adeno_trans k141_11018_1 1279017.AQYJ01000027_gene1925 5.65e-276 758.0 COG0281@1|root,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,1RN5F@1236|Gammaproteobacteria,465MY@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG0281 Malic enzyme maeB - 1.1.1.38,1.1.1.40 ko:K00027,ko:K00029 ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020 M00169,M00172 R00214,R00216 RC00105 ko00000,ko00001,ko00002,ko01000 - - - Malic_M,malic k141_11018_2 1453501.JELR01000002_gene1248 4.36e-110 326.0 COG1525@1|root,COG1525@2|Bacteria,1RKRQ@1224|Proteobacteria,1S7UH@1236|Gammaproteobacteria,467WT@72275|Alteromonadaceae 1236|Gammaproteobacteria L Staphylococcal nuclease homologues - - - - - - - - - - - - SNase k141_11018_4 1279017.AQYJ01000027_gene1927 2e-188 545.0 COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,1RPZ7@1236|Gammaproteobacteria,464GR@72275|Alteromonadaceae 1236|Gammaproteobacteria L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA priA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006276,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0010332,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042221,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0046677,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - ko:K04066 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,ResIII k141_27590_1 911045.PSE_3389 1.85e-08 60.8 COG0658@1|root,COG0658@2|Bacteria,1MUKF@1224|Proteobacteria,2TRD5@28211|Alphaproteobacteria 28211|Alphaproteobacteria S membrane metal-binding protein - - - ko:K02238 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - Competence,DUF4131 k141_22972_1 218284.CCDN010000001_gene508 3.13e-127 392.0 COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,4H9T3@91061|Bacilli,1ZCIC@1386|Bacillus 91061|Bacilli L DNA polymerase dnaE - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon k141_9839_1 1453501.JELR01000002_gene476 1.31e-107 333.0 COG3525@1|root,COG3525@2|Bacteria,1MVDE@1224|Proteobacteria,1RMNI@1236|Gammaproteobacteria,465UJ@72275|Alteromonadaceae 1236|Gammaproteobacteria G Glycosyl hydrolase family 20, domain 2 nahA - 3.2.1.52 ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 M00079 R00022,R06004,R11316 RC00049 ko00000,ko00001,ko00002,ko01000,ko03110 - GH20 - CHB_HEX_C_1,Glyco_hydro_20,Glyco_hydro_20b k141_33614_2 1453501.JELR01000002_gene708 4.83e-52 166.0 COG4519@1|root,COG4519@2|Bacteria,1N38K@1224|Proteobacteria,1SAIP@1236|Gammaproteobacteria,46DJX@72275|Alteromonadaceae 1236|Gammaproteobacteria S Winged helix-turn helix - - - - - - - - - - - - HTH_43 k141_24100_4 1116375.VEJY3_20021 9.79e-202 560.0 COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,1RPT8@1236|Gammaproteobacteria,1XTZM@135623|Vibrionales 135623|Vibrionales K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_24100_5 1116375.VEJY3_20026 8.12e-304 833.0 COG0517@1|root,COG2116@1|root,COG0517@2|Bacteria,COG2116@2|Bacteria,1MU0W@1224|Proteobacteria,1RQ6K@1236|Gammaproteobacteria,1XUCS@135623|Vibrionales 135623|Vibrionales P COG2116 Formate nitrite family of transporters VVA0737 - - ko:K06212 - - - - ko00000,ko02000 1.A.16.1.1,1.A.16.1.3 - - CBS,Form_Nir_trans k141_24100_6 1116375.VEJY3_20031 1.43e-58 184.0 COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,1S24R@1236|Gammaproteobacteria,1XUIB@135623|Vibrionales 135623|Vibrionales S UPF0312 protein - - - - - - - - - - - - YceI k141_33641_2 218284.CCDN010000001_gene1015 2.01e-113 331.0 COG0300@1|root,COG0300@2|Bacteria,1TSJ3@1239|Firmicutes,4HDU5@91061|Bacilli,1ZBRZ@1386|Bacillus 91061|Bacilli S Belongs to the short-chain dehydrogenases reductases (SDR) family yqjQ - - ko:K07124 - - - - ko00000 - - - adh_short k141_11061_1 218284.CCDN010000008_gene4151 6.09e-82 251.0 COG0803@1|root,COG0803@2|Bacteria,1TPG7@1239|Firmicutes,4H9UN@91061|Bacilli,1ZC2Z@1386|Bacillus 91061|Bacilli P Belongs to the bacterial solute-binding protein 9 family adcA - - ko:K09815,ko:K09818 ko02010,map02010 M00242,M00243 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 - - ZnuA k141_8700_1 1165096.ARWF01000001_gene2359 1.31e-121 361.0 COG2079@1|root,COG2079@2|Bacteria,1MUIG@1224|Proteobacteria,2VH7T@28216|Betaproteobacteria,2KMJJ@206350|Nitrosomonadales 206350|Nitrosomonadales S MmgE/PrpD family - - 4.2.1.79 ko:K01720 ko00640,map00640 - R04424 RC01152 ko00000,ko00001,ko01000 - - - MmgE_PrpD k141_13511_1 218284.CCDN010000005_gene3247 2.81e-189 539.0 COG0366@1|root,COG0366@2|Bacteria,1TNZ0@1239|Firmicutes,4HB67@91061|Bacilli,1ZAZP@1386|Bacillus 91061|Bacilli G Alpha amylase, N-terminal ig-like domain nplT - 3.2.1.133,3.2.1.135,3.2.1.54 ko:K01208 ko00500,ko01100,map00500,map01100 - R02112,R03122,R11262 - ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,Alpha-amylase_N,Malt_amylase_C k141_25324_1 218284.CCDN010000001_gene1272 2.6e-128 370.0 COG0253@1|root,COG0253@2|Bacteria,1TPMN@1239|Firmicutes,4HBH4@91061|Bacilli,1ZD98@1386|Bacillus 91061|Bacilli E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan dapF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 - - - DAP_epimerase k141_22998_1 1042377.AFPJ01000052_gene1585 6.15e-113 350.0 COG1629@1|root,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria,4652I@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec k141_21762_1 1123366.TH3_04609 2.7e-50 180.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria,2JPRP@204441|Rhodospirillales 204441|Rhodospirillales V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K18138 ko01501,ko01503,map01501,map01503 M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2 - - ACR_tran k141_24101_1 42565.FP66_03045 1.1e-35 126.0 COG1011@1|root,COG1011@2|Bacteria,1MVWN@1224|Proteobacteria,1RR0H@1236|Gammaproteobacteria,1XJJP@135619|Oceanospirillales 135619|Oceanospirillales S Haloacid dehalogenase - - 3.8.1.2 ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 - R05287 RC00697 ko00000,ko00001,ko01000 - - - HAD_2 k141_24101_2 42565.FP66_03040 3.25e-31 110.0 COG5660@1|root,COG5660@2|Bacteria,1NH4R@1224|Proteobacteria,1SH4J@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Transmembrane anti-sigma factor - - - - - - - - - - - - zf-HC2 k141_24101_3 42565.FP66_03035 1.92e-36 127.0 COG1595@1|root,COG1595@2|Bacteria,1RHKM@1224|Proteobacteria,1S48U@1236|Gammaproteobacteria,1XK4H@135619|Oceanospirillales 135619|Oceanospirillales K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_31266_1 42565.FP66_05635 9.57e-92 281.0 COG1012@1|root,COG1012@2|Bacteria,1MUHV@1224|Proteobacteria,1RNFN@1236|Gammaproteobacteria,1XIE7@135619|Oceanospirillales 135619|Oceanospirillales C methylmalonate-semialdehyde dehydrogenase - - 1.2.1.18,1.2.1.27 ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 M00013 R00705,R00706,R00922,R00935 RC00004,RC02723,RC02817 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_8701_1 1294265.JCM21738_3339 9.61e-37 125.0 COG4129@1|root,COG4129@2|Bacteria 2|Bacteria - - ygaE - - - - - - - - - - - ArAE_1 k141_32349_2 379066.GAU_3915 4.34e-40 138.0 COG1595@1|root,COG1595@2|Bacteria,1ZT2V@142182|Gemmatimonadetes 142182|Gemmatimonadetes K ECF sigma factor - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_456_1 218284.CCDN010000002_gene2208 4.73e-114 346.0 COG0840@1|root,COG0840@2|Bacteria,1UVY9@1239|Firmicutes,4HB1T@91061|Bacilli,1ZD8I@1386|Bacillus 91061|Bacilli NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). yvaQ - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal k141_28909_1 1279017.AQYJ01000019_gene1471 6.61e-136 385.0 COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,1RQ38@1236|Gammaproteobacteria,464TW@72275|Alteromonadaceae 1236|Gammaproteobacteria J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit rpsD GO:0000028,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006417,GO:0006446,GO:0006450,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0015935,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030371,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031554,GO:0031564,GO:0032268,GO:0032269,GO:0032270,GO:0032991,GO:0034248,GO:0034249,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043244,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0045727,GO:0045903,GO:0045947,GO:0048027,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0065008,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990145,GO:1990904,GO:2000112,GO:2000113,GO:2001141 - ko:K02986 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S4,S4 k141_28909_2 1453501.JELR01000005_gene1743 3.03e-86 254.0 COG0100@1|root,COG0100@2|Bacteria,1RD0A@1224|Proteobacteria,1S3Q2@1236|Gammaproteobacteria,466ID@72275|Alteromonadaceae 1236|Gammaproteobacteria J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome rpsK GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02948 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S11 k141_9878_1 1280001.BAOA01000123_gene1037 5.48e-165 471.0 COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,1RNN1@1236|Gammaproteobacteria,1XWDE@135623|Vibrionales 135623|Vibrionales S AI-2E family transporter - - - - - - - - - - - - AI-2E_transport k141_13512_1 441769.ABFU01000019_gene3449 1.05e-96 293.0 COG0477@1|root,COG2814@2|Bacteria,1TS6K@1239|Firmicutes,4HB1V@91061|Bacilli,1ZB90@1386|Bacillus 91061|Bacilli EGP COG0477 Permeases of the major facilitator superfamily - - - ko:K08153 - M00717 - - ko00000,ko00002,ko02000 2.A.1.2.8 - - MFS_1,Sugar_tr k141_6497_1 1121936.AUHI01000018_gene692 3.97e-14 67.4 COG2163@1|root,COG2163@2|Bacteria,1VEPA@1239|Firmicutes,4HJQF@91061|Bacilli 91061|Bacilli J COG2163 Ribosomal protein L14E L6E L27E - - - - - - - - - - - - KOW k141_6497_3 999415.HMPREF9943_00576 2.39e-15 68.2 COG0257@1|root,COG0257@2|Bacteria,1VK4F@1239|Firmicutes,3VSAE@526524|Erysipelotrichia 526524|Erysipelotrichia J Belongs to the bacterial ribosomal protein bL36 family rpmJ - - - - - - - - - - - Ribosomal_L36 k141_10108_1 1453501.JELR01000002_gene341 5.03e-10 61.6 COG2885@1|root,COG2885@2|Bacteria,1QW22@1224|Proteobacteria,1T4AK@1236|Gammaproteobacteria,46ACU@72275|Alteromonadaceae 1236|Gammaproteobacteria M OmpA family - - - - - - - - - - - - DUF11,OmpA k141_10108_2 1453501.JELR01000002_gene342 5.86e-90 294.0 COG1361@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4932@2|Bacteria,1R5G4@1224|Proteobacteria,1SEWA@1236|Gammaproteobacteria,469S7@72275|Alteromonadaceae 1236|Gammaproteobacteria M Domain of unknown function DUF11 - - - - - - - - - - - - DUF11,SdrD_B k141_19544_1 218284.CCDN010000005_gene3290 7.18e-116 343.0 COG4469@1|root,COG4469@2|Bacteria,1TRGD@1239|Firmicutes,4HFP5@91061|Bacilli,1ZCFD@1386|Bacillus 91061|Bacilli S Competence protein coiA - - ko:K06198 - - - - ko00000 - - - CoiA k141_4138_1 42565.FP66_07765 8.79e-107 318.0 COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,1RNS4@1236|Gammaproteobacteria,1XHUY@135619|Oceanospirillales 135619|Oceanospirillales F Belongs to the GARS family purD - 6.3.4.13 ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144 RC00090,RC00166 ko00000,ko00001,ko00002,ko01000 - - - GARS_A,GARS_C,GARS_N k141_37272_2 1116375.VEJY3_23556 2.39e-205 570.0 COG0583@1|root,COG0583@2|Bacteria,1N4BZ@1224|Proteobacteria,1RRCD@1236|Gammaproteobacteria,1XTHR@135623|Vibrionales 135623|Vibrionales K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_37272_3 223926.28809921 4.09e-122 352.0 28TMI@1|root,2ZFV4@2|Bacteria,1R9YK@1224|Proteobacteria,1S221@1236|Gammaproteobacteria,1XUFY@135623|Vibrionales 135623|Vibrionales S Spondin_N - - - - - - - - - - - - Spond_N k141_21901_1 218284.CCDN010000002_gene2063 8.65e-54 183.0 COG4129@1|root,COG4129@2|Bacteria,1UY2G@1239|Firmicutes,4HAWK@91061|Bacilli,1ZBAR@1386|Bacillus 91061|Bacilli S Aromatic acid exporter family member 1 - - - - - - - - - - - - ArAE_1 k141_650_1 1117647.M5M_10260 3.92e-77 255.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MUWN@1224|Proteobacteria,1RN1E@1236|Gammaproteobacteria,1J635@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec k141_35001_1 218284.CCDN010000001_gene137 6.95e-114 338.0 COG1875@1|root,COG1875@2|Bacteria,1UHTD@1239|Firmicutes,4HA4V@91061|Bacilli,1ZDIF@1386|Bacillus 91061|Bacilli T ATPase related to phosphate starvation-inducible protein PhoH ylaK - - ko:K07175 - - - - ko00000 - - - PIN_4,PhoH k141_13724_1 1279017.AQYJ01000029_gene3881 1.22e-41 151.0 COG1538@1|root,COG1538@2|Bacteria,1NEZC@1224|Proteobacteria,1RPC5@1236|Gammaproteobacteria,46CG5@72275|Alteromonadaceae 1236|Gammaproteobacteria MU Outer membrane efflux protein - - - ko:K15725 - - - - ko00000,ko02000 1.B.17.2.2 - - OEP k141_5329_1 1279017.AQYJ01000026_gene246 9.23e-89 272.0 COG2050@1|root,COG2050@2|Bacteria,1RF3N@1224|Proteobacteria,1S82J@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q Thioesterase - - - - - - - - - - - - 4HBT k141_5329_2 7029.ACYPI087816-PA 6.5e-17 79.3 COG1502@1|root,2RKKV@2759|Eukaryota,3AHCQ@33154|Opisthokonta,3BZ22@33208|Metazoa,3DDA8@33213|Bilateria,427YH@6656|Arthropoda,3SR5V@50557|Insecta 33208|Metazoa I Phospholipase D Active site motif - - - - - - - - - - - - PLDc_2 k141_5329_3 349521.HCH_02023 2.61e-50 164.0 COG3011@1|root,COG3011@2|Bacteria,1RG68@1224|Proteobacteria 1224|Proteobacteria S thiol-disulphide oxidoreductase DCC - - - - - - - - - - - - DUF393 k141_5329_4 333138.LQ50_11335 4.62e-57 184.0 COG0110@1|root,COG0110@2|Bacteria,1TQEX@1239|Firmicutes,4HAJ0@91061|Bacilli,1ZDPK@1386|Bacillus 91061|Bacilli S COG0110 Acetyltransferase (isoleucine patch superfamily) maa - 2.3.1.79 ko:K00661 - - - - ko00000,ko01000 - - - CM_2,Hexapep,Hexapep_2,Mac k141_24232_1 1042377.AFPJ01000044_gene641 1.67e-108 326.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,465V5@72275|Alteromonadaceae 1236|Gammaproteobacteria C Aldehyde dehydrogenase family aldH - 1.2.1.54,1.2.1.99 ko:K09472,ko:K12254 ko00330,ko01100,map00330,map01100 M00136 R02549,R03177,R07417,R07418 RC00080 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_5278 Aldedh k141_24232_2 1279017.AQYJ01000028_gene2115 4.34e-38 130.0 2E35S@1|root,32Y5P@2|Bacteria,1N6WS@1224|Proteobacteria,1SD5T@1236|Gammaproteobacteria,468S2@72275|Alteromonadaceae 1236|Gammaproteobacteria S Putative prokaryotic signal transducing protein - - - - - - - - - - - - DUF2007 k141_30107_2 1042377.AFPJ01000007_gene1875 4.46e-73 222.0 COG1246@1|root,COG1246@2|Bacteria,1QU0G@1224|Proteobacteria,1TAYS@1236|Gammaproteobacteria,46BU6@72275|Alteromonadaceae 1236|Gammaproteobacteria E Acetyltransferase (GNAT) family - - - - - - - - - - - - Acetyltransf_7 k141_30107_3 1121374.KB891589_gene105 3.35e-83 252.0 COG3148@1|root,COG3148@2|Bacteria,1MZCN@1224|Proteobacteria,1S977@1236|Gammaproteobacteria 1236|Gammaproteobacteria S PFAM DTW domain containing protein - - - ko:K05812 - - - - ko00000 - - - DTW k141_4139_1 1116375.VEJY3_21846 2.76e-77 234.0 COG0546@1|root,COG0546@2|Bacteria,1RHAA@1224|Proteobacteria,1S7HQ@1236|Gammaproteobacteria,1XWVY@135623|Vibrionales 135623|Vibrionales S phosphatases - - - - - - - - - - - - HAD_2 k141_25545_1 1279017.AQYJ01000023_gene3250 1.4e-201 570.0 COG1012@1|root,COG1012@2|Bacteria,1MVGW@1224|Proteobacteria,1RN53@1236|Gammaproteobacteria,4656Y@72275|Alteromonadaceae 1236|Gammaproteobacteria C belongs to the aldehyde dehydrogenase family ywdH - 1.2.1.3 ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_25545_2 1279017.AQYJ01000023_gene3249 1.73e-134 389.0 COG3725@1|root,COG3725@2|Bacteria,1RH1N@1224|Proteobacteria,1S6GK@1236|Gammaproteobacteria,467BI@72275|Alteromonadaceae 1236|Gammaproteobacteria V Membrane protein required for beta-lactamase induction ampE - - ko:K03807 - - - - ko00000 - - - AmpE k141_25545_4 1453501.JELR01000006_gene13 2.48e-285 816.0 COG4223@1|root,COG4223@2|Bacteria,1N10X@1224|Proteobacteria,1RYCQ@1236|Gammaproteobacteria,46D2D@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF1631) - - - - - - - - - - - - DUF1631 k141_24233_1 1042377.AFPJ01000036_gene1134 1.73e-103 324.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MV8W@1224|Proteobacteria,1RMQA@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Outer membrane receptor proteins mostly Fe transport - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_13725_1 1279017.AQYJ01000022_gene2725 1.13e-100 294.0 COG1595@1|root,COG1595@2|Bacteria,1N6SV@1224|Proteobacteria,1SYWE@1236|Gammaproteobacteria,468CK@72275|Alteromonadaceae 1236|Gammaproteobacteria K Sigma-70, region 4 - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_37273_1 218284.CCDN010000005_gene3264 9.38e-66 200.0 COG2151@1|root,COG2151@2|Bacteria,1V9YV@1239|Firmicutes,4HKC6@91061|Bacilli,1ZH2A@1386|Bacillus 91061|Bacilli S metal-sulfur cluster biosynthetic enzyme yitW - - - - - - - - - - - FeS_assembly_P k141_10110_2 218284.CCDN010000005_gene3411 1.1e-49 158.0 2CGTU@1|root,32Z9H@2|Bacteria,1VG36@1239|Firmicutes,4HNI4@91061|Bacilli,1ZI34@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3055) - - - - - - - - - - - - DUF3055 k141_10110_3 1444310.JANV01000097_gene2198 2.73e-32 116.0 COG2445@1|root,COG2445@2|Bacteria,1V6HM@1239|Firmicutes,4HITV@91061|Bacilli,1ZGY2@1386|Bacillus 91061|Bacilli S Protein of unknown function DUF86 yutE - - - - - - - - - - - DUF86 k141_11271_1 1042377.AFPJ01000036_gene1132 1.91e-70 236.0 COG0308@1|root,COG0308@2|Bacteria,1MUV3@1224|Proteobacteria,1RS0E@1236|Gammaproteobacteria,4666I@72275|Alteromonadaceae 1236|Gammaproteobacteria E Peptidase family M1 domain - - - - - - - - - - - - Peptidase_M1 k141_29003_1 1149133.ppKF707_5764 2.43e-18 86.7 28IAG@1|root,2Z8D2@2|Bacteria,1P5EH@1224|Proteobacteria,1RYCA@1236|Gammaproteobacteria,1YCYG@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S Domain of unknown function (DUF4129) - - - - - - - - - - - - DUF4129 k141_29003_2 1279017.AQYJ01000028_gene2063 9.38e-108 319.0 COG1300@1|root,COG1300@2|Bacteria,1Q1GN@1224|Proteobacteria,1RR61@1236|Gammaproteobacteria,466VE@72275|Alteromonadaceae 1236|Gammaproteobacteria S Stage II sporulation protein M - - - - - - - - - - - - SpoIIM k141_35004_1 42565.FP66_03470 3.4e-90 283.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPES@1236|Gammaproteobacteria,1XH5X@135619|Oceanospirillales 135619|Oceanospirillales S ABC transporter ATP-binding protein - - - ko:K06158 - - - - ko00000,ko03012 - - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn k141_15926_1 1453501.JELR01000001_gene2023 8.33e-122 355.0 COG1752@1|root,COG1752@2|Bacteria,1MU6Z@1224|Proteobacteria,1RPW6@1236|Gammaproteobacteria,4669M@72275|Alteromonadaceae 1236|Gammaproteobacteria S Esterase of the alpha-beta hydrolase superfamily - - - - - - - - - - - - Patatin k141_13726_1 218284.CCDN010000002_gene2164 9.79e-100 301.0 COG2244@1|root,COG2244@2|Bacteria,1VRYZ@1239|Firmicutes,4HV8Z@91061|Bacilli,1ZCGG@1386|Bacillus 91061|Bacilli S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid ykvU - - - - - - - - - - - MatE,Polysacc_synt,Polysacc_synt_C k141_2831_1 1453501.JELR01000001_gene2919 4e-131 377.0 COG0730@1|root,COG0730@2|Bacteria,1RAG9@1224|Proteobacteria,1S2RX@1236|Gammaproteobacteria,466JN@72275|Alteromonadaceae 1236|Gammaproteobacteria S membrane transporter protein - - - - - - - - - - - - TauE k141_20688_1 1487953.JMKF01000018_gene2290 4.65e-57 201.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1G0GP@1117|Cyanobacteria,1H9GG@1150|Oscillatoriales 1117|Cyanobacteria G Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate ppsA - 2.7.9.2 ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 M00173,M00374 R00199 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - PEP-utilizers,PEP-utilizers_C,PPDK_N k141_1641_2 218284.CCDN010000006_gene3532 3.64e-64 196.0 COG0526@1|root,COG0526@2|Bacteria,1VA84@1239|Firmicutes,4HKCD@91061|Bacilli,1ZHXM@1386|Bacillus 91061|Bacilli CO Thioredoxin ydbP GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - - - - - - - - - - Thioredoxin k141_29017_2 1123405.AUMM01000001_gene91 1.43e-19 89.7 COG0758@1|root,COG0758@2|Bacteria,1TPP7@1239|Firmicutes,4HGWM@91061|Bacilli,26NS7@186821|Sporolactobacillaceae 91061|Bacilli LU DNA recombination-mediator protein A dprA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0007154,GO:0008150,GO:0009292,GO:0009294,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0044424,GO:0044464,GO:0044764,GO:0050896,GO:0051704,GO:0051716,GO:0071496 - ko:K04096 - - - - ko00000 - - - DNA_processg_A k141_13753_1 1294265.JCM21738_1327 7.3e-46 152.0 COG5018@1|root,COG5018@2|Bacteria,1TT8A@1239|Firmicutes,4HFEZ@91061|Bacilli,1ZBWS@1386|Bacillus 91061|Bacilli L Inhibitor of the KinA pathway kapD - - ko:K06348 - - - - ko00000 - - - RNase_T k141_11290_1 935836.JAEL01000017_gene810 4.3e-76 237.0 2EDMZ@1|root,337HS@2|Bacteria,1VPSQ@1239|Firmicutes,4HRHN@91061|Bacilli,1ZB19@1386|Bacillus 91061|Bacilli S YtkA-like - - - - - - - - - - - - YtkA k141_4153_2 1453501.JELR01000001_gene2061 1.77e-58 191.0 COG0472@1|root,COG0472@2|Bacteria,1MWYW@1224|Proteobacteria,1RNAP@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP- C55) wbpL - - ko:K13007 - - - - ko00000,ko01000,ko01003,ko01005 - - - Glycos_transf_4 k141_18441_1 1279017.AQYJ01000025_gene567 7.87e-190 556.0 COG1629@1|root,COG4771@2|Bacteria,1N6JG@1224|Proteobacteria,1RP10@1236|Gammaproteobacteria,465FE@72275|Alteromonadaceae 1236|Gammaproteobacteria P Carboxypeptidase regulatory-like domain - - - - - - - - - - - - CarboxypepD_reg,Plug,TonB_dep_Rec k141_35013_1 1116375.VEJY3_06035 0.0 999.0 COG4988@1|root,COG4988@2|Bacteria,1QU1N@1224|Proteobacteria,1RNPI@1236|Gammaproteobacteria,1XUSA@135623|Vibrionales 135623|Vibrionales CO COG4988 ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components cydD - - ko:K16013 ko02010,map02010 - - - ko00000,ko00001,ko02000 3.A.1.129 - - ABC_membrane,ABC_tran k141_35013_2 1280001.BAOA01000019_gene426 2.11e-223 616.0 COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,1RMEX@1236|Gammaproteobacteria,1XSDE@135623|Vibrionales 135623|Vibrionales C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family trxB GO:0003674,GO:0003824,GO:0004791,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0042221,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Pyr_redox_2 k141_35013_3 223926.28806240 6.84e-147 414.0 COG4340@1|root,COG4340@2|Bacteria,1R9YQ@1224|Proteobacteria,1RN37@1236|Gammaproteobacteria,1XTRV@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria - - - - - - - - - - - - 2OG-Fe_Oxy_2 k141_35013_4 1116375.VEJY3_06050 1.78e-282 773.0 COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,1RNIY@1236|Gammaproteobacteria,1XSAY@135623|Vibrionales 135623|Vibrionales E COG0520 Selenocysteine lyase - - - - - - - - - - - - Aminotran_5 k141_35013_5 1116375.VEJY3_06055 1.52e-198 550.0 2BVTQ@1|root,2Z7J9@2|Bacteria,1P01Z@1224|Proteobacteria,1RNNB@1236|Gammaproteobacteria,1XT57@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF2797) LA2027 - - - - - - - - - - - DUF2797 k141_35013_6 223926.28806243 7.81e-255 706.0 COG2199@1|root,COG3706@2|Bacteria,1RD8D@1224|Proteobacteria,1SYKF@1236|Gammaproteobacteria,1XTPB@135623|Vibrionales 135623|Vibrionales T COG2199 FOG GGDEF domain - - - - - - - - - - - - CIA30,GGDEF k141_35013_7 1116375.VEJY3_06060 3.05e-299 820.0 COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,1RPU5@1236|Gammaproteobacteria,1XVCC@135623|Vibrionales 135623|Vibrionales P COG0471 Di- and tricarboxylate transporters - - - ko:K14445 - - - - ko00000,ko02000 2.A.47.1 - - Na_sulph_symp k141_14706_1 223926.28809217 2.73e-18 76.6 COG3140@1|root,COG3140@2|Bacteria,1N89H@1224|Proteobacteria,1SCHP@1236|Gammaproteobacteria,1XZEF@135623|Vibrionales 135623|Vibrionales S Belongs to the UPF0181 family - - - ko:K09917 - - - - ko00000 - - - UPF0181 k141_14706_2 223926.28809218 3.65e-194 545.0 28IW1@1|root,2Z8UB@2|Bacteria,1N1QM@1224|Proteobacteria,1RR0J@1236|Gammaproteobacteria,1XSR0@135623|Vibrionales 135623|Vibrionales S F plasmid transfer operon, TraF, protein - - - - - - - - - - - - TraF_2 k141_659_1 1279017.AQYJ01000019_gene1521 7.54e-06 47.4 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,464CD@72275|Alteromonadaceae 1236|Gammaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family mtrD_1 - - ko:K18138,ko:K18307 ko01501,ko01503,ko02024,map01501,map01503,map02024 M00644,M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2,2.A.6.2.20,2.A.6.2.32 - - ACR_tran k141_659_2 592029.DDD_0473 5.03e-50 167.0 COG2335@1|root,COG2335@2|Bacteria,4NMPI@976|Bacteroidetes,1I1DK@117743|Flavobacteriia 976|Bacteroidetes M COG2335 Secreted and surface protein containing fasciclin-like repeats - - - - - - - - - - - - Fasciclin k141_659_3 1042377.AFPJ01000029_gene526 2.85e-32 120.0 2DR2Y@1|root,339YA@2|Bacteria,1NHB7@1224|Proteobacteria,1SH0X@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF4124) - - - - - - - - - - - - DUF4124 k141_659_4 1453501.JELR01000005_gene1793 0.0 1074.0 COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,1RMQQ@1236|Gammaproteobacteria,464ZP@72275|Alteromonadaceae 1236|Gammaproteobacteria H COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase ilvI GO:0000287,GO:0003674,GO:0003824,GO:0003984,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0019842,GO:0030976,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901681 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_1907,iB21_1397.B21_00078,iBWG_1329.BWG_0073,iECBD_1354.ECBD_3539,iECB_1328.ECB_00079,iECD_1391.ECD_00079,iUTI89_1310.UTI89_C0085,iYL1228.KPN_00082 TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N k141_659_5 1279017.AQYJ01000019_gene1527 1.3e-97 285.0 COG0440@1|root,COG0440@2|Bacteria,1RAGN@1224|Proteobacteria,1S20I@1236|Gammaproteobacteria,466IV@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0440 Acetolactate synthase, small (regulatory) subunit ilvH GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 ko:K01653 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_1906,iECNA114_1301.ECNA114_0072,iEcSMS35_1347.EcSMS35_0084,iG2583_1286.G2583_0082,iSFxv_1172.SFxv_0077,iUTI89_1310.UTI89_C0086 ACT,ACT_5,ALS_ss_C k141_659_6 1453501.JELR01000005_gene1795 2.29e-229 633.0 COG0059@1|root,COG0059@2|Bacteria,1MV7M@1224|Proteobacteria,1RNA8@1236|Gammaproteobacteria,464ET@72275|Alteromonadaceae 1236|Gammaproteobacteria EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate ilvC GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004455,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0022607,GO:0036094,GO:0042802,GO:0043167,GO:0043169,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.86 ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R03051,R04439,R04440,R05068,R05069,R05071 RC00726,RC00836,RC00837,RC01726 ko00000,ko00001,ko00002,ko01000 - - iEC042_1314.EC042_4152,iECABU_c1320.ECABU_c42560,iECED1_1282.ECED1_4460,iECO103_1326.ECO103_4390,iECO111_1330.ECO111_4600,iECO26_1355.ECO26_4812,iECP_1309.ECP_3967,iECSE_1348.ECSE_4057,iECUMN_1333.ECUMN_4300,iEcE24377_1341.EcE24377A_4285,iEcSMS35_1347.EcSMS35_4140,iJN746.PP_4678,iLF82_1304.LF82_1103 IlvC,IlvN k141_659_7 1453501.JELR01000005_gene1796 3.86e-151 433.0 COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,1RPBB@1236|Gammaproteobacteria,4645F@72275|Alteromonadaceae 1236|Gammaproteobacteria I Belongs to the CDP-alcohol phosphatidyltransferase class-I family pssA - 2.7.8.8 ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 M00093 R01800 RC00002,RC00017,RC02795 ko00000,ko00001,ko00002,ko01000 - - - CDP-OH_P_transf k141_24256_3 218284.CCDN010000008_gene4262 2.97e-39 137.0 COG1387@1|root,COG1387@2|Bacteria,1TQQX@1239|Firmicutes,4H9P1@91061|Bacilli,1ZCA3@1386|Bacillus 91061|Bacilli E COG1387 Histidinol phosphatase and related hydrolases of the PHP family hisK GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.15 ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R03013 RC00017 ko00000,ko00001,ko00002,ko01000 - - - PHP,PHP_C k141_20690_1 1078085.HMPREF1210_02818 4.19e-45 148.0 2E6WB@1|root,331FV@2|Bacteria,1VF7B@1239|Firmicutes,4HNST@91061|Bacilli 91061|Bacilli S Membrane - - - - - - - - - - - - - k141_25580_2 574375.BAGA_18565 1.71e-20 85.9 COG3575@1|root,COG3575@2|Bacteria,1V1YD@1239|Firmicutes,4HGK6@91061|Bacilli,1ZFNC@1386|Bacillus 91061|Bacilli S protein conserved in bacteria - - - ko:K09962 - - - - ko00000 - - - NTP_transf_6 k141_27710_1 223926.28808978 9.86e-94 293.0 COG0784@1|root,COG0784@2|Bacteria,1QUZH@1224|Proteobacteria,1T2JI@1236|Gammaproteobacteria,1XT5E@135623|Vibrionales 135623|Vibrionales T cheY-homologous receiver domain - - - - - - - - - - - - Response_reg,TPR_19 k141_27710_3 1280001.BAOA01000213_gene13 2.68e-144 410.0 COG0730@1|root,COG0730@2|Bacteria,1N4D8@1224|Proteobacteria,1SB2U@1236|Gammaproteobacteria,1XSEW@135623|Vibrionales 135623|Vibrionales S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE k141_27710_4 223926.28808987 1.43e-70 214.0 COG3788@1|root,COG3788@2|Bacteria,1RDHP@1224|Proteobacteria,1S3PN@1236|Gammaproteobacteria,1XXEP@135623|Vibrionales 135623|Vibrionales S relative of glutathione S-transferase, MAPEG superfamily - - - ko:K07136 - - - - ko00000 - - - MAPEG k141_27710_5 1116375.VEJY3_19186 3.82e-185 518.0 COG0697@1|root,COG0697@2|Bacteria,1MZXM@1224|Proteobacteria,1RRID@1236|Gammaproteobacteria,1XTUE@135623|Vibrionales 135623|Vibrionales EG of the drug metabolite transporter (DMT) superfamily - - - - - - - - - - - - EamA k141_35014_1 498848.TaqDRAFT_3427 5.13e-06 48.1 COG1622@1|root,COG1622@2|Bacteria,1WJJY@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus C cytochrome c oxidase subunit II - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.9.3.1 ko:K02275 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.4,3.D.4.6 - - COX2,COX2-transmemb k141_35014_2 309801.trd_A0394 5.24e-25 105.0 COG0843@1|root,COG0843@2|Bacteria,2G628@200795|Chloroflexi,27YW1@189775|Thermomicrobia 189775|Thermomicrobia C Cytochrome C and Quinol oxidase polypeptide I - - 1.9.3.1 ko:K02274 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6 - - COX1 k141_4154_1 1189619.pgond44_10819 4.16e-27 105.0 COG1970@1|root,COG1970@2|Bacteria,4NQ49@976|Bacteroidetes,1I2CT@117743|Flavobacteriia,4C4EN@83612|Psychroflexus 976|Bacteroidetes M Large-conductance mechanosensitive channel, MscL mscL GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - ko:K03282 - - - - ko00000,ko02000 1.A.22.1 - - MscL k141_11291_2 1178540.BA70_18625 9.07e-90 274.0 COG3935@1|root,COG3935@2|Bacteria,1TSHD@1239|Firmicutes,4HIGY@91061|Bacilli,1ZCUE@1386|Bacillus 91061|Bacilli L Conserved phage C-terminus (Phg_2220_C) - - - - - - - - - - - - Phage_rep_org_N,Phg_2220_C k141_2848_1 493475.GARC_2325 1.03e-84 260.0 COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,1RMJJ@1236|Gammaproteobacteria,465VY@72275|Alteromonadaceae 1236|Gammaproteobacteria KT Response regulator of the LytR AlgR family - - - ko:K02477 - - - - ko00000,ko02022 - - - LytTR,Response_reg k141_2848_2 314287.GB2207_03389 7.75e-45 160.0 COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,1RQDA@1236|Gammaproteobacteria 1236|Gammaproteobacteria T signal transduction protein with a C-terminal ATPase domain yesM - 2.7.13.3 ko:K08082 ko02020,map02020 M00493 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,His_kinase k141_10135_1 218284.CCDN010000008_gene4265 1.33e-133 389.0 COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,4HAEE@91061|Bacilli,1ZBHY@1386|Bacillus 91061|Bacilli E Cysteine desulfurase iscS2 - 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - - Aminotran_5 k141_10135_2 218284.CCDN010000008_gene4264 6.36e-266 735.0 COG1114@1|root,COG1114@2|Bacteria,1TQIS@1239|Firmicutes,4HAKA@91061|Bacilli,1ZAST@1386|Bacillus 91061|Bacilli E Component of the transport system for branched-chain amino acids braB GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015175,GO:0015179,GO:0015188,GO:0015190,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0034220,GO:0042221,GO:0042493,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903785,GO:1903825,GO:1905039 - ko:K03311 - - - - ko00000 2.A.26 - - Branch_AA_trans k141_660_1 477974.Daud_1178 4.6e-12 68.6 COG0539@1|root,COG0761@1|root,COG0539@2|Bacteria,COG0761@2|Bacteria,1TQ9N@1239|Firmicutes,247UK@186801|Clostridia,26081@186807|Peptococcaceae 186801|Clostridia IJM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis ispH - 1.17.7.4 ko:K02945,ko:K03527 ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010 M00096,M00178 R05884,R08210 RC01137,RC01487 br01610,ko00000,ko00001,ko00002,ko01000,ko03011 - - - LYTB,S1 k141_7591_1 1161401.ASJA01000005_gene2417 3.67e-168 502.0 COG1629@1|root,COG4771@2|Bacteria,1MVFB@1224|Proteobacteria,2U2UJ@28211|Alphaproteobacteria,43WVS@69657|Hyphomonadaceae 28211|Alphaproteobacteria P receptor - - - - - - - - - - - - Plug,TonB_dep_Rec k141_20692_1 999141.GME_00395 7.94e-99 308.0 COG1765@1|root,COG1944@1|root,COG1765@2|Bacteria,COG1944@2|Bacteria,1MV7K@1224|Proteobacteria,1RN47@1236|Gammaproteobacteria,1XHD4@135619|Oceanospirillales 135619|Oceanospirillales O redox protein, regulator of disulfide bond formation - - - ko:K09136 - - - - ko00000,ko03009 - - - OsmC,YcaO k141_13755_2 1265503.KB905165_gene1050 1.97e-46 154.0 2DMKI@1|root,32S70@2|Bacteria,1N1FV@1224|Proteobacteria,1S778@1236|Gammaproteobacteria 1236|Gammaproteobacteria S SpoIIAA-like VVA0543 - - - - - - - - - - - SpoIIAA-like k141_26898_1 1283337.B0ZSI4_BPHA1 1.34e-108 348.0 4QAY9@10239|Viruses,4QUV8@35237|dsDNA viruses no RNA stage,4QPFD@28883|Caudovirales,4QIII@10662|Myoviridae 10662|Myoviridae S hydrolase activity, acting on acid anhydrides - - - - - - - - - - - - - k141_1642_1 1453501.JELR01000002_gene166 1.79e-172 498.0 COG3608@1|root,COG3608@2|Bacteria,1MUAA@1224|Proteobacteria,1RNQQ@1236|Gammaproteobacteria,464NX@72275|Alteromonadaceae 1236|Gammaproteobacteria S Succinylglutamate desuccinylase / Aspartoacylase family - - - ko:K06987 - - - - ko00000 - - - AstE_AspA k141_8912_2 1453501.JELR01000001_gene2993 1.32e-62 195.0 2B2JB@1|root,32XJW@2|Bacteria,1MZQH@1224|Proteobacteria,1SB5E@1236|Gammaproteobacteria,46DN6@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF2750) - - - - - - - - - - - - DUF2750 k141_8912_3 1042377.AFPJ01000013_gene1739 1.51e-67 211.0 COG0791@1|root,COG0791@2|Bacteria,1N0EE@1224|Proteobacteria,1RR2X@1236|Gammaproteobacteria,4683S@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0791 Cell wall-associated hydrolases (invasion-associated proteins) nlpC - 3.4.17.13 ko:K13694,ko:K13695 - - - - ko00000,ko01000,ko01002,ko01011 - - - NLPC_P60 k141_8912_4 371731.Rsw2DRAFT_2796 1.53e-28 117.0 COG3103@1|root,COG4991@2|Bacteria,1R3Z6@1224|Proteobacteria,2TVS4@28211|Alphaproteobacteria 28211|Alphaproteobacteria T sh3 domain protein - - - - - - - - - - - - SH3_3 k141_8912_5 411462.DORLON_00967 4.11e-18 85.5 2E66T@1|root,330VC@2|Bacteria,1VHCY@1239|Firmicutes,24MYI@186801|Clostridia 186801|Clostridia S Psort location CytoplasmicMembrane, score - - - - - - - - - - - - - k141_8912_9 1397527.Q670_04745 5.28e-107 315.0 COG0778@1|root,COG0778@2|Bacteria,1PG8V@1224|Proteobacteria,1RQ9U@1236|Gammaproteobacteria,1XK5K@135619|Oceanospirillales 135619|Oceanospirillales C nitroreductase - - - - - - - - - - - - Nitroreductase k141_37287_1 1279017.AQYJ01000027_gene1712 0.0 935.0 COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,1SZQQ@1236|Gammaproteobacteria,46CZH@72275|Alteromonadaceae 1236|Gammaproteobacteria S Putative modulator of DNA gyrase - - - ko:K03568 - - - - ko00000,ko01002 - - - PmbA_TldD k141_37287_2 1279017.AQYJ01000027_gene1713 1.64e-262 726.0 COG0312@1|root,COG0312@2|Bacteria,1QM7I@1224|Proteobacteria,1S060@1236|Gammaproteobacteria,46AED@72275|Alteromonadaceae 1236|Gammaproteobacteria S Putative modulator of DNA gyrase - - - - - - - - - - - - PmbA_TldD k141_24393_1 1116375.VEJY3_14440 1.03e-170 480.0 COG0608@1|root,COG0608@2|Bacteria,1N37P@1224|Proteobacteria,1RQTR@1236|Gammaproteobacteria,1XTYY@135623|Vibrionales 135623|Vibrionales L single-stranded DNA 5'-3' exodeoxyribonuclease activity - - - - - - - - - - - - - k141_16066_1 745776.DGo_CA0155 1.6e-14 78.2 COG4222@1|root,COG4222@2|Bacteria,1WN8P@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S Esterase-like activity of phytase - - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - GDPD,Phytase-like k141_33946_1 1116375.VEJY3_06830 1.64e-187 523.0 COG0745@1|root,COG2197@1|root,COG0745@2|Bacteria,COG2197@2|Bacteria,1MVNV@1224|Proteobacteria,1RQHK@1236|Gammaproteobacteria,1Y0A8@135623|Vibrionales 135623|Vibrionales K helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE,Response_reg k141_33946_2 1116375.VEJY3_21236 4.96e-22 89.7 COG3015@1|root,COG3015@2|Bacteria 2|Bacteria MP regulation of cell-substrate adhesion - - - - - - - - - - - - META,NlpE k141_18587_2 666509.RCA23_c24890 8.92e-28 127.0 COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,2TSGE@28211|Alphaproteobacteria 28211|Alphaproteobacteria U COG0457 FOG TPR repeat - - - - - - - - - - - - Sulfotransfer_3,TPR_1,TPR_11,TPR_12,TPR_16,TPR_2,TPR_6,TPR_8 k141_35151_2 1279017.AQYJ01000027_gene1891 3.05e-184 512.0 COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,1RN4H@1236|Gammaproteobacteria,464CC@72275|Alteromonadaceae 1236|Gammaproteobacteria L Exodeoxyribonuclease III crc - 3.1.11.2 ko:K01142 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Exo_endo_phos k141_35151_4 1042377.AFPJ01000028_gene2290 1.48e-136 394.0 COG1561@1|root,COG1561@2|Bacteria,1MWRA@1224|Proteobacteria,1RMAB@1236|Gammaproteobacteria,464U7@72275|Alteromonadaceae 1236|Gammaproteobacteria S stress-induced protein yicC GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009022,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:0140101,GO:1901360,GO:1901361,GO:1901575 - - - - - - - - - - DUF1732,YicC_N k141_35151_5 1453501.JELR01000002_gene1205 0.0 1063.0 COG1404@1|root,COG5640@1|root,COG1404@2|Bacteria,COG5640@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria,464PM@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG1404 Subtilisin-like serine proteases - GO:0005575,GO:0005576 - ko:K14645 ko02024,map02024 - - - ko00000,ko00001,ko01000,ko01002,ko03110 - - - PKD,PPC,P_proprotein,Peptidase_S8 k141_35151_6 1453501.JELR01000001_gene2236 3.67e-118 355.0 COG1538@1|root,COG1538@2|Bacteria,1NEZC@1224|Proteobacteria,1RPC5@1236|Gammaproteobacteria,465NY@72275|Alteromonadaceae 1236|Gammaproteobacteria MU Outer membrane efflux protein czcC - - ko:K15725 - - - - ko00000,ko02000 1.B.17.2.2 - - OEP k141_35151_7 1453501.JELR01000001_gene2237 2.85e-165 477.0 COG0845@1|root,COG0845@2|Bacteria,1MX8W@1224|Proteobacteria,1RP9Q@1236|Gammaproteobacteria,466XV@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0845 Membrane-fusion protein - - - - - - - - - - - - HlyD_D23 k141_35151_8 1453501.JELR01000001_gene2238 0.0 1600.0 COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,1SP6I@1236|Gammaproteobacteria,46516@72275|Alteromonadaceae 1236|Gammaproteobacteria P Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family helA - - ko:K15726 - - - - ko00000,ko02000 2.A.6.1.2 - - ACR_tran k141_35151_11 1453501.JELR01000002_gene1203 2.72e-79 241.0 COG1309@1|root,COG1309@2|Bacteria,1RHF5@1224|Proteobacteria,1S8K9@1236|Gammaproteobacteria,468RJ@72275|Alteromonadaceae 1236|Gammaproteobacteria K Transcriptional regulator - - - - - - - - - - - - TetR_C_13,TetR_N k141_35151_12 1279017.AQYJ01000027_gene1885 6.75e-203 572.0 COG3000@1|root,COG3000@2|Bacteria,1NR7X@1224|Proteobacteria,1RQDX@1236|Gammaproteobacteria,46582@72275|Alteromonadaceae 1236|Gammaproteobacteria I Sterol desaturase - - - - - - - - - - - - FA_hydroxylase k141_35151_13 1453501.JELR01000002_gene1201 6.41e-107 312.0 COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,1RN09@1236|Gammaproteobacteria,466I4@72275|Alteromonadaceae 1236|Gammaproteobacteria F Essential for recycling GMP and indirectly, cGMP gmk GO:0003674,GO:0003824,GO:0004385,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_2813,iPC815.YPO0040,iSBO_1134.SBO_3729,iSFV_1184.SFV_3881,iSFxv_1172.SFxv_4016,iUTI89_1310.UTI89_C4193 Guanylate_kin k141_35151_14 1279017.AQYJ01000027_gene1883 2.44e-41 137.0 COG1758@1|root,COG1758@2|Bacteria,1N6TX@1224|Proteobacteria,1SCSR@1236|Gammaproteobacteria,468P0@72275|Alteromonadaceae 1236|Gammaproteobacteria K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits rpoZ GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb6 k141_35151_15 1279017.AQYJ01000027_gene1882 0.0 1273.0 COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,1RN3H@1236|Gammaproteobacteria,464Q0@72275|Alteromonadaceae 1236|Gammaproteobacteria KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance spoT GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0015949,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5,3.1.7.2 ko:K00951,ko:K01139 ko00230,map00230 - R00336,R00429 RC00002,RC00078 ko00000,ko00001,ko01000,ko03009 - - iECNA114_1301.ECNA114_3794,iECOK1_1307.ECOK1_4092,iECP_1309.ECP_3748,iECS88_1305.ECS88_4065,iECSF_1327.ECSF_3486,iLF82_1304.LF82_2165,iNRG857_1313.NRG857_18145,iUMN146_1321.UM146_18405,iUTI89_1310.UTI89_C4195,ic_1306.c4475 ACT_4,HD_4,RelA_SpoT,TGS k141_35151_17 1279017.AQYJ01000027_gene1880 1.07e-162 461.0 COG0451@1|root,COG0451@2|Bacteria,1MWVJ@1224|Proteobacteria,1RNDT@1236|Gammaproteobacteria,4673H@72275|Alteromonadaceae 1236|Gammaproteobacteria GM COG0451 Nucleoside-diphosphate-sugar epimerases - - - - - - - - - - - - Epimerase,NAD_binding_10,RmlD_sub_bind k141_35151_20 1279017.AQYJ01000027_gene1877 0.0 1097.0 COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,1RMMQ@1236|Gammaproteobacteria,46544@72275|Alteromonadaceae 1236|Gammaproteobacteria L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) recG GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecG_wedge k141_17248_1 218284.CCDN010000006_gene3569 7.35e-15 73.6 COG2199@1|root,COG3706@2|Bacteria,1V2QN@1239|Firmicutes,4HFY9@91061|Bacilli,1ZS2E@1386|Bacillus 91061|Bacilli T 5TMR of 5TMR-LYT yhcK1 - 2.7.7.65 ko:K18967 - - - - ko00000,ko01000,ko02000 9.B.34.1.1 - - 5TM-5TMR_LYT,GGDEF k141_17248_2 218284.CCDN010000006_gene3568 1.1e-87 272.0 COG3227@1|root,COG3227@2|Bacteria,1TP08@1239|Firmicutes,4H9S6@91061|Bacilli,1ZCEP@1386|Bacillus 91061|Bacilli E Peptidase M4 nprE GO:0005575,GO:0005576 3.4.24.28 ko:K01400 - - - - ko00000,ko01000,ko01002 - - - FTP,PPC,PepSY,Peptidase_M4,Peptidase_M4_C k141_14827_2 523791.Kkor_1995 5.95e-29 112.0 COG1131@1|root,COG1131@2|Bacteria,1R3XF@1224|Proteobacteria,1S0MM@1236|Gammaproteobacteria 1236|Gammaproteobacteria V abc transporter atp-binding protein nodI - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_16067_1 1278073.MYSTI_00618 7.96e-15 79.3 COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1MVEU@1224|Proteobacteria,43AGY@68525|delta/epsilon subdivisions,2X5WX@28221|Deltaproteobacteria,2YWWR@29|Myxococcales 28221|Deltaproteobacteria KLT serine threonine protein kinase - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - Pkinase,TPR_10,TPR_12,zf-HC2 k141_29105_1 1116375.VEJY3_13330 1.24e-120 353.0 COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,1RMS3@1236|Gammaproteobacteria,1XTCE@135623|Vibrionales 135623|Vibrionales CH COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases ubiH - - ko:K03185 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04989,R08773 RC02670 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_3 k141_29105_2 1116375.VEJY3_13325 6.35e-276 756.0 COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,1RND5@1236|Gammaproteobacteria,1XU9H@135623|Vibrionales 135623|Vibrionales CH COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases visC - - ko:K18800 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04987,R08768 RC00046 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_3 k141_29105_3 1116375.VEJY3_13320 6.15e-42 137.0 2CTIP@1|root,32STK@2|Bacteria,1MZ8V@1224|Proteobacteria,1SEQR@1236|Gammaproteobacteria,1XYB9@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF1107) - - - - - - - - - - - - DUF1107 k141_29105_4 1280001.BAOA01000068_gene2675 4.44e-97 283.0 COG2606@1|root,COG2606@2|Bacteria,1QJRS@1224|Proteobacteria,1SHYA@1236|Gammaproteobacteria,1XXFV@135623|Vibrionales 135623|Vibrionales S Aminoacyl-tRNA editing domain - - - ko:K19055 - - - - ko00000,ko01000,ko03016 - - - tRNA_edit k141_29105_5 1219076.N646_1675 4.35e-199 555.0 COG0354@1|root,COG0354@2|Bacteria,1N852@1224|Proteobacteria,1RPWB@1236|Gammaproteobacteria,1XTWH@135623|Vibrionales 135623|Vibrionales J Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication ygfZ GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0051186,GO:0071840 - ko:K06980 - - - - ko00000,ko03016 - - - GCV_T k141_29105_6 1116375.VEJY3_13305 6.19e-59 181.0 COG2938@1|root,COG2938@2|Bacteria,1N7P4@1224|Proteobacteria,1SCKB@1236|Gammaproteobacteria,1XXUM@135623|Vibrionales 135623|Vibrionales S An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well sdhE GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016999,GO:0017144,GO:0018065,GO:0018293,GO:0019538,GO:0019752,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350,GO:1901564 - ko:K09159 - - - - ko00000,ko02048 - - - Sdh5 k141_36178_1 1405.DJ92_4552 1.08e-95 286.0 COG2720@1|root,COG2720@2|Bacteria,1TQM8@1239|Firmicutes,4HBHS@91061|Bacilli,1ZD12@1386|Bacillus 91061|Bacilli V VanW like protein - - - ko:K18346 ko01502,ko02020,map01502,map02020 M00651 - - ko00000,ko00001,ko00002,ko01504 - - - VanW k141_30200_1 1056820.KB900640_gene278 2.09e-87 263.0 COG1075@1|root,COG1075@2|Bacteria,1P9JY@1224|Proteobacteria,1RYH4@1236|Gammaproteobacteria,2PQ8G@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria S acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - - - - - - - - - - - k141_24394_1 218284.CCDN010000001_gene24 2.85e-157 474.0 COG1196@1|root,COG1196@2|Bacteria,1TPJV@1239|Firmicutes,4HB89@91061|Bacilli,1ZAWM@1386|Bacillus 91061|Bacilli D Required for chromosome condensation and partitioning smc GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K03529 - - - - ko00000,ko03036 - - - SMC_N,SMC_hinge k141_13916_1 1116375.VEJY3_06360 4.75e-169 486.0 COG1164@1|root,COG1164@2|Bacteria,1MXAC@1224|Proteobacteria,1S6M5@1236|Gammaproteobacteria,1XVUU@135623|Vibrionales 135623|Vibrionales E COG1164 Oligoendopeptidase F - - - ko:K08602 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M3,Peptidase_M3_N k141_27014_1 1116375.VEJY3_02885 1.68e-116 345.0 COG1757@1|root,COG1757@2|Bacteria,1MX0T@1224|Proteobacteria,1RN8E@1236|Gammaproteobacteria,1XSIG@135623|Vibrionales 135623|Vibrionales C Na H antiporter - - - - - - - - - - - - Na_H_antiporter k141_27014_2 1116375.VEJY3_02880 1.26e-147 421.0 COG3246@1|root,COG3246@2|Bacteria,1MXEF@1224|Proteobacteria,1S304@1236|Gammaproteobacteria,1XUJZ@135623|Vibrionales 135623|Vibrionales S beta-keto acid cleavage enzyme - - - - - - - - - - - - BKACE k141_27014_3 1116375.VEJY3_02875 7.65e-307 838.0 COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,1RNW9@1236|Gammaproteobacteria,1XUZX@135623|Vibrionales 135623|Vibrionales E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - - - - - - - - - - Aminotran_3 k141_27014_4 223926.28805612 4.31e-160 461.0 COG3675@1|root,COG3675@2|Bacteria,1PI8G@1224|Proteobacteria,1RP6A@1236|Gammaproteobacteria,1XWBS@135623|Vibrionales 135623|Vibrionales I Lipase (class 3) VP0626 - - - - - - - - - - - Lipase_3 k141_27014_5 223926.28805611 1.51e-42 147.0 2DPN7@1|root,332RB@2|Bacteria,1N6Z9@1224|Proteobacteria,1SCUN@1236|Gammaproteobacteria,1XXC6@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_27014_6 1116375.VEJY3_02865 9.21e-116 338.0 COG0583@1|root,COG0583@2|Bacteria,1MV11@1224|Proteobacteria,1SYIC@1236|Gammaproteobacteria,1XSMV@135623|Vibrionales 135623|Vibrionales K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_9014_1 1453501.JELR01000005_gene1591 5.83e-24 100.0 COG3119@1|root,COG3119@2|Bacteria 2|Bacteria P arylsulfatase activity - - - - - - - - - - - - HXXSHH,Metalloenzyme,Phosphodiest,Sulfatase k141_9014_2 1453501.JELR01000005_gene1590 1.83e-198 601.0 COG1520@1|root,COG2133@1|root,COG1520@2|Bacteria,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,1RNGN@1236|Gammaproteobacteria,465UX@72275|Alteromonadaceae 1236|Gammaproteobacteria G Glucose / Sorbosone dehydrogenase - - - - - - - - - - - - Big_2,CBM26,Cytochrome_CBB3,GSDH,PSCyt3,PSD2,PSD3,PSD4,PSD5 k141_12714_1 1042377.AFPJ01000007_gene1933 1.18e-28 117.0 COG2304@1|root,COG2304@2|Bacteria,1MW51@1224|Proteobacteria,1RMD3@1236|Gammaproteobacteria,464YJ@72275|Alteromonadaceae 1236|Gammaproteobacteria K protein containing a von Willebrand factor type A (vWA) domain - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - TPR_1,TPR_2,VWA_2 k141_33948_1 218284.CCDN010000005_gene3314 6.63e-50 159.0 2E36V@1|root,32Y6J@2|Bacteria,1VFDU@1239|Firmicutes,4HY6K@91061|Bacilli,1ZHWX@1386|Bacillus 91061|Bacilli S Stage VI sporulation protein F spoVIF - - - - - - - - - - - SpoVIF k141_17249_2 666686.B1NLA3E_18545 1.66e-52 176.0 COG1168@1|root,COG1168@2|Bacteria,1TP5G@1239|Firmicutes,4H9PE@91061|Bacilli,1ZCQC@1386|Bacillus 91061|Bacilli E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities patB - 4.4.1.8 ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 - R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 k141_23339_2 218284.CCDN010000001_gene189 4.72e-41 135.0 2F8H8@1|root,3082J@2|Bacteria,1U2PE@1239|Firmicutes,4ICCB@91061|Bacilli,1ZK9K@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_18588_1 218284.CCDN010000002_gene2038 2.2e-177 524.0 COG0457@1|root,COG0457@2|Bacteria,1UATF@1239|Firmicutes,4HE1D@91061|Bacilli,1ZBPM@1386|Bacillus 91061|Bacilli S ATPase. Has a role at an early stage in the morphogenesis of the spore coat - - - - - - - - - - - - Dynamin_N,TPR_8 k141_22020_2 1117647.M5M_14220 8.18e-63 194.0 COG0346@1|root,COG0346@2|Bacteria,1RGZ8@1224|Proteobacteria,1S66M@1236|Gammaproteobacteria,1J6AK@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E COG0346 Lactoylglutathione lyase and related lyases yaeR - - ko:K08234 - - - - ko00000 - - - Glyoxalase k141_16068_1 997296.PB1_13519 2.32e-61 202.0 COG0707@1|root,COG0707@2|Bacteria,1TR07@1239|Firmicutes,4HBKJ@91061|Bacilli,1ZQUQ@1386|Bacillus 91061|Bacilli M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA) ugtP GO:0003674,GO:0003824,GO:0008194,GO:0016740,GO:0016757,GO:0016758,GO:0035251,GO:0046527,GO:0047228 2.4.1.315 ko:K03429 ko00561,ko01100,map00561,map01100 - R02689,R04377 RC00005,RC00059 ko00000,ko00001,ko01000,ko01003 - GT28 - Glyco_tran_28_C,Glycos_transf_1,MGDG_synth k141_13917_1 42565.FP66_12395 8.56e-71 219.0 2BVTQ@1|root,2Z7J9@2|Bacteria,1P01Z@1224|Proteobacteria,1RNNB@1236|Gammaproteobacteria,1XIR7@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF2797) - - - - - - - - - - - - DUF2797 k141_25742_4 1116375.VEJY3_01600 4.2e-216 598.0 COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,1RPR7@1236|Gammaproteobacteria,1XTYZ@135623|Vibrionales 135623|Vibrionales H Belongs to the FPP GGPP synthase family ispB - 2.5.1.90 ko:K02523 ko00900,ko01110,map00900,map01110 - R09248 RC00279 ko00000,ko00001,ko01000,ko01006 - - - polyprenyl_synt k141_25742_5 29495.EA26_02600 2.12e-67 204.0 COG0261@1|root,COG0261@2|Bacteria,1MZEW@1224|Proteobacteria,1S5VB@1236|Gammaproteobacteria,1XXAQ@135623|Vibrionales 135623|Vibrionales J This protein binds to 23S rRNA in the presence of protein L20 rplU GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02888 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L21p k141_25742_7 1116375.VEJY3_01615 3.08e-266 731.0 COG0536@1|root,COG0536@2|Bacteria,1MUGZ@1224|Proteobacteria,1RMFQ@1236|Gammaproteobacteria,1XSG0@135623|Vibrionales 135623|Vibrionales S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control obg GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03979 - - - - ko00000,ko01000,ko03009 - - - GTP1_OBG,MMR_HSR1 k141_25742_8 1116375.VEJY3_01620 1.29e-168 473.0 COG2966@1|root,COG2966@2|Bacteria,1NH2X@1224|Proteobacteria,1RN1Q@1236|Gammaproteobacteria,1XSCP@135623|Vibrionales 135623|Vibrionales S Putative threonine/serine exporter yjjP - - - - - - - - - - - ThrE k141_25742_9 223926.28805315 3.1e-107 309.0 COG3610@1|root,COG3610@2|Bacteria,1RAWK@1224|Proteobacteria,1S2KX@1236|Gammaproteobacteria,1XX2R@135623|Vibrionales 135623|Vibrionales S Threonine/Serine exporter, ThrE - - - - - - - - - - - - ThrE_2 k141_25742_10 674977.VMC_03350 5e-104 301.0 COG0262@1|root,COG0262@2|Bacteria,1RH0P@1224|Proteobacteria,1S5VH@1236|Gammaproteobacteria,1XX0F@135623|Vibrionales 135623|Vibrionales H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis folA - 1.5.1.3 ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 M00126,M00840 R00936,R00937,R00939,R00940,R02235,R02236,R11765 RC00109,RC00110,RC00158 ko00000,ko00001,ko00002,ko01000 - - - DHFR_1 k141_25742_11 1116375.VEJY3_01635 3.53e-185 515.0 COG0639@1|root,COG0639@2|Bacteria,1MV10@1224|Proteobacteria,1RPUJ@1236|Gammaproteobacteria,1XTGT@135623|Vibrionales 135623|Vibrionales T Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP apaH GO:0003674,GO:0003824,GO:0004551,GO:0004721,GO:0006139,GO:0006464,GO:0006470,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008138,GO:0008150,GO:0008152,GO:0008796,GO:0008803,GO:0009987,GO:0015949,GO:0016311,GO:0016462,GO:0016787,GO:0016788,GO:0016791,GO:0016817,GO:0016818,GO:0019538,GO:0034641,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0046483,GO:0055086,GO:0071704,GO:0140096,GO:1901360,GO:1901564 3.6.1.41 ko:K01525 ko00230,map00230 - R00125 RC00002 ko00000,ko00001,ko01000 - - - Metallophos k141_25742_12 1219076.N646_2524 2.94e-87 256.0 COG2967@1|root,COG2967@2|Bacteria,1MZ2Z@1224|Proteobacteria,1S8SE@1236|Gammaproteobacteria,1XXD5@135623|Vibrionales 135623|Vibrionales P protein affecting Mg2 Co2 transport apaG - - ko:K06195 - - - - ko00000 - - - DUF525 k141_25742_13 1219076.N646_2525 1.64e-195 541.0 COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,1RMHW@1236|Gammaproteobacteria,1XTN7@135623|Vibrionales 135623|Vibrionales J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits ksgA GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 ko:K02528 - - R10716 RC00003,RC03257 ko00000,ko01000,ko03009 - - - RrnaAD k141_25742_14 674977.VMC_03310 1.33e-228 630.0 COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,1RNZV@1236|Gammaproteobacteria,1XT1M@135623|Vibrionales 135623|Vibrionales H Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) pdxA GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.1.1.262 ko:K00097 ko00750,ko01100,map00750,map01100 M00124 R05681,R05837,R07406 RC00089,RC00675,RC01475 ko00000,ko00001,ko00002,ko01000 - - - PdxA k141_25742_15 1116375.VEJY3_01655 1.39e-278 765.0 COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,1RMWU@1236|Gammaproteobacteria,1XV5K@135623|Vibrionales 135623|Vibrionales M Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation surA GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0006457,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 ko:K03771 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_3,SurA_N k141_25742_16 1116375.VEJY3_01660 0.0 1460.0 COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,1RQEX@1236|Gammaproteobacteria,1XSAA@135623|Vibrionales 135623|Vibrionales M Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane lptD GO:0008150,GO:0009636,GO:0042221,GO:0050896 - ko:K04744 - - - - ko00000,ko02000 1.B.42.1 - - OstA,OstA_C k141_25742_17 1116375.VEJY3_01665 2.76e-170 479.0 COG1076@1|root,COG1076@2|Bacteria,1N270@1224|Proteobacteria,1RP0P@1236|Gammaproteobacteria,1XSR9@135623|Vibrionales 135623|Vibrionales O Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host djlA - - ko:K05801 - - - - ko00000,ko03110 - - - DnaJ,TerB k141_32621_1 1283287.KB822582_gene2893 2.67e-74 237.0 COG1757@1|root,COG1757@2|Bacteria,2I8CQ@201174|Actinobacteria 201174|Actinobacteria C Na H antiporter nhaC - - ko:K03315 - - - - ko00000,ko02000 2.A.35 - - Na_H_antiporter k141_20778_1 1049564.TevJSym_ad00780 2.09e-88 278.0 COG0187@1|root,COG0187@2|Bacteria,1MVH1@1224|Proteobacteria,1RMCI@1236|Gammaproteobacteria,1J4HN@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parE GO:0000819,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006276,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007059,GO:0007062,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0022402,GO:0030541,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0098813,GO:0140097,GO:1901360 - ko:K02622 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim k141_6629_1 1042377.AFPJ01000007_gene1747 3.95e-95 282.0 COG1309@1|root,COG1309@2|Bacteria,1NM93@1224|Proteobacteria,1S56I@1236|Gammaproteobacteria,46DG9@72275|Alteromonadaceae 1236|Gammaproteobacteria K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N k141_10326_2 1279017.AQYJ01000028_gene2110 5.26e-149 428.0 COG2962@1|root,COG2962@2|Bacteria,1MX5G@1224|Proteobacteria,1RMAC@1236|Gammaproteobacteria,465R2@72275|Alteromonadaceae 1236|Gammaproteobacteria S RarD protein rarD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016021,GO:0031224,GO:0044425,GO:0044464,GO:0071944 - ko:K05786 - - - - ko00000,ko02000 2.A.7.7 - - EamA k141_33969_1 1294265.JCM21738_2601 2.87e-70 216.0 COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,4H9TI@91061|Bacilli,1ZBG7@1386|Bacillus 91061|Bacilli I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol ywiE GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0032048,GO:0032049,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 - ko:K06131 ko00564,ko01100,map00564,map01100 - R07390 RC00017 ko00000,ko00001,ko01000 - - iYO844.BSU37240 PLDc_2,PLDc_N k141_33969_2 1294265.JCM21738_2600 1.23e-55 178.0 COG2846@1|root,COG2846@2|Bacteria,1UYJV@1239|Firmicutes,4HE93@91061|Bacilli,1ZE2Y@1386|Bacillus 91061|Bacilli D Di-iron-containing protein involved in the repair of iron-sulfur clusters scdA GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0030091,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050896,GO:0071704,GO:1901564 - ko:K07322 - - - - ko00000 - - - Hemerythrin,ScdA_N k141_16090_1 1499967.BAYZ01000055_gene4863 2.37e-53 180.0 COG0331@1|root,COG0331@2|Bacteria,2NP3V@2323|unclassified Bacteria 2|Bacteria I malonyl CoA-acyl carrier protein transacylase fabD - 2.3.1.39 ko:K00645 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082 R01626,R11671 RC00004,RC00039,RC02727 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyl_transf_1 k141_5527_1 1294265.JCM21738_3758 2.86e-83 247.0 2BVDP@1|root,32QTK@2|Bacteria,1V9E2@1239|Firmicutes,4HJ1S@91061|Bacilli,1ZFUF@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2521) ybaK - - - - - - - - - - - DUF2521 k141_5527_2 1294265.JCM21738_3759 1e-116 337.0 COG0860@1|root,COG0860@2|Bacteria,1TQ74@1239|Firmicutes,4HAV3@91061|Bacilli,1ZBJ8@1386|Bacillus 91061|Bacilli M n-acetylmuramoyl-L-alanine amidase cwlD GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - Amidase_3 k141_6630_1 1294265.JCM21738_5086 4.56e-41 148.0 COG2766@1|root,COG2766@2|Bacteria,1TRTW@1239|Firmicutes,4HA8A@91061|Bacilli,1ZBM9@1386|Bacillus 91061|Bacilli T Ser protein kinase prkA - - ko:K07180 - - - - ko00000 - - - AAA_PrkA,PrkA k141_6630_2 1294265.JCM21738_5087 1.12e-35 127.0 COG0778@1|root,COG0778@2|Bacteria,1UB8S@1239|Firmicutes,4HEGP@91061|Bacilli,1ZBQ3@1386|Bacillus 91061|Bacilli C Oxidoreductase nfrA1 - 1.5.1.38 ko:K19285 ko00740,ko01100,map00740,map01100 - R05706 RC00126 ko00000,ko00001,ko01000 - - - Nitroreductase k141_11476_1 550540.Fbal_3017 1.84e-98 310.0 COG0610@1|root,COG0610@2|Bacteria,1QX4Z@1224|Proteobacteria,1T4Q5@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Z1 domain - - - - - - - - - - - - Z1 k141_11476_3 1116375.VEJY3_04010 4.68e-199 552.0 COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,1RNSW@1236|Gammaproteobacteria,1XTV0@135623|Vibrionales 135623|Vibrionales F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate folD GO:0003674,GO:0003824,GO:0004477,GO:0004486,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0019752,GO:0034641,GO:0042558,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0055114,GO:0071704,GO:1901360,GO:1901564 1.5.1.5,3.5.4.9 ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R01220,R01655 RC00202,RC00578 ko00000,ko00001,ko00002,ko01000 - - - THF_DHG_CYH,THF_DHG_CYH_C k141_11476_4 1116375.VEJY3_03995 5.2e-226 623.0 COG2951@1|root,COG2951@2|Bacteria,1MUZ3@1224|Proteobacteria,1RMQ6@1236|Gammaproteobacteria,1XTUP@135623|Vibrionales 135623|Vibrionales M Membrane-bound lytic murein transglycosylase B mltB - - ko:K08305 - - - - ko00000,ko01000,ko01011 - GH103 - SLT_2 k141_11476_5 1116375.VEJY3_03990 1.24e-57 179.0 COG3100@1|root,COG3100@2|Bacteria,1N83J@1224|Proteobacteria,1SCCD@1236|Gammaproteobacteria,1XYIW@135623|Vibrionales 135623|Vibrionales S YcgL domain-containing protein ycgL - - ko:K09902 - - - - ko00000 - - - YcgL k141_11476_6 1280001.BAOA01000047_gene1755 3.22e-139 395.0 COG0850@1|root,COG0850@2|Bacteria,1RE6K@1224|Proteobacteria,1T0SI@1236|Gammaproteobacteria,1XTUT@135623|Vibrionales 135623|Vibrionales D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization minC - - ko:K03610 - - - - ko00000,ko03036,ko04812 - - - MinC_C,MinC_N k141_12736_1 218284.CCDN010000005_gene3291 1.7e-171 493.0 COG1164@1|root,COG1164@2|Bacteria,1TP4P@1239|Firmicutes,4HA7X@91061|Bacilli,1ZCHA@1386|Bacillus 91061|Bacilli E oligoendopeptidase F pepF GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - ko:K08602 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M3,Peptidase_M3_N k141_789_1 1042377.AFPJ01000024_gene719 1.38e-235 652.0 COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1MU8P@1224|Proteobacteria,1RQ49@1236|Gammaproteobacteria,4647W@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate ribB - 3.5.4.25,4.1.99.12 ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 M00125,M00840 R00425,R07281 RC00293,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_0516 DHBP_synthase,GTP_cyclohydro2 k141_789_4 1453501.JELR01000002_gene539 1.49e-50 170.0 COG0611@1|root,COG0611@2|Bacteria,1MU9X@1224|Proteobacteria,1RNHU@1236|Gammaproteobacteria,466CJ@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 thiL GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009030,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009229,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042357,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.16 ko:K00946 ko00730,ko01100,map00730,map01100 M00127 R00617 RC00002 ko00000,ko00001,ko00002,ko01000 - - iSFV_1184.SFV_0382 AIRS,AIRS_C k141_35191_1 1415778.JQMM01000001_gene1403 2.4e-31 119.0 COG3165@1|root,COG3165@2|Bacteria,1R1CM@1224|Proteobacteria,1S1SM@1236|Gammaproteobacteria,1J6XG@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria yigP - - ko:K03690 - - - - ko00000 - - - SCP2 k141_35191_2 1042377.AFPJ01000028_gene2239 1.95e-168 471.0 COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,1RMAU@1236|Gammaproteobacteria,464M8@72275|Alteromonadaceae 1236|Gammaproteobacteria H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) ubiE GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008425,GO:0008757,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016741,GO:0030580,GO:0032259,GO:0042180,GO:0042181,GO:0043333,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.1.1.163,2.1.1.201 ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116,M00117 R04990,R04993,R06859,R08774,R09736 RC00003,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b3833,iBWG_1329.BWG_3511,iE2348C_1286.E2348C_4147,iEC042_1314.EC042_4213,iEC55989_1330.EC55989_4310,iECDH10B_1368.ECDH10B_4024,iECDH1ME8569_1439.ECDH1ME8569_3712,iECH74115_1262.ECH74115_5274,iECIAI1_1343.ECIAI1_4028,iECIAI39_1322.ECIAI39_3162,iECO103_1326.ECO103_4330,iECO111_1330.ECO111_4661,iECO26_1355.ECO26_4752,iECSE_1348.ECSE_4121,iECSP_1301.ECSP_4888,iECUMN_1333.ECUMN_4359,iECW_1372.ECW_m4135,iECs_1301.ECs4763,iEKO11_1354.EKO11_4524,iETEC_1333.ETEC_4110,iEcDH1_1363.EcDH1_4146,iEcE24377_1341.EcE24377A_4354,iEcHS_1320.EcHS_A4057,iEcSMS35_1347.EcSMS35_4216,iEcolC_1368.EcolC_4175,iG2583_1286.G2583_4633,iJO1366.b3833,iJR904.b3833,iSBO_1134.SBO_3847,iSDY_1059.SDY_3910,iSFV_1184.SFV_3665,iSF_1195.SF3911,iSFxv_1172.SFxv_4263,iSSON_1240.SSON_4008,iS_1188.S3843,iSbBS512_1146.SbBS512_E4305,iUMNK88_1353.UMNK88_4663,iWFL_1372.ECW_m4135,iY75_1357.Y75_RS17910,iZ_1308.Z5355 Ubie_methyltran k141_35191_3 1279017.AQYJ01000027_gene1935 2e-18 84.7 COG5607@1|root,COG5607@2|Bacteria,1RH6R@1224|Proteobacteria,1S7KA@1236|Gammaproteobacteria 1236|Gammaproteobacteria S CHAD domain - - - - - - - - - - - - CHAD k141_10327_1 218284.CCDN010000001_gene1357 5.83e-158 466.0 COG0514@1|root,COG0514@2|Bacteria,1TPN5@1239|Firmicutes,4H9QP@91061|Bacilli,1ZC4U@1386|Bacillus 91061|Bacilli L DNA helicase recQ GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009378,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.6.4.12 ko:K03654 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind k141_27827_1 218284.CCDN010000001_gene605 1e-190 537.0 COG0001@1|root,COG0001@2|Bacteria,1TPNH@1239|Firmicutes,4HANQ@91061|Bacilli,1ZBUT@1386|Bacillus 91061|Bacilli H Glutamate-1-semialdehyde aminotransferase hemL - 5.4.3.8 ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02272 RC00677 ko00000,ko00001,ko00002,ko01000,ko01007 - - iSB619.SA_RS08395 Aminotran_3 k141_5528_1 218284.CCDN010000001_gene586 2.5e-70 217.0 COG0689@1|root,COG0689@2|Bacteria,1TQM3@1239|Firmicutes,4HBH3@91061|Bacilli,1ZBXN@1386|Bacillus 91061|Bacilli J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates rph GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006401,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043170,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 ko:K00989 - - - - ko00000,ko01000,ko03016 - - - Ham1p_like,RNase_PH,RNase_PH_C k141_5528_2 218284.CCDN010000001_gene587 4.9e-25 97.8 COG0127@1|root,COG0127@2|Bacteria,1V6RN@1239|Firmicutes,4HCP6@91061|Bacilli,1ZFJM@1386|Bacillus 91061|Bacilli F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions rdgB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 ko:K02428 ko00230,map00230 - R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000 - - - Ham1p_like k141_9044_2 1453501.JELR01000002_gene442 1.89e-108 312.0 COG0691@1|root,COG0691@2|Bacteria,1RDFP@1224|Proteobacteria,1S3PT@1236|Gammaproteobacteria,466RT@72275|Alteromonadaceae 1236|Gammaproteobacteria O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA smpB GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0070930,GO:0071704,GO:0097159,GO:1901363,GO:1901564 - ko:K03664 - - - - ko00000 - - - SmpB k141_9044_3 1265503.KB905163_gene2136 5.22e-18 83.6 COG0733@1|root,COG0733@2|Bacteria,1MUZJ@1224|Proteobacteria,1RPCT@1236|Gammaproteobacteria,2Q6K3@267889|Colwelliaceae 1236|Gammaproteobacteria S Sodium:neurotransmitter symporter family - - - ko:K03308 - - - - ko00000 2.A.22.4,2.A.22.5 - - SNF k141_2945_1 1453501.JELR01000002_gene691 3.95e-147 416.0 COG3751@1|root,COG3751@2|Bacteria,1RD3H@1224|Proteobacteria,1S40I@1236|Gammaproteobacteria,46712@72275|Alteromonadaceae 1236|Gammaproteobacteria O 2OG-Fe(II) oxygenase - - - ko:K07394 - - - - ko00000 - - - 2OG-FeII_Oxy_3 k141_32799_2 1042377.AFPJ01000051_gene41 6.66e-31 112.0 2DEP1@1|root,32U3R@2|Bacteria,1N4PQ@1224|Proteobacteria,1S83R@1236|Gammaproteobacteria,4696P@72275|Alteromonadaceae 1236|Gammaproteobacteria S Type VIII secretion system (T8SS), CsgF protein - - - ko:K04338 - - - - ko00000,ko02044 - - - CsgF k141_16241_1 218284.CCDN010000002_gene2040 3.82e-77 234.0 COG1595@1|root,COG1595@2|Bacteria,1VFMV@1239|Firmicutes,4HPMS@91061|Bacilli,1ZFVX@1386|Bacillus 91061|Bacilli K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_24620_2 1279017.AQYJ01000025_gene571 2.48e-66 206.0 COG3149@1|root,COG3149@2|Bacteria 2|Bacteria U Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins gspM - - ko:K02462 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSM k141_24620_3 1279017.AQYJ01000025_gene572 1.77e-126 379.0 COG3297@1|root,COG3297@2|Bacteria,1NVVW@1224|Proteobacteria,1S01F@1236|Gammaproteobacteria,4684Z@72275|Alteromonadaceae 1236|Gammaproteobacteria U GspL periplasmic domain gspL GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - ko:K02461 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - GspL_C,T2SSL k141_24620_4 1279017.AQYJ01000025_gene573 3.18e-64 208.0 COG3156@1|root,COG3156@2|Bacteria,1RAQM@1224|Proteobacteria,1S2N8@1236|Gammaproteobacteria,465H2@72275|Alteromonadaceae 1236|Gammaproteobacteria U COG3156 Type II secretory pathway, component PulK gspK GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - ko:K02460 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSK k141_11643_1 1116375.VEJY3_02560 2.24e-37 136.0 COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,1RS3J@1236|Gammaproteobacteria,1XW8U@135623|Vibrionales 135623|Vibrionales F Amidohydrolase family - - - - - - - - - - - - Amidohydro_1 k141_35369_1 1219076.N646_4276 3.01e-87 265.0 COG1087@1|root,COG1087@2|Bacteria,1MUHI@1224|Proteobacteria,1RMTU@1236|Gammaproteobacteria,1XSCZ@135623|Vibrionales 135623|Vibrionales M udp-glucose 4-epimerase galE - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - GDP_Man_Dehyd k141_35369_2 1280001.BAOA01000138_gene2049 4.51e-80 257.0 COG1629@1|root,COG4771@2|Bacteria,1MX42@1224|Proteobacteria,1RQ2K@1236|Gammaproteobacteria,1XUY7@135623|Vibrionales 135623|Vibrionales P COG1629 Outer membrane receptor proteins, mostly Fe transport hutA - - ko:K16087 - - - - ko00000,ko02000 1.B.14.2 - - Plug,TonB_dep_Rec k141_36297_1 1453501.JELR01000002_gene826 5.92e-07 50.4 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,1RNAM@1236|Gammaproteobacteria,4658T@72275|Alteromonadaceae 1236|Gammaproteobacteria G COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - - - - - - - - - - DctM k141_36297_2 1453501.JELR01000002_gene827 3.47e-98 289.0 COG3090@1|root,COG3090@2|Bacteria,1RJ8K@1224|Proteobacteria,1SA02@1236|Gammaproteobacteria,467GJ@72275|Alteromonadaceae 1236|Gammaproteobacteria G Tripartite ATP-independent periplasmic transporters, DctQ component - - - - - - - - - - - - DctQ k141_14169_2 218284.CCDN010000002_gene2555 1.37e-56 187.0 COG2211@1|root,COG2211@2|Bacteria,1UHQ3@1239|Firmicutes,4IS60@91061|Bacilli,1ZS3T@1386|Bacillus 91061|Bacilli G Major Facilitator Superfamily - - - - - - - - - - - - MFS_1,MFS_3 k141_12865_1 1223521.BBJX01000002_gene2844 5.55e-81 253.0 COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1MUXD@1224|Proteobacteria,2VI24@28216|Betaproteobacteria,4A9XD@80864|Comamonadaceae 28216|Betaproteobacteria M Belongs to the SIS family. GutQ KpsF subfamily kdsD - 5.3.1.13 ko:K06041 ko00540,ko01100,map00540,map01100 M00063 R01530 RC00541 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CBS,SIS k141_27265_1 1123020.AUIE01000022_gene3100 9.33e-19 84.0 COG3047@1|root,COG3047@2|Bacteria,1NUZJ@1224|Proteobacteria,1RRRC@1236|Gammaproteobacteria,1YFIK@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria M OmpW family ompW GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - ko:K07275 - - - - ko00000 - - - OmpW k141_27265_3 686578.AFFX01000005_gene4050 7.1e-63 211.0 COG2207@1|root,COG2207@2|Bacteria,1MX23@1224|Proteobacteria,1S2JB@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator - - - - - - - - - - - - Arabinose_bd,HTH_18 k141_27265_4 1492922.GY26_02350 2.8e-96 285.0 COG0500@1|root,COG2226@2|Bacteria,1N5DK@1224|Proteobacteria,1S3D8@1236|Gammaproteobacteria,1JBYU@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria Q ubiE/COQ5 methyltransferase family - - - - - - - - - - - - Methyltransf_11,Methyltransf_23 k141_27265_5 1279017.AQYJ01000028_gene2366 4.63e-94 280.0 COG2109@1|root,COG2109@2|Bacteria,1MUN6@1224|Proteobacteria,1RMH9@1236|Gammaproteobacteria,4642W@72275|Alteromonadaceae 1236|Gammaproteobacteria H Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids btuR GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008817,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019250,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.17 ko:K19221 ko00860,ko01100,map00860,map01100 M00122 R01492,R05220,R07268 RC00533 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b1270,iB21_1397.B21_01256,iBWG_1329.BWG_1099,iECABU_c1320.ECABU_c15500,iECBD_1354.ECBD_2352,iECB_1328.ECB_01246,iECDH10B_1368.ECDH10B_1385,iECDH1ME8569_1439.ECDH1ME8569_1209,iECD_1391.ECD_01246,iECIAI1_1343.ECIAI1_1288,iECO111_1330.ECO111_1649,iECO26_1355.ECO26_1834,iETEC_1333.ETEC_1372,iEcDH1_1363.EcDH1_2379,iEcHS_1320.EcHS_A1379,iJO1366.b1270,iJR904.b1270,iLF82_1304.LF82_0253,iNRG857_1313.NRG857_06515,iUMNK88_1353.UMNK88_1599,iY75_1357.Y75_RS06640,iYL1228.KPN_01266,ic_1306.c1735 Co_AT_N,CobA_CobO_BtuR k141_27265_6 1265313.HRUBRA_00439 9.5e-120 376.0 COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,1RMFJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB btuB - - ko:K16092 - - - - ko00000,ko02000 1.B.14.3 - - Plug,TonB_dep_Rec k141_27265_7 420324.KI911965_gene1003 6.34e-37 135.0 COG1120@1|root,COG1120@2|Bacteria,1QPWJ@1224|Proteobacteria,2U1TK@28211|Alphaproteobacteria,1JTP0@119045|Methylobacteriaceae 28211|Alphaproteobacteria HP ABC transporter - - 3.6.3.34 ko:K02013 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 - - ABC_tran k141_27923_1 1526927.Plano_0417 2.79e-63 207.0 COG0477@1|root,COG2814@2|Bacteria,1TS6K@1239|Firmicutes,4HB1V@91061|Bacilli,26D8R@186818|Planococcaceae 91061|Bacilli EGP COG0477 Permeases of the major facilitator superfamily tetA_3 - - - - - - - - - - - MFS_1,MFS_1_like,Sugar_tr k141_17376_1 218284.CCDN010000001_gene1008 2.3e-102 303.0 COG1234@1|root,COG1234@2|Bacteria,1TRGP@1239|Firmicutes,4HABM@91061|Bacilli,1ZC3J@1386|Bacillus 91061|Bacilli S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA rnz GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0042802,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 3.1.26.11 ko:K00784 ko03013,map03013 - - - ko00000,ko00001,ko01000,ko03016 - - - Lactamase_B,Lactamase_B_2 k141_14170_1 1294265.JCM21738_2659 6.69e-36 135.0 COG0559@1|root,COG4177@1|root,COG0559@2|Bacteria,COG4177@2|Bacteria,1TPMZ@1239|Firmicutes,4HBB8@91061|Bacilli,1ZBKN@1386|Bacillus 91061|Bacilli E Belongs to the binding-protein-dependent transport system permease family - - - ko:K01998,ko:K11961 ko02010,ko02024,map02010,map02024 M00237,M00323 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4,3.A.1.4.4,3.A.1.4.5 - - BPD_transp_2 k141_14170_2 1385511.N783_09225 6.61e-23 95.9 COG0332@1|root,COG0332@2|Bacteria,1TRHZ@1239|Firmicutes,4HDJ2@91061|Bacilli,2YA79@289201|Pontibacillus 91061|Bacilli I 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III - - 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACP_syn_III,ACP_syn_III_C k141_3113_1 861299.J421_4478 4.88e-202 580.0 COG1574@1|root,COG1574@2|Bacteria,1ZU9S@142182|Gemmatimonadetes 142182|Gemmatimonadetes S Amidohydrolase family - - - - - - - - - - - - Amidohydro_3 k141_27266_1 218284.CCDN010000001_gene1039 2.31e-110 327.0 COG1015@1|root,COG1015@2|Bacteria,1TP70@1239|Firmicutes,4H9RU@91061|Bacilli,1ZBG0@1386|Bacillus 91061|Bacilli G Phosphotransfer between the C1 and C5 carbon atoms of pentose deoB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008973,GO:0009987,GO:0016853,GO:0016866,GO:0016868,GO:0034641,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360 5.4.2.7 ko:K01839 ko00030,ko00230,map00030,map00230 - R01057,R02749 RC00408 ko00000,ko00001,ko01000 - - - Metalloenzyme k141_6831_1 1121091.AUMP01000040_gene1369 1.12e-80 244.0 COG0406@1|root,COG0406@2|Bacteria,1V3RC@1239|Firmicutes,4HHSJ@91061|Bacilli 91061|Bacilli G Phosphoglycerate mutase - - 5.4.2.11 ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - His_Phos_1 k141_20917_2 1453501.JELR01000001_gene2249 2.83e-97 291.0 COG3182@1|root,COG3182@2|Bacteria,1R59B@1224|Proteobacteria,1S0MV@1236|Gammaproteobacteria,46DKY@72275|Alteromonadaceae 1236|Gammaproteobacteria S conserved secreted or membrane protein precursor - - - - - - - - - - - - PepSY_TM k141_31488_1 218284.CCDN010000002_gene2053 8.34e-21 85.9 COG3610@1|root,COG3610@2|Bacteria,1V6P0@1239|Firmicutes,4HJ1Y@91061|Bacilli,1ZH5J@1386|Bacillus 91061|Bacilli S Threonine/Serine exporter, ThrE - - - - - - - - - - - - ThrE_2 k141_7906_1 997884.HMPREF1068_03632 1.1e-20 93.6 COG0608@1|root,COG0608@2|Bacteria,4NDW1@976|Bacteroidetes,2FMH0@200643|Bacteroidia,4AMVJ@815|Bacteroidaceae 976|Bacteroidetes L single-stranded-DNA-specific exonuclease recJ recJ - - ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1 k141_23599_1 981223.AIED01000003_gene2588 2.13e-09 58.2 COG0621@1|root,COG0621@2|Bacteria,1MU7N@1224|Proteobacteria,1RN46@1236|Gammaproteobacteria,3NIP5@468|Moraxellaceae 1236|Gammaproteobacteria J Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 rimO GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016782,GO:0018193,GO:0018197,GO:0018198,GO:0018339,GO:0019538,GO:0035596,GO:0035599,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901564 2.8.4.4 ko:K14441 - - R10652 RC00003,RC03217 ko00000,ko01000,ko03009 - - - Radical_SAM,TRAM,UPF0004 k141_23599_2 1279017.AQYJ01000027_gene1787 2.02e-31 120.0 COG1092@1|root,COG1092@2|Bacteria,1MUGB@1224|Proteobacteria,1RN7Z@1236|Gammaproteobacteria,464TP@72275|Alteromonadaceae 1236|Gammaproteobacteria J Specifically methylates the cytosine at position 1962 (m5C1962) of 23S rRNA rlmI - 2.1.1.191 ko:K06969 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_SAM k141_18849_1 1116375.VEJY3_16486 5.14e-69 229.0 COG1129@1|root,COG4177@1|root,COG1129@2|Bacteria,COG4177@2|Bacteria,1R9IW@1224|Proteobacteria,1T36F@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Belongs to the binding-protein-dependent transport system permease family - - - ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C,BPD_transp_2 k141_921_1 1453501.JELR01000002_gene113 1.42e-187 534.0 COG0389@1|root,COG0389@2|Bacteria,1MU5X@1224|Proteobacteria,1S28B@1236|Gammaproteobacteria,465IA@72275|Alteromonadaceae 1236|Gammaproteobacteria L Nucleotidyltransferase DNA polymerase involved in DNA repair imuB - - ko:K14161 - - - - ko00000,ko03400 - - - IMS k141_36310_1 218284.CCDN010000002_gene2874 2.01e-108 325.0 COG3333@1|root,COG3333@2|Bacteria,1TPE7@1239|Firmicutes,4HADN@91061|Bacilli,1ZBVK@1386|Bacillus 91061|Bacilli S Tripartite tricarboxylate transporter TctA family tctA - - ko:K07793 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.80.1 - - TctA k141_14179_2 1500301.JQMF01000017_gene2713 1.09e-38 150.0 COG2304@1|root,COG4249@1|root,COG2304@2|Bacteria,COG4249@2|Bacteria,1MXFD@1224|Proteobacteria,2TR94@28211|Alphaproteobacteria,4BM49@82115|Rhizobiaceae 28211|Alphaproteobacteria S C-type lectin (CTL) or carbohydrate-recognition domain (CRD) - - - - - - - - - - - - Lectin_C,Peptidase_C14 k141_14179_3 1279017.AQYJ01000027_gene1962 9.35e-77 246.0 COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,1RMGJ@1236|Gammaproteobacteria,46A3P@72275|Alteromonadaceae 1236|Gammaproteobacteria Q COG1233 Phytoene dehydrogenase and related proteins - - 1.3.99.23 ko:K09516 ko00830,map00830 - R07163 RC01835 ko00000,ko00001,ko01000 - - - Amino_oxidase,FAD_binding_6,NAD_binding_1,NAD_binding_8 k141_23615_1 1379270.AUXF01000003_gene3504 3.91e-30 114.0 COG0424@1|root,COG0424@2|Bacteria,1ZTP7@142182|Gemmatimonadetes 142182|Gemmatimonadetes D Maf-like protein - - - ko:K06287 - - - - ko00000 - - - Maf k141_15028_1 1502850.FG91_00443 1.98e-17 78.6 2C7KN@1|root,336M6@2|Bacteria,1N4WC@1224|Proteobacteria,2UE6T@28211|Alphaproteobacteria,2KCI3@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - k141_15028_2 550540.Fbal_1923 7.6e-22 89.7 2C7KN@1|root,30RKS@2|Bacteria,1N486@1224|Proteobacteria,1T684@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_37520_1 1116375.VEJY3_06830 9.07e-35 126.0 COG0745@1|root,COG2197@1|root,COG0745@2|Bacteria,COG2197@2|Bacteria,1MVNV@1224|Proteobacteria,1RQHK@1236|Gammaproteobacteria,1Y0A8@135623|Vibrionales 135623|Vibrionales K helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE,Response_reg k141_37520_2 1116375.VEJY3_06835 0.0 1629.0 COG0642@1|root,COG0745@1|root,COG1457@1|root,COG0642@2|Bacteria,COG0745@2|Bacteria,COG1457@2|Bacteria,1NWAF@1224|Proteobacteria,1T4UY@1236|Gammaproteobacteria,1Y03V@135623|Vibrionales 135623|Vibrionales T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA,Response_reg k141_11652_1 1219076.N646_4114 1.37e-129 400.0 COG4192@1|root,COG4251@1|root,COG4192@2|Bacteria,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,1T1YP@1236|Gammaproteobacteria,1XSNQ@135623|Vibrionales 135623|Vibrionales T COG0642 Signal transduction histidine kinase torS - 2.7.13.3 ko:K07647 ko02020,map02020 M00455 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - 4HB_MCP_1,HATPase_c,HisKA,Hpt,Response_reg k141_11652_2 1219076.N646_4115 3.45e-39 130.0 2B56R@1|root,31Y0N@2|Bacteria,1QKBU@1224|Proteobacteria,1TIFA@1236|Gammaproteobacteria,1XZ0Z@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_11652_3 1116375.VEJY3_19021 0.0 1392.0 28HB2@1|root,2Z7N8@2|Bacteria,1P4RV@1224|Proteobacteria,1RN0X@1236|Gammaproteobacteria,1XSU5@135623|Vibrionales 135623|Vibrionales M Fatty acid cis/trans isomerase (CTI) - - - - - - - - - - - - CTI k141_11652_4 1116375.VEJY3_19026 3.75e-184 514.0 COG0583@1|root,COG0583@2|Bacteria,1NR7K@1224|Proteobacteria,1SK5V@1236|Gammaproteobacteria,1Y2QK@135623|Vibrionales 135623|Vibrionales K Bacterial regulatory helix-turn-helix protein, lysR family - - - - - - - - - - - - HTH_1,LysR_substrate k141_11652_5 1348635.BBJY01000010_gene1403 0.0 935.0 COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,1RN2V@1236|Gammaproteobacteria,1XSD5@135623|Vibrionales 135623|Vibrionales P Arylsulfatase - - 3.1.6.1 ko:K01130 ko00140,ko00600,map00140,map00600 - R03980,R04856 RC00128,RC00231 ko00000,ko00001,ko01000 - - - Sulfatase,Sulfatase_C k141_11652_6 1116375.VEJY3_19036 0.0 881.0 COG0641@1|root,COG0641@2|Bacteria,1MX3M@1224|Proteobacteria,1RN4R@1236|Gammaproteobacteria,1XSAW@135623|Vibrionales 135623|Vibrionales C Iron-sulfur cluster-binding domain aslB - - ko:K06871 - - - - ko00000 - - - Fer4_12,Radical_SAM,SPASM k141_11652_7 1116375.VEJY3_19041 6.55e-83 253.0 COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,1RN5G@1236|Gammaproteobacteria,1XSEP@135623|Vibrionales 135623|Vibrionales S ATPase family associated with various cellular activities (AAA) - - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 k141_5711_1 471854.Dfer_4550 6.38e-47 163.0 COG0404@1|root,COG0404@2|Bacteria,4NF7S@976|Bacteroidetes,47MN7@768503|Cytophagia 976|Bacteroidetes E The glycine cleavage system catalyzes the degradation of glycine gcvT - 2.1.2.10 ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 M00532 R01221,R02300,R04125 RC00022,RC00069,RC00183,RC02834 ko00000,ko00001,ko00002,ko01000 - - - GCV_T,GCV_T_C k141_20923_1 1280001.BAOA01000065_gene2746 4.98e-133 406.0 COG4192@1|root,COG4251@1|root,COG4192@2|Bacteria,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,1T1YP@1236|Gammaproteobacteria,1XSNQ@135623|Vibrionales 135623|Vibrionales T COG0642 Signal transduction histidine kinase torS - 2.7.13.3 ko:K07647 ko02020,map02020 M00455 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - 4HB_MCP_1,HATPase_c,HisKA,Hpt,Response_reg k141_32814_1 1123257.AUFV01000020_gene2077 1.07e-75 234.0 COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,1RND6@1236|Gammaproteobacteria,1X311@135614|Xanthomonadales 135614|Xanthomonadales EP Binding-protein-dependent transport system inner membrane component - - - ko:K02034,ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - BPD_transp_1,OppC_N k141_9284_1 1453501.JELR01000002_gene394 1.58e-149 423.0 COG0412@1|root,COG0412@2|Bacteria,1RCWF@1224|Proteobacteria,1RY38@1236|Gammaproteobacteria,46D0F@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Dienelactone hydrolase family - - - - - - - - - - - - DLH k141_15029_1 1123073.KB899241_gene2339 2.08e-39 141.0 COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,1RPB4@1236|Gammaproteobacteria,1X3TB@135614|Xanthomonadales 135614|Xanthomonadales V Transport permease protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 k141_19892_1 1279017.AQYJ01000026_gene347 3.86e-13 68.9 COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,1RN5T@1236|Gammaproteobacteria,464WE@72275|Alteromonadaceae 1236|Gammaproteobacteria O Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen glnD GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008773,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019538,GO:0019752,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0070569,GO:0071704,GO:0140096,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.59 ko:K00990 ko02020,map02020 - - - ko00000,ko00001,ko01000 - - - ACT,GlnD_UR_UTase,HD,NTP_transf_2 k141_19892_2 1279017.AQYJ01000026_gene348 5.54e-198 556.0 COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,1RPGJ@1236|Gammaproteobacteria,4651N@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0436 Aspartate tyrosine aromatic aminotransferase dapC - 2.6.1.17 ko:K14261,ko:K14267 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R04475 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k141_27282_1 1192868.CAIU01000007_gene770 3.29e-20 89.7 COG2062@1|root,COG2062@2|Bacteria,1N0FX@1224|Proteobacteria,2UBYD@28211|Alphaproteobacteria,43KDI@69277|Phyllobacteriaceae 28211|Alphaproteobacteria T phosphohistidine phosphatase, SixA sixA - - ko:K08296 - - - - ko00000,ko01000 - - - His_Phos_1 k141_18873_1 1385510.N781_02325 1.25e-54 178.0 COG1309@1|root,COG1309@2|Bacteria,1V53S@1239|Firmicutes,4HIAD@91061|Bacilli 91061|Bacilli K Transcriptional regulator mtrR - - - - - - - - - - - TetR_N,WHG k141_14180_1 913865.DOT_4713 3.08e-08 52.4 COG0251@1|root,COG0251@2|Bacteria,1VVJ9@1239|Firmicutes,24G4V@186801|Clostridia 186801|Clostridia J Endoribonuclease L-PSP - - - - - - - - - - - - Ribonuc_L-PSP k141_922_1 796606.BMMGA3_06755 2.21e-15 69.7 2DFEB@1|root,2ZRJ6@2|Bacteria,1W2R8@1239|Firmicutes,4HZW7@91061|Bacilli,1ZJHB@1386|Bacillus 91061|Bacilli S Spo0E like sporulation regulatory protein - - - - - - - - - - - - SpoOE-like k141_22272_1 1279017.AQYJ01000026_gene42 3.02e-50 170.0 COG1748@1|root,COG1748@2|Bacteria,1N22C@1224|Proteobacteria,1RXXV@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Saccharopine dehydrogenase - - - - - - - - - - - - Sacchrp_dh_NADP k141_11654_1 1294265.JCM21738_452 2.25e-107 320.0 COG2204@1|root,COG2204@2|Bacteria,1VSKG@1239|Firmicutes,4HCST@91061|Bacilli,1ZCPN@1386|Bacillus 91061|Bacilli T Sigma-54 interaction domain - - - ko:K02481 - - - - ko00000,ko02022 - - - HTH_8,Response_reg,Sigma54_activat k141_34126_1 1134474.O59_000265 7.71e-41 148.0 COG2850@1|root,COG2850@2|Bacteria,1MUAC@1224|Proteobacteria,1RW6D@1236|Gammaproteobacteria,1FG6D@10|Cellvibrio 1236|Gammaproteobacteria S A domain family that is part of the cupin metalloenzyme superfamily. - - - - - - - - - - - - Cupin_8 k141_7923_1 1453501.JELR01000002_gene1095 2.03e-133 388.0 COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,1RPJE@1236|Gammaproteobacteria,465H4@72275|Alteromonadaceae 1236|Gammaproteobacteria LU Rossmann fold nucleotide-binding protein involved in DNA uptake smf - - ko:K04096 - - - - ko00000 - - - DNA_processg_A k141_7923_2 1453501.JELR01000002_gene1094 4.03e-73 232.0 COG2133@1|root,COG2133@2|Bacteria,1MVK5@1224|Proteobacteria,1RPE8@1236|Gammaproteobacteria,465NR@72275|Alteromonadaceae 1236|Gammaproteobacteria G Glucose / Sorbosone dehydrogenase - - - - - - - - - - - - GSDH k141_18874_1 1294265.JCM21738_411 2.48e-51 166.0 2BYGR@1|root,31NH1@2|Bacteria,1V9DE@1239|Firmicutes,4IR5R@91061|Bacilli,1ZRRX@1386|Bacillus 91061|Bacilli S Outer spore coat protein E (CotE) - - - ko:K06328 - - - - ko00000 - - - CotE k141_14181_1 1453501.JELR01000002_gene1234 2.66e-24 102.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPES@1236|Gammaproteobacteria,464G8@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0488 ATPase components of ABC transporters with duplicated ATPase domains yheS GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K06158 - - - - ko00000,ko03012 - - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn k141_14181_2 1453501.JELR01000002_gene1233 1.28e-19 87.0 COG2885@1|root,COG2885@2|Bacteria,1R4WG@1224|Proteobacteria,1T1FC@1236|Gammaproteobacteria,46D4T@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the ompA family oprF - - ko:K03286 - - - - ko00000,ko02000 1.B.6 - - OMP_b-brl,OmpA,OprF,TSP_3 k141_9285_1 218284.CCDN010000001_gene1002 5.42e-11 60.1 COG0835@1|root,COG0835@2|Bacteria,1V428@1239|Firmicutes,4HI77@91061|Bacilli,1ZFHY@1386|Bacillus 91061|Bacilli NT COG0835 Chemotaxis signal transduction protein - - - ko:K03408 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - CheW k141_16254_1 223926.28809062 1.1e-109 326.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1XW7E@135623|Vibrionales 135623|Vibrionales T Bacterial regulatory protein, Fis family - - - ko:K08476 ko02020,map02020 M00503 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activ_2 k141_16254_2 223926.28809061 0.0 1267.0 COG4191@1|root,COG4192@1|root,COG4191@2|Bacteria,COG4192@2|Bacteria,1RCM9@1224|Proteobacteria,1RQIN@1236|Gammaproteobacteria,1XTW1@135623|Vibrionales 135623|Vibrionales T COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system - - 2.7.13.3 ko:K08475 ko02020,map02020 M00503 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - 4HB_MCP_1,HATPase_c,HisKA,PAS_9 k141_24640_1 1279017.AQYJ01000025_gene760 7.78e-134 387.0 COG2304@1|root,COG2304@2|Bacteria,1MXQ7@1224|Proteobacteria,1RMDX@1236|Gammaproteobacteria,464NT@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein containing a von Willebrand factor type A (vWA) domain - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - VWA k141_24640_2 314287.GB2207_00760 1.12e-05 51.6 2C5QF@1|root,331W9@2|Bacteria,1N7AE@1224|Proteobacteria,1T3VH@1236|Gammaproteobacteria,1J79F@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF4381) - - - - - - - - - - - - DUF4381 k141_24640_3 1279017.AQYJ01000025_gene758 3.46e-31 118.0 COG1721@1|root,COG1721@2|Bacteria,1Q7RR@1224|Proteobacteria,1RNNP@1236|Gammaproteobacteria,466HG@72275|Alteromonadaceae 1236|Gammaproteobacteria S conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - - - - - - - - - - DUF58 k141_6857_1 318161.Sden_3305 4.06e-46 156.0 2EYIJ@1|root,33RSC@2|Bacteria,1NQWX@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_15030_1 1532558.JL39_16675 4.98e-123 367.0 COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,2U1Z0@28211|Alphaproteobacteria,4BBMN@82115|Rhizobiaceae 28211|Alphaproteobacteria L reverse transcriptase - - 2.7.7.49 ko:K00986,ko:K15342 - - - - ko00000,ko01000,ko02048,ko03400 - - - Cas_Cas1,GIIM,RVT_1 k141_3129_1 1353537.TP2_10525 2.06e-97 304.0 COG2838@1|root,COG2838@2|Bacteria,1MV6Q@1224|Proteobacteria,2TRG0@28211|Alphaproteobacteria,2XNXR@285107|Thioclava 28211|Alphaproteobacteria C NADP-specific, catalyzes the formation of 2-oxoglutarate from isocitrate or oxalosuccinate icd - 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 - - - IDH k141_32815_2 674977.VMC_00880 2.73e-47 162.0 COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,1RQ3D@1236|Gammaproteobacteria,1XYXH@135623|Vibrionales 135623|Vibrionales H AMP-binding enzyme - - 6.2.1.30 ko:K01912 ko00360,ko01120,ko05111,map00360,map01120,map05111 - R02539 RC00004,RC00014 ko00000,ko00001,ko01000 - - - AMP-binding,AMP-binding_C_2 k141_14182_1 512565.AMIS_48900 1.98e-26 106.0 COG1309@1|root,COG1309@2|Bacteria,2GZ1Y@201174|Actinobacteria,4DDXG@85008|Micromonosporales 201174|Actinobacteria K BetI-type transcriptional repressor, C-terminal - - - - - - - - - - - - TetR_C_6,TetR_N k141_25925_1 1116375.VEJY3_00755 1.43e-153 440.0 COG0457@1|root,COG0457@2|Bacteria,1MVCA@1224|Proteobacteria,1RS02@1236|Gammaproteobacteria,1XTJF@135623|Vibrionales 135623|Vibrionales S Tetratricopeptide repeat - - - - - - - - - - - - TPR_8 k141_25925_2 1116375.VEJY3_00760 2.01e-128 367.0 COG0810@1|root,COG0810@2|Bacteria,1RJPZ@1224|Proteobacteria,1S87Y@1236|Gammaproteobacteria,1XWGP@135623|Vibrionales 135623|Vibrionales M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - ko:K03832 - - - - ko00000,ko02000 2.C.1.1 - - TonB_C k141_25925_3 1116375.VEJY3_00765 1.59e-84 250.0 COG0848@1|root,COG0848@2|Bacteria,1RI4M@1224|Proteobacteria,1S4GX@1236|Gammaproteobacteria,1XX0R@135623|Vibrionales 135623|Vibrionales U TonB system transport protein ExbD2 - - - ko:K03559 - - - - ko00000,ko02000 1.A.30.2.1 - - ExbD k141_25925_4 223926.28805147 4.14e-113 325.0 COG0811@1|root,COG0811@2|Bacteria,1MX60@1224|Proteobacteria,1RRX1@1236|Gammaproteobacteria,1XV6C@135623|Vibrionales 135623|Vibrionales U TonB system transport protein ExbB2 - - - ko:K03561 - - - - ko00000,ko02000 1.A.30.2.1 - - MotA_ExbB k141_27940_1 523791.Kkor_1312 8.32e-78 245.0 COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,1RPZC@1236|Gammaproteobacteria,1XHAE@135619|Oceanospirillales 135619|Oceanospirillales J beta-lactamase - - - ko:K07576 - - - - ko00000 - - - Beta-Casp,Lactamase_B,RMMBL k141_31504_1 42565.FP66_14595 6.02e-122 357.0 COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,1RNS2@1236|Gammaproteobacteria,1XH3K@135619|Oceanospirillales 135619|Oceanospirillales P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - - - - - - - - - - Cation_efflux,ZT_dimer k141_11656_1 1405.DJ92_3393 1.23e-11 70.5 COG0601@1|root,COG0601@2|Bacteria,1TRW4@1239|Firmicutes,4HEGZ@91061|Bacilli,1ZR0R@1386|Bacillus 91061|Bacilli EP Binding-protein-dependent transport system inner membrane component - - - ko:K02033 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 k141_924_1 1123278.KB893388_gene5689 4.43e-25 100.0 COG3195@1|root,COG3195@2|Bacteria,4NNR4@976|Bacteroidetes,47QZU@768503|Cytophagia 976|Bacteroidetes S OHCU decarboxylase - - 4.1.1.97 ko:K16840 ko00230,ko01100,ko01120,map00230,map01100,map01120 M00546 R06604 RC01551 ko00000,ko00001,ko00002,ko01000 - - - OHCU_decarbox k141_924_2 330214.NIDE0054 6.13e-25 97.8 COG2351@1|root,COG2351@2|Bacteria 2|Bacteria MU hydroxyisourate hydrolase activity hiuH GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006144,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0033971,GO:0034641,GO:0042802,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:1901360,GO:1901564 3.5.2.17,4.1.1.97 ko:K07127,ko:K13485 ko00230,ko01100,ko01120,map00230,map01100,map01120 M00546 R06601,R06604 RC01551,RC03393 ko00000,ko00001,ko00002,ko01000,ko02000 9.B.35.1.2,9.B.35.2 - - Transthyretin k141_36312_1 1196031.ALEG01000039_gene1430 1.24e-96 291.0 COG0714@1|root,COG0714@2|Bacteria,1TPKR@1239|Firmicutes,4HA0T@91061|Bacilli,1ZCN3@1386|Bacillus 91061|Bacilli S ATPase family associated with various cellular activities (AAA) - - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 k141_20200_1 1279017.AQYJ01000025_gene644 2.63e-124 359.0 COG2513@1|root,COG2513@2|Bacteria,1N4VT@1224|Proteobacteria,1RMR5@1236|Gammaproteobacteria,464GF@72275|Alteromonadaceae 1236|Gammaproteobacteria G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate prpB GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006113,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0015980,GO:0016042,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019752,GO:0032787,GO:0042737,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0046421,GO:0046459,GO:0046872,GO:0055114,GO:0071704,GO:0072329,GO:1901575 4.1.3.30 ko:K03417 ko00640,map00640 - R00409 RC00286,RC00287 ko00000,ko00001,ko01000 - - iECNA114_1301.ECNA114_0319,iECP_1309.ECP_0407 PEP_mutase k141_13078_1 339670.Bamb_5079 5.1e-18 80.9 COG1028@1|root,COG1028@2|Bacteria,1MWGC@1224|Proteobacteria,2VHJE@28216|Betaproteobacteria,1K1EK@119060|Burkholderiaceae 28216|Betaproteobacteria IQ PFAM short-chain dehydrogenase reductase SDR - - - - - - - - - - - - adh_short_C2 k141_36461_1 218284.CCDN010000001_gene1947 1.69e-99 290.0 COG2249@1|root,COG2249@2|Bacteria,1V4UF@1239|Firmicutes,4HH6R@91061|Bacilli,1ZGJ6@1386|Bacillus 91061|Bacilli S NADPH-quinone reductase (modulator of drug activity B) ywrO - - ko:K11748 - - - - ko00000,ko02000 2.A.37.1.2 - - Flavodoxin_2 k141_10581_1 1294265.JCM21738_3753 7.21e-103 301.0 2EXWN@1|root,33R5S@2|Bacteria,1VSWP@1239|Firmicutes,4HV74@91061|Bacilli,1ZD92@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_3358_1 1196029.ALIM01000003_gene4325 5.36e-26 107.0 COG0714@1|root,COG0714@2|Bacteria,1TPKR@1239|Firmicutes,4HA0T@91061|Bacilli,1ZDJ1@1386|Bacillus 91061|Bacilli S COG0714 MoxR-like ATPases yeaC GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 k141_2129_1 1453501.JELR01000001_gene2480 3.73e-125 365.0 COG1472@1|root,COG1472@2|Bacteria,1MVAJ@1224|Proteobacteria,1RMQF@1236|Gammaproteobacteria,463YX@72275|Alteromonadaceae 1236|Gammaproteobacteria G Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides nagZ GO:0000270,GO:0003674,GO:0003824,GO:0004553,GO:0004563,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006807,GO:0008150,GO:0008152,GO:0009254,GO:0009273,GO:0009987,GO:0015929,GO:0016787,GO:0016798,GO:0030203,GO:0042546,GO:0043170,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901564 3.2.1.52 ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 M00628 R00022,R05963,R07809,R07810,R10831 RC00049 ko00000,ko00001,ko00002,ko01000 - - iSFV_1184.SFV_1127,iUMN146_1321.UM146_11790 Glyco_hydro_3 k141_2129_2 1279017.AQYJ01000025_gene738 2.53e-08 53.9 COG1309@1|root,COG1309@2|Bacteria,1RDIM@1224|Proteobacteria,1S4DI@1236|Gammaproteobacteria,467NJ@72275|Alteromonadaceae 1236|Gammaproteobacteria K Transcriptional regulator psrA - - - - - - - - - - - TetR_N k141_24930_1 218284.CCDN010000001_gene238 2.38e-92 270.0 COG1846@1|root,COG1846@2|Bacteria,1VA2C@1239|Firmicutes,4IGZJ@91061|Bacilli,1ZJVN@1386|Bacillus 91061|Bacilli K helix_turn_helix multiple antibiotic resistance protein - - - - - - - - - - - - MarR,MarR_2 k141_20202_1 1294265.JCM21738_4466 1.44e-28 103.0 COG3906@1|root,COG3906@2|Bacteria,1VAPW@1239|Firmicutes,4HKV7@91061|Bacilli,1ZI20@1386|Bacillus 91061|Bacilli S Belongs to the UPF0473 family yrzB - - - - - - - - - - - DUF1292 k141_29628_1 1209072.ALBT01000038_gene2301 5.87e-71 236.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MV8W@1224|Proteobacteria,1RMQA@1236|Gammaproteobacteria,1FGRS@10|Cellvibrio 1236|Gammaproteobacteria P Outer membrane protein beta-barrel family - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_7991_1 1298593.TOL_1562 1.09e-63 205.0 28IBE@1|root,2Z8DX@2|Bacteria,1NC7D@1224|Proteobacteria,1RP6N@1236|Gammaproteobacteria,1XJVD@135619|Oceanospirillales 135619|Oceanospirillales S Putative amidoligase enzyme - - - - - - - - - - - - Amidoligase_2 k141_7991_2 1232683.ADIMK_0134 1.87e-107 314.0 COG2071@1|root,COG2071@2|Bacteria,1NV5K@1224|Proteobacteria,1T05H@1236|Gammaproteobacteria,4678V@72275|Alteromonadaceae 1236|Gammaproteobacteria S glutamine amidotransferases - - - ko:K07010 - - - - ko00000,ko01002 - - - Peptidase_C26 k141_29629_1 1089545.KB913037_gene6360 3.97e-14 75.1 COG0524@1|root,COG0524@2|Bacteria,2GM3N@201174|Actinobacteria,4E0W5@85010|Pseudonocardiales 201174|Actinobacteria G pfkB family carbohydrate kinase iolC - 2.7.1.92 ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 - R05661 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB k141_16520_1 1294265.JCM21738_34 2.6e-147 426.0 COG0697@1|root,COG0697@2|Bacteria,1TP7K@1239|Firmicutes,4HBWN@91061|Bacilli,1ZB54@1386|Bacillus 91061|Bacilli EG Stage V sporulation protein AF spoVAF - - ko:K06408 - - - - ko00000 - - - GerA k141_21187_1 1007105.PT7_0189 3.32e-39 146.0 COG0438@1|root,COG0438@2|Bacteria,1MUB7@1224|Proteobacteria,2VN6W@28216|Betaproteobacteria,3T882@506|Alcaligenaceae 28216|Betaproteobacteria M Glycosyl transferase 4-like domain - - - ko:K00786 - - - - ko00000,ko01000 - - - Glyco_transf_4,Glycos_transf_1 k141_21187_2 1279017.AQYJ01000029_gene3745 4.35e-263 746.0 COG3568@1|root,COG3568@2|Bacteria,1R977@1224|Proteobacteria,1RTF2@1236|Gammaproteobacteria,466AF@72275|Alteromonadaceae 1236|Gammaproteobacteria L Type I phosphodiesterase / nucleotide pyrophosphatase - - - - - - - - - - - - Exo_endo_phos,Phosphodiest k141_16521_1 1196031.ALEG01000039_gene1299 1.78e-13 68.9 2E6FV@1|root,33136@2|Bacteria,1VH2N@1239|Firmicutes,4HQRC@91061|Bacilli,1ZNHG@1386|Bacillus 91061|Bacilli S Phage tail assembly chaperone protein, TAC - - - - - - - - - - - - Phage_TAC_12 k141_36498_1 666686.B1NLA3E_02315 3.45e-35 128.0 COG1295@1|root,COG1295@2|Bacteria,1U7HM@1239|Firmicutes,4H9MJ@91061|Bacilli,1ZCAD@1386|Bacillus 91061|Bacilli S Belongs to the UPF0761 family yihY - - ko:K07058 - - - - ko00000 - - - Virul_fac_BrkB k141_36498_2 1117379.BABA_24460 9.03e-24 95.5 COG4980@1|root,COG4980@2|Bacteria,1VGY5@1239|Firmicutes,4HPNI@91061|Bacilli,1ZIVN@1386|Bacillus 91061|Bacilli S gas vesicle protein yfkI - - - - - - - - - - - - k141_33117_1 1116375.VEJY3_22646 2.35e-218 630.0 COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,1RMYY@1236|Gammaproteobacteria,1XVUD@135623|Vibrionales 135623|Vibrionales M Mechanosensitive ion channel inner membrane domain 1 - - - ko:K22051 - - - - ko00000,ko02000 1.A.23.1.2,1.A.23.1.3 - - MS_channel,MscS_TM,MscS_porin k141_31650_1 1279017.AQYJ01000025_gene756 0.0 961.0 COG2902@1|root,COG2902@2|Bacteria,1MXNV@1224|Proteobacteria,1RQVZ@1236|Gammaproteobacteria,464UW@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG2902 NAD-specific glutamate dehydrogenase gdhB - 1.4.1.2 ko:K15371 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 - R00243 RC00006,RC02799 ko00000,ko00001,ko01000 - - - Bac_GDH,GDH_N k141_31650_2 1279017.AQYJ01000025_gene755 8.95e-204 569.0 COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,1RMCP@1236|Gammaproteobacteria,464DT@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor pyrD GO:0000166,GO:0003674,GO:0003824,GO:0004152,GO:0004158,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0010181,GO:0016020,GO:0016491,GO:0016627,GO:0016634,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0032553,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.3.5.2 ko:K00254 ko00240,ko01100,map00240,map01100 M00051 R01868 RC00051 ko00000,ko00001,ko00002,ko01000 - - iEC042_1314.EC042_1029,iECIAI39_1322.ECIAI39_2202,iECUMN_1333.ECUMN_1134,iEcSMS35_1347.EcSMS35_2174,iPC815.YPO1415,iYL1228.KPN_00974 DHO_dh k141_31650_3 1279017.AQYJ01000025_gene754 1.02e-31 112.0 COG3130@1|root,COG3130@2|Bacteria,1N761@1224|Proteobacteria,1SCIC@1236|Gammaproteobacteria,468Z0@72275|Alteromonadaceae 1236|Gammaproteobacteria J During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) rmf GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006950,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032055,GO:0032268,GO:0032269,GO:0033554,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043555,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112,GO:2000113 - ko:K03812 - - - - ko00000,ko03009 - - - RMF k141_31650_4 1279017.AQYJ01000025_gene753 3.74e-292 816.0 COG0116@1|root,COG1092@1|root,COG0116@2|Bacteria,COG1092@2|Bacteria,1MUQM@1224|Proteobacteria,1RNMH@1236|Gammaproteobacteria,4657X@72275|Alteromonadaceae 1236|Gammaproteobacteria J Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA rlmL GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.173,2.1.1.264 ko:K12297 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - Methyltrans_SAM,THUMP,UPF0020 k141_37801_1 465817.ETA_25390 3.56e-34 127.0 COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,1RMY3@1236|Gammaproteobacteria,3X5HY@551|Erwinia 1236|Gammaproteobacteria F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) tgt GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0008479,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 ko:K00773 - - R03789,R10209 RC00063 ko00000,ko01000,ko03016 - - iECW_1372.ECW_m0475,iWFL_1372.ECW_m0475 TGT k141_37801_2 414684.RC1_1041 7.15e-09 54.3 COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,2UBZ6@28211|Alphaproteobacteria,2JT97@204441|Rhodospirillales 204441|Rhodospirillales U Preprotein translocase subunit YajC yajC - - ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - YajC k141_34375_1 42565.FP66_09950 2.36e-71 218.0 COG0193@1|root,COG0193@2|Bacteria,1MX1P@1224|Proteobacteria,1RPK3@1236|Gammaproteobacteria,1XJ8C@135619|Oceanospirillales 135619|Oceanospirillales J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis pth - 3.1.1.29 ko:K01056 - - - - ko00000,ko01000,ko03012 - - - Pept_tRNA_hydro k141_34375_2 42565.FP66_09955 1.37e-13 68.6 COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,1S46A@1236|Gammaproteobacteria,1XJNP@135619|Oceanospirillales 135619|Oceanospirillales J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ctc - - ko:K02897 ko03010,map03010 M00178 - - ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L25p,Ribosomal_TL5_C k141_21188_1 1415780.JPOG01000001_gene2336 2.72e-37 143.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1X3PH@135614|Xanthomonadales 135614|Xanthomonadales T GGDEF domain - - - - - - - - - - - - EAL,GGDEF,HAMP k141_34376_2 1117379.BABA_02994 1.02e-72 225.0 2DKZH@1|root,31089@2|Bacteria,1V4EK@1239|Firmicutes,4HI9D@91061|Bacilli,1ZDRR@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_2173_1 326297.Sama_3313 4.17e-131 389.0 COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria,2Q8YZ@267890|Shewanellaceae 1236|Gammaproteobacteria O PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - - - - - - - - - - PA,PKD,Peptidase_S8 k141_37803_1 218284.CCDN010000005_gene3162 1.05e-122 354.0 COG1024@1|root,COG1024@2|Bacteria,1TRCQ@1239|Firmicutes,4HDUU@91061|Bacilli,1ZARB@1386|Bacillus 91061|Bacilli I enoyl-CoA hydratase yhaR - - - - - - - - - - - ECH_1 k141_17687_2 1453501.JELR01000001_gene2239 0.0 1054.0 COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,4656T@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG2217 Cation transport ATPase copA GO:0000041,GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006825,GO:0006950,GO:0008150,GO:0008324,GO:0009636,GO:0009987,GO:0010035,GO:0010038,GO:0010272,GO:0010273,GO:0015075,GO:0015080,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0035434,GO:0042221,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046688,GO:0046873,GO:0046915,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0060003,GO:0061687,GO:0070887,GO:0071241,GO:0071248,GO:0071280,GO:0071292,GO:0071944,GO:0090662,GO:0097501,GO:0098655,GO:0098660,GO:0098662,GO:0098754,GO:0099131,GO:1902601,GO:1990169 3.6.3.54 ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - iEC55989_1330.EC55989_0497,iECIAI1_1343.ECIAI1_0487,iECO103_1326.ECO103_0460,iECSE_1348.ECSE_0509,iECW_1372.ECW_m0557,iEKO11_1354.EKO11_3363,iWFL_1372.ECW_m0557 E1-E2_ATPase,HMA,Hydrolase k141_36502_1 1294265.JCM21738_4494 1.14e-09 57.4 COG0061@1|root,COG0061@2|Bacteria,1TRXB@1239|Firmicutes,4HCEW@91061|Bacilli,1ZB1S@1386|Bacillus 91061|Bacilli G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP nadK2 - 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 - R00104 RC00002,RC00078 ko00000,ko00001,ko01000 - - - NAD_kinase k141_36502_2 1294265.JCM21738_4495 3.37e-84 256.0 COG0616@1|root,COG0616@2|Bacteria,1TRQW@1239|Firmicutes,4HB4R@91061|Bacilli,1ZBTV@1386|Bacillus 91061|Bacilli OU signal peptide peptidase SppA sppA - - ko:K04773 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S49 k141_10607_1 1042377.AFPJ01000052_gene1583 2.53e-205 593.0 COG1629@1|root,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria,4651V@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_17688_1 1196031.ALEG01000041_gene2479 1.31e-23 98.6 COG1004@1|root,COG1004@2|Bacteria,1TQFN@1239|Firmicutes,4HADP@91061|Bacilli,1ZAP3@1386|Bacillus 91061|Bacilli M Belongs to the UDP-glucose GDP-mannose dehydrogenase family ywqF - 1.1.1.22 ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 M00014,M00129,M00361,M00362 R00286 RC00291 ko00000,ko00001,ko00002,ko01000 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N k141_16526_2 218284.CCDN010000003_gene3001 8.03e-38 135.0 COG0515@1|root,COG0515@2|Bacteria,1TSNS@1239|Firmicutes,4HBDI@91061|Bacilli,1ZBVA@1386|Bacillus 91061|Bacilli KLT serine threonine protein kinase yabT - 2.7.11.1 ko:K08884 - - - - ko00000,ko01000,ko01001 - - - Pkinase k141_36503_1 1294265.JCM21738_382 8.26e-110 329.0 COG3845@1|root,COG3845@2|Bacteria,1UYQA@1239|Firmicutes,4HVSH@91061|Bacilli,1ZS12@1386|Bacillus 91061|Bacilli S ABC transporter, ATP-binding protein mglA - 3.6.3.17 ko:K02056,ko:K06400 - M00221 - - ko00000,ko00002,ko01000,ko02000 3.A.1.2 - - ABC_tran k141_10608_1 316274.Haur_0182 0.000116 46.2 COG3063@1|root,COG3063@2|Bacteria 2|Bacteria NU photosynthesis - - - - - - - - - - - - Peptidase_C39_2,Rhomboid,TPR_16,TPR_19,TPR_8 k141_37805_1 1294265.JCM21738_1250 3.77e-94 285.0 COG4100@1|root,COG4100@2|Bacteria,1TQ88@1239|Firmicutes,4HAF5@91061|Bacilli,1ZAXI@1386|Bacillus 91061|Bacilli P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance ynbB GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0016740,GO:0016765,GO:0016829,GO:0016846 - - - - - - - - - - Met_gamma_lyase k141_16527_1 218284.CCDN010000001_gene747 4.58e-79 246.0 COG0561@1|root,COG0561@2|Bacteria,1TR3N@1239|Firmicutes,4HC8P@91061|Bacilli,1ZBP7@1386|Bacillus 91061|Bacilli S Stage IV sporulation yqfD - - ko:K06438 - - - - ko00000 - - - YqfD k141_3396_1 935845.JADQ01000019_gene4267 2.04e-29 114.0 COG0619@1|root,COG0619@2|Bacteria,1TUDZ@1239|Firmicutes,4HER7@91061|Bacilli,26RC5@186822|Paenibacillaceae 91061|Bacilli P ABC-type cobalt transport system, permease component CbiQ ykoC - - ko:K16785 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - CbiQ k141_15222_1 218284.CCDN010000001_gene802 3.73e-133 384.0 28I64@1|root,2Z898@2|Bacteria,1TQX0@1239|Firmicutes,4HF76@91061|Bacilli,1ZEIB@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_15222_2 218284.CCDN010000001_gene801 7.32e-116 348.0 COG0457@1|root,COG0705@1|root,COG0457@2|Bacteria,COG0705@2|Bacteria,1TQXT@1239|Firmicutes,4HCDF@91061|Bacilli,1ZBV7@1386|Bacillus 91061|Bacilli O membrane protein (homolog of Drosophila rhomboid) gluP - 3.4.21.105 ko:K19225 - - - - ko00000,ko01000,ko01002 - - - Rhomboid,TPR_2,TPR_8 k141_8030_1 218284.CCDN010000004_gene3119 3.3e-198 556.0 COG1301@1|root,COG1301@2|Bacteria,1TPME@1239|Firmicutes,4H9T7@91061|Bacilli,1ZCSU@1386|Bacillus 91061|Bacilli C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family gltP - - - - - - - - - - - SDF k141_2175_1 935836.JAEL01000057_gene1212 3.96e-80 240.0 COG0231@1|root,COG0231@2|Bacteria,1TR8P@1239|Firmicutes,4H9YX@91061|Bacilli,1ZAT9@1386|Bacillus 91061|Bacilli J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase efp GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02356 - - - - ko00000,ko03012 - - - EFP,EFP_N,Elong-fact-P_C k141_2175_2 218284.CCDN010000001_gene951 2.35e-39 139.0 COG0006@1|root,COG0006@2|Bacteria,1TQ44@1239|Firmicutes,4HAT7@91061|Bacilli,1ZB4P@1386|Bacillus 91061|Bacilli E COG0006 Xaa-Pro aminopeptidase yqhT - 3.4.11.9,3.4.13.9 ko:K01262,ko:K01271 - - - - ko00000,ko01000,ko01002 - - - Creatinase_N,Peptidase_M24 k141_31651_1 118168.MC7420_7553 1.29e-93 295.0 COG1807@1|root,COG1807@2|Bacteria,1G7M8@1117|Cyanobacteria,1HFAI@1150|Oscillatoriales 1117|Cyanobacteria M Dolichyl-phosphate-mannose-protein mannosyltransferase - - - - - - - - - - - - PMT_2 k141_31651_2 1121127.JAFA01000001_gene1097 3.73e-63 211.0 COG0382@1|root,COG0382@2|Bacteria,1MXCM@1224|Proteobacteria,2VKY4@28216|Betaproteobacteria,1K0JV@119060|Burkholderiaceae 28216|Betaproteobacteria H PFAM UbiA prenyltransferase - - - - - - - - - - - - HAD,UbiA k141_37807_1 1116375.VEJY3_03940 5.35e-143 420.0 COG1199@1|root,COG1199@2|Bacteria,1MVCU@1224|Proteobacteria,1RMNX@1236|Gammaproteobacteria,1XSPF@135623|Vibrionales 135623|Vibrionales KL ATP-dependent helicase yoaA - 3.6.4.12 ko:K03722 - - - - ko00000,ko01000,ko03400 - - - DEAD,DEAD_2,Helicase_C_2,ResIII k141_3397_1 218284.CCDN010000001_gene1893 7.06e-133 413.0 COG2176@1|root,COG2176@2|Bacteria,1TPAG@1239|Firmicutes,4H9RF@91061|Bacilli,1ZCIB@1386|Bacillus 91061|Bacilli L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity polC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.7.7 ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_a_NI,DNA_pol3_a_NII,DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon k141_10611_1 1042377.AFPJ01000037_gene3013 9.59e-59 193.0 COG0596@1|root,COG0596@2|Bacteria,1QTWQ@1224|Proteobacteria,1T1JQ@1236|Gammaproteobacteria,46DBF@72275|Alteromonadaceae 1236|Gammaproteobacteria S Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 k141_34378_2 997296.PB1_07132 2.8e-21 85.5 2EIS2@1|root,33CHE@2|Bacteria,1VM34@1239|Firmicutes,4HR6Z@91061|Bacilli,1ZK09@1386|Bacillus 91061|Bacilli S Inhibitor of sigma-G Gin csfB - - - - - - - - - - - Gin k141_2177_1 1217652.F954_02714 3.59e-12 65.5 COG1271@1|root,COG1271@2|Bacteria,1MV60@1224|Proteobacteria,1RN2U@1236|Gammaproteobacteria,3NK2C@468|Moraxellaceae 1236|Gammaproteobacteria C oxidase, subunit cydA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0019646,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0070069,GO:0071944,GO:0097159,GO:1901363 1.10.3.14 ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 - iPC815.YPO1117,iSFxv_1172.SFxv_0621,iS_1188.S0577 Cyt_bd_oxida_I k141_10612_1 42565.FP66_05810 8.45e-16 76.6 COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,1RMQB@1236|Gammaproteobacteria,1XHN7@135619|Oceanospirillales 135619|Oceanospirillales S Tripartite tricarboxylate transporter TctA - - - ko:K07793 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.80.1 - - TctA k141_10612_2 42565.FP66_05815 3.33e-100 291.0 2CJ0Q@1|root,32UT5@2|Bacteria,1RG6Q@1224|Proteobacteria,1S521@1236|Gammaproteobacteria,1XS8P@135619|Oceanospirillales 135619|Oceanospirillales S Tripartite tricarboxylate transporter TctB family - - - ko:K07794 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.80.1 - - TctB k141_10612_3 42565.FP66_05820 2.71e-45 154.0 COG3181@1|root,COG3181@2|Bacteria,1MXEX@1224|Proteobacteria,1RPKH@1236|Gammaproteobacteria,1XJ1G@135619|Oceanospirillales 135619|Oceanospirillales S C4-dicarboxylate ABC transporter substrate-binding protein - - - ko:K07795 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.80.1 - - TctC k141_29660_3 1279017.AQYJ01000027_gene1733 9.05e-126 362.0 COG1651@1|root,COG1651@2|Bacteria,1RGWH@1224|Proteobacteria,1S5WA@1236|Gammaproteobacteria,4653J@72275|Alteromonadaceae 1236|Gammaproteobacteria O Thiol disulfide interchange protein dsbA GO:0005575,GO:0005623,GO:0042597,GO:0044464 - ko:K03673 ko01503,map01503 M00728 - - ko00000,ko00001,ko00002,ko03110 - - - DSBA,Thioredoxin_4 k141_29660_4 1279017.AQYJ01000027_gene1734 2.8e-107 314.0 COG2863@1|root,COG2863@2|Bacteria,1N2NB@1224|Proteobacteria,1RZFP@1236|Gammaproteobacteria,466NK@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG2863 Cytochrome c553 cc4 - - - - - - - - - - - Cytochrom_C,Cytochrome_CBB3 k141_29660_5 1279017.AQYJ01000027_gene1735 4.68e-119 344.0 COG0218@1|root,COG0218@2|Bacteria,1MY3Z@1224|Proteobacteria,1RNJP@1236|Gammaproteobacteria,466MM@72275|Alteromonadaceae 1236|Gammaproteobacteria D Necessary for normal cell division and for the maintenance of normal septation engB GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03978 - - - - ko00000,ko03036 - - - MMR_HSR1 k141_29660_8 518766.Rmar_0342 2.02e-269 758.0 COG0209@1|root,COG0209@2|Bacteria,4NEHQ@976|Bacteroidetes,1FJVJ@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen nrd - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_lgC,Ribonuc_red_lgN k141_17689_1 1116375.VEJY3_20286 5.86e-177 498.0 COG4978@1|root,COG4978@2|Bacteria,1PQB5@1224|Proteobacteria,1SD79@1236|Gammaproteobacteria,1XUJM@135623|Vibrionales 135623|Vibrionales KT Polyketide cyclase / dehydrase and lipid transport - - - - - - - - - - - - GyrI-like,Polyketide_cyc2 k141_17689_2 1280001.BAOA01000070_gene2879 3.34e-11 57.4 2AWZ4@1|root,31NWW@2|Bacteria,1QKKD@1224|Proteobacteria,1TIQQ@1236|Gammaproteobacteria,1XZGT@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_17689_3 1280001.BAOA01000070_gene2875 7.86e-248 704.0 COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,1RMWN@1236|Gammaproteobacteria,1XUIC@135623|Vibrionales 135623|Vibrionales C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family nasA - - ko:K00372 ko00910,ko01120,map00910,map01120 M00531 R00798,R01106 RC02812 ko00000,ko00001,ko00002,ko01000 - - - Fer2_BFD,Molybdop_Fe4S4,Molybdopterin,Molydop_binding k141_15258_1 1249627.D779_0714 1.55e-36 133.0 COG0451@1|root,COG0451@2|Bacteria,1MUGT@1224|Proteobacteria,1RMPQ@1236|Gammaproteobacteria,1WVWB@135613|Chromatiales 135613|Chromatiales GM Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction fcl - 1.1.1.271 ko:K02377 ko00051,ko00520,ko01100,map00051,map00520,map01100 - R05692 RC01014 ko00000,ko00001,ko01000 - - - Epimerase k141_8066_1 394221.Mmar10_2649 6.26e-64 216.0 COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,2TSGE@28211|Alphaproteobacteria,43WYB@69657|Hyphomonadaceae 28211|Alphaproteobacteria S COG0457 FOG TPR repeat - - - - - - - - - - - - Sulfotransfer_3,TPR_16,TPR_19,TPR_2,TPR_8 k141_29709_1 218284.CCDN010000005_gene3299 6.99e-86 261.0 COG0564@1|root,COG0564@2|Bacteria,1TS1T@1239|Firmicutes,4HBRY@91061|Bacilli,1ZB25@1386|Bacillus 91061|Bacilli J Responsible for synthesis of pseudouridine from uracil rluD GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23,5.4.99.28,5.4.99.29 ko:K06177,ko:K06180 - - - - ko00000,ko01000,ko03009,ko03016 - - - PseudoU_synth_2 k141_28258_1 616991.JPOO01000001_gene2777 3.46e-28 109.0 COG5523@1|root,COG5523@2|Bacteria,4NM5R@976|Bacteroidetes,1I1R0@117743|Flavobacteriia 976|Bacteroidetes S integral membrane protein - - - - - - - - - - - - DUF975 k141_28258_2 443143.GM18_3841 1.24e-27 106.0 COG0500@1|root,COG2226@2|Bacteria,1RANW@1224|Proteobacteria,42RZ7@68525|delta/epsilon subdivisions,2WNYJ@28221|Deltaproteobacteria,43UNB@69541|Desulfuromonadales 28221|Deltaproteobacteria Q ubiE/COQ5 methyltransferase family - - - - - - - - - - - - Methyltransf_11 k141_31694_1 1294265.JCM21738_26 4.69e-104 310.0 COG0213@1|root,COG0213@2|Bacteria,1TPCH@1239|Firmicutes,4H9NP@91061|Bacilli,1ZBI1@1386|Bacillus 91061|Bacilli F phosphorylase pdp GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464 2.4.2.2 ko:K00756 ko00240,ko01100,map00240,map01100 - R01570,R01876,R02296,R02484 RC00063 ko00000,ko00001,ko01000 - - - Glycos_trans_3N,Glycos_transf_3,PYNP_C k141_34423_2 1121875.KB907551_gene1026 5.42e-05 44.7 COG0042@1|root,COG0042@2|Bacteria,4NEN4@976|Bacteroidetes,1HWK5@117743|Flavobacteriia 976|Bacteroidetes J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines dus - - - - - - - - - - - Dus k141_21214_1 1279017.AQYJ01000026_gene229 7.08e-222 616.0 COG0334@1|root,COG0334@2|Bacteria,1MUXS@1224|Proteobacteria,1RQ0T@1236|Gammaproteobacteria,4648M@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the Glu Leu Phe Val dehydrogenases family ldh - 1.4.1.9 ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 - R01088,R01434,R02196 RC00006,RC00036 ko00000,ko00001,ko01000 - - - ELFV_dehydrog,ELFV_dehydrog_N k141_37839_1 1042377.AFPJ01000030_gene442 1.73e-60 206.0 COG3240@1|root,COG3240@2|Bacteria,1RCCU@1224|Proteobacteria,1S2GX@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Phospholipase lecithinase hemolysin estA GO:0003674,GO:0003824,GO:0016289,GO:0016290,GO:0016787,GO:0016788,GO:0016790,GO:0047617,GO:0052689 - ko:K12686 - - - - ko00000,ko02000,ko02044 1.B.12.8 - - Autotransporter,Lipase_GDSL k141_37839_2 1453501.JELR01000002_gene124 0.0 1091.0 COG1292@1|root,COG1292@2|Bacteria,1MV0K@1224|Proteobacteria,1RP3E@1236|Gammaproteobacteria,464CV@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the BCCT transporter (TC 2.A.15) family betT - - ko:K02168 - - - - ko00000,ko02000 2.A.15.1.3,2.A.15.1.4 - - BCCT k141_37839_3 1453501.JELR01000002_gene123 0.0 1051.0 COG1292@1|root,COG1292@2|Bacteria,1MV0K@1224|Proteobacteria,1RP3E@1236|Gammaproteobacteria,464CV@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the BCCT transporter (TC 2.A.15) family betT - - ko:K02168 - - - - ko00000,ko02000 2.A.15.1.3,2.A.15.1.4 - - BCCT k141_3714_1 235909.GK2577 1.73e-72 220.0 COG1490@1|root,COG1490@2|Bacteria,1V6GH@1239|Firmicutes,4HINN@91061|Bacilli,1WGCQ@129337|Geobacillus 91061|Bacilli J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality dtd GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - ko:K07560 - - - - ko00000,ko01000,ko03016 - - - Tyr_Deacylase k141_3714_2 218284.CCDN010000001_gene667 5.37e-287 799.0 COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,4HBX7@91061|Bacilli,1ZBN6@1386|Bacillus 91061|Bacilli KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance relA GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5 ko:K00951 ko00230,map00230 - R00429 RC00002,RC00078 ko00000,ko00001,ko01000 - - iYO844.BSU27600 ACT_4,HD_4,RelA_SpoT,TGS k141_9619_1 223926.28807527 3.27e-42 137.0 COG3024@1|root,COG3024@2|Bacteria,1NGJ8@1224|Proteobacteria,1SC7M@1236|Gammaproteobacteria,1XYEN@135623|Vibrionales 135623|Vibrionales S Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase yacG - - ko:K09862 - - - - ko00000 - - - YacG k141_14412_1 42565.FP66_06355 7.29e-140 397.0 COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,1RMX1@1236|Gammaproteobacteria,1XHNR@135619|Oceanospirillales 135619|Oceanospirillales E ABC transporter - - - ko:K09972 ko02010,map02010 M00232 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3.17,3.A.1.3.18,3.A.1.3.7,3.A.1.3.8 - - ABC_tran k141_6107_2 42565.FP66_01910 5.76e-29 113.0 COG2895@1|root,COG2895@2|Bacteria,1MUD9@1224|Proteobacteria,1RME4@1236|Gammaproteobacteria,1XH42@135619|Oceanospirillales 135619|Oceanospirillales P Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily cysN - 2.7.1.25,2.7.7.4 ko:K00955,ko:K00956 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176,M00596 R00509,R00529,R04928,R04929 RC00002,RC00078,RC02809,RC02889 ko00000,ko00001,ko00002,ko01000 - - - GTP_EFTU,GTP_EFTU_D3 k141_27437_1 1385510.N781_14475 3.95e-25 97.4 COG3224@1|root,COG3224@2|Bacteria,1V83H@1239|Firmicutes,4HJC6@91061|Bacilli,2YAP8@289201|Pontibacillus 91061|Bacilli S Ethyl tert-butyl ether degradation protein EthD ethD - - - - - - - - - - - EthD k141_27437_2 1280390.CBQR020000140_gene3444 6.86e-14 70.5 COG1028@1|root,COG1028@2|Bacteria,1TRQB@1239|Firmicutes,4HUJ4@91061|Bacilli,272AZ@186822|Paenibacillaceae 91061|Bacilli IQ KR domain - - - - - - - - - - - - adh_short k141_10792_1 218284.CCDN010000006_gene3729 2.24e-168 494.0 COG0737@1|root,COG2247@1|root,COG0737@2|Bacteria,COG2247@2|Bacteria,1TPV2@1239|Firmicutes,4H9VJ@91061|Bacilli,1ZS4T@1386|Bacillus 91061|Bacilli F COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases cpdB - 3.1.3.5,3.1.3.6,3.1.4.16,3.6.1.45 ko:K01081,ko:K07004,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01562,R01569,R01664,R01877,R01968,R02088,R02102,R02148,R02323,R02370,R02719,R03346,R03537,R03538,R03929,R05135 RC00017,RC00078,RC00296 ko00000,ko00001,ko01000 - - - 5_nucleotid_C,CHB_HEX_C_1,Gram_pos_anchor,LTD,Metallophos,SLH k141_1250_1 218284.CCDN010000010_gene4373 1.68e-199 585.0 COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,4HA24@91061|Bacilli,1ZDK0@1386|Bacillus 91061|Bacilli K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoC GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 k141_16750_2 1453501.JELR01000005_gene1585 6.45e-47 158.0 COG0837@1|root,COG0837@2|Bacteria,1MVFI@1224|Proteobacteria,1RNUY@1236|Gammaproteobacteria,464W6@72275|Alteromonadaceae 1236|Gammaproteobacteria F Belongs to the bacterial glucokinase family glk - 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Glucokinase k141_12002_1 6500.XP_005092325.1 1.67e-66 212.0 COG1171@1|root,KOG1251@2759|Eukaryota,3AJVW@33154|Opisthokonta,3BZSW@33208|Metazoa,3DG6W@33213|Bilateria 33208|Metazoa ET Pyridoxal-phosphate dependent enzyme - - - - - - - - - - - - PALP k141_21568_1 1185876.BN8_02675 7.46e-75 251.0 COG0784@1|root,COG3604@1|root,COG0784@2|Bacteria,COG3604@2|Bacteria,4PMAT@976|Bacteroidetes,47Y62@768503|Cytophagia 976|Bacteroidetes T Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - ko:K02584 ko02020,map02020 - - - ko00000,ko00001,ko03000 - - - GAF,GAF_2,GAF_3,HTH_8,PAS_9,Response_reg,Sigma54_activat k141_34611_1 935836.JAEL01000003_gene390 3.9e-89 266.0 COG1238@1|root,COG1238@2|Bacteria,1V63I@1239|Firmicutes,4HHHW@91061|Bacilli,1ZQK4@1386|Bacillus 91061|Bacilli S SNARE associated Golgi protein - - - - - - - - - - - - SNARE_assoc k141_31062_1 42565.FP66_10525 1.67e-87 268.0 2DC1M@1|root,2ZCGD@2|Bacteria,1RC49@1224|Proteobacteria 1224|Proteobacteria S Alginate lyase - - 4.2.2.3 ko:K01729 ko00051,map00051 - R03706 - ko00000,ko00001,ko01000 - - - Alginate_lyase k141_25062_1 1216362.B437_07082 4.51e-08 60.5 COG0202@1|root,COG0202@2|Bacteria,3791W@32066|Fusobacteria 32066|Fusobacteria K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoA GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L k141_22732_1 218284.CCDN010000002_gene2941 4.02e-136 399.0 COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,4HAM7@91061|Bacilli,1ZBG8@1386|Bacillus 91061|Bacilli E COG0747 ABC-type dipeptide transport system, periplasmic component dppA - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 k141_28693_2 1121127.JAFA01000019_gene600 1.05e-06 54.7 COG0583@1|root,COG0583@2|Bacteria,1QVP2@1224|Proteobacteria,2VZTA@28216|Betaproteobacteria,1K6QC@119060|Burkholderiaceae 28216|Betaproteobacteria K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate k141_32187_1 945543.VIBR0546_15336 1.74e-86 268.0 COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,1MUV9@1224|Proteobacteria,1RN8U@1236|Gammaproteobacteria,1XT4K@135623|Vibrionales 135623|Vibrionales C Catalyzes the reversible hydration of fumarate to (S)- malate fumA - 4.2.1.2 ko:K01676 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - - Fumerase,Fumerase_C k141_32187_2 1280001.BAOA01000004_gene3742 2.26e-23 90.1 29VTS@1|root,30HBD@2|Bacteria,1QTBG@1224|Proteobacteria,1TIE4@1236|Gammaproteobacteria,1XYYM@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_32187_3 1116375.VEJY3_09955 4.51e-158 453.0 COG3106@1|root,COG3106@2|Bacteria,1MX6E@1224|Proteobacteria,1RQ05@1236|Gammaproteobacteria,1XT2C@135623|Vibrionales 135623|Vibrionales S YcjX-like family, DUF463 ycjX - - ko:K06918 - - - - ko00000 - - - DUF463 k141_2523_1 426114.THI_0746 5.5e-33 118.0 COG4969@1|root,COG4969@2|Bacteria,1N7EQ@1224|Proteobacteria,2VVSJ@28216|Betaproteobacteria,1KMGT@119065|unclassified Burkholderiales 28216|Betaproteobacteria NU Belongs to the N-Me-Phe pilin family pilA - - ko:K02650 ko02020,map02020 - - - ko00000,ko00001,ko02035,ko02044 3.A.15.2 - - N_methyl,Pilin k141_14413_2 1117379.BABA_07396 3.91e-55 175.0 COG4922@1|root,COG4922@2|Bacteria,1V6S2@1239|Firmicutes,4HJRI@91061|Bacilli,1ZGJ4@1386|Bacillus 91061|Bacilli S SnoaL-like domain - - - - - - - - - - - - SnoaL,SnoaL_2 k141_14413_3 1131730.BAVI_18707 2.82e-27 103.0 2DN7T@1|root,32W0M@2|Bacteria,1VCUR@1239|Firmicutes,4HKRJ@91061|Bacilli,1ZIP8@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_27438_1 218284.CCDN010000002_gene2730 2.16e-76 247.0 COG2213@1|root,COG4668@1|root,COG2213@2|Bacteria,COG4668@2|Bacteria,1TPE3@1239|Firmicutes,4HAVV@91061|Bacilli,1ZC81@1386|Bacillus 91061|Bacilli G COG2213 Phosphotransferase system, mannitol-specific IIBC component mtlA - 2.7.1.197 ko:K02798,ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 M00274 R02704 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1.12,4.A.2.1.2,4.A.2.1.24,4.A.2.1.5 - - PTS_EIIA_2,PTS_EIIC,PTS_IIB k141_33400_1 218284.CCDN010000003_gene2962 1.22e-132 393.0 COG1982@1|root,COG1982@2|Bacteria,1TNZ9@1239|Firmicutes,4HBGC@91061|Bacilli,1ZBKS@1386|Bacillus 91061|Bacilli E Orn Lys Arg decarboxylase yaaO - - - - - - - - - - - OKR_DC_1,OKR_DC_1_C k141_175_1 1379270.AUXF01000001_gene2161 8.39e-101 326.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG1146@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,COG1146@2|Bacteria 2|Bacteria C 4 iron, 4 sulfur cluster binding nifJ - 1.2.7.1 ko:K03737 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00173,M00307 R01196,R10866 RC00004,RC02742 br01601,ko00000,ko00001,ko00002,ko01000 - - - EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C k141_10793_1 1307436.PBF_15149 2.21e-75 240.0 COG1113@1|root,COG1113@2|Bacteria,1TP97@1239|Firmicutes,4H9QX@91061|Bacilli,1ZDGG@1386|Bacillus 91061|Bacilli E COG1113 Gamma-aminobutyrate permease and related permeases ycgH GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03293 - - - - ko00000 2.A.3.1 - - AA_permease k141_9621_1 999141.GME_17072 3.33e-98 302.0 COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,1RMGP@1236|Gammaproteobacteria,1XN2E@135619|Oceanospirillales 135619|Oceanospirillales C C-terminal domain of alpha-glycerophosphate oxidase - - 1.1.5.3 ko:K00111 ko00564,ko01110,map00564,map01110 - R00848 RC00029 ko00000,ko00001,ko01000 - - - DAO,DAO_C k141_36945_2 1453501.JELR01000001_gene2001 1.82e-14 71.2 COG2084@1|root,COG2084@2|Bacteria,1MUGU@1224|Proteobacteria,1RQ2D@1236|Gammaproteobacteria,464XV@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases garR - 1.1.1.31,1.1.1.60 ko:K00020,ko:K00042 ko00280,ko00630,ko01100,map00280,map00630,map01100 - R01745,R01747,R05066 RC00099 ko00000,ko00001,ko01000 - - - NAD_binding_11,NAD_binding_2 k141_4878_1 1042377.AFPJ01000024_gene819 4.43e-186 527.0 COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,1RN0W@1236|Gammaproteobacteria,464SX@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0006 Xaa-Pro aminopeptidase pepP - 3.4.11.9 ko:K01262 - - - - ko00000,ko01000,ko01002 - - - AMP_N,Peptidase_M24 k141_4878_2 1453501.JELR01000002_gene699 1.99e-60 193.0 COG3079@1|root,COG3079@2|Bacteria,1N7W0@1224|Proteobacteria,1SCPW@1236|Gammaproteobacteria,4689M@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the UPF0149 family ygfB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K09895 - - - - ko00000 - - - UPF0149 k141_4878_3 1279017.AQYJ01000028_gene2160 2.77e-31 110.0 2C0ET@1|root,33A9M@2|Bacteria,1NGE5@1224|Proteobacteria,1SGID@1236|Gammaproteobacteria,4697N@72275|Alteromonadaceae 1236|Gammaproteobacteria S TIGRFAM TIGR02449 family protein VL23_04670 - - ko:K09892 - - - - ko00000,ko03036 - - - - k141_4878_4 1279017.AQYJ01000028_gene2159 2.88e-45 149.0 COG3027@1|root,COG3027@2|Bacteria,1N6YN@1224|Proteobacteria,1SCBI@1236|Gammaproteobacteria,468PG@72275|Alteromonadaceae 1236|Gammaproteobacteria D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division zapA GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000921,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0030428,GO:0031106,GO:0032153,GO:0032185,GO:0032505,GO:0032506,GO:0034622,GO:0042802,GO:0043093,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0051301,GO:0061640,GO:0065003,GO:0070925,GO:0071840,GO:0090529,GO:1902410,GO:1903047 - ko:K09888 - - - - ko00000,ko03036 - - - ZapA k141_4878_5 1279017.AQYJ01000028_gene2158 2.03e-85 258.0 COG0212@1|root,COG0212@2|Bacteria,1MZG0@1224|Proteobacteria,1S612@1236|Gammaproteobacteria,467AN@72275|Alteromonadaceae 1236|Gammaproteobacteria H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family ygfA GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0022611,GO:0030272,GO:0032502,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.2 ko:K01934 ko00670,ko01100,map00670,map01100 - R02301 RC00183 ko00000,ko00001,ko01000 - - iECABU_c1320.ECABU_c31940,iECOK1_1307.ECOK1_3298,iECSF_1327.ECSF_2705,iUTI89_1310.UTI89_C3298 5-FTHF_cyc-lig k141_15619_1 1122194.AUHU01000002_gene2466 1.17e-92 303.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MV8W@1224|Proteobacteria,1RMQA@1236|Gammaproteobacteria,469JF@72275|Alteromonadaceae 1236|Gammaproteobacteria P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec k141_32188_2 997346.HMPREF9374_3148 7.09e-68 214.0 COG0572@1|root,COG0572@2|Bacteria,1TQ4V@1239|Firmicutes,4HAVR@91061|Bacilli,27AZ4@186824|Thermoactinomycetaceae 91061|Bacilli F Phosphoribulokinase / Uridine kinase family udk GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.48 ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PRK k141_32188_3 101510.RHA1_ro05444 0.000794 40.8 COG1089@1|root,COG1089@2|Bacteria,2GNMA@201174|Actinobacteria,4FYKP@85025|Nocardiaceae 201174|Actinobacteria M Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose gmd - 4.2.1.47 ko:K01711 ko00051,ko00520,ko01100,map00051,map00520,map01100 - R00888 RC00402 ko00000,ko00001,ko01000 - - - GDP_Man_Dehyd k141_16752_2 218284.CCDN010000010_gene4342 6.15e-46 147.0 COG0361@1|root,COG0361@2|Bacteria,1V9ZK@1239|Firmicutes,4HKF4@91061|Bacilli,1ZHWN@1386|Bacillus 91061|Bacilli J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex infA GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - ko:K02518 - - - - ko00000,ko03012 - - - eIF-1a k141_12004_1 218284.CCDN010000001_gene90 3.64e-138 412.0 COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,4H9VQ@91061|Bacilli,1ZASE@1386|Bacillus 91061|Bacilli M Penicillin-binding Protein pbpX GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - - PASTA,PBP_dimer,Transpeptidase k141_6108_1 1042377.AFPJ01000037_gene2997 5.42e-144 412.0 COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,1RMGN@1236|Gammaproteobacteria,463XZ@72275|Alteromonadaceae 1236|Gammaproteobacteria E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate trpA - 4.2.1.20 ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - Trp_syntA k141_6108_2 1279017.AQYJ01000021_gene2896 1.08e-187 523.0 COG0777@1|root,COG0777@2|Bacteria,1MW8G@1224|Proteobacteria,1RNDS@1236|Gammaproteobacteria,4649N@72275|Alteromonadaceae 1236|Gammaproteobacteria I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA accD GO:0001676,GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003729,GO:0003824,GO:0003989,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006417,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0009058,GO:0009317,GO:0009329,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0017148,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032787,GO:0032991,GO:0034248,GO:0034249,GO:0042759,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:0097159,GO:1901363,GO:1901576,GO:1902494,GO:1990234,GO:2000112,GO:2000113 2.1.3.15,6.4.1.2 ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - iPC815.YPO2768,iUTI89_1310.UTI89_C2601 Carboxyl_trans k141_25063_1 1423321.AS29_04775 0.000618 47.4 COG2311@1|root,COG2311@2|Bacteria,1TQNS@1239|Firmicutes,4HCR3@91061|Bacilli,1ZBX3@1386|Bacillus 91061|Bacilli P Protein of unknown function (DUF418) yrkO - - ko:K07148 - - - - ko00000 - - - DUF418 k141_20313_1 55601.VANGNB10_cI1793c 6.6e-162 459.0 COG0583@1|root,COG0583@2|Bacteria,1MW1R@1224|Proteobacteria,1RQMP@1236|Gammaproteobacteria,1XUU4@135623|Vibrionales 135623|Vibrionales K Transcriptional regulator, LysR family - - - - - - - - - - - - HTH_1,LysR_substrate k141_4892_1 1294265.JCM21738_517 9.2e-114 331.0 COG1366@1|root,COG1366@2|Bacteria,1V6ME@1239|Firmicutes,4HJGU@91061|Bacilli,1ZCN1@1386|Bacillus 91061|Bacilli T STAS domain - - - ko:K17763 - - - - ko00000,ko03021 - - - STAS k141_1284_1 1042377.AFPJ01000036_gene1287 2.28e-115 348.0 COG0304@1|root,COG0304@2|Bacteria,1MV67@1224|Proteobacteria,1RMXJ@1236|Gammaproteobacteria,4660E@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ Beta-ketoacyl synthase, C-terminal domain - - 2.3.1.180 ko:K18473 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt k141_6150_1 316274.Haur_0288 5.31e-42 157.0 COG1200@1|root,COG1200@2|Bacteria,2G5YM@200795|Chloroflexi,3753C@32061|Chloroflexia 32061|Chloroflexia L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) recG - 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecG_wedge k141_3746_1 218284.CCDN010000001_gene592 5.14e-76 232.0 COG2102@1|root,COG2102@2|Bacteria,1V5NH@1239|Firmicutes,4HID4@91061|Bacilli,1ZDP8@1386|Bacillus 91061|Bacilli S Diphthamide synthase - - - - - - - - - - - - Diphthami_syn_2 k141_33406_1 1042377.AFPJ01000009_gene265 3.54e-88 269.0 COG1680@1|root,COG1680@2|Bacteria,1QD0J@1224|Proteobacteria,1RZUZ@1236|Gammaproteobacteria,46CRC@72275|Alteromonadaceae 1236|Gammaproteobacteria V Beta-lactamase estC - - - - - - - - - - - Beta-lactamase k141_213_1 218284.CCDN010000002_gene2116 0.0 926.0 COG0129@1|root,COG0129@2|Bacteria,1TP1R@1239|Firmicutes,4H9ZG@91061|Bacilli,1ZASK@1386|Bacillus 91061|Bacilli E Belongs to the IlvD Edd family ilvD - 4.2.1.9 ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 M00019,M00570,M00582 R01209,R04441,R05070 RC00468,RC01714 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ILVD_EDD k141_34631_1 218284.CCDN010000005_gene3184 2.2e-115 341.0 COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,4H9WQ@91061|Bacilli,1ZAR7@1386|Bacillus 91061|Bacilli E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase yhaA - - ko:K01436 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 k141_1285_2 1308866.J416_07627 3.38e-15 75.9 COG4508@1|root,COG4508@2|Bacteria,1V6PI@1239|Firmicutes,4HJBB@91061|Bacilli,470PP@74385|Gracilibacillus 91061|Bacilli S dUTPase - - - - - - - - - - - - dUTPase_2 k141_23891_1 1191299.AJYX01000056_gene2726 2.79e-38 132.0 2DTB0@1|root,33JH6@2|Bacteria,1NPKK@1224|Proteobacteria,1SJBY@1236|Gammaproteobacteria,1XY5Y@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_6151_1 1236959.BAMT01000001_gene1588 2.3e-10 67.0 COG4773@1|root,COG4773@2|Bacteria,1QTXJ@1224|Proteobacteria,2VPMU@28216|Betaproteobacteria,2KKDY@206350|Nitrosomonadales 206350|Nitrosomonadales P TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_13256_1 218284.CCDN010000010_gene4369 8.24e-194 554.0 COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,4HAB8@91061|Bacilli,1ZBS4@1386|Bacillus 91061|Bacilli J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome fusA - - ko:K02355 - - - - ko00000,ko03012,ko03029 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 k141_28723_1 1453501.JELR01000001_gene3103 6.2e-168 475.0 COG0656@1|root,COG0656@2|Bacteria,1MX6S@1224|Proteobacteria,1RQA1@1236|Gammaproteobacteria,466RA@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0656 Aldo keto reductases, related to diketogulonate reductase - - - - - - - - - - - - Aldo_ket_red k141_36966_1 218284.CCDN010000005_gene3192 2.28e-153 436.0 COG0407@1|root,COG0407@2|Bacteria,1TR8Q@1239|Firmicutes,4HAXT@91061|Bacilli,1ZDGX@1386|Bacillus 91061|Bacilli H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III hemE GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03197,R04972 RC00872 ko00000,ko00001,ko00002,ko01000 - - - URO-D k141_36966_2 218284.CCDN010000005_gene3191 4.11e-83 248.0 COG2329@1|root,COG2329@2|Bacteria,1V501@1239|Firmicutes,4HHA2@91061|Bacilli,1ZGDD@1386|Bacillus 91061|Bacilli S enzyme involved in biosynthesis of extracellular polysaccharides traP GO:0005575,GO:0016020 1.14.99.57 ko:K21481 - - - - ko00000,ko01000 - - - ABM k141_14439_1 1121938.AUDY01000011_gene672 5.14e-66 219.0 COG0189@1|root,COG0189@2|Bacteria,1V3RH@1239|Firmicutes 1239|Firmicutes HJ YheC/D like ATP-grasp - - - - - - - - - - - - ATPgrasp_YheCD k141_14439_2 997296.PB1_09652 1.53e-44 158.0 COG0151@1|root,COG0151@2|Bacteria,1UR8C@1239|Firmicutes,4IS9W@91061|Bacilli,1ZF4M@1386|Bacillus 91061|Bacilli F Biotin carboxylase - - - - - - - - - - - - ATP-grasp_4 k141_10807_1 1453501.JELR01000002_gene342 2.36e-242 779.0 COG1361@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4932@2|Bacteria,1R5G4@1224|Proteobacteria,1SEWA@1236|Gammaproteobacteria,469S7@72275|Alteromonadaceae 1236|Gammaproteobacteria M Domain of unknown function DUF11 - - - - - - - - - - - - DUF11,SdrD_B k141_18036_2 1116375.VEJY3_13560 5.99e-228 631.0 COG0795@1|root,COG0795@2|Bacteria,1MVW3@1224|Proteobacteria,1RM8H@1236|Gammaproteobacteria,1XTBS@135623|Vibrionales 135623|Vibrionales S Predicted permease YjgP/YjgQ family lptG - - ko:K11720 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko02000 1.B.42.1 - - YjgP_YjgQ k141_18036_3 223926.28807653 1.45e-240 664.0 COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,1RMN5@1236|Gammaproteobacteria,1XSK9@135623|Vibrionales 135623|Vibrionales S Predicted permease YjgP/YjgQ family lptF - - ko:K07091 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko02000 1.B.42.1 - - YjgP_YjgQ k141_18036_4 1219077.VAZ01S_026_00720 0.0 917.0 COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,1RNM1@1236|Gammaproteobacteria,1XT1U@135623|Vibrionales 135623|Vibrionales E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides pepA - 3.4.11.1 ko:K01255 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - Peptidase_M17,Peptidase_M17_N k141_19146_2 218284.CCDN010000007_gene3874 2.07e-12 66.2 COG0714@1|root,COG0714@2|Bacteria,1V1P5@1239|Firmicutes,4HG3W@91061|Bacilli,1ZBKT@1386|Bacillus 91061|Bacilli S ATPase family associated with various cellular activities (AAA) gvpN - - - - - - - - - - - AAA_5 k141_16787_2 1357275.AVEL02000125_gene3523 9.33e-37 144.0 COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,1RNAZ@1236|Gammaproteobacteria,1Z5AZ@136849|Pseudomonas syringae group 1236|Gammaproteobacteria L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseA GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494 3.1.11.6 ko:K03601 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_L,tRNA_anti_2 k141_35767_2 1279017.AQYJ01000025_gene579 1.24e-294 811.0 COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,464D8@72275|Alteromonadaceae 1236|Gammaproteobacteria NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB gspE - - ko:K02454 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSE,T2SSE_N k141_22742_1 218284.CCDN010000001_gene1150 3.65e-158 474.0 COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H9SA@91061|Bacilli,1ZAXY@1386|Bacillus 91061|Bacilli M penicillin-binding protein ponA GO:0005575,GO:0005576 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase k141_14440_1 1234664.AMRO01000031_gene3705 2.1e-43 151.0 COG0476@1|root,COG0476@2|Bacteria,1TQ3U@1239|Firmicutes,4HBGP@91061|Bacilli,1WF0N@129337|Geobacillus 91061|Bacilli H Catalyzes the formation of a high-energy acyladenylate intermediate and subsequently to the formation of a thiocarboxylate at the C termini of MoaD or ThiS in the molybdopterin or thiamin pyrophosphate biosynthesis pathways moeB - 2.7.7.73,2.7.7.80 ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07459 RC00043 ko00000,ko00001,ko01000 - - - ThiF k141_14440_2 1444310.JANV01000025_gene3852 5.41e-18 81.3 COG2022@1|root,COG2022@2|Bacteria,1TQZ1@1239|Firmicutes,4HBSI@91061|Bacilli,1ZB9S@1386|Bacillus 91061|Bacilli H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S thiG GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 ko:K03149 ko00730,ko01100,map00730,map01100 - R10247 RC03096,RC03097,RC03461 ko00000,ko00001,ko01000 - - - ThiG k141_21591_2 1313172.YM304_32080 2.11e-65 210.0 COG0110@1|root,COG0110@2|Bacteria 2|Bacteria S O-acyltransferase activity - - - - - - - - - - - - Hexapep k141_13257_1 1033810.HLPCO_002893 2.04e-08 57.0 2CS58@1|root,32SQC@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k141_34632_1 1279017.AQYJ01000028_gene2061 2.41e-69 229.0 COG3064@1|root,COG3064@2|Bacteria,1RINZ@1224|Proteobacteria,1S7TN@1236|Gammaproteobacteria,4692U@72275|Alteromonadaceae 1236|Gammaproteobacteria M Domain of unknown function (DUF4350) - - - - - - - - - - - - DUF4350 k141_34632_2 1179778.PMM47T1_02514 6.8e-10 60.8 COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,1RN5G@1236|Gammaproteobacteria 1236|Gammaproteobacteria S PFAM ATPase associated with various cellular activities - - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 k141_26341_1 1116375.VEJY3_09940 2.41e-121 348.0 COG1670@1|root,COG1670@2|Bacteria,1MVG4@1224|Proteobacteria,1RQPX@1236|Gammaproteobacteria,1XV1R@135623|Vibrionales 135623|Vibrionales J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins rimJ - 2.3.1.128 ko:K03790 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 k141_26341_2 1116375.VEJY3_09945 0.0 971.0 COG3283@1|root,COG3283@2|Bacteria,1QTS3@1224|Proteobacteria,1RNAI@1236|Gammaproteobacteria,1XSF4@135623|Vibrionales 135623|Vibrionales K COG3283 Transcriptional regulator of aromatic amino acids metabolism tyrR - - ko:K03721 - - - - ko00000,ko03000 - - - PAS,PAS_8,Sigma54_activat k141_26341_3 223926.28806862 4.67e-197 552.0 COG3768@1|root,COG3768@2|Bacteria,1MU8S@1224|Proteobacteria,1RND9@1236|Gammaproteobacteria,1XSBZ@135623|Vibrionales 135623|Vibrionales S membrane ycjF - - ko:K08990 - - - - ko00000 - - - DUF697 k141_26341_4 1116375.VEJY3_09955 5.14e-243 673.0 COG3106@1|root,COG3106@2|Bacteria,1MX6E@1224|Proteobacteria,1RQ05@1236|Gammaproteobacteria,1XT2C@135623|Vibrionales 135623|Vibrionales S YcjX-like family, DUF463 ycjX - - ko:K06918 - - - - ko00000 - - - DUF463 k141_2555_1 218284.CCDN010000007_gene3908 1.16e-18 84.0 COG3314@1|root,COG3314@2|Bacteria,1TR35@1239|Firmicutes,4HAB6@91061|Bacilli,1ZARZ@1386|Bacillus 91061|Bacilli S protein conserved in bacteria - - - - - - - - - - - - Gate k141_36967_1 218284.CCDN010000001_gene1939 2.27e-108 328.0 COG4988@1|root,COG4988@2|Bacteria,1TQ1P@1239|Firmicutes,4HAN0@91061|Bacilli,1ZB86@1386|Bacillus 91061|Bacilli V ATP-binding cydD - - ko:K06148,ko:K16013 ko02010,map02010 - - - ko00000,ko00001,ko02000 3.A.1,3.A.1.129 - - ABC_membrane,ABC_tran k141_3749_2 218284.CCDN010000001_gene600 8.53e-166 473.0 COG0373@1|root,COG0373@2|Bacteria,1TQN9@1239|Firmicutes,4HAVC@91061|Bacilli,1ZBER@1386|Bacillus 91061|Bacilli H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) hemA - 1.2.1.70 ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R04109 RC00055,RC00149 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS08420 GlutR_N,GlutR_dimer,Shikimate_DH k141_15644_4 563192.HMPREF0179_03259 5.15e-75 234.0 COG3617@1|root,COG3645@1|root,COG3617@2|Bacteria,COG3645@2|Bacteria,1N09A@1224|Proteobacteria,42UII@68525|delta/epsilon subdivisions,2X6ME@28221|Deltaproteobacteria,2MH4F@213115|Desulfovibrionales 28221|Deltaproteobacteria K Phage antirepressor protein KilAC domain - - - - - - - - - - - - ANT,Bro-N k141_35768_1 1279017.AQYJ01000022_gene2726 2.97e-34 137.0 COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,1RMIA@1236|Gammaproteobacteria,464IG@72275|Alteromonadaceae 1236|Gammaproteobacteria L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity dnaX GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030234,GO:0030337,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0042802,GO:0043170,GO:0043846,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050790,GO:0061695,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0098772,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNA_pol3_gamma3,DNA_pol3_tau_4,DNA_pol3_tau_5 k141_13499_2 1042377.AFPJ01000007_gene1747 3.27e-16 75.9 COG1309@1|root,COG1309@2|Bacteria,1NM93@1224|Proteobacteria,1S56I@1236|Gammaproteobacteria,46DG9@72275|Alteromonadaceae 1236|Gammaproteobacteria K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N k141_31259_1 674977.VMC_15520 2.54e-20 89.4 COG3104@1|root,COG3104@2|Bacteria,1MW6W@1224|Proteobacteria,1RM8P@1236|Gammaproteobacteria,1XTDG@135623|Vibrionales 135623|Vibrionales U COG3104 Dipeptide tripeptide permease - - - ko:K03305 - - - - ko00000 2.A.17 - - PTR2 k141_31259_2 1116375.VEJY3_03740 7.97e-224 617.0 COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,1RMMS@1236|Gammaproteobacteria,1XUVQ@135623|Vibrionales 135623|Vibrionales H Catalyzes the ferrous insertion into protoporphyrin IX hemH GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R00310,R11329 RC01012 ko00000,ko00001,ko00002,ko01000 - - - Ferrochelatase k141_31259_3 945550.VISI1226_05521 3.28e-145 410.0 COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,1RMT6@1236|Gammaproteobacteria,1XT6A@135623|Vibrionales 135623|Vibrionales F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism adk GO:0003674,GO:0003824,GO:0004017,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ADK,ADK_lid k141_31259_4 223926.28805807 0.0 1186.0 COG0326@1|root,COG0326@2|Bacteria,1MUUE@1224|Proteobacteria,1RNWD@1236|Gammaproteobacteria,1XSVC@135623|Vibrionales 135623|Vibrionales O Molecular chaperone. Has ATPase activity htpG GO:0006457,GO:0008150,GO:0009987 - ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 - - - ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 - - - HATPase_c,HATPase_c_3,HSP90 k141_31259_5 674977.VMC_40510 8.04e-138 398.0 COG3710@1|root,COG3710@2|Bacteria,1QXRC@1224|Proteobacteria,1SDUS@1236|Gammaproteobacteria,1XUD7@135623|Vibrionales 135623|Vibrionales K COG3710 DNA-binding winged-HTH domains toxR GO:0000156,GO:0000160,GO:0003674,GO:0006355,GO:0007154,GO:0007165,GO:0008150,GO:0009405,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0023052,GO:0031323,GO:0031326,GO:0035556,GO:0044419,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051704,GO:0051716,GO:0060089,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K10921 ko05111,map05111 - - - ko00000,ko00001 - - - Trans_reg_C k141_31259_6 1116375.VEJY3_03720 2.9e-102 298.0 2AVZE@1|root,31MTT@2|Bacteria,1QJJZ@1224|Proteobacteria,1THKE@1236|Gammaproteobacteria,1XWII@135623|Vibrionales 135623|Vibrionales S Trans-membrane regulatory protein ToxS toxS GO:0005575,GO:0005623,GO:0005886,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0016020,GO:0023052,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071944 - ko:K10922 ko05111,map05111 - - - ko00000,ko00001 - - - ToxS k141_31259_7 1116375.VEJY3_03715 9.92e-163 457.0 COG0730@1|root,COG0730@2|Bacteria,1QJA6@1224|Proteobacteria,1TH8V@1236|Gammaproteobacteria,1XSJS@135623|Vibrionales 135623|Vibrionales S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE k141_31259_8 223926.28805803 3.46e-61 187.0 COG3526@1|root,COG3526@2|Bacteria,1MZ5V@1224|Proteobacteria,1S8S8@1236|Gammaproteobacteria,1XXYR@135623|Vibrionales 135623|Vibrionales O selenoprotein W-related protein - - - ko:K07401 - - - - ko00000 - - - Rdx k141_31259_9 1116375.VEJY3_03705 1.22e-117 337.0 COG0622@1|root,COG0622@2|Bacteria,1R3Y7@1224|Proteobacteria,1RY3X@1236|Gammaproteobacteria,1XT08@135623|Vibrionales 135623|Vibrionales S Phosphoesterase yfcE - - ko:K07095 - - - - ko00000 - - - Metallophos_2 k141_31259_10 223926.28805801 1.06e-38 129.0 2AWMI@1|root,31NI9@2|Bacteria,1QK8Z@1224|Proteobacteria,1TICE@1236|Gammaproteobacteria,1XYV8@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_31259_11 1116375.VEJY3_03695 1.35e-80 239.0 COG2905@1|root,COG2905@2|Bacteria,1MZGY@1224|Proteobacteria,1S86K@1236|Gammaproteobacteria,1XXFK@135623|Vibrionales 135623|Vibrionales T COG0517 FOG CBS domain - - - - - - - - - - - - CBS k141_31259_12 1116375.VEJY3_03690 9.87e-70 211.0 COG0347@1|root,COG0347@2|Bacteria,1RI28@1224|Proteobacteria,1S62Z@1236|Gammaproteobacteria,1XXA8@135623|Vibrionales 135623|Vibrionales K Belongs to the P(II) protein family VV0993 - - - - - - - - - - - - k141_31259_13 1116375.VEJY3_03685 1.18e-160 453.0 arCOG03638@1|root,2Z8W3@2|Bacteria,1N2PH@1224|Proteobacteria,1RMI8@1236|Gammaproteobacteria,1XUA3@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF1538) - - - - - - - - - - - - DUF1538 k141_31259_14 1219076.N646_2963 1.2e-139 398.0 arCOG03638@1|root,2Z7NN@2|Bacteria,1R3Y6@1224|Proteobacteria,1RTWY@1236|Gammaproteobacteria,1XU34@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF1538) - - - - - - - - - - - - DUF1538 k141_450_1 1453501.JELR01000002_gene465 4.88e-175 507.0 COG1506@1|root,COG1506@2|Bacteria,1P6E1@1224|Proteobacteria,1RPRK@1236|Gammaproteobacteria,464ZW@72275|Alteromonadaceae 1236|Gammaproteobacteria E Dipeptidyl peptidase IV (DPP IV) N-terminal region dpp4 - 3.4.14.5 ko:K01278 ko04974,map04974 - - - ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 - - - DPPIV_N,Peptidase_S9 k141_29976_2 1453501.JELR01000001_gene2871 2.58e-157 451.0 COG0560@1|root,COG0560@2|Bacteria,1MW38@1224|Proteobacteria,1RQAT@1236|Gammaproteobacteria,464CR@72275|Alteromonadaceae 1236|Gammaproteobacteria E haloacid dehalogenase-like hydrolase - - - - - - - - - - - - HAD k141_5109_1 1453501.JELR01000001_gene1956 3.61e-09 56.6 COG0460@1|root,COG0460@2|Bacteria,1MUDC@1224|Proteobacteria,1RPEU@1236|Gammaproteobacteria,463Y5@72275|Alteromonadaceae 1236|Gammaproteobacteria E homoserine dehydrogenase hom - 1.1.1.3,2.7.2.4 ko:K00003,ko:K12524 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00017,M00018,M00526,M00527 R00480,R01773,R01775 RC00002,RC00043,RC00087 ko00000,ko00001,ko00002,ko01000 - - - ACT,Homoserine_dh,NAD_binding_3 k141_13500_1 268407.PWYN_15645 1.28e-77 244.0 COG1783@1|root,COG1783@2|Bacteria,1TRQP@1239|Firmicutes,4HDMY@91061|Bacilli,26WVX@186822|Paenibacillaceae 91061|Bacilli S Terminase RNAseH like domain - - - ko:K06909 - - - - ko00000 - - - Terminase_3,Terminase_3C k141_15806_1 1280001.BAOA01000020_gene365 0.0 951.0 COG4656@1|root,COG4656@2|Bacteria,1QTUI@1224|Proteobacteria,1RMIM@1236|Gammaproteobacteria,1XTPN@135623|Vibrionales 135623|Vibrionales C Part of a membrane complex involved in electron transport rnfC GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0055114 - ko:K03615 - - - - ko00000 - - - Complex1_51K,Fer4,Fer4_10,Fer4_7,RnfC_N,SLBB k141_15806_2 1116375.VEJY3_10920 5.87e-122 350.0 COG2878@1|root,COG2878@2|Bacteria,1MUWU@1224|Proteobacteria,1RNSJ@1236|Gammaproteobacteria,1XSHC@135623|Vibrionales 135623|Vibrionales C Part of a membrane complex involved in electron transport rnfB GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0055114 - ko:K03616 - - - - ko00000 - - - FeS,Fer4_21 k141_15806_3 223926.28807095 4.55e-123 353.0 COG4657@1|root,COG4657@2|Bacteria,1MU8X@1224|Proteobacteria,1RQDN@1236|Gammaproteobacteria,1XSIP@135623|Vibrionales 135623|Vibrionales C Part of a membrane complex involved in electron transport rnfA GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0055114 - ko:K03617 - - - - ko00000 - - - Rnf-Nqr k141_15806_4 314292.VAS14_22007 1.79e-12 71.2 COG2165@1|root,COG2165@2|Bacteria,1P2MH@1224|Proteobacteria,1SRA9@1236|Gammaproteobacteria,1XYS6@135623|Vibrionales 135623|Vibrionales NU Prokaryotic N-terminal methylation motif - - - ko:K10924 ko05111,map05111 - - - ko00000,ko00001,ko02044 - - - N_methyl k141_15806_5 1116375.VEJY3_10910 0.0 1258.0 COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,1RN6Z@1236|Gammaproteobacteria,1XV2Z@135623|Vibrionales 135623|Vibrionales L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage uvrB - - ko:K03702 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - Helicase_C,ResIII,UVR,UvrB k141_15806_6 1116375.VEJY3_10905 5.92e-280 769.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1XTGI@135623|Vibrionales 135623|Vibrionales T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains luxO GO:0000156,GO:0000160,GO:0003674,GO:0003700,GO:0006355,GO:0007154,GO:0007165,GO:0008150,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0023052,GO:0031323,GO:0031326,GO:0035556,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051716,GO:0060089,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 - ko:K10912 ko02020,ko02024,ko05111,map02020,map02024,map05111 M00513 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat k141_33632_1 1294265.JCM21738_5306 9.02e-17 77.4 COG0491@1|root,COG0491@2|Bacteria,1TQGU@1239|Firmicutes,4HBJ3@91061|Bacilli,1ZB0U@1386|Bacillus 91061|Bacilli S COG0491 Zn-dependent hydrolases, including glyoxylases yflN - - - - - - - - - - - Lactamase_B k141_33632_2 1294265.JCM21738_4762 1.59e-53 182.0 COG0449@1|root,COG0449@2|Bacteria,1TPGU@1239|Firmicutes,4H9R4@91061|Bacilli,1ZBI5@1386|Bacillus 91061|Bacilli M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source glmS GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 - R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 - - iSB619.SA_RS11245,iYO844.BSU01780 GATase_6,SIS k141_25316_2 675815.VOA_001524 1.79e-71 222.0 COG0384@1|root,COG0384@2|Bacteria,1R9X4@1224|Proteobacteria,1RZ0R@1236|Gammaproteobacteria,1XTKE@135623|Vibrionales 135623|Vibrionales S epimerase, PhzC PhzF homolog - - - - - - - - - - - - PhzC-PhzF k141_27596_2 1116375.VEJY3_11330 2.34e-50 160.0 2CJ8F@1|root,32SAV@2|Bacteria,1N0DT@1224|Proteobacteria,1S9BA@1236|Gammaproteobacteria,1XYEK@135623|Vibrionales 135623|Vibrionales S YfcL protein - - - - - - - - - - - - YfcL k141_27596_3 1116375.VEJY3_11335 1.91e-121 347.0 COG3101@1|root,COG3101@2|Bacteria,1MWTG@1224|Proteobacteria,1RNHD@1236|Gammaproteobacteria,1XTN3@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria yfcM - - ko:K09906 - - - - ko00000,ko01000,ko03012 - - - EpmC k141_27596_4 1116375.VEJY3_11340 1.63e-137 390.0 COG2860@1|root,COG2860@2|Bacteria,1R9H8@1224|Proteobacteria,1S00T@1236|Gammaproteobacteria,1XTZU@135623|Vibrionales 135623|Vibrionales S membrane yicG - - - - - - - - - - - UPF0126 k141_27596_5 223926.28807195 2.93e-258 708.0 COG0082@1|root,COG0082@2|Bacteria,1MU98@1224|Proteobacteria,1RMQS@1236|Gammaproteobacteria,1XSRC@135623|Vibrionales 135623|Vibrionales E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system aroC GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01714 RC00586 ko00000,ko00001,ko00002,ko01000 - - - Chorismate_synt k141_27596_6 1280001.BAOA01000009_gene4133 1.89e-226 623.0 COG2890@1|root,COG2890@2|Bacteria,1MX8Q@1224|Proteobacteria,1RPHQ@1236|Gammaproteobacteria,1XUD9@135623|Vibrionales 135623|Vibrionales J Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue prmB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006304,GO:0006305,GO:0006306,GO:0006464,GO:0006479,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009007,GO:0009008,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0032775,GO:0034641,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044728,GO:0046483,GO:0071704,GO:0090304,GO:0140096,GO:0140097,GO:1901360,GO:1901564 2.1.1.298 ko:K07320 - - R10806 RC00003,RC03279 ko00000,ko01000,ko03009 - - - MTS k141_27596_7 1116375.VEJY3_11355 3.28e-108 312.0 COG2840@1|root,COG2840@2|Bacteria,1MVS6@1224|Proteobacteria,1RPXD@1236|Gammaproteobacteria,1XUS2@135623|Vibrionales 135623|Vibrionales S Belongs to the UPF0115 family yfcN - - - - - - - - - - - Smr k141_20488_1 42565.FP66_05545 4.23e-46 157.0 COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,1RNCK@1236|Gammaproteobacteria,1XJ0K@135619|Oceanospirillales 135619|Oceanospirillales Q C4-dicarboxylate ABC transporter substrate-binding protein - - - - - - - - - - - - DctP k141_20488_2 42565.FP66_05550 4.01e-87 261.0 COG2186@1|root,COG2186@2|Bacteria,1MV83@1224|Proteobacteria,1RR9F@1236|Gammaproteobacteria,1XQ2G@135619|Oceanospirillales 135619|Oceanospirillales K FCD - - - - - - - - - - - - FCD,GntR k141_14579_1 797209.ZOD2009_11940 1.3e-67 224.0 COG1048@1|root,arCOG01697@2157|Archaea,2Y83G@28890|Euryarchaeota,23TWU@183963|Halobacteria 183963|Halobacteria C aconitate hydratase citB - 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_C k141_21753_1 1453501.JELR01000002_gene1382 5.24e-270 775.0 COG0591@1|root,COG0642@1|root,COG0784@1|root,COG0591@2|Bacteria,COG0784@2|Bacteria,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,1RP2U@1236|Gammaproteobacteria,465DY@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0591 Na proline symporter - - - - - - - - - - - - HATPase_c,HisKA,PAS_7,Response_reg,SSF k141_5110_1 1042377.AFPJ01000010_gene1454 8.68e-85 263.0 COG0577@1|root,COG0577@2|Bacteria,1QSVW@1224|Proteobacteria,1RPBM@1236|Gammaproteobacteria,465M6@72275|Alteromonadaceae 1236|Gammaproteobacteria V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD k141_13501_2 218284.CCDN010000002_gene2026 4.34e-13 67.4 COG1597@1|root,COG1597@2|Bacteria,1TQAU@1239|Firmicutes,4H9WD@91061|Bacilli,1ZBPD@1386|Bacillus 91061|Bacilli I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase dagK GO:0003674,GO:0003824,GO:0004143,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237 2.7.1.107 ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 - R02240 RC00002,RC00017 ko00000,ko00001,ko01000 - - - DAGK_cat k141_22990_1 218284.CCDN010000001_gene773 9.24e-116 335.0 COG1121@1|root,COG1121@2|Bacteria,1TQ68@1239|Firmicutes,4HAZI@91061|Bacilli,1ZBS5@1386|Bacillus 91061|Bacilli P 'COG1121 ABC-type Mn Zn transport systems, ATPase component' zurA - - ko:K02074,ko:K09817 ko02010,map02010 M00242,M00244 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 - - ABC_tran k141_9865_1 1279038.KB907343_gene2410 2.5e-36 140.0 COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,2TSU8@28211|Alphaproteobacteria,2JPV0@204441|Rhodospirillales 204441|Rhodospirillales S Polyphosphate kinase 2 (PPK2) - - - - - - - - - - - - PPK2 k141_8688_2 1219076.N646_0186 2.72e-122 354.0 COG0040@1|root,COG0040@2|Bacteria,1MUCY@1224|Proteobacteria,1RNAX@1236|Gammaproteobacteria,1XTJ4@135623|Vibrionales 135623|Vibrionales F Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity hisG GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 ko:K00765 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002,ko01000 - - - HisG,HisG_C k141_37124_1 595460.RRSWK_02852 3.34e-37 133.0 COG3153@1|root,COG3153@2|Bacteria,2IZPX@203682|Planctomycetes 203682|Planctomycetes S Acetyltransferase (GNAT) family - - - ko:K03824 - - - - ko00000,ko01000 - - - Acetyltransf_9 k141_37124_2 1114964.L485_10130 5.39e-34 120.0 2C3CF@1|root,32RRR@2|Bacteria,1MZUG@1224|Proteobacteria,2UC1Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF3175) - - - - - - - - - - - - DUF3175 k141_37124_3 1042377.AFPJ01000015_gene1616 1.62e-140 402.0 COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,1RMBB@1236|Gammaproteobacteria,46560@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 k141_37124_4 1127673.GLIP_0967 1.5e-53 188.0 COG1680@1|root,COG1680@2|Bacteria,1RIU7@1224|Proteobacteria 1224|Proteobacteria V COG1680 Beta-lactamase class C and other penicillin binding proteins - - - - - - - - - - - - Beta-lactamase k141_37124_5 706191.PANA_1927 6.05e-26 102.0 COG0346@1|root,COG0346@2|Bacteria,1RCX8@1224|Proteobacteria,1S551@1236|Gammaproteobacteria,3W0WV@53335|Pantoea 1236|Gammaproteobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - Glyoxalase k141_37124_6 323848.Nmul_A2158 2.08e-103 313.0 COG0430@1|root,COG0430@2|Bacteria,1MX7Q@1224|Proteobacteria,2VHYS@28216|Betaproteobacteria,373YE@32003|Nitrosomonadales 28216|Betaproteobacteria A Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP rtcA - 6.5.1.4 ko:K01974 - - - - ko00000,ko01000 - - - RTC,RTC_insert k141_5111_1 1485543.JMME01000015_gene210 9.32e-72 229.0 COG0112@1|root,COG0112@2|Bacteria,1TQVM@1239|Firmicutes,4H1W8@909932|Negativicutes 909932|Negativicutes E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism glyA - 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 - - - SHMT k141_2753_1 1294265.JCM21738_3698 2.23e-91 279.0 COG0852@1|root,COG0852@2|Bacteria,1UFNI@1239|Firmicutes,4HDV1@91061|Bacilli,1ZB7U@1386|Bacillus 91061|Bacilli C COG0852 NADH ubiquinone oxidoreductase 27 kD subunit nuoC - 1.6.5.3 ko:K00332 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_30kDa k141_26684_1 223926.28807723 6.23e-251 701.0 COG3307@1|root,COG3307@2|Bacteria,1N5VZ@1224|Proteobacteria,1RMC4@1236|Gammaproteobacteria,1XUTS@135623|Vibrionales 135623|Vibrionales M COG3307 Lipid A core - O-antigen ligase and related enzymes - - - ko:K13009 - - - - ko00000,ko01000,ko01005 - - - PglL_A,Wzy_C,Wzy_C_2 k141_28903_1 218284.CCDN010000001_gene142 7.22e-246 686.0 COG1217@1|root,COG1217@2|Bacteria,1TQ5Y@1239|Firmicutes,4HAQ6@91061|Bacilli,1ZB9R@1386|Bacillus 91061|Bacilli T GTP-binding protein TypA typA - - ko:K06207 - - - - ko00000 - - - EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2 k141_8689_1 218284.CCDN010000004_gene3039 1.99e-79 251.0 COG3428@1|root,COG3428@2|Bacteria,1TSRJ@1239|Firmicutes,4HB8P@91061|Bacilli,1ZBIF@1386|Bacillus 91061|Bacilli S Membrane ydbT - - ko:K08981 - - - - ko00000 - - - bPH_2 k141_31261_1 1232683.ADIMK_3734 1.14e-09 58.5 COG3007@1|root,COG3007@2|Bacteria,1MWCQ@1224|Proteobacteria,1RPPP@1236|Gammaproteobacteria,4657U@72275|Alteromonadaceae 1236|Gammaproteobacteria I Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP) fabV - 1.3.1.44,1.3.1.9 ko:K00209 ko00061,ko00650,ko01100,ko01120,ko01200,ko01212,map00061,map00650,map01100,map01120,map01200,map01212 M00083 R01171,R04429,R04724,R04955,R04958,R04961,R04966,R04969 RC00052,RC00076 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Eno-Rase_FAD_bd,Eno-Rase_NADH_b,Enoyl_reductase k141_452_1 1294265.JCM21738_2889 1.46e-89 265.0 COG3387@1|root,COG3387@2|Bacteria,1U9SF@1239|Firmicutes,4IJZD@91061|Bacilli,1ZETC@1386|Bacillus 91061|Bacilli G PFAM Glycoside hydrolase 15-related - - - - - - - - - - - - - k141_452_2 1294265.JCM21738_2888 2.6e-84 259.0 COG0438@1|root,COG0438@2|Bacteria,1V2NV@1239|Firmicutes,4HE1F@91061|Bacilli,1ZS6K@1386|Bacillus 91061|Bacilli M Glycosyl transferases group 1 yqgM - 2.4.1.250 ko:K15521 - - - - ko00000,ko01000 - - - Glyco_transf_4,Glycos_transf_1 k141_1489_1 666686.B1NLA3E_03725 3.16e-18 84.3 COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,4H9SB@91061|Bacilli,1ZBAN@1386|Bacillus 91061|Bacilli S COG1253 Hemolysins and related proteins containing CBS domains - - - - - - - - - - - - CBS,CorC_HlyC,DUF21 k141_1489_2 1294265.JCM21738_1957 2.8e-116 341.0 COG3852@1|root,COG3852@2|Bacteria,1TRH0@1239|Firmicutes,4HD4A@91061|Bacilli,1ZARI@1386|Bacillus 91061|Bacilli T COG0642 Signal transduction histidine kinase kinC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 ko:K02491,ko:K07698 ko02020,map02020 M00485 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS,PAS_3,PAS_9 k141_11048_1 1392490.JHZX01000001_gene418 5.47e-20 84.3 2B9ZZ@1|root,323DM@2|Bacteria,4NTEB@976|Bacteroidetes,1I2YU@117743|Flavobacteriia 976|Bacteroidetes S COG NOG15344 non supervised orthologous group - - - - - - - - - - - - - k141_9867_1 1294265.JCM21738_3155 1.54e-84 254.0 COG1404@1|root,COG1404@2|Bacteria,1V3SC@1239|Firmicutes,4HGZF@91061|Bacilli,1ZGVY@1386|Bacillus 91061|Bacilli O Domain of unknown function (DUF4397) - - - - - - - - - - - - DUF4397 k141_20490_1 1056820.KB900674_gene2662 1.87e-88 281.0 COG3507@1|root,COG3507@2|Bacteria,1R4H2@1224|Proteobacteria,1RSCC@1236|Gammaproteobacteria,2PQ2B@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria G C-terminal of Glycosyl hydrolases family 43 - - 3.2.1.99 ko:K06113 - - - - ko00000,ko01000 - GH43 - CBM_6,GH43_C,Glyco_hydro_43,RicinB_lectin_2 k141_13503_1 1423321.AS29_21835 3.76e-45 159.0 COG4552@1|root,COG4552@2|Bacteria,1TRPM@1239|Firmicutes,4HD22@91061|Bacilli,1ZB8R@1386|Bacillus 91061|Bacilli S Acetyltransferase - - - - - - - - - - - - Acetyltransf_9,SCP2_2 k141_34804_1 223926.28809562 5.51e-19 84.7 2DMIH@1|root,32RT1@2|Bacteria,1RDKU@1224|Proteobacteria,1S562@1236|Gammaproteobacteria,1XWDK@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_34804_2 1116375.VEJY3_17661 6.7e-30 106.0 2AWWE@1|root,31NTX@2|Bacteria,1QKI0@1224|Proteobacteria,1TIN5@1236|Gammaproteobacteria,1XZD2@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_34804_3 1116375.VEJY3_17656 7.03e-129 368.0 COG2197@1|root,COG2197@2|Bacteria,1Q7GF@1224|Proteobacteria,1RWWU@1236|Gammaproteobacteria,1XUUA@135623|Vibrionales 135623|Vibrionales K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain narP - - ko:K07685 ko02020,map02020 M00472 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg k141_34804_4 1116375.VEJY3_17651 0.0 995.0 COG3850@1|root,COG3850@2|Bacteria,1MWZT@1224|Proteobacteria,1RNPP@1236|Gammaproteobacteria,1XSRJ@135623|Vibrionales 135623|Vibrionales T COG3850 Signal transduction histidine kinase, nitrate nitrite-specific narQ - 2.7.13.3 ko:K07674 ko02020,map02020 M00472 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA_3,PilJ k141_34804_5 223926.28809565 1.21e-94 278.0 COG1143@1|root,COG1145@1|root,COG1143@2|Bacteria,COG1145@2|Bacteria,1N09Y@1224|Proteobacteria,1S4EB@1236|Gammaproteobacteria,1XWXY@135623|Vibrionales 135623|Vibrionales C COG1145 Ferredoxin napF - - ko:K02572 - - - - ko00000 - - - Fer4,Fer4_4,Fer4_7,Fer4_9 k141_34804_6 223926.28809566 2.22e-55 174.0 COG3062@1|root,COG3062@2|Bacteria,1NGMR@1224|Proteobacteria,1SGGG@1236|Gammaproteobacteria,1XXWG@135623|Vibrionales 135623|Vibrionales P protein involved in formation of periplasmic nitrate reductase napD - - ko:K02570 - - - - ko00000 - - - NapD k141_34804_7 1116375.VEJY3_17636 0.0 1659.0 COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,1RMWN@1236|Gammaproteobacteria,1XU9K@135623|Vibrionales 135623|Vibrionales C Catalytic subunit of the nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC. Essential function for nitrate assimilation and may have a role in anaerobic metabolism napA GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0008150,GO:0008152,GO:0008940,GO:0009325,GO:0016491,GO:0016651,GO:0016661,GO:0032991,GO:0048037,GO:0051536,GO:0051540,GO:0055114,GO:1902494 - ko:K02567 ko00910,ko01120,map00910,map01120 M00529,M00530 R00798,R01106 RC02812 ko00000,ko00001,ko00002,ko01000 - - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding k141_34804_8 223926.28809568 1.25e-100 292.0 COG3043@1|root,COG3043@2|Bacteria,1RH0X@1224|Proteobacteria,1T0CQ@1236|Gammaproteobacteria,1XWYR@135623|Vibrionales 135623|Vibrionales C Electron transfer subunit of the periplasmic nitrate reductase complex NapAB napB - - ko:K02568 ko00910,ko01120,map00910,map01120 M00529,M00530 R00798 RC02812 ko00000,ko00001,ko00002 - - - NapB k141_34804_9 1116375.VEJY3_17626 1.61e-141 399.0 COG3005@1|root,COG3005@2|Bacteria,1MWV2@1224|Proteobacteria,1RQ9A@1236|Gammaproteobacteria,1XSSS@135623|Vibrionales 135623|Vibrionales C COG3005 Nitrate TMAO reductases, membrane-bound tetraheme cytochrome c subunit napC - - ko:K02569 - - - - ko00000 - - - Cytochrom_NNT k141_34804_10 1041147.AUFB01000019_gene5569 4.05e-30 134.0 COG2199@1|root,COG3829@1|root,COG3706@2|Bacteria,COG3829@2|Bacteria,1R754@1224|Proteobacteria,2U48Q@28211|Alphaproteobacteria,4BCD9@82115|Rhizobiaceae 28211|Alphaproteobacteria T GGDEF domain - - - - - - - - - - - - 5TM-5TMR_LYT,GGDEF,PAS_4,PAS_7 k141_19345_1 223926.28809410 5.45e-212 590.0 COG4175@1|root,COG4175@2|Bacteria,1MU86@1224|Proteobacteria,1RY4K@1236|Gammaproteobacteria,1Y2HJ@135623|Vibrionales 135623|Vibrionales E COG4175 ABC-type proline glycine betaine transport system, ATPase component choV - 3.6.3.32 ko:K02000 ko02010,map02010 M00208 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.12 - - ABC_tran k141_19345_2 674977.VMC_00470 3.71e-151 429.0 COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,1RNW8@1236|Gammaproteobacteria,1XUZH@135623|Vibrionales 135623|Vibrionales O COG0330 Membrane protease subunits, stomatin prohibitin homologs - - - - - - - - - - - - Band_7 k141_19345_3 1116375.VEJY3_18621 2.15e-231 647.0 COG1030@1|root,COG1030@2|Bacteria,1MUJN@1224|Proteobacteria,1RN3U@1236|Gammaproteobacteria,1XV48@135623|Vibrionales 135623|Vibrionales O COG1030 Membrane-bound serine protease (ClpP class) - - - ko:K07403 - - - - ko00000 - - - NfeD k141_25317_2 1116375.VEJY3_06945 2.3e-127 362.0 2AMHM@1|root,31CD7@2|Bacteria,1QJG8@1224|Proteobacteria,1THFW@1236|Gammaproteobacteria,1XVH7@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_25344_1 1453501.JELR01000002_gene206 1.04e-102 305.0 COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,1RPSV@1236|Gammaproteobacteria,465UN@72275|Alteromonadaceae 1236|Gammaproteobacteria F Belongs to the ATCase OTCase family pyrB GO:0003674,GO:0003824,GO:0004070,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 - - iZ_1308.Z5856 OTCace,OTCace_N k141_14598_1 1279017.AQYJ01000024_gene1148 2.72e-106 321.0 COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RQTU@1236|Gammaproteobacteria,465ST@72275|Alteromonadaceae 1236|Gammaproteobacteria C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family merA - - - - - - - - - - - Pyr_redox_2,Pyr_redox_dim,SNARE_assoc k141_14598_2 323261.Noc_0589 4.06e-58 199.0 COG0398@1|root,COG1249@1|root,COG0398@2|Bacteria,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RQTU@1236|Gammaproteobacteria,1X2Q6@135613|Chromatiales 135613|Chromatiales C SNARE associated Golgi protein - - - - - - - - - - - - Pyr_redox_2,Pyr_redox_dim,SNARE_assoc k141_26712_1 1453501.JELR01000001_gene2321 2.24e-38 145.0 COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,1RMFJ@1236|Gammaproteobacteria,466DQ@72275|Alteromonadaceae 1236|Gammaproteobacteria H COG4206 Outer membrane cobalamin receptor protein btuB - - ko:K16092 - - - - ko00000,ko02000 1.B.14.3 - - Plug,TonB_dep_Rec k141_17009_1 218284.CCDN010000005_gene3187 7.96e-30 115.0 COG4758@1|root,COG4758@2|Bacteria,1TSDR@1239|Firmicutes,4HCRP@91061|Bacilli,1ZE5M@1386|Bacillus 91061|Bacilli S Cell wall-active antibiotics response 4TMS YvqF - - - ko:K11622 ko02020,map02020 - - - ko00000,ko00001 - - - DUF2154 k141_29992_1 1116375.VEJY3_22311 5.31e-93 280.0 COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,1RR9N@1236|Gammaproteobacteria,1XUEG@135623|Vibrionales 135623|Vibrionales S Predicted permease - - - ko:K07089 - - - - ko00000 - - - ArsP_1 k141_7459_2 1499689.CCNN01000009_gene2751 1.77e-21 92.4 COG3173@1|root,COG3173@2|Bacteria,1V3EC@1239|Firmicutes,25BZD@186801|Clostridia 186801|Clostridia S Protein of unknown function (DUF1679) - - - - - - - - - - - - APH k141_19371_1 218284.CCDN010000002_gene2596 6.66e-81 254.0 COG4191@1|root,COG4191@2|Bacteria,1UZ9W@1239|Firmicutes,4HDK2@91061|Bacilli,1ZD85@1386|Bacillus 91061|Bacilli T Histidine kinase kinB - 2.7.13.3 ko:K07697 ko02020,map02020 M00485 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - 5TM-5TMR_LYT,HATPase_c,HisKA k141_9900_1 1453501.JELR01000005_gene1791 6.05e-120 371.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,464CD@72275|Alteromonadaceae 1236|Gammaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family mtrD_1 - - ko:K18138,ko:K18307 ko01501,ko01503,ko02024,map01501,map01503,map02024 M00644,M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2,2.A.6.2.20,2.A.6.2.32 - - ACR_tran k141_33671_1 218284.CCDN010000001_gene285 2.05e-59 187.0 COG0640@1|root,COG0640@2|Bacteria,1V859@1239|Firmicutes,4HPKE@91061|Bacilli,1ZHZT@1386|Bacillus 91061|Bacilli K helix_turn_helix, Arsenical Resistance Operon Repressor kmtR - - ko:K21903 - - - - ko00000,ko03000 - - - HTH_5 k141_20515_1 1116375.VEJY3_08260 1.51e-296 810.0 COG0160@1|root,COG0160@2|Bacteria,1MWY6@1224|Proteobacteria,1RMP0@1236|Gammaproteobacteria,1XWB6@135623|Vibrionales 135623|Vibrionales E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family puuE - 2.6.1.19,2.6.1.22 ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 M00027 R00908,R01648,R04188 RC00006,RC00062,RC00160 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 k141_4034_1 42565.FP66_05545 3.17e-136 391.0 COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,1RNCK@1236|Gammaproteobacteria,1XJ0K@135619|Oceanospirillales 135619|Oceanospirillales Q C4-dicarboxylate ABC transporter substrate-binding protein - - - - - - - - - - - - DctP k141_32362_1 1243664.CAVL020000045_gene2073 2.71e-46 151.0 2F639@1|root,33YMK@2|Bacteria,1VXAY@1239|Firmicutes,4HXR4@91061|Bacilli,1ZHQ8@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3888) - - - - - - - - - - - - DUF3888 k141_11313_1 1123236.KB899387_gene1933 1.1e-67 213.0 COG1587@1|root,COG1587@2|Bacteria,1MWZD@1224|Proteobacteria,1RM9K@1236|Gammaproteobacteria,467TJ@72275|Alteromonadaceae 1236|Gammaproteobacteria H Uroporphyrinogen-III synthase hemD GO:0003674,GO:0003824,GO:0004852,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.75 ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R03165 RC01861 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_0187,iSBO_1134.SBO_3815 HEM4 k141_33829_2 1279017.AQYJ01000022_gene2608 6.61e-214 593.0 COG2304@1|root,COG2304@2|Bacteria,1QBPM@1224|Proteobacteria,1RQIU@1236|Gammaproteobacteria,466ZS@72275|Alteromonadaceae 1236|Gammaproteobacteria S Secreted protein, containing von Willebrand factor - - - - - - - - - - - - - k141_33829_3 1453501.JELR01000001_gene3248 1.43e-40 140.0 2C5F4@1|root,31I7F@2|Bacteria,1RHUH@1224|Proteobacteria,1S7M2@1236|Gammaproteobacteria,46BAF@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_35032_1 1089552.KI911559_gene3176 3.37e-28 114.0 COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,2TQWP@28211|Alphaproteobacteria,2JRCE@204441|Rhodospirillales 204441|Rhodospirillales E Gamma-glutamyltranspeptidase - - 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept k141_10152_1 323850.Shew_2744 1.08e-70 226.0 COG2819@1|root,COG2819@2|Bacteria,1RB1X@1224|Proteobacteria,1RY80@1236|Gammaproteobacteria,2QBJQ@267890|Shewanellaceae 1236|Gammaproteobacteria S Putative esterase - - - ko:K07017 - - - - ko00000 - - - Esterase k141_18457_1 1034943.BN1094_03788 1.71e-11 63.2 COG0346@1|root,COG0346@2|Bacteria,1RH79@1224|Proteobacteria,1S9UN@1236|Gammaproteobacteria,1JFBB@118969|Legionellales 118969|Legionellales E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - Glyoxalase k141_18457_2 1331660.L313_0259 9.31e-07 54.7 COG1670@1|root,COG1670@2|Bacteria,1MVG4@1224|Proteobacteria,1RQPX@1236|Gammaproteobacteria,3NKEY@468|Moraxellaceae 1236|Gammaproteobacteria J Acetyltransferase (GNAT) domain rimJ GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008999,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031365,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0051604,GO:0071704,GO:1901564 2.3.1.128 ko:K03790 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 k141_18457_3 1042377.AFPJ01000032_gene2780 1.93e-58 185.0 2FAHI@1|root,342RK@2|Bacteria,1NXJ2@1224|Proteobacteria,1SQ04@1236|Gammaproteobacteria 1236|Gammaproteobacteria S COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) - - - - - - - - - - - - - k141_21913_1 1122194.AUHU01000011_gene1720 3.7e-186 550.0 COG1629@1|root,COG4771@2|Bacteria,1N6JG@1224|Proteobacteria,1RP10@1236|Gammaproteobacteria,465FE@72275|Alteromonadaceae 1236|Gammaproteobacteria P Carboxypeptidase regulatory-like domain - - - - - - - - - - - - CarboxypepD_reg,Plug,TonB_dep_Rec k141_12606_1 1453501.JELR01000002_gene1518 6.6e-69 228.0 COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,1RPF7@1236|Gammaproteobacteria,46550@72275|Alteromonadaceae 1236|Gammaproteobacteria CO Thiol disulfide interchange protein dsbD - 1.8.1.8 ko:K04084 - - - - ko00000,ko01000,ko03110 5.A.1.1 - - DsbC,DsbD,Thioredoxin_7 k141_33830_1 314265.R2601_00025 1.79e-98 292.0 COG0329@1|root,COG0329@2|Bacteria,1MXI1@1224|Proteobacteria,2TTBJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) - - 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS k141_29030_1 42565.FP66_08970 2.71e-110 342.0 COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,1RN8K@1236|Gammaproteobacteria,1XHDK@135619|Oceanospirillales 135619|Oceanospirillales C 2-oxoglutarate dehydrogenase sucA - 1.2.4.2 ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R00621,R01933,R01940,R03316,R08549 RC00004,RC00027,RC00627,RC02743,RC02833,RC02883 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr k141_32492_1 218284.CCDN010000008_gene4130 3.62e-103 334.0 COG0366@1|root,COG1523@1|root,COG5492@1|root,COG0366@2|Bacteria,COG1523@2|Bacteria,COG5492@2|Bacteria,1TP3M@1239|Firmicutes,4HBP5@91061|Bacilli,1ZC85@1386|Bacillus 91061|Bacilli G Belongs to the glycosyl hydrolase 13 family pulA2 - 3.2.1.1,3.2.1.41 ko:K01176,ko:K01200 ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973 - R02108,R02111,R02112,R11262 - ko00000,ko00001,ko01000 - CBM48,GH13 - Alpha-amylase,Big_2,CBM_48,G5,Gram_pos_anchor,PUD,SLH,YSIRK_signal k141_15949_1 1231057.AMGD01000087_gene965 3.53e-49 167.0 COG2267@1|root,COG2267@2|Bacteria,1V1Y6@1239|Firmicutes,4HFW7@91061|Bacilli,26FU2@186818|Planococcaceae 91061|Bacilli I Thioesterase domain pcaD - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 k141_10153_1 218284.CCDN010000002_gene2288 3.28e-34 127.0 COG1472@1|root,COG1472@2|Bacteria,1TP63@1239|Firmicutes,4HBDB@91061|Bacilli,1ZCGR@1386|Bacillus 91061|Bacilli G Belongs to the glycosyl hydrolase 3 family nagZ - 3.2.1.52 ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 M00628 R00022,R05963,R07809,R07810,R10831 RC00049 ko00000,ko00001,ko00002,ko01000 - - - DUF4309,Glyco_hydro_3 k141_11315_1 42565.FP66_10325 1e-117 345.0 COG1062@1|root,COG1062@2|Bacteria,1MUK4@1224|Proteobacteria,1RNQ4@1236|Gammaproteobacteria,1XH2U@135619|Oceanospirillales 135619|Oceanospirillales C Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily adhC - 1.1.1.1,1.1.1.284 ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 - R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N k141_25601_1 218284.CCDN010000001_gene1120 1.65e-107 317.0 2E49C@1|root,32Z54@2|Bacteria,1VH6M@1239|Firmicutes,4HQD6@91061|Bacilli,1ZDJG@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_18458_1 218284.CCDN010000001_gene611 4.96e-172 496.0 COG2199@1|root,COG3706@2|Bacteria,1TQIK@1239|Firmicutes,4HEDD@91061|Bacilli,1ZB59@1386|Bacillus 91061|Bacilli T COG2199 FOG GGDEF domain - - - - - - - - - - - - GAF,GAF_2,GGDEF k141_35033_1 1348635.BBJY01000028_gene2070 5.87e-37 135.0 COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,1RNCW@1236|Gammaproteobacteria,1XSRR@135623|Vibrionales 135623|Vibrionales S HI0933-like protein yhiN - - ko:K07007 - - - - ko00000 - - - HI0933_like k141_35033_2 1517416.IDAT_03755 1.24e-69 214.0 COG1846@1|root,COG1846@2|Bacteria,1RFUJ@1224|Proteobacteria,1S8JQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator - - - - - - - - - - - - MarR,MarR_2 k141_10154_1 506534.Rhein_3432 1e-24 101.0 COG2819@1|root,COG2819@2|Bacteria,1RAB4@1224|Proteobacteria,1S2JK@1236|Gammaproteobacteria 1236|Gammaproteobacteria G hydrolase of the alpha beta superfamily Z012_06880 - - - - - - - - - - - Esterase k141_37301_2 1002809.SSIL_1423 1.3e-207 582.0 COG4653@1|root,COG4653@2|Bacteria,1U3SF@1239|Firmicutes,4HAF8@91061|Bacilli,26H92@186818|Planococcaceae 91061|Bacilli S Phage capsid family - - - - - - - - - - - - Phage_capsid k141_37301_4 1169144.KB910924_gene335 5.49e-19 79.7 2E9EY@1|root,333N9@2|Bacteria,1VET0@1239|Firmicutes,4HP4N@91061|Bacilli,1ZIBK@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - Phage_connect_1 k141_23238_1 218284.CCDN010000005_gene3290 8.49e-92 281.0 COG4469@1|root,COG4469@2|Bacteria,1TRGD@1239|Firmicutes,4HFP5@91061|Bacilli,1ZCFD@1386|Bacillus 91061|Bacilli S Competence protein coiA - - ko:K06198 - - - - ko00000 - - - CoiA k141_12608_1 1379270.AUXF01000003_gene3386 4.3e-68 221.0 COG2204@1|root,COG2204@2|Bacteria,1ZSRQ@142182|Gemmatimonadetes 142182|Gemmatimonadetes T Bacterial regulatory protein, Fis family - - - - - - - - - - - - HTH_8,Response_reg,Sigma54_activat k141_25602_2 1196031.ALEG01000041_gene2678 6.94e-29 103.0 29SWK@1|root,30E2V@2|Bacteria,1UC24@1239|Firmicutes,4INI7@91061|Bacilli,1ZNIB@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_19587_1 1294265.JCM21738_337 8.75e-181 505.0 COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,4HBDV@91061|Bacilli,1ZB7R@1386|Bacillus 91061|Bacilli J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome tsf GO:0001871,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005623,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0019538,GO:0030246,GO:0030247,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 - ko:K02357 - - - - ko00000,ko03012,ko03029 - - - EF_TS k141_19587_2 1294265.JCM21738_338 6.37e-87 260.0 COG0528@1|root,COG0528@2|Bacteria,1TPXN@1239|Firmicutes,4H9UB@91061|Bacilli,1ZBMW@1386|Bacillus 91061|Bacilli F Catalyzes the reversible phosphorylation of UMP to UDP pyrH - 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 - R00158 RC00002 ko00000,ko00001,ko01000 - - iSB619.SA_RS06240 AA_kinase k141_32493_1 1216007.AOPM01000026_gene3251 1.17e-92 285.0 COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,1RN2V@1236|Gammaproteobacteria,2Q1UC@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria P Sulfatase - - 3.1.6.1 ko:K01130 ko00140,ko00600,map00140,map00600 - R03980,R04856 RC00128,RC00231 ko00000,ko00001,ko01000 - - - Sulfatase,Sulfatase_C k141_29032_1 42565.FP66_06435 1.21e-106 308.0 COG0250@1|root,COG0250@2|Bacteria,1MU14@1224|Proteobacteria,1RMW0@1236|Gammaproteobacteria,1XHMM@135619|Oceanospirillales 135619|Oceanospirillales K Participates in transcription elongation, termination and antitermination nusG - - ko:K02601 - - - - ko00000,ko03009,ko03021 - - - KOW,NusG k141_11317_2 1408303.JNJJ01000002_gene3934 1.17e-30 109.0 2E3SP@1|root,32YQ7@2|Bacteria,1VFJP@1239|Firmicutes,4HNJI@91061|Bacilli,1ZIXT@1386|Bacillus 91061|Bacilli S Belongs to the SspI family sspI - - ko:K06426 - - - - ko00000 - - - SSPI k141_37302_1 1294265.JCM21738_127 3.13e-113 335.0 COG0457@1|root,COG0457@2|Bacteria,1TT97@1239|Firmicutes,4HAIA@91061|Bacilli,1ZAZM@1386|Bacillus 91061|Bacilli S COG0457 FOG TPR repeat ypiA - - - - - - - - - - - TPR_16,TPR_19,TPR_2,TPR_7,TPR_8 k141_12609_1 1453501.JELR01000002_gene343 2.02e-105 317.0 COG0810@1|root,COG0810@2|Bacteria,1R65W@1224|Proteobacteria,1S133@1236|Gammaproteobacteria,466F5@72275|Alteromonadaceae 1236|Gammaproteobacteria M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - - - - - - - - - - TonB_C k141_14722_1 1385513.N780_07980 2.96e-12 67.8 2DBJR@1|root,2Z9N7@2|Bacteria,1TRSN@1239|Firmicutes,4HCDI@91061|Bacilli,2Y9GB@289201|Pontibacillus 91061|Bacilli S Spore germination B3/ GerAC like, C-terminal - - - ko:K06297 - - - - ko00000 - - - Spore_GerAC k141_14722_2 1340434.AXVA01000014_gene477 1.41e-38 143.0 COG0697@1|root,COG0697@2|Bacteria,1TP7K@1239|Firmicutes,4HAH1@91061|Bacilli,1ZBEF@1386|Bacillus 91061|Bacilli EG Spore germination protein gerKA - - ko:K06295 - - - - ko00000 - - - GerA k141_17130_4 672.VV93_v1c45360 3.27e-109 314.0 COG4807@1|root,COG4807@2|Bacteria,1RD33@1224|Proteobacteria,1S3ZU@1236|Gammaproteobacteria,1XVIX@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria - - - - - - - - - - - - DUF1456 k141_7597_1 1279017.AQYJ01000022_gene2593 0.0 1335.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,464R3@72275|Alteromonadaceae 1236|Gammaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K18989 - M00720 - - ko00000,ko00002,ko02000 2.A.6.2.30 - - ACR_tran k141_7597_2 1279017.AQYJ01000022_gene2592 1.1e-155 451.0 COG0845@1|root,COG0845@2|Bacteria,1MVFN@1224|Proteobacteria,1RNN6@1236|Gammaproteobacteria,466K4@72275|Alteromonadaceae 1236|Gammaproteobacteria M Biotin-lipoyl like - - - ko:K18990 - M00720 - - ko00000,ko00002,ko02000 2.A.6.2.30,8.A.1 - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 k141_7597_3 1453501.JELR01000001_gene3261 1.45e-130 374.0 COG0664@1|root,COG0664@2|Bacteria,1RA0I@1224|Proteobacteria,1S23G@1236|Gammaproteobacteria,4671P@72275|Alteromonadaceae 1236|Gammaproteobacteria T Cyclic nucleotide-monophosphate binding domain - - - - - - - - - - - - cNMP_binding k141_24272_1 1116375.VEJY3_05360 3.59e-66 211.0 COG3135@1|root,COG3135@2|Bacteria,1MUS1@1224|Proteobacteria,1RMD5@1236|Gammaproteobacteria,1XUP6@135623|Vibrionales 135623|Vibrionales Q Benzoate membrane transport protein - - - ko:K05782 - - - - ko00000,ko02000 2.A.46.1 - - BenE k141_19609_1 1307436.PBF_18349 2.99e-152 437.0 COG0477@1|root,COG2814@2|Bacteria,1TQHD@1239|Firmicutes,4HBCZ@91061|Bacilli,1ZDDG@1386|Bacillus 91061|Bacilli EGP COG0477 Permeases of the major facilitator superfamily - - - - - - - - - - - - MFS_1,Sugar_tr k141_26947_1 218284.CCDN010000001_gene696 2.89e-116 339.0 COG0826@1|root,COG0826@2|Bacteria,1TQIZ@1239|Firmicutes,4HA2T@91061|Bacilli,1ZAXB@1386|Bacillus 91061|Bacilli O Peptidase U32 yrrN - - ko:K08303 ko05120,map05120 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_U32 k141_17153_3 1078085.HMPREF1210_03099 8.09e-90 298.0 COG1404@1|root,COG1404@2|Bacteria,1TPH1@1239|Firmicutes,4HBQH@91061|Bacilli,26GW2@186818|Planococcaceae 91061|Bacilli O Peptidase inhibitor I9 prtS - 3.4.21.110,3.4.21.96 ko:K01361,ko:K08652 - - - - ko00000,ko01000,ko01002,ko03110 - - - FIVAR,Gram_pos_anchor,Inhibitor_I9,PA,Peptidase_S8,SLH,YSIRK_signal,fn3_5 k141_37327_1 1453501.JELR01000002_gene1336 1.22e-296 830.0 COG0823@1|root,COG0823@2|Bacteria,1R3VN@1224|Proteobacteria,1RNKG@1236|Gammaproteobacteria,46408@72275|Alteromonadaceae 1236|Gammaproteobacteria U COG0823 Periplasmic component of the Tol biopolymer transport system - - - - - - - - - - - - PD40 k141_32520_1 1538295.JY96_10710 3.12e-33 130.0 2BX8K@1|root,2ZAX5@2|Bacteria,1R8CR@1224|Proteobacteria,2VKU9@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k141_8946_1 1111732.AZOD01000002_gene1813 2.32e-80 260.0 COG0699@1|root,COG0699@2|Bacteria,1PFM1@1224|Proteobacteria,1RWW3@1236|Gammaproteobacteria,1XBN8@135614|Xanthomonadales 135614|Xanthomonadales S Dynamin family - - - - - - - - - - - - Dynamin_N k141_21933_1 1116375.VEJY3_04130 3.62e-270 744.0 COG0397@1|root,COG0397@2|Bacteria,1MVK3@1224|Proteobacteria,1RNCS@1236|Gammaproteobacteria,1XSQA@135623|Vibrionales 135623|Vibrionales S Belongs to the UPF0061 (SELO) family - - - - - - - - - - - - UPF0061 k141_21933_2 1116375.VEJY3_04125 4.81e-181 539.0 COG4412@1|root,COG4935@1|root,COG4412@2|Bacteria,COG4935@2|Bacteria,1RKAD@1224|Proteobacteria,1S8JD@1236|Gammaproteobacteria,1XSHD@135623|Vibrionales 135623|Vibrionales Q Immune inhibitor A peptidase M6 - - - - - - - - - - - - Peptidase_M6 k141_36101_2 1294265.JCM21738_2498 1.24e-12 66.2 COG1131@1|root,COG1131@2|Bacteria,1TP4J@1239|Firmicutes,4HBGH@91061|Bacilli,1ZB4N@1386|Bacillus 91061|Bacilli V ABC transporter, ATP-binding protein - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_13801_2 218284.CCDN010000002_gene2267 1.92e-48 162.0 2DD3E@1|root,2ZGB6@2|Bacteria,1W2GF@1239|Firmicutes,4HZGP@91061|Bacilli,1ZIDY@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF4825) - - - - - - - - - - - - DUF4825 k141_18488_1 218284.CCDN010000001_gene1685 8.72e-105 330.0 COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,4HC3Y@91061|Bacilli,1ZCCY@1386|Bacillus 91061|Bacilli V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family yerP1 - - - - - - - - - - - ACR_tran k141_15977_1 561177.ANHYDRO_00907 7.62e-19 80.5 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,22HEI@1570339|Peptoniphilaceae 186801|Clostridia CQ BMC NPD7_940 - - ko:K04027 - - - - ko00000 - - - BMC k141_15977_2 665959.HMPREF1013_03588 1.92e-118 342.0 COG4869@1|root,COG4869@2|Bacteria,1V242@1239|Firmicutes,4HAG3@91061|Bacilli,1ZGIE@1386|Bacillus 91061|Bacilli Q Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate - - 2.3.1.8 ko:K15024 ko00430,ko00620,ko00640,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00720,map01100,map01120,map01200 M00579 R00230,R00921 RC00004,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000 - - - PTAC k141_33855_2 218284.CCDN010000003_gene2980 8.9e-187 521.0 COG1947@1|root,COG1947@2|Bacteria,1TPXV@1239|Firmicutes,4HAV8@91061|Bacilli,1ZAYT@1386|Bacillus 91061|Bacilli I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol ispE GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096,M00582 R05634 RC00002,RC01439 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.29 - iYO844.BSU00460 GHMP_kinases_C,GHMP_kinases_N k141_37328_1 1379270.AUXF01000003_gene3394 7.56e-60 198.0 COG4972@1|root,COG4972@2|Bacteria,1ZSYA@142182|Gemmatimonadetes 142182|Gemmatimonadetes NU Type IV pilus assembly protein PilM; - - - ko:K02662 - - - - ko00000,ko02035,ko02044 - - - PilM_2 k141_5396_1 1121935.AQXX01000098_gene1662 3.3e-10 71.2 COG3386@1|root,COG3391@1|root,COG4625@1|root,COG4733@1|root,COG3386@2|Bacteria,COG3391@2|Bacteria,COG4625@2|Bacteria,COG4733@2|Bacteria,1R2J4@1224|Proteobacteria,1T5QW@1236|Gammaproteobacteria,1XQGX@135619|Oceanospirillales 135619|Oceanospirillales G Calx-beta domain - - - - - - - - - - - - Calx-beta k141_17155_1 1453501.JELR01000002_gene732 8.98e-27 107.0 COG4941@1|root,COG4941@2|Bacteria,1MU3D@1224|Proteobacteria,1RN25@1236|Gammaproteobacteria,46673@72275|Alteromonadaceae 1236|Gammaproteobacteria K RNA polymerase sigma factor containing a TPR repeat domain - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2,TPR_2 k141_17155_2 1453501.JELR01000002_gene731 8.83e-35 121.0 COG3795@1|root,COG3795@2|Bacteria,1N32U@1224|Proteobacteria,1S82G@1236|Gammaproteobacteria,467IZ@72275|Alteromonadaceae 1236|Gammaproteobacteria S YCII-related domain - - - - - - - - - - - - YCII k141_13802_1 757424.Hsero_3282 1.67e-38 138.0 COG2267@1|root,COG2267@2|Bacteria,1QTAP@1224|Proteobacteria,2VMEV@28216|Betaproteobacteria,47249@75682|Oxalobacteraceae 28216|Betaproteobacteria I Serine aminopeptidase, S33 - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 k141_25639_1 313603.FB2170_00325 1.43e-56 195.0 COG3509@1|root,COG3975@1|root,COG3509@2|Bacteria,COG3975@2|Bacteria,4NFU9@976|Bacteroidetes,1HZST@117743|Flavobacteriia 976|Bacteroidetes Q depolymerase - - - - - - - - - - - - - k141_8947_2 211114.JOEF01000004_gene6363 0.000996 40.8 COG1476@1|root,COG1476@2|Bacteria,2GQIU@201174|Actinobacteria,4E829@85010|Pseudonocardiales 201174|Actinobacteria K Cro/C1-type HTH DNA-binding domain - - - ko:K07729 - - - - ko00000,ko03000 - - - HTH_3 k141_31370_1 720555.BATR1942_17575 3.15e-106 321.0 COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,4HBR4@91061|Bacilli,1ZB39@1386|Bacillus 91061|Bacilli JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes dbpA GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 3.6.4.13 ko:K05592 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,DbpA,Helicase_C k141_1650_2 998674.ATTE01000001_gene3099 3.22e-82 249.0 COG1611@1|root,COG1611@2|Bacteria,1RD59@1224|Proteobacteria,1S4C3@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Belongs to the LOG family yvdD - 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - Lysine_decarbox k141_1650_3 1042377.AFPJ01000042_gene1020 2.04e-203 570.0 COG2942@1|root,COG2942@2|Bacteria,1MX1J@1224|Proteobacteria,1RSCF@1236|Gammaproteobacteria,465YE@72275|Alteromonadaceae 1236|Gammaproteobacteria G N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) yihS GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006066,GO:0006082,GO:0006790,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016853,GO:0016860,GO:0016861,GO:0019637,GO:0034308,GO:0042180,GO:0042802,GO:0044237,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0050089,GO:0061593,GO:0061720,GO:0071704,GO:1901135,GO:1901136,GO:1901575,GO:1901615,GO:1902776,GO:1902777 5.3.1.31 ko:K18479 - - R10765 RC00376 ko00000,ko01000 - - - GlcNAc_2-epim k141_19612_1 1131730.BAVI_25509 1.4e-90 279.0 COG0477@1|root,COG2814@2|Bacteria,1TPRN@1239|Firmicutes,4H9VV@91061|Bacilli,1ZAXQ@1386|Bacillus 91061|Bacilli EGP the major facilitator superfamily - - - - - - - - - - - - MFS_1 k141_37329_1 1145276.T479_16200 5.75e-20 94.4 COG5283@1|root,COG5412@1|root,COG5283@2|Bacteria,COG5412@2|Bacteria,1UWZ1@1239|Firmicutes,4I2HH@91061|Bacilli,3IZ9E@400634|Lysinibacillus 91061|Bacilli D phage tail tape measure protein - - - - - - - - - - - - PhageMin_Tail k141_6536_2 1117647.M5M_11050 1.52e-140 404.0 COG3221@1|root,COG3221@2|Bacteria,1MWFF@1224|Proteobacteria,1RSFI@1236|Gammaproteobacteria,1J5DW@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P COG3221 ABC-type phosphate phosphonate transport system, periplasmic component phnD - - ko:K02044 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - Phosphonate-bd k141_6536_3 1117647.M5M_11055 3.83e-60 195.0 COG3638@1|root,COG3638@2|Bacteria,1RF8E@1224|Proteobacteria,1S3VW@1236|Gammaproteobacteria,1J6F7@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P COG3638 ABC-type phosphate phosphonate transport system, ATPase component phnC - 3.6.3.28 ko:K02041 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.9 - - ABC_tran k141_6536_4 1117647.M5M_11060 1.31e-155 457.0 COG3639@1|root,COG3639@2|Bacteria,1N3HU@1224|Proteobacteria,1RYH5@1236|Gammaproteobacteria,1J7WT@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P COG3639 ABC-type phosphate phosphonate transport system, permease component phnE - - ko:K02042 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - BPD_transp_1 k141_2874_1 690850.Desaf_3501 7.27e-31 129.0 COG3210@1|root,COG4412@1|root,COG3210@2|Bacteria,COG4412@2|Bacteria,1R3SG@1224|Proteobacteria,42SZZ@68525|delta/epsilon subdivisions,2WPD0@28221|Deltaproteobacteria,2MEAM@213115|Desulfovibrionales 28221|Deltaproteobacteria M Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - - - - - - - - - - PA,Peptidase_M36,REJ k141_33856_1 1178482.BJB45_18485 3.65e-145 426.0 COG0529@1|root,COG2895@1|root,COG0529@2|Bacteria,COG2895@2|Bacteria,1MUD9@1224|Proteobacteria,1RME4@1236|Gammaproteobacteria,1XH42@135619|Oceanospirillales 135619|Oceanospirillales P Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily cysN - 2.7.1.25,2.7.7.4 ko:K00955,ko:K00956 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176,M00596 R00509,R00529,R04928,R04929 RC00002,RC00078,RC02809,RC02889 ko00000,ko00001,ko00002,ko01000 - - - APS_kinase,GTP_EFTU,GTP_EFTU_D3 k141_5397_1 218284.CCDN010000005_gene3367 3.38e-57 197.0 COG5002@1|root,COG5002@2|Bacteria,1VUBP@1239|Firmicutes,4HUPW@91061|Bacilli,1ZS15@1386|Bacillus 91061|Bacilli T Histidine kinase kinE - 2.7.13.3 ko:K13533 ko02020,map02020 M00485 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9 k141_10184_2 1283284.AZUK01000001_gene2456 1.53e-92 273.0 COG0634@1|root,COG0634@2|Bacteria 2|Bacteria F Belongs to the purine pyrimidine phosphoribosyltransferase family hpt - 2.4.2.8 ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 - R00190,R01132,R01229,R02142,R08237,R08238,R08245 RC00063,RC00122 ko00000,ko00001,ko01000 - - - Pribosyltran k141_10184_3 1517681.HW45_14660 2.24e-90 269.0 COG0110@1|root,COG0110@2|Bacteria,1RA2T@1224|Proteobacteria,1S3ZZ@1236|Gammaproteobacteria,1XUHN@135623|Vibrionales 135623|Vibrionales S COG0110 Acetyltransferase (isoleucine patch superfamily) - - 2.3.1.79 ko:K00661 - - - - ko00000,ko01000 - - - Hexapep,Hexapep_2,Mac k141_10184_4 545697.HMPREF0216_00769 7.36e-73 223.0 COG0110@1|root,COG0110@2|Bacteria,1TQEX@1239|Firmicutes,249KF@186801|Clostridia,36FMC@31979|Clostridiaceae 186801|Clostridia S maltose O-acetyltransferase - - 2.3.1.18 ko:K00633 - - - - ko00000,ko01000 - - - Hexapep,Hexapep_2,Mac k141_21935_1 1294265.JCM21738_546 5.02e-166 472.0 COG1966@1|root,COG1966@2|Bacteria,1TQN8@1239|Firmicutes,4H9SU@91061|Bacilli,1ZC6K@1386|Bacillus 91061|Bacilli T Carbon starvation protein cstA - - - - - - - - - - - CstA,CstA_5TM k141_12618_1 1116375.VEJY3_12000 0.0 1128.0 COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,1RP0K@1236|Gammaproteobacteria,1XTXD@135623|Vibrionales 135623|Vibrionales L COG0587 DNA polymerase III, alpha subunit dnaE GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon k141_12618_2 223926.28807302 1.35e-132 379.0 COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,1RQ4B@1236|Gammaproteobacteria,1XSNB@135623|Vibrionales 135623|Vibrionales L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03470 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_HII k141_12618_3 223926.28807303 1.97e-256 705.0 COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,1RNS1@1236|Gammaproteobacteria,1XSUV@135623|Vibrionales 135623|Vibrionales M Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxB GO:0003674,GO:0003824,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008194,GO:0008289,GO:0008610,GO:0008654,GO:0008915,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 ko:K00748 ko00540,ko01100,map00540,map01100 M00060 R04606 RC00005,RC00059 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT19 - LpxB k141_35313_1 666686.B1NLA3E_00870 3.51e-112 337.0 COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,4H9SB@91061|Bacilli,1ZBAN@1386|Bacillus 91061|Bacilli S COG1253 Hemolysins and related proteins containing CBS domains yhdP - - - - - - - - - - - CBS,CorC_HlyC,DUF21 k141_19828_1 218284.CCDN010000002_gene2247 4.14e-94 278.0 COG1670@1|root,COG1670@2|Bacteria,1V14M@1239|Firmicutes,4HFZG@91061|Bacilli,1ZG0F@1386|Bacillus 91061|Bacilli J Acetyltransferase (GNAT) domain - - 2.3.1.128 ko:K03790 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 k141_24587_1 1453501.JELR01000002_gene495 1.34e-85 262.0 COG0457@1|root,COG0457@2|Bacteria,1PNM7@1224|Proteobacteria,1RXYT@1236|Gammaproteobacteria,46D2N@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0457 FOG TPR repeat - - - - - - - - - - - - Alkyl_sulf_dimr,TPR_19,TPR_8 k141_27193_1 218284.CCDN010000007_gene3908 2.87e-165 471.0 COG3314@1|root,COG3314@2|Bacteria,1TR35@1239|Firmicutes,4HAB6@91061|Bacilli,1ZARZ@1386|Bacillus 91061|Bacilli S protein conserved in bacteria - - - - - - - - - - - - Gate k141_18783_1 1294265.JCM21738_4544 1.1e-96 286.0 2B51H@1|root,31XUS@2|Bacteria,1V6KA@1239|Firmicutes,4HKBP@91061|Bacilli,1ZFY9@1386|Bacillus 91061|Bacilli S Sporulation protein YunB (Spo_YunB) yunB - - - - - - - - - - - Spore_YunB k141_1846_1 1453501.JELR01000002_gene1416 3.68e-147 419.0 COG0010@1|root,COG0010@2|Bacteria,1MVFH@1224|Proteobacteria,1RMH5@1236|Gammaproteobacteria,4689W@72275|Alteromonadaceae 1236|Gammaproteobacteria E Arginase family speB GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008783,GO:0009058,GO:0009308,GO:0009309,GO:0009445,GO:0009446,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0030145,GO:0034641,GO:0042401,GO:0043167,GO:0043169,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.1,3.5.3.11,3.5.3.17,3.5.3.7,3.5.3.8 ko:K01476,ko:K01479,ko:K01480,ko:K12255,ko:K18459 ko00220,ko00330,ko00340,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map00340,map01100,map01110,map01130,map01230,map05146 M00029,M00045,M00133,M00134 R00551,R01157,R01990,R02285 RC00024,RC00221,RC00329,RC00681 ko00000,ko00001,ko00002,ko01000 - - iB21_1397.B21_02730,iECB_1328.ECB_02767,iECD_1391.ECD_02767,iSbBS512_1146.SbBS512_E3370 Arginase k141_22182_1 439235.Dalk_0903 2.61e-05 45.8 COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,42QSI@68525|delta/epsilon subdivisions,2WMNJ@28221|Deltaproteobacteria,2MHNG@213118|Desulfobacterales 28221|Deltaproteobacteria J Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins pcm - 2.1.1.77 ko:K00573 - - - - ko00000,ko01000 - - - PCMT k141_22182_3 290397.Adeh_3339 6.12e-20 92.0 COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,42MJB@68525|delta/epsilon subdivisions,2WIXF@28221|Deltaproteobacteria,2YUHY@29|Myxococcales 28221|Deltaproteobacteria M penicillin-binding protein mrcA - 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 iAF987.Gmet_0354 PCB_OB,Transgly,Transpeptidase k141_29270_1 218284.CCDN010000002_gene2843 8.19e-141 402.0 COG1737@1|root,COG1737@2|Bacteria,1TR0N@1239|Firmicutes,4HB9E@91061|Bacilli,1ZCCD@1386|Bacillus 91061|Bacilli K RpiR family transcriptional regulator - - - - - - - - - - - - HTH_6,SIS k141_14107_1 1453501.JELR01000002_gene1011 1.24e-83 263.0 COG3540@1|root,COG3540@2|Bacteria,1MWAF@1224|Proteobacteria,1RNY4@1236|Gammaproteobacteria,464EY@72275|Alteromonadaceae 1236|Gammaproteobacteria P alkaline phosphatase phoD - 3.1.3.1 ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 M00126 R04620 RC00017 ko00000,ko00001,ko00002,ko01000 - - - PhoD,PhoD_N k141_12835_1 218284.CCDN010000002_gene2232 2.61e-79 248.0 COG3486@1|root,COG3486@2|Bacteria,1UZAQ@1239|Firmicutes,4HBWJ@91061|Bacilli,1ZB3E@1386|Bacillus 91061|Bacilli Q L-lysine 6-monooxygenase (NADPH-requiring) - - 1.14.13.59 ko:K03897 ko00310,ko01120,map00310,map01120 - R00448 RC00298 ko00000,ko00001,ko01000 - - - K_oxygenase k141_22183_1 1499680.CCFE01000030_gene3601 3.96e-60 197.0 COG0153@1|root,COG0153@2|Bacteria,1TPD0@1239|Firmicutes,4HARP@91061|Bacilli,1ZC9P@1386|Bacillus 91061|Bacilli G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) galK GO:0005975,GO:0005996,GO:0006012,GO:0008150,GO:0008152,GO:0019318,GO:0044238,GO:0044281,GO:0071704 2.7.1.6 ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00554,M00632 R01092 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko04147 - - - GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg k141_22183_2 326423.RBAM_012140 3.92e-07 50.8 COG1087@1|root,COG1087@2|Bacteria,1TQ7N@1239|Firmicutes,4H9U5@91061|Bacilli,1ZB5V@1386|Bacillus 91061|Bacilli M Belongs to the NAD(P)-dependent epimerase dehydratase family galE - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase,GDP_Man_Dehyd k141_24588_1 218284.CCDN010000006_gene3542 3.96e-128 373.0 COG1979@1|root,COG1979@2|Bacteria,1TPS3@1239|Firmicutes,4HT1J@91061|Bacilli,1ZEGP@1386|Bacillus 91061|Bacilli C Iron-containing alcohol dehydrogenase - - - ko:K19955 - - - - ko00000,ko01000 - - - Fe-ADH k141_7849_1 1294265.JCM21738_4173 3.18e-89 278.0 COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,4H9RZ@91061|Bacilli,1ZBEA@1386|Bacillus 91061|Bacilli NT chemotaxis protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - 4HB_MCP_1,HAMP,MCPsignal k141_9205_3 1565129.JSFF01000006_gene2554 5.76e-245 680.0 COG1680@1|root,COG1680@2|Bacteria,1P3SQ@1224|Proteobacteria,1SWQX@1236|Gammaproteobacteria,2QCYP@267890|Shewanellaceae 1236|Gammaproteobacteria V Beta-lactamase - - - - - - - - - - - - Beta-lactamase k141_20882_1 935836.JAEL01000017_gene792 1.64e-158 457.0 COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,4HA1G@91061|Bacilli,1ZASC@1386|Bacillus 91061|Bacilli G COG0366 Glycosidases yugT - 3.2.1.10,3.2.1.20 ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00028,R00801,R00802,R01718,R01791,R06087,R06088,R06199 RC00028,RC00049,RC00059,RC00077,RC00451 ko00000,ko00001,ko01000 - GH13,GH31 iSB619.SA_RS07580 Alpha-amylase,Malt_amylase_C k141_24614_2 935836.JAEL01000017_gene814 9.03e-92 271.0 COG4314@1|root,COG4314@2|Bacteria,1V8K0@1239|Firmicutes,4HTFN@91061|Bacilli,1ZF3Z@1386|Bacillus 91061|Bacilli C lipoprotein involved in nitrous oxide reduction - - - - - - - - - - - - - k141_6803_1 218284.CCDN010000001_gene1330 4.56e-268 758.0 COG0567@1|root,COG0567@2|Bacteria,1TRDW@1239|Firmicutes,4HAUI@91061|Bacilli,1ZAX3@1386|Bacillus 91061|Bacilli C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) odhA GO:0003674,GO:0003824,GO:0004591,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016624,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045333,GO:0055114,GO:0071704,GO:0072350,GO:1902494,GO:1990204,GO:1990234 1.2.4.2 ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R00621,R01933,R01940,R03316,R08549 RC00004,RC00027,RC00627,RC02743,RC02833,RC02883 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr k141_9233_1 1294265.JCM21738_2804 9.33e-137 388.0 COG1309@1|root,COG1309@2|Bacteria,1TRSH@1239|Firmicutes,4H9RC@91061|Bacilli,1ZAU5@1386|Bacillus 91061|Bacilli K Transcriptional regulator fadR GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - ko:K13770 - - - - ko00000,ko03000 - - - TetR_C_4,TetR_N k141_23549_1 218284.CCDN010000001_gene574 1.92e-73 231.0 COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,4HADX@91061|Bacilli,1ZDA6@1386|Bacillus 91061|Bacilli E Belongs to the aspartokinase family lysC GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,ACT,ACT_7 k141_5687_1 1307436.PBF_00510 7.53e-120 357.0 COG1178@1|root,COG1178@2|Bacteria,1TPMX@1239|Firmicutes,4HBPX@91061|Bacilli,1ZQES@1386|Bacillus 91061|Bacilli P Binding-protein-dependent transport system inner membrane component - - - ko:K02011 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - BPD_transp_1 k141_27237_1 935836.JAEL01000062_gene2110 1.86e-140 403.0 COG2103@1|root,COG2103@2|Bacteria,1TPSF@1239|Firmicutes,4HBWP@91061|Bacilli,1ZCFF@1386|Bacillus 91061|Bacilli G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate murQ - 4.2.1.126 ko:K07106 ko00520,ko01100,map00520,map01100 - R08555 RC00397,RC00746 ko00000,ko00001,ko01000 - - - SIS,SIS_2 k141_27237_2 218284.CCDN010000002_gene2838 1.23e-43 154.0 COG0277@1|root,COG0277@2|Bacteria,1TPBC@1239|Firmicutes,4H9UU@91061|Bacilli,1ZCQN@1386|Bacillus 91061|Bacilli C Glycolate oxidase subunit glcD - 1.1.3.15 ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001,ko01000 - - iYO844.BSU28680 FAD-oxidase_C,FAD_binding_4 k141_16215_1 1196031.ALEG01000040_gene2906 2.14e-36 127.0 COG4467@1|root,COG4467@2|Bacteria,1VA1F@1239|Firmicutes,4HKND@91061|Bacilli,1ZGZH@1386|Bacillus 91061|Bacilli L Involved in initiation control of chromosome replication yabA GO:0003674,GO:0005488,GO:0005515,GO:0042802 - - - - - - - - - - YabB k141_22221_1 223926.28807516 0.0 906.0 COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,1RNPT@1236|Gammaproteobacteria,1XT8J@135623|Vibrionales 135623|Vibrionales C The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) aceF - 2.3.1.12 ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding k141_22221_2 223926.28807515 2.53e-183 519.0 COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RMFF@1236|Gammaproteobacteria,1XT11@135623|Vibrionales 135623|Vibrionales C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes lpdA GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0045250,GO:0045254,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyr_redox_2,Pyr_redox_dim k141_3085_1 42565.FP66_05870 2.59e-130 377.0 COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,1RNID@1236|Gammaproteobacteria,1XI3Q@135619|Oceanospirillales 135619|Oceanospirillales M Catalyzes the transfer of a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge - - 2.1.1.79 ko:K00574 - - - - ko00000,ko01000 - - - CMAS k141_25888_1 997296.PB1_15039 4.24e-11 65.5 COG0840@1|root,COG0840@2|Bacteria,1TZ8Z@1239|Firmicutes,4HBMM@91061|Bacilli,1ZDNK@1386|Bacillus 91061|Bacilli NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). mcp4 - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal k141_25888_2 224308.BSU25040 1.26e-21 95.9 COG5521@1|root,COG5521@2|Bacteria,1V2MC@1239|Firmicutes,4HGIF@91061|Bacilli,1ZBMN@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF1189) yqgB - - - - - - - - - - - DUF1189 k141_35341_2 218284.CCDN010000002_gene2227 1.97e-65 208.0 COG0524@1|root,COG1522@1|root,COG0524@2|Bacteria,COG1522@2|Bacteria,1TQR4@1239|Firmicutes,4H9VM@91061|Bacilli,1ZBUP@1386|Bacillus 91061|Bacilli GK pfkB family carbohydrate kinase - - 2.7.1.83 ko:K16328 ko00240,map00240 - R03315 RC00002,RC00017 ko00000,ko00001,ko01000 - - - HTH_24,PfkB k141_6805_1 1121938.AUDY01000011_gene594 9.25e-29 112.0 COG3919@1|root,COG3919@2|Bacteria,1TQPN@1239|Firmicutes,4HAB0@91061|Bacilli,3NEMS@45667|Halobacillus 91061|Bacilli S D-ala D-ala ligase C-terminus yxbA - 6.3.1.12 ko:K17810 - - - - ko00000,ko01000 - - - - k141_27238_2 1273538.G159_03860 6.68e-56 181.0 COG1708@1|root,COG1708@2|Bacteria,1UD4J@1239|Firmicutes,4HDMK@91061|Bacilli,26DGY@186818|Planococcaceae 91061|Bacilli S nucleotidyltransferase activity - - - - - - - - - - - - NTP_transf_2 k141_12850_1 1042377.AFPJ01000034_gene2367 7.77e-184 525.0 COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,1RP25@1236|Gammaproteobacteria,465HJ@72275|Alteromonadaceae 1236|Gammaproteobacteria M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) murD GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008764,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - iAPECO1_1312.APECO1_1898,iECNA114_1301.ECNA114_0081,iECOK1_1307.ECOK1_0089,iECP_1309.ECP_0090,iECS88_1305.ECS88_0091,iECSF_1327.ECSF_0098,iLF82_1304.LF82_1418,iNRG857_1313.NRG857_00450,iUMN146_1321.UM146_23225,iUTI89_1310.UTI89_C0097 Mur_ligase_C,Mur_ligase_M k141_12850_3 1279017.AQYJ01000024_gene1087 1.09e-103 310.0 COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,1RMQ3@1236|Gammaproteobacteria,464K0@72275|Alteromonadaceae 1236|Gammaproteobacteria M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) murG GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008194,GO:0008375,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0050511,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.4.1.227 ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 - R05032,R05662 RC00005,RC00049 ko00000,ko00001,ko01000,ko01011 - GT28 iSFV_1184.SFV_0083,iSF_1195.SF0087,iSFxv_1172.SFxv_0091,iS_1188.S0089 Glyco_tran_28_C,Glyco_transf_28 k141_4306_1 864051.BurJ1DRAFT_3842 4.32e-81 261.0 COG1505@1|root,COG1505@2|Bacteria,1NZ7N@1224|Proteobacteria,2VHTT@28216|Betaproteobacteria,1KKFT@119065|unclassified Burkholderiales 28216|Betaproteobacteria E Prolyl oligopeptidase f1pep1 - 3.4.21.26 ko:K01322 ko04614,map04614 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S9,Peptidase_S9_N k141_879_1 1116375.VEJY3_04700 7.91e-116 352.0 COG2838@1|root,COG2838@2|Bacteria,1MV6Q@1224|Proteobacteria,1RPG4@1236|Gammaproteobacteria,1XUW0@135623|Vibrionales 135623|Vibrionales C Isocitrate dehydrogenase icd - 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 - - - IDH k141_879_2 674977.VMC_31300 2.21e-127 366.0 COG1187@1|root,COG1187@2|Bacteria,1R9VV@1224|Proteobacteria,1S1ZX@1236|Gammaproteobacteria,1XUNX@135623|Vibrionales 135623|Vibrionales J Belongs to the pseudouridine synthase RsuA family rluE GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.20 ko:K06181 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2 k141_879_3 1280001.BAOA01000060_gene2351 2e-116 338.0 COG3110@1|root,COG3110@2|Bacteria,1RK33@1224|Proteobacteria,1RZRX@1236|Gammaproteobacteria,1XXDK@135623|Vibrionales 135623|Vibrionales S Uncharacterized protein conserved in bacteria (DUF2057) - - - ko:K09909 - - - - ko00000 - - - DUF2057 k141_879_4 1280001.BAOA01000060_gene2352 2.29e-192 540.0 COG3203@1|root,COG3203@2|Bacteria,1NC33@1224|Proteobacteria,1T1EX@1236|Gammaproteobacteria,1XWCP@135623|Vibrionales 135623|Vibrionales M Gram-negative porin - - - ko:K10940 ko05111,map05111 - - - ko00000,ko00001,ko02000 1.B.1.8.1 - - Porin_4 k141_879_5 1116375.VEJY3_04680 0.0 1309.0 COG1199@1|root,COG1199@2|Bacteria,1MVCU@1224|Proteobacteria,1RMNX@1236|Gammaproteobacteria,1XSN4@135623|Vibrionales 135623|Vibrionales KL COG1199 Rad3-related DNA helicases dinG - 3.6.4.12 ko:K03722 - - - - ko00000,ko01000,ko03400 - - - DEAD_2,Helicase_C_2,ResIII k141_879_6 1116375.VEJY3_04675 4.98e-177 494.0 COG0730@1|root,COG0730@2|Bacteria,1MXNM@1224|Proteobacteria,1RRH4@1236|Gammaproteobacteria,1XU3C@135623|Vibrionales 135623|Vibrionales S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE k141_879_7 1116375.VEJY3_04670 1.21e-108 315.0 COG3923@1|root,COG3923@2|Bacteria,1RIA6@1224|Proteobacteria,1SB72@1236|Gammaproteobacteria,1Y2K8@135623|Vibrionales 135623|Vibrionales L Primosomal replication protein N'' - - - ko:K04067 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - PriC k141_879_8 223926.28805991 2.36e-22 87.0 2EHYU@1|root,33BQB@2|Bacteria,1NGAT@1224|Proteobacteria,1SGE4@1236|Gammaproteobacteria,1XZI3@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF2496) C0585 - - - - - - - - - - - DUF2496 k141_879_9 29495.EA26_05995 1.87e-287 810.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XUGQ@135623|Vibrionales 135623|Vibrionales NT methyl-accepting chemotaxis protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal,dCache_1 k141_879_10 223926.28805990 9.53e-199 550.0 COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,1RN4H@1236|Gammaproteobacteria,1XVBK@135623|Vibrionales 135623|Vibrionales L COG0708 Exonuclease III xthA - 3.1.11.2 ko:K01142 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Exo_endo_phos k141_879_11 1116375.VEJY3_04635 2.68e-152 429.0 COG4160@1|root,COG4160@2|Bacteria,1MWI6@1224|Proteobacteria,1RPT1@1236|Gammaproteobacteria,1XT23@135623|Vibrionales 135623|Vibrionales P COG4160 ABC-type arginine histidine transport system, permease component aotM - - ko:K10023 ko02010,map02010 M00235 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.11 - - BPD_transp_1 k141_879_12 1116375.VEJY3_04630 1.86e-160 451.0 COG4215@1|root,COG4215@2|Bacteria,1MY2N@1224|Proteobacteria,1RNYD@1236|Gammaproteobacteria,1XT6H@135623|Vibrionales 135623|Vibrionales P COG4215 ABC-type arginine transport system, permease component aotQ - - ko:K10024 ko02010,map02010 M00235 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.11 - - BPD_transp_1 k141_879_13 1219076.N646_0063 8.93e-173 483.0 COG0834@1|root,COG0834@2|Bacteria,1NT2J@1224|Proteobacteria,1S077@1236|Gammaproteobacteria,1XT44@135623|Vibrionales 135623|Vibrionales ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain aotJ - - ko:K10022 ko02010,map02010 M00235 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.11 - - SBP_bac_3 k141_879_14 1116375.VEJY3_04620 7.13e-179 498.0 COG4598@1|root,COG4598@2|Bacteria,1QTS2@1224|Proteobacteria,1RQYN@1236|Gammaproteobacteria,1XU3M@135623|Vibrionales 135623|Vibrionales E COG4598 ABC-type histidine transport system, ATPase component aotP - - ko:K10025 ko02010,map02010 M00235 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3.11 - - ABC_tran k141_24615_2 1453501.JELR01000001_gene1967 3.67e-127 363.0 COG3762@1|root,COG3762@2|Bacteria,1R61N@1224|Proteobacteria,1S2RR@1236|Gammaproteobacteria,466UH@72275|Alteromonadaceae 1236|Gammaproteobacteria S Membrane - - - ko:K08988 - - - - ko00000 - - - TPM_phosphatase k141_24615_3 1453501.JELR01000001_gene1966 2.65e-10 62.8 28RR1@1|root,2ZE3K@2|Bacteria,1P7PJ@1224|Proteobacteria,1SUUS@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain present in PSD-95, Dlg, and ZO-1/2. - - - - - - - - - - - - PDZ_2 k141_16216_1 378806.STAUR_7040 1.73e-33 125.0 COG0363@1|root,COG0363@2|Bacteria,1R5K6@1224|Proteobacteria,42UV6@68525|delta/epsilon subdivisions,2WP1R@28221|Deltaproteobacteria,2YVX1@29|Myxococcales 28221|Deltaproteobacteria G Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase pgl - 3.1.1.31 ko:K01057 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R02035 RC00537 ko00000,ko00001,ko00002,ko01000 - - - Glucosamine_iso k141_35342_1 1294265.JCM21738_141 6.69e-13 66.2 COG2120@1|root,COG2120@2|Bacteria,1TV10@1239|Firmicutes,4HFJQ@91061|Bacilli,1ZAZI@1386|Bacillus 91061|Bacilli S proteins, LmbE homologs ypjG - - ko:K01463 - - - - ko00000,ko01000 - - - PIG-L k141_6806_1 1347369.CCAD010000083_gene2828 2.64e-99 317.0 COG0457@1|root,COG0457@2|Bacteria,1TSH7@1239|Firmicutes,4HACN@91061|Bacilli,1ZBDH@1386|Bacillus 91061|Bacilli M Tetratricopeptide repeat - - - - - - - - - - - - - k141_3086_1 1453501.JELR01000005_gene1587 6.17e-132 387.0 COG0446@1|root,COG0446@2|Bacteria,1Q0P8@1224|Proteobacteria,1T1NQ@1236|Gammaproteobacteria,464PV@72275|Alteromonadaceae 1236|Gammaproteobacteria S Tryptophan halogenase - - 1.14.19.9 ko:K14266 ko00404,ko01130,map00404,map01130 M00789,M00790 R09570 RC00949 ko00000,ko00001,ko00002,ko01000 - - - Trp_halogenase k141_14978_1 218284.CCDN010000001_gene1870 1.71e-111 342.0 COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,4H9WA@91061|Bacilli,1ZANX@1386|Bacillus 91061|Bacilli D Belongs to the FtsK SpoIIIE SftA family ftsK GO:0000003,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma k141_34083_2 218284.CCDN010000007_gene3839 4.15e-146 413.0 COG0664@1|root,COG0664@2|Bacteria,1TT3C@1239|Firmicutes,4HFAQ@91061|Bacilli,1ZBP9@1386|Bacillus 91061|Bacilli T COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases nsr - - - - - - - - - - - HTH_Crp_2,cNMP_binding k141_34083_3 218284.CCDN010000007_gene3838 4.1e-145 418.0 COG0477@1|root,COG2814@2|Bacteria,1TR1D@1239|Firmicutes,4HA4Z@91061|Bacilli,1ZB9Z@1386|Bacillus 91061|Bacilli EGP COG0477 Permeases of the major facilitator superfamily - - - ko:K05820 - - - - ko00000,ko02000 2.A.1.27 - - MFS_1_like k141_19860_1 1298865.H978DRAFT_1333 1.32e-50 165.0 COG0563@1|root,COG0563@2|Bacteria,1REQW@1224|Proteobacteria,1S67T@1236|Gammaproteobacteria,466VT@72275|Alteromonadaceae 1236|Gammaproteobacteria F COG0563 Adenylate kinase and related kinases - - - - - - - - - - - - AAA_18 k141_19860_2 1453501.JELR01000005_gene1602 5.93e-63 194.0 COG0346@1|root,COG0346@2|Bacteria,1RH8Z@1224|Proteobacteria,1SAVZ@1236|Gammaproteobacteria,467S8@72275|Alteromonadaceae 1236|Gammaproteobacteria E Glyoxalase-like domain - - - - - - - - - - - - Glyoxalase k141_19860_3 1123059.KB823011_gene1698 9e-66 213.0 COG0657@1|root,COG0657@2|Bacteria,1R4AU@1224|Proteobacteria,2UBDM@28211|Alphaproteobacteria 28211|Alphaproteobacteria I Carboxylesterase family - - - - - - - - - - - - Abhydrolase_3 k141_35343_1 402777.KB235903_gene430 1.68e-19 82.0 2AFZF@1|root,3163A@2|Bacteria,1GG27@1117|Cyanobacteria 1117|Cyanobacteria - - - - - - - - - - - - - - - k141_16217_1 1453501.JELR01000001_gene2050 2.21e-17 81.3 COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,1RN03@1236|Gammaproteobacteria,4643E@72275|Alteromonadaceae 1236|Gammaproteobacteria L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrA GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0018130,GO:0019438,GO:0032774,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042493,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097659,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 5.99.1.3 ko:K02469 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseA_C,DNA_topoisoIV k141_10404_2 1279017.AQYJ01000028_gene2267 2.24e-168 477.0 COG0837@1|root,COG0837@2|Bacteria,1MVFI@1224|Proteobacteria,1RNUY@1236|Gammaproteobacteria,464W6@72275|Alteromonadaceae 1236|Gammaproteobacteria F Belongs to the bacterial glucokinase family glk - 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Glucokinase k141_10404_3 1042377.AFPJ01000004_gene340 2.02e-170 482.0 COG3833@1|root,COG3833@2|Bacteria,1R28D@1224|Proteobacteria,1T5IQ@1236|Gammaproteobacteria,46DBX@72275|Alteromonadaceae 1236|Gammaproteobacteria G Binding-protein-dependent transport system inner membrane component - - - ko:K15772 ko02010,map02010 M00491 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.16,3.A.1.1.2 - - BPD_transp_1 k141_881_1 1294265.JCM21738_3426 1.21e-45 158.0 COG0508@1|root,COG0508@2|Bacteria,1TQSH@1239|Firmicutes,4HBSU@91061|Bacilli,1ZC6F@1386|Bacillus 91061|Bacilli C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex bkdB - 2.3.1.12,2.3.1.168 ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 M00036,M00307 R00209,R02569,R02662,R03174,R04097,R10998 RC00004,RC02727,RC02742,RC02857,RC02870 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding k141_25889_1 218284.CCDN010000001_gene1495 5.18e-191 538.0 COG2233@1|root,COG2233@2|Bacteria,1TQ0A@1239|Firmicutes,4HA6X@91061|Bacilli,1ZD5W@1386|Bacillus 91061|Bacilli F Xanthine uracil ywdJ GO:0003674,GO:0005215,GO:0005345,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006863,GO:0008150,GO:0015205,GO:0015851,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0042906,GO:0042907,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072530,GO:1904823 - - - - - - - - - - Xan_ur_permease k141_9237_1 1279017.AQYJ01000029_gene3582 8.66e-186 552.0 COG1014@1|root,COG4231@1|root,COG1014@2|Bacteria,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,1RSEQ@1236|Gammaproteobacteria,465RF@72275|Alteromonadaceae 1236|Gammaproteobacteria C Pyruvate ferredoxin/flavodoxin oxidoreductase - - 1.2.7.8 ko:K04090 - - - - br01601,ko00000,ko01000 - - - POR,TPP_enzyme_C k141_4307_1 218284.CCDN010000005_gene3167 1.79e-65 228.0 COG4717@1|root,COG4717@2|Bacteria,1TQP3@1239|Firmicutes,4HBCA@91061|Bacilli,1ZDHB@1386|Bacillus 91061|Bacilli L AAA domain yhaN - - - - - - - - - - - AAA_27 k141_12852_1 1294265.JCM21738_5148 4.77e-76 229.0 2BG2F@1|root,329YP@2|Bacteria,1UCC8@1239|Firmicutes,4INUP@91061|Bacilli,1ZNZ0@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_18829_4 1453501.JELR01000002_gene674 6.69e-244 680.0 COG0811@1|root,COG0811@2|Bacteria,1MX5J@1224|Proteobacteria,1RMSA@1236|Gammaproteobacteria,4641Y@72275|Alteromonadaceae 1236|Gammaproteobacteria U MotA TolQ ExbB proton channel - - - ko:K03561 - - - - ko00000,ko02000 1.A.30.2.1 - - MotA_ExbB k141_18829_5 1042377.AFPJ01000024_gene798 3.61e-152 432.0 COG1196@1|root,COG1196@2|Bacteria,1NGHR@1224|Proteobacteria,1RQW7@1236|Gammaproteobacteria,464Q4@72275|Alteromonadaceae 1236|Gammaproteobacteria D Protein of unknown function (DUF3450) - - - - - - - - - - - - DUF3450 k141_23553_1 218284.CCDN010000001_gene1571 4.54e-171 492.0 COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HACS@91061|Bacilli,1ZATG@1386|Bacillus 91061|Bacilli IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - 6.2.1.3,6.2.1.34 ko:K01897,ko:K12508 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding,AMP-binding_C k141_29294_1 1116375.VEJY3_17736 1.63e-197 550.0 COG2358@1|root,COG2358@2|Bacteria,1MXW1@1224|Proteobacteria,1RYBC@1236|Gammaproteobacteria,1XTNX@135623|Vibrionales 135623|Vibrionales S ABC transporter, phosphonate, periplasmic substrate-binding protein - - - ko:K07080 - - - - ko00000 - - - NMT1_3 k141_29294_2 1116375.VEJY3_17741 8.82e-257 717.0 COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,1RMH7@1236|Gammaproteobacteria,1XV3R@135623|Vibrionales 135623|Vibrionales S Tripartite ATP-independent periplasmic transporter, DctM component - - - - - - - - - - - - DctM k141_31466_1 1112209.AHVZ01000041_gene796 3.98e-38 139.0 COG1278@1|root,COG3326@1|root,COG1278@2|Bacteria,COG3326@2|Bacteria,1N6YM@1224|Proteobacteria,1SCMX@1236|Gammaproteobacteria,3NJVM@468|Moraxellaceae 1236|Gammaproteobacteria K Protein of unknown function (DUF1294) - - - - - - - - - - - - CSD,DUF1294 k141_31466_2 1042377.AFPJ01000009_gene226 0.0 1104.0 COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,1RR1B@1236|Gammaproteobacteria,46421@72275|Alteromonadaceae 1236|Gammaproteobacteria L ATP-dependent helicase HrpB hrpB - 3.6.4.13 ko:K03579 - - - - ko00000,ko01000 - - - DEAD,HA2,Helicase_C,HrpB_C k141_17370_1 218284.CCDN010000001_gene140 1.3e-53 172.0 2E7TT@1|root,3328W@2|Bacteria,1VEEV@1239|Firmicutes,4HP4M@91061|Bacilli,1ZJC7@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_15005_1 1294265.JCM21738_4605 3.47e-127 378.0 COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HACY@91061|Bacilli,1ZB4C@1386|Bacillus 91061|Bacilli O Belongs to the ClpA ClpB family clpC GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 - ko:K03696 ko01100,map01100 - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N,UVR k141_9258_1 1116375.VEJY3_19651 0.0 1488.0 COG0243@1|root,COG0243@2|Bacteria,1MU6B@1224|Proteobacteria,1RNXW@1236|Gammaproteobacteria,1XVEA@135623|Vibrionales 135623|Vibrionales C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - - - - - - - - - - Molybdopterin,Molydop_binding k141_31606_2 1348635.BBJY01000005_gene3343 4.62e-119 347.0 COG1414@1|root,COG1414@2|Bacteria,1RG7W@1224|Proteobacteria,1S0AM@1236|Gammaproteobacteria,1XVYC@135623|Vibrionales 135623|Vibrionales K Transcriptional regulator - - - - - - - - - - - - HTH_IclR,IclR k141_31606_3 1188252.AJYK01000009_gene2750 9.02e-249 690.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,1RNAM@1236|Gammaproteobacteria,1XTIW@135623|Vibrionales 135623|Vibrionales G TRAP-type C4-dicarboxylate transport system, large permease component - - - - - - - - - - - - DctM k141_31606_4 298386.PBPRB1729 4.47e-69 214.0 COG3090@1|root,COG3090@2|Bacteria,1RHYR@1224|Proteobacteria,1S7DI@1236|Gammaproteobacteria,1XXS1@135623|Vibrionales 135623|Vibrionales G Tripartite ATP-independent periplasmic transporters, DctQ component - - - - - - - - - - - - DctQ k141_31606_5 1348635.BBJY01000005_gene3346 1.2e-174 494.0 COG1638@1|root,COG1638@2|Bacteria,1N0H9@1224|Proteobacteria,1RRWK@1236|Gammaproteobacteria,1XWAR@135623|Vibrionales 135623|Vibrionales G Bacterial extracellular solute-binding protein, family 7 - - - - - - - - - - - - DctP k141_31606_6 701176.VIBRN418_14681 8.33e-160 452.0 COG3717@1|root,COG3717@2|Bacteria,1MU9D@1224|Proteobacteria,1RPDB@1236|Gammaproteobacteria,1XSKN@135623|Vibrionales 135623|Vibrionales G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate kduI - 5.3.1.17 ko:K01815 ko00040,map00040 - R04383 RC00541 ko00000,ko00001,ko01000 - - - KduI k141_31606_7 223926.28808209 2.88e-271 743.0 COG1062@1|root,COG1062@2|Bacteria,1MUK4@1224|Proteobacteria,1RNQ4@1236|Gammaproteobacteria,1XSME@135623|Vibrionales 135623|Vibrionales C Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily frmA - 1.1.1.1,1.1.1.284 ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 - R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N k141_31606_8 1116375.VEJY3_16011 8.38e-194 538.0 COG0627@1|root,COG0627@2|Bacteria,1MUID@1224|Proteobacteria,1RMR3@1236|Gammaproteobacteria,1XUG1@135623|Vibrionales 135623|Vibrionales S Serine hydrolase involved in the detoxification of formaldehyde yeiG - 3.1.2.12 ko:K01070 ko00680,ko01120,ko01200,map00680,map01120,map01200 - R00527 RC00167,RC00320 ko00000,ko00001,ko01000 - CE1 - Esterase k141_31606_9 1116375.VEJY3_16006 6.55e-73 222.0 COG3915@1|root,COG3915@2|Bacteria,1MZ0E@1224|Proteobacteria,1SCPT@1236|Gammaproteobacteria,1XXIY@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria - - - - - - - - - - - - Oxidored_molyb k141_31606_10 1116375.VEJY3_16001 3.42e-190 536.0 COG2199@1|root,COG2199@2|Bacteria,1MXY1@1224|Proteobacteria,1RXYD@1236|Gammaproteobacteria,1XVDE@135623|Vibrionales 135623|Vibrionales T COG2199 FOG GGDEF domain cdgA - 2.7.7.65 ko:K20956 ko05111,map05111 - - - ko00000,ko00001,ko01000 - - - GGDEF k141_31606_11 1116375.VEJY3_15996 3.31e-171 480.0 COG0561@1|root,COG0561@2|Bacteria,1Q5HK@1224|Proteobacteria,1RQ8H@1236|Gammaproteobacteria,1XTJJ@135623|Vibrionales 135623|Vibrionales S hydrolases of the HAD superfamily - - - - - - - - - - - - Hydrolase_3 k141_31606_12 1116375.VEJY3_15981 0.0 993.0 COG0564@1|root,COG0564@2|Bacteria,1MVJ5@1224|Proteobacteria,1RN61@1236|Gammaproteobacteria,1XSMM@135623|Vibrionales 135623|Vibrionales J COG0564 Pseudouridylate synthases, 23S RNA-specific - - 5.4.99.28,5.4.99.29 ko:K06177 - - - - ko00000,ko01000,ko03009,ko03016 - - - PseudoU_synth_2 k141_35624_1 1123236.KB899376_gene1124 2.82e-40 149.0 COG4242@1|root,COG4242@2|Bacteria,1R6CH@1224|Proteobacteria,1RPCF@1236|Gammaproteobacteria,46AYY@72275|Alteromonadaceae 1236|Gammaproteobacteria PQ COG4242 Cyanophycinase and related exopeptidases - - - - - - - - - - - - - k141_16462_1 1279017.AQYJ01000028_gene2204 2.85e-13 68.6 COG1215@1|root,COG1215@2|Bacteria,1QU4E@1224|Proteobacteria,1S557@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 k141_21095_1 1294265.JCM21738_1461 1.37e-123 365.0 COG5276@1|root,COG5276@2|Bacteria,1UUVN@1239|Firmicutes,4HBJX@91061|Bacilli,1ZE6M@1386|Bacillus 91061|Bacilli S LVIVD repeat - - - - - - - - - - - - LVIVD k141_29549_1 218284.CCDN010000002_gene1979 6.25e-69 212.0 COG1225@1|root,COG1225@2|Bacteria,1V24A@1239|Firmicutes,4HFUX@91061|Bacilli,1ZEQT@1386|Bacillus 91061|Bacilli O Redoxin - - - - - - - - - - - - AhpC-TSA k141_3306_1 340177.Cag_0515 1.45e-30 117.0 COG1091@1|root,COG1091@2|Bacteria,1FD6G@1090|Chlorobi 1090|Chlorobi C Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose - - 1.1.1.133 ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777 RC00182 ko00000,ko00001,ko00002,ko01000 - - - RmlD_sub_bind k141_3306_2 458817.Shal_1487 6.07e-169 476.0 COG1209@1|root,COG1209@2|Bacteria,1MU0X@1224|Proteobacteria,1RMTR@1236|Gammaproteobacteria,2QAWW@267890|Shewanellaceae 1236|Gammaproteobacteria H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis rfbA - 2.7.7.24 ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 M00793 R02328 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase k141_3306_3 1263831.F543_3900 5.67e-222 615.0 COG1088@1|root,COG1088@2|Bacteria,1MU5E@1224|Proteobacteria,1RP7G@1236|Gammaproteobacteria,1Y77C@135625|Pasteurellales 135625|Pasteurellales M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily rfbB GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008460,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0045226,GO:0046379,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 4.2.1.46 ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 M00793 R06513 RC00402 ko00000,ko00001,ko00002,ko01000 - - - GDP_Man_Dehyd k141_3306_4 1178482.BJB45_18540 4.03e-29 126.0 COG3307@1|root,COG3307@2|Bacteria,1RBUE@1224|Proteobacteria,1S3G3@1236|Gammaproteobacteria,1XNU7@135619|Oceanospirillales 135619|Oceanospirillales M O-Antigen ligase - - - ko:K02847 ko00540,ko01100,map00540,map01100 M00080 - - ko00000,ko00001,ko00002,ko01000,ko01005,ko02000 9.B.67.4,9.B.67.5 - - Wzy_C k141_36444_1 1294265.JCM21738_4350 2.95e-124 355.0 COG1658@1|root,COG1658@2|Bacteria,1V3K3@1239|Firmicutes,4HH5Y@91061|Bacilli,1ZFNN@1386|Bacillus 91061|Bacilli J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step rnmV GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043822,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 3.1.26.8 ko:K05985 - - - - ko00000,ko01000 - - - DUF4093,Toprim,Toprim_4 k141_17558_2 1267003.KB911374_gene852 2.89e-06 49.7 COG1564@1|root,COG1564@2|Bacteria,1VA0W@1239|Firmicutes,4HHS1@91061|Bacilli,3F4N8@33958|Lactobacillaceae 91061|Bacilli H thiamine pyrophosphokinase thiN - 2.7.6.2 ko:K00949 ko00730,ko01100,map00730,map01100 - R00619 RC00002,RC00017 ko00000,ko00001,ko01000 - - - TPK_B1_binding,TPK_catalytic k141_10535_1 218284.CCDN010000001_gene1798 2.32e-120 355.0 COG2262@1|root,COG2262@2|Bacteria,1TNZB@1239|Firmicutes,4HACA@91061|Bacilli,1ZBT6@1386|Bacillus 91061|Bacilli S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis hflX - - ko:K03665 - - - - ko00000,ko03009 - - - GTP-bdg_M,GTP-bdg_N,MMR_HSR1 k141_4529_1 935837.JAEK01000020_gene632 3.63e-74 236.0 COG1004@1|root,COG1004@2|Bacteria,1TQFN@1239|Firmicutes,4HADP@91061|Bacilli,1ZAP3@1386|Bacillus 91061|Bacilli M Belongs to the UDP-glucose GDP-mannose dehydrogenase family ywqF - 1.1.1.22 ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 M00014,M00129,M00361,M00362 R00286 RC00291 ko00000,ko00001,ko00002,ko01000 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N k141_15165_1 1429851.X548_09420 9.22e-05 43.5 2BIYM@1|root,32D6Z@2|Bacteria,1NDA6@1224|Proteobacteria,1SRSH@1236|Gammaproteobacteria,1XA6K@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - k141_15165_2 1198452.Jab_2c18310 4.54e-89 277.0 COG1541@1|root,COG1541@2|Bacteria,1PTC8@1224|Proteobacteria 1224|Proteobacteria H AMP-binding enzyme - - 6.2.1.30 ko:K01912 ko00360,ko01120,ko05111,map00360,map01120,map05111 - R02539 RC00004,RC00014 ko00000,ko00001,ko01000 - - - AMP-binding k141_30465_1 42565.FP66_10575 2.26e-135 392.0 COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,1RM89@1236|Gammaproteobacteria,1XHJY@135619|Oceanospirillales 135619|Oceanospirillales L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex mutL - - ko:K03572 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - DNA_mis_repair,HATPase_c_3,MutL_C k141_21096_1 1385514.N782_14880 3.19e-97 298.0 COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,4HAV1@91061|Bacilli,2Y99W@289201|Pontibacillus 91061|Bacilli EH Belongs to the TPP enzyme family - - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N k141_17559_1 223926.28808063 3.52e-135 390.0 COG0026@1|root,COG0026@2|Bacteria,1MU70@1224|Proteobacteria,1RQEI@1236|Gammaproteobacteria,1XU8Y@135623|Vibrionales 135623|Vibrionales F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) purK GO:0003674,GO:0003824,GO:0004638,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.18 ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07404 RC01927 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp k141_28169_1 1294265.JCM21738_2972 7.08e-129 376.0 COG1271@1|root,COG1271@2|Bacteria,1TRH4@1239|Firmicutes,4HA19@91061|Bacilli,1ZBAG@1386|Bacillus 91061|Bacilli C oxidase, subunit ythA - 1.10.3.14 ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - Cyt_bd_oxida_I k141_7968_1 1042377.AFPJ01000020_gene2056 7.59e-187 533.0 COG2067@1|root,COG2067@2|Bacteria,1R3SS@1224|Proteobacteria,1S0X2@1236|Gammaproteobacteria 1236|Gammaproteobacteria I long-chain fatty acid transport protein - - - ko:K06076 - - - - ko00000,ko02000 1.B.9 - - Toluene_X k141_7968_2 1453501.JELR01000001_gene2859 7.22e-138 395.0 COG3637@1|root,COG3637@2|Bacteria,1R3Z1@1224|Proteobacteria,1S22U@1236|Gammaproteobacteria,469TG@72275|Alteromonadaceae 1236|Gammaproteobacteria M Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - - - - - - - - - - - k141_2093_1 866895.HBHAL_1573 1.93e-26 110.0 COG5002@1|root,COG5002@2|Bacteria,1TPPQ@1239|Firmicutes,4HCZW@91061|Bacilli 91061|Bacilli T Histidine kinase - - 2.7.13.3 ko:K07642 ko02020,map02020 M00450,M00645,M00646,M00648 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA k141_13042_2 1279017.AQYJ01000026_gene51 8.58e-17 73.9 2E4VZ@1|root,32ZQ5@2|Bacteria,1N7XP@1224|Proteobacteria,1SCVI@1236|Gammaproteobacteria,468QB@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF3081) - - - - - - - - - - - - DUF3081 k141_31614_1 1279017.AQYJ01000022_gene2721 1.19e-192 563.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria,465ZZ@72275|Alteromonadaceae 1236|Gammaproteobacteria P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec k141_20159_1 223926.28809516 2.47e-183 511.0 COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,1RMK8@1236|Gammaproteobacteria,1Y2HM@135623|Vibrionales 135623|Vibrionales E branched-chain amino acid transport - - - ko:K01996 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran k141_20159_2 1116375.VEJY3_18421 2.07e-94 285.0 COG0683@1|root,COG0683@2|Bacteria,1MV5T@1224|Proteobacteria,1TIWA@1236|Gammaproteobacteria,1XZU0@135623|Vibrionales 135623|Vibrionales E Periplasmic binding protein - - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 k141_33048_1 1116375.VEJY3_12920 1.15e-240 680.0 COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,1RNHV@1236|Gammaproteobacteria,1XVGW@135623|Vibrionales 135623|Vibrionales M Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) mrcB GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.4.1.129,3.4.16.4 ko:K05365 ko00550,map00550 - R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase,UB2H k141_33048_2 1116375.VEJY3_12915 0.0 1288.0 COG1752@1|root,COG4775@1|root,COG1752@2|Bacteria,COG4775@2|Bacteria,1MUM9@1224|Proteobacteria,1RRSK@1236|Gammaproteobacteria,1XTMT@135623|Vibrionales 135623|Vibrionales M esterase of the alpha-beta hydrolase superfamily VP2496 - - ko:K07001 - - - - ko00000 - - - POTRA,Patatin k141_33048_3 1116375.VEJY3_12910 5.21e-283 793.0 COG1049@1|root,COG1049@2|Bacteria,1MVCR@1224|Proteobacteria,1RNMC@1236|Gammaproteobacteria,1XTKU@135623|Vibrionales 135623|Vibrionales C Belongs to the aconitase IPM isomerase family acnB - 4.2.1.3,4.2.1.99 ko:K01682 ko00020,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173 R01324,R01325,R01900,R04425 RC00497,RC00498,RC00618,RC01153 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_2_N,Aconitase_B_N k141_16479_1 1450694.BTS2_3515 5.86e-44 152.0 COG1562@1|root,COG1562@2|Bacteria,1TQHF@1239|Firmicutes,4HA1A@91061|Bacilli,1ZCIV@1386|Bacillus 91061|Bacilli I phytoene crtM - 2.5.1.32,2.5.1.99 ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 M00097 R02065,R04218,R07270,R10177 RC00362,RC01101,RC02869 ko00000,ko00001,ko00002,ko01000,ko01006 - - - SQS_PSY k141_5935_1 333138.LQ50_18720 1.9e-33 124.0 COG1354@1|root,COG1354@2|Bacteria,1TRW3@1239|Firmicutes,4HA6Q@91061|Bacilli,1ZDD6@1386|Bacillus 91061|Bacilli D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves scpA GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K05896 - - - - ko00000,ko03036 - - - SMC_ScpA k141_5935_2 292.DM42_2991 3.54e-22 97.8 COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,2VIEY@28216|Betaproteobacteria,1K18D@119060|Burkholderiaceae 28216|Betaproteobacteria J Tryptophanyl-tRNA synthetase trpS - 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1b k141_29583_1 1340434.AXVA01000012_gene3022 2.89e-147 422.0 COG1960@1|root,COG1960@2|Bacteria,1TSN3@1239|Firmicutes,4HB0T@91061|Bacilli,1ZDR4@1386|Bacillus 91061|Bacilli I Acyl-CoA dehydrogenase, N-terminal domain - - 1.3.8.7 ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_2094_1 1408419.JHYG01000003_gene251 2.28e-08 54.3 COG0245@1|root,COG0245@2|Bacteria,1MVHA@1224|Proteobacteria,2TRQC@28211|Alphaproteobacteria,2JPA7@204441|Rhodospirillales 204441|Rhodospirillales I Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) ispDF - 2.7.7.60,4.6.1.12 ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05633,R05637 RC00002,RC01440 ko00000,ko00001,ko00002,ko01000 - - - IspD,YgbB k141_2094_2 1121272.KB903254_gene6689 2.98e-38 140.0 COG0498@1|root,COG0498@2|Bacteria,2GNZD@201174|Actinobacteria,4DCA6@85008|Micromonosporales 201174|Actinobacteria E Pyridoxal-phosphate dependent enzyme - - 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 - - - PALP k141_24875_1 1209072.ALBT01000033_gene1725 5.49e-38 145.0 COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,1RPV3@1236|Gammaproteobacteria,1FGTE@10|Cellvibrio 1236|Gammaproteobacteria NU Neisseria PilC beta-propeller domain - - - ko:K02674 - - - - ko00000,ko02035,ko02044 - - - Neisseria_PilC,PA14 k141_3327_1 1453501.JELR01000001_gene2853 7.98e-84 263.0 COG0477@1|root,COG2814@2|Bacteria,1MVKJ@1224|Proteobacteria,1RMHJ@1236|Gammaproteobacteria,464EA@72275|Alteromonadaceae 1236|Gammaproteobacteria EGP Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family xylE GO:0003674,GO:0005215,GO:0005351,GO:0005402,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0008643,GO:0015075,GO:0015077,GO:0015078,GO:0015144,GO:0015145,GO:0015146,GO:0015148,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015519,GO:0015672,GO:0015749,GO:0015750,GO:0015753,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034219,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 - ko:K05548,ko:K08138,ko:K08139 ko04113,map04113 - - - ko00000,ko00001,ko02000 2.A.1.1,2.A.1.1.3,2.A.1.15 - iECIAI1_1343.ECIAI1_4259,iECSE_1348.ECSE_4322 Sugar_tr k141_20160_1 1294265.JCM21738_469 1.48e-113 328.0 COG1295@1|root,COG1295@2|Bacteria,1U7HM@1239|Firmicutes,4H9MJ@91061|Bacilli,1ZCAD@1386|Bacillus 91061|Bacilli S Belongs to the UPF0761 family yihY - - ko:K07058 - - - - ko00000 - - - Virul_fac_BrkB k141_33049_1 189425.PGRAT_19210 1.89e-18 89.7 COG4926@1|root,COG4926@2|Bacteria,1TQHW@1239|Firmicutes,4HFA8@91061|Bacilli,26VV6@186822|Paenibacillaceae 91061|Bacilli S Prophage endopeptidase tail - - - - - - - - - - - - Prophage_tail k141_5936_1 1385513.N780_17640 3.1e-103 326.0 COG2273@1|root,COG2273@2|Bacteria,1TR5U@1239|Firmicutes,4HB9D@91061|Bacilli,2YB4A@289201|Pontibacillus 91061|Bacilli G PFAM glycoside hydrolase family 16 - - - - - - - - - - - - CBM_4_9,Glyco_hydro_16,SLH k141_30473_2 1177179.A11A3_14912 6.06e-94 280.0 COG0625@1|root,COG0625@2|Bacteria,1RA05@1224|Proteobacteria,1S3YW@1236|Gammaproteobacteria,1XJTU@135619|Oceanospirillales 135619|Oceanospirillales O Glutathione S-transferase, N-terminal domain - - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_N_3,HTH_11 k141_30473_3 1173028.ANKO01000130_gene1847 3.1e-129 387.0 COG0438@1|root,COG0438@2|Bacteria,1G3II@1117|Cyanobacteria,1H9ER@1150|Oscillatoriales 1117|Cyanobacteria M glycosyl transferase group 1 - - 2.4.1.11 ko:K16150 ko00500,ko01100,map00500,map01100 - R00292 RC00005 ko00000,ko00001,ko01000,ko01003 - GT4 - Glycos_transf_1 k141_24876_1 1304875.JAFZ01000001_gene1386 0.000298 47.8 COG0653@1|root,COG0653@2|Bacteria,3TA76@508458|Synergistetes 508458|Synergistetes U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA - - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW k141_20161_1 441769.ABFU01000049_gene3702 5.78e-51 171.0 COG0672@1|root,COG0672@2|Bacteria,1TQIA@1239|Firmicutes,4HCJZ@91061|Bacilli,1ZDYA@1386|Bacillus 91061|Bacilli P COG0672 High-affinity Fe2 Pb2 permease - - - ko:K07243 - - - - ko00000,ko02000 2.A.108.1,2.A.108.2 - - FTR1 k141_29584_1 218284.CCDN010000001_gene962 1.77e-155 446.0 COG0439@1|root,COG0439@2|Bacteria,1TP16@1239|Firmicutes,4HARK@91061|Bacilli,1ZC56@1386|Bacillus 91061|Bacilli I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism accC - 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 k141_16480_2 218284.CCDN010000002_gene2187 1.32e-114 328.0 COG1225@1|root,COG1225@2|Bacteria,1V4YG@1239|Firmicutes,4HHP6@91061|Bacilli,1ZEZC@1386|Bacillus 91061|Bacilli O Redoxin - - - - - - - - - - - - AhpC-TSA k141_16480_3 218284.CCDN010000002_gene2186 1.35e-10 60.5 COG3173@1|root,COG3173@2|Bacteria,1V2AK@1239|Firmicutes,4HFXB@91061|Bacilli,1ZQ72@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF1679) - - - - - - - - - - - - APH k141_15168_1 1279017.AQYJ01000021_gene2781 0.0 933.0 COG3127@1|root,COG3127@2|Bacteria,1MU9R@1224|Proteobacteria,1RM8Y@1236|Gammaproteobacteria,4654Y@72275|Alteromonadaceae 1236|Gammaproteobacteria Q ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component ybbP GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX k141_13045_1 1453501.JELR01000005_gene1616 1.54e-135 409.0 COG3391@1|root,COG3391@2|Bacteria,1RA6R@1224|Proteobacteria,1SE8J@1236|Gammaproteobacteria 1236|Gammaproteobacteria S amine dehydrogenase activity - - - - - - - - - - - - - k141_21108_1 1294265.JCM21738_4962 6.22e-99 301.0 COG0665@1|root,COG0723@1|root,COG0665@2|Bacteria,COG0723@2|Bacteria,1TR1R@1239|Firmicutes,4H9V8@91061|Bacilli,1ZC19@1386|Bacillus 91061|Bacilli CE COG0665 Glycine D-amino acid oxidases (deaminating) yhfW GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0044424,GO:0044464,GO:0055114 - - - - - - - - - - DAO,Rieske k141_5938_1 234267.Acid_1914 2.51e-36 137.0 COG0304@1|root,COG0304@2|Bacteria,3Y43C@57723|Acidobacteria 57723|Acidobacteria IQ Beta-ketoacyl synthase, C-terminal domain - - 2.3.1.179 ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt k141_28172_1 1042377.AFPJ01000043_gene830 1.31e-15 77.0 COG0560@1|root,COG0560@2|Bacteria,1MWA3@1224|Proteobacteria,1RNJE@1236|Gammaproteobacteria,4647E@72275|Alteromonadaceae 1236|Gammaproteobacteria E phosphoserine phosphatase serB GO:0000287,GO:0001505,GO:0003674,GO:0003824,GO:0004647,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006563,GO:0006564,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0017144,GO:0019752,GO:0042133,GO:0042136,GO:0042578,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046872,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.3 ko:K01079 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R00582 RC00017 ko00000,ko00001,ko00002,ko01000,ko01009 - - iE2348C_1286.E2348C_4686,iEC042_1314.EC042_4885,iECO26_1355.ECO26_5594,iECSF_1327.ECSF_4321,iECUMN_1333.ECUMN_5012,iETEC_1333.ETEC_4743,iPC815.YPO0442,iUMNK88_1353.UMNK88_5307 ACT_6,HAD,Hydrolase k141_28172_2 1453501.JELR01000002_gene1389 1.99e-74 233.0 COG2114@1|root,COG2114@2|Bacteria,1N41U@1224|Proteobacteria,1SB9D@1236|Gammaproteobacteria,469AN@72275|Alteromonadaceae 1236|Gammaproteobacteria T Pfam Adenylate and Guanylate cyclase catalytic domain - - - - - - - - - - - - - k141_29586_1 218284.CCDN010000005_gene3438 4.32e-95 289.0 COG2056@1|root,COG2056@2|Bacteria,1TSRY@1239|Firmicutes,4HBK6@91061|Bacilli,1ZB9I@1386|Bacillus 91061|Bacilli S antiporter yuiF - - ko:K07084 - - - - ko00000,ko02000 2.A.8.1.12 - iSB619.SA_RS04585 Na_H_antiport_2,Na_H_antiporter k141_31615_1 218284.CCDN010000008_gene4265 5.99e-161 462.0 COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,4HAEE@91061|Bacilli,1ZBHY@1386|Bacillus 91061|Bacilli E Cysteine desulfurase iscS2 - 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - - Aminotran_5 k141_33051_1 1453501.JELR01000002_gene50 4.06e-64 214.0 COG1505@1|root,COG1505@2|Bacteria,1NZ7N@1224|Proteobacteria,1T1KJ@1236|Gammaproteobacteria,46621@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG1505 Serine proteases of the peptidase family S9A - - 3.4.21.26 ko:K01322 ko04614,map04614 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S9,Peptidase_S9_N k141_37736_1 1444306.JFZC01000023_gene2516 1.27e-19 85.1 COG0681@1|root,COG0681@2|Bacteria,1V2BJ@1239|Firmicutes,4HGCB@91061|Bacilli,26NXA@186821|Sporolactobacillaceae 91061|Bacilli U Belongs to the peptidase S26 family spsB - 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24 k141_37736_2 218284.CCDN010000001_gene1674 1.64e-26 104.0 COG0662@1|root,COG0662@2|Bacteria,1V3H4@1239|Firmicutes,4HH1K@91061|Bacilli,1ZFFQ@1386|Bacillus 91061|Bacilli G Cupin domain - - - - - - - - - - - - Cupin_2 k141_17587_1 1453501.JELR01000002_gene240 1.15e-109 322.0 COG1210@1|root,COG1210@2|Bacteria,1MV5F@1224|Proteobacteria,1RNDX@1236|Gammaproteobacteria,4650D@72275|Alteromonadaceae 1236|Gammaproteobacteria M UTP-glucose-1-phosphate uridylyltransferase galU - 2.7.7.9 ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 M00129,M00361,M00362,M00549 R00289 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase k141_17587_2 999141.GME_02810 6.11e-200 563.0 COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,1RMVW@1236|Gammaproteobacteria,1XIGZ@135619|Oceanospirillales 135619|Oceanospirillales M Belongs to the UDP-glucose GDP-mannose dehydrogenase family - - 1.1.1.22 ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 M00014,M00129,M00361,M00362 R00286 RC00291 ko00000,ko00001,ko00002,ko01000 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N k141_17587_3 1279017.AQYJ01000023_gene3089 2.58e-258 719.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,4643Q@72275|Alteromonadaceae 1236|Gammaproteobacteria JKL DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation deaD GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003725,GO:0003727,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006417,GO:0006725,GO:0006807,GO:0006950,GO:0006996,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009266,GO:0009314,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009987,GO:0010468,GO:0010501,GO:0010556,GO:0010557,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019439,GO:0022607,GO:0022613,GO:0022618,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031330,GO:0032268,GO:0032270,GO:0033554,GO:0033592,GO:0034248,GO:0034250,GO:0034622,GO:0034641,GO:0034655,GO:0042254,GO:0042255,GO:0042273,GO:0042623,GO:0043170,GO:0043487,GO:0043488,GO:0043489,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045934,GO:0046483,GO:0046700,GO:0048255,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0061013,GO:0065003,GO:0065007,GO:0065008,GO:0070035,GO:0070417,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097617,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902369,GO:1902373,GO:1903311,GO:1903312,GO:2000112 3.6.4.13 ko:K05592 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,DEADboxA,DbpA,Helicase_C k141_24880_1 218284.CCDN010000001_gene981 3.62e-102 302.0 COG0280@1|root,COG0280@2|Bacteria,1TRQU@1239|Firmicutes,4HBSK@91061|Bacilli,1ZC49@1386|Bacillus 91061|Bacilli C phosphate butyryltransferase ptb - 2.3.1.19 ko:K00634 ko00650,ko01100,map00650,map01100 - R01174 RC00004,RC02816 ko00000,ko00001,ko01000 - - iYO844.BSU24090 PTA_PTB k141_16481_1 1279017.AQYJ01000023_gene3161 5.63e-172 497.0 COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,1RNI4@1236|Gammaproteobacteria,4664Q@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1008 NADH ubiquinone oxidoreductase subunit 4 (chain M) nuoM - 1.6.5.3 ko:K00342 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_M k141_37737_1 1499968.TCA2_4879 1.12e-26 110.0 COG0642@1|root,COG2205@2|Bacteria,1V10X@1239|Firmicutes,4HB4P@91061|Bacilli,26SCI@186822|Paenibacillaceae 91061|Bacilli T Histidine kinase hssS - - - - - - - - - - - HAMP,HATPase_c,HisKA k141_13046_1 1294265.JCM21738_2036 2.09e-104 304.0 2E7KE@1|root,3322G@2|Bacteria,1VG6C@1239|Firmicutes,4HNMG@91061|Bacilli,1ZH76@1386|Bacillus 91061|Bacilli S Stage III sporulation protein AF (Spore_III_AF) spoIIIAF - - ko:K06395 - - - - ko00000 - - - Spore_III_AF k141_13046_2 1294265.JCM21738_2035 1.63e-53 172.0 2E6BB@1|root,330Z5@2|Bacteria,1VF3M@1239|Firmicutes,4HH7J@91061|Bacilli,1ZEMQ@1386|Bacillus 91061|Bacilli S stage III sporulation protein AG spoIIIAG - - ko:K06396 - - - - ko00000 - - - - k141_15169_1 1453501.JELR01000001_gene2605 1.22e-112 345.0 COG0210@1|root,COG0210@2|Bacteria,1MXWE@1224|Proteobacteria,1RP5D@1236|Gammaproteobacteria,466UN@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG0210 Superfamily I DNA and RNA helicases uvrD-2 - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C k141_35643_1 754436.JCM19237_1038 1.3e-72 231.0 COG0823@1|root,COG0823@2|Bacteria,1R4CN@1224|Proteobacteria,1S0NH@1236|Gammaproteobacteria 1236|Gammaproteobacteria U Involved in the tonB-independent uptake of proteins - - - - - - - - - - - - PD40 k141_35643_2 1408428.JNJP01000053_gene2422 5.91e-13 79.0 COG2199@1|root,COG4191@1|root,COG2199@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,43D3P@68525|delta/epsilon subdivisions,2X8AF@28221|Deltaproteobacteria,2MGYX@213115|Desulfovibrionales 28221|Deltaproteobacteria T Cache domain - - - - - - - - - - - - GGDEF,HAMP,PAS_3,dCache_1 k141_24882_1 218284.CCDN010000007_gene3804 7.54e-54 178.0 COG0668@1|root,COG0668@2|Bacteria,1TR9Z@1239|Firmicutes,4HCB8@91061|Bacilli,1ZCW4@1386|Bacillus 91061|Bacilli M Mechanosensitive ion channel ykuT - - ko:K22044 - - - - ko00000,ko02000 1.A.23.3 - - MS_channel k141_3330_1 42565.FP66_10245 1.92e-71 222.0 COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,1RN7F@1236|Gammaproteobacteria,1XHHX@135619|Oceanospirillales 135619|Oceanospirillales J Responsible for synthesis of pseudouridine from uracil rluD - 5.4.99.23 ko:K06180 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 k141_16482_1 1385511.N783_12215 6.35e-22 94.0 COG0843@1|root,COG0843@2|Bacteria,1TPZC@1239|Firmicutes,4HAHT@91061|Bacilli,2Y9CW@289201|Pontibacillus 91061|Bacilli C Belongs to the heme-copper respiratory oxidase family - - 1.9.3.1 ko:K02274 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6 - - COX1 k141_16482_2 1385511.N783_12220 6.76e-55 178.0 COG1999@1|root,COG1999@2|Bacteria,1V20G@1239|Firmicutes,4HG53@91061|Bacilli 91061|Bacilli S 'protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems' - - - ko:K07152 - - - - ko00000,ko03029 - - - SCO1-SenC k141_21109_1 377629.TERTU_4455 2.86e-51 173.0 COG3547@1|root,COG3547@2|Bacteria,1MXKJ@1224|Proteobacteria,1RSCP@1236|Gammaproteobacteria,2PQC7@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria L Transposase Z012_08285 - - ko:K07486 - - - - ko00000 - - - DEDD_Tnp_IS110,Transposase_20 k141_21109_2 225849.swp_0862 1.37e-33 126.0 COG3547@1|root,COG3547@2|Bacteria,1MXKJ@1224|Proteobacteria,1RSCP@1236|Gammaproteobacteria,2QBDW@267890|Shewanellaceae 1236|Gammaproteobacteria L Transposase IS116/IS110/IS902 family Z012_08285 - - ko:K07486 - - - - ko00000 - - - DEDD_Tnp_IS110,Transposase_20 k141_29588_1 265729.GS18_0205935 6.5e-44 155.0 COG0277@1|root,COG0277@2|Bacteria,1TPBC@1239|Firmicutes,4H9UU@91061|Bacilli,1ZCHD@1386|Bacillus 91061|Bacilli C FAD linked oxidases, C-terminal domain glcD - 1.1.3.15 ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001,ko01000 - - - FAD-oxidase_C,FAD_binding_4 k141_24883_1 997296.PB1_06457 3.28e-18 81.6 29HQ2@1|root,304MB@2|Bacteria,1V21Z@1239|Firmicutes,4HG8B@91061|Bacilli,1ZC8S@1386|Bacillus 91061|Bacilli S Spore gernimation protein gerD - - ko:K06294 - - - - ko00000 - - - - k141_24883_2 1294265.JCM21738_5484 8.38e-128 366.0 COG2194@1|root,COG2194@2|Bacteria,1UZ64@1239|Firmicutes,4HF6P@91061|Bacilli,1ZQJH@1386|Bacillus 91061|Bacilli S KinB-signalling pathway activation in sporulation - - - ko:K06349 - - - - ko00000 - - - KbaA k141_1184_1 247633.GP2143_08859 3.66e-70 221.0 COG3975@1|root,COG3975@2|Bacteria,1N69B@1224|Proteobacteria,1RY45@1236|Gammaproteobacteria,1JA09@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - Peptidase_M61 k141_1184_2 1453501.JELR01000002_gene329 4.72e-151 440.0 COG3063@1|root,COG3063@2|Bacteria,1R0M2@1224|Proteobacteria,1T4K4@1236|Gammaproteobacteria,46DCA@72275|Alteromonadaceae 1236|Gammaproteobacteria NU Tetratricopeptide repeat - - - - - - - - - - - - TPR_16,TPR_8,Transglut_core k141_19086_1 458233.MCCL_0341 2.66e-25 103.0 COG4132@1|root,COG4132@2|Bacteria,1TRF0@1239|Firmicutes,4HCV5@91061|Bacilli 91061|Bacilli P ABC transporter (permease) - - - ko:K02054 ko02024,map02024 M00193 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11 - - BPD_transp_1 k141_19086_2 1121334.KB911070_gene1279 8.4e-11 62.4 COG1524@1|root,COG1524@2|Bacteria,1TR0T@1239|Firmicutes,24G1T@186801|Clostridia,3WISV@541000|Ruminococcaceae 186801|Clostridia S Type I phosphodiesterase / nucleotide pyrophosphatase - - - - - - - - - - - - Phosphodiest k141_13172_2 44454.NF84_20245 1.95e-07 55.1 COG1835@1|root,COG1835@2|Bacteria,2GS8J@201174|Actinobacteria,234CQ@1762|Mycobacteriaceae 201174|Actinobacteria I Acyltransferase family - - - - - - - - - - - - Acyl_transf_3 k141_13172_3 1149133.ppKF707_1109 7.59e-14 80.5 COG2207@1|root,COG2207@2|Bacteria,1MX23@1224|Proteobacteria,1TBT1@1236|Gammaproteobacteria,1YIX9@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria K Arabinose-binding domain of AraC transcription regulator, N-term - - - - - - - - - - - - Arabinose_bd,HTH_18 k141_15548_1 218284.CCDN010000005_gene3229 3.02e-117 370.0 COG1074@1|root,COG1074@2|Bacteria,1TQ35@1239|Firmicutes,4HA64@91061|Bacilli,1ZBG6@1386|Bacillus 91061|Bacilli L ATP-dependent helicase nuclease subunit A addA GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 3.6.4.12 ko:K16898 - - - - ko00000,ko01000,ko03400 - - - PDDEXK_1,UvrD-helicase,UvrD_C k141_15548_2 218284.CCDN010000005_gene3230 4.97e-33 115.0 COG1403@1|root,COG1403@2|Bacteria,1VFR5@1239|Firmicutes,4HQB5@91061|Bacilli,1ZICY@1386|Bacillus 91061|Bacilli V COG1403 Restriction endonuclease yisB - - - - - - - - - - - HNH k141_33361_1 1453501.JELR01000002_gene492 1.3e-06 48.5 COG3038@1|root,COG3038@2|Bacteria,1MZ7X@1224|Proteobacteria,1S3RF@1236|Gammaproteobacteria,467A7@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG3038 Cytochrome B561 yceJ GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K12262 - - - - ko00000 - - - Ni_hydr_CYTB k141_33361_2 1042377.AFPJ01000048_gene2675 3.01e-79 238.0 COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,1S24R@1236|Gammaproteobacteria,466CX@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the UPF0312 family yceI - - - - - - - - - - - YceI k141_28620_1 1294265.JCM21738_2456 6.37e-36 126.0 2EMN9@1|root,33FAK@2|Bacteria,1VYRX@1239|Firmicutes,4HYX3@91061|Bacilli,1ZDD5@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_9579_1 1279017.AQYJ01000018_gene827 4.89e-149 466.0 COG0770@1|root,COG2843@1|root,COG0770@2|Bacteria,COG2843@2|Bacteria,1QTSF@1224|Proteobacteria,1RMGD@1236|Gammaproteobacteria,464UU@72275|Alteromonadaceae 1236|Gammaproteobacteria M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein - - - - - - - - - - - - Mur_ligase_C,Mur_ligase_M,PGA_cap k141_9579_2 1279017.AQYJ01000018_gene828 1.36e-56 182.0 COG3751@1|root,COG3751@2|Bacteria,1NAUK@1224|Proteobacteria,1S2G4@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Putative 2OG-Fe(II) oxygenase - - - - - - - - - - - - 2OG-FeII_Oxy_5 k141_21492_1 1309583.M4W9Q4_9CAUD 8.29e-56 196.0 4QBPB@10239|Viruses,4QWHE@35237|dsDNA viruses no RNA stage,4QPPH@28883|Caudovirales,4QNRH@10744|Podoviridae 10744|Podoviridae - - - GO:0005575,GO:0019012,GO:0044423,GO:0098015 - - - - - - - - - - - k141_30997_1 1294265.JCM21738_2698 2.7e-135 387.0 COG1609@1|root,COG1609@2|Bacteria,1TPZM@1239|Firmicutes,4H9ZT@91061|Bacilli,1ZB2U@1386|Bacillus 91061|Bacilli K Transcriptional regulator malR - - - - - - - - - - - LacI,Peripla_BP_3 k141_30997_2 1294265.JCM21738_2697 6.89e-102 308.0 COG0366@1|root,COG0366@2|Bacteria,1TSVI@1239|Firmicutes,4HCV2@91061|Bacilli,1ZDR6@1386|Bacillus 91061|Bacilli G Alpha amylase, catalytic domain - - 3.2.1.1 ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 - R02108,R02112,R11262 - ko00000,ko00001,ko01000 - GH13 - Alpha-amylase k141_13174_1 1453501.JELR01000001_gene1905 4.01e-121 353.0 COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,1RNPX@1236|Gammaproteobacteria,464Y1@72275|Alteromonadaceae 1236|Gammaproteobacteria P Belongs to the ABC transporter superfamily - - 3.6.3.30 ko:K02010 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.10 - - ABC_tran,TOBE_2 k141_13174_2 1042377.AFPJ01000037_gene2936 1.33e-08 55.5 COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,1RP55@1236|Gammaproteobacteria,465RX@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1178 ABC-type Fe3 transport system, permease component sfuB - - ko:K02011 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - BPD_transp_1 k141_19087_1 265729.GS18_0216410 2.72e-18 81.6 COG0778@1|root,COG0778@2|Bacteria,1UB8S@1239|Firmicutes,4HEGP@91061|Bacilli,1ZBQ3@1386|Bacillus 91061|Bacilli C Oxidoreductase nfrA1 - 1.5.1.38 ko:K19285 ko00740,ko01100,map00740,map01100 - R05706 RC00126 ko00000,ko00001,ko01000 - - - Nitroreductase k141_19087_2 218284.CCDN010000001_gene1961 9.83e-66 202.0 COG0219@1|root,COG0219@2|Bacteria,1V3GW@1239|Firmicutes,4HFNY@91061|Bacilli,1ZFKH@1386|Bacillus 91061|Bacilli J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily cspR - 2.1.1.207 ko:K03216 - - - - ko00000,ko01000,ko03016 - - - SpoU_methylase k141_27388_1 218284.CCDN010000005_gene3170 1.32e-134 389.0 COG0760@1|root,COG0760@2|Bacteria,1TX3R@1239|Firmicutes,4HC85@91061|Bacilli,1ZC6P@1386|Bacillus 91061|Bacilli M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins prsA - 5.2.1.8 ko:K01802,ko:K07533 - - - - ko00000,ko01000,ko03110 - - - Rotamase_3,Trigger_C k141_26240_1 218284.CCDN010000001_gene780 9e-36 125.0 COG3170@1|root,COG3170@2|Bacteria 2|Bacteria NU translation initiation factor activity fimV - - ko:K08086,ko:K15845 ko05120,map05120 - - - ko00000,ko00001 - - - LysM,TPR_19 k141_11950_1 218284.CCDN010000008_gene4224 1.45e-204 570.0 COG1605@1|root,COG2876@1|root,COG1605@2|Bacteria,COG2876@2|Bacteria,1TP61@1239|Firmicutes,4HB03@91061|Bacilli,1ZB0X@1386|Bacillus 91061|Bacilli E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate aroA - 2.5.1.54,5.4.99.5 ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022,M00024,M00025 R01715,R01826 RC00435,RC03116 ko00000,ko00001,ko00002,ko01000 - - - CM_2,DAHP_synth_1 k141_13175_1 218284.CCDN010000001_gene803 1.99e-98 299.0 COG0697@1|root,COG0697@2|Bacteria,1TP7K@1239|Firmicutes,4HBWN@91061|Bacilli,1ZAS9@1386|Bacillus 91061|Bacilli EG Bacillus/Clostridium GerA spore germination protein spoVAF - - ko:K06408 - - - - ko00000 - - - GerA k141_6027_1 349521.HCH_04087 3.18e-135 406.0 COG1298@1|root,COG1298@2|Bacteria,1MUF3@1224|Proteobacteria,1RMSM@1236|Gammaproteobacteria,1XH92@135619|Oceanospirillales 135619|Oceanospirillales N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin - - - ko:K02400 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 - - FHIPEP k141_6027_2 1101195.Meth11DRAFT_1124 5.7e-62 207.0 COG1377@1|root,COG1377@2|Bacteria,1MUWI@1224|Proteobacteria,2VIH0@28216|Betaproteobacteria,2KMIP@206350|Nitrosomonadales 28216|Betaproteobacteria N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin hrcU - - ko:K02401,ko:K03229,ko:K22510 ko02040,ko03070,map02040,map03070 M00332,M00542,M00660 - - ko00000,ko00001,ko00002,ko02035,ko02044 3.A.6.1,3.A.6.2,3.A.6.3 - - Bac_export_2 k141_9580_2 1453501.JELR01000002_gene1142 4.51e-05 44.7 COG1349@1|root,COG1349@2|Bacteria,1MUJG@1224|Proteobacteria,1RNW4@1236|Gammaproteobacteria,465X4@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG1349 Transcriptional regulators of sugar metabolism glmR - - - - - - - - - - - DeoRC,HTH_DeoR k141_15549_1 1453501.JELR01000002_gene499 0.000647 43.1 COG0454@1|root,COG0456@2|Bacteria,1RHB7@1224|Proteobacteria,1S3TD@1236|Gammaproteobacteria,467KA@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases ectA GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016407,GO:0016740,GO:0016746,GO:0016747,GO:0018130,GO:0019491,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0042399,GO:0043170,GO:0043412,GO:0043436,GO:0043543,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.3.1.178 ko:K06718 ko00260,ko01100,ko01120,map00260,map01100,map01120 M00033 R06978 RC00004,RC00096 ko00000,ko00001,ko00002,ko01000 - - - Acetyltransf_1 k141_19088_1 1042377.AFPJ01000009_gene269 1.23e-55 187.0 COG1115@1|root,COG1115@2|Bacteria,1MUI3@1224|Proteobacteria,1RMNF@1236|Gammaproteobacteria,464HE@72275|Alteromonadaceae 1236|Gammaproteobacteria E alanine symporter yaaJ GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03310 - - - - ko00000 2.A.25 - iEcE24377_1341.EcE24377A_0007 Na_Ala_symp k141_30998_1 1238184.CM001792_gene3474 1.22e-34 121.0 2CBXG@1|root,32RUA@2|Bacteria,1VDAH@1239|Firmicutes,4HN5Q@91061|Bacilli,23N2I@182709|Oceanobacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_26241_2 218284.CCDN010000001_gene693 2.74e-58 181.0 COG3906@1|root,COG3906@2|Bacteria,1VAPW@1239|Firmicutes,4HKV7@91061|Bacilli,1ZI20@1386|Bacillus 91061|Bacilli S Belongs to the UPF0473 family yrzB - - - - - - - - - - - DUF1292 k141_29783_2 1294265.JCM21738_3268 7.37e-97 285.0 COG0702@1|root,COG0702@2|Bacteria,1TS7J@1239|Firmicutes,4HFT3@91061|Bacilli,1ZGA3@1386|Bacillus 91061|Bacilli GM NAD(P)H-binding yheG - - - - - - - - - - - NAD_binding_10 k141_4843_2 1042377.AFPJ01000007_gene1898 8.11e-51 172.0 COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,1RNMZ@1236|Gammaproteobacteria,46547@72275|Alteromonadaceae 1236|Gammaproteobacteria H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein apbE GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016740,GO:0017013,GO:0019538,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0031975,GO:0036094,GO:0036211,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0071944,GO:0071949,GO:0097159,GO:0098552,GO:0098567,GO:1901265,GO:1901363,GO:1901564 2.7.1.180 ko:K03734 - - - - ko00000,ko01000 - - - ApbE k141_27389_1 218284.CCDN010000002_gene2277 1.04e-65 203.0 2D0AC@1|root,32T87@2|Bacteria,1V6E3@1239|Firmicutes,4HIHJ@91061|Bacilli,1ZHXF@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_13176_1 1294265.JCM21738_5071 5.44e-22 87.4 COG0457@1|root,COG0457@2|Bacteria,1V1HX@1239|Firmicutes,4HG5V@91061|Bacilli,1ZCPW@1386|Bacillus 91061|Bacilli S COG0457 FOG TPR repeat yrrB - - - - - - - - - - - TPR_1,TPR_16,TPR_2,TPR_6,TPR_8 k141_13176_2 1294265.JCM21738_5070 2.73e-104 323.0 COG0507@1|root,COG0507@2|Bacteria,1TPZH@1239|Firmicutes,4HATQ@91061|Bacilli,1ZAYS@1386|Bacillus 91061|Bacilli L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity recD2 - 3.1.11.5 ko:K03581 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_30,HHH_4,HHH_5,UvrD_C_2 k141_34558_1 1042377.AFPJ01000007_gene1824 5.67e-41 144.0 COG0798@1|root,COG0798@2|Bacteria,1MUXY@1224|Proteobacteria,1RP2I@1236|Gammaproteobacteria,46446@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0798 Arsenite efflux pump ACR3 and related permeases arsB - - ko:K03325 - - - - ko00000,ko02000 2.A.59 - - SBF k141_34558_2 1298865.H978DRAFT_2462 3.09e-47 156.0 COG0394@1|root,COG0394@2|Bacteria,1MWYQ@1224|Proteobacteria,1S2YD@1236|Gammaproteobacteria,466V8@72275|Alteromonadaceae 1236|Gammaproteobacteria T Belongs to the low molecular weight phosphotyrosine protein phosphatase family - - 1.20.4.1 ko:K03741 - - - - ko00000,ko01000 - - - LMWPc k141_6028_1 218284.CCDN010000001_gene1229 4.86e-97 290.0 COG1876@1|root,COG1876@2|Bacteria,1V1F7@1239|Firmicutes,4HBR1@91061|Bacilli,1ZCAG@1386|Bacillus 91061|Bacilli M D-alanyl-D-alanine carboxypeptidase yodJ - 3.4.17.14 ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 M00651 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 - - - VanY k141_14355_2 203122.Sde_1930 6.23e-92 296.0 COG0845@1|root,COG5569@1|root,COG0845@2|Bacteria,COG5569@2|Bacteria,1MVAS@1224|Proteobacteria,1RPBZ@1236|Gammaproteobacteria,464X2@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family cusB - - ko:K07798 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.6.1.4,8.A.1 - - CusF_Ec,HlyD_D23,HlyD_D4 k141_17937_2 1279017.AQYJ01000019_gene1485 2.32e-43 152.0 COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria,46552@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ Belongs to the beta-ketoacyl-ACP synthases family fabB - 2.3.1.41 ko:K00647 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt k141_3676_3 1048339.KB913029_gene5047 8.11e-15 80.1 COG0739@1|root,COG0739@2|Bacteria,2GXEC@201174|Actinobacteria,4EW3Z@85013|Frankiales 201174|Actinobacteria M Evidence 2a Function of homologous gene experimentally demonstrated in an other organism envC - - ko:K21471 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_M23 k141_36909_1 1116375.VEJY3_23311 5.89e-245 689.0 COG0457@1|root,COG2304@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,1MW51@1224|Proteobacteria,1RMD3@1236|Gammaproteobacteria,1XVCX@135623|Vibrionales 135623|Vibrionales S protein containing a von Willebrand factor type A (vWA) domain - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - TPR_1,TPR_19,TPR_2,VWA_2 k141_36909_2 223926.28809856 3.39e-38 135.0 COG2304@1|root,COG2304@2|Bacteria,1MXQ7@1224|Proteobacteria,1RMDX@1236|Gammaproteobacteria,1XU2A@135623|Vibrionales 135623|Vibrionales S protein containing a von Willebrand factor type A (vWA) domain - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - VWA k141_34579_1 218284.CCDN010000001_gene509 4.29e-133 386.0 COG0281@1|root,COG0281@2|Bacteria,1TPJ3@1239|Firmicutes,4H9WR@91061|Bacilli,1ZBAH@1386|Bacillus 91061|Bacilli C Malate dehydrogenase ytsJ - 1.1.1.38 ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 - R00214 RC00105 ko00000,ko00001,ko01000 - - - Malic_M,malic k141_19101_1 598467.BrE312_4100 3.86e-30 113.0 COG3384@1|root,COG3384@2|Bacteria,1MXJZ@1224|Proteobacteria,1RR5P@1236|Gammaproteobacteria 1236|Gammaproteobacteria S dioxygenase ygiD GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0046566,GO:0051213,GO:0055114 - ko:K15777 ko00965,map00965 - R08836 RC00387 ko00000,ko00001,ko01000 - - - LigB k141_19101_2 757424.Hsero_2126 5.29e-55 180.0 COG1182@1|root,COG1182@2|Bacteria,1P59R@1224|Proteobacteria,2VK5E@28216|Betaproteobacteria,475MK@75682|Oxalobacteraceae 28216|Betaproteobacteria C Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity - - - ko:K01118 - - - - ko00000,ko01000 - - - Flavodoxin_2 k141_19101_3 1042377.AFPJ01000020_gene2086 1.45e-155 442.0 COG0668@1|root,COG0668@2|Bacteria,1PMY3@1224|Proteobacteria,1SZY7@1236|Gammaproteobacteria,4672N@72275|Alteromonadaceae 1236|Gammaproteobacteria M Mechanosensitive ion channel - - - - - - - - - - - - MS_channel k141_19101_4 118166.JH976537_gene77 9.49e-151 434.0 COG2066@1|root,COG2066@2|Bacteria,1G1IK@1117|Cyanobacteria,1H7V2@1150|Oscillatoriales 1117|Cyanobacteria E Belongs to the glutaminase family - - 3.5.1.2 ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 - R00256,R01579 RC00010,RC02798 ko00000,ko00001,ko01000 - - - Glutaminase k141_19101_5 1453501.JELR01000002_gene752 0.0 951.0 COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,1RR00@1236|Gammaproteobacteria,4653D@72275|Alteromonadaceae 1236|Gammaproteobacteria EH Belongs to the TPP enzyme family budB - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N k141_19101_6 1279017.AQYJ01000029_gene3967 3.76e-306 839.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,464PE@72275|Alteromonadaceae 1236|Gammaproteobacteria C Belongs to the aldehyde dehydrogenase family - - 1.2.1.3,1.2.1.71 ko:K00128,ko:K06447 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05049,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_19101_8 1071679.BG57_11195 2.38e-190 534.0 COG0604@1|root,COG0604@2|Bacteria,1MXUX@1224|Proteobacteria,2VHPT@28216|Betaproteobacteria,1K07F@119060|Burkholderiaceae 28216|Betaproteobacteria C alcohol dehydrogenase - - - - - - - - - - - - ADH_N,ADH_zinc_N k141_8453_1 1453501.JELR01000001_gene2497 0.0 1241.0 COG2902@1|root,COG2902@2|Bacteria,1MXNV@1224|Proteobacteria,1RQVZ@1236|Gammaproteobacteria,464UW@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG2902 NAD-specific glutamate dehydrogenase gdhB - 1.4.1.2 ko:K15371 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 - R00243 RC00006,RC02799 ko00000,ko00001,ko01000 - - - Bac_GDH,GDH_N k141_22692_1 1294265.JCM21738_46 1.09e-93 275.0 COG0700@1|root,COG0700@2|Bacteria,1V45M@1239|Firmicutes,4HH1Y@91061|Bacilli,1ZFIY@1386|Bacillus 91061|Bacilli S Spore maturation protein spmB - - ko:K06374 - - - - ko00000 - - - Gate k141_27402_1 67373.JOBF01000007_gene2328 0.000153 49.3 COG0531@1|root,COG0531@2|Bacteria,2GMXA@201174|Actinobacteria 201174|Actinobacteria E amino acid - - - - - - - - - - - - AA_permease_2 k141_28653_1 218284.CCDN010000007_gene3797 2.53e-258 719.0 COG0445@1|root,COG0445@2|Bacteria,1TQ4B@1239|Firmicutes,4HA6S@91061|Bacilli,1ZB67@1386|Bacillus 91061|Bacilli D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 gidA GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - ko:K03495 - - R08701 RC00053,RC00209,RC00870 ko00000,ko03016,ko03036 - - - GIDA,GIDA_assoc k141_3677_1 218284.CCDN010000001_gene1175 3.45e-114 333.0 COG0258@1|root,COG0258@2|Bacteria,1TQ05@1239|Firmicutes,4H9UW@91061|Bacilli,1ZB2Z@1386|Bacillus 91061|Bacilli L 5'3' exonuclease ypcP - - - - - - - - - - - 5_3_exonuc,5_3_exonuc_N k141_21525_2 218284.CCDN010000005_gene3371 3.08e-144 417.0 COG4857@1|root,COG4857@2|Bacteria,1TPHY@1239|Firmicutes,4H9QU@91061|Bacilli,1ZBZS@1386|Bacillus 91061|Bacilli F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate mtnK GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.100 ko:K00899 ko00270,ko01100,map00270,map01100 M00034 R04143 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - APH k141_14377_1 1117379.BABA_21041 7.09e-21 83.6 29SA4@1|root,30DEM@2|Bacteria,1UB7I@1239|Firmicutes,4IMK9@91061|Bacilli,1ZKBZ@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_13206_1 218284.CCDN010000005_gene3432 2.58e-102 301.0 COG0614@1|root,COG0614@2|Bacteria,1TQV7@1239|Firmicutes,4HCF3@91061|Bacilli,1ZBF0@1386|Bacillus 91061|Bacilli P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component btuF - - ko:K02016 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - iYO844.BSU33180 Peripla_BP_2 k141_4865_1 223926.28807891 1.28e-83 263.0 COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,1RPF7@1236|Gammaproteobacteria,1XTUK@135623|Vibrionales 135623|Vibrionales CO Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps dsbD GO:0003674,GO:0003756,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008152,GO:0009987,GO:0015035,GO:0015036,GO:0016020,GO:0016021,GO:0016043,GO:0016491,GO:0016667,GO:0016853,GO:0016860,GO:0016864,GO:0017004,GO:0019725,GO:0022607,GO:0031224,GO:0031226,GO:0034622,GO:0042592,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0055114,GO:0065003,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0140096 1.8.1.8 ko:K04084 - - - - ko00000,ko01000,ko03110 5.A.1.1 - - DsbC,DsbD,Thioredoxin_7 k141_16716_1 218284.CCDN010000007_gene3819 1.33e-46 158.0 COG1226@1|root,COG1226@2|Bacteria,1TT0B@1239|Firmicutes,4HBDX@91061|Bacilli,1ZDQI@1386|Bacillus 91061|Bacilli P Ion channel kch - - ko:K10716 - - - - ko00000,ko02000 1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6 - - Ion_trans_2,TrkA_N k141_20271_2 1033734.CAET01000025_gene1084 1.98e-18 80.1 2EH08@1|root,33ASA@2|Bacteria,1VKFJ@1239|Firmicutes,4HRDY@91061|Bacilli,1ZK21@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_9596_1 218284.CCDN010000006_gene3746 1.24e-146 444.0 COG3459@1|root,COG3459@2|Bacteria,1TVMK@1239|Firmicutes,4H9ZP@91061|Bacilli,1ZF4F@1386|Bacillus 91061|Bacilli G Glycosyl hydrolase 36 superfamily, catalytic domain chvB1 - 2.4.1.20,2.4.1.333 ko:K00702,ko:K13688,ko:K21298 ko00500,ko01100,map00500,map01100 - R00952 RC00049 ko00000,ko00001,ko01000,ko01003 - GH94,GT36,GT84 - Glyco_hydro_36,Glyco_transf_36 k141_123_2 1279017.AQYJ01000027_gene1714 0.0 995.0 COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,1SZQQ@1236|Gammaproteobacteria,46CZH@72275|Alteromonadaceae 1236|Gammaproteobacteria S Putative modulator of DNA gyrase - - - ko:K03568 - - - - ko00000,ko01002 - - - PmbA_TldD k141_13207_1 1123368.AUIS01000008_gene2160 3e-110 336.0 COG1328@1|root,COG1328@2|Bacteria,1MWMS@1224|Proteobacteria,1RNHS@1236|Gammaproteobacteria,2NCRR@225057|Acidithiobacillales 225057|Acidithiobacillales F ribonucleoside-triphosphate reductase - - 1.1.98.6 ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R11633,R11634,R11635,R11636 RC00613 ko00000,ko00001,ko00002,ko01000 - - - ATP-cone,NRDD k141_15573_1 886293.Sinac_1691 4.7e-51 181.0 COG3379@1|root,COG3379@2|Bacteria,2IXA8@203682|Planctomycetes 203682|Planctomycetes S Type I phosphodiesterase / nucleotide pyrophosphatase - - - - - - - - - - - - Phosphodiest k141_17964_1 1453501.JELR01000001_gene1925 3.01e-74 242.0 COG1506@1|root,COG1506@2|Bacteria,1MUJ3@1224|Proteobacteria,1RPAW@1236|Gammaproteobacteria,464D0@72275|Alteromonadaceae 1236|Gammaproteobacteria E X-Pro dipeptidyl-peptidase (S15 family) - - - - - - - - - - - - Peptidase_S9 k141_25033_1 218284.CCDN010000001_gene165 1.19e-152 444.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,1ZASV@1386|Bacillus 91061|Bacilli V COG1132 ABC-type multidrug transport system, ATPase and permease components yknU GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702 - ko:K06147,ko:K11085 ko02010,map02010 - - - ko00000,ko00001,ko01000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran k141_124_1 1382358.JHVN01000013_gene1812 6.02e-110 323.0 COG3483@1|root,COG3483@2|Bacteria,1TR14@1239|Firmicutes,4H9X1@91061|Bacilli 91061|Bacilli E Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety kynA GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019752,GO:0020037,GO:0022607,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.11 ko:K00453 ko00380,ko01100,map00380,map01100 M00038 R00678 RC00356 ko00000,ko00001,ko00002,ko01000 - - - Trp_dioxygenase k141_7210_3 1280001.BAOA01000051_gene1466 3.89e-33 114.0 COG0267@1|root,COG0267@2|Bacteria,1N6QV@1224|Proteobacteria,1SCEJ@1236|Gammaproteobacteria,1XYW1@135623|Vibrionales 135623|Vibrionales J Belongs to the bacterial ribosomal protein bL33 family rpmG GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02913 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L33 k141_7210_4 223926.28805170 2.85e-89 264.0 2EG7K@1|root,339ZF@2|Bacteria,1NHRB@1224|Proteobacteria,1SIIJ@1236|Gammaproteobacteria,1XX2H@135623|Vibrionales 135623|Vibrionales - - VV10822 - - - - - - - - - - - - k141_7210_5 1116375.VEJY3_00885 4.15e-189 525.0 COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,1RP3J@1236|Gammaproteobacteria,1XSAC@135623|Vibrionales 135623|Vibrionales L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates fpg GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.2.2.23,4.2.99.18 ko:K10563 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Fapy_DNA_glyco,H2TH,zf-FPG_IleRS k141_7210_6 1187848.AJYQ01000004_gene143 2.29e-119 348.0 COG3306@1|root,COG3306@2|Bacteria,1R7HN@1224|Proteobacteria,1SAQK@1236|Gammaproteobacteria,1XX32@135623|Vibrionales 135623|Vibrionales M Glycosyltransferase family 25 (LPS biosynthesis protein) - - - ko:K07270 - - - - ko00000 - GT25 - Glyco_transf_25 k141_7210_7 675816.VIA_000538 1.37e-126 372.0 COG0438@1|root,COG0438@2|Bacteria,1MWSZ@1224|Proteobacteria,1RMQP@1236|Gammaproteobacteria,1XWTF@135623|Vibrionales 135623|Vibrionales M Glycosyl transferases group 1 - - - - - - - - - - - - Glycos_transf_1 k141_7210_8 243277.VC_0222 9.61e-86 255.0 COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,1S41J@1236|Gammaproteobacteria,1XUJI@135623|Vibrionales 135623|Vibrionales H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate coaD GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 ko:K00954 ko00770,ko01100,map00770,map01100 M00120 R03035 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like k141_7210_9 575788.VS_0187 5.39e-134 389.0 2DB9N@1|root,2Z7XI@2|Bacteria,1PSDD@1224|Proteobacteria,1S2TM@1236|Gammaproteobacteria,1XW5I@135623|Vibrionales 135623|Vibrionales S Glycosyl transferase family 90 - - - - - - - - - - - - Glyco_transf_90 k141_7210_10 1191299.AJYX01000038_gene3422 1.84e-192 541.0 COG0859@1|root,COG0859@2|Bacteria,1MYZA@1224|Proteobacteria,1RR6K@1236|Gammaproteobacteria,1XSR4@135623|Vibrionales 135623|Vibrionales M COG0859 ADP-heptose LPS heptosyltransferase - - - ko:K12982 - - - - ko00000,ko01000,ko01003,ko01005 - GT9 - Glyco_transf_9 k141_7210_11 945543.VIBR0546_16341 2.86e-109 320.0 COG1718@1|root,COG1718@2|Bacteria,1QV96@1224|Proteobacteria,1T2AM@1236|Gammaproteobacteria,1Y343@135623|Vibrionales 135623|Vibrionales H Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position kdkA - 2.7.1.166 ko:K11211 ko00540,map00540 - R09767 RC00002,RC00078 ko00000,ko00001,ko01000 - - - Kdo k141_7210_12 1219065.VPR01S_04_02120 7.26e-67 210.0 COG0515@1|root,COG0515@2|Bacteria,1RI1C@1224|Proteobacteria,1RNN5@1236|Gammaproteobacteria,1Y13U@135623|Vibrionales 135623|Vibrionales KLT PhoP regulatory network protein YrbL - - - - - - - - - - - - YrbL-PhoP_reg k141_7210_13 1116375.VEJY3_00910 1.34e-128 380.0 COG0438@1|root,COG0438@2|Bacteria,1NE3V@1224|Proteobacteria,1RQE3@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Catalyzes the addition of the first glucose residue to the LPS core - - - ko:K02844 ko00540,ko01100,map00540,map01100 M00080 - - ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT4 - Glyco_transf_4,Glycos_transf_1 k141_28655_2 946235.CAER01000008_gene449 2.33e-13 69.7 COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,4H9SZ@91061|Bacilli,23IK8@182709|Oceanobacillus 91061|Bacilli E Sodium:alanine symporter family glnT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03310,ko:K11626 ko02020,map02020 - - - ko00000,ko00001 2.A.25 - - Na_Ala_symp k141_19104_1 218284.CCDN010000006_gene3536 5.82e-105 315.0 COG1785@1|root,COG1785@2|Bacteria,1TQCI@1239|Firmicutes,4HA27@91061|Bacilli,1ZB3J@1386|Bacillus 91061|Bacilli P Belongs to the alkaline phosphatase family phoB - 3.1.3.1 ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 M00126 R02135,R04620 RC00017 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 - - - Alk_phosphatase k141_16718_1 42565.FP66_14590 2.07e-107 312.0 COG3672@1|root,COG3672@2|Bacteria,1RDQS@1224|Proteobacteria,1S3Y1@1236|Gammaproteobacteria,1XJ4Z@135619|Oceanospirillales 135619|Oceanospirillales S Bacterial transglutaminase-like cysteine proteinase BTLCP - - - - - - - - - - - - Peptidase_C93 k141_22693_1 1453501.JELR01000001_gene1863 1.67e-13 70.9 COG3134@1|root,COG3134@2|Bacteria,1MVWD@1224|Proteobacteria,1RQR9@1236|Gammaproteobacteria,468W9@72275|Alteromonadaceae 1236|Gammaproteobacteria S Glycine zipper 2TM domain - - - - - - - - - - - - Rick_17kDa_Anti k141_22910_2 1279017.AQYJ01000027_gene1772 3.26e-214 603.0 COG0144@1|root,COG0144@2|Bacteria,1MWPE@1224|Proteobacteria,1RN8X@1236|Gammaproteobacteria,465KP@72275|Alteromonadaceae 1236|Gammaproteobacteria J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA sun GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 ko:K03500 - - - - ko00000,ko01000,ko03009 - - - Methyltr_RsmB-F,Methyltr_RsmF_N,NusB k141_19294_2 218284.CCDN010000001_gene743 2.88e-151 435.0 COG1030@1|root,COG1030@2|Bacteria,1TR54@1239|Firmicutes,4H9P9@91061|Bacilli,1ZCTF@1386|Bacillus 91061|Bacilli O COG1030 Membrane-bound serine protease (ClpP class) yqeZ - - ko:K07403 - - - - ko00000 - - - NfeD,SDH_sah k141_3910_1 1116375.VEJY3_22471 1.02e-174 491.0 COG2354@1|root,COG2354@2|Bacteria,1MVYU@1224|Proteobacteria,1RMUZ@1236|Gammaproteobacteria,1XTCV@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria yedI - - ko:K09781 - - - - ko00000 - - - DUF808 k141_3910_2 1116375.VEJY3_22466 1.48e-246 677.0 COG0418@1|root,COG0418@2|Bacteria,1MUYP@1224|Proteobacteria,1RNEN@1236|Gammaproteobacteria,1XSNV@135623|Vibrionales 135623|Vibrionales F Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate pyrC GO:0003674,GO:0003824,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 k141_3910_4 223926.28808577 1.7e-47 166.0 COG1018@1|root,COG3217@1|root,COG1018@2|Bacteria,COG3217@2|Bacteria,1MXN2@1224|Proteobacteria,1RMN7@1236|Gammaproteobacteria,1XSP5@135623|Vibrionales 135623|Vibrionales C Fe-S protein VVA0408 - - ko:K07140 - - - - ko00000 - - - FAD_binding_6,Fer2,MOSC,MOSC_N,NAD_binding_1 k141_35902_1 1265505.ATUG01000002_gene2120 9.18e-48 182.0 COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,42N78@68525|delta/epsilon subdivisions,2WM0M@28221|Deltaproteobacteria,2MHVS@213118|Desulfobacterales 28221|Deltaproteobacteria M Mechanosensitive ion channel mscS-2 - - - - - - - - - - - MS_channel k141_8621_1 1408813.AYMG01000012_gene980 1.26e-11 70.5 COG3712@1|root,COG3712@2|Bacteria,4NISZ@976|Bacteroidetes,1IWEA@117747|Sphingobacteriia 976|Bacteroidetes PT Domain of unknown function (DUF4974) - - - - - - - - - - - - DUF4974,FecR k141_8621_2 1209072.ALBT01000038_gene2299 1.23e-31 117.0 COG1595@1|root,COG1595@2|Bacteria,1PHP5@1224|Proteobacteria,1RU9B@1236|Gammaproteobacteria,1FII9@10|Cellvibrio 1236|Gammaproteobacteria K ECF sigma factor - - - - - - - - - - - - Sigma70_r2,Sigma70_r4_2 k141_32297_1 218284.CCDN010000008_gene4168 1.04e-20 82.8 2EFZF@1|root,339RM@2|Bacteria,1VMG6@1239|Firmicutes,4HR8G@91061|Bacilli,1ZK3J@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_20430_1 946235.CAER01000063_gene2350 7.46e-115 343.0 COG0477@1|root,COG2814@2|Bacteria,1TPRN@1239|Firmicutes,4H9VV@91061|Bacilli,23MFK@182709|Oceanobacillus 91061|Bacilli EGP Major Facilitator Superfamily - - - ko:K18926 - M00715 - - ko00000,ko00002,ko02000 2.A.1.3.30 - - MFS_1 k141_28875_2 1485544.JQKP01000011_gene748 1.1e-33 128.0 COG2270@1|root,COG2270@2|Bacteria,1QUVA@1224|Proteobacteria,2WHTQ@28216|Betaproteobacteria 28216|Betaproteobacteria S AmpG muropeptide MFS transporter K08218 - - - ko:K08218 ko01501,map01501 M00628 - - ko00000,ko00001,ko00002,ko02000 2.A.1.25 - - MFS_1 k141_15762_1 2340.JV46_17790 5.77e-23 96.3 COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,1RPM1@1236|Gammaproteobacteria,1J53E@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family hprA - 1.1.1.29 ko:K00018 ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200 M00346 R00717,R01388 RC00031,RC00042 ko00000,ko00001,ko00002,ko01000 - - - 2-Hacid_dh,2-Hacid_dh_C k141_12264_1 1453501.JELR01000002_gene924 5.24e-51 171.0 COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,1RM8Z@1236|Gammaproteobacteria,465JS@72275|Alteromonadaceae 1236|Gammaproteobacteria O HflC and HflK could regulate a protease hflC GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009408,GO:0009628,GO:0009897,GO:0009986,GO:0016020,GO:0016021,GO:0016787,GO:0019538,GO:0031224,GO:0031226,GO:0031233,GO:0032991,GO:0043086,GO:0043170,GO:0044092,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0050790,GO:0050896,GO:0065007,GO:0065009,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0098796,GO:0140096,GO:1901564 - ko:K04087 - M00742 - - ko00000,ko00002,ko01000 - - - Band_7 k141_29935_1 1294265.JCM21738_2082 2.47e-123 355.0 COG1459@1|root,COG1459@2|Bacteria,1U00C@1239|Firmicutes,4HGUA@91061|Bacilli,1ZCQK@1386|Bacillus 91061|Bacilli NU COG1459 Type II secretory pathway, component PulF comGB - - ko:K02244 - M00429 - - ko00000,ko00002,ko02044 3.A.14.1 - - T2SSF k141_6354_2 997296.PB1_00825 1.18e-28 113.0 COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,4HAAP@91061|Bacilli,1ZB4E@1386|Bacillus 91061|Bacilli S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay rnjB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 - ko:K12574 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - Lactamase_B,RMMBL k141_26604_1 1279017.AQYJ01000028_gene2315 1.06e-10 59.3 COG0517@1|root,COG0517@2|Bacteria,1NAGC@1224|Proteobacteria,1SF8G@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain in cystathionine beta-synthase and other proteins. - - - ko:K04767 - - - - ko00000 - - - CBS k141_22911_1 1453501.JELR01000002_gene759 1.52e-169 484.0 COG1012@1|root,COG1012@2|Bacteria,1MUHV@1224|Proteobacteria,1RNFN@1236|Gammaproteobacteria,465NX@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1012 NAD-dependent aldehyde dehydrogenases mmsA - 1.2.1.18,1.2.1.27 ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 M00013 R00705,R00706,R00922,R00935 RC00004,RC02723,RC02817 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_9774_2 1123228.AUIH01000046_gene1835 2.52e-56 177.0 2AMAC@1|root,31C5B@2|Bacteria,1RI20@1224|Proteobacteria,1S5XV@1236|Gammaproteobacteria,1XR85@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_18189_1 218284.CCDN010000011_gene4425 3.18e-118 350.0 COG2252@1|root,COG2252@2|Bacteria,1TQC6@1239|Firmicutes,4HANG@91061|Bacilli,1ZARH@1386|Bacillus 91061|Bacilli S permease pbuG - - ko:K06901 - - - - ko00000,ko02000 2.A.1.40 - iYO844.BSU06370 Xan_ur_permease k141_19295_1 1453501.JELR01000001_gene2156 6.18e-57 197.0 COG1026@1|root,COG1026@2|Bacteria,1MVDJ@1224|Proteobacteria,1RYNI@1236|Gammaproteobacteria,465V1@72275|Alteromonadaceae 1236|Gammaproteobacteria S Zn-dependent peptidases, insulinase-like - - - ko:K06972 - - - - ko00000,ko01000,ko01002 - - - M16C_assoc,Peptidase_M16,Peptidase_M16_C k141_24038_1 1347086.CCBA010000030_gene237 4.42e-101 315.0 COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,4HA3G@91061|Bacilli,1ZAVY@1386|Bacillus 91061|Bacilli T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,PAS_4,PAS_9 k141_13410_2 1042377.AFPJ01000020_gene2060 2.16e-169 481.0 COG0560@1|root,COG0560@2|Bacteria,1MW38@1224|Proteobacteria,1RQAT@1236|Gammaproteobacteria,464CR@72275|Alteromonadaceae 1236|Gammaproteobacteria E haloacid dehalogenase-like hydrolase - - - - - - - - - - - - HAD k141_13410_3 1042377.AFPJ01000020_gene2061 0.0 923.0 COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,1RN2V@1236|Gammaproteobacteria,465NQ@72275|Alteromonadaceae 1236|Gammaproteobacteria P Sulfatase - - 3.1.6.1 ko:K01130 ko00140,ko00600,map00140,map00600 - R03980,R04856 RC00128,RC00231 ko00000,ko00001,ko01000 - - - Sulfatase,Sulfatase_C k141_13410_4 234267.Acid_4083 3.36e-302 836.0 COG3119@1|root,COG3119@2|Bacteria,3Y733@57723|Acidobacteria 57723|Acidobacteria P Sulfatase - - - - - - - - - - - - Sulfatase k141_13410_5 521674.Plim_1647 0.0 920.0 COG3119@1|root,COG3119@2|Bacteria,2J2YF@203682|Planctomycetes 203682|Planctomycetes P Sulfatase - - 3.1.6.1 ko:K01130 ko00140,ko00600,map00140,map00600 - R03980,R04856 RC00128,RC00231 ko00000,ko00001,ko01000 - - - Sulfatase,Sulfatase_C k141_22912_1 333138.LQ50_19655 6.85e-71 219.0 COG1670@1|root,COG1670@2|Bacteria,1V4T4@1239|Firmicutes,4HGGP@91061|Bacilli,1ZGQ5@1386|Bacillus 91061|Bacilli J Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_3 k141_28876_1 218284.CCDN010000002_gene2255 1.57e-97 301.0 COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,4H9SP@91061|Bacilli,1ZAPS@1386|Bacillus 91061|Bacilli P COG2217 Cation transport ATPase zosA - 3.6.3.3,3.6.3.5 ko:K01534 - - - - ko00000,ko01000 3.A.3.6 - - E1-E2_ATPase,Hydrolase k141_16974_1 218284.CCDN010000002_gene2869 7.18e-20 88.6 COG1173@1|root,COG1173@2|Bacteria,1V21B@1239|Firmicutes,4HJ5Y@91061|Bacilli,1ZFPK@1386|Bacillus 91061|Bacilli EP ABC transporter (permease) - - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 k141_16974_2 218284.CCDN010000002_gene2751 1.26e-76 237.0 COG0601@1|root,COG0601@2|Bacteria,1UYTT@1239|Firmicutes,4IEZM@91061|Bacilli,1ZJ9K@1386|Bacillus 91061|Bacilli EP Binding-protein-dependent transport system inner membrane component - - - - - - - - - - - - BPD_transp_1 k141_20431_1 10756.CAPSD_BPPH2 1.09e-139 407.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QNI0@10744|Podoviridae 10744|Podoviridae S viral capsid - GO:0005575,GO:0019012,GO:0019028,GO:0019030,GO:0039617,GO:0044423,GO:0046729 - - - - - - - - - - - k141_33553_1 1279017.AQYJ01000028_gene2046 5.75e-31 115.0 2DQKY@1|root,337IG@2|Bacteria,1NCYH@1224|Proteobacteria,1SCMR@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF4124) - - - - - - - - - - - - DUF4124 k141_33553_2 1453501.JELR01000002_gene1304 3.45e-172 484.0 COG1281@1|root,COG1281@2|Bacteria,1MUMU@1224|Proteobacteria,1RMP3@1236|Gammaproteobacteria,466I9@72275|Alteromonadaceae 1236|Gammaproteobacteria O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress hslO GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0006979,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0031647,GO:0036506,GO:0042026,GO:0042802,GO:0043167,GO:0043169,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0065007,GO:0065008 - ko:K04083 - - - - ko00000,ko03110 - - - HSP33 k141_33553_3 1279017.AQYJ01000028_gene2044 0.0 942.0 COG1866@1|root,COG1866@2|Bacteria,1MWXN@1224|Proteobacteria,1RPM0@1236|Gammaproteobacteria,464KD@72275|Alteromonadaceae 1236|Gammaproteobacteria H Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA pckA GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 4.1.1.49 ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 M00003,M00170 R00341 RC00002,RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPCK_ATP k141_26606_1 377629.TERTU_2066 5.7e-68 226.0 COG4631@1|root,COG4631@2|Bacteria,1NQSR@1224|Proteobacteria,1T1HI@1236|Gammaproteobacteria,2PPB9@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain xdhB - 1.17.1.4 ko:K13482 ko00230,ko01100,ko01120,map00230,map01100,map01120 M00546 R01768,R02103 RC00143 ko00000,ko00001,ko00002,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 k141_5026_1 1279017.AQYJ01000025_gene756 0.0 1430.0 COG2902@1|root,COG2902@2|Bacteria,1MXNV@1224|Proteobacteria,1RQVZ@1236|Gammaproteobacteria,464UW@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG2902 NAD-specific glutamate dehydrogenase gdhB - 1.4.1.2 ko:K15371 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 - R00243 RC00006,RC02799 ko00000,ko00001,ko01000 - - - Bac_GDH,GDH_N k141_31233_1 42565.FP66_00695 3.25e-94 279.0 2DUJ9@1|root,33QY4@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k141_19312_1 1121937.AUHJ01000020_gene1276 5.4e-231 650.0 COG0477@1|root,COG2814@2|Bacteria,1MU1I@1224|Proteobacteria,1RNTG@1236|Gammaproteobacteria,4672P@72275|Alteromonadaceae 1236|Gammaproteobacteria U Major facilitator superfamily emrB - - ko:K03446 - M00701 - - ko00000,ko00002,ko02000 2.A.1.3 - - MFS_1 k141_19312_2 1279017.AQYJ01000028_gene2330 7.64e-163 467.0 COG1566@1|root,COG1566@2|Bacteria,1MU7I@1224|Proteobacteria,1RMAD@1236|Gammaproteobacteria,466Y4@72275|Alteromonadaceae 1236|Gammaproteobacteria V HlyD membrane-fusion protein of T1SS emrA - - ko:K03543 - M00701 - - ko00000,ko00002,ko02000 8.A.1.1 - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 k141_19312_3 1297865.APJD01000035_gene5493 3.83e-23 96.7 COG1846@1|root,COG1846@2|Bacteria,1MZY5@1224|Proteobacteria,2U9EE@28211|Alphaproteobacteria,3JSF5@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria K MarR family MA20_23255 - - ko:K06075 - - - - ko00000,ko03000 - - - MarR,MarR_2 k141_19312_4 1298593.TOL_1201 4.43e-94 278.0 COG0590@1|root,COG0590@2|Bacteria,1RE8P@1224|Proteobacteria,1S3V3@1236|Gammaproteobacteria,1XJK0@135619|Oceanospirillales 135619|Oceanospirillales FJ MafB19-like deaminase - - 3.5.4.1 ko:K01485 ko00240,ko00330,ko01100,map00240,map00330,map01100 - R00974,R01411,R02922 RC00074,RC00514,RC00809 ko00000,ko00001,ko01000 - - - dCMP_cyt_deam_1 k141_19312_5 1541065.JRFE01000057_gene6278 1.11e-09 59.3 COG0530@1|root,COG0530@2|Bacteria,1G7C1@1117|Cyanobacteria 1117|Cyanobacteria P Sodium/calcium exchanger protein - - - - - - - - - - - - Na_Ca_ex k141_5059_1 218284.CCDN010000005_gene3187 3.67e-21 89.7 COG4758@1|root,COG4758@2|Bacteria,1TSDR@1239|Firmicutes,4HCRP@91061|Bacilli,1ZE5M@1386|Bacillus 91061|Bacilli S Cell wall-active antibiotics response 4TMS YvqF - - - ko:K11622 ko02020,map02020 - - - ko00000,ko00001 - - - DUF2154 k141_5059_2 218284.CCDN010000005_gene3188 1.04e-119 352.0 COG4585@1|root,COG4585@2|Bacteria,1TPDG@1239|Firmicutes,4HC7E@91061|Bacilli,1ZB48@1386|Bacillus 91061|Bacilli T Histidine kinase - - 2.7.13.3 ko:K11617 ko02020,map02020 M00481,M00754 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA_3 k141_9803_1 218284.CCDN010000005_gene3224 2.13e-85 261.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,1ZB7V@1386|Bacillus 91061|Bacilli I Belongs to the thiolase family thlA - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N k141_13447_1 1279017.AQYJ01000021_gene2808 2.49e-49 167.0 COG2959@1|root,COG2959@2|Bacteria,1N3SM@1224|Proteobacteria,1S9N7@1236|Gammaproteobacteria,46870@72275|Alteromonadaceae 1236|Gammaproteobacteria H enzyme of heme biosynthesis - - - - - - - - - - - - - k141_10991_1 218284.CCDN010000001_gene1393 1.63e-98 298.0 COG2309@1|root,COG2309@2|Bacteria,1TP65@1239|Firmicutes,4H9W8@91061|Bacilli,1ZCU3@1386|Bacillus 91061|Bacilli E COG2309 Leucyl aminopeptidase (aminopeptidase T) - - - ko:K19689 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M29 k141_21726_1 1461580.CCAS010000002_gene267 3.24e-99 299.0 COG1379@1|root,COG1379@2|Bacteria,1TP9P@1239|Firmicutes,4HCQ4@91061|Bacilli,1ZASI@1386|Bacillus 91061|Bacilli L DNA helicase yqxK - - - - - - - - - - - PHP_C k141_18212_1 1095769.CAHF01000005_gene1634 2.57e-54 192.0 COG0506@1|root,COG4230@1|root,COG0506@2|Bacteria,COG4230@2|Bacteria,1MV93@1224|Proteobacteria,2VITK@28216|Betaproteobacteria,472KA@75682|Oxalobacteraceae 28216|Betaproteobacteria CE Oxidizes proline to glutamate for use as a carbon and nitrogen source putA - 1.2.1.88,1.3.8.7,1.5.5.2 ko:K00249,ko:K00294,ko:K13821 ko00071,ko00250,ko00280,ko00330,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00250,map00280,map00330,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00245,R00707,R00708,R00924,R01175,R01253,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04444,R04445,R04751,R04754,R05051 RC00052,RC00068,RC00076,RC00080,RC00083,RC00095,RC00148,RC00216,RC00242,RC00246,RC00255 ko00000,ko00001,ko00002,ko01000,ko03000 - - - Aldedh,Pro_dh,Pro_dh-DNA_bdg k141_25291_1 218284.CCDN010000002_gene2132 1.08e-165 477.0 COG1574@1|root,COG1574@2|Bacteria,1TQ6G@1239|Firmicutes,4H9T6@91061|Bacilli,1ZC1J@1386|Bacillus 91061|Bacilli S Amidohydrolase family ytcJ - - - - - - - - - - - Amidohydro_3 k141_35927_1 1499967.BAYZ01000026_gene1617 6.33e-79 267.0 COG0178@1|root,COG0178@2|Bacteria,2NQR8@2323|unclassified Bacteria 2|Bacteria L ABC transporter uvrA2 - - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran k141_31248_1 218284.CCDN010000001_gene57 2.35e-51 169.0 COG0543@1|root,COG0543@2|Bacteria,1TQ5D@1239|Firmicutes,4HAU4@91061|Bacilli,1ZBJI@1386|Bacillus 91061|Bacilli C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) pyrK GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042602,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0052875,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - ko:K02823 ko00240,ko01100,map00240,map01100 - - - ko00000,ko00001 - - iYO844.BSU15530 DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1 k141_26637_1 589873.EP13_17890 3.19e-14 81.6 COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,1S13F@1236|Gammaproteobacteria,466IW@72275|Alteromonadaceae 1236|Gammaproteobacteria S Sulfotransferase domain - - - - - - - - - - - - Sulfotransfer_3,TPR_16,TPR_19,TPR_8 k141_26637_2 1453501.JELR01000002_gene773 0.0 1339.0 COG1629@1|root,COG4771@2|Bacteria,1MVFB@1224|Proteobacteria,1RNMS@1236|Gammaproteobacteria,469SJ@72275|Alteromonadaceae 1236|Gammaproteobacteria P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec k141_34776_1 1279017.AQYJ01000028_gene2420 4.89e-96 285.0 COG3038@1|root,COG3038@2|Bacteria,1MZ7X@1224|Proteobacteria,1S3RF@1236|Gammaproteobacteria,467A7@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG3038 Cytochrome B561 yceJ GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K12262 - - - - ko00000 - - - Ni_hydr_CYTB k141_19313_1 1453501.JELR01000001_gene2280 1.03e-82 258.0 COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,1RMSE@1236|Gammaproteobacteria,464G9@72275|Alteromonadaceae 1236|Gammaproteobacteria EH COG0147 Anthranilate para-aminobenzoate synthases component I pabB GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.6.1.85 ko:K01665 ko00790,map00790 - R01716 RC00010,RC01418 ko00000,ko00001,ko01000 - - iEC042_1314.EC042_1977 Anth_synt_I_N,Chorismate_bind k141_6376_2 945543.VIBR0546_02414 9.47e-243 669.0 COG1902@1|root,COG1902@2|Bacteria,1MVIX@1224|Proteobacteria,1RMFI@1236|Gammaproteobacteria,1XSZS@135623|Vibrionales 135623|Vibrionales C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family - - - ko:K10680 ko00633,ko01120,map00633,map01120 - R08014,R08017,R08042 RC00250 ko00000,ko00001,ko01000 - - - Oxidored_FMN k141_32325_1 240302.BN982_03637 3.74e-128 389.0 COG2866@1|root,COG2866@2|Bacteria,1TSF6@1239|Firmicutes,4HDT5@91061|Bacilli 91061|Bacilli E Carboxypeptidase - - - - - - - - - - - - Peptidase_M14 k141_27571_2 1453501.JELR01000002_gene924 6.23e-154 438.0 COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,1RM8Z@1236|Gammaproteobacteria,465JS@72275|Alteromonadaceae 1236|Gammaproteobacteria O HflC and HflK could regulate a protease hflC GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009408,GO:0009628,GO:0009897,GO:0009986,GO:0016020,GO:0016021,GO:0016787,GO:0019538,GO:0031224,GO:0031226,GO:0031233,GO:0032991,GO:0043086,GO:0043170,GO:0044092,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0050790,GO:0050896,GO:0065007,GO:0065009,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0098796,GO:0140096,GO:1901564 - ko:K04087 - M00742 - - ko00000,ko00002,ko01000 - - - Band_7 k141_412_1 1294265.JCM21738_3818 6.39e-54 180.0 COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,4HAE3@91061|Bacilli,1ZDU5@1386|Bacillus 91061|Bacilli E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component braC - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 k141_18213_1 545693.BMQ_0878 1.9e-29 117.0 COG0266@1|root,COG0266@2|Bacteria,1TP6F@1239|Firmicutes,4HBIU@91061|Bacilli,1ZCVD@1386|Bacillus 91061|Bacilli L Formamidopyrimidine-DNA glycosylase H2TH domain - - 4.2.99.18 ko:K05522 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Fapy_DNA_glyco,H2TH,zf-FPG_IleRS k141_9806_1 1294265.JCM21738_4651 4.75e-118 338.0 COG2259@1|root,COG2259@2|Bacteria,1V4ER@1239|Firmicutes,4HGZN@91061|Bacilli,1ZG3Q@1386|Bacillus 91061|Bacilli S DoxX - - 1.8.5.2 ko:K16937 ko00920,ko01120,map00920,map01120 - R07177 - ko00000,ko00001,ko01000 3.D.4.9 - - DoxX k141_12296_1 675814.VIC_001636 2.78e-160 460.0 COG0381@1|root,COG0381@2|Bacteria,1MWZN@1224|Proteobacteria,1RPNC@1236|Gammaproteobacteria,1XUPD@135623|Vibrionales 135623|Vibrionales G Belongs to the UDP-N-acetylglucosamine 2-epimerase family - - 5.1.3.14 ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 M00362 R00420 RC00290 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Epimerase_2 k141_6377_1 1294265.JCM21738_4433 2.46e-70 213.0 2D1ET@1|root,32TAJ@2|Bacteria,1V8Q4@1239|Firmicutes,4HQUW@91061|Bacilli,1ZI5D@1386|Bacillus 91061|Bacilli S Cell division protein FtsJ - - - - - - - - - - - - - k141_32326_2 218284.CCDN010000007_gene3919 4.05e-105 306.0 COG1595@1|root,COG1595@2|Bacteria,1UIX6@1239|Firmicutes,4ISVD@91061|Bacilli,1ZS74@1386|Bacillus 91061|Bacilli K Sigma-70, region 4 - - - - - - - - - - - - Sigma70_r4,Sigma70_r4_2 k141_34777_2 218284.CCDN010000007_gene3906 1.48e-25 102.0 COG0451@1|root,COG0451@2|Bacteria,1TSUN@1239|Firmicutes,4HA3D@91061|Bacilli,1ZAUE@1386|Bacillus 91061|Bacilli GM GDP-mannose 4,6 dehydratase - - - - - - - - - - - - Epimerase k141_2714_1 1116375.VEJY3_11425 5.78e-306 844.0 COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,1RMY5@1236|Gammaproteobacteria,1XTPD@135623|Vibrionales 135623|Vibrionales O Cytochrome c-type biogenesis protein ccmF ccmF - - ko:K02198 - - - - ko00000,ko02000 9.B.14.1 - - CcmF_C,Cytochrom_C_asm k141_2714_2 1116375.VEJY3_11430 7.37e-107 308.0 COG2332@1|root,COG2332@2|Bacteria,1RHN5@1224|Proteobacteria,1S5VA@1236|Gammaproteobacteria,1XU2B@135623|Vibrionales 135623|Vibrionales O Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH ccmE GO:0003674,GO:0003824,GO:0008150,GO:0009987,GO:0016043,GO:0017004,GO:0022607,GO:0034622,GO:0043933,GO:0044085,GO:0065003,GO:0071840 - ko:K02197 - - - - ko00000 - - - CcmE k141_2714_3 1116375.VEJY3_11435 1.99e-38 128.0 COG3114@1|root,COG3114@2|Bacteria,1NGBM@1224|Proteobacteria,1SGGH@1236|Gammaproteobacteria,1XYX8@135623|Vibrionales 135623|Vibrionales U Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes ccmD - - ko:K02196 ko02010,map02010 - - - ko00000,ko00001,ko02000 3.A.1.107 - - CcmD k141_2714_4 1116375.VEJY3_11440 1.76e-179 499.0 COG0755@1|root,COG0755@2|Bacteria,1MU61@1224|Proteobacteria,1RP3R@1236|Gammaproteobacteria,1XSSK@135623|Vibrionales 135623|Vibrionales U Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes ccmC - - ko:K02195 ko02010,map02010 M00259 - - ko00000,ko00001,ko00002,ko02000 3.A.1.107 - - Cytochrom_C_asm k141_2714_5 1116375.VEJY3_11445 2.82e-134 383.0 COG2386@1|root,COG2386@2|Bacteria,1NJB0@1224|Proteobacteria,1RRFJ@1236|Gammaproteobacteria,1XSZY@135623|Vibrionales 135623|Vibrionales U Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes ccmB - - ko:K02194 ko02010,map02010 M00259 - - ko00000,ko00001,ko00002,ko02000 3.A.1.107 - - CcmB k141_2714_6 1116375.VEJY3_11450 2.94e-139 394.0 COG4133@1|root,COG4133@2|Bacteria,1MZPC@1224|Proteobacteria,1S3R2@1236|Gammaproteobacteria,1XTSS@135623|Vibrionales 135623|Vibrionales P once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system ccmA GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0015232,GO:0015886,GO:0022857,GO:0051179,GO:0051181,GO:0051184,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:1901678 3.6.3.41 ko:K02193 ko02010,map02010 M00259 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.107 - - ABC_tran k141_2714_7 223926.28807217 7.98e-86 256.0 2ER47@1|root,33IPS@2|Bacteria,1NHAY@1224|Proteobacteria,1SH4T@1236|Gammaproteobacteria,1XX51@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF2802) - - - - - - - - - - - - DUF2802 k141_2714_8 1280001.BAOA01000009_gene4155 9.24e-107 308.0 COG0835@1|root,COG0835@2|Bacteria,1RAH1@1224|Proteobacteria,1SYDF@1236|Gammaproteobacteria,1XSQC@135623|Vibrionales 135623|Vibrionales NT COG0835 Chemotaxis signal transduction protein cheW - - ko:K03408 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - CheW k141_2714_9 1280001.BAOA01000009_gene4156 4.79e-99 296.0 COG0835@1|root,COG0835@2|Bacteria,1MYHY@1224|Proteobacteria,1S2TC@1236|Gammaproteobacteria,1XTG9@135623|Vibrionales 135623|Vibrionales NT Two component signalling adaptor domain VP2226 - - ko:K03408 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - CheW k141_35929_1 218284.CCDN010000006_gene3709 1.64e-61 196.0 COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,4HBIR@91061|Bacilli,1ZAQH@1386|Bacillus 91061|Bacilli S protein conserved in bacteria degV - - - - - - - - - - - DegV k141_1454_1 218284.CCDN010000010_gene4380 1.45e-123 352.0 COG0250@1|root,COG0250@2|Bacteria,1TR3P@1239|Firmicutes,4HAJA@91061|Bacilli,1ZBRH@1386|Bacillus 91061|Bacilli K Participates in transcription elongation, termination and antitermination nusG GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K02601 - - - - ko00000,ko03009,ko03021 - - - KOW,NusG k141_20455_1 1453501.JELR01000002_gene313 2.25e-145 412.0 COG0640@1|root,COG0640@2|Bacteria,1RBZC@1224|Proteobacteria,1S2VD@1236|Gammaproteobacteria,4690X@72275|Alteromonadaceae 1236|Gammaproteobacteria K Transcriptional regulator - - - - - - - - - - - - - k141_21727_1 1096930.L284_11575 2.77e-14 68.6 2CCJF@1|root,32RVW@2|Bacteria,1MZUN@1224|Proteobacteria,2UC2W@28211|Alphaproteobacteria,2K5WW@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - k141_21727_2 1042377.AFPJ01000043_gene892 1.32e-86 259.0 COG0454@1|root,COG0456@2|Bacteria,1QU0C@1224|Proteobacteria,1S503@1236|Gammaproteobacteria 1236|Gammaproteobacteria K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - - - - - - - - - - Acetyltransf_1 k141_34972_1 1384049.CD29_19170 3.65e-18 85.5 2EUS4@1|root,33N7Q@2|Bacteria,1VKV1@1239|Firmicutes,4HRK2@91061|Bacilli,3IZZD@400634|Lysinibacillus 91061|Bacilli S Toxin SpoIISA, type II toxin-antitoxin system - - - - - - - - - - - - SpoIISA_toxin k141_20654_1 1232683.ADIMK_2963 3.92e-89 271.0 COG1294@1|root,COG1294@2|Bacteria,1MURP@1224|Proteobacteria,1RP7F@1236|Gammaproteobacteria,4658Z@72275|Alteromonadaceae 1236|Gammaproteobacteria C oxidase, subunit cydB GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0016682,GO:0019646,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0070069,GO:0071944,GO:0097159,GO:1901363 1.10.3.14 ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 - iPC815.YPO1118 Cyt_bd_oxida_II k141_10085_1 863365.XHC_4424 2.9e-16 81.3 COG1595@1|root,COG1595@2|Bacteria,1N6SV@1224|Proteobacteria,1S570@1236|Gammaproteobacteria,1X6UZ@135614|Xanthomonadales 135614|Xanthomonadales K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_18409_1 1042377.AFPJ01000009_gene166 1.33e-67 211.0 COG4508@1|root,COG4508@2|Bacteria,1RAX1@1224|Proteobacteria,1RYFG@1236|Gammaproteobacteria,465HS@72275|Alteromonadaceae 1236|Gammaproteobacteria S dUTPase dut - - - - - - - - - - - dUTPase_2 k141_1610_1 1294265.JCM21738_5139 1.48e-69 212.0 COG1719@1|root,COG1719@2|Bacteria,1VD7N@1239|Firmicutes,4HKV3@91061|Bacilli,1ZH1A@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2507) yslB - - - - - - - - - - - DUF2507 k141_37257_2 1453501.JELR01000001_gene3264 0.0 925.0 COG0204@1|root,COG0204@2|Bacteria,1MWDY@1224|Proteobacteria,1RRXF@1236|Gammaproteobacteria,464IC@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG0477 Permeases of the major facilitator superfamily aas - 2.3.1.40,6.2.1.20 ko:K05939 ko00071,ko00564,map00071,map00564 - R01406,R04864 RC00014,RC00039,RC00041 ko00000,ko00001,ko01000 - - - Acyltransferase,MFS_1 k141_37257_3 1249975.JQLP01000005_gene780 1.88e-23 95.9 2CDPK@1|root,32RR8@2|Bacteria,4NSHW@976|Bacteroidetes,1I402@117743|Flavobacteriia,2P7N8@244698|Gillisia 976|Bacteroidetes - - - - - - - - - - - - - - - k141_37257_5 1042377.AFPJ01000035_gene2654 3.25e-261 723.0 COG0334@1|root,COG0334@2|Bacteria,1MUMF@1224|Proteobacteria,1RPUZ@1236|Gammaproteobacteria,4649P@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the Glu Leu Phe Val dehydrogenases family gdhA GO:0003674,GO:0003824,GO:0004353,GO:0004354,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.4 ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 - R00248 RC00006,RC02799 ko00000,ko00001,ko01000 - - iECH74115_1262.ECH74115_2481,iECSP_1301.ECSP_2329,iECs_1301.ECs2467,iG2583_1286.G2583_2207,iPC815.YPO3971,iSDY_1059.SDY_1514,iYL1228.KPN_01210,iZ_1308.Z2793 ELFV_dehydrog,ELFV_dehydrog_N k141_37257_6 1283300.ATXB01000001_gene1127 2.65e-272 748.0 COG0151@1|root,COG0151@2|Bacteria,1QYQZ@1224|Proteobacteria,1T41Z@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Belongs to the GarS family - - - - - - - - - - - - - k141_37257_7 1283300.ATXB01000001_gene419 9.69e-280 788.0 2C593@1|root,2Z84R@2|Bacteria,1Q8PC@1224|Proteobacteria,1RP26@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_19522_1 223926.28807805 1.25e-120 356.0 COG1012@1|root,COG1012@2|Bacteria,1MV2I@1224|Proteobacteria,1RPQW@1236|Gammaproteobacteria,1XTD0@135623|Vibrionales 135623|Vibrionales C Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate astD GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.2.1.71 ko:K06447 ko00330,ko01100,map00330,map01100 - R05049 RC00080 ko00000,ko00001,ko01000 - - - Aldedh k141_6479_2 1116375.VEJY3_23446 0.0 1479.0 COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,1RMPC@1236|Gammaproteobacteria,1XSB9@135623|Vibrionales 135623|Vibrionales O Belongs to the peptidase S16 family - - - - - - - - - - - - AAA_32,Lon_C k141_6479_3 1116375.VEJY3_23451 3.64e-91 269.0 2B2ED@1|root,31UYZ@2|Bacteria,1QJPI@1224|Proteobacteria,1THQG@1236|Gammaproteobacteria,1XX65@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_32448_1 218284.CCDN010000001_gene1328 1.58e-122 363.0 COG5002@1|root,COG5002@2|Bacteria,1TPSK@1239|Firmicutes,4HAH5@91061|Bacilli,1ZB8J@1386|Bacillus 91061|Bacilli T Histidine kinase arlS GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 2.7.13.3 ko:K18940 ko02020,map02020 M00716,M00717 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA k141_32448_2 218284.CCDN010000001_gene1327 1.31e-127 366.0 COG0745@1|root,COG0745@2|Bacteria,1TS81@1239|Firmicutes,4H9NE@91061|Bacilli,1ZD1X@1386|Bacillus 91061|Bacilli T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain csrR - - - - - - - - - - - Response_reg,Trans_reg_C k141_15908_1 1034347.CAHJ01000039_gene4766 5.51e-10 58.2 COG1827@1|root,COG1827@2|Bacteria,1V6EY@1239|Firmicutes,4HGYB@91061|Bacilli,1ZGFK@1386|Bacillus 91061|Bacilli S small molecule binding protein (contains 3H domain) yrxA - - ko:K07105 - - - - ko00000 - - - 3H,HTH_11 k141_15908_2 866895.HBHAL_4780 1.88e-42 151.0 COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,4H9TI@91061|Bacilli,3ND4C@45667|Halobacillus 91061|Bacilli I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol cls - - ko:K06131 ko00564,ko01100,map00564,map01100 - R07390 RC00017 ko00000,ko00001,ko01000 - - - PLDc_2,PLDc_N k141_638_1 42565.FP66_13965 1.42e-161 469.0 COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,1RPC3@1236|Gammaproteobacteria,1XJ5H@135619|Oceanospirillales 135619|Oceanospirillales C Belongs to the heme-copper respiratory oxidase family cyoB - 1.10.3.10 ko:K02298 ko00190,ko01100,map00190,map01100 M00417 R11335 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.5 - - COX1 k141_20655_1 218284.CCDN010000005_gene3353 1.94e-107 339.0 COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,4HAFP@91061|Bacilli,1ZBJ3@1386|Bacillus 91061|Bacilli V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran k141_8881_1 997296.PB1_15794 4.72e-65 204.0 COG0850@1|root,COG0850@2|Bacteria,1VAPC@1239|Firmicutes,4HBTI@91061|Bacilli,1ZDSJ@1386|Bacillus 91061|Bacilli D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization minC GO:0000910,GO:0003674,GO:0004857,GO:0007049,GO:0007105,GO:0008150,GO:0009987,GO:0022402,GO:0030234,GO:0031333,GO:0032271,GO:0032272,GO:0032506,GO:0043086,GO:0043254,GO:0044087,GO:0044092,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0065007,GO:0065009,GO:0098772 - ko:K03610 - - - - ko00000,ko03036,ko04812 - - - MinC_C k141_37258_1 1121921.KB898706_gene2447 3.84e-99 315.0 2DB7A@1|root,2Z7KK@2|Bacteria,1PI5G@1224|Proteobacteria,1RQHS@1236|Gammaproteobacteria,2PN9I@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria S Glycosyl hydrolase family 115 - - - - - - - - - - - - Glyco_hydro_115,Glyco_hydro_67N k141_25523_1 1279017.AQYJ01000029_gene3324 1.39e-126 379.0 COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,1RMPG@1236|Gammaproteobacteria,464P1@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG0514 Superfamily II DNA helicase recQ - 3.6.4.12 ko:K03654 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind k141_20656_1 1286106.MPL1_09040 3.62e-51 174.0 COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,1MU60@1224|Proteobacteria,1RNRD@1236|Gammaproteobacteria,4607C@72273|Thiotrichales 72273|Thiotrichales E Prephenate dehydratase pheA - 4.2.1.51,5.4.99.5 ko:K04518,ko:K14170 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024,M00025 R00691,R01373,R01715 RC00360,RC03116 ko00000,ko00001,ko00002,ko01000 - - - ACT,CM_2,PDT k141_19523_2 1453501.JELR01000001_gene3255 5.47e-88 259.0 COG0848@1|root,COG0848@2|Bacteria,1RHQ3@1224|Proteobacteria,1S7BK@1236|Gammaproteobacteria,468UQ@72275|Alteromonadaceae 1236|Gammaproteobacteria U Biopolymer transport protein ExbD/TolR - - - ko:K03559 - - - - ko00000,ko02000 1.A.30.2.1 - - ExbD k141_15909_1 247490.KSU1_B0268 3.35e-73 241.0 COG1271@1|root,COG1271@2|Bacteria 2|Bacteria C aerobic electron transport chain - - 1.10.3.14 ko:K00425,ko:K08738 ko00190,ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00190,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416 M00153,M00595 R10151,R11325 RC00061,RC03151,RC03152 ko00000,ko00001,ko00002,ko01000 3.D.4.3,3.D.4.6 - - Cyt_bd_oxida_I,Cytochrome_CBB3 k141_6500_1 1294265.JCM21738_187 9.38e-74 225.0 COG3278@1|root,COG3278@2|Bacteria,1V1DN@1239|Firmicutes,4HAMA@91061|Bacilli,1ZD10@1386|Bacillus 91061|Bacilli O Belongs to the heme-copper respiratory oxidase family - - - - - - - - - - - - - k141_6500_2 1294265.JCM21738_186 4.69e-24 92.4 COG2151@1|root,COG2151@2|Bacteria,1V9YV@1239|Firmicutes,4HKC6@91061|Bacilli,1ZH20@1386|Bacillus 91061|Bacilli S Iron-sulfur cluster assembly protein - - - - - - - - - - - - FeS_assembly_P k141_19549_1 1219626.HMPREF1639_02090 1.47e-50 177.0 COG0446@1|root,COG0607@1|root,COG0446@2|Bacteria,COG0607@2|Bacteria,1TPWW@1239|Firmicutes,2484C@186801|Clostridia,25QTC@186804|Peptostreptococcaceae 186801|Clostridia P Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain cdr - - - - - - - - - - - DrsE_2,Pyr_redox_2,Pyr_redox_dim,Rhodanese,TusA k141_13733_1 42565.FP66_08220 1.61e-117 346.0 COG0523@1|root,COG0523@2|Bacteria,1MVZV@1224|Proteobacteria,1RQDY@1236|Gammaproteobacteria,1XI09@135619|Oceanospirillales 135619|Oceanospirillales S Cobalamin synthesis protein P47K - - - - - - - - - - - - CobW_C,cobW k141_14698_1 1347086.CCBA010000023_gene2185 8.78e-87 257.0 2ECKJ@1|root,336IM@2|Bacteria,1U9IB@1239|Firmicutes,4IJNY@91061|Bacilli,1ZCP1@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_23208_1 1078085.HMPREF1210_02866 4.42e-30 122.0 COG1404@1|root,COG1404@2|Bacteria,1TPH1@1239|Firmicutes,4HBQH@91061|Bacilli 91061|Bacilli O Belongs to the peptidase S8 family prtS - 3.4.21.110,3.4.21.96 ko:K01361,ko:K08652 - - - - ko00000,ko01000,ko01002,ko03110 - - - FIVAR,Gram_pos_anchor,Inhibitor_I9,PA,Peptidase_S8,SLH,YSIRK_signal,fn3_5 k141_1629_1 1117647.M5M_14040 4.34e-54 174.0 COG3310@1|root,COG3310@2|Bacteria,1RDE0@1224|Proteobacteria,1S3X6@1236|Gammaproteobacteria,1J6IR@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria - - - ko:K09941 - - - - ko00000 - - - DUF1415 k141_1629_2 1279017.AQYJ01000029_gene3397 1.92e-28 110.0 COG4667@1|root,COG4667@2|Bacteria,1PV7M@1224|Proteobacteria,1RRPR@1236|Gammaproteobacteria,464M0@72275|Alteromonadaceae 1236|Gammaproteobacteria S esterase of the alpha-beta hydrolase superfamily - - - - - - - - - - - - Patatin k141_25556_1 1229783.C273_07302 2.73e-06 55.5 COG5384@1|root,COG5644@1|root,COG5384@2|Bacteria,COG5644@2|Bacteria 2|Bacteria H endopeptidase inhibitor activity yddG - - ko:K03201,ko:K13613 ko03070,map03070 M00333 - - ko00000,ko00001,ko00002,ko01004,ko01008,ko02044 3.A.7 - - CHU_C,IgGFc_binding,Laminin_G_3 k141_23209_1 1034769.KB910518_gene3176 9.79e-48 162.0 COG2207@1|root,COG3708@1|root,COG2207@2|Bacteria,COG3708@2|Bacteria,1TPI9@1239|Firmicutes,4HCJ8@91061|Bacilli,26RU3@186822|Paenibacillaceae 91061|Bacilli K AraC family transcriptional regulator ydeE7 - - ko:K13653 - - - - ko00000,ko03000 - - - Cass2,GyrI-like,HTH_18 k141_21905_1 218284.CCDN010000010_gene4374 3.59e-179 532.0 COG0085@1|root,COG0085@2|Bacteria,1TP96@1239|Firmicutes,4H9PK@91061|Bacilli,1ZBPC@1386|Bacillus 91061|Bacilli K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoB GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 k141_5334_2 218284.CCDN010000005_gene3469 1.75e-67 205.0 COG3564@1|root,COG3564@2|Bacteria,1V81N@1239|Firmicutes,4HIP2@91061|Bacilli,1ZHIC@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF779) - - - ko:K09959 - - - - ko00000 - - - DUF779 k141_7576_1 1294265.JCM21738_1253 4.62e-111 330.0 COG1366@1|root,COG1366@2|Bacteria,1UNBX@1239|Firmicutes,4HEFW@91061|Bacilli,1ZAYN@1386|Bacillus 91061|Bacilli T Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor) - - - ko:K17763 - - - - ko00000,ko03021 - - - STAS k141_35011_1 218284.CCDN010000001_gene170 1.93e-64 214.0 COG2304@1|root,COG2304@2|Bacteria,1V0C8@1239|Firmicutes,4HDR1@91061|Bacilli,1ZCG8@1386|Bacillus 91061|Bacilli S Aerotolerance regulator N-terminal - - - - - - - - - - - - BatA,VWA_2 k141_36061_1 1453501.JELR01000002_gene351 2.68e-72 221.0 2B4XH@1|root,32REP@2|Bacteria,1RJ9F@1224|Proteobacteria,1T0SV@1236|Gammaproteobacteria,46BPI@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_36061_2 1279017.AQYJ01000026_gene66 2.12e-308 861.0 COG0457@1|root,COG0457@2|Bacteria,1MXSS@1224|Proteobacteria,1S157@1236|Gammaproteobacteria,46CPY@72275|Alteromonadaceae 1236|Gammaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16 k141_36061_3 1453501.JELR01000002_gene349 1.23e-151 464.0 COG4105@1|root,COG4105@2|Bacteria,1QVQ9@1224|Proteobacteria,1RSIG@1236|Gammaproteobacteria,46DC5@72275|Alteromonadaceae 1236|Gammaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16,TPR_6 k141_25557_1 546271.Selsp_0724 6.31e-55 189.0 COG0449@1|root,COG0449@2|Bacteria,1TPGU@1239|Firmicutes,4H1ZJ@909932|Negativicutes 909932|Negativicutes M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source glmS - 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 - R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 - - - GATase_6,SIS k141_14699_1 1415166.NONO_c31840 8.04e-14 70.9 COG0558@1|root,COG0558@2|Bacteria,2GM3F@201174|Actinobacteria,4FXAB@85025|Nocardiaceae 201174|Actinobacteria I Belongs to the CDP-alcohol phosphatidyltransferase class-I family pgsA2 GO:0003674,GO:0003824,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 - R01801,R02030 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 - - - CDP-OH_P_transf k141_6501_1 1042377.AFPJ01000030_gene447 6.82e-103 322.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MV8W@1224|Proteobacteria,1RMQA@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Outer membrane receptor proteins mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec k141_25558_1 218284.CCDN010000001_gene225 6.19e-38 132.0 COG3874@1|root,COG3874@2|Bacteria,1V6H7@1239|Firmicutes,4HIG7@91061|Bacilli,1ZG9C@1386|Bacillus 91061|Bacilli S Sporulation protein YtfJ ytfJ - - - - - - - - - - - Spore_YtfJ k141_30112_1 1453501.JELR01000001_gene1925 3.22e-284 794.0 COG1506@1|root,COG1506@2|Bacteria,1MUJ3@1224|Proteobacteria,1RPAW@1236|Gammaproteobacteria,464D0@72275|Alteromonadaceae 1236|Gammaproteobacteria E X-Pro dipeptidyl-peptidase (S15 family) - - - - - - - - - - - - Peptidase_S9 k141_2834_1 1116375.VEJY3_19291 4.62e-127 364.0 COG1028@1|root,COG1028@2|Bacteria,1N907@1224|Proteobacteria,1S0GV@1236|Gammaproteobacteria,1XTGE@135623|Vibrionales 135623|Vibrionales IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 k141_2834_2 1348635.BBJY01000001_gene2415 5.34e-238 662.0 COG0534@1|root,COG0534@2|Bacteria,1MVRV@1224|Proteobacteria,1RRDQ@1236|Gammaproteobacteria,1XYN5@135623|Vibrionales 135623|Vibrionales V MatE - - - - - - - - - - - - MatE k141_5336_1 1307436.PBF_19113 7.82e-09 51.6 29SC3@1|root,30DGP@2|Bacteria,1UB9T@1239|Firmicutes,4IMNJ@91061|Bacilli,1ZKHE@1386|Bacillus 91061|Bacilli S Putative methionine and alanine importer, small subunit - - - - - - - - - - - - MaAIMP_sms k141_13737_1 218284.CCDN010000002_gene2609 3.7e-36 133.0 COG1173@1|root,COG1173@2|Bacteria,1V21B@1239|Firmicutes,4HJ5Y@91061|Bacilli,1ZFPK@1386|Bacillus 91061|Bacilli EP ABC transporter (permease) - - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 k141_655_1 218284.CCDN010000002_gene2479 1.32e-107 322.0 COG2368@1|root,COG2368@2|Bacteria,1TQ70@1239|Firmicutes,4HA4I@91061|Bacilli,1ZDRC@1386|Bacillus 91061|Bacilli Q COG2368 Aromatic ring hydroxylase hpaH - 1.14.14.8,1.14.14.9 ko:K00483,ko:K16901 ko00350,ko00380,ko01120,ko01220,map00350,map00380,map01120,map01220 - R02698,R03299,R09517 RC00046 ko00000,ko00001,ko01000 - - - HpaB,HpaB_N k141_655_2 218284.CCDN010000002_gene2478 1.87e-133 380.0 COG0664@1|root,COG0664@2|Bacteria,1UZI5@1239|Firmicutes,4HF6U@91061|Bacilli,1ZFY0@1386|Bacillus 91061|Bacilli K COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - - - - - - - - - - HTH_Crp_2,cNMP_binding k141_655_3 218284.CCDN010000002_gene2477 6.83e-82 246.0 COG0664@1|root,COG0664@2|Bacteria,1V2MA@1239|Firmicutes,4HGGW@91061|Bacilli,1ZG6D@1386|Bacillus 91061|Bacilli K COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - - - - - - - - - - HTH_Crp_2,cNMP_binding k141_29009_1 1397693.KK211187_gene2978 1.79e-101 307.0 COG2610@1|root,COG2610@2|Bacteria,1TQ14@1239|Firmicutes,4HB0Y@91061|Bacilli 91061|Bacilli EG Gluconate - - - ko:K03299 - - - - ko00000,ko02000 2.A.8 - - GntP_permease k141_14700_1 218284.CCDN010000001_gene1943 6.48e-63 197.0 COG1670@1|root,COG1670@2|Bacteria,1V1G0@1239|Firmicutes,4HG29@91061|Bacilli,1ZQ70@1386|Bacillus 91061|Bacilli J Acetyltransferase (GNAT) domain - - 2.3.1.82 ko:K00663 - - - - ko00000,ko01000,ko01504 - - - Acetyltransf_8 k141_27703_2 1279017.AQYJ01000022_gene2602 3.36e-135 388.0 COG1024@1|root,COG1024@2|Bacteria,1Q67Q@1224|Proteobacteria,1S1Z5@1236|Gammaproteobacteria,466W9@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1024 Enoyl-CoA hydratase carnithine racemase - - - - - - - - - - - - ECH_1 k141_26879_2 1116375.VEJY3_22316 3.67e-23 89.4 28VN4@1|root,2ZHQ8@2|Bacteria,1P4YK@1224|Proteobacteria,1SU6C@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_26879_3 1116375.VEJY3_22326 3.67e-235 649.0 COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,1RM8U@1236|Gammaproteobacteria,1XSJM@135623|Vibrionales 135623|Vibrionales M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids - - 5.1.1.1 ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 - R00401 RC00285 ko00000,ko00001,ko01000,ko01011 - - - Ala_racemase_C,Ala_racemase_N k141_26879_4 1116375.VEJY3_22331 2.57e-227 627.0 COG3367@1|root,COG3367@2|Bacteria,1MVEX@1224|Proteobacteria,1RNVG@1236|Gammaproteobacteria,1XT33@135623|Vibrionales 135623|Vibrionales S Domain of unknown function (DUF1611_N) Rossmann-like domain - - - - - - - - - - - - DUF1611,DUF1611_N k141_7578_1 997346.HMPREF9374_2775 1.8e-30 122.0 COG2304@1|root,COG2304@2|Bacteria,1UZKX@1239|Firmicutes,4HCSC@91061|Bacilli,27CQ0@186824|Thermoactinomycetaceae 91061|Bacilli S von Willebrand factor (vWF) type A domain - - - - - - - - - - - - VWA k141_30113_1 1453501.JELR01000002_gene806 4.6e-117 353.0 COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,1RMGA@1236|Gammaproteobacteria,46478@72275|Alteromonadaceae 1236|Gammaproteobacteria L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG GO:0003674,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB_bind,DnaG_DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2 k141_25559_1 218284.CCDN010000001_gene561 1.7e-161 454.0 COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,4HB73@91061|Bacilli,1ZCKH@1386|Bacillus 91061|Bacilli I Belongs to the enoyl-CoA hydratase isomerase family fadB GO:0003674,GO:0003824,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 4.2.1.17 ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 M00087 R03026,R04170,R04738,R04740,R04744,R04746 RC00831,RC01095 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 k141_2835_1 326423.RBAM_016530 2.44e-113 345.0 COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,4H9Z3@91061|Bacilli,1ZB24@1386|Bacillus 91061|Bacilli J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction pnp GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 M00394 R00437,R00438,R00439,R00440 RC02795 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 - - - KH_1,PNPase,RNase_PH,RNase_PH_C,S1 k141_5338_1 398767.Glov_2399 4.71e-07 52.0 COG1924@1|root,COG1924@2|Bacteria,1R6HU@1224|Proteobacteria,42RWX@68525|delta/epsilon subdivisions,2WNC9@28221|Deltaproteobacteria,43V8M@69541|Desulfuromonadales 28221|Deltaproteobacteria I BadF/BadG/BcrA/BcrD ATPase family yjiL - - - - - - - - - - - BcrAD_BadFG k141_5338_2 398767.Glov_2398 2.21e-39 140.0 COG1924@1|root,COG1924@2|Bacteria,1R6HU@1224|Proteobacteria,42R04@68525|delta/epsilon subdivisions,2WMZ2@28221|Deltaproteobacteria 28221|Deltaproteobacteria I PFAM ATPase, BadF BadG BcrA BcrD type - - - - - - - - - - - - BcrAD_BadFG k141_36062_1 1453501.JELR01000002_gene579 3.92e-121 377.0 COG0642@1|root,COG0784@1|root,COG1457@1|root,COG0784@2|Bacteria,COG1457@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1RRGT@1236|Gammaproteobacteria,464VX@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0642 Signal transduction histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,Response_reg k141_10116_1 1042377.AFPJ01000030_gene493 3.97e-131 376.0 COG1262@1|root,COG1262@2|Bacteria,1Q227@1224|Proteobacteria,1RQEK@1236|Gammaproteobacteria,467FP@72275|Alteromonadaceae 1236|Gammaproteobacteria S SapC - - - - - - - - - - - - SapC k141_10116_2 1122137.AQXF01000007_gene3600 1.86e-231 654.0 COG0644@1|root,COG0644@2|Bacteria,1R41S@1224|Proteobacteria,2TW03@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Tryptophan halogenase - - 1.14.19.9 ko:K14266 ko00404,ko01130,map00404,map01130 M00789,M00790 R09570 RC00949 ko00000,ko00001,ko00002,ko01000 - - - Trp_halogenase k141_10116_3 1122137.AQXF01000007_gene3599 1.44e-233 655.0 COG0665@1|root,COG0665@2|Bacteria,1MU40@1224|Proteobacteria,2TTKE@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Tryptophan halogenase - - - - - - - - - - - - Trp_halogenase k141_26881_1 218284.CCDN010000001_gene594 1.53e-102 317.0 COG0466@1|root,COG0466@2|Bacteria,1TNYG@1239|Firmicutes,4HAZK@91061|Bacilli,1ZAXX@1386|Bacillus 91061|Bacilli O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner lon GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.4.21.53 ko:K01338 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - AAA,LON_substr_bdg,Lon_C k141_15933_1 1517681.HW45_09845 1.31e-115 344.0 COG1129@1|root,COG1129@2|Bacteria,1MU22@1224|Proteobacteria,1RMCH@1236|Gammaproteobacteria,1XZSK@135623|Vibrionales 135623|Vibrionales G ATPases associated with a variety of cellular activities - - 3.6.3.17 ko:K10441 ko02010,map02010 M00212 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - ABC_tran k141_14701_2 218284.CCDN010000001_gene644 3.3e-107 318.0 COG0379@1|root,COG0379@2|Bacteria,1TP6R@1239|Firmicutes,4H9QG@91061|Bacilli,1ZAR3@1386|Bacillus 91061|Bacilli H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate nadA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 ko:K03517 ko00760,ko01100,map00760,map01100 M00115 R04292 RC01119 ko00000,ko00001,ko00002,ko01000 - - - NadA k141_30114_1 665959.HMPREF1013_03891 2.67e-40 138.0 COG0344@1|root,COG0344@2|Bacteria,1VA3J@1239|Firmicutes,4HC55@91061|Bacilli,1ZFP9@1386|Bacillus 91061|Bacilli I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP plsY - 2.3.1.15 ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - G3P_acyltransf k141_32477_2 1453501.JELR01000002_gene920 3.66e-117 340.0 COG1272@1|root,COG1272@2|Bacteria,1PGRH@1224|Proteobacteria,1RR4R@1236|Gammaproteobacteria,467AP@72275|Alteromonadaceae 1236|Gammaproteobacteria S membrane protein, hemolysin III homolog yqfA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K11068 - - - - ko00000,ko02042 - - - HlyIII k141_656_1 1347369.CCAD010000075_gene3202 2.12e-134 406.0 COG1595@1|root,COG1595@2|Bacteria,1U9I0@1239|Firmicutes,4IJNF@91061|Bacilli,1ZC9D@1386|Bacillus 91061|Bacilli K Domain of unknown function (DUF4179) - - - - - - - - - - - - DUF4179,Sigma70_r4,Sigma70_r4_2,zf-HC2 k141_7580_1 886379.AEWI01000034_gene3030 4.87e-66 211.0 COG3001@1|root,COG3001@2|Bacteria,4NEQY@976|Bacteroidetes,2FTFQ@200643|Bacteroidia,3XJIF@558415|Marinilabiliaceae 976|Bacteroidetes G Fructosamine kinase - - - - - - - - - - - - Fructosamin_kin k141_10117_1 1209072.ALBT01000052_gene589 9.75e-19 84.7 COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,1RP4D@1236|Gammaproteobacteria,1FFV0@10|Cellvibrio 1236|Gammaproteobacteria E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine trpB GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - PALP k141_10117_2 498211.CJA_1750 4.48e-81 247.0 COG0135@1|root,COG0135@2|Bacteria,1RA87@1224|Proteobacteria,1S41P@1236|Gammaproteobacteria,1FH9J@10|Cellvibrio 1236|Gammaproteobacteria E N-(5'phosphoribosyl)anthranilate (PRA) isomerase trpF - 5.3.1.24 ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03509 RC00945 ko00000,ko00001,ko00002,ko01000 - - - PRAI k141_8909_1 218284.CCDN010000007_gene3874 4.07e-167 472.0 COG0714@1|root,COG0714@2|Bacteria,1V1P5@1239|Firmicutes,4HG3W@91061|Bacilli,1ZBKT@1386|Bacillus 91061|Bacilli S ATPase family associated with various cellular activities (AAA) gvpN - - - - - - - - - - - AAA_5 k141_2837_1 218284.CCDN010000001_gene734 1.69e-88 277.0 COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,4HA9S@91061|Bacilli,1ZAZ2@1386|Bacillus 91061|Bacilli O Heat shock 70 kDa protein dnaK GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0030246,GO:0030247,GO:0044464,GO:0051704,GO:0098630,GO:0098743,GO:2001065 - ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 - - HSP70 k141_29011_2 1294265.JCM21738_298 4.04e-32 117.0 COG1766@1|root,COG1766@2|Bacteria,1TRK0@1239|Firmicutes,4HBF0@91061|Bacilli,1ZAZN@1386|Bacillus 91061|Bacilli N The M ring may be actively involved in energy transduction fliF - - ko:K02409 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 - - YscJ_FliF,YscJ_FliF_C k141_36063_1 218284.CCDN010000001_gene1873 1.32e-141 415.0 COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,4HAAP@91061|Bacilli,1ZB4E@1386|Bacillus 91061|Bacilli S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay rnjB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 - ko:K12574 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - Lactamase_B,RMMBL k141_27704_1 218284.CCDN010000001_gene807 1.3e-70 227.0 COG2866@1|root,COG2866@2|Bacteria,1TP3K@1239|Firmicutes,4HAHN@91061|Bacilli,1ZD1J@1386|Bacillus 91061|Bacilli E Gamma-D-glutamyl-L-diamino acid endopeptidase yqgT GO:0003674,GO:0003824,GO:0004180,GO:0004181,GO:0005575,GO:0005576,GO:0005615,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0044421,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.19.11 ko:K01308 - - - - ko00000,ko01000,ko01002 - - - LysM,Peptidase_M14 k141_27704_2 218284.CCDN010000001_gene806 7.56e-111 336.0 COG1368@1|root,COG1368@2|Bacteria,1TRMA@1239|Firmicutes,4H9S0@91061|Bacilli,1ZBBV@1386|Bacillus 91061|Bacilli M Belongs to the LTA synthase family yqgS - 2.7.8.20 ko:K01138,ko:K19005 ko00561,ko01100,map00561,map01100 - R05081,R10849 RC00017 ko00000,ko00001,ko01000 - - - Sulfatase k141_18424_1 223926.28807807 6.05e-172 486.0 COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,1RMV1@1236|Gammaproteobacteria,1XSTJ@135623|Vibrionales 135623|Vibrionales E acetylornithine aminotransferase argD GO:0003674,GO:0003824,GO:0003992,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.11,2.6.1.17 ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R02283,R04475 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 k141_18424_2 1280001.BAOA01000039_gene2499 8.02e-134 380.0 COG0512@1|root,COG0512@2|Bacteria,1MV5Y@1224|Proteobacteria,1RMQW@1236|Gammaproteobacteria,1XUV5@135623|Vibrionales 135623|Vibrionales EH COG0512 Anthranilate para-aminobenzoate synthases component II pabA - 2.6.1.85 ko:K01664 ko00790,map00790 - R01716 RC00010,RC01418 ko00000,ko00001,ko01000 - - - GATase k141_11304_1 926692.AZYG01000041_gene1606 2.79e-18 83.6 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,3WAAG@53433|Halanaerobiales 186801|Clostridia J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis tuf - - ko:K02358 - - - - ko00000,ko03012,ko03029,ko04147 - - - GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 k141_37448_4 223926.28806144 6.15e-42 138.0 2E5ME@1|root,330CB@2|Bacteria,1N8G6@1224|Proteobacteria,1SC9I@1236|Gammaproteobacteria,1XYC2@135623|Vibrionales 135623|Vibrionales S Phosphate-starvation-inducible E - - - - - - - - - - - - PsiE k141_37448_5 223926.28806145 5.86e-193 536.0 COG2116@1|root,COG2116@2|Bacteria,1MU0W@1224|Proteobacteria,1RQ6K@1236|Gammaproteobacteria,1XUCS@135623|Vibrionales 135623|Vibrionales P COG2116 Formate nitrite family of transporters focA - - ko:K06212 - - - - ko00000,ko02000 1.A.16.1.1,1.A.16.1.3 - - Form_Nir_trans k141_37448_6 1116375.VEJY3_05645 7.82e-24 90.1 2AWYR@1|root,31NWG@2|Bacteria,1QKK1@1224|Proteobacteria,1TIQA@1236|Gammaproteobacteria,1XZG7@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_37448_7 1116375.VEJY3_05650 1.5e-142 407.0 COG0390@1|root,COG0390@2|Bacteria,1MV2N@1224|Proteobacteria,1RSGA@1236|Gammaproteobacteria,1XT6E@135623|Vibrionales 135623|Vibrionales S transport system, permease component - - - ko:K02069 - M00211 - - ko00000,ko00002,ko02000 9.B.25.1 - - UPF0014 k141_37448_8 1116375.VEJY3_05655 9.98e-35 118.0 COG4459@1|root,COG4459@2|Bacteria,1NGRU@1224|Proteobacteria,1SGMN@1236|Gammaproteobacteria,1XYWD@135623|Vibrionales 135623|Vibrionales C COG4459 Periplasmic nitrate reductase system, NapE component torE - - ko:K02571 - - - - ko00000 - - - NapE k141_37448_9 1116375.VEJY3_05660 3.37e-292 796.0 COG3005@1|root,COG3005@2|Bacteria,1MWV2@1224|Proteobacteria,1RQ52@1236|Gammaproteobacteria,1XU38@135623|Vibrionales 135623|Vibrionales C Belongs to the TorC TorY family torC - - ko:K03532 ko02020,map02020 - - - ko00000,ko00001,ko02000 5.A.3.4 - - Cytochrom_NNT,DHC k141_37448_10 1116375.VEJY3_05665 0.0 1699.0 COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,1RMVE@1236|Gammaproteobacteria,1XV0F@135623|Vibrionales 135623|Vibrionales C COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing torA GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009033,GO:0009061,GO:0009322,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016657,GO:0032991,GO:0044237,GO:0045333,GO:0055114,GO:1902494 1.7.2.3 ko:K07811,ko:K07812 ko02020,map02020 - - - ko00000,ko00001,ko01000,ko02000 5.A.3.4 - - Molybdopterin,Molydop_binding,TAT_signal k141_37448_11 1219076.N646_0212 2.4e-221 618.0 COG2248@1|root,COG2248@2|Bacteria,1MVZY@1224|Proteobacteria,1RPTC@1236|Gammaproteobacteria,1XU4E@135623|Vibrionales 135623|Vibrionales S Putative, 10TM heavy-metal exporter VP1164 - - - - - - - - - - - ArsP_2 k141_37448_12 1219076.N646_0213 2.01e-212 587.0 COG1227@1|root,COG1227@2|Bacteria,1P9JN@1224|Proteobacteria,1RZSV@1236|Gammaproteobacteria,1XSNW@135623|Vibrionales 135623|Vibrionales C COG1227 Inorganic pyrophosphatase exopolyphosphatase ppaC - 3.6.1.1 ko:K15986 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - DHH,DHHA2 k141_35291_22 1219076.N646_1090 4.28e-175 489.0 COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,1RPUU@1236|Gammaproteobacteria,1Y26P@135623|Vibrionales 135623|Vibrionales C 4Fe-4S dicluster domain - - - ko:K08358 ko00920,ko01120,ko02020,map00920,map01120,map02020 - R10150 RC03109 ko00000,ko00001,ko02000 5.A.3.10 - - Fer4_11,Fer4_7 k141_35291_23 1116375.VEJY3_10465 1.94e-196 560.0 COG3221@1|root,COG4191@1|root,COG3221@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RNNF@1236|Gammaproteobacteria,1XUU5@135623|Vibrionales 135623|Vibrionales T ABC transporter, phosphonate, periplasmic substrate-binding protein - - 2.7.13.3 ko:K13040 ko02020,map02020 M00514 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,Phosphonate-bd k141_19784_1 218284.CCDN010000005_gene3367 4.36e-30 119.0 COG5002@1|root,COG5002@2|Bacteria,1VUBP@1239|Firmicutes,4HUPW@91061|Bacilli,1ZS15@1386|Bacillus 91061|Bacilli T Histidine kinase kinE - 2.7.13.3 ko:K13533 ko02020,map02020 M00485 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9 k141_3019_1 1033734.CAET01000013_gene1777 2.98e-40 144.0 COG1914@1|root,COG1914@2|Bacteria,1V04N@1239|Firmicutes,4HBF6@91061|Bacilli,1ZF5E@1386|Bacillus 91061|Bacilli P Natural resistance-associated macrophage protein mntH_2 - - - - - - - - - - - Nramp k141_3019_2 1307436.PBF_18179 1.02e-53 173.0 COG5513@1|root,COG5513@2|Bacteria,1V4PH@1239|Firmicutes,4HG7Y@91061|Bacilli,1ZG3W@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3298) - - - - - - - - - - - - DUF3298,DUF4163 k141_27903_1 218284.CCDN010000005_gene3384 3.6e-178 504.0 COG0719@1|root,COG0719@2|Bacteria,1TRT0@1239|Firmicutes,4HB6W@91061|Bacilli,1ZATY@1386|Bacillus 91061|Bacilli O assembly protein SufD sufD - - ko:K07033,ko:K09015 - - - - ko00000 - - - UPF0051 k141_17328_1 1348635.BBJY01000003_gene3793 1.1e-218 608.0 COG2966@1|root,COG3610@1|root,COG2966@2|Bacteria,COG3610@2|Bacteria,1RAQ0@1224|Proteobacteria,1RP2P@1236|Gammaproteobacteria,1XUE6@135623|Vibrionales 135623|Vibrionales S Putative threonine/serine exporter - - - - - - - - - - - - ThrE,ThrE_2 k141_5639_1 42565.FP66_00450 2.22e-126 362.0 COG0625@1|root,COG0625@2|Bacteria,1RD7K@1224|Proteobacteria,1S42S@1236|Gammaproteobacteria,1XPCN@135619|Oceanospirillales 135619|Oceanospirillales O Glutathione S-transferase, C-terminal domain - - - - - - - - - - - - GST_C_2,GST_N_3 k141_23463_1 1042377.AFPJ01000052_gene1568 4.3e-75 251.0 COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,1RMU1@1236|Gammaproteobacteria,464K7@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG1643 HrpA-like helicases hrpA GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0006139,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 3.6.4.13 ko:K03578 - - - - ko00000,ko01000 - - - DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind k141_14930_1 1211814.CAPG01000060_gene2892 1.06e-40 150.0 COG0653@1|root,COG0653@2|Bacteria,1TSCF@1239|Firmicutes,4HBNY@91061|Bacilli,1ZD65@1386|Bacillus 91061|Bacilli U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA GO:0002790,GO:0003674,GO:0005215,GO:0006810,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0022804,GO:0022857,GO:0022884,GO:0032940,GO:0033036,GO:0042886,GO:0042887,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:1904680 - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - Helicase_C,SecA_DEAD,SecA_PP_bind,SecA_SW k141_861_2 218284.CCDN010000001_gene1875 2e-14 72.0 COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,4HADX@91061|Bacilli,1ZBSQ@1386|Bacillus 91061|Bacilli E Belongs to the aspartokinase family dapG GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,ACT_7 k141_18749_1 1196031.ALEG01000029_gene3661 7.34e-108 320.0 COG0477@1|root,COG2814@2|Bacteria,1UXXX@1239|Firmicutes,4HC83@91061|Bacilli,1ZBD6@1386|Bacillus 91061|Bacilli EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1,Sugar_tr k141_35292_1 42565.FP66_11670 2.51e-134 391.0 COG1875@1|root,COG1875@2|Bacteria,1MUX1@1224|Proteobacteria,1RMQN@1236|Gammaproteobacteria,1XHDG@135619|Oceanospirillales 135619|Oceanospirillales T ATPase related to phosphate starvation-inducible protein PhoH phoH1 - - ko:K07175 - - - - ko00000 - - - PIN_4,PhoH k141_24543_1 1384054.N790_08855 4.29e-27 114.0 COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,1RN3V@1236|Gammaproteobacteria,1X46J@135614|Xanthomonadales 135614|Xanthomonadales FP Belongs to the GppA Ppx family ppx - 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 - R03409 RC00002 ko00000,ko00001,ko01000 - - - Ppx-GppA k141_24543_2 1279017.AQYJ01000028_gene2332 1.11e-276 765.0 COG0397@1|root,COG0397@2|Bacteria,1MVK3@1224|Proteobacteria,1RNCS@1236|Gammaproteobacteria,4646G@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the UPF0061 (SELO) family ydiU - - ko:K08997 - - - - ko00000 - - - UPF0061 k141_24543_3 1042377.AFPJ01000004_gene395 6.35e-68 208.0 COG4731@1|root,COG4731@2|Bacteria,1N19Y@1224|Proteobacteria,1SC9D@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Uncharacterized protein conserved in bacteria (DUF2147) - - - - - - - - - - - - DUF2147 k141_9162_1 218284.CCDN010000002_gene2851 1.89e-169 484.0 COG1649@1|root,COG1649@2|Bacteria,1TRTG@1239|Firmicutes,4HD0M@91061|Bacilli,1ZC0H@1386|Bacillus 91061|Bacilli T Glycosyl hydrolase-like 10 yngK - - - - - - - - - - - Big_2,Cu_amine_oxidN1,GHL10 k141_31428_1 218284.CCDN010000002_gene2751 7.39e-121 353.0 COG0601@1|root,COG0601@2|Bacteria,1UYTT@1239|Firmicutes,4IEZM@91061|Bacilli,1ZJ9K@1386|Bacillus 91061|Bacilli EP Binding-protein-dependent transport system inner membrane component - - - - - - - - - - - - BPD_transp_1 k141_7805_2 1034347.CAHJ01000010_gene1956 5.35e-32 124.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,1ZBXB@1386|Bacillus 91061|Bacilli V COG1132 ABC-type multidrug transport system, ATPase and permease components mdlA - - ko:K06148,ko:K18889 ko02010,map02010 M00707 - - ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.106.13,3.A.1.106.5 - - ABC_membrane,ABC_tran k141_19785_1 218284.CCDN010000004_gene3075 3.3e-153 436.0 COG0189@1|root,COG0189@2|Bacteria,1TSHN@1239|Firmicutes,4HBFG@91061|Bacilli,1ZDEU@1386|Bacillus 91061|Bacilli HJ COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase) - - - - - - - - - - - - RimK k141_36242_1 1078085.HMPREF1210_02082 6.88e-65 212.0 COG1748@1|root,COG1748@2|Bacteria,1UZ0U@1239|Firmicutes,4HBQX@91061|Bacilli 91061|Bacilli E Saccharopine dehydrogenase - - - - - - - - - - - - Sacchrp_dh_NADP k141_3020_1 1294265.JCM21738_2760 9.88e-166 473.0 COG0749@1|root,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,4H9S7@91061|Bacilli,1ZB6Y@1386|Bacillus 91061|Bacilli L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A k141_27904_2 1453501.JELR01000001_gene3012 1.83e-43 153.0 COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,1RN4V@1236|Gammaproteobacteria,4648Z@72275|Alteromonadaceae 1236|Gammaproteobacteria M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamB GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0008152,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0016491,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0042802,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0055114,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - ko:K17713 - - - - ko00000,ko02000 1.B.33.1 - - PQQ_2,PQQ_3 k141_18751_1 553217.ENHAE0001_1170 1.6e-45 163.0 COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,1RNKA@1236|Gammaproteobacteria,3NIYF@468|Moraxellaceae 1236|Gammaproteobacteria H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source nadE - 6.3.1.5,6.3.5.1 ko:K01916,ko:K01950 ko00760,ko01100,map00760,map01100 M00115 R00189,R00257 RC00010,RC00100 ko00000,ko00001,ko00002,ko01000 - - - CN_hydrolase,NAD_synthase k141_14057_1 1219076.N646_4360 1.08e-104 303.0 COG1432@1|root,COG1432@2|Bacteria,1MUAE@1224|Proteobacteria,1S47Z@1236|Gammaproteobacteria,1XW9S@135623|Vibrionales 135623|Vibrionales S NYN domain - - - - - - - - - - - - NYN k141_14057_2 1116375.VEJY3_19581 1.57e-78 236.0 2DRCR@1|root,33B8F@2|Bacteria,1NHMX@1224|Proteobacteria,1SCT6@1236|Gammaproteobacteria,1XXGC@135623|Vibrionales 135623|Vibrionales S Domain of unknown function (DUF4174) VPA0983 - - - - - - - - - - - DUF4174 k141_14057_3 1219076.N646_4362 3.77e-166 466.0 COG0007@1|root,COG0007@2|Bacteria,1MUI0@1224|Proteobacteria,1RM9V@1236|Gammaproteobacteria,1XSWE@135623|Vibrionales 135623|Vibrionales H Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme - - 2.1.1.107 ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R03194 RC00003,RC00871 ko00000,ko00001,ko00002,ko01000 - - - TP_methylase k141_14932_1 1405.DJ92_4679 4.42e-89 269.0 COG2801@1|root,COG2801@2|Bacteria,1TQEG@1239|Firmicutes,4IPM1@91061|Bacilli,1ZRCB@1386|Bacillus 91061|Bacilli L DDE domain - - - - - - - - - - - - HTH_21,rve k141_9163_2 1279017.AQYJ01000028_gene2070 4.19e-39 135.0 COG0848@1|root,COG0848@2|Bacteria,1RHI8@1224|Proteobacteria,1S6FK@1236|Gammaproteobacteria,467HF@72275|Alteromonadaceae 1236|Gammaproteobacteria U COG0848 Biopolymer transport protein - - - - - - - - - - - - ExbD k141_24545_1 218284.CCDN010000002_gene2575 1e-74 236.0 2DBIQ@1|root,2Z9GR@2|Bacteria,1USK2@1239|Firmicutes,4HEDG@91061|Bacilli,1ZRBI@1386|Bacillus 91061|Bacilli S Spore germination B3/ GerAC like, C-terminal - - - ko:K06308 - - - - ko00000 - - - Spore_GerAC k141_32720_1 218284.CCDN010000007_gene3933 1.06e-61 194.0 2CWP1@1|root,32T03@2|Bacteria,1VAD2@1239|Firmicutes,4HKGQ@91061|Bacilli,1ZH2J@1386|Bacillus 91061|Bacilli S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA gerQ GO:0005575,GO:0005618,GO:0005623,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0018149,GO:0018153,GO:0018193,GO:0018199,GO:0018205,GO:0018262,GO:0019538,GO:0030312,GO:0031160,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0071704,GO:0071944,GO:1901564 - ko:K06305 - - - - ko00000 - - - Spore_GerQ k141_30280_1 1453501.JELR01000001_gene2613 2.1e-141 414.0 COG3067@1|root,COG3067@2|Bacteria,1MV0F@1224|Proteobacteria,1RPE3@1236|Gammaproteobacteria,464PD@72275|Alteromonadaceae 1236|Gammaproteobacteria P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons nhaB GO:0003674,GO:0005215,GO:0005451,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0006873,GO:0006885,GO:0008150,GO:0008324,GO:0009987,GO:0010035,GO:0010038,GO:0010226,GO:0015075,GO:0015077,GO:0015078,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015491,GO:0015672,GO:0016020,GO:0019725,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030004,GO:0030641,GO:0034220,GO:0035725,GO:0042221,GO:0042592,GO:0044464,GO:0045851,GO:0046873,GO:0048878,GO:0050801,GO:0050896,GO:0051179,GO:0051234,GO:0051452,GO:0051453,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0098771,GO:0099516,GO:1902600 - ko:K03314 - - - - ko00000,ko02000 2.A.34.1 - iECP_1309.ECP_1229,iLF82_1304.LF82_1485,iNRG857_1313.NRG857_06055,iUTI89_1310.UTI89_C1372 NhaB k141_9164_1 1294265.JCM21738_3319 8.29e-93 274.0 COG0517@1|root,COG0517@2|Bacteria,1TRZD@1239|Firmicutes,4HC4C@91061|Bacilli,1ZB0P@1386|Bacillus 91061|Bacilli K CBS domain ccpN GO:0006355,GO:0007154,GO:0007584,GO:0008150,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0042221,GO:0045013,GO:0045892,GO:0045934,GO:0045990,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0061984,GO:0061985,GO:0065007,GO:0070887,GO:0071496,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - - - - - - - - - - CBS,HTH_11 k141_4290_1 1031711.RSPO_c02425 7.51e-62 201.0 COG2133@1|root,COG2133@2|Bacteria,1MVK5@1224|Proteobacteria,2VIRC@28216|Betaproteobacteria,1K4ET@119060|Burkholderiaceae 28216|Betaproteobacteria G sorbosone dehydrogenase - - - - - - - - - - - - GSDH,SGL k141_4290_2 667632.KB890167_gene1474 2.38e-08 54.7 COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,2VGZ9@28216|Betaproteobacteria,1K28Y@119060|Burkholderiaceae 28216|Betaproteobacteria J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS proS - 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_2b,tRNA_edit k141_34048_1 218284.CCDN010000001_gene959 1.64e-43 150.0 2E6BB@1|root,330Z5@2|Bacteria,1VF3M@1239|Firmicutes,4HH7J@91061|Bacilli,1ZEMQ@1386|Bacillus 91061|Bacilli S stage III sporulation protein AG spoIIIAG - - ko:K06396 - - - - ko00000 - - - - k141_34048_2 218284.CCDN010000001_gene960 2.17e-87 261.0 29WYG@1|root,30IKQ@2|Bacteria,1V4Y2@1239|Firmicutes,4HI5K@91061|Bacilli,1ZHEH@1386|Bacillus 91061|Bacilli S SpoIIIAH-like protein spoIIIAH - - ko:K06397 - - - - ko00000 1.A.34.1.1 - - SpoIIIAH k141_34048_3 796606.BMMGA3_11430 1.28e-17 80.1 COG0511@1|root,COG0511@2|Bacteria,1VAB7@1239|Firmicutes,4HKCS@91061|Bacilli,1ZGFF@1386|Bacillus 91061|Bacilli I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA accB - - ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742 RC00040,RC00367 ko00000,ko00001,ko00002 - - - Biotin_lipoyl k141_7807_2 745411.B3C1_03025 0.000129 43.9 COG0429@1|root,COG0429@2|Bacteria,1MWV1@1224|Proteobacteria,1RN39@1236|Gammaproteobacteria,1J5UY@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S hydrolase of the alpha beta-hydrolase fold yheT GO:0003674,GO:0003824,GO:0006629,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0044237,GO:0044238,GO:0044255,GO:0050526,GO:0052689,GO:0071704 - ko:K07019 - - - - ko00000 - - - Abhydrolase_1 k141_14058_2 218284.CCDN010000005_gene3457 3.82e-33 115.0 2EG47@1|root,339W6@2|Bacteria,1VMG4@1239|Firmicutes,4HRAK@91061|Bacilli,1ZK0D@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_27905_1 218284.CCDN010000005_gene3426 2e-113 335.0 COG1252@1|root,COG1252@2|Bacteria,1TR6X@1239|Firmicutes,4HA14@91061|Bacilli,1ZAV9@1386|Bacillus 91061|Bacilli C NADH dehydrogenase yumB GO:0003674,GO:0003824,GO:0003955,GO:0006091,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0019646,GO:0022900,GO:0022904,GO:0044237,GO:0045333,GO:0055114 1.6.99.3 ko:K03885 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - iYO844.BSU32100 Pyr_redox_2 k141_35294_1 1122135.KB893166_gene3080 2.45e-86 264.0 COG1129@1|root,COG1129@2|Bacteria,1MVNR@1224|Proteobacteria,2TTCM@28211|Alphaproteobacteria 28211|Alphaproteobacteria G ABC transporter - - - - - - - - - - - - ABC_tran k141_24546_1 203122.Sde_0007 2.02e-43 145.0 COG3296@1|root,COG3296@2|Bacteria,1RET3@1224|Proteobacteria,1S4H0@1236|Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria - - - ko:K09940 - - - - ko00000 - - - DUF4870 k141_9165_1 1453501.JELR01000002_gene681 9.66e-77 242.0 COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,1RQR7@1236|Gammaproteobacteria,4668G@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria ycbB GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0006508,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0008236,GO:0008238,GO:0009273,GO:0009987,GO:0016740,GO:0016746,GO:0016755,GO:0016787,GO:0016807,GO:0017171,GO:0019538,GO:0033554,GO:0042546,GO:0043164,GO:0043170,GO:0044036,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0050896,GO:0051716,GO:0070004,GO:0070008,GO:0070011,GO:0071554,GO:0071704,GO:0071840,GO:0071972,GO:0140096,GO:1901564 - ko:K21470 - - - - ko00000,ko01002,ko01011 - - - PG_binding_1,YkuD k141_19787_1 1177179.A11A3_14365 4.36e-48 169.0 COG2244@1|root,COG2244@2|Bacteria,1MWKV@1224|Proteobacteria,1S4AZ@1236|Gammaproteobacteria,1XQ6A@135619|Oceanospirillales 135619|Oceanospirillales S Polysaccharide biosynthesis protein - - - - - - - - - - - - Polysacc_synt,Polysacc_synt_C k141_3022_1 218284.CCDN010000002_gene2878 9.33e-101 305.0 COG2268@1|root,COG2268@2|Bacteria,1TQDT@1239|Firmicutes,4HA0C@91061|Bacilli,1ZBTE@1386|Bacillus 91061|Bacilli S protein conserved in bacteria yuaG - - ko:K07192 ko04910,map04910 - - - ko00000,ko00001,ko03036,ko04131,ko04147 - - - Band_7,Flot k141_20856_1 491952.Mar181_2522 1.5e-256 715.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,1XHIY@135619|Oceanospirillales 135619|Oceanospirillales C Belongs to the aldehyde dehydrogenase family - - 1.2.1.39,1.2.1.99 ko:K00146,ko:K09472 ko00330,ko00360,ko00643,ko01100,ko01120,map00330,map00360,map00643,map01100,map01120 M00136 R02536,R07417,R07418 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_32721_1 218284.CCDN010000001_gene1779 7.61e-105 315.0 COG3852@1|root,COG3852@2|Bacteria,1TRH0@1239|Firmicutes,4HD4A@91061|Bacilli,1ZDWU@1386|Bacillus 91061|Bacilli T COG0642 Signal transduction histidine kinase kinC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 ko:K07698 ko02020,map02020 M00485 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS,PAS_3,PAS_9 k141_9166_1 218284.CCDN010000001_gene609 2.69e-129 392.0 COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,4HB85@91061|Bacilli,1ZAS4@1386|Bacillus 91061|Bacilli J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner valS GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 k141_10380_1 1453501.JELR01000001_gene1950 1.87e-81 257.0 COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,1RMU9@1236|Gammaproteobacteria,46456@72275|Alteromonadaceae 1236|Gammaproteobacteria U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components ffh GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006605,GO:0006612,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046907,GO:0048500,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1990904 3.6.5.4 ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko01000,ko02044 3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9 - - SRP54,SRP54_N,SRP_SPB k141_10380_4 1042377.AFPJ01000037_gene2888 7.61e-153 432.0 COG0336@1|root,COG0336@2|Bacteria,1MUN1@1224|Proteobacteria,1RMWC@1236|Gammaproteobacteria,464K1@72275|Alteromonadaceae 1236|Gammaproteobacteria J Belongs to the RNA methyltransferase TrmD family trmD GO:0000287,GO:0001510,GO:0002939,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050518,GO:0052906,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 ko:K00554 - - R00597 RC00003,RC00334 ko00000,ko01000,ko03016 - - - tRNA_m1G_MT k141_10380_6 1122194.AUHU01000005_gene996 6.48e-130 379.0 COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,1RPI8@1236|Gammaproteobacteria,464UI@72275|Alteromonadaceae 1236|Gammaproteobacteria D COG4974 Site-specific recombinase XerD xerD GO:0000150,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008907,GO:0009009,GO:0009037,GO:0009314,GO:0009628,GO:0009987,GO:0015074,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0071139,GO:0071704,GO:0090304,GO:0140097,GO:1901360 - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase k141_10380_7 1279017.AQYJ01000026_gene321 1.51e-133 383.0 COG1651@1|root,COG1651@2|Bacteria,1RD39@1224|Proteobacteria,1S3U8@1236|Gammaproteobacteria,466TU@72275|Alteromonadaceae 1236|Gammaproteobacteria M Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process dsbC - 5.3.4.1 ko:K03981 - - - - ko00000,ko01000,ko02044,ko03110 3.A.7.11.1 - - DsbC_N,Thioredoxin_2 k141_862_2 665959.HMPREF1013_05732 1.25e-108 316.0 COG0311@1|root,COG0311@2|Bacteria,1V3I6@1239|Firmicutes,4HFSZ@91061|Bacilli,1ZD5C@1386|Bacillus 91061|Bacilli H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS pdxT GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 ko:K08681 ko00750,map00750 - R07456 RC00010,RC01783,RC03043 ko00000,ko00001,ko01000 - - - SNO k141_24547_1 218284.CCDN010000007_gene3860 8.25e-145 446.0 COG1674@1|root,COG1674@2|Bacteria,1TRA4@1239|Firmicutes,4H9QM@91061|Bacilli,1ZDSN@1386|Bacillus 91061|Bacilli D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins essC - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FHA,FtsK_SpoIIIE,FtsK_SpoIIIE_N k141_30281_1 218284.CCDN010000001_gene659 1.01e-66 218.0 COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,4HAB7@91061|Bacilli,1ZDHC@1386|Bacillus 91061|Bacilli S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid spoVB - - ko:K06409 - - - - ko00000,ko02000 2.A.66.2.14 - - Polysacc_synt,Polysacc_synt_C k141_1824_2 999141.GME_04667 4.88e-28 102.0 COG1551@1|root,COG1551@2|Bacteria,1N6PG@1224|Proteobacteria,1SCB4@1236|Gammaproteobacteria,1XKZ6@135619|Oceanospirillales 135619|Oceanospirillales T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding csrA - - ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 - - - ko00000,ko00001,ko03019 - - - CsrA k141_34049_1 994573.T472_0218580 4.06e-56 191.0 COG0591@1|root,COG0591@2|Bacteria,1TPVE@1239|Firmicutes,248NQ@186801|Clostridia,36FNJ@31979|Clostridiaceae 186801|Clostridia E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - ko:K03307 - - - - ko00000 2.A.21 - - SSF k141_12814_1 1042377.AFPJ01000004_gene387 4.25e-90 285.0 COG4206@1|root,COG4206@2|Bacteria,1QUGQ@1224|Proteobacteria,1T241@1236|Gammaproteobacteria,464Q2@72275|Alteromonadaceae 1236|Gammaproteobacteria H TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_18752_1 1453501.JELR01000001_gene2592 3.27e-62 199.0 COG3932@1|root,COG3932@2|Bacteria,1N0FN@1224|Proteobacteria,1S4SJ@1236|Gammaproteobacteria,467N5@72275|Alteromonadaceae 1236|Gammaproteobacteria S ABC-type transport system, permease components - - - - - - - - - - - - ExoD k141_18752_2 1453501.JELR01000006_gene2 2.46e-82 252.0 COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,1RMSS@1236|Gammaproteobacteria,4651Y@72275|Alteromonadaceae 1236|Gammaproteobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_int_SAM_4,Phage_integrase k141_11582_1 574966.KB898649_gene249 8.15e-118 350.0 COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,1RMW3@1236|Gammaproteobacteria,1XHFK@135619|Oceanospirillales 135619|Oceanospirillales G Belongs to the pyruvate kinase family - - 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - PK,PK_C k141_9167_1 218284.CCDN010000001_gene1118 2.82e-100 301.0 COG0287@1|root,COG0287@2|Bacteria,1TPXG@1239|Firmicutes,4HBI4@91061|Bacilli,1ZBVZ@1386|Bacillus 91061|Bacilli E prephenate dehydrogenase tyrA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.3.1.12 ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00025 R01728 RC00125 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU22610 ACT,PDH k141_18765_5 1279017.AQYJ01000019_gene1500 2.11e-304 840.0 COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,1RMXX@1236|Gammaproteobacteria,4663F@72275|Alteromonadaceae 1236|Gammaproteobacteria S Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane murJ GO:0000270,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0006869,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0010876,GO:0015647,GO:0015648,GO:0015835,GO:0015836,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0030203,GO:0031224,GO:0031226,GO:0033036,GO:0034203,GO:0034204,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0046836,GO:0051179,GO:0051234,GO:0055085,GO:0061024,GO:0065007,GO:0065008,GO:0070589,GO:0071554,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0071944,GO:0097035,GO:1901135,GO:1901137,GO:1901264,GO:1901505,GO:1901564,GO:1901566,GO:1901576 - ko:K03980 - - - - ko00000,ko01011,ko02000 2.A.66.4 - iECO103_1326.ECO103_1114 MVIN k141_18765_6 1279017.AQYJ01000019_gene1501 9.68e-192 538.0 COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,1RN44@1236|Gammaproteobacteria,464EI@72275|Alteromonadaceae 1236|Gammaproteobacteria H Belongs to the ribF family ribF GO:0003674,GO:0003824,GO:0003919,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008531,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0044237,GO:0070566 2.7.1.26,2.7.7.2 ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - iETEC_1333.ETEC_0025,iJN746.PP_0602 FAD_syn,Flavokinase k141_18765_7 1279017.AQYJ01000019_gene1502 0.0 1709.0 COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,1RMTF@1236|Gammaproteobacteria,46514@72275|Alteromonadaceae 1236|Gammaproteobacteria J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iG2583_1286.G2583_0027,iPC815.YPO0475 Anticodon_1,tRNA-synt_1,zf-FPG_IleRS k141_14956_1 87626.PTD2_04506 9.87e-06 51.6 COG1595@1|root,COG1595@2|Bacteria,1N38X@1224|Proteobacteria,1SASQ@1236|Gammaproteobacteria,2Q35E@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4,Sigma70_r4_2 k141_24576_2 1307436.PBF_04355 3.45e-168 476.0 COG4653@1|root,COG4653@2|Bacteria,1UZMZ@1239|Firmicutes,4HBKI@91061|Bacilli,1ZEHH@1386|Bacillus 91061|Bacilli S Phage capsid family - - - - - - - - - - - - Phage_capsid k141_23504_1 665959.HMPREF1013_01964 8.03e-96 287.0 COG0204@1|root,COG0204@2|Bacteria,1UMJA@1239|Firmicutes,4HD2E@91061|Bacilli,1ZEYG@1386|Bacillus 91061|Bacilli I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family ypkP - 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase k141_11610_1 935836.JAEL01000007_gene2898 2.23e-73 227.0 COG1414@1|root,COG1414@2|Bacteria,1TRMW@1239|Firmicutes,4HCSI@91061|Bacilli,1ZDR0@1386|Bacillus 91061|Bacilli K Transcriptional regulator kipR - - ko:K13641 - - - - ko00000,ko03000 - - - HTH_IclR,IclR k141_12827_1 1131730.BAVI_12389 5.72e-07 51.2 2DBAR@1|root,2Z849@2|Bacteria,1V2D9@1239|Firmicutes,4HDYQ@91061|Bacilli,1ZCAR@1386|Bacillus 91061|Bacilli S Spore germination B3/ GerAC like, C-terminal - - - - - - - - - - - - Spore_GerAC k141_12827_2 1294265.JCM21738_1298 6.64e-107 319.0 COG0531@1|root,COG0531@2|Bacteria,1V3R2@1239|Firmicutes,4HICB@91061|Bacilli,1ZF88@1386|Bacillus 91061|Bacilli E Spore germination protein - - - - - - - - - - - - Spore_permease k141_9192_1 218284.CCDN010000001_gene1916 2.37e-137 391.0 COG1338@1|root,COG1338@2|Bacteria,1TPIE@1239|Firmicutes,4HA79@91061|Bacilli,1ZCWT@1386|Bacillus 91061|Bacilli N Plays a role in the flagellum-specific transport system fliP - - ko:K02419 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - FliP k141_36257_1 1116375.VEJY3_24251 0.0 1056.0 COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,1RN2V@1236|Gammaproteobacteria,1XSD5@135623|Vibrionales 135623|Vibrionales P Arylsulfatase - - 3.1.6.1 ko:K01130 ko00140,ko00600,map00140,map00600 - R03980,R04856 RC00128,RC00231 ko00000,ko00001,ko01000 - - - Sulfatase,Sulfatase_C k141_10390_1 218284.CCDN010000002_gene2245 6.26e-81 253.0 COG0441@1|root,COG0441@2|Bacteria,1UHT4@1239|Firmicutes,4IS8T@91061|Bacilli,1ZS31@1386|Bacillus 91061|Bacilli J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) proS - 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,ProRS-C_1,tRNA-synt_2b k141_20876_2 1122137.AQXF01000007_gene3600 7.74e-21 93.2 COG0644@1|root,COG0644@2|Bacteria,1R41S@1224|Proteobacteria,2TW03@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Tryptophan halogenase - - 1.14.19.9 ko:K14266 ko00404,ko01130,map00404,map01130 M00789,M00790 R09570 RC00949 ko00000,ko00001,ko00002,ko01000 - - - Trp_halogenase k141_18767_1 218284.CCDN010000002_gene2141 9.02e-88 269.0 COG0160@1|root,COG0160@2|Bacteria,1VS6F@1239|Firmicutes,4H9M7@91061|Bacilli,1ZAZ9@1386|Bacillus 91061|Bacilli E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family gabT - 2.6.1.19 ko:K00823 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 M00027 R00908,R01648 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 k141_27910_1 1220589.CD32_09805 6.84e-83 254.0 COG0122@1|root,COG0122@2|Bacteria,1TQAF@1239|Firmicutes,4HBYM@91061|Bacilli,3IX9P@400634|Lysinibacillus 91061|Bacilli L DNA-3-methyladenine alkA - 3.2.2.21 ko:K01247,ko:K13529 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03000,ko03400 - - - AlkA_N,HhH-GPD,OGG_N k141_29265_1 246196.MSMEI_5442 1.85e-72 237.0 COG0028@1|root,COG0028@2|Bacteria,2GIX3@201174|Actinobacteria,2376B@1762|Mycobacteriaceae 201174|Actinobacteria EH Thiamine pyrophosphate enzyme, central domain - - - - - - - - - - - - Rieske,TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N k141_11611_1 218284.CCDN010000002_gene2010 1.09e-115 337.0 COG0078@1|root,COG0078@2|Bacteria,1TPF2@1239|Firmicutes,4H9X8@91061|Bacilli,1ZC5E@1386|Bacillus 91061|Bacilli E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline argF GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 M00029,M00844 R01398 RC00096 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N k141_7113_2 1217656.F964_00513 1.53e-14 84.7 COG4643@1|root,COG4643@2|Bacteria 2|Bacteria P DNA integration traC - - - - - - - - - - - DUF3987,DUF3991,Toprim_2,Toprim_3 k141_5829_2 760192.Halhy_4269 2.66e-139 416.0 COG0076@1|root,COG0076@2|Bacteria,4NFUP@976|Bacteroidetes,1IVP1@117747|Sphingobacteriia 976|Bacteroidetes E COGs COG0076 Glutamate decarboxylase and related PLP-dependent protein - - - - - - - - - - - - Pyridoxal_deC k141_37670_2 218284.CCDN010000001_gene1049 3.04e-185 526.0 COG0697@1|root,COG0697@2|Bacteria,1TP7K@1239|Firmicutes,4HBWN@91061|Bacilli,1ZB54@1386|Bacillus 91061|Bacilli EG Stage V sporulation protein AF spoVAF - - ko:K06408 - - - - ko00000 - - - GerA k141_16400_1 78245.Xaut_2415 2.79e-30 115.0 COG1129@1|root,COG1129@2|Bacteria,1MVNR@1224|Proteobacteria,2TTCM@28211|Alphaproteobacteria 28211|Alphaproteobacteria G ABC transporter - - 3.6.3.17 ko:K02056,ko:K10554 ko02010,map02010 M00218,M00221 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.2,3.A.1.2.7 - - ABC_tran k141_16400_2 388399.SSE37_01270 2.53e-36 126.0 2FK21@1|root,34BQ8@2|Bacteria,1P074@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_16400_3 388399.SSE37_01275 3.6e-14 70.1 2F0GU@1|root,33TJP@2|Bacteria,1NSJ5@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_21028_1 1294265.JCM21738_5077 4.05e-113 327.0 COG1179@1|root,COG1179@2|Bacteria,1TQ7A@1239|Firmicutes,4H9KZ@91061|Bacilli,1ZBGG@1386|Bacillus 91061|Bacilli H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 yrvM GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016829,GO:0016835,GO:0016836,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0061503,GO:0061504,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 - ko:K22132 - - - - ko00000,ko03016 - - - ThiF k141_35555_1 218284.CCDN010000001_gene728 3.84e-121 357.0 COG0860@1|root,COG0860@2|Bacteria,1TSFS@1239|Firmicutes,4HACZ@91061|Bacilli,1ZAV0@1386|Bacillus 91061|Bacilli M stage II sporulation protein P spoIIP - - ko:K06385 - - - - ko00000 - - - SpoIIP k141_22490_1 218284.CCDN010000001_gene1174 2.59e-159 450.0 COG2897@1|root,COG2897@2|Bacteria,1TRYA@1239|Firmicutes,4HAQA@91061|Bacilli,1ZANF@1386|Bacillus 91061|Bacilli P sulfurtransferase sseA - 2.8.1.1,2.8.1.2 ko:K01011 ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122 - R01931,R03105,R03106 RC00214 ko00000,ko00001,ko01000 - - - Rhodanese k141_5830_1 218284.CCDN010000005_gene3181 2.97e-225 626.0 COG4473@1|root,COG4473@2|Bacteria,1V1VG@1239|Firmicutes,4HG1K@91061|Bacilli,1ZBQG@1386|Bacillus 91061|Bacilli U ABC transporter ecsB - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - EcsB k141_22491_1 1042377.AFPJ01000054_gene1693 3.85e-58 194.0 COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,1RMB9@1236|Gammaproteobacteria,464ZX@72275|Alteromonadaceae 1236|Gammaproteobacteria O ATPase with chaperone activity comM GO:0003674,GO:0003824,GO:0004176,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0042623,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - ko:K07391 - - - - ko00000 - - - ChlI,Mg_chelatase,Mg_chelatase_C k141_22491_2 760117.JN27_08140 4.59e-29 109.0 COG1670@1|root,COG1670@2|Bacteria,1RCX2@1224|Proteobacteria,2VQS6@28216|Betaproteobacteria,477HB@75682|Oxalobacteraceae 28216|Betaproteobacteria J Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_3 k141_30420_1 1453501.JELR01000002_gene79 2.28e-76 251.0 COG3127@1|root,COG3127@2|Bacteria,1MU9R@1224|Proteobacteria,1RM8Y@1236|Gammaproteobacteria,4654Y@72275|Alteromonadaceae 1236|Gammaproteobacteria Q ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component ybbP GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX k141_30420_2 1279017.AQYJ01000021_gene2782 3.36e-130 374.0 COG4181@1|root,COG4181@2|Bacteria,1MXG9@1224|Proteobacteria,1RMG1@1236|Gammaproteobacteria,466GJ@72275|Alteromonadaceae 1236|Gammaproteobacteria Q ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component ybbA GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_30420_3 1279017.AQYJ01000021_gene2783 2.64e-106 312.0 COG2755@1|root,COG2755@2|Bacteria,1RCXZ@1224|Proteobacteria,1S3QU@1236|Gammaproteobacteria,466ZZ@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG2755 Lysophospholipase L1 and related esterases tesA GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016289,GO:0016290,GO:0016298,GO:0016787,GO:0016788,GO:0016790,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0047617,GO:0052689,GO:0071704,GO:0140096,GO:1901564 3.1.1.5 ko:K10804 ko01040,map01040 - - - ko00000,ko00001,ko01000,ko01004 - - iECED1_1282.ECED1_0521,iLF82_1304.LF82_2242,iNRG857_1313.NRG857_02365 Lipase_GDSL_2 k141_30420_6 1453501.JELR01000002_gene74 7.11e-292 804.0 COG0591@1|root,COG0591@2|Bacteria,1MUBI@1224|Proteobacteria,1RMXU@1236|Gammaproteobacteria,464J5@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family putP - - ko:K11928 - - - - ko00000,ko02000 2.A.21.2 - - SSF k141_30420_7 1453501.JELR01000002_gene73 3.1e-99 290.0 COG2110@1|root,COG2110@2|Bacteria,1RCWP@1224|Proteobacteria,1S3WJ@1236|Gammaproteobacteria,468H4@72275|Alteromonadaceae 1236|Gammaproteobacteria S Appr-1'-p processing enzyme ymdB GO:0003674,GO:0003824,GO:0004857,GO:0005488,GO:0005515,GO:0008150,GO:0008428,GO:0009892,GO:0010605,GO:0016787,GO:0019213,GO:0019219,GO:0019222,GO:0019899,GO:0030234,GO:0031323,GO:0031324,GO:0032069,GO:0032074,GO:0043086,GO:0043900,GO:0044092,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060698,GO:0060699,GO:0060700,GO:0060701,GO:0060702,GO:0061463,GO:0065007,GO:0065009,GO:0080090,GO:0098772,GO:1900190,GO:1900231 - - - - - - - - - - Macro k141_30420_8 1279017.AQYJ01000021_gene2789 1.05e-89 265.0 COG4539@1|root,COG4539@2|Bacteria,1N1G8@1224|Proteobacteria,1S9FD@1236|Gammaproteobacteria,466RD@72275|Alteromonadaceae 1236|Gammaproteobacteria S membrane - - - - - - - - - - - - DUF962 k141_30420_10 1453501.JELR01000002_gene67 8.76e-261 716.0 COG0686@1|root,COG0686@2|Bacteria,1QTX1@1224|Proteobacteria,1T1JB@1236|Gammaproteobacteria,465EE@72275|Alteromonadaceae 1236|Gammaproteobacteria C Belongs to the AlaDH PNT family ald - 1.4.1.1 ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 - R00396 RC00008 ko00000,ko00001,ko01000 - - - AlaDh_PNT_C,AlaDh_PNT_N k141_30420_11 633149.Bresu_2541 3.83e-13 68.9 2EIJE@1|root,33CAQ@2|Bacteria,1NH29@1224|Proteobacteria,2UJZ4@28211|Alphaproteobacteria,2KHHA@204458|Caulobacterales 204458|Caulobacterales S Psort location CytoplasmicMembrane, score - - - - - - - - - - - - - k141_30420_12 1453501.JELR01000002_gene66 1.48e-100 298.0 COG1385@1|root,COG1385@2|Bacteria,1MZBG@1224|Proteobacteria,1S0HM@1236|Gammaproteobacteria,464CI@72275|Alteromonadaceae 1236|Gammaproteobacteria J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit - - - - - - - - - - - - Methyltrans_RNA k141_1113_1 1294265.JCM21738_388 1.33e-89 272.0 COG0612@1|root,COG0612@2|Bacteria,1TPN6@1239|Firmicutes,4H9P5@91061|Bacilli,1ZCAJ@1386|Bacillus 91061|Bacilli S Peptidase M16 albE - - - - - - - - - - - Peptidase_M16_C k141_37671_1 1321781.HMPREF1985_00635 9.87e-36 133.0 COG0164@1|root,COG0164@2|Bacteria,1V1D6@1239|Firmicutes,4H3YJ@909932|Negativicutes 909932|Negativicutes L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhB - 3.1.26.4 ko:K03470 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_HII k141_7116_1 218284.CCDN010000001_gene967 2.5e-91 281.0 COG1570@1|root,COG1570@2|Bacteria,1TP4E@1239|Firmicutes,4HAN2@91061|Bacilli,1ZB5Q@1386|Bacillus 91061|Bacilli L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseA - 3.1.11.6 ko:K03601 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_L,tRNA_anti_2 k141_26097_2 935836.JAEL01000043_gene4324 5.55e-74 234.0 COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,4H9Z5@91061|Bacilli,1ZBCS@1386|Bacillus 91061|Bacilli C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes bfmBC - 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyr_redox_2,Pyr_redox_dim k141_35556_1 1294265.JCM21738_2283 2.96e-169 492.0 COG2202@1|root,COG5002@1|root,COG2202@2|Bacteria,COG5002@2|Bacteria,1VUBP@1239|Firmicutes,4HUPW@91061|Bacilli,1ZS15@1386|Bacillus 91061|Bacilli T Histidine kinase kinA - 2.7.13.3 ko:K02491 ko02020,map02020 M00485 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - 5TM-5TMR_LYT,HATPase_c,HisKA,MASE3,MHYT,PAS,PAS_3,PAS_4,PAS_9 k141_20075_1 1453501.JELR01000001_gene2604 2.73e-124 370.0 COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,1SYC8@1236|Gammaproteobacteria,46AMB@72275|Alteromonadaceae 1236|Gammaproteobacteria P Sulfate permease family - - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - STAS,Sulfate_transp k141_15135_1 666686.B1NLA3E_18360 4.87e-111 331.0 COG0477@1|root,COG2814@2|Bacteria,1TQHD@1239|Firmicutes,4HBCZ@91061|Bacilli,1ZDDG@1386|Bacillus 91061|Bacilli EGP COG0477 Permeases of the major facilitator superfamily - - - - - - - - - - - - MFS_1,Sugar_tr k141_4457_1 1116375.VEJY3_16711 0.0 866.0 COG4303@1|root,COG4303@2|Bacteria,1MUR4@1224|Proteobacteria,1RPN8@1236|Gammaproteobacteria,1XVRK@135623|Vibrionales 135623|Vibrionales E Ethanolamine ammonia lyase large subunit (EutB) - - 4.3.1.7 ko:K03735 ko00564,ko01100,map00564,map01100 - R00749 RC00370 ko00000,ko00001,ko01000 - - - EutB k141_3271_1 218284.CCDN010000002_gene2021 2.83e-99 291.0 COG0526@1|root,COG0526@2|Bacteria,1V2DU@1239|Firmicutes,4HGQZ@91061|Bacilli,1ZG9D@1386|Bacillus 91061|Bacilli CO Thioredoxin - - - - - - - - - - - - Thioredoxin_9 k141_7117_1 379066.GAU_0606 6.45e-27 106.0 COG0601@1|root,COG0601@2|Bacteria,1ZSXJ@142182|Gemmatimonadetes 142182|Gemmatimonadetes U Binding-protein-dependent transport system inner membrane component - - - ko:K02033 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 k141_7117_2 331869.BAL199_13063 1.99e-25 103.0 COG1173@1|root,COG1173@2|Bacteria,1MUG0@1224|Proteobacteria,2VETJ@28211|Alphaproteobacteria,4BT9W@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria EP N-terminal TM domain of oligopeptide transport permease C - - - ko:K02034,ko:K12370 ko02010,ko02024,map02010,map02024 M00239,M00324 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1,OppC_N k141_28093_1 1294265.JCM21738_4477 1.15e-86 261.0 2BJ57@1|root,32DEE@2|Bacteria,1V93H@1239|Firmicutes,4HN71@91061|Bacilli,1ZH00@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF1510) yrrS - - - - - - - - - - - DUF1510 k141_2020_1 935836.JAEL01000036_gene2994 1.87e-09 53.9 2E4N3@1|root,32ZGZ@2|Bacteria,1VJY0@1239|Firmicutes,4HPM3@91061|Bacilli,1ZJCF@1386|Bacillus 91061|Bacilli S Family of unknown function (DUF5370) ybxH - - - - - - - - - - - DUF5370 k141_2020_2 935836.JAEL01000022_gene1621 6.94e-121 356.0 COG1301@1|root,COG1301@2|Bacteria,1TPME@1239|Firmicutes,4H9T7@91061|Bacilli,1ZCSU@1386|Bacillus 91061|Bacilli C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - - - - - - - - - - SDF k141_5831_1 218284.CCDN010000001_gene1387 8.19e-176 509.0 COG2905@1|root,COG2905@2|Bacteria,1TQFI@1239|Firmicutes,4HDTM@91061|Bacilli,1ZQQC@1386|Bacillus 91061|Bacilli T Putative nucleotidyltransferase substrate binding domain - - - ko:K07182 - - - - ko00000 - - - CBS,DUF294,DUF294_C,cNMP_binding k141_21030_1 1040982.AXAL01000006_gene297 1.15e-09 65.9 COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,43JWG@69277|Phyllobacteriaceae 28211|Alphaproteobacteria T Adenylyl- / guanylyl cyclase, catalytic domain - - - - - - - - - - - - Guanylate_cyc,TPR_16,TPR_2,TPR_8 k141_37672_1 1453501.JELR01000002_gene850 7.28e-114 339.0 COG5434@1|root,COG5434@2|Bacteria,1MXP8@1224|Proteobacteria,1RRJZ@1236|Gammaproteobacteria,4644J@72275|Alteromonadaceae 1236|Gammaproteobacteria G Belongs to the glycosyl hydrolase 28 family - - - - - - - - - - - - Glyco_hydro_28,Pectate_lyase_3 k141_35558_1 1453501.JELR01000002_gene350 6.27e-88 278.0 COG0457@1|root,COG0457@2|Bacteria,1MXSS@1224|Proteobacteria,1S157@1236|Gammaproteobacteria,46CPY@72275|Alteromonadaceae 1236|Gammaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16 k141_9475_1 1294265.JCM21738_215 1.13e-50 162.0 COG1963@1|root,COG1963@2|Bacteria,1VAVC@1239|Firmicutes,4HHA6@91061|Bacilli,1ZFKA@1386|Bacillus 91061|Bacilli S protein conserved in bacteria - - - ko:K09775 - - - - ko00000 - - - DUF212 k141_9475_2 1307436.PBF_24538 1.31e-17 74.3 28USI@1|root,2ZGWR@2|Bacteria,1W1QB@1239|Firmicutes,4I101@91061|Bacilli,1ZJZW@1386|Bacillus 91061|Bacilli - - - - - ko:K06429 - - - - ko00000 - - - - k141_9475_3 1294265.JCM21738_213 1.68e-24 99.8 COG0258@1|root,COG0258@2|Bacteria,1TQ05@1239|Firmicutes,4H9UW@91061|Bacilli,1ZB2Z@1386|Bacillus 91061|Bacilli L 5'3' exonuclease ypcP - - - - - - - - - - - 5_3_exonuc,5_3_exonuc_N k141_22494_1 1121468.AUBR01000065_gene965 1.86e-97 304.0 COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,247VN@186801|Clostridia,42EYD@68295|Thermoanaerobacterales 186801|Clostridia J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome fusA - - ko:K02355 - - - - ko00000,ko03012,ko03029 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 k141_17466_2 1279017.AQYJ01000026_gene37 1.59e-114 328.0 COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,1S222@1236|Gammaproteobacteria,466DM@72275|Alteromonadaceae 1236|Gammaproteobacteria O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides ppiB GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 ko:K03768 - - - - ko00000,ko01000,ko03110 - - - Pro_isomerase k141_17466_3 1453501.JELR01000001_gene2574 2.73e-128 369.0 COG2908@1|root,COG2908@2|Bacteria,1N3U7@1224|Proteobacteria,1RP1X@1236|Gammaproteobacteria,466F4@72275|Alteromonadaceae 1236|Gammaproteobacteria S Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxH GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0019897,GO:0019898,GO:0030145,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.6.1.54 ko:K03269 ko00540,ko01100,map00540,map01100 M00060 R04549 RC00002 ko00000,ko00001,ko00002,ko01000,ko01005 - - iE2348C_1286.E2348C_0457 Metallophos,Metallophos_2 k141_17466_4 1279017.AQYJ01000026_gene42 4.19e-172 492.0 COG1748@1|root,COG1748@2|Bacteria,1N22C@1224|Proteobacteria,1RXXV@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Saccharopine dehydrogenase - - - - - - - - - - - - Sacchrp_dh_NADP k141_17466_5 331869.BAL199_19638 5.91e-33 121.0 COG0778@1|root,COG0778@2|Bacteria,1R9VX@1224|Proteobacteria,2U5B0@28211|Alphaproteobacteria 28211|Alphaproteobacteria C NADH dehydrogenase nad(P)h nitroreductase rutE - - ko:K09019 ko00240,ko01100,map00240,map01100 - R09289 RC00087 ko00000,ko00001,ko01000 - - - Nitroreductase k141_30421_1 218284.CCDN010000002_gene2395 1.19e-17 81.6 2DBJR@1|root,2Z9N7@2|Bacteria,1TRSN@1239|Firmicutes,4HCDI@91061|Bacilli,1ZN92@1386|Bacillus 91061|Bacilli S Spore germination B3/ GerAC like, C-terminal - - - - - - - - - - - - Spore_GerAC k141_30421_2 218284.CCDN010000002_gene2396 1.05e-57 193.0 COG0697@1|root,COG0697@2|Bacteria,1TP7K@1239|Firmicutes,4HAH1@91061|Bacilli,1ZBEF@1386|Bacillus 91061|Bacilli EG Spore germination protein - - - ko:K06295 - - - - ko00000 - - - GerA k141_1114_1 1279017.AQYJ01000024_gene945 1.54e-132 397.0 COG4264@1|root,COG4264@2|Bacteria,1MVUU@1224|Proteobacteria,1RPN4@1236|Gammaproteobacteria,4688G@72275|Alteromonadaceae 1236|Gammaproteobacteria Q IucA / IucC family iucC - 6.3.2.39 ko:K03895 ko00310,ko01120,map00310,map01120 - R10091 RC00064,RC00090 ko00000,ko00001,ko01000 - - - FhuF,IucA_IucC k141_7119_1 42565.FP66_00485 6.53e-69 215.0 COG0583@1|root,COG0583@2|Bacteria,1R43D@1224|Proteobacteria,1S33J@1236|Gammaproteobacteria,1XP04@135619|Oceanospirillales 135619|Oceanospirillales K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate k141_4460_1 665959.HMPREF1013_03693 1.64e-64 208.0 COG1984@1|root,COG1984@2|Bacteria,1TR6U@1239|Firmicutes,4HACC@91061|Bacilli,1ZCFE@1386|Bacillus 91061|Bacilli E Allophanate hydrolase subunit 2 kipA - - ko:K06350 - - - - ko00000 - - - CT_A_B k141_31582_1 218284.CCDN010000001_gene1418 9.01e-107 309.0 COG0693@1|root,COG0693@2|Bacteria,1V1CG@1239|Firmicutes,4HFRX@91061|Bacilli,1ZEFQ@1386|Bacillus 91061|Bacilli S DJ-1/PfpI family yraA - 3.5.1.124 ko:K05520 - - - - ko00000,ko01000,ko01002 - - - DJ-1_PfpI k141_31582_2 1196031.ALEG01000044_gene4438 1.91e-19 82.4 2EM3I@1|root,33ET1@2|Bacteria,1VI7I@1239|Firmicutes,4HRBY@91061|Bacilli,1ZI9V@1386|Bacillus 91061|Bacilli S Phage holin family Hol44, in holin superfamily V - - - - - - - - - - - - Phage_holin_5_2 k141_37673_1 218284.CCDN010000001_gene803 1.06e-52 178.0 COG0697@1|root,COG0697@2|Bacteria,1TP7K@1239|Firmicutes,4HBWN@91061|Bacilli,1ZAS9@1386|Bacillus 91061|Bacilli EG Bacillus/Clostridium GerA spore germination protein spoVAF - - ko:K06408 - - - - ko00000 - - - GerA k141_37673_2 218284.CCDN010000001_gene802 1.92e-13 69.3 28I64@1|root,2Z898@2|Bacteria,1TQX0@1239|Firmicutes,4HF76@91061|Bacilli,1ZEIB@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_3273_1 1453501.JELR01000002_gene950 2e-103 323.0 COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,1RM7J@1236|Gammaproteobacteria,464YC@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG5009 Membrane carboxypeptidase penicillin-binding protein mrcA GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0008955,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - PCB_OB,Transgly,Transpeptidase k141_10497_1 187272.Mlg_1940 3.98e-65 206.0 COG1225@1|root,COG1225@2|Bacteria,1R9YF@1224|Proteobacteria,1S37E@1236|Gammaproteobacteria,1WWWB@135613|Chromatiales 135613|Chromatiales O PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - - - - - - - - - - AhpC-TSA k141_29504_1 1453501.JELR01000001_gene1999 5.11e-66 210.0 COG1214@1|root,COG1214@2|Bacteria,1MXPH@1224|Proteobacteria,1RPYX@1236|Gammaproteobacteria,466QS@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG1214 Inactive homolog of metal-dependent proteases yeaZ GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 - ko:K14742 - - - - ko00000,ko03016 - - - Peptidase_M22 k141_11858_2 1401065.HMPREF2130_11430 8.93e-36 129.0 COG2409@1|root,COG2409@2|Bacteria,1NRRD@1224|Proteobacteria 1224|Proteobacteria S Drug exporters of the RND superfamily - - - - - - - - - - - - - k141_22527_1 292415.Tbd_1464 2.17e-135 397.0 COG2843@1|root,COG2843@2|Bacteria,1P1MG@1224|Proteobacteria,2VIGZ@28216|Betaproteobacteria,1KTA6@119069|Hydrogenophilales 119069|Hydrogenophilales M Bacterial capsule synthesis protein PGA_cap - - - ko:K07282 - - - - ko00000 - - - PGA_cap k141_24792_1 218284.CCDN010000001_gene1187 1.24e-117 352.0 COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,4HA2X@91061|Bacilli,1ZCFH@1386|Bacillus 91061|Bacilli F Belongs to the formate--tetrahydrofolate ligase family fhs GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.3 ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R00943 RC00026,RC00111 ko00000,ko00001,ko00002,ko01000 - - - FTHFS k141_4496_1 218284.CCDN010000001_gene782 2.65e-42 145.0 COG5521@1|root,COG5521@2|Bacteria,1V2MC@1239|Firmicutes,4HGIF@91061|Bacilli,1ZBMN@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF1189) yqgB - - - - - - - - - - - DUF1189 k141_5854_1 760192.Halhy_6021 9.4e-25 100.0 COG0697@1|root,COG0697@2|Bacteria 2|Bacteria EG spore germination - - - - - - - - - - - - EamA k141_5854_2 882083.SacmaDRAFT_2363 8.05e-24 96.3 COG4828@1|root,COG4828@2|Bacteria,2IQJ3@201174|Actinobacteria,4E5QJ@85010|Pseudonocardiales 201174|Actinobacteria S Protein of unknown function (DUF1622) - - - - - - - - - - - - DUF1622 k141_28119_2 1453501.JELR01000002_gene435 5.04e-213 602.0 COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,1RNPZ@1236|Gammaproteobacteria,4643D@72275|Alteromonadaceae 1236|Gammaproteobacteria L May be involved in recombinational repair of damaged DNA recN GO:0000724,GO:0000725,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 - ko:K03631 - - - - ko00000,ko03400 - - - AAA_23,SMC_N k141_22528_1 42565.FP66_14315 8.4e-21 90.5 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XHGD@135619|Oceanospirillales 135619|Oceanospirillales T signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - - - - - - - - - - CBS,EAL,GGDEF,PAS_9 k141_22528_2 42565.FP66_14310 1.13e-50 175.0 COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1MVJY@1224|Proteobacteria,1RRCA@1236|Gammaproteobacteria,1XI8F@135619|Oceanospirillales 135619|Oceanospirillales T Diguanylate cyclase - - - - - - - - - - - - CBS,EAL,GGDEF k141_4497_1 1294265.JCM21738_3491 5.84e-31 109.0 2C5CS@1|root,33A0C@2|Bacteria,1VKIZ@1239|Firmicutes,4HRCC@91061|Bacilli,1ZJ2K@1386|Bacillus 91061|Bacilli S NETI protein yebG - - - - - - - - - - - NETI k141_9495_1 1280001.BAOA01000217_gene257 1.44e-146 416.0 COG0447@1|root,COG0447@2|Bacteria,1QTZ2@1224|Proteobacteria,1T1TZ@1236|Gammaproteobacteria,1XVFY@135623|Vibrionales 135623|Vibrionales H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) menB - 4.1.3.36 ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R07263 RC01923 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 k141_9495_2 1116375.VEJY3_04280 6.3e-131 378.0 COG1441@1|root,COG1441@2|Bacteria,1MV33@1224|Proteobacteria,1RRC0@1236|Gammaproteobacteria,1XTPS@135623|Vibrionales 135623|Vibrionales H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) menC GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.2.1.113 ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R04031 RC01053 ko00000,ko00001,ko00002,ko01000 - - - MR_MLE_C k141_3293_1 1279017.AQYJ01000021_gene2923 8.73e-82 259.0 COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,1RPHJ@1236|Gammaproteobacteria,464JR@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1960 Acyl-CoA dehydrogenases bcd - 1.3.8.1 ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 - R01175,R01178,R02661,R03172,R04751 RC00052,RC00068,RC00076,RC00120,RC00148 ko00000,ko00001,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N k141_15152_1 218284.CCDN010000008_gene4136 1.28e-42 151.0 COG0297@1|root,COG0297@2|Bacteria,1TQ4M@1239|Firmicutes,4HAVA@91061|Bacilli,1ZDBA@1386|Bacillus 91061|Bacilli G Synthesizes alpha-1,4-glucan chains using ADP-glucose glgA GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009011,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 M00565 R02421 RC00005 ko00000,ko00001,ko00002,ko01000,ko01003 - GT5 - Glyco_transf_5,Glycos_transf_1 k141_35581_1 265729.GS18_0215915 1.26e-42 151.0 28J8S@1|root,2Z93X@2|Bacteria,1TR80@1239|Firmicutes,4HBGG@91061|Bacilli,1ZCZ1@1386|Bacillus 91061|Bacilli S Spore germination protein gerXB - - - - - - - - - - - Spore_permease k141_22529_1 1279017.AQYJ01000027_gene1555 1.12e-39 145.0 COG3516@1|root,COG3517@1|root,COG3516@2|Bacteria,COG3517@2|Bacteria,1NAN0@1224|Proteobacteria,1S07D@1236|Gammaproteobacteria,46BEH@72275|Alteromonadaceae 1236|Gammaproteobacteria S Type VI secretion protein, EvpB/VC_A0108, tail sheath - - - ko:K11900 ko02025,map02025 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - T6SS_VipA,VipB k141_33008_1 223926.28808727 8.14e-103 310.0 2C2F5@1|root,32WND@2|Bacteria,1R7B4@1224|Proteobacteria,1RZJV@1236|Gammaproteobacteria,1XTNW@135623|Vibrionales 135623|Vibrionales - - VPA0561 - - - - - - - - - - - - k141_33008_2 1116375.VEJY3_21856 1.05e-59 201.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XVJY@135623|Vibrionales 135623|Vibrionales T COG0840 Methyl-accepting chemotaxis protein VPA0562 - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - 4HB_MCP_1,HAMP,MCPsignal k141_16428_2 450851.PHZ_c1394 3.54e-28 114.0 COG0733@1|root,COG0733@2|Bacteria,1MUZJ@1224|Proteobacteria,2TUE5@28211|Alphaproteobacteria,2KHYB@204458|Caulobacterales 204458|Caulobacterales S Sodium:neurotransmitter symporter family - - - ko:K03308 - - - - ko00000 2.A.22.4,2.A.22.5 - - SNF k141_11860_1 400668.Mmwyl1_0166 1.31e-09 60.1 2DM33@1|root,31HZ0@2|Bacteria,1RJQ4@1224|Proteobacteria,1S7SM@1236|Gammaproteobacteria,1XMCE@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_30439_1 1294265.JCM21738_4073 7.65e-86 257.0 COG1802@1|root,COG1802@2|Bacteria,1TSJY@1239|Firmicutes,4HBY3@91061|Bacilli,1ZCQF@1386|Bacillus 91061|Bacilli K transcriptional gntR - - ko:K11476 - - - - ko00000,ko03000 - - - FCD,GntR k141_30439_2 349520.PPE_04828 2.72e-19 85.9 COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,4H9W6@91061|Bacilli,26TKU@186822|Paenibacillaceae 91061|Bacilli G Belongs to the FGGY kinase family gntK - 2.7.1.12 ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 - R01737 RC00002,RC00017 ko00000,ko00001,ko01000 - - - FGGY_C,FGGY_N k141_31599_1 218284.CCDN010000002_gene2587 9.36e-114 332.0 COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,4HA09@91061|Bacilli,1ZBT5@1386|Bacillus 91061|Bacilli K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG) tagU GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - - - - - - - - - - LytR_cpsA_psr k141_4498_1 218284.CCDN010000001_gene510 9.4e-66 205.0 COG2186@1|root,COG2186@2|Bacteria,1V3Z4@1239|Firmicutes,4HG61@91061|Bacilli,1ZQ57@1386|Bacillus 91061|Bacilli K helix_turn_helix gluconate operon transcriptional repressor lutR_1 - - ko:K05799 - - - - ko00000,ko03000 - - - FCD,GntR k141_1130_2 218284.CCDN010000001_gene149 9.72e-249 691.0 COG1982@1|root,COG1982@2|Bacteria,1TNZ9@1239|Firmicutes,4HBGC@91061|Bacilli,1ZAR0@1386|Bacillus 91061|Bacilli E Arginine speA GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008923,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564 4.1.1.17,4.1.1.19 ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 M00133,M00134 R00566,R00670 RC00299 ko00000,ko00001,ko00002,ko01000 - - - OKR_DC_1,OKR_DC_1_C k141_28121_1 218284.CCDN010000007_gene3908 2.09e-135 392.0 COG3314@1|root,COG3314@2|Bacteria,1TR35@1239|Firmicutes,4HAB6@91061|Bacilli,1ZARZ@1386|Bacillus 91061|Bacilli S protein conserved in bacteria - - - - - - - - - - - - Gate k141_26124_1 1450694.BTS2_2467 2e-31 120.0 COG3424@1|root,COG3424@2|Bacteria,1TPUK@1239|Firmicutes,4HBHH@91061|Bacilli,1ZC8W@1386|Bacillus 91061|Bacilli Q Naringenin-chalcone synthase bcsA - - ko:K16167 - - - - ko00000,ko01008 - - - Chal_sti_synt_C,Chal_sti_synt_N k141_29507_1 459349.CLOAM0406 6.47e-10 58.9 COG1734@1|root,COG1734@2|Bacteria,2NPX2@2323|unclassified Bacteria 2|Bacteria T Transcriptional regulator, TraR DksA family - - - ko:K06204 ko02026,map02026 - - - ko00000,ko00001,ko03000,ko03009,ko03021 - - - zf-dskA_traR k141_8209_1 42565.FP66_10040 4.15e-125 361.0 COG1177@1|root,COG1177@2|Bacteria,1MVC5@1224|Proteobacteria,1RQB7@1236|Gammaproteobacteria,1XI6A@135619|Oceanospirillales 135619|Oceanospirillales E ABC transporter permease - - - ko:K11070,ko:K11074 ko02010,map02010 M00299,M00300 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.1,3.A.1.11.2 - - BPD_transp_1 k141_28456_1 42565.FP66_09010 3.76e-68 220.0 COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,1RN3R@1236|Gammaproteobacteria,1XHH7@135619|Oceanospirillales 135619|Oceanospirillales J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) gltX - 6.1.1.17 ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 - - - tRNA-synt_1c k141_28456_2 42565.FP66_09015 1.32e-24 98.6 COG1028@1|root,COG1028@2|Bacteria,1RAEZ@1224|Proteobacteria,1S615@1236|Gammaproteobacteria,1XK04@135619|Oceanospirillales 135619|Oceanospirillales IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - - - - - - - - - - adh_short k141_8210_1 1120953.AUBH01000008_gene277 3.82e-82 252.0 COG3588@1|root,COG3588@2|Bacteria,1MVFK@1224|Proteobacteria,1RPMI@1236|Gammaproteobacteria,466BS@72275|Alteromonadaceae 1236|Gammaproteobacteria G aldolase fda - 4.1.2.13 ko:K01623 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000,ko03036,ko04131,ko04147 - - - Glycolytic k141_28457_1 1294265.JCM21738_516 7.31e-54 173.0 COG2112@1|root,COG2112@2|Bacteria,1UIYE@1239|Firmicutes,4ISX4@91061|Bacilli,1ZF0H@1386|Bacillus 91061|Bacilli T serine threonine protein kinase yrzF - - - - - - - - - - - Pkinase k141_31811_3 1453501.JELR01000006_gene26 9.4e-22 87.4 COG4736@1|root,COG4736@2|Bacteria 2|Bacteria O Cbb3-type cytochrome oxidase ccoQ - - ko:K00407 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002 3.D.4.3 - - FixQ k141_8211_1 218284.CCDN010000002_gene2777 9.98e-102 322.0 COG0369@1|root,COG2124@1|root,COG0369@2|Bacteria,COG2124@2|Bacteria,1TS1E@1239|Firmicutes,4HCWS@91061|Bacilli,1ZQAP@1386|Bacillus 91061|Bacilli C Belongs to the cytochrome P450 family yrhJ GO:0000166,GO:0003674,GO:0003824,GO:0003958,GO:0004497,GO:0005488,GO:0005504,GO:0005506,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008289,GO:0009987,GO:0010181,GO:0016491,GO:0016651,GO:0016653,GO:0016705,GO:0016712,GO:0019395,GO:0019752,GO:0020037,GO:0030258,GO:0031406,GO:0032553,GO:0032787,GO:0033293,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363 1.14.14.1,1.6.2.4 ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 - R03629,R04121,R05259 RC00046,RC01311 ko00000,ko00001,ko00199,ko01000 - - - FAD_binding_1,Flavodoxin_1,NAD_binding_1,p450 k141_36719_1 589873.EP13_17165 2.48e-107 333.0 COG4774@1|root,COG4774@2|Bacteria,1MV0X@1224|Proteobacteria,1RN3C@1236|Gammaproteobacteria,464QQ@72275|Alteromonadaceae 1236|Gammaproteobacteria P TonB dependent receptor - - - ko:K16090 - - - - ko00000,ko02000 1.B.14.1.11 - - Plug,TonB_dep_Rec k141_30684_2 1042377.AFPJ01000009_gene217 5.86e-138 399.0 COG0679@1|root,COG0679@2|Bacteria,1N1X9@1224|Proteobacteria,1RMV0@1236|Gammaproteobacteria,466VU@72275|Alteromonadaceae 1236|Gammaproteobacteria S Auxin Efflux Carrier - - - ko:K07088 - - - - ko00000 - - - Mem_trans k141_8212_1 218284.CCDN010000001_gene1198 2.8e-56 178.0 COG0262@1|root,COG0262@2|Bacteria,1VB80@1239|Firmicutes,4HIGJ@91061|Bacilli,1ZG71@1386|Bacillus 91061|Bacilli H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis dfrA - 1.5.1.3 ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 M00126,M00840 R00936,R00937,R00939,R00940,R02235,R02236,R11765 RC00109,RC00110,RC00158 ko00000,ko00001,ko00002,ko01000 - - - DHFR_1 k141_8269_1 574375.BAGA_05130 2.29e-30 121.0 COG0189@1|root,COG0189@2|Bacteria,1TRXK@1239|Firmicutes,4HBN0@91061|Bacilli,1ZE4C@1386|Bacillus 91061|Bacilli HJ YheC/D like ATP-grasp - - 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 - R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - ATPgrasp_YheCD,Mur_ligase_C,Mur_ligase_M k141_31868_2 218284.CCDN010000001_gene698 1.89e-138 392.0 COG0572@1|root,COG0572@2|Bacteria,1TQ4V@1239|Firmicutes,4HAVR@91061|Bacilli,1ZB2B@1386|Bacillus 91061|Bacilli F Cytidine monophosphokinase udk GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.48 ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PRK k141_31868_3 218284.CCDN010000001_gene699 8.36e-99 288.0 COG0782@1|root,COG0782@2|Bacteria,1V44S@1239|Firmicutes,4HGZU@91061|Bacilli,1ZFQI@1386|Bacillus 91061|Bacilli K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides greA GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - ko:K03624 - - - - ko00000,ko03021 - - - GreA_GreB,GreA_GreB_N k141_15389_1 218284.CCDN010000001_gene748 1.98e-173 488.0 COG1702@1|root,COG1702@2|Bacteria,1TP35@1239|Firmicutes,4HBD5@91061|Bacilli,1ZBVE@1386|Bacillus 91061|Bacilli T Phosphate starvation-inducible protein PhoH phoH - - ko:K06217 - - - - ko00000 - - - PhoH k141_15389_2 218284.CCDN010000001_gene747 3.27e-58 191.0 COG0561@1|root,COG0561@2|Bacteria,1TR3N@1239|Firmicutes,4HC8P@91061|Bacilli,1ZBP7@1386|Bacillus 91061|Bacilli S Stage IV sporulation yqfD - - ko:K06438 - - - - ko00000 - - - YqfD k141_38023_1 1116375.VEJY3_17746 3.26e-137 393.0 COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,1RSQ3@1236|Gammaproteobacteria,1XTPX@135623|Vibrionales 135623|Vibrionales P COG2897 Rhodanese-related sulfurtransferase sseA - 2.8.1.1,2.8.1.2 ko:K01011 ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122 - R01931,R03105,R03106 RC00214 ko00000,ko00001,ko01000 - - - Rhodanese k141_38023_2 674977.VMC_30240 1.35e-159 449.0 COG0476@1|root,COG0476@2|Bacteria,1MW7H@1224|Proteobacteria,1RPJ3@1236|Gammaproteobacteria,1XTIB@135623|Vibrionales 135623|Vibrionales H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 moeB - 2.7.7.80 ko:K21029 ko04122,map04122 - R07459 RC00043 ko00000,ko00001,ko01000 - - - ThiF k141_38023_3 1116375.VEJY3_17761 1.86e-46 159.0 COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,1RMQU@1236|Gammaproteobacteria,1XSIM@135623|Vibrionales 135623|Vibrionales H molybdopterin biosynthesis moeA - 2.10.1.1 ko:K03750 ko00790,ko01100,map00790,map01100 - R09735 RC03462 ko00000,ko00001,ko01000 - - - MoCF_biosynth,MoeA_C,MoeA_N k141_30751_1 318161.Sden_2427 2.15e-135 419.0 COG1629@1|root,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria,2Q8IQ@267890|Shewanellaceae 1236|Gammaproteobacteria P TonB-dependent receptor plug - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_31869_1 574376.BAMA_12810 1.84e-125 360.0 COG2197@1|root,COG2197@2|Bacteria,1TRXG@1239|Firmicutes,4HHRB@91061|Bacilli,1ZAZ5@1386|Bacillus 91061|Bacilli T helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE,Response_reg k141_31869_2 1078085.HMPREF1210_03094 1.93e-97 301.0 COG4585@1|root,COG4585@2|Bacteria,1V3N2@1239|Firmicutes,4HHKF@91061|Bacilli,26GPX@186818|Planococcaceae 91061|Bacilli T Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - - - - - - - - - - GAF,HATPase_c,HisKA_3 k141_8274_1 861299.J421_5870 5.2e-14 68.9 COG1595@1|root,COG1595@2|Bacteria,1ZTNR@142182|Gemmatimonadetes 2|Bacteria K Sigma-70 region 2 - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_8274_2 379066.GAU_2724 1.37e-10 64.3 2F756@1|root,33ZKP@2|Bacteria,1ZU38@142182|Gemmatimonadetes 142182|Gemmatimonadetes - - - - - - - - - - - - - - - k141_31870_2 42565.FP66_09540 2.38e-92 283.0 COG4623@1|root,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,1RM8W@1236|Gammaproteobacteria,1XI7H@135619|Oceanospirillales 135619|Oceanospirillales M Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella mltF GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - ko:K18691 - - - - ko00000,ko01000,ko01011 - - - SBP_bac_3,SLT k141_28505_1 1453501.JELR01000002_gene1234 0.0 971.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPES@1236|Gammaproteobacteria,464G8@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0488 ATPase components of ABC transporters with duplicated ATPase domains yheS GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K06158 - - - - ko00000,ko03012 - - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn k141_28505_2 1279017.AQYJ01000027_gene1913 2.36e-86 266.0 COG2885@1|root,COG2885@2|Bacteria 2|Bacteria M chlorophyll binding - - - - - - - - - - - - CHU_C,Calx-beta,DUF11,DUF4842,FG-GAP_2,Laminin_G_3,OMP_b-brl,PD40,TSP_3 k141_28505_3 1279017.AQYJ01000027_gene1912 9.48e-149 422.0 COG0220@1|root,COG0220@2|Bacteria,1MUWJ@1224|Proteobacteria,1RMFG@1236|Gammaproteobacteria,464N4@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA trmB GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 ko:K03439 - - - - ko00000,ko01000,ko03016 - - - Methyltransf_4 k141_28505_4 1279017.AQYJ01000027_gene1911 3.17e-52 167.0 COG2363@1|root,COG2363@2|Bacteria,1MZX3@1224|Proteobacteria,1SCNB@1236|Gammaproteobacteria,468G6@72275|Alteromonadaceae 1236|Gammaproteobacteria S small membrane protein ygdD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - DUF423 k141_38027_1 218284.CCDN010000003_gene2989 2.56e-131 404.0 COG1197@1|root,COG1197@2|Bacteria,1TPF1@1239|Firmicutes,4H9NB@91061|Bacilli,1ZBAK@1386|Bacillus 91061|Bacilli L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd - - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF k141_28506_1 1453501.JELR01000002_gene435 1.85e-146 427.0 COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,1RNPZ@1236|Gammaproteobacteria,4643D@72275|Alteromonadaceae 1236|Gammaproteobacteria L May be involved in recombinational repair of damaged DNA recN GO:0000724,GO:0000725,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 - ko:K03631 - - - - ko00000,ko03400 - - - AAA_23,SMC_N k141_28506_2 1453501.JELR01000002_gene436 4.21e-43 144.0 COG0204@1|root,COG0204@2|Bacteria,1RJMS@1224|Proteobacteria,1S71V@1236|Gammaproteobacteria,467SS@72275|Alteromonadaceae 1236|Gammaproteobacteria I Phosphate acyltransferases - - - - - - - - - - - - Acyltransferase k141_15393_1 1242864.D187_007430 1.61e-43 157.0 COG0477@1|root,COG2814@2|Bacteria,1NU31@1224|Proteobacteria,43CB2@68525|delta/epsilon subdivisions,2X7MH@28221|Deltaproteobacteria 28221|Deltaproteobacteria EGP Major facilitator superfamily MFS_1 - - - - - - - - - - - - MFS_1 k141_8279_1 218284.CCDN010000001_gene1795 6.6e-129 377.0 COG0174@1|root,COG0174@2|Bacteria,1TNZA@1239|Firmicutes,4HACE@91061|Bacilli,1ZBIQ@1386|Bacillus 91061|Bacilli E glutamine synthetase glnA GO:0003674,GO:0005488,GO:0005515,GO:0006082,GO:0006355,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0006808,GO:0007154,GO:0007584,GO:0008134,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009605,GO:0009719,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016053,GO:0016597,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043392,GO:0043436,GO:0043562,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0045892,GO:0045934,GO:0046394,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051098,GO:0051100,GO:0051101,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0061984,GO:0065007,GO:0065009,GO:0070406,GO:0070887,GO:0071310,GO:0071417,GO:0071495,GO:0071496,GO:0071704,GO:0080090,GO:0090293,GO:0090295,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901698,GO:1901699,GO:1902679,GO:1903506,GO:1903507,GO:1904796,GO:1904797,GO:2000112,GO:2000113,GO:2000677,GO:2000678,GO:2001141 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C,Gln-synt_N k141_15394_1 218284.CCDN010000002_gene1979 1.26e-102 300.0 COG1225@1|root,COG1225@2|Bacteria,1V24A@1239|Firmicutes,4HFUX@91061|Bacilli,1ZEQT@1386|Bacillus 91061|Bacilli O Redoxin - - - - - - - - - - - - AhpC-TSA k141_38028_1 1116375.VEJY3_11320 0.0 1161.0 COG0665@1|root,COG4121@1|root,COG0665@2|Bacteria,COG4121@2|Bacteria,1MZW5@1224|Proteobacteria,1RMTE@1236|Gammaproteobacteria,1XSRW@135623|Vibrionales 135623|Vibrionales J Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 mnmC GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0004808,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016491,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0055114,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.61 ko:K15461 - - R00601,R08702 RC00003,RC00053,RC00060,RC01483 ko00000,ko01000,ko03016 - - - DAO,Methyltransf_30 k141_38028_2 1116375.VEJY3_11325 6.1e-103 300.0 COG0431@1|root,COG0431@2|Bacteria,1RH7F@1224|Proteobacteria,1SWZ0@1236|Gammaproteobacteria,1XT0Z@135623|Vibrionales 135623|Vibrionales S flavoprotein - - - - - - - - - - - - FMN_red k141_30760_1 1347369.CCAD010000019_gene1383 9.37e-51 172.0 COG3290@1|root,COG3290@2|Bacteria,1VK8U@1239|Firmicutes,4HR8P@91061|Bacilli,1ZEI5@1386|Bacillus 91061|Bacilli T GHKL domain natK - 2.7.13.3 ko:K11640 ko02020,map02020 M00494 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c_5,SPOB_a k141_38030_1 218284.CCDN010000001_gene552 3.34e-63 201.0 COG1039@1|root,COG1039@2|Bacteria,1TQBE@1239|Firmicutes,4H9QR@91061|Bacilli,1ZBHW@1386|Bacillus 91061|Bacilli L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhC GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03471 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DUF3378,RNase_HII k141_30761_1 316274.Haur_1250 1.87e-33 130.0 COG0477@1|root,COG2814@2|Bacteria,2G7YK@200795|Chloroflexi,376E9@32061|Chloroflexia 32061|Chloroflexia EGP PFAM major facilitator superfamily MFS_1 - - - ko:K08217 - - - - br01600,ko00000,ko01504,ko02000 2.A.1.21.1,2.A.1.21.22 - - MFS_1 k141_15395_1 1453501.JELR01000002_gene1504 3.92e-154 438.0 COG2267@1|root,COG2267@2|Bacteria,1RAQZ@1224|Proteobacteria,1S2YX@1236|Gammaproteobacteria,467BE@72275|Alteromonadaceae 1236|Gammaproteobacteria I Serine aminopeptidase, S33 pldB - 3.1.1.5 ko:K01048 ko00564,map00564 - - - ko00000,ko00001,ko01000 - - - Hydrolase_4 k141_8282_1 1042377.AFPJ01000010_gene1461 1.16e-108 330.0 COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,1RNPT@1236|Gammaproteobacteria,464DV@72275|Alteromonadaceae 1236|Gammaproteobacteria C The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) aceF - 2.3.1.12 ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding k141_28509_1 218284.CCDN010000001_gene1429 1.57e-138 394.0 COG2013@1|root,COG2013@2|Bacteria,1TPN2@1239|Firmicutes,4H9P0@91061|Bacilli,1ZERN@1386|Bacillus 91061|Bacilli S Mitochondrial biogenesis AIM24 - - - - - - - - - - - - AIM24 k141_28509_2 218284.CCDN010000001_gene1430 4.11e-96 290.0 COG0552@1|root,COG0552@2|Bacteria,1TR66@1239|Firmicutes,4HDEI@91061|Bacilli,1ZDQ2@1386|Bacillus 91061|Bacilli U protein localization to endoplasmic reticulum - - - - - - - - - - - - - k141_15396_1 218284.CCDN010000001_gene1213 5.78e-42 154.0 COG0840@1|root,COG0840@2|Bacteria,1UV22@1239|Firmicutes,4IBKM@91061|Bacilli,1ZERB@1386|Bacillus 91061|Bacilli NT CHASE3 domain - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - CHASE3,MCPsignal k141_28510_1 218284.CCDN010000001_gene672 4.62e-05 44.7 COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,4HACD@91061|Bacilli,1ZBXI@1386|Bacillus 91061|Bacilli J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) aspS - 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - GAD,tRNA-synt_2,tRNA_anti-codon k141_8283_1 1294265.JCM21738_3486 2.89e-107 318.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HA2A@91061|Bacilli,1ZBG3@1386|Bacillus 91061|Bacilli I acyl-CoA dehydrogenase mmgC - - ko:K18244 - - - - ko00000,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_31871_2 1279017.AQYJ01000025_gene610 1.06e-63 199.0 COG5608@1|root,COG5608@2|Bacteria,1MZF0@1224|Proteobacteria,1SEGD@1236|Gammaproteobacteria,468MK@72275|Alteromonadaceae 1236|Gammaproteobacteria S Late embryogenesis abundant protein - - - - - - - - - - - - LEA_2 k141_31871_5 1453501.JELR01000001_gene2110 9.19e-95 289.0 2EIJE@1|root,33CAQ@2|Bacteria,1NH29@1224|Proteobacteria,1SGJY@1236|Gammaproteobacteria,46969@72275|Alteromonadaceae 1236|Gammaproteobacteria S Psort location CytoplasmicMembrane, score - - - - - - - - - - - - - k141_31871_7 1280954.HPO_11002 1.91e-40 143.0 COG3803@1|root,COG3803@2|Bacteria,1RHYI@1224|Proteobacteria,2U7AN@28211|Alphaproteobacteria,43XV7@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Bacterial protein of unknown function (DUF924) - - - - - - - - - - - - DUF924 k141_31871_8 1279017.AQYJ01000029_gene3492 3.09e-86 260.0 COG1280@1|root,COG1280@2|Bacteria,1RDPB@1224|Proteobacteria,1S5JJ@1236|Gammaproteobacteria,4681J@72275|Alteromonadaceae 1236|Gammaproteobacteria E LysE type translocator - - - - - - - - - - - - LysE k141_28511_1 665959.HMPREF1013_01403 3.21e-26 114.0 COG0860@1|root,COG3103@1|root,COG0860@2|Bacteria,COG3103@2|Bacteria,1UYPW@1239|Firmicutes,4HBVT@91061|Bacilli,1ZDI1@1386|Bacillus 91061|Bacilli M COG3103 SH3 domain protein - - 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - Amidase_3,Cu_amine_oxidN1,PG_binding_1,SH3_3,SH3_4,SH3_8,SLH k141_31873_1 314265.R2601_10859 6.53e-90 270.0 COG3485@1|root,COG3485@2|Bacteria,1MV6K@1224|Proteobacteria,2TUS4@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q intradiol ring-cleavage dioxygenase - - - - - - - - - - - - Dioxygenase_C k141_31873_2 1185766.DL1_06510 6.41e-13 66.2 COG3576@1|root,COG3576@2|Bacteria,1MWG9@1224|Proteobacteria,2TSKK@28211|Alphaproteobacteria,2XP9Q@285107|Thioclava 28211|Alphaproteobacteria S Pyridoxamine 5'-phosphate oxidase MA20_21430 - - ko:K07006 - - - - ko00000 - - - Putative_PNPOx k141_38037_1 1123242.JH636434_gene3635 3.54e-07 58.5 COG1572@1|root,COG2931@1|root,COG1572@2|Bacteria,COG2931@2|Bacteria,2J2V8@203682|Planctomycetes 203682|Planctomycetes Q calcium- and calmodulin-responsive adenylate cyclase activity - - - - - - - - - - - - - k141_28513_1 1279017.AQYJ01000023_gene3141 2.05e-109 323.0 COG0821@1|root,COG0821@2|Bacteria,1MUAX@1224|Proteobacteria,1RMXZ@1236|Gammaproteobacteria,464MT@72275|Alteromonadaceae 1236|Gammaproteobacteria I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate ispG GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046429,GO:0046490,GO:0046872,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R08689,R10859 RC01486 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b2515,iAPECO1_1312.APECO1_4009,iB21_1397.B21_02369,iBWG_1329.BWG_2279,iE2348C_1286.E2348C_2798,iEC55989_1330.EC55989_2800,iECABU_c1320.ECABU_c28200,iECBD_1354.ECBD_1171,iECB_1328.ECB_02407,iECDH10B_1368.ECDH10B_2681,iECDH1ME8569_1439.ECDH1ME8569_2442,iECDH1ME8569_1439.EcDH1_1153,iECD_1391.ECD_02407,iECED1_1282.ECED1_2946,iECH74115_1262.ECH74115_3740,iECIAI39_1322.ECIAI39_2716,iECNA114_1301.ECNA114_2593,iECO103_1326.ECO103_3032,iECO111_1330.ECO111_3239,iECO26_1355.ECO26_3562,iECOK1_1307.ECOK1_2863,iECP_1309.ECP_2520,iECS88_1305.ECS88_2691,iECSE_1348.ECSE_2801,iECSF_1327.ECSF_2359,iECSP_1301.ECSP_3455,iECW_1372.ECW_m2740,iECs_1301.ECs3377,iEKO11_1354.EKO11_1218,iETEC_1333.ETEC_2672,iEcDH1_1363.EcDH1_1153,iEcE24377_1341.EcE24377A_2799,iEcolC_1368.EcolC_1162,iJO1366.b2515,iJR904.b2515,iLF82_1304.LF82_1130,iNRG857_1313.NRG857_12515,iUMN146_1321.UM146_04130,iUMNK88_1353.UMNK88_3165,iUTI89_1310.UTI89_C2836,iWFL_1372.ECW_m2740,iY75_1357.Y75_RS13130,iYL1228.KPN_02845,iZ_1308.Z3778,ic_1306.c3037 GcpE k141_8286_2 218284.CCDN010000002_gene2304 3.57e-18 80.5 COG5522@1|root,COG5522@2|Bacteria,1V57K@1239|Firmicutes,4HHZD@91061|Bacilli,1ZCPD@1386|Bacillus 91061|Bacilli S Integral membrane protein (intg_mem_TP0381) - - - - - - - - - - - - Intg_mem_TP0381 k141_15400_1 218284.CCDN010000001_gene1012 2.04e-105 314.0 COG1215@1|root,COG1215@2|Bacteria,1UYDS@1239|Firmicutes,4HD6I@91061|Bacilli,1ZPVD@1386|Bacillus 91061|Bacilli M COG0463 Glycosyltransferases involved in cell wall biogenesis - - - - - - - - - - - - Glycos_transf_2 k141_30764_1 1279017.AQYJ01000025_gene685 1.35e-33 119.0 COG1694@1|root,COG1694@2|Bacteria,1N02D@1224|Proteobacteria,1SGNT@1236|Gammaproteobacteria,46CTZ@72275|Alteromonadaceae 1236|Gammaproteobacteria S MazG-like family - - - - - - - - - - - - MazG-like k141_31874_2 1090320.KB900605_gene3031 2.01e-13 74.3 COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2TT4A@28211|Alphaproteobacteria,2K7F9@204457|Sphingomonadales 204457|Sphingomonadales C CoA-transferase family III - - - - - - - - - - - - CoA_transf_3 k141_8287_1 218284.CCDN010000001_gene1135 2.5e-18 84.0 COG0438@1|root,COG0438@2|Bacteria,1TPS8@1239|Firmicutes,4HA43@91061|Bacilli,1ZASJ@1386|Bacillus 91061|Bacilli M N-acetyl-alpha-D-glucosaminyl L-malate synthase bshA - - ko:K00754 - - - - ko00000,ko01000 - GT4 - Glyco_transf_4,Glycos_transf_1 k141_8287_2 218284.CCDN010000001_gene1136 4.18e-113 338.0 COG0617@1|root,COG0617@2|Bacteria,1TQ2A@1239|Firmicutes,4HB2W@91061|Bacilli,1ZC20@1386|Bacillus 91061|Bacilli J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate cca - 2.7.7.72 ko:K00974 ko03013,map03013 - R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016 - - - PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2 k141_36747_1 1116375.VEJY3_14940 3.21e-134 382.0 COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,1RN21@1236|Gammaproteobacteria,1XTTV@135623|Vibrionales 135623|Vibrionales J Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle rsmD - 2.1.1.171 ko:K08316 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - Cons_hypoth95 k141_36747_2 1116375.VEJY3_14935 4.05e-233 649.0 COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,1RNIN@1236|Gammaproteobacteria,1XUBA@135623|Vibrionales 135623|Vibrionales U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components ftsY - - ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2,3.A.5.7 - - SRP54,SRP54_N k141_36747_3 1219076.N646_2051 5.46e-158 443.0 COG2884@1|root,COG2884@2|Bacteria,1MVQ4@1224|Proteobacteria,1RMZA@1236|Gammaproteobacteria,1XSS6@135623|Vibrionales 135623|Vibrionales D Cell division ATP-binding protein FtsE ftsE - - ko:K09812 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - ABC_tran k141_36747_4 1116375.VEJY3_14925 5.93e-199 555.0 COG2177@1|root,COG2177@2|Bacteria,1MU65@1224|Proteobacteria,1RYBV@1236|Gammaproteobacteria,1XUCE@135623|Vibrionales 135623|Vibrionales D Part of the ABC transporter FtsEX involved in cellular division ftsX - - ko:K09811 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - FtsX k141_36747_5 1219076.N646_2049 1.19e-196 546.0 COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,1RMFR@1236|Gammaproteobacteria,1XTFM@135623|Vibrionales 135623|Vibrionales K RNA polymerase sigma rpoH GO:0000988,GO:0000990,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016020,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043254,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - ko:K03089 - - - - ko00000,ko03021 - - - Sigma70_r1_2,Sigma70_r2,Sigma70_r4 k141_36747_6 1280001.BAOA01000088_gene3628 6.47e-68 206.0 COG0607@1|root,COG0607@2|Bacteria,1MZPW@1224|Proteobacteria,1S94C@1236|Gammaproteobacteria,1XXT2@135623|Vibrionales 135623|Vibrionales P Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide glpE GO:0003674,GO:0003824 2.8.1.1 ko:K02439 ko00920,ko01110,ko01120,map00920,map01110,map01120 - R01931 - ko00000,ko00001,ko01000 - - - Rhodanese k141_36747_7 1116375.VEJY3_14910 1.16e-180 505.0 COG0705@1|root,COG0705@2|Bacteria,1MYPM@1224|Proteobacteria,1RN1K@1236|Gammaproteobacteria,1XSZ8@135623|Vibrionales 135623|Vibrionales S membrane protein (homolog of Drosophila rhomboid) glpG - - ko:K02441 - - - - ko00000 - - - Rhomboid,Rhomboid_N k141_36747_8 1116375.VEJY3_14905 7.25e-86 253.0 COG1580@1|root,COG1580@2|Bacteria,1N0RT@1224|Proteobacteria,1S9SJ@1236|Gammaproteobacteria,1XXJ9@135623|Vibrionales 135623|Vibrionales N Controls the rotational direction of flagella during chemotaxis - - - ko:K02415 - - - - ko00000,ko02035 - - - FliL k141_36747_9 223926.28807975 3.62e-119 341.0 COG3161@1|root,COG3161@2|Bacteria,1N8BF@1224|Proteobacteria,1S6A0@1236|Gammaproteobacteria,1XWEG@135623|Vibrionales 135623|Vibrionales H Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway ubiC GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008813,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.1.3.40 ko:K03181 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R01302 RC00491,RC02148 ko00000,ko00001,ko00002,ko01000 - - - Chor_lyase k141_36747_10 223926.28807974 2.04e-192 535.0 COG0382@1|root,COG0382@2|Bacteria,1MV4Q@1224|Proteobacteria,1RMZ1@1236|Gammaproteobacteria,1XT4I@135623|Vibrionales 135623|Vibrionales H Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate ubiA GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008412,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.39 ko:K03179 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R05000,R05615 RC00209,RC02895 ko00000,ko00001,ko00002,ko01000,ko01006 - - - UbiA k141_36747_11 1116375.VEJY3_14890 0.0 1477.0 COG2937@1|root,COG2937@2|Bacteria,1MWZ6@1224|Proteobacteria,1RM7K@1236|Gammaproteobacteria,1XUC5@135623|Vibrionales 135623|Vibrionales I Belongs to the GPAT DAPAT family plsB GO:0003674,GO:0003824,GO:0004366,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0071704,GO:0090407,GO:1901576 2.3.1.15 ko:K00631 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase k141_28514_1 42565.FP66_14055 7.35e-310 865.0 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,1RMPV@1236|Gammaproteobacteria,1XHDT@135619|Oceanospirillales 135619|Oceanospirillales F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdA - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN k141_30766_1 218284.CCDN010000001_gene529 3.34e-127 364.0 COG1971@1|root,COG1971@2|Bacteria,1V4BC@1239|Firmicutes,4HH29@91061|Bacilli,1ZCPR@1386|Bacillus 91061|Bacilli P Probably functions as a manganese efflux pump ytaF - - - - - - - - - - - Mntp k141_31876_2 218284.CCDN010000002_gene2891 7.63e-46 154.0 COG1120@1|root,COG1120@2|Bacteria,1TP2Q@1239|Firmicutes,4HADG@91061|Bacilli,1ZBMI@1386|Bacillus 91061|Bacilli HP ABC transporter fhuC - 3.6.3.34 ko:K02013 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 - - ABC_tran k141_28515_1 218284.CCDN010000001_gene1199 5.38e-114 330.0 COG1272@1|root,COG1272@2|Bacteria,1TSFK@1239|Firmicutes,4HAT2@91061|Bacilli,1ZBJJ@1386|Bacillus 91061|Bacilli S protein, Hemolysin III yplQ - - ko:K11068 - - - - ko00000,ko02042 - - - HlyIII k141_15401_1 1042377.AFPJ01000038_gene1100 5.19e-157 460.0 COG4774@1|root,COG4774@2|Bacteria,1NMCN@1224|Proteobacteria,1T3TQ@1236|Gammaproteobacteria,46DC7@72275|Alteromonadaceae 1236|Gammaproteobacteria P TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_13303_1 42565.FP66_00905 6.63e-115 341.0 COG1167@1|root,COG1167@2|Bacteria,1MV6F@1224|Proteobacteria,1RMQ0@1236|Gammaproteobacteria,1XI6W@135619|Oceanospirillales 135619|Oceanospirillales K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs - - - - - - - - - - - - Aminotran_1_2,GntR k141_10856_2 218284.CCDN010000011_gene4413 2.63e-58 181.0 COG0234@1|root,COG0234@2|Bacteria,1V9ZM@1239|Firmicutes,4HKEK@91061|Bacilli,1ZGZ1@1386|Bacillus 91061|Bacilli O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter groS GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - ko:K04078 - - - - ko00000,ko03029,ko03110 - - - Cpn10 k141_37005_1 1453501.JELR01000001_gene2848 7.96e-46 162.0 COG3693@1|root,COG3693@2|Bacteria,1MX93@1224|Proteobacteria,1RZMK@1236|Gammaproteobacteria,4652G@72275|Alteromonadaceae 1236|Gammaproteobacteria G Glycosyl hydrolase family 10 - - 3.2.1.8 ko:K01181 - - - - ko00000,ko01000 - - - CBM_10,CBM_2,CBM_4_9,Glyco_hydro_10 k141_286_1 1340434.AXVA01000029_gene42 3.53e-53 175.0 COG0294@1|root,COG0294@2|Bacteria,1TPKT@1239|Firmicutes,4H9SY@91061|Bacilli,1ZAPZ@1386|Bacillus 91061|Bacilli H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives folP GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.15 ko:K00796 ko00790,ko01100,map00790,map01100 M00126,M00841 R03066,R03067 RC00121,RC00842 ko00000,ko00001,ko00002,ko01000 - - - Pterin_bind k141_286_2 218284.CCDN010000003_gene3013 5.85e-68 207.0 COG1539@1|root,COG1539@2|Bacteria,1VA0I@1239|Firmicutes,4HKKK@91061|Bacilli,1ZGZ7@1386|Bacillus 91061|Bacilli H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin folB - 1.13.11.81,4.1.2.25,5.1.99.8 ko:K01633 ko00790,ko01100,map00790,map01100 M00126,M00840 R03504,R11037,R11073 RC00721,RC00943,RC01479,RC03333,RC03334 ko00000,ko00001,ko00002,ko01000 - - - FolB k141_3802_2 493475.GARC_4062 2.18e-49 161.0 2DMKI@1|root,32S70@2|Bacteria,1N1FV@1224|Proteobacteria,1S778@1236|Gammaproteobacteria,46BB3@72275|Alteromonadaceae 1236|Gammaproteobacteria S SpoIIAA-like VVA0543 - - - - - - - - - - - SpoIIAA-like k141_3802_3 1279017.AQYJ01000028_gene2386 2.2e-57 186.0 COG3945@1|root,COG3945@2|Bacteria,1NE2M@1224|Proteobacteria,1SD78@1236|Gammaproteobacteria,4695P@72275|Alteromonadaceae 1236|Gammaproteobacteria S Hemerythrin HHE cation binding domain - - - - - - - - - - - - Hemerythrin k141_3802_4 1279017.AQYJ01000028_gene2378 9.85e-87 263.0 COG3047@1|root,COG3047@2|Bacteria,1NUZJ@1224|Proteobacteria,1RRRC@1236|Gammaproteobacteria,467CK@72275|Alteromonadaceae 1236|Gammaproteobacteria M Outer membrane protein W ompW - - ko:K07275 - - - - ko00000 - - - OmpW k141_6236_1 42565.FP66_14960 1.3e-73 236.0 COG3288@1|root,COG3288@2|Bacteria,1MVXU@1224|Proteobacteria,1RN23@1236|Gammaproteobacteria,1XIDN@135619|Oceanospirillales 135619|Oceanospirillales C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane pntA - 1.6.1.2 ko:K00324 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - AlaDh_PNT_C,AlaDh_PNT_N,PNTB_4TM k141_14485_1 1294265.JCM21738_124 1.89e-79 247.0 COG0128@1|root,COG0128@2|Bacteria,1TPIH@1239|Firmicutes,4HBHZ@91061|Bacilli,1ZBP0@1386|Bacillus 91061|Bacilli E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate aroA GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03460 RC00350 ko00000,ko00001,ko00002,ko01000 - - - EPSP_synthase k141_14485_2 1294265.JCM21738_123 3.9e-100 292.0 COG0287@1|root,COG0287@2|Bacteria,1TPXG@1239|Firmicutes,4HBI4@91061|Bacilli,1ZBVZ@1386|Bacillus 91061|Bacilli E prephenate dehydrogenase tyrA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.3.1.12 ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00025 R01728 RC00125 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU22610 ACT,PDH k141_12109_1 42565.FP66_09240 8.2e-102 313.0 COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,1RNM8@1236|Gammaproteobacteria,1XIDU@135619|Oceanospirillales 135619|Oceanospirillales C Catalyzes the formation of trans-2- enoyl-CoA from 2,4-dienoyl-CoA fadH - 1.3.1.34 ko:K00219 - - - - ko00000,ko01000 - - - Oxidored_FMN,Pyr_redox_2 k141_287_1 1279017.AQYJ01000018_gene826 2.42e-74 236.0 COG3104@1|root,COG3104@2|Bacteria,1QUVH@1224|Proteobacteria,1T22D@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Major facilitator superfamily - - - - - - - - - - - - MFS_1,MFS_3 k141_28775_1 1280001.BAOA01000027_gene4796 7.75e-52 177.0 COG1757@1|root,COG1757@2|Bacteria,1MY5C@1224|Proteobacteria,1RP6I@1236|Gammaproteobacteria,1XSDA@135623|Vibrionales 135623|Vibrionales C COG1757 Na H antiporter - - - ko:K18218 - M00667 - - ko00000,ko00002,ko01504,ko02000 - - - Na_H_antiporter k141_28775_2 223926.28806120 4.63e-68 208.0 COG2916@1|root,COG2916@2|Bacteria,1R9YM@1224|Proteobacteria,1S24H@1236|Gammaproteobacteria,1XXBR@135623|Vibrionales 135623|Vibrionales K Belongs to the histone-like protein H-NS family hns - - ko:K03746 - - - - ko00000,ko03036,ko03400 - - - Histone_HNS k141_28775_3 1219076.N646_0182 5.38e-307 837.0 COG0524@1|root,COG0524@2|Bacteria,1MUUC@1224|Proteobacteria,1RMN2@1236|Gammaproteobacteria,1XTRF@135623|Vibrionales 135623|Vibrionales G COG0524 Sugar kinases, ribokinase family - - 2.7.1.73 ko:K00892 ko00230,map00230 - R01131,R01228 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB k141_28775_4 674977.VMC_32520 4.14e-54 169.0 2E8FY@1|root,332U8@2|Bacteria,1N8EY@1224|Proteobacteria,1SD25@1236|Gammaproteobacteria,1XYDE@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_28775_5 1219076.N646_0180 2.04e-276 755.0 COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,1RMAK@1236|Gammaproteobacteria,1XU0P@135623|Vibrionales 135623|Vibrionales J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 mnmA GO:0001510,GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0003824,GO:0004808,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.8.1.13 ko:K00566 ko04122,map04122 - R08700 RC02313,RC02315 ko00000,ko00001,ko01000,ko03016 - - - tRNA_Me_trans k141_28775_6 1116375.VEJY3_05515 1.29e-133 380.0 COG2915@1|root,COG2915@2|Bacteria,1RI8B@1224|Proteobacteria,1RPCC@1236|Gammaproteobacteria,1XT1A@135623|Vibrionales 135623|Vibrionales S High frequency lysogenization protein HflD homolog hflD - - ko:K07153 - - - - ko00000 - - - DUF489 k141_28775_7 945550.VISI1226_18191 0.0 888.0 COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,1RN93@1236|Gammaproteobacteria,1XT6I@135623|Vibrionales 135623|Vibrionales F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily purB - 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 - - - ASL_C,Lyase_1 k141_28775_8 1280001.BAOA01000027_gene4804 2.39e-97 286.0 2ANPA@1|root,31DNS@2|Bacteria,1RHTE@1224|Proteobacteria,1S2Z7@1236|Gammaproteobacteria,1XWZY@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF3833) - - - - - - - - - - - - DUF3833 k141_28775_9 1280001.BAOA01000027_gene4805 3.23e-89 266.0 COG3572@1|root,COG3572@2|Bacteria,1RKWZ@1224|Proteobacteria,1S89R@1236|Gammaproteobacteria,1XXU8@135623|Vibrionales 135623|Vibrionales H ergothioneine biosynthetic process - - - - - - - - - - - - Chalcone_3 k141_28775_10 1116375.VEJY3_05495 2.69e-86 257.0 2DM7V@1|root,323W3@2|Bacteria,1NPYM@1224|Proteobacteria,1SJ13@1236|Gammaproteobacteria,1XY2N@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF2878) - - - - - - - - - - - - DUF2878 k141_28775_11 1116375.VEJY3_05490 6.25e-259 714.0 COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,1RNID@1236|Gammaproteobacteria,1XSW4@135623|Vibrionales 135623|Vibrionales M COG2230 Cyclopropane fatty acid synthase and related methyltransferases cfa - 2.1.1.79 ko:K00574 - - - - ko00000,ko01000 - - - CMAS k141_28775_12 1116375.VEJY3_05485 7.91e-172 482.0 COG3496@1|root,COG3496@2|Bacteria,1RC56@1224|Proteobacteria,1RRT8@1236|Gammaproteobacteria,1XW4E@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF1365) - - - ko:K09701 - - - - ko00000 - - - DUF1365 k141_28775_13 1116375.VEJY3_05480 1.67e-276 760.0 COG2907@1|root,COG2907@2|Bacteria,1MV4Z@1224|Proteobacteria,1RP4P@1236|Gammaproteobacteria,1XSW6@135623|Vibrionales 135623|Vibrionales S NAD FAD-binding protein - - - - - - - - - - - - Amino_oxidase k141_28775_14 1116375.VEJY3_05475 3.55e-135 387.0 COG0300@1|root,COG0300@2|Bacteria,1N9YK@1224|Proteobacteria,1T1TA@1236|Gammaproteobacteria,1Y32C@135623|Vibrionales 135623|Vibrionales S COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - - - - - - - - - - adh_short k141_28775_15 1116375.VEJY3_05470 1.39e-80 240.0 COG3631@1|root,COG3631@2|Bacteria,1MZS5@1224|Proteobacteria,1S8VN@1236|Gammaproteobacteria,1XXE4@135623|Vibrionales 135623|Vibrionales S SnoaL-like domain - - - - - - - - - - - - SnoaL_2 k141_28775_16 1116375.VEJY3_05465 1.37e-190 531.0 COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,1RMN0@1236|Gammaproteobacteria,1XSVQ@135623|Vibrionales 135623|Vibrionales O Belongs to the peptidase M48B family htpX GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0050896 - ko:K03799 - M00743 - - ko00000,ko00002,ko01000,ko01002 - - - Peptidase_M48 k141_28775_17 1116375.VEJY3_05460 8.61e-32 110.0 2AWMV@1|root,31NIK@2|Bacteria,1QK99@1224|Proteobacteria,1TICQ@1236|Gammaproteobacteria,1XYVP@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_28775_18 1280001.BAOA01000027_gene4814 2.94e-132 377.0 COG0132@1|root,COG0132@2|Bacteria,1RDRK@1224|Proteobacteria,1RSHS@1236|Gammaproteobacteria,1XSF9@135623|Vibrionales 135623|Vibrionales H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring bioD GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.3 ko:K01935 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R03182 RC00868 ko00000,ko00001,ko00002,ko01000 - - - AAA_26 k141_306_1 1056820.KB900637_gene161 1.84e-21 87.8 COG4650@1|root,COG4650@2|Bacteria,1PFIH@1224|Proteobacteria,1RWVJ@1236|Gammaproteobacteria,2PQEW@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria K regulator - - - ko:K14414 - - - - ko00000,ko03000 - - - - k141_18110_1 1294265.JCM21738_2283 4.95e-162 472.0 COG2202@1|root,COG5002@1|root,COG2202@2|Bacteria,COG5002@2|Bacteria,1VUBP@1239|Firmicutes,4HUPW@91061|Bacilli,1ZS15@1386|Bacillus 91061|Bacilli T Histidine kinase kinA - 2.7.13.3 ko:K02491 ko02020,map02020 M00485 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - 5TM-5TMR_LYT,HATPase_c,HisKA,MASE3,MHYT,PAS,PAS_3,PAS_4,PAS_9 k141_3826_1 926550.CLDAP_35150 2.29e-101 318.0 COG0495@1|root,COG0495@2|Bacteria,2G5MX@200795|Chloroflexi 200795|Chloroflexi J Belongs to the class-I aminoacyl-tRNA synthetase family leuS - 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Anticodon_1,tRNA-synt_1,tRNA-synt_1_2 k141_6266_1 1294265.JCM21738_2661 6.81e-144 415.0 COG0332@1|root,COG0332@2|Bacteria,1TRHZ@1239|Firmicutes,4HDJ2@91061|Bacilli,1ZB47@1386|Bacillus 91061|Bacilli I COG0332 3-oxoacyl- acyl-carrier-protein synthase III - - 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACP_syn_III,ACP_syn_III_C k141_2625_1 218284.CCDN010000002_gene2038 3.55e-167 496.0 COG0457@1|root,COG0457@2|Bacteria,1UATF@1239|Firmicutes,4HE1D@91061|Bacilli,1ZBPM@1386|Bacillus 91061|Bacilli S ATPase. Has a role at an early stage in the morphogenesis of the spore coat - - - - - - - - - - - - Dynamin_N,TPR_8 k141_25183_1 1453501.JELR01000001_gene2143 1.47e-66 234.0 COG0501@1|root,COG0501@2|Bacteria,1NAW7@1224|Proteobacteria,1SFEN@1236|Gammaproteobacteria,46C96@72275|Alteromonadaceae 1236|Gammaproteobacteria O Belongs to the peptidase M48B family - - - - - - - - - - - - Peptidase_M48 k141_12133_1 1453501.JELR01000005_gene1575 2.65e-143 431.0 COG1175@1|root,COG2182@1|root,COG1175@2|Bacteria,COG2182@2|Bacteria,1MXKR@1224|Proteobacteria,1RN6B@1236|Gammaproteobacteria,46801@72275|Alteromonadaceae 1236|Gammaproteobacteria G COG1175 ABC-type sugar transport systems, permease components malF GO:0003674,GO:0003824,GO:0005215,GO:0005363,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006950,GO:0006974,GO:0008150,GO:0008643,GO:0009987,GO:0015144,GO:0015154,GO:0015157,GO:0015399,GO:0015405,GO:0015422,GO:0015423,GO:0015766,GO:0015768,GO:0015772,GO:0015774,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0033037,GO:0033554,GO:0034219,GO:0042623,GO:0042626,GO:0042956,GO:0043190,GO:0043211,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990060,GO:1990351 - ko:K10109,ko:K15771 ko02010,map02010 M00194,M00491 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.1,3.A.1.1.16,3.A.1.1.2,3.A.1.1.22 - iZ_1308.Z5631 BPD_transp_1,MalF_P2 k141_12133_2 1123320.KB889670_gene3587 1.11e-118 355.0 COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria 201174|Actinobacteria E Belongs to the ABC transporter superfamily - - - ko:K10112 ko02010,map02010 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1 - - ABC_tran,TOBE_2 k141_12133_4 1453501.JELR01000002_gene593 1.39e-250 695.0 COG1473@1|root,COG1473@2|Bacteria,1MUIV@1224|Proteobacteria,1RQAM@1236|Gammaproteobacteria,465BJ@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG1473 Metal-dependent amidase aminoacylase carboxypeptidase amaA - - ko:K01436 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 k141_29888_1 665959.HMPREF1013_00992 8.72e-64 201.0 COG2197@1|root,COG2197@2|Bacteria,1TRXG@1239|Firmicutes,4HCCV@91061|Bacilli,1ZDBY@1386|Bacillus 91061|Bacilli K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain yhcZ - - ko:K02479 - - - - ko00000,ko02022 - - - GerE,Response_reg k141_29888_2 1294265.JCM21738_1977 2.24e-14 66.6 2E2U4@1|root,32XW8@2|Bacteria,1VAT9@1239|Firmicutes,4HN53@91061|Bacilli,1ZHZK@1386|Bacillus 91061|Bacilli S YhdB-like protein yhdB - - - - - - - - - - - YhdB k141_6267_2 218284.CCDN010000001_gene551 2.38e-52 181.0 COG0072@1|root,COG0072@2|Bacteria,1TP98@1239|Firmicutes,4HAQ9@91061|Bacilli,1ZB8G@1386|Bacillus 91061|Bacilli J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily pheT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - B3_4,B5,FDX-ACB,tRNA_bind k141_3827_1 218284.CCDN010000004_gene3121 4.03e-119 352.0 COG0591@1|root,COG0591@2|Bacteria,1TPVE@1239|Firmicutes,4H9KW@91061|Bacilli,1ZB64@1386|Bacillus 91061|Bacilli E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - ko:K11928 - - - - ko00000,ko02000 2.A.21.2 - - SSF k141_9686_1 1121933.AUHH01000032_gene1951 1.18e-138 406.0 COG0457@1|root,COG0457@2|Bacteria,2I3ME@201174|Actinobacteria,4DWWY@85009|Propionibacteriales 201174|Actinobacteria S Tetratricopeptide repeat - - - - - - - - - - - - - k141_26430_1 1042377.AFPJ01000008_gene2004 2.95e-43 154.0 COG1012@1|root,COG1012@2|Bacteria,1NRUR@1224|Proteobacteria,1SMSX@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Aldehyde dehydrogenase family - - - - - - - - - - - - Aldedh k141_26430_2 1042377.AFPJ01000008_gene2005 8.81e-167 471.0 COG2513@1|root,COG2513@2|Bacteria,1N4VT@1224|Proteobacteria,1RMR5@1236|Gammaproteobacteria,464GF@72275|Alteromonadaceae 1236|Gammaproteobacteria G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate - - - - - - - - - - - - PEP_mutase k141_26430_3 1042377.AFPJ01000008_gene2006 5.07e-95 283.0 2CHK1@1|root,2ZBVE@2|Bacteria,1NYW8@1224|Proteobacteria,1SPYQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Red chlorophyll catabolite reductase (RCC reductase) - - - - - - - - - - - - RCC_reductase k141_20357_1 1224746.B932_1028 8.16e-96 307.0 COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,2TSFF@28211|Alphaproteobacteria,2JPMB@204441|Rhodospirillales 204441|Rhodospirillales E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor gcvP - 1.4.4.2 ko:K00281,ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko00002,ko01000 - - - Aminotran_5,GDC-P k141_10877_1 218284.CCDN010000011_gene4402 1.02e-86 256.0 COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,4HIKU@91061|Bacilli,1ZGAT@1386|Bacillus 91061|Bacilli K This enzyme acetylates the N-terminal alanine of ribosomal protein S18 rimI - 2.3.1.128 ko:K03789 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_1 k141_1370_2 218284.CCDN010000005_gene3199 1.21e-84 254.0 COG1234@1|root,COG1234@2|Bacteria,1V1TF@1239|Firmicutes,4HFNV@91061|Bacilli,1ZCZE@1386|Bacillus 91061|Bacilli S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III yhfI GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 - - - - - - - - - - Lactamase_B,Lactamase_B_2 k141_4937_1 1004785.AMBLS11_04085 4.77e-284 807.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria,46ABP@72275|Alteromonadaceae 1236|Gammaproteobacteria P receptor - - - - - - - - - - - - Plug,STN,TonB_dep_Rec k141_4937_2 1127673.GLIP_2699 2.11e-20 90.9 COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,1RPU5@1236|Gammaproteobacteria,46411@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0471 Di- and tricarboxylate transporters sdcS - - ko:K14445 - - - - ko00000,ko02000 2.A.47.1 - - Na_sulph_symp k141_25184_2 1034347.CAHJ01000044_gene4896 2.41e-36 128.0 COG2832@1|root,COG2832@2|Bacteria,1VEWF@1239|Firmicutes,4HNT4@91061|Bacilli,1ZHC8@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF454) ybaN - - ko:K09790 - - - - ko00000 - - - DUF454 k141_7363_2 218284.CCDN010000004_gene3122 7.47e-133 389.0 COG0415@1|root,COG0415@2|Bacteria,1TQAK@1239|Firmicutes,4HB9K@91061|Bacilli,1ZCI5@1386|Bacillus 91061|Bacilli L Belongs to the DNA photolyase family phrB - 4.1.99.3 ko:K01669 - - - - ko00000,ko01000,ko03400 - - - DNA_photolyase,FAD_binding_7 k141_27517_1 796606.BMMGA3_16240 1.71e-89 265.0 COG3465@1|root,COG3465@2|Bacteria,1V6Q4@1239|Firmicutes,4HHX3@91061|Bacilli,1ZFMJ@1386|Bacillus 91061|Bacilli - - ywgA - - ko:K09388 - - - - ko00000 - - - - k141_27517_2 1294265.JCM21738_1762 2.16e-64 207.0 COG1078@1|root,COG1078@2|Bacteria,1TPVB@1239|Firmicutes,4HAX8@91061|Bacilli,1ZBRB@1386|Bacillus 91061|Bacilli S COG1078 HD superfamily phosphohydrolases ywfO GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 - ko:K06885 - - - - ko00000 - - - HD k141_26431_2 1279017.AQYJ01000028_gene2414 1.04e-75 238.0 COG1716@1|root,COG1716@2|Bacteria,1MXT7@1224|Proteobacteria,1SAKZ@1236|Gammaproteobacteria,468KA@72275|Alteromonadaceae 1236|Gammaproteobacteria T Forkhead associated domain - - - - - - - - - - - - FHA,Yop-YscD_cpl k141_13318_1 1453501.JELR01000002_gene1187 5.02e-150 431.0 COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,1RN0F@1236|Gammaproteobacteria,465EB@72275|Alteromonadaceae 1236|Gammaproteobacteria T Signal transduction histidine kinase phoR - 2.7.13.3 ko:K07636 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - DUF3329,HATPase_c,HisKA,PAS,PAS_8 k141_22787_1 218284.CCDN010000005_gene3194 2.84e-83 260.0 COG1232@1|root,COG1232@2|Bacteria,1TQ6W@1239|Firmicutes,4HAUG@91061|Bacilli,1ZANK@1386|Bacillus 91061|Bacilli H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX hemY - 1.3.3.15,1.3.3.4 ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03222,R04178 RC00885 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS09325 Amino_oxidase k141_22787_2 218284.CCDN010000005_gene3193 1.63e-203 565.0 COG0276@1|root,COG0276@2|Bacteria,1TPKF@1239|Firmicutes,4HAYG@91061|Bacilli,1ZAZ6@1386|Bacillus 91061|Bacilli H Catalyzes the ferrous insertion into protoporphyrin IX hemH GO:0003674,GO:0003824,GO:0004325,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R00310,R11329 RC01012 ko00000,ko00001,ko00002,ko01000 - - - Ferrochelatase k141_308_2 1279017.AQYJ01000027_gene1833 2.9e-39 142.0 COG0508@1|root,COG0508@2|Bacteria,1MVDC@1224|Proteobacteria,1RQ9Y@1236|Gammaproteobacteria,4657Y@72275|Alteromonadaceae 1236|Gammaproteobacteria C 2-oxoacid dehydrogenases acyltransferase (catalytic domain) pdhC - 2.3.1.12,2.3.1.168 ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 M00036,M00307 R00209,R02569,R02662,R03174,R04097,R10998 RC00004,RC02727,RC02742,RC02857,RC02870 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding k141_4938_1 342113.DM82_5675 1.82e-49 180.0 COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,2VKDG@28216|Betaproteobacteria,1K5EP@119060|Burkholderiaceae 28216|Betaproteobacteria G Glycosyl hydrolase 36 superfamily, catalytic domain - - - ko:K13688 - - - - ko00000,ko01000,ko01003 - GH94,GT84 - Glyco_hydro_36,Glyco_transf_36,Glycoamylase k141_12134_2 1042377.AFPJ01000012_gene1387 6.87e-116 342.0 COG3346@1|root,COG3346@2|Bacteria,1MZUH@1224|Proteobacteria,1S8S0@1236|Gammaproteobacteria,4684Q@72275|Alteromonadaceae 1236|Gammaproteobacteria S SURF1-like protein surf1 - - ko:K14998 - - - - ko00000,ko03029 3.D.4.8 - - SURF1 k141_16839_1 1042377.AFPJ01000024_gene774 3.91e-26 106.0 COG0438@1|root,COG0438@2|Bacteria,1MUTA@1224|Proteobacteria,1RS31@1236|Gammaproteobacteria,465ZQ@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0438 Glycosyltransferase waaG - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 k141_33484_1 42565.FP66_10345 1.81e-150 427.0 COG2355@1|root,COG2355@2|Bacteria,1MWEW@1224|Proteobacteria,1RQGU@1236|Gammaproteobacteria,1XR14@135619|Oceanospirillales 135619|Oceanospirillales E Peptidase M19 - - 3.4.13.19 ko:K01273 - - - - ko00000,ko00537,ko01000,ko01002,ko04147 - - - Peptidase_M19 k141_3828_1 1453501.JELR01000002_gene868 5.42e-258 730.0 COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,1RYP9@1236|Gammaproteobacteria,465IE@72275|Alteromonadaceae 1236|Gammaproteobacteria E ERAP1-like C-terminal domain - - 3.4.11.14 ko:K01263 - - - - ko00000,ko01000 - - - ERAP1_C,Peptidase_M1 k141_22788_1 1211814.CAPG01000008_gene302 9.92e-84 254.0 COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,4HA2S@91061|Bacilli,1ZAUS@1386|Bacillus 91061|Bacilli P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components oppB - - ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - BPD_transp_1 k141_22788_2 1347086.CCBA010000027_gene3467 3.31e-18 82.8 COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4H9PZ@91061|Bacilli,1ZC9B@1386|Bacillus 91061|Bacilli EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components oppC - - ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - BPD_transp_1,OppC_N k141_21656_1 1294265.JCM21738_67 8.79e-175 492.0 COG4955@1|root,COG4955@2|Bacteria,1TQU9@1239|Firmicutes,4HFUR@91061|Bacilli,1ZDGR@1386|Bacillus 91061|Bacilli S protein conserved in bacteria ypbB - 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 - - - HTH_40,RQC k141_26432_1 1283299.AUKG01000001_gene3274 1.34e-05 49.3 COG1990@1|root,COG1990@2|Bacteria,2HR74@201174|Actinobacteria,4CT30@84995|Rubrobacteria 84995|Rubrobacteria S Peptidyl-tRNA hydrolase PTH2 - - - - - - - - - - - - PTH2 k141_26432_2 218284.CCDN010000001_gene1316 2.76e-49 159.0 COG0346@1|root,COG0346@2|Bacteria,1VMX2@1239|Firmicutes,4HR63@91061|Bacilli,1ZGDM@1386|Bacillus 91061|Bacilli E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - Glyoxalase k141_2628_1 218284.CCDN010000006_gene3685 8.71e-111 342.0 COG0653@1|root,COG0653@2|Bacteria,1TPEY@1239|Firmicutes,4HA22@91061|Bacilli,1ZAXF@1386|Bacillus 91061|Bacilli U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW k141_6271_1 1127673.GLIP_2897 9.12e-39 143.0 COG4973@1|root,COG4973@2|Bacteria,1MUJJ@1224|Proteobacteria,1RMJG@1236|Gammaproteobacteria,465QJ@72275|Alteromonadaceae 1236|Gammaproteobacteria D Belongs to the 'phage' integrase family. XerC subfamily xerC GO:0000150,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008907,GO:0009009,GO:0009037,GO:0009987,GO:0015074,GO:0032991,GO:0034641,GO:0042150,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0071139,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - ko:K03733 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase k141_26433_1 1156919.QWC_12548 8.21e-30 119.0 2CK1H@1|root,33WMM@2|Bacteria,1RF5H@1224|Proteobacteria 1224|Proteobacteria S Protein of unknown function (DUF4043) - - - - - - - - - - - - DUF4043 k141_12136_1 935836.JAEL01000071_gene4038 3.85e-72 221.0 COG5553@1|root,COG5553@2|Bacteria,1VFPC@1239|Firmicutes,4HPUH@91061|Bacilli,1ZFM7@1386|Bacillus 91061|Bacilli S Cysteine dioxygenase type I cdoA - 1.13.11.20 ko:K00456 ko00270,ko00430,ko01100,map00270,map00430,map01100 - R00893 RC00404 ko00000,ko00001,ko01000 - - - CDO_I k141_13319_1 218284.CCDN010000001_gene1481 6.05e-51 166.0 COG0503@1|root,COG0503@2|Bacteria,1V1DU@1239|Firmicutes,4HFNW@91061|Bacilli,1ZFTS@1386|Bacillus 91061|Bacilli F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis xpt - 2.4.2.22 ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 - R01229,R02142 RC00063,RC00122 ko00000,ko00001,ko01000 - - iYO844.BSU22070 Pribosyltran k141_13319_2 1345697.M493_10600 2.75e-56 185.0 COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,1TPE2@1239|Firmicutes,4H9WH@91061|Bacilli,1WHA0@129337|Geobacillus 91061|Bacilli P Rhodanese Homology Domain - - - - - - - - - - - - Lactamase_B,Rhodanese k141_1372_1 768710.DesyoDRAFT_0700 1.25e-15 73.9 COG0745@1|root,COG0745@2|Bacteria,1TP9M@1239|Firmicutes 1239|Firmicutes T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain saeR - - ko:K10682 ko02020,map02020 M00468 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C k141_1372_2 1294265.JCM21738_2380 3.1e-73 226.0 COG5000@1|root,COG5000@2|Bacteria 2|Bacteria T phosphorelay sensor kinase activity - - 2.7.13.3 ko:K07675 ko02020,map02020 M00473 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA_3,PAS_4,sCache_3_2 k141_6272_1 218284.CCDN010000009_gene4315 6.55e-44 157.0 COG0601@1|root,COG1173@1|root,COG0601@2|Bacteria,COG1173@2|Bacteria,1V21B@1239|Firmicutes,4HDPU@91061|Bacilli,1ZEQ7@1386|Bacillus 91061|Bacilli EP Binding-protein-dependent transport system inner membrane component - - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1,Peptidase_M1 k141_6272_2 218284.CCDN010000009_gene4316 4.12e-58 182.0 2BNM3@1|root,32HA0@2|Bacteria,1V6TF@1239|Firmicutes,4HJ5U@91061|Bacilli,1ZHKY@1386|Bacillus 91061|Bacilli S Pathogenicity locus - - - - - - - - - - - - Cdd1 k141_22790_1 1123236.KB899386_gene1853 1.69e-117 345.0 COG2885@1|root,COG2885@2|Bacteria,1R8DG@1224|Proteobacteria,1RP3K@1236|Gammaproteobacteria,466H7@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the ompA family - - - ko:K03286 - - - - ko00000,ko02000 1.B.6 - - OMP_b-brl,OmpA,OmpA_membrane,TSP_3 k141_33485_1 1121921.KB898706_gene2447 6.57e-73 245.0 2DB7A@1|root,2Z7KK@2|Bacteria,1PI5G@1224|Proteobacteria,1RQHS@1236|Gammaproteobacteria,2PN9I@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria S Glycosyl hydrolase family 115 - - - - - - - - - - - - Glyco_hydro_115,Glyco_hydro_67N k141_4082_1 1453501.JELR01000002_gene1345 1.55e-40 141.0 COG2961@1|root,COG2961@2|Bacteria,1MWGA@1224|Proteobacteria,1RNI1@1236|Gammaproteobacteria,466GS@72275|Alteromonadaceae 1236|Gammaproteobacteria S Specifically methylates the adenine in position 2030 of 23S rRNA rlmJ GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008988,GO:0009451,GO:0009987,GO:0010467,GO:0015976,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036307,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.266 ko:K07115 - - - - ko00000,ko01000,ko03009 - - - RsmJ k141_9992_1 218284.CCDN010000001_gene728 8.25e-116 342.0 COG0860@1|root,COG0860@2|Bacteria,1TSFS@1239|Firmicutes,4HACZ@91061|Bacilli,1ZAV0@1386|Bacillus 91061|Bacilli M stage II sporulation protein P spoIIP - - ko:K06385 - - - - ko00000 - - - SpoIIP k141_27636_1 1453501.JELR01000001_gene2484 5.63e-34 118.0 2EHUF@1|root,33BK2@2|Bacteria,1NMAC@1224|Proteobacteria,1SGY0@1236|Gammaproteobacteria,46950@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_12484_1 218284.CCDN010000005_gene3365 5.88e-200 566.0 COG1032@1|root,COG1032@2|Bacteria,1TPGT@1239|Firmicutes,4HA0Y@91061|Bacilli,1ZAU7@1386|Bacillus 91061|Bacilli C Fe-S oxidoreductase bchE - 1.21.98.3 ko:K04034 ko00860,ko01100,ko01110,map00860,map01100,map01110 - R06268,R06269,R06270 RC00741,RC01491,RC01492 ko00000,ko00001,ko01000 - - - B12-binding,DUF4080,Radical_SAM k141_24169_1 1116375.VEJY3_07500 5.12e-10 54.7 2B6Q4@1|root,31ZNW@2|Bacteria,1QKII@1224|Proteobacteria,1TINS@1236|Gammaproteobacteria,1XZDW@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_24169_2 945550.VISI1226_13753 6.44e-36 123.0 2EIY9@1|root,33CPF@2|Bacteria,1NNY6@1224|Proteobacteria,1SHUV@1236|Gammaproteobacteria,1XYDZ@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_23117_1 1294265.JCM21738_365 1.15e-145 419.0 COG0612@1|root,COG0612@2|Bacteria,1TP5I@1239|Firmicutes,4HBBF@91061|Bacilli,1ZDJE@1386|Bacillus 91061|Bacilli S Belongs to the peptidase M16 family mlpA - - - - - - - - - - - Peptidase_M16,Peptidase_M16_C k141_9993_2 218284.CCDN010000001_gene35 2.33e-17 75.9 COG1302@1|root,COG1302@2|Bacteria,1V731@1239|Firmicutes,4HIS4@91061|Bacilli,1ZG6I@1386|Bacillus 91061|Bacilli S protein conserved in bacteria yloU - - - - - - - - - - - Asp23 k141_37220_1 1294265.JCM21738_1748 1.9e-14 69.7 COG4506@1|root,COG4506@2|Bacteria,1VK4E@1239|Firmicutes,4HR38@91061|Bacilli,1ZHXY@1386|Bacillus 91061|Bacilli S protein conserved in bacteria ywiB - - - - - - - - - - - DUF1934 k141_37220_2 1294265.JCM21738_1747 1.57e-124 361.0 COG0018@1|root,COG0018@2|Bacteria,1TPEZ@1239|Firmicutes,4HAR3@91061|Bacilli,1ZBP1@1386|Bacillus 91061|Bacilli J Arginyl-tRNA synthetase argS GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d k141_27637_1 669262.COK_2244 2.64e-08 54.3 COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,1RPI8@1236|Gammaproteobacteria,1Y82B@135625|Pasteurellales 135625|Pasteurellales D Tyrosine recombinase XerD xerD - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase k141_31310_2 1238450.VIBNISOn1_p0045 6.36e-52 167.0 COG1670@1|root,COG1670@2|Bacteria,1RIR5@1224|Proteobacteria,1T0YU@1236|Gammaproteobacteria,1XXJK@135623|Vibrionales 135623|Vibrionales J Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_3 k141_569_1 1453501.JELR01000005_gene1665 1.27e-43 164.0 COG2982@1|root,COG2982@2|Bacteria,1MUME@1224|Proteobacteria,1RNPC@1236|Gammaproteobacteria,464KK@72275|Alteromonadaceae 1236|Gammaproteobacteria M Domain of Unknown Function (DUF748) - - - - - - - - - - - - DUF748,OmpA k141_15866_1 1033802.SSPSH_003250 1.8e-10 67.8 COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,1RPV3@1236|Gammaproteobacteria 1236|Gammaproteobacteria NU Tfp pilus assembly protein tip-associated adhesin PilY1 pilY1 - - ko:K02674 - - - - ko00000,ko02035,ko02044 - - - Neisseria_PilC k141_12486_1 218284.CCDN010000007_gene3923 9.58e-93 281.0 COG0842@1|root,COG0842@2|Bacteria,1TQG7@1239|Firmicutes,4H9MK@91061|Bacilli,1ZAPY@1386|Bacillus 91061|Bacilli V COG0842 ABC-type multidrug transport system, permease component - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane,ABC2_membrane_3 k141_570_1 218284.CCDN010000006_gene3710 5.11e-55 180.0 COG0697@1|root,COG0697@2|Bacteria,1UYSM@1239|Firmicutes,4HFBU@91061|Bacilli,1ZAQS@1386|Bacillus 91061|Bacilli EG EamA-like transporter family yoaV5 - - - - - - - - - - - EamA k141_23118_1 326297.Sama_0948 2.14e-126 373.0 COG0738@1|root,COG0738@2|Bacteria,1MXDC@1224|Proteobacteria,1RMQJ@1236|Gammaproteobacteria,2Q9D3@267890|Shewanellaceae 1236|Gammaproteobacteria G PFAM major facilitator superfamily MFS_1 gluP - - ko:K02429 - - - - ko00000,ko02000 2.A.1.7 - - MFS_1 k141_18343_4 1114856.C496_08581 4.08e-46 162.0 COG0500@1|root,arCOG01783@2157|Archaea,2XWBW@28890|Euryarchaeota,23UCS@183963|Halobacteria 183963|Halobacteria Q Methyltransferase type 11 - - - - - - - - - - - - Methyltransf_11,Methyltransf_25 k141_18343_5 1121937.AUHJ01000020_gene1274 9.36e-53 171.0 COG1846@1|root,COG1846@2|Bacteria,1MZY5@1224|Proteobacteria,1S98B@1236|Gammaproteobacteria,468Y4@72275|Alteromonadaceae 1236|Gammaproteobacteria K helix_turn_helix multiple antibiotic resistance protein - - - - - - - - - - - - MarR k141_18343_6 1279017.AQYJ01000028_gene2330 1.73e-157 453.0 COG1566@1|root,COG1566@2|Bacteria,1MU7I@1224|Proteobacteria,1RMAD@1236|Gammaproteobacteria,466Y4@72275|Alteromonadaceae 1236|Gammaproteobacteria V HlyD membrane-fusion protein of T1SS emrA - - ko:K03543 - M00701 - - ko00000,ko00002,ko02000 8.A.1.1 - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 k141_25459_2 1116375.VEJY3_24256 4.49e-232 639.0 COG4874@1|root,COG4874@2|Bacteria,1N05R@1224|Proteobacteria,1S34T@1236|Gammaproteobacteria,1XTBH@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria containing a pentein-type domain - - - - - - - - - - - - Amidinotransf k141_25459_3 223926.28810118 1.2e-123 357.0 COG2733@1|root,COG2733@2|Bacteria,1R4JT@1224|Proteobacteria,1RRVB@1236|Gammaproteobacteria,1XU14@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria - - - - - - - - - - - - DUF445 k141_25459_4 1169144.KB910928_gene1900 1.44e-06 47.8 COG1219@1|root,COG1219@2|Bacteria,1TQ00@1239|Firmicutes,4H9U4@91061|Bacilli,1ZANE@1386|Bacillus 91061|Bacilli O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP clpX GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - ko:K03544 ko04112,map04112 - - - ko00000,ko00001,ko03110 - - - AAA_2,ClpB_D2-small,zf-C4_ClpX k141_2780_1 1042377.AFPJ01000009_gene195 7.47e-24 93.6 COG1553@1|root,COG1553@2|Bacteria,1N021@1224|Proteobacteria,1S99J@1236|Gammaproteobacteria,467M1@72275|Alteromonadaceae 1236|Gammaproteobacteria P conserved protein involved in intracellular sulfur reduction tusD GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0019417,GO:0032991,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055114,GO:0071704,GO:0090304,GO:0097163,GO:0140104,GO:1901360,GO:1902494,GO:1990228,GO:1990234 - ko:K07235 ko04122,map04122 - - - ko00000,ko00001,ko01000,ko03016 - - - DrsE k141_2780_2 29495.EA26_19770 1.14e-17 79.0 COG2923@1|root,COG2923@2|Bacteria,1N8RV@1224|Proteobacteria,1SD0S@1236|Gammaproteobacteria,1XXV7@135623|Vibrionales 135623|Vibrionales P Belongs to the DsrF TusC family tusC - - ko:K07236 ko04122,map04122 - - - ko00000,ko00001,ko03016 - - - DrsE k141_7528_1 565045.NOR51B_1633 4.12e-83 262.0 COG1752@1|root,COG1752@2|Bacteria,1N5SK@1224|Proteobacteria,1RSDG@1236|Gammaproteobacteria 1236|Gammaproteobacteria S esterase of the alpha-beta hydrolase superfamily - - - - - - - - - - - - DUF3336,Patatin k141_37221_1 42565.FP66_06460 3.6e-170 512.0 COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,1RMK0@1236|Gammaproteobacteria,1XHCD@135619|Oceanospirillales 135619|Oceanospirillales K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoB - 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 k141_18344_1 1124780.ANNU01000044_gene475 2.98e-18 81.6 COG4974@1|root,COG4974@2|Bacteria,4NGB5@976|Bacteroidetes,47PJP@768503|Cytophagia 976|Bacteroidetes L Phage integrase family - - - - - - - - - - - - Phage_int_SAM_4,Phage_integrase k141_18344_2 768706.Desor_2212 6.59e-37 136.0 COG0517@1|root,COG0517@2|Bacteria,1TQ4J@1239|Firmicutes,24B68@186801|Clostridia,260BK@186807|Peptococcaceae 186801|Clostridia S Transposase - - - - - - - - - - - - Y2_Tnp,Zn_Tnp_IS91 k141_28956_1 518766.Rmar_2012 5.89e-142 421.0 COG4263@1|root,COG4263@2|Bacteria,4NFNE@976|Bacteroidetes,1FIVE@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes C Nitrous oxide reductase nosZ - 1.7.2.4 ko:K00376 ko00910,ko01120,map00910,map01120 M00529 R02804 RC02861 ko00000,ko00001,ko00002,ko01000 - - - - k141_15867_1 218284.CCDN010000001_gene67 5.7e-125 381.0 COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,4HAWB@91061|Bacilli,1ZAQK@1386|Bacillus 91061|Bacilli J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS - 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1,zf-FPG_IleRS k141_33767_1 1279017.AQYJ01000022_gene2666 1.03e-220 611.0 COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,1RNWY@1236|Gammaproteobacteria,464S4@72275|Alteromonadaceae 1236|Gammaproteobacteria L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing ruvB GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 3.6.4.12 ko:K03551 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvB_C,RuvB_N k141_33767_3 1279017.AQYJ01000022_gene2668 8.11e-142 402.0 COG0811@1|root,COG0811@2|Bacteria,1NCWW@1224|Proteobacteria,1RMD4@1236|Gammaproteobacteria,465HR@72275|Alteromonadaceae 1236|Gammaproteobacteria U COG0811 Biopolymer transport proteins tolQ GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0015893,GO:0016020,GO:0016021,GO:0017038,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0032153,GO:0033036,GO:0042221,GO:0042493,GO:0042886,GO:0042891,GO:0043213,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0050896,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - ko:K03562 ko01120,map01120 - - - ko00000,ko02000 1.A.30.2.2 - - MotA_ExbB k141_33767_4 1042377.AFPJ01000010_gene1476 4.77e-83 247.0 COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,1S8RS@1236|Gammaproteobacteria,4679Y@72275|Alteromonadaceae 1236|Gammaproteobacteria U Biopolymer transport protein tolR GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0015833,GO:0015893,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032153,GO:0042221,GO:0042493,GO:0042886,GO:0042891,GO:0043213,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - ko:K03560 - - - - ko00000,ko02000 1.A.30.2.2 - - ExbD k141_33767_5 1042377.AFPJ01000010_gene1475 7.26e-70 222.0 COG0810@1|root,COG0810@2|Bacteria,1RKRA@1224|Proteobacteria,1S83X@1236|Gammaproteobacteria,46CRY@72275|Alteromonadaceae 1236|Gammaproteobacteria M TonB C terminal - - - ko:K03646 - - - - ko00000,ko02000 2.C.1.2 - - TonB_2 k141_33767_6 1279017.AQYJ01000022_gene2671 7.13e-151 442.0 COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,1RMCY@1236|Gammaproteobacteria,464D7@72275|Alteromonadaceae 1236|Gammaproteobacteria U Involved in the TonB-independent uptake of proteins tolB GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015031,GO:0015833,GO:0015893,GO:0017038,GO:0019904,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0032991,GO:0033036,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0043213,GO:0044464,GO:0044877,GO:0045184,GO:0046677,GO:0046678,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0070887,GO:0071236,GO:0071237,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701 - ko:K03641 - - - - ko00000,ko02000 2.C.1.2 - - PD40,TolB_N k141_572_1 218284.CCDN010000001_gene197 1.23e-116 340.0 COG0598@1|root,COG0598@2|Bacteria,1TPSV@1239|Firmicutes,4HAPC@91061|Bacilli,1ZBVW@1386|Bacillus 91061|Bacilli P Mediates influx of magnesium ions corA - - ko:K03284 - - - - ko00000,ko02000 1.A.35.1,1.A.35.3 - - CorA k141_25460_2 1453501.JELR01000002_gene84 3.58e-76 246.0 COG4232@1|root,COG4233@1|root,COG4232@2|Bacteria,COG4233@2|Bacteria,1MU8W@1224|Proteobacteria,1RPF7@1236|Gammaproteobacteria,46550@72275|Alteromonadaceae 1236|Gammaproteobacteria CO Thiol disulfide interchange protein - - 1.8.1.8 ko:K04084 - - - - ko00000,ko01000,ko03110 5.A.1.1 - - DsbC,DsbD,Thioredoxin_7 k141_17066_1 1279017.AQYJ01000027_gene1653 4.7e-142 412.0 COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,1RMQU@1236|Gammaproteobacteria,4662Y@72275|Alteromonadaceae 1236|Gammaproteobacteria H COG0303 Molybdopterin biosynthesis enzyme moeA - 2.10.1.1 ko:K03750 ko00790,ko01100,map00790,map01100 - R09735 RC03462 ko00000,ko00001,ko01000 - - - MoCF_biosynth,MoeA_C,MoeA_N k141_13648_1 223926.28805564 5.12e-123 354.0 COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,1RM9U@1236|Gammaproteobacteria,1XV5N@135623|Vibrionales 135623|Vibrionales S Polyphosphate kinase 2 (PPK2) - - 2.7.4.1 ko:K22468 ko00190,ko03018,map00190,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - PPK2 k141_13648_2 223926.28805563 8.65e-159 446.0 COG0704@1|root,COG0704@2|Bacteria,1MUMI@1224|Proteobacteria,1RMW5@1236|Gammaproteobacteria,1XSNM@135623|Vibrionales 135623|Vibrionales P Plays a role in the regulation of phosphate uptake phoU - - ko:K02039 - - - - ko00000 - - - PhoU k141_13648_3 223926.28805562 3.84e-191 531.0 COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,1RNUF@1236|Gammaproteobacteria,1XSAI@135623|Vibrionales 135623|Vibrionales P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system pstB GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015114,GO:0015318,GO:0015399,GO:0015405,GO:0015415,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0035435,GO:0042623,GO:0042626,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0098660,GO:0098661,GO:0099133 3.6.3.27 ko:K02036 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 - - ABC_tran k141_13648_4 1116375.VEJY3_02630 0.0 1002.0 COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,1RPV9@1236|Gammaproteobacteria,1XTB7@135623|Vibrionales 135623|Vibrionales P phosphate transport system pstA - - ko:K02038 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 k141_20621_1 1116375.VEJY3_02745 0.0 1005.0 COG0443@1|root,COG0443@2|Bacteria,1MVQI@1224|Proteobacteria,1RN74@1236|Gammaproteobacteria,1XT9W@135623|Vibrionales 135623|Vibrionales O Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB hscA GO:0006457,GO:0008150,GO:0009987 - ko:K04044 - - - - ko00000,ko03110 1.A.33 - - HSP70 k141_17078_1 1307436.PBF_02270 2.15e-117 351.0 COG0069@1|root,COG0069@2|Bacteria,1TSHA@1239|Firmicutes,4HA97@91061|Bacilli,1ZCQH@1386|Bacillus 91061|Bacilli E Belongs to the glutamate synthase family yerD GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.7.1 ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 - R00021,R10086 RC00006,RC00010 ko00000,ko00001,ko01000 - - - Glu_synthase k141_1593_1 497321.C664_00880 3.74e-27 113.0 COG3174@1|root,COG3174@2|Bacteria,1NDBI@1224|Proteobacteria,2VJ4P@28216|Betaproteobacteria,2KUDC@206389|Rhodocyclales 206389|Rhodocyclales S Domain of unknown function (DUF4010) - - - - - - - - - - - - DUF4010,MgtC k141_26820_1 1042377.AFPJ01000044_gene631 1.03e-130 383.0 COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,1RMSE@1236|Gammaproteobacteria,464I1@72275|Alteromonadaceae 1236|Gammaproteobacteria E Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia trpE - 4.1.3.27 ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_0417 Anth_synt_I_N,Chorismate_bind k141_26820_2 1042377.AFPJ01000044_gene630 1.19e-151 427.0 COG0036@1|root,COG0036@2|Bacteria,1MUZM@1224|Proteobacteria,1RN3K@1236|Gammaproteobacteria,465KW@72275|Alteromonadaceae 1236|Gammaproteobacteria G Belongs to the ribulose-phosphate 3-epimerase family rpe GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0046914,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 - - iPC815.YPO0155,iYL1228.KPN_03757 Ribul_P_3_epim k141_15881_1 861299.J421_3338 1e-23 100.0 COG1530@1|root,COG1530@2|Bacteria,1ZSZS@142182|Gemmatimonadetes 142182|Gemmatimonadetes J Ribonuclease E/G family - - - ko:K08301 - - - - ko00000,ko01000,ko03009,ko03019 - - - RNase_E_G k141_21855_1 1453501.JELR01000002_gene243 1.92e-198 580.0 COG3188@1|root,COG3188@2|Bacteria,1PTRC@1224|Proteobacteria,1S047@1236|Gammaproteobacteria 1236|Gammaproteobacteria NU E-set like domain cblC - - - - - - - - - - - CooC_C,TcfC,Usher_TcfC k141_25483_1 218284.CCDN010000001_gene993 3.17e-118 343.0 COG0834@1|root,COG0834@2|Bacteria,1TT16@1239|Firmicutes,4HU0X@91061|Bacilli,1ZRKX@1386|Bacillus 91061|Bacilli ET Belongs to the bacterial solute-binding protein 3 family artP - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 k141_34922_1 218284.CCDN010000007_gene3826 7.5e-42 153.0 COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HA52@91061|Bacilli,1ZCQI@1386|Bacillus 91061|Bacilli T Histidine kinase vicK - 2.7.13.3 ko:K07652 ko02020,map02020 M00459 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,PAS,PAS_9 k141_8842_2 42565.FP66_13225 1.19e-114 328.0 COG1917@1|root,COG1917@2|Bacteria,1RH1V@1224|Proteobacteria,1S3RV@1236|Gammaproteobacteria 1236|Gammaproteobacteria S conserved protein, contains double-stranded beta-helix domain - - - - - - - - - - - - Cupin_2 k141_18371_2 218284.CCDN010000010_gene4337 1.02e-12 66.6 COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,4H9R8@91061|Bacilli,1ZBD2@1386|Bacillus 91061|Bacilli P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates ecfA1 - - ko:K16786 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran k141_12525_1 1227739.Hsw_1199 1e-35 138.0 COG2124@1|root,COG2124@2|Bacteria,4NG9Z@976|Bacteroidetes,47KN0@768503|Cytophagia 976|Bacteroidetes Q Cytochrome P450 - - - - - - - - - - - - p450 k141_27657_1 1294265.JCM21738_2524 3.56e-116 334.0 COG3852@1|root,COG3852@2|Bacteria,1TRH0@1239|Firmicutes,4HD4A@91061|Bacilli,1ZARI@1386|Bacillus 91061|Bacilli T COG0642 Signal transduction histidine kinase - - 2.7.13.3 ko:K02491 ko02020,map02020 M00485 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9 k141_7550_1 218284.CCDN010000002_gene2609 9.17e-49 167.0 COG1173@1|root,COG1173@2|Bacteria,1V21B@1239|Firmicutes,4HJ5Y@91061|Bacilli,1ZFPK@1386|Bacillus 91061|Bacilli EP ABC transporter (permease) - - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 k141_8843_1 1128421.JAGA01000003_gene2926 1.26e-44 157.0 COG1994@1|root,COG1994@2|Bacteria,2NP89@2323|unclassified Bacteria 2|Bacteria S Peptidase family M50 - - - - - - - - - - - - Peptidase_M50 k141_26822_1 198467.NP92_02945 1.22e-20 92.4 COG1388@1|root,COG5632@1|root,COG1388@2|Bacteria,COG5632@2|Bacteria,1V3JT@1239|Firmicutes,4HGC1@91061|Bacilli 91061|Bacilli M Ami_2 - - 3.5.1.28 ko:K01447 - - R04112 RC00064,RC00141 ko00000,ko01000 - - - Amidase_2,Cu_amine_oxidN1,LysM k141_10025_1 1219076.N646_1533 3.51e-34 123.0 COG0084@1|root,COG0084@2|Bacteria,1MW5C@1224|Proteobacteria,1RP5T@1236|Gammaproteobacteria,1XUGD@135623|Vibrionales 135623|Vibrionales L COG0084 Mg-dependent DNase yjjV - - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase k141_10025_2 1219076.N646_1532 1.07e-282 775.0 COG1972@1|root,COG1972@2|Bacteria,1MXXX@1224|Proteobacteria,1RMBX@1236|Gammaproteobacteria,1XSKX@135623|Vibrionales 135623|Vibrionales U Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family - - - ko:K03317 - - - - ko00000 2.A.41 - - Gate,Nucleos_tra2_C,Nucleos_tra2_N k141_10025_3 1238450.VIBNISOn1_810018 4.81e-178 496.0 COG0274@1|root,COG0274@2|Bacteria,1N8AG@1224|Proteobacteria,1RPTS@1236|Gammaproteobacteria,1XTNE@135623|Vibrionales 135623|Vibrionales F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate deoC GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4 ko:K01619 ko00030,map00030 - R01066 RC00436,RC00437 ko00000,ko00001,ko01000 - - - DeoC k141_10025_4 1219076.N646_1529 3.43e-144 416.0 COG0213@1|root,COG0213@2|Bacteria,1MV3H@1224|Proteobacteria,1RPTG@1236|Gammaproteobacteria,1XSGE@135623|Vibrionales 135623|Vibrionales F The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis deoA GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009032,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0034641,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360 2.4.2.4 ko:K00758 ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219 - R01570,R02484,R08222,R08230 RC00063 ko00000,ko00001,ko01000 - - - Glycos_trans_3N,Glycos_transf_3,PYNP_C k141_2800_1 218284.CCDN010000002_gene2070 2.01e-101 317.0 COG1199@1|root,COG1199@2|Bacteria,1TPNB@1239|Firmicutes,4HD6T@91061|Bacilli,1ZAUN@1386|Bacillus 91061|Bacilli KL DEAD_2 uvrB3 - 3.1.12.1 ko:K07464 - - - - ko00000,ko01000,ko02048 - - - DEAD,DEAD_2,HBB,Helicase_C_2,PDDEXK_1 k141_31328_1 1134474.O59_003362 4.05e-31 119.0 COG0084@1|root,COG0084@2|Bacteria,1MW5C@1224|Proteobacteria,1RP5T@1236|Gammaproteobacteria,1FHDF@10|Cellvibrio 1236|Gammaproteobacteria L TatD related DNase yjjV - - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase k141_31328_2 1042377.AFPJ01000036_gene1269 2.78e-66 206.0 COG1280@1|root,COG1280@2|Bacteria,1RET0@1224|Proteobacteria,1T02W@1236|Gammaproteobacteria,46CSZ@72275|Alteromonadaceae 1236|Gammaproteobacteria E LysE type translocator - - - - - - - - - - - - LysE k141_25484_1 1116375.VEJY3_07970 4.47e-132 382.0 COG0842@1|root,COG0842@2|Bacteria,1R4QG@1224|Proteobacteria,1RTXK@1236|Gammaproteobacteria,1XTRK@135623|Vibrionales 135623|Vibrionales V ABC-type multidrug transport system, permease component - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 k141_25484_2 223926.28806708 5.97e-41 145.0 COG0842@1|root,COG0842@2|Bacteria,1MXKS@1224|Proteobacteria,1S2NW@1236|Gammaproteobacteria,1XT6T@135623|Vibrionales 135623|Vibrionales V ABC-type multidrug transport system, permease component - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 k141_23161_1 436229.JOEH01000007_gene3875 2.41e-08 63.9 COG3828@1|root,COG3828@2|Bacteria,2I49R@201174|Actinobacteria,2NF08@228398|Streptacidiphilus 201174|Actinobacteria S Ricin-type beta-trefoil - - - - - - - - - - - - RicinB_lectin_2 k141_12527_1 1294265.JCM21738_4337 3.98e-123 362.0 COG0696@1|root,COG0696@2|Bacteria,1TPM4@1239|Firmicutes,4HBTQ@91061|Bacilli,1ZAPE@1386|Bacillus 91061|Bacilli G Catalyzes the interconversion of 2-phosphoglycerate and gpmI GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030145,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0043937,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046537,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0050789,GO:0050793,GO:0051186,GO:0051188,GO:0055086,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.4.2.12 ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000 - - - Metalloenzyme,Phosphodiest,iPGM_N k141_19484_1 218284.CCDN010000001_gene574 5.69e-245 679.0 COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,4HADX@91061|Bacilli,1ZDA6@1386|Bacillus 91061|Bacilli E Belongs to the aspartokinase family lysC GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,ACT,ACT_7 k141_28974_1 1279017.AQYJ01000027_gene1663 1.36e-109 317.0 COG0521@1|root,COG0521@2|Bacteria,1R9W2@1224|Proteobacteria,1S21E@1236|Gammaproteobacteria,466IN@72275|Alteromonadaceae 1236|Gammaproteobacteria H May be involved in the biosynthesis of molybdopterin moaB GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0042802,GO:0044424,GO:0044444,GO:0044464 2.7.7.75 ko:K03638 ko00790,ko01100,map00790,map01100 - R09726 RC00002 ko00000,ko00001,ko01000 - - - MoCF_biosynth k141_28974_2 1279017.AQYJ01000027_gene1662 6.8e-86 256.0 COG0315@1|root,COG0315@2|Bacteria,1RCYZ@1224|Proteobacteria,1S3ST@1236|Gammaproteobacteria,4677K@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) moaC GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016043,GO:0016829,GO:0016849,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0022607,GO:0034214,GO:0042802,GO:0043170,GO:0043545,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0051259,GO:0061799,GO:0065003,GO:0071704,GO:0071840,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.6.1.17 ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R11372 RC03425 ko00000,ko00001,ko01000 - - - MoCF_biosynth,MoaC k141_28974_3 1279017.AQYJ01000027_gene1661 3.76e-33 116.0 COG1977@1|root,COG1977@2|Bacteria,1PC97@1224|Proteobacteria,1SX55@1236|Gammaproteobacteria,468UI@72275|Alteromonadaceae 1236|Gammaproteobacteria H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin moaD - - ko:K03636 ko04122,map04122 - - - ko00000,ko00001 - - - ThiS k141_28974_4 1279017.AQYJ01000027_gene1660 5.15e-80 240.0 COG0314@1|root,COG0314@2|Bacteria,1RGUX@1224|Proteobacteria,1S5YH@1236|Gammaproteobacteria,467A9@72275|Alteromonadaceae 1236|Gammaproteobacteria H COG0314 Molybdopterin converting factor, large subunit moaE GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016782,GO:0016783,GO:0018130,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0030366,GO:0032324,GO:0034641,GO:0042278,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.8.1.12 ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09395 RC02507 ko00000,ko00001,ko01000 - - iAPECO1_1312.APECO1_1305,iEC042_1314.EC042_0869,iEC55989_1330.EC55989_0828,iECABU_c1320.ECABU_c08270,iECED1_1282.ECED1_0750,iECIAI1_1343.ECIAI1_0820,iECIAI39_1322.ECIAI39_0761,iECNA114_1301.ECNA114_0717,iECO103_1326.ECO103_0820,iECO111_1330.ECO111_0846,iECO26_1355.ECO26_0911,iECOK1_1307.ECOK1_0787,iECP_1309.ECP_0799,iECS88_1305.ECS88_0802,iECSE_1348.ECSE_0839,iECSF_1327.ECSF_0711,iECW_1372.ECW_m0841,iEKO11_1354.EKO11_3101,iEcE24377_1341.EcE24377A_0848,iG2583_1286.G2583_1013,iLF82_1304.LF82_1369,iNRG857_1313.NRG857_03500,iSSON_1240.SSON_0764,iUMN146_1321.UM146_13720,iUTI89_1310.UTI89_C0785,iWFL_1372.ECW_m0841,ic_1306.c0867 MoaE k141_28974_5 1279017.AQYJ01000027_gene1659 4.01e-28 109.0 COG0725@1|root,COG0725@2|Bacteria,1MVNA@1224|Proteobacteria,1RN71@1236|Gammaproteobacteria,4675T@72275|Alteromonadaceae 1236|Gammaproteobacteria P molybdenum ABC transporter, periplasmic modA - - ko:K02020 ko02010,map02010 M00189 - - ko00000,ko00001,ko00002,ko02000 3.A.1.8 - - SBP_bac_11 k141_37234_1 1231057.AMGD01000012_gene1515 3.12e-10 60.1 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli,26DBZ@186818|Planococcaceae 91061|Bacilli C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively iolA - 1.2.1.18,1.2.1.27 ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 M00013 R00705,R00706,R00922,R00935 RC00004,RC02723,RC02817 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_37234_2 935836.JAEL01000050_gene5406 4.37e-139 403.0 COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,4HAPA@91061|Bacilli,1ZBBG@1386|Bacillus 91061|Bacilli C alcohol dehydrogenase adhB - 1.1.1.1,1.1.1.202 ko:K00001,ko:K00086 ko00010,ko00071,ko00350,ko00561,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00561,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R02377,R03119,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - Fe-ADH k141_36026_1 1279017.AQYJ01000028_gene2040 3.84e-63 203.0 2DBVC@1|root,2ZBAF@2|Bacteria,1PT3T@1224|Proteobacteria,1RZJK@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Psort location CytoplasmicMembrane, score 9.46 - - - - - - - - - - - - - k141_605_1 42565.FP66_07870 7.95e-108 325.0 COG3046@1|root,COG3046@2|Bacteria,1MUHX@1224|Proteobacteria,1RNUM@1236|Gammaproteobacteria,1XHMX@135619|Oceanospirillales 135619|Oceanospirillales S protein related to deoxyribodipyrimidine photolyase - - - ko:K06876 - - - - ko00000 - - - DPRP k141_10026_1 1294265.JCM21738_3759 1.7e-29 110.0 COG0860@1|root,COG0860@2|Bacteria,1TQ74@1239|Firmicutes,4HAV3@91061|Bacilli,1ZBJ8@1386|Bacillus 91061|Bacilli M n-acetylmuramoyl-L-alanine amidase cwlD GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - Amidase_3 k141_4233_16 1280001.BAOA01000261_gene2602 4.5e-73 220.0 COG0690@1|root,COG0690@2|Bacteria,1RDI9@1224|Proteobacteria,1S3PA@1236|Gammaproteobacteria,1XXD8@135623|Vibrionales 135623|Vibrionales U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation secE GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecE k141_4233_17 1219076.N646_2001 1.14e-127 363.0 COG0250@1|root,COG0250@2|Bacteria,1MU14@1224|Proteobacteria,1RMW0@1236|Gammaproteobacteria,1XTDF@135623|Vibrionales 135623|Vibrionales K Participates in transcription elongation, termination and antitermination nusG GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - ko:K02601 - - - - ko00000,ko03009,ko03021 - - - KOW,NusG k141_4233_18 1517681.HW45_27520 7.71e-93 271.0 COG0080@1|root,COG0080@2|Bacteria,1RA2M@1224|Proteobacteria,1S22R@1236|Gammaproteobacteria,1XSSH@135623|Vibrionales 135623|Vibrionales J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors rplK GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02867 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L11,Ribosomal_L11_N k141_4233_19 1238450.VIBNISOn1_950037 1.41e-151 427.0 COG0081@1|root,COG0081@2|Bacteria,1MUE6@1224|Proteobacteria,1RMDW@1236|Gammaproteobacteria,1XSM0@135623|Vibrionales 135623|Vibrionales J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release rplA GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02863 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L1 k141_4233_20 1191299.AJYX01000051_gene1316 3.19e-102 297.0 COG0244@1|root,COG0244@2|Bacteria,1RAN5@1224|Proteobacteria,1S286@1236|Gammaproteobacteria,1XTXN@135623|Vibrionales 135623|Vibrionales J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors rplJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02864 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L10 k141_4233_22 1116375.VEJY3_14765 0.0 2596.0 COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,1RMK0@1236|Gammaproteobacteria,1XUTX@135623|Vibrionales 135623|Vibrionales K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoB GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 k141_4233_23 223926.28807947 0.0 2694.0 COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,1RPYH@1236|Gammaproteobacteria,1XTEN@135623|Vibrionales 135623|Vibrionales K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoC GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 k141_4233_24 1116375.VEJY3_14755 8.56e-111 318.0 COG3160@1|root,COG3160@2|Bacteria,1RHBB@1224|Proteobacteria,1S420@1236|Gammaproteobacteria,1XWY4@135623|Vibrionales 135623|Vibrionales K Belongs to the Rsd AlgQ family rsd - - ko:K07740 - - - - ko00000 - - - Rsd_AlgQ k141_4233_25 1116375.VEJY3_14750 8.66e-182 506.0 COG2816@1|root,COG2816@2|Bacteria,1QGCX@1224|Proteobacteria,1RP0Y@1236|Gammaproteobacteria,1XV54@135623|Vibrionales 135623|Vibrionales L COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding nudC GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.6.1.22 ko:K03426 ko00760,ko01100,ko04146,map00760,map01100,map04146 - R00103,R03004,R11104 RC00002 ko00000,ko00001,ko01000 - - - NUDIX,zf-NADH-PPase k141_4233_26 1219076.N646_1992 7.47e-180 504.0 COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,1RMDH@1236|Gammaproteobacteria,1XTP5@135623|Vibrionales 135623|Vibrionales H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III hemE GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019353,GO:0019438,GO:0019752,GO:0033013,GO:0033014,GO:0033526,GO:0034641,GO:0042168,GO:0042440,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 4.1.1.37 ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03197,R04972 RC00872 ko00000,ko00001,ko00002,ko01000 - - - URO-D k141_13954_1 218284.CCDN010000001_gene462 9.54e-59 188.0 COG0588@1|root,COG0588@2|Bacteria,1TQFP@1239|Firmicutes,4HAW7@91061|Bacilli,1ZE2V@1386|Bacillus 91061|Bacilli G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate gpmA GO:0001871,GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009986,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030246,GO:0030247,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031,GO:2001065 5.4.2.11 ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - His_Phos_1 k141_27850_1 1449063.JMLS01000008_gene5164 3.04e-24 103.0 COG0583@1|root,COG0583@2|Bacteria,1V9ND@1239|Firmicutes,4HGCI@91061|Bacilli,26W0V@186822|Paenibacillaceae 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_9064_1 796606.BMMGA3_08615 4.37e-87 284.0 COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1TPYV@1239|Firmicutes,4HBER@91061|Bacilli,1ZBGN@1386|Bacillus 91061|Bacilli E Methionine synthase metH - 2.1.1.13 ko:K00548 ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230 M00017 R00946,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans k141_20796_2 218284.CCDN010000002_gene2061 1.9e-66 204.0 2CDA7@1|root,333AV@2|Bacteria,1VHFF@1239|Firmicutes,4HRPJ@91061|Bacilli,1ZHIE@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_10344_1 1379270.AUXF01000003_gene3493 3.34e-56 189.0 COG0151@1|root,COG0151@2|Bacteria,1ZSY5@142182|Gemmatimonadetes 142182|Gemmatimonadetes F Phosphoribosylglycinamide synthetase, C domain purD - 6.3.4.13 ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144 RC00090,RC00166 ko00000,ko00001,ko00002,ko01000 - - - GARS_A,GARS_C,GARS_N k141_29143_2 218284.CCDN010000001_gene965 1.72e-64 199.0 COG0781@1|root,COG0781@2|Bacteria,1VA9B@1239|Firmicutes,4HKMU@91061|Bacilli,1ZH3P@1386|Bacillus 91061|Bacilli K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons nusB - - ko:K03625 - - - - ko00000,ko03009,ko03021 - - - NusB k141_29143_3 218284.CCDN010000001_gene966 6.73e-37 132.0 COG0190@1|root,COG0190@2|Bacteria,1TP1P@1239|Firmicutes,4H9Q6@91061|Bacilli,1ZC9G@1386|Bacillus 91061|Bacilli F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate folD GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R01220,R01655 RC00202,RC00578 ko00000,ko00001,ko00002,ko01000 - - - THF_DHG_CYH,THF_DHG_CYH_C k141_36210_1 1453501.JELR01000002_gene1269 5.5e-108 319.0 COG1075@1|root,COG1075@2|Bacteria,1N2W0@1224|Proteobacteria,1S2JW@1236|Gammaproteobacteria,46749@72275|Alteromonadaceae 1236|Gammaproteobacteria S acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - - - - - - - - - - Abhydrolase_6,DUF676,Hydrolase_4,PGAP1 k141_27093_1 666686.B1NLA3E_20605 3.73e-108 318.0 COG1131@1|root,COG1131@2|Bacteria,1TQIH@1239|Firmicutes,4HCT1@91061|Bacilli,1ZCRH@1386|Bacillus 91061|Bacilli V ABC transporter CcmA5 - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_1748_1 1187848.AJYQ01000005_gene373 6.07e-23 101.0 COG0835@1|root,COG0835@2|Bacteria,1MYHY@1224|Proteobacteria,1S2TC@1236|Gammaproteobacteria,1XTG9@135623|Vibrionales 135623|Vibrionales NT Two component signalling adaptor domain VP2226 - - ko:K03408 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - CheW k141_5564_1 178306.PAE1540 1.06e-17 83.6 COG0491@1|root,arCOG00504@2157|Archaea,2XR9R@28889|Crenarchaeota 28889|Crenarchaeota S PFAM beta-lactamase domain protein - - - - - - - - - - - - Lactamase_B k141_5564_2 926562.Oweho_1921 4.9e-81 254.0 COG1600@1|root,COG1600@2|Bacteria,4NFCJ@976|Bacteroidetes,1HWPH@117743|Flavobacteriia,2PA63@246874|Cryomorphaceae 976|Bacteroidetes C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) queG - 1.17.99.6 ko:K18979 - - - - ko00000,ko01000,ko03016 - - - DUF1730,Fer4_16 k141_23389_1 218284.CCDN010000001_gene1621 1.74e-173 487.0 COG0583@1|root,COG0583@2|Bacteria,1V1MH@1239|Firmicutes,4HFVE@91061|Bacilli,1ZD99@1386|Bacillus 91061|Bacilli K Transcriptional regulator citR GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K19242 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate k141_24460_1 218284.CCDN010000002_gene2833 6.36e-106 317.0 COG0370@1|root,COG0370@2|Bacteria,1TP7E@1239|Firmicutes,4HDFJ@91061|Bacilli,1ZQG5@1386|Bacillus 91061|Bacilli P Ferrous iron transport protein B C terminus - - - ko:K04759 - - - - ko00000,ko02000 9.A.8.1 - - FeoB_C,FeoB_N,Gate k141_19730_1 1279017.AQYJ01000028_gene2464 3.19e-267 758.0 COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,1RNKN@1236|Gammaproteobacteria,463YS@72275|Alteromonadaceae 1236|Gammaproteobacteria CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit mnhA - - ko:K05565 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - DUF4040,MnhB,Proton_antipo_M,Proton_antipo_N k141_19730_2 1123053.AUDG01000048_gene1817 1.85e-106 313.0 COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,1RNUJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria V Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides macB - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_19730_3 1042377.AFPJ01000019_gene2487 4.13e-143 413.0 COG0845@1|root,COG0845@2|Bacteria,1P5GT@1224|Proteobacteria,1S7A6@1236|Gammaproteobacteria,46AKJ@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG1566 Multidrug resistance efflux pump - - - - - - - - - - - - HlyD_3,HlyD_D23 k141_19730_4 1042377.AFPJ01000019_gene2486 5.94e-100 303.0 COG0845@1|root,COG0845@2|Bacteria,1R78S@1224|Proteobacteria,1S0GJ@1236|Gammaproteobacteria,46AS9@72275|Alteromonadaceae 1236|Gammaproteobacteria M Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - ko:K02005 - - - - ko00000 - - - HlyD_3,HlyD_D23 k141_19730_5 1042377.AFPJ01000019_gene2485 2.67e-159 461.0 COG0845@1|root,COG0845@2|Bacteria,1RCT0@1224|Proteobacteria,1S3AD@1236|Gammaproteobacteria,469K1@72275|Alteromonadaceae 1236|Gammaproteobacteria M membrane-fusion protein - - - - - - - - - - - - HlyD_3,HlyD_D23 k141_19730_6 1042377.AFPJ01000019_gene2484 8.81e-222 621.0 COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,1RMBY@1236|Gammaproteobacteria,46A44@72275|Alteromonadaceae 1236|Gammaproteobacteria V COG0577 ABC-type antimicrobial peptide transport system, permease component - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD k141_19730_7 1278307.KB906967_gene2495 3.43e-18 94.7 COG5276@1|root,COG5276@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - DUF4347,LVIVD k141_19730_8 1279017.AQYJ01000027_gene1954 3.52e-106 312.0 COG0564@1|root,COG0564@2|Bacteria,1MVJ5@1224|Proteobacteria,1RN4N@1236|Gammaproteobacteria,4646S@72275|Alteromonadaceae 1236|Gammaproteobacteria J Responsible for synthesis of pseudouridine from uracil rluA - 5.4.99.28,5.4.99.29 ko:K06177 - - - - ko00000,ko01000,ko03009,ko03016 - - - PseudoU_synth_2 k141_19730_9 435908.IDSA_07110 6.11e-105 309.0 COG4221@1|root,COG4221@2|Bacteria,1MUF8@1224|Proteobacteria,1RMKM@1236|Gammaproteobacteria,2QFPG@267893|Idiomarinaceae 1236|Gammaproteobacteria S KR domain - - - - - - - - - - - - adh_short k141_19730_10 1453501.JELR01000002_gene452 0.0 1070.0 COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,1RPZD@1236|Gammaproteobacteria,469NG@72275|Alteromonadaceae 1236|Gammaproteobacteria K Ribonuclease R winged-helix domain - - - ko:K12573 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03016,ko03019 - - - HTH_12,OB_RNB,RNB,S1 k141_19730_12 1286632.P278_31310 5.28e-307 854.0 28HMZ@1|root,2Z7WD@2|Bacteria,4P095@976|Bacteroidetes 2|Bacteria S Protein of unknown function (DUF3604) - - - - - - - - - - - - DUF3604 k141_7718_2 218284.CCDN010000001_gene1532 2.08e-15 75.1 COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,4H9ZF@91061|Bacilli,1ZB20@1386|Bacillus 91061|Bacilli C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate glpK GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 - R00847 RC00002,RC00017 ko00000,ko00001,ko01000,ko04147 - - - FGGY_C,FGGY_N k141_35220_2 153948.NAL212_1704 5.3e-14 78.6 COG2267@1|root,COG2267@2|Bacteria,1PE8E@1224|Proteobacteria,2W9K3@28216|Betaproteobacteria,373RZ@32003|Nitrosomonadales 28216|Betaproteobacteria I alpha/beta hydrolase fold - - - - - - - - - - - - Abhydrolase_1 k141_12762_1 218284.CCDN010000007_gene3919 2.24e-36 129.0 COG1595@1|root,COG1595@2|Bacteria,1UIX6@1239|Firmicutes,4ISVD@91061|Bacilli,1ZS74@1386|Bacillus 91061|Bacilli K Sigma-70, region 4 - - - - - - - - - - - - Sigma70_r4,Sigma70_r4_2 k141_4234_1 218284.CCDN010000002_gene2326 7.02e-72 223.0 28XAZ@1|root,2ZJ8Y@2|Bacteria,1V2XT@1239|Firmicutes,4HGD4@91061|Bacilli,1ZG66@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_4234_2 218284.CCDN010000002_gene2327 2.46e-15 74.3 29UJD@1|root,30FWM@2|Bacteria,1V548@1239|Firmicutes,4HIC6@91061|Bacilli,1ZGAZ@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_16109_1 1294265.JCM21738_4037 1.47e-196 550.0 COG0771@1|root,COG0771@2|Bacteria,1TQ3P@1239|Firmicutes,4HA5P@91061|Bacilli,1ZARV@1386|Bacillus 91061|Bacilli M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) murD - 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase_C,Mur_ligase_M k141_23390_1 485916.Dtox_1746 2.5e-30 125.0 COG1196@1|root,COG4717@1|root,COG1196@2|Bacteria,COG4717@2|Bacteria,1TQP3@1239|Firmicutes 1239|Firmicutes D Psort location Cytoplasmic, score yhaN - - - - - - - - - - - AAA_27 k141_5592_2 218284.CCDN010000001_gene1489 5.39e-70 230.0 COG0188@1|root,COG0188@2|Bacteria,1TRE7@1239|Firmicutes,4HAQB@91061|Bacilli,1ZBCI@1386|Bacillus 91061|Bacilli L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K02621 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseA_C,DNA_topoisoIV k141_11524_1 223926.28806311 9.91e-119 339.0 COG1451@1|root,COG1451@2|Bacteria,1RDJ9@1224|Proteobacteria,1S45M@1236|Gammaproteobacteria,1XTK3@135623|Vibrionales 135623|Vibrionales S Metal-dependent hydrolase ygjP - - ko:K07043 - - - - ko00000 - - - DUF45 k141_11524_2 1219076.N646_0355 4.19e-48 153.0 COG0695@1|root,COG0695@2|Bacteria,1N12W@1224|Proteobacteria,1SB6J@1236|Gammaproteobacteria,1XYAR@135623|Vibrionales 135623|Vibrionales O COG0695 Glutaredoxin and related proteins - - - - - - - - - - - - Glutaredoxin k141_11524_3 1116375.VEJY3_06395 2.11e-192 535.0 COG0583@1|root,COG0583@2|Bacteria,1NUAB@1224|Proteobacteria,1RNYQ@1236|Gammaproteobacteria,1XSF5@135623|Vibrionales 135623|Vibrionales K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_11524_4 1116375.VEJY3_06390 2.4e-262 722.0 COG0477@1|root,COG2814@2|Bacteria,1MWFH@1224|Proteobacteria,1RPAT@1236|Gammaproteobacteria,1XTE4@135623|Vibrionales 135623|Vibrionales EGP of the major facilitator superfamily - - - - - - - - - - - - MFS_1 k141_11524_5 1116375.VEJY3_06385 1.42e-127 363.0 COG3310@1|root,COG3310@2|Bacteria,1RDE0@1224|Proteobacteria,1S3X6@1236|Gammaproteobacteria,1XU3W@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria - - - ko:K09941 - - - - ko00000 - - - DUF1415 k141_18676_2 1347369.CCAD010000063_gene3986 0.000445 41.6 COG0773@1|root,COG0773@2|Bacteria,1TQ5H@1239|Firmicutes,4HAR4@91061|Bacilli,1ZB5U@1386|Bacillus 91061|Bacilli M Belongs to the MurCDEF family murC - 6.3.2.8 ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M k141_23423_1 1116369.KB890024_gene2802 2.82e-49 166.0 28PP7@1|root,2ZCBP@2|Bacteria,1NEUP@1224|Proteobacteria,2UGQR@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_23423_2 1453501.JELR01000002_gene1504 1.13e-184 519.0 COG2267@1|root,COG2267@2|Bacteria,1RAQZ@1224|Proteobacteria,1S2YX@1236|Gammaproteobacteria,467BE@72275|Alteromonadaceae 1236|Gammaproteobacteria I Serine aminopeptidase, S33 pldB - 3.1.1.5 ko:K01048 ko00564,map00564 - - - ko00000,ko00001,ko01000 - - - Hydrolase_4 k141_13990_1 218284.CCDN010000001_gene1302 9.33e-123 363.0 COG0477@1|root,COG2814@2|Bacteria,1VSW8@1239|Firmicutes,4HUQC@91061|Bacilli,1ZAS8@1386|Bacillus 91061|Bacilli EGP the major facilitator superfamily mdr GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - - - - - - - - - - MFS_1 k141_1762_1 1042377.AFPJ01000022_gene1302 1.25e-117 361.0 COG1251@1|root,COG1251@2|Bacteria,1MW58@1224|Proteobacteria,1RNGY@1236|Gammaproteobacteria,4656K@72275|Alteromonadaceae 1236|Gammaproteobacteria C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family nirB - 1.7.1.15 ko:K00362 ko00910,ko01120,map00910,map01120 M00530 R00787 RC00176 ko00000,ko00001,ko00002,ko01000 - - - Fer2_BFD,NIR_SIR,NIR_SIR_ferr,Pyr_redox_2 k141_14854_1 218284.CCDN010000006_gene3655 1.45e-159 473.0 COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,4HAW9@91061|Bacilli,1ZARC@1386|Bacillus 91061|Bacilli L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate uvrA - - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran k141_6692_1 218284.CCDN010000002_gene1980 1.03e-113 327.0 COG4843@1|root,COG4843@2|Bacteria,1V14J@1239|Firmicutes,4HCBK@91061|Bacilli,1ZBPZ@1386|Bacillus 91061|Bacilli S UPF0316 protein yebE - - - - - - - - - - - DUF2179 k141_6692_2 218284.CCDN010000002_gene1981 2.89e-37 125.0 2BXZ7@1|root,330R4@2|Bacteria,1VF1V@1239|Firmicutes,4HNQ7@91061|Bacilli,1ZR8R@1386|Bacillus 91061|Bacilli S NETI protein - - - - - - - - - - - - NETI k141_19757_1 342610.Patl_2717 7.62e-33 124.0 COG2301@1|root,COG2301@2|Bacteria,1MW0A@1224|Proteobacteria,1RNEJ@1236|Gammaproteobacteria,2Q4XY@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria H Belongs to the HpcH HpaI aldolase family mcl1 - 4.1.3.25,4.1.3.34 ko:K01644,ko:K18292 ko00660,ko01100,ko02020,map00660,map01100,map02020 - R00237,R00362 RC00067,RC00502,RC01118,RC01205 ko00000,ko00001,ko01000 - - - HpcH_HpaI k141_19757_2 1042377.AFPJ01000008_gene2018 5.43e-200 555.0 COG0726@1|root,COG0726@2|Bacteria,1MV3V@1224|Proteobacteria,1RPKM@1236|Gammaproteobacteria,469ZP@72275|Alteromonadaceae 1236|Gammaproteobacteria G Polysaccharide deacetylase - - 3.5.1.104 ko:K22278 - - - - ko00000,ko01000 - - - Polysacc_deac_1 k141_19757_3 1042377.AFPJ01000008_gene2017 6.01e-121 350.0 COG1028@1|root,COG1028@2|Bacteria,1MVQW@1224|Proteobacteria,1RNY1@1236|Gammaproteobacteria,46A35@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ KR domain - - 1.1.1.304,1.1.1.76 ko:K03366 ko00650,map00650 - R02855,R02946,R03707,R09078,R10505 RC00205,RC00525 ko00000,ko00001,ko01000 - - - adh_short_C2 k141_32669_2 492774.JQMB01000010_gene4663 5.12e-74 231.0 COG0693@1|root,COG0693@2|Bacteria,1MVTT@1224|Proteobacteria,2TT0C@28211|Alphaproteobacteria,4B76C@82115|Rhizobiaceae 28211|Alphaproteobacteria S DJ-1/PfpI family - - - - - - - - - - - - DJ-1_PfpI k141_9088_2 218284.CCDN010000001_gene1188 5.82e-33 119.0 2CFTY@1|root,336V6@2|Bacteria,1VH1W@1239|Firmicutes,4HQI3@91061|Bacilli,1ZH6G@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_13991_1 218284.CCDN010000006_gene3717 1.43e-94 282.0 COG1227@1|root,COG1227@2|Bacteria,1TPH6@1239|Firmicutes,4H9T8@91061|Bacilli,1ZBEH@1386|Bacillus 91061|Bacilli C Inorganic pyrophosphatase ppaC GO:0003674,GO:0003824,GO:0004427,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0044237,GO:0044424,GO:0044464 3.6.1.1 ko:K15986 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - DHH,DHHA2 k141_37444_1 1042377.AFPJ01000010_gene1440 1.36e-113 336.0 COG0676@1|root,COG0676@2|Bacteria,1Q7VN@1224|Proteobacteria,1RQK0@1236|Gammaproteobacteria,466U8@72275|Alteromonadaceae 1236|Gammaproteobacteria G Belongs to the glucose-6-phosphate 1-epimerase family yeaD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716 5.1.3.15 ko:K01792 ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130 - R02739 RC00563 ko00000,ko00001,ko01000 - - - Aldose_epim k141_37444_2 745014.OMB55_00007740 5.54e-48 166.0 COG2084@1|root,COG3791@1|root,COG2084@2|Bacteria,COG3791@2|Bacteria,1MUGU@1224|Proteobacteria,1RQ2D@1236|Gammaproteobacteria,1J4JN@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases garR - 1.1.1.31,1.1.1.60 ko:K00020,ko:K00042 ko00280,ko00630,ko01100,map00280,map00630,map01100 - R01745,R01747,R05066 RC00099 ko00000,ko00001,ko01000 - - - NAD_binding_11,NAD_binding_2 k141_22061_1 247633.GP2143_01970 8.98e-155 460.0 COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,1RNB7@1236|Gammaproteobacteria 1236|Gammaproteobacteria S metal-dependent hydrolase with the TIM-barrel fold - - - - - - - - - - - - Amidohydro_3 k141_1763_1 1279017.AQYJ01000027_gene1665 8.64e-58 187.0 COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,1RR68@1236|Gammaproteobacteria,464NZ@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate moaA GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016829,GO:0016830,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0061798,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.22 ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09394 RC03420 ko00000,ko00001,ko01000 - - iSbBS512_1146.SbBS512_E2571,ic_1306.c0862 Fer4_12,Mob_synth_C,Radical_SAM k141_1763_2 639030.JHVA01000001_gene3937 5.85e-06 49.3 COG0746@1|root,COG0746@2|Bacteria,3Y5GH@57723|Acidobacteria,2JJWH@204432|Acidobacteriia 204432|Acidobacteriia H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor mobA - 2.7.7.77 ko:K03752 ko00790,ko01100,map00790,map01100 - R11581 - ko00000,ko00001,ko01000 - - - NTP_transf_3 k141_17289_1 637390.AFOH01000006_gene973 7.7e-67 220.0 COG2826@1|root,COG2826@2|Bacteria,1PP49@1224|Proteobacteria,1RN7B@1236|Gammaproteobacteria,2NDSU@225057|Acidithiobacillales 225057|Acidithiobacillales L COG2826 Transposase and inactivated derivatives, IS30 family - - - - - - - - - - - - rve k141_27874_1 935836.JAEL01000007_gene2897 8.74e-139 409.0 COG1620@1|root,COG1620@2|Bacteria,1TQNM@1239|Firmicutes,4HAF3@91061|Bacilli,1ZC0U@1386|Bacillus 91061|Bacilli C L-lactate permease - - - ko:K03303 - - - - ko00000,ko02000 2.A.14 - - Lactate_perm k141_27130_1 218284.CCDN010000007_gene3982 2.89e-42 142.0 COG1246@1|root,COG1246@2|Bacteria,1U9KN@1239|Firmicutes,4IN7D@91061|Bacilli,1ZJ7M@1386|Bacillus 91061|Bacilli E Belongs to the acetyltransferase family. ArgA subfamily - - - - - - - - - - - - Acetyltransf_1 k141_23424_2 1453501.JELR01000002_gene1231 2.23e-52 168.0 COG2363@1|root,COG2363@2|Bacteria,1MZX3@1224|Proteobacteria,1SCNB@1236|Gammaproteobacteria,468G6@72275|Alteromonadaceae 1236|Gammaproteobacteria S small membrane protein ygdD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - DUF423 k141_19758_3 218284.CCDN010000001_gene1917 6.11e-08 53.1 COG3190@1|root,COG3190@2|Bacteria,1VGFI@1239|Firmicutes,4HJJQ@91061|Bacilli,1ZETY@1386|Bacillus 91061|Bacilli N Flagellar biosynthesis protein, FliO fliZ - - ko:K02418 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - FliO k141_14855_2 218284.CCDN010000001_gene107 4.63e-65 209.0 COG3314@1|root,COG3314@2|Bacteria,1TR0V@1239|Firmicutes,4HB55@91061|Bacilli,1ZCCT@1386|Bacillus 91061|Bacilli S Sporulation integral membrane protein YlbJ ylbJ - - - - - - - - - - - Gate k141_18679_1 218284.CCDN010000001_gene1575 9.45e-122 353.0 COG0516@1|root,COG0516@2|Bacteria,1TNYF@1239|Firmicutes,4HA55@91061|Bacilli,1ZCDA@1386|Bacillus 91061|Bacilli F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides guaC - 1.7.1.7 ko:K00364 ko00230,map00230 - R01134 RC00457 ko00000,ko00001,ko01000 - - iSB619.SA_RS06660 IMPDH k141_6694_1 225937.HP15_4108 5.8e-55 185.0 COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,1RVZ6@1236|Gammaproteobacteria,466FT@72275|Alteromonadaceae 1236|Gammaproteobacteria J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine - - 2.7.7.87 ko:K07566 - - R10463 RC00745 ko00000,ko01000,ko03009,ko03016 - - - SUA5,Sua5_yciO_yrdC k141_1764_1 935836.JAEL01000024_gene2433 1.47e-67 217.0 COG4302@1|root,COG4302@2|Bacteria,1TSZM@1239|Firmicutes,4HDFG@91061|Bacilli,1ZCZI@1386|Bacillus 91061|Bacilli E Ethanolamine ammonia-lyase light chain (EutC) eutC GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0009350,GO:0019842,GO:0031419,GO:0032991,GO:0036094,GO:0044424,GO:0044464,GO:0046906,GO:0048037,GO:0097159,GO:1901363,GO:1902494 4.3.1.7 ko:K03736 ko00564,ko01100,map00564,map01100 - R00749 RC00370 ko00000,ko00001,ko01000 - - - EutC k141_23425_1 1385511.N783_13045 7.71e-171 483.0 COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,1TPE2@1239|Firmicutes,4H9WH@91061|Bacilli,2Y9SH@289201|Pontibacillus 91061|Bacilli P Rhodanese Homology Domain - - - - - - - - - - - - Lactamase_B,Rhodanese k141_20817_1 411467.BACCAP_04744 9.22e-17 79.3 COG0449@1|root,COG0449@2|Bacteria,1TPGU@1239|Firmicutes,248F8@186801|Clostridia,267VP@186813|unclassified Clostridiales 186801|Clostridia M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source glmS - 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 - R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 - - - GATase_6,SIS k141_20817_2 566466.NOR53_2347 1.33e-15 78.6 COG2197@1|root,COG2197@2|Bacteria,1RDUR@1224|Proteobacteria,1S9GG@1236|Gammaproteobacteria 1236|Gammaproteobacteria KT helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE k141_5595_1 1453501.JELR01000001_gene3106 4.99e-85 271.0 COG4773@1|root,COG4773@2|Bacteria,1QTXJ@1224|Proteobacteria,1T2NX@1236|Gammaproteobacteria,46D3S@72275|Alteromonadaceae 1236|Gammaproteobacteria P TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_19760_1 218284.CCDN010000001_gene1045 4.9e-70 217.0 COG1191@1|root,COG1191@2|Bacteria,1TP3Q@1239|Firmicutes,4HC42@91061|Bacilli,1ZANZ@1386|Bacillus 91061|Bacilli K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released sigF - - ko:K03091 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r3,Sigma70_r4 k141_14856_1 406124.ACPC01000017_gene673 9.9e-84 256.0 COG0631@1|root,COG0631@2|Bacteria,1TSV6@1239|Firmicutes,4HAP5@91061|Bacilli,1ZDPD@1386|Bacillus 91061|Bacilli T Protein phosphatase 2C - - - - - - - - - - - - PP2C_2 k141_14856_2 981383.AEWH01000019_gene3455 1.98e-25 102.0 COG3173@1|root,COG3173@2|Bacteria,1UZ6J@1239|Firmicutes,4HEYZ@91061|Bacilli 91061|Bacilli S Phosphotransferase enzyme family - - - - - - - - - - - - APH k141_29165_1 596320.NEIFL0001_1851 7.45e-29 112.0 COG4969@1|root,COG4969@2|Bacteria,1N7EQ@1224|Proteobacteria,2VVSJ@28216|Betaproteobacteria 28216|Betaproteobacteria NU Belongs to the N-Me-Phe pilin family pilE - - ko:K02650 ko02020,map02020 - - - ko00000,ko00001,ko02035,ko02044 3.A.15.2 - - N_methyl,Pilin k141_22063_1 1294265.JCM21738_4212 7.23e-116 340.0 COG4114@1|root,COG4114@2|Bacteria,1V28K@1239|Firmicutes,4HGQ8@91061|Bacilli,1ZB7Y@1386|Bacillus 91061|Bacilli S FhuF 2Fe-2S C-terminal domain - - - - - - - - - - - - FhuF,FhuF_C k141_23426_1 574966.KB898651_gene2016 9.07e-120 363.0 COG4773@1|root,COG4773@2|Bacteria,1MW5E@1224|Proteobacteria,1RMBD@1236|Gammaproteobacteria,1XJW9@135619|Oceanospirillales 135619|Oceanospirillales P COG4773 Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid - - - ko:K16088 - - - - ko00000,ko02000 1.B.14.1.10,1.B.14.1.3,1.B.14.1.8 - - Plug,TonB_dep_Rec k141_16289_2 866895.HBHAL_3208 5.89e-14 69.7 COG0454@1|root,COG0456@2|Bacteria,1U521@1239|Firmicutes,4HBEJ@91061|Bacilli,3NFRE@45667|Halobacillus 91061|Bacilli K Acetyltransferase (GNAT) family ykwB - - - - - - - - - - - Acetyltransf_1 k141_999_1 218284.CCDN010000002_gene2602 2.73e-141 406.0 COG1063@1|root,COG1063@2|Bacteria,1TPIW@1239|Firmicutes,4HB2G@91061|Bacilli,1ZB9D@1386|Bacillus 91061|Bacilli E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases adhB - 1.1.1.1,1.1.1.284 ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 - R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_N_assoc,ADH_zinc_N k141_24665_1 218284.CCDN010000002_gene2724 1.19e-97 300.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1TQ85@1239|Firmicutes,4HAC0@91061|Bacilli,1ZR0Z@1386|Bacillus 91061|Bacilli EU Dienelactone hydrolase family - - - - - - - - - - - - PD40,Peptidase_S9,Peptidase_S9_N k141_1903_1 545693.BMQ_1906 4.72e-85 271.0 COG0642@1|root,COG2205@2|Bacteria,1V10X@1239|Firmicutes,4HAU7@91061|Bacilli,1ZB6A@1386|Bacillus 91061|Bacilli T Histidine kinase - - - - - - - - - - - - HAMP,HATPase_c,HisKA k141_22343_1 1116375.VEJY3_13040 4.18e-183 512.0 COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,1RN90@1236|Gammaproteobacteria,1XTYX@135623|Vibrionales 135623|Vibrionales NOU Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue pilD - 3.4.23.43 ko:K02654 - M00331 - - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 3.A.15.2 - - DiS_P_DiS,Peptidase_A24 k141_22343_2 223926.28807525 1.17e-124 357.0 COG0237@1|root,COG0237@2|Bacteria,1RCXT@1224|Proteobacteria,1S3NR@1236|Gammaproteobacteria,1XW2K@135623|Vibrionales 135623|Vibrionales F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A coaE GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 ko:K00859 ko00770,ko01100,map00770,map01100 M00120 R00130 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - CoaE k141_22343_3 1116375.VEJY3_13050 2.2e-168 471.0 COG4582@1|root,COG4582@2|Bacteria,1MW69@1224|Proteobacteria,1RNPD@1236|Gammaproteobacteria,1XT60@135623|Vibrionales 135623|Vibrionales D Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity zapD GO:0000003,GO:0000910,GO:0005575,GO:0005623,GO:0007049,GO:0008150,GO:0009987,GO:0019954,GO:0022402,GO:0022414,GO:0032153,GO:0032505,GO:0043093,GO:0044464,GO:0051301 - ko:K18778 - - - - ko00000,ko03036 - - - ZapD k141_35467_2 1116375.VEJY3_23416 1.26e-186 520.0 COG0348@1|root,COG0348@2|Bacteria,1MWR5@1224|Proteobacteria,1RQ1I@1236|Gammaproteobacteria,1XTU5@135623|Vibrionales 135623|Vibrionales C Quinol dehydrogenase napH - - ko:K02574 - - - - ko00000 - - - Fer4_5,Fer4_6,Fer4_9 k141_35467_3 1116375.VEJY3_23411 7.27e-266 730.0 COG2223@1|root,COG2223@2|Bacteria,1MW71@1224|Proteobacteria,1RN10@1236|Gammaproteobacteria,1XSI0@135623|Vibrionales 135623|Vibrionales P COG0477 Permeases of the major facilitator superfamily - - - - - - - - - - - - MFS_1 k141_35467_4 223926.28809882 4.8e-226 628.0 COG1566@1|root,COG1566@2|Bacteria,1NAMI@1224|Proteobacteria,1RP4N@1236|Gammaproteobacteria,1XUYE@135623|Vibrionales 135623|Vibrionales V multidrug resistance efflux pump - - - - - - - - - - - - Biotin_lipoyl_2,HlyD_D23 k141_35467_5 223926.28809881 1.06e-71 217.0 2CIMK@1|root,32S89@2|Bacteria,1N0NJ@1224|Proteobacteria,1S9BM@1236|Gammaproteobacteria,1XXIK@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF3302) yiaW - - - - - - - - - - - DUF3302 k141_35467_6 1280001.BAOA01000076_gene3260 7.17e-162 459.0 COG0697@1|root,COG0697@2|Bacteria,1R4G2@1224|Proteobacteria,1S08Y@1236|Gammaproteobacteria,1XUQP@135623|Vibrionales 135623|Vibrionales EG EamA-like transporter family - - - - - - - - - - - - EamA k141_19981_1 935836.JAEL01000010_gene3771 2.97e-14 72.8 COG1595@1|root,COG1595@2|Bacteria,1U9I0@1239|Firmicutes,4IJNF@91061|Bacilli,1ZC9D@1386|Bacillus 91061|Bacilli K Domain of unknown function (DUF4179) - - - - - - - - - - - - DUF4179,Sigma70_r4,Sigma70_r4_2,zf-HC2 k141_1012_1 1121938.AUDY01000011_gene595 4.33e-109 327.0 COG0438@1|root,COG0438@2|Bacteria,1UYV4@1239|Firmicutes,4HE87@91061|Bacilli 91061|Bacilli M Glycosyltransferase Family 4 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 k141_20957_1 218284.CCDN010000003_gene2972 6.07e-244 684.0 COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1TPA1@1239|Firmicutes,4H9VC@91061|Bacilli,1ZASP@1386|Bacillus 91061|Bacilli J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation metG GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1g,tRNA_bind k141_28005_1 1121015.N789_12665 9.13e-23 113.0 COG4447@1|root,COG4447@2|Bacteria,1NRDC@1224|Proteobacteria,1S0E3@1236|Gammaproteobacteria,1X7BC@135614|Xanthomonadales 135614|Xanthomonadales S cellulose binding - - - - - - - - - - - - - k141_10459_1 1294265.JCM21738_3954 4.28e-35 128.0 COG0860@1|root,COG0860@2|Bacteria,1TSFS@1239|Firmicutes,4HACZ@91061|Bacilli,1ZAV0@1386|Bacillus 91061|Bacilli M stage II sporulation protein P spoIIP - - ko:K06385 - - - - ko00000 - - - SpoIIP k141_10459_2 1294265.JCM21738_3955 7.2e-38 135.0 COG0680@1|root,COG0680@2|Bacteria,1TPFY@1239|Firmicutes,4HAGH@91061|Bacilli,1ZC4A@1386|Bacillus 91061|Bacilli C Initiates the rapid degradation of small, acid-soluble proteins during spore germination gpr GO:0000003,GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019954,GO:0030436,GO:0032502,GO:0043170,GO:0043934,GO:0044238,GO:0071704,GO:0140096,GO:1901564 3.4.24.78 ko:K06012 - - - - ko00000,ko01000,ko01002 - - - Peptidase_A25 k141_19010_1 935836.JAEL01000024_gene2431 5.36e-36 133.0 COG4819@1|root,COG4819@2|Bacteria,1TQ6T@1239|Firmicutes,4HAEM@91061|Bacilli,1ZDKX@1386|Bacillus 91061|Bacilli E Ethanolamine utilisation protein EutA eutA - - ko:K04019 ko00564,ko01100,map00564,map01100 - R00749 RC00370 ko00000,ko00001 - - - EutA k141_19010_2 1340434.AXVA01000017_gene4142 2.29e-77 243.0 COG4303@1|root,COG4303@2|Bacteria,1TP15@1239|Firmicutes,4HBSM@91061|Bacilli,1ZD42@1386|Bacillus 91061|Bacilli E Ethanolamine ammonia lyase large subunit (EutB) eutB - 4.3.1.7 ko:K03735,ko:K16785 ko00564,ko01100,ko02010,map00564,map01100,map02010 M00582 R00749 RC00370 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - EutB k141_1013_1 1117379.BABA_19016 1.18e-35 125.0 COG5546@1|root,COG5546@2|Bacteria,1VGGV@1239|Firmicutes,4HPNN@91061|Bacilli,1ZIFW@1386|Bacillus 91061|Bacilli S COG5546 Small integral membrane protein - - - - - - - - - - - - Phage_holin_1 k141_26013_1 218284.CCDN010000001_gene157 9.32e-48 156.0 COG0242@1|root,COG0242@2|Bacteria,1V70B@1239|Firmicutes,4HH0G@91061|Bacilli,1ZB0K@1386|Bacillus 91061|Bacilli J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions def GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 ko:K01462 - - - - ko00000,ko01000 - - - Pep_deformylase k141_26013_2 935836.JAEL01000127_gene3145 6.58e-17 79.3 COG0497@1|root,COG0497@2|Bacteria,1V4G3@1239|Firmicutes,4HHDM@91061|Bacilli,1ZH4B@1386|Bacillus 91061|Bacilli L Putative cell-wall binding lipoprotein ykyA - - - - - - - - - - - YkyA k141_36369_1 218284.CCDN010000002_gene2870 1.47e-126 374.0 COG3290@1|root,COG3290@2|Bacteria,1TQJR@1239|Firmicutes,4H9Q0@91061|Bacilli,1ZBHV@1386|Bacillus 91061|Bacilli T Signal transduction histidine kinase regulating citrate malate metabolism citS - 2.7.13.3 ko:K11637 ko02020,map02020 M00487 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,PAS,PAS_8,PAS_9,SPOB_a,sCache_3_2 k141_29373_1 218284.CCDN010000001_gene1040 5.95e-157 443.0 COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,4HABP@91061|Bacilli,1ZBKZ@1386|Bacillus 91061|Bacilli F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate punA - 2.4.2.1,2.4.2.28 ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 M00034 R01402,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244 RC00033,RC00063,RC00122,RC02819 ko00000,ko00001,ko00002,ko01000 - - - PNP_UDP_1 k141_1918_1 218284.CCDN010000001_gene1099 1.58e-185 518.0 28IBV@1|root,2Z8EA@2|Bacteria,1TPCJ@1239|Firmicutes,4HB3C@91061|Bacilli,1ZBT4@1386|Bacillus 91061|Bacilli S YIEGIA protein yphB - - ko:K05739 - - - - ko00000 - - - YIEGIA k141_6989_1 218284.CCDN010000002_gene2181 6.52e-42 153.0 COG1502@1|root,COG1502@2|Bacteria,1VSU5@1239|Firmicutes,4HTP4@91061|Bacilli,1ZJTB@1386|Bacillus 91061|Bacilli I Lamin Tail Domain - - - - - - - - - - - - LTD,PLDc_2 k141_6989_2 218284.CCDN010000002_gene2173 2.67e-67 208.0 COG2197@1|root,COG2197@2|Bacteria,1TQ1U@1239|Firmicutes,4HA4B@91061|Bacilli,1ZAT4@1386|Bacillus 91061|Bacilli KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain vraR - - ko:K07694,ko:K11618 ko02020,map02020 M00480,M00481,M00754 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg k141_23724_1 1042377.AFPJ01000037_gene2876 9.69e-63 205.0 28RR1@1|root,2ZE3K@2|Bacteria,1P7PJ@1224|Proteobacteria,1SUUS@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain present in PSD-95, Dlg, and ZO-1/2. - - - - - - - - - - - - PDZ_2 k141_19011_1 218284.CCDN010000005_gene3385 6.31e-118 346.0 COG0520@1|root,COG0520@2|Bacteria,1TQ1W@1239|Firmicutes,4HA6Z@91061|Bacilli,1ZB79@1386|Bacillus 91061|Bacilli E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine sufS - 2.8.1.7,4.4.1.16 ko:K11717 ko00450,ko01100,map00450,map01100 - R03599,R11528 RC00961,RC01789,RC02313 ko00000,ko00001,ko01000 - - - Aminotran_5 k141_26014_1 42565.FP66_11105 1.88e-111 332.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1XIXB@135619|Oceanospirillales 135619|Oceanospirillales T With GlrK is part of a two-component signal transduction system regulating glmY - - - ko:K07715 ko02020,ko02024,map02020,map02024 M00502 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat k141_1014_1 1392540.P256_00912 1.49e-09 58.5 COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,1RMD2@1236|Gammaproteobacteria,3NK8U@468|Moraxellaceae 1236|Gammaproteobacteria E Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate betA GO:0001505,GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0006113,GO:0006575,GO:0006577,GO:0006578,GO:0006807,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0008812,GO:0009058,GO:0009628,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0019285,GO:0019695,GO:0031455,GO:0031456,GO:0034641,GO:0042133,GO:0042398,GO:0044237,GO:0044249,GO:0044271,GO:0050896,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 1.1.99.1 ko:K00108 ko00260,ko01100,map00260,map01100 M00555 R01025 RC00087 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_1679,iECDH10B_1368.ECDH10B_0298,iECDH1ME8569_1439.ECDH1ME8569_0299,iECH74115_1262.ECH74115_0373,iECOK1_1307.ECOK1_0305,iECS88_1305.ECS88_0319,iECSP_1301.ECSP_0366,iECs_1301.ECs0357,iEcDH1_1363.EcDH1_3295,iEcolC_1368.EcolC_3312,iG2583_1286.G2583_0415,iJN746.PP_5064,iJO1366.b0311,iUMN146_1321.UM146_15745,iY75_1357.Y75_RS01610,iZ_1308.Z0398 GMC_oxred_C,GMC_oxred_N k141_1014_2 1380387.JADM01000001_gene376 9.82e-62 209.0 COG1292@1|root,COG1292@2|Bacteria,1MV0K@1224|Proteobacteria,1RP3E@1236|Gammaproteobacteria,1XN46@135619|Oceanospirillales 135619|Oceanospirillales M BCCT, betaine/carnitine/choline family transporter - - - ko:K02168 - - - - ko00000,ko02000 2.A.15.1.3,2.A.15.1.4 - - BCCT k141_4388_1 218284.CCDN010000007_gene3794 1.32e-87 263.0 COG0706@1|root,COG0706@2|Bacteria,1TQ0J@1239|Firmicutes,4HB3J@91061|Bacilli,1ZBYD@1386|Bacillus 91061|Bacilli U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins yidC GO:0005575,GO:0008150,GO:0009653,GO:0009987,GO:0016020,GO:0030154,GO:0030435,GO:0032502,GO:0043934,GO:0048646,GO:0048856,GO:0048869 - ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 - - 60KD_IMP k141_1919_1 498211.CJA_1289 4.3e-20 88.6 COG0726@1|root,COG0726@2|Bacteria,1RBMV@1224|Proteobacteria,1S27I@1236|Gammaproteobacteria,1FG2P@10|Cellvibrio 1236|Gammaproteobacteria G Polysaccharide deacetylase - - - - - - - - - - - - Polysacc_deac_1 k141_23725_1 882.DVU_3240 6.47e-10 65.5 COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,42P5W@68525|delta/epsilon subdivisions,2WMA6@28221|Deltaproteobacteria,2M8GP@213115|Desulfovibrionales 28221|Deltaproteobacteria M PFAM Peptidase M23 - - - - - - - - - - - - Peptidase_M23 k141_22388_2 674977.VMC_33260 4.43e-149 421.0 COG0602@1|root,COG0602@2|Bacteria,1MUJ2@1224|Proteobacteria,1RNQZ@1236|Gammaproteobacteria,1XUXZ@135623|Vibrionales 135623|Vibrionales H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds queE - 4.3.99.3 ko:K10026 ko00790,ko01100,map00790,map01100 - R10002 RC02989 ko00000,ko00001,ko01000,ko03016 - - - Fer4_14,Radical_SAM k141_22388_3 1116375.VEJY3_07765 2.05e-161 452.0 COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,1RMG9@1236|Gammaproteobacteria,1XTZ0@135623|Vibrionales 135623|Vibrionales F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) queC - 6.3.4.20 ko:K06920 ko00790,ko01100,map00790,map01100 - R09978 RC00959 ko00000,ko00001,ko01000,ko03016 - - - QueC k141_3196_4 1279017.AQYJ01000027_gene1958 1.78e-124 360.0 COG1385@1|root,COG1385@2|Bacteria,1MXCU@1224|Proteobacteria,1RPBN@1236|Gammaproteobacteria,466M1@72275|Alteromonadaceae 1236|Gammaproteobacteria J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit rsmE GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.193 ko:K09761 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_RNA k141_32895_1 1116375.VEJY3_19011 5.03e-123 380.0 COG4192@1|root,COG4251@1|root,COG4192@2|Bacteria,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,1T1YP@1236|Gammaproteobacteria,1XSNQ@135623|Vibrionales 135623|Vibrionales T COG0642 Signal transduction histidine kinase torS - 2.7.13.3 ko:K07647 ko02020,map02020 M00455 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - 4HB_MCP_1,HATPase_c,HisKA,Hpt,Response_reg k141_32895_2 1116375.VEJY3_19006 1.08e-196 550.0 COG1879@1|root,COG1879@2|Bacteria,1MXQN@1224|Proteobacteria,1S0HG@1236|Gammaproteobacteria,1XU1Q@135623|Vibrionales 135623|Vibrionales G COG1879 ABC-type sugar transport system, periplasmic component torT - - ko:K11930 - - - - ko00000 - - - Peripla_BP_1 k141_32895_3 1116375.VEJY3_19001 1.16e-105 305.0 COG1803@1|root,COG1803@2|Bacteria,1RD3D@1224|Proteobacteria,1S3XN@1236|Gammaproteobacteria,1XV9M@135623|Vibrionales 135623|Vibrionales G Methylglyoxal synthase mgsA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0008150,GO:0008152,GO:0008929,GO:0009058,GO:0009438,GO:0009987,GO:0016829,GO:0016835,GO:0016838,GO:0019242,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0071704,GO:1901576 4.2.3.3 ko:K01734 ko00640,ko01120,map00640,map01120 - R01016 RC00424 ko00000,ko00001,ko01000 - - - MGS k141_32895_4 1116375.VEJY3_18996 0.0 1313.0 COG0210@1|root,COG0210@2|Bacteria,1MVWI@1224|Proteobacteria,1RN1N@1236|Gammaproteobacteria,1XTAF@135623|Vibrionales 135623|Vibrionales L COG0210 Superfamily I DNA and RNA helicases helD - 3.6.4.12 ko:K03658 - - - - ko00000,ko01000,ko03400 - - - Helicase_IV_N,UvrD-helicase,UvrD_C k141_32895_5 1116375.VEJY3_18991 0.0 1312.0 COG1289@1|root,COG1289@2|Bacteria,1MWR1@1224|Proteobacteria,1RNIJ@1236|Gammaproteobacteria,1XTGG@135623|Vibrionales 135623|Vibrionales S membrane yccS - - - - - - - - - - - FUSC-like,FUSC_2 k141_32895_6 1116375.VEJY3_18986 1.65e-19 80.1 2AWVR@1|root,31NJU@2|Bacteria,1QKAH@1224|Proteobacteria,1TIE1@1236|Gammaproteobacteria,1XYYH@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_32895_7 223926.28808901 1.97e-49 157.0 2E3YH@1|root,32YVH@2|Bacteria,1NAJA@1224|Proteobacteria,1SD5Q@1236|Gammaproteobacteria,1XYDI@135623|Vibrionales 135623|Vibrionales S Bacterial inner membrane protein - - - - - - - - - - - - Imp-YgjV k141_32895_8 223926.28808896 8.37e-79 235.0 COG0789@1|root,COG0789@2|Bacteria,1RGX6@1224|Proteobacteria,1S8ZG@1236|Gammaproteobacteria,1XXF9@135623|Vibrionales 135623|Vibrionales K transcriptional regulators cueR - - ko:K19591 - M00769 - - ko00000,ko00002,ko01504,ko03000 - - - MerR,MerR-DNA-bind,MerR_1 k141_32895_9 1219076.N646_4093 1.78e-43 150.0 COG1609@1|root,COG1609@2|Bacteria,1MVUR@1224|Proteobacteria,1RN2K@1236|Gammaproteobacteria,1XTVU@135623|Vibrionales 135623|Vibrionales K Ribose operon repressor rbsR - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 k141_31522_1 1132442.KB889752_gene568 1.85e-106 320.0 COG1055@1|root,COG1055@2|Bacteria,1TPNN@1239|Firmicutes,4H9WV@91061|Bacilli,1ZBHC@1386|Bacillus 91061|Bacilli P Involved in arsenical resistance. Thought to form the channel of an arsenite pump ywrK - - ko:K03893 - - - - ko00000,ko02000 2.A.45.1,3.A.4.1 - - ArsB k141_1920_1 926569.ANT_28140 4.61e-94 286.0 COG0192@1|root,COG0192@2|Bacteria,2G5X0@200795|Chloroflexi 200795|Chloroflexi H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme metK GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 M00034,M00035,M00368,M00609 R00177,R04771 RC00021,RC01211 ko00000,ko00001,ko00002,ko01000 - - - S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N k141_23726_1 342610.Patl_3336 2.61e-23 101.0 COG0625@1|root,COG0625@2|Bacteria,1R3VG@1224|Proteobacteria,1S1GK@1236|Gammaproteobacteria 1236|Gammaproteobacteria O COG0625 Glutathione S-transferase - - - - - - - - - - - - GST_C,GST_N_3 k141_23726_2 1042377.AFPJ01000004_gene359 1.31e-06 47.4 2EBHR@1|root,335I6@2|Bacteria,1N8W4@1224|Proteobacteria,1SG3V@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_12922_1 985665.HPL003_05065 1.08e-14 73.6 COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,4HBVK@91061|Bacilli,26QF5@186822|Paenibacillaceae 91061|Bacilli L helicase deaD3 - 3.6.4.13 ko:K05592 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,Helicase_C k141_12922_2 218284.CCDN010000006_gene3541 5.82e-47 154.0 2AD85@1|root,312X5@2|Bacteria,1V735@1239|Firmicutes,4HIXA@91061|Bacilli,1ZGBJ@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_35468_1 1279017.AQYJ01000028_gene2321 5.62e-81 271.0 COG2982@1|root,COG2982@2|Bacteria,1MUME@1224|Proteobacteria,1RNPC@1236|Gammaproteobacteria,464KK@72275|Alteromonadaceae 1236|Gammaproteobacteria M Domain of Unknown Function (DUF748) - - - - - - - - - - - - DUF748,OmpA k141_35468_2 1279017.AQYJ01000023_gene3216 9.54e-181 520.0 COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,1RN5I@1236|Gammaproteobacteria,469UF@72275|Alteromonadaceae 1236|Gammaproteobacteria C Aconitase C-terminal domain - - 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_C k141_1921_1 1122915.AUGY01000012_gene3845 2.18e-63 205.0 COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,1TPE2@1239|Firmicutes,4H9WH@91061|Bacilli,26QN7@186822|Paenibacillaceae 91061|Bacilli P Rhodanese Homology Domain yrkH - - - - - - - - - - - Lactamase_B,Rhodanese k141_22389_1 1078085.HMPREF1210_00657 2.75e-56 198.0 COG1404@1|root,COG2755@1|root,COG1404@2|Bacteria,COG2755@2|Bacteria,1TPH1@1239|Firmicutes,4HBQH@91061|Bacilli 91061|Bacilli O Belongs to the peptidase S8 family prtS - 3.4.21.110,3.4.21.96 ko:K01361,ko:K08652 - - - - ko00000,ko01000,ko01002,ko03110 - - - FIVAR,Gram_pos_anchor,Inhibitor_I9,PA,Peptidase_S8,SLH,YSIRK_signal,fn3_5 k141_26017_1 396595.TK90_0540 0.000543 42.7 2EG5Q@1|root,339XK@2|Bacteria,1NGQ6@1224|Proteobacteria,1SHCX@1236|Gammaproteobacteria,1X1X4@135613|Chromatiales 135613|Chromatiales S Domain of unknown function (DUF4168) - - - - - - - - - - - - DUF4168 k141_19013_1 1042377.AFPJ01000030_gene442 9.54e-213 614.0 COG3240@1|root,COG3240@2|Bacteria,1RCCU@1224|Proteobacteria,1S2GX@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Phospholipase lecithinase hemolysin estA GO:0003674,GO:0003824,GO:0016289,GO:0016290,GO:0016787,GO:0016788,GO:0016790,GO:0047617,GO:0052689 - ko:K12686 - - - - ko00000,ko02000,ko02044 1.B.12.8 - - Autotransporter,Lipase_GDSL k141_3197_1 1294265.JCM21738_4909 2.57e-56 183.0 COG1196@1|root,COG1196@2|Bacteria,1TPW9@1239|Firmicutes,4HCS1@91061|Bacilli,1ZCPI@1386|Bacillus 91061|Bacilli D Putative exonuclease SbcCD, C subunit - - - - - - - - - - - - SbcCD_C k141_3197_2 1499685.CCFJ01000041_gene1126 4.22e-49 170.0 COG4924@1|root,COG4924@2|Bacteria,1TRVG@1239|Firmicutes,4HB8B@91061|Bacilli,1ZERZ@1386|Bacillus 91061|Bacilli S Protein of unknown function N-terminus (DUF3323) - - - - - - - - - - - - DUF2399,DUF3323 k141_1018_1 218284.CCDN010000001_gene1552 4.73e-116 352.0 COG0768@1|root,COG0768@2|Bacteria,1TQHY@1239|Firmicutes,4HAFX@91061|Bacilli,1ZBJM@1386|Bacillus 91061|Bacilli M penicillin-binding protein pbpH - - ko:K21465 ko00550,map00550 - - - ko00000,ko00001,ko01011 - - - PBP_dimer,Transpeptidase k141_6991_1 218284.CCDN010000007_gene3867 9.51e-186 523.0 COG4972@1|root,COG4972@2|Bacteria,1TSTJ@1239|Firmicutes,4HD01@91061|Bacilli,1ZCYF@1386|Bacillus 91061|Bacilli NU Pilus assembly protein - - - ko:K18640 - - - - ko00000,ko04812 - - - StbA k141_23727_2 1294265.JCM21738_2056 2.6e-211 585.0 COG1533@1|root,COG1533@2|Bacteria,1TPA3@1239|Firmicutes,4HACB@91061|Bacilli,1ZBPU@1386|Bacillus 91061|Bacilli L Spore photoproduct lyase splB GO:0003674,GO:0003824,GO:0003913,GO:0005488,GO:0005575,GO:0005623,GO:0016829,GO:0016830,GO:0042601,GO:0042763,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0070283,GO:0140097 4.1.99.14 ko:K03716 - - - - ko00000,ko01000 - - - - k141_30375_1 218284.CCDN010000001_gene1213 2.99e-70 229.0 COG0840@1|root,COG0840@2|Bacteria,1UV22@1239|Firmicutes,4IBKM@91061|Bacilli,1ZERB@1386|Bacillus 91061|Bacilli NT CHASE3 domain - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - CHASE3,MCPsignal k141_35470_1 1280953.HOC_01616 4.83e-81 256.0 COG4402@1|root,COG4402@2|Bacteria,1MVMM@1224|Proteobacteria,2U464@28211|Alphaproteobacteria,43WAC@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Uncharacterized protein conserved in bacteria (DUF2330) - - - - - - - - - - - - DUF2330 k141_4390_1 1453501.JELR01000002_gene55 4.02e-83 279.0 COG2911@1|root,COG2911@2|Bacteria,1MUVD@1224|Proteobacteria 1224|Proteobacteria M Protein conserved in bacteria tamB - - ko:K09800 - - - - ko00000,ko02000 - - - TamB k141_1019_2 441769.ABFU01000051_gene3802 1.38e-35 121.0 COG1349@1|root,COG1349@2|Bacteria,1VG5N@1239|Firmicutes,4HNPQ@91061|Bacilli,1ZHT3@1386|Bacillus 91061|Bacilli K COG1349 Transcriptional regulators of sugar metabolism ytzE - - - - - - - - - - - HTH_DeoR k141_6992_1 218284.CCDN010000001_gene1609 2.39e-84 251.0 COG1051@1|root,COG1051@2|Bacteria,1V9D6@1239|Firmicutes,4HICH@91061|Bacilli,1ZHU8@1386|Bacillus 91061|Bacilli F NUDIX hydrolase - - - - - - - - - - - - NUDIX k141_20960_1 1453501.JELR01000005_gene1619 4.05e-102 310.0 COG0497@1|root,COG0497@2|Bacteria,1PAB3@1224|Proteobacteria,1RZB5@1236|Gammaproteobacteria,468PN@72275|Alteromonadaceae 1236|Gammaproteobacteria L DNA recombination - - - - - - - - - - - - - k141_36372_1 358681.BBR47_28210 2.46e-51 172.0 COG4123@1|root,COG4123@2|Bacteria,1UJ5X@1239|Firmicutes,4IT37@91061|Bacilli,26V74@186822|Paenibacillaceae 91061|Bacilli S Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) - - - - - - - - - - - - Methyltransf_31,NAS k141_32898_1 1232410.KI421426_gene1474 1.42e-35 138.0 COG3264@1|root,COG3264@2|Bacteria,1QUDC@1224|Proteobacteria,43DHA@68525|delta/epsilon subdivisions,2X8P3@28221|Deltaproteobacteria 28221|Deltaproteobacteria M Mechanosensitive ion channel - - - - - - - - - - - - MS_channel k141_11748_1 1453501.JELR01000002_gene465 0.0 1150.0 COG1506@1|root,COG1506@2|Bacteria,1P6E1@1224|Proteobacteria,1RPRK@1236|Gammaproteobacteria,464ZW@72275|Alteromonadaceae 1236|Gammaproteobacteria E Dipeptidyl peptidase IV (DPP IV) N-terminal region dpp4 - 3.4.14.5 ko:K01278 ko04974,map04974 - - - ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 - - - DPPIV_N,Peptidase_S9 k141_10476_2 218284.CCDN010000005_gene3300 3.38e-114 332.0 COG0639@1|root,COG0639@2|Bacteria,1TPCI@1239|Firmicutes,4HBD8@91061|Bacilli,1ZBK8@1386|Bacillus 91061|Bacilli T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP prpE GO:0003674,GO:0003824,GO:0004721,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008138,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 3.1.3.16,3.6.1.41 ko:K01090,ko:K01525 ko00230,map00230 - R00125 RC00002 ko00000,ko00001,ko01000 - - - Metallophos k141_11790_2 218284.CCDN010000001_gene1743 3.66e-91 272.0 COG1284@1|root,COG1284@2|Bacteria,1V5G7@1239|Firmicutes,4HHDF@91061|Bacilli,1ZBEZ@1386|Bacillus 91061|Bacilli S Uncharacterised 5xTM membrane BCR, YitT family COG1284 yitE - - - - - - - - - - - YitT_membrane k141_11790_3 218284.CCDN010000001_gene1742 1.64e-58 187.0 COG0491@1|root,COG0491@2|Bacteria,1TR4H@1239|Firmicutes,4HBXR@91061|Bacilli,1ZDVA@1386|Bacillus 91061|Bacilli S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B k141_23762_1 1085623.GNIT_1612 1.16e-123 365.0 COG1902@1|root,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,1RR6H@1236|Gammaproteobacteria,4664Z@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family - - - - - - - - - - - - Oxidored_FMN k141_23762_2 35754.JNYJ01000025_gene8980 3.78e-07 53.9 COG0789@1|root,COG0789@2|Bacteria,2INKP@201174|Actinobacteria,4DEJD@85008|Micromonosporales 201174|Actinobacteria K MerR, DNA binding - - - ko:K08365 - - - - ko00000,ko03000 - - - MerR_1 k141_23762_3 1333856.L686_13295 4.1e-53 172.0 COG5579@1|root,COG5579@2|Bacteria,1RGXV@1224|Proteobacteria,1S6K5@1236|Gammaproteobacteria,1Z335@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria S Protein of unknown function (DUF1810) - - - - - - - - - - - - DUF1810 k141_23762_4 1123228.AUIH01000008_gene2432 8.84e-59 186.0 COG3565@1|root,COG3565@2|Bacteria,1RD7C@1224|Proteobacteria,1S6SD@1236|Gammaproteobacteria,1XJYN@135619|Oceanospirillales 135619|Oceanospirillales S dioxygenase of extradiol dioxygenase family - - - ko:K06991 - - - - ko00000 - - - Glyoxalase k141_29401_1 1042377.AFPJ01000004_gene412 1.11e-161 467.0 COG1668@1|root,COG1668@2|Bacteria,1R3RG@1224|Proteobacteria,1RQT1@1236|Gammaproteobacteria,46CSP@72275|Alteromonadaceae 1236|Gammaproteobacteria CP ABC-2 family transporter protein natB - - ko:K09696 ko02010,ko02020,map02010,map02020 M00253 - - ko00000,ko00001,ko00002,ko02000 3.A.1.115 - - ABC2_membrane_2,ABC2_membrane_3 k141_29401_2 1042377.AFPJ01000004_gene411 4.12e-121 352.0 COG4555@1|root,COG4555@2|Bacteria,1QU2T@1224|Proteobacteria,1RY2V@1236|Gammaproteobacteria,46CK1@72275|Alteromonadaceae 1236|Gammaproteobacteria CP ATPases associated with a variety of cellular activities natA - 3.6.3.7 ko:K09697 ko02010,ko02020,map02010,map02020 M00253 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.115 - - ABC_tran k141_29401_3 1279017.AQYJ01000011_gene3045 3.16e-193 553.0 COG0596@1|root,COG0596@2|Bacteria,1R6KU@1224|Proteobacteria,1RNTQ@1236|Gammaproteobacteria,467P9@72275|Alteromonadaceae 1236|Gammaproteobacteria S TAP-like protein - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_4 k141_29401_5 1042377.AFPJ01000004_gene408 1.29e-144 416.0 COG4989@1|root,COG4989@2|Bacteria,1MY3G@1224|Proteobacteria,1RRIC@1236|Gammaproteobacteria,4648X@72275|Alteromonadaceae 1236|Gammaproteobacteria S Oxidoreductase ydhF GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - - - - - - - - - - Aldo_ket_red k141_29401_6 1042377.AFPJ01000004_gene367 3.39e-72 224.0 COG1664@1|root,COG1664@2|Bacteria,1ND4H@1224|Proteobacteria,1SF92@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Polymer-forming cytoskeletal - - - - - - - - - - - - Bactofilin k141_29401_7 1453501.JELR01000005_gene1618 2.19e-102 316.0 2C1UX@1|root,33FGU@2|Bacteria,1NQE8@1224|Proteobacteria,1SJFD@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_35648_1 218284.CCDN010000001_gene713 1.16e-60 196.0 COG1161@1|root,COG1161@2|Bacteria,1TPM2@1239|Firmicutes,4HAAF@91061|Bacilli,1ZBES@1386|Bacillus 91061|Bacilli S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis yqeH GO:0003674,GO:0003824,GO:0003924,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019219,GO:0019222,GO:0022613,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0042254,GO:0044085,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0071840,GO:0080090,GO:0090329,GO:2000104,GO:2000112,GO:2000113 - ko:K06948 - - - - ko00000,ko03009 - - - MMR_HSR1 k141_35648_2 649639.Bcell_1568 1.88e-11 63.9 COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,4HD4R@91061|Bacilli,1ZANW@1386|Bacillus 91061|Bacilli E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) aroE GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000 - - - Shikimate_DH,Shikimate_dh_N k141_16485_1 1453501.JELR01000002_gene163 1.88e-81 259.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,464SM@72275|Alteromonadaceae 1236|Gammaproteobacteria JKL DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA rhlB GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0019904,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0090304,GO:0097718,GO:0140098,GO:1901360,GO:1901361,GO:1901575 3.6.4.13 ko:K03732 ko03018,map03018 M00394 - - ko00000,ko00001,ko00002,ko01000,ko03019 - - - DEAD,Helicase_C,RhlB k141_15172_2 1348657.M622_11875 1.08e-41 149.0 COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,2VKXU@28216|Betaproteobacteria,2KVSV@206389|Rhodocyclales 206389|Rhodocyclales V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD k141_21114_1 1453501.JELR01000002_gene850 1.17e-143 416.0 COG5434@1|root,COG5434@2|Bacteria,1MXP8@1224|Proteobacteria,1RRJZ@1236|Gammaproteobacteria,4644J@72275|Alteromonadaceae 1236|Gammaproteobacteria G Belongs to the glycosyl hydrolase 28 family - - - - - - - - - - - - Glyco_hydro_28,Pectate_lyase_3 k141_28176_2 1385512.N784_04100 4.8e-54 183.0 COG1366@1|root,COG1366@2|Bacteria,1UGQT@1239|Firmicutes,4HCRH@91061|Bacilli,2Y8NS@289201|Pontibacillus 91061|Bacilli T Positive regulator of sigma-B activity rsbR - - ko:K17763 - - - - ko00000,ko03021 - - - Rsbr_N,STAS k141_24941_1 218284.CCDN010000001_gene952 8.05e-74 224.0 COG0231@1|root,COG0231@2|Bacteria,1TR8P@1239|Firmicutes,4H9YX@91061|Bacilli,1ZAT9@1386|Bacillus 91061|Bacilli J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase efp GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02356 - - - - ko00000,ko03012 - - - EFP,EFP_N,Elong-fact-P_C k141_2136_1 1279017.AQYJ01000023_gene3243 1.33e-275 776.0 COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,464SF@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG2217 Cation transport ATPase ccoI - 3.6.3.4 ko:K01533 - - R00086 RC00002 ko00000,ko01000 3.A.3.5 - - ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase k141_20212_1 1453501.JELR01000002_gene645 6.27e-99 294.0 COG0697@1|root,COG0697@2|Bacteria,1MWMC@1224|Proteobacteria,1RQST@1236|Gammaproteobacteria,464KV@72275|Alteromonadaceae 1236|Gammaproteobacteria EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily yigM GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - EamA k141_31632_1 1123242.JH636435_gene1004 1.34e-05 53.1 COG4191@1|root,COG4191@2|Bacteria,2J07R@203682|Planctomycetes 203682|Planctomycetes T PAS fold - - - - - - - - - - - - HATPase_c,HisKA,PAS_3 k141_15193_2 1217714.F975_01138 3.53e-27 110.0 COG1309@1|root,COG1309@2|Bacteria,1ND64@1224|Proteobacteria,1RW6A@1236|Gammaproteobacteria,3NN3G@468|Moraxellaceae 1236|Gammaproteobacteria K YcdC-like protein, C-terminal region - - - - - - - - - - - - TetR_C_3,TetR_N k141_15193_3 421052.F945_02589 3.84e-54 186.0 COG1018@1|root,COG1018@2|Bacteria,1MU6E@1224|Proteobacteria,1RNA4@1236|Gammaproteobacteria,3NJUK@468|Moraxellaceae 1236|Gammaproteobacteria C 2Fe-2S iron-sulfur cluster binding domain - - - ko:K03863 ko00627,ko01120,map00627,map01120 - R05274 RC00392,RC01533 ko00000,ko00001 - - - FAD_binding_6,Fer2,NAD_binding_1 k141_15193_4 1157708.KB907473_gene1233 4.3e-92 290.0 COG0402@1|root,COG0402@2|Bacteria,1MX34@1224|Proteobacteria,2VJKS@28216|Betaproteobacteria,4ABDF@80864|Comamonadaceae 28216|Betaproteobacteria F PFAM amidohydrolase - - 3.5.4.1 ko:K01485 ko00240,ko00330,ko01100,map00240,map00330,map01100 - R00974,R01411,R02922 RC00074,RC00514,RC00809 ko00000,ko00001,ko01000 - - - Amidohydro_3 k141_15193_5 1336245.JAGO01000015_gene2052 4.18e-58 183.0 COG0251@1|root,COG0251@2|Bacteria,1RG2H@1224|Proteobacteria,1RSJD@1236|Gammaproteobacteria 1236|Gammaproteobacteria J translation initiation inhibitor, yjgF family - - 3.5.99.10 ko:K09022 - - R11098,R11099 RC03275,RC03354 ko00000,ko01000 - - - Ribonuc_L-PSP k141_24944_1 1294265.JCM21738_997 4.45e-75 231.0 COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HANF@91061|Bacilli,1ZS27@1386|Bacillus 91061|Bacilli T Histidine kinase - - - - - - - - - - - - HAMP,HATPase_c,HisKA k141_16495_1 218284.CCDN010000001_gene797 2.62e-134 386.0 COG1208@1|root,COG1208@2|Bacteria,1VDBC@1239|Firmicutes,4IS8X@91061|Bacilli,1ZDK6@1386|Bacillus 91061|Bacilli GJM Nucleotidyl transferase - - 2.7.7.13,5.4.2.8 ko:K00966,ko:K16881 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 M00114,M00361,M00362 R00885,R01818 RC00002,RC00408 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transferase,PGM_PMM_I k141_21157_1 333138.LQ50_18370 1.49e-36 133.0 2B68X@1|root,31Z68@2|Bacteria,1V93N@1239|Firmicutes,4HIJ8@91061|Bacilli,1ZFXK@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_21157_2 1121090.KB894691_gene2616 1.91e-31 119.0 COG1131@1|root,COG1131@2|Bacteria,1TQD5@1239|Firmicutes,4HBW8@91061|Bacilli,1ZCFU@1386|Bacillus 91061|Bacilli V ABC transporter - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_34346_1 1294265.JCM21738_4754 9.61e-98 285.0 COG1624@1|root,COG1624@2|Bacteria,1TPRW@1239|Firmicutes,4H9XZ@91061|Bacilli,1ZBIU@1386|Bacillus 91061|Bacilli S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria dacA GO:0003674,GO:0003824,GO:0004016,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0009975,GO:0016020,GO:0016021,GO:0016829,GO:0016849,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 2.7.7.85 ko:K18672 - - - - ko00000,ko01000 - - - DisA_N k141_34346_2 1294265.JCM21738_4755 3.69e-45 149.0 COG4856@1|root,COG4856@2|Bacteria,1TSIV@1239|Firmicutes,4HD8Y@91061|Bacilli,1ZB2T@1386|Bacillus 91061|Bacilli S protein conserved in bacteria ybbR GO:0008150,GO:0031279,GO:0031281,GO:0043085,GO:0044093,GO:0045761,GO:0045762,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009 - - - - - - - - - - YbbR k141_28201_1 1116375.VEJY3_10200 2.84e-224 631.0 COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,1RNGV@1236|Gammaproteobacteria,1XT19@135623|Vibrionales 135623|Vibrionales L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision uvrC GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009380,GO:0009381,GO:0009987,GO:0016787,GO:0016788,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - ko:K03703 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - GIY-YIG,HHH,HHH_5,UVR,UvrC_HhH_N k141_28201_2 1116375.VEJY3_10205 6.16e-150 422.0 COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,1RQ1J@1236|Gammaproteobacteria,1XUFX@135623|Vibrionales 135623|Vibrionales K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain sirA - - ko:K07689 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 M00475 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg k141_28201_3 1116375.VEJY3_10210 0.0 1462.0 COG0417@1|root,COG0417@2|Bacteria,1MVY9@1224|Proteobacteria,1RMQ1@1236|Gammaproteobacteria,1XTIT@135623|Vibrionales 135623|Vibrionales L COG0417 DNA polymerase elongation subunit (family B) polB - 2.7.7.7 ko:K02336 - - - - ko00000,ko01000,ko03400 - - - DNA_pol_B,DNA_pol_B_exo1 k141_28201_4 674977.VMC_25510 1.83e-160 452.0 COG1708@1|root,COG1708@2|Bacteria,1RID1@1224|Proteobacteria,1S9KW@1236|Gammaproteobacteria,1XTT0@135623|Vibrionales 135623|Vibrionales S nucleotidyltransferase activity - - - - - - - - - - - - NTP_transf_2 k141_28201_5 223926.28806940 1.73e-125 358.0 COG0231@1|root,COG0231@2|Bacteria,1MW2J@1224|Proteobacteria,1SZPH@1236|Gammaproteobacteria,1Y2WN@135623|Vibrionales 135623|Vibrionales J COG0231 Translation elongation factor P (EF-P) translation initiation factor 5A (eIF-5A) yeiP - - ko:K02356 - - - - ko00000,ko03012 - - - EFP,EFP_N,Elong-fact-P_C k141_28201_6 223926.28806941 2.34e-70 212.0 COG3099@1|root,COG3099@2|Bacteria,1RE1F@1224|Proteobacteria,1S43E@1236|Gammaproteobacteria,1XY16@135623|Vibrionales 135623|Vibrionales S Belongs to the UPF0263 family - - - ko:K09901 - - - - ko00000 - - - DUF440 k141_28201_7 1219076.N646_1033 4.22e-215 595.0 COG1187@1|root,COG1187@2|Bacteria,1MUCE@1224|Proteobacteria,1RQU0@1236|Gammaproteobacteria,1XUG0@135623|Vibrionales 135623|Vibrionales J Belongs to the pseudouridine synthase RsuA family rluB GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.22 ko:K06178 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 k141_28201_8 1116375.VEJY3_10235 1.29e-10 63.5 COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,1SI25@1236|Gammaproteobacteria,1XVQT@135623|Vibrionales 135623|Vibrionales Q Haemolysin-type calcium-binding repeat (2 copies) - - - - - - - - - - - - HemolysinCabind k141_37775_1 1453501.JELR01000001_gene3231 3.46e-128 373.0 COG5434@1|root,COG5434@2|Bacteria,1MUGF@1224|Proteobacteria,1RS20@1236|Gammaproteobacteria,46AM6@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the glycosyl hydrolase 28 family - - - - - - - - - - - - Beta_helix k141_4570_1 561229.Dd1591_1048 1.11e-203 574.0 COG1455@1|root,COG1455@2|Bacteria,1MXAG@1224|Proteobacteria,1RQGX@1236|Gammaproteobacteria,2JF9Q@204037|Dickeya 1236|Gammaproteobacteria G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane celB - - ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 - - PTS_EIIC k141_4570_2 1224318.DT73_10560 2.79e-185 519.0 COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,1RS6U@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_4570_3 1224318.DT73_10555 8.09e-80 239.0 COG5517@1|root,COG5517@2|Bacteria,1REK5@1224|Proteobacteria,1SC51@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q SnoaL-like domain - - - - - - - - - - - - SnoaL_4 k141_4570_4 1224318.DT73_10550 7.6e-196 547.0 COG2141@1|root,COG2141@2|Bacteria,1MWDV@1224|Proteobacteria,1RYCM@1236|Gammaproteobacteria 1236|Gammaproteobacteria C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - - - - - - - - - - Bac_luciferase k141_4570_5 1116375.VEJY3_18361 3.5e-88 264.0 COG0110@1|root,COG0110@2|Bacteria,1RA4J@1224|Proteobacteria,1S26W@1236|Gammaproteobacteria 1236|Gammaproteobacteria S COG0110 Acetyltransferase (isoleucine patch superfamily) - - - - - - - - - - - - Hexapep,Hexapep_2,Mac k141_29638_1 218284.CCDN010000001_gene1513 2.6e-194 561.0 COG1112@1|root,COG1112@2|Bacteria,1UNF1@1239|Firmicutes,4IPKF@91061|Bacilli,1ZDR8@1386|Bacillus 91061|Bacilli L COG1112 Superfamily I DNA and RNA helicases and helicase subunits - - - - - - - - - - - - AAA_11,AAA_12 k141_8002_1 1121438.JNJA01000006_gene249 1.95e-18 87.0 COG0726@1|root,COG1215@1|root,COG3858@1|root,COG0726@2|Bacteria,COG1215@2|Bacteria,COG3858@2|Bacteria,1MXG7@1224|Proteobacteria,42Q7W@68525|delta/epsilon subdivisions,2WPUI@28221|Deltaproteobacteria,2MAQQ@213115|Desulfovibrionales 28221|Deltaproteobacteria M Glycosyl hydrolases family 18 - - - - - - - - - - - - Glyco_hydro_18,Glyco_tranf_2_3,Polysacc_deac_1 k141_17647_1 665959.HMPREF1013_00719 3.1e-185 525.0 COG1306@1|root,COG1306@2|Bacteria,1TQZV@1239|Firmicutes,4HAPK@91061|Bacilli,1ZCIN@1386|Bacillus 91061|Bacilli S Putative glycosyl hydrolase domain - - - - - - - - - - - - DUF4015 k141_36469_1 1294265.JCM21738_2317 3.97e-104 300.0 COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,4HHA1@91061|Bacilli,1ZFRG@1386|Bacillus 91061|Bacilli O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides ppiB - 5.2.1.8 ko:K03768 - - - - ko00000,ko01000,ko03110 - - - Pro_isomerase k141_36469_2 1294265.JCM21738_2318 1.2e-140 400.0 2D1P6@1|root,32TB3@2|Bacteria,1VAU9@1239|Firmicutes,4HKUB@91061|Bacilli,1ZEUG@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - Sigma70_r4_2 k141_15194_1 1453501.JELR01000006_gene13 6.56e-56 196.0 COG4223@1|root,COG4223@2|Bacteria,1N10X@1224|Proteobacteria,1RYCQ@1236|Gammaproteobacteria,46D2D@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF1631) - - - - - - - - - - - - DUF1631 k141_21158_1 935836.JAEL01000042_gene4933 1.17e-79 240.0 COG1670@1|root,COG1670@2|Bacteria,1V576@1239|Firmicutes,4HH3E@91061|Bacilli,1ZRE3@1386|Bacillus 91061|Bacilli J Acetyltransferase (GNAT) domain - - 2.3.1.128 ko:K03790 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 k141_3368_2 42565.FP66_08285 4.5e-74 229.0 COG1344@1|root,COG1344@2|Bacteria,1MV1N@1224|Proteobacteria,1RN0Y@1236|Gammaproteobacteria 1236|Gammaproteobacteria N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella - - - - - - - - - - - - Flagellin_C,Flagellin_N k141_8003_1 1123237.Salmuc_02991 2.69e-106 326.0 COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,2TQNY@28211|Alphaproteobacteria 28211|Alphaproteobacteria KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance spoT - 2.7.6.5,3.1.7.2 ko:K00951,ko:K01139 ko00230,map00230 - R00336,R00429 RC00002,RC00078 ko00000,ko00001,ko01000,ko03009 - - - ACT_4,HD_4,RelA_SpoT,TGS k141_29639_1 1042377.AFPJ01000024_gene771 2.94e-148 420.0 COG0463@1|root,COG0463@2|Bacteria,1QX0V@1224|Proteobacteria,1T32V@1236|Gammaproteobacteria,4647P@72275|Alteromonadaceae 1236|Gammaproteobacteria M Glycosyltransferase like family 2 - - - - - - - - - - - - Glyco_transf_7C,Glycos_transf_2 k141_2141_2 218284.CCDN010000006_gene3531 1.31e-72 228.0 COG0673@1|root,COG0673@2|Bacteria,1TR8S@1239|Firmicutes,4HBHI@91061|Bacilli,1ZDU7@1386|Bacillus 91061|Bacilli S Oxidoreductase yvaA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0070401,GO:0070402,GO:0097159,GO:0102497,GO:1901265,GO:1901363 1.1.1.371 ko:K16044 ko00562,ko01120,map00562,map01120 - R09954 RC00182 ko00000,ko00001,ko01000 - - - GFO_IDH_MocA,GFO_IDH_MocA_C k141_17648_1 1123279.ATUS01000001_gene2469 8.77e-19 84.7 2CJ6B@1|root,32S9B@2|Bacteria,1N2I4@1224|Proteobacteria,1S8Z8@1236|Gammaproteobacteria,1J6QJ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Thermostable hemolysin - - - - - - - - - - - - T_hemolysin k141_17648_2 1485544.JQKP01000011_gene736 5.69e-20 92.4 COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,2VI0U@28216|Betaproteobacteria,44V2C@713636|Nitrosomonadales 28216|Betaproteobacteria I AMP-binding enzyme - - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding k141_16497_1 1294265.JCM21738_4387 5.56e-63 196.0 COG1670@1|root,COG1670@2|Bacteria,1V3NE@1239|Firmicutes,4HG1N@91061|Bacilli,1ZEC8@1386|Bacillus 91061|Bacilli J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins - - - ko:K03817 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 k141_30498_2 1116375.VEJY3_01780 0.0 869.0 COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,1RN13@1236|Gammaproteobacteria,1XVWG@135623|Vibrionales 135623|Vibrionales F COG0402 Cytosine deaminase and related metal-dependent hydrolases - - 3.5.4.32 ko:K18456 - - - - ko00000,ko01000 - - - Amidohydro_1 k141_30498_3 1116375.VEJY3_01775 0.0 1027.0 COG0204@1|root,COG3176@1|root,COG0204@2|Bacteria,COG3176@2|Bacteria,1MWIM@1224|Proteobacteria,1RQD4@1236|Gammaproteobacteria,1XTB5@135623|Vibrionales 135623|Vibrionales I Hemolysin - - - - - - - - - - - - Acetyltransf_5,Acyltransferase k141_30498_4 223926.28805353 0.0 1176.0 COG2213@1|root,COG4668@1|root,COG2213@2|Bacteria,COG4668@2|Bacteria,1MUPU@1224|Proteobacteria,1RNAG@1236|Gammaproteobacteria,1XSK5@135623|Vibrionales 135623|Vibrionales G PTS system mannitol-specific transporter subunit IICBA mtlA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0015166,GO:0015318,GO:0015575,GO:0015791,GO:0015797,GO:0015850,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563,GO:1901618 2.7.1.197 ko:K02798,ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 M00274 R02704 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1.12,4.A.2.1.2,4.A.2.1.24,4.A.2.1.5 - - PTS_EIIA_2,PTS_EIIC,PTS_IIB k141_30498_5 1116375.VEJY3_01765 1.4e-262 721.0 COG0246@1|root,COG0246@2|Bacteria,1MXV8@1224|Proteobacteria,1RPCP@1236|Gammaproteobacteria,1XTTE@135623|Vibrionales 135623|Vibrionales C hexitol metabolic process mtlD GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006059,GO:0006066,GO:0008150,GO:0008152,GO:0008926,GO:0009056,GO:0009987,GO:0016052,GO:0016491,GO:0016614,GO:0016616,GO:0019400,GO:0019405,GO:0019407,GO:0019592,GO:0019594,GO:0019751,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046164,GO:0046174,GO:0055114,GO:0071704,GO:1901575,GO:1901615,GO:1901616 1.1.1.17 ko:K00009 ko00051,map00051 - R02703 RC00085 ko00000,ko00001,ko01000 - - - Mannitol_dh,Mannitol_dh_C k141_30498_6 1116375.VEJY3_01760 4.15e-118 338.0 COG3722@1|root,COG3722@2|Bacteria,1NEDY@1224|Proteobacteria,1RPCM@1236|Gammaproteobacteria,1XVK5@135623|Vibrionales 135623|Vibrionales K Mannitol operon repressor mtlR - - ko:K02562 - - - - ko00000,ko03000 - - - MtlR k141_31633_1 223926.28809356 1.72e-172 504.0 COG1251@1|root,COG1251@2|Bacteria,1MW58@1224|Proteobacteria,1RNGY@1236|Gammaproteobacteria,1XUM5@135623|Vibrionales 135623|Vibrionales C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family - - 1.7.1.15 ko:K00362 ko00910,ko01120,map00910,map01120 M00530 R00787 RC00176 ko00000,ko00001,ko00002,ko01000 - - - Fer2_BFD,NIR_SIR,NIR_SIR_ferr,Pyr_redox_2 k141_15195_1 1121085.AUCI01000017_gene2518 1.19e-13 70.9 29H5Q@1|root,30439@2|Bacteria,1V63Q@1239|Firmicutes,4HHR2@91061|Bacilli,1ZE9T@1386|Bacillus 91061|Bacilli S Nuclease-related domain - - - - - - - - - - - - NERD k141_17649_1 218284.CCDN010000008_gene4175 6.29e-91 275.0 COG2141@1|root,COG2141@2|Bacteria,1TPRS@1239|Firmicutes,4H9R2@91061|Bacilli,1ZB1E@1386|Bacillus 91061|Bacilli C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases ywcH GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - - - - - - - - - - Bac_luciferase k141_36471_1 1042377.AFPJ01000052_gene1551 9.45e-79 249.0 COG3307@1|root,COG3307@2|Bacteria,1N225@1224|Proteobacteria,1RQWW@1236|Gammaproteobacteria,465GX@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG3307 Lipid A core - O-antigen ligase and related enzymes - - - - - - - - - - - - Wzy_C k141_29641_1 1294265.JCM21738_2145 2.83e-64 203.0 2BZRV@1|root,2Z8AV@2|Bacteria,1UX40@1239|Firmicutes,4HAVP@91061|Bacilli,1ZDM4@1386|Bacillus 91061|Bacilli S Nuclease-related domain - - - - - - - - - - - - NERD k141_34348_1 1122194.AUHU01000006_gene612 1.59e-152 452.0 COG3256@1|root,COG3256@2|Bacteria,1MVT1@1224|Proteobacteria,1RQ01@1236|Gammaproteobacteria,464BD@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG3256 Nitric oxide reductase large subunit norB - 1.7.2.5 ko:K04561 ko00910,ko01120,map00910,map01120 M00529 R00294 RC02794 ko00000,ko00001,ko00002,ko01000 3.D.4.10 - - COX1 k141_4573_2 1116375.VEJY3_17221 9.27e-65 206.0 COG3608@1|root,COG3608@2|Bacteria,1MUAA@1224|Proteobacteria,1RNQQ@1236|Gammaproteobacteria,1XSB8@135623|Vibrionales 135623|Vibrionales S Succinylglutamate desuccinylase / Aspartoacylase family - - 3.5.1.125 ko:K15784 ko00260,ko01100,map00260,map01100 - R09801 RC00064,RC00300 ko00000,ko00001,ko01000 - - - AstE_AspA k141_8004_2 406124.ACPC01000047_gene1810 1.78e-100 299.0 COG4326@1|root,COG4326@2|Bacteria,1TPEA@1239|Firmicutes,4HBPW@91061|Bacilli,1ZBFU@1386|Bacillus 91061|Bacilli S COG4326 Sporulation control protein spo0M - - ko:K06377 - - - - ko00000 - - - Spo0M k141_17650_1 338963.Pcar_1752 1.78e-24 102.0 COG4962@1|root,COG4962@2|Bacteria,1R7EN@1224|Proteobacteria,42NAK@68525|delta/epsilon subdivisions,2WIYX@28221|Deltaproteobacteria,43SA4@69541|Desulfuromonadales 28221|Deltaproteobacteria U PFAM type II secretion system protein E - - - ko:K02283,ko:K03609 - - - - ko00000,ko02035,ko02044,ko03036,ko04812 - - - CbiA,FHA,T2SSE k141_16498_1 218284.CCDN010000002_gene2130 8.56e-84 260.0 COG4191@1|root,COG4191@2|Bacteria,1VCNJ@1239|Firmicutes,4HVBX@91061|Bacilli,1ZS41@1386|Bacillus 91061|Bacilli T Histidine kinase - - 2.7.13.3 ko:K02491,ko:K13533 ko02020,map02020 M00485 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - 5TM-5TMR_LYT,HATPase_c,HisKA,LytTR,MASE3,PAS,PAS_3,PAS_4,PAS_9 k141_28204_1 218284.CCDN010000001_gene69 1.31e-71 221.0 COG2302@1|root,COG2302@2|Bacteria,1U5V2@1239|Firmicutes,4HD3F@91061|Bacilli,1ZC97@1386|Bacillus 91061|Bacilli S conserved protein, contains S4-like domain ylmH - - - - - - - - - - - S4 k141_3370_1 1123053.AUDG01000014_gene2098 1.7e-09 61.2 COG3751@1|root,COG3751@2|Bacteria,1RBXB@1224|Proteobacteria,1RR8W@1236|Gammaproteobacteria,1WWUG@135613|Chromatiales 135613|Chromatiales O 2OG-Fe(II) oxygenase superfamily - - - - - - - - - - - - 2OG-FeII_Oxy_3 k141_15228_1 1453501.JELR01000002_gene180 1.62e-73 228.0 COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,1RP23@1236|Gammaproteobacteria,464HJ@72275|Alteromonadaceae 1236|Gammaproteobacteria I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol ispE GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006629,GO:0006720,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050515,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576 2.7.1.148 ko:K00919 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05634 RC00002,RC01439 ko00000,ko00001,ko00002,ko01000 - - iEC55989_1330.EC55989_1304 GHMP_kinases_C,GHMP_kinases_N k141_4605_1 218284.CCDN010000002_gene2144 7.43e-147 425.0 COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,4H9W6@91061|Bacilli,1ZD0J@1386|Bacillus 91061|Bacilli G Belongs to the FGGY kinase family gntK - 2.7.1.12 ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 - R01737 RC00002,RC00017 ko00000,ko00001,ko01000 - - - FGGY_C,FGGY_N k141_34382_1 218284.CCDN010000001_gene1160 7.93e-95 279.0 COG4474@1|root,COG4474@2|Bacteria,1V6SM@1239|Firmicutes,4HJGM@91061|Bacilli,1ZFYS@1386|Bacillus 91061|Bacilli S Belongs to the UPF0398 family ypsA - - - - - - - - - - - DUF1273 k141_2182_1 1453501.JELR01000005_gene1653 5.08e-77 250.0 COG4206@1|root,COG4206@2|Bacteria,1QUGQ@1224|Proteobacteria,1T241@1236|Gammaproteobacteria,464Q2@72275|Alteromonadaceae 1236|Gammaproteobacteria H TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_33126_1 1453501.JELR01000002_gene1359 7.92e-102 316.0 COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,1RPFM@1236|Gammaproteobacteria,4673P@72275|Alteromonadaceae 1236|Gammaproteobacteria M protein involved in outer membrane biogenesis asmA - - ko:K07289 - - - - ko00000 - - - AsmA k141_15229_1 218284.CCDN010000008_gene4085 1.1e-43 152.0 COG4585@1|root,COG4585@2|Bacteria,1TQI3@1239|Firmicutes,4HAUU@91061|Bacilli,1ZDAA@1386|Bacillus 91061|Bacilli T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase degS - 2.7.13.3 ko:K07777 ko02020,map02020 M00478 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - DegS,HATPase_c,HisKA_3 k141_3403_1 1502770.JQMG01000001_gene2005 8.38e-43 155.0 COG5316@1|root,COG5316@2|Bacteria,1QCVP@1224|Proteobacteria,2VNEJ@28216|Betaproteobacteria,2KKQV@206350|Nitrosomonadales 206350|Nitrosomonadales S Domain of unknown function (DUF4139) - - - - - - - - - - - - DUF4139 k141_8040_1 218284.CCDN010000001_gene767 7.24e-71 221.0 COG0761@1|root,COG0761@2|Bacteria,1UHT7@1239|Firmicutes,4H9S4@91061|Bacilli,1ZAUG@1386|Bacillus 91061|Bacilli IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis ispH - 1.17.7.4 ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05884,R08210 RC01137,RC01487 ko00000,ko00001,ko00002,ko01000 - - - LYTB k141_8040_2 218284.CCDN010000001_gene766 3.5e-34 126.0 COG0327@1|root,COG0327@2|Bacteria,1TQ27@1239|Firmicutes,4H9NY@91061|Bacilli,1ZAPV@1386|Bacillus 91061|Bacilli S Belongs to the GTP cyclohydrolase I type 2 NIF3 family yqfO GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - - - - - - - - - - NIF3 k141_37814_2 1243664.CAVL020000054_gene3053 7.89e-93 283.0 COG0719@1|root,COG0719@2|Bacteria,1TQ21@1239|Firmicutes,4HA1Z@91061|Bacilli,1ZCDS@1386|Bacillus 91061|Bacilli O FeS cluster assembly sufB - - ko:K07033,ko:K09014 - - - - ko00000 - - - UPF0051 k141_4606_1 1294265.JCM21738_3190 3.79e-154 438.0 COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4H9TK@91061|Bacilli,1ZBTF@1386|Bacillus 91061|Bacilli S COG0488 ATPase components of ABC transporters with duplicated ATPase domains yfmR - - ko:K15738 - - - - ko00000,ko02000 3.A.1.120.6 - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn k141_4606_2 1294265.JCM21738_3191 1.43e-31 115.0 COG1418@1|root,COG1418@2|Bacteria,1V7IZ@1239|Firmicutes,4HIVB@91061|Bacilli,1ZB0E@1386|Bacillus 91061|Bacilli S phosphohydrolase ypgQ - - ko:K06950 - - - - ko00000 - - - HD k141_33127_1 1279017.AQYJ01000022_gene2616 8.33e-43 152.0 2EDVS@1|root,337QX@2|Bacteria,1NEZW@1224|Proteobacteria,1SCKV@1236|Gammaproteobacteria,46C7E@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_36509_1 493475.GARC_0244 1.14e-89 298.0 COG1629@1|root,COG4771@2|Bacteria,1MW4X@1224|Proteobacteria,1RPVY@1236|Gammaproteobacteria,465N5@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - CarboxypepD_reg,Plug,TonB_dep_Rec k141_10621_1 1219077.VAZ01S_070_00230 9.46e-39 133.0 COG0118@1|root,COG0118@2|Bacteria,1MU4X@1224|Proteobacteria,1RRP3@1236|Gammaproteobacteria,1XUI3@135623|Vibrionales 135623|Vibrionales E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR hisH GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - - GATase k141_10621_2 29495.EA26_15775 2.12e-170 476.0 COG0106@1|root,COG0106@2|Bacteria,1MW6S@1224|Proteobacteria,1RN3M@1236|Gammaproteobacteria,1XUYR@135623|Vibrionales 135623|Vibrionales E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase hisA GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04640 RC00945 ko00000,ko00001,ko00002,ko01000 - - - His_biosynth k141_10621_3 870967.VIS19158_15384 1.38e-87 262.0 COG0107@1|root,COG0107@2|Bacteria,1MUS0@1224|Proteobacteria,1RPJQ@1236|Gammaproteobacteria,1XT21@135623|Vibrionales 135623|Vibrionales E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit hisF GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - - His_biosynth k141_16537_1 42565.FP66_05115 5.38e-20 91.3 COG3852@1|root,COG3852@2|Bacteria,1MVN6@1224|Proteobacteria,1RN15@1236|Gammaproteobacteria,1XHHE@135619|Oceanospirillales 135619|Oceanospirillales T Histidine kinase ntrB - 2.7.13.3 ko:K07708 ko02020,map02020 M00497 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS,PAS_4,PAS_8 k141_28520_1 1453501.JELR01000001_gene2929 2.6e-115 359.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,466AN@72275|Alteromonadaceae 1236|Gammaproteobacteria V AcrB/AcrD/AcrF family bepG - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran k141_36759_1 1042377.AFPJ01000043_gene849 1.75e-80 256.0 COG0500@1|root,COG1073@1|root,COG1073@2|Bacteria,COG2226@2|Bacteria,1PA5F@1224|Proteobacteria,1RY7A@1236|Gammaproteobacteria,465B1@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway bioC GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008757,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0010340,GO:0016053,GO:0016740,GO:0016741,GO:0016787,GO:0016788,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032259,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0052689,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.197 ko:K02169 ko00780,ko01100,map00780,map01100 M00572 R09543 RC00003,RC00460 ko00000,ko00001,ko00002,ko01000 - - iECP_1309.ECP_0791,iSBO_1134.SBO_0664,iSFV_1184.SFV_0760,iSF_1195.SF0727,iSFxv_1172.SFxv_0792,iSSON_1240.SSON_0756,iS_1188.S0768,iSbBS512_1146.SbBS512_E2575 Methyltransf_11 k141_36760_1 1294265.JCM21738_3641 3.81e-87 272.0 COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,4HACG@91061|Bacilli,1ZBBF@1386|Bacillus 91061|Bacilli S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid yabM GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03328 - - - - ko00000 2.A.66.2 - - Polysacc_synt,Polysacc_synt_C k141_28522_1 218284.CCDN010000006_gene3629 6.02e-49 164.0 COG0391@1|root,COG0391@2|Bacteria,1TPNV@1239|Firmicutes,4HA0Z@91061|Bacilli,1ZB2R@1386|Bacillus 91061|Bacilli S Required for morphogenesis under gluconeogenic growth conditions yvcK - - - - - - - - - - - UPF0052 k141_28522_2 218284.CCDN010000006_gene3628 4.13e-64 203.0 COG1481@1|root,COG1481@2|Bacteria,1TP2X@1239|Firmicutes,4HB4H@91061|Bacilli,1ZBKY@1386|Bacillus 91061|Bacilli K May be required for sporulation whiA GO:0008150,GO:0043937,GO:0050789,GO:0050793,GO:0065007 - ko:K09762 - - - - ko00000 - - - HTH_WhiA,LAGLIDADG_WhiA,WhiA_N k141_8296_3 1173027.Mic7113_0851 5.67e-69 227.0 COG1866@1|root,COG1866@2|Bacteria,1G1KI@1117|Cyanobacteria,1H944@1150|Oscillatoriales 1117|Cyanobacteria H Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA pckA - 4.1.1.49 ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 M00003,M00170 R00341 RC00002,RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPCK_ATP k141_30776_1 935836.JAEL01000007_gene2900 2.14e-154 455.0 COG2225@1|root,COG2225@2|Bacteria,1UA0Z@1239|Firmicutes,4HBPG@91061|Bacilli 91061|Bacilli C Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA glcB - 2.3.3.9 ko:K01638 ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200 M00012 R00472 RC00004,RC00308,RC02747 ko00000,ko00001,ko00002,ko01000 - - - Malate_synthase k141_28525_1 945550.VISI1226_09574 2.37e-99 297.0 COG0765@1|root,COG0765@2|Bacteria,1MX3E@1224|Proteobacteria,1SPYP@1236|Gammaproteobacteria,1Y2TY@135623|Vibrionales 135623|Vibrionales P COG0765 ABC-type amino acid transport system, permease component - - - ko:K02029 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 k141_30777_1 218284.CCDN010000001_gene1932 1.14e-120 359.0 COG1766@1|root,COG1766@2|Bacteria,1TRK0@1239|Firmicutes,4HBF0@91061|Bacilli,1ZAZN@1386|Bacillus 91061|Bacilli N The M ring may be actively involved in energy transduction fliF - - ko:K02409 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 - - YscJ_FliF,YscJ_FliF_C k141_15412_1 1078085.HMPREF1210_02092 3.99e-105 342.0 COG1404@1|root,COG1404@2|Bacteria,1TPH1@1239|Firmicutes,4HBQH@91061|Bacilli 91061|Bacilli O Belongs to the peptidase S8 family prtS - 3.4.21.110,3.4.21.96 ko:K01361,ko:K08652 - - - - ko00000,ko01000,ko01002,ko03110 - - - FIVAR,Gram_pos_anchor,Inhibitor_I9,PA,Peptidase_S8,SLH,YSIRK_signal,fn3_5 k141_30779_1 1294265.JCM21738_4414 1.1e-38 137.0 COG0006@1|root,COG0006@2|Bacteria,1TQ6R@1239|Firmicutes,4HA5I@91061|Bacilli,1ZBZE@1386|Bacillus 91061|Bacilli E COG0006 Xaa-Pro aminopeptidase pepQ - 3.4.13.9 ko:K01271 - - - - ko00000,ko01000,ko01002 - - - Creatinase_N,Peptidase_M24 k141_15413_2 1453501.JELR01000002_gene687 1.36e-36 138.0 COG3605@1|root,COG3605@2|Bacteria,1QTTV@1224|Proteobacteria,1T1H2@1236|Gammaproteobacteria,464IT@72275|Alteromonadaceae 1236|Gammaproteobacteria T Belongs to the PEP-utilizing enzyme family ptsP GO:0003674,GO:0003824,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008965,GO:0009987,GO:0010033,GO:0010243,GO:0016310,GO:0016740,GO:0016772,GO:0016775,GO:0019538,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050896,GO:0071704,GO:1901564,GO:1901698 2.7.3.9 ko:K08484 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 - - - GAF,GAF_2,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C k141_8301_1 1116375.VEJY3_11365 2.75e-74 244.0 COG1025@1|root,COG1025@2|Bacteria,1QTVC@1224|Proteobacteria,1T1IG@1236|Gammaproteobacteria,1XT1Q@135623|Vibrionales 135623|Vibrionales O Belongs to the peptidase M16 family ptrA - - - - - - - - - - - Peptidase_M16,Peptidase_M16_C,Peptidase_M16_M k141_8301_2 1116375.VEJY3_11360 1.91e-101 294.0 COG2062@1|root,COG2062@2|Bacteria,1NAAE@1224|Proteobacteria,1SAT1@1236|Gammaproteobacteria,1XXBT@135623|Vibrionales 135623|Vibrionales T Phosphohistidine phosphatase sixA sixA - - ko:K08296 - - - - ko00000,ko01000 - - - His_Phos_1 k141_8301_3 29495.EA26_16845 1.02e-35 124.0 COG2840@1|root,COG2840@2|Bacteria,1MVS6@1224|Proteobacteria,1RPXD@1236|Gammaproteobacteria,1XUS2@135623|Vibrionales 135623|Vibrionales S Belongs to the UPF0115 family yfcN - - - - - - - - - - - Smr k141_28531_1 1453501.JELR01000002_gene1141 2.62e-31 119.0 COG0508@1|root,COG0508@2|Bacteria,1MVDC@1224|Proteobacteria,1RQ9Y@1236|Gammaproteobacteria,4657Y@72275|Alteromonadaceae 1236|Gammaproteobacteria C 2-oxoacid dehydrogenases acyltransferase (catalytic domain) pdhC - 2.3.1.12,2.3.1.168 ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 M00036,M00307 R00209,R02569,R02662,R03174,R04097,R10998 RC00004,RC02727,RC02742,RC02857,RC02870 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding k141_28531_2 1453501.JELR01000002_gene1140 3.79e-61 197.0 COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,1RP3G@1236|Gammaproteobacteria,465NK@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit pdhB - 1.2.4.1 ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C k141_30780_1 223926.28809558 6.96e-237 680.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1XSPS@135623|Vibrionales 135623|Vibrionales U COG0841 Cation multidrug efflux pump acrF - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran k141_15415_1 1123054.KB907713_gene593 3.34e-17 77.0 COG5645@1|root,COG5645@2|Bacteria,1NJDD@1224|Proteobacteria,1SGGJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF1375) - - - - - - - - - - - - DUF1375 k141_15415_2 392500.Swoo_4495 1.14e-53 179.0 COG2819@1|root,COG2819@2|Bacteria,1RB1X@1224|Proteobacteria,1RY80@1236|Gammaproteobacteria,2QBJQ@267890|Shewanellaceae 1236|Gammaproteobacteria S Putative esterase - - - ko:K07017 - - - - ko00000 - - - Esterase k141_30781_1 1042377.AFPJ01000042_gene1030 1.45e-131 385.0 COG1653@1|root,COG1653@2|Bacteria,1MUNZ@1224|Proteobacteria,1RP01@1236|Gammaproteobacteria,465XT@72275|Alteromonadaceae 1236|Gammaproteobacteria G ABC-type sugar transport system, periplasmic component mtlE - - ko:K10227 ko02010,map02010 M00200 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.5 - - SBP_bac_1 k141_8304_1 218284.CCDN010000001_gene940 2.34e-113 334.0 COG0404@1|root,COG0404@2|Bacteria,1TRKX@1239|Firmicutes,4H9MX@91061|Bacilli,1ZAS5@1386|Bacillus 91061|Bacilli E The glycine cleavage system catalyzes the degradation of glycine gcvT - 2.1.2.10 ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 M00532 R01221,R02300,R04125 RC00022,RC00069,RC00183,RC02834 ko00000,ko00001,ko00002,ko01000 - - - GCV_T,GCV_T_C k141_28534_1 218284.CCDN010000002_gene2892 4.39e-122 356.0 COG0492@1|root,COG0492@2|Bacteria,1TRPN@1239|Firmicutes,4HACJ@91061|Bacilli,1ZB05@1386|Bacillus 91061|Bacilli C Ferredoxin--NADP reductase - - 1.18.1.2,1.19.1.1 ko:K21567 - - - - ko00000,ko01000 - - - Pyr_redox_2,Pyr_redox_3 k141_36763_1 314292.VAS14_04428 6.12e-45 151.0 2AWNV@1|root,31NJN@2|Bacteria,1QKAC@1224|Proteobacteria,1TIDW@1236|Gammaproteobacteria,1XYYB@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_36764_1 272943.RSP_3210 7.07e-92 278.0 COG1294@1|root,COG1294@2|Bacteria,1MURP@1224|Proteobacteria,2TU3I@28211|Alphaproteobacteria,1FC24@1060|Rhodobacter 28211|Alphaproteobacteria C Cytochrome bd terminal oxidase subunit II cydB - 1.10.3.14 ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - Cyt_bd_oxida_II k141_15417_1 411469.EUBHAL_01942 2.46e-22 94.0 COG0299@1|root,COG0299@2|Bacteria,1V3RJ@1239|Firmicutes,249JC@186801|Clostridia,25VE7@186806|Eubacteriaceae 186801|Clostridia F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate purN - 2.1.2.2 ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04325,R04326 RC00026,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 - - iHN637.CLJU_RS04225 Formyl_trans_N k141_8306_1 1033734.CAET01000027_gene882 5.92e-102 333.0 COG2909@1|root,COG3629@1|root,COG2909@2|Bacteria,COG3629@2|Bacteria,1UWHI@1239|Firmicutes,4HADH@91061|Bacilli,1ZE89@1386|Bacillus 91061|Bacilli KT COG2909 ATP-dependent transcriptional regulator - - - ko:K03556 - - - - ko00000,ko03000 - - - AAA_16,BTAD,TPR_12,TPR_8 k141_30784_1 1042377.AFPJ01000034_gene2328 1.63e-24 105.0 COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,1RMY0@1236|Gammaproteobacteria,4642B@72275|Alteromonadaceae 1236|Gammaproteobacteria K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released rpoN GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0042802,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - ko:K03092 ko02020,ko05111,map02020,map05111 - - - ko00000,ko00001,ko03021 - - - Sigma54_AID,Sigma54_CBD,Sigma54_DBD k141_7142_2 574375.BAGA_22130 1.34e-148 425.0 COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,4HBQY@91061|Bacilli,1ZEAK@1386|Bacillus 91061|Bacilli EP Binding-protein-dependent transport system inner membrane component - - - ko:K15585 ko02010,map02010 M00440 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 k141_3581_1 218284.CCDN010000002_gene2256 2.39e-25 102.0 COG0477@1|root,COG0477@2|Bacteria,1UIJV@1239|Firmicutes,4ISKN@91061|Bacilli,1ZS6S@1386|Bacillus 91061|Bacilli EGP COG0477 Permeases of the major facilitator superfamily yfkF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - MFS_1,MFS_1_like k141_3581_2 218284.CCDN010000002_gene2257 1.72e-71 216.0 COG1765@1|root,COG1765@2|Bacteria,1V78R@1239|Firmicutes,4HMM3@91061|Bacilli,1ZH2T@1386|Bacillus 91061|Bacilli O OsmC-like protein - - - - - - - - - - - - OsmC k141_35675_1 1117108.PAALTS15_11379 3.28e-87 264.0 COG0697@1|root,COG0697@2|Bacteria,1TR1G@1239|Firmicutes,4HB57@91061|Bacilli,26TFC@186822|Paenibacillaceae 91061|Bacilli EG of the drug metabolite transporter (DMT) superfamily - - - - - - - - - - - - EamA k141_21417_1 218284.CCDN010000001_gene1031 5.31e-158 449.0 COG0667@1|root,COG0667@2|Bacteria,1TTT8@1239|Firmicutes,4H9XM@91061|Bacilli,1ZBYV@1386|Bacillus 91061|Bacilli C oxidoreductases (related to aryl-alcohol dehydrogenases) yqkF - - - - - - - - - - - Aldo_ket_red k141_28544_1 1040989.AWZU01000008_gene3649 1.49e-40 148.0 COG0697@1|root,COG0697@2|Bacteria,1MXX1@1224|Proteobacteria,2VED8@28211|Alphaproteobacteria,3JWVQ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria EG EamA-like transporter family - - - - - - - - - - - - EamA k141_28544_2 106370.Francci3_4286 2.88e-10 65.5 COG0664@1|root,COG0664@2|Bacteria,2GMPN@201174|Actinobacteria,4ESG1@85013|Frankiales 201174|Actinobacteria K PFAM Cyclic nucleotide-binding glxR GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 - ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 - - - ko00000,ko00001,ko03000 - - - HTH_Crp_2,cNMP_binding k141_1196_1 1294265.JCM21738_4911 4.83e-56 181.0 COG4924@1|root,COG4924@2|Bacteria,1TRVG@1239|Firmicutes,4HB8B@91061|Bacilli,1ZERZ@1386|Bacillus 91061|Bacilli S Protein of unknown function N-terminus (DUF3323) - - - - - - - - - - - - DUF2399,DUF3323 k141_26167_1 218284.CCDN010000006_gene3623 2.5e-115 359.0 COG0457@1|root,COG0457@2|Bacteria,1TSH7@1239|Firmicutes,4HACN@91061|Bacilli,1ZBDH@1386|Bacillus 91061|Bacilli M Tetratricopeptide repeat - - - - - - - - - - - - - k141_15466_1 1453501.JELR01000001_gene2909 1.74e-73 232.0 2C3QV@1|root,2Z7YP@2|Bacteria,1MXAM@1224|Proteobacteria,1RNIA@1236|Gammaproteobacteria,4662K@72275|Alteromonadaceae 1236|Gammaproteobacteria S Alginate export - - - - - - - - - - - - Alginate_exp k141_15466_2 1279017.AQYJ01000021_gene2795 0.0 1020.0 COG1164@1|root,COG1164@2|Bacteria,1MWYN@1224|Proteobacteria,1RS2Q@1236|Gammaproteobacteria,465UB@72275|Alteromonadaceae 1236|Gammaproteobacteria E Angiotensin-converting enzyme - - 3.4.15.1 ko:K01283 ko04614,ko04924,ko05142,ko05410,map04614,map04924,map05142,map05410 - - - ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 - - - Peptidase_M2 k141_33299_2 1042377.AFPJ01000025_gene606 1.02e-44 150.0 COG2413@1|root,COG2413@2|Bacteria,1QXNS@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_34489_2 1501230.ET33_05035 9.88e-42 145.0 COG3153@1|root,COG3153@2|Bacteria,1V3PW@1239|Firmicutes,4HGZK@91061|Bacilli,26XET@186822|Paenibacillaceae 91061|Bacilli S GCN5 family acetyltransferase - - - ko:K03824 - - - - ko00000,ko01000 - - - Acetyltransf_1,Acetyltransf_9 k141_34489_3 1460635.JCM19038_2127 1.98e-17 78.2 COG0454@1|root,COG0456@2|Bacteria,1V64S@1239|Firmicutes,4HH30@91061|Bacilli 91061|Bacilli K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - - - - - - - - - - Acetyltransf_1 k141_3582_1 911045.PSE_4557 3.66e-104 311.0 COG1124@1|root,COG1124@2|Bacteria,1MUGH@1224|Proteobacteria,2TTGA@28211|Alphaproteobacteria 28211|Alphaproteobacteria EP ABC transporter - - - ko:K02032 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - ABC_tran k141_26168_1 1294265.JCM21738_184 2.11e-53 177.0 COG0116@1|root,COG0116@2|Bacteria,1TP0X@1239|Firmicutes,4HBKY@91061|Bacilli,1ZBJB@1386|Bacillus 91061|Bacilli L Belongs to the methyltransferase superfamily ypsC GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 - ko:K07444 - - - - ko00000,ko01000 - - - THUMP,UPF0020 k141_2389_1 1385511.N783_16750 2.82e-61 212.0 COG0454@1|root,COG0456@2|Bacteria,1TQQA@1239|Firmicutes,4HBXN@91061|Bacilli,2YBGI@289201|Pontibacillus 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10 k141_19031_2 1279017.AQYJ01000021_gene2847 6.29e-65 203.0 COG0350@1|root,COG0350@2|Bacteria,1N2YQ@1224|Proteobacteria,1S68H@1236|Gammaproteobacteria,467W5@72275|Alteromonadaceae 1236|Gammaproteobacteria L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated ogt - 2.1.1.63 ko:K00567 - - - - ko00000,ko01000,ko03400 - - - DNA_binding_1,Methyltransf_1N k141_16_1 1294265.JCM21738_3698 8.57e-10 64.3 COG0852@1|root,COG0852@2|Bacteria,1UFNI@1239|Firmicutes,4HDV1@91061|Bacilli,1ZB7U@1386|Bacillus 91061|Bacilli C COG0852 NADH ubiquinone oxidoreductase 27 kD subunit nuoC - 1.6.5.3 ko:K00332 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_30kDa k141_17839_1 1379270.AUXF01000002_gene1153 1.14e-28 113.0 COG1595@1|root,COG1595@2|Bacteria 2|Bacteria K DNA-templated transcription, initiation sigZ - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_17839_2 1268622.AVS7_02314 2.42e-42 145.0 COG0346@1|root,COG0346@2|Bacteria,1RHIV@1224|Proteobacteria,2VQPS@28216|Betaproteobacteria,4AEAA@80864|Comamonadaceae 28216|Betaproteobacteria E PFAM Glyoxalase bleomycin resistance protein dioxygenase cadI - 4.4.1.5 ko:K01759 ko00620,map00620 - R02530 RC00004,RC00740 ko00000,ko00001,ko01000 - - - Glyoxalase k141_28546_1 1117108.PAALTS15_22313 4.11e-21 92.0 COG1670@1|root,COG1670@2|Bacteria,1V1CU@1239|Firmicutes,4HGJ4@91061|Bacilli,274T1@186822|Paenibacillaceae 91061|Bacilli J (GNAT) family - - 2.3.1.128 ko:K03790 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 k141_11898_1 391615.ABSJ01000026_gene84 1.3e-77 245.0 COG0538@1|root,COG0538@2|Bacteria,1MW3J@1224|Proteobacteria,1RNMD@1236|Gammaproteobacteria,1J4Z7@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Isocitrate icd GO:0003674,GO:0003824,GO:0004448,GO:0004450,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0022900,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0055114 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 - - e_coli_core.b1136,iAF1260.b1136,iECDH1ME8569_1439.ECDH1ME8569_1071,iEcDH1_1363.EcDH1_2511,iJN746.PP_4011,iJO1366.b1136,iJR904.b1136,iY75_1357.Y75_RS05930,iYL1228.KPN_01144 Iso_dh k141_21419_1 42565.FP66_05555 1.3e-62 199.0 COG0702@1|root,COG0702@2|Bacteria,1MW54@1224|Proteobacteria 1224|Proteobacteria GM Epimerase dehydratase - - 1.6.5.3,1.6.99.3 ko:K00329,ko:K00356 ko00190,map00190 - R11945 RC00061 ko00000,ko00001,ko01000 - - - 3Beta_HSD,Epimerase,NAD_binding_10,RmlD_sub_bind k141_5957_2 1042377.AFPJ01000030_gene447 0.0 1006.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MV8W@1224|Proteobacteria,1RMQA@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Outer membrane receptor proteins mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec k141_26169_2 218284.CCDN010000005_gene3291 2.31e-75 242.0 COG1164@1|root,COG1164@2|Bacteria,1TP4P@1239|Firmicutes,4HA7X@91061|Bacilli,1ZCHA@1386|Bacillus 91061|Bacilli E oligoendopeptidase F pepF GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - ko:K08602 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M3,Peptidase_M3_N k141_2390_2 218284.CCDN010000001_gene189 1.86e-31 111.0 2F8H8@1|root,3082J@2|Bacteria,1U2PE@1239|Firmicutes,4ICCB@91061|Bacilli,1ZK9K@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_17_2 1453501.JELR01000001_gene2599 5.2e-45 149.0 COG3453@1|root,COG3453@2|Bacteria 2|Bacteria J Protein conserved in bacteria blh - 1.8.5.4 ko:K17218 ko00920,map00920 - R10152 RC03155 ko00000,ko00001,ko01000 - - - DUF442,Pyr_redox_2 k141_24973_1 218284.CCDN010000005_gene3334 1.19e-90 288.0 COG0209@1|root,COG0209@2|Bacteria,1TPFH@1239|Firmicutes,4H9X0@91061|Bacilli,1ZANT@1386|Bacillus 91061|Bacilli F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdA - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN k141_26170_1 42565.FP66_04895 1.92e-16 76.6 COG1024@1|root,COG1024@2|Bacteria,1MVEC@1224|Proteobacteria,1RP85@1236|Gammaproteobacteria,1XHW2@135619|Oceanospirillales 135619|Oceanospirillales I enoyl-CoA hydratase - - 4.2.1.18 ko:K13766 ko00280,ko01100,map00280,map01100 M00036 R02085 RC02416 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 k141_33300_1 42565.FP66_11770 9.29e-32 113.0 COG1671@1|root,COG1671@2|Bacteria,1RCZA@1224|Proteobacteria,1S3QM@1236|Gammaproteobacteria,1XJUV@135619|Oceanospirillales 135619|Oceanospirillales S Belongs to the UPF0178 family - - - ko:K09768 - - - - ko00000 - - - DUF188 k141_33300_2 1118153.MOY_01674 0.000248 42.4 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1XIKF@135619|Oceanospirillales 135619|Oceanospirillales L DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation deaD - 3.6.4.13 ko:K05592 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,DbpA,Helicase_C k141_8342_1 1285586.H131_20332 2.74e-27 102.0 2ERT6@1|root,33JCD@2|Bacteria,1VNGD@1239|Firmicutes,4HRHI@91061|Bacilli,3IYR7@400634|Lysinibacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_8342_2 1295642.H839_10278 2.15e-30 114.0 2EJRY@1|root,33DGQ@2|Bacteria,1VK9E@1239|Firmicutes,4HRSA@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - k141_1197_1 479434.Sthe_3148 4.14e-49 169.0 COG0428@1|root,COG0428@2|Bacteria,2G9IR@200795|Chloroflexi 200795|Chloroflexi P transporter - - - - - - - - - - - - - k141_1197_2 1121346.KB899809_gene3598 7.01e-21 90.1 COG2132@1|root,COG2132@2|Bacteria,1V169@1239|Firmicutes,4HEK4@91061|Bacilli,26V87@186822|Paenibacillaceae 91061|Bacilli Q Multicopper oxidase - - - - - - - - - - - - Cu-oxidase_2,Cu-oxidase_3 k141_28548_2 935836.JAEL01000011_gene5213 1.53e-49 158.0 COG4471@1|root,COG4471@2|Bacteria,1VF52@1239|Firmicutes,4HNTH@91061|Bacilli,1ZI4I@1386|Bacillus 91061|Bacilli S UPF0298 protein ylbG - - - - - - - - - - - DUF2129 k141_9520_1 1453501.JELR01000002_gene844 2.75e-273 752.0 COG1904@1|root,COG1904@2|Bacteria,1MVRI@1224|Proteobacteria,1RMRR@1236|Gammaproteobacteria,464VQ@72275|Alteromonadaceae 1236|Gammaproteobacteria G Glucuronate isomerase uxaC GO:0005975,GO:0005996,GO:0006063,GO:0006064,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0019585,GO:0019586,GO:0019698,GO:0019752,GO:0032787,GO:0042839,GO:0042840,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046365,GO:0046395,GO:0046396,GO:0046397,GO:0071704,GO:0072329,GO:1901575 5.3.1.12 ko:K01812 ko00040,ko01100,map00040,map01100 M00061,M00631 R01482,R01983 RC00376 ko00000,ko00001,ko00002,ko01000 - - iPC815.YPO0579,iSbBS512_1146.SbBS512_E3528 UxaC k141_35677_2 935836.JAEL01000021_gene1495 4.93e-25 100.0 2DPCU@1|root,331IS@2|Bacteria,1VFIK@1239|Firmicutes,4HPAM@91061|Bacilli,1ZMPF@1386|Bacillus 91061|Bacilli S Phage minor structural protein GP20 - - - - - - - - - - - - Phage_GP20 k141_10708_1 218284.CCDN010000002_gene1999 0.0 1114.0 COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,4HB12@91061|Bacilli,1ZCM9@1386|Bacillus 91061|Bacilli L ATP-dependent DNA helicase pcrA - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C k141_15469_2 272942.RCAP_rcc03385 8.41e-52 181.0 COG0477@1|root,COG2814@2|Bacteria,1MU1I@1224|Proteobacteria,2TVXT@28211|Alphaproteobacteria,1FB3T@1060|Rhodobacter 28211|Alphaproteobacteria P TIGRFAM drug resistance transporter, EmrB QacA subfamily emrB - - ko:K03446 - M00701 - - ko00000,ko00002,ko02000 2.A.1.3 - - MFS_1 k141_18_1 76636.JOEC01000002_gene2395 0.00056 45.4 COG1175@1|root,COG1175@2|Bacteria,2GMTW@201174|Actinobacteria,4FNE7@85023|Microbacteriaceae 201174|Actinobacteria G Binding-protein-dependent transport system inner membrane component - - - ko:K02025 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - BPD_transp_1 k141_18_2 198467.NP92_05160 1.77e-45 158.0 COG1653@1|root,COG1653@2|Bacteria,1TQ0V@1239|Firmicutes,4HA7Z@91061|Bacilli,21WMI@150247|Anoxybacillus 91061|Bacilli G Bacterial extracellular solute-binding protein lacE - - ko:K10188 ko02010,map02010 M00199 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.4 - - SBP_bac_8 k141_4772_1 42565.FP66_06925 6.73e-150 439.0 COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,1RMY5@1236|Gammaproteobacteria,1XHYK@135619|Oceanospirillales 135619|Oceanospirillales O Cytochrome c-type biogenesis protein ccmF - - ko:K02198 - - - - ko00000,ko02000 9.B.14.1 - - CcmF_C,Cytochrom_C_asm k141_17840_1 1292035.H476_3335 2.11e-48 167.0 COG0667@1|root,COG0667@2|Bacteria,1V53W@1239|Firmicutes,24KNB@186801|Clostridia 186801|Clostridia C Aldo/keto reductase family - - - - - - - - - - - - Aldo_ket_red k141_7144_1 1042377.AFPJ01000053_gene1519 6.23e-165 473.0 COG1012@1|root,COG1012@2|Bacteria,1MUHV@1224|Proteobacteria,1RNFN@1236|Gammaproteobacteria,465NX@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1012 NAD-dependent aldehyde dehydrogenases mmsA - 1.2.1.18,1.2.1.27 ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 M00013 R00705,R00706,R00922,R00935 RC00004,RC02723,RC02817 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_27357_1 218284.CCDN010000008_gene4223 1.57e-109 337.0 COG0849@1|root,COG0849@2|Bacteria,1TP1Z@1239|Firmicutes,4HBAG@91061|Bacilli,1ZBRW@1386|Bacillus 91061|Bacilli D Cell division protein FtsA ftsA_1 - - - - - - - - - - - FtsA,PilM_2 k141_27357_2 333138.LQ50_13575 7.69e-08 54.3 COG1605@1|root,COG2876@1|root,COG1605@2|Bacteria,COG2876@2|Bacteria,1TP61@1239|Firmicutes,4HB03@91061|Bacilli,1ZB0X@1386|Bacillus 91061|Bacilli E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate aroA - 2.5.1.54,5.4.99.5 ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022,M00024,M00025 R01715,R01826 RC00435,RC03116 ko00000,ko00001,ko00002,ko01000 - - - CM_2,DAHP_synth_1 k141_5960_3 1196031.ALEG01000013_gene23 4.3e-21 91.3 COG0477@1|root,COG2814@2|Bacteria,1TRZB@1239|Firmicutes,4HC28@91061|Bacilli,1ZD6T@1386|Bacillus 91061|Bacilli EGP Transmembrane secretion effector ykuC1 - - ko:K08217 - - - - br01600,ko00000,ko01504,ko02000 2.A.1.21.1,2.A.1.21.22 - - MFS_1,MFS_3 k141_3586_1 1294265.JCM21738_285 1.71e-137 407.0 COG0550@1|root,COG0550@2|Bacteria,1TPUS@1239|Firmicutes,4HA6C@91061|Bacilli,1ZB7D@1386|Bacillus 91061|Bacilli L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topA - 5.99.1.2 ko:K03168 - - - - ko00000,ko01000,ko03032,ko03400 - - - Topoisom_bac,Toprim,zf-C4_Topoisom k141_2393_1 218284.CCDN010000004_gene3150 3.06e-59 194.0 COG0189@1|root,COG0189@2|Bacteria,1UZ79@1239|Firmicutes,4HTI1@91061|Bacilli,1ZBQZ@1386|Bacillus 91061|Bacilli HJ COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase) - - - - - - - - - - - - ATPgrasp_YheCD k141_2393_2 1461580.CCAS010000055_gene3731 2.7e-21 92.4 COG0189@1|root,COG0189@2|Bacteria,1TSWS@1239|Firmicutes,4HCJA@91061|Bacilli,1ZAR6@1386|Bacillus 91061|Bacilli HJ YheC/D like ATP-grasp yheD GO:0005575,GO:0005623,GO:0042601,GO:0042763,GO:0044464 - - - - - - - - - - ATPgrasp_YheCD k141_34490_2 1453501.JELR01000001_gene3219 1.76e-166 471.0 COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,1RTDE@1236|Gammaproteobacteria,464ZV@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG0846 NAD-dependent protein deacetylases, SIR2 family cobB - - ko:K12410 - - - - ko00000,ko01000 - - - SIR2 k141_19_1 1042377.AFPJ01000015_gene1612 8.17e-83 268.0 COG1199@1|root,COG1199@2|Bacteria,1MVRJ@1224|Proteobacteria,1RQ7B@1236|Gammaproteobacteria,464G6@72275|Alteromonadaceae 1236|Gammaproteobacteria KL COG1199 Rad3-related DNA helicases - - 3.6.4.12 ko:K10844 ko03022,ko03420,map03022,map03420 M00290 - - ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - DEAD_2,Helicase_C_2 k141_22717_3 1279017.AQYJ01000028_gene2063 5.31e-23 97.4 COG1300@1|root,COG1300@2|Bacteria,1Q1GN@1224|Proteobacteria,1RR61@1236|Gammaproteobacteria,466VE@72275|Alteromonadaceae 1236|Gammaproteobacteria S Stage II sporulation protein M - - - - - - - - - - - - SpoIIM k141_29814_1 1434325.AZQN01000003_gene2169 1.71e-27 116.0 COG3975@1|root,COG3975@2|Bacteria,4NGTY@976|Bacteroidetes,47JI8@768503|Cytophagia 976|Bacteroidetes S protease with the C-terminal PDZ domain - - - - - - - - - - - - Peptidase_M61 k141_6084_1 42565.FP66_02560 9.05e-176 493.0 COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,1RN65@1236|Gammaproteobacteria,1XHMA@135619|Oceanospirillales 135619|Oceanospirillales K Belongs to the ParB family parB - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc k141_157_2 1380358.JADJ01000007_gene2932 7.78e-05 43.9 2DQKB@1|root,337EE@2|Bacteria,1NC2T@1224|Proteobacteria,1SDTD@1236|Gammaproteobacteria,1XMRI@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF1656) - - - - - - - - - - - - DUF1656 k141_157_3 690597.JH730929_gene1820 3.3e-07 56.2 COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,1RMI7@1236|Gammaproteobacteria,1YMR5@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family mexE - - ko:K18298 - M00641 - - ko00000,ko00002,ko01504,ko02000 8.A.1 - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 k141_3700_1 218284.CCDN010000009_gene4274 4.72e-179 501.0 COG1624@1|root,COG1624@2|Bacteria,1TPRW@1239|Firmicutes,4H9XZ@91061|Bacilli,1ZBIU@1386|Bacillus 91061|Bacilli S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria dacA GO:0003674,GO:0003824,GO:0004016,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0009975,GO:0016020,GO:0016021,GO:0016829,GO:0016849,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 2.7.7.85 ko:K18672 - - - - ko00000,ko01000 - - - DisA_N k141_13225_1 420246.GTNG_2872 4.36e-06 50.1 COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,4HAFP@91061|Bacilli,1WFVR@129337|Geobacillus 91061|Bacilli V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family swrC - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran k141_13225_2 1279017.AQYJ01000028_gene2397 1.64e-96 282.0 COG1267@1|root,COG1267@2|Bacteria,1MZJA@1224|Proteobacteria,1S68A@1236|Gammaproteobacteria,467H1@72275|Alteromonadaceae 1236|Gammaproteobacteria I Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) pgpA GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008962,GO:0009058,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0030258,GO:0031224,GO:0031226,GO:0032026,GO:0042221,GO:0042577,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0046839,GO:0050896,GO:0071704,GO:0071944,GO:0090407,GO:1901576 3.1.3.27 ko:K01095 ko00564,ko01100,map00564,map01100 - R02029 RC00017 ko00000,ko00001,ko01000 - - iECSP_1301.ECSP_0485,iECUMN_1333.ECUMN_0456,iECs_1301.ECs0471,iG2583_1286.G2583_0529,iPC815.YPO3179,iZ_1308.Z0520 PgpA k141_13225_3 1042377.AFPJ01000024_gene714 2.86e-99 293.0 COG3577@1|root,COG3577@2|Bacteria,1N2PE@1224|Proteobacteria,1S66F@1236|Gammaproteobacteria,467QR@72275|Alteromonadaceae 1236|Gammaproteobacteria S gag-polyprotein putative aspartyl protease - - - ko:K06985 ko04112,map04112 - - - ko00000,ko00001 - - - gag-asp_proteas k141_13225_4 1453501.JELR01000002_gene536 2.04e-127 364.0 COG0807@1|root,COG0807@2|Bacteria,1MWZR@1224|Proteobacteria,1RMFX@1236|Gammaproteobacteria,465AE@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate ribA GO:0003674,GO:0003824,GO:0003933,GO:0003935,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019238,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.5.4.25 ko:K01497 ko00740,ko00790,ko01100,ko01110,ko02024,map00740,map00790,map01100,map01110,map02024 M00125 R00425 RC00293,RC02504 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_437,iPC815.YPO2222,iSbBS512_1146.SbBS512_E1505,iUTI89_1310.UTI89_C1548 GTP_cyclohydro2 k141_13225_5 1279017.AQYJ01000028_gene2401 0.0 1605.0 COG1523@1|root,COG1523@2|Bacteria,1MU19@1224|Proteobacteria,1RP6F@1236|Gammaproteobacteria,465SK@72275|Alteromonadaceae 1236|Gammaproteobacteria G Belongs to the glycosyl hydrolase 13 family pulA - 3.2.1.41 ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 - R02111 - ko00000,ko00001,ko01000 - CBM48,GH13 - Alpha-amylase,CBM_48,DUF3372,PUD k141_15607_1 1453501.JELR01000001_gene2508 8.79e-61 209.0 28IUR@1|root,2Z8TE@2|Bacteria,1NW7C@1224|Proteobacteria,1RP4W@1236|Gammaproteobacteria,465G0@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_20290_1 42565.FP66_07450 5.87e-130 379.0 COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,1RMU8@1236|Gammaproteobacteria,1XI27@135619|Oceanospirillales 135619|Oceanospirillales G phosphomannomutase algC - 5.4.2.2,5.4.2.8 ko:K15778 ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00114 R00959,R01057,R01818,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV k141_23860_1 218284.CCDN010000003_gene2991 5.45e-132 391.0 COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,4HACG@91061|Bacilli,1ZBBF@1386|Bacillus 91061|Bacilli S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid yabM GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03328 - - - - ko00000 2.A.66.2 - - Polysacc_synt,Polysacc_synt_C k141_31044_1 1285586.H131_03504 5.78e-50 168.0 COG1737@1|root,COG1737@2|Bacteria,1TPIX@1239|Firmicutes,4HBJA@91061|Bacilli,3IXCF@400634|Lysinibacillus 91061|Bacilli K Helix-turn-helix domain, rpiR family ybbH GO:0003674,GO:0003700,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 - - - - - - - - - - HTH_6,SIS k141_34603_1 941449.dsx2_2467 8.97e-62 211.0 COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,42M70@68525|delta/epsilon subdivisions,2WJA8@28221|Deltaproteobacteria,2M7ZN@213115|Desulfovibrionales 28221|Deltaproteobacteria J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain alaS GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DHHA1,tRNA-synt_2c,tRNA_SAD k141_13226_2 218284.CCDN010000004_gene3092 6.16e-23 95.9 COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,1TR88@1239|Firmicutes,4HBF3@91061|Bacilli,1ZCMJ@1386|Bacillus 91061|Bacilli T Histidine kinase yhcY - 2.7.13.3 ko:K02480 - - - - ko00000,ko01000,ko01001,ko02022 - - - GAF_2,HATPase_c,HisKA_3 k141_2506_1 218284.CCDN010000001_gene972 2.89e-159 451.0 COG1189@1|root,COG1189@2|Bacteria,1TPE4@1239|Firmicutes,4HAPY@91061|Bacilli,1ZBDS@1386|Bacillus 91061|Bacilli J rRNA methylase rrmJ - 2.1.1.226,2.1.1.227 ko:K06442 - - - - ko00000,ko01000,ko03009 - - - FtsJ,S4 k141_29816_1 1423321.AS29_15615 2e-44 147.0 COG3795@1|root,COG3795@2|Bacteria,1VDPN@1239|Firmicutes,4HKKT@91061|Bacilli,1ZH8J@1386|Bacillus 91061|Bacilli S YCII-related domain - - - - - - - - - - - - YCII k141_36933_2 42565.FP66_06570 1.12e-102 298.0 COG0097@1|root,COG0097@2|Bacteria,1R9YZ@1224|Proteobacteria,1S1Z1@1236|Gammaproteobacteria,1XJA3@135619|Oceanospirillales 135619|Oceanospirillales J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center rplF - - ko:K02933 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L6 k141_13227_1 218284.CCDN010000002_gene2947 1.36e-119 345.0 COG4587@1|root,COG4587@2|Bacteria,1TSAN@1239|Firmicutes,4HBVU@91061|Bacilli,1ZBKH@1386|Bacillus 91061|Bacilli S ABC transporter (permease) M1-956 - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_6 k141_11989_1 218284.CCDN010000005_gene3353 4.67e-85 278.0 COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,4HAFP@91061|Bacilli,1ZBJ3@1386|Bacillus 91061|Bacilli V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran k141_32179_1 1121403.AUCV01000001_gene731 1.05e-16 80.1 COG3067@1|root,COG3067@2|Bacteria,1MV0F@1224|Proteobacteria,42YU7@68525|delta/epsilon subdivisions,2WUC4@28221|Deltaproteobacteria,2MMM7@213118|Desulfobacterales 28221|Deltaproteobacteria P Bacterial Na+/H+ antiporter B (NhaB) - - - ko:K03314 - - - - ko00000,ko02000 2.A.34.1 - - NhaB k141_3701_1 218284.CCDN010000001_gene180 1.43e-89 268.0 COG0730@1|root,COG0730@2|Bacteria,1TQBK@1239|Firmicutes,4HBCW@91061|Bacilli,1ZCK1@1386|Bacillus 91061|Bacilli S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE k141_3701_2 218284.CCDN010000001_gene179 1.07e-136 391.0 COG0583@1|root,COG0583@2|Bacteria,1TZ6U@1239|Firmicutes,4HB3Y@91061|Bacilli,1ZB8N@1386|Bacillus 91061|Bacilli K Transcriptional regulator ccpC - - - - - - - - - - - HTH_1,LysR_substrate k141_6088_1 935836.JAEL01000002_gene539 6.58e-35 127.0 COG1191@1|root,COG1191@2|Bacteria,1TP9K@1239|Firmicutes,4HCJV@91061|Bacilli,1ZAPF@1386|Bacillus 91061|Bacilli K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released sigD - - ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 - - - ko00000,ko00001,ko02035,ko03021 - - - Sigma70_r2,Sigma70_r3,Sigma70_r4 k141_6088_2 1196031.ALEG01000039_gene1688 2.94e-15 75.9 2D5MU@1|root,32TJF@2|Bacteria,1V9ZA@1239|Firmicutes,4HMQI@91061|Bacilli,1ZFEI@1386|Bacillus 91061|Bacilli - - ylxL - - - - - - - - - - - - k141_35753_1 218284.CCDN010000002_gene2155 5.55e-125 364.0 COG1309@1|root,COG1309@2|Bacteria,1UDHR@1239|Firmicutes,4HFAX@91061|Bacilli,1ZFND@1386|Bacillus 91061|Bacilli K Transcriptional regulator yerO GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 - - - - - - - - - - TetR_N k141_17987_1 558169.AGAV01000016_gene969 0.000226 45.1 COG1158@1|root,COG1158@2|Bacteria,1TPHZ@1239|Firmicutes,4H9XB@91061|Bacilli 91061|Bacilli K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template rho - - ko:K03628 ko03018,map03018 - - - ko00000,ko00001,ko03019,ko03021 - - - ATP-synt_ab,Rho_N,Rho_RNA_bind k141_7229_2 1294265.JCM21738_1269 5.02e-79 238.0 COG0348@1|root,COG0348@2|Bacteria,1VPU2@1239|Firmicutes,4HZRI@91061|Bacilli 91061|Bacilli C 4Fe-4S binding domain - - - - - - - - - - - - Fer4_5 k141_29817_1 218284.CCDN010000002_gene2816 1.17e-37 135.0 COG2367@1|root,COG2367@2|Bacteria,1V2JD@1239|Firmicutes,4HGP1@91061|Bacilli,1ZD4B@1386|Bacillus 91061|Bacilli V Beta-lactamase enzyme family - - 3.4.16.4 ko:K01286 - - - - ko00000,ko01000 - - - Beta-lactamase2 k141_29817_2 218284.CCDN010000002_gene2817 8.74e-51 170.0 2CDJQ@1|root,2Z7JX@2|Bacteria,1TR73@1239|Firmicutes,4HAT1@91061|Bacilli,1ZRA6@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_22718_1 218284.CCDN010000001_gene1331 4.58e-121 355.0 COG0508@1|root,COG0508@2|Bacteria,1TP3C@1239|Firmicutes,4HBVM@91061|Bacilli,1ZBCB@1386|Bacillus 91061|Bacilli C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) odhB - 2.3.1.61 ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R02570,R02571,R08549 RC00004,RC02727,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding k141_34604_1 1453501.JELR01000001_gene3016 5.86e-36 132.0 COG1426@1|root,COG1426@2|Bacteria,1N240@1224|Proteobacteria,1RQMV@1236|Gammaproteobacteria,4689I@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria rodZ GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944 - ko:K15539 - - - - ko00000 - - - DUF4115,HTH_25 k141_32180_1 1034347.CAHJ01000048_gene220 9.67e-32 125.0 COG1595@1|root,COG1595@2|Bacteria,1U9I0@1239|Firmicutes,4IJNF@91061|Bacilli,1ZC9D@1386|Bacillus 91061|Bacilli K Domain of unknown function (DUF4179) - - - - - - - - - - - - DUF4179,Sigma70_r4,Sigma70_r4_2,zf-HC2 k141_159_2 1453501.JELR01000002_gene1013 1.13e-210 599.0 COG2176@1|root,COG2176@2|Bacteria,1MUZD@1224|Proteobacteria,1RPGP@1236|Gammaproteobacteria,4645Z@72275|Alteromonadaceae 1236|Gammaproteobacteria L VRR_NUC - - - - - - - - - - - - VRR_NUC k141_31046_1 986075.CathTA2_0972 1.1e-142 428.0 COG0046@1|root,COG0046@2|Bacteria,1TPAS@1239|Firmicutes,4HB3N@91061|Bacilli 91061|Bacilli F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL purL - 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C k141_22719_1 218284.CCDN010000002_gene2106 4.67e-05 44.7 COG1071@1|root,COG1071@2|Bacteria,1TQDG@1239|Firmicutes,4H9PR@91061|Bacilli,1ZARF@1386|Bacillus 91061|Bacilli C Dehydrogenase E1 component - - 1.2.4.1 ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh k141_3703_1 1461580.CCAS010000059_gene3843 6.21e-28 115.0 COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,4HA31@91061|Bacilli,1ZB6P@1386|Bacillus 91061|Bacilli O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain htrA - 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Trypsin_2 k141_27424_1 555779.Dthio_PD2605 9.04e-69 225.0 COG3039@1|root,COG3039@2|Bacteria,1QQ9Q@1224|Proteobacteria,42S7X@68525|delta/epsilon subdivisions,2WNJ2@28221|Deltaproteobacteria 28221|Deltaproteobacteria L PFAM transposase, IS4 family protein - - - - - - - - - - - - DDE_Tnp_1,DUF772 k141_2508_1 218284.CCDN010000001_gene1113 1.49e-147 419.0 COG1352@1|root,COG1352@2|Bacteria,1TPD8@1239|Firmicutes,4HAS1@91061|Bacilli,1ZCKU@1386|Bacillus 91061|Bacilli NT COG1352 Methylase of chemotaxis methyl-accepting proteins cheR - 2.1.1.80 ko:K00575 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko01000,ko02035 - - - CheR,CheR_N k141_14400_1 1279017.AQYJ01000020_gene1285 5.86e-269 766.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,464AK@72275|Alteromonadaceae 1236|Gammaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran k141_14400_2 1453501.JELR01000002_gene875 3.28e-155 440.0 COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,1RMJJ@1236|Gammaproteobacteria,465VY@72275|Alteromonadaceae 1236|Gammaproteobacteria KT Response regulator of the LytR AlgR family - - - ko:K02477 - - - - ko00000,ko02022 - - - LytTR,Response_reg k141_14400_3 1042377.AFPJ01000043_gene879 2.94e-215 599.0 COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,1RQDA@1236|Gammaproteobacteria,465PG@72275|Alteromonadaceae 1236|Gammaproteobacteria T Histidine kinase - - 2.7.13.3 ko:K08082 ko02020,map02020 M00493 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,His_kinase k141_14400_4 1453501.JELR01000002_gene877 5.09e-76 230.0 COG2947@1|root,COG2947@2|Bacteria,1RHRU@1224|Proteobacteria,1S68X@1236|Gammaproteobacteria,467AM@72275|Alteromonadaceae 1236|Gammaproteobacteria S EVE domain - - - - - - - - - - - - EVE k141_14400_6 1279017.AQYJ01000020_gene1292 2.51e-118 343.0 COG0778@1|root,COG0778@2|Bacteria,1MY39@1224|Proteobacteria,1RS8B@1236|Gammaproteobacteria,46DGX@72275|Alteromonadaceae 1236|Gammaproteobacteria C Nitroreductase family - - - - - - - - - - - - Nitroreductase k141_14400_7 1453501.JELR01000002_gene878 8.43e-18 77.8 2EN5A@1|root,33FT9@2|Bacteria,1NH74@1224|Proteobacteria,1SHI0@1236|Gammaproteobacteria,46960@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF3094) - - - - - - - - - - - - DUF3094 k141_14400_8 1279017.AQYJ01000020_gene1295 0.0 1032.0 COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,1RNV1@1236|Gammaproteobacteria,466AQ@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1960 Acyl-CoA dehydrogenases - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N k141_14400_9 1279017.AQYJ01000020_gene1296 8.18e-121 349.0 COG0132@1|root,COG0132@2|Bacteria,1RDRK@1224|Proteobacteria,1RSHS@1236|Gammaproteobacteria,466IJ@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring bioD GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004141,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017076,GO:0017144,GO:0018130,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.3.3 ko:K01935 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R03182 RC00868 ko00000,ko00001,ko00002,ko01000 - - iEC55989_1330.EC55989_0821,iECIAI1_1343.ECIAI1_0813,iECO103_1326.ECO103_0813,iECO111_1330.ECO111_0839,iECO26_1355.ECO26_0904,iECSE_1348.ECSE_0831,iECW_1372.ECW_m0833,iEKO11_1354.EKO11_3108,iEcE24377_1341.EcE24377A_0841,iSFV_1184.SFV_0761,iSSON_1240.SSON_0757,iWFL_1372.ECW_m0833,ic_1306.c0858 AAA_26 k141_14400_10 1279017.AQYJ01000020_gene1297 9.66e-85 253.0 COG3034@1|root,COG3034@2|Bacteria,1MXY6@1224|Proteobacteria,1S66I@1236|Gammaproteobacteria,4682Y@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria IV02_27405 - - - - - - - - - - - YkuD k141_7230_1 1336233.JAEH01000001_gene702 9.55e-09 63.5 COG0500@1|root,COG2226@2|Bacteria,1N7M1@1224|Proteobacteria,1SCU6@1236|Gammaproteobacteria,2Q9WN@267890|Shewanellaceae 1236|Gammaproteobacteria Q ubiE/COQ5 methyltransferase family - - - - - - - - - - - - Methyltransf_25 k141_10785_1 1279017.AQYJ01000024_gene927 6.93e-230 649.0 COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,1RPNE@1236|Gammaproteobacteria,464ZH@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1022 Long-chain acyl-CoA synthetases (AMP-forming) - - - - - - - - - - - - AMP-binding k141_28678_3 218284.CCDN010000002_gene2017 1.64e-141 414.0 COG3227@1|root,COG3227@2|Bacteria,1TP08@1239|Firmicutes,4H9S6@91061|Bacilli,1ZCEP@1386|Bacillus 91061|Bacilli E Peptidase M4 npr GO:0005575,GO:0005576 3.4.24.28 ko:K01400 - - - - ko00000,ko01000,ko01002 - - - FTP,PepSY,Peptidase_M4,Peptidase_M4_C k141_34605_1 218284.CCDN010000004_gene3073 5.64e-136 391.0 COG1609@1|root,COG1609@2|Bacteria,1TQSQ@1239|Firmicutes,4HBNR@91061|Bacilli,1ZC0J@1386|Bacillus 91061|Bacilli K Transcriptional regulator ykvZ - - - - - - - - - - - LacI,Peripla_BP_1,Peripla_BP_3 k141_6137_2 218284.CCDN010000004_gene3154 1.22e-160 459.0 COG4399@1|root,COG4399@2|Bacteria,1TQDH@1239|Firmicutes,4HA30@91061|Bacilli,1ZB1W@1386|Bacillus 91061|Bacilli S Belongs to the UPF0754 family yheB - - - - - - - - - - - DUF445 k141_22740_2 1207075.PputUW4_02137 1.55e-43 144.0 COG3791@1|root,COG3791@2|Bacteria,1RCYS@1224|Proteobacteria,1S3X0@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Glutathione-dependent formaldehyde-activating enzyme - - - - - - - - - - - - GFA k141_23883_1 65393.PCC7424_1313 5.12e-45 154.0 COG2323@1|root,COG2323@2|Bacteria,1G5E3@1117|Cyanobacteria,3KHT6@43988|Cyanothece 1117|Cyanobacteria S Protein of unknown function (DUF421) - - - - - - - - - - - - DUF421 k141_26333_1 1294265.JCM21738_1724 2.99e-86 265.0 COG4129@1|root,COG4129@2|Bacteria,1TPVH@1239|Firmicutes,4HAEG@91061|Bacilli,1ZC8P@1386|Bacillus 91061|Bacilli S Fusaric acid resistance protein family ygaE - - - - - - - - - - - ArAE_1 k141_31087_1 1307436.PBF_17409 2.82e-135 385.0 COG2013@1|root,COG2013@2|Bacteria,1TSVH@1239|Firmicutes,4HD5V@91061|Bacilli,1ZCFB@1386|Bacillus 91061|Bacilli S Mitochondrial biogenesis AIM24 - - - - - - - - - - - - AIM24 k141_16777_1 881621.LIV_2178 7.12e-80 238.0 COG1393@1|root,COG1393@2|Bacteria,1V3QC@1239|Firmicutes,4HH0I@91061|Bacilli,26KJP@186820|Listeriaceae 91061|Bacilli K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress spxA - - ko:K16509 - - - - ko00000 - - - ArsC k141_3737_1 218284.CCDN010000008_gene4038 6.49e-108 324.0 COG2986@1|root,COG2986@2|Bacteria,1TPCW@1239|Firmicutes,4H9YS@91061|Bacilli,1ZC8Z@1386|Bacillus 91061|Bacilli E Histidine ammonia-lyase hutH - 4.3.1.3 ko:K01745 ko00340,ko01100,map00340,map01100 M00045 R01168 RC00361 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU39350 Lyase_aromatic k141_7269_1 218284.CCDN010000001_gene187 4.14e-236 656.0 COG2200@1|root,COG2200@2|Bacteria,1UADD@1239|Firmicutes,4HCNX@91061|Bacilli,1ZBWD@1386|Bacillus 91061|Bacilli T Diguanylate phosphodiesterase ykuI - - - - - - - - - - - EAL,YkuI_C k141_12017_1 1042377.AFPJ01000028_gene2216 6.76e-90 276.0 COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,1RRTP@1236|Gammaproteobacteria,464NN@72275|Alteromonadaceae 1236|Gammaproteobacteria T GGDEF domain - GO:0003674,GO:0003824,GO:0005488,GO:0008144,GO:0016740,GO:0016772,GO:0016779,GO:0019825,GO:0020037,GO:0036094,GO:0042165,GO:0043167,GO:0043169,GO:0046906,GO:0048037,GO:0052621,GO:0070025,GO:0097159,GO:1901363 2.7.7.65 ko:K13069 - - R08057 - ko00000,ko01000 - - - GGDEF k141_12017_2 1279017.AQYJ01000028_gene2029 8.93e-77 233.0 COG2110@1|root,COG2110@2|Bacteria,1NQ72@1224|Proteobacteria,1SPIK@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Macro domain - - - - - - - - - - - - Macro k141_15633_2 1280001.BAOA01000075_gene3184 3.05e-194 544.0 COG0861@1|root,COG0861@2|Bacteria,1MUNR@1224|Proteobacteria,1RP9Y@1236|Gammaproteobacteria,1XUEI@135623|Vibrionales 135623|Vibrionales P COG0861 Membrane protein TerC, possibly involved in tellurium resistance alx - - ko:K05794 - - - - ko00000 - - - TerC k141_15633_3 1280001.BAOA01000075_gene3183 2.26e-35 120.0 2AWQ5@1|root,31NM3@2|Bacteria,1QKBQ@1224|Proteobacteria,1TIF5@1236|Gammaproteobacteria,1XZ0U@135623|Vibrionales 135623|Vibrionales - - VPA0857 - - - - - - - - - - - - k141_15633_4 1116375.VEJY3_19991 3.14e-131 372.0 COG2824@1|root,COG2824@2|Bacteria,1RGUU@1224|Proteobacteria,1S60W@1236|Gammaproteobacteria,1XVM9@135623|Vibrionales 135623|Vibrionales P Zn-ribbon-containing protein involved in phosphonate metabolism phnA - - ko:K06193 ko01120,map01120 - - - ko00000 - - - PhnA,PhnA_Zn_Ribbon k141_28715_2 1453501.JELR01000001_gene1984 3.95e-46 154.0 COG2866@1|root,COG2866@2|Bacteria,1N9AY@1224|Proteobacteria,1RRGU@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Murein peptide amidase A mpaA GO:0000270,GO:0003674,GO:0003824,GO:0004040,GO:0004180,GO:0004181,GO:0005488,GO:0006022,GO:0006026,GO:0006027,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0009050,GO:0009056,GO:0009057,GO:0009253,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0019538,GO:0030203,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0046872,GO:0046914,GO:0061473,GO:0070011,GO:0071704,GO:0140096,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - ko:K14054 - - - - ko00000 - - iEC55989_1330.EC55989_1490,iECO103_1326.ECO103_1491 Peptidase_M14 k141_16778_1 1385515.N791_01965 8.32e-35 132.0 COG0577@1|root,COG0577@2|Bacteria,1MWBK@1224|Proteobacteria,1RPZF@1236|Gammaproteobacteria,1X3MX@135614|Xanthomonadales 135614|Xanthomonadales V ABC-type antimicrobial peptide transport system, permease component - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD k141_21581_1 1122951.ATUE01000005_gene1670 5.23e-196 549.0 COG4641@1|root,COG4641@2|Bacteria,1RD4C@1224|Proteobacteria,1RYDA@1236|Gammaproteobacteria,3NKBK@468|Moraxellaceae 1236|Gammaproteobacteria S Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_trans_1_2 k141_19137_1 1116375.VEJY3_13445 7.2e-196 547.0 COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,1RN0B@1236|Gammaproteobacteria,1XUSR@135623|Vibrionales 135623|Vibrionales NU COG5008 Tfp pilus assembly protein, ATPase PilU pilU - - ko:K02670 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE k141_19137_2 1280001.BAOA01000129_gene1251 3.52e-84 249.0 COG0816@1|root,COG0816@2|Bacteria,1RDHZ@1224|Proteobacteria,1S96Q@1236|Gammaproteobacteria,1XWVP@135623|Vibrionales 135623|Vibrionales L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA yqgF GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - ko:K07447 - - - - ko00000,ko01000 - - - RuvX k141_19137_3 1116375.VEJY3_13435 3.65e-131 372.0 COG1678@1|root,COG1678@2|Bacteria,1RCXM@1224|Proteobacteria,1S3YV@1236|Gammaproteobacteria,1XU0H@135623|Vibrionales 135623|Vibrionales K Belongs to the UPF0301 (AlgH) family yqgE - - ko:K07735 - - - - ko00000,ko03000 - - - DUF179 k141_19137_4 1219076.N646_1701 3.79e-222 613.0 COG0189@1|root,COG0189@2|Bacteria,1MVUA@1224|Proteobacteria,1RMU0@1236|Gammaproteobacteria,1XSEZ@135623|Vibrionales 135623|Vibrionales H Belongs to the prokaryotic GSH synthase family gshB GO:0003674,GO:0003824,GO:0004363,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0019184,GO:0034641,GO:0042398,GO:0043043,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044424,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901564,GO:1901566,GO:1901576 6.3.2.3 ko:K01920 ko00270,ko00480,ko01100,map00270,map00480,map01100 M00118 R00497,R10994 RC00096,RC00141 ko00000,ko00001,ko00002,ko01000 - - - GSH-S_ATP,GSH-S_N k141_19137_5 223926.28807620 2.9e-167 468.0 COG1385@1|root,COG1385@2|Bacteria,1MXCU@1224|Proteobacteria,1RPBN@1236|Gammaproteobacteria,1XUB1@135623|Vibrionales 135623|Vibrionales J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit rsmE - 2.1.1.193 ko:K09761 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_RNA k141_19137_6 1219076.N646_1699 5.88e-161 451.0 COG2356@1|root,COG2356@2|Bacteria,1MXQM@1224|Proteobacteria,1RPX9@1236|Gammaproteobacteria,1XSKD@135623|Vibrionales 135623|Vibrionales L COG2356 Endonuclease I endA GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0005575,GO:0005576,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 3.1.21.1 ko:K01150 - - - - ko00000,ko01000 - - - Endonuclease_1 k141_19137_7 1280001.BAOA01000129_gene1256 3.43e-98 287.0 COG3091@1|root,COG3091@2|Bacteria,1RJW4@1224|Proteobacteria,1S70F@1236|Gammaproteobacteria,1XW7P@135623|Vibrionales 135623|Vibrionales S Belongs to the SprT family sprT - - ko:K02742 - - - - ko00000 - - - SprT-like,Zn_ribbon_SprT k141_19137_8 1219076.N646_1696 2.21e-182 508.0 COG5473@1|root,COG5473@2|Bacteria,1MVRU@1224|Proteobacteria,1RPJA@1236|Gammaproteobacteria,1XSYE@135623|Vibrionales 135623|Vibrionales S Predicted integral membrane protein (DUF2189) - - - - - - - - - - - - DUF2189 k141_19137_9 223926.28807616 2.37e-271 743.0 COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,1RNV6@1236|Gammaproteobacteria,1XSPC@135623|Vibrionales 135623|Vibrionales H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme metK GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006556,GO:0006732,GO:0006790,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0044237,GO:0044249,GO:0044272,GO:0044424,GO:0044444,GO:0044464,GO:0046500,GO:0051186,GO:0051188,GO:0071704,GO:1901576 2.5.1.6 ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 M00034,M00035,M00368,M00609 R00177,R04771 RC00021,RC01211 ko00000,ko00001,ko00002,ko01000 - - - S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N k141_19137_10 1116375.VEJY3_13395 1.25e-247 692.0 COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,1RMWP@1236|Gammaproteobacteria,1XSX1@135623|Vibrionales 135623|Vibrionales G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate tkt - 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C,Transketolase_N k141_9633_1 223926.28805683 8.2e-131 374.0 COG0258@1|root,COG0258@2|Bacteria,1MX9Y@1224|Proteobacteria,1RQZE@1236|Gammaproteobacteria,1XTDZ@135623|Vibrionales 135623|Vibrionales L Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment xni GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006281,GO:0006308,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0033554,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575 - ko:K01146 - - - - ko00000 - - - 5_3_exonuc,5_3_exonuc_N k141_7303_3 218284.CCDN010000007_gene3995 7.3e-142 402.0 COG0356@1|root,COG0356@2|Bacteria,1TQIT@1239|Firmicutes,4H9NV@91061|Bacilli,1ZB02@1386|Bacillus 91061|Bacilli C it plays a direct role in the translocation of protons across the membrane atpB GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 - - ATP-synt_A k141_7303_4 1121091.AUMP01000005_gene1680 2.78e-33 115.0 COG0636@1|root,COG0636@2|Bacteria,1VEHP@1239|Firmicutes,4HNKQ@91061|Bacilli 91061|Bacilli C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpE GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_C k141_7303_5 218284.CCDN010000007_gene3997 4.22e-66 206.0 COG0711@1|root,COG0711@2|Bacteria,1VB85@1239|Firmicutes,4HM64@91061|Bacilli,1ZGHN@1386|Bacillus 91061|Bacilli C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) atpF - - ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - iYO844.BSU36850 ATP-synt_B k141_15658_1 1279017.AQYJ01000027_gene1803 9.27e-20 80.1 COG0230@1|root,COG0230@2|Bacteria,1NGGS@1224|Proteobacteria,1SGDJ@1236|Gammaproteobacteria,4690G@72275|Alteromonadaceae 1236|Gammaproteobacteria J Belongs to the bacterial ribosomal protein bL34 family rpmH GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02914 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L34 k141_26363_1 1078085.HMPREF1210_00509 2.26e-10 57.4 2DCFP@1|root,2ZDYD@2|Bacteria,1W69A@1239|Firmicutes,4I0W2@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - k141_26363_2 218284.CCDN010000001_gene1666 4.83e-108 315.0 COG2323@1|root,COG2323@2|Bacteria,1TX6U@1239|Firmicutes,4HEB2@91061|Bacilli,1ZQ03@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF421) - - - - - - - - - - - - DUF421 k141_35788_1 1131730.BAVI_16197 1.43e-29 115.0 COG0477@1|root,COG2814@2|Bacteria,1TSFM@1239|Firmicutes,4HABN@91061|Bacilli,1ZS92@1386|Bacillus 91061|Bacilli EGP COG0477 Permeases of the major facilitator superfamily yqjV - - - - - - - - - - - MFS_1,MFS_1_like,Sugar_tr k141_10821_1 218284.CCDN010000007_gene3873 4.67e-55 172.0 2CH76@1|root,3318K@2|Bacteria,1VGAH@1239|Firmicutes,4HP8U@91061|Bacilli,1ZI5T@1386|Bacillus 91061|Bacilli S Gas vesicle synthesis protein GvpO - - - - - - - - - - - - GvpO k141_18060_1 1042377.AFPJ01000008_gene2008 8.72e-113 340.0 COG0388@1|root,COG0388@2|Bacteria,1MXG5@1224|Proteobacteria 1224|Proteobacteria T Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - - - - - - - - - - CN_hydrolase k141_31110_1 1116375.VEJY3_06860 2.79e-159 447.0 COG0410@1|root,COG0410@2|Bacteria,1MU4Z@1224|Proteobacteria,1RMEM@1236|Gammaproteobacteria,1XUS7@135623|Vibrionales 135623|Vibrionales E Urea ABC transporter ATP-binding protein urtE - - ko:K11963 ko02010,map02010 M00323 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4.4,3.A.1.4.5 - - ABC_tran k141_31110_2 1116375.VEJY3_06855 4.48e-193 536.0 COG4674@1|root,COG4674@2|Bacteria,1MUBR@1224|Proteobacteria,1RM8F@1236|Gammaproteobacteria,1XVC5@135623|Vibrionales 135623|Vibrionales S Urea ABC transporter ATP-binding protein urtD - - ko:K11962 ko02010,map02010 M00323 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4.4,3.A.1.4.5 - - ABC_tran,BCA_ABC_TP_C k141_31110_3 1116375.VEJY3_06850 3.22e-246 677.0 COG4177@1|root,COG4177@2|Bacteria,1MUPI@1224|Proteobacteria,1RMAZ@1236|Gammaproteobacteria,1XTTH@135623|Vibrionales 135623|Vibrionales E Belongs to the binding-protein-dependent transport system permease family urtC - - ko:K11961 ko02010,map02010 M00323 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4.4,3.A.1.4.5 - - BPD_transp_2 k141_7336_1 648996.Theam_1567 5.2e-62 214.0 COG0458@1|root,COG0458@2|Bacteria,2G3RR@200783|Aquificae 200783|Aquificae F PFAM Carbamoyl-phosphate synthase L chain carB2 GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS k141_23936_1 218284.CCDN010000001_gene1434 3.05e-46 156.0 2CC31@1|root,2Z920@2|Bacteria,1UZSZ@1239|Firmicutes,4HCVB@91061|Bacilli,1ZGJ7@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_3797_2 1042377.AFPJ01000043_gene830 1.64e-23 98.2 COG0560@1|root,COG0560@2|Bacteria,1MWA3@1224|Proteobacteria,1RNJE@1236|Gammaproteobacteria,4647E@72275|Alteromonadaceae 1236|Gammaproteobacteria E phosphoserine phosphatase serB GO:0000287,GO:0001505,GO:0003674,GO:0003824,GO:0004647,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006563,GO:0006564,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0017144,GO:0019752,GO:0042133,GO:0042136,GO:0042578,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046872,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.3 ko:K01079 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R00582 RC00017 ko00000,ko00001,ko00002,ko01000,ko01009 - - iE2348C_1286.E2348C_4686,iEC042_1314.EC042_4885,iECO26_1355.ECO26_5594,iECSF_1327.ECSF_4321,iECUMN_1333.ECUMN_5012,iETEC_1333.ETEC_4743,iPC815.YPO0442,iUMNK88_1353.UMNK88_5307 ACT_6,HAD,Hydrolase k141_270_1 1453501.JELR01000001_gene2928 4.38e-20 84.7 COG0494@1|root,COG0494@2|Bacteria,1RD2C@1224|Proteobacteria,1SA4Q@1236|Gammaproteobacteria,467P1@72275|Alteromonadaceae 1236|Gammaproteobacteria L NUDIX domain - - - - - - - - - - - - NUDIX k141_31129_1 1385511.N783_00350 1.88e-119 348.0 COG2084@1|root,COG2084@2|Bacteria,1TR4F@1239|Firmicutes,4H9MA@91061|Bacilli,2Y9Z6@289201|Pontibacillus 91061|Bacilli I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase glxR - 1.1.1.31 ko:K00020 ko00280,ko01100,map00280,map01100 - R05066 RC00099 ko00000,ko00001,ko01000 - - - NAD_binding_11,NAD_binding_2 k141_31129_2 641107.CDLVIII_4036 2.39e-29 110.0 COG1514@1|root,COG1514@2|Bacteria,1VBG1@1239|Firmicutes,24IF5@186801|Clostridia,36J8F@31979|Clostridiaceae 186801|Clostridia J 2'-5' RNA ligase superfamily - - - - - - - - - - - - 2_5_RNA_ligase2 k141_18084_1 1385511.N783_14685 2.46e-63 205.0 COG2199@1|root,COG2199@2|Bacteria,1V5DB@1239|Firmicutes,4HI16@91061|Bacilli,2YAAV@289201|Pontibacillus 91061|Bacilli T Histidine kinase - - - - - - - - - - - - GGDEF,PAS_3 k141_36998_1 1294265.JCM21738_1735 7.24e-125 357.0 2DZYA@1|root,32RCQ@2|Bacteria,1UHMG@1239|Firmicutes,4IS3Y@91061|Bacilli,1ZS0Y@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_14474_1 1231057.AMGD01000081_gene886 3.55e-10 60.1 COG0604@1|root,COG0604@2|Bacteria,1TPGA@1239|Firmicutes,4HBKZ@91061|Bacilli,26EG4@186818|Planococcaceae 91061|Bacilli C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - 1.6.5.5 ko:K00344 - - - - ko00000,ko01000 - - - ADH_N,ADH_zinc_N k141_14474_2 218284.CCDN010000002_gene2407 3.64e-48 160.0 COG4912@1|root,COG4912@2|Bacteria,1TSAW@1239|Firmicutes,4HABR@91061|Bacilli,1ZBJS@1386|Bacillus 91061|Bacilli L DNA alkylation repair - - - - - - - - - - - - DNA_alkylation k141_35807_3 1279017.AQYJ01000028_gene2327 3.05e-81 247.0 COG3839@1|root,COG3839@2|Bacteria,1QXG5@1224|Proteobacteria,1T3B9@1236|Gammaproteobacteria,46AQA@72275|Alteromonadaceae 1236|Gammaproteobacteria G ATPases associated with a variety of cellular activities - - - - - - - - - - - - ABC_tran k141_35807_4 1279019.ARQK01000026_gene2469 4.34e-71 223.0 COG0390@1|root,COG0390@2|Bacteria,1MV2N@1224|Proteobacteria,1RSGA@1236|Gammaproteobacteria,1WW8S@135613|Chromatiales 135613|Chromatiales S PFAM conserved - - - ko:K02069 - M00211 - - ko00000,ko00002,ko02000 9.B.25.1 - - UPF0014 k141_1335_1 1453501.JELR01000002_gene952 0.0 1095.0 COG0643@1|root,COG0745@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,4650G@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0643 Chemotaxis protein histidine kinase and related kinases chpA - - ko:K02487,ko:K06596 ko02020,ko02025,map02020,map02025 M00507 - - ko00000,ko00001,ko00002,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg k141_31130_1 42565.FP66_10735 1.89e-40 140.0 COG1434@1|root,COG1434@2|Bacteria,1MVW8@1224|Proteobacteria,1S92A@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Conserved Protein - - - - - - - - - - - - DUF218 k141_31130_2 42565.FP66_10730 1.36e-39 135.0 COG0177@1|root,COG0177@2|Bacteria,1MUYQ@1224|Proteobacteria,1RMHU@1236|Gammaproteobacteria,1XHQJ@135619|Oceanospirillales 135619|Oceanospirillales L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate nth - 4.2.99.18 ko:K10773 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD k141_21624_1 1294265.JCM21738_953 2.53e-121 354.0 COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,4HB31@91061|Bacilli,1ZARE@1386|Bacillus 91061|Bacilli EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia trpE GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.1.3.27 ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Anth_synt_I_N,Chorismate_bind k141_13292_1 545264.KB898744_gene1961 3.82e-50 177.0 COG2170@1|root,COG2170@2|Bacteria,1MXET@1224|Proteobacteria,1RPKZ@1236|Gammaproteobacteria,1WWXK@135613|Chromatiales 135613|Chromatiales S glutamate--cysteine ligase - - - - - - - - - - - - GCS2 k141_13292_2 870187.Thini_1901 5.39e-80 254.0 COG3608@1|root,COG3608@2|Bacteria,1R784@1224|Proteobacteria,1RRY6@1236|Gammaproteobacteria 1236|Gammaproteobacteria S PFAM Succinylglutamate desuccinylase Aspartoacylase - - - - - - - - - - - - AstE_AspA k141_13292_3 1453501.JELR01000001_gene2743 5.85e-296 811.0 COG1611@1|root,COG1611@2|Bacteria,1MVQJ@1224|Proteobacteria,1RQHX@1236|Gammaproteobacteria,46503@72275|Alteromonadaceae 1236|Gammaproteobacteria S Rossmann fold nucleotide-binding protein ygdH GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016787,GO:0016798,GO:0016799,GO:0044424,GO:0044444,GO:0044464,GO:0047405 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - DUF3412,DUF4478,Lysine_decarbox k141_12087_1 1294265.JCM21738_1701 1.35e-140 401.0 COG1131@1|root,COG1131@2|Bacteria,1TPQW@1239|Firmicutes,4HA3P@91061|Bacilli,1ZCNQ@1386|Bacillus 91061|Bacilli V ABC transporter, ATP-binding protein potA5 - - ko:K01990,ko:K16921 ko02010,map02010 M00254,M00584 - - ko00000,ko00001,ko00002,ko02000 3.A.1 - - ABC_tran k141_26391_1 218284.CCDN010000002_gene2893 2.61e-39 137.0 COG0861@1|root,COG0861@2|Bacteria,1UYA9@1239|Firmicutes,4HETB@91061|Bacilli,1ZRX5@1386|Bacillus 91061|Bacilli P Integral membrane protein TerC family yjbE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - TerC k141_26391_2 871968.DESME_04970 2.85e-11 62.4 COG2323@1|root,COG2323@2|Bacteria,1V1AI@1239|Firmicutes,24EAT@186801|Clostridia 186801|Clostridia S Protein of unknown function (DUF421) - - - - - - - - - - - - DUF421 k141_25135_1 1232683.ADIMK_1954 5.3e-19 92.8 COG3170@1|root,COG3170@2|Bacteria,1MXV7@1224|Proteobacteria,1RMM5@1236|Gammaproteobacteria,4646P@72275|Alteromonadaceae 1236|Gammaproteobacteria NU COG3170 Tfp pilus assembly protein FimV fimV - - ko:K08086 - - - - ko00000 - - - LysM,TPR_19 k141_3798_1 1453501.JELR01000002_gene579 1.77e-124 387.0 COG0642@1|root,COG0784@1|root,COG1457@1|root,COG0784@2|Bacteria,COG1457@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1RRGT@1236|Gammaproteobacteria,464VX@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0642 Signal transduction histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,Response_reg k141_1336_1 218284.CCDN010000005_gene3474 1.4e-116 345.0 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4HB97@91061|Bacilli,1ZBGZ@1386|Bacillus 91061|Bacilli C Belongs to the aldehyde dehydrogenase family ywdH - 1.2.1.3 ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_272_1 1294265.JCM21738_2689 6.57e-112 330.0 COG0367@1|root,COG0367@2|Bacteria,1TRPB@1239|Firmicutes,4HA44@91061|Bacilli,1ZBY8@1386|Bacillus 91061|Bacilli E Asparagine synthase asnO - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 k141_6216_1 1123236.KB899387_gene1953 2.29e-126 387.0 COG4772@1|root,COG4772@2|Bacteria,1MUIH@1224|Proteobacteria,1RQYX@1236|Gammaproteobacteria,46D6R@72275|Alteromonadaceae 1236|Gammaproteobacteria P TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_6216_2 717774.Marme_3847 8.98e-87 266.0 COG0398@1|root,COG0398@2|Bacteria,1RBAE@1224|Proteobacteria,1S32X@1236|Gammaproteobacteria,1XJ8I@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function, DUF547 - - - - - - - - - - - - DUF547 k141_6216_3 1122194.AUHU01000015_gene2971 0.0 934.0 COG4773@1|root,COG4773@2|Bacteria,1NXPR@1224|Proteobacteria,1RSBC@1236|Gammaproteobacteria,4657C@72275|Alteromonadaceae 1236|Gammaproteobacteria P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec k141_27505_1 666686.B1NLA3E_03750 1.25e-204 583.0 COG0370@1|root,COG0370@2|Bacteria,1TP7E@1239|Firmicutes,4HBCS@91061|Bacilli,1ZCZU@1386|Bacillus 91061|Bacilli P transporter of a GTP-driven Fe(2 ) uptake system feoB - - ko:K04759 - - - - ko00000,ko02000 9.A.8.1 - iSB619.SA_RS13395 FeoB_C,FeoB_N,Gate k141_4918_1 1279017.AQYJ01000029_gene3319 8.66e-70 218.0 29NNR@1|root,309KP@2|Bacteria,1R91H@1224|Proteobacteria,1S9MB@1236|Gammaproteobacteria,46BMA@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_4918_2 1101190.ARWB01000001_gene2386 3.23e-66 205.0 COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,2U6Z6@28211|Alphaproteobacteria,3705T@31993|Methylocystaceae 28211|Alphaproteobacteria C [2Fe-2S] binding domain iorA - 1.3.99.16 ko:K07302 - - - - ko00000,ko01000 - - - Fer2,Fer2_2 k141_4918_3 426117.M446_2576 3.18e-168 501.0 COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,2TQVK@28211|Alphaproteobacteria,1JT8T@119045|Methylobacteriaceae 28211|Alphaproteobacteria C aldehyde oxidase and xanthine dehydrogenase molybdopterin binding iorB - 1.3.99.16 ko:K07303 - - - - ko00000,ko01000 - - - Ald_Xan_dh_C2 k141_22768_1 1340434.AXVA01000003_gene1930 2.3e-156 464.0 COG0249@1|root,COG0249@2|Bacteria,1TPRJ@1239|Firmicutes,4HA63@91061|Bacilli,1ZB93@1386|Bacillus 91061|Bacilli L that it carries out the mismatch recognition step. This protein has a weak ATPase activity mutS GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K03555 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V k141_3799_1 1453501.JELR01000002_gene591 1.75e-113 329.0 COG3047@1|root,COG3047@2|Bacteria,1NUZJ@1224|Proteobacteria,1RRRC@1236|Gammaproteobacteria,467CK@72275|Alteromonadaceae 1236|Gammaproteobacteria M Outer membrane protein W ompW - - ko:K07275 - - - - ko00000 - - - OmpW k141_1337_1 1042377.AFPJ01000032_gene2709 4e-77 238.0 COG2264@1|root,COG2264@2|Bacteria,1MUPC@1224|Proteobacteria,1RNAR@1236|Gammaproteobacteria,4650B@72275|Alteromonadaceae 1236|Gammaproteobacteria J Ribosomal protein L11 methyltransferase prmA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006480,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0018011,GO:0018012,GO:0018022,GO:0018023,GO:0018193,GO:0018194,GO:0018205,GO:0019538,GO:0031365,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 - ko:K02687 - - - - ko00000,ko01000,ko03009 - - - PrmA k141_16818_2 935837.JAEK01000024_gene1020 4.16e-96 281.0 COG0049@1|root,COG0049@2|Bacteria,1V1GG@1239|Firmicutes,4H9PA@91061|Bacilli,1ZBVR@1386|Bacillus 91061|Bacilli J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA rpsG GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02992 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S7 k141_27506_1 1444310.JANV01000087_gene397 2.49e-80 258.0 COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,4HB12@91061|Bacilli,1ZCM9@1386|Bacillus 91061|Bacilli L ATP-dependent DNA helicase pcrA - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C k141_27506_2 1385513.N780_17920 6.52e-06 47.0 COG1646@1|root,COG1646@2|Bacteria,1TQQK@1239|Firmicutes,4H9YW@91061|Bacilli,2Y9NW@289201|Pontibacillus 91061|Bacilli I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales pcrB GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 - ko:K07094 - - - - ko00000,ko01000 - - - PcrB k141_10846_2 796606.BMMGA3_00825 5.17e-72 217.0 COG0099@1|root,COG0099@2|Bacteria,1V3JH@1239|Firmicutes,4HGX6@91061|Bacilli,1ZGAW@1386|Bacillus 91061|Bacilli J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits rpsM GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02952 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S13 k141_10846_3 997296.PB1_06517 1.28e-78 234.0 COG0100@1|root,COG0100@2|Bacteria,1V3IK@1239|Firmicutes,4HH2T@91061|Bacilli,1ZFIU@1386|Bacillus 91061|Bacilli J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome rpsK GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02948 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S11 k141_10846_4 1274524.BSONL12_22129 6.11e-77 237.0 COG0202@1|root,COG0202@2|Bacteria,1TPR8@1239|Firmicutes,4H9R1@91061|Bacilli,1ZBHX@1386|Bacillus 91061|Bacilli K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoA GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L k141_2596_1 1042377.AFPJ01000004_gene339 2.14e-159 468.0 COG1175@1|root,COG2182@1|root,COG1175@2|Bacteria,COG2182@2|Bacteria,1MXKR@1224|Proteobacteria,1RN6B@1236|Gammaproteobacteria,46801@72275|Alteromonadaceae 1236|Gammaproteobacteria G COG1175 ABC-type sugar transport systems, permease components malF GO:0003674,GO:0003824,GO:0005215,GO:0005363,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006950,GO:0006974,GO:0008150,GO:0008643,GO:0009987,GO:0015144,GO:0015154,GO:0015157,GO:0015399,GO:0015405,GO:0015422,GO:0015423,GO:0015766,GO:0015768,GO:0015772,GO:0015774,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0033037,GO:0033554,GO:0034219,GO:0042623,GO:0042626,GO:0042956,GO:0043190,GO:0043211,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990060,GO:1990351 - ko:K10109,ko:K15771 ko02010,map02010 M00194,M00491 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.1,3.A.1.1.16,3.A.1.1.2,3.A.1.1.22 - iZ_1308.Z5631 BPD_transp_1,MalF_P2 k141_2596_2 1042377.AFPJ01000004_gene340 7.8e-20 88.2 COG3833@1|root,COG3833@2|Bacteria,1R28D@1224|Proteobacteria,1T5IQ@1236|Gammaproteobacteria,46DBX@72275|Alteromonadaceae 1236|Gammaproteobacteria G Binding-protein-dependent transport system inner membrane component - - - ko:K15772 ko02010,map02010 M00491 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.16,3.A.1.1.2 - - BPD_transp_1 k141_3800_1 1294265.JCM21738_2670 3.08e-87 283.0 COG3857@1|root,COG3857@2|Bacteria,1TQJW@1239|Firmicutes,4HAY6@91061|Bacilli,1ZC70@1386|Bacillus 91061|Bacilli L ATP-dependent helicase deoxyribonuclease subunit B rexB GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0004527,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.6.4.12 ko:K16899 - - - - ko00000,ko01000,ko03400 - - - Exonuc_V_gamma,PDDEXK_1,UvrD_C k141_3800_2 1340434.AXVA01000002_gene1268 1.03e-18 84.7 COG1074@1|root,COG1074@2|Bacteria,1TQ35@1239|Firmicutes,4HA64@91061|Bacilli,1ZBG6@1386|Bacillus 91061|Bacilli L ATP-dependent helicase nuclease subunit A addA GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 3.6.4.12 ko:K16898 - - - - ko00000,ko01000,ko03400 - - - PDDEXK_1,UvrD-helicase,UvrD_C k141_18086_1 1279017.AQYJ01000023_gene3194 2.7e-75 229.0 COG1714@1|root,COG1714@2|Bacteria,1N7R6@1224|Proteobacteria,1SCCT@1236|Gammaproteobacteria,468CD@72275|Alteromonadaceae 1236|Gammaproteobacteria S membrane protein domain - - - - - - - - - - - - RDD k141_29872_1 218284.CCDN010000001_gene17 2.79e-75 228.0 COG0806@1|root,COG0806@2|Bacteria,1V6HD@1239|Firmicutes,4HH3H@91061|Bacilli,1ZFP2@1386|Bacillus 91061|Bacilli J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes rimM - - ko:K02860 - - - - ko00000,ko03009 - - - PRC,RimM k141_29872_2 218284.CCDN010000001_gene18 2.09e-63 196.0 2BIN4@1|root,32CV6@2|Bacteria,1VC14@1239|Firmicutes,4HJYF@91061|Bacilli,1ZGYX@1386|Bacillus 91061|Bacilli S YlqD protein - - - - - - - - - - - - YlqD k141_36999_1 218284.CCDN010000004_gene3088 1.3e-147 430.0 COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,4HA1G@91061|Bacilli,1ZASC@1386|Bacillus 91061|Bacilli G COG0366 Glycosidases malL GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.2.1.10 ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00801,R01718,R01791,R06199 RC00028,RC00059,RC00077,RC00451 ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,Malt_amylase_C k141_25139_1 866895.HBHAL_1495 1.21e-67 216.0 COG0644@1|root,COG0644@2|Bacteria,1TQRM@1239|Firmicutes,4HEZX@91061|Bacilli 91061|Bacilli C NAD(P)-binding Rossmann-like domain - - - - - - - - - - - - NAD_binding_8 k141_14476_1 1042377.AFPJ01000051_gene110 2.84e-08 53.9 COG0598@1|root,COG0598@2|Bacteria,1MWMP@1224|Proteobacteria,1RNDQ@1236|Gammaproteobacteria,465JG@72275|Alteromonadaceae 1236|Gammaproteobacteria P Mediates influx of magnesium ions corA GO:0000041,GO:0003674,GO:0005215,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0008150,GO:0008324,GO:0015075,GO:0015087,GO:0015095,GO:0015099,GO:0015318,GO:0015675,GO:0015693,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0035444,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:1903830 - ko:K03284 - - - - ko00000,ko02000 1.A.35.1,1.A.35.3 - iYL1228.KPN_04313 CorA k141_26395_1 218284.CCDN010000001_gene1387 4.22e-88 278.0 COG2905@1|root,COG2905@2|Bacteria,1TQFI@1239|Firmicutes,4HDTM@91061|Bacilli,1ZQQC@1386|Bacillus 91061|Bacilli T Putative nucleotidyltransferase substrate binding domain - - - ko:K07182 - - - - ko00000 - - - CBS,DUF294,DUF294_C,cNMP_binding k141_1339_1 1122137.AQXF01000001_gene2679 1.82e-53 189.0 COG1629@1|root,COG4771@2|Bacteria,1MUNK@1224|Proteobacteria,2TRCG@28211|Alphaproteobacteria 28211|Alphaproteobacteria P receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_31131_1 313603.FB2170_12956 1.88e-87 283.0 COG1228@1|root,COG1228@2|Bacteria,4NEV0@976|Bacteroidetes,1HZW4@117743|Flavobacteriia,2PHHE@252356|Maribacter 976|Bacteroidetes Q Amidohydrolase family - - - - - - - - - - - - Amidohydro_1 k141_10847_1 557598.LHK_02508 1.12e-37 141.0 COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,2VJ9R@28216|Betaproteobacteria,2KPTT@206351|Neisseriales 206351|Neisseriales P Psort location CytoplasmicMembrane, score 10.00 - - - ko:K14445 - - - - ko00000,ko02000 2.A.47.1 - - Na_sulph_symp k141_274_1 1453501.JELR01000002_gene418 4.45e-102 296.0 COG0782@1|root,COG0782@2|Bacteria,1RCXW@1224|Proteobacteria,1S3UP@1236|Gammaproteobacteria,466V2@72275|Alteromonadaceae 1236|Gammaproteobacteria K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides greA GO:0001098,GO:0001108,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006354,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0032784,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - ko:K03624 - - - - ko00000,ko03021 - - - GreA_GreB,GreA_GreB_N k141_12090_2 1294265.JCM21738_1275 1.91e-99 296.0 COG0583@1|root,COG0583@2|Bacteria 2|Bacteria K DNA-binding transcription factor activity - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - HTH_1,LysR_substrate,NMT1_2 k141_2597_1 218284.CCDN010000001_gene632 6.61e-35 130.0 COG1530@1|root,COG1530@2|Bacteria,1TQS4@1239|Firmicutes,4HC3Q@91061|Bacilli,1ZCCF@1386|Bacillus 91061|Bacilli J ribonuclease, Rne Rng family rng - - ko:K08301 - - - - ko00000,ko01000,ko03009,ko03019 - - - RNase_E_G,S1 k141_2597_2 218284.CCDN010000001_gene633 6.6e-66 200.0 COG0261@1|root,COG0261@2|Bacteria,1V9YH@1239|Firmicutes,4HIGK@91061|Bacilli,1ZGZG@1386|Bacillus 91061|Bacilli J This protein binds to 23S rRNA in the presence of protein L20 rplU GO:0003674,GO:0003735,GO:0005198 - ko:K02888 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L21p k141_21626_1 218284.CCDN010000002_gene2156 2.18e-159 478.0 COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,4HAFP@91061|Bacilli,1ZBJ3@1386|Bacillus 91061|Bacilli V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family swrC - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran k141_26396_1 1294265.JCM21738_1352 8.3e-34 125.0 COG0260@1|root,COG0260@2|Bacteria,1TPJZ@1239|Firmicutes,4HAPW@91061|Bacilli,1ZBZU@1386|Bacillus 91061|Bacilli E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides pepA - 3.4.11.1 ko:K01255 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - Peptidase_M17,Peptidase_M17_N k141_26396_2 1294265.JCM21738_1353 1.24e-44 146.0 COG1547@1|root,COG1547@2|Bacteria,1V9RH@1239|Firmicutes,4HJA4@91061|Bacilli,1ZGEY@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF309) - - - ko:K09763 - - - - ko00000 - - - DUF309 k141_35809_1 1280001.BAOA01000078_gene3161 4.44e-75 232.0 COG4168@1|root,COG4168@2|Bacteria,1QUAU@1224|Proteobacteria,1T1RR@1236|Gammaproteobacteria,1XTN1@135623|Vibrionales 135623|Vibrionales P peptide transport system, permease sapB - - ko:K19227 ko01503,ko02010,map01503,map02010 M00739 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.5 - - BPD_transp_1 k141_25141_2 218284.CCDN010000001_gene1435 3.91e-75 227.0 2B66C@1|root,2ZBXK@2|Bacteria,1V1NZ@1239|Firmicutes,4IREM@91061|Bacilli,1ZRTU@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_7338_1 1116375.VEJY3_06380 1.14e-131 374.0 2EYK5@1|root,33RTU@2|Bacteria,1NQK6@1224|Proteobacteria,1SJR2@1236|Gammaproteobacteria,1Y29P@135623|Vibrionales 135623|Vibrionales S Phosphoribosyl-ATP pyrophosphohydrolase - - - - - - - - - - - - PRA-PH k141_7338_2 1116375.VEJY3_06375 5.48e-159 448.0 COG4138@1|root,COG4138@2|Bacteria,1NXS9@1224|Proteobacteria,1RRMD@1236|Gammaproteobacteria,1XTPP@135623|Vibrionales 135623|Vibrionales P Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system btuD GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006855,GO:0008150,GO:0015238,GO:0015399,GO:0015405,GO:0015420,GO:0015889,GO:0015893,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0035461,GO:0042221,GO:0042493,GO:0042623,GO:0042626,GO:0043492,GO:0050896,GO:0051179,GO:0051180,GO:0051181,GO:0051184,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0090482 3.6.3.33 ko:K06074 ko02010,map02010 M00241 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.13 - - ABC_tran k141_7338_3 223926.28806299 2.21e-214 597.0 COG4139@1|root,COG4139@2|Bacteria,1R34H@1224|Proteobacteria,1RR7W@1236|Gammaproteobacteria,1XUHT@135623|Vibrionales 135623|Vibrionales H Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane btuC GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006855,GO:0008150,GO:0015238,GO:0015399,GO:0015405,GO:0015420,GO:0015889,GO:0015893,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0035461,GO:0042221,GO:0042493,GO:0042623,GO:0042626,GO:0043492,GO:0050896,GO:0051179,GO:0051180,GO:0051181,GO:0051184,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0090482 - ko:K06073 ko02010,map02010 M00241 - - ko00000,ko00001,ko00002,ko02000 3.A.1.13 - - FecCD k141_10848_1 556268.OFAG_00399 6.98e-12 63.9 2E7BZ@1|root,331V9@2|Bacteria,1N8MZ@1224|Proteobacteria,2W3YC@28216|Betaproteobacteria 28216|Betaproteobacteria S Domain of Unknown Function (DUF1540) - - - - - - - - - - - - DUF1540 k141_32229_2 1042377.AFPJ01000019_gene2484 3.19e-22 95.9 COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,1RMBY@1236|Gammaproteobacteria,46A44@72275|Alteromonadaceae 1236|Gammaproteobacteria V COG0577 ABC-type antimicrobial peptide transport system, permease component - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD k141_26460_2 441769.ABFU01000018_gene3631 5.65e-116 337.0 COG0765@1|root,COG0765@2|Bacteria,1TPQ8@1239|Firmicutes,4H9N1@91061|Bacilli,1ZBG5@1386|Bacillus 91061|Bacilli P COG0765 ABC-type amino acid transport system, permease component tcyB GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015318,GO:0015711,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1903825,GO:1905039 - ko:K10009 ko02010,map02010 M00234 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.10,3.A.1.3.14 - iYO844.BSU03600 BPD_transp_1 k141_26460_3 218284.CCDN010000004_gene3138 5.62e-117 340.0 COG0834@1|root,COG0834@2|Bacteria,1TR13@1239|Firmicutes,4HBRP@91061|Bacilli,1ZCH3@1386|Bacillus 91061|Bacilli ET Belongs to the bacterial solute-binding protein 3 family tcyA - - ko:K02424 ko02010,map02010 M00234 - - ko00000,ko00001,ko00002,ko02000,ko02035 3.A.1.3.10,3.A.1.3.14 - - SBP_bac_3 k141_6298_2 1453501.JELR01000001_gene1951 2.29e-48 154.0 COG0228@1|root,COG0228@2|Bacteria,1MZCT@1224|Proteobacteria,1S8RT@1236|Gammaproteobacteria,467U2@72275|Alteromonadaceae 1236|Gammaproteobacteria J Belongs to the bacterial ribosomal protein bS16 family rpsP GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02959 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S16 k141_6298_3 1042377.AFPJ01000037_gene2889 1.47e-22 91.3 COG0806@1|root,COG0806@2|Bacteria,1MWQR@1224|Proteobacteria,1RNJ2@1236|Gammaproteobacteria,467CY@72275|Alteromonadaceae 1236|Gammaproteobacteria J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes rimM GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 - ko:K02860 - - - - ko00000,ko03009 - - - PRC,RimM k141_10898_2 414684.RC1_4072 2.73e-69 224.0 COG1091@1|root,COG1091@2|Bacteria,1MUXM@1224|Proteobacteria,2TSP6@28211|Alphaproteobacteria,2JPW5@204441|Rhodospirillales 204441|Rhodospirillales M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose rfbD - 1.1.1.133 ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777 RC00182 ko00000,ko00001,ko00002,ko01000 - - - RmlD_sub_bind k141_10898_3 1218075.BAYA01000006_gene2286 5.79e-65 204.0 COG1898@1|root,COG1898@2|Bacteria,1R9YD@1224|Proteobacteria,2VQ02@28216|Betaproteobacteria,1K0BA@119060|Burkholderiaceae 28216|Betaproteobacteria M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose rfbC - 5.1.3.13 ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R06514 RC01531 ko00000,ko00001,ko00002,ko01000 - - - dTDP_sugar_isom k141_10898_4 1192124.LIG30_2217 4.22e-150 429.0 COG1209@1|root,COG1209@2|Bacteria,1MU0X@1224|Proteobacteria,2VHA6@28216|Betaproteobacteria,1JZPM@119060|Burkholderiaceae 28216|Betaproteobacteria H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis rfbA - 2.7.7.24 ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 M00793 R02328 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase k141_10898_5 1111728.ATYS01000050_gene3552 4.18e-169 482.0 COG1088@1|root,COG1088@2|Bacteria,1MU5E@1224|Proteobacteria,1RP7G@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily rffG GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008460,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0045226,GO:0046379,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 4.2.1.46 ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 M00793 R06513 RC00402 ko00000,ko00001,ko00002,ko01000 - - iECNA114_1301.ECNA114_3926,iECSF_1327.ECSF_3628 GDP_Man_Dehyd k141_15710_1 672.VV93_v1c17500 4.27e-114 337.0 COG3203@1|root,COG3203@2|Bacteria,1Q1XX@1224|Proteobacteria,1RPIH@1236|Gammaproteobacteria,1XXTE@135623|Vibrionales 135623|Vibrionales M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - - - - - - - - - - - k141_15710_2 672.VV93_v1c17510 8.61e-69 210.0 COG0226@1|root,COG0226@2|Bacteria,1N7RX@1224|Proteobacteria,1SCQW@1236|Gammaproteobacteria,1XZ44@135623|Vibrionales 135623|Vibrionales P ABC-type phosphate transport system, periplasmic component - - - - - - - - - - - - - k141_15710_3 1116375.VEJY3_00310 4.03e-67 204.0 291H9@1|root,2ZP3V@2|Bacteria,1RDHD@1224|Proteobacteria,1S3P8@1236|Gammaproteobacteria,1XXMB@135623|Vibrionales 135623|Vibrionales S Universal stress protein B homolog uspB - - ko:K06144 - - - - ko00000,ko02000 9.B.4.1.1 - - UspB k141_15710_4 1219077.VAZ01S_065_00150 1.51e-115 332.0 COG1528@1|root,COG1528@2|Bacteria,1R9ZC@1224|Proteobacteria,1RYVB@1236|Gammaproteobacteria,1XTQA@135623|Vibrionales 135623|Vibrionales P Iron-storage protein ftnA - 1.16.3.2 ko:K02217 - - - - ko00000,ko01000 - - - Ferritin k141_15710_5 1116375.VEJY3_00300 2.92e-92 270.0 COG0589@1|root,COG0589@2|Bacteria,1MV6Y@1224|Proteobacteria,1RQQ7@1236|Gammaproteobacteria,1XWVC@135623|Vibrionales 135623|Vibrionales T COG0589 Universal stress protein UspA and related nucleotide-binding proteins uspA - - ko:K06149 - - - - ko00000 - - - Usp k141_15710_6 1116375.VEJY3_00295 1.06e-200 556.0 COG0697@1|root,COG0697@2|Bacteria,1MWMC@1224|Proteobacteria,1RQST@1236|Gammaproteobacteria,1XTFF@135623|Vibrionales 135623|Vibrionales EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily yigM - - - - - - - - - - - EamA k141_15710_7 1116375.VEJY3_00290 9.85e-78 237.0 2ES0Z@1|root,33JK1@2|Bacteria,1NHKR@1224|Proteobacteria,1SI94@1236|Gammaproteobacteria,1XY8R@135623|Vibrionales 135623|Vibrionales - - VC0074 - - - - - - - - - - - - k141_15710_8 1116375.VEJY3_00285 3.51e-176 492.0 COG0742@1|root,COG0742@2|Bacteria,1MX8Z@1224|Proteobacteria,1RMIB@1236|Gammaproteobacteria,1XTAA@135623|Vibrionales 135623|Vibrionales J Specifically methylates the guanosine in position 1516 of 16S rRNA rsmJ - 2.1.1.242 ko:K15984 - - - - ko00000,ko01000,ko03009 - - - SAM_MT k141_15710_10 1116375.VEJY3_00275 2.78e-78 250.0 COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,1RMAH@1236|Gammaproteobacteria,1XTEV@135623|Vibrionales 135623|Vibrionales E COG0339 Zn-dependent oligopeptidases prlC - 3.4.24.70 ko:K01414 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M3 k141_19225_1 1384054.N790_08735 1.97e-63 212.0 COG2234@1|root,COG2234@2|Bacteria,1NE83@1224|Proteobacteria,1RN9P@1236|Gammaproteobacteria,1X3HG@135614|Xanthomonadales 135614|Xanthomonadales S aminopeptidase - - - - - - - - - - - - Peptidase_M28 k141_9702_1 315750.BPUM_1042 4.14e-50 170.0 COG0002@1|root,COG0002@2|Bacteria,1TPVI@1239|Firmicutes,4H9YD@91061|Bacilli,1ZBHP@1386|Bacillus 91061|Bacilli E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde argC GO:0003674,GO:0003824,GO:0003942,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.38 ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R03443 RC00684 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU11190 Semialdhyde_dh,Semialdhyde_dhC k141_35858_1 218284.CCDN010000004_gene3056 2.77e-63 197.0 2DKHE@1|root,309GB@2|Bacteria,1U50R@1239|Firmicutes,4IESM@91061|Bacilli,1ZI04@1386|Bacillus 91061|Bacilli S Intracellular proteinase inhibitor - - - - - - - - - - - - BsuPI k141_22805_1 218284.CCDN010000001_gene1911 5.31e-109 327.0 COG1419@1|root,COG1419@2|Bacteria,1TSP7@1239|Firmicutes,4H9VG@91061|Bacilli,1ZCJ9@1386|Bacillus 91061|Bacilli N Flagellar biosynthesis regulator FlhF flhF GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K02404 - - - - ko00000,ko02035 - - - SRP54 k141_37038_1 1263831.F543_19610 7.65e-07 55.1 COG1887@1|root,COG1887@2|Bacteria,1RA5A@1224|Proteobacteria,1TFQT@1236|Gammaproteobacteria,1Y9SF@135625|Pasteurellales 135625|Pasteurellales M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase - - - - - - - - - - - - Glyphos_transf k141_12170_1 1042377.AFPJ01000038_gene1110 2.71e-77 246.0 COG4942@1|root,COG4942@2|Bacteria,1MY3E@1224|Proteobacteria,1RPQP@1236|Gammaproteobacteria,465VU@72275|Alteromonadaceae 1236|Gammaproteobacteria D COG4942 Membrane-bound metallopeptidase envC GO:0000920,GO:0001896,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008219,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0012501,GO:0016020,GO:0016787,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0042546,GO:0042597,GO:0043085,GO:0044085,GO:0044093,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071554,GO:0071840,GO:0071944 - - - - - - - - - - Peptidase_M23 k141_12170_2 1279017.AQYJ01000027_gene1990 0.0 900.0 COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,1RMJE@1236|Gammaproteobacteria,465AD@72275|Alteromonadaceae 1236|Gammaproteobacteria G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate gpmI GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030145,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046537,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.4.2.12 ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000 - - iECSE_1348.ECSE_3895,iJN746.PP_5056 Metalloenzyme,Phosphodiest,iPGM_N k141_12170_7 1279017.AQYJ01000027_gene1995 2.99e-162 459.0 COG1028@1|root,COG1028@2|Bacteria,1MUSQ@1224|Proteobacteria,1RQQ9@1236|Gammaproteobacteria,469WQ@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) hsdl2 - - ko:K13775 ko00281,map00281 - R08087,R08096,R10125,R10126 RC00080,RC00087 ko00000,ko00001 - - - adh_short,adh_short_C2 k141_12170_11 1279017.AQYJ01000027_gene1999 1.55e-204 578.0 COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,1RMW3@1236|Gammaproteobacteria,463Y1@72275|Alteromonadaceae 1236|Gammaproteobacteria G Belongs to the pyruvate kinase family pykA GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016043,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - e_coli_core.b1854,iAF1260.b1854,iB21_1397.B21_01813,iBWG_1329.BWG_1668,iEC042_1314.EC042_2021,iECBD_1354.ECBD_1784,iECB_1328.ECB_01825,iECDH10B_1368.ECDH10B_1995,iECDH1ME8569_1439.ECDH1ME8569_1801,iECD_1391.ECD_01825,iECO103_1326.ECO103_2044,iECO111_1330.ECO111_2362,iECO26_1355.ECO26_2692,iECUMN_1333.ECUMN_2152,iETEC_1333.ETEC_1887,iEcDH1_1363.EcDH1_1786,iEcE24377_1341.EcE24377A_2084,iEcHS_1320.EcHS_A1947,iEcSMS35_1347.EcSMS35_1332,iEcolC_1368.EcolC_1778,iG2583_1286.G2583_2306,iJO1366.b1854,iJR904.b1854,iSBO_1134.SBO_1162,iSSON_1240.SSON_1294,iSbBS512_1146.SbBS512_E2130,iUMNK88_1353.UMNK88_2326,iY75_1357.Y75_RS09740 PK,PK_C k141_21664_1 1279017.AQYJ01000026_gene31 0.0 1067.0 COG4913@1|root,COG4913@2|Bacteria,1N16Z@1224|Proteobacteria,1RYVF@1236|Gammaproteobacteria,465ZJ@72275|Alteromonadaceae 1236|Gammaproteobacteria S Putative exonuclease SbcCD, C subunit - - - - - - - - - - - - AAA_29,SbcCD_C k141_3850_1 1131451.O1K_19071 1.52e-22 95.5 COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,1RMCV@1236|Gammaproteobacteria,1X4AH@135614|Xanthomonadales 135614|Xanthomonadales E cystathionine - - 4.4.1.1 ko:K01758 ko00260,ko00270,ko00450,ko01100,ko01130,ko01230,map00260,map00270,map00450,map01100,map01130,map01230 M00338 R00782,R01001,R02408,R04770,R04930,R09366 RC00056,RC00069,RC00348,RC00382,RC00710,RC01209,RC01210,RC01245,RC02303 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Cys_Met_Meta_PP k141_3850_2 1123399.AQVE01000016_gene2711 2.83e-83 256.0 COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,1RM7Q@1236|Gammaproteobacteria,4604F@72273|Thiotrichales 72273|Thiotrichales J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA prfA - - ko:K02835 - - - - ko00000,ko03012 - - - PCRF,RF-1 k141_18130_1 1279017.AQYJ01000023_gene3271 1.89e-10 58.2 COG5591@1|root,COG5591@2|Bacteria,1N7TH@1224|Proteobacteria,1SF7U@1236|Gammaproteobacteria,46BWG@72275|Alteromonadaceae 1236|Gammaproteobacteria S Peptidase propeptide and YPEB domain - - - - - - - - - - - - PepSY_2 k141_33493_1 1279017.AQYJ01000027_gene1725 3.99e-66 218.0 COG2234@1|root,COG2234@2|Bacteria,1MUZ7@1224|Proteobacteria,1RS0Q@1236|Gammaproteobacteria,4653N@72275|Alteromonadaceae 1236|Gammaproteobacteria S PA domain - - - - - - - - - - - - PA,Peptidase_M28 k141_33493_2 1121935.AQXX01000126_gene885 2.37e-108 335.0 COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,1RPU5@1236|Gammaproteobacteria,1XI9X@135619|Oceanospirillales 135619|Oceanospirillales P Sodium:sulfate symporter transmembrane region - - - ko:K14445 - - - - ko00000,ko02000 2.A.47.1 - - Na_sulph_symp k141_33493_3 1279017.AQYJ01000027_gene1726 5.77e-118 343.0 28Q1W@1|root,2ZCK4@2|Bacteria,1RE1D@1224|Proteobacteria,1T19A@1236|Gammaproteobacteria,46D1X@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_33493_4 911045.PSE_3823 5.84e-27 104.0 COG3602@1|root,COG3602@2|Bacteria,1MZKQ@1224|Proteobacteria,2U85U@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein conserved in bacteria - - - ko:K09964 - - - - ko00000 - - - ACT_3,ACT_7 k141_33493_7 1279017.AQYJ01000027_gene1732 1.66e-115 349.0 COG2010@1|root,COG2010@2|Bacteria,1R28S@1224|Proteobacteria,1T5JD@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Cytochrome c - - - - - - - - - - - - Cytochrome_CBB3 k141_33493_9 1279017.AQYJ01000027_gene1734 1.34e-108 318.0 COG2863@1|root,COG2863@2|Bacteria,1N2NB@1224|Proteobacteria,1RZFP@1236|Gammaproteobacteria,466NK@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG2863 Cytochrome c553 cc4 - - - - - - - - - - - Cytochrom_C,Cytochrome_CBB3 k141_19239_1 1348635.BBJY01000016_gene3965 8.14e-174 497.0 COG1129@1|root,COG1129@2|Bacteria,1MU22@1224|Proteobacteria,1RMCH@1236|Gammaproteobacteria,1XY8T@135623|Vibrionales 135623|Vibrionales G Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - 3.6.3.17 ko:K02056 - M00221 - - ko00000,ko00002,ko01000,ko02000 3.A.1.2 - - ABC_tran k141_20387_1 314287.GB2207_11283 3.3e-209 593.0 COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,1RPU5@1236|Gammaproteobacteria,1J59H@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P COG0471 Di- and tricarboxylate transporters sdcS - - ko:K14445 - - - - ko00000,ko02000 2.A.47.1 - - Na_sulph_symp k141_20387_2 287986.DV20_39475 3.31e-19 92.0 COG0015@1|root,COG0015@2|Bacteria,2GM71@201174|Actinobacteria,4DZ4W@85010|Pseudonocardiales 201174|Actinobacteria F 3-carboxy-cis,cis-muconate cycloisomerase pcaB - 5.5.1.2 ko:K01857 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 - R03307 RC00902 ko00000,ko00001,ko01000 - - - ADSL_C,Lyase_1 k141_31193_2 910964.GEAM_2522 3.77e-28 103.0 COG3530@1|root,COG3530@2|Bacteria,1N7GT@1224|Proteobacteria,1SCBX@1236|Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria ypeB - - ko:K09954 - - - - ko00000 - - - QSregVF_b k141_31193_3 1163409.UUA_00870 3.12e-25 95.9 COG4572@1|root,COG4572@2|Bacteria,1N93H@1224|Proteobacteria,1S94E@1236|Gammaproteobacteria,1X8WH@135614|Xanthomonadales 135614|Xanthomonadales S Cation transport regulator chaB - - ko:K06197 - - - - ko00000 - - - ChaB k141_27533_1 218284.CCDN010000006_gene3551 8.24e-60 194.0 COG5002@1|root,COG5002@2|Bacteria,1V172@1239|Firmicutes,4IS5J@91061|Bacilli,1ZREC@1386|Bacillus 91061|Bacilli T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain saeS - 2.7.13.3 ko:K10681 ko02020,map02020 M00468 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA k141_26523_1 1294265.JCM21738_2912 7.82e-148 423.0 COG0189@1|root,COG0189@2|Bacteria,1UZ79@1239|Firmicutes,4HTI1@91061|Bacilli,1ZBQZ@1386|Bacillus 91061|Bacilli HJ COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase) - - - - - - - - - - - - ATPgrasp_YheCD k141_29918_1 218284.CCDN010000007_gene3817 2.03e-167 481.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,1ZBV0@1386|Bacillus 91061|Bacilli V ABC transporter ywjA - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran k141_2666_1 545693.BMQ_4790 7.97e-117 344.0 COG0137@1|root,COG0137@2|Bacteria,1TP3X@1239|Firmicutes,4HA1E@91061|Bacilli,1ZC1P@1386|Bacillus 91061|Bacilli E Belongs to the argininosuccinate synthase family. Type 1 subfamily argG GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 M00029,M00844,M00845 R01954 RC00380,RC00629 ko00000,ko00001,ko00002,ko01000,ko04147 - - iSB619.SA_RS04675 Arginosuc_synth k141_6317_1 1540257.JQMW01000009_gene3881 8.75e-32 117.0 COG2323@1|root,COG2323@2|Bacteria,1UZYT@1239|Firmicutes,24FP9@186801|Clostridia,36EZV@31979|Clostridiaceae 186801|Clostridia S Protein of unknown function (DUF421) - - - - - - - - - - - - DUF421 k141_28844_1 218284.CCDN010000005_gene3400 1.36e-167 479.0 COG0737@1|root,COG0737@2|Bacteria,1TQCW@1239|Firmicutes,4HAUC@91061|Bacilli,1ZCJ8@1386|Bacillus 91061|Bacilli F Belongs to the 5'-nucleotidase family yunD - 3.1.3.5 ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - 5_nucleotid_C,Metallophos k141_22844_1 998674.ATTE01000001_gene1932 3.78e-47 169.0 COG1027@1|root,COG1027@2|Bacteria,1R9JY@1224|Proteobacteria,1RP5Z@1236|Gammaproteobacteria,463WQ@72273|Thiotrichales 72273|Thiotrichales E Fumarase C C-terminus - - - - - - - - - - - - FumaraseC_C,Lyase_1,cNMP_binding k141_22844_2 1219065.VPR01S_11_01290 1.44e-19 79.7 2AWQ9@1|root,31NM8@2|Bacteria,1QKBV@1224|Proteobacteria,1TIFB@1236|Gammaproteobacteria,1XZ10@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_22844_3 1116375.VEJY3_22171 1.32e-117 337.0 COG1670@1|root,COG1670@2|Bacteria,1PDMH@1224|Proteobacteria,1RPZ4@1236|Gammaproteobacteria,1XVMW@135623|Vibrionales 135623|Vibrionales J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins speG GO:0000287,GO:0003674,GO:0003824,GO:0004145,GO:0005488,GO:0006576,GO:0006595,GO:0006598,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009056,GO:0009308,GO:0009310,GO:0009987,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0034641,GO:0042402,GO:0043167,GO:0043169,GO:0044106,GO:0044237,GO:0046872,GO:0071704,GO:1901564,GO:1901565,GO:1901575 2.3.1.57 ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 M00135 R01154 RC00004,RC00096 ko00000,ko00001,ko00002,ko01000 - - - Acetyltransf_3 k141_22844_4 223926.28808639 3.76e-158 447.0 2EAHZ@1|root,334M4@2|Bacteria,1NA8S@1224|Proteobacteria,1SFTQ@1236|Gammaproteobacteria,1XUHU@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_22844_5 1116375.VEJY3_22176 1.64e-220 613.0 COG2067@1|root,COG2067@2|Bacteria,1R3SS@1224|Proteobacteria,1S0X2@1236|Gammaproteobacteria,1XUNF@135623|Vibrionales 135623|Vibrionales I Outer membrane protein transport protein (OMPP1/FadL/TodX) - - - ko:K06076 - - - - ko00000,ko02000 1.B.9 - - Toluene_X k141_32253_1 1279017.AQYJ01000020_gene1256 4.74e-119 346.0 COG1028@1|root,COG1028@2|Bacteria,1MUUV@1224|Proteobacteria,1RMJU@1236|Gammaproteobacteria,466CG@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) ycdF - 1.5.1.33 ko:K03793 - - - - ko00000,ko01000 - - - adh_short_C2 k141_32253_3 1453501.JELR01000002_gene796 9.66e-93 275.0 COG0745@1|root,COG0745@2|Bacteria,1RD9E@1224|Proteobacteria,1S3PS@1236|Gammaproteobacteria,46DAR@72275|Alteromonadaceae 1236|Gammaproteobacteria T Helix-turn-helix domain - - - - - - - - - - - - HTH_17,Response_reg k141_32253_4 1279017.AQYJ01000020_gene1253 0.0 964.0 COG2719@1|root,COG2719@2|Bacteria,1MW6U@1224|Proteobacteria,1RPU2@1236|Gammaproteobacteria,464DM@72275|Alteromonadaceae 1236|Gammaproteobacteria S SpoVR family ycgB GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716 - ko:K06415 - - - - ko00000 - - - SpoVR k141_32253_6 1279017.AQYJ01000020_gene1251 0.0 1210.0 COG2766@1|root,COG2766@2|Bacteria,1MVW7@1224|Proteobacteria,1RNFJ@1236|Gammaproteobacteria,463Z0@72275|Alteromonadaceae 1236|Gammaproteobacteria T PrkA family serine protein kinase yeaG GO:0003674,GO:0003824,GO:0004672,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006995,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0042594,GO:0043170,GO:0043412,GO:0043562,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0140096,GO:1901564 - ko:K07180 - - - - ko00000 - - - AAA_PrkA,PrkA k141_32253_7 1042377.AFPJ01000043_gene949 1.66e-183 516.0 COG1087@1|root,COG1087@2|Bacteria,1MUHI@1224|Proteobacteria,1RMTU@1236|Gammaproteobacteria,464WV@72275|Alteromonadaceae 1236|Gammaproteobacteria M UDP-glucose 4-epimerase galE - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase,GDP_Man_Dehyd k141_12200_1 1033802.SSPSH_001513 3.59e-106 319.0 COG1503@1|root,COG1503@2|Bacteria,1MXX2@1224|Proteobacteria,1RXBB@1236|Gammaproteobacteria 1236|Gammaproteobacteria J translation release factor activity - - - - - - - - - - - - - k141_20388_1 1219072.VHA01S_024_00480 7.36e-88 273.0 COG4096@1|root,COG4096@2|Bacteria,1NUBD@1224|Proteobacteria,1SMR2@1236|Gammaproteobacteria,1XVF5@135623|Vibrionales 135623|Vibrionales V Domain of unknown function (DUF4145) - - - - - - - - - - - - DUF4145 k141_31194_1 498211.CJA_3013 2.82e-70 224.0 COG2211@1|root,COG2211@2|Bacteria,1MVUM@1224|Proteobacteria,1RP5J@1236|Gammaproteobacteria,1FGXW@10|Cellvibrio 1236|Gammaproteobacteria G MFS/sugar transport protein - - - ko:K03292 - - - - ko00000 2.A.2 - - MFS_2 k141_4969_1 1403313.AXBR01000021_gene3265 8.92e-28 108.0 28UJ1@1|root,2ZGPN@2|Bacteria,1W48G@1239|Firmicutes,4I25Y@91061|Bacilli,1ZE4R@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3993) - - - - - - - - - - - - DUF3993 k141_22845_1 333138.LQ50_11320 3.42e-76 242.0 COG3314@1|root,COG3314@2|Bacteria,1TR35@1239|Firmicutes,4HAB6@91061|Bacilli,1ZARZ@1386|Bacillus 91061|Bacilli S protein conserved in bacteria - - - - - - - - - - - - Gate k141_24010_1 379066.GAU_0505 1.15e-174 507.0 COG0843@1|root,COG0843@2|Bacteria,1ZSMG@142182|Gemmatimonadetes 142182|Gemmatimonadetes C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B - - 1.9.3.1 ko:K02274 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6 - - COX1 k141_24010_2 1304878.AUGD01000012_gene4119 5.27e-23 97.8 COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,1MWHZ@1224|Proteobacteria,2TRS5@28211|Alphaproteobacteria,3JYC7@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Cytochrome C oxidase subunit II, periplasmic domain - - 1.9.3.1 ko:K02275 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.4,3.D.4.6 - - COX2,Cytochrom_C k141_16907_2 1279017.AQYJ01000013_gene2989 5.62e-91 267.0 COG0080@1|root,COG0080@2|Bacteria,1RA2M@1224|Proteobacteria,1S22R@1236|Gammaproteobacteria,466G4@72275|Alteromonadaceae 1236|Gammaproteobacteria J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors rplK GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0015968,GO:0016043,GO:0019538,GO:0019843,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031667,GO:0031668,GO:0031669,GO:0032984,GO:0032991,GO:0033554,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0065003,GO:0070925,GO:0071496,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02867 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L11,Ribosomal_L11_N k141_27534_1 935836.JAEL01000123_gene2176 8.2e-88 265.0 COG4858@1|root,COG4858@2|Bacteria,1V8U0@1239|Firmicutes,4HIMP@91061|Bacilli,1ZFXH@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_12201_1 218284.CCDN010000001_gene1742 1.2e-78 241.0 COG0491@1|root,COG0491@2|Bacteria,1TR4H@1239|Firmicutes,4HBXR@91061|Bacilli,1ZDVA@1386|Bacillus 91061|Bacilli S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B k141_2667_4 148814.JI66_07095 4.77e-47 159.0 COG0863@1|root,COG0863@2|Bacteria,1V0ZF@1239|Firmicutes,4HCF9@91061|Bacilli,3F6WS@33958|Lactobacillaceae 91061|Bacilli L DNA methylase - - - - - - - - - - - - N6_N4_Mtase k141_9730_1 218284.CCDN010000004_gene3145 1.56e-41 144.0 COG2508@1|root,COG2508@2|Bacteria,1V649@1239|Firmicutes,4HHCD@91061|Bacilli,1ZH98@1386|Bacillus 91061|Bacilli QT PucR C-terminal helix-turn-helix domain lrp - - - - - - - - - - - HTH_30 k141_9730_2 218284.CCDN010000004_gene3144 1.43e-23 97.1 COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,4HAMQ@91061|Bacilli,1ZBDW@1386|Bacillus 91061|Bacilli P Belongs to the ABC transporter superfamily msmX - - ko:K10112 ko02010,map02010 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1 - - ABC_tran,TOBE,TOBE_2 k141_26526_1 493475.GARC_2758 1.57e-149 447.0 COG4774@1|root,COG4774@2|Bacteria,1NMCN@1224|Proteobacteria,1T3TQ@1236|Gammaproteobacteria,46AH5@72275|Alteromonadaceae 1236|Gammaproteobacteria P TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_33516_1 586416.GZ22_17765 2.48e-18 77.8 COG1358@1|root,COG1358@2|Bacteria,1VFD8@1239|Firmicutes,4HNXS@91061|Bacilli 91061|Bacilli J ribosomal protein rplGB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K07590 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L7Ae k141_33516_2 240302.BN982_04051 4.51e-95 306.0 COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,4HA24@91061|Bacilli,3NDG4@45667|Halobacillus 91061|Bacilli K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoC GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 k141_28846_2 218284.CCDN010000001_gene604 6.24e-84 255.0 COG0113@1|root,COG0113@2|Bacteria,1TP09@1239|Firmicutes,4HBQC@91061|Bacilli,1ZARK@1386|Bacillus 91061|Bacilli H Belongs to the ALAD family hemB GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00036 RC00918,RC01781 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ALAD k141_349_1 223926.28806570 6.11e-35 122.0 2AWET@1|root,31NAW@2|Bacteria,1QK1Y@1224|Proteobacteria,1TI4H@1236|Gammaproteobacteria,1XYCU@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_349_2 1116375.VEJY3_07475 5.62e-54 170.0 2A5FT@1|root,30U5T@2|Bacteria,1QK2X@1224|Proteobacteria,1TI5N@1236|Gammaproteobacteria,1XYFG@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_349_3 1116375.VEJY3_07480 8.16e-24 90.5 2AXX8@1|root,31PYF@2|Bacteria,1QMMA@1224|Proteobacteria,1TJWU@1236|Gammaproteobacteria,1Y1SQ@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_349_4 1116375.VEJY3_07485 2.96e-72 234.0 28M2E@1|root,2ZAGW@2|Bacteria,1R97D@1224|Proteobacteria,1RURR@1236|Gammaproteobacteria,1XVXB@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_19242_1 1294265.JCM21738_2914 1.7e-71 225.0 COG0189@1|root,COG0189@2|Bacteria,1U4ME@1239|Firmicutes,4HFD2@91061|Bacilli,1ZBNP@1386|Bacillus 91061|Bacilli HJ YheC/D like ATP-grasp yheC - - - - - - - - - - - ATPgrasp_YheCD k141_8578_2 1301098.PKB_3894 5.94e-17 77.4 COG1555@1|root,COG1555@2|Bacteria,1N6Q3@1224|Proteobacteria,1SC7U@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Competence protein ComEA comEA GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 - ko:K02237 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - HHH_3 k141_8578_3 1453501.JELR01000001_gene2059 8.11e-115 334.0 COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,1RNJR@1236|Gammaproteobacteria,464PB@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) pyrF GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 ko:K01591 ko00240,ko01100,map00240,map01100 M00051 R00965 RC00409 ko00000,ko00001,ko00002,ko01000 - - iECO103_1326.ECO103_1444,iECSF_1327.ECSF_1264,iSFV_1184.SFV_1294,iSF_1195.SF1285,iSFxv_1172.SFxv_1457,iS_1188.S1368,ic_1306.c1750 OMPdecase k141_24011_1 218284.CCDN010000002_gene2685 6.21e-150 439.0 COG3211@1|root,COG3211@2|Bacteria,1UYPE@1239|Firmicutes,4HCRC@91061|Bacilli,1ZDBG@1386|Bacillus 91061|Bacilli N Bacterial protein of unknown function (DUF839) - - - ko:K07093 - - - - ko00000 - - - DUF839 k141_16909_1 218284.CCDN010000004_gene3127 5.35e-89 271.0 COG0044@1|root,COG0044@2|Bacteria,1TPI6@1239|Firmicutes,4HAA9@91061|Bacilli,1ZE4P@1386|Bacillus 91061|Bacilli F Catalyzes the hydrolytic cleavage of a subset of L- isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation iadA - - ko:K01305 - - - - ko00000,ko01000,ko01002 - - - Amidohydro_1,Amidohydro_3 k141_4971_1 1453501.JELR01000002_gene1094 1.22e-156 446.0 COG2133@1|root,COG2133@2|Bacteria,1MVK5@1224|Proteobacteria,1RPE8@1236|Gammaproteobacteria,465NR@72275|Alteromonadaceae 1236|Gammaproteobacteria G Glucose / Sorbosone dehydrogenase - - - - - - - - - - - - GSDH k141_32256_1 218284.CCDN010000001_gene1774 2.31e-85 264.0 COG1457@1|root,COG1457@2|Bacteria,1UI7R@1239|Firmicutes,4ISUV@91061|Bacilli 91061|Bacilli F Spore germination protein - - - - - - - - - - - - Spore_permease k141_7408_2 406124.ACPC01000019_gene3051 1.43e-43 146.0 COG3030@1|root,COG3030@2|Bacteria,1VF5Y@1239|Firmicutes,4HKIJ@91061|Bacilli,1ZHSP@1386|Bacillus 91061|Bacilli S COG3030 Protein affecting phage T7 exclusion by the F plasmid fxsA - - ko:K07113 - - - - ko00000 - - - FxsA k141_25271_1 218284.CCDN010000001_gene1882 2.31e-191 550.0 COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,4H9Z3@91061|Bacilli,1ZB24@1386|Bacillus 91061|Bacilli J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction pnp GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 M00394 R00437,R00438,R00439,R00440 RC02795 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 - - - KH_1,PNPase,RNase_PH,RNase_PH_C,S1 k141_2697_1 1219076.N646_1069 2.83e-49 160.0 COG1335@1|root,COG1335@2|Bacteria,1MU5N@1224|Proteobacteria,1S7F3@1236|Gammaproteobacteria,1XWWK@135623|Vibrionales 135623|Vibrionales Q Isochorismatase family - - - - - - - - - - - - Isochorismatase k141_3916_1 1294265.JCM21738_262 1.41e-196 557.0 COG1196@1|root,COG1196@2|Bacteria,1TPJV@1239|Firmicutes,4HB89@91061|Bacilli,1ZAWM@1386|Bacillus 91061|Bacilli D Required for chromosome condensation and partitioning smc GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K03529 - - - - ko00000,ko03036 - - - SMC_N,SMC_hinge k141_33558_1 1116375.VEJY3_08275 1.14e-175 491.0 COG0388@1|root,COG0388@2|Bacteria,1MXG5@1224|Proteobacteria,1RP7S@1236|Gammaproteobacteria,1XSG7@135623|Vibrionales 135623|Vibrionales S Carbon-nitrogen hydrolase - - 3.5.1.53 ko:K12251 ko00330,ko01100,map00330,map01100 - R01152 RC00096 ko00000,ko00001,ko01000 - - - CN_hydrolase k141_20436_2 218284.CCDN010000009_gene4316 1.61e-80 241.0 2BNM3@1|root,32HA0@2|Bacteria,1V6TF@1239|Firmicutes,4HJ5U@91061|Bacilli,1ZHKY@1386|Bacillus 91061|Bacilli S Pathogenicity locus - - - - - - - - - - - - Cdd1 k141_26611_1 1453501.JELR01000001_gene2909 2.69e-114 341.0 2C3QV@1|root,2Z7YP@2|Bacteria,1MXAM@1224|Proteobacteria,1RNIA@1236|Gammaproteobacteria,4662K@72275|Alteromonadaceae 1236|Gammaproteobacteria S Alginate export - - - - - - - - - - - - Alginate_exp k141_26611_2 1453501.JELR01000001_gene2908 4.26e-85 259.0 COG1116@1|root,COG1116@2|Bacteria,1MUDV@1224|Proteobacteria,1RNEH@1236|Gammaproteobacteria,46520@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component nasD - - ko:K15578 ko00910,ko02010,map00910,map02010 M00438 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.16.1 - - ABC_tran k141_8629_1 1385513.N780_04220 1.59e-101 300.0 COG2746@1|root,COG2746@2|Bacteria,1V2QD@1239|Firmicutes,4HC3S@91061|Bacilli,2YBW1@289201|Pontibacillus 91061|Bacilli V Aminoglycoside 3-N-acetyltransferase - - 2.3.1.81 ko:K00662 - - - - ko00000,ko01000,ko01504 - - - Antibiotic_NAT k141_28882_1 983544.Lacal_0669 2.04e-07 53.9 COG1501@1|root,COG2819@1|root,COG1501@2|Bacteria,COG2819@2|Bacteria,4NE1H@976|Bacteroidetes,1HXZD@117743|Flavobacteriia 976|Bacteroidetes G Belongs to the glycosyl hydrolase 31 family - - 3.2.1.20 ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00028,R00801,R00802,R06087,R06088 RC00028,RC00049,RC00077 ko00000,ko00001,ko01000 - GH31 - DUF4968,DUF5110,Esterase,Gal_mutarotas_2,Glyco_hydro_31 k141_18193_1 1116375.VEJY3_14595 1.11e-127 375.0 COG0114@1|root,COG0114@2|Bacteria,1MUQI@1224|Proteobacteria,1RNUS@1236|Gammaproteobacteria,1XVJG@135623|Vibrionales 135623|Vibrionales C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate fumC - 4.2.1.2 ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 M00009,M00011,M00173,M00376 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - - FumaraseC_C,Lyase_1 k141_12271_1 498211.CJA_0275 6.51e-31 123.0 COG0845@1|root,COG0845@2|Bacteria,1R3R4@1224|Proteobacteria,1RNSG@1236|Gammaproteobacteria,1FHTP@10|Cellvibrio 1236|Gammaproteobacteria M Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - ko:K13408 ko04626,map04626 M00339 - - ko00000,ko00001,ko00002,ko02000,ko02044 8.A.1 - - Biotin_lipoyl_2,HlyD_3 k141_385_1 1116375.VEJY3_19111 5.73e-193 540.0 COG1398@1|root,COG1398@2|Bacteria,1N2MA@1224|Proteobacteria,1RM88@1236|Gammaproteobacteria,1XSEJ@135623|Vibrionales 135623|Vibrionales I desaturase - - 1.14.19.1 ko:K00507 ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212 - R02222 RC00917 ko00000,ko00001,ko01000,ko01004 - - - FA_desaturase k141_385_2 1116375.VEJY3_19106 2.43e-277 764.0 COG3069@1|root,COG3069@2|Bacteria,1MWBG@1224|Proteobacteria,1RQB2@1236|Gammaproteobacteria,1XTVS@135623|Vibrionales 135623|Vibrionales C C4-dicarboxylate transporter dcuC GO:0003674,GO:0005215,GO:0005310,GO:0005342,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015318,GO:0015556,GO:0015711,GO:0015740,GO:0015849,GO:0022857,GO:0034220,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0098656,GO:1903825,GO:1905039 - ko:K03326 - - - - ko00000,ko02000 2.A.61.1 - - DcuC k141_385_3 1280001.BAOA01000083_gene3651 1.25e-116 336.0 COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,1RP1N@1236|Gammaproteobacteria,1XXK8@135623|Vibrionales 135623|Vibrionales S LemA family - - - ko:K03744 - - - - ko00000 - - - LemA k141_385_4 223926.28808939 0.0 914.0 COG0501@1|root,COG0501@2|Bacteria,1MVU4@1224|Proteobacteria,1RPJ5@1236|Gammaproteobacteria,1XW2B@135623|Vibrionales 135623|Vibrionales O Peptidase family M48 - - - - - - - - - - - - Peptidase_M48 k141_385_5 1116375.VEJY3_19091 8.66e-65 199.0 2AW9Z@1|root,31N5F@2|Bacteria,1QJWV@1224|Proteobacteria,1THYP@1236|Gammaproteobacteria,1XXXD@135623|Vibrionales 135623|Vibrionales - - VVA0676 - - - - - - - - - - - - k141_385_6 945543.VIBR0546_13735 2.94e-71 225.0 COG2223@1|root,COG2223@2|Bacteria,1MWC7@1224|Proteobacteria,1S1CV@1236|Gammaproteobacteria,1XU0C@135623|Vibrionales 135623|Vibrionales P oxalate formate antiporter - - - - - - - - - - - - MFS_1 k141_1431_1 997296.PB1_03145 1e-79 265.0 COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,4HA3G@91061|Bacilli,1ZAVY@1386|Bacillus 91061|Bacilli T Diguanylate cyclase - - - - - - - - - - - - EAL,FIST,FIST_C,GAF_2,GGDEF,PAS,PAS_4,PAS_9,dCache_1 k141_26612_1 1385512.N784_04135 2.17e-56 183.0 COG0705@1|root,COG0705@2|Bacteria,1UYXN@1239|Firmicutes,4HCIU@91061|Bacilli,2Y8X5@289201|Pontibacillus 91061|Bacilli S peptidase ydcA - 3.4.21.105 ko:K19225 - - - - ko00000,ko01000,ko01002 - - - Rhomboid k141_5032_2 218284.CCDN010000001_gene181 1.01e-76 231.0 COG0517@1|root,COG0517@2|Bacteria,1V9HN@1239|Firmicutes,4HH3X@91061|Bacilli,1ZGY8@1386|Bacillus 91061|Bacilli S CBS domain ykuL - - - - - - - - - - - CBS k141_5032_3 218284.CCDN010000001_gene182 1.72e-47 152.0 COG4703@1|root,COG4703@2|Bacteria,1VKD0@1239|Firmicutes,4HRGC@91061|Bacilli,1ZI15@1386|Bacillus 91061|Bacilli S protein conserved in bacteria ykuJ - - - - - - - - - - - DUF1797 k141_21712_1 997296.PB1_07267 2.43e-14 68.6 2E36Q@1|root,32Y6E@2|Bacteria,1VEZV@1239|Firmicutes,4HQTK@91061|Bacilli,1ZIZ5@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF370) yaaB - - - - - - - - - - - DUF370 k141_22917_2 1123256.KB907938_gene622 1.01e-10 65.1 COG2272@1|root,COG2272@2|Bacteria,1MVQZ@1224|Proteobacteria,1RPFW@1236|Gammaproteobacteria,1X4ZQ@135614|Xanthomonadales 135614|Xanthomonadales I Belongs to the type-B carboxylesterase lipase family - - - - - - - - - - - - COesterase k141_9775_1 1195246.AGRI_05437 1.09e-17 89.4 2EBHX@1|root,335IC@2|Bacteria,1NCYG@1224|Proteobacteria,1SFBM@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_13418_1 1279017.AQYJ01000027_gene1920 1.2e-14 70.1 COG1380@1|root,COG1380@2|Bacteria 2|Bacteria S Effector of murein hydrolase LrgA lrgA GO:0000270,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0006810,GO:0008104,GO:0008150,GO:0008152,GO:0008565,GO:0009056,GO:0009057,GO:0009253,GO:0015031,GO:0015833,GO:0016020,GO:0030203,GO:0033036,GO:0042886,GO:0043170,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - ko:K05338,ko:K06518 ko02020,map02020 - - - ko00000,ko00001,ko02000 1.E.14.1,1.E.14.2 - - LrgA k141_37079_1 218284.CCDN010000001_gene200 3.03e-149 435.0 COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,4H9VD@91061|Bacilli,1ZAU2@1386|Bacillus 91061|Bacilli G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) ptsI GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0051179,GO:0051234,GO:0071702 2.7.3.9 ko:K08483 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 8.A.7 - - PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C k141_386_1 218284.CCDN010000003_gene2974 4.83e-93 282.0 COG3583@1|root,COG3584@1|root,COG3583@2|Bacteria,COG3584@2|Bacteria,1TTIK@1239|Firmicutes,4HC79@91061|Bacilli,1ZC0Q@1386|Bacillus 91061|Bacilli T protein conserved in bacteria yabE - - - - - - - - - - - 3D,DUF348,G5 k141_19298_2 1116375.VEJY3_16721 3.01e-299 820.0 COG0833@1|root,COG0833@2|Bacteria,1QU71@1224|Proteobacteria,1T1PB@1236|Gammaproteobacteria,1XV6A@135623|Vibrionales 135623|Vibrionales E Amino acid permease - - - ko:K16238 - - - - ko00000,ko02000 2.A.3.5 - - AA_permease_2 k141_6359_2 1122197.ATWI01000014_gene8 1.17e-39 137.0 2F2D0@1|root,33VAQ@2|Bacteria,1NV9U@1224|Proteobacteria,1SN8I@1236|Gammaproteobacteria,46B4M@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_9776_1 218284.CCDN010000001_gene132 4.23e-114 357.0 COG1038@1|root,COG1038@2|Bacteria,1UHP9@1239|Firmicutes,4IS56@91061|Bacilli,1ZC4R@1386|Bacillus 91061|Bacilli C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second pyc - 6.4.1.1 ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 M00173 R00344 RC00040,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,HMGL-like,PYC_OADA k141_7433_1 305900.GV64_17230 2.44e-27 103.0 COG0563@1|root,COG0563@2|Bacteria,1REQW@1224|Proteobacteria,1S67T@1236|Gammaproteobacteria,1XK1D@135619|Oceanospirillales 135619|Oceanospirillales F COG0563 Adenylate kinase and related kinases - - - - - - - - - - - - AAA_18 k141_7433_2 1085623.GNIT_2600 3.55e-31 120.0 COG3844@1|root,COG3844@2|Bacteria,1MUKN@1224|Proteobacteria,1RPY3@1236|Gammaproteobacteria,4647J@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively kynU - 3.7.1.3 ko:K01556 ko00380,ko01100,map00380,map01100 M00038 R00987,R02668,R03936 RC00284,RC00415 ko00000,ko00001,ko00002,ko01000 - - - Aminotran_5 k141_26613_2 674977.VMC_00620 7.83e-115 338.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RMMJ@1236|Gammaproteobacteria,1Y0CS@135623|Vibrionales 135623|Vibrionales C Acyl-CoA dehydrogenase, C-terminal domain - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_3920_1 555088.DealDRAFT_1179 1.4e-09 60.8 COG0557@1|root,COG0557@2|Bacteria,1TQ1G@1239|Firmicutes,247ZS@186801|Clostridia,42JM1@68298|Syntrophomonadaceae 186801|Clostridia J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs rnr - - ko:K12573 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03016,ko03019 - - - OB_RNB,RNB,S1 k141_3920_2 1379281.AVAG01000033_gene469 1.83e-17 75.1 COG2835@1|root,COG2835@2|Bacteria,1Q1BG@1224|Proteobacteria,42WTN@68525|delta/epsilon subdivisions,2WSI9@28221|Deltaproteobacteria,2MD2I@213115|Desulfovibrionales 28221|Deltaproteobacteria S Belongs to the UPF0434 family - - - ko:K09791 - - - - ko00000 - - - Trm112p k141_20439_1 218284.CCDN010000001_gene256 2.81e-83 251.0 COG1266@1|root,COG1266@2|Bacteria 2|Bacteria V CAAX protease self-immunity CP_0355 - - ko:K07052 - - - - ko00000 - - - Abi k141_1432_2 218284.CCDN010000002_gene2261 2.8e-24 97.4 28IN6@1|root,2Z8NK@2|Bacteria,1TR7N@1239|Firmicutes,4HBDQ@91061|Bacilli,1ZBTH@1386|Bacillus 91061|Bacilli S YfkD-like protein yfkD - - - - - - - - - - - YfkD k141_2699_1 1453501.JELR01000001_gene2064 1.11e-22 96.3 COG0697@1|root,COG0697@2|Bacteria,1MYHQ@1224|Proteobacteria,1S4AM@1236|Gammaproteobacteria,467NP@72275|Alteromonadaceae 1236|Gammaproteobacteria EG EamA-like transporter family - - - - - - - - - - - - EamA k141_2699_2 1453501.JELR01000001_gene2064 4.33e-29 112.0 COG0697@1|root,COG0697@2|Bacteria,1MYHQ@1224|Proteobacteria,1S4AM@1236|Gammaproteobacteria,467NP@72275|Alteromonadaceae 1236|Gammaproteobacteria EG EamA-like transporter family - - - - - - - - - - - - EamA k141_5034_1 218284.CCDN010000004_gene3039 5.45e-125 368.0 COG3428@1|root,COG3428@2|Bacteria,1TSRJ@1239|Firmicutes,4HB8P@91061|Bacilli,1ZBIF@1386|Bacillus 91061|Bacilli S Membrane ydbT - - ko:K08981 - - - - ko00000 - - - bPH_2 k141_28883_1 391165.GbCGDNIH1_1195 1.02e-08 60.8 COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,2TR5W@28211|Alphaproteobacteria,2JPJS@204441|Rhodospirillales 204441|Rhodospirillales E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) dapA - 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS k141_27561_1 1116375.VEJY3_03485 6.63e-85 274.0 COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,1XSZD@135623|Vibrionales 135623|Vibrionales P COG2217 Cation transport ATPase copA GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0051179,GO:0051234 3.6.3.54 ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - - E1-E2_ATPase,HMA,Hydrolase k141_27561_2 1280001.BAOA01000107_gene4694 0.0 946.0 COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,1RN3R@1236|Gammaproteobacteria,1XTNZ@135623|Vibrionales 135623|Vibrionales J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) gltX - 6.1.1.17 ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 - - - tRNA-synt_1c k141_27561_3 1116375.VEJY3_03495 1.23e-191 536.0 COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria,1N6EM@1224|Proteobacteria,1SBXG@1236|Gammaproteobacteria,1XU00@135623|Vibrionales 135623|Vibrionales M Belongs to the ompA family - - - ko:K03286 - - - - ko00000,ko02000 1.B.6 - - OmpA,OmpA_membrane k141_27561_4 1116375.VEJY3_03500 1.79e-115 331.0 2B0NW@1|root,31T0N@2|Bacteria,1QJDP@1224|Proteobacteria,1THCU@1236|Gammaproteobacteria,1XU2I@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_27561_5 1116375.VEJY3_03505 1.51e-243 672.0 28KVI@1|root,2ZAC4@2|Bacteria,1RBAQ@1224|Proteobacteria,1S3C3@1236|Gammaproteobacteria,1XV1Z@135623|Vibrionales 135623|Vibrionales N Flagellar assembly protein T, C-terminal domain flgT - - - - - - - - - - - FlgT_C,FlgT_M,FlgT_N k141_27561_6 1219076.N646_2917 1.4e-145 410.0 COG5616@1|root,COG5616@2|Bacteria,1R4DP@1224|Proteobacteria,1SAIF@1236|Gammaproteobacteria,1XTPR@135623|Vibrionales 135623|Vibrionales S Integral membrane protein VC2207 - - - - - - - - - - - - k141_27561_7 223926.28805755 1e-84 251.0 COG3018@1|root,COG3018@2|Bacteria,1N8R1@1224|Proteobacteria,1T0JQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria - - - ko:K09860 - - - - ko00000 - - - LPP20 k141_33561_1 1279017.AQYJ01000021_gene2779 3e-46 153.0 2EF35@1|root,338W8@2|Bacteria,1ND3I@1224|Proteobacteria,1SG26@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_21731_1 218284.CCDN010000001_gene705 1.92e-186 523.0 COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,4HAMU@91061|Bacilli,1ZD93@1386|Bacillus 91061|Bacilli E Cysteine synthase mccA GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004122,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008284,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016835,GO:0016836,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042127,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0065007,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.134,2.5.1.47 ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021,M00609 R00897,R03601,R04859,R10305 RC00020,RC00069,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS02385 PALP k141_6381_1 218284.CCDN010000006_gene3665 1.02e-134 391.0 COG1301@1|root,COG1301@2|Bacteria,1TPME@1239|Firmicutes,4HB4X@91061|Bacilli,1ZDVI@1386|Bacillus 91061|Bacilli C Sodium:dicarboxylate symporter family - - - - - - - - - - - - SDF k141_1457_1 318829.MGG_01014T0 6.71e-53 188.0 COG2759@1|root,KOG4230@2759|Eukaryota,38DB3@33154|Opisthokonta,3NVZV@4751|Fungi,3QKMW@4890|Ascomycota,213B4@147550|Sordariomycetes,41IEE@639021|Magnaporthales 4751|Fungi H C-1-tetrahydrofolate synthase ADE3 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0017076,GO:0017144,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046655,GO:0046656,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.5.1.5,3.5.4.9,6.3.4.3 ko:K00288 ko00670,ko01100,map00670,map01100 M00141 R00943,R01220,R01655 RC00026,RC00111,RC00202,RC00578 ko00000,ko00001,ko00002,ko01000,ko04147 - - - FTHFS,THF_DHG_CYH,THF_DHG_CYH_C k141_1457_2 243231.GSU1767 4.68e-34 131.0 COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,42MSB@68525|delta/epsilon subdivisions,2WJI6@28221|Deltaproteobacteria,43TW2@69541|Desulfuromonadales 28221|Deltaproteobacteria J Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseA - 3.1.11.6 ko:K03601 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_L,tRNA_anti_2 k141_15792_1 765914.ThisiDRAFT_2397 1.37e-85 266.0 COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,1RMYV@1236|Gammaproteobacteria,1WWCI@135613|Chromatiales 135613|Chromatiales O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis hslU - - ko:K03667 - - - - ko00000,ko03110 - - - AAA_2,ClpB_D2-small k141_26643_1 592028.GCWU000321_01032 1.89e-09 56.2 COG2185@1|root,COG2185@2|Bacteria,1V3QN@1239|Firmicutes,4H4FB@909932|Negativicutes 909932|Negativicutes I B12- binding domain protein - - 5.4.99.2 ko:K01849 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00375,M00376,M00741 R00833 RC00395 ko00000,ko00001,ko00002,ko01000 - - - B12-binding k141_26643_2 379066.GAU_1701 2.44e-95 293.0 COG1960@1|root,COG1960@2|Bacteria,1ZSVZ@142182|Gemmatimonadetes 142182|Gemmatimonadetes C Acyl-CoA dehydrogenase, C-terminal domain - - - ko:K18244 - - - - ko00000,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_35933_2 670487.Ocepr_0640 1.43e-19 87.8 COG3088@1|root,COG3088@2|Bacteria,1WJYG@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus O subunit of a heme lyase - - - ko:K02200 - - - - ko00000 - - - CcmH k141_32330_1 1294265.JCM21738_1413 7.62e-131 375.0 COG1027@1|root,COG1027@2|Bacteria,1TP3U@1239|Firmicutes,4HFM9@91061|Bacilli,1ZB5F@1386|Bacillus 91061|Bacilli E Aspartate ammonia-lyase aspA - 4.3.1.1 ko:K01744 ko00250,ko01100,map00250,map01100 - R00490 RC00316,RC02799 ko00000,ko00001,ko01000 - - - FumaraseC_C,Lyase_1 k141_20459_1 216142.LT40_06620 1.61e-38 131.0 COG2076@1|root,COG2076@2|Bacteria,1MZ6P@1224|Proteobacteria,1S8TD@1236|Gammaproteobacteria 1236|Gammaproteobacteria U multidrug resistance protein sugE - - ko:K11741 - - - - ko00000,ko02000 2.A.7.1 - - Multi_Drug_Res k141_8645_1 305900.GV64_01250 9.38e-150 433.0 COG0715@1|root,COG0715@2|Bacteria,1MWDN@1224|Proteobacteria,1RPUP@1236|Gammaproteobacteria,1XIGG@135619|Oceanospirillales 135619|Oceanospirillales P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components nrtC - - ko:K15576 ko00910,ko02010,map00910,map02010 M00438 - - ko00000,ko00001,ko00002,ko02000 3.A.1.16.1,3.A.1.16.2 - - NMT1_2 k141_24068_1 1279017.AQYJ01000024_gene861 0.0 1167.0 COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,1RM9X@1236|Gammaproteobacteria,46433@72275|Alteromonadaceae 1236|Gammaproteobacteria J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019538,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034645,GO:0036094,GO:0043021,GO:0043024,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:0097216,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N,IF2_assoc k141_24068_2 1279017.AQYJ01000024_gene860 1.91e-306 842.0 COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,1RNQS@1236|Gammaproteobacteria,4648A@72275|Alteromonadaceae 1236|Gammaproteobacteria K Participates in both transcription termination and antitermination nusA GO:0001000,GO:0001121,GO:0001125,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0019904,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043175,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - ko:K02600 - - - - ko00000,ko03009,ko03021 - - - HHH_5,KH_5,NusA_N,S1 k141_9813_1 1116375.VEJY3_07850 1.62e-276 756.0 COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,1RNT1@1236|Gammaproteobacteria,1XUU8@135623|Vibrionales 135623|Vibrionales C Belongs to the citrate synthase family prpC - 2.3.3.5 ko:K01659 ko00640,map00640 - R00931 RC00004,RC00406,RC02827 ko00000,ko00001,ko01000 - - - Citrate_synt k141_9813_2 223926.28806637 2.04e-244 692.0 COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,1RN5I@1236|Gammaproteobacteria,1XTEH@135623|Vibrionales 135623|Vibrionales C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate acnA - 4.2.1.117 ko:K20455 ko00640,map00640 - R11263 RC01152 ko00000,ko00001,ko01000 - - - Aconitase,Aconitase_C k141_12304_1 1288298.rosmuc_00179 2.09e-68 212.0 COG0689@1|root,COG0689@2|Bacteria,1MVFZ@1224|Proteobacteria,2TRMC@28211|Alphaproteobacteria,46PK0@74030|Roseovarius 28211|Alphaproteobacteria J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates rph GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 ko:K00989 - - - - ko00000,ko01000,ko03016 - - - RNase_PH,RNase_PH_C k141_12304_2 314265.R2601_14735 0.000117 43.9 COG1420@1|root,COG1420@2|Bacteria,1MVX4@1224|Proteobacteria,2TRUF@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons hrcA - - ko:K03705 - - - - ko00000,ko03000 - - - HrcA,HrcA_DNA-bdg k141_13455_1 218284.CCDN010000010_gene4375 8.46e-108 315.0 COG2813@1|root,COG2813@2|Bacteria,1V1BG@1239|Firmicutes,4HHCA@91061|Bacilli,1ZBPR@1386|Bacillus 91061|Bacilli J Methyltransferase rsmC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 2.1.1.172 ko:K00564 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - MTS k141_13455_2 218284.CCDN010000010_gene4374 1.1e-296 840.0 COG0085@1|root,COG0085@2|Bacteria,1TP96@1239|Firmicutes,4H9PK@91061|Bacilli,1ZBPC@1386|Bacillus 91061|Bacilli K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoB GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 k141_22934_1 1279017.AQYJ01000026_gene370 1.37e-126 364.0 COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,1RMS5@1236|Gammaproteobacteria,464QE@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate pdxJ GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 ko:K03474 ko00750,ko01100,map00750,map01100 M00124 R05838 RC01476 ko00000,ko00001,ko00002,ko01000 - - - PdxJ k141_22934_2 377629.TERTU_2477 3.4e-74 229.0 COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,1RP9U@1236|Gammaproteobacteria,2PNIE@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria M Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ppiA GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005623,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 ko:K01802,ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 - - - ko00000,ko00001,ko01000,ko03110,ko04147 - - - Pro_isomerase k141_22934_3 1453501.JELR01000001_gene1911 2.56e-98 292.0 COG3807@1|root,COG3807@2|Bacteria,1QWZW@1224|Proteobacteria,1T31J@1236|Gammaproteobacteria,467XH@72275|Alteromonadaceae 1236|Gammaproteobacteria S SH3 domain protein ygiM - - ko:K07184 - - - - ko00000 - - - SH3_3 k141_22934_4 498211.CJA_1794 7.95e-50 160.0 COG2350@1|root,COG2350@2|Bacteria,1MZ9Z@1224|Proteobacteria,1S8UC@1236|Gammaproteobacteria,1FHIY@10|Cellvibrio 1236|Gammaproteobacteria S YCII-related domain yciI GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K05527,ko:K09780 - - - - ko00000,ko03000 - - - YCII k141_22934_5 1453501.JELR01000001_gene1913 1.46e-126 365.0 2CH0A@1|root,2ZANK@2|Bacteria,1R6U4@1224|Proteobacteria,1RQ3J@1236|Gammaproteobacteria,466JM@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_22934_6 1279017.AQYJ01000026_gene365 4.06e-133 389.0 COG0613@1|root,COG0613@2|Bacteria,1MWIH@1224|Proteobacteria,1RNCG@1236|Gammaproteobacteria,466MQ@72275|Alteromonadaceae 1236|Gammaproteobacteria S metal-dependent phosphoesterases (PHP family) trpH GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004532,GO:0004534,GO:0004536,GO:0004540,GO:0005488,GO:0006139,GO:0006259,GO:0006521,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008252,GO:0008409,GO:0009987,GO:0010565,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016796,GO:0016895,GO:0016896,GO:0019222,GO:0030145,GO:0031323,GO:0033238,GO:0034641,GO:0035312,GO:0042578,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090305,GO:0090357,GO:0090501,GO:0090503,GO:0140097,GO:0140098,GO:1901360 3.1.3.97 ko:K07053 - - R00188,R11188 RC00078 ko00000,ko01000 - - - PHP k141_22934_7 1042377.AFPJ01000037_gene2925 1.67e-130 372.0 COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,1RNU8@1236|Gammaproteobacteria,465FZ@72275|Alteromonadaceae 1236|Gammaproteobacteria J Belongs to the SUA5 family yciO GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - - - - - - - - - - Sua5_yciO_yrdC k141_22934_8 1042377.AFPJ01000037_gene2924 4.77e-157 454.0 COG1354@1|root,COG1354@2|Bacteria,1MVCN@1224|Proteobacteria,1RNBB@1236|Gammaproteobacteria,465A1@72275|Alteromonadaceae 1236|Gammaproteobacteria D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves scpA - - ko:K05896 - - - - ko00000,ko03036 - - - SMC_ScpA k141_22934_9 1042377.AFPJ01000037_gene2923 1.52e-113 343.0 COG1386@1|root,COG1386@2|Bacteria,1PUA6@1224|Proteobacteria,1RNXE@1236|Gammaproteobacteria,4649H@72275|Alteromonadaceae 1236|Gammaproteobacteria D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves scpB - - ko:K06024 - - - - ko00000,ko03036 - - - SMC_ScpB k141_22934_11 1453501.JELR01000001_gene1919 4.71e-80 246.0 COG3832@1|root,COG3832@2|Bacteria,1RDMX@1224|Proteobacteria,1S914@1236|Gammaproteobacteria,46DJU@72275|Alteromonadaceae 1236|Gammaproteobacteria S Polyketide cyclase / dehydrase and lipid transport - - - - - - - - - - - - GyrI-like,Polyketide_cyc2 k141_22934_12 1279017.AQYJ01000026_gene359 5.55e-217 612.0 COG0642@1|root,COG2205@2|Bacteria,1N17V@1224|Proteobacteria,1T1JX@1236|Gammaproteobacteria,466X6@72275|Alteromonadaceae 1236|Gammaproteobacteria T Signal transduction histidine kinase cpxA - 2.7.13.3 ko:K07640 ko01503,ko02020,map01503,map02020 M00447,M00727,M00728 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA k141_22934_13 1279017.AQYJ01000026_gene358 2.11e-126 364.0 COG0745@1|root,COG0745@2|Bacteria,1MVCB@1224|Proteobacteria,1RMW7@1236|Gammaproteobacteria,466IP@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain cpxR - - ko:K07662 ko01503,ko02020,map01503,map02020 M00447,M00727,M00728 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C k141_22934_14 1453501.JELR01000001_gene1922 8.76e-27 106.0 COG3678@1|root,COG3678@2|Bacteria 2|Bacteria NPTU ATP-independent chaperone mediated protein folding - - - ko:K06006 - - - - ko00000,ko03110 - - - LTXXQ k141_22934_15 1279017.AQYJ01000026_gene356 4.7e-112 323.0 COG0716@1|root,COG0716@2|Bacteria,1MX7F@1224|Proteobacteria,1RMNT@1236|Gammaproteobacteria,465A6@72275|Alteromonadaceae 1236|Gammaproteobacteria C Low-potential electron donor to a number of redox enzymes fldA - - ko:K03839 - - - - ko00000 - - - Flavodoxin_1 k141_22934_16 1279017.AQYJ01000026_gene355 1.88e-59 186.0 2AGM5@1|root,34481@2|Bacteria,1P2XN@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_22934_17 1453501.JELR01000001_gene1925 0.0 887.0 COG1506@1|root,COG1506@2|Bacteria,1MUJ3@1224|Proteobacteria,1RPAW@1236|Gammaproteobacteria,464D0@72275|Alteromonadaceae 1236|Gammaproteobacteria E X-Pro dipeptidyl-peptidase (S15 family) - - - - - - - - - - - - Peptidase_S9 k141_22934_19 908612.HMPREF9720_1814 4.99e-56 197.0 COG0477@1|root,COG2814@2|Bacteria,4NGAV@976|Bacteroidetes,2G0JU@200643|Bacteroidia 976|Bacteroidetes EGP Transmembrane secretion effector - - - ko:K08217 - - - - br01600,ko00000,ko01504,ko02000 2.A.1.21.1,2.A.1.21.22 - - MFS_1,MFS_3 k141_5066_1 1219072.VHA01S_008_00750 2.26e-96 291.0 COG3203@1|root,COG3203@2|Bacteria,1QTIE@1224|Proteobacteria,1SWVJ@1236|Gammaproteobacteria,1XSH5@135623|Vibrionales 135623|Vibrionales M COG3203 Outer membrane protein (porin) - - - - - - - - - - - - Porin_4 k141_5066_2 1280001.BAOA01000051_gene1474 1.02e-129 373.0 COG1561@1|root,COG1561@2|Bacteria,1MWRA@1224|Proteobacteria,1RMAB@1236|Gammaproteobacteria,1XSZ4@135623|Vibrionales 135623|Vibrionales S stress-induced protein - - - - - - - - - - - - DUF1732,YicC_N k141_9814_1 1036674.A28LD_1110 4.41e-32 117.0 COG3038@1|root,COG3038@2|Bacteria,1REWF@1224|Proteobacteria,1S5QE@1236|Gammaproteobacteria,2QG9W@267893|Idiomarinaceae 1236|Gammaproteobacteria C Prokaryotic cytochrome b561 - - - ko:K12262 - - - - ko00000 - - - Ni_hydr_CYTB k141_9814_2 1218084.BBJK01000005_gene678 5.18e-16 78.6 COG0753@1|root,COG0753@2|Bacteria,1MUXZ@1224|Proteobacteria,2VGZA@28216|Betaproteobacteria,1JZQW@119060|Burkholderiaceae 28216|Betaproteobacteria C Has an organic peroxide-dependent peroxidase activity - - 1.11.1.6 ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 M00532 R00009,R00602,R02670 RC00034,RC00767,RC02141,RC02755 ko00000,ko00001,ko00002,ko01000 - - - Catalase k141_13456_1 42565.FP66_03470 4.26e-119 358.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPES@1236|Gammaproteobacteria,1XH5X@135619|Oceanospirillales 135619|Oceanospirillales S ABC transporter ATP-binding protein - - - ko:K06158 - - - - ko00000,ko03012 - - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn k141_37097_1 1279017.AQYJ01000029_gene3416 3.62e-313 865.0 COG2234@1|root,COG2234@2|Bacteria,1MV86@1224|Proteobacteria,1RNNQ@1236|Gammaproteobacteria,464MC@72275|Alteromonadaceae 1236|Gammaproteobacteria S Peptidase family M28 - - - - - - - - - - - - PA,Peptidase_M28 k141_22935_1 218284.CCDN010000001_gene1207 8.85e-47 155.0 COG1404@1|root,COG1404@2|Bacteria,1V3SC@1239|Firmicutes,4HGZF@91061|Bacilli,1ZGVY@1386|Bacillus 91061|Bacilli O Domain of unknown function (DUF4397) - - - - - - - - - - - - DUF4397 k141_6382_1 717606.PaecuDRAFT_3644 1.96e-91 286.0 COG0504@1|root,COG0504@2|Bacteria,1TP34@1239|Firmicutes,4H9X6@91061|Bacilli,26RTB@186822|Paenibacillaceae 91061|Bacilli F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates pyrG - 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 - - - CTP_synth_N,GATase k141_21732_1 1279017.AQYJ01000026_gene324 6.72e-102 298.0 COG0806@1|root,COG0806@2|Bacteria,1MWQR@1224|Proteobacteria,1RNJ2@1236|Gammaproteobacteria,467CY@72275|Alteromonadaceae 1236|Gammaproteobacteria J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes rimM GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 - ko:K02860 - - - - ko00000,ko03009 - - - PRC,RimM k141_25292_2 1279017.AQYJ01000027_gene1809 1.17e-111 325.0 COG0357@1|root,COG0357@2|Bacteria,1MY0K@1224|Proteobacteria,1RMRZ@1236|Gammaproteobacteria,466SB@72275|Alteromonadaceae 1236|Gammaproteobacteria J Specifically methylates the N7 position of guanine in position 527 of 16S rRNA rsmG GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 ko:K03501 - - - - ko00000,ko01000,ko03009,ko03036 - - - GidB k141_2722_1 765869.BDW_05545 2.53e-44 159.0 COG5557@1|root,COG5557@2|Bacteria,1PFX4@1224|Proteobacteria,42PIE@68525|delta/epsilon subdivisions,2MTQJ@213481|Bdellovibrionales,2WM3C@28221|Deltaproteobacteria 213481|Bdellovibrionales C Polysulphide reductase moz - - ko:K00185 - - - - ko00000 5.A.3 - - DUF3341,NrfD k141_34786_3 2340.JV46_04030 9.63e-15 72.0 COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,1S237@1236|Gammaproteobacteria,1J9MC@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P Reversible hydration of carbon dioxide cynT - 4.2.1.1 ko:K01673 ko00910,map00910 - R00132,R10092 RC02807 ko00000,ko00001,ko01000 - - - Pro_CA k141_9816_1 1294265.JCM21738_2816 2.49e-147 419.0 COG0665@1|root,COG0665@2|Bacteria,1TQTF@1239|Firmicutes,4HA0F@91061|Bacilli,1ZBU6@1386|Bacillus 91061|Bacilli E COG0665 Glycine D-amino acid oxidases (deaminating) yurR GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0044424,GO:0044464,GO:0055114 1.4.5.1 ko:K00285 ko00360,map00360 - R01374,R09493 RC00006,RC00025 ko00000,ko00001,ko01000 - - - DAO k141_27579_1 1144275.COCOR_01921 1.81e-73 231.0 COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,42M98@68525|delta/epsilon subdivisions,2WMKB@28221|Deltaproteobacteria,2YXV7@29|Myxococcales 28221|Deltaproteobacteria L HTH-like domain - - - ko:K07497 - - - - ko00000 - - - HTH_21,HTH_Tnp_1,rve,rve_3 k141_3966_1 218284.CCDN010000008_gene4182 2.63e-117 348.0 COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,4HADT@91061|Bacilli,1ZAZA@1386|Bacillus 91061|Bacilli KT Transcriptional regulator - - - - - - - - - - - - HTH_8,PAS,PAS_9,Sigma54_activat k141_24069_2 1121904.ARBP01000048_gene4108 4.11e-06 52.0 COG5485@1|root,COG5485@2|Bacteria 2|Bacteria S SnoaL-like polyketide cyclase - - - - - - - - - - - - SnoaL k141_24069_3 383372.Rcas_3672 1.81e-28 112.0 COG0626@1|root,COG0626@2|Bacteria,2G7Q6@200795|Chloroflexi,3770M@32061|Chloroflexia 32061|Chloroflexia H PFAM Cys Met metabolism pyridoxal-phosphate-dependent - - 4.4.1.11 ko:K01761 ko00270,ko00450,map00270,map00450 - R00654,R04770 RC00196,RC00348,RC01209,RC01210 ko00000,ko00001,ko01000 - - - Cys_Met_Meta_PP k141_12306_1 218284.CCDN010000010_gene4393 1.65e-190 536.0 COG1066@1|root,COG1066@2|Bacteria,1TQ7Y@1239|Firmicutes,4H9YC@91061|Bacilli,1ZB8H@1386|Bacillus 91061|Bacilli O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function radA - - ko:K04485 - - - - ko00000,ko03400 - - - AAA_25,ATPase,ChlI k141_31254_1 1268237.G114_17105 4.06e-29 117.0 COG1505@1|root,COG1505@2|Bacteria,1NZ7N@1224|Proteobacteria,1T1KJ@1236|Gammaproteobacteria,1Y6MH@135624|Aeromonadales 135624|Aeromonadales E Prolyl oligopeptidase, N-terminal beta-propeller domain - - 3.4.21.26 ko:K01322 ko04614,map04614 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S9,Peptidase_S9_N k141_21733_1 42565.FP66_07215 1.1e-17 79.0 COG1028@1|root,COG1028@2|Bacteria,1MUUV@1224|Proteobacteria,1RPGM@1236|Gammaproteobacteria,1XJ6R@135619|Oceanospirillales 135619|Oceanospirillales IQ reductase - - 1.5.1.3,1.5.1.50 ko:K13938 ko00670,ko00790,ko01100,map00670,map00790,map01100 - R00936,R00939,R11019 RC00109,RC03327 ko00000,ko00001,ko01000 - - - adh_short,adh_short_C2 k141_6383_1 1347086.CCBA010000022_gene2867 5.73e-33 128.0 COG1404@1|root,COG1404@2|Bacteria,1TSRI@1239|Firmicutes,4HBFB@91061|Bacilli,1ZCQD@1386|Bacillus 91061|Bacilli O Subtilase family - - 3.4.21.62 ko:K01342 ko02024,map02024 - - - ko00000,ko00001,ko01000,ko01002,ko03110 - - - Peptidase_S8 k141_34787_1 388399.SSE37_17875 3.93e-37 135.0 COG2931@1|root,COG2931@2|Bacteria,1R4PX@1224|Proteobacteria,2TUD5@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q Hint domain - - - - - - - - - - - - Hint_2 k141_34787_2 1116232.AHBF01000017_gene3999 3.93e-12 64.7 COG0454@1|root,COG0456@2|Bacteria,2IHR1@201174|Actinobacteria 201174|Actinobacteria K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10,Acetyltransf_7 k141_3967_2 218284.CCDN010000002_gene1991 4.77e-35 124.0 COG0299@1|root,COG0299@2|Bacteria,1V3RJ@1239|Firmicutes,4HGY5@91061|Bacilli,1ZFSE@1386|Bacillus 91061|Bacilli F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate purN - 2.1.2.2 ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04325,R04326 RC00026,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 - - - Formyl_trans_N k141_19319_1 1279017.AQYJ01000027_gene1905 4.64e-102 296.0 COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,1S41J@1236|Gammaproteobacteria,466Y2@72275|Alteromonadaceae 1236|Gammaproteobacteria H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate coaD GO:0003674,GO:0003824,GO:0004595,GO:0005488,GO:0005515,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 ko:K00954 ko00770,ko01100,map00770,map01100 M00120 R03035 RC00002 ko00000,ko00001,ko00002,ko01000 - - iPC815.YPO0053,iSDY_1059.SDY_4064 CTP_transf_like k141_19319_2 1279017.AQYJ01000027_gene1906 1.12e-88 265.0 COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,1RN21@1236|Gammaproteobacteria,467AQ@72275|Alteromonadaceae 1236|Gammaproteobacteria L Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle rsmD GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052913,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.171 ko:K08316 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - Cons_hypoth95 k141_19319_3 1042377.AFPJ01000028_gene2269 3.22e-116 348.0 COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,1RNIN@1236|Gammaproteobacteria,464WP@72275|Alteromonadaceae 1236|Gammaproteobacteria U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components ftsY GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019897,GO:0019898,GO:0031224,GO:0031226,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033036,GO:0033365,GO:0034613,GO:0035639,GO:0036094,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2,3.A.5.7 - - SRP54,SRP54_N k141_37099_1 1294265.JCM21738_405 1.51e-183 523.0 COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1TSSC@1239|Firmicutes,4HA8C@91061|Bacilli,1ZBA6@1386|Bacillus 91061|Bacilli C COG1014 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, gamma subunit korA - 1.2.7.11,1.2.7.3 ko:K00174 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - PFOR_II,POR,POR_N k141_12339_2 1134474.O59_004034 5.49e-69 218.0 COG2846@1|root,COG2846@2|Bacteria,1MVCQ@1224|Proteobacteria,1RPY6@1236|Gammaproteobacteria 1236|Gammaproteobacteria D Di-iron-containing protein involved in the repair of iron-sulfur clusters ytfE GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0018282,GO:0018283,GO:0019538,GO:0022607,GO:0030091,GO:0031163,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0071704,GO:0071840,GO:1901564 - ko:K07322 - - - - ko00000 - - iECED1_1282.ECED1_5068,iECH74115_1262.ECH74115_5726,iECSP_1301.ECSP_5311,iECs_1301.ECs5187,iG2583_1286.G2583_5039,iZ_1308.Z5820 Hemerythrin,ScdA_N k141_35943_1 218284.CCDN010000002_gene2396 4.01e-90 278.0 COG0697@1|root,COG0697@2|Bacteria,1TP7K@1239|Firmicutes,4HAH1@91061|Bacilli,1ZBEF@1386|Bacillus 91061|Bacilli EG Spore germination protein - - - ko:K06295 - - - - ko00000 - - - GerA k141_35943_2 218284.CCDN010000002_gene2395 2.84e-71 226.0 2DBJR@1|root,2Z9N7@2|Bacteria,1TRSN@1239|Firmicutes,4HCDI@91061|Bacilli,1ZN92@1386|Bacillus 91061|Bacilli S Spore germination B3/ GerAC like, C-terminal - - - - - - - - - - - - Spore_GerAC k141_20482_1 1294265.JCM21738_1805 1.11e-139 402.0 COG0552@1|root,COG0552@2|Bacteria,1TR66@1239|Firmicutes,4HDEI@91061|Bacilli,1ZDQ2@1386|Bacillus 91061|Bacilli U protein localization to endoplasmic reticulum - - - - - - - - - - - - - k141_8676_1 518766.Rmar_1305 4.43e-24 101.0 COG1186@1|root,COG1186@2|Bacteria,4NEN1@976|Bacteroidetes,1FINB@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA prfB - - ko:K02836 - - - - ko00000,ko03012 - - - PCRF,RF-1 k141_9851_1 218284.CCDN010000005_gene3470 1.82e-84 263.0 COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,4HC5M@91061|Bacilli,1ZB0M@1386|Bacillus 91061|Bacilli KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains rocR GO:0006082,GO:0006355,GO:0006520,GO:0006525,GO:0006807,GO:0008150,GO:0008152,GO:0009064,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031326,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1901564,GO:1901605,GO:1903506,GO:2000112,GO:2001141 - ko:K06714 - - - - ko00000,ko03000 - - - HTH_8,PAS,PAS_4,PAS_9,Sigma54_activat k141_11031_1 999549.KI421514_gene126 4.51e-108 323.0 COG0683@1|root,COG0683@2|Bacteria,1MUCB@1224|Proteobacteria,2TRWV@28211|Alphaproteobacteria,280JI@191028|Leisingera 28211|Alphaproteobacteria E Periplasmic binding protein domain - - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6,TAT_signal k141_24094_1 866895.HBHAL_1195 6.62e-75 243.0 COG4987@1|root,COG4987@2|Bacteria,1UHN5@1239|Firmicutes,4HAAB@91061|Bacilli,3NE6P@45667|Halobacillus 91061|Bacilli V ABC transporter transmembrane region cydC - - ko:K16012 ko02010,map02010 - - - ko00000,ko00001,ko02000 3.A.1.129 - - ABC_membrane,ABC_tran k141_6404_1 218284.CCDN010000003_gene2984 7.89e-153 439.0 COG1207@1|root,COG1207@2|Bacteria,1TP88@1239|Firmicutes,4H9V5@91061|Bacilli,1ZAVH@1386|Bacillus 91061|Bacilli M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain glmU GO:0000270,GO:0000271,GO:0003674,GO:0003824,GO:0003977,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006629,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0030203,GO:0033692,GO:0034637,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509 2.3.1.157,2.7.7.23 ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00362 R00416,R05332 RC00002,RC00004,RC00166 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transf_3,NTP_transferase k141_6404_2 665952.HMPREF1015_02796 9.27e-62 190.0 COG2088@1|root,COG2088@2|Bacteria,1V9ZG@1239|Firmicutes,4HIPT@91061|Bacilli,1ZGXK@1386|Bacillus 91061|Bacilli D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation spoVG GO:0000003,GO:0008150,GO:0019954,GO:0030436,GO:0032502,GO:0043934 - ko:K06412 - - - - ko00000 - - - SpoVG k141_33619_1 1279017.AQYJ01000026_gene228 0.0 1028.0 COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,1RN05@1236|Gammaproteobacteria,464MR@72275|Alteromonadaceae 1236|Gammaproteobacteria S Insulinase (Peptidase family M16) ptrA - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C k141_37119_1 796606.BMMGA3_13710 5.62e-91 275.0 COG1575@1|root,COG1575@2|Bacteria,1TSZV@1239|Firmicutes,4HA68@91061|Bacilli,1ZB6F@1386|Bacillus 91061|Bacilli H Belongs to the MenA family. Type 1 subfamily menA GO:0003674,GO:0003824,GO:0004659,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006775,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016765,GO:0032194,GO:0042180,GO:0042181,GO:0042362,GO:0042371,GO:0042373,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.74 ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R05617,R06858,R10757 RC02935,RC02936,RC03264 ko00000,ko00001,ko00002,ko01000,ko01006 - - - UbiA k141_8677_1 218284.CCDN010000001_gene225 4.5e-59 186.0 COG3874@1|root,COG3874@2|Bacteria,1V6H7@1239|Firmicutes,4HIG7@91061|Bacilli,1ZG9C@1386|Bacillus 91061|Bacilli S Sporulation protein YtfJ ytfJ - - - - - - - - - - - Spore_YtfJ k141_7450_2 1294265.JCM21738_4606 2.64e-28 110.0 COG1066@1|root,COG1066@2|Bacteria,1TQ7Y@1239|Firmicutes,4H9YC@91061|Bacilli,1ZB8H@1386|Bacillus 91061|Bacilli O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function radA - - ko:K04485 - - - - ko00000,ko03400 - - - AAA_25,ATPase,ChlI k141_28895_1 1405.DJ92_739 3.27e-100 295.0 COG1309@1|root,COG1309@2|Bacteria,1VCV2@1239|Firmicutes,4HN1G@91061|Bacilli,1ZHKV@1386|Bacillus 91061|Bacilli K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N k141_26674_1 1496688.ER33_02825 7.1e-74 241.0 COG3675@1|root,COG3675@2|Bacteria,1G7WY@1117|Cyanobacteria,22TH3@167375|Cyanobium 1117|Cyanobacteria I Lipase (class 3) - - 3.1.1.3 ko:K01046 ko00561,ko01100,map00561,map01100 M00098 R02250,R02687 RC00020,RC00037,RC00041,RC00094 ko00000,ko00001,ko00002,ko01000 - - - Lipase_3 k141_29973_1 55601.VANGNB10_cI2605 7.53e-152 434.0 COG0582@1|root,COG0582@2|Bacteria,1R96H@1224|Proteobacteria,1RZPN@1236|Gammaproteobacteria,1XWU0@135623|Vibrionales 135623|Vibrionales L Phage integrase family - - - - - - - - - - - - Phage_integrase k141_3991_1 1280954.HPO_07127 1.56e-59 207.0 COG1629@1|root,COG4771@2|Bacteria,1MWKN@1224|Proteobacteria,2TTI2@28211|Alphaproteobacteria,43WMH@69657|Hyphomonadaceae 28211|Alphaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec k141_3991_2 1453501.JELR01000002_gene1149 1.17e-27 102.0 COG4628@1|root,COG4628@2|Bacteria,1N7DG@1224|Proteobacteria,1SCBE@1236|Gammaproteobacteria,467Z9@72275|Alteromonadaceae 1236|Gammaproteobacteria S DNA-binding protein VF530 - GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0097159,GO:1901363 - - - - - - - - - - VF530 k141_21748_1 626887.J057_05826 2.48e-92 286.0 COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,1MUDN@1224|Proteobacteria,1RMMG@1236|Gammaproteobacteria,465X6@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0491 Zn-dependent hydrolases, including glyoxylases - - 3.1.2.6 ko:K01069 ko00620,map00620 - R01736 RC00004,RC00137 ko00000,ko00001,ko01000 - - - Lactamase_B,Rhodanese k141_12342_1 1294265.JCM21738_3381 1.89e-07 48.5 2BKD4@1|root,32ETR@2|Bacteria,1UAMR@1239|Firmicutes,4IM0B@91061|Bacilli,1ZIKW@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_12342_2 1294265.JCM21738_3382 8.99e-63 199.0 COG1988@1|root,COG1988@2|Bacteria,1TT3S@1239|Firmicutes,4HDWS@91061|Bacilli,1ZD0N@1386|Bacillus 91061|Bacilli S LexA-binding, inner membrane-associated putative hydrolase - - - ko:K07038 - - - - ko00000 - - - YdjM k141_8678_1 1385935.N836_02685 1.18e-51 175.0 COG3367@1|root,COG3367@2|Bacteria,1GA7A@1117|Cyanobacteria 1117|Cyanobacteria S COGs COG3367 conserved - - - - - - - - - - - - - k141_13490_1 1453501.JELR01000001_gene3133 1.58e-101 304.0 COG0598@1|root,COG0598@2|Bacteria,1MW8W@1224|Proteobacteria,1RRTZ@1236|Gammaproteobacteria,464S0@72275|Alteromonadaceae 1236|Gammaproteobacteria P CorA-like Mg2+ transporter protein zntB GO:0000041,GO:0003674,GO:0005215,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0015562,GO:0016020,GO:0016021,GO:0022857,GO:0022883,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046583,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662 - ko:K16074 - - - - ko00000,ko02000 1.A.35.4 - - CorA k141_13490_2 1279017.AQYJ01000024_gene871 1.01e-108 322.0 COG1946@1|root,COG1946@2|Bacteria,1NAQM@1224|Proteobacteria,1S29R@1236|Gammaproteobacteria,46DI0@72275|Alteromonadaceae 1236|Gammaproteobacteria I Thioesterase-like superfamily - - - - - - - - - - - - 4HBT_3 k141_13490_3 1453501.JELR01000001_gene3131 3.51e-166 468.0 COG0413@1|root,COG0413@2|Bacteria,1MU3B@1224|Proteobacteria,1RM8D@1236|Gammaproteobacteria,464SP@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate panB - 2.1.2.11 ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R01226 RC00022,RC00200 ko00000,ko00001,ko00002,ko01000 - - - Pantoate_transf k141_445_1 218284.CCDN010000002_gene2115 1.77e-208 577.0 COG0115@1|root,COG0115@2|Bacteria,1TPY2@1239|Firmicutes,4HC7T@91061|Bacilli,1ZQE0@1386|Bacillus 91061|Bacilli E Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family ilvE - 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_4 k141_9853_2 279010.BL05128 2.75e-41 140.0 2DNPK@1|root,32YFU@2|Bacteria,1VFCK@1239|Firmicutes,4HQNX@91061|Bacilli,1ZK6M@1386|Bacillus 91061|Bacilli S Bacteriophage HK97-gp10, putative tail-component - - - - - - - - - - - - HK97-gp10_like k141_13491_1 218284.CCDN010000001_gene1019 4.94e-43 151.0 COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,4HA1P@91061|Bacilli,1ZC8I@1386|Bacillus 91061|Bacilli L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII dinB2 - - ko:K03502 - - - - ko00000,ko03400 - - - IMS,IMS_C,IMS_HHH k141_22980_1 1116375.VEJY3_04775 6.36e-126 362.0 COG0398@1|root,COG0398@2|Bacteria,1MVF3@1224|Proteobacteria,1SA94@1236|Gammaproteobacteria,1XTD5@135623|Vibrionales 135623|Vibrionales S SNARE associated Golgi protein - - - - - - - - - - - - SNARE_assoc k141_22980_2 223926.28806013 2.24e-54 171.0 2EPYS@1|root,33HJC@2|Bacteria,1QXDN@1224|Proteobacteria,1T397@1236|Gammaproteobacteria,1XYD4@135623|Vibrionales 135623|Vibrionales S Putative prokaryotic signal transducing protein - - - - - - - - - - - - DUF2007 k141_22980_3 223926.28806012 2.87e-168 472.0 COG0596@1|root,COG0596@2|Bacteria,1R53J@1224|Proteobacteria,1RXY0@1236|Gammaproteobacteria,1XV80@135623|Vibrionales 135623|Vibrionales S hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - - - - - - - - - - Abhydrolase_1 k141_24096_1 1131730.BAVI_00325 3.95e-79 242.0 COG2045@1|root,COG2045@2|Bacteria,1UZ7A@1239|Firmicutes,4HCE8@91061|Bacilli 91061|Bacilli H Belongs to the ComB family - - 3.1.3.71 ko:K05979 ko00680,ko01120,map00680,map01120 M00358 R05789 RC00428 ko00000,ko00001,ko00002,ko01000 - - - 2-ph_phosp k141_8679_2 1385513.N780_03435 1.09e-60 187.0 COG2151@1|root,COG2151@2|Bacteria,1V9YV@1239|Firmicutes,4HKC6@91061|Bacilli,2YAK4@289201|Pontibacillus 91061|Bacilli S DNA methyltransferase yitW - - - - - - - - - - - FeS_assembly_P k141_8679_3 866895.HBHAL_2284 1.96e-16 76.3 COG1073@1|root,COG1073@2|Bacteria,1TTC0@1239|Firmicutes,4HBCG@91061|Bacilli,3NENX@45667|Halobacillus 91061|Bacilli S Prolyl oligopeptidase family yitV - - ko:K06889 - - - - ko00000 - - - Abhydrolase_1,Hydrolase_4,Peptidase_S9 k141_21749_1 218284.CCDN010000001_gene253 1.56e-29 115.0 COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,4HAWB@91061|Bacilli,1ZAQK@1386|Bacillus 91061|Bacilli J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS - 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1 k141_12343_3 218284.CCDN010000005_gene3442 6.08e-66 201.0 COG1320@1|root,COG1320@2|Bacteria,1VABT@1239|Firmicutes,4HKX5@91061|Bacilli,1ZHVK@1386|Bacillus 91061|Bacilli P COG1320 Multisubunit Na H antiporter, MnhG subunit mrpG - - ko:K05571 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - iYO844.BSU31660 PhaG_MnhG_YufB k141_12343_4 218284.CCDN010000005_gene3441 2.36e-54 171.0 COG4876@1|root,COG4876@2|Bacteria,1V4YD@1239|Firmicutes,4HM8N@91061|Bacilli,1ZH18@1386|Bacillus 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2188) - - - - - - - - - - - - DUF2188 k141_28896_1 1453501.JELR01000002_gene797 2.11e-39 141.0 COG0617@1|root,COG0617@2|Bacteria,1MU2X@1224|Proteobacteria,1RPFJ@1236|Gammaproteobacteria,4641Q@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate cca GO:0003674,GO:0003824,GO:0004652,GO:0004810,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0070566,GO:0071704,GO:0090304,GO:1901360,GO:1990817 2.7.7.72 ko:K00974 ko03013,map03013 - R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016 - - - HD,PolyA_pol,PolyA_pol_RNAbd k141_28896_2 1042377.AFPJ01000043_gene943 2.76e-143 407.0 COG1028@1|root,COG1028@2|Bacteria,1MUUV@1224|Proteobacteria,1RMJU@1236|Gammaproteobacteria,466CG@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) ycdF - 1.5.1.33 ko:K03793 - - - - ko00000,ko01000 - - - adh_short_C2 k141_2747_1 218284.CCDN010000005_gene3403 9.2e-117 340.0 2B51H@1|root,31XUS@2|Bacteria,1V6KA@1239|Firmicutes,4HKBP@91061|Bacilli,1ZFY9@1386|Bacillus 91061|Bacilli S Sporulation protein YunB (Spo_YunB) yunB - - - - - - - - - - - Spore_YunB k141_1484_1 218284.CCDN010000001_gene1285 1.08e-86 258.0 COG0135@1|root,COG0135@2|Bacteria,1V6Y0@1239|Firmicutes,4HJ7Y@91061|Bacilli,1ZGH8@1386|Bacillus 91061|Bacilli E Belongs to the TrpF family trpF - 5.3.1.24 ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03509 RC00945 ko00000,ko00001,ko00002,ko01000 - - - PRAI k141_1484_2 218284.CCDN010000001_gene1286 5.25e-40 142.0 COG0133@1|root,COG0133@2|Bacteria,1TPI3@1239|Firmicutes,4H9WC@91061|Bacilli,1ZCBT@1386|Bacillus 91061|Bacilli E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine trpB GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20,5.3.1.24 ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722,R03509 RC00209,RC00210,RC00700,RC00701,RC00945,RC02868 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU22640 PALP k141_8680_1 1294265.JCM21738_4962 3.72e-139 405.0 COG0665@1|root,COG0723@1|root,COG0665@2|Bacteria,COG0723@2|Bacteria,1TR1R@1239|Firmicutes,4H9V8@91061|Bacilli,1ZC19@1386|Bacillus 91061|Bacilli CE COG0665 Glycine D-amino acid oxidases (deaminating) yhfW GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0044424,GO:0044464,GO:0055114 - - - - - - - - - - DAO,Rieske k141_9855_1 218284.CCDN010000007_gene3905 1.69e-92 280.0 COG0156@1|root,COG0156@2|Bacteria,1TPUX@1239|Firmicutes,4HAH3@91061|Bacilli,1ZAUZ@1386|Bacillus 91061|Bacilli H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide kbl GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29 ko:K00639 ko00260,map00260 - R00371 RC00004,RC00394 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 k141_24097_1 218284.CCDN010000011_gene4416 1.26e-86 266.0 COG0013@1|root,COG0013@2|Bacteria,1TSBZ@1239|Firmicutes,4HADV@91061|Bacilli,1ZDMJ@1386|Bacillus 91061|Bacilli J metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain alaS_2 - 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DHHA1,tRNA-synt_2c,tRNA_SAD k141_26676_1 441769.ABFU01000050_gene3968 6.72e-05 43.9 COG0754@1|root,COG0754@2|Bacteria,1UTUT@1239|Firmicutes,4HBAJ@91061|Bacilli,1ZB3R@1386|Bacillus 91061|Bacilli E Glutathionylspermidine synthase preATP-grasp - - - - - - - - - - - - GSP_synth k141_26676_2 1243664.CAVL020000058_gene4484 2.41e-21 89.4 2E6P8@1|root,3319M@2|Bacteria,1VIXA@1239|Firmicutes,4HP8N@91061|Bacilli,1ZJ65@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_26676_3 218284.CCDN010000007_gene3820 8.08e-78 234.0 2BEBR@1|root,3282S@2|Bacteria,1V6PA@1239|Firmicutes,4HM09@91061|Bacilli,1ZQIB@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_37123_1 501479.ACNW01000055_gene4126 2.67e-113 338.0 COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,2TRFV@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Belongs to the pyruvate kinase family pyk - 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - PK,PK_C k141_13492_1 935836.JAEL01000002_gene531 3.55e-148 421.0 COG0020@1|root,COG0020@2|Bacteria,1TQTS@1239|Firmicutes,4HA37@91061|Bacilli,1ZC2T@1386|Bacillus 91061|Bacilli I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids uppS GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 ko:K00806 ko00900,ko01110,map00900,map01110 - R06447 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 - - - Prenyltransf k141_5100_1 223926.28805053 2.19e-103 301.0 COG1522@1|root,COG1522@2|Bacteria,1MWPX@1224|Proteobacteria,1RRPA@1236|Gammaproteobacteria,1XSDD@135623|Vibrionales 135623|Vibrionales K COG1522 Transcriptional regulators asnC - - ko:K03718 - - - - ko00000,ko03000 - - - AsnC_trans_reg,HTH_AsnC-type k141_19344_2 218284.CCDN010000001_gene1934 3.35e-64 199.0 COG1558@1|root,COG1558@2|Bacteria,1V6NB@1239|Firmicutes,4HH4W@91061|Bacilli,1ZGA0@1386|Bacillus 91061|Bacilli N Belongs to the flagella basal body rod proteins family flgC GO:0001539,GO:0005575,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009424,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588 - ko:K02388 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C k141_20484_1 218284.CCDN010000006_gene3742 2.83e-178 498.0 COG0395@1|root,COG0395@2|Bacteria,1TRCP@1239|Firmicutes,4HBKE@91061|Bacilli,1ZEM8@1386|Bacillus 91061|Bacilli G Binding-protein-dependent transport system inner membrane component lacG - - ko:K02026 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - BPD_transp_1 k141_20484_2 218284.CCDN010000006_gene3743 5.9e-182 509.0 COG1175@1|root,COG1175@2|Bacteria,1TPMR@1239|Firmicutes,4HA5B@91061|Bacilli,1ZRMB@1386|Bacillus 91061|Bacilli G Binding-protein-dependent transport system inner membrane component lacF3 - - ko:K02025,ko:K10241 ko02010,map02010 M00206,M00207 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.23 - - BPD_transp_1 k141_12345_1 698769.JFBD01000072_gene1842 2.11e-67 221.0 COG0591@1|root,COG0591@2|Bacteria,1U2RF@1239|Firmicutes,4IJK4@91061|Bacilli,4C68Z@84406|Virgibacillus 91061|Bacilli E Sodium:solute symporter family - - - ko:K03307 - - - - ko00000 2.A.21 - - SSF k141_25314_1 1453501.JELR01000002_gene868 2.63e-12 66.2 COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,1RYP9@1236|Gammaproteobacteria,465IE@72275|Alteromonadaceae 1236|Gammaproteobacteria E ERAP1-like C-terminal domain - - 3.4.11.14 ko:K01263 - - - - ko00000,ko01000 - - - ERAP1_C,Peptidase_M1 k141_25314_2 1453501.JELR01000002_gene869 1.85e-49 170.0 COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,1S13F@1236|Gammaproteobacteria,466IW@72275|Alteromonadaceae 1236|Gammaproteobacteria S Sulfotransferase domain - - - - - - - - - - - - Sulfotransfer_3,TPR_19,TPR_8 k141_24098_1 1294265.JCM21738_4730 1.47e-14 67.4 COG1925@1|root,COG1925@2|Bacteria,1VA0R@1239|Firmicutes,4HKGA@91061|Bacilli,1ZHX7@1386|Bacillus 91061|Bacilli G phosphocarrier protein HPr ptsH GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0043610,GO:0044424,GO:0044464,GO:0050789,GO:0065007 - ko:K11189 - - - - ko00000,ko02000 4.A.2.1 - - PTS-HPr k141_24098_2 1294265.JCM21738_4731 7.15e-125 364.0 COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,4H9VD@91061|Bacilli,1ZAU2@1386|Bacillus 91061|Bacilli G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) ptsI GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0051179,GO:0051234,GO:0071702 2.7.3.9 ko:K08483 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 8.A.7 - - PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C k141_35946_2 446465.Bfae_18180 9.85e-22 95.5 COG0406@1|root,COG0406@2|Bacteria,2GJYU@201174|Actinobacteria,4FCNZ@85020|Dermabacteraceae 201174|Actinobacteria G Phosphoglycerate mutase family gpmB GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0044237 3.1.3.85,5.4.2.11 ko:K01834,ko:K22306 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - His_Phos_1 k141_32355_1 926569.ANT_17320 8.38e-36 130.0 29XJU@1|root,30JAW@2|Bacteria,2G9DS@200795|Chloroflexi 200795|Chloroflexi - - - - - - - - - - - - - - - k141_33657_1 1224136.AMFN01000002_gene1055 5.63e-09 65.1 COG3210@1|root,COG3210@2|Bacteria,1MX2K@1224|Proteobacteria,1RNRK@1236|Gammaproteobacteria 1236|Gammaproteobacteria U Large exoproteins involved in heme utilization or adhesion fhaB - - ko:K15125 ko05133,map05133 - - - ko00000,ko00001,ko00536 - - - ESPR,Fil_haemagg,Fil_haemagg_2,Haemagg_act,PT-VENN k141_26703_1 1227360.C176_04708 9.13e-165 472.0 COG0402@1|root,COG0402@2|Bacteria,1TS92@1239|Firmicutes,4HCME@91061|Bacilli,26DAT@186818|Planococcaceae 91061|Bacilli F Amidohydrolase family - - - - - - - - - - - - Amidohydro_3 k141_33658_1 406124.ACPC01000009_gene1481 4.62e-69 233.0 COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,4HAFP@91061|Bacilli,1ZBJ3@1386|Bacillus 91061|Bacilli V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran k141_4024_1 218284.CCDN010000001_gene1516 1.38e-197 558.0 COG1292@1|root,COG1292@2|Bacteria,1TRS6@1239|Firmicutes,4HA7U@91061|Bacilli,1ZBRN@1386|Bacillus 91061|Bacilli M Belongs to the BCCT transporter (TC 2.A.15) family opuD GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0016020,GO:0031460,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0072337 - ko:K05020 - - - - ko00000,ko02000 2.A.15.1.1,2.A.15.1.11 - iYO844.BSU30070 BCCT k141_11077_1 1042377.AFPJ01000030_gene442 1.94e-66 222.0 COG3240@1|root,COG3240@2|Bacteria,1RCCU@1224|Proteobacteria,1S2GX@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Phospholipase lecithinase hemolysin estA GO:0003674,GO:0003824,GO:0016289,GO:0016290,GO:0016787,GO:0016788,GO:0016790,GO:0047617,GO:0052689 - ko:K12686 - - - - ko00000,ko02000,ko02044 1.B.12.8 - - Autotransporter,Lipase_GDSL k141_31273_1 1192034.CAP_0448 2.41e-50 181.0 COG0457@1|root,COG0515@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,42NXT@68525|delta/epsilon subdivisions,2WIZ3@28221|Deltaproteobacteria,2YU18@29|Myxococcales 28221|Deltaproteobacteria KLT Adenylyl- / guanylyl cyclase, catalytic domain - - - - - - - - - - - - AAA_16,Guanylate_cyc,Pkinase k141_12363_2 946483.Cenrod_1887 2.43e-11 66.2 COG3829@1|root,COG5001@1|root,COG3829@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria 28216|Betaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - EAL,GAF,GGDEF,HAMP,PAS_9,dCache_3 k141_33659_1 1279017.AQYJ01000023_gene3087 7.04e-64 216.0 COG3563@1|root,COG3563@2|Bacteria,1MW0T@1224|Proteobacteria,1RPMS@1236|Gammaproteobacteria,469Q2@72275|Alteromonadaceae 1236|Gammaproteobacteria M Capsule polysaccharide biosynthesis protein - - - ko:K07266 - - - - ko00000 - - - Capsule_synth k141_11078_1 218284.CCDN010000008_gene4266 1.68e-119 352.0 COG0301@1|root,COG0301@2|Bacteria,1TPNW@1239|Firmicutes,4HAV9@91061|Bacilli,1ZBZY@1386|Bacillus 91061|Bacilli H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS thiI - 2.8.1.4 ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07461 - ko00000,ko00001,ko01000,ko03016 - - - THUMP,ThiI k141_28916_1 42565.FP66_01415 1.31e-88 273.0 COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,1RMN6@1236|Gammaproteobacteria,1XJ03@135619|Oceanospirillales 135619|Oceanospirillales P Trk system potassium uptake protein - - - ko:K03498 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkH k141_8718_1 1279017.AQYJ01000029_gene3369 1.08e-92 276.0 COG3751@1|root,COG3751@2|Bacteria,1R4BC@1224|Proteobacteria 1224|Proteobacteria O 2OG-Fe(II) oxygenase superfamily - - - - - - - - - - - - 2OG-FeII_Oxy_3 k141_7453_2 1453501.JELR01000002_gene1325 2.05e-60 191.0 COG0848@1|root,COG0848@2|Bacteria,1RHI8@1224|Proteobacteria,1S6FK@1236|Gammaproteobacteria,467HF@72275|Alteromonadaceae 1236|Gammaproteobacteria U COG0848 Biopolymer transport protein - - - - - - - - - - - - ExbD k141_23017_1 1453501.JELR01000001_gene2939 5.66e-30 114.0 COG0500@1|root,COG2226@2|Bacteria,1MXDY@1224|Proteobacteria,1RMU7@1236|Gammaproteobacteria,466NC@72275|Alteromonadaceae 1236|Gammaproteobacteria Q COG0500 SAM-dependent methyltransferases rrmA GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008270,GO:0008649,GO:0008757,GO:0008989,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.187 ko:K00563 - - R07233 RC00003 ko00000,ko01000,ko03009 - - - Methyltransf_11,Methyltransf_25,Methyltransf_31 k141_15822_2 218284.CCDN010000007_gene3944 2.14e-71 219.0 COG1994@1|root,COG1994@2|Bacteria,1V6D4@1239|Firmicutes,4H9SF@91061|Bacilli,1ZCSE@1386|Bacillus 91061|Bacilli S Peptidase M50 ywhC - - - - - - - - - - - Peptidase_M50 k141_21774_1 1453501.JELR01000005_gene1584 1.73e-116 343.0 COG4977@1|root,COG4977@2|Bacteria,1R01Y@1224|Proteobacteria,1T4DW@1236|Gammaproteobacteria,46DE7@72275|Alteromonadaceae 1236|Gammaproteobacteria K helix_turn_helix, arabinose operon control protein - - - - - - - - - - - - HTH_18 k141_34810_1 218284.CCDN010000002_gene2395 4.71e-112 332.0 2DBJR@1|root,2Z9N7@2|Bacteria,1TRSN@1239|Firmicutes,4HCDI@91061|Bacilli,1ZN92@1386|Bacillus 91061|Bacilli S Spore germination B3/ GerAC like, C-terminal - - - - - - - - - - - - Spore_GerAC k141_34810_2 218284.CCDN010000002_gene2394 3.85e-178 502.0 COG0814@1|root,COG0814@2|Bacteria,1UIWV@1239|Firmicutes,4ISV2@91061|Bacilli 91061|Bacilli E Spore germination protein - - - - - - - - - - - - Spore_permease k141_25339_2 1042377.AFPJ01000009_gene278 8.08e-46 152.0 2DP6U@1|root,330T2@2|Bacteria,1N7R9@1224|Proteobacteria,1SDI8@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - Gly-zipper_Omp,Gly-zipper_OmpA,Gly-zipper_YMGG k141_33660_1 1254432.SCE1572_33175 5.97e-80 258.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42M2A@68525|delta/epsilon subdivisions,2WJ41@28221|Deltaproteobacteria,2YUJJ@29|Myxococcales 28221|Deltaproteobacteria S ABC transporter, ATP-binding protein ybiT - - - - - - - - - - - ABC_tran,ABC_tran_Xtn k141_468_1 926550.CLDAP_19400 7.63e-41 149.0 COG0577@1|root,COG0577@2|Bacteria,2G65B@200795|Chloroflexi 200795|Chloroflexi V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD k141_4026_2 218284.CCDN010000005_gene3263 4.89e-150 426.0 COG1073@1|root,COG1073@2|Bacteria,1TTC0@1239|Firmicutes,4HBCG@91061|Bacilli,1ZBIJ@1386|Bacillus 91061|Bacilli S COG1073 Hydrolases of the alpha beta superfamily yitV - - ko:K06889 - - - - ko00000 - - - Abhydrolase_1,Hydrolase_4,Peptidase_S9 k141_14593_1 218284.CCDN010000003_gene3016 9.09e-252 697.0 COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,4H9X4@91061|Bacilli,1ZAVI@1386|Bacillus 91061|Bacilli J Belongs to the class-II aminoacyl-tRNA synthetase family lysS - 6.1.1.6 ko:K04567 ko00970,map00970 M00359,M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2,tRNA_anti-codon k141_37137_1 218284.CCDN010000002_gene2229 1.76e-71 237.0 COG5000@1|root,COG5002@1|root,COG5000@2|Bacteria,COG5002@2|Bacteria,1VS6X@1239|Firmicutes,4HV7W@91061|Bacilli,1ZS6R@1386|Bacillus 91061|Bacilli T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,dCache_1 k141_9894_2 398767.Glov_1877 8.38e-15 78.6 COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria 1224|Proteobacteria M peptidase - - - - - - - - - - - - DUF4124,Peptidase_M23,Peptidase_M56,Rod-binding k141_32357_1 218284.CCDN010000001_gene1944 5e-142 405.0 COG0039@1|root,COG0039@2|Bacteria,1TPSY@1239|Firmicutes,4HB0Z@91061|Bacilli,1ZD2C@1386|Bacillus 91061|Bacilli C Belongs to the LDH MDH superfamily. LDH family ldh GO:0003674,GO:0003824,GO:0004457,GO:0004459,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 - R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 - - - Ldh_1_C,Ldh_1_N k141_8720_1 1499680.CCFE01000011_gene516 4.29e-38 129.0 COG3924@1|root,COG3924@2|Bacteria,1VAE9@1239|Firmicutes,4HKFU@91061|Bacilli,1ZICT@1386|Bacillus 91061|Bacilli S Sodium pantothenate symporter - - - - - - - - - - - - DUF997 k141_25340_1 218284.CCDN010000002_gene2011 6.47e-59 186.0 COG5506@1|root,COG5506@2|Bacteria,1VFCV@1239|Firmicutes,4HNNE@91061|Bacilli,1ZI9H@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF1694) XK27_05190 - - - - - - - - - - - DUF1694 k141_13527_1 1042377.AFPJ01000012_gene1380 3.6e-89 266.0 2AEBT@1|root,31468@2|Bacteria,1RC39@1224|Proteobacteria,1S7QQ@1236|Gammaproteobacteria,468QT@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_28917_1 218284.CCDN010000005_gene3331 5.05e-118 350.0 COG0362@1|root,COG0362@2|Bacteria,1TP4I@1239|Firmicutes,4H9NC@91061|Bacilli,1ZC6M@1386|Bacillus 91061|Bacilli G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH gnd - 1.1.1.343,1.1.1.44 ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 M00004,M00006 R01528,R10221 RC00001,RC00539 ko00000,ko00001,ko00002,ko01000 - - - 6PGD,NAD_binding_2 k141_11080_1 406124.ACPC01000046_gene2352 2.31e-150 440.0 COG3119@1|root,COG3119@2|Bacteria,1UDRD@1239|Firmicutes,4HD9J@91061|Bacilli,1ZCSX@1386|Bacillus 91061|Bacilli P Protein of unknown function (DUF229) - - - - - - - - - - - - DUF4976,Sulfatase k141_7454_1 218284.CCDN010000001_gene1273 1.53e-113 344.0 COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,1TSAC@1239|Firmicutes,4HAJG@91061|Bacilli,1ZB2G@1386|Bacillus 91061|Bacilli L ATP-dependent DNA ligase ligD - 6.5.1.1 ko:K01971 ko03450,map03450 - R00381 RC00005 ko00000,ko00001,ko01000,ko03400 - - - DNA_ligase_A_M k141_26704_1 1042377.AFPJ01000037_gene3018 0.0 1140.0 COG0326@1|root,COG0326@2|Bacteria,1MUUE@1224|Proteobacteria,1RNWD@1236|Gammaproteobacteria,4647F@72275|Alteromonadaceae 1236|Gammaproteobacteria O Molecular chaperone. Has ATPase activity htpG GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0006974,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0042623,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716 - ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 - - - ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 - - - HATPase_c,HATPase_c_3,HSP90 k141_24112_1 218284.CCDN010000006_gene3544 9.17e-115 330.0 COG0655@1|root,COG0655@2|Bacteria,1V1DK@1239|Firmicutes,4HG41@91061|Bacilli,1ZFK5@1386|Bacillus 91061|Bacilli S NAD(P)H-dependent ywqN - - - - - - - - - - - FMN_red,Flavodoxin_2 k141_24112_2 1174504.AJTN02000054_gene1704 9.79e-29 106.0 2E3GS@1|root,32YFG@2|Bacteria,1VGU9@1239|Firmicutes,4HNWB@91061|Bacilli,1ZHW7@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_19365_1 223926.28805222 1.3e-69 211.0 COG3232@1|root,COG3232@2|Bacteria,1N7P5@1224|Proteobacteria,1S5D7@1236|Gammaproteobacteria,1XXDP@135623|Vibrionales 135623|Vibrionales G 5-carboxymethyl-2-hydroxymuconate isomerase hpcD - 5.3.3.10 ko:K01826 ko00350,ko01120,ko01220,map00350,map01120,map01220 M00533 R04379,R04482 RC01141,RC01162 ko00000,ko00001,ko00002,ko01000 - - - CHMI k141_9895_1 1089552.KI911559_gene3197 2.92e-49 171.0 COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,2TSBK@28211|Alphaproteobacteria,2JQ4Y@204441|Rhodospirillales 204441|Rhodospirillales J Responsible for synthesis of pseudouridine from uracil rluD - 5.4.99.23 ko:K06180 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 k141_12364_1 1453501.JELR01000001_gene2506 1.91e-107 317.0 28M8G@1|root,2ZAMM@2|Bacteria,1MVBT@1224|Proteobacteria,1RMAM@1236|Gammaproteobacteria,467EP@72275|Alteromonadaceae 1236|Gammaproteobacteria S RES - - - - - - - - - - - - RES k141_12364_2 1453501.JELR01000001_gene2507 3.99e-53 169.0 COG5642@1|root,COG5642@2|Bacteria,1N2DF@1224|Proteobacteria,1S93Q@1236|Gammaproteobacteria,4689N@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF2384) - - - - - - - - - - - - DUF2384,HTH_3 k141_34812_1 318586.Pden_3079 3.56e-72 218.0 COG1943@1|root,COG1943@2|Bacteria,1RF1K@1224|Proteobacteria,2U886@28211|Alphaproteobacteria,2PY7E@265|Paracoccus 28211|Alphaproteobacteria L Transposase IS200 like - - - ko:K07491 - - - - ko00000 - - - Y1_Tnp k141_4028_1 218284.CCDN010000002_gene2067 7.54e-164 463.0 COG0055@1|root,COG0055@2|Bacteria,1UATS@1239|Firmicutes,4HBRA@91061|Bacilli,1ZDEJ@1386|Bacillus 91061|Bacilli C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits - - 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - HTH_26 k141_8721_1 218284.CCDN010000008_gene4251 4.82e-132 394.0 COG2199@1|root,COG2203@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,1TQ2X@1239|Firmicutes,4HA6T@91061|Bacilli,1ZCE7@1386|Bacillus 91061|Bacilli T COG2199 FOG GGDEF domain ytrP - - - - - - - - - - - GAF_2,GAF_3,GGDEF k141_13529_1 933115.GPDM_04494 2.11e-08 54.3 COG0775@1|root,COG0775@2|Bacteria,1TSB7@1239|Firmicutes,4HDEM@91061|Bacilli,26EHK@186818|Planococcaceae 91061|Bacilli F Phosphorylase superfamily - - 3.2.2.9 ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 M00034,M00609 R00194,R01401 RC00063,RC00318 ko00000,ko00001,ko00002,ko01000 - - - Cu_amine_oxidN1,PNP_UDP_1 k141_13529_2 218284.CCDN010000002_gene2762 3.22e-69 215.0 COG0300@1|root,COG0300@2|Bacteria,1TPN1@1239|Firmicutes,4HBGE@91061|Bacilli,1ZDT2@1386|Bacillus 91061|Bacilli S Enoyl-(Acyl carrier protein) reductase - - - - - - - - - - - - adh_short k141_27607_2 1294265.JCM21738_1335 4.31e-89 262.0 COG2111@1|root,COG2111@2|Bacteria,1V3VF@1239|Firmicutes,4HHAN@91061|Bacilli,1ZHC0@1386|Bacillus 91061|Bacilli P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali mrpB - - ko:K05566 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - MnhB k141_27607_3 1294265.JCM21738_1334 2e-102 310.0 COG1009@1|root,COG2111@1|root,COG1009@2|Bacteria,COG2111@2|Bacteria,1TQW4@1239|Firmicutes,4H9YR@91061|Bacilli,1ZAZ0@1386|Bacillus 91061|Bacilli CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit mrpA GO:0003674,GO:0005215,GO:0005451,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015491,GO:0015672,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0035725,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0098655,GO:0098660,GO:0098662,GO:0099516,GO:1902600 - ko:K05565 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - DUF4040,Proton_antipo_M,Proton_antipo_N k141_7474_2 218284.CCDN010000001_gene1013 4.57e-29 110.0 COG0345@1|root,COG0345@2|Bacteria,1TP1E@1239|Firmicutes,4H9RV@91061|Bacilli,1ZCWZ@1386|Bacillus 91061|Bacilli E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline proC - 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 - - - F420_oxidored,P5CR_dimer k141_18272_1 218284.CCDN010000001_gene1175 3.07e-90 271.0 COG0258@1|root,COG0258@2|Bacteria,1TQ05@1239|Firmicutes,4H9UW@91061|Bacilli,1ZB2Z@1386|Bacillus 91061|Bacilli L 5'3' exonuclease ypcP - - - - - - - - - - - 5_3_exonuc,5_3_exonuc_N k141_8747_1 1042377.AFPJ01000021_gene2118 1.42e-170 492.0 COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,1RPI1@1236|Gammaproteobacteria,466VC@72275|Alteromonadaceae 1236|Gammaproteobacteria M Biotin-lipoyl like - - - ko:K03585 ko01501,ko01503,map01501,map01503 M00646,M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,8.A.1.6 - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 k141_8747_2 1042377.AFPJ01000021_gene2116 1.64e-275 762.0 COG0531@1|root,COG0531@2|Bacteria,1MUA2@1224|Proteobacteria,1RNND@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Arginine ornithine antiporter arcD_2 - - ko:K03757,ko:K03758 - - - - ko00000,ko02000 2.A.3.2 - - AA_permease_2 k141_8747_3 765911.Thivi_1392 1.17e-243 676.0 COG2235@1|root,COG2235@2|Bacteria,1NCGV@1224|Proteobacteria,1RM99@1236|Gammaproteobacteria,1WZMQ@135613|Chromatiales 135613|Chromatiales E Arginine deiminase arcA - 3.5.3.6 ko:K01478 ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130 - R00552 RC00177 ko00000,ko00001,ko01000 - - - Amidinotransf k141_8747_4 1279017.AQYJ01000021_gene2825 1.54e-115 332.0 COG1051@1|root,COG1051@2|Bacteria,1REBW@1224|Proteobacteria,1S3XB@1236|Gammaproteobacteria,466XR@72275|Alteromonadaceae 1236|Gammaproteobacteria F COG1051 ADP-ribose pyrophosphatase - - - - - - - - - - - - NUDIX,Nudix_N_2 k141_8747_5 1042377.AFPJ01000014_gene1632 1.89e-134 389.0 COG4099@1|root,COG4099@2|Bacteria,1RHBS@1224|Proteobacteria,1T15X@1236|Gammaproteobacteria,46904@72275|Alteromonadaceae 1236|Gammaproteobacteria S Prolyl oligopeptidase family - - - - - - - - - - - - Esterase,Peptidase_S9 k141_8747_6 1453501.JELR01000001_gene2932 1.12e-63 195.0 COG3323@1|root,COG3323@2|Bacteria,1MZF5@1224|Proteobacteria,1S8WV@1236|Gammaproteobacteria,467S4@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria - - - ko:K11022 ko05134,map05134 - - - ko00000,ko00001,ko02042 - - - - k141_8747_7 1453501.JELR01000001_gene2933 2.51e-122 357.0 COG3118@1|root,COG3118@2|Bacteria,1MV0R@1224|Proteobacteria,1RMSQ@1236|Gammaproteobacteria,4641J@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG3118 Thioredoxin domain-containing protein ybbN GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0008150,GO:0008152,GO:0009987,GO:0015035,GO:0015036,GO:0016491,GO:0016667,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0061077 - ko:K03671,ko:K05838 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - TPR_19,TPR_20,Thioredoxin k141_19402_1 330214.NIDE0845 3.06e-110 330.0 COG0499@1|root,COG0499@2|Bacteria,3J0AH@40117|Nitrospirae 40117|Nitrospirae H May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine ahcY - 3.3.1.1 ko:K01251 ko00270,ko01100,map00270,map01100 M00035 R00192,R04936 RC00056,RC00069,RC01161,RC01243 ko00000,ko00001,ko00002,ko01000,ko01009,ko04147 - - - AdoHcyase,AdoHcyase_NAD k141_20534_1 1304275.C41B8_17983 3.57e-79 248.0 COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,1RPHI@1236|Gammaproteobacteria 1236|Gammaproteobacteria J histidyl-tRNA synthetase hisS GO:0003674,GO:0003824,GO:0004812,GO:0004821,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006427,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iE2348C_1286.E2348C_2797,iECNA114_1301.ECNA114_2592,iECSF_1327.ECSF_2358 HGTP_anticodon,tRNA-synt_His k141_13568_2 224308.BSU12560 2.97e-13 71.6 COG1595@1|root,COG1595@2|Bacteria,1VAEY@1239|Firmicutes,4HMVP@91061|Bacilli,1ZJ9T@1386|Bacillus 91061|Bacilli K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog xpf - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r4_2 k141_21791_1 861299.J421_3473 6.46e-25 102.0 COG0599@1|root,COG0599@2|Bacteria,1ZTPF@142182|Gemmatimonadetes 142182|Gemmatimonadetes S Carboxymuconolactone decarboxylase family - - 4.1.1.44 ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 - R03470 RC00938 ko00000,ko00001,ko01000 - - - CMD k141_21791_2 871968.DESME_07570 3.94e-20 84.3 COG0824@1|root,COG0824@2|Bacteria,1VAGM@1239|Firmicutes,24NBX@186801|Clostridia,262HZ@186807|Peptococcaceae 186801|Clostridia S TIGRFAM acyl-CoA thioester hydrolase, YbgC YbaW family FcbC - - ko:K07107 - - - - ko00000,ko01000 - - - 4HBT,4HBT_2 k141_33699_1 218284.CCDN010000004_gene3069 4.15e-146 422.0 COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,4H9TI@91061|Bacilli,1ZBG7@1386|Bacillus 91061|Bacilli I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol cls GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0032048,GO:0032049,GO:0032502,GO:0043934,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 - ko:K06131 ko00564,ko01100,map00564,map01100 - R07390 RC00017 ko00000,ko00001,ko01000 - - - PLDc_2,PLDc_N k141_37171_1 1129794.C427_3176 1.18e-32 129.0 COG1020@1|root,COG1020@2|Bacteria,1N7HY@1224|Proteobacteria,1RQJX@1236|Gammaproteobacteria,464B6@72275|Alteromonadaceae 1236|Gammaproteobacteria Q COG1020 Non-ribosomal peptide synthetase modules and related proteins - - - - - - - - - - - - DUF1298,WES_acyltransf k141_35962_1 1232683.ADIMK_1378 2.28e-39 132.0 COG2963@1|root,COG2963@2|Bacteria,1N3E0@1224|Proteobacteria,1S9T7@1236|Gammaproteobacteria,46847@72275|Alteromonadaceae 1236|Gammaproteobacteria L Helix-turn-helix domain - - - ko:K07483 - - - - ko00000 - - - HTH_Tnp_1 k141_35962_2 1122197.ATWI01000014_gene4 1.89e-54 179.0 COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,1RR4F@1236|Gammaproteobacteria,465JZ@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG2801 Transposase and inactivated derivatives - - - ko:K07497 - - - - ko00000 - - - HTH_21,rve k141_25366_1 1196031.ALEG01000039_gene1585 2.12e-47 161.0 COG0540@1|root,COG0540@2|Bacteria,1TQ96@1239|Firmicutes,4H9M6@91061|Bacilli,1ZBHG@1386|Bacillus 91061|Bacilli F Belongs to the ATCase OTCase family pyrB GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU15490 OTCace,OTCace_N k141_25366_2 935837.JAEK01000005_gene4551 1.63e-103 313.0 COG0044@1|root,COG0044@2|Bacteria,1TPQM@1239|Firmicutes,4HA90@91061|Bacilli,1ZAS7@1386|Bacillus 91061|Bacilli F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily pyrC GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 k141_17025_1 1461580.CCAS010000001_gene162 2.97e-18 86.3 COG1921@1|root,COG1921@2|Bacteria,1TQT8@1239|Firmicutes,4HAAC@91061|Bacilli,1ZCFY@1386|Bacillus 91061|Bacilli E Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis selA - 2.9.1.1 ko:K01042 ko00450,ko00970,map00450,map00970 - R08219 RC01246 ko00000,ko00001,ko01000 - - - Se-cys_synth_N,SelA k141_30006_1 1116375.VEJY3_19256 1.96e-97 295.0 COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,1RMR6@1236|Gammaproteobacteria,1XU3G@135623|Vibrionales 135623|Vibrionales Q COG4664 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - - - - - - - - - - DctM k141_30006_2 675816.VIA_001712 5.37e-41 136.0 2CJAG@1|root,32S9M@2|Bacteria,1N4PM@1224|Proteobacteria,1SAGF@1236|Gammaproteobacteria,1XYEJ@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF2999) - - - - - - - - - - - - DUF2999 k141_8748_1 1220589.CD32_01175 7.1e-14 71.2 2EGZP@1|root,33ART@2|Bacteria,1VKPB@1239|Firmicutes,4HR69@91061|Bacilli 91061|Bacilli S YopX protein - - - - - - - - - - - - YopX k141_33700_1 1379698.RBG1_1C00001G1125 7.75e-73 228.0 COG1692@1|root,COG1692@2|Bacteria,2NNW9@2323|unclassified Bacteria 2|Bacteria S YmdB-like protein ymdB GO:0003674,GO:0003824,GO:0004112,GO:0004113,GO:0008081,GO:0016787,GO:0016788,GO:0042578 - ko:K02029,ko:K02030,ko:K09769 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - YmdB k141_9932_1 218284.CCDN010000003_gene3005 1.55e-152 430.0 COG1521@1|root,COG1521@2|Bacteria,1TR0X@1239|Firmicutes,4H9QA@91061|Bacilli,1ZBQ0@1386|Bacillus 91061|Bacilli F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis coaX - 2.7.1.33 ko:K03525 ko00770,ko01100,map00770,map01100 M00120 R02971,R03018,R04391 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Pan_kinase k141_9932_2 218284.CCDN010000003_gene3006 2.32e-190 531.0 COG1281@1|root,COG1281@2|Bacteria,1TRCH@1239|Firmicutes,4HAFR@91061|Bacilli,1ZBFC@1386|Bacillus 91061|Bacilli O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress hslO - - ko:K04083 - - - - ko00000,ko03110 - - - HSP33 k141_12390_1 1454004.AW11_03084 1.26e-40 149.0 COG0760@1|root,COG0760@2|Bacteria,1R4ZR@1224|Proteobacteria,2W0N2@28216|Betaproteobacteria 28216|Betaproteobacteria O PPIC-type PPIASE domain - - - - - - - - - - - - Rotamase_2 k141_12390_2 1286632.P278_31300 1.05e-115 350.0 28HMZ@1|root,2Z7WD@2|Bacteria,4P095@976|Bacteroidetes 976|Bacteroidetes S Protein of unknown function (DUF3604) - - - - - - - - - - - - DUF3604 k141_32372_1 218284.CCDN010000001_gene300 2.19e-142 412.0 COG2508@1|root,COG2508@2|Bacteria,1TRRH@1239|Firmicutes,4HDGP@91061|Bacilli,1ZB6S@1386|Bacillus 91061|Bacilli QT Transcriptional regulator yukF GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032502,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043934,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - - - - - - - - - - CodY,HTH_30 k141_20535_1 1219065.VPR01S_20_00190 9.26e-54 183.0 COG0582@1|root,COG0582@2|Bacteria,1MX7E@1224|Proteobacteria,1RNX5@1236|Gammaproteobacteria,1XV8P@135623|Vibrionales 135623|Vibrionales L Bacteriophage lambda integrase, Arm DNA-binding domain - - - - - - - - - - - - Arm-DNA-bind_1,Phage_integrase k141_28927_1 1280001.BAOA01000021_gene729 1.36e-142 420.0 COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,1RNQ2@1236|Gammaproteobacteria,1XUT0@135623|Vibrionales 135623|Vibrionales GM nucleoside-diphosphate sugar epimerases - - - - - - - - - - - - CoA_binding_3,Polysacc_synt_2 k141_23043_2 1042377.AFPJ01000051_gene98 1.09e-117 354.0 COG0668@1|root,COG0668@2|Bacteria,1MY0I@1224|Proteobacteria,1RQKY@1236|Gammaproteobacteria,46A6M@72275|Alteromonadaceae 1236|Gammaproteobacteria M Mechanosensitive ion channel ybiO GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K22044 - - - - ko00000,ko02000 1.A.23.3 - - MS_channel k141_17026_1 1131730.BAVI_01390 7.3e-62 204.0 COG4191@1|root,COG4191@2|Bacteria,1UZ9W@1239|Firmicutes,4HDK2@91061|Bacilli,1ZD85@1386|Bacillus 91061|Bacilli T Histidine kinase kinB3 - 2.7.13.3 ko:K07697 ko02020,map02020 M00485 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - 5TM-5TMR_LYT,HATPase_c,HisKA k141_19404_2 333138.LQ50_12270 4.74e-16 75.1 COG0241@1|root,COG0241@2|Bacteria,1V6XD@1239|Firmicutes,4HDMZ@91061|Bacilli,1ZCJU@1386|Bacillus 91061|Bacilli E D,D-heptose 1,7-bisphosphate phosphatase - - 3.1.3.82,3.1.3.83 ko:K03273 ko00540,ko01100,map00540,map01100 M00064 R05647,R09771 RC00017 ko00000,ko00001,ko00002,ko01000,ko01005 - - - HAD_2,Hydrolase_like,PNK3P k141_7476_1 42565.FP66_14005 1.76e-156 446.0 COG1215@1|root,COG1215@2|Bacteria,1MWH9@1224|Proteobacteria,1RPTN@1236|Gammaproteobacteria,1XHKE@135619|Oceanospirillales 135619|Oceanospirillales M Glycosyl transferase - - 2.4.1.266 ko:K13693 - - - - ko00000,ko01000,ko01003 - GT81 - - k141_21793_1 720554.Clocl_2119 8.23e-15 79.7 COG0358@1|root,COG0358@2|Bacteria,1TQ0X@1239|Firmicutes,2480W@186801|Clostridia,3WGFW@541000|Ruminococcaceae 186801|Clostridia L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG - - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2 k141_33701_1 1294265.JCM21738_3771 1.86e-233 654.0 COG2414@1|root,COG2414@2|Bacteria,1TPT9@1239|Firmicutes,4HFIP@91061|Bacilli,1ZD3I@1386|Bacillus 91061|Bacilli C COG2414 Aldehyde ferredoxin oxidoreductase - - 1.2.7.5 ko:K03738 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 M00309 R08571 RC00242 ko00000,ko00001,ko00002,ko01000 - - - AFOR_C,AFOR_N k141_8750_1 1384049.CD29_03085 7.25e-106 315.0 COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,4I4DI@91061|Bacilli,3IZPG@400634|Lysinibacillus 91061|Bacilli L Transposase, Mutator family - - - - - - - - - - - - Transposase_mut k141_6438_2 1294265.JCM21738_504 2.45e-138 393.0 COG0702@1|root,COG0702@2|Bacteria,1V112@1239|Firmicutes,4HEVN@91061|Bacilli,1ZG8I@1386|Bacillus 91061|Bacilli GM NAD(P)H-binding M1-688 - - - - - - - - - - - Epimerase,HIM1,NAD_binding_10 k141_37174_1 218284.CCDN010000001_gene1269 1.15e-159 456.0 COG2252@1|root,COG2252@2|Bacteria,1TQC6@1239|Firmicutes,4HBDC@91061|Bacilli,1ZD8U@1386|Bacillus 91061|Bacilli S permease pbuO_1 - - ko:K06901 - - - - ko00000,ko02000 2.A.1.40 - - Xan_ur_permease k141_9933_1 1121938.AUDY01000008_gene1711 4.63e-79 243.0 COG2996@1|root,COG2996@2|Bacteria,1TQ1Z@1239|Firmicutes,4HDAZ@91061|Bacilli,3NDHM@45667|Halobacillus 91061|Bacilli S S1 domain yitL - - ko:K00243 - - - - ko00000 - - - S1_2 k141_11098_1 983545.Glaag_3742 2.29e-53 190.0 COG1629@1|root,COG4206@1|root,COG4206@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria,4652I@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec k141_19406_1 1294265.JCM21738_1708 1.6e-108 323.0 COG1113@1|root,COG1113@2|Bacteria,1TP97@1239|Firmicutes,4H9QX@91061|Bacilli,1ZDGG@1386|Bacillus 91061|Bacilli E COG1113 Gamma-aminobutyrate permease and related permeases ycgH GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03293 - - - - ko00000 2.A.3.1 - - AA_permease k141_17027_1 768670.Calni_0244 2.05e-22 98.6 COG0697@1|root,COG0697@2|Bacteria,2GFFP@200930|Deferribacteres 200930|Deferribacteres EG EamA-like transporter family - - - - - - - - - - - - EamA k141_13572_1 545697.HMPREF0216_00532 3.15e-24 102.0 COG2199@1|root,COG3706@2|Bacteria,1TQMM@1239|Firmicutes,24BS4@186801|Clostridia,36FXS@31979|Clostridiaceae 186801|Clostridia T Diguanylate cyclase - - - - - - - - - - - - GAF,GGDEF,SpoOE-like k141_25370_1 441769.ABFU01000037_gene211 1.38e-52 166.0 COG1141@1|root,COG1141@2|Bacteria,1VAC2@1239|Firmicutes,4HKG7@91061|Bacilli,1ZHTS@1386|Bacillus 91061|Bacilli C Ferredoxin fer GO:0003674,GO:0003824,GO:0005488,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114 - ko:K05337 - - - - ko00000 - - - Fer4_13 k141_23044_1 1294265.JCM21738_3325 3.15e-256 704.0 COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,4HB1H@91061|Bacilli,1ZAV8@1386|Bacillus 91061|Bacilli K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth sigA - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 k141_21794_1 1117647.M5M_09025 1.43e-77 253.0 COG1629@1|root,COG4771@2|Bacteria,1MVFB@1224|Proteobacteria,1RNMS@1236|Gammaproteobacteria,1J4QU@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec k141_32373_2 218284.CCDN010000001_gene117 7.08e-52 166.0 2DV4S@1|root,32UYM@2|Bacteria,1VA7R@1239|Firmicutes,4HMUX@91061|Bacilli,1ZI1G@1386|Bacillus 91061|Bacilli S Putative coat protein ylbD - - - - - - - - - - - YlbD_coat k141_18274_1 338963.Pcar_2327 1.54e-47 166.0 COG0061@1|root,COG0061@2|Bacteria,1MUBC@1224|Proteobacteria,42MP8@68525|delta/epsilon subdivisions,2WKMR@28221|Deltaproteobacteria,43SZE@69541|Desulfuromonadales 28221|Deltaproteobacteria F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP nadK - 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 - R00104 RC00002,RC00078 ko00000,ko00001,ko01000 - - - NAD_kinase k141_30009_1 218284.CCDN010000006_gene3513 2.04e-112 332.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,1ZBKX@1386|Bacillus 91061|Bacilli I Belongs to the thiolase family fadA - 2.3.1.16 ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 M00087,M00113 R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095 RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955 ko00000,ko00001,ko00002,ko01000 - - - Thiolase_C,Thiolase_N k141_35963_1 1071073.KI530547_gene3806 6.98e-50 163.0 COG3728@1|root,COG3728@2|Bacteria,1VAD9@1239|Firmicutes,4HKES@91061|Bacilli,1ZHGN@1386|Bacillus 91061|Bacilli L Terminase small subunit - - - ko:K07474 - - - - ko00000 - - - Terminase_2 k141_23045_1 1279017.AQYJ01000028_gene2137 1.02e-33 133.0 COG0308@1|root,COG0308@2|Bacteria,1PJTM@1224|Proteobacteria,1SYS3@1236|Gammaproteobacteria,4672R@72275|Alteromonadaceae 1236|Gammaproteobacteria E Peptidase family M1 domain - - 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - ERAP1_C,Peptidase_M1 k141_37175_1 1443125.Z962_p0018 2.91e-10 63.5 COG3723@1|root,COG3723@2|Bacteria,1UNDF@1239|Firmicutes,24CI5@186801|Clostridia,36VUF@31979|Clostridiaceae 186801|Clostridia L RecT family recT - - ko:K07455 - - - - ko00000,ko03400 - - - RecT k141_19408_2 1294265.JCM21738_3969 8.12e-108 311.0 COG1057@1|root,COG1057@2|Bacteria,1V3SK@1239|Firmicutes,4HGXK@91061|Bacilli,1ZFIV@1386|Bacillus 91061|Bacilli H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) nadD GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 ko:K00969 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like k141_5133_1 1219076.N646_3800 4.75e-25 100.0 COG3608@1|root,COG3608@2|Bacteria,1MUAA@1224|Proteobacteria,1RNQQ@1236|Gammaproteobacteria,1XSB8@135623|Vibrionales 135623|Vibrionales S Succinylglutamate desuccinylase / Aspartoacylase family - - 3.5.1.125 ko:K15784 ko00260,ko01100,map00260,map01100 - R09801 RC00064,RC00300 ko00000,ko00001,ko01000 - - - AstE_AspA k141_24145_6 1042377.AFPJ01000042_gene1011 1.52e-32 125.0 2DB6N@1|root,2Z7HZ@2|Bacteria,1PQ9P@1224|Proteobacteria,1RRV9@1236|Gammaproteobacteria,465YP@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF4392) - - - - - - - - - - - - DUF4392 k141_1537_1 1280949.HAD_10825 1.96e-18 85.5 COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,2TSGE@28211|Alphaproteobacteria 28211|Alphaproteobacteria U COG0457 FOG TPR repeat - - - - - - - - - - - - Sulfotransfer_3,TPR_16,TPR_19,TPR_2,TPR_8 k141_1537_2 1042377.AFPJ01000043_gene887 3.16e-50 179.0 COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,1RYP9@1236|Gammaproteobacteria,465IE@72275|Alteromonadaceae 1236|Gammaproteobacteria E ERAP1-like C-terminal domain - - 3.4.11.14 ko:K01263 - - - - ko00000,ko01000 - - - ERAP1_C,Peptidase_M1 k141_34844_1 1122197.ATWI01000014_gene4 1.89e-61 199.0 COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,1RR4F@1236|Gammaproteobacteria,465JZ@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG2801 Transposase and inactivated derivatives - - - ko:K07497 - - - - ko00000 - - - HTH_21,rve k141_25410_1 661478.OP10G_0966 4.12e-17 80.5 COG0071@1|root,COG0071@2|Bacteria 2|Bacteria O Belongs to the small heat shock protein (HSP20) family hspX GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009267,GO:0009408,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0009991,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016310,GO:0019538,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0036294,GO:0040007,GO:0040008,GO:0042221,GO:0042594,GO:0043170,GO:0043207,GO:0043412,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045926,GO:0046777,GO:0048519,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0065007,GO:0070482,GO:0070887,GO:0071453,GO:0071456,GO:0071496,GO:0071704,GO:0071944,GO:0075136,GO:1901564 - ko:K06335,ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 k141_25410_2 1453501.JELR01000002_gene1278 3.51e-13 65.1 COG0824@1|root,COG0824@2|Bacteria,1MZFI@1224|Proteobacteria,1S8XF@1236|Gammaproteobacteria,467SW@72275|Alteromonadaceae 1236|Gammaproteobacteria S Thioesterase-like superfamily - - - ko:K07107 - - - - ko00000,ko01000 - - - 4HBT,4HBT_2 k141_33733_1 218284.CCDN010000001_gene1273 7.74e-138 411.0 COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,1TSAC@1239|Firmicutes,4HAJG@91061|Bacilli,1ZB2G@1386|Bacillus 91061|Bacilli L ATP-dependent DNA ligase ligD - 6.5.1.1 ko:K01971 ko03450,map03450 - R00381 RC00005 ko00000,ko00001,ko01000,ko03400 - - - DNA_ligase_A_M k141_33733_2 218284.CCDN010000001_gene1274 5.18e-137 392.0 COG1273@1|root,COG1273@2|Bacteria,1TSY5@1239|Firmicutes,4HC5V@91061|Bacilli,1ZB9J@1386|Bacillus 91061|Bacilli L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD ku GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0097159,GO:1901363 - ko:K10979 ko03450,map03450 - - - ko00000,ko00001,ko03400 - - - Ku k141_13620_2 1116375.VEJY3_06030 0.0 1045.0 COG4987@1|root,COG4987@2|Bacteria,1QU1P@1224|Proteobacteria,1RQD7@1236|Gammaproteobacteria,1XUM9@135623|Vibrionales 135623|Vibrionales CO COG4987 ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components cydC - - ko:K16012 ko02010,map02010 - - - ko00000,ko00001,ko02000 3.A.1.129 - - ABC_membrane,ABC_tran k141_13620_3 1116375.VEJY3_06035 1.53e-40 147.0 COG4988@1|root,COG4988@2|Bacteria,1QU1N@1224|Proteobacteria,1RNPI@1236|Gammaproteobacteria,1XUSA@135623|Vibrionales 135623|Vibrionales CO COG4988 ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components cydD - - ko:K16013 ko02010,map02010 - - - ko00000,ko00001,ko02000 3.A.1.129 - - ABC_membrane,ABC_tran k141_11121_1 218284.CCDN010000002_gene2293 2.1e-201 568.0 COG0477@1|root,COG2814@2|Bacteria,1TPVC@1239|Firmicutes,4HB6R@91061|Bacilli,1ZS47@1386|Bacillus 91061|Bacilli EGP Major Facilitator Superfamily - - - ko:K08152 - - - - ko00000,ko02000 2.A.1.2 - - MFS_1,Sugar_tr k141_28928_2 1453501.JELR01000001_gene1885 1.63e-300 825.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,465UR@72275|Alteromonadaceae 1236|Gammaproteobacteria C Belongs to the aldehyde dehydrogenase family - - 1.2.1.3 ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_28928_4 1279017.AQYJ01000021_gene2941 9.94e-267 733.0 COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,1RNS6@1236|Gammaproteobacteria,465DM@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA kbl GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008144,GO:0016874,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.3.1.29 ko:K00639 ko00260,map00260 - R00371 RC00004,RC00394 ko00000,ko00001,ko01000,ko01007 - - iECW_1372.ECW_m3896,iEKO11_1354.EKO11_0103,iPC815.YPO0059,iWFL_1372.ECW_m3896 Aminotran_1_2 k141_28928_8 1117647.M5M_06325 3.62e-109 320.0 COG1075@1|root,COG1075@2|Bacteria,1MXXB@1224|Proteobacteria,1RZRM@1236|Gammaproteobacteria,1J8PY@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - - - - - - - - - - Lipase_2 k141_28928_9 395961.Cyan7425_1567 5.37e-17 82.0 2BWW9@1|root,33HUD@2|Bacteria 2|Bacteria S Protein of unknown function (DUF1439) - - - - - - - - - - - - DUF1439 k141_28928_10 1453501.JELR01000001_gene1881 4.98e-210 591.0 COG0025@1|root,COG0025@2|Bacteria,1MW5T@1224|Proteobacteria,1RPH6@1236|Gammaproteobacteria,467E9@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0025 NhaP-type Na H and K H antiporters nhaP - - ko:K03316 - - - - ko00000 2.A.36 - - Na_H_Exchanger,cNMP_binding k141_28928_11 1453501.JELR01000001_gene1880 8.09e-317 870.0 COG0069@1|root,COG0069@2|Bacteria,1MU7B@1224|Proteobacteria,1RP1C@1236|Gammaproteobacteria,46481@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the glutamate synthase family - - - - - - - - - - - - Glu_synthase k141_28928_12 1453501.JELR01000001_gene1879 7.43e-188 530.0 COG1533@1|root,COG1533@2|Bacteria,1MW0H@1224|Proteobacteria,1RQNF@1236|Gammaproteobacteria,465H5@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG1533 DNA repair photolyase - - - - - - - - - - - - Radical_SAM k141_28928_13 1415754.JQMK01000012_gene1105 1.72e-28 105.0 COG2827@1|root,COG2827@2|Bacteria,1N6PA@1224|Proteobacteria,1SCBH@1236|Gammaproteobacteria,46947@72275|Alteromonadaceae 1236|Gammaproteobacteria L endonuclease containing a URI domain yhbQ GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - ko:K07461 - - - - ko00000 - - - GIY-YIG k141_28928_14 1453501.JELR01000001_gene2359 2.53e-14 68.2 COG5660@1|root,COG5660@2|Bacteria,1NH4R@1224|Proteobacteria,1SH4J@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Transmembrane anti-sigma factor - - - - - - - - - - - - zf-HC2 k141_17044_1 218284.CCDN010000001_gene62 1.99e-87 269.0 COG2233@1|root,COG2233@2|Bacteria,1TQKX@1239|Firmicutes,4HAEU@91061|Bacilli,1ZBWN@1386|Bacillus 91061|Bacilli F Xanthine uracil pyrP - - ko:K02824 - - - - ko00000,ko02000 2.A.40.1.1,2.A.40.1.2 - - Xan_ur_permease k141_8797_1 218284.CCDN010000001_gene792 3.46e-141 402.0 COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,4HAB1@91061|Bacilli,1ZBQ5@1386|Bacillus 91061|Bacilli P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system pstB - 3.6.3.27 ko:K02036 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 - iSB619.SA_RS06920 ABC_tran k141_33734_2 218284.CCDN010000008_gene4215 3.73e-78 242.0 COG1488@1|root,COG1488@2|Bacteria,1TPDW@1239|Firmicutes,4HAI4@91061|Bacilli,1ZCGY@1386|Bacillus 91061|Bacilli H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP pncB2 - 6.3.4.21 ko:K00763 ko00760,ko01100,map00760,map01100 - R01724 RC00033 ko00000,ko00001,ko01000 - - - QRPTase_C,QRPTase_N k141_14634_1 218284.CCDN010000009_gene4310 1.61e-102 317.0 COG1289@1|root,COG1289@2|Bacteria,1U18W@1239|Firmicutes,4IJPB@91061|Bacilli,1ZDV7@1386|Bacillus 91061|Bacilli S Fusaric acid resistance protein-like - - - - - - - - - - - - FUSC,FUSC_2 k141_1538_1 1294265.JCM21738_3040 5.6e-98 296.0 COG2233@1|root,COG2233@2|Bacteria,1TQ0A@1239|Firmicutes,4HA6X@91061|Bacilli,1ZD5W@1386|Bacillus 91061|Bacilli F Xanthine uracil ywdJ GO:0003674,GO:0005215,GO:0005345,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006863,GO:0008150,GO:0015205,GO:0015851,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0042906,GO:0042907,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072530,GO:1904823 - - - - - - - - - - Xan_ur_permease k141_23068_1 1453501.JELR01000001_gene3132 9.9e-112 328.0 COG1946@1|root,COG1946@2|Bacteria,1NAQM@1224|Proteobacteria,1RR0K@1236|Gammaproteobacteria,4645G@72275|Alteromonadaceae 1236|Gammaproteobacteria I acyl-CoA thioesterase - - 3.1.2.20 ko:K01073 - - - - ko00000,ko01000 - - - 4HBT_3 k141_9956_2 218284.CCDN010000002_gene2184 1.16e-222 623.0 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli,1ZAXK@1386|Bacillus 91061|Bacilli C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively aldA - 1.2.1.21,1.2.1.22 ko:K07248 ko00620,ko00630,ko01120,map00620,map00630,map01120 - R00203,R01333,R01446 RC00080,RC00104,RC00242 ko00000,ko00001,ko01000 - - - Aldedh k141_5165_1 42565.FP66_12260 4.16e-142 404.0 COG0720@1|root,COG0720@2|Bacteria,1MXVT@1224|Proteobacteria,1RN6H@1236|Gammaproteobacteria,1XIXT@135619|Oceanospirillales 135619|Oceanospirillales H COG0720 6-pyruvoyl-tetrahydropterin synthase - - - - - - - - - - - - PTPS k141_30025_1 1071073.KI530534_gene815 1.06e-115 342.0 COG0172@1|root,COG0172@2|Bacteria,1TP4W@1239|Firmicutes,4H9Y4@91061|Bacilli,1ZCBQ@1386|Bacillus 91061|Bacilli J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) serS - 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Seryl_tRNA_N,tRNA-synt_2b k141_530_1 1211814.CAPG01000098_gene4387 1.21e-08 50.8 2DR8Z@1|root,33AQV@2|Bacteria,1VK7N@1239|Firmicutes,4HRWZ@91061|Bacilli,1ZISI@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_35983_1 1294265.JCM21738_1869 1.23e-136 402.0 COG0243@1|root,COG0243@2|Bacteria,1VTS0@1239|Firmicutes,4HAZ4@91061|Bacilli,1ZBMY@1386|Bacillus 91061|Bacilli C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - ko:K00372 ko00910,ko01120,map00910,map01120 M00531 R00798,R01106 RC02812 ko00000,ko00001,ko00002,ko01000 - - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding k141_33735_1 1453501.JELR01000002_gene745 0.000876 41.6 COG3326@1|root,COG3326@2|Bacteria,1N6YM@1224|Proteobacteria,1SCMX@1236|Gammaproteobacteria,468PH@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF1294) - - - - - - - - - - - - CSD,DUF1294 k141_33735_2 1042377.AFPJ01000043_gene892 3.09e-104 302.0 COG0454@1|root,COG0456@2|Bacteria,1QU0C@1224|Proteobacteria,1S503@1236|Gammaproteobacteria 1236|Gammaproteobacteria K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - - - - - - - - - - Acetyltransf_1 k141_12427_2 1279017.AQYJ01000023_gene3142 2.36e-132 385.0 COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,1RPHI@1236|Gammaproteobacteria,464GH@72275|Alteromonadaceae 1236|Gammaproteobacteria J histidyl-tRNA synthetase hisS GO:0003674,GO:0003824,GO:0004812,GO:0004821,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006427,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iE2348C_1286.E2348C_2797,iECNA114_1301.ECNA114_2592,iECSF_1327.ECSF_2358 HGTP_anticodon,tRNA-synt_His k141_9957_1 1385514.N782_12480 2.15e-116 363.0 COG0454@1|root,COG0456@2|Bacteria,1TQQA@1239|Firmicutes,4HBXN@91061|Bacilli,2YBGI@289201|Pontibacillus 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10 k141_34847_1 1280001.BAOA01000171_gene3696 1.35e-95 288.0 COG2966@1|root,COG3610@1|root,COG2966@2|Bacteria,COG3610@2|Bacteria,1RAQ0@1224|Proteobacteria,1RP2P@1236|Gammaproteobacteria,1XUE6@135623|Vibrionales 135623|Vibrionales S Putative threonine/serine exporter - - - - - - - - - - - - ThrE,ThrE_2 k141_23069_1 1453501.JELR01000001_gene3043 1.62e-109 319.0 COG1589@1|root,COG1589@2|Bacteria,1N0T7@1224|Proteobacteria,1S9FJ@1236|Gammaproteobacteria,467QJ@72275|Alteromonadaceae 1236|Gammaproteobacteria D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly ftsQ GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0042802,GO:0043093,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 - ko:K03589 ko04112,map04112 - - - ko00000,ko00001,ko03036 - - - FtsQ,POTRA_1 k141_4057_1 221109.22776413 2.62e-67 226.0 COG1404@1|root,COG1404@2|Bacteria,1TPH1@1239|Firmicutes,4HBQH@91061|Bacilli,23IZR@182709|Oceanobacillus 91061|Bacilli O PA domain prtS - 3.4.21.110,3.4.21.96 ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 - - - ko00000,ko00001,ko01000,ko01002,ko03110 - - - FIVAR,Gram_pos_anchor,Inhibitor_I9,PA,Peptidase_S8,SLH,YSIRK_signal,fn3_5 k141_37195_2 218284.CCDN010000001_gene1747 9.79e-212 587.0 COG0346@1|root,COG0346@2|Bacteria,1TP7I@1239|Firmicutes,4H9ND@91061|Bacilli,1ZBUA@1386|Bacillus 91061|Bacilli E COG0346 Lactoylglutathione lyase and related lyases ykcA - - ko:K15975 - - - - ko00000 - - - Glyoxalase k141_37195_3 935837.JAEK01000010_gene107 5.96e-43 145.0 COG0400@1|root,COG0400@2|Bacteria,1TPBY@1239|Firmicutes,4HB45@91061|Bacilli,1ZAQZ@1386|Bacillus 91061|Bacilli S Carboxylesterase yahD - - ko:K06999 - - - - ko00000 - - - Abhydrolase_2,DLH k141_19432_2 1042377.AFPJ01000054_gene1715 0.0 879.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1MUJ3@1224|Proteobacteria,1RRN4@1236|Gammaproteobacteria,4674P@72275|Alteromonadaceae 1236|Gammaproteobacteria EU Prolyl oligopeptidase, N-terminal beta-propeller domain - - - - - - - - - - - - PD40,Peptidase_S9,Peptidase_S9_N k141_33736_2 1121938.AUDY01000006_gene3092 1.42e-29 108.0 COG2919@1|root,COG2919@2|Bacteria,1VKC5@1239|Firmicutes,4HR53@91061|Bacilli,3NEXK@45667|Halobacillus 91061|Bacilli D Septum formation initiator divIC - - ko:K13052 - - - - ko00000,ko03036 - - - DivIC k141_25413_1 1294265.JCM21738_4678 2.79e-43 141.0 2F8H8@1|root,3082J@2|Bacteria,1U2PE@1239|Firmicutes,4ICCB@91061|Bacilli,1ZK9K@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_12428_1 218284.CCDN010000007_gene3939 1.43e-45 147.0 COG4844@1|root,COG4844@2|Bacteria,1VB5Q@1239|Firmicutes,4HKJX@91061|Bacilli,1ZHXV@1386|Bacillus 91061|Bacilli S Belongs to the UPF0741 family ywzC - - - - - - - - - - - DUF1450 k141_34848_1 1122137.AQXF01000001_gene2761 6.25e-18 87.0 COG2866@1|root,COG2866@2|Bacteria,1N9W9@1224|Proteobacteria,2U2SA@28211|Alphaproteobacteria 28211|Alphaproteobacteria E carboxypeptidase - - - - - - - - - - - - Peptidase_M14 k141_20566_1 1279017.AQYJ01000021_gene2864 3.3e-282 774.0 COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,1RNQA@1236|Gammaproteobacteria,464ZZ@72275|Alteromonadaceae 1236|Gammaproteobacteria G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis eno GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 - - iPC815.YPO3376 Enolase_C,Enolase_N k141_32392_2 1279017.AQYJ01000025_gene718 5.89e-131 384.0 COG4585@1|root,COG4585@2|Bacteria,1R6FX@1224|Proteobacteria,1S0UD@1236|Gammaproteobacteria,467NI@72275|Alteromonadaceae 1236|Gammaproteobacteria T Histidine kinase desK - 2.7.13.3 ko:K07778 ko02020,map02020 M00479 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA_3 k141_532_1 1274524.BSONL12_10656 3.83e-50 159.0 COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,4HKE9@91061|Bacilli,1ZH7M@1386|Bacillus 91061|Bacilli J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome rpsO GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02956 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S15 k141_532_2 1294265.JCM21738_361 5.86e-18 81.3 COG0196@1|root,COG0196@2|Bacteria,1TPKS@1239|Firmicutes,4H9KE@91061|Bacilli,1ZBFH@1386|Bacillus 91061|Bacilli H Belongs to the ribF family ribF - 2.7.1.26,2.7.7.2 ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS06310 FAD_syn,Flavokinase k141_1540_1 935836.JAEL01000005_gene2677 6.4e-44 150.0 2BZV8@1|root,30HHG@2|Bacteria,1V68P@1239|Firmicutes,4HHRU@91061|Bacilli,1ZF2B@1386|Bacillus 91061|Bacilli S Replication-relaxation - - - - - - - - - - - - Replic_Relax k141_7494_2 218284.CCDN010000004_gene3055 4.84e-103 308.0 COG4134@1|root,COG4134@2|Bacteria,1TR3G@1239|Firmicutes,4HAW1@91061|Bacilli,1ZD00@1386|Bacillus 91061|Bacilli S Bacterial extracellular solute-binding protein - - - ko:K02055 ko02024,map02024 M00193 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11 - - SBP_bac_8 k141_35984_1 218284.CCDN010000002_gene1982 2.41e-06 47.8 COG0041@1|root,COG0041@2|Bacteria,1V1MV@1239|Firmicutes,4HFR7@91061|Bacilli,1ZFRE@1386|Bacillus 91061|Bacilli F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) purE - 5.4.99.18 ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07405 RC01947 ko00000,ko00001,ko00002,ko01000 - - - AIRC k141_13638_1 1453501.JELR01000002_gene529 5.63e-98 303.0 COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,1RMT7@1236|Gammaproteobacteria,466B9@72275|Alteromonadaceae 1236|Gammaproteobacteria S Bacterial protein of unknown function (DUF885) - - - - - - - - - - - - DUF885 k141_23104_1 218284.CCDN010000001_gene72 2.02e-151 426.0 COG0325@1|root,COG0325@2|Bacteria,1TRDN@1239|Firmicutes,4HC45@91061|Bacilli,1ZARM@1386|Bacillus 91061|Bacilli S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis ylmE GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 - ko:K06997 - - - - ko00000 - - - Ala_racemase_N k141_23104_2 218284.CCDN010000001_gene73 6.18e-42 144.0 COG1496@1|root,COG1496@2|Bacteria,1TS34@1239|Firmicutes,4HFUM@91061|Bacilli,1ZBZZ@1386|Bacillus 91061|Bacilli S Belongs to the multicopper oxidase YfiH RL5 family ylmD GO:0003674,GO:0005488,GO:0005507,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - ko:K05810 - - - - ko00000,ko01000 - - - Cu-oxidase_4 k141_2771_1 985054.JQEZ01000002_gene3846 1.46e-95 295.0 COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,2TT5E@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q COG3653 N-acyl-D-aspartate D-glutamate deacylase - - - - - - - - - - - - Amidohydro_3 k141_4071_1 796606.BMMGA3_03320 3.03e-114 341.0 COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,4HA6M@91061|Bacilli,1ZD4Q@1386|Bacillus 91061|Bacilli J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family rumA_1 - 2.1.1.190,2.1.1.35 ko:K00557,ko:K03215 - - - - ko00000,ko01000,ko03009,ko03016 - - - TRAM,tRNA_U5-meth_tr k141_8817_2 1042377.AFPJ01000024_gene792 3.98e-48 163.0 COG0810@1|root,COG0810@2|Bacteria 2|Bacteria M energy transducer activity - - - ko:K03646,ko:K03832 - - - - ko00000,ko02000 2.C.1.1,2.C.1.2 - - TonB_C k141_8817_3 1453501.JELR01000002_gene668 0.0 1074.0 COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,1RMP2@1236|Gammaproteobacteria,464EW@72275|Alteromonadaceae 1236|Gammaproteobacteria EG Belongs to the IlvD Edd family ilvD - 4.2.1.9 ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R01209,R04441,R05070 RC00468,RC01714 ko00000,ko00001,ko00002,ko01000 - - - ILVD_EDD k141_8817_5 458817.Shal_0545 7.6e-91 279.0 COG2819@1|root,COG2819@2|Bacteria,1RB1X@1224|Proteobacteria,1RY80@1236|Gammaproteobacteria,2QBJQ@267890|Shewanellaceae 1236|Gammaproteobacteria S Putative esterase - - - ko:K07017 - - - - ko00000 - - - Esterase k141_8817_6 1453501.JELR01000002_gene666 9.81e-214 597.0 COG0624@1|root,COG0624@2|Bacteria,1MVBR@1224|Proteobacteria,1RNDG@1236|Gammaproteobacteria,4653S@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the peptidase M20A family. ArgE subfamily argE GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0008777,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019752,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0046914,GO:0050897,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.1.16 ko:K01438 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R00669,R09107 RC00064,RC00300 ko00000,ko00001,ko00002,ko01000 - - iECUMN_1333.ECUMN_4488 M20_dimer,Peptidase_M20,Peptidase_M28 k141_8817_7 1453501.JELR01000002_gene645 3.07e-142 409.0 COG0697@1|root,COG0697@2|Bacteria,1MWMC@1224|Proteobacteria,1RQST@1236|Gammaproteobacteria,464KV@72275|Alteromonadaceae 1236|Gammaproteobacteria EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily yigM GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - EamA k141_8817_8 1453501.JELR01000002_gene644 1.73e-53 172.0 COG1777@1|root,COG1777@2|Bacteria,1N78A@1224|Proteobacteria,1SDX8@1236|Gammaproteobacteria 1236|Gammaproteobacteria K ROK family - - - - - - - - - - - - - k141_8817_9 497964.CfE428DRAFT_2468 9.25e-81 251.0 COG0384@1|root,COG0384@2|Bacteria,46SN8@74201|Verrucomicrobia 74201|Verrucomicrobia S PFAM Phenazine biosynthesis PhzC PhzF protein - - - - - - - - - - - - PhzC-PhzF k141_8817_10 1279017.AQYJ01000028_gene2194 9.18e-271 745.0 COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,1RP0Q@1236|Gammaproteobacteria,4650Z@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0306 Phosphate sulphate permeases pitA GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661 - ko:K03306 - - - - ko00000 2.A.20 - - PHO4 k141_18330_1 935836.JAEL01000096_gene3495 9.97e-161 460.0 COG0486@1|root,COG0486@2|Bacteria,1TPJF@1239|Firmicutes,4HA06@91061|Bacilli,1ZBTZ@1386|Bacillus 91061|Bacilli S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 mnmE - - ko:K03650 - - R08701 RC00053,RC00209,RC00870 ko00000,ko01000,ko03016 - - - MMR_HSR1,MnmE_helical,TrmE_N k141_11160_1 1128421.JAGA01000003_gene3678 8.28e-26 113.0 COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2NQCZ@2323|unclassified Bacteria 2|Bacteria K NB-ARC domain - - - - - - - - - - - - AAA_16,AAA_22,BTAD,NB-ARC,TPR_10,TPR_12,TPR_8,Trans_reg_C k141_28944_1 1279017.AQYJ01000024_gene946 3.6e-34 127.0 COG3486@1|root,COG3486@2|Bacteria,1MX36@1224|Proteobacteria,1RZXS@1236|Gammaproteobacteria,46A75@72275|Alteromonadaceae 1236|Gammaproteobacteria Q L-lysine 6-monooxygenase (NADPH-requiring) - - 1.14.13.195,1.14.13.196,1.14.13.59 ko:K03897,ko:K10531 ko00310,ko01120,map00310,map01120 - R00448 RC00298 ko00000,ko00001,ko01000 - - - K_oxygenase k141_28944_2 1287276.X752_06070 1.65e-67 224.0 COG4264@1|root,COG4264@2|Bacteria,1MVUU@1224|Proteobacteria,2U2SG@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q IucA IucC family protein - - 6.3.2.39 ko:K03895 ko00310,ko01120,map00310,map01120 - R10091 RC00064,RC00090 ko00000,ko00001,ko01000 - - - AMP-binding,AMP-binding_C,FhuF,IucA_IucC k141_31302_1 1042377.AFPJ01000043_gene884 6.36e-170 479.0 COG0388@1|root,COG0388@2|Bacteria,1MXG5@1224|Proteobacteria,1RP7S@1236|Gammaproteobacteria,466Q1@72275|Alteromonadaceae 1236|Gammaproteobacteria S Carbon-nitrogen hydrolase - - - - - - - - - - - - CN_hydrolase k141_31302_2 1453501.JELR01000002_gene870 7.46e-84 272.0 COG1629@1|root,COG4771@2|Bacteria,1MVFB@1224|Proteobacteria,1RNMS@1236|Gammaproteobacteria,466BD@72275|Alteromonadaceae 1236|Gammaproteobacteria P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec k141_13639_1 1294265.JCM21738_2453 2.15e-140 400.0 COG3858@1|root,COG3858@2|Bacteria,1TQK2@1239|Firmicutes,4HTBB@91061|Bacilli,1ZEKU@1386|Bacillus 91061|Bacilli M Glycosyl hydrolases family 18 - - - ko:K06306 - - - - ko00000 - - - Glyco_hydro_18,LysM k141_6454_1 218284.CCDN010000004_gene3119 1.56e-128 375.0 COG1301@1|root,COG1301@2|Bacteria,1TPME@1239|Firmicutes,4H9T7@91061|Bacilli,1ZCSU@1386|Bacillus 91061|Bacilli C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family gltP - - - - - - - - - - - SDF k141_37216_1 398511.BpOF4_12045 1.27e-82 257.0 COG4427@1|root,COG4427@2|Bacteria,1TZ5M@1239|Firmicutes,4HAQV@91061|Bacilli,1ZCQX@1386|Bacillus 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2332) - - - - - - - - - - - - DUF2332 k141_37216_2 743719.PaelaDRAFT_1180 1.99e-60 189.0 COG0346@1|root,COG0346@2|Bacteria,1V6PX@1239|Firmicutes,4HIFZ@91061|Bacilli,26YNT@186822|Paenibacillaceae 91061|Bacilli E lactoylglutathione lyase activity - - - - - - - - - - - - - k141_9977_1 211586.SO_0341 8.7e-18 97.1 COG2202@1|root,COG3292@1|root,COG5001@1|root,COG2202@2|Bacteria,COG3292@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,2Q8ZG@267890|Shewanellaceae 1236|Gammaproteobacteria T Two component regulator three Y domain protein - - - - - - - - - - - - EAL,GGDEF,PAS_3,PAS_9,Reg_prop,Y_Y_Y k141_9977_2 1248232.BANQ01000063_gene2413 8.38e-26 117.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMV2@1236|Gammaproteobacteria,1XSAN@135623|Vibrionales 135623|Vibrionales T methyl-accepting chemotaxis protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal,sCache_2 k141_7516_1 672.VV93_v1c17490 4.23e-64 211.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XX1J@135623|Vibrionales 135623|Vibrionales T Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal k141_32415_1 1121938.AUDY01000011_gene591 1.72e-86 264.0 COG1087@1|root,COG1087@2|Bacteria,1TQ7N@1239|Firmicutes,4IS9Q@91061|Bacilli 91061|Bacilli M UDPglucose 4-epimerase - - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase,GDP_Man_Dehyd k141_14657_1 218284.CCDN010000002_gene2271 4.85e-109 322.0 COG1902@1|root,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,4HAS5@91061|Bacilli,1ZB1N@1386|Bacillus 91061|Bacilli C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family yqiG - - - - - - - - - - - Oxidored_FMN k141_4072_1 1294265.JCM21738_5484 1.19e-24 98.6 COG2194@1|root,COG2194@2|Bacteria,1UZ64@1239|Firmicutes,4HF6P@91061|Bacilli,1ZQJH@1386|Bacillus 91061|Bacilli S KinB-signalling pathway activation in sporulation - - - ko:K06349 - - - - ko00000 - - - KbaA k141_4072_2 935836.JAEL01000067_gene1707 6.57e-65 205.0 COG0726@1|root,COG0726@2|Bacteria,1UZJN@1239|Firmicutes,4IPMR@91061|Bacilli,1ZBAU@1386|Bacillus 91061|Bacilli G xylanase chitin deacetylase pdaB - - - - - - - - - - - Polysacc_deac_1 k141_11161_1 1382306.JNIM01000001_gene453 1.09e-10 63.2 COG0671@1|root,COG0671@2|Bacteria,2G93T@200795|Chloroflexi 200795|Chloroflexi I phosphoesterase, PA-phosphatase related - - - - - - - - - - - - PAP2 k141_12471_1 935836.JAEL01000083_gene1123 1.41e-108 317.0 COG0247@1|root,COG0247@2|Bacteria,1TPFC@1239|Firmicutes,4HAKC@91061|Bacilli,1ZCUT@1386|Bacillus 91061|Bacilli C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source lutA - - ko:K18928 - - - - ko00000 - - - CCG k141_5214_1 1449976.KALB_4047 6.84e-19 88.2 COG1562@1|root,COG1562@2|Bacteria,2GJN2@201174|Actinobacteria,4E0VU@85010|Pseudonocardiales 201174|Actinobacteria I Squalene phytoene synthase crtB GO:0003674,GO:0003824,GO:0004337,GO:0004659,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016108,GO:0016109,GO:0016114,GO:0016116,GO:0016117,GO:0016740,GO:0016765,GO:0016767,GO:0042440,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046148,GO:0071704,GO:1901576 2.5.1.32,2.5.1.99 ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 M00097 R02065,R04218,R07270,R10177 RC00362,RC01101,RC02869 ko00000,ko00001,ko00002,ko01000,ko01006 - - - SQS_PSY k141_33756_1 1121943.KB900000_gene1219 9.58e-12 65.1 COG0620@1|root,COG0620@2|Bacteria,1MUI9@1224|Proteobacteria,1RMBA@1236|Gammaproteobacteria,1XHJ4@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation metE - 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_1,Meth_synt_2 k141_33756_2 1453501.JELR01000002_gene220 1.47e-194 543.0 COG0583@1|root,COG0583@2|Bacteria,1MUIX@1224|Proteobacteria,1RRF3@1236|Gammaproteobacteria,4645H@72275|Alteromonadaceae 1236|Gammaproteobacteria K Transcriptional regulator metR - - ko:K03576 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate k141_33756_3 1453501.JELR01000002_gene221 2.39e-81 246.0 COG3038@1|root,COG3038@2|Bacteria,1RBP8@1224|Proteobacteria,1S563@1236|Gammaproteobacteria,468V5@72275|Alteromonadaceae 1236|Gammaproteobacteria C Prokaryotic cytochrome b561 cybB - - ko:K12262 - - - - ko00000 - - - Ni_hydr_CYTB k141_33756_4 1042377.AFPJ01000052_gene1534 5.64e-47 168.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,4643Q@72275|Alteromonadaceae 1236|Gammaproteobacteria JKL DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation deaD GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003725,GO:0003727,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006417,GO:0006725,GO:0006807,GO:0006950,GO:0006996,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009266,GO:0009314,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009987,GO:0010468,GO:0010501,GO:0010556,GO:0010557,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019439,GO:0022607,GO:0022613,GO:0022618,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031330,GO:0032268,GO:0032270,GO:0033554,GO:0033592,GO:0034248,GO:0034250,GO:0034622,GO:0034641,GO:0034655,GO:0042254,GO:0042255,GO:0042273,GO:0042623,GO:0043170,GO:0043487,GO:0043488,GO:0043489,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045934,GO:0046483,GO:0046700,GO:0048255,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0061013,GO:0065003,GO:0065007,GO:0065008,GO:0070035,GO:0070417,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097617,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902369,GO:1902373,GO:1903311,GO:1903312,GO:2000112 3.6.4.13 ko:K05592 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,DEADboxA,DbpA,Helicase_C k141_9978_1 1453501.JELR01000002_gene483 1.12e-62 194.0 2CFS8@1|root,2ZFB8@2|Bacteria,1P495@1224|Proteobacteria,1STV4@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_23106_1 218284.CCDN010000001_gene1382 2e-140 403.0 COG1316@1|root,COG1316@2|Bacteria,1TSWQ@1239|Firmicutes,4HE66@91061|Bacilli,1ZBW5@1386|Bacillus 91061|Bacilli K COG1316 Transcriptional regulator msrR - - - - - - - - - - - LytR_cpsA_psr k141_32416_1 1382358.JHVN01000006_gene181 6.31e-38 133.0 COG1284@1|root,COG1284@2|Bacteria,1V3MX@1239|Firmicutes,4HHN4@91061|Bacilli 91061|Bacilli S Uncharacterised 5xTM membrane BCR, YitT family COG1284 - - - - - - - - - - - - YitT_membrane k141_12472_1 218284.CCDN010000005_gene3452 2.51e-54 181.0 COG0477@1|root,COG2814@2|Bacteria,1TRDJ@1239|Firmicutes,4H9Q9@91061|Bacilli,1ZBN7@1386|Bacillus 91061|Bacilli EGP Major facilitator superfamily yuxJ - - - - - - - - - - - MFS_1,Sugar_tr k141_18333_1 218284.CCDN010000001_gene1944 1.19e-128 372.0 COG0039@1|root,COG0039@2|Bacteria,1TPSY@1239|Firmicutes,4HB0Z@91061|Bacilli,1ZD2C@1386|Bacillus 91061|Bacilli C Belongs to the LDH MDH superfamily. LDH family ldh GO:0003674,GO:0003824,GO:0004457,GO:0004459,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 - R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 - - - Ldh_1_C,Ldh_1_N k141_6455_1 1179773.BN6_32170 1.19e-71 232.0 COG0076@1|root,COG0076@2|Bacteria,2GK3J@201174|Actinobacteria,4DXBU@85010|Pseudonocardiales 201174|Actinobacteria E Pyridoxal-dependent decarboxylase conserved domain - - - - - - - - - - - - Pyridoxal_deC k141_4073_1 1294265.JCM21738_1556 1.6e-07 50.4 COG3403@1|root,COG3403@2|Bacteria,1US5K@1239|Firmicutes,4HEQ9@91061|Bacilli,1ZDEK@1386|Bacillus 91061|Bacilli S YqcI/YcgG family - - - ko:K09190 - - - - ko00000 - - - YqcI_YcgG k141_4073_2 1294265.JCM21738_1555 7.64e-62 191.0 COG3011@1|root,COG3011@2|Bacteria,1V7DJ@1239|Firmicutes,4HIUD@91061|Bacilli,1ZH0A@1386|Bacillus 91061|Bacilli S protein conserved in bacteria yuxK - - - - - - - - - - - DUF393 k141_11163_1 218284.CCDN010000001_gene697 2.13e-97 293.0 COG0826@1|root,COG0826@2|Bacteria,1TPRE@1239|Firmicutes,4HBEG@91061|Bacilli,1ZC7K@1386|Bacillus 91061|Bacilli O COG0826 Collagenase and related proteases yrrO - - ko:K08303 ko05120,map05120 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_U32,Peptidase_U32_C k141_31303_1 218284.CCDN010000001_gene589 1.71e-109 323.0 COG0457@1|root,COG0457@2|Bacteria,1V7T7@1239|Firmicutes,4HKAH@91061|Bacilli,1ZS6N@1386|Bacillus 91061|Bacilli H Tetratricopeptide repeat ysoA - - - - - - - - - - - TPR_19 k141_28946_2 1408303.JNJJ01000028_gene3304 3.14e-74 229.0 COG0503@1|root,COG0503@2|Bacteria,1TPN9@1239|Firmicutes,4HB8I@91061|Bacilli,1ZAW9@1386|Bacillus 91061|Bacilli F pur operon repressor purR - - ko:K09685 - - - - ko00000,ko03000 - - - Pribosyltran,PuR_N k141_20593_1 1294265.JCM21738_2748 4.09e-135 384.0 COG2340@1|root,COG2340@2|Bacteria,1UYZ4@1239|Firmicutes,4HBTC@91061|Bacilli,1ZCGK@1386|Bacillus 91061|Bacilli S protein with SCP PR1 domains ylbC - - - - - - - - - - - CAP,CAP_assoc_N k141_25452_1 1294265.JCM21738_1960 9.4e-163 460.0 COG0053@1|root,COG0053@2|Bacteria,1TP5C@1239|Firmicutes,4HAP0@91061|Bacilli,1ZBSN@1386|Bacillus 91061|Bacilli P Dimerisation domain of Zinc Transporter cat - - - - - - - - - - - Cation_efflux,ZT_dimer k141_18334_1 316274.Haur_3629 1.66e-39 140.0 COG1073@1|root,COG1073@2|Bacteria,2G690@200795|Chloroflexi 200795|Chloroflexi S Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_5 k141_12473_1 1121921.KB898706_gene2536 8.93e-74 235.0 COG3934@1|root,COG3934@2|Bacteria,1N159@1224|Proteobacteria,1RRC1@1236|Gammaproteobacteria,2PN8K@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria G Cellulase (glycosyl hydrolase family 5) - - 3.2.1.78 ko:K19355 ko00051,map00051 - R01332 RC00467 ko00000,ko00001,ko01000 - - - Cellulase k141_13642_1 880070.Cycma_4594 1.97e-124 363.0 COG3385@1|root,COG3385@2|Bacteria,4NJC6@976|Bacteroidetes,47UVE@768503|Cytophagia 976|Bacteroidetes L PFAM Transposase DDE domain - - - - - - - - - - - - DDE_Tnp_1,DUF4372 k141_32417_1 198467.NP92_14585 1.06e-66 217.0 COG1674@1|root,COG1674@2|Bacteria,1TWB0@1239|Firmicutes,4HCGJ@91061|Bacilli,21X2C@150247|Anoxybacillus 91061|Bacilli D FtsK/SpoIIIE family - - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_SpoIIIE k141_33758_1 666686.B1NLA3E_12485 1.93e-69 230.0 COG2225@1|root,COG2225@2|Bacteria,1UA0Z@1239|Firmicutes,4HBPG@91061|Bacilli 91061|Bacilli C Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA glcB - 2.3.3.9 ko:K01638 ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200 M00012 R00472 RC00004,RC00308,RC02747 ko00000,ko00001,ko00002,ko01000 - - - Malate_synthase k141_14658_1 1385517.N800_06960 3.43e-45 153.0 COG3485@1|root,COG3485@2|Bacteria 2|Bacteria Q protocatechuate 3,4-dioxygenase activity - - 1.13.11.3 ko:K00449 ko00362,ko00624,ko01100,ko01120,ko01220,map00362,map00624,map01100,map01120,map01220 - R01631,R03549 RC00388,RC00953 br01602,ko00000,ko00001,ko01000 - - - Dioxygenase_C k141_27632_1 1396141.BATP01000033_gene4245 9.79e-38 145.0 COG0468@1|root,COG0468@2|Bacteria,46SIZ@74201|Verrucomicrobia,2ITWB@203494|Verrucomicrobiae 203494|Verrucomicrobiae L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage recA - - ko:K03553 ko03440,map03440 M00729 - - ko00000,ko00001,ko00002,ko03400 - - - RecA k141_30050_1 292459.STH371 2.46e-25 101.0 COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,2498Z@186801|Clostridia 186801|Clostridia E Belongs to the UPF0758 family radC - - ko:K03630 - - - - ko00000 - - - RadC k141_25453_1 562970.Btus_1004 3.29e-82 259.0 COG2225@1|root,COG2225@2|Bacteria,1TPE8@1239|Firmicutes,4H9ST@91061|Bacilli,27820@186823|Alicyclobacillaceae 91061|Bacilli C Belongs to the malate synthase family aceB - 2.3.3.9 ko:K01638 ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200 M00012 R00472 RC00004,RC00308,RC02747 ko00000,ko00001,ko00002,ko01000 - - - Malate_synthase k141_19454_1 1279017.AQYJ01000025_gene622 1.05e-74 253.0 COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1MUKF@1224|Proteobacteria,1RMW6@1236|Gammaproteobacteria,464JA@72275|Alteromonadaceae 1236|Gammaproteobacteria S DNA internalization-related competence protein ComEC Rec2 ycaI GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02238 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - Competence,DUF4131,Lactamase_B k141_9980_1 1279017.AQYJ01000026_gene197 6.17e-31 119.0 COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,1RN13@1236|Gammaproteobacteria,465K9@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine mtaD - 3.5.4.28,3.5.4.31 ko:K12960 ko00270,ko01100,map00270,map01100 - R09660 RC00477 ko00000,ko00001,ko01000 - - - Amidohydro_1 k141_20594_1 42565.FP66_11310 6.27e-115 339.0 COG3853@1|root,COG3853@2|Bacteria,1MY18@1224|Proteobacteria,1RZ1H@1236|Gammaproteobacteria,1XMQ5@135619|Oceanospirillales 135619|Oceanospirillales P Toxic anion resistance - - - - - - - - - - - - TelA k141_20616_2 935836.JAEL01000036_gene2978 3.85e-96 297.0 COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,4HBVK@91061|Bacilli,1ZBPB@1386|Bacillus 91061|Bacilli L DEAD DEAH box helicase deaD3 - 3.6.4.13 ko:K05592 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,Helicase_C k141_23150_1 1116375.VEJY3_20556 2.61e-90 273.0 COG1902@1|root,COG1902@2|Bacteria,1MVIX@1224|Proteobacteria,1RMFI@1236|Gammaproteobacteria,1XSZS@135623|Vibrionales 135623|Vibrionales C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family xenB - - - - - - - - - - - Oxidored_FMN k141_23150_2 674977.VMC_35620 1.55e-209 582.0 COG0109@1|root,COG0109@2|Bacteria,1MW3S@1224|Proteobacteria,1RNHC@1236|Gammaproteobacteria,1XUYC@135623|Vibrionales 135623|Vibrionales O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group cyoE - 2.5.1.141 ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 M00154 R07411 RC01786 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 - - - UbiA k141_34913_1 1116375.VEJY3_20376 2.63e-251 699.0 COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,1RMNZ@1236|Gammaproteobacteria,1XUS0@135623|Vibrionales 1236|Gammaproteobacteria F Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA - - 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 - - - AMP-binding,AMP-binding_C k141_34913_2 1116375.VEJY3_20381 0.0 923.0 COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,1S02D@1236|Gammaproteobacteria,1Y3B1@135623|Vibrionales 135623|Vibrionales C Dehydrogenase E1 component - - 1.2.4.4 ko:K11381 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 M00036 R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00027,RC00627,RC02743,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh,Transket_pyr,Transketolase_C k141_19476_1 1116375.VEJY3_05390 7.73e-144 410.0 28HXC@1|root,2Z831@2|Bacteria,1R415@1224|Proteobacteria,1RNDD@1236|Gammaproteobacteria,1XSGV@135623|Vibrionales 135623|Vibrionales - - EBIG1844 - - - - - - - - - - - - k141_19476_2 1219076.N646_0151 6.84e-177 493.0 COG4445@1|root,COG4445@2|Bacteria,1MVFE@1224|Proteobacteria,1RQ8Z@1236|Gammaproteobacteria,1XUJD@135623|Vibrionales 135623|Vibrionales FJ COG4445 Hydroxylase for synthesis of 2-methylthio-cis-ribozeatin in tRNA miaE - - ko:K06169 - - - - ko00000,ko01000,ko03016 - - - MiaE k141_2792_1 1280001.BAOA01000051_gene1547 4.57e-110 320.0 COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,1SPRE@1236|Gammaproteobacteria,1XUSU@135623|Vibrionales 135623|Vibrionales L COG0084 Mg-dependent DNase tatD - - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase k141_2792_2 1280001.BAOA01000051_gene1546 6.7e-242 666.0 COG0113@1|root,COG0113@2|Bacteria,1MWMW@1224|Proteobacteria,1RP6Q@1236|Gammaproteobacteria,1XSJ4@135623|Vibrionales 135623|Vibrionales H Belongs to the ALAD family hemB - 4.2.1.24 ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00036 RC00918,RC01781 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ALAD k141_2792_3 1116375.VEJY3_00480 1.49e-91 268.0 COG0454@1|root,COG0456@2|Bacteria,1N0SD@1224|Proteobacteria,1S9IW@1236|Gammaproteobacteria,1XY0U@135623|Vibrionales 135623|Vibrionales K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases SO4716 - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10 k141_2792_4 1116375.VEJY3_00490 2.32e-178 522.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,1XUAZ@135623|Vibrionales 135623|Vibrionales L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k141_12511_1 1120958.AULD01000009_gene841 1.12e-62 218.0 COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria,4FK5Q@85023|Microbacteriaceae 201174|Actinobacteria L Helix-hairpin-helix motif dnaE GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon k141_4096_1 195253.Syn6312_3024 2.43e-05 49.7 COG0454@1|root,COG0456@2|Bacteria,1G5GJ@1117|Cyanobacteria,1H1SY@1129|Synechococcus 1117|Cyanobacteria K Acetyltransferase (GNAT) family - - - - - - - - - - - - Acetyltransf_1 k141_18361_1 223926.28808920 9.62e-157 444.0 COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,1RN5G@1236|Gammaproteobacteria,1XSEP@135623|Vibrionales 135623|Vibrionales S ATPase family associated with various cellular activities (AAA) - - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 k141_18361_2 223926.28808921 4.84e-209 580.0 COG1721@1|root,COG1721@2|Bacteria,1R7RH@1224|Proteobacteria,1S0N5@1236|Gammaproteobacteria,1XTFV@135623|Vibrionales 135623|Vibrionales S Protein of unknown function DUF58 - - - - - - - - - - - - DUF58 k141_18361_3 1116375.VEJY3_19051 3.59e-82 248.0 2C2HX@1|root,338HW@2|Bacteria,1NFY9@1224|Proteobacteria,1SE8S@1236|Gammaproteobacteria,1XXPW@135623|Vibrionales 135623|Vibrionales S Domain of unknown function (DUF4381) - - - - - - - - - - - - DUF4381 k141_18361_4 1219076.N646_4126 7.96e-217 603.0 COG2304@1|root,COG2304@2|Bacteria,1MXQ7@1224|Proteobacteria,1RNRU@1236|Gammaproteobacteria,1XU1F@135623|Vibrionales 135623|Vibrionales S von Willebrand factor type A domain - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - VWA k141_18361_5 1116375.VEJY3_19061 0.0 947.0 COG2304@1|root,COG2304@2|Bacteria,1MW51@1224|Proteobacteria,1RY2E@1236|Gammaproteobacteria,1XTIV@135623|Vibrionales 135623|Vibrionales S von Willebrand factor type A domain - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - VWA_2 k141_18361_6 223926.28808925 9.08e-229 640.0 2B49U@1|root,31X13@2|Bacteria,1QUH7@1224|Proteobacteria,1S7FB@1236|Gammaproteobacteria,1XTIX@135623|Vibrionales 135623|Vibrionales S Oxygen tolerance - - - - - - - - - - - - BatD k141_8833_1 1121104.AQXH01000003_gene329 1.32e-46 169.0 COG5276@1|root,COG5276@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Big_2,DUF1566,LVIVD,Pec_lyase_C,Pectinesterase k141_595_1 1279017.AQYJ01000021_gene2857 1.58e-251 712.0 COG1472@1|root,COG1472@2|Bacteria,1MVIV@1224|Proteobacteria,1RMA0@1236|Gammaproteobacteria,465BV@72275|Alteromonadaceae 1236|Gammaproteobacteria G Family 3 - - 3.2.1.21 ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 - R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - GH3 - Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C,Lipase_GDSL_2 k141_26812_1 1504981.KO116_1804 1.04e-38 129.0 COG0636@1|root,32S3K@2|Bacteria,1N1NA@1224|Proteobacteria,1S9MD@1236|Gammaproteobacteria,1XM2I@135619|Oceanospirillales 135619|Oceanospirillales C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpE - - ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_C k141_26812_2 42565.FP66_02550 4.38e-86 259.0 COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,1RPHK@1236|Gammaproteobacteria,1XH68@135619|Oceanospirillales 135619|Oceanospirillales C it plays a direct role in the translocation of protons across the membrane atpB - - ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 - - ATP-synt_A k141_11199_1 1279017.AQYJ01000026_gene359 1.41e-176 505.0 COG0642@1|root,COG2205@2|Bacteria,1N17V@1224|Proteobacteria,1T1JX@1236|Gammaproteobacteria,466X6@72275|Alteromonadaceae 1236|Gammaproteobacteria T Signal transduction histidine kinase cpxA - 2.7.13.3 ko:K07640 ko01503,ko02020,map01503,map02020 M00447,M00727,M00728 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA k141_11199_2 1279017.AQYJ01000026_gene360 7.55e-44 149.0 COG3832@1|root,COG3832@2|Bacteria,1RDMX@1224|Proteobacteria,1S914@1236|Gammaproteobacteria,46DJU@72275|Alteromonadaceae 1236|Gammaproteobacteria S Polyketide cyclase / dehydrase and lipid transport - - - - - - - - - - - - GyrI-like,Polyketide_cyc2 k141_13671_1 1453501.JELR01000001_gene2871 2.16e-134 388.0 COG0560@1|root,COG0560@2|Bacteria,1MW38@1224|Proteobacteria,1RQAT@1236|Gammaproteobacteria,464CR@72275|Alteromonadaceae 1236|Gammaproteobacteria E haloacid dehalogenase-like hydrolase - - - - - - - - - - - - HAD k141_20617_1 1537994.JQFW01000022_gene132 8.23e-58 201.0 COG4774@1|root,COG4774@2|Bacteria,1R2NB@1224|Proteobacteria 1224|Proteobacteria P TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_27649_1 247490.KSU1_C1435 5.53e-43 156.0 COG1752@1|root,COG1752@2|Bacteria,2J4RT@203682|Planctomycetes 203682|Planctomycetes S Patatin-like phospholipase - - - ko:K07001 - - - - ko00000 - - - Patatin k141_5244_1 218284.CCDN010000007_gene3957 8.78e-123 358.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HA2A@91061|Bacilli,1ZBG3@1386|Bacillus 91061|Bacilli I acyl-CoA dehydrogenase mmgC - - ko:K18244 - - - - ko00000,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_12513_1 1294265.JCM21738_2009 6.25e-128 366.0 COG1013@1|root,COG1013@2|Bacteria,1UZ67@1239|Firmicutes,4IK6N@91061|Bacilli,1ZFE8@1386|Bacillus 91061|Bacilli C Thiamine pyrophosphate enzyme, C-terminal TPP binding domain - - - - - - - - - - - - TPP_enzyme_C k141_11200_1 1279017.AQYJ01000011_gene3050 1.57e-14 73.6 COG1521@1|root,COG1521@2|Bacteria,1MUYA@1224|Proteobacteria,1S99V@1236|Gammaproteobacteria,467TT@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis coaX - 2.7.1.33 ko:K03525 ko00770,ko01100,map00770,map01100 M00120 R02971,R03018,R04391 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Pan_kinase k141_11200_2 1042377.AFPJ01000004_gene414 2.06e-23 98.2 COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1MWCC@1224|Proteobacteria,1RNGC@1236|Gammaproteobacteria,465FU@72275|Alteromonadaceae 1236|Gammaproteobacteria K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon birA GO:0000166,GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004077,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009305,GO:0009374,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0017053,GO:0017076,GO:0017144,GO:0018130,GO:0018271,GO:0019538,GO:0019752,GO:0019842,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032991,GO:0033218,GO:0033293,GO:0034641,GO:0035639,GO:0036094,GO:0036211,GO:0042364,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043565,GO:0043603,GO:0043604,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681,GO:1990837 6.3.4.15 ko:K03524 ko00780,ko01100,map00780,map01100 - R01074,R05145 RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko01000,ko03000 - - - BPL_C,BPL_LplA_LipB,HTH_11 k141_18362_1 218284.CCDN010000002_gene2855 1.13e-138 430.0 COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1TQ0B@1239|Firmicutes,4HA4G@91061|Bacilli,1ZBFF@1386|Bacillus 91061|Bacilli E glutamate synthase gltA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14,1.4.7.1 ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 - R00021,R00093,R00114,R00248,R10086 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - GATase_2,GXGXG,Glu_syn_central,Glu_synthase k141_26813_1 1294265.JCM21738_2495 1.4e-35 121.0 28H8D@1|root,2Z7KA@2|Bacteria,1UB21@1239|Firmicutes,4HA47@91061|Bacilli,1ZB3G@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_31322_1 523791.Kkor_0387 9.64e-54 181.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,1XHE8@135619|Oceanospirillales 135619|Oceanospirillales C belongs to the aldehyde dehydrogenase family - - 1.2.1.32,1.2.1.60,1.2.1.8,1.2.1.85 ko:K00130,ko:K00151,ko:K10217 ko00260,ko00350,ko00362,ko00380,ko00622,ko01100,ko01120,ko01220,map00260,map00350,map00362,map00380,map00622,map01100,map01120,map01220 M00038,M00533,M00555,M00569 R02565,R02566,R02762,R03889,R04418,R05353 RC00080,RC00218,RC00254 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_31322_2 1237149.C900_04977 3.55e-74 224.0 COG0251@1|root,COG0251@2|Bacteria,4NMHF@976|Bacteroidetes,47PT2@768503|Cytophagia 976|Bacteroidetes J Endoribonuclease L-PSP - - 3.5.99.5 ko:K15067 ko00380,map00380 - R03887 RC01015 ko00000,ko00001,ko01000 - - - Ribonuc_L-PSP k141_4097_1 1453501.JELR01000002_gene881 9.14e-107 308.0 COG3034@1|root,COG3034@2|Bacteria,1MXY6@1224|Proteobacteria,1S66I@1236|Gammaproteobacteria,4682Y@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria IV02_27405 - - - - - - - - - - - YkuD k141_34915_1 1405.DJ92_2955 2.48e-66 218.0 COG0671@1|root,COG0671@2|Bacteria,1USD9@1239|Firmicutes,4HAYV@91061|Bacilli,1ZDCF@1386|Bacillus 91061|Bacilli I PAP2 superfamily - - - - - - - - - - - - PAP2 k141_28971_1 4113.PGSC0003DMT400022924 1.98e-07 57.8 COG3320@1|root,KOG1221@2759|Eukaryota,37ZG6@33090|Viridiplantae,3GNJD@35493|Streptophyta,44QI5@71274|asterids 35493|Streptophyta I Catalyzes the reduction of fatty acyl-CoA to fatty alcohols - - 1.2.1.84 ko:K13356 ko00073,ko04146,ko04212,map00073,map04146,map04212 - R09470 RC00004 ko00000,ko00001,ko01000 - - - NAD_binding_4,Sterile k141_2793_1 574375.BAGA_28820 6.54e-76 242.0 COG0277@1|root,COG0277@2|Bacteria,1UIU4@1239|Firmicutes,4HBGZ@91061|Bacilli,1ZD7D@1386|Bacillus 91061|Bacilli C D-arabinono-1,4-lactone oxidase yitY - - - - - - - - - - - ALO,FAD_binding_4 k141_2793_2 471223.GWCH70_1731 3.48e-22 91.7 COG2271@1|root,COG2271@2|Bacteria,1TT4P@1239|Firmicutes,4HDSQ@91061|Bacilli,1WH6Y@129337|Geobacillus 91061|Bacilli G Major Facilitator Superfamily yitZ GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - MFS_1 k141_13672_1 218284.CCDN010000001_gene6 1.46e-183 529.0 COG0550@1|root,COG0550@2|Bacteria,1TPUS@1239|Firmicutes,4HA6C@91061|Bacilli,1ZB7D@1386|Bacillus 91061|Bacilli L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topA - 5.99.1.2 ko:K03168 - - - - ko00000,ko01000,ko03032,ko03400 - - - Topoisom_bac,Toprim,zf-C4_Topoisom k141_12514_1 218284.CCDN010000001_gene606 6.44e-75 235.0 COG1388@1|root,COG1388@2|Bacteria,1U052@1239|Firmicutes,4HF2C@91061|Bacilli,1ZB2H@1386|Bacillus 91061|Bacilli M stage VI sporulation protein D spoVID GO:0003674,GO:0005488,GO:0005515,GO:0019899,GO:0051117 - ko:K06417 - - - - ko00000 - - - LysM k141_33796_1 717605.Theco_3756 4.46e-64 215.0 COG1195@1|root,COG1195@2|Bacteria,1TP9U@1239|Firmicutes,4HA0W@91061|Bacilli,26QB9@186822|Paenibacillaceae 91061|Bacilli L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP recF GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - ko:K03629 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - SMC_N k141_597_1 1118153.MOY_14017 3.09e-54 189.0 COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,1RNBF@1236|Gammaproteobacteria,1XHJZ@135619|Oceanospirillales 135619|Oceanospirillales J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction pnp - 2.7.7.8 ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 M00394 R00437,R00438,R00439,R00440 RC02795 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 - - - KH_1,PNPase,RNase_PH,RNase_PH_C,S1 k141_19480_2 574376.BAMA_09570 3.65e-35 125.0 COG0778@1|root,COG0778@2|Bacteria,1UXYI@1239|Firmicutes,4HBMN@91061|Bacilli,1ZQ88@1386|Bacillus 91061|Bacilli C nitroreductase yodC - - - - - - - - - - - Nitroreductase k141_13673_1 102129.Lepto7375DRAFT_0219 6.72e-30 120.0 COG1680@1|root,COG1680@2|Bacteria,1G7C0@1117|Cyanobacteria,1HD9W@1150|Oscillatoriales 1117|Cyanobacteria V Beta-lactamase - - 3.4.16.4 ko:K01286 - - - - ko00000,ko01000 - - - Beta-lactamase k141_21851_1 1294265.JCM21738_2503 1.74e-121 350.0 COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,4HA31@91061|Bacilli,1ZB6P@1386|Bacillus 91061|Bacilli O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain htrA - 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Trypsin_2 k141_28972_1 218284.CCDN010000001_gene1283 5.79e-95 286.0 COG0547@1|root,COG0547@2|Bacteria,1TP8U@1239|Firmicutes,4H9KQ@91061|Bacilli,1ZBZ1@1386|Bacillus 91061|Bacilli E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) trpD GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0004425,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R00985,R00986,R01073 RC00010,RC00440,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Glycos_trans_3N,Glycos_transf_3 k141_31323_1 218284.CCDN010000001_gene110 1.28e-78 250.0 2D69E@1|root,32TKR@2|Bacteria,1VCRS@1239|Firmicutes,4HMFA@91061|Bacilli,1ZAXR@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - Cu_amine_oxidN1 k141_30068_1 218284.CCDN010000001_gene987 2.65e-132 385.0 COG0508@1|root,COG0508@2|Bacteria,1TQSH@1239|Firmicutes,4HBSU@91061|Bacilli,1ZC6F@1386|Bacillus 91061|Bacilli C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex bkdB - 2.3.1.12,2.3.1.168 ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 M00036,M00307 R00209,R02569,R02662,R03174,R04097,R10998 RC00004,RC02727,RC02742,RC02857,RC02870 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding k141_18364_2 1449350.OCH239_08050 8.91e-09 57.8 COG3439@1|root,COG3439@2|Bacteria,1MZ38@1224|Proteobacteria,2UBVK@28211|Alphaproteobacteria,4KNVQ@93682|Roseivivax 28211|Alphaproteobacteria S Domain of unknown function DUF302 ccrB - - - - - - - - - - - DUF302 k141_7545_1 1453501.JELR01000002_gene59 4.76e-230 647.0 COG0365@1|root,COG0365@2|Bacteria,1MUX7@1224|Proteobacteria,1RPGT@1236|Gammaproteobacteria,465WE@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases acsA - 6.2.1.16 ko:K01907 ko00280,ko00650,map00280,map00650 - R01357 RC00004,RC00014 ko00000,ko00001,ko01000,ko01004 - - - ACAS_N,AMP-binding,AMP-binding_C k141_7545_2 1453501.JELR01000002_gene57 3.49e-68 208.0 2DHXS@1|root,32U9Z@2|Bacteria,1N3G8@1224|Proteobacteria,1SASY@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_26815_1 1042377.AFPJ01000042_gene1015 1.11e-174 506.0 COG1472@1|root,COG1472@2|Bacteria,1MVAJ@1224|Proteobacteria,1RMQF@1236|Gammaproteobacteria,465G4@72275|Alteromonadaceae 1236|Gammaproteobacteria G Beta-N-acetylhexosaminidase ybbD - 3.2.1.52 ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 M00628 R00022,R05963,R07809,R07810,R10831 RC00049 ko00000,ko00001,ko00002,ko01000 - - - Glyco_hydro_3,Glyco_hydro_3_C k141_599_1 218284.CCDN010000001_gene1912 5.03e-101 311.0 COG1298@1|root,COG1298@2|Bacteria,1TQBM@1239|Firmicutes,4H9XU@91061|Bacilli,1ZBID@1386|Bacillus 91061|Bacilli N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin flhA - - ko:K02400 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 - - FHIPEP k141_8836_1 218284.CCDN010000007_gene3861 1.2e-115 358.0 COG1511@1|root,COG1511@2|Bacteria,1UZD1@1239|Firmicutes,4HEK8@91061|Bacilli,1ZC64@1386|Bacillus 91061|Bacilli S domain protein yueB - - - - - - - - - - - ABC2_membrane_3 k141_20619_1 1096546.WYO_2913 1.6e-38 141.0 COG1597@1|root,COG1597@2|Bacteria,1MY37@1224|Proteobacteria,2TT5I@28211|Alphaproteobacteria,1JS9H@119045|Methylobacteriaceae 28211|Alphaproteobacteria I PFAM Diacylglycerol kinase catalytic - - - - - - - - - - - - DAGK_cat k141_17074_1 1280001.BAOA01000031_gene5148 1.55e-200 572.0 COG0840@1|root,COG0840@2|Bacteria,1RIXH@1224|Proteobacteria,1S7AG@1236|Gammaproteobacteria,1XTSE@135623|Vibrionales 135623|Vibrionales NT COG0840 Methyl-accepting chemotaxis protein - - - - - - - - - - - - MCPsignal k141_17074_2 1116375.VEJY3_04885 7.19e-135 383.0 COG0632@1|root,COG0632@2|Bacteria,1MWJR@1224|Proteobacteria,1RMET@1236|Gammaproteobacteria,1XSGY@135623|Vibrionales 135623|Vibrionales L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB ruvA GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0006139,GO:0006259,GO:0006310,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009378,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 3.6.4.12 ko:K03550 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - HHH_5,RuvA_C,RuvA_N k141_17074_3 1219076.N646_0113 9.5e-235 647.0 COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,1RNWY@1236|Gammaproteobacteria,1XV8V@135623|Vibrionales 135623|Vibrionales L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing ruvB GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0006139,GO:0006259,GO:0006310,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009378,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 3.6.4.12 ko:K03551 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvB_C,RuvB_N k141_17074_4 1280001.BAOA01000031_gene5151 4.61e-161 463.0 COG1271@1|root,COG1271@2|Bacteria,1MV60@1224|Proteobacteria,1RN2U@1236|Gammaproteobacteria,1XT5F@135623|Vibrionales 135623|Vibrionales C COG1271 Cytochrome bd-type quinol oxidase, subunit 1 cydA - 1.10.3.14 ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - Cyt_bd_oxida_I k141_11204_1 55601.VANGNB10_cI1046c 8.53e-83 262.0 COG2985@1|root,COG3273@1|root,COG2985@2|Bacteria,COG3273@2|Bacteria,1MUVM@1224|Proteobacteria,1RQ47@1236|Gammaproteobacteria,1XSX8@135623|Vibrionales 135623|Vibrionales P transport protein ybjL - - ko:K07085 - - - - ko00000 2.A.81 - - Asp-Al_Ex,TrkA_C k141_12517_1 218284.CCDN010000001_gene1173 1.84e-118 370.0 COG0699@1|root,COG0699@2|Bacteria,1TR0Q@1239|Firmicutes,4HBAC@91061|Bacilli,1ZAXM@1386|Bacillus 91061|Bacilli S Dynamin family ypbR GO:0000910,GO:0003674,GO:0003824,GO:0003924,GO:0005575,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022402,GO:0022607,GO:0031224,GO:0032506,GO:0044085,GO:0044425,GO:0051301,GO:0071840,GO:0090529 - - - - - - - - - - Dynamin_N k141_21871_1 218284.CCDN010000002_gene2004 1.12e-109 323.0 COG0002@1|root,COG0002@2|Bacteria,1TPVI@1239|Firmicutes,4H9YD@91061|Bacilli,1ZBHP@1386|Bacillus 91061|Bacilli E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde argC GO:0003674,GO:0003824,GO:0003942,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.38 ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R03443 RC00684 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU11190 Semialdhyde_dh,Semialdhyde_dhC k141_21871_2 218284.CCDN010000002_gene2005 5.39e-15 73.6 COG1364@1|root,COG1364@2|Bacteria,1TPBP@1239|Firmicutes,4H9TQ@91061|Bacilli,1ZAU3@1386|Bacillus 91061|Bacilli E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate argJ GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R00259,R02282 RC00004,RC00064 ko00000,ko00001,ko00002,ko01000 - - - ArgJ k141_34956_1 523791.Kkor_0416 1.19e-19 94.4 COG3866@1|root,COG4932@1|root,COG3866@2|Bacteria,COG4932@2|Bacteria 2|Bacteria M domain protein - - - - - - - - - - - - Pec_lyase_C k141_37247_2 1279017.AQYJ01000028_gene2115 3.71e-53 169.0 2E35S@1|root,32Y5P@2|Bacteria,1N6WS@1224|Proteobacteria,1SD5T@1236|Gammaproteobacteria,468S2@72275|Alteromonadaceae 1236|Gammaproteobacteria S Putative prokaryotic signal transducing protein - - - - - - - - - - - - DUF2007 k141_37247_3 323261.Noc_0087 3.31e-95 285.0 COG2859@1|root,COG2859@2|Bacteria,1QU0K@1224|Proteobacteria,1RR22@1236|Gammaproteobacteria,1WYZ2@135613|Chromatiales 135613|Chromatiales S Protein of unknown function (DUF541) - - - ko:K09797 - - - - ko00000 - - - SIMPL k141_37247_5 1042377.AFPJ01000044_gene642 1.04e-54 174.0 2DMKI@1|root,32S70@2|Bacteria,1N1FV@1224|Proteobacteria,1S778@1236|Gammaproteobacteria,46BB3@72275|Alteromonadaceae 1236|Gammaproteobacteria S SpoIIAA-like VVA0543 - - - - - - - - - - - SpoIIAA-like k141_623_1 1294265.JCM21738_4817 2.85e-154 439.0 COG1135@1|root,COG1135@2|Bacteria,1TPPN@1239|Firmicutes,4H9VX@91061|Bacilli,1ZAZX@1386|Bacillus 91061|Bacilli P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system metN - - ko:K02071 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - ABC_tran,NIL k141_30088_1 443218.AS9A_0318 1.42e-58 201.0 2C593@1|root,2Z84R@2|Bacteria,2I0MZ@201174|Actinobacteria,23D7P@1762|Mycobacteriaceae 201174|Actinobacteria - - - - - - - - - - - - - - - k141_8858_2 1279017.AQYJ01000029_gene3373 7.74e-07 48.1 COG3114@1|root,COG3114@2|Bacteria,1NGBM@1224|Proteobacteria,1SGGH@1236|Gammaproteobacteria,4691H@72275|Alteromonadaceae 1236|Gammaproteobacteria U Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes ccmD GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0009898,GO:0015886,GO:0016020,GO:0031224,GO:0031226,GO:0031235,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051181,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0098552,GO:0098562,GO:1901678 - ko:K02196 ko02010,map02010 - - - ko00000,ko00001,ko02000 3.A.1.107 - iB21_1397.B21_02084,iBWG_1329.BWG_1971,iE2348C_1286.E2348C_2342,iEC042_1314.EC042_2439,iEC55989_1330.EC55989_2451,iECABU_c1320.ECABU_c25320,iECBD_1354.ECBD_1462,iECB_1328.ECB_02125,iECDH10B_1368.ECDH10B_2355,iECDH1ME8569_1439.ECDH1ME8569_2133,iECD_1391.ECD_02125,iECED1_1282.ECED1_2663,iECH74115_1262.ECH74115_3335,iECIAI1_1343.ECIAI1_2280,iECIAI39_1322.ECIAI39_2336,iECNA114_1301.ECNA114_2290,iECO103_1326.ECO103_2673,iECO111_1330.ECO111_2934,iECO26_1355.ECO26_3124,iECOK1_1307.ECOK1_2432,iECP_1309.ECP_2238,iECS88_1305.ECS88_2345,iECSE_1348.ECSE_2466,iECSF_1327.ECSF_2079,iECSP_1301.ECSP_3077,iECUMN_1333.ECUMN_2533,iECs_1301.ECs3087,iEKO11_1354.EKO11_1558,iETEC_1333.ETEC_2332,iEcDH1_1363.EcDH1_1461,iEcE24377_1341.EcE24377A_2497,iEcHS_1320.EcHS_A2336,iEcSMS35_1347.EcSMS35_2346,iEcolC_1368.EcolC_1452,iJO1366.b2198,iLF82_1304.LF82_0276,iNRG857_1313.NRG857_11155,iSDY_1059.SDY_0880,iSFV_1184.SFV_2274,iSF_1195.SF2282,iSSON_1240.SSON_2256,iS_1188.S2412,iUMN146_1321.UM146_05815,iUMNK88_1353.UMNK88_2745,iUTI89_1310.UTI89_C2476,iY75_1357.Y75_RS11500,iZ_1308.Z3455,ic_1306.c2735 CcmD k141_2817_1 1453501.JELR01000006_gene22 2.26e-96 305.0 COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,464SF@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG2217 Cation transport ATPase ccoI - 3.6.3.4 ko:K01533 - - R00086 RC00002 ko00000,ko01000 3.A.3.5 - - ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase k141_15892_1 1116375.VEJY3_18296 3.62e-118 357.0 COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,1RNKA@1236|Gammaproteobacteria 1236|Gammaproteobacteria H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses nadE - 6.3.1.5,6.3.5.1 ko:K01916,ko:K01950 ko00760,ko01100,map00760,map01100 M00115 R00189,R00257 RC00010,RC00100 ko00000,ko00001,ko00002,ko01000 - - - CN_hydrolase,NAD_synthase k141_34957_1 555088.DealDRAFT_1109 4.09e-69 232.0 COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,42JNC@68298|Syntrophomonadaceae 186801|Clostridia O Belongs to the ClpA ClpB family clpC - - ko:K03696 ko01100,map01100 - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N,UVR k141_7560_2 1188252.AJYK01000062_gene1925 8.38e-110 330.0 COG2207@1|root,COG2207@2|Bacteria,1MX23@1224|Proteobacteria,1RRXM@1236|Gammaproteobacteria,1Y2JT@135623|Vibrionales 135623|Vibrionales K Arabinose-binding domain of AraC transcription regulator, N-term - - - - - - - - - - - - Arabinose_bd,HTH_18 k141_7560_3 1042377.AFPJ01000037_gene2918 2.99e-16 79.0 COG3678@1|root,COG3678@2|Bacteria,1RBDH@1224|Proteobacteria,1S2DT@1236|Gammaproteobacteria 1236|Gammaproteobacteria NPTU P pilus assembly Cpx signaling pathway, periplasmic inhibitor zinc-resistance associated protein spy - - - - - - - - - - - LTXXQ k141_7560_4 1123054.KB907704_gene1126 1.77e-75 234.0 COG0500@1|root,COG0500@2|Bacteria,1RAE4@1224|Proteobacteria,1S0RC@1236|Gammaproteobacteria,1WX0X@135613|Chromatiales 135613|Chromatiales Q Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family tpm - 2.1.1.67 ko:K00569 ko00983,map00983 - R08236,R08239,R08246 RC00003,RC00980,RC02277 ko00000,ko00001,ko01000 - - - TPMT k141_7560_5 1265503.KB905175_gene4012 2.57e-72 225.0 2EYIJ@1|root,33RSC@2|Bacteria,1NQWX@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_13694_1 218284.CCDN010000001_gene1368 3.83e-118 345.0 COG0477@1|root,COG2814@2|Bacteria,1UN0M@1239|Firmicutes,4HBBP@91061|Bacilli,1ZD0U@1386|Bacillus 91061|Bacilli EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 k141_31339_1 1453501.JELR01000002_gene323 1.77e-23 97.8 COG3712@1|root,COG3712@2|Bacteria,1MZCK@1224|Proteobacteria,1S88I@1236|Gammaproteobacteria,467V5@72275|Alteromonadaceae 1236|Gammaproteobacteria PT Domain of unknown function (DUF4880) - - - ko:K07165 - - - - ko00000 - - - DUF4880,DUF4974,FecR k141_30089_2 935836.JAEL01000064_gene4567 7.86e-43 142.0 COG0229@1|root,COG0229@2|Bacteria,1UPN0@1239|Firmicutes,4HGWN@91061|Bacilli,1ZFQG@1386|Bacillus 91061|Bacilli O peptide methionine sulfoxide reductase msrB - 1.8.4.12 ko:K07305 - - - - ko00000,ko01000 - - - SelR k141_12555_1 661478.OP10G_0546 4.36e-89 268.0 COG0396@1|root,COG0396@2|Bacteria 2|Bacteria O ATPase activity sufC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0071840 - ko:K09013 - - - - ko00000,ko02000 - - iECH74115_1262.ECH74115_2396,iECIAI1_1343.ECIAI1_1734,iECIAI39_1322.ECIAI39_1376,iECSP_1301.ECSP_2249,iECs_1301.ECs2389,iEcSMS35_1347.EcSMS35_1514,iG2583_1286.G2583_2077,iSFV_1184.SFV_1705,iSFxv_1172.SFxv_1919,iSSON_1240.SSON_1474,iS_1188.S1844,iZ_1308.Z2710 ABC_tran k141_37249_2 867845.KI911784_gene1321 1.72e-18 81.6 2FFVE@1|root,347SF@2|Bacteria,2GB3K@200795|Chloroflexi,377UV@32061|Chloroflexia 32061|Chloroflexia - - - - - - - - - - - - - - - k141_4109_1 218284.CCDN010000001_gene1423 2.34e-15 73.6 COG1011@1|root,COG1011@2|Bacteria,1TS3W@1239|Firmicutes,4HADE@91061|Bacilli,1ZBN8@1386|Bacillus 91061|Bacilli S HAD-hyrolase-like ysaA - 3.1.3.5,3.8.1.2 ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346,R05287 RC00017,RC00697 ko00000,ko00001,ko01000 - - - HAD_2 k141_4109_2 218284.CCDN010000001_gene1422 4.05e-45 147.0 COG4768@1|root,COG4768@2|Bacteria,1UBBB@1239|Firmicutes,4IMQ8@91061|Bacilli,1ZKKT@1386|Bacillus 91061|Bacilli S protein containing a divergent version of the methyl-accepting chemotaxis-like domain - - - - - - - - - - - - DUF948 k141_27669_1 1278308.KB907081_gene2564 6.18e-20 91.7 COG0611@1|root,COG0611@2|Bacteria,2GP6E@201174|Actinobacteria,4FKD1@85023|Microbacteriaceae 201174|Actinobacteria H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 thiL GO:0008150,GO:0040007 2.7.4.16 ko:K00946 ko00730,ko01100,map00730,map01100 M00127 R00617 RC00002 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv2977c AIRS,AIRS_C k141_6476_2 1116375.VEJY3_04760 0.0 880.0 COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,1RNMP@1236|Gammaproteobacteria,1XSTA@135623|Vibrionales 135623|Vibrionales F Synthesizes alpha-1,4-glucan chains using ADP-glucose glgA GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 M00565 R02421 RC00005 ko00000,ko00001,ko00002,ko01000,ko01003 - GT5 - Glyco_transf_5,Glycos_transf_1 k141_6476_3 223926.28806010 9.71e-293 799.0 COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,1RP04@1236|Gammaproteobacteria,1XTGB@135623|Vibrionales 135623|Vibrionales H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans glgC GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008878,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0070566,GO:0071704,GO:1901576 2.7.7.27 ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase k141_20638_1 218284.CCDN010000005_gene3352 4.81e-56 182.0 2BCUG@1|root,326F1@2|Bacteria,1V8P9@1239|Firmicutes,4HYG5@91061|Bacilli,1ZHBA@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_24178_2 1116375.VEJY3_03810 2.04e-120 344.0 COG3057@1|root,COG3057@2|Bacteria,1MUW8@1224|Proteobacteria,1RQ83@1236|Gammaproteobacteria,1XVQ2@135623|Vibrionales 135623|Vibrionales L Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated seqA GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0043565,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1990837,GO:2000112,GO:2000113 - ko:K03645 - - - - ko00000,ko03032,ko03036 - - - SeqA,SeqA_N k141_24178_3 1219076.N646_2991 0.0 1080.0 COG0033@1|root,COG0033@2|Bacteria,1MU5S@1224|Proteobacteria,1RPDV@1236|Gammaproteobacteria,1XT0B@135623|Vibrionales 135623|Vibrionales G Phosphoglucomutase pgm - 5.4.2.2 ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00549 R00959,R01057,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV k141_24178_4 1116375.VEJY3_03820 4.23e-148 420.0 COG3782@1|root,COG3782@2|Bacteria,1N971@1224|Proteobacteria,1SD24@1236|Gammaproteobacteria,1XSBE@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria - - - ko:K09977 - - - - ko00000 - - - DUF1853 k141_24178_5 1116375.VEJY3_03825 3.16e-180 501.0 COG0327@1|root,COG0327@2|Bacteria,1MVUN@1224|Proteobacteria,1RNBU@1236|Gammaproteobacteria,1XUIZ@135623|Vibrionales 135623|Vibrionales S NIF3 (NGG1p interacting factor 3) ybgI GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - - - - - - - - - - NIF3 k141_24178_6 1116375.VEJY3_03830 0.0 872.0 COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,1RNDK@1236|Gammaproteobacteria,1XSCA@135623|Vibrionales 135623|Vibrionales C Belongs to the citrate synthase family gltA - 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 - - - Citrate_synt k141_24178_7 1219076.N646_2995 7.11e-81 240.0 COG2009@1|root,COG2009@2|Bacteria,1RIGZ@1224|Proteobacteria,1S5ZE@1236|Gammaproteobacteria,1XXGA@135623|Vibrionales 135623|Vibrionales C COG2009 Succinate dehydrogenase fumarate reductase, cytochrome b subunit sdhC - - ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002 - - - Sdh_cyt k141_4292_3 1123070.KB899249_gene349 8.31e-121 369.0 COG1574@1|root,COG1574@2|Bacteria,46V0N@74201|Verrucomicrobia,2IVDG@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Amidohydrolase family - - - - - - - - - - - - Amidohydro_3 k141_24555_1 1453501.JELR01000002_gene1529 1.64e-85 263.0 COG3135@1|root,COG3135@2|Bacteria,1MUS1@1224|Proteobacteria,1RMD5@1236|Gammaproteobacteria,4660J@72275|Alteromonadaceae 1236|Gammaproteobacteria Q protein involved in benzoate metabolism benE - - ko:K05782 - - - - ko00000,ko02000 2.A.46.1 - - BenE k141_12818_1 1453501.JELR01000002_gene1108 1.27e-74 249.0 COG1404@1|root,COG1404@2|Bacteria,1MVJE@1224|Proteobacteria,1RQ2M@1236|Gammaproteobacteria,4683H@72275|Alteromonadaceae 1236|Gammaproteobacteria O Peptidase inhibitor I9 - - - - - - - - - - - - Inhibitor_I9,PA,Peptidase_S8 k141_10383_1 218284.CCDN010000004_gene3156 5.15e-87 263.0 COG0561@1|root,COG0561@2|Bacteria,1V2XI@1239|Firmicutes,4HG2U@91061|Bacilli,1ZB1F@1386|Bacillus 91061|Bacilli S hydrolases of the HAD superfamily yhaX - - - - - - - - - - - Hydrolase_3 k141_35303_1 218284.CCDN010000007_gene3971 1.41e-188 531.0 COG0766@1|root,COG0766@2|Bacteria,1TPAU@1239|Firmicutes,4H9KI@91061|Bacilli,1ZASB@1386|Bacillus 91061|Bacilli M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine murA GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008760,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042221,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0070589,GO:0070887,GO:0071236,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R00660 RC00350 ko00000,ko00001,ko01000,ko01011 - - iYO844.BSU37100 EPSP_synthase k141_6740_1 1116375.VEJY3_07590 1.19e-128 365.0 28I7M@1|root,2Z8AH@2|Bacteria,1N1DT@1224|Proteobacteria,1RYK3@1236|Gammaproteobacteria,1XVKE@135623|Vibrionales 135623|Vibrionales D Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ zapC - - ko:K18657 - - - - ko00000,ko03036 - - - ZapC k141_6740_2 223926.28806591 1.11e-238 656.0 COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,1RMCP@1236|Gammaproteobacteria,1XU4H@135623|Vibrionales 135623|Vibrionales F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor pyrD GO:0003674,GO:0003824,GO:0004152,GO:0004158,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016634,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.5.2 ko:K00254 ko00240,ko01100,map00240,map01100 M00051 R01868 RC00051 ko00000,ko00001,ko00002,ko01000 - - - DHO_dh k141_6740_3 1116375.VEJY3_07600 0.0 3006.0 COG2902@1|root,COG2902@2|Bacteria,1MXNV@1224|Proteobacteria,1RQVZ@1236|Gammaproteobacteria,1XUBT@135623|Vibrionales 135623|Vibrionales E NAD-specific glutamate dehydrogenase gdhB - 1.4.1.2 ko:K15371 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 - R00243 RC00006,RC02799 ko00000,ko00001,ko01000 - - - Bac_GDH k141_6740_4 1116375.VEJY3_07610 0.0 1648.0 COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,1RMA7@1236|Gammaproteobacteria,1XUSZ@135623|Vibrionales 135623|Vibrionales E COG0308 Aminopeptidase N pepN - 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - DUF3458,DUF3458_C,Peptidase_M1 k141_6740_5 1116375.VEJY3_07615 4.47e-149 420.0 2AM7R@1|root,31C2D@2|Bacteria,1QJDQ@1224|Proteobacteria,1THCV@1236|Gammaproteobacteria,1XU2R@135623|Vibrionales 135623|Vibrionales - - VP1605 - - - - - - - - - - - - k141_6740_6 1116375.VEJY3_07620 0.0 1205.0 COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,1RMSR@1236|Gammaproteobacteria,1XT5Z@135623|Vibrionales 135623|Vibrionales M protease prc - 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - BAGE,DUF3340,PDZ,Peptidase_S41 k141_6740_7 674977.VMC_30650 5.75e-128 367.0 COG3109@1|root,COG3109@2|Bacteria,1N68T@1224|Proteobacteria,1RP4S@1236|Gammaproteobacteria,1XT78@135623|Vibrionales 135623|Vibrionales J RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities proQ - - ko:K03607 - - - - ko00000 - - - ProQ,ProQ_C k141_6740_8 223926.28806599 7.43e-105 303.0 COG1956@1|root,COG1956@2|Bacteria,1RDBM@1224|Proteobacteria,1S6QU@1236|Gammaproteobacteria,1XX5M@135623|Vibrionales 135623|Vibrionales T GAF domain-containing protein yebR - 1.8.4.14 ko:K08968 ko00270,map00270 - R02025 RC00639 ko00000,ko00001,ko01000 - - - GAF_2 k141_6740_9 1116375.VEJY3_07635 0.0 1068.0 COG1132@1|root,COG1132@2|Bacteria,1N1Z8@1224|Proteobacteria,1RPVC@1236|Gammaproteobacteria,1XTG4@135623|Vibrionales 135623|Vibrionales V COG1132 ABC-type multidrug transport system, ATPase and permease components ygaD - - ko:K06147,ko:K06148 - - - - ko00000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran k141_6740_10 1116375.VEJY3_07640 9.87e-282 772.0 COG2995@1|root,COG2995@2|Bacteria,1MWG1@1224|Proteobacteria,1RM9Z@1236|Gammaproteobacteria,1XT4U@135623|Vibrionales 135623|Vibrionales S paraquat-inducible protein A - - - ko:K03808 - - - - ko00000 - - - PqiA k141_6740_11 1116375.VEJY3_07645 0.0 1579.0 COG3008@1|root,COG3008@2|Bacteria,1MU1T@1224|Proteobacteria,1RN89@1236|Gammaproteobacteria,1XTE9@135623|Vibrionales 135623|Vibrionales Q Paraquat-inducible protein B - - - - - - - - - - - - MlaD k141_14065_2 218284.CCDN010000002_gene2088 3.83e-65 198.0 COG3224@1|root,COG3224@2|Bacteria,1V83H@1239|Firmicutes,4HJC6@91061|Bacilli,1ZHQD@1386|Bacillus 91061|Bacilli S EthD domain ethD - - - - - - - - - - - EthD k141_11588_1 218284.CCDN010000001_gene1859 7.94e-134 386.0 COG1426@1|root,COG1426@2|Bacteria,1V1N7@1239|Firmicutes,4HKW3@91061|Bacilli,1ZDC1@1386|Bacillus 91061|Bacilli S protein conserved in bacteria ymfM - - ko:K15539 - - - - ko00000 - - - DUF4115,HTH_25 k141_29235_1 218284.CCDN010000007_gene3907 8.31e-16 77.8 COG3852@1|root,COG3852@2|Bacteria,1TRH0@1239|Firmicutes,4HD4A@91061|Bacilli,1ZARI@1386|Bacillus 91061|Bacilli T COG0642 Signal transduction histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,PAS,PAS_4,PAS_9 k141_5643_1 218284.CCDN010000001_gene1711 4.53e-95 285.0 COG0640@1|root,COG0640@2|Bacteria,1TSRQ@1239|Firmicutes,4HBXM@91061|Bacilli,1ZD50@1386|Bacillus 91061|Bacilli K ArsR family transcriptional regulator - - - - - - - - - - - - HTH_20,HTH_5 k141_14944_2 1385513.N780_07220 1e-21 87.0 29QW1@1|root,32RMW@2|Bacteria,1VDH7@1239|Firmicutes,4HM2X@91061|Bacilli 91061|Bacilli S Helix-turn-helix domain - - - - - - - - - - - - HTH_16 k141_1830_1 1454202.PPBDW_120198___1 2.05e-12 62.8 2DP07@1|root,3300A@2|Bacteria,1N90I@1224|Proteobacteria,1SFUI@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_32729_1 1123257.AUFV01000007_gene289 2.46e-18 85.9 COG0611@1|root,COG0611@2|Bacteria,1MU9X@1224|Proteobacteria,1RNHU@1236|Gammaproteobacteria,1X3WP@135614|Xanthomonadales 135614|Xanthomonadales H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 thiL - 2.7.4.16 ko:K00946 ko00730,ko01100,map00730,map01100 M00127 R00617 RC00002 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C k141_32729_2 1279017.AQYJ01000028_gene2397 1.61e-21 88.2 COG1267@1|root,COG1267@2|Bacteria,1MZJA@1224|Proteobacteria,1S68A@1236|Gammaproteobacteria,467H1@72275|Alteromonadaceae 1236|Gammaproteobacteria I Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) pgpA GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008962,GO:0009058,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0030258,GO:0031224,GO:0031226,GO:0032026,GO:0042221,GO:0042577,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0046839,GO:0050896,GO:0071704,GO:0071944,GO:0090407,GO:1901576 3.1.3.27 ko:K01095 ko00564,ko01100,map00564,map01100 - R02029 RC00017 ko00000,ko00001,ko01000 - - iECSP_1301.ECSP_0485,iECUMN_1333.ECUMN_0456,iECs_1301.ECs0471,iG2583_1286.G2583_0529,iPC815.YPO3179,iZ_1308.Z0520 PgpA k141_6741_1 1097668.BYI23_A013070 1.37e-47 160.0 COG3571@1|root,COG3571@2|Bacteria,1RD20@1224|Proteobacteria,2VRRK@28216|Betaproteobacteria,1K14S@119060|Burkholderiaceae 28216|Betaproteobacteria S Hydrolase of the alpha beta-hydrolase fold - - - ko:K07020 - - - - ko00000 - - - DLH k141_6741_2 743722.Sph21_3802 1.1e-17 80.9 COG1801@1|root,COG1801@2|Bacteria,4NI47@976|Bacteroidetes,1IPS2@117747|Sphingobacteriia 976|Bacteroidetes S Protein of unknown function DUF72 - - - - - - - - - - - - DUF72 k141_23474_1 1042377.AFPJ01000055_gene1004 1.04e-58 182.0 COG0089@1|root,COG0089@2|Bacteria,1MZXX@1224|Proteobacteria,1S8VX@1236|Gammaproteobacteria,467ZX@72275|Alteromonadaceae 1236|Gammaproteobacteria J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome rplW GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02892 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L23 k141_23474_2 1279017.AQYJ01000019_gene1451 8.67e-189 525.0 COG0090@1|root,COG0090@2|Bacteria,1MVTD@1224|Proteobacteria,1RMGR@1236|Gammaproteobacteria,464EJ@72275|Alteromonadaceae 1236|Gammaproteobacteria J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity rplB GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02886 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L2,Ribosomal_L2_C k141_18759_1 1122135.KB893134_gene3128 3.85e-74 234.0 COG1960@1|root,COG1960@2|Bacteria,1MUTN@1224|Proteobacteria,2U38F@28211|Alphaproteobacteria 28211|Alphaproteobacteria I Acyl-CoA dehydrogenase, C-terminal domain - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_24556_1 218284.CCDN010000008_gene4251 3.95e-41 154.0 COG2199@1|root,COG2203@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,1TQ2X@1239|Firmicutes,4HA6T@91061|Bacilli,1ZCE7@1386|Bacillus 91061|Bacilli T COG2199 FOG GGDEF domain ytrP - - - - - - - - - - - GAF_2,GAF_3,GGDEF k141_19795_1 1174504.AJTN02000257_gene1510 1.85e-29 121.0 COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,4H9T3@91061|Bacilli,1ZCIC@1386|Bacillus 91061|Bacilli L DNA polymerase dnaE - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon k141_19795_2 218284.CCDN010000001_gene509 8.9e-51 171.0 COG0281@1|root,COG0281@2|Bacteria,1TPJ3@1239|Firmicutes,4H9WR@91061|Bacilli,1ZBAH@1386|Bacillus 91061|Bacilli C Malate dehydrogenase ytsJ - 1.1.1.38 ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 - R00214 RC00105 ko00000,ko00001,ko01000 - - - Malic_M,malic k141_1851_1 1307436.PBF_15674 2.65e-17 73.6 29S7X@1|root,30DCE@2|Bacteria,1UB4X@1239|Firmicutes,4IMHG@91061|Bacilli,1ZK60@1386|Bacillus 91061|Bacilli S Sporulation inhibitor A - - - - - - - - - - - - Sda k141_18793_1 218284.CCDN010000001_gene1242 9.69e-73 224.0 COG2340@1|root,COG2340@2|Bacteria,1V6GZ@1239|Firmicutes,4HJ21@91061|Bacilli,1ZDSK@1386|Bacillus 91061|Bacilli J protein with SCP PR1 domains ykwD - - - - - - - - - - - CAP k141_20886_1 218284.CCDN010000002_gene2492 2.66e-82 255.0 COG1593@1|root,COG1593@2|Bacteria,1TPNU@1239|Firmicutes,4H9WK@91061|Bacilli,1ZC02@1386|Bacillus 91061|Bacilli G COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - - - - - - - - - - DctM k141_24592_1 1116375.VEJY3_21711 3.58e-54 180.0 COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,1RMVU@1236|Gammaproteobacteria,1XZTY@135623|Vibrionales 135623|Vibrionales C alcohol dehydrogenase - - - - - - - - - - - - Fe-ADH k141_24592_2 1116375.VEJY3_02905 2.78e-87 262.0 COG0235@1|root,COG0235@2|Bacteria,1MXV2@1224|Proteobacteria,1RP50@1236|Gammaproteobacteria,1XWCD@135623|Vibrionales 135623|Vibrionales G Rhamnulose-1-phosphate aldolase - - 4.1.2.19 ko:K01629 ko00040,ko00051,ko01120,map00040,map00051,map01120 - R01785,R02263 RC00438,RC00599,RC00603,RC00604 ko00000,ko00001,ko01000 - - - Aldolase_II k141_5674_1 218284.CCDN010000002_gene2745 8.37e-72 224.0 28PJY@1|root,2ZC9F@2|Bacteria,1V390@1239|Firmicutes,4HG7F@91061|Bacilli,1ZDN7@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF1836) ykrK - - - - - - - - - - - DUF1836 k141_12839_1 218284.CCDN010000005_gene3319 4.62e-85 253.0 COG1514@1|root,COG1514@2|Bacteria,1V2F3@1239|Firmicutes,4HG6P@91061|Bacilli,1ZG9R@1386|Bacillus 91061|Bacilli J Belongs to the 2H phosphoesterase superfamily. YjcG family yjcG - - - - - - - - - - - 2_5_RNA_ligase2 k141_22186_1 1042377.AFPJ01000021_gene2117 2.66e-39 146.0 COG2244@1|root,COG2244@2|Bacteria 2|Bacteria S polysaccharide biosynthetic process - - - - - - - - - - - - MatE,Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C k141_22186_2 1957.JODX01000007_gene2062 3.13e-102 323.0 COG1804@1|root,COG1804@2|Bacteria,2GKDI@201174|Actinobacteria 201174|Actinobacteria C L-carnitine dehydratase bile acid-inducible protein F - - - - - - - - - - - - CoA_transf_3 k141_23521_1 1453501.JELR01000002_gene342 1.78e-74 258.0 COG1361@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4932@2|Bacteria,1R5G4@1224|Proteobacteria,1SEWA@1236|Gammaproteobacteria,469S7@72275|Alteromonadaceae 1236|Gammaproteobacteria M Domain of unknown function DUF11 - - - - - - - - - - - - DUF11,SdrD_B k141_27201_1 218284.CCDN010000001_gene1313 2.15e-81 245.0 COG1309@1|root,COG1309@2|Bacteria,1VFD2@1239|Firmicutes,4HM3Q@91061|Bacilli,1ZIA5@1386|Bacillus 91061|Bacilli K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N k141_27201_2 218284.CCDN010000001_gene1312 1.65e-67 205.0 COG2076@1|root,COG2076@2|Bacteria,1VA2G@1239|Firmicutes,4HKGV@91061|Bacilli,1ZHW4@1386|Bacillus 91061|Bacilli P Multidrug resistance protein ykkC - - ko:K11741,ko:K18924 - M00712 - - ko00000,ko00002,ko02000 2.A.7.1,2.A.7.1.5 - - Multi_Drug_Res k141_36263_1 398512.JQKC01000082_gene1305 3.66e-79 249.0 COG2357@1|root,COG2357@2|Bacteria,1UZIX@1239|Firmicutes,249PC@186801|Clostridia 186801|Clostridia S Psort location Cytoplasmic, score - - - - - - - - - - - - RelA_SpoT k141_16199_1 218284.CCDN010000001_gene1516 1.67e-73 234.0 COG1292@1|root,COG1292@2|Bacteria,1TRS6@1239|Firmicutes,4HA7U@91061|Bacilli,1ZBRN@1386|Bacillus 91061|Bacilli M Belongs to the BCCT transporter (TC 2.A.15) family opuD GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0016020,GO:0031460,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0072337 - ko:K05020 - - - - ko00000,ko02000 2.A.15.1.1,2.A.15.1.11 - iYO844.BSU30070 BCCT k141_30308_1 1116375.VEJY3_12335 1.78e-123 373.0 COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,1RPA0@1236|Gammaproteobacteria,1XTSQ@135623|Vibrionales 135623|Vibrionales L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD recD - 3.1.11.5 ko:K03581 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_30,UvrD_C_2 k141_6774_1 1280948.HY36_05775 3.57e-113 342.0 COG3507@1|root,COG3507@2|Bacteria,1NNX4@1224|Proteobacteria,2U06C@28211|Alphaproteobacteria,43ZEC@69657|Hyphomonadaceae 28211|Alphaproteobacteria G Belongs to the glycosyl hydrolase 43 family - - 3.2.1.37,3.2.1.55 ko:K01198,ko:K01209 ko00520,ko01100,map00520,map01100 - R01433,R01762 RC00467 ko00000,ko00001,ko01000 - GH43,GH51 - Glyco_hydro_43 k141_23522_1 218284.CCDN010000001_gene1814 4.18e-61 202.0 COG2508@1|root,COG2508@2|Bacteria,1TSQP@1239|Firmicutes,4HB10@91061|Bacilli,1ZBH4@1386|Bacillus 91061|Bacilli QT Purine catabolism regulatory protein-like family - - - ko:K09684 - - - - ko00000,ko03000 - - - HTH_30,PucR k141_14115_1 935836.JAEL01000106_gene4600 4.5e-37 125.0 2E4ES@1|root,32Z9Y@2|Bacteria,1VF84@1239|Firmicutes,4HNYS@91061|Bacilli,1ZHX6@1386|Bacillus 91061|Bacilli K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan mtrB - - ko:K06285 - - - - ko00000,ko03000 - - - TrpBP k141_22187_1 558169.AGAV01000015_gene406 1.11e-101 305.0 COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,4H9WQ@91061|Bacilli 91061|Bacilli E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase - - - - - - - - - - - - M20_dimer,Peptidase_M20 k141_18795_1 1169144.KB910950_gene3251 2.96e-62 201.0 28PJY@1|root,2ZC9F@2|Bacteria,1V390@1239|Firmicutes,4HG7F@91061|Bacilli,1ZDN7@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF1836) ykrK - - - - - - - - - - - DUF1836 k141_3062_1 218284.CCDN010000002_gene2237 5.85e-137 404.0 COG3275@1|root,COG3275@2|Bacteria,1VTXF@1239|Firmicutes,4H9Z1@91061|Bacilli,1ZBKQ@1386|Bacillus 91061|Bacilli T Histidine kinase lytS - 2.7.13.3 ko:K07704 ko02020,map02020 M00492 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - 5TM-5TMR_LYT,GAF_3,HATPase_c,His_kinase k141_7854_2 218284.CCDN010000002_gene2907 6.17e-181 524.0 COG0753@1|root,COG0753@2|Bacteria,1TPPV@1239|Firmicutes,4H9XQ@91061|Bacilli,1ZB44@1386|Bacillus 91061|Bacilli P serves to protect cells from the toxic effects of hydrogen peroxide katE GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0042221,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070887,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1990748 1.11.1.6 ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 M00532 R00009,R00602,R02670 RC00034,RC00767,RC02141,RC02755 ko00000,ko00001,ko00002,ko01000 - - - Catalase,Catalase-rel,DJ-1_PfpI k141_23523_1 1500894.JQNN01000001_gene3771 3.59e-79 249.0 COG4962@1|root,COG4962@2|Bacteria,1R7EN@1224|Proteobacteria,2VJWJ@28216|Betaproteobacteria,475QS@75682|Oxalobacteraceae 28216|Betaproteobacteria U Type II/IV secretion system protein cpaF1 - - ko:K02283 - - - - ko00000,ko02035,ko02044 - - - T2SSE k141_22188_2 742741.HMPREF9475_00384 2.15e-15 77.8 COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,248W2@186801|Clostridia,21YHD@1506553|Lachnoclostridium 186801|Clostridia J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs truA - 5.4.99.12 ko:K06173 - - - - ko00000,ko01000,ko03016 - - - PseudoU_synth_1 k141_36264_1 935837.JAEK01000013_gene4912 9.22e-48 169.0 arCOG10178@1|root,2ZAAA@2|Bacteria,1VC6Y@1239|Firmicutes,4HKZP@91061|Bacilli,1ZGRV@1386|Bacillus 91061|Bacilli S CAAX protease self-immunity - - - - - - - - - - - - Abi k141_16200_1 351746.Pput_1451 8.77e-83 259.0 COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,1RMJR@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex bkdB - 2.3.1.168 ko:K09699 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 M00036 R02662,R03174,R04097,R10998 RC00004,RC02727,RC02870 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding k141_23524_1 1385511.N783_20225 2.43e-57 183.0 COG1388@1|root,COG2340@1|root,COG1388@2|Bacteria,COG2340@2|Bacteria,1V6GZ@1239|Firmicutes,4HDFU@91061|Bacilli,2Y9VR@289201|Pontibacillus 91061|Bacilli M Cysteine-rich secretory protein family - - - - - - - - - - - - CAP,LysM k141_18796_1 1117379.BABA_01035 0.000106 43.9 COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,4HA70@91061|Bacilli,1ZCE3@1386|Bacillus 91061|Bacilli F Belongs to the GARS family purD - 6.3.4.13 ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144 RC00090,RC00166 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS05245,iYO844.BSU06530 GARS_A,GARS_C,GARS_N k141_18796_2 218284.CCDN010000002_gene1994 1.75e-50 165.0 2EAXM@1|root,334YP@2|Bacteria,1VIHS@1239|Firmicutes,4HR0C@91061|Bacilli,1ZJ0E@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2892) - - - - - - - - - - - - DUF2892 k141_6776_1 1294265.JCM21738_2586 5.37e-151 429.0 COG0078@1|root,COG0078@2|Bacteria,1TPF2@1239|Firmicutes,4H9X8@91061|Bacilli,1ZC5E@1386|Bacillus 91061|Bacilli E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline argF GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 M00029,M00844 R01398 RC00096 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N k141_14117_1 1385511.N783_20105 6.49e-95 291.0 COG0477@1|root,COG2814@2|Bacteria,1TRVP@1239|Firmicutes,4IQRS@91061|Bacilli,2Y94F@289201|Pontibacillus 91061|Bacilli EGP Tetracycline resistance protein TetA - - - ko:K08168 - M00704 - - ko00000,ko00002,ko01504,ko02000 2.A.1.3.16,2.A.1.3.22,2.A.1.3.6 - - MFS_1,Sugar_tr k141_1854_1 247634.GPB2148_3061 6.3e-56 196.0 COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,1MX3A@1224|Proteobacteria,1RMQZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria QU COG0823 Periplasmic component of the Tol biopolymer transport system - - - - - - - - - - - - Amidohydro_1,PD40 k141_24594_1 886293.Sinac_0562 1.08e-53 186.0 COG3391@1|root,COG3391@2|Bacteria,2J3CG@203682|Planctomycetes 203682|Planctomycetes S 56kDa selenium binding protein (SBP56) - - - ko:K17285 - - - - ko00000,ko04147 - - - SBP56 k141_9210_1 314265.R2601_10679 1.07e-99 308.0 COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,1MUXX@1224|Proteobacteria,2TQYC@28211|Alphaproteobacteria 28211|Alphaproteobacteria I Methylmalonyl-CoA mutase mutB - 5.4.99.63 ko:K14447 ko00630,ko01120,ko01200,map00630,map01120,map01200 M00373 R09292 RC02835 ko00000,ko00001,ko00002,ko01000 - - - B12-binding,MM_CoA_mutase k141_29279_2 1279017.AQYJ01000028_gene2334 3.87e-229 650.0 COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,1RNRX@1236|Gammaproteobacteria,464V1@72275|Alteromonadaceae 1236|Gammaproteobacteria P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) ppk GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006082,GO:0006091,GO:0006139,GO:0006163,GO:0006165,GO:0006464,GO:0006468,GO:0006725,GO:0006753,GO:0006757,GO:0006793,GO:0006796,GO:0006797,GO:0006799,GO:0006807,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009117,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009179,GO:0009185,GO:0009199,GO:0009205,GO:0009259,GO:0009279,GO:0009358,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016778,GO:0017144,GO:0019538,GO:0019637,GO:0019693,GO:0019867,GO:0030312,GO:0030313,GO:0031241,GO:0031975,GO:0032991,GO:0034641,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0043751,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044425,GO:0044462,GO:0044464,GO:0046031,GO:0046034,GO:0046483,GO:0046777,GO:0046939,GO:0055086,GO:0061695,GO:0071704,GO:0071944,GO:0072521,GO:0098552,GO:1901135,GO:1901360,GO:1901564,GO:1901576,GO:1902494,GO:1990234 2.7.4.1 ko:K00937 ko00190,ko03018,map00190,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - iSbBS512_1146.SbBS512_E2875 PP_kinase,PP_kinase_C,PP_kinase_N k141_3063_1 218284.CCDN010000004_gene3141 5.52e-162 463.0 COG0114@1|root,COG0114@2|Bacteria,1UHPH@1239|Firmicutes,4HA6P@91061|Bacilli,1ZS23@1386|Bacillus 91061|Bacilli C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate fumC GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 M00009,M00011,M00173,M00376 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS09430 FumaraseC_C,Lyase_1 k141_35317_1 1116375.VEJY3_12345 0.0 1557.0 COG1330@1|root,COG1330@2|Bacteria,1MWTI@1224|Proteobacteria,1RNT0@1236|Gammaproteobacteria,1XTXU@135623|Vibrionales 135623|Vibrionales L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity recC - 3.1.11.5 ko:K03583 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_V_gamma k141_35317_2 1116375.VEJY3_12340 1.97e-187 555.0 COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,1RPC6@1236|Gammaproteobacteria,1XTTM@135623|Vibrionales 135623|Vibrionales L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA recB - 3.1.11.5 ko:K03582 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - PDDEXK_1,UvrD-helicase,UvrD_C k141_23526_1 218284.CCDN010000005_gene3479 8.76e-84 255.0 COG1226@1|root,COG1226@2|Bacteria,1TS7X@1239|Firmicutes,4HCIB@91061|Bacilli,1ZCD3@1386|Bacillus 91061|Bacilli P COG1226 Kef-type K transport systems yugO - - ko:K10716 - - - - ko00000,ko02000 1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6 - - Ion_trans_2,TrkA_N k141_6778_1 218284.CCDN010000001_gene417 2.98e-80 241.0 COG0697@1|root,COG0697@2|Bacteria,1V038@1239|Firmicutes,4HDBV@91061|Bacilli,1ZQ3A@1386|Bacillus 91061|Bacilli EG EamA-like transporter family - - - - - - - - - - - - EamA k141_30310_1 1385514.N782_06740 1.19e-31 115.0 2A6RZ@1|root,32MU7@2|Bacteria,1U2DP@1239|Firmicutes,4IBZD@91061|Bacilli,2YBNK@289201|Pontibacillus 91061|Bacilli S Predicted integral membrane protein (DUF2269) - - - - - - - - - - - - DUF2269 k141_878_2 42565.FP66_01780 7.05e-65 200.0 COG3160@1|root,COG3160@2|Bacteria,1RHBB@1224|Proteobacteria,1S420@1236|Gammaproteobacteria,1XJP0@135619|Oceanospirillales 135619|Oceanospirillales K Belongs to the Rsd AlgQ family - - - ko:K07740 - - - - ko00000 - - - Rsd_AlgQ k141_19837_1 1294265.JCM21738_3779 1.11e-96 288.0 COG0826@1|root,COG0826@2|Bacteria,1TPCZ@1239|Firmicutes,4HC7A@91061|Bacilli,1ZC7A@1386|Bacillus 91061|Bacilli O peptidase U32 - - - - - - - - - - - - - k141_1855_1 42565.FP66_13850 8.26e-142 405.0 COG0352@1|root,COG0494@1|root,COG0352@2|Bacteria,COG0494@2|Bacteria,1RCZM@1224|Proteobacteria,1RS3S@1236|Gammaproteobacteria,1XJAD@135619|Oceanospirillales 135619|Oceanospirillales HL COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - - NUDIX,NUDIX_4,TMP-TENI k141_10397_1 218284.CCDN010000001_gene1544 6.32e-191 542.0 COG1686@1|root,COG1686@2|Bacteria,1TQN0@1239|Firmicutes,4HBD4@91061|Bacilli,1ZAS6@1386|Bacillus 91061|Bacilli M Belongs to the peptidase S11 family dacA GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0009002,GO:0016787,GO:0017171,GO:0019538,GO:0030312,GO:0043170,GO:0044238,GO:0044464,GO:0070008,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.16.4 ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - PBP5_C,Peptidase_S11 k141_18798_1 218284.CCDN010000001_gene1807 3.98e-151 444.0 COG0323@1|root,COG0323@2|Bacteria,1TPGK@1239|Firmicutes,4HB34@91061|Bacilli,1ZB9X@1386|Bacillus 91061|Bacilli L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex mutL GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032300,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1990391 - ko:K03572 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - DNA_mis_repair,HATPase_c_3,MutL_C k141_27207_1 1042377.AFPJ01000019_gene2500 2.64e-96 302.0 COG0128@1|root,COG0287@1|root,COG0128@2|Bacteria,COG0287@2|Bacteria,1MWMK@1224|Proteobacteria,1RQ8U@1236|Gammaproteobacteria,46511@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate aroA - 1.3.1.12,1.3.1.43,2.5.1.19 ko:K00210,ko:K00220,ko:K00800 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00022,M00025,M00040 R00732,R01728,R03460 RC00125,RC00350 ko00000,ko00001,ko00002,ko01000 - - - EPSP_synthase,PDH k141_9211_1 1285586.H131_09148 7.4e-08 55.5 COG0514@1|root,COG0514@2|Bacteria,1TPN5@1239|Firmicutes,4H9QP@91061|Bacilli,3IWC2@400634|Lysinibacillus 91061|Bacilli L DNA helicase recQ GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009378,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.6.4.12 ko:K03654 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecQ_Zn_bind k141_9211_2 218284.CCDN010000001_gene1072 8.6e-89 266.0 COG1266@1|root,COG1266@2|Bacteria,1V4WK@1239|Firmicutes,4HHKM@91061|Bacilli,1ZEBP@1386|Bacillus 91061|Bacilli S metal-dependent membrane protease ypbD - - ko:K07052 - - - - ko00000 - - - Abi k141_36266_2 218284.CCDN010000007_gene3914 8.68e-36 130.0 COG1957@1|root,COG1957@2|Bacteria,1TRDA@1239|Firmicutes,4HDED@91061|Bacilli,1ZQTI@1386|Bacillus 91061|Bacilli F Inosine-uridine preferring nucleoside hydrolase - - 3.2.2.1 ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 - R01245,R01273,R01677,R01770,R02143 RC00033,RC00063,RC00122,RC00318,RC00485 ko00000,ko00001,ko01000 - - - IU_nuc_hydro k141_30487_1 1403313.AXBR01000026_gene5172 4.74e-69 218.0 COG1396@1|root,COG1396@2|Bacteria,1V1KD@1239|Firmicutes,4HG1Q@91061|Bacilli,1ZEYC@1386|Bacillus 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_19,HTH_3,TPR_12,TPR_8 k141_7975_2 326423.RBAM_001160 8.61e-96 280.0 COG0245@1|root,COG0245@2|Bacteria,1V3P0@1239|Firmicutes,4HG1X@91061|Bacilli,1ZB1U@1386|Bacillus 91061|Bacilli I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) ispF - 2.7.7.60,4.6.1.12 ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05633,R05637 RC00002,RC01440 ko00000,ko00001,ko00002,ko01000 - - - YgbB k141_35660_1 218284.CCDN010000002_gene2010 2.13e-173 489.0 COG0078@1|root,COG0078@2|Bacteria,1TPF2@1239|Firmicutes,4H9X8@91061|Bacilli,1ZC5E@1386|Bacillus 91061|Bacilli E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline argF GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 M00029,M00844 R01398 RC00096 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N k141_35660_2 218284.CCDN010000002_gene2009 1.31e-81 270.0 COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,4HABE@91061|Bacilli,1ZPZA@1386|Bacillus 91061|Bacilli EF Carbamoyl-phosphate synthetase ammonia chain carB GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS k141_20173_1 666686.B1NLA3E_15915 4.24e-67 213.0 COG0581@1|root,COG0581@2|Bacteria,1TP74@1239|Firmicutes,4HAKF@91061|Bacilli,1ZDAY@1386|Bacillus 91061|Bacilli P Phosphate transport system permease pstA - - ko:K02038 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 k141_20173_2 441769.ABFU01000042_gene3229 7.95e-153 437.0 COG0573@1|root,COG0573@2|Bacteria,1TSPP@1239|Firmicutes,4HC9H@91061|Bacilli,1ZAUU@1386|Bacillus 91061|Bacilli P probably responsible for the translocation of the substrate across the membrane pstC - - ko:K02037 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 k141_34331_2 1379698.RBG1_1C00001G1211 7.8e-75 239.0 COG0034@1|root,COG0034@2|Bacteria,2NNSY@2323|unclassified Bacteria 2|Bacteria F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine purF GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009507,GO:0009536,GO:0040007,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 - - iSB619.SA_RS05225 GATase_6,GATase_7,Pribosyltran k141_13063_1 390989.JOEG01000014_gene3114 7.81e-68 221.0 COG1757@1|root,COG1757@2|Bacteria,2I8CQ@201174|Actinobacteria,4D96Q@85008|Micromonosporales 201174|Actinobacteria C Na+/H+ antiporter family nhaC - - ko:K03315 - - - - ko00000,ko02000 2.A.35 - - Na_H_antiporter k141_21128_1 218284.CCDN010000002_gene2554 1.03e-137 405.0 COG4533@1|root,COG4533@2|Bacteria,1TRY2@1239|Firmicutes,4HBZ3@91061|Bacilli,1ZAUC@1386|Bacillus 91061|Bacilli S Sugar transport-related sRNA regulator N-term - - - - - - - - - - - - SBP_bac_5,SgrR_N k141_35662_1 558169.AGAV01000003_gene2666 3.61e-56 193.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1TQ85@1239|Firmicutes,4HAC0@91061|Bacilli 91061|Bacilli EU peptidase - - - - - - - - - - - - PD40,Peptidase_S9,Peptidase_S9_N k141_7977_1 935836.JAEL01000008_gene3902 3.76e-19 87.0 COG3284@1|root,COG5002@1|root,COG3284@2|Bacteria,COG5002@2|Bacteria,1VUBP@1239|Firmicutes,4HUPW@91061|Bacilli,1ZS15@1386|Bacillus 91061|Bacilli T Histidine kinase kinA - 2.7.13.3 ko:K02491 ko02020,map02020 M00485 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - 5TM-5TMR_LYT,HATPase_c,HisKA,MASE3,MHYT,PAS,PAS_3,PAS_4,PAS_9 k141_37743_1 247634.GPB2148_408 1.38e-64 207.0 COG3751@1|root,COG3751@2|Bacteria,1RE5K@1224|Proteobacteria,1RQ24@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Prolyl 4-hydroxylase alpha subunit homologues. - - - - - - - - - - - - 2OG-FeII_Oxy_4 k141_37743_3 1453501.JELR01000002_gene326 1.34e-307 860.0 COG1629@1|root,COG4206@1|root,COG4206@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria,464NB@72275|Alteromonadaceae 1236|Gammaproteobacteria P Outer membrane receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_29607_1 1116375.VEJY3_22126 3.06e-79 261.0 COG0493@1|root,COG3383@1|root,COG0493@2|Bacteria,COG3383@2|Bacteria,1MU2H@1224|Proteobacteria,1SMV9@1236|Gammaproteobacteria,1Y32S@135623|Vibrionales 135623|Vibrionales C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - 1.17.1.9 ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001,ko01000 - - - Fer2_4,Fer4,Fer4_20,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,Pyr_redox_2 k141_13064_1 1121930.AQXG01000001_gene1102 6.17e-47 173.0 COG2091@1|root,COG2091@2|Bacteria,4NGXG@976|Bacteroidetes 976|Bacteroidetes H lysine biosynthetic process via aminoadipic acid - - - - - - - - - - - - CBM9_1 k141_28187_1 223926.28807377 1.16e-54 171.0 COG3141@1|root,COG3141@2|Bacteria,1N6RQ@1224|Proteobacteria,1SCDB@1236|Gammaproteobacteria,1XXX8@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria - - - ko:K09918 - - - - ko00000 - - - YebG k141_28187_2 1116375.VEJY3_12360 5.67e-104 307.0 COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,1RPT8@1236|Gammaproteobacteria,1XTXE@135623|Vibrionales 135623|Vibrionales K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_2112_1 218284.CCDN010000010_gene4394 2.32e-137 411.0 COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HACY@91061|Bacilli,1ZB4C@1386|Bacillus 91061|Bacilli O Belongs to the ClpA ClpB family clpC GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 - ko:K03696 ko01100,map01100 - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N,UVR k141_3343_1 218284.CCDN010000004_gene3103 4.1e-228 634.0 COG2610@1|root,COG2610@2|Bacteria,1TQJ6@1239|Firmicutes,4HA01@91061|Bacilli,1ZCGI@1386|Bacillus 91061|Bacilli EG COG2610 H gluconate symporter and related permeases - - - - - - - - - - - - GntP_permease k141_35663_1 1294265.JCM21738_3832 5.25e-43 140.0 2BABF@1|root,323RS@2|Bacteria,1UAR7@1239|Firmicutes,4IM3X@91061|Bacilli,1ZJ2V@1386|Bacillus 91061|Bacilli S IDEAL - - - - - - - - - - - - IDEAL k141_35663_2 1294265.JCM21738_3831 2.07e-68 210.0 COG4903@1|root,COG4903@2|Bacteria,1V4S5@1239|Firmicutes,4HHF4@91061|Bacilli,1ZGB4@1386|Bacillus 91061|Bacilli K Competence transcription factor comK - - ko:K02250 ko02024,map02024 - - - ko00000,ko00001,ko02044,ko03000 - - - ComK k141_10569_1 1279017.AQYJ01000028_gene2404 8.11e-180 529.0 COG4772@1|root,COG4772@2|Bacteria,1MUIH@1224|Proteobacteria,1RQYX@1236|Gammaproteobacteria,46D6R@72275|Alteromonadaceae 1236|Gammaproteobacteria P TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_17611_1 1042377.AFPJ01000030_gene447 1.57e-86 279.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MV8W@1224|Proteobacteria,1RMQA@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Outer membrane receptor proteins mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec k141_29608_1 1042377.AFPJ01000042_gene1092 1.73e-134 421.0 COG0770@1|root,COG2843@1|root,COG0770@2|Bacteria,COG2843@2|Bacteria,1QTSF@1224|Proteobacteria,1RMGD@1236|Gammaproteobacteria,464UU@72275|Alteromonadaceae 1236|Gammaproteobacteria M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein - - - - - - - - - - - - Mur_ligase_C,Mur_ligase_M,PGA_cap k141_37745_1 1294265.JCM21738_1449 2.41e-107 317.0 COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,4H9SR@91061|Bacilli,1ZCDX@1386|Bacillus 91061|Bacilli S transporter activity yueF - - - - - - - - - - - AI-2E_transport k141_24908_1 1453501.JELR01000001_gene1850 4.83e-42 145.0 COG3769@1|root,COG3769@2|Bacteria,1NFV5@1224|Proteobacteria,1RR9R@1236|Gammaproteobacteria,464IU@72275|Alteromonadaceae 1236|Gammaproteobacteria S Mannosyl-3-phosphoglycerate phosphatase yedP - 2.7.1.31,3.1.3.70 ko:K07026,ko:K15918 ko00051,ko00260,ko00561,ko00630,ko01100,ko01110,ko01130,ko01200,map00051,map00260,map00561,map00630,map01100,map01110,map01130,map01200 M00532 R01514,R05790 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Hydrolase_3,S6PP k141_17612_1 1294265.JCM21738_1662 8.37e-118 343.0 COG1481@1|root,COG1481@2|Bacteria,1TP2X@1239|Firmicutes,4HB4H@91061|Bacilli,1ZBKY@1386|Bacillus 91061|Bacilli K May be required for sporulation whiA GO:0008150,GO:0043937,GO:0050789,GO:0050793,GO:0065007 - ko:K09762 - - - - ko00000 - - - HTH_WhiA,LAGLIDADG_WhiA,WhiA_N k141_33065_2 1238450.VIBNISOn1_370010 2.33e-218 633.0 COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RP53@1236|Gammaproteobacteria,1XWFB@135623|Vibrionales 135623|Vibrionales T His Kinase A (phosphoacceptor) domain - - 2.7.13.3 ko:K08475 ko02020,map02020 M00503 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c k141_33065_3 1238450.VIBNISOn1_370009 4.54e-15 73.9 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1XSE5@135623|Vibrionales 135623|Vibrionales T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - ko:K10126 ko02020,map02020 M00504 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat k141_7978_1 1267535.KB906767_gene14 2.38e-23 99.8 COG2025@1|root,COG2025@2|Bacteria,3Y3JE@57723|Acidobacteria,2JM9U@204432|Acidobacteriia 204432|Acidobacteriia C Electron transfer flavoprotein FAD-binding domain - - - ko:K03522 - - - - ko00000,ko04147 - - - ETF,ETF_alpha k141_7978_2 694431.DESACE_06760 9.4e-42 149.0 COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,42RCI@68525|delta/epsilon subdivisions,2WMYC@28221|Deltaproteobacteria,2M7KH@213113|Desulfurellales 28221|Deltaproteobacteria C Electron transfer flavoprotein domain etfB-7 - - ko:K03521 - - - - ko00000 - - - ETF k141_30490_1 218284.CCDN010000002_gene2679 1.65e-24 93.2 297WH@1|root,2ZV31@2|Bacteria,1W3F8@1239|Firmicutes,4I1H0@91061|Bacilli,1ZKJ7@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_2113_1 1056820.KB900696_gene3993 2e-15 70.5 2ATYA@1|root,31JHY@2|Bacteria,1QAXH@1224|Proteobacteria,1T6D5@1236|Gammaproteobacteria,2PQK4@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_2113_2 1279017.AQYJ01000029_gene3361 1.53e-103 302.0 COG0778@1|root,COG0778@2|Bacteria,1PKUV@1224|Proteobacteria,1RNQG@1236|Gammaproteobacteria,4678D@72275|Alteromonadaceae 1236|Gammaproteobacteria C nitroreductase ydjA GO:0000166,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0010181,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - - - - - - - - - - Nitroreductase k141_24909_1 218284.CCDN010000002_gene2157 6.18e-111 327.0 COG1609@1|root,COG1609@2|Bacteria,1TRFH@1239|Firmicutes,4HE9A@91061|Bacilli,1ZQ1D@1386|Bacillus 91061|Bacilli K helix_turn _helix lactose operon repressor - - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 k141_20177_1 1121090.KB894689_gene295 1.05e-28 111.0 COG0175@1|root,COG0175@2|Bacteria,1TSMI@1239|Firmicutes,4HA9E@91061|Bacilli,1ZCBJ@1386|Bacillus 91061|Bacilli EH Belongs to the PAPS reductase family. CysH subfamily cysH GO:0003674,GO:0003824,GO:0004604,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016667,GO:0016671,GO:0044424,GO:0044464,GO:0055114 1.8.4.10,1.8.4.8 ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00176 R02021 RC00007,RC02862 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU15570 PAPS_reduct k141_29609_2 218284.CCDN010000001_gene1819 6.29e-189 530.0 COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,4HAD5@91061|Bacilli,1ZC3C@1386|Bacillus 91061|Bacilli E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases gltD - 1.3.1.1 ko:K17722 ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100 M00046 R00977,R01414,R11026 RC00072,RC00123 ko00000,ko00001,ko00002,ko01000 - - - Fer4_20,Pyr_redox_2,Pyr_redox_3 k141_3345_1 498211.CJA_2848 6.09e-35 127.0 COG3485@1|root,COG3485@2|Bacteria,1MV6K@1224|Proteobacteria,1S376@1236|Gammaproteobacteria,1FI4G@10|Cellvibrio 1236|Gammaproteobacteria Q Intradiol ring-cleavage dioxygenase - - 1.13.11.3 ko:K00449 ko00362,ko00624,ko01100,ko01120,ko01220,map00362,map00624,map01100,map01120,map01220 - R01631,R03549 RC00388,RC00953 br01602,ko00000,ko00001,ko01000 - - - Dioxygenase_C,TAT_signal k141_3345_2 743721.Psesu_0580 9.84e-33 120.0 28IPG@1|root,2Z8PF@2|Bacteria,1P8KM@1224|Proteobacteria,1RY74@1236|Gammaproteobacteria,1X65A@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - k141_24910_1 218284.CCDN010000006_gene3762 1.2e-42 144.0 COG1999@1|root,COG1999@2|Bacteria,1V03J@1239|Firmicutes,4IBXB@91061|Bacilli,1ZH9Z@1386|Bacillus 91061|Bacilli S SCO1/SenC - - - - - - - - - - - - SCO1-SenC k141_30491_1 1492737.FEM08_32050 4.67e-08 54.7 COG3383@1|root,COG3383@2|Bacteria 2|Bacteria C formate dehydrogenase (NAD+) activity fdsA - 1.17.1.10,1.17.1.9 ko:K00123,ko:K05299 ko00630,ko00680,ko00720,ko01100,ko01120,ko01200,map00630,map00680,map00720,map01100,map01120,map01200 M00377 R00134,R00519 RC02796 ko00000,ko00001,ko00002,ko01000 - - - Fer2_4,Fer4,Fer4_7,Fer4_9,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3 k141_30491_2 247490.KSU1_C0501 3.27e-17 83.6 COG3383@1|root,COG3383@2|Bacteria,2J4XN@203682|Planctomycetes 203682|Planctomycetes C 2Fe-2S iron-sulfur cluster binding domain - - 1.17.1.9 ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001,ko01000 - - - Fer2_4,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3 k141_20178_1 1294265.JCM21738_4143 2.78e-98 298.0 COG0376@1|root,COG0376@2|Bacteria,1TQDA@1239|Firmicutes,4HBZ5@91061|Bacilli,1ZD07@1386|Bacillus 91061|Bacilli P Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity katG - 1.11.1.21 ko:K03782 ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110 - R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906 RC00034,RC00213,RC00767,RC02141 ko00000,ko00001,ko01000 - - - peroxidase k141_21134_1 1423321.AS29_07595 2.87e-119 371.0 COG0085@1|root,COG0085@2|Bacteria,1TP96@1239|Firmicutes,4H9PK@91061|Bacilli,1ZBPC@1386|Bacillus 91061|Bacilli K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoB GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 k141_37747_1 1236976.JCM16418_2609 1.05e-20 95.5 COG2199@1|root,COG2199@2|Bacteria,1TR65@1239|Firmicutes,4HBA6@91061|Bacilli,26RG7@186822|Paenibacillaceae 91061|Bacilli T Diguanylate cyclase - - - - - - - - - - - - GGDEF,dCache_1 k141_37748_1 1432055.GLUCORHAEAF1_17755 2.06e-60 201.0 COG1887@1|root,COG1887@2|Bacteria,1R4MQ@1224|Proteobacteria,2U1UT@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC - - - - - - - - - - - - - k141_20180_2 1116375.VEJY3_17371 1.77e-76 236.0 COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,1RMR8@1236|Gammaproteobacteria,1XSH2@135623|Vibrionales 135623|Vibrionales P Cation efflux family - - - - - - - - - - - - Cation_efflux k141_24912_1 1042377.AFPJ01000037_gene2935 3.64e-72 226.0 COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,1RNPX@1236|Gammaproteobacteria,464Y1@72275|Alteromonadaceae 1236|Gammaproteobacteria P Belongs to the ABC transporter superfamily - - 3.6.3.30 ko:K02010 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.10 - - ABC_tran,TOBE_2 k141_17617_1 1294265.JCM21738_5499 3.92e-133 384.0 28PT3@1|root,2ZCEG@2|Bacteria,1V3FJ@1239|Firmicutes,4HG7M@91061|Bacilli,1ZFCJ@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF4179) - - - - - - - - - - - - DUF4179 k141_21135_1 234267.Acid_1289 2.66e-40 141.0 2DEWU@1|root,2ZPJP@2|Bacteria,3Y585@57723|Acidobacteria 57723|Acidobacteria - - - - - - - - - - - - - - - k141_21135_2 861299.J421_6223 1.93e-18 87.8 COG2091@1|root,COG2091@2|Bacteria,1ZUE3@142182|Gemmatimonadetes 142182|Gemmatimonadetes H lysine biosynthetic process via aminoadipic acid - - - - - - - - - - - - - k141_4548_1 1279017.AQYJ01000029_gene3767 0.0 995.0 COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,1RMDS@1236|Gammaproteobacteria,464FV@72275|Alteromonadaceae 1236|Gammaproteobacteria J Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs rne - 3.1.26.12 ko:K08300 ko03018,map03018 M00394 - - ko00000,ko00001,ko00002,ko01000,ko03009,ko03019 - - - RNase_E_G,S1 k141_10597_4 981383.AEWH01000015_gene3817 1.25e-17 79.0 2ENX8@1|root,33GI6@2|Bacteria,1VJKN@1239|Firmicutes,4HQGG@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - k141_10597_5 1234664.AMRO01000024_gene1796 1.4e-58 187.0 2DM82@1|root,324KK@2|Bacteria,1V9IJ@1239|Firmicutes,4HJEV@91061|Bacilli,1WGSK@129337|Geobacillus 91061|Bacilli - - - - 3.1.22.4 ko:K01159 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - - k141_10597_7 1462526.BN990_01832 6.33e-42 145.0 COG4508@1|root,COG4508@2|Bacteria,1V6PI@1239|Firmicutes,4HJBB@91061|Bacilli,4C60A@84406|Virgibacillus 91061|Bacilli S dUTPase - - - - - - - - - - - - dUTPase_2 k141_10597_9 386043.lwe0036 6.27e-54 175.0 COG0629@1|root,COG0629@2|Bacteria,1V3WT@1239|Firmicutes,4HH8I@91061|Bacilli,26JMX@186820|Listeriaceae 91061|Bacilli L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k141_10597_11 95619.PM1_0217555 3.62e-17 81.6 COG2197@1|root,COG2197@2|Bacteria,1NA3X@1224|Proteobacteria 1224|Proteobacteria KT HNH endonuclease - - - - - - - - - - - - HNH_3 k141_10597_12 1444310.JANV01000162_gene1200 7.98e-54 175.0 29P1D@1|root,309ZJ@2|Bacteria,1U5ZP@1239|Firmicutes,4IFNP@91061|Bacilli,1ZPBS@1386|Bacillus 91061|Bacilli S HNH nucleases - - - - - - - - - - - - - k141_34365_1 641147.HMPREF9021_00717 1.7e-09 61.6 COG1496@1|root,COG1496@2|Bacteria,1MW2H@1224|Proteobacteria,2VKD4@28216|Betaproteobacteria,2KPKE@206351|Neisseriales 206351|Neisseriales S Belongs to the multicopper oxidase YfiH RL5 family yfiH - - ko:K05810 - - - - ko00000,ko01000 - - - Cu-oxidase_4 k141_37795_1 218284.CCDN010000002_gene2890 1.82e-45 154.0 COG0614@1|root,COG0614@2|Bacteria,1TQMK@1239|Firmicutes,4HBP4@91061|Bacilli,1ZBTM@1386|Bacillus 91061|Bacilli P ABC transporter fhuD GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 - ko:K02016 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - Peripla_BP_2 k141_16517_1 886293.Sinac_2688 1.73e-24 102.0 COG3379@1|root,COG3379@2|Bacteria,2IYF3@203682|Planctomycetes 2|Bacteria P Type I phosphodiesterase / nucleotide pyrophosphatase - - - - - - - - - - - - Phosphodiest k141_3388_1 1453501.JELR01000005_gene1697 1.03e-83 267.0 COG4247@1|root,COG4247@2|Bacteria,1MVTA@1224|Proteobacteria,1RQXH@1236|Gammaproteobacteria,46571@72275|Alteromonadaceae 1236|Gammaproteobacteria I Phytase phy - 3.1.3.8 ko:K01083 ko00562,map00562 - R03371 RC00078 ko00000,ko00001,ko01000 - - - Phytase k141_21184_1 218284.CCDN010000010_gene4368 6.11e-225 623.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,4HAEH@91061|Bacilli,1ZCZK@1386|Bacillus 91061|Bacilli J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis tuf GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K02358 - - - - ko00000,ko03012,ko03029,ko04147 - - iSB619.SA_RS02960 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 k141_36491_1 218284.CCDN010000001_gene207 4.28e-157 446.0 COG0714@1|root,COG0714@2|Bacteria,1TPKR@1239|Firmicutes,4HA0T@91061|Bacilli,1ZCN3@1386|Bacillus 91061|Bacilli S ATPase family associated with various cellular activities (AAA) - - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 k141_17679_1 1294265.JCM21738_5158 1.59e-112 352.0 COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,4H9T3@91061|Bacilli,1ZCIC@1386|Bacillus 91061|Bacilli L DNA polymerase dnaE - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon k141_8020_1 218284.CCDN010000007_gene4016 1.75e-39 132.0 COG4327@1|root,COG4327@2|Bacteria,1VDN3@1239|Firmicutes,4HM2W@91061|Bacilli,1ZHM0@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF4212) - - - - - - - - - - - - DUF4212 k141_4599_1 1123054.KB907739_gene3207 3.78e-13 67.8 COG1253@1|root,COG1253@2|Bacteria,1R0P6@1224|Proteobacteria,1T4MB@1236|Gammaproteobacteria,1X2SB@135613|Chromatiales 135613|Chromatiales S CBS domain - - - - - - - - - - - - CBS k141_4599_2 1042377.AFPJ01000024_gene814 2.29e-117 341.0 COG3751@1|root,COG3751@2|Bacteria,1RD3H@1224|Proteobacteria,1S40I@1236|Gammaproteobacteria,46712@72275|Alteromonadaceae 1236|Gammaproteobacteria O 2OG-Fe(II) oxygenase - - - ko:K07394 - - - - ko00000 - - - 2OG-FeII_Oxy_3 k141_4599_3 1279017.AQYJ01000028_gene2167 3.42e-222 618.0 COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,1RN2A@1236|Gammaproteobacteria,464MN@72275|Alteromonadaceae 1236|Gammaproteobacteria E The glycine cleavage system catalyzes the degradation of glycine gcvT GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.1.2.10 ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 M00532 R01221,R02300,R04125 RC00022,RC00069,RC00183,RC02834 ko00000,ko00001,ko00002,ko01000 - - iSFV_1184.SFV_2953 GCV_T,GCV_T_C k141_33112_2 218284.CCDN010000002_gene2782 1.54e-240 668.0 COG2262@1|root,COG2262@2|Bacteria,1TNZB@1239|Firmicutes,4HACA@91061|Bacilli,1ZBT6@1386|Bacillus 91061|Bacilli S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis hflX - - ko:K03665 - - - - ko00000,ko03009 - - - GTP-bdg_M,GTP-bdg_N,MMR_HSR1 k141_15215_1 218284.CCDN010000002_gene2224 1.2e-153 435.0 COG1291@1|root,COG1291@2|Bacteria,1TRH1@1239|Firmicutes,4HAXG@91061|Bacilli,1ZB8I@1386|Bacillus 91061|Bacilli N flagellar motor motA GO:0001539,GO:0005575,GO:0005623,GO:0005886,GO:0006928,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0040011,GO:0044425,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071944,GO:0071973,GO:0071978,GO:0097588 - ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - MotA_ExbB k141_15215_2 218284.CCDN010000002_gene2225 2.93e-142 406.0 COG1360@1|root,COG1360@2|Bacteria,1UXY4@1239|Firmicutes,4HCCI@91061|Bacilli,1ZB4F@1386|Bacillus 91061|Bacilli N Flagellar motor protein motB - - ko:K02557 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - MotB_plug,OmpA k141_8448_3 1517681.HW45_22480 7.81e-142 405.0 COG4786@1|root,COG4786@2|Bacteria,1MVMA@1224|Proteobacteria,1RMJ2@1236|Gammaproteobacteria,1XTV1@135623|Vibrionales 135623|Vibrionales N Belongs to the flagella basal body rod proteins family - - - ko:K02392 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C k141_8448_4 443152.MDG893_08245 1.18e-41 149.0 COG4787@1|root,COG4787@2|Bacteria,1NZWQ@1224|Proteobacteria,1RNVX@1236|Gammaproteobacteria,464SB@72275|Alteromonadaceae 1236|Gammaproteobacteria N Flagellar basal body rod protein flgF - - ko:K02391 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C k141_8448_5 945543.VIBR0546_10889 4.69e-153 446.0 COG1749@1|root,COG1749@2|Bacteria,1MU5J@1224|Proteobacteria,1RMWX@1236|Gammaproteobacteria,1XV3D@135623|Vibrionales 135623|Vibrionales N Flagellar hook protein FlgE flgE - - ko:K02390 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FlaE,Flg_bb_rod,Flg_bbr_C k141_8448_6 357804.Ping_3576 2.48e-61 198.0 COG1843@1|root,COG1843@2|Bacteria,1MXCG@1224|Proteobacteria,1RPZI@1236|Gammaproteobacteria,2QIFA@267894|Psychromonadaceae 1236|Gammaproteobacteria N Required for flagellar hook formation. May act as a scaffolding protein flgD - - ko:K02389 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FLgD_tudor,FlgD,FlgD_ig k141_8448_7 1517681.HW45_22460 9.97e-64 198.0 COG1558@1|root,COG1558@2|Bacteria,1RJB8@1224|Proteobacteria,1S8B7@1236|Gammaproteobacteria,1XWWM@135623|Vibrionales 1236|Gammaproteobacteria N Belongs to the flagella basal body rod proteins family - - - ko:K02388 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C k141_8448_8 223926.28808402 6.71e-34 120.0 COG1815@1|root,COG1815@2|Bacteria,1MZ8P@1224|Proteobacteria,1S9DS@1236|Gammaproteobacteria,1XXCT@135623|Vibrionales 135623|Vibrionales N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body - - - ko:K02387 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod k141_8448_10 1517681.HW45_22445 1.95e-23 94.7 COG1886@1|root,COG1886@2|Bacteria 2|Bacteria N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation fliN - - ko:K02417 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 - - FliMN_C k141_8448_11 1517681.HW45_22440 9.55e-40 140.0 COG1338@1|root,COG1338@2|Bacteria,1MVBU@1224|Proteobacteria,1RMYH@1236|Gammaproteobacteria,1XV0T@135623|Vibrionales 135623|Vibrionales N Plays a role in the flagellum-specific transport system - - - ko:K02419 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - FliP k141_16710_1 1453501.JELR01000002_gene916 1.65e-93 287.0 COG3397@1|root,COG3397@2|Bacteria,1PHJ4@1224|Proteobacteria,1RX67@1236|Gammaproteobacteria,46B8E@72275|Alteromonadaceae 1236|Gammaproteobacteria S Lytic polysaccharide mono-oxygenase, cellulose-degrading - - - - - - - - - - - - LPMO_10 k141_34570_2 1279017.AQYJ01000019_gene1489 3.88e-199 555.0 COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,1RPR7@1236|Gammaproteobacteria,4645T@72275|Alteromonadaceae 1236|Gammaproteobacteria H Belongs to the FPP GGPP synthase family ispB GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009108,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663 2.5.1.90 ko:K02523 ko00900,ko01110,map00900,map01110 - R09248 RC00279 ko00000,ko00001,ko01000,ko01006 - - iYL1228.KPN_03597,ic_1306.c3945 polyprenyl_synt k141_34570_4 1042377.AFPJ01000029_gene560 1.97e-188 525.0 COG1210@1|root,COG1210@2|Bacteria,1MV5F@1224|Proteobacteria,1RNDX@1236|Gammaproteobacteria,4650D@72275|Alteromonadaceae 1236|Gammaproteobacteria M UTP-glucose-1-phosphate uridylyltransferase galU - 2.7.7.9 ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 M00129,M00361,M00362,M00549 R00289 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase k141_31021_1 1397699.JNIS01000001_gene44 4.99e-26 108.0 COG0840@1|root,COG0840@2|Bacteria,1TRTV@1239|Firmicutes,4H9M1@91061|Bacilli 91061|Bacilli NT chemotaxis protein hemAT GO:0003674,GO:0005488,GO:0006935,GO:0007154,GO:0007165,GO:0008150,GO:0009453,GO:0009454,GO:0009605,GO:0009987,GO:0020037,GO:0023052,GO:0040011,GO:0042221,GO:0042330,GO:0046906,GO:0048037,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0097159,GO:1901363 - ko:K06595 - - - - ko00000,ko02035 - - - MCPsignal,Protoglobin k141_28648_2 997296.PB1_10062 3.29e-09 56.6 COG1252@1|root,COG1252@2|Bacteria,1TR6X@1239|Firmicutes,4HA14@91061|Bacilli,1ZAV9@1386|Bacillus 91061|Bacilli C NADH dehydrogenase yumB GO:0003674,GO:0003824,GO:0003955,GO:0006091,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0019646,GO:0022900,GO:0022904,GO:0044237,GO:0045333,GO:0055114 1.6.99.3 ko:K03885 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - iYO844.BSU32100 Pyr_redox_2 k141_10765_1 218284.CCDN010000002_gene1995 1.01e-136 403.0 COG1001@1|root,COG1001@2|Bacteria,1TP84@1239|Firmicutes,4HAIR@91061|Bacilli,1ZAY2@1386|Bacillus 91061|Bacilli F adenine deaminase yerA GO:0003674,GO:0003824,GO:0006040,GO:0006044,GO:0006046,GO:0008150,GO:0008152,GO:0008448,GO:0009056,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0046348,GO:0071704,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901575 3.5.4.2 ko:K01486 ko00230,ko01100,map00230,map01100 - R01244 RC00477 ko00000,ko00001,ko01000 - - - Adenine_deam_C,Amidohydro_1 k141_26263_1 1279017.AQYJ01000027_gene1788 1.05e-15 77.0 COG4772@1|root,COG4772@2|Bacteria,1MWDG@1224|Proteobacteria,1RQA5@1236|Gammaproteobacteria,464IF@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG4772 Outer membrane receptor for Fe3 -dicitrate fecA - - ko:K16091 - - - - ko00000,ko02000 1.B.14.1.14 - - Plug,TonB_dep_Rec k141_15567_2 218284.CCDN010000008_gene4146 6.34e-112 335.0 COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HACS@91061|Bacilli,1ZB6H@1386|Bacillus 91061|Bacilli H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily menE - 6.2.1.26 ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R04030 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - AMP-binding,AMP-binding_C k141_4858_1 218284.CCDN010000002_gene2227 2.34e-107 318.0 COG0524@1|root,COG1522@1|root,COG0524@2|Bacteria,COG1522@2|Bacteria,1TQR4@1239|Firmicutes,4H9VM@91061|Bacilli,1ZBUP@1386|Bacillus 91061|Bacilli GK pfkB family carbohydrate kinase - - 2.7.1.83 ko:K16328 ko00240,map00240 - R03315 RC00002,RC00017 ko00000,ko00001,ko01000 - - - HTH_24,PfkB k141_3673_1 886293.Sinac_0217 4.98e-18 84.7 COG2162@1|root,COG2162@2|Bacteria,2J0B7@203682|Planctomycetes 203682|Planctomycetes Q N-acetyltransferase - - 2.3.1.118 ko:K00675 - - - - ko00000,ko01000 - - - Acetyltransf_2 k141_31022_1 477641.MODMU_3255 3.23e-09 62.0 COG5001@1|root,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria,4ERVM@85013|Frankiales 201174|Actinobacteria T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF k141_16729_2 1453501.JELR01000002_gene695 1.81e-19 87.4 COG0705@1|root,COG0705@2|Bacteria,1MYPM@1224|Proteobacteria,1RN1K@1236|Gammaproteobacteria,463ZC@72275|Alteromonadaceae 1236|Gammaproteobacteria S membrane protein (homolog of Drosophila rhomboid) glpG GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019219,GO:0019222,GO:0019538,GO:0031224,GO:0031226,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042802,GO:0043170,GO:0043565,GO:0044212,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:0140096,GO:1901363,GO:1901564,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - ko:K02441 - - - - ko00000 - - - NRho,Rhomboid,Rhomboid_N k141_19121_1 1386089.N865_10655 1.97e-14 77.8 COG1316@1|root,COG1316@2|Bacteria,2GM55@201174|Actinobacteria,4FEYR@85021|Intrasporangiaceae 201174|Actinobacteria K transcriptional regulator - - - - - - - - - - - - LytR_cpsA_psr k141_33384_1 42565.FP66_10400 3.61e-117 343.0 COG1018@1|root,COG1018@2|Bacteria,1MY2Q@1224|Proteobacteria,1RR5A@1236|Gammaproteobacteria,1XHA6@135619|Oceanospirillales 135619|Oceanospirillales C Ferredoxin - - - ko:K21832 - - - - ko00000 - - - FAD_binding_6,Fer2,NAD_binding_1 k141_4873_1 665959.HMPREF1013_02133 6.13e-16 83.2 2E6XT@1|root,331H4@2|Bacteria,1VJ9Y@1239|Firmicutes,4HPEM@91061|Bacilli,1ZBUX@1386|Bacillus 91061|Bacilli - - rsiX GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - Germane k141_4873_2 218284.CCDN010000001_gene1065 6e-16 73.6 COG1595@1|root,COG1595@2|Bacteria,1V4T2@1239|Firmicutes,4HFZ0@91061|Bacilli,1ZEC7@1386|Bacillus 91061|Bacilli K Belongs to the sigma-70 factor family. ECF subfamily sigX GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4,Sigma70_r4_2 k141_3688_1 218284.CCDN010000005_gene3459 3.65e-125 365.0 COG1168@1|root,COG1168@2|Bacteria,1TP5G@1239|Firmicutes,4H9PE@91061|Bacilli,1ZCQC@1386|Bacillus 91061|Bacilli E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities patB - 4.4.1.8 ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 - R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 k141_25046_1 1294265.JCM21738_4420 7.22e-58 182.0 COG0686@1|root,COG0686@2|Bacteria,1TNZ5@1239|Firmicutes,4HABX@91061|Bacilli,1ZBQE@1386|Bacillus 91061|Bacilli E Belongs to the AlaDH PNT family ald GO:0000286,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009987,GO:0016054,GO:0016491,GO:0016638,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.4.1.1 ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 - R00396 RC00008 ko00000,ko00001,ko01000 - - - AlaDh_PNT_C,AlaDh_PNT_N k141_25046_2 717606.PaecuDRAFT_0120 7.53e-27 105.0 COG1227@1|root,COG1227@2|Bacteria,1TPH6@1239|Firmicutes,4H9T8@91061|Bacilli,26SZX@186822|Paenibacillaceae 91061|Bacilli C Catalyzes the hydrolysis of pyrophosphate to phosphate ppaC GO:0003674,GO:0003824,GO:0004427,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0044237,GO:0044424,GO:0044464 3.6.1.1 ko:K15986 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - DHH,DHHA2 k141_26294_1 218284.CCDN010000001_gene1356 3.97e-137 401.0 COG1574@1|root,COG1574@2|Bacteria,1TRB6@1239|Firmicutes,4HFBR@91061|Bacilli,1ZM5P@1386|Bacillus 91061|Bacilli S Amidohydrolase family - - - - - - - - - - - - Amidohydro_3 k141_23853_1 1453501.JELR01000005_gene1578 8.81e-154 434.0 2DKUY@1|root,30EGD@2|Bacteria,1QWUJ@1224|Proteobacteria,1T3JQ@1236|Gammaproteobacteria,46D7Q@72275|Alteromonadaceae 1236|Gammaproteobacteria S SapC - - - - - - - - - - - - SapC k141_9603_1 1122194.AUHU01000002_gene2835 3.52e-44 154.0 COG0725@1|root,COG0725@2|Bacteria,1MVNA@1224|Proteobacteria,1RN71@1236|Gammaproteobacteria,4675T@72275|Alteromonadaceae 1236|Gammaproteobacteria P molybdenum ABC transporter, periplasmic modA - - ko:K02020 ko02010,map02010 M00189 - - ko00000,ko00001,ko00002,ko02000 3.A.1.8 - - SBP_bac_11 k141_9603_2 998674.ATTE01000001_gene1429 7.15e-44 147.0 COG0640@1|root,COG0640@2|Bacteria,1MZT1@1224|Proteobacteria,1SAI5@1236|Gammaproteobacteria,461GP@72273|Thiotrichales 72273|Thiotrichales K PFAM Bacterial regulatory protein, arsR family - - - ko:K03892 - - - - ko00000,ko03000 - - - HTH_5 k141_8472_1 1177181.T9A_01597 1.43e-19 85.9 COG4929@1|root,COG4929@2|Bacteria,1NURJ@1224|Proteobacteria,1SBG7@1236|Gammaproteobacteria 1236|Gammaproteobacteria S GDYXXLXY protein - - - - - - - - - - - - GDYXXLXY k141_8472_2 443152.MDG893_11121 3.04e-28 112.0 COG1266@1|root,COG1266@2|Bacteria,1NIGX@1224|Proteobacteria,1S3TI@1236|Gammaproteobacteria,46BQU@72275|Alteromonadaceae 1236|Gammaproteobacteria S CAAX protease self-immunity - - - ko:K07052 - - - - ko00000 - - - Abi k141_8472_3 1336243.JAEA01000016_gene908 9.46e-25 101.0 COG3926@1|root,COG3926@2|Bacteria,1MVXW@1224|Proteobacteria,2TT3H@28211|Alphaproteobacteria,1JXT2@119045|Methylobacteriaceae 28211|Alphaproteobacteria S Predicted Peptidoglycan domain - - - - - - - - - - - - Glyco_hydro_108,PG_binding_3 k141_6070_1 218284.CCDN010000001_gene1921 3.05e-69 212.0 COG1580@1|root,COG1580@2|Bacteria,1V6K9@1239|Firmicutes,4HIJZ@91061|Bacilli,1ZI2U@1386|Bacillus 91061|Bacilli N Controls the rotational direction of flagella during chemotaxis fliL - - ko:K02415 - - - - ko00000,ko02035 - - - FliL k141_2498_1 1279017.AQYJ01000028_gene2315 1.3e-87 259.0 COG0517@1|root,COG0517@2|Bacteria,1NAGC@1224|Proteobacteria,1SF8G@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain in cystathionine beta-synthase and other proteins. - - - ko:K04767 - - - - ko00000 - - - CBS k141_14395_1 218284.CCDN010000005_gene3406 1.58e-155 441.0 COG0739@1|root,COG0739@2|Bacteria,1TQMQ@1239|Firmicutes,4HC7V@91061|Bacilli,1ZAQT@1386|Bacillus 91061|Bacilli M Peptidase, M23 lytH - - ko:K21472 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_M23 k141_3691_1 218284.CCDN010000002_gene2377 7.56e-56 192.0 COG0843@1|root,COG0843@2|Bacteria,1UNPR@1239|Firmicutes,4HDMA@91061|Bacilli,1ZE3W@1386|Bacillus 91061|Bacilli C Cytochrome C and Quinol oxidase polypeptide I - - 1.9.3.1 ko:K02274 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6 - - COX1 k141_3691_2 218284.CCDN010000002_gene2376 1.03e-30 113.0 COG1845@1|root,COG1845@2|Bacteria,1UBY1@1239|Firmicutes,4INDT@91061|Bacilli,1ZNBG@1386|Bacillus 91061|Bacilli C Cytochrome c oxidase subunit III - - - - - - - - - - - - COX3 k141_27413_1 1131730.BAVI_16197 6.15e-61 201.0 COG0477@1|root,COG2814@2|Bacteria,1TSFM@1239|Firmicutes,4HABN@91061|Bacilli,1ZS92@1386|Bacillus 91061|Bacilli EGP COG0477 Permeases of the major facilitator superfamily yqjV - - - - - - - - - - - MFS_1,MFS_1_like,Sugar_tr k141_26295_1 1347086.CCBA010000025_gene3151 2.26e-29 107.0 29S0I@1|root,30D4V@2|Bacteria,1UAUQ@1239|Firmicutes,4IM7I@91061|Bacilli,1ZJEH@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_26295_2 218284.CCDN010000002_gene2915 3.61e-54 184.0 COG0661@1|root,COG0661@2|Bacteria,1TPIV@1239|Firmicutes,4HBW3@91061|Bacilli,1ZBPH@1386|Bacillus 91061|Bacilli S ABC1 family ubiB - - - - - - - - - - - ABC1,APH,RIO1 k141_16731_1 218284.CCDN010000001_gene1592 1.57e-82 251.0 COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4H9PZ@91061|Bacilli,1ZC9B@1386|Bacillus 91061|Bacilli EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components dppC - - ko:K16201 ko02010,map02010 M00566 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.2 - - BPD_transp_1,OppC_N k141_16731_2 218284.CCDN010000001_gene1591 2.38e-14 71.6 COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,4HA4E@91061|Bacilli,1ZB72@1386|Bacillus 91061|Bacilli P Belongs to the ABC transporter superfamily dppD - - ko:K16202 ko02010,map02010 M00566 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.2 - - ABC_tran,oligo_HPY k141_6071_1 218284.CCDN010000006_gene3670 2.18e-08 55.1 COG0793@1|root,COG0793@2|Bacteria,1TPBI@1239|Firmicutes,4HAKE@91061|Bacilli,1ZBDE@1386|Bacillus 91061|Bacilli M Belongs to the peptidase S41A family ctpB GO:0003674,GO:0003824,GO:0004175,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008233,GO:0009653,GO:0009987,GO:0016787,GO:0019538,GO:0023052,GO:0030154,GO:0030288,GO:0030313,GO:0030435,GO:0031975,GO:0032502,GO:0033218,GO:0034641,GO:0042277,GO:0042597,GO:0042802,GO:0042803,GO:0043170,GO:0043603,GO:0043900,GO:0043902,GO:0043934,GO:0044237,GO:0044238,GO:0044464,GO:0046983,GO:0048518,GO:0048522,GO:0048646,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070011,GO:0071704,GO:0140096,GO:1900190,GO:1900192,GO:1901564 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - PDZ,PDZ_2,PG_binding_1,Peptidase_S41 k141_29808_2 95619.PM1_0230290 4.67e-26 105.0 COG1278@1|root,COG3326@1|root,COG1278@2|Bacteria,COG3326@2|Bacteria,1N6YM@1224|Proteobacteria 1224|Proteobacteria K Cold shock - - - - - - - - - - - - CSD,DUF1294 k141_17980_2 203122.Sde_0760 4.82e-79 268.0 COG0308@1|root,COG0308@2|Bacteria,1PJTM@1224|Proteobacteria,1SYS3@1236|Gammaproteobacteria,4672R@72275|Alteromonadaceae 1236|Gammaproteobacteria E Peptidase family M1 domain - - 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - ERAP1_C,Peptidase_M1 k141_14396_1 1042377.AFPJ01000009_gene193 3.25e-103 322.0 COG3568@1|root,COG3568@2|Bacteria,1R977@1224|Proteobacteria,1RTF2@1236|Gammaproteobacteria,466AF@72275|Alteromonadaceae 1236|Gammaproteobacteria L Type I phosphodiesterase / nucleotide pyrophosphatase - - - - - - - - - - - - Exo_endo_phos,Phosphodiest k141_31030_1 1279017.AQYJ01000021_gene2897 5.98e-201 568.0 COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,1RMB0@1236|Gammaproteobacteria,4648V@72275|Alteromonadaceae 1236|Gammaproteobacteria H Belongs to the folylpolyglutamate synthase family folC GO:0003674,GO:0003824,GO:0004326,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006761,GO:0006807,GO:0008150,GO:0008152,GO:0008841,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046452,GO:0046483,GO:0046900,GO:0046901,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_1997,iSDY_1059.SDY_2514 Mur_ligase_C,Mur_ligase_M k141_31030_2 1042377.AFPJ01000037_gene2994 1.21e-29 113.0 COG3147@1|root,COG3147@2|Bacteria,1NGE3@1224|Proteobacteria,1SCGC@1236|Gammaproteobacteria,46CSJ@72275|Alteromonadaceae 1236|Gammaproteobacteria S Sporulation related domain dedD - - ko:K03749 - - - - ko00000 - - - SPOR k141_34592_1 1294265.JCM21738_2966 3.84e-23 89.4 2EH05@1|root,33AS7@2|Bacteria,1VQFB@1239|Firmicutes,4HS5P@91061|Bacilli,1ZIHY@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_34592_2 1294265.JCM21738_2967 1.5e-92 271.0 COG0783@1|root,COG0783@2|Bacteria,1VCVJ@1239|Firmicutes,4HMBD@91061|Bacilli,1ZGCM@1386|Bacillus 91061|Bacilli P Belongs to the Dps family dps1 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0097159,GO:1901363 - ko:K04047 - - - - ko00000,ko03036 - - - Ferritin k141_9604_2 665952.HMPREF1015_00356 4.27e-10 57.8 2A1KA@1|root,30PU9@2|Bacteria,1UB4E@1239|Firmicutes,4IMH0@91061|Bacilli,1ZK4Y@1386|Bacillus 91061|Bacilli S YrhC-like protein - - - - - - - - - - - - YrhC k141_20283_1 1294265.JCM21738_2243 1.01e-24 101.0 COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,4HAG1@91061|Bacilli,1ZARG@1386|Bacillus 91061|Bacilli J Belongs to the class-I aminoacyl-tRNA synthetase family leuS GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Anticodon_1,tRNA-synt_1,tRNA-synt_1_2 k141_21544_1 218284.CCDN010000001_gene1888 3.8e-132 395.0 COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,4HA8S@91061|Bacilli,1ZBWA@1386|Bacillus 91061|Bacilli J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,IF-2,IF2_N k141_33386_1 265729.GS18_0210650 4.39e-132 383.0 COG1680@1|root,COG1680@2|Bacteria,1TYVU@1239|Firmicutes,4HE5K@91061|Bacilli,1ZCMW@1386|Bacillus 91061|Bacilli V Beta-lactamase - - - - - - - - - - - - Beta-lactamase k141_22708_2 218284.CCDN010000001_gene1728 9.78e-26 97.1 2E7S8@1|root,3327E@2|Bacteria,1VGU6@1239|Firmicutes,4HQVC@91061|Bacilli,1ZJ5I@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_4874_1 218284.CCDN010000001_gene204 2.05e-78 238.0 COG1136@1|root,COG1136@2|Bacteria,1V3HH@1239|Firmicutes,4HHE3@91061|Bacilli,1ZE0V@1386|Bacillus 91061|Bacilli V ABC transporter - - - ko:K02068 - M00211 - - ko00000,ko00002,ko02000 - - - ABC_tran k141_35747_2 1538804.A0A088F7T7_9CAUD 5.76e-280 776.0 4QH10@10239|Viruses,4QSY9@28883|Caudovirales,4QMA5@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k141_35747_3 1538804.A0A088FAG1_9CAUD 4.93e-152 449.0 4QB49@10239|Viruses,4QPU2@28883|Caudovirales,4QKRQ@10699|Siphoviridae 10699|Siphoviridae S Domain of unknown function (DUF4055) - - - - - - - - - - - - - k141_35747_5 1175654.A0A0S0N8X0_9CAUD 1.59e-91 295.0 4QC5Z@10239|Viruses,4QUNP@35237|dsDNA viruses no RNA stage,4QPGX@28883|Caudovirales,4QKMB@10699|Siphoviridae 10699|Siphoviridae S Phage Mu protein F like protein - GO:0005575,GO:0019012,GO:0019028,GO:0044423,GO:0046729 - - - - - - - - - - - k141_35747_6 1175654.A0A0S0NAM4_9CAUD 7.15e-82 254.0 4QE7U@10239|Viruses,4QVF9@35237|dsDNA viruses no RNA stage,4QUEK@28883|Caudovirales,4QNAT@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k141_35747_7 1175654.A0A0S0N2Q7_9CAUD 6.84e-156 448.0 4QFB4@10239|Viruses,4QZ8P@35237|dsDNA viruses no RNA stage,4QSGK@28883|Caudovirales,4QKUP@10699|Siphoviridae 10699|Siphoviridae S viral capsid - - - - - - - - - - - - - k141_35747_9 1300345.LF41_2436 2.39e-27 107.0 2D485@1|root,32TGJ@2|Bacteria,1PBDU@1224|Proteobacteria,1S02H@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_35747_13 1548905.A0A0A1IVS4_9CAUD 1.79e-136 396.0 4QH9I@10239|Viruses,4QTW6@28883|Caudovirales,4QMZW@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k141_35747_15 1548905.A0A0A1IUN7_9CAUD 2.24e-143 447.0 4QF9I@10239|Viruses,4QTTB@28883|Caudovirales,4QN6Q@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k141_36924_1 745411.B3C1_01370 0.0 1146.0 COG2366@1|root,COG2366@2|Bacteria,1MVMH@1224|Proteobacteria,1RMPX@1236|Gammaproteobacteria,1J8DH@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S related to penicillin acylase - - 3.5.1.97 ko:K07116 - - - - ko00000,ko01000 - - - Penicil_amidase k141_10778_1 1219076.N646_0565 5.74e-31 114.0 COG3381@1|root,COG3381@2|Bacteria,1MWWM@1224|Proteobacteria,1S449@1236|Gammaproteobacteria,1XVDD@135623|Vibrionales 135623|Vibrionales S component of anaerobic dehydrogenases - - - - - - - - - - - - Nitrate_red_del k141_10778_2 1116375.VEJY3_07215 1.38e-314 862.0 COG1145@1|root,COG1145@2|Bacteria,1MWHY@1224|Proteobacteria,1RP5W@1236|Gammaproteobacteria,1XTHA@135623|Vibrionales 135623|Vibrionales C 4Fe-4S dicluster domain - - - - - - - - - - - - Fer4,Fer4_7 k141_2499_1 287986.DV20_28585 1.73e-39 142.0 COG1011@1|root,COG1011@2|Bacteria,2IBB1@201174|Actinobacteria,4E7YD@85010|Pseudonocardiales 201174|Actinobacteria S Haloacid dehalogenase-like hydrolase - - 3.8.1.2 ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 - R05287 RC00697 ko00000,ko00001,ko01000 - - - HAD_2 k141_2499_2 608538.HTH_0878 9.37e-05 45.8 COG2452@1|root,COG2452@2|Bacteria,2G48G@200783|Aquificae 200783|Aquificae L PFAM Resolvase, N terminal domain - - - - - - - - - - - - HTH_17,MerR_1,Resolvase k141_2499_3 644282.Deba_0614 2.34e-08 55.5 COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,42MCE@68525|delta/epsilon subdivisions,2WIYP@28221|Deltaproteobacteria 28221|Deltaproteobacteria M PFAM Glycosyl transferase family 2 - - 2.4.2.53 ko:K10012 ko00520,ko01503,map00520,map01503 M00721,M00761 R07661 RC00005,RC02954 ko00000,ko00001,ko00002,ko01000,ko01005,ko02000 4.D.2.1.8 GT2 - Glycos_transf_2 k141_13218_1 1348635.BBJY01000003_gene3909 1.19e-206 578.0 COG1929@1|root,COG1929@2|Bacteria,1MVG9@1224|Proteobacteria,1RMC6@1236|Gammaproteobacteria,1XSHV@135623|Vibrionales 135623|Vibrionales G Belongs to the glycerate kinase type-1 family glxK - 2.7.1.165 ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 - R08572 RC00002,RC00428 ko00000,ko00001,ko01000 - - - Gly_kinase k141_13218_2 1116375.VEJY3_18291 0.0 878.0 COG2610@1|root,COG2610@2|Bacteria,1MUFG@1224|Proteobacteria,1RNGE@1236|Gammaproteobacteria,1XVND@135623|Vibrionales 135623|Vibrionales EG COG2610 H gluconate symporter and related permeases - - - ko:K03299 - - - - ko00000,ko02000 2.A.8 - - GntP_permease k141_13218_3 1116375.VEJY3_18286 8.08e-186 516.0 COG3622@1|root,COG3622@2|Bacteria,1MV53@1224|Proteobacteria,1RQF9@1236|Gammaproteobacteria,1XTG3@135623|Vibrionales 135623|Vibrionales G Belongs to the hyi family - - 5.3.1.35 ko:K22131 - - - - ko00000,ko01000 - - - AP_endonuc_2 k141_13218_4 1116375.VEJY3_18281 1.38e-142 403.0 COG0235@1|root,COG0235@2|Bacteria,1MW7B@1224|Proteobacteria,1RS8X@1236|Gammaproteobacteria,1XVYB@135623|Vibrionales 135623|Vibrionales G Class II Aldolase and Adducin N-terminal domain - - 4.1.1.104 ko:K22130 - - - - ko00000,ko01000 - - - Aldolase_II k141_13218_5 1116375.VEJY3_18276 8.78e-282 772.0 COG3395@1|root,COG3395@2|Bacteria,1MW4G@1224|Proteobacteria,1RN8I@1236|Gammaproteobacteria,1XV5M@135623|Vibrionales 135623|Vibrionales S Putative nucleotide-binding of sugar-metabolising enzyme - - 2.7.1.217 ko:K21948 - - R11706,R11707 - ko00000,ko01000 - - - DUF1357_C,DUF1537 k141_13218_6 1116375.VEJY3_18271 1.07e-190 532.0 COG2084@1|root,COG2084@2|Bacteria,1MUD0@1224|Proteobacteria,1RQXA@1236|Gammaproteobacteria,1XT03@135623|Vibrionales 135623|Vibrionales I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - 1.1.1.411 ko:K08319 - - - - ko00000,ko01000 - - - NAD_binding_11,NAD_binding_2 k141_13218_7 1116375.VEJY3_18266 1.71e-164 462.0 COG1349@1|root,COG1349@2|Bacteria,1MUJG@1224|Proteobacteria,1RQW3@1236|Gammaproteobacteria,1XVBX@135623|Vibrionales 135623|Vibrionales K DeoR C terminal sensor domain - - - - - - - - - - - - DeoRC,HTH_DeoR k141_9917_3 1279017.AQYJ01000028_gene2158 7.01e-89 267.0 COG0212@1|root,COG0212@2|Bacteria,1MZG0@1224|Proteobacteria,1S612@1236|Gammaproteobacteria,467AN@72275|Alteromonadaceae 1236|Gammaproteobacteria H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family ygfA GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0022611,GO:0030272,GO:0032502,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.2 ko:K01934 ko00670,ko01100,map00670,map01100 - R02301 RC00183 ko00000,ko00001,ko01000 - - iECABU_c1320.ECABU_c31940,iECOK1_1307.ECOK1_3298,iECSF_1327.ECSF_2705,iUTI89_1310.UTI89_C3298 5-FTHF_cyc-lig k141_15834_1 218284.CCDN010000001_gene197 3.89e-67 213.0 COG0598@1|root,COG0598@2|Bacteria,1TPSV@1239|Firmicutes,4HAPC@91061|Bacilli,1ZBVW@1386|Bacillus 91061|Bacilli P Mediates influx of magnesium ions corA - - ko:K03284 - - - - ko00000,ko02000 1.A.35.1,1.A.35.3 - - CorA k141_13560_1 345219.Bcoa_2093 7.71e-11 60.8 COG0512@1|root,COG0512@2|Bacteria,1TT9R@1239|Firmicutes,4H9XP@91061|Bacilli,1ZBB7@1386|Bacillus 91061|Bacilli EH Anthranilate synthase trpG - 4.1.3.27 ko:K01658 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - GATase k141_13560_2 665952.HMPREF1015_02332 1.77e-55 189.0 COG0512@1|root,COG0547@1|root,COG0512@2|Bacteria,COG0547@2|Bacteria,1TP8U@1239|Firmicutes,4H9KQ@91061|Bacilli,1ZBZ1@1386|Bacillus 91061|Bacilli E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) trpD GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0004425,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R00985,R00986,R01073 RC00010,RC00440,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Glycos_trans_3N,Glycos_transf_3 k141_6435_1 218284.CCDN010000006_gene3623 3.92e-106 334.0 COG0457@1|root,COG0457@2|Bacteria,1TSH7@1239|Firmicutes,4HACN@91061|Bacilli,1ZBDH@1386|Bacillus 91061|Bacilli M Tetratricopeptide repeat - - - - - - - - - - - - - k141_20525_1 946235.CAER01000043_gene1750 5.08e-23 93.2 2E4BW@1|root,32Z7G@2|Bacteria,1VH0F@1239|Firmicutes,4HPQD@91061|Bacilli,23N09@182709|Oceanobacillus 91061|Bacilli S Protein of unknown function (DUF2512) ycbP - - - - - - - - - - - DUF2512 k141_20525_2 218284.CCDN010000001_gene1650 4.74e-114 335.0 COG1028@1|root,COG1028@2|Bacteria,1TQ80@1239|Firmicutes,4HASE@91061|Bacilli,1ZD1G@1386|Bacillus 91061|Bacilli IQ Enoyl-(Acyl carrier protein) reductase - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 k141_20525_3 1385511.N783_10005 3.32e-41 142.0 COG0664@1|root,COG0664@2|Bacteria,1TTDW@1239|Firmicutes,4I42Q@91061|Bacilli,2YBHI@289201|Pontibacillus 91061|Bacilli K helix_turn_helix, cAMP Regulatory protein - - - - - - - - - - - - HTH_Crp_2,cNMP_binding k141_18260_1 1294265.JCM21738_4040 9.04e-139 399.0 COG0707@1|root,COG0707@2|Bacteria,1TQFT@1239|Firmicutes,4HBAQ@91061|Bacilli,1ZBA5@1386|Bacillus 91061|Bacilli M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) murG - 2.4.1.227 ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 - R05032,R05662 RC00005,RC00049 ko00000,ko00001,ko01000,ko01011 - GT28 - Glyco_tran_28_C,Glyco_transf_28 k141_37155_2 29495.EA26_20400 5.71e-150 434.0 COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,1RMWS@1236|Gammaproteobacteria,1XTI6@135623|Vibrionales 135623|Vibrionales F bifunctional purine biosynthesis protein purh purH GO:0003674,GO:0003824,GO:0004643,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 - - - AICARFT_IMPCHas,MGS k141_1518_1 754035.Mesau_01487 0.000103 49.3 COG1309@1|root,COG1309@2|Bacteria,1RDM7@1224|Proteobacteria,2U83S@28211|Alphaproteobacteria,43HPZ@69277|Phyllobacteriaceae 28211|Alphaproteobacteria K BetI-type transcriptional repressor, C-terminal - - - ko:K02167 - - - - ko00000,ko03000 - - - TetR_C_6,TetR_N k141_1518_2 95619.PM1_0230740 9.52e-119 358.0 COG1902@1|root,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,1RR6H@1236|Gammaproteobacteria 1236|Gammaproteobacteria C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family - - - - - - - - - - - - Oxidored_FMN k141_1518_3 493475.GARC_1965 2.46e-16 77.4 COG3786@1|root,COG3786@2|Bacteria,1RH22@1224|Proteobacteria,1S2SR@1236|Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - YkuD k141_21783_1 997296.PB1_10022 5.15e-43 141.0 COG0694@1|root,COG0694@2|Bacteria,1VAAU@1239|Firmicutes,4HKQ8@91061|Bacilli,1ZHTR@1386|Bacillus 91061|Bacilli O COG0694 Thioredoxin-like proteins and domains yutI - - - - - - - - - - - NifU k141_24121_1 1408303.JNJJ01000007_gene182 1.01e-24 98.6 COG0357@1|root,COG0357@2|Bacteria,1TPBT@1239|Firmicutes,4HAAZ@91061|Bacilli,1ZAWG@1386|Bacillus 91061|Bacilli J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA rsmG GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 ko:K03501 - - - - ko00000,ko01000,ko03009,ko03036 - - - GidB k141_24121_2 1294265.JCM21738_3222 3.77e-70 219.0 COG1475@1|root,COG1475@2|Bacteria,1TP0I@1239|Firmicutes,4HAC6@91061|Bacilli,1ZCDV@1386|Bacillus 91061|Bacilli D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage noc - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc k141_19391_1 218284.CCDN010000005_gene3350 3.43e-74 232.0 COG2200@1|root,COG2200@2|Bacteria,1TQ94@1239|Firmicutes,4HAK1@91061|Bacilli,1ZPXF@1386|Bacillus 91061|Bacilli T Putative diguanylate phosphodiesterase M1-600 - - - - - - - - - - - EAL k141_26728_1 218284.CCDN010000005_gene3415 2.49e-99 298.0 COG2334@1|root,COG2334@2|Bacteria,1VEZ6@1239|Firmicutes,4HBAB@91061|Bacilli,1ZBAM@1386|Bacillus 91061|Bacilli S Spore coat protein yutH GO:0005575,GO:0005623,GO:0042601,GO:0042763,GO:0044464 - - - - - - - - - - - k141_33690_1 1453501.JELR01000002_gene890 2.35e-119 385.0 COG1652@1|root,COG3210@1|root,COG1652@2|Bacteria,COG3210@2|Bacteria,1MXIP@1224|Proteobacteria,1RSAX@1236|Gammaproteobacteria,468YR@72275|Alteromonadaceae 1236|Gammaproteobacteria U haemagglutination activity domain Z012_01725 GO:0005575,GO:0005576 - - - - - - - - - - ESPR,Glug,Haemagg_act k141_8745_1 333138.LQ50_21190 4.05e-60 202.0 COG3119@1|root,COG3119@2|Bacteria,1UDRD@1239|Firmicutes,4HD9J@91061|Bacilli,1ZCSX@1386|Bacillus 91061|Bacilli P Protein of unknown function (DUF229) - - - - - - - - - - - - DUF4976,Sulfatase k141_5122_1 1453501.JELR01000002_gene1157 8.66e-184 514.0 COG0583@1|root,COG0583@2|Bacteria,1MZTA@1224|Proteobacteria,1RN7R@1236|Gammaproteobacteria,464C1@72275|Alteromonadaceae 1236|Gammaproteobacteria K transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_34828_1 439375.Oant_2368 8.07e-23 98.6 COG0524@1|root,COG0524@2|Bacteria,1MVG2@1224|Proteobacteria,2TSDV@28211|Alphaproteobacteria,1J23E@118882|Brucellaceae 28211|Alphaproteobacteria G pfkB family carbohydrate kinase kdgK GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0008673,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0019200,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044262,GO:0046835,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.7.1.45 ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 M00061,M00308,M00631 R01541 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - PfkB k141_37156_1 218284.CCDN010000001_gene1741 1.45e-113 333.0 COG0584@1|root,COG0584@2|Bacteria,1UY23@1239|Firmicutes,4HEAD@91061|Bacilli,1ZCIE@1386|Bacillus 91061|Bacilli C glycerophosphoryl diester phosphodiesterase glpQ - 3.1.3.1,3.1.4.46 ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 M00126 R01030,R01470,R04620 RC00017,RC00425 ko00000,ko00001,ko00002,ko01000 - - - GDPD,PhoD,PhoD_N k141_19392_1 218284.CCDN010000001_gene967 7.13e-122 360.0 COG1570@1|root,COG1570@2|Bacteria,1TP4E@1239|Firmicutes,4HAN2@91061|Bacilli,1ZB5Q@1386|Bacillus 91061|Bacilli L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseA - 3.1.11.6 ko:K03601 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_L,tRNA_anti_2 k141_32368_1 218284.CCDN010000006_gene3585 4.02e-195 548.0 COG0460@1|root,COG0460@2|Bacteria,1TQ2H@1239|Firmicutes,4HBAP@91061|Bacilli,1ZCGH@1386|Bacillus 91061|Bacilli E homoserine dehydrogenase - - 1.1.1.3 ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00017,M00018 R01773,R01775 RC00087 ko00000,ko00001,ko00002,ko01000 - - - Homoserine_dh,NAD_binding_3 k141_9919_1 218284.CCDN010000006_gene3572 1.81e-141 417.0 COG4264@1|root,COG4264@2|Bacteria,1TSC3@1239|Firmicutes,4HDUE@91061|Bacilli,1ZQIZ@1386|Bacillus 91061|Bacilli Q IucA / IucC family - - - - - - - - - - - - FhuF,IucA_IucC k141_13561_1 511.JT27_06670 8.89e-110 318.0 COG1335@1|root,COG1335@2|Bacteria,1MWFQ@1224|Proteobacteria,2VKV5@28216|Betaproteobacteria,3T36H@506|Alcaligenaceae 28216|Betaproteobacteria Q Isochorismatase family ycaC - - - - - - - - - - - Isochorismatase k141_13561_2 745411.B3C1_07591 1.96e-31 125.0 28HF6@1|root,2Z7RB@2|Bacteria,1P254@1224|Proteobacteria,1S4WK@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Alginate export - - - - - - - - - - - - Alginate_exp k141_7468_2 1279017.AQYJ01000026_gene212 1.13e-127 365.0 COG4122@1|root,COG4122@2|Bacteria,1N2AR@1224|Proteobacteria,1S16T@1236|Gammaproteobacteria,4671N@72275|Alteromonadaceae 1236|Gammaproteobacteria S Methyltransferase domain - - - - - - - - - - - - Methyltransf_24 k141_7468_3 1279017.AQYJ01000026_gene213 1.78e-22 95.1 COG3387@1|root,COG3387@2|Bacteria,1NB01@1224|Proteobacteria,1RS3W@1236|Gammaproteobacteria,46581@72275|Alteromonadaceae 1236|Gammaproteobacteria G PFAM Glycoside hydrolase 15-related - - - - - - - - - - - - Prenyltrans k141_9920_1 443255.SCLAV_2684 1.33e-07 58.5 COG4733@1|root,COG4733@2|Bacteria,2HCWC@201174|Actinobacteria 201174|Actinobacteria Q PA14 domain - - - - - - - - - - - - Big_5,Malectin,PA14 k141_34829_1 218284.CCDN010000005_gene3268 8.03e-95 303.0 COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HACY@91061|Bacilli,1ZB8K@1386|Bacillus 91061|Bacilli O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE clpB GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564 - ko:K03695 ko04213,map04213 - - - ko00000,ko00001,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N k141_20527_1 666686.B1NLA3E_04990 4.64e-62 200.0 COG4641@1|root,COG4641@2|Bacteria,1UWN6@1239|Firmicutes,4HAGV@91061|Bacilli,1ZEYP@1386|Bacillus 91061|Bacilli S Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_trans_1_2 k141_19394_1 1460634.JCM19037_1578 1.64e-16 75.5 2ERWU@1|root,33JFZ@2|Bacteria,1VNMJ@1239|Firmicutes,4HS0J@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - Peptidase_M78 k141_33692_1 1004785.AMBLS11_01855 1.27e-124 371.0 COG2356@1|root,COG2356@2|Bacteria,1R4W1@1224|Proteobacteria,1RPZG@1236|Gammaproteobacteria,46CMU@72275|Alteromonadaceae 1236|Gammaproteobacteria L Endonuclease I - - - - - - - - - - - - CBM_4_9,Endonuclease_1 k141_9921_2 1279017.AQYJ01000024_gene1198 2.76e-54 171.0 COG2963@1|root,COG2963@2|Bacteria,1N3E0@1224|Proteobacteria,1S9T7@1236|Gammaproteobacteria,46847@72275|Alteromonadaceae 1236|Gammaproteobacteria L Helix-turn-helix domain - - - ko:K07483 - - - - ko00000 - - - HTH_Tnp_1 k141_5123_1 218284.CCDN010000001_gene1970 2.14e-211 596.0 COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TYUA@1239|Firmicutes,4HDKK@91061|Bacilli,1ZPXC@1386|Bacillus 91061|Bacilli T helix_turn_helix, arabinose operon control protein ntrC - - ko:K07720 ko02020,map02020 M00519 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_18,Response_reg k141_14610_1 395495.Lcho_3323 1.33e-41 151.0 COG0366@1|root,COG0366@2|Bacteria,1MVKX@1224|Proteobacteria,2VHW5@28216|Betaproteobacteria,1KN4Y@119065|unclassified Burkholderiales 28216|Betaproteobacteria G Alpha amylase catalytic region - - 3.2.1.1,3.2.1.10,3.2.1.20,3.2.1.93,5.4.99.16 ko:K01182,ko:K01187,ko:K01226,ko:K05343 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00028,R00801,R00802,R00837,R01557,R01718,R01791,R02108,R02112,R06087,R06088,R06113,R06199,R11262 RC00028,RC00049,RC00059,RC00077,RC00451,RC01816 ko00000,ko00001,ko01000 - GH13,GH31 - Alpha-amylase,Malt_amylase_C k141_37158_1 323850.Shew_0927 4.45e-94 291.0 COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,1RNB7@1236|Gammaproteobacteria,2Q9PB@267890|Shewanellaceae 1236|Gammaproteobacteria S PFAM Amidohydrolase 3 - - - - - - - - - - - - Amidohydro_3 k141_19423_4 1116375.VEJY3_12280 3.54e-123 353.0 COG2802@1|root,COG2802@2|Bacteria,1MYN2@1224|Proteobacteria,1S7UF@1236|Gammaproteobacteria,1XWU4@135623|Vibrionales 135623|Vibrionales S to the N-terminal domain of Lon protease - - - ko:K07157 - - - - ko00000 - - - LON_substr_bdg k141_19423_5 1116375.VEJY3_12275 2.54e-259 718.0 COG1653@1|root,COG1653@2|Bacteria,1R5TB@1224|Proteobacteria,1RSBF@1236|Gammaproteobacteria,1XU4X@135623|Vibrionales 135623|Vibrionales G Domain of unknown function (DUF4397) - - - - - - - - - - - - DUF4397 k141_19423_6 1219076.N646_1475 3.61e-132 375.0 COG1595@1|root,COG1595@2|Bacteria,1RHRR@1224|Proteobacteria,1S2UD@1236|Gammaproteobacteria,1XTWN@135623|Vibrionales 135623|Vibrionales K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4,Sigma70_r4_2 k141_19423_7 1116375.VEJY3_12265 4.76e-112 325.0 COG3806@1|root,COG3806@2|Bacteria,1MYHP@1224|Proteobacteria,1S8F3@1236|Gammaproteobacteria,1XVBP@135623|Vibrionales 135623|Vibrionales T COG3806 Anti-sigma factor - - - ko:K07167 - - - - ko00000 - - - Cupin_7,zf-HC2 k141_15844_1 1279017.AQYJ01000024_gene878 0.0 904.0 COG0591@1|root,COG4191@1|root,COG0591@2|Bacteria,COG4191@2|Bacteria,1QTSW@1224|Proteobacteria,1T1G2@1236|Gammaproteobacteria,4643M@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0591 Na proline symporter cbrA - - - - - - - - - - - HATPase_c,HisKA,PAS k141_15844_3 1073999.BN137_3016 1.46e-08 57.8 COG0008@1|root,COG0008@2|Bacteria,1MUN7@1224|Proteobacteria,1RMYQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon gluQ GO:0000166,GO:0002097,GO:0003674,GO:0005488,GO:0005524,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 - ko:K01894 - - - - ko00000,ko01000,ko01007,ko03016 - - - tRNA-synt_1c k141_20558_1 493475.GARC_4045 7.98e-69 230.0 COG4773@1|root,COG4773@2|Bacteria,1QTXJ@1224|Proteobacteria,1T2BS@1236|Gammaproteobacteria,46D93@72275|Alteromonadaceae 1236|Gammaproteobacteria P TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_20558_2 1462527.CCDM010000001_gene2520 1.68e-07 54.7 COG1292@1|root,COG1292@2|Bacteria,1TRS6@1239|Firmicutes,4HA7U@91061|Bacilli,23JX1@182709|Oceanobacillus 91061|Bacilli M BCCT, betaine/carnitine/choline family transporter - - - ko:K03451 - - - - ko00000 2.A.15 - - BCCT k141_12418_2 218284.CCDN010000010_gene4392 2.93e-113 333.0 COG1623@1|root,COG1623@2|Bacteria,1TQD8@1239|Firmicutes,4HAQP@91061|Bacilli,1ZBIY@1386|Bacillus 91061|Bacilli L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation disA - 2.7.7.85 ko:K07067 - - - - ko00000,ko01000 - - - DisA-linker,DisA_N,HHH,HHH_2 k141_8789_1 218284.CCDN010000001_gene696 8.25e-118 343.0 COG0826@1|root,COG0826@2|Bacteria,1TQIZ@1239|Firmicutes,4HA2T@91061|Bacilli,1ZAXB@1386|Bacillus 91061|Bacilli O Peptidase U32 yrrN - - ko:K08303 ko05120,map05120 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_U32 k141_18300_1 1385935.N836_18245 2.23e-09 58.2 COG0577@1|root,COG0577@2|Bacteria,1G0Z7@1117|Cyanobacteria,1H9BF@1150|Oscillatoriales 1117|Cyanobacteria V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD k141_18300_2 1123237.Salmuc_03212 1.76e-12 73.2 COG0845@1|root,COG0845@2|Bacteria,1Q10W@1224|Proteobacteria,2TSC8@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Efflux transporter, RND family, MFP subunit - - - ko:K02005 - - - - ko00000 - - - HlyD_3 k141_7488_1 1122599.AUGR01000001_gene268 1.99e-133 399.0 COG0446@1|root,COG0446@2|Bacteria,1MXA9@1224|Proteobacteria,1RSF2@1236|Gammaproteobacteria,1XIZF@135619|Oceanospirillales 135619|Oceanospirillales C BFD-like [2Fe-2S] binding domain - - - - - - - - - - - - Fer2_BFD,Pyr_redox_2 k141_7488_2 296591.Bpro_4375 3.93e-23 93.6 COG3383@1|root,COG3383@2|Bacteria,1QUPZ@1224|Proteobacteria 1224|Proteobacteria C 2Fe-2S iron-sulfur cluster binding domain - - - - - - - - - - - - Fer2_4 k141_7488_3 935840.JAEQ01000006_gene2581 3.53e-113 341.0 COG0665@1|root,COG0665@2|Bacteria,1MVG3@1224|Proteobacteria,2TRYR@28211|Alphaproteobacteria,43MV1@69277|Phyllobacteriaceae 28211|Alphaproteobacteria E FAD dependent oxidoreductase - - - - - - - - - - - - DAO k141_7488_4 511062.GU3_13705 5.33e-66 209.0 COG0834@1|root,COG0834@2|Bacteria,1NT2J@1224|Proteobacteria,1S077@1236|Gammaproteobacteria,1Y541@135624|Aeromonadales 135624|Aeromonadales ET Belongs to the bacterial solute-binding protein 3 family - - - ko:K10022 ko02010,map02010 M00235 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.11 - - SBP_bac_3 k141_21805_1 675812.VHA_001614 3.04e-12 68.6 COG1943@1|root,COG1943@2|Bacteria,1MVUV@1224|Proteobacteria,1RNIV@1236|Gammaproteobacteria,1XTXM@135623|Vibrionales 135623|Vibrionales L COG1943 Transposase and inactivated derivatives - - - - - - - - - - - - - k141_21805_2 1117314.PCIT_00025 3.46e-19 83.2 COG1943@1|root,COG1943@2|Bacteria,1MVUV@1224|Proteobacteria,1RNIV@1236|Gammaproteobacteria,2Q0NQ@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria L COG1943 Transposase and inactivated derivatives - - - - - - - - - - - - - k141_31292_1 1397696.KK211189_gene41 7.38e-46 155.0 COG0395@1|root,COG0395@2|Bacteria,1TS0R@1239|Firmicutes,4HAIE@91061|Bacilli,3WEDE@539002|Bacillales incertae sedis 91061|Bacilli G Binding-protein-dependent transport system inner membrane component - - - ko:K02026,ko:K10190 ko02010,map02010 M00199,M00207 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.4 - - BPD_transp_1 k141_25402_1 866895.HBHAL_1943 3.87e-41 148.0 COG0591@1|root,COG0591@2|Bacteria,1U5X8@1239|Firmicutes,4HD7K@91061|Bacilli,3NEGB@45667|Halobacillus 91061|Bacilli E Sodium:solute symporter family putP_2 - - ko:K03307 - - - - ko00000 2.A.21 - - SSF k141_32388_2 218284.CCDN010000001_gene1121 1.98e-196 554.0 COG0457@1|root,COG0457@2|Bacteria,1TT97@1239|Firmicutes,4HAIA@91061|Bacilli,1ZAZM@1386|Bacillus 91061|Bacilli S COG0457 FOG TPR repeat ypiA - - - - - - - - - - - TPR_16,TPR_19,TPR_2,TPR_7,TPR_8 k141_9948_1 1042377.AFPJ01000015_gene1610 1.79e-102 306.0 COG0604@1|root,COG0604@2|Bacteria,1QY04@1224|Proteobacteria,1RSP0@1236|Gammaproteobacteria,46BBM@72275|Alteromonadaceae 1236|Gammaproteobacteria C Zinc-binding dehydrogenase - - 1.1.1.1 ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N,ADH_zinc_N_2,KR,PP-binding,PS-DH k141_19424_1 1535422.ND16A_0329 3.19e-93 302.0 COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,1SP6I@1236|Gammaproteobacteria,2Q6G6@267889|Colwelliaceae 1236|Gammaproteobacteria P Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family cusA - - ko:K07787 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.6.1.4 - - ACR_tran k141_11115_1 1116375.VEJY3_12665 2.06e-178 499.0 COG4785@1|root,COG4785@2|Bacteria,1N02Y@1224|Proteobacteria,1RP8P@1236|Gammaproteobacteria,1XT95@135623|Vibrionales 135623|Vibrionales M May be involved in cell division nlpI - - ko:K05803 - - - - ko00000 - - - TPR_8 k141_33724_2 1042377.AFPJ01000007_gene1890 1e-120 356.0 COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,1RMP9@1236|Gammaproteobacteria,4649Y@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG4591 ABC-type transport system, involved in lipoprotein release, permease component lolC - - ko:K09808 ko02010,map02010 M00255 - - ko00000,ko00001,ko00002,ko02000 3.A.1.125 - - FtsX,MacB_PCD k141_12419_2 1453501.JELR01000002_gene129 3.8e-69 222.0 COG3203@1|root,COG3203@2|Bacteria,1MX4Q@1224|Proteobacteria,1RY5B@1236|Gammaproteobacteria,4654M@72275|Alteromonadaceae 1236|Gammaproteobacteria M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - - - - - - - - - - Porin_2 k141_15845_2 1178482.BJB45_07290 2.78e-32 118.0 COG1349@1|root,COG1349@2|Bacteria,1MUJG@1224|Proteobacteria,1RPS0@1236|Gammaproteobacteria,1XIJ3@135619|Oceanospirillales 135619|Oceanospirillales K Represses the glpD, glpFK, glpTQ, and glpACB operons involved in glycerol-3-phosphate metabolism glpR - - ko:K02444 - - - - ko00000,ko03000 - - - DeoRC,HTH_DeoR k141_21806_1 686340.Metal_3078 7.89e-23 98.6 COG1073@1|root,COG1073@2|Bacteria,1R8S6@1224|Proteobacteria,1S4WS@1236|Gammaproteobacteria,1XGDM@135618|Methylococcales 135618|Methylococcales S Alpha/beta hydrolase family - - - - - - - - - - - - - k141_30020_1 1042377.AFPJ01000004_gene406 2.85e-134 407.0 COG1629@1|root,COG4771@2|Bacteria,1MUWN@1224|Proteobacteria,1RN1E@1236|Gammaproteobacteria,464FG@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec k141_27613_2 1042377.AFPJ01000043_gene880 7.99e-16 74.7 COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,1RMJJ@1236|Gammaproteobacteria,465VY@72275|Alteromonadaceae 1236|Gammaproteobacteria KT Response regulator of the LytR AlgR family - - - ko:K02477 - - - - ko00000,ko02022 - - - LytTR,Response_reg k141_4054_1 1294265.JCM21738_2580 1.66e-132 379.0 COG2267@1|root,COG2267@2|Bacteria,1UZM1@1239|Firmicutes,4HFJW@91061|Bacilli,1ZD5F@1386|Bacillus 91061|Bacilli I carboxylic ester hydrolase activity yjaU - - - - - - - - - - - Hydrolase_4 k141_20560_2 218284.CCDN010000006_gene3680 1.56e-97 290.0 COG2177@1|root,COG2177@2|Bacteria,1TPND@1239|Firmicutes,4HA5A@91061|Bacilli,1ZC4Q@1386|Bacillus 91061|Bacilli D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation ftsX GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0007154,GO:0007165,GO:0007166,GO:0008150,GO:0008356,GO:0009966,GO:0009987,GO:0010033,GO:0010646,GO:0016020,GO:0016043,GO:0019221,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0023052,GO:0032506,GO:0034097,GO:0042173,GO:0042221,GO:0043937,GO:0043938,GO:0044085,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051301,GO:0051716,GO:0065007,GO:0070098,GO:0070297,GO:0070887,GO:0071310,GO:0071345,GO:0071840,GO:0071944,GO:0090529,GO:1902531 - ko:K09811 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - FtsX k141_5157_1 1453501.JELR01000001_gene1805 4.69e-111 331.0 COG0208@1|root,COG0208@2|Bacteria,1MWUS@1224|Proteobacteria,1RMJC@1236|Gammaproteobacteria,4649Z@72275|Alteromonadaceae 1236|Gammaproteobacteria F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdB - 1.17.4.1 ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - iJN746.PP_1177 Ribonuc_red_sm k141_17041_1 1279017.AQYJ01000019_gene1473 4.5e-77 231.0 COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,1S3QK@1236|Gammaproteobacteria,466UW@72275|Alteromonadaceae 1236|Gammaproteobacteria J Ribosomal protein L17 rplQ GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02879 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L17 k141_17041_3 349521.HCH_04158 2.43e-10 66.2 2EFH2@1|root,3399N@2|Bacteria,1NE4K@1224|Proteobacteria,1SFCY@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_17041_4 1279017.AQYJ01000019_gene1476 4.06e-286 789.0 COG0657@1|root,COG0657@2|Bacteria,1MVRE@1224|Proteobacteria,1S0ZD@1236|Gammaproteobacteria,468F2@72275|Alteromonadaceae 1236|Gammaproteobacteria I Pectinacetylesterase - - - - - - - - - - - - PAE k141_32389_1 1246484.D479_10846 3.38e-57 179.0 COG1733@1|root,COG1733@2|Bacteria,1VA9M@1239|Firmicutes,4HH0A@91061|Bacilli,3NF5S@45667|Halobacillus 91061|Bacilli K HxlR-like helix-turn-helix - - - - - - - - - - - - HxlR k141_523_1 42565.FP66_02745 2.07e-43 154.0 COG1368@1|root,COG1368@2|Bacteria 2|Bacteria M sulfuric ester hydrolase activity mdoB GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006490,GO:0006629,GO:0008150,GO:0008152,GO:0008960,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0042597,GO:0044237,GO:0044238,GO:0044255,GO:0044464,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576 2.7.8.20 ko:K01002 ko01100,map01100 - - - ko00000,ko01000 - - - Sulfatase k141_523_2 42565.FP66_02750 1.49e-91 272.0 COG0463@1|root,COG0463@2|Bacteria,1RE4C@1224|Proteobacteria,1SJQD@1236|Gammaproteobacteria,1XR8Y@135619|Oceanospirillales 135619|Oceanospirillales M Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 k141_9950_1 218284.CCDN010000006_gene3517 4.01e-23 102.0 COG3263@1|root,COG3263@2|Bacteria,1TQPJ@1239|Firmicutes,4HC8I@91061|Bacilli,1ZC6H@1386|Bacillus 91061|Bacilli P COG3263 NhaP-type Na H and K H antiporters with a unique C-terminal domain cvrA - - ko:K11105 - - - - ko00000,ko02000 2.A.36.6 - - Na_H_Exchanger,TrkA_C k141_9950_2 935837.JAEK01000009_gene3641 2.74e-90 275.0 COG0385@1|root,COG0385@2|Bacteria,1TP85@1239|Firmicutes,4HB6E@91061|Bacilli,1ZQNX@1386|Bacillus 91061|Bacilli S Na -dependent transporter ybaS - - - - - - - - - - - SBF,SBF_like k141_12421_1 1280001.BAOA01000138_gene2050 1.87e-171 483.0 COG1087@1|root,COG1087@2|Bacteria,1MUHI@1224|Proteobacteria,1RMTU@1236|Gammaproteobacteria,1XSCZ@135623|Vibrionales 135623|Vibrionales M udp-glucose 4-epimerase galE - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - GDP_Man_Dehyd k141_12421_2 223926.28809179 1.78e-25 104.0 COG2199@1|root,COG2199@2|Bacteria,1RGCV@1224|Proteobacteria,1T259@1236|Gammaproteobacteria,1XU5C@135623|Vibrionales 135623|Vibrionales T Periplasmic sensor domain - - - - - - - - - - - - CHASE8,GGDEF,HAMP,PAS,PAS_8,PAS_9 k141_2947_1 218284.CCDN010000008_gene4136 1.51e-287 791.0 COG0297@1|root,COG0297@2|Bacteria,1TQ4M@1239|Firmicutes,4HAVA@91061|Bacilli,1ZDBA@1386|Bacillus 91061|Bacilli G Synthesizes alpha-1,4-glucan chains using ADP-glucose glgA GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009011,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 M00565 R02421 RC00005 ko00000,ko00001,ko00002,ko01000,ko01003 - GT5 - Glyco_transf_5,Glycos_transf_1 k141_11482_1 1042377.AFPJ01000012_gene1375 2e-81 249.0 COG2771@1|root,COG2771@2|Bacteria,1QW0I@1224|Proteobacteria,1T5AY@1236|Gammaproteobacteria 1236|Gammaproteobacteria K helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE k141_27057_1 1294265.JCM21738_1265 1.16e-130 376.0 COG3278@1|root,COG3278@2|Bacteria,1V0VX@1239|Firmicutes,4HBC4@91061|Bacilli 91061|Bacilli P Cytochrome C and Quinol oxidase polypeptide I - - - - - - - - - - - - COX1 k141_23352_1 1279017.AQYJ01000021_gene2780 1e-260 723.0 COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,1RP0W@1236|Gammaproteobacteria,465KZ@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor bioA GO:0003674,GO:0003824,GO:0004015,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.6.1.62 ko:K00833 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R03231 RC00006,RC00887 ko00000,ko00001,ko00002,ko01000,ko01007 - - iUTI89_1310.UTI89_C0772,iZ_1308.Z0993 Aminotran_3 k141_23352_2 1279017.AQYJ01000023_gene3275 1.77e-88 271.0 COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,1RNPX@1236|Gammaproteobacteria,464Y1@72275|Alteromonadaceae 1236|Gammaproteobacteria P Belongs to the ABC transporter superfamily fbpC - 3.6.3.30 ko:K02010 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.10 - - ABC_tran,TOBE_2 k141_10335_1 1294265.JCM21738_4835 3.84e-80 246.0 29X3J@1|root,32W55@2|Bacteria,1VAGX@1239|Firmicutes,4HN0C@91061|Bacilli,1ZIZD@1386|Bacillus 91061|Bacilli S Spore coat protein Z - - - - - - - - - - - - Spore-coat_CotZ k141_22032_1 1453501.JELR01000001_gene2114 1.04e-08 55.5 COG3751@1|root,COG3751@2|Bacteria,1NG7K@1224|Proteobacteria,1S7QH@1236|Gammaproteobacteria,466EA@72275|Alteromonadaceae 1236|Gammaproteobacteria O Prolyl 4-hydroxylase alpha subunit homologues. - - 1.14.11.2 ko:K00472 ko00330,ko01100,map00330,map01100 - R01252 RC00478 ko00000,ko00001,ko01000 - - - 2OG-FeII_Oxy_3 k141_22032_2 1453501.JELR01000001_gene2113 1.87e-13 68.2 COG5608@1|root,COG5608@2|Bacteria,1MZF0@1224|Proteobacteria,1SEGD@1236|Gammaproteobacteria,468MK@72275|Alteromonadaceae 1236|Gammaproteobacteria S Late embryogenesis abundant protein - - - - - - - - - - - - LEA_2 k141_25745_1 218284.CCDN010000001_gene1756 2.31e-67 211.0 COG1443@1|root,COG1443@2|Bacteria,1V6SB@1239|Firmicutes,4HJ2T@91061|Bacilli,1ZFNY@1386|Bacillus 91061|Bacilli I COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes M1-740 - - - - - - - - - - - NUDIX k141_14836_1 1279017.AQYJ01000022_gene2601 6.59e-120 348.0 COG1834@1|root,COG1834@2|Bacteria,1R5UT@1224|Proteobacteria,1RYEQ@1236|Gammaproteobacteria,46AEJ@72275|Alteromonadaceae 1236|Gammaproteobacteria E Amidinotransferase - - - - - - - - - - - - Amidinotransf k141_14836_2 1279017.AQYJ01000022_gene2600 1.36e-256 708.0 COG0624@1|root,COG0624@2|Bacteria,1MVUX@1224|Proteobacteria,1RPPD@1236|Gammaproteobacteria 1236|Gammaproteobacteria E the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia - - 3.5.1.6,3.5.1.87 ko:K06016 ko00240,ko01100,map00240,map01100 M00046 R00905,R04666 RC00096 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20,Peptidase_M28 k141_14836_5 1279017.AQYJ01000022_gene2597 1.69e-81 244.0 COG1803@1|root,COG1803@2|Bacteria,1RD3D@1224|Proteobacteria,1S3XN@1236|Gammaproteobacteria,46733@72275|Alteromonadaceae 1236|Gammaproteobacteria G methylglyoxal synthase mgsA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0008150,GO:0008152,GO:0008929,GO:0009058,GO:0009438,GO:0009987,GO:0016829,GO:0016835,GO:0016838,GO:0019242,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0071704,GO:1901576 4.2.3.3 ko:K01734 ko00640,ko01120,map00640,map01120 - R01016 RC00424 ko00000,ko00001,ko01000 - - iECUMN_1333.ECUMN_1153,iYL1228.KPN_00992 MGS k141_14836_6 1279017.AQYJ01000022_gene2596 4.58e-53 170.0 2E5XZ@1|root,330MS@2|Bacteria,1NBN8@1224|Proteobacteria,1SCZT@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_14836_9 1279017.AQYJ01000022_gene2594 3.84e-113 336.0 COG4240@1|root,COG4240@2|Bacteria,1QUTA@1224|Proteobacteria,1T23W@1236|Gammaproteobacteria,466GQ@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG4240 Predicted kinase - - 2.7.1.31 ko:K15918 ko00260,ko00561,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00561,map00630,map01100,map01110,map01130,map01200 M00532 R01514 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - ArgK,PRK k141_16092_2 945550.VISI1226_15756 2.8e-120 355.0 COG4965@1|root,COG4965@2|Bacteria,1MUXK@1224|Proteobacteria,1S1QN@1236|Gammaproteobacteria,1XVM8@135623|Vibrionales 135623|Vibrionales U COG4965 Flp pilus assembly protein TadB - - - ko:K12510 - - - - ko00000,ko02044 - - - T2SSF k141_794_1 1279017.AQYJ01000026_gene224 3.37e-32 124.0 COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,1RQRP@1236|Gammaproteobacteria,4653Y@72275|Alteromonadaceae 1236|Gammaproteobacteria Q COG1228 Imidazolonepropionase and related amidohydrolases - - - - - - - - - - - - Amidohydro_1 k141_794_2 983545.Glaag_0306 2.07e-66 209.0 COG0625@1|root,COG0625@2|Bacteria,1Q05U@1224|Proteobacteria,1RZZS@1236|Gammaproteobacteria,4666H@72275|Alteromonadaceae 1236|Gammaproteobacteria O Glutathione S-transferase - - - - - - - - - - - - GST_C,GST_C_2,GST_N_3 k141_2948_1 218284.CCDN010000001_gene1052 1.58e-16 73.9 COG0454@1|root,COG0456@2|Bacteria,1VAD7@1239|Firmicutes,4HKR2@91061|Bacilli,1ZHDK@1386|Bacillus 91061|Bacilli K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases ribT - - ko:K02859 - - - - ko00000 - - - Acetyltransf_1,Acetyltransf_10 k141_2948_2 218284.CCDN010000001_gene1053 5.96e-52 169.0 COG1547@1|root,COG1547@2|Bacteria,1VBXA@1239|Firmicutes,4HMG9@91061|Bacilli,1ZH3U@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF309) ypuF - - ko:K09763 - - - - ko00000 - - - DUF309 k141_35199_1 218284.CCDN010000001_gene378 2.2e-134 382.0 COG2220@1|root,COG2220@2|Bacteria,1TQR1@1239|Firmicutes,4HBM0@91061|Bacilli,1ZBI0@1386|Bacillus 91061|Bacilli S Belongs to the UPF0173 family ytkL - - - - - - - - - - - Lactamase_B_2,Lactamase_B_3 k141_32627_1 1294265.JCM21738_4775 3.58e-114 328.0 COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,4HAE2@91061|Bacilli,1ZBNI@1386|Bacillus 91061|Bacilli C Electron transfer flavoprotein alpha subunit fixB - - ko:K03522 - - - - ko00000,ko04147 - - - ETF,ETF_alpha k141_32627_2 1294265.JCM21738_4776 4.79e-25 101.0 COG0644@1|root,COG0644@2|Bacteria,1TRRU@1239|Firmicutes,4HBFQ@91061|Bacilli,1ZASH@1386|Bacillus 91061|Bacilli C COG0644 Dehydrogenases (flavoproteins) - - - ko:K00313 - - - - ko00000,ko01000 - - - DAO,FAD_binding_3,FAD_oxidored,HI0933_like,Trp_halogenase k141_33976_1 1453501.JELR01000005_gene1572 3.33e-58 189.0 COG0845@1|root,COG0845@2|Bacteria,1R99C@1224|Proteobacteria,1RZS0@1236|Gammaproteobacteria,46C8U@72275|Alteromonadaceae 1236|Gammaproteobacteria M Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - - - - - - - - - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 k141_33976_2 1042377.AFPJ01000004_gene335 7.22e-14 71.2 COG0845@1|root,COG0845@2|Bacteria,1N97Q@1224|Proteobacteria,1RXZP@1236|Gammaproteobacteria,46BQ3@72275|Alteromonadaceae 1236|Gammaproteobacteria M Multidrug transporter - - - - - - - - - - - - Biotin_lipoyl_2,GAF,HlyD_3,HlyD_D23 k141_18618_1 218284.CCDN010000001_gene1276 3.47e-214 609.0 28RY4@1|root,30CEX@2|Bacteria,1U9S3@1239|Firmicutes,4IJYG@91061|Bacilli,1ZNUD@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_9051_1 1042377.AFPJ01000008_gene1956 2.04e-117 364.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MV8W@1224|Proteobacteria,1RQEQ@1236|Gammaproteobacteria,463XU@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec k141_25746_2 1453501.JELR01000001_gene2702 2.55e-67 215.0 COG0845@1|root,COG0845@2|Bacteria,1PEVY@1224|Proteobacteria,1RPEQ@1236|Gammaproteobacteria,465PN@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - - - - - - - - - - Biotin_lipoyl_2,HlyD_3 k141_12741_1 315730.BcerKBAB4_3533 1.01e-11 69.3 COG1388@1|root,COG3773@1|root,COG1388@2|Bacteria,COG3773@2|Bacteria,1TRFW@1239|Firmicutes,4IPK9@91061|Bacilli,1ZRBM@1386|Bacillus 91061|Bacilli M Cell Wall Hydrolase ykvT - 3.5.1.28 ko:K01449 - - R04112 RC00064,RC00141 ko00000,ko01000 - - - Hydrolase_2,LysM k141_37407_1 1453501.JELR01000001_gene3225 2.86e-138 410.0 COG4656@1|root,COG4656@2|Bacteria,1QTUI@1224|Proteobacteria,1RMIM@1236|Gammaproteobacteria,4655V@72275|Alteromonadaceae 1236|Gammaproteobacteria C Part of a membrane complex involved in electron transport rnfC GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0055114 - ko:K03615 - - - - ko00000 - - - Complex1_51K,Fer4_10,Fer4_7,Fer4_8,RnfC_N,SLBB k141_25784_1 1499689.CCNN01000004_gene307 5.43e-67 213.0 2BJFF@1|root,32DS1@2|Bacteria,1UUR5@1239|Firmicutes,257J8@186801|Clostridia,36T86@31979|Clostridiaceae 186801|Clostridia S Intron-encoded nuclease repeat 2 - - - - - - - - - - - - - k141_2970_1 1042377.AFPJ01000042_gene1016 6.4e-74 248.0 COG1629@1|root,COG4771@2|Bacteria,1QV5Q@1224|Proteobacteria,1T4RK@1236|Gammaproteobacteria,46DC8@72275|Alteromonadaceae 1236|Gammaproteobacteria P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec k141_33994_1 218284.CCDN010000001_gene1679 4.02e-90 268.0 COG1215@1|root,COG1215@2|Bacteria,1VUUB@1239|Firmicutes,4IS9M@91061|Bacilli,1ZCPM@1386|Bacillus 91061|Bacilli M Glycosyltransferase like family 2 tuaG GO:0003674,GO:0003824,GO:0016740,GO:0016757 - ko:K16698 - - - - ko00000,ko01000,ko01003 - GT2 iYO844.BSU35550 Glycos_transf_2 k141_16113_1 1453501.JELR01000002_gene1096 9.09e-223 616.0 COG1652@1|root,COG1652@2|Bacteria,1MUBV@1224|Proteobacteria,1RPMB@1236|Gammaproteobacteria,463ZS@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein containing LysM domain lysM - - - - - - - - - - - LysM k141_13957_1 1294265.JCM21738_415 2.22e-128 379.0 COG0243@1|root,COG0243@2|Bacteria,1TPZG@1239|Firmicutes,4HBA3@91061|Bacilli,1ZEAY@1386|Bacillus 91061|Bacilli C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - 1.8.5.3 ko:K07306 ko00920,map00920 - R09501 RC02555 ko00000,ko00001,ko01000,ko02000 5.A.3.3 - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal k141_23396_1 218284.CCDN010000006_gene3619 1.79e-98 298.0 COG1508@1|root,COG1508@2|Bacteria,1TQ0H@1239|Firmicutes,4HA8T@91061|Bacilli,1ZBKU@1386|Bacillus 91061|Bacilli K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog rpoN - - ko:K03092 ko02020,ko05111,map02020,map05111 - - - ko00000,ko00001,ko03021 - - - Sigma54_AID,Sigma54_CBD,Sigma54_DBD k141_6661_1 441769.ABFU01000056_gene874 3.66e-18 83.6 COG1488@1|root,COG1488@2|Bacteria,1TPDW@1239|Firmicutes,4HAI4@91061|Bacilli,1ZCGY@1386|Bacillus 91061|Bacilli H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP pncB - 6.3.4.21 ko:K00763 ko00760,ko01100,map00760,map01100 - R01724 RC00033 ko00000,ko00001,ko01000 - - iYO844.BSU31750 NAPRTase k141_6661_2 1294265.JCM21738_3117 9.51e-83 254.0 COG4191@1|root,COG4191@2|Bacteria,1TX8T@1239|Firmicutes,4I65R@91061|Bacilli,1ZEDP@1386|Bacillus 91061|Bacilli T GHKL domain - - - - - - - - - - - - HATPase_c,HisKA k141_24467_1 1294265.JCM21738_4574 1.36e-26 107.0 COG2812@1|root,COG2812@2|Bacteria,1TPS9@1239|Firmicutes,4HAUE@91061|Bacilli,1ZB2M@1386|Bacillus 91061|Bacilli L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity dnaX GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNA_pol3_gamma3 k141_17274_1 1385511.N783_19850 4.72e-75 238.0 COG1404@1|root,COG1404@2|Bacteria,1TQ2M@1239|Firmicutes,4HB7D@91061|Bacilli,2Y98N@289201|Pontibacillus 91061|Bacilli M Belongs to the peptidase S8 family - - 3.4.21.66 ko:K08651 - - - - ko00000,ko01000,ko01002,ko03110 - - - PPC,Peptidase_S8 k141_5571_1 426716.JOAJ01000009_gene5759 1.32e-122 375.0 2C593@1|root,2Z84R@2|Bacteria,2I0MZ@201174|Actinobacteria,4FVU9@85025|Nocardiaceae 201174|Actinobacteria - - - - - - - - - - - - - - - k141_4240_1 1307436.PBF_00905 8.75e-52 175.0 COG3039@1|root,COG3039@2|Bacteria,1TPFS@1239|Firmicutes,4H9V9@91061|Bacilli,1ZDIP@1386|Bacillus 91061|Bacilli L COG3666 Transposase and inactivated derivatives - - - - - - - - - - - - DDE_Tnp_1,DDE_Tnp_1_6,DUF772 k141_12767_1 218284.CCDN010000006_gene3768 2.86e-25 103.0 COG4191@1|root,COG4191@2|Bacteria,1TRYP@1239|Firmicutes,4HE85@91061|Bacilli,1ZBXM@1386|Bacillus 91061|Bacilli T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,HisK_N k141_12767_2 332101.JIBU02000020_gene2047 4.65e-23 99.8 COG1004@1|root,COG1004@2|Bacteria,1TQFN@1239|Firmicutes,25B1W@186801|Clostridia,36W7P@31979|Clostridiaceae 186801|Clostridia M Belongs to the UDP-glucose GDP-mannose dehydrogenase family ywqF - 1.1.1.22 ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 M00014,M00129,M00361,M00362 R00286 RC00291 ko00000,ko00001,ko00002,ko01000 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N k141_33995_1 268407.PWYN_15645 6.4e-94 285.0 COG1783@1|root,COG1783@2|Bacteria,1TRQP@1239|Firmicutes,4HDMY@91061|Bacilli,26WVX@186822|Paenibacillaceae 91061|Bacilli S Terminase RNAseH like domain - - - ko:K06909 - - - - ko00000 - - - Terminase_3,Terminase_3C k141_27856_1 1453501.JELR01000001_gene2863 8.49e-98 299.0 COG2072@1|root,COG2072@2|Bacteria,1MU71@1224|Proteobacteria,1RP8X@1236|Gammaproteobacteria,465CT@72275|Alteromonadaceae 1236|Gammaproteobacteria P flavoprotein involved in K transport ethA - - - - - - - - - - - FMO-like,NAD_binding_8,Pyr_redox_2,Pyr_redox_3 k141_1755_1 1169144.KB910938_gene1484 1.22e-05 45.8 COG1595@1|root,COG1595@2|Bacteria,1VEIP@1239|Firmicutes,4HJEM@91061|Bacilli,1ZQHV@1386|Bacillus 91061|Bacilli K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_31410_2 1116375.VEJY3_23826 1.14e-206 574.0 COG4606@1|root,COG4606@2|Bacteria,1MVSV@1224|Proteobacteria,1RQCK@1236|Gammaproteobacteria,1XTVI@135623|Vibrionales 135623|Vibrionales P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily - - - ko:K02015 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - FecCD k141_31410_3 1116375.VEJY3_23821 2.38e-186 521.0 COG4607@1|root,COG4607@2|Bacteria,1R54Y@1224|Proteobacteria,1RZ1I@1236|Gammaproteobacteria,1XURC@135623|Vibrionales 135623|Vibrionales P Periplasmic binding protein vctP - - ko:K02016 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - Peripla_BP_2 k141_31410_4 1116375.VEJY3_23816 2.19e-201 560.0 COG0583@1|root,COG0583@2|Bacteria,1N663@1224|Proteobacteria,1RMFD@1236|Gammaproteobacteria,1XVT1@135623|Vibrionales 135623|Vibrionales K Bacterial regulatory helix-turn-helix protein, lysR family - - - - - - - - - - - - HTH_1,LysR_substrate k141_31410_5 1116375.VEJY3_23811 0.0 1236.0 COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,1RNHR@1236|Gammaproteobacteria,1XV3F@135623|Vibrionales 135623|Vibrionales P Iron-regulated outer membrane virulence protein irgA GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - ko:K16089 - - - - ko00000,ko02000 1.B.14.1,1.B.14.10 - - Plug,TonB_dep_Rec k141_10347_1 218284.CCDN010000011_gene4410 5.49e-139 398.0 COG0805@1|root,COG0805@2|Bacteria,1U7N7@1239|Firmicutes,4HB1U@91061|Bacilli,1ZBYZ@1386|Bacillus 91061|Bacilli U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes tatC GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - ko:K03118 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - TatC k141_27100_1 42565.FP66_11300 5.59e-130 379.0 COG1181@1|root,COG1181@2|Bacteria,1R4RC@1224|Proteobacteria,1T297@1236|Gammaproteobacteria 1236|Gammaproteobacteria M ATP-grasp domain - - - - - - - - - - - - ATP-grasp_4,CPSase_L_D2 k141_6663_1 218284.CCDN010000001_gene1777 3.62e-20 80.9 2DR5F@1|root,33A90@2|Bacteria,1VK5I@1239|Firmicutes,4HRBW@91061|Bacilli,1ZK1Y@1386|Bacillus 91061|Bacilli S YvrJ protein family - - - - - - - - - - - - YvrJ k141_6663_2 218284.CCDN010000001_gene1778 2.44e-35 124.0 2C55I@1|root,32W42@2|Bacteria,1VD5J@1239|Firmicutes,4HMAT@91061|Bacilli,1ZGJA@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_29147_2 218284.CCDN010000005_gene3372 3.66e-108 317.0 COG0388@1|root,COG0388@2|Bacteria,1TQDK@1239|Firmicutes,4HC44@91061|Bacilli,1ZB5Z@1386|Bacillus 91061|Bacilli S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase mtnU - 3.5.1.3 ko:K13566 ko00250,map00250 - R00269,R00348 RC00010 ko00000,ko00001,ko01000 - - - CN_hydrolase k141_12768_1 218284.CCDN010000001_gene728 4.39e-142 409.0 COG0860@1|root,COG0860@2|Bacteria,1TSFS@1239|Firmicutes,4HACZ@91061|Bacilli,1ZAV0@1386|Bacillus 91061|Bacilli M stage II sporulation protein P spoIIP - - ko:K06385 - - - - ko00000 - - - SpoIIP k141_5573_1 218284.CCDN010000005_gene3356 8.67e-61 193.0 COG0861@1|root,COG0861@2|Bacteria,1TQ09@1239|Firmicutes,4HB99@91061|Bacilli,1ZBPQ@1386|Bacillus 91061|Bacilli P COG0861 Membrane protein TerC, possibly involved in tellurium resistance ykoY - - - - - - - - - - - TerC k141_1756_1 1295642.H839_04399 9.97e-102 304.0 COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,4HAEV@91061|Bacilli,1WETH@129337|Geobacillus 91061|Bacilli D Belongs to the SEDS family spoVE - - ko:K03588 ko04112,map04112 - - - ko00000,ko00001,ko02000,ko03036 2.A.103.1 - - FTSW_RODA_SPOVE k141_35230_2 1305836.AXVE01000006_gene318 9.82e-28 103.0 COG2210@1|root,COG2210@2|Bacteria,1VW6K@1239|Firmicutes,4HWNR@91061|Bacilli,26HE8@186818|Planococcaceae 91061|Bacilli S Belongs to the sulfur carrier protein TusA family - - - - - - - - - - - - - k141_814_1 1122194.AUHU01000009_gene3213 1.02e-133 410.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MV8W@1224|Proteobacteria,1RSN6@1236|Gammaproteobacteria,4662Q@72275|Alteromonadaceae 1236|Gammaproteobacteria P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec k141_11507_1 1042377.AFPJ01000055_gene957 8.03e-187 543.0 COG2366@1|root,COG2366@2|Bacteria,1MVMH@1224|Proteobacteria,1RMPX@1236|Gammaproteobacteria,464PP@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG2366 Protein related to penicillin acylase pvdQ - 3.5.1.97 ko:K07116 - - - - ko00000,ko01000 - - - Penicil_amidase k141_2972_1 1453501.JELR01000001_gene2448 4.93e-54 175.0 COG3047@1|root,COG3047@2|Bacteria 2|Bacteria - - ompW - - ko:K07275 - - - - ko00000 - - - OmpW k141_9070_1 218284.CCDN010000008_gene4046 3.18e-106 313.0 COG1396@1|root,COG1396@2|Bacteria,1V1KD@1239|Firmicutes,4HG1Q@91061|Bacilli,1ZEYC@1386|Bacillus 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_19,HTH_3,TPR_12,TPR_8 k141_33997_1 1217720.ALOX01000027_gene3664 7.35e-42 153.0 COG0492@1|root,COG0492@2|Bacteria,1MXI0@1224|Proteobacteria,2TUAR@28211|Alphaproteobacteria,2JRFF@204441|Rhodospirillales 204441|Rhodospirillales O L-lysine 6-monooxygenase (NADPH-requiring) - - - - - - - - - - - - Pyr_redox_3 k141_5574_1 1123261.AXDW01000007_gene2151 1.64e-89 267.0 COG0177@1|root,COG0177@2|Bacteria,1MUYQ@1224|Proteobacteria,1RMHU@1236|Gammaproteobacteria,1X340@135614|Xanthomonadales 135614|Xanthomonadales L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate nth - 4.2.99.18 ko:K10773 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD k141_25785_1 29581.BW37_04646 7.91e-11 63.2 COG0025@1|root,COG0025@2|Bacteria,1MW5T@1224|Proteobacteria,2VSFX@28216|Betaproteobacteria,478NM@75682|Oxalobacteraceae 28216|Betaproteobacteria P Sodium/hydrogen exchanger family - - - ko:K03316 - - - - ko00000 2.A.36 - - Na_H_Exchanger k141_25785_2 1042377.AFPJ01000005_gene2435 1.38e-298 825.0 COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,1RMVN@1236|Gammaproteobacteria,464V8@72275|Alteromonadaceae 1236|Gammaproteobacteria M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source glmS - 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 - R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 - - - GATase_6,SIS k141_7722_1 218284.CCDN010000001_gene991 3.19e-83 256.0 COG1703@1|root,COG1703@2|Bacteria,1TQT4@1239|Firmicutes,4H9ZJ@91061|Bacilli,1ZC78@1386|Bacillus 91061|Bacilli E periplasmic protein kinase ArgK and related GTPases of G3E family argK - - ko:K07588 - - - - ko00000,ko01000 - - - ArgK k141_20798_2 1042377.AFPJ01000044_gene643 0.0 1179.0 COG1680@1|root,COG1680@2|Bacteria,1MWHS@1224|Proteobacteria,1RRQF@1236|Gammaproteobacteria,46627@72275|Alteromonadaceae 1236|Gammaproteobacteria V COG1680 Beta-lactamase class C and other penicillin binding - - - - - - - - - - - - ASH,Beta-lactamase k141_17276_1 1089552.KI911559_gene2597 2.96e-20 99.0 COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,2TSGE@28211|Alphaproteobacteria,2JS1T@204441|Rhodospirillales 204441|Rhodospirillales S Sulfotransferase family - - - - - - - - - - - - Sulfotransfer_3,TPR_1,TPR_16,TPR_19,TPR_8 k141_35232_1 218284.CCDN010000004_gene3088 1.56e-121 362.0 COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,4HA1G@91061|Bacilli,1ZASC@1386|Bacillus 91061|Bacilli G COG0366 Glycosidases malL GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.2.1.10 ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00801,R01718,R01791,R06199 RC00028,RC00059,RC00077,RC00451 ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,Malt_amylase_C k141_32656_1 1295642.H839_05869 2.56e-51 171.0 COG1131@1|root,COG1131@2|Bacteria,1TPMQ@1239|Firmicutes,4HA8K@91061|Bacilli,1WG9T@129337|Geobacillus 91061|Bacilli V ATPases associated with a variety of cellular activities yfiL - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 k141_815_1 218284.CCDN010000001_gene449 1.21e-95 305.0 COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,4HAFP@91061|Bacilli,1ZBJ3@1386|Bacillus 91061|Bacilli V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran k141_11508_1 218284.CCDN010000001_gene1828 4.09e-81 255.0 COG0621@1|root,COG0621@2|Bacteria,1TNYN@1239|Firmicutes,4HAAS@91061|Bacilli,1ZBMF@1386|Bacillus 91061|Bacilli J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine miaB GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035597,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360 2.8.4.3 ko:K06168 - - R10645,R10646,R10647 RC00003,RC00980,RC03221,RC03222 ko00000,ko01000,ko03016 - - - Radical_SAM,TRAM,UPF0004 k141_11508_2 218284.CCDN010000001_gene1827 3.56e-70 213.0 COG4550@1|root,COG4550@2|Bacteria,1V4W0@1239|Firmicutes,4HH6Y@91061|Bacilli,1ZG72@1386|Bacillus 91061|Bacilli S Belongs to the UPF0342 family ymcA - 3.6.3.21 ko:K02028 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - Com_YlbF k141_13961_1 1294265.JCM21738_1913 1.41e-68 221.0 COG2340@1|root,COG2340@2|Bacteria,1V6GZ@1239|Firmicutes,4HJ21@91061|Bacilli,1ZDSK@1386|Bacillus 91061|Bacilli J protein with SCP PR1 domains - - - - - - - - - - - - CAP k141_13961_2 1294265.JCM21738_1914 2.53e-104 308.0 COG0564@1|root,COG0564@2|Bacteria,1TS1T@1239|Firmicutes,4HBRY@91061|Bacilli,1ZB25@1386|Bacillus 91061|Bacilli J Responsible for synthesis of pseudouridine from uracil rluD GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23,5.4.99.28,5.4.99.29 ko:K06177,ko:K06180 - - - - ko00000,ko01000,ko03009,ko03016 - - - PseudoU_synth_2 k141_37435_1 218284.CCDN010000005_gene3240 2.34e-273 759.0 COG0367@1|root,COG0367@2|Bacteria,1TRPB@1239|Firmicutes,4HA44@91061|Bacilli,1ZBY8@1386|Bacillus 91061|Bacilli E Asparagine synthase asnO - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 k141_37435_2 218284.CCDN010000005_gene3239 7.96e-22 89.4 2E4ZB@1|root,32ZT1@2|Bacteria,1VHAC@1239|Firmicutes,4HQBP@91061|Bacilli,1ZD5D@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2777) yisN - - - - - - - - - - - DUF2777 k141_31411_1 926549.KI421517_gene1847 3.07e-74 249.0 COG0532@1|root,COG0532@2|Bacteria,4NGP3@976|Bacteroidetes,47KGB@768503|Cytophagia 976|Bacteroidetes J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB - - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N k141_4405_4 1116375.VEJY3_01575 9.14e-142 424.0 COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,1RMH7@1236|Gammaproteobacteria,1XUHS@135623|Vibrionales 135623|Vibrionales S transport system, fused permease components - - - - - - - - - - - - DUF3394,DctM k141_36395_1 1453501.JELR01000002_gene1489 2.87e-118 365.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MUNK@1224|Proteobacteria,1RN9S@1236|Gammaproteobacteria,469NI@72275|Alteromonadaceae 1236|Gammaproteobacteria P receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_11784_3 218284.CCDN010000001_gene602 1.03e-66 210.0 COG0181@1|root,COG0181@2|Bacteria,1TPFQ@1239|Firmicutes,4H9TV@91061|Bacilli,1ZCR0@1386|Bacillus 91061|Bacilli H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps hemC GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00084 RC02317 ko00000,ko00001,ko00002,ko01000 - - - Porphobil_deam,Porphobil_deamC k141_7016_1 1294265.JCM21738_2405 2.32e-51 179.0 COG0668@1|root,COG0668@2|Bacteria,1TQXJ@1239|Firmicutes,4HCK2@91061|Bacilli,1ZF3F@1386|Bacillus 91061|Bacilli M Conserved TM helix ygxB - - - - - - - - - - - TM_helix k141_10469_1 1229205.BUPH_01124 3.71e-19 87.0 COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,2VKK5@28216|Betaproteobacteria,1KFE1@119060|Burkholderiaceae 28216|Betaproteobacteria C Pfam Iron-containing alcohol dehydrogenase - - 1.1.1.1 ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - Fe-ADH k141_10469_2 95619.PM1_0226890 3.11e-56 179.0 COG0824@1|root,COG0824@2|Bacteria,1RGZN@1224|Proteobacteria,1S64N@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Thioesterase - - - ko:K07107 - - - - ko00000,ko01000 - - - 4HBT,4HBT_2 k141_1051_1 985054.JQEZ01000003_gene1184 5.74e-25 105.0 COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2TTN3@28211|Alphaproteobacteria,4NBTZ@97050|Ruegeria 28211|Alphaproteobacteria P Binding-protein-dependent transport system inner membrane component oppB - - ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - BPD_transp_1 k141_23758_1 218284.CCDN010000001_gene512 6.91e-67 211.0 COG0825@1|root,COG0825@2|Bacteria,1UHNS@1239|Firmicutes,4HA4C@91061|Bacilli,1ZC5V@1386|Bacillus 91061|Bacilli I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA accA - 2.1.3.15,6.4.1.2 ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - ACCA k141_30390_1 1279017.AQYJ01000029_gene3403 1.92e-61 202.0 COG4235@1|root,COG4235@2|Bacteria,1MY4J@1224|Proteobacteria,1S358@1236|Gammaproteobacteria,466S6@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG4235 Cytochrome c biogenesis factor cycH - - ko:K02200 - - - - ko00000 - - - TPR_16,TPR_2 k141_1944_1 1403819.BATR01000004_gene112 1.19e-26 102.0 COG3011@1|root,COG3011@2|Bacteria,46WSM@74201|Verrucomicrobia,2IUZ8@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Protein of unknown function, DUF393 - - - - - - - - - - - - DUF393 k141_22422_1 1221522.B723_11425 4.2e-194 543.0 COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,1RMBM@1236|Gammaproteobacteria,1YNNP@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria G Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain gap - 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N k141_1052_1 218284.CCDN010000002_gene2157 2.1e-113 334.0 COG1609@1|root,COG1609@2|Bacteria,1TRFH@1239|Firmicutes,4HE9A@91061|Bacilli,1ZQ1D@1386|Bacillus 91061|Bacilli K helix_turn _helix lactose operon repressor - - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 k141_28028_1 649639.Bcell_1181 1.27e-77 250.0 COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,4HCEP@91061|Bacilli,1ZBU0@1386|Bacillus 91061|Bacilli C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family - - - - - - - - - - - - Oxidored_FMN,Pyr_redox_2 k141_7017_1 1453501.JELR01000001_gene2409 4.05e-93 282.0 COG3203@1|root,COG3203@2|Bacteria,1MWUN@1224|Proteobacteria,1RZ26@1236|Gammaproteobacteria,466WT@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG3203 Outer membrane protein (porin) ifcO - - - - - - - - - - - Porin_4 k141_31542_1 379066.GAU_0146 9.39e-44 162.0 COG5276@1|root,COG5492@1|root,COG5276@2|Bacteria,COG5492@2|Bacteria,1ZU8T@142182|Gemmatimonadetes 142182|Gemmatimonadetes N LVIVD repeat - - - - - - - - - - - - LVIVD k141_15101_1 1453501.JELR01000002_gene1139 2.25e-80 248.0 COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,1RREX@1236|Gammaproteobacteria,4666W@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit pdhA - 1.2.4.1 ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh k141_15101_2 1042377.AFPJ01000005_gene2432 6.2e-07 50.4 COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,1RP3G@1236|Gammaproteobacteria,465NK@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit pdhB - 1.2.4.1 ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C k141_10471_1 218284.CCDN010000001_gene963 1.25e-86 255.0 COG1302@1|root,COG1302@2|Bacteria,1V4IC@1239|Firmicutes,4HJ7T@91061|Bacilli,1ZG6N@1386|Bacillus 91061|Bacilli S protein conserved in bacteria yqhY - - - - - - - - - - - Asp23 k141_30391_1 218284.CCDN010000001_gene1341 1.35e-106 328.0 COG4548@1|root,COG4548@2|Bacteria,1TPW1@1239|Firmicutes,4HCPJ@91061|Bacilli,1ZD6R@1386|Bacillus 91061|Bacilli P Von Willebrand factor yojO - - - - - - - - - - - CobT_C,VWA k141_4406_1 1254432.SCE1572_35290 1.97e-125 364.0 COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,43AB6@68525|delta/epsilon subdivisions,2X259@28221|Deltaproteobacteria,2YZEP@29|Myxococcales 28221|Deltaproteobacteria I Belongs to the enoyl-CoA hydratase isomerase family - - - - - - - - - - - - ECH_1 k141_4406_2 1123501.KB902279_gene597 1.92e-06 49.7 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria 28211|Alphaproteobacteria C belongs to the aldehyde dehydrogenase family gabD - 1.2.1.16,1.2.1.20,1.2.1.79 ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 M00027 R00713,R00714,R02401 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_1053_1 1279017.AQYJ01000027_gene1981 1.54e-205 593.0 COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,1RPFM@1236|Gammaproteobacteria,4673P@72275|Alteromonadaceae 1236|Gammaproteobacteria M protein involved in outer membrane biogenesis asmA - - ko:K07289 - - - - ko00000 - - - AsmA k141_1947_1 218284.CCDN010000004_gene3056 2.22e-32 117.0 2DKHE@1|root,309GB@2|Bacteria,1U50R@1239|Firmicutes,4IESM@91061|Bacilli,1ZI04@1386|Bacillus 91061|Bacilli S Intracellular proteinase inhibitor - - - - - - - - - - - - BsuPI k141_1947_2 218284.CCDN010000004_gene3055 9.18e-14 70.5 COG4134@1|root,COG4134@2|Bacteria,1TR3G@1239|Firmicutes,4HAW1@91061|Bacilli,1ZD00@1386|Bacillus 91061|Bacilli S Bacterial extracellular solute-binding protein - - - ko:K02055 ko02024,map02024 M00193 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11 - - SBP_bac_8 k141_24735_2 1042377.AFPJ01000043_gene954 1.01e-221 623.0 COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,1RMWU@1236|Gammaproteobacteria,4658B@72275|Alteromonadaceae 1236|Gammaproteobacteria M Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation surA GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006457,GO:0006458,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0022607,GO:0030288,GO:0030313,GO:0031647,GO:0031975,GO:0033218,GO:0036211,GO:0042277,GO:0042597,GO:0043163,GO:0043165,GO:0043170,GO:0043412,GO:0044085,GO:0044091,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0044764,GO:0045229,GO:0050821,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0060274,GO:0061024,GO:0061077,GO:0065007,GO:0065008,GO:0071704,GO:0071709,GO:0071840,GO:0140096,GO:1901564 5.2.1.8 ko:K03771 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_3,SurA_N k141_24735_3 1042377.AFPJ01000043_gene953 4.3e-19 87.4 COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,1RNZV@1236|Gammaproteobacteria,464RG@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) pdxA GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008614,GO:0008615,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0036094,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046184,GO:0046483,GO:0046872,GO:0046914,GO:0048037,GO:0050570,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.1.1.262 ko:K00097 ko00750,ko01100,map00750,map01100 M00124 R05681,R05837,R07406 RC00089,RC00675,RC01475 ko00000,ko00001,ko00002,ko01000 - - iECO111_1330.ECO111_0056 PdxA k141_26043_1 1042377.AFPJ01000043_gene955 4.03e-284 800.0 COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,1RQEX@1236|Gammaproteobacteria,463Z7@72275|Alteromonadaceae 1236|Gammaproteobacteria M Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane lptD GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0009279,GO:0009636,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0042221,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0050896,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:1901264 - ko:K04744 - - - - ko00000,ko02000 1.B.42.1 - iG2583_1286.G2583_0058 OstA,OstA_C k141_26043_3 1042377.AFPJ01000043_gene953 2.38e-172 488.0 COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,1RNZV@1236|Gammaproteobacteria,464RG@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) pdxA GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008614,GO:0008615,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0036094,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046184,GO:0046483,GO:0046872,GO:0046914,GO:0048037,GO:0050570,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.1.1.262 ko:K00097 ko00750,ko01100,map00750,map01100 M00124 R05681,R05837,R07406 RC00089,RC00675,RC01475 ko00000,ko00001,ko00002,ko01000 - - iECO111_1330.ECO111_0056 PdxA k141_16335_1 1042377.AFPJ01000053_gene1518 1.37e-241 669.0 COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,1RP0C@1236|Gammaproteobacteria,465BZ@72275|Alteromonadaceae 1236|Gammaproteobacteria H Aminotransferase class-III - - 2.6.1.18 ko:K00822 ko00280,ko00410,ko00640,ko01100,map00280,map00410,map00640,map01100 - R00907,R04187 RC00008,RC00062,RC00160 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_3 k141_20994_2 1279017.AQYJ01000028_gene2281 4.86e-10 59.3 COG2211@1|root,COG2211@2|Bacteria,1MX4Z@1224|Proteobacteria,1RRNW@1236|Gammaproteobacteria,464IV@72275|Alteromonadaceae 1236|Gammaproteobacteria G COG0477 Permeases of the major facilitator superfamily - - - ko:K16211 - - - - ko00000,ko02000 2.A.2.6 - - MFS_1,MFS_2 k141_28057_1 1121091.AUMP01000008_gene3567 1.67e-71 241.0 COG0737@1|root,COG0737@2|Bacteria,1TPV2@1239|Firmicutes,4HB9S@91061|Bacilli 91061|Bacilli F Belongs to the 5'-nucleotidase family - - 3.1.3.5,3.1.3.6,3.1.4.16 ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01562,R01569,R01664,R01877,R01968,R02088,R02102,R02148,R02370,R02719,R03537,R03538,R03929,R05135 RC00017,RC00078,RC00296 ko00000,ko00001,ko01000 - - - 5_nucleotid_C,Metallophos k141_7063_1 1279017.AQYJ01000027_gene1683 6.57e-153 463.0 COG5013@1|root,COG5013@2|Bacteria,1MW9S@1224|Proteobacteria,1RQ27@1236|Gammaproteobacteria,465D5@72275|Alteromonadaceae 1236|Gammaproteobacteria C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family narG GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009898,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0031235,GO:0032991,GO:0042126,GO:0043436,GO:0043546,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0097159,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098803,GO:1901363,GO:1902494,GO:1990204,GO:2001057 1.7.5.1 ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 M00529,M00530,M00804 R00798,R01106,R09497 RC02812 ko00000,ko00001,ko00002,ko01000 5.A.3.1 - iSBO_1134.SBO_1842,iUMN146_1321.UM146_09685 Molybdopterin,Molydop_binding,Nitr_red_alph_N k141_22447_2 398720.MED217_10522 3.64e-08 60.5 COG4772@1|root,COG4772@2|Bacteria,4NH5V@976|Bacteroidetes,1HZ6R@117743|Flavobacteriia,2XJNR@283735|Leeuwenhoekiella 976|Bacteroidetes P TonB dependent receptor fecA - - ko:K16091 - - - - ko00000,ko02000 1.B.14.1.14 - - CarbopepD_reg_2,Plug,TonB_dep_Rec k141_16362_1 1116375.VEJY3_06485 1.47e-135 392.0 COG2195@1|root,COG2195@2|Bacteria,1MV7D@1224|Proteobacteria,1TH92@1236|Gammaproteobacteria,1XSN9@135623|Vibrionales 135623|Vibrionales E COG2195 Di- and tripeptidases - - 3.4.11.4 ko:K01258 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20,Peptidase_M28 k141_3243_2 1453501.JELR01000001_gene3147 1.83e-205 580.0 COG0577@1|root,COG0577@2|Bacteria,1QSVW@1224|Proteobacteria,1RPBM@1236|Gammaproteobacteria,465M6@72275|Alteromonadaceae 1236|Gammaproteobacteria V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD k141_32954_1 1033734.CAET01000048_gene1669 2.02e-64 204.0 COG1175@1|root,COG1175@2|Bacteria,1TP1Q@1239|Firmicutes,4HCFJ@91061|Bacilli,1ZDIC@1386|Bacillus 91061|Bacilli G Binding-protein-dependent transport system inner membrane component - - - ko:K10118 ko02010,map02010 M00196 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.28 - - BPD_transp_1 k141_32954_2 86416.Clopa_3948 6.63e-08 53.9 COG0395@1|root,COG0395@2|Bacteria,1TR45@1239|Firmicutes,24A48@186801|Clostridia,36EZR@31979|Clostridiaceae 186801|Clostridia P PFAM Binding-protein-dependent transport system inner membrane component - - - ko:K10119 ko02010,map02010 M00196 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.28 - - BPD_transp_1 k141_35527_1 1042377.AFPJ01000052_gene1566 3.62e-164 464.0 COG3220@1|root,COG3220@2|Bacteria,1MURE@1224|Proteobacteria,1RQ9H@1236|Gammaproteobacteria,464IP@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria - - - ko:K09930 - - - - ko00000 - - - DUF692 k141_35527_2 1415778.JQMM01000001_gene1829 2.15e-39 139.0 COG3219@1|root,COG3219@2|Bacteria,1R8C9@1224|Proteobacteria,1S23S@1236|Gammaproteobacteria,1J6PK@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria - - - ko:K09929 - - - - ko00000 - - - DUF2063 k141_30408_1 42565.FP66_07560 5.39e-129 376.0 COG0317@1|root,COG0460@1|root,COG0317@2|Bacteria,COG0460@2|Bacteria,1MUDC@1224|Proteobacteria,1RPEU@1236|Gammaproteobacteria,1XHWG@135619|Oceanospirillales 135619|Oceanospirillales E homoserine dehydrogenase hom - 1.1.1.3 ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00017,M00018 R01773,R01775 RC00087 ko00000,ko00001,ko00002,ko01000 - - - ACT,Homoserine_dh,NAD_binding_3 k141_30408_2 42565.FP66_07565 3.66e-49 162.0 COG1651@1|root,COG1651@2|Bacteria,1RD39@1224|Proteobacteria,1S3U8@1236|Gammaproteobacteria,1XJNT@135619|Oceanospirillales 135619|Oceanospirillales O Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - 5.3.4.1 ko:K03981 - - - - ko00000,ko01000,ko02044,ko03110 3.A.7.11.1 - - DsbC_N,Thioredoxin_2 k141_20029_1 1279017.AQYJ01000027_gene1855 2.6e-150 456.0 COG0308@1|root,COG0308@2|Bacteria,1PTWJ@1224|Proteobacteria,1RZH5@1236|Gammaproteobacteria,465WC@72275|Alteromonadaceae 1236|Gammaproteobacteria E Peptidase family M1 domain - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_2,ABC2_membrane_4,Peptidase_M1 k141_4421_1 440512.C211_14281 3.72e-22 105.0 COG2199@1|root,COG3706@2|Bacteria,1R51K@1224|Proteobacteria,1SYWV@1236|Gammaproteobacteria 1236|Gammaproteobacteria T COG2202 FOG PAS PAC domain - - - - - - - - - - - - GGDEF,PAS_9 k141_4421_3 466088.CL42_09940 2.07e-21 101.0 COG2207@1|root,COG2207@2|Bacteria,1RH01@1224|Proteobacteria,1SBYD@1236|Gammaproteobacteria,3NKC6@468|Moraxellaceae 1236|Gammaproteobacteria K Arabinose-binding domain of AraC transcription regulator, N-term - - - - - - - - - - - - Arabinose_bd,HTH_18 k141_4421_4 339670.Bamb_6095 1.25e-201 570.0 COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2W8AG@28216|Betaproteobacteria,1K3RU@119060|Burkholderiaceae 28216|Betaproteobacteria H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - - - - - - - - - - Aminotran_3 k141_29435_1 452637.Oter_0831 3.13e-38 144.0 COG2366@1|root,COG2366@2|Bacteria 2|Bacteria D antibiotic biosynthetic process acyII - 3.5.1.11 ko:K01434 ko00311,ko01130,map00311,map01130 - R02170 RC00166,RC00328 ko00000,ko00001,ko01000,ko01002 - - - Penicil_amidase k141_29435_2 1123501.KB902281_gene338 6.2e-31 116.0 COG0714@1|root,COG0714@2|Bacteria,1MV5I@1224|Proteobacteria,2TRI8@28211|Alphaproteobacteria 28211|Alphaproteobacteria S ATPase (AAA) MA20_01295 - - - - - - - - - - - AAA,AAA_5 k141_12971_1 42565.FP66_03980 4.94e-102 328.0 COG2902@1|root,COG2902@2|Bacteria,1MXNV@1224|Proteobacteria,1RQVZ@1236|Gammaproteobacteria,1XI6H@135619|Oceanospirillales 135619|Oceanospirillales E Dehydrogenase - - 1.4.1.2 ko:K15371 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 - R00243 RC00006,RC02799 ko00000,ko00001,ko01000 - - - Bac_GDH k141_28058_1 1294265.JCM21738_4476 1.7e-80 249.0 COG0768@1|root,COG0768@2|Bacteria,1TQKI@1239|Firmicutes,4HC5S@91061|Bacilli,1ZBDB@1386|Bacillus 91061|Bacilli M Penicillin-binding Protein pbpI - - ko:K21468 - - - - ko00000,ko01011 - - - PBP_dimer,Transpeptidase k141_28058_2 1294265.JCM21738_4477 2.91e-25 99.8 2BJ57@1|root,32DEE@2|Bacteria,1V93H@1239|Firmicutes,4HN71@91061|Bacilli,1ZH00@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF1510) yrrS - - - - - - - - - - - DUF1510 k141_1974_2 997296.PB1_13944 6.15e-64 204.0 28RMR@1|root,2ZE0H@2|Bacteria,1V1HS@1239|Firmicutes,4HFRG@91061|Bacilli,1ZANV@1386|Bacillus 91061|Bacilli S sporulation protein ypjB - - - - - - - - - - - Spore_YpjB k141_32955_2 935836.JAEL01000071_gene4033 3.69e-15 75.5 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HA2A@91061|Bacilli,1ZBG3@1386|Bacillus 91061|Bacilli I acyl-CoA dehydrogenase mmgC - - ko:K18244 - - - - ko00000,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_3244_1 1453501.JELR01000002_gene112 2.25e-105 308.0 COG4544@1|root,COG4544@2|Bacteria,1MZQU@1224|Proteobacteria,1S9RP@1236|Gammaproteobacteria,467W8@72275|Alteromonadaceae 1236|Gammaproteobacteria S Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division - - - ko:K13053,ko:K14160 - - - - ko00000,ko03036,ko03400 - - - RecA,SulA k141_31566_1 218284.CCDN010000001_gene17 4.15e-73 223.0 COG0806@1|root,COG0806@2|Bacteria,1V6HD@1239|Firmicutes,4HH3H@91061|Bacilli,1ZFP2@1386|Bacillus 91061|Bacilli J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes rimM - - ko:K02860 - - - - ko00000,ko03009 - - - PRC,RimM k141_20031_1 1294265.JCM21738_4105 8.12e-98 289.0 COG0543@1|root,COG0543@2|Bacteria,1TQ5D@1239|Firmicutes,4HAU4@91061|Bacilli,1ZBJI@1386|Bacillus 91061|Bacilli C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) pyrK GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042602,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0052875,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - ko:K02823 ko00240,ko01100,map00240,map01100 - - - ko00000,ko00001 - - iYO844.BSU15530 DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1 k141_22449_1 1279017.AQYJ01000023_gene3160 6.51e-144 424.0 COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,1RPJB@1236|Gammaproteobacteria,466BN@72275|Alteromonadaceae 1236|Gammaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoN GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 ko:K00343 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_M k141_29436_1 42565.FP66_11315 7.97e-48 161.0 2E2S0@1|root,32XUC@2|Bacteria,1N3J9@1224|Proteobacteria,1SEDM@1236|Gammaproteobacteria,1XQAY@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_29436_2 42565.FP66_11310 2.25e-16 77.8 COG3853@1|root,COG3853@2|Bacteria,1MY18@1224|Proteobacteria,1RZ1H@1236|Gammaproteobacteria,1XMQ5@135619|Oceanospirillales 135619|Oceanospirillales P Toxic anion resistance - - - - - - - - - - - - TelA k141_26072_1 1116375.VEJY3_01960 3.18e-150 433.0 COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,1XSK2@135623|Vibrionales 135623|Vibrionales M Belongs to the peptidase S1C family degQ - 3.4.21.107 ko:K04771,ko:K04772 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ,PDZ_2,Trypsin_2 k141_1077_1 1219076.N646_1069 2.41e-82 246.0 COG1335@1|root,COG1335@2|Bacteria,1MU5N@1224|Proteobacteria,1S7F3@1236|Gammaproteobacteria,1XWWK@135623|Vibrionales 135623|Vibrionales Q Isochorismatase family - - - - - - - - - - - - Isochorismatase k141_1077_2 1219076.N646_1068 1.64e-192 537.0 COG2515@1|root,COG2515@2|Bacteria,1R87T@1224|Proteobacteria,1RRB2@1236|Gammaproteobacteria,1XU3I@135623|Vibrionales 135623|Vibrionales E COG2515 1-aminocyclopropane-1-carboxylate deaminase - - - - - - - - - - - - PALP k141_1077_3 1116375.VEJY3_10370 1.05e-252 699.0 COG0642@1|root,COG0642@2|Bacteria,1R9P9@1224|Proteobacteria,1S0KV@1236|Gammaproteobacteria,1XSGZ@135623|Vibrionales 135623|Vibrionales T COG0642 Signal transduction histidine kinase - - - - - - - - - - - - HATPase_c,HisKA k141_1077_4 1116375.VEJY3_10365 2.12e-151 426.0 COG0745@1|root,COG0745@2|Bacteria,1RA00@1224|Proteobacteria,1S23N@1236|Gammaproteobacteria,1XUTV@135623|Vibrionales 135623|Vibrionales K COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - - - - - - - - - - Response_reg,Trans_reg_C k141_1077_5 1116375.VEJY3_10360 0.0 1454.0 COG1032@1|root,COG1032@2|Bacteria,1MUG3@1224|Proteobacteria,1RN9V@1236|Gammaproteobacteria,1XT35@135623|Vibrionales 135623|Vibrionales C UPF0313 protein ygiQ - - - - - - - - - - - DUF3362,Radical_SAM,Radical_SAM_N k141_1077_6 223926.28806970 6.89e-138 392.0 2E04S@1|root,32VT8@2|Bacteria,1N3T4@1224|Proteobacteria,1SBN3@1236|Gammaproteobacteria,1XTHM@135623|Vibrionales 135623|Vibrionales - - VV2139 - - - - - - - - - - - - k141_1077_7 1116375.VEJY3_10345 4.58e-38 127.0 2EG1V@1|root,339TV@2|Bacteria,1NI0B@1224|Proteobacteria,1SGIA@1236|Gammaproteobacteria,1XYCW@135623|Vibrionales 135623|Vibrionales S Domain of unknown function (DUF4250) VC1707 - - - - - - - - - - - DUF4250 k141_1077_8 223926.28806968 1.3e-209 580.0 COG0583@1|root,COG0583@2|Bacteria,1MUIX@1224|Proteobacteria,1RRF3@1236|Gammaproteobacteria,1XTEB@135623|Vibrionales 135623|Vibrionales K COG0583 Transcriptional regulator metR - - ko:K03576 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate k141_1077_9 223926.28806966 0.0 1333.0 COG0620@1|root,COG0620@2|Bacteria,1MUI9@1224|Proteobacteria,1RMBA@1236|Gammaproteobacteria,1XSM3@135623|Vibrionales 135623|Vibrionales E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation metE GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0042085,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050667,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_1,Meth_synt_2 k141_5793_1 1395571.TMS3_0115425 9.31e-72 236.0 COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,1RR5Z@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Allophanate hydrolase atzF - 3.5.1.54 ko:K01457 ko00220,ko00791,ko01100,ko01120,map00220,map00791,map01100,map01120 - R00005 RC02756 ko00000,ko00001,ko01000 - - - Amidase k141_5793_2 1238450.VIBNISOn1_1390026 4.78e-100 300.0 COG0510@1|root,COG0510@2|Bacteria,1RC6V@1224|Proteobacteria,1S2J9@1236|Gammaproteobacteria,1XWN2@135623|Vibrionales 135623|Vibrionales M thiamine kinase activity - - - - - - - - - - - - APH k141_32956_1 218284.CCDN010000001_gene200 3.38e-148 431.0 COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,4H9VD@91061|Bacilli,1ZAU2@1386|Bacillus 91061|Bacilli G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) ptsI GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0051179,GO:0051234,GO:0071702 2.7.3.9 ko:K08483 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 8.A.7 - - PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C k141_11831_1 218284.CCDN010000001_gene1064 8.58e-109 329.0 COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HBZ0@91061|Bacilli,1ZAQC@1386|Bacillus 91061|Bacilli T Histidine kinase resE - 2.7.13.3 ko:K07651 ko02020,map02020 M00458 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,PAS,PAS_4 k141_4423_1 1453501.JELR01000002_gene1144 6.54e-21 94.7 COG2304@1|root,COG2931@1|root,COG3210@1|root,COG2304@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,1R1GH@1224|Proteobacteria,1T525@1236|Gammaproteobacteria 1236|Gammaproteobacteria U oxidoreductase activity - - - - - - - - - - - - - k141_4423_2 1121935.AQXX01000135_gene3758 2.43e-07 51.6 COG1335@1|root,COG1335@2|Bacteria,1RE3C@1224|Proteobacteria,1S9BD@1236|Gammaproteobacteria,1XPI2@135619|Oceanospirillales 135619|Oceanospirillales Q Isochorismatase family - - - - - - - - - - - - Isochorismatase k141_1975_1 218284.CCDN010000002_gene2169 4.35e-37 127.0 2B02J@1|root,31SCS@2|Bacteria,1V9YF@1239|Firmicutes,4HKUD@91061|Bacilli,1ZHUD@1386|Bacillus 91061|Bacilli - - liaI - - ko:K11619 ko02020,map02020 M00754 - - ko00000,ko00001,ko00002 - - - - k141_7064_1 55601.VANGNB10_cI0962c 8.06e-24 93.2 COG4628@1|root,COG4628@2|Bacteria,1N7DG@1224|Proteobacteria,1S2VZ@1236|Gammaproteobacteria,1XX0U@135623|Vibrionales 135623|Vibrionales S DNA-binding protein VF530 - - - - - - - - - - - - VF530 k141_7064_2 1238182.C882_1585 1.85e-62 217.0 COG3420@1|root,COG3420@2|Bacteria,1R629@1224|Proteobacteria,2URG7@28211|Alphaproteobacteria 28211|Alphaproteobacteria P alginic acid biosynthetic process - - - - - - - - - - - - - k141_5794_1 1453501.JELR01000002_gene129 7.52e-23 99.8 COG3203@1|root,COG3203@2|Bacteria,1MX4Q@1224|Proteobacteria,1RY5B@1236|Gammaproteobacteria,4654M@72275|Alteromonadaceae 1236|Gammaproteobacteria M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - - - - - - - - - - Porin_2 k141_28060_1 314262.MED193_07708 1.04e-09 65.5 COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2TQND@28211|Alphaproteobacteria,2P4C2@2433|Roseobacter 28211|Alphaproteobacteria H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family bioA - 2.6.1.62 ko:K00833 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R03231 RC00006,RC00887 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 k141_1078_1 1385511.N783_11330 1.16e-06 49.7 28NEN@1|root,2ZBH5@2|Bacteria,1VH0Z@1239|Firmicutes,4HWEC@91061|Bacilli,2YBG4@289201|Pontibacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_1078_2 1385514.N782_16445 6.58e-24 104.0 COG0642@1|root,COG2205@2|Bacteria,1U59C@1239|Firmicutes,4ITWI@91061|Bacilli,2YBGG@289201|Pontibacillus 91061|Bacilli T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA k141_3245_1 574375.BAGA_06545 3.34e-106 342.0 COG1404@1|root,COG1404@2|Bacteria,1TPH1@1239|Firmicutes,4HBQH@91061|Bacilli,1ZBS0@1386|Bacillus 91061|Bacilli O Belongs to the peptidase S8 family prtS - 3.4.21.110,3.4.21.96 ko:K01361,ko:K08652 - - - - ko00000,ko01000,ko01002,ko03110 - - - FIVAR,Gram_pos_anchor,Inhibitor_I9,PA,Peptidase_S8,SLH,YSIRK_signal,fn3_5 k141_29438_1 1046625.AFQY01000003_gene2342 4.66e-12 66.6 COG2207@1|root,COG2207@2|Bacteria,1RG3C@1224|Proteobacteria,1S50G@1236|Gammaproteobacteria,3NT3F@468|Moraxellaceae 1236|Gammaproteobacteria K Arabinose-binding domain of AraC transcription regulator, N-term - - - - - - - - - - - - Arabinose_bd,HTH_18 k141_29438_2 1042377.AFPJ01000020_gene2059 1.6e-32 127.0 COG0457@1|root,COG0457@2|Bacteria,1MX2U@1224|Proteobacteria,1RPD2@1236|Gammaproteobacteria,464NG@72275|Alteromonadaceae 1236|Gammaproteobacteria C Cytochrome c554 and c-prime - - - - - - - - - - - - Cytochrome_C554,HEAT_2,Paired_CXXCH_1,TPR_16,TPR_19,TPR_20,TPR_8 k141_12973_1 1156919.QWC_12538 4.05e-41 153.0 COG3170@1|root,COG3170@2|Bacteria,1N4R0@1224|Proteobacteria,2VPR6@28216|Betaproteobacteria 28216|Betaproteobacteria NU Tfp pilus assembly protein FimV - - - - - - - - - - - - P22_portal k141_1976_1 218284.CCDN010000001_gene1697 7.14e-14 70.1 COG1633@1|root,COG4902@1|root,COG1633@2|Bacteria,COG4902@2|Bacteria,1V9AF@1239|Firmicutes,4HIP7@91061|Bacilli,1ZGFE@1386|Bacillus 91061|Bacilli S Rubrerythrin yhjR - - - - - - - - - - - DUF2202,Ferritin_2,Rubrerythrin k141_23797_2 223926.28807151 4.23e-190 530.0 COG0676@1|root,COG0676@2|Bacteria,1Q7VN@1224|Proteobacteria,1RQK0@1236|Gammaproteobacteria,1XSYW@135623|Vibrionales 135623|Vibrionales G Belongs to the glucose-6-phosphate 1-epimerase family - - 5.1.3.15 ko:K01792 ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130 - R02739 RC00563 ko00000,ko00001,ko01000 - - - Aldose_epim k141_23797_3 1219076.N646_1264 2.52e-237 652.0 COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,1RMBM@1236|Gammaproteobacteria,1XTWD@135623|Vibrionales 135623|Vibrionales C Belongs to the glyceraldehyde-3-phosphate dehydrogenase family gapA - 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N k141_23797_4 1116375.VEJY3_11150 1.92e-90 266.0 COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,1S5WI@1236|Gammaproteobacteria,1XXFA@135623|Vibrionales 135623|Vibrionales C Belongs to the MsrB Met sulfoxide reductase family msrB - 1.8.4.12 ko:K07305 - - - - ko00000,ko01000 - - - SelR k141_23797_5 1116375.VEJY3_11145 1.82e-146 418.0 2CF8J@1|root,2Z7JD@2|Bacteria,1MYC8@1224|Proteobacteria,1RPF0@1236|Gammaproteobacteria,1XTQQ@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF2989) VC1997 - - - - - - - - - - - DUF2989 k141_23797_6 674977.VMC_15180 2.33e-58 181.0 COG3139@1|root,COG3139@2|Bacteria,1N6T3@1224|Proteobacteria,1SCFV@1236|Gammaproteobacteria,1XXXK@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria - - - ko:K09916 - - - - ko00000 - - - DUF1315 k141_28556_2 1453501.JELR01000002_gene623 1.12e-44 152.0 COG0463@1|root,COG0463@2|Bacteria,1MX1N@1224|Proteobacteria,1S06M@1236|Gammaproteobacteria,464R2@72275|Alteromonadaceae 1236|Gammaproteobacteria M Glycosyl transferase, family 2 - - - - - - - - - - - - Glycos_transf_2 k141_2398_1 1294265.JCM21738_1247 1.49e-103 307.0 COG1541@1|root,COG1541@2|Bacteria,1TQA1@1239|Firmicutes,4HAU0@91061|Bacilli,1ZBRF@1386|Bacillus 91061|Bacilli H Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) paaK - 6.2.1.30 ko:K01912 ko00360,ko01120,ko05111,map00360,map01120,map05111 - R02539 RC00004,RC00014 ko00000,ko00001,ko01000 - - - AMP-binding,AMP-binding_C_2 k141_15479_2 665959.HMPREF1013_04393 9.24e-36 124.0 2E921@1|root,333B6@2|Bacteria,1VEYW@1239|Firmicutes,4HP1A@91061|Bacilli,1ZI2V@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_26175_1 1294265.JCM21738_3028 1.85e-48 163.0 COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,4H9SZ@91061|Bacilli,1ZAX7@1386|Bacillus 91061|Bacilli E Sodium alanine symporter glnT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03310,ko:K11626 ko02020,map02020 - - - ko00000,ko00001 2.A.25 - - Na_Ala_symp k141_4782_2 1405498.SSIM_04825 4.53e-07 52.8 2E6FV@1|root,33136@2|Bacteria,1VH2N@1239|Firmicutes,4HQRC@91061|Bacilli,4GZUA@90964|Staphylococcaceae 91061|Bacilli S Phage tail assembly chaperone protein, TAC - - - - - - - - - - - - Phage_TAC_12 k141_20219_1 1321781.HMPREF1985_00665 2.37e-42 162.0 COG3866@1|root,COG3866@2|Bacteria,1U9EG@1239|Firmicutes,4H3NR@909932|Negativicutes 909932|Negativicutes G Pectate lyase pel - 4.2.2.2 ko:K01728 ko00040,ko02024,map00040,map02024 - R02361,R06240 RC00049,RC00705 ko00000,ko00001,ko01000 - - - Pec_lyase_C k141_20219_2 1348635.BBJY01000003_gene3780 0.0 1044.0 COG2755@1|root,COG2755@2|Bacteria,1QW27@1224|Proteobacteria,1T2Q7@1236|Gammaproteobacteria,1Y3CJ@135623|Vibrionales 135623|Vibrionales E lipolytic protein G-D-S-L family - - - - - - - - - - - - - k141_20219_3 1348635.BBJY01000003_gene3779 1.65e-75 235.0 COG1452@1|root,COG1452@2|Bacteria,1PKU7@1224|Proteobacteria,1S2IR@1236|Gammaproteobacteria,1XX2I@135623|Vibrionales 135623|Vibrionales M Oligogalacturonate-specific porin protein (KdgM) - - - ko:K22110 - - - - ko00000,ko02000 1.B.35.1,1.B.35.2 - - KdgM k141_20219_4 1348635.BBJY01000003_gene3778 4.75e-135 387.0 COG1175@1|root,COG1175@2|Bacteria,1MVAP@1224|Proteobacteria,1RYI1@1236|Gammaproteobacteria,1Y25Z@135623|Vibrionales 135623|Vibrionales G Binding-protein-dependent transport system inner membrane component - - - - - - - - - - - - BPD_transp_1 k141_21426_2 1331060.RLDS_25825 6.26e-28 103.0 2DJKR@1|root,32YT5@2|Bacteria,1NACC@1224|Proteobacteria,2UIBJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_8350_1 880073.Calab_0834 1.8e-24 108.0 COG3385@1|root,COG3385@2|Bacteria,2NRDU@2323|unclassified Bacteria 2|Bacteria L Transposase DDE domain group 1 - - - - - - - - - - - - DDE_Tnp_1_4 k141_19040_1 218284.CCDN010000001_gene1173 3.77e-65 220.0 COG0699@1|root,COG0699@2|Bacteria,1TR0Q@1239|Firmicutes,4HBAC@91061|Bacilli,1ZAXM@1386|Bacillus 91061|Bacilli S Dynamin family ypbR GO:0000910,GO:0003674,GO:0003824,GO:0003924,GO:0005575,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022402,GO:0022607,GO:0031224,GO:0032506,GO:0044085,GO:0044425,GO:0051301,GO:0071840,GO:0090529 - - - - - - - - - - Dynamin_N k141_5968_2 1294265.JCM21738_1972 1.47e-64 197.0 COG0640@1|root,COG0640@2|Bacteria,1VA6G@1239|Firmicutes,4HKYT@91061|Bacilli,1ZGXI@1386|Bacillus 91061|Bacilli K transcriptional czrA - - ko:K22043 - - - - ko00000,ko03000 - - - HTH_5 k141_33308_1 1462526.BN990_01765 6.67e-33 116.0 2DN05@1|root,32UP3@2|Bacteria,1VCTK@1239|Firmicutes,4HMNT@91061|Bacilli,4C5Z4@84406|Virgibacillus 91061|Bacilli S Post-transcriptional regulator comN - - - - - - - - - - - Post_transc_reg k141_33308_2 866895.HBHAL_3635 3.73e-28 114.0 COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,1TQVT@1239|Firmicutes,4HB6K@91061|Bacilli,3NDMI@45667|Halobacillus 91061|Bacilli U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secD GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD_SecF,Sec_GG k141_16655_1 218284.CCDN010000005_gene3425 2.92e-110 324.0 COG0492@1|root,COG0492@2|Bacteria,1TRPN@1239|Firmicutes,4H9V7@91061|Bacilli,1ZCEZ@1386|Bacillus 91061|Bacilli C reductase yumC - 1.18.1.2,1.19.1.1 ko:K21567 - - - - ko00000,ko01000 - - iYO844.BSU32110 Pyr_redox_2 k141_29732_1 1116375.VEJY3_00265 3.12e-138 400.0 COG1249@1|root,COG1249@2|Bacteria,1MU2Z@1224|Proteobacteria,1RMC0@1236|Gammaproteobacteria,1XTC6@135623|Vibrionales 135623|Vibrionales C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family gor - 1.8.1.7 ko:K00383 ko00480,ko04918,map00480,map04918 - R00094,R00115 RC00011 ko00000,ko00001,ko01000 - - - Pyr_redox_2,Pyr_redox_dim k141_29732_2 1219076.N646_2246 1.46e-138 392.0 COG0800@1|root,COG0800@2|Bacteria,1MUVJ@1224|Proteobacteria,1RPDF@1236|Gammaproteobacteria,1XU29@135623|Vibrionales 135623|Vibrionales G COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase eda - 4.1.2.14,4.1.3.42 ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 M00008,M00061,M00308,M00631 R00470,R05605 RC00307,RC00308,RC00435 ko00000,ko00001,ko00002,ko01000 - - - Aldolase k141_29732_3 1219076.N646_2245 8.51e-261 723.0 COG2610@1|root,COG2610@2|Bacteria,1MUFG@1224|Proteobacteria,1RNGE@1236|Gammaproteobacteria,1XVND@135623|Vibrionales 135623|Vibrionales EG COG2610 H gluconate symporter and related permeases - - - ko:K03299 - - - - ko00000,ko02000 2.A.8 - - GntP_permease k141_29732_4 223926.28805045 2.7e-104 303.0 COG3265@1|root,COG3265@2|Bacteria,1RHD0@1224|Proteobacteria,1S2UE@1236|Gammaproteobacteria,1XSJW@135623|Vibrionales 135623|Vibrionales F Gluconokinase idnK - 2.7.1.12 ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 - R01737 RC00002,RC00017 ko00000,ko00001,ko01000 - - - SKI k141_29732_5 1116375.VEJY3_00240 0.0 1079.0 COG0129@1|root,COG0129@2|Bacteria,1MU3T@1224|Proteobacteria,1RMNA@1236|Gammaproteobacteria,1XTAD@135623|Vibrionales 135623|Vibrionales EG Belongs to the IlvD Edd family edd - 4.2.1.12 ko:K01690 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 M00008 R02036 RC00543 ko00000,ko00001,ko00002,ko01000 - - - ILVD_EDD k141_29732_6 1116375.VEJY3_00235 6.4e-217 601.0 COG1609@1|root,COG1609@2|Bacteria,1MUEP@1224|Proteobacteria,1RQKH@1236|Gammaproteobacteria,1XUF7@135623|Vibrionales 135623|Vibrionales K Gluconate utilization system Gnt-I transcriptional repressor gntR - - ko:K06145 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_1,Peripla_BP_3 k141_13097_1 713586.KB900536_gene1479 1.38e-26 112.0 COG2067@1|root,COG2067@2|Bacteria 2|Bacteria I long-chain fatty acid transporting porin activity - - - ko:K06076 - - - - ko00000,ko02000 1.B.9 - - Toluene_X k141_28557_1 1168065.DOK_10657 1.8e-07 52.8 COG2111@1|root,COG2111@2|Bacteria,1N1CK@1224|Proteobacteria,1RR3K@1236|Gammaproteobacteria,1J5HN@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P COG2111 Multisubunit Na H antiporter, MnhB subunit - - - ko:K05566 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - DUF4040,MnhB k141_28557_2 1042377.AFPJ01000024_gene705 9.37e-59 185.0 COG1006@1|root,COG1006@2|Bacteria,1RGU1@1224|Proteobacteria,1S6BB@1236|Gammaproteobacteria,467Z5@72275|Alteromonadaceae 1236|Gammaproteobacteria P NADH-ubiquinone/plastoquinone oxidoreductase chain 4L - - - ko:K05567 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - Oxidored_q2 k141_23798_1 1294265.JCM21738_2187 9.51e-127 366.0 COG2159@1|root,COG2159@2|Bacteria,1UXYD@1239|Firmicutes,4HDAD@91061|Bacilli,1ZDX2@1386|Bacillus 91061|Bacilli S Amidohydrolase - - 4.1.1.45,4.1.1.52 ko:K03392,ko:K22213 ko00380,ko01100,map00380,map01100 M00038 R04323 RC00779 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_2 k141_34497_1 935836.JAEL01000035_gene1957 1.52e-96 284.0 COG0454@1|root,COG0456@2|Bacteria,1TSZY@1239|Firmicutes,4HAYD@91061|Bacilli,1ZD7N@1386|Bacillus 91061|Bacilli K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases yjbC - - - - - - - - - - - Acetyltransf_7 k141_29741_2 674977.VMC_10000 1.16e-202 561.0 COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,1RMGQ@1236|Gammaproteobacteria,1XSUC@135623|Vibrionales 135623|Vibrionales M Belongs to the KdsA family kdsA GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005996,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008676,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016053,GO:0016740,GO:0016765,GO:0019294,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0046364,GO:0046394,GO:0046400,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.5.1.55 ko:K01627 ko00540,ko01100,map00540,map01100 M00063 R03254 RC00435 ko00000,ko00001,ko00002,ko01000,ko01005 - - - DAHP_synth_1 k141_29741_3 1116375.VEJY3_03430 2.92e-189 526.0 COG2912@1|root,COG2912@2|Bacteria,1MVJQ@1224|Proteobacteria,1RQ7V@1236|Gammaproteobacteria,1XSET@135623|Vibrionales 135623|Vibrionales S Transglutaminase-like superfamily ychA - - - - - - - - - - - TPR_9,Transglut_core2 k141_29741_4 223926.28805731 2.82e-81 241.0 COG3094@1|root,COG3094@2|Bacteria,1N50P@1224|Proteobacteria,1SAX6@1236|Gammaproteobacteria,1XXDI@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria sirB - - - - - - - - - - - SirB k141_29741_5 223926.28805730 6.75e-185 516.0 COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,1RNGK@1236|Gammaproteobacteria,1XTR8@135623|Vibrionales 135623|Vibrionales J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif prmC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 ko:K02493 - - R10806 RC00003,RC03279 ko00000,ko01000,ko03012 - - - Methyltransf_31 k141_29741_6 1116375.VEJY3_03415 1.88e-250 688.0 COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,1RM7Q@1236|Gammaproteobacteria,1XTF3@135623|Vibrionales 135623|Vibrionales J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA prfA GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02835 - - - - ko00000,ko03012 - - - PCRF,RF-1 k141_29741_7 1116375.VEJY3_03410 4.58e-59 193.0 COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,1RNQ8@1236|Gammaproteobacteria,1XTUS@135623|Vibrionales 135623|Vibrionales H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) hemA GO:0003674,GO:0003824,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0008883,GO:0009058,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.2.1.70 ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R04109 RC00055,RC00149 ko00000,ko00001,ko00002,ko01000 - - - GlutR_N,GlutR_dimer,Shikimate_DH k141_28594_2 218284.CCDN010000001_gene628 1.59e-106 311.0 COG0850@1|root,COG0850@2|Bacteria,1VAPC@1239|Firmicutes,4HBTI@91061|Bacilli,1ZDSJ@1386|Bacillus 91061|Bacilli D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization minC GO:0000910,GO:0003674,GO:0004857,GO:0007049,GO:0007105,GO:0008150,GO:0009987,GO:0022402,GO:0030234,GO:0031333,GO:0032271,GO:0032272,GO:0032506,GO:0043086,GO:0043254,GO:0044087,GO:0044092,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0065007,GO:0065009,GO:0098772 - ko:K03610 - - - - ko00000,ko03036,ko04812 - - - MinC_C k141_1203_1 218284.CCDN010000001_gene1570 5.02e-102 312.0 COG1960@1|root,COG1960@2|Bacteria,1TQC8@1239|Firmicutes,4HC6Y@91061|Bacilli,1ZCXT@1386|Bacillus 91061|Bacilli I Acyl-CoA dehydrogenase, middle domain - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M k141_14316_1 218284.CCDN010000001_gene1067 5.53e-108 317.0 COG0739@1|root,COG0739@2|Bacteria,1V3ZU@1239|Firmicutes,4I27X@91061|Bacilli,1ZGNS@1386|Bacillus 91061|Bacilli M COG0739 Membrane proteins related to metalloendopeptidases - - - - - - - - - - - - LysM,Peptidase_M23 k141_7153_2 1279017.AQYJ01000020_gene1216 4.02e-182 513.0 COG0524@1|root,COG0524@2|Bacteria,1MUUC@1224|Proteobacteria,1RMN2@1236|Gammaproteobacteria,464Y8@72275|Alteromonadaceae 1236|Gammaproteobacteria G pfkB family carbohydrate kinase gsk GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008906,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237 2.7.1.15,2.7.1.4,2.7.1.73 ko:K00847,ko:K00852,ko:K00892 ko00030,ko00051,ko00230,ko00500,ko00520,ko01100,map00030,map00051,map00230,map00500,map00520,map01100 - R00760,R00867,R01051,R01131,R01228,R02750,R03920 RC00002,RC00017 ko00000,ko00001,ko01000 - - iSDY_1059.SDY_0442 PfkB k141_7153_3 1279017.AQYJ01000020_gene1217 1.94e-274 768.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,464Y3@72275|Alteromonadaceae 1236|Gammaproteobacteria T GGDEF domain - - - - - - - - - - - - 7TMR-DISMED2,EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9 k141_7153_4 1042377.AFPJ01000032_gene2702 2.16e-74 229.0 COG3056@1|root,COG3056@2|Bacteria,1N9MP@1224|Proteobacteria,1SAXB@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Uncharacterized lipoprotein - - - ko:K07286 - - - - ko00000 - - - Lipoprotein_16 k141_7153_5 1248760.ANFZ01000009_gene1021 1.17e-09 60.8 COG2847@1|root,COG2847@2|Bacteria,1N3BG@1224|Proteobacteria,2UM57@28211|Alphaproteobacteria,2K60Y@204457|Sphingomonadales 204457|Sphingomonadales S Copper chaperone PCu(A)C - - - ko:K09796 - - - - ko00000,ko03110 - - - PCuAC k141_7153_6 1279017.AQYJ01000020_gene1220 2.6e-80 248.0 COG3063@1|root,COG3063@2|Bacteria,1N54A@1224|Proteobacteria,1T30X@1236|Gammaproteobacteria,4683A@72275|Alteromonadaceae 1236|Gammaproteobacteria NU Type IV pilus biogenesis stability protein PilW - - - - - - - - - - - - - k141_7153_7 1279017.AQYJ01000020_gene1221 5.32e-255 719.0 COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,1RPF7@1236|Gammaproteobacteria,46550@72275|Alteromonadaceae 1236|Gammaproteobacteria CO Thiol disulfide interchange protein dsbD - 1.8.1.8 ko:K04084 - - - - ko00000,ko01000,ko03110 5.A.1.1 - - DsbC,DsbD,Thioredoxin_7 k141_7153_8 1124983.PFLCHA0_c06830 2.1e-66 207.0 COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,1S3PX@1236|Gammaproteobacteria,1YPGV@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria E Catalyzes a trans-dehydration via an enolate intermediate aroQ - 4.2.1.10 ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03084 RC00848 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_0560 DHquinase_II k141_7153_9 1279017.AQYJ01000020_gene1223 4.34e-69 213.0 COG0511@1|root,COG0511@2|Bacteria,1RCXA@1224|Proteobacteria,1S3YP@1236|Gammaproteobacteria,466TN@72275|Alteromonadaceae 1236|Gammaproteobacteria I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA accB GO:0003674,GO:0003824,GO:0003989,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009305,GO:0009987,GO:0016049,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901576 - ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742 RC00040,RC00367 ko00000,ko00001,ko00002 - - iYL1228.KPN_03664 Biotin_lipoyl k141_7153_10 1453501.JELR01000002_gene1515 3.07e-301 824.0 COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,1RMNB@1236|Gammaproteobacteria,46537@72275|Alteromonadaceae 1236|Gammaproteobacteria I Biotin carboxylase accC GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - iSF_1195.SF3294 Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 k141_34513_1 1294265.JCM21738_1161 7.4e-114 329.0 COG0775@1|root,COG0775@2|Bacteria,1U7WK@1239|Firmicutes,4HB8K@91061|Bacilli,1ZB7T@1386|Bacillus 91061|Bacilli E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively mtnN - 3.2.2.9 ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 M00034,M00609 R00194,R01401 RC00063,RC00318 ko00000,ko00001,ko00002,ko01000 - - - PNP_UDP_1 k141_4815_1 218284.CCDN010000001_gene1000 1.72e-45 159.0 COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,4HC50@91061|Bacilli,1ZQ98@1386|Bacillus 91061|Bacilli I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) yqjD GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016421,GO:0016874,GO:0016885,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0071704,GO:0072329,GO:1901575 2.1.3.15,6.4.1.3 ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 M00373,M00741 R01859 RC00097,RC00609 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans k141_4815_2 218284.CCDN010000001_gene1001 6.89e-79 244.0 COG2195@1|root,COG2195@2|Bacteria,1TP3A@1239|Firmicutes,4HA04@91061|Bacilli,1ZBSY@1386|Bacillus 91061|Bacilli E COG2195 Di- and tripeptidases yqjE - 3.4.11.14,3.4.11.4 ko:K01258,ko:K01263 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20,Peptidase_M28 k141_32127_1 1122927.KB895415_gene4563 6.63e-19 84.7 COG0491@1|root,COG0491@2|Bacteria,1V0KE@1239|Firmicutes,4HEH9@91061|Bacilli,275BM@186822|Paenibacillaceae 91061|Bacilli S Metal-dependent hydrolase - - - - - - - - - - - - Lactamase_B k141_32127_3 666686.B1NLA3E_13555 5.32e-68 210.0 COG4894@1|root,COG4894@2|Bacteria,1V3WA@1239|Firmicutes,4IR1G@91061|Bacilli,1ZBFD@1386|Bacillus 91061|Bacilli S LURP-one-related yxjI - - - - - - - - - - - LOR k141_11921_1 1279017.AQYJ01000025_gene574 1.69e-91 275.0 COG4795@1|root,COG4795@2|Bacteria,1RJAE@1224|Proteobacteria,1S5ZZ@1236|Gammaproteobacteria,466QM@72275|Alteromonadaceae 1236|Gammaproteobacteria U General secretion pathway protein J gspJ GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0098776 - ko:K02459 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - N_methyl,T2SSJ k141_11921_2 1453501.JELR01000001_gene2381 4.05e-46 153.0 COG2165@1|root,COG2165@2|Bacteria,1N737@1224|Proteobacteria,1SC8X@1236|Gammaproteobacteria,468WY@72275|Alteromonadaceae 1236|Gammaproteobacteria NU General secretion pathway protein I gspI GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - ko:K02458 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - N_methyl,T2SSI k141_11921_3 1279017.AQYJ01000025_gene576 1.65e-33 122.0 COG2165@1|root,COG2165@2|Bacteria 2|Bacteria NU general secretion pathway protein gspH - - ko:K02457,ko:K02650 ko02020,ko03070,ko05111,map02020,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 - - GspH,N_methyl k141_30960_2 1042377.AFPJ01000005_gene2478 8.11e-227 635.0 COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,1RMEN@1236|Gammaproteobacteria,463Y3@72275|Alteromonadaceae 1236|Gammaproteobacteria U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family gltT - - ko:K03309 - - - - ko00000 2.A.23 - - SDF k141_30960_3 1279017.AQYJ01000027_gene1875 2.43e-79 242.0 COG3161@1|root,COG3161@2|Bacteria,1N8BF@1224|Proteobacteria,1SDX2@1236|Gammaproteobacteria,46867@72275|Alteromonadaceae 1236|Gammaproteobacteria H Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway ubiC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008813,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.1.3.40 ko:K03181 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R01302 RC00491,RC02148 ko00000,ko00001,ko00002,ko01000 - - iZ_1308.Z5638 Chor_lyase k141_30960_4 1042377.AFPJ01000005_gene2476 3.82e-170 479.0 COG0382@1|root,COG0382@2|Bacteria,1MV4Q@1224|Proteobacteria,1RMZ1@1236|Gammaproteobacteria,46476@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate ubiA GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008412,GO:0009058,GO:0009108,GO:0009987,GO:0016020,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901576,GO:1901661,GO:1901663 2.5.1.39 ko:K03179 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R05000,R05615 RC00209,RC02895 ko00000,ko00001,ko00002,ko01000,ko01006 - - iZ_1308.Z5639 UbiA k141_30960_5 1453501.JELR01000002_gene1188 1.76e-155 438.0 COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,1RN41@1236|Gammaproteobacteria,464AU@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain phoB GO:0001098,GO:0001108,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042802,GO:0043254,GO:0044087,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - ko:K07657 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C k141_30960_6 1453501.JELR01000002_gene1187 3.83e-243 676.0 COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,1RN0F@1236|Gammaproteobacteria,465EB@72275|Alteromonadaceae 1236|Gammaproteobacteria T Signal transduction histidine kinase phoR - 2.7.13.3 ko:K07636 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - DUF3329,HATPase_c,HisKA,PAS,PAS_8 k141_27369_1 1042377.AFPJ01000034_gene2331 2.74e-90 269.0 COG3117@1|root,COG3117@2|Bacteria,1NGCC@1224|Proteobacteria,1SGDP@1236|Gammaproteobacteria,468M6@72275|Alteromonadaceae 1236|Gammaproteobacteria S Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA lptC - - ko:K11719 - - - - ko00000,ko02000 1.B.42.1 - - LptC k141_27369_3 1279017.AQYJ01000024_gene1042 1.3e-153 433.0 COG1137@1|root,COG1137@2|Bacteria,1MU8M@1224|Proteobacteria,1RPW1@1236|Gammaproteobacteria,464GB@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG1137 ABC-type (unclassified) transport system, ATPase component lptB GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - ko:K06861 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko01000,ko02000 1.B.42.1 - - ABC_tran,BCA_ABC_TP_C k141_27369_4 1042377.AFPJ01000034_gene2328 3.42e-254 708.0 COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,1RMY0@1236|Gammaproteobacteria,4642B@72275|Alteromonadaceae 1236|Gammaproteobacteria K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released rpoN GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0042802,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - ko:K03092 ko02020,ko05111,map02020,map05111 - - - ko00000,ko00001,ko03021 - - - Sigma54_AID,Sigma54_CBD,Sigma54_DBD k141_27369_6 1042377.AFPJ01000034_gene2326 2.39e-90 266.0 COG1762@1|root,COG1762@2|Bacteria,1RD0E@1224|Proteobacteria,1S668@1236|Gammaproteobacteria,46810@72275|Alteromonadaceae 1236|Gammaproteobacteria G COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type) ptsN GO:0001932,GO:0001934,GO:0003674,GO:0003824,GO:0004857,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0008047,GO:0008150,GO:0008643,GO:0009401,GO:0009893,GO:0010033,GO:0010243,GO:0010562,GO:0010604,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0019207,GO:0019209,GO:0019220,GO:0019222,GO:0019887,GO:0022804,GO:0022857,GO:0022898,GO:0030234,GO:0030295,GO:0031323,GO:0031325,GO:0031399,GO:0031401,GO:0032147,GO:0032268,GO:0032270,GO:0032409,GO:0032412,GO:0032879,GO:0033674,GO:0034219,GO:0034762,GO:0034765,GO:0042221,GO:0042325,GO:0042327,GO:0043085,GO:0043086,GO:0043269,GO:0043549,GO:0044092,GO:0044093,GO:0044424,GO:0044444,GO:0044464,GO:0045859,GO:0045860,GO:0045937,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051049,GO:0051171,GO:0051173,GO:0051174,GO:0051179,GO:0051234,GO:0051246,GO:0051247,GO:0051338,GO:0051347,GO:0055085,GO:0060255,GO:0065007,GO:0065009,GO:0071702,GO:0071944,GO:0080090,GO:0090563,GO:0098772,GO:1901698 - ko:K02806 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 - - - PTS_EIIA_2 k141_27369_7 1453501.JELR01000001_gene3089 2.19e-178 500.0 COG1660@1|root,COG1660@2|Bacteria,1MVX6@1224|Proteobacteria,1RNJX@1236|Gammaproteobacteria,464DI@72275|Alteromonadaceae 1236|Gammaproteobacteria S Displays ATPase and GTPase activities rapZ GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - ko:K06958 - - - - ko00000,ko03019 - - - ATP_bind_2 k141_27369_9 1453501.JELR01000001_gene3091 4.57e-245 682.0 COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,1RNE4@1236|Gammaproteobacteria,4641S@72275|Alteromonadaceae 1236|Gammaproteobacteria P Acts as a magnesium transporter mgtE - - ko:K06213 - - - - ko00000,ko02000 1.A.26.1 - - CBS,MgtE,MgtE_N k141_27369_10 1279017.AQYJ01000024_gene1035 7.8e-79 238.0 COG3028@1|root,COG3028@2|Bacteria,1MZ4R@1224|Proteobacteria,1S9JJ@1236|Gammaproteobacteria,467RH@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the UPF0307 family yjgA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K09889 - - - - ko00000,ko03009 - - - DUF615 k141_27369_12 1279017.AQYJ01000024_gene1034 3.43e-86 258.0 COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,1S4G5@1236|Gammaproteobacteria,467J4@72275|Alteromonadaceae 1236|Gammaproteobacteria O SelR domain - - 1.8.4.12 ko:K07305 - - - - ko00000,ko01000 - - - SelR k141_27369_13 1279017.AQYJ01000024_gene1033 0.0 1529.0 COG3164@1|root,COG3164@2|Bacteria,1MXWF@1224|Proteobacteria,1RNUK@1236|Gammaproteobacteria,464CY@72275|Alteromonadaceae 1236|Gammaproteobacteria S membrane yhdP GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0042597,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - - - - - - - - - - AsmA_2,DUF3971 k141_26207_1 218284.CCDN010000001_gene1211 5.54e-109 314.0 COG2190@1|root,COG2190@2|Bacteria,1VAEB@1239|Firmicutes,4HIPR@91061|Bacilli,1ZG91@1386|Bacillus 91061|Bacilli G COG2190 Phosphotransferase system IIA components crr - - ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 M00265,M00266,M00268,M00270,M00272,M00303,M00806 R02738,R02780,R04111,R04394,R05132,R08559 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.1 - - PTS_EIIA_1 k141_7154_1 314265.R2601_00845 0.000823 40.8 COG0471@1|root,COG0471@2|Bacteria,1MU0K@1224|Proteobacteria,2TSFS@28211|Alphaproteobacteria 28211|Alphaproteobacteria P COG0471 Di- and tricarboxylate transporters - - - - - - - - - - - - CitMHS,TrkA_C k141_7154_2 501479.ACNW01000051_gene3449 2.99e-45 157.0 COG0621@1|root,COG0621@2|Bacteria,1MU7N@1224|Proteobacteria,2TQUS@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 rimO - 2.8.4.4 ko:K14441 - - R10652 RC00003,RC03217 ko00000,ko01000,ko03009 - - - Radical_SAM,TRAM,UPF0004 k141_33330_1 1123251.ATWM01000009_gene2850 3.37e-91 283.0 COG2987@1|root,COG2987@2|Bacteria,2GP10@201174|Actinobacteria,4FERC@85021|Intrasporangiaceae 201174|Actinobacteria E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate hutU - 4.2.1.49 ko:K01712 ko00340,ko01100,map00340,map01100 M00045 R02914 RC00804 ko00000,ko00001,ko00002,ko01000 - - - Urocanase,Urocanase_C,Urocanase_N k141_19061_1 218284.CCDN010000001_gene965 6.96e-62 191.0 COG0781@1|root,COG0781@2|Bacteria,1VA9B@1239|Firmicutes,4HKMU@91061|Bacilli,1ZH3P@1386|Bacillus 91061|Bacilli K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons nusB - - ko:K03625 - - - - ko00000,ko03009,ko03021 - - - NusB k141_19061_2 218284.CCDN010000001_gene966 1.38e-36 130.0 COG0190@1|root,COG0190@2|Bacteria,1TP1P@1239|Firmicutes,4H9Q6@91061|Bacilli,1ZC9G@1386|Bacillus 91061|Bacilli F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate folD GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R01220,R01655 RC00202,RC00578 ko00000,ko00001,ko00002,ko01000 - - - THF_DHG_CYH,THF_DHG_CYH_C k141_35718_1 218284.CCDN010000006_gene3514 3.77e-275 771.0 COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1TR8J@1239|Firmicutes,4H9XN@91061|Bacilli,1ZATV@1386|Bacillus 91061|Bacilli I 3-hydroxyacyl-CoA dehydrogenase fadN - 1.1.1.35 ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 M00087 R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU32840 3HCDH,3HCDH_N,ECH_1 k141_35718_2 218284.CCDN010000006_gene3513 2.4e-09 57.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,1ZBKX@1386|Bacillus 91061|Bacilli I Belongs to the thiolase family fadA - 2.3.1.16 ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 M00087,M00113 R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095 RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955 ko00000,ko00001,ko00002,ko01000 - - - Thiolase_C,Thiolase_N k141_14318_1 1453501.JELR01000002_gene920 2.19e-112 325.0 COG1272@1|root,COG1272@2|Bacteria,1PGRH@1224|Proteobacteria,1RR4R@1236|Gammaproteobacteria,467AP@72275|Alteromonadaceae 1236|Gammaproteobacteria S membrane protein, hemolysin III homolog yqfA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K11068 - - - - ko00000,ko02042 - - - HlyIII k141_55_1 861299.J421_3838 5.13e-40 149.0 COG0737@1|root,COG0737@2|Bacteria,1ZTEA@142182|Gemmatimonadetes 142182|Gemmatimonadetes F 5'-nucleotidase, C-terminal domain - - 3.1.3.5 ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - 5_nucleotid_C,Metallophos k141_28595_1 94624.Bpet3888 4.16e-39 133.0 COG3832@1|root,COG3832@2|Bacteria,1RCZK@1224|Proteobacteria,2VR7G@28216|Betaproteobacteria,3T3YV@506|Alcaligenaceae 28216|Betaproteobacteria S Activator of Hsp90 ATPase homolog 1-like protein - - - - - - - - - - - - AHSA1 k141_28595_2 1453501.JELR01000002_gene729 9.48e-68 206.0 2DBI3@1|root,32TXG@2|Bacteria,1RF32@1224|Proteobacteria,1SR7F@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_28595_3 795666.MW7_0372 1.18e-75 231.0 COG0503@1|root,COG0503@2|Bacteria,1MVZ6@1224|Proteobacteria,2VI7G@28216|Betaproteobacteria,1K1XQ@119060|Burkholderiaceae 28216|Betaproteobacteria F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis apt GO:0000166,GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0003999,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0012505,GO:0016192,GO:0016208,GO:0016740,GO:0016757,GO:0016763,GO:0017076,GO:0018130,GO:0019438,GO:0030141,GO:0030554,GO:0031410,GO:0031974,GO:0031981,GO:0031982,GO:0031983,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0034641,GO:0034654,GO:0034774,GO:0036094,GO:0036230,GO:0042119,GO:0043094,GO:0043101,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0046483,GO:0046903,GO:0050896,GO:0051179,GO:0051234,GO:0060205,GO:0070013,GO:0071704,GO:0072521,GO:0072522,GO:0097159,GO:0097367,GO:0097708,GO:0099503,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.4.2.7 ko:K00759 ko00230,ko01100,map00230,map01100 - R00190,R01229,R04378 RC00063 ko00000,ko00001,ko01000,ko04147 - - - Pribosyltran k141_9535_1 1453501.JELR01000002_gene692 1.14e-58 189.0 COG0517@1|root,COG0517@2|Bacteria,1RJTX@1224|Proteobacteria,1S6K2@1236|Gammaproteobacteria,467TZ@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0517 FOG CBS domain - - - - - - - - - - - - CBS k141_21443_1 218284.CCDN010000006_gene3531 2.88e-78 241.0 COG0673@1|root,COG0673@2|Bacteria,1TR8S@1239|Firmicutes,4HBHI@91061|Bacilli,1ZDU7@1386|Bacillus 91061|Bacilli S Oxidoreductase yvaA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0070401,GO:0070402,GO:0097159,GO:0102497,GO:1901265,GO:1901363 1.1.1.371 ko:K16044 ko00562,ko01120,map00562,map01120 - R09954 RC00182 ko00000,ko00001,ko01000 - - - GFO_IDH_MocA,GFO_IDH_MocA_C k141_20398_1 270374.MELB17_21395 3.68e-60 196.0 COG0715@1|root,COG0715@2|Bacteria,1R5S6@1224|Proteobacteria,1RZSB@1236|Gammaproteobacteria 1236|Gammaproteobacteria P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1_2 k141_16928_1 1453501.JELR01000001_gene2874 9.51e-143 412.0 COG0053@1|root,COG0053@2|Bacteria,1MVH8@1224|Proteobacteria,1RQ3E@1236|Gammaproteobacteria,46BQ5@72275|Alteromonadaceae 1236|Gammaproteobacteria U Cation efflux family catA - - - - - - - - - - - Cation_efflux,ZT_dimer k141_27542_1 314287.GB2207_00070 5.52e-45 164.0 COG4773@1|root,COG4773@2|Bacteria,1MWUQ@1224|Proteobacteria,1SJYF@1236|Gammaproteobacteria 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec k141_1407_2 674977.VMC_41900 4.52e-63 193.0 COG3695@1|root,COG3695@2|Bacteria,1N7J2@1224|Proteobacteria,1SCIZ@1236|Gammaproteobacteria,1XXXX@135623|Vibrionales 135623|Vibrionales L methylated DNA-protein cysteine methyltransferase - - - ko:K07443 - - - - ko00000 - - - DNA_binding_1 k141_1407_3 1116375.VEJY3_04345 1.37e-87 258.0 COG3126@1|root,COG3126@2|Bacteria,1N8AF@1224|Proteobacteria,1SCM7@1236|Gammaproteobacteria,1XYJI@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria - - - ko:K09914 - - - - ko00000 - - - YscW k141_1407_4 1116375.VEJY3_04340 1.3e-205 568.0 COG1946@1|root,COG1946@2|Bacteria,1MV9R@1224|Proteobacteria,1RPFI@1236|Gammaproteobacteria,1XU39@135623|Vibrionales 135623|Vibrionales I Acyl-CoA thioesterase tesB - - ko:K10805 ko01040,map01040 - - - ko00000,ko00001,ko01000,ko01004 - - - 4HBT_3 k141_1407_5 1116375.VEJY3_04335 1.63e-104 302.0 COG1522@1|root,COG1522@2|Bacteria,1RDB3@1224|Proteobacteria,1S2E1@1236|Gammaproteobacteria,1XWVX@135623|Vibrionales 135623|Vibrionales K Transcriptional regulator AsnC family ybaO - - ko:K05800 - - - - ko00000,ko03000 - - - AsnC_trans_reg,HTH_24,HTH_AsnC-type k141_1407_6 945550.VISI1226_21589 1.71e-118 346.0 COG0031@1|root,COG0031@2|Bacteria,1MUR6@1224|Proteobacteria,1RMS1@1236|Gammaproteobacteria,1XUZT@135623|Vibrionales 135623|Vibrionales E Cysteine synthase - - 2.5.1.47 ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03601,R04859 RC00020,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 - - - PALP k141_25235_1 218284.CCDN010000005_gene3243 7.83e-100 295.0 COG1562@1|root,COG1562@2|Bacteria,1TQHF@1239|Firmicutes,4HA1A@91061|Bacilli,1ZCIV@1386|Bacillus 91061|Bacilli I phytoene crtM - 2.5.1.32,2.5.1.99 ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 M00097 R02065,R04218,R07270,R10177 RC00362,RC01101,RC02869 ko00000,ko00001,ko00002,ko01000,ko01006 - - - SQS_PSY k141_22862_2 1453501.JELR01000001_gene3094 1.48e-61 188.0 COG3526@1|root,COG3526@2|Bacteria,1MZ5V@1224|Proteobacteria,1S8S8@1236|Gammaproteobacteria,468BE@72275|Alteromonadaceae 1236|Gammaproteobacteria O protein conserved in bacteria - - - ko:K07401 - - - - ko00000 - - - Rdx k141_26540_1 1453501.JELR01000002_gene609 4.24e-33 121.0 COG1409@1|root,COG1409@2|Bacteria,1MWKX@1224|Proteobacteria,1RPA7@1236|Gammaproteobacteria,466SM@72275|Alteromonadaceae 1236|Gammaproteobacteria S Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes cpdA GO:0003674,GO:0003824,GO:0004112,GO:0004114,GO:0004115,GO:0005488,GO:0005506,GO:0008081,GO:0008150,GO:0008198,GO:0009987,GO:0016043,GO:0016787,GO:0016788,GO:0042545,GO:0042578,GO:0043167,GO:0043169,GO:0045229,GO:0046872,GO:0046914,GO:0071554,GO:0071555,GO:0071840 3.1.4.53 ko:K03651 ko00230,ko02025,map00230,map02025 - R00191 RC00296 ko00000,ko00001,ko01000 - - - Metallophos k141_26540_2 1453501.JELR01000002_gene610 2.41e-51 166.0 COG3151@1|root,COG3151@2|Bacteria,1RA4E@1224|Proteobacteria,1S55I@1236|Gammaproteobacteria,468KM@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria yqiB - - ko:K09920 - - - - ko00000 - - - DUF1249 k141_9740_2 218284.CCDN010000005_gene3365 3.67e-83 261.0 COG1032@1|root,COG1032@2|Bacteria,1TPGT@1239|Firmicutes,4HA0Y@91061|Bacilli,1ZAU7@1386|Bacillus 91061|Bacilli C Fe-S oxidoreductase bchE - 1.21.98.3 ko:K04034 ko00860,ko01100,ko01110,map00860,map01100,map01110 - R06268,R06269,R06270 RC00741,RC01491,RC01492 ko00000,ko00001,ko01000 - - - B12-binding,DUF4080,Radical_SAM k141_21688_1 1379270.AUXF01000002_gene1485 2.35e-35 133.0 COG0491@1|root,COG0491@2|Bacteria 2|Bacteria GM Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid blaB3 - - - - - - - - - - - Lactamase_B k141_21688_2 261292.Nit79A3_1628 5.64e-10 62.4 COG3474@1|root,COG3474@2|Bacteria,1QWSY@1224|Proteobacteria,2WH7U@28216|Betaproteobacteria 28216|Betaproteobacteria C Cytochrome P460 - - - - - - - - - - - - Cytochrome_P460 k141_26541_1 717606.PaecuDRAFT_1720 0.000152 42.4 COG0346@1|root,COG0346@2|Bacteria,1VAEF@1239|Firmicutes,4HGTX@91061|Bacilli,26YD6@186822|Paenibacillaceae 91061|Bacilli E Glyoxalase bleomycin resistance protein dioxygenase - - - - - - - - - - - - Glyoxalase k141_26541_2 1131730.BAVI_21038 4.31e-51 172.0 COG0477@1|root,COG2814@2|Bacteria,1TRDJ@1239|Firmicutes,4H9Q9@91061|Bacilli,1ZBN7@1386|Bacillus 91061|Bacilli EGP Major facilitator superfamily yuxJ - - - - - - - - - - - MFS_1,Sugar_tr k141_4984_1 1042377.AFPJ01000050_gene1321 1.62e-69 213.0 COG2606@1|root,COG2606@2|Bacteria,1N10Y@1224|Proteobacteria,1SAQE@1236|Gammaproteobacteria 1236|Gammaproteobacteria S YbaK prolyl-tRNA synthetase associated - - - ko:K19055 - - - - ko00000,ko01000,ko03016 - - - tRNA_edit k141_4984_3 1042377.AFPJ01000055_gene1006 6.08e-119 343.0 COG0087@1|root,COG0087@2|Bacteria,1MUST@1224|Proteobacteria,1RMK9@1236|Gammaproteobacteria,465E3@72275|Alteromonadaceae 1236|Gammaproteobacteria J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit rplC GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02906 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L3 k141_22863_1 218284.CCDN010000008_gene4137 6.8e-54 186.0 COG0058@1|root,COG0058@2|Bacteria,1TQAJ@1239|Firmicutes,4H9XI@91061|Bacilli,1ZCRF@1386|Bacillus 91061|Bacilli G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties glgP GO:0000272,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005976,GO:0005977,GO:0005980,GO:0006073,GO:0006091,GO:0006112,GO:0008144,GO:0008150,GO:0008152,GO:0008184,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0015980,GO:0016052,GO:0016740,GO:0016757,GO:0016758,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901575 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 - R02111 - ko00000,ko00001,ko01000 - GT35 iYO844.BSU30940 Phosphorylase k141_13383_1 997296.PB1_00975 3.15e-06 52.4 2D5MU@1|root,32TJF@2|Bacteria,1V9ZA@1239|Firmicutes,4HMQI@91061|Bacilli,1ZFEI@1386|Bacillus 91061|Bacilli - - ylxL - - - - - - - - - - - - k141_13383_3 1307436.PBF_07611 6.24e-10 58.9 2EQVH@1|root,33IFA@2|Bacteria,1VKS4@1239|Firmicutes,4HS0N@91061|Bacilli,1ZJ67@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_16931_1 218284.CCDN010000001_gene1305 1.94e-100 296.0 COG3340@1|root,COG3340@2|Bacteria,1TRBA@1239|Firmicutes,4HB19@91061|Bacilli,1ZC4Z@1386|Bacillus 91061|Bacilli E Belongs to the peptidase S51 family ygaJ GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564 3.4.13.21 ko:K05995 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S51 k141_29925_1 218284.CCDN010000001_gene1896 1.27e-63 205.0 COG0743@1|root,COG0743@2|Bacteria,1TP1C@1239|Firmicutes,4HBAV@91061|Bacilli,1ZC3I@1386|Bacillus 91061|Bacilli I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) dxr GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05688 RC01452 ko00000,ko00001,ko00002,ko01000 - - - DXPR_C,DXP_redisom_C,DXP_reductoisom k141_32268_1 218284.CCDN010000005_gene3205 1.03e-123 367.0 COG3290@1|root,COG3290@2|Bacteria,1TQJR@1239|Firmicutes,4H9Q0@91061|Bacilli,1ZBHV@1386|Bacillus 91061|Bacilli T Signal transduction histidine kinase regulating citrate malate metabolism malK - 2.7.13.3 ko:K11614 ko02020,map02020 M00490 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,PAS,SPOB_a,sCache_3_2 k141_21689_1 314275.MADE_1006775 1.06e-24 109.0 COG0457@1|root,COG2304@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,1MW51@1224|Proteobacteria,1RMD3@1236|Gammaproteobacteria,464YJ@72275|Alteromonadaceae 1236|Gammaproteobacteria K protein containing a von Willebrand factor type A (vWA) domain - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - TPR_1,TPR_2,VWA_2 k141_22864_2 1479235.KK366039_gene2992 3.7e-44 154.0 COG0642@1|root,COG2205@2|Bacteria,1QV1H@1224|Proteobacteria,1T4NM@1236|Gammaproteobacteria 1236|Gammaproteobacteria T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA k141_15736_1 1174504.AJTN02000210_gene3303 4.56e-100 291.0 COG0735@1|root,COG0735@2|Bacteria,1V7F0@1239|Firmicutes,4HH78@91061|Bacilli,1ZCPG@1386|Bacillus 91061|Bacilli P Belongs to the Fur family fur GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - ko:K03711 - - - - ko00000,ko03000 - - - FUR k141_15736_2 1294265.JCM21738_18 1.93e-48 154.0 2E9B4@1|root,333IZ@2|Bacteria,1VHUQ@1239|Firmicutes,4HR2C@91061|Bacilli,1ZIY4@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF4227) - - - - - - - - - - - - DUF4227 k141_15736_3 997296.PB1_14369 3.46e-72 225.0 COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,4HAEX@91061|Bacilli,1ZDBF@1386|Bacillus 91061|Bacilli L recombinase XerD xerD - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase k141_31204_1 1117647.M5M_17670 3.73e-98 290.0 28H8Z@1|root,2Z7KS@2|Bacteria,1MW9T@1224|Proteobacteria,1RQV1@1236|Gammaproteobacteria,1J6DS@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Yip1 domain - - - - - - - - - - - - DUF1282 k141_22865_1 1205680.CAKO01000030_gene4915 6.11e-58 190.0 COG1703@1|root,COG1703@2|Bacteria,1R44P@1224|Proteobacteria,2TW2E@28211|Alphaproteobacteria,2JR6W@204441|Rhodospirillales 204441|Rhodospirillales E periplasmic protein kinase ArgK and related GTPases of G3E family - - - ko:K07588 - - - - ko00000,ko01000 - - - ArgK k141_19258_1 218284.CCDN010000002_gene2890 4.12e-138 395.0 COG0614@1|root,COG0614@2|Bacteria,1TQMK@1239|Firmicutes,4HBP4@91061|Bacilli,1ZBTM@1386|Bacillus 91061|Bacilli P ABC transporter fhuD GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 - ko:K02016 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - Peripla_BP_2 k141_26544_1 218284.CCDN010000002_gene2120 3.02e-127 369.0 COG0059@1|root,COG0059@2|Bacteria,1TPI7@1239|Firmicutes,4HADK@91061|Bacilli,1ZCH5@1386|Bacillus 91061|Bacilli EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate ilvC - 1.1.1.86 ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R03051,R04439,R04440,R05068,R05069,R05071 RC00726,RC00836,RC00837,RC01726 ko00000,ko00001,ko00002,ko01000 - - - IlvC,IlvN k141_8588_1 666685.R2APBS1_1421 8.58e-135 399.0 COG2312@1|root,COG2312@2|Bacteria,1MU2S@1224|Proteobacteria,1RNDR@1236|Gammaproteobacteria,1X4PA@135614|Xanthomonadales 135614|Xanthomonadales O Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins - - - - - - - - - - - - Erythro_esteras,PCMT k141_8588_2 225937.HP15_4082 4.72e-123 359.0 COG1024@1|root,COG1024@2|Bacteria,1Q67Q@1224|Proteobacteria,1S1Z5@1236|Gammaproteobacteria,466W9@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1024 Enoyl-CoA hydratase carnithine racemase - - 4.2.1.149,4.2.1.17 ko:K01692,ko:K08299 ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212 M00032,M00087 R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093,R10675 RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 k141_8588_3 439235.Dalk_1394 1.83e-124 389.0 COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,42SZ7@68525|delta/epsilon subdivisions,2WPA5@28221|Deltaproteobacteria,2MKE2@213118|Desulfobacterales 28221|Deltaproteobacteria S Amidohydrolase family - - - - - - - - - - - - Amidohydro_3 k141_16932_4 796940.HMPREF9628_02204 4.46e-20 92.4 COG1349@1|root,COG1349@2|Bacteria,1TSUV@1239|Firmicutes,24CQC@186801|Clostridia,25UGG@186804|Peptostreptococcaceae 186801|Clostridia GK Replication initiator protein A (RepA) N-terminus repA - - - - - - - - - - - RepA_N k141_12220_1 1453501.JELR01000002_gene60 4.79e-118 346.0 COG0583@1|root,COG0583@2|Bacteria,1MUWX@1224|Proteobacteria,1RMVV@1236|Gammaproteobacteria,466MX@72275|Alteromonadaceae 1236|Gammaproteobacteria K Transcriptional regulator - - - ko:K17737 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate k141_12220_2 1279017.AQYJ01000026_gene390 3.09e-116 352.0 COG0365@1|root,COG0365@2|Bacteria,1MUX7@1224|Proteobacteria,1RPGT@1236|Gammaproteobacteria,465WE@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases acsA - 6.2.1.16 ko:K01907 ko00280,ko00650,map00280,map00650 - R01357 RC00004,RC00014 ko00000,ko00001,ko01000,ko01004 - - - ACAS_N,AMP-binding,AMP-binding_C k141_32269_1 218284.CCDN010000001_gene801 5.12e-25 104.0 COG0457@1|root,COG0705@1|root,COG0457@2|Bacteria,COG0705@2|Bacteria,1TQXT@1239|Firmicutes,4HCDF@91061|Bacilli,1ZBV7@1386|Bacillus 91061|Bacilli O membrane protein (homolog of Drosophila rhomboid) gluP - 3.4.21.105 ko:K19225 - - - - ko00000,ko01000,ko01002 - - - Rhomboid,TPR_2,TPR_8 k141_13385_1 218284.CCDN010000001_gene1364 3.13e-95 279.0 2DZ9Y@1|root,32V70@2|Bacteria,1VA6H@1239|Firmicutes,4HKSG@91061|Bacilli,1ZHSJ@1386|Bacillus 91061|Bacilli S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) yhcN - - - - - - - - - - - Spore_YhcN_YlaJ k141_25238_1 218284.CCDN010000001_gene1393 2.4e-138 400.0 COG2309@1|root,COG2309@2|Bacteria,1TP65@1239|Firmicutes,4H9W8@91061|Bacilli,1ZCU3@1386|Bacillus 91061|Bacilli E COG2309 Leucyl aminopeptidase (aminopeptidase T) - - - ko:K19689 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M29 k141_26545_1 1123279.ATUS01000001_gene2281 7.31e-09 56.2 COG2863@1|root,COG2863@2|Bacteria,1N2NB@1224|Proteobacteria,1RZFP@1236|Gammaproteobacteria,1J6DD@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C COG2863 Cytochrome c553 cc4 - - - - - - - - - - - Cytochrom_C,Cytochrome_CBB3 k141_3875_1 1116375.VEJY3_17446 5.56e-36 127.0 COG1418@1|root,COG1418@2|Bacteria,1RB2W@1224|Proteobacteria,1RR38@1236|Gammaproteobacteria,1XX5W@135623|Vibrionales 135623|Vibrionales S HD superfamily hydrolase - - - ko:K06950 - - - - ko00000 - - - HD k141_3875_2 1116375.VEJY3_17441 1.7e-155 439.0 COG3655@1|root,COG3655@2|Bacteria,1RBPK@1224|Proteobacteria,1S22Y@1236|Gammaproteobacteria,1XT81@135623|Vibrionales 135623|Vibrionales K Cro/C1-type HTH DNA-binding domain - - - - - - - - - - - - HTH_26 k141_3875_3 1116375.VEJY3_17436 0.0 1038.0 COG0204@1|root,COG0204@2|Bacteria,1MWDY@1224|Proteobacteria,1RRXF@1236|Gammaproteobacteria,1XVA6@135623|Vibrionales 135623|Vibrionales I COG0477 Permeases of the major facilitator superfamily - - - - - - - - - - - - Acyltransferase,MFS_1 k141_3875_4 1116375.VEJY3_17431 2.32e-136 387.0 COG1075@1|root,COG1075@2|Bacteria,1N2W0@1224|Proteobacteria,1SAMR@1236|Gammaproteobacteria,1XVQX@135623|Vibrionales 135623|Vibrionales S acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - - - - - - - - - - PGAP1 k141_3875_5 1116375.VEJY3_17426 7.17e-151 424.0 COG0108@1|root,COG0108@2|Bacteria,1MU8P@1224|Proteobacteria,1RQ49@1236|Gammaproteobacteria,1XT0Y@135623|Vibrionales 135623|Vibrionales H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate ribB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.12 ko:K02858 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R07281 RC01792,RC01815 ko00000,ko00001,ko00002,ko01000 - - - DHBP_synthase k141_3875_6 1116375.VEJY3_17421 1.47e-109 317.0 COG0386@1|root,COG0386@2|Bacteria,1RDR8@1224|Proteobacteria,1S3WV@1236|Gammaproteobacteria,1XVIT@135623|Vibrionales 135623|Vibrionales O Belongs to the glutathione peroxidase family - - 1.11.1.9 ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 - R00274,R07034,R07035 RC00011,RC00982 ko00000,ko00001,ko01000 - - - GSHPx k141_3875_7 1116375.VEJY3_17416 5.29e-87 257.0 2DR7N@1|root,33AJV@2|Bacteria,1NGUY@1224|Proteobacteria,1SGQC@1236|Gammaproteobacteria,1XYUJ@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF3429) VPA1252 - - - - - - - - - - - DUF3429 k141_3875_8 1116375.VEJY3_17401 2.39e-60 186.0 COG0296@1|root,COG0296@2|Bacteria,1N8WX@1224|Proteobacteria,1S8R5@1236|Gammaproteobacteria,1Y291@135623|Vibrionales 135623|Vibrionales G Belongs to the glycosyl hydrolase 13 family - - - - - - - - - - - - AMPK1_CBM k141_3875_9 1116375.VEJY3_17396 1.5e-53 170.0 COG0818@1|root,COG0818@2|Bacteria,1MZ3Q@1224|Proteobacteria,1S92I@1236|Gammaproteobacteria,1XXSV@135623|Vibrionales 135623|Vibrionales M Recycling of diacylglycerol produced during the turnover of membrane phospholipid - - 2.7.1.107 ko:K00901 ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231 - R02240 RC00002,RC00017 ko00000,ko00001,ko01000 - - - DAGK_prokar k141_3875_10 1116375.VEJY3_17391 0.0 951.0 COG2194@1|root,COG2194@2|Bacteria,1MWS7@1224|Proteobacteria,1RMNG@1236|Gammaproteobacteria,1XSQM@135623|Vibrionales 135623|Vibrionales S membrane-associated, metal-dependent hydrolase eptA - 2.7.8.43 ko:K03760 ko01503,map01503 M00722 R11555,R11556,R11557 RC00002 ko00000,ko00001,ko00002,ko01000,ko01005 - - - DUF1705,Sulfatase k141_3875_11 1116375.VEJY3_17386 1.92e-194 542.0 COG0673@1|root,COG0673@2|Bacteria,1MVCX@1224|Proteobacteria,1RP1P@1236|Gammaproteobacteria,1XU9E@135623|Vibrionales 135623|Vibrionales S Oxidoreductase family, NAD-binding Rossmann fold VVA1152 - - ko:K03810 - - - - ko00000 - - - GFO_IDH_MocA k141_364_1 29495.EA26_20065 1.26e-22 95.9 COG0471@1|root,COG0471@2|Bacteria,1R6QF@1224|Proteobacteria,1RQIG@1236|Gammaproteobacteria,1XTZX@135623|Vibrionales 135623|Vibrionales P COG0471 Di- and tricarboxylate transporters - - - ko:K14445 - - - - ko00000,ko02000 2.A.47.1 - - Na_sulph_symp k141_15756_2 1042377.AFPJ01000019_gene2481 8.45e-36 121.0 COG0291@1|root,COG0291@2|Bacteria,1N6V4@1224|Proteobacteria,1SCHI@1236|Gammaproteobacteria,468CG@72275|Alteromonadaceae 1236|Gammaproteobacteria J Belongs to the bacterial ribosomal protein bL35 family rpmI GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02916 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L35p k141_15756_4 1453501.JELR01000001_gene2069 8.77e-05 43.9 COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,1RN22@1236|Gammaproteobacteria,465BM@72275|Alteromonadaceae 1236|Gammaproteobacteria J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily pheS GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 ko:K01889 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iJN746.PP_2469 Phe_tRNA-synt_N,tRNA-synt_2d k141_20421_1 1294265.JCM21738_5521 8.87e-69 209.0 COG2832@1|root,COG2832@2|Bacteria,1V6I1@1239|Firmicutes 1239|Firmicutes S Protein of unknown function (DUF454) - - - ko:K09790 - - - - ko00000 - - - DUF454 k141_20421_2 1231057.AMGD01000030_gene1789 1.46e-22 91.7 COG0400@1|root,COG0400@2|Bacteria,1TPBY@1239|Firmicutes,4HB45@91061|Bacilli,26EXH@186818|Planococcaceae 91061|Bacilli S Carboxylesterase yahD - - ko:K06999 - - - - ko00000 - - - Abhydrolase_2,DLH k141_26587_1 218284.CCDN010000001_gene1793 2.69e-28 105.0 COG1388@1|root,COG1388@2|Bacteria 2|Bacteria M LysM domain yneA GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 - ko:K06194 - - - - ko00000 1.A.34.1.2 - - LysM,OapA,Peptidase_M23 k141_26587_2 218284.CCDN010000001_gene1792 3.43e-128 367.0 COG1961@1|root,COG1961@2|Bacteria,1TR74@1239|Firmicutes,4HBJI@91061|Bacilli,1ZCET@1386|Bacillus 91061|Bacilli L resolvase yneB GO:0000150,GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140097,GO:1901360 - - - - - - - - - - Resolvase k141_26587_3 218284.CCDN010000001_gene1791 2.06e-34 119.0 COG4224@1|root,COG4224@2|Bacteria,1VEKJ@1239|Firmicutes,4HNIB@91061|Bacilli,1ZIU8@1386|Bacillus 91061|Bacilli S UPF0291 protein ynzC - - - - - - - - - - - DUF896 k141_10966_2 218284.CCDN010000001_gene637 3.04e-126 370.0 COG0536@1|root,COG0536@2|Bacteria,1TPX7@1239|Firmicutes,4H9P8@91061|Bacilli,1ZCM4@1386|Bacillus 91061|Bacilli S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control obg GO:0000003,GO:0000160,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0017076,GO:0019001,GO:0019954,GO:0023052,GO:0030436,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035556,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043934,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03979 - - - - ko00000,ko01000,ko03009 - - - DUF1967,GTP1_OBG,MMR_HSR1 k141_19287_1 1517416.IDAT_03755 9e-34 121.0 COG1846@1|root,COG1846@2|Bacteria,1RFUJ@1224|Proteobacteria,1S8JQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator - - - - - - - - - - - - MarR,MarR_2 k141_12252_2 1279017.AQYJ01000022_gene2596 1.75e-48 158.0 2E5XZ@1|root,330MS@2|Bacteria,1NBN8@1224|Proteobacteria,1SCZT@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_31228_2 1294265.JCM21738_3738 2.22e-178 496.0 COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,4H9S9@91061|Bacilli,1ZBQI@1386|Bacillus 91061|Bacilli E Methionine aminopeptidase map - 3.4.11.18 ko:K01265 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M24 k141_31228_3 935837.JAEK01000024_gene1045 1.15e-05 46.2 COG0563@1|root,COG0563@2|Bacteria,1TP27@1239|Firmicutes,4HA89@91061|Bacilli,1ZBYM@1386|Bacillus 91061|Bacilli F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism adk GO:0003674,GO:0003824,GO:0004017,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ADK,ADK_lid k141_3903_1 1173023.KE650771_gene3154 4.88e-16 79.3 COG2091@1|root,COG2091@2|Bacteria,1G5GA@1117|Cyanobacteria,1JH83@1189|Stigonemataceae 1117|Cyanobacteria H 4'-phosphopantetheinyl transferase superfamily hetI GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008897,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016780,GO:0019752,GO:0019878,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - ko:K06133 ko00770,map00770 - R01625 RC00002 ko00000,ko00001,ko01000 - - - ACPS k141_2686_1 1453501.JELR01000002_gene1147 1.73e-164 465.0 COG1294@1|root,COG1294@2|Bacteria,1MURP@1224|Proteobacteria,1RN0N@1236|Gammaproteobacteria,4663H@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1294 Cytochrome bd-type quinol oxidase, subunit 2 cydB - 1.10.3.14 ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - Cyt_bd_oxida_II k141_24026_1 218284.CCDN010000001_gene1199 2.81e-114 330.0 COG1272@1|root,COG1272@2|Bacteria,1TSFK@1239|Firmicutes,4HAT2@91061|Bacilli,1ZBJJ@1386|Bacillus 91061|Bacilli S protein, Hemolysin III yplQ - - ko:K11068 - - - - ko00000,ko02042 - - - HlyIII k141_24026_2 218284.CCDN010000001_gene1200 4.48e-05 45.8 COG2135@1|root,COG2135@2|Bacteria,1TRRV@1239|Firmicutes,4HDUN@91061|Bacilli,1ZCQB@1386|Bacillus 91061|Bacilli S Belongs to the SOS response-associated peptidase family yoqW - - - - - - - - - - - SRAP k141_10967_1 42565.FP66_08690 7.19e-120 353.0 COG0733@1|root,COG0733@2|Bacteria,1MUZJ@1224|Proteobacteria,1RPCT@1236|Gammaproteobacteria,1XN22@135619|Oceanospirillales 135619|Oceanospirillales S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family - - - ko:K03308 - - - - ko00000 2.A.22.4,2.A.22.5 - - SNF k141_33546_1 1279017.AQYJ01000026_gene24 1.06e-118 343.0 COG1187@1|root,COG1187@2|Bacteria,1MU6M@1224|Proteobacteria,1RQA9@1236|Gammaproteobacteria,46734@72275|Alteromonadaceae 1236|Gammaproteobacteria J Belongs to the pseudouridine synthase RsuA family rsuA GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19 ko:K06183 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 k141_33546_2 1279017.AQYJ01000026_gene25 3.73e-89 272.0 COG2813@1|root,COG2813@2|Bacteria,1MXE9@1224|Proteobacteria,1RQCH@1236|Gammaproteobacteria,466JK@72275|Alteromonadaceae 1236|Gammaproteobacteria J Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle rsmC GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052914,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.172 ko:K00564 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - MTS,MTS_N k141_26588_1 218284.CCDN010000002_gene2255 1.49e-152 447.0 COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,4H9SP@91061|Bacilli,1ZAPS@1386|Bacillus 91061|Bacilli P COG2217 Cation transport ATPase zosA - 3.6.3.3,3.6.3.5 ko:K01534 - - - - ko00000,ko01000 3.A.3.6 - - E1-E2_ATPase,Hydrolase k141_8612_2 218284.CCDN010000001_gene606 6.46e-48 165.0 COG1388@1|root,COG1388@2|Bacteria,1U052@1239|Firmicutes,4HF2C@91061|Bacilli,1ZB2H@1386|Bacillus 91061|Bacilli M stage VI sporulation protein D spoVID GO:0003674,GO:0005488,GO:0005515,GO:0019899,GO:0051117 - ko:K06417 - - - - ko00000 - - - LysM k141_32289_1 1116375.VEJY3_19421 4.43e-152 437.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,1RXSY@1236|Gammaproteobacteria,1XZX7@135623|Vibrionales 135623|Vibrionales G COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - - - - - - - - - - DctM k141_5018_1 318167.Sfri_0612 2.86e-69 215.0 COG3128@1|root,COG3128@2|Bacteria,1MUI7@1224|Proteobacteria,1RQ0M@1236|Gammaproteobacteria,2Q9DD@267890|Shewanellaceae 1236|Gammaproteobacteria C PKHD-type hydroxylase ybiX GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0033554,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0098771 - ko:K07336 - - - - ko00000,ko01000 - - - 2OG-FeII_Oxy_3 k141_5018_2 715451.ambt_19550 2.08e-50 177.0 COG4774@1|root,COG4774@2|Bacteria,1MV0X@1224|Proteobacteria,1RN3C@1236|Gammaproteobacteria,464QQ@72275|Alteromonadaceae 1236|Gammaproteobacteria P TonB dependent receptor - - - ko:K16090 - - - - ko00000,ko02000 1.B.14.1.11 - - Plug,TonB_dep_Rec k141_13408_1 223926.28805024 1.41e-91 268.0 COG3245@1|root,COG3245@2|Bacteria,1MZBZ@1224|Proteobacteria,1S9Z9@1236|Gammaproteobacteria,1XX0W@135623|Vibrionales 135623|Vibrionales C cytochrome c5 cycB - - - - - - - - - - - Cytochrome_CBB3 k141_13408_2 674977.VMC_10970 0.0 1280.0 COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,1RNJI@1236|Gammaproteobacteria,1XTFN@135623|Vibrionales 135623|Vibrionales L it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction rep - 3.6.4.12 ko:K03656 - - - - ko00000,ko01000,ko03400 - - - UvrD-helicase,UvrD_C k141_13408_3 223926.28805022 2.23e-103 302.0 COG1309@1|root,COG1309@2|Bacteria,1N0GT@1224|Proteobacteria,1SA00@1236|Gammaproteobacteria,1XVJ8@135623|Vibrionales 135623|Vibrionales K Transcriptional regulator - - - ko:K18136 ko01501,map01501 - - - ko00000,ko00001,ko03000 - - - TetR_C_10,TetR_N k141_13408_4 1116375.VEJY3_00180 1.39e-239 661.0 COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,1RQJ9@1236|Gammaproteobacteria,1XT7F@135623|Vibrionales 135623|Vibrionales M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K03585 ko01501,ko01503,map01501,map01503 M00646,M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,8.A.1.6 - - HlyD_D23 k141_13408_5 1116375.VEJY3_00175 6.05e-221 638.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1XSSQ@135623|Vibrionales 135623|Vibrionales V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K18138 ko01501,ko01503,map01501,map01503 M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2 - - ACR_tran k141_8613_1 218284.CCDN010000001_gene1330 1.56e-101 319.0 COG0567@1|root,COG0567@2|Bacteria,1TRDW@1239|Firmicutes,4HAUI@91061|Bacilli,1ZAX3@1386|Bacillus 91061|Bacilli C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) odhA GO:0003674,GO:0003824,GO:0004591,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016624,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045333,GO:0055114,GO:0071704,GO:0072350,GO:1902494,GO:1990204,GO:1990234 1.2.4.2 ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R00621,R01933,R01940,R03316,R08549 RC00004,RC00027,RC00627,RC02743,RC02833,RC02883 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr k141_10968_1 218284.CCDN010000004_gene3081 6.01e-96 284.0 COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,4HARE@91061|Bacilli,1ZC55@1386|Bacillus 91061|Bacilli S reductase yvgN - - - - - - - - - - - Aldo_ket_red k141_20423_2 1279017.AQYJ01000020_gene1318 2.57e-91 283.0 COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,1RNV5@1236|Gammaproteobacteria,464FJ@72275|Alteromonadaceae 1236|Gammaproteobacteria I Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) liuB - 6.4.1.4 ko:K01969 ko00280,ko01100,map00280,map01100 M00036 R04138 RC00367,RC00942 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans k141_12254_1 1453501.JELR01000002_gene607 3.07e-16 75.9 COG3150@1|root,COG3150@2|Bacteria,1MVJF@1224|Proteobacteria,1S5WF@1236|Gammaproteobacteria,4674V@72275|Alteromonadaceae 1236|Gammaproteobacteria S esterase yqiA GO:0003674,GO:0003824,GO:0016787,GO:0016788 - ko:K07000 - - - - ko00000 - - - UPF0227 k141_6346_1 218284.CCDN010000002_gene2892 1.27e-137 397.0 COG0492@1|root,COG0492@2|Bacteria,1TRPN@1239|Firmicutes,4HACJ@91061|Bacilli,1ZB05@1386|Bacillus 91061|Bacilli C Ferredoxin--NADP reductase - - 1.18.1.2,1.19.1.1 ko:K21567 - - - - ko00000,ko01000 - - - Pyr_redox_2,Pyr_redox_3 k141_31229_1 1449063.JMLS01000001_gene4580 6.42e-33 131.0 COG1132@1|root,COG1132@2|Bacteria,1UZA0@1239|Firmicutes,4HC2E@91061|Bacilli,26VPZ@186822|Paenibacillaceae 91061|Bacilli V ABC transporter transmembrane region - - - - - - - - - - - - ABC_membrane,ABC_tran k141_12586_2 1453501.JELR01000001_gene2939 1.2e-35 127.0 COG0500@1|root,COG2226@2|Bacteria,1MXDY@1224|Proteobacteria,1RMU7@1236|Gammaproteobacteria,466NC@72275|Alteromonadaceae 1236|Gammaproteobacteria Q COG0500 SAM-dependent methyltransferases rrmA GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008270,GO:0008649,GO:0008757,GO:0008989,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.187 ko:K00563 - - R07233 RC00003 ko00000,ko01000,ko03009 - - - Methyltransf_11,Methyltransf_25,Methyltransf_31 k141_7588_1 345341.KUTG_06912 4.75e-22 89.4 COG3832@1|root,COG3832@2|Bacteria,2IN0A@201174|Actinobacteria,4E57U@85010|Pseudonocardiales 201174|Actinobacteria S Polyketide cyclase / dehydrase and lipid transport - - - - - - - - - - - - Polyketide_cyc2 k141_7588_2 1169144.KB910954_gene22 7.21e-11 60.8 COG1187@1|root,COG1187@2|Bacteria,1TP68@1239|Firmicutes,4HAVS@91061|Bacilli,1ZC7N@1386|Bacillus 91061|Bacilli J Belongs to the pseudouridine synthase RsuA family rluF - 5.4.99.21 ko:K06182 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 k141_26893_1 218284.CCDN010000001_gene605 1.34e-149 430.0 COG0001@1|root,COG0001@2|Bacteria,1TPNH@1239|Firmicutes,4HANQ@91061|Bacilli,1ZBUT@1386|Bacillus 91061|Bacilli H Glutamate-1-semialdehyde aminotransferase hemL - 5.4.3.8 ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02272 RC00677 ko00000,ko00001,ko00002,ko01000,ko01007 - - iSB619.SA_RS08395 Aminotran_3 k141_30118_1 1502851.FG93_06077 1.84e-30 120.0 COG0760@1|root,COG0760@2|Bacteria,1R4ZR@1224|Proteobacteria,2U874@28211|Alphaproteobacteria,3JRK1@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O PPIC-type PPIASE domain - - 5.2.1.8 ko:K03769 - - - - ko00000,ko01000,ko03110 - - - Rotamase_2 k141_30118_2 1042377.AFPJ01000011_gene427 1.44e-132 388.0 COG2370@1|root,COG2370@2|Bacteria,1MV6Z@1224|Proteobacteria,1RRHA@1236|Gammaproteobacteria,468HI@72275|Alteromonadaceae 1236|Gammaproteobacteria O HupE / UreJ protein - - - - - - - - - - - - HupE_UreJ_2 k141_6506_1 218284.CCDN010000011_gene4403 2.77e-35 128.0 COG0533@1|root,COG0533@2|Bacteria,1TQDR@1239|Firmicutes,4HANB@91061|Bacilli,1ZBT3@1386|Bacillus 91061|Bacilli O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction tsaD GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 ko:K01409 - - R10648 RC00070,RC00416 ko00000,ko01000,ko03016 - - - Peptidase_M22 k141_32483_1 218284.CCDN010000007_gene3936 3.32e-118 344.0 COG0280@1|root,COG0280@2|Bacteria,1TPQ0@1239|Firmicutes,4H9VH@91061|Bacilli,1ZC98@1386|Bacillus 91061|Bacilli C In Salmonella this enzyme is required for ethanolamine catabolism pta - 2.3.1.8,3.6.3.21 ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00236,M00357,M00579 R00230,R00921 RC00004,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3 - iSB619.SA_RS03155 PTA_PTB k141_2846_1 1340434.AXVA01000013_gene444 1.63e-105 318.0 COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,4HC50@91061|Bacilli,1ZQ98@1386|Bacillus 91061|Bacilli I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) yqjD GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016421,GO:0016874,GO:0016885,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0071704,GO:0072329,GO:1901575 2.1.3.15,6.4.1.3 ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 M00373,M00741 R01859 RC00097,RC00609 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans k141_5345_1 1294265.JCM21738_4165 1.57e-276 788.0 COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,4HA24@91061|Bacilli,1ZDK0@1386|Bacillus 91061|Bacilli K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoC GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 k141_20685_1 218284.CCDN010000005_gene3492 2.82e-99 307.0 COG1368@1|root,COG1368@2|Bacteria,1TRMA@1239|Firmicutes,4H9S0@91061|Bacilli,1ZBBV@1386|Bacillus 91061|Bacilli M Belongs to the LTA synthase family yfnI GO:0005575,GO:0005576 2.7.8.20 ko:K19005 ko00561,ko01100,map00561,map01100 - R05081,R10849 RC00017 ko00000,ko00001,ko01000 - - - Sulfatase k141_4151_1 1090319.KE386571_gene3222 3.62e-24 106.0 COG1749@1|root,COG1749@2|Bacteria,1MU5J@1224|Proteobacteria,2UNQI@28211|Alphaproteobacteria,2K2SG@204457|Sphingomonadales 204457|Sphingomonadales N Flagellar basal body rod FlgEFG protein C-terminal - - - ko:K02390 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FlaE,Flg_bb_rod,Flg_bbr_C k141_13748_1 218284.CCDN010000001_gene1929 1.31e-167 478.0 COG1157@1|root,COG1157@2|Bacteria,1TP0R@1239|Firmicutes,4HAUY@91061|Bacilli,1ZBXU@1386|Bacillus 91061|Bacilli NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase fliI - 3.6.3.14 ko:K02412 ko02040,map02040 - - - ko00000,ko00001,ko01000,ko02035,ko02044 3.A.6.2,3.A.6.3 - - ATP-synt_ab,ATP-synt_ab_N k141_36068_1 1206741.BAFX01000014_gene7011 1.22e-06 52.8 COG2207@1|root,COG2207@2|Bacteria,2GM4P@201174|Actinobacteria,4FXCG@85025|Nocardiaceae 201174|Actinobacteria K Arabinose-binding domain of AraC transcription regulator, N-term - - - - - - - - - - - - Arabinose_bd,HTH_18 k141_36068_2 675812.VHA_002637 5.22e-38 136.0 COG3047@1|root,COG3047@2|Bacteria,1RJMG@1224|Proteobacteria,1SQWX@1236|Gammaproteobacteria 1236|Gammaproteobacteria M OmpW family - - - ko:K07275 - - - - ko00000 - - - - k141_23227_2 218284.CCDN010000001_gene1253 2.03e-45 151.0 COG0586@1|root,COG0586@2|Bacteria,1V1D4@1239|Firmicutes,4HFSU@91061|Bacilli,1ZCPB@1386|Bacillus 91061|Bacilli S membrane-associated protein yngC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - SNARE_assoc k141_24254_1 1294265.JCM21738_3398 9.68e-138 400.0 COG0168@1|root,COG0168@2|Bacteria,1TQ4S@1239|Firmicutes,4H9ME@91061|Bacilli,1ZD2H@1386|Bacillus 91061|Bacilli P COG0168 Trk-type K transport systems, membrane components ktrD - - - - - - - - - - - TrkH k141_20686_1 1168289.AJKI01000031_gene931 7.85e-109 343.0 COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes 976|Bacteroidetes V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran k141_32484_1 1385514.N782_00745 5.85e-24 95.1 2F8MN@1|root,34105@2|Bacteria,1VY9K@1239|Firmicutes,4HWX2@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - k141_19567_1 1340434.AXVA01000017_gene4125 1.76e-98 305.0 COG1001@1|root,COG1001@2|Bacteria,1TP84@1239|Firmicutes,4HBB2@91061|Bacilli,1ZCHI@1386|Bacillus 91061|Bacilli F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family ade GO:0003674,GO:0003824,GO:0006040,GO:0006044,GO:0006046,GO:0008150,GO:0008152,GO:0008448,GO:0009056,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0046348,GO:0071704,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901575 3.5.4.2 ko:K01486 ko00230,ko01100,map00230,map01100 - R01244 RC00477 ko00000,ko00001,ko01000 - - iYO844.BSU14520 Adenine_deam_C,Amidohydro_1 k141_2847_1 1461580.CCAS010000002_gene344 5.3e-09 57.4 COG0755@1|root,COG0755@2|Bacteria,1V4A6@1239|Firmicutes,4HHG4@91061|Bacilli,1ZDZJ@1386|Bacillus 91061|Bacilli O COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component - - - ko:K02195 ko02010,map02010 M00259 - - ko00000,ko00001,ko00002,ko02000 3.A.1.107 - - Cytochrom_C_asm k141_2847_2 1294265.JCM21738_2223 5.37e-40 139.0 COG2386@1|root,COG2386@2|Bacteria,1VDEP@1239|Firmicutes,4HMK3@91061|Bacilli,1ZEI4@1386|Bacillus 91061|Bacilli O COG2386 ABC-type transport system involved in cytochrome c biogenesis, permease component - - - ko:K02194 ko02010,map02010 M00259 - - ko00000,ko00001,ko00002,ko02000 3.A.1.107 - - CcmB k141_29016_1 1121937.AUHJ01000020_gene1276 8.18e-144 423.0 COG0477@1|root,COG2814@2|Bacteria,1MU1I@1224|Proteobacteria,1RNTG@1236|Gammaproteobacteria,4672P@72275|Alteromonadaceae 1236|Gammaproteobacteria U Major facilitator superfamily emrB - - ko:K03446 - M00701 - - ko00000,ko00002,ko02000 2.A.1.3 - - MFS_1 k141_29016_2 1279017.AQYJ01000028_gene2331 8.59e-75 226.0 COG4731@1|root,COG4731@2|Bacteria,1N19Y@1224|Proteobacteria,1SC9D@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Uncharacterized protein conserved in bacteria (DUF2147) - - - - - - - - - - - - DUF2147 k141_29016_3 1279017.AQYJ01000028_gene2332 3.25e-162 468.0 COG0397@1|root,COG0397@2|Bacteria,1MVK3@1224|Proteobacteria,1RNCS@1236|Gammaproteobacteria,4646G@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the UPF0061 (SELO) family ydiU - - ko:K08997 - - - - ko00000 - - - UPF0061 k141_18439_1 1453501.JELR01000002_gene931 7.69e-44 146.0 COG0802@1|root,COG0802@2|Bacteria,1RGYU@1224|Proteobacteria,1S6IB@1236|Gammaproteobacteria,467AG@72275|Alteromonadaceae 1236|Gammaproteobacteria S ATPase or kinase yjeE GO:0000166,GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043531,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 - ko:K06925 - - - - ko00000,ko03016 - - - TsaE k141_24255_2 218284.CCDN010000001_gene16 1.15e-145 413.0 COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,4HBFV@91061|Bacilli,1ZD4X@1386|Bacillus 91061|Bacilli J Belongs to the RNA methyltransferase TrmD family trmD GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 ko:K00554 - - R00597 RC00003,RC00334 ko00000,ko01000,ko03016 - - - tRNA_m1G_MT k141_11289_1 1453501.JELR01000001_gene1856 6e-44 147.0 COG0526@1|root,COG0526@2|Bacteria,1N726@1224|Proteobacteria,1SD4C@1236|Gammaproteobacteria,468P8@72275|Alteromonadaceae 1236|Gammaproteobacteria CO COG0526 Thiol-disulfide isomerase and thioredoxins resA - - - - - - - - - - - AhpC-TSA k141_11289_2 1042377.AFPJ01000037_gene2977 7.33e-62 207.0 COG1295@1|root,COG1295@2|Bacteria,1QICW@1224|Proteobacteria,1RMKI@1236|Gammaproteobacteria,4669T@72275|Alteromonadaceae 1236|Gammaproteobacteria S membrane rbn GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K07058 - - - - ko00000 - - - Virul_fac_BrkB k141_18440_1 1347086.CCBA010000027_gene3587 2.47e-10 62.0 COG0635@1|root,COG0635@2|Bacteria,1TREM@1239|Firmicutes,4HC2D@91061|Bacilli,1ZCRB@1386|Bacillus 91061|Bacilli H coproporphyrinogen III oxidase hemZ - - - - - - - - - - - Radical_SAM k141_15958_2 1384054.N790_01700 1.23e-56 184.0 COG1670@1|root,COG1670@2|Bacteria,1N619@1224|Proteobacteria,1S2TR@1236|Gammaproteobacteria,1XCMN@135614|Xanthomonadales 135614|Xanthomonadales J Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_3 k141_5374_1 1294265.JCM21738_293 2.8e-47 153.0 COG1815@1|root,COG1815@2|Bacteria,1VEUZ@1239|Firmicutes,4HPTR@91061|Bacilli,1ZQN1@1386|Bacillus 91061|Bacilli N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body flgB - - ko:K02387 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod k141_5374_2 1294265.JCM21738_294 1.09e-72 219.0 COG1558@1|root,COG1558@2|Bacteria,1V6NB@1239|Firmicutes,4HH4W@91061|Bacilli,1ZGA0@1386|Bacillus 91061|Bacilli N Belongs to the flagella basal body rod proteins family flgC GO:0001539,GO:0005575,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009424,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588 - ko:K02388 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C k141_12612_1 1453501.JELR01000002_gene1539 1.2e-05 47.0 COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,1RM7S@1236|Gammaproteobacteria,4640S@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0739 Membrane proteins related to metalloendopeptidases yebA - - - - - - - - - - - OapA,OapA_N,Peptidase_M23 k141_2862_1 997296.PB1_15634 1.76e-95 295.0 COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,4HAB7@91061|Bacilli,1ZDHC@1386|Bacillus 91061|Bacilli S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid spoVB - - ko:K06409 - - - - ko00000,ko02000 2.A.66.2.14 - - Polysacc_synt,Polysacc_synt_C k141_18468_1 218284.CCDN010000008_gene4186 4.79e-64 201.0 COG0607@1|root,COG0607@2|Bacteria,1VES3@1239|Firmicutes,4HNRE@91061|Bacilli,1ZH5X@1386|Bacillus 91061|Bacilli P Sulfurtransferase ytwF - - - - - - - - - - - Rhodanese k141_6520_1 1379698.RBG1_1C00001G0907 1.67e-42 149.0 COG1024@1|root,COG1024@2|Bacteria 2|Bacteria I Enoyl-CoA hydratase bamA GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009150,GO:0009154,GO:0009166,GO:0009259,GO:0009261,GO:0009987,GO:0016787,GO:0016822,GO:0016823,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0033865,GO:0033869,GO:0033875,GO:0034031,GO:0034032,GO:0034034,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044273,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901787,GO:1901788 3.7.1.21 ko:K07539,ko:K18570 ko00332,ko00362,ko01100,ko01120,ko01130,ko01220,map00332,map00362,map01100,map01120,map01130,map01220 M00541 R05593,R05594,R10696,R10750 RC01430,RC01431,RC03237,RC03270 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 k141_6520_2 1125971.ASJB01000042_gene3459 4.36e-07 53.5 COG1028@1|root,COG3347@1|root,COG1028@2|Bacteria,COG3347@2|Bacteria,2GNEI@201174|Actinobacteria,4DX5Z@85010|Pseudonocardiales 201174|Actinobacteria IQ Class II Aldolase and Adducin N-terminal domain srlD - 1.1.1.140 ko:K00068 ko00051,map00051 - R05607 RC00085 ko00000,ko00001,ko01000 - - - Aldolase_II,adh_short,adh_short_C2 k141_23246_1 1294265.JCM21738_2987 5.07e-114 335.0 COG1165@1|root,COG1165@2|Bacteria,1TRDB@1239|Firmicutes,4HC48@91061|Bacilli,1ZANU@1386|Bacillus 91061|Bacilli H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) menD - 2.2.1.9 ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R08165 RC02186 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS05085 TPP_enzyme_C,TPP_enzyme_M_2,TPP_enzyme_N k141_10161_2 435908.IDSA_08885 2.52e-44 164.0 COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,1RMT7@1236|Gammaproteobacteria,2QEYF@267893|Idiomarinaceae 1236|Gammaproteobacteria S Bacterial protein of unknown function (DUF885) - - - - - - - - - - - - DUF885 k141_19591_1 218284.CCDN010000001_gene1391 1.64e-33 123.0 COG4814@1|root,COG4814@2|Bacteria,1V910@1239|Firmicutes,4HF90@91061|Bacilli,1ZHBI@1386|Bacillus 91061|Bacilli S Alpha/beta hydrolase of unknown function (DUF915) - - - - - - - - - - - - DUF915 k141_680_1 1453501.JELR01000001_gene2655 1.11e-149 437.0 COG2234@1|root,COG2234@2|Bacteria,1MV86@1224|Proteobacteria,1RNNQ@1236|Gammaproteobacteria,464MC@72275|Alteromonadaceae 1236|Gammaproteobacteria S Peptidase family M28 - - - - - - - - - - - - PA,Peptidase_M28 k141_17136_2 1121090.KB894685_gene3537 1.63e-47 171.0 COG2866@1|root,COG2866@2|Bacteria,1TSF6@1239|Firmicutes,4HDT5@91061|Bacilli,1ZBGR@1386|Bacillus 91061|Bacilli E Zinc carboxypeptidase - - - - - - - - - - - - Peptidase_M14 k141_23247_1 218284.CCDN010000001_gene745 8.76e-21 85.9 29RH9@1|root,30CK6@2|Bacteria,1UA17@1239|Firmicutes,4IK9T@91061|Bacilli,1ZG2T@1386|Bacillus 91061|Bacilli - - yqfB - - - - - - - - - - - - k141_23247_2 218284.CCDN010000001_gene746 5.55e-56 175.0 2E4EZ@1|root,32ZA5@2|Bacteria,1VF5C@1239|Firmicutes,4HNQG@91061|Bacilli,1ZHZA@1386|Bacillus 91061|Bacilli S sporulation protein YqfC yqfC - - - - - - - - - - - YabP k141_12613_1 218284.CCDN010000001_gene1330 7.51e-116 358.0 COG0567@1|root,COG0567@2|Bacteria,1TRDW@1239|Firmicutes,4HAUI@91061|Bacilli,1ZAX3@1386|Bacillus 91061|Bacilli C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) odhA GO:0003674,GO:0003824,GO:0004591,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016624,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045333,GO:0055114,GO:0071704,GO:0072350,GO:1902494,GO:1990204,GO:1990234 1.2.4.2 ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R00621,R01933,R01940,R03316,R08549 RC00004,RC00027,RC00627,RC02743,RC02833,RC02883 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr k141_18469_1 218284.CCDN010000002_gene2735 1.56e-86 258.0 COG1813@1|root,COG1917@1|root,COG1813@2|Bacteria,COG1917@2|Bacteria,1UIX1@1239|Firmicutes,4ISV8@91061|Bacilli,1ZS6X@1386|Bacillus 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - Cupin_2,HTH_3 k141_681_1 1460634.JCM19037_1601 1.84e-59 189.0 COG1875@1|root,COG1875@2|Bacteria,1V4CX@1239|Firmicutes 1239|Firmicutes T PhoH-like protein - - - ko:K07175 - - - - ko00000 - - - PhoH k141_13782_1 218284.CCDN010000007_gene3904 5.43e-101 302.0 COG1168@1|root,COG1168@2|Bacteria,1TP5G@1239|Firmicutes,4H9PE@91061|Bacilli,1ZCQC@1386|Bacillus 91061|Bacilli E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities patB - 4.4.1.8 ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 - R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 k141_8934_1 1294265.JCM21738_4843 5.03e-21 90.5 COG4863@1|root,COG4863@2|Bacteria,1UV48@1239|Firmicutes,4HF30@91061|Bacilli,1ZD30@1386|Bacillus 91061|Bacilli S protein conserved in bacteria yycH - - - - - - - - - - - YycH k141_8934_2 1294265.JCM21738_4844 9.83e-92 273.0 COG4853@1|root,COG4853@2|Bacteria,1V1FW@1239|Firmicutes,4HFWZ@91061|Bacilli,1ZDGV@1386|Bacillus 91061|Bacilli S protein conserved in bacteria yycI - - - - - - - - - - - YycI k141_25616_1 218284.CCDN010000006_gene3517 7.73e-49 171.0 COG3263@1|root,COG3263@2|Bacteria,1TQPJ@1239|Firmicutes,4HC8I@91061|Bacilli,1ZC6H@1386|Bacillus 91061|Bacilli P COG3263 NhaP-type Na H and K H antiporters with a unique C-terminal domain cvrA - - ko:K11105 - - - - ko00000,ko02000 2.A.36.6 - - Na_H_Exchanger,TrkA_C k141_18470_1 1161401.ASJA01000005_gene2417 1.05e-80 264.0 COG1629@1|root,COG4771@2|Bacteria,1MVFB@1224|Proteobacteria,2U2UJ@28211|Alphaproteobacteria,43WVS@69657|Hyphomonadaceae 28211|Alphaproteobacteria P receptor - - - - - - - - - - - - Plug,TonB_dep_Rec k141_23248_1 218284.CCDN010000009_gene4275 7.88e-107 320.0 COG4856@1|root,COG4856@2|Bacteria,1TSIV@1239|Firmicutes,4HD8Y@91061|Bacilli,1ZB2T@1386|Bacillus 91061|Bacilli S protein conserved in bacteria ybbR GO:0008150,GO:0031279,GO:0031281,GO:0043085,GO:0044093,GO:0045761,GO:0045762,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009 - - - - - - - - - - YbbR k141_2863_1 1121930.AQXG01000011_gene1722 1.31e-146 426.0 COG5276@1|root,COG5276@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - LVIVD k141_32502_2 1034347.CAHJ01000021_gene3364 2.59e-51 174.0 COG0477@1|root,COG2814@2|Bacteria,1U72T@1239|Firmicutes,4HCHH@91061|Bacilli,1ZCHP@1386|Bacillus 91061|Bacilli EGP COG0477 Permeases of the major facilitator superfamily ykuC - - - - - - - - - - - MFS_1 k141_682_1 232721.Ajs_1946 1.36e-14 79.0 COG2207@1|root,COG2207@2|Bacteria,1RG67@1224|Proteobacteria,2VZ24@28216|Betaproteobacteria 28216|Betaproteobacteria K transcriptional regulator, AraC family - - - - - - - - - - - - HTH_18 k141_5376_1 1279017.AQYJ01000026_gene279 4.5e-17 78.2 COG0571@1|root,COG0571@2|Bacteria,1MUQ6@1224|Proteobacteria,1RN0C@1236|Gammaproteobacteria,466PY@72275|Alteromonadaceae 1236|Gammaproteobacteria J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism rnc GO:0000287,GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019899,GO:0022613,GO:0032296,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 ko:K03685 ko03008,ko05205,map03008,map05205 - - - ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 - - - Ribonucleas_3_3,dsrm k141_35045_1 1294265.JCM21738_1650 3.71e-113 328.0 COG0106@1|root,COG0106@2|Bacteria,1V1IR@1239|Firmicutes,4HACP@91061|Bacilli,1ZC7D@1386|Bacillus 91061|Bacilli E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase hisA GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04640 RC00945 ko00000,ko00001,ko00002,ko01000 - - - His_biosynth k141_29037_1 997296.PB1_06887 5.56e-22 94.4 COG0760@1|root,COG0760@2|Bacteria,1UZZM@1239|Firmicutes,4HE14@91061|Bacilli,1ZBFZ@1386|Bacillus 91061|Bacilli O peptidyl-prolyl isomerase yacD - 5.2.1.8 ko:K07533 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_2,Rotamase_3,SurA_N_3 k141_30124_1 713586.KB900536_gene1443 1.91e-38 141.0 COG0451@1|root,COG0451@2|Bacteria,1MXKV@1224|Proteobacteria,1RNJD@1236|Gammaproteobacteria,1WX9A@135613|Chromatiales 1236|Gammaproteobacteria GM PFAM NAD-dependent epimerase dehydratase arnA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006040,GO:0006139,GO:0006725,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016741,GO:0016742,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0022607,GO:0033319,GO:0033320,GO:0034214,GO:0034641,GO:0034654,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046349,GO:0046483,GO:0046677,GO:0048037,GO:0048040,GO:0050662,GO:0050896,GO:0051259,GO:0051287,GO:0055086,GO:0055114,GO:0065003,GO:0070403,GO:0071704,GO:0071840,GO:0097159,GO:0099618,GO:0099619,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:2001313,GO:2001315 1.1.1.305,2.1.2.13,5.1.3.2 ko:K01784,ko:K10011 ko00052,ko00520,ko01100,ko01503,map00052,map00520,map01100,map01503 M00361,M00362,M00632,M00721,M00761 R00291,R02984,R07658,R07660 RC00026,RC00289,RC01575,RC01812 ko00000,ko00001,ko00002,ko01000,ko01005 - - iPC815.YPO2420,iSFV_1184.SFV_2325 Epimerase,Formyl_trans_C,Formyl_trans_N k141_30124_2 870187.Thini_0382 1.19e-24 96.3 COG3695@1|root,COG3695@2|Bacteria,1N7J2@1224|Proteobacteria,1SCIZ@1236|Gammaproteobacteria,463F1@72273|Thiotrichales 72273|Thiotrichales L PFAM 6-O-methylguanine DNA methyltransferase, DNA binding domain - - - ko:K07443 - - - - ko00000 - - - DNA_binding_1 k141_26926_1 1196031.ALEG01000068_gene4949 1.65e-205 578.0 COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TP5X@1239|Firmicutes,4H9KS@91061|Bacilli,1ZE6P@1386|Bacillus 91061|Bacilli G phosphotransferase system ybbF GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563,GO:0090588 2.7.1.211 ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 M00269 R00811 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.1,4.A.1.2.10,4.A.1.2.12,4.A.1.2.9 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC k141_17138_1 218284.CCDN010000002_gene2388 7.31e-83 259.0 COG3634@1|root,COG3634@2|Bacteria,1TPYN@1239|Firmicutes,4H9W1@91061|Bacilli,1ZCRN@1386|Bacillus 91061|Bacilli O Alkyl hydroperoxide reductase ahpF - - ko:K03387 - - - - ko00000,ko01000 - - - Pyr_redox_2,Thioredoxin_3 k141_6522_1 99598.Cal7507_3737 1.05e-95 310.0 COG3299@1|root,COG3299@2|Bacteria,1G3VV@1117|Cyanobacteria 1117|Cyanobacteria S protein, phage tail-like region - - - - - - - - - - - - Baseplate_J k141_10163_2 218284.CCDN010000002_gene2090 8.6e-97 287.0 COG1024@1|root,COG1024@2|Bacteria,1TQ2V@1239|Firmicutes,4HBT0@91061|Bacilli,1ZE3C@1386|Bacillus 91061|Bacilli I Belongs to the enoyl-CoA hydratase isomerase family paaG - 5.3.3.18 ko:K15866 ko00360,ko01120,map00360,map01120 - R09837,R09839 RC00004,RC00326,RC02689,RC03003 ko00000,ko00001,ko01000 - - - ECH_1 k141_11330_1 218284.CCDN010000001_gene1387 5.47e-111 338.0 COG2905@1|root,COG2905@2|Bacteria,1TQFI@1239|Firmicutes,4HDTM@91061|Bacilli,1ZQQC@1386|Bacillus 91061|Bacilli T Putative nucleotidyltransferase substrate binding domain - - - ko:K07182 - - - - ko00000 - - - CBS,DUF294,DUF294_C,cNMP_binding k141_32503_1 218284.CCDN010000001_gene1975 3.57e-09 53.1 2DFW2@1|root,2ZTE1@2|Bacteria,1W5BA@1239|Firmicutes,4IM45@91061|Bacilli,1ZJ3K@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_19592_1 1111134.HMPREF1253_0370 9.9e-18 85.5 COG4926@1|root,COG4926@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Prophage_tail k141_37309_1 223926.28807368 9.59e-67 206.0 2AVXS@1|root,31MRV@2|Bacteria,1QJIH@1224|Proteobacteria,1THIS@1236|Gammaproteobacteria,1XW66@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF2850) - - - - - - - - - - - - DUF2850 k141_37309_2 1116375.VEJY3_12330 1.27e-306 837.0 COG0548@1|root,COG1246@1|root,COG0548@2|Bacteria,COG1246@2|Bacteria,1MUUP@1224|Proteobacteria,1RMV5@1236|Gammaproteobacteria,1XSV8@135623|Vibrionales 135623|Vibrionales E Amino-acid acetyltransferase argA GO:0003674,GO:0003824,GO:0004042,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1 ko:K14682 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R00259 RC00004,RC00064 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,Acetyltransf_1 k141_37309_4 223926.28807371 2.27e-304 843.0 COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,1RPA0@1236|Gammaproteobacteria,1XTSQ@135623|Vibrionales 135623|Vibrionales L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD recD - 3.1.11.5 ko:K03581 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_30,UvrD_C_2 k141_31363_1 1116375.VEJY3_11270 2.73e-67 216.0 COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,1RMB0@1236|Gammaproteobacteria,1XSGS@135623|Vibrionales 135623|Vibrionales H Belongs to the folylpolyglutamate synthase family folC - 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 - - - Mur_ligase_C,Mur_ligase_M k141_31363_2 1219076.N646_1290 7.5e-109 317.0 COG3147@1|root,COG3147@2|Bacteria,1NGE3@1224|Proteobacteria,1SCGC@1236|Gammaproteobacteria,1XVJ5@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria dedD - - ko:K03749 - - - - ko00000 - - - SPOR k141_31363_3 1219076.N646_1289 2.99e-105 305.0 COG1286@1|root,COG1286@2|Bacteria,1NF4G@1224|Proteobacteria,1RQ58@1236|Gammaproteobacteria,1XSSE@135623|Vibrionales 135623|Vibrionales S membrane protein, required for colicin V production cvpA - - ko:K03558 - - - - ko00000 - - - Colicin_V k141_31363_4 223926.28807178 0.0 951.0 COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,1RMYA@1236|Gammaproteobacteria,1XV4N@135623|Vibrionales 135623|Vibrionales F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine purF - 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase_6,Pribosyltran k141_31363_5 1116375.VEJY3_11245 5.23e-176 493.0 COG0583@1|root,COG0583@2|Bacteria,1R5BA@1224|Proteobacteria,1S4S1@1236|Gammaproteobacteria,1XT26@135623|Vibrionales 135623|Vibrionales K Transcriptional regulator aphB - - ko:K10918 ko05111,map05111 - - - ko00000,ko00001,ko03000 - - - HTH_1,LysR_substrate k141_31363_6 1116375.VEJY3_11240 1.34e-240 664.0 COG2204@1|root,COG2204@2|Bacteria,1QUG8@1224|Proteobacteria,1T1Y0@1236|Gammaproteobacteria,1XT04@135623|Vibrionales 135623|Vibrionales T COG0784 FOG CheY-like receiver rssB - - - - - - - - - - - Response_reg k141_31363_7 1280001.BAOA01000009_gene4114 9.35e-24 89.7 291R7@1|root,2ZPB8@2|Bacteria,1P8GH@1224|Proteobacteria,1SVTR@1236|Gammaproteobacteria,1XYUF@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_31363_8 1116375.VEJY3_11225 2.39e-124 354.0 COG0503@1|root,COG0503@2|Bacteria,1MVZ6@1224|Proteobacteria,1S2N9@1236|Gammaproteobacteria,1XT0Q@135623|Vibrionales 135623|Vibrionales F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis apt GO:0003674,GO:0003824,GO:0003999,GO:0006139,GO:0006166,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0043094,GO:0043101,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046128,GO:0046129,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.7 ko:K00759 ko00230,ko01100,map00230,map01100 - R00190,R01229,R04378 RC00063 ko00000,ko00001,ko01000,ko04147 - - - Pribosyltran k141_31363_9 1116375.VEJY3_11220 0.0 1065.0 COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,1RMIA@1236|Gammaproteobacteria,1XV9Y@135623|Vibrionales 135623|Vibrionales H DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity dnaX - 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNA_pol3_gamma3,DNA_pol3_tau_4,DNA_pol3_tau_5 k141_31363_10 243277.VC_1055 1.11e-65 201.0 COG0718@1|root,COG0718@2|Bacteria,1RGZD@1224|Proteobacteria,1S5WU@1236|Gammaproteobacteria,1XXBA@135623|Vibrionales 135623|Vibrionales S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection ybaB - - ko:K09747 - - - - ko00000 - - - YbaB_DNA_bd k141_31363_11 1219077.VAZ01S_018_00200 6.75e-142 400.0 COG0353@1|root,COG0353@2|Bacteria,1MV9Q@1224|Proteobacteria,1RN99@1236|Gammaproteobacteria,1XUCA@135623|Vibrionales 135623|Vibrionales L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO recR GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - ko:K06187 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecR,Toprim_4 k141_31363_12 1280001.BAOA01000008_gene4107 1.44e-149 423.0 COG0580@1|root,COG0580@2|Bacteria,1MXTJ@1224|Proteobacteria,1RPKU@1236|Gammaproteobacteria,1XV1E@135623|Vibrionales 135623|Vibrionales G Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity aqpZ - - ko:K06188 - - - - ko00000,ko02000 1.A.8 - - MIP k141_31363_13 243277.VC_1057 2.12e-53 167.0 COG0727@1|root,32S46@2|Bacteria,1MZCU@1224|Proteobacteria,1SCG7@1236|Gammaproteobacteria,1XYHX@135623|Vibrionales 135623|Vibrionales S Fe-S-cluster oxidoreductase yeiW - - ko:K06940 - - - - ko00000 - - - CxxCxxCC k141_11620_7 617140.AJZE01000087_gene252 0.0 1011.0 COG4773@1|root,COG4773@2|Bacteria,1QTT0@1224|Proteobacteria,1RNBT@1236|Gammaproteobacteria,1XT1K@135623|Vibrionales 135623|Vibrionales P COG1629 Outer membrane receptor proteins, mostly Fe transport desA - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_11620_8 1116375.VEJY3_07930 1.49e-148 426.0 COG2207@1|root,COG3708@1|root,COG2207@2|Bacteria,COG3708@2|Bacteria,1RBV3@1224|Proteobacteria,1SYIR@1236|Gammaproteobacteria,1XV7W@135623|Vibrionales 135623|Vibrionales K COG2207 AraC-type DNA-binding domain-containing proteins - - - ko:K13653 - - - - ko00000,ko03000 - - - Cass2,GyrI-like,HTH_18 k141_11620_9 1280001.BAOA01000018_gene323 6.86e-43 152.0 COG0364@1|root,COG0364@2|Bacteria,1MUN0@1224|Proteobacteria,1RN76@1236|Gammaproteobacteria,1XSC7@135623|Vibrionales 135623|Vibrionales G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone zwf - 1.1.1.363,1.1.1.49 ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 M00004,M00006,M00008 R00835,R02736,R10907 RC00001,RC00066 ko00000,ko00001,ko00002,ko01000,ko04147 - - - G6PD_C,G6PD_N k141_32757_1 1082705.JIBP01000017_gene903 3.71e-33 117.0 COG0393@1|root,COG0393@2|Bacteria,1N0XM@1224|Proteobacteria,1S62I@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Belongs to the UPF0145 family ybjQ - - - - - - - - - - - YbjQ_1 k141_32757_2 377629.TERTU_4303 2.08e-60 212.0 COG3266@1|root,COG3266@2|Bacteria,1NMZ5@1224|Proteobacteria,1SX8D@1236|Gammaproteobacteria,2PP5X@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria S Domain of unknown function (DUF5011) - - - - - - - - - - - - DUF5011 k141_25868_2 997296.PB1_06627 1.8e-66 202.0 COG0091@1|root,COG0091@2|Bacteria,1V6PU@1239|Firmicutes,4HIK2@91061|Bacilli,1ZG6U@1386|Bacillus 91061|Bacilli J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome rplV GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02890 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L22 k141_22199_1 358681.BBR47_15820 1.5e-54 179.0 COG2186@1|root,COG2186@2|Bacteria,1V5E3@1239|Firmicutes,4HI4R@91061|Bacilli 91061|Bacilli K FadR C-terminal domain - - - ko:K03603 - - - - ko00000,ko03000 - - - FadR_C,GntR k141_27213_1 218284.CCDN010000006_gene3603 3.26e-58 196.0 COG0642@1|root,COG2205@2|Bacteria,1V10X@1239|Firmicutes,4HAU7@91061|Bacilli,1ZB6A@1386|Bacillus 91061|Bacilli T Histidine kinase - - - - - - - - - - - - HAMP,HATPase_c,HisKA k141_27213_2 398511.BpOF4_20184 7.15e-62 203.0 COG2247@1|root,COG2247@2|Bacteria,1UU1U@1239|Firmicutes,4HCNH@91061|Bacilli,1ZDTA@1386|Bacillus 91061|Bacilli M ArsR family transcriptional regulator - - - - - - - - - - - - - k141_31462_1 1395587.P364_0106740 3.08e-08 54.3 COG0454@1|root,COG0456@2|Bacteria,1V2FB@1239|Firmicutes,4HFUN@91061|Bacilli,26V2J@186822|Paenibacillaceae 91061|Bacilli K GNAT family acetyltransferase yhfO - - - - - - - - - - - Acetyltransf_1,Acetyltransf_4 k141_31462_2 218284.CCDN010000001_gene470 7.41e-98 290.0 COG3694@1|root,COG3694@2|Bacteria 2|Bacteria S ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_6 k141_1863_1 938289.CAJN020000002_gene544 8.35e-13 76.3 COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,2683T@186813|unclassified Clostridiales 186801|Clostridia KLT Protein kinase domain prkC - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PASTA,Pkinase k141_24602_1 1294265.JCM21738_4716 6.75e-54 171.0 COG0517@1|root,COG0517@2|Bacteria,1VFAB@1239|Firmicutes,4HRWJ@91061|Bacilli,1ZRSD@1386|Bacillus 91061|Bacilli S COG0517 FOG CBS domain ykuL - - - - - - - - - - - CBS k141_25869_1 1453501.JELR01000001_gene2853 4.4e-58 192.0 COG0477@1|root,COG2814@2|Bacteria,1MVKJ@1224|Proteobacteria,1RMHJ@1236|Gammaproteobacteria,464EA@72275|Alteromonadaceae 1236|Gammaproteobacteria EGP Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family xylE GO:0003674,GO:0005215,GO:0005351,GO:0005402,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0008643,GO:0015075,GO:0015077,GO:0015078,GO:0015144,GO:0015145,GO:0015146,GO:0015148,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015519,GO:0015672,GO:0015749,GO:0015750,GO:0015753,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034219,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 - ko:K05548,ko:K08138,ko:K08139 ko04113,map04113 - - - ko00000,ko00001,ko02000 2.A.1.1,2.A.1.1.3,2.A.1.15 - iECIAI1_1343.ECIAI1_4259,iECSE_1348.ECSE_4322 Sugar_tr k141_22200_1 441769.ABFU01000016_gene915 8.03e-13 63.9 2DRQR@1|root,33CNQ@2|Bacteria,1VGGC@1239|Firmicutes,4HR2A@91061|Bacilli,1ZJ1V@1386|Bacillus 91061|Bacilli S Small, acid-soluble spore protein, gamma-type sspE - - ko:K06422 - - - - ko00000 - - - SASP_gamma k141_22200_2 218284.CCDN010000002_gene2933 5.59e-68 211.0 COG1028@1|root,COG1028@2|Bacteria,1TRVE@1239|Firmicutes,4HCFY@91061|Bacilli,1ZAXT@1386|Bacillus 91061|Bacilli IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) fabL GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.3.1.104 ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00083 R01404,R04430,R04725,R04956,R04959,R04962,R04967,R04970 RC00052,RC00076,RC00120 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 k141_11622_1 218284.CCDN010000001_gene1192 5.18e-30 119.0 COG1413@1|root,COG1413@2|Bacteria,1TRJT@1239|Firmicutes,4HBFD@91061|Bacilli,1ZB7F@1386|Bacillus 91061|Bacilli C COG0694 Thioredoxin-like proteins and domains ypgR - - - - - - - - - - - HEAT_2,HEAT_PBS,Nfu_N,Virulence_fact k141_32758_1 545693.BMQ_3711 2.42e-61 194.0 2CDA7@1|root,333AV@2|Bacteria,1VHFF@1239|Firmicutes,4HRPJ@91061|Bacilli,1ZHIE@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_9218_1 42565.FP66_01815 1.38e-08 54.7 COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,1RMVK@1236|Gammaproteobacteria,1XH7U@135619|Oceanospirillales 135619|Oceanospirillales M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins lgt - - ko:K13292 - - - - ko00000,ko01000 - - - LGT k141_9218_2 42565.FP66_01820 8.65e-169 472.0 COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria,1RPYV@1236|Gammaproteobacteria,1XHH5@135619|Oceanospirillales 135619|Oceanospirillales F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis thyA - 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 - - - Thymidylat_synt k141_12843_1 218284.CCDN010000002_gene2933 4.9e-73 224.0 COG1028@1|root,COG1028@2|Bacteria,1TRVE@1239|Firmicutes,4HCFY@91061|Bacilli,1ZAXT@1386|Bacillus 91061|Bacilli IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) fabL GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.3.1.104 ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00083 R01404,R04430,R04725,R04956,R04959,R04962,R04967,R04970 RC00052,RC00076,RC00120 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 k141_27239_5 1122194.AUHU01000005_gene1054 1.84e-22 91.3 COG1366@1|root,COG1366@2|Bacteria,1MZ5N@1224|Proteobacteria,1S9QR@1236|Gammaproteobacteria,468IN@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) rsbV - - ko:K20978 ko02020,ko02025,map02020,map02025 - - - ko00000,ko00001 - - - STAS_2 k141_3091_1 339670.Bamb_6494 3.14e-32 123.0 COG0662@1|root,COG0836@1|root,COG0662@2|Bacteria,COG0836@2|Bacteria,1MV39@1224|Proteobacteria,2VI4S@28216|Betaproteobacteria,1K0NF@119060|Burkholderiaceae 28216|Betaproteobacteria M Belongs to the mannose-6-phosphate isomerase type 2 family algA - 2.7.7.13,5.3.1.8 ko:K00971,ko:K16011 ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025 M00114,M00361,M00362 R00885,R01819 RC00002,RC00376 ko00000,ko00001,ko00002,ko01000 - - - MannoseP_isomer,NTP_transferase k141_9243_1 1123368.AUIS01000004_gene263 0.00076 47.4 COG1426@1|root,COG1426@2|Bacteria,1N240@1224|Proteobacteria,1RQMV@1236|Gammaproteobacteria,2NC03@225057|Acidithiobacillales 225057|Acidithiobacillales S Helix-turn-helix domain - - - ko:K15539 - - - - ko00000 - - - DUF4115,HTH_25 k141_19866_1 1116375.VEJY3_02450 5.9e-59 183.0 2AWCI@1|root,31N8B@2|Bacteria,1QJZR@1224|Proteobacteria,1TI26@1236|Gammaproteobacteria,1XY7B@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_23557_1 218284.CCDN010000001_gene85 1.97e-119 353.0 COG0771@1|root,COG0771@2|Bacteria,1TQ3P@1239|Firmicutes,4HA5P@91061|Bacilli,1ZARV@1386|Bacillus 91061|Bacilli M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) murD - 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase_C,Mur_ligase_M k141_888_1 343509.SG0881 1.92e-45 159.0 COG1294@1|root,COG1294@2|Bacteria,1MURP@1224|Proteobacteria,1RP7F@1236|Gammaproteobacteria 1236|Gammaproteobacteria C cytochrome d ubiquinol oxidase, subunit cydB GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0016682,GO:0019646,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0070069,GO:0071944,GO:0097159,GO:1901363 1.10.3.14 ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 - iPC815.YPO1118 Cyt_bd_oxida_II k141_17352_1 218284.CCDN010000007_gene3960 6.29e-127 390.0 COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,1TQAD@1239|Firmicutes,4HCMS@91061|Bacilli,1ZBF6@1386|Bacillus 91061|Bacilli EI Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly icmF GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046906,GO:0046983,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 ko:K11942 - - - - ko00000,ko01000 - - - ArgK,B12-binding,MM_CoA_mutase k141_34089_1 42565.FP66_07555 1.41e-111 332.0 COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,1RQ0H@1236|Gammaproteobacteria,1XHQ2@135619|Oceanospirillales 135619|Oceanospirillales E Threonine synthase thrC - 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 - - - PALP,Thr_synth_N k141_18832_1 42565.FP66_09360 2.94e-95 307.0 COG0591@1|root,COG0784@1|root,COG2202@1|root,COG3829@1|root,COG4191@1|root,COG0591@2|Bacteria,COG0784@2|Bacteria,COG2202@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,1QTSW@1224|Proteobacteria,1T1G2@1236|Gammaproteobacteria,1XH3H@135619|Oceanospirillales 135619|Oceanospirillales T COG0591 Na proline symporter - - - - - - - - - - - - HATPase_c,HisKA,PAS_4,PAS_7,Response_reg,SSF k141_20901_1 986075.CathTA2_2048 2.87e-32 125.0 COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,4HAB3@91061|Bacilli 91061|Bacilli JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity cshA GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 3.6.4.13 ko:K05592 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,Helicase_C k141_22229_1 1453501.JELR01000002_gene1492 9.6e-174 509.0 COG1913@1|root,COG1913@2|Bacteria,1MY52@1224|Proteobacteria,1RSIP@1236|Gammaproteobacteria,4646U@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF5117) - - - - - - - - - - - - DUF4953,DUF5117 k141_16219_1 94122.Shewana3_1740 1.57e-292 840.0 COG1404@1|root,COG1404@2|Bacteria,1PE57@1224|Proteobacteria,1RWPJ@1236|Gammaproteobacteria,2QE2X@267890|Shewanellaceae 1236|Gammaproteobacteria O Belongs to the peptidase S8 family - - - - - - - - - - - - - k141_35344_1 857087.Metme_3306 7.15e-102 310.0 COG0430@1|root,COG0430@2|Bacteria,1MX7Q@1224|Proteobacteria,1RSFF@1236|Gammaproteobacteria,1XE7B@135618|Methylococcales 135618|Methylococcales A Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP rtcA GO:0003674,GO:0003824,GO:0003963,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009975,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:1901360 6.5.1.4 ko:K01974 - - - - ko00000,ko01000 - - - RTC,RTC_insert k141_35344_2 1279017.AQYJ01000027_gene1691 6.58e-177 504.0 COG0330@1|root,COG0330@2|Bacteria,1MWMD@1224|Proteobacteria,1RNGH@1236|Gammaproteobacteria,469UH@72275|Alteromonadaceae 1236|Gammaproteobacteria O prohibitin homologues - - - - - - - - - - - - Band_7 k141_31470_1 66692.ABC0960 6.61e-18 84.7 COG1524@1|root,COG1524@2|Bacteria,1TQ3C@1239|Firmicutes,4HBTH@91061|Bacilli,1ZDAI@1386|Bacillus 91061|Bacilli S proteins of the AP superfamily - - - - - - - - - - - - Phosphodiest k141_37500_1 218284.CCDN010000005_gene3410 4.21e-62 191.0 2DZWK@1|root,32VKV@2|Bacteria,1VGZB@1239|Firmicutes,4HKJ4@91061|Bacilli,1ZHSM@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_14148_1 1294265.JCM21738_1349 4.04e-116 333.0 COG2041@1|root,COG2041@2|Bacteria,1V1P9@1239|Firmicutes,4HFQC@91061|Bacilli,1ZD5R@1386|Bacillus 91061|Bacilli S Oxidoreductase molybdopterin binding domain yuiH - - - - - - - - - - - Oxidored_molyb k141_3092_1 218284.CCDN010000002_gene2871 4.05e-29 109.0 COG4565@1|root,COG4565@2|Bacteria,1V1D7@1239|Firmicutes,4HFWB@91061|Bacilli,1ZFEC@1386|Bacillus 91061|Bacilli T response regulator citT - - ko:K11638 ko02020,map02020 M00487 - - ko00000,ko00001,ko00002,ko02022 - - - CitT,HTH_11,Response_reg k141_3092_2 218284.CCDN010000002_gene2872 2.15e-17 80.1 COG3181@1|root,COG3181@2|Bacteria,1V0HH@1239|Firmicutes,4HBWA@91061|Bacilli,1ZB42@1386|Bacillus 91061|Bacilli S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC k141_18833_2 1196031.ALEG01000072_gene924 1.05e-29 108.0 29UM7@1|root,30FYQ@2|Bacteria,1UA1E@1239|Firmicutes,4IKA5@91061|Bacilli,1ZG42@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_36281_1 42565.FP66_01420 1.04e-155 445.0 COG1916@1|root,COG1916@2|Bacteria,1MWJ0@1224|Proteobacteria,1RPND@1236|Gammaproteobacteria,1XNVX@135619|Oceanospirillales 135619|Oceanospirillales S TraB family - - - - - - - - - - - - TraB k141_23559_1 997296.PB1_03315 7.08e-88 262.0 COG1309@1|root,COG1309@2|Bacteria,1V2H2@1239|Firmicutes,4HHJD@91061|Bacilli,1ZFYK@1386|Bacillus 91061|Bacilli K Transcriptional regulator yhgD - - ko:K09017 - - - - ko00000,ko03000 - - - TetR_N k141_14149_1 1123236.KB899378_gene1553 1.52e-87 263.0 COG0463@1|root,COG0463@2|Bacteria,1N8QE@1224|Proteobacteria,1S2RB@1236|Gammaproteobacteria,466RE@72275|Alteromonadaceae 1236|Gammaproteobacteria M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 k141_14149_2 1123236.KB899378_gene1552 1.34e-31 117.0 COG4424@1|root,COG4424@2|Bacteria,1RBDG@1224|Proteobacteria,1SHC5@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Stf0 sulphotransferase - - - - - - - - - - - - Sulphotransf k141_22230_1 1294265.JCM21738_5277 8.7e-71 220.0 COG0583@1|root,COG0583@2|Bacteria,1UXFR@1239|Firmicutes,4HBNZ@91061|Bacilli,1ZE6T@1386|Bacillus 91061|Bacilli K Transcriptional regulator yclA GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:1901363,GO:1990837 - ko:K21755 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate k141_22230_2 1294265.JCM21738_5278 5.48e-93 273.0 COG5577@1|root,COG5577@2|Bacteria,1UPFI@1239|Firmicutes,4IV46@91061|Bacilli 91061|Bacilli M Protein of unknown function (DUF3231) - - - - - - - - - - - - DUF3231 k141_17353_1 314285.KT71_19789 7.76e-12 67.4 COG1874@1|root,COG1874@2|Bacteria 2|Bacteria G beta-galactosidase activity - - 3.2.1.23 ko:K12308 ko00052,map00052 - R01105 RC00452 ko00000,ko00001,ko01000 - - - Glyco_hydro_42,Glyco_hydro_42M k141_14986_1 635013.TherJR_0341 4.12e-26 110.0 COG0697@1|root,COG0697@2|Bacteria,1UZ6C@1239|Firmicutes,24GY3@186801|Clostridia,262MF@186807|Peptococcaceae 186801|Clostridia EG EamA-like transporter family - - - - - - - - - - - - EamA k141_20902_1 1131730.BAVI_16777 1.38e-15 76.6 COG2233@1|root,COG2233@2|Bacteria,1TQ0A@1239|Firmicutes,4HA6X@91061|Bacilli,1ZD5W@1386|Bacillus 91061|Bacilli F Xanthine uracil - - - - - - - - - - - - Xan_ur_permease k141_7873_1 1453501.JELR01000002_gene1334 3.15e-134 408.0 COG2755@1|root,COG2755@2|Bacteria,1MXTS@1224|Proteobacteria,1RTPH@1236|Gammaproteobacteria,46419@72275|Alteromonadaceae 1236|Gammaproteobacteria E Concanavalin A-like lectin/glucanases superfamily - - - - - - - - - - - - Laminin_G_3 k141_7873_2 1279017.AQYJ01000028_gene2080 6.23e-231 642.0 28HN6@1|root,2Z7WJ@2|Bacteria,1R5QB@1224|Proteobacteria,1RNJN@1236|Gammaproteobacteria,4667S@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_7873_3 1453501.JELR01000002_gene1336 0.0 1202.0 COG0823@1|root,COG0823@2|Bacteria,1R3VN@1224|Proteobacteria,1RNKG@1236|Gammaproteobacteria,46408@72275|Alteromonadaceae 1236|Gammaproteobacteria U COG0823 Periplasmic component of the Tol biopolymer transport system - - - - - - - - - - - - PD40 k141_7873_4 1279017.AQYJ01000028_gene2082 9.37e-114 335.0 COG3637@1|root,COG3637@2|Bacteria,1QXK4@1224|Proteobacteria,1T3DI@1236|Gammaproteobacteria,46752@72275|Alteromonadaceae 1236|Gammaproteobacteria M Bacterial SH3 domain - - - - - - - - - - - - OMP_b-brl,SH3_3,SH3_4 k141_7873_5 1453501.JELR01000002_gene1338 3.27e-96 286.0 COG3637@1|root,COG3637@2|Bacteria,1RDPZ@1224|Proteobacteria,1S4GQ@1236|Gammaproteobacteria,467IM@72275|Alteromonadaceae 1236|Gammaproteobacteria M Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - - - - - - - - - - OMP_b-brl k141_7873_6 1279017.AQYJ01000028_gene2084 6e-91 268.0 COG0526@1|root,COG0526@2|Bacteria,1MZ36@1224|Proteobacteria,1S8UU@1236|Gammaproteobacteria,4677J@72275|Alteromonadaceae 1236|Gammaproteobacteria CO Thioredoxin-like resA - - - - - - - - - - - AhpC-TSA,Redoxin k141_7873_7 1279017.AQYJ01000028_gene2085 2.45e-34 118.0 2E3QA@1|root,32YN8@2|Bacteria,1N98P@1224|Proteobacteria,1SCNQ@1236|Gammaproteobacteria,468BH@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF4266) - - - - - - - - - - - - DUF4266 k141_7873_8 1279017.AQYJ01000028_gene2086 7.33e-85 263.0 COG2831@1|root,COG2831@2|Bacteria,1QW38@1224|Proteobacteria,1T2R4@1236|Gammaproteobacteria,464F6@72275|Alteromonadaceae 1236|Gammaproteobacteria U Protein of unknown function (DUF3570) - - - - - - - - - - - - DUF3570 k141_11625_1 1280001.BAOA01000021_gene775 1.25e-79 237.0 COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,1S3QK@1236|Gammaproteobacteria,1XWW2@135623|Vibrionales 135623|Vibrionales J Ribosomal protein L17 rplQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02879 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L17 k141_11625_2 29495.EA26_19605 1.02e-231 638.0 COG0202@1|root,COG0202@2|Bacteria,1MU75@1224|Proteobacteria,1RMU3@1236|Gammaproteobacteria,1XUZ5@135623|Vibrionales 135623|Vibrionales K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoA GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L k141_11625_3 1280001.BAOA01000021_gene773 5.49e-140 396.0 COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,1RQ38@1236|Gammaproteobacteria,1XUJ0@135623|Vibrionales 135623|Vibrionales J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit rpsD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006417,GO:0006450,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112 - ko:K02986 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S4,S4 k141_11625_5 945550.VISI1226_20420 1.24e-73 221.0 COG0099@1|root,COG0099@2|Bacteria,1RD1G@1224|Proteobacteria,1S3NX@1236|Gammaproteobacteria,1XXE1@135623|Vibrionales 135623|Vibrionales J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits rpsM GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02952 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S13 k141_11625_6 223926.28805259 3.93e-305 833.0 COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,1RNJV@1236|Gammaproteobacteria,1XTJ7@135623|Vibrionales 135623|Vibrionales U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently secY GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5 - - SecY k141_11625_7 223926.28805258 1.17e-88 261.0 COG0200@1|root,COG0200@2|Bacteria,1RDC8@1224|Proteobacteria,1S3P6@1236|Gammaproteobacteria,1XWV4@135623|Vibrionales 135623|Vibrionales J Binds to the 23S rRNA rplO GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02876 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27A k141_11625_8 575788.VS_2813 3.27e-32 112.0 COG1841@1|root,COG1841@2|Bacteria,1N6ZE@1224|Proteobacteria,1SC8N@1236|Gammaproteobacteria,1XYYV@135623|Vibrionales 135623|Vibrionales J Ribosomal protein L30 rpmD GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02907 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L30 k141_11625_9 1219076.N646_2465 1.21e-108 313.0 COG0098@1|root,COG0098@2|Bacteria,1MUS4@1224|Proteobacteria,1RNEV@1236|Gammaproteobacteria,1XSIY@135623|Vibrionales 135623|Vibrionales J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body rpsE GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02988 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S5,Ribosomal_S5_C k141_11625_10 1280001.BAOA01000021_gene765 1.51e-69 211.0 COG0256@1|root,COG0256@2|Bacteria,1RGY7@1224|Proteobacteria,1S5V2@1236|Gammaproteobacteria,1XXCG@135623|Vibrionales 135623|Vibrionales J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance rplR GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02881 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L18p k141_11625_11 1280001.BAOA01000021_gene764 2.31e-120 344.0 COG0097@1|root,COG0097@2|Bacteria,1R9YZ@1224|Proteobacteria,1S1Z1@1236|Gammaproteobacteria,1XSZ7@135623|Vibrionales 135623|Vibrionales J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center rplF GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02933 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L6 k141_11625_12 223926.28805253 3.67e-83 246.0 COG0096@1|root,COG0096@2|Bacteria,1RDG3@1224|Proteobacteria,1S452@1236|Gammaproteobacteria,1XWW5@135623|Vibrionales 135623|Vibrionales J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit rpsH GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02994 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S8 k141_11625_13 1219077.VAZ01S_020_00340 1.19e-63 194.0 COG0199@1|root,COG0199@2|Bacteria,1MZDT@1224|Proteobacteria,1S62N@1236|Gammaproteobacteria,1XXE9@135623|Vibrionales 135623|Vibrionales J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site rpsN GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02954 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S14 k141_11625_14 945550.VISI1226_20370 9.78e-123 350.0 COG0094@1|root,COG0094@2|Bacteria,1MUU9@1224|Proteobacteria,1RPE1@1236|Gammaproteobacteria,1XTAU@135623|Vibrionales 135623|Vibrionales J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits rplE GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02931 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L5,Ribosomal_L5_C k141_11625_15 55601.VANGNB10_cI2339c 2.36e-65 199.0 COG0198@1|root,COG0198@2|Bacteria,1MZQD@1224|Proteobacteria,1S973@1236|Gammaproteobacteria,1XX9Z@135623|Vibrionales 135623|Vibrionales J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit rplX GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02895 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KOW,ribosomal_L24 k141_11625_17 674977.VMC_03940 1.43e-54 170.0 COG0186@1|root,COG0186@2|Bacteria,1MZIK@1224|Proteobacteria,1S8SS@1236|Gammaproteobacteria,1XXXG@135623|Vibrionales 135623|Vibrionales J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA rpsQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02961 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S17 k141_11625_18 575788.VS_2823 1.85e-32 113.0 COG0255@1|root,COG0255@2|Bacteria,1N6PR@1224|Proteobacteria,1SCBN@1236|Gammaproteobacteria,1XYAY@135623|Vibrionales 135623|Vibrionales J Belongs to the universal ribosomal protein uL29 family rpmC GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02904 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L29 k141_11625_20 1219076.N646_2454 5.44e-162 454.0 COG0092@1|root,COG0092@2|Bacteria,1MUAI@1224|Proteobacteria,1RN0P@1236|Gammaproteobacteria,1XSCE@135623|Vibrionales 135623|Vibrionales J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation rpsC GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02982 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KH_2,Ribosomal_S3_C k141_11625_21 674977.VMC_03970 2.59e-69 209.0 COG0091@1|root,COG0091@2|Bacteria,1RH0W@1224|Proteobacteria,1S5XT@1236|Gammaproteobacteria,1XX9S@135623|Vibrionales 135623|Vibrionales J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome rplV GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02890 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L22 k141_11625_23 1280001.BAOA01000021_gene752 2.42e-195 541.0 COG0090@1|root,COG0090@2|Bacteria,1MVTD@1224|Proteobacteria,1RMGR@1236|Gammaproteobacteria,1XU36@135623|Vibrionales 135623|Vibrionales J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity rplB GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02886 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L2,Ribosomal_L2_C k141_11625_24 1280001.BAOA01000021_gene751 3.58e-60 186.0 COG0089@1|root,COG0089@2|Bacteria,1MZXX@1224|Proteobacteria,1S8VX@1236|Gammaproteobacteria,1XXSC@135623|Vibrionales 135623|Vibrionales J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome rplW GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02892 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L23 k141_11625_25 945550.VISI1226_20315 8.43e-132 375.0 COG0088@1|root,COG0088@2|Bacteria,1MXPF@1224|Proteobacteria,1RNNK@1236|Gammaproteobacteria,1XSUF@135623|Vibrionales 135623|Vibrionales J Forms part of the polypeptide exit tunnel rplD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02926 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L4 k141_11625_26 1116375.VEJY3_01280 3.05e-143 404.0 COG0087@1|root,COG0087@2|Bacteria,1MUST@1224|Proteobacteria,1RMK9@1236|Gammaproteobacteria,1XSH7@135623|Vibrionales 135623|Vibrionales J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit rplC GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02906 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L3 k141_11625_28 1517681.HW45_27160 1.33e-49 157.0 COG0254@1|root,COG0254@2|Bacteria,1MZ69@1224|Proteobacteria,1SCMH@1236|Gammaproteobacteria,1XYA1@135623|Vibrionales 135623|Vibrionales J Binds the 23S rRNA rpmE GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02909 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L31 k141_11625_29 1219076.N646_2445 7.57e-76 245.0 COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,1RPZ7@1236|Gammaproteobacteria,1XT0R@135623|Vibrionales 135623|Vibrionales L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA priA - - ko:K04066 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C k141_36282_1 1279017.AQYJ01000023_gene3093 3.41e-10 60.1 COG1228@1|root,COG1228@2|Bacteria,1MY4V@1224|Proteobacteria,1RZRK@1236|Gammaproteobacteria,46606@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Amidohydrolase family - - - - - - - - - - - - Amidohydro_1 k141_36282_2 1042377.AFPJ01000052_gene1531 6.04e-65 217.0 COG0620@1|root,COG0620@2|Bacteria,1MUI9@1224|Proteobacteria,1RMBA@1236|Gammaproteobacteria,465YA@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation metE GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0032259,GO:0034641,GO:0035999,GO:0036211,GO:0042084,GO:0042085,GO:0042558,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0050667,GO:0051186,GO:0071704,GO:0140096,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - iE2348C_1286.E2348C_4130,iECO103_1326.ECO103_4334,iECO111_1330.ECO111_4657,iECO26_1355.ECO26_4756,iECW_1372.ECW_m4131,iEKO11_1354.EKO11_4528,iPC815.YPO3788,iWFL_1372.ECW_m4131 Meth_synt_1,Meth_synt_2 k141_28182_1 221288.JH992901_gene1603 2.78e-11 63.5 COG3173@1|root,COG3173@2|Bacteria,1GKJB@1117|Cyanobacteria,1JMB4@1189|Stigonemataceae 1117|Cyanobacteria S Phosphotransferase enzyme family - - - - - - - - - - - - APH k141_33091_2 747365.Thena_0394 8.03e-52 180.0 COG0463@1|root,COG0463@2|Bacteria,1V2EP@1239|Firmicutes,24GAY@186801|Clostridia 186801|Clostridia M group 2 family protein - - - - - - - - - - - - Glycos_transf_2 k141_33091_3 1116375.VEJY3_00935 3.57e-155 441.0 COG1216@1|root,COG1216@2|Bacteria,1QRMS@1224|Proteobacteria,1RUPE@1236|Gammaproteobacteria,1Y1A6@135623|Vibrionales 135623|Vibrionales H Glycosyl transferase, family 2 - - - - - - - - - - - - - k141_24945_1 58123.JOFJ01000004_gene1702 2.34e-16 90.9 COG3291@1|root,COG3291@2|Bacteria,2GN7G@201174|Actinobacteria,4ER4V@85012|Streptosporangiales 201174|Actinobacteria S Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - - - - - - - - - - DUF5122,Malectin,PKD k141_24945_2 1279017.AQYJ01000028_gene2400 4.41e-222 620.0 COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,1RQRP@1236|Gammaproteobacteria,4653Y@72275|Alteromonadaceae 1236|Gammaproteobacteria Q COG1228 Imidazolonepropionase and related amidohydrolases - - - - - - - - - - - - Amidohydro_1 k141_31634_2 1134413.ANNK01000087_gene281 7.86e-92 285.0 COG0422@1|root,COG0422@2|Bacteria,1TNZ3@1239|Firmicutes,4HC0P@91061|Bacilli,1ZBCQ@1386|Bacillus 91061|Bacilli H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction thiC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 ko:K03147 ko00730,ko01100,map00730,map01100 M00127 R03472 RC03251,RC03252 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU08790 ThiC-associated,ThiC_Rad_SAM k141_16499_2 1279017.AQYJ01000013_gene2991 1.86e-70 213.0 COG0690@1|root,COG0690@2|Bacteria,1RDI9@1224|Proteobacteria,1S3PA@1236|Gammaproteobacteria,467U5@72275|Alteromonadaceae 1236|Gammaproteobacteria U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation secE GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecE k141_28205_1 42565.FP66_09535 1.2e-45 163.0 COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,1RMRN@1236|Gammaproteobacteria,1XH4B@135619|Oceanospirillales 135619|Oceanospirillales F Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate purL - 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - AIRS_C,GATase_5 k141_28205_2 42565.FP66_09540 6.32e-26 105.0 COG4623@1|root,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,1RM8W@1236|Gammaproteobacteria,1XI7H@135619|Oceanospirillales 135619|Oceanospirillales M Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella mltF GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - ko:K18691 - - - - ko00000,ko01000,ko01011 - - - SBP_bac_3,SLT k141_29644_1 935836.JAEL01000003_gene399 2.63e-24 100.0 COG1270@1|root,COG1270@2|Bacteria,1TQ3X@1239|Firmicutes,4HA48@91061|Bacilli,1ZCDR@1386|Bacillus 91061|Bacilli H Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group cobD - 6.3.1.10 ko:K02227 ko00860,ko01100,map00860,map01100 M00122 R06529,R07302 RC00090,RC00096 ko00000,ko00001,ko00002,ko01000 - - - CobD_Cbib k141_29644_2 1403313.AXBR01000027_gene5302 5.57e-37 135.0 COG0079@1|root,COG0079@2|Bacteria,1TP5D@1239|Firmicutes,4HD85@91061|Bacilli,1ZC9F@1386|Bacillus 91061|Bacilli E COG0079 Histidinol-phosphate aromatic aminotransferase and cobyric acid decarboxylase cobD - 4.1.1.81 ko:K04720 ko00860,map00860 - R06530 RC00517 ko00000,ko00001,ko01000 - - - Aminotran_1_2 k141_36474_1 218284.CCDN010000001_gene1736 5.59e-85 268.0 COG0075@1|root,COG3916@1|root,COG0075@2|Bacteria,COG3916@2|Bacteria,1TR3I@1239|Firmicutes,4HA6W@91061|Bacilli,1ZAT2@1386|Bacillus 91061|Bacilli E Aminotransferase class-V - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10,Acetyltransf_5,Acetyltransf_9,Aminotran_5 k141_21162_1 218284.CCDN010000002_gene2168 1.09e-222 627.0 COG1164@1|root,COG1164@2|Bacteria,1TQ5W@1239|Firmicutes,4HAN9@91061|Bacilli,1ZCRR@1386|Bacillus 91061|Bacilli E COG1164 Oligoendopeptidase F pepF2 - - - - - - - - - - - Peptidase_M3,Peptidase_M3_N k141_31635_2 1294265.JCM21738_2862 1.61e-85 256.0 COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,4HA98@91061|Bacilli,1ZDG5@1386|Bacillus 91061|Bacilli JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures cshB GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0070035,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 3.6.4.13 ko:K05592,ko:K18692 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,Helicase_C k141_28206_1 218284.CCDN010000002_gene2226 3.74e-100 303.0 COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,4H9SZ@91061|Bacilli,1ZAX7@1386|Bacillus 91061|Bacilli E Sodium alanine symporter yflA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03310 - - - - ko00000 2.A.25 - - Na_Ala_symp k141_2142_1 1042377.AFPJ01000007_gene1766 1.35e-305 857.0 COG0243@1|root,COG0243@2|Bacteria,1MU6B@1224|Proteobacteria,1RNXW@1236|Gammaproteobacteria,4651W@72275|Alteromonadaceae 1236|Gammaproteobacteria C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family ydeP - 1.17.1.9 ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001,ko01000 - - - Molybdopterin,Molydop_binding k141_16500_2 1246484.D479_15737 7.24e-80 245.0 COG2761@1|root,COG2761@2|Bacteria,1TQ8K@1239|Firmicutes,4HAI8@91061|Bacilli,3ND5A@45667|Halobacillus 91061|Bacilli Q Thioredoxin yjbH - - - - - - - - - - - Thioredoxin_5 k141_37777_1 1232410.KI421428_gene998 3.68e-79 249.0 COG4240@1|root,COG4240@2|Bacteria,1QUTA@1224|Proteobacteria,42YFA@68525|delta/epsilon subdivisions,2WUFH@28221|Deltaproteobacteria,43TBS@69541|Desulfuromonadales 28221|Deltaproteobacteria S COG4240 Predicted kinase - - - - - - - - - - - - - k141_37777_2 1279017.AQYJ01000022_gene2593 2.14e-292 830.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,464R3@72275|Alteromonadaceae 1236|Gammaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K18989 - M00720 - - ko00000,ko00002,ko02000 2.A.6.2.30 - - ACR_tran k141_10585_2 94122.Shewana3_0113 3.27e-84 255.0 COG4461@1|root,COG4461@2|Bacteria,1R6Q3@1224|Proteobacteria,1S2QD@1236|Gammaproteobacteria,2Q9NS@267890|Shewanellaceae 1236|Gammaproteobacteria S Lysozyme inhibitor LprI - - - - - - - - - - - - LprI,MliC k141_10585_3 1453501.JELR01000002_gene51 1.51e-265 734.0 COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,1RPU5@1236|Gammaproteobacteria,46411@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0471 Di- and tricarboxylate transporters sdcS - - ko:K14445 - - - - ko00000,ko02000 2.A.47.1 - - Na_sulph_symp k141_10585_5 1453501.JELR01000001_gene2234 5.39e-97 293.0 COG0639@1|root,COG0639@2|Bacteria,1N106@1224|Proteobacteria,1S9QJ@1236|Gammaproteobacteria,468J4@72275|Alteromonadaceae 1236|Gammaproteobacteria T Calcineurin-like phosphoesterase - - 3.1.3.16 ko:K07313 - - - - ko00000,ko01000 - - - Metallophos k141_10585_6 1005048.CFU_3459 1.29e-170 494.0 COG1028@1|root,COG1028@2|Bacteria,1MXRY@1224|Proteobacteria,2VMYM@28216|Betaproteobacteria,4768U@75682|Oxalobacteraceae 28216|Betaproteobacteria IQ KR domain - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 k141_10585_7 1095769.CAHF01000009_gene1424 8.63e-144 416.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2VIX2@28216|Betaproteobacteria,47673@75682|Oxalobacteraceae 28216|Betaproteobacteria I Thiolase, C-terminal domain - - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N k141_33094_1 218284.CCDN010000005_gene3229 4.12e-105 334.0 COG1074@1|root,COG1074@2|Bacteria,1TQ35@1239|Firmicutes,4HA64@91061|Bacilli,1ZBG6@1386|Bacillus 91061|Bacilli L ATP-dependent helicase nuclease subunit A addA GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 3.6.4.12 ko:K16898 - - - - ko00000,ko01000,ko03400 - - - PDDEXK_1,UvrD-helicase,UvrD_C k141_15196_1 935836.JAEL01000098_gene1455 1.88e-206 585.0 COG0481@1|root,COG0481@2|Bacteria,1TP0G@1239|Firmicutes,4HASA@91061|Bacilli,1ZC7J@1386|Bacillus 91061|Bacilli M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner lepA - - ko:K03596 ko05134,map05134 - - - ko00000,ko00001 - - - EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C k141_15196_2 1294265.JCM21738_3285 3.37e-31 118.0 COG0635@1|root,COG0635@2|Bacteria,1TPES@1239|Firmicutes,4HA60@91061|Bacilli,1ZC7V@1386|Bacillus 91061|Bacilli H Involved in the biosynthesis of porphyrin-containing compound hemN GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - - - - - - - - - - HemN_C,Radical_SAM k141_2144_1 666686.B1NLA3E_18635 9.39e-07 47.0 COG4844@1|root,COG4844@2|Bacteria,1VFJJ@1239|Firmicutes,4HNQ8@91061|Bacilli,1ZHVJ@1386|Bacillus 91061|Bacilli S Belongs to the UPF0349 family yuzB - - - - - - - - - - - DUF1450 k141_2144_2 1294265.JCM21738_1366 1.75e-74 228.0 COG1655@1|root,COG1655@2|Bacteria,1UY0V@1239|Firmicutes,4HDH4@91061|Bacilli,1ZD58@1386|Bacillus 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2225) - - - ko:K09766 - - - - ko00000 - - - DUF2225 k141_29647_1 218284.CCDN010000001_gene594 2.17e-125 377.0 COG0466@1|root,COG0466@2|Bacteria,1TNYG@1239|Firmicutes,4HAZK@91061|Bacilli,1ZAXX@1386|Bacillus 91061|Bacilli O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner lon GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.4.21.53 ko:K01338 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - AAA,LON_substr_bdg,Lon_C k141_21164_1 1294265.JCM21738_3670 4.14e-106 307.0 COG0801@1|root,COG0801@2|Bacteria,1V6PR@1239|Firmicutes,4HIMG@91061|Bacilli,1ZGBC@1386|Bacillus 91061|Bacilli H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase folK - 2.7.6.3 ko:K00950 ko00790,ko01100,map00790,map01100 M00126,M00841 R03503 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - HPPK k141_21164_2 796606.BMMGA3_00445 1.1e-27 101.0 COG1396@1|root,COG1396@2|Bacteria,1VIT6@1239|Firmicutes,4HP4J@91061|Bacilli,1ZJ4Q@1386|Bacillus 91061|Bacilli K transcriptional yazB - - - - - - - - - - - HTH_3 k141_17654_1 1116375.VEJY3_18961 1.14e-149 425.0 COG1879@1|root,COG1879@2|Bacteria,1NRXG@1224|Proteobacteria,1RPBV@1236|Gammaproteobacteria,1XUF5@135623|Vibrionales 135623|Vibrionales G ABC-type sugar transport system, periplasmic component rbsB - - ko:K10439 ko02010,ko02030,map02010,map02030 M00212 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - Peripla_BP_4 k141_17654_2 223926.28809386 1.08e-139 400.0 COG1172@1|root,COG1172@2|Bacteria,1MX7D@1224|Proteobacteria,1RNTS@1236|Gammaproteobacteria,1XTC8@135623|Vibrionales 135623|Vibrionales G Belongs to the binding-protein-dependent transport system permease family rbsC - - ko:K10440 ko02010,map02010 M00212 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - BPD_transp_2 k141_30500_2 218284.CCDN010000002_gene2144 5.14e-98 298.0 COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,4H9W6@91061|Bacilli,1ZD0J@1386|Bacillus 91061|Bacilli G Belongs to the FGGY kinase family gntK - 2.7.1.12 ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 - R01737 RC00002,RC00017 ko00000,ko00001,ko01000 - - - FGGY_C,FGGY_N k141_33095_1 1453501.JELR01000002_gene783 1.62e-181 531.0 COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,1RQEX@1236|Gammaproteobacteria,463Z7@72275|Alteromonadaceae 1236|Gammaproteobacteria M Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane lptD GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0009279,GO:0009636,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0042221,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0050896,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:1901264 - ko:K04744 - - - - ko00000,ko02000 1.B.42.1 - iG2583_1286.G2583_0058 OstA,OstA_C k141_4575_1 223926.28806637 0.0 1099.0 COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,1RN5I@1236|Gammaproteobacteria,1XTEH@135623|Vibrionales 135623|Vibrionales C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate acnA - 4.2.1.117 ko:K20455 ko00640,map00640 - R11263 RC01152 ko00000,ko00001,ko01000 - - - Aconitase,Aconitase_C k141_4575_2 223926.28806636 1.49e-272 747.0 COG2828@1|root,COG2828@2|Bacteria,1MXVV@1224|Proteobacteria,1RNE6@1236|Gammaproteobacteria,1XT0G@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria prpF - - ko:K09788 ko00640,map00640 - R11264 RC03405 ko00000,ko00001,ko01000 - - - PrpF k141_28209_1 698769.JFBD01000081_gene64 8.62e-29 111.0 COG0157@1|root,COG0157@2|Bacteria,1TPQC@1239|Firmicutes,4HB46@91061|Bacilli,4C5FA@84406|Virgibacillus 91061|Bacilli H Quinolinate phosphoribosyl transferase, C-terminal domain nadC GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034213,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 2.4.2.19 ko:K00767 ko00760,ko01100,map00760,map01100 M00115 R03348 RC02877 ko00000,ko00001,ko00002,ko01000 - - - QRPTase_C,QRPTase_N k141_28209_2 218284.CCDN010000001_gene644 2.66e-93 282.0 COG0379@1|root,COG0379@2|Bacteria,1TP6R@1239|Firmicutes,4H9QG@91061|Bacilli,1ZAR3@1386|Bacillus 91061|Bacilli H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate nadA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 ko:K03517 ko00760,ko01100,map00760,map01100 M00115 R04292 RC01119 ko00000,ko00001,ko00002,ko01000 - - - NadA k141_37780_1 218284.CCDN010000001_gene1528 3.73e-212 590.0 COG0006@1|root,COG0006@2|Bacteria,1TQ6R@1239|Firmicutes,4HA5I@91061|Bacilli,1ZBZE@1386|Bacillus 91061|Bacilli E COG0006 Xaa-Pro aminopeptidase ykvY - 3.4.13.9 ko:K01271 - - - - ko00000,ko01000,ko01002 - - - Creatinase_N,Peptidase_M24 k141_10586_1 1216007.AOPM01000059_gene1745 0.000355 43.5 COG0491@1|root,COG0491@2|Bacteria,1PBS8@1224|Proteobacteria,1RS4P@1236|Gammaproteobacteria,2Q09T@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B k141_10586_2 1056820.KB900700_gene1015 2.51e-79 239.0 COG0454@1|root,COG0456@2|Bacteria,1QU0C@1224|Proteobacteria,1S503@1236|Gammaproteobacteria,2PPW4@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1 k141_30501_1 218284.CCDN010000008_gene4247 7.27e-97 307.0 COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H9SA@91061|Bacilli,1ZD7B@1386|Bacillus 91061|Bacilli M COG0744 Membrane carboxypeptidase (penicillin-binding protein) pbp1B - 2.4.1.129 ko:K03693,ko:K12551 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase k141_2146_1 1347086.CCBA010000005_gene4074 2.55e-116 365.0 COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,4HAFP@91061|Bacilli,1ZBJ3@1386|Bacillus 91061|Bacilli V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran k141_34351_1 1453501.JELR01000002_gene1049 2.53e-20 92.4 COG2234@1|root,COG2234@2|Bacteria,1MUZ7@1224|Proteobacteria,1RS0Q@1236|Gammaproteobacteria,4653N@72275|Alteromonadaceae 1236|Gammaproteobacteria S PA domain - - - - - - - - - - - - PA,Peptidase_M28 k141_34351_2 1279017.AQYJ01000027_gene1726 1.24e-114 335.0 28Q1W@1|root,2ZCK4@2|Bacteria,1RE1D@1224|Proteobacteria,1T19A@1236|Gammaproteobacteria,46D1X@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_33096_1 797114.C475_02181 1.24e-13 75.9 COG0750@1|root,arCOG00609@2157|Archaea,2XT29@28890|Euryarchaeota,23SIQ@183963|Halobacteria 183963|Halobacteria M membrane-associated Zn-dependent proteases 1 - - - - - - - - - - - - Peptidase_M50 k141_3375_1 1502852.FG94_01144 2.04e-11 65.9 COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VJUT@28216|Betaproteobacteria,476W7@75682|Oxalobacteraceae 28216|Betaproteobacteria T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA,MASE1 k141_3375_2 1379270.AUXF01000003_gene3386 2.72e-24 103.0 COG2204@1|root,COG2204@2|Bacteria,1ZSRQ@142182|Gemmatimonadetes 142182|Gemmatimonadetes T Bacterial regulatory protein, Fis family - - - - - - - - - - - - HTH_8,Response_reg,Sigma54_activat k141_10587_1 218284.CCDN010000002_gene2131 2.67e-82 253.0 COG0513@1|root,COG0513@2|Bacteria,1TQ9R@1239|Firmicutes,4HANR@91061|Bacilli,1ZC9I@1386|Bacillus 91061|Bacilli L COG0513 Superfamily II DNA and RNA helicases yfmL GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - - - - - - - - - - DEAD,Helicase_C k141_29649_1 218284.CCDN010000001_gene958 7.59e-27 103.0 2E7KE@1|root,3322G@2|Bacteria,1VG6C@1239|Firmicutes,4HNMG@91061|Bacilli,1ZH76@1386|Bacillus 91061|Bacilli S Stage III sporulation protein AF (Spore_III_AF) spoIIIAF - - ko:K06395 - - - - ko00000 - - - Spore_III_AF k141_29649_2 218284.CCDN010000001_gene959 1.24e-61 194.0 2E6BB@1|root,330Z5@2|Bacteria,1VF3M@1239|Firmicutes,4HH7J@91061|Bacilli,1ZEMQ@1386|Bacillus 91061|Bacilli S stage III sporulation protein AG spoIIIAG - - ko:K06396 - - - - ko00000 - - - - k141_37782_1 1042377.AFPJ01000004_gene352 1.13e-106 325.0 COG0366@1|root,COG0366@2|Bacteria,1MU90@1224|Proteobacteria,1RQ1S@1236|Gammaproteobacteria,464Q7@72275|Alteromonadaceae 1236|Gammaproteobacteria G Belongs to the glycosyl hydrolase 13 family - - 3.2.1.135 ko:K21575 - - - - ko00000,ko01000 - GH13 - Alpha-amylase,Cyc-maltodext_C,Cyc-maltodext_N k141_21165_1 223926.28805121 5.6e-120 347.0 COG4795@1|root,COG4795@2|Bacteria,1RJAE@1224|Proteobacteria,1S5ZZ@1236|Gammaproteobacteria,1XU01@135623|Vibrionales 135623|Vibrionales U general secretion pathway protein epsJ GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0098776 - ko:K02459 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - N_methyl,T2SSJ k141_21165_2 1116375.VEJY3_00645 2.62e-190 533.0 COG3156@1|root,COG3156@2|Bacteria,1RC9P@1224|Proteobacteria,1T072@1236|Gammaproteobacteria,1XT6W@135623|Vibrionales 135623|Vibrionales U COG3156 Type II secretory pathway, component PulK epsK - - ko:K02460 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSK k141_36477_1 102125.Xen7305DRAFT_00004000 4.17e-52 186.0 COG3659@1|root,COG3659@2|Bacteria 2|Bacteria M wide pore channel activity - - - ko:K07267 - - - - ko00000,ko02000 1.B.19.1 - - OprB k141_36477_2 1267534.KB906754_gene2985 1.5e-54 184.0 COG3637@1|root,COG3637@2|Bacteria 2|Bacteria M Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - ko:K03286 - - - - ko00000,ko02000 1.B.6 - - OMP_b-brl,Porin_O_P k141_10588_1 768066.HELO_3963 2.86e-95 290.0 COG0015@1|root,COG0015@2|Bacteria,1MXNN@1224|Proteobacteria,1RS00@1236|Gammaproteobacteria,1XQ0J@135619|Oceanospirillales 135619|Oceanospirillales F Adenylosuccinate lyase C-terminus - - 5.5.1.2 ko:K01857 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 - R03307 RC00902 ko00000,ko00001,ko01000 - - - ADSL_C,Lyase_1 k141_4579_2 1453501.JELR01000002_gene847 9.05e-119 343.0 COG3717@1|root,COG3717@2|Bacteria,1MU9D@1224|Proteobacteria,1RPDB@1236|Gammaproteobacteria,465F3@72275|Alteromonadaceae 1236|Gammaproteobacteria G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate kduI - 5.3.1.17 ko:K01815 ko00040,map00040 - R04383 RC00541 ko00000,ko00001,ko01000 - - - KduI k141_29650_1 1196031.ALEG01000072_gene946 1.36e-24 99.4 COG2137@1|root,COG2137@2|Bacteria,1V72V@1239|Firmicutes,4HJ7R@91061|Bacilli,1ZC8N@1386|Bacillus 91061|Bacilli S Modulates RecA activity recX - - ko:K03565 - - - - ko00000,ko03400 - - - RecX k141_29650_2 1294265.JCM21738_3365 1.32e-57 186.0 COG1090@1|root,COG1090@2|Bacteria,1TRCE@1239|Firmicutes,4HBRT@91061|Bacilli,1ZBKW@1386|Bacillus 91061|Bacilli S nucleoside-diphosphate sugar epimerase yfhF - - ko:K07071 - - - - ko00000 - - - DUF1731,Epimerase k141_24951_1 1453501.JELR01000001_gene2124 2.72e-86 262.0 COG3806@1|root,COG3806@2|Bacteria,1RI6T@1224|Proteobacteria,1S2IS@1236|Gammaproteobacteria,46DNT@72275|Alteromonadaceae 1236|Gammaproteobacteria T AntiSigma factor chrR - - ko:K07167 - - - - ko00000 - - - Cupin_7 k141_4609_9 1219076.N646_2100 4.77e-147 415.0 COG1738@1|root,COG1738@2|Bacteria,1MVQU@1224|Proteobacteria,1RNX0@1236|Gammaproteobacteria,1XV4J@135623|Vibrionales 135623|Vibrionales U Involved in the import of queuosine (Q) precursors, required for Q precursor salvage yhhQ - - ko:K09125 - - - - ko00000 - - - Vut_1 k141_4609_10 1116375.VEJY3_15145 7.18e-65 197.0 2EQ7T@1|root,33HU2@2|Bacteria,1NI3T@1224|Proteobacteria,1SHPX@1236|Gammaproteobacteria,1XYF0@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF3630) - - - - - - - - - - - - DUF3630 k141_4609_11 674977.VMC_02050 6.8e-126 375.0 COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,1RMPG@1236|Gammaproteobacteria,1XU5H@135623|Vibrionales 135623|Vibrionales L DNA helicase recQ - 3.6.4.12 ko:K03654 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind k141_28242_1 1453501.JELR01000002_gene1163 2.26e-181 521.0 COG3449@1|root,COG3449@2|Bacteria,1QU1G@1224|Proteobacteria,1RSNB@1236|Gammaproteobacteria,46732@72275|Alteromonadaceae 1236|Gammaproteobacteria L Domain of unknown function (DUF4153) yhgE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - DUF4153 k141_34404_1 218284.CCDN010000002_gene1989 8.61e-167 476.0 COG0034@1|root,COG0034@2|Bacteria,1TPH3@1239|Firmicutes,4HAXU@91061|Bacilli,1ZCE0@1386|Bacillus 91061|Bacilli F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine purF - 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 - - iSB619.SA_RS05225 GATase_6,GATase_7,Pribosyltran k141_16549_1 1294265.JCM21738_2435 1.19e-77 241.0 COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,4HA95@91061|Bacilli,1ZCW9@1386|Bacillus 91061|Bacilli E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids alr - 5.1.1.1,5.1.1.5 ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 - R00401 RC00285 ko00000,ko00001,ko01000,ko01011 - - - Ala_racemase_C,Ala_racemase_N k141_10639_2 997296.PB1_13844 3.82e-17 80.1 2EGVD@1|root,33AMM@2|Bacteria,1VKVK@1239|Firmicutes,4HRYS@91061|Bacilli,1ZITC@1386|Bacillus 91061|Bacilli - - ypoC - - - - - - - - - - - - k141_28243_2 218284.CCDN010000001_gene1070 1.21e-52 177.0 COG4955@1|root,COG4955@2|Bacteria,1TQU9@1239|Firmicutes,4HFUR@91061|Bacilli,1ZDGR@1386|Bacillus 91061|Bacilli S protein conserved in bacteria ypbB - 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 - - - HTH_40,RQC k141_4611_1 1294265.JCM21738_5064 3.54e-129 370.0 COG0561@1|root,COG0561@2|Bacteria,1TREF@1239|Firmicutes,4H9Y9@91061|Bacilli,1ZC4W@1386|Bacillus 91061|Bacilli S hydrolases of the HAD superfamily yitU - 3.1.3.104 ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R07280 RC00017 ko00000,ko00001,ko00002,ko01000 - - - Hydrolase_3 k141_33137_1 218284.CCDN010000004_gene3153 1.79e-96 295.0 COG0189@1|root,COG0189@2|Bacteria,1V1EV@1239|Firmicutes,4HFNI@91061|Bacilli,1ZBM5@1386|Bacillus 91061|Bacilli HJ YheC/D like ATP-grasp - - - - - - - - - - - - ATPgrasp_YheCD k141_28244_1 1347086.CCBA010000022_gene2938 1.34e-111 332.0 COG0719@1|root,COG0719@2|Bacteria,1TQ21@1239|Firmicutes,4HA1Z@91061|Bacilli,1ZCDS@1386|Bacillus 91061|Bacilli O FeS cluster assembly sufB - - ko:K07033,ko:K09014 - - - - ko00000 - - - UPF0051 k141_10640_1 1121939.L861_20900 1.51e-102 309.0 COG3135@1|root,COG3135@2|Bacteria,1MUS1@1224|Proteobacteria,1RMD5@1236|Gammaproteobacteria,1XIU5@135619|Oceanospirillales 135619|Oceanospirillales Q Benzoate membrane transport protein - - - ko:K05782 - - - - ko00000,ko02000 2.A.46.1 - - BenE k141_36531_1 42565.FP66_13525 2.87e-60 189.0 COG4123@1|root,COG4123@2|Bacteria,1QUWW@1224|Proteobacteria,1T24A@1236|Gammaproteobacteria,1XRRX@135619|Oceanospirillales 135619|Oceanospirillales S Methionine biosynthesis protein MetW metW - - - - - - - - - - - MetW k141_36531_2 42565.FP66_13530 2.24e-63 203.0 COG2021@1|root,COG2021@2|Bacteria,1MVJV@1224|Proteobacteria,1RQ2N@1236|Gammaproteobacteria,1XHTS@135619|Oceanospirillales 135619|Oceanospirillales E Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine metX - 2.3.1.31 ko:K00641 ko00270,ko01100,ko01130,map00270,map01100,map01130 - R01776 RC00004,RC00041 ko00000,ko00001,ko01000 - - - Abhydrolase_1 k141_29696_1 1116375.VEJY3_19441 1.84e-165 474.0 COG0446@1|root,COG0446@2|Bacteria,1MXA9@1224|Proteobacteria,1RYAH@1236|Gammaproteobacteria,1Y2J3@135623|Vibrionales 135623|Vibrionales C BFD-like [2Fe-2S] binding domain - - - - - - - - - - - - Fer2_BFD,Pyr_redox_2 k141_29696_2 1116375.VEJY3_19446 4.87e-75 224.0 COG0251@1|root,COG0251@2|Bacteria,1MZ5K@1224|Proteobacteria,1SRUB@1236|Gammaproteobacteria,1XY7A@135623|Vibrionales 135623|Vibrionales J Endoribonuclease L-PSP - - - - - - - - - - - - Ribonuc_L-PSP k141_34407_1 935837.JAEK01000056_gene2500 2.81e-84 265.0 COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,4H9RY@91061|Bacilli,1ZE2W@1386|Bacillus 91061|Bacilli S MviN-like protein - - - - - - - - - - - - Polysacc_synt,Polysacc_synt_C k141_31688_2 218284.CCDN010000001_gene1395 1.13e-45 161.0 COG1396@1|root,COG1396@2|Bacteria,1U4VN@1239|Firmicutes,4HE98@91061|Bacilli,1ZDJQ@1386|Bacillus 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - ko:K20480 ko02024,map02024 - - - ko00000,ko00001,ko03000 - - - HTH_3,TPR_12,TPR_7,TPR_8 k141_15247_1 877418.ATWV01000003_gene493 0.000205 50.1 COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,2J6FV@203691|Spirochaetes 203691|Spirochaetes T Adenylate guanylate cyclase catalytic domain protein - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - CHASE2,Guanylate_cyc k141_16550_1 318167.Sfri_1309 7.59e-206 581.0 COG0446@1|root,COG0446@2|Bacteria,1Q0P8@1224|Proteobacteria,1T1NQ@1236|Gammaproteobacteria,2QAD4@267890|Shewanellaceae 1236|Gammaproteobacteria S Tryptophan halogenase - - 1.14.19.9 ko:K14266 ko00404,ko01130,map00404,map01130 M00789,M00790 R09570 RC00949 ko00000,ko00001,ko00002,ko01000 - - - Trp_halogenase k141_17711_1 1279017.AQYJ01000021_gene2781 1.53e-316 886.0 COG3127@1|root,COG3127@2|Bacteria,1MU9R@1224|Proteobacteria,1RM8Y@1236|Gammaproteobacteria,4654Y@72275|Alteromonadaceae 1236|Gammaproteobacteria Q ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component ybbP GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX k141_17711_2 1453501.JELR01000002_gene78 1.47e-25 101.0 COG4181@1|root,COG4181@2|Bacteria,1MXG9@1224|Proteobacteria,1RMG1@1236|Gammaproteobacteria,466GJ@72275|Alteromonadaceae 1236|Gammaproteobacteria Q ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component ybbA GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_9597_3 1116375.VEJY3_20056 6.81e-274 752.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1XTY4@135623|Vibrionales 135623|Vibrionales JKL Belongs to the DEAD box helicase family - - 3.6.4.13 ko:K11927 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - DEAD,Helicase_C k141_9597_4 223926.28809081 9.8e-141 402.0 COG2200@1|root,COG2200@2|Bacteria,1N50H@1224|Proteobacteria,1SYN8@1236|Gammaproteobacteria,1XUYQ@135623|Vibrionales 135623|Vibrionales T COG2200 FOG EAL domain - - - - - - - - - - - - EAL k141_9597_5 1116375.VEJY3_20046 6.65e-143 404.0 2AVVY@1|root,31MPS@2|Bacteria,1QJH3@1224|Proteobacteria,1THGW@1236|Gammaproteobacteria,1XVRR@135623|Vibrionales 135623|Vibrionales - - VCA0537 - - - - - - - - - - - - k141_9597_6 1219076.N646_4240 1.43e-41 137.0 COG5460@1|root,COG5460@2|Bacteria,1N7MS@1224|Proteobacteria,1SCTR@1236|Gammaproteobacteria,1XYUK@135623|Vibrionales 135623|Vibrionales S Uncharacterized conserved protein (DUF2164) - - - - - - - - - - - - DUF2164 k141_9597_7 674977.VMC_42820 4.8e-114 328.0 COG3038@1|root,COG3038@2|Bacteria,1MZ7X@1224|Proteobacteria,1S3RF@1236|Gammaproteobacteria,1XWWE@135623|Vibrionales 135623|Vibrionales C Cytochrome b561 - - - ko:K12262 - - - - ko00000 - - - Ni_hydr_CYTB k141_9597_8 1116375.VEJY3_20031 3.1e-81 243.0 COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,1S24R@1236|Gammaproteobacteria,1XUIB@135623|Vibrionales 135623|Vibrionales S UPF0312 protein - - - - - - - - - - - - YceI k141_26285_1 935836.JAEL01000068_gene1774 1.25e-69 218.0 COG4821@1|root,COG4821@2|Bacteria,1TQS7@1239|Firmicutes,4HCR4@91061|Bacilli,1ZAP1@1386|Bacillus 91061|Bacilli S carbohydrate derivative metabolic process - - - - - - - - - - - - SIS_2 k141_6091_1 1196029.ALIM01000033_gene1494 8.98e-64 214.0 COG0476@1|root,COG0476@2|Bacteria,1UZJC@1239|Firmicutes,4HB2K@91061|Bacilli,1ZBN2@1386|Bacillus 91061|Bacilli H bacteriocin maturation protein - - - - - - - - - - - - - k141_13228_1 1195246.AGRI_12676 2.93e-97 318.0 COG3868@1|root,COG3868@2|Bacteria,1MXYK@1224|Proteobacteria,1RMK1@1236|Gammaproteobacteria,46A7Q@72275|Alteromonadaceae 1236|Gammaproteobacteria S Glycoside-hydrolase family GH114 pelA - - ko:K21006 ko02025,map02025 - - - ko00000,ko00001 - - - Glyco_hydro_114 k141_31047_1 1453501.JELR01000002_gene1490 4.84e-128 370.0 COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,1RZAD@1236|Gammaproteobacteria,46890@72275|Alteromonadaceae 1236|Gammaproteobacteria E Aminotransferase class I and II hisC2 - 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k141_15608_1 1279017.AQYJ01000027_gene1812 6.72e-57 179.0 COG3312@1|root,COG3312@2|Bacteria,1N777@1224|Proteobacteria,1SD0Z@1236|Gammaproteobacteria,468Z4@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG3312 F0F1-type ATP synthase, subunit I atpI GO:0003674,GO:0003824,GO:0005215,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044769,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02116 - - - - ko00000,ko00194 3.A.2.1 - - ATP-synt_I k141_15608_2 1453501.JELR01000002_gene1126 2.11e-189 530.0 COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,1RPHK@1236|Gammaproteobacteria,464QZ@72275|Alteromonadaceae 1236|Gammaproteobacteria C it plays a direct role in the translocation of protons across the membrane atpB GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 - iAPECO1_1312.APECO1_2725,iE2348C_1286.E2348C_4048,iEC042_1314.EC042_4125,iECABU_c1320.ECABU_c42230,iECED1_1282.ECED1_4428,iECIAI39_1322.ECIAI39_4342,iECNA114_1301.ECNA114_3887,iECOK1_1307.ECOK1_4187,iECP_1309.ECP_3937,iECS88_1305.ECS88_4160,iECSF_1327.ECSF_3586,iECUMN_1333.ECUMN_4268,iEcSMS35_1347.EcSMS35_4106,iLF82_1304.LF82_0192,iNRG857_1313.NRG857_18615,iUMN146_1321.UM146_18880,iUMNK88_1353.UMNK88_4550,iUTI89_1310.UTI89_C4293,ic_1306.c4666 ATP-synt_A k141_15608_3 1042377.AFPJ01000012_gene1331 1.25e-45 147.0 COG0636@1|root,32S3K@2|Bacteria,1N1NA@1224|Proteobacteria,1S9MD@1236|Gammaproteobacteria,468H6@72275|Alteromonadaceae 1236|Gammaproteobacteria C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpE GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_C k141_15608_4 1453501.JELR01000002_gene1128 2.96e-53 172.0 COG0711@1|root,COG0711@2|Bacteria,1RHZ0@1224|Proteobacteria,1S402@1236|Gammaproteobacteria,4670M@72275|Alteromonadaceae 1236|Gammaproteobacteria C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) atpF GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031225,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - e_coli_core.b3736,iAF1260.b3736,iB21_1397.B21_03564,iBWG_1329.BWG_3427,iE2348C_1286.E2348C_4046,iEC042_1314.EC042_4123,iEC55989_1330.EC55989_4211,iECABU_c1320.ECABU_c42210,iECBD_1354.ECBD_4296,iECB_1328.ECB_03620,iECDH10B_1368.ECDH10B_3923,iECDH1ME8569_1439.ECDH1ME8569_3624,iECD_1391.ECD_03620,iECED1_1282.ECED1_4426,iECH74115_1262.ECH74115_5172,iECIAI1_1343.ECIAI1_3920,iECIAI39_1322.ECIAI39_4340,iECO103_1326.ECO103_4422,iECO111_1330.ECO111_4570,iECO26_1355.ECO26_4842,iECOK1_1307.ECOK1_4185,iECP_1309.ECP_3935,iECS88_1305.ECS88_4158,iECSE_1348.ECSE_4026,iECSF_1327.ECSF_3584,iECSP_1301.ECSP_4786,iECUMN_1333.ECUMN_4266,iECW_1372.ECW_m4039,iECs_1301.ECs4678,iEKO11_1354.EKO11_4609,iETEC_1333.ETEC_4027,iEcDH1_1363.EcDH1_4231,iEcE24377_1341.EcE24377A_4252,iEcHS_1320.EcHS_A3952,iEcSMS35_1347.EcSMS35_4104,iEcolC_1368.EcolC_4258,iG2583_1286.G2583_4532,iJO1366.b3736,iJR904.b3736,iSDY_1059.SDY_4012,iSFV_1184.SFV_3762,iSF_1195.SF3816,iSFxv_1172.SFxv_4159,iSSON_1240.SSON_3883,iS_1188.S3952,iSbBS512_1146.SbBS512_E4185,iUMN146_1321.UM146_18870,iUMNK88_1353.UMNK88_4548,iUTI89_1310.UTI89_C4291,iWFL_1372.ECW_m4039,iY75_1357.Y75_RS18390,iZ_1308.Z5234,ic_1306.c4664 ATP-synt_B k141_27425_1 1042377.AFPJ01000019_gene2533 6.48e-65 212.0 COG4242@1|root,COG4242@2|Bacteria,1PR9J@1224|Proteobacteria,1RVJH@1236|Gammaproteobacteria,469D6@72275|Alteromonadaceae 1236|Gammaproteobacteria PQ Peptidase family S51 cphB - 3.4.15.6 ko:K13282 - - R09722 RC00064,RC00141 ko00000,ko01000,ko01002 - - - Peptidase_S51 k141_2509_1 1042377.AFPJ01000032_gene2753 3.19e-63 199.0 COG0564@1|root,COG0564@2|Bacteria,1MVJ5@1224|Proteobacteria,1RN4N@1236|Gammaproteobacteria,4646S@72275|Alteromonadaceae 1236|Gammaproteobacteria J Responsible for synthesis of pseudouridine from uracil rluA - 5.4.99.28,5.4.99.29 ko:K06177 - - - - ko00000,ko01000,ko03009,ko03016 - - - PseudoU_synth_2 k141_7231_2 1116375.VEJY3_15275 8.79e-123 355.0 COG0169@1|root,COG0169@2|Bacteria,1MVH4@1224|Proteobacteria,1RPB7@1236|Gammaproteobacteria,1XTNJ@135623|Vibrionales 135623|Vibrionales E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) aroE GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000 - - - Shikimate_DH,Shikimate_dh_N k141_11990_1 1279017.AQYJ01000020_gene1226 6.55e-76 243.0 COG1273@1|root,COG1273@2|Bacteria,1MWCU@1224|Proteobacteria,1RYQ0@1236|Gammaproteobacteria,46705@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF3426) - - - - - - - - - - - - DUF3426,zinc_ribbon_4,zinc_ribbon_5 k141_22721_1 1492922.GY26_03470 2.26e-43 159.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1J4C5@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - CZB,HAMP,MCPsignal,PAS,PAS_3,PAS_9,sCache_2 k141_28680_1 218284.CCDN010000006_gene3653 2.38e-57 191.0 COG3595@1|root,COG3595@2|Bacteria,1TS90@1239|Firmicutes,4HDI6@91061|Bacilli,1ZC95@1386|Bacillus 91061|Bacilli S Putative adhesin yvlB - - - - - - - - - - - DUF4097 k141_10786_1 1462526.BN990_03954 6.65e-61 187.0 COG1695@1|root,COG1695@2|Bacteria,1V8K6@1239|Firmicutes,4HJY6@91061|Bacilli,4C6UC@84406|Virgibacillus 91061|Bacilli K Transcriptional regulator PadR-like family - - - - - - - - - - - - PadR k141_19132_2 997296.PB1_16649 1.87e-40 135.0 COG3027@1|root,COG3027@2|Bacteria,1VFZR@1239|Firmicutes,4HNRI@91061|Bacilli,1ZHZX@1386|Bacillus 91061|Bacilli D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division zapA - - ko:K09888 - - - - ko00000,ko03036 - - - ZapA k141_17988_2 218284.CCDN010000008_gene4173 1.77e-208 581.0 2C5HJ@1|root,2Z812@2|Bacteria,1TQQ6@1239|Firmicutes,4HA3F@91061|Bacilli,1ZCGB@1386|Bacillus 91061|Bacilli S Tetraprenyl-beta-curcumene synthase ytpB - 4.2.3.130 ko:K16188 - - R10009 RC02994 ko00000,ko01000 - - - DUF2600 k141_17988_3 218284.CCDN010000008_gene4172 6.19e-11 61.2 COG2267@1|root,COG2267@2|Bacteria,1UZ5S@1239|Firmicutes,4HEHP@91061|Bacilli,1ZBD1@1386|Bacillus 91061|Bacilli I Alpha beta hydrolase ytpA GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0008150,GO:0008152,GO:0016020,GO:0016298,GO:0016787,GO:0016788,GO:0044238,GO:0071704 3.1.1.5 ko:K01048 ko00564,map00564 - - - ko00000,ko00001,ko01000 - - - Hydrolase_4 k141_29819_1 1116375.VEJY3_16706 2.36e-156 444.0 COG2207@1|root,COG2207@2|Bacteria,1Q3UX@1224|Proteobacteria,1RS88@1236|Gammaproteobacteria,1XZK0@135623|Vibrionales 135623|Vibrionales K helix_turn_helix, arabinose operon control protein - - - ko:K04033 - - - - ko00000,ko03000 - - - HTH_18 k141_31049_1 218284.CCDN010000001_gene739 4.32e-54 183.0 COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,4HA1G@91061|Bacilli,1ZASC@1386|Bacillus 91061|Bacilli G COG0366 Glycosidases yugT - 3.2.1.10,3.2.1.20 ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00028,R00801,R00802,R01718,R01791,R06087,R06088,R06199 RC00028,RC00049,RC00059,RC00077,RC00451 ko00000,ko00001,ko01000 - GH13,GH31 iSB619.SA_RS07580 Alpha-amylase,Malt_amylase_C k141_36936_1 290512.Paes_0244 9.74e-70 236.0 COG0841@1|root,COG0841@2|Bacteria,1FDJ5@1090|Chlorobi 1090|Chlorobi V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran k141_15609_2 1294265.JCM21738_2676 2.86e-24 98.2 2EEB8@1|root,3385J@2|Bacteria,1VM15@1239|Firmicutes,4HPJI@91061|Bacilli,1ZJ91@1386|Bacillus 91061|Bacilli S Spore germination protein GerPE gerPE - - ko:K06303 - - - - ko00000 - - - GerPE k141_15609_4 218284.CCDN010000005_gene3234 9.91e-74 226.0 2EBJR@1|root,335K6@2|Bacteria,1VF1J@1239|Firmicutes,4HNKG@91061|Bacilli,1ZI2K@1386|Bacillus 91061|Bacilli S Spore germination protein gerPC - - ko:K06301 - - - - ko00000 - - - GerPC k141_21559_1 1294265.JCM21738_3536 4.67e-136 391.0 COG0667@1|root,COG0667@2|Bacteria,1TPIY@1239|Firmicutes,4HA4Q@91061|Bacilli,1ZCES@1386|Bacillus 91061|Bacilli C Aldo keto reductase - - - - - - - - - - - - Aldo_ket_red k141_19133_1 318996.AXAZ01000046_gene1512 1.31e-63 213.0 COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,2TRC2@28211|Alphaproteobacteria,3JR6K@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I Biotin carboxylase C-terminal domain MA20_22950 - 6.4.1.5 ko:K13777 ko00281,map00281 - R03494 RC00367,RC00942 ko00000,ko00001,ko01000 - - - Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2 k141_20294_1 324602.Caur_1155 6.24e-102 305.0 COG0601@1|root,COG0601@2|Bacteria,2G7KR@200795|Chloroflexi,3774H@32061|Chloroflexia 32061|Chloroflexia P PFAM binding-protein-dependent transport systems inner membrane component - - - ko:K02033 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 k141_17989_1 1294265.JCM21738_1133 1.89e-151 433.0 COG0626@1|root,COG0626@2|Bacteria,1TPC7@1239|Firmicutes,4HAFQ@91061|Bacilli,1ZAR9@1386|Bacillus 91061|Bacilli E cystathionine metC GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0016740,GO:0016765,GO:0016829,GO:0016846 4.4.1.8 ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU11880 Cys_Met_Meta_PP k141_17989_2 1294265.JCM21738_1132 4.99e-10 57.0 COG0626@1|root,COG0626@2|Bacteria,1TPC7@1239|Firmicutes,4HAFQ@91061|Bacilli,1ZAR9@1386|Bacillus 91061|Bacilli E cystathionine metB GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0016740,GO:0016765,GO:0016829,GO:0016846 2.5.1.48 ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017 R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946 RC00020,RC00056,RC00069,RC00420,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000 - - - Cys_Met_Meta_PP k141_160_3 1161401.ASJA01000019_gene1171 1.5e-19 85.1 2DSPA@1|root,33GWY@2|Bacteria,1NNRJ@1224|Proteobacteria,2VGIS@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_160_4 1569209.BBPH01000168_gene405 2.82e-24 105.0 COG0614@1|root,COG0614@2|Bacteria,1RAUP@1224|Proteobacteria,2TUB0@28211|Alphaproteobacteria,2PWC8@265|Paracoccus 28211|Alphaproteobacteria P Periplasmic binding protein - - - ko:K02016 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - Peripla_BP_2 k141_27427_1 1042377.AFPJ01000042_gene1096 3.14e-173 494.0 COG2274@1|root,COG2274@2|Bacteria,1R2T0@1224|Proteobacteria,1SBE1@1236|Gammaproteobacteria,465VB@72275|Alteromonadaceae 1236|Gammaproteobacteria V ABC transporter - - - ko:K12541,ko:K12542 ko02010,map02010 M00330 - - ko00000,ko00001,ko00002,ko02000,ko02044 3.A.1.109.3,3.A.1.109.4,8.A.1 - - ABC_membrane,ABC_tran,Peptidase_C39 k141_13232_2 218284.CCDN010000001_gene1095 6.57e-181 511.0 COG1304@1|root,COG1304@2|Bacteria,1TQZ3@1239|Firmicutes,4HAMV@91061|Bacilli,1ZCXC@1386|Bacillus 91061|Bacilli C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) fni GO:0003674,GO:0003824,GO:0004452,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016853,GO:0016860,GO:0016863,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0071704,GO:1901576 5.3.3.2 ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095,M00096,M00364,M00365,M00366,M00367 R01123 RC00455 ko00000,ko00001,ko00002,ko01000 - - - FMN_dh k141_14404_2 313612.L8106_28236 4.45e-101 306.0 2EZ0U@1|root,33S7B@2|Bacteria,1GCCF@1117|Cyanobacteria,1HEY3@1150|Oscillatoriales 1117|Cyanobacteria - - - - - - - - - - - - - - - k141_2512_1 521098.Aaci_0499 4.07e-86 277.0 COG2801@1|root,COG2801@2|Bacteria,1TT8V@1239|Firmicutes,4HCE5@91061|Bacilli,279CZ@186823|Alicyclobacillaceae 91061|Bacilli L PFAM Integrase catalytic region - - - - - - - - - - - - HTH_23,HTH_28,HTH_29,rve k141_1247_2 1279017.AQYJ01000029_gene3544 1.1e-271 757.0 COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,1RNB7@1236|Gammaproteobacteria,464KP@72275|Alteromonadaceae 1236|Gammaproteobacteria S metal-dependent hydrolase with the TIM-barrel fold - - - - - - - - - - - - Amidohydro_3 k141_35755_1 1279017.AQYJ01000029_gene3834 8.85e-214 592.0 COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,1RMEX@1236|Gammaproteobacteria,465FC@72275|Alteromonadaceae 1236|Gammaproteobacteria C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family trxB GO:0000166,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - iPC815.YPO1374 Pyr_redox_2 k141_35755_2 1279017.AQYJ01000029_gene3836 2.78e-111 344.0 COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,1RM9A@1236|Gammaproteobacteria,4647U@72275|Alteromonadaceae 1236|Gammaproteobacteria D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins ftsK GO:0000920,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006950,GO:0006970,GO:0007059,GO:0008094,GO:0008150,GO:0009628,GO:0009651,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0015616,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0033676,GO:0042221,GO:0042623,GO:0042802,GO:0043085,GO:0043565,GO:0044093,GO:0044425,GO:0044459,GO:0044464,GO:0045893,GO:0045935,GO:0046677,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051301,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0070887,GO:0071236,GO:0071944,GO:0080090,GO:0097159,GO:0140097,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma k141_31051_1 218284.CCDN010000002_gene2787 2.1e-39 142.0 COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,4H9SZ@91061|Bacilli,1ZAX7@1386|Bacillus 91061|Bacilli E Sodium alanine symporter agcS - - ko:K03310 - - - - ko00000 2.A.25 - - Na_Ala_symp k141_16737_1 945550.VISI1226_11157 6.27e-31 116.0 COG1494@1|root,COG1494@2|Bacteria,1MUB1@1224|Proteobacteria,1RR0E@1236|Gammaproteobacteria,1XTI1@135623|Vibrionales 135623|Vibrionales G COG1494 Fructose-1,6-bisphosphatase sedoheptulose 1,7-bisphosphatase and related proteins glpX - 3.1.3.11 ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 M00003,M00165,M00167 R00762,R04780 RC00017 ko00000,ko00001,ko00002,ko01000 - - - FBPase_glpX k141_16737_2 1116375.VEJY3_01230 2.54e-26 99.0 COG3074@1|root,COG3074@2|Bacteria,1MZJE@1224|Proteobacteria,1S8TG@1236|Gammaproteobacteria,1XYCG@135623|Vibrionales 135623|Vibrionales D Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA zapB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K09892 - - - - ko00000,ko03036 - - - ZapB k141_16737_3 1116375.VEJY3_01235 1.78e-107 311.0 COG0684@1|root,COG0684@2|Bacteria,1RH18@1224|Proteobacteria,1RS9U@1236|Gammaproteobacteria,1XVB5@135623|Vibrionales 135623|Vibrionales H Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome rraA - - ko:K02553 - - - - ko00000,ko03019 - - - RraA-like k141_16737_4 674977.VMC_04100 1.46e-191 535.0 COG1575@1|root,COG1575@2|Bacteria,1MXQQ@1224|Proteobacteria,1S58B@1236|Gammaproteobacteria,1Y2Q8@135623|Vibrionales 135623|Vibrionales H Belongs to the MenA family. Type 1 subfamily menA - 2.5.1.74 ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R05617,R06858,R10757 RC02935,RC02936,RC03264 ko00000,ko00001,ko00002,ko01000,ko01006 - - - UbiA k141_16737_5 223926.28805231 6.28e-306 835.0 COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,1RMYV@1236|Gammaproteobacteria,1XSGN@135623|Vibrionales 135623|Vibrionales O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis hslU GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564 - ko:K03667 - - - - ko00000,ko03110 - - - AAA_2,ClpB_D2-small k141_16737_7 1116375.VEJY3_01255 2.72e-108 313.0 COG3087@1|root,COG3087@2|Bacteria,1PWIT@1224|Proteobacteria,1RNC1@1236|Gammaproteobacteria,1XVV0@135623|Vibrionales 135623|Vibrionales D cell division protein ftsN - - ko:K03591 - - - - ko00000,ko03036 - - - SPOR k141_16737_8 1219076.N646_2444 9.46e-235 646.0 COG1609@1|root,COG1609@2|Bacteria,1MVUR@1224|Proteobacteria,1RN8T@1236|Gammaproteobacteria,1XTP1@135623|Vibrionales 135623|Vibrionales K transcriptional cytR - - ko:K05499 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 k141_16737_9 1219076.N646_2445 4.71e-21 91.3 COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,1RPZ7@1236|Gammaproteobacteria,1XT0R@135623|Vibrionales 135623|Vibrionales L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA priA - - ko:K04066 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C k141_9611_2 1279017.AQYJ01000019_gene1516 8.54e-198 551.0 COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,1RSE6@1236|Gammaproteobacteria,46691@72275|Alteromonadaceae 1236|Gammaproteobacteria M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamD GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - ko:K05807 - - - - ko00000,ko02000 1.B.33.1 - - YfiO k141_9611_3 1453501.JELR01000005_gene1787 1.87e-172 488.0 COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,1RN7F@1236|Gammaproteobacteria,4643F@72275|Alteromonadaceae 1236|Gammaproteobacteria J Responsible for synthesis of pseudouridine from uracil rluD GO:0000027,GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022607,GO:0022613,GO:0022618,GO:0031118,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 ko:K06180 - - - - ko00000,ko01000,ko03009 - - iE2348C_1286.E2348C_2868,iECED1_1282.ECED1_3035,iECSF_1327.ECSF_2432 PseudoU_synth_2,S4 k141_9611_4 1279017.AQYJ01000019_gene1518 2.98e-124 360.0 COG1496@1|root,COG1496@2|Bacteria,1MW2H@1224|Proteobacteria,1RNV4@1236|Gammaproteobacteria,466CB@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the multicopper oxidase YfiH RL5 family yfiH GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0016491,GO:0016679,GO:0016682,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0046983,GO:0055114 - ko:K05810 - - - - ko00000,ko01000 - - - Cu-oxidase_4 k141_3707_2 225937.HP15_2854 9.15e-18 81.6 2DRCR@1|root,33B8F@2|Bacteria,1NHMX@1224|Proteobacteria,1SHBQ@1236|Gammaproteobacteria,46BVX@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF4174) - - - - - - - - - - - - DUF4174 k141_21560_2 218284.CCDN010000002_gene2652 2.61e-115 335.0 COG2334@1|root,COG2334@2|Bacteria,1UZ9H@1239|Firmicutes,4HEG1@91061|Bacilli,1ZDST@1386|Bacillus 91061|Bacilli S Ecdysteroid kinase - - - - - - - - - - - - APH k141_15610_1 218284.CCDN010000001_gene1043 1.43e-70 214.0 COG1366@1|root,COG1366@2|Bacteria,1VENG@1239|Firmicutes,4HINR@91061|Bacilli,1ZGYC@1386|Bacillus 91061|Bacilli T Belongs to the anti-sigma-factor antagonist family spoIIAA - - ko:K06378 - - - - ko00000 - - - STAS k141_23861_1 1279017.AQYJ01000023_gene3101 0.0 1734.0 COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,1RND3@1236|Gammaproteobacteria,4658W@72275|Alteromonadaceae 1236|Gammaproteobacteria E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor gcvP GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019464,GO:0019752,GO:0032991,GO:0042133,GO:0042135,GO:0042737,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902494,GO:1990204 1.4.4.2 ko:K00281,ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko00002,ko01000 - - iECIAI39_1322.ECIAI39_3318 GDC-P k141_28706_1 768710.DesyoDRAFT_0633 1.23e-30 116.0 COG2323@1|root,COG2323@2|Bacteria,1UZYT@1239|Firmicutes,24GRN@186801|Clostridia,266Y2@186807|Peptococcaceae 186801|Clostridia S Protein of unknown function (DUF421) - - - - - - - - - - - - DUF421 k141_18015_1 981383.AEWH01000022_gene2530 4.1e-225 632.0 COG4584@1|root,COG4584@2|Bacteria,1TR5X@1239|Firmicutes,4H9QJ@91061|Bacilli 91061|Bacilli L Transposase - - - - - - - - - - - - HTH_23,HTH_38,HTH_7,rve k141_192_1 766499.C357_20707 1.07e-113 328.0 COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,2U5P0@28211|Alphaproteobacteria 28211|Alphaproteobacteria J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ctc GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02897 ko03010,map03010 M00178 - - ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L25p,Ribosomal_TL5_C k141_10799_2 1279017.AQYJ01000028_gene2434 1.24e-57 197.0 COG1506@1|root,COG1506@2|Bacteria,1P6E1@1224|Proteobacteria,1RPRK@1236|Gammaproteobacteria,464ZW@72275|Alteromonadaceae 1236|Gammaproteobacteria E Dipeptidyl peptidase IV (DPP IV) N-terminal region dpp4 - 3.4.14.5 ko:K01278 ko04974,map04974 - - - ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 - - - DPPIV_N,Peptidase_S9 k141_13245_1 218284.CCDN010000007_gene3789 4.4e-144 414.0 COG1195@1|root,COG1195@2|Bacteria,1TP9U@1239|Firmicutes,4HA0W@91061|Bacilli,1ZC8V@1386|Bacillus 91061|Bacilli L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP recF GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - ko:K03629 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - SMC_N k141_29834_1 218284.CCDN010000001_gene75 2.95e-142 404.0 COG1191@1|root,COG1191@2|Bacteria,1TPDD@1239|Firmicutes,4H9MN@91061|Bacilli,1ZB53@1386|Bacillus 91061|Bacilli K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released sigG - - ko:K03091 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r3,Sigma70_r4 k141_12014_1 218284.CCDN010000002_gene2870 5.61e-21 90.9 COG3290@1|root,COG3290@2|Bacteria,1TQJR@1239|Firmicutes,4H9Q0@91061|Bacilli,1ZBHV@1386|Bacillus 91061|Bacilli T Signal transduction histidine kinase regulating citrate malate metabolism citS - 2.7.13.3 ko:K11637 ko02020,map02020 M00487 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,PAS,PAS_8,PAS_9,SPOB_a,sCache_3_2 k141_26323_1 218284.CCDN010000002_gene2000 8e-202 575.0 COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,4HA1D@91061|Bacilli,1ZATN@1386|Bacillus 91061|Bacilli L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA ligA GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - - BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5 k141_6128_1 218284.CCDN010000002_gene2017 2.25e-107 325.0 COG3227@1|root,COG3227@2|Bacteria,1TP08@1239|Firmicutes,4H9S6@91061|Bacilli,1ZCEP@1386|Bacillus 91061|Bacilli E Peptidase M4 npr GO:0005575,GO:0005576 3.4.24.28 ko:K01400 - - - - ko00000,ko01000,ko01002 - - - FTP,PepSY,Peptidase_M4,Peptidase_M4_C k141_31078_1 1279017.AQYJ01000029_gene3475 8.44e-113 353.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,464D1@72275|Alteromonadaceae 1236|Gammaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K18138 ko01501,ko01503,map01501,map01503 M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2 - - ACR_tran k141_26324_1 1403313.AXBR01000005_gene1801 2e-50 169.0 COG0515@1|root,COG0515@2|Bacteria,1VBSJ@1239|Firmicutes,4HKRP@91061|Bacilli,1ZHE2@1386|Bacillus 91061|Bacilli KLT COG0515 Serine threonine protein kinase - - - - - - - - - - - - RIO1 k141_2535_1 1453501.JELR01000002_gene948 1.39e-86 259.0 COG3166@1|root,COG3166@2|Bacteria,1RF1S@1224|Proteobacteria,1S3S0@1236|Gammaproteobacteria,467DK@72275|Alteromonadaceae 1236|Gammaproteobacteria NU COG3166 Tfp pilus assembly protein PilN pilN - - ko:K02663 - - - - ko00000,ko02035,ko02044 - - - PilN k141_28707_1 1453501.JELR01000005_gene1590 8.13e-93 303.0 COG1520@1|root,COG2133@1|root,COG1520@2|Bacteria,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,1RNGN@1236|Gammaproteobacteria,465UX@72275|Alteromonadaceae 1236|Gammaproteobacteria G Glucose / Sorbosone dehydrogenase - - - - - - - - - - - - Big_2,CBM26,Cytochrome_CBB3,GSDH,PSCyt3,PSD2,PSD3,PSD4,PSD5 k141_14430_2 1279017.AQYJ01000020_gene1326 1.3e-175 498.0 COG1509@1|root,COG1509@2|Bacteria,1MUPJ@1224|Proteobacteria,1RM84@1236|Gammaproteobacteria,4651S@72275|Alteromonadaceae 1236|Gammaproteobacteria C Lysine 2,3-aminomutase YodO family protein epmB GO:0003674,GO:0003824,GO:0005488,GO:0016853,GO:0016866,GO:0016869,GO:0048037,GO:0051536,GO:0051539,GO:0051540 5.4.3.2 ko:K01843,ko:K19810 ko00310,map00310 - R00461 RC00303 ko00000,ko00001,ko01000,ko03012 - - iECH74115_1262.ECH74115_5662,iECIAI39_1322.ECIAI39_4611,iS_1188.S4569 Fer4_12,Fer4_14,Radical_SAM k141_9840_1 796606.BMMGA3_05930 8.91e-58 194.0 COG1461@1|root,COG1461@2|Bacteria,1TQMX@1239|Firmicutes,4HBSE@91061|Bacilli,1ZBRP@1386|Bacillus 91061|Bacilli S kinase related to dihydroxyacetone kinase yloV - - ko:K07030 - - - - ko00000 - - - Dak1_2,Dak2 k141_9840_2 218284.CCDN010000001_gene35 8.28e-42 139.0 COG1302@1|root,COG1302@2|Bacteria,1V731@1239|Firmicutes,4HIS4@91061|Bacilli,1ZG6I@1386|Bacillus 91061|Bacilli S protein conserved in bacteria yloU - - - - - - - - - - - Asp23 k141_8665_1 218284.CCDN010000001_gene1868 3.74e-172 486.0 COG1744@1|root,COG1744@2|Bacteria,1TPEU@1239|Firmicutes,4HANH@91061|Bacilli,1ZBS3@1386|Bacillus 91061|Bacilli S ABC-type transport system, periplasmic component surface lipoprotein tcsA - - ko:K02058,ko:K07335 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - Bmp k141_2739_1 42565.FP66_00625 7.36e-78 234.0 COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,1S3VN@1236|Gammaproteobacteria,1XJ83@135619|Oceanospirillales 135619|Oceanospirillales F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) purE - 5.4.99.18 ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07405 RC01947 ko00000,ko00001,ko00002,ko01000 - - - AIRC k141_29967_1 1078085.HMPREF1210_00665 2.03e-71 241.0 COG1409@1|root,COG4632@1|root,COG1409@2|Bacteria,COG4632@2|Bacteria,1UWQ2@1239|Firmicutes,4I2G2@91061|Bacilli,26G7J@186818|Planococcaceae 91061|Bacilli G Purple acid Phosphatase, N-terminal domain - - - - - - - - - - - - Metallophos,Pur_ac_phosph_N k141_24090_1 935836.JAEL01000026_gene4986 2.74e-86 268.0 COG3069@1|root,COG3069@2|Bacteria,1TQ99@1239|Firmicutes,4H9Q2@91061|Bacilli,1ZCNB@1386|Bacillus 91061|Bacilli C membrane yhfA - - - - - - - - - - - - k141_28892_1 1116375.VEJY3_14710 6.73e-202 565.0 COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,1RNS4@1236|Gammaproteobacteria,1XT9Q@135623|Vibrionales 135623|Vibrionales F Belongs to the GARS family purD GO:0003674,GO:0003824,GO:0004637,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.13 ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144 RC00090,RC00166 ko00000,ko00001,ko00002,ko01000 - - - GARS_A,GARS_C,GARS_N k141_28892_2 1116375.VEJY3_14715 6.22e-114 330.0 28HWS@1|root,2Z82N@2|Bacteria,1QFI0@1224|Proteobacteria,1RPY5@1236|Gammaproteobacteria,1XTX1@135623|Vibrionales 135623|Vibrionales M Protein of unknown function (DUF1481) atpB - - - - - - - - - - - DUF1481 k141_11020_1 218284.CCDN010000002_gene2888 1.23e-143 413.0 COG0609@1|root,COG0609@2|Bacteria,1TPX6@1239|Firmicutes,4HAM8@91061|Bacilli,1ZAU0@1386|Bacillus 91061|Bacilli P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily fhuG - - ko:K02015 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - FecCD k141_27591_1 1453501.JELR01000001_gene3217 3.05e-97 300.0 COG0515@1|root,COG0631@1|root,COG0515@2|Bacteria,COG0631@2|Bacteria,1MV1P@1224|Proteobacteria,1RNQN@1236|Gammaproteobacteria,464NH@72275|Alteromonadaceae 1236|Gammaproteobacteria T Serine threonine protein - - 3.1.3.16 ko:K01090,ko:K20074 - - - - ko00000,ko01000,ko01009 - - - PP2C_2,Pkinase k141_435_2 1279017.AQYJ01000025_gene722 7.96e-71 216.0 COG2050@1|root,COG2050@2|Bacteria,1N5HF@1224|Proteobacteria,1RNAK@1236|Gammaproteobacteria,46DIT@72275|Alteromonadaceae 1236|Gammaproteobacteria Q protein, possibly involved in aromatic compounds catabolism yigI GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - - - - - - - - - - 4HBT k141_7445_1 1294265.JCM21738_2878 4.63e-126 377.0 COG0768@1|root,COG0768@2|Bacteria,1TQHY@1239|Firmicutes,4HAFX@91061|Bacilli,1ZBJM@1386|Bacillus 91061|Bacilli M penicillin-binding protein pbpA - - ko:K21465 ko00550,map00550 - - - ko00000,ko00001,ko01011 - - - PBP_dimer,Transpeptidase k141_34802_1 1123371.ATXH01000004_gene1699 3.39e-119 357.0 COG0459@1|root,COG0459@2|Bacteria,2GHA6@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions groL - - ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 - - - Cpn60_TCP1 k141_9841_1 1453501.JELR01000002_gene930 7.91e-62 202.0 COG0860@1|root,COG0860@2|Bacteria,1MUQK@1224|Proteobacteria,1RMP1@1236|Gammaproteobacteria,4647N@72275|Alteromonadaceae 1236|Gammaproteobacteria M N-acetylmuramoyl-L-alanine amidase amiC - 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - AMIN,Amidase_3,LysM k141_436_1 42565.FP66_07750 1.67e-65 199.0 COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,1S3QE@1236|Gammaproteobacteria,1XK38@135619|Oceanospirillales 135619|Oceanospirillales FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hinT - - ko:K02503 - - - - ko00000,ko04147 - - - DcpS_C,HIT k141_436_2 42565.FP66_07755 2.34e-31 116.0 COG3954@1|root,COG3954@2|Bacteria,1MWN9@1224|Proteobacteria,1RMS7@1236|Gammaproteobacteria,1XHKN@135619|Oceanospirillales 135619|Oceanospirillales C Phosphoribulokinase - - 2.7.1.19 ko:K00855 ko00710,ko01100,ko01120,ko01200,map00710,map01100,map01120,map01200 M00165,M00166 R01523 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - PRK k141_22974_1 218284.CCDN010000001_gene596 3.48e-144 411.0 COG0834@1|root,COG0834@2|Bacteria,1UFZS@1239|Firmicutes,4HD9I@91061|Bacilli,1ZCBK@1386|Bacillus 91061|Bacilli ET Belongs to the bacterial solute-binding protein 3 family fliY - - ko:K02030,ko:K02424 ko02010,map02010 M00234,M00236 - - ko00000,ko00001,ko00002,ko02000,ko02035 3.A.1.3,3.A.1.3.10,3.A.1.3.14 - - SBP_bac_3 k141_37111_2 1453501.JELR01000001_gene1869 2.92e-83 248.0 COG0671@1|root,COG0671@2|Bacteria,1RJ1T@1224|Proteobacteria,1SAU1@1236|Gammaproteobacteria,466ER@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG0671 Membrane-associated phospholipid phosphatase - - 3.6.1.27 ko:K19302 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - PAP2 k141_18227_2 1294265.JCM21738_4151 2.72e-133 383.0 COG0566@1|root,COG0566@2|Bacteria,1TP9G@1239|Firmicutes,4HBBI@91061|Bacilli,1ZAXC@1386|Bacillus 91061|Bacilli J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family trmH GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 ko:K03218 - - - - ko00000,ko01000,ko03009 - - - SpoU_methylase,SpoU_sub_bind k141_11021_1 644282.Deba_1989 8.3e-06 51.6 COG4964@1|root,COG4964@2|Bacteria,1MV8G@1224|Proteobacteria,42PA6@68525|delta/epsilon subdivisions,2WIIY@28221|Deltaproteobacteria 28221|Deltaproteobacteria U Belongs to the GSP D family - - - ko:K02280 - - - - ko00000,ko02035,ko02044 - - - BON,Secretin,T2SS-T3SS_pil_N k141_11021_2 1267533.KB906738_gene2049 8.22e-20 89.7 COG3745@1|root,COG3745@2|Bacteria,3Y4HR@57723|Acidobacteria,2JJ9A@204432|Acidobacteriia 204432|Acidobacteriia U flp pilus assembly protein CpaB - - - ko:K02279 - - - - ko00000,ko02035,ko02044 - - - RcpC,SAF k141_20478_1 218284.CCDN010000001_gene1197 1.21e-155 438.0 COG0207@1|root,COG0207@2|Bacteria,1TSIR@1239|Firmicutes,4H9QS@91061|Bacilli,1ZAUT@1386|Bacillus 91061|Bacilli F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis thyA GO:0003674,GO:0003824,GO:0004799,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0032259,GO:0034641,GO:0034654,GO:0042083,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046385,GO:0046483,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 - - - Thymidylat_synt k141_13484_1 218284.CCDN010000006_gene3595 3.81e-94 285.0 COG1622@1|root,COG1622@2|Bacteria,1TPF6@1239|Firmicutes,4HA9J@91061|Bacilli,1ZB28@1386|Bacillus 91061|Bacilli C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I qoxA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009055,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015002,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0016491,GO:0016679,GO:0016682,GO:0017144,GO:0019637,GO:0019693,GO:0022857,GO:0022890,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1902600 1.10.3.12 ko:K02826 ko00190,ko01100,map00190,map01100 M00416 R09492 RC00819 ko00000,ko00001,ko00002,ko01000 3.D.4.1 - iSB619.SA_RS05175 COX2,COX2_TM k141_28893_1 218284.CCDN010000004_gene3035 2.03e-106 319.0 COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,4HA95@91061|Bacilli,1ZCW9@1386|Bacillus 91061|Bacilli E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids alr - 5.1.1.1,5.1.1.5 ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 - R00401 RC00285 ko00000,ko00001,ko01000,ko01011 - - - Ala_racemase_C,Ala_racemase_N k141_437_2 218284.CCDN010000004_gene3123 1.59e-28 105.0 COG1476@1|root,COG1476@2|Bacteria,1V8FS@1239|Firmicutes,4HICR@91061|Bacilli,1ZFY3@1386|Bacillus 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_3,HTH_31 k141_21744_1 42565.FP66_05540 2.16e-133 379.0 COG4665@1|root,COG4665@2|Bacteria,1RDPJ@1224|Proteobacteria,1SS78@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q Tripartite ATP-independent periplasmic transporters, DctQ component - - - - - - - - - - - - DctQ k141_12333_1 218284.CCDN010000005_gene3324 1.35e-309 855.0 COG4666@1|root,COG4666@2|Bacteria,1TP0V@1239|Firmicutes,4HC4B@91061|Bacilli,1ZAWZ@1386|Bacillus 91061|Bacilli S Tripartite ATP-independent periplasmic transporter, DctM component siaT_4 - - - - - - - - - - - DUF3394,DctM k141_13485_1 1078085.HMPREF1210_02160 2.83e-42 144.0 COG0546@1|root,COG0546@2|Bacteria,1V1FQ@1239|Firmicutes,4HDVJ@91061|Bacilli,26F3Y@186818|Planococcaceae 91061|Bacilli S HAD-hyrolase-like nt5e - 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 - R01334 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 k141_22975_2 218284.CCDN010000005_gene3463 5.82e-60 187.0 COG1813@1|root,COG1813@2|Bacteria,1V6X3@1239|Firmicutes,4HIY0@91061|Bacilli,1ZJ0M@1386|Bacillus 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_3 k141_24091_1 1453501.JELR01000001_gene2367 1.47e-213 607.0 COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,1RMSR@1236|Gammaproteobacteria,4646K@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the peptidase S41A family prc GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016787,GO:0019538,GO:0023052,GO:0030163,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - BAGE,DUF3340,PDZ,Peptidase_S41 k141_26667_1 1517416.IDAT_10025 1.69e-46 170.0 COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,1RU5N@1236|Gammaproteobacteria 1236|Gammaproteobacteria K COG0457 FOG TPR repeat - - - - - - - - - - - - Sulfotransfer_3,TPR_14,TPR_16,TPR_19,TPR_2,TPR_8 k141_1476_1 218284.CCDN010000008_gene4193 4.55e-112 329.0 COG0115@1|root,COG0115@2|Bacteria,1TPY2@1239|Firmicutes,4HAWW@91061|Bacilli,1ZBVX@1386|Bacillus 91061|Bacilli E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction dat GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016769,GO:0019478,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0046416,GO:0046437,GO:0047810,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.6.1.21 ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 - R01148,R01582,R02459,R02851,R02924,R05053 RC00006,RC00008,RC00025 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_4 k141_1476_2 218284.CCDN010000008_gene4192 2.91e-109 327.0 COG0624@1|root,COG0624@2|Bacteria,1TPEG@1239|Firmicutes,4HC14@91061|Bacilli,1ZBI2@1386|Bacillus 91061|Bacilli E Dipeptidase ytjP - 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20 k141_20479_1 1123261.AXDW01000024_gene2052 8.42e-54 186.0 COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,1MV3Z@1224|Proteobacteria,1RMAJ@1236|Gammaproteobacteria,1X5E9@135614|Xanthomonadales 135614|Xanthomonadales IM Cytidylyltransferase-like - - - - - - - - - - - - CTP_transf_like,PfkB k141_8669_1 1408473.JHXO01000009_gene3309 7.03e-59 197.0 COG0612@1|root,COG0612@2|Bacteria,4NIQM@976|Bacteroidetes 976|Bacteroidetes S Insulinase (Peptidase family M16) - - - - - - - - - - - - Peptidase_M16,Peptidase_M16_C k141_19338_1 1116375.VEJY3_02845 6.98e-18 82.0 COG1473@1|root,COG1473@2|Bacteria,1MUIV@1224|Proteobacteria,1RQAM@1236|Gammaproteobacteria,1XVA0@135623|Vibrionales 135623|Vibrionales S COG1473 Metal-dependent amidase aminoacylase carboxypeptidase - - 3.5.1.32 ko:K01451 ko00360,map00360 - R01424 RC00096,RC00162 ko00000,ko00001,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 k141_19338_2 1116375.VEJY3_02840 3.45e-84 260.0 COG0477@1|root,COG2814@2|Bacteria,1QTW0@1224|Proteobacteria 1224|Proteobacteria EGP Major Facilitator proP - - ko:K03762,ko:K08195 - - - - ko00000,ko02000 2.A.1.15,2.A.1.6.4 - iJN746.PP_2703 MFS_1,Sugar_tr k141_438_1 218284.CCDN010000006_gene3528 6.88e-164 471.0 COG0619@1|root,COG0619@2|Bacteria,1VBW7@1239|Firmicutes,4HB6S@91061|Bacilli,1ZS19@1386|Bacillus 91061|Bacilli P Spore gernimation protein GerA - - - - - - - - - - - - GerA k141_33618_1 218284.CCDN010000002_gene1995 1.14e-55 188.0 COG1001@1|root,COG1001@2|Bacteria,1TP84@1239|Firmicutes,4HAIR@91061|Bacilli,1ZAY2@1386|Bacillus 91061|Bacilli F adenine deaminase yerA GO:0003674,GO:0003824,GO:0006040,GO:0006044,GO:0006046,GO:0008150,GO:0008152,GO:0008448,GO:0009056,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0046348,GO:0071704,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901575 3.5.4.2 ko:K01486 ko00230,ko01100,map00230,map01100 - R01244 RC00477 ko00000,ko00001,ko01000 - - - Adenine_deam_C,Amidohydro_1 k141_33618_2 218284.CCDN010000002_gene1996 1.2e-55 182.0 COG1470@1|root,COG1470@2|Bacteria,1TRGE@1239|Firmicutes,4HBPI@91061|Bacilli,1ZB6W@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3048) C-terminal domain yerB - - - - - - - - - - - DUF3048,DUF3048_C k141_24092_1 1042377.AFPJ01000029_gene550 1.45e-95 283.0 COG2885@1|root,COG2885@2|Bacteria,1RIG3@1224|Proteobacteria,1S5WW@1236|Gammaproteobacteria,46CH4@72275|Alteromonadaceae 1236|Gammaproteobacteria M OmpA family - - - - - - - - - - - - DUF4398,OmpA k141_7446_1 1492737.FEM08_20770 1.57e-44 161.0 COG2911@1|root,COG2911@2|Bacteria,4NHAF@976|Bacteroidetes,1I5BI@117743|Flavobacteriia,2NVIG@237|Flavobacterium 976|Bacteroidetes S COG NOG10142 non supervised orthologous group - - - - - - - - - - - - Porin_2 k141_7446_2 1305737.JAFX01000001_gene2691 1.15e-34 129.0 COG2159@1|root,COG2159@2|Bacteria,4P1VU@976|Bacteroidetes 976|Bacteroidetes S Amidohydrolase - - - - - - - - - - - - Amidohydro_2 k141_12334_1 218284.CCDN010000001_gene656 3.33e-177 503.0 COG1055@1|root,COG1055@2|Bacteria,1TPNN@1239|Firmicutes,4HAIC@91061|Bacilli,1ZBBN@1386|Bacillus 91061|Bacilli P Membrane arsB_2 - - ko:K03893 - - - - ko00000,ko02000 2.A.45.1,3.A.4.1 - - CitMHS k141_31268_1 218284.CCDN010000001_gene1162 9.2e-158 449.0 COG0116@1|root,COG0116@2|Bacteria,1TP0X@1239|Firmicutes,4HBKY@91061|Bacilli,1ZBJB@1386|Bacillus 91061|Bacilli L Belongs to the methyltransferase superfamily ypsC GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 - ko:K07444 - - - - ko00000,ko01000 - - - THUMP,UPF0020 k141_13515_2 1123377.AUIV01000007_gene1304 1.81e-12 62.0 COG3205@1|root,COG3205@2|Bacteria,1N85D@1224|Proteobacteria,1SCCN@1236|Gammaproteobacteria,1X84M@135614|Xanthomonadales 135614|Xanthomonadales S Predicted membrane protein (DUF2061) - - - - - - - - - - - - DUF2061 k141_26698_1 861299.J421_3217 3.69e-177 521.0 COG0542@1|root,COG0542@2|Bacteria,1ZTBV@142182|Gemmatimonadetes 142182|Gemmatimonadetes O Clp amino terminal domain, pathogenicity island component - - - ko:K03696 ko01100,map01100 - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N,UVR k141_27602_1 1121929.KB898662_gene339 1.86e-59 186.0 COG0346@1|root,COG0346@2|Bacteria,1V6XU@1239|Firmicutes,4HIFI@91061|Bacilli 91061|Bacilli E COG0346 Lactoylglutathione lyase and related lyases ywkD - - ko:K08234 - - - - ko00000 - - - Glyoxalase k141_29985_1 1294265.JCM21738_937 4.28e-105 315.0 COG0508@1|root,COG0508@2|Bacteria,1TP3C@1239|Firmicutes,4HBVM@91061|Bacilli,1ZBCB@1386|Bacillus 91061|Bacilli C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) odhB - 2.3.1.61 ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R02570,R02571,R08549 RC00004,RC02727,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding k141_28911_1 666686.B1NLA3E_04635 4.3e-52 174.0 COG1131@1|root,COG1131@2|Bacteria,1TPMQ@1239|Firmicutes,4HA8K@91061|Bacilli,1ZAYW@1386|Bacillus 91061|Bacilli V COG1131 ABC-type multidrug transport system, ATPase component yfiL - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 k141_28911_2 1232410.KI421428_gene1056 3.39e-87 263.0 COG1235@1|root,COG1235@2|Bacteria,1RIT2@1224|Proteobacteria,42SFE@68525|delta/epsilon subdivisions,2WPTA@28221|Deltaproteobacteria,43UMZ@69541|Desulfuromonadales 28221|Deltaproteobacteria S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B_2 k141_9884_1 796606.BMMGA3_01350 5.02e-79 238.0 COG3091@1|root,COG3091@2|Bacteria,1V6NU@1239|Firmicutes,4HIHY@91061|Bacilli,1ZG8Y@1386|Bacillus 91061|Bacilli S Belongs to the SprT family ydcK - - ko:K03095 - - - - ko00000 - - - SprT-like,Zn_ribbon_SprT k141_15816_1 1279017.AQYJ01000027_gene1859 8.94e-59 191.0 COG0226@1|root,COG0226@2|Bacteria,1MUH9@1224|Proteobacteria,1RN9U@1236|Gammaproteobacteria,464BK@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0226 ABC-type phosphate transport system, periplasmic component pstS - - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - PBP_like_2 k141_15816_2 1042377.AFPJ01000005_gene2465 1.13e-35 132.0 COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,1RQXJ@1236|Gammaproteobacteria,464I5@72275|Alteromonadaceae 1236|Gammaproteobacteria P probably responsible for the translocation of the substrate across the membrane pstC - - ko:K02037 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1,DUF3708 k141_23006_1 218284.CCDN010000001_gene122 8.56e-189 529.0 COG0628@1|root,COG0628@2|Bacteria,1TSI9@1239|Firmicutes,4HB3Q@91061|Bacilli,1ZD70@1386|Bacillus 91061|Bacilli S AI-2E family transporter - - - - - - - - - - - - AI-2E_transport k141_24104_2 1453501.JELR01000001_gene2237 1.64e-156 453.0 COG0845@1|root,COG0845@2|Bacteria,1MX8W@1224|Proteobacteria,1RP9Q@1236|Gammaproteobacteria,466XV@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0845 Membrane-fusion protein - - - - - - - - - - - - HlyD_D23 k141_8708_1 1453501.JELR01000001_gene2248 4e-138 407.0 COG2871@1|root,COG3182@1|root,COG2871@2|Bacteria,COG3182@2|Bacteria,1QTUV@1224|Proteobacteria,1RNTI@1236|Gammaproteobacteria,464VZ@72275|Alteromonadaceae 1236|Gammaproteobacteria C 2Fe-2S iron-sulfur cluster binding domain - - - - - - - - - - - - FAD_binding_6,Fer2,NAD_binding_1,PepSY_TM k141_32352_1 1238450.VIBNISOn1_900016 1.54e-90 269.0 COG2249@1|root,COG2249@2|Bacteria,1RA5X@1224|Proteobacteria,1S3UT@1236|Gammaproteobacteria,1XWHN@135623|Vibrionales 135623|Vibrionales S NADPH-quinone reductase (modulator of drug activity B) - - - - - - - - - - - - Flavodoxin_2 k141_20505_1 1280001.BAOA01000021_gene715 4.67e-75 229.0 COG3637@1|root,COG3637@2|Bacteria,1NC11@1224|Proteobacteria,1SX0Q@1236|Gammaproteobacteria,1XWCI@135623|Vibrionales 135623|Vibrionales M Outer membrane protein beta-barrel domain - - - - - - - - - - - - OMP_b-brl k141_25328_3 1279017.AQYJ01000029_gene3335 5.22e-101 298.0 COG3571@1|root,COG3571@2|Bacteria,1RD20@1224|Proteobacteria,1S3Y4@1236|Gammaproteobacteria,466TR@72275|Alteromonadaceae 1236|Gammaproteobacteria S hydrolase of the alpha beta-hydrolase fold - - - ko:K07020 - - - - ko00000 - - - Abhydrolase_6,DLH k141_25328_4 1279017.AQYJ01000029_gene3336 1.17e-35 122.0 COG2329@1|root,COG2329@2|Bacteria,1N861@1224|Proteobacteria,1SC9H@1236|Gammaproteobacteria,468QF@72275|Alteromonadaceae 1236|Gammaproteobacteria S enzyme involved in biosynthesis of extracellular polysaccharides - - - - - - - - - - - - ABM k141_4014_1 883.DvMF_2582 8.73e-95 286.0 COG2376@1|root,COG2376@2|Bacteria,1MVSR@1224|Proteobacteria,42PGX@68525|delta/epsilon subdivisions,2WMGA@28221|Deltaproteobacteria,2M9PZ@213115|Desulfovibrionales 28221|Deltaproteobacteria G TIGRFAM dihydroxyacetone kinase, DhaK subunit dhaK - 2.7.1.121,2.7.1.28,2.7.1.29,4.6.1.15 ko:K00863,ko:K05878 ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622 M00344 R01011,R01012,R01059 RC00002,RC00015,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Dak1,Dak2 k141_9885_1 106648.BBLJ01000011_gene1115 1.08e-26 107.0 COG3878@1|root,COG3878@2|Bacteria,1RAYR@1224|Proteobacteria,1S3GY@1236|Gammaproteobacteria,3NJDB@468|Moraxellaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF1963) - - - - - - - - - - - - DUF1963 k141_28912_1 1111729.ATYV01000002_gene2019 1.84e-32 129.0 COG0285@1|root,COG0285@2|Bacteria,2GJP2@201174|Actinobacteria,22KQG@1653|Corynebacteriaceae 201174|Actinobacteria H Folylpolyglutamate synthase folC GO:0003674,GO:0003824,GO:0004326,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006761,GO:0006807,GO:0008150,GO:0008152,GO:0008841,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046452,GO:0046483,GO:0046900,GO:0046901,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv2447c Mur_ligase_C,Mur_ligase_M k141_33650_2 218284.CCDN010000001_gene1873 6.61e-121 359.0 COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,4HAAP@91061|Bacilli,1ZB4E@1386|Bacillus 91061|Bacilli S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay rnjB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 - ko:K12574 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - Lactamase_B,RMMBL k141_11069_1 1042377.AFPJ01000037_gene2902 2.84e-128 376.0 COG0743@1|root,COG0743@2|Bacteria,1MU4G@1224|Proteobacteria,1RNNW@1236|Gammaproteobacteria,464MG@72275|Alteromonadaceae 1236|Gammaproteobacteria I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) dxr GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05688 RC01452 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_1814,iECOK1_1307.ECOK1_0174,iECS88_1305.ECS88_0183,iUMN146_1321.UM146_23670,iUTI89_1310.UTI89_C0188 DXPR_C,DXP_redisom_C,DXP_reductoisom k141_11069_2 1279017.AQYJ01000026_gene339 0.000615 41.2 COG0575@1|root,COG0575@2|Bacteria,1MWSV@1224|Proteobacteria,1RQ6M@1236|Gammaproteobacteria,4651P@72275|Alteromonadaceae 1236|Gammaproteobacteria I Belongs to the CDS family cdsA GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_1596,iSDY_1059.SDY_0191 CTP_transf_1 k141_12355_1 1219076.N646_1655 2.95e-299 818.0 COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,1RNQA@1236|Gammaproteobacteria,1XSWV@135623|Vibrionales 135623|Vibrionales G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis eno GO:0003674,GO:0003824,GO:0004634,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 - - - Enolase_C,Enolase_N k141_12355_2 223926.28807572 0.0 1071.0 COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,1RM92@1236|Gammaproteobacteria,1XSS5@135623|Vibrionales 135623|Vibrionales F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates pyrG GO:0003674,GO:0003824,GO:0003883,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 - - - CTP_synth_N,GATase k141_12355_3 1116375.VEJY3_13225 5.46e-110 321.0 COG1694@1|root,COG3956@2|Bacteria,1MVKM@1224|Proteobacteria,1RNVU@1236|Gammaproteobacteria,1XVCP@135623|Vibrionales 135623|Vibrionales S Nucleoside triphosphate mazG - 3.6.1.9 ko:K04765 ko00230,ko00240,ko00760,ko00770,ko01100,map00230,map00240,map00760,map00770,map01100 - R00086,R00087,R00103,R00287,R00426,R00515,R00662,R00720,R03004,R03036,R11323 RC00002 ko00000,ko00001,ko01000 - - - MazG k141_29986_1 1294265.JCM21738_3964 2.59e-125 361.0 COG0345@1|root,COG0345@2|Bacteria,1UZ3D@1239|Firmicutes,4HCJ6@91061|Bacilli,1ZBFA@1386|Bacillus 91061|Bacilli E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline comER - - ko:K02239 - M00429 - - ko00000,ko00002,ko02044 - - - F420_oxidored,P5CR_dimer k141_15817_1 218284.CCDN010000001_gene667 2.9e-151 445.0 COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,4HBX7@91061|Bacilli,1ZBN6@1386|Bacillus 91061|Bacilli KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance relA GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5 ko:K00951 ko00230,map00230 - R00429 RC00002,RC00078 ko00000,ko00001,ko01000 - - iYO844.BSU27600 ACT_4,HD_4,RelA_SpoT,TGS k141_33651_1 218284.CCDN010000001_gene1284 2.05e-64 205.0 COG0134@1|root,COG0134@2|Bacteria,1TR94@1239|Firmicutes,4HDZQ@91061|Bacilli,1ZD63@1386|Bacillus 91061|Bacilli E Belongs to the TrpC family trpC GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48,5.3.1.24 ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03508,R03509 RC00944,RC00945 ko00000,ko00001,ko00002,ko01000 - - - IGPS k141_11070_1 218284.CCDN010000002_gene2646 3.58e-93 291.0 COG1762@1|root,COG3711@1|root,COG1762@2|Bacteria,COG3711@2|Bacteria,1TQT1@1239|Firmicutes,4H9N4@91061|Bacilli,1ZBCM@1386|Bacillus 91061|Bacilli GKT COG3711 Transcriptional antiterminator - - 2.7.1.194 ko:K02821 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 M00283,M00550 R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.7.1 - - HTH_11,Mga,PRD,PTS_EIIA_2,PTS_IIB k141_8709_2 1120985.AUMI01000014_gene860 4.26e-34 133.0 COG2177@1|root,COG2177@2|Bacteria,1TPND@1239|Firmicutes,4H36P@909932|Negativicutes 909932|Negativicutes D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation ftsX - - ko:K09811 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - FtsX k141_25331_1 1461580.CCAS010000076_gene4178 6.01e-132 389.0 COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,4HA2X@91061|Bacilli,1ZCFH@1386|Bacillus 91061|Bacilli F Belongs to the formate--tetrahydrofolate ligase family fhs GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.3 ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R00943 RC00026,RC00111 ko00000,ko00001,ko00002,ko01000 - - - FTHFS k141_11071_1 706587.Desti_1327 5.73e-52 175.0 COG0082@1|root,COG0082@2|Bacteria,1MU98@1224|Proteobacteria,42MF9@68525|delta/epsilon subdivisions,2WJ57@28221|Deltaproteobacteria,2MQCX@213462|Syntrophobacterales 28221|Deltaproteobacteria E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system aroC GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01714 RC00586 ko00000,ko00001,ko00002,ko01000 - - iAF987.Gmet_0976 Chorismate_synt k141_16998_1 745411.B3C1_10897 1.48e-27 110.0 COG3802@1|root,COG3802@2|Bacteria,1MYER@1224|Proteobacteria,1RNNM@1236|Gammaproteobacteria,1J9KA@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - - k141_24105_1 218284.CCDN010000001_gene1000 7.44e-66 213.0 COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,4HC50@91061|Bacilli,1ZQ98@1386|Bacillus 91061|Bacilli I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) yqjD GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016421,GO:0016874,GO:0016885,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0071704,GO:0072329,GO:1901575 2.1.3.15,6.4.1.3 ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 M00373,M00741 R01859 RC00097,RC00609 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans k141_24105_2 218284.CCDN010000001_gene999 1.47e-73 223.0 COG0346@1|root,COG0346@2|Bacteria,1V6SC@1239|Firmicutes,4HCP5@91061|Bacilli,1ZHE7@1386|Bacillus 91061|Bacilli E COG0346 Lactoylglutathione lyase and related lyases mce - 5.1.99.1 ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00373,M00375,M00376,M00741 R02765,R09979 RC00780,RC02739 ko00000,ko00001,ko00002,ko01000 - - - Glyoxalase_4 k141_19354_2 218284.CCDN010000011_gene4407 3.38e-111 338.0 COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4HBVV@91061|Bacilli,1ZB7Z@1386|Bacillus 91061|Bacilli S ABC transporter ydiF - - ko:K06158 - - - - ko00000,ko03012 - - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn k141_13516_2 1219076.N646_4050 5.2e-273 748.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RMMJ@1236|Gammaproteobacteria,1XSPG@135623|Vibrionales 135623|Vibrionales C COG1960 Acyl-CoA dehydrogenases - - 1.3.8.4 ko:K00253 ko00280,ko01100,map00280,map01100 M00036 R04095 RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_13516_3 1219076.N646_4051 3.04e-81 241.0 COG0789@1|root,COG0789@2|Bacteria,1RITY@1224|Proteobacteria,1S61S@1236|Gammaproteobacteria,1Y0RA@135623|Vibrionales 135623|Vibrionales K MerR, DNA binding - - - - - - - - - - - - MerR,MerR-DNA-bind k141_29987_1 1294265.JCM21738_4031 1.09e-119 358.0 COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,4H9VQ@91061|Bacilli,1ZBC0@1386|Bacillus 91061|Bacilli M stage V sporulation protein D spoVD - - ko:K08384 ko00550,map00550 - - - ko00000,ko00001,ko01011 - - - PASTA,PBP_dimer,Transpeptidase k141_8711_1 1453501.JELR01000002_gene1231 7.23e-74 222.0 COG2363@1|root,COG2363@2|Bacteria,1MZX3@1224|Proteobacteria,1SCNB@1236|Gammaproteobacteria,468G6@72275|Alteromonadaceae 1236|Gammaproteobacteria S small membrane protein ygdD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - DUF423 k141_4017_1 1196324.A374_16088 8.17e-08 58.2 COG0601@1|root,COG0601@2|Bacteria,1VCQ9@1239|Firmicutes,4HMZ6@91061|Bacilli 91061|Bacilli EP COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components - - - ko:K02033 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 k141_32353_1 1532557.JL37_27705 3.23e-09 56.2 COG2181@1|root,COG2181@2|Bacteria,1MXGZ@1224|Proteobacteria,2VK31@28216|Betaproteobacteria,3T2F8@506|Alcaligenaceae 28216|Betaproteobacteria C Nitrate reductase narI - 1.7.5.1 ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 M00529,M00530 R00798,R01106,R09497 RC02812 ko00000,ko00001,ko00002,ko01000 5.A.3.1 - - Nitrate_red_gam k141_32353_2 1121935.AQXX01000115_gene5015 1.4e-86 264.0 COG2180@1|root,COG2180@2|Bacteria,1MY4E@1224|Proteobacteria,1RQ23@1236|Gammaproteobacteria,1XJCX@135619|Oceanospirillales 135619|Oceanospirillales C Nitrate reductase delta subunit narJ - - ko:K00373 ko02020,map02020 - - - ko00000,ko00001 - - - Nitrate_red_del k141_32353_3 1279017.AQYJ01000027_gene1682 1.95e-38 140.0 COG1140@1|root,COG1140@2|Bacteria,1MW9Q@1224|Proteobacteria,1RNMJ@1236|Gammaproteobacteria,46653@72275|Alteromonadaceae 1236|Gammaproteobacteria C Nitrate reductase beta subunit narH GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009898,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0031235,GO:0032991,GO:0033554,GO:0042126,GO:0043436,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204,GO:2001057 1.7.5.1 ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 M00529,M00530,M00804 R00798,R01106,R09497 RC02812 ko00000,ko00001,ko00002,ko01000 5.A.3.1 - iEcE24377_1341.EcE24377A_1376,iEcolC_1368.EcolC_2189 Fer4_11,Nitr_red_bet_C k141_5410_1 1042377.AFPJ01000009_gene171 9.11e-113 332.0 COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,1RMWD@1236|Gammaproteobacteria,4650E@72275|Alteromonadaceae 1236|Gammaproteobacteria S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation mltG GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006807,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0030203,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0042597,GO:0043170,GO:0044425,GO:0044459,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901564 - ko:K07082 - - - - ko00000 - - - YceG k141_1658_1 318996.AXAZ01000055_gene6355 8.16e-27 115.0 COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2TQVN@28211|Alphaproteobacteria,3JTQ7@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T Adenylate and Guanylate cyclase catalytic domain - - - - - - - - - - - - AAA_16,DZR,Guanylate_cyc,SAM_1 k141_23255_1 1279017.AQYJ01000023_gene3274 1.45e-192 550.0 COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,1RP55@1236|Gammaproteobacteria,465RX@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1178 ABC-type Fe3 transport system, permease component - - - ko:K02011 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - BPD_transp_1 k141_23255_2 1279017.AQYJ01000023_gene3273 1.12e-199 558.0 COG1840@1|root,COG1840@2|Bacteria,1MUEG@1224|Proteobacteria,1RQ6Z@1236|Gammaproteobacteria,4645A@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1840 ABC-type Fe3 transport system, periplasmic component fbpA - - ko:K02012 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - SBP_bac_6 k141_23255_4 1279017.AQYJ01000023_gene3271 3.35e-28 104.0 COG5591@1|root,COG5591@2|Bacteria,1N7TH@1224|Proteobacteria,1SF7U@1236|Gammaproteobacteria,46BWG@72275|Alteromonadaceae 1236|Gammaproteobacteria S Peptidase propeptide and YPEB domain - - - - - - - - - - - - PepSY_2 k141_23255_6 1453501.JELR01000001_gene2883 9.29e-205 572.0 COG1363@1|root,COG1363@2|Bacteria,1MWQV@1224|Proteobacteria,1RRZY@1236|Gammaproteobacteria,464JK@72275|Alteromonadaceae 1236|Gammaproteobacteria G peptidase M42 - - - - - - - - - - - - Peptidase_M42 k141_12624_1 390235.PputW619_4529 7.44e-07 50.4 COG2207@1|root,COG2207@2|Bacteria,1RH01@1224|Proteobacteria 1224|Proteobacteria K Transcriptional regulator - - - - - - - - - - - - Arabinose_bd,HTH_18 k141_12643_2 1279017.AQYJ01000027_gene1999 7.17e-90 279.0 COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,1RMW3@1236|Gammaproteobacteria,463Y1@72275|Alteromonadaceae 1236|Gammaproteobacteria G Belongs to the pyruvate kinase family pykA GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016043,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - e_coli_core.b1854,iAF1260.b1854,iB21_1397.B21_01813,iBWG_1329.BWG_1668,iEC042_1314.EC042_2021,iECBD_1354.ECBD_1784,iECB_1328.ECB_01825,iECDH10B_1368.ECDH10B_1995,iECDH1ME8569_1439.ECDH1ME8569_1801,iECD_1391.ECD_01825,iECO103_1326.ECO103_2044,iECO111_1330.ECO111_2362,iECO26_1355.ECO26_2692,iECUMN_1333.ECUMN_2152,iETEC_1333.ETEC_1887,iEcDH1_1363.EcDH1_1786,iEcE24377_1341.EcE24377A_2084,iEcHS_1320.EcHS_A1947,iEcSMS35_1347.EcSMS35_1332,iEcolC_1368.EcolC_1778,iG2583_1286.G2583_2306,iJO1366.b1854,iJR904.b1854,iSBO_1134.SBO_1162,iSSON_1240.SSON_1294,iSbBS512_1146.SbBS512_E2130,iUMNK88_1353.UMNK88_2326,iY75_1357.Y75_RS09740 PK,PK_C k141_1678_1 319224.Sputcn32_0184 1.24e-12 65.1 28U15@1|root,2ZG7F@2|Bacteria,1P6NS@1224|Proteobacteria,1SVFY@1236|Gammaproteobacteria,2QDXP@267890|Shewanellaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_2891_2 1117647.M5M_11060 1.28e-74 239.0 COG3639@1|root,COG3639@2|Bacteria,1N3HU@1224|Proteobacteria,1RYH5@1236|Gammaproteobacteria,1J7WT@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P COG3639 ABC-type phosphate phosphonate transport system, permease component phnE - - ko:K02042 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - BPD_transp_1 k141_6555_1 223926.28807922 3.44e-237 660.0 COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,1RMWS@1236|Gammaproteobacteria,1XTI6@135623|Vibrionales 135623|Vibrionales F bifunctional purine biosynthesis protein purh purH GO:0003674,GO:0003824,GO:0004643,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 - - - AICARFT_IMPCHas,MGS k141_6555_3 223926.28807920 3.64e-84 249.0 COG0789@1|root,COG0789@2|Bacteria,1RGX6@1224|Proteobacteria,1SYIJ@1236|Gammaproteobacteria,1XXE8@135623|Vibrionales 135623|Vibrionales K transcriptional regulators zntR - - ko:K13638 - - - - ko00000,ko03000 - - - MerR,MerR-DNA-bind,MerR_1 k141_6555_4 223926.28807919 7.69e-187 539.0 COG3710@1|root,COG3710@2|Bacteria,1R52Q@1224|Proteobacteria,1RQY5@1236|Gammaproteobacteria,1XVDH@135623|Vibrionales 135623|Vibrionales K Transcriptional activator CadC cadC - - ko:K03765 - - - - ko00000,ko03000 - - - Trans_reg_C k141_7638_2 218284.CCDN010000001_gene1913 4.25e-222 617.0 COG1377@1|root,COG1377@2|Bacteria,1TPRP@1239|Firmicutes,4HB7Y@91061|Bacilli,1ZBSH@1386|Bacillus 91061|Bacilli N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin flhB - - ko:K02401 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - Bac_export_2 k141_7638_3 218284.CCDN010000001_gene1912 1.47e-159 466.0 COG1298@1|root,COG1298@2|Bacteria,1TQBM@1239|Firmicutes,4H9XU@91061|Bacilli,1ZBID@1386|Bacillus 91061|Bacilli N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin flhA - - ko:K02400 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 - - FHIPEP k141_24315_1 1403313.AXBR01000013_gene1247 1.29e-82 247.0 COG1376@1|root,COG1376@2|Bacteria,1V9XU@1239|Firmicutes,4HKDD@91061|Bacilli,1ZGIN@1386|Bacillus 91061|Bacilli S protein conserved in bacteria ykuD - - - - - - - - - - - LysM,YkuD k141_17191_1 1294265.JCM21738_2080 2.62e-76 229.0 COG4970@1|root,COG4970@2|Bacteria,1VBS8@1239|Firmicutes,4HKPK@91061|Bacilli,1ZJ1Q@1386|Bacillus 91061|Bacilli NU COG2165 Type II secretory pathway, pseudopilin PulG comGD - - ko:K02246 - M00429 - - ko00000,ko00002,ko02044 - - - N_methyl k141_35087_1 42565.FP66_14865 3.67e-152 434.0 COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,1RND5@1236|Gammaproteobacteria,1XHGC@135619|Oceanospirillales 135619|Oceanospirillales CH hydroxylase ubiF - - ko:K18800 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04987,R08768 RC00046 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_3 k141_37355_2 218284.CCDN010000008_gene4144 4.56e-47 159.0 COG0596@1|root,COG0596@2|Bacteria,1TS4C@1239|Firmicutes,4HB6G@91061|Bacilli,1ZAU9@1386|Bacillus 91061|Bacilli S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) menH GO:0003674,GO:0003824,GO:0016787 4.2.99.20 ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R08166 RC02148,RC02475 ko00000,ko00001,ko00002,ko01000 - - - Abhydrolase_1 k141_29061_1 1279017.AQYJ01000025_gene684 2.05e-119 348.0 COG2227@1|root,COG2227@2|Bacteria,1MY0S@1224|Proteobacteria,1RP69@1236|Gammaproteobacteria,466U7@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs cmoM GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097697,GO:0140098,GO:0140101,GO:1901360 - ko:K06219 - - - - ko00000 - - - Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31 k141_29061_2 1265313.HRUBRA_00039 3.23e-14 71.2 COG2214@1|root,COG2214@2|Bacteria,1PUS9@1224|Proteobacteria,1S3X9@1236|Gammaproteobacteria 1236|Gammaproteobacteria O DnaJ-class molecular chaperone - - - - - - - - - - - - DnaJ k141_2892_1 1042377.AFPJ01000007_gene1819 1.22e-101 298.0 COG1309@1|root,COG1309@2|Bacteria,1N659@1224|Proteobacteria,1RPXN@1236|Gammaproteobacteria,4682Q@72275|Alteromonadaceae 1236|Gammaproteobacteria K MAATS-type transcriptional repressor, C-terminal region acrR GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042493,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0045892,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K03577 - M00647 - - ko00000,ko00002,ko03000 - - - TetR_C_2,TetR_N k141_26973_1 313606.M23134_06682 1.39e-22 94.7 2CHNQ@1|root,2Z7KM@2|Bacteria,4NHAA@976|Bacteroidetes,47U34@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - k141_26973_2 1042377.AFPJ01000028_gene2222 2.86e-174 495.0 COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,1RNGN@1236|Gammaproteobacteria,464U6@72275|Alteromonadaceae 1236|Gammaproteobacteria G COG2133 Glucose sorbosone dehydrogenases - - - ko:K21430 - - - - ko00000,ko01000 - - - Cytochrome_CBB3,GSDH k141_718_1 218284.CCDN010000001_gene805 4.85e-173 488.0 COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,4HBAU@91061|Bacilli,1ZBV8@1386|Bacillus 91061|Bacilli G Glucokinase glcK GO:0003674,GO:0003824,GO:0004340,GO:0004396,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044464,GO:0046835,GO:0051156,GO:0071704,GO:1901135 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS07790 ROK k141_13832_1 1453501.JELR01000001_gene2098 4.97e-132 379.0 COG0564@1|root,COG0564@2|Bacteria,1N8GW@1224|Proteobacteria,1RMZ7@1236|Gammaproteobacteria,466SC@72275|Alteromonadaceae 1236|Gammaproteobacteria J COG0564 Pseudouridylate synthases, 23S RNA-specific truC GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.26 ko:K06175 - - - - ko00000,ko01000,ko03016 - - - PseudoU_synth_2 k141_13832_2 926566.Terro_1461 1.42e-76 256.0 COG2609@1|root,COG2609@2|Bacteria,3Y2M3@57723|Acidobacteria,2JHM5@204432|Acidobacteriia 204432|Acidobacteriia C Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) - - 1.2.4.1 ko:K00163 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - Transketolase_N k141_6556_1 218284.CCDN010000003_gene2989 1.86e-193 570.0 COG1197@1|root,COG1197@2|Bacteria,1TPF1@1239|Firmicutes,4H9NB@91061|Bacilli,1ZBAK@1386|Bacillus 91061|Bacilli L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd - - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF k141_12644_1 1410625.JHWK01000012_gene2081 0.00071 42.0 COG2199@1|root,COG3706@2|Bacteria,1UYBD@1239|Firmicutes,25FYT@186801|Clostridia,27UKW@186928|unclassified Lachnospiraceae 186801|Clostridia T diguanylate cyclase - - - - - - - - - - - - GGDEF k141_12644_2 218284.CCDN010000008_gene4252 7.93e-120 351.0 COG0626@1|root,COG0626@2|Bacteria,1TPC7@1239|Firmicutes,4IS7E@91061|Bacilli,1ZS1S@1386|Bacillus 91061|Bacilli E methionine gamma-lyase megL - 4.4.1.11 ko:K01761 ko00270,ko00450,map00270,map00450 - R00654,R04770 RC00196,RC00348,RC01209,RC01210 ko00000,ko00001,ko01000 - - - Cys_Met_Meta_PP k141_1680_1 1265503.KB905163_gene2331 5.89e-11 68.2 COG0845@1|root,COG0845@2|Bacteria,1MVFN@1224|Proteobacteria,1RNN6@1236|Gammaproteobacteria,2Q5NP@267889|Colwelliaceae 1236|Gammaproteobacteria M Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - ko:K18990 - M00720 - - ko00000,ko00002,ko02000 2.A.6.2.30,8.A.1 - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 k141_16013_1 1294265.JCM21738_4956 2.55e-200 572.0 COG1554@1|root,COG1554@2|Bacteria,1TQMB@1239|Firmicutes,4HAVB@91061|Bacilli,1ZBSM@1386|Bacillus 91061|Bacilli G Glycoside hydrolase, family 65 mapA GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0016787,GO:0030312,GO:0044464,GO:0071944 2.4.1.8 ko:K00691 ko00500,ko01100,map00500,map01100 - R01555 RC00049 ko00000,ko00001,ko01000 - GH65 - Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m k141_20730_2 218284.CCDN010000001_gene1756 7.25e-54 175.0 COG1443@1|root,COG1443@2|Bacteria,1V6SB@1239|Firmicutes,4HJ2T@91061|Bacilli,1ZFNY@1386|Bacillus 91061|Bacilli I COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes M1-740 - - - - - - - - - - - NUDIX k141_8978_2 218284.CCDN010000001_gene1101 1.3e-88 271.0 COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,4HAJ6@91061|Bacilli,1ZAUP@1386|Bacillus 91061|Bacilli S GTPase that plays an essential role in the late steps of ribosome biogenesis der - - ko:K03977 - - - - ko00000,ko03009 - - - KH_dom-like,MMR_HSR1 k141_25655_1 218284.CCDN010000001_gene971 1.63e-165 478.0 COG1154@1|root,COG1154@2|Bacteria,1TP37@1239|Firmicutes,4H9QW@91061|Bacilli,1ZBHF@1386|Bacillus 91061|Bacilli H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) dxs - 2.2.1.7 ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 M00096 R05636 RC00032 ko00000,ko00001,ko00002,ko01000 - - - DXP_synthase_N,Transket_pyr,Transketolase_C k141_13833_1 1123228.AUIH01000008_gene2414 3.64e-103 310.0 COG2224@1|root,COG2224@2|Bacteria,1MWIF@1224|Proteobacteria,1RQAK@1236|Gammaproteobacteria,1XI4D@135619|Oceanospirillales 135619|Oceanospirillales C Phosphoenolpyruvate phosphomutase - - 4.1.3.1 ko:K01637 ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200 M00012 R00479 RC00311,RC00313 ko00000,ko00001,ko00002,ko01000 - - - ICL k141_36123_1 935836.JAEL01000029_gene3574 2.94e-24 102.0 COG0075@1|root,COG3916@1|root,COG0075@2|Bacteria,COG3916@2|Bacteria,1TR3I@1239|Firmicutes,4HA6W@91061|Bacilli,1ZAT2@1386|Bacillus 91061|Bacilli E Aminotransferase class-V - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10,Acetyltransf_5,Acetyltransf_9,Aminotran_5 k141_36123_2 935836.JAEL01000029_gene3575 7.22e-27 110.0 COG1368@1|root,COG1368@2|Bacteria,1TRMA@1239|Firmicutes,4HFA5@91061|Bacilli,1ZDG2@1386|Bacillus 91061|Bacilli M Sulfatase - - - - - - - - - - - - Sulfatase k141_26975_2 218284.CCDN010000001_gene559 5.82e-09 55.8 COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HA2G@91061|Bacilli,1ZAY1@1386|Bacillus 91061|Bacilli IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II lcfA - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding,AMP-binding_C k141_23257_1 223926.28809862 2.84e-63 201.0 COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,1RQXJ@1236|Gammaproteobacteria,1XSNI@135623|Vibrionales 135623|Vibrionales P probably responsible for the translocation of the substrate across the membrane pstC - - ko:K02037 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 k141_23257_2 1116375.VEJY3_23336 2.26e-179 501.0 COG0226@1|root,COG0226@2|Bacteria,1RD2K@1224|Proteobacteria,1T0KP@1236|Gammaproteobacteria,1XUIY@135623|Vibrionales 135623|Vibrionales P ABC-type phosphate transport system, periplasmic component pstS - - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - PBP_like_2 k141_23257_3 1116375.VEJY3_23341 6.07e-218 621.0 COG0840@1|root,COG0840@2|Bacteria,1Q74R@1224|Proteobacteria,1RZUU@1236|Gammaproteobacteria,1XUYI@135623|Vibrionales 135623|Vibrionales NT methyl-accepting chemotaxis protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal k141_23257_4 1116375.VEJY3_23346 2.4e-302 828.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1XUCT@135623|Vibrionales 135623|Vibrionales L Belongs to the DEAD box helicase family - - - - - - - - - - - - DEAD,Helicase_C k141_23257_5 1116375.VEJY3_23351 3.69e-24 93.6 COG4238@1|root,COG4238@2|Bacteria,1MZCW@1224|Proteobacteria,1S8YB@1236|Gammaproteobacteria,1XYBW@135623|Vibrionales 135623|Vibrionales M Outer membrane lipoprotein lpp - - ko:K06078 - - - - ko00000,ko01011 - - - LPP k141_23257_6 223926.28809872 6.28e-199 553.0 COG1376@1|root,COG1376@2|Bacteria,1MVYT@1224|Proteobacteria,1RMNC@1236|Gammaproteobacteria,1XT0M@135623|Vibrionales 135623|Vibrionales M protein conserved in bacteria - - - ko:K16291,ko:K19236 ko01503,map01503 - - - ko00000,ko00001,ko01002,ko01011 - - - LysM,YkuD k141_23257_7 1116375.VEJY3_23361 0.0 869.0 COG0415@1|root,COG0415@2|Bacteria,1MV9Y@1224|Proteobacteria,1RNGJ@1236|Gammaproteobacteria,1XUEN@135623|Vibrionales 135623|Vibrionales H Belongs to the DNA photolyase family phrB GO:0003674,GO:0003824,GO:0003904,GO:0003913,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 4.1.99.3 ko:K01669 - - - - ko00000,ko01000,ko03400 - - - DNA_photolyase,FAD_binding_7 k141_23257_8 223926.28809874 1.71e-149 425.0 COG0789@1|root,COG0789@2|Bacteria,1R9SN@1224|Proteobacteria,1S967@1236|Gammaproteobacteria,1XUT1@135623|Vibrionales 135623|Vibrionales K Transcriptional regulator MerR family - - - ko:K22491 - - - - ko00000,ko03000 - - - MerR_1 k141_23257_9 1116375.VEJY3_23371 2.09e-217 601.0 COG1683@1|root,COG3272@1|root,COG1683@2|Bacteria,COG3272@2|Bacteria,1MXYZ@1224|Proteobacteria,1RNMF@1236|Gammaproteobacteria,1XUJK@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF1722) - - - - - - - - - - - - DUF1722,DUF523 k141_23257_10 1280001.BAOA01000076_gene3256 1.01e-159 448.0 COG0813@1|root,COG0813@2|Bacteria,1MUW6@1224|Proteobacteria,1RMMA@1236|Gammaproteobacteria,1XT8Y@135623|Vibrionales 135623|Vibrionales F phosphorylase deoD2 GO:0003674,GO:0003824,GO:0004731,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0034641,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:1901360 2.4.2.1 ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244 RC00033,RC00063,RC00122 ko00000,ko00001,ko01000 - - - PNP_UDP_1 k141_23257_11 1116375.VEJY3_23381 0.0 967.0 COG3677@1|root,COG3677@2|Bacteria,1R3VM@1224|Proteobacteria,1RS4K@1236|Gammaproteobacteria,1XUAR@135623|Vibrionales 135623|Vibrionales L COG3677 Transposase and inactivated derivatives - - - - - - - - - - - - - k141_23257_12 223926.28809879 3.46e-287 793.0 COG0457@1|root,COG0457@2|Bacteria,1NFT4@1224|Proteobacteria,1SPMW@1236|Gammaproteobacteria,1XSHX@135623|Vibrionales 135623|Vibrionales S COG0457 FOG TPR repeat - - - - - - - - - - - - - k141_23257_13 223926.28809880 5.64e-294 812.0 COG0457@1|root,COG2199@1|root,COG0457@2|Bacteria,COG3706@2|Bacteria,1NC00@1224|Proteobacteria,1SNFZ@1236|Gammaproteobacteria,1XSA5@135623|Vibrionales 135623|Vibrionales T COG2199 FOG GGDEF domain - - - - - - - - - - - - GGDEF k141_29062_1 1453501.JELR01000002_gene1533 1.9e-108 330.0 COG0038@1|root,COG0038@2|Bacteria,1MV4K@1224|Proteobacteria,1RQJW@1236|Gammaproteobacteria,465J9@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0038 Chloride channel protein EriC eriC - - ko:K03281 - - - - ko00000 2.A.49 - - Voltage_CLC k141_35088_1 1042377.AFPJ01000054_gene1715 5.58e-170 493.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1MUJ3@1224|Proteobacteria,1RRN4@1236|Gammaproteobacteria,4674P@72275|Alteromonadaceae 1236|Gammaproteobacteria EU Prolyl oligopeptidase, N-terminal beta-propeller domain - - - - - - - - - - - - PD40,Peptidase_S9,Peptidase_S9_N k141_35088_2 1453501.JELR01000002_gene985 1.55e-73 228.0 COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,1RNQK@1236|Gammaproteobacteria,466CZ@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline proC GO:0003674,GO:0003824,GO:0004735,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0017144,GO:0018130,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0055114,GO:0055129,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 - - iSBO_1134.SBO_0282,ic_1306.c0493 F420_oxidored,P5CR_dimer k141_33887_1 1279017.AQYJ01000022_gene2750 9.12e-79 242.0 COG0584@1|root,COG0584@2|Bacteria 2|Bacteria C glycerophosphodiester phosphodiesterase activity - - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - GDPD k141_33887_3 1453501.JELR01000002_gene245 3.17e-85 259.0 COG3121@1|root,COG3121@2|Bacteria,1NAG3@1224|Proteobacteria,1SCT1@1236|Gammaproteobacteria 1236|Gammaproteobacteria NU Pili and flagellar-assembly chaperone, PapD N-terminal domain - - - - - - - - - - - - PapD_N k141_24318_1 218284.CCDN010000002_gene2124 2.04e-105 307.0 COG0066@1|root,COG0066@2|Bacteria,1V1I6@1239|Firmicutes,4HFTY@91061|Bacilli,1ZAVC@1386|Bacillus 91061|Bacilli E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate leuD - 4.2.1.33,4.2.1.35 ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R10170 RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase_C k141_11391_1 1234664.AMRO01000027_gene1377 7.06e-26 97.1 2E6WR@1|root,331G7@2|Bacteria,1VHCS@1239|Firmicutes,4HQVN@91061|Bacilli,1WGUF@129337|Geobacillus 91061|Bacilli S Protein of unknown function (DUF2536) yrzA - - - - - - - - - - - DUF2536 k141_37358_1 1453501.JELR01000005_gene1780 2.57e-41 142.0 COG4726@1|root,COG4726@2|Bacteria,1N7KP@1224|Proteobacteria,1SCM5@1236|Gammaproteobacteria,46970@72275|Alteromonadaceae 1236|Gammaproteobacteria NU PilX N-terminal pilX - - ko:K02673 - - - - ko00000,ko02035,ko02044 - - - PilX,PilX_N k141_37358_2 1209072.ALBT01000033_gene1723 4.96e-40 145.0 COG4966@1|root,COG4966@2|Bacteria,1R5YK@1224|Proteobacteria,1RZIZ@1236|Gammaproteobacteria,1FHH9@10|Cellvibrio 1236|Gammaproteobacteria NU Type IV Pilus-assembly protein W pilW - - ko:K02672 - - - - ko00000,ko02035,ko02044 - - - N_methyl,PilW k141_23258_1 1246445.ANAY01000003_gene3148 2.2e-06 50.8 COG1028@1|root,COG1028@2|Bacteria,2I8MZ@201174|Actinobacteria 201174|Actinobacteria IQ Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis fabG - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 k141_25656_1 218284.CCDN010000007_gene3786 2.95e-97 309.0 COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,4HAHY@91061|Bacilli,1ZB8F@1386|Bacillus 91061|Bacilli L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrA - 5.99.1.3 ko:K02469 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseA_C,DNA_topoisoIV k141_25656_2 218284.CCDN010000007_gene3785 5.52e-05 44.3 COG2206@1|root,COG2206@2|Bacteria,1TR95@1239|Firmicutes,4HB8S@91061|Bacilli,1ZCD6@1386|Bacillus 91061|Bacilli T HD domain M1-161 - - - - - - - - - - - HD,HD_5 k141_29063_1 1121943.KB899995_gene731 2.75e-31 111.0 2C5EI@1|root,2ZXMM@2|Bacteria,1P7BC@1224|Proteobacteria,1SVT3@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_27767_1 1453501.JELR01000002_gene682 2.78e-117 347.0 COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,1RQR7@1236|Gammaproteobacteria,4668G@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria ycbB GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0006508,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0008236,GO:0008238,GO:0009273,GO:0009987,GO:0016740,GO:0016746,GO:0016755,GO:0016787,GO:0016807,GO:0017171,GO:0019538,GO:0033554,GO:0042546,GO:0043164,GO:0043170,GO:0044036,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0050896,GO:0051716,GO:0070004,GO:0070008,GO:0070011,GO:0071554,GO:0071704,GO:0071840,GO:0071972,GO:0140096,GO:1901564 - ko:K21470 - - - - ko00000,ko01002,ko01011 - - - PG_binding_1,YkuD k141_16039_1 42565.FP66_01725 1.68e-120 361.0 COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,1RMP2@1236|Gammaproteobacteria,1XHCR@135619|Oceanospirillales 135619|Oceanospirillales EG Belongs to the IlvD Edd family ilvD - 4.2.1.9 ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R01209,R04441,R05070 RC00468,RC01714 ko00000,ko00001,ko00002,ko01000 - - - ILVD_EDD k141_2909_1 935836.JAEL01000024_gene2430 6.91e-80 240.0 COG4917@1|root,COG4917@2|Bacteria,1VAYC@1239|Firmicutes,4HK7N@91061|Bacilli,1ZFJ5@1386|Bacillus 91061|Bacilli E Ethanolamine utilisation - propanediol utilisation - - - ko:K04029 - - - - ko00000 - - - PduV-EutP k141_12669_1 218284.CCDN010000001_gene722 6.23e-84 250.0 COG2131@1|root,COG2131@2|Bacteria,1V3PU@1239|Firmicutes,4HCDG@91061|Bacilli,1ZBGM@1386|Bacillus 91061|Bacilli F COG2131 Deoxycytidylate deaminase comEB - 3.5.4.12 ko:K01493 ko00240,ko01100,map00240,map01100 M00429 R01663 RC00074 ko00000,ko00001,ko00002,ko01000,ko02044 - - - dCMP_cyt_deam_1 k141_11420_1 1294265.JCM21738_5247 1.33e-87 273.0 COG1293@1|root,COG1293@2|Bacteria,1TQ8A@1239|Firmicutes,4H9UF@91061|Bacilli,1ZBGD@1386|Bacillus 91061|Bacilli K RNA-binding protein homologous to eukaryotic snRNP FbpA - - - - - - - - - - - DUF814,FbpA k141_29079_1 1279017.AQYJ01000023_gene3092 1.91e-130 394.0 COG0620@1|root,COG0620@2|Bacteria,1MUI9@1224|Proteobacteria,1RMBA@1236|Gammaproteobacteria,465YA@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation metE GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0032259,GO:0034641,GO:0035999,GO:0036211,GO:0042084,GO:0042085,GO:0042558,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0050667,GO:0051186,GO:0071704,GO:0140096,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - iE2348C_1286.E2348C_4130,iECO103_1326.ECO103_4334,iECO111_1330.ECO111_4657,iECO26_1355.ECO26_4756,iECW_1372.ECW_m4131,iEKO11_1354.EKO11_4528,iPC815.YPO3788,iWFL_1372.ECW_m4131 Meth_synt_1,Meth_synt_2 k141_17202_1 997296.PB1_01620 1.26e-91 269.0 COG2001@1|root,COG2001@2|Bacteria,1V3JD@1239|Firmicutes,4HH23@91061|Bacilli,1ZFN0@1386|Bacillus 91061|Bacilli K Belongs to the MraZ family mraZ GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - ko:K03925 - - - - ko00000 - - - MraZ k141_17202_2 1294265.JCM21738_4027 2.27e-51 170.0 COG0275@1|root,COG0275@2|Bacteria,1TNZV@1239|Firmicutes,4H9U2@91061|Bacilli,1ZCHN@1386|Bacillus 91061|Bacilli J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA rsmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 ko:K03438 - - - - ko00000,ko01000,ko03009 - - - Methyltransf_5 k141_25690_1 936136.ARRT01000003_gene6173 6.64e-55 181.0 COG0395@1|root,COG0395@2|Bacteria,1MUWS@1224|Proteobacteria,2TSYA@28211|Alphaproteobacteria,4BMAQ@82115|Rhizobiaceae 28211|Alphaproteobacteria G Binding-protein-dependent transport system inner membrane component - - - ko:K02026 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - BPD_transp_1 k141_35133_1 1453501.JELR01000002_gene379 8.62e-102 313.0 COG3291@1|root,COG3291@2|Bacteria 2|Bacteria S metallopeptidase activity - - 3.2.1.78 ko:K01218 ko00051,ko02024,map00051,map02024 - R01332 RC00467 ko00000,ko00001,ko01000 - GH26 - Alginate_lyase2,F5_F8_type_C,Laminin_G_3,PKD k141_10253_1 1453501.JELR01000002_gene894 2.72e-104 322.0 COG3501@1|root,COG3501@2|Bacteria,1MU7Q@1224|Proteobacteria,1RMZS@1236|Gammaproteobacteria,465CI@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria vgrG - - ko:K11904 ko03070,map03070 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - Gp5_C,Phage_GPD k141_33900_1 319224.Sputcn32_2046 8.93e-26 105.0 COG3386@1|root,COG3386@2|Bacteria,1MWTR@1224|Proteobacteria,1RSKQ@1236|Gammaproteobacteria,2QBUY@267890|Shewanellaceae 1236|Gammaproteobacteria G SMP-30/Gluconolaconase/LRE-like region - - 3.1.1.15 ko:K13874 ko00053,ko01100,map00053,map01100 - R02526 RC00537 ko00000,ko00001,ko01000 - - - SGL k141_33900_2 745411.B3C1_10852 1.39e-33 124.0 COG1172@1|root,COG1172@2|Bacteria,1MW9Z@1224|Proteobacteria,1RQ77@1236|Gammaproteobacteria,1J8Z2@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria U Branched-chain amino acid transport system / permease component yjfF GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - ko:K02057,ko:K10440,ko:K17209 ko02010,map02010 M00212,M00221,M00592 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.21 - iECW_1372.ECW_m4592,iEKO11_1354.EKO11_4080,iWFL_1372.ECW_m4592 BPD_transp_2 k141_735_1 1453501.JELR01000002_gene689 1.94e-70 221.0 COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,1RN2A@1236|Gammaproteobacteria,464MN@72275|Alteromonadaceae 1236|Gammaproteobacteria E The glycine cleavage system catalyzes the degradation of glycine gcvT GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.1.2.10 ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 M00532 R01221,R02300,R04125 RC00022,RC00069,RC00183,RC02834 ko00000,ko00001,ko00002,ko01000 - - iSFV_1184.SFV_2953 GCV_T,GCV_T_C k141_735_2 1453501.JELR01000002_gene688 3.16e-81 241.0 COG0509@1|root,COG0509@2|Bacteria,1RGV7@1224|Proteobacteria,1S656@1236|Gammaproteobacteria,46758@72275|Alteromonadaceae 1236|Gammaproteobacteria E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein gcvH GO:0001505,GO:0003674,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008289,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0017144,GO:0019464,GO:0019752,GO:0031405,GO:0031406,GO:0033293,GO:0036094,GO:0042133,GO:0042135,GO:0042737,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0048037,GO:0050662,GO:0065007,GO:0065008,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901681 - ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 - - iE2348C_1286.E2348C_3156,iPC815.YPO0906 GCV_H k141_735_3 1453501.JELR01000002_gene687 6.67e-49 172.0 COG3605@1|root,COG3605@2|Bacteria,1QTTV@1224|Proteobacteria,1T1H2@1236|Gammaproteobacteria,464IT@72275|Alteromonadaceae 1236|Gammaproteobacteria T Belongs to the PEP-utilizing enzyme family ptsP GO:0003674,GO:0003824,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008965,GO:0009987,GO:0010033,GO:0010243,GO:0016310,GO:0016740,GO:0016772,GO:0016775,GO:0019538,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050896,GO:0071704,GO:1901564,GO:1901698 2.7.3.9 ko:K08484 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 - - - GAF,GAF_2,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C k141_21988_2 1117379.BABA_08051 9.99e-19 84.0 COG0673@1|root,COG0673@2|Bacteria,1TQ72@1239|Firmicutes,4HCS4@91061|Bacilli,1ZCPA@1386|Bacillus 91061|Bacilli S Oxidoreductase family, C-terminal alpha/beta domain - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C k141_27768_1 218284.CCDN010000002_gene2820 2.72e-103 311.0 COG0642@1|root,COG2205@2|Bacteria,1V10X@1239|Firmicutes,4HB4P@91061|Bacilli,1ZBIC@1386|Bacillus 91061|Bacilli T COG0642 Signal transduction histidine kinase hssS - - - - - - - - - - - HAMP,HATPase_c,HisKA k141_27768_2 545693.BMQ_3273 3.19e-12 64.3 COG0745@1|root,COG0745@2|Bacteria,1TSWT@1239|Firmicutes,4HBSC@91061|Bacilli,1ZCSV@1386|Bacillus 91061|Bacilli T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - - - - - - - - - - Response_reg,Trans_reg_C k141_19659_1 1453501.JELR01000005_gene1791 8.31e-282 801.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,464CD@72275|Alteromonadaceae 1236|Gammaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family mtrD_1 - - ko:K18138,ko:K18307 ko01501,ko01503,ko02024,map01501,map01503,map02024 M00644,M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2,2.A.6.2.20,2.A.6.2.32 - - ACR_tran k141_27927_3 1444310.JANV01000162_gene1192 1.89e-22 92.0 COG1694@1|root,COG1694@2|Bacteria,1VIQA@1239|Firmicutes,4HSHR@91061|Bacilli,1ZNVF@1386|Bacillus 91061|Bacilli S MazG nucleotide pyrophosphohydrolase domain - - - - - - - - - - - - MazG k141_27927_4 1234664.AMRO01000024_gene1796 4.69e-28 106.0 2DM82@1|root,324KK@2|Bacteria,1V9IJ@1239|Firmicutes,4HJEV@91061|Bacilli,1WGSK@129337|Geobacillus 91061|Bacilli - - - - 3.1.22.4 ko:K01159 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - - k141_7911_1 218284.CCDN010000003_gene2984 8.03e-286 784.0 COG1207@1|root,COG1207@2|Bacteria,1TP88@1239|Firmicutes,4H9V5@91061|Bacilli,1ZAVH@1386|Bacillus 91061|Bacilli M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain glmU GO:0000270,GO:0000271,GO:0003674,GO:0003824,GO:0003977,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006629,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0030203,GO:0033692,GO:0034637,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509 2.3.1.157,2.7.7.23 ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00362 R00416,R05332 RC00002,RC00004,RC00166 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transf_3,NTP_transferase k141_7911_2 218284.CCDN010000003_gene2985 4.09e-221 610.0 COG0462@1|root,COG0462@2|Bacteria,1TQ6Q@1239|Firmicutes,4HB61@91061|Bacilli,1ZD4C@1386|Bacillus 91061|Bacilli F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) prs GO:0003674,GO:0003824,GO:0004749,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - Pribosyl_synth,Pribosyltran_N k141_9272_1 218284.CCDN010000007_gene4011 3.61e-195 548.0 COG0766@1|root,COG0766@2|Bacteria,1TPAU@1239|Firmicutes,4H9KI@91061|Bacilli,1ZB89@1386|Bacillus 91061|Bacilli M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine murA - 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R00660 RC00350 ko00000,ko00001,ko01000,ko01011 - - - EPSP_synthase k141_25918_1 1535422.ND16A_1731 0.0 992.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_25918_2 1279017.AQYJ01000022_gene2711 4.73e-32 113.0 COG2040@1|root,COG2040@2|Bacteria,1N7A3@1224|Proteobacteria,1SCA1@1236|Gammaproteobacteria,468HX@72275|Alteromonadaceae 1236|Gammaproteobacteria E Protein of unknown function (DUF2789) XAC1354 - - - - - - - - - - - DUF2789 k141_35377_1 218284.CCDN010000005_gene3248 1.11e-165 471.0 COG2182@1|root,COG2182@2|Bacteria,1TPU9@1239|Firmicutes,4HBHE@91061|Bacilli,1ZBWG@1386|Bacillus 91061|Bacilli G COG2182 Maltose-binding periplasmic proteins domains cycB - - ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 M00207,M00491,M00599 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.16,3.A.1.1.2,3.A.1.1.38 - - SBP_bac_8 k141_36303_1 218284.CCDN010000007_gene3904 3.39e-170 481.0 COG1168@1|root,COG1168@2|Bacteria,1TP5G@1239|Firmicutes,4H9PE@91061|Bacilli,1ZCQC@1386|Bacillus 91061|Bacilli E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities patB - 4.4.1.8 ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 - R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 k141_4334_1 218284.CCDN010000001_gene1667 7.66e-83 250.0 COG0572@1|root,COG0572@2|Bacteria,1V4T0@1239|Firmicutes,4HHU2@91061|Bacilli,1ZGDF@1386|Bacillus 91061|Bacilli F Phosphoribulokinase / Uridine kinase family - - 2.7.1.48 ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PRK k141_914_1 1116375.VEJY3_16931 4.39e-33 121.0 COG2197@1|root,COG2197@2|Bacteria,1RDI0@1224|Proteobacteria,1RS5N@1236|Gammaproteobacteria,1XU91@135623|Vibrionales 135623|Vibrionales K helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE k141_914_2 223926.28808534 3.39e-263 725.0 COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,1RPKC@1236|Gammaproteobacteria,1XVI5@135623|Vibrionales 135623|Vibrionales J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) tyrS1 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006437,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - S4,tRNA-synt_1b k141_18859_1 1116375.VEJY3_00800 1.8e-79 252.0 COG4166@1|root,COG4166@2|Bacteria,1MUVU@1224|Proteobacteria,1RMA1@1236|Gammaproteobacteria,1XUMM@135623|Vibrionales 135623|Vibrionales E ABC-type oligopeptide transport system, periplasmic component - - - ko:K13893 ko02010,map02010 M00349 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.21,3.A.1.5.24 - - SBP_bac_5 k141_18859_2 1116375.VEJY3_00805 1.09e-149 424.0 COG0444@1|root,COG0444@2|Bacteria,1R4KB@1224|Proteobacteria,1SMBI@1236|Gammaproteobacteria,1XTVM@135623|Vibrionales 135623|Vibrionales P Belongs to the ABC transporter superfamily dppD - - ko:K02031 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - ABC_tran,oligo_HPY k141_25919_1 42565.FP66_12570 4.69e-119 356.0 COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,1XIJT@135619|Oceanospirillales 135619|Oceanospirillales M gamma-glutamyltransferase ggt - 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept k141_6841_1 218284.CCDN010000001_gene537 1.54e-174 491.0 COG1484@1|root,COG1484@2|Bacteria,1TPZX@1239|Firmicutes,4HABS@91061|Bacilli,1ZB6G@1386|Bacillus 91061|Bacilli L Primosomal protein DnaI dnaI GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - ko:K11144 - - - - ko00000,ko03032 - - - DnaI_N,IstB_IS21 k141_24630_1 218284.CCDN010000002_gene2179 5.27e-98 291.0 COG1300@1|root,COG1300@2|Bacteria,1U15U@1239|Firmicutes,4HEDT@91061|Bacilli,1ZDAQ@1386|Bacillus 91061|Bacilli S Stage II sporulation protein M - - - - - - - - - - - - SpoIIM k141_24630_2 218284.CCDN010000002_gene2178 3.64e-26 105.0 COG1721@1|root,COG1721@2|Bacteria,1UYJ3@1239|Firmicutes,4HBP9@91061|Bacilli,1ZEFE@1386|Bacillus 91061|Bacilli S von Willebrand factor (vWF) type A domain - - - - - - - - - - - - DUF58 k141_9274_1 218284.CCDN010000007_gene3946 7.7e-71 232.0 COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H9SA@91061|Bacilli,1ZBUK@1386|Bacillus 91061|Bacilli M penicillin-binding protein pbpG GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.4.1.129,3.4.16.4 ko:K21464 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase k141_35378_2 218284.CCDN010000001_gene1732 4.93e-108 318.0 COG1284@1|root,COG1284@2|Bacteria,1TQTP@1239|Firmicutes,4HBV2@91061|Bacilli,1ZCF3@1386|Bacillus 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2179) - - - - - - - - - - - - DUF2179,YitT_membrane k141_7912_1 1169144.KB910955_gene237 1.31e-104 316.0 COG0438@1|root,COG0438@2|Bacteria,1UZ16@1239|Firmicutes,4HEY1@91061|Bacilli,1ZFB2@1386|Bacillus 91061|Bacilli M Glycosyltransferase Family 4 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 k141_16247_1 1274374.CBLK010000088_gene4718 1.05e-15 78.6 COG0791@1|root,COG0791@2|Bacteria,1V9ZW@1239|Firmicutes,4HH84@91061|Bacilli,26SGY@186822|Paenibacillaceae 91061|Bacilli M Hydrolase - - - ko:K21471 - - - - ko00000,ko01000,ko01002,ko01011 - - - NLPC_P60,SH3_3 k141_32808_1 266117.Rxyl_0755 8.67e-29 111.0 COG0842@1|root,COG0842@2|Bacteria,2ICWC@201174|Actinobacteria,4CQA1@84995|Rubrobacteria 84995|Rubrobacteria V ABC-2 type transporter - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane k141_15016_1 1140001.I571_01118 8.26e-100 298.0 COG0561@1|root,COG0561@2|Bacteria,1V2N1@1239|Firmicutes,4HAFS@91061|Bacilli,4AZ9J@81852|Enterococcaceae 91061|Bacilli S Sucrose-6F-phosphate phosphohydrolase supH - - - - - - - - - - - Hydrolase_3 k141_15016_2 702450.CUW_1008 1.74e-33 120.0 COG0110@1|root,COG0110@2|Bacteria,1V2KW@1239|Firmicutes 1239|Firmicutes S Transfers acetyl group from acetyl-CoA to the 6-hydroxyl of galactopyranosides lacA - - - - - - - - - - - Hexapep,Mac k141_30321_1 1136138.JH604622_gene2050 1.29e-57 190.0 COG1902@1|root,COG1902@2|Bacteria,1MVIX@1224|Proteobacteria,1RMFI@1236|Gammaproteobacteria 1236|Gammaproteobacteria C nadh flavin - - - ko:K10680 ko00633,ko01120,map00633,map01120 - R08014,R08017,R08042 RC00250 ko00000,ko00001,ko01000 - - - Oxidored_FMN k141_3120_1 1336233.JAEH01000016_gene3050 2.53e-39 144.0 COG0673@1|root,COG0673@2|Bacteria,1PE56@1224|Proteobacteria,1RWPI@1236|Gammaproteobacteria,2QBFA@267890|Shewanellaceae 1236|Gammaproteobacteria S Glycosyl hydrolase family 109 protein - - - - - - - - - - - - GFO_IDH_MocA,TAT_signal k141_11670_2 1273538.G159_19020 1e-44 154.0 COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4HBB9@91061|Bacilli,26CUU@186818|Planococcaceae 91061|Bacilli EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components - - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1,OppC_N k141_18893_1 1453501.JELR01000002_gene99 9.32e-60 188.0 2BGQ8@1|root,32AP7@2|Bacteria,1RHYY@1224|Proteobacteria,1S82X@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Hemerythrin HHE cation binding domain - - - - - - - - - - - - Hemerythrin k141_25941_1 1131730.BAVI_17637 3.88e-68 215.0 COG0454@1|root,COG0456@2|Bacteria,1V2SN@1239|Firmicutes,4HGC0@91061|Bacilli,1ZD79@1386|Bacillus 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10,Acetyltransf_7 k141_1883_2 1415778.JQMM01000001_gene1151 4.34e-100 303.0 COG0462@1|root,COG0462@2|Bacteria,1MUV7@1224|Proteobacteria,1RY55@1236|Gammaproteobacteria,1JACS@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria F Belongs to the ribose-phosphate pyrophosphokinase family - - 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - Pribosyltran,Pribosyltran_N k141_1883_3 1122194.AUHU01000004_gene1444 1.14e-220 625.0 COG0213@1|root,COG0213@2|Bacteria,1MV3H@1224|Proteobacteria,1RPTG@1236|Gammaproteobacteria,4661E@72275|Alteromonadaceae 1236|Gammaproteobacteria F The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis - - 2.4.2.4 ko:K00758 ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219 - R01570,R02484,R08222,R08230 RC00063 ko00000,ko00001,ko01000 - - - Glycos_trans_3N,Glycos_transf_3,PYNP_C k141_1883_4 1279017.AQYJ01000021_gene2803 3.78e-132 384.0 COG0589@1|root,COG0589@2|Bacteria,1MVZS@1224|Proteobacteria,1SZCP@1236|Gammaproteobacteria,46CY1@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - - - - - - - - - - Usp k141_1883_5 1042377.AFPJ01000020_gene2090 0.0 945.0 COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,1RMT7@1236|Gammaproteobacteria,466AZ@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - DUF885 k141_1883_6 1042377.AFPJ01000020_gene2089 5.77e-131 372.0 COG0605@1|root,COG0605@2|Bacteria,1MVW2@1224|Proteobacteria,1RP7X@1236|Gammaproteobacteria,4648W@72275|Alteromonadaceae 1236|Gammaproteobacteria P Destroys radicals which are normally produced within the cells and which are toxic to biological systems sodB GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1 ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 - - - ko00000,ko00001,ko01000 - - iAF1260.b1656,iAPECO1_1312.APECO1_736,iB21_1397.B21_01616,iBWG_1329.BWG_1471,iE2348C_1286.E2348C_1742,iEC042_1314.EC042_1825,iEC55989_1330.EC55989_1824,iECABU_c1320.ECABU_c19090,iECBD_1354.ECBD_1987,iECB_1328.ECB_01626,iECDH10B_1368.ECDH10B_1790,iECDH1ME8569_1439.ECDH1ME8569_1601,iECD_1391.ECD_01626,iECED1_1282.ECED1_1855,iECH74115_1262.ECH74115_2368,iECIAI1_1343.ECIAI1_1708,iECO103_1326.ECO103_1797,iECO111_1330.ECO111_2126,iECO26_1355.ECO26_2385,iECOK1_1307.ECOK1_1775,iECP_1309.ECP_1601,iECS88_1305.ECS88_1705,iECSE_1348.ECSE_1780,iECSP_1301.ECSP_2222,iECUMN_1333.ECUMN_1946,iECW_1372.ECW_m1823,iECs_1301.ECs2365,iEKO11_1354.EKO11_2118,iETEC_1333.ETEC_1691,iEcDH1_1363.EcDH1_1984,iEcE24377_1341.EcE24377A_1869,iEcHS_1320.EcHS_A1735,iEcSMS35_1347.EcSMS35_1542,iEcolC_1368.EcolC_1973,iG2583_1286.G2583_2051,iJO1366.b1656,iJR904.b1656,iLF82_1304.LF82_2148,iNRG857_1313.NRG857_08300,iSBO_1134.SBO_1475,iSDY_1059.SDY_1882,iSFV_1184.SFV_1678,iSF_1195.SF1684,iSFxv_1172.SFxv_1892,iSSON_1240.SSON_1500,iS_1188.S1816,iSbBS512_1146.SbBS512_E1853,iUMN146_1321.UM146_08870,iUMNK88_1353.UMNK88_2117,iUTI89_1310.UTI89_C1847,iWFL_1372.ECW_m1823,iY75_1357.Y75_RS08680,iZ_1308.Z2678,ic_1306.c2050 Sod_Fe_C,Sod_Fe_N k141_1883_7 1279017.AQYJ01000021_gene2808 2.84e-74 233.0 COG2959@1|root,COG2959@2|Bacteria,1N3SM@1224|Proteobacteria,1S9N7@1236|Gammaproteobacteria,46870@72275|Alteromonadaceae 1236|Gammaproteobacteria H enzyme of heme biosynthesis - - - - - - - - - - - - - k141_35393_2 1279019.ARQK01000057_gene851 3.87e-20 87.4 COG1335@1|root,COG1335@2|Bacteria,1MV0W@1224|Proteobacteria,1RQJ7@1236|Gammaproteobacteria,1WXHF@135613|Chromatiales 135613|Chromatiales Q PFAM isochorismatase hydrolase - - - - - - - - - - - - Isochorismatase k141_27311_1 1122194.AUHU01000003_gene2124 1.09e-29 110.0 COG3682@1|root,COG3682@2|Bacteria,1N03Y@1224|Proteobacteria,1SBVR@1236|Gammaproteobacteria,467YD@72275|Alteromonadaceae 1236|Gammaproteobacteria K Penicillinase repressor - - - - - - - - - - - - Penicillinase_R k141_18894_1 1294265.JCM21738_2715 8.05e-88 263.0 COG0483@1|root,COG0483@2|Bacteria,1TR4E@1239|Firmicutes,4HB92@91061|Bacilli,1ZAS1@1386|Bacillus 91061|Bacilli G Inositol monophosphatase suhB GO:0003674,GO:0003824,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 - - - Inositol_P k141_11671_2 698769.JFBD01000002_gene2763 3.57e-06 48.1 2DK96@1|root,308WX@2|Bacteria,1U439@1239|Firmicutes,4IDVA@91061|Bacilli,4C718@84406|Virgibacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_12881_1 290317.Cpha266_1676 3.4e-37 137.0 COG1173@1|root,COG1173@2|Bacteria,1FD9T@1090|Chlorobi 1090|Chlorobi EP PFAM binding-protein-dependent transport systems inner membrane component - - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1,OppC_N k141_9310_1 1453501.JELR01000002_gene951 2.54e-73 224.0 COG0835@1|root,COG0835@2|Bacteria,1NA8G@1224|Proteobacteria,1S8Q6@1236|Gammaproteobacteria,46CTM@72275|Alteromonadaceae 1236|Gammaproteobacteria NT CheW-like domain - - - ko:K06598 ko02020,ko02025,map02020,map02025 - - - ko00000,ko00001,ko02035 - - - CheW k141_16262_1 218284.CCDN010000001_gene1007 2e-178 506.0 COG0364@1|root,COG0364@2|Bacteria,1TPYF@1239|Firmicutes,4HA73@91061|Bacilli,1ZCZ3@1386|Bacillus 91061|Bacilli G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone zwf - 1.1.1.363,1.1.1.49 ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 M00004,M00006,M00008 R00835,R02736,R10907 RC00001,RC00066 ko00000,ko00001,ko00002,ko01000,ko04147 - - - G6PD_C,G6PD_N k141_36325_1 1484479.DI14_14525 6.92e-50 176.0 COG0446@1|root,COG0607@1|root,COG2210@1|root,COG0446@2|Bacteria,COG0607@2|Bacteria,COG2210@2|Bacteria,1TPWW@1239|Firmicutes,4HA11@91061|Bacilli,3WENZ@539002|Bacillales incertae sedis 91061|Bacilli P Belongs to the sulfur carrier protein TusA family cdr - - - - - - - - - - - DrsE_2,Pyr_redox_2,Pyr_redox_dim,Rhodanese,TusA k141_34138_1 1196031.ALEG01000028_gene4107 2.43e-32 121.0 COG0476@1|root,COG0476@2|Bacteria,1TQ3U@1239|Firmicutes,4HBGP@91061|Bacilli,1ZBR4@1386|Bacillus 91061|Bacilli H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 moeB GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779 2.7.7.73,2.7.7.80 ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07459 RC00043 ko00000,ko00001,ko01000 - - - ThiF k141_34138_2 935836.JAEL01000017_gene829 1.74e-41 139.0 2DQIA@1|root,3371K@2|Bacteria,1VHCJ@1239|Firmicutes,4HMJ4@91061|Bacilli,1ZR81@1386|Bacillus 91061|Bacilli S Heat induced stress protein YflT - - - - - - - - - - - - YflT k141_35394_1 1268072.PSAB_04085 1.35e-30 110.0 COG3708@1|root,COG3708@2|Bacteria,1VJT1@1239|Firmicutes,4HREN@91061|Bacilli,26Z6R@186822|Paenibacillaceae 91061|Bacilli K Putative zinc ribbon domain - - - - - - - - - - - - Zn_ribbon_2 k141_35394_2 406124.ACPC01000046_gene2352 2.61e-14 72.8 COG3119@1|root,COG3119@2|Bacteria,1UDRD@1239|Firmicutes,4HD9J@91061|Bacilli,1ZCSX@1386|Bacillus 91061|Bacilli P Protein of unknown function (DUF229) - - - - - - - - - - - - DUF4976,Sulfatase k141_29310_1 1166948.JPZL01000001_gene2190 6.77e-69 222.0 COG2252@1|root,COG2252@2|Bacteria,1MUV0@1224|Proteobacteria,1RMBE@1236|Gammaproteobacteria,1XI24@135619|Oceanospirillales 135619|Oceanospirillales S Permease - - - ko:K06901 - - - - ko00000,ko02000 2.A.1.40 - - Xan_ur_permease k141_32823_1 1453501.JELR01000002_gene46 1.6e-24 96.7 COG2137@1|root,COG2137@2|Bacteria,1N6P6@1224|Proteobacteria,1SCMF@1236|Gammaproteobacteria,468BK@72275|Alteromonadaceae 1236|Gammaproteobacteria S Modulates RecA activity recX GO:0003674,GO:0005488,GO:0005515,GO:0006282,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0019219,GO:0019222,GO:0019899,GO:0030234,GO:0031323,GO:0031668,GO:0033554,GO:0043086,GO:0044092,GO:0048583,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0071496,GO:0080090,GO:0080134,GO:0080135,GO:0098772,GO:2001020 - ko:K03565 - - - - ko00000,ko03400 - - - RecX k141_32823_2 1279017.AQYJ01000018_gene777 6.72e-235 656.0 COG0554@1|root,COG0554@2|Bacteria,1MUP7@1224|Proteobacteria,1RMAF@1236|Gammaproteobacteria,464DH@72275|Alteromonadaceae 1236|Gammaproteobacteria C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate glpK GO:0003674,GO:0003824,GO:0004370,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019405,GO:0019563,GO:0019751,GO:0033554,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046164,GO:0046174,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:1901575,GO:1901615,GO:1901616 2.7.1.30 ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 - R00847 RC00002,RC00017 ko00000,ko00001,ko01000,ko04147 - - iE2348C_1286.E2348C_4230,iECNA114_1301.ECNA114_4065,iECSF_1327.ECSF_3786 FGGY_C,FGGY_N k141_6870_1 935836.JAEL01000003_gene396 1.86e-42 149.0 COG0614@1|root,COG0614@2|Bacteria,1UNE3@1239|Firmicutes,4H9ZX@91061|Bacilli,1ZBS8@1386|Bacillus 91061|Bacilli P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component yvrC - - ko:K02016 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - Peripla_BP_2 k141_16263_1 218284.CCDN010000006_gene3586 2.04e-97 296.0 COG4325@1|root,COG4325@2|Bacteria,1TSK8@1239|Firmicutes,4HCYY@91061|Bacilli,1ZR6S@1386|Bacillus 91061|Bacilli S Predicted membrane protein (DUF2254) - - - - - - - - - - - - DUF2254 k141_11672_1 1196031.ALEG01000061_gene2114 1.24e-224 625.0 COG0621@1|root,COG0621@2|Bacteria,1TPBR@1239|Firmicutes,4HBYZ@91061|Bacilli,1ZB8Q@1386|Bacillus 91061|Bacilli J ribosomal protein S12 methylthiotransferase yqeV GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035598,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360 2.8.4.5 ko:K18707 - - R10649 RC00003,RC03221 ko00000,ko01000,ko03016 - - - Radical_SAM,TRAM,UPF0004 k141_18896_2 420662.Mpe_A0747 9.94e-05 49.7 COG3837@1|root,COG3837@2|Bacteria,1PR0G@1224|Proteobacteria,2WBKD@28216|Betaproteobacteria,1KP4X@119065|unclassified Burkholderiales 28216|Betaproteobacteria S Cupin domain - - - - - - - - - - - - Cupin_2 k141_29311_1 42565.FP66_15300 2.83e-117 346.0 COG1249@1|root,COG1249@2|Bacteria,1MU2Z@1224|Proteobacteria,1RMC0@1236|Gammaproteobacteria,1XI13@135619|Oceanospirillales 135619|Oceanospirillales C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family gor - 1.8.1.7 ko:K00383 ko00480,ko04918,map00480,map04918 - R00094,R00115 RC00011 ko00000,ko00001,ko01000 - - - Pyr_redox_2,Pyr_redox_dim k141_14209_1 218284.CCDN010000006_gene3680 1.48e-98 293.0 COG2177@1|root,COG2177@2|Bacteria,1TPND@1239|Firmicutes,4HA5A@91061|Bacilli,1ZC4Q@1386|Bacillus 91061|Bacilli D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation ftsX GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0007154,GO:0007165,GO:0007166,GO:0008150,GO:0008356,GO:0009966,GO:0009987,GO:0010033,GO:0010646,GO:0016020,GO:0016043,GO:0019221,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0023052,GO:0032506,GO:0034097,GO:0042173,GO:0042221,GO:0043937,GO:0043938,GO:0044085,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051301,GO:0051716,GO:0065007,GO:0070098,GO:0070297,GO:0070887,GO:0071310,GO:0071345,GO:0071840,GO:0071944,GO:0090529,GO:1902531 - ko:K09811 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - FtsX k141_943_1 1300005.R9RFE7_9CAUD 1.71e-11 67.4 4QFX3@10239|Viruses,4QZCU@35237|dsDNA viruses no RNA stage,4QQCQ@28883|Caudovirales,4QNCR@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k141_943_2 1453501.JELR01000002_gene76 1.75e-60 195.0 COG0037@1|root,COG0037@2|Bacteria,1MW5Q@1224|Proteobacteria,1RN2H@1236|Gammaproteobacteria,464FD@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system ttcA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0016783,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360 - ko:K14058 - - - - ko00000,ko03016 - - - ATP_bind_3 k141_9311_1 218284.CCDN010000001_gene228 1.21e-161 461.0 COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,4HA7K@91061|Bacilli,1ZDDX@1386|Bacillus 91061|Bacilli F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction ackA - 2.7.2.1 ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00315,R01353 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - Acetate_kinase k141_1885_1 218284.CCDN010000001_gene1013 1.34e-84 258.0 COG0345@1|root,COG0345@2|Bacteria,1TP1E@1239|Firmicutes,4H9RV@91061|Bacilli,1ZCWZ@1386|Bacillus 91061|Bacilli E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline proC - 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 - - - F420_oxidored,P5CR_dimer k141_19909_2 42565.FP66_06455 6.05e-21 85.1 COG0222@1|root,COG0222@2|Bacteria,1RGU4@1224|Proteobacteria,1S5V7@1236|Gammaproteobacteria,1XJXD@135619|Oceanospirillales 135619|Oceanospirillales J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation rplL - - ko:K02935 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L12,Ribosomal_L12_N k141_34139_1 1453501.JELR01000001_gene3031 1.45e-110 338.0 COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,465W3@72275|Alteromonadaceae 1236|Gammaproteobacteria T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - GAF_2,HAMP,HATPase_c,HisKA,Hpt,NMT1,PAS,PAS_3,PAS_4,PAS_9,Response_reg k141_36327_1 1179773.BN6_39190 0.000204 47.0 COG4319@1|root,COG4319@2|Bacteria,2IMHY@201174|Actinobacteria,4EBHJ@85010|Pseudonocardiales 201174|Actinobacteria S SnoaL-like domain - - - - - - - - - - - - DUF4440,SnoaL_2,SnoaL_3 k141_25942_1 218284.CCDN010000001_gene665 7.7e-129 389.0 COG0608@1|root,COG0608@2|Bacteria,1TPXE@1239|Firmicutes,4H9UP@91061|Bacilli,1ZBAT@1386|Bacillus 91061|Bacilli L Single-stranded-DNA-specific exonuclease RecJ recJ - - ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1,ssDNA-exonuc_C k141_11674_1 935836.JAEL01000024_gene2432 1.93e-94 287.0 COG4303@1|root,COG4303@2|Bacteria,1TP15@1239|Firmicutes,4HBSM@91061|Bacilli,1ZD42@1386|Bacillus 91061|Bacilli E Ethanolamine ammonia lyase large subunit (EutB) eutB - 4.3.1.7 ko:K03735,ko:K16785 ko00564,ko01100,ko02010,map00564,map01100,map02010 M00582 R00749 RC00370 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - EutB k141_32824_1 1002809.SSIL_2406 4.85e-98 295.0 COG0451@1|root,COG0451@2|Bacteria 2|Bacteria GM ADP-glyceromanno-heptose 6-epimerase activity - - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase k141_20928_1 218284.CCDN010000001_gene1893 0.0 1012.0 COG2176@1|root,COG2176@2|Bacteria,1TPAG@1239|Firmicutes,4H9RF@91061|Bacilli,1ZCIB@1386|Bacillus 91061|Bacilli L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity polC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.7.7 ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_a_NI,DNA_pol3_a_NII,DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon k141_37534_2 218284.CCDN010000007_gene3801 2.18e-75 232.0 COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,4H9TB@91061|Bacilli,1ZBDT@1386|Bacillus 91061|Bacilli K Belongs to the ParB family spo0J GO:0005575,GO:0005622,GO:0005623,GO:0007059,GO:0008150,GO:0009295,GO:0009987,GO:0022603,GO:0042173,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0043937,GO:0043938,GO:0044424,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0065007 - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - HTH_3,KorB,ParBc k141_10421_1 983545.Glaag_2490 3.48e-64 208.0 COG2819@1|root,COG2819@2|Bacteria,1RAB4@1224|Proteobacteria,1S2JK@1236|Gammaproteobacteria,466QX@72275|Alteromonadaceae 1236|Gammaproteobacteria S Putative esterase Z012_06880 - - - - - - - - - - - Esterase k141_6873_1 218284.CCDN010000001_gene1531 8.43e-189 536.0 COG0578@1|root,COG0578@2|Bacteria,1TQJN@1239|Firmicutes,4HAG8@91061|Bacilli,1ZCGN@1386|Bacillus 91061|Bacilli C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family glpD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.1.3.21,1.1.5.3 ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 - R00846,R00848 RC00029 ko00000,ko00001,ko01000 - - - DAO,DAO_C k141_27314_2 1196031.ALEG01000033_gene3011 7.72e-241 669.0 COG3876@1|root,COG3876@2|Bacteria,1VRMG@1239|Firmicutes,4HA8F@91061|Bacilli,1ZBF3@1386|Bacillus 91061|Bacilli S protein conserved in bacteria ybbC - - - - - - - - - - - DUF1343 k141_945_2 1120950.KB892739_gene4001 1.45e-12 69.3 COG1022@1|root,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria,4DNTY@85009|Propionibacteriales 201174|Actinobacteria I AMP-binding enzyme fadD11_1 - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding k141_22293_2 406124.ACPC01000018_gene2533 4.55e-105 312.0 COG0604@1|root,COG0604@2|Bacteria,1V55H@1239|Firmicutes,4HD0S@91061|Bacilli,1ZPZT@1386|Bacillus 91061|Bacilli C Zinc-binding dehydrogenase - - - - - - - - - - - - ADH_N,ADH_zinc_N,ADH_zinc_N_2 k141_11675_1 1444310.JANV01000205_gene623 8.91e-68 211.0 COG1875@1|root,COG1875@2|Bacteria,1V4CX@1239|Firmicutes 1239|Firmicutes T PhoH-like protein - - - ko:K07175 - - - - ko00000 - - - PhoH k141_11675_2 1423321.AS29_00445 3.66e-28 113.0 COG0209@1|root,COG0209@2|Bacteria,1TPFH@1239|Firmicutes,4HA07@91061|Bacilli,1ZCST@1386|Bacillus 91061|Bacilli F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen nrdA - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_lgC,Ribonuc_red_lgN k141_17659_1 293826.Amet_1426 4.53e-43 149.0 COG2720@1|root,COG2720@2|Bacteria,1TQM8@1239|Firmicutes,24AE8@186801|Clostridia,36HTW@31979|Clostridiaceae 186801|Clostridia V VanW like protein - - - ko:K18346 ko01502,ko02020,map01502,map02020 M00651 - - ko00000,ko00001,ko00002,ko01504 - - - VanW k141_30506_1 1089439.KB902262_gene168 2.25e-21 95.1 COG0500@1|root,COG2226@2|Bacteria,1R179@1224|Proteobacteria 1224|Proteobacteria Q Mycolic acid cyclopropane synthetase - - - - - - - - - - - - Methyltransf_11 k141_36481_1 1042377.AFPJ01000007_gene1879 1.17e-115 354.0 COG0417@1|root,COG0417@2|Bacteria,1MVY9@1224|Proteobacteria,1RMQ1@1236|Gammaproteobacteria,4640I@72275|Alteromonadaceae 1236|Gammaproteobacteria L DNA polymerase polB GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0018130,GO:0019438,GO:0031668,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0045004,GO:0045005,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02336 - - - - ko00000,ko01000,ko03400 - - - DNA_pol_B,DNA_pol_B_exo1 k141_28214_2 1279017.AQYJ01000028_gene2120 2.24e-138 400.0 COG2819@1|root,COG2819@2|Bacteria,1PTJI@1224|Proteobacteria,1T1D3@1236|Gammaproteobacteria,464H2@72275|Alteromonadaceae 1236|Gammaproteobacteria S Putative esterase - - - - - - - - - - - - Esterase k141_10591_1 333138.LQ50_07825 1.96e-56 183.0 2BZV8@1|root,30HHG@2|Bacteria,1V68P@1239|Firmicutes,4HHRU@91061|Bacilli,1ZIAG@1386|Bacillus 91061|Bacilli S Replication-relaxation - - - - - - - - - - - - Replic_Relax k141_34357_1 218284.CCDN010000001_gene1864 7.4e-103 309.0 COG0612@1|root,COG0612@2|Bacteria,1TPN6@1239|Firmicutes,4H9P5@91061|Bacilli,1ZCAJ@1386|Bacillus 91061|Bacilli S Peptidase M16 albE - - - - - - - - - - - Peptidase_M16_C k141_17660_1 666686.B1NLA3E_20405 1.09e-57 193.0 COG4191@1|root,COG4191@2|Bacteria,1UHS4@1239|Firmicutes,4HCZT@91061|Bacilli,1ZD9G@1386|Bacillus 91061|Bacilli T Histidine kinase glnJ - 2.7.13.3 ko:K07717 ko02020,map02020 M00518 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c k141_3379_1 283699.D172_1029 0.000162 50.1 COG2931@1|root,COG3227@1|root,COG3266@1|root,COG4932@1|root,COG2931@2|Bacteria,COG3227@2|Bacteria,COG3266@2|Bacteria,COG4932@2|Bacteria,1P416@1224|Proteobacteria,1RR7I@1236|Gammaproteobacteria,2Q38W@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria EMQ Thermolysin metallopeptidase, catalytic domain proA GO:0005575,GO:0005576 3.4.24.25,3.4.24.26 ko:K01399,ko:K08604 ko01503,ko02024,ko05110,ko05111,map01503,map02024,map05110,map05111 - - - ko00000,ko00001,ko01000,ko01002 - - - FTP,PepSY,Peptidase_M4,Peptidase_M4_C k141_36482_1 1078085.HMPREF1210_01891 7.65e-11 61.6 COG1960@1|root,COG1960@2|Bacteria,1TSN3@1239|Firmicutes,4HB0T@91061|Bacilli,26DGU@186818|Planococcaceae 91061|Bacilli I Acyl-CoA dehydrogenase, middle domain - - 1.3.8.7 ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_37788_1 218284.CCDN010000004_gene3057 2.67e-131 376.0 COG1489@1|root,COG1489@2|Bacteria,1V1GZ@1239|Firmicutes,4HCPN@91061|Bacilli,1ZGDB@1386|Bacillus 91061|Bacilli S Sugar fermentation stimulation protein sfsA - - ko:K06206 - - - - ko00000 - - - SfsA k141_21169_1 1042377.AFPJ01000043_gene928 2.1e-88 272.0 COG0477@1|root,COG2814@2|Bacteria,1MW59@1224|Proteobacteria,1RNUU@1236|Gammaproteobacteria,465JY@72275|Alteromonadaceae 1236|Gammaproteobacteria EGP COG0477 Permeases of the major facilitator superfamily - - - - - - - - - - - - MFS_1 k141_2149_1 1116375.VEJY3_02970 3.52e-43 142.0 COG2914@1|root,COG2914@2|Bacteria,1MZCH@1224|Proteobacteria,1SCHG@1236|Gammaproteobacteria,1XXAY@135623|Vibrionales 135623|Vibrionales S Belongs to the UPF0125 (RnfH) family yfjF - - ko:K09801 - - - - ko00000 - - - Ub-RnfH k141_2149_2 1116375.VEJY3_02965 1.48e-97 284.0 COG2867@1|root,COG2867@2|Bacteria,1RGUH@1224|Proteobacteria,1S61C@1236|Gammaproteobacteria,1XWWV@135623|Vibrionales 135623|Vibrionales I oligoketide cyclase lipid transport protein ratA GO:0003674,GO:0005488,GO:0006417,GO:0006446,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044877,GO:0045947,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:2000112,GO:2000113 - - - - - - - - - - Polyketide_cyc k141_2149_3 223926.28805630 2.47e-105 305.0 COG0691@1|root,COG0691@2|Bacteria,1RDFP@1224|Proteobacteria,1S3PT@1236|Gammaproteobacteria,1XTV7@135623|Vibrionales 135623|Vibrionales J Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene smpB - - ko:K03664 - - - - ko00000 - - - SmpB k141_31642_1 218284.CCDN010000012_gene4445 5.74e-96 295.0 COG2812@1|root,COG2812@2|Bacteria,1TPS9@1239|Firmicutes,4HAUE@91061|Bacilli,1ZB2M@1386|Bacillus 91061|Bacilli L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity dnaX GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNA_pol3_gamma3 k141_4584_1 218284.CCDN010000001_gene728 6.2e-58 192.0 COG0860@1|root,COG0860@2|Bacteria,1TSFS@1239|Firmicutes,4HACZ@91061|Bacilli,1ZAV0@1386|Bacillus 91061|Bacilli M stage II sporulation protein P spoIIP - - ko:K06385 - - - - ko00000 - - - SpoIIP k141_33101_1 218284.CCDN010000005_gene3245 1.62e-44 145.0 COG0347@1|root,COG0347@2|Bacteria,1V9Z5@1239|Firmicutes,4HJ6Z@91061|Bacilli,1ZHQA@1386|Bacillus 91061|Bacilli K Nitrogen regulatory protein P-II glnB - - ko:K04751 ko02020,map02020 - - - ko00000,ko00001 - - - P-II k141_17661_1 218284.CCDN010000001_gene700 4.55e-62 206.0 COG0768@1|root,COG0768@2|Bacteria,1TQKI@1239|Firmicutes,4HC5S@91061|Bacilli,1ZBDB@1386|Bacillus 91061|Bacilli M Penicillin-binding Protein pbpI - - ko:K21468 - - - - ko00000,ko01011 - - - PBP_dimer,Transpeptidase k141_36483_2 218284.CCDN010000001_gene1943 6.64e-112 322.0 COG1670@1|root,COG1670@2|Bacteria,1V1G0@1239|Firmicutes,4HG29@91061|Bacilli,1ZQ70@1386|Bacillus 91061|Bacilli J Acetyltransferase (GNAT) domain - - 2.3.1.82 ko:K00663 - - - - ko00000,ko01000,ko01504 - - - Acetyltransf_8 k141_34358_1 1453501.JELR01000002_gene922 2.21e-37 136.0 COG3705@1|root,COG3705@2|Bacteria,1MWIG@1224|Proteobacteria,1RPRQ@1236|Gammaproteobacteria,4649K@72275|Alteromonadaceae 1236|Gammaproteobacteria E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine hisZ - - ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002 - - - tRNA-synt_His k141_34358_2 1279017.AQYJ01000027_gene1562 1.54e-66 215.0 COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,1RNEW@1236|Gammaproteobacteria,464CH@72275|Alteromonadaceae 1236|Gammaproteobacteria F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP purA GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046033,GO:0046040,GO:0046085,GO:0046086,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 - - iECNA114_1301.ECNA114_4393,iECSF_1327.ECSF_4063,iJN746.PP_4889 Adenylsucc_synt k141_33102_1 1453501.JELR01000001_gene3270 4.13e-83 262.0 COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,1RPQD@1236|Gammaproteobacteria,469F1@72275|Alteromonadaceae 1236|Gammaproteobacteria E Creatinase/Prolidase N-terminal domain ampP - 3.4.11.9 ko:K01262 - - - - ko00000,ko01000,ko01002 - - - Creatinase_N,Creatinase_N_2,Peptidase_M24,Peptidase_M24_C k141_24957_2 458817.Shal_1983 3.27e-98 310.0 2EXJW@1|root,33QVY@2|Bacteria,1QSMJ@1224|Proteobacteria,1SK5H@1236|Gammaproteobacteria,2QA2U@267890|Shewanellaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_4585_1 1134474.O59_003774 9.67e-81 271.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MV8W@1224|Proteobacteria,1RSN6@1236|Gammaproteobacteria,1FI6I@10|Cellvibrio 1236|Gammaproteobacteria P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec k141_2150_1 1453501.JELR01000002_gene1276 6.49e-122 366.0 COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,1RMT7@1236|Gammaproteobacteria,469B8@72275|Alteromonadaceae 1236|Gammaproteobacteria S Bacterial protein of unknown function (DUF885) - - - - - - - - - - - - DUF885 k141_31644_1 1479237.JMLY01000001_gene3255 4.79e-05 47.8 COG0179@1|root,COG0179@2|Bacteria,1R4GE@1224|Proteobacteria,1S002@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q Protein of unknown function (DUF2848) - - - - - - - - - - - - DUF2848 k141_31644_2 946235.CAER01000008_gene504 0.000102 45.1 COG1802@1|root,COG1802@2|Bacteria,1TSV2@1239|Firmicutes,4HCPK@91061|Bacilli,23ITA@182709|Oceanobacillus 91061|Bacilli K FCD - - - - - - - - - - - - FCD,GntR k141_21172_1 218284.CCDN010000010_gene4330 2.95e-84 254.0 COG0860@1|root,COG0860@2|Bacteria,1TQ74@1239|Firmicutes,4HAV3@91061|Bacilli,1ZBJ8@1386|Bacillus 91061|Bacilli M n-acetylmuramoyl-L-alanine amidase cwlD GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - Amidase_3 k141_16502_1 1279017.AQYJ01000028_gene2062 1.89e-177 516.0 28IAG@1|root,2Z8D2@2|Bacteria,1P5EH@1224|Proteobacteria,1RYCA@1236|Gammaproteobacteria,4679V@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - DUF4129 k141_16502_2 83406.HDN1F_32620 7.37e-24 110.0 COG3064@1|root,COG3064@2|Bacteria,1RINZ@1224|Proteobacteria,1S7TN@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Domain of unknown function (DUF4350) - - - - - - - - - - - - DUF4350 k141_16502_3 1279017.AQYJ01000028_gene2060 1.17e-164 469.0 COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,1RN5G@1236|Gammaproteobacteria,46689@72275|Alteromonadaceae 1236|Gammaproteobacteria S ATPase family associated with various cellular activities (AAA) - - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 k141_16502_4 1279017.AQYJ01000028_gene2059 5.68e-157 457.0 COG1721@1|root,COG1721@2|Bacteria,1MXDI@1224|Proteobacteria,1RQSS@1236|Gammaproteobacteria,466PZ@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function DUF58 - - - - - - - - - - - - DUF58 k141_24958_1 218284.CCDN010000007_gene3971 4.79e-167 475.0 COG0766@1|root,COG0766@2|Bacteria,1TPAU@1239|Firmicutes,4H9KI@91061|Bacilli,1ZASB@1386|Bacillus 91061|Bacilli M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine murA GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008760,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042221,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0070589,GO:0070887,GO:0071236,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R00660 RC00350 ko00000,ko00001,ko01000,ko01011 - - iYO844.BSU37100 EPSP_synthase k141_15203_1 218284.CCDN010000008_gene4266 4.97e-180 509.0 COG0301@1|root,COG0301@2|Bacteria,1TPNW@1239|Firmicutes,4HAV9@91061|Bacilli,1ZBZY@1386|Bacillus 91061|Bacilli H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS thiI - 2.8.1.4 ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07461 - ko00000,ko00001,ko01000,ko03016 - - - THUMP,ThiI k141_15203_2 1460635.JCM19038_4187 5.12e-05 42.0 2BX75@1|root,32YCI@2|Bacteria,1VEDY@1239|Firmicutes,4HNHZ@91061|Bacilli 91061|Bacilli S spore protein - - - ko:K06418,ko:K06419 - - - - ko00000 - - - SASP k141_4587_1 218284.CCDN010000005_gene3254 1.01e-59 197.0 COG0446@1|root,COG0446@2|Bacteria,1TPWW@1239|Firmicutes,4HA11@91061|Bacilli,1ZATE@1386|Bacillus 91061|Bacilli P Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain cdr - 1.8.1.14 ko:K08255 - - - - ko00000,ko01000 - - - Pyr_redox_2,Pyr_redox_dim,Rhodanese,TusA k141_29654_1 1116375.VEJY3_13765 1.6e-127 366.0 COG0388@1|root,COG0388@2|Bacteria,1MUUB@1224|Proteobacteria,1RNVZ@1236|Gammaproteobacteria,1XSQV@135623|Vibrionales 135623|Vibrionales S Carbon-nitrogen hydrolase - - - ko:K11206 - - - - ko00000,ko01000 - - - CN_hydrolase k141_29654_2 1116375.VEJY3_13760 0.0 932.0 COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,1RMA5@1236|Gammaproteobacteria,1XTGF@135623|Vibrionales 135623|Vibrionales S Zn-dependent proteases and their inactivated homologs tldD - - ko:K03568 - - - - ko00000,ko01002 - - - PmbA_TldD k141_34389_2 1294265.JCM21738_492 3.07e-103 317.0 COG1511@1|root,COG1511@2|Bacteria,1TRMJ@1239|Firmicutes,4HB2N@91061|Bacilli,1ZBC1@1386|Bacillus 91061|Bacilli S domain protein - - - - - - - - - - - - - k141_30521_2 1211814.CAPG01000074_gene3474 1.05e-133 384.0 2EFU0@1|root,339K4@2|Bacteria,1W2KK@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - - k141_2187_2 1042377.AFPJ01000032_gene2789 3.6e-163 466.0 COG3705@1|root,COG3705@2|Bacteria,1MWIG@1224|Proteobacteria,1RPRQ@1236|Gammaproteobacteria,4649K@72275|Alteromonadaceae 1236|Gammaproteobacteria E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine hisZ - - ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002 - - - tRNA-synt_His k141_15234_1 218284.CCDN010000001_gene1970 7.16e-94 289.0 COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TYUA@1239|Firmicutes,4HDKK@91061|Bacilli,1ZPXC@1386|Bacillus 91061|Bacilli T helix_turn_helix, arabinose operon control protein ntrC - - ko:K07720 ko02020,map02020 M00519 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_18,Response_reg k141_3407_1 1279017.AQYJ01000028_gene2465 2.11e-48 162.0 COG1741@1|root,COG1741@2|Bacteria,1MVSW@1224|Proteobacteria,1RNVS@1236|Gammaproteobacteria,466FN@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the pirin family yhhW GO:0003674,GO:0003824,GO:0008127,GO:0008150,GO:0008152,GO:0016491,GO:0016701,GO:0016702,GO:0051213,GO:0055114 - ko:K06911 - - - - ko00000 - - - Pirin k141_3407_2 1453501.JELR01000002_gene1019 1.32e-68 215.0 COG0730@1|root,COG0730@2|Bacteria,1MVY3@1224|Proteobacteria,1S21M@1236|Gammaproteobacteria,467A8@72275|Alteromonadaceae 1236|Gammaproteobacteria S Sulfite exporter TauE/SafE - - - ko:K07090 - - - - ko00000 - - - TauE k141_8046_1 1453501.JELR01000001_gene2378 3.4e-43 154.0 COG3297@1|root,COG3297@2|Bacteria,1NVVW@1224|Proteobacteria,1S01F@1236|Gammaproteobacteria,4684Z@72275|Alteromonadaceae 1236|Gammaproteobacteria U GspL periplasmic domain gspL GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - ko:K02461 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - GspL_C,T2SSL k141_8046_2 1279017.AQYJ01000025_gene571 3.03e-46 153.0 COG3149@1|root,COG3149@2|Bacteria 2|Bacteria U Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins gspM - - ko:K02462 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSM k141_17704_1 1453501.JELR01000002_gene46 7.04e-72 220.0 COG2137@1|root,COG2137@2|Bacteria,1N6P6@1224|Proteobacteria,1SCMF@1236|Gammaproteobacteria,468BK@72275|Alteromonadaceae 1236|Gammaproteobacteria S Modulates RecA activity recX GO:0003674,GO:0005488,GO:0005515,GO:0006282,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0019219,GO:0019222,GO:0019899,GO:0030234,GO:0031323,GO:0031668,GO:0033554,GO:0043086,GO:0044092,GO:0048583,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0071496,GO:0080090,GO:0080134,GO:0080135,GO:0098772,GO:2001020 - ko:K03565 - - - - ko00000,ko03400 - - - RecX k141_28230_1 357804.Ping_2617 1.86e-47 164.0 COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,1RNDK@1236|Gammaproteobacteria,2QIGA@267894|Psychromonadaceae 1236|Gammaproteobacteria C Citrate synthase, C-terminal domain gltA - 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 - - - Citrate_synt k141_16541_2 1161401.ASJA01000005_gene2418 1.67e-90 293.0 COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,2TSGE@28211|Alphaproteobacteria 28211|Alphaproteobacteria U COG0457 FOG TPR repeat - - - - - - - - - - - - Sulfotransfer_3,TPR_16,TPR_19,TPR_2,TPR_8 k141_16541_3 1042377.AFPJ01000043_gene887 1.16e-86 284.0 COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,1RYP9@1236|Gammaproteobacteria,465IE@72275|Alteromonadaceae 1236|Gammaproteobacteria E ERAP1-like C-terminal domain - - 3.4.11.14 ko:K01263 - - - - ko00000,ko01000 - - - ERAP1_C,Peptidase_M1 k141_30522_1 1219072.VHA01S_024_00480 4.43e-35 131.0 COG4096@1|root,COG4096@2|Bacteria,1NUBD@1224|Proteobacteria,1SMR2@1236|Gammaproteobacteria,1XVF5@135623|Vibrionales 135623|Vibrionales V Domain of unknown function (DUF4145) - - - - - - - - - - - - DUF4145 k141_30522_2 1205908.AKXW01000068_gene2879 1.02e-23 99.0 COG2378@1|root,COG2378@2|Bacteria,1QMYB@1224|Proteobacteria,1TH80@1236|Gammaproteobacteria,1XSAV@135623|Vibrionales 135623|Vibrionales K WYL domain - - - - - - - - - - - - WYL k141_15235_1 218284.CCDN010000002_gene2629 7.02e-109 323.0 COG0477@1|root,COG2814@2|Bacteria,1UIX0@1239|Firmicutes,4ISV6@91061|Bacilli,1ZKAP@1386|Bacillus 91061|Bacilli EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 k141_29679_1 1001585.MDS_2154 8.76e-21 91.3 2C4JR@1|root,3332P@2|Bacteria,1NCYV@1224|Proteobacteria,1SEKE@1236|Gammaproteobacteria,1YGSY@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_2188_1 1274524.BSONL12_10396 1.29e-103 312.0 COG0477@1|root,COG2814@2|Bacteria,1TQHD@1239|Firmicutes,4HBCZ@91061|Bacilli,1ZDDG@1386|Bacillus 91061|Bacilli EGP COG0477 Permeases of the major facilitator superfamily - - - - - - - - - - - - MFS_1 k141_36517_1 218284.CCDN010000008_gene4188 7.97e-122 357.0 COG2081@1|root,COG2081@2|Bacteria,1TQ6E@1239|Firmicutes,4HAAT@91061|Bacilli,1ZAT3@1386|Bacillus 91061|Bacilli S HI0933-like protein ytfP - - ko:K07007 - - - - ko00000 - - - HI0933_like k141_17707_1 926569.ANT_03290 2.17e-79 252.0 COG0119@1|root,COG0119@2|Bacteria,2G5V9@200795|Chloroflexi 200795|Chloroflexi H Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) leuA - 2.3.3.13 ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 M00432 R01213 RC00004,RC00470,RC02754 br01601,ko00000,ko00001,ko00002,ko01000 - - - HMGL-like,LeuA_dimer k141_30523_1 218284.CCDN010000001_gene124 8.5e-133 380.0 COG3336@1|root,COG3336@2|Bacteria,1TQFK@1239|Firmicutes,4H9WN@91061|Bacilli,1ZBC8@1386|Bacillus 91061|Bacilli S cytochrome c oxidase ctaG - - ko:K02862 - - - - ko00000 - - - Caa3_CtaG k141_34392_1 1294265.JCM21738_1052 2.53e-119 348.0 COG0791@1|root,COG1388@1|root,COG0791@2|Bacteria,COG1388@2|Bacteria,1TP24@1239|Firmicutes,4HA77@91061|Bacilli,1ZCHY@1386|Bacillus 91061|Bacilli M COG1388 FOG LysM repeat - - - ko:K19220,ko:K19224 - - - - ko00000,ko01000,ko01002,ko01011 - CBM50 - LysM,NLPC_P60 k141_36518_1 1036674.A28LD_1719 6.89e-71 239.0 COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,1RMRN@1236|Gammaproteobacteria,2QF18@267893|Idiomarinaceae 1236|Gammaproteobacteria F Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate purL GO:0000166,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006520,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016874,GO:0016879,GO:0016884,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - iECH74115_1262.ECH74115_3792,iECO111_1330.ECO111_3283,iECSP_1301.ECSP_3501,iECs_1301.ECs3423,iG2583_1286.G2583_3088,iJN746.PP_1037,ic_1306.c3080 AIRS_C,GATase_5 k141_3408_1 218284.CCDN010000002_gene2915 5.18e-51 175.0 COG0661@1|root,COG0661@2|Bacteria,1TPIV@1239|Firmicutes,4HBW3@91061|Bacilli,1ZBPH@1386|Bacillus 91061|Bacilli S ABC1 family ubiB - - - - - - - - - - - ABC1,APH,RIO1 k141_3408_3 218284.CCDN010000002_gene2912 4.32e-55 173.0 COG3695@1|root,COG3695@2|Bacteria,1VC8H@1239|Firmicutes,4HKXS@91061|Bacilli,1ZI3E@1386|Bacillus 91061|Bacilli L 6-O-methylguanine DNA methyltransferase, DNA binding domain MGMT - - ko:K07443 - - - - ko00000 - - - DNA_binding_1 k141_2189_1 1294265.JCM21738_2289 2.04e-171 481.0 COG1295@1|root,COG1295@2|Bacteria,1U7HM@1239|Firmicutes,4H9MJ@91061|Bacilli,1ZCAD@1386|Bacillus 91061|Bacilli S Belongs to the UPF0761 family - - - ko:K07058 - - - - ko00000 - - - Virul_fac_BrkB k141_29682_1 1453501.JELR01000001_gene3064 1.17e-55 177.0 28H8Z@1|root,2Z7KS@2|Bacteria,1MW9T@1224|Proteobacteria,1RQV1@1236|Gammaproteobacteria,465P3@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF1282) - - - - - - - - - - - - DUF1282 k141_36519_2 1453501.JELR01000001_gene2433 1.99e-50 165.0 COG3148@1|root,COG3148@2|Bacteria,1MZCN@1224|Proteobacteria,1S977@1236|Gammaproteobacteria,468UJ@72275|Alteromonadaceae 1236|Gammaproteobacteria S DTW - - - ko:K05812 - - - - ko00000 - - - DTW k141_34394_1 1453501.JELR01000002_gene1088 1.24e-79 248.0 COG0026@1|root,COG0026@2|Bacteria,1MU70@1224|Proteobacteria,1RQEI@1236|Gammaproteobacteria,46573@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) purK GO:0000166,GO:0003674,GO:0003824,GO:0004638,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0016874,GO:0016879,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034028,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.4.18 ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07404 RC01927 ko00000,ko00001,ko00002,ko01000 - - iECUMN_1333.ECUMN_0562,iYL1228.KPN_00477 ATP-grasp k141_16545_1 398578.Daci_2652 6.68e-62 196.0 COG1670@1|root,COG1670@2|Bacteria,1RCX2@1224|Proteobacteria,2VQS6@28216|Betaproteobacteria,4ADRV@80864|Comamonadaceae 28216|Betaproteobacteria J PFAM GCN5-related N-acetyltransferase - - - - - - - - - - - - Acetyltransf_3 k141_28232_1 207954.MED92_11069 2.01e-64 201.0 COG1418@1|root,COG1418@2|Bacteria,1RJ5U@1224|Proteobacteria,1SAZE@1236|Gammaproteobacteria,1XPKV@135619|Oceanospirillales 135619|Oceanospirillales S mRNA catabolic process - - - - - - - - - - - - - k141_28232_2 1453501.JELR01000005_gene1697 3.58e-157 462.0 COG4247@1|root,COG4247@2|Bacteria,1MVTA@1224|Proteobacteria,1RQXH@1236|Gammaproteobacteria,46571@72275|Alteromonadaceae 1236|Gammaproteobacteria I Phytase phy - 3.1.3.8 ko:K01083 ko00562,map00562 - R03371 RC00078 ko00000,ko00001,ko01000 - - - Phytase k141_10630_1 340099.Teth39_0649 1.87e-05 50.8 COG1120@1|root,COG1120@2|Bacteria,1TP2Q@1239|Firmicutes,24CES@186801|Clostridia,42F48@68295|Thermoanaerobacterales 186801|Clostridia P PFAM ABC transporter related - - 3.6.3.34 ko:K02013 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 - - ABC_tran k141_3410_1 643648.Slip_0709 1.31e-81 255.0 COG0536@1|root,COG0536@2|Bacteria,1TPX7@1239|Firmicutes,247SP@186801|Clostridia,42JSC@68298|Syntrophomonadaceae 186801|Clostridia S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control obg - - ko:K03979 - - - - ko00000,ko01000,ko03009 - - - DUF1967,GTP1_OBG,MMR_HSR1 k141_30525_1 1453501.JELR01000002_gene197 1.17e-88 277.0 COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,1RNIT@1236|Gammaproteobacteria,464TD@72275|Alteromonadaceae 1236|Gammaproteobacteria G Belongs to the GPI family pgi GO:0003674,GO:0003824,GO:0004347,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033554,GO:0034404,GO:0034599,GO:0034641,GO:0034654,GO:0034655,GO:0042221,GO:0042802,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0055086,GO:0070887,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 - - iEcSMS35_1347.EcSMS35_4486 PGI k141_15236_2 1279017.AQYJ01000028_gene2502 1.57e-77 239.0 COG0576@1|root,COG0576@2|Bacteria,1RH8T@1224|Proteobacteria,1S5W5@1236|Gammaproteobacteria,467BX@72275|Alteromonadaceae 1236|Gammaproteobacteria O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ grpE GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0017076,GO:0019904,GO:0022607,GO:0030234,GO:0030554,GO:0032991,GO:0036094,GO:0042802,GO:0042803,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0050790,GO:0050896,GO:0051082,GO:0060589,GO:0060590,GO:0065003,GO:0065007,GO:0065009,GO:0071840,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - ko:K03687 - - - - ko00000,ko03029,ko03110 - - - GrpE k141_2192_1 1120983.KB894575_gene595 7.34e-80 257.0 COG1523@1|root,COG1523@2|Bacteria,1MU19@1224|Proteobacteria,2TRVS@28211|Alphaproteobacteria,1JN9G@119043|Rhodobiaceae 28211|Alphaproteobacteria G Carbohydrate-binding module 48 (Isoamylase N-terminal domain) glgX - 3.2.1.196,3.2.1.68 ko:K01214,ko:K02438 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02111,R09995,R11261 - ko00000,ko00001,ko00002,ko01000 - CBM48,GH13 - Alpha-amylase,CBM_48 k141_28234_1 218284.CCDN010000002_gene2138 3.1e-153 439.0 COG3844@1|root,COG3844@2|Bacteria,1TQ8V@1239|Firmicutes,4HBE8@91061|Bacilli,1ZBCN@1386|Bacillus 91061|Bacilli E Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively kynU GO:0003674,GO:0003824,GO:0016787,GO:0016822,GO:0016823,GO:0030429 3.7.1.3 ko:K01556 ko00380,ko01100,map00380,map01100 M00038 R00987,R02668,R03936 RC00284,RC00415 ko00000,ko00001,ko00002,ko01000 - - - Aminotran_5 k141_10632_1 1196031.ALEG01000039_gene1129 6.65e-07 50.1 COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,4HCH3@91061|Bacilli,1ZAXG@1386|Bacillus 91061|Bacilli I Belongs to the enoyl-CoA hydratase isomerase family yngF - - - - - - - - - - - ECH_1 k141_10632_2 218284.CCDN010000005_gene3202 1.9e-41 139.0 COG0662@1|root,COG0662@2|Bacteria,1U8MW@1239|Firmicutes,4IIJV@91061|Bacilli,1ZNPR@1386|Bacillus 91061|Bacilli G Cupin 2, conserved barrel domain protein - - - - - - - - - - - - - k141_30526_1 1294265.JCM21738_2323 1.37e-113 330.0 COG1167@1|root,COG1167@2|Bacteria,1TPS5@1239|Firmicutes,4HB1C@91061|Bacilli,1ZASA@1386|Bacillus 91061|Bacilli K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs ydfD - - ko:K18907 - M00700,M00702 - - ko00000,ko00002,ko01504,ko03000 - - - Aminotran_1_2,GntR k141_33128_1 1116375.VEJY3_23911 1.17e-35 131.0 COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,1RP0C@1236|Gammaproteobacteria,1XW4I@135623|Vibrionales 135623|Vibrionales E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - 2.6.1.18 ko:K00822 ko00280,ko00410,ko00640,ko01100,map00280,map00410,map00640,map01100 - R00907,R04187 RC00008,RC00062,RC00160 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_3 k141_33128_2 1116375.VEJY3_23906 0.0 958.0 COG1012@1|root,COG1012@2|Bacteria,1MUHV@1224|Proteobacteria,1RNFN@1236|Gammaproteobacteria,1XVHX@135623|Vibrionales 135623|Vibrionales C Aldehyde dehydrogenase family - - 1.2.1.18,1.2.1.27 ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 M00013 R00705,R00706,R00922,R00935 RC00004,RC02723,RC02817 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_33128_3 491952.Mar181_0240 1.41e-114 338.0 COG1737@1|root,COG1737@2|Bacteria,1R4PS@1224|Proteobacteria,1RQTN@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator - - - - - - - - - - - - HTH_6 k141_33128_4 491952.Mar181_0239 2.87e-188 530.0 COG0687@1|root,COG0687@2|Bacteria,1MW4Q@1224|Proteobacteria,1RPSC@1236|Gammaproteobacteria,1XS3E@135619|Oceanospirillales 135619|Oceanospirillales E Required for the activity of the bacterial periplasmic transport system of putrescine - - - ko:K11069 ko02010,map02010 M00299 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 - - SBP_bac_8 k141_33128_5 717774.Marme_1601 1.58e-139 408.0 COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,1RNPX@1236|Gammaproteobacteria,1XI1W@135619|Oceanospirillales 135619|Oceanospirillales E Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system - - 3.6.3.31 ko:K11072 ko02010,map02010 M00299 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.11.1 - - ABC_tran,TOBE_2 k141_33128_6 491952.Mar181_0237 1.54e-108 320.0 COG1176@1|root,COG1176@2|Bacteria,1MVGM@1224|Proteobacteria,1RNNZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria P ABC-type spermidine putrescine transport system, permease component I - - - ko:K11071 ko02010,map02010 M00299 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 - - BPD_transp_1 k141_2193_1 935836.JAEL01000023_gene1549 1.61e-72 237.0 COG0674@1|root,COG1013@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,1TPF0@1239|Firmicutes,4HCVY@91061|Bacilli,1ZBTS@1386|Bacillus 91061|Bacilli C COG0674 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, alpha subunit porA - 1.2.7.1 ko:K00169 ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200 M00173,M00307,M00374,M00620 R01196,R01199,R08034 RC00004,RC00250,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - PFOR_II,POR_N,TPP_enzyme_C k141_2193_2 649639.Bcell_2177 4.52e-36 130.0 COG1014@1|root,COG1144@1|root,COG1014@2|Bacteria,COG1144@2|Bacteria,1TRFJ@1239|Firmicutes,4HBXC@91061|Bacilli,1ZC2D@1386|Bacillus 91061|Bacilli C COG1014 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, gamma subunit porG - 1.2.7.1 ko:K00172 ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200 M00173,M00307,M00374,M00620 R01196,R01199,R08034 RC00004,RC00250,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - Fer4,Fer4_7,POR k141_29687_1 1042377.AFPJ01000005_gene2470 2.65e-111 333.0 COG4783@1|root,COG4783@2|Bacteria,1QUMJ@1224|Proteobacteria,1T2RP@1236|Gammaproteobacteria,4660W@72275|Alteromonadaceae 1236|Gammaproteobacteria S Zn-dependent protease, contains TPR repeats - - - - - - - - - - - - Peptidase_M48,TPR_16,TPR_2,TPR_8 k141_16691_1 13690.CP98_01372 1.56e-62 209.0 COG3182@1|root,COG3182@2|Bacteria,1MVET@1224|Proteobacteria,2TVHW@28211|Alphaproteobacteria,2K0UQ@204457|Sphingomonadales 204457|Sphingomonadales S PepSY-associated TM region - - - - - - - - - - - - PepSY_TM k141_22679_1 218284.CCDN010000006_gene3514 2.37e-113 347.0 COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1TR8J@1239|Firmicutes,4H9XN@91061|Bacilli,1ZATV@1386|Bacillus 91061|Bacilli I 3-hydroxyacyl-CoA dehydrogenase fadN - 1.1.1.35 ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 M00087 R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU32840 3HCDH,3HCDH_N,ECH_1 k141_2471_1 311403.Arad_2508 1.39e-86 274.0 COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,2TRC2@28211|Alphaproteobacteria,4B8KC@82115|Rhizobiaceae 28211|Alphaproteobacteria I propionyl-CoA carboxylase pccA GO:0003674,GO:0003824,GO:0004658,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009374,GO:0009987,GO:0016421,GO:0016874,GO:0016885,GO:0017144,GO:0019752,GO:0019842,GO:0019899,GO:0031406,GO:0031974,GO:0032787,GO:0033218,GO:0033293,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0070013,GO:0071704,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901681 6.4.1.3 ko:K01965 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 M00373,M00741 R01859 RC00097,RC00609 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2 k141_30992_1 1136417.AZWE01000003_gene3472 1.01e-19 89.0 COG3764@1|root,COG3764@2|Bacteria,2IFPY@201174|Actinobacteria,4DCW1@85008|Micromonosporales 201174|Actinobacteria M peptidase C60 sortase A and B - - - - - - - - - - - - Sortase k141_33357_1 1042377.AFPJ01000054_gene1683 9.39e-71 215.0 COG3245@1|root,COG3245@2|Bacteria,1MZBZ@1224|Proteobacteria,1S9Z9@1236|Gammaproteobacteria,467R4@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG3245 Cytochrome c5 cyc - 1.9.3.1 ko:K02277 ko00190,ko01100,map00190,map01100 M00155 - - ko00000,ko00001,ko00002,ko01000 3.D.4.4 - - Cytochrome_CBB3 k141_15545_2 1340434.AXVA01000014_gene582 6.12e-23 90.5 2DJQF@1|root,306WX@2|Bacteria,1U0IF@1239|Firmicutes,4I9X1@91061|Bacilli,1ZJCB@1386|Bacillus 91061|Bacilli S YfhD-like protein yfhD - - - - - - - - - - - YfhD k141_15545_3 218284.CCDN010000002_gene2920 8.68e-12 64.7 COG1090@1|root,COG1090@2|Bacteria,1TRCE@1239|Firmicutes,4HBRT@91061|Bacilli,1ZBKW@1386|Bacillus 91061|Bacilli S nucleoside-diphosphate sugar epimerase yfhF - - ko:K07071 - - - - ko00000 - - - DUF1731,Epimerase k141_23826_1 1034347.CAHJ01000037_gene4289 8.53e-54 169.0 COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,4HKF2@91061|Bacilli,1ZH48@1386|Bacillus 91061|Bacilli L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions hbs GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009889,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2001141 - ko:K03530 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding k141_9575_1 42565.FP66_06430 8.37e-67 204.0 COG0690@1|root,COG0690@2|Bacteria,1RDI9@1224|Proteobacteria,1S3PA@1236|Gammaproteobacteria,1XKF5@135619|Oceanospirillales 135619|Oceanospirillales U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation secE - - ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecE k141_32154_1 1116375.VEJY3_14400 9.35e-302 827.0 COG0471@1|root,COG0471@2|Bacteria,1R6QF@1224|Proteobacteria,1RQIG@1236|Gammaproteobacteria,1XTZX@135623|Vibrionales 135623|Vibrionales P COG0471 Di- and tricarboxylate transporters - - - ko:K14445 - - - - ko00000,ko02000 2.A.47.1 - - Na_sulph_symp k141_34553_2 218284.CCDN010000001_gene233 1.75e-260 721.0 COG0165@1|root,COG0165@2|Bacteria,1TNZ6@1239|Firmicutes,4HB24@91061|Bacilli,1ZD3C@1386|Bacillus 91061|Bacilli E argininosuccinate lyase argH GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01086 RC00445,RC00447 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ASL_C2,Lyase_1 k141_20262_1 218284.CCDN010000005_gene3365 4.45e-202 573.0 COG1032@1|root,COG1032@2|Bacteria,1TPGT@1239|Firmicutes,4HA0Y@91061|Bacilli,1ZAU7@1386|Bacillus 91061|Bacilli C Fe-S oxidoreductase bchE - 1.21.98.3 ko:K04034 ko00860,ko01100,ko01110,map00860,map01100,map01110 - R06268,R06269,R06270 RC00741,RC01491,RC01492 ko00000,ko00001,ko01000 - - - B12-binding,DUF4080,Radical_SAM k141_36899_1 1116375.VEJY3_05925 0.0 1005.0 COG0577@1|root,COG0577@2|Bacteria,1MVCT@1224|Proteobacteria,1RNP1@1236|Gammaproteobacteria,1XUDJ@135623|Vibrionales 135623|Vibrionales V ABC-type antimicrobial peptide transport system, permease component - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD k141_36899_2 1116375.VEJY3_05930 2.54e-233 646.0 COG5621@1|root,COG5621@2|Bacteria,1MUVF@1224|Proteobacteria,1RZ65@1236|Gammaproteobacteria,1XTRT@135623|Vibrionales 135623|Vibrionales S secreted hydrolase - - - - - - - - - - - - CrtC,Lipocalin_9 k141_36899_3 1116375.VEJY3_05935 3.88e-247 682.0 COG3004@1|root,COG3004@2|Bacteria,1MW15@1224|Proteobacteria,1RNDE@1236|Gammaproteobacteria,1XT58@135623|Vibrionales 135623|Vibrionales P ) H( ) antiporter that extrudes sodium in exchange for external protons nhaA GO:0003674,GO:0005215,GO:0005451,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015491,GO:0015672,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0035725,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0098655,GO:0098660,GO:0098662,GO:0099516,GO:1902600 - ko:K03313 - - - - ko00000,ko02000 2.A.33.1 - - Na_H_antiport_1 k141_36899_4 1219076.N646_0265 1.27e-133 380.0 COG1309@1|root,COG1309@2|Bacteria,1RDIM@1224|Proteobacteria,1S401@1236|Gammaproteobacteria,1XUJ5@135623|Vibrionales 135623|Vibrionales K Transcriptional regulator - - - - - - - - - - - - TetR_N k141_36899_5 1116375.VEJY3_05945 0.0 1454.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RPM5@1236|Gammaproteobacteria,1XT9R@135623|Vibrionales 135623|Vibrionales I COG1960 Acyl-CoA dehydrogenases - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,DUF1974 k141_36899_6 1219076.N646_0267 3.58e-281 769.0 COG3007@1|root,COG3007@2|Bacteria,1MWCQ@1224|Proteobacteria,1RPPP@1236|Gammaproteobacteria,1XUMI@135623|Vibrionales 135623|Vibrionales I Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP) fabV GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050343,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.3.1.44,1.3.1.9 ko:K00209 ko00061,ko00650,ko01100,ko01120,ko01200,ko01212,map00061,map00650,map01100,map01120,map01200,map01212 M00083 R01171,R04429,R04724,R04955,R04958,R04961,R04966,R04969 RC00052,RC00076 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Eno-Rase_FAD_bd,Eno-Rase_NADH_b,Enoyl_reductase k141_36899_7 1116375.VEJY3_05955 0.0 1043.0 COG2985@1|root,COG3273@1|root,COG2985@2|Bacteria,COG3273@2|Bacteria,1MUVM@1224|Proteobacteria,1RQ47@1236|Gammaproteobacteria,1XSX8@135623|Vibrionales 135623|Vibrionales P transport protein ybjL - - ko:K07085 - - - - ko00000 2.A.81 - - Asp-Al_Ex,TrkA_C k141_36899_8 1116375.VEJY3_05960 3.95e-61 187.0 COG0695@1|root,COG0695@2|Bacteria,1RGZ7@1224|Proteobacteria,1S5ZP@1236|Gammaproteobacteria,1XXU0@135623|Vibrionales 135623|Vibrionales O COG0695 Glutaredoxin and related proteins grxA - - ko:K03674 - - - - ko00000,ko03110 - - - Glutaredoxin k141_36899_9 223926.28806223 3.38e-262 723.0 COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,1S1W6@1236|Gammaproteobacteria,1XTZE@135623|Vibrionales 135623|Vibrionales C alcohol dehydrogenase - - - - - - - - - - - - Fe-ADH k141_36899_10 1280001.BAOA01000019_gene402 2.71e-197 547.0 COG1737@1|root,COG1737@2|Bacteria,1MV3U@1224|Proteobacteria,1RNC4@1236|Gammaproteobacteria,1XSSF@135623|Vibrionales 135623|Vibrionales K COG1737 Transcriptional regulators hexR - - ko:K19337 - - - - ko00000,ko03000 - - - HTH_6,SIS k141_34568_1 1042377.AFPJ01000005_gene2463 3.42e-19 84.3 COG4665@1|root,COG4665@2|Bacteria,1RHBW@1224|Proteobacteria,1S5Y0@1236|Gammaproteobacteria,467SF@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Tripartite ATP-independent periplasmic transporters, DctQ component gtrA - - - - - - - - - - - DctQ k141_26253_1 1279017.AQYJ01000023_gene3188 2.79e-228 655.0 COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,1RNEB@1236|Gammaproteobacteria,465F9@72275|Alteromonadaceae 1236|Gammaproteobacteria J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner valS GO:0000287,GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006417,GO:0006418,GO:0006438,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0034248,GO:0034250,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045903,GO:0046483,GO:0046872,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0052689,GO:0060255,GO:0061475,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:2000112 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iECH74115_1262.ECH74115_5779,iECNA114_1301.ECNA114_4481,iECO26_1355.ECO26_5428,iECSP_1301.ECSP_5359,iECs_1301.ECs5235,iG2583_1286.G2583_5088,iJN746.PP_0977,iSBO_1134.SBO_4182,iSSON_1240.SSON_4443,iYL1228.KPN_04663,iZ_1308.Z5870 Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 k141_29796_2 218284.CCDN010000001_gene959 5.15e-75 231.0 2E6BB@1|root,330Z5@2|Bacteria,1VF3M@1239|Firmicutes,4HH7J@91061|Bacilli,1ZEMQ@1386|Bacillus 91061|Bacilli S stage III sporulation protein AG spoIIIAG - - ko:K06396 - - - - ko00000 - - - - k141_15559_1 441769.ABFU01000043_gene3398 5.9e-37 139.0 COG0840@1|root,COG0840@2|Bacteria,1TZ8Z@1239|Firmicutes,4HBMM@91061|Bacilli,1ZDNK@1386|Bacillus 91061|Bacilli NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). mcp4 - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal k141_13191_1 1279017.AQYJ01000027_gene1693 1.34e-227 632.0 COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,1RMXH@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Belongs to the RtcB family rtcB GO:0003674,GO:0003824,GO:0003909,GO:0005488,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006396,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008452,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0030145,GO:0033554,GO:0034641,GO:0042245,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:0140098,GO:1901360 6.5.1.3 ko:K14415 - - - - ko00000,ko01000,ko03016 - - - RtcB k141_13191_2 1279017.AQYJ01000027_gene1694 1.72e-127 377.0 COG4650@1|root,COG4650@2|Bacteria,1MX6U@1224|Proteobacteria,1RS3H@1236|Gammaproteobacteria 1236|Gammaproteobacteria K regulates genes involved in forming a 2',3'-cyclic phosphodiester on RNA rtcR GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - ko:K14414 - - - - ko00000,ko03000 - - - RtcR,Sigma54_activat k141_7206_1 1243664.CAVL020000019_gene3534 4.96e-27 105.0 COG1414@1|root,COG1414@2|Bacteria,1TRMW@1239|Firmicutes,4HCSI@91061|Bacilli,1ZDR0@1386|Bacillus 91061|Bacilli K Transcriptional regulator kipR - - ko:K13641 - - - - ko00000,ko03000 - - - HTH_IclR,IclR k141_7206_2 935836.JAEL01000007_gene2899 2.8e-119 346.0 COG0179@1|root,COG0179@2|Bacteria,1UZ6U@1239|Firmicutes,4HCE0@91061|Bacilli,1ZARQ@1386|Bacillus 91061|Bacilli Q Domain of unknown function (DUF2437) - - - - - - - - - - - - DUF2437,FAA_hydrolase k141_23836_1 616991.JPOO01000003_gene2629 2.31e-10 61.6 COG2170@1|root,COG2170@2|Bacteria,4NFFP@976|Bacteroidetes,1HZNS@117743|Flavobacteriia 976|Bacteroidetes S ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity ybdK - - ko:K06048 - - - - ko00000,ko01000 - - - GCS2 k141_21514_1 218284.CCDN010000001_gene1626 1.26e-78 234.0 COG0322@1|root,COG0322@2|Bacteria,1V8E6@1239|Firmicutes,4HJHV@91061|Bacilli,1ZGGU@1386|Bacillus 91061|Bacilli L COG0322 Nuclease subunit of the excinuclease complex yurQ GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - - - - - - - - - - GIY-YIG k141_1235_1 1056820.KB900656_gene3606 2.57e-222 647.0 COG4774@1|root,COG4774@2|Bacteria,1QXWU@1224|Proteobacteria,1T3IF@1236|Gammaproteobacteria,2PPD0@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec k141_16702_1 1453501.JELR01000001_gene1856 5e-58 184.0 COG0526@1|root,COG0526@2|Bacteria,1N726@1224|Proteobacteria,1SD4C@1236|Gammaproteobacteria,468P8@72275|Alteromonadaceae 1236|Gammaproteobacteria CO COG0526 Thiol-disulfide isomerase and thioredoxins resA - - - - - - - - - - - AhpC-TSA k141_14365_1 218284.CCDN010000001_gene1590 6.89e-183 521.0 COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,4HAMK@91061|Bacilli,1ZBB4@1386|Bacillus 91061|Bacilli E ABC transporter substrate-binding protein dppE GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 - ko:K16199 ko02010,map02010 M00566 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.2 - - SBP_bac_5 k141_26254_3 1460640.JCM19046_59 8.42e-11 65.9 COG3064@1|root,COG3064@2|Bacteria,1V588@1239|Firmicutes,4IU1H@91061|Bacilli 91061|Bacilli M Host cell surface-exposed lipoprotein - - - - - - - - - - - - Lipoprotein_Ltp k141_11963_2 1042377.AFPJ01000025_gene616 5.69e-05 45.1 COG1225@1|root,COG1225@2|Bacteria,1RD2X@1224|Proteobacteria,1S3TJ@1236|Gammaproteobacteria,4673G@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG0526 Thiol-disulfide isomerase and thioredoxins - - - - - - - - - - - - AhpC-TSA k141_34569_1 218284.CCDN010000001_gene1342 2.01e-200 566.0 COG0025@1|root,COG0025@2|Bacteria,1TR4G@1239|Firmicutes,4HBJR@91061|Bacilli,1ZQCF@1386|Bacillus 91061|Bacilli P Sodium/hydrogen exchanger family - - - ko:K03316 - - - - ko00000 2.A.36 - - Na_H_Exchanger k141_13192_1 1033739.CAEU01000018_gene2406 3.53e-31 118.0 COG0803@1|root,COG0803@2|Bacteria,1TPG7@1239|Firmicutes,4H9UN@91061|Bacilli,26DFA@186818|Planococcaceae 91061|Bacilli P Belongs to the bacterial solute-binding protein 9 family adcA - - ko:K09815,ko:K09818 ko02010,map02010 M00242,M00243 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 - - ZnuA k141_114_1 1042377.AFPJ01000052_gene1584 4.12e-128 391.0 COG1629@1|root,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria,4652I@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec k141_7207_2 218284.CCDN010000002_gene2668 1.75e-99 303.0 COG0659@1|root,COG0659@2|Bacteria,1TPI4@1239|Firmicutes,4H9V4@91061|Bacilli,1ZCKC@1386|Bacillus 91061|Bacilli P COG0659 Sulfate permease and related transporters (MFS superfamily) ybaR - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - STAS,Sulfate_transp k141_15561_1 218284.CCDN010000005_gene3220 3.8e-97 301.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1TR2N@1239|Firmicutes,4H9RR@91061|Bacilli,1ZB2Q@1386|Bacillus 91061|Bacilli EU peptidase yuxL - 3.4.19.1 ko:K01303 - - - - ko00000,ko01000,ko01002 - - - PD40,Peptidase_S9 k141_16703_2 218284.CCDN010000006_gene3546 1.38e-48 158.0 COG1846@1|root,COG1846@2|Bacteria,1V6G0@1239|Firmicutes,4HKQR@91061|Bacilli,1ZHB6@1386|Bacillus 91061|Bacilli K COG1846 Transcriptional regulators ohrR GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - - - - - - - - - - MarR k141_21515_1 218284.CCDN010000001_gene24 2.55e-103 334.0 COG1196@1|root,COG1196@2|Bacteria,1TPJV@1239|Firmicutes,4HB89@91061|Bacilli,1ZAWM@1386|Bacillus 91061|Bacilli D Required for chromosome condensation and partitioning smc GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K03529 - - - - ko00000,ko03036 - - - SMC_N,SMC_hinge k141_25027_2 1128421.JAGA01000002_gene426 5.23e-35 122.0 COG1917@1|root,COG1917@2|Bacteria,2NRCD@2323|unclassified Bacteria 2|Bacteria S Cupin 2, conserved barrel domain protein - - - - - - - - - - - - Cupin_2 k141_4854_1 1120792.JAFV01000001_gene753 7.73e-75 234.0 COG2070@1|root,COG2070@2|Bacteria,1MU0U@1224|Proteobacteria,2TS5U@28211|Alphaproteobacteria,36ZRY@31993|Methylocystaceae 28211|Alphaproteobacteria S Nitronate monooxygenase MA20_20575 - 1.13.12.16 ko:K00459 ko00910,map00910 - R00025 RC02541,RC02759 ko00000,ko00001,ko01000 - - - NMO k141_13193_1 218284.CCDN010000002_gene2533 3.21e-60 187.0 COG1695@1|root,COG1695@2|Bacteria,1V85H@1239|Firmicutes,4HJMF@91061|Bacilli,1ZH6V@1386|Bacillus 91061|Bacilli K Transcriptional regulator PadR-like family - - - - - - - - - - - - PadR k141_31012_1 1279017.AQYJ01000023_gene3160 1.97e-52 181.0 COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,1RPJB@1236|Gammaproteobacteria,466BN@72275|Alteromonadaceae 1236|Gammaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoN GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 ko:K00343 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_M k141_31012_2 1279017.AQYJ01000023_gene3159 8.88e-81 242.0 2EKB9@1|root,33E1N@2|Bacteria,1QQ1H@1224|Proteobacteria,1SVQ8@1236|Gammaproteobacteria,46CB7@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_31012_3 1279017.AQYJ01000023_gene3292 0.0 1738.0 COG3325@1|root,COG3979@1|root,COG3325@2|Bacteria,COG3979@2|Bacteria,1R3YZ@1224|Proteobacteria,1RY6I@1236|Gammaproteobacteria,46AA7@72275|Alteromonadaceae 1236|Gammaproteobacteria G Chitinase C - - 3.2.1.14,3.2.1.202 ko:K01183,ko:K21606 ko00520,ko01100,map00520,map01100 - R01206,R02334 RC00467 ko00000,ko00001,ko01000 - CBM5,GH18 - CBM_5_12_2,ChiC,Glyco_hydro_18 k141_116_1 1007103.AFHW01000028_gene1742 8.48e-27 111.0 COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,4HA3G@91061|Bacilli,26QWH@186822|Paenibacillaceae 91061|Bacilli T Diguanylate cyclase - - 2.7.7.65 ko:K21023 ko02025,map02025 - - - ko00000,ko00001,ko01000 - - - EAL,GGDEF,MHYT,PAS,PAS_4,PAS_9 k141_7209_1 720555.BATR1942_20360 2.21e-50 164.0 COG1714@1|root,COG1714@2|Bacteria,1V6N5@1239|Firmicutes,4HJRB@91061|Bacilli,1ZI28@1386|Bacillus 91061|Bacilli S membrane yckC - - - - - - - - - - - RDD k141_7209_2 933115.GPDM_12816 5.89e-29 109.0 COG0454@1|root,COG0456@2|Bacteria,1VFVQ@1239|Firmicutes,4HK5T@91061|Bacilli,26FYP@186818|Planococcaceae 91061|Bacilli K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10 k141_21517_1 1274524.BSONL12_02447 8.07e-26 102.0 COG4608@1|root,COG4608@2|Bacteria,1V005@1239|Firmicutes,4HD9V@91061|Bacilli,1ZC58@1386|Bacillus 91061|Bacilli E oligopeptide ABC transporter ATP-binding protein dppD - - ko:K02032 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - ABC_tran k141_21517_2 1218173.BALCAV_0201120 3.33e-29 112.0 COG0444@1|root,COG0444@2|Bacteria,1UZAI@1239|Firmicutes,4HE4X@91061|Bacilli,1ZDFE@1386|Bacillus 91061|Bacilli EP ATPases associated with a variety of cellular activities pstB7 - - ko:K02031 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - ABC_tran,oligo_HPY k141_16705_1 218284.CCDN010000001_gene83 6.55e-52 169.0 COG1589@1|root,COG1589@2|Bacteria,1V6V5@1239|Firmicutes,4HDFD@91061|Bacilli,1ZDSW@1386|Bacillus 91061|Bacilli D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex divIB - - ko:K03589 ko04112,map04112 - - - ko00000,ko00001,ko03036 - - - FtsQ,POTRA_1 k141_16705_2 218284.CCDN010000001_gene82 1.56e-20 87.4 COG3879@1|root,COG3879@2|Bacteria,1V0FG@1239|Firmicutes,4HAN4@91061|Bacilli,1ZE4Z@1386|Bacillus 91061|Bacilli S protein conserved in bacteria ylxW GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - - - - - - - - - - DUF881 k141_9589_1 1122201.AUAZ01000007_gene3634 5.43e-17 76.6 COG3529@1|root,COG3529@2|Bacteria,1NPXJ@1224|Proteobacteria,1SHB8@1236|Gammaproteobacteria,4696D@72275|Alteromonadaceae 1236|Gammaproteobacteria S nucleic-acid-binding protein containing a Zn-ribbon domain - - - ko:K07070 - - - - ko00000 - - - DUF2387 k141_9589_2 1279017.AQYJ01000027_gene1757 0.0 991.0 COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,1RMAH@1236|Gammaproteobacteria,4648F@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0339 Zn-dependent oligopeptidases prlC GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006465,GO:0006508,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0034645,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051604,GO:0070011,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564,GO:1901576 3.4.24.70 ko:K01414 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M3 k141_9589_3 1042377.AFPJ01000012_gene1376 1.22e-95 282.0 COG0663@1|root,COG0663@2|Bacteria,1RD76@1224|Proteobacteria,1RPB6@1236|Gammaproteobacteria,466EI@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily yrdA GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008270,GO:0009987,GO:0016043,GO:0022607,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071840 - - - - - - - - - - Hexapep k141_9589_4 28229.ND2E_0195 1.86e-65 213.0 COG2197@1|root,COG2197@2|Bacteria,1RJAM@1224|Proteobacteria,1S868@1236|Gammaproteobacteria 1236|Gammaproteobacteria K luxR family - - - - - - - - - - - - GerE k141_9589_5 28229.ND2E_4093 2.29e-234 657.0 COG0665@1|root,COG0665@2|Bacteria,1MVGP@1224|Proteobacteria,1RNJ9@1236|Gammaproteobacteria,2Q6GQ@267889|Colwelliaceae 1236|Gammaproteobacteria E PFAM FAD dependent oxidoreductase - - - - - - - - - - - - DAO k141_6056_1 1316932.MHH_c17920 1.26e-110 332.0 COG1783@1|root,COG1783@2|Bacteria,1R66A@1224|Proteobacteria,1RQFD@1236|Gammaproteobacteria,1Y9SI@135625|Pasteurellales 135625|Pasteurellales S Terminase RNAseH like domain - - - ko:K06909 - - - - ko00000 - - - Terminase_3,Terminase_3C k141_13194_1 218284.CCDN010000003_gene2979 6.2e-24 91.3 2E2ZT@1|root,32Y0E@2|Bacteria,1VEHE@1239|Firmicutes,4HNK8@91061|Bacilli,1ZITS@1386|Bacillus 91061|Bacilli S DNA topological change sspF - - ko:K06423 - - - - ko00000 - - - SASP k141_23837_1 1279017.AQYJ01000029_gene3863 7.54e-37 144.0 COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,1RMFJ@1236|Gammaproteobacteria,466DQ@72275|Alteromonadaceae 1236|Gammaproteobacteria H COG4206 Outer membrane cobalamin receptor protein btuB - - ko:K16092 - - - - ko00000,ko02000 1.B.14.3 - - Plug,TonB_dep_Rec k141_26257_1 1122194.AUHU01000010_gene3096 2.16e-44 164.0 COG3940@1|root,COG3940@2|Bacteria,1PDX5@1224|Proteobacteria,1RQ3B@1236|Gammaproteobacteria,465S6@72275|Alteromonadaceae 1236|Gammaproteobacteria G Ricin-type beta-trefoil lectin domain-like - - - - - - - - - - - - Glyco_hydro_43,RicinB_lectin_2 k141_9590_1 1123236.KB899384_gene2354 4.41e-95 283.0 COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,1RMGN@1236|Gammaproteobacteria,463XZ@72275|Alteromonadaceae 1236|Gammaproteobacteria E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate trpA GO:0000162,GO:0003674,GO:0003824,GO:0004834,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - iECED1_1282.ECED1_1467,iECP_1309.ECP_1308 Trp_syntA k141_6057_1 1347086.CCBA010000019_gene1031 1.24e-69 216.0 COG0454@1|root,COG0456@2|Bacteria,1V4RP@1239|Firmicutes,4HHSD@91061|Bacilli,1ZH0Q@1386|Bacillus 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10 k141_31013_2 1134474.O59_000628 1.39e-28 113.0 COG2433@1|root,COG2433@2|Bacteria,1N0ZS@1224|Proteobacteria,1SBFE@1236|Gammaproteobacteria,1FHAB@10|Cellvibrio 1236|Gammaproteobacteria S Pfam Transposase IS66 - - - - - - - - - - - - - k141_31013_3 1178482.BJB45_20110 5.59e-11 62.8 COG0461@1|root,COG0461@2|Bacteria,1MW6F@1224|Proteobacteria,1RQYG@1236|Gammaproteobacteria,1XHYH@135619|Oceanospirillales 135619|Oceanospirillales F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) pyrE - 2.4.2.10 ko:K00762 ko00240,ko01100,map00240,map01100 M00051 R01870 RC00611 ko00000,ko00001,ko00002,ko01000 - - - Pribosyltran k141_16706_1 218284.CCDN010000001_gene1893 2.91e-180 541.0 COG2176@1|root,COG2176@2|Bacteria,1TPAG@1239|Firmicutes,4H9RF@91061|Bacilli,1ZCIB@1386|Bacillus 91061|Bacilli L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity polC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.7.7 ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_a_NI,DNA_pol3_a_NII,DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon k141_117_1 218284.CCDN010000001_gene793 2.15e-128 367.0 COG0704@1|root,COG0704@2|Bacteria,1URN3@1239|Firmicutes,4HEU9@91061|Bacilli,1ZDDZ@1386|Bacillus 91061|Bacilli P Plays a role in the regulation of phosphate uptake phoU - - ko:K02039 - - - - ko00000 - - - PhoU k141_117_2 218284.CCDN010000001_gene792 7.69e-84 253.0 COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,4HAB1@91061|Bacilli,1ZBQ5@1386|Bacillus 91061|Bacilli P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system pstB - 3.6.3.27 ko:K02036 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 - iSB619.SA_RS06920 ABC_tran k141_26258_1 1453501.JELR01000001_gene2490 5.89e-61 208.0 COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,1RMS8@1236|Gammaproteobacteria,4657M@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) slt GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009274,GO:0016740,GO:0016757,GO:0030203,GO:0030288,GO:0030312,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - ko:K08309 - - - - ko00000,ko01000,ko01011 - GH23 iETEC_1333.ETEC_4747,iPC815.YPO0452 SLT,SLT_L k141_17953_1 218284.CCDN010000001_gene1334 4.92e-123 364.0 COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HAHB@91061|Bacilli,1ZPZR@1386|Bacillus 91061|Bacilli IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II yngI - - ko:K00666 - - - - ko00000,ko01000,ko01004 - - - AMP-binding,AMP-binding_C k141_6058_1 1196031.ALEG01000028_gene4159 6.47e-39 136.0 COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,4H9ZU@91061|Bacilli,1ZBBA@1386|Bacillus 91061|Bacilli G Aldolase fba - 4.1.2.13,4.1.2.29 ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01070,R01829,R02568,R05378 RC00438,RC00439,RC00603,RC00604,RC00721 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU39670 F_bP_aldolase k141_21518_1 1385513.N780_17315 1.08e-46 160.0 COG2066@1|root,COG2066@2|Bacteria,1TP64@1239|Firmicutes,4H9XA@91061|Bacilli,2Y9F9@289201|Pontibacillus 91061|Bacilli E Belongs to the glutaminase family glsA - 3.5.1.2 ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 - R00256,R01579 RC00010,RC02798 ko00000,ko00001,ko01000 - - - Glutaminase k141_21518_2 218284.CCDN010000001_gene1672 3.41e-99 293.0 COG0546@1|root,COG0546@2|Bacteria,1V4W6@1239|Firmicutes,4HGEW@91061|Bacilli,1ZQ6Z@1386|Bacillus 91061|Bacilli S haloacid dehalogenase-like hydrolase - - 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 - R01334 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 k141_14367_1 218284.CCDN010000001_gene1888 5.74e-116 353.0 COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,4HA8S@91061|Bacilli,1ZBWA@1386|Bacillus 91061|Bacilli J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,IF-2,IF2_N k141_3668_1 1116375.VEJY3_18296 6.39e-31 120.0 COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,1RNKA@1236|Gammaproteobacteria 1236|Gammaproteobacteria H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses nadE - 6.3.1.5,6.3.5.1 ko:K01916,ko:K01950 ko00760,ko01100,map00760,map01100 M00115 R00189,R00257 RC00010,RC00100 ko00000,ko00001,ko00002,ko01000 - - - CN_hydrolase,NAD_synthase k141_3668_2 268407.PWYN_16725 7.84e-19 85.1 2CAVT@1|root,30IPH@2|Bacteria,1UPWP@1239|Firmicutes,4IVCD@91061|Bacilli,277UU@186822|Paenibacillaceae 91061|Bacilli S Protein of unknown function (DUF2798) - - - - - - - - - - - - DUF2798 k141_3668_3 1196322.A370_00828 2.36e-23 95.9 COG1846@1|root,COG1846@2|Bacteria,1VHA8@1239|Firmicutes,24KDV@186801|Clostridia,36K4R@31979|Clostridiaceae 186801|Clostridia K Winged helix-turn-helix DNA-binding - - - - - - - - - - - - HTH_24,HTH_27,MarR_2 k141_3668_4 326442.PSHAa2703 2.85e-40 168.0 COG1629@1|root,COG4771@2|Bacteria,1MXAE@1224|Proteobacteria,1RWWH@1236|Gammaproteobacteria 1236|Gammaproteobacteria P receptor - - - - - - - - - - - - Plug,TonB_dep_Rec k141_28840_1 1116375.VEJY3_13525 1.14e-273 763.0 COG0840@1|root,COG4564@1|root,COG0840@2|Bacteria,COG4564@2|Bacteria,1MU9B@1224|Proteobacteria,1RQI8@1236|Gammaproteobacteria,1XTYN@135623|Vibrionales 135623|Vibrionales NT methyl-accepting chemotaxis protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - MCPsignal,sCache_2 k141_19237_1 1116375.VEJY3_12590 3.62e-228 632.0 COG1015@1|root,COG1015@2|Bacteria,1MVN8@1224|Proteobacteria,1RQ6W@1236|Gammaproteobacteria,1XU6Q@135623|Vibrionales 135623|Vibrionales G Phosphotransfer between the C1 and C5 carbon atoms of pentose deoB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008973,GO:0009987,GO:0016853,GO:0016866,GO:0016868,GO:0034641,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360 5.4.2.7 ko:K01839 ko00030,ko00230,map00030,map00230 - R01057,R02749 RC00408 ko00000,ko00001,ko01000 - - - Metalloenzyme k141_19237_2 1280001.BAOA01000059_gene2253 2.13e-167 468.0 COG0813@1|root,COG0813@2|Bacteria,1MUW6@1224|Proteobacteria,1RMMA@1236|Gammaproteobacteria,1XUQM@135623|Vibrionales 135623|Vibrionales F phosphorylase deoD GO:0003674,GO:0003824,GO:0004731,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0034641,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:1901360 2.4.2.1 ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244 RC00033,RC00063,RC00122 ko00000,ko00001,ko01000 - - - PNP_UDP_1 k141_19237_3 1116375.VEJY3_12580 1.73e-120 346.0 COG3726@1|root,COG3726@2|Bacteria,1MUT6@1224|Proteobacteria,1RNHZ@1236|Gammaproteobacteria,1XT32@135623|Vibrionales 135623|Vibrionales S membrane protein affecting hemolysin expression smp - - ko:K07186 - - - - ko00000 - - - SMP_2 k141_19237_4 1116375.VEJY3_12575 3.57e-214 593.0 COG0560@1|root,COG0560@2|Bacteria,1MWA3@1224|Proteobacteria,1RNJE@1236|Gammaproteobacteria,1XTII@135623|Vibrionales 135623|Vibrionales E phosphoserine phosphatase serB GO:0001505,GO:0003674,GO:0003824,GO:0004647,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006563,GO:0006564,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0017144,GO:0019752,GO:0042133,GO:0042136,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.3 ko:K01079 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R00582 RC00017 ko00000,ko00001,ko00002,ko01000,ko01009 - - - HAD,Hydrolase k141_19237_5 223926.28807428 0.0 1233.0 2C5UW@1|root,2Z80T@2|Bacteria,1MXH2@1224|Proteobacteria,1RR1H@1236|Gammaproteobacteria,1XU04@135623|Vibrionales 135623|Vibrionales S PilZ domain - - - - - - - - - - - - PilZ k141_19237_6 223926.28807427 0.0 876.0 COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,1RN2E@1236|Gammaproteobacteria,1XSUR@135623|Vibrionales 135623|Vibrionales O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function radA - - ko:K04485 - - - - ko00000,ko03400 - - - AAA_25,ATPase,ChlI k141_19237_7 796620.VIBC2010_10661 0.0 1327.0 COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,1RNNJ@1236|Gammaproteobacteria,1XTQW@135623|Vibrionales 135623|Vibrionales J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome fusA2 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02355 - - - - ko00000,ko03012,ko03029 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 k141_19237_8 1116375.VEJY3_12555 6.6e-214 592.0 COG0583@1|root,COG0583@2|Bacteria,1RG9S@1224|Proteobacteria,1S4W4@1236|Gammaproteobacteria,1XSVI@135623|Vibrionales 135623|Vibrionales K Bacterial regulatory helix-turn-helix protein, lysR family - - - ko:K03566 ko02026,map02026 - - - ko00000,ko00001,ko03000 - - - HTH_1,LysR_substrate k141_15725_1 218284.CCDN010000002_gene2158 1.08e-153 441.0 COG1653@1|root,COG1653@2|Bacteria,1TQ0V@1239|Firmicutes,4HA7Z@91061|Bacilli,1ZF6A@1386|Bacillus 91061|Bacilli G ABC transporter substrate-binding protein - - - - - - - - - - - - SBP_bac_1,SBP_bac_8 k141_4964_1 218284.CCDN010000001_gene197 4.14e-125 364.0 COG0598@1|root,COG0598@2|Bacteria,1TPSV@1239|Firmicutes,4HAPC@91061|Bacilli,1ZBVW@1386|Bacillus 91061|Bacilli P Mediates influx of magnesium ions corA - - ko:K03284 - - - - ko00000,ko02000 1.A.35.1,1.A.35.3 - - CorA k141_34723_1 42565.FP66_13725 5.25e-119 350.0 COG2031@1|root,COG2031@2|Bacteria,1MV5A@1224|Proteobacteria,1RMTZ@1236|Gammaproteobacteria,1XIXY@135619|Oceanospirillales 135619|Oceanospirillales I fatty acid transporter - - - ko:K02106 ko02020,map02020 - - - ko00000,ko00001 2.A.73.1 - - SCFA_trans k141_14519_1 861299.J421_4471 2.48e-77 251.0 COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,1ZT89@142182|Gemmatimonadetes 142182|Gemmatimonadetes C Transketolase, pyrimidine binding domain - - 1.2.4.4 ko:K11381 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 M00036 R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00027,RC00627,RC02743,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh,Transket_pyr,Transketolase_C k141_33512_1 1121403.AUCV01000004_gene2026 2.96e-30 119.0 COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,42S2A@68525|delta/epsilon subdivisions,2WMQ8@28221|Deltaproteobacteria,2MJAD@213118|Desulfobacterales 28221|Deltaproteobacteria NOU Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue pilD - 3.4.23.43 ko:K02654 - M00331 - - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 3.A.15.2 - - DiS_P_DiS,Peptidase_A24 k141_10928_1 1042377.AFPJ01000028_gene2210 2.92e-162 489.0 COG0834@1|root,COG4623@1|root,COG0834@2|Bacteria,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,1RM8W@1236|Gammaproteobacteria,467JF@72275|Alteromonadaceae 1236|Gammaproteobacteria EMT Bacterial periplasmic substrate-binding proteins - GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - ko:K18691 - - - - ko00000,ko01000,ko01011 - - - SBP_bac_3,SLT k141_10928_2 1279017.AQYJ01000022_gene2624 2e-115 336.0 COG3226@1|root,COG3226@2|Bacteria,1NNVA@1224|Proteobacteria,1S6UQ@1236|Gammaproteobacteria,46BE5@72275|Alteromonadaceae 1236|Gammaproteobacteria K protein conserved in bacteria - - - - - - - - - - - - TetR_C_6,TetR_N k141_10928_3 1279017.AQYJ01000022_gene2625 1.33e-144 410.0 COG4660@1|root,COG4660@2|Bacteria,1MW6N@1224|Proteobacteria,1RMEH@1236|Gammaproteobacteria,464BB@72275|Alteromonadaceae 1236|Gammaproteobacteria C Part of a membrane complex involved in electron transport rnfE GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016021,GO:0016491,GO:0016651,GO:0031224,GO:0044425,GO:0044464,GO:0055114,GO:0071944 - ko:K03613 - - - - ko00000 - - - Rnf-Nqr k141_10928_4 1453501.JELR01000001_gene3227 2.26e-56 181.0 COG4659@1|root,COG4659@2|Bacteria,1RDEP@1224|Proteobacteria,1RPAD@1236|Gammaproteobacteria,4672J@72275|Alteromonadaceae 1236|Gammaproteobacteria C Part of a membrane complex involved in electron transport rnfG - - ko:K03612 - - - - ko00000 - - - FMN_bind k141_16901_1 314285.KT71_11675 1.61e-141 430.0 COG3544@1|root,COG3544@2|Bacteria,1NTI3@1224|Proteobacteria,1T0HG@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF4142) - - - - - - - - - - - - DUF305 k141_16901_2 1453501.JELR01000005_gene1601 6.69e-124 362.0 COG2819@1|root,COG2819@2|Bacteria,1QNQ2@1224|Proteobacteria,1TANG@1236|Gammaproteobacteria,46A9U@72275|Alteromonadaceae 1236|Gammaproteobacteria S Putative esterase - - - - - - - - - - - - Esterase k141_12196_1 218284.CCDN010000005_gene3254 1.25e-210 593.0 COG0446@1|root,COG0446@2|Bacteria,1TPWW@1239|Firmicutes,4HA11@91061|Bacilli,1ZATE@1386|Bacillus 91061|Bacilli P Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain cdr - 1.8.1.14 ko:K08255 - - - - ko00000,ko01000 - - - Pyr_redox_2,Pyr_redox_dim,Rhodanese,TusA k141_12196_2 665952.HMPREF1015_01610 3.01e-68 211.0 COG1666@1|root,COG1666@2|Bacteria,1V3UR@1239|Firmicutes,4HHVD@91061|Bacilli,1ZFPU@1386|Bacillus 91061|Bacilli S Belongs to the UPF0234 family yitK - - ko:K09767 - - - - ko00000 - - - DUF520 k141_12196_3 1117379.BABA_20416 2.54e-17 73.6 29AUJ@1|root,2ZXTW@2|Bacteria,1W3EK@1239|Firmicutes,4I0CF@91061|Bacilli,1ZIWG@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF3941) - - - - - - - - - - - - DUF3941 k141_26518_1 1453501.JELR01000001_gene2643 2.83e-235 665.0 COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,1RNIY@1236|Gammaproteobacteria,4644H@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine sufS - 2.8.1.7,4.4.1.16 ko:K11717 ko00450,ko01100,map00450,map01100 - R03599,R11528 RC00961,RC01789,RC02313 ko00000,ko00001,ko01000 - - - Aminotran_5,SufE k141_346_1 1123309.AQYB01000006_gene1892 4.49e-27 110.0 COG0270@1|root,COG0270@2|Bacteria,1TS3G@1239|Firmicutes,4IPYS@91061|Bacilli 91061|Bacilli L C-5 cytosine-specific DNA methylase - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k141_346_4 1196324.A374_07316 2.72e-68 211.0 COG0629@1|root,COG0629@2|Bacteria,1V3WT@1239|Firmicutes,4HH8I@91061|Bacilli 91061|Bacilli L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k141_346_5 1444310.JANV01000162_gene1218 4.45e-76 230.0 2EEPZ@1|root,32S72@2|Bacteria,1VDBH@1239|Firmicutes,4IRWC@91061|Bacilli,1ZGK7@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_15726_2 218284.CCDN010000002_gene2747 8.71e-52 174.0 COG0860@1|root,COG5632@1|root,COG0860@2|Bacteria,COG5632@2|Bacteria,1UYW5@1239|Firmicutes,4HF0Y@91061|Bacilli,1ZGSJ@1386|Bacillus 91061|Bacilli M N-acetylmuramoyl-L-alanine amidase - - - - - - - - - - - - - k141_26519_1 1294265.JCM21738_310 1.84e-115 337.0 COG1868@1|root,COG1868@2|Bacteria,1TPTM@1239|Firmicutes,4HAAY@91061|Bacilli,1ZCI6@1386|Bacillus 91061|Bacilli N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation fliM GO:0005575,GO:0005623,GO:0005886,GO:0006935,GO:0008150,GO:0009288,GO:0009425,GO:0009605,GO:0016020,GO:0040011,GO:0042221,GO:0042330,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0050896,GO:0050918,GO:0071944 - ko:K02416 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02035 - - - FliM,FliMN_C k141_2663_1 42565.FP66_07195 1.65e-233 659.0 COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,1RNRX@1236|Gammaproteobacteria,1XHXZ@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) ppk - 2.7.4.1 ko:K00937 ko00190,ko03018,map00190,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - PP_kinase,PP_kinase_C,PP_kinase_N k141_27531_1 218284.CCDN010000001_gene1642 3.08e-95 280.0 COG0110@1|root,COG0110@2|Bacteria,1TQEX@1239|Firmicutes,4HAJ0@91061|Bacilli,1ZDPK@1386|Bacillus 91061|Bacilli S COG0110 Acetyltransferase (isoleucine patch superfamily) maa - 2.3.1.79 ko:K00661 - - - - ko00000,ko01000 - - - CM_2,Hexapep,Hexapep_2,Mac k141_25228_1 1453501.JELR01000001_gene3207 2.21e-27 108.0 COG1054@1|root,COG1054@2|Bacteria,1MUFV@1224|Proteobacteria,1RNNU@1236|Gammaproteobacteria,464T0@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the UPF0176 family yceA - - ko:K07146 - - - - ko00000 - - - Rhodanese,Rhodanese_C k141_12197_1 1295642.H839_06534 2.11e-52 174.0 COG3391@1|root,COG3391@2|Bacteria,1U5TM@1239|Firmicutes,4IFHK@91061|Bacilli,1WHE4@129337|Geobacillus 91061|Bacilli S amine dehydrogenase activity - - - - - - - - - - - - - k141_1403_1 1499680.CCFE01000033_gene3938 9.2e-80 249.0 COG0772@1|root,COG0772@2|Bacteria,1TPGH@1239|Firmicutes,4HAV4@91061|Bacilli,1ZBSB@1386|Bacillus 91061|Bacilli D Belongs to the SEDS family rodA - - ko:K05837 - - - - ko00000,ko03036 - - - FTSW_RODA_SPOVE k141_33513_1 1279017.AQYJ01000029_gene3430 2.65e-74 224.0 COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,1S3QE@1236|Gammaproteobacteria,4683Z@72275|Alteromonadaceae 1236|Gammaproteobacteria FG Scavenger mRNA decapping enzyme C-term binding - - - ko:K02503 - - - - ko00000,ko04147 - - - HIT k141_16903_1 1279017.AQYJ01000025_gene593 9.57e-35 130.0 COG3975@1|root,COG3975@2|Bacteria,1QX25@1224|Proteobacteria,1RWD8@1236|Gammaproteobacteria,466PD@72275|Alteromonadaceae 1236|Gammaproteobacteria S protease with the C-terminal PDZ domain - - - - - - - - - - - - - k141_24009_1 1117647.M5M_07535 2.85e-51 173.0 COG2971@1|root,COG2971@2|Bacteria,1R41I@1224|Proteobacteria,1RPMK@1236|Gammaproteobacteria,1J5VB@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria G BadF BadG BcrA BcrD - - 2.7.1.8 ko:K18676 ko00520,ko01100,map00520,map01100 - R01961 RC00002,RC00017 ko00000,ko00001,ko01000 - - - BcrAD_BadFG k141_347_1 218284.CCDN010000008_gene4213 3.07e-65 203.0 COG0073@1|root,COG0073@2|Bacteria,1V3R1@1239|Firmicutes,4HHBI@91061|Bacilli,1ZD7F@1386|Bacillus 91061|Bacilli J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily ytpR GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 - ko:K06878 - - - - ko00000 - - - DUF4479,tRNA_bind k141_26520_1 1042377.AFPJ01000009_gene331 1.41e-31 120.0 COG2211@1|root,COG2211@2|Bacteria,1MWE4@1224|Proteobacteria,1SZYW@1236|Gammaproteobacteria 1236|Gammaproteobacteria G PUCC protein - - - ko:K08226 - - - - ko00000,ko02000 2.A.1.41 - - PUCC k141_7405_1 218284.CCDN010000001_gene1269 3.6e-136 395.0 COG2252@1|root,COG2252@2|Bacteria,1TQC6@1239|Firmicutes,4HBDC@91061|Bacilli,1ZD8U@1386|Bacillus 91061|Bacilli S permease pbuO_1 - - ko:K06901 - - - - ko00000,ko02000 2.A.1.40 - - Xan_ur_permease k141_37054_1 1116375.VEJY3_16706 6.63e-49 164.0 COG2207@1|root,COG2207@2|Bacteria,1Q3UX@1224|Proteobacteria,1RS88@1236|Gammaproteobacteria,1XZK0@135623|Vibrionales 135623|Vibrionales K helix_turn_helix, arabinose operon control protein - - - ko:K04033 - - - - ko00000,ko03000 - - - HTH_18 k141_37054_3 674977.VMC_36230 0.0 946.0 COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,1RMTB@1236|Gammaproteobacteria,1XVGV@135623|Vibrionales 135623|Vibrionales O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions groL2 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 - - - Cpn60_TCP1 k141_37054_4 1219076.N646_3714 1.23e-56 176.0 COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,1S8YR@1236|Gammaproteobacteria,1XY59@135623|Vibrionales 135623|Vibrionales O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter groS2 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - ko:K04078 - - - - ko00000,ko03029,ko03110 - - - Cpn10 k141_37054_5 1116375.VEJY3_16676 1.19e-61 191.0 COG0607@1|root,COG0607@2|Bacteria,1RHVM@1224|Proteobacteria,1SD9C@1236|Gammaproteobacteria,1XXY0@135623|Vibrionales 135623|Vibrionales M COG0607 Rhodanese-related sulfurtransferase pspE - - ko:K03972 - - - - ko00000 - - - Rhodanese k141_37054_6 1116375.VEJY3_16656 4.28e-28 103.0 2EK1G@1|root,33DRY@2|Bacteria,1NH6C@1224|Proteobacteria,1SGMZ@1236|Gammaproteobacteria,1XYPN@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF3012) - - - - - - - - - - - - DUF3012 k141_37054_7 1116375.VEJY3_16651 1.02e-215 598.0 COG1304@1|root,COG1304@2|Bacteria,1N6KI@1224|Proteobacteria,1RP1W@1236|Gammaproteobacteria,1XW3Q@135623|Vibrionales 135623|Vibrionales C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) fni - 5.3.3.2 ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095,M00096,M00364,M00365,M00366,M00367 R01123 RC00455 ko00000,ko00001,ko00002,ko01000 - - - FMN_dh k141_37054_8 1348635.BBJY01000003_gene3891 6.32e-107 317.0 COG2755@1|root,COG2755@2|Bacteria,1QM85@1224|Proteobacteria,1T147@1236|Gammaproteobacteria 1236|Gammaproteobacteria E lipolytic protein G-D-S-L family - - - - - - - - - - - - - k141_37054_9 1116375.VEJY3_16646 3.72e-87 273.0 COG0025@1|root,COG1226@1|root,COG0025@2|Bacteria,COG1226@2|Bacteria,1QTUE@1224|Proteobacteria,1T1HJ@1236|Gammaproteobacteria,1XUJX@135623|Vibrionales 135623|Vibrionales P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family - - - - - - - - - - - - Na_H_Exchanger,TrkA_N k141_16904_1 1453501.JELR01000001_gene3104 2.43e-64 199.0 2C3KM@1|root,32UH0@2|Bacteria,1N3F2@1224|Proteobacteria,1S9U2@1236|Gammaproteobacteria,46B2R@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_16904_2 1453501.JELR01000001_gene3105 3.07e-44 152.0 COG2141@1|root,COG2141@2|Bacteria,1MVF0@1224|Proteobacteria,1RMCE@1236|Gammaproteobacteria,465D0@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases yhbW GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - - - - - - - - - - Bac_luciferase k141_28843_1 1276756.AUEX01000007_gene1418 1.11e-08 59.3 COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2VGZM@28216|Betaproteobacteria,4ABW2@80864|Comamonadaceae 28216|Betaproteobacteria P Belongs to the ABC transporter superfamily - - - ko:K10112 ko02010,map02010 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1 - - ABC_tran,TOBE,TOBE_2 k141_28843_2 1202532.FF52_05530 1.12e-76 243.0 COG1649@1|root,COG1649@2|Bacteria,4NI9V@976|Bacteroidetes,1IN9U@117743|Flavobacteriia,2NYPG@237|Flavobacterium 976|Bacteroidetes S Glycosyl hydrolase-like 10 - - - - - - - - - - - - GHL10 k141_34726_2 218284.CCDN010000001_gene1185 4.72e-41 135.0 2BM31@1|root,32FK5@2|Bacteria,1UAUV@1239|Firmicutes,4IM7Q@91061|Bacilli,1ZJF4@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - DUF3892 k141_34726_3 218284.CCDN010000001_gene1186 3.28e-10 58.5 COG0500@1|root,COG2226@2|Bacteria,1U9IT@1239|Firmicutes,4HDV5@91061|Bacilli,1ZC30@1386|Bacillus 91061|Bacilli Q Methionine biosynthesis protein MetW rebM - - - - - - - - - - - Methyltransf_11 k141_26521_1 1408303.JNJJ01000013_gene1667 3.08e-97 305.0 COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,4HAG1@91061|Bacilli,1ZARG@1386|Bacillus 91061|Bacilli J Belongs to the class-I aminoacyl-tRNA synthetase family leuS GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Anticodon_1,tRNA-synt_1,tRNA-synt_1_2 k141_4968_1 1294265.JCM21738_2375 1.66e-43 154.0 28HMX@1|root,2Z7WB@2|Bacteria,1TPJG@1239|Firmicutes,4HBRI@91061|Bacilli,1ZCDH@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_4968_2 1294265.JCM21738_2374 1.09e-97 288.0 COG1131@1|root,COG1131@2|Bacteria,1TQIH@1239|Firmicutes,4HCT1@91061|Bacilli,1ZCRH@1386|Bacillus 91061|Bacilli V ABC transporter CcmA5 - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_15727_2 218284.CCDN010000003_gene2975 1.96e-105 306.0 COG1658@1|root,COG1658@2|Bacteria,1V3K3@1239|Firmicutes,4HH5Y@91061|Bacilli,1ZFNN@1386|Bacillus 91061|Bacilli J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step rnmV GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043822,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 3.1.26.8 ko:K05985 - - - - ko00000,ko01000 - - - DUF4093,Toprim,Toprim_4 k141_348_1 218284.CCDN010000001_gene1391 6.85e-76 231.0 COG4814@1|root,COG4814@2|Bacteria,1V910@1239|Firmicutes,4HF90@91061|Bacilli,1ZHBI@1386|Bacillus 91061|Bacilli S Alpha/beta hydrolase of unknown function (DUF915) - - - - - - - - - - - - DUF915 k141_12199_1 1294265.JCM21738_4367 1.25e-223 649.0 COG1197@1|root,COG1197@2|Bacteria,1TPF1@1239|Firmicutes,4H9NB@91061|Bacilli,1ZBAK@1386|Bacillus 91061|Bacilli L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd - - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF k141_9752_1 218284.CCDN010000001_gene75 2.19e-139 396.0 COG1191@1|root,COG1191@2|Bacteria,1TPDD@1239|Firmicutes,4H9MN@91061|Bacilli,1ZB53@1386|Bacillus 91061|Bacilli K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released sigG - - ko:K03091 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r3,Sigma70_r4 k141_9752_2 218284.CCDN010000001_gene76 2.67e-161 452.0 COG1191@1|root,COG1191@2|Bacteria,1TP3T@1239|Firmicutes,4H9PG@91061|Bacilli,1ZBKD@1386|Bacillus 91061|Bacilli K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released sigE GO:0000003,GO:0000988,GO:0000990,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016020,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043254,GO:0043934,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - ko:K03091 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4 k141_34737_1 1499680.CCFE01000021_gene2221 1.27e-53 178.0 28I0M@1|root,2ZATW@2|Bacteria,1UZIU@1239|Firmicutes,4HCZK@91061|Bacilli,1ZC7Y@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3231) - - - - - - - - - - - - DUF3231 k141_10945_1 218284.CCDN010000001_gene1346 1.19e-133 389.0 COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,4HF1R@91061|Bacilli,1ZDU3@1386|Bacillus 91061|Bacilli M Belongs to the peptidase S11 family - - 3.4.16.4 ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - PBP5_C,Peptidase_S11 k141_18159_1 218284.CCDN010000001_gene67 5.17e-133 403.0 COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,4HAWB@91061|Bacilli,1ZAQK@1386|Bacillus 91061|Bacilli J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS - 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1,zf-FPG_IleRS k141_26555_3 876269.ARWA01000001_gene3394 6.46e-34 130.0 COG1157@1|root,COG1157@2|Bacteria,1MUH6@1224|Proteobacteria,2TRXU@28211|Alphaproteobacteria,3N9WV@45404|Beijerinckiaceae 28211|Alphaproteobacteria NU ATP synthase alpha/beta family, nucleotide-binding domain fliI GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0009288,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0042995,GO:0043226,GO:0043228,GO:0044464 3.6.3.14 ko:K02412 ko02040,map02040 - - - ko00000,ko00001,ko01000,ko02035,ko02044 3.A.6.2,3.A.6.3 - - ATP-synt_ab k141_16942_2 218284.CCDN010000002_gene2109 2.18e-162 469.0 COG1249@1|root,COG1249@2|Bacteria,1UYJP@1239|Firmicutes,4HCWF@91061|Bacilli,1ZED9@1386|Bacillus 91061|Bacilli C Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain - - 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyr_redox_2,Pyr_redox_dim k141_20403_1 406124.ACPC01000019_gene3132 2.9e-40 147.0 COG0013@1|root,COG0013@2|Bacteria,1TSBZ@1239|Firmicutes,4HADV@91061|Bacilli,1ZDMJ@1386|Bacillus 91061|Bacilli J metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain alaS_2 - 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DHHA1,tRNA-synt_2c,tRNA_SAD k141_15743_1 218284.CCDN010000008_gene4252 4.33e-106 315.0 COG0626@1|root,COG0626@2|Bacteria,1TPC7@1239|Firmicutes,4IS7E@91061|Bacilli,1ZS1S@1386|Bacillus 91061|Bacilli E methionine gamma-lyase megL - 4.4.1.11 ko:K01761 ko00270,ko00450,map00270,map00450 - R00654,R04770 RC00196,RC00348,RC01209,RC01210 ko00000,ko00001,ko01000 - - - Cys_Met_Meta_PP k141_13394_1 218284.CCDN010000001_gene1767 4.25e-122 350.0 COG1999@1|root,COG1999@2|Bacteria,1V03J@1239|Firmicutes,4HET3@91061|Bacilli,1ZFJQ@1386|Bacillus 91061|Bacilli S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems - - - ko:K07152 - - - - ko00000,ko03029 - - - SCO1-SenC k141_19267_1 1294265.JCM21738_3524 1.98e-121 355.0 COG4851@1|root,COG4851@2|Bacteria,1TSYE@1239|Firmicutes,4HBI8@91061|Bacilli,1ZBGV@1386|Bacillus 91061|Bacilli S COG4851 Protein involved in sex pheromone biosynthesis camS - - - - - - - - - - - CamS k141_28856_1 218284.CCDN010000001_gene524 1.18e-55 190.0 COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HB1B@91061|Bacilli,1ZC0T@1386|Bacillus 91061|Bacilli T Signal transduction histidine kinase phoR - 2.7.13.3 ko:K07636 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_9,sCache_like k141_28856_2 1399115.U719_12220 1.39e-21 90.1 COG0745@1|root,COG0745@2|Bacteria,1TPWS@1239|Firmicutes,4H9KP@91061|Bacilli 91061|Bacilli KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain phoP - - ko:K07658 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C k141_34738_1 1336208.JADY01000004_gene3471 3.68e-42 142.0 COG0509@1|root,COG0509@2|Bacteria,1RGV7@1224|Proteobacteria,2U9BY@28211|Alphaproteobacteria,2JSV1@204441|Rhodospirillales 204441|Rhodospirillales E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein gcvH - - ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 - - - GCV_H k141_34738_2 1122185.N792_05380 6.15e-06 48.1 COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,1RND3@1236|Gammaproteobacteria,1X35C@135614|Xanthomonadales 135614|Xanthomonadales E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor gcvP - 1.4.4.2 ko:K00281,ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko00002,ko01000 - - - GDC-P k141_12230_1 218284.CCDN010000001_gene78 5.88e-133 387.0 COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,4H9WZ@91061|Bacilli,1ZC2F@1386|Bacillus 91061|Bacilli D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity ftsZ GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030428,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03531 ko04112,map04112 - - - ko00000,ko00001,ko02048,ko03036,ko04812 - - - FtsZ_C,Tubulin k141_16943_2 344747.PM8797T_09004 4.68e-28 105.0 COG1695@1|root,COG1695@2|Bacteria,2J3HZ@203682|Planctomycetes 203682|Planctomycetes K Transcriptional regulator PadR-like family - - - - - - - - - - - - PadR k141_4996_1 218284.CCDN010000004_gene3063 1.26e-108 322.0 COG1597@1|root,COG1597@2|Bacteria,1TRGQ@1239|Firmicutes,4HDR5@91061|Bacilli,1ZCT6@1386|Bacillus 91061|Bacilli I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase bmrU - - - - - - - - - - - DAGK_cat k141_13395_1 218284.CCDN010000001_gene611 8.35e-90 280.0 COG2199@1|root,COG3706@2|Bacteria,1TQIK@1239|Firmicutes,4HEDD@91061|Bacilli,1ZB59@1386|Bacillus 91061|Bacilli T COG2199 FOG GGDEF domain - - - - - - - - - - - - GAF,GAF_2,GGDEF k141_25245_1 1536773.R70331_25170 1.39e-48 160.0 COG3340@1|root,COG3340@2|Bacteria,1UYTJ@1239|Firmicutes,4HFAT@91061|Bacilli,26W48@186822|Paenibacillaceae 91061|Bacilli E Belongs to the peptidase S51 family - - 3.4.13.21 ko:K05995 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S51 k141_22880_1 103690.17129981 1.76e-61 214.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1G0GP@1117|Cyanobacteria,1HIMK@1161|Nostocales 1117|Cyanobacteria G Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate ppsA - 2.7.9.2 ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 M00173,M00374 R00199 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - Intein_splicing,PEP-utilizers,PEP-utilizers_C,PPDK_N k141_18160_1 665959.HMPREF1013_05490 5.43e-65 202.0 COG1633@1|root,COG1633@2|Bacteria,1V9AF@1239|Firmicutes,4HIP7@91061|Bacilli,1ZGFE@1386|Bacillus 91061|Bacilli S Rubrerythrin yhjR - - - - - - - - - - - DUF2202,Ferritin_2,Rubrerythrin k141_27645_1 218284.CCDN010000005_gene3434 5e-229 639.0 COG0260@1|root,COG0260@2|Bacteria,1TPJZ@1239|Firmicutes,4HAPW@91061|Bacilli,1ZBZU@1386|Bacillus 91061|Bacilli E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides pepA - 3.4.11.1 ko:K01255 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - Peptidase_M17,Peptidase_M17_N k141_17072_1 218284.CCDN010000005_gene3174 1.26e-41 140.0 293PD@1|root,2ZR52@2|Bacteria,1V3PX@1239|Firmicutes,4HI32@91061|Bacilli,1ZFA0@1386|Bacillus 91061|Bacilli S Putative zincin peptidase yhaK - - - - - - - - - - - DUF3267 k141_19466_1 1279017.AQYJ01000022_gene2738 4.09e-17 76.6 COG3767@1|root,COG3767@2|Bacteria 2|Bacteria - - - - 3.2.1.4 ko:K01179 ko00500,ko01100,map00500,map01100 - R06200,R11307,R11308 - ko00000,ko00001,ko01000 - GH5,GH9 - EF-hand_5 k141_19466_2 1279017.AQYJ01000022_gene2737 4.44e-189 566.0 COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,1RMU1@1236|Gammaproteobacteria,464K7@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG1643 HrpA-like helicases hrpA GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0006139,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 3.6.4.13 ko:K03578 - - - - ko00000,ko01000 - - - DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind k141_34904_1 1294265.JCM21738_575 1.86e-192 547.0 COG0860@1|root,COG3103@1|root,COG0860@2|Bacteria,COG3103@2|Bacteria,COG4991@2|Bacteria,1UYPW@1239|Firmicutes,4HBVT@91061|Bacilli,1ZDI1@1386|Bacillus 91061|Bacilli M COG3103 SH3 domain protein lytH GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - Amidase_3,SH3_3 k141_5237_2 218284.CCDN010000007_gene3823 5.66e-68 207.0 COG3766@1|root,COG3766@2|Bacteria,1V3VY@1239|Firmicutes,4HI1T@91061|Bacilli,1ZQI9@1386|Bacillus 91061|Bacilli S Domain of Unknown Function (DUF350) - - - ko:K08989 - - - - ko00000 - - - DUF350 k141_20608_1 1294265.JCM21738_3287 1.91e-54 174.0 COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,4HIRK@91061|Bacilli,1ZGCW@1386|Bacillus 91061|Bacilli O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ grpE GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 - ko:K03687 - - - - ko00000,ko03029,ko03110 - - - GrpE k141_20608_2 1294265.JCM21738_3286 5.52e-144 412.0 COG1420@1|root,COG1420@2|Bacteria,1TQP7@1239|Firmicutes,4HAX5@91061|Bacilli,1ZBQV@1386|Bacillus 91061|Bacilli K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons hrcA GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K03705 - - - - ko00000,ko03000 - - - HrcA,HrcA_DNA-bdg k141_33785_1 1279017.AQYJ01000021_gene2907 2.05e-67 221.0 COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,1RNYW@1236|Gammaproteobacteria,46415@72275|Alteromonadaceae 1236|Gammaproteobacteria OU COG0616 Periplasmic serine proteases (ClpP class) sppA GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0010467,GO:0016020,GO:0016021,GO:0016485,GO:0016787,GO:0019538,GO:0031224,GO:0031226,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 - ko:K04773 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S49 k141_24177_1 218284.CCDN010000001_gene872 2.2e-50 161.0 2E9AA@1|root,2ZPC5@2|Bacteria,1W445@1239|Firmicutes,4I0GF@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - k141_24177_2 218284.CCDN010000001_gene871 4.09e-99 288.0 2ER1M@1|root,33IM5@2|Bacteria,1VQRC@1239|Firmicutes,4HSFK@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - HK97-gp10_like k141_24177_3 218284.CCDN010000001_gene870 1.06e-48 156.0 2FH90@1|root,3493C@2|Bacteria,1W17N@1239|Firmicutes,4HZ2J@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - k141_8826_2 218284.CCDN010000001_gene545 1.2e-48 159.0 COG4508@1|root,COG4508@2|Bacteria,1V6PI@1239|Firmicutes,4HJBB@91061|Bacilli,1ZGXN@1386|Bacillus 91061|Bacilli S dUTPase - - - - - - - - - - - - dUTPase_2 k141_4085_1 1116375.VEJY3_00755 2.22e-113 335.0 COG0457@1|root,COG0457@2|Bacteria,1MVCA@1224|Proteobacteria,1RS02@1236|Gammaproteobacteria,1XTJF@135623|Vibrionales 135623|Vibrionales S Tetratricopeptide repeat - - - - - - - - - - - - TPR_8 k141_7538_1 1294265.JCM21738_2707 5.3e-66 200.0 2CGTU@1|root,32RYH@2|Bacteria,1VCWD@1239|Firmicutes,4HMQV@91061|Bacilli,1ZHXS@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3055) - - - - - - - - - - - - DUF3055 k141_7538_2 1294265.JCM21738_2706 7.06e-20 82.8 2AN64@1|root,31D41@2|Bacteria,1V7Z3@1239|Firmicutes,4HJDV@91061|Bacilli,1ZFW5@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF1885) - - - - - - - - - - - - DUF1885 k141_28964_1 1279017.AQYJ01000029_gene3646 1.52e-79 256.0 COG1506@1|root,COG1506@2|Bacteria,1MUJ3@1224|Proteobacteria,1RRN4@1236|Gammaproteobacteria,465BC@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases pqqM - - - - - - - - - - - PD40,Peptidase_S9 k141_25466_2 1280001.BAOA01000026_gene5072 4.66e-115 330.0 COG0748@1|root,COG0748@2|Bacteria,1N0X1@1224|Proteobacteria,1S9AY@1236|Gammaproteobacteria,1XSSN@135623|Vibrionales 135623|Vibrionales P heme iron utilization protein hutZ - - ko:K07226 - - - - ko00000 - - - Putative_PNPOx k141_25466_3 223926.28808597 2.01e-193 539.0 COG0784@1|root,COG0835@1|root,COG0784@2|Bacteria,COG0835@2|Bacteria,1PQPU@1224|Proteobacteria,1RYEZ@1236|Gammaproteobacteria,1XTKV@135623|Vibrionales 135623|Vibrionales T COG0835 Chemotaxis signal transduction protein - - - ko:K03415 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - CheW,Response_reg k141_25466_4 674977.VMC_16090 1.71e-61 188.0 COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,1S9DN@1236|Gammaproteobacteria,1XXXZ@135623|Vibrionales 135623|Vibrionales G COG0760 Parvulin-like peptidyl-prolyl isomerase ppiC - 5.2.1.8 ko:K03769 - - - - ko00000,ko01000,ko03110 - - - Rotamase_3 k141_25466_5 1517681.HW45_26145 7.26e-148 424.0 COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,1RMIR@1236|Gammaproteobacteria,1XTK9@135623|Vibrionales 135623|Vibrionales M COG0739 Membrane proteins related to metalloendopeptidases tagE - - - - - - - - - - - Peptidase_M23 k141_12535_2 561229.Dd1591_1049 5.12e-59 207.0 COG3408@1|root,COG3408@2|Bacteria,1NJCP@1224|Proteobacteria,1RXM5@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Bacterial alpha-L-rhamnosidase C-terminal domain - - 3.2.1.40 ko:K05989 - - - - ko00000,ko01000 - - - Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N k141_21861_1 218284.CCDN010000002_gene2133 6.12e-92 271.0 COG1670@1|root,COG1670@2|Bacteria,1V2C6@1239|Firmicutes,4HG3C@91061|Bacilli,1ZFP6@1386|Bacillus 91061|Bacilli J Acetyltransferase (GNAT) domain yoaA - 2.3.1.128 ko:K03790 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 k141_19489_1 1116375.VEJY3_23831 1.33e-206 573.0 COG4605@1|root,COG4605@2|Bacteria,1NM9D@1224|Proteobacteria,1RPAH@1236|Gammaproteobacteria,1Y2BV@135623|Vibrionales 135623|Vibrionales P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily - - - ko:K02015 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - FecCD k141_19489_2 1116375.VEJY3_23836 3.37e-152 429.0 COG4604@1|root,COG4604@2|Bacteria,1QU78@1224|Proteobacteria,1RP3Y@1236|Gammaproteobacteria,1XVHH@135623|Vibrionales 135623|Vibrionales P abc transporter atp-binding protein - - 3.6.3.34 ko:K02013 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 - - ABC_tran k141_20623_1 1279017.AQYJ01000022_gene2628 5.15e-282 794.0 COG4656@1|root,COG4656@2|Bacteria,1QTUI@1224|Proteobacteria,1RMIM@1236|Gammaproteobacteria,4655V@72275|Alteromonadaceae 1236|Gammaproteobacteria C Part of a membrane complex involved in electron transport rnfC GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0055114 - ko:K03615 - - - - ko00000 - - - Complex1_51K,Fer4_10,Fer4_7,Fer4_8,RnfC_N,SLBB k141_20623_3 1279017.AQYJ01000022_gene2630 3.86e-119 342.0 COG4657@1|root,COG4657@2|Bacteria,1MU8X@1224|Proteobacteria,1RQDN@1236|Gammaproteobacteria,464YB@72275|Alteromonadaceae 1236|Gammaproteobacteria C Part of a membrane complex involved in electron transport rnfA - - ko:K03617 - - - - ko00000 - - - Rnf-Nqr k141_36030_1 1294265.JCM21738_4303 1.01e-112 334.0 COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,4H9WZ@91061|Bacilli,1ZDE2@1386|Bacillus 91061|Bacilli D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity ftsZ GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03531 ko04112,map04112 - - - ko00000,ko00001,ko02048,ko03036,ko04812 - - - FtsZ_C,Tubulin k141_1598_1 1453501.JELR01000001_gene1930 8.54e-47 160.0 COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,1RPGJ@1236|Gammaproteobacteria,4651N@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0436 Aspartate tyrosine aromatic aminotransferase dapC - 2.6.1.17 ko:K14261,ko:K14267 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R04475 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k141_1598_2 1453501.JELR01000001_gene1931 1.12e-43 157.0 COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,1RN5T@1236|Gammaproteobacteria,464WE@72275|Alteromonadaceae 1236|Gammaproteobacteria O Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen glnD GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008773,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019538,GO:0019752,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0070569,GO:0071704,GO:0140096,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.59 ko:K00990 ko02020,map02020 - - - ko00000,ko00001,ko01000 - - - ACT,GlnD_UR_UTase,HD,NTP_transf_2 k141_10036_1 333138.LQ50_19810 3.39e-53 172.0 2CDA7@1|root,333AV@2|Bacteria,1VHFF@1239|Firmicutes,4HRPJ@91061|Bacilli,1ZHIE@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_13680_1 1122915.AUGY01000014_gene2735 2.45e-33 130.0 COG1376@1|root,COG1376@2|Bacteria,1U2DJ@1239|Firmicutes,4IBZC@91061|Bacilli,271R4@186822|Paenibacillaceae 91061|Bacilli S L,D-transpeptidase catalytic domain - - - - - - - - - - - - YkuD k141_612_1 1042377.AFPJ01000015_gene1612 4.73e-99 312.0 COG1199@1|root,COG1199@2|Bacteria,1MVRJ@1224|Proteobacteria,1RQ7B@1236|Gammaproteobacteria,464G6@72275|Alteromonadaceae 1236|Gammaproteobacteria KL COG1199 Rad3-related DNA helicases - - 3.6.4.12 ko:K10844 ko03022,ko03420,map03022,map03420 M00290 - - ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - DEAD_2,Helicase_C_2 k141_34932_2 218284.CCDN010000001_gene93 1.3e-97 284.0 COG2001@1|root,COG2001@2|Bacteria,1V3JD@1239|Firmicutes,4HH23@91061|Bacilli,1ZFN0@1386|Bacillus 91061|Bacilli K Belongs to the MraZ family mraZ GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - ko:K03925 - - - - ko00000 - - - MraZ k141_34932_3 1298598.JCM21714_704 1.07e-17 84.7 COG4365@1|root,COG4365@2|Bacteria,1TQ2P@1239|Firmicutes,4HA2Z@91061|Bacilli,470CG@74385|Gracilibacillus 91061|Bacilli S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH bshC - - ko:K22136 - - - - ko00000 - - - BshC k141_8846_1 1279017.AQYJ01000026_gene58 6.47e-197 619.0 COG1361@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4932@2|Bacteria,1R5G4@1224|Proteobacteria,1SEWA@1236|Gammaproteobacteria,469S7@72275|Alteromonadaceae 1236|Gammaproteobacteria M Domain of unknown function DUF11 - - - - - - - - - - - - DUF11,SdrD_B k141_20624_1 1550091.JROE01000001_gene4059 6.72e-28 111.0 COG1117@1|root,COG1117@2|Bacteria,4NFAB@976|Bacteroidetes,1IVED@117747|Sphingobacteriia 976|Bacteroidetes P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system - - 3.6.3.27 ko:K02036 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 - - ABC_tran k141_11211_1 1379270.AUXF01000003_gene3543 3.38e-51 173.0 COG1013@1|root,COG1013@2|Bacteria,1ZSWT@142182|Gemmatimonadetes 142182|Gemmatimonadetes C Thiamine pyrophosphate enzyme, C-terminal TPP binding domain - - 1.2.7.11,1.2.7.3 ko:K00175 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C k141_613_2 1347086.CCBA010000004_gene4405 6.41e-32 127.0 COG1404@1|root,COG1404@2|Bacteria,1TQRU@1239|Firmicutes,4HAZA@91061|Bacilli,1ZAZK@1386|Bacillus 91061|Bacilli O Belongs to the peptidase S8 family - - - - - - - - - - - - Inhibitor_I9,PA,PPC,Peptidase_S8,SLH k141_32428_1 1042377.AFPJ01000013_gene1733 2.93e-109 318.0 COG0225@1|root,COG0225@2|Bacteria,1MVUS@1224|Proteobacteria,1RNWU@1236|Gammaproteobacteria,466E8@72275|Alteromonadaceae 1236|Gammaproteobacteria O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine msrA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006807,GO:0006950,GO:0006979,GO:0008113,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016667,GO:0016671,GO:0019538,GO:0030091,GO:0033744,GO:0036456,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0055114,GO:0071704,GO:1901564 1.8.4.11 ko:K07304 - - - - ko00000,ko01000 - - iECSE_1348.ECSE_4525 PMSR k141_32428_3 1453501.JELR01000001_gene2160 1.01e-183 525.0 COG3203@1|root,COG3203@2|Bacteria 2|Bacteria M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - - - - - - - - - - Porin_4 k141_32428_4 1453501.JELR01000001_gene2159 5.26e-62 196.0 COG2214@1|root,COG2214@2|Bacteria,1PUS9@1224|Proteobacteria,1SER6@1236|Gammaproteobacteria,468NM@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG2214 DnaJ-class molecular chaperone - - - - - - - - - - - - DnaJ k141_32428_5 1279017.AQYJ01000025_gene684 9.54e-129 372.0 COG2227@1|root,COG2227@2|Bacteria,1MY0S@1224|Proteobacteria,1RP69@1236|Gammaproteobacteria,466U7@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs cmoM GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097697,GO:0140098,GO:0140101,GO:1901360 - ko:K06219 - - - - ko00000 - - - Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31 k141_32428_6 604354.TSIB_1782 9.31e-17 80.5 COG1694@1|root,COG2606@1|root,arCOG01084@2157|Archaea,arCOG04332@2157|Archaea,2XZ89@28890|Euryarchaeota,244GY@183968|Thermococci 183968|Thermococci S MazG-like family - - - - - - - - - - - - MazG-like,tRNA_edit k141_32428_7 1453501.JELR01000001_gene2157 1.57e-113 332.0 COG3821@1|root,COG3821@2|Bacteria,1RDXR@1224|Proteobacteria,1S43M@1236|Gammaproteobacteria,466W1@72275|Alteromonadaceae 1236|Gammaproteobacteria S membrane - - - - - - - - - - - - DUF599 k141_32428_8 1279017.AQYJ01000025_gene687 0.0 1417.0 COG1026@1|root,COG1026@2|Bacteria,1MVDJ@1224|Proteobacteria,1RYNI@1236|Gammaproteobacteria,465V1@72275|Alteromonadaceae 1236|Gammaproteobacteria S Zn-dependent peptidases, insulinase-like - - - ko:K06972 - - - - ko00000,ko01000,ko01002 - - - M16C_assoc,Peptidase_M16,Peptidase_M16_C k141_12536_1 218284.CCDN010000011_gene4404 7.96e-317 867.0 COG3666@1|root,COG3666@2|Bacteria,1TQQ9@1239|Firmicutes,4H9KK@91061|Bacilli,1ZCCI@1386|Bacillus 91061|Bacilli L Transposase domain (DUF772) - - - - - - - - - - - - DDE_Tnp_1,DDE_Tnp_1_6,DUF772 k141_11212_1 218284.CCDN010000004_gene3135 3.3e-75 226.0 29UM7@1|root,30FYQ@2|Bacteria,1UA1E@1239|Firmicutes,4IKA5@91061|Bacilli,1ZG42@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_27662_1 204669.Acid345_2812 8.32e-109 329.0 COG0364@1|root,COG0364@2|Bacteria,3Y2JZ@57723|Acidobacteria,2JHKE@204432|Acidobacteriia 204432|Acidobacteriia G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone - - 1.1.1.363,1.1.1.49 ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 M00004,M00006,M00008 R00835,R02736,R10907 RC00001,RC00066 ko00000,ko00001,ko00002,ko01000,ko04147 - - - G6PD_C,G6PD_N k141_36031_2 545693.BMQ_4026 4.99e-17 73.2 2EKRV@1|root,33EFM@2|Bacteria,1VQ20@1239|Firmicutes,4HSEI@91061|Bacilli,1ZK5P@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_6474_1 218284.CCDN010000006_gene3512 1.07e-162 470.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HB0J@91061|Bacilli,1ZBUU@1386|Bacillus 91061|Bacilli I acyl-CoA dehydrogenase fadE - 1.3.8.1 ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 - R01175,R01178,R02661,R03172,R04751 RC00052,RC00068,RC00076,RC00120,RC00148 ko00000,ko00001,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_17084_1 1453501.JELR01000005_gene1700 1.79e-186 534.0 COG0596@1|root,COG0596@2|Bacteria,1R6KU@1224|Proteobacteria,1RNTQ@1236|Gammaproteobacteria,467P9@72275|Alteromonadaceae 1236|Gammaproteobacteria S TAP-like protein - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_4 k141_17084_2 1042377.AFPJ01000004_gene411 3.01e-85 257.0 COG4555@1|root,COG4555@2|Bacteria,1QU2T@1224|Proteobacteria,1RY2V@1236|Gammaproteobacteria,46CK1@72275|Alteromonadaceae 1236|Gammaproteobacteria CP ATPases associated with a variety of cellular activities natA - 3.6.3.7 ko:K09697 ko02010,ko02020,map02010,map02020 M00253 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.115 - - ABC_tran k141_18372_1 1279017.AQYJ01000025_gene722 4.45e-41 138.0 COG2050@1|root,COG2050@2|Bacteria,1N5HF@1224|Proteobacteria,1RNAK@1236|Gammaproteobacteria,46DIT@72275|Alteromonadaceae 1236|Gammaproteobacteria Q protein, possibly involved in aromatic compounds catabolism yigI GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - - - - - - - - - - 4HBT k141_18372_2 1279017.AQYJ01000025_gene723 8.56e-306 837.0 COG1249@1|root,COG1249@2|Bacteria,1MVVE@1224|Proteobacteria,1RMJT@1236|Gammaproteobacteria,465C1@72275|Alteromonadaceae 1236|Gammaproteobacteria C Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation sthA GO:0000166,GO:0003674,GO:0003824,GO:0003957,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0008746,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0016491,GO:0016651,GO:0016652,GO:0019725,GO:0022857,GO:0022890,GO:0034220,GO:0036094,GO:0042592,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050662,GO:0050789,GO:0050794,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0065007,GO:0065008,GO:0097159,GO:0098655,GO:0098660,GO:0098662,GO:1901265,GO:1901363,GO:1902600 1.6.1.1 ko:K00322 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - iECED1_1282.ECED1_4669,iECs_1301.ECs4891,iZ_1308.Z5521 Pyr_redox_2,Pyr_redox_dim k141_18372_3 1453501.JELR01000001_gene2467 2.38e-32 114.0 COG2991@1|root,COG2991@2|Bacteria,1N8TF@1224|Proteobacteria,1SCB5@1236|Gammaproteobacteria,468F5@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria - - - ko:K05952 - - - - ko00000 - - - NqrM k141_18372_4 1279017.AQYJ01000025_gene725 1.86e-149 428.0 COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,1RNMZ@1236|Gammaproteobacteria,46547@72275|Alteromonadaceae 1236|Gammaproteobacteria H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein apbE GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016740,GO:0017013,GO:0019538,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0031975,GO:0036094,GO:0036211,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0071944,GO:0071949,GO:0097159,GO:0098552,GO:0098567,GO:1901265,GO:1901363,GO:1901564 2.7.1.180 ko:K03734 - - - - ko00000,ko01000 - - - ApbE k141_18372_5 1042377.AFPJ01000007_gene1899 1.54e-290 793.0 COG2871@1|root,COG2871@2|Bacteria,1QTUV@1224|Proteobacteria,1RPG5@1236|Gammaproteobacteria,4648D@72275|Alteromonadaceae 1236|Gammaproteobacteria C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway nqrF GO:0000166,GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030001,GO:0030964,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0044425,GO:0048037,GO:0050136,GO:0050660,GO:0050662,GO:0051179,GO:0051234,GO:0051536,GO:0051537,GO:0051540,GO:0055114,GO:0071949,GO:0097159,GO:0098796,GO:1901265,GO:1901363,GO:1902494 1.6.5.8 ko:K00351 - - - - ko00000,ko01000 - - - FAD_binding_6,Fer2,NAD_binding_1 k141_18372_6 1279017.AQYJ01000025_gene727 2.81e-131 374.0 COG2209@1|root,COG2209@2|Bacteria,1R33S@1224|Proteobacteria,1RMWV@1236|Gammaproteobacteria,464ST@72275|Alteromonadaceae 1236|Gammaproteobacteria C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol nqrE GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030001,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0051179,GO:0051234,GO:0055114,GO:0098796,GO:1902494 1.6.5.8 ko:K00350 - - - - ko00000,ko01000 - - - Rnf-Nqr k141_18372_7 1042377.AFPJ01000007_gene1901 8.95e-130 371.0 COG1347@1|root,COG1347@2|Bacteria,1MUZR@1224|Proteobacteria,1RNFE@1236|Gammaproteobacteria,46413@72275|Alteromonadaceae 1236|Gammaproteobacteria C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol nqrD GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015672,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030001,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0051179,GO:0051234,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.6.5.8 ko:K00349 - - - - ko00000,ko01000 - - - Rnf-Nqr k141_18372_8 1453501.JELR01000001_gene2472 3.95e-146 416.0 COG2869@1|root,COG2869@2|Bacteria,1MVDI@1224|Proteobacteria,1RR85@1236|Gammaproteobacteria,464V9@72275|Alteromonadaceae 1236|Gammaproteobacteria C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol nqrC - 1.6.5.8 ko:K00348 - - - - ko00000,ko01000 - - - FMN_bind k141_5252_1 218284.CCDN010000002_gene2829 2.38e-84 253.0 COG0778@1|root,COG0778@2|Bacteria,1V1PI@1239|Firmicutes,4HB7V@91061|Bacilli,1ZBI6@1386|Bacillus 91061|Bacilli C nitroreductase frp - - - - - - - - - - iYO844.BSU07830 Nitroreductase k141_30080_2 1198114.AciX9_0718 2.91e-18 85.5 COG5516@1|root,COG5516@2|Bacteria,3Y5TP@57723|Acidobacteria,2JMXX@204432|Acidobacteriia 204432|Acidobacteriia S CGNR zinc finger - - - - - - - - - - - - ABATE,zf-CGNR k141_14664_1 223926.28805438 1.4e-261 724.0 COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,1RMD6@1236|Gammaproteobacteria,1XUJ7@135623|Vibrionales 135623|Vibrionales M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan murE GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 ko:K01928 ko00300,ko00550,map00300,map00550 - R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M k141_14664_2 1116375.VEJY3_02050 0.0 1077.0 COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,1RNGW@1236|Gammaproteobacteria,1XTH5@135623|Vibrionales 135623|Vibrionales D Catalyzes cross-linking of the peptidoglycan cell wall at the division septum ftsI - 3.4.16.4 ko:K03587 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011,ko03036 - - - PBP_dimer,Transpeptidase k141_14664_3 674977.VMC_28820 3.77e-62 191.0 COG3116@1|root,COG3116@2|Bacteria,1N9MH@1224|Proteobacteria,1SC7P@1236|Gammaproteobacteria,1XXXH@135623|Vibrionales 135623|Vibrionales D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic ftsL - - ko:K03586 - - - - ko00000,ko03036 - - - FtsL k141_14664_4 223926.28805435 2.97e-217 600.0 COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,1RM7M@1236|Gammaproteobacteria,1XU1Z@135623|Vibrionales 135623|Vibrionales J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA rsmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 ko:K03438 - - - - ko00000,ko01000,ko03009 - - - Methyltransf_5 k141_14664_5 672.VV93_v1c05480 6.94e-48 156.0 2E9J1@1|root,333RY@2|Bacteria,1NCU6@1224|Proteobacteria,1SF5Y@1236|Gammaproteobacteria,1XZ6K@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_14664_6 1116375.VEJY3_02030 6.42e-202 559.0 COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,1RM7U@1236|Gammaproteobacteria,1XU78@135623|Vibrionales 135623|Vibrionales H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA rsmI GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 2.1.1.198 ko:K07056 - - - - ko00000,ko01000,ko03009 - - - TP_methylase k141_14664_7 1116375.VEJY3_02025 0.0 1025.0 COG3107@1|root,COG3107@2|Bacteria,1MUHR@1224|Proteobacteria,1RXX4@1236|Gammaproteobacteria,1XT66@135623|Vibrionales 135623|Vibrionales M Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) lpoA - - ko:K07121 - - - - ko00000 - - - LppC k141_14664_8 1116375.VEJY3_02020 1.42e-74 224.0 COG0792@1|root,COG0792@2|Bacteria,1N6VN@1224|Proteobacteria,1SC8A@1236|Gammaproteobacteria,1XXQT@135623|Vibrionales 135623|Vibrionales L Uncharacterised protein family UPF0102 - - - ko:K07460 - - - - ko00000 - - - UPF0102 k141_14664_9 223926.28805430 4.56e-134 380.0 COG0279@1|root,COG0279@2|Bacteria,1NJ8X@1224|Proteobacteria,1RS1Y@1236|Gammaproteobacteria,1XUEU@135623|Vibrionales 135623|Vibrionales G Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate diaA - - ko:K12961 - - - - ko00000,ko03036 - - - SIS_2 k141_14664_10 223926.28805429 2.45e-104 306.0 COG2823@1|root,COG2823@2|Bacteria,1MUZ2@1224|Proteobacteria,1RY2B@1236|Gammaproteobacteria,1XVEM@135623|Vibrionales 135623|Vibrionales S periplasmic or secreted lipoprotein - - - - - - - - - - - - BON k141_14664_11 1116375.VEJY3_02005 8.23e-97 283.0 COG2969@1|root,COG2969@2|Bacteria,1MZ2Q@1224|Proteobacteria,1S8WT@1236|Gammaproteobacteria,1XWV9@135623|Vibrionales 135623|Vibrionales S stringent starvation protein b sspB - - ko:K03600 - - - - ko00000,ko03021 - - - SspB k141_14664_12 223926.28805427 1.29e-145 410.0 COG0625@1|root,COG0625@2|Bacteria,1MXJD@1224|Proteobacteria,1RP12@1236|Gammaproteobacteria,1XTQ9@135623|Vibrionales 135623|Vibrionales O stringent starvation protein A sspA - - ko:K03599 - - - - ko00000,ko02000,ko03021 1.A.12.3.1 - - GST_C,GST_N,GST_N_3 k141_14664_13 1116375.VEJY3_01995 4.16e-177 493.0 COG2857@1|root,COG2857@2|Bacteria,1QFU2@1224|Proteobacteria,1RN4Y@1236|Gammaproteobacteria,1XSUK@135623|Vibrionales 135623|Vibrionales P cytochrome c1 petC - - ko:K00413 ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152 - - ko00000,ko00001,ko00002 - - - Cytochrom_C1 k141_14664_14 223926.28805425 9.63e-308 838.0 COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,1RNCP@1236|Gammaproteobacteria,1XT8D@135623|Vibrionales 135623|Vibrionales C Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis petB - - ko:K00412 ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152 - - ko00000,ko00001,ko00002,ko03029 - - - Cytochrom_B_C,Cytochrome_B k141_14664_15 1280001.BAOA01000021_gene896 1.93e-135 384.0 COG0723@1|root,COG0723@2|Bacteria,1RAA2@1224|Proteobacteria,1RP9H@1236|Gammaproteobacteria,1XV6W@135623|Vibrionales 135623|Vibrionales C Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis petA - 1.10.2.2 ko:K00411 ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152 - - ko00000,ko00001,ko00002,ko01000 - - - Rieske,UCR_Fe-S_N k141_14664_16 1280001.BAOA01000021_gene895 1.09e-84 250.0 COG0103@1|root,COG0103@2|Bacteria,1RD4A@1224|Proteobacteria,1S3Q7@1236|Gammaproteobacteria,1XWX8@135623|Vibrionales 135623|Vibrionales J Belongs to the universal ribosomal protein uS9 family rpsI GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02996 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S9 k141_14664_17 674977.VMC_28960 3.03e-99 288.0 COG0102@1|root,COG0102@2|Bacteria,1RA11@1224|Proteobacteria,1S280@1236|Gammaproteobacteria,1XSDR@135623|Vibrionales 135623|Vibrionales J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly rplM GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02871 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L13 k141_14664_18 1116375.VEJY3_01970 2.65e-248 683.0 COG1485@1|root,COG1485@2|Bacteria,1MUUW@1224|Proteobacteria,1RMTJ@1236|Gammaproteobacteria,1XV3N@135623|Vibrionales 135623|Vibrionales D Reduces the stability of FtsZ polymers in the presence of ATP zapE - - ko:K06916 - - - - ko00000,ko03036 - - - AFG1_ATPase k141_14664_19 1116375.VEJY3_01965 2.43e-87 258.0 COG3105@1|root,COG3105@2|Bacteria,1N25P@1224|Proteobacteria,1S7WW@1236|Gammaproteobacteria,1XXEQ@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria yhcB - - ko:K09908 - - - - ko00000 - - - DUF1043 k141_14664_20 1116375.VEJY3_01960 7.36e-121 356.0 COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,1XSK2@135623|Vibrionales 135623|Vibrionales M Belongs to the peptidase S1C family degQ - 3.4.21.107 ko:K04771,ko:K04772 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ,PDZ_2,Trypsin_2 k141_34935_1 218284.CCDN010000001_gene137 6.33e-120 353.0 COG1875@1|root,COG1875@2|Bacteria,1UHTD@1239|Firmicutes,4HA4V@91061|Bacilli,1ZDIF@1386|Bacillus 91061|Bacilli T ATPase related to phosphate starvation-inducible protein PhoH ylaK - - ko:K07175 - - - - ko00000 - - - PIN_4,PhoH k141_15888_1 218284.CCDN010000001_gene667 7.13e-158 462.0 COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,4HBX7@91061|Bacilli,1ZBN6@1386|Bacillus 91061|Bacilli KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance relA GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5 ko:K00951 ko00230,map00230 - R00429 RC00002,RC00078 ko00000,ko00001,ko01000 - - iYO844.BSU27600 ACT_4,HD_4,RelA_SpoT,TGS k141_33798_1 1042377.AFPJ01000028_gene2170 4.64e-73 231.0 COG2197@1|root,COG2197@2|Bacteria 2|Bacteria K response regulator - - - - - - - - - - - - GerE,PAS_3 k141_33798_3 1279017.AQYJ01000028_gene2086 2.8e-56 185.0 COG2831@1|root,COG2831@2|Bacteria,1QW38@1224|Proteobacteria,1T2R4@1236|Gammaproteobacteria,464F6@72275|Alteromonadaceae 1236|Gammaproteobacteria U Protein of unknown function (DUF3570) - - - - - - - - - - - - DUF3570 k141_1601_1 401053.AciPR4_0872 1.06e-67 215.0 COG1077@1|root,COG1077@2|Bacteria,3Y3VC@57723|Acidobacteria,2JHQ2@204432|Acidobacteriia 204432|Acidobacteriia D cell shape determining protein MreB - - - ko:K03569 - - - - ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 - - MreB_Mbl k141_2945_2 1453501.JELR01000002_gene692 7.22e-26 100.0 COG0517@1|root,COG0517@2|Bacteria,1RJTX@1224|Proteobacteria,1S6K2@1236|Gammaproteobacteria,467TZ@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0517 FOG CBS domain - - - - - - - - - - - - CBS k141_9045_1 218284.CCDN010000002_gene2168 3.2e-107 325.0 COG1164@1|root,COG1164@2|Bacteria,1TQ5W@1239|Firmicutes,4HAN9@91061|Bacilli,1ZCRR@1386|Bacillus 91061|Bacilli E COG1164 Oligoendopeptidase F pepF2 - - - - - - - - - - - Peptidase_M3,Peptidase_M3_N k141_29129_2 218284.CCDN010000001_gene1517 2.75e-79 239.0 COG3584@1|root,COG3584@2|Bacteria,1V2K0@1239|Firmicutes,4HGVC@91061|Bacilli 91061|Bacilli M 3D domain - - - - - - - - - - - - 3D,LysM k141_33971_1 314265.R2601_27076 1.16e-23 100.0 COG1463@1|root,COG3008@1|root,COG1463@2|Bacteria,COG3008@2|Bacteria,1MU1T@1224|Proteobacteria,2TSTX@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q Paraquat-inducible protein B pqiB - - ko:K06192 - - - - ko00000 - - - MlaD k141_33971_2 314265.R2601_27071 1.12e-32 119.0 COG3009@1|root,COG3009@2|Bacteria,1RH03@1224|Proteobacteria,2U9EI@28211|Alphaproteobacteria 28211|Alphaproteobacteria S ABC-type transport auxiliary lipoprotein component - - - ko:K09857 - - - - ko00000 - - - ABC_trans_aux k141_6631_1 926562.Oweho_2054 4.12e-39 142.0 COG0668@1|root,COG0668@2|Bacteria,4PKII@976|Bacteroidetes,1IJA3@117743|Flavobacteriia 976|Bacteroidetes M mechanosensitive ion channel - - - ko:K03442 - - - - ko00000,ko02000 1.A.23.2 - - MS_channel,TM_helix k141_6631_2 1296990.H845_3513 0.000545 44.3 COG1285@1|root,COG1285@2|Bacteria,1RKY0@1224|Proteobacteria,2VGBG@28211|Alphaproteobacteria 28211|Alphaproteobacteria S MgtC family mgtC - - ko:K07507 - - - - ko00000,ko02000 9.B.20 - - MgtC k141_20779_1 1294265.JCM21738_2758 2.04e-157 446.0 COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,4HGRC@91061|Bacilli,1ZC6X@1386|Bacillus 91061|Bacilli O HflC and HflK could regulate a protease hflC - - ko:K04087 - M00742 - - ko00000,ko00002,ko01000 - - - Band_7 k141_790_1 1454004.AW11_00535 1.62e-138 410.0 COG2267@1|root,COG2267@2|Bacteria,1QTZP@1224|Proteobacteria,2VKTF@28216|Betaproteobacteria 28216|Betaproteobacteria I Serine aminopeptidase, S33 - - - - - - - - - - - - Abhydrolase_6,Hydrolase_4 k141_27828_1 1453501.JELR01000001_gene2142 2.11e-102 311.0 COG1115@1|root,COG1115@2|Bacteria,1MUI3@1224|Proteobacteria,1RMNF@1236|Gammaproteobacteria,464HE@72275|Alteromonadaceae 1236|Gammaproteobacteria E alanine symporter yaaJ GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03310 - - - - ko00000 2.A.25 - iEcE24377_1341.EcE24377A_0007 Na_Ala_symp k141_24439_1 1042377.AFPJ01000027_gene2670 4.29e-15 76.3 COG3325@1|root,COG3979@1|root,COG3325@2|Bacteria,COG3979@2|Bacteria,1MWAR@1224|Proteobacteria,1RPNS@1236|Gammaproteobacteria,4672D@72275|Alteromonadaceae 1236|Gammaproteobacteria G Glyco_18 chiA - 3.2.1.14 ko:K01183 ko00520,ko01100,map00520,map01100 - R01206,R02334 RC00467 ko00000,ko00001,ko01000 - GH18 - CBM_5_12,ChitinaseA_N,Glyco_hydro_18,REJ k141_24439_2 1453501.JELR01000002_gene103 3.22e-31 121.0 COG3469@1|root,COG3979@1|root,COG3469@2|Bacteria,COG3979@2|Bacteria,1MUUS@1224|Proteobacteria,1RYTJ@1236|Gammaproteobacteria,46AI1@72275|Alteromonadaceae 1236|Gammaproteobacteria G Carbohydrate binding domain chiA - 3.2.1.14 ko:K01183 ko00520,ko01100,map00520,map01100 - R01206,R02334 RC00467 ko00000,ko00001,ko01000 - GH18 - CBM_5_12,Glyco_hydro_18 k141_32623_2 666686.B1NLA3E_00620 2.36e-65 200.0 COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,4HIGF@91061|Bacilli,1ZG7C@1386|Bacillus 91061|Bacilli J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance rplR GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - ko:K02881 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L18p k141_18615_1 1116375.VEJY3_04085 0.0 1357.0 COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,1RPAG@1236|Gammaproteobacteria,1XSKY@135623|Vibrionales 135623|Vibrionales Q COG1020 Non-ribosomal peptide synthetase modules and related proteins - - 6.3.2.14 ko:K02364 ko01053,ko01110,ko01130,map01053,map01110,map01130 - R07644 RC00162,RC03046 ko00000,ko00001,ko01000,ko01008 - - - AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase k141_23351_1 768066.HELO_2982 2.45e-50 167.0 COG0662@1|root,COG1396@1|root,COG0662@2|Bacteria,COG1396@2|Bacteria,1RCYA@1224|Proteobacteria,1S4B9@1236|Gammaproteobacteria,1XJVH@135619|Oceanospirillales 135619|Oceanospirillales K XRE family transcriptional regulator - - - - - - - - - - - - Cupin_2,HTH_3 k141_23351_2 1279017.AQYJ01000029_gene3444 0.0 1241.0 COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,1RMZ8@1236|Gammaproteobacteria,4644P@72275|Alteromonadaceae 1236|Gammaproteobacteria I Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate fadB - 1.1.1.35,4.2.1.17,5.1.2.3,5.3.3.8 ko:K01782,ko:K01825 ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212 M00032,M00087 R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R04756,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094 RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01078,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 - - - 3HCDH,3HCDH_N,ECH_1 k141_23351_3 1042377.AFPJ01000036_gene1289 5.11e-265 728.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RM93@1236|Gammaproteobacteria,464KF@72275|Alteromonadaceae 1236|Gammaproteobacteria I Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed fadA GO:0003674,GO:0003824,GO:0003988,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 2.3.1.16 ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 M00087,M00113 R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095 RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_2612,iECNA114_1301.ECNA114_4154,iECOK1_1307.ECOK1_4314,iECP_1309.ECP_4058,iECS88_1305.ECS88_4293,iECSF_1327.ECSF_3702,iEcE24377_1341.EcE24377A_4364,iLF82_1304.LF82_0613,iNRG857_1313.NRG857_19195,iPC815.YPO3767 Thiolase_C,Thiolase_N k141_23351_4 1042377.AFPJ01000036_gene1290 5.62e-267 736.0 COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,1RNZE@1236|Gammaproteobacteria,46543@72275|Alteromonadaceae 1236|Gammaproteobacteria D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase tig GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006464,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0042802,GO:0043021,GO:0043022,GO:0043170,GO:0043335,GO:0043412,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0050896,GO:0051083,GO:0061077,GO:0071704,GO:0140096,GO:1901564 - ko:K03545 - - - - ko00000 - - - FKBP_C,Trigger_C,Trigger_N k141_23351_6 1279017.AQYJ01000029_gene3447 3.73e-133 379.0 COG0740@1|root,COG0740@2|Bacteria,1MV46@1224|Proteobacteria,1RNR6@1236|Gammaproteobacteria,46400@72275|Alteromonadaceae 1236|Gammaproteobacteria OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins clpP GO:0000502,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006515,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009266,GO:0009314,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0010498,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017171,GO:0019538,GO:0019899,GO:0030163,GO:0031597,GO:0032991,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0050896,GO:0051117,GO:0051603,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 - - - ko00000,ko00001,ko01000,ko01002 - - - CLP_protease k141_23351_7 1279017.AQYJ01000029_gene3448 2.65e-286 785.0 COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,1RN9N@1236|Gammaproteobacteria,464XT@72275|Alteromonadaceae 1236|Gammaproteobacteria O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP clpX GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043335,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051301,GO:0051704,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - ko:K03544 ko04112,map04112 - - - ko00000,ko00001,ko03110 - - - AAA_2,ClpB_D2-small,zf-C4_ClpX k141_23351_8 1453501.JELR01000001_gene2621 0.0 1399.0 COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,1RPCB@1236|Gammaproteobacteria,464ZC@72275|Alteromonadaceae 1236|Gammaproteobacteria O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner lon GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004175,GO:0004176,GO:0004252,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006515,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009266,GO:0009314,GO:0009408,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0017171,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051603,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 3.4.21.53 ko:K01338 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - AAA,LON_substr_bdg,Lon_C k141_23351_9 1279017.AQYJ01000029_gene3450 1.28e-53 168.0 COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,1S8VH@1236|Gammaproteobacteria,467ZY@72275|Alteromonadaceae 1236|Gammaproteobacteria L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions hupB - - ko:K03530 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding k141_23351_10 1279017.AQYJ01000029_gene3451 2.59e-264 745.0 COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,1RMT5@1236|Gammaproteobacteria,4643B@72275|Alteromonadaceae 1236|Gammaproteobacteria O peptidylprolyl isomerase ppiD GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0008150,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031233,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0061077,GO:0071575,GO:0071944,GO:0098552 5.2.1.8 ko:K03770 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_2,Rotamase_3,SurA_N_3 k141_23351_11 1279017.AQYJ01000029_gene3452 2.32e-286 792.0 COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,1RMFZ@1236|Gammaproteobacteria,464A9@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) mltD GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008932,GO:0008933,GO:0009893,GO:0016020,GO:0016740,GO:0016757,GO:0019222,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043085,GO:0044093,GO:0044464,GO:0048518,GO:0050789,GO:0050790,GO:0051341,GO:0051353,GO:0061783,GO:0065007,GO:0065009 - ko:K08307 - - - - ko00000,ko01000,ko01011 - - - LysM,SLT k141_23351_12 1042377.AFPJ01000031_gene568 2.13e-112 330.0 COG0491@1|root,COG0491@2|Bacteria,1MU8Q@1224|Proteobacteria,1S22I@1236|Gammaproteobacteria,466DR@72275|Alteromonadaceae 1236|Gammaproteobacteria S Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid gloB GO:0003674,GO:0003824,GO:0004416,GO:0006518,GO:0006575,GO:0006749,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0034641,GO:0043603,GO:0044237,GO:0051186,GO:0071704,GO:1901564 3.1.2.6 ko:K01069 ko00620,map00620 - R01736 RC00004,RC00137 ko00000,ko00001,ko01000 - - - HAGH_C,Lactamase_B k141_23351_13 1042377.AFPJ01000031_gene569 6.44e-134 385.0 COG0500@1|root,COG2226@2|Bacteria,1QTWC@1224|Proteobacteria,1RS4G@1236|Gammaproteobacteria,467Q6@72275|Alteromonadaceae 1236|Gammaproteobacteria Q COG0500 SAM-dependent methyltransferases yafS - - - - - - - - - - - Methyltransf_11 k141_23351_14 1279017.AQYJ01000029_gene3455 2.37e-93 273.0 COG0328@1|root,COG0328@2|Bacteria,1RCZ1@1224|Proteobacteria,1S3YC@1236|Gammaproteobacteria,4676A@72275|Alteromonadaceae 1236|Gammaproteobacteria L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhA GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03469 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_H k141_23351_15 1279017.AQYJ01000029_gene3456 1.03e-139 398.0 COG0847@1|root,COG0847@2|Bacteria,1MV8Z@1224|Proteobacteria,1RNHQ@1236|Gammaproteobacteria,46491@72275|Alteromonadaceae 1236|Gammaproteobacteria L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease dnaQ GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016787,GO:0016788,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0045004,GO:0045005,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7,3.1.26.4 ko:K02342,ko:K14159 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - RNase_H,RNase_T k141_9046_1 218284.CCDN010000001_gene1702 2.07e-164 473.0 COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,4HAAP@91061|Bacilli,1ZB4E@1386|Bacillus 91061|Bacilli S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay rnj - - ko:K12574 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - Lactamase_B,Lactamase_B_2,RMMBL k141_29130_1 218284.CCDN010000001_gene1382 1.9e-101 301.0 COG1316@1|root,COG1316@2|Bacteria,1TSWQ@1239|Firmicutes,4HE66@91061|Bacilli,1ZBW5@1386|Bacillus 91061|Bacilli K COG1316 Transcriptional regulator msrR - - - - - - - - - - - LytR_cpsA_psr k141_791_1 1178540.BA70_05290 1.99e-65 213.0 COG1364@1|root,COG1364@2|Bacteria,1TPBP@1239|Firmicutes,4H9TQ@91061|Bacilli,1ZAU3@1386|Bacillus 91061|Bacilli E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate argJ GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R00259,R02282 RC00004,RC00064 ko00000,ko00001,ko00002,ko01000 - - - ArgJ k141_20793_1 1279017.AQYJ01000028_gene2526 6.76e-164 488.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,464D1@72275|Alteromonadaceae 1236|Gammaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K18138,ko:K18303 ko01501,ko01503,map01501,map01503 M00642,M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2,2.A.6.2.17 - - ACR_tran k141_32646_1 218284.CCDN010000006_gene3640 2.29e-91 271.0 COG0118@1|root,COG0118@2|Bacteria,1TQT0@1239|Firmicutes,4HFXQ@91061|Bacilli,1ZBC4@1386|Bacillus 91061|Bacilli E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR hisH GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - - GATase k141_16106_2 1453501.JELR01000001_gene2396 7.7e-26 108.0 COG3975@1|root,COG3975@2|Bacteria,1QX25@1224|Proteobacteria,1RWD8@1236|Gammaproteobacteria,466PD@72275|Alteromonadaceae 1236|Gammaproteobacteria S protease with the C-terminal PDZ domain - - - - - - - - - - - - - k141_10341_1 305900.GV64_19765 1.02e-100 306.0 COG2603@1|root,COG2603@2|Bacteria,1N4T5@1224|Proteobacteria,1RPFP@1236|Gammaproteobacteria,1XIHD@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA selU - - ko:K06917 - - - - ko00000,ko01000,ko03016 - - - Rhodanese k141_23384_1 218284.CCDN010000001_gene150 5.93e-120 347.0 COG0726@1|root,COG0726@2|Bacteria,1TS3D@1239|Firmicutes,4HAVF@91061|Bacilli,1ZC37@1386|Bacillus 91061|Bacilli G Polysaccharide deacetylase pdaA_2 - 3.5.1.104 ko:K01567,ko:K22278 - - - - ko00000,ko01000 - - - Polysacc_deac_1 k141_37430_1 1294265.JCM21738_1707 6.98e-74 221.0 29RMN@1|root,30CQY@2|Bacteria,1UA8H@1239|Firmicutes,4IKJZ@91061|Bacilli,1ZH5K@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_14848_1 1173025.GEI7407_2980 2.37e-43 152.0 COG2230@1|root,COG2230@2|Bacteria,1G3TN@1117|Cyanobacteria,1H8KG@1150|Oscillatoriales 1117|Cyanobacteria M Methylase involved in ubiquinone menaquinone biosynthesis - - - - - - - - - - - - Methyltransf_31 k141_36208_1 218284.CCDN010000001_gene671 1.97e-151 434.0 COG0124@1|root,COG0124@2|Bacteria,1TP3D@1239|Firmicutes,4HAM2@91061|Bacilli,1ZBXR@1386|Bacillus 91061|Bacilli J histidyl-tRNA synthetase hisS - 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_2b,tRNA-synt_His k141_13949_1 935837.JAEK01000020_gene592 1.55e-103 315.0 COG3437@1|root,COG3437@2|Bacteria,1TQ0S@1239|Firmicutes,4HEM3@91061|Bacilli,1ZDPH@1386|Bacillus 91061|Bacilli KT HD domain M1-580 - - - - - - - - - - - GGDEF,HD,HD_5,PAS_3,PAS_9 k141_1744_1 1279017.AQYJ01000021_gene2875 5.56e-124 408.0 COG2911@1|root,COG2911@2|Bacteria 2|Bacteria S protein secretion - - - - - - - - - - - - DctA-YdbH,Peptidase_S74 k141_1744_4 1279017.AQYJ01000021_gene2872 1.14e-201 565.0 COG0568@1|root,COG0568@2|Bacteria,1MUDI@1224|Proteobacteria,1RN8V@1236|Gammaproteobacteria,4641K@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG0568 DNA-directed RNA polymerase, sigma subunit (sigma70 sigma32) rpoS GO:0000988,GO:0000990,GO:0001000,GO:0001121,GO:0001123,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043175,GO:0043254,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - ko:K03087 ko02026,ko05111,map02026,map05111 - - - ko00000,ko00001,ko03021 - - - Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 k141_1744_5 1279017.AQYJ01000021_gene2871 8.57e-101 301.0 COG4942@1|root,COG4942@2|Bacteria,1RD24@1224|Proteobacteria,1RR11@1236|Gammaproteobacteria,466TP@72275|Alteromonadaceae 1236|Gammaproteobacteria D COG0739 Membrane proteins related to metalloendopeptidases nlpD GO:0000920,GO:0001896,GO:0005575,GO:0005623,GO:0008150,GO:0008219,GO:0009279,GO:0009987,GO:0012501,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0043085,GO:0044093,GO:0044462,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071944 - ko:K06194,ko:K12943 - - - - ko00000 1.A.34.1.2 - - LysM,Peptidase_M23 k141_1744_6 1279017.AQYJ01000021_gene2870 1.38e-141 409.0 COG2035@1|root,COG2035@2|Bacteria,1MXVI@1224|Proteobacteria,1RN4B@1236|Gammaproteobacteria,466EX@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF368) - - - ko:K08974 - - - - ko00000 - - - DUF368 k141_1744_8 1279017.AQYJ01000021_gene2868 1.99e-155 445.0 COG0585@1|root,COG0585@2|Bacteria,1MXHD@1224|Proteobacteria,1RPRF@1236|Gammaproteobacteria,465C2@72275|Alteromonadaceae 1236|Gammaproteobacteria J Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs truD GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 ko:K06176 - - - - ko00000,ko01000,ko03016 - - - TruD k141_1744_9 1122197.ATWI01000014_gene70 2.49e-74 226.0 COG0245@1|root,COG0245@2|Bacteria,1MVHA@1224|Proteobacteria,1S3RQ@1236|Gammaproteobacteria,466U9@72275|Alteromonadaceae 1236|Gammaproteobacteria I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) ispF GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008270,GO:0008685,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016849,GO:0030145,GO:0042180,GO:0042181,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.6.1.12 ko:K01770 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05637 RC00002,RC01440 ko00000,ko00001,ko00002,ko01000 - - iPC815.YPO3360 YgbB k141_1744_10 1279017.AQYJ01000021_gene2866 2.41e-104 308.0 COG1211@1|root,COG1211@2|Bacteria,1MY3B@1224|Proteobacteria,1S21S@1236|Gammaproteobacteria,466GI@72275|Alteromonadaceae 1236|Gammaproteobacteria I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) ispD GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0050518,GO:0070567,GO:0071704,GO:1901576 2.7.7.60 ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05633 RC00002 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b2747,iBWG_1329.BWG_2483,iEC55989_1330.EC55989_3019,iECDH10B_1368.ECDH10B_2915,iECDH1ME8569_1439.ECDH1ME8569_2657,iECIAI1_1343.ECIAI1_2848,iECO103_1326.ECO103_3289,iECO111_1330.ECO111_3471,iECO26_1355.ECO26_3816,iECSE_1348.ECSE_2999,iECW_1372.ECW_m2953,iEKO11_1354.EKO11_1022,iEcDH1_1363.EcDH1_0941,iEcE24377_1341.EcE24377A_3048,iEcHS_1320.EcHS_A2885,iEcolC_1368.EcolC_0965,iJO1366.b2747,iJR904.b2747,iPC815.YPO3361,iSBO_1134.SBO_2773,iSDY_1059.SDY_2946,iSSON_1240.SSON_2895,iSbBS512_1146.SbBS512_E3127,iUMNK88_1353.UMNK88_3422,iWFL_1372.ECW_m2953,iY75_1357.Y75_RS14300 IspD k141_1744_11 1042377.AFPJ01000020_gene2049 9.72e-42 139.0 COG2919@1|root,COG2919@2|Bacteria,1N7AA@1224|Proteobacteria,1SD8H@1236|Gammaproteobacteria,46898@72275|Alteromonadaceae 1236|Gammaproteobacteria D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic ftsB GO:0000003,GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0007049,GO:0008150,GO:0009987,GO:0019954,GO:0022402,GO:0022414,GO:0030428,GO:0032153,GO:0032505,GO:0042802,GO:0043093,GO:0044464,GO:0051301 - ko:K05589 - - - - ko00000,ko03036 - - - DivIC k141_1744_13 1453501.JELR01000001_gene2845 7.07e-187 521.0 COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,1RMGQ@1236|Gammaproteobacteria,4661I@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the KdsA family kdsA GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005996,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008676,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016043,GO:0016051,GO:0016053,GO:0016740,GO:0016765,GO:0019294,GO:0019752,GO:0022607,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046394,GO:0046400,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.5.1.55 ko:K01627 ko00540,ko01100,map00540,map01100 M00063 R03254 RC00435 ko00000,ko00001,ko00002,ko01000,ko01005 - - - DAHP_synth_1 k141_1744_14 1279017.AQYJ01000021_gene2862 0.0 1027.0 COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,1RM92@1236|Gammaproteobacteria,4646Z@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates pyrG GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 - - iECO103_1326.ECO103_3323,iPC815.YPO3377 CTP_synth_N,GATase k141_1744_15 377629.TERTU_2852 4.13e-108 333.0 COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,1RN14@1236|Gammaproteobacteria,2PNEG@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria D TilS substrate C-terminal domain tilS GO:0002097,GO:0002101,GO:0002136,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016879,GO:0032267,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 6.3.4.19 ko:K04075 - - R09597 RC02633,RC02634 ko00000,ko01000,ko03016 - - - ATP_bind_3,TilS,TilS_C k141_9061_1 675812.VHA_002560 4.21e-193 555.0 COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,1RPSJ@1236|Gammaproteobacteria,1XTPG@135623|Vibrionales 135623|Vibrionales T containing cAMP-binding and CBS domains - - - ko:K07182 - - - - ko00000 - - - CBS,DUF294,DUF294_C,cNMP_binding k141_6650_1 309798.COPRO5265_1474 4.82e-43 180.0 COG1404@1|root,COG1404@2|Bacteria,1TQRU@1239|Firmicutes,249H1@186801|Clostridia,42FS7@68295|Thermoanaerobacterales 186801|Clostridia M Serine protease with a broad substrate specificity - - - ko:K13276,ko:K17734 - - - - ko00000,ko01000,ko01002,ko03110 - - - CarboxypepD_reg,Cu_amine_oxidN1,Inhibitor_I9,LRR_5,PPC,Peptidase_S8 k141_6650_3 1453501.JELR01000002_gene1494 2.27e-128 372.0 COG3672@1|root,COG3672@2|Bacteria,1RKG9@1224|Proteobacteria,1S8MS@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Periplasmic Protein - - - - - - - - - - - - Transglut_core k141_6650_4 1042377.AFPJ01000032_gene2728 5.58e-35 120.0 2EBER@1|root,335FA@2|Bacteria,1NDX3@1224|Proteobacteria,1SEUR@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - DUF350 k141_6650_5 1453501.JELR01000002_gene1492 0.0 1178.0 COG1913@1|root,COG1913@2|Bacteria,1MY52@1224|Proteobacteria,1RSIP@1236|Gammaproteobacteria,4646U@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF5117) - - - - - - - - - - - - DUF4953,DUF5117 k141_6650_6 1279017.AQYJ01000028_gene2092 8.3e-63 204.0 28HMH@1|root,2Z7W2@2|Bacteria,1R7XG@1224|Proteobacteria,1S0FH@1236|Gammaproteobacteria,46DP2@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF2884) VP2339 - - - - - - - - - - - DUF2884 k141_6650_7 435908.IDSA_08120 1.05e-82 261.0 COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria,2QGM7@267893|Idiomarinaceae 1236|Gammaproteobacteria O PA domain - - - - - - - - - - - - PA,PKD,Peptidase_S8 k141_22046_1 1134474.O59_003624 3.56e-99 317.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MV8W@1224|Proteobacteria,1RMQA@1236|Gammaproteobacteria,1FHXR@10|Cellvibrio 1236|Gammaproteobacteria P Outer membrane protein beta-barrel family - - - - - - - - - - - - Plug,TonB_dep_Rec k141_12758_1 218284.CCDN010000001_gene731 1.58e-57 189.0 COG0635@1|root,COG0635@2|Bacteria,1TPES@1239|Firmicutes,4HA60@91061|Bacilli,1ZC7V@1386|Bacillus 91061|Bacilli H Involved in the biosynthesis of porphyrin-containing compound hemN GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - - - - - - - - - - HemN_C,Radical_SAM k141_12758_2 218284.CCDN010000001_gene732 1.38e-156 444.0 COG1420@1|root,COG1420@2|Bacteria,1TQP7@1239|Firmicutes,4HAX5@91061|Bacilli,1ZBQV@1386|Bacillus 91061|Bacilli K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons hrcA GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K03705 - - - - ko00000,ko03000 - - - HrcA,HrcA_DNA-bdg k141_11498_1 218284.CCDN010000001_gene1460 4.06e-100 305.0 COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HA2G@91061|Bacilli,1ZC9Y@1386|Bacillus 91061|Bacilli IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding,AMP-binding_C k141_13950_1 765914.ThisiDRAFT_1732 7.05e-30 113.0 COG0483@1|root,COG0483@2|Bacteria,1PPJ0@1224|Proteobacteria,1RMVD@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Inositol monophosphatase - - 3.1.3.15 ko:K05602 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R03013 RC00017 ko00000,ko00001,ko00002,ko01000 - - - Inositol_P k141_10342_1 218284.CCDN010000002_gene2217 1.86e-75 228.0 2DN3I@1|root,32VBH@2|Bacteria,1VB51@1239|Firmicutes,4HKZM@91061|Bacilli,1ZI4Y@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_23385_1 218284.CCDN010000007_gene3911 2.54e-123 366.0 COG1292@1|root,COG1292@2|Bacteria,1TRS6@1239|Firmicutes,4HA7U@91061|Bacilli,1ZBRN@1386|Bacillus 91061|Bacilli M Belongs to the BCCT transporter (TC 2.A.15) family opuD_3 - - - - - - - - - - - BCCT k141_2964_1 1453501.JELR01000002_gene944 7.73e-61 191.0 COG0703@1|root,COG0703@2|Bacteria,1MUFJ@1224|Proteobacteria,1RPF6@1236|Gammaproteobacteria,467A5@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate aroK GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - SKI k141_25776_1 218284.CCDN010000001_gene1310 2.2e-43 153.0 28N49@1|root,2ZB9S@2|Bacteria,1UY59@1239|Firmicutes,4HBU7@91061|Bacilli,1ZG1M@1386|Bacillus 91061|Bacilli S Spore germination B3/ GerAC like, C-terminal gerKC - - - - - - - - - - - Spore_GerAC k141_20794_1 1347369.CCAD010000086_gene1731 2.52e-67 213.0 COG0596@1|root,COG0596@2|Bacteria,1U4P9@1239|Firmicutes,4HMUK@91061|Bacilli,1ZEJG@1386|Bacillus 91061|Bacilli S BAAT / Acyl-CoA thioester hydrolase C terminal - - - - - - - - - - - - Abhydrolase_1 k141_1745_1 1131730.BAVI_20618 1.37e-143 413.0 COG2718@1|root,COG2718@2|Bacteria,1TQIN@1239|Firmicutes,4HBIH@91061|Bacilli,1ZATH@1386|Bacillus 91061|Bacilli S Belongs to the UPF0229 family yhbH - - ko:K09786 - - - - ko00000 - - - DUF444 k141_27089_1 218284.CCDN010000007_gene3897 3.65e-123 357.0 COG0190@1|root,COG0190@2|Bacteria,1TP1P@1239|Firmicutes,4H9Q6@91061|Bacilli,1ZC9G@1386|Bacillus 91061|Bacilli F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate folD GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R01220,R01655 RC00202,RC00578 ko00000,ko00001,ko00002,ko01000 - - - THF_DHG_CYH,THF_DHG_CYH_C k141_24457_1 1307436.PBF_17284 1.21e-46 158.0 COG0157@1|root,COG0157@2|Bacteria,1TPQC@1239|Firmicutes,4HB46@91061|Bacilli,1ZBVN@1386|Bacillus 91061|Bacilli H Belongs to the NadC ModD family nadC GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034213,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 2.4.2.19 ko:K00767 ko00760,ko01100,map00760,map01100 M00115 R03348 RC02877 ko00000,ko00001,ko00002,ko01000 - - - QRPTase_C,QRPTase_N k141_9062_1 218284.CCDN010000001_gene574 2.56e-99 302.0 COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,4HADX@91061|Bacilli,1ZDA6@1386|Bacillus 91061|Bacilli E Belongs to the aspartokinase family lysC GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,ACT,ACT_7 k141_29142_2 1042377.AFPJ01000036_gene1171 1.61e-30 114.0 COG3823@1|root,COG3823@2|Bacteria,1R9YU@1224|Proteobacteria,1RZ5N@1236|Gammaproteobacteria,4679T@72275|Alteromonadaceae 1236|Gammaproteobacteria O Glutamine cyclotransferase - - 2.3.2.5 ko:K00683 - - - - ko00000,ko01000 - - - Glu_cyclase_2 k141_27848_1 218284.CCDN010000010_gene4374 1.34e-219 638.0 COG0085@1|root,COG0085@2|Bacteria,1TP96@1239|Firmicutes,4H9PK@91061|Bacilli,1ZBPC@1386|Bacillus 91061|Bacilli K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoB GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 k141_23386_1 1453501.JELR01000002_gene824 5.15e-87 281.0 COG3866@1|root,COG4733@1|root,COG3866@2|Bacteria,COG4733@2|Bacteria,1RGJR@1224|Proteobacteria,1S4RB@1236|Gammaproteobacteria,467IC@72275|Alteromonadaceae 1236|Gammaproteobacteria G Pectate lyase - - - - - - - - - - - - fn3 k141_14849_1 218284.CCDN010000006_gene3528 1.06e-83 261.0 COG0619@1|root,COG0619@2|Bacteria,1VBW7@1239|Firmicutes,4HB6S@91061|Bacilli,1ZS19@1386|Bacillus 91061|Bacilli P Spore gernimation protein GerA - - - - - - - - - - - - GerA k141_35219_1 1294265.JCM21738_4820 3.04e-122 357.0 COG2733@1|root,COG2733@2|Bacteria,1TS8F@1239|Firmicutes,4HC8U@91061|Bacilli,1ZCND@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF445) - - - - - - - - - - - - DUF445 k141_1746_1 1298867.AUES01000009_gene5904 3.84e-11 67.8 COG1208@1|root,COG1208@2|Bacteria,1R9ZD@1224|Proteobacteria,2TU2V@28211|Alphaproteobacteria,3JRYE@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria JM Nucleotidyl transferase MA20_24100 - 2.7.7.13,2.7.7.99 ko:K00966,ko:K00992 ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110 M00114,M00361,M00362 R00885,R11025 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transf_3,NTP_transferase k141_17269_2 1279017.AQYJ01000029_gene3423 2e-260 729.0 COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,1RNIY@1236|Gammaproteobacteria,4644H@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine sufS - 2.8.1.7,4.4.1.16 ko:K11717 ko00450,ko01100,map00450,map01100 - R03599,R11528 RC00961,RC01789,RC02313 ko00000,ko00001,ko01000 - - - Aminotran_5,SufE k141_17269_3 1279017.AQYJ01000029_gene3426 1.71e-145 415.0 COG1179@1|root,COG1179@2|Bacteria,1MWXR@1224|Proteobacteria,1RMT3@1236|Gammaproteobacteria,464BI@72275|Alteromonadaceae 1236|Gammaproteobacteria H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 ygdL GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016829,GO:0016835,GO:0016836,GO:0030955,GO:0031402,GO:0031420,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0061503,GO:0061504,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 - ko:K22132 - - - - ko00000,ko03016 - - - ThiF k141_17269_4 743720.Psefu_1755 8.42e-48 158.0 COG3011@1|root,COG3011@2|Bacteria,1N2CU@1224|Proteobacteria,1TAN1@1236|Gammaproteobacteria,1YZ5B@136845|Pseudomonas putida group 1236|Gammaproteobacteria S Protein of unknown function, DUF393 - - - - - - - - - - - - DUF393 k141_17269_8 1279017.AQYJ01000029_gene3431 2.93e-28 116.0 COG3595@1|root,COG3595@2|Bacteria,1N9QF@1224|Proteobacteria,1SFT4@1236|Gammaproteobacteria,46C9Z@72275|Alteromonadaceae 1236|Gammaproteobacteria S Putative auto-transporter adhesin, head GIN domain - - - - - - - - - - - - DUF2807 k141_17269_9 1279017.AQYJ01000029_gene3432 9.8e-255 709.0 COG3106@1|root,COG3106@2|Bacteria,1MX6E@1224|Proteobacteria,1RQ05@1236|Gammaproteobacteria,464CF@72275|Alteromonadaceae 1236|Gammaproteobacteria S YcjX-like family, DUF463 ycjX - - ko:K06918 - - - - ko00000 - - - DUF463 k141_17269_10 1453501.JELR01000001_gene2636 2.8e-186 528.0 COG3768@1|root,COG3768@2|Bacteria,1MU8S@1224|Proteobacteria,1RND9@1236|Gammaproteobacteria,467RT@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF697) ycjF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K08990 - - - - ko00000 - - - DUF697 k141_17269_11 1123073.KB899241_gene1753 3.89e-29 114.0 COG3832@1|root,COG3832@2|Bacteria,1N2PR@1224|Proteobacteria,1S71Z@1236|Gammaproteobacteria,1X850@135614|Xanthomonadales 135614|Xanthomonadales S Polyketide cyclase / dehydrase and lipid transport - - - - - - - - - - - - Polyketide_cyc2 k141_17269_12 1042377.AFPJ01000036_gene1279 2.91e-74 226.0 2E0SQ@1|root,32WAM@2|Bacteria,1MZWQ@1224|Proteobacteria,1S9A4@1236|Gammaproteobacteria,468C1@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_17269_13 1279017.AQYJ01000029_gene3435 2.19e-269 744.0 COG1249@1|root,COG1249@2|Bacteria,1MU2Z@1224|Proteobacteria,1RMC0@1236|Gammaproteobacteria,46406@72275|Alteromonadaceae 1236|Gammaproteobacteria C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family gor GO:0000166,GO:0003674,GO:0003824,GO:0004362,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015036,GO:0015037,GO:0015038,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071949,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.7 ko:K00383 ko00480,ko04918,map00480,map04918 - R00094,R00115 RC00011 ko00000,ko00001,ko01000 - - iZ_1308.Z4900 Pyr_redox_2,Pyr_redox_dim k141_14258_2 218284.CCDN010000001_gene601 5.6e-171 480.0 COG0755@1|root,COG0755@2|Bacteria,1U8IP@1239|Firmicutes,4HD6H@91061|Bacilli,1ZBFP@1386|Bacillus 91061|Bacilli O cytochrome C hemX GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008152,GO:0015886,GO:0016020,GO:0044464,GO:0051179,GO:0051181,GO:0051234,GO:0055114,GO:0071702,GO:0071705,GO:0071944,GO:1901678 - ko:K02497 - - - - ko00000 - - - Cytochrom_C_asm k141_22359_1 265729.GS18_0201165 1.02e-174 492.0 COG4209@1|root,COG4209@2|Bacteria,1TP33@1239|Firmicutes,4HATZ@91061|Bacilli,1ZAQ3@1386|Bacillus 91061|Bacilli G COG4209 ABC-type polysaccharide transport system, permease component - - - ko:K17319 ko02010,map02010 M00603 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.29,3.A.1.1.9 - - BPD_transp_1 k141_16298_1 204669.Acid345_4549 3.02e-60 209.0 COG1197@1|root,COG1197@2|Bacteria,3Y3IE@57723|Acidobacteria,2JIHQ@204432|Acidobacteriia 204432|Acidobacteriia L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd - - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF k141_34186_1 1196031.ALEG01000036_gene3961 8.99e-71 216.0 COG2764@1|root,COG2764@2|Bacteria,1V3WE@1239|Firmicutes,4HHHS@91061|Bacilli,1ZGHJ@1386|Bacillus 91061|Bacilli S protein conserved in bacteria - - - ko:K04750 - - - - ko00000 - - - 3-dmu-9_3-mt,Glyoxalase k141_4376_1 218284.CCDN010000004_gene3044 1.1e-151 436.0 COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,4HACR@91061|Bacilli,1ZCC3@1386|Bacillus 91061|Bacilli M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein murF - 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 - R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M k141_9368_1 218284.CCDN010000002_gene2939 1.94e-136 392.0 COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,4HA4E@91061|Bacilli,1ZB72@1386|Bacillus 91061|Bacilli P Belongs to the ABC transporter superfamily - - - ko:K02031 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - ABC_tran,oligo_HPY k141_10447_1 491915.Aflv_1532 3.62e-60 192.0 COG0558@1|root,COG0558@2|Bacteria,1V6PJ@1239|Firmicutes,4HCEX@91061|Bacilli,21WUX@150247|Anoxybacillus 91061|Bacilli I CDP-alcohol phosphatidyltransferase pgsA GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 2.7.8.5 ko:K00995 ko00564,ko01100,map00564,map01100 - R01801 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 - - iSB619.SA_RS06365 CDP-OH_P_transf k141_12908_1 218284.CCDN010000001_gene957 8.59e-82 253.0 2C2CG@1|root,2Z7PW@2|Bacteria,1TQQ2@1239|Firmicutes,4H9UX@91061|Bacilli,1ZCFI@1386|Bacillus 91061|Bacilli S stage III sporulation protein AE spoIIIAE - - ko:K06394 - - - - ko00000 - - - Spore_III_AE k141_35449_1 218284.CCDN010000008_gene4187 3.92e-28 102.0 2EJ4P@1|root,33CVX@2|Bacteria,1VMH9@1239|Firmicutes,4HSGS@91061|Bacilli,1ZIVZ@1386|Bacillus 91061|Bacilli S Sporulation protein Cse60 yteV - - - - - - - - - - - Spore_Cse60 k141_16299_2 218284.CCDN010000005_gene3231 1.21e-39 132.0 2DP0U@1|root,3302E@2|Bacteria,1VHZ7@1239|Firmicutes,4HNJQ@91061|Bacilli,1ZIWY@1386|Bacillus 91061|Bacilli S Spore germination protein gerPA/gerPF gerPF - - ko:K06299,ko:K06304 - - - - ko00000 - - - gerPA k141_34187_1 1294265.JCM21738_2414 2.52e-80 241.0 COG0609@1|root,COG0609@2|Bacteria,1TPX6@1239|Firmicutes,4HAUK@91061|Bacilli,1ZNIC@1386|Bacillus 91061|Bacilli P FecCD transport family btuC - - ko:K02015 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - iYO844.BSU33170 FecCD k141_9369_1 1047013.AQSP01000139_gene2337 2.63e-55 182.0 COG1392@1|root,COG1392@2|Bacteria 2|Bacteria P Protein of unknown function DUF47 CP_0066 - - ko:K07220 - - - - ko00000 - - - PhoU_div k141_30361_1 218284.CCDN010000001_gene669 1.59e-92 288.0 COG0860@1|root,COG3103@1|root,COG3807@1|root,COG0860@2|Bacteria,COG3103@2|Bacteria,COG3807@2|Bacteria,1UYPW@1239|Firmicutes,4HBVT@91061|Bacilli,1ZDI1@1386|Bacillus 91061|Bacilli M COG3103 SH3 domain protein lytH GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - Amidase_3,SH3_3 k141_18988_2 218284.CCDN010000005_gene3461 5.27e-102 296.0 COG1522@1|root,COG1522@2|Bacteria,1V3PB@1239|Firmicutes,4HH9K@91061|Bacilli,1ZFM5@1386|Bacillus 91061|Bacilli K Transcriptional regulator alaR - - - - - - - - - - - AsnC_trans_reg,HTH_24 k141_15066_1 1384057.CD33_09395 2.11e-21 90.5 COG1556@1|root,COG1556@2|Bacteria,1UZAK@1239|Firmicutes,4HH3R@91061|Bacilli,3IWHP@400634|Lysinibacillus 91061|Bacilli S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source lutC - - ko:K00782 - - - - ko00000 - - - LUD_dom k141_15066_2 935836.JAEL01000083_gene1122 1.97e-141 410.0 COG1139@1|root,COG1139@2|Bacteria,1TREQ@1239|Firmicutes,4H9UI@91061|Bacilli,1ZCJB@1386|Bacillus 91061|Bacilli C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate lutB - - ko:K18929 - - - - ko00000 - - - DUF3390,Fer4_8,LUD_dom k141_6954_1 218284.CCDN010000008_gene4137 1.53e-123 374.0 COG0058@1|root,COG0058@2|Bacteria,1TQAJ@1239|Firmicutes,4H9XI@91061|Bacilli,1ZCRF@1386|Bacillus 91061|Bacilli G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties glgP GO:0000272,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005976,GO:0005977,GO:0005980,GO:0006073,GO:0006091,GO:0006112,GO:0008144,GO:0008150,GO:0008152,GO:0008184,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0015980,GO:0016052,GO:0016740,GO:0016757,GO:0016758,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901575 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 - R02111 - ko00000,ko00001,ko01000 - GT35 iYO844.BSU30940 Phosphorylase k141_24681_1 1294265.JCM21738_1579 1.5e-88 261.0 COG3773@1|root,COG3773@2|Bacteria,1V43B@1239|Firmicutes,4HJXG@91061|Bacilli,1ZERM@1386|Bacillus 91061|Bacilli M COG3773 Cell wall hydrolyses involved in spore germination - - 3.5.1.28 ko:K01449 - - R04112 RC00064,RC00141 ko00000,ko01000 - - - Hydrolase_2,LysM k141_20944_1 1177181.T9A_01786 7.23e-11 64.3 2ENKU@1|root,33G87@2|Bacteria,1NMH6@1224|Proteobacteria,1SGDI@1236|Gammaproteobacteria,1XMTM@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_4393_1 1042377.AFPJ01000030_gene447 7.48e-147 441.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MV8W@1224|Proteobacteria,1RMQA@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Outer membrane receptor proteins mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec k141_31526_1 1042377.AFPJ01000024_gene768 4.05e-92 277.0 COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,1RPTA@1236|Gammaproteobacteria,464JQ@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0451 Nucleoside-diphosphate-sugar epimerases capI - 5.1.3.25,5.1.3.6 ko:K08679,ko:K17947 ko00520,ko00523,ko01100,ko01130,map00520,map00523,map01100,map01130 - R01385,R10279 RC00289 ko00000,ko00001,ko01000 - - - Epimerase,GDP_Man_Dehyd k141_31526_2 550540.Fbal_0149 1e-16 79.3 COG3642@1|root,COG3642@2|Bacteria,1RDW7@1224|Proteobacteria,1S46R@1236|Gammaproteobacteria 1236|Gammaproteobacteria H Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position kdkA - 2.7.1.166 ko:K11211 ko00540,map00540 - R09767 RC00002,RC00078 ko00000,ko00001,ko01000 - - - Kdo k141_6996_1 1385514.N782_11315 1.09e-237 673.0 COG4412@1|root,COG4412@2|Bacteria,1TQYP@1239|Firmicutes,4HD82@91061|Bacilli,2YA1P@289201|Pontibacillus 91061|Bacilli S protease - - - ko:K09607 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M6 k141_9389_2 218284.CCDN010000005_gene3476 1.94e-54 180.0 COG1979@1|root,COG1979@2|Bacteria,1TPS3@1239|Firmicutes,4H9TR@91061|Bacilli,1ZBKF@1386|Bacillus 91061|Bacilli C oxidoreductases, Fe-dependent alcohol dehydrogenase family yugJ - - ko:K19955 - - - - ko00000,ko01000 - - - Fe-ADH k141_28006_2 1042377.AFPJ01000037_gene2845 3.34e-173 491.0 COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,1RMMS@1236|Gammaproteobacteria,4643H@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the ferrous insertion into protoporphyrin IX hemH GO:0003674,GO:0003824,GO:0004325,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009314,GO:0009416,GO:0009628,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0050896,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R00310,R11329 RC01012 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_1540,iECS88_1305.ECS88_0472,iEcE24377_1341.EcE24377A_0515 Ferrochelatase k141_28006_3 1453501.JELR01000001_gene1996 1.8e-137 390.0 COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,1RMT6@1236|Gammaproteobacteria,46577@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism adk GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004017,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006412,GO:0006518,GO:0006629,GO:0006644,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0010467,GO:0015949,GO:0015950,GO:0015951,GO:0016070,GO:0016208,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019205,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 - - iECH74115_1262.ECH74115_0566,iEKO11_1354.EKO11_3373,iG2583_1286.G2583_0586,iJN746.PP_1506 ADK,ADK_lid k141_28006_4 59538.XP_005976601.1 2.85e-92 281.0 COG0111@1|root,KOG0068@2759|Eukaryota,38GJA@33154|Opisthokonta,3BEWZ@33208|Metazoa,3CTJ7@33213|Bilateria,484RB@7711|Chordata,494HT@7742|Vertebrata 33208|Metazoa E phosphoglycerate dehydrogenase activity - - 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C k141_11754_1 218284.CCDN010000001_gene637 4.91e-128 374.0 COG0536@1|root,COG0536@2|Bacteria,1TPX7@1239|Firmicutes,4H9P8@91061|Bacilli,1ZCM4@1386|Bacillus 91061|Bacilli S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control obg GO:0000003,GO:0000160,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0017076,GO:0019001,GO:0019954,GO:0023052,GO:0030436,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035556,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043934,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03979 - - - - ko00000,ko01000,ko03009 - - - DUF1967,GTP1_OBG,MMR_HSR1 k141_20963_1 1279017.AQYJ01000028_gene2333 1.04e-119 357.0 COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,1RN3V@1236|Gammaproteobacteria,463ZU@72275|Alteromonadaceae 1236|Gammaproteobacteria FP Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the stringent response , an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities gppA - 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 - R03409 RC00002 ko00000,ko00001,ko01000 - - - HD,Ppx-GppA k141_37596_1 195105.CN97_00345 1.63e-06 49.7 COG0336@1|root,COG0336@2|Bacteria,1MUN1@1224|Proteobacteria,2TSIZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Belongs to the RNA methyltransferase TrmD family trmD GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 ko:K00554 - - R00597 RC00003,RC00334 ko00000,ko01000,ko03016 - - - tRNA_m1G_MT k141_37596_2 1120972.AUMH01000011_gene239 6.84e-50 161.0 COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,4HIK3@91061|Bacilli,278F5@186823|Alicyclobacillaceae 91061|Bacilli J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site rplS GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02884 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L19 k141_15095_1 1167006.UWK_01965 1.79e-52 182.0 COG3594@1|root,COG3594@2|Bacteria,1RGHJ@1224|Proteobacteria 1224|Proteobacteria G Acyltransferase family pslL - - ko:K21005 ko02025,map02025 - - - ko00000,ko00001 - - - Acyl_transf_3 k141_15095_2 1348635.BBJY01000003_gene3873 1.64e-239 659.0 COG0620@1|root,COG0620@2|Bacteria,1MUI9@1224|Proteobacteria,1RMBA@1236|Gammaproteobacteria,1XUR9@135623|Vibrionales 135623|Vibrionales E COG0620 Methionine synthase II (cobalamin-independent) metE - 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_2 k141_15095_3 1348635.BBJY01000003_gene3874 3.41e-211 586.0 28H5S@1|root,2Z7IA@2|Bacteria,1MX3X@1224|Proteobacteria,1RPVF@1236|Gammaproteobacteria,1XU4F@135623|Vibrionales 135623|Vibrionales S Domain of unknown function (DUF1852) - - - - - - - - - - - - DUF1852 k141_15095_4 1348635.BBJY01000023_gene2027 1.53e-218 622.0 COG2199@1|root,COG3706@2|Bacteria 2|Bacteria T GGDEF domain - - - - - - - - - - - - GAF_2,GGDEF,PAS_3,PAS_4,PAS_9,Response_reg k141_26024_1 1122176.KB903532_gene2668 1.12e-13 73.2 COG1574@1|root,COG1574@2|Bacteria,4NFMV@976|Bacteroidetes,1IPIC@117747|Sphingobacteriia 976|Bacteroidetes S Amidohydrolase family - - - - - - - - - - - - Amidohydro_3 k141_26024_2 1116375.VEJY3_08310 3.26e-89 263.0 28I53@1|root,2Z88I@2|Bacteria,1NE5N@1224|Proteobacteria,1RP35@1236|Gammaproteobacteria,1Y03I@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF3750) - - - - - - - - - - - - DUF3750 k141_1026_1 218284.CCDN010000001_gene1115 7.7e-88 268.0 COG0337@1|root,COG0337@2|Bacteria,1TPKZ@1239|Firmicutes,4HAKN@91061|Bacilli,1ZC9C@1386|Bacillus 91061|Bacilli E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) aroB - 4.2.3.4 ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03083 RC00847 ko00000,ko00001,ko00002,ko01000 - - - DHQ_synthase k141_1925_2 748247.AZKH_1669 7.21e-108 318.0 COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,2VJ7G@28216|Betaproteobacteria 28216|Betaproteobacteria V abc transporter - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_1925_3 240016.ABIZ01000001_gene1413 4.67e-90 281.0 COG3174@1|root,COG3174@2|Bacteria,46VTJ@74201|Verrucomicrobia 74201|Verrucomicrobia S Domain of unknown function (DUF4010) - - - - - - - - - - - - DUF4010,MgtC k141_34202_1 1132442.KB889752_gene2725 7.43e-42 152.0 COG1807@1|root,COG1807@2|Bacteria,1TR0R@1239|Firmicutes,4HBI2@91061|Bacilli,1ZET9@1386|Bacillus 91061|Bacilli M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - - - - - - - - - - PMT_2 k141_22397_1 649639.Bcell_2606 4.84e-145 423.0 COG3547@1|root,COG3547@2|Bacteria,1TQP6@1239|Firmicutes,4HDSE@91061|Bacilli,1ZBJW@1386|Bacillus 91061|Bacilli L transposase IS116 IS110 IS902 family protein - - - - - - - - - - - - DEDD_Tnp_IS110,Transposase_20 k141_24712_1 218284.CCDN010000006_gene3512 1.12e-154 449.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HB0J@91061|Bacilli,1ZBUU@1386|Bacillus 91061|Bacilli I acyl-CoA dehydrogenase fadE - 1.3.8.1 ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 - R01175,R01178,R02661,R03172,R04751 RC00052,RC00068,RC00076,RC00120,RC00148 ko00000,ko00001,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_29374_1 1116375.VEJY3_02160 9.86e-71 222.0 COG1270@1|root,COG1270@2|Bacteria,1MURM@1224|Proteobacteria,1S6W4@1236|Gammaproteobacteria,1XSVK@135623|Vibrionales 135623|Vibrionales H COG1270 Cobalamin biosynthesis protein CobD CbiB - - 6.3.1.10 ko:K02227 ko00860,ko01100,map00860,map01100 M00122 R06529,R07302 RC00090,RC00096 ko00000,ko00001,ko00002,ko01000 - - - CobD_Cbib k141_29374_2 223926.28805462 3.65e-155 436.0 COG0775@1|root,COG0775@2|Bacteria,1MY5S@1224|Proteobacteria,1RNSF@1236|Gammaproteobacteria,1XTZ2@135623|Vibrionales 135623|Vibrionales F Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively mtnN GO:0003674,GO:0003824,GO:0008477,GO:0008782,GO:0008930,GO:0016787,GO:0016798,GO:0016799 3.2.2.9 ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 M00034,M00609 R00194,R01401 RC00063,RC00318 ko00000,ko00001,ko00002,ko01000 - - - PNP_UDP_1 k141_29374_3 1116375.VEJY3_02170 1.35e-69 212.0 COG4446@1|root,COG4446@2|Bacteria,1N7IZ@1224|Proteobacteria,1SCZH@1236|Gammaproteobacteria,1XXE2@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria - - - - - - - - - - - - DUF1499 k141_29374_4 1116375.VEJY3_02175 0.0 946.0 COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,1RMY7@1236|Gammaproteobacteria,1XV02@135623|Vibrionales 135623|Vibrionales C COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases gltD - 1.4.1.13,1.4.1.14 ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - Fer4_20,Pyr_redox_2 k141_29374_5 1116375.VEJY3_02180 0.0 2529.0 COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,1RN2W@1236|Gammaproteobacteria,1XSWZ@135623|Vibrionales 135623|Vibrionales E Glutamate synthase gltB - 1.4.1.13,1.4.1.14 ko:K00265 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - GATase_2,GXGXG,Glu_syn_central,Glu_synthase k141_32904_1 1453501.JELR01000002_gene328 3.77e-265 752.0 COG1629@1|root,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria,4651V@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec k141_3204_1 1219076.N646_4566 2.05e-76 239.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1XTGW@135623|Vibrionales 135623|Vibrionales JKL Belongs to the DEAD box helicase family - - - - - - - - - - - - DEAD,Helicase_C k141_22398_1 1096756.ATKN01000015_gene930 4.19e-14 72.8 COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,2GJ11@201174|Actinobacteria,1W7PN@1268|Micrococcaceae 201174|Actinobacteria E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor gcvP - 1.4.4.2 ko:K00281,ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko00002,ko01000 - - - GDC-P k141_22398_2 1288826.MSNKSG1_18205 1.63e-34 122.0 COG0509@1|root,COG0509@2|Bacteria,1RGV7@1224|Proteobacteria,1S656@1236|Gammaproteobacteria,466ZQ@72275|Alteromonadaceae 1236|Gammaproteobacteria E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein gcvH - - ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 - - - GCV_H k141_11756_1 1229276.DI53_2291 5.41e-35 134.0 COG0654@1|root,COG0654@2|Bacteria,4NGIU@976|Bacteroidetes,1IQVK@117747|Sphingobacteriia 976|Bacteroidetes CH FAD binding domain - - - - - - - - - - - - FAD_binding_3 k141_1027_1 946235.CAER01000041_gene2132 5.84e-31 114.0 293T3@1|root,2ZR8H@2|Bacteria,1VDAS@1239|Firmicutes,4HVU1@91061|Bacilli,23NIW@182709|Oceanobacillus 91061|Bacilli S Protein of unknown function (DUF2975) - - - - - - - - - - - - DUF2975 k141_1027_2 218284.CCDN010000001_gene452 7.45e-12 63.9 COG0546@1|root,COG0546@2|Bacteria,1V6BF@1239|Firmicutes,4HC3F@91061|Bacilli,1ZEAH@1386|Bacillus 91061|Bacilli F haloacid dehalogenase-like hydrolase - - 3.2.2.9 ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 M00034,M00609 R00194,R01401 RC00063,RC00318 ko00000,ko00001,ko00002,ko01000 - - - HAD_2 k141_29375_1 218284.CCDN010000002_gene2039 4.7e-86 260.0 COG1366@1|root,COG1366@2|Bacteria,1V326@1239|Firmicutes,4HGFQ@91061|Bacilli,1ZPXD@1386|Bacillus 91061|Bacilli T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) - - - - - - - - - - - - STAS k141_36376_1 218284.CCDN010000002_gene2941 1.55e-121 361.0 COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,4HAM7@91061|Bacilli,1ZBG8@1386|Bacillus 91061|Bacilli E COG0747 ABC-type dipeptide transport system, periplasmic component dppA - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 k141_36376_2 218284.CCDN010000002_gene2940 3.23e-157 445.0 COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,4H9YB@91061|Bacilli,1ZBA4@1386|Bacillus 91061|Bacilli E Belongs to the ABC transporter superfamily appF - - ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY k141_26025_1 1118153.MOY_09407 5.54e-06 47.0 COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,1RNJV@1236|Gammaproteobacteria,1XHSE@135619|Oceanospirillales 135619|Oceanospirillales U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently secY - - ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5 - - SecY k141_26025_2 42565.FP66_06590 5.18e-92 270.0 COG0200@1|root,COG0200@2|Bacteria,1RDC8@1224|Proteobacteria,1S3P6@1236|Gammaproteobacteria,1XJJ2@135619|Oceanospirillales 135619|Oceanospirillales J Binds to the 23S rRNA rplO - - ko:K02876 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27A k141_26025_3 1397528.Q671_13725 4.72e-34 117.0 COG1841@1|root,COG1841@2|Bacteria,1N6ZE@1224|Proteobacteria,1SC8N@1236|Gammaproteobacteria,1XM99@135619|Oceanospirillales 135619|Oceanospirillales J Ribosomal protein L30 rpmD - - ko:K02907 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L30 k141_16327_1 1116375.VEJY3_06080 2.6e-67 206.0 2BZUK@1|root,32RU7@2|Bacteria,1RM0J@1224|Proteobacteria,1S7RF@1236|Gammaproteobacteria,1XXI6@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_28008_1 1042375.AFPL01000032_gene1022 5.73e-18 87.8 COG2207@1|root,COG2207@2|Bacteria,1MX23@1224|Proteobacteria,1S67X@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Arabinose-binding domain of AraC transcription regulator, N-term - - - - - - - - - - - - Arabinose_bd,HTH_18 k141_10461_1 218284.CCDN010000001_gene1293 4.48e-110 325.0 2CEJD@1|root,2Z81V@2|Bacteria,1UD9R@1239|Firmicutes,4HAPP@91061|Bacilli,1ZC32@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3900) yetN - - - - - - - - - - - DUF3898,DUF3900 k141_10461_2 1423321.AS29_07105 5.79e-10 59.3 COG0454@1|root,COG0456@2|Bacteria,1V4T1@1239|Firmicutes,4HDYC@91061|Bacilli,1ZDHN@1386|Bacillus 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10 k141_1028_1 1042377.AFPJ01000057_gene4 4.57e-65 207.0 COG2091@1|root,COG2091@2|Bacteria,1R9EK@1224|Proteobacteria,1S0UM@1236|Gammaproteobacteria,46BMD@72275|Alteromonadaceae 1236|Gammaproteobacteria H Belongs to the P-Pant transferase superfamily - - - ko:K06133 ko00770,map00770 - R01625 RC00002 ko00000,ko00001,ko01000 - - - ACPS k141_5752_2 754476.Q7A_1982 1.31e-65 213.0 COG0300@1|root,COG0300@2|Bacteria,1RAFB@1224|Proteobacteria,1S2HE@1236|Gammaproteobacteria,462BV@72273|Thiotrichales 72273|Thiotrichales S KR domain - - - - - - - - - - - - adh_short k141_5752_3 1395571.TMS3_0118830 1.03e-54 181.0 COG3063@1|root,COG3063@2|Bacteria,1RD9T@1224|Proteobacteria,1S3R3@1236|Gammaproteobacteria 1236|Gammaproteobacteria NU COG0457 FOG TPR repeat - - - - - - - - - - - - TPR_19,TPR_2,TPR_8 k141_12927_1 1453501.JELR01000002_gene511 3.01e-87 271.0 COG2133@1|root,COG2133@2|Bacteria,1MVK5@1224|Proteobacteria,1RPE8@1236|Gammaproteobacteria,4665U@72275|Alteromonadaceae 1236|Gammaproteobacteria G COG2133 Glucose sorbosone dehydrogenases - - - - - - - - - - - - GSDH k141_34204_1 218284.CCDN010000008_gene4159 2.08e-55 176.0 COG0494@1|root,COG0494@2|Bacteria,1VD7F@1239|Firmicutes,4HKEZ@91061|Bacilli,1ZQSR@1386|Bacillus 91061|Bacilli L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - - NUDIX k141_29376_1 218284.CCDN010000005_gene3459 2.19e-43 150.0 COG1168@1|root,COG1168@2|Bacteria,1TP5G@1239|Firmicutes,4H9PE@91061|Bacilli,1ZCQC@1386|Bacillus 91061|Bacilli E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities patB - 4.4.1.8 ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 - R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 k141_11758_1 218284.CCDN010000001_gene475 4.21e-33 117.0 2DR65@1|root,33ACC@2|Bacteria,1VKTW@1239|Firmicutes,4HRJJ@91061|Bacilli,1ZKBY@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_11758_2 1408303.JNJJ01000098_gene600 2.35e-25 96.3 COG0406@1|root,COG0406@2|Bacteria 2|Bacteria G alpha-ribazole phosphatase activity - - - - - - - - - - - - His_Phos_1 k141_6998_1 1294265.JCM21738_105 1.55e-34 118.0 2EJSH@1|root,33DH6@2|Bacteria,1VMUI@1239|Firmicutes,4HS5M@91061|Bacilli,1ZJ2B@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2768) yphE - - - - - - - - - - - DUF2768 k141_26026_1 755731.Clo1100_0591 9.58e-79 249.0 COG0161@1|root,COG0161@2|Bacteria,1TP9N@1239|Firmicutes,25E7B@186801|Clostridia,36W8D@31979|Clostridiaceae 186801|Clostridia H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor bioA - 2.6.1.113,2.6.1.55,2.6.1.62,2.6.1.77 ko:K00833,ko:K03851,ko:K12256,ko:K15372 ko00330,ko00410,ko00430,ko00780,ko01100,map00330,map00410,map00430,map00780,map01100 M00123,M00573,M00577 R00908,R01684,R03231,R05652,R08714 RC00006,RC00008,RC00062,RC00887 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 k141_9390_2 710687.KI912270_gene2871 4.02e-113 340.0 COG1757@1|root,COG1757@2|Bacteria,2I8CQ@201174|Actinobacteria,23CQP@1762|Mycobacteriaceae 201174|Actinobacteria C Na+/H+ antiporter family nhaC - - ko:K03315 - - - - ko00000,ko02000 2.A.35 - - Na_H_antiporter k141_30379_1 1453501.JELR01000005_gene1622 3.31e-89 265.0 COG1376@1|root,COG1376@2|Bacteria,1Q823@1224|Proteobacteria,1S0YT@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Pfam L,D-transpeptidase catalytic domain - - - - - - - - - - - - YkuD k141_36377_1 218284.CCDN010000001_gene1685 1.84e-120 372.0 COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,4HC3Y@91061|Bacilli,1ZCCY@1386|Bacillus 91061|Bacilli V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family yerP1 - - - - - - - - - - - ACR_tran k141_23736_1 1453501.JELR01000001_gene3022 3.13e-36 136.0 COG0443@1|root,COG0443@2|Bacteria,1MVQI@1224|Proteobacteria,1RN74@1236|Gammaproteobacteria,464TI@72275|Alteromonadaceae 1236|Gammaproteobacteria O Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB hscA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0010467,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0050896,GO:0051604,GO:0051716,GO:0070417,GO:0071704,GO:0097159,GO:0097367,GO:0097428,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1990230,GO:1990234 - ko:K04044 - - - - ko00000,ko03110 1.A.33 - - HSP70 k141_23736_2 1453501.JELR01000001_gene3023 5.51e-74 226.0 COG1076@1|root,COG1076@2|Bacteria,1RHZX@1224|Proteobacteria,1S9YH@1236|Gammaproteobacteria,4680Q@72275|Alteromonadaceae 1236|Gammaproteobacteria O Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA hscB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051604,GO:0071704,GO:0097428,GO:1901564,GO:1902494,GO:1990230,GO:1990234 - ko:K04082 - - - - ko00000,ko03029,ko03110 - - - DnaJ,HSCB_C k141_26027_1 237727.NAP1_01740 1.85e-68 229.0 COG1629@1|root,COG4771@2|Bacteria,1MWKN@1224|Proteobacteria,2U10R@28211|Alphaproteobacteria,2K0G1@204457|Sphingomonadales 204457|Sphingomonadales P receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_12928_1 866895.HBHAL_5155 2.28e-98 308.0 COG4412@1|root,COG4412@2|Bacteria,1TQYP@1239|Firmicutes,4HD82@91061|Bacilli,3NG7U@45667|Halobacillus 91061|Bacilli S Immune inhibitor A peptidase M6 - - - ko:K09607 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M6 k141_32906_1 582402.Hbal_3178 1.81e-20 97.4 COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,2TSGE@28211|Alphaproteobacteria,43ZW1@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Sulfotransferase domain - - - - - - - - - - - - Sulfotransfer_3,TPR_16,TPR_19,TPR_2,TPR_8 k141_35476_1 1279017.AQYJ01000027_gene1669 1.35e-118 357.0 COG0515@1|root,COG0631@1|root,COG0515@2|Bacteria,COG0631@2|Bacteria,1MV1P@1224|Proteobacteria,1RNQN@1236|Gammaproteobacteria,464NH@72275|Alteromonadaceae 1236|Gammaproteobacteria T Serine threonine protein - - 3.1.3.16 ko:K01090 - - - - ko00000,ko01000 - - - PP2C_2,Pkinase k141_35476_2 1279017.AQYJ01000027_gene1668 0.0 884.0 COG2223@1|root,COG2223@2|Bacteria,1MU27@1224|Proteobacteria,1RP5H@1236|Gammaproteobacteria,4651E@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG2223 Nitrate nitrite transporter - - - ko:K02575 ko00910,map00910 M00615 - - ko00000,ko00001,ko00002,ko02000 2.A.1.8 - - MFS_1 k141_15102_2 309807.SRU_0883 2.89e-91 295.0 COG0457@1|root,COG0457@2|Bacteria,4NFMI@976|Bacteroidetes,1FK5M@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes S Tetratricopeptide repeat - - - - - - - - - - - - TPR_8 k141_37612_1 1158609.I586_01135 8.38e-15 80.5 COG0438@1|root,COG0438@2|Bacteria,1UNUF@1239|Firmicutes,4IUPW@91061|Bacilli,4B1H7@81852|Enterococcaceae 91061|Bacilli M transferase activity, transferring glycosyl groups - - - - - - - - - - - - - k141_37612_3 754436.JCM19237_3995 2.14e-108 314.0 COG1898@1|root,COG1898@2|Bacteria,1R9YD@1224|Proteobacteria,1S245@1236|Gammaproteobacteria,1XSKQ@135623|Vibrionales 135623|Vibrionales G Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose rfbC - 5.1.3.13 ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R06514 RC01531 ko00000,ko00001,ko00002,ko01000 - - - dTDP_sugar_isom k141_37612_4 1187848.AJYQ01000004_gene160 2.25e-39 139.0 COG1091@1|root,COG1091@2|Bacteria,1MUXM@1224|Proteobacteria,1RSNR@1236|Gammaproteobacteria,1XV68@135623|Vibrionales 135623|Vibrionales M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose rmlD - 1.1.1.133 ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777 RC00182 ko00000,ko00001,ko00002,ko01000 - - - RmlD_sub_bind k141_10472_1 1347086.CCBA010000027_gene3333 6.21e-43 147.0 COG1028@1|root,COG1028@2|Bacteria,1TP3G@1239|Firmicutes,4HACT@91061|Bacilli,1ZDEW@1386|Bacillus 91061|Bacilli IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate - - 1.1.1.30 ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 M00088 R01361 RC00117 ko00000,ko00001,ko00002,ko01000 - - - adh_short_C2 k141_10472_2 218284.CCDN010000008_gene4183 4.78e-133 388.0 COG2610@1|root,COG2610@2|Bacteria,1TQJ6@1239|Firmicutes,4HA01@91061|Bacilli,1ZCGI@1386|Bacillus 91061|Bacilli EG COG2610 H gluconate symporter and related permeases - - - - - - - - - - - - CitMHS,GntP_permease k141_28317_1 218284.CCDN010000001_gene1597 6.88e-41 144.0 COG1916@1|root,COG1916@2|Bacteria,1TSWJ@1239|Firmicutes,4HANT@91061|Bacilli,1ZC3N@1386|Bacillus 91061|Bacilli S TraB family traB - - - - - - - - - - - TraB k141_28317_3 218284.CCDN010000001_gene1596 2.36e-92 273.0 COG0406@1|root,COG0406@2|Bacteria,1UUTV@1239|Firmicutes,4IKAS@91061|Bacilli,1ZG87@1386|Bacillus 91061|Bacilli G Phosphoglycerate mutase family - - - - - - - - - - - - His_Phos_1 k141_17779_1 218284.CCDN010000004_gene3115 1.46e-30 115.0 COG0084@1|root,COG0084@2|Bacteria,1TQUP@1239|Firmicutes,4HBEN@91061|Bacilli,1ZCD5@1386|Bacillus 91061|Bacilli L TatD related DNase M1-591 - - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase k141_17779_2 218284.CCDN010000004_gene3114 1.96e-128 368.0 COG1116@1|root,COG1116@2|Bacteria,1TSW5@1239|Firmicutes,4HAFM@91061|Bacilli,1ZDWC@1386|Bacillus 91061|Bacilli P ABC transporter, ATP-binding protein M1-592 - - - - - - - - - - - ABC_tran k141_33197_1 1453501.JELR01000001_gene1866 1.47e-82 260.0 COG0642@1|root,COG2205@2|Bacteria,1QTVU@1224|Proteobacteria,1RPFY@1236|Gammaproteobacteria,4653U@72275|Alteromonadaceae 1236|Gammaproteobacteria T Signal transduction histidine kinase phoQ GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010350,GO:0016020,GO:0016021,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0031224,GO:0031226,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0035556,GO:0036211,GO:0042578,GO:0042594,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046777,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071496,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.7.13.3 ko:K07637 ko01503,ko02020,map01503,map02020 M00444,M00709,M00721,M00723,M00724,M00744 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 - - - HATPase_c,HisKA,PhoQ_Sensor k141_33197_4 1453501.JELR01000001_gene1863 1.36e-22 93.2 COG3134@1|root,COG3134@2|Bacteria,1MVWD@1224|Proteobacteria,1RQR9@1236|Gammaproteobacteria,468W9@72275|Alteromonadaceae 1236|Gammaproteobacteria S Glycine zipper 2TM domain - - - - - - - - - - - - Rick_17kDa_Anti k141_37896_1 1280001.BAOA01000047_gene1743 4.65e-23 92.4 COG3102@1|root,COG3102@2|Bacteria,1RB98@1224|Proteobacteria,1SI78@1236|Gammaproteobacteria,1XUTF@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria - - - ko:K09907 - - - - ko00000 - - - YecM k141_37896_2 1116375.VEJY3_03935 4.15e-193 536.0 COG0788@1|root,COG0788@2|Bacteria,1MVCF@1224|Proteobacteria,1RN6Q@1236|Gammaproteobacteria,1XSK8@135623|Vibrionales 135623|Vibrionales F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) purU - 3.5.1.10 ko:K01433 ko00630,ko00670,map00630,map00670 - R00944 RC00026,RC00111 ko00000,ko00001,ko01000 - - - ACT,Formyl_trans_N k141_37896_3 1116375.VEJY3_03940 3.06e-238 668.0 COG1199@1|root,COG1199@2|Bacteria,1MVCU@1224|Proteobacteria,1RMNX@1236|Gammaproteobacteria,1XSPF@135623|Vibrionales 135623|Vibrionales KL ATP-dependent helicase yoaA - 3.6.4.12 ko:K03722 - - - - ko00000,ko01000,ko03400 - - - DEAD,DEAD_2,Helicase_C_2,ResIII k141_21274_2 1279017.AQYJ01000028_gene2141 2.34e-147 420.0 COG3248@1|root,COG3248@2|Bacteria,1RC26@1224|Proteobacteria,1S3EM@1236|Gammaproteobacteria,46DI2@72275|Alteromonadaceae 1236|Gammaproteobacteria M Nucleoside-specific channel-forming protein, Tsx - - - - - - - - - - - - Channel_Tsx,DUF5020 k141_21274_3 1042377.AFPJ01000053_gene1498 4.52e-92 276.0 COG0625@1|root,COG0625@2|Bacteria,1N8XH@1224|Proteobacteria,1SJPR@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Glutathione S-Transferase - - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C_3 k141_21274_4 1268635.Loa_02179 1.56e-116 352.0 COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,1RMKV@1236|Gammaproteobacteria,1JCKR@118969|Legionellales 118969|Legionellales E Amino acid permease - - - - - - - - - - - - AA_permease_2 k141_21274_6 626887.J057_15245 2.12e-22 90.5 2BY4C@1|root,32XUX@2|Bacteria,1N0C0@1224|Proteobacteria,1SAJV@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_16586_1 1279017.AQYJ01000028_gene2079 8.47e-219 629.0 COG2755@1|root,COG2755@2|Bacteria,1MXTS@1224|Proteobacteria,1RTPH@1236|Gammaproteobacteria,46419@72275|Alteromonadaceae 1236|Gammaproteobacteria E Concanavalin A-like lectin/glucanases superfamily - - - - - - - - - - - - Laminin_G_3 k141_30590_1 1042377.AFPJ01000052_gene1581 2.17e-23 97.4 COG3712@1|root,COG3712@2|Bacteria,1MZCK@1224|Proteobacteria,1S88I@1236|Gammaproteobacteria,467V5@72275|Alteromonadaceae 1236|Gammaproteobacteria PT Domain of unknown function (DUF4880) - - - ko:K07165 - - - - ko00000 - - - DUF4880,DUF4974,FecR k141_33198_2 218284.CCDN010000004_gene3111 9.83e-20 88.6 COG0715@1|root,COG0715@2|Bacteria,1TPAD@1239|Firmicutes,4HBR9@91061|Bacilli,1ZCIY@1386|Bacillus 91061|Bacilli P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components M1-596 - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1 k141_28319_1 1268072.PSAB_19435 2.36e-109 320.0 COG1028@1|root,COG1028@2|Bacteria,1U2GS@1239|Firmicutes,4H9R9@91061|Bacilli,26QGX@186822|Paenibacillaceae 91061|Bacilli IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short k141_21275_1 42565.FP66_09430 2.58e-23 97.8 COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,1RN6K@1236|Gammaproteobacteria,1XHJR@135619|Oceanospirillales 135619|Oceanospirillales C Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) aceE - 1.2.4.1 ko:K00163 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - Transketolase_N k141_3490_1 218284.CCDN010000007_gene3836 1.02e-127 380.0 COG1113@1|root,COG1113@2|Bacteria,1TP97@1239|Firmicutes,4H9QX@91061|Bacilli,1ZAQB@1386|Bacillus 91061|Bacilli E COG1113 Gamma-aminobutyrate permease and related permeases aapA - - ko:K03293,ko:K11737 - - - - ko00000,ko02000 2.A.3.1,2.A.3.1.7 - - AA_permease k141_2269_1 218284.CCDN010000001_gene632 1.63e-97 297.0 COG1530@1|root,COG1530@2|Bacteria,1TQS4@1239|Firmicutes,4HC3Q@91061|Bacilli,1ZCCF@1386|Bacillus 91061|Bacilli J ribonuclease, Rne Rng family rng - - ko:K08301 - - - - ko00000,ko01000,ko03009,ko03019 - - - RNase_E_G,S1 k141_4668_1 1279017.AQYJ01000021_gene2850 6.01e-181 538.0 COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,1RP0K@1236|Gammaproteobacteria,464YY@72275|Alteromonadaceae 1236|Gammaproteobacteria L DNA polymerase III alpha subunit dnaE GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon k141_4668_2 1042377.AFPJ01000021_gene2131 5.95e-26 97.8 COG3313@1|root,COG3313@2|Bacteria,1NGD5@1224|Proteobacteria,1SGHW@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Fe-S protein - - - ko:K06938 - - - - ko00000 - - - DUF1289 k141_17783_1 1403313.AXBR01000006_gene102 3.6e-63 198.0 COG0262@1|root,COG0262@2|Bacteria,1VB80@1239|Firmicutes,4HIGJ@91061|Bacilli,1ZG71@1386|Bacillus 91061|Bacilli H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis dfrA - 1.5.1.3 ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 M00126,M00840 R00936,R00937,R00939,R00940,R02235,R02236,R11765 RC00109,RC00110,RC00158 ko00000,ko00001,ko00002,ko01000 - - - DHFR_1 k141_33199_1 1121090.KB894686_gene2944 9.83e-15 79.0 COG0860@1|root,COG3807@1|root,COG0860@2|Bacteria,COG3807@2|Bacteria,1UYPW@1239|Firmicutes,4HBVT@91061|Bacilli,1ZDI1@1386|Bacillus 91061|Bacilli M COG3103 SH3 domain protein lytH GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - Amidase_3,SH3_3 k141_30591_1 1340434.AXVA01000014_gene586 5.86e-51 163.0 2C8IW@1|root,32PGC@2|Bacteria,1VADG@1239|Firmicutes,4HNM3@91061|Bacilli,1ZH1I@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF1811) yfhH - - - - - - - - - - - DUF1811 k141_15281_2 223926.28805286 1.37e-99 292.0 COG3054@1|root,COG3054@2|Bacteria,1REC3@1224|Proteobacteria,1S3X5@1236|Gammaproteobacteria,1XSVB@135623|Vibrionales 135623|Vibrionales S Transcriptional regulator ytfJ - - ko:K07109 - - - - ko00000 - - - YtfJ_HI0045 k141_15281_4 1280001.BAOA01000021_gene794 8.66e-83 254.0 COG0803@1|root,COG0803@2|Bacteria,1QUFM@1224|Proteobacteria,1T1XA@1236|Gammaproteobacteria,1XX4X@135623|Vibrionales 135623|Vibrionales P Protein of unknown function (DUF2796) - - - - - - - - - - - - DUF2796 k141_15281_5 1280001.BAOA01000021_gene793 4.49e-150 424.0 COG1136@1|root,COG1136@2|Bacteria,1RA1K@1224|Proteobacteria,1S275@1236|Gammaproteobacteria,1XUZ7@135623|Vibrionales 135623|Vibrionales V COG1136 ABC-type antimicrobial peptide transport system, ATPase component - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_15281_6 1280001.BAOA01000021_gene792 2.6e-279 766.0 COG0577@1|root,COG0577@2|Bacteria,1MVN1@1224|Proteobacteria,1RNVN@1236|Gammaproteobacteria,1XU5T@135623|Vibrionales 135623|Vibrionales V ABC-type antimicrobial peptide transport system, permease component - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD k141_33249_1 218284.CCDN010000001_gene6 2.4e-184 530.0 COG0550@1|root,COG0550@2|Bacteria,1TPUS@1239|Firmicutes,4HA6C@91061|Bacilli,1ZB7D@1386|Bacillus 91061|Bacilli L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topA - 5.99.1.2 ko:K03168 - - - - ko00000,ko01000,ko03032,ko03400 - - - Topoisom_bac,Toprim,zf-C4_Topoisom k141_17822_1 1294265.JCM21738_1767 5.08e-97 287.0 COG0095@1|root,COG0095@2|Bacteria,1TQKA@1239|Firmicutes,4HCPS@91061|Bacilli,1ZCIA@1386|Bacillus 91061|Bacilli H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes lipL GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.3.1.200,2.3.1.204 ko:K16869,ko:K18821 - - - - ko00000,ko01000 - - - BPL_LplA_LipB k141_2324_1 218284.CCDN010000001_gene1513 1.34e-76 254.0 COG1112@1|root,COG1112@2|Bacteria,1UNF1@1239|Firmicutes,4IPKF@91061|Bacilli,1ZDR8@1386|Bacillus 91061|Bacilli L COG1112 Superfamily I DNA and RNA helicases and helicase subunits - - - - - - - - - - - - AAA_11,AAA_12 k141_37950_1 1042377.AFPJ01000035_gene2624 9.14e-13 67.0 COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,1RSKJ@1236|Gammaproteobacteria,46CN9@72275|Alteromonadaceae 1236|Gammaproteobacteria EH Amino-transferase class IV ilvE - 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_4 k141_37950_2 1453501.JELR01000001_gene3233 1.1e-127 364.0 28H8Z@1|root,2Z7KS@2|Bacteria,1MW9T@1224|Proteobacteria,1RQV1@1236|Gammaproteobacteria,465P3@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF1282) - - - - - - - - - - - - DUF1282 k141_30620_2 218284.CCDN010000002_gene2556 4.2e-37 127.0 COG1051@1|root,COG1051@2|Bacteria,1VIBR@1239|Firmicutes,4HQDQ@91061|Bacilli,1ZHJQ@1386|Bacillus 91061|Bacilli F NIPSNAP - - - - - - - - - - - - NIPSNAP k141_4712_1 218284.CCDN010000005_gene3334 3.53e-249 702.0 COG0209@1|root,COG0209@2|Bacteria,1TPFH@1239|Firmicutes,4H9X0@91061|Bacilli,1ZANT@1386|Bacillus 91061|Bacilli F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdA - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN k141_28375_1 1042377.AFPJ01000007_gene1869 2.67e-39 142.0 COG5621@1|root,COG5621@2|Bacteria,1MUVF@1224|Proteobacteria,1RZ65@1236|Gammaproteobacteria,466MJ@72275|Alteromonadaceae 1236|Gammaproteobacteria S secreted hydrolase attH - - - - - - - - - - - CrtC,Lipocalin_9 k141_28375_2 1042377.AFPJ01000007_gene1870 4.32e-185 542.0 COG3127@1|root,COG3127@2|Bacteria,1QXGA@1224|Proteobacteria,1T3BG@1236|Gammaproteobacteria,467CX@72275|Alteromonadaceae 1236|Gammaproteobacteria Q COG0577 ABC-type antimicrobial peptide transport system, permease component - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX k141_36626_1 981383.AEWH01000068_gene372 2.68e-30 115.0 COG1484@1|root,COG1484@2|Bacteria,1TPZX@1239|Firmicutes,4HABS@91061|Bacilli 91061|Bacilli L Primosomal protein DnaI dnaI GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - ko:K11144 - - - - ko00000,ko03032 - - - DnaI_N,IstB_IS21 k141_33252_1 1294265.JCM21738_3638 5.08e-99 303.0 COG0840@1|root,COG0840@2|Bacteria,1V0SD@1239|Firmicutes,4HD8P@91061|Bacilli,1ZCT0@1386|Bacillus 91061|Bacilli NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - MCPsignal k141_2326_2 1347086.CCBA010000028_gene3660 1.94e-82 256.0 COG2270@1|root,COG2270@2|Bacteria,1TRTH@1239|Firmicutes,4H9VB@91061|Bacilli,1ZDX4@1386|Bacillus 91061|Bacilli S COG2270 Permeases of the major facilitator superfamily yxiO - - ko:K06902 ko04138,map04138 - - - ko00000,ko00001,ko02000,ko04131 2.A.1.24,9.A.15.1 - - ATG22 k141_3505_1 388413.ALPR1_03615 2.31e-139 404.0 COG2370@1|root,COG2370@2|Bacteria,4NTCZ@976|Bacteroidetes,47VDK@768503|Cytophagia 976|Bacteroidetes O HupE / UreJ protein - - - - - - - - - - - - HupE_UreJ_2 k141_3505_2 388413.ALPR1_03620 4.13e-32 123.0 COG0760@1|root,COG0760@2|Bacteria 2|Bacteria O peptidyl-prolyl cis-trans isomerase activity ppiD - 5.2.1.8 ko:K03770 - - - - ko00000,ko01000,ko03110 - - - Rotamase_2,SurA_N_3 k141_8155_2 218284.CCDN010000006_gene3585 2.9e-37 135.0 COG0460@1|root,COG0460@2|Bacteria,1TQ2H@1239|Firmicutes,4HBAP@91061|Bacilli,1ZCGH@1386|Bacillus 91061|Bacilli E homoserine dehydrogenase - - 1.1.1.3 ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00017,M00018 R01773,R01775 RC00087 ko00000,ko00001,ko00002,ko01000 - - - Homoserine_dh,NAD_binding_3 k141_37951_1 1408254.T458_09380 1.4e-54 188.0 COG0209@1|root,COG0209@2|Bacteria,1TT3U@1239|Firmicutes,4HFF1@91061|Bacilli,26R3N@186822|Paenibacillaceae 91061|Bacilli F Ribonucleotide reductase, barrel domain - - - - - - - - - - - - Ribonuc_red_lgC k141_30621_1 1294265.JCM21738_4607 1.94e-168 476.0 COG1623@1|root,COG1623@2|Bacteria,1TQD8@1239|Firmicutes,4HAQP@91061|Bacilli,1ZBIY@1386|Bacillus 91061|Bacilli L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation disA - 2.7.7.85 ko:K07067 - - - - ko00000,ko01000 - - - DisA-linker,DisA_N,HHH,HHH_2 k141_36627_1 218284.CCDN010000002_gene2762 1.37e-121 351.0 COG0300@1|root,COG0300@2|Bacteria,1TPN1@1239|Firmicutes,4HBGE@91061|Bacilli,1ZDT2@1386|Bacillus 91061|Bacilli S Enoyl-(Acyl carrier protein) reductase - - - - - - - - - - - - adh_short k141_2327_1 1294265.JCM21738_2918 3.17e-123 356.0 COG0561@1|root,COG0561@2|Bacteria,1V2XI@1239|Firmicutes,4HG2U@91061|Bacilli,1ZB1F@1386|Bacillus 91061|Bacilli S hydrolases of the HAD superfamily yhaX - - - - - - - - - - - Hydrolase_3 k141_33253_2 1307436.PBF_13039 1.51e-13 69.7 COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,4H9VR@91061|Bacilli,1ZB1D@1386|Bacillus 91061|Bacilli E Acetolactate synthase ilvB - 2.2.1.6 ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 M00019,M00570,M00582 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - iYO844.BSU28310 TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N k141_3506_1 472759.Nhal_2573 4.02e-82 259.0 COG4783@1|root,COG4783@2|Bacteria,1QUMJ@1224|Proteobacteria,1T2RP@1236|Gammaproteobacteria,1WZYU@135613|Chromatiales 135613|Chromatiales S peptidase M48, Ste24p - - - - - - - - - - - - Peptidase_M48,TPR_16 k141_8156_1 218284.CCDN010000002_gene2669 2.39e-31 114.0 COG0454@1|root,COG0456@2|Bacteria,1V1MF@1239|Firmicutes,4HGE9@91061|Bacilli,1ZFUH@1386|Bacillus 91061|Bacilli K Acetyltransferase (GNAT) family - - - - - - - - - - - - Acetyltransf_1 k141_8156_2 1002809.SSIL_2280 1.31e-22 87.8 2ENQT@1|root,33GC0@2|Bacteria,1VM6Q@1239|Firmicutes,4HS11@91061|Bacilli,26GG9@186818|Planococcaceae 91061|Bacilli S Fe3 hydroxamate ABC transporter substrate-binding protein - - - - - - - - - - - - - k141_8156_3 1385511.N783_15860 2.27e-13 69.7 COG3356@1|root,COG3356@2|Bacteria,1V42W@1239|Firmicutes,4HK1K@91061|Bacilli 91061|Bacilli S Neutral/alkaline non-lysosomal ceramidase, N-terminal - - - - - - - - - - - - Ceramidase_alk k141_21332_1 1348635.BBJY01000003_gene3768 1.79e-246 681.0 2DB8U@1|root,2Z7SW@2|Bacteria,1NQRP@1224|Proteobacteria,1RS94@1236|Gammaproteobacteria,1XXEG@135623|Vibrionales 135623|Vibrionales G Alginate lyase - - - - - - - - - - - - Alginate_lyase k141_21332_2 1348635.BBJY01000003_gene3767 5.24e-206 582.0 COG0591@1|root,COG0591@2|Bacteria,1MW6E@1224|Proteobacteria,1RXYK@1236|Gammaproteobacteria,1XSDY@135623|Vibrionales 135623|Vibrionales E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - - - - - - - - - - SSF k141_3507_1 926569.ANT_08160 2.73e-23 100.0 COG0842@1|root,COG0842@2|Bacteria,2G774@200795|Chloroflexi 200795|Chloroflexi V PFAM ABC-2 type transporter - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 k141_31749_1 1279017.AQYJ01000028_gene2021 6.53e-163 464.0 COG0451@1|root,COG0451@2|Bacteria,1RKZT@1224|Proteobacteria,1S4B4@1236|Gammaproteobacteria,468WR@72275|Alteromonadaceae 1236|Gammaproteobacteria M NmrA-like family - - 1.1.1.219 ko:K00091 - - - - ko00000,ko01000 - - - Abhydrolase_6,Epimerase,NAD_binding_4 k141_31749_6 1453501.JELR01000002_gene1276 0.0 920.0 COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,1RMT7@1236|Gammaproteobacteria,469B8@72275|Alteromonadaceae 1236|Gammaproteobacteria S Bacterial protein of unknown function (DUF885) - - - - - - - - - - - - DUF885 k141_31749_7 1042377.AFPJ01000028_gene2222 6.84e-178 506.0 COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,1RNGN@1236|Gammaproteobacteria,464U6@72275|Alteromonadaceae 1236|Gammaproteobacteria G COG2133 Glucose sorbosone dehydrogenases - - - ko:K21430 - - - - ko00000,ko01000 - - - Cytochrome_CBB3,GSDH k141_31749_8 714943.Mucpa_3931 6.32e-72 223.0 COG3548@1|root,COG3548@2|Bacteria,4NPIF@976|Bacteroidetes,1IS6F@117747|Sphingobacteriia 976|Bacteroidetes S integral membrane protein - - - - - - - - - - - - DUF1211 k141_31749_9 1279017.AQYJ01000028_gene2026 7.94e-114 333.0 2CHNQ@1|root,2Z7KM@2|Bacteria,1REIJ@1224|Proteobacteria,1S870@1236|Gammaproteobacteria,46BQ7@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_31749_10 1215092.PA6_028_01190 9.98e-83 254.0 COG1814@1|root,COG1814@2|Bacteria,1MUZE@1224|Proteobacteria,1S2G7@1236|Gammaproteobacteria,1YH76@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S VIT family - - - - - - - - - - - - VIT1 k141_31749_11 1042377.AFPJ01000028_gene2214 1.15e-116 341.0 COG3637@1|root,COG3637@2|Bacteria,1N2XM@1224|Proteobacteria,1SIDP@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Outer membrane protein beta-barrel domain - - - - - - - - - - - - OMP_b-brl k141_31749_13 1453501.JELR01000002_gene1279 5.67e-171 487.0 COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,1RRTP@1236|Gammaproteobacteria,464NN@72275|Alteromonadaceae 1236|Gammaproteobacteria T GGDEF domain - GO:0003674,GO:0003824,GO:0005488,GO:0008144,GO:0016740,GO:0016772,GO:0016779,GO:0019825,GO:0020037,GO:0036094,GO:0042165,GO:0043167,GO:0043169,GO:0046906,GO:0048037,GO:0052621,GO:0070025,GO:0097159,GO:1901363 2.7.7.65 ko:K13069 - - R08057 - ko00000,ko01000 - - - GGDEF k141_31749_14 1279017.AQYJ01000028_gene2029 1.69e-79 240.0 COG2110@1|root,COG2110@2|Bacteria,1NQ72@1224|Proteobacteria,1SPIK@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Macro domain - - - - - - - - - - - - Macro k141_31749_15 1279017.AQYJ01000028_gene2032 0.0 1114.0 COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,1RMJB@1236|Gammaproteobacteria,46493@72275|Alteromonadaceae 1236|Gammaproteobacteria T membrane GTPase involved in stress response typA GO:0000027,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006996,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071826,GO:0071840 - ko:K06207 - - - - ko00000 - - - EFG_C,GTP_EFTU,GTP_EFTU_D2 k141_31749_16 399739.Pmen_0219 1.91e-29 125.0 COG2866@1|root,COG2866@2|Bacteria,1N6CX@1224|Proteobacteria,1RZAW@1236|Gammaproteobacteria,1YFQT@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria E Protein of unknown function (DUF2817) - - - - - - - - - - - - DUF2817 k141_31749_17 1042377.AFPJ01000028_gene2207 1.35e-174 499.0 COG5002@1|root,COG5002@2|Bacteria,1NWB7@1224|Proteobacteria,1SPHN@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Sensory histidine kinase in two-component regulatory system with RstA - - 2.7.13.3 ko:K02484,ko:K07639,ko:K18143 ko01501,ko02020,map01501,map02020 M00446,M00649,M00655 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 - - - HATPase_c,HisKA k141_31749_18 1042377.AFPJ01000028_gene2206 4e-111 326.0 COG0745@1|root,COG0745@2|Bacteria,1MYNB@1224|Proteobacteria,1S77Z@1236|Gammaproteobacteria,46AXP@72275|Alteromonadaceae 1236|Gammaproteobacteria T Transcriptional regulatory protein, C terminal - - - - - - - - - - - - Response_reg,Trans_reg_C k141_31749_20 1042377.AFPJ01000028_gene2204 6.44e-110 326.0 COG3713@1|root,COG3713@2|Bacteria,1N3RD@1224|Proteobacteria,1SAIX@1236|Gammaproteobacteria,468UZ@72275|Alteromonadaceae 1236|Gammaproteobacteria M MltA-interacting protein MipA - - - ko:K07274 - - - - ko00000,ko02000 9.B.99.1 - - MipA k141_31749_22 1279017.AQYJ01000028_gene2034 4.34e-315 863.0 COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,1RMD1@1236|Gammaproteobacteria,464KQ@72275|Alteromonadaceae 1236|Gammaproteobacteria E glutamine synthetase glnA - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - iJN746.PP_5046 Gln-synt_C,Gln-synt_N k141_31749_23 1279017.AQYJ01000028_gene2035 1.59e-61 200.0 2AFX8@1|root,3160N@2|Bacteria,1QE3Z@1224|Proteobacteria,1TAFT@1236|Gammaproteobacteria,4691A@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF4124) - - - - - - - - - - - - DUF4124 k141_31749_26 517417.Cpar_1700 3.13e-238 665.0 COG3004@1|root,COG3004@2|Bacteria,1FDWE@1090|Chlorobi 1090|Chlorobi P ) H( ) antiporter that extrudes sodium in exchange for external protons nhaA - - ko:K03313 - - - - ko00000,ko02000 2.A.33.1 - - Na_H_antiport_1 k141_31749_27 1537994.JQFW01000002_gene3490 1.03e-11 73.6 2E2VX@1|root,32XXD@2|Bacteria,1N2KJ@1224|Proteobacteria,1S8V8@1236|Gammaproteobacteria,4686Y@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_4716_1 1279017.AQYJ01000025_gene716 4.31e-50 163.0 2FGZH@1|root,348UM@2|Bacteria,1P152@1224|Proteobacteria,1SRIV@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_2329_1 89187.ISM_03000 1.58e-100 301.0 COG1638@1|root,COG1638@2|Bacteria,1PZF7@1224|Proteobacteria,2TUGS@28211|Alphaproteobacteria 28211|Alphaproteobacteria G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component - - - - - - - - - - - - DctP k141_33254_1 1280001.BAOA01000021_gene715 1.3e-93 276.0 COG3637@1|root,COG3637@2|Bacteria,1NC11@1224|Proteobacteria,1SX0Q@1236|Gammaproteobacteria,1XWCI@135623|Vibrionales 135623|Vibrionales M Outer membrane protein beta-barrel domain - - - - - - - - - - - - OMP_b-brl k141_2330_1 218284.CCDN010000001_gene185 3.29e-24 95.1 28UJ1@1|root,2ZGPN@2|Bacteria,1W48G@1239|Firmicutes,4I25Y@91061|Bacilli,1ZE4R@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3993) - - - - - - - - - - - - DUF3993 k141_28376_2 326442.PSHAa1856 4.18e-276 772.0 COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,1RNB7@1236|Gammaproteobacteria,2Q07D@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria S metal-dependent hydrolase with the TIM-barrel fold - - - - - - - - - - - - Amidohydro_3 k141_36994_1 218284.CCDN010000007_gene3903 7.14e-64 200.0 COG4912@1|root,COG4912@2|Bacteria,1V4WB@1239|Firmicutes,4HFXG@91061|Bacilli,1ZGCX@1386|Bacillus 91061|Bacilli L DNA alkylation repair alkD - - - - - - - - - - - DNA_alkylation k141_27499_2 1042377.AFPJ01000037_gene2990 1.66e-180 506.0 COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,1RP45@1236|Gammaproteobacteria,464EU@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0714 MoxR-like ATPases moxR - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 k141_27499_3 1453501.JELR01000001_gene1844 6.28e-138 401.0 COG1721@1|root,COG1721@2|Bacteria,1R3QD@1224|Proteobacteria,1S5F7@1236|Gammaproteobacteria,466X1@72275|Alteromonadaceae 1236|Gammaproteobacteria S conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - - - - - - - - - - DUF58 k141_27499_4 1279017.AQYJ01000021_gene2904 0.0 912.0 COG1305@1|root,COG1305@2|Bacteria,1MWCE@1224|Proteobacteria,1RPH9@1236|Gammaproteobacteria,464NQ@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG1305 Transglutaminase-like enzymes tgpA - 2.3.2.13 ko:K22452 - - - - ko00000,ko01000 - - - DUF3488,DUF4129,Transglut_core k141_27499_5 1279017.AQYJ01000021_gene2905 4.01e-45 157.0 COG0477@1|root,COG2814@2|Bacteria,1RAYJ@1224|Proteobacteria,1S7XJ@1236|Gammaproteobacteria,46AYE@72275|Alteromonadaceae 1236|Gammaproteobacteria EGP Transmembrane secretion effector - - - - - - - - - - - - MFS_1,MFS_3 k141_16815_1 1117647.M5M_10260 3.96e-91 294.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MUWN@1224|Proteobacteria,1RN1E@1236|Gammaproteobacteria,1J635@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec k141_23931_1 1279017.AQYJ01000029_gene3773 4.68e-69 214.0 COG1399@1|root,COG1399@2|Bacteria,1PGKW@1224|Proteobacteria,1RRK3@1236|Gammaproteobacteria,46873@72275|Alteromonadaceae 1236|Gammaproteobacteria S metal-binding, possibly nucleic acid-binding protein yceD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K07040 - - - - ko00000 - - - DUF177 k141_23931_3 1279017.AQYJ01000029_gene3775 1.14e-176 499.0 COG0416@1|root,COG0416@2|Bacteria,1MVM3@1224|Proteobacteria,1RM7R@1236|Gammaproteobacteria,464HB@72275|Alteromonadaceae 1236|Gammaproteobacteria I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA plsX GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0071704,GO:0090407,GO:1901576 2.3.1.15 ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - iEcDH1_1363.EcDH1_2557,iSFxv_1172.SFxv_1246,iY75_1357.Y75_RS05695 FA_synthesis k141_23931_4 1453501.JELR01000001_gene2223 7.8e-174 490.0 COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,1RNH3@1236|Gammaproteobacteria,464BG@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG0331 (acyl-carrier-protein) S-malonyltransferase fabD GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.39 ko:K00645 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082 R01626,R11671 RC00004,RC00039,RC02727 ko00000,ko00001,ko00002,ko01000,ko01004 - - iEcE24377_1341.EcE24377A_1213,iJN746.PP_1913,iPC815.YPO1598 Acyl_transf_1 k141_18080_2 1408254.T458_13410 5.74e-24 97.1 2C7DI@1|root,34AS9@2|Bacteria,1VFN9@1239|Firmicutes,4HQ3G@91061|Bacilli 91061|Bacilli S TadE-like protein - - - - - - - - - - - - TadE k141_31125_2 1042377.AFPJ01000024_gene781 2.4e-208 578.0 COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,1RP6Z@1236|Gammaproteobacteria,465RB@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family ilvE GO:0003674,GO:0003824,GO:0004084,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006531,GO:0006532,GO:0006551,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009081,GO:0009082,GO:0009098,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - iB21_1397.B21_03597,iECBD_1354.ECBD_4269,iECB_1328.ECB_03648,iECD_1391.ECD_03648,iECO103_1326.ECO103_4394 Aminotran_4 k141_25129_1 218284.CCDN010000007_gene3806 1.3e-62 201.0 COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,4H9SQ@91061|Bacilli,1ZBUI@1386|Bacillus 91061|Bacilli J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner ychF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - ko:K06942 - - - - ko00000,ko03009 - - - MMR_HSR1,YchF-GTPase_C k141_267_1 1042377.AFPJ01000036_gene1151 1.12e-56 182.0 COG4990@1|root,COG4990@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Peptidase_C39_2,Peptidase_C70 k141_267_2 565045.NOR51B_1384 6.42e-45 161.0 2DB6N@1|root,2Z7HZ@2|Bacteria,1PQ9P@1224|Proteobacteria,1RRV9@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF4392) - - - - - - - - - - - - DUF4392 k141_2590_1 260799.BAS0455 4.47e-43 154.0 COG4722@1|root,COG4722@2|Bacteria,1VZIH@1239|Firmicutes,4I8NR@91061|Bacilli,1ZJI2@1386|Bacillus 91061|Bacilli S Phage tail protein - - - - - - - - - - - - Sipho_tail k141_12081_1 218284.CCDN010000006_gene3536 1.27e-174 497.0 COG1785@1|root,COG1785@2|Bacteria,1TQCI@1239|Firmicutes,4HA27@91061|Bacilli,1ZB3J@1386|Bacillus 91061|Bacilli P Belongs to the alkaline phosphatase family phoB - 3.1.3.1 ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 M00126 R02135,R04620 RC00017 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 - - - Alk_phosphatase k141_29871_2 1453501.JELR01000002_gene1507 3.3e-132 377.0 COG0179@1|root,COG0179@2|Bacteria,1MVFA@1224|Proteobacteria,1RN6Y@1236|Gammaproteobacteria,466CE@72275|Alteromonadaceae 1236|Gammaproteobacteria Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) ycgM - - - - - - - - - - - FAA_hydrolase k141_29871_3 1042377.AFPJ01000044_gene640 4.09e-100 293.0 COG0252@1|root,COG0252@2|Bacteria,1RHAW@1224|Proteobacteria,1S5WS@1236|Gammaproteobacteria,467N0@72275|Alteromonadaceae 1236|Gammaproteobacteria EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D VL23_12675 - 3.5.1.1 ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 - R00485 RC00010,RC02798 ko00000,ko00001,ko01000 - - - Asparaginase k141_25130_1 1453501.JELR01000002_gene1224 1.12e-49 172.0 COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,464J7@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0405 Gamma-glutamyltransferase ggt - 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept k141_25130_2 1453501.JELR01000002_gene1222 6.29e-87 259.0 COG1495@1|root,COG1495@2|Bacteria,1RKPG@1224|Proteobacteria,1SC4J@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Disulfide bond formation protein DsbB lidJ - - - - - - - - - - - DsbB k141_31127_1 1283337.B0ZSI1_BPHA1 1.03e-72 225.0 4QBQJ@10239|Viruses,4QVNC@35237|dsDNA viruses no RNA stage,4QPZ3@28883|Caudovirales,4QIN9@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k141_12082_1 218284.CCDN010000001_gene1296 1.75e-97 287.0 COG0494@1|root,COG0494@2|Bacteria,1V6SF@1239|Firmicutes,4HG46@91061|Bacilli,1ZB2X@1386|Bacillus 91061|Bacilli L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes XK27_06885 - - - - - - - - - - - NUDIX k141_10844_1 218284.CCDN010000001_gene190 1.24e-246 697.0 COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,4HA3G@91061|Bacilli,1ZAVY@1386|Bacillus 91061|Bacilli T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,PAS_4,PAS_9 k141_20342_1 94122.Shewana3_1740 6.62e-81 269.0 COG1404@1|root,COG1404@2|Bacteria,1PE57@1224|Proteobacteria,1RWPJ@1236|Gammaproteobacteria,2QE2X@267890|Shewanellaceae 1236|Gammaproteobacteria O Belongs to the peptidase S8 family - - - - - - - - - - - - - k141_3795_2 1042377.AFPJ01000032_gene2714 2.09e-273 752.0 COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,1RNS4@1236|Gammaproteobacteria,4649C@72275|Alteromonadaceae 1236|Gammaproteobacteria F Belongs to the GARS family purD GO:0000166,GO:0003674,GO:0003824,GO:0004637,GO:0005488,GO:0005524,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016874,GO:0016879,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.2.6,6.3.4.13 ko:K01945,ko:K13713 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144,R04591 RC00064,RC00090,RC00162,RC00166 ko00000,ko00001,ko00002,ko01000 - - iECNA114_1301.ECNA114_3417,iECSF_1327.ECSF_3859,iJN746.PP_4823,iPC815.YPO3729 GARS_A,GARS_C,GARS_N k141_3795_3 1453501.JELR01000002_gene1508 1.42e-119 345.0 COG2941@1|root,COG2941@2|Bacteria,1RAA1@1224|Proteobacteria,1RPMV@1236|Gammaproteobacteria,466J9@72275|Alteromonadaceae 1236|Gammaproteobacteria H Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol coq7 - - ko:K06134 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00128 R04984,R08775 RC01254 ko00000,ko00001,ko00002,ko01000 - - - COQ7 k141_3795_4 1042377.AFPJ01000044_gene639 2.66e-77 232.0 COG1765@1|root,COG1765@2|Bacteria,1RCZW@1224|Proteobacteria,1S3XF@1236|Gammaproteobacteria,4672B@72275|Alteromonadaceae 1236|Gammaproteobacteria O redox protein, regulator of disulfide bond formation yhfA - - ko:K07397 - - - - ko00000 - - - OsmC k141_3795_5 1453501.JELR01000002_gene771 2.23e-146 412.0 COG0664@1|root,COG0664@2|Bacteria,1MXID@1224|Proteobacteria,1RMIZ@1236|Gammaproteobacteria,465GT@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases crp GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0007154,GO:0007584,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009605,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0009991,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016070,GO:0017076,GO:0018130,GO:0019001,GO:0019219,GO:0019222,GO:0019438,GO:0030551,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0032553,GO:0032555,GO:0032561,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0035438,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045013,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0045990,GO:0046483,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0061984,GO:0061985,GO:0065007,GO:0070887,GO:0071496,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:0140110,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 - - - ko00000,ko00001,ko03000 - - - Crp,cNMP_binding k141_25131_1 218284.CCDN010000001_gene1336 1.74e-37 133.0 COG0586@1|root,COG0586@2|Bacteria,1V31C@1239|Firmicutes,4HGNQ@91061|Bacilli,1ZICE@1386|Bacillus 91061|Bacilli S SNARE associated Golgi protein - - - ko:K03975 - - - - ko00000 - - - SNARE_assoc k141_31128_1 218284.CCDN010000004_gene3153 2e-63 209.0 COG0189@1|root,COG0189@2|Bacteria,1V1EV@1239|Firmicutes,4HFNI@91061|Bacilli,1ZBM5@1386|Bacillus 91061|Bacilli HJ YheC/D like ATP-grasp - - - - - - - - - - - - ATPgrasp_YheCD k141_18083_1 768671.ThimaDRAFT_1732 3.46e-62 201.0 COG4313@1|root,COG4313@2|Bacteria,1PC95@1224|Proteobacteria,1RZJZ@1236|Gammaproteobacteria,1WZES@135613|Chromatiales 135613|Chromatiales C Putative MetA-pathway of phenol degradation - - - - - - - - - - - - Phenol_MetA_deg k141_269_1 997346.HMPREF9374_3293 2.31e-32 124.0 COG1024@1|root,COG1024@2|Bacteria,1TQ2V@1239|Firmicutes,4HBT0@91061|Bacilli,27B90@186824|Thermoactinomycetaceae 91061|Bacilli I Enoyl-CoA hydratase/isomerase - - 5.3.3.18 ko:K15866 ko00360,ko01120,map00360,map01120 - R09837,R09839 RC00004,RC00326,RC02689,RC03003 ko00000,ko00001,ko01000 - - - ECH_1 k141_2592_1 1453501.JELR01000002_gene373 1.73e-58 194.0 COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,1RMR2@1236|Gammaproteobacteria,464J6@72275|Alteromonadaceae 1236|Gammaproteobacteria G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate glmM - 5.4.2.10 ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 - R02060 RC00408 ko00000,ko00001,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV k141_2592_2 1279017.AQYJ01000024_gene839 2.34e-21 90.1 COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,1RM8I@1236|Gammaproteobacteria,466HI@72275|Alteromonadaceae 1236|Gammaproteobacteria G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) tpiA GO:0003674,GO:0003824,GO:0004807,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01015 RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 - - iJN746.PP_4715 TIM k141_14473_1 1294265.JCM21738_1860 2.17e-146 413.0 COG0699@1|root,COG0699@2|Bacteria,1UHR6@1239|Firmicutes,4I1K3@91061|Bacilli,1ZS13@1386|Bacillus 91061|Bacilli S chaperone-mediated protein folding - - - - - - - - - - - - Dynamin_N,TPR_8 k141_26390_1 218284.CCDN010000007_gene4017 4.51e-86 268.0 COG4147@1|root,COG4147@2|Bacteria,1UHT5@1239|Firmicutes,4HCF6@91061|Bacilli,1ZCX7@1386|Bacillus 91061|Bacilli S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family ywcA - - ko:K14393 - - - - ko00000,ko02000 2.A.21.7 - - SSF k141_16817_1 1121938.AUDY01000009_gene2364 1.45e-109 334.0 COG2015@1|root,COG2015@2|Bacteria,1TR7Q@1239|Firmicutes,4HIVI@91061|Bacilli 91061|Bacilli Q Alkyl sulfatase dimerisation sepA - - - - - - - - - - - Alkyl_sulf_C,Alkyl_sulf_dimr,Lactamase_B k141_27503_1 42565.FP66_10720 4.85e-112 340.0 COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,1RMYM@1236|Gammaproteobacteria,1XHBT@135619|Oceanospirillales 135619|Oceanospirillales J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation metG - 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1g,tRNA_bind k141_10845_1 218284.CCDN010000007_gene3963 3.27e-175 500.0 COG0504@1|root,COG0504@2|Bacteria,1TP34@1239|Firmicutes,4H9X6@91061|Bacilli,1ZB0S@1386|Bacillus 91061|Bacilli F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates pyrG - 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 - - - CTP_synth_N,GATase k141_9673_12 1116375.VEJY3_18491 4.86e-213 591.0 COG4948@1|root,COG4948@2|Bacteria,1MW76@1224|Proteobacteria,1RMKS@1236|Gammaproteobacteria,1Y07W@135623|Vibrionales 135623|Vibrionales M Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - 5.1.1.20 ko:K19802 - - R10938 RC03309 ko00000,ko01000 - - - MR_MLE_C,MR_MLE_N k141_9673_13 1116375.VEJY3_18486 5.92e-236 650.0 COG3367@1|root,COG3367@2|Bacteria,1MVEX@1224|Proteobacteria,1RNVG@1236|Gammaproteobacteria,1XZYA@135623|Vibrionales 135623|Vibrionales S Domain of unknown function (DUF1611_N) Rossmann-like domain - - - - - - - - - - - - DUF1611,DUF1611_N k141_9673_14 1116375.VEJY3_18481 7.86e-154 434.0 COG4160@1|root,COG4160@2|Bacteria,1QV6B@1224|Proteobacteria,1RNC2@1236|Gammaproteobacteria,1XZV8@135623|Vibrionales 135623|Vibrionales P Binding-protein-dependent transport system inner membrane component - - - ko:K02029 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 k141_9673_15 1116375.VEJY3_18476 8.99e-164 459.0 COG4215@1|root,COG4215@2|Bacteria,1PHCT@1224|Proteobacteria,1T9G3@1236|Gammaproteobacteria,1Y0M2@135623|Vibrionales 135623|Vibrionales P Binding-protein-dependent transport system inner membrane component - - - ko:K02029 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 k141_9673_16 1116375.VEJY3_18471 9.62e-172 481.0 COG0834@1|root,COG0834@2|Bacteria,1MXIA@1224|Proteobacteria,1T9G0@1236|Gammaproteobacteria,1Y037@135623|Vibrionales 135623|Vibrionales ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain - - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 k141_9673_17 1116375.VEJY3_18466 7.44e-227 626.0 COG0583@1|root,COG0583@2|Bacteria,1PMTG@1224|Proteobacteria,1S7MV@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_9673_18 223926.28808689 4.66e-18 75.5 2AWVS@1|root,31NT5@2|Bacteria,1QKHB@1224|Proteobacteria,1TIMG@1236|Gammaproteobacteria,1XZC4@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_9673_19 1219076.N646_4642 8.81e-68 206.0 2AW94@1|root,31N4F@2|Bacteria,1QJVW@1224|Proteobacteria,1THXH@1236|Gammaproteobacteria,1XXTY@135623|Vibrionales 135623|Vibrionales - - VPA0521 - - - - - - - - - - - - k141_9673_20 1116375.VEJY3_22031 4.3e-278 764.0 COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,1MVTF@1224|Proteobacteria,1RM7S@1236|Gammaproteobacteria,1XSZJ@135623|Vibrionales 135623|Vibrionales M COG0739 Membrane proteins related to metalloendopeptidases - - - - - - - - - - - - OapA,Peptidase_M23 k141_9673_21 1116375.VEJY3_22036 3.31e-111 323.0 29W5G@1|root,30HQI@2|Bacteria,1QJKS@1224|Proteobacteria,1THME@1236|Gammaproteobacteria,1XWPV@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_9673_22 223926.28808681 2.11e-80 239.0 COG3791@1|root,COG3791@2|Bacteria,1N023@1224|Proteobacteria,1SAQH@1236|Gammaproteobacteria,1XXDN@135623|Vibrionales 135623|Vibrionales S Glutathione-dependent formaldehyde-activating enzyme - - - - - - - - - - - - GFA k141_9673_23 1116375.VEJY3_22046 9.75e-61 191.0 COG3619@1|root,COG3619@2|Bacteria,1RB5Q@1224|Proteobacteria,1S70A@1236|Gammaproteobacteria,1XU9T@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF1275) - - - - - - - - - - - - DUF1275 k141_33467_2 1285586.H131_11788 1.96e-106 362.0 COG5412@1|root,COG5412@2|Bacteria,1UWZ6@1239|Firmicutes,4I2HJ@91061|Bacilli,3IYXP@400634|Lysinibacillus 91061|Bacilli D Phage-related minor tail protein - - - - - - - - - - - - - k141_1359_1 218284.CCDN010000007_gene3785 1.65e-123 361.0 COG2206@1|root,COG2206@2|Bacteria,1TR95@1239|Firmicutes,4HB8S@91061|Bacilli,1ZCD6@1386|Bacillus 91061|Bacilli T HD domain M1-161 - - - - - - - - - - - HD,HD_5 k141_25167_1 1121090.KB894697_gene2011 1.06e-14 81.3 COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,4H9T9@91061|Bacilli,1ZBH0@1386|Bacillus 91061|Bacilli S YhgE Pip N-terminal domain protein yhgE - - ko:K01421 - - - - ko00000 - - - ABC2_membrane_3,DUF3533 k141_31164_1 218284.CCDN010000001_gene1082 5.61e-61 194.0 COG4862@1|root,COG4862@2|Bacteria,1UAZ4@1239|Firmicutes,4IMC2@91061|Bacilli,1ZJSC@1386|Bacillus 91061|Bacilli NOT Negative regulator of genetic competence (MecA) - - - ko:K16511 - - - - ko00000 - - - MecA k141_29881_2 218284.CCDN010000001_gene1922 2.39e-32 113.0 COG1582@1|root,COG1582@2|Bacteria,1VKHB@1239|Firmicutes,4HP2W@91061|Bacilli,1ZIYN@1386|Bacillus 91061|Bacilli N protein, possibly involved in motility flbD - - ko:K02385 - - - - ko00000,ko02035 - - - FlbD k141_29881_3 406124.ACPC01000013_gene979 2.11e-37 138.0 COG1749@1|root,COG1749@2|Bacteria,1UHS7@1239|Firmicutes,4IS7Y@91061|Bacilli,1ZS24@1386|Bacillus 91061|Bacilli N flagellar flgE - - ko:K02390 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FlaE,Flg_bb_rod,Flg_bbr_C k141_25168_1 1500304.JQKY01000008_gene2970 2.41e-07 58.2 COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2TQVN@28211|Alphaproteobacteria,4B81Q@82115|Rhizobiaceae 28211|Alphaproteobacteria T Adenylate - - - - - - - - - - - - AAA_16,DZR,Guanylate_cyc,SAM_1 k141_20352_1 218284.CCDN010000001_gene1956 6.23e-106 315.0 COG2718@1|root,COG2718@2|Bacteria,1TQIN@1239|Firmicutes,4HBIH@91061|Bacilli,1ZATH@1386|Bacillus 91061|Bacilli S Belongs to the UPF0229 family yhbH - - ko:K09786 - - - - ko00000 - - - DUF444 k141_33468_1 218284.CCDN010000001_gene1141 2.24e-107 334.0 COG0847@1|root,COG1199@1|root,COG0847@2|Bacteria,COG1199@2|Bacteria,1TQHQ@1239|Firmicutes,4HB2Y@91061|Bacilli,1ZAWI@1386|Bacillus 91061|Bacilli L helicase involved in DNA repair and perhaps also replication dinG - 3.6.4.12 ko:K03722 - - - - ko00000,ko01000,ko03400 - - - DEAD,Helicase_C_2,RNase_T,ResIII k141_15682_1 1453501.JELR01000001_gene2864 6.57e-192 561.0 COG0457@1|root,COG0457@2|Bacteria,1MX2U@1224|Proteobacteria,1RPD2@1236|Gammaproteobacteria,464NG@72275|Alteromonadaceae 1236|Gammaproteobacteria C Cytochrome c554 and c-prime - - - - - - - - - - - - Cytochrome_C554,HEAT_2,Paired_CXXCH_1,TPR_16,TPR_19,TPR_20,TPR_8 k141_15682_2 1116375.VEJY3_23011 1.06e-57 197.0 COG2207@1|root,COG2207@2|Bacteria,1MX23@1224|Proteobacteria,1RXXK@1236|Gammaproteobacteria,1XVU6@135623|Vibrionales 135623|Vibrionales K AraC-type DNA-binding domain-containing - - - - - - - - - - - - Arabinose_bd,HTH_18 k141_15682_3 1177179.A11A3_11488 2.12e-18 92.4 COG2207@1|root,COG2207@2|Bacteria,1RENI@1224|Proteobacteria,1S6HJ@1236|Gammaproteobacteria,1XPMQ@135619|Oceanospirillales 135619|Oceanospirillales K transcriptional regulator - - - - - - - - - - - - Arabinose_bd,HTH_18 k141_15682_4 1042377.AFPJ01000020_gene2058 3.55e-256 715.0 COG2072@1|root,COG2072@2|Bacteria,1MU71@1224|Proteobacteria,1RP8X@1236|Gammaproteobacteria,465CT@72275|Alteromonadaceae 1236|Gammaproteobacteria P flavoprotein involved in K transport ethA - - - - - - - - - - - FMO-like,NAD_binding_8,Pyr_redox_2,Pyr_redox_3 k141_15682_5 1279017.AQYJ01000025_gene516 0.0 933.0 COG1292@1|root,COG1292@2|Bacteria,1MV0K@1224|Proteobacteria,1RP3E@1236|Gammaproteobacteria,46AAG@72275|Alteromonadaceae 1236|Gammaproteobacteria P Belongs to the BCCT transporter (TC 2.A.15) family cudT - - ko:K03451 - - - - ko00000 2.A.15 - - BCCT k141_15682_6 1042377.AFPJ01000020_gene2057 1.25e-201 578.0 COG1502@1|root,COG1502@2|Bacteria,1MUDJ@1224|Proteobacteria,1RMIF@1236|Gammaproteobacteria,4649V@72275|Alteromonadaceae 1236|Gammaproteobacteria I Phospholipase D. Active site motifs. - - - ko:K06132 ko00564,ko01100,map00564,map01100 - R11062 RC00017 ko00000,ko00001,ko01000 - - - PLDc_2 k141_15682_7 1126627.BAWE01000004_gene3042 2.23e-50 172.0 COG1073@1|root,COG1765@1|root,COG1073@2|Bacteria,COG1765@2|Bacteria,1N2BT@1224|Proteobacteria,2TQN7@28211|Alphaproteobacteria,3JQSS@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O OsmC-like protein MA20_16590 - - ko:K06889,ko:K07397 - - - - ko00000 - - - Hydrolase_4,OsmC k141_9674_1 1042377.AFPJ01000009_gene217 5.92e-36 131.0 COG0679@1|root,COG0679@2|Bacteria,1N1X9@1224|Proteobacteria,1RMV0@1236|Gammaproteobacteria,466VU@72275|Alteromonadaceae 1236|Gammaproteobacteria S Auxin Efflux Carrier - - - ko:K07088 - - - - ko00000 - - - Mem_trans k141_6251_1 478741.JAFS01000002_gene224 1.35e-40 155.0 COG1034@1|root,COG3383@1|root,COG1034@2|Bacteria,COG3383@2|Bacteria,46S6S@74201|Verrucomicrobia,37G1Z@326457|unclassified Verrucomicrobia 74201|Verrucomicrobia C NADH-ubiquinone oxidoreductase-G iron-sulfur binding region nuoG - 1.6.5.3 ko:K00336 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Fer2_4,Molybdop_Fe4S4,Molybdopterin,NADH-G_4Fe-4S_3 k141_291_1 1123401.JHYQ01000012_gene2941 6.79e-73 235.0 COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,1RPZC@1236|Gammaproteobacteria,45ZU4@72273|Thiotrichales 72273|Thiotrichales J Beta-Casp domain - - - ko:K07576 - - - - ko00000 - - - Beta-Casp,Lactamase_B,RMMBL k141_37007_1 1136163.M565_ctg5P0922 5.58e-105 307.0 COG3501@1|root,COG3501@2|Bacteria,1RI4Z@1224|Proteobacteria,1S716@1236|Gammaproteobacteria,1XWKJ@135623|Vibrionales 135623|Vibrionales S Rhs element vgr protein - - - - - - - - - - - - - k141_37007_2 1136163.M565_ctg5P0921 3.61e-129 372.0 COG3501@1|root,COG3501@2|Bacteria,1P4HU@1224|Proteobacteria,1RV4P@1236|Gammaproteobacteria,1XXRT@135623|Vibrionales 135623|Vibrionales S Rhs element vgr protein - - - - - - - - - - - - - k141_37007_3 312309.VF_2024 3.19e-18 77.4 2EKQE@1|root,33EE7@2|Bacteria,1NM14@1224|Proteobacteria,1SHF2@1236|Gammaproteobacteria,1XZHD@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_37007_5 1116375.VEJY3_10975 6.18e-112 323.0 COG3531@1|root,COG3531@2|Bacteria,1RIN9@1224|Proteobacteria,1RS8P@1236|Gammaproteobacteria,1XUUK@135623|Vibrionales 135623|Vibrionales O Protein-disulfide isomerase VP2116 - - ko:K07396 - - - - ko00000 - - - Thioredoxin_5 k141_28786_1 42565.FP66_11830 5.29e-97 283.0 COG0632@1|root,COG0632@2|Bacteria,1MWJR@1224|Proteobacteria,1RMET@1236|Gammaproteobacteria,1XJI5@135619|Oceanospirillales 135619|Oceanospirillales L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB ruvA - 3.6.4.12 ko:K03550 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - HHH_5,RuvA_C,RuvA_N k141_10864_2 1279017.AQYJ01000027_gene1570 2.69e-233 652.0 COG0860@1|root,COG0860@2|Bacteria,1MUQK@1224|Proteobacteria,1RMP1@1236|Gammaproteobacteria,4647N@72275|Alteromonadaceae 1236|Gammaproteobacteria M N-acetylmuramoyl-L-alanine amidase amiC - 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - AMIN,Amidase_3,LysM k141_10864_3 1279017.AQYJ01000027_gene1571 2.04e-74 226.0 COG0802@1|root,COG0802@2|Bacteria,1RGYU@1224|Proteobacteria,1S6IB@1236|Gammaproteobacteria,467AG@72275|Alteromonadaceae 1236|Gammaproteobacteria S ATPase or kinase yjeE GO:0000166,GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043531,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 - ko:K06925 - - - - ko00000,ko03016 - - - TsaE k141_10864_4 1279017.AQYJ01000027_gene1572 9.17e-40 143.0 COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,1RMPS@1236|Gammaproteobacteria,4654W@72275|Alteromonadaceae 1236|Gammaproteobacteria G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration nnrD GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 - - - - ko00000,ko01000 - - - Carb_kinase,YjeF_N k141_16832_1 218284.CCDN010000002_gene2345 1.28e-68 212.0 COG0454@1|root,COG0456@2|Bacteria,1UIVT@1239|Firmicutes,4ISTU@91061|Bacilli,1ZS6U@1386|Bacillus 91061|Bacilli K Acetyltransferase (GNAT) family ybbJ - - - - - - - - - - - Acetyltransf_1 k141_16832_2 218284.CCDN010000002_gene2276 8.94e-45 150.0 2BZUV@1|root,33GRN@2|Bacteria,1VPDM@1239|Firmicutes,4HS52@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - k141_16832_3 1034347.CAHJ01000004_gene1203 4.49e-23 92.0 COG4194@1|root,COG4194@2|Bacteria,1V3Z3@1239|Firmicutes,4HHRK@91061|Bacilli,1ZG9F@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF1648) - - - - - - - - - - - - DUF1648 k141_22778_1 1121374.KB891587_gene3024 2.8e-43 151.0 COG0596@1|root,COG0596@2|Bacteria,1MVVX@1224|Proteobacteria,1T3KJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 k141_22778_2 1415778.JQMM01000001_gene2193 3.08e-133 396.0 COG0183@1|root,COG0183@2|Bacteria,1MU8C@1224|Proteobacteria,1RNDU@1236|Gammaproteobacteria,1JA8A@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria I Thiolase, C-terminal domain - - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N k141_22778_3 1120953.AUBH01000005_gene2328 1.81e-138 410.0 COG0318@1|root,COG0318@2|Bacteria,1MWSD@1224|Proteobacteria,1RQ1C@1236|Gammaproteobacteria,466HP@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ AMP-binding enzyme C-terminal domain - - 6.2.1.48 ko:K02182 - - - - ko00000,ko01000 - - - AMP-binding,AMP-binding_C k141_35825_1 1287116.X734_00600 2.02e-18 79.3 COG3415@1|root,COG3415@2|Bacteria,1RJ69@1224|Proteobacteria,2UCXQ@28211|Alphaproteobacteria,43REE@69277|Phyllobacteriaceae 28211|Alphaproteobacteria L 'Paired box' domain - - - ko:K07499 - - - - ko00000 - - - HTH_23,HTH_28,HTH_32,HTH_Tnp_IS630,HTH_Tnp_Tc3_2 k141_35825_2 1410620.SHLA_42c000680 2.35e-39 134.0 COG0309@1|root,COG0309@2|Bacteria,1NAXH@1224|Proteobacteria,2UFGK@28211|Alphaproteobacteria 28211|Alphaproteobacteria O Transposase DDE domain - - - - - - - - - - - - DDE_Tnp_1_2 k141_26741_3 1042377.AFPJ01000014_gene1652 0.0 1264.0 COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,1RNEB@1236|Gammaproteobacteria,465F9@72275|Alteromonadaceae 1236|Gammaproteobacteria J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner valS GO:0000287,GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006417,GO:0006418,GO:0006438,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0034248,GO:0034250,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045903,GO:0046483,GO:0046872,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0052689,GO:0060255,GO:0061475,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:2000112 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iECH74115_1262.ECH74115_5779,iECNA114_1301.ECNA114_4481,iECO26_1355.ECO26_5428,iECSP_1301.ECSP_5359,iECs_1301.ECs5235,iG2583_1286.G2583_5088,iJN746.PP_0977,iSBO_1134.SBO_4182,iSSON_1240.SSON_4443,iYL1228.KPN_04663,iZ_1308.Z5870 Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 k141_19413_1 946483.Cenrod_1456 8.17e-56 191.0 COG5316@1|root,COG5316@2|Bacteria,1QCVP@1224|Proteobacteria,2VNEJ@28216|Betaproteobacteria 28216|Betaproteobacteria S Domain of unknown function (DUF4139) - - - - - - - - - - - - DUF4139 k141_13588_1 1453501.JELR01000001_gene2396 6.32e-101 303.0 COG3975@1|root,COG3975@2|Bacteria,1QX25@1224|Proteobacteria,1RWD8@1236|Gammaproteobacteria,466PD@72275|Alteromonadaceae 1236|Gammaproteobacteria S protease with the C-terminal PDZ domain - - - - - - - - - - - - - k141_4048_1 218284.CCDN010000001_gene34 1.2e-155 451.0 COG1461@1|root,COG1461@2|Bacteria,1TQMX@1239|Firmicutes,4HBSE@91061|Bacilli,1ZBRP@1386|Bacillus 91061|Bacilli S kinase related to dihydroxyacetone kinase yloV - - ko:K07030 - - - - ko00000 - - - Dak1_2,Dak2 k141_24132_1 1298863.AUEP01000005_gene2438 1.97e-05 51.6 COG0842@1|root,COG0842@2|Bacteria,2GN6S@201174|Actinobacteria,4DQ7H@85009|Propionibacteriales 201174|Actinobacteria V ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane,ABC2_membrane_3 k141_34838_1 218284.CCDN010000002_gene2843 1.9e-93 279.0 COG1737@1|root,COG1737@2|Bacteria,1TR0N@1239|Firmicutes,4HB9E@91061|Bacilli,1ZCCD@1386|Bacillus 91061|Bacilli K RpiR family transcriptional regulator - - - - - - - - - - - - HTH_6,SIS k141_34838_2 218284.CCDN010000002_gene2842 2.47e-68 207.0 COG1447@1|root,COG1447@2|Bacteria,1VEGE@1239|Firmicutes,4HNWK@91061|Bacilli,1ZIK1@1386|Bacillus 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIA subunit - - 2.7.1.196,2.7.1.205 ko:K02759 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 - - PTS_IIA k141_34838_3 218284.CCDN010000002_gene2841 7.21e-49 165.0 COG3589@1|root,COG3589@2|Bacteria,1TRIY@1239|Firmicutes,4H9V2@91061|Bacilli,1ZDI0@1386|Bacillus 91061|Bacilli S Bacterial protein of unknown function (DUF871) - - - ko:K09963 - - - - ko00000 - - - DUF871 k141_18283_1 1168065.DOK_17530 1.11e-33 127.0 COG0672@1|root,COG0672@2|Bacteria,1N48M@1224|Proteobacteria,1S7GF@1236|Gammaproteobacteria,1J6PW@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P COG0672 High-affinity Fe2 Pb2 permease - - - ko:K07243 - - - - ko00000,ko02000 2.A.108.1,2.A.108.2 - - FTR1 k141_23056_1 1116375.VEJY3_06360 4.38e-91 283.0 COG1164@1|root,COG1164@2|Bacteria,1MXAC@1224|Proteobacteria,1S6M5@1236|Gammaproteobacteria,1XVUU@135623|Vibrionales 135623|Vibrionales E COG1164 Oligoendopeptidase F - - - ko:K08602 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M3,Peptidase_M3_N k141_2765_1 218284.CCDN010000001_gene43 3.1e-138 403.0 COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1TP3N@1239|Firmicutes,4HBQ6@91061|Bacilli,1ZCWU@1386|Bacillus 91061|Bacilli J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA sun GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 ko:K03500 - - - - ko00000,ko01000,ko03009 - - - Methyltr_RsmB-F,Methyltr_RsmF_N,NusB k141_25381_1 674977.VMC_30290 2.82e-41 142.0 2BHEN@1|root,32BGN@2|Bacteria,1QK9U@1224|Proteobacteria,1TIDB@1236|Gammaproteobacteria,1XYX3@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_25381_2 1116375.VEJY3_17776 9.38e-311 850.0 COG0038@1|root,COG0038@2|Bacteria,1MV4K@1224|Proteobacteria,1RQJW@1236|Gammaproteobacteria,1XT8H@135623|Vibrionales 135623|Vibrionales P Probably acts as an electrical shunt for an outwardly- directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response clcA - - ko:K03281 - - - - ko00000 2.A.49 - - Voltage_CLC k141_32382_2 218284.CCDN010000002_gene2103 2.11e-76 233.0 COG1101@1|root,COG1101@2|Bacteria,1TPAN@1239|Firmicutes,4HCHC@91061|Bacilli,1ZCBE@1386|Bacillus 91061|Bacilli S transport system, ATPase component - - - ko:K05833 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_tran k141_7483_1 218284.CCDN010000001_gene1159 8.63e-21 93.6 COG3359@1|root,COG3359@2|Bacteria,1TQQU@1239|Firmicutes,4HDMU@91061|Bacilli,1ZAZQ@1386|Bacillus 91061|Bacilli L RNase_H superfamily yprB - - ko:K07502 - - - - ko00000 - - - RNase_H_2 k141_7483_2 441769.ABFU01000038_gene131 3.34e-34 120.0 2EHDE@1|root,33B59@2|Bacteria,1VPT6@1239|Firmicutes,4HRKG@91061|Bacilli,1ZGH5@1386|Bacillus 91061|Bacilli S Inner spore coat protein D cotD - - ko:K06327 - - - - ko00000 - - - Spore-coat_CotD k141_11106_1 1379270.AUXF01000006_gene290 5.45e-102 321.0 COG0322@1|root,COG0322@2|Bacteria,1ZSXE@142182|Gemmatimonadetes 142182|Gemmatimonadetes L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision uvrC - - ko:K03703 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - GIY-YIG,HHH_5,UVR,UvrC_HhH_N k141_8770_2 1294265.JCM21738_4742 9.69e-73 222.0 COG0517@1|root,COG0517@2|Bacteria,1V0XU@1239|Firmicutes,4HD12@91061|Bacilli,1ZBNZ@1386|Bacillus 91061|Bacilli S Acetoin utilization protein AcuB acuB - - ko:K04767 - - - - ko00000 - - - ACT,CBS k141_15838_2 483219.LILAB_27985 6.6e-29 117.0 COG0464@1|root,COG0464@2|Bacteria,1MXFG@1224|Proteobacteria,42PBF@68525|delta/epsilon subdivisions,2WJG0@28221|Deltaproteobacteria 28221|Deltaproteobacteria O ATPase with chaperone activity - - - - - - - - - - - - - k141_30017_1 1453501.JELR01000002_gene459 1.27e-71 229.0 COG1657@1|root,COG1657@2|Bacteria,1R5W8@1224|Proteobacteria,1T312@1236|Gammaproteobacteria,465YU@72275|Alteromonadaceae 1236|Gammaproteobacteria I Pectic acid lyase pel10A - - - - - - - - - - - CBM_2,CBM_6,Pec_lyase k141_18284_1 218284.CCDN010000010_gene4327 0.000611 42.0 COG2194@1|root,COG2194@2|Bacteria,1UZ64@1239|Firmicutes,4HFDE@91061|Bacilli,1ZFN5@1386|Bacillus 91061|Bacilli S Involved in the activation of the KinB signaling pathway of sporulation kbaA GO:0008150,GO:0022603,GO:0042173,GO:0043937,GO:0043938,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0065007 - ko:K06349 - - - - ko00000 - - - KbaA k141_21798_1 709991.Odosp_3142 1.35e-25 108.0 COG0249@1|root,COG0249@2|Bacteria,4NEXA@976|Bacteroidetes,2FQ2D@200643|Bacteroidia,22ZFQ@171551|Porphyromonadaceae 976|Bacteroidetes L MutS domain III - - - - - - - - - - - - MutS_III,MutS_V k141_21798_2 1279017.AQYJ01000028_gene2141 2.46e-148 422.0 COG3248@1|root,COG3248@2|Bacteria,1RC26@1224|Proteobacteria,1S3EM@1236|Gammaproteobacteria,46DI2@72275|Alteromonadaceae 1236|Gammaproteobacteria M Nucleoside-specific channel-forming protein, Tsx - - - - - - - - - - - - Channel_Tsx,DUF5020 k141_21798_3 1042377.AFPJ01000053_gene1515 5.54e-257 712.0 COG2252@1|root,COG2252@2|Bacteria,1MUV0@1224|Proteobacteria,1RMBE@1236|Gammaproteobacteria,464EG@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG2252 Permeases purP - - ko:K06901 - - - - ko00000,ko02000 2.A.1.40 - - Xan_ur_permease k141_17037_1 195250.CM001776_gene2195 7.61e-20 94.7 COG0795@1|root,COG0795@2|Bacteria,1G14H@1117|Cyanobacteria,1GZDN@1129|Synechococcus 1117|Cyanobacteria S Permease, YjgP YjgQ family ycf84 - - ko:K11720 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko02000 1.B.42.1 - - YjgP_YjgQ k141_24133_1 1279017.AQYJ01000028_gene2353 2.23e-88 265.0 COG1309@1|root,COG1309@2|Bacteria,1RESV@1224|Proteobacteria,1S55T@1236|Gammaproteobacteria,467HH@72275|Alteromonadaceae 1236|Gammaproteobacteria K Transcriptional regulator - - - ko:K19736 - - - - ko00000,ko03000 - - - TetR_C_7,TetR_N k141_23057_1 218284.CCDN010000005_gene3430 2.85e-103 302.0 COG3584@1|root,COG3584@2|Bacteria,1UYMN@1239|Firmicutes,4HIVQ@91061|Bacilli,1ZDD1@1386|Bacillus 91061|Bacilli S protein conserved in bacteria yuiC - - - - - - - - - - - 3D k141_19415_1 439235.Dalk_4167 1.13e-25 105.0 29M87@1|root,3085U@2|Bacteria,1RFIW@1224|Proteobacteria,42ZD2@68525|delta/epsilon subdivisions,2WTTF@28221|Deltaproteobacteria,2MMZC@213118|Desulfobacterales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k141_19415_2 520709.F985_00622 1.43e-19 86.7 COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,1RMXH@1236|Gammaproteobacteria,3NJQZ@468|Moraxellaceae 1236|Gammaproteobacteria S tRNA-splicing ligase RtcB rtcB - 6.5.1.3 ko:K14415 - - - - ko00000,ko01000,ko03016 - - - RtcB k141_8771_1 1144325.PMI22_01402 1.3e-34 135.0 COG0683@1|root,COG2010@1|root,COG0683@2|Bacteria,COG2010@2|Bacteria,1R9N0@1224|Proteobacteria,1S351@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Periplasmic binding protein - - - - - - - - - - - - Cytochrom_C,Peripla_BP_6 k141_14622_2 1453501.JELR01000001_gene2934 7.11e-182 521.0 COG4805@1|root,COG4805@2|Bacteria,1MZDR@1224|Proteobacteria,1RZK8@1236|Gammaproteobacteria,465YN@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein conserved in bacteria - - - - - - - - - - - - - k141_31296_1 1294265.JCM21738_1368 1.03e-95 286.0 COG1252@1|root,COG1252@2|Bacteria,1TPE6@1239|Firmicutes,4H9MY@91061|Bacilli,1ZC0V@1386|Bacillus 91061|Bacilli C NADH dehydrogenase yutJ - 1.6.99.3 ko:K03885 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - Pyr_redox_2 k141_5167_1 218284.CCDN010000002_gene2418 3.13e-56 183.0 COG1708@1|root,COG1708@2|Bacteria,1V17R@1239|Firmicutes,4HFET@91061|Bacilli,1ZFZ9@1386|Bacillus 91061|Bacilli S Nucleotidyltransferase domain - - - - - - - - - - - - Adenyl_transf,NTP_transf_2 k141_5167_2 1196031.ALEG01000069_gene689 2.92e-69 211.0 COG0346@1|root,COG0346@2|Bacteria,1V6MB@1239|Firmicutes,4HHPH@91061|Bacilli,1ZGGB@1386|Bacillus 91061|Bacilli E Glyoxalase bleomycin resistance protein dioxygenase glxI - 4.4.1.5 ko:K01759 ko00620,map00620 - R02530 RC00004,RC00740 ko00000,ko00001,ko01000 - - - Glyoxalase k141_33738_2 1042377.AFPJ01000051_gene79 5.47e-47 169.0 COG3188@1|root,COG3188@2|Bacteria,1MWV6@1224|Proteobacteria,1SZYH@1236|Gammaproteobacteria,46AZV@72275|Alteromonadaceae 1236|Gammaproteobacteria NU Outer membrane usher protein - - - - - - - - - - - - Usher k141_8799_2 1169144.KB910924_gene338 1.82e-186 528.0 COG4695@1|root,COG4695@2|Bacteria,1TRKF@1239|Firmicutes,4HBR6@91061|Bacilli,1ZF4A@1386|Bacillus 91061|Bacilli S Phage portal protein - - - - - - - - - - - - Phage_portal k141_21812_1 674977.VMC_02120 2.66e-105 312.0 COG3219@1|root,COG3219@2|Bacteria,1N7C6@1224|Proteobacteria,1SD3Q@1236|Gammaproteobacteria,1XXFS@135623|Vibrionales 135623|Vibrionales S Putative DNA-binding domain - - - - - - - - - - - - DUF2063 k141_20567_1 218284.CCDN010000006_gene3509 2.36e-55 174.0 COG1393@1|root,COG1393@2|Bacteria,1VA5Q@1239|Firmicutes,4HKQQ@91061|Bacilli,1ZH0I@1386|Bacillus 91061|Bacilli P Belongs to the ArsC family yusI - 1.20.4.1 ko:K00537 - - - - ko00000,ko01000 - - - ArsC,Glutaredoxin k141_14636_1 218284.CCDN010000001_gene1336 1.04e-86 260.0 COG0586@1|root,COG0586@2|Bacteria,1V31C@1239|Firmicutes,4HGNQ@91061|Bacilli,1ZICE@1386|Bacillus 91061|Bacilli S SNARE associated Golgi protein - - - ko:K03975 - - - - ko00000 - - - SNARE_assoc k141_25414_2 666686.B1NLA3E_10640 1.4e-75 228.0 COG0824@1|root,COG0824@2|Bacteria,1VAGM@1239|Firmicutes,4HIVC@91061|Bacilli,1ZG6C@1386|Bacillus 91061|Bacilli S thioesterase yneP - - ko:K07107 - - - - ko00000,ko01000 - - - 4HBT,4HBT_2 k141_25414_4 218284.CCDN010000001_gene1499 7.02e-49 157.0 COG4841@1|root,COG4841@2|Bacteria,1VEQE@1239|Firmicutes,4HNU2@91061|Bacilli,1ZHU4@1386|Bacillus 91061|Bacilli S Belongs to the HesB IscA family yneR - - - - - - - - - - - Fe-S_biosyn k141_30027_1 218284.CCDN010000001_gene947 1.24e-64 204.0 COG1752@1|root,COG1752@2|Bacteria,1TRJW@1239|Firmicutes,4HB8J@91061|Bacilli,1ZC13@1386|Bacillus 91061|Bacilli S esterase of the alpha-beta hydrolase superfamily yqhO GO:0003674,GO:0003824,GO:0016787 - ko:K07001 - - - - ko00000 - - - Patatin k141_30027_2 218284.CCDN010000001_gene948 5.83e-57 179.0 2BYG1@1|root,33M6N@2|Bacteria,1U3TH@1239|Firmicutes,4IC1U@91061|Bacilli,1ZIYH@1386|Bacillus 91061|Bacilli - - yqhP - - - - - - - - - - - - k141_30027_3 218284.CCDN010000001_gene949 1.52e-16 75.5 29VNZ@1|root,30H6A@2|Bacteria,1V5PG@1239|Firmicutes,4HJV5@91061|Bacilli,1ZBD8@1386|Bacillus 91061|Bacilli S Conserved membrane protein YqhR yqhR - - - - - - - - - - - YqhR k141_18303_2 1279017.AQYJ01000027_gene1834 9.49e-150 425.0 COG1349@1|root,COG1349@2|Bacteria,1MUJG@1224|Proteobacteria,1RNW4@1236|Gammaproteobacteria,465X4@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG1349 Transcriptional regulators of sugar metabolism glmR - - - - - - - - - - - DeoRC,HTH_DeoR k141_18303_3 1279017.AQYJ01000027_gene1833 3.48e-145 425.0 COG0508@1|root,COG0508@2|Bacteria,1MVDC@1224|Proteobacteria,1RQ9Y@1236|Gammaproteobacteria,4657Y@72275|Alteromonadaceae 1236|Gammaproteobacteria C 2-oxoacid dehydrogenases acyltransferase (catalytic domain) pdhC - 2.3.1.12,2.3.1.168 ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 M00036,M00307 R00209,R02569,R02662,R03174,R04097,R10998 RC00004,RC02727,RC02742,RC02857,RC02870 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding k141_18303_4 1279017.AQYJ01000027_gene1832 6.64e-201 560.0 COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,1RP3G@1236|Gammaproteobacteria,465NK@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit pdhB - 1.2.4.1 ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C k141_18303_5 1453501.JELR01000002_gene1139 2.61e-181 514.0 COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,1RREX@1236|Gammaproteobacteria,4666W@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit pdhA - 1.2.4.1 ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh k141_18303_6 1279017.AQYJ01000027_gene1830 3.4e-283 779.0 COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,1RNKE@1236|Gammaproteobacteria,465MW@72275|Alteromonadaceae 1236|Gammaproteobacteria M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain glmU GO:0000270,GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006629,GO:0006725,GO:0006793,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009225,GO:0009226,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0018130,GO:0019134,GO:0019438,GO:0030203,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0042546,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0046872,GO:0055086,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903509 2.3.1.157,2.7.7.23 ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00362 R00416,R05332 RC00002,RC00004,RC00166 ko00000,ko00001,ko00002,ko01000 - - iECED1_1282.ECED1_4420,iYL1228.KPN_04135 Hexapep,Hexapep_2,NTP_transf_3 k141_18303_7 1042377.AFPJ01000005_gene2429 0.0 1098.0 COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,1MX3A@1224|Proteobacteria,1RMQZ@1236|Gammaproteobacteria,4641W@72275|Alteromonadaceae 1236|Gammaproteobacteria QU COG0823 Periplasmic component of the Tol biopolymer transport system - - - - - - - - - - - - Amidohydro_1,PD40 k141_8800_1 1453501.JELR01000001_gene3111 2.17e-116 346.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,46A3B@72275|Alteromonadaceae 1236|Gammaproteobacteria C Aldehyde dehydrogenase family - - - - - - - - - - - - Aldedh k141_12432_1 135651.CBN29037 6.2e-05 50.4 COG2866@1|root,KOG2650@2759|Eukaryota,38DUK@33154|Opisthokonta,3BA6U@33208|Metazoa,3CUQS@33213|Bilateria,40JP5@6231|Nematoda,1M30U@119089|Chromadorea,40ZYJ@6236|Rhabditida 33208|Metazoa O Zn_pept CPB2 GO:0001678,GO:0001889,GO:0001990,GO:0001991,GO:0002002,GO:0002003,GO:0002673,GO:0002682,GO:0002697,GO:0002920,GO:0003008,GO:0003013,GO:0003044,GO:0003073,GO:0003081,GO:0003330,GO:0003331,GO:0003674,GO:0003824,GO:0004180,GO:0004181,GO:0005488,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0006325,GO:0006464,GO:0006473,GO:0006475,GO:0006508,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0007039,GO:0007275,GO:0008015,GO:0008150,GO:0008152,GO:0008217,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0008285,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009743,GO:0009746,GO:0009749,GO:0009892,GO:0009987,GO:0010033,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0010755,GO:0010757,GO:0010817,GO:0010955,GO:0012505,GO:0016043,GO:0016485,GO:0016486,GO:0016569,GO:0016570,GO:0016573,GO:0016787,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019222,GO:0019538,GO:0019725,GO:0022603,GO:0030133,GO:0030141,GO:0030162,GO:0030163,GO:0030193,GO:0030194,GO:0030195,GO:0030449,GO:0031099,GO:0031100,GO:0031323,GO:0031324,GO:0031347,GO:0031410,GO:0031982,GO:0032101,GO:0032102,GO:0032103,GO:0032268,GO:0032269,GO:0032501,GO:0032502,GO:0032879,GO:0033500,GO:0034284,GO:0034641,GO:0036211,GO:0042127,GO:0042221,GO:0042445,GO:0042493,GO:0042592,GO:0042593,GO:0042730,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043412,GO:0043543,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0045861,GO:0046872,GO:0046914,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048585,GO:0048731,GO:0048732,GO:0048856,GO:0048878,GO:0050678,GO:0050680,GO:0050727,GO:0050776,GO:0050789,GO:0050793,GO:0050794,GO:0050818,GO:0050819,GO:0050820,GO:0050878,GO:0050886,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051093,GO:0051128,GO:0051130,GO:0051171,GO:0051172,GO:0051239,GO:0051240,GO:0051241,GO:0051246,GO:0051248,GO:0051276,GO:0051603,GO:0051604,GO:0051716,GO:0051917,GO:0051918,GO:0055082,GO:0060255,GO:0061008,GO:0061041,GO:0061045,GO:0065007,GO:0065008,GO:0070011,GO:0070613,GO:0070887,GO:0071310,GO:0071322,GO:0071326,GO:0071331,GO:0071333,GO:0071704,GO:0071840,GO:0080090,GO:0080134,GO:0090303,GO:0097421,GO:0097708,GO:0099503,GO:0140096,GO:1900046,GO:1900047,GO:1900048,GO:1901564,GO:1901565,GO:1901575,GO:1901700,GO:1901701,GO:1903034,GO:1903035,GO:1903036,GO:1903053,GO:1903055,GO:1903317,GO:1903318,GO:1903530,GO:1903532,GO:2000026,GO:2000027,GO:2000257,GO:2000345,GO:2000346 2.7.11.17,3.4.17.1,3.4.17.15,3.4.17.2,3.4.17.20 ko:K01291,ko:K01298,ko:K01300,ko:K04515,ko:K08637,ko:K08779,ko:K08780,ko:K08781 ko04012,ko04020,ko04024,ko04066,ko04114,ko04217,ko04261,ko04310,ko04360,ko04610,ko04614,ko04713,ko04720,ko04722,ko04725,ko04728,ko04740,ko04745,ko04750,ko04911,ko04912,ko04916,ko04921,ko04922,ko04925,ko04934,ko04971,ko04972,ko04974,ko05031,ko05152,ko05200,ko05205,ko05214,map04012,map04020,map04024,map04066,map04114,map04217,map04261,map04310,map04360,map04610,map04614,map04713,map04720,map04722,map04725,map04728,map04740,map04745,map04750,map04911,map04912,map04916,map04921,map04922,map04925,map04934,map04971,map04972,map04974,map05031,map05152,map05200,map05205,map05214 - - - ko00000,ko00001,ko01000,ko01001,ko01002,ko03110 - - - Peptidase_M14,Propep_M14 k141_28931_1 1294265.JCM21738_2920 1.1e-163 458.0 COG0635@1|root,COG0635@2|Bacteria,1TREM@1239|Firmicutes,4HC2D@91061|Bacilli,1ZCRB@1386|Bacillus 91061|Bacilli H coproporphyrinogen III oxidase hemZ - - - - - - - - - - - Radical_SAM k141_19435_2 1123261.AXDW01000001_gene1046 2.46e-06 54.7 COG4106@1|root,COG4106@2|Bacteria,1Q2Y3@1224|Proteobacteria,1S2MJ@1236|Gammaproteobacteria,1X6B4@135614|Xanthomonadales 135614|Xanthomonadales S Methionine biosynthesis protein MetW - - - - - - - - - - - - Methyltransf_11 k141_18304_1 218284.CCDN010000002_gene2596 8.69e-49 168.0 COG4191@1|root,COG4191@2|Bacteria,1UZ9W@1239|Firmicutes,4HDK2@91061|Bacilli,1ZD85@1386|Bacillus 91061|Bacilli T Histidine kinase kinB - 2.7.13.3 ko:K07697 ko02020,map02020 M00485 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - 5TM-5TMR_LYT,HATPase_c,HisKA k141_535_1 1221522.B723_15190 2.38e-27 106.0 COG0725@1|root,COG0725@2|Bacteria,1MVNA@1224|Proteobacteria,1RN71@1236|Gammaproteobacteria,1YMRZ@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria P Molybdate ABC transporter modA - - ko:K02020 ko02010,map02010 M00189 - - ko00000,ko00001,ko00002,ko02000 3.A.1.8 - - SBP_bac_11 k141_535_2 1121935.AQXX01000109_gene502 9.14e-43 145.0 COG4149@1|root,COG4149@2|Bacteria,1MUXR@1224|Proteobacteria,1RRDV@1236|Gammaproteobacteria,1XJ75@135619|Oceanospirillales 135619|Oceanospirillales P (ABC) transporter modB - - ko:K02018 ko02010,map02010 M00189 - - ko00000,ko00001,ko00002,ko02000 3.A.1.8 - - BPD_transp_1 k141_5169_1 1116375.VEJY3_16486 1.3e-271 763.0 COG1129@1|root,COG4177@1|root,COG1129@2|Bacteria,COG4177@2|Bacteria,1R9IW@1224|Proteobacteria,1T36F@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Belongs to the binding-protein-dependent transport system permease family - - - ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C,BPD_transp_2 k141_19436_1 1294265.JCM21738_3373 9.57e-47 153.0 COG3339@1|root,COG3339@2|Bacteria,1VG4I@1239|Firmicutes,4HPVJ@91061|Bacilli,1ZI7U@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF1232) - - - - - - - - - - - - DUF1232 k141_11127_2 1453501.JELR01000001_gene3245 4.31e-249 691.0 2ASXF@1|root,31ID0@2|Bacteria,1RM30@1224|Proteobacteria,1S8I2@1236|Gammaproteobacteria,46BFQ@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_30028_1 1294265.JCM21738_3797 1.34e-184 532.0 COG1305@1|root,COG1305@2|Bacteria,1TP8K@1239|Firmicutes,4HB2E@91061|Bacilli,1ZBUN@1386|Bacillus 91061|Bacilli E COG1305 Transglutaminase-like enzymes yebA - - - - - - - - - - - DUF4129,Transglut_core k141_17049_1 218284.CCDN010000007_gene3965 2.78e-93 287.0 COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,4H9VK@91061|Bacilli,1ZB07@1386|Bacillus 91061|Bacilli G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system - - 3.6.3.17 ko:K02056 - M00221 - - ko00000,ko00002,ko01000,ko02000 3.A.1.2 - - ABC_tran k141_1543_1 1203554.HMPREF1476_00370 7.21e-15 73.9 COG4566@1|root,COG4566@2|Bacteria,1QP7B@1224|Proteobacteria,2W8QM@28216|Betaproteobacteria,4PRV9@995019|Sutterellaceae 28216|Betaproteobacteria K helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE,Response_reg k141_1543_2 1280001.BAOA01000078_gene3130 1.1e-111 340.0 COG3221@1|root,COG4191@1|root,COG3221@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RNNF@1236|Gammaproteobacteria,1XUU5@135623|Vibrionales 135623|Vibrionales T ABC transporter, phosphonate, periplasmic substrate-binding protein - - 2.7.13.3 ko:K13040 ko02020,map02020 M00514 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,Phosphonate-bd k141_21813_1 1348908.KI518618_gene1629 9.52e-128 382.0 COG0029@1|root,COG0029@2|Bacteria,1UHSP@1239|Firmicutes,4H9ZZ@91061|Bacilli,1ZBIE@1386|Bacillus 91061|Bacilli H Catalyzes the oxidation of L-aspartate to iminoaspartate nadB - 1.4.3.16 ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 M00115 R00357,R00481 RC00006,RC02566 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C k141_31297_1 1294265.JCM21738_2913 3.13e-191 538.0 COG0189@1|root,COG0189@2|Bacteria,1TSWS@1239|Firmicutes,4HCJA@91061|Bacilli,1ZAR6@1386|Bacillus 91061|Bacilli HJ YheC/D like ATP-grasp yheD GO:0005575,GO:0005623,GO:0042601,GO:0042763,GO:0044464 - - - - - - - - - - ATPgrasp_YheCD k141_31297_2 1294265.JCM21738_2914 3.72e-40 140.0 COG0189@1|root,COG0189@2|Bacteria,1U4ME@1239|Firmicutes,4HFD2@91061|Bacilli,1ZBNP@1386|Bacillus 91061|Bacilli HJ YheC/D like ATP-grasp yheC - - - - - - - - - - - ATPgrasp_YheCD k141_537_2 985255.APHJ01000019_gene588 5.34e-45 151.0 COG2940@1|root,COG2940@2|Bacteria,4NM5I@976|Bacteroidetes,1I1ME@117743|Flavobacteriia,2P7BX@244698|Gillisia 976|Bacteroidetes S SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain - - - - - - - - - - - - SET k141_27615_1 223926.28805570 2.77e-255 703.0 COG2224@1|root,COG2224@2|Bacteria,1MWIF@1224|Proteobacteria,1RQAK@1236|Gammaproteobacteria,1XTHW@135623|Vibrionales 135623|Vibrionales C Isocitrate lyase aceA - 4.1.3.1 ko:K01637 ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200 M00012 R00479 RC00311,RC00313 ko00000,ko00001,ko00002,ko01000 - - - ICL k141_27615_2 1116375.VEJY3_02665 0.0 1049.0 COG2225@1|root,COG2225@2|Bacteria,1MVEV@1224|Proteobacteria,1RPVI@1236|Gammaproteobacteria,1XSUG@135623|Vibrionales 135623|Vibrionales H Belongs to the malate synthase family aceB - 2.3.3.9 ko:K01638 ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200 M00012 R00472 RC00004,RC00308,RC02747 ko00000,ko00001,ko00002,ko01000 - - - Malate_synthase k141_27615_3 223926.28805567 2.35e-211 584.0 COG0583@1|root,COG0583@2|Bacteria,1MVA1@1224|Proteobacteria,1RPAJ@1236|Gammaproteobacteria,1XSIX@135623|Vibrionales 135623|Vibrionales K Transcriptional regulator - - - ko:K04761 ko02026,map02026 - - - ko00000,ko00001,ko03000 - - - HTH_1,LysR_substrate k141_27615_4 1219076.N646_2737 5.95e-142 400.0 COG0450@1|root,COG0450@2|Bacteria,1MWPY@1224|Proteobacteria,1RN4S@1236|Gammaproteobacteria,1XSFY@135623|Vibrionales 135623|Vibrionales O COG0450 Peroxiredoxin - - 1.11.1.15 ko:K03386 ko04214,map04214 - - - ko00000,ko00001,ko01000,ko04147 - - - 1-cysPrx_C,AhpC-TSA k141_27615_5 1116375.VEJY3_02650 9.08e-141 401.0 COG3142@1|root,COG3142@2|Bacteria,1MV5W@1224|Proteobacteria,1RMC1@1236|Gammaproteobacteria,1XSG9@135623|Vibrionales 135623|Vibrionales P Participates in the control of copper homeostasis cutC GO:0006873,GO:0006875,GO:0006878,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0055065,GO:0055070,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0098771 - ko:K06201 - - - - ko00000 - - - CutC k141_27615_6 223926.28805564 3.83e-72 222.0 COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,1RM9U@1236|Gammaproteobacteria,1XV5N@135623|Vibrionales 135623|Vibrionales S Polyphosphate kinase 2 (PPK2) - - 2.7.4.1 ko:K22468 ko00190,ko03018,map00190,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - PPK2 k141_12436_1 218284.CCDN010000005_gene3304 2.29e-122 352.0 COG0623@1|root,COG0623@2|Bacteria,1TPVD@1239|Firmicutes,4H9YN@91061|Bacilli,1ZAP0@1386|Bacillus 91061|Bacilli I Enoyl- acyl-carrier-protein reductase NADH fabI GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006950,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0033554,GO:0036094,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051716,GO:0055114,GO:0065003,GO:0070417,GO:0071704,GO:0071840,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.3.1.10,1.3.1.9 ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 M00083,M00572 R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671 RC00052,RC00076,RC00120 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 k141_34855_1 1071073.KI530549_gene3503 1.57e-19 88.2 COG1929@1|root,COG1929@2|Bacteria,1TPSI@1239|Firmicutes,4HA91@91061|Bacilli,1ZC1D@1386|Bacillus 91061|Bacilli G Belongs to the glycerate kinase type-1 family glxK - 2.7.1.165 ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 - R08572 RC00002,RC00428 ko00000,ko00001,ko01000 - - - Gly_kinase k141_34855_2 1267600.JFGT01000005_gene2218 9.67e-15 78.2 COG0366@1|root,COG0366@2|Bacteria,1MVKX@1224|Proteobacteria,1RMXP@1236|Gammaproteobacteria,3VZDG@53335|Pantoea 1236|Gammaproteobacteria G Alpha amylase catalytic region ycjM - 2.4.1.7 ko:K00690 ko00500,map00500 - R00803 RC00028 ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,Malt_amylase_C k141_12437_1 1294265.JCM21738_581 1.56e-100 311.0 COG0608@1|root,COG0608@2|Bacteria,1TPXE@1239|Firmicutes,4H9UP@91061|Bacilli,1ZBAT@1386|Bacillus 91061|Bacilli L Single-stranded-DNA-specific exonuclease RecJ recJ - - ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1,ssDNA-exonuc_C k141_8803_1 1294265.JCM21738_5327 2.75e-45 149.0 COG0824@1|root,COG0824@2|Bacteria,1V6GS@1239|Firmicutes,4HJ05@91061|Bacilli,1ZH3F@1386|Bacillus 91061|Bacilli S thioesterase ysmA - - ko:K07107 - - - - ko00000,ko01000 - - - 4HBT,4HBT_2 k141_8803_2 1294265.JCM21738_5325 2.79e-117 338.0 COG2374@1|root,COG2374@2|Bacteria,1VKCH@1239|Firmicutes,4IS9P@91061|Bacilli,1ZS3V@1386|Bacillus 91061|Bacilli S Endonuclease/Exonuclease/phosphatase family - - - ko:K07004 - - - - ko00000 - - - CHB_HEX_C_1,Exo_endo_phos k141_20570_1 218284.CCDN010000001_gene783 3.06e-148 432.0 COG1283@1|root,COG1283@2|Bacteria,1TP4K@1239|Firmicutes,4HAZ0@91061|Bacilli,1ZBHZ@1386|Bacillus 91061|Bacilli P COG1283 Na phosphate symporter yjbB - - ko:K03324 - - - - ko00000,ko02000 2.A.58.2 - - Na_Pi_cotrans,PhoU k141_20570_2 218284.CCDN010000001_gene782 1.08e-23 96.3 COG5521@1|root,COG5521@2|Bacteria,1V2MC@1239|Firmicutes,4HGIF@91061|Bacilli,1ZBMN@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF1189) yqgB - - - - - - - - - - - DUF1189 k141_28933_1 1294265.JCM21738_1784 3.57e-212 603.0 COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,1TQIX@1239|Firmicutes,4HUSZ@91061|Bacilli,1ZCA1@1386|Bacillus 91061|Bacilli C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - 1.17.1.9 ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001,ko01000 - - - Molybdopterin,Molydop_binding k141_5172_1 1535422.ND16A_1984 1.07e-60 204.0 COG0457@1|root,COG0457@2|Bacteria,1N0A9@1224|Proteobacteria,1RZSZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S COG0457 FOG TPR repeat - - - - - - - - - - - - - k141_11129_1 997296.PB1_11734 2.53e-35 125.0 COG2011@1|root,COG2011@2|Bacteria,1TSJS@1239|Firmicutes,4HAZD@91061|Bacilli,1ZRMX@1386|Bacillus 91061|Bacilli P COG2011 ABC-type metal ion transport system, permease component metP_2 - - ko:K02072 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - BPD_transp_1 k141_11129_2 1294265.JCM21738_4819 1.19e-112 328.0 COG1464@1|root,COG1464@2|Bacteria,1TRXS@1239|Firmicutes,4HAD4@91061|Bacilli,1ZBWI@1386|Bacillus 91061|Bacilli P COG1464 ABC-type metal ion transport system, periplasmic component surface antigen - - - ko:K02073 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - Lipoprotein_9 k141_19438_2 1453501.JELR01000001_gene3115 1.37e-37 134.0 COG2013@1|root,COG2013@2|Bacteria,1R28E@1224|Proteobacteria,1T5IR@1236|Gammaproteobacteria,46DC3@72275|Alteromonadaceae 1236|Gammaproteobacteria S TIGRFAM TIGR00266 family protein - - - - - - - - - - - - - k141_13935_11 1116375.VEJY3_17096 1.31e-122 351.0 COG0431@1|root,COG0431@2|Bacteria,1RAFI@1224|Proteobacteria,1RYNR@1236|Gammaproteobacteria,1XZV5@135623|Vibrionales 135623|Vibrionales S NADPH-dependent FMN reductase - - - ko:K19784 - - - - ko00000 - - - FMN_red k141_13935_13 1117647.M5M_10405 4.1e-82 273.0 COG0810@1|root,COG5297@1|root,COG0810@2|Bacteria,COG5297@2|Bacteria,1R2EB@1224|Proteobacteria 1224|Proteobacteria M Belongs to the glycosyl hydrolase family 6 - - - - - - - - - - - - - k141_13935_14 443152.MDG893_15892 1.78e-59 204.0 28M8D@1|root,311HE@2|Bacteria,1RFC1@1224|Proteobacteria,1S52R@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Catalyzes the depolymerization of alginate by cleaving the beta-1,4 glycosidic bond between two adjacent sugar residues via a beta-elimination mechanism algL - 4.2.2.3 ko:K01729 ko00051,map00051 - R03706 - ko00000,ko00001,ko01000 - - - Alginate_lyase k141_13935_16 1123020.AUIE01000014_gene308 1.02e-49 186.0 COG3420@1|root,COG3420@2|Bacteria,1R61J@1224|Proteobacteria,1RQM9@1236|Gammaproteobacteria,1YDXG@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria P Domain present in carbohydrate binding proteins and sugar hydrolses algG - 5.1.3.37 ko:K01795 ko00051,map00051 - R08693 RC00509 ko00000,ko00001,ko01000 - - - Beta_helix,NosD k141_13935_18 595494.Tola_1409 6.59e-67 224.0 COG0845@1|root,COG0845@2|Bacteria,1N6KD@1224|Proteobacteria,1S37T@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Alginate biosynthesis protein Alg44 alg44 - 2.4.1.33 ko:K19291 ko00051,ko02025,map00051,map02025 - R08692 RC00005 ko00000,ko00001,ko01000 - - - HlyD_3,PilZ k141_13935_19 595494.Tola_1408 3.46e-251 701.0 COG1215@1|root,COG1215@2|Bacteria,1NQ1J@1224|Proteobacteria,1RYM8@1236|Gammaproteobacteria 1236|Gammaproteobacteria M COG1215 Glycosyltransferases, probably involved in cell wall biogenesis alg8 - 2.4.1.33 ko:K19290 ko00051,map00051 - R08692 RC00005 ko00000,ko00001,ko01000,ko01003,ko02000 4.D.1.1.7,4.D.1.1.9 GT2 - Glyco_tranf_2_3 k141_13935_20 743720.Psefu_3880 4.05e-189 539.0 COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,1RPAC@1236|Gammaproteobacteria,1YXFC@136845|Pseudomonas putida group 1236|Gammaproteobacteria M Belongs to the UDP-glucose GDP-mannose dehydrogenase family algD - 1.1.1.132,1.1.1.22 ko:K00012,ko:K00066 ko00040,ko00051,ko00053,ko00520,ko01100,ko02020,map00040,map00051,map00053,map00520,map01100,map02020 M00014,M00129,M00361,M00362 R00286,R00880 RC00291 ko00000,ko00001,ko00002,ko01000 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N k141_13935_21 1278307.KB907004_gene140 2.02e-213 603.0 COG0836@1|root,COG0836@2|Bacteria,1MV39@1224|Proteobacteria,1RNQI@1236|Gammaproteobacteria,2QIS8@267894|Psychromonadaceae 1236|Gammaproteobacteria M Mannose-6-phosphate isomerase cpsB GO:0000271,GO:0003674,GO:0003824,GO:0004475,GO:0005975,GO:0005976,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0008152,GO:0008905,GO:0008928,GO:0009058,GO:0009059,GO:0009242,GO:0009628,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016772,GO:0016779,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046377,GO:0050896,GO:0070568,GO:0071704,GO:1901135,GO:1901137,GO:1901576 2.7.7.13,5.3.1.8 ko:K00971,ko:K16011 ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025 M00114,M00361,M00362 R00885,R01819 RC00002,RC00376 ko00000,ko00001,ko00002,ko01000 - - iE2348C_1286.E2348C_2191,iEC042_1314.EC042_2286,iECIAI1_1343.ECIAI1_2124,iECO26_1355.ECO26_2960,iECSE_1348.ECSE_2323,iECW_1372.ECW_m2206,iEKO11_1354.EKO11_1746,iEcE24377_1341.EcE24377A_2342,iLF82_1304.LF82_0345,iNRG857_1313.NRG857_10420,iWFL_1372.ECW_m2206 MannoseP_isomer,NTP_transferase k141_13935_22 273526.SMDB11_0869 3.46e-239 668.0 COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,1RMU8@1236|Gammaproteobacteria,400NN@613|Serratia 1236|Gammaproteobacteria G Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III manB - 5.4.2.8 ko:K01840 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 M00114 R01818 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV k141_13935_23 595494.Tola_1417 8.26e-51 191.0 COG3420@1|root,COG3420@2|Bacteria,1R61J@1224|Proteobacteria 1224|Proteobacteria P Poly(Beta-D-mannuronate) C5 epimerase - - 5.1.3.37 ko:K01795 ko00051,map00051 - R08693 RC00509 ko00000,ko00001,ko01000 - - - Beta_helix k141_5548_1 218284.CCDN010000006_gene3746 7.91e-99 316.0 COG3459@1|root,COG3459@2|Bacteria,1TVMK@1239|Firmicutes,4H9ZP@91061|Bacilli,1ZF4F@1386|Bacillus 91061|Bacilli G Glycosyl hydrolase 36 superfamily, catalytic domain chvB1 - 2.4.1.20,2.4.1.333 ko:K00702,ko:K13688,ko:K21298 ko00500,ko01100,map00500,map01100 - R00952 RC00049 ko00000,ko00001,ko01000,ko01003 - GH94,GT36,GT84 - Glyco_hydro_36,Glyco_transf_36 k141_35202_2 377629.TERTU_2974 2.37e-08 57.8 COG3064@1|root,COG4656@1|root,COG3064@2|Bacteria,COG4656@2|Bacteria,1QTUI@1224|Proteobacteria,1RMIM@1236|Gammaproteobacteria,2PNAH@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria CM Respiratory-chain NADH dehydrogenase 51 Kd subunit rnfC GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0055114 - ko:K03615 - - - - ko00000 - - - Complex1_51K,Fer4_10,Fer4_7,Fer4_8,RnfC_N,SLBB k141_18630_1 10724.Q38150_BPSPP 5.57e-18 82.0 4QAX8@10239|Viruses,4QVB1@35237|dsDNA viruses no RNA stage,4QPHH@28883|Caudovirales,4QKTJ@10699|Siphoviridae 10699|Siphoviridae S calcium ion binding - - - - - - - - - - - - - k141_18630_2 1453500.AT05_04225 2.95e-19 95.1 COG0305@1|root,COG0305@2|Bacteria,4NF8P@976|Bacteroidetes,1HWS1@117743|Flavobacteriia 976|Bacteroidetes L Participates in initiation and elongation during chromosome replication dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k141_11489_1 1294265.JCM21738_1938 4.51e-43 144.0 COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,4HA2S@91061|Bacilli,1ZAUS@1386|Bacillus 91061|Bacilli P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components oppB - - ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - BPD_transp_1 k141_11489_2 1347086.CCBA010000027_gene3469 3.46e-27 108.0 COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,4HAMK@91061|Bacilli,1ZBB4@1386|Bacillus 91061|Bacilli E ABC transporter substrate-binding protein oppA - - ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 k141_14841_1 1279017.AQYJ01000024_gene1075 1.3e-232 658.0 COG3107@1|root,COG3107@2|Bacteria,1MUHR@1224|Proteobacteria,1RXX4@1236|Gammaproteobacteria,465I7@72275|Alteromonadaceae 1236|Gammaproteobacteria M (Lipo)protein lpoA GO:0000270,GO:0003674,GO:0005575,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009279,GO:0009987,GO:0016020,GO:0019867,GO:0030203,GO:0030234,GO:0030312,GO:0030313,GO:0031241,GO:0031975,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044425,GO:0044462,GO:0044464,GO:0050790,GO:0065007,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0098552,GO:0098772,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 - ko:K07121 - - - - ko00000 - - - LppC k141_14841_2 1101195.Meth11DRAFT_2304 3.81e-28 106.0 COG0792@1|root,COG0792@2|Bacteria,1N6VN@1224|Proteobacteria,2VU20@28216|Betaproteobacteria,2KN5R@206350|Nitrosomonadales 206350|Nitrosomonadales L Belongs to the UPF0102 family - - - ko:K07460 - - - - ko00000 - - - UPF0102 k141_20786_1 1201293.AKXQ01000023_gene4203 5.18e-77 241.0 COG3004@1|root,COG3004@2|Bacteria,1MW15@1224|Proteobacteria,1RNDE@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons nhaA - - ko:K03313 - - - - ko00000,ko02000 2.A.33.1 - - Na_H_antiport_1 k141_9055_1 218284.CCDN010000001_gene219 6.55e-233 652.0 COG1574@1|root,COG1574@2|Bacteria,1TQ6G@1239|Firmicutes,4H9T6@91061|Bacilli,1ZBDY@1386|Bacillus 91061|Bacilli S amidohydrolase nfdA_1 - - - - - - - - - - - Amidohydro_3 k141_27075_1 1279017.AQYJ01000029_gene3582 2.06e-80 268.0 COG1014@1|root,COG4231@1|root,COG1014@2|Bacteria,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,1RSEQ@1236|Gammaproteobacteria,465RF@72275|Alteromonadaceae 1236|Gammaproteobacteria C Pyruvate ferredoxin/flavodoxin oxidoreductase - - 1.2.7.8 ko:K04090 - - - - br01601,ko00000,ko01000 - - - POR,TPP_enzyme_C k141_31409_1 1294265.JCM21738_2377 3.48e-122 354.0 COG1277@1|root,COG1277@2|Bacteria,1TT9E@1239|Firmicutes,4HE5W@91061|Bacilli,1ZDPM@1386|Bacillus 91061|Bacilli S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_2,ABC2_membrane_4 k141_25761_1 218284.CCDN010000002_gene2940 7.79e-167 470.0 COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,4H9YB@91061|Bacilli,1ZBA4@1386|Bacillus 91061|Bacilli E Belongs to the ABC transporter superfamily appF - - ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY k141_32638_1 1279017.AQYJ01000027_gene1683 9.1e-163 489.0 COG5013@1|root,COG5013@2|Bacteria,1MW9S@1224|Proteobacteria,1RQ27@1236|Gammaproteobacteria,465D5@72275|Alteromonadaceae 1236|Gammaproteobacteria C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family narG GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009898,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0031235,GO:0032991,GO:0042126,GO:0043436,GO:0043546,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0097159,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098803,GO:1901363,GO:1902494,GO:1990204,GO:2001057 1.7.5.1 ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 M00529,M00530,M00804 R00798,R01106,R09497 RC02812 ko00000,ko00001,ko00002,ko01000 5.A.3.1 - iSBO_1134.SBO_1842,iUMN146_1321.UM146_09685 Molybdopterin,Molydop_binding,Nitr_red_alph_N k141_2956_1 218284.CCDN010000003_gene2990 1.28e-113 327.0 COG2002@1|root,COG2002@2|Bacteria,1V02A@1239|Firmicutes,4HDIW@91061|Bacilli,1ZAXU@1386|Bacillus 91061|Bacilli K stage V sporulation protein spoVT GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K04769 - - - - ko00000,ko03000 - - - MazE_antitoxin,SpoVT_C k141_12749_1 1196031.ALEG01000067_gene4752 6.7e-101 320.0 COG2866@1|root,COG2866@2|Bacteria,1TSF6@1239|Firmicutes,4HDT5@91061|Bacilli,1ZBGR@1386|Bacillus 91061|Bacilli E Zinc carboxypeptidase - - - - - - - - - - - - Peptidase_M14 k141_23368_2 1051646.VITU9109_21949 0.0 873.0 COG0531@1|root,COG0531@2|Bacteria,1MWXV@1224|Proteobacteria,1RPPM@1236|Gammaproteobacteria,1XV9P@135623|Vibrionales 135623|Vibrionales E COG0531 Amino acid transporters - - - - - - - - - - - - AA_permease_2 k141_7706_1 1279017.AQYJ01000022_gene2657 4.02e-65 209.0 COG2207@1|root,COG2207@2|Bacteria,1P4M5@1224|Proteobacteria,1SB0I@1236|Gammaproteobacteria,46B4Z@72275|Alteromonadaceae 1236|Gammaproteobacteria K helix_turn_helix, arabinose operon control protein - - - - - - - - - - - - HTH_18 k141_7706_2 1279017.AQYJ01000022_gene2656 8.53e-131 378.0 COG3000@1|root,COG3000@2|Bacteria,1PK2T@1224|Proteobacteria,1RWE1@1236|Gammaproteobacteria,46C15@72275|Alteromonadaceae 1236|Gammaproteobacteria I Fatty acid hydroxylase superfamily - - - - - - - - - - - - FA_hydroxylase k141_35204_1 1294265.JCM21738_415 3.79e-128 378.0 COG0243@1|root,COG0243@2|Bacteria,1TPZG@1239|Firmicutes,4HBA3@91061|Bacilli,1ZEAY@1386|Bacillus 91061|Bacilli C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - 1.8.5.3 ko:K07306 ko00920,map00920 - R09501 RC02555 ko00000,ko00001,ko01000,ko02000 5.A.3.3 - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal k141_37420_1 218284.CCDN010000006_gene3680 1.22e-106 313.0 COG2177@1|root,COG2177@2|Bacteria,1TPND@1239|Firmicutes,4HA5A@91061|Bacilli,1ZC4Q@1386|Bacillus 91061|Bacilli D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation ftsX GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0007154,GO:0007165,GO:0007166,GO:0008150,GO:0008356,GO:0009966,GO:0009987,GO:0010033,GO:0010646,GO:0016020,GO:0016043,GO:0019221,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0023052,GO:0032506,GO:0034097,GO:0042173,GO:0042221,GO:0043937,GO:0043938,GO:0044085,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051301,GO:0051716,GO:0065007,GO:0070098,GO:0070297,GO:0070887,GO:0071310,GO:0071345,GO:0071840,GO:0071944,GO:0090529,GO:1902531 - ko:K09811 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - FtsX k141_27839_2 218284.CCDN010000004_gene3052 7.65e-23 96.3 COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,4HG3V@91061|Bacilli,1ZFYF@1386|Bacillus 91061|Bacilli E ATPases associated with a variety of cellular activities - - 3.6.3.25,3.6.3.30 ko:K02010,ko:K02045 ko00920,ko02010,map00920,map02010 M00185,M00190 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.10,3.A.1.6.1,3.A.1.6.3 - - ABC_tran k141_2957_1 1284352.AOIG01000003_gene1063 4.09e-20 94.4 COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,4H9NZ@91061|Bacilli,26R22@186822|Paenibacillaceae 91061|Bacilli L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity mutS2 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K07456 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_V,Smr k141_25763_1 935836.JAEL01000039_gene4822 2.33e-46 152.0 COG0454@1|root,COG0454@2|Bacteria,1UIZH@1239|Firmicutes,4ISYE@91061|Bacilli,1ZS8E@1386|Bacillus 91061|Bacilli K Acetyltransferase (GNAT) family - - - - - - - - - - - - Acetyltransf_1 k141_25763_2 981383.AEWH01000038_gene1213 5.19e-28 105.0 COG0346@1|root,COG0346@2|Bacteria,1V42J@1239|Firmicutes,4HHHX@91061|Bacilli 91061|Bacilli E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - Glyoxalase k141_13938_2 218284.CCDN010000005_gene3271 2.34e-66 211.0 COG1744@1|root,COG1744@2|Bacteria,1UY2H@1239|Firmicutes,4HCI5@91061|Bacilli,1ZBN4@1386|Bacillus 91061|Bacilli S Transcriptional activator protein med med - - ko:K05519,ko:K07335 - - - - ko00000,ko03000 - - - Bmp k141_20787_1 1453501.JELR01000002_gene486 1.77e-71 237.0 COG1629@1|root,COG4771@2|Bacteria,1MUWN@1224|Proteobacteria,1S005@1236|Gammaproteobacteria,46A62@72275|Alteromonadaceae 1236|Gammaproteobacteria P Outer membrane protein beta-barrel family - - - - - - - - - - - - Plug,TonB_dep_Rec k141_32639_2 1430331.EP10_11010 9.11e-08 58.2 COG4191@1|root,COG4191@2|Bacteria,1UZ9W@1239|Firmicutes,4HF45@91061|Bacilli,1WETE@129337|Geobacillus 91061|Bacilli T 5TMR of 5TMR-LYT - - 2.7.13.3 ko:K07697 ko02020,map02020 M00485 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - 5TM-5TMR_LYT,HATPase_c,HisKA k141_35205_2 218284.CCDN010000006_gene3621 4.68e-70 234.0 COG0745@1|root,COG5000@1|root,COG5002@1|root,COG0745@2|Bacteria,COG5000@2|Bacteria,COG5002@2|Bacteria,1U7NI@1239|Firmicutes,4HA3E@91061|Bacilli,1ZCFX@1386|Bacillus 91061|Bacilli T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - GAF,GAF_3,HAMP,HATPase_c,HisKA,Response_reg k141_27078_1 1294265.JCM21738_2679 4.49e-12 60.8 2EBHF@1|root,335HY@2|Bacteria,1VHMW@1239|Firmicutes,4HPZZ@91061|Bacilli,1ZIW2@1386|Bacillus 91061|Bacilli S cell differentiation gerPB - - ko:K06300 - - - - ko00000 - - - GerPB k141_27078_2 1294265.JCM21738_2678 1.69e-82 248.0 2EBJR@1|root,335K6@2|Bacteria,1VF1J@1239|Firmicutes,4HNKG@91061|Bacilli,1ZI2K@1386|Bacillus 91061|Bacilli S Spore germination protein gerPC - - ko:K06301 - - - - ko00000 - - - GerPC k141_18632_1 1445613.JALM01000038_gene2953 4.29e-81 256.0 COG4799@1|root,COG4799@2|Bacteria,2GIRU@201174|Actinobacteria,4DZ29@85010|Pseudonocardiales 201174|Actinobacteria I Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) accD2 - - - - - - - - - - - Carboxyl_trans k141_23371_1 218284.CCDN010000001_gene1329 1.5e-43 147.0 2DR1M@1|root,339SJ@2|Bacteria,1VMD6@1239|Firmicutes,4HRV5@91061|Bacilli,1ZGEB@1386|Bacillus 91061|Bacilli S COG0071 Molecular chaperone (small heat shock protein) yozR - - - - - - - - - - - CS k141_18656_2 1131730.BAVI_19829 5.09e-30 118.0 COG0803@1|root,COG0803@2|Bacteria,1TPG7@1239|Firmicutes,4H9UN@91061|Bacilli,1ZC2Z@1386|Bacillus 91061|Bacilli P Belongs to the bacterial solute-binding protein 9 family adcA - - ko:K09815,ko:K09818 ko02010,map02010 M00242,M00243 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 - - ZnuA k141_17280_1 1279017.AQYJ01000029_gene3473 3.18e-47 156.0 COG1309@1|root,COG1309@2|Bacteria,1N6TK@1224|Proteobacteria,1SCNY@1236|Gammaproteobacteria,4692V@72275|Alteromonadaceae 1236|Gammaproteobacteria K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N k141_17280_2 317025.Tcr_1066 3.44e-43 152.0 COG0531@1|root,COG0531@2|Bacteria,1QXK2@1224|Proteobacteria,1S18B@1236|Gammaproteobacteria 1236|Gammaproteobacteria E amino acid - - - ko:K07076 - - - - ko00000 - - - AA_permease_2 k141_6675_1 1294265.JCM21738_3303 3.73e-66 202.0 COG0561@1|root,COG0561@2|Bacteria,1TR3N@1239|Firmicutes,4HC8P@91061|Bacilli,1ZBP7@1386|Bacillus 91061|Bacilli S Stage IV sporulation yqfD - - ko:K06438 - - - - ko00000 - - - YqfD k141_6675_2 1294265.JCM21738_3302 5.36e-34 117.0 2E4EZ@1|root,32ZA5@2|Bacteria,1VF5C@1239|Firmicutes,4HNQG@91061|Bacilli,1ZHZA@1386|Bacillus 91061|Bacilli S sporulation protein YqfC yqfC - - - - - - - - - - - YabP k141_5578_1 479434.Sthe_1990 5.3e-94 288.0 COG1181@1|root,COG1181@2|Bacteria,2G5RS@200795|Chloroflexi,27XTQ@189775|Thermomicrobia 189775|Thermomicrobia F Belongs to the D-alanine--D-alanine ligase family ddl - 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Dala_Dala_lig_C,Dala_Dala_lig_N k141_16120_1 228405.HNE_2389 1.25e-53 189.0 COG4774@1|root,COG4774@2|Bacteria,1NMCN@1224|Proteobacteria,2TW2G@28211|Alphaproteobacteria,440TB@69657|Hyphomonadaceae 28211|Alphaproteobacteria P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec k141_19743_1 1042377.AFPJ01000037_gene2867 1.57e-36 133.0 COG0354@1|root,COG0354@2|Bacteria,1N852@1224|Proteobacteria,1RPWB@1236|Gammaproteobacteria,466QJ@72275|Alteromonadaceae 1236|Gammaproteobacteria S aminomethyltransferase related to GcvT ygfZ GO:0003674,GO:0005488,GO:0005542,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0019842,GO:0022607,GO:0031163,GO:0031406,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0071840,GO:0072341,GO:0097159,GO:1901363 - ko:K06980 - - - - ko00000,ko03016 - - - GCV_T,GCV_T_C k141_19743_4 1453501.JELR01000001_gene1972 3.85e-97 298.0 COG4222@1|root,COG4222@2|Bacteria,1NRU1@1224|Proteobacteria,1SM0C@1236|Gammaproteobacteria 1236|Gammaproteobacteria S DNA topoisomerase IV subunit B - - - - - - - - - - - - Phytase-like k141_34003_1 1279017.AQYJ01000028_gene2069 3.94e-71 219.0 COG0848@1|root,COG0848@2|Bacteria,1RENY@1224|Proteobacteria,1S3TB@1236|Gammaproteobacteria,4681G@72275|Alteromonadaceae 1236|Gammaproteobacteria U Biopolymer transport protein ExbD/TolR - - - - - - - - - - - - ExbD k141_819_1 861299.J421_3216 3.42e-68 218.0 COG3869@1|root,COG3869@2|Bacteria,1ZT9I@142182|Gemmatimonadetes 142182|Gemmatimonadetes F ATP:guanido phosphotransferase, C-terminal catalytic domain - - 2.7.14.1 ko:K19405 - - R11090 RC00002,RC00203 ko00000,ko01000 - - - ATP-gua_Ptrans k141_12771_1 1304883.KI912532_gene2780 4.96e-21 87.8 2E80B@1|root,332EM@2|Bacteria,1N7PZ@1224|Proteobacteria,2VVZX@28216|Betaproteobacteria,2KXET@206389|Rhodocyclales 206389|Rhodocyclales - - - - - - - - - - - - - - - k141_9079_1 1453501.JELR01000005_gene1563 2.53e-95 306.0 COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,1SP6I@1236|Gammaproteobacteria,46516@72275|Alteromonadaceae 1236|Gammaproteobacteria P Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family helA - - ko:K15726 - - - - ko00000,ko02000 2.A.6.1.2 - - ACR_tran k141_23410_1 42565.FP66_14570 5.07e-123 367.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XJHM@135619|Oceanospirillales 135619|Oceanospirillales NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal,dCache_1 k141_11516_1 218284.CCDN010000008_gene4153 2.33e-107 310.0 COG1854@1|root,COG1854@2|Bacteria,1V1CH@1239|Firmicutes,4HFPR@91061|Bacilli,1ZBSW@1386|Bacillus 91061|Bacilli T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) luxS GO:0008150,GO:0043900,GO:0043901,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0065007,GO:1900190,GO:1900191,GO:1900231,GO:1900232 4.4.1.21 ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 M00609 R01291 RC00069,RC01929 ko00000,ko00001,ko00002,ko01000 - - - LuxS k141_17281_1 1042377.AFPJ01000032_gene2753 2.07e-99 292.0 COG0564@1|root,COG0564@2|Bacteria,1MVJ5@1224|Proteobacteria,1RN4N@1236|Gammaproteobacteria,4646S@72275|Alteromonadaceae 1236|Gammaproteobacteria J Responsible for synthesis of pseudouridine from uracil rluA - 5.4.99.28,5.4.99.29 ko:K06177 - - - - ko00000,ko01000,ko03009,ko03016 - - - PseudoU_synth_2 k141_27112_1 796606.BMMGA3_01245 7.85e-113 333.0 COG1181@1|root,COG1181@2|Bacteria,1TP2Y@1239|Firmicutes,4H9KB@91061|Bacilli,1ZDA3@1386|Bacillus 91061|Bacilli F Belongs to the D-alanine--D-alanine ligase family ddl - 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Dala_Dala_lig_C,Dala_Dala_lig_N k141_5579_1 1453501.JELR01000002_gene925 4.87e-21 91.7 COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,1RMUG@1236|Gammaproteobacteria,464H8@72275|Alteromonadaceae 1236|Gammaproteobacteria O HflC and HflK could encode or regulate a protease hflK GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009408,GO:0009628,GO:0009897,GO:0009986,GO:0016020,GO:0016021,GO:0016787,GO:0019538,GO:0031224,GO:0031226,GO:0031233,GO:0032991,GO:0043086,GO:0043170,GO:0044092,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0050790,GO:0050896,GO:0065007,GO:0065009,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0098796,GO:0140096,GO:1901564 - ko:K04088 - M00742 - - ko00000,ko00002,ko01000 - - - Band_7,HflK_N k141_5579_2 1042377.AFPJ01000032_gene2793 2.73e-59 196.0 COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,1RN7V@1236|Gammaproteobacteria,464MZ@72275|Alteromonadaceae 1236|Gammaproteobacteria S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis hflX GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003924,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006417,GO:0006464,GO:0006468,GO:0006518,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006996,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018105,GO:0018193,GO:0018209,GO:0019001,GO:0019222,GO:0019538,GO:0019843,GO:0022411,GO:0030554,GO:0031323,GO:0031326,GO:0032268,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0032790,GO:0032984,GO:0032988,GO:0034248,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0036211,GO:0036289,GO:0043021,GO:0043022,GO:0043023,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0071826,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:2000112 - ko:K03665 - - - - ko00000,ko03009 - - - GTP-bdg_M,GTP-bdg_N,MMR_HSR1 k141_6677_1 218284.CCDN010000008_gene4200 3.27e-30 107.0 2E43M@1|root,32YZY@2|Bacteria,1VAYB@1239|Firmicutes,4HNNI@91061|Bacilli,1ZHTZ@1386|Bacillus 91061|Bacilli S YtzH-like protein ytzH - - - - - - - - - - - YtzH k141_7725_1 1385514.N782_00365 9.77e-106 317.0 COG0659@1|root,COG0659@2|Bacteria,1TT9Y@1239|Firmicutes,4HDPJ@91061|Bacilli,2YBGY@289201|Pontibacillus 91061|Bacilli P Psort location CytoplasmicMembrane, score - - - - - - - - - - - - Xan_ur_permease k141_9080_2 218284.CCDN010000005_gene3443 4.01e-52 165.0 COG2212@1|root,COG2212@2|Bacteria,1VFB4@1239|Firmicutes,4HNQY@91061|Bacilli,1ZI42@1386|Bacillus 91061|Bacilli P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali mrpF - - ko:K05570 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - iYO844.BSU31650 MrpF_PhaF k141_11517_1 671143.DAMO_0047 5.52e-92 274.0 COG0535@1|root,COG0535@2|Bacteria 2|Bacteria I radical SAM domain protein hpnH - - - - - - - - - - - DUF3463,Fer4_12,Fer4_14,Radical_SAM k141_27113_2 1444310.JANV01000096_gene3232 1.12e-38 139.0 COG0270@1|root,COG0270@2|Bacteria,1V3W2@1239|Firmicutes 1239|Firmicutes L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family - - 2.1.1.37 ko:K17398 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko03032,ko03036 - - - DNA_methylase k141_29152_1 42565.FP66_14635 7.73e-193 537.0 COG5361@1|root,COG5361@2|Bacteria,1NBVB@1224|Proteobacteria,1SES6@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Neurotransmitter-gated ion-channel ligand binding domain - - - - - - - - - - - - Neur_chan_LBD,Neur_chan_memb k141_19745_1 218284.CCDN010000002_gene2181 6.85e-199 567.0 COG1502@1|root,COG1502@2|Bacteria,1VSU5@1239|Firmicutes,4HTP4@91061|Bacilli,1ZJTB@1386|Bacillus 91061|Bacilli I Lamin Tail Domain - - - - - - - - - - - - LTD,PLDc_2 k141_10349_1 265729.GS18_0208410 1.54e-87 271.0 COG0402@1|root,COG0402@2|Bacteria,1V147@1239|Firmicutes,4HET1@91061|Bacilli,1ZGSH@1386|Bacillus 91061|Bacilli F S-adenosylhomocysteine deaminase activity - - - - - - - - - - - - Gram_pos_anchor k141_10349_2 621372.ACIH01000146_gene40 1.04e-20 87.8 COG2318@1|root,COG2318@2|Bacteria,1V95A@1239|Firmicutes,4HJF3@91061|Bacilli,26TKB@186822|Paenibacillaceae 91061|Bacilli S DinB superfamily - - - - - - - - - - - - DinB_2 k141_32662_1 1122179.KB890417_gene3309 5.87e-56 197.0 COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes 976|Bacteroidetes T PFAM BNR Asp-box repeat - - - - - - - - - - - - BNR,BNR_6,Sortilin-Vps10 k141_16122_1 260799.BAS2522 2.66e-39 136.0 COG0454@1|root,COG0456@2|Bacteria,1UJ2U@1239|Firmicutes,4IT01@91061|Bacilli 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1 k141_2975_1 1001585.MDS_1585 2.07e-37 142.0 COG2267@1|root,COG2267@2|Bacteria,1QTZP@1224|Proteobacteria,1RPB9@1236|Gammaproteobacteria,1YHC9@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria I Serine aminopeptidase, S33 - - - - - - - - - - - - Abhydrolase_6,Hydrolase_4 k141_2975_2 1042377.AFPJ01000036_gene1195 2.46e-256 712.0 COG2114@1|root,COG2114@2|Bacteria,1MV1V@1224|Proteobacteria,1RYBQ@1236|Gammaproteobacteria,464T6@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) cyaB - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_cyc,MASE2 k141_23413_2 218284.CCDN010000001_gene1156 3.13e-47 157.0 29NR8@1|root,309P6@2|Bacteria,1U5F9@1239|Firmicutes,4IF6W@91061|Bacilli,1ZJ7A@1386|Bacillus 91061|Bacilli S YppG-like protein yppG - - - - - - - - - - - YppG k141_20803_2 1116375.VEJY3_23521 1.01e-186 522.0 COG0834@1|root,COG0834@2|Bacteria,1MWIK@1224|Proteobacteria,1RPBR@1236|Gammaproteobacteria,1XV4Y@135623|Vibrionales 135623|Vibrionales ET Bacterial periplasmic substrate-binding proteins VPA1512 - - - - - - - - - - - SBP_bac_3 k141_13973_1 586413.CCDL010000001_gene962 1.7e-12 66.6 COG4948@1|root,COG4948@2|Bacteria,1TQMS@1239|Firmicutes,4HCY5@91061|Bacilli,23IPE@182709|Oceanobacillus 91061|Bacilli M Methylaspartate ammonia-lyase C-terminus ykfB - 5.1.1.20 ko:K19802 - - R10938 RC03309 ko00000,ko01000 - - - MR_MLE_C,MR_MLE_N k141_13973_2 218284.CCDN010000001_gene1589 2.92e-149 427.0 COG1619@1|root,COG1619@2|Bacteria,1TRBB@1239|Firmicutes,4HAWT@91061|Bacilli,1ZC09@1386|Bacillus 91061|Bacilli V proteins, homologs of microcin C7 resistance protein MccF ykfA - 3.4.17.13 ko:K01297 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_S66 k141_27862_1 493475.GARC_4043 3.64e-56 187.0 COG0412@1|root,COG0412@2|Bacteria 2|Bacteria Q carboxymethylenebutenolidase activity M1-673 - 3.1.1.45 ko:K01061,ko:K07017 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 - R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222 RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 - - - DLH k141_27862_2 493475.GARC_4044 6.44e-219 620.0 COG1292@1|root,COG1292@2|Bacteria,1MV0K@1224|Proteobacteria,1RP3E@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Belongs to the BCCT transporter (TC 2.A.15) family - - - ko:K03451 - - - - ko00000 2.A.15 - - BCCT k141_23730_1 1307436.PBF_11397 1.71e-133 381.0 COG0745@1|root,COG0745@2|Bacteria,1TR32@1239|Firmicutes,4HAUJ@91061|Bacilli,1ZCP0@1386|Bacillus 91061|Bacilli T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain graR - - ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 M00469,M00725,M00726,M00730,M00733,M00738 - - ko00000,ko00001,ko00002,ko01504,ko02022 - - - Response_reg,Trans_reg_C k141_1021_1 1453501.JELR01000002_gene1028 2.39e-33 120.0 COG1585@1|root,COG1585@2|Bacteria,1RG29@1224|Proteobacteria,1S7HI@1236|Gammaproteobacteria,467KK@72275|Alteromonadaceae 1236|Gammaproteobacteria OU Protein of unknown function (DUF1449) - - - - - - - - - - - - DUF1449 k141_1021_3 1453501.JELR01000002_gene1030 6.38e-38 132.0 2FEBB@1|root,346B2@2|Bacteria,1P137@1224|Proteobacteria,1SRAD@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_5750_1 1453501.JELR01000002_gene152 0.0 1047.0 COG3164@1|root,COG3164@2|Bacteria,1MXWF@1224|Proteobacteria,1RNUK@1236|Gammaproteobacteria,464CY@72275|Alteromonadaceae 1236|Gammaproteobacteria S membrane yhdP GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0042597,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - - - - - - - - - - AsmA_2,DUF3971 k141_5750_3 1453501.JELR01000002_gene151 6.16e-152 432.0 28NHW@1|root,2ZBJG@2|Bacteria,1RBJB@1224|Proteobacteria,1S31B@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_32901_1 626887.J057_15155 4.27e-97 292.0 COG1319@1|root,COG1319@2|Bacteria,1MVJS@1224|Proteobacteria,1RY6A@1236|Gammaproteobacteria,465GM@72275|Alteromonadaceae 1236|Gammaproteobacteria C Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM yagS GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.17.1.4 ko:K11178 ko00230,ko01100,ko01120,map00230,map01100,map01120 M00546 R01768,R02103 RC00143 ko00000,ko00001,ko00002,ko01000 - - - CO_deh_flav_C,FAD_binding_5 k141_31524_1 218284.CCDN010000002_gene1992 1.57e-249 692.0 COG0138@1|root,COG0138@2|Bacteria,1TPQ5@1239|Firmicutes,4H9YY@91061|Bacilli,1ZD5E@1386|Bacillus 91061|Bacilli F Bifunctional purine biosynthesis protein PurH purH - 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 - - - AICARFT_IMPCHas,MGS k141_6993_2 262543.Exig_2191 1.86e-279 772.0 COG0753@1|root,COG0753@2|Bacteria,1TPPV@1239|Firmicutes,4H9XQ@91061|Bacilli,3WFA4@539002|Bacillales incertae sedis 91061|Bacilli P Belongs to the catalase family kat GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070887,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1990748 1.11.1.6 ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 M00532 R00009,R00602,R02670 RC00034,RC00767,RC02141,RC02755 ko00000,ko00001,ko00002,ko01000 - - - Catalase,Catalase-rel k141_24708_1 218284.CCDN010000004_gene3045 4.33e-118 345.0 COG1181@1|root,COG1181@2|Bacteria,1TP2Y@1239|Firmicutes,4H9KB@91061|Bacilli,1ZDA3@1386|Bacillus 91061|Bacilli F Belongs to the D-alanine--D-alanine ligase family ddl - 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Dala_Dala_lig_C,Dala_Dala_lig_N k141_22394_1 42565.FP66_08670 2.17e-138 408.0 COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RQIN@1236|Gammaproteobacteria,1XHAU@135619|Oceanospirillales 135619|Oceanospirillales T Signal transduction histidine kinase - - 2.7.13.3 ko:K10125 ko02020,map02020 M00504 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS,PAS_9,dCache_1 k141_9386_1 1116375.VEJY3_20406 4.67e-185 519.0 COG0479@1|root,COG0479@2|Bacteria,1QVWG@1224|Proteobacteria,1RNMQ@1236|Gammaproteobacteria,1XSXJ@135623|Vibrionales 135623|Vibrionales C 4Fe-4S dicluster domain asrA - - - - - - - - - - - Fer4_22 k141_9386_3 1116375.VEJY3_20396 0.0 1483.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,1RP3T@1236|Gammaproteobacteria,1Y3CC@135623|Vibrionales 135623|Vibrionales H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate - - 2.7.9.2 ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 M00173,M00374 R00199 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - PEP-utilizers,PEP-utilizers_C,PPDK_N k141_9386_4 1116375.VEJY3_20391 1.72e-47 152.0 COG0236@1|root,COG0236@2|Bacteria,1NHIC@1224|Proteobacteria,1SGKM@1236|Gammaproteobacteria 1236|Gammaproteobacteria IQ Phosphopantetheine attachment site - - - - - - - - - - - - PP-binding k141_23731_1 1121938.AUDY01000002_gene485 4.34e-109 323.0 28I0M@1|root,2Z85B@2|Bacteria,1TTBC@1239|Firmicutes,4HENN@91061|Bacilli,3NFZZ@45667|Halobacillus 91061|Bacilli S Protein of unknown function (DUF3231) - - - - - - - - - - - - DUF3231 k141_11751_1 218284.CCDN010000007_gene4015 5.7e-130 374.0 COG0739@1|root,COG0739@2|Bacteria,1V7CU@1239|Firmicutes,4HCZJ@91061|Bacilli,1ZC61@1386|Bacillus 91061|Bacilli M COG0739 Membrane proteins related to metalloendopeptidases spoIIQ GO:0005575,GO:0005623,GO:0042601,GO:0042763,GO:0044464 - ko:K06386 - - - - ko00000 1.A.34.1.1 - - Peptidase_M23 k141_34199_1 546271.Selsp_1699 2.3e-86 273.0 COG1157@1|root,COG1157@2|Bacteria,1TP0R@1239|Firmicutes,4H2V3@909932|Negativicutes 909932|Negativicutes N Flagellar protein export ATPase FliI fliI - 3.6.3.14 ko:K02412 ko02040,map02040 - - - ko00000,ko00001,ko01000,ko02035,ko02044 3.A.6.2,3.A.6.3 - - ATP-synt_ab,ATP-synt_ab_N k141_34199_4 903818.KI912268_gene3446 1.17e-53 194.0 COG1766@1|root,COG1766@2|Bacteria,3Y2HU@57723|Acidobacteria 57723|Acidobacteria N The M ring may be actively involved in energy transduction - - - ko:K02409 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 - - YscJ_FliF,YscJ_FliF_C k141_34199_5 635013.TherJR_1543 2.1e-16 75.1 COG1677@1|root,COG1677@2|Bacteria,1VEEY@1239|Firmicutes,24R4F@186801|Clostridia,262TX@186807|Peptococcaceae 186801|Clostridia N Flagellar hook-basal body complex protein FliE fliE - - ko:K02408 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FliE k141_34199_6 683083.C414_000080184 5.9e-17 80.1 COG1558@1|root,COG1558@2|Bacteria,1RHI3@1224|Proteobacteria,42TPI@68525|delta/epsilon subdivisions,2YP1Q@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria N Belongs to the flagella basal body rod proteins family flgC - - ko:K02388 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C k141_34199_8 1101195.Meth11DRAFT_1131 6.93e-16 77.0 COG1706@1|root,COG1706@2|Bacteria,1MVKW@1224|Proteobacteria,2VJAZ@28216|Betaproteobacteria,2KKTZ@206350|Nitrosomonadales 28216|Betaproteobacteria N Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation - - - ko:K02394 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FlgI k141_37594_1 218284.CCDN010000006_gene3609 1.34e-62 212.0 COG0557@1|root,COG0557@2|Bacteria,1TQ1G@1239|Firmicutes,4HBBH@91061|Bacilli,1ZBDP@1386|Bacillus 91061|Bacilli K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs rnr - - ko:K12573 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03016,ko03019 - - - OB_RNB,RNB,S1 k141_19991_1 1453501.JELR01000002_gene814 5.04e-59 206.0 COG0553@1|root,COG0553@2|Bacteria,1MV6M@1224|Proteobacteria,1RQ34@1236|Gammaproteobacteria,465QU@72275|Alteromonadaceae 1236|Gammaproteobacteria KL SNF2 family N-terminal domain - - - - - - - - - - - - Helicase_C,SNF2_N,SWIM k141_6994_1 1123237.Salmuc_02668 1.54e-06 48.1 COG3090@1|root,COG3090@2|Bacteria,1RK5Q@1224|Proteobacteria,2UAJ4@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Tripartite ATP-independent periplasmic transporters, DctQ component - - - - - - - - - - - - DctQ k141_6994_2 1123237.Salmuc_02669 4.34e-93 284.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2TQNK@28211|Alphaproteobacteria 28211|Alphaproteobacteria G COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - - - - - - - - - - DctM k141_1022_3 1219076.N646_1931 1.74e-21 86.7 COG3029@1|root,COG3029@2|Bacteria,1MZ4C@1224|Proteobacteria,1SC0P@1236|Gammaproteobacteria,1XXFQ@135623|Vibrionales 135623|Vibrionales C Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane frdC GO:0000104,GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0016627,GO:0044237,GO:0045333,GO:0055114 - ko:K00246 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00150,M00173 R02164 RC00045 ko00000,ko00001,ko00002 - - - Fumarate_red_C k141_5751_1 42565.FP66_00355 1.39e-120 348.0 COG1737@1|root,COG1737@2|Bacteria,1R6J5@1224|Proteobacteria,1RQ8A@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator - - - - - - - - - - - - HTH_6,SIS k141_19018_1 1453501.JELR01000002_gene496 1.26e-92 285.0 COG0527@1|root,COG0527@2|Bacteria,1MVSI@1224|Proteobacteria,1RQ37@1236|Gammaproteobacteria,4658P@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0527 Aspartokinases lysC GO:0003674,GO:0003824,GO:0004072,GO:0006082,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019491,GO:0019752,GO:0032787,GO:0042399,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,ACT_7 k141_16325_1 1453501.JELR01000001_gene2296 1.51e-145 421.0 COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,1RN93@1236|Gammaproteobacteria,464G4@72275|Alteromonadaceae 1236|Gammaproteobacteria F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily purB - 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 - - - ASL_C,Lyase_1 k141_10460_2 1042377.AFPJ01000012_gene1349 1.74e-73 240.0 COG4772@1|root,COG4772@2|Bacteria,1MWDG@1224|Proteobacteria,1RQA5@1236|Gammaproteobacteria,464IF@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG4772 Outer membrane receptor for Fe3 -dicitrate fecA - - ko:K16091 - - - - ko00000,ko02000 1.B.14.1.14 - - Plug,TonB_dep_Rec k141_24709_1 1340434.AXVA01000007_gene5135 6.32e-31 112.0 2E849@1|root,332I1@2|Bacteria,1VXYE@1239|Firmicutes,4HXSS@91061|Bacilli,1ZH94@1386|Bacillus 91061|Bacilli L LAGLIDADG-like domain - - - - - - - - - - - - LAGLIDADG_3 k141_11752_1 997296.PB1_09567 1.02e-97 291.0 COG1481@1|root,COG1481@2|Bacteria,1TP2X@1239|Firmicutes,4HB4H@91061|Bacilli,1ZBKY@1386|Bacillus 91061|Bacilli K May be required for sporulation whiA GO:0008150,GO:0043937,GO:0050789,GO:0050793,GO:0065007 - ko:K09762 - - - - ko00000 - - - HTH_WhiA,LAGLIDADG_WhiA,WhiA_N k141_22395_2 1117647.M5M_09025 2.72e-112 348.0 COG1629@1|root,COG4771@2|Bacteria,1MVFB@1224|Proteobacteria,1RNMS@1236|Gammaproteobacteria,1J4QU@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec k141_9388_1 218284.CCDN010000011_gene4424 1.18e-123 365.0 COG0519@1|root,COG0519@2|Bacteria,1TPG8@1239|Firmicutes,4HA7Q@91061|Bacilli,1ZB6Z@1386|Bacillus 91061|Bacilli F Catalyzes the synthesis of GMP from XMP guaA GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase,GMP_synt_C,NAD_synthase k141_1023_1 240302.BN982_03159 5.3e-193 541.0 COG1902@1|root,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,4HDIY@91061|Bacilli,3NDDY@45667|Halobacillus 91061|Bacilli C NADH:flavin oxidoreductase / NADH oxidase family - - - - - - - - - - - - Oxidored_FMN k141_30378_1 1379698.RBG1_1C00001G0370 1.35e-22 102.0 COG0616@1|root,COG0616@2|Bacteria,2NNKU@2323|unclassified Bacteria 2|Bacteria OU Peptidase family S49 sppA - - ko:K04773 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S49 k141_37620_1 984262.SGRA_0741 1.46e-24 103.0 COG1249@1|root,COG1249@2|Bacteria,4NDVC@976|Bacteroidetes,1IQG6@117747|Sphingobacteriia 976|Bacteroidetes C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3) lpdA - 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyr_redox_2,Pyr_redox_dim k141_37620_2 861299.J421_2661 1.76e-06 50.4 COG0321@1|root,COG0321@2|Bacteria,1ZTM1@142182|Gemmatimonadetes 142182|Gemmatimonadetes H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate lipB - 2.3.1.181 ko:K03801 ko00785,ko01100,map00785,map01100 - R07766,R07769 RC00039,RC00992,RC02867 ko00000,ko00001,ko01000 - - - BPL_LplA_LipB k141_4411_1 1453501.JELR01000002_gene1224 4.82e-283 785.0 COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,464J7@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0405 Gamma-glutamyltransferase ggt - 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept k141_31547_1 218284.CCDN010000001_gene130 1.15e-105 311.0 COG0109@1|root,COG0109@2|Bacteria,1TPS1@1239|Firmicutes,4HBJT@91061|Bacilli,1ZCJT@1386|Bacillus 91061|Bacilli O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group ctaB GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 M00154 R07411 RC01786 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 - - iSB619.SA_RS05465 UbiA k141_23764_2 585531.HMPREF0063_10480 4.83e-11 65.9 COG0823@1|root,COG1404@1|root,COG0823@2|Bacteria,COG1404@2|Bacteria,2IC0F@201174|Actinobacteria 201174|Actinobacteria U Involved in the tonB-independent uptake of proteins - - - - - - - - - - - - PD40 k141_22429_1 1116375.VEJY3_17341 3.06e-157 447.0 COG1816@1|root,COG1816@2|Bacteria,1MWBV@1224|Proteobacteria,1RNVI@1236|Gammaproteobacteria,1XU77@135623|Vibrionales 135623|Vibrionales F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism - - 3.5.4.2 ko:K21053 ko00230,ko01100,map00230,map01100 - R01244 RC00477 ko00000,ko00001,ko01000 - - - A_deaminase k141_22429_2 1116375.VEJY3_17336 5.63e-100 291.0 COG0678@1|root,COG0678@2|Bacteria,1MU0H@1224|Proteobacteria,1RRFB@1236|Gammaproteobacteria,1XUW9@135623|Vibrionales 135623|Vibrionales O Redoxin - - - - - - - - - - - - Redoxin k141_22429_3 672.VV93_v1c14240 3.34e-72 241.0 COG5640@1|root,COG5640@2|Bacteria,1QJHF@1224|Proteobacteria,1THHB@1236|Gammaproteobacteria,1XVVF@135623|Vibrionales 135623|Vibrionales M Trypsin-like serine protease - - - - - - - - - - - - Trypsin k141_22429_4 223926.28809664 5.75e-238 659.0 COG1686@1|root,COG1686@2|Bacteria,1MUU7@1224|Proteobacteria,1RMJA@1236|Gammaproteobacteria,1XSFX@135623|Vibrionales 135623|Vibrionales M Belongs to the peptidase S11 family - - 3.4.16.4 ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - PBP5_C,Peptidase_S11 k141_22429_5 1116375.VEJY3_17326 2.43e-205 568.0 COG0625@1|root,COG0625@2|Bacteria,1MUN3@1224|Proteobacteria,1RMF7@1236|Gammaproteobacteria,1XTEP@135623|Vibrionales 135623|Vibrionales O Glutathione S-transferase - - - ko:K11209 - - - - ko00000,ko01000 - - - GST_C_2,GST_N,GST_N_2 k141_22429_6 1116375.VEJY3_17321 3.34e-155 437.0 COG1028@1|root,COG1028@2|Bacteria,1N907@1224|Proteobacteria,1S0GV@1236|Gammaproteobacteria,1XTGE@135623|Vibrionales 135623|Vibrionales IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 k141_22429_7 1116375.VEJY3_17316 3.93e-141 400.0 COG3806@1|root,COG3806@2|Bacteria,1R52I@1224|Proteobacteria,1RNI5@1236|Gammaproteobacteria,1XVGP@135623|Vibrionales 135623|Vibrionales T ChrR Cupin-like domain - - - - - - - - - - - - Cupin_7 k141_22429_8 1219076.N646_3821 6.85e-44 143.0 COG2841@1|root,COG2841@2|Bacteria,1NDHE@1224|Proteobacteria,1SDIQ@1236|Gammaproteobacteria,1XZ2Y@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria VPA0402 - - ko:K09794 - - - - ko00000 - - - DUF465 k141_22429_9 223926.28808563 2.36e-127 374.0 2FGUU@1|root,348Q5@2|Bacteria,1P1UI@1224|Proteobacteria,1SSBF@1236|Gammaproteobacteria,1XWDV@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_22429_10 1116375.VEJY3_17296 4.51e-147 416.0 COG0095@1|root,COG0095@2|Bacteria,1MZGC@1224|Proteobacteria,1RN92@1236|Gammaproteobacteria,1XV7Y@135623|Vibrionales 135623|Vibrionales H Lipoate-protein ligase A - - - - - - - - - - - - - k141_22429_11 1116375.VEJY3_22496 0.0 1036.0 COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria,1XTXC@135623|Vibrionales 135623|Vibrionales V COG1132 ABC-type multidrug transport system, ATPase and permease components - - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran k141_22429_12 1116375.VEJY3_17291 2.3e-94 275.0 COG0346@1|root,COG0346@2|Bacteria,1RF7M@1224|Proteobacteria,1S3TZ@1236|Gammaproteobacteria,1XX6E@135623|Vibrionales 135623|Vibrionales E COG0346 Lactoylglutathione lyase and related lyases - - - - - - - - - - - - Glyoxalase,Glyoxalase_4 k141_22429_13 223926.28808556 8.36e-269 745.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1XSNZ@135623|Vibrionales 135623|Vibrionales F DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA rhlE - 3.6.4.13 ko:K11927 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - DEAD,Helicase_C k141_1066_1 380358.XALC_1197 1.76e-98 300.0 COG0477@1|root,COG0477@2|Bacteria,1NS3F@1224|Proteobacteria,1T1MQ@1236|Gammaproteobacteria,1X2ZE@135614|Xanthomonadales 135614|Xanthomonadales EGP Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family xylE - - ko:K08139 ko04113,map04113 - - - ko00000,ko00001,ko02000 2.A.1.1 - - Sugar_tr k141_36403_2 218284.CCDN010000001_gene1349 5.06e-56 177.0 COG4633@1|root,COG4633@2|Bacteria,1V9CQ@1239|Firmicutes,4HJCI@91061|Bacilli,1ZF9J@1386|Bacillus 91061|Bacilli S Cupredoxin-like domain - - - - - - - - - - - - Cupredoxin_1 k141_29406_1 1131730.BAVI_22658 1.88e-165 475.0 COG3182@1|root,COG3182@2|Bacteria,1TSD4@1239|Firmicutes,4HDAS@91061|Bacilli,1ZCZS@1386|Bacillus 91061|Bacilli S PepSY-associated TM region - - - - - - - - - - - - PepSY,PepSY_TM k141_9419_1 1116375.VEJY3_00780 2.21e-156 441.0 COG1196@1|root,COG1196@2|Bacteria,1NGHR@1224|Proteobacteria,1RQW7@1236|Gammaproteobacteria,1XU9S@135623|Vibrionales 135623|Vibrionales D Protein of unknown function (DUF3450) - - - - - - - - - - - - DUF3450 k141_9419_2 223926.28805148 3.83e-273 753.0 COG0811@1|root,COG0811@2|Bacteria,1MX5J@1224|Proteobacteria,1RMSA@1236|Gammaproteobacteria,1XU3B@135623|Vibrionales 135623|Vibrionales U MotA/TolQ/ExbB proton channel family - - - ko:K03561 - - - - ko00000,ko02000 1.A.30.2.1 - - MotA_ExbB k141_15113_1 218284.CCDN010000002_gene2402 1.33e-117 357.0 COG0376@1|root,COG0376@2|Bacteria,1TQDA@1239|Firmicutes,4HBZ5@91061|Bacilli,1ZD07@1386|Bacillus 91061|Bacilli P Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity katG - 1.11.1.21 ko:K03782 ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110 - R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906 RC00034,RC00213,RC00767,RC02141 ko00000,ko00001,ko01000 - - - peroxidase k141_35500_1 1231057.AMGD01000006_gene2682 8.49e-06 46.6 2AHVT@1|root,3188J@2|Bacteria,1V8V5@1239|Firmicutes,4HRM7@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - k141_17412_1 1116375.VEJY3_23701 0.0 917.0 COG0296@1|root,COG0296@2|Bacteria,1QTVN@1224|Proteobacteria,1RQSK@1236|Gammaproteobacteria,1XU7M@135623|Vibrionales 135623|Vibrionales G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position glgB GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901576 2.4.1.18 ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02110 - ko00000,ko00001,ko00002,ko01000,ko04147 - CBM48,GH13 - Alpha-amylase,Alpha-amylase_C,CBM_48 k141_17412_2 1116375.VEJY3_23706 0.0 1419.0 COG1640@1|root,COG1640@2|Bacteria,1QTVJ@1224|Proteobacteria,1RMJW@1236|Gammaproteobacteria,1XTQ7@135623|Vibrionales 135623|Vibrionales G 4-alpha-glucanotransferase malQ - 2.4.1.25 ko:K00705 ko00500,ko01100,map00500,map01100 - R05196 RC00049 ko00000,ko00001,ko01000 - GH77 - Glyco_hydro_77 k141_17412_3 1116375.VEJY3_23711 0.0 1593.0 COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,1RN8P@1236|Gammaproteobacteria,1XSRI@135623|Vibrionales 135623|Vibrionales G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties malP - 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 - R02111 - ko00000,ko00001,ko01000 - GT35 - Phosphorylase k141_17412_4 1116375.VEJY3_23716 0.0 1732.0 COG2909@1|root,COG2909@2|Bacteria,1MVZZ@1224|Proteobacteria,1RN29@1236|Gammaproteobacteria,1XUE3@135623|Vibrionales 135623|Vibrionales K Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides. Binds and recognizes a DNA motif (called the malT box) 5'-GGA TG GA-3' malT GO:0003674,GO:0003700,GO:0005975,GO:0006355,GO:0008150,GO:0008152,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044238,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 - ko:K03556 - - - - ko00000,ko03000 - - - GerE k141_17412_5 1116375.VEJY3_23721 9.02e-192 535.0 COG2035@1|root,COG2035@2|Bacteria,1MXVI@1224|Proteobacteria,1RN4B@1236|Gammaproteobacteria,1XSHN@135623|Vibrionales 135623|Vibrionales S Domain of unknown function (DUF368) - - - ko:K08974 - - - - ko00000 - - - DUF368 k141_17412_6 1116375.VEJY3_23726 2.78e-81 242.0 2DQHM@1|root,336XW@2|Bacteria,1N98A@1224|Proteobacteria,1SE80@1236|Gammaproteobacteria,1XY0J@135623|Vibrionales 135623|Vibrionales - - VPA1625 - - - - - - - - - - - - k141_17412_7 1116375.VEJY3_23731 4.41e-128 365.0 COG1999@1|root,COG1999@2|Bacteria,1RHJ8@1224|Proteobacteria,1SYIQ@1236|Gammaproteobacteria,1XT7R@135623|Vibrionales 135623|Vibrionales S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems - - - ko:K07152 - - - - ko00000,ko03029 - - - SCO1-SenC k141_17412_8 1116375.VEJY3_23736 2.73e-55 173.0 COG1264@1|root,COG1264@2|Bacteria,1QTH9@1224|Proteobacteria,1TIIU@1236|Gammaproteobacteria,1XZ7G@135623|Vibrionales 135623|Vibrionales G COG1264 Phosphotransferase system IIB components - - 2.7.1.199 ko:K02778 ko00010,ko00520,ko02060,ko05111,map00010,map00520,map02060,map05111 M00265 R02738 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.1 - - PTS_EIIB k141_17412_9 1116375.VEJY3_23741 5.58e-218 606.0 COG1162@1|root,COG1162@2|Bacteria,1MUEF@1224|Proteobacteria,1RMMB@1236|Gammaproteobacteria,1XSIW@135623|Vibrionales 135623|Vibrionales S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit rsgA2 - 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 - R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 - - - RsgA_GTPase k141_17412_10 1116375.VEJY3_23746 1.34e-263 725.0 COG3633@1|root,COG3633@2|Bacteria,1MXE1@1224|Proteobacteria,1RP9B@1236|Gammaproteobacteria,1XSMF@135623|Vibrionales 135623|Vibrionales E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) sstT GO:0003674,GO:0005215,GO:0005310,GO:0005342,GO:0005343,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0006820,GO:0006835,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015077,GO:0015081,GO:0015291,GO:0015293,GO:0015294,GO:0015318,GO:0015370,GO:0015672,GO:0015711,GO:0015849,GO:0017153,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0035725,GO:0046873,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0098655,GO:0098656,GO:0098660,GO:0098662,GO:1903825,GO:1905039 - ko:K07862 - - - - ko00000,ko02000 2.A.23.4 - - SDF k141_17412_11 1219076.N646_3351 1.89e-195 543.0 COG2240@1|root,COG2240@2|Bacteria,1MVC9@1224|Proteobacteria,1RMIE@1236|Gammaproteobacteria,1XSHI@135623|Vibrionales 135623|Vibrionales H Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP pdxY - 2.7.1.35 ko:K00868 ko00750,ko01100,map00750,map01100 - R00174,R01909,R02493 RC00002,RC00017 ko00000,ko00001,ko01000 - - - Phos_pyr_kin k141_17412_12 1116375.VEJY3_23756 1.43e-209 588.0 COG0790@1|root,COG0790@2|Bacteria,1NFG6@1224|Proteobacteria,1SYKC@1236|Gammaproteobacteria,1Y2TA@135623|Vibrionales 135623|Vibrionales S Sel1-like repeats. - - - - - - - - - - - - Sel1 k141_17412_13 1116375.VEJY3_23761 0.0 2286.0 COG1523@1|root,COG1523@2|Bacteria,1MU19@1224|Proteobacteria,1RP6F@1236|Gammaproteobacteria,1XT7C@135623|Vibrionales 135623|Vibrionales G Belongs to the glycosyl hydrolase 13 family - - 3.2.1.41 ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 - R02111 - ko00000,ko00001,ko01000 - CBM48,GH13 - Alpha-amylase,CBM_48,DUF3372,PUD k141_16341_2 1116375.VEJY3_17216 4.28e-105 304.0 COG1522@1|root,COG1522@2|Bacteria,1RDPM@1224|Proteobacteria,1S4P8@1236|Gammaproteobacteria,1Y2XT@135623|Vibrionales 135623|Vibrionales K AsnC-type helix-turn-helix domain - - - ko:K15782 - - - - ko00000,ko03000 - - - AsnC_trans_reg,HTH_24 k141_7030_1 218284.CCDN010000001_gene1868 2.46e-42 148.0 COG1744@1|root,COG1744@2|Bacteria,1TPEU@1239|Firmicutes,4HANH@91061|Bacilli,1ZBS3@1386|Bacillus 91061|Bacilli S ABC-type transport system, periplasmic component surface lipoprotein tcsA - - ko:K02058,ko:K07335 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - Bmp k141_29407_1 1123401.JHYQ01000016_gene3046 8.95e-32 129.0 COG3534@1|root,COG4409@1|root,COG4733@1|root,COG3534@2|Bacteria,COG4409@2|Bacteria,COG4733@2|Bacteria,1R1WB@1224|Proteobacteria,1T5C7@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Cellulase N-terminal ig-like domain - - - - - - - - - - - - CelD_N,Glyco_hydro_9 k141_9420_1 1279017.AQYJ01000024_gene1096 3.53e-67 206.0 COG0494@1|root,COG0494@2|Bacteria,1RCZM@1224|Proteobacteria,1RS3S@1236|Gammaproteobacteria,467U6@72275|Alteromonadaceae 1236|Gammaproteobacteria L Belongs to the Nudix hydrolase family mutT GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008413,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017110,GO:0030145,GO:0033554,GO:0034641,GO:0035539,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044715,GO:0044716,GO:0046483,GO:0046872,GO:0046914,GO:0047429,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - iE2348C_1286.E2348C_0104,iSDY_1059.SDY_0129 NUDIX,NUDIX_4,TMP-TENI k141_1955_1 501479.ACNW01000102_gene778 5.66e-101 304.0 COG1364@1|root,COG1364@2|Bacteria,1MU0T@1224|Proteobacteria,2TS98@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate argJ GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R00259,R02282 RC00004,RC00064 ko00000,ko00001,ko00002,ko01000 - - - ArgJ k141_5772_2 1453501.JELR01000002_gene145 1.93e-61 193.0 COG1057@1|root,COG1057@2|Bacteria,1RD0J@1224|Proteobacteria,1RP00@1236|Gammaproteobacteria,46745@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) nadD GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034355,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043094,GO:0043173,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18,3.5.4.4 ko:K00969,ko:K01488 ko00230,ko00760,ko01100,ko05340,map00230,map00760,map01100,map05340 M00115 R00137,R01560,R02556,R03005 RC00002,RC00477 ko00000,ko00001,ko00002,ko01000 - - iECUMN_1333.ECUMN_0733,iJN746.PP_4810,iPC815.YPO2607,iSbBS512_1146.SbBS512_E0612 CTP_transf_like k141_28037_1 218284.CCDN010000003_gene2977 6e-212 585.0 28HCB@1|root,2Z7P7@2|Bacteria,1TNZK@1239|Firmicutes,4HBET@91061|Bacilli,1ZCTC@1386|Bacillus 91061|Bacilli S peptidase yabG GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0031160,GO:0043591,GO:0043593,GO:0044426,GO:0044462,GO:0044464,GO:0071944 - ko:K06436 - - - - ko00000 - - - Peptidase_U57 k141_8123_2 1114856.C496_19275 1.69e-47 162.0 arCOG14740@1|root,arCOG14740@2157|Archaea,2Y46U@28890|Euryarchaeota 28890|Euryarchaeota S TupA-like ATPgrasp - - - - - - - - - - - - ATPgrasp_TupA k141_2292_1 42565.FP66_12680 4.02e-93 274.0 COG4668@1|root,COG4668@2|Bacteria 2|Bacteria G phosphoenolpyruvate-dependent sugar phosphotransferase system fruB GO:0003674,GO:0003824,GO:0005215,GO:0005353,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0008645,GO:0008982,GO:0009401,GO:0015144,GO:0015145,GO:0015149,GO:0015749,GO:0015755,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0019897,GO:0019898,GO:0022804,GO:0022857,GO:0022877,GO:0032445,GO:0034219,GO:0044425,GO:0044459,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563 2.7.1.202,2.7.3.9 ko:K02768,ko:K02769,ko:K02770,ko:K08483,ko:K11183,ko:K11189 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1,8.A.7 - iSBO_1134.SBO_2155,iSbBS512_1146.SbBS512_E0794 PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C,PTS-HPr,PTS_EIIA_2 k141_2292_2 42565.FP66_12685 1.42e-15 74.7 COG1609@1|root,COG1609@2|Bacteria,1MXQ1@1224|Proteobacteria,1RNR1@1236|Gammaproteobacteria,1XPAN@135619|Oceanospirillales 135619|Oceanospirillales K helix_turn _helix lactose operon repressor - - - ko:K03435 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_1 k141_16613_1 1294265.JCM21738_5456 1.24e-75 232.0 COG3069@1|root,COG3069@2|Bacteria,1TQ99@1239|Firmicutes,4H9Q2@91061|Bacilli,1ZCNB@1386|Bacillus 91061|Bacilli C membrane yhfA - - - - - - - - - - - - k141_37922_1 218284.CCDN010000002_gene2098 8.68e-129 380.0 COG1721@1|root,COG1721@2|Bacteria,1V51Y@1239|Firmicutes,4HHN0@91061|Bacilli,1ZN11@1386|Bacillus 91061|Bacilli S Protein of unknown function DUF58 - - - - - - - - - - - - DUF58 k141_16614_1 644282.Deba_2661 0.000135 45.8 COG2210@1|root,COG2210@2|Bacteria,1RDUG@1224|Proteobacteria,42VFB@68525|delta/epsilon subdivisions,2WRRQ@28221|Deltaproteobacteria 28221|Deltaproteobacteria S DsrE/DsrF/DrsH-like family - - - - - - - - - - - - DrsE_2 k141_16614_2 1108045.GORHZ_143_00030 5.65e-09 55.1 COG0640@1|root,COG0640@2|Bacteria,2IKPW@201174|Actinobacteria 201174|Actinobacteria K Transcriptional regulator, arsR family - - - - - - - - - - - - HTH_5 k141_28341_1 114615.BRADO4380 8.33e-15 73.9 COG3501@1|root,COG3501@2|Bacteria,1R540@1224|Proteobacteria,2V65Q@28211|Alphaproteobacteria,3K5JD@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Baseplate assembly protein - - - - - - - - - - - - - k141_28341_3 338966.Ppro_1815 4.4e-22 91.7 COG3628@1|root,COG3628@2|Bacteria,1N039@1224|Proteobacteria,43DQ3@68525|delta/epsilon subdivisions,2WR64@28221|Deltaproteobacteria,43VVC@69541|Desulfuromonadales 28221|Deltaproteobacteria S Gene 25-like lysozyme - - - ko:K06903 - - - - ko00000 - - - GPW_gp25 k141_17809_1 1173264.KI913949_gene4244 3.67e-16 81.3 2E7W0@1|root,332AS@2|Bacteria,1G6TE@1117|Cyanobacteria,1HCEI@1150|Oscillatoriales 1117|Cyanobacteria - - - - - - - - - - - - - - - k141_8125_1 1348908.KI518634_gene1347 3.21e-35 134.0 COG0840@1|root,COG0840@2|Bacteria,1TRTV@1239|Firmicutes,4H9M1@91061|Bacilli,1ZBCT@1386|Bacillus 91061|Bacilli NT chemotaxis protein hemAT - - ko:K06595 - - - - ko00000,ko02035 - - - MCPsignal,Protoglobin k141_21306_1 218284.CCDN010000003_gene3011 7.6e-109 320.0 COG0115@1|root,COG0115@2|Bacteria,1TSIP@1239|Firmicutes,4HC7K@91061|Bacilli,1ZCRC@1386|Bacillus 91061|Bacilli EH 4-amino-4-deoxychorismate lyase pabC - 4.1.3.38 ko:K02619 ko00790,map00790 - R05553 RC01843,RC02148 ko00000,ko00001,ko01000 - - - Aminotran_4 k141_21306_2 218284.CCDN010000003_gene3010 9.75e-117 336.0 COG0512@1|root,COG0512@2|Bacteria,1TT9R@1239|Firmicutes,4H9XP@91061|Bacilli,1ZBB7@1386|Bacillus 91061|Bacilli EH Anthranilate synthase pabA GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006575,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009108,GO:0009308,GO:0009309,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042398,GO:0042401,GO:0042430,GO:0042435,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 2.6.1.85 ko:K01664 ko00790,map00790 - R01716 RC00010,RC01418 ko00000,ko00001,ko01000 - - iYO844.BSU00750 GATase k141_28342_1 1112214.AHIS01000002_gene1823 2.44e-26 109.0 COG0726@1|root,COG0726@2|Bacteria,1RFCG@1224|Proteobacteria,2U92E@28211|Alphaproteobacteria,2K4B9@204457|Sphingomonadales 204457|Sphingomonadales G Polysaccharide deacetylase - - - - - - - - - - - - Polysacc_deac_1 k141_36609_2 1219076.N646_3492 3.02e-179 502.0 28IGK@1|root,2Z8I1@2|Bacteria,1RAH7@1224|Proteobacteria,1RPTY@1236|Gammaproteobacteria,1XTA2@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_37923_1 330214.NIDE1323 1.93e-82 249.0 COG0094@1|root,COG0094@2|Bacteria,3J0HN@40117|Nitrospirae 40117|Nitrospirae J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits rplE - - ko:K02931 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L5,Ribosomal_L5_C k141_34477_1 1279017.AQYJ01000026_gene293 7.72e-120 353.0 COG0354@1|root,COG0354@2|Bacteria,1N852@1224|Proteobacteria,1RPWB@1236|Gammaproteobacteria,466QJ@72275|Alteromonadaceae 1236|Gammaproteobacteria S aminomethyltransferase related to GcvT ygfZ GO:0003674,GO:0005488,GO:0005542,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0019842,GO:0022607,GO:0031163,GO:0031406,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0071840,GO:0072341,GO:0097159,GO:1901363 - ko:K06980 - - - - ko00000,ko03016 - - - GCV_T,GCV_T_C k141_28343_1 1089550.ATTH01000001_gene660 4.39e-19 91.3 COG2027@1|root,COG2027@2|Bacteria,4NGIQ@976|Bacteroidetes,1FIVK@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes M D-Ala-D-Ala carboxypeptidase 3 (S13) family - - 3.4.16.4 ko:K07259 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - Peptidase_S13 k141_33225_2 1279017.AQYJ01000023_gene3163 2.07e-46 151.0 COG0713@1|root,COG0713@2|Bacteria,1RH0S@1224|Proteobacteria,1S6FN@1236|Gammaproteobacteria,468MA@72275|Alteromonadaceae 1236|Gammaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoK GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 ko:K00340 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q2 k141_33225_3 95619.PM1_0221720 5.92e-49 163.0 COG0839@1|root,COG0839@2|Bacteria,1MWJV@1224|Proteobacteria,1S65T@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Belongs to the complex I subunit 6 family nuoJ GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016021,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0031224,GO:0031226,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 ko:K00339 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - e_coli_core.b2280,iAF1260.b2280,iAPECO1_1312.APECO1_4285,iB21_1397.B21_02165,iBWG_1329.BWG_2054,iE2348C_1286.E2348C_2420,iEC042_1314.EC042_2521,iEC55989_1330.EC55989_2524,iECABU_c1320.ECABU_c26120,iECBD_1354.ECBD_1381,iECB_1328.ECB_02205,iECDH10B_1368.ECDH10B_2442,iECDH1ME8569_1439.ECDH1ME8569_2217,iECD_1391.ECD_02205,iECED1_1282.ECED1_2744,iECH74115_1262.ECH74115_3419,iECIAI1_1343.ECIAI1_2354,iECIAI39_1322.ECIAI39_2427,iECNA114_1301.ECNA114_2370,iECO103_1326.ECO103_2744,iECO111_1330.ECO111_3028,iECO26_1355.ECO26_3268,iECOK1_1307.ECOK1_2513,iECP_1309.ECP_2319,iECS88_1305.ECS88_2427,iECSE_1348.ECSE_2537,iECSF_1327.ECSF_2157,iECSP_1301.ECSP_3154,iECUMN_1333.ECUMN_2619,iECW_1372.ECW_m2468,iECs_1301.ECs3164,iEKO11_1354.EKO11_1487,iETEC_1333.ETEC_2415,iEcDH1_1363.EcDH1_1377,iEcE24377_1341.EcE24377A_2573,iEcHS_1320.EcHS_A2429,iEcSMS35_1347.EcSMS35_2434,iEcolC_1368.EcolC_1372,iJO1366.b2280,iJR904.b2280,iLF82_1304.LF82_1547,iNRG857_1313.NRG857_11545,iSBO_1134.SBO_2313,iSDY_1059.SDY_2476,iSFV_1184.SFV_2347,iSF_1195.SF2356,iSFxv_1172.SFxv_2600,iSSON_1240.SSON_2337,iS_1188.S2491,iSbBS512_1146.SbBS512_E2656,iUMN146_1321.UM146_05415,iUMNK88_1353.UMNK88_2830,iUTI89_1310.UTI89_C2560,iWFL_1372.ECW_m2468,iY75_1357.Y75_RS11955,iZ_1308.Z3539,ic_1306.c2821 Oxidored_q3 k141_33225_4 1279017.AQYJ01000023_gene3165 7.68e-103 299.0 COG1143@1|root,COG1143@2|Bacteria,1MV90@1224|Proteobacteria,1RN32@1236|Gammaproteobacteria,466PB@72275|Alteromonadaceae 1236|Gammaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoI - 1.6.5.3 ko:K00338 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Fer4,Fer4_7 k141_8126_1 252305.OB2597_04188 4.33e-53 178.0 COG1694@1|root,COG3956@2|Bacteria,1MVKM@1224|Proteobacteria,2TRC9@28211|Alphaproteobacteria,2PDK9@252301|Oceanicola 28211|Alphaproteobacteria S Phosphoribosyl-ATP pyrophosphohydrolase mazG GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009267,GO:0009394,GO:0009605,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042594,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.9 ko:K02499,ko:K04765 ko00230,ko00240,ko00760,ko00770,ko01100,map00230,map00240,map00760,map00770,map01100 - R00086,R00087,R00103,R00287,R00426,R00515,R00662,R00720,R03004,R03036,R11323 RC00002 ko00000,ko00001,ko01000,ko03036 - - - MazG k141_4692_1 1453501.JELR01000002_gene997 3.67e-118 344.0 COG3159@1|root,COG3159@2|Bacteria,1R4BP@1224|Proteobacteria,1S9SC@1236|Gammaproteobacteria,467JP@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria yigA - - ko:K09921 - - - - ko00000 - - - DUF484 k141_2295_2 272569.rrnAC1017 1.17e-24 107.0 COG0438@1|root,arCOG01403@2157|Archaea,2XVZZ@28890|Euryarchaeota,23SQ3@183963|Halobacteria 183963|Halobacteria M COG0438 Glycosyltransferase - - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1 k141_37924_1 218284.CCDN010000001_gene636 3.09e-79 240.0 COG3290@1|root,COG3290@2|Bacteria,1V8IS@1239|Firmicutes,4HQ4T@91061|Bacilli,1ZHUN@1386|Bacillus 91061|Bacilli T Sporulation initiation phospho-transferase B, C-terminal spo0B GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K06375 ko02020,ko02024,map02020,map02024 - - - ko00000,ko00001,ko01000 - - - SPOB_a,SPOB_ab k141_34478_1 1116375.VEJY3_11825 9.73e-64 204.0 COG2771@1|root,COG2771@2|Bacteria,1PDSX@1224|Proteobacteria,1TBHP@1236|Gammaproteobacteria,1XXYQ@135623|Vibrionales 135623|Vibrionales K COG2771 DNA-binding HTH domain-containing proteins - - - - - - - - - - - - GerE k141_2296_2 882082.SaccyDRAFT_1668 2.1e-19 87.8 COG0583@1|root,COG0583@2|Bacteria,2GMDV@201174|Actinobacteria,4E1HM@85010|Pseudonocardiales 201174|Actinobacteria K Bacterial regulatory helix-turn-helix protein, lysR family - - - - - - - - - - - - HTH_1,LysR_substrate k141_15297_2 864051.BurJ1DRAFT_1403 9.07e-11 70.1 COG0457@1|root,COG0457@2|Bacteria,1MUTV@1224|Proteobacteria,2VSDY@28216|Betaproteobacteria,1KNP3@119065|unclassified Burkholderiales 28216|Betaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16,TPR_19,TPR_8 k141_15297_3 1279017.AQYJ01000028_gene2133 2.16e-17 85.9 COG0834@1|root,COG4623@1|root,COG0834@2|Bacteria,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,1RM8W@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella - GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - ko:K18691 - - - - ko00000,ko01000,ko01011 - - - SBP_bac_3,SLT k141_36614_1 218284.CCDN010000005_gene3374 6.32e-63 204.0 COG1850@1|root,COG1850@2|Bacteria,1TSZQ@1239|Firmicutes,4HBIK@91061|Bacilli,1ZC2J@1386|Bacillus 91061|Bacilli G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P) mtnW GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0009853,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0016984,GO:0043094,GO:0044237 5.3.2.5 ko:K08965 ko00270,ko01100,map00270,map01100 M00034 R07393 RC02421 ko00000,ko00001,ko00002,ko01000 - - - RuBisCO_large,RuBisCO_large_N k141_28346_1 218284.CCDN010000002_gene2899 1.79e-90 267.0 COG1528@1|root,COG1528@2|Bacteria,1V1BJ@1239|Firmicutes,4HGPQ@91061|Bacilli,1ZR3A@1386|Bacillus 91061|Bacilli P Ferritin-like domain - - 1.16.3.2 ko:K02217 - - - - ko00000,ko01000 - - - Ferritin k141_28346_2 1307436.PBF_18404 2.31e-05 47.0 COG0697@1|root,COG0697@2|Bacteria,1TR8G@1239|Firmicutes,4HCXB@91061|Bacilli,1ZC8D@1386|Bacillus 91061|Bacilli EG EamA-like transporter family - - - - - - - - - - - - EamA k141_8128_1 223926.28805416 1.42e-164 470.0 COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,1XSK2@135623|Vibrionales 135623|Vibrionales M Belongs to the peptidase S1C family degQ - 3.4.21.107 ko:K04771,ko:K04772 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ,PDZ_2,Trypsin_2 k141_37926_1 218284.CCDN010000001_gene223 1.12e-52 169.0 COG1714@1|root,COG1714@2|Bacteria,1V6QH@1239|Firmicutes,4HJKR@91061|Bacilli,1ZRW8@1386|Bacillus 91061|Bacilli S membrane protein domain - - - - - - - - - - - - RDD k141_28378_1 1279017.AQYJ01000028_gene2093 4.31e-94 299.0 COG1913@1|root,COG1913@2|Bacteria,1MY52@1224|Proteobacteria,1RSIP@1236|Gammaproteobacteria,4646U@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF5117) - - - - - - - - - - - - DUF4953,DUF5117 k141_2334_1 861299.J421_3761 1.42e-27 113.0 COG4942@1|root,COG4942@2|Bacteria,1ZSU6@142182|Gemmatimonadetes 142182|Gemmatimonadetes D Peptidase family M23 - - - - - - - - - - - - Peptidase_M23 k141_4720_1 218284.CCDN010000002_gene2751 1.27e-130 379.0 COG0601@1|root,COG0601@2|Bacteria,1UYTT@1239|Firmicutes,4IEZM@91061|Bacilli,1ZJ9K@1386|Bacillus 91061|Bacilli EP Binding-protein-dependent transport system inner membrane component - - - - - - - - - - - - BPD_transp_1 k141_30627_1 1294265.JCM21738_5026 3.48e-135 385.0 arCOG13259@1|root,2ZCJ1@2|Bacteria,1V55Y@1239|Firmicutes,4IS41@91061|Bacilli,1ZS10@1386|Bacillus 91061|Bacilli E Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links tgl - 2.3.2.13 ko:K00686 - - - - ko00000,ko01000 - - - - k141_3513_1 935836.JAEL01000081_gene1183 3.71e-134 394.0 COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,4H9TI@91061|Bacilli,1ZBG7@1386|Bacillus 91061|Bacilli I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol ywiE GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0032048,GO:0032049,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 - ko:K06131 ko00564,ko01100,map00564,map01100 - R07390 RC00017 ko00000,ko00001,ko01000 - - iYO844.BSU37240 PLDc_2,PLDc_N k141_31752_1 1307436.PBF_10647 3.84e-101 307.0 COG1233@1|root,COG1233@2|Bacteria,1TRN1@1239|Firmicutes,4HA5W@91061|Bacilli,1ZDED@1386|Bacillus 91061|Bacilli Q Flavin containing amine oxidoreductase - - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 ko:K10027 ko00906,ko01100,ko01110,map00906,map01100,map01110 - R04787,R04798,R04800,R09691,R09692 RC01214,RC02088,RC02605 ko00000,ko00001,ko01000 - - - Amino_oxidase k141_28379_1 1294265.JCM21738_4472 6.91e-106 315.0 COG0826@1|root,COG0826@2|Bacteria,1TPRE@1239|Firmicutes,4HBEG@91061|Bacilli,1ZC7K@1386|Bacillus 91061|Bacilli O COG0826 Collagenase and related proteases yrrO - - ko:K08303 ko05120,map05120 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_U32,Peptidase_U32_C k141_28379_2 1294265.JCM21738_4471 1.29e-20 84.7 COG0826@1|root,COG0826@2|Bacteria,1TQIZ@1239|Firmicutes,4HA2T@91061|Bacilli,1ZAXB@1386|Bacillus 91061|Bacilli O Peptidase U32 yrrN - - ko:K08303 ko05120,map05120 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_U32 k141_36631_1 1042377.AFPJ01000012_gene1351 1.63e-09 57.0 COG0241@1|root,COG0241@2|Bacteria,1RDGR@1224|Proteobacteria,1S3UD@1236|Gammaproteobacteria,467KG@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0241 Histidinol phosphatase and related phosphatases gmhB - 3.1.3.82,3.1.3.83 ko:K03273 ko00540,ko01100,map00540,map01100 M00064 R05647,R09771 RC00017 ko00000,ko00001,ko00002,ko01000,ko01005 - - iJN746.PP_0059 Hydrolase_like k141_36631_2 1042377.AFPJ01000012_gene1350 3.33e-72 228.0 COG1092@1|root,COG1092@2|Bacteria,1MUGB@1224|Proteobacteria,1RN7Z@1236|Gammaproteobacteria,464TP@72275|Alteromonadaceae 1236|Gammaproteobacteria J Specifically methylates the cytosine at position 1962 (m5C1962) of 23S rRNA rlmI - 2.1.1.191 ko:K06969 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_SAM k141_4722_1 1385513.N780_08240 2.21e-74 244.0 COG0737@1|root,COG0737@2|Bacteria,1TPV2@1239|Firmicutes,4H9VJ@91061|Bacilli 91061|Bacilli F Belongs to the 5'-nucleotidase family - - 3.1.3.5,3.6.1.45 ko:K01081,ko:K07004,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - 5_nucleotid_C,CHB_HEX_C_1,CW_binding_2,LTD,Metallophos,SLH k141_2336_1 1453501.JELR01000002_gene811 4.84e-62 208.0 COG1409@1|root,COG1409@2|Bacteria,1R3RY@1224|Proteobacteria,1RPT2@1236|Gammaproteobacteria,4664I@72275|Alteromonadaceae 1236|Gammaproteobacteria S Calcineurin-like phosphoesterase - - - - - - - - - - - - Metallophos k141_3514_1 1453501.JELR01000001_gene2840 1.86e-177 501.0 COG0585@1|root,COG0585@2|Bacteria,1MXHD@1224|Proteobacteria,1RPRF@1236|Gammaproteobacteria,465C2@72275|Alteromonadaceae 1236|Gammaproteobacteria J Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs truD GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 ko:K06176 - - - - ko00000,ko01000,ko03016 - - - TruD k141_36633_1 1280390.CBQR020000029_gene660 2.96e-26 109.0 COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,4HAW3@91061|Bacilli,26S3W@186822|Paenibacillaceae 91061|Bacilli K Catabolite control protein A - - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_1,Peripla_BP_3 k141_33258_1 768066.HELO_3910 4.8e-84 267.0 COG1181@1|root,COG1181@2|Bacteria,1R4RC@1224|Proteobacteria,1T297@1236|Gammaproteobacteria 1236|Gammaproteobacteria M ATP-grasp domain - - - - - - - - - - - - ATP-grasp_4,CPSase_L_D2 k141_33258_2 323850.Shew_3346 6.77e-15 76.6 COG4461@1|root,COG4461@2|Bacteria,1R6Q3@1224|Proteobacteria,1S2QD@1236|Gammaproteobacteria,2Q9NS@267890|Shewanellaceae 1236|Gammaproteobacteria S Lysozyme inhibitor LprI - - - - - - - - - - - - LprI,MliC k141_3515_1 926550.CLDAP_01250 1.06e-78 244.0 COG1209@1|root,COG1209@2|Bacteria,2G6MR@200795|Chloroflexi 200795|Chloroflexi M PFAM Nucleotidyl transferase - - 2.7.7.24 ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 M00793 R02328 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase k141_36634_1 218284.CCDN010000002_gene2204 2.82e-120 353.0 28HWT@1|root,2Z82P@2|Bacteria,1TSBJ@1239|Firmicutes,4HCMR@91061|Bacilli,1ZB7P@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - Xpo1 k141_8166_1 1042377.AFPJ01000012_gene1358 1.46e-133 389.0 COG0144@1|root,COG0144@2|Bacteria,1MWPE@1224|Proteobacteria,1RN8X@1236|Gammaproteobacteria,465KP@72275|Alteromonadaceae 1236|Gammaproteobacteria J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA sun GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 ko:K03500 - - - - ko00000,ko01000,ko03009 - - - Methyltr_RsmB-F,Methyltr_RsmF_N,NusB k141_2339_1 218284.CCDN010000001_gene1668 1.71e-101 315.0 COG3973@1|root,COG3973@2|Bacteria,1TP39@1239|Firmicutes,4H9Y5@91061|Bacilli,1ZAWP@1386|Bacillus 91061|Bacilli L DNA helicase uvrD - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_19,UvrD-helicase,UvrD_C,UvrD_C_2 k141_15303_1 1042377.AFPJ01000011_gene428 3.84e-39 139.0 COG0760@1|root,COG0760@2|Bacteria,1R4ZR@1224|Proteobacteria,1SEDW@1236|Gammaproteobacteria,46943@72275|Alteromonadaceae 1236|Gammaproteobacteria O PPIC-type PPIASE domain - - - - - - - - - - - - Rotamase_2 k141_15303_2 1042377.AFPJ01000020_gene2063 0.0 981.0 28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,1RRUM@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF3604) - - - - - - - - - - - - DUF3604 k141_15303_5 1279017.AQYJ01000022_gene2657 3.05e-153 442.0 COG2207@1|root,COG2207@2|Bacteria,1P4M5@1224|Proteobacteria,1SB0I@1236|Gammaproteobacteria,46B4Z@72275|Alteromonadaceae 1236|Gammaproteobacteria K helix_turn_helix, arabinose operon control protein - - - - - - - - - - - - HTH_18 k141_15303_6 1279017.AQYJ01000022_gene2658 3.85e-105 306.0 COG0741@1|root,COG0741@2|Bacteria,1R666@1224|Proteobacteria,1S3XT@1236|Gammaproteobacteria,4675S@72275|Alteromonadaceae 1236|Gammaproteobacteria M Transglycosylase SLT domain - - - - - - - - - - - - SLT k141_15303_7 1279017.AQYJ01000022_gene2659 0.0 1030.0 COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,1RN5R@1236|Gammaproteobacteria,4652J@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS proS GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0043906,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iUTI89_1310.UTI89_C0210 HGTP_anticodon,tRNA-synt_2b,tRNA_edit k141_15303_11 1453501.JELR01000001_gene3186 8.52e-162 454.0 COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,1RP5N@1236|Gammaproteobacteria,465EW@72275|Alteromonadaceae 1236|Gammaproteobacteria K transcriptional regulatory protein yebC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0044424,GO:0044444,GO:0044464,GO:0050896 - - - - - - - - - - Transcrip_reg k141_15303_12 1279017.AQYJ01000028_gene2500 5.26e-114 330.0 COG0204@1|root,COG0204@2|Bacteria,1RJMS@1224|Proteobacteria,1S71V@1236|Gammaproteobacteria,467SS@72275|Alteromonadaceae 1236|Gammaproteobacteria I Phosphate acyltransferases - - - - - - - - - - - - Acyltransferase k141_15303_13 1279017.AQYJ01000028_gene2501 2.84e-247 692.0 COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,1RNPZ@1236|Gammaproteobacteria,4643D@72275|Alteromonadaceae 1236|Gammaproteobacteria L May be involved in recombinational repair of damaged DNA recN GO:0000724,GO:0000725,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 - ko:K03631 - - - - ko00000,ko03400 - - - AAA_23,SMC_N k141_31755_1 218284.CCDN010000008_gene4147 8.49e-117 343.0 COG4948@1|root,COG4948@2|Bacteria,1TQMS@1239|Firmicutes,4HBMX@91061|Bacilli,1ZBMS@1386|Bacillus 91061|Bacilli H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) menC GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.2.1.113 ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R04031 RC01053 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU30780 MR_MLE_C,MR_MLE_N k141_21334_1 945543.VIBR0546_10659 1.24e-75 239.0 COG0352@1|root,COG0352@2|Bacteria,1QTW3@1224|Proteobacteria,1T1YB@1236|Gammaproteobacteria,1XSWF@135623|Vibrionales 135623|Vibrionales H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) thiE - 2.5.1.3 ko:K00788 ko00730,ko01100,map00730,map01100 M00127 R03223,R10712 RC00224,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 - - - TMP-TENI k141_21334_2 223926.28808051 2.91e-147 419.0 COG0476@1|root,COG0476@2|Bacteria,1MW7H@1224|Proteobacteria,1RPJ3@1236|Gammaproteobacteria,1XV7V@135623|Vibrionales 135623|Vibrionales H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 thiF - 2.7.7.73 ko:K03148 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07459 RC00043 ko00000,ko00001,ko01000 - - - ThiF k141_21334_3 1116375.VEJY3_15235 5.45e-31 111.0 COG2104@1|root,COG2104@2|Bacteria,1NG8E@1224|Proteobacteria,1SGCU@1236|Gammaproteobacteria,1XYZ1@135623|Vibrionales 135623|Vibrionales H COG2104 Sulfur transfer protein involved in thiamine biosynthesis thiS - - ko:K03154 ko04122,map04122 - - - ko00000,ko00001 - - - ThiS k141_21334_4 223926.28808049 3.29e-159 449.0 COG2022@1|root,COG2022@2|Bacteria,1N0N5@1224|Proteobacteria,1RMPD@1236|Gammaproteobacteria,1XT63@135623|Vibrionales 135623|Vibrionales H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S thiG GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 ko:K03149 ko00730,ko01100,map00730,map01100 - R10247 RC03096,RC03097,RC03461 ko00000,ko00001,ko01000 - - - ThiG k141_21334_5 1116375.VEJY3_15225 1.88e-252 694.0 COG0502@1|root,COG0502@2|Bacteria,1MXK0@1224|Proteobacteria,1RNTV@1236|Gammaproteobacteria,1XV3B@135623|Vibrionales 135623|Vibrionales C COG1060 Thiamine biosynthesis enzyme ThiH and related thiH - 4.1.99.19 ko:K03150 ko00730,ko01100,map00730,map01100 - R10246 RC01434,RC03095 ko00000,ko00001,ko01000 - - - BATS,Radical_SAM k141_21334_6 1116375.VEJY3_15220 5.97e-157 454.0 COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,1RPQD@1236|Gammaproteobacteria,1XST4@135623|Vibrionales 135623|Vibrionales E COG0006 Xaa-Pro aminopeptidase ampP - 3.4.11.9 ko:K01262 - - - - ko00000,ko01000,ko01002 - - - Creatinase_N,Creatinase_N_2,Peptidase_M24,Peptidase_M24_C k141_2340_1 317936.Nos7107_3195 1.32e-30 124.0 COG2706@1|root,COG2706@2|Bacteria 2|Bacteria G 6-phosphogluconolactonase activity - - - - - - - - - - - - Lactonase k141_21335_1 1158610.UC3_01459 3.08e-16 79.0 COG2377@1|root,COG2377@2|Bacteria,1TSBU@1239|Firmicutes,4HAYA@91061|Bacilli,4B0H4@81852|Enterococcaceae 91061|Bacilli F Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling anmK - 2.7.1.170 ko:K09001 - - - - ko00000,ko01000 - - - AnmK k141_21335_2 234621.RER_12180 4.92e-12 66.6 COG2103@1|root,COG2103@2|Bacteria,2GN0K@201174|Actinobacteria,4G08N@85025|Nocardiaceae 201174|Actinobacteria S Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate murQ - 4.2.1.126 ko:K07106 ko00520,ko01100,map00520,map01100 - R08555 RC00397,RC00746 ko00000,ko00001,ko01000 - - - BcrAD_BadFG,SIS,SIS_2 k141_15304_1 1150600.ADIARSV_0488 1.15e-28 117.0 28JIP@1|root,2Z82C@2|Bacteria,4NFN9@976|Bacteroidetes,1IS0A@117747|Sphingobacteriia 976|Bacteroidetes S S1/P1 Nuclease - - - - - - - - - - - - S1-P1_nuclease k141_28380_1 713586.KB900536_gene1962 1.35e-152 450.0 COG2936@1|root,COG2936@2|Bacteria,1MVA8@1224|Proteobacteria,1RN7H@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Peptidase S15 cocE - - ko:K06978 - - - - ko00000 - - - PepX_C,Peptidase_S15 k141_28380_2 161528.ED21_20974 1.05e-20 93.2 COG0526@1|root,COG0526@2|Bacteria,1N81A@1224|Proteobacteria,2UGCI@28211|Alphaproteobacteria,2K7HK@204457|Sphingomonadales 204457|Sphingomonadales CO Thioredoxin-like - - - - - - - - - - - - Thioredoxin_7 k141_4725_2 1279017.AQYJ01000018_gene773 1.46e-58 183.0 COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,1S3QE@1236|Gammaproteobacteria,4683Z@72275|Alteromonadaceae 1236|Gammaproteobacteria FG Scavenger mRNA decapping enzyme C-term binding - - - ko:K02503 - - - - ko00000,ko04147 - - - HIT k141_4725_3 247634.GPB2148_3063 3.7e-30 107.0 COG2835@1|root,COG2835@2|Bacteria,1N6Y2@1224|Proteobacteria,1SCFF@1236|Gammaproteobacteria,1J6W1@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Belongs to the UPF0434 family ycaR GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K09791 - - - - ko00000 - - - Trm112p k141_33260_1 218284.CCDN010000002_gene2245 4.14e-184 520.0 COG0441@1|root,COG0441@2|Bacteria,1UHT4@1239|Firmicutes,4IS8T@91061|Bacilli,1ZS31@1386|Bacillus 91061|Bacilli J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) proS - 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,ProRS-C_1,tRNA-synt_2b k141_8168_1 1121423.JONT01000004_gene1733 3.49e-63 221.0 COG1615@1|root,COG1615@2|Bacteria,1TQHM@1239|Firmicutes,248PM@186801|Clostridia,260EY@186807|Peptococcaceae 186801|Clostridia S PFAM Uncharacterised protein family UPF0182 - - - ko:K09118 - - - - ko00000 - - - UPF0182 k141_21336_1 1123368.AUIS01000014_gene2288 7.11e-57 180.0 COG0394@1|root,COG0394@2|Bacteria,1MWYQ@1224|Proteobacteria,1S2YD@1236|Gammaproteobacteria,2NCUY@225057|Acidithiobacillales 225057|Acidithiobacillales T low molecular weight - - 1.20.4.1 ko:K03741 - - - - ko00000,ko01000 - - - LMWPc k141_30631_1 218284.CCDN010000002_gene1983 1.03e-155 445.0 COG0026@1|root,COG0026@2|Bacteria,1TQCD@1239|Firmicutes,4H9M5@91061|Bacilli,1ZB8P@1386|Bacillus 91061|Bacilli F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) purK GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 6.3.4.18 ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07404 RC01927 ko00000,ko00001,ko00002,ko01000 - - - 2-Hacid_dh_C,ATP-grasp k141_30631_2 218284.CCDN010000002_gene1984 1.15e-65 211.0 COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,4HACW@91061|Bacilli,1ZC7P@1386|Bacillus 91061|Bacilli F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily purB GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS09895 ADSL_C,Lyase_1 k141_17827_1 1116375.VEJY3_24106 7.46e-144 411.0 COG4594@1|root,COG4594@2|Bacteria,1R01Z@1224|Proteobacteria,1T4DX@1236|Gammaproteobacteria,1Y26N@135623|Vibrionales 135623|Vibrionales P transporter Substrate-binding - - - ko:K02016 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - Peripla_BP_2 k141_32219_1 351746.Pput_3432 1.31e-112 337.0 COG2079@1|root,COG2079@2|Bacteria,1MUIG@1224|Proteobacteria,1RPQN@1236|Gammaproteobacteria,1YY5Q@136845|Pseudomonas putida group 1236|Gammaproteobacteria S 2-methylcitrate dehydratase prpD GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019679,GO:0019752,GO:0032787,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0046459,GO:0047547,GO:0048037,GO:0051536,GO:0051537,GO:0051540,GO:0071704,GO:0072329,GO:1901575 4.2.1.79 ko:K01720 ko00640,map00640 - R04424 RC01152 ko00000,ko00001,ko01000 - - iEcolC_1368.EcolC_3291 MmgE_PrpD k141_31121_1 218284.CCDN010000005_gene3293 3.77e-82 244.0 COG2346@1|root,COG2346@2|Bacteria,1V6JN@1239|Firmicutes,4HHQG@91061|Bacilli,1ZG81@1386|Bacillus 91061|Bacilli S COG2346 Truncated hemoglobins yjbI - - ko:K06886 - - - - ko00000 - - - Bac_globin k141_6206_1 370438.PTH_1956 2.27e-144 432.0 COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,248CH@186801|Clostridia,25ZYB@186807|Peptococcaceae 186801|Clostridia J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) thrS - 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD k141_256_1 1033734.CAET01000077_gene2847 3.12e-08 54.7 COG1333@1|root,COG1333@2|Bacteria,1TQ6C@1239|Firmicutes,4HAFD@91061|Bacilli,1ZBB3@1386|Bacillus 91061|Bacilli O COG1333 ResB protein required for cytochrome c biosynthesis resB - - ko:K07399 - - - - ko00000 - - - ResB k141_256_2 218284.CCDN010000001_gene1062 5.42e-107 318.0 COG0755@1|root,COG0755@2|Bacteria,1TQZ4@1239|Firmicutes,4HA2N@91061|Bacilli,1ZBH9@1386|Bacillus 91061|Bacilli O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component' resC GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008152,GO:0015886,GO:0016020,GO:0044464,GO:0051179,GO:0051181,GO:0051234,GO:0055114,GO:0071702,GO:0071705,GO:0071944,GO:1901678 - - - - - - - - - - Cytochrom_C_asm k141_7321_1 1294265.JCM21738_1233 5.26e-132 383.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,1ZB7V@1386|Bacillus 91061|Bacilli I Belongs to the thiolase family pcaF - 2.3.1.174,2.3.1.223 ko:K02615 ko00360,ko01120,map00360,map01120 - R00829,R09839 RC00004,RC00326,RC03003 ko00000,ko00001,ko01000 - - - Thiolase_C,Thiolase_N k141_35802_1 218284.CCDN010000007_gene3893 6e-104 307.0 COG0225@1|root,COG0229@1|root,COG0225@2|Bacteria,COG0229@2|Bacteria,1TQ3E@1239|Firmicutes,4HAIV@91061|Bacilli,1ZCC5@1386|Bacillus 91061|Bacilli O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine msrB - 1.8.4.11,1.8.4.12 ko:K12267 - - - - ko00000,ko01000 - - - PMSR,SelR k141_8530_2 218284.CCDN010000001_gene1215 6.87e-128 367.0 COG1788@1|root,COG1788@2|Bacteria,1TSZT@1239|Firmicutes,4HDJG@91061|Bacilli,1ZQEH@1386|Bacillus 91061|Bacilli I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit atoD - 2.8.3.8,2.8.3.9 ko:K01034 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 - R01179,R01359,R01365,R07832 RC00012,RC00014 ko00000,ko00001,ko01000 - - - CoA_trans k141_8530_3 218284.CCDN010000001_gene1214 4.09e-169 484.0 COG0161@1|root,COG0161@2|Bacteria,1TP9N@1239|Firmicutes,4HD8E@91061|Bacilli,1ZAWS@1386|Bacillus 91061|Bacilli H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family yodT - - - - - - - - - - - Aminotran_3 k141_16808_1 1453501.JELR01000002_gene325 0.0 1134.0 COG1629@1|root,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria,4651V@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_23926_1 218284.CCDN010000001_gene1882 3.32e-91 286.0 COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,4H9Z3@91061|Bacilli,1ZB24@1386|Bacillus 91061|Bacilli J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction pnp GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 M00394 R00437,R00438,R00439,R00440 RC02795 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 - - - KH_1,PNPase,RNase_PH,RNase_PH_C,S1 k141_32220_2 1196028.ALEF01000005_gene3304 7.96e-26 102.0 COG0697@1|root,COG0697@2|Bacteria,1V038@1239|Firmicutes,4HDBV@91061|Bacilli 91061|Bacilli EG EamA-like transporter family - - - - - - - - - - - - EamA k141_27496_2 1279017.AQYJ01000028_gene2048 5.18e-13 65.1 COG1188@1|root,COG1188@2|Bacteria,1MZR6@1224|Proteobacteria,1S8VU@1236|Gammaproteobacteria,467YZ@72275|Alteromonadaceae 1236|Gammaproteobacteria J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) hslR GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003727,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009451,GO:0009628,GO:0009987,GO:0016070,GO:0033554,GO:0034605,GO:0034641,GO:0043021,GO:0043023,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - ko:K04762 - - - - ko00000,ko03110 - - - S4 k141_28770_1 218284.CCDN010000007_gene3806 4.5e-117 343.0 COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,4H9SQ@91061|Bacilli,1ZBUI@1386|Bacillus 91061|Bacilli J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner ychF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - ko:K06942 - - - - ko00000,ko03009 - - - MMR_HSR1,YchF-GTPase_C k141_7322_1 218284.CCDN010000011_gene4416 5.94e-94 285.0 COG0013@1|root,COG0013@2|Bacteria,1TSBZ@1239|Firmicutes,4HADV@91061|Bacilli,1ZDMJ@1386|Bacillus 91061|Bacilli J metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain alaS_2 - 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DHHA1,tRNA-synt_2c,tRNA_SAD k141_25116_1 1453501.JELR01000002_gene867 6.14e-112 335.0 COG2936@1|root,COG2936@2|Bacteria,1QU2I@1224|Proteobacteria,1S1VW@1236|Gammaproteobacteria,469YI@72275|Alteromonadaceae 1236|Gammaproteobacteria S X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain - - - - - - - - - - - - PepX_C,Peptidase_S15 k141_15675_1 1347369.CCAD010000039_gene621 5.01e-48 154.0 COG4703@1|root,COG4703@2|Bacteria,1VKD0@1239|Firmicutes,4HRGC@91061|Bacilli,1ZI15@1386|Bacillus 91061|Bacilli S protein conserved in bacteria ykuJ - - - - - - - - - - - DUF1797 k141_7348_1 283942.IL0684 3.42e-55 200.0 COG4643@1|root,COG4643@2|Bacteria,1N08G@1224|Proteobacteria,1RTFA@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Protein of unknown function (DUF3987) - - - - - - - - - - - - DUF3987 k141_7348_2 1390370.O203_10800 4.57e-13 78.2 COG0582@1|root,COG0582@2|Bacteria,1RAN4@1224|Proteobacteria 1224|Proteobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_integrase k141_4927_2 1042377.AFPJ01000012_gene1390 3.31e-192 536.0 COG0109@1|root,COG0109@2|Bacteria,1MW3S@1224|Proteobacteria,1RNHC@1236|Gammaproteobacteria,465UQ@72275|Alteromonadaceae 1236|Gammaproteobacteria O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group cyoE GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 M00154 R07411 RC01786 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 - - iJN746.PP_0110 UbiA k141_3803_1 1453501.JELR01000002_gene1312 2.51e-76 234.0 COG1218@1|root,COG1218@2|Bacteria,1N0GY@1224|Proteobacteria,1RP5A@1236|Gammaproteobacteria,4642N@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1218 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase cysQ - 3.1.3.7 ko:K01082 ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130 - R00188,R00508 RC00078 ko00000,ko00001,ko01000,ko03016 - - - Inositol_P k141_33459_1 649639.Bcell_0780 4.52e-37 133.0 COG1834@1|root,COG1834@2|Bacteria,1VDT8@1239|Firmicutes,4ISAW@91061|Bacilli,1ZCTN@1386|Bacillus 91061|Bacilli E Amidinotransferase ykgA - - - - - - - - - - - Amidinotransf k141_23956_1 406124.ACPC01000018_gene2700 2.01e-133 387.0 COG0280@1|root,COG0280@2|Bacteria,1TRQU@1239|Firmicutes,4HBSK@91061|Bacilli,1ZC49@1386|Bacillus 91061|Bacilli C phosphate butyryltransferase ptb - 2.3.1.19 ko:K00634 ko00650,ko01100,map00650,map01100 - R01174 RC00004,RC02816 ko00000,ko00001,ko01000 - - iYO844.BSU24090 PTA_PTB k141_7349_1 1042377.AFPJ01000037_gene2846 3.51e-16 75.1 COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,1RMT6@1236|Gammaproteobacteria,46577@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism adk GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004017,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006412,GO:0006518,GO:0006629,GO:0006644,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0010467,GO:0015949,GO:0015950,GO:0015951,GO:0016070,GO:0016208,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019205,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 - - iECH74115_1262.ECH74115_0566,iEKO11_1354.EKO11_3373,iG2583_1286.G2583_0586,iJN746.PP_1506 ADK,ADK_lid k141_22776_1 1283337.B0ZSI6_BPHA1 4e-82 249.0 4QAQ1@10239|Viruses,4QZG4@35237|dsDNA viruses no RNA stage,4QR8N@28883|Caudovirales,4QJAH@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k141_1352_1 1219076.N646_0921 1.21e-35 122.0 COG3668@1|root,COG3668@2|Bacteria,1MZUQ@1224|Proteobacteria,1SANN@1236|Gammaproteobacteria,1XXZC@135623|Vibrionales 135623|Vibrionales S ParE toxin of type II toxin-antitoxin system, parDE - - - - - - - - - - - - ParE_toxin k141_1352_2 1280001.BAOA01000234_gene3504 1.45e-45 148.0 2DZUD@1|root,32VJ8@2|Bacteria,1N044@1224|Proteobacteria,1S8TH@1236|Gammaproteobacteria,1XXVQ@135623|Vibrionales 135623|Vibrionales S RelB antitoxin - - - - - - - - - - - - RelB k141_1352_5 617140.AJZE01000060_gene4562 1.94e-33 119.0 2EJ23@1|root,33CT8@2|Bacteria,1NHHZ@1224|Proteobacteria,1SJII@1236|Gammaproteobacteria,1XYFP@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_18096_1 1279017.AQYJ01000022_gene2584 1.37e-61 209.0 COG0672@1|root,COG2010@1|root,COG0672@2|Bacteria,COG2010@2|Bacteria,1MXHM@1224|Proteobacteria,1RMWB@1236|Gammaproteobacteria,4661C@72275|Alteromonadaceae 1236|Gammaproteobacteria C Iron permease FTR1 family efeU_1 - - ko:K07243 - - - - ko00000,ko02000 2.A.108.1,2.A.108.2 - - Cytochrome_CBB3,FTR1 k141_28776_1 218284.CCDN010000002_gene2487 1.53e-125 363.0 COG4569@1|root,COG4569@2|Bacteria,1TQJS@1239|Firmicutes,4HCRZ@91061|Bacilli,1ZEE6@1386|Bacillus 91061|Bacilli Q Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds mhpF - 1.2.1.10 ko:K04073 ko00360,ko00362,ko00620,ko00621,ko00622,ko00650,ko01100,ko01120,ko01220,map00360,map00362,map00620,map00621,map00622,map00650,map01100,map01120,map01220 M00545,M00569 R00228,R01172 RC00004,RC00184,RC01195 br01602,ko00000,ko00001,ko00002,ko01000 - - - AcetDehyd-dimer,Semialdhyde_dh k141_10858_2 1279017.AQYJ01000027_gene1986 3.2e-151 428.0 COG0106@1|root,COG0106@2|Bacteria,1MW6S@1224|Proteobacteria,1RN3M@1236|Gammaproteobacteria,464AA@72275|Alteromonadaceae 1236|Gammaproteobacteria E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase hisA - 5.3.1.16,5.3.1.24 ko:K01814,ko:K01817 ko00340,ko00400,ko01100,ko01110,ko01130,ko01230,map00340,map00400,map01100,map01110,map01130,map01230 M00023,M00026 R03509,R04640 RC00945 ko00000,ko00001,ko00002,ko01000 - - - His_biosynth k141_33461_1 265729.GS18_0219570 1.1e-64 211.0 COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TPJ8@1239|Firmicutes,4HA8X@91061|Bacilli,1ZC2B@1386|Bacillus 91061|Bacilli G IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar ptsG - 2.7.1.208 ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 M00265,M00266,M00268,M00270,M00272,M00303,M00806 R02738,R02780,R04111,R04394,R05132,R08559 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.1,4.A.1.1.11,4.A.1.1.12 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC k141_2607_1 1384056.N787_04805 4.15e-62 223.0 COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,1RNVA@1236|Gammaproteobacteria,1X6C3@135614|Xanthomonadales 135614|Xanthomonadales S Putative 2OG-Fe(II) oxygenase - - - - - - - - - - - - 2OG-FeII_Oxy_5,TPR_16,TPR_19 k141_2607_2 291985.CCSI01000006_gene1132 1.83e-36 132.0 COG3751@1|root,COG3751@2|Bacteria,1N3MA@1224|Proteobacteria,2VGIM@28211|Alphaproteobacteria 28211|Alphaproteobacteria O 2OG-Fe(II) oxygenase superfamily - - - - - - - - - - - - 2OG-FeII_Oxy_4 k141_12111_1 1294265.JCM21738_4606 7.24e-203 569.0 COG1066@1|root,COG1066@2|Bacteria,1TQ7Y@1239|Firmicutes,4H9YC@91061|Bacilli,1ZB8H@1386|Bacillus 91061|Bacilli O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function radA - - ko:K04485 - - - - ko00000,ko03400 - - - AAA_25,ATPase,ChlI k141_23958_2 218284.CCDN010000001_gene653 2.79e-97 292.0 COG0343@1|root,COG0343@2|Bacteria,1TNZ4@1239|Firmicutes,4HCNM@91061|Bacilli,1ZBFJ@1386|Bacillus 91061|Bacilli F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) tgt GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 ko:K00773 - - R03789,R10209 RC00063 ko00000,ko01000,ko03016 - - - TGT k141_31153_2 1040989.AWZU01000049_gene936 2.24e-10 63.2 COG0454@1|root,COG0456@2|Bacteria,1RHHF@1224|Proteobacteria,2U9RG@28211|Alphaproteobacteria,3JZY3@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1 k141_12112_1 1294265.JCM21738_2312 1.54e-99 294.0 COG1526@1|root,COG1526@2|Bacteria,1TU8R@1239|Firmicutes,4HAY8@91061|Bacilli,1ZBNJ@1386|Bacillus 91061|Bacilli C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH fdhD - - ko:K02379 - - - - ko00000 - - - FdhD-NarQ k141_16826_1 997296.PB1_06582 2.46e-82 244.0 COG0096@1|root,COG0096@2|Bacteria,1V3KK@1239|Firmicutes,4HH32@91061|Bacilli,1ZFMC@1386|Bacillus 91061|Bacilli J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit rpsH GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02994 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S8 k141_16826_2 218284.CCDN010000010_gene4351 6.82e-114 328.0 COG0097@1|root,COG0097@2|Bacteria,1V1FC@1239|Firmicutes,4HFQD@91061|Bacilli,1ZCR5@1386|Bacillus 91061|Bacilli J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center rplF GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02933 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L6 k141_16826_3 218284.CCDN010000010_gene4350 6.56e-70 212.0 COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,4HIGF@91061|Bacilli,1ZG7C@1386|Bacillus 91061|Bacilli J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance rplR GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - ko:K02881 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L18p k141_33462_1 1385511.N783_11530 1.61e-32 129.0 COG1256@1|root,COG4786@1|root,COG1256@2|Bacteria,COG4786@2|Bacteria,1TPXH@1239|Firmicutes,4HAKM@91061|Bacilli,2Y9Q6@289201|Pontibacillus 91061|Bacilli N Flagellar hook-associated protein 1 flgK - - ko:K02396 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C k141_2608_1 218284.CCDN010000007_gene3785 2.02e-91 277.0 COG2206@1|root,COG2206@2|Bacteria,1TR95@1239|Firmicutes,4HB8S@91061|Bacilli,1ZCD6@1386|Bacillus 91061|Bacilli T HD domain M1-161 - - - - - - - - - - - HD,HD_5 k141_7351_1 1200792.AKYF01000019_gene4647 7.72e-16 75.1 COG1443@1|root,COG1443@2|Bacteria,1V6SB@1239|Firmicutes,4HJ2T@91061|Bacilli,26XCW@186822|Paenibacillaceae 91061|Bacilli I Nudix hydrolase M1-740 - - - - - - - - - - - NUDIX k141_7351_2 1117379.BABA_12176 2.26e-17 75.9 COG2378@1|root,COG2378@2|Bacteria,1VKU6@1239|Firmicutes,4HREU@91061|Bacilli,1ZJYY@1386|Bacillus 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - WYL k141_7351_3 1294265.JCM21738_1885 7.08e-11 61.6 COG4666@1|root,COG4666@2|Bacteria,1TP0V@1239|Firmicutes,4HC4B@91061|Bacilli,1ZAWZ@1386|Bacillus 91061|Bacilli S Tripartite ATP-independent periplasmic transporter, DctM component siaT_4 - - - - - - - - - - - DUF3394,DctM k141_22777_1 218284.CCDN010000002_gene2879 5.66e-84 265.0 COG1001@1|root,COG1001@2|Bacteria,1TP84@1239|Firmicutes,4HBB2@91061|Bacilli,1ZCHI@1386|Bacillus 91061|Bacilli F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family ade GO:0003674,GO:0003824,GO:0006040,GO:0006044,GO:0006046,GO:0008150,GO:0008152,GO:0008448,GO:0009056,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0046348,GO:0071704,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901575 3.5.4.2 ko:K01486 ko00230,ko01100,map00230,map01100 - R01244 RC00477 ko00000,ko00001,ko01000 - - iYO844.BSU14520 Adenine_deam_C,Amidohydro_1 k141_3805_2 1453501.JELR01000002_gene757 5.63e-202 561.0 COG0583@1|root,COG0583@2|Bacteria,1QYAP@1224|Proteobacteria,1RYE8@1236|Gammaproteobacteria,46591@72275|Alteromonadaceae 1236|Gammaproteobacteria K Bacterial regulatory helix-turn-helix protein, lysR family - - - ko:K21699 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate k141_10860_1 272134.KB731324_gene3199 1.52e-28 110.0 COG0705@1|root,COG0705@2|Bacteria,1FZY1@1117|Cyanobacteria,1H9IP@1150|Oscillatoriales 1117|Cyanobacteria S (Rhomboid) family - - - - - - - - - - - - Rhomboid k141_21641_1 1149133.ppKF707_1912 4.22e-58 201.0 COG0188@1|root,COG0188@2|Bacteria,1MURI@1224|Proteobacteria,1RMTC@1236|Gammaproteobacteria,1YEVJ@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parC GO:0000819,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006276,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007059,GO:0007062,GO:0008150,GO:0008152,GO:0009330,GO:0009987,GO:0016020,GO:0016043,GO:0019897,GO:0019898,GO:0022402,GO:0030541,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0098813,GO:1901360,GO:1901363 - ko:K02621 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseA_C,DNA_topoisoIV k141_25158_1 218284.CCDN010000001_gene1727 1.37e-46 152.0 COG3216@1|root,COG3216@2|Bacteria,1VG1Z@1239|Firmicutes,4HQ47@91061|Bacilli,1ZHV3@1386|Bacillus 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2062) - - - ko:K09928 - - - - ko00000 - - - DUF2062 k141_28777_1 1453501.JELR01000001_gene2018 1.74e-79 261.0 COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,1RN05@1236|Gammaproteobacteria,464MR@72275|Alteromonadaceae 1236|Gammaproteobacteria S Insulinase (Peptidase family M16) ptrA - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C k141_33463_1 1042377.AFPJ01000007_gene1946 1.25e-80 245.0 COG1209@1|root,COG1209@2|Bacteria,1MU0X@1224|Proteobacteria,1RMTR@1236|Gammaproteobacteria,4640A@72275|Alteromonadaceae 1236|Gammaproteobacteria M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis rfbA GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0008879,GO:0009058,GO:0009059,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0033692,GO:0034637,GO:0034645,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0045226,GO:0046379,GO:0046872,GO:0071704,GO:1901576 2.7.7.24 ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 M00793 R02328 RC00002 ko00000,ko00001,ko00002,ko01000 - - iSDY_1059.SDY_2206,iSF_1195.SF2102,iSFxv_1172.SFxv_2338,iS_1188.S2225 NTP_transferase k141_33463_2 1095743.HMPREF1054_0458 4e-68 210.0 COG1898@1|root,COG1898@2|Bacteria,1R9YD@1224|Proteobacteria,1S245@1236|Gammaproteobacteria,1Y7KU@135625|Pasteurellales 135625|Pasteurellales G Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose - - 5.1.3.13 ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R06514 RC01531 ko00000,ko00001,ko00002,ko01000 - - - dTDP_sugar_isom k141_37006_2 574376.BAMA_06660 3.59e-97 293.0 COG4221@1|root,COG4221@2|Bacteria,1TQDY@1239|Firmicutes,4HBS5@91061|Bacilli,1ZB88@1386|Bacillus 91061|Bacilli S Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short k141_288_2 1279017.AQYJ01000026_gene371 7.96e-100 301.0 COG5495@1|root,COG5495@2|Bacteria,1RBEZ@1224|Proteobacteria,1S847@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF2520) - - - - - - - - - - - - DUF2520,F420_oxidored,Rossmann-like k141_288_3 1453501.JELR01000001_gene1907 1.08e-132 382.0 COG0566@1|root,COG0566@2|Bacteria,1MWCM@1224|Proteobacteria,1RY7P@1236|Gammaproteobacteria,4667M@72275|Alteromonadaceae 1236|Gammaproteobacteria J RNA 2'-O ribose methyltransferase substrate binding - - 2.1.1.185 ko:K03218 - - - - ko00000,ko01000,ko03009 - - - SpoU_methylase,SpoU_sub_bind k141_2609_1 218284.CCDN010000005_gene3197 3.2e-147 435.0 COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,4H9T9@91061|Bacilli,1ZBH0@1386|Bacillus 91061|Bacilli S YhgE Pip N-terminal domain protein yhgE - - ko:K01421 - - - - ko00000 - - - ABC2_membrane_3,DUF3533 k141_19187_1 1322246.BN4_10402 4.16e-57 198.0 COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,42NJD@68525|delta/epsilon subdivisions,2WJFK@28221|Deltaproteobacteria,2M7U6@213115|Desulfovibrionales 28221|Deltaproteobacteria O Belongs to the peptidase S16 family - - 3.4.21.53 ko:K01338,ko:K04076,ko:K04770 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - AAA_32,Lon_C k141_4929_1 218284.CCDN010000002_gene1990 4.75e-44 151.0 COG0150@1|root,COG0150@2|Bacteria,1TP9J@1239|Firmicutes,4HABW@91061|Bacilli,1ZBPS@1386|Bacillus 91061|Bacilli F Phosphoribosylformylglycinamidine cyclo-ligase purM - 6.3.3.1 ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04208 RC01100 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C k141_4929_2 218284.CCDN010000002_gene1989 3.83e-159 456.0 COG0034@1|root,COG0034@2|Bacteria,1TPH3@1239|Firmicutes,4HAXU@91061|Bacilli,1ZCE0@1386|Bacillus 91061|Bacilli F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine purF - 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 - - iSB619.SA_RS05225 GATase_6,GATase_7,Pribosyltran k141_26410_1 1116375.VEJY3_16721 4e-23 97.1 COG0833@1|root,COG0833@2|Bacteria,1QU71@1224|Proteobacteria,1T1PB@1236|Gammaproteobacteria,1XV6A@135623|Vibrionales 135623|Vibrionales E Amino acid permease - - - ko:K16238 - - - - ko00000,ko02000 2.A.3.5 - - AA_permease_2 k141_26410_2 1056512.D515_04877 3.62e-94 276.0 COG0225@1|root,COG0225@2|Bacteria,1RCQP@1224|Proteobacteria,1S2S1@1236|Gammaproteobacteria,1XWVM@135623|Vibrionales 135623|Vibrionales C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine - - 1.8.4.11 ko:K07304 - - - - ko00000,ko01000 - - - PMSR k141_26410_3 1116375.VEJY3_16731 3.28e-78 233.0 COG3324@1|root,COG3324@2|Bacteria,1N0AD@1224|Proteobacteria,1S8YM@1236|Gammaproteobacteria,1XY2Z@135623|Vibrionales 135623|Vibrionales S Glyoxalase-like domain - - - ko:K06996 - - - - ko00000 - - - Glyoxalase k141_26410_4 223926.28808471 0.0 944.0 COG0753@1|root,COG0753@2|Bacteria,1MUXZ@1224|Proteobacteria,1RNE7@1236|Gammaproteobacteria,1XSNK@135623|Vibrionales 135623|Vibrionales P Belongs to the catalase family katB GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070887,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1990748 1.11.1.6 ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 M00532 R00009,R00602,R02670 RC00034,RC00767,RC02141,RC02755 ko00000,ko00001,ko00002,ko01000 - - - Catalase,Catalase-rel k141_26410_5 223926.28808472 1.72e-86 256.0 COG0666@1|root,COG0666@2|Bacteria,1RE5N@1224|Proteobacteria,1SDYC@1236|Gammaproteobacteria,1XW17@135623|Vibrionales 135623|Vibrionales S COG0666 FOG Ankyrin repeat - - - ko:K06867 - - - - ko00000 - - - Ank_2,Ank_4,Ank_5 k141_26410_6 1116375.VEJY3_16736 6.12e-147 414.0 COG1335@1|root,COG1335@2|Bacteria,1MUGW@1224|Proteobacteria,1S27G@1236|Gammaproteobacteria,1XTZ1@135623|Vibrionales 135623|Vibrionales Q COG1335 Amidases related to nicotinamidase - - 3.5.1.19 ko:K08281 ko00760,ko01100,map00760,map01100 - R01268 RC00100 ko00000,ko00001,ko01000 - - - Isochorismatase k141_26410_7 223926.28808474 1.19e-174 486.0 COG1051@1|root,COG1051@2|Bacteria,1QTT4@1224|Proteobacteria,1RQ35@1236|Gammaproteobacteria,1XUIX@135623|Vibrionales 135623|Vibrionales F COG1051 ADP-ribose pyrophosphatase - - - - - - - - - - - - NUDIX k141_23959_1 945550.VISI1226_07138 8.99e-07 52.0 COG4655@1|root,COG4655@2|Bacteria,1R8E5@1224|Proteobacteria,1T3RN@1236|Gammaproteobacteria,1Y36H@135623|Vibrionales 135623|Vibrionales S Putative Flp pilus-assembly TadE/G-like - - - - - - - - - - - - Tad k141_23959_2 1051646.VITU9109_21844 1.7e-24 99.8 COG4961@1|root,COG4961@2|Bacteria,1NCGE@1224|Proteobacteria,1SDQ1@1236|Gammaproteobacteria,1XXZS@135623|Vibrionales 135623|Vibrionales U TadE-like protein - - - - - - - - - - - - TadE k141_25160_1 1294265.JCM21738_3824 5.15e-114 328.0 COG0398@1|root,COG0398@2|Bacteria,1TS5T@1239|Firmicutes,4HDKU@91061|Bacilli,1ZCHZ@1386|Bacillus 91061|Bacilli S SNARE associated Golgi protein yhjE - - - - - - - - - - - SNARE_assoc k141_21643_1 218284.CCDN010000001_gene767 1.16e-134 387.0 COG0761@1|root,COG0761@2|Bacteria,1UHT7@1239|Firmicutes,4H9S4@91061|Bacilli,1ZAUG@1386|Bacillus 91061|Bacilli IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis ispH - 1.17.7.4 ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05884,R08210 RC01137,RC01487 ko00000,ko00001,ko00002,ko01000 - - - LYTB k141_7367_1 866895.HBHAL_1566 1.88e-106 319.0 COG2866@1|root,COG2866@2|Bacteria,1V09S@1239|Firmicutes,4HBF2@91061|Bacilli,3NFXX@45667|Halobacillus 91061|Bacilli E Protein of unknown function (DUF2817) - - - - - - - - - - - - DUF2817 k141_12146_1 279010.BL00852 1.22e-203 581.0 COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,4HAJB@91061|Bacilli,1ZBEU@1386|Bacillus 91061|Bacilli O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins ftsH GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0030428,GO:0032502,GO:0042623,GO:0043170,GO:0043934,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - ko:K03798 - M00742 - - ko00000,ko00002,ko01000,ko01002,ko03110 - - - AAA,FtsH_ext,Peptidase_M41 k141_35840_1 930169.B5T_03258 5.4e-94 296.0 COG3509@1|root,COG3509@2|Bacteria,1R66H@1224|Proteobacteria,1SZAS@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q Esterase PHB depolymerase - - - - - - - - - - - - Esterase_phd k141_28804_1 218284.CCDN010000001_gene1154 4.36e-15 70.1 2C8E7@1|root,32RKZ@2|Bacteria,1VIES@1239|Firmicutes,4HKFC@91061|Bacilli,1ZITF@1386|Bacillus 91061|Bacilli S Bacterial domain of unknown function (DUF1798) yppE - - - - - - - - - - - DUF1798 k141_18115_1 674977.VMC_41500 1.09e-179 508.0 COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,1RP5K@1236|Gammaproteobacteria,1XTZJ@135623|Vibrionales 135623|Vibrionales J Belongs to the class-I aminoacyl-tRNA synthetase family cysS GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 ko:K01883 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_2,tRNA-synt_1e,tRNA-synt_1g k141_33491_1 1397699.JNIS01000001_gene2476 4.62e-50 163.0 COG5437@1|root,COG5437@2|Bacteria,1VFXV@1239|Firmicutes,4HNWZ@91061|Bacilli 91061|Bacilli S Phage tail tube protein - - - - - - - - - - - - Phage_tail_2 k141_30037_1 218284.CCDN010000002_gene2708 2.9e-09 55.5 COG1131@1|root,COG1131@2|Bacteria,1TPMQ@1239|Firmicutes,4IPMF@91061|Bacilli,1ZRD4@1386|Bacillus 91061|Bacilli V AAA domain, putative AbiEii toxin, Type IV TA system - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 k141_30037_2 218284.CCDN010000002_gene2709 3.37e-162 456.0 COG0842@1|root,COG0842@2|Bacteria,1UYEB@1239|Firmicutes,4I8Z1@91061|Bacilli,1ZI4G@1386|Bacillus 91061|Bacilli V ABC-2 type transporter - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane k141_14647_1 1123290.AUDQ01000013_gene1246 2.56e-05 47.0 COG1884@1|root,COG1884@2|Bacteria,1TSVA@1239|Firmicutes,4HDE1@91061|Bacilli,26D1P@186818|Planococcaceae 91061|Bacilli I Methylmalonyl-CoA mutase mutA - 5.4.99.2 ko:K01847 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00373,M00376,M00741 R00833 RC00395 ko00000,ko00001,ko00002,ko01000 - - - MM_CoA_mutase k141_21828_1 1116375.VEJY3_15315 1.17e-93 283.0 COG1652@1|root,COG1652@2|Bacteria,1MUBV@1224|Proteobacteria,1RPMB@1236|Gammaproteobacteria,1XUKE@135623|Vibrionales 135623|Vibrionales C protein containing LysM domain - - - - - - - - - - - - LysM k141_12460_1 1279017.AQYJ01000023_gene3141 2.35e-183 515.0 COG0821@1|root,COG0821@2|Bacteria,1MUAX@1224|Proteobacteria,1RMXZ@1236|Gammaproteobacteria,464MT@72275|Alteromonadaceae 1236|Gammaproteobacteria I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate ispG GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046429,GO:0046490,GO:0046872,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R08689,R10859 RC01486 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b2515,iAPECO1_1312.APECO1_4009,iB21_1397.B21_02369,iBWG_1329.BWG_2279,iE2348C_1286.E2348C_2798,iEC55989_1330.EC55989_2800,iECABU_c1320.ECABU_c28200,iECBD_1354.ECBD_1171,iECB_1328.ECB_02407,iECDH10B_1368.ECDH10B_2681,iECDH1ME8569_1439.ECDH1ME8569_2442,iECDH1ME8569_1439.EcDH1_1153,iECD_1391.ECD_02407,iECED1_1282.ECED1_2946,iECH74115_1262.ECH74115_3740,iECIAI39_1322.ECIAI39_2716,iECNA114_1301.ECNA114_2593,iECO103_1326.ECO103_3032,iECO111_1330.ECO111_3239,iECO26_1355.ECO26_3562,iECOK1_1307.ECOK1_2863,iECP_1309.ECP_2520,iECS88_1305.ECS88_2691,iECSE_1348.ECSE_2801,iECSF_1327.ECSF_2359,iECSP_1301.ECSP_3455,iECW_1372.ECW_m2740,iECs_1301.ECs3377,iEKO11_1354.EKO11_1218,iETEC_1333.ETEC_2672,iEcDH1_1363.EcDH1_1153,iEcE24377_1341.EcE24377A_2799,iEcolC_1368.EcolC_1162,iJO1366.b2515,iJR904.b2515,iLF82_1304.LF82_1130,iNRG857_1313.NRG857_12515,iUMN146_1321.UM146_04130,iUMNK88_1353.UMNK88_3165,iUTI89_1310.UTI89_C2836,iWFL_1372.ECW_m2740,iY75_1357.Y75_RS13130,iYL1228.KPN_02845,iZ_1308.Z3778,ic_1306.c3037 GcpE k141_27627_1 1279017.AQYJ01000026_gene245 1.3e-121 363.0 COG0596@1|root,COG0596@2|Bacteria,1R6KU@1224|Proteobacteria,1RZA4@1236|Gammaproteobacteria 1236|Gammaproteobacteria S hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_4 k141_1556_1 1295642.H839_16098 2.89e-36 137.0 COG1196@1|root,COG1196@2|Bacteria,1TQY7@1239|Firmicutes,4HCRF@91061|Bacilli 91061|Bacilli D Psort location Cytoplasmic, score - - - - - - - - - - - - AAA_23,AAA_27 k141_1556_2 574376.BAMA_15555 6.5e-70 226.0 COG3723@1|root,COG3723@2|Bacteria,1U245@1239|Firmicutes,4IBMP@91061|Bacilli,1ZH4C@1386|Bacillus 91061|Bacilli L RecT family - - - ko:K07455 - - - - ko00000,ko03400 - - - RecT k141_32407_1 1453501.JELR01000001_gene2198 7.39e-104 327.0 COG1330@1|root,COG2887@1|root,COG1330@2|Bacteria,COG2887@2|Bacteria,1QVX1@1224|Proteobacteria,1RP9I@1236|Gammaproteobacteria,465DQ@72275|Alteromonadaceae 1236|Gammaproteobacteria L PD-(D/E)XK nuclease superfamily lidB - - - - - - - - - - - PDDEXK_1 k141_556_1 1403313.AXBR01000015_gene2135 5.75e-42 154.0 COG0737@1|root,COG0737@2|Bacteria,1TPV2@1239|Firmicutes,4HB9S@91061|Bacilli,1ZAY0@1386|Bacillus 91061|Bacilli F Belongs to the 5'-nucleotidase family - - 3.1.3.5,3.1.3.6,3.1.4.16,3.6.1.45 ko:K01081,ko:K01119,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01562,R01569,R01664,R01877,R01968,R02088,R02102,R02148,R02323,R02370,R02719,R03346,R03537,R03538,R03929,R05135 RC00017,RC00078,RC00296 ko00000,ko00001,ko01000 - - - 5_nucleotid_C,CW_binding_1,Gram_pos_anchor,Metallophos,SLH k141_13648_5 1116375.VEJY3_02625 0.0 1255.0 COG4590@1|root,COG4590@2|Bacteria,1QTTD@1224|Proteobacteria,1T1GK@1236|Gammaproteobacteria,1XSKV@135623|Vibrionales 135623|Vibrionales P phosphate ABC transporter, permease - - - ko:K02037 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 k141_13648_6 1116375.VEJY3_02620 0.0 1065.0 COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,1RNRX@1236|Gammaproteobacteria,1XSGM@135623|Vibrionales 135623|Vibrionales F Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) ppk GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008976,GO:0009358,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0032991,GO:0044237,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.4.1 ko:K00937 ko00190,ko03018,map00190,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - PP_kinase,PP_kinase_C,PP_kinase_N k141_9996_2 1280944.HY17_15130 4.36e-09 57.8 2CM4P@1|root,32SDP@2|Bacteria,1N3I5@1224|Proteobacteria,2UDS1@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_31311_2 1279017.AQYJ01000019_gene1511 1.53e-50 165.0 COG4968@1|root,COG4968@2|Bacteria,1N6QE@1224|Proteobacteria,1SCBS@1236|Gammaproteobacteria,467AA@72275|Alteromonadaceae 1236|Gammaproteobacteria NU COG4968 Tfp pilus assembly protein PilE pilE - - ko:K02655 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - ComP_DUS,N_methyl k141_36006_1 218284.CCDN010000001_gene465 2.47e-117 345.0 COG0823@1|root,COG0823@2|Bacteria,1UZMN@1239|Firmicutes,4HBYS@91061|Bacilli,1ZEJZ@1386|Bacillus 91061|Bacilli U Involved in the tonB-independent uptake of proteins - - - - - - - - - - - - PD40 k141_6463_2 1089455.MOPEL_020_00510 3.26e-32 124.0 COG3279@1|root,COG3279@2|Bacteria,2GKK5@201174|Actinobacteria,4F67H@85018|Dermatophilaceae 201174|Actinobacteria K LytTr DNA-binding domain - - - - - - - - - - - - LytTR,Response_reg k141_8821_2 1453501.JELR01000001_gene2208 6.09e-35 121.0 COG2168@1|root,COG2168@2|Bacteria,1NGF3@1224|Proteobacteria,1SGPI@1236|Gammaproteobacteria,468W2@72275|Alteromonadaceae 1236|Gammaproteobacteria P DsrH like protein tusB GO:0002097,GO:0002098,GO:0002143,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1902494,GO:1990228,GO:1990234 - ko:K07237 ko04122,map04122 - - - ko00000,ko00001,ko03016 - - - DsrH k141_8821_3 1279017.AQYJ01000029_gene3742 1.21e-47 155.0 COG2923@1|root,COG2923@2|Bacteria,1N8RV@1224|Proteobacteria,1SD0S@1236|Gammaproteobacteria,468Z9@72275|Alteromonadaceae 1236|Gammaproteobacteria P protein involved in the oxidation of intracellular sulfur tusC GO:0002097,GO:0002098,GO:0002143,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1902494,GO:1990228,GO:1990234 - ko:K07236 ko04122,map04122 - - - ko00000,ko00001,ko03016 - - - DrsE k141_8821_4 1453501.JELR01000001_gene2210 7.21e-63 195.0 COG1553@1|root,COG1553@2|Bacteria,1N021@1224|Proteobacteria,1S99J@1236|Gammaproteobacteria,467M1@72275|Alteromonadaceae 1236|Gammaproteobacteria P conserved protein involved in intracellular sulfur reduction tusD GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0019417,GO:0032991,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055114,GO:0071704,GO:0090304,GO:0097163,GO:0140104,GO:1901360,GO:1902494,GO:1990228,GO:1990234 - ko:K07235 ko04122,map04122 - - - ko00000,ko00001,ko01000,ko03016 - - - DrsE k141_8821_5 1453501.JELR01000001_gene2211 5.78e-129 370.0 COG0670@1|root,COG0670@2|Bacteria,1MU69@1224|Proteobacteria,1RRVZ@1236|Gammaproteobacteria,4653K@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the BI1 family yccA GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016021,GO:0019222,GO:0030162,GO:0031224,GO:0044425,GO:0044464,GO:0050789,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071944,GO:0080090 - ko:K19416 - M00742 - - ko00000,ko00002,ko02000 1.A.14.2.1 - - Bax1-I k141_8821_6 1042377.AFPJ01000009_gene193 0.0 978.0 COG3568@1|root,COG3568@2|Bacteria,1R977@1224|Proteobacteria,1RTF2@1236|Gammaproteobacteria,466AF@72275|Alteromonadaceae 1236|Gammaproteobacteria L Type I phosphodiesterase / nucleotide pyrophosphatase - - - - - - - - - - - - Exo_endo_phos,Phosphodiest k141_8821_7 1453501.JELR01000001_gene2213 7.07e-204 576.0 COG0438@1|root,COG0438@2|Bacteria,1MUB7@1224|Proteobacteria,1RZ4V@1236|Gammaproteobacteria,465TN@72275|Alteromonadaceae 1236|Gammaproteobacteria M Glycosyl transferase 4-like domain - - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_2,Glyco_transf_4,Glycos_transf_1 k141_8821_8 1042377.AFPJ01000009_gene191 6.25e-132 397.0 COG3387@1|root,COG3387@2|Bacteria,1MW9J@1224|Proteobacteria,1T2G2@1236|Gammaproteobacteria,465X7@72275|Alteromonadaceae 1236|Gammaproteobacteria G PFAM Glycoside hydrolase 15-related - - - - - - - - - - - - F5_F8_type_C,GDE_C k141_27639_1 1279017.AQYJ01000021_gene2828 7.04e-15 72.0 COG0494@1|root,COG0494@2|Bacteria,1RD2C@1224|Proteobacteria,1SA4Q@1236|Gammaproteobacteria,467P1@72275|Alteromonadaceae 1236|Gammaproteobacteria L NUDIX domain - - - - - - - - - - - - NUDIX k141_27639_2 1279017.AQYJ01000021_gene2827 1.82e-202 594.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,466AN@72275|Alteromonadaceae 1236|Gammaproteobacteria V AcrB/AcrD/AcrF family bepG - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran k141_23122_1 1294265.JCM21738_1219 9.58e-56 175.0 COG5496@1|root,COG5496@2|Bacteria,1UH3T@1239|Firmicutes,4HJC5@91061|Bacilli,1ZI8A@1386|Bacillus 91061|Bacilli S Thioesterase - - - - - - - - - - - - 4HBT k141_9997_1 1071073.KI530537_gene2668 1.01e-50 172.0 COG3173@1|root,COG3173@2|Bacteria,1V4AG@1239|Firmicutes 1239|Firmicutes S Aminoglycoside phosphotransferase - - - - - - - - - - - - APH k141_9997_2 1121929.KB898669_gene3207 4.54e-46 151.0 COG0346@1|root,COG0346@2|Bacteria,1V422@1239|Firmicutes,4HH25@91061|Bacilli,471TT@74385|Gracilibacillus 91061|Bacilli E Glyoxalase-like domain fosB GO:0003674,GO:0003824,GO:0004364,GO:0008150,GO:0016740,GO:0016765,GO:0042221,GO:0046677,GO:0050896 - ko:K11210,ko:K21252 - - - - ko00000,ko01000,ko01504 - - - Glyoxalase k141_573_1 1453501.JELR01000002_gene45 3.89e-37 137.0 COG0554@1|root,COG0554@2|Bacteria,1MUP7@1224|Proteobacteria,1RMAF@1236|Gammaproteobacteria,464DH@72275|Alteromonadaceae 1236|Gammaproteobacteria C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate glpK GO:0003674,GO:0003824,GO:0004370,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019405,GO:0019563,GO:0019751,GO:0033554,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046164,GO:0046174,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:1901575,GO:1901615,GO:1901616 2.7.1.30 ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 - R00847 RC00002,RC00017 ko00000,ko00001,ko01000,ko04147 - - iE2348C_1286.E2348C_4230,iECNA114_1301.ECNA114_4065,iECSF_1327.ECSF_3786 FGGY_C,FGGY_N k141_33769_1 218284.CCDN010000001_gene205 9.95e-49 173.0 2E0HP@1|root,32W3F@2|Bacteria,1VAMS@1239|Firmicutes,4HNFF@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - k141_21838_1 1117647.M5M_16770 1.34e-172 489.0 COG1609@1|root,COG1609@2|Bacteria,1MVUR@1224|Proteobacteria,1RN8T@1236|Gammaproteobacteria,1J5VD@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria K helix_turn _helix lactose operon repressor - - - ko:K05499 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 k141_21838_2 1117647.M5M_16775 0.0 930.0 COG0591@1|root,COG0591@2|Bacteria,1PNHU@1224|Proteobacteria,1S0S6@1236|Gammaproteobacteria,1JAYJ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - - - - - - - - - - SSF k141_21838_3 498211.CJA_0242 4.06e-221 617.0 COG2152@1|root,COG2152@2|Bacteria,1MX8M@1224|Proteobacteria,1RYFR@1236|Gammaproteobacteria,1FG0T@10|Cellvibrio 1236|Gammaproteobacteria G Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose - - 2.4.1.281 ko:K16212 - - R09943 RC00049 ko00000,ko01000 - - - Glyco_hydro_130 k141_21838_4 1117647.M5M_16785 2.57e-147 431.0 COG2942@1|root,COG2942@2|Bacteria,1P7CS@1224|Proteobacteria,1S0PA@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Catalyzes the reversible epimerization of cellobiose to 4-O-beta-D-glucopyranosyl-D-mannose (Glc-Man) unk2 - 5.1.3.11 ko:K16213 - - R01445,R10810 RC00289 ko00000,ko01000 - - - GlcNAc_2-epim k141_21838_5 1117647.M5M_16790 1.45e-151 444.0 COG3934@1|root,COG3934@2|Bacteria,1R6H5@1224|Proteobacteria,1RPMT@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Pkd domain containing protein - - - - - - - - - - - - CBM_35,Cellulase k141_12488_1 1294265.JCM21738_4048 1.08e-69 221.0 COG0849@1|root,COG0849@2|Bacteria,1TP1Z@1239|Firmicutes,4H9NF@91061|Bacilli,1ZBH1@1386|Bacillus 91061|Bacilli D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring ftsA GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032153,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0098552,GO:0098562 - ko:K03590 ko04112,map04112 - - - ko00000,ko00001,ko03036,ko04812 - - - DUF3484,FtsA,SHS2_FTSA k141_12488_2 1196031.ALEG01000039_gene1565 3.11e-15 73.9 COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,4H9WZ@91061|Bacilli,1ZC2F@1386|Bacillus 91061|Bacilli D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity ftsZ GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030428,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03531 ko04112,map04112 - - - ko00000,ko00001,ko02048,ko03036,ko04812 - - - FtsZ_C,Tubulin k141_28957_1 218284.CCDN010000002_gene1988 1.08e-172 501.0 COG0046@1|root,COG0046@2|Bacteria,1TPAS@1239|Firmicutes,4HB3N@91061|Bacilli,1ZCN8@1386|Bacillus 91061|Bacilli F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL purL GO:0003674,GO:0003824,GO:0004642,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C k141_15868_1 218284.CCDN010000005_gene3476 2.53e-191 536.0 COG1979@1|root,COG1979@2|Bacteria,1TPS3@1239|Firmicutes,4H9TR@91061|Bacilli,1ZBKF@1386|Bacillus 91061|Bacilli C oxidoreductases, Fe-dependent alcohol dehydrogenase family yugJ - - ko:K19955 - - - - ko00000,ko01000 - - - Fe-ADH k141_18346_2 218284.CCDN010000005_gene3432 8.62e-148 421.0 COG0614@1|root,COG0614@2|Bacteria,1TQV7@1239|Firmicutes,4HCF3@91061|Bacilli,1ZBF0@1386|Bacillus 91061|Bacilli P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component btuF - - ko:K02016 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - iYO844.BSU33180 Peripla_BP_2 k141_8822_1 1294265.JCM21738_4698 7.5e-50 161.0 COG0628@1|root,COG0628@2|Bacteria,1TS4S@1239|Firmicutes,4HC6G@91061|Bacilli,1ZBXK@1386|Bacillus 91061|Bacilli S sporulation integral membrane protein YtvI ytvI GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - - - - - - - - - - AI-2E_transport k141_17067_1 377629.TERTU_2988 1.17e-61 196.0 COG0693@1|root,COG0693@2|Bacteria,1N7T2@1224|Proteobacteria,1RSBI@1236|Gammaproteobacteria,2PQ38@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria S DJ-1/PfpI family thiJ GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006464,GO:0006517,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009100,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0019538,GO:0022613,GO:0030091,GO:0033554,GO:0034599,GO:0036211,GO:0036524,GO:0036525,GO:0042026,GO:0042221,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0070887,GO:0071704,GO:0071840,GO:0140096,GO:1901135,GO:1901564 3.5.1.124 ko:K03152 - - - - ko00000,ko01000,ko01002 - - - DJ-1_PfpI k141_23124_1 156889.Mmc1_1066 1.04e-29 115.0 COG1999@1|root,COG1999@2|Bacteria,1RHJ8@1224|Proteobacteria,2U0Q3@28211|Alphaproteobacteria 28211|Alphaproteobacteria S protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems - - - ko:K07152 - - - - ko00000,ko03029 - - - SCO1-SenC k141_12489_1 1278073.MYSTI_02331 9.64e-38 137.0 COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,42M67@68525|delta/epsilon subdivisions,2WJQX@28221|Deltaproteobacteria,2YTX6@29|Myxococcales 28221|Deltaproteobacteria E Cys Met metabolism metC - 2.5.1.48,4.4.1.1,4.4.1.8 ko:K01739,ko:K01758,ko:K01760 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017,M00338 R00782,R00999,R01001,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04941,R04944,R04945,R04946,R09366 RC00020,RC00056,RC00069,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Cys_Met_Meta_PP k141_27640_1 866895.HBHAL_4886 8.59e-88 286.0 COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,4HABE@91061|Bacilli,3NDEF@45667|Halobacillus 91061|Bacilli EF Carbamoyl-phosphate synthetase large chain, oligomerisation domain carB GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS k141_21839_1 218284.CCDN010000008_gene4259 6.88e-11 60.8 COG0671@1|root,COG0671@2|Bacteria,1V2ZH@1239|Firmicutes,4HMGP@91061|Bacilli,1ZRR2@1386|Bacillus 91061|Bacilli I PAP2 superfamily - - - - - - - - - - - - PAP2,PAP2_3 k141_575_1 2074.JNYD01000036_gene5351 3.01e-10 65.5 COG0477@1|root,COG2814@2|Bacteria,2I2EY@201174|Actinobacteria,4DY4V@85010|Pseudonocardiales 201174|Actinobacteria EGP Arabinose efflux permease family protein - - - - - - - - - - - - MFS_3 k141_1578_1 218284.CCDN010000005_gene3406 3.76e-174 489.0 COG0739@1|root,COG0739@2|Bacteria,1TQMQ@1239|Firmicutes,4HC7V@91061|Bacilli,1ZAQT@1386|Bacillus 91061|Bacilli M Peptidase, M23 lytH - - ko:K21472 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_M23 k141_2783_2 42565.FP66_06480 1.08e-36 136.0 COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,1RNSZ@1236|Gammaproteobacteria,1XH4H@135619|Oceanospirillales 135619|Oceanospirillales J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome fusA - - ko:K02355 - - - - ko00000,ko03012,ko03029 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 k141_31312_2 218284.CCDN010000003_gene2988 1.49e-49 157.0 2EJ4H@1|root,33CVR@2|Bacteria,1VMIU@1239|Firmicutes,4HP24@91061|Bacilli,1ZJ5B@1386|Bacillus 91061|Bacilli S Peptide ABC transporter permease yabK - - - - - - - - - - - DUF2757 k141_25464_1 218284.CCDN010000001_gene1225 1e-82 253.0 COG0515@1|root,COG0515@2|Bacteria,1UZEH@1239|Firmicutes,4IPW7@91061|Bacilli,1ZRE1@1386|Bacillus 91061|Bacilli KLT Protein tyrosine kinase - - 2.7.11.1 ko:K08884 - - - - ko00000,ko01000,ko01001 - - - Pkinase k141_33771_1 1305836.AXVE01000012_gene67 9.07e-90 281.0 COG0167@1|root,COG0167@2|Bacteria,1TRFE@1239|Firmicutes,4HDHX@91061|Bacilli,26GPT@186818|Planococcaceae 91061|Bacilli F Dihydroorotate dehydrogenase - - 1.3.5.2 ko:K00254 ko00240,ko01100,map00240,map01100 M00051 R01868 RC00051 ko00000,ko00001,ko00002,ko01000 - - - DHO_dh k141_12490_1 218284.CCDN010000002_gene2222 1.18e-26 98.2 2BGZ1@1|root,32AZ5@2|Bacteria,1UB27@1239|Firmicutes,4IMF3@91061|Bacilli,1ZK06@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_12490_2 218284.CCDN010000002_gene2223 1.07e-47 165.0 COG0840@1|root,COG0840@2|Bacteria,1V0SD@1239|Firmicutes,4HD8P@91061|Bacilli,1ZCT0@1386|Bacillus 91061|Bacilli NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - MCPsignal k141_30059_1 218284.CCDN010000005_gene3310 3.29e-108 320.0 COG0332@1|root,COG0332@2|Bacteria,1TPDE@1239|Firmicutes,4H9W9@91061|Bacilli,1ZAW8@1386|Bacillus 91061|Bacilli I Stage V sporulation protein AD spoVAD - - ko:K06406 - - - - ko00000 - - - SpoVAD k141_23126_1 448385.sce0875 1.37e-66 216.0 COG0677@1|root,COG0677@2|Bacteria,1MUC6@1224|Proteobacteria,42M4F@68525|delta/epsilon subdivisions,2WKK3@28221|Deltaproteobacteria,2Z320@29|Myxococcales 28221|Deltaproteobacteria M Belongs to the UDP-glucose GDP-mannose dehydrogenase family - - 1.1.1.136 ko:K02474,ko:K13015 ko00520,map00520 - R00421,R06894 RC00291 ko00000,ko00001,ko01000,ko01005 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N k141_18347_2 1294265.JCM21738_5429 3.37e-110 318.0 COG1247@1|root,COG1247@2|Bacteria,1VAAC@1239|Firmicutes,4HKUR@91061|Bacilli,1ZHWJ@1386|Bacillus 91061|Bacilli M FR47-like protein - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10,FR47 k141_18347_3 1294265.JCM21738_5430 1.5e-11 63.2 COG0697@1|root,COG0697@2|Bacteria,1TR1G@1239|Firmicutes,4HB57@91061|Bacilli,1ZCN9@1386|Bacillus 91061|Bacilli EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - - - - - - - - - - EamA k141_36008_1 218284.CCDN010000002_gene2269 9.64e-61 194.0 COG0122@1|root,COG0122@2|Bacteria,1TQAF@1239|Firmicutes,4HBYM@91061|Bacilli,1ZCV5@1386|Bacillus 91061|Bacilli L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase yfjP GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003824,GO:0003905,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008725,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0032131,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0043733,GO:0043916,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.2.2.21 ko:K01247 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - HhH-GPD k141_15870_1 218284.CCDN010000002_gene2085 4.29e-78 232.0 COG3460@1|root,COG3460@2|Bacteria,1V6J5@1239|Firmicutes,4HJ49@91061|Bacilli,1ZH3H@1386|Bacillus 91061|Bacilli Q Phenylacetic acid degradation B paaB - - ko:K02610 ko00360,ko01120,map00360,map01120 - R09838 RC02690 ko00000,ko00001 - - - PaaB k141_5230_1 218284.CCDN010000001_gene786 1.58e-103 309.0 COG0477@1|root,COG0477@2|Bacteria,1TTC8@1239|Firmicutes,4HAPZ@91061|Bacilli,1ZAQ7@1386|Bacillus 91061|Bacilli EGP Major facilitator superfamily yqgE - - ko:K08222 - - - - ko00000,ko02000 2.A.1.33 - - MFS_1 k141_24172_1 1116375.VEJY3_07310 1.41e-92 278.0 COG5473@1|root,COG5473@2|Bacteria,1N3T0@1224|Proteobacteria,1SEVY@1236|Gammaproteobacteria,1XTIE@135623|Vibrionales 135623|Vibrionales - - VP1530 - - - - - - - - - - - - k141_24172_2 1116375.VEJY3_07315 3.4e-136 388.0 28IUI@1|root,2Z8T7@2|Bacteria,1RHAD@1224|Proteobacteria,1S11Z@1236|Gammaproteobacteria,1XUK1@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF2987) VV1682 - - - - - - - - - - - DUF2987 k141_24172_3 1280001.BAOA01000077_gene3124 5.76e-46 155.0 COG0037@1|root,COG0037@2|Bacteria,1MW5Q@1224|Proteobacteria,1RN2H@1236|Gammaproteobacteria,1XTQ4@135623|Vibrionales 135623|Vibrionales J Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system ttcA - - ko:K14058 - - - - ko00000,ko03016 - - - ATP_bind_3 k141_2784_1 1453501.JELR01000002_gene199 1.92e-118 350.0 COG0738@1|root,COG0738@2|Bacteria,1MXDC@1224|Proteobacteria,1RMQJ@1236|Gammaproteobacteria,4654I@72275|Alteromonadaceae 1236|Gammaproteobacteria G Major Facilitator Superfamily gluP - - ko:K02429 - - - - ko00000,ko02000 2.A.1.7 - - MFS_1 k141_33773_2 1453501.JELR01000001_gene2313 7.83e-28 110.0 COG0007@1|root,COG1648@1|root,COG0007@2|Bacteria,COG1648@2|Bacteria,1MUI0@1224|Proteobacteria,1RM9V@1236|Gammaproteobacteria,4645Q@72275|Alteromonadaceae 1236|Gammaproteobacteria H Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme cysG - 1.3.1.76,2.1.1.107,4.99.1.4 ko:K02302,ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02864,R03194,R03947 RC00003,RC00871,RC01012,RC01034 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_3999 CysG_dimeriser,NAD_binding_7,Sirohm_synth_M,TP_methylase k141_11180_2 1279017.AQYJ01000028_gene2511 0.0 1428.0 COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,1RPIU@1236|Gammaproteobacteria,46439@72275|Alteromonadaceae 1236|Gammaproteobacteria F COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ) carB GO:0000050,GO:0000166,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016053,GO:0016597,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b0033,iBWG_1329.BWG_0031,iECDH10B_1368.ECDH10B_0034,iECDH1ME8569_1439.ECDH1ME8569_0031,iECUMN_1333.ECUMN_0034,iEcDH1_1363.EcDH1_3566,iJN746.PP_4723,iJO1366.b0033,iJR904.b0033,iPC815.YPO0482,iY75_1357.Y75_RS00170,iYL1228.KPN_00041 CPSase_L_D2,CPSase_L_D3,MGS k141_11207_4 1116375.VEJY3_13235 9.67e-209 584.0 COG2265@1|root,COG2265@2|Bacteria,1MV3A@1224|Proteobacteria,1RN1D@1236|Gammaproteobacteria,1XUN9@135623|Vibrionales 135623|Vibrionales J Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA rlmD GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.190 ko:K03215 - - - - ko00000,ko01000,ko03009 - - - TRAM,tRNA_U5-meth_tr k141_6472_1 218284.CCDN010000002_gene2219 1.28e-109 325.0 COG1017@1|root,COG1018@1|root,COG1017@2|Bacteria,COG1018@2|Bacteria,1TRG2@1239|Firmicutes,4HAU3@91061|Bacilli,1ZAP9@1386|Bacillus 91061|Bacilli C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress hmp GO:0000166,GO:0001505,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008941,GO:0009056,GO:0009987,GO:0016491,GO:0016705,GO:0016708,GO:0017144,GO:0033554,GO:0034641,GO:0036094,GO:0042133,GO:0042135,GO:0042737,GO:0043167,GO:0043168,GO:0044237,GO:0044248,GO:0044270,GO:0044464,GO:0046209,GO:0046210,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051213,GO:0051409,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0071500,GO:0071949,GO:0072593,GO:0097159,GO:1901265,GO:1901363,GO:2001057 1.14.12.17,1.18.1.3 ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 M00538 R02550,R03562,R05666,R09513 RC00269,RC00490,RC02556 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_6,Globin,NAD_binding_1 k141_37239_2 935863.AWZR01000004_gene731 5.95e-53 177.0 COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,1RNZZ@1236|Gammaproteobacteria,1X33C@135614|Xanthomonadales 135614|Xanthomonadales F Phosphoribosylformylglycinamidine cyclo-ligase purM - 6.3.3.1 ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04208 RC01100 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C k141_34926_1 1279017.AQYJ01000028_gene2153 9.41e-17 77.0 2EG5Q@1|root,339XK@2|Bacteria,1NGQ6@1224|Proteobacteria,1SHCX@1236|Gammaproteobacteria,46923@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF4168) - - - - - - - - - - - - DUF4168 k141_31329_1 523791.Kkor_0188 2.22e-78 243.0 COG3751@1|root,COG3751@2|Bacteria,1RBXB@1224|Proteobacteria,1RR8W@1236|Gammaproteobacteria 1236|Gammaproteobacteria O SMART Prolyl 4-hydroxylase, alpha subunit - - - - - - - - - - - - 2OG-FeII_Oxy_3 k141_2801_2 218284.CCDN010000009_gene4315 6.25e-188 541.0 COG0601@1|root,COG1173@1|root,COG0601@2|Bacteria,COG1173@2|Bacteria,1V21B@1239|Firmicutes,4HDPU@91061|Bacilli,1ZEQ7@1386|Bacillus 91061|Bacilli EP Binding-protein-dependent transport system inner membrane component - - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1,Peptidase_M1 k141_19488_2 218284.CCDN010000001_gene1803 1.17e-90 273.0 COG0324@1|root,COG0324@2|Bacteria,1TPSC@1239|Firmicutes,4HAVW@91061|Bacilli,1ZBX9@1386|Bacillus 91061|Bacilli J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) miaA GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 - R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 - - - IPPT k141_609_1 171693.BN988_02914 6.7e-50 161.0 COG1051@1|root,COG1051@2|Bacteria,1V3T8@1239|Firmicutes,4HH2F@91061|Bacilli,23KIG@182709|Oceanobacillus 91061|Bacilli F NUDIX domain - - - - - - - - - - - - NUDIX k141_609_2 1234664.AMRO01000038_gene3140 4.52e-11 62.0 COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,1TPXQ@1239|Firmicutes,4HA3C@91061|Bacilli,1WEYS@129337|Geobacillus 91061|Bacilli C Catalyzes the reversible hydration of fumarate to (S)- malate fumA - 4.2.1.2 ko:K01676 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - - Fumerase,Fumerase_C k141_15885_1 1125712.HMPREF1316_0400 1.72e-07 50.8 COG1447@1|root,COG1447@2|Bacteria,2GPKA@201174|Actinobacteria,4CWBA@84998|Coriobacteriia 84998|Coriobacteriia G PTS system, Lactose Cellobiose specific IIA subunit lacF - - - - - - - - - - - PTS_IIA k141_15885_2 4572.TRIUR3_31913-P1 1.95e-103 313.0 COG2723@1|root,KOG0626@2759|Eukaryota,37I38@33090|Viridiplantae,3GC7Z@35493|Streptophyta,3KSAT@4447|Liliopsida,3I8X9@38820|Poales 35493|Streptophyta G Glycosyl hydrolase family 1 - - - - - - - - - - - - Glyco_hydro_1 k141_34927_1 768066.HELO_2917 3.36e-83 248.0 COG3521@1|root,COG3521@2|Bacteria,1MX5E@1224|Proteobacteria,1S83T@1236|Gammaproteobacteria,1XPPW@135619|Oceanospirillales 135619|Oceanospirillales S Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 vasD - - ko:K11906 ko03070,map03070 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - T6SS-SciN k141_34927_2 768066.HELO_2916 6.62e-29 112.0 COG3522@1|root,COG3522@2|Bacteria,1MXKE@1224|Proteobacteria,1RNCB@1236|Gammaproteobacteria,1XHSM@135619|Oceanospirillales 135619|Oceanospirillales S type VI secretion protein, VC_A0114 family - - - ko:K11893 ko02025,map02025 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - T6SS_VasE k141_25490_1 1279017.AQYJ01000028_gene2064 4.25e-15 73.2 COG1714@1|root,COG1714@2|Bacteria,1RIE9@1224|Proteobacteria,1S566@1236|Gammaproteobacteria,467PA@72275|Alteromonadaceae 1236|Gammaproteobacteria S RDD family - - - - - - - - - - - - RDD k141_25490_2 1279017.AQYJ01000028_gene2063 2.08e-136 396.0 COG1300@1|root,COG1300@2|Bacteria,1Q1GN@1224|Proteobacteria,1RR61@1236|Gammaproteobacteria,466VE@72275|Alteromonadaceae 1236|Gammaproteobacteria S Stage II sporulation protein M - - - - - - - - - - - - SpoIIM k141_19742_1 240302.BN982_02922 6.7e-79 261.0 COG0454@1|root,COG0456@2|Bacteria,1TQQA@1239|Firmicutes,4HBXN@91061|Bacilli,3NDP1@45667|Halobacillus 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10 k141_18652_1 391593.RCCS2_06229 1.76e-97 294.0 COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2TQKK@28211|Alphaproteobacteria,2P2ZM@2433|Roseobacter 28211|Alphaproteobacteria P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components ddpB GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02033 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 k141_18652_2 1279038.KB907344_gene3552 7.9e-139 401.0 COG1173@1|root,COG1173@2|Bacteria,1MW3R@1224|Proteobacteria,2TUCW@28211|Alphaproteobacteria,2JPAG@204441|Rhodospirillales 204441|Rhodospirillales EP N-terminal TM domain of oligopeptide transport permease C - - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1,OppC_N k141_18652_3 1279038.KB907344_gene3551 6.35e-114 337.0 COG0444@1|root,COG0444@2|Bacteria,1NTNP@1224|Proteobacteria,2TUKU@28211|Alphaproteobacteria,2JQ6X@204441|Rhodospirillales 204441|Rhodospirillales EP ATPases associated with a variety of cellular activities - - - ko:K02031 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - ABC_tran k141_37436_1 1536772.R70723_31385 1.83e-50 175.0 COG1653@1|root,COG1653@2|Bacteria,1UY8X@1239|Firmicutes,4HT5T@91061|Bacilli,26RVV@186822|Paenibacillaceae 91061|Bacilli G ABC transporter substrate-binding protein - - - ko:K10232 ko02010,map02010 M00201 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.32,3.A.1.1.8 - - SBP_bac_1 k141_13963_1 218284.CCDN010000001_gene1464 8.01e-65 204.0 COG1024@1|root,COG1024@2|Bacteria,1TQ2V@1239|Firmicutes,4HBT0@91061|Bacilli,1ZE3C@1386|Bacillus 91061|Bacilli I Belongs to the enoyl-CoA hydratase isomerase family phaB GO:0003674,GO:0003824,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006635,GO:0006636,GO:0008150,GO:0008152,GO:0008610,GO:0009056,GO:0009058,GO:0009062,GO:0009987,GO:0016042,GO:0016053,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016860,GO:0016863,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0033559,GO:0034017,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:0072330,GO:1901575,GO:1901576 5.3.3.14,5.3.3.18 ko:K15866,ko:K18474 ko00061,ko00360,ko01120,map00061,map00360,map01120 - R07639,R09837,R09839 RC00004,RC00326,RC01078,RC02689,RC03003 ko00000,ko00001,ko01000,ko01004 - - - ECH_1 k141_13963_2 218284.CCDN010000001_gene1463 8.37e-39 138.0 COG3173@1|root,COG3173@2|Bacteria,1TSCJ@1239|Firmicutes,4HB2X@91061|Bacilli,1ZBDG@1386|Bacillus 91061|Bacilli S Phosphotransferase enzyme family - - - - - - - - - - - - APH k141_4242_1 997296.PB1_01410 1.41e-33 124.0 COG0167@1|root,COG0167@2|Bacteria,1TPFV@1239|Firmicutes,4HA5H@91061|Bacilli,1ZBNC@1386|Bacillus 91061|Bacilli F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily pyrD GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14 ko:K17828 ko00240,ko01100,map00240,map01100 M00051 R01869 RC00051 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU15540 DHO_dh k141_4242_2 218284.CCDN010000001_gene55 2.16e-124 359.0 COG0284@1|root,COG0284@2|Bacteria,1TPPH@1239|Firmicutes,4HAJ2@91061|Bacilli,1ZB1I@1386|Bacillus 91061|Bacilli F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) pyrF GO:0003674,GO:0003824,GO:0004590,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 ko:K01591 ko00240,ko01100,map00240,map01100 M00051 R00965 RC00409 ko00000,ko00001,ko00002,ko01000 - - - OMPdecase k141_11510_1 926550.CLDAP_25210 3.18e-36 134.0 COG2335@1|root,COG2335@2|Bacteria,2G7AJ@200795|Chloroflexi 200795|Chloroflexi M Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - - - - - - - - - - Fasciclin k141_1759_1 1337093.MBE-LCI_2853 1.24e-20 91.3 COG0491@1|root,COG0491@2|Bacteria,1MVC3@1224|Proteobacteria,2TUAZ@28211|Alphaproteobacteria,2P8B2@245186|Loktanella 28211|Alphaproteobacteria S Metallo-beta-lactamase superfamily - - 3.1.2.6 ko:K01069 ko00620,map00620 - R01736 RC00004,RC00137 ko00000,ko00001,ko01000 - - - Lactamase_B k141_30234_2 1042377.AFPJ01000008_gene1957 7.17e-213 602.0 COG0654@1|root,COG0654@2|Bacteria,1NSGN@1224|Proteobacteria,1T22A@1236|Gammaproteobacteria,46D2U@72275|Alteromonadaceae 1236|Gammaproteobacteria CH Tryptophan halogenase - - 1.14.19.9 ko:K14266 ko00404,ko01130,map00404,map01130 M00789,M00790 R09570 RC00949 ko00000,ko00001,ko00002,ko01000 - - - Trp_halogenase k141_9074_1 634956.Geoth_1029 4.92e-07 51.2 COG1994@1|root,COG1994@2|Bacteria,1V72P@1239|Firmicutes,4IR6Y@91061|Bacilli,1WE7E@129337|Geobacillus 91061|Bacilli S Peptidase family M50 spoIVFB - - ko:K06402 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M50,Peptidase_M50B k141_32657_1 218284.CCDN010000001_gene1821 8.2e-210 580.0 COG0388@1|root,COG0388@2|Bacteria,1TRMU@1239|Firmicutes,4HCTJ@91061|Bacilli,1ZEMV@1386|Bacillus 91061|Bacilli S Carbon-nitrogen hydrolase - - 3.5.1.6 ko:K01431 ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100 M00046 R00905,R04666,R08228 RC00096 ko00000,ko00001,ko00002,ko01000 - - - CN_hydrolase k141_23403_1 1453501.JELR01000001_gene3092 7.63e-78 235.0 COG3028@1|root,COG3028@2|Bacteria,1MZ4R@1224|Proteobacteria,1S9JJ@1236|Gammaproteobacteria,467RH@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the UPF0307 family yjgA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K09889 - - - - ko00000,ko03009 - - - DUF615 k141_10348_1 218284.CCDN010000001_gene1173 2.08e-98 325.0 COG0699@1|root,COG0699@2|Bacteria,1TR0Q@1239|Firmicutes,4HBAC@91061|Bacilli,1ZAXM@1386|Bacillus 91061|Bacilli S Dynamin family ypbR GO:0000910,GO:0003674,GO:0003824,GO:0003924,GO:0005575,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022402,GO:0022607,GO:0031224,GO:0032506,GO:0044085,GO:0044425,GO:0051301,GO:0071840,GO:0090529 - - - - - - - - - - Dynamin_N k141_13964_1 1243664.CAVL020000005_gene283 6.87e-140 404.0 COG0538@1|root,COG0538@2|Bacteria,1UHPE@1239|Firmicutes,4H9US@91061|Bacilli,1ZBWV@1386|Bacillus 91061|Bacilli C isocitrate icd - 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh k141_11511_1 1121459.AQXE01000009_gene481 3.06e-07 52.0 COG0471@1|root,COG0471@2|Bacteria,1MU0K@1224|Proteobacteria,42MR7@68525|delta/epsilon subdivisions,2WIKA@28221|Deltaproteobacteria,2M9JU@213115|Desulfovibrionales 28221|Deltaproteobacteria P PFAM Citrate transporter - - - - - - - - - - - - CitMHS,Na_sulph_symp,TrkA_C k141_11511_2 1128421.JAGA01000002_gene1198 2.67e-42 143.0 COG5485@1|root,COG5485@2|Bacteria 2|Bacteria S SnoaL-like polyketide cyclase - - - ko:K15945 ko01057,ko01130,map01057,map01130 - R09330 RC00046 ko00000,ko00001 - - - SnoaL,SnoaL_2 k141_27860_1 42565.FP66_07620 5.98e-112 324.0 COG2135@1|root,COG2135@2|Bacteria,1RER4@1224|Proteobacteria,1SBXR@1236|Gammaproteobacteria,1XMF8@135619|Oceanospirillales 135619|Oceanospirillales S Belongs to the SOS response-associated peptidase family - - - - - - - - - - - - SRAP k141_34000_2 1453501.JELR01000002_gene843 2.47e-44 160.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1NAZC@1224|Proteobacteria,1S10B@1236|Gammaproteobacteria,46CKC@72275|Alteromonadaceae 1236|Gammaproteobacteria P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec k141_29149_1 218284.CCDN010000002_gene2229 1.89e-214 616.0 COG5000@1|root,COG5002@1|root,COG5000@2|Bacteria,COG5002@2|Bacteria,1VS6X@1239|Firmicutes,4HV7W@91061|Bacilli,1ZS6R@1386|Bacillus 91061|Bacilli T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,dCache_1 k141_2974_1 103690.17132796 2.84e-27 108.0 COG1403@1|root,COG1403@2|Bacteria,1GAK5@1117|Cyanobacteria,1HTMP@1161|Nostocales 1117|Cyanobacteria V HNH endonuclease - - - - - - - - - - - - HNH_2 k141_2974_2 1116375.VEJY3_20801 4.41e-95 285.0 COG3547@1|root,COG3547@2|Bacteria,1NGR7@1224|Proteobacteria,1RMF9@1236|Gammaproteobacteria,1XURY@135623|Vibrionales 135623|Vibrionales L Transposase IS116/IS110/IS902 family - - - - - - - - - - - - DEDD_Tnp_IS110,Transposase_20 k141_35236_1 1294265.JCM21738_177 1.18e-145 419.0 COG3359@1|root,COG3359@2|Bacteria,1TQQU@1239|Firmicutes,4HDMU@91061|Bacilli,1ZAZQ@1386|Bacillus 91061|Bacilli L RNase_H superfamily yprB - - ko:K07502 - - - - ko00000 - - - RNase_H_2 k141_13965_1 1453501.JELR01000001_gene3259 5.4e-103 326.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,464R3@72275|Alteromonadaceae 1236|Gammaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K18989 - M00720 - - ko00000,ko00002,ko02000 2.A.6.2.30 - - ACR_tran k141_22050_1 1279017.AQYJ01000024_gene1099 1.48e-168 475.0 COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,1RN90@1236|Gammaproteobacteria,464N6@72275|Alteromonadaceae 1236|Gammaproteobacteria NOU Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue pilD - 3.4.23.43 ko:K02464,ko:K02654 ko03070,map03070 M00331 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko02035,ko02044 3.A.15,3.A.15.2 - - DiS_P_DiS,Peptidase_A24 k141_25788_1 1042377.AFPJ01000036_gene1134 3.58e-242 691.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MV8W@1224|Proteobacteria,1RMQA@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Outer membrane receptor proteins mostly Fe transport - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_18653_1 1042377.AFPJ01000019_gene2554 0.0 899.0 COG0362@1|root,COG0362@2|Bacteria,1MVV8@1224|Proteobacteria,1RM7P@1236|Gammaproteobacteria,465Q2@72275|Alteromonadaceae 1236|Gammaproteobacteria G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH gnd - 1.1.1.343,1.1.1.44 ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 M00004,M00006 R01528,R10221 RC00001,RC00539 ko00000,ko00001,ko00002,ko01000 - - - 6PGD,NAD_binding_2 k141_24473_1 218284.CCDN010000001_gene993 2.87e-29 110.0 COG0834@1|root,COG0834@2|Bacteria,1TT16@1239|Firmicutes,4HU0X@91061|Bacilli,1ZRKX@1386|Bacillus 91061|Bacilli ET Belongs to the bacterial solute-binding protein 3 family artP - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 k141_9075_1 1279017.AQYJ01000028_gene2077 3.78e-70 223.0 COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,1RNMZ@1236|Gammaproteobacteria,4658H@72275|Alteromonadaceae 1236|Gammaproteobacteria H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein - - 2.7.1.180 ko:K03734 - - - - ko00000,ko01000 - - - ApbE k141_9075_2 1279017.AQYJ01000028_gene2078 1.34e-124 368.0 2BWPY@1|root,2Z8BI@2|Bacteria,1QHHB@1224|Proteobacteria,1RP8D@1236|Gammaproteobacteria,4657P@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_25789_1 218284.CCDN010000001_gene439 3.98e-68 211.0 COG0500@1|root,COG2226@2|Bacteria,1V46W@1239|Firmicutes,4IPXB@91061|Bacilli 91061|Bacilli Q Mycolic acid cyclopropane synthetase - - - - - - - - - - - - Methyltransf_11 k141_23406_1 218284.CCDN010000001_gene1357 3.7e-117 355.0 COG0514@1|root,COG0514@2|Bacteria,1TPN5@1239|Firmicutes,4H9QP@91061|Bacilli,1ZC4U@1386|Bacillus 91061|Bacilli L DNA helicase recQ GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009378,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.6.4.12 ko:K03654 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind k141_11513_1 218284.CCDN010000002_gene2396 1.28e-88 275.0 COG0697@1|root,COG0697@2|Bacteria,1TP7K@1239|Firmicutes,4HAH1@91061|Bacilli,1ZBEF@1386|Bacillus 91061|Bacilli EG Spore germination protein - - - ko:K06295 - - - - ko00000 - - - GerA k141_20800_1 1294265.JCM21738_5212 4.42e-64 196.0 COG0599@1|root,COG0599@2|Bacteria,1V8W7@1239|Firmicutes,4HHDQ@91061|Bacilli,1ZGYY@1386|Bacillus 91061|Bacilli S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity yurZ - - - - - - - - - - - CMD k141_20800_2 1294265.JCM21738_5211 6.18e-164 461.0 COG1464@1|root,COG1464@2|Bacteria,1TQAS@1239|Firmicutes,4HBK0@91061|Bacilli,1ZATZ@1386|Bacillus 91061|Bacilli P Belongs to the NlpA lipoprotein family metQ - - ko:K02072,ko:K02073 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - Lipoprotein_9 k141_31412_1 223926.28809549 9.55e-208 589.0 COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,1RMWP@1236|Gammaproteobacteria,1XSX1@135623|Vibrionales 135623|Vibrionales G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate tkt - 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C,Transketolase_N k141_30235_1 1042377.AFPJ01000043_gene856 9.29e-63 209.0 COG1166@1|root,COG1166@2|Bacteria,1MU80@1224|Proteobacteria,1RP2J@1236|Gammaproteobacteria,46466@72275|Alteromonadaceae 1236|Gammaproteobacteria H arginine decarboxylase speA GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008792,GO:0009056,GO:0009058,GO:0009063,GO:0009064,GO:0009065,GO:0009308,GO:0009309,GO:0009445,GO:0009446,GO:0009987,GO:0016054,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0034641,GO:0042401,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044271,GO:0044281,GO:0044282,GO:0046395,GO:0071704,GO:0097164,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606 4.1.1.19 ko:K01585 ko00330,ko01100,map00330,map01100 M00133 R00566 RC00299 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_3590,iE2348C_1286.E2348C_3191,iEC55989_1330.EC55989_3231,iECABU_c1320.ECABU_c32250,iECED1_1282.ECED1_3401,iECIAI1_1343.ECIAI1_3071,iECIAI39_1322.ECIAI39_3358,iECO103_1326.ECO103_3518,iECO26_1355.ECO26_4037,iECOK1_1307.ECOK1_3327,iECP_1309.ECP_2933,iECS88_1305.ECS88_3221,iECSE_1348.ECSE_3207,iECSF_1327.ECSF_2737,iECSP_1301.ECSP_3909,iECUMN_1333.ECUMN_3290,iECW_1372.ECW_m3198,iECs_1301.ECs3814,iEKO11_1354.EKO11_0788,iEcE24377_1341.EcE24377A_3281,iEcHS_1320.EcHS_A3096,iEcolC_1368.EcolC_0773,iG2583_1286.G2583_3597,iLF82_1304.LF82_2157,iNRG857_1313.NRG857_14440,iPC815.YPO0929,iSBO_1134.SBO_3051,iSDY_1059.SDY_3134,iSSON_1240.SSON_3092,iSbBS512_1146.SbBS512_E3371,iWFL_1372.ECW_m3198,iZ_1308.Z4283 Orn_Arg_deC_N k141_18654_1 930169.B5T_01691 3.35e-33 119.0 COG1943@1|root,COG1943@2|Bacteria,1MZZT@1224|Proteobacteria,1S9JG@1236|Gammaproteobacteria,1XKZM@135619|Oceanospirillales 135619|Oceanospirillales L COG1943 Transposase and inactivated derivatives - - - - - - - - - - - - Y1_Tnp k141_27107_1 218284.CCDN010000007_gene3830 1.63e-102 307.0 COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,4HA31@91061|Bacilli,1ZBNF@1386|Bacillus 91061|Bacilli O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain yyxA - 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Trypsin_2 k141_12769_2 218284.CCDN010000002_gene2068 8.77e-229 639.0 COG4191@1|root,COG4191@2|Bacteria,1UZ9W@1239|Firmicutes,4HDK2@91061|Bacilli,1ZD85@1386|Bacillus 91061|Bacilli T Histidine kinase kinB3 - 2.7.13.3 ko:K07697 ko02020,map02020 M00485 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - 5TM-5TMR_LYT,HATPase_c,HisKA k141_5577_1 1042377.AFPJ01000028_gene2297 1.87e-208 600.0 COG1404@1|root,COG5640@1|root,COG1404@2|Bacteria,COG5640@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria,464PM@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG1404 Subtilisin-like serine proteases - GO:0005575,GO:0005576 - ko:K14645 ko02024,map02024 - - - ko00000,ko00001,ko01000,ko01002,ko03110 - - - PKD,PPC,P_proprotein,Peptidase_S8 k141_29150_2 935836.JAEL01000035_gene1993 1.96e-42 151.0 COG1364@1|root,COG1364@2|Bacteria,1TPBP@1239|Firmicutes,4H9TQ@91061|Bacilli,1ZAU3@1386|Bacillus 91061|Bacilli E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate argJ GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R00259,R02282 RC00004,RC00064 ko00000,ko00001,ko00002,ko01000 - - - ArgJ k141_9076_1 95619.PM1_0224425 4.22e-75 239.0 COG0451@1|root,COG0451@2|Bacteria 2|Bacteria GM ADP-glyceromanno-heptose 6-epimerase activity - - - ko:K21793 ko00333,ko01130,map00333,map01130 M00838 R11663,R11666 - ko00000,ko00001,ko00002 - - - Epimerase k141_24474_1 218284.CCDN010000001_gene1908 6.15e-136 404.0 COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1TPMS@1239|Firmicutes,4HAQD@91061|Bacilli,1ZATW@1386|Bacillus 91061|Bacilli NT COG0643 Chemotaxis protein histidine kinase and related kinases cheA - 2.7.13.3 ko:K03407 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt,P2 k141_11514_1 264732.Moth_1142 1.17e-35 136.0 COG0480@1|root,COG0480@2|Bacteria,1TPWN@1239|Firmicutes,247N4@186801|Clostridia,42FPS@68295|Thermoanaerobacterales 186801|Clostridia J TIGRFAM Translation elongation factor fusA2 - - ko:K02355 - - - - ko00000,ko03012,ko03029 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 k141_11514_2 1174504.AJTN02000250_gene2948 3.14e-05 48.5 COG1297@1|root,COG1297@2|Bacteria,1TQJP@1239|Firmicutes,4HB4S@91061|Bacilli,1ZEEQ@1386|Bacillus 91061|Bacilli S OPT oligopeptide transporter protein - - - - - - - - - - - - OPT k141_7724_2 218284.CCDN010000012_gene4441 8.11e-157 439.0 COG1428@1|root,COG1428@2|Bacteria,1TQKS@1239|Firmicutes,4HBWC@91061|Bacilli,1ZCAQ@1386|Bacillus 91061|Bacilli F Deoxyguanosine kinase dgk - 2.7.1.113 ko:K15518 ko00230,map00230 - R01967 RC00002,RC00017 ko00000,ko00001,ko01000 - - - dNK k141_25790_1 42565.FP66_14720 6.04e-168 490.0 COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,1RM9M@1236|Gammaproteobacteria,1XIDI@135619|Oceanospirillales 135619|Oceanospirillales U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA - - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW k141_818_2 1117319.PSPO_07839 3.71e-28 105.0 COG5470@1|root,COG5470@2|Bacteria,1N5NR@1224|Proteobacteria,1S96P@1236|Gammaproteobacteria,2Q3AF@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF1330) - - - - - - - - - - - - DUF1330 k141_818_3 1450525.JATV01000019_gene2390 4.78e-06 50.4 COG4538@1|root,COG4538@2|Bacteria,4PI3D@976|Bacteroidetes,1IDBC@117743|Flavobacteriia,2NXY1@237|Flavobacterium 976|Bacteroidetes S SnoaL-like domain - - - - - - - - - - - - SnoaL_2 k141_27883_1 1301098.PKB_0155 5.92e-48 164.0 COG3751@1|root,COG3751@2|Bacteria,1RJST@1224|Proteobacteria,1SN80@1236|Gammaproteobacteria 1236|Gammaproteobacteria O 2OG-Fe(II) oxygenase superfamily - - - - - - - - - - - - 2OG-FeII_Oxy_3 k141_27883_2 1509405.GV67_08275 5.08e-35 129.0 COG1216@1|root,COG1216@2|Bacteria,1MYU7@1224|Proteobacteria,2TT17@28211|Alphaproteobacteria,4BCMK@82115|Rhizobiaceae 28211|Alphaproteobacteria M Glycosyl transferase family 2 - - - - - - - - - - - - Glyco_tranf_2_2,Glyco_tranf_2_3,Glyco_trans_2_3,Glyco_transf_7C,Glycos_transf_2 k141_12788_1 218284.CCDN010000005_gene3324 8.73e-230 647.0 COG4666@1|root,COG4666@2|Bacteria,1TP0V@1239|Firmicutes,4HC4B@91061|Bacilli,1ZAWZ@1386|Bacillus 91061|Bacilli S Tripartite ATP-independent periplasmic transporter, DctM component siaT_4 - - - - - - - - - - - DUF3394,DctM k141_35272_1 1294265.JCM21738_4333 2.12e-114 351.0 COG0557@1|root,COG0557@2|Bacteria,1TQ1G@1239|Firmicutes,4HBBH@91061|Bacilli,1ZBDP@1386|Bacillus 91061|Bacilli K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs rnr - - ko:K12573 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03016,ko03019 - - - OB_RNB,RNB,S1 k141_18687_2 997296.PB1_08142 1.17e-52 170.0 COG0712@1|root,COG0712@2|Bacteria,1VAG3@1239|Firmicutes,4HKFW@91061|Bacilli,1ZG65@1386|Bacillus 91061|Bacilli C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpH - - ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - OSCP k141_35273_1 1279017.AQYJ01000023_gene3162 3.68e-71 232.0 COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,1RNKN@1236|Gammaproteobacteria,469GC@72275|Alteromonadaceae 1236|Gammaproteobacteria CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit nuoL GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015672,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0030964,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0051179,GO:0051234,GO:0055085,GO:0070469,GO:0070470,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1902600,GO:1990204 1.6.5.3 ko:K00341 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - e_coli_core.b2278,iAF1260.b2278,iBWG_1329.BWG_2052,iECDH10B_1368.ECDH10B_2440,iECDH1ME8569_1439.ECDH1ME8569_2215,iEcDH1_1363.EcDH1_1379,iJN746.PP_4129,iJO1366.b2278,iJR904.b2278,iY75_1357.Y75_RS11945 Proton_antipo_M,Proton_antipo_N k141_29181_1 1294265.JCM21738_2570 8.94e-116 332.0 COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,4H9YB@91061|Bacilli,1ZBA4@1386|Bacillus 91061|Bacilli E Belongs to the ABC transporter superfamily appF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY k141_25806_1 218284.CCDN010000001_gene21 1.55e-152 438.0 COG0541@1|root,COG0541@2|Bacteria,1TP06@1239|Firmicutes,4H9T4@91061|Bacilli,1ZB4I@1386|Bacillus 91061|Bacilli U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY ffh - 3.6.5.4 ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko01000,ko02044 3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9 - - SRP54,SRP54_N,SRP_SPB k141_25806_2 218284.CCDN010000001_gene20 7.97e-57 176.0 COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,4HKNN@91061|Bacilli,1ZGXP@1386|Bacillus 91061|Bacilli J Belongs to the bacterial ribosomal protein bS16 family rpsP GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02959 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S16 k141_25806_3 218284.CCDN010000001_gene19 4.34e-46 148.0 COG1837@1|root,COG1837@2|Bacteria,1VEG7@1239|Firmicutes,4HNX0@91061|Bacilli,1ZIW7@1386|Bacillus 91061|Bacilli S Belongs to the UPF0109 family ylqC - - ko:K06960 - - - - ko00000 - - - KH_4 k141_20824_1 586413.CCDL010000003_gene2963 1.36e-60 193.0 COG0546@1|root,COG0546@2|Bacteria,1V6BF@1239|Firmicutes,4HC3F@91061|Bacilli,23MGY@182709|Oceanobacillus 91061|Bacilli S haloacid dehalogenase-like hydrolase - - 3.2.2.9 ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 M00034,M00609 R00194,R01401 RC00063,RC00318 ko00000,ko00001,ko00002,ko01000 - - - HAD_2 k141_14003_1 1279017.AQYJ01000023_gene3093 1.21e-225 639.0 COG1228@1|root,COG1228@2|Bacteria,1MY4V@1224|Proteobacteria,1RZRK@1236|Gammaproteobacteria,46606@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Amidohydrolase family - - - - - - - - - - - - Amidohydro_1 k141_7745_1 1403313.AXBR01000033_gene5334 1.27e-152 442.0 COG0143@1|root,COG0143@2|Bacteria,1U7TS@1239|Firmicutes,4HDMP@91061|Bacilli,1ZBPT@1386|Bacillus 91061|Bacilli J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation - - 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1g k141_9104_1 319225.Plut_1952 1.89e-43 164.0 COG0013@1|root,COG0013@2|Bacteria,1FDPV@1090|Chlorobi 1090|Chlorobi J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain alaS - 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DHHA1,tRNA-synt_2c,tRNA_SAD k141_30245_1 1116375.VEJY3_02160 4e-168 475.0 COG1270@1|root,COG1270@2|Bacteria,1MURM@1224|Proteobacteria,1S6W4@1236|Gammaproteobacteria,1XSVK@135623|Vibrionales 135623|Vibrionales H COG1270 Cobalamin biosynthesis protein CobD CbiB - - 6.3.1.10 ko:K02227 ko00860,ko01100,map00860,map01100 M00122 R06529,R07302 RC00090,RC00096 ko00000,ko00001,ko00002,ko01000 - - - CobD_Cbib k141_30245_2 1280001.BAOA01000021_gene929 9.97e-154 436.0 COG0614@1|root,COG0614@2|Bacteria,1MWVF@1224|Proteobacteria,1RMV8@1236|Gammaproteobacteria,1XTID@135623|Vibrionales 135623|Vibrionales P Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC btuF - - ko:K06858 ko02010,map02010 M00241 - - ko00000,ko00001,ko00002,ko02000 3.A.1.13 - - Peripla_BP_2 k141_30245_3 1280001.BAOA01000021_gene928 1.24e-136 387.0 COG2860@1|root,COG2860@2|Bacteria,1RHQN@1224|Proteobacteria,1S5YY@1236|Gammaproteobacteria,1XV4W@135623|Vibrionales 135623|Vibrionales S membrane yadS GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - UPF0126 k141_30245_4 1116375.VEJY3_02140 3.86e-164 461.0 COG0730@1|root,COG0730@2|Bacteria,1MXNM@1224|Proteobacteria,1RRH4@1236|Gammaproteobacteria,1XSXB@135623|Vibrionales 135623|Vibrionales S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE k141_4253_1 218284.CCDN010000001_gene1279 6.53e-79 249.0 COG1233@1|root,COG1233@2|Bacteria,1UU71@1239|Firmicutes,4HA25@91061|Bacilli,1ZED4@1386|Bacillus 91061|Bacilli Q Flavin containing amine oxidoreductase - - 5.2.1.13 ko:K09835 ko00906,ko01100,ko01110,map00906,map01100,map01110 M00097 R07512 RC01960 ko00000,ko00001,ko00002,ko01000 - - - Amino_oxidase k141_4253_2 218284.CCDN010000001_gene1278 1.66e-65 213.0 COG4145@1|root,COG4145@2|Bacteria,1TQ1F@1239|Firmicutes,4HBKD@91061|Bacilli,1ZANP@1386|Bacillus 91061|Bacilli H Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family panF - - ko:K14392 - - - - ko00000,ko02000 2.A.21.1 - - SSF k141_828_4 983545.Glaag_4184 0.000225 47.0 2E4KJ@1|root,32ZFI@2|Bacteria,1ND4V@1224|Proteobacteria,1SEQG@1236|Gammaproteobacteria,468WN@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_828_5 1453501.JELR01000006_gene32 4.61e-31 122.0 COG3509@1|root,COG3509@2|Bacteria,1R66H@1224|Proteobacteria,1SZAS@1236|Gammaproteobacteria,466AM@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Esterase PHB depolymerase - - - - - - - - - - - - Esterase_phd k141_18688_1 218284.CCDN010000007_gene3946 8.91e-137 407.0 COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H9SA@91061|Bacilli,1ZBUK@1386|Bacillus 91061|Bacilli M penicillin-binding protein pbpG GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.4.1.129,3.4.16.4 ko:K21464 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase k141_14869_1 218284.CCDN010000007_gene3822 9.7e-75 235.0 COG0754@1|root,COG0754@2|Bacteria,1UTUT@1239|Firmicutes,4HBAJ@91061|Bacilli,1ZB3R@1386|Bacillus 91061|Bacilli E Glutathionylspermidine synthase preATP-grasp - - - - - - - - - - - - GSP_synth k141_25807_1 324057.Pjdr2_0976 1.13e-68 219.0 COG4213@1|root,COG4213@2|Bacteria,1TR3Q@1239|Firmicutes,4HCK3@91061|Bacilli,274YS@186822|Paenibacillaceae 91061|Bacilli G ABC transporter - - - ko:K10543 ko02010,map02010 M00215 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.4 - - Peripla_BP_4 k141_27138_2 675815.VOA_000562 9.88e-209 586.0 28N61@1|root,2ZBB3@2|Bacteria,1R95W@1224|Proteobacteria,1RYJ2@1236|Gammaproteobacteria,1XVKG@135623|Vibrionales 135623|Vibrionales S TniQ - - - - - - - - - - - - TniQ k141_27138_3 1116375.VEJY3_22941 0.0 950.0 28K8W@1|root,2Z9WM@2|Bacteria,1R4QX@1224|Proteobacteria,1S0FK@1236|Gammaproteobacteria,1XV6Q@135623|Vibrionales 135623|Vibrionales S CRISPR-associated protein (Cas_Csy2) - - - ko:K19128 - - - - ko00000,ko02048 - - - Cas_Csy2 k141_27138_4 1116375.VEJY3_22936 2.17e-203 568.0 2DB80@1|root,2Z7PG@2|Bacteria,1MWE9@1224|Proteobacteria,1RNH1@1236|Gammaproteobacteria,1XTI9@135623|Vibrionales 135623|Vibrionales S CRISPR-associated protein (Cas_Csy3) - - - ko:K19129 - - - - ko00000,ko02048 - - - Cas_Csy3 k141_27138_5 1116375.VEJY3_22931 4.39e-95 282.0 2A6VV@1|root,30VQF@2|Bacteria,1RFM5@1224|Proteobacteria,1S5U2@1236|Gammaproteobacteria,1XX5H@135623|Vibrionales 135623|Vibrionales S CRISPR-associated protein (Cas_Csy4) - - - ko:K19130 - - - - ko00000,ko01000,ko02048 - - - Cas_Csy4 k141_34024_2 203122.Sde_1703 4.86e-08 54.3 COG3507@1|root,COG3507@2|Bacteria,1QWZV@1224|Proteobacteria,1T31I@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Pectate lyase - - - - - - - - - - - - Pectate_lyase,RicinB_lectin_2 k141_36211_1 1042377.AFPJ01000009_gene331 6.94e-245 681.0 COG2211@1|root,COG2211@2|Bacteria,1MWE4@1224|Proteobacteria,1SZYW@1236|Gammaproteobacteria 1236|Gammaproteobacteria G PUCC protein - - - ko:K08226 - - - - ko00000,ko02000 2.A.1.41 - - PUCC k141_36211_2 1042377.AFPJ01000009_gene332 8.77e-263 726.0 COG2211@1|root,COG2211@2|Bacteria,1QZ99@1224|Proteobacteria,1T422@1236|Gammaproteobacteria 1236|Gammaproteobacteria G PUCC protein - - - ko:K08226 - - - - ko00000,ko02000 2.A.1.41 - - PUCC k141_22436_5 1116375.VEJY3_12540 2.14e-105 311.0 COG2207@1|root,COG2207@2|Bacteria,1N7DZ@1224|Proteobacteria,1SYZE@1236|Gammaproteobacteria,1XWDS@135623|Vibrionales 135623|Vibrionales K COG2207 AraC-type DNA-binding domain-containing proteins - - - - - - - - - - - - HTH_18 k141_3239_2 1043493.BBLU01000014_gene1312 4.52e-46 158.0 COG1131@1|root,COG1131@2|Bacteria,2GKEH@201174|Actinobacteria 201174|Actinobacteria V ABC transporter - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 k141_23775_1 1519464.HY22_13490 0.000407 41.6 COG0698@1|root,COG0698@2|Bacteria 2|Bacteria G galactose-6-phosphate isomerase activity rpiB - 5.3.1.6 ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01056,R09030 RC00376,RC00434 ko00000,ko00001,ko00002,ko01000 - - - LacAB_rpiB k141_12962_2 218284.CCDN010000009_gene4320 3.22e-62 201.0 COG0477@1|root,COG2814@2|Bacteria,1TS3C@1239|Firmicutes,4HC3B@91061|Bacilli,1ZS79@1386|Bacillus 91061|Bacilli EGP Nucleoside H+ symporter ywbF - - ko:K05820 - - - - ko00000,ko02000 2.A.1.27 - - MFS_1_like k141_32940_1 1116375.VEJY3_20141 2.61e-190 531.0 COG0765@1|root,COG0765@2|Bacteria,1R4RU@1224|Proteobacteria,1SKVH@1236|Gammaproteobacteria,1XT8A@135623|Vibrionales 135623|Vibrionales P COG0765 ABC-type amino acid transport system, permease component - - - ko:K02029 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 k141_32940_2 223926.28809052 1.04e-30 114.0 COG2501@1|root,COG2501@2|Bacteria,1N8C4@1224|Proteobacteria,1SCIR@1236|Gammaproteobacteria,1XY0I@135623|Vibrionales 135623|Vibrionales S S4 domain - - - ko:K14761 - - - - ko00000,ko03009 - - - S4_2 k141_17420_1 1294265.JCM21738_2122 2.25e-72 235.0 COG1368@1|root,COG1368@2|Bacteria,1TRMA@1239|Firmicutes,4H9S0@91061|Bacilli,1ZBBV@1386|Bacillus 91061|Bacilli M Belongs to the LTA synthase family yqgS - 2.7.8.20 ko:K01138,ko:K19005 ko00561,ko01100,map00561,map01100 - R05081,R10849 RC00017 ko00000,ko00001,ko01000 - - - Sulfatase k141_20015_1 232721.Ajs_3582 3.25e-25 109.0 COG3540@1|root,COG3540@2|Bacteria,1MWAF@1224|Proteobacteria,2VKX4@28216|Betaproteobacteria,4ABTZ@80864|Comamonadaceae 28216|Betaproteobacteria P Alkaline phosphatase - - 3.1.3.1 ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 M00126 R04620 RC00017 ko00000,ko00001,ko00002,ko01000 - - - PhoD,PhoD_N k141_11812_1 218284.CCDN010000002_gene2858 4.85e-84 268.0 COG1657@1|root,COG1657@2|Bacteria,1TRRG@1239|Firmicutes,4HA2Q@91061|Bacilli,1ZBBW@1386|Bacillus 91061|Bacilli I COG1657 Squalene cyclase sqhC - 4.2.1.137 ko:K18115 - - - - ko00000,ko01000 - - - SQHop_cyclase_C,SQHop_cyclase_N k141_5778_1 1444306.JFZC01000059_gene890 1.16e-70 250.0 COG5280@1|root,COG5412@1|root,COG5280@2|Bacteria,COG5412@2|Bacteria,1TQ28@1239|Firmicutes,4HGP4@91061|Bacilli,26PXR@186821|Sporolactobacillaceae 91061|Bacilli S minor tail protein - - - - - - - - - - - - PhageMin_Tail k141_22437_1 1078085.HMPREF1210_03096 8.61e-60 213.0 COG1404@1|root,COG1404@2|Bacteria,1TPH1@1239|Firmicutes,4HBQH@91061|Bacilli,26DQR@186818|Planococcaceae 91061|Bacilli M Belongs to the peptidase S8 family - - - - - - - - - - - - Inhibitor_I9,PA,Peptidase_S8,SLH,fn3_5 k141_28046_1 1116375.VEJY3_05710 0.0 1011.0 COG4166@1|root,COG4166@2|Bacteria,1P91R@1224|Proteobacteria,1T1RS@1236|Gammaproteobacteria,1XUUH@135623|Vibrionales 135623|Vibrionales E COG4166 ABC-type oligopeptide transport system, periplasmic component sapA - - ko:K19226 ko01503,ko02010,map01503,map02010 M00739 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.5 - - SBP_bac_5 k141_28046_2 1219076.N646_0218 5.33e-150 427.0 COG4168@1|root,COG4168@2|Bacteria,1QUAU@1224|Proteobacteria,1T1RR@1236|Gammaproteobacteria,1XTN1@135623|Vibrionales 135623|Vibrionales P peptide transport system, permease sapB - - ko:K19227 ko01503,ko02010,map01503,map02010 M00739 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.5 - - BPD_transp_1 k141_30401_1 218284.CCDN010000001_gene508 4.73e-238 686.0 COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,4H9T3@91061|Bacilli,1ZCIC@1386|Bacillus 91061|Bacilli L DNA polymerase dnaE - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon k141_35514_1 218284.CCDN010000001_gene756 1.16e-169 482.0 COG0423@1|root,COG0423@2|Bacteria,1TP94@1239|Firmicutes,4HB9A@91061|Bacilli,1ZCAP@1386|Bacillus 91061|Bacilli J Catalyzes the attachment of glycine to tRNA(Gly) glyQS GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.14 ko:K01880 ko00970,map00970 M00359,M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - iSB619.SA_RS07880 HGTP_anticodon,tRNA-synt_2b k141_5779_1 935837.JAEK01000038_gene2892 9.3e-16 71.2 29S0U@1|root,30D56@2|Bacteria,1UAV6@1239|Firmicutes,4IM80@91061|Bacilli,1ZJFT@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_5779_2 218284.CCDN010000002_gene2073 1.67e-46 150.0 2E5FN@1|root,3307C@2|Bacteria,1VH91@1239|Firmicutes,4HP9B@91061|Bacilli,1ZJ6Z@1386|Bacillus 91061|Bacilli S Belongs to the UPF0180 family ykuS - - - - - - - - - - - UPF0180 k141_7048_2 1453501.JELR01000005_gene1645 4.51e-62 195.0 COG1451@1|root,COG1451@2|Bacteria,1MXZU@1224|Proteobacteria,1S9E4@1236|Gammaproteobacteria,467T2@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function DUF45 - - - ko:K07043 - - - - ko00000 - - - DUF45 k141_23777_1 218284.CCDN010000001_gene1801 2.45e-83 254.0 COG0464@1|root,COG0464@2|Bacteria,1TPQZ@1239|Firmicutes,4HCQK@91061|Bacilli,1ZBII@1386|Bacillus 91061|Bacilli O stage V sporulation protein K spoVK - - ko:K06413 - - - - ko00000 - - - AAA k141_26062_1 1128398.Curi_c16640 3.82e-23 102.0 COG3383@1|root,COG3383@2|Bacteria,1UI1F@1239|Firmicutes,25EAG@186801|Clostridia,26CSW@186813|unclassified Clostridiales 186801|Clostridia C Molybdopterin oxidoreductase Fe4S4 domain nuoG - 1.17.1.10,1.17.1.11,1.6.5.3 ko:K00336,ko:K05299,ko:K22341 ko00190,ko00680,ko00720,ko01100,ko01120,ko01200,map00190,map00680,map00720,map01100,map01120,map01200 M00144,M00377 R00134,R11945 RC00061,RC02796 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Fer2_4,Fer4,Fer4_6,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3 k141_17434_6 223926.28806177 0.0 1072.0 COG0369@1|root,COG1151@2|Bacteria,1N88B@1224|Proteobacteria,1RP1I@1236|Gammaproteobacteria,1XSED@135623|Vibrionales 135623|Vibrionales C Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O hcp - 1.7.99.1 ko:K05601 ko00910,map00910 - R00143 RC02797 ko00000,ko00001,ko01000 - - - Prismane k141_17434_7 223926.28806178 0.0 946.0 COG3604@1|root,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,1T1G7@1236|Gammaproteobacteria,1XSRB@135623|Vibrionales 135623|Vibrionales K COG3604 Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains - - - ko:K12266 ko05132,map05132 - - - ko00000,ko00001,ko03000 - - - GAF,HTH_8,Sigma54_activat k141_17434_8 1116375.VEJY3_05795 5.37e-78 235.0 COG3133@1|root,COG3133@2|Bacteria,1RA1D@1224|Proteobacteria,1S202@1236|Gammaproteobacteria,1XX9Q@135623|Vibrionales 135623|Vibrionales M Outer membrane lipoprotein - - - ko:K06077 - - - - ko00000 - - - Rick_17kDa_Anti k141_17434_9 1116375.VEJY3_05800 6.13e-131 373.0 COG0558@1|root,COG0558@2|Bacteria,1RD5Y@1224|Proteobacteria,1S2R8@1236|Gammaproteobacteria,1XTFE@135623|Vibrionales 135623|Vibrionales I Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - 2.7.8.5 ko:K00995 ko00564,ko01100,map00564,map01100 - R01801 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 - - - CDP-OH_P_transf k141_17434_10 1116375.VEJY3_05805 3.9e-133 379.0 COG4136@1|root,COG4136@2|Bacteria,1RA88@1224|Proteobacteria,1S4G8@1236|Gammaproteobacteria,1XVW5@135623|Vibrionales 135623|Vibrionales S ABC transporter, ATP-binding protein - - - ko:K05779 - M00192 - - ko00000,ko00002,ko02000 - - - ABC_tran k141_17434_11 1116375.VEJY3_05810 9.85e-123 365.0 COG4135@1|root,COG4135@2|Bacteria,1MV6R@1224|Proteobacteria,1RR4B@1236|Gammaproteobacteria,1XSNA@135623|Vibrionales 135623|Vibrionales P transport system, permease component - - - ko:K05778 - M00192 - - ko00000,ko00002,ko02000 - - - BPD_transp_1 k141_24764_1 935836.JAEL01000014_gene2076 2.8e-38 135.0 COG2972@1|root,COG2972@2|Bacteria,1V4EZ@1239|Firmicutes,4HH4N@91061|Bacilli,1ZCDD@1386|Bacillus 91061|Bacilli T Histidine kinase - - - - - - - - - - - - His_kinase k141_21009_2 1279017.AQYJ01000027_gene1935 9.68e-17 80.9 COG5607@1|root,COG5607@2|Bacteria,1RH6R@1224|Proteobacteria,1S7KA@1236|Gammaproteobacteria 1236|Gammaproteobacteria S CHAD domain - - - - - - - - - - - - CHAD k141_9447_1 1279017.AQYJ01000021_gene2819 3.75e-189 537.0 COG3004@1|root,COG3004@2|Bacteria,1MW15@1224|Proteobacteria,1RNDE@1236|Gammaproteobacteria,464UV@72275|Alteromonadaceae 1236|Gammaproteobacteria P ) H( ) antiporter that extrudes sodium in exchange for external protons nhaA - - ko:K03313 - - - - ko00000,ko02000 2.A.33.1 - - Na_H_antiport_1,Thioredoxin_4 k141_9447_2 713586.KB900536_gene2107 2.68e-28 110.0 COG1656@1|root,COG1656@2|Bacteria,1R442@1224|Proteobacteria,1S4UH@1236|Gammaproteobacteria 1236|Gammaproteobacteria H Mut7-C RNAse domain - - - ko:K09122 - - - - ko00000 - - - Mut7-C,Ub-Mut7C k141_16383_2 1453501.JELR01000001_gene3239 4.22e-62 194.0 2EDVS@1|root,337QX@2|Bacteria,1NEZW@1224|Proteobacteria,1SCKV@1236|Gammaproteobacteria,46C7E@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_22467_2 1238450.VIBNISOn1_1670020 1.35e-256 709.0 COG4580@1|root,COG4580@2|Bacteria,1MX77@1224|Proteobacteria,1RPMF@1236|Gammaproteobacteria,1XU0M@135623|Vibrionales 135623|Vibrionales M Involved in the transport of maltose and maltodextrins lamB GO:0003674,GO:0005215,GO:0005363,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015154,GO:0015157,GO:0015267,GO:0015288,GO:0015481,GO:0015766,GO:0015768,GO:0015772,GO:0022803,GO:0022829,GO:0022857,GO:0034219,GO:0051179,GO:0051234,GO:0055085,GO:0071702 - ko:K02024 - - - - ko00000,ko02000 1.B.3.1.1 - - LamB k141_37651_1 218284.CCDN010000005_gene3422 1.3e-131 377.0 COG1655@1|root,COG1655@2|Bacteria,1UY0V@1239|Firmicutes,4HDH4@91061|Bacilli,1ZD58@1386|Bacillus 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2225) - - - ko:K09766 - - - - ko00000 - - - DUF2225 k141_34249_1 218284.CCDN010000004_gene3044 5.6e-149 431.0 COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,4HACR@91061|Bacilli,1ZCC3@1386|Bacillus 91061|Bacilli M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein murF - 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 - R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M k141_34249_2 218284.CCDN010000004_gene3045 3.05e-82 252.0 COG1181@1|root,COG1181@2|Bacteria,1TP2Y@1239|Firmicutes,4H9KB@91061|Bacilli,1ZDA3@1386|Bacillus 91061|Bacilli F Belongs to the D-alanine--D-alanine ligase family ddl - 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Dala_Dala_lig_C,Dala_Dala_lig_N k141_3257_1 1280001.BAOA01000008_gene4089 6.55e-170 481.0 COG3016@1|root,COG3016@2|Bacteria,1MX1I@1224|Proteobacteria,1RPWZ@1236|Gammaproteobacteria,1XT3W@135623|Vibrionales 135623|Vibrionales S Haem-binding uptake, Tiki superfamily, ChaN - - - - - - - - - - - - Cofac_haem_bdg k141_3257_2 1116375.VEJY3_11165 1.21e-179 502.0 COG0500@1|root,COG2226@2|Bacteria,1MXDY@1224|Proteobacteria,1RMU7@1236|Gammaproteobacteria,1XTTF@135623|Vibrionales 135623|Vibrionales H COG0500 SAM-dependent methyltransferases rrmA - 2.1.1.187 ko:K00563 - - R07233 RC00003 ko00000,ko01000,ko03009 - - - Methyltransf_25,Methyltransf_31 k141_29459_1 240016.ABIZ01000001_gene4776 5.78e-89 277.0 COG1005@1|root,COG1005@2|Bacteria,46SIJ@74201|Verrucomicrobia,2ITZ1@203494|Verrucomicrobiae 203494|Verrucomicrobiae C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone nuoH - 1.6.5.3 ko:K00337 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - NADHdh k141_28071_1 1042377.AFPJ01000019_gene2538 3.42e-225 632.0 COG4242@1|root,COG4242@2|Bacteria,1R5TW@1224|Proteobacteria,1RYMR@1236|Gammaproteobacteria 1236|Gammaproteobacteria PQ Belongs to the peptidase S51 family - - - - - - - - - - - - PPC,Peptidase_S51 k141_28071_2 1453501.JELR01000001_gene2025 1.55e-46 151.0 2C9TE@1|root,32RPW@2|Bacteria,1N8DZ@1224|Proteobacteria,1SF18@1236|Gammaproteobacteria,46BPG@72275|Alteromonadaceae 1236|Gammaproteobacteria - - VL23_07270 - - - - - - - - - - - - k141_20047_1 218284.CCDN010000005_gene3281 1.3e-193 540.0 COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,4HA2S@91061|Bacilli,1ZAUS@1386|Bacillus 91061|Bacilli P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components oppB - - ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - BPD_transp_1 k141_20047_2 218284.CCDN010000005_gene3280 4.4e-207 585.0 COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,4HAMK@91061|Bacilli,1ZBB4@1386|Bacillus 91061|Bacilli E ABC transporter substrate-binding protein oppA - - ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 k141_35541_1 1089550.ATTH01000001_gene2443 1.31e-144 422.0 COG0372@1|root,COG0372@2|Bacteria,4NFXK@976|Bacteroidetes,1FIQ8@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes C Belongs to the citrate synthase family prpC - 2.3.3.1,2.3.3.5 ko:K01647,ko:K01659 ko00020,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351,R00931 RC00004,RC00067,RC00406,RC02827 br01601,ko00000,ko00001,ko00002,ko01000 - - - Citrate_synt k141_1998_1 218284.CCDN010000002_gene2951 2.25e-95 287.0 COG0111@1|root,COG0111@2|Bacteria,1TSDK@1239|Firmicutes,4HAW5@91061|Bacilli,1ZCEY@1386|Bacillus 91061|Bacilli EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family ghrA - - - - - - - - - - - 2-Hacid_dh,2-Hacid_dh_C k141_7087_1 218284.CCDN010000005_gene3197 9.49e-124 379.0 COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,4H9T9@91061|Bacilli,1ZBH0@1386|Bacillus 91061|Bacilli S YhgE Pip N-terminal domain protein yhgE - - ko:K01421 - - - - ko00000 - - - ABC2_membrane_3,DUF3533 k141_5816_1 1279017.AQYJ01000025_gene702 1.59e-63 218.0 COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,1RPC6@1236|Gammaproteobacteria,46518@72275|Alteromonadaceae 1236|Gammaproteobacteria L UvrD-like helicase C-terminal domain addA - - - - - - - - - - - PDDEXK_1,UvrD-helicase,UvrD_C k141_32983_1 1211817.CCAT010000085_gene1901 7.01e-39 141.0 COG0667@1|root,COG0667@2|Bacteria,1V53W@1239|Firmicutes,24KNB@186801|Clostridia 186801|Clostridia C Aldo/keto reductase family - - - - - - - - - - - - Aldo_ket_red k141_4444_1 1453501.JELR01000002_gene325 4.34e-57 197.0 COG1629@1|root,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria,4651V@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_37652_1 218284.CCDN010000001_gene679 4.85e-41 145.0 arCOG13259@1|root,2ZCJ1@2|Bacteria,1V55Y@1239|Firmicutes,4IS41@91061|Bacilli,1ZS10@1386|Bacillus 91061|Bacilli E Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links tgl - 2.3.2.13 ko:K00686 - - - - ko00000,ko01000 - - - - k141_9449_1 1453501.JELR01000002_gene382 1.55e-10 61.2 COG0725@1|root,COG0725@2|Bacteria,1MVNA@1224|Proteobacteria,1RN71@1236|Gammaproteobacteria 1236|Gammaproteobacteria P ABC transporter, periplasmic molybdate-binding protein modA - - ko:K02020 ko02010,map02010 M00189 - - ko00000,ko00001,ko00002,ko02000 3.A.1.8 - - SBP_bac_11 k141_11836_1 1116375.VEJY3_04300 0.0 1131.0 COG0204@1|root,COG0204@2|Bacteria,1MWDY@1224|Proteobacteria,1RRXF@1236|Gammaproteobacteria,1XT85@135623|Vibrionales 135623|Vibrionales I COG0477 Permeases of the major facilitator superfamily - - - - - - - - - - - - Acyltransferase,MFS_1 k141_11836_2 674977.VMC_11050 3.86e-126 360.0 COG1309@1|root,COG1309@2|Bacteria,1N0XU@1224|Proteobacteria,1S91U@1236|Gammaproteobacteria,1XVJX@135623|Vibrionales 135623|Vibrionales K Transcriptional regulator - - - - - - - - - - - - WHG k141_11836_3 1116375.VEJY3_04310 1.9e-182 510.0 COG4395@1|root,COG4395@2|Bacteria,1NSUG@1224|Proteobacteria,1RZ3S@1236|Gammaproteobacteria,1XTTA@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria - - - - - - - - - - - - DUF1517,Tim44 k141_11836_4 223926.28805927 2.34e-200 561.0 COG0845@1|root,COG0845@2|Bacteria,1R8W0@1224|Proteobacteria,1S0GT@1236|Gammaproteobacteria,1XSIB@135623|Vibrionales 135623|Vibrionales M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - - - - - - - - - - HlyD_D23 k141_11836_5 1116375.VEJY3_04320 0.0 1842.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1XSBB@135623|Vibrionales 135623|Vibrionales V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K03296,ko:K18138 ko01501,ko01503,map01501,map01503 M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2 - - ACR_tran k141_11836_6 1116375.VEJY3_04325 3.09e-70 211.0 COG3492@1|root,COG3492@2|Bacteria,1MZ3I@1224|Proteobacteria,1S8SI@1236|Gammaproteobacteria,1XXCE@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria - - - ko:K09948 - - - - ko00000 - - - DUF1244 k141_22469_1 1116375.VEJY3_05690 1.08e-102 301.0 COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,1RMEI@1236|Gammaproteobacteria,1XTTI@135623|Vibrionales 135623|Vibrionales P ABC-type antimicrobial peptide transport system, ATPase component sapF - - ko:K19230 ko01503,ko02010,map01503,map02010 M00739 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.5 - - ABC_tran k141_29461_1 633149.Bresu_2498 2.47e-17 86.7 COG2234@1|root,COG2234@2|Bacteria,1MWQ0@1224|Proteobacteria,2U1HX@28211|Alphaproteobacteria,2KICA@204458|Caulobacterales 204458|Caulobacterales S Peptidase family M28 - - - - - - - - - - - - Peptidase_M28 k141_1999_1 218284.CCDN010000001_gene804 1.99e-38 128.0 COG4483@1|root,COG4483@2|Bacteria,1VK83@1239|Firmicutes,4HRG2@91061|Bacilli,1ZISV@1386|Bacillus 91061|Bacilli S protein conserved in bacteria yqgQ - - - - - - - - - - - DUF910 k141_34251_1 187272.Mlg_1964 1.78e-81 263.0 COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,1RMUH@1236|Gammaproteobacteria,1WWAH@135613|Chromatiales 135613|Chromatiales C TIGRFAM NADH-quinone oxidoreductase, chain G - - 1.6.5.3 ko:K00336 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Fer2_4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3 k141_17438_1 314230.DSM3645_10432 3.66e-52 180.0 COG0166@1|root,COG0166@2|Bacteria,2IXRA@203682|Planctomycetes 203682|Planctomycetes G Belongs to the GPI family pgi - 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGI k141_17438_2 886293.Sinac_6551 1.05e-71 240.0 COG1048@1|root,COG1048@2|Bacteria,2IY29@203682|Planctomycetes 203682|Planctomycetes C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate - - 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_C k141_26076_1 1453501.JELR01000005_gene1595 8.75e-286 799.0 COG0366@1|root,COG0366@2|Bacteria,1MU90@1224|Proteobacteria,1RQ1S@1236|Gammaproteobacteria,464Q7@72275|Alteromonadaceae 1236|Gammaproteobacteria G Belongs to the glycosyl hydrolase 13 family - - 3.2.1.135 ko:K21575 - - - - ko00000,ko01000 - GH13 - Alpha-amylase,Cyc-maltodext_C,Cyc-maltodext_N k141_20048_2 1453501.JELR01000005_gene1577 1.29e-117 367.0 COG1629@1|root,COG1629@2|Bacteria,1MV8W@1224|Proteobacteria,1RQEQ@1236|Gammaproteobacteria,46A77@72275|Alteromonadaceae 1236|Gammaproteobacteria P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec k141_22471_1 768066.HELO_3446 1.22e-40 149.0 COG0404@1|root,COG0446@1|root,COG0404@2|Bacteria,COG0446@2|Bacteria,1MVEK@1224|Proteobacteria,1RQKR@1236|Gammaproteobacteria,1XIC3@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the GcvT family - - 1.5.3.1 ko:K00302 ko00260,ko01100,map00260,map01100 - R00610 RC00060,RC00557 ko00000,ko00001,ko01000 - - - FAD_oxidored,Fer2_4,GCV_T,GCV_T_C,Pyr_redox_2 k141_22471_2 768066.HELO_3447 1.23e-48 157.0 COG4311@1|root,COG4311@2|Bacteria,1MZC3@1224|Proteobacteria,1S6M7@1236|Gammaproteobacteria,1XK1T@135619|Oceanospirillales 135619|Oceanospirillales E Sarcosine oxidase, delta subunit - - 1.5.3.1 ko:K00304 ko00260,ko01100,map00260,map01100 - R00610 RC00060,RC00557 ko00000,ko00001,ko01000 - - - SoxD k141_37654_1 1453501.JELR01000002_gene1069 2.08e-40 139.0 COG1999@1|root,COG1999@2|Bacteria,1N6R6@1224|Proteobacteria,1SC88@1236|Gammaproteobacteria,46868@72275|Alteromonadaceae 1236|Gammaproteobacteria S signal sequence binding - - - - - - - - - - - - - k141_37654_2 930166.CD58_00495 4e-15 74.7 COG1612@1|root,COG1612@2|Bacteria,1MVJ4@1224|Proteobacteria,1RQWB@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Cytochrome oxidase assembly ctaA - - ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 M00154 R07412 RC00769 ko00000,ko00001,ko00002,ko03029 3.D.4.4 - - COX15-CtaA k141_7089_1 218284.CCDN010000002_gene2038 3.23e-145 437.0 COG0457@1|root,COG0457@2|Bacteria,1UATF@1239|Firmicutes,4HE1D@91061|Bacilli,1ZBPM@1386|Bacillus 91061|Bacilli S ATPase. Has a role at an early stage in the morphogenesis of the spore coat - - - - - - - - - - - - Dynamin_N,TPR_8 k141_16387_1 1294265.JCM21738_3794 1.23e-73 233.0 COG2252@1|root,COG2252@2|Bacteria,1TQC6@1239|Firmicutes,4HANG@91061|Bacilli,1ZARH@1386|Bacillus 91061|Bacilli S permease pbuG - - ko:K06901 - - - - ko00000,ko02000 2.A.1.40 - iYO844.BSU06370 Xan_ur_permease k141_16387_2 1294265.JCM21738_3793 9.13e-21 88.2 COG3711@1|root,COG3711@2|Bacteria,1TQJJ@1239|Firmicutes,4HBB3@91061|Bacilli,1ZBDU@1386|Bacillus 91061|Bacilli K antiterminator glcT - - ko:K03480,ko:K03488 - - - - ko00000,ko03000 - - - CAT_RBD,PRD k141_34252_1 1453501.JELR01000002_gene578 1.3e-155 443.0 COG3111@1|root,COG3111@2|Bacteria,1MU8B@1224|Proteobacteria,1S1UJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S short chain amide porin - - - - - - - - - - - - - k141_24767_1 1033734.CAET01000038_gene91 1.2e-56 180.0 COG0346@1|root,COG0346@2|Bacteria,1V7AX@1239|Firmicutes,4HJ5Z@91061|Bacilli,1ZFXR@1386|Bacillus 91061|Bacilli E lactoylglutathione lyase activity - - - - - - - - - - - - Glyoxalase k141_29463_1 203122.Sde_3447 8.5e-100 321.0 COG4677@1|root,COG4677@2|Bacteria,1QX0R@1224|Proteobacteria,1T32P@1236|Gammaproteobacteria,46D3U@72275|Alteromonadaceae 1236|Gammaproteobacteria G Pectinesterase - - - - - - - - - - - - Pectinesterase k141_5817_1 218284.CCDN010000001_gene1102 2.42e-73 229.0 COG0240@1|root,COG0240@2|Bacteria,1TQ5P@1239|Firmicutes,4HAXW@91061|Bacilli,1ZCHQ@1386|Bacillus 91061|Bacilli I Glycerol-3-phosphate dehydrogenase gpsA GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0047952,GO:0055114 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 - R00842,R00844 RC00029 ko00000,ko00001,ko01000 - - - NAD_Gly3P_dh_C,NAD_Gly3P_dh_N k141_21013_2 1250232.JQNJ01000001_gene747 2.82e-38 129.0 COG2963@1|root,COG2963@2|Bacteria,4NT06@976|Bacteroidetes,1I4MW@117743|Flavobacteriia 976|Bacteroidetes L Helix-turn-helix domain - - - - - - - - - - - - HTH_Tnp_1 k141_26077_1 1415756.JQMY01000001_gene3641 1.24e-19 92.4 COG1215@1|root,COG1215@2|Bacteria,1RIJ7@1224|Proteobacteria,2TXDT@28211|Alphaproteobacteria,2PEWV@252301|Oceanicola 28211|Alphaproteobacteria M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 k141_17440_1 398511.BpOF4_16250 1.33e-98 290.0 COG0110@1|root,COG0110@2|Bacteria,1TQEX@1239|Firmicutes,4HAJ0@91061|Bacilli,1ZDPK@1386|Bacillus 91061|Bacilli S COG0110 Acetyltransferase (isoleucine patch superfamily) maa - 2.3.1.79 ko:K00661 - - - - ko00000,ko01000 - - - CM_2,Hexapep,Hexapep_2,Mac k141_35546_1 1117379.BABA_12236 3.83e-10 63.2 29ZUE@1|root,30MVI@2|Bacteria,1U101@1239|Firmicutes,4IAG5@91061|Bacilli,1ZG34@1386|Bacillus 91061|Bacilli S Spore coat protein CotO - - - - - - - - - - - - Spore_coat_CotO k141_20049_1 218284.CCDN010000002_gene2162 8.98e-170 483.0 COG5520@1|root,COG5520@2|Bacteria,1TS99@1239|Firmicutes,4HEUA@91061|Bacilli,1ZF3X@1386|Bacillus 91061|Bacilli M Belongs to the glycosyl hydrolase 30 family - - 3.2.1.45 ko:K01201 ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142 - R01498 RC00059,RC00451 ko00000,ko00001,ko01000 - GH30 - Glyco_hydro_30,Glyco_hydro_30C k141_7091_1 1294265.JCM21738_1659 3.86e-93 272.0 COG1051@1|root,COG1051@2|Bacteria,1V3BX@1239|Firmicutes,4HGE6@91061|Bacilli,1ZFT4@1386|Bacillus 91061|Bacilli F Nudix hydrolase yvcI - 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - - NUDIX k141_4445_1 1042377.AFPJ01000024_gene703 1.94e-18 80.9 COG1320@1|root,COG1320@2|Bacteria,1QTGI@1224|Proteobacteria,1RTH6@1236|Gammaproteobacteria,468PE@72275|Alteromonadaceae 1236|Gammaproteobacteria P Na+/H+ antiporter subunit - - - ko:K05571 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - PhaG_MnhG_YufB k141_34266_1 218284.CCDN010000004_gene3156 7.65e-114 332.0 COG0561@1|root,COG0561@2|Bacteria,1V2XI@1239|Firmicutes,4HG2U@91061|Bacilli,1ZB1F@1386|Bacillus 91061|Bacilli S hydrolases of the HAD superfamily yhaX - - - - - - - - - - - Hydrolase_3 k141_9472_2 1220534.B655_0762 0.000293 42.4 COG0451@1|root,arCOG01369@2157|Archaea,2XTTP@28890|Euryarchaeota,23NT5@183925|Methanobacteria 28890|Euryarchaeota M PFAM NAD dependent epimerase dehydratase family - - 5.1.3.6 ko:K08679 ko00520,ko01100,map00520,map01100 - R01385 RC00289 ko00000,ko00001,ko01000 - - - Epimerase k141_12058_1 218284.CCDN010000001_gene97 4.04e-103 312.0 COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,4HBK9@91061|Bacilli,1ZBHM@1386|Bacillus 91061|Bacilli I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) yngE - - - - - - - - - - iYO844.BSU18210 Carboxyl_trans k141_33431_1 218284.CCDN010000001_gene948 1.28e-25 99.0 2BYG1@1|root,33M6N@2|Bacteria,1U3TH@1239|Firmicutes,4IC1U@91061|Bacilli,1ZIYH@1386|Bacillus 91061|Bacilli - - yqhP - - - - - - - - - - - - k141_26373_1 1453501.JELR01000002_gene1316 2.08e-90 276.0 COG4313@1|root,COG4313@2|Bacteria,1MXNW@1224|Proteobacteria,1S14R@1236|Gammaproteobacteria,4680H@72275|Alteromonadaceae 1236|Gammaproteobacteria C Protein involved in meta-pathway of phenol degradation - - - - - - - - - - - - DUF3570,Phenol_MetA_deg k141_9663_1 1279017.AQYJ01000027_gene1667 2.54e-52 177.0 COG2223@1|root,COG2223@2|Bacteria,1MU27@1224|Proteobacteria,1RMUK@1236|Gammaproteobacteria,4652C@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG2223 Nitrate nitrite transporter narK1 - - ko:K02575 ko00910,map00910 M00615 - - ko00000,ko00001,ko00002,ko02000 2.A.1.8 - - MFS_1 k141_25108_1 218284.CCDN010000001_gene745 2.05e-89 264.0 29RH9@1|root,30CK6@2|Bacteria,1UA17@1239|Firmicutes,4IK9T@91061|Bacilli,1ZG2T@1386|Bacillus 91061|Bacilli - - yqfB - - - - - - - - - - - - k141_25108_2 218284.CCDN010000001_gene744 1.35e-21 92.0 COG4864@1|root,COG4864@2|Bacteria,1TPTD@1239|Firmicutes,4HAIX@91061|Bacilli,1ZD1V@1386|Bacillus 91061|Bacilli S UPF0365 protein yqfA - - - - - - - - - - - YdfA_immunity k141_21613_1 1116375.VEJY3_21406 4.39e-245 676.0 COG1168@1|root,COG1168@2|Bacteria,1MY33@1224|Proteobacteria,1RP58@1236|Gammaproteobacteria,1XUW6@135623|Vibrionales 135623|Vibrionales E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities - - 4.4.1.8 ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 - R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 k141_21613_2 1116375.VEJY3_21411 2.04e-129 377.0 COG5434@1|root,COG5434@2|Bacteria,1MXFR@1224|Proteobacteria,1RSER@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Protein of unknown function (DUF3737) - - - - - - - - - - - - DUF3737 k141_36989_2 265729.GS18_0216345 9.66e-32 120.0 COG1664@1|root,COG1664@2|Bacteria,1V6E6@1239|Firmicutes,4HK3W@91061|Bacilli,1ZFY4@1386|Bacillus 91061|Bacilli M COG1664 Integral membrane protein CcmA involved in cell shape determination - - - - - - - - - - - - Bactofilin k141_12059_1 926569.ANT_16100 7.33e-85 265.0 COG1418@1|root,COG4372@1|root,COG1418@2|Bacteria,COG4372@2|Bacteria,2G620@200795|Chloroflexi 200795|Chloroflexi S Endoribonuclease that initiates mRNA decay rny - - ko:K18682 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - DUF3552,HD,KH_1 k141_4916_1 1116472.MGMO_60c00200 1.61e-47 171.0 COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,1RMMD@1236|Gammaproteobacteria,1XE58@135618|Methylococcales 135618|Methylococcales H Catalyzes the oxidation of L-aspartate to iminoaspartate nadB - 1.4.3.16 ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 M00115 R00357,R00481 RC00006,RC02566 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C k141_14462_2 1279017.AQYJ01000027_gene1616 5.12e-118 340.0 COG0762@1|root,COG0762@2|Bacteria,1RCZV@1224|Proteobacteria,1S6DW@1236|Gammaproteobacteria,467FD@72275|Alteromonadaceae 1236|Gammaproteobacteria S integral membrane protein yggT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02221 - - - - ko00000,ko02044 - - - YGGT k141_35798_1 218284.CCDN010000001_gene611 1.01e-238 667.0 COG2199@1|root,COG3706@2|Bacteria,1TQIK@1239|Firmicutes,4HEDD@91061|Bacilli,1ZB59@1386|Bacillus 91061|Bacilli T COG2199 FOG GGDEF domain - - - - - - - - - - - - GAF,GAF_2,GGDEF k141_33433_1 42565.FP66_07615 1.92e-64 200.0 COG1309@1|root,COG1309@2|Bacteria,1N0XU@1224|Proteobacteria,1S91U@1236|Gammaproteobacteria,1XPWB@135619|Oceanospirillales 135619|Oceanospirillales K transcriptional regulator - - - - - - - - - - - - TetR_N,WHG k141_26374_1 218284.CCDN010000001_gene1627 4.04e-128 370.0 COG1597@1|root,COG1597@2|Bacteria,1TQ9A@1239|Firmicutes,4HCPU@91061|Bacilli,1ZECD@1386|Bacillus 91061|Bacilli I Diacylglycerol kinase catalytic domain (presumed) yegS - - - - - - - - - - - DAGK_cat k141_26374_2 218284.CCDN010000001_gene1628 6.68e-48 168.0 COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,4H9T9@91061|Bacilli,1ZBH0@1386|Bacillus 91061|Bacilli S YhgE Pip N-terminal domain protein pip - - ko:K01421 - - - - ko00000 - - - ABC2_membrane,ABC2_membrane_3,DUF3533 k141_8526_1 42565.FP66_02705 4.91e-141 405.0 COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,1RMNP@1236|Gammaproteobacteria,1XI4U@135619|Oceanospirillales 135619|Oceanospirillales L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria dnaN - 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3 k141_8526_2 42565.FP66_02700 3.36e-13 68.2 COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,1RNHP@1236|Gammaproteobacteria,1XHHN@135619|Oceanospirillales 135619|Oceanospirillales L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids dnaA - - ko:K02313 ko02020,ko04112,map02020,map04112 - - - ko00000,ko00001,ko03032,ko03036 - - - Bac_DnaA,Bac_DnaA_C,DnaA_N k141_36990_1 997296.PB1_06002 2.7e-86 259.0 COG2096@1|root,COG2096@2|Bacteria,1V3PI@1239|Firmicutes,4HH26@91061|Bacilli,1ZCJ1@1386|Bacillus 91061|Bacilli S Adenosyltransferase yvqK - 2.5.1.17 ko:K00798 ko00860,ko01100,map00860,map01100 M00122 R01492,R05220,R07268 RC00533 ko00000,ko00001,ko00002,ko01000 - - - Cob_adeno_trans k141_19169_2 1430440.MGMSRv2_0479 3.25e-09 56.2 COG3484@1|root,COG3484@2|Bacteria,1N057@1224|Proteobacteria,2U09K@28211|Alphaproteobacteria,2JRQ8@204441|Rhodospirillales 204441|Rhodospirillales O Proteasome-type protease - - - ko:K07395 - - - - ko00000 - - - Proteasome k141_6197_1 1116375.VEJY3_12345 7.82e-249 714.0 COG1330@1|root,COG1330@2|Bacteria,1MWTI@1224|Proteobacteria,1RNT0@1236|Gammaproteobacteria,1XTXU@135623|Vibrionales 135623|Vibrionales L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity recC - 3.1.11.5 ko:K03583 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_V_gamma k141_1326_1 1198452.Jab_2c09850 1.33e-58 183.0 COG0346@1|root,COG0346@2|Bacteria,1RH8Z@1224|Proteobacteria 1224|Proteobacteria E glyoxalase bleomycin resistance protein dioxygenase - - - - - - - - - - - - Glyoxalase k141_1326_2 1453501.JELR01000001_gene3271 2.77e-70 224.0 COG2267@1|root,COG2267@2|Bacteria,1R41P@1224|Proteobacteria,1T1IM@1236|Gammaproteobacteria,467KZ@72275|Alteromonadaceae 1236|Gammaproteobacteria I Serine aminopeptidase, S33 - - - - - - - - - - - - Abhydrolase_1 k141_26375_1 1384049.CD29_19170 2.2e-46 160.0 2EUS4@1|root,33N7Q@2|Bacteria,1VKV1@1239|Firmicutes,4HRK2@91061|Bacilli,3IZZD@400634|Lysinibacillus 91061|Bacilli S Toxin SpoIISA, type II toxin-antitoxin system - - - - - - - - - - - - SpoIISA_toxin k141_251_1 1280001.BAOA01000021_gene848 4.66e-147 430.0 COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,1RMVN@1236|Gammaproteobacteria,1XSTB@135623|Vibrionales 135623|Vibrionales M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source glmS GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 - R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 - - - GATase_6,SIS k141_29866_2 501479.ACNW01000050_gene3499 1.52e-94 276.0 COG0049@1|root,COG0049@2|Bacteria,1MXC8@1224|Proteobacteria,2TSI8@28211|Alphaproteobacteria 28211|Alphaproteobacteria J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA rpsG GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02992 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S7 k141_28762_1 218284.CCDN010000004_gene3039 5.41e-144 422.0 COG3428@1|root,COG3428@2|Bacteria,1TSRJ@1239|Firmicutes,4HB8P@91061|Bacilli,1ZBIF@1386|Bacillus 91061|Bacilli S Membrane ydbT - - ko:K08981 - - - - ko00000 - - - bPH_2 k141_22758_1 1279017.AQYJ01000022_gene2675 2.96e-140 398.0 COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,1RMG9@1236|Gammaproteobacteria,465AV@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) queC - 6.3.4.20 ko:K06920 ko00790,ko01100,map00790,map01100 - R09978 RC00959 ko00000,ko00001,ko01000,ko03016 - - - QueC k141_23920_1 218284.CCDN010000002_gene2710 1.57e-64 199.0 COG1393@1|root,COG1393@2|Bacteria,1V3QC@1239|Firmicutes,4HH0I@91061|Bacilli,1ZGP8@1386|Bacillus 91061|Bacilli K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress spxA - - ko:K16509 - - - - ko00000 - - - ArsC k141_23920_2 1307436.PBF_00075 2.31e-78 234.0 COG1959@1|root,COG1959@2|Bacteria,1VG7P@1239|Firmicutes,4HQBM@91061|Bacilli,1ZFIH@1386|Bacillus 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - Rrf2 k141_23920_3 1307436.PBF_00080 1.2e-41 139.0 2EAPX@1|root,334S8@2|Bacteria,1VHRM@1239|Firmicutes,4HQSW@91061|Bacilli,1ZJH1@1386|Bacillus 91061|Bacilli S IDEAL - - - - - - - - - - - - IDEAL k141_27490_1 1196031.ALEG01000031_gene2350 3.35e-120 352.0 COG0697@1|root,COG0697@2|Bacteria,1V2GJ@1239|Firmicutes,4HV8D@91061|Bacilli,1ZRP6@1386|Bacillus 91061|Bacilli EG EamA-like transporter family - - - - - - - - - - - - EamA k141_6198_1 406124.ACPC01000012_gene1116 3.36e-47 161.0 COG0552@1|root,COG0552@2|Bacteria,1TPRI@1239|Firmicutes,4HA6A@91061|Bacilli,1ZB46@1386|Bacillus 91061|Bacilli U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) ftsY - - ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2,3.A.5.7 - - SRP54,SRP54_N k141_6198_2 218284.CCDN010000001_gene24 1.28e-70 236.0 COG1196@1|root,COG1196@2|Bacteria,1TPJV@1239|Firmicutes,4HB89@91061|Bacilli,1ZAWM@1386|Bacillus 91061|Bacilli D Required for chromosome condensation and partitioning smc GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K03529 - - - - ko00000,ko03036 - - - SMC_N,SMC_hinge k141_18072_1 717606.PaecuDRAFT_4321 7.91e-69 218.0 COG2801@1|root,COG2801@2|Bacteria,1TQSP@1239|Firmicutes,4HET5@91061|Bacilli,26UIT@186822|Paenibacillaceae 91061|Bacilli L COG2801 Transposase and inactivated derivatives - - - ko:K07497 - - - - ko00000 - - - HTH_21,rve,rve_3 k141_19170_1 218284.CCDN010000005_gene3181 3.21e-54 182.0 COG4473@1|root,COG4473@2|Bacteria,1V1VG@1239|Firmicutes,4HG1K@91061|Bacilli,1ZBQG@1386|Bacillus 91061|Bacilli U ABC transporter ecsB - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - EcsB k141_19170_2 218284.CCDN010000005_gene3182 2.1e-27 106.0 28I6D@1|root,2Z89E@2|Bacteria,1TQNW@1239|Firmicutes,4HCGQ@91061|Bacilli,1ZAQM@1386|Bacillus 91061|Bacilli S EcsC protein family ecsC - - - - - - - - - - - EcsC k141_25110_1 223926.28807580 5.81e-51 166.0 COG1381@1|root,COG1381@2|Bacteria,1RHIC@1224|Proteobacteria,1RN8Y@1236|Gammaproteobacteria,1XU1R@135623|Vibrionales 135623|Vibrionales L Involved in DNA repair and RecF pathway recombination recO - - ko:K03584 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecO_C,RecO_N k141_25110_2 223926.28807581 2.39e-190 530.0 COG1159@1|root,COG1159@2|Bacteria,1MUKT@1224|Proteobacteria,1RN3A@1236|Gammaproteobacteria,1XUB4@135623|Vibrionales 135623|Vibrionales S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism era GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03595 - - - - ko00000,ko03009,ko03029 - - - KH_2,MMR_HSR1 k141_26376_1 883126.HMPREF9710_02120 5.14e-05 52.0 COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,2VHH5@28216|Betaproteobacteria,4732M@75682|Oxalobacteraceae 28216|Betaproteobacteria M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamB - - ko:K17713 - - - - ko00000,ko02000 1.B.33.1 - - PQQ_2,PQQ_3 k141_8527_1 1453501.JELR01000005_gene1647 3.97e-65 199.0 COG0346@1|root,COG0346@2|Bacteria,1N1HF@1224|Proteobacteria,1SFPY@1236|Gammaproteobacteria 1236|Gammaproteobacteria E lactoylglutathione lyase activity - - - - - - - - - - - - - k141_3777_1 1279017.AQYJ01000026_gene31 6.17e-164 497.0 COG4913@1|root,COG4913@2|Bacteria,1N16Z@1224|Proteobacteria,1RYVF@1236|Gammaproteobacteria,465ZJ@72275|Alteromonadaceae 1236|Gammaproteobacteria S Putative exonuclease SbcCD, C subunit - - - - - - - - - - - - AAA_29,SbcCD_C k141_32215_1 218284.CCDN010000001_gene690 4.86e-210 605.0 COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,4H9XC@91061|Bacilli,1ZB9E@1386|Bacillus 91061|Bacilli J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain alaS GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DHHA1,tRNA-synt_2c,tRNA_SAD k141_1327_2 1280001.BAOA01000217_gene259 1.51e-27 110.0 COG0318@1|root,COG0318@2|Bacteria,1MW0Y@1224|Proteobacteria,1RN35@1236|Gammaproteobacteria,1XTBP@135623|Vibrionales 135623|Vibrionales IQ O-succinylbenzoic acid--CoA ligase menE - 6.2.1.26 ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R04030 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - AMP-binding,AMP-binding_C k141_14463_1 1307436.PBF_22277 1.27e-71 233.0 COG1305@1|root,COG1305@2|Bacteria,1UYBU@1239|Firmicutes,4HBQQ@91061|Bacilli,1ZC8K@1386|Bacillus 91061|Bacilli E Transglutaminase-like superfamily - - - - - - - - - - - - Transglut_core k141_6200_1 309799.DICTH_1634 3.76e-53 177.0 COG1924@1|root,COG1924@2|Bacteria 2|Bacteria I 4 iron, 4 sulfur cluster binding hgdC_1 - - - - - - - - - - - BcrAD_BadFG,HGD-D k141_13278_2 218284.CCDN010000010_gene4397 1.02e-91 270.0 COG4463@1|root,COG4463@2|Bacteria,1VAXT@1239|Firmicutes,4HIFT@91061|Bacilli,1ZFR6@1386|Bacillus 91061|Bacilli K Belongs to the CtsR family ctsR GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 - ko:K03708 - - - - ko00000,ko03000 - - - CtsR k141_32216_2 1382306.JNIM01000001_gene543 1.27e-26 108.0 COG0003@1|root,COG0003@2|Bacteria,2G64V@200795|Chloroflexi 200795|Chloroflexi P PFAM Anion-transporting ATPase - - 3.6.3.16 ko:K01551 - - - - ko00000,ko01000,ko02000 3.A.19.1,3.A.21.1,3.A.4.1 - - ArsA_ATPase k141_15671_1 1453501.JELR01000002_gene996 1.74e-105 310.0 COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,1RMGV@1236|Gammaproteobacteria,464H0@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan dapF - 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 - - - DAP_epimerase k141_27492_1 42565.FP66_10900 2.65e-107 313.0 COG4598@1|root,COG4598@2|Bacteria,1QTS2@1224|Proteobacteria,1T249@1236|Gammaproteobacteria,1XNJ9@135619|Oceanospirillales 135619|Oceanospirillales E ATPases associated with a variety of cellular activities - - 3.6.3.21 ko:K02028 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran k141_27492_2 42565.FP66_10895 1.45e-13 68.6 COG0834@1|root,COG0834@2|Bacteria,1MXME@1224|Proteobacteria 1224|Proteobacteria ET belongs to the bacterial solute-binding protein 3 family - - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 k141_6201_1 218284.CCDN010000005_gene3485 5.76e-117 346.0 COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TPJ8@1239|Firmicutes,4HA8X@91061|Bacilli,1ZAZ3@1386|Bacillus 91061|Bacilli G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific nagE - 2.7.1.193,2.7.1.199 ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 M00267,M00809 R02738,R05199 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.13,4.A.1.1.14,4.A.1.1.15,4.A.1.1.2,4.A.1.1.5,4.A.1.1.7,4.A.1.1.9 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC k141_23922_1 1347369.CCAD010000068_gene3427 3.16e-08 50.4 29T50@1|root,30EBQ@2|Bacteria,1UCCY@1239|Firmicutes,4INVB@91061|Bacilli,1ZNZX@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_25113_1 1279017.AQYJ01000024_gene927 5.17e-56 189.0 COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,1RPNE@1236|Gammaproteobacteria,464ZH@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1022 Long-chain acyl-CoA synthetases (AMP-forming) - - - - - - - - - - - - AMP-binding k141_25113_2 313594.PI23P_03712 7.93e-12 64.3 COG1505@1|root,COG1505@2|Bacteria,4NFJS@976|Bacteroidetes,1HX9V@117743|Flavobacteriia,3VV9J@52959|Polaribacter 976|Bacteroidetes E Prolyl oligopeptidase, N-terminal beta-propeller domain pep GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.21.26 ko:K01322 ko04614,map04614 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S9,Peptidase_S9_N k141_2605_1 574375.BAGA_18190 9.63e-30 120.0 COG0601@1|root,COG0601@2|Bacteria,1VEBI@1239|Firmicutes,4HKXF@91061|Bacilli,1ZECG@1386|Bacillus 91061|Bacilli EP Binding-protein-dependent transport system inner membrane component - - - ko:K02033 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 k141_2605_2 198094.BA_2268 7.89e-21 95.1 COG1173@1|root,COG1173@2|Bacteria,1V21B@1239|Firmicutes,4HJ5Y@91061|Bacilli,1ZFPK@1386|Bacillus 91061|Bacilli EP ABC transporter (permease) - - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 k141_25150_1 1453501.JELR01000001_gene2283 2.55e-88 263.0 COG1376@1|root,COG1376@2|Bacteria,1Q823@1224|Proteobacteria 1224|Proteobacteria M ErfK ybiS ycfS ynhG family protein - - - - - - - - - - - - YkuD k141_19180_1 218284.CCDN010000004_gene3125 1.33e-17 82.4 COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,4HADT@91061|Bacilli,1ZCKV@1386|Bacillus 91061|Bacilli KT Sigma-54 interaction domain - - - - - - - - - - - - HTH_12,HTH_8,PAS,PAS_9,Sigma54_activat k141_19180_2 218284.CCDN010000004_gene3124 1.64e-56 181.0 COG0589@1|root,COG0589@2|Bacteria,1VH3X@1239|Firmicutes,4HNXN@91061|Bacilli,1ZCYJ@1386|Bacillus 91061|Bacilli T Universal stress protein nhaX - - - - - - - - - - - Usp k141_23952_1 218284.CCDN010000001_gene1115 7.8e-147 421.0 COG0337@1|root,COG0337@2|Bacteria,1TPKZ@1239|Firmicutes,4HAKN@91061|Bacilli,1ZC9C@1386|Bacillus 91061|Bacilli E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) aroB - 4.2.3.4 ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03083 RC00847 ko00000,ko00001,ko00002,ko01000 - - - DHQ_synthase k141_23952_2 218284.CCDN010000001_gene1114 8.88e-89 270.0 COG0082@1|root,COG0082@2|Bacteria,1TQ40@1239|Firmicutes,4HA0H@91061|Bacilli,1ZB2N@1386|Bacillus 91061|Bacilli E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system aroC GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01714 RC00586 ko00000,ko00001,ko00002,ko01000 - - - Chorismate_synt k141_26409_1 218284.CCDN010000001_gene516 4.41e-151 433.0 COG0628@1|root,COG0628@2|Bacteria,1TS4S@1239|Firmicutes,4HC6G@91061|Bacilli,1ZBXK@1386|Bacillus 91061|Bacilli S sporulation integral membrane protein YtvI ytvI GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - - - - - - - - - - AI-2E_transport k141_21635_1 218284.CCDN010000005_gene3196 1.85e-91 270.0 COG1309@1|root,COG1309@2|Bacteria,1V2H2@1239|Firmicutes,4HHJD@91061|Bacilli,1ZFYK@1386|Bacillus 91061|Bacilli K Transcriptional regulator yhgD GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - ko:K09017 - - - - ko00000,ko03000 - - - TetR_N k141_6232_1 1279017.AQYJ01000021_gene2819 6.13e-78 246.0 COG3004@1|root,COG3004@2|Bacteria,1MW15@1224|Proteobacteria,1RNDE@1236|Gammaproteobacteria,464UV@72275|Alteromonadaceae 1236|Gammaproteobacteria P ) H( ) antiporter that extrudes sodium in exchange for external protons nhaA - - ko:K03313 - - - - ko00000,ko02000 2.A.33.1 - - Na_H_antiport_1,Thioredoxin_4 k141_6232_2 1279017.AQYJ01000021_gene2818 5.65e-07 50.8 COG1189@1|root,COG1189@2|Bacteria,1MWP5@1224|Proteobacteria,1S28A@1236|Gammaproteobacteria,466PV@72275|Alteromonadaceae 1236|Gammaproteobacteria J FtsJ-like methyltransferase - - 2.1.1.226,2.1.1.227 ko:K06442 - - - - ko00000,ko01000,ko03009 - - - FtsJ,S4 k141_18092_2 218284.CCDN010000001_gene938 2.53e-155 439.0 2CH5D@1|root,2Z821@2|Bacteria,1TS45@1239|Firmicutes,4HCE9@91061|Bacilli,1ZAXP@1386|Bacillus 91061|Bacilli S Bacterial protein YqhG of unknown function yqhG - - - - - - - - - - - YqhG k141_18092_3 218284.CCDN010000001_gene939 9.79e-189 537.0 COG0553@1|root,COG0553@2|Bacteria,1TQ5E@1239|Firmicutes,4H9WB@91061|Bacilli,1ZAR5@1386|Bacillus 91061|Bacilli L COG0553 Superfamily II DNA RNA helicases, SNF2 family yqhH - - - - - - - - - - - Helicase_C,SNF2_N k141_12104_1 1294265.JCM21738_2971 6.2e-08 52.8 COG0803@1|root,COG0803@2|Bacteria,1TPG7@1239|Firmicutes,4H9UN@91061|Bacilli,1ZC2Z@1386|Bacillus 91061|Bacilli P Belongs to the bacterial solute-binding protein 9 family adcA - - ko:K09815,ko:K09818 ko02010,map02010 M00242,M00243 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 - - ZnuA k141_10855_1 1294265.JCM21738_2831 2.04e-86 256.0 COG0450@1|root,COG0450@2|Bacteria,1TQU7@1239|Firmicutes,4HA2M@91061|Bacilli,1ZCZP@1386|Bacillus 91061|Bacilli O Alkyl hydroperoxide reductase ahpC - 1.11.1.15 ko:K03386 ko04214,map04214 - - - ko00000,ko00001,ko01000,ko04147 - - - 1-cysPrx_C,AhpC-TSA k141_13301_1 42565.FP66_12890 4.09e-53 173.0 COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,1RP6E@1236|Gammaproteobacteria,1XH4I@135619|Oceanospirillales 135619|Oceanospirillales L TatD family tatD - - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase k141_13301_2 42565.FP66_12885 1.54e-57 181.0 COG3816@1|root,COG3816@2|Bacteria,1RD5Q@1224|Proteobacteria,1S9CC@1236|Gammaproteobacteria,1XJZZ@135619|Oceanospirillales 135619|Oceanospirillales S protein conserved in bacteria - - - ko:K09986 - - - - ko00000 - - - DUF1285 k141_23954_1 1453501.JELR01000002_gene1230 4.87e-45 152.0 COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,1RMFR@1236|Gammaproteobacteria,464GZ@72275|Alteromonadaceae 1236|Gammaproteobacteria K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes rpoH GO:0000150,GO:0000976,GO:0000984,GO:0000985,GO:0000988,GO:0000990,GO:0001017,GO:0001046,GO:0001047,GO:0001067,GO:0001121,GO:0001130,GO:0001131,GO:0001140,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006310,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009009,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031421,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140097,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2000142,GO:2001141 - ko:K03089 - - - - ko00000,ko03021 - - - Sigma70_r1_2,Sigma70_r2,Sigma70_r4 k141_16825_2 1051501.AYTL01000027_gene679 3.6e-21 84.3 2C7Y5@1|root,2ZW4E@2|Bacteria,1W5UC@1239|Firmicutes,4HZZW@91061|Bacilli,1ZJ0V@1386|Bacillus 91061|Bacilli S ComZ comZ - - ko:K02254 - - - - ko00000,ko02044 - - - ComZ k141_18093_2 1453501.JELR01000002_gene1264 7.81e-68 207.0 COG0139@1|root,COG0139@2|Bacteria,1MW67@1224|Proteobacteria,1RMV4@1236|Gammaproteobacteria,4679A@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP hisI GO:0000105,GO:0003674,GO:0003824,GO:0004635,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.4.19,3.6.1.31 ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035,R04037 RC00002,RC01055 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_5014 PRA-CH,PRA-PH k141_35814_2 935837.JAEK01000004_gene4756 2.57e-26 96.7 COG0267@1|root,COG0267@2|Bacteria,1VEJ4@1239|Firmicutes,4HNIM@91061|Bacilli,1ZIUS@1386|Bacillus 91061|Bacilli J Belongs to the bacterial ribosomal protein bL33 family rpmG - - ko:K02913 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L33 k141_31147_1 1295642.H839_10618 2.51e-48 169.0 COG1680@1|root,COG1680@2|Bacteria,1U828@1239|Firmicutes,4HA0Q@91061|Bacilli,1WEQ6@129337|Geobacillus 91061|Bacilli V Immune inhibitor A peptidase M6 estB - - - - - - - - - - - Beta-lactamase,Peptidase_M6 k141_33456_1 864702.OsccyDRAFT_0060 2.31e-95 323.0 COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1H9T8@1150|Oscillatoriales 1117|Cyanobacteria Q Amino acid adenylation domain - - - - - - - - - - - - AMP-binding,AMP-binding_C,Condensation,Methyltransf_12,NAD_binding_4,PP-binding,PilZ,Thioesterase k141_25153_1 218284.CCDN010000002_gene2258 2.84e-84 249.0 COG3871@1|root,COG3871@2|Bacteria,1V6MX@1239|Firmicutes,4HIYZ@91061|Bacilli,1ZH2Z@1386|Bacillus 91061|Bacilli S general stress protein ydaG - - - - - - - - - - - Putative_PNPOx,Pyrid_ox_like k141_20349_1 1347086.CCBA010000034_gene2720 1.32e-31 118.0 COG4122@1|root,COG4122@2|Bacteria,1UF4M@1239|Firmicutes,4HE9E@91061|Bacilli,1ZFK8@1386|Bacillus 91061|Bacilli S O-methyltransferase yrrM - 2.1.1.104 ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 M00039,M00350 R01942,R06578 RC00003,RC00392 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_3 k141_6235_1 218284.CCDN010000001_gene632 2.1e-91 281.0 COG1530@1|root,COG1530@2|Bacteria,1TQS4@1239|Firmicutes,4HC3Q@91061|Bacilli,1ZCCF@1386|Bacillus 91061|Bacilli J ribonuclease, Rne Rng family rng - - ko:K08301 - - - - ko00000,ko01000,ko03009,ko03019 - - - RNase_E_G,S1 k141_23955_2 240302.BN982_03150 8.18e-45 157.0 COG1215@1|root,COG1215@2|Bacteria,1TR2P@1239|Firmicutes,4HAQN@91061|Bacilli,3NF2W@45667|Halobacillus 91061|Bacilli M Glycosyl transferase family group 2 ica2 - - - - - - - - - - - Glyco_tranf_2_3,Glycos_transf_2 k141_11139_1 1279017.AQYJ01000027_gene1919 1.14e-68 216.0 COG1346@1|root,COG1346@2|Bacteria,1MV81@1224|Proteobacteria,1RS5C@1236|Gammaproteobacteria,4675Y@72275|Alteromonadaceae 1236|Gammaproteobacteria M effector of murein hydrolase yohK GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - LrgB k141_11139_2 1121943.KB899991_gene2368 1.69e-13 70.1 COG1380@1|root,COG1380@2|Bacteria,1N753@1224|Proteobacteria,1SDBW@1236|Gammaproteobacteria,1XM48@135619|Oceanospirillales 135619|Oceanospirillales S LrgA family - - - - - - - - - - - - LrgA k141_5185_1 218284.CCDN010000002_gene2236 3.86e-68 214.0 COG1295@1|root,COG1295@2|Bacteria,1U7HM@1239|Firmicutes,4H9MJ@91061|Bacilli,1ZCAD@1386|Bacillus 91061|Bacilli S Belongs to the UPF0761 family yihY - - ko:K07058 - - - - ko00000 - - - Virul_fac_BrkB k141_5185_2 218284.CCDN010000002_gene2235 1.22e-24 97.1 COG4980@1|root,COG4980@2|Bacteria,1VGY5@1239|Firmicutes,4HPNI@91061|Bacilli,1ZIVN@1386|Bacillus 91061|Bacilli S gas vesicle protein yfkI - - - - - - - - - - - - k141_33744_2 997296.PB1_01120 3.33e-27 102.0 COG1677@1|root,COG1677@2|Bacteria,1VEEY@1239|Firmicutes,4HNZW@91061|Bacilli,1ZIT0@1386|Bacillus 91061|Bacilli N Flagellar hook-basal body fliE - - ko:K02408 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FliE k141_33744_3 218284.CCDN010000001_gene1932 5.66e-82 258.0 COG1766@1|root,COG1766@2|Bacteria,1TRK0@1239|Firmicutes,4HBF0@91061|Bacilli,1ZAZN@1386|Bacillus 91061|Bacilli N The M ring may be actively involved in energy transduction fliF - - ko:K02409 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 - - YscJ_FliF,YscJ_FliF_C k141_547_1 1453501.JELR01000002_gene845 2.34e-103 314.0 COG0246@1|root,COG0246@2|Bacteria,1MVZ7@1224|Proteobacteria,1RNIZ@1236|Gammaproteobacteria,4641C@72275|Alteromonadaceae 1236|Gammaproteobacteria G COG0246 Mannitol-1-phosphate altronate dehydrogenases uxuB GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0006063,GO:0006064,GO:0006082,GO:0008150,GO:0008152,GO:0008866,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019585,GO:0019752,GO:0032787,GO:0042839,GO:0042840,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046365,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 1.1.1.57,1.1.1.67 ko:K00040,ko:K00045 ko00040,ko00051,ko01100,map00040,map00051,map01100 M00061 R00868,R02454 RC00085 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_2108,iECOK1_1307.ECOK1_4822,iUMN146_1321.UM146_22300,iUTI89_1310.UTI89_C5019 Mannitol_dh,Mannitol_dh_C k141_34870_1 671143.DAMO_0821 8.38e-73 230.0 COG1290@1|root,COG1290@2|Bacteria,2NP8C@2323|unclassified Bacteria 2|Bacteria C Cytochrome b(N-terminal)/b6/petB petB - - ko:K00410,ko:K00412,ko:K02635,ko:K02637 ko00190,ko00195,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map00195,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152,M00162 - - ko00000,ko00001,ko00002,ko00194,ko03029 - - - Cytochrom_B_C,Cytochrom_C1,Cytochrome_B k141_1550_1 1089551.KE386572_gene1513 1.09e-52 179.0 COG2114@1|root,COG2114@2|Bacteria,1N6I7@1224|Proteobacteria,2U3M0@28211|Alphaproteobacteria 28211|Alphaproteobacteria T Adenylate cyclase, family 3 (some proteins contain HAMP domain) - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - DUF4242,Guanylate_cyc k141_9970_1 218284.CCDN010000001_gene625 3.36e-197 550.0 COG1077@1|root,COG1077@2|Bacteria,1TP51@1239|Firmicutes,4HA4S@91061|Bacilli,1ZB43@1386|Bacillus 91061|Bacilli D Rod shape-determining protein MreB mreB - - ko:K03569 - - - - ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 - - MreB_Mbl k141_26773_1 981223.AIED01000006_gene3425 8.34e-53 177.0 28JZ9@1|root,2Z9PC@2|Bacteria,1R7GE@1224|Proteobacteria,1S7TF@1236|Gammaproteobacteria,3NM3I@468|Moraxellaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_21823_1 1207075.PputUW4_02582 2.75e-28 112.0 COG0760@1|root,COG0760@2|Bacteria,1R4ZR@1224|Proteobacteria,1SEDW@1236|Gammaproteobacteria 1236|Gammaproteobacteria O PPIC-type PPIASE domain - - - - - - - - - - - - Rotamase_2 k141_7502_1 218284.CCDN010000001_gene133 2.53e-109 325.0 COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,4HAEV@91061|Bacilli,1ZBDZ@1386|Bacillus 91061|Bacilli D Belongs to the SEDS family ftsW - - ko:K03588 ko04112,map04112 - - - ko00000,ko00001,ko02000,ko03036 2.A.103.1 - - FTSW_RODA_SPOVE k141_12451_1 1116375.VEJY3_17731 3.38e-227 627.0 COG2390@1|root,COG2390@2|Bacteria,1MX3F@1224|Proteobacteria,1RMEZ@1236|Gammaproteobacteria,1XT80@135623|Vibrionales 135623|Vibrionales K Transcriptional regulator, contains sigma factor-related N-terminal domain lsrR - - - - - - - - - - - HTH_28,Sugar-bind k141_12451_2 55601.VANGNB10_cII0556 9.14e-33 121.0 COG0176@1|root,COG0176@2|Bacteria,1MWQ8@1224|Proteobacteria,1RMS0@1236|Gammaproteobacteria,1XSNT@135623|Vibrionales 135623|Vibrionales F Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway tal GO:0003674,GO:0003824,GO:0004801,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009987,GO:0016740,GO:0016744,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 2.2.1.2 ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01827 RC00439,RC00604 ko00000,ko00001,ko00002,ko01000 - - - TAL_FSA k141_548_1 1347393.HG726029_gene2131 1.2e-11 60.1 arCOG05874@1|root,2ZJ01@2|Bacteria,4PK82@976|Bacteroidetes,2FU80@200643|Bacteroidia,4ASE0@815|Bacteroidaceae 976|Bacteroidetes - - - - - - - - - - - - - - - k141_30034_1 491952.Mar181_2523 5.84e-210 591.0 COG2072@1|root,COG2072@2|Bacteria,1MWPJ@1224|Proteobacteria,1RNQP@1236|Gammaproteobacteria 1236|Gammaproteobacteria P oxidoreductase - - - ko:K07222 - - - - ko00000 - - - Pyr_redox_3 k141_30034_2 491952.Mar181_2524 1.19e-87 258.0 COG0251@1|root,COG0251@2|Bacteria,1RAKQ@1224|Proteobacteria,1S2FK@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Endoribonuclease yabJ_1 - - - - - - - - - - - Ribonuc_L-PSP k141_30034_3 1220582.RRU01S_28_01110 8.97e-66 209.0 COG3342@1|root,COG3342@2|Bacteria,1MWQT@1224|Proteobacteria,2TRJZ@28211|Alphaproteobacteria,4BCS7@82115|Rhizobiaceae 28211|Alphaproteobacteria S Family of unknown function (DUF1028) - - - - - - - - - - - - DUF1028 k141_30034_4 491952.Mar181_2526 2.25e-142 411.0 COG0583@1|root,COG0583@2|Bacteria,1MU8N@1224|Proteobacteria,1RRVV@1236|Gammaproteobacteria,1XNHK@135619|Oceanospirillales 135619|Oceanospirillales K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate k141_5188_1 240016.ABIZ01000001_gene2046 2.18e-16 84.7 COG0471@1|root,COG0471@2|Bacteria,46TTA@74201|Verrucomicrobia,2IU1V@203494|Verrucomicrobiae 203494|Verrucomicrobiae P Citrate transporter - - - - - - - - - - - - CitMHS,TrkA_C k141_12452_1 558169.AGAV01000007_gene1326 1.86e-73 229.0 COG1230@1|root,COG1230@2|Bacteria,1TR92@1239|Firmicutes,4HBCQ@91061|Bacilli 91061|Bacilli P cation diffusion facilitator family transporter czcD - - ko:K16264 - - - - ko00000,ko02000 2.A.4.1 - - Cation_efflux,ZT_dimer k141_18317_1 1279017.AQYJ01000028_gene2405 8.71e-283 787.0 COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,1RMT7@1236|Gammaproteobacteria,466B9@72275|Alteromonadaceae 1236|Gammaproteobacteria S Bacterial protein of unknown function (DUF885) - - - - - - - - - - - - DUF885 k141_19442_1 330214.NIDE0637 1.43e-11 67.0 COG1228@1|root,COG1228@2|Bacteria 2|Bacteria Q imidazolonepropionase activity - - - ko:K07221 - - - - ko00000,ko02000 1.B.5.1 - - Amidohydro_1 k141_19442_3 1125863.JAFN01000001_gene207 1.93e-39 139.0 COG1028@1|root,COG1028@2|Bacteria,1QXA0@1224|Proteobacteria,42UQH@68525|delta/epsilon subdivisions,2WQ5R@28221|Deltaproteobacteria 28221|Deltaproteobacteria IQ Enoyl-(Acyl carrier protein) reductase - - - - - - - - - - - - adh_short_C2 k141_25433_1 1121090.KB894686_gene3130 2.75e-38 140.0 COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,4HB0C@91061|Bacilli,1ZBK5@1386|Bacillus 91061|Bacilli NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB comGA - - ko:K02243 - M00429 - - ko00000,ko00002,ko02044 3.A.14.1 - - T2SSE k141_5189_1 501479.ACNW01000057_gene4363 3.4e-39 133.0 COG0239@1|root,COG0239@2|Bacteria,1MZNH@1224|Proteobacteria,2UBUP@28211|Alphaproteobacteria 28211|Alphaproteobacteria D Important for reducing fluoride concentration in the cell, thus reducing its toxicity crcB - - ko:K06199 - - - - ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 - - CRCB k141_5189_2 501479.ACNW01000057_gene4362 2.49e-60 195.0 COG0564@1|root,COG0564@2|Bacteria,1MVDX@1224|Proteobacteria,2TTQC@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Responsible for synthesis of pseudouridine from uracil rluC GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.24 ko:K06179 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 k141_12453_1 1294265.JCM21738_4739 4.49e-124 360.0 COG0365@1|root,COG0365@2|Bacteria,1TQTI@1239|Firmicutes,4H9PN@91061|Bacilli,1ZBDX@1386|Bacillus 91061|Bacilli I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases acsA - 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 - - - AMP-binding,AMP-binding_C k141_9973_1 240302.BN982_00571 3.32e-76 239.0 COG0301@1|root,COG0301@2|Bacteria,1TPNW@1239|Firmicutes,4HAV9@91061|Bacilli,3ND3E@45667|Halobacillus 91061|Bacilli H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS thiI - 2.8.1.4 ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07461 - ko00000,ko00001,ko01000,ko03016 - - - THUMP,ThiI k141_549_1 1294265.JCM21738_2869 9.44e-25 98.2 COG4709@1|root,COG4709@2|Bacteria,1VEVX@1239|Firmicutes,4HP5D@91061|Bacilli,1ZIJI@1386|Bacillus 91061|Bacilli S membrane yqfX - - - - - - - - - - - - k141_549_2 1294265.JCM21738_2868 2.28e-59 186.0 COG5663@1|root,COG5663@2|Bacteria,1V2IT@1239|Firmicutes,4HG86@91061|Bacilli,1ZDPA@1386|Bacillus 91061|Bacilli S Belongs to the 5'(3')-deoxyribonucleotidase family yqfW - - ko:K05967 - - - - ko00000 - - - NT5C k141_20578_1 1279017.AQYJ01000024_gene933 2.02e-77 236.0 2E3UE@1|root,32YRS@2|Bacteria 2|Bacteria S Protein of unknown function (DUF2799) - - - - - - - - - - - - DUF2799 k141_20578_2 298386.PBPRA1917 4.17e-94 279.0 COG1896@1|root,COG1896@2|Bacteria,1MXEZ@1224|Proteobacteria,1RRQQ@1236|Gammaproteobacteria,1XUSC@135623|Vibrionales 135623|Vibrionales S hydrolases of HD superfamily - - - ko:K07023 - - - - ko00000 - - - HD_3 k141_20578_3 382245.ASA_0530 2.94e-70 214.0 COG3791@1|root,COG3791@2|Bacteria,1RHWZ@1224|Proteobacteria,1S4HQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Glutathione-dependent formaldehyde-activating - - - - - - - - - - - - GFA k141_20578_4 1453501.JELR01000002_gene121 1.69e-176 500.0 COG2055@1|root,COG2055@2|Bacteria,1MWQY@1224|Proteobacteria,1RSKW@1236|Gammaproteobacteria,4685W@72275|Alteromonadaceae 1236|Gammaproteobacteria C Malate/L-lactate dehydrogenase - - - - - - - - - - - - Ldh_2 k141_20578_5 1453501.JELR01000002_gene122 2.16e-56 179.0 COG1186@1|root,COG1186@2|Bacteria,1RH75@1224|Proteobacteria,1S5YQ@1236|Gammaproteobacteria,4678H@72275|Alteromonadaceae 1236|Gammaproteobacteria J COG1186 Protein chain release factor B yaeJ GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 - ko:K15034 - - - - ko00000,ko03012 - - - RF-1 k141_20578_6 745411.B3C1_06869 5.33e-21 94.0 COG1292@1|root,COG1292@2|Bacteria,1MV0K@1224|Proteobacteria,1RP3E@1236|Gammaproteobacteria,1J5HD@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria U Belongs to the BCCT transporter (TC 2.A.15) family betT - - ko:K02168 - - - - ko00000,ko02000 2.A.15.1.3,2.A.15.1.4 - - BCCT k141_9974_1 1116375.VEJY3_13945 8.04e-136 401.0 COG0369@1|root,COG0369@2|Bacteria,1QUAH@1224|Proteobacteria,1T1RJ@1236|Gammaproteobacteria,1XT6J@135623|Vibrionales 135623|Vibrionales P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component cysJ - 1.8.1.2 ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00176 R00858 RC00065 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_1,Flavodoxin_1,NAD_binding_1 k141_12454_1 1461580.CCAS010000006_gene970 5.85e-68 207.0 COG0292@1|root,COG0292@2|Bacteria,1V6DB@1239|Firmicutes,4HH2W@91061|Bacilli,1ZG75@1386|Bacillus 91061|Bacilli J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit rplT GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - ko:K02887 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L20 k141_32404_1 768066.HELO_2287 8.62e-150 424.0 COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,1RMJF@1236|Gammaproteobacteria,1XH28@135619|Oceanospirillales 135619|Oceanospirillales D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP mrp - - ko:K03593 - - - - ko00000,ko03029,ko03036 - - - FeS_assembly_P,ParA k141_26775_1 218284.CCDN010000002_gene2583 1.02e-159 460.0 COG0642@1|root,COG2205@2|Bacteria,1V10X@1239|Firmicutes,4HAU7@91061|Bacilli,1ZB6A@1386|Bacillus 91061|Bacilli T Histidine kinase - - - - - - - - - - - - HAMP,HATPase_c,HisKA k141_26775_2 218284.CCDN010000002_gene2584 4.8e-102 301.0 COG0745@1|root,COG0745@2|Bacteria,1TPN8@1239|Firmicutes,4HFU2@91061|Bacilli,1ZG3V@1386|Bacillus 91061|Bacilli T Transcriptional regulatory protein, C terminal - - - - - - - - - - - - Response_reg,Trans_reg_C k141_12455_2 218284.CCDN010000001_gene1164 9.06e-22 93.2 COG1199@1|root,COG1199@2|Bacteria,1TRNV@1239|Firmicutes,4HBYD@91061|Bacilli,1ZARY@1386|Bacillus 91061|Bacilli KL COG1199 Rad3-related DNA helicases ypvA - 3.6.4.12 ko:K03722 - - - - ko00000,ko01000,ko03400 - - - Helicase_C_2 k141_18319_1 392500.Swoo_1143 1.13e-66 220.0 COG0665@1|root,COG0665@2|Bacteria,1MU40@1224|Proteobacteria,1RMJY@1236|Gammaproteobacteria,2QAJQ@267890|Shewanellaceae 1236|Gammaproteobacteria E PFAM tryptophan halogenase prnA - 1.14.19.9 ko:K14266 ko00404,ko01130,map00404,map01130 M00789,M00790 R09570 RC00949 ko00000,ko00001,ko00002,ko01000 - - - Trp_halogenase k141_5192_1 218284.CCDN010000002_gene2758 1.35e-97 306.0 COG0577@1|root,COG0577@2|Bacteria,1TPHU@1239|Firmicutes,4HA2C@91061|Bacilli,1ZG12@1386|Bacillus 91061|Bacilli V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX k141_25434_1 234267.Acid_0447 6.24e-126 370.0 COG2159@1|root,COG2159@2|Bacteria,3Y7DZ@57723|Acidobacteria 57723|Acidobacteria S PFAM amidohydrolase - - - - - - - - - - - - Amidohydro_2 k141_37206_1 218284.CCDN010000007_gene3911 8.21e-39 141.0 COG1292@1|root,COG1292@2|Bacteria,1TRS6@1239|Firmicutes,4HA7U@91061|Bacilli,1ZBRN@1386|Bacillus 91061|Bacilli M Belongs to the BCCT transporter (TC 2.A.15) family opuD_3 - - - - - - - - - - - BCCT k141_37206_2 218284.CCDN010000007_gene3912 2.99e-06 49.3 COG0561@1|root,COG0561@2|Bacteria,1V5FB@1239|Firmicutes,4HGY8@91061|Bacilli,1ZDBI@1386|Bacillus 91061|Bacilli S hydrolases of the HAD superfamily ycsE - - - - - - - - - - - Hydrolase_3 k141_34875_1 1307436.PBF_18804 2.69e-84 258.0 COG1270@1|root,COG1270@2|Bacteria,1TQ3X@1239|Firmicutes,4HA48@91061|Bacilli,1ZCDR@1386|Bacillus 91061|Bacilli H Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group cobD - 6.3.1.10 ko:K02227 ko00860,ko01100,map00860,map01100 M00122 R06529,R07302 RC00090,RC00096 ko00000,ko00001,ko00002,ko01000 - - - CobD_Cbib k141_4064_2 768066.HELO_1440 2.08e-74 224.0 COG3607@1|root,COG3607@2|Bacteria,1RH1T@1224|Proteobacteria,1S6XB@1236|Gammaproteobacteria,1XK53@135619|Oceanospirillales 135619|Oceanospirillales S Lactoylglutathione lyase - - - ko:K07032 - - - - ko00000 - - - - k141_4064_3 203122.Sde_3319 3.13e-19 80.9 COG3795@1|root,COG3795@2|Bacteria,1N32U@1224|Proteobacteria,1S82G@1236|Gammaproteobacteria,467IZ@72275|Alteromonadaceae 1236|Gammaproteobacteria S YCII-related domain - - - - - - - - - - - - YCII k141_5193_1 218284.CCDN010000001_gene1964 6.1e-79 239.0 COG3382@1|root,COG3382@2|Bacteria,1V7YR@1239|Firmicutes,4HGDN@91061|Bacilli,1ZBT2@1386|Bacillus 91061|Bacilli S B3/4 domain yhzB - - - - - - - - - - - B3_4 k141_25435_1 319224.Sputcn32_2060 3.93e-38 139.0 COG2017@1|root,COG2017@2|Bacteria,1MVMN@1224|Proteobacteria,1RNZN@1236|Gammaproteobacteria,2QD9A@267890|Shewanellaceae 1236|Gammaproteobacteria G Converts alpha-aldose to the beta-anomer galM - 5.1.3.3 ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 M00632 R01602,R10619 RC00563 ko00000,ko00001,ko00002,ko01000 - - - Aldose_epim k141_20579_1 1157490.EL26_24370 1.36e-69 211.0 COG0346@1|root,COG0346@2|Bacteria,1VE9K@1239|Firmicutes,4HMMH@91061|Bacilli 91061|Bacilli E glyoxalase - - - - - - - - - - - - Glyoxalase_2 k141_20579_2 1501230.ET33_13020 3.84e-67 206.0 COG1959@1|root,COG1959@2|Bacteria,1V6NZ@1239|Firmicutes,4HK9P@91061|Bacilli,26XV7@186822|Paenibacillaceae 91061|Bacilli K Transcriptional regulator ywgB - - - - - - - - - - - Rrf2 k141_23088_1 1453501.JELR01000002_gene866 2.18e-15 76.3 COG0457@1|root,COG0457@2|Bacteria,1NAJI@1224|Proteobacteria 1224|Proteobacteria T ATPase activity - - - - - - - - - - - - DUF1570 k141_23088_3 1123034.JMKP01000014_gene568 1.52e-111 332.0 COG2267@1|root,COG2267@2|Bacteria,1QYEP@1224|Proteobacteria,1T3P8@1236|Gammaproteobacteria,3NTTP@468|Moraxellaceae 1236|Gammaproteobacteria I Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_1 k141_1555_1 218284.CCDN010000001_gene1431 9.93e-62 189.0 COG0607@1|root,COG0607@2|Bacteria,1VES3@1239|Firmicutes,4HNRE@91061|Bacilli,1ZI0X@1386|Bacillus 91061|Bacilli P Rhodanese domain protein - - - - - - - - - - - - Rhodanese k141_14645_1 1279017.AQYJ01000027_gene1598 7.76e-11 60.5 COG1678@1|root,COG1678@2|Bacteria,1RCXM@1224|Proteobacteria,1S3YV@1236|Gammaproteobacteria,466MP@72275|Alteromonadaceae 1236|Gammaproteobacteria K Belongs to the UPF0301 (AlgH) family yqgE GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K07735 - - - - ko00000,ko03000 - - - DUF179 k141_1573_2 315750.BPUM_1461 8.14e-25 99.8 COG2138@1|root,COG2138@2|Bacteria,1TRDV@1239|Firmicutes,4H9RT@91061|Bacilli,1ZGH1@1386|Bacillus 91061|Bacilli S Sirohydrochlorin ferrochelatase sirB - 4.99.1.4 ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R02864 RC01012 ko00000,ko00001,ko00002,ko01000 - - - CbiX k141_14661_1 104623.Ser39006_02384 3.26e-46 156.0 COG1595@1|root,COG1595@2|Bacteria,1RHKM@1224|Proteobacteria,1S48U@1236|Gammaproteobacteria,40519@613|Serratia 1236|Gammaproteobacteria K Belongs to the sigma-70 factor family. ECF subfamily rpoE - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_14661_2 1279017.AQYJ01000021_gene2929 2.34e-115 336.0 COG1028@1|root,COG1028@2|Bacteria,1RHYX@1224|Proteobacteria,1S0GN@1236|Gammaproteobacteria,46D27@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) csgA - - - - - - - - - - - adh_short k141_14661_3 1453501.JELR01000001_gene1872 4.33e-48 155.0 2CHAX@1|root,32ZC9@2|Bacteria,1N6X2@1224|Proteobacteria,1SCXD@1236|Gammaproteobacteria,468RC@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF3301) - - - - - - - - - - - - DUF3301 k141_14661_4 641147.HMPREF9021_00349 8.37e-27 99.8 COG4728@1|root,COG4728@2|Bacteria,1N6NP@1224|Proteobacteria,2VVVS@28216|Betaproteobacteria,2KRY4@206351|Neisseriales 206351|Neisseriales S Protein of unknown function (DUF1653) - - - - - - - - - - - - DUF1653 k141_26798_1 42565.FP66_02450 5.58e-126 378.0 COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,1RNJI@1236|Gammaproteobacteria,1XIU4@135619|Oceanospirillales 135619|Oceanospirillales L Unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present uvrD - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C k141_566_2 1121937.AUHJ01000017_gene2985 2.19e-158 455.0 COG3713@1|root,COG4704@1|root,COG3713@2|Bacteria,COG4704@2|Bacteria 2|Bacteria M MltA-interacting MipA family protein mipA - - ko:K07274 - - - - ko00000,ko02000 9.B.99.1 - - DUF2141,MipA k141_36003_1 1255043.TVNIR_3135 3.12e-83 272.0 COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,1RPIU@1236|Gammaproteobacteria,1WVW8@135613|Chromatiales 135613|Chromatiales EF Belongs to the CarB family carB - 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS k141_11175_2 261726.Q6R4V3_9CAUD 8.69e-27 108.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QJPJ@10662|Myoviridae 10662|Myoviridae S N-acetylmuramoyl-L-alanine amidase activity - GO:0005575,GO:0019012 - - - - - - - - - - - k141_23115_1 1453501.JELR01000001_gene1916 1.43e-83 262.0 COG1354@1|root,COG1354@2|Bacteria,1MVCN@1224|Proteobacteria,1RNBB@1236|Gammaproteobacteria,465A1@72275|Alteromonadaceae 1236|Gammaproteobacteria D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves scpA - - ko:K05896 - - - - ko00000,ko03036 - - - SMC_ScpA k141_4081_1 1121090.KB894697_gene1990 3.8e-98 298.0 COG1292@1|root,COG1292@2|Bacteria,1TRS6@1239|Firmicutes,4HA7U@91061|Bacilli,1ZBRN@1386|Bacillus 91061|Bacilli M Belongs to the BCCT transporter (TC 2.A.15) family opuD GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0016020,GO:0031460,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0072337 - ko:K05020 - - - - ko00000,ko02000 2.A.15.1.1,2.A.15.1.11 - iYO844.BSU30070 BCCT k141_32424_1 236097.ADG881_190 3.8e-50 167.0 COG1806@1|root,COG1806@2|Bacteria,1MUHU@1224|Proteobacteria,1RPHX@1236|Gammaproteobacteria,1XHER@135619|Oceanospirillales 135619|Oceanospirillales S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation - - 2.7.11.33,2.7.4.28 ko:K09773 - - - - ko00000,ko01000 - - - Kinase-PPPase k141_9991_1 1279017.AQYJ01000028_gene2464 1.63e-73 244.0 COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,1RNKN@1236|Gammaproteobacteria,463YS@72275|Alteromonadaceae 1236|Gammaproteobacteria CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit mnhA - - ko:K05565 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - DUF4040,MnhB,Proton_antipo_M,Proton_antipo_N k141_17064_1 218284.CCDN010000003_gene2969 1.83e-79 242.0 COG4123@1|root,COG4123@2|Bacteria,1TQ25@1239|Firmicutes,4HA8W@91061|Bacilli,1ZCBX@1386|Bacillus 91061|Bacilli S Conserved hypothetical protein 95 yabB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.223 ko:K07461,ko:K15460 - - - - ko00000,ko01000,ko03016 - - - GIY-YIG,MTS k141_2777_1 1323663.AROI01000009_gene3709 5.13e-32 119.0 COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,1RMSS@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_int_SAM_4,Phage_integrase k141_7525_1 218284.CCDN010000001_gene616 7.34e-96 290.0 COG1459@1|root,COG1459@2|Bacteria,1TQRZ@1239|Firmicutes,4HBFI@91061|Bacilli,1ZD1H@1386|Bacillus 91061|Bacilli NU type II secretion system pilC - - ko:K02653 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSF k141_26799_1 933115.GPDM_04519 7.31e-33 127.0 COG0397@1|root,COG0397@2|Bacteria,1TQXD@1239|Firmicutes,4HBKH@91061|Bacilli,26DJ4@186818|Planococcaceae 91061|Bacilli S Belongs to the UPF0061 (SELO) family M1-1044 - - - - - - - - - - - UPF0061 k141_26799_2 218284.CCDN010000002_gene2755 4.52e-19 83.2 COG1335@1|root,COG1335@2|Bacteria,1V0RD@1239|Firmicutes,4HD8Z@91061|Bacilli,1ZFUY@1386|Bacillus 91061|Bacilli Q isochorismatase - - - - - - - - - - - - Isochorismatase k141_14662_1 123214.PERMA_0871 5.41e-29 113.0 COG1060@1|root,COG1060@2|Bacteria,2G3M7@200783|Aquificae 200783|Aquificae H Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate mqnE - 2.5.1.120 ko:K18285 ko00130,ko01110,map00130,map01110 - R10667 RC00021,RC03234 ko00000,ko00001,ko01000 - - - Fer4_14,Radical_SAM k141_567_1 1397528.Q671_02715 3.23e-12 71.6 COG2885@1|root,COG2885@2|Bacteria,1RENP@1224|Proteobacteria,1S4IW@1236|Gammaproteobacteria,1XJ8G@135619|Oceanospirillales 135619|Oceanospirillales M Belongs to the ompA family oprF - - ko:K03286 - - - - ko00000,ko02000 1.B.6 - - OMP_b-brl,OmpA,TSP_3 k141_19463_1 935836.JAEL01000014_gene2073 2.89e-105 312.0 COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,4HBED@91061|Bacilli,1ZBXY@1386|Bacillus 91061|Bacilli EP COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components - - - ko:K02033 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 k141_19463_2 935836.JAEL01000014_gene2072 1.44e-74 230.0 COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4HBB9@91061|Bacilli,1ZC1H@1386|Bacillus 91061|Bacilli EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components - - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1,OppC_N k141_30056_2 218284.CCDN010000001_gene31 6.62e-71 231.0 COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,4HAWN@91061|Bacilli,1ZC17@1386|Bacillus 91061|Bacilli L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) recG GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecG_wedge k141_9033_6 1280001.BAOA01000128_gene1227 5.15e-178 497.0 COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,1RMGN@1236|Gammaproteobacteria,1XTDE@135623|Vibrionales 135623|Vibrionales E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate trpA GO:0000162,GO:0003674,GO:0003824,GO:0004834,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - Trp_syntA k141_9033_7 1116375.VEJY3_10285 7.32e-150 423.0 COG0664@1|root,COG0664@2|Bacteria,1QTPY@1224|Proteobacteria,1RXUD@1236|Gammaproteobacteria,1XZPQ@135623|Vibrionales 135623|Vibrionales K Crp-like helix-turn-helix domain - - - ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 - - - ko00000,ko00001,ko03000 - - - HTH_Crp_2,cNMP_binding k141_9033_8 1116375.VEJY3_10290 4.59e-290 798.0 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1RMQ4@1236|Gammaproteobacteria,1XV4V@135623|Vibrionales 135623|Vibrionales IQ AMP-binding enzyme C-terminal domain - - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding,AMP-binding_C k141_35177_1 218284.CCDN010000001_gene1167 2.2e-121 361.0 COG0843@1|root,COG0843@2|Bacteria,1TPZC@1239|Firmicutes,4HAHT@91061|Bacilli,1ZC76@1386|Bacillus 91061|Bacilli C COG0843 Heme copper-type cytochrome quinol oxidases, subunit 1 cbaA - 1.9.3.1 ko:K02274 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6 - - COX1 k141_780_1 1279017.AQYJ01000022_gene2749 6.02e-141 409.0 COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,1RMGP@1236|Gammaproteobacteria,46472@72275|Alteromonadaceae 1236|Gammaproteobacteria C FAD dependent oxidoreductase eryB - 1.1.5.3 ko:K00111 ko00564,ko01110,map00564,map01110 - R00848 RC00029 ko00000,ko00001,ko01000 - - - DAO,DAO_C k141_37385_1 1283337.B0ZSH0_BPHA1 2.2e-48 164.0 4QDWB@10239|Viruses,4QXAA@35237|dsDNA viruses no RNA stage,4QRZ6@28883|Caudovirales,4QIYA@10662|Myoviridae 10662|Myoviridae S Pfam:Phage_TAC_7 - - - - - - - - - - - - - k141_12728_1 218284.CCDN010000003_gene2973 3.09e-168 471.0 COG0084@1|root,COG0084@2|Bacteria,1TNY1@1239|Firmicutes,4HA74@91061|Bacilli,1ZB78@1386|Bacillus 91061|Bacilli L hydrolase, TatD tatD GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase k141_12728_2 1444310.JANV01000121_gene1295 3.9e-54 186.0 COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1TPA1@1239|Firmicutes,4H9VC@91061|Bacilli,1ZASP@1386|Bacillus 91061|Bacilli J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation metG GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1g,tRNA_bind k141_781_1 1294265.JCM21738_532 7.89e-32 117.0 COG0514@1|root,COG0514@2|Bacteria 2|Bacteria L ATP-dependent DNA helicase (RecQ) - - 3.6.4.12 ko:K03654,ko:K03657 ko03018,ko03420,ko03430,map03018,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,HRDC,Helicase_C,Helicase_C_2,NERD,RQC,RecQ_Zn_bind,UvrD-helicase,UvrD_C,zf-trcl k141_781_2 935836.JAEL01000107_gene2271 2.88e-19 82.0 COG0640@1|root,COG0640@2|Bacteria,1VMDM@1239|Firmicutes,4HYQV@91061|Bacilli,1ZGEU@1386|Bacillus 91061|Bacilli K Helix-turn-helix domain - - - - - - - - - - - - HTH_20,HTH_5 k141_32611_1 1123073.KB899242_gene973 9.51e-17 81.6 COG2976@1|root,COG2976@2|Bacteria,1N117@1224|Proteobacteria,1S95P@1236|Gammaproteobacteria,1X733@135614|Xanthomonadales 135614|Xanthomonadales S protein conserved in bacteria - - - - - - - - - - - - TPR_21 k141_5513_1 1219076.N646_2626 0.0 1689.0 COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,1RPIU@1236|Gammaproteobacteria,1XSNU@135623|Vibrionales 135623|Vibrionales F Carbamoyl-phosphate synthetase ammonia chain carB GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0034641,GO:0034654,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046390,GO:0046394,GO:0046483,GO:0055086,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS k141_5513_2 1219076.N646_2625 2.04e-274 750.0 COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,1RMAW@1236|Gammaproteobacteria,1XV0G@135623|Vibrionales 135623|Vibrionales F carbamoyl-phosphate synthetase glutamine chain carA GO:0000050,GO:0003674,GO:0003824,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006139,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0032991,GO:0034641,GO:0034654,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046394,GO:0046483,GO:0055086,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_sm_chain,GATase k141_5513_3 1116375.VEJY3_02125 2.57e-183 511.0 COG0289@1|root,COG0289@2|Bacteria,1MUCT@1224|Proteobacteria,1RMCZ@1236|Gammaproteobacteria,1XU3A@135623|Vibrionales 135623|Vibrionales E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate dapB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.17.1.8 ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R04198,R04199 RC00478 ko00000,ko00001,ko00002,ko01000 - - - DapB_C,DapB_N k141_5513_4 1116375.VEJY3_02120 5.8e-86 253.0 COG0494@1|root,COG0494@2|Bacteria,1RCZM@1224|Proteobacteria,1RS3S@1236|Gammaproteobacteria,1XXA4@135623|Vibrionales 135623|Vibrionales L Belongs to the Nudix hydrolase family mutT - 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - - NUDIX k141_5513_5 1116375.VEJY3_02115 0.0 1657.0 COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,1RM9M@1236|Gammaproteobacteria,1XTFQ@135623|Vibrionales 135623|Vibrionales U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW k141_5513_6 1116375.VEJY3_02110 1.71e-93 274.0 COG4701@1|root,COG4701@2|Bacteria,1NHRC@1224|Proteobacteria,1S15U@1236|Gammaproteobacteria,1XY04@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria - - - - - - - - - - - - DUF721 k141_5513_7 1116375.VEJY3_02105 2.28e-220 607.0 COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,1RQ72@1236|Gammaproteobacteria,1XU76@135623|Vibrionales 135623|Vibrionales M Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis lpxC GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008759,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.5.1.108 ko:K02535 ko00540,ko01100,map00540,map01100 M00060 R04587 RC00166,RC00300 ko00000,ko00001,ko00002,ko01000,ko01005 - - - LpxC k141_5513_8 1219076.N646_2619 8.48e-256 706.0 COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,1RPZS@1236|Gammaproteobacteria,1XTKI@135623|Vibrionales 135623|Vibrionales D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity ftsZ - - ko:K03531 ko04112,map04112 - - - ko00000,ko00001,ko02048,ko03036,ko04812 - - - FtsZ_C,Tubulin k141_5513_9 674977.VMC_28720 4.16e-297 811.0 COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,1RMXY@1236|Gammaproteobacteria,1XVP9@135623|Vibrionales 135623|Vibrionales D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring ftsA - - ko:K03590 ko04112,map04112 - - - ko00000,ko00001,ko03036,ko04812 - - - FtsA,SHS2_FTSA k141_5513_10 1116375.VEJY3_02090 1.67e-173 486.0 COG1589@1|root,COG1589@2|Bacteria,1N0T7@1224|Proteobacteria,1S9FJ@1236|Gammaproteobacteria,1XTAJ@135623|Vibrionales 135623|Vibrionales D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly ftsQ - - ko:K03589 ko04112,map04112 - - - ko00000,ko00001,ko03036 - - - FtsQ,POTRA_1 k141_6617_1 223926.28807914 9.07e-165 471.0 COG2199@1|root,COG2199@2|Bacteria,1NV1F@1224|Proteobacteria,1T39K@1236|Gammaproteobacteria,1XV76@135623|Vibrionales 135623|Vibrionales T Sensory box GGDEF family protein - - - - - - - - - - - - GGDEF,PAS_4 k141_6617_2 1280001.BAOA01000011_gene4235 6.25e-60 185.0 COG2901@1|root,COG2901@2|Bacteria,1N7MJ@1224|Proteobacteria,1SD35@1236|Gammaproteobacteria,1XXSR@135623|Vibrionales 135623|Vibrionales K Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters fis GO:0000229,GO:0000785,GO:0000786,GO:0000787,GO:0000789,GO:0003674,GO:0003700,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032991,GO:0032993,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044422,GO:0044424,GO:0044427,GO:0044444,GO:0044446,GO:0044464,GO:0044815,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 - ko:K03557 ko05111,map05111 - - - ko00000,ko00001,ko03000,ko03036,ko03400 - - - HTH_8 k141_6617_3 1116375.VEJY3_14645 1.63e-222 613.0 COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,1RMJP@1236|Gammaproteobacteria,1XV75@135623|Vibrionales 135623|Vibrionales J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines dusB - - ko:K05540 - - - - ko00000,ko01000,ko03016 - - - Dus k141_6617_4 1116375.VEJY3_14640 1.87e-214 592.0 COG2264@1|root,COG2264@2|Bacteria,1MUPC@1224|Proteobacteria,1RNAR@1236|Gammaproteobacteria,1XTMC@135623|Vibrionales 135623|Vibrionales J Methylates ribosomal protein L11 prmA - - ko:K02687 - - - - ko00000,ko01000,ko03009 - - - PrmA k141_6617_5 223926.28807907 0.0 892.0 COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,1RMNB@1236|Gammaproteobacteria,1XSFE@135623|Vibrionales 135623|Vibrionales I Biotin carboxylase accC - 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 k141_6617_6 1219077.VAZ01S_053_00440 1.6e-69 213.0 COG0511@1|root,COG0511@2|Bacteria,1RCXA@1224|Proteobacteria,1S3YP@1236|Gammaproteobacteria,1XWV0@135623|Vibrionales 135623|Vibrionales I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA accB - - ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742 RC00040,RC00367 ko00000,ko00001,ko00002 - - - Biotin_lipoyl k141_6617_7 223926.28807905 3.47e-97 283.0 COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,1S3PX@1236|Gammaproteobacteria,1XWVA@135623|Vibrionales 135623|Vibrionales E Catalyzes a trans-dehydration via an enolate intermediate aroQ GO:0003674,GO:0003824,GO:0003855,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 4.2.1.10 ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03084 RC00848 ko00000,ko00001,ko00002,ko01000 - - - DHquinase_II k141_6617_8 1116375.VEJY3_14620 0.0 1306.0 COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,1RMNZ@1236|Gammaproteobacteria,1XUS0@135623|Vibrionales 135623|Vibrionales F Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA acsA GO:0003674,GO:0003824,GO:0003987,GO:0006082,GO:0006083,GO:0006084,GO:0006085,GO:0006139,GO:0006163,GO:0006164,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0018130,GO:0019427,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACAS_N,AMP-binding,AMP-binding_C k141_6617_9 1116375.VEJY3_14615 2.15e-143 405.0 COG0847@1|root,COG0847@2|Bacteria,1P0GY@1224|Proteobacteria,1S6UR@1236|Gammaproteobacteria,1XTD3@135623|Vibrionales 135623|Vibrionales L DNA polymerase III, epsilon subunit - - 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - RNase_T k141_6617_10 1116375.VEJY3_14610 0.0 1116.0 COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,1RPSJ@1236|Gammaproteobacteria,1XTQS@135623|Vibrionales 135623|Vibrionales T containing cAMP-binding and CBS domains - - - ko:K07182 - - - - ko00000 - - - CBS,DUF294,DUF294_C,cNMP_binding k141_6617_11 1116375.VEJY3_14605 1.55e-257 709.0 COG0477@1|root,COG2814@2|Bacteria,1MVZI@1224|Proteobacteria,1RPBT@1236|Gammaproteobacteria,1XUPF@135623|Vibrionales 135623|Vibrionales EGP of the major facilitator superfamily hcaT - - ko:K05820 - - - - ko00000,ko02000 2.A.1.27 - - MFS_1_like k141_6617_12 1116375.VEJY3_14600 0.0 2134.0 COG0591@1|root,COG0642@1|root,COG0784@1|root,COG0591@2|Bacteria,COG0784@2|Bacteria,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,1RP2U@1236|Gammaproteobacteria,1XUJN@135623|Vibrionales 135623|Vibrionales T COG0591 Na proline symporter - - - - - - - - - - - - HATPase_c,HisKA,PAS_7,Response_reg k141_6617_13 223926.28807899 2.16e-16 77.8 COG0114@1|root,COG0114@2|Bacteria,1MUQI@1224|Proteobacteria,1RNUS@1236|Gammaproteobacteria,1XVJG@135623|Vibrionales 135623|Vibrionales C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate fumC - 4.2.1.2 ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 M00009,M00011,M00173,M00376 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - - FumaraseC_C,Lyase_1 k141_24425_1 1034347.CAHJ01000068_gene2533 1.87e-36 127.0 COG2096@1|root,COG2096@2|Bacteria,1V3PI@1239|Firmicutes,4HH26@91061|Bacilli,1ZCJ1@1386|Bacillus 91061|Bacilli S Adenosyltransferase yvqK - 2.5.1.17 ko:K00798 ko00860,ko01100,map00860,map01100 M00122 R01492,R05220,R07268 RC00533 ko00000,ko00001,ko00002,ko01000 - - - Cob_adeno_trans k141_24425_2 218284.CCDN010000001_gene1378 9.49e-70 213.0 COG2087@1|root,COG2087@2|Bacteria,1VH9Y@1239|Firmicutes,4HNQX@91061|Bacilli,1ZJB9@1386|Bacillus 91061|Bacilli H Cobinamide kinase / cobinamide phosphate guanyltransferase - - - - - - - - - - - - CobU k141_24425_3 1211814.CAPG01000035_gene1776 5.53e-09 58.5 COG0406@1|root,COG0406@2|Bacteria,1V6G1@1239|Firmicutes,4HHCH@91061|Bacilli,1ZDMD@1386|Bacillus 91061|Bacilli G Histidine phosphatase superfamily (branch 1) cobC - 3.1.3.73 ko:K02226 ko00860,ko01100,map00860,map01100 M00122 R04594,R11173 RC00017 ko00000,ko00001,ko00002,ko01000 - - - His_Phos_1 k141_18604_1 1279017.AQYJ01000025_gene716 8.94e-60 188.0 2FGZH@1|root,348UM@2|Bacteria,1P152@1224|Proteobacteria,1SRIV@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_27043_1 1437824.BN940_01006 1.65e-31 113.0 COG1764@1|root,COG1764@2|Bacteria,1RD1A@1224|Proteobacteria,2VR4T@28216|Betaproteobacteria,3T3ZT@506|Alcaligenaceae 28216|Betaproteobacteria O Organic hydroperoxide resistance protein ohr - - - - - - - - - - - OsmC k141_27043_2 1453501.JELR01000002_gene1450 2.51e-66 206.0 COG1595@1|root,COG1595@2|Bacteria,1N2DR@1224|Proteobacteria,1S7D6@1236|Gammaproteobacteria,467MI@72275|Alteromonadaceae 1236|Gammaproteobacteria K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_37386_2 218284.CCDN010000005_gene3344 1.15e-199 557.0 COG1363@1|root,COG1363@2|Bacteria,1TQ86@1239|Firmicutes,4HBDK@91061|Bacilli,1ZBP8@1386|Bacillus 91061|Bacilli G peptidase M42 yhfE - - - - - - - - - - - Peptidase_M42 k141_2937_1 1121931.AUHG01000019_gene2987 2.19e-22 93.2 2CDPK@1|root,32RR8@2|Bacteria,4NSHW@976|Bacteroidetes,1I402@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - k141_2937_2 562973.HMPREF0059_01222 9.61e-24 91.7 COG1476@1|root,COG1476@2|Bacteria,2GQIU@201174|Actinobacteria,4D6A3@85005|Actinomycetales 201174|Actinobacteria K Helix-turn-helix domain - - - ko:K07729 - - - - ko00000,ko03000 - - - HTH_3 k141_2937_3 1042377.AFPJ01000035_gene2654 8.68e-233 651.0 COG0334@1|root,COG0334@2|Bacteria,1MUMF@1224|Proteobacteria,1RPUZ@1236|Gammaproteobacteria,4649P@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the Glu Leu Phe Val dehydrogenases family gdhA GO:0003674,GO:0003824,GO:0004353,GO:0004354,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.4 ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 - R00248 RC00006,RC02799 ko00000,ko00001,ko01000 - - iECH74115_1262.ECH74115_2481,iECSP_1301.ECSP_2329,iECs_1301.ECs2467,iG2583_1286.G2583_2207,iPC815.YPO3971,iSDY_1059.SDY_1514,iYL1228.KPN_01210,iZ_1308.Z2793 ELFV_dehydrog,ELFV_dehydrog_N k141_30214_1 218284.CCDN010000008_gene4225 4.44e-227 627.0 COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,4H9NG@91061|Bacilli,1ZCFZ@1386|Bacillus 91061|Bacilli K catabolite control protein A ccpA GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 k141_30214_2 218284.CCDN010000008_gene4226 6.22e-112 327.0 COG1291@1|root,COG1291@2|Bacteria,1TRH1@1239|Firmicutes,4HAXG@91061|Bacilli,1ZB8I@1386|Bacillus 91061|Bacilli N flagellar motor motP GO:0001539,GO:0005575,GO:0005623,GO:0005886,GO:0006928,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0040011,GO:0044425,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071944,GO:0071973,GO:0071978,GO:0097588 - ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - MotA_ExbB k141_6618_1 997296.PB1_09512 2.51e-84 261.0 COG0141@1|root,COG0141@2|Bacteria,1TPAW@1239|Firmicutes,4H9XK@91061|Bacilli,1ZCAX@1386|Bacillus 91061|Bacilli E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine hisD GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01158,R01163,R03012 RC00099,RC00242,RC00463 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU34910 Histidinol_dh k141_33960_1 1116375.VEJY3_13255 1.44e-138 394.0 COG1381@1|root,COG1381@2|Bacteria,1RHIC@1224|Proteobacteria,1RN8Y@1236|Gammaproteobacteria,1XU1R@135623|Vibrionales 135623|Vibrionales L Involved in DNA repair and RecF pathway recombination recO - - ko:K03584 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecO_C,RecO_N k141_33960_2 223926.28807579 4.71e-71 219.0 COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,1RMS5@1236|Gammaproteobacteria,1XTR0@135623|Vibrionales 135623|Vibrionales H Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate pdxJ GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 ko:K03474 ko00750,ko01100,map00750,map01100 M00124 R05838 RC01476 ko00000,ko00001,ko00002,ko01000 - - - PdxJ k141_5515_1 1380380.JIAX01000006_gene823 3.97e-24 105.0 COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,2TSGE@28211|Alphaproteobacteria 28211|Alphaproteobacteria U COG0457 FOG TPR repeat - - - - - - - - - - - - Sulfotransfer_3,TPR_1,TPR_10,TPR_11,TPR_12,TPR_16,TPR_2,TPR_6,TPR_8 k141_37387_1 1121013.P873_09715 5.06e-55 184.0 COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,1RNS1@1236|Gammaproteobacteria,1X349@135614|Xanthomonadales 135614|Xanthomonadales M Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxB GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 ko:K00748 ko00540,ko01100,map00540,map01100 M00060 R04606 RC00005,RC00059 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT19 - LpxB k141_35179_2 426117.M446_5059 2.86e-63 211.0 COG3486@1|root,COG3486@2|Bacteria,1MX36@1224|Proteobacteria,2U1RS@28211|Alphaproteobacteria,1JUBF@119045|Methylobacteriaceae 28211|Alphaproteobacteria Q L-lysine 6-monooxygenase (NADPH-requiring) vbsO - 1.14.13.195,1.14.13.196,1.14.13.59 ko:K03897,ko:K10531 ko00310,ko01120,map00310,map01120 - R00448 RC00298 ko00000,ko00001,ko01000 - - - K_oxygenase k141_32613_1 1116375.VEJY3_04470 1.45e-110 330.0 COG3014@1|root,COG3014@2|Bacteria,1PD4S@1224|Proteobacteria,1RQ8Y@1236|Gammaproteobacteria,1XUG4@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria - - - ko:K09859 - - - - ko00000 - - - - k141_10316_1 42565.FP66_01995 1.42e-93 281.0 COG1344@1|root,COG1344@2|Bacteria,1PJUJ@1224|Proteobacteria,1RPNR@1236|Gammaproteobacteria 1236|Gammaproteobacteria N Belongs to the bacterial flagellin family flgL GO:0005575,GO:0005576,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - ko:K02397 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flagellin_C,Flagellin_N k141_27045_1 218284.CCDN010000001_gene380 7.64e-115 340.0 COG4109@1|root,COG4109@2|Bacteria,1TPU6@1239|Firmicutes,4HB62@91061|Bacilli,1ZB1Q@1386|Bacillus 91061|Bacilli K transcriptional regulator containing CBS domains ytoI - - - - - - - - - - - 4HBT,CBS,DRTGG,GntR,HTH_24 k141_9038_1 42565.FP66_03330 1.97e-115 340.0 COG2270@1|root,COG2270@2|Bacteria,1QV57@1224|Proteobacteria,1T28V@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Major Facilitator - - - - - - - - - - - - Nuc_H_symport k141_6619_1 1453501.JELR01000001_gene3053 7.62e-52 171.0 COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,1RM7M@1236|Gammaproteobacteria,464CX@72275|Alteromonadaceae 1236|Gammaproteobacteria J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA rsmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 ko:K03438 - - - - ko00000,ko01000,ko03009 - - - Methyltransf_5 k141_6619_2 1453501.JELR01000001_gene3052 1.39e-39 133.0 COG3116@1|root,COG3116@2|Bacteria 2|Bacteria D cell division ftsL GO:0000003,GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0019954,GO:0022402,GO:0022414,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0043093,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944 - ko:K03586 - - - - ko00000,ko03036 - - - FtsL k141_11472_1 1279017.AQYJ01000029_gene3328 3.63e-79 255.0 COG0665@1|root,COG4121@1|root,COG0665@2|Bacteria,COG4121@2|Bacteria,1MZW5@1224|Proteobacteria,1RMTE@1236|Gammaproteobacteria,464VK@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 mnmC GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0004808,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016491,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363 2.1.1.61 ko:K15461 - - R00601,R08702 RC00003,RC00053,RC00060,RC01483 ko00000,ko01000,ko03016 - - - DAO,Methyltransf_30 k141_17269_21 768066.HELO_1906 2.53e-25 100.0 COG0662@1|root,COG1396@1|root,COG0662@2|Bacteria,COG1396@2|Bacteria,1RCYA@1224|Proteobacteria,1S4B9@1236|Gammaproteobacteria,1XJVH@135619|Oceanospirillales 135619|Oceanospirillales K XRE family transcriptional regulator - - - - - - - - - - - - Cupin_2,HTH_3 k141_25777_1 866895.HBHAL_3301 7.11e-10 60.5 COG5581@1|root,COG5581@2|Bacteria,1V31U@1239|Firmicutes,4HGFE@91061|Bacilli,3NF5Q@45667|Halobacillus 91061|Bacilli M Flagellar protein YcgR ypfA - - - - - - - - - - - PilZ,YcgR_2 k141_25777_3 218284.CCDN010000001_gene1092 9.36e-08 52.0 COG0283@1|root,COG0283@2|Bacteria,1V3IA@1239|Firmicutes,4HFZE@91061|Bacilli,1ZBXZ@1386|Bacillus 91061|Bacilli F Belongs to the cytidylate kinase family. Type 1 subfamily cmk GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 ko:K00945 ko00240,ko01100,map00240,map01100 M00052 R00158,R00512,R01665 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Cytidylate_kin k141_23387_2 218284.CCDN010000002_gene1998 2.02e-86 259.0 COG1646@1|root,COG1646@2|Bacteria,1TQQK@1239|Firmicutes,4H9YW@91061|Bacilli,1ZBBT@1386|Bacillus 91061|Bacilli I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales pcrB GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 - ko:K07094 - - - - ko00000,ko01000 - - - PcrB k141_16108_1 218284.CCDN010000006_gene3587 1.66e-36 125.0 2EJY1@1|root,30D5N@2|Bacteria,1UAVW@1239|Firmicutes,4IM8Q@91061|Bacilli,1ZJH3@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_11500_2 1131730.BAVI_15406 7.31e-40 133.0 2E9I0@1|root,333R2@2|Bacteria,1VG06@1239|Firmicutes,4HNXF@91061|Bacilli,1ZJ34@1386|Bacillus 91061|Bacilli S DNA alkylation repair protein - - - - - - - - - - - - - k141_11500_3 218284.CCDN010000001_gene1234 2.77e-77 239.0 COG0523@1|root,COG0523@2|Bacteria,1TPCG@1239|Firmicutes,4HFQ5@91061|Bacilli,1ZBXA@1386|Bacillus 91061|Bacilli S cobalamin synthesis protein P47K - - - - - - - - - - - - CobW_C,cobW k141_27091_1 237368.SCABRO_01882 2.8e-12 69.3 COG2304@1|root,COG2304@2|Bacteria,2IYWC@203682|Planctomycetes 203682|Planctomycetes S von Willebrand factor, type A - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - BatA,VWA,VWA_2 k141_27091_2 1121374.KB891576_gene492 1.25e-07 54.3 COG2304@1|root,COG2304@2|Bacteria,1MW51@1224|Proteobacteria,1RMD3@1236|Gammaproteobacteria 1236|Gammaproteobacteria K protein containing a von Willebrand factor type A (vWA) domain - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - TPR_1,TPR_2,VWA_2 k141_32650_1 218284.CCDN010000006_gene3738 2.27e-06 48.1 COG2011@1|root,COG2011@2|Bacteria,1TSJS@1239|Firmicutes,4HAZD@91061|Bacilli,1ZRMX@1386|Bacillus 91061|Bacilli P COG2011 ABC-type metal ion transport system, permease component metP_2 - - ko:K02072 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - BPD_transp_1 k141_32650_2 218284.CCDN010000006_gene3737 4.54e-93 277.0 COG1464@1|root,COG1464@2|Bacteria,1TRXS@1239|Firmicutes,4HAD4@91061|Bacilli,1ZBWI@1386|Bacillus 91061|Bacilli P COG1464 ABC-type metal ion transport system, periplasmic component surface antigen - - - ko:K02073 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - Lipoprotein_9 k141_30231_1 1042377.AFPJ01000014_gene1634 2.46e-185 519.0 COG2755@1|root,COG2755@2|Bacteria,1NAAJ@1224|Proteobacteria 1224|Proteobacteria E GDSL-like Lipase/Acylhydrolase - - - - - - - - - - - - Lipase_GDSL,Lipase_GDSL_2 k141_18644_1 218284.CCDN010000001_gene1379 2.48e-58 185.0 COG2096@1|root,COG2096@2|Bacteria,1V3PI@1239|Firmicutes,4HH26@91061|Bacilli,1ZCJ1@1386|Bacillus 91061|Bacilli S Adenosyltransferase yvqK - 2.5.1.17 ko:K00798 ko00860,ko01100,map00860,map01100 M00122 R01492,R05220,R07268 RC00533 ko00000,ko00001,ko00002,ko01000 - - - Cob_adeno_trans k141_18644_2 218284.CCDN010000001_gene1380 3.98e-09 55.1 2E87D@1|root,32STY@2|Bacteria,1VA96@1239|Firmicutes,4HKQA@91061|Bacilli,1ZGZS@1386|Bacillus 91061|Bacilli S ECF transporter, substrate-specific component - - - - - - - - - - - - ECF-ribofla_trS,ECF_trnsprt k141_24458_1 713586.KB900536_gene2107 1.4e-95 288.0 COG1656@1|root,COG1656@2|Bacteria,1R442@1224|Proteobacteria,1S4UH@1236|Gammaproteobacteria 1236|Gammaproteobacteria H Mut7-C RNAse domain - - - ko:K09122 - - - - ko00000 - - - Mut7-C,Ub-Mut7C k141_4233_1 223926.28807795 0.0 1025.0 COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,1RNVR@1236|Gammaproteobacteria,1XSSX@135623|Vibrionales 135623|Vibrionales P Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K( ) H( ) antiport kefB - - ko:K11747 - - - - ko00000,ko02000 2.A.37.1.2 - - Na_H_Exchanger,TrkA_N k141_4233_2 1116375.VEJY3_14225 6.72e-45 144.0 COG3529@1|root,COG3529@2|Bacteria,1N6RJ@1224|Proteobacteria,1SC9Y@1236|Gammaproteobacteria,1XZ08@135623|Vibrionales 135623|Vibrionales S nucleic-acid-binding protein containing a Zn-ribbon domain - - - ko:K07070 - - - - ko00000 - - - DUF2387 k141_4233_3 223926.28807793 3.36e-113 327.0 COG1047@1|root,COG1047@2|Bacteria,1RD35@1224|Proteobacteria,1S3QR@1236|Gammaproteobacteria,1XSRK@135623|Vibrionales 135623|Vibrionales G COG1047 FKBP-type peptidyl-prolyl cis-trans isomerases 2 slyD GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0006457,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0042026,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 ko:K03775 - - - - ko00000,ko01000,ko03110 - - - FKBP_C k141_4233_4 1116375.VEJY3_14215 2.03e-202 563.0 COG1446@1|root,COG1446@2|Bacteria,1MWFC@1224|Proteobacteria,1RNUR@1236|Gammaproteobacteria,1XU9Z@135623|Vibrionales 135623|Vibrionales E Enzyme with broad specificity iaaA - 3.4.19.5 ko:K13051 - - - - ko00000,ko01000,ko01002 - - - Asparaginase_2 k141_4233_5 1116375.VEJY3_14210 1.04e-43 142.0 COG2900@1|root,COG2900@2|Bacteria,1NGFM@1224|Proteobacteria,1SGAM@1236|Gammaproteobacteria,1XYDM@135623|Vibrionales 135623|Vibrionales S Belongs to the SlyX family slyX - - ko:K03745 - - - - ko00000 - - - SlyX k141_4233_6 1116375.VEJY3_14205 6.32e-163 464.0 COG2319@1|root,COG2319@2|Bacteria,1PDT0@1224|Proteobacteria,1RV85@1236|Gammaproteobacteria,1XTYR@135623|Vibrionales 135623|Vibrionales S COG2319 FOG WD40 repeat - - - - - - - - - - - - WD40 k141_4233_7 223926.28807788 5.54e-171 479.0 COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,1RRKU@1236|Gammaproteobacteria,1XSY6@135623|Vibrionales 135623|Vibrionales M COG0545 FKBP-type peptidyl-prolyl cis-trans isomerases 1 fkpA - 5.2.1.8 ko:K03772 - - - - ko00000,ko01000,ko03110 - - - FKBP_C,FKBP_N k141_4233_8 223926.28807787 1.43e-160 451.0 COG2964@1|root,COG2964@2|Bacteria,1MU5K@1224|Proteobacteria,1RPDQ@1236|Gammaproteobacteria,1XT3M@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria yheO - - - - - - - - - - - HTH_22,PAS_6 k141_4233_9 1116375.VEJY3_14190 8.95e-80 238.0 COG1553@1|root,COG1553@2|Bacteria,1N021@1224|Proteobacteria,1S99J@1236|Gammaproteobacteria,1XXDD@135623|Vibrionales 135623|Vibrionales P conserved protein involved in intracellular sulfur reduction tusD - - ko:K07235 ko04122,map04122 - - - ko00000,ko00001,ko01000,ko03016 - - - DrsE k141_4233_10 1116375.VEJY3_14185 7.45e-75 224.0 COG2923@1|root,COG2923@2|Bacteria,1N8RV@1224|Proteobacteria,1SD0S@1236|Gammaproteobacteria,1XXV7@135623|Vibrionales 135623|Vibrionales P Belongs to the DsrF TusC family tusC - - ko:K07236 ko04122,map04122 - - - ko00000,ko00001,ko03016 - - - DrsE k141_4233_11 674977.VMC_01460 1e-46 151.0 COG2168@1|root,COG2168@2|Bacteria,1NGF3@1224|Proteobacteria,1SGPI@1236|Gammaproteobacteria,1XYYQ@135623|Vibrionales 135623|Vibrionales P conserved protein involved in oxidation of intracellular sulfur tusB - - ko:K07237 ko04122,map04122 - - - ko00000,ko00001,ko03016 - - - DsrH k141_4233_12 1280001.BAOA01000039_gene2522 8.5e-86 252.0 COG0048@1|root,COG0048@2|Bacteria,1RCWY@1224|Proteobacteria,1S3WB@1236|Gammaproteobacteria,1XWXF@135623|Vibrionales 135623|Vibrionales J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit rpsL GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02950 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosom_S12_S23 k141_4233_13 1219076.N646_1866 6.36e-101 293.0 COG0049@1|root,COG0049@2|Bacteria,1MXC8@1224|Proteobacteria,1RN77@1236|Gammaproteobacteria,1XT47@135623|Vibrionales 135623|Vibrionales J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA rpsG GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02992 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S7 k141_4233_14 1116375.VEJY3_14165 0.0 1368.0 COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,1RNSZ@1236|Gammaproteobacteria,1XSMB@135623|Vibrionales 135623|Vibrionales J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome fusA1 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02355 - - - - ko00000,ko03012,ko03029 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 k141_4233_15 1116375.VEJY3_14800 2.09e-286 782.0 COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,1RMYX@1236|Gammaproteobacteria,1XSP1@135623|Vibrionales 135623|Vibrionales J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis tuf GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02358 - - - - ko00000,ko03012,ko03029,ko04147 - - - GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 k141_3132_1 1116375.VEJY3_11270 2.78e-230 639.0 COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,1RMB0@1236|Gammaproteobacteria,1XSGS@135623|Vibrionales 135623|Vibrionales H Belongs to the folylpolyglutamate synthase family folC - 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 - - - Mur_ligase_C,Mur_ligase_M k141_3132_2 1280001.BAOA01000009_gene4121 2.64e-78 240.0 COG0777@1|root,COG0777@2|Bacteria,1MW8G@1224|Proteobacteria,1RNDS@1236|Gammaproteobacteria,1XUF4@135623|Vibrionales 135623|Vibrionales I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA accD GO:0003674,GO:0003824,GO:0003989,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009317,GO:0009987,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0019752,GO:0032787,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576,GO:1902494 2.1.3.15,6.4.1.2 ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans k141_6863_2 1321815.HMPREF9193_00951 4.94e-31 110.0 COG0254@1|root,COG0254@2|Bacteria,2J93Z@203691|Spirochaetes 203691|Spirochaetes J 50S ribosomal protein L31 rpmE - - ko:K02909 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L31 k141_36316_1 218284.CCDN010000001_gene511 1.4e-79 243.0 COG0777@1|root,COG0777@2|Bacteria,1TP4U@1239|Firmicutes,4HAI7@91061|Bacilli,1ZB3M@1386|Bacillus 91061|Bacilli I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA accD - 2.1.3.15,6.4.1.2 ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans k141_15037_2 1042377.AFPJ01000037_gene2944 9.59e-21 90.9 COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,1RNAZ@1236|Gammaproteobacteria,464M5@72275|Alteromonadaceae 1236|Gammaproteobacteria L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseA GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494 3.1.11.6 ko:K03601 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_L,tRNA_anti_2 k141_37523_1 1294265.JCM21738_2248 7.19e-94 287.0 COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,4H9RY@91061|Bacilli,1ZBR9@1386|Bacillus 91061|Bacilli S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid ytgP GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03328 - - - - ko00000 2.A.66.2 - - Polysacc_synt,Polysacc_synt_C k141_14192_1 1131730.BAVI_14761 9.35e-77 236.0 COG0789@1|root,COG0789@2|Bacteria,1TS6Z@1239|Firmicutes,4HCVW@91061|Bacilli,1ZBMT@1386|Bacillus 91061|Bacilli K transcriptional mta - - - - - - - - - - - MerR_1,TipAS k141_35385_1 240015.ACP_1022 1.14e-20 87.4 COG0346@1|root,COG0346@2|Bacteria,3Y5PU@57723|Acidobacteria,2JN0W@204432|Acidobacteriia 204432|Acidobacteriia E Glyoxalase-like domain - - - - - - - - - - - - Glyoxalase_4 k141_35385_2 3218.PP1S274_79V6.1 2.72e-19 83.6 COG0526@1|root,KOG0910@2759|Eukaryota,37V9V@33090|Viridiplantae,3GIVR@35493|Streptophyta 35493|Streptophyta O Thioredoxin X - GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008047,GO:0008150,GO:0008152,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0030234,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043085,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044093,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0065009,GO:0070887,GO:0097237,GO:0098754,GO:0098772,GO:0098869,GO:1990748 - ko:K03671 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - Thioredoxin k141_4348_2 997296.PB1_09887 4.91e-16 75.1 COG0396@1|root,COG0396@2|Bacteria,1TQ98@1239|Firmicutes,4HAD9@91061|Bacilli,1ZAW4@1386|Bacillus 91061|Bacilli O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component sufC - - ko:K09013 - - - - ko00000,ko02000 - - - ABC_tran k141_23622_1 1279017.AQYJ01000023_gene3274 4.16e-306 846.0 COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,1RP55@1236|Gammaproteobacteria,465RX@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1178 ABC-type Fe3 transport system, permease component - - - ko:K02011 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - BPD_transp_1 k141_6864_1 1453501.JELR01000002_gene1341 3.69e-152 434.0 COG2067@1|root,COG2067@2|Bacteria,1PXPC@1224|Proteobacteria,1RQKS@1236|Gammaproteobacteria,46D8K@72275|Alteromonadaceae 1236|Gammaproteobacteria I Protein of unknown function (DUF3570) - - - - - - - - - - - - DUF3570 k141_30332_1 1294265.JCM21738_2258 4.85e-97 285.0 COG1514@1|root,COG1514@2|Bacteria,1VCBK@1239|Firmicutes,4HM3V@91061|Bacilli,1ZHT8@1386|Bacillus 91061|Bacilli J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester ytlP GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 ko:K01975 - - - - ko00000,ko01000,ko03016 - - - LigT_PEase k141_30332_2 1196031.ALEG01000064_gene3530 2.86e-10 59.7 28NSI@1|root,2ZB4U@2|Bacteria,1UZ00@1239|Firmicutes,4HDBT@91061|Bacilli,1ZDNP@1386|Bacillus 91061|Bacilli - - ytlQ - - - - - - - - - - - NERD k141_14193_1 218284.CCDN010000002_gene2106 3.5e-54 180.0 COG1071@1|root,COG1071@2|Bacteria,1TQDG@1239|Firmicutes,4H9PR@91061|Bacilli,1ZARF@1386|Bacillus 91061|Bacilli C Dehydrogenase E1 component - - 1.2.4.1 ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh k141_933_1 1294265.JCM21738_3798 1.22e-165 470.0 COG1721@1|root,COG1721@2|Bacteria,1TUWF@1239|Firmicutes,4HDRE@91061|Bacilli,1ZCAS@1386|Bacillus 91061|Bacilli S conserved protein (some members contain a von Willebrand factor type A (vWA) domain) yeaD - - - - - - - - - - - DUF58 k141_3133_1 1122134.KB893650_gene1755 3.93e-13 63.9 2DR5Z@1|root,33ABB@2|Bacteria,1NIYJ@1224|Proteobacteria,1SGQ9@1236|Gammaproteobacteria,1XQB9@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_27946_1 1294265.JCM21738_2902 3.09e-261 723.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,1ZBIW@1386|Bacillus 91061|Bacilli V COG1132 ABC-type multidrug transport system, ATPase and permease components yheH GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702 - ko:K18217,ko:K18890 ko02010,map02010 M00635,M00707 - - ko00000,ko00001,ko00002,ko01504,ko02000 3.A.1,3.A.1.106.13,3.A.1.106.5 - - ABC_membrane,ABC_tran k141_37524_1 218284.CCDN010000001_gene1648 2.29e-112 338.0 COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4H9ZK@91061|Bacilli,1ZCFC@1386|Bacillus 91061|Bacilli S ABC transporter - - - - - - - - - - - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn k141_7927_1 1280001.BAOA01000126_gene1157 2.72e-23 94.7 COG1018@1|root,COG1018@2|Bacteria,1MW37@1224|Proteobacteria,1RR95@1236|Gammaproteobacteria,1XVIM@135623|Vibrionales 135623|Vibrionales C COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 fpr - 1.18.1.2,1.19.1.1 ko:K00528 - - R10159 - ko00000,ko01000 - - - FAD_binding_6,NAD_binding_1 k141_7927_2 1116375.VEJY3_23631 2.58e-100 291.0 COG0824@1|root,COG0824@2|Bacteria,1RHCN@1224|Proteobacteria,1S4PS@1236|Gammaproteobacteria,1XXBU@135623|Vibrionales 135623|Vibrionales S Thioesterase-like superfamily - - - ko:K07107 - - - - ko00000,ko01000 - - - 4HBT_2 k141_7927_3 223926.28809990 8.33e-47 150.0 COG4628@1|root,COG4628@2|Bacteria,1N7DG@1224|Proteobacteria,1SCBE@1236|Gammaproteobacteria,1XYE5@135623|Vibrionales 135623|Vibrionales S DNA-binding protein VF530 - GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0097159,GO:1901363 - - - - - - - - - - VF530 k141_29298_1 1116375.VEJY3_02270 3.79e-22 94.0 COG1115@1|root,COG1115@2|Bacteria,1MUI3@1224|Proteobacteria,1RMNF@1236|Gammaproteobacteria,1XTS9@135623|Vibrionales 135623|Vibrionales U alanine symporter yaaJ - - ko:K03310 - - - - ko00000 2.A.25 - - Na_Ala_symp k141_29298_2 223926.28805487 7.98e-177 493.0 COG3022@1|root,COG3022@2|Bacteria,1MUAF@1224|Proteobacteria,1RMTD@1236|Gammaproteobacteria,1XUFU@135623|Vibrionales 135623|Vibrionales S Belongs to the UPF0246 family yaaA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0033194,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:1901700 - ko:K09861 - - - - ko00000 - - - H2O2_YaaD k141_29298_3 674977.VMC_01850 2.93e-262 722.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1XSEA@135623|Vibrionales 135623|Vibrionales F DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity srmB - 3.6.4.13 ko:K05590 - - - - ko00000,ko01000,ko03009 - - - DEAD,Helicase_C k141_29298_4 1116375.VEJY3_02285 2.87e-140 399.0 COG4123@1|root,COG4123@2|Bacteria,1PC8R@1224|Proteobacteria,1RM8S@1236|Gammaproteobacteria,1XTHE@135623|Vibrionales 135623|Vibrionales J Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) yfiC GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016426,GO:0016430,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.223 ko:K15460 - - - - ko00000,ko01000,ko03016 - - - MTS k141_29298_5 1219076.N646_2660 9.18e-278 765.0 COG1114@1|root,COG1114@2|Bacteria,1MVIF@1224|Proteobacteria,1RR3P@1236|Gammaproteobacteria,1XTP0@135623|Vibrionales 135623|Vibrionales U Component of the transport system for branched-chain amino acids brnQ - - ko:K03311 - - - - ko00000 2.A.26 - - Branch_AA_trans k141_29298_6 1280001.BAOA01000120_gene224 3.88e-121 345.0 COG0716@1|root,COG0716@2|Bacteria,1QRBW@1224|Proteobacteria,1RMED@1236|Gammaproteobacteria,1XSJG@135623|Vibrionales 135623|Vibrionales C Low-potential electron donor to a number of redox enzymes fldB - - ko:K03840 - - - - ko00000 - - - Flavodoxin_1 k141_29298_7 1116375.VEJY3_02300 2.25e-211 585.0 COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,1RPI8@1236|Gammaproteobacteria,1XT87@135623|Vibrionales 135623|Vibrionales D recombinase XerD xerD GO:0000150,GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009009,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140097,GO:1901360 - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase k141_29298_8 1116375.VEJY3_02305 3.07e-169 474.0 COG1651@1|root,COG1651@2|Bacteria,1RD39@1224|Proteobacteria,1S3U8@1236|Gammaproteobacteria,1XSD4@135623|Vibrionales 135623|Vibrionales O Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process dsbC - 5.3.4.1 ko:K03981 - - - - ko00000,ko01000,ko02044,ko03110 3.A.7.11.1 - - DsbC_N,Thioredoxin_2 k141_29298_9 1116375.VEJY3_02310 0.0 1112.0 COG0608@1|root,COG0608@2|Bacteria,1MU1M@1224|Proteobacteria,1RMF4@1236|Gammaproteobacteria,1XTR9@135623|Vibrionales 135623|Vibrionales L exonuclease recj recJ - - ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1 k141_29298_10 674977.VMC_01920 1.5e-181 506.0 COG1186@1|root,COG1186@2|Bacteria,1MUAW@1224|Proteobacteria,1RP9Z@1236|Gammaproteobacteria,1XSN5@135623|Vibrionales 135623|Vibrionales J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA prfB - - ko:K02836 - - - - ko00000,ko03012 - - - PCRF,RF-1 k141_29298_11 1116375.VEJY3_02320 0.0 983.0 COG1190@1|root,COG1190@2|Bacteria,1MX1V@1224|Proteobacteria,1RMJN@1236|Gammaproteobacteria,1XSNE@135623|Vibrionales 135623|Vibrionales J Belongs to the class-II aminoacyl-tRNA synthetase family lysS GO:0003674,GO:0003824,GO:0004812,GO:0004824,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006430,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.6 ko:K04567 ko00970,map00970 M00359,M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2,tRNA_anti-codon k141_29298_12 223926.28805497 1.03e-300 822.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1XUBG@135623|Vibrionales 135623|Vibrionales K COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - ko:K20919 ko05111,map05111 - - - ko00000,ko00001,ko03000 - - - HTH_8,Sigma54_activat k141_29298_14 1116375.VEJY3_02330 2.4e-48 154.0 2EG26@1|root,339U6@2|Bacteria,1NJKH@1224|Proteobacteria,1SJG2@1236|Gammaproteobacteria,1XYAQ@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_29298_15 1116375.VEJY3_02335 7.35e-248 680.0 COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,1RNXH@1236|Gammaproteobacteria,1XTZ8@135623|Vibrionales 135623|Vibrionales C oxidoreductases (related to aryl-alcohol dehydrogenases) tas - - - - - - - - - - - Aldo_ket_red k141_29298_16 1280001.BAOA01000120_gene214 1.49e-67 204.0 2AWC6@1|root,31N7Z@2|Bacteria,1QJZC@1224|Proteobacteria,1TI1T@1236|Gammaproteobacteria,1XY6C@135623|Vibrionales 135623|Vibrionales - - VP0517 - - - - - - - - - - - - k141_29298_17 1116375.VEJY3_02345 2.13e-156 439.0 COG3066@1|root,COG3066@2|Bacteria,1MVYX@1224|Proteobacteria,1RQVV@1236|Gammaproteobacteria,1XV3G@135623|Vibrionales 135623|Vibrionales L Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair mutH GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - ko:K03573 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutH k141_29298_18 1219076.N646_2673 1.16e-127 362.0 COG0494@1|root,COG0494@2|Bacteria,1RDGJ@1224|Proteobacteria,1S3PQ@1236|Gammaproteobacteria,1XUD3@135623|Vibrionales 135623|Vibrionales L Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage nudH GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019222,GO:0019439,GO:0033554,GO:0034353,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 - ko:K08311 ko03018,map03018 - R10816 RC00002 ko00000,ko00001,ko01000,ko03019 - - - NUDIX k141_29298_19 1116375.VEJY3_02355 0.0 1407.0 COG3605@1|root,COG3605@2|Bacteria,1QTTV@1224|Proteobacteria,1T1H2@1236|Gammaproteobacteria,1XSXI@135623|Vibrionales 135623|Vibrionales T Belongs to the PEP-utilizing enzyme family ptsP - 2.7.3.9 ko:K08484 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 - - - GAF,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C k141_29298_20 1116375.VEJY3_02360 6.93e-153 433.0 COG0730@1|root,COG0730@2|Bacteria,1R3V4@1224|Proteobacteria,1RVNC@1236|Gammaproteobacteria,1XUH0@135623|Vibrionales 135623|Vibrionales S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE k141_29298_21 1219076.N646_2676 2.01e-207 572.0 COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,1RMVK@1236|Gammaproteobacteria,1XSP4@135623|Vibrionales 135623|Vibrionales M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins lgt GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 - ko:K13292 - - - - ko00000,ko01000 - - - LGT k141_29298_22 1116375.VEJY3_02370 1.22e-213 588.0 COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria,1RPYV@1236|Gammaproteobacteria,1XUA4@135623|Vibrionales 135623|Vibrionales F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis thyA GO:0003674,GO:0003824,GO:0004799,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0032259,GO:0034641,GO:0034654,GO:0042083,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046385,GO:0046483,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 - - - Thymidylat_synt k141_29298_23 223926.28805508 4.23e-239 661.0 COG3930@1|root,COG3930@2|Bacteria,1PYFH@1224|Proteobacteria,1RP1J@1236|Gammaproteobacteria,1XV5B@135623|Vibrionales 135623|Vibrionales S DUF1704 - - - - - - - - - - - - DUF1704 k141_29298_24 1219076.N646_2679 1.71e-247 682.0 COG1283@1|root,COG1283@2|Bacteria,1MXWU@1224|Proteobacteria,1RP6R@1236|Gammaproteobacteria,1XUP0@135623|Vibrionales 135623|Vibrionales P COG1283 Na phosphate symporter nptA - - ko:K14683 - - - - ko00000,ko02000,ko04147 2.A.58.1 - - Na_Pi_cotrans k141_29298_25 1116375.VEJY3_02385 1.78e-208 577.0 COG0583@1|root,COG0583@2|Bacteria,1MVHT@1224|Proteobacteria,1RN7G@1236|Gammaproteobacteria,1XT8V@135623|Vibrionales 135623|Vibrionales K Transcriptional activator nhaR GO:0003674,GO:0003700,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 - ko:K03717 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate k141_20934_2 218284.CCDN010000001_gene583 1.32e-82 246.0 COG1846@1|root,COG1846@2|Bacteria,1VACT@1239|Firmicutes,4HHUZ@91061|Bacilli,1ZG8C@1386|Bacillus 91061|Bacilli K transcriptional ysmB - - - - - - - - - - - MarR k141_20934_3 1499685.CCFJ01000046_gene3266 2.34e-40 134.0 COG2197@1|root,COG2197@2|Bacteria,1VBZR@1239|Firmicutes,4HKT4@91061|Bacilli,1ZHTA@1386|Bacillus 91061|Bacilli K Transcriptional regulator gerE - - ko:K01994 - - - - ko00000,ko03000 - - - GerE k141_6900_1 935837.JAEK01000034_gene3028 1.06e-42 145.0 COG0454@1|root,COG0456@2|Bacteria,1U521@1239|Firmicutes,4HBEJ@91061|Bacilli,1ZCHR@1386|Bacillus 91061|Bacilli K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases ykwB - - - - - - - - - - - Acetyltransf_1 k141_23657_1 62928.azo1344 3.37e-48 167.0 COG2010@1|root,COG2010@2|Bacteria,1MUCW@1224|Proteobacteria,2VHGS@28216|Betaproteobacteria,2KUZH@206389|Rhodocyclales 206389|Rhodocyclales C C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex ccoP - - ko:K00406 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002 3.D.4.3 - - Cytochrome_CBB3,FixP_N k141_34152_1 1453501.JELR01000001_gene3245 4.01e-135 394.0 2ASXF@1|root,31ID0@2|Bacteria,1RM30@1224|Proteobacteria,1S8I2@1236|Gammaproteobacteria,46BFQ@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_14231_1 42565.FP66_00840 1.17e-109 346.0 COG1330@1|root,COG1330@2|Bacteria,1MWTI@1224|Proteobacteria,1RNT0@1236|Gammaproteobacteria,1XHMF@135619|Oceanospirillales 135619|Oceanospirillales L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity recC - 3.1.11.5 ko:K03583 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_V_gamma k141_37549_1 1294265.JCM21738_2272 2.27e-53 170.0 2DMXQ@1|root,32UHX@2|Bacteria,1VD2A@1239|Firmicutes,4HKUA@91061|Bacilli,1ZJEN@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_9316_1 1121335.Clst_2359 4.76e-61 201.0 COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,248UI@186801|Clostridia,3WIAE@541000|Ruminococcaceae 186801|Clostridia L PFAM Transposase, Mutator - - - - - - - - - - - - Transposase_mut k141_29338_1 309799.DICTH_1451 3.83e-64 218.0 COG0466@1|root,COG0466@2|Bacteria 2|Bacteria O ATP-dependent peptidase activity lon - 3.4.21.53 ko:K01338 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - AAA,LON_substr_bdg,Lon_C k141_27972_2 1042377.AFPJ01000019_gene2504 1.72e-39 144.0 COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,1RN13@1236|Gammaproteobacteria,465K9@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine mtaD - 3.5.4.28,3.5.4.31 ko:K12960 ko00270,ko01100,map00270,map01100 - R09660 RC00477 ko00000,ko00001,ko01000 - - - Amidohydro_1 k141_6901_1 1294265.JCM21738_1350 2.96e-117 346.0 COG2056@1|root,COG2056@2|Bacteria,1TSRY@1239|Firmicutes,4HBK6@91061|Bacilli,1ZB9I@1386|Bacillus 91061|Bacilli S antiporter yuiF - - ko:K07084 - - - - ko00000,ko02000 2.A.8.1.12 - iSB619.SA_RS04585 Na_H_antiport_2,Na_H_antiporter k141_18935_1 218284.CCDN010000008_gene4189 1.5e-115 344.0 COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,4H9RY@91061|Bacilli,1ZBR9@1386|Bacillus 91061|Bacilli S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid ytgP GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03328 - - - - ko00000 2.A.66.2 - - Polysacc_synt,Polysacc_synt_C k141_23658_1 861299.J421_4119 1.04e-14 72.8 COG0534@1|root,COG0534@2|Bacteria,1ZT8D@142182|Gemmatimonadetes 142182|Gemmatimonadetes V MatE - - - - - - - - - - - - MatE k141_23658_2 1033802.SSPSH_000801 5.61e-14 68.6 COG2924@1|root,COG2924@2|Bacteria,1MZ2V@1224|Proteobacteria,1S964@1236|Gammaproteobacteria 1236|Gammaproteobacteria CO Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes yggX GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0033554,GO:0034599,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0070887 - - - - - - - - - - Iron_traffic k141_1889_2 1279017.AQYJ01000019_gene1482 4.73e-177 505.0 COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,1RN70@1236|Gammaproteobacteria,464FE@72275|Alteromonadaceae 1236|Gammaproteobacteria EGP COG0477 Permeases of the major facilitator superfamily yajR GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - - - - - - - - - - MFS_1,Sugar_tr k141_1889_3 1453501.JELR01000005_gene1754 2.69e-87 261.0 COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,1S3WP@1236|Gammaproteobacteria,466WC@72275|Alteromonadaceae 1236|Gammaproteobacteria L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k141_1889_4 1279017.AQYJ01000019_gene1484 7.97e-104 310.0 COG1091@1|root,COG1091@2|Bacteria,1MUXM@1224|Proteobacteria,1S1MF@1236|Gammaproteobacteria,468FS@72275|Alteromonadaceae 1236|Gammaproteobacteria M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose - - 1.1.1.133 ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777 RC00182 ko00000,ko00001,ko00002,ko01000 - - - RmlD_sub_bind k141_9317_1 358681.BBR47_00210 3.66e-36 133.0 COG1840@1|root,COG1840@2|Bacteria,1TR2S@1239|Firmicutes,4HC4U@91061|Bacilli,26RY4@186822|Paenibacillaceae 91061|Bacilli P ABC transporter substrate-binding protein - - - ko:K02055 ko02024,map02024 M00193 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11 - - SBP_bac_6 k141_27342_2 218284.CCDN010000002_gene2844 5.25e-67 203.0 COG1440@1|root,COG1440@2|Bacteria,1VA8X@1239|Firmicutes,4HKFF@91061|Bacilli,1ZHIA@1386|Bacillus 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIB subunit - - 2.7.1.196,2.7.1.205 ko:K02760 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 - - PTS_IIB k141_27342_3 997346.HMPREF9374_3317 7.41e-13 67.4 COG1455@1|root,COG1455@2|Bacteria,1TP8D@1239|Firmicutes,4H9W2@91061|Bacilli,27AWQ@186824|Thermoactinomycetaceae 91061|Bacilli G Phosphotransferase system, EIIC - - - ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 - - PTS_EIIC k141_25957_1 1380354.JIAN01000005_gene2040 5.67e-15 78.2 COG1266@1|root,COG1266@2|Bacteria,2GMJ1@201174|Actinobacteria 201174|Actinobacteria S PFAM Abortive infection protein - - - ko:K07052 - - - - ko00000 - - - Abi k141_10431_1 1294265.JCM21738_2413 9.92e-110 318.0 COG0614@1|root,COG0614@2|Bacteria,1UNE3@1239|Firmicutes,4H9ZX@91061|Bacilli,1ZBS8@1386|Bacillus 91061|Bacilli P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component yvrC - - ko:K02016 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - Peripla_BP_2 k141_35418_1 1279017.AQYJ01000026_gene111 5.91e-81 260.0 COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,1SYC8@1236|Gammaproteobacteria,46AMB@72275|Alteromonadaceae 1236|Gammaproteobacteria P Sulfate permease family - - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - STAS,Sulfate_transp k141_35418_2 1279017.AQYJ01000026_gene110 2.9e-58 184.0 COG2391@1|root,COG2391@2|Bacteria,1MZC0@1224|Proteobacteria,1S8UB@1236|Gammaproteobacteria,467VW@72275|Alteromonadaceae 1236|Gammaproteobacteria S Transporter component - - - ko:K07112 - - - - ko00000 - - - Sulf_transp k141_35418_4 1279017.AQYJ01000026_gene108 2.26e-49 159.0 COG0640@1|root,COG0640@2|Bacteria,1N72Q@1224|Proteobacteria,1SCH5@1236|Gammaproteobacteria,468EB@72275|Alteromonadaceae 1236|Gammaproteobacteria K transcriptional bigR GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - - - - - - - - - - HTH_5 k141_35418_5 1453501.JELR01000001_gene2600 5.5e-185 517.0 COG0491@1|root,COG0491@2|Bacteria,1MURA@1224|Proteobacteria,1RN27@1236|Gammaproteobacteria,464NE@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0491 Zn-dependent hydrolases, including glyoxylases blh - - - - - - - - - - - Lactamase_B k141_29339_1 218284.CCDN010000001_gene1390 5.35e-186 523.0 COG1092@1|root,COG1092@2|Bacteria,1TRAJ@1239|Firmicutes,4HAA1@91061|Bacilli,1ZBVG@1386|Bacillus 91061|Bacilli J Methyltransferase ywbD - 2.1.1.191 ko:K06969 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_SAM k141_18936_1 1453501.JELR01000002_gene825 2.83e-154 468.0 COG3866@1|root,COG3866@2|Bacteria,1QPFF@1224|Proteobacteria,1RQEM@1236|Gammaproteobacteria,465CX@72275|Alteromonadaceae 1236|Gammaproteobacteria G Amb_all pel1C - - - - - - - - - - - CBM_35,CBM_5_12_2,CBM_6,Pec_lyase_C,RicinB_lectin_2 k141_29340_1 236097.ADG881_1347 1.9e-39 144.0 COG4642@1|root,COG4642@2|Bacteria,1P07C@1224|Proteobacteria,1S26V@1236|Gammaproteobacteria,1XKUT@135619|Oceanospirillales 135619|Oceanospirillales S protein conserved in bacteria - - - - - - - - - - - - MORN,Peptidase_C13 k141_35419_1 1294265.JCM21738_1438 6.04e-12 62.8 COG0477@1|root,COG2814@2|Bacteria,1UY8I@1239|Firmicutes,4HDBH@91061|Bacilli,1ZEBN@1386|Bacillus 91061|Bacilli EGP COG0477 Permeases of the major facilitator superfamily - - - - - - - - - - - - MFS_1,MFS_3 k141_35419_2 1294265.JCM21738_1439 1.6e-68 214.0 COG0388@1|root,COG0388@2|Bacteria,1TQAZ@1239|Firmicutes,4HCQW@91061|Bacilli,1ZB16@1386|Bacillus 91061|Bacilli K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - - - - - - - - - - CN_hydrolase k141_37551_1 1189612.A33Q_2982 0.000723 46.6 COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,47U4M@768503|Cytophagia 976|Bacteroidetes G Sortilin, neurotensin receptor 3, - - - - - - - - - - - - Sortilin-Vps10 k141_23661_1 1545702.LACWKB8_0073 0.000398 48.5 COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,4HFJ8@91061|Bacilli,3FC5I@33958|Lactobacillaceae 91061|Bacilli K helix_turn _helix lactose operon repressor - - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 k141_22312_1 218284.CCDN010000001_gene555 3.87e-268 745.0 COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,1TQ33@1239|Firmicutes,4HAI2@91061|Bacilli,1ZB3A@1386|Bacillus 91061|Bacilli L COG1796 DNA polymerase IV (family X) polX - - ko:K02347 - - - - ko00000,ko03400 - - - DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8,PHP k141_22312_2 218284.CCDN010000001_gene556 1.55e-197 569.0 COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,4H9NZ@91061|Bacilli,1ZBJV@1386|Bacillus 91061|Bacilli L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity mutS2 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K07456 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_V,Smr k141_25959_1 1453501.JELR01000002_gene934 2.59e-123 352.0 COG1949@1|root,COG1949@2|Bacteria,1R9WX@1224|Proteobacteria,1S217@1236|Gammaproteobacteria,466JQ@72275|Alteromonadaceae 1236|Gammaproteobacteria A 3'-to-5' exoribonuclease specific for small oligoribonucleotides orn GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004532,GO:0004536,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0008946,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0016896,GO:0019439,GO:0034611,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140097,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - ko:K13288 ko03008,map03008 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - RNase_T k141_19921_1 316275.VSAL_I0707 6.44e-26 98.2 COG1447@1|root,COG1447@2|Bacteria,1N0T8@1224|Proteobacteria,1S9TV@1236|Gammaproteobacteria,1Y2MN@135623|Vibrionales 135623|Vibrionales H PTS system, Lactose/Cellobiose specific IIA subunit - - 2.7.1.196,2.7.1.205 ko:K02759 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 - - PTS_IIA k141_19921_2 55207.KP22_20595 2.44e-38 130.0 COG1440@1|root,COG1440@2|Bacteria,1MZHX@1224|Proteobacteria,1S94Q@1236|Gammaproteobacteria,1MSTY@122277|Pectobacterium 1236|Gammaproteobacteria G PTS system, Lactose/Cellobiose specific IIB subunit bglE - 2.7.1.196,2.7.1.205 ko:K02760 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 - - PTS_IIB k141_19921_4 561229.Dd1591_1052 5.56e-158 450.0 COG0657@1|root,COG0657@2|Bacteria,1R4AU@1224|Proteobacteria,1RQMN@1236|Gammaproteobacteria,2JCRB@204037|Dickeya 1236|Gammaproteobacteria I PFAM Alpha beta hydrolase fold-3 domain protein - - - - - - - - - - - - Abhydrolase_3,Peptidase_S9 k141_18937_1 218284.CCDN010000001_gene1867 9.02e-97 295.0 COG3845@1|root,COG3845@2|Bacteria,1UYQA@1239|Firmicutes,4HVSH@91061|Bacilli,1ZS12@1386|Bacillus 91061|Bacilli S ABC transporter, ATP-binding protein yufO - 3.6.3.17 ko:K02056 - M00221 - - ko00000,ko00002,ko01000,ko02000 3.A.1.2 - - ABC_tran k141_23662_1 1042377.AFPJ01000032_gene2688 9.58e-13 69.3 COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,1RM7S@1236|Gammaproteobacteria,4640S@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0739 Membrane proteins related to metalloendopeptidases yebA - - - - - - - - - - - OapA,OapA_N,Peptidase_M23 k141_30467_2 1280001.BAOA01000081_gene3027 1.47e-24 93.6 2AWNI@1|root,31NJB@2|Bacteria,1QKA0@1224|Proteobacteria,1TIDI@1236|Gammaproteobacteria,1XYXM@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF2897) - - - - - - - - - - - - DUF2897 k141_16465_1 218284.CCDN010000001_gene1520 1.58e-157 444.0 COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,4H9S9@91061|Bacilli,1ZCVZ@1386|Bacillus 91061|Bacilli E Methionine aminopeptidase map_1 - 3.4.11.18 ko:K01265 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M24 k141_3308_1 1294265.JCM21738_2681 2.5e-136 389.0 COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HB3V@91061|Bacilli,1ZB8V@1386|Bacillus 91061|Bacilli IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - ko:K00666 - - - - ko00000,ko01000,ko01004 - - - AMP-binding,AMP-binding_C k141_1166_1 589865.DaAHT2_1949 2.88e-18 84.0 COG4275@1|root,COG4275@2|Bacteria,1MYDE@1224|Proteobacteria,437XY@68525|delta/epsilon subdivisions,2X9RP@28221|Deltaproteobacteria,2MPAD@213118|Desulfobacterales 28221|Deltaproteobacteria S Chromate resistance exported protein - - - - - - - - - - - - Chrome_Resist k141_1166_2 1411123.JQNH01000001_gene3823 3.26e-34 128.0 COG2059@1|root,COG2059@2|Bacteria,1MUBW@1224|Proteobacteria,2TRXF@28211|Alphaproteobacteria 28211|Alphaproteobacteria P TIGRFAM chromate transporter, chromate ion transporter (CHR) family MA20_36630 - - ko:K07240 - - - - ko00000,ko02000 2.A.51.1 - - Chromate_transp k141_17561_1 42565.FP66_01165 4.04e-38 129.0 2EMNU@1|root,33FB8@2|Bacteria,1NNXU@1224|Proteobacteria,1SJAS@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_10541_1 1278073.MYSTI_00047 3.39e-56 188.0 COG3386@1|root,COG3386@2|Bacteria,1NIN4@1224|Proteobacteria 1224|Proteobacteria G Major royal jelly protein - - - - - - - - - - - - MRJP k141_24847_1 218284.CCDN010000005_gene3438 1.76e-122 360.0 COG2056@1|root,COG2056@2|Bacteria,1TSRY@1239|Firmicutes,4HBK6@91061|Bacilli,1ZB9I@1386|Bacillus 91061|Bacilli S antiporter yuiF - - ko:K07084 - - - - ko00000,ko02000 2.A.8.1.12 - iSB619.SA_RS04585 Na_H_antiport_2,Na_H_antiporter k141_4533_1 1307436.PBF_22687 3.32e-156 452.0 COG1694@1|root,COG3956@2|Bacteria,1TPK1@1239|Firmicutes,4HA0A@91061|Bacilli,1ZAYB@1386|Bacillus 91061|Bacilli S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like yabN GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.66 ko:K02428,ko:K02499 ko00230,map00230 - R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000,ko03036 - - - MazG,TP_methylase k141_29555_1 1453501.JELR01000005_gene1644 5.4e-87 257.0 COG2050@1|root,COG2050@2|Bacteria,1RGVP@1224|Proteobacteria,1S5WY@1236|Gammaproteobacteria,468JY@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Thioesterase superfamily menI GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0061522,GO:0071704,GO:1901576,GO:1901661,GO:1901663 3.1.2.28 ko:K19222 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R07262 RC00004,RC00174 ko00000,ko00001,ko00002,ko01000 - - - 4HBT k141_29555_2 1453501.JELR01000005_gene1645 1.69e-79 241.0 COG1451@1|root,COG1451@2|Bacteria,1MXZU@1224|Proteobacteria,1S9E4@1236|Gammaproteobacteria,467T2@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function DUF45 - - - ko:K07043 - - - - ko00000 - - - DUF45 k141_20142_1 1042377.AFPJ01000008_gene2017 1.58e-78 240.0 COG1028@1|root,COG1028@2|Bacteria,1MVQW@1224|Proteobacteria,1RNY1@1236|Gammaproteobacteria,46A35@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ KR domain - - 1.1.1.304,1.1.1.76 ko:K03366 ko00650,map00650 - R02855,R02946,R03707,R09078,R10505 RC00205,RC00525 ko00000,ko00001,ko01000 - - - adh_short_C2 k141_20142_2 1042377.AFPJ01000008_gene2016 1.13e-53 169.0 2EBHU@1|root,335I9@2|Bacteria,1N2MU@1224|Proteobacteria,1S9MV@1236|Gammaproteobacteria,46BQV@72275|Alteromonadaceae 1236|Gammaproteobacteria S REDY-like protein HapK - - - - - - - - - - - - HapK k141_20142_3 1042377.AFPJ01000008_gene2015 8.2e-97 288.0 COG0625@1|root,COG0625@2|Bacteria,1N8CY@1224|Proteobacteria,1SCJJ@1236|Gammaproteobacteria,46BG0@72275|Alteromonadaceae 1236|Gammaproteobacteria O Glutathione S-transferase, N-terminal domain - - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C,GST_N_3 k141_20142_4 1042377.AFPJ01000008_gene2014 7.83e-136 387.0 2BFHU@1|root,329BM@2|Bacteria,1RFVJ@1224|Proteobacteria,1S5TY@1236|Gammaproteobacteria,46B2A@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_20142_5 1042377.AFPJ01000008_gene2013 1.83e-151 428.0 COG1335@1|root,COG1335@2|Bacteria,1MZUV@1224|Proteobacteria,1T013@1236|Gammaproteobacteria,469MI@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Isochorismatase family - - - - - - - - - - - - Isochorismatase k141_20142_6 1042377.AFPJ01000008_gene2012 3.55e-229 631.0 COG0726@1|root,COG0726@2|Bacteria,1MV3V@1224|Proteobacteria,1RS41@1236|Gammaproteobacteria,46A0I@72275|Alteromonadaceae 1236|Gammaproteobacteria G Polysaccharide deacetylase - - - - - - - - - - - - Polysacc_deac_1 k141_20142_7 1042377.AFPJ01000008_gene2011 5.28e-196 547.0 COG0726@1|root,COG0726@2|Bacteria,1MV3V@1224|Proteobacteria,1RZ7E@1236|Gammaproteobacteria,469DR@72275|Alteromonadaceae 1236|Gammaproteobacteria G Polysaccharide deacetylase - - - - - - - - - - - - Polysacc_deac_1 k141_17562_1 218284.CCDN010000002_gene2226 8.53e-105 315.0 COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,4H9SZ@91061|Bacilli,1ZAX7@1386|Bacillus 91061|Bacilli E Sodium alanine symporter yflA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03310 - - - - ko00000 2.A.25 - - Na_Ala_symp k141_36448_2 344747.PM8797T_29803 3.85e-19 84.7 COG1802@1|root,COG1802@2|Bacteria,2IYNR@203682|Planctomycetes 2|Bacteria K COG1802 Transcriptional regulators - - - - - - - - - - - - FCD,GntR k141_2078_1 218284.CCDN010000006_gene3570 5.66e-34 120.0 COG2259@1|root,COG2259@2|Bacteria,1VCS2@1239|Firmicutes,4HKRK@91061|Bacilli 91061|Bacilli S membrane - - - ko:K15977 - - - - ko00000 - - - DoxX k141_2078_2 218284.CCDN010000006_gene3569 3.23e-168 479.0 COG2199@1|root,COG3706@2|Bacteria,1V2QN@1239|Firmicutes,4HFY9@91061|Bacilli,1ZS2E@1386|Bacillus 91061|Bacilli T 5TMR of 5TMR-LYT yhcK1 - 2.7.7.65 ko:K18967 - - - - ko00000,ko01000,ko02000 9.B.34.1.1 - - 5TM-5TMR_LYT,GGDEF k141_31608_2 218284.CCDN010000002_gene1993 2.03e-172 491.0 COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,4HA70@91061|Bacilli,1ZCE3@1386|Bacillus 91061|Bacilli F Belongs to the GARS family purD - 6.3.4.13 ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144 RC00090,RC00166 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS05245,iYO844.BSU06530 GARS_A,GARS_C,GARS_N k141_10542_2 1280001.BAOA01000088_gene3616 3.12e-80 247.0 COG2265@1|root,COG2265@2|Bacteria,1MY45@1224|Proteobacteria,1RN2B@1236|Gammaproteobacteria,1XSB1@135623|Vibrionales 135623|Vibrionales J Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA) trmA GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 2.1.1.35 ko:K00557 - - - - ko00000,ko01000,ko03016 - - - tRNA_U5-meth_tr k141_1167_1 1382305.AZUC01000046_gene596 9.41e-18 92.0 COG1404@1|root,COG1404@2|Bacteria,1TPH1@1239|Firmicutes,4HBQH@91061|Bacilli,26GW2@186818|Planococcaceae 91061|Bacilli O Peptidase inhibitor I9 prtS - 3.4.21.110,3.4.21.96 ko:K01361,ko:K08652 - - - - ko00000,ko01000,ko01002,ko03110 - - - FIVAR,Gram_pos_anchor,Inhibitor_I9,PA,Peptidase_S8,SLH,YSIRK_signal,fn3_5 k141_20143_1 1042377.AFPJ01000034_gene2321 6.39e-80 241.0 COG1075@1|root,COG1075@2|Bacteria,1R75P@1224|Proteobacteria,1SDJJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S acetyltransferases and hydrolases with the alpha beta hydrolase fold - - 3.1.1.3 ko:K01046 ko00561,ko01100,map00561,map01100 M00098 R02250,R02687 RC00020,RC00037,RC00041,RC00094 ko00000,ko00001,ko00002,ko01000 - - - Abhydrolase_1,Lipase_2,PGAP1 k141_34312_1 929562.Emtol_3681 5.84e-41 151.0 COG0531@1|root,COG0531@2|Bacteria,4NIZB@976|Bacteroidetes,47NQE@768503|Cytophagia 976|Bacteroidetes E Amino acid permease - - - ko:K03294,ko:K03758 - - - - ko00000,ko02000 2.A.3.2 - - AA_permease_2 k141_13037_1 42565.FP66_10580 1.72e-94 289.0 COG0860@1|root,COG1388@1|root,COG0860@2|Bacteria,COG1388@2|Bacteria,1MUQK@1224|Proteobacteria,1RMP1@1236|Gammaproteobacteria,1XHQX@135619|Oceanospirillales 135619|Oceanospirillales M N-acetylmuramoyl-L-alanine amidase amiB - 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - AMIN,Amidase_3,LysM k141_17563_1 1192034.CAP_2430 1.45e-15 79.0 COG0746@1|root,COG0746@2|Bacteria,1RKCH@1224|Proteobacteria,42T8X@68525|delta/epsilon subdivisions,2X9X1@28221|Deltaproteobacteria,2YW7C@29|Myxococcales 28221|Deltaproteobacteria H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor mobA - 2.7.7.77 ko:K03752 ko00790,ko01100,map00790,map01100 - R11581 - ko00000,ko00001,ko01000 - - - NTP_transf_3 k141_4534_2 1307436.PBF_02375 2.63e-101 303.0 COG1090@1|root,COG1090@2|Bacteria,1TRCE@1239|Firmicutes,4HBRT@91061|Bacilli,1ZBKW@1386|Bacillus 91061|Bacilli S nucleoside-diphosphate sugar epimerase yfhF - - ko:K07071 - - - - ko00000 - - - DUF1731,Epimerase k141_24849_1 1307436.PBF_14139 2.33e-08 52.4 COG3237@1|root,COG3237@2|Bacteria,1UAX9@1239|Firmicutes,4IMA5@91061|Bacilli,1ZJKY@1386|Bacillus 91061|Bacilli S CsbD-like - - - - - - - - - - - - CsbD k141_28174_1 1279017.AQYJ01000023_gene3247 6.32e-96 305.0 COG4223@1|root,COG4223@2|Bacteria,1N10X@1224|Proteobacteria,1RYCQ@1236|Gammaproteobacteria,46D2D@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF1631) - - - - - - - - - - - - DUF1631 k141_15170_1 42565.FP66_02115 2.66e-102 300.0 COG0689@1|root,COG0689@2|Bacteria,1MVFZ@1224|Proteobacteria,1RNTB@1236|Gammaproteobacteria,1XI8X@135619|Oceanospirillales 135619|Oceanospirillales J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates rph - 2.7.7.56 ko:K00989 - - - - ko00000,ko01000,ko03016 - - - RNase_PH,RNase_PH_C k141_13049_1 1294265.JCM21738_3701 2.79e-112 328.0 COG1005@1|root,COG1005@2|Bacteria,1TQNU@1239|Firmicutes,4HC8R@91061|Bacilli,1ZEMJ@1386|Bacillus 91061|Bacilli C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone nuoH GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 ko:K00337 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - NADHdh k141_35645_2 351348.Maqu_1662 1.47e-98 300.0 COG2079@1|root,COG2079@2|Bacteria,1MUIG@1224|Proteobacteria,1RPQN@1236|Gammaproteobacteria,4660P@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein involved in propionate catabolism prpD GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019679,GO:0019752,GO:0032787,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0046459,GO:0047547,GO:0048037,GO:0051536,GO:0051537,GO:0051540,GO:0071704,GO:0072329,GO:1901575 4.2.1.79 ko:K01720 ko00640,map00640 - R04424 RC01152 ko00000,ko00001,ko01000 - - iEcolC_1368.EcolC_3291 MmgE_PrpD k141_4538_3 1042377.AFPJ01000037_gene2983 8.79e-65 208.0 COG4520@1|root,COG4520@2|Bacteria,1N0YF@1224|Proteobacteria,1SAAR@1236|Gammaproteobacteria 1236|Gammaproteobacteria M 17 kDa surface antigen - - - - - - - - - - - - 17kDa_Anti_2,Gly-zipper_Omp,Rick_17kDa_Anti,SH3_3 k141_4538_4 1279017.AQYJ01000021_gene2907 0.0 942.0 COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,1RNYW@1236|Gammaproteobacteria,46415@72275|Alteromonadaceae 1236|Gammaproteobacteria OU COG0616 Periplasmic serine proteases (ClpP class) sppA GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0010467,GO:0016020,GO:0016021,GO:0016485,GO:0016787,GO:0019538,GO:0031224,GO:0031226,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 - ko:K04773 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S49 k141_4538_5 1042377.AFPJ01000037_gene2980 4.63e-49 159.0 COG3308@1|root,COG3308@2|Bacteria,1N5UB@1224|Proteobacteria,1SAAJ@1236|Gammaproteobacteria,4693B@72275|Alteromonadaceae 1236|Gammaproteobacteria S Predicted membrane protein (DUF2069) - - - - - - - - - - - - DUF2069 k141_4538_6 1279017.AQYJ01000021_gene2909 1.85e-105 308.0 COG0655@1|root,COG0655@2|Bacteria,1MW7N@1224|Proteobacteria,1S23B@1236|Gammaproteobacteria,466IM@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the WrbA family wrbA - 1.6.5.2 ko:K03809 ko00130,ko01110,map00130,map01110 - R02964,R03643,R03816 RC00819 ko00000,ko00001,ko01000 - - - FMN_red k141_4538_8 1042377.AFPJ01000037_gene2977 2.54e-215 607.0 COG1295@1|root,COG1295@2|Bacteria,1QICW@1224|Proteobacteria,1RMKI@1236|Gammaproteobacteria,4669T@72275|Alteromonadaceae 1236|Gammaproteobacteria S membrane rbn GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K07058 - - - - ko00000 - - - Virul_fac_BrkB k141_4538_9 523791.Kkor_1633 1.07e-23 96.3 COG0526@1|root,COG0526@2|Bacteria,1N726@1224|Proteobacteria,1SD4C@1236|Gammaproteobacteria,1XM5E@135619|Oceanospirillales 135619|Oceanospirillales O AhpC/TSA family - - - - - - - - - - - - AhpC-TSA k141_4538_10 1279017.AQYJ01000021_gene2913 1.95e-232 650.0 COG1823@1|root,COG1823@2|Bacteria,1R3F8@1224|Proteobacteria,1RMHV@1236|Gammaproteobacteria,465XI@72275|Alteromonadaceae 1236|Gammaproteobacteria U Sodium:dicarboxylate symporter family ydjN GO:0000099,GO:0000101,GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006791,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015184,GO:0015318,GO:0015711,GO:0015804,GO:0015807,GO:0015811,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072337,GO:0072348,GO:0072349,GO:0098656,GO:1901682,GO:1902475,GO:1903825,GO:1905039 - ko:K06956 - - - - ko00000 - - - SDF k141_4538_11 1117647.M5M_17095 3.22e-71 224.0 COG3208@1|root,COG3208@2|Bacteria,1R027@1224|Proteobacteria,1T4E8@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q Thioesterase involved in non-ribosomal peptide biosynthesis - - - - - - - - - - - - Abhydrolase_1 k141_4538_12 1279017.AQYJ01000021_gene2919 1.51e-45 155.0 COG3134@1|root,COG3134@2|Bacteria,1MVWD@1224|Proteobacteria,1RQR9@1236|Gammaproteobacteria,468W9@72275|Alteromonadaceae 1236|Gammaproteobacteria S Glycine zipper 2TM domain - - - - - - - - - - - - Rick_17kDa_Anti k141_4538_14 1279017.AQYJ01000021_gene2921 2.36e-143 406.0 COG0745@1|root,COG0745@2|Bacteria,1N0YI@1224|Proteobacteria,1RMWT@1236|Gammaproteobacteria,4649A@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain phoP - - ko:K02483,ko:K07660 ko01503,ko02020,map01503,map02020 M00444,M00709,M00721,M00723,M00724,M00744 - - ko00000,ko00001,ko00002,ko01504,ko02022 - - - Response_reg,Trans_reg_C k141_4538_15 1279017.AQYJ01000021_gene2922 2.13e-226 635.0 COG0642@1|root,COG2205@2|Bacteria,1QTVU@1224|Proteobacteria,1RPFY@1236|Gammaproteobacteria,4653U@72275|Alteromonadaceae 1236|Gammaproteobacteria T Signal transduction histidine kinase phoQ GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010350,GO:0016020,GO:0016021,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0031224,GO:0031226,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0035556,GO:0036211,GO:0042578,GO:0042594,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046777,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071496,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.7.13.3 ko:K07637 ko01503,ko02020,map01503,map02020 M00444,M00709,M00721,M00723,M00724,M00744 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 - - - HATPase_c,HisKA,PhoQ_Sensor k141_4538_16 1279017.AQYJ01000021_gene2923 6.93e-317 876.0 COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,1RPHJ@1236|Gammaproteobacteria,464JR@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1960 Acyl-CoA dehydrogenases bcd - 1.3.8.1 ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 - R01175,R01178,R02661,R03172,R04751 RC00052,RC00068,RC00076,RC00120,RC00148 ko00000,ko00001,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N k141_4538_17 1453501.JELR01000001_gene1868 8.76e-166 473.0 COG0707@1|root,COG0707@2|Bacteria,1MWQP@1224|Proteobacteria,1T31H@1236|Gammaproteobacteria,46D2Z@72275|Alteromonadaceae 1236|Gammaproteobacteria M Glycosyl transferase family 1 - - - - - - - - - - - - Glyco_trans_1_3 k141_3332_1 42565.FP66_10695 3.7e-133 397.0 COG2274@1|root,COG2274@2|Bacteria,1R2T0@1224|Proteobacteria,1SBE1@1236|Gammaproteobacteria,1XIJU@135619|Oceanospirillales 135619|Oceanospirillales V (ABC) transporter - - - ko:K12541 ko02010,map02010 M00330 - - ko00000,ko00001,ko00002,ko02000,ko02044 3.A.1.109.3,3.A.1.109.4 - - ABC_membrane,ABC_tran,Peptidase_C39 k141_17593_1 1453501.JELR01000002_gene967 3.59e-103 307.0 COG0517@1|root,COG0517@2|Bacteria,1MXI6@1224|Proteobacteria,1S0AJ@1236|Gammaproteobacteria,46DNA@72275|Alteromonadaceae 1236|Gammaproteobacteria S Putative transposase - - - - - - - - - - - - Y2_Tnp,Zn_Tnp_IS91 k141_21111_1 1453501.JELR01000002_gene1431 2.21e-170 491.0 COG0427@1|root,COG1670@1|root,COG0427@2|Bacteria,COG1670@2|Bacteria,1MUGE@1224|Proteobacteria,1RP19@1236|Gammaproteobacteria,46429@72275|Alteromonadaceae 1236|Gammaproteobacteria C acetyl-CoA hydrolase - - - ko:K18288 ko00660,map00660 - R02407,R10600 RC00012,RC00014 ko00000,ko00001,ko01000 - - - AcetylCoA_hyd_C,AcetylCoA_hydro,Acetyltransf_1,Acetyltransf_3 k141_33056_1 218284.CCDN010000001_gene719 2.43e-21 89.0 COG4976@1|root,COG4976@2|Bacteria,1UHZM@1239|Firmicutes,4ISBD@91061|Bacilli,1ZS4Q@1386|Bacillus 91061|Bacilli S Methyltransferase domain - - - - - - - - - - - - Methyltransf_25 k141_33056_2 218284.CCDN010000001_gene718 2.23e-80 238.0 COG0799@1|root,COG0799@2|Bacteria,1VA2Z@1239|Firmicutes,4HKEJ@91061|Bacilli,1ZGYR@1386|Bacillus 91061|Bacilli J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation rsfS GO:0003674,GO:0005488,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113 - ko:K09710 - - - - ko00000,ko03009 - - - RsfS k141_31616_1 1294265.JCM21738_4040 5.44e-47 160.0 COG0707@1|root,COG0707@2|Bacteria,1TQFT@1239|Firmicutes,4HBAQ@91061|Bacilli,1ZBA5@1386|Bacillus 91061|Bacilli M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) murG - 2.4.1.227 ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 - R05032,R05662 RC00005,RC00049 ko00000,ko00001,ko01000,ko01011 - GT28 - Glyco_tran_28_C,Glyco_transf_28 k141_31616_2 935836.JAEL01000011_gene5182 5.53e-160 454.0 COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,4HAD8@91061|Bacilli,1ZC3F@1386|Bacillus 91061|Bacilli M cell wall formation murB - 1.3.1.98 ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R03191,R03192 RC02639 ko00000,ko00001,ko01000,ko01011 - - iYO844.BSU15230 FAD_binding_4,MurB_C k141_20162_1 1279017.AQYJ01000028_gene2279 3.27e-233 660.0 COG0366@1|root,COG0366@2|Bacteria,1Q8Y2@1224|Proteobacteria,1RQV0@1236|Gammaproteobacteria,464WX@72275|Alteromonadaceae 1236|Gammaproteobacteria G Alpha amylase, catalytic domain - - - - - - - - - - - - Alpha-amylase,Alpha-amylase_C,Malt_amylase_C k141_16484_2 1238450.VIBNISOn1_1670021 6.54e-78 252.0 COG1874@1|root,COG1874@2|Bacteria,1MUVR@1224|Proteobacteria,1RPW9@1236|Gammaproteobacteria 1236|Gammaproteobacteria G beta-galactosidase bglY - 3.2.1.23 ko:K12308 ko00052,map00052 - R01105 RC00452 ko00000,ko00001,ko01000 - - - Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M k141_29589_1 283699.D172_3414 1.04e-30 118.0 COG1714@1|root,COG1714@2|Bacteria,1NB1Z@1224|Proteobacteria,1TC4P@1236|Gammaproteobacteria,2Q4DR@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria S RDD family - - - - - - - - - - - - RDD k141_29589_2 1042377.AFPJ01000013_gene1741 3e-46 157.0 COG1432@1|root,COG1432@2|Bacteria,1MX5C@1224|Proteobacteria,1RSP8@1236|Gammaproteobacteria,46600@72275|Alteromonadaceae 1236|Gammaproteobacteria S OST-HTH/LOTUS domain - - - - - - - - - - - - NYN,OST-HTH k141_24885_2 218284.CCDN010000005_gene3355 1.36e-80 241.0 2C0DW@1|root,30W9V@2|Bacteria,1V5EY@1239|Firmicutes,4HI10@91061|Bacilli,1ZQRY@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_1186_1 1453501.JELR01000001_gene2016 9.48e-101 311.0 COG4776@1|root,COG4776@2|Bacteria,1P563@1224|Proteobacteria,1RP5G@1236|Gammaproteobacteria,46DF9@72275|Alteromonadaceae 1236|Gammaproteobacteria K RNB rnb GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0008859,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360,GO:1901361,GO:1901575 3.1.13.1 ko:K01147 - - - - ko00000,ko01000,ko03016 - - - OB_RNB,RNB,S1 k141_13050_1 218284.CCDN010000007_gene3998 2.4e-80 241.0 COG0712@1|root,COG0712@2|Bacteria,1VAG3@1239|Firmicutes,4HKFW@91061|Bacilli,1ZG65@1386|Bacillus 91061|Bacilli C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpH - - ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - OSCP k141_4539_2 272952.HpaP802370 1.12e-34 130.0 COG1905@1|root,KOG3196@2759|Eukaryota,3Q9U6@4776|Peronosporales 4776|Peronosporales C Thioredoxin-like [2Fe-2S] ferredoxin - - 1.6.5.3,1.6.99.3 ko:K03943 ko00190,ko01100,ko04714,ko04723,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04714,map04723,map04932,map05010,map05012,map05016 M00143 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1.6 - - 2Fe-2S_thioredx k141_33057_1 1294265.JCM21738_101 1.17e-114 334.0 28IBV@1|root,2Z8EA@2|Bacteria,1TPCJ@1239|Firmicutes,4HB3C@91061|Bacilli,1ZBT4@1386|Bacillus 91061|Bacilli S YIEGIA protein yphB - - ko:K05739 - - - - ko00000 - - - YIEGIA k141_35646_1 1415779.JOMH01000001_gene2672 5.2e-09 63.5 COG4966@1|root,COG4966@2|Bacteria,1R5YK@1224|Proteobacteria,1RZIZ@1236|Gammaproteobacteria,1X8AT@135614|Xanthomonadales 135614|Xanthomonadales NU Type IV Pilus-assembly protein W - - - - - - - - - - - - N_methyl,PilW k141_35646_2 1279017.AQYJ01000019_gene1507 2.52e-36 128.0 COG4967@1|root,COG4967@2|Bacteria,1N0HC@1224|Proteobacteria,1SAPN@1236|Gammaproteobacteria,468BB@72275|Alteromonadaceae 1236|Gammaproteobacteria NU Prokaryotic N-terminal methylation motif pilV - - ko:K02671 - - - - ko00000,ko02035,ko02044 - - - N_methyl k141_21112_1 1294265.JCM21738_472 3.33e-119 358.0 COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,4H9SP@91061|Bacilli,1ZAPS@1386|Bacillus 91061|Bacilli P COG2217 Cation transport ATPase zosA - 3.6.3.3,3.6.3.5 ko:K01534 - - - - ko00000,ko01000 3.A.3.6 - - E1-E2_ATPase,Hydrolase k141_20163_1 1042377.AFPJ01000012_gene1370 1.44e-75 227.0 COG2010@1|root,COG2010@2|Bacteria 2|Bacteria C Cytochrome c - - - ko:K00405 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002 3.D.4.3 - - Cytochrom_C,Cytochrome_CBB3,FixO,Lipoprotein_15 k141_20163_2 1042377.AFPJ01000012_gene1369 1.31e-09 57.0 2C46F@1|root,32SRD@2|Bacteria,1N540@1224|Proteobacteria,1S8P6@1236|Gammaproteobacteria,46CCG@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_2101_1 1128421.JAGA01000003_gene2923 4.51e-173 501.0 COG1053@1|root,COG1053@2|Bacteria,2NQMR@2323|unclassified Bacteria 2|Bacteria C Fumarate reductase flavoprotein C-term sdhA - 1.3.5.1,1.3.5.4 ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C k141_15171_1 1340434.AXVA01000001_gene1148 5.13e-74 239.0 COG1263@1|root,COG2190@1|root,COG1263@2|Bacteria,COG2190@2|Bacteria,1TPJ8@1239|Firmicutes,4HA8X@91061|Bacilli,1ZAZ3@1386|Bacillus 91061|Bacilli G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific nagE - 2.7.1.193,2.7.1.199 ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 M00267,M00809 R02738,R05199 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.13,4.A.1.1.14,4.A.1.1.15,4.A.1.1.2,4.A.1.1.5,4.A.1.1.7,4.A.1.1.9 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC k141_31617_1 1123228.AUIH01000096_gene1756 4.85e-41 144.0 COG0501@1|root,COG0501@2|Bacteria,1MUNA@1224|Proteobacteria,1RMZ6@1236|Gammaproteobacteria,1XIXM@135619|Oceanospirillales 135619|Oceanospirillales O peptidase - - - - - - - - - - - - Peptidase_M48 k141_13051_1 1169144.KB910940_gene2537 3.04e-98 304.0 COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4H9ZK@91061|Bacilli,1ZCFC@1386|Bacillus 91061|Bacilli S ABC transporter - - - - - - - - - - - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn k141_3333_2 1219076.N646_1396 5.96e-38 139.0 COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,1SYC8@1236|Gammaproteobacteria,1XVG3@135623|Vibrionales 135623|Vibrionales U Sulfate permease family - - - - - - - - - - - - STAS,Sulfate_transp k141_21113_1 518766.Rmar_1656 3.29e-63 216.0 COG0019@1|root,COG0527@1|root,COG0019@2|Bacteria,COG0527@2|Bacteria,4NFWR@976|Bacteroidetes,1FIKN@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes E Belongs to the Orn Lys Arg decarboxylase class-II family - - 2.7.2.4,4.1.1.20 ko:K00928,ko:K12526 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00451,R00480 RC00002,RC00043,RC00299 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,Orn_Arg_deC_N,Orn_DAP_Arg_deC k141_24887_1 1169144.KB910938_gene1462 2.77e-88 273.0 COG3356@1|root,COG3356@2|Bacteria,1V42W@1239|Firmicutes,4HK1K@91061|Bacilli,1ZMFS@1386|Bacillus 91061|Bacilli S Neutral/alkaline non-lysosomal ceramidase, N-terminal - - - - - - - - - - - - Ceramidase_alk k141_10558_2 1280001.BAOA01000072_gene2775 6.83e-190 528.0 COG2116@1|root,COG2116@2|Bacteria,1MU0W@1224|Proteobacteria,1RQ6K@1236|Gammaproteobacteria,1XVKN@135623|Vibrionales 135623|Vibrionales P COG2116 Formate nitrite family of transporters - - - - - - - - - - - - Form_Nir_trans k141_10558_3 1219076.N646_4364 3.07e-71 214.0 COG2146@1|root,COG2146@2|Bacteria,1MZBY@1224|Proteobacteria,1S9F1@1236|Gammaproteobacteria,1XXY2@135623|Vibrionales 135623|Vibrionales P COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases nirD - 1.7.1.15 ko:K00363 ko00910,ko01120,map00910,map01120 M00530 R00787 RC00176 ko00000,ko00001,ko00002,ko01000 - - - Rieske_2 k141_10558_4 1116375.VEJY3_19561 0.0 1668.0 COG1251@1|root,COG1251@2|Bacteria,1MW58@1224|Proteobacteria,1RNGY@1236|Gammaproteobacteria,1XUM5@135623|Vibrionales 135623|Vibrionales C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family nirB - 1.7.1.15 ko:K00362 ko00910,ko01120,map00910,map01120 M00530 R00787 RC00176 ko00000,ko00001,ko00002,ko01000 - - - Fer2_BFD,NIR_SIR,NIR_SIR_ferr,Pyr_redox_2 k141_10558_5 1116375.VEJY3_19556 9.64e-72 217.0 COG0782@1|root,COG0782@2|Bacteria,1MZNY@1224|Proteobacteria,1S8V4@1236|Gammaproteobacteria,1XX79@135623|Vibrionales 135623|Vibrionales K Rnk N-terminus - - - ko:K06140 - - - - ko00000,ko03000 - - - GreA_GreB,Rnk_N k141_33058_1 1384049.CD29_16580 4.28e-13 67.0 COG1247@1|root,COG1247@2|Bacteria,1VAAC@1239|Firmicutes,4HJ6D@91061|Bacilli,3IYMA@400634|Lysinibacillus 91061|Bacilli M acetyltransferase - - - - - - - - - - - - Acetyltransf_1 k141_31618_1 857087.Metme_2701 2.38e-28 117.0 COG1858@1|root,COG1858@2|Bacteria,1RC4D@1224|Proteobacteria,1SJKT@1236|Gammaproteobacteria,1XFYK@135618|Methylococcales 135618|Methylococcales C cytochrome C peroxidase - - - - - - - - - - - - - k141_28396_2 1131730.BAVI_16447 1.69e-109 322.0 COG1277@1|root,COG1277@2|Bacteria,1UNKX@1239|Firmicutes,4IUHM@91061|Bacilli,1ZD4E@1386|Bacillus 91061|Bacilli S ABC-2 family transporter protein - - - - - - - - - - - - ABC2_membrane_2 k141_21357_1 796606.BMMGA3_15665 2.12e-64 199.0 COG3832@1|root,COG3832@2|Bacteria,1V587@1239|Firmicutes,4HJ9S@91061|Bacilli,1ZGJJ@1386|Bacillus 91061|Bacilli S Activator of Hsp90 ATPase homolog 1-like protein - - - - - - - - - - - - AHSA1 k141_21357_2 1123290.AUDQ01000024_gene3220 6.99e-74 224.0 COG3832@1|root,COG3832@2|Bacteria,1VV5D@1239|Firmicutes,4IDSK@91061|Bacilli,26HDE@186818|Planococcaceae 91061|Bacilli S Polyketide cyclase / dehydrase and lipid transport - - - - - - - - - - - - Polyketide_cyc2 k141_36659_1 1294265.JCM21738_2793 4.89e-115 335.0 COG1039@1|root,COG1039@2|Bacteria,1TQBE@1239|Firmicutes,4H9QR@91061|Bacilli,1ZBHW@1386|Bacillus 91061|Bacilli L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhC GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03471 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DUF3378,RNase_HII k141_15322_1 218284.CCDN010000007_gene4022 3.93e-53 167.0 2EK0E@1|root,33DQZ@2|Bacteria,1VMAH@1239|Firmicutes,4HRG1@91061|Bacilli,1ZJ42@1386|Bacillus 91061|Bacilli S DNA-directed RNA polymerase subunit beta - - - - - - - - - - - - EpuA k141_15322_2 218284.CCDN010000007_gene4021 1.12e-66 210.0 COG4786@1|root,COG4786@2|Bacteria,1TSYY@1239|Firmicutes,4HC6B@91061|Bacilli,1ZCIJ@1386|Bacillus 91061|Bacilli N flagellar basal body flhP GO:0001539,GO:0005575,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009424,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588 - ko:K02392 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C k141_30638_1 1453501.JELR01000001_gene2703 0.0 1751.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,465T2@72275|Alteromonadaceae 1236|Gammaproteobacteria V AcrB/AcrD/AcrF family - - - - - - - - - - - - ACR_tran k141_30638_2 1453501.JELR01000001_gene2702 5.57e-179 509.0 COG0845@1|root,COG0845@2|Bacteria,1PEVY@1224|Proteobacteria,1RPEQ@1236|Gammaproteobacteria,465PN@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - - - - - - - - - - Biotin_lipoyl_2,HlyD_3 k141_30638_3 1453501.JELR01000002_gene566 0.0 1273.0 COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,1RNA5@1236|Gammaproteobacteria,4641A@72275|Alteromonadaceae 1236|Gammaproteobacteria P Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity katG GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.11.1.21 ko:K03782 ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110 - R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906 RC00034,RC00213,RC00767,RC02141 ko00000,ko00001,ko01000 - - - peroxidase k141_30638_4 631362.Thi970DRAFT_04432 2.71e-150 438.0 COG3263@1|root,COG3263@2|Bacteria,1MVKV@1224|Proteobacteria,1T2D1@1236|Gammaproteobacteria,1X28U@135613|Chromatiales 135613|Chromatiales P Sodium/hydrogen exchanger family - - - ko:K11105 - - - - ko00000,ko02000 2.A.36.6 - - Na_H_Exchanger k141_3536_1 218284.CCDN010000002_gene2593 9.6e-92 281.0 COG0642@1|root,COG2205@2|Bacteria,1V10X@1239|Firmicutes,4H9UD@91061|Bacilli,1ZS4A@1386|Bacillus 91061|Bacilli T COG0642 Signal transduction histidine kinase yclK - - - - - - - - - - - HAMP,HATPase_c,HisKA k141_2369_1 1348908.KI518619_gene1063 6.93e-23 92.8 COG1145@1|root,32SB1@2|Bacteria,1V6N0@1239|Firmicutes,4HIWV@91061|Bacilli,1ZIM7@1386|Bacillus 91061|Bacilli C COG1145 Ferredoxin - - - - - - - - - - - - DUF326 k141_28399_1 218284.CCDN010000005_gene3251 8.77e-204 573.0 COG0366@1|root,COG0366@2|Bacteria,1TSVI@1239|Firmicutes,4HCV2@91061|Bacilli,1ZDR6@1386|Bacillus 91061|Bacilli G Alpha amylase, catalytic domain - - 3.2.1.1 ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 - R02108,R02112,R11262 - ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,Malt_amylase_C k141_15323_1 1294265.JCM21738_1887 4.68e-133 384.0 COG2358@1|root,COG2358@2|Bacteria,1TPXW@1239|Firmicutes,4HB7U@91061|Bacilli,1ZEBW@1386|Bacillus 91061|Bacilli S NMT1-like family - - - ko:K07080 - - - - ko00000 - - - NMT1_3 k141_33278_1 1279017.AQYJ01000029_gene3333 1.74e-55 184.0 COG4798@1|root,COG4798@2|Bacteria,1NNHX@1224|Proteobacteria,1RN1A@1236|Gammaproteobacteria,465Q4@72275|Alteromonadaceae 1236|Gammaproteobacteria S Methyltransferase - - - - - - - - - - - - - k141_33278_2 1492922.GY26_02725 9.6e-47 152.0 COG0011@1|root,COG0011@2|Bacteria,1N1NM@1224|Proteobacteria,1SAV8@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Thiamine-binding protein - - - - - - - - - - - - Thiamine_BP k141_33278_6 1279017.AQYJ01000029_gene3328 1.38e-122 371.0 COG0665@1|root,COG4121@1|root,COG0665@2|Bacteria,COG4121@2|Bacteria,1MZW5@1224|Proteobacteria,1RMTE@1236|Gammaproteobacteria,464VK@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 mnmC GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0004808,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016491,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363 2.1.1.61 ko:K15461 - - R00601,R08702 RC00003,RC00053,RC00060,RC01483 ko00000,ko01000,ko03016 - - - DAO,Methyltransf_30 k141_2370_1 218284.CCDN010000001_gene1118 4.92e-131 382.0 COG0287@1|root,COG0287@2|Bacteria,1TPXG@1239|Firmicutes,4HBI4@91061|Bacilli,1ZBVZ@1386|Bacillus 91061|Bacilli E prephenate dehydrogenase tyrA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.3.1.12 ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00025 R01728 RC00125 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU22610 ACT,PDH k141_28400_1 501479.ACNW01000098_gene1165 4.32e-22 94.4 COG0277@1|root,COG0277@2|Bacteria,1MVYV@1224|Proteobacteria,2TRA7@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Glycolate oxidase glcE - - ko:K11472 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001 - - - FAD-oxidase_C,FAD_binding_4 k141_28400_2 388399.SSE37_18190 2.13e-55 186.0 COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2TSG6@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Glycolate oxidase subunit glcD - 1.1.3.15 ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001,ko01000 - - - FAD-oxidase_C,FAD_binding_4 k141_33279_2 986075.CathTA2_2786 1.65e-11 60.5 COG1609@1|root,COG1609@2|Bacteria,1VADF@1239|Firmicutes,4HKIY@91061|Bacilli 91061|Bacilli K Stage III sporulation protein D spoIIID - - ko:K06283 - - - - ko00000,ko03000 - - - SpoIIID k141_3537_1 218284.CCDN010000005_gene3351 3.6e-237 664.0 COG1757@1|root,COG1757@2|Bacteria,1TQ3B@1239|Firmicutes,4HA18@91061|Bacilli,1ZBQN@1386|Bacillus 91061|Bacilli C Na H antiporter nhaC - - ko:K03315 - - - - ko00000,ko02000 2.A.35 - - Na_H_antiporter k141_4749_1 218284.CCDN010000002_gene2066 4.61e-125 365.0 COG0584@1|root,COG0584@2|Bacteria,1TQ3Y@1239|Firmicutes,4HAI9@91061|Bacilli,1ZEY9@1386|Bacillus 91061|Bacilli C Glycerophosphoryl diester phosphodiesterase family - - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - GDPD k141_4749_2 218284.CCDN010000002_gene2067 1.7e-95 288.0 COG0055@1|root,COG0055@2|Bacteria,1UATS@1239|Firmicutes,4HBRA@91061|Bacilli,1ZDEJ@1386|Bacillus 91061|Bacilli C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits - - 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - HTH_26 k141_33280_1 318167.Sfri_0205 9.52e-40 141.0 COG1741@1|root,COG1741@2|Bacteria,1MVSW@1224|Proteobacteria,1RNVS@1236|Gammaproteobacteria,2Q915@267890|Shewanellaceae 1236|Gammaproteobacteria S Belongs to the pirin family yhhW GO:0003674,GO:0003824,GO:0008127,GO:0008150,GO:0008152,GO:0016491,GO:0016701,GO:0016702,GO:0051213,GO:0055114 - ko:K06911 - - - - ko00000 - - - Pirin k141_4750_1 218284.CCDN010000001_gene1867 4.2e-164 470.0 COG3845@1|root,COG3845@2|Bacteria,1UYQA@1239|Firmicutes,4HVSH@91061|Bacilli,1ZS12@1386|Bacillus 91061|Bacilli S ABC transporter, ATP-binding protein yufO - 3.6.3.17 ko:K02056 - M00221 - - ko00000,ko00002,ko01000,ko02000 3.A.1.2 - - ABC_tran k141_31777_1 218284.CCDN010000001_gene132 1.93e-115 360.0 COG1038@1|root,COG1038@2|Bacteria,1UHP9@1239|Firmicutes,4IS56@91061|Bacilli,1ZC4R@1386|Bacillus 91061|Bacilli C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second pyc - 6.4.1.1 ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 M00173 R00344 RC00040,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,HMGL-like,PYC_OADA k141_28402_1 1116375.VEJY3_00805 2.48e-125 361.0 COG0444@1|root,COG0444@2|Bacteria,1R4KB@1224|Proteobacteria,1SMBI@1236|Gammaproteobacteria,1XTVM@135623|Vibrionales 135623|Vibrionales P Belongs to the ABC transporter superfamily dppD - - ko:K02031 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - ABC_tran,oligo_HPY k141_28402_2 674977.VMC_14260 3.19e-62 197.0 COG4608@1|root,COG4608@2|Bacteria,1NU4K@1224|Proteobacteria,1SKPD@1236|Gammaproteobacteria,1XTTK@135623|Vibrionales 135623|Vibrionales P COG4608 ABC-type oligopeptide transport system, ATPase component - - - ko:K02032 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - ABC_tran,oligo_HPY k141_2374_2 1034347.CAHJ01000010_gene2129 3.59e-21 90.1 COG1561@1|root,COG1561@2|Bacteria,1TQHJ@1239|Firmicutes,4HAK9@91061|Bacilli,1ZCGE@1386|Bacillus 91061|Bacilli S stress-induced protein yloC - - - - - - - - - - - DUF1732,YicC_N k141_30639_2 1116375.VEJY3_06725 1.68e-224 618.0 COG0726@1|root,COG0726@2|Bacteria,1MV3V@1224|Proteobacteria,1RPKM@1236|Gammaproteobacteria,1XTIJ@135623|Vibrionales 135623|Vibrionales G Polysaccharide deacetylase - - 3.5.1.104 ko:K22278 - - - - ko00000,ko01000 - - - Polysacc_deac_1 k141_28403_1 218284.CCDN010000001_gene1000 3.83e-122 361.0 COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,4HC50@91061|Bacilli,1ZQ98@1386|Bacillus 91061|Bacilli I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) yqjD GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016421,GO:0016874,GO:0016885,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0071704,GO:0072329,GO:1901575 2.1.3.15,6.4.1.3 ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 M00373,M00741 R01859 RC00097,RC00609 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans k141_31778_1 1294265.JCM21738_47 2.84e-84 253.0 COG1187@1|root,COG1187@2|Bacteria,1TP68@1239|Firmicutes,4H9MU@91061|Bacilli,1ZBNQ@1386|Bacillus 91061|Bacilli J Belongs to the pseudouridine synthase RsuA family rluB GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.22 ko:K06178 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 k141_2375_1 218284.CCDN010000005_gene3187 7.63e-126 362.0 COG4758@1|root,COG4758@2|Bacteria,1TSDR@1239|Firmicutes,4HCRP@91061|Bacilli,1ZE5M@1386|Bacillus 91061|Bacilli S Cell wall-active antibiotics response 4TMS YvqF - - - ko:K11622 ko02020,map02020 - - - ko00000,ko00001 - - - DUF2154 k141_28404_1 218284.CCDN010000007_gene3824 1.55e-106 321.0 COG0739@1|root,COG0739@2|Bacteria,1TRWJ@1239|Firmicutes,4HB43@91061|Bacilli,1ZBXH@1386|Bacillus 91061|Bacilli M G5 nlpD - - - - - - - - - - - G5,LysM,Peptidase_M23 k141_33282_1 218284.CCDN010000005_gene3491 9.73e-46 157.0 COG1173@1|root,COG1173@2|Bacteria,1V21B@1239|Firmicutes,4HG7B@91061|Bacilli,1ZR0T@1386|Bacillus 91061|Bacilli EP Binding-protein-dependent transport system inner membrane component - - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 k141_33282_2 218284.CCDN010000005_gene3490 1.75e-113 335.0 COG0601@1|root,COG0601@2|Bacteria,1TRW4@1239|Firmicutes,4HEGZ@91061|Bacilli,1ZH5U@1386|Bacillus 91061|Bacilli EP Binding-protein-dependent transport system inner membrane component - - - ko:K02033 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 k141_3540_1 1116375.VEJY3_05395 2.79e-226 624.0 COG0583@1|root,COG0583@2|Bacteria,1MU8N@1224|Proteobacteria,1RN7T@1236|Gammaproteobacteria,1XTGJ@135623|Vibrionales 135623|Vibrionales K Transcriptional regulator cysB - - ko:K13634 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate k141_3540_2 223926.28806089 7.18e-87 266.0 2C7MP@1|root,2Z7Q4@2|Bacteria,1NHK1@1224|Proteobacteria,1RQ17@1236|Gammaproteobacteria,1XTB8@135623|Vibrionales 135623|Vibrionales S COG0500 SAM-dependent methyltransferases PP0279 - - - - - - - - - - - Methyltransf_32 k141_30641_1 218284.CCDN010000005_gene3274 1.24e-124 364.0 COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,4H9SD@91061|Bacilli,1ZD02@1386|Bacillus 91061|Bacilli I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP fabF - 2.3.1.179 ko:K09458,ko:K14660 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - iSB619.SA_RS04785 Ketoacyl-synt_C,ketoacyl-synt k141_8177_1 1116375.VEJY3_18231 1.03e-159 449.0 COG1028@1|root,COG1028@2|Bacteria,1MW9A@1224|Proteobacteria,1RMMZ@1236|Gammaproteobacteria,1XV9R@135623|Vibrionales 135623|Vibrionales IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - - - - - - - - - - adh_short_C2 k141_8177_2 1116375.VEJY3_07780 3.21e-84 251.0 COG2010@1|root,COG2010@2|Bacteria,1N0EF@1224|Proteobacteria,1SAAN@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Cytochrome c mono- and diheme variants - - - - - - - - - - - - Cytochrom_C k141_8177_3 1190603.AJYD01000015_gene991 2.67e-61 192.0 COG0454@1|root,COG0456@2|Bacteria,1N79D@1224|Proteobacteria,1SHVE@1236|Gammaproteobacteria,1XY01@135623|Vibrionales 135623|Vibrionales K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - - - - - - - - - - Acetyltransf_10 k141_8177_5 675812.VHA_002505 7.21e-30 110.0 2DDP4@1|root,2ZIRZ@2|Bacteria,1NK1H@1224|Proteobacteria,1SI15@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - ko:K03569 - - - - ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 - - - k141_8177_6 1187848.AJYQ01000143_gene1524 2.55e-44 147.0 2AWG4@1|root,31NCD@2|Bacteria,1QK3D@1224|Proteobacteria,1TI66@1236|Gammaproteobacteria,1XYGN@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_8177_7 1116375.VEJY3_18221 4.1e-98 286.0 COG2050@1|root,COG2050@2|Bacteria,1RBPE@1224|Proteobacteria,1SCN1@1236|Gammaproteobacteria,1XXCQ@135623|Vibrionales 135623|Vibrionales Q Thioesterase superfamily - - - - - - - - - - - - 4HBT k141_8177_8 1116375.VEJY3_18166 1.3e-116 335.0 COG2135@1|root,COG2135@2|Bacteria,1RER4@1224|Proteobacteria,1RSBH@1236|Gammaproteobacteria,1XXM4@135623|Vibrionales 135623|Vibrionales S Belongs to the SOS response-associated peptidase family - - - - - - - - - - - - SRAP k141_8177_9 1116375.VEJY3_18161 1.04e-227 629.0 COG1638@1|root,COG1638@2|Bacteria,1MVHI@1224|Proteobacteria,1RP9D@1236|Gammaproteobacteria,1XUMG@135623|Vibrionales 135623|Vibrionales G Bacterial extracellular solute-binding protein, family 7 - - - - - - - - - - - - DctP k141_8177_10 1116375.VEJY3_18156 3.19e-109 317.0 COG3090@1|root,COG3090@2|Bacteria,1MYII@1224|Proteobacteria,1S73D@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Tripartite ATP-independent periplasmic transporters, DctQ component - - - - - - - - - - - - DctQ k141_8177_11 1116375.VEJY3_18151 1.05e-278 765.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,1RM8E@1236|Gammaproteobacteria,1XV53@135623|Vibrionales 135623|Vibrionales G Tripartite ATP-independent periplasmic transporter, DctM component - - - - - - - - - - - - DctM k141_8177_12 1116375.VEJY3_18141 1.94e-164 464.0 COG2207@1|root,COG2207@2|Bacteria,1MXDJ@1224|Proteobacteria,1RNJM@1236|Gammaproteobacteria,1XY6U@135623|Vibrionales 135623|Vibrionales K helix_turn_helix, arabinose operon control protein - - - ko:K02508,ko:K18954 - - - - ko00000,ko03000 - - - AraC_binding,HTH_18 k141_15328_1 1160707.AJIK01000037_gene1777 4.32e-53 173.0 COG3860@1|root,COG3860@2|Bacteria,1TPHH@1239|Firmicutes,4HCHE@91061|Bacilli,26DP4@186818|Planococcaceae 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2087) - - - - - - - - - - - - DUF2087,GerE k141_15328_2 218284.CCDN010000001_gene258 5e-26 98.2 COG3860@1|root,COG3860@2|Bacteria,1VA52@1239|Firmicutes,4HN02@91061|Bacilli,1ZIRW@1386|Bacillus 91061|Bacilli S GIY-YIG catalytic domain - - - - - - - - - - - - GIY-YIG k141_28406_1 1125863.JAFN01000001_gene808 5.38e-96 301.0 COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,42N86@68525|delta/epsilon subdivisions,2WIV4@28221|Deltaproteobacteria 28221|Deltaproteobacteria H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source nadE - 6.3.5.1 ko:K01950 ko00760,ko01100,map00760,map01100 M00115 R00257 RC00010,RC00100 ko00000,ko00001,ko00002,ko01000 - - - CN_hydrolase,NAD_synthase k141_15329_1 218284.CCDN010000006_gene3628 2.17e-113 331.0 COG1481@1|root,COG1481@2|Bacteria,1TP2X@1239|Firmicutes,4HB4H@91061|Bacilli,1ZBKY@1386|Bacillus 91061|Bacilli K May be required for sporulation whiA GO:0008150,GO:0043937,GO:0050789,GO:0050793,GO:0065007 - ko:K09762 - - - - ko00000 - - - HTH_WhiA,LAGLIDADG_WhiA,WhiA_N k141_3543_1 1341151.ASZU01000004_gene253 4.98e-15 81.3 COG4487@1|root,COG5280@1|root,COG4487@2|Bacteria,COG5280@2|Bacteria,1UHTF@1239|Firmicutes,4IT3Y@91061|Bacilli 91061|Bacilli D Tail tape measure protein, TP901 family - - - - - - - - - - - - PhageMin_Tail,SLT k141_31878_1 1178482.BJB45_05345 1.88e-65 206.0 COG1173@1|root,COG1173@2|Bacteria,1MUG0@1224|Proteobacteria,1RN08@1236|Gammaproteobacteria,1XIY8@135619|Oceanospirillales 135619|Oceanospirillales EP transporter - - - ko:K02034,ko:K12370 ko02010,ko02024,map02010,map02024 M00239,M00324 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1,OppC_N k141_31878_2 1192868.CAIU01000015_gene1923 6.62e-17 80.1 COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,2TQP0@28211|Alphaproteobacteria,43HBK@69277|Phyllobacteriaceae 28211|Alphaproteobacteria P Belongs to the ABC transporter superfamily - - - ko:K02031,ko:K02032 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - ABC_tran,oligo_HPY k141_36749_1 566466.NOR53_3413 5.48e-11 73.9 COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1T234@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Adenylate cyclase - - - - - - - - - - - - TPR_16 k141_28517_1 218284.CCDN010000002_gene2489 3.3e-122 353.0 COG3971@1|root,COG3971@2|Bacteria,1UYC8@1239|Firmicutes,4HB58@91061|Bacilli,1ZDRH@1386|Bacillus 91061|Bacilli Q COG3971 2-keto-4-pentenoate hydratase - - 4.1.1.77 ko:K01617 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 M00569 R02602,R05374 RC00751,RC02672 ko00000,ko00001,ko00002,ko01000 - - - FAA_hydrolase k141_8291_1 1219077.VAZ01S_070_00260 7.15e-96 291.0 COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,1RMZD@1236|Gammaproteobacteria,1XTSW@135623|Vibrionales 135623|Vibrionales E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine hisD GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01158,R01163,R03012 RC00099,RC00242,RC00463 ko00000,ko00001,ko00002,ko01000 - - - Histidinol_dh k141_8291_2 1280001.BAOA01000027_gene4793 1.82e-90 273.0 COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,1RP4T@1236|Gammaproteobacteria,1XTFK@135623|Vibrionales 135623|Vibrionales E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily hisC GO:0000105,GO:0003674,GO:0003824,GO:0004400,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k141_8292_2 1469245.JFBG01000044_gene1900 1.53e-05 52.0 COG0420@1|root,COG0420@2|Bacteria,1NVM4@1224|Proteobacteria 1224|Proteobacteria L Calcineurin-like phosphoesterase superfamily domain - - - - - - - - - - - - Metallophos,Metallophos_2 k141_31879_2 674977.VMC_00630 0.0 976.0 COG1012@1|root,COG1012@2|Bacteria,1MUHV@1224|Proteobacteria,1RNFN@1236|Gammaproteobacteria,1XTUN@135623|Vibrionales 135623|Vibrionales C COG1012 NAD-dependent aldehyde dehydrogenases - - 1.2.1.18,1.2.1.27 ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 M00013 R00705,R00706,R00922,R00935 RC00004,RC02723,RC02817 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_36752_1 339671.Asuc_0227 2.79e-23 102.0 COG0364@1|root,COG0364@2|Bacteria,1MUN0@1224|Proteobacteria,1RN76@1236|Gammaproteobacteria,1Y6QR@135625|Pasteurellales 135625|Pasteurellales G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone zwf - 1.1.1.363,1.1.1.49 ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 M00004,M00006,M00008 R00835,R02736,R10907 RC00001,RC00066 ko00000,ko00001,ko00002,ko01000,ko04147 - - - G6PD_C,G6PD_N k141_36752_2 99598.Cal7507_4692 5.43e-23 99.4 COG0362@1|root,COG0362@2|Bacteria,1G01J@1117|Cyanobacteria,1HJ38@1161|Nostocales 1117|Cyanobacteria G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH gnd - 1.1.1.343,1.1.1.44 ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 M00004,M00006 R01528,R10221 RC00001,RC00539 ko00000,ko00001,ko00002,ko01000 - - - 6PGD,NAD_binding_2 k141_15404_1 1116375.VEJY3_17211 1.27e-213 599.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RQ6F@1236|Gammaproteobacteria,1XUU7@135623|Vibrionales 135623|Vibrionales C belongs to the aldehyde dehydrogenase family - - - ko:K15786 ko00260,map00260 - R09805 RC00080 ko00000,ko00001,ko01000 - - - Aldedh k141_15404_2 1116375.VEJY3_17206 3.69e-187 528.0 COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,1RNW9@1236|Gammaproteobacteria,1XUZX@135623|Vibrionales 135623|Vibrionales E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - 2.6.1.76 ko:K15785 ko00260,map00260 - R06977 RC00006,RC00062 ko00000,ko00001,ko01000 - - - Aminotran_3 k141_36753_1 237368.SCABRO_01870 2.54e-65 221.0 COG0043@1|root,COG0043@2|Bacteria,2IYCA@203682|Planctomycetes 203682|Planctomycetes H COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and - - 4.1.1.98 ko:K03182 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04985,R04986 RC00391 ko00000,ko00001,ko00002,ko01000 - - - UbiD k141_31883_1 218284.CCDN010000001_gene380 1.18e-103 311.0 COG4109@1|root,COG4109@2|Bacteria,1TPU6@1239|Firmicutes,4HB62@91061|Bacilli,1ZB1Q@1386|Bacillus 91061|Bacilli K transcriptional regulator containing CBS domains ytoI - - - - - - - - - - - 4HBT,CBS,DRTGG,GntR,HTH_24 k141_30771_1 1056820.KB900640_gene299 3.7e-96 309.0 COG4447@1|root,COG4447@2|Bacteria,1MVMU@1224|Proteobacteria,1T46X@1236|Gammaproteobacteria,2PPXX@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria S CBD_II - - - - - - - - - - - - CBM_10,CBM_2 k141_36755_1 1385511.N783_15675 8.41e-52 167.0 COG0346@1|root,COG0346@2|Bacteria,1V958@1239|Firmicutes,4HK0W@91061|Bacilli,2YBWA@289201|Pontibacillus 91061|Bacilli E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - ko:K11210 - - - - ko00000,ko01000 - - - Glyoxalase k141_15405_2 1116375.VEJY3_07760 1.43e-125 379.0 COG0457@1|root,COG2199@1|root,COG0457@2|Bacteria,COG2199@2|Bacteria,1NW5T@1224|Proteobacteria,1SPKH@1236|Gammaproteobacteria,1XT8U@135623|Vibrionales 135623|Vibrionales T Tetratricopeptide repeat - - - - - - - - - - - - GGDEF,TPR_12,TPR_7,TPR_8 k141_36756_1 218284.CCDN010000005_gene3202 2.24e-48 156.0 COG0662@1|root,COG0662@2|Bacteria,1U8MW@1239|Firmicutes,4IIJV@91061|Bacilli,1ZNPR@1386|Bacillus 91061|Bacilli G Cupin 2, conserved barrel domain protein - - - - - - - - - - - - - k141_36756_2 218284.CCDN010000005_gene3201 1.21e-31 121.0 COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HA2G@91061|Bacilli,1ZBE5@1386|Bacillus 91061|Bacilli IQ Activates fatty acids by binding to coenzyme A lcfB_2 - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding,AMP-binding_C k141_8295_1 1382305.AZUC01000046_gene340 1.05e-69 214.0 COG2306@1|root,COG2306@2|Bacteria,1VTFM@1239|Firmicutes,4HURM@91061|Bacilli,26HCE@186818|Planococcaceae 91061|Bacilli S Protein of unknown function (DUF402) - - - - - - - - - - - - DUF402 k141_15406_1 1294265.JCM21738_4012 1.76e-53 169.0 2DSU9@1|root,33HF9@2|Bacteria,1VIQ9@1239|Firmicutes,4HPSB@91061|Bacilli,1ZG8K@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3397) - - - - - - - - - - - - DUF3397 k141_15406_2 1294265.JCM21738_4011 2.33e-29 111.0 COG1893@1|root,COG1893@2|Bacteria,1V1NJ@1239|Firmicutes,4HFWT@91061|Bacilli,1ZFJY@1386|Bacillus 91061|Bacilli H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid panE GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008677,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU15110 ApbA,ApbA_C k141_30773_1 1453501.JELR01000001_gene2504 1.08e-116 338.0 COG0061@1|root,COG0061@2|Bacteria,1MUBC@1224|Proteobacteria,1RP84@1236|Gammaproteobacteria,464AZ@72275|Alteromonadaceae 1236|Gammaproteobacteria H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP nadK GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 - R00104 RC00002,RC00078 ko00000,ko00001,ko01000 - - iEcSMS35_1347.EcSMS35_2767 NAD_kinase k141_28519_1 690850.Desaf_2309 4.69e-42 151.0 COG2187@1|root,COG2187@2|Bacteria,1MU9M@1224|Proteobacteria,42NEZ@68525|delta/epsilon subdivisions,2WJ5R@28221|Deltaproteobacteria,2MF8A@213115|Desulfovibrionales 28221|Deltaproteobacteria S AAA domain - - - ko:K07028 - - - - ko00000 - - - AAA_33,APH k141_28519_2 65093.PCC7418_0263 2.71e-63 203.0 COG1926@1|root,COG1926@2|Bacteria,1G2IS@1117|Cyanobacteria 1117|Cyanobacteria S PFAM Phosphoribosyl transferase domain - - - ko:K07100 - - - - ko00000 - - - Pribosyltran k141_28519_3 631454.N177_2763 1.41e-73 229.0 COG0412@1|root,COG0412@2|Bacteria,1QVEZ@1224|Proteobacteria,2TWNH@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q Dienelactone hydrolase - - - ko:K07100 - - - - ko00000 - - - Abhydrolase_1,DLH k141_28519_4 450851.PHZ_c0646 2.97e-85 263.0 COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,2TR4Y@28211|Alphaproteobacteria,2KFEU@204458|Caulobacterales 28211|Alphaproteobacteria F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) prsA - 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - Pribosyl_synth,Pribosyltran,Pribosyltran_N k141_15407_2 90814.KL370892_gene2110 9.93e-15 73.6 COG0366@1|root,COG0366@2|Bacteria,1MVKX@1224|Proteobacteria,1RMXP@1236|Gammaproteobacteria,45ZX1@72273|Thiotrichales 72273|Thiotrichales G Alpha amylase, catalytic domain - - 2.4.1.7 ko:K00690 ko00500,map00500 - R00803 RC00028 ko00000,ko00001,ko01000 - GH13 - Alpha-amylase k141_31887_1 1288826.MSNKSG1_06993 3.02e-139 407.0 COG2079@1|root,COG2079@2|Bacteria,1MUIG@1224|Proteobacteria,1RPQN@1236|Gammaproteobacteria,4660P@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein involved in propionate catabolism prpD GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019679,GO:0019752,GO:0032787,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0046459,GO:0047547,GO:0048037,GO:0051536,GO:0051537,GO:0051540,GO:0071704,GO:0072329,GO:1901575 4.2.1.79 ko:K01720 ko00640,map00640 - R04424 RC01152 ko00000,ko00001,ko01000 - - iEcolC_1368.EcolC_3291 MmgE_PrpD k141_7699_10 1279017.AQYJ01000024_gene1148 5.95e-165 476.0 COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RQTU@1236|Gammaproteobacteria,465ST@72275|Alteromonadaceae 1236|Gammaproteobacteria C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family merA - - - - - - - - - - - Pyr_redox_2,Pyr_redox_dim,SNARE_assoc k141_20781_2 1218173.BALCAV_0214500 5.32e-69 219.0 COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,1TPE2@1239|Firmicutes,4H9WH@91061|Bacilli,1ZCWN@1386|Bacillus 91061|Bacilli P Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B,Rhodanese k141_24447_1 1134474.O59_000797 5e-31 124.0 COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,1RNPZ@1236|Gammaproteobacteria,1FG4A@10|Cellvibrio 1236|Gammaproteobacteria L May be involved in recombinational repair of damaged DNA recN GO:0000724,GO:0000725,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 - ko:K03631 - - - - ko00000,ko03400 - - - AAA_23,SMC_N k141_24447_2 1380386.JIAW01000005_gene1680 2.18e-07 53.9 COG0558@1|root,COG0558@2|Bacteria,2GM3F@201174|Actinobacteria,236BF@1762|Mycobacteriaceae 201174|Actinobacteria I CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase pgsA2 GO:0003674,GO:0003824,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 - R01801,R02030 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 - - - CDP-OH_P_transf k141_37409_2 218284.CCDN010000001_gene610 1.87e-18 83.6 COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,4HBJM@91061|Bacilli,1ZAWN@1386|Bacillus 91061|Bacilli H Belongs to the folylpolyglutamate synthase family folC GO:0003674,GO:0003824,GO:0004326,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006761,GO:0006807,GO:0008150,GO:0008152,GO:0008841,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046452,GO:0046483,GO:0046900,GO:0046901,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 - - - Mur_ligase_C,Mur_ligase_M k141_25751_1 1042377.AFPJ01000007_gene1765 1.79e-50 170.0 COG1526@1|root,COG1526@2|Bacteria,1NRU0@1224|Proteobacteria,1RNFH@1236|Gammaproteobacteria,467M6@72275|Alteromonadaceae 1236|Gammaproteobacteria C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH fdhD - - ko:K02379 - - - - ko00000 - - - FdhD-NarQ k141_23357_1 218284.CCDN010000001_gene203 5.05e-78 238.0 COG0390@1|root,COG0390@2|Bacteria,1UY1N@1239|Firmicutes,4HDM4@91061|Bacilli,1ZB6C@1386|Bacillus 91061|Bacilli S transport system, permease component yjkA GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0009987,GO:0015075,GO:0016020,GO:0016021,GO:0019725,GO:0022857,GO:0030003,GO:0031224,GO:0031226,GO:0034220,GO:0042592,GO:0044425,GO:0044459,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071944,GO:0098771 - ko:K02069 - M00211 - - ko00000,ko00002,ko02000 9.B.25.1 - - UPF0014 k141_23357_2 218284.CCDN010000001_gene204 2.26e-82 248.0 COG1136@1|root,COG1136@2|Bacteria,1V3HH@1239|Firmicutes,4HHE3@91061|Bacilli,1ZE0V@1386|Bacillus 91061|Bacilli V ABC transporter - - - ko:K02068 - M00211 - - ko00000,ko00002,ko02000 - - - ABC_tran k141_14838_1 218284.CCDN010000001_gene787 6.12e-149 440.0 COG0768@1|root,COG0768@2|Bacteria,1TQHY@1239|Firmicutes,4HAFX@91061|Bacilli,1ZBJM@1386|Bacillus 91061|Bacilli M penicillin-binding protein pbpH - - ko:K21465 ko00550,map00550 - - - ko00000,ko00001,ko01011 - - - PBP_dimer,Transpeptidase k141_14838_2 1307436.PBF_21703 4.54e-07 50.8 COG0477@1|root,COG0477@2|Bacteria,1TTC8@1239|Firmicutes,4HAPZ@91061|Bacilli,1ZAQ7@1386|Bacillus 91061|Bacilli EGP Major facilitator superfamily yqgE - - ko:K08222 - - - - ko00000,ko02000 2.A.1.33 - - MFS_1 k141_5541_1 1117379.BABA_08196 5.87e-08 53.1 COG1670@1|root,COG1670@2|Bacteria,1UHTR@1239|Firmicutes,4IS9D@91061|Bacilli,1ZS3J@1386|Bacillus 91061|Bacilli J Acetyltransferase (GNAT) family - - - - - - - - - - - - Acetyltransf_1 k141_7700_1 574376.BAMA_14905 7.58e-102 300.0 COG0528@1|root,COG0528@2|Bacteria,1TPXN@1239|Firmicutes,4H9UB@91061|Bacilli,1ZBMW@1386|Bacillus 91061|Bacilli F Catalyzes the reversible phosphorylation of UMP to UDP - - 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 - R00158 RC00002 ko00000,ko00001,ko01000 - - - AA_kinase k141_24448_1 1453501.JELR01000002_gene1465 7.23e-60 191.0 COG0024@1|root,COG0024@2|Bacteria,1MU99@1224|Proteobacteria,1RMHN@1236|Gammaproteobacteria,464SS@72275|Alteromonadaceae 1236|Gammaproteobacteria E Methionine aminopeptidase map - 3.4.11.18 ko:K01265 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M24 k141_24448_2 1453501.JELR01000002_gene1465 3.87e-43 147.0 COG0024@1|root,COG0024@2|Bacteria,1MU99@1224|Proteobacteria,1RMHN@1236|Gammaproteobacteria,464SS@72275|Alteromonadaceae 1236|Gammaproteobacteria E Methionine aminopeptidase map - 3.4.11.18 ko:K01265 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M24 k141_12744_1 218284.CCDN010000004_gene3084 1.44e-113 332.0 COG0564@1|root,COG0564@2|Bacteria,1TSM6@1239|Firmicutes,4HA7M@91061|Bacilli,1ZDMG@1386|Bacillus 91061|Bacilli J Responsible for synthesis of pseudouridine from uracil rluA GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23,5.4.99.28,5.4.99.29 ko:K06177,ko:K06180 - - - - ko00000,ko01000,ko03009,ko03016 - - - PseudoU_synth_2 k141_18621_1 218284.CCDN010000001_gene220 1.2e-74 231.0 COG2962@1|root,COG2962@2|Bacteria,1TQF2@1239|Firmicutes,4HAYU@91061|Bacilli,1ZD78@1386|Bacillus 91061|Bacilli S -transporter rarD - - ko:K05786 - - - - ko00000,ko02000 2.A.7.7 - - EamA k141_18621_2 218284.CCDN010000001_gene219 1.12e-165 477.0 COG1574@1|root,COG1574@2|Bacteria,1TQ6G@1239|Firmicutes,4H9T6@91061|Bacilli,1ZBDY@1386|Bacillus 91061|Bacilli S amidohydrolase nfdA_1 - - - - - - - - - - - Amidohydro_3 k141_6642_2 218284.CCDN010000005_gene3185 5.62e-59 188.0 COG0671@1|root,COG0671@2|Bacteria,1VF2U@1239|Firmicutes,4HNXR@91061|Bacilli,1ZDET@1386|Bacillus 91061|Bacilli I Acid phosphatase homologues pgpB1 - 3.6.1.27 ko:K19302 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - PAP2 k141_16095_1 1042377.AFPJ01000042_gene1073 7.04e-27 109.0 COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,1RNCM@1236|Gammaproteobacteria,464B9@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs iorB - 1.3.99.16 ko:K07303 - - - - ko00000,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2,TAT_signal k141_16095_2 504472.Slin_5426 9.01e-74 226.0 COG2080@1|root,COG2080@2|Bacteria,4NM72@976|Bacteroidetes,47XN3@768503|Cytophagia 976|Bacteroidetes C [2Fe-2S] binding domain - - 1.3.99.16 ko:K07302 - - - - ko00000,ko01000 - - - Fer2,Fer2_2 k141_37410_1 218284.CCDN010000001_gene1002 3.41e-29 107.0 COG0835@1|root,COG0835@2|Bacteria,1V428@1239|Firmicutes,4HI77@91061|Bacilli,1ZFHY@1386|Bacillus 91061|Bacilli NT COG0835 Chemotaxis signal transduction protein - - - ko:K03408 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - CheW k141_20782_1 1385510.N781_05135 0.000397 43.5 COG1388@1|root,COG3584@1|root,COG1388@2|Bacteria,COG3584@2|Bacteria,1UV4J@1239|Firmicutes,4HCGU@91061|Bacilli,2YA9Y@289201|Pontibacillus 91061|Bacilli M Peptidoglycan-binding protein yocH_2 - - - - - - - - - - - 3D,LysM k141_31406_2 1408433.JHXV01000004_gene3473 4.56e-77 241.0 COG0693@1|root,COG0693@2|Bacteria,4NGII@976|Bacteroidetes,1HWTK@117743|Flavobacteriia 976|Bacteroidetes I intracellular protease amidase - - - - - - - - - - - - DJ-1_PfpI k141_31406_3 1121921.KB898709_gene426 1.21e-113 326.0 COG0346@1|root,COG0346@2|Bacteria,1QEI0@1224|Proteobacteria,1RRJ9@1236|Gammaproteobacteria 1236|Gammaproteobacteria E COG0346 Lactoylglutathione lyase and related lyases - - - - - - - - - - - - Glyoxalase k141_32630_1 1034347.CAHJ01000059_gene667 5.25e-10 60.8 COG0699@1|root,COG0699@2|Bacteria,1TR0Q@1239|Firmicutes,4HBAC@91061|Bacilli,1ZAXM@1386|Bacillus 91061|Bacilli S Dynamin family ypbR GO:0000910,GO:0003674,GO:0003824,GO:0003924,GO:0005575,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022402,GO:0022607,GO:0031224,GO:0032506,GO:0044085,GO:0044425,GO:0051301,GO:0071840,GO:0090529 - - - - - - - - - - Dynamin_N k141_30223_1 65093.PCC7418_0984 2.22e-12 71.6 COG0845@1|root,COG0845@2|Bacteria,1G29R@1117|Cyanobacteria 1117|Cyanobacteria M Rnd family efflux transporter mfp subunit - - - ko:K02005 - - - - ko00000 - - - Biotin_lipoyl_2,HlyD_3 k141_14839_1 218284.CCDN010000005_gene3419 1.14e-71 226.0 COG2124@1|root,COG2124@2|Bacteria,1TPWZ@1239|Firmicutes,4HAGS@91061|Bacilli,1ZC1Y@1386|Bacillus 91061|Bacilli C Cytochrome P450 cypA - - ko:K15468 - - - - ko00000,ko01008 - - - p450 k141_29131_1 1246995.AFR_26885 4.58e-06 52.0 COG1396@1|root,COG1396@2|Bacteria,2GR3F@201174|Actinobacteria 201174|Actinobacteria K transcriptional clgR - - - - - - - - - - - HTH_3,HTH_31 k141_29131_2 1283337.B0ZSI4_BPHA1 6.12e-274 793.0 4QAY9@10239|Viruses,4QUV8@35237|dsDNA viruses no RNA stage,4QPFD@28883|Caudovirales,4QIII@10662|Myoviridae 10662|Myoviridae S hydrolase activity, acting on acid anhydrides - - - - - - - - - - - - - k141_27066_1 240302.BN982_01645 4.03e-09 61.2 COG2021@1|root,COG2021@2|Bacteria 2|Bacteria E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine - - 1.11.1.10,3.1.1.24 ko:K00433,ko:K01055 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00568 R02991 RC00825 ko00000,ko00001,ko00002,ko01000 - - - Abhydrolase_1,Abhydrolase_6,Hydrolase_4 k141_33979_1 42565.FP66_07045 1.77e-236 655.0 COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,1RNQA@1236|Gammaproteobacteria,1XHYF@135619|Oceanospirillales 135619|Oceanospirillales G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis eno - 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 - - - Enolase_C,Enolase_N k141_7701_1 1279017.AQYJ01000029_gene3492 3.2e-70 217.0 COG1280@1|root,COG1280@2|Bacteria,1RDPB@1224|Proteobacteria,1S5JJ@1236|Gammaproteobacteria,4681J@72275|Alteromonadaceae 1236|Gammaproteobacteria E LysE type translocator - - - - - - - - - - - - LysE k141_17270_2 935863.AWZR01000003_gene2647 6.11e-38 151.0 COG1262@1|root,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,1S6X1@1236|Gammaproteobacteria,1X450@135614|Xanthomonadales 135614|Xanthomonadales S Sulfatase-modifying factor enzyme 1 - - - - - - - - - - - - FGE-sulfatase k141_9066_2 218284.CCDN010000005_gene3448 8.3e-38 140.0 COG1009@1|root,COG2111@1|root,COG1009@2|Bacteria,COG2111@2|Bacteria,1TQW4@1239|Firmicutes,4H9YR@91061|Bacilli,1ZAZ0@1386|Bacillus 91061|Bacilli CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit mrpA - - ko:K05565 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - DUF4040,Proton_antipo_M,Proton_antipo_N k141_6655_1 1144312.PMI09_02611 7.87e-15 75.9 COG3344@1|root,COG3344@2|Bacteria 2|Bacteria L reverse transcriptase - - - - - - - - - - - - RVT_1 k141_7719_1 1254432.SCE1572_24565 9.38e-86 270.0 COG1953@1|root,COG1953@2|Bacteria,1MV18@1224|Proteobacteria,42X2Z@68525|delta/epsilon subdivisions,2WTRX@28221|Deltaproteobacteria,2YTSH@29|Myxococcales 28221|Deltaproteobacteria FH Permease for cytosine/purines, uracil, thiamine, allantoin - - - ko:K03457 - - - - ko00000 2.A.39 - - Transp_cyt_pur k141_11504_2 218284.CCDN010000006_gene3743 2.98e-16 78.2 COG1175@1|root,COG1175@2|Bacteria,1TPMR@1239|Firmicutes,4HA5B@91061|Bacilli,1ZRMB@1386|Bacillus 91061|Bacilli G Binding-protein-dependent transport system inner membrane component lacF3 - - ko:K02025,ko:K10241 ko02010,map02010 M00206,M00207 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.23 - - BPD_transp_1 k141_30232_2 1122137.AQXF01000001_gene2572 8.8e-109 320.0 COG0823@1|root,COG0823@2|Bacteria,1N4BQ@1224|Proteobacteria 1224|Proteobacteria U WD40-like Beta Propeller Repeat - - - - - - - - - - - - PD40 k141_27094_1 1042377.AFPJ01000052_gene1581 5.21e-141 408.0 COG3712@1|root,COG3712@2|Bacteria,1MZCK@1224|Proteobacteria,1S88I@1236|Gammaproteobacteria,467V5@72275|Alteromonadaceae 1236|Gammaproteobacteria PT Domain of unknown function (DUF4880) - - - ko:K07165 - - - - ko00000 - - - DUF4880,DUF4974,FecR k141_35222_1 218284.CCDN010000008_gene4190 3.92e-71 219.0 COG1187@1|root,COG1187@2|Bacteria,1TQZ2@1239|Firmicutes,4H9VU@91061|Bacilli,1ZCAM@1386|Bacillus 91061|Bacilli J Belongs to the pseudouridine synthase RsuA family rsuA GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19 ko:K06183 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 k141_10346_1 218284.CCDN010000002_gene2837 1e-227 633.0 COG0247@1|root,COG0247@2|Bacteria,1TR46@1239|Firmicutes,4HAY9@91061|Bacilli,1ZATD@1386|Bacillus 91061|Bacilli C Glycolate oxidase glcF - - ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001 - - - CCG,Fer4_8 k141_4235_1 314230.DSM3645_03568 6.4e-52 182.0 COG0265@1|root,COG2234@1|root,COG0265@2|Bacteria,COG2234@2|Bacteria,2IX8E@203682|Planctomycetes 203682|Planctomycetes O PA domain - - - - - - - - - - - - PA,PDZ_2,Peptidase_M28 k141_2968_1 218284.CCDN010000007_gene3981 1.64e-10 64.3 2AUKD@1|root,31K93@2|Bacteria,1V6PK@1239|Firmicutes,4HI5F@91061|Bacilli,1ZEE3@1386|Bacillus 91061|Bacilli S stage II sporulation protein R spoIIR - - ko:K06387 - - - - ko00000 - - - Spore_II_R k141_7720_1 218284.CCDN010000004_gene3055 2.73e-85 261.0 COG4134@1|root,COG4134@2|Bacteria,1TR3G@1239|Firmicutes,4HAW1@91061|Bacilli,1ZD00@1386|Bacillus 91061|Bacilli S Bacterial extracellular solute-binding protein - - - ko:K02055 ko02024,map02024 M00193 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11 - - SBP_bac_8 k141_27851_1 1116375.VEJY3_19861 1.01e-38 136.0 COG0583@1|root,COG0583@2|Bacteria,1MZTA@1224|Proteobacteria,1RN7R@1236|Gammaproteobacteria,1XSKB@135623|Vibrionales 135623|Vibrionales K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_27851_2 1116375.VEJY3_19856 6.48e-199 575.0 COG1042@1|root,COG1247@1|root,COG1042@2|Bacteria,COG1247@2|Bacteria,1MW98@1224|Proteobacteria,1RPXX@1236|Gammaproteobacteria,1XTRU@135623|Vibrionales 135623|Vibrionales CM COG1042 Acyl-CoA synthetase (NDP forming) yfiQ - - ko:K09181 - - - - ko00000 - - - ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig k141_16110_1 1453501.JELR01000001_gene2637 9.47e-132 385.0 COG3106@1|root,COG3106@2|Bacteria,1MX6E@1224|Proteobacteria,1RQ05@1236|Gammaproteobacteria,464CF@72275|Alteromonadaceae 1236|Gammaproteobacteria S YcjX-like family, DUF463 ycjX - - ko:K06918 - - - - ko00000 - - - DUF463 k141_17271_1 501479.ACNW01000056_gene4237 6.24e-111 329.0 COG0624@1|root,COG0624@2|Bacteria,1MVBR@1224|Proteobacteria,2TUHU@28211|Alphaproteobacteria 28211|Alphaproteobacteria E dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is dapE2 - 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20 k141_22047_1 1453501.JELR01000001_gene2508 0.0 1035.0 28IUR@1|root,2Z8TE@2|Bacteria,1NW7C@1224|Proteobacteria,1RP4W@1236|Gammaproteobacteria,465G0@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_1751_1 397278.JOJN01000015_gene3489 4.61e-19 86.7 COG1028@1|root,COG1028@2|Bacteria,2GJU1@201174|Actinobacteria,4DNSY@85009|Propionibacteriales 201174|Actinobacteria IQ KR domain - - 1.1.1.69 ko:K00046 - - - - ko00000,ko01000 - - - adh_short_C2 k141_1751_2 1453496.AT03_06005 7.01e-05 44.7 COG1024@1|root,COG1024@2|Bacteria,1MVQN@1224|Proteobacteria,1RPE2@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Enoyl-CoA hydratase paaG GO:0003674,GO:0003824,GO:0004300,GO:0005488,GO:0005515,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0019395,GO:0019439,GO:0019748,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575 5.3.3.18 ko:K15866 ko00360,ko01120,map00360,map01120 - R09837,R09839 RC00004,RC00326,RC02689,RC03003 ko00000,ko00001,ko01000 - - iECO103_1326.ECO103_1531,iJN746.PP_3283,iYL1228.KPN_01475 ECH_1 k141_27095_1 218284.CCDN010000009_gene4318 2.4e-14 70.5 COG1028@1|root,COG1028@2|Bacteria,1V1Z9@1239|Firmicutes,4HCPI@91061|Bacilli,1ZFQF@1386|Bacillus 91061|Bacilli IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) yueD - 1.1.1.320 ko:K16216 - - - - ko00000,ko01000 - - - adh_short k141_27095_2 218284.CCDN010000009_gene4317 1.6e-91 272.0 COG2861@1|root,COG2861@2|Bacteria,1V413@1239|Firmicutes,4HCXZ@91061|Bacilli,1ZEQY@1386|Bacillus 91061|Bacilli S protein conserved in bacteria yibQ - - ko:K09798 - - - - ko00000 - - - Polysacc_deac_2 k141_6657_1 218284.CCDN010000001_gene1614 8.44e-24 96.7 COG0842@1|root,COG0842@2|Bacteria,1TRF1@1239|Firmicutes,4HI50@91061|Bacilli,1ZQEK@1386|Bacillus 91061|Bacilli V ABC-2 type transporter - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane,ABC2_membrane_3 k141_19732_3 1121934.AUDX01000008_gene2402 1.43e-07 49.7 2DMIE@1|root,32RSG@2|Bacteria,2IQCG@201174|Actinobacteria,4FPDC@85023|Microbacteriaceae 201174|Actinobacteria K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA whiB GO:0000302,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0010035,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0015035,GO:0015036,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042221,GO:0042493,GO:0045892,GO:0045934,GO:0047134,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0060255,GO:0065007,GO:0071731,GO:0080090,GO:0097159,GO:0097366,GO:1901363,GO:1901698,GO:1901700,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K18955 - - - - ko00000,ko03000 - - - Whib k141_29145_2 1279017.AQYJ01000029_gene3491 1.67e-44 146.0 COG3141@1|root,COG3141@2|Bacteria,1N26M@1224|Proteobacteria,1SCRN@1236|Gammaproteobacteria,468R9@72275|Alteromonadaceae 1236|Gammaproteobacteria S YebG protein - - - ko:K09918 - - - - ko00000 - - - YebG k141_11506_1 218284.CCDN010000009_gene4315 7.93e-71 233.0 COG0601@1|root,COG1173@1|root,COG0601@2|Bacteria,COG1173@2|Bacteria,1V21B@1239|Firmicutes,4HDPU@91061|Bacilli,1ZEQ7@1386|Bacillus 91061|Bacilli EP Binding-protein-dependent transport system inner membrane component - - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1,Peptidase_M1 k141_23393_1 218284.CCDN010000001_gene148 2.04e-108 321.0 COG2070@1|root,COG2070@2|Bacteria,1TPC3@1239|Firmicutes,4H9T0@91061|Bacilli,1ZBRG@1386|Bacillus 91061|Bacilli S COG2070 Dioxygenases related to 2-nitropropane dioxygenase - - 1.3.1.9 ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00083 R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765 RC00052,RC00076 ko00000,ko00001,ko00002,ko01000,ko01004 - - - NMO k141_810_1 1408303.JNJJ01000114_gene760 2.56e-65 202.0 COG3544@1|root,COG3544@2|Bacteria,1V3SJ@1239|Firmicutes,4HHS0@91061|Bacilli,1ZGTU@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF305) - - - - - - - - - - - - DUF305 k141_2969_1 435908.IDSA_01295 2.88e-34 135.0 COG1629@1|root,COG4206@1|root,COG4206@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria,2QFDI@267893|Idiomarinaceae 1236|Gammaproteobacteria M TonB-dependent Receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_5568_2 218284.CCDN010000007_gene3807 2.33e-57 178.0 COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,4HKHD@91061|Bacilli,1ZGZ0@1386|Bacillus 91061|Bacilli J Binds together with S18 to 16S ribosomal RNA rpsF GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - ko:K02990 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S6 k141_17272_1 1230343.CANP01000008_gene706 1.08e-71 229.0 COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,1RNID@1236|Gammaproteobacteria,1JC4E@118969|Legionellales 118969|Legionellales M Mycolic acid cyclopropane synthetase cfa - 2.1.1.79 ko:K00574 - - - - ko00000,ko01000 - - - CMAS k141_33992_1 1279017.AQYJ01000020_gene1214 2.11e-198 578.0 COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,1RNHV@1236|Gammaproteobacteria,46410@72275|Alteromonadaceae 1236|Gammaproteobacteria M Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) mrcB GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008289,GO:0008360,GO:0008658,GO:0008955,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031406,GO:0031975,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042277,GO:0042546,GO:0042597,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071723,GO:0071840,GO:0071944,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 2.4.1.129,3.4.16.4 ko:K05365 ko00550,map00550 - R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 iECIAI39_1322.ECIAI39_0153,iSBO_1134.SBO_0138,iSbBS512_1146.SbBS512_E0140,iYL1228.KPN_00164 PBP1_TM,Transgly,Transpeptidase,UB2H k141_33992_2 765910.MARPU_03015 1.56e-56 178.0 COG1733@1|root,COG1733@2|Bacteria,1MZ6G@1224|Proteobacteria,1S941@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator - - - - - - - - - - - - HxlR k141_33992_3 550540.Fbal_0568 3.68e-91 272.0 COG2249@1|root,COG2249@2|Bacteria,1MWV9@1224|Proteobacteria,1RQ16@1236|Gammaproteobacteria 1236|Gammaproteobacteria S modulator of drug activity B - - - ko:K03923 - - - - ko00000 - - - Flavodoxin_2 k141_33992_4 550540.Fbal_0567 4.79e-79 240.0 COG1225@1|root,COG1225@2|Bacteria,1RA5K@1224|Proteobacteria,1S28Q@1236|Gammaproteobacteria 1236|Gammaproteobacteria O alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - - - - - - - - - - AhpC-TSA,Redoxin k141_33992_6 381666.H16_A2786 1.9e-23 95.1 COG3686@1|root,COG3686@2|Bacteria,1N8EA@1224|Proteobacteria,2VSWW@28216|Betaproteobacteria,1KDHP@119060|Burkholderiaceae 28216|Betaproteobacteria S MAPEG family - - - - - - - - - - - - MAPEG k141_33992_7 493475.GARC_3588 1.36e-11 64.3 COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,1RM7N@1236|Gammaproteobacteria,463YV@72275|Alteromonadaceae 1236|Gammaproteobacteria H Glutamate-1-semialdehyde aminotransferase hemL GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016853,GO:0016866,GO:0016869,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042286,GO:0042440,GO:0042802,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 5.4.3.8 ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02272 RC00677 ko00000,ko00001,ko00002,ko01000,ko01007 - - iUMNK88_1353.UMNK88_158 Aminotran_3 k141_27096_2 218284.CCDN010000006_gene3600 2.1e-39 131.0 COG2608@1|root,COG2608@2|Bacteria,1VK5F@1239|Firmicutes,4HRF1@91061|Bacilli 91061|Bacilli P Heavy-metal-associated domain copZ - - ko:K07213 ko04978,map04978 - - - ko00000,ko00001 - - - HMA k141_24464_1 1196031.ALEG01000039_gene1211 2.34e-36 136.0 29H5Q@1|root,30439@2|Bacteria,1V63Q@1239|Firmicutes,4HHR2@91061|Bacilli,1ZE9T@1386|Bacillus 91061|Bacilli S Nuclease-related domain - - - - - - - - - - - - NERD k141_27853_1 218284.CCDN010000001_gene1807 7.6e-51 180.0 COG0323@1|root,COG0323@2|Bacteria,1TPGK@1239|Firmicutes,4HB34@91061|Bacilli,1ZB9X@1386|Bacillus 91061|Bacilli L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex mutL GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032300,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1990391 - ko:K03572 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - DNA_mis_repair,HATPase_c_3,MutL_C k141_12764_2 1131730.BAVI_22658 1.74e-186 530.0 COG3182@1|root,COG3182@2|Bacteria,1TSD4@1239|Firmicutes,4HDAS@91061|Bacilli,1ZCZS@1386|Bacillus 91061|Bacilli S PepSY-associated TM region - - - - - - - - - - - - PepSY,PepSY_TM k141_18649_1 945550.VISI1226_01390 3.25e-183 512.0 COG0176@1|root,COG0176@2|Bacteria,1MWQ8@1224|Proteobacteria,1RMS0@1236|Gammaproteobacteria,1XSNT@135623|Vibrionales 135623|Vibrionales F Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway tal GO:0003674,GO:0003824,GO:0004801,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009987,GO:0016740,GO:0016744,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 2.2.1.2 ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01827 RC00439,RC00604 ko00000,ko00001,ko00002,ko01000 - - - TAL_FSA k141_5569_1 1385511.N783_16885 1.22e-70 220.0 COG0346@1|root,COG0346@2|Bacteria,1V9DI@1239|Firmicutes,4HJGV@91061|Bacilli,2YBHT@289201|Pontibacillus 91061|Bacilli E lactoylglutathione lyase activity - - - - - - - - - - - - - k141_32653_1 218284.CCDN010000002_gene2158 2.52e-87 267.0 COG1653@1|root,COG1653@2|Bacteria,1TQ0V@1239|Firmicutes,4HA7Z@91061|Bacilli,1ZF6A@1386|Bacillus 91061|Bacilli G ABC transporter substrate-binding protein - - - - - - - - - - - - SBP_bac_1,SBP_bac_8 k141_29416_1 218284.CCDN010000002_gene2250 3.77e-113 352.0 COG2273@1|root,COG2273@2|Bacteria,1TR5U@1239|Firmicutes,4HACU@91061|Bacilli,1ZR43@1386|Bacillus 91061|Bacilli G Glycosyl hydrolases family 16 bglA3 - 3.2.1.18 ko:K01186 ko00511,ko00600,ko04142,map00511,map00600,map04142 - R04018 RC00028,RC00077 ko00000,ko00001,ko01000,ko02042 - GH33 - CBM_4_9,Glyco_hydro_16,RicinB_lectin_2 k141_20009_1 218284.CCDN010000001_gene1224 8.29e-93 282.0 28MSG@1|root,2ZB0U@2|Bacteria,1TT1H@1239|Firmicutes,4HBNQ@91061|Bacilli,1ZCHW@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2515) yppC - - - - - - - - - - - DUF2515 k141_20009_2 218284.CCDN010000001_gene1225 1.1e-32 120.0 COG0515@1|root,COG0515@2|Bacteria,1UZEH@1239|Firmicutes,4IPW7@91061|Bacilli,1ZRE1@1386|Bacillus 91061|Bacilli KLT Protein tyrosine kinase - - 2.7.11.1 ko:K08884 - - - - ko00000,ko01000,ko01001 - - - Pkinase k141_12959_2 1123073.KB899242_gene892 5.7e-28 107.0 COG1226@1|root,31669@2|Bacteria,1RIW0@1224|Proteobacteria,1S6HC@1236|Gammaproteobacteria,1X7X2@135614|Xanthomonadales 135614|Xanthomonadales P Ion channel - - - - - - - - - - - - Ion_trans_2 k141_12959_3 338963.Pcar_3001 4.04e-13 68.9 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MQ0@68525|delta/epsilon subdivisions,2WJ2A@28221|Deltaproteobacteria,43SE5@69541|Desulfuromonadales 28221|Deltaproteobacteria V AcrB/AcrD/AcrF family - - - - - - - - - - - - ACR_tran k141_30399_2 218284.CCDN010000005_gene3490 1.65e-50 168.0 COG0601@1|root,COG0601@2|Bacteria,1TRW4@1239|Firmicutes,4HEGZ@91061|Bacilli,1ZH5U@1386|Bacillus 91061|Bacilli EP Binding-protein-dependent transport system inner membrane component - - - ko:K02033 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 k141_37627_1 1295642.H839_06599 4.82e-41 152.0 COG3459@1|root,COG3459@2|Bacteria,1TVMK@1239|Firmicutes,4H9ZP@91061|Bacilli,1WH9I@129337|Geobacillus 91061|Bacilli G Glycosyl hydrolase 36 superfamily, catalytic domain chvB1 - 2.4.1.20,2.4.1.333 ko:K00702,ko:K13688,ko:K21298 ko00500,ko01100,map00500,map01100 - R00952 RC00049 ko00000,ko00001,ko01000,ko01003 - GH94,GT36,GT84 - Glyco_hydro_36,Glyco_transf_36 k141_10480_1 1042377.AFPJ01000008_gene2010 9.97e-157 442.0 COG2188@1|root,COG2188@2|Bacteria,1MX3T@1224|Proteobacteria,1S0PP@1236|Gammaproteobacteria 1236|Gammaproteobacteria K COG2188 Transcriptional regulators - - - ko:K03710 - - - - ko00000,ko03000 - - - GntR,UTRA k141_1075_1 1423321.AS29_12665 2.54e-103 320.0 COG3408@1|root,COG3408@2|Bacteria,1TPX8@1239|Firmicutes,4HDVV@91061|Bacilli,1ZEXF@1386|Bacillus 91061|Bacilli G N-terminal domain of (some) glycogen debranching enzymes - - - - - - - - - - - - GDE_C,GDE_N_bis k141_16351_1 56780.SYN_00864 7.25e-68 227.0 COG0490@1|root,COG1226@1|root,COG4651@1|root,COG0490@2|Bacteria,COG1226@2|Bacteria,COG4651@2|Bacteria,1MV34@1224|Proteobacteria,42MEM@68525|delta/epsilon subdivisions,2WK23@28221|Deltaproteobacteria,2MR2A@213462|Syntrophobacterales 28221|Deltaproteobacteria P Sodium/hydrogen exchanger family - - - ko:K03455 - - - - ko00000 2.A.37 - - Na_H_Exchanger,TrkA_C,TrkA_N k141_29417_1 766499.C357_05408 3.41e-108 337.0 COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,2TR3N@28211|Alphaproteobacteria 28211|Alphaproteobacteria J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS - 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1,zf-FPG_IleRS k141_20010_1 218284.CCDN010000007_gene3945 7.53e-110 317.0 28J0N@1|root,2Z8XT@2|Bacteria,1V1UK@1239|Firmicutes,4HD4W@91061|Bacilli,1ZBQ1@1386|Bacillus 91061|Bacilli S YwhD family ywhD - - - - - - - - - - - YwhD k141_4445_2 1453501.JELR01000002_gene522 2.75e-147 426.0 COG2111@1|root,COG2111@2|Bacteria,1N1CK@1224|Proteobacteria,1RR3K@1236|Gammaproteobacteria,469GM@72275|Alteromonadaceae 1236|Gammaproteobacteria P Domain related to MnhB subunit of Na+/H+ antiporter - - - ko:K05566 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - DUF4040,MnhB k141_4445_3 1453501.JELR01000002_gene523 4.08e-52 167.0 COG1006@1|root,COG1006@2|Bacteria,1RGU1@1224|Proteobacteria,1S6BB@1236|Gammaproteobacteria,467Z5@72275|Alteromonadaceae 1236|Gammaproteobacteria P NADH-ubiquinone/plastoquinone oxidoreductase chain 4L - - - ko:K05567 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - Oxidored_q2 k141_4445_4 1042377.AFPJ01000024_gene706 1.14e-43 155.0 COG0651@1|root,COG0651@2|Bacteria,1MURB@1224|Proteobacteria,1RQBG@1236|Gammaproteobacteria,465QH@72275|Alteromonadaceae 1236|Gammaproteobacteria CP COG0651 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit - - - ko:K05568 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - Proton_antipo_M k141_31575_2 1382303.JPOM01000001_gene779 1.2e-100 309.0 COG0438@1|root,COG0438@2|Bacteria,1MWSZ@1224|Proteobacteria,2TQQK@28211|Alphaproteobacteria,2KGQB@204458|Caulobacterales 204458|Caulobacterales M PFAM glycosyl transferase group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 k141_31575_3 1042377.AFPJ01000024_gene779 2.75e-105 315.0 COG3660@1|root,COG3660@2|Bacteria,1RC47@1224|Proteobacteria,1S53F@1236|Gammaproteobacteria,469PG@72275|Alteromonadaceae 1236|Gammaproteobacteria M Mitochondrial fission ELM1 - - - ko:K07276 - - - - ko00000 - - - Mito_fiss_Elm1 k141_31575_4 1453501.JELR01000002_gene629 1.02e-172 491.0 COG4641@1|root,COG4641@2|Bacteria,1RD4C@1224|Proteobacteria,1RYDA@1236|Gammaproteobacteria,46A53@72275|Alteromonadaceae 1236|Gammaproteobacteria S Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_trans_1_2 k141_31575_6 1279017.AQYJ01000028_gene2199 8.1e-274 754.0 COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,1RMVW@1236|Gammaproteobacteria,464Z7@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the UDP-glucose GDP-mannose dehydrogenase family ugd - 1.1.1.22 ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 M00014,M00129,M00361,M00362 R00286 RC00291 ko00000,ko00001,ko00002,ko01000 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N k141_17441_1 1294265.JCM21738_1009 1.95e-32 112.0 COG4876@1|root,COG4876@2|Bacteria,1V4YD@1239|Firmicutes,4HM8N@91061|Bacilli,1ZH18@1386|Bacillus 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2188) - - - - - - - - - - - - DUF2188 k141_17441_2 1294265.JCM21738_1010 6.48e-57 184.0 COG0523@1|root,COG0523@2|Bacteria,1TPCG@1239|Firmicutes,4HFQ5@91061|Bacilli,1ZBXA@1386|Bacillus 91061|Bacilli S cobalamin synthesis protein P47K - - - - - - - - - - - - CobW_C,cobW k141_2002_1 1294265.JCM21738_3103 4.12e-34 119.0 COG1309@1|root,COG1309@2|Bacteria,1VDNV@1239|Firmicutes,4HKG8@91061|Bacilli,1ZI66@1386|Bacillus 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - TetR_C_6,TetR_N k141_2002_2 1294265.JCM21738_3102 5.83e-104 303.0 COG0477@1|root,COG2814@2|Bacteria,1VYQ7@1239|Firmicutes,4HYZJ@91061|Bacilli,1ZFVK@1386|Bacillus 91061|Bacilli EGP Major facilitator superfamily yfiS - - - - - - - - - - - MFS_1 k141_28074_1 1274524.BSONL12_04614 1.12e-89 279.0 COG5362@1|root,COG5410@1|root,COG5362@2|Bacteria,COG5410@2|Bacteria,1TSQB@1239|Firmicutes,4HEZU@91061|Bacilli,1ZBBB@1386|Bacillus 91061|Bacilli S TIGRFAM Phage - - - - - - - - - - - - Terminase_6C k141_12985_1 218284.CCDN010000011_gene4422 1.01e-19 87.0 COG1721@1|root,COG1721@2|Bacteria,1TUWF@1239|Firmicutes,4HDRE@91061|Bacilli,1ZCAS@1386|Bacillus 91061|Bacilli S conserved protein (some members contain a von Willebrand factor type A (vWA) domain) yeaD - - - - - - - - - - - DUF58 k141_12985_2 218284.CCDN010000011_gene4423 2.24e-61 207.0 COG1305@1|root,COG1305@2|Bacteria,1TP8K@1239|Firmicutes,4HB2E@91061|Bacilli,1ZBUN@1386|Bacillus 91061|Bacilli E COG1305 Transglutaminase-like enzymes yebA - - - - - - - - - - - DUF4129,Transglut_core k141_37656_1 218284.CCDN010000001_gene95 2.92e-79 236.0 2DSU9@1|root,33HF9@2|Bacteria,1VIQ9@1239|Firmicutes,4HPSB@91061|Bacilli,1ZG8K@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3397) - - - - - - - - - - - - DUF3397 k141_17442_1 1453501.JELR01000001_gene1811 1.37e-62 209.0 COG4325@1|root,COG4325@2|Bacteria,1MXTM@1224|Proteobacteria,1RNYZ@1236|Gammaproteobacteria,466NZ@72275|Alteromonadaceae 1236|Gammaproteobacteria S Predicted membrane protein (DUF2254) - - - - - - - - - - - - DUF2254 k141_22473_1 1279017.AQYJ01000025_gene618 1.63e-83 255.0 COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,1RMMW@1236|Gammaproteobacteria,466D8@72275|Alteromonadaceae 1236|Gammaproteobacteria M Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) lpxK GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008654,GO:0009029,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019637,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0046401,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.7.1.130 ko:K00912 ko00540,ko01100,map00540,map01100 M00060 R04657 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 - - iBWG_1329.BWG_0767,iECDH10B_1368.ECDH10B_0985,iPC815.YPO1396 LpxK k141_22473_2 1279017.AQYJ01000025_gene617 1.29e-135 389.0 COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,1RMAE@1236|Gammaproteobacteria,464GE@72275|Alteromonadaceae 1236|Gammaproteobacteria M Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria kdsB GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005996,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008690,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019294,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046394,GO:0046400,GO:0046401,GO:0046872,GO:0070567,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.7.38 ko:K00979 ko00540,ko01100,map00540,map01100 M00063 R03351,R11396 RC00152,RC00910 ko00000,ko00001,ko00002,ko01000,ko01005 - - iAF1260.b0918,iB21_1397.B21_00929,iBWG_1329.BWG_0770,iECBD_1354.ECBD_2677,iECB_1328.ECB_00922,iECDH10B_1368.ECDH10B_0988,iECDH1ME8569_1439.ECDH1ME8569_0869,iECD_1391.ECD_00922,iETEC_1333.ETEC_0986,iEcDH1_1363.EcDH1_2725,iEcHS_1320.EcHS_A1025,iEcolC_1368.EcolC_2678,iJO1366.b0918,iJR904.b0918,iPC815.YPO1400,iUMNK88_1353.UMNK88_1071,iY75_1357.Y75_RS04770 CTP_transf_3 k141_22473_3 1280674.AUJK01000007_gene697 2.78e-08 57.0 COG0812@1|root,COG0812@2|Bacteria,4NE78@976|Bacteroidetes,2FN91@200643|Bacteroidia 976|Bacteroidetes M Cell wall formation murB - 1.3.1.98 ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R03191,R03192 RC02639 ko00000,ko00001,ko01000,ko01011 - - - FAD_binding_4,MurB_C k141_16389_1 218284.CCDN010000002_gene2231 3.9e-100 298.0 COG4106@1|root,COG4106@2|Bacteria,1TRDY@1239|Firmicutes,4HEFZ@91061|Bacilli,1ZCF7@1386|Bacillus 91061|Bacilli S O-methyltransferase - - - - - - - - - - - - Methyltransf_12,Methyltransf_25,Methyltransf_31 k141_26079_1 1307436.PBF_02470 3.35e-87 265.0 2DB72@1|root,2Z7JI@2|Bacteria,1UR4B@1239|Firmicutes,4HCE4@91061|Bacilli,1ZC8T@1386|Bacillus 91061|Bacilli S Putative amidase domain yhbB - - - - - - - - - - - Amidase_6 k141_28075_1 536232.CLM_1547 7.65e-12 69.7 COG1388@1|root,COG2866@1|root,COG3409@1|root,COG1388@2|Bacteria,COG2866@2|Bacteria,COG3409@2|Bacteria,1TP3K@1239|Firmicutes,249MT@186801|Clostridia,36H9C@31979|Clostridiaceae 186801|Clostridia EM Zn_pept - - 3.4.19.11 ko:K01308 - - - - ko00000,ko01000,ko01002 - - - LysM,PG_binding_1,Peptidase_M14 k141_9454_2 223926.28808176 4.21e-81 246.0 COG0363@1|root,COG0363@2|Bacteria,1MVEA@1224|Proteobacteria,1RQ2V@1236|Gammaproteobacteria,1XV23@135623|Vibrionales 135623|Vibrionales G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion nagB - 3.5.99.6 ko:K02564 ko00520,ko01100,map00520,map01100 - R00765 RC00163 ko00000,ko00001,ko01000 - - - Glucosamine_iso k141_7093_1 218284.CCDN010000001_gene536 1.07e-114 342.0 COG3611@1|root,COG3611@2|Bacteria,1TSBB@1239|Firmicutes,4H9RI@91061|Bacilli,1ZBJY@1386|Bacillus 91061|Bacilli L Membrane attachment protein dnaB - - ko:K03346 - - - - ko00000,ko03032 - - - DnaB_2 k141_21015_1 218284.CCDN010000001_gene1740 3.76e-93 281.0 28I0M@1|root,2Z85B@2|Bacteria,1TTBC@1239|Firmicutes,4HENN@91061|Bacilli,1ZCDZ@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3231) - - - - - - - - - - - - DUF3231 k141_11838_1 1453501.JELR01000002_gene1395 2.58e-99 309.0 COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,COG3706@2|Bacteria,1PJCA@1224|Proteobacteria,1RS4H@1236|Gammaproteobacteria,4663N@72275|Alteromonadaceae 1236|Gammaproteobacteria T Putative diguanylate phosphodiesterase - - - ko:K21025 ko02025,map02025 - - - ko00000,ko00001 - - - EAL,GGDEF,PAS,PAS_8,PAS_9,Response_reg k141_17443_2 656519.Halsa_0472 6.69e-52 175.0 COG1186@1|root,COG1186@2|Bacteria,1TPSB@1239|Firmicutes,247KU@186801|Clostridia,3WACX@53433|Halanaerobiales 186801|Clostridia J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA prfB - - ko:K02836 - - - - ko00000,ko03012 - - - PCRF,RF-1 k141_24769_1 1121920.AUAU01000007_gene537 1.64e-29 110.0 COG1327@1|root,COG1327@2|Bacteria,3Y4GA@57723|Acidobacteria 57723|Acidobacteria K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes nrdR - - ko:K07738 - - - - ko00000,ko03000 - - - ATP-cone k141_24769_2 404589.Anae109_3115 8.97e-14 75.5 COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,42T19@68525|delta/epsilon subdivisions,2WQ0M@28221|Deltaproteobacteria 28221|Deltaproteobacteria D Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - - - - - - - - - - TPR_16,TPR_6 k141_22474_2 1042377.AFPJ01000030_gene450 7.63e-29 104.0 COG2921@1|root,COG2921@2|Bacteria,1PJDV@1224|Proteobacteria,1SXYT@1236|Gammaproteobacteria,468E1@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the UPF0250 family - - - ko:K09158 - - - - ko00000 - - - DUF493 k141_31576_1 1453501.JELR01000005_gene1790 1.09e-121 358.0 COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,1RQJ9@1236|Gammaproteobacteria,4656M@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K03585 ko01501,ko01503,map01501,map01503 M00646,M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,8.A.1.6 - - HlyD_D23 k141_1096_2 1219076.N646_0194 6.92e-110 317.0 COG3012@1|root,COG3012@2|Bacteria,1MZZK@1224|Proteobacteria,1S9FV@1236|Gammaproteobacteria,1XW8P@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria - - - ko:K09858 - - - - ko00000 - - - SEC-C k141_1096_3 1116375.VEJY3_05590 1.57e-146 413.0 COG0139@1|root,COG0140@1|root,COG0139@2|Bacteria,COG0140@2|Bacteria,1MW67@1224|Proteobacteria,1RMV4@1236|Gammaproteobacteria,1XT5G@135623|Vibrionales 135623|Vibrionales E Histidine biosynthesis bifunctional protein HisIE hisI GO:0000105,GO:0003674,GO:0003824,GO:0004635,GO:0004636,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.4.19,3.6.1.31 ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035,R04037 RC00002,RC01055 ko00000,ko00001,ko00002,ko01000 - - - PRA-CH,PRA-PH k141_1096_4 1280001.BAOA01000027_gene4789 1.85e-109 319.0 COG0107@1|root,COG0107@2|Bacteria,1MUS0@1224|Proteobacteria,1RPJQ@1236|Gammaproteobacteria,1XT21@135623|Vibrionales 135623|Vibrionales E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit hisF GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - - His_biosynth k141_29466_1 1123366.TH3_02490 7.17e-106 336.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria,2JPMJ@204441|Rhodospirillales 204441|Rhodospirillales V COG0841 Cation multidrug efflux pump - - - ko:K18902,ko:K19594 - M00698,M00768,M00769 - - ko00000,ko00002,ko01504,ko02000 2.A.6.2,2.A.6.2.25,2.A.6.2.34 - - ACR_tran k141_17444_1 218284.CCDN010000002_gene2004 1.18e-81 251.0 COG0002@1|root,COG0002@2|Bacteria,1TPVI@1239|Firmicutes,4H9YD@91061|Bacilli,1ZBHP@1386|Bacillus 91061|Bacilli E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde argC GO:0003674,GO:0003824,GO:0003942,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.38 ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R03443 RC00684 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU11190 Semialdhyde_dh,Semialdhyde_dhC k141_4448_1 1385511.N783_10580 7.5e-91 282.0 COG2812@1|root,COG2812@2|Bacteria,1TPS9@1239|Firmicutes,4HAUE@91061|Bacilli,2Y91N@289201|Pontibacillus 91061|Bacilli L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity dnaX GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNA_pol3_gamma3 k141_2004_1 397945.Aave_2248 1.29e-125 374.0 COG0129@1|root,COG0129@2|Bacteria,1MV4I@1224|Proteobacteria,2VKKY@28216|Betaproteobacteria,4AAUE@80864|Comamonadaceae 28216|Betaproteobacteria EG Belongs to the IlvD Edd family - - 4.2.1.25 ko:K13875 ko00053,ko01100,map00053,map01100 - R02522 RC00543 ko00000,ko00001,ko01000 - - - ILVD_EDD k141_28076_1 218284.CCDN010000001_gene102 3.98e-06 47.8 COG1024@1|root,COG1024@2|Bacteria,1UZHP@1239|Firmicutes,4HEEK@91061|Bacilli,1ZB0V@1386|Bacillus 91061|Bacilli I COG1024 Enoyl-CoA hydratase carnithine racemase - - - - - - - - - - - - ECH_1 k141_28076_2 218284.CCDN010000001_gene101 4.78e-56 181.0 2C8MW@1|root,305IT@2|Bacteria,1V5HI@1239|Firmicutes,4HGP6@91061|Bacilli,1ZBX1@1386|Bacillus 91061|Bacilli S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains ylbO - - ko:K06314 - - - - ko00000,ko03000 - - - Myb_DNA-bind_6 k141_11839_1 796606.BMMGA3_12975 1.12e-115 349.0 COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,4HABZ@91061|Bacilli,1ZB5W@1386|Bacillus 91061|Bacilli J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) thrS GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD k141_12986_1 1196031.ALEG01000011_gene5224 2.75e-82 246.0 COG4732@1|root,COG4732@2|Bacteria,1V6HH@1239|Firmicutes,4HHG6@91061|Bacilli,1ZFS2@1386|Bacillus 91061|Bacilli S Thiamine-precursor transporter protein (ThiW) thiW - - - - - - - - - - - ThiW k141_26080_1 218284.CCDN010000001_gene190 2.24e-109 334.0 COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,4HA3G@91061|Bacilli,1ZAVY@1386|Bacillus 91061|Bacilli T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,PAS_4,PAS_9 k141_21016_1 218284.CCDN010000002_gene2123 5.19e-118 349.0 COG0065@1|root,COG0065@2|Bacteria,1TPE5@1239|Firmicutes,4HAWA@91061|Bacilli,1ZCF1@1386|Bacillus 91061|Bacilli E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate leuC - 4.2.1.33,4.2.1.35 ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170 RC00497,RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS10700 Aconitase k141_16391_1 1453501.JELR01000001_gene2835 1.34e-53 170.0 COG3784@1|root,COG3784@2|Bacteria,1N6R1@1224|Proteobacteria,1SC8V@1236|Gammaproteobacteria,4694V@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF1318) ydbL - - ko:K09978 - - - - ko00000 - - - DUF1318 k141_3263_1 1279017.AQYJ01000025_gene670 5.63e-107 323.0 COG3283@1|root,COG3283@2|Bacteria,1QTS3@1224|Proteobacteria,1RNAI@1236|Gammaproteobacteria,46678@72275|Alteromonadaceae 1236|Gammaproteobacteria EK Transcriptional regulator of aromatic amino acids metabolism tyrR GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008144,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K03721 - - - - ko00000,ko03000 - - - ACT,PAS,PAS_8,Sigma54_activat k141_11840_1 1423321.AS29_07220 9.74e-57 194.0 COG1874@1|root,COG1874@2|Bacteria,1TSHK@1239|Firmicutes,4HBAR@91061|Bacilli,1ZEHU@1386|Bacillus 91061|Bacilli G Glycosyl hydrolases family 35 bgaC - 3.2.1.23 ko:K01190,ko:K12308 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 - R01105,R01678,R03355,R04783,R06114 RC00049,RC00452 ko00000,ko00001,ko01000 - - - Glyco_hydro_35 k141_34256_1 218284.CCDN010000001_gene1041 4.97e-162 463.0 COG0213@1|root,COG0213@2|Bacteria,1TPCH@1239|Firmicutes,4H9NP@91061|Bacilli,1ZBI1@1386|Bacillus 91061|Bacilli F phosphorylase pdp GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464 2.4.2.2 ko:K00756 ko00240,ko01100,map00240,map01100 - R01570,R01876,R02296,R02484 RC00063 ko00000,ko00001,ko01000 - - - Glycos_trans_3N,Glycos_transf_3,PYNP_C k141_20053_1 1323663.AROI01000024_gene1548 3.62e-65 213.0 COG0277@1|root,COG0277@2|Bacteria,1MUKV@1224|Proteobacteria,1RSF4@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Fad linked oxidase - - - - - - - - - - - - FAD_binding_4 k141_17446_1 1294265.JCM21738_2431 2.85e-138 401.0 COG3428@1|root,COG3428@2|Bacteria,1TSRJ@1239|Firmicutes,4HB8P@91061|Bacilli,1ZBIF@1386|Bacillus 91061|Bacilli S Membrane ydbT - - ko:K08981 - - - - ko00000 - - - bPH_2 k141_16392_1 218284.CCDN010000002_gene2731 8.28e-95 295.0 COG3711@1|root,COG3711@2|Bacteria,1TQT1@1239|Firmicutes,4HABH@91061|Bacilli,1ZBYI@1386|Bacillus 91061|Bacilli K transcriptional regulator, MtlR mtlR - - ko:K03483 - - - - ko00000,ko03000 - - - HTH_11,Mga,PRD,PTS_EIIA_2,PTS_IIB k141_26081_1 218284.CCDN010000001_gene781 1.18e-84 262.0 COG0477@1|root,COG2814@2|Bacteria,1TQEW@1239|Firmicutes,4HASU@91061|Bacilli,1ZE6N@1386|Bacillus 91061|Bacilli EGP Sugar (and other) transporter - - - ko:K08221 - - - - ko00000,ko02000 2.A.1.32 - - MFS_1 k141_7095_1 218284.CCDN010000006_gene3716 6.54e-44 144.0 COG0346@1|root,COG0346@2|Bacteria,1V6XU@1239|Firmicutes,4HIFI@91061|Bacilli,1ZHFW@1386|Bacillus 91061|Bacilli E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily ywkD - - ko:K08234 - - - - ko00000 - - - Glyoxalase k141_7095_2 218284.CCDN010000006_gene3717 4.93e-110 323.0 COG1227@1|root,COG1227@2|Bacteria,1TPH6@1239|Firmicutes,4H9T8@91061|Bacilli,1ZBEH@1386|Bacillus 91061|Bacilli C Inorganic pyrophosphatase ppaC GO:0003674,GO:0003824,GO:0004427,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0044237,GO:0044424,GO:0044464 3.6.1.1 ko:K15986 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - DHH,DHHA2 k141_31577_1 1453501.JELR01000002_gene826 3.08e-198 557.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,1RNAM@1236|Gammaproteobacteria,4658T@72275|Alteromonadaceae 1236|Gammaproteobacteria G COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - - - - - - - - - - DctM k141_20054_1 1479235.KK366039_gene2988 7.56e-109 314.0 COG3000@1|root,COG3000@2|Bacteria,1RJ68@1224|Proteobacteria 1224|Proteobacteria I hydroxylase crtZ - 1.14.15.24 ko:K15746 ko00906,ko01100,ko01110,map00906,map01100,map01110 M00372 R07530,R07558,R07559,R07561,R07562,R07568,R07569,R07570,R07572,R07851,R09747 RC00478,RC00704,RC02629 ko00000,ko00001,ko00002,ko01000 - - - FA_hydroxylase k141_28077_2 1453501.JELR01000002_gene943 1.05e-16 78.6 COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,1RN4I@1236|Gammaproteobacteria,46412@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) aroB GO:0000166,GO:0003674,GO:0003824,GO:0003856,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0051287,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.4 ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03083 RC00847 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b3389,iBWG_1329.BWG_3080,iECDH10B_1368.ECDH10B_3564,iECDH1ME8569_1439.ECDH1ME8569_3268,iECNA114_1301.ECNA114_3486,iEcDH1_1363.EcDH1_0324,iJO1366.b3389,iJR904.b3389,iY75_1357.Y75_RS20275 DHQ_synthase k141_11841_1 1294265.JCM21738_357 2.44e-20 89.4 COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,4HA8S@91061|Bacilli,1ZBWA@1386|Bacillus 91061|Bacilli J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,IF-2,IF2_N k141_11841_2 1294265.JCM21738_356 1.07e-61 189.0 COG1358@1|root,COG1358@2|Bacteria,1VEYG@1239|Firmicutes,4HNY7@91061|Bacilli,1ZI1N@1386|Bacillus 91061|Bacilli J ribosomal protein ylxQ - - - - - - - - - - - Ribosomal_L7Ae k141_11841_3 1294265.JCM21738_355 1.68e-53 168.0 COG2740@1|root,COG2740@2|Bacteria,1VEJS@1239|Firmicutes,4HKBY@91061|Bacilli,1ZHSV@1386|Bacillus 91061|Bacilli K nucleic-acid-binding protein implicated in transcription termination ylxR - - ko:K07742 - - - - ko00000 - - - DUF448 k141_11841_4 1294265.JCM21738_354 4.5e-49 166.0 COG0195@1|root,COG0195@2|Bacteria,1TPB3@1239|Firmicutes,4HA7F@91061|Bacilli,1ZDAH@1386|Bacillus 91061|Bacilli K Participates in both transcription termination and antitermination nusA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K02600 - - - - ko00000,ko03009,ko03021 - - - KH_5,NusA_N,S1 k141_1098_1 218284.CCDN010000001_gene1244 4.48e-118 350.0 COG0534@1|root,COG0534@2|Bacteria,1TP5U@1239|Firmicutes,4HA4W@91061|Bacilli,1ZAX6@1386|Bacillus 91061|Bacilli V Multidrug efflux pump norM GO:0003674,GO:0005215,GO:0006810,GO:0006855,GO:0008150,GO:0015238,GO:0015893,GO:0022857,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0046677,GO:0050896,GO:0051179,GO:0051234,GO:0055085 - ko:K03327 - - - - ko00000,ko02000 2.A.66.1 - - MatE k141_9457_1 42565.FP66_07635 1.69e-22 87.8 COG0851@1|root,COG0851@2|Bacteria,1N6QD@1224|Proteobacteria,1SC8W@1236|Gammaproteobacteria,1XM7J@135619|Oceanospirillales 135619|Oceanospirillales D Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell minE - - ko:K03608 - - - - ko00000,ko03036,ko04812 - - - MinE k141_9457_2 42565.FP66_07630 6.98e-79 247.0 COG2925@1|root,COG2925@2|Bacteria,1MV0U@1224|Proteobacteria,1RM85@1236|Gammaproteobacteria,1XHYI@135619|Oceanospirillales 135619|Oceanospirillales L Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates sbcB - 3.1.11.1 ko:K01141 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_X-T_C,RNase_T k141_26082_2 218284.CCDN010000006_gene3730 2.41e-64 219.0 COG2247@1|root,COG2374@1|root,COG2247@2|Bacteria,COG2374@2|Bacteria,1VKCH@1239|Firmicutes,4IS68@91061|Bacilli,1ZS2A@1386|Bacillus 91061|Bacilli M Fn3 associated XK27_02140 - - ko:K07004 - - - - ko00000 - - - CHB_HEX_C_1,Exo_endo_phos,Fn3_assoc,Gram_pos_anchor,LTD,SLH k141_24771_1 218284.CCDN010000008_gene4242 3.8e-81 253.0 COG3266@1|root,COG3266@2|Bacteria,1UYHI@1239|Firmicutes,4HFF7@91061|Bacilli,1ZE70@1386|Bacillus 91061|Bacilli S domain, Protein - - - - - - - - - - - - - k141_31578_1 550540.Fbal_0408 5.67e-14 72.8 COG3247@1|root,COG3247@2|Bacteria,1R63F@1224|Proteobacteria 1224|Proteobacteria S Short repeat of unknown function (DUF308) MA20_30435 - - - - - - - - - - - DUF308 k141_17448_1 1294265.JCM21738_27 6.37e-128 372.0 COG1686@1|root,COG1686@2|Bacteria,1TQN0@1239|Firmicutes,4HBCE@91061|Bacilli,1ZB0W@1386|Bacillus 91061|Bacilli M Belongs to the peptidase S11 family dacF GO:0003674,GO:0003824,GO:0004175,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.16.4 ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - PBP5_C,Peptidase_S11 k141_7097_1 1294265.JCM21738_2288 8.37e-133 379.0 COG1734@1|root,COG1734@2|Bacteria,1V6MF@1239|Firmicutes,4HEPK@91061|Bacilli,1ZEEI@1386|Bacillus 91061|Bacilli T COG1734 DnaK suppressor protein yteA - - - - - - - - - - - zf-dskA_traR k141_16417_1 42565.FP66_11050 3.1e-108 331.0 COG0665@1|root,COG4121@1|root,COG0665@2|Bacteria,COG4121@2|Bacteria,1MZW5@1224|Proteobacteria,1RMTE@1236|Gammaproteobacteria,1XHET@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 mnmC - 2.1.1.61 ko:K15461 - - R00601,R08702 RC00003,RC00053,RC00060,RC01483 ko00000,ko01000,ko03016 - - - DAO,Methyltransf_30 k141_4479_1 502025.Hoch_4484 1.53e-83 256.0 COG5424@1|root,COG5424@2|Bacteria,1Q9R2@1224|Proteobacteria,434J3@68525|delta/epsilon subdivisions,2X8WX@28221|Deltaproteobacteria,2Z0SN@29|Myxococcales 28221|Deltaproteobacteria H Iron-containing redox enzyme - - - - - - - - - - - - Haem_oxygenas_2 k141_4479_2 1453501.JELR01000001_gene2578 1e-119 345.0 COG4445@1|root,COG4445@2|Bacteria,1MVFE@1224|Proteobacteria,1RQ8Z@1236|Gammaproteobacteria,466MT@72275|Alteromonadaceae 1236|Gammaproteobacteria FJ COG4445 Hydroxylase for synthesis of 2-methylthio-cis-ribozeatin in tRNA miaE - - ko:K06169 - - - - ko00000,ko01000,ko03016 - - - MiaE k141_2030_1 218284.CCDN010000007_gene3968 3.26e-79 235.0 COG2204@1|root,COG2204@2|Bacteria,1V6R9@1239|Firmicutes,4HICG@91061|Bacilli,1ZQRZ@1386|Bacillus 91061|Bacilli T COG0784 FOG CheY-like receiver spo0F - - ko:K02490 ko02020,ko02024,map02020,map02024 M00485 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg k141_9484_2 1116375.VEJY3_06505 6.76e-142 402.0 COG0625@1|root,COG0625@2|Bacteria,1RA4Y@1224|Proteobacteria,1S2I8@1236|Gammaproteobacteria,1XVCI@135623|Vibrionales 135623|Vibrionales O maleylacetoacetate isomerase maiA GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006558,GO:0006559,GO:0006570,GO:0006572,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009987,GO:0016034,GO:0016054,GO:0016853,GO:0016859,GO:0017144,GO:0019439,GO:0019752,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902221,GO:1902222 5.2.1.2 ko:K01800 ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120 M00044 R03181 RC00867 ko00000,ko00001,ko00002,ko01000 - - - GST_C,GST_C_2,GST_C_3,GST_N,GST_N_3 k141_9484_3 1116375.VEJY3_06500 9.67e-249 682.0 COG0179@1|root,COG0179@2|Bacteria,1MV0V@1224|Proteobacteria,1RNYV@1236|Gammaproteobacteria,1XU6Y@135623|Vibrionales 135623|Vibrionales Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) - - 3.7.1.2 ko:K16171 ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120 M00044 R01364 RC00326,RC00446 ko00000,ko00001,ko00002,ko01000 - - - FAA_hydrolase k141_9484_4 223926.28806338 5.23e-260 712.0 COG3508@1|root,COG3508@2|Bacteria,1MV9G@1224|Proteobacteria,1RQG2@1236|Gammaproteobacteria,1XTK2@135623|Vibrionales 135623|Vibrionales Q COG3508 Homogentisate 1,2-dioxygenase - GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0055114 1.13.11.5 ko:K00451 ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120 M00044 R02519 RC00737 ko00000,ko00001,ko00002,ko01000 - - - HgmA k141_29488_1 1294265.JCM21738_436 2.19e-96 283.0 COG4314@1|root,COG4314@2|Bacteria,1V8NY@1239|Firmicutes,4HIVN@91061|Bacilli,1ZH9X@1386|Bacillus 91061|Bacilli C NosL - - - - - - - - - - - - NosL k141_19058_2 1444310.JANV01000162_gene1229 6.05e-24 102.0 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4HB97@91061|Bacilli,1ZBGZ@1386|Bacillus 91061|Bacilli C Belongs to the aldehyde dehydrogenase family ywdH - 1.2.1.3 ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_14312_1 1294265.JCM21738_1963 2.79e-135 396.0 COG0642@1|root,COG2205@2|Bacteria,1TRAB@1239|Firmicutes,4HAXE@91061|Bacilli,1ZEN9@1386|Bacillus 91061|Bacilli T Domain of unknown function (DUF4173) - - - - - - - - - - - - DUF4173 k141_8385_1 218284.CCDN010000001_gene81 1.27e-51 169.0 COG3879@1|root,COG3879@2|Bacteria,1V2J7@1239|Firmicutes,4HG14@91061|Bacilli,1ZDER@1386|Bacillus 91061|Bacilli S protein conserved in bacteria ylxX GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - - - - - - - - - - DUF881 k141_8385_2 218284.CCDN010000001_gene80 9.77e-75 224.0 COG3856@1|root,COG3856@2|Bacteria,1VA6N@1239|Firmicutes,4HIMZ@91061|Bacilli,1ZGAQ@1386|Bacillus 91061|Bacilli S small basic protein sbp - - - - - - - - - - - DUF1290 k141_34509_1 935837.JAEK01000007_gene3165 3.43e-14 67.8 COG2832@1|root,COG2832@2|Bacteria,1VEWF@1239|Firmicutes,4HHE4@91061|Bacilli,1ZQHF@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF454) - - - ko:K09790 - - - - ko00000 - - - DUF454 k141_22624_1 1453501.JELR01000002_gene332 0.0 1272.0 COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,1RNBF@1236|Gammaproteobacteria,4651T@72275|Alteromonadaceae 1236|Gammaproteobacteria J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction pnp GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 M00394 R00437,R00438,R00439,R00440 RC02795 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 - - - KH_1,PNPase,RNase_PH,RNase_PH_C,S1 k141_22624_2 1453501.JELR01000002_gene333 1.39e-52 166.0 COG0184@1|root,COG0184@2|Bacteria,1MZ2W@1224|Proteobacteria,1S8U6@1236|Gammaproteobacteria,4682T@72275|Alteromonadaceae 1236|Gammaproteobacteria J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome rpsO GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016071,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031123,GO:0031124,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02956 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S15 k141_15508_1 1121938.AUDY01000008_gene995 3.39e-36 135.0 COG0019@1|root,COG0019@2|Bacteria,1TPE9@1239|Firmicutes,4HAPF@91061|Bacilli,3ND2E@45667|Halobacillus 91061|Bacilli E Pyridoxal-dependent decarboxylase, pyridoxal binding domain - - 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS00750 Orn_Arg_deC_N,Orn_DAP_Arg_deC k141_13134_1 272943.RSP_3694 1.47e-12 65.5 COG0819@1|root,COG0819@2|Bacteria,1P18F@1224|Proteobacteria,2TWAS@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4-amino-5-aminomethyl-2-methylpyrimidine to 4-amino- 5-hydroxymethyl-2-methylpyrimidine (HMP) - - 3.5.99.2 ko:K03707 ko00730,ko01100,map00730,map01100 - R02133,R09993 RC00224,RC00652,RC02832 ko00000,ko00001,ko01000,ko03000 - - - TENA_THI-4 k141_13134_2 272943.RSP_3693 4.21e-96 286.0 COG0434@1|root,COG0434@2|Bacteria,1Q83B@1224|Proteobacteria,2U2I9@28211|Alphaproteobacteria 28211|Alphaproteobacteria S TIM-barrel enzyme - - - ko:K06971 - - - - ko00000 - - - BtpA k141_17883_1 223926.28807206 2.85e-104 312.0 COG2067@1|root,COG2067@2|Bacteria,1MUU4@1224|Proteobacteria,1RQZJ@1236|Gammaproteobacteria,1XSHP@135623|Vibrionales 135623|Vibrionales I Long-chain fatty acid transport protein - - - ko:K06076 - - - - ko00000,ko02000 1.B.9 - - Toluene_X k141_49_1 218284.CCDN010000002_gene2834 3.71e-83 251.0 COG2230@1|root,COG2230@2|Bacteria,1V4JG@1239|Firmicutes,4HH18@91061|Bacilli,1ZE3E@1386|Bacillus 91061|Bacilli M Methyltransferase - - - - - - - - - - - - CMAS,DOT1,Methyltransf_32 k141_4808_1 1307436.PBF_06506 1.59e-59 197.0 COG0477@1|root,COG2814@2|Bacteria,1VSW8@1239|Firmicutes,4HUQC@91061|Bacilli,1ZAS8@1386|Bacillus 91061|Bacilli EGP the major facilitator superfamily bmr3 - - - - - - - - - - - MFS_1 k141_5993_1 34506.g3042 4.14e-59 204.0 COG4770@1|root,KOG0238@2759|Eukaryota,38B7N@33154|Opisthokonta,3B9PR@33208|Metazoa,3D08X@33213|Bilateria,40C9Z@6231|Nematoda,1KXZF@119089|Chromadorea,40WC1@6236|Rhabditida 33208|Metazoa C propionyl-CoA carboxylase activity - - - - - - - - - - - - Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2 k141_3622_2 1453501.JELR01000001_gene2018 7.55e-98 310.0 COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,1RN05@1236|Gammaproteobacteria,464MR@72275|Alteromonadaceae 1236|Gammaproteobacteria S Insulinase (Peptidase family M16) ptrA - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C k141_28585_1 1279017.AQYJ01000022_gene2734 2.03e-186 520.0 COG0714@1|root,COG0714@2|Bacteria,1MV5I@1224|Proteobacteria,1RQ62@1236|Gammaproteobacteria,465MV@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0714 MoxR-like ATPases HA62_21050 - - - - - - - - - - - AAA,AAA_5 k141_35708_1 1279017.AQYJ01000024_gene970 2.24e-87 258.0 28R4N@1|root,2ZDIZ@2|Bacteria 2|Bacteria S Zinc-ribbon containing domain - - - - - - - - - - - - DUF1451 k141_35708_2 1453501.JELR01000001_gene2975 0.0 888.0 COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,1RP14@1236|Gammaproteobacteria,464DK@72275|Alteromonadaceae 1236|Gammaproteobacteria J Belongs to the class-I aminoacyl-tRNA synthetase family leuS GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - iECOK1_1307.ECOK1_0652,iECS88_1305.ECS88_0684,iNRG857_1313.NRG857_02925,iPC815.YPO2610 Anticodon_1,tRNA-synt_1,tRNA-synt_1_2 k141_26205_3 1329516.JPST01000014_gene668 3.03e-42 158.0 COG3941@1|root,COG5412@1|root,COG3941@2|Bacteria,COG5412@2|Bacteria,1V33U@1239|Firmicutes,4HMR7@91061|Bacilli 91061|Bacilli S tape measure - - - - - - - - - - - - - k141_34510_1 1540092.A0A0A0RVF7_9CAUD 1.92e-39 144.0 4QAX8@10239|Viruses,4QPHH@28883|Caudovirales 28883|Caudovirales S calcium ion binding - - - - - - - - - - - - - k141_30957_1 218284.CCDN010000008_gene4161 4.19e-140 400.0 COG1116@1|root,COG1116@2|Bacteria,1TRM6@1239|Firmicutes,4HBZ6@91061|Bacilli,1ZC33@1386|Bacillus 91061|Bacilli P ABC transporter ytlC - 3.6.3.36 ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 M00188,M00435,M00436 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.16,3.A.1.17,3.A.1.17.1,3.A.1.17.2,3.A.1.17.4 - - ABC_tran k141_30957_2 997296.PB1_17319 9.2e-38 135.0 COG0600@1|root,COG0600@2|Bacteria,1TR6A@1239|Firmicutes,4HARB@91061|Bacilli,1ZD96@1386|Bacillus 91061|Bacilli P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component ytlD GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02050 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - BPD_transp_1 k141_5994_1 315749.Bcer98_1836 2.03e-30 110.0 COG2755@1|root,COG2755@2|Bacteria,1V1QW@1239|Firmicutes,4HGWC@91061|Bacilli,1ZGV5@1386|Bacillus 91061|Bacilli E GDSL-like Lipase/Acylhydrolase - - - - - - - - - - - - Lipase_GDSL_2 k141_21437_1 674977.VMC_14140 2.37e-141 400.0 COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,1RN09@1236|Gammaproteobacteria,1XSI2@135623|Vibrionales 135623|Vibrionales F Essential for recycling GMP and indirectly, cGMP gmk GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_kin k141_21437_2 1205683.CAKR01000042_gene2746 1.12e-36 125.0 COG1758@1|root,COG1758@2|Bacteria,1N6TX@1224|Proteobacteria,1SCSR@1236|Gammaproteobacteria,41GCP@629|Yersinia 1236|Gammaproteobacteria K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits rpoZ GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb6 k141_21437_3 1116375.VEJY3_00740 0.0 1355.0 COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,1RN3H@1236|Gammaproteobacteria,1XSS0@135623|Vibrionales 135623|Vibrionales KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance spoT GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5,3.1.7.2 ko:K01139 ko00230,map00230 - R00336,R00429 RC00002,RC00078 ko00000,ko00001,ko01000,ko03009 - - - ACT_4,HD_4,RelA_SpoT,TGS k141_21437_4 1280001.BAOA01000051_gene1495 1.67e-149 422.0 COG0566@1|root,COG0566@2|Bacteria,1MWBE@1224|Proteobacteria,1RMPR@1236|Gammaproteobacteria,1XSPQ@135623|Vibrionales 135623|Vibrionales J Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA trmH - 2.1.1.34 ko:K00556 - - - - ko00000,ko01000,ko03016 - - - SpoU_methylas_C,SpoU_methylase k141_21437_5 1116375.VEJY3_00730 0.0 1337.0 COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,1RMMQ@1236|Gammaproteobacteria,1XUQ6@135623|Vibrionales 135623|Vibrionales L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) recG - 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecG_wedge k141_21437_6 1116375.VEJY3_00725 5.41e-143 414.0 COG2233@1|root,COG2233@2|Bacteria,1MUN9@1224|Proteobacteria,1RMGW@1236|Gammaproteobacteria,1XUCK@135623|Vibrionales 135623|Vibrionales F COG2233 Xanthine uracil permeases xanP - - ko:K16345 - - - - ko00000,ko02000 2.A.40.4.2 - - Xan_ur_permease k141_14313_1 1294265.JCM21738_1182 1.26e-25 99.4 COG1974@1|root,COG1974@2|Bacteria,1TQ3H@1239|Firmicutes,4HBHA@91061|Bacilli,1ZBMU@1386|Bacillus 91061|Bacilli K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair lexA GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 ko:K01356 - M00729 - - ko00000,ko00002,ko01000,ko01002,ko03400 - - - LexA_DNA_bind,Peptidase_S24 k141_14313_2 1294265.JCM21738_1183 8.72e-39 129.0 29S75@1|root,30DBN@2|Bacteria,1UB43@1239|Firmicutes,4IMGP@91061|Bacilli,1ZK4D@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_14313_3 1294265.JCM21738_1184 7.69e-33 125.0 COG1199@1|root,COG1199@2|Bacteria,1TRNV@1239|Firmicutes,4HBYD@91061|Bacilli,1ZARY@1386|Bacillus 91061|Bacilli KL COG1199 Rad3-related DNA helicases ypvA - 3.6.4.12 ko:K03722 - - - - ko00000,ko01000,ko03400 - - - Helicase_C_2 k141_22626_1 218284.CCDN010000001_gene1799 9.32e-120 343.0 COG2860@1|root,COG2860@2|Bacteria,1UH1K@1239|Firmicutes,4HDC7@91061|Bacilli,1ZBS1@1386|Bacillus 91061|Bacilli S membrane yvgT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - UPF0126 k141_11918_1 1453501.JELR01000001_gene3259 1.04e-69 234.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,464R3@72275|Alteromonadaceae 1236|Gammaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K18989 - M00720 - - ko00000,ko00002,ko02000 2.A.6.2.30 - - ACR_tran k141_4809_1 218284.CCDN010000001_gene1580 2.88e-102 327.0 COG0454@1|root,COG0456@2|Bacteria,1TQQA@1239|Firmicutes,4HBXN@91061|Bacilli,1ZEEE@1386|Bacillus 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10 k141_5995_1 218284.CCDN010000001_gene1555 7.27e-30 115.0 COG1011@1|root,COG1011@2|Bacteria,1V3WC@1239|Firmicutes,4HQ3B@91061|Bacilli,1ZQ6Y@1386|Bacillus 91061|Bacilli S HAD-hyrolase-like - - - ko:K07025 - - - - ko00000 - - - HAD_2 k141_24988_1 260799.BAS0455 3.63e-45 157.0 COG4722@1|root,COG4722@2|Bacteria,1VZIH@1239|Firmicutes,4I8NR@91061|Bacilli,1ZJI2@1386|Bacillus 91061|Bacilli S Phage tail protein - - - - - - - - - - - - Sipho_tail k141_24988_2 1444310.JANV01000162_gene1160 9.83e-11 70.5 2BJAU@1|root,32DKR@2|Bacteria,1UX7J@1239|Firmicutes,4IP3A@91061|Bacilli,1ZPBG@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_30958_1 997296.PB1_16594 1.21e-86 268.0 28KBQ@1|root,2Z9YP@2|Bacteria,1TT8R@1239|Firmicutes,4IRFF@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - k141_22627_1 1294265.JCM21738_2231 1.05e-118 351.0 COG3303@1|root,COG3303@2|Bacteria,1TPPW@1239|Firmicutes,4I6NR@91061|Bacilli,1ZEPE@1386|Bacillus 91061|Bacilli P Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process nrfA - 1.7.2.2 ko:K03385 ko00910,ko01120,ko05132,map00910,map01120,map05132 M00530 R05712 RC00176 ko00000,ko00001,ko00002,ko01000 - - - Cytochrom_C552 k141_20238_2 1279017.AQYJ01000023_gene3143 1.81e-106 314.0 COG2976@1|root,COG2976@2|Bacteria,1N117@1224|Proteobacteria,1S95P@1236|Gammaproteobacteria,467Y0@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria yfgM GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0009897,GO:0009986,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031233,GO:0044425,GO:0044459,GO:0044464,GO:0071575,GO:0071944,GO:0098552 - - - - - - - - - - TPR_21 k141_15511_1 223926.28807400 2.11e-144 413.0 COG1609@1|root,COG1609@2|Bacteria,1N8ZA@1224|Proteobacteria,1RSGV@1236|Gammaproteobacteria,1XSKZ@135623|Vibrionales 135623|Vibrionales K COG1609 Transcriptional regulators ebgR - - ko:K12113 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 k141_4811_1 1042377.AFPJ01000019_gene2541 2.61e-112 333.0 COG1752@1|root,COG1752@2|Bacteria,1MU6Z@1224|Proteobacteria,1RPW6@1236|Gammaproteobacteria,4669M@72275|Alteromonadaceae 1236|Gammaproteobacteria S Esterase of the alpha-beta hydrolase superfamily - - - - - - - - - - - - Patatin k141_14314_1 1294265.JCM21738_3903 4.45e-89 261.0 COG0537@1|root,COG0537@2|Bacteria,1VB6J@1239|Firmicutes,4HIE1@91061|Bacilli,1ZFUM@1386|Bacillus 91061|Bacilli FG HIT domain - - - ko:K02503 - - - - ko00000,ko04147 - - - HIT k141_28589_1 218284.CCDN010000008_gene4252 8.95e-114 336.0 COG0626@1|root,COG0626@2|Bacteria,1TPC7@1239|Firmicutes,4IS7E@91061|Bacilli,1ZS1S@1386|Bacillus 91061|Bacilli E methionine gamma-lyase megL - 4.4.1.11 ko:K01761 ko00270,ko00450,map00270,map00450 - R00654,R04770 RC00196,RC00348,RC01209,RC01210 ko00000,ko00001,ko01000 - - - Cys_Met_Meta_PP k141_23809_1 1116375.VEJY3_19856 0.0 1224.0 COG1042@1|root,COG1247@1|root,COG1042@2|Bacteria,COG1247@2|Bacteria,1MW98@1224|Proteobacteria,1RPXX@1236|Gammaproteobacteria,1XTRU@135623|Vibrionales 135623|Vibrionales CM COG1042 Acyl-CoA synthetase (NDP forming) yfiQ - - ko:K09181 - - - - ko00000 - - - ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig k141_23809_2 223926.28809186 2.75e-93 276.0 COG3266@1|root,COG3266@2|Bacteria,1QJDK@1224|Proteobacteria,1THCR@1236|Gammaproteobacteria,1XU08@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria - - - - - - - - - - - - SPOR k141_23809_3 1116375.VEJY3_19846 4.04e-219 606.0 COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,1RMTM@1236|Gammaproteobacteria,1XUIJ@135623|Vibrionales 135623|Vibrionales F Belongs to the D-alanine--D-alanine ligase family ddl GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008716,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Dala_Dala_lig_C,Dala_Dala_lig_N k141_23809_4 674977.VMC_42250 4.16e-58 182.0 2AW5Q@1|root,31N0Q@2|Bacteria,1QJSF@1224|Proteobacteria,1THTS@1236|Gammaproteobacteria,1XXI7@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF3319) VPA0887 - - - - - - - - - - - DUF3319 k141_23809_5 1219076.N646_4285 7.38e-68 205.0 COG0023@1|root,COG0023@2|Bacteria,1MZ8T@1224|Proteobacteria,1S929@1236|Gammaproteobacteria,1XXTP@135623|Vibrionales 135623|Vibrionales J COG0023 Translation initiation factor 1 (eIF-1 SUI1) and related proteins yciH - - ko:K03113 ko03013,map03013 - - - ko00000,ko00001,ko03012 - - - SUI1 k141_23809_6 672.VV93_v1c43490 1.15e-13 72.0 COG1835@1|root,COG1835@2|Bacteria,1RHQR@1224|Proteobacteria,1S8IU@1236|Gammaproteobacteria,1XXEB@135623|Vibrionales 135623|Vibrionales I Acyltransferase family - - - - - - - - - - - - Acyl_transf_3 k141_5996_1 498211.CJA_3072 8.34e-21 91.3 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MV8W@1224|Proteobacteria,1RSN6@1236|Gammaproteobacteria,1FI6I@10|Cellvibrio 1236|Gammaproteobacteria P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec k141_5996_2 203122.Sde_1096 7.45e-101 307.0 COG0644@1|root,COG0644@2|Bacteria,1R41S@1224|Proteobacteria,1SME7@1236|Gammaproteobacteria,46D2G@72275|Alteromonadaceae 1236|Gammaproteobacteria C Tryptophan halogenase - - 1.14.19.9 ko:K14266 ko00404,ko01130,map00404,map01130 M00789,M00790 R09570 RC00949 ko00000,ko00001,ko00002,ko01000 - - - Trp_halogenase k141_3624_1 218284.CCDN010000001_gene524 2.47e-107 327.0 COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HB1B@91061|Bacilli,1ZC0T@1386|Bacillus 91061|Bacilli T Signal transduction histidine kinase phoR - 2.7.13.3 ko:K07636 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_9,sCache_like k141_10723_1 1121921.KB898716_gene11 5.34e-47 162.0 COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,1RN6I@1236|Gammaproteobacteria,2PMQ0@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria H Elongator protein 3, MiaB family, Radical SAM yggW GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - - - - - - - - - - HemN_C,Radical_SAM k141_9569_4 1453501.JELR01000001_gene1881 3.35e-118 351.0 COG0025@1|root,COG0025@2|Bacteria,1MW5T@1224|Proteobacteria,1RPH6@1236|Gammaproteobacteria,467E9@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0025 NhaP-type Na H and K H antiporters nhaP - - ko:K03316 - - - - ko00000 2.A.36 - - Na_H_Exchanger,cNMP_binding k141_34533_1 292414.TM1040_2517 8.89e-82 252.0 COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,2TR1J@28211|Alphaproteobacteria,4NB3D@97050|Ruegeria 28211|Alphaproteobacteria C hmm pf00107 ppsC - 1.6.5.5 ko:K00344 - - - - ko00000,ko01000 - - - ADH_N,ADH_zinc_N k141_16676_1 1042377.AFPJ01000008_gene1993 3.13e-271 745.0 COG1960@1|root,COG1960@2|Bacteria 2|Bacteria I acyl-CoA dehydrogenase activity fadE16 - 1.3.8.7 ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_2,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_16676_2 1042377.AFPJ01000008_gene1992 3.42e-141 402.0 2ARTX@1|root,31H5E@2|Bacteria,1NRN2@1224|Proteobacteria,1SKPJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_16676_3 1042377.AFPJ01000008_gene1991 2.6e-314 866.0 COG0388@1|root,COG0388@2|Bacteria,1MXG5@1224|Proteobacteria 1224|Proteobacteria T Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - - - - - - - - - - CN_hydrolase k141_16676_4 1042377.AFPJ01000008_gene1990 2.7e-261 723.0 COG0477@1|root,COG2814@2|Bacteria,1PR3J@1224|Proteobacteria,1RPWR@1236|Gammaproteobacteria 1236|Gammaproteobacteria EGP Major facilitator superfamily - - - - - - - - - - - - MFS_1,Sugar_tr k141_16676_6 1042377.AFPJ01000008_gene1989 2.55e-148 421.0 COG1073@1|root,COG1073@2|Bacteria 2|Bacteria S thiolester hydrolase activity - - 4.2.99.20 ko:K06889,ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R08166 RC02148,RC02475 ko00000,ko00001,ko00002,ko01000 - - - Abhydrolase_5 k141_16676_7 1042377.AFPJ01000008_gene1988 1.32e-143 409.0 COG4221@1|root,COG4221@2|Bacteria,1RF5D@1224|Proteobacteria,1S5AC@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short k141_16676_8 1042377.AFPJ01000008_gene1987 1.87e-130 371.0 2BY2Y@1|root,33PDR@2|Bacteria,1NTQC@1224|Proteobacteria,1SMBZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_16676_9 1042377.AFPJ01000008_gene1986 3.81e-238 667.0 COG0446@1|root,COG1773@1|root,COG0446@2|Bacteria,COG1773@2|Bacteria,1NR3M@1224|Proteobacteria,1RQ07@1236|Gammaproteobacteria,46561@72275|Alteromonadaceae 1236|Gammaproteobacteria C NAD(FAD)-dependent dehydrogenases rubB - 1.18.1.1 ko:K05297 ko00071,map00071 - R02000 - ko00000,ko00001,ko01000 - - - Pyr_redox_2,Rubredoxin k141_16676_10 1042377.AFPJ01000008_gene1985 1.19e-231 637.0 29UH5@1|root,30FU6@2|Bacteria,1NQUP@1224|Proteobacteria,1SKVR@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_16676_11 1042377.AFPJ01000008_gene1984 3.62e-103 300.0 COG1853@1|root,COG1853@2|Bacteria,1RGYM@1224|Proteobacteria,1S97V@1236|Gammaproteobacteria,468UV@72275|Alteromonadaceae 1236|Gammaproteobacteria S Flavin reductase like domain - - - - - - - - - - - - Flavin_Reduct k141_16676_12 1042377.AFPJ01000008_gene1983 8.83e-192 536.0 COG0119@1|root,COG0119@2|Bacteria,1MUMX@1224|Proteobacteria,1RS4M@1236|Gammaproteobacteria,4674Q@72275|Alteromonadaceae 1236|Gammaproteobacteria E HMGL-like - - 4.1.3.4 ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 M00036,M00088 R01360,R08090 RC00502,RC00503,RC01118,RC01946 ko00000,ko00001,ko00002,ko01000 - - - HMGL-like k141_16676_13 1042377.AFPJ01000008_gene1982 3.2e-242 671.0 COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,1RNB5@1236|Gammaproteobacteria,465ME@72275|Alteromonadaceae 1236|Gammaproteobacteria C CoA-transferase family III - - - - - - - - - - - - CoA_transf_3 k141_16676_14 1042377.AFPJ01000008_gene1981 7.57e-139 395.0 COG0664@1|root,COG0664@2|Bacteria,1MZJG@1224|Proteobacteria,1SZ1W@1236|Gammaproteobacteria,46BFX@72275|Alteromonadaceae 1236|Gammaproteobacteria K helix_turn_helix, cAMP Regulatory protein - - - ko:K01420 - - - - ko00000,ko03000 - - - HTH_Crp_2,cNMP_binding k141_16676_15 1042377.AFPJ01000008_gene1980 7.93e-255 702.0 COG0500@1|root,COG2226@2|Bacteria,1R41W@1224|Proteobacteria,1SGSF@1236|Gammaproteobacteria,469U4@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Putative methyltransferase - - - - - - - - - - - - Methyltransf_25 k141_16676_16 1042377.AFPJ01000008_gene1979 2.33e-66 204.0 2E4NX@1|root,32ZHQ@2|Bacteria,1N9UY@1224|Proteobacteria,1SIVP@1236|Gammaproteobacteria,46BYT@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_16676_17 1042377.AFPJ01000008_gene1978 3.39e-107 320.0 COG1024@1|root,COG1024@2|Bacteria,1PJ4R@1224|Proteobacteria,1S2FJ@1236|Gammaproteobacteria,46ASV@72275|Alteromonadaceae 1236|Gammaproteobacteria I Enoyl-CoA hydratase/isomerase - - 5.3.3.18 ko:K15866 ko00360,ko01120,map00360,map01120 - R09837,R09839 RC00004,RC00326,RC02689,RC03003 ko00000,ko00001,ko01000 - - - ECH_1 k141_16676_18 1042377.AFPJ01000008_gene1977 1.56e-193 552.0 COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,1RP7E@1236|Gammaproteobacteria,46CIJ@72275|Alteromonadaceae 1236|Gammaproteobacteria J Amidase - - 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Amidase k141_16676_19 1042377.AFPJ01000008_gene1976 3.44e-301 825.0 COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,1RQ3D@1236|Gammaproteobacteria,4688W@72275|Alteromonadaceae 1236|Gammaproteobacteria H AMP-binding enzyme C-terminal domain - - 6.2.1.30 ko:K01912 ko00360,ko01120,ko05111,map00360,map01120,map05111 - R02539 RC00004,RC00014 ko00000,ko00001,ko01000 - - - AMP-binding,AMP-binding_C_2 k141_16676_20 1042377.AFPJ01000008_gene1975 1.37e-236 662.0 COG2079@1|root,COG2079@2|Bacteria,1MX2N@1224|Proteobacteria,1RRYU@1236|Gammaproteobacteria,46ADX@72275|Alteromonadaceae 1236|Gammaproteobacteria S MmgE/PrpD family - - - - - - - - - - - - MmgE_PrpD k141_16676_21 1042377.AFPJ01000008_gene1974 8.26e-237 661.0 COG2079@1|root,COG2079@2|Bacteria,1R5UM@1224|Proteobacteria,1RS1P@1236|Gammaproteobacteria,46A6T@72275|Alteromonadaceae 1236|Gammaproteobacteria S MmgE/PrpD family - - - - - - - - - - - - MmgE_PrpD k141_16676_22 1042377.AFPJ01000008_gene1973 9.25e-121 348.0 COG0066@1|root,COG0066@2|Bacteria,1RC7N@1224|Proteobacteria,1S2UV@1236|Gammaproteobacteria,46ANE@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate leuD_2 - 4.2.1.33,4.2.1.35 ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R10170 RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase_C k141_16676_23 1042377.AFPJ01000008_gene1972 8.18e-277 765.0 COG0065@1|root,COG0065@2|Bacteria,1MVYR@1224|Proteobacteria,1S0G5@1236|Gammaproteobacteria,469RW@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate - - 4.2.1.33,4.2.1.35 ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170 RC00497,RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase k141_16676_24 1042377.AFPJ01000008_gene1971 3.73e-147 421.0 COG0346@1|root,COG0346@2|Bacteria,1RDMC@1224|Proteobacteria,1SHXD@1236|Gammaproteobacteria,46AYP@72275|Alteromonadaceae 1236|Gammaproteobacteria E lactoylglutathione lyase activity - - - - - - - - - - - - - k141_16676_25 1042377.AFPJ01000008_gene1970 6.39e-162 456.0 28PH0@1|root,2ZC7M@2|Bacteria,1R6YG@1224|Proteobacteria,1SK8N@1236|Gammaproteobacteria,469TU@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_16676_26 163908.KB235896_gene457 1.47e-17 88.2 COG0451@1|root,COG0451@2|Bacteria,1G0RF@1117|Cyanobacteria,1HIFQ@1161|Nostocales 1117|Cyanobacteria GM PFAM NAD dependent epimerase dehydratase family - - - - - - - - - - - - Epimerase,NAD_binding_10 k141_16676_27 221288.JH992901_gene2785 3.71e-57 190.0 2CHK1@1|root,2ZBVE@2|Bacteria,1GK2F@1117|Cyanobacteria,1JK97@1189|Stigonemataceae 1117|Cyanobacteria S Red chlorophyll catabolite reductase (RCC reductase) - - - - - - - - - - - - RCC_reductase k141_16676_28 1042377.AFPJ01000008_gene1969 4.21e-104 307.0 2BJ1M@1|root,2ZFAZ@2|Bacteria,1P4CP@1224|Proteobacteria,1SVP0@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_16676_29 1042377.AFPJ01000008_gene1968 7.01e-154 441.0 COG4188@1|root,COG4188@2|Bacteria,1NQWE@1224|Proteobacteria,1SMHQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Alpha/beta hydrolase family - - - - - - - - - - - - - k141_16676_30 1453501.JELR01000001_gene2072 5.8e-71 214.0 COG0789@1|root,COG0789@2|Bacteria,1RGYB@1224|Proteobacteria,1S6Y1@1236|Gammaproteobacteria,467A4@72275|Alteromonadaceae 1236|Gammaproteobacteria K helix_turn_helix, mercury resistance VL23_01195 - - - - - - - - - - - MerR_1 k141_16676_31 1279017.AQYJ01000026_gene177 6.91e-63 192.0 COG0776@1|root,COG0776@2|Bacteria,1RH5Z@1224|Proteobacteria,1S61Z@1236|Gammaproteobacteria,46792@72275|Alteromonadaceae 1236|Gammaproteobacteria K This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control himA GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - ko:K04764 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding k141_16676_32 1279017.AQYJ01000026_gene178 0.0 1313.0 COG0072@1|root,COG0072@2|Bacteria,1MWKS@1224|Proteobacteria,1RMIH@1236|Gammaproteobacteria,464S9@72275|Alteromonadaceae 1236|Gammaproteobacteria J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily pheT GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iG2583_1286.G2583_2160,iPC815.YPO2428 B3_4,B5,FDX-ACB,tRNA_bind k141_16676_33 1453501.JELR01000001_gene2069 7.41e-160 452.0 COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,1RN22@1236|Gammaproteobacteria,465BM@72275|Alteromonadaceae 1236|Gammaproteobacteria J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily pheS GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 ko:K01889 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iJN746.PP_2469 Phe_tRNA-synt_N,tRNA-synt_2d k141_11933_1 237727.NAP1_03145 2.13e-77 244.0 COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,1MUDN@1224|Proteobacteria,2U247@28211|Alphaproteobacteria,2KEA1@204457|Sphingomonadales 204457|Sphingomonadales P Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B,Rhodanese k141_25004_1 1379270.AUXF01000005_gene479 1.5e-71 231.0 COG2204@1|root,COG2204@2|Bacteria,1ZT50@142182|Gemmatimonadetes 142182|Gemmatimonadetes T Bacterial regulatory protein, Fis family - - - - - - - - - - - - HTH_8,Response_reg,Sigma54_activat k141_25004_2 1331060.RLDS_10005 1.47e-09 58.5 COG3191@1|root,COG3191@2|Bacteria,1MWDP@1224|Proteobacteria,2TUI2@28211|Alphaproteobacteria,2K8NN@204457|Sphingomonadales 204457|Sphingomonadales EQ Peptidase family S58 - - 3.4.11.19 ko:K01266 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S58 k141_15535_1 218284.CCDN010000010_gene4377 3.45e-108 313.0 COG0244@1|root,COG0244@2|Bacteria,1V3JJ@1239|Firmicutes,4HH0N@91061|Bacilli,1ZBGK@1386|Bacillus 91061|Bacilli J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors rplJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02864 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L10 k141_15535_2 218284.CCDN010000010_gene4376 5.01e-69 209.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,4HIGQ@91061|Bacilli,1ZG84@1386|Bacillus 91061|Bacilli J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation rplL - - ko:K02935 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L12,Ribosomal_L12_N k141_15535_3 218284.CCDN010000010_gene4375 1.81e-26 102.0 COG2813@1|root,COG2813@2|Bacteria,1V1BG@1239|Firmicutes,4HHCA@91061|Bacilli,1ZBPR@1386|Bacillus 91061|Bacilli J Methyltransferase rsmC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 2.1.1.172 ko:K00564 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - MTS k141_14327_1 223926.28807692 0.0 1334.0 COG0553@1|root,COG0553@2|Bacteria,1MX6H@1224|Proteobacteria,1RNRZ@1236|Gammaproteobacteria,1XTMU@135623|Vibrionales 135623|Vibrionales K Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair rapA GO:0000166,GO:0003674,GO:0003824,GO:0004386,GO:0005488,GO:0005524,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - ko:K03580 - - - - ko00000,ko01000,ko03021 - - - Helicase_C,RapA_C,SNF2_N k141_14327_2 223926.28807693 0.0 879.0 COG1875@1|root,COG1875@2|Bacteria,1MUX1@1224|Proteobacteria,1RMQN@1236|Gammaproteobacteria,1XTED@135623|Vibrionales 135623|Vibrionales T ATPase related to phosphate starvation-inducible protein PhoH - - - ko:K07175 - - - - ko00000 - - - PIN_4,PhoH k141_2754_2 223926.28809007 1.13e-52 166.0 2EA1K@1|root,3346W@2|Bacteria,1NBQF@1224|Proteobacteria,1SCG9@1236|Gammaproteobacteria,1XYID@135623|Vibrionales 135623|Vibrionales S Nitrogen fixation protein NifW - - - - - - - - - - - - NifW k141_20491_1 218284.CCDN010000002_gene2391 2.33e-96 293.0 COG0477@1|root,COG2814@2|Bacteria,1V0D1@1239|Firmicutes,4HESH@91061|Bacilli,1ZR88@1386|Bacillus 91061|Bacilli EGP Transmembrane secretion effector - - - - - - - - - - - - MFS_1 k141_32342_1 55529.EKX33572 0.00053 44.7 COG1597@1|root,KOG1116@2759|Eukaryota 2759|Eukaryota I D-erythro-sphingosine kinase activity - - 2.7.1.91 ko:K04718 ko00600,ko01100,ko04020,ko04071,ko04072,ko04370,ko04371,ko04666,ko05152,map00600,map01100,map04020,map04071,map04072,map04370,map04371,map04666,map05152 M00100 R01926,R02976 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - DAGK_cat k141_32342_2 1122214.AQWH01000008_gene1481 0.000703 45.4 COG0665@1|root,COG0665@2|Bacteria,1MVIZ@1224|Proteobacteria,2TSQI@28211|Alphaproteobacteria,2PJ0V@255475|Aurantimonadaceae 28211|Alphaproteobacteria C FAD dependent oxidoreductase - - 1.4.5.1 ko:K00285 ko00360,map00360 - R01374,R09493 RC00006,RC00025 ko00000,ko00001,ko01000 - - - DAO k141_25318_1 574375.BAGA_18835 1.11e-08 56.6 COG4722@1|root,COG4722@2|Bacteria,1VZIH@1239|Firmicutes,4I8NR@91061|Bacilli,1ZJI2@1386|Bacillus 91061|Bacilli S Phage tail protein - - - - - - - - - - - - Sipho_tail k141_25318_2 218284.CCDN010000001_gene920 4.04e-15 79.3 COG5412@1|root,COG5412@2|Bacteria,1TQ28@1239|Firmicutes,4HCMX@91061|Bacilli,1ZEVU@1386|Bacillus 91061|Bacilli D Phage tail tape measure protein, TP901 family - - - - - - - - - - - - PhageMin_Tail k141_37125_1 1196031.ALEG01000039_gene1910 3.93e-96 287.0 COG3023@1|root,COG3023@2|Bacteria,1V5SV@1239|Firmicutes,4HI8B@91061|Bacilli,1ZG3Z@1386|Bacillus 91061|Bacilli MV Ami_2 - - - - - - - - - - - - Amidase_2,Cu_amine_oxidN1,LysM,PG_binding_1 k141_11050_1 1453501.JELR01000005_gene1570 1.3e-56 199.0 COG0845@1|root,COG1994@1|root,COG0845@2|Bacteria,COG1994@2|Bacteria,1MW9I@1224|Proteobacteria,1RRTY@1236|Gammaproteobacteria,4685K@72275|Alteromonadaceae 1236|Gammaproteobacteria M Peptidase M50 - - - ko:K16922 - - - - ko00000,ko01002 - - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 k141_8692_1 935836.JAEL01000029_gene3575 7.24e-97 300.0 COG1368@1|root,COG1368@2|Bacteria,1TRMA@1239|Firmicutes,4HFA5@91061|Bacilli,1ZDG2@1386|Bacillus 91061|Bacilli M Sulfatase - - - - - - - - - - - - Sulfatase k141_29979_1 743836.AYNA01000111_gene18 4.46e-15 69.7 2C3CF@1|root,32RRR@2|Bacteria,1MZUG@1224|Proteobacteria,2UC1Q@28211|Alphaproteobacteria,370RI@31993|Methylocystaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF3175) - - - - - - - - - - - - DUF3175 k141_29979_2 236097.ADG881_484 6.36e-94 279.0 COG0625@1|root,COG0625@2|Bacteria,1NE6Z@1224|Proteobacteria,1RRET@1236|Gammaproteobacteria,1XNB2@135619|Oceanospirillales 135619|Oceanospirillales O Glutathione S-transferase, C-terminal domain - - - - - - - - - - - - GST_C_3,GST_N k141_14581_1 1173028.ANKO01000030_gene3283 8.9e-50 171.0 COG0438@1|root,COG0438@2|Bacteria,1G1X1@1117|Cyanobacteria,1HH59@1150|Oscillatoriales 1117|Cyanobacteria M Glycosyl transferase 4-like domain - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 k141_14581_2 1464048.JNZS01000003_gene1086 1.56e-20 92.8 COG2124@1|root,COG2124@2|Bacteria,2I8CJ@201174|Actinobacteria,4DIER@85008|Micromonosporales 201174|Actinobacteria Q Cytochrome P450 - - - - - - - - - - - - p450 k141_9870_1 1453501.JELR01000001_gene1957 5.76e-86 266.0 COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,1RQ0H@1236|Gammaproteobacteria,463ZB@72275|Alteromonadaceae 1236|Gammaproteobacteria E Threonine synthase thrC GO:0003674,GO:0003824,GO:0004795,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 - - iLF82_1304.LF82_2261,iNRG857_1313.NRG857_00025 PALP,Thr_synth_N k141_20492_1 1123053.AUDG01000045_gene2027 3.28e-11 62.8 COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,1RS05@1236|Gammaproteobacteria,1X0AT@135613|Chromatiales 135613|Chromatiales S Pirin C-terminal cupin domain - - - ko:K06911 - - - - ko00000 - - - Pirin,Pirin_C k141_20492_2 56780.SYN_01162 1.17e-19 87.0 COG0428@1|root,COG0428@2|Bacteria,1R40E@1224|Proteobacteria,43B49@68525|delta/epsilon subdivisions,2X6I2@28221|Deltaproteobacteria 28221|Deltaproteobacteria P ZIP Zinc transporter - - - ko:K16267 - - - - ko00000,ko02000 2.A.5.4.11 - - Zip k141_34805_2 796606.BMMGA3_14420 2.88e-18 76.6 2EVX5@1|root,33PAU@2|Bacteria,1W2JM@1239|Firmicutes,4HSMC@91061|Bacilli,1ZK3D@1386|Bacillus 91061|Bacilli S YuzL-like protein - - - - - - - - - - - - YuzL k141_35947_2 316275.VSAL_I3032 6.73e-111 320.0 COG2148@1|root,COG2148@2|Bacteria,1R4J5@1224|Proteobacteria,1RP9R@1236|Gammaproteobacteria,1XT9C@135623|Vibrionales 135623|Vibrionales M COG2148 Sugar transferases involved in lipopolysaccharide synthesis - - - - - - - - - - - - Bac_transf k141_35947_3 1205908.AKXW01000020_gene1101 1.34e-146 422.0 COG0451@1|root,COG0451@2|Bacteria,1MX2J@1224|Proteobacteria,1RPHW@1236|Gammaproteobacteria,1XVMH@135623|Vibrionales 135623|Vibrionales M Male sterility protein galE-1 - - - - - - - - - - - Epimerase k141_35947_4 1205908.AKXW01000020_gene1100 1.37e-186 528.0 COG0438@1|root,COG0438@2|Bacteria,1N0DG@1224|Proteobacteria,1S0D6@1236|Gammaproteobacteria,1XVZ5@135623|Vibrionales 135623|Vibrionales M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_trans_4_2,Glycos_transf_1 k141_33633_1 1042377.AFPJ01000024_gene743 3.73e-94 294.0 COG2199@1|root,COG3706@2|Bacteria,1MWHH@1224|Proteobacteria,1RRU7@1236|Gammaproteobacteria,465TD@72275|Alteromonadaceae 1236|Gammaproteobacteria T 7TMR-DISM extracellular 2 - - - - - - - - - - - - 7TMR-DISMED2,7TMR-DISM_7TM,GGDEF k141_33633_2 998088.B565_2025 5.83e-134 397.0 2C7MP@1|root,2Z7Q4@2|Bacteria,1NHK1@1224|Proteobacteria,1RQ17@1236|Gammaproteobacteria,1Y4YH@135624|Aeromonadales 135624|Aeromonadales S Methyltransferase domain - - - - - - - - - - - - Methyltransf_32 k141_19346_2 1042377.AFPJ01000012_gene1378 4.37e-24 93.2 COG3529@1|root,COG3529@2|Bacteria,1NPXJ@1224|Proteobacteria,1SHB8@1236|Gammaproteobacteria,4696D@72275|Alteromonadaceae 1236|Gammaproteobacteria S nucleic-acid-binding protein containing a Zn-ribbon domain - - - ko:K07070 - - - - ko00000 - - - DUF2387 k141_15807_1 1122194.AUHU01000003_gene2119 5.75e-248 714.0 COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,1RNIF@1236|Gammaproteobacteria,465NJ@72275|Alteromonadaceae 1236|Gammaproteobacteria P Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family cecA_2 - - ko:K07239 - - - - ko00000 2.A.6.1 - - ACR_tran k141_11051_1 218284.CCDN010000001_gene1331 5.01e-106 317.0 COG0508@1|root,COG0508@2|Bacteria,1TP3C@1239|Firmicutes,4HBVM@91061|Bacilli,1ZBCB@1386|Bacillus 91061|Bacilli C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) odhB - 2.3.1.61 ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R02570,R02571,R08549 RC00004,RC02727,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding k141_8693_1 1196031.ALEG01000008_gene5051 1.4e-115 345.0 COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,4H9SZ@91061|Bacilli,1ZAX7@1386|Bacillus 91061|Bacilli E Sodium alanine symporter glnT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03310,ko:K11626 ko02020,map02020 - - - ko00000,ko00001 2.A.25 - - Na_Ala_symp k141_3999_1 1424334.W822_11600 8.69e-43 155.0 COG0446@1|root,COG0446@2|Bacteria,1MXA9@1224|Proteobacteria,2VHVI@28216|Betaproteobacteria,3T2YC@506|Alcaligenaceae 28216|Betaproteobacteria C BFD-like [2Fe-2S] binding domain ooxA - - - - - - - - - - - Fer2_BFD,Pyr_redox_2 k141_3999_2 298386.PBPRB0770 7.78e-84 262.0 COG0583@1|root,COG0583@2|Bacteria,1MX2A@1224|Proteobacteria,1RPHN@1236|Gammaproteobacteria,1Y264@135623|Vibrionales 135623|Vibrionales K COG0583 Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_3999_3 754436.JCM19237_2251 2.72e-109 324.0 2C3WA@1|root,2Z8P1@2|Bacteria,1R8VC@1224|Proteobacteria,1S5UD@1236|Gammaproteobacteria,1XZXB@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_3999_4 1202962.KB907154_gene674 2.47e-247 695.0 COG4166@1|root,COG4166@2|Bacteria,1P91R@1224|Proteobacteria,1S0FB@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Bacterial extracellular solute-binding proteins, family 5 Middle - - - - - - - - - - - - SBP_bac_5 k141_28904_1 1042377.AFPJ01000008_gene1956 2.6e-190 560.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MV8W@1224|Proteobacteria,1RQEQ@1236|Gammaproteobacteria,463XU@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec k141_32343_1 1380347.JNII01000006_gene1769 4.44e-10 65.9 COG0454@1|root,COG0454@2|Bacteria,COG0456@2|Bacteria,2GN2X@201174|Actinobacteria,4EW17@85013|Frankiales 201174|Actinobacteria K Acetyltransferase (GNAT) family - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_7 k141_6414_1 1191523.MROS_0252 1.43e-27 114.0 COG0795@1|root,COG0795@2|Bacteria 2|Bacteria M lipopolysaccharide-transporting ATPase activity lptF GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - ko:K07091,ko:K11720 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko02000 1.B.42.1 - iECED1_1282.ECED1_5114,iUMNK88_1353.UMNK88_5207 YjgP_YjgQ k141_37127_3 935836.JAEL01000037_gene4270 2.54e-24 93.2 2EVKJ@1|root,33P0M@2|Bacteria,1VMAC@1239|Firmicutes,4HSPI@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - k141_34806_1 1034347.CAHJ01000061_gene1058 3.52e-92 274.0 2DBXC@1|root,2ZBP3@2|Bacteria,1V1I2@1239|Firmicutes,4HB52@91061|Bacilli,1ZFJV@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3231) - - - - - - - - - - - - DUF3231 k141_27600_2 1453501.JELR01000001_gene2964 2.49e-80 251.0 28J16@1|root,2Z8Y7@2|Bacteria,1R657@1224|Proteobacteria,1SFYP@1236|Gammaproteobacteria,46BM2@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_19347_1 218284.CCDN010000001_gene1574 5.99e-57 182.0 COG1514@1|root,COG1514@2|Bacteria,1VAR5@1239|Firmicutes,4HMP4@91061|Bacilli,1ZI6M@1386|Bacillus 91061|Bacilli J 2'-5' RNA ligase superfamily - - - - - - - - - - - - 2_5_RNA_ligase2 k141_4000_1 42565.FP66_06965 5.34e-83 262.0 COG0204@1|root,COG3176@1|root,COG0204@2|Bacteria,COG3176@2|Bacteria,1MWIM@1224|Proteobacteria,1RQD4@1236|Gammaproteobacteria,1XHPJ@135619|Oceanospirillales 135619|Oceanospirillales I phospholipid glycerol acyltransferase - - - - - - - - - - - - Acetyltransf_5,Acyltransferase k141_4000_2 42565.FP66_06960 9.33e-22 89.4 COG1739@1|root,COG1739@2|Bacteria,1NFJC@1224|Proteobacteria,1RPBF@1236|Gammaproteobacteria,1XKAZ@135619|Oceanospirillales 135619|Oceanospirillales S Uncharacterized protein family UPF0029 - - - - - - - - - - - - DUF1949,UPF0029 k141_11052_1 218284.CCDN010000001_gene1631 1.18e-38 138.0 COG1366@1|root,COG1366@2|Bacteria,1UNBX@1239|Firmicutes,4HEFW@91061|Bacilli,1ZAYN@1386|Bacillus 91061|Bacilli T Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor) - - - - - - - - - - - - STAS k141_11052_2 218284.CCDN010000002_gene2203 2.02e-62 196.0 COG3764@1|root,COG3764@2|Bacteria,1V79B@1239|Firmicutes,4HJ8C@91061|Bacilli,1ZHDM@1386|Bacillus 91061|Bacilli M Sortase family - - - - - - - - - - - - Sortase k141_26689_1 935837.JAEK01000002_gene1981 4.07e-84 263.0 COG3428@1|root,COG3428@2|Bacteria,1TPUR@1239|Firmicutes,4HB3A@91061|Bacilli,1ZQQ4@1386|Bacillus 91061|Bacilli S Bacterial PH domain - - - ko:K08981 - - - - ko00000 - - - bPH_2 k141_15808_1 335541.Swol_2304 2.25e-35 131.0 COG0202@1|root,COG0202@2|Bacteria,1TPR8@1239|Firmicutes,248DS@186801|Clostridia,42JIS@68298|Syntrophomonadaceae 186801|Clostridia K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoA - 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L k141_15808_2 331869.BAL199_03904 3.61e-10 60.5 COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,2TRQH@28211|Alphaproteobacteria,4BPEE@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit rpsD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - ko:K02986 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S4,S4 k141_34807_2 218284.CCDN010000001_gene1709 4.04e-16 77.4 COG2509@1|root,COG2509@2|Bacteria,1TP9I@1239|Firmicutes,4HB7F@91061|Bacilli,1ZCNU@1386|Bacillus 91061|Bacilli S FAD-dependent - - - ko:K07137 - - - - ko00000 - - - HI0933_like,NAD_binding_8 k141_35948_1 243275.TDE_0588 9.15e-64 213.0 COG2986@1|root,COG2986@2|Bacteria,2J72J@203691|Spirochaetes 203691|Spirochaetes E Histidine ammonia-lyase hutH - 4.3.1.3 ko:K01745 ko00340,ko01100,map00340,map01100 M00045 R01168 RC00361 ko00000,ko00001,ko00002,ko01000 - - - Lyase_aromatic k141_28905_1 935836.JAEL01000078_gene151 2.33e-117 342.0 COG1230@1|root,COG1230@2|Bacteria,1TR92@1239|Firmicutes,4HBCQ@91061|Bacilli,1ZB56@1386|Bacillus 91061|Bacilli P COG1230 Co Zn Cd efflux system component czcD - - ko:K16264 - - - - ko00000,ko02000 2.A.4.1 - - Cation_efflux k141_14582_1 1210884.HG799471_gene14689 1.13e-31 125.0 COG0841@1|root,COG0841@2|Bacteria,2IWU0@203682|Planctomycetes 203682|Planctomycetes V Protein export membrane protein - - - ko:K18299 - M00641 - - ko00000,ko00002,ko01504,ko02000 2.A.6.2.16 - - ACR_tran k141_14582_2 1122164.JHWF01000003_gene2166 5.58e-14 76.6 COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,1RMI7@1236|Gammaproteobacteria,1JE92@118969|Legionellales 118969|Legionellales M Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - ko:K03585 ko01501,ko01503,map01501,map01503 M00646,M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,8.A.1.6 - - Biotin_lipoyl_2,HlyD_D23 k141_31262_1 218284.CCDN010000008_gene4171 3.84e-107 310.0 COG0663@1|root,COG0663@2|Bacteria,1V6CZ@1239|Firmicutes,4HFPC@91061|Bacilli,1ZBFS@1386|Bacillus 91061|Bacilli S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily ytoA - - - - - - - - - - - Hexapep k141_31262_2 218284.CCDN010000008_gene4172 2.74e-177 496.0 COG2267@1|root,COG2267@2|Bacteria,1UZ5S@1239|Firmicutes,4HEHP@91061|Bacilli,1ZBD1@1386|Bacillus 91061|Bacilli I Alpha beta hydrolase ytpA GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0008150,GO:0008152,GO:0016020,GO:0016298,GO:0016787,GO:0016788,GO:0044238,GO:0071704 3.1.1.5 ko:K01048 ko00564,map00564 - - - ko00000,ko00001,ko01000 - - - Hydrolase_4 k141_4001_1 1294265.JCM21738_1820 3.04e-120 357.0 COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HACS@91061|Bacilli,1ZATG@1386|Bacillus 91061|Bacilli IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - 6.2.1.3 ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding,AMP-binding_C k141_6415_1 1123269.NX02_25780 5e-39 141.0 COG3324@1|root,COG3324@2|Bacteria,1R81W@1224|Proteobacteria,2U6BE@28211|Alphaproteobacteria,2K4NC@204457|Sphingomonadales 204457|Sphingomonadales S enzyme related to lactoylglutathione lyase - - - ko:K06996 - - - - ko00000 - - - Glyoxalase k141_22992_1 1279017.AQYJ01000028_gene2079 5.73e-180 526.0 COG2755@1|root,COG2755@2|Bacteria,1MXTS@1224|Proteobacteria,1RTPH@1236|Gammaproteobacteria,46419@72275|Alteromonadaceae 1236|Gammaproteobacteria E Concanavalin A-like lectin/glucanases superfamily - - - - - - - - - - - - Laminin_G_3 k141_22992_3 1453501.JELR01000002_gene1336 1.28e-163 487.0 COG0823@1|root,COG0823@2|Bacteria,1R3VN@1224|Proteobacteria,1RNKG@1236|Gammaproteobacteria,46408@72275|Alteromonadaceae 1236|Gammaproteobacteria U COG0823 Periplasmic component of the Tol biopolymer transport system - - - - - - - - - - - - PD40 k141_33636_1 525368.HMPREF0591_3092 7.86e-73 236.0 COG2114@1|root,COG2267@1|root,COG2114@2|Bacteria,COG2267@2|Bacteria,2IASU@201174|Actinobacteria,232Z7@1762|Mycobacteriaceae 201174|Actinobacteria IT PFAM Adenylate and Guanylate cyclase catalytic domain lipJ - - - - - - - - - - - Abhydrolase_1,Guanylate_cyc k141_18234_1 13690.CP98_00271 8.67e-50 169.0 COG1120@1|root,COG1120@2|Bacteria,1QPWJ@1224|Proteobacteria,2U1TK@28211|Alphaproteobacteria,2K1EJ@204457|Sphingomonadales 204457|Sphingomonadales HP ABC transporter - - 3.6.3.34 ko:K02013 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 - - ABC_tran k141_4002_1 1227352.C173_29481 6.31e-24 105.0 COG0508@1|root,COG0508@2|Bacteria,1TQSH@1239|Firmicutes,4HBSU@91061|Bacilli,26SPG@186822|Paenibacillaceae 91061|Bacilli C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex bkdB - 2.3.1.12,2.3.1.168 ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 M00036,M00307 R00209,R02569,R02662,R03174,R04097,R10998 RC00004,RC02727,RC02742,RC02857,RC02870 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding k141_15809_1 218284.CCDN010000004_gene3125 1.05e-96 301.0 COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,4HADT@91061|Bacilli,1ZCKV@1386|Bacillus 91061|Bacilli KT Sigma-54 interaction domain - - - - - - - - - - - - HTH_12,HTH_8,PAS,PAS_9,Sigma54_activat k141_26725_1 42565.FP66_11405 4.65e-71 218.0 COG3683@1|root,COG3683@2|Bacteria,1R4QA@1224|Proteobacteria,1RQ73@1236|Gammaproteobacteria,1XPU4@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF1007) - - - - - - - - - - - - DUF1007 k141_25353_1 1453501.JELR01000002_gene845 9.06e-132 386.0 COG0246@1|root,COG0246@2|Bacteria,1MVZ7@1224|Proteobacteria,1RNIZ@1236|Gammaproteobacteria,4641C@72275|Alteromonadaceae 1236|Gammaproteobacteria G COG0246 Mannitol-1-phosphate altronate dehydrogenases uxuB GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0006063,GO:0006064,GO:0006082,GO:0008150,GO:0008152,GO:0008866,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019585,GO:0019752,GO:0032787,GO:0042839,GO:0042840,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046365,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 1.1.1.57,1.1.1.67 ko:K00040,ko:K00045 ko00040,ko00051,ko01100,map00040,map00051,map01100 M00061 R00868,R02454 RC00085 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_2108,iECOK1_1307.ECOK1_4822,iUMN146_1321.UM146_22300,iUTI89_1310.UTI89_C5019 Mannitol_dh,Mannitol_dh_C k141_19386_1 1294265.JCM21738_397 8.59e-110 326.0 COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1TQ1N@1239|Firmicutes,4HATN@91061|Bacilli,1ZC5R@1386|Bacillus 91061|Bacilli S Belongs to the CinA family cinA - 3.5.1.42 ko:K03742,ko:K03743 ko00760,map00760 - R02322 RC00100 ko00000,ko00001,ko01000 - - - CinA,MoCF_biosynth k141_33688_1 1196031.ALEG01000044_gene4442 9.71e-101 302.0 COG0701@1|root,COG0701@2|Bacteria,1TQHK@1239|Firmicutes,4HB25@91061|Bacilli,1ZC03@1386|Bacillus 91061|Bacilli S permeases - - - ko:K07089 - - - - ko00000 - - - ArsP_1 k141_7467_1 665952.HMPREF1015_01741 5.04e-24 99.8 COG0161@1|root,COG0161@2|Bacteria,1TP9N@1239|Firmicutes,4H9QK@91061|Bacilli,1ZR67@1386|Bacillus 91061|Bacilli H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor bioA - 2.6.1.105,2.6.1.62 ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R03231,R10699 RC00006,RC00062,RC00887 ko00000,ko00001,ko00002,ko01000,ko01007 - - iSB619.SA_RS12705 Aminotran_3 k141_7467_2 521098.Aaci_2855 2.27e-18 85.1 COG0132@1|root,COG0132@2|Bacteria,1V4DE@1239|Firmicutes,4HID2@91061|Bacilli,278E2@186823|Alicyclobacillaceae 91061|Bacilli H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring bioD - 6.3.3.3 ko:K01935 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R03182 RC00868 ko00000,ko00001,ko00002,ko01000 - - - AAA_26 k141_23033_1 221109.22777402 3.8e-33 130.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HCMP@91061|Bacilli 91061|Bacilli L Integrase - - - ko:K07482 - - - - ko00000 - - - HTH_38,rve k141_5120_1 1042377.AFPJ01000019_gene2520 4.46e-40 140.0 COG3735@1|root,COG3735@2|Bacteria,1MVCW@1224|Proteobacteria,1RRI8@1236|Gammaproteobacteria,4659X@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria ybaP - - ko:K09973 - - - - ko00000 - - - TraB k141_5120_2 1453501.JELR01000001_gene2037 1.09e-42 150.0 COG3746@1|root,COG3746@2|Bacteria,1RG6T@1224|Proteobacteria,1S412@1236|Gammaproteobacteria,468U6@72275|Alteromonadaceae 1236|Gammaproteobacteria P Phosphate-selective porin O and P oprO - - ko:K07221 - - - - ko00000,ko02000 1.B.5.1 - - Porin_O_P k141_26726_1 1294265.JCM21738_936 1.36e-121 352.0 2BZRV@1|root,2Z8AV@2|Bacteria,1UX40@1239|Firmicutes,4HAVP@91061|Bacilli,1ZDM4@1386|Bacillus 91061|Bacilli S Nuclease-related domain - - - - - - - - - - - - NERD k141_18258_1 1347369.CCAD010000042_gene893 5.12e-127 365.0 COG0785@1|root,COG0785@2|Bacteria,1TQH1@1239|Firmicutes,4H9UJ@91061|Bacilli,1ZBPX@1386|Bacillus 91061|Bacilli O cytochrome c biogenesis protein ccdA - - ko:K06196 - - - - ko00000,ko02000 5.A.1.2 - - DsbD k141_34825_1 1385513.N780_05950 5.11e-56 190.0 COG2132@1|root,COG2132@2|Bacteria,1TQJK@1239|Firmicutes,4IRUW@91061|Bacilli,2YBG3@289201|Pontibacillus 91061|Bacilli Q Multicopper oxidase - - - - - - - - - - - - Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3,Cupredoxin_1 k141_24120_1 218284.CCDN010000010_gene4337 1.54e-168 474.0 COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,4H9R8@91061|Bacilli,1ZBD2@1386|Bacillus 91061|Bacilli P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates ecfA1 - - ko:K16786 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran k141_24120_2 218284.CCDN010000010_gene4336 3.72e-170 479.0 COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,4HA7T@91061|Bacilli,1ZBBK@1386|Bacillus 91061|Bacilli P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates ecfA2 GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0008150,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085 - ko:K16787 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran k141_19388_1 414684.RC1_1984 2.77e-86 266.0 COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,2TRDM@28211|Alphaproteobacteria,2JP8N@204441|Rhodospirillales 204441|Rhodospirillales D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP - - - ko:K03593 - - - - ko00000,ko03029,ko03036 - - - FeS_assembly_P,ParA k141_2757_1 406124.ACPC01000005_gene3523 7.09e-114 340.0 COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,4H9VK@91061|Bacilli,1ZB07@1386|Bacillus 91061|Bacilli G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system - - 3.6.3.17 ko:K10548 ko02010,map02010 M00216 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.2.5 - - ABC_tran k141_13559_1 1453501.JELR01000002_gene870 4.8e-55 190.0 COG1629@1|root,COG4771@2|Bacteria,1MVFB@1224|Proteobacteria,1RNMS@1236|Gammaproteobacteria,466BD@72275|Alteromonadaceae 1236|Gammaproteobacteria P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec k141_25355_1 1294265.JCM21738_1814 7.98e-94 278.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,1ZBIW@1386|Bacillus 91061|Bacilli V COG1132 ABC-type multidrug transport system, ATPase and permease components yfiC3 - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran k141_8743_2 1453501.JELR01000002_gene957 2.14e-208 581.0 COG0189@1|root,COG0189@2|Bacteria,1MVUA@1224|Proteobacteria,1RMU0@1236|Gammaproteobacteria,4651A@72275|Alteromonadaceae 1236|Gammaproteobacteria H Belongs to the prokaryotic GSH synthase family gshB GO:0000287,GO:0003674,GO:0003824,GO:0004363,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0019184,GO:0034641,GO:0042398,GO:0043043,GO:0043167,GO:0043169,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:1901564,GO:1901566,GO:1901576 6.3.2.3 ko:K01920 ko00270,ko00480,ko01100,map00270,map00480,map01100 M00118 R00497,R10994 RC00096,RC00141 ko00000,ko00001,ko00002,ko01000 - - iECED1_1282.ECED1_3410,iECP_1309.ECP_2941 GSH-S_ATP,GSH-S_N k141_9917_1 1279017.AQYJ01000028_gene2160 5.4e-29 104.0 2C0ET@1|root,33A9M@2|Bacteria,1NGE5@1224|Proteobacteria,1SGID@1236|Gammaproteobacteria,4697N@72275|Alteromonadaceae 1236|Gammaproteobacteria S TIGRFAM TIGR02449 family protein VL23_04670 - - ko:K09892 - - - - ko00000,ko03036 - - - - k141_16030_1 1196028.ALEF01000060_gene1202 4.37e-103 310.0 COG2141@1|root,COG2141@2|Bacteria,1TQZ0@1239|Firmicutes,4HAF9@91061|Bacilli,4C55W@84406|Virgibacillus 91061|Bacilli C Luciferase-like monooxygenase - - 1.14.14.28 ko:K20938 - - - - ko00000,ko01000 - - - Bac_luciferase k141_10245_1 1453501.JELR01000002_gene614 5.46e-180 523.0 COG3008@1|root,COG3008@2|Bacteria,1MU1T@1224|Proteobacteria,1RN89@1236|Gammaproteobacteria,46474@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Paraquat-inducible protein B yebT GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006869,GO:0008150,GO:0009987,GO:0010876,GO:0016020,GO:0016021,GO:0016043,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0033036,GO:0042597,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071840,GO:0071944,GO:0120009 - ko:K06192 - - - - ko00000 - - - MlaD k141_5450_1 42565.FP66_04145 4.44e-148 422.0 COG0614@1|root,COG0614@2|Bacteria,1MVBY@1224|Proteobacteria,1RZ2W@1236|Gammaproteobacteria,1XS65@135619|Oceanospirillales 135619|Oceanospirillales P Periplasmic binding protein - - - - - - - - - - - - Peripla_BP_2 k141_13856_1 980584.AFPB01000163_gene2287 2.85e-29 123.0 COG0845@1|root,COG0845@2|Bacteria,4NG8S@976|Bacteroidetes,1HYRA@117743|Flavobacteriia,406U0@61432|unclassified Flavobacteriaceae 976|Bacteroidetes M Protein of unknown function (DUF3347) cusB - - ko:K07798 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.6.1.4,8.A.1 - - DUF3347,HlyD_D23,HlyD_D4 k141_35117_1 1307436.PBF_00360 1.86e-74 234.0 2AWED@1|root,31NAF@2|Bacteria,1V7YQ@1239|Firmicutes,4HJ74@91061|Bacilli,1ZDUZ@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - DUF4871 k141_35117_2 1196031.ALEG01000003_gene3341 1.64e-10 59.7 COG1595@1|root,COG1595@2|Bacteria,1V9ZH@1239|Firmicutes,4I56G@91061|Bacilli,1ZGIK@1386|Bacillus 91061|Bacilli K Sigma-70, region 4 - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_26987_1 981383.AEWH01000052_gene734 2.89e-21 92.0 COG0534@1|root,COG0534@2|Bacteria,1TQMT@1239|Firmicutes,4H9Y2@91061|Bacilli 91061|Bacilli V Mate efflux family protein yisQ - - - - - - - - - - - MatE k141_26987_2 1294265.JCM21738_2692 7.6e-12 64.3 COG0366@1|root,COG0366@2|Bacteria,1TNZ0@1239|Firmicutes,4HB67@91061|Bacilli,1ZAZP@1386|Bacillus 91061|Bacilli G Alpha amylase, N-terminal ig-like domain nplT - 3.2.1.133,3.2.1.135,3.2.1.54 ko:K01208 ko00500,ko01100,map00500,map01100 - R02112,R03122,R11262 - ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,Alpha-amylase_N,Malt_amylase_C k141_25677_1 1094508.Tsac_0122 1.24e-81 266.0 COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,2484Y@186801|Clostridia,42ER6@68295|Thermoanaerobacterales 186801|Clostridia J Belongs to the class-I aminoacyl-tRNA synthetase family leuS - 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Anticodon_1,tRNA-synt_1,tRNA-synt_1_2 k141_11410_1 1219076.N646_0316 6.61e-46 157.0 28RRT@1|root,2ZE4B@2|Bacteria,1RCHD@1224|Proteobacteria,1S345@1236|Gammaproteobacteria,1XTM3@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF3187) - - - - - - - - - - - - DUF3187 k141_11410_2 674977.VMC_18500 8.73e-155 437.0 COG4326@1|root,COG4326@2|Bacteria,1NRE6@1224|Proteobacteria,1S5IP@1236|Gammaproteobacteria,1XTRM@135623|Vibrionales 135623|Vibrionales S COG4326 Sporulation control protein - - - ko:K06377 - - - - ko00000 - - - Spo0M k141_11410_3 223926.28806265 1.27e-157 443.0 COG2188@1|root,COG2188@2|Bacteria,1MVFM@1224|Proteobacteria,1RNPE@1236|Gammaproteobacteria,1XSSC@135623|Vibrionales 135623|Vibrionales K histidine utilization repressor hutC - - ko:K05836 - - - - ko00000,ko03000 - - - GntR,UTRA k141_11410_4 1116375.VEJY3_06160 8.29e-276 757.0 COG1228@1|root,COG1228@2|Bacteria,1MUYR@1224|Proteobacteria,1RMI9@1236|Gammaproteobacteria,1XSFM@135623|Vibrionales 135623|Vibrionales F COG1228 Imidazolonepropionase and related amidohydrolases hutI GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0052803,GO:0052805,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.2.7 ko:K01468 ko00340,ko01100,map00340,map01100 M00045 R02288 RC00683 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1,Amidohydro_3 k141_7649_1 713586.KB900537_gene3376 8.85e-17 87.8 COG1879@1|root,COG1879@2|Bacteria,1MYP5@1224|Proteobacteria,1S84T@1236|Gammaproteobacteria 1236|Gammaproteobacteria G ABC-type sugar transport system periplasmic component - - - - - - - - - - - - Flg_new k141_12662_1 1279017.AQYJ01000022_gene2721 5.2e-51 180.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria,465ZZ@72275|Alteromonadaceae 1236|Gammaproteobacteria P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec k141_12662_2 1279017.AQYJ01000022_gene2720 3.94e-24 100.0 COG1629@1|root,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria,4652I@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec k141_24362_2 1121405.dsmv_3141 6.31e-15 71.2 COG0764@1|root,COG0764@2|Bacteria,1RH2T@1224|Proteobacteria,42SCN@68525|delta/epsilon subdivisions,2WP3E@28221|Deltaproteobacteria,2MK6G@213118|Desulfobacterales 28221|Deltaproteobacteria I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs fabZ - 4.2.1.59 ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121 RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FabA k141_29092_2 218284.CCDN010000006_gene3509 1.73e-36 128.0 COG1393@1|root,COG1393@2|Bacteria,1VA5Q@1239|Firmicutes,4HKQQ@91061|Bacilli,1ZH0I@1386|Bacillus 91061|Bacilli P Belongs to the ArsC family yusI - 1.20.4.1 ko:K00537 - - - - ko00000,ko01000 - - - ArsC,Glutaredoxin k141_36160_1 218284.CCDN010000007_gene3785 7.61e-49 167.0 COG2206@1|root,COG2206@2|Bacteria,1TR95@1239|Firmicutes,4HB8S@91061|Bacilli,1ZCD6@1386|Bacillus 91061|Bacilli T HD domain M1-161 - - - - - - - - - - - HD,HD_5 k141_7673_2 218284.CCDN010000001_gene1023 2.28e-78 240.0 COG3570@1|root,COG3570@2|Bacteria,1V5G9@1239|Firmicutes,4HH9E@91061|Bacilli,1ZFTN@1386|Bacillus 91061|Bacilli V Aminoglycoside/hydroxyurea antibiotic resistance kinase - - 2.7.1.72 ko:K04343 - M00766 R02225 RC00002,RC00078 br01600,ko00000,ko00002,ko01000,ko01504 - - - APH_6_hur k141_11454_1 1294265.JCM21738_929 7.91e-98 287.0 COG0454@1|root,COG0456@2|Bacteria,1V2FB@1239|Firmicutes,4HFUN@91061|Bacilli,1ZFIM@1386|Bacillus 91061|Bacilli K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases yhfO - - - - - - - - - - - Acetyltransf_1,Acetyltransf_4 k141_30182_1 1453501.JELR01000002_gene845 3.66e-164 470.0 COG0246@1|root,COG0246@2|Bacteria,1MVZ7@1224|Proteobacteria,1RNIZ@1236|Gammaproteobacteria,4641C@72275|Alteromonadaceae 1236|Gammaproteobacteria G COG0246 Mannitol-1-phosphate altronate dehydrogenases uxuB GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0006063,GO:0006064,GO:0006082,GO:0008150,GO:0008152,GO:0008866,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019585,GO:0019752,GO:0032787,GO:0042839,GO:0042840,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046365,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 1.1.1.57,1.1.1.67 ko:K00040,ko:K00045 ko00040,ko00051,ko01100,map00040,map00051,map01100 M00061 R00868,R02454 RC00085 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_2108,iECOK1_1307.ECOK1_4822,iUMN146_1321.UM146_22300,iUTI89_1310.UTI89_C5019 Mannitol_dh,Mannitol_dh_C k141_10272_1 218284.CCDN010000001_gene951 1.5e-107 318.0 COG0006@1|root,COG0006@2|Bacteria,1TQ44@1239|Firmicutes,4HAT7@91061|Bacilli,1ZB4P@1386|Bacillus 91061|Bacilli E COG0006 Xaa-Pro aminopeptidase yqhT - 3.4.11.9,3.4.13.9 ko:K01262,ko:K01271 - - - - ko00000,ko01000,ko01002 - - - Creatinase_N,Peptidase_M24 k141_23305_1 218284.CCDN010000005_gene3320 3.92e-140 398.0 COG2382@1|root,COG2382@2|Bacteria,1UCAC@1239|Firmicutes,4HC02@91061|Bacilli,1ZBAQ@1386|Bacillus 91061|Bacilli P COG2382 Enterochelin esterase and related enzymes yjcH - - ko:K07214 - - - - ko00000 - - - Esterase k141_32570_1 1294265.JCM21738_577 8.37e-83 254.0 COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,4HBX7@91061|Bacilli,1ZBN6@1386|Bacillus 91061|Bacilli KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance relA GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5 ko:K00951 ko00230,map00230 - R00429 RC00002,RC00078 ko00000,ko00001,ko01000 - - iYO844.BSU27600 ACT_4,HD_4,RelA_SpoT,TGS k141_17220_1 218284.CCDN010000002_gene2875 2e-56 188.0 COG1053@1|root,COG1053@2|Bacteria,1TPAR@1239|Firmicutes,4HAXN@91061|Bacilli,1ZBU7@1386|Bacillus 91061|Bacilli C COG1053 Succinate dehydrogenase fumarate reductase, flavoprotein subunit - - - ko:K13796 - - - - ko00000 - - - FAD_binding_2 k141_17220_2 218284.CCDN010000002_gene2874 4.64e-48 166.0 COG3333@1|root,COG3333@2|Bacteria,1TPE7@1239|Firmicutes,4HADN@91061|Bacilli,1ZBVK@1386|Bacillus 91061|Bacilli S Tripartite tricarboxylate transporter TctA family tctA - - ko:K07793 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.80.1 - - TctA k141_5487_1 218284.CCDN010000001_gene1528 1.39e-52 175.0 COG0006@1|root,COG0006@2|Bacteria,1TQ6R@1239|Firmicutes,4HA5I@91061|Bacilli,1ZBZE@1386|Bacillus 91061|Bacilli E COG0006 Xaa-Pro aminopeptidase ykvY - 3.4.13.9 ko:K01271 - - - - ko00000,ko01000,ko01002 - - - Creatinase_N,Peptidase_M24 k141_5487_2 1280390.CBQR020000101_gene2354 2.64e-35 125.0 COG0454@1|root,COG0454@2|Bacteria,1UID4@1239|Firmicutes,4IV3T@91061|Bacilli 91061|Bacilli K FR47-like protein - - - - - - - - - - - - Acetyltransf_10 k141_20747_1 223926.28810151 6.32e-251 702.0 COG1315@1|root,COG1315@2|Bacteria,1R40D@1224|Proteobacteria,1RZ2U@1236|Gammaproteobacteria,1XT9Y@135623|Vibrionales 135623|Vibrionales L polymerase, most proteins contain PALM domain, HD hydrolase domain and Zn-ribbon domain - - - ko:K09749 - - - - ko00000 - - - FapA k141_20747_2 1116375.VEJY3_24371 0.0 934.0 COG1444@1|root,COG1444@2|Bacteria,1NBA4@1224|Proteobacteria,1RPAM@1236|Gammaproteobacteria,1XT9I@135623|Vibrionales 135623|Vibrionales J Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) tmcA GO:0000049,GO:0000154,GO:0002097,GO:0002101,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008080,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0022613,GO:0030490,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0051391,GO:0051392,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1904812,GO:1990882,GO:1990883,GO:1990884 2.3.1.193 ko:K06957 - - - - ko00000,ko01000,ko03016 - - - DUF1726,GNAT_acetyltr_2,Helicase_RecD k141_20747_3 1116375.VEJY3_24376 1.19e-211 587.0 COG1475@1|root,COG1475@2|Bacteria,1NGXR@1224|Proteobacteria,1RNZ3@1236|Gammaproteobacteria,1XSQH@135623|Vibrionales 135623|Vibrionales K Belongs to the ParB family VVA1695 - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc k141_20747_4 1219076.N646_3464 3.84e-291 797.0 COG1192@1|root,COG1192@2|Bacteria,1NAJP@1224|Proteobacteria,1S2DK@1236|Gammaproteobacteria,1XSUA@135623|Vibrionales 135623|Vibrionales D COG1192 ATPases involved in chromosome partitioning parA - - - - - - - - - - - AAA_31 k141_20747_5 1219076.N646_3465 0.0 1259.0 COG1284@1|root,COG1284@2|Bacteria,1RDIV@1224|Proteobacteria,1S7JN@1236|Gammaproteobacteria,1XSIE@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF3346) rctB - - - - - - - - - - - DUF3346 k141_20747_6 223926.28808140 1.66e-89 264.0 2C4PJ@1|root,2ZS42@2|Bacteria,1P5XZ@1224|Proteobacteria,1SVFU@1236|Gammaproteobacteria,1XY1R@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_20747_7 223926.28808143 3.98e-28 102.0 2AWN9@1|root,31NJ0@2|Bacteria,1QK9N@1224|Proteobacteria,1TID5@1236|Gammaproteobacteria,1XYWS@135623|Vibrionales 135623|Vibrionales - - VVA0005 - - - - - - - - - - - - k141_20747_9 1116375.VEJY3_15801 1.1e-40 134.0 2C4PK@1|root,3333R@2|Bacteria,1N7VC@1224|Proteobacteria,1SCZA@1236|Gammaproteobacteria,1XYWF@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF3283) VVA0009 - - - - - - - - - - - DUF3283 k141_20747_10 945550.VISI1226_12016 7.17e-170 474.0 COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,1RP5N@1236|Gammaproteobacteria,1XTXW@135623|Vibrionales 135623|Vibrionales K transcriptional regulatory protein yeeN GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - - - - - - - - - - Transcrip_reg k141_20747_11 223926.28808161 2.36e-109 315.0 COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,1S3HH@1236|Gammaproteobacteria,1XUKI@135623|Vibrionales 135623|Vibrionales G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides - - 5.2.1.8 ko:K03768 - - - - ko00000,ko01000,ko03110 - - - Pro_isomerase k141_20747_12 1116375.VEJY3_15851 3.67e-73 221.0 COG3011@1|root,COG3011@2|Bacteria,1N08P@1224|Proteobacteria,1S8S3@1236|Gammaproteobacteria,1XXZP@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria - - - - - - - - - - - - DUF393 k141_30183_1 218284.CCDN010000002_gene2384 8.14e-17 75.1 2CJYE@1|root,32SB3@2|Bacteria,1VAGT@1239|Firmicutes,4HKFV@91061|Bacilli,1ZQTG@1386|Bacillus 91061|Bacilli S Family of unknown function (DUF5412) - - - - - - - - - - - - DUF5412 k141_7674_1 1453501.JELR01000001_gene2152 2.66e-79 243.0 COG0742@1|root,COG0742@2|Bacteria,1MX8Z@1224|Proteobacteria,1RMIB@1236|Gammaproteobacteria,466ZU@72275|Alteromonadaceae 1236|Gammaproteobacteria J Specifically methylates the guanosine in position 1516 of 16S rRNA rsmJ GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036308,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.242 ko:K15984 - - - - ko00000,ko01000,ko03009 - - - SAM_MT k141_7674_2 1453501.JELR01000001_gene2151 9.19e-16 71.6 2DQ16@1|root,334AZ@2|Bacteria,1N8CC@1224|Proteobacteria,1SCV9@1236|Gammaproteobacteria,46C0B@72275|Alteromonadaceae 1236|Gammaproteobacteria S SpoIIAA-like - - - - - - - - - - - - SpoIIAA-like k141_19693_1 467661.RKLH11_3911 1.74e-47 168.0 COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,2TRXG@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Transposase - - - ko:K07487 - - - - ko00000 - - - DDE_Tnp_1,DDE_Tnp_1_6,DUF772 k141_22005_1 935836.JAEL01000062_gene2111 3.91e-82 254.0 COG3589@1|root,COG3589@2|Bacteria,1TRIY@1239|Firmicutes,4HAHJ@91061|Bacilli,1ZDH2@1386|Bacillus 91061|Bacilli S Bacterial protein of unknown function (DUF871) yleB - 4.2.1.126 ko:K07106,ko:K09963 ko00520,ko01100,map00520,map01100 - R08555 RC00397,RC00746 ko00000,ko00001,ko01000 - - - DUF871 k141_23306_1 218284.CCDN010000002_gene2101 2.17e-71 223.0 COG2984@1|root,COG2984@2|Bacteria,1TPB0@1239|Firmicutes,4HESK@91061|Bacilli,1ZBBC@1386|Bacillus 91061|Bacilli S transport system, periplasmic component - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind k141_18564_1 218284.CCDN010000001_gene661 1.15e-97 305.0 COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,1TQVT@1239|Firmicutes,4HB6K@91061|Bacilli,1ZBS9@1386|Bacillus 91061|Bacilli U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secD GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD_SecF,Sec_GG k141_32571_1 221109.22778079 3.55e-57 192.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HB0J@91061|Bacilli,23J0G@182709|Oceanobacillus 91061|Bacilli I Acyl-CoA dehydrogenase, N-terminal domain fadE - 1.3.8.1 ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 - R01175,R01178,R02661,R03172,R04751 RC00052,RC00068,RC00076,RC00120,RC00148 ko00000,ko00001,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_12688_1 218284.CCDN010000001_gene1917 2.25e-63 202.0 COG3190@1|root,COG3190@2|Bacteria,1VGFI@1239|Firmicutes,4HJJQ@91061|Bacilli,1ZETY@1386|Bacillus 91061|Bacilli N Flagellar biosynthesis protein, FliO fliZ - - ko:K02418 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - FliO k141_12688_3 218284.CCDN010000001_gene1919 5.67e-160 459.0 COG1776@1|root,COG1886@1|root,COG1776@2|Bacteria,COG1886@2|Bacteria,1TPT8@1239|Firmicutes,4HC56@91061|Bacilli,1ZB7S@1386|Bacillus 91061|Bacilli N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation fliY GO:0003674,GO:0003824,GO:0004721,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006935,GO:0008150,GO:0008152,GO:0009605,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0032879,GO:0036211,GO:0040011,GO:0040012,GO:0042221,GO:0042330,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0050896,GO:0051270,GO:0065007,GO:0071704,GO:0140096,GO:1901564,GO:1902021,GO:2000145 - ko:K02417 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 - - CheC,FliMN_C k141_30184_1 1453501.JELR01000002_gene488 4.99e-79 242.0 COG3221@1|root,COG3221@2|Bacteria,1R5AU@1224|Proteobacteria,1RS4Z@1236|Gammaproteobacteria,4682S@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG3221 ABC-type phosphate phosphonate transport system, periplasmic component - - - - - - - - - - - - NMT1,Phosphonate-bd k141_33934_1 218284.CCDN010000001_gene1946 1.07e-16 77.8 COG2968@1|root,COG2968@2|Bacteria,1VB7C@1239|Firmicutes,4HH35@91061|Bacilli,1ZGZ6@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF541) bp26 - - ko:K09807 - - - - ko00000 - - - SIMPL k141_33934_2 218284.CCDN010000001_gene1945 1.55e-41 142.0 2C860@1|root,32RKH@2|Bacteria,1VATE@1239|Firmicutes,4HMZP@91061|Bacilli,1ZHVD@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_33934_3 866895.HBHAL_4261 1.04e-09 58.9 COG0039@1|root,COG0039@2|Bacteria,1TPSY@1239|Firmicutes,4HB0Z@91061|Bacilli,3NE46@45667|Halobacillus 91061|Bacilli C lactate/malate dehydrogenase, alpha/beta C-terminal domain ldh - 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 - R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 - - - Ldh_1_C,Ldh_1_N k141_17222_1 1117647.M5M_06505 2.88e-111 343.0 COG1629@1|root,COG4771@2|Bacteria,1MUNK@1224|Proteobacteria,1RN9S@1236|Gammaproteobacteria,1J59B@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_23307_1 1453501.JELR01000002_gene1539 4.54e-29 114.0 COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,1RM7S@1236|Gammaproteobacteria,4640S@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0739 Membrane proteins related to metalloendopeptidases yebA - - - - - - - - - - - OapA,OapA_N,Peptidase_M23 k141_23307_2 1453501.JELR01000002_gene1538 3.17e-81 250.0 COG2377@1|root,COG2377@2|Bacteria,1MV4E@1224|Proteobacteria,1RNTZ@1236|Gammaproteobacteria,464CU@72275|Alteromonadaceae 1236|Gammaproteobacteria O Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling anmK GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237 2.7.1.170 ko:K09001 - - - - ko00000,ko01000 - - iECABU_c1320.ECABU_c18930,iECED1_1282.ECED1_1841,ic_1306.c2032 AnmK k141_36162_1 218284.CCDN010000008_gene4223 2.92e-102 320.0 COG0849@1|root,COG0849@2|Bacteria,1TP1Z@1239|Firmicutes,4HBAG@91061|Bacilli,1ZBRW@1386|Bacillus 91061|Bacilli D Cell division protein FtsA ftsA_1 - - - - - - - - - - - FtsA,PilM_2 k141_24365_2 279010.BL00005 5.5e-53 177.0 2C5HJ@1|root,2Z812@2|Bacteria,1TQQ6@1239|Firmicutes,4HA3F@91061|Bacilli,1ZCGB@1386|Bacillus 91061|Bacilli S Tetraprenyl-beta-curcumene synthase ytpB - 4.2.3.130 ko:K16188 - - R10009 RC02994 ko00000,ko01000 - - - DUF2600 k141_12689_1 1089548.KI783301_gene3392 1.17e-13 64.3 2EMP1@1|root,33FBF@2|Bacteria,1VKRU@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - - k141_5488_1 1042377.AFPJ01000007_gene1864 2.8e-49 163.0 COG0665@1|root,COG0665@2|Bacteria,1RH7N@1224|Proteobacteria,1S9ZE@1236|Gammaproteobacteria,467V9@72275|Alteromonadaceae 1236|Gammaproteobacteria E tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity - - - - - - - - - - - - - k141_13897_1 42565.FP66_06360 4.68e-128 372.0 COG1017@1|root,COG1018@1|root,COG1017@2|Bacteria,COG1018@2|Bacteria,1MV41@1224|Proteobacteria,1RMPJ@1236|Gammaproteobacteria,1XIM4@135619|Oceanospirillales 135619|Oceanospirillales C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress hmp - 1.14.12.17 ko:K05916 ko05132,map05132 - - - ko00000,ko00001,ko01000 - - - FAD_binding_6,Globin,NAD_binding_1 k141_7676_1 1231057.AMGD01000024_gene2974 5.34e-72 241.0 COG1404@1|root,COG1404@2|Bacteria,1UZRQ@1239|Firmicutes,4HEVW@91061|Bacilli,26GVJ@186818|Planococcaceae 91061|Bacilli O Subtilase family - - - ko:K17734 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S8,SLH k141_22006_1 218284.CCDN010000001_gene1328 1.07e-20 90.9 COG5002@1|root,COG5002@2|Bacteria,1TPSK@1239|Firmicutes,4HAH5@91061|Bacilli,1ZB8J@1386|Bacillus 91061|Bacilli T Histidine kinase arlS GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 2.7.13.3 ko:K18940 ko02020,map02020 M00716,M00717 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA k141_22006_2 218284.CCDN010000001_gene1329 7.55e-67 207.0 2DR1M@1|root,339SJ@2|Bacteria,1VMD6@1239|Firmicutes,4HRV5@91061|Bacilli,1ZGEB@1386|Bacillus 91061|Bacilli S COG0071 Molecular chaperone (small heat shock protein) yozR - - - - - - - - - - - CS k141_4221_2 218284.CCDN010000001_gene1184 0.0 904.0 COG3039@1|root,COG3039@2|Bacteria,1TPFS@1239|Firmicutes,4H9V9@91061|Bacilli,1ZDIP@1386|Bacillus 91061|Bacilli L COG3666 Transposase and inactivated derivatives - - - - - - - - - - - - DDE_Tnp_1,DDE_Tnp_1_6,DUF772 k141_20748_3 218284.CCDN010000001_gene234 1.57e-89 264.0 COG0589@1|root,COG0589@2|Bacteria,1V3NY@1239|Firmicutes,4HIP3@91061|Bacilli,1ZGY4@1386|Bacillus 91061|Bacilli T Belongs to the universal stress protein A family uspA - - - - - - - - - - - Usp k141_29095_1 1071073.KI530543_gene3091 5.58e-17 81.3 COG1289@1|root,COG1289@2|Bacteria,1U18W@1239|Firmicutes,4IJPB@91061|Bacilli,1ZDV7@1386|Bacillus 91061|Bacilli S Fusaric acid resistance protein-like - - - - - - - - - - - - FUSC,FUSC_2 k141_19695_1 1123514.KB905899_gene447 4.12e-09 57.0 COG1509@1|root,COG1509@2|Bacteria,1MUPJ@1224|Proteobacteria,1RM84@1236|Gammaproteobacteria,45ZWU@72273|Thiotrichales 72273|Thiotrichales E TIGRFAM KamA family protein epmB - - ko:K19810 - - - - ko00000,ko01000,ko03012 - - - Fer4_12,Fer4_14,Radical_SAM k141_31381_1 1444310.JANV01000064_gene1971 3.57e-14 73.9 COG4972@1|root,COG4972@2|Bacteria,1TSTG@1239|Firmicutes,4HFQU@91061|Bacilli,1ZC5N@1386|Bacillus 91061|Bacilli NU COG4972 Tfp pilus assembly protein, ATPase PilM - - - ko:K02662,ko:K02663 - - - - ko00000,ko02035,ko02044 - - - PilM_2 k141_25711_2 1116375.VEJY3_20231 1.54e-33 115.0 2AVHZ@1|root,31MAI@2|Bacteria,1QJ5B@1224|Proteobacteria,1TH2V@1236|Gammaproteobacteria,1Y1ZV@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_25711_3 1116375.VEJY3_20241 8.04e-132 375.0 COG0625@1|root,COG0625@2|Bacteria,1Q05U@1224|Proteobacteria,1RZZS@1236|Gammaproteobacteria,1XVB1@135623|Vibrionales 135623|Vibrionales O Glutathione S-transferase - - - - - - - - - - - - GST_C,GST_C_2,GST_N_3 k141_25711_4 223926.28809353 2.46e-113 327.0 COG1309@1|root,COG1309@2|Bacteria,1N6WG@1224|Proteobacteria,1SCAJ@1236|Gammaproteobacteria,1XX70@135623|Vibrionales 135623|Vibrionales K Bacterial regulatory proteins, tetR family VVA0998 - - - - - - - - - - - TetR_N k141_24366_1 218284.CCDN010000001_gene1080 1.12e-46 156.0 COG1408@1|root,COG1408@2|Bacteria,1V494@1239|Firmicutes,4HH1B@91061|Bacilli,1ZBFW@1386|Bacillus 91061|Bacilli S Calcineurin-like phosphoesterase superfamily domain ypbG - - ko:K07098 - - - - ko00000 - - - Metallophos,Metallophos_2 k141_24366_2 218284.CCDN010000001_gene1079 1.96e-64 199.0 2E8AX@1|root,309PA@2|Bacteria,1U5FH@1239|Firmicutes,4IF70@91061|Bacilli,1ZKD7@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_24366_3 218284.CCDN010000001_gene1078 4.35e-05 44.3 COG0517@1|root,COG0517@2|Bacteria,1TR5G@1239|Firmicutes,4H9ZA@91061|Bacilli,1ZD7H@1386|Bacillus 91061|Bacilli S CBS domain - - - - - - - - - - - - CBS k141_5489_1 218284.CCDN010000001_gene737 1.06e-87 263.0 COG1385@1|root,COG1385@2|Bacteria,1V1CT@1239|Firmicutes,4HH8P@91061|Bacilli,1ZAV7@1386|Bacillus 91061|Bacilli J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit rsmE GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.193 ko:K09761 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_RNA k141_17225_1 1116375.VEJY3_08240 1.27e-92 271.0 COG4539@1|root,COG4539@2|Bacteria,1N1G8@1224|Proteobacteria,1S9FD@1236|Gammaproteobacteria,1XXHW@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF962) - - - - - - - - - - - - DUF962 k141_25712_1 42565.FP66_07640 5.36e-60 191.0 COG2894@1|root,COG2894@2|Bacteria,1MUEU@1224|Proteobacteria,1RNJ0@1236|Gammaproteobacteria,1XH74@135619|Oceanospirillales 135619|Oceanospirillales D Belongs to the ParA family minD - - ko:K03609 - - - - ko00000,ko03036,ko04812 - - - AAA_31,CbiA k141_25712_2 42565.FP66_07635 6.99e-38 127.0 COG0851@1|root,COG0851@2|Bacteria,1N6QD@1224|Proteobacteria,1SC8W@1236|Gammaproteobacteria,1XM7J@135619|Oceanospirillales 135619|Oceanospirillales D Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell minE - - ko:K03608 - - - - ko00000,ko03036,ko04812 - - - MinE k141_32596_1 1453501.JELR01000002_gene1372 1.45e-49 157.0 COG0695@1|root,COG0695@2|Bacteria,1N72P@1224|Proteobacteria,1SCA2@1236|Gammaproteobacteria,468F1@72275|Alteromonadaceae 1236|Gammaproteobacteria O Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins grxC - - ko:K03676 - - - - ko00000,ko03110 - - - Glutaredoxin k141_32596_2 1042377.AFPJ01000038_gene1108 9.9e-84 248.0 COG0607@1|root,COG0607@2|Bacteria,1MZ83@1224|Proteobacteria,1S8ZI@1236|Gammaproteobacteria,4680N@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0607 Rhodanese-related sulfurtransferase yibN GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.8.1.1,2.8.1.2 ko:K01011 ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122 - R01931,R03105,R03106 RC00214 ko00000,ko00001,ko01000 - - - Rhodanese k141_32596_3 1453501.JELR01000002_gene1370 2.28e-24 100.0 COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,1RMJE@1236|Gammaproteobacteria,465AD@72275|Alteromonadaceae 1236|Gammaproteobacteria G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate gpmI GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030145,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046537,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.4.2.12 ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000 - - iECSE_1348.ECSE_3895,iJN746.PP_5056 Metalloenzyme,Phosphodiest,iPGM_N k141_12721_1 1042377.AFPJ01000005_gene2463 1.01e-10 60.1 COG4665@1|root,COG4665@2|Bacteria,1RHBW@1224|Proteobacteria,1S5Y0@1236|Gammaproteobacteria,467SF@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Tripartite ATP-independent periplasmic transporters, DctQ component gtrA - - - - - - - - - - - DctQ k141_22024_1 218284.CCDN010000005_gene3246 2.19e-117 347.0 COG0534@1|root,COG0534@2|Bacteria,1TQMT@1239|Firmicutes,4H9Y2@91061|Bacilli,1ZBQK@1386|Bacillus 91061|Bacilli V Mate efflux family protein yisQ - - - - - - - - - - - MatE k141_9383_1 1042377.AFPJ01000004_gene414 5.96e-16 77.0 COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1MWCC@1224|Proteobacteria,1RNGC@1236|Gammaproteobacteria,465FU@72275|Alteromonadaceae 1236|Gammaproteobacteria K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon birA GO:0000166,GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004077,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009305,GO:0009374,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0017053,GO:0017076,GO:0017144,GO:0018130,GO:0018271,GO:0019538,GO:0019752,GO:0019842,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032991,GO:0033218,GO:0033293,GO:0034641,GO:0035639,GO:0036094,GO:0036211,GO:0042364,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043565,GO:0043603,GO:0043604,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681,GO:1990837 6.3.4.15 ko:K03524 ko00780,ko01100,map00780,map01100 - R01074,R05145 RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko01000,ko03000 - - - BPL_C,BPL_LplA_LipB,HTH_11 k141_9383_2 1122951.ATUE01000001_gene524 6.49e-20 92.0 COG1521@1|root,COG1521@2|Bacteria,1MUYA@1224|Proteobacteria,1S99V@1236|Gammaproteobacteria,3NJKW@468|Moraxellaceae 1236|Gammaproteobacteria F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis coaX - 2.7.1.33 ko:K03525 ko00770,ko01100,map00770,map01100 M00120 R02971,R03018,R04391 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Pan_kinase k141_34198_1 441769.ABFU01000028_gene1101 8.85e-117 349.0 COG1108@1|root,COG1108@2|Bacteria,1TPZB@1239|Firmicutes,4HCDH@91061|Bacilli,1ZDBC@1386|Bacillus 91061|Bacilli P COG1108 ABC-type Mn2 Zn2 transport systems, permease components mntC GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0010035,GO:0010038,GO:0010043,GO:0016020,GO:0042221,GO:0044464,GO:0050896,GO:0071944 - ko:K11705,ko:K11708,ko:K19976 ko02010,map02010 M00318,M00319,M00792 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15,3.A.1.15.15,3.A.1.15.6 - - ABC-3 k141_10456_2 218284.CCDN010000002_gene2159 5.99e-169 475.0 COG1175@1|root,COG1175@2|Bacteria,1TS63@1239|Firmicutes,4HECA@91061|Bacilli,1ZBSI@1386|Bacillus 91061|Bacilli G Binding-protein-dependent transport system inner membrane component - - - ko:K02025 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - BPD_transp_1 k141_19974_1 1279017.AQYJ01000021_gene2856 2.06e-198 563.0 COG0738@1|root,COG0738@2|Bacteria,1MXDC@1224|Proteobacteria,1RQX9@1236|Gammaproteobacteria,4659F@72275|Alteromonadaceae 1236|Gammaproteobacteria G Major Facilitator Superfamily gluP - - ko:K02429 - - - - ko00000,ko02000 2.A.1.7 - - MFS_1 k141_19974_2 864051.BurJ1DRAFT_1450 2.07e-38 142.0 COG0837@1|root,COG0837@2|Bacteria,1MVFI@1224|Proteobacteria,2VH5F@28216|Betaproteobacteria,1KK56@119065|unclassified Burkholderiales 28216|Betaproteobacteria F Belongs to the bacterial glucokinase family glk - 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Glucokinase,HTH_6,SIS k141_22384_1 218284.CCDN010000001_gene1013 4.72e-86 259.0 COG0345@1|root,COG0345@2|Bacteria,1TP1E@1239|Firmicutes,4H9RV@91061|Bacilli,1ZCWZ@1386|Bacillus 91061|Bacilli E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline proC - 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 - - - F420_oxidored,P5CR_dimer k141_36365_1 218284.CCDN010000006_gene3725 9.65e-81 250.0 COG3320@1|root,COG3320@2|Bacteria,1TQPW@1239|Firmicutes,4HAFC@91061|Bacilli,1ZCU0@1386|Bacillus 91061|Bacilli Q Male sterility protein - - - - - - - - - - - - NAD_binding_4 k141_29369_1 1453501.JELR01000001_gene3130 6.67e-127 365.0 COG1428@1|root,COG1428@2|Bacteria,1RC50@1224|Proteobacteria,1RRXT@1236|Gammaproteobacteria,464II@72275|Alteromonadaceae 1236|Gammaproteobacteria F Deoxynucleoside kinase dgk - - - - - - - - - - - dNK k141_30371_1 218284.CCDN010000005_gene3228 6.83e-163 489.0 COG3857@1|root,COG3857@2|Bacteria,1TQJW@1239|Firmicutes,4HAY6@91061|Bacilli,1ZC70@1386|Bacillus 91061|Bacilli L ATP-dependent helicase deoxyribonuclease subunit B rexB GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0004527,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.6.4.12 ko:K16899 - - - - ko00000,ko01000,ko03400 - - - Exonuc_V_gamma,PDDEXK_1,UvrD_C k141_20955_1 935837.JAEK01000004_gene4693 5.55e-119 351.0 COG0719@1|root,COG0719@2|Bacteria,1TRT0@1239|Firmicutes,4HB6W@91061|Bacilli,1ZATY@1386|Bacillus 91061|Bacilli O assembly protein SufD sufD - - ko:K07033,ko:K09015 - - - - ko00000 - - - UPF0051 k141_16318_1 1042377.AFPJ01000030_gene508 6.8e-105 316.0 COG0226@1|root,COG2885@1|root,COG0226@2|Bacteria,COG2885@2|Bacteria,1MVXP@1224|Proteobacteria,1RNK7@1236|Gammaproteobacteria,46D11@72275|Alteromonadaceae 1236|Gammaproteobacteria MP PBP superfamily domain pstS - - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - OmpA,PBP_like_2 k141_29370_1 1294265.JCM21738_2444 2.5e-50 167.0 COG2208@1|root,COG2208@2|Bacteria,1TQY5@1239|Firmicutes,4HAF6@91061|Bacilli,1ZBIB@1386|Bacillus 91061|Bacilli KT phosphatase rsbU - 3.1.3.3 ko:K07315 - - - - ko00000,ko01000,ko03021 - - - RsbU_N,SpoIIE k141_29370_2 1294265.JCM21738_2445 3.68e-69 209.0 COG1366@1|root,COG1366@2|Bacteria,1V8XY@1239|Firmicutes,4HK7Y@91061|Bacilli,1ZQUJ@1386|Bacillus 91061|Bacilli T STAS domain - - - ko:K04749 - - - - ko00000,ko03021 - - - STAS,STAS_2 k141_22385_1 1042377.AFPJ01000037_gene2997 1.97e-07 52.4 COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,1RMGN@1236|Gammaproteobacteria,463XZ@72275|Alteromonadaceae 1236|Gammaproteobacteria E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate trpA - 4.2.1.20 ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - Trp_syntA k141_15093_1 1294265.JCM21738_4903 5.67e-45 159.0 COG1033@1|root,COG1033@2|Bacteria,1VSWA@1239|Firmicutes,4HHPY@91061|Bacilli,1ZIDI@1386|Bacillus 91061|Bacilli S MMPL family - - - ko:K07003 - - - - ko00000 - - - MMPL k141_15093_2 1294265.JCM21738_5161 1.42e-46 160.0 COG1292@1|root,COG1292@2|Bacteria,1TRS6@1239|Firmicutes,4HA7U@91061|Bacilli,1ZBRN@1386|Bacillus 91061|Bacilli M Belongs to the BCCT transporter (TC 2.A.15) family - - - ko:K05020 - - - - ko00000,ko02000 2.A.15.1.1,2.A.15.1.11 - - BCCT k141_1008_2 1453501.JELR01000002_gene1433 0.0 1192.0 COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,1RMNZ@1236|Gammaproteobacteria,4641P@72275|Alteromonadaceae 1236|Gammaproteobacteria I Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA acsA - 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACAS_N,AMP-binding,AMP-binding_C k141_1008_4 1042377.AFPJ01000043_gene859 6.61e-79 235.0 COG0853@1|root,COG0853@2|Bacteria,1RI1B@1224|Proteobacteria,1S66E@1236|Gammaproteobacteria,46727@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine panD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0010467,GO:0016485,GO:0016540,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0051604,GO:0071704,GO:1901564 4.1.1.11 ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 M00119 R00489 RC00299 ko00000,ko00001,ko00002,ko01000 - - iECP_1309.ECP_0139,iYL1228.KPN_00139 Asp_decarbox k141_1008_6 1279017.AQYJ01000020_gene1345 1.8e-38 141.0 2DBDT@1|root,2Z8NY@2|Bacteria,1N7S2@1224|Proteobacteria,1RTZE@1236|Gammaproteobacteria,46D1R@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_1008_9 1279017.AQYJ01000020_gene1348 1.57e-262 722.0 COG0019@1|root,COG0019@2|Bacteria,1MW3T@1224|Proteobacteria,1RP8C@1236|Gammaproteobacteria,463ZW@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the Orn Lys Arg decarboxylase class-II family. NspC subfamily nspC GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0019842,GO:0030170,GO:0034641,GO:0036094,GO:0042401,GO:0042710,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0044010,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044764,GO:0045312,GO:0046204,GO:0046983,GO:0048037,GO:0050662,GO:0051704,GO:0070279,GO:0071704,GO:0097159,GO:0097164,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.1.1.96 ko:K13747 ko00330,ko01100,map00330,map01100 - R09081,R09082 RC00299 ko00000,ko00001,ko01000 - - - Orn_DAP_Arg_deC k141_1008_10 1453501.JELR01000002_gene1416 2.01e-185 518.0 COG0010@1|root,COG0010@2|Bacteria,1MVFH@1224|Proteobacteria,1RMH5@1236|Gammaproteobacteria,4689W@72275|Alteromonadaceae 1236|Gammaproteobacteria E Arginase family speB GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008783,GO:0009058,GO:0009308,GO:0009309,GO:0009445,GO:0009446,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0030145,GO:0034641,GO:0042401,GO:0043167,GO:0043169,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.1,3.5.3.11,3.5.3.17,3.5.3.7,3.5.3.8 ko:K01476,ko:K01479,ko:K01480,ko:K12255,ko:K18459 ko00220,ko00330,ko00340,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map00340,map01100,map01110,map01130,map01230,map05146 M00029,M00045,M00133,M00134 R00551,R01157,R01990,R02285 RC00024,RC00221,RC00329,RC00681 ko00000,ko00001,ko00002,ko01000 - - iB21_1397.B21_02730,iECB_1328.ECB_02767,iECD_1391.ECD_02767,iSbBS512_1146.SbBS512_E3370 Arginase k141_1008_11 1279017.AQYJ01000020_gene1350 1.01e-43 153.0 2DBQ1@1|root,2ZABN@2|Bacteria,1R83J@1224|Proteobacteria,1T169@1236|Gammaproteobacteria,46BUW@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_1008_14 1453501.JELR01000002_gene884 3.06e-127 370.0 2BFY8@1|root,329TX@2|Bacteria,1R582@1224|Proteobacteria,1S61M@1236|Gammaproteobacteria,467SZ@72275|Alteromonadaceae 1236|Gammaproteobacteria S Membrane - - - - - - - - - - - - - k141_1008_15 1279017.AQYJ01000020_gene1355 9.91e-47 150.0 COG0238@1|root,COG0238@2|Bacteria,1MZ8U@1224|Proteobacteria,1S8R8@1236|Gammaproteobacteria,467T8@72275|Alteromonadaceae 1236|Gammaproteobacteria J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit rpsR GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048027,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02963 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S18 k141_1008_17 523791.Kkor_0188 5.13e-80 247.0 COG3751@1|root,COG3751@2|Bacteria,1RBXB@1224|Proteobacteria,1RR8W@1236|Gammaproteobacteria 1236|Gammaproteobacteria O SMART Prolyl 4-hydroxylase, alpha subunit - - - - - - - - - - - - 2OG-FeII_Oxy_3 k141_1008_18 1279017.AQYJ01000020_gene1364 4.1e-151 428.0 COG0566@1|root,COG0566@2|Bacteria,1MWCM@1224|Proteobacteria,1RN2F@1236|Gammaproteobacteria,4640C@72275|Alteromonadaceae 1236|Gammaproteobacteria J Specifically methylates the ribose of guanosine 2251 in 23S rRNA rlmB GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 ko:K03218 - - - - ko00000,ko01000,ko03009 - - - SpoU_methylase,SpoU_sub_bind k141_1008_19 1279017.AQYJ01000020_gene1365 0.0 1070.0 COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,1RMQE@1236|Gammaproteobacteria,464C0@72275|Alteromonadaceae 1236|Gammaproteobacteria J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs rnr GO:0000175,GO:0003674,GO:0003724,GO:0003824,GO:0004386,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008408,GO:0008997,GO:0009056,GO:0009057,GO:0009266,GO:0009409,GO:0009628,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016896,GO:0017111,GO:0019222,GO:0019439,GO:0034458,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - ko:K12573 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03016,ko03019 - - - HTH_12,OB_RNB,RNB,S1 k141_10457_1 56780.SYN_01596 2.74e-69 218.0 COG0024@1|root,COG0024@2|Bacteria,1MU99@1224|Proteobacteria,42MM5@68525|delta/epsilon subdivisions,2WJMN@28221|Deltaproteobacteria,2MQB2@213462|Syntrophobacterales 28221|Deltaproteobacteria J TIGRFAM methionine aminopeptidase, type I map - 3.4.11.18 ko:K01265 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M24 k141_9385_2 42565.FP66_06980 1.78e-05 43.5 COG3630@1|root,COG3630@2|Bacteria,1NHYS@1224|Proteobacteria,1SGS8@1236|Gammaproteobacteria,1XM8S@135619|Oceanospirillales 135619|Oceanospirillales C Lyase and sodium transporter oadG - 4.1.1.3 ko:K01573 ko00620,ko01100,map00620,map01100 - R00217 RC00040 ko00000,ko00001,ko01000,ko02000 3.B.1.1.1 - - OAD_gamma k141_22386_1 218284.CCDN010000001_gene1038 1.12e-137 394.0 COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,4HAEX@91061|Bacilli,1ZDBF@1386|Bacillus 91061|Bacilli L recombinase XerD xerD - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase k141_1009_2 1453501.JELR01000001_gene2192 1.26e-12 65.1 COG0500@1|root,COG0500@2|Bacteria,1RAE4@1224|Proteobacteria,1S0RC@1236|Gammaproteobacteria,466UC@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family tpm - 2.1.1.67 ko:K00569 ko00983,map00983 - R08236,R08239,R08246 RC00003,RC00980,RC02277 ko00000,ko00001,ko01000 - - - TPMT k141_1915_1 1238450.VIBNISOn1_p0011 1.18e-84 258.0 COG0583@1|root,COG0583@2|Bacteria,1NQJW@1224|Proteobacteria,1SM2Q@1236|Gammaproteobacteria,1XWEM@135623|Vibrionales 135623|Vibrionales K Bacterial regulatory helix-turn-helix protein, lysR family - - - - - - - - - - - - HTH_1,LysR_substrate k141_1915_2 29495.EA26_13995 5.41e-125 359.0 COG0625@1|root,COG0625@2|Bacteria,1MWY4@1224|Proteobacteria,1S8DJ@1236|Gammaproteobacteria,1Y2KP@135623|Vibrionales 135623|Vibrionales O Glutathione S-transferase, C-terminal domain - - - - - - - - - - - - GST_C,GST_N k141_1915_3 1116375.VEJY3_19196 8.71e-91 270.0 COG1670@1|root,COG1670@2|Bacteria,1N3MY@1224|Proteobacteria,1THSM@1236|Gammaproteobacteria,1XXEI@135623|Vibrionales 135623|Vibrionales J Acetyltransferase (GNAT) domain - - - ko:K03817 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 k141_1915_4 1116375.VEJY3_19191 1.34e-94 276.0 COG0494@1|root,COG0494@2|Bacteria,1RKVK@1224|Proteobacteria,1S86R@1236|Gammaproteobacteria,1XX6U@135623|Vibrionales 135623|Vibrionales L NUDIX domain - - 3.6.1.67 ko:K08310 ko00790,map00790 M00126 R04638 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NUDIX k141_36367_1 218284.CCDN010000010_gene4391 6.75e-168 473.0 COG4956@1|root,COG4956@2|Bacteria,1TP0P@1239|Firmicutes,4H9NQ@91061|Bacilli,1ZB5A@1386|Bacillus 91061|Bacilli S COG4956 Integral membrane protein (PIN domain superfamily) yacL GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - - - - - - - - - - TRAM k141_29371_1 351607.Acel_1903 9.32e-31 117.0 COG1573@1|root,COG1573@2|Bacteria,2GK1I@201174|Actinobacteria,4ERCZ@85013|Frankiales 201174|Actinobacteria L uracil-DNA glycosylase udgB GO:0003674,GO:0003824,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033958,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051540,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG k141_29371_2 1122621.ATZA01000030_gene2735 3.52e-20 89.4 COG1607@1|root,COG1607@2|Bacteria,4NERA@976|Bacteroidetes,1IS80@117747|Sphingobacteriia 976|Bacteroidetes I PFAM thioesterase superfamily - - - - - - - - - - - - 4HBT k141_29371_3 518766.Rmar_1303 1.11e-68 223.0 COG1012@1|root,COG1012@2|Bacteria,4NEB7@976|Bacteroidetes,1FINT@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes C Belongs to the aldehyde dehydrogenase family mmsA - 1.2.1.18,1.2.1.27 ko:K00140,ko:K22187 ko00040,ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00040,map00280,map00410,map00562,map00640,map01100,map01200 M00013 R00705,R00706,R00922,R00935,R11768 RC00004,RC00080,RC02723,RC02817 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_22387_2 388413.ALPR1_00675 1.58e-34 133.0 COG5276@1|root,COG5276@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Big_2,DUF1566,LVIVD,Pec_lyase_C,Pectinesterase k141_16319_1 626887.J057_15155 2e-63 203.0 COG1319@1|root,COG1319@2|Bacteria,1MVJS@1224|Proteobacteria,1RY6A@1236|Gammaproteobacteria,465GM@72275|Alteromonadaceae 1236|Gammaproteobacteria C Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM yagS GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.17.1.4 ko:K11178 ko00230,ko01100,ko01120,map00230,map01100,map01120 M00546 R01768,R02103 RC00143 ko00000,ko00001,ko00002,ko01000 - - - CO_deh_flav_C,FAD_binding_5 k141_16319_2 1246995.AFR_34800 7.26e-78 236.0 COG2080@1|root,COG2080@2|Bacteria,2GMYH@201174|Actinobacteria,4DEFK@85008|Micromonosporales 201174|Actinobacteria C [2Fe-2S] binding domain xdhC - - ko:K13483 ko00230,ko01100,ko01120,map00230,map01100,map01120 M00546 R01768,R02103 RC00143 ko00000,ko00001,ko00002 - - - Fer2,Fer2_2 k141_37592_2 218284.CCDN010000003_gene3008 1.98e-191 535.0 COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,4HAMU@91061|Bacilli,1ZBC7@1386|Bacillus 91061|Bacilli E Belongs to the cysteine synthase cystathionine beta- synthase family cysK GO:0000096,GO:0000097,GO:0000098,GO:0003674,GO:0003824,GO:0004122,GO:0004124,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006555,GO:0006563,GO:0006790,GO:0006807,GO:0008134,GO:0008144,GO:0008150,GO:0008152,GO:0008284,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009070,GO:0009087,GO:0009987,GO:0016043,GO:0016053,GO:0016054,GO:0016740,GO:0016765,GO:0016829,GO:0016835,GO:0016836,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0022607,GO:0030170,GO:0032991,GO:0032993,GO:0036094,GO:0042127,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043388,GO:0043436,GO:0043933,GO:0044085,GO:0044093,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046395,GO:0046983,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0051098,GO:0051099,GO:0051101,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051291,GO:0065003,GO:0065007,GO:0065009,GO:0070279,GO:0071704,GO:0071840,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1904796,GO:1904798,GO:2000677,GO:2000679 2.5.1.47 ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03601,R04859 RC00020,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 - - - PALP k141_19980_1 218284.CCDN010000001_gene811 4.37e-95 282.0 COG0491@1|root,COG0491@2|Bacteria,1V6FA@1239|Firmicutes,4HHRQ@91061|Bacilli,1ZC72@1386|Bacillus 91061|Bacilli S COG0491 Zn-dependent hydrolases, including glyoxylases yqgX - 3.1.2.6 ko:K01069 ko00620,map00620 - R01736 RC00004,RC00137 ko00000,ko00001,ko01000 - - - Lactamase_B k141_12919_2 1453501.JELR01000001_gene2946 6.09e-267 741.0 COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,1RNM1@1236|Gammaproteobacteria,463YZ@72275|Alteromonadaceae 1236|Gammaproteobacteria E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides pepA GO:0001073,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004177,GO:0005488,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006351,GO:0006355,GO:0006508,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009056,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016787,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019538,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042150,GO:0043170,GO:0043171,GO:0043244,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140096,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1903506,GO:2000112,GO:2001141 3.4.11.1 ko:K01255 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - Peptidase_M17,Peptidase_M17_N k141_12919_3 765914.ThisiDRAFT_0008 1.73e-17 79.7 COG2927@1|root,COG2927@2|Bacteria 2|Bacteria L positive regulation of DNA-dependent DNA replication initiation holC GO:0005575,GO:0005622,GO:0005623,GO:0006275,GO:0008150,GO:0009314,GO:0009360,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010556,GO:0010557,GO:0010604,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032298,GO:0032991,GO:0042575,GO:0043846,GO:0043847,GO:0044424,GO:0044464,GO:0045740,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051054,GO:0051171,GO:0051173,GO:0060255,GO:0061695,GO:0065007,GO:0080090,GO:0090329,GO:1902494,GO:1990234,GO:2000105,GO:2000112 2.7.7.7 ko:K02339 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_chi k141_4386_1 1282356.H045_20095 3.32e-67 233.0 COG1961@1|root,COG1961@2|Bacteria,1N6DV@1224|Proteobacteria,1RYWS@1236|Gammaproteobacteria,1YUC9@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria L Recombinase zinc beta ribbon domain ybcK - - - - - - - - - - - Recombinase,Resolvase,Zn_ribbon_recom k141_4386_4 637910.ROD_20501 9.76e-111 343.0 28N3H@1|root,2ZB96@2|Bacteria,1R9U8@1224|Proteobacteria,1S2F3@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF2971) - - - - - - - - - - - - DUF2971 k141_4386_6 674977.VMC_08600 1.69e-09 58.9 COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,1RMB9@1236|Gammaproteobacteria,1XTCR@135623|Vibrionales 135623|Vibrionales O ATPase with chaperone activity comM - - ko:K07391 - - - - ko00000 - - - ChlI,Mg_chelatase,Mg_chelatase_C k141_6988_1 1231057.AMGD01000066_gene1123 4.03e-117 348.0 COG1966@1|root,COG1966@2|Bacteria,1TQN8@1239|Firmicutes,4H9SU@91061|Bacilli,26EFX@186818|Planococcaceae 91061|Bacilli T 5TM C-terminal transporter carbon starvation CstA cstA - - - - - - - - - - - CstA,CstA_5TM k141_36368_1 218284.CCDN010000001_gene1795 2.8e-135 393.0 COG0174@1|root,COG0174@2|Bacteria,1TNZA@1239|Firmicutes,4HACE@91061|Bacilli,1ZBIQ@1386|Bacillus 91061|Bacilli E glutamine synthetase glnA GO:0003674,GO:0005488,GO:0005515,GO:0006082,GO:0006355,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0006808,GO:0007154,GO:0007584,GO:0008134,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009605,GO:0009719,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016053,GO:0016597,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043392,GO:0043436,GO:0043562,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0045892,GO:0045934,GO:0046394,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051098,GO:0051100,GO:0051101,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0061984,GO:0065007,GO:0065009,GO:0070406,GO:0070887,GO:0071310,GO:0071417,GO:0071495,GO:0071496,GO:0071704,GO:0080090,GO:0090293,GO:0090295,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901698,GO:1901699,GO:1902679,GO:1903506,GO:1903507,GO:1904796,GO:1904797,GO:2000112,GO:2000113,GO:2000677,GO:2000678,GO:2001141 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C,Gln-synt_N k141_29372_1 1279017.AQYJ01000023_gene3092 3.29e-109 335.0 COG0620@1|root,COG0620@2|Bacteria,1MUI9@1224|Proteobacteria,1RMBA@1236|Gammaproteobacteria,465YA@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation metE GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0032259,GO:0034641,GO:0035999,GO:0036211,GO:0042084,GO:0042085,GO:0042558,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0050667,GO:0051186,GO:0071704,GO:0140096,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - iE2348C_1286.E2348C_4130,iECO103_1326.ECO103_4334,iECO111_1330.ECO111_4657,iECO26_1355.ECO26_4756,iECW_1372.ECW_m4131,iEKO11_1354.EKO11_4528,iPC815.YPO3788,iWFL_1372.ECW_m4131 Meth_synt_1,Meth_synt_2 k141_19009_3 218284.CCDN010000001_gene1177 3.58e-94 276.0 COG1963@1|root,COG1963@2|Bacteria,1V1NT@1239|Firmicutes,4HGII@91061|Bacilli,1ZRRS@1386|Bacillus 91061|Bacilli S Divergent PAP2 family - - - ko:K09775 - - - - ko00000 - - - DUF212 k141_26012_1 218284.CCDN010000001_gene1497 8.4e-225 625.0 COG2843@1|root,COG2843@2|Bacteria,1UZW4@1239|Firmicutes,4HB06@91061|Bacilli,1ZCM3@1386|Bacillus 91061|Bacilli M Bacterial capsule synthesis protein PGA_cap capA - - ko:K07282 - - - - ko00000 - - - PGA_cap k141_11783_1 1131730.BAVI_03314 3.91e-52 175.0 COG0451@1|root,COG0451@2|Bacteria,1TR3K@1239|Firmicutes,4HD3P@91061|Bacilli,1ZDCB@1386|Bacillus 91061|Bacilli GM NAD-dependent epimerase dehydratase - - 1.3.1.45 ko:K05281 ko00943,ko01110,map00943,map01110 - R06562,R06563,R07747,R07751 RC00805 ko00000,ko00001,ko01000 - - - Epimerase k141_1941_1 218284.CCDN010000004_gene3134 3.08e-116 352.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,1ZBIW@1386|Bacillus 91061|Bacilli V COG1132 ABC-type multidrug transport system, ATPase and permease components yheH GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702 - ko:K18217,ko:K18890 ko02010,map02010 M00635,M00707 - - ko00000,ko00001,ko00002,ko01504,ko02000 3.A.1,3.A.1.106.13,3.A.1.106.5 - - ABC_membrane,ABC_tran k141_34217_1 218284.CCDN010000009_gene4276 9.19e-302 825.0 COG1109@1|root,COG1109@2|Bacteria,1TP1X@1239|Firmicutes,4HB16@91061|Bacilli,1ZC74@1386|Bacillus 91061|Bacilli G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate glmM - 5.4.2.10 ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 - R02060 RC00408 ko00000,ko00001,ko01000 - - iSB619.SA_RS11275 PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV k141_1048_1 1408303.JNJJ01000038_gene9 9.65e-40 135.0 COG2868@1|root,COG2868@2|Bacteria,1VEQ9@1239|Firmicutes,4HNMV@91061|Bacilli,1ZI1F@1386|Bacillus 91061|Bacilli J ribosomal protein ysxB - - ko:K07584 - - - - ko00000 - - - Peptidase_Prp k141_12945_2 265729.GS18_0202880 1.49e-21 89.4 COG0603@1|root,COG0603@2|Bacteria,1TP4Z@1239|Firmicutes,4HB1Y@91061|Bacilli,1ZCJD@1386|Bacillus 91061|Bacilli F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) queC - 6.3.4.20 ko:K06920 ko00790,ko01100,map00790,map01100 - R09978 RC00959 ko00000,ko00001,ko01000,ko03016 - - - QueC k141_7014_1 1279017.AQYJ01000022_gene2604 2.14e-87 273.0 COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,1RMGS@1236|Gammaproteobacteria,46625@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II alkK - 6.2.1.44 ko:K20034 ko00920,map00920 - R10820 RC00004,RC00014 ko00000,ko00001,ko01000 - - - AMP-binding,AMP-binding_C k141_15096_1 1116375.VEJY3_15956 1.95e-141 422.0 COG3325@1|root,COG3979@1|root,COG3325@2|Bacteria,COG3979@2|Bacteria,1MWAR@1224|Proteobacteria,1RPNS@1236|Gammaproteobacteria,1XT0T@135623|Vibrionales 135623|Vibrionales G COG3325 Chitinase chiA - 3.2.1.14 ko:K01183 ko00520,ko01100,map00520,map01100 - R01206,R02334 RC00467 ko00000,ko00001,ko01000 - GH18 - CBM_5_12,ChitinaseA_N,Glyco_hydro_18,REJ k141_15096_2 223926.28808194 1.37e-79 240.0 2AWAY@1|root,31N6J@2|Bacteria,1QJXU@1224|Proteobacteria,1TI00@1236|Gammaproteobacteria,1XY1V@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF2850) - - - - - - - - - - - - DUF2850 k141_15096_3 1116375.VEJY3_15961 2.23e-58 181.0 COG3123@1|root,COG3123@2|Bacteria,1MZ8N@1224|Proteobacteria,1S9G3@1236|Gammaproteobacteria,1XYA2@135623|Vibrionales 135623|Vibrionales S Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions ppnP - 2.4.2.1,2.4.2.2 ko:K09913 ko00230,ko00240,map00230,map00240 - R01561,R01570,R01863,R01876,R02147,R02296,R02297 RC00063,RC00122 ko00000,ko00001,ko01000 - - - DUF1255 k141_15096_4 1280001.BAOA01000030_gene5189 4.46e-35 122.0 2AWP3@1|root,31NK0@2|Bacteria,1QKAN@1224|Proteobacteria,1TIE6@1236|Gammaproteobacteria,1XYYR@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_15096_5 1116375.VEJY3_15971 2.49e-205 576.0 COG2199@1|root,COG2199@2|Bacteria,1QTT5@1224|Proteobacteria,1SZCC@1236|Gammaproteobacteria,1Y2UY@135623|Vibrionales 135623|Vibrionales T COG2199 FOG GGDEF domain - - - - - - - - - - - - GGDEF k141_15096_7 675816.VIA_000715 8.33e-293 801.0 COG4580@1|root,COG4580@2|Bacteria,1MX1A@1224|Proteobacteria,1RRWC@1236|Gammaproteobacteria,1Y28D@135623|Vibrionales 135623|Vibrionales G LamB porin VVA0122 - - ko:K02024 - - - - ko00000,ko02000 1.B.3.1.1 - - LamB k141_15096_8 1280001.BAOA01000030_gene5186 3.15e-229 632.0 COG1609@1|root,COG1609@2|Bacteria,1MU1G@1224|Proteobacteria,1RMSP@1236|Gammaproteobacteria,1XTZQ@135623|Vibrionales 135623|Vibrionales K transcriptional regulators - - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 k141_15096_9 1280001.BAOA01000030_gene5185 1.53e-269 741.0 COG1653@1|root,COG1653@2|Bacteria,1PCRV@1224|Proteobacteria,1RYNV@1236|Gammaproteobacteria,1XSVV@135623|Vibrionales 135623|Vibrionales G ABC-type sugar transport system, periplasmic component - - - ko:K02027 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - SBP_bac_8 k141_15096_10 1051646.VITU9109_20671 5.08e-236 649.0 COG1175@1|root,COG1175@2|Bacteria,1R854@1224|Proteobacteria,1S0N0@1236|Gammaproteobacteria,1XTV6@135623|Vibrionales 135623|Vibrionales P ABC-type sugar transport systems, permease - - - ko:K02025 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - BPD_transp_1 k141_15096_11 1280001.BAOA01000030_gene5183 1.75e-198 551.0 COG0395@1|root,COG0395@2|Bacteria,1R4Q1@1224|Proteobacteria,1RPKD@1236|Gammaproteobacteria,1XUM6@135623|Vibrionales 135623|Vibrionales P transport system, permease component - - - ko:K02026,ko:K10119 ko02010,map02010 M00196,M00207 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.28 - - BPD_transp_1 k141_15096_12 1280001.BAOA01000030_gene5182 0.0 895.0 COG2723@1|root,COG2723@2|Bacteria,1MWG6@1224|Proteobacteria,1RMM2@1236|Gammaproteobacteria,1XSV6@135623|Vibrionales 135623|Vibrionales G Belongs to the glycosyl hydrolase 1 family - - 3.2.1.21,3.2.1.86 ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 - R00026,R00839,R02558,R02887,R02985,R03527,R04949,R04998,R05133,R05134,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - GT1 - Glyco_hydro_1 k141_15096_13 1280001.BAOA01000030_gene5181 2.39e-254 698.0 COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,1RM9E@1236|Gammaproteobacteria,1XSE0@135623|Vibrionales 135623|Vibrionales P Belongs to the ABC transporter superfamily - - - ko:K10112 ko02010,map02010 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1 - - ABC_tran k141_15096_14 1280001.BAOA01000264_gene3471 6.82e-214 594.0 COG1609@1|root,COG1609@2|Bacteria,1MVUR@1224|Proteobacteria,1RN2K@1236|Gammaproteobacteria,1XTVV@135623|Vibrionales 135623|Vibrionales K helix_turn _helix lactose operon repressor - - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 k141_15096_15 1116375.VEJY3_15976 1.27e-279 769.0 COG0534@1|root,COG0534@2|Bacteria,1MVRV@1224|Proteobacteria,1RNQ7@1236|Gammaproteobacteria,1XUCZ@135623|Vibrionales 135623|Vibrionales V Na driven multidrug efflux pump - - - - - - - - - - - - MatE k141_3220_1 218284.CCDN010000008_gene4183 2.85e-70 224.0 COG2610@1|root,COG2610@2|Bacteria,1TQJ6@1239|Firmicutes,4HA01@91061|Bacilli,1ZCGI@1386|Bacillus 91061|Bacilli EG COG2610 H gluconate symporter and related permeases - - - - - - - - - - - - CitMHS,GntP_permease k141_22421_1 218284.CCDN010000002_gene2063 7.5e-109 324.0 COG4129@1|root,COG4129@2|Bacteria,1UY2G@1239|Firmicutes,4HAWK@91061|Bacilli,1ZBAR@1386|Bacillus 91061|Bacilli S Aromatic acid exporter family member 1 - - - - - - - - - - - - ArAE_1 k141_15097_1 1121923.GPUN_1693 9.96e-92 277.0 COG2070@1|root,COG2070@2|Bacteria,1MWPC@1224|Proteobacteria,1RRA4@1236|Gammaproteobacteria,469BX@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG2070 Dioxygenases related to 2-nitropropane dioxygenase - - 1.13.12.16,1.3.1.9 ko:K00459,ko:K02371 ko00061,ko00910,ko01100,ko01212,map00061,map00910,map01100,map01212 M00083 R00025,R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765 RC00052,RC00076,RC02541,RC02759 ko00000,ko00001,ko00002,ko01000,ko01004 - - - NMO k141_5765_1 1294265.JCM21738_3340 7.4e-116 337.0 COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4HBB9@91061|Bacilli,1ZC1H@1386|Bacillus 91061|Bacilli EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components dppC - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1,OppC_N k141_9410_1 1131462.DCF50_p2564 2.17e-30 122.0 COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,248EM@186801|Clostridia,260FH@186807|Peptococcaceae 186801|Clostridia O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins dnaJ - - ko:K03686 - - - - ko00000,ko03029,ko03110 - - - DnaJ,DnaJ_C,DnaJ_CXXCXGXG k141_4405_1 1116375.VEJY3_01560 4.31e-41 147.0 COG1178@1|root,COG1178@2|Bacteria,1MWCF@1224|Proteobacteria,1RNHK@1236|Gammaproteobacteria,1XT1Z@135623|Vibrionales 135623|Vibrionales P COG1178 ABC-type Fe3 transport system, permease component thiP - - ko:K02063 ko02010,map02010 M00191 - - ko00000,ko00001,ko00002,ko02000 3.A.1.19 - - BPD_transp_1 k141_4405_2 223926.28805301 1.06e-144 410.0 COG3840@1|root,COG3840@2|Bacteria,1MV78@1224|Proteobacteria,1RQH3@1236|Gammaproteobacteria,1XU4J@135623|Vibrionales 135623|Vibrionales P Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system thiQ GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006855,GO:0008150,GO:0015234,GO:0015238,GO:0015399,GO:0015405,GO:0015888,GO:0015893,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0035461,GO:0042221,GO:0042493,GO:0042623,GO:0042626,GO:0043492,GO:0045117,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071934,GO:0072348,GO:0072531,GO:0090482,GO:1901474,GO:1901682 - ko:K02062 ko02010,map02010 M00191 - - ko00000,ko00001,ko00002,ko02000 3.A.1.19 - - ABC_tran k141_4405_3 1116375.VEJY3_01570 2.55e-90 265.0 COG0589@1|root,COG0589@2|Bacteria,1RI97@1224|Proteobacteria,1SAXI@1236|Gammaproteobacteria,1XX3J@135623|Vibrionales 135623|Vibrionales T Universal stress protein uspF - - - - - - - - - - - Usp k141_33292_2 218284.CCDN010000001_gene1924 1.88e-51 165.0 2E35U@1|root,32Y5R@2|Bacteria,1VEH9@1239|Firmicutes,4HMCM@91061|Bacilli,1ZQS3@1386|Bacillus 91061|Bacilli N Putative flagellar flg - - - - - - - - - - - Flagellar_put k141_3568_1 218284.CCDN010000001_gene144 1.33e-154 436.0 COG0483@1|root,COG0483@2|Bacteria,1TR4E@1239|Firmicutes,4HB92@91061|Bacilli,1ZAS1@1386|Bacillus 91061|Bacilli G Inositol monophosphatase suhB GO:0003674,GO:0003824,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 - - - Inositol_P k141_15458_1 1379281.AVAG01000108_gene241 1.34e-47 162.0 COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,42MWZ@68525|delta/epsilon subdivisions,2WJ2B@28221|Deltaproteobacteria,2M88A@213115|Desulfovibrionales 28221|Deltaproteobacteria J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis tuf - - ko:K02358 - - - - ko00000,ko03012,ko03029,ko04147 - - - GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 k141_32103_2 1347086.CCBA010000026_gene3185 2.81e-20 90.1 COG2386@1|root,COG2386@2|Bacteria,1VDEP@1239|Firmicutes,4HMK3@91061|Bacilli,1ZEI4@1386|Bacillus 91061|Bacilli O COG2386 ABC-type transport system involved in cytochrome c biogenesis, permease component - - - ko:K02194 ko02010,map02010 M00259 - - ko00000,ko00001,ko00002,ko02000 3.A.1.107 - - CcmB k141_10701_1 1453501.JELR01000002_gene385 6.71e-134 391.0 COG0715@1|root,COG0715@2|Bacteria,1MWDN@1224|Proteobacteria,1RPUP@1236|Gammaproteobacteria,46702@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components - - - ko:K22067 - - - - ko00000,ko02022 - - - NMT1_2 k141_10701_2 1042377.AFPJ01000022_gene1306 4.3e-20 85.5 COG3707@1|root,COG3707@2|Bacteria,1MXDV@1224|Proteobacteria,1S3YY@1236|Gammaproteobacteria,467KM@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG3707 Response regulator with nasT - - ko:K07183 - - - - ko00000,ko02022 - - - ANTAR,Response_reg k141_7135_1 1454004.AW11_01025 0.000953 41.2 COG0390@1|root,COG0390@2|Bacteria,1MV2N@1224|Proteobacteria,2VJX0@28216|Betaproteobacteria 28216|Betaproteobacteria S permease ybbM - - ko:K02069 - M00211 - - ko00000,ko00002,ko02000 9.B.25.1 - - UPF0014 k141_7135_2 1453501.JELR01000002_gene820 1.11e-73 224.0 COG1285@1|root,COG1285@2|Bacteria,1MURJ@1224|Proteobacteria,1S65I@1236|Gammaproteobacteria,467VV@72275|Alteromonadaceae 1236|Gammaproteobacteria S MgtC family - - - ko:K07507 - - - - ko00000,ko02000 9.B.20 - - MgtC k141_7135_3 1279017.AQYJ01000023_gene3216 1.31e-98 306.0 COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,1RN5I@1236|Gammaproteobacteria,469UF@72275|Alteromonadaceae 1236|Gammaproteobacteria C Aconitase C-terminal domain - - 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_C k141_14269_1 1116375.VEJY3_23591 9.1e-80 258.0 COG1289@1|root,COG1289@2|Bacteria,1QJEM@1224|Proteobacteria,1SMXK@1236|Gammaproteobacteria,1XUKV@135623|Vibrionales 135623|Vibrionales S Aromatic acid exporter family member 1 VPA1578 - - - - - - - - - - - FUSC k141_19024_1 218284.CCDN010000001_gene1953 8.36e-112 328.0 COG0673@1|root,COG0673@2|Bacteria,1TQSS@1239|Firmicutes,4HCIG@91061|Bacilli,1ZBUF@1386|Bacillus 91061|Bacilli S Oxidoreductase yulF GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0055114,GO:0102497 - ko:K22230 ko00562,ko01120,map00562,map01120 - R09954 RC00182 ko00000,ko00001,ko01000 - - - GFO_IDH_MocA k141_28536_1 234831.PSM_A0568 3.69e-27 108.0 COG1506@1|root,COG1506@2|Bacteria,1QWCQ@1224|Proteobacteria,1S38C@1236|Gammaproteobacteria,2Q3TM@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria E alpha/beta hydrolase fold - - - - - - - - - - - - Abhydrolase_3,Abhydrolase_6 k141_28536_2 1504981.KO116_2900 4.17e-78 241.0 2CDHC@1|root,32RXT@2|Bacteria,1N2M3@1224|Proteobacteria,1S6Z6@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_28536_3 1453501.JELR01000001_gene3103 6.08e-156 445.0 COG0656@1|root,COG0656@2|Bacteria,1MX6S@1224|Proteobacteria,1RQA1@1236|Gammaproteobacteria,466RA@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0656 Aldo keto reductases, related to diketogulonate reductase - - - - - - - - - - - - Aldo_ket_red k141_23781_1 218284.CCDN010000005_gene3375 1.55e-83 252.0 COG4359@1|root,COG4359@2|Bacteria,1TSZ9@1239|Firmicutes,4H9ZE@91061|Bacilli,1ZBXD@1386|Bacillus 91061|Bacilli E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene) mtnX - 3.1.3.87 ko:K08966 ko00270,ko01100,map00270,map01100 M00034 R07394 RC02074 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU13600 HAD k141_21404_1 330214.NIDE0901 6.86e-108 335.0 COG1271@1|root,COG1271@2|Bacteria 2|Bacteria C aerobic electron transport chain - - 1.10.3.14 ko:K00425,ko:K08738 ko00190,ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00190,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416 M00153,M00595 R10151,R11325 RC00061,RC03151,RC03152 ko00000,ko00001,ko00002,ko01000 3.D.4.3,3.D.4.6 - - Cyt_bd_oxida_I,Cytochrome_CBB3 k141_30914_1 234267.Acid_7338 9.14e-139 414.0 COG1228@1|root,COG1228@2|Bacteria,3Y39J@57723|Acidobacteria 57723|Acidobacteria Q Amidohydrolase family - - - - - - - - - - - - Amidohydro_1 k141_36859_1 1294265.JCM21738_309 1.65e-13 66.2 COG1580@1|root,COG1580@2|Bacteria,1V6K9@1239|Firmicutes,4HIJZ@91061|Bacilli,1ZI2U@1386|Bacillus 91061|Bacilli N Controls the rotational direction of flagella during chemotaxis fliL - - ko:K02415 - - - - ko00000,ko02035 - - - FliL k141_9513_1 218284.CCDN010000001_gene1816 5.82e-255 708.0 COG1953@1|root,COG1953@2|Bacteria,1TS5W@1239|Firmicutes,4HAIM@91061|Bacilli,1ZDNH@1386|Bacillus 91061|Bacilli FH COG1953 Cytosine uracil thiamine allantoin permeases pucI - - ko:K03457 - - - - ko00000 2.A.39 - - Transp_cyt_pur k141_7136_1 218284.CCDN010000006_gene3562 2.49e-45 157.0 COG0477@1|root,COG2814@2|Bacteria,1TQHD@1239|Firmicutes,4HBCZ@91061|Bacilli,1ZAUW@1386|Bacillus 91061|Bacilli EGP COG0477 Permeases of the major facilitator superfamily ywoG GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - - - - - - - - - - MFS_1,MFS_1_like,MFS_2,Sugar_tr k141_13081_1 218284.CCDN010000001_gene1054 3.21e-106 312.0 COG1354@1|root,COG1354@2|Bacteria,1TRW3@1239|Firmicutes,4HA6Q@91061|Bacilli,1ZDD6@1386|Bacillus 91061|Bacilli D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves scpA GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K05896 - - - - ko00000,ko03036 - - - SMC_ScpA k141_8328_1 1288826.MSNKSG1_14092 2.27e-44 153.0 COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,1RPNX@1236|Gammaproteobacteria,464T8@72275|Alteromonadaceae 1236|Gammaproteobacteria K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_3569_2 1415778.JQMM01000001_gene1294 5.58e-35 121.0 COG2212@1|root,COG2212@2|Bacteria,1N6VV@1224|Proteobacteria,1SE40@1236|Gammaproteobacteria,1J6KF@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P Multiple resistance and pH regulation protein F (MrpF / PhaF) mnhF - - ko:K05570 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - MrpF_PhaF k141_3569_3 1042377.AFPJ01000024_gene703 2.47e-37 130.0 COG1320@1|root,COG1320@2|Bacteria,1QTGI@1224|Proteobacteria,1RTH6@1236|Gammaproteobacteria,468PE@72275|Alteromonadaceae 1236|Gammaproteobacteria P Na+/H+ antiporter subunit - - - ko:K05571 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - PhaG_MnhG_YufB k141_33293_1 350688.Clos_2846 2.45e-56 185.0 COG2207@1|root,COG3708@1|root,COG2207@2|Bacteria,COG3708@2|Bacteria,1TPI9@1239|Firmicutes,2496K@186801|Clostridia,36EDW@31979|Clostridiaceae 186801|Clostridia K transcription activator, effector binding - - - ko:K13653 - - - - ko00000,ko03000 - - - GyrI-like,HTH_18 k141_5948_1 218284.CCDN010000001_gene986 6.31e-149 424.0 COG0022@1|root,COG0022@2|Bacteria,1TP3J@1239|Firmicutes,4HAP6@91061|Bacilli,1ZC0X@1386|Bacillus 91061|Bacilli C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit bfmBAB - 1.2.4.4 ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 M00036 R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00027,RC00627,RC02743,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU24040 Transket_pyr,Transketolase_C k141_10702_1 218284.CCDN010000002_gene2266 7.61e-140 407.0 COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,1TPXQ@1239|Firmicutes,4HA3C@91061|Bacilli,1ZBHE@1386|Bacillus 91061|Bacilli C Catalyzes the reversible hydration of fumarate to (S)- malate fumA - 4.2.1.2 ko:K01676 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - - Fumerase,Fumerase_C k141_17835_1 218284.CCDN010000001_gene180 4.38e-91 273.0 COG0730@1|root,COG0730@2|Bacteria,1TQBK@1239|Firmicutes,4HBCW@91061|Bacilli,1ZCK1@1386|Bacillus 91061|Bacilli S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE k141_34481_1 1121874.KB892379_gene228 1.67e-21 108.0 COG1404@1|root,COG3266@1|root,COG5492@1|root,COG1404@2|Bacteria,COG3266@2|Bacteria,COG5492@2|Bacteria,1TPH1@1239|Firmicutes,3VQWR@526524|Erysipelotrichia 526524|Erysipelotrichia O Fn3-like domain - - 3.4.21.96 ko:K01361 - - - - ko00000,ko01000,ko01002,ko03110 - - - FIVAR,Inhibitor_I9,PA,Peptidase_S8,fn3_5 k141_20214_1 218284.CCDN010000001_gene720 4.51e-87 265.0 COG0345@1|root,COG0345@2|Bacteria,1UZ3D@1239|Firmicutes,4HCJ6@91061|Bacilli,1ZBFA@1386|Bacillus 91061|Bacilli E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline comER - - ko:K02239 - M00429 - - ko00000,ko00002,ko02044 - - - F420_oxidored,P5CR_dimer k141_21405_2 218284.CCDN010000005_gene3464 2.86e-137 400.0 COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,4HAAI@91061|Bacilli,1ZBC5@1386|Bacillus 91061|Bacilli S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family - - - ko:K03308 - - - - ko00000 2.A.22.4,2.A.22.5 - - SNF k141_5949_1 1236973.JCM9157_2584 2.94e-87 272.0 COG0277@1|root,COG0277@2|Bacteria,1UIU4@1239|Firmicutes,4HBGZ@91061|Bacilli,1ZD7D@1386|Bacillus 91061|Bacilli C D-arabinono-1,4-lactone oxidase yitY - - - - - - - - - - - ALO,FAD_binding_4 k141_30915_1 218284.CCDN010000001_gene97 6.51e-193 546.0 COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,4HBK9@91061|Bacilli,1ZBHM@1386|Bacillus 91061|Bacilli I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) yngE - - - - - - - - - - iYO844.BSU18210 Carboxyl_trans k141_19025_2 665952.HMPREF1015_01930 3.27e-22 89.0 COG0695@1|root,COG0695@2|Bacteria 2|Bacteria O Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins XAC3035 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K06191 - - - - ko00000 - - - DUF836,Glutaredoxin k141_36860_1 1280001.BAOA01000027_gene4793 1.23e-111 328.0 COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,1RP4T@1236|Gammaproteobacteria,1XTFK@135623|Vibrionales 135623|Vibrionales E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily hisC GO:0000105,GO:0003674,GO:0003824,GO:0004400,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k141_1191_1 474922.ELA37803 5.19e-37 136.0 COG0163@1|root,2QWR5@2759|Eukaryota,38UIR@33154|Opisthokonta,3P1DG@4751|Fungi,3QTGF@4890|Ascomycota,219Q9@147550|Sordariomycetes 4751|Fungi H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for the ferulic acid decarboxylase FDC1. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN PAD1 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006725,GO:0006732,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009698,GO:0009803,GO:0009987,GO:0016054,GO:0016829,GO:0016830,GO:0016831,GO:0019439,GO:0019748,GO:0019752,GO:0032787,GO:0042537,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046271,GO:0046281,GO:0046395,GO:0051186,GO:0051188,GO:0071704,GO:0072329,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.5.1.129 ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 M00117 R01238,R02952,R03367,R04985,R04986,R11225 RC00391,RC00814,RC03392 ko00000,ko00001,ko00002,ko01000 - - iND750.YDR538W Flavoprotein k141_1191_2 1297570.MESS4_750192 1.4e-54 173.0 COG4319@1|root,COG4319@2|Bacteria,1N74E@1224|Proteobacteria,2UIZ8@28211|Alphaproteobacteria 28211|Alphaproteobacteria S ketosteroid isomerase - - - - - - - - - - - - SnoaL_2 k141_1191_3 765914.ThisiDRAFT_0109 4.39e-14 67.4 COG0607@1|root,32YCZ@2|Bacteria,1N6NN@1224|Proteobacteria,1SCRA@1236|Gammaproteobacteria,1WYYY@135613|Chromatiales 135613|Chromatiales P Protein of unknown function (DUF2892) - - - - - - - - - - - - DUF2892 k141_1191_4 391598.FBBAL38_02090 6.69e-10 59.7 COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1HX2H@117743|Flavobacteriia 976|Bacteroidetes V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran k141_34482_1 452637.Oter_4610 0.000426 48.1 COG3693@1|root,COG3693@2|Bacteria,46Z7R@74201|Verrucomicrobia 2|Bacteria G SMART Immunoglobulin C2 type - - 3.2.1.8 ko:K01181 - - - - ko00000,ko01000 - - - CBM_4_9,Glyco_hydro_10 k141_3570_1 1294265.JCM21738_4676 1.05e-90 272.0 COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,4HA3G@91061|Bacilli,1ZAVY@1386|Bacillus 91061|Bacilli T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,PAS_4,PAS_9 k141_35670_1 1121938.AUDY01000009_gene2292 1.18e-122 360.0 COG2706@1|root,COG2706@2|Bacteria,1TQ3J@1239|Firmicutes,4HBHB@91061|Bacilli,3NEG0@45667|Halobacillus 91061|Bacilli G Lactonase, 7-bladed beta-propeller pgl GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016787,GO:0016788,GO:0017057,GO:0044424,GO:0044444,GO:0044464,GO:0052689 3.1.1.31 ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R02035 RC00537 ko00000,ko00001,ko00002,ko01000 - - - Lactonase k141_4758_1 1116375.VEJY3_12645 0.0 1019.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XSRH@135623|Vibrionales 135623|Vibrionales T signal transduction protein containing a membrane domain, an EAL and a GGDEF domain VV2690 - 3.1.4.52 ko:K20965 ko05111,map05111 - - - ko00000,ko00001,ko01000 - - - EAL,GGDEF,PAS_4,PAS_8,PAS_9 k141_4758_2 1116375.VEJY3_12640 1.11e-95 280.0 COG3154@1|root,COG3154@2|Bacteria,1MZNC@1224|Proteobacteria,1S9BQ@1236|Gammaproteobacteria,1XUWR@135623|Vibrionales 135623|Vibrionales I lipid carrier protein - - - - - - - - - - - - SCP2 k141_4758_3 1116375.VEJY3_12635 2.45e-76 229.0 COG3153@1|root,COG3153@2|Bacteria,1RA42@1224|Proteobacteria,1S2G0@1236|Gammaproteobacteria,1XWYS@135623|Vibrionales 135623|Vibrionales S Acetyltransferase yhbS - - ko:K03824 - - - - ko00000,ko01000 - - - Acetyltransf_1,Acetyltransf_7,Acetyltransf_9 k141_9514_1 1209072.ALBT01000028_gene1224 2.92e-67 216.0 COG2961@1|root,COG2961@2|Bacteria,1MWGA@1224|Proteobacteria,1RNI1@1236|Gammaproteobacteria,1FH13@10|Cellvibrio 1236|Gammaproteobacteria S Specifically methylates the adenine in position 2030 of 23S rRNA rlmJ GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008988,GO:0009451,GO:0009987,GO:0010467,GO:0015976,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036307,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.266 ko:K07115 - - - - ko00000,ko01000,ko03009 - - - RsmJ k141_28537_2 1116375.VEJY3_12375 6.86e-232 640.0 COG2171@1|root,COG2171@2|Bacteria,1MYKK@1224|Proteobacteria,1RM8X@1236|Gammaproteobacteria,1XT0E@135623|Vibrionales 135623|Vibrionales H Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA dapD GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008666,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.117 ko:K00674 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R04365 RC00004,RC01136 ko00000,ko00001,ko00002,ko01000 - - - Hexapep_2,THDPS_M,THDPS_N k141_28537_3 223926.28807384 3.98e-180 511.0 COG0554@1|root,COG0554@2|Bacteria,1MUP7@1224|Proteobacteria,1RMAF@1236|Gammaproteobacteria,1XUKJ@135623|Vibrionales 135623|Vibrionales F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate glpK GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 - R00847 RC00002,RC00017 ko00000,ko00001,ko01000,ko04147 - - - FGGY_C,FGGY_N k141_26173_2 1279017.AQYJ01000024_gene933 2.62e-67 211.0 2E3UE@1|root,32YRS@2|Bacteria 2|Bacteria S Protein of unknown function (DUF2799) - - - - - - - - - - - - DUF2799 k141_26173_3 298386.PBPRA1917 3.19e-95 282.0 COG1896@1|root,COG1896@2|Bacteria,1MXEZ@1224|Proteobacteria,1RRQQ@1236|Gammaproteobacteria,1XUSC@135623|Vibrionales 135623|Vibrionales S hydrolases of HD superfamily - - - ko:K07023 - - - - ko00000 - - - HD_3 k141_26173_4 380703.AHA_3760 2.27e-77 232.0 COG3791@1|root,COG3791@2|Bacteria,1RHWZ@1224|Proteobacteria,1S4HQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Glutathione-dependent formaldehyde-activating - - - - - - - - - - - - GFA k141_26173_5 1042377.AFPJ01000030_gene439 2.22e-163 466.0 COG2055@1|root,COG2055@2|Bacteria,1MWQY@1224|Proteobacteria,1RSKW@1236|Gammaproteobacteria,4685W@72275|Alteromonadaceae 1236|Gammaproteobacteria C Malate/L-lactate dehydrogenase - - - - - - - - - - - - Ldh_2 k141_1200_1 1120980.JQKH01000047_gene1039 1.13e-39 142.0 COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,2VJ91@28216|Betaproteobacteria,2KQ8E@206351|Neisseriales 206351|Neisseriales I Psort location Cytoplasmic, score 8.96 gpsA - 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 - R00842,R00844 RC00029 ko00000,ko00001,ko01000 - - - NAD_Gly3P_dh_C,NAD_Gly3P_dh_N k141_3589_1 218284.CCDN010000001_gene1790 3.55e-187 535.0 COG0021@1|root,COG0021@2|Bacteria,1TPIB@1239|Firmicutes,4HADA@91061|Bacilli,1ZBQ6@1386|Bacillus 91061|Bacilli G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate tkt - 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C,Transketolase_N k141_16653_1 218284.CCDN010000001_gene767 8.27e-105 310.0 COG0761@1|root,COG0761@2|Bacteria,1UHT7@1239|Firmicutes,4H9S4@91061|Bacilli,1ZAUG@1386|Bacillus 91061|Bacilli IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis ispH - 1.17.7.4 ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05884,R08210 RC01137,RC01487 ko00000,ko00001,ko00002,ko01000 - - - LYTB k141_13094_1 1347086.CCBA010000010_gene1902 7.74e-13 66.2 COG4912@1|root,COG4912@2|Bacteria,1UP0J@1239|Firmicutes,4HDFV@91061|Bacilli,1ZBU5@1386|Bacillus 91061|Bacilli L DNA alkylation repair enzyme - - - - - - - - - - - - DNA_alkylation k141_13094_2 1403313.AXBR01000024_gene4863 1.58e-80 240.0 2DPEB@1|root,331RH@2|Bacteria,1VEQX@1239|Firmicutes,4HQ5P@91061|Bacilli,1ZIIN@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_14281_1 1279017.AQYJ01000024_gene972 8.21e-35 122.0 2C6YA@1|root,33M7P@2|Bacteria,1NJUZ@1224|Proteobacteria,1SJ0Y@1236|Gammaproteobacteria,46C67@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_14281_2 1042377.AFPJ01000014_gene1676 1.63e-92 277.0 COG1434@1|root,COG1434@2|Bacteria,1MVW8@1224|Proteobacteria,1S92A@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Conserved Protein - - - - - - - - - - - - DUF218 k141_3590_1 1382315.JPOI01000001_gene2835 2.74e-74 236.0 COG3314@1|root,COG3314@2|Bacteria,1TR35@1239|Firmicutes,4HAB6@91061|Bacilli,1WF31@129337|Geobacillus 91061|Bacilli S Nucleoside recognition - - - - - - - - - - - - Gate k141_19038_1 1453501.JELR01000002_gene1384 4.61e-134 385.0 COG0657@1|root,COG0657@2|Bacteria,1RD8A@1224|Proteobacteria,1S3TH@1236|Gammaproteobacteria,4687P@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG0657 Esterase lipase - - 3.1.1.83,3.1.1.85 ko:K14731,ko:K19561 ko00780,ko00903,ko00930,ko01100,ko01220,map00780,map00903,map00930,map01100,map01220 M00572 R03751,R06390,R06391,R06392,R06393,R09725 RC00460,RC00461,RC00713,RC00983,RC01505 ko00000,ko00001,ko00002,ko01000 - - - Abhydrolase_3 k141_13095_1 1231057.AMGD01000070_gene2000 7.49e-99 291.0 COG2323@1|root,COG2323@2|Bacteria,1UYR2@1239|Firmicutes,4HGVG@91061|Bacilli,26FP1@186818|Planococcaceae 91061|Bacilli S Protein of unknown function (DUF421) - - - - - - - - - - - - DUF421 k141_4780_1 1042377.AFPJ01000024_gene704 3.11e-39 140.0 COG2111@1|root,COG2111@2|Bacteria,1N1CK@1224|Proteobacteria,1RR3K@1236|Gammaproteobacteria,469GM@72275|Alteromonadaceae 1236|Gammaproteobacteria P Domain related to MnhB subunit of Na+/H+ antiporter - - - ko:K05566 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - DUF4040,MnhB k141_4780_2 1042377.AFPJ01000024_gene703 1.35e-40 139.0 COG1320@1|root,COG1320@2|Bacteria,1QTGI@1224|Proteobacteria,1RTH6@1236|Gammaproteobacteria,468PE@72275|Alteromonadaceae 1236|Gammaproteobacteria P Na+/H+ antiporter subunit - - - ko:K05571 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - PhaG_MnhG_YufB k141_1201_1 315730.BcerKBAB4_2907 8.3e-14 70.1 COG2267@1|root,COG2267@2|Bacteria,1V3S1@1239|Firmicutes,4HHI0@91061|Bacilli,1ZCG1@1386|Bacillus 91061|Bacilli I Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_5 k141_26174_1 935836.JAEL01000014_gene2085 1.55e-69 226.0 COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,4HAM7@91061|Bacilli,1ZBG8@1386|Bacillus 91061|Bacilli E COG0747 ABC-type dipeptide transport system, periplasmic component - - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 k141_3591_1 1121090.KB894709_gene1587 3.63e-110 324.0 COG1957@1|root,COG1957@2|Bacteria,1TSAR@1239|Firmicutes,4HDCS@91061|Bacilli,1ZD4R@1386|Bacillus 91061|Bacilli F nucleoside hydrolase - - 3.2.2.1 ko:K01239,ko:K01250 ko00230,ko00760,ko01100,map00230,map00760,map01100 - R01245,R01273,R01677,R01770,R02143 RC00033,RC00063,RC00122,RC00318,RC00485 ko00000,ko00001,ko01000 - - - IU_nuc_hydro k141_5966_2 935836.JAEL01000007_gene2916 2.69e-106 312.0 COG0454@1|root,COG0456@2|Bacteria,1U521@1239|Firmicutes,4HBEJ@91061|Bacilli,1ZCHR@1386|Bacillus 91061|Bacilli K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases ykwB - - - - - - - - - - - Acetyltransf_1 k141_17842_1 1042377.AFPJ01000053_gene1516 7.42e-63 204.0 COG2067@1|root,COG2067@2|Bacteria,1MV7W@1224|Proteobacteria,1RPTU@1236|Gammaproteobacteria,469RP@72275|Alteromonadaceae 1236|Gammaproteobacteria I Outer membrane protein transport protein (OMPP1/FadL/TodX) - - - ko:K06076 - - - - ko00000,ko02000 1.B.9 - - Toluene_X k141_19039_2 1499684.CCNP01000018_gene1240 0.000169 44.3 COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,247SF@186801|Clostridia,36DUE@31979|Clostridiaceae 186801|Clostridia L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage recA - - ko:K03553 ko03440,map03440 M00729 - - ko00000,ko00001,ko00002,ko03400 - - - RecA k141_7147_1 1042377.AFPJ01000034_gene2311 9.75e-31 118.0 COG0510@1|root,COG0510@2|Bacteria,1MVBB@1224|Proteobacteria,1SYBV@1236|Gammaproteobacteria,468RM@72275|Alteromonadaceae 1236|Gammaproteobacteria M Choline/ethanolamine kinase - - - - - - - - - - - - APH k141_7147_2 1492922.GY26_03505 3.46e-27 109.0 COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,1RMVU@1236|Gammaproteobacteria,1J87R@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Iron-containing alcohol dehydrogenase - - 1.1.1.1 ko:K00001,ko:K00100 ko00010,ko00071,ko00350,ko00625,ko00626,ko00650,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00650,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R03544,R03545,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - Fe-ADH k141_11902_1 218284.CCDN010000001_gene1940 5.16e-212 597.0 COG4187@1|root,COG4187@2|Bacteria,1TQQ7@1239|Firmicutes,4HABT@91061|Bacilli,1ZCEE@1386|Bacillus 91061|Bacilli E arginine degradation protein rocB - - - - - - - - - - - Peptidase_M20 k141_30922_3 1042377.AFPJ01000009_gene266 9.03e-143 410.0 COG2126@1|root,COG2126@2|Bacteria,1MXCS@1224|Proteobacteria,1RPCN@1236|Gammaproteobacteria,466D1@72275|Alteromonadaceae 1236|Gammaproteobacteria J Ion transport protein kch - - ko:K10716 - - - - ko00000,ko02000 1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6 - - Ion_trans k141_16654_1 1121933.AUHH01000032_gene1951 3.52e-172 494.0 COG0457@1|root,COG0457@2|Bacteria,2I3ME@201174|Actinobacteria,4DWWY@85009|Propionibacteriales 201174|Actinobacteria S Tetratricopeptide repeat - - - - - - - - - - - - - k141_22_1 218284.CCDN010000002_gene2873 1.75e-66 204.0 2E96H@1|root,333F3@2|Bacteria,1VBC5@1239|Firmicutes,4HKWQ@91061|Bacilli,1ZFY7@1386|Bacillus 91061|Bacilli S Tripartite tricarboxylate transporter TctB family - - - ko:K07794 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.80.1 - - TctB k141_22602_1 1294265.JCM21738_1940 1.61e-46 152.0 2BQPU@1|root,32JK9@2|Bacteria,1U2Q2@1239|Firmicutes,4IIMH@91061|Bacilli,1ZJXV@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF3899) - - - - - - - - - - - - DUF3899 k141_22602_2 1294265.JCM21738_1939 8.99e-68 221.0 COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,4HAMK@91061|Bacilli,1ZBB4@1386|Bacillus 91061|Bacilli E ABC transporter substrate-binding protein oppA - - ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 k141_9522_3 314275.MADE_1001970 1.17e-185 543.0 COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,1RQ4N@1236|Gammaproteobacteria,4648E@72275|Alteromonadaceae 1236|Gammaproteobacteria Q multicopper oxidases copA2 - - - - - - - - - - - CopB,Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3 k141_9522_4 1485545.JQLW01000005_gene1177 2.91e-51 177.0 COG3667@1|root,COG3667@2|Bacteria,1MXW6@1224|Proteobacteria 1224|Proteobacteria P copper resistance - - - ko:K07233 - - - - ko00000 - - - CopB k141_13096_1 314282.PCNPT3_07050 6.94e-88 302.0 COG5492@1|root,COG5492@2|Bacteria,1PZBJ@1224|Proteobacteria,1RZEW@1236|Gammaproteobacteria 1236|Gammaproteobacteria N PFAM Ig domain protein, group 2 domain protein - - - - - - - - - - - - Big_2,DUF1566 k141_24974_1 1279017.AQYJ01000022_gene2566 8.17e-123 357.0 COG0730@1|root,COG0730@2|Bacteria,1MXNM@1224|Proteobacteria,1RRH4@1236|Gammaproteobacteria,4681F@72275|Alteromonadaceae 1236|Gammaproteobacteria S Sulfite exporter TauE/SafE - - - ko:K07090,ko:K11312 - - - - ko00000 - - - TauE k141_18207_2 218284.CCDN010000001_gene1165 2.32e-233 651.0 COG2317@1|root,COG2317@2|Bacteria,1TPS6@1239|Firmicutes,4HAPE@91061|Bacilli,1ZB3X@1386|Bacillus 91061|Bacilli E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues ypwA GO:0003674,GO:0003824,GO:0004180,GO:0004181,GO:0005488,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0016787,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.17.19 ko:K01299 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M32 k141_25288_1 218284.CCDN010000001_gene1685 5.4e-174 518.0 COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,4HC3Y@91061|Bacilli,1ZCCY@1386|Bacillus 91061|Bacilli V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family yerP1 - - - - - - - - - - - ACR_tran k141_12291_1 42565.FP66_04355 5.82e-150 451.0 COG0506@1|root,COG4230@1|root,COG0506@2|Bacteria,COG4230@2|Bacteria,1MV93@1224|Proteobacteria,1RN48@1236|Gammaproteobacteria,1XH7V@135619|Oceanospirillales 135619|Oceanospirillales CE Oxidizes proline to glutamate for use as a carbon and nitrogen source putA - 1.2.1.88,1.5.5.2 ko:K13821 ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130 - R00245,R00707,R00708,R01253,R04444,R04445,R05051 RC00080,RC00083,RC00216,RC00242,RC00255 ko00000,ko00001,ko01000,ko03000 - - - Aldedh,Pro_dh,Pro_dh-DNA_bdg k141_33587_1 1279017.AQYJ01000024_gene1016 1.32e-36 131.0 COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,1RMR8@1236|Gammaproteobacteria,4652T@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1230 Co Zn Cd efflux system component - - - ko:K16264 - - - - ko00000,ko02000 2.A.4.1 - - Cation_efflux k141_33587_2 1279017.AQYJ01000024_gene1017 3.89e-57 193.0 COG3608@1|root,COG3608@2|Bacteria,1MUAA@1224|Proteobacteria,1RNQQ@1236|Gammaproteobacteria,464NX@72275|Alteromonadaceae 1236|Gammaproteobacteria S Succinylglutamate desuccinylase / Aspartoacylase family - - - ko:K06987 - - - - ko00000 - - - AstE_AspA k141_32320_1 518766.Rmar_2112 1.06e-61 205.0 COG0733@1|root,COG0733@2|Bacteria,4NGQ5@976|Bacteroidetes,1FJPU@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes P Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family - - - ko:K03308 - - - - ko00000 2.A.22.4,2.A.22.5 - - SNF k141_35924_1 1453501.JELR01000001_gene2219 2.85e-47 157.0 COG0424@1|root,COG0424@2|Bacteria,1RDA9@1224|Proteobacteria,1S3TQ@1236|Gammaproteobacteria,467IH@72275|Alteromonadaceae 1236|Gammaproteobacteria D COG0424 Nucleotide-binding protein implicated in inhibition of septum formation yceF GO:0003674,GO:0003824,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0047429 - ko:K06287 - - - - ko00000 - - - Maf k141_406_2 1294265.JCM21738_1203 0.000297 42.0 COG1366@1|root,COG1366@2|Bacteria,1TT64@1239|Firmicutes,4HCAK@91061|Bacilli,1ZDJS@1386|Bacillus 91061|Bacilli T STAS domain rsbRD - - ko:K17763 - - - - ko00000,ko03021 - - - HATPase_c,HisKA,STAS k141_24065_1 471223.GWCH70_2614 8.89e-100 296.0 COG1215@1|root,COG1215@2|Bacteria,1TPBB@1239|Firmicutes,4HBVS@91061|Bacilli,1WEVU@129337|Geobacillus 91061|Bacilli M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 k141_13442_1 1320556.AVBP01000007_gene444 5.85e-24 98.6 29CEM@1|root,2ZZD2@2|Bacteria,1R3NT@1224|Proteobacteria,2U04H@28211|Alphaproteobacteria,43RX6@69277|Phyllobacteriaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_21722_2 644801.Psest_3370 2.4e-08 58.2 COG4970@1|root,COG4970@2|Bacteria,1QDR3@1224|Proteobacteria,1T9UE@1236|Gammaproteobacteria,1Z3KK@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria NU Type II transport protein GspH - - - ko:K08084 - - - - ko00000,ko02044 3.A.15.2 - - GspH,N_methyl k141_20449_1 1121939.L861_17460 5.83e-82 249.0 COG4430@1|root,COG4430@2|Bacteria,1RJGC@1224|Proteobacteria,1S853@1236|Gammaproteobacteria,1XK0S@135619|Oceanospirillales 135619|Oceanospirillales S Bacteriocin-protection, YdeI or OmpD-Associated - - - - - - - - - - - - DUF1801,OmdA k141_20449_2 1122169.AREN01000005_gene1860 4.68e-109 333.0 COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,1RMKV@1236|Gammaproteobacteria,1JCKR@118969|Legionellales 118969|Legionellales E Amino acid permease - - - - - - - - - - - - AA_permease_2 k141_1447_1 1294265.JCM21738_1345 1.46e-118 341.0 COG0586@1|root,COG0586@2|Bacteria,1V31C@1239|Firmicutes,4HGNQ@91061|Bacilli,1ZICE@1386|Bacillus 91061|Bacilli S SNARE associated Golgi protein - - - ko:K03975 - - - - ko00000 - - - SNARE_assoc k141_21736_3 1453501.JELR01000002_gene1314 4.42e-31 111.0 COG1598@1|root,COG1598@2|Bacteria 2|Bacteria N PFAM Uncharacterised protein family UPF0150 ycfB - - - - - - - - - - - HicB_lk_antitox k141_33603_1 218284.CCDN010000008_gene4252 1.24e-144 416.0 COG0626@1|root,COG0626@2|Bacteria,1TPC7@1239|Firmicutes,4IS7E@91061|Bacilli,1ZS1S@1386|Bacillus 91061|Bacilli E methionine gamma-lyase megL - 4.4.1.11 ko:K01761 ko00270,ko00450,map00270,map00450 - R00654,R04770 RC00196,RC00348,RC01209,RC01210 ko00000,ko00001,ko01000 - - - Cys_Met_Meta_PP k141_22959_1 1140.Synpcc7942_2597 2.16e-21 89.4 COG2954@1|root,COG2954@2|Bacteria,1G5NQ@1117|Cyanobacteria,1H05R@1129|Synechococcus 1117|Cyanobacteria S protein conserved in bacteria - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - CYTH k141_34794_1 493475.GARC_4045 7.25e-217 626.0 COG4773@1|root,COG4773@2|Bacteria,1QTXJ@1224|Proteobacteria,1T2BS@1236|Gammaproteobacteria,46D93@72275|Alteromonadaceae 1236|Gammaproteobacteria P TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_34794_2 95619.PM1_0229315 6.3e-76 243.0 COG4977@1|root,COG4977@2|Bacteria,1MUDK@1224|Proteobacteria,1SMIT@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Transcriptional regulator cdhR - - ko:K17736 - - - - ko00000,ko03000 - - - DJ-1_PfpI,HTH_18 k141_34794_3 493475.GARC_4047 1.9e-153 437.0 COG3246@1|root,COG3246@2|Bacteria,1MZTP@1224|Proteobacteria,1RRUP@1236|Gammaproteobacteria,466BX@72275|Alteromonadaceae 1236|Gammaproteobacteria S Pfam:Kce cdhC - - - - - - - - - - - BKACE k141_34794_4 866895.HBHAL_4278 3.64e-53 178.0 COG1250@1|root,COG1250@2|Bacteria,1TQUV@1239|Firmicutes,4HC6S@91061|Bacilli,3ND4E@45667|Halobacillus 91061|Bacilli I Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine lcdH - 1.1.1.108 ko:K17735 - - - - ko00000,ko01000 - - - 3HCDH,3HCDH_N k141_24084_1 1347369.CCAD010000074_gene3476 5.53e-105 340.0 COG2909@1|root,COG3629@1|root,COG2909@2|Bacteria,COG3629@2|Bacteria,1UWHI@1239|Firmicutes,4HADH@91061|Bacilli,1ZE89@1386|Bacillus 91061|Bacilli KT COG2909 ATP-dependent transcriptional regulator - - - ko:K03556 - - - - ko00000,ko03000 - - - AAA_16,BTAD,TPR_12,TPR_8 k141_6393_2 1116375.VEJY3_07285 4.28e-252 691.0 COG0687@1|root,COG0687@2|Bacteria,1MUYW@1224|Proteobacteria,1RM7W@1236|Gammaproteobacteria,1XUH1@135623|Vibrionales 135623|Vibrionales P Required for the activity of the bacterial periplasmic transport system of putrescine potD - - ko:K11069 ko02010,map02010 M00299 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 - - SBP_bac_6,SBP_bac_8 k141_26656_1 1279017.AQYJ01000023_gene3247 6.89e-20 91.7 COG4223@1|root,COG4223@2|Bacteria,1N10X@1224|Proteobacteria,1RYCQ@1236|Gammaproteobacteria,46D2D@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF1631) - - - - - - - - - - - - DUF1631 k141_26656_2 1279017.AQYJ01000023_gene3247 1.1e-68 231.0 COG4223@1|root,COG4223@2|Bacteria,1N10X@1224|Proteobacteria,1RYCQ@1236|Gammaproteobacteria,46D2D@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF1631) - - - - - - - - - - - - DUF1631 k141_12323_1 223926.28807720 3.56e-83 249.0 COG2197@1|root,COG2197@2|Bacteria,1R531@1224|Proteobacteria,1S18M@1236|Gammaproteobacteria,1XVDS@135623|Vibrionales 135623|Vibrionales K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - ko:K04333 ko02026,map02026 - - - ko00000,ko00001,ko03000 - - - GerE k141_12323_2 1116375.VEJY3_13895 6.26e-168 471.0 COG1210@1|root,COG1210@2|Bacteria,1MV5F@1224|Proteobacteria,1RNDX@1236|Gammaproteobacteria,1XT3R@135623|Vibrionales 135623|Vibrionales M UTP--glucose-1-phosphate uridylyltransferase galU - 2.7.7.9 ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 M00129,M00361,M00362,M00549 R00289 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase k141_8656_1 218284.CCDN010000008_gene4203 1.32e-66 202.0 COG5584@1|root,COG5584@2|Bacteria,1VEIQ@1239|Firmicutes,4HNS2@91061|Bacilli,1ZJ31@1386|Bacillus 91061|Bacilli S small secreted protein ytzB - - - - - - - - - - - PepSY k141_8656_2 218284.CCDN010000008_gene4202 4.21e-30 113.0 COG0491@1|root,COG0491@2|Bacteria,1TRED@1239|Firmicutes,4HAP2@91061|Bacilli,1ZAYX@1386|Bacillus 91061|Bacilli S COG0491 Zn-dependent hydrolases, including glyoxylases ytnP - - - - - - - - - - - Lactamase_B k141_13478_2 1279017.AQYJ01000020_gene1248 2.62e-172 483.0 COG0639@1|root,COG0639@2|Bacteria,1MV10@1224|Proteobacteria,1RPUJ@1236|Gammaproteobacteria,4658I@72275|Alteromonadaceae 1236|Gammaproteobacteria T Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP apaH GO:0003674,GO:0003824,GO:0004551,GO:0004721,GO:0006139,GO:0006464,GO:0006470,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008138,GO:0008150,GO:0008152,GO:0008796,GO:0008803,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0015949,GO:0016311,GO:0016462,GO:0016787,GO:0016788,GO:0016791,GO:0016817,GO:0016818,GO:0019538,GO:0034641,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0140096,GO:1901360,GO:1901564 3.6.1.41 ko:K01525 ko00230,map00230 - R00125 RC00002 ko00000,ko00001,ko01000 - - iECIAI39_1322.ECIAI39_0052,iEcSMS35_1347.EcSMS35_0053,iJN746.PP_0399,iSDY_1059.SDY_0074 Metallophos k141_27587_1 223926.28809386 1.39e-83 255.0 COG1172@1|root,COG1172@2|Bacteria,1MX7D@1224|Proteobacteria,1RNTS@1236|Gammaproteobacteria,1XTC8@135623|Vibrionales 135623|Vibrionales G Belongs to the binding-protein-dependent transport system permease family rbsC - - ko:K10440 ko02010,map02010 M00212 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - BPD_transp_2 k141_27587_2 223926.28809387 0.0 947.0 COG1129@1|root,COG1129@2|Bacteria,1MU22@1224|Proteobacteria,1RMCH@1236|Gammaproteobacteria,1XTBT@135623|Vibrionales 135623|Vibrionales P Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system rbsA GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015146,GO:0015399,GO:0015405,GO:0015407,GO:0015591,GO:0015608,GO:0015611,GO:0015749,GO:0015750,GO:0015752,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034219,GO:0042623,GO:0042626,GO:0043211,GO:0043492,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702 3.6.3.17 ko:K10441 ko02010,map02010 M00212 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - ABC_tran k141_27587_3 223926.28809388 1.69e-81 243.0 COG1869@1|root,COG1869@2|Bacteria,1RI53@1224|Proteobacteria,1S60T@1236|Gammaproteobacteria,1XX9V@135623|Vibrionales 135623|Vibrionales G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose rbsD GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015146,GO:0015399,GO:0015405,GO:0015407,GO:0015591,GO:0015608,GO:0015611,GO:0015749,GO:0015750,GO:0015752,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034219,GO:0042623,GO:0042626,GO:0043211,GO:0043492,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702 5.4.99.62 ko:K06726 ko02010,map02010 - R08247 RC02247 ko00000,ko00001,ko01000 - - - RbsD_FucU k141_2733_1 1279017.AQYJ01000024_gene1098 1.33e-85 258.0 COG0237@1|root,COG0237@2|Bacteria,1RCXT@1224|Proteobacteria,1S3NR@1236|Gammaproteobacteria,466TA@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A coaE GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 ko:K00859 ko00770,ko01100,map00770,map01100 M00120 R00130 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - iECP_1309.ECP_0104 CoaE k141_7440_1 1453501.JELR01000002_gene1230 1.16e-164 464.0 COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,1RMFR@1236|Gammaproteobacteria,464GZ@72275|Alteromonadaceae 1236|Gammaproteobacteria K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes rpoH GO:0000150,GO:0000976,GO:0000984,GO:0000985,GO:0000988,GO:0000990,GO:0001017,GO:0001046,GO:0001047,GO:0001067,GO:0001121,GO:0001130,GO:0001131,GO:0001140,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006310,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009009,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031421,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140097,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2000142,GO:2001141 - ko:K03089 - - - - ko00000,ko03021 - - - Sigma70_r1_2,Sigma70_r2,Sigma70_r4 k141_7440_2 1279017.AQYJ01000027_gene1909 7.79e-146 422.0 COG2177@1|root,COG2177@2|Bacteria,1MU65@1224|Proteobacteria,1RYBV@1236|Gammaproteobacteria,464N0@72275|Alteromonadaceae 1236|Gammaproteobacteria D Part of the ABC transporter FtsEX involved in cellular division ftsX GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0009274,GO:0009276,GO:0009987,GO:0016020,GO:0016021,GO:0030312,GO:0030313,GO:0031224,GO:0031975,GO:0032153,GO:0044425,GO:0044464,GO:0051301,GO:0071944 - ko:K09811 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - FtsX k141_7440_3 1279017.AQYJ01000027_gene1908 4.35e-141 400.0 COG2884@1|root,COG2884@2|Bacteria,1MVQ4@1224|Proteobacteria,1RMZA@1236|Gammaproteobacteria,464ZE@72275|Alteromonadaceae 1236|Gammaproteobacteria D ATPase involved in cell division ftsE GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0019897,GO:0019898,GO:0030554,GO:0031234,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363 - ko:K09812 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - ABC_tran k141_7440_4 1279017.AQYJ01000027_gene1907 1.05e-183 526.0 COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,1RNIN@1236|Gammaproteobacteria,464WP@72275|Alteromonadaceae 1236|Gammaproteobacteria U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components ftsY GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019897,GO:0019898,GO:0031224,GO:0031226,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033036,GO:0033365,GO:0034613,GO:0035639,GO:0036094,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2,3.A.5.7 - - SRP54,SRP54_N k141_7440_5 1279017.AQYJ01000027_gene1906 9.35e-85 256.0 COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,1RN21@1236|Gammaproteobacteria,467AQ@72275|Alteromonadaceae 1236|Gammaproteobacteria L Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle rsmD GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052913,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.171 ko:K08316 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - Cons_hypoth95 k141_7440_7 1279017.AQYJ01000027_gene1904 1.38e-289 805.0 COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,464J7@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0405 Gamma-glutamyltransferase ggt - 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept k141_7440_8 1282876.BAOK01000001_gene2178 3.73e-30 112.0 2EFFX@1|root,3398N@2|Bacteria,1NCKU@1224|Proteobacteria,2UJ55@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_7440_9 1453501.JELR01000002_gene1223 2.14e-58 182.0 COG2076@1|root,COG2076@2|Bacteria,1MZ6P@1224|Proteobacteria,1S8TD@1236|Gammaproteobacteria,467U3@72275|Alteromonadaceae 1236|Gammaproteobacteria U Small Multidrug Resistance protein sugE - - ko:K11741 - - - - ko00000,ko02000 2.A.7.1 - - Multi_Drug_Res k141_7440_10 1279017.AQYJ01000027_gene1903 4.44e-101 323.0 COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,1RNB7@1236|Gammaproteobacteria 1236|Gammaproteobacteria S metal-dependent hydrolase with the TIM-barrel fold - - - - - - - - - - - - Amidohydro_3 k141_7440_15 1279017.AQYJ01000027_gene1897 6.06e-205 577.0 COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,1RMKQ@1236|Gammaproteobacteria,464IR@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine coaBC GO:0000166,GO:0003674,GO:0003824,GO:0004632,GO:0004633,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0010181,GO:0015936,GO:0015937,GO:0016829,GO:0016830,GO:0016831,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032553,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.1.1.36,6.3.2.5 ko:K13038 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 - - iEC042_1314.EC042_3945,iECUMN_1333.ECUMN_4154,iJN746.PP_5285,iSBO_1134.SBO_3641 DFP,Flavoprotein k141_7440_16 1279017.AQYJ01000027_gene1896 0.0 926.0 COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,1RMU8@1236|Gammaproteobacteria,46404@72275|Alteromonadaceae 1236|Gammaproteobacteria G Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II algC GO:0003674,GO:0003824,GO:0004615,GO:0005975,GO:0008150,GO:0008152,GO:0016853,GO:0016866,GO:0016868,GO:0044238,GO:0071704 5.4.2.2,5.4.2.8 ko:K01840,ko:K15778 ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00114 R00959,R01057,R01818,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV k141_33605_1 875328.JDM601_3121 7.9e-43 154.0 COG2801@1|root,COG2801@2|Bacteria,2I8Z0@201174|Actinobacteria,237X9@1762|Mycobacteriaceae 201174|Actinobacteria L Integrase core domain - - - - - - - - - - - - rve k141_24085_1 866895.HBHAL_3790 3.22e-43 148.0 COG0061@1|root,COG0061@2|Bacteria,1TRXB@1239|Firmicutes,4HCEW@91061|Bacilli,3NDDT@45667|Halobacillus 91061|Bacilli H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP nadK2 - 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 - R00104 RC00002,RC00078 ko00000,ko00001,ko01000 - - - NAD_kinase k141_22961_1 525367.HMPREF0556_11158 3.4e-11 63.5 COG1272@1|root,COG1272@2|Bacteria,1TSFK@1239|Firmicutes,4HAT2@91061|Bacilli,26IWQ@186820|Listeriaceae 91061|Bacilli S membrane protein, hemolysin III homolog yplQ - - ko:K11068 - - - - ko00000,ko02042 - - - HlyIII k141_29962_1 715451.ambt_06815 5.12e-80 260.0 COG4773@1|root,COG4773@2|Bacteria,1NXPR@1224|Proteobacteria,1RSBC@1236|Gammaproteobacteria,4657C@72275|Alteromonadaceae 1236|Gammaproteobacteria P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec k141_14567_1 218284.CCDN010000002_gene2895 5.16e-55 175.0 COG1226@1|root,32TGM@2|Bacteria,1VAIJ@1239|Firmicutes,4HM0V@91061|Bacilli,1ZHUM@1386|Bacillus 91061|Bacilli P Ion channel - - - ko:K08713 - - - - ko00000,ko02000 1.A.1.29.1 - - Ion_trans_2 k141_14567_2 218284.CCDN010000002_gene2893 7.22e-50 164.0 COG0861@1|root,COG0861@2|Bacteria,1UYA9@1239|Firmicutes,4HETB@91061|Bacilli,1ZRX5@1386|Bacillus 91061|Bacilli P Integral membrane protein TerC family yjbE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - TerC k141_9828_2 1121878.AUGL01000005_gene2714 3.81e-88 266.0 COG0702@1|root,COG0702@2|Bacteria,1MZG7@1224|Proteobacteria,1S39N@1236|Gammaproteobacteria 1236|Gammaproteobacteria GM Nucleoside-diphosphate-sugar epimerases - - - - - - - - - - - - Epimerase,NAD_binding_10 k141_9828_3 640081.Dsui_0431 8.83e-39 138.0 COG0697@1|root,COG0697@2|Bacteria,1MXJ6@1224|Proteobacteria,2VIA7@28216|Betaproteobacteria,2KWE2@206389|Rhodocyclales 206389|Rhodocyclales EG EamA-like transporter family - - - - - - - - - - - - EamA k141_34795_2 1479235.KK366039_gene2993 1.21e-115 334.0 COG0745@1|root,COG0745@2|Bacteria,1RA00@1224|Proteobacteria,1S23N@1236|Gammaproteobacteria,1XJE7@135619|Oceanospirillales 135619|Oceanospirillales K COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - - - - - - - - - - Response_reg,Trans_reg_C k141_5081_1 1116375.VEJY3_21416 2.98e-125 360.0 COG0599@1|root,COG0599@2|Bacteria,1QTZH@1224|Proteobacteria,1RPZW@1236|Gammaproteobacteria 1236|Gammaproteobacteria S decarboxylase - - 4.1.1.44 ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 - R03470 RC00938 ko00000,ko00001,ko01000 - - - CMD k141_5081_2 1116375.VEJY3_21421 1.74e-198 552.0 COG2207@1|root,COG2207@2|Bacteria,1MUEM@1224|Proteobacteria,1T1VS@1236|Gammaproteobacteria,1Y2JH@135623|Vibrionales 135623|Vibrionales K AraC-type transcriptional regulator N-terminus - - - - - - - - - - - - AraC_N,HTH_18 k141_5081_3 1116375.VEJY3_21491 2.74e-129 375.0 COG1979@1|root,COG1979@2|Bacteria,1QUBJ@1224|Proteobacteria,1RP7C@1236|Gammaproteobacteria,1XZTQ@135623|Vibrionales 135623|Vibrionales C Iron-containing alcohol dehydrogenase - - - - - - - - - - - - Fe-ADH k141_33606_1 320483.AMF_900 2.47e-38 142.0 COG0508@1|root,COG0508@2|Bacteria,1MUGY@1224|Proteobacteria,2TRXM@28211|Alphaproteobacteria,47EYZ@766|Rickettsiales 766|Rickettsiales C The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) pdhC - 2.3.1.12 ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding k141_26658_1 218284.CCDN010000005_gene3257 1.51e-76 235.0 COG1307@1|root,COG1307@2|Bacteria,1TQDI@1239|Firmicutes,4HAYQ@91061|Bacilli,1ZCK2@1386|Bacillus 91061|Bacilli S protein conserved in bacteria yitS - - - - - - - - - - - DegV k141_15804_1 218284.CCDN010000002_gene2955 1.43e-194 541.0 28IXS@1|root,2Z8VM@2|Bacteria,1TR3A@1239|Firmicutes,4HDYI@91061|Bacilli,1ZB0T@1386|Bacillus 91061|Bacilli S Nucleotidyltransferase-like ygxA - - - - - - - - - - - NTF-like k141_20474_1 218284.CCDN010000002_gene2909 2.57e-130 390.0 COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HA0V@91061|Bacilli,1ZBTK@1386|Bacillus 91061|Bacilli O Belongs to the ClpA ClpB family clpE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03697,ko:K04086 - - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,UVR k141_33607_1 1279017.AQYJ01000022_gene2759 2.01e-51 176.0 COG0582@1|root,COG0582@2|Bacteria 2|Bacteria L DNA integration intE GO:0003674,GO:0005488,GO:0005515,GO:0046982,GO:0046983 - ko:K21039 - - - - ko00000,ko01000 - - - Arm-DNA-bind_1,Phage_int_SAM_1,Phage_integrase k141_21738_1 1042377.AFPJ01000028_gene2306 1.45e-188 543.0 COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,1RMMQ@1236|Gammaproteobacteria,46544@72275|Alteromonadaceae 1236|Gammaproteobacteria L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) recG GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecG_wedge k141_27588_1 218284.CCDN010000006_gene3743 1.6e-08 57.8 COG1175@1|root,COG1175@2|Bacteria,1TPMR@1239|Firmicutes,4HA5B@91061|Bacilli,1ZRMB@1386|Bacillus 91061|Bacilli G Binding-protein-dependent transport system inner membrane component lacF3 - - ko:K02025,ko:K10241 ko02010,map02010 M00206,M00207 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.23 - - BPD_transp_1 k141_27588_2 218284.CCDN010000006_gene3744 6.6e-101 303.0 COG1653@1|root,COG1653@2|Bacteria,1U4H4@1239|Firmicutes,4HBJP@91061|Bacilli,1ZCZR@1386|Bacillus 91061|Bacilli G Bacterial extracellular solute-binding protein malE - - ko:K02027 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - SBP_bac_1,SBP_bac_8 k141_25299_2 1034347.CAHJ01000048_gene200 5.02e-18 79.3 29S0I@1|root,30D4V@2|Bacteria,1UAUQ@1239|Firmicutes,4IM7I@91061|Bacilli,1ZJEH@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_34797_1 218284.CCDN010000003_gene2989 1.12e-110 350.0 COG1197@1|root,COG1197@2|Bacteria,1TPF1@1239|Firmicutes,4H9NB@91061|Bacilli,1ZBAK@1386|Bacillus 91061|Bacilli L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd - - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF k141_5082_1 997296.PB1_15399 3.22e-44 147.0 COG2179@1|root,COG2179@2|Bacteria,1V6KM@1239|Firmicutes,4HGAV@91061|Bacilli,1ZFKN@1386|Bacillus 91061|Bacilli S hydrolase of the HAD superfamily yqeG - - ko:K07015 - - - - ko00000 - - - HAD_2,Hydrolase,Hydrolase_like,PGP_phosphatase k141_15805_1 1385510.N781_10895 1.12e-09 63.9 COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,4H9SR@91061|Bacilli,2Y9MZ@289201|Pontibacillus 91061|Bacilli S membrane yrrI GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - - - - - - - - - - AI-2E_transport k141_8661_1 218284.CCDN010000005_gene3213 3.38e-55 173.0 COG4392@1|root,COG4392@2|Bacteria,1VCJA@1239|Firmicutes,4HKU0@91061|Bacilli,1ZHSW@1386|Bacillus 91061|Bacilli S branched-chain amino acid - - - - - - - - - - - - AzlD k141_28890_1 1279017.AQYJ01000026_gene384 2.67e-82 254.0 COG3228@1|root,COG3228@2|Bacteria,1RAHF@1224|Proteobacteria,1RZQU@1236|Gammaproteobacteria,4674U@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the MtfA family mtfA GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0006508,GO:0006807,GO:0008134,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009889,GO:0010468,GO:0010556,GO:0016787,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031326,GO:0043170,GO:0043433,GO:0044092,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0048519,GO:0050789,GO:0050794,GO:0051090,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0065009,GO:0070011,GO:0071704,GO:0080090,GO:0140096,GO:1901564,GO:1903506,GO:2000112,GO:2001141 - ko:K09933 - - - - ko00000,ko01002 - - - Peptidase_M90 k141_28890_2 1042377.AFPJ01000014_gene1638 4.1e-98 291.0 COG2135@1|root,COG2135@2|Bacteria,1RCCC@1224|Proteobacteria,1S39B@1236|Gammaproteobacteria,46737@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the SOS response-associated peptidase family - - - - - - - - - - - - SRAP k141_28890_3 1038866.KB902846_gene6698 7.51e-07 54.7 COG1051@1|root,COG1051@2|Bacteria,1N0YW@1224|Proteobacteria,2UC2E@28211|Alphaproteobacteria,3JY9M@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria F Nudix hydrolase - - - - - - - - - - - - NUDIX k141_28906_1 314285.KT71_19784 3.93e-10 59.3 2BKZZ@1|root,32FGS@2|Bacteria,1N692@1224|Proteobacteria,1SE1T@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Sulfotransferase family - - - - - - - - - - - - Sulfotransfer_2 k141_32345_1 1294265.JCM21738_3822 3.25e-143 411.0 COG2909@1|root,COG2909@2|Bacteria,1UIMV@1239|Firmicutes,4HD7H@91061|Bacilli,1ZSHA@1386|Bacillus 91061|Bacilli K helix_turn_helix, Lux Regulon - - - ko:K03556 - - - - ko00000,ko03000 - - - GerE k141_20495_1 1042377.AFPJ01000037_gene3026 6.59e-109 320.0 COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,1RQ59@1236|Gammaproteobacteria,465TZ@72275|Alteromonadaceae 1236|Gammaproteobacteria E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline argF - 2.1.3.3,2.1.3.6,2.1.3.9 ko:K00611,ko:K09065,ko:K13252 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01398,R07245 RC00096 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N k141_14583_1 42565.FP66_15425 1.12e-117 347.0 COG3550@1|root,COG3550@2|Bacteria,1MVAB@1224|Proteobacteria,1RR5N@1236|Gammaproteobacteria 1236|Gammaproteobacteria S protein related to capsule biosynthesis enzymes hipA GO:0000166,GO:0000287,GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0003824,GO:0004672,GO:0004674,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0008144,GO:0008150,GO:0008152,GO:0009279,GO:0009297,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0015267,GO:0015288,GO:0015473,GO:0016020,GO:0016043,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018105,GO:0018193,GO:0018209,GO:0019219,GO:0019222,GO:0019538,GO:0019867,GO:0022607,GO:0022611,GO:0022803,GO:0022829,GO:0022857,GO:0030030,GO:0030031,GO:0030312,GO:0030313,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031975,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0035639,GO:0036094,GO:0036211,GO:0036289,GO:0042710,GO:0043086,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043565,GO:0043711,GO:0044010,GO:0044085,GO:0044092,GO:0044212,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044462,GO:0044464,GO:0044764,GO:0045892,GO:0045934,GO:0046777,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051179,GO:0051234,GO:0051252,GO:0051253,GO:0051704,GO:0055085,GO:0060255,GO:0065007,GO:0065009,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140096,GO:0140110,GO:1901265,GO:1901363,GO:1901564,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 2.7.11.1 ko:K07154 - - - - ko00000,ko01000,ko01001,ko02048 - - - Couple_hipA,HipA_C k141_13506_1 1051646.VITU9109_15958 5.36e-243 716.0 COG1470@1|root,COG1858@1|root,COG3391@1|root,COG4625@1|root,COG5276@1|root,COG1470@2|Bacteria,COG1858@2|Bacteria,COG3391@2|Bacteria,COG4625@2|Bacteria,COG5276@2|Bacteria,1PF0U@1224|Proteobacteria,1T9X1@1236|Gammaproteobacteria,1Y027@135623|Vibrionales 135623|Vibrionales C repeat protein - - - - - - - - - - - - - k141_13506_2 1517681.HW45_09885 4.88e-313 858.0 COG1012@1|root,COG1012@2|Bacteria,1MUHV@1224|Proteobacteria,1RNFN@1236|Gammaproteobacteria,1XTUN@135623|Vibrionales 135623|Vibrionales C COG1012 NAD-dependent aldehyde dehydrogenases - - 1.2.1.18,1.2.1.27 ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 M00013 R00705,R00706,R00922,R00935 RC00004,RC02723,RC02817 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_29980_1 1116375.VEJY3_05540 0.0 869.0 COG1757@1|root,COG1757@2|Bacteria,1MY5C@1224|Proteobacteria,1RP6I@1236|Gammaproteobacteria,1XSDA@135623|Vibrionales 135623|Vibrionales C COG1757 Na H antiporter - - - ko:K18218 - M00667 - - ko00000,ko00002,ko01504,ko02000 - - - Na_H_antiporter k141_33637_1 1042377.AFPJ01000034_gene2382 8.42e-21 90.9 COG1398@1|root,COG1398@2|Bacteria,1N2MA@1224|Proteobacteria,1RM88@1236|Gammaproteobacteria,465C3@72275|Alteromonadaceae 1236|Gammaproteobacteria I desaturase desC - 1.14.19.1 ko:K00507 ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212 - R02222 RC00917 ko00000,ko00001,ko01000,ko01004 - - - FA_desaturase k141_21758_1 762903.Pedsa_0822 7.66e-29 114.0 COG5285@1|root,COG5285@2|Bacteria 2|Bacteria Q dioxygenase activity - - - - - - - - - - - - PhyH k141_9873_1 1279017.AQYJ01000028_gene2131 2.57e-115 346.0 COG2936@1|root,COG2936@2|Bacteria,1QU2I@1224|Proteobacteria,1S1VW@1236|Gammaproteobacteria,469YI@72275|Alteromonadaceae 1236|Gammaproteobacteria S X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain - - - - - - - - - - - - PepX_C,Peptidase_S15 k141_31363_14 870967.VIS19158_20861 1.69e-41 137.0 COG2261@1|root,COG2261@2|Bacteria,1N72W@1224|Proteobacteria,1S8YP@1236|Gammaproteobacteria,1XYCC@135623|Vibrionales 135623|Vibrionales S Transglycosylase associated protein - - - - - - - - - - - - Transgly_assoc k141_31363_15 1280001.BAOA01000008_gene4100 3.49e-111 318.0 COG2983@1|root,COG2983@2|Bacteria,1RHMX@1224|Proteobacteria,1S5XU@1236|Gammaproteobacteria,1XWWH@135623|Vibrionales 135623|Vibrionales S Belongs to the UPF0260 family VV2402 - - ko:K09160 - - - - ko00000 - - - CxxCxxCC k141_31363_16 1116375.VEJY3_11185 0.0 879.0 COG0668@1|root,COG0668@2|Bacteria,1N596@1224|Proteobacteria,1RQZP@1236|Gammaproteobacteria,1XVNX@135623|Vibrionales 135623|Vibrionales M Small-conductance mechanosensitive channel - - - ko:K03442 - - - - ko00000,ko02000 1.A.23.2 - - MS_channel k141_31363_17 1116375.VEJY3_11180 0.0 930.0 COG1785@1|root,COG1785@2|Bacteria,1MXI2@1224|Proteobacteria,1RNG8@1236|Gammaproteobacteria,1XTK7@135623|Vibrionales 135623|Vibrionales P Belongs to the alkaline phosphatase family - - 3.1.3.1 ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 M00126 R02135,R04620 RC00017 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 - - - Alk_phosphatase k141_33841_1 1122194.AUHU01000015_gene2971 1.05e-81 265.0 COG4773@1|root,COG4773@2|Bacteria,1NXPR@1224|Proteobacteria,1RSBC@1236|Gammaproteobacteria,4657C@72275|Alteromonadaceae 1236|Gammaproteobacteria P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec k141_33841_2 95619.PM1_0224305 6.67e-44 149.0 COG0590@1|root,COG0590@2|Bacteria,1RHM4@1224|Proteobacteria,1S6HT@1236|Gammaproteobacteria 1236|Gammaproteobacteria FJ MafB19-like deaminase - - - - - - - - - - - - MafB19-deam,dCMP_cyt_deam_1 k141_33841_3 634499.EpC_04330 1.49e-69 220.0 COG3384@1|root,COG3384@2|Bacteria,1MXJZ@1224|Proteobacteria,1RR5P@1236|Gammaproteobacteria,3X5QM@551|Erwinia 1236|Gammaproteobacteria S Catalytic LigB subunit of aromatic ring-opening dioxygenase ygiD GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0046566,GO:0051213,GO:0055114 - ko:K15777 ko00965,map00965 - R08836 RC00387 ko00000,ko00001,ko01000 - - - LigB k141_19593_1 218284.CCDN010000005_gene3370 3.05e-77 240.0 COG0182@1|root,COG0182@2|Bacteria,1TPDK@1239|Firmicutes,4H9WM@91061|Bacilli,1ZCD9@1386|Bacillus 91061|Bacilli E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) mtnA GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 ko:K08963 ko00270,ko01100,map00270,map01100 M00034 R04420 RC01151 ko00000,ko00001,ko00002,ko01000 - - - IF-2B k141_25617_2 218284.CCDN010000007_gene3908 7.92e-122 360.0 COG3314@1|root,COG3314@2|Bacteria,1TR35@1239|Firmicutes,4HAB6@91061|Bacilli,1ZARZ@1386|Bacillus 91061|Bacilli S protein conserved in bacteria - - - - - - - - - - - - Gate k141_15988_2 1279017.AQYJ01000027_gene1742 7.43e-115 340.0 COG4531@1|root,COG4531@2|Bacteria,1QTTI@1224|Proteobacteria,1RMRJ@1236|Gammaproteobacteria,467GB@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG4531 ABC-type Zn2 transport system, periplasmic component surface adhesin znuA - - ko:K09815 ko02010,map02010 M00242 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15.3,3.A.1.15.5 - - ZnuA k141_37343_1 218284.CCDN010000001_gene729 1.88e-47 154.0 2C4MB@1|root,345EE@2|Bacteria,1W0SN@1239|Firmicutes,4HP0K@91061|Bacilli,1ZJ36@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3679) yqxA - - - - - - - - - - - DUF3679 k141_18502_1 1453501.JELR01000001_gene2812 6.02e-97 306.0 COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,1RNW3@1236|Gammaproteobacteria,464F1@72275|Alteromonadaceae 1236|Gammaproteobacteria L that it carries out the mismatch recognition step. This protein has a weak ATPase activity mutS GO:0000018,GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0008301,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030554,GO:0030983,GO:0031323,GO:0032136,GO:0032300,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1990391 - ko:K03555 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - iECW_1372.ECW_m2935,iWFL_1372.ECW_m2935 MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V k141_26949_1 519989.ECTPHS_12550 2.94e-90 275.0 COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,1RN8W@1236|Gammaproteobacteria,1WXNB@135613|Chromatiales 135613|Chromatiales BQ PFAM Histone deacetylase - - - - - - - - - - - - Hist_deacetyl k141_26949_2 1042377.AFPJ01000043_gene860 0.0 948.0 COG0427@1|root,COG1670@1|root,COG0427@2|Bacteria,COG1670@2|Bacteria,1MUGE@1224|Proteobacteria,1RP19@1236|Gammaproteobacteria,46429@72275|Alteromonadaceae 1236|Gammaproteobacteria C acetyl-CoA hydrolase - - - ko:K18288 ko00660,map00660 - R02407,R10600 RC00012,RC00014 ko00000,ko00001,ko01000 - - - AcetylCoA_hyd_C,AcetylCoA_hydro,Acetyltransf_1,Acetyltransf_3 k141_26949_4 1279017.AQYJ01000020_gene1344 4.82e-174 488.0 COG0414@1|root,COG0414@2|Bacteria,1MV1S@1224|Proteobacteria,1RMEG@1236|Gammaproteobacteria,46494@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate panC GO:0003674,GO:0003824,GO:0004592,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 M00119 R02473 RC00096,RC00141 ko00000,ko00001,ko00002,ko01000 - - iECH74115_1262.ECH74115_0142,iECSP_1301.ECSP_0134,iECs_1301.ECs0137,iG2583_1286.G2583_0137,iZ_1308.Z0144 Pantoate_ligase k141_26949_5 1042377.AFPJ01000043_gene857 1.25e-41 149.0 2DBDT@1|root,2Z8NY@2|Bacteria,1N7S2@1224|Proteobacteria,1RTZE@1236|Gammaproteobacteria,46D1R@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_26949_6 1279017.AQYJ01000020_gene1346 0.0 1112.0 COG1166@1|root,COG1166@2|Bacteria,1MU80@1224|Proteobacteria,1RP2J@1236|Gammaproteobacteria,46466@72275|Alteromonadaceae 1236|Gammaproteobacteria H arginine decarboxylase speA GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008792,GO:0009056,GO:0009058,GO:0009063,GO:0009064,GO:0009065,GO:0009308,GO:0009309,GO:0009445,GO:0009446,GO:0009987,GO:0016054,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0034641,GO:0042401,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044271,GO:0044281,GO:0044282,GO:0046395,GO:0071704,GO:0097164,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606 4.1.1.19 ko:K01585 ko00330,ko01100,map00330,map01100 M00133 R00566 RC00299 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_3590,iE2348C_1286.E2348C_3191,iEC55989_1330.EC55989_3231,iECABU_c1320.ECABU_c32250,iECED1_1282.ECED1_3401,iECIAI1_1343.ECIAI1_3071,iECIAI39_1322.ECIAI39_3358,iECO103_1326.ECO103_3518,iECO26_1355.ECO26_4037,iECOK1_1307.ECOK1_3327,iECP_1309.ECP_2933,iECS88_1305.ECS88_3221,iECSE_1348.ECSE_3207,iECSF_1327.ECSF_2737,iECSP_1301.ECSP_3909,iECUMN_1333.ECUMN_3290,iECW_1372.ECW_m3198,iECs_1301.ECs3814,iEKO11_1354.EKO11_0788,iEcE24377_1341.EcE24377A_3281,iEcHS_1320.EcHS_A3096,iEcolC_1368.EcolC_0773,iG2583_1286.G2583_3597,iLF82_1304.LF82_2157,iNRG857_1313.NRG857_14440,iPC815.YPO0929,iSBO_1134.SBO_3051,iSDY_1059.SDY_3134,iSSON_1240.SSON_3092,iSbBS512_1146.SbBS512_E3371,iWFL_1372.ECW_m3198,iZ_1308.Z4283 Orn_Arg_deC_N k141_26949_7 1453501.JELR01000002_gene1418 7.9e-288 786.0 COG1748@1|root,COG1748@2|Bacteria,1NIU2@1224|Proteobacteria,1RP49@1236|Gammaproteobacteria,4657W@72275|Alteromonadaceae 1236|Gammaproteobacteria E Saccharopine dehydrogenase HA62_29220 - 1.5.1.43,1.5.1.7 ko:K00290,ko:K13746 ko00300,ko00310,ko00330,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map00330,map01100,map01110,map01130,map01230 M00030,M00032 R00715,R09079,R09080 RC00053,RC00217,RC00225,RC01532 ko00000,ko00001,ko00002,ko01000 - - - Sacchrp_dh_C,Sacchrp_dh_NADP k141_7623_1 1042377.AFPJ01000014_gene1667 1.56e-93 289.0 28J16@1|root,2Z8Y7@2|Bacteria,1R657@1224|Proteobacteria,1SFYP@1236|Gammaproteobacteria,46BM2@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_7623_2 1279017.AQYJ01000024_gene980 7.21e-66 202.0 COG4517@1|root,COG4517@2|Bacteria,1MZJX@1224|Proteobacteria,1S95D@1236|Gammaproteobacteria,467KQ@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF1820) IV02_29925 - - - - - - - - - - - DUF1820 k141_21945_1 218284.CCDN010000001_gene1173 5.65e-152 464.0 COG0699@1|root,COG0699@2|Bacteria,1TR0Q@1239|Firmicutes,4HBAC@91061|Bacilli,1ZAXM@1386|Bacillus 91061|Bacilli S Dynamin family ypbR GO:0000910,GO:0003674,GO:0003824,GO:0003924,GO:0005575,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022402,GO:0022607,GO:0031224,GO:0032506,GO:0044085,GO:0044425,GO:0051301,GO:0071840,GO:0090529 - - - - - - - - - - Dynamin_N k141_36110_1 1279017.AQYJ01000028_gene2500 1.7e-07 51.6 COG0204@1|root,COG0204@2|Bacteria,1RJMS@1224|Proteobacteria,1S71V@1236|Gammaproteobacteria,467SS@72275|Alteromonadaceae 1236|Gammaproteobacteria I Phosphate acyltransferases - - - - - - - - - - - - Acyltransferase k141_36110_2 1121374.KB891575_gene1606 4.41e-23 92.4 COG1764@1|root,COG1764@2|Bacteria,1RJIP@1224|Proteobacteria,1S6QM@1236|Gammaproteobacteria 1236|Gammaproteobacteria O redox protein regulator of disulfide bond formation - - - - - - - - - - - - OsmC k141_37344_1 1305836.AXVE01000001_gene2814 6.55e-44 157.0 COG4963@1|root,COG4963@2|Bacteria,1UF2S@1239|Firmicutes,4HDR8@91061|Bacilli,26GA6@186818|Planococcaceae 91061|Bacilli D AAA domain - - - ko:K02282 - - - - ko00000,ko02035,ko02044 - - - AAA_31,Response_reg k141_6538_1 1116375.VEJY3_19211 4.03e-239 667.0 COG3290@1|root,COG3290@2|Bacteria,1MXQ5@1224|Proteobacteria,1RNRF@1236|Gammaproteobacteria,1XW6Z@135623|Vibrionales 135623|Vibrionales T Single cache domain 3 - - 2.7.13.3 ko:K07700 ko02020,map02020 M00486 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c_5,SPOB_a,sCache_3_2 k141_6538_2 1116375.VEJY3_19216 2.25e-144 409.0 COG4565@1|root,COG4565@2|Bacteria,1P6VJ@1224|Proteobacteria,1RPI7@1236|Gammaproteobacteria,1XX3D@135623|Vibrionales 135623|Vibrionales K cheY-homologous receiver domain - - - ko:K07702 ko02020,map02020 M00486 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg k141_6538_3 1116375.VEJY3_19221 3.82e-108 311.0 COG2606@1|root,COG2606@2|Bacteria,1N10Y@1224|Proteobacteria,1SAQE@1236|Gammaproteobacteria,1XWYK@135623|Vibrionales 135623|Vibrionales S Aminoacyl-tRNA editing domain - - - ko:K19055 - - - - ko00000,ko01000,ko03016 - - - tRNA_edit k141_6538_4 1116375.VEJY3_19226 0.0 883.0 COG0069@1|root,COG0069@2|Bacteria,1MU7B@1224|Proteobacteria,1RP1C@1236|Gammaproteobacteria,1XSHA@135623|Vibrionales 135623|Vibrionales E Belongs to the glutamate synthase family - - - - - - - - - - - - Glu_synthase,zf-CDGSH k141_6538_6 1219076.N646_4165 7.85e-99 287.0 COG5642@1|root,COG5642@2|Bacteria,1RJWF@1224|Proteobacteria,1S6CI@1236|Gammaproteobacteria,1XXH2@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF2384) - - - - - - - - - - - - DUF2384 k141_6538_7 223926.28809005 4.29e-107 308.0 COG5654@1|root,COG5654@2|Bacteria,1N6P3@1224|Proteobacteria,1S7EU@1236|Gammaproteobacteria,1XX6W@135623|Vibrionales 135623|Vibrionales S RES - - - - - - - - - - - - RES k141_1665_1 1042377.AFPJ01000052_gene1563 4.1e-40 145.0 COG2204@1|root,COG2208@1|root,COG2204@2|Bacteria,COG2208@2|Bacteria,1QU7V@1224|Proteobacteria,1T1QA@1236|Gammaproteobacteria,46693@72275|Alteromonadaceae 1236|Gammaproteobacteria KT COG0784 FOG CheY-like receiver - - 3.1.3.3 ko:K07315 - - - - ko00000,ko01000,ko03021 - - - Response_reg,SpoIIE k141_1665_2 1453501.JELR01000002_gene305 2.39e-24 99.0 COG2853@1|root,COG2853@2|Bacteria,1MVX0@1224|Proteobacteria,1RNPS@1236|Gammaproteobacteria,466E2@72275|Alteromonadaceae 1236|Gammaproteobacteria M Surface lipoprotein vacJ - - ko:K04754 - - - - ko00000 - - - MlaA k141_20717_1 1279017.AQYJ01000025_gene701 5.3e-71 238.0 COG2887@1|root,COG2887@2|Bacteria,1QVX1@1224|Proteobacteria,1RP9I@1236|Gammaproteobacteria,465DQ@72275|Alteromonadaceae 1236|Gammaproteobacteria L PD-(D/E)XK nuclease superfamily lidB - - - - - - - - - - - PDDEXK_1 k141_24291_1 1123290.AUDQ01000022_gene739 1.43e-59 204.0 COG0697@1|root,COG0697@2|Bacteria,1TP7K@1239|Firmicutes,4HAH1@91061|Bacilli,26E1D@186818|Planococcaceae 91061|Bacilli EG Bacillus/Clostridium GerA spore germination protein gerKA - - ko:K06295 - - - - ko00000 - - - GerA k141_33871_1 218284.CCDN010000001_gene1588 9.21e-151 432.0 COG4948@1|root,COG4948@2|Bacteria,1TQMS@1239|Firmicutes,4HCY5@91061|Bacilli,1ZC5Y@1386|Bacillus 91061|Bacilli M Belongs to the mandelate racemase muconate lactonizing enzyme family ykfB - 5.1.1.20 ko:K19802 - - R10938 RC03309 ko00000,ko01000 - - - MR_MLE_C,MR_MLE_N k141_13810_1 218284.CCDN010000001_gene757 3.78e-119 342.0 COG0517@1|root,COG0517@2|Bacteria,1TRZD@1239|Firmicutes,4HC4C@91061|Bacilli,1ZB0P@1386|Bacillus 91061|Bacilli K CBS domain ccpN GO:0006355,GO:0007154,GO:0007584,GO:0008150,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0042221,GO:0045013,GO:0045892,GO:0045934,GO:0045990,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0061984,GO:0061985,GO:0065007,GO:0070887,GO:0071496,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - - - - - - - - - - CBS,HTH_11 k141_18503_1 566466.NOR53_3118 1.06e-18 90.1 COG0709@1|root,COG1252@1|root,COG0709@2|Bacteria,COG1252@2|Bacteria,1MWFG@1224|Proteobacteria,1RQ5Q@1236|Gammaproteobacteria,1J7Q0@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria CE Belongs to the selenophosphate synthase 1 family. Class I subfamily - - 2.7.9.3 ko:K01008 ko00450,ko01100,map00450,map01100 - R03595 RC00002,RC02878 ko00000,ko00001,ko01000,ko03016 - - - AIRS,AIRS_C,Pyr_redox_2 k141_14754_2 797209.ZOD2009_13606 3.06e-22 92.4 COG4818@1|root,arCOG04344@2157|Archaea,2Y00G@28890|Euryarchaeota,23XT0@183963|Halobacteria 183963|Halobacteria S membrane - - - - - - - - - - - - DUF4870 k141_27737_2 1116375.VEJY3_04575 8.17e-285 780.0 COG2718@1|root,COG2718@2|Bacteria,1MWQM@1224|Proteobacteria,1RQWC@1236|Gammaproteobacteria,1XSXD@135623|Vibrionales 135623|Vibrionales S Belongs to the UPF0229 family yeaH - - ko:K09786 - - - - ko00000 - - - DUF444 k141_27737_3 1116375.VEJY3_04570 0.0 1033.0 COG2719@1|root,COG2719@2|Bacteria,1MW6U@1224|Proteobacteria,1RPU2@1236|Gammaproteobacteria,1XTA0@135623|Vibrionales 135623|Vibrionales S SpoVR family ycgB - - - - - - - - - - - SpoVR k141_27737_4 223926.28805971 6.15e-81 245.0 COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,1RMAE@1236|Gammaproteobacteria,1XTK4@135623|Vibrionales 135623|Vibrionales M Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria kdsB GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008690,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0046401,GO:0070567,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.7.38 ko:K00979 ko00540,ko01100,map00540,map01100 M00063 R03351,R11396 RC00152,RC00910 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CTP_transf_3 k141_19625_1 223926.28806520 1.43e-234 648.0 COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,1RNPX@1236|Gammaproteobacteria,1XT3F@135623|Vibrionales 135623|Vibrionales P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system potA GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015203,GO:0015399,GO:0015405,GO:0015417,GO:0015695,GO:0015696,GO:0015846,GO:0015847,GO:0015848,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:1902047 3.6.3.31 ko:K11072 ko02010,map02010 M00299 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.11.1 - - ABC_tran,TOBE_2 k141_11363_2 1116375.VEJY3_00845 1.57e-147 416.0 COG0461@1|root,COG0461@2|Bacteria,1MW6F@1224|Proteobacteria,1RQYG@1236|Gammaproteobacteria,1XT4F@135623|Vibrionales 135623|Vibrionales F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) pyrE GO:0003674,GO:0003824,GO:0004588,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.10 ko:K00762 ko00240,ko01100,map00240,map01100 M00051 R01870 RC00611 ko00000,ko00001,ko00002,ko01000 - - - Pribosyltran k141_11363_3 674977.VMC_14290 1.32e-161 453.0 COG0689@1|root,COG0689@2|Bacteria,1MVFZ@1224|Proteobacteria,1RNTB@1236|Gammaproteobacteria,1XU74@135623|Vibrionales 135623|Vibrionales J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates rph GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006401,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019439,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 ko:K00989 - - - - ko00000,ko01000,ko03016 - - - RNase_PH,RNase_PH_C k141_11363_4 1116375.VEJY3_00835 2.28e-130 374.0 COG1561@1|root,COG1561@2|Bacteria,1MWRA@1224|Proteobacteria,1RMAB@1236|Gammaproteobacteria,1XSZ4@135623|Vibrionales 135623|Vibrionales S stress-induced protein - - - - - - - - - - - - DUF1732,YicC_N k141_7625_2 218284.CCDN010000001_gene1648 9.67e-91 282.0 COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4H9ZK@91061|Bacilli,1ZCFC@1386|Bacillus 91061|Bacilli S ABC transporter - - - - - - - - - - - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn k141_17170_1 1122194.AUHU01000005_gene870 6.24e-110 338.0 COG1629@1|root,COG4771@2|Bacteria,1R5B9@1224|Proteobacteria,1S13U@1236|Gammaproteobacteria,469BN@72275|Alteromonadaceae 1236|Gammaproteobacteria P Carboxypeptidase regulatory-like domain - - - - - - - - - - - - CarboxypepD_reg,Plug,TonB_dep_Rec k141_36111_1 218284.CCDN010000001_gene632 4.54e-73 234.0 COG1530@1|root,COG1530@2|Bacteria,1TQS4@1239|Firmicutes,4HC3Q@91061|Bacilli,1ZCCF@1386|Bacillus 91061|Bacilli J ribonuclease, Rne Rng family rng - - ko:K08301 - - - - ko00000,ko01000,ko03009,ko03019 - - - RNase_E_G,S1 k141_36111_2 218284.CCDN010000001_gene631 5.41e-10 58.5 COG1994@1|root,COG1994@2|Bacteria,1V72P@1239|Firmicutes,4HJFP@91061|Bacilli,1ZQIE@1386|Bacillus 91061|Bacilli S Peptidase family M50 spoIVFB - - ko:K06402 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M50,Peptidase_M50B k141_13811_1 1294265.JCM21738_2004 4.98e-133 384.0 COG0628@1|root,COG0628@2|Bacteria,1TSI9@1239|Firmicutes,4HB3Q@91061|Bacilli,1ZD70@1386|Bacillus 91061|Bacilli S AI-2E family transporter - - - - - - - - - - - - AI-2E_transport k141_30147_1 218284.CCDN010000001_gene1295 2.8e-127 363.0 28IW6@1|root,2Z8UG@2|Bacteria,1TSGG@1239|Firmicutes,4HCTI@91061|Bacilli,1ZBNE@1386|Bacillus 91061|Bacilli S YvbH-like oligomerisation region yvbH - - - - - - - - - - - YvbH_ext,bPH_1 k141_11364_1 1056512.D515_03890 2.37e-69 226.0 COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,1RMWS@1236|Gammaproteobacteria,1XTI6@135623|Vibrionales 135623|Vibrionales F bifunctional purine biosynthesis protein purh purH GO:0003674,GO:0003824,GO:0004643,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 - - - AICARFT_IMPCHas,MGS k141_19626_1 203122.Sde_3447 3e-67 229.0 COG4677@1|root,COG4677@2|Bacteria,1QX0R@1224|Proteobacteria,1T32P@1236|Gammaproteobacteria,46D3U@72275|Alteromonadaceae 1236|Gammaproteobacteria G Pectinesterase - - - - - - - - - - - - Pectinesterase k141_21948_2 1385514.N782_09860 4.78e-12 65.1 COG1597@1|root,COG1597@2|Bacteria,1TQAU@1239|Firmicutes,4H9WD@91061|Bacilli,2Y967@289201|Pontibacillus 91061|Bacilli G to YegS from E. coli - - - - - - - - - - - - DAGK_cat k141_33873_1 42565.FP66_12395 9.25e-111 322.0 2BVTQ@1|root,2Z7J9@2|Bacteria,1P01Z@1224|Proteobacteria,1RNNB@1236|Gammaproteobacteria,1XIR7@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF2797) - - - - - - - - - - - - DUF2797 k141_33873_2 42565.FP66_12400 1.52e-30 108.0 COG3139@1|root,COG3139@2|Bacteria,1N7ZT@1224|Proteobacteria,1SC7K@1236|Gammaproteobacteria,1XMEW@135619|Oceanospirillales 135619|Oceanospirillales S protein conserved in bacteria - - - ko:K09916 - - - - ko00000 - - - DUF1315 k141_6539_1 1042377.AFPJ01000024_gene738 4.73e-117 350.0 COG0635@1|root,COG0635@2|Bacteria,1MV1I@1224|Proteobacteria,1RN1Y@1236|Gammaproteobacteria,46465@72275|Alteromonadaceae 1236|Gammaproteobacteria H Belongs to the anaerobic coproporphyrinogen-III oxidase family hemN - 1.3.98.3 ko:K02495 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R06895 RC00884 ko00000,ko00001,ko00002,ko01000 - - - HemN_C,Radical_SAM k141_13812_1 42565.FP66_12240 2.27e-36 127.0 COG3313@1|root,COG3313@2|Bacteria,1N711@1224|Proteobacteria,1S5BC@1236|Gammaproteobacteria,1XR0N@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF1289) - - - ko:K06938 - - - - ko00000 - - - DUF1289 k141_32534_1 439235.Dalk_1399 1.13e-67 218.0 COG4221@1|root,COG4221@2|Bacteria,1R08W@1224|Proteobacteria,43CRM@68525|delta/epsilon subdivisions 1224|Proteobacteria S Polysaccharide biosynthesis protein - - - - - - - - - - - - adh_short k141_12628_3 1279017.AQYJ01000020_gene1309 3.52e-146 429.0 COG5339@1|root,COG5339@2|Bacteria,1QPEJ@1224|Proteobacteria,1SJ4D@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Bacterial protein of unknown function (DUF945) - - - - - - - - - - - - DUF945 k141_14755_1 218284.CCDN010000002_gene2870 1.4e-189 538.0 COG3290@1|root,COG3290@2|Bacteria,1TQJR@1239|Firmicutes,4H9Q0@91061|Bacilli,1ZBHV@1386|Bacillus 91061|Bacilli T Signal transduction histidine kinase regulating citrate malate metabolism citS - 2.7.13.3 ko:K11637 ko02020,map02020 M00487 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,PAS,PAS_8,PAS_9,SPOB_a,sCache_3_2 k141_26952_2 471854.Dfer_3936 3.94e-79 241.0 COG0494@1|root,COG0494@2|Bacteria,4NHER@976|Bacteroidetes,47MQ4@768503|Cytophagia 976|Bacteroidetes L NUDIX domain nudK - - - - - - - - - - - NUDIX k141_18504_1 1232410.KI421413_gene595 1.51e-54 184.0 COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,42KZG@68525|delta/epsilon subdivisions,2WIQ5@28221|Deltaproteobacteria,43SCX@69541|Desulfuromonadales 28221|Deltaproteobacteria F Carbamoyl-phosphate synthase small chain, CPSase domain carA - 6.3.5.5 ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_sm_chain,GATase k141_18504_2 1385517.N800_05615 1.04e-08 62.4 COG0204@1|root,COG0204@2|Bacteria,1N2DG@1224|Proteobacteria,1S7SZ@1236|Gammaproteobacteria,1X5QD@135614|Xanthomonadales 135614|Xanthomonadales I acetyltransferase plsC1 - 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase k141_21949_1 218284.CCDN010000001_gene1001 1.3e-94 285.0 COG2195@1|root,COG2195@2|Bacteria,1TP3A@1239|Firmicutes,4HA04@91061|Bacilli,1ZBSY@1386|Bacillus 91061|Bacilli E COG2195 Di- and tripeptidases yqjE - 3.4.11.14,3.4.11.4 ko:K01258,ko:K01263 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20,Peptidase_M28 k141_20718_2 218284.CCDN010000001_gene990 6.47e-166 483.0 COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,1TQAD@1239|Firmicutes,4H9QB@91061|Bacilli,1ZCKD@1386|Bacillus 91061|Bacilli I COG1884 Methylmalonyl-CoA mutase, N-terminal domain subunit mutB - 5.4.99.2 ko:K01847 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00373,M00376,M00741 R00833 RC00395 ko00000,ko00001,ko00002,ko01000 - - - B12-binding,MM_CoA_mutase k141_19627_1 218284.CCDN010000002_gene2577 2.33e-56 188.0 COG4191@1|root,COG4191@2|Bacteria,1UZ9W@1239|Firmicutes,4HDK2@91061|Bacilli,1ZD85@1386|Bacillus 91061|Bacilli T Histidine kinase - - 2.7.13.3 ko:K07697 ko02020,map02020 M00485 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - 5TM-5TMR_LYT,HATPase_c,HisKA k141_8957_1 218284.CCDN010000001_gene18 2.92e-79 236.0 2BIN4@1|root,32CV6@2|Bacteria,1VC14@1239|Firmicutes,4HJYF@91061|Bacilli,1ZGYX@1386|Bacillus 91061|Bacilli S YlqD protein - - - - - - - - - - - - YlqD k141_8957_2 218284.CCDN010000001_gene17 1.75e-10 58.5 COG0806@1|root,COG0806@2|Bacteria,1V6HD@1239|Firmicutes,4HH3H@91061|Bacilli,1ZFP2@1386|Bacillus 91061|Bacilli J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes rimM - - ko:K02860 - - - - ko00000,ko03009 - - - PRC,RimM k141_35100_2 218284.CCDN010000001_gene48 4.17e-40 133.0 COG1758@1|root,COG1758@2|Bacteria,1VK74@1239|Firmicutes,4HNHS@91061|Bacilli,1ZIVD@1386|Bacillus 91061|Bacilli K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits rpoZ - 2.7.7.6 ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb6 k141_37366_1 218284.CCDN010000005_gene3227 4.45e-16 77.0 COG0477@1|root,COG2814@2|Bacteria,1UXYG@1239|Firmicutes,4HBZB@91061|Bacilli,1ZQ79@1386|Bacillus 91061|Bacilli EGP COG0477 Permeases of the major facilitator superfamily ynfM3 - - - - - - - - - - - MFS_1,Sugar_tr k141_37366_2 218284.CCDN010000005_gene3228 8.86e-79 259.0 COG3857@1|root,COG3857@2|Bacteria,1TQJW@1239|Firmicutes,4HAY6@91061|Bacilli,1ZC70@1386|Bacillus 91061|Bacilli L ATP-dependent helicase deoxyribonuclease subunit B rexB GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0004527,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.6.4.12 ko:K16899 - - - - ko00000,ko01000,ko03400 - - - Exonuc_V_gamma,PDDEXK_1,UvrD_C k141_11402_1 1246484.D479_00135 3.01e-80 239.0 COG3773@1|root,COG3773@2|Bacteria,1V3QK@1239|Firmicutes,4HH00@91061|Bacilli,3NEWQ@45667|Halobacillus 91061|Bacilli M Cell Wall Hydrolase cwlJ - 3.5.1.28 ko:K01449 - - R04112 RC00064,RC00141 ko00000,ko01000 - - - Hydrolase_2 k141_14774_1 218284.CCDN010000001_gene1666 4.14e-55 178.0 COG2323@1|root,COG2323@2|Bacteria,1TX6U@1239|Firmicutes,4HEB2@91061|Bacilli,1ZQ03@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF421) - - - - - - - - - - - - DUF421 k141_14774_2 406124.ACPC01000046_gene2371 6.22e-28 105.0 2CHF3@1|root,32VSH@2|Bacteria,1VE4P@1239|Firmicutes,4HKKU@91061|Bacilli,1ZH4X@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_2898_2 42565.FP66_13865 1.91e-93 283.0 COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,1RMP9@1236|Gammaproteobacteria,1XHFB@135619|Oceanospirillales 135619|Oceanospirillales M Lipoprotein releasing system, transmembrane protein lolC - - ko:K09808 ko02010,map02010 M00255 - - ko00000,ko00001,ko00002,ko02000 3.A.1.125 - - FtsX,MacB_PCD k141_20737_1 218284.CCDN010000008_gene4244 5.69e-05 44.3 COG0517@1|root,COG0517@2|Bacteria,1V0XU@1239|Firmicutes,4HD12@91061|Bacilli,1ZBNZ@1386|Bacillus 91061|Bacilli S Acetoin utilization protein AcuB acuB - - ko:K04767 - - - - ko00000 - - - ACT,CBS k141_20737_2 218284.CCDN010000008_gene4245 7.22e-147 414.0 COG0454@1|root,COG0454@2|Bacteria,1TSEY@1239|Firmicutes,4HA1V@91061|Bacilli,1ZANI@1386|Bacillus 91061|Bacilli K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue acuA GO:0001101,GO:0003674,GO:0003824,GO:0006066,GO:0006355,GO:0006950,GO:0007154,GO:0007584,GO:0008150,GO:0008152,GO:0009056,GO:0009267,GO:0009605,GO:0009847,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010033,GO:0010034,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016407,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019152,GO:0019219,GO:0019222,GO:0019751,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0032502,GO:0033554,GO:0034077,GO:0034078,GO:0034311,GO:0034313,GO:0042149,GO:0042180,GO:0042182,GO:0042221,GO:0042594,GO:0042844,GO:0042846,GO:0043894,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0045013,GO:0045014,GO:0045149,GO:0045150,GO:0045892,GO:0045934,GO:0045990,GO:0046015,GO:0046164,GO:0046174,GO:0046677,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0055114,GO:0060255,GO:0061984,GO:0061985,GO:0061986,GO:0065007,GO:0070887,GO:0071229,GO:0071236,GO:0071310,GO:0071311,GO:0071496,GO:0071704,GO:0080090,GO:1901575,GO:1901615,GO:1901616,GO:1901700,GO:1901701,GO:1902652,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K04766 - - - - ko00000,ko01000 - - - Acetyltransf_1 k141_13841_1 1123256.KB907928_gene2063 5.52e-17 83.2 COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,1RPI8@1236|Gammaproteobacteria,1X3EP@135614|Xanthomonadales 135614|Xanthomonadales L Tyrosine recombinase xerD xerD - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase k141_10233_1 218284.CCDN010000001_gene148 1.33e-108 320.0 COG2070@1|root,COG2070@2|Bacteria,1TPC3@1239|Firmicutes,4H9T0@91061|Bacilli,1ZBRG@1386|Bacillus 91061|Bacilli S COG2070 Dioxygenases related to 2-nitropropane dioxygenase - - 1.3.1.9 ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00083 R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765 RC00052,RC00076 ko00000,ko00001,ko00002,ko01000,ko01004 - - - NMO k141_18515_1 1295642.H839_06929 2.81e-214 602.0 COG0160@1|root,COG0160@2|Bacteria,1VS6F@1239|Firmicutes,4H9M7@91061|Bacilli,1WES9@129337|Geobacillus 91061|Bacilli E Aminotransferase class-III gabT - 2.6.1.19 ko:K00823 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 M00027 R00908,R01648 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 k141_21969_1 414684.RC1_1776 7.85e-61 199.0 COG0334@1|root,COG0334@2|Bacteria,1MUXS@1224|Proteobacteria,2VGKD@28211|Alphaproteobacteria,2JP8T@204441|Rhodospirillales 204441|Rhodospirillales E Glutamate/Leucine/Phenylalanine/Valine dehydrogenase - - 1.4.1.9 ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 - R01088,R01434,R02196 RC00006,RC00036 ko00000,ko00001,ko01000 - - - ELFV_dehydrog,ELFV_dehydrog_N k141_8982_1 1219076.N646_0186 3.59e-144 411.0 COG0040@1|root,COG0040@2|Bacteria,1MUCY@1224|Proteobacteria,1RNAX@1236|Gammaproteobacteria,1XTJ4@135623|Vibrionales 135623|Vibrionales F Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity hisG GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 ko:K00765 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002,ko01000 - - - HisG,HisG_C k141_7642_1 1078085.HMPREF1210_00657 6.39e-51 182.0 COG1404@1|root,COG2755@1|root,COG1404@2|Bacteria,COG2755@2|Bacteria,1TPH1@1239|Firmicutes,4HBQH@91061|Bacilli 91061|Bacilli O Belongs to the peptidase S8 family prtS - 3.4.21.110,3.4.21.96 ko:K01361,ko:K08652 - - - - ko00000,ko01000,ko01002,ko03110 - - - FIVAR,Gram_pos_anchor,Inhibitor_I9,PA,Peptidase_S8,SLH,YSIRK_signal,fn3_5 k141_11403_1 1218173.BALCAV_0214630 1.07e-89 279.0 COG2972@1|root,COG2972@2|Bacteria,1TSF9@1239|Firmicutes,4HAIW@91061|Bacilli,1ZC6Y@1386|Bacillus 91061|Bacilli T Histidine kinase - - - - - - - - - - - - HAMP,HATPase_c,His_kinase k141_17354_1 1294265.JCM21738_1478 1.56e-123 373.0 COG1048@1|root,COG1048@2|Bacteria,1VTMM@1239|Firmicutes,4HB5N@91061|Bacilli,1ZART@1386|Bacillus 91061|Bacilli C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate citB GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0043937,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0050789,GO:0050793,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0065007,GO:0071704,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS06730 Aconitase,Aconitase_C k141_10407_1 234267.Acid_5295 4.38e-36 124.0 COG1977@1|root,COG1977@2|Bacteria,3Y5J3@57723|Acidobacteria 57723|Acidobacteria H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin - - - - - - - - - - - - - k141_10407_2 1469245.JFBG01000001_gene530 1.81e-31 120.0 COG0500@1|root,COG2226@2|Bacteria 2|Bacteria Q methyltransferase - - - - - - - - - - - - Methyltransf_23,Methyltransf_25,Pyr_redox_2 k141_5692_1 1499680.CCFE01000021_gene2124 2.65e-44 157.0 COG3920@1|root,COG3920@2|Bacteria,1TRK3@1239|Firmicutes,4HAMI@91061|Bacilli,1ZC5C@1386|Bacillus 91061|Bacilli T Histidine kinase pdtaS - 2.7.13.3 ko:K00936 - M00839 - - ko00000,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HATPase_c_2,H_kinase_N,HisKA_2 k141_5692_2 665959.HMPREF1013_03578 6.07e-88 263.0 COG3707@1|root,COG3707@2|Bacteria,1U6TA@1239|Firmicutes,4HI2C@91061|Bacilli,1ZF0Q@1386|Bacillus 91061|Bacilli T ANTAR - - - ko:K22010 - M00839 - - ko00000,ko00002,ko02022 - - - ANTAR,Response_reg k141_5692_3 1196031.ALEG01000065_gene77 1.55e-58 192.0 COG3192@1|root,COG3192@2|Bacteria,1TNZF@1239|Firmicutes,4HAQ8@91061|Bacilli,1ZCSJ@1386|Bacillus 91061|Bacilli E Ethanolamine utilisation protein, EutH eutH GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K04023 - - - - ko00000 - - iYO844.BSU39450 EutH k141_24631_1 42565.FP66_09490 1.8e-100 305.0 COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,1RP5S@1236|Gammaproteobacteria,1XIIJ@135619|Oceanospirillales 135619|Oceanospirillales S Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state - - - - - - - - - - - - Peptidase_M48,TPR_16,TPR_19 k141_35379_1 674977.VMC_37350 1.19e-126 366.0 COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,1RR68@1236|Gammaproteobacteria,1XSSR@135623|Vibrionales 135623|Vibrionales H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate moaA GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.22 ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09394 RC03420 ko00000,ko00001,ko01000 - - - Fer4_12,Mob_synth_C,Radical_SAM k141_915_2 218284.CCDN010000001_gene1432 1.38e-83 247.0 COG2210@1|root,COG2210@2|Bacteria,1V3UE@1239|Firmicutes,4HH93@91061|Bacilli,1ZQ9Q@1386|Bacillus 91061|Bacilli S DsrE/DsrF-like family perX - - - - - - - - - - - DrsE_2 k141_1878_1 1294265.JCM21738_2819 4.25e-187 534.0 COG3852@1|root,COG3852@2|Bacteria,1TRH0@1239|Firmicutes,4HD4A@91061|Bacilli,1ZARI@1386|Bacillus 91061|Bacilli T COG0642 Signal transduction histidine kinase - - 2.7.13.3 ko:K02491 ko02020,map02020 M00485 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - 5TM-5TMR_LYT,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9 k141_15017_1 218284.CCDN010000005_gene3224 1.38e-101 304.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,1ZB7V@1386|Bacillus 91061|Bacilli I Belongs to the thiolase family thlA - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N k141_9275_1 666686.B1NLA3E_16335 1.05e-82 251.0 COG0500@1|root,COG2226@2|Bacteria,1V3T6@1239|Firmicutes,4HHF1@91061|Bacilli,1ZFN7@1386|Bacillus 91061|Bacilli Q Could be a S-adenosyl-L-methionine-dependent methyltransferase yrrT GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 - ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 M00609 R10404 RC00003 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_11,Methyltransf_23,Methyltransf_25 k141_32809_1 1294265.JCM21738_4033 2.33e-17 74.7 COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,4H9T1@91061|Bacilli,1ZB77@1386|Bacillus 91061|Bacilli M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan murE GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 ko:K01928 ko00300,ko00550,map00300,map00550 - R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M k141_32809_2 1294265.JCM21738_4034 1.03e-89 264.0 COG0770@1|root,COG0770@2|Bacteria,1VWQC@1239|Firmicutes,4HXPV@91061|Bacilli,1ZFWM@1386|Bacillus 91061|Bacilli M UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity - - - - - - - - - - - - - k141_25921_1 42565.FP66_07460 2.97e-15 72.0 COG1309@1|root,COG1309@2|Bacteria,1MWF7@1224|Proteobacteria,1RPZ6@1236|Gammaproteobacteria,1XJ6Q@135619|Oceanospirillales 135619|Oceanospirillales D Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions slmA - - ko:K05501 - - - - ko00000,ko03000,ko03036 - - - TetR_N k141_25921_2 42565.FP66_07455 1.07e-86 261.0 COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,1RNKK@1236|Gammaproteobacteria,1XHR1@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the acetylglutamate kinase family. ArgB subfamily argB - 2.3.1.1,2.7.2.8 ko:K00930,ko:K22478 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R00259,R02649 RC00002,RC00004,RC00043,RC00064 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase k141_4335_1 218284.CCDN010000008_gene4169 6.37e-159 457.0 COG1866@1|root,COG1866@2|Bacteria,1TPQV@1239|Firmicutes,4HAKG@91061|Bacilli,1ZCVN@1386|Bacillus 91061|Bacilli C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA pckA GO:0000166,GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0017076,GO:0019318,GO:0019319,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576 4.1.1.49 ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 M00003,M00170 R00341 RC00002,RC02741 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS09060,iYO844.BSU30560 PEPCK_ATP k141_10413_1 1280001.BAOA01000078_gene3133 3.21e-137 390.0 COG0247@1|root,COG0247@2|Bacteria,1NKKI@1224|Proteobacteria,1SM16@1236|Gammaproteobacteria,1XW54@135623|Vibrionales 135623|Vibrionales C Cysteine-rich domain - - - - - - - - - - - - CCG k141_35380_2 42565.FP66_09040 3.36e-64 204.0 COG0042@1|root,COG0042@2|Bacteria,1MUY1@1224|Proteobacteria,1RN28@1236|Gammaproteobacteria,1XI2R@135619|Oceanospirillales 135619|Oceanospirillales J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs dusA - - ko:K05539 - - - - ko00000,ko01000,ko03016 - - - Dus k141_7913_1 1408303.JNJJ01000079_gene1351 4.77e-53 178.0 2EYI3@1|root,33RRY@2|Bacteria,1VU68@1239|Firmicutes,4HT3P@91061|Bacilli,1ZF3R@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_9276_1 880073.Calab_2803 5.29e-98 299.0 COG0423@1|root,COG0423@2|Bacteria,2NNN9@2323|unclassified Bacteria 2|Bacteria J Catalyzes the attachment of glycine to tRNA(Gly) glyQS GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009345,GO:0009987,GO:0010467,GO:0016070,GO:0016594,GO:0016597,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0042165,GO:0042802,GO:0042803,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046983,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.14 ko:K01880 ko00970,map00970 M00359,M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - iSB619.SA_RS07880 HGTP_anticodon,tRNA-synt_2b k141_37519_1 1116375.VEJY3_14505 1.03e-102 313.0 COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,1RMTB@1236|Gammaproteobacteria,1XSXK@135623|Vibrionales 135623|Vibrionales O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions groL GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 - - - Cpn60_TCP1 k141_37519_2 1280001.BAOA01000011_gene4267 1.01e-113 328.0 2BN55@1|root,32GS7@2|Bacteria,1R7WY@1224|Proteobacteria,1RQ71@1236|Gammaproteobacteria,1XU9A@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_37519_3 674977.VMC_23380 1.2e-100 293.0 COG1285@1|root,COG1285@2|Bacteria,1MURJ@1224|Proteobacteria,1S78Y@1236|Gammaproteobacteria,1XX2P@135623|Vibrionales 135623|Vibrionales S MgtC family - - - ko:K07507 - - - - ko00000,ko02000 9.B.20 - - MgtC k141_37519_4 1116375.VEJY3_14490 7.72e-232 639.0 COG1509@1|root,COG1509@2|Bacteria,1MUPJ@1224|Proteobacteria,1RM84@1236|Gammaproteobacteria,1XUU0@135623|Vibrionales 135623|Vibrionales C Lysine 2,3-aminomutase yjeK - - ko:K19810 - - - - ko00000,ko01000,ko03012 - - - Fer4_12,Fer4_14,Radical_SAM k141_37519_5 1280001.BAOA01000011_gene4270 6.82e-132 374.0 COG0231@1|root,COG0231@2|Bacteria,1MW2J@1224|Proteobacteria,1RPW7@1236|Gammaproteobacteria,1XSP6@135623|Vibrionales 135623|Vibrionales J Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation efp GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02356 - - - - ko00000,ko03012 - - - EFP,EFP_N,Elong-fact-P_C k141_37519_6 675816.VIA_004165 4.37e-84 248.0 COG3080@1|root,COG3080@2|Bacteria,1RDZD@1224|Proteobacteria,1S3W5@1236|Gammaproteobacteria,1XXAW@135623|Vibrionales 135623|Vibrionales C Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane frdD GO:0000104,GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0016627,GO:0044237,GO:0045333,GO:0055114 - ko:K00247 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00150,M00173 R02164 RC00045 ko00000,ko00001,ko00002 - - - Fumarate_red_D k141_18860_1 491952.Mar181_2390 4.92e-266 754.0 COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RN01@1236|Gammaproteobacteria,1XIAS@135619|Oceanospirillales 135619|Oceanospirillales S of the RND superfamily - - - ko:K07003 - - - - ko00000 - - - MMPL k141_18860_2 491952.Mar181_2392 5.75e-08 53.1 COG0654@1|root,COG0654@2|Bacteria,1MWWT@1224|Proteobacteria,1S0S0@1236|Gammaproteobacteria 1236|Gammaproteobacteria CH FAD binding domain - - 1.14.13.218 ko:K20940 ko00405,ko01130,map00405,map01130 M00835 - - ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_3 k141_917_1 1279017.AQYJ01000027_gene1639 1.02e-86 270.0 COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,1RMB9@1236|Gammaproteobacteria,464ZX@72275|Alteromonadaceae 1236|Gammaproteobacteria O ATPase with chaperone activity comM GO:0003674,GO:0003824,GO:0004176,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0042623,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - ko:K07391 - - - - ko00000 - - - ChlI,Mg_chelatase,Mg_chelatase_C k141_3121_1 420324.KI912043_gene4038 1.28e-115 346.0 COG5361@1|root,COG5361@2|Bacteria,1MWTW@1224|Proteobacteria,2TUR1@28211|Alphaproteobacteria,1JTAK@119045|Methylobacteriaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF1254) - - - - - - - - - - - - DUF1214,DUF1254 k141_36305_1 218284.CCDN010000001_gene1334 2.32e-127 378.0 COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HAHB@91061|Bacilli,1ZPZR@1386|Bacillus 91061|Bacilli IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II yngI - - ko:K00666 - - - - ko00000,ko01000,ko01004 - - - AMP-binding,AMP-binding_C k141_24632_3 1169144.KB910927_gene1325 2.43e-07 50.8 2E3PJ@1|root,32YMN@2|Bacteria,1VGBJ@1239|Firmicutes,4HNU4@91061|Bacilli,1ZR1J@1386|Bacillus 91061|Bacilli S Belongs to the UPF0738 family yjbL - - - - - - - - - - - - k141_6845_1 1121396.KB893112_gene1980 9.83e-07 49.3 COG1846@1|root,COG1846@2|Bacteria 2|Bacteria K DNA-binding transcription factor activity marR1 - - - - - - - - - - - MarR,MarR_2 k141_6845_3 1116375.VEJY3_21711 3.04e-19 85.5 COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,1RMVU@1236|Gammaproteobacteria,1XZTY@135623|Vibrionales 135623|Vibrionales C alcohol dehydrogenase - - - - - - - - - - - - Fe-ADH k141_32810_2 986075.CathTA2_1847 4.76e-94 286.0 COG0573@1|root,COG0573@2|Bacteria,1TSPP@1239|Firmicutes,4HC9H@91061|Bacilli 91061|Bacilli P probably responsible for the translocation of the substrate across the membrane pstC - - ko:K02037 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 k141_9277_1 42565.FP66_08370 2.67e-138 407.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria 1236|Gammaproteobacteria NT chemotaxis, protein tap GO:0001101,GO:0001932,GO:0003674,GO:0004888,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006928,GO:0006935,GO:0007154,GO:0007165,GO:0007172,GO:0008104,GO:0008150,GO:0009593,GO:0009605,GO:0009719,GO:0009893,GO:0009966,GO:0009987,GO:0010033,GO:0010243,GO:0010604,GO:0010646,GO:0016020,GO:0016021,GO:0016043,GO:0019220,GO:0019222,GO:0019899,GO:0019900,GO:0019901,GO:0022607,GO:0023051,GO:0023052,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031399,GO:0031401,GO:0032101,GO:0032110,GO:0032268,GO:0032270,GO:0032879,GO:0032991,GO:0033036,GO:0034613,GO:0034622,GO:0038023,GO:0040011,GO:0040012,GO:0042221,GO:0042325,GO:0042330,GO:0042802,GO:0042803,GO:0043113,GO:0043200,GO:0043424,GO:0043549,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045859,GO:0046983,GO:0048518,GO:0048522,GO:0048583,GO:0048870,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0050920,GO:0051171,GO:0051173,GO:0051174,GO:0051179,GO:0051246,GO:0051247,GO:0051259,GO:0051260,GO:0051270,GO:0051338,GO:0051606,GO:0051641,GO:0051668,GO:0051674,GO:0051716,GO:0060089,GO:0060255,GO:0065003,GO:0065007,GO:0065009,GO:0070727,GO:0070887,GO:0071229,GO:0071230,GO:0071310,GO:0071417,GO:0071495,GO:0071840,GO:0071944,GO:0072657,GO:0080090,GO:0098561,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901873,GO:1901875,GO:1902021,GO:2000145 - ko:K03406,ko:K05874,ko:K05875,ko:K05876,ko:K05877 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal,TarH k141_34117_2 223926.28809950 2.5e-104 312.0 COG1344@1|root,COG1344@2|Bacteria,1MV1N@1224|Proteobacteria,1RYIJ@1236|Gammaproteobacteria,1XUYM@135623|Vibrionales 135623|Vibrionales N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella hag GO:0005575,GO:0005576,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 - - - ko00000,ko00001,ko02035 - - - Flagellin_C,Flagellin_N k141_10414_1 1121938.AUDY01000011_gene596 2.18e-103 302.0 COG2120@1|root,COG2120@2|Bacteria,1UZDV@1239|Firmicutes,4HE79@91061|Bacilli 91061|Bacilli S GlcNAc-PI de-N-acetylase - - - - - - - - - - - - PIG-L k141_7915_1 1347086.CCBA010000022_gene2867 3.46e-18 86.7 COG1404@1|root,COG1404@2|Bacteria,1TSRI@1239|Firmicutes,4HBFB@91061|Bacilli,1ZCQD@1386|Bacillus 91061|Bacilli O Subtilase family - - 3.4.21.62 ko:K01342 ko02024,map02024 - - - ko00000,ko00001,ko01000,ko01002,ko03110 - - - Peptidase_S8 k141_35382_2 313596.RB2501_08105 7.49e-07 53.9 COG0612@1|root,COG0612@2|Bacteria,4NEPT@976|Bacteroidetes,1HWQI@117743|Flavobacteriia 976|Bacteroidetes S Peptidase M16 - - - - - - - - - - - - Peptidase_M16,Peptidase_M16_C k141_31496_2 1042377.AFPJ01000028_gene2210 2.83e-248 706.0 COG0834@1|root,COG4623@1|root,COG0834@2|Bacteria,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,1RM8W@1236|Gammaproteobacteria,467JF@72275|Alteromonadaceae 1236|Gammaproteobacteria EMT Bacterial periplasmic substrate-binding proteins - GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - ko:K18691 - - - - ko00000,ko01000,ko01011 - - - SBP_bac_3,SLT k141_22260_1 93220.LV28_07920 1.3e-19 93.6 COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,2VNZZ@28216|Betaproteobacteria,1KFVY@119060|Burkholderiaceae 28216|Betaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - GGDEF k141_22260_3 754436.JCM19237_3619 6.34e-90 273.0 COG0265@1|root,COG0265@2|Bacteria,1R9ZV@1224|Proteobacteria,1S2AZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria O peptidase S1 and S6, chymotrypsin Hap - - - - - - - - - - - - Trypsin_2 k141_22260_4 1537994.JQFW01000015_gene1551 2.35e-69 256.0 COG0457@1|root,COG0457@2|Bacteria,1MXMD@1224|Proteobacteria,1RSI5@1236|Gammaproteobacteria,46696@72275|Alteromonadaceae 1236|Gammaproteobacteria G COG0457 FOG TPR repeat - - - - - - - - - - - - TPR_16,TPR_19,TPR_8 k141_22260_5 1085623.GNIT_2529 5.2e-76 255.0 COG5653@1|root,COG5653@2|Bacteria,1RINE@1224|Proteobacteria,1S23E@1236|Gammaproteobacteria,467IB@72275|Alteromonadaceae 1236|Gammaproteobacteria M Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_6 k141_22260_6 754436.JCM19237_3632 3.09e-77 257.0 COG2244@1|root,COG2244@2|Bacteria,1MUMD@1224|Proteobacteria,1SYZR@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Membrane protein involved in the export of O-antigen and teichoic acid - - - ko:K03328 - - - - ko00000 2.A.66.2 - - Polysacc_synt_3,Polysacc_synt_C k141_22260_7 1120953.AUBH01000014_gene2529 9.11e-141 428.0 COG0394@1|root,COG3919@1|root,COG0394@2|Bacteria,COG3919@2|Bacteria,1R94Z@1224|Proteobacteria,1RQ74@1236|Gammaproteobacteria,4666F@72275|Alteromonadaceae 1236|Gammaproteobacteria T ATP-grasp - - - - - - - - - - - - CPSase_L_D2,LMWPc k141_22260_8 1120953.AUBH01000014_gene2530 1.03e-94 290.0 COG0726@1|root,COG0726@2|Bacteria,1MX6K@1224|Proteobacteria,1RYP1@1236|Gammaproteobacteria,464GV@72275|Alteromonadaceae 1236|Gammaproteobacteria G Lipopolysaccharide biosynthesis protein walW - - - - - - - - - - - - k141_22260_9 1129794.C427_4219 3.37e-45 172.0 COG2244@1|root,COG2244@2|Bacteria,1MUMD@1224|Proteobacteria,1SYZR@1236|Gammaproteobacteria,466JZ@72275|Alteromonadaceae 1236|Gammaproteobacteria S Membrane protein involved in the export of O-antigen and teichoic acid - - - ko:K03328 - - - - ko00000 2.A.66.2 - - Polysacc_synt_3,Polysacc_synt_C k141_22260_10 944564.HMPREF9200_0605 4.66e-28 119.0 COG1215@1|root,COG1215@2|Bacteria,1V0TF@1239|Firmicutes,4H9H7@909932|Negativicutes 909932|Negativicutes M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 k141_22260_11 765913.ThidrDRAFT_4501 5.37e-66 213.0 2CPZ1@1|root,32SK5@2|Bacteria,1N2AX@1224|Proteobacteria,1SAFH@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_16252_1 498211.CJA_1346 6.06e-59 197.0 COG1611@1|root,COG1611@2|Bacteria,1MVQJ@1224|Proteobacteria,1RQHX@1236|Gammaproteobacteria,1FGKN@10|Cellvibrio 1236|Gammaproteobacteria S Domain of unknown function (DUF4478) ygdH GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016787,GO:0016798,GO:0016799,GO:0044424,GO:0044444,GO:0044464,GO:0047405 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - DUF3412,DUF4478,Lysine_decarbox k141_1881_1 251221.35210715 3.26e-58 189.0 COG3039@1|root,COG3039@2|Bacteria,1G1EK@1117|Cyanobacteria 1117|Cyanobacteria L PFAM Transposase DDE domain - - - - - - - - - - - - DDE_Tnp_1_3 k141_34118_2 218284.CCDN010000002_gene2855 1.13e-46 167.0 COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1TQ0B@1239|Firmicutes,4HA4G@91061|Bacilli,1ZBFF@1386|Bacillus 91061|Bacilli E glutamate synthase gltA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14,1.4.7.1 ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 - R00021,R00093,R00114,R00248,R10086 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - GATase_2,GXGXG,Glu_syn_central,Glu_synthase k141_18861_1 665952.HMPREF1015_01874 1.96e-10 57.0 2AWIN@1|root,31NF9@2|Bacteria,1TV4F@1239|Firmicutes,4IINS@91061|Bacilli,1ZJ38@1386|Bacillus 91061|Bacilli S YyzF-like protein - - - - - - - - - - - - YyzF k141_18861_2 997296.PB1_07477 9.44e-176 499.0 COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,4HA31@91061|Bacilli,1ZBNF@1386|Bacillus 91061|Bacilli O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain yyxA - 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Trypsin_2 k141_36306_1 218284.CCDN010000002_gene2898 2.3e-92 279.0 COG0697@1|root,COG0697@2|Bacteria,1TR8G@1239|Firmicutes,4HCXB@91061|Bacilli,1ZC8D@1386|Bacillus 91061|Bacilli EG EamA-like transporter family - - - - - - - - - - - - EamA k141_15020_1 315749.Bcer98_3600 1.48e-101 302.0 COG0506@1|root,COG0506@2|Bacteria,1TQV3@1239|Firmicutes,4HAC1@91061|Bacilli,1ZB5G@1386|Bacillus 91061|Bacilli E Proline dehydrogenase fadM GO:0000166,GO:0003674,GO:0003824,GO:0004657,GO:0005488,GO:0006082,GO:0006520,GO:0006560,GO:0006562,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016491,GO:0016645,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 - ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 - R10507 RC00083 ko00000,ko00001,ko01000 - - - Pro_dh k141_23604_1 1116375.VEJY3_22476 1.57e-213 590.0 COG3608@1|root,COG3608@2|Bacteria,1QUH0@1224|Proteobacteria,1RNXD@1236|Gammaproteobacteria,1XTMP@135623|Vibrionales 135623|Vibrionales S Succinylglutamate desuccinylase / Aspartoacylase family - - - - - - - - - - - - AstE_AspA,Peptidase_M14 k141_23604_2 945550.VISI1226_06948 3.19e-137 416.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMV2@1236|Gammaproteobacteria,1XSAN@135623|Vibrionales 135623|Vibrionales T methyl-accepting chemotaxis protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - MCPsignal,sCache_2 k141_23604_3 945550.VISI1226_22065 2.22e-81 243.0 COG1764@1|root,COG1764@2|Bacteria,1RD1A@1224|Proteobacteria,1S3UA@1236|Gammaproteobacteria,1XWVK@135623|Vibrionales 135623|Vibrionales O redox protein, regulator of disulfide bond formation - - - - - - - - - - - - OsmC k141_23604_4 945543.VIBR0546_15681 1.58e-79 239.0 COG1846@1|root,COG1846@2|Bacteria,1RH1F@1224|Proteobacteria,1S8WM@1236|Gammaproteobacteria,1XXDE@135623|Vibrionales 135623|Vibrionales K COG1846 Transcriptional regulators ohrR - - - - - - - - - - - MarR k141_23604_6 56107.Cylst_3188 1.48e-97 297.0 COG0451@1|root,COG0451@2|Bacteria,1G0QH@1117|Cyanobacteria,1HJ5Z@1161|Nostocales 1117|Cyanobacteria M PFAM NAD dependent epimerase dehydratase family rfbB - 4.1.1.35,4.2.1.46 ko:K01710,ko:K08678 ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00520,map00521,map00523,map00525,map01055,map01100,map01130 M00361,M00793 R01384,R06513 RC00402,RC00508 ko00000,ko00001,ko00002,ko01000 - - - GDP_Man_Dehyd k141_23604_7 1220583.GOACH_03_02580 1.28e-10 69.7 COG1216@1|root,COG1216@2|Bacteria,2HX2U@201174|Actinobacteria,4GC8X@85026|Gordoniaceae 201174|Actinobacteria S Glycosyl transferase family 21 - - - - - - - - - - - - Glycos_transf_2 k141_24634_1 1122599.AUGR01000018_gene3982 4.06e-41 145.0 COG0176@1|root,COG0176@2|Bacteria,1MWQ8@1224|Proteobacteria,1RMS0@1236|Gammaproteobacteria,1XH91@135619|Oceanospirillales 135619|Oceanospirillales G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway tal GO:0003674,GO:0003824,GO:0004801,GO:0016740,GO:0016744 2.2.1.2 ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01827 RC00439,RC00604 ko00000,ko00001,ko00002,ko01000 - - - TAL_FSA k141_919_1 1294265.JCM21738_1939 7.85e-151 439.0 COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,4HAMK@91061|Bacilli,1ZBB4@1386|Bacillus 91061|Bacilli E ABC transporter substrate-binding protein oppA - - ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 k141_9279_1 218284.CCDN010000004_gene3061 1.06e-154 449.0 COG0018@1|root,COG0018@2|Bacteria,1TPEZ@1239|Firmicutes,4HAR3@91061|Bacilli,1ZBP1@1386|Bacillus 91061|Bacilli J Arginyl-tRNA synthetase argS GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d k141_30324_1 1042377.AFPJ01000017_gene21 2.11e-12 66.6 COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,1SYC8@1236|Gammaproteobacteria,46AMB@72275|Alteromonadaceae 1236|Gammaproteobacteria P Sulfate permease family - - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - STAS,Sulfate_transp k141_30324_2 1453501.JELR01000001_gene2605 2.05e-70 232.0 COG0210@1|root,COG0210@2|Bacteria,1MXWE@1224|Proteobacteria,1RP5D@1236|Gammaproteobacteria,466UN@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG0210 Superfamily I DNA and RNA helicases uvrD-2 - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C k141_3123_1 1123279.ATUS01000001_gene2475 1.36e-59 198.0 COG0642@1|root,COG0642@2|Bacteria,1QTSX@1224|Proteobacteria,1T1G3@1236|Gammaproteobacteria,1JC2S@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria T Two-component sensor kinase N-terminal qseC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 ko:K07645 ko02020,ko02024,map02020,map02024 M00453 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - 2CSK_N,HATPase_c,HisKA k141_5706_1 1348635.BBJY01000021_gene2854 3.4e-87 306.0 COG1664@1|root,COG1664@2|Bacteria,1QYNH@1224|Proteobacteria,1T3SN@1236|Gammaproteobacteria,1Y36Y@135623|Vibrionales 135623|Vibrionales M Polymer-forming cytoskeletal - - - ko:K12287 - - - - ko00000,ko02044 - - - - k141_5712_7 1453501.JELR01000002_gene509 2.82e-173 491.0 COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,1RMTM@1236|Gammaproteobacteria,4659J@72275|Alteromonadaceae 1236|Gammaproteobacteria F Belongs to the D-alanine--D-alanine ligase family ddl GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008716,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - iAF1260.b0381,iB21_1397.B21_00332,iBWG_1329.BWG_0265,iE2348C_1286.E2348C_0317,iEC042_1314.EC042_0413,iEC55989_1330.EC55989_0386,iECBD_1354.ECBD_3283,iECB_1328.ECB_00328,iECDH10B_1368.ECDH10B_0338,iECDH1ME8569_1439.ECDH1ME8569_0367,iECD_1391.ECD_00328,iECH74115_1262.ECH74115_0453,iECIAI1_1343.ECIAI1_0377,iECIAI39_1322.ECIAI39_0301,iECO103_1326.ECO103_0356,iECO111_1330.ECO111_0411,iECO26_1355.ECO26_0414,iECSE_1348.ECSE_0401,iECSP_1301.ECSP_0441,iECs_1301.ECs0431,iETEC_1333.ETEC_0434,iEcDH1_1363.EcDH1_3227,iEcE24377_1341.EcE24377A_0406,iEcHS_1320.EcHS_A0447,iEcSMS35_1347.EcSMS35_0410,iEcolC_1368.EcolC_3251,iJO1366.b0381,iJR904.b0381,iSF_1195.SF0232,iSFxv_1172.SFxv_0245,iS_1188.S0254,iUMNK88_1353.UMNK88_429,iY75_1357.Y75_RS01965,iZ_1308.Z0477 Dala_Dala_lig_C,Dala_Dala_lig_N k141_27320_1 1515746.HR45_08640 2.22e-28 113.0 COG3203@1|root,COG3203@2|Bacteria,1Q1XX@1224|Proteobacteria,1S7RC@1236|Gammaproteobacteria,2QB23@267890|Shewanellaceae 1236|Gammaproteobacteria M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - - - - - - - - - - Porin_4 k141_27320_2 1238182.C882_1585 4.3e-09 60.8 COG3420@1|root,COG3420@2|Bacteria,1R629@1224|Proteobacteria,2URG7@28211|Alphaproteobacteria 28211|Alphaproteobacteria P alginic acid biosynthetic process - - - - - - - - - - - - - k141_14216_1 1279017.AQYJ01000028_gene2074 5.46e-210 616.0 COG1729@1|root,COG1729@2|Bacteria,1MX82@1224|Proteobacteria,1T32S@1236|Gammaproteobacteria,465Q0@72275|Alteromonadaceae 1236|Gammaproteobacteria O protein conserved in bacteria - - - - - - - - - - - - TPR_16,TPR_6,TPR_8,YfiO k141_36330_1 218284.CCDN010000001_gene573 7.32e-251 700.0 COG0322@1|root,COG0322@2|Bacteria,1TP4B@1239|Firmicutes,4H9QH@91061|Bacilli,1ZBY1@1386|Bacillus 91061|Bacilli L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision uvrC - - ko:K03703 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N k141_29317_1 1116375.VEJY3_19286 1.59e-260 723.0 COG4670@1|root,COG4670@2|Bacteria,1MUJW@1224|Proteobacteria,1RP80@1236|Gammaproteobacteria,1Y251@135623|Vibrionales 135623|Vibrionales I CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons - - 2.8.3.1 ko:K01026 ko00620,ko00640,ko00643,ko01100,ko01120,map00620,map00640,map00643,map01100,map01120 - R00928,R01449,R05508 RC00012,RC00014,RC00137 ko00000,ko00001,ko01000 - - - CoA_trans k141_17384_1 1408310.JHUW01000006_gene790 6.32e-15 79.7 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,4NDVA@976|Bacteroidetes,2FM8X@200643|Bacteroidia 976|Bacteroidetes L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k141_10424_1 632245.CLP_0940 6.26e-21 94.0 COG0398@1|root,COG0398@2|Bacteria,1VIUW@1239|Firmicutes,24TJI@186801|Clostridia,36N7S@31979|Clostridiaceae 186801|Clostridia S SNARE associated Golgi protein - - - - - - - - - - - - SNARE_assoc k141_18910_1 218284.CCDN010000005_gene3426 1.92e-70 223.0 COG1252@1|root,COG1252@2|Bacteria,1TR6X@1239|Firmicutes,4HA14@91061|Bacilli,1ZAV9@1386|Bacillus 91061|Bacilli C NADH dehydrogenase yumB GO:0003674,GO:0003824,GO:0003955,GO:0006091,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0019646,GO:0022900,GO:0022904,GO:0044237,GO:0045333,GO:0055114 1.6.99.3 ko:K03885 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - iYO844.BSU32100 Pyr_redox_2 k141_3146_1 218284.CCDN010000006_gene3580 3.19e-191 529.0 COG3403@1|root,COG3403@2|Bacteria,1US5K@1239|Firmicutes,4HD46@91061|Bacilli,1ZQUK@1386|Bacillus 91061|Bacilli G YqcI/YcgG family - - - ko:K09190 - - - - ko00000 - - - YqcI_YcgG k141_23639_1 1042377.AFPJ01000007_gene1858 1.02e-79 254.0 COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria,465QV@72275|Alteromonadaceae 1236|Gammaproteobacteria V Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation msbA GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006855,GO:0006869,GO:0008144,GO:0008150,GO:0008289,GO:0008559,GO:0009987,GO:0010876,GO:0015221,GO:0015238,GO:0015399,GO:0015405,GO:0015437,GO:0015893,GO:0015920,GO:0016020,GO:0016021,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0034040,GO:0034204,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0042626,GO:0042802,GO:0042908,GO:0042910,GO:0043167,GO:0043168,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0061024,GO:0065007,GO:0065008,GO:0071702,GO:0071840,GO:0071944,GO:0097035,GO:0097159,GO:0097367,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901265,GO:1901363,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - ko:K11085 ko02010,map02010 - - - ko00000,ko00001,ko01000,ko02000 3.A.1.106 - iJN746.PP_4935,iPC815.YPO1395,iUMN146_1321.UM146_12980 ABC_membrane,ABC_tran k141_16268_1 941449.dsx2_3431 1.51e-85 263.0 COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,42M67@68525|delta/epsilon subdivisions,2WJQX@28221|Deltaproteobacteria,2M9RZ@213115|Desulfovibrionales 28221|Deltaproteobacteria E PFAM Cys Met metabolism - - 2.5.1.48 ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017 R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946 RC00020,RC00056,RC00069,RC00420,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000 - - - Cys_Met_Meta_PP k141_33138_1 1042377.AFPJ01000037_gene2991 1.07e-77 241.0 COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,1RMCV@1236|Gammaproteobacteria,464GC@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide metZ - 4.4.1.11 ko:K01761,ko:K10764 ko00270,ko00450,ko00920,ko01100,map00270,map00450,map00920,map01100 - R00654,R01288,R04770 RC00020,RC00196,RC00348,RC01209,RC01210,RC02848 ko00000,ko00001,ko01000 - - - Cys_Met_Meta_PP k141_33138_2 1042377.AFPJ01000037_gene2990 1.44e-42 147.0 COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,1RP45@1236|Gammaproteobacteria,464EU@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0714 MoxR-like ATPases moxR - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 k141_36532_1 218284.CCDN010000001_gene1024 2.11e-147 421.0 COG1073@1|root,COG1073@2|Bacteria,1TQYU@1239|Firmicutes,4HC4H@91061|Bacilli,1ZBDV@1386|Bacillus 91061|Bacilli S COG1073 Hydrolases of the alpha beta superfamily yqkD - - ko:K06889 - - - - ko00000 - - - Hydrolase_4 k141_16551_1 1294265.JCM21738_1799 1.61e-107 315.0 COG0561@1|root,COG0561@2|Bacteria,1V5FB@1239|Firmicutes,4HGY8@91061|Bacilli,1ZDBI@1386|Bacillus 91061|Bacilli S hydrolases of the HAD superfamily ycsE - - - - - - - - - - - Hydrolase_3 k141_8057_1 674977.VMC_19720 7.44e-232 639.0 COG2113@1|root,COG2113@2|Bacteria,1MWZU@1224|Proteobacteria,1RNDF@1236|Gammaproteobacteria,1XUND@135623|Vibrionales 135623|Vibrionales E Substrate binding domain of ABC-type glycine betaine transport system proX - - ko:K02002 ko02010,map02010 M00208 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - OpuAC k141_8057_2 1116375.VEJY3_08000 2.43e-229 634.0 COG4176@1|root,COG4176@2|Bacteria,1MUM4@1224|Proteobacteria,1RPQS@1236|Gammaproteobacteria,1XTMM@135623|Vibrionales 135623|Vibrionales P COG4176 ABC-type proline glycine betaine transport system, permease component proW - - ko:K02001 ko02010,map02010 M00208 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - BPD_transp_1 k141_2199_2 1453501.JELR01000002_gene65 4.08e-143 410.0 COG0720@1|root,COG0720@2|Bacteria,1MXVT@1224|Proteobacteria,1RN6H@1236|Gammaproteobacteria,464QP@72275|Alteromonadaceae 1236|Gammaproteobacteria H COG0720 6-pyruvoyl-tetrahydropterin synthase SO2179 - 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 - - - PTPS k141_2199_3 1279017.AQYJ01000021_gene2795 1.68e-161 471.0 COG1164@1|root,COG1164@2|Bacteria,1MWYN@1224|Proteobacteria,1RS2Q@1236|Gammaproteobacteria,465UB@72275|Alteromonadaceae 1236|Gammaproteobacteria E Angiotensin-converting enzyme - - 3.4.15.1 ko:K01283 ko04614,ko04924,ko05142,ko05410,map04614,map04924,map05142,map05410 - - - ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 - - - Peptidase_M2 k141_31689_1 218284.CCDN010000001_gene614 7.12e-141 412.0 COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,4HB0C@91061|Bacilli,1ZD5J@1386|Bacillus 91061|Bacilli NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB pilB - - ko:K02243,ko:K02652 - M00429 - - ko00000,ko00002,ko02035,ko02044 3.A.14.1,3.A.15.2 - - T2SSE,T2SSE_N k141_29697_2 1033734.CAET01000048_gene1643 2.08e-29 105.0 COG1942@1|root,COG1942@2|Bacteria,1VKD5@1239|Firmicutes,4HRBS@91061|Bacilli,1ZITA@1386|Bacillus 91061|Bacilli G 4-oxalocrotonate tautomerase dmpI GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0044237 5.3.2.6 ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 M00569 R03966,R05389 RC01040,RC01355 ko00000,ko00001,ko00002,ko01000 - - - Tautomerase k141_36533_1 218284.CCDN010000001_gene1804 8.38e-103 319.0 COG2366@1|root,COG2366@2|Bacteria,1UFHA@1239|Firmicutes,4HACM@91061|Bacilli,1ZCMT@1386|Bacillus 91061|Bacilli S Penicillin amidase acyII - 3.5.1.11 ko:K01434 ko00311,ko01130,map00311,map01130 - R02170 RC00166,RC00328 ko00000,ko00001,ko01000,ko01002 - - - Penicil_amidase k141_34408_1 1307436.PBF_06028 9.37e-217 616.0 COG0243@1|root,COG0243@2|Bacteria,1TPZG@1239|Firmicutes,4HBA3@91061|Bacilli,1ZAU8@1386|Bacillus 91061|Bacilli C belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - - - - - - - - - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding k141_21203_1 1116375.VEJY3_02855 0.0 949.0 COG1115@1|root,COG1115@2|Bacteria,1MUI3@1224|Proteobacteria,1RMNF@1236|Gammaproteobacteria,1XU2Z@135623|Vibrionales 135623|Vibrionales U COG1115 Na alanine symporter - - - ko:K03310 - - - - ko00000 2.A.25 - - Na_Ala_symp k141_21203_2 1116375.VEJY3_02860 5.41e-292 798.0 COG0665@1|root,COG0665@2|Bacteria,1MVIZ@1224|Proteobacteria,1RQ50@1236|Gammaproteobacteria,1XVCU@135623|Vibrionales 135623|Vibrionales C Oxidative deamination of D-amino acids dadA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0008150,GO:0008152,GO:0008718,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009324,GO:0009987,GO:0016020,GO:0016054,GO:0016491,GO:0016638,GO:0019478,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046144,GO:0046395,GO:0046416,GO:0046436,GO:0055114,GO:0055130,GO:0071704,GO:0071944,GO:0098796,GO:0098797,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902494,GO:1990204 1.4.5.1 ko:K00285 ko00360,map00360 - R01374,R09493 RC00006,RC00025 ko00000,ko00001,ko01000 - - - DAO k141_21203_3 1116375.VEJY3_02865 1.39e-118 345.0 COG0583@1|root,COG0583@2|Bacteria,1MV11@1224|Proteobacteria,1SYIC@1236|Gammaproteobacteria,1XSMV@135623|Vibrionales 135623|Vibrionales K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_15248_2 1279017.AQYJ01000027_gene1985 4.72e-118 341.0 COG0118@1|root,COG0118@2|Bacteria,1MU4X@1224|Proteobacteria,1RRP3@1236|Gammaproteobacteria,465J2@72275|Alteromonadaceae 1236|Gammaproteobacteria E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR hisH GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - - GATase k141_28248_1 1453501.JELR01000002_gene786 1.73e-157 447.0 COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,1RMHW@1236|Gammaproteobacteria,464VH@72275|Alteromonadaceae 1236|Gammaproteobacteria J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits ksgA GO:0000028,GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003723,GO:0003729,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0031167,GO:0032259,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043412,GO:0043414,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070475,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140102,GO:1901360,GO:1901363 2.1.1.182 ko:K02528 - - R10716 RC00003,RC03257 ko00000,ko01000,ko03009 - - - RrnaAD k141_37835_1 748449.Halha_1929 1.28e-28 119.0 COG2274@1|root,COG2274@2|Bacteria,1V77J@1239|Firmicutes,25E7C@186801|Clostridia,3WCBY@53433|Halanaerobiales 186801|Clostridia V Peptidase C39 family lagD - - ko:K20344 ko02010,ko02024,map02010,map02024 - - - ko00000,ko00001,ko02000 3.A.1.112 - - ABC_membrane,ABC_tran,Peptidase_C39 k141_33141_1 218284.CCDN010000002_gene2278 5.78e-128 369.0 COG1131@1|root,COG1131@2|Bacteria,1TPMQ@1239|Firmicutes,4HA8K@91061|Bacilli,1ZAYW@1386|Bacillus 91061|Bacilli V COG1131 ABC-type multidrug transport system, ATPase component - - - ko:K01990,ko:K11050 ko02010,map02010 M00254,M00298 - - ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.130 - - ABC_tran k141_30535_2 373126.Q2A0C1_9VIRU 2.95e-13 70.1 4QD9Y@10239|Viruses 10239|Viruses S Pfam:Terminase_6C - - - - - - - - - - - - - k141_34410_1 1294265.JCM21738_5462 2e-80 239.0 COG0346@1|root,COG0346@2|Bacteria,1VCGT@1239|Firmicutes,4HKDV@91061|Bacilli,1ZGXG@1386|Bacillus 91061|Bacilli E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - Glyoxalase k141_4615_1 1279017.AQYJ01000022_gene2721 5.84e-170 504.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria,465ZZ@72275|Alteromonadaceae 1236|Gammaproteobacteria P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec k141_4615_2 1280950.HJO_04335 5.54e-25 105.0 COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,2U099@28211|Alphaproteobacteria,440NK@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Sulfotransferase domain - - - - - - - - - - - - Sulfotransfer_3,TPR_2,TPR_8 k141_28249_1 1462526.BN990_03805 1.9e-136 388.0 COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,4HAK4@91061|Bacilli,4C5GN@84406|Virgibacillus 91061|Bacilli J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release rplA GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02863 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L1 k141_3421_1 1131730.BAVI_12744 2.45e-19 86.3 COG0477@1|root,COG2814@2|Bacteria,1TSFM@1239|Firmicutes,4HABN@91061|Bacilli,1ZS92@1386|Bacillus 91061|Bacilli EGP COG0477 Permeases of the major facilitator superfamily yqjV - - - - - - - - - - - MFS_1,MFS_1_like,Sugar_tr k141_3421_2 1307436.PBF_01950 4.12e-54 176.0 COG1360@1|root,COG1360@2|Bacteria,1UXY4@1239|Firmicutes,4HCCI@91061|Bacilli,1ZB4F@1386|Bacillus 91061|Bacilli N Flagellar motor protein motB - - ko:K02557 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - MotB_plug,OmpA k141_21205_1 1042377.AFPJ01000004_gene397 3.68e-82 257.0 COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,1RN3V@1236|Gammaproteobacteria,463ZU@72275|Alteromonadaceae 1236|Gammaproteobacteria FP Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the stringent response , an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities gppA - 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 - R03409 RC00002 ko00000,ko00001,ko01000 - - - HD,Ppx-GppA k141_21205_2 1042377.AFPJ01000004_gene396 1.43e-71 229.0 COG0397@1|root,COG0397@2|Bacteria,1MVK3@1224|Proteobacteria,1RNCS@1236|Gammaproteobacteria,4646G@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the UPF0061 (SELO) family ydiU - - ko:K08997 - - - - ko00000 - - - UPF0061 k141_10646_1 1121439.dsat_0474 7e-33 132.0 COG0471@1|root,COG0490@1|root,COG0471@2|Bacteria,COG0490@2|Bacteria,1MU0K@1224|Proteobacteria,42MR7@68525|delta/epsilon subdivisions,2WIKA@28221|Deltaproteobacteria,2M9JU@213115|Desulfovibrionales 28221|Deltaproteobacteria P PFAM Citrate transporter - - - - - - - - - - - - CitMHS,Na_sulph_symp,TrkA_C k141_33142_1 218284.CCDN010000001_gene1793 2.71e-44 145.0 COG1388@1|root,COG1388@2|Bacteria 2|Bacteria M LysM domain yneA GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 - ko:K06194 - - - - ko00000 1.A.34.1.2 - - LysM,OapA,Peptidase_M23 k141_30536_1 1294265.JCM21738_2551 1.4e-73 225.0 COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,4H9S9@91061|Bacilli,1ZCVZ@1386|Bacillus 91061|Bacilli E Methionine aminopeptidase map_1 - 3.4.11.18 ko:K01265 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M24 k141_8061_1 218284.CCDN010000006_gene3730 9.14e-142 437.0 COG2247@1|root,COG2374@1|root,COG2247@2|Bacteria,COG2374@2|Bacteria,1VKCH@1239|Firmicutes,4IS68@91061|Bacilli,1ZS2A@1386|Bacillus 91061|Bacilli M Fn3 associated XK27_02140 - - ko:K07004 - - - - ko00000 - - - CHB_HEX_C_1,Exo_endo_phos,Fn3_assoc,Gram_pos_anchor,LTD,SLH k141_36536_1 218284.CCDN010000005_gene3471 8.46e-167 473.0 COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,4HA2Y@91061|Bacilli,1ZAV3@1386|Bacillus 91061|Bacilli E Catalyzes the interconversion of ornithine to glutamate semialdehyde rocD GO:0003674,GO:0003824,GO:0004587,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009064,GO:0009987,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901605 2.6.1.13 ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 - R00667 RC00006,RC00062 ko00000,ko00001,ko01000,ko01007 - - iYO844.BSU40340 Aminotran_3 k141_10679_1 42565.FP66_11470 1.61e-130 380.0 COG3486@1|root,COG3486@2|Bacteria,1MX36@1224|Proteobacteria,1RNB9@1236|Gammaproteobacteria,1XJRU@135619|Oceanospirillales 135619|Oceanospirillales Q L-lysine 6-monooxygenase (NADPH-requiring) - - 1.14.13.59 ko:K03897 ko00310,ko01120,map00310,map01120 - R00448 RC00298 ko00000,ko00001,ko01000 - - - K_oxygenase k141_8083_1 218284.CCDN010000002_gene2232 8.21e-50 169.0 COG3486@1|root,COG3486@2|Bacteria,1UZAQ@1239|Firmicutes,4HBWJ@91061|Bacilli,1ZB3E@1386|Bacillus 91061|Bacilli Q L-lysine 6-monooxygenase (NADPH-requiring) - - 1.14.13.59 ko:K03897 ko00310,ko01120,map00310,map01120 - R00448 RC00298 ko00000,ko00001,ko01000 - - - K_oxygenase k141_10680_1 1144275.COCOR_05185 4.3e-49 166.0 COG0596@1|root,COG0596@2|Bacteria,1R4N4@1224|Proteobacteria,434SV@68525|delta/epsilon subdivisions,2WZ3Y@28221|Deltaproteobacteria,2Z19T@29|Myxococcales 28221|Deltaproteobacteria S Hydrolase - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 k141_28286_1 223926.28807713 3.57e-135 388.0 COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,1RMI0@1236|Gammaproteobacteria,1XTNY@135623|Vibrionales 135623|Vibrionales U MSHA biogenesis protein MshM mshM - - ko:K12283 - - - - ko00000,ko02044 - - - AAA_22 k141_28286_2 1116375.VEJY3_13850 5.16e-103 311.0 COG0457@1|root,COG0457@2|Bacteria,1N260@1224|Proteobacteria,1S9QX@1236|Gammaproteobacteria,1XSRE@135623|Vibrionales 135623|Vibrionales S MSHA biogenesis protein MshN mshN - - ko:K12284 - - - - ko00000,ko02044 - - - TPR_16,TPR_19 k141_3458_1 1042377.AFPJ01000021_gene2141 1.42e-25 99.4 COG3245@1|root,COG3245@2|Bacteria,1MZBZ@1224|Proteobacteria,1S9Z9@1236|Gammaproteobacteria 1236|Gammaproteobacteria C cytochrome c5 cyc - 1.9.3.1 ko:K02277 ko00190,ko01100,map00190,map01100 M00155 - - ko00000,ko00001,ko00002,ko01000 3.D.4.4 - - Cytochrome_CBB3 k141_3458_2 1279017.AQYJ01000026_gene393 1.16e-56 184.0 COG0476@1|root,COG0476@2|Bacteria,1MW7H@1224|Proteobacteria,1RPJ3@1236|Gammaproteobacteria,466BQ@72275|Alteromonadaceae 1236|Gammaproteobacteria H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 moeB - 2.7.7.73,2.7.7.80 ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07459 RC00043 ko00000,ko00001,ko01000 - - - ThiF k141_15269_1 218284.CCDN010000004_gene3025 2.56e-114 331.0 COG2208@1|root,COG2208@2|Bacteria,1V0BN@1239|Firmicutes,4HECS@91061|Bacilli,1ZEVQ@1386|Bacillus 91061|Bacilli KT Sigma factor PP2C-like phosphatases rsbX GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0050896 3.1.3.3 ko:K05518 - - - - ko00000,ko01000,ko03021 - - - PP2C_2,SpoIIE k141_34437_1 1122201.AUAZ01000012_gene1331 8.32e-21 92.8 COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,1RMAY@1236|Gammaproteobacteria,464S8@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate proA GO:0003674,GO:0003824,GO:0004350,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0055114,GO:0055129,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 M00015 R03313 RC00684 ko00000,ko00001,ko00002,ko01000 - - iB21_1397.B21_00243,iECBD_1354.ECBD_3376,iECB_1328.ECB_00240,iECD_1391.ECD_00240,iYL1228.KPN_00280 Aldedh k141_34437_2 1042377.AFPJ01000030_gene461 2.18e-93 276.0 COG2802@1|root,COG2802@2|Bacteria,1NV9N@1224|Proteobacteria,1T15C@1236|Gammaproteobacteria,46D1P@72275|Alteromonadaceae 1236|Gammaproteobacteria S ATP-dependent protease La (LON) substrate-binding domain - - - ko:K07157 - - - - ko00000 - - - LON_substr_bdg k141_34437_3 1453501.JELR01000002_gene149 7.12e-149 426.0 COG2321@1|root,COG2321@2|Bacteria,1MU4U@1224|Proteobacteria,1RMF8@1236|Gammaproteobacteria,466BZ@72275|Alteromonadaceae 1236|Gammaproteobacteria S Putative neutral zinc metallopeptidase - - - ko:K07054 - - - - ko00000 - - - Zn_peptidase k141_21250_1 981383.AEWH01000043_gene1572 8.95e-47 164.0 COG0596@1|root,COG0596@2|Bacteria,1V9D7@1239|Firmicutes 1239|Firmicutes S Alpha beta hydrolase - - - - - - - - - - - - Abhydrolase_1 k141_21250_2 218284.CCDN010000001_gene1017 6.2e-107 314.0 COG4975@1|root,COG4975@2|Bacteria,1TQBN@1239|Firmicutes,4HAVH@91061|Bacilli,1ZE1R@1386|Bacillus 91061|Bacilli U Glucose uptake glcU - - ko:K05340 - - - - ko00000,ko02000 2.A.7.5 - - Sugar_transport k141_3459_2 545693.BMQ_3057 2.93e-33 124.0 COG1366@1|root,COG1366@2|Bacteria,1VWK9@1239|Firmicutes,4HW8Z@91061|Bacilli,1ZR7B@1386|Bacillus 91061|Bacilli T Belongs to the anti-sigma-factor antagonist family - - - - - - - - - - - - - k141_16579_1 218284.CCDN010000004_gene3125 3.73e-120 362.0 COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,4HADT@91061|Bacilli,1ZCKV@1386|Bacillus 91061|Bacilli KT Sigma-54 interaction domain - - - - - - - - - - - - HTH_12,HTH_8,PAS,PAS_9,Sigma54_activat k141_31730_1 1453501.JELR01000005_gene1584 4.44e-84 261.0 COG4977@1|root,COG4977@2|Bacteria,1R01Y@1224|Proteobacteria,1T4DW@1236|Gammaproteobacteria,46DE7@72275|Alteromonadaceae 1236|Gammaproteobacteria K helix_turn_helix, arabinose operon control protein - - - - - - - - - - - - HTH_18 k141_8085_1 1453501.JELR01000002_gene915 0.000252 50.4 COG3209@1|root,COG3209@2|Bacteria 2|Bacteria M self proteolysis - - - - - - - - - - - - RHS_repeat k141_28287_1 1294265.JCM21738_1859 2.33e-112 330.0 COG1879@1|root,COG1879@2|Bacteria,1TSUI@1239|Firmicutes,4HBMV@91061|Bacilli,1ZC6R@1386|Bacillus 91061|Bacilli G Periplasmic binding protein domain - - - ko:K02058 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - Peripla_BP_4 k141_21251_1 1294265.JCM21738_2118 3.79e-145 414.0 COG1041@1|root,COG1041@2|Bacteria,1TRH9@1239|Firmicutes,4HCHR@91061|Bacilli,1ZBCC@1386|Bacillus 91061|Bacilli L Putative RNA methylase family UPF0020 rumA - - - - - - - - - - - UPF0020 k141_33172_2 1279017.AQYJ01000028_gene2530 5.95e-161 453.0 COG0842@1|root,COG0842@2|Bacteria,1MUH1@1224|Proteobacteria,1RP0Z@1236|Gammaproteobacteria,465E6@72275|Alteromonadaceae 1236|Gammaproteobacteria V COG0842 ABC-type multidrug transport system, permease component yadH - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane k141_33172_3 1042377.AFPJ01000051_gene33 3.22e-154 440.0 COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,1RYRB@1236|Gammaproteobacteria,46479@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0491 Zn-dependent hydrolases, including glyoxylases - - - - - - - - - - - - Lactamase_B k141_33172_4 35754.JNYJ01000003_gene6411 4.6e-22 100.0 COG0584@1|root,COG0584@2|Bacteria,2GJ5W@201174|Actinobacteria,4DB2J@85008|Micromonosporales 201174|Actinobacteria C glycerophosphoryl diester phosphodiesterase glpQ2 - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - GDPD k141_33172_5 1453501.JELR01000002_gene402 4.46e-61 207.0 28HC9@1|root,2Z7P5@2|Bacteria,1R4BH@1224|Proteobacteria,1RSAN@1236|Gammaproteobacteria,4642U@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_2245_1 498211.CJA_3068 4.02e-84 275.0 2DB7A@1|root,2Z7KK@2|Bacteria,1PI5G@1224|Proteobacteria,1RQHS@1236|Gammaproteobacteria,1FG5B@10|Cellvibrio 1236|Gammaproteobacteria S Glycosyl hydrolase family 115 - - - - - - - - - - - - Glyco_hydro_115,Glyco_hydro_67N k141_10682_1 1122225.AULQ01000007_gene2372 6.58e-71 225.0 COG1215@1|root,COG1215@2|Bacteria,4NFUA@976|Bacteroidetes,1HY1H@117743|Flavobacteriia 976|Bacteroidetes M Glycosyl transferase family 2 - - - - - - - - - - - - Glyco_transf_7C,Glycos_transf_2 k141_10682_2 742726.HMPREF9448_01542 5.14e-11 63.2 COG3369@1|root,COG3369@2|Bacteria,4NH0R@976|Bacteroidetes,2FTPH@200643|Bacteroidia,22W7R@171551|Porphyromonadaceae 976|Bacteroidetes S CDGSH-type zinc finger. Function unknown. - - - - - - - - - - - - Fer4_19,zf-CDGSH k141_28288_1 1033734.CAET01000027_gene800 2.58e-13 70.5 COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,4H9VZ@91061|Bacilli,1ZC2Y@1386|Bacillus 91061|Bacilli E acetylornithine aminotransferase argD GO:0003674,GO:0003824,GO:0003992,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.11,2.6.1.17 ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R02283,R04475 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 k141_3460_2 471223.GWCH70_0601 4.52e-44 158.0 COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,4HA1G@91061|Bacilli,1WEKG@129337|Geobacillus 91061|Bacilli G Alpha-amylase domain yugT - 3.2.1.20 ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00028,R00801,R00802,R06087,R06088 RC00028,RC00049,RC00077 ko00000,ko00001,ko01000 - GH31 iSB619.SA_RS07580 Alpha-amylase,Malt_amylase_C k141_37878_1 324057.Pjdr2_5118 3.29e-69 219.0 COG0053@1|root,COG0053@2|Bacteria,1TP5C@1239|Firmicutes,4HAP0@91061|Bacilli,26SIV@186822|Paenibacillaceae 91061|Bacilli P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family cat - - - - - - - - - - - Cation_efflux,ZT_dimer k141_2246_1 406124.ACPC01000009_gene1398 1.08e-51 182.0 COG4191@1|root,COG4191@2|Bacteria,1VCNJ@1239|Firmicutes,4HVBX@91061|Bacilli,1ZS41@1386|Bacillus 91061|Bacilli T Histidine kinase kinA GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0009653,GO:0009987,GO:0030154,GO:0030435,GO:0032502,GO:0042802,GO:0043934,GO:0043937,GO:0043938,GO:0048518,GO:0048646,GO:0048856,GO:0048869,GO:0050789,GO:0050793,GO:0051094,GO:0065007 2.7.13.3 ko:K02491 ko02020,map02020 M00485 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,MEDS,PAS,PAS_9 k141_34440_2 344747.PM8797T_11731 0.000255 42.7 COG0861@1|root,COG0861@2|Bacteria,2IYX8@203682|Planctomycetes 203682|Planctomycetes P COG0861 Membrane protein TerC possibly involved in tellurium - - - - - - - - - - - - TerC k141_3461_1 1229780.BN381_90023 5.34e-75 251.0 COG0553@1|root,COG0553@2|Bacteria,2GISC@201174|Actinobacteria,3UX1U@52018|unclassified Actinobacteria (class) 201174|Actinobacteria L SNF2 family N-terminal domain - - - - - - - - - - - - DUF3670,Helicase_C,SNF2_N k141_10683_2 1294265.JCM21738_3296 6.44e-88 259.0 COG1610@1|root,COG1610@2|Bacteria,1V6F2@1239|Firmicutes,4HIQP@91061|Bacilli,1ZGGX@1386|Bacillus 91061|Bacilli S Yqey-like protein yqeY - - ko:K09117 - - - - ko00000 - - - YqeY k141_21252_1 1453501.JELR01000002_gene1538 3.08e-164 466.0 COG2377@1|root,COG2377@2|Bacteria,1MV4E@1224|Proteobacteria,1RNTZ@1236|Gammaproteobacteria,464CU@72275|Alteromonadaceae 1236|Gammaproteobacteria O Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling anmK GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237 2.7.1.170 ko:K09001 - - - - ko00000,ko01000 - - iECABU_c1320.ECABU_c18930,iECED1_1282.ECED1_1841,ic_1306.c2032 AnmK k141_30569_1 218284.CCDN010000002_gene2255 1.46e-84 267.0 COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,4H9SP@91061|Bacilli,1ZAPS@1386|Bacillus 91061|Bacilli P COG2217 Cation transport ATPase zosA - 3.6.3.3,3.6.3.5 ko:K01534 - - - - ko00000,ko01000 3.A.3.6 - - E1-E2_ATPase,Hydrolase k141_8088_1 1123288.SOV_4c02050 1.54e-55 180.0 COG1704@1|root,COG1704@2|Bacteria,1V3Z0@1239|Firmicutes,4H3F2@909932|Negativicutes 1239|Firmicutes S LemA family lemA2 - - ko:K03744 - - - - ko00000 - - - LemA k141_16581_1 218284.CCDN010000001_gene1779 7.08e-17 79.3 COG3852@1|root,COG3852@2|Bacteria,1TRH0@1239|Firmicutes,4HD4A@91061|Bacilli,1ZDWU@1386|Bacillus 91061|Bacilli T COG0642 Signal transduction histidine kinase kinC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 ko:K07698 ko02020,map02020 M00485 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS,PAS_3,PAS_9 k141_3462_1 1121104.AQXH01000002_gene633 3.64e-13 74.7 COG4797@1|root,COG4797@2|Bacteria,4PKQS@976|Bacteroidetes,1J10C@117747|Sphingobacteriia 976|Bacteroidetes S Motility related/secretion protein sprA - - - - - - - - - - - SprA_N k141_33175_1 518766.Rmar_2012 8.51e-77 248.0 COG4263@1|root,COG4263@2|Bacteria,4NFNE@976|Bacteroidetes,1FIVE@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes C Nitrous oxide reductase nosZ - 1.7.2.4 ko:K00376 ko00910,ko01120,map00910,map01120 M00529 R02804 RC02861 ko00000,ko00001,ko00002,ko01000 - - - - k141_10684_2 218284.CCDN010000001_gene1776 2.31e-76 239.0 COG0420@1|root,COG0420@2|Bacteria,1TQY6@1239|Firmicutes,4HAKB@91061|Bacilli,1ZBQQ@1386|Bacillus 91061|Bacilli L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity sbcD - - ko:K03547 - - - - ko00000,ko03400 - - - Metallophos,SbcD_C k141_21253_1 1122917.KB899663_gene2620 1.66e-77 246.0 COG0642@1|root,COG2205@2|Bacteria,1V10X@1239|Firmicutes,4HB4P@91061|Bacilli,26SCI@186822|Paenibacillaceae 91061|Bacilli T Histidine kinase hssS - - - - - - - - - - - HAMP,HATPase_c,HisKA k141_33176_1 218284.CCDN010000005_gene3328 9.9e-99 295.0 COG1960@1|root,COG1960@2|Bacteria,1TSN3@1239|Firmicutes,4HB0T@91061|Bacilli,1ZDR4@1386|Bacillus 91061|Bacilli I Acyl-CoA dehydrogenase, N-terminal domain - - 1.3.8.7 ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_2247_1 1211579.PP4_04690 6.98e-37 124.0 2E4EA@1|root,32Z9I@2|Bacteria,1N7HE@1224|Proteobacteria,1SDU5@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_10685_1 1453501.JELR01000002_gene681 7.98e-59 194.0 COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,1RQR7@1236|Gammaproteobacteria,4668G@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria ycbB GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0006508,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0008236,GO:0008238,GO:0009273,GO:0009987,GO:0016740,GO:0016746,GO:0016755,GO:0016787,GO:0016807,GO:0017171,GO:0019538,GO:0033554,GO:0042546,GO:0043164,GO:0043170,GO:0044036,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0050896,GO:0051716,GO:0070004,GO:0070008,GO:0070011,GO:0071554,GO:0071704,GO:0071840,GO:0071972,GO:0140096,GO:1901564 - ko:K21470 - - - - ko00000,ko01002,ko01011 - - - PG_binding_1,YkuD k141_37882_1 218284.CCDN010000001_gene90 7.32e-58 199.0 COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,4H9VQ@91061|Bacilli,1ZASE@1386|Bacillus 91061|Bacilli M Penicillin-binding Protein pbpX GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - - PASTA,PBP_dimer,Transpeptidase k141_34442_2 218284.CCDN010000002_gene2167 6.25e-50 166.0 COG1030@1|root,COG1030@2|Bacteria,1V6UR@1239|Firmicutes,4HJIN@91061|Bacilli,1ZFVS@1386|Bacillus 91061|Bacilli - - M1-693 - - - - - - - - - - - TspO_MBR k141_36582_1 1280001.BAOA01000072_gene2767 5.12e-92 271.0 COG1670@1|root,COG1670@2|Bacteria,1N18Y@1224|Proteobacteria,1S8ZQ@1236|Gammaproteobacteria,1XXBX@135623|Vibrionales 135623|Vibrionales J Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_3 k141_36582_2 1219076.N646_4355 8.02e-18 76.3 2EFSX@1|root,339IW@2|Bacteria,1NG97@1224|Proteobacteria,1SGWE@1236|Gammaproteobacteria,1XZD8@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF2986) - - - - - - - - - - - - DUF2986 k141_36582_3 1116375.VEJY3_19596 1.99e-117 342.0 2EB0W@1|root,3351S@2|Bacteria,1NDZQ@1224|Proteobacteria,1T0PA@1236|Gammaproteobacteria,1XTEG@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - FhuF_C k141_30571_2 218284.CCDN010000006_gene3731 1.81e-19 86.7 COG2978@1|root,COG2978@2|Bacteria,1TPDU@1239|Firmicutes,4HAWR@91061|Bacilli,1ZARX@1386|Bacillus 91061|Bacilli H AbgT putative transporter family - - - ko:K12942 - - - - ko00000 - - - ABG_transport k141_3463_1 218284.CCDN010000001_gene672 5.19e-209 591.0 COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,4HACD@91061|Bacilli,1ZBXI@1386|Bacillus 91061|Bacilli J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) aspS - 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - GAD,tRNA-synt_2,tRNA_anti-codon k141_14437_14 1116375.VEJY3_10595 3.88e-283 775.0 COG1940@1|root,COG1940@2|Bacteria,1MX6M@1224|Proteobacteria,1RNZ1@1236|Gammaproteobacteria,1XTAB@135623|Vibrionales 135623|Vibrionales GK COG1940 Transcriptional regulator sugar kinase mlc - - ko:K15545 - - - - ko00000,ko03000 - - - ROK k141_14437_15 223926.28807030 3.52e-205 570.0 COG0784@1|root,COG0835@1|root,COG0784@2|Bacteria,COG0835@2|Bacteria,1N81M@1224|Proteobacteria,1RPS1@1236|Gammaproteobacteria,1XT9E@135623|Vibrionales 135623|Vibrionales T COG0835 Chemotaxis signal transduction protein - - - ko:K03415 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - CheW,Response_reg k141_14437_16 1116375.VEJY3_10590 0.0 1916.0 COG0587@1|root,COG0587@2|Bacteria,1MUE4@1224|Proteobacteria,1RQA8@1236|Gammaproteobacteria,1XVW2@135623|Vibrionales 135623|Vibrionales L DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase dnaE2 - 2.7.7.7 ko:K14162 - - - - ko00000,ko01000,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon k141_14437_17 1280001.BAOA01000086_gene3544 6.15e-300 822.0 COG0389@1|root,COG0389@2|Bacteria,1MU5X@1224|Proteobacteria,1S28B@1236|Gammaproteobacteria,1XU19@135623|Vibrionales 135623|Vibrionales L Nucleotidyltransferase DNA polymerase involved in DNA repair - - - ko:K14161 - - - - ko00000,ko03400 - - - IMS k141_14437_18 1280001.BAOA01000086_gene3543 2.11e-98 289.0 COG4544@1|root,COG4544@2|Bacteria,1MZQU@1224|Proteobacteria,1S9RP@1236|Gammaproteobacteria,1XV15@135623|Vibrionales 135623|Vibrionales S COG0468 RecA RadA recombinase - - - - - - - - - - - - RecA k141_4890_1 1279017.AQYJ01000028_gene2414 2.94e-63 205.0 COG1716@1|root,COG1716@2|Bacteria,1MXT7@1224|Proteobacteria,1SAKZ@1236|Gammaproteobacteria,468KA@72275|Alteromonadaceae 1236|Gammaproteobacteria T Forkhead associated domain - - - - - - - - - - - - FHA,Yop-YscD_cpl k141_4890_2 1453501.JELR01000002_gene507 4.85e-170 485.0 COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,1RP4T@1236|Gammaproteobacteria,464SK@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily hisC - 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k141_29848_2 1285586.H131_19517 2.64e-96 300.0 COG0770@1|root,COG0770@2|Bacteria,1UPUZ@1239|Firmicutes,4HTD6@91061|Bacilli,3IXF0@400634|Lysinibacillus 91061|Bacilli M Mur ligase family, glutamate ligase domain - - 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 - R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase_C,Mur_ligase_M k141_15643_1 218284.CCDN010000002_gene2554 3.15e-87 271.0 COG4533@1|root,COG4533@2|Bacteria,1TRY2@1239|Firmicutes,4HBZ3@91061|Bacilli,1ZAUC@1386|Bacillus 91061|Bacilli S Sugar transport-related sRNA regulator N-term - - - - - - - - - - - - SBP_bac_5,SgrR_N k141_31098_1 218284.CCDN010000009_gene4275 3.8e-101 304.0 COG4856@1|root,COG4856@2|Bacteria,1TSIV@1239|Firmicutes,4HD8Y@91061|Bacilli,1ZB2T@1386|Bacillus 91061|Bacilli S protein conserved in bacteria ybbR GO:0008150,GO:0031279,GO:0031281,GO:0043085,GO:0044093,GO:0045761,GO:0045762,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009 - - - - - - - - - - YbbR k141_34630_1 1280001.BAOA01000007_gene3982 2.57e-112 347.0 COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria,1MVCT@1224|Proteobacteria,1RNP1@1236|Gammaproteobacteria,1XT2U@135623|Vibrionales 135623|Vibrionales MV ABC-type antimicrobial peptide transport system, permease component - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD k141_34630_2 1116375.VEJY3_24221 5.66e-216 602.0 COG5621@1|root,COG5621@2|Bacteria,1MUVF@1224|Proteobacteria,1RZ65@1236|Gammaproteobacteria,1XTRT@135623|Vibrionales 135623|Vibrionales S secreted hydrolase - - - - - - - - - - - - CrtC,Lipocalin_9 k141_34630_3 1116375.VEJY3_24176 1.35e-201 561.0 COG0600@1|root,COG0600@2|Bacteria,1MWDJ@1224|Proteobacteria,1RQ0A@1236|Gammaproteobacteria,1XYGU@135623|Vibrionales 135623|Vibrionales P Binding-protein-dependent transport system inner membrane component - - - ko:K15552,ko:K15554 ko00920,ko02010,map00920,map02010 M00435,M00436 - - ko00000,ko00001,ko00002,ko02000 3.A.1.17.1,3.A.1.17.2,3.A.1.17.4 - - BPD_transp_1 k141_34630_4 1116375.VEJY3_24181 9.78e-195 541.0 COG4525@1|root,COG4525@2|Bacteria,1QTUA@1224|Proteobacteria,1RPAF@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system tauB - 3.6.3.36 ko:K10831 ko00920,ko02010,map00920,map02010 M00435 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.17.1,3.A.1.17.4 - - ABC_tran k141_34630_5 1116375.VEJY3_24186 1.45e-233 644.0 COG4521@1|root,COG4521@2|Bacteria 2|Bacteria P taurine ABC transporter tauA - - ko:K15551 ko00920,ko02010,map00920,map02010 M00435 - - ko00000,ko00001,ko00002,ko02000 3.A.1.17.1,3.A.1.17.4 - - NMT1,NMT1_2,OpuAC k141_34630_6 1116375.VEJY3_24191 0.0 895.0 COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,1RNW9@1236|Gammaproteobacteria,1XUZX@135623|Vibrionales 1236|Gammaproteobacteria E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - 2.6.1.113,2.6.1.76,2.6.1.77 ko:K03851,ko:K12256,ko:K15785 ko00260,ko00330,ko00430,ko01100,map00260,map00330,map00430,map01100 - R05652,R06977,R08714 RC00006,RC00008,RC00062 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_3 k141_34630_7 1116375.VEJY3_24196 2.81e-138 403.0 COG1167@1|root,COG1167@2|Bacteria,1MVGT@1224|Proteobacteria,1RPFK@1236|Gammaproteobacteria,1XTBA@135623|Vibrionales 135623|Vibrionales K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs - - - ko:K00375 - - - - ko00000,ko03000 - - - Aminotran_1_2,GntR k141_26367_1 218284.CCDN010000002_gene1989 1.14e-171 489.0 COG0034@1|root,COG0034@2|Bacteria,1TPH3@1239|Firmicutes,4HAXU@91061|Bacilli,1ZCE0@1386|Bacillus 91061|Bacilli F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine purF - 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 - - iSB619.SA_RS05225 GATase_6,GATase_7,Pribosyltran k141_13273_1 218284.CCDN010000002_gene2471 6.47e-23 96.7 COG3935@1|root,COG3935@2|Bacteria,1V9YA@1239|Firmicutes,4HN3B@91061|Bacilli,1ZEMU@1386|Bacillus 91061|Bacilli L primosome component and related proteins - - - - - - - - - - - - DnaB_2 k141_36982_1 1294265.JCM21738_3243 3.12e-186 526.0 COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,4H9Y8@91061|Bacilli,1ZBUR@1386|Bacillus 91061|Bacilli L Participates in initiation and elongation during chromosome replication dnaB GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k141_18063_1 1238186.AOCN01000010_gene1508 9.26e-18 84.0 COG0161@1|root,COG0161@2|Bacteria,2GKF6@201174|Actinobacteria,4FK8X@85023|Microbacteriaceae 201174|Actinobacteria H Aminotransferase class-III - - - - - - - - - - - - Aminotran_3 k141_19161_1 10724.Q38150_BPSPP 8.65e-24 101.0 4QAX8@10239|Viruses,4QVB1@35237|dsDNA viruses no RNA stage,4QPHH@28883|Caudovirales,4QKTJ@10699|Siphoviridae 10699|Siphoviridae S calcium ion binding - - - - - - - - - - - - - k141_23915_1 1227454.C446_16215 7.98e-22 94.7 COG3247@1|root,arCOG10041@2157|Archaea,2XWIC@28890|Euryarchaeota,23V5B@183963|Halobacteria 183963|Halobacteria S Short repeat of unknown function (DUF308) - - - - - - - - - - - - DUF308 k141_14457_2 574375.BAGA_18895 3.79e-26 101.0 2CGUI@1|root,2ZG4Q@2|Bacteria,1W5X9@1239|Firmicutes,4I1AZ@91061|Bacilli,1ZNUP@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_27477_2 218284.CCDN010000001_gene1824 8.62e-197 565.0 COG0550@1|root,COG0551@1|root,COG0550@2|Bacteria,COG0551@2|Bacteria,1TPJD@1239|Firmicutes,4HAZV@91061|Bacilli,1ZBEG@1386|Bacillus 91061|Bacilli L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topB - 5.99.1.2 ko:K03169 - - - - ko00000,ko01000,ko03032 - - - Topoisom_bac,Toprim k141_33423_1 1492922.GY26_13355 2.07e-72 226.0 COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,1RSC6@1236|Gammaproteobacteria,1JBR7@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC k141_1314_1 441769.ABFU01000068_gene2020 4.57e-17 85.1 COG1948@1|root,COG4880@2|Bacteria,1TQK0@1239|Firmicutes,4H9YF@91061|Bacilli,1ZDVB@1386|Bacillus 91061|Bacilli L Beta propeller domain - - - - - - - - - - - - Beta_propel,Big_5,Cu_amine_oxidN1 k141_10823_1 218284.CCDN010000010_gene4332 2.21e-84 249.0 COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,4HH3B@91061|Bacilli,1ZG6R@1386|Bacillus 91061|Bacilli J Belongs to the universal ribosomal protein uS9 family rpsI GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02996 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S9 k141_10823_2 218284.CCDN010000010_gene4333 4.8e-102 295.0 COG0102@1|root,COG0102@2|Bacteria,1V3HX@1239|Firmicutes,4HG0I@91061|Bacilli,1ZFJA@1386|Bacillus 91061|Bacilli J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly rplM GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02871 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L13 k141_10823_3 218284.CCDN010000010_gene4334 2.56e-42 145.0 COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,4HCFI@91061|Bacilli,1ZCC7@1386|Bacillus 91061|Bacilli J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs truA GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 ko:K06173 - - - - ko00000,ko01000,ko03016 - - - PseudoU_synth_1 k141_31114_2 1279017.AQYJ01000019_gene1511 5.59e-58 184.0 COG4968@1|root,COG4968@2|Bacteria,1N6QE@1224|Proteobacteria,1SCBS@1236|Gammaproteobacteria,467AA@72275|Alteromonadaceae 1236|Gammaproteobacteria NU COG4968 Tfp pilus assembly protein PilE pilE - - ko:K02655 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - ComP_DUS,N_methyl k141_31114_3 1279017.AQYJ01000019_gene1512 7.8e-70 218.0 COG4970@1|root,COG4970@2|Bacteria,1QFYA@1224|Proteobacteria,1SDXQ@1236|Gammaproteobacteria,468F0@72275|Alteromonadaceae 1236|Gammaproteobacteria NU COG4970 Tfp pilus assembly protein FimT fimT - - ko:K08084 - - - - ko00000,ko02044 3.A.15.2 - - GspH,N_methyl k141_7309_1 1205908.AKXW01000069_gene3547 1.99e-44 155.0 2DDWT@1|root,2ZJMV@2|Bacteria,1NKC4@1224|Proteobacteria,1STHR@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_2578_1 218284.CCDN010000001_gene1593 2.13e-07 51.2 COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,4HA2S@91061|Bacilli,1ZAUS@1386|Bacillus 91061|Bacilli P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components dppB GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0022857,GO:0051179,GO:0051234,GO:0055085 - ko:K16200 ko02010,map02010 M00566 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.2 - iYO844.BSU12930 BPD_transp_1 k141_2578_2 796606.BMMGA3_08840 3.15e-80 245.0 COG2362@1|root,COG2362@2|Bacteria,1TSUZ@1239|Firmicutes,4HC5R@91061|Bacilli,1ZC41@1386|Bacillus 91061|Bacilli E D-aminopeptidase dppA - - ko:K16203 - - - - ko00000,ko01000,ko01002 3.A.1.5.2 - iYO844.BSU12920 Peptidase_M55 k141_29862_1 218284.CCDN010000001_gene1110 1.12e-148 420.0 COG0500@1|root,COG2226@2|Bacteria,1TQEA@1239|Firmicutes,4HAR9@91061|Bacilli,1ZB6U@1386|Bacillus 91061|Bacilli H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) menG GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.1.1.163,2.1.1.201 ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116,M00117 R04990,R04993,R06859,R08774,R09736 RC00003,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000 - - - Ubie_methyltran k141_14458_1 1453501.JELR01000002_gene1407 2.36e-118 347.0 COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,1RNIR@1236|Gammaproteobacteria,464PA@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG0332 3-oxoacyl- acyl-carrier-protein synthase III fabH - 2.3.1.207 ko:K16872 - - - - ko00000,ko01000 - - - ACP_syn_III,ACP_syn_III_C k141_33424_1 221109.22775914 1.21e-84 280.0 COG1404@1|root,COG1404@2|Bacteria,1TPH1@1239|Firmicutes,4HBQH@91061|Bacilli,23IZR@182709|Oceanobacillus 91061|Bacilli O PA domain prtS - 3.4.21.110,3.4.21.96 ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 - - - ko00000,ko00001,ko01000,ko01002,ko03110 - - - FIVAR,Gram_pos_anchor,Inhibitor_I9,PA,Peptidase_S8,SLH,YSIRK_signal,fn3_5 k141_241_1 1125863.JAFN01000001_gene34 8.3e-122 367.0 COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,42M0T@68525|delta/epsilon subdivisions,2WJ3C@28221|Deltaproteobacteria 28221|Deltaproteobacteria E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism glyA - 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 - - - SHMT k141_10824_1 218284.CCDN010000007_gene4006 7.38e-81 241.0 2E48W@1|root,32Z4Q@2|Bacteria,1VF41@1239|Firmicutes,4HPBF@91061|Bacilli,1ZGKF@1386|Bacillus 91061|Bacilli - - cotB - - ko:K06325 - - - - ko00000 - - - - k141_10824_2 218284.CCDN010000007_gene4005 1.01e-26 103.0 2C35D@1|root,34CE1@2|Bacteria,1W2J3@1239|Firmicutes,4I0HR@91061|Bacilli,1ZFHP@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_7310_1 218284.CCDN010000001_gene1807 2.52e-101 311.0 COG0323@1|root,COG0323@2|Bacteria,1TPGK@1239|Firmicutes,4HB34@91061|Bacilli,1ZB9X@1386|Bacillus 91061|Bacilli L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex mutL GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032300,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1990391 - ko:K03572 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - DNA_mis_repair,HATPase_c_3,MutL_C k141_15663_1 1453501.JELR01000001_gene2993 4.81e-59 184.0 2B2JB@1|root,32XJW@2|Bacteria,1MZQH@1224|Proteobacteria,1SB5E@1236|Gammaproteobacteria,46DN6@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF2750) - - - - - - - - - - - - DUF2750 k141_26368_2 1279017.AQYJ01000029_gene3712 2.62e-125 360.0 COG0693@1|root,COG0693@2|Bacteria,1MVTT@1224|Proteobacteria,1RPVK@1236|Gammaproteobacteria,464CB@72275|Alteromonadaceae 1236|Gammaproteobacteria S DJ-1/PfpI family - - - - - - - - - - - - DJ-1_PfpI k141_26368_3 349966.DJ58_4078 1.04e-30 115.0 COG2356@1|root,COG2356@2|Bacteria,1MXQM@1224|Proteobacteria,1RPX9@1236|Gammaproteobacteria,41EN2@629|Yersinia 1236|Gammaproteobacteria L Endonuclease I endA GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005576,GO:0005623,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0016888,GO:0016893,GO:0019439,GO:0034641,GO:0034655,GO:0042597,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 3.1.21.1 ko:K01150 - - - - ko00000,ko01000 - - - Endonuclease_1 k141_18065_1 1116375.VEJY3_19286 2.72e-63 207.0 COG4670@1|root,COG4670@2|Bacteria,1MUJW@1224|Proteobacteria,1RP80@1236|Gammaproteobacteria,1Y251@135623|Vibrionales 135623|Vibrionales I CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons - - 2.8.3.1 ko:K01026 ko00620,ko00640,ko00643,ko01100,ko01120,map00620,map00640,map00643,map01100,map01120 - R00928,R01449,R05508 RC00012,RC00014,RC00137 ko00000,ko00001,ko01000 - - - CoA_trans k141_18065_2 1116375.VEJY3_19281 9.51e-68 213.0 COG0583@1|root,COG0583@2|Bacteria,1R8Z6@1224|Proteobacteria,1S1YG@1236|Gammaproteobacteria,1XVMQ@135623|Vibrionales 135623|Vibrionales K COG0583 Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_23917_1 1294265.JCM21738_2985 2.88e-69 214.0 COG0596@1|root,COG0596@2|Bacteria,1TS4C@1239|Firmicutes,4HB6G@91061|Bacilli,1ZAU9@1386|Bacillus 91061|Bacilli S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) menH GO:0003674,GO:0003824,GO:0016787 4.2.99.20 ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R08166 RC02148,RC02475 ko00000,ko00001,ko00002,ko01000 - - - Abhydrolase_1 k141_23917_2 441769.ABFU01000052_gene4146 1.33e-39 138.0 COG0447@1|root,COG0447@2|Bacteria,1UHNU@1239|Firmicutes,4HAD0@91061|Bacilli,1ZB3B@1386|Bacillus 91061|Bacilli H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) menB GO:0003674,GO:0003824,GO:0005488,GO:0006732,GO:0008150,GO:0008152,GO:0008935,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0042180,GO:0042181,GO:0043167,GO:0043168,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:0071890,GO:1901576,GO:1901661,GO:1901663 4.1.3.36 ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R07263 RC01923 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 k141_35795_2 218284.CCDN010000002_gene2210 1.43e-104 303.0 COG1607@1|root,COG1607@2|Bacteria,1V3S2@1239|Firmicutes,4HJ0Z@91061|Bacilli,1ZGQ9@1386|Bacillus 91061|Bacilli I Acyl-CoA hydrolase ykhA - - - - - - - - - - - 4HBT k141_14459_1 583355.Caka_1508 1.24e-09 59.3 COG0668@1|root,COG0668@2|Bacteria 2|Bacteria M transmembrane transport VP2168 - - ko:K03442 - - - - ko00000,ko02000 1.A.23.2 - - MS_channel k141_28749_1 1120970.AUBZ01000003_gene162 1.66e-178 511.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,4650W@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains prsR - - ko:K02481 - - - - ko00000,ko02022 - - - HTH_8,Response_reg,Sigma54_activat k141_8520_1 218284.CCDN010000001_gene622 1.22e-85 262.0 2DTMA@1|root,33KWF@2|Bacteria,1VQ6W@1239|Firmicutes,4HSQC@91061|Bacilli,1ZCP7@1386|Bacillus 91061|Bacilli - - spoIIB - - ko:K06380 - - - - ko00000 - - - SPOR k141_10825_1 42565.FP66_05870 1.01e-72 228.0 COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,1RNID@1236|Gammaproteobacteria,1XI3Q@135619|Oceanospirillales 135619|Oceanospirillales M Catalyzes the transfer of a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge - - 2.1.1.79 ko:K00574 - - - - ko00000,ko01000 - - - CMAS k141_26369_1 1131730.BAVI_12644 1.03e-21 93.6 COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,4HBDP@91061|Bacilli,1ZAYG@1386|Bacillus 91061|Bacilli S protein conserved in bacteria - - - - - - - - - - - - DegV k141_26369_2 641526.ADIWIN_2761 4.89e-10 59.7 COG1418@1|root,COG1418@2|Bacteria,4NEZY@976|Bacteroidetes,1HX55@117743|Flavobacteriia 976|Bacteroidetes S HD superfamily hydrolase - - - ko:K06950 - - - - ko00000 - - - HD k141_36984_2 1340434.AXVA01000005_gene4763 4.26e-22 85.9 2DKK1@1|root,309RW@2|Bacteria,1U5JZ@1239|Firmicutes,4IFAR@91061|Bacilli,1ZK2R@1386|Bacillus 91061|Bacilli S YqzL-like protein - - - - - - - - - - - - YqzL k141_36984_3 1294265.JCM21738_3312 4.59e-188 524.0 COG1159@1|root,COG1159@2|Bacteria,1TP3R@1239|Firmicutes,4H9WF@91061|Bacilli,1ZCSH@1386|Bacillus 91061|Bacilli S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism era GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113 - ko:K03595 - - - - ko00000,ko03009,ko03029 - - - KH_2,MMR_HSR1 k141_20332_1 218284.CCDN010000001_gene1335 4.43e-70 218.0 COG2105@1|root,COG3703@1|root,COG2105@2|Bacteria,COG3703@2|Bacteria,1V4XC@1239|Firmicutes,4HH0F@91061|Bacilli,1ZJQH@1386|Bacillus 91061|Bacilli P Gamma-glutamyl cyclotransferase, AIG2-like ykqA - - - - - - - - - - - AIG2_2,GGACT k141_20332_2 218284.CCDN010000001_gene1336 0.000812 40.8 COG0586@1|root,COG0586@2|Bacteria,1V31C@1239|Firmicutes,4HGNQ@91061|Bacilli,1ZICE@1386|Bacillus 91061|Bacilli S SNARE associated Golgi protein - - - ko:K03975 - - - - ko00000 - - - SNARE_assoc k141_14460_1 1423321.AS29_09645 1.36e-88 275.0 COG4146@1|root,COG4146@2|Bacteria,1UHPR@1239|Firmicutes,4HDFI@91061|Bacilli,1ZDJB@1386|Bacillus 91061|Bacilli S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - ko:K03307 - - - - ko00000 2.A.21 - - SSF k141_6188_1 1294265.JCM21738_2934 2.34e-69 211.0 COG4980@1|root,COG4980@2|Bacteria,1VAKP@1239|Firmicutes,4HKD5@91061|Bacilli,1ZJ3D@1386|Bacillus 91061|Bacilli S YtxH-like protein yhaH - - - - - - - - - - - YtxH k141_27480_1 1453501.JELR01000001_gene2037 3.29e-58 193.0 COG3746@1|root,COG3746@2|Bacteria,1RG6T@1224|Proteobacteria,1S412@1236|Gammaproteobacteria,468U6@72275|Alteromonadaceae 1236|Gammaproteobacteria P Phosphate-selective porin O and P oprO - - ko:K07221 - - - - ko00000,ko02000 1.B.5.1 - - Porin_O_P k141_35796_1 1532557.JL37_16615 8.82e-113 347.0 COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,2VIB1@28216|Betaproteobacteria,3T5P5@506|Alcaligenaceae 28216|Betaproteobacteria C Catalytic subunit of the nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC. Essential function for nitrate assimilation and may have a role in anaerobic metabolism napA - - ko:K02567 ko00910,ko01120,map00910,map01120 M00529,M00530 R00798,R01106 RC02812 ko00000,ko00001,ko00002,ko01000 - - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding k141_1317_1 218284.CCDN010000002_gene2203 4.02e-14 71.2 COG3764@1|root,COG3764@2|Bacteria,1V79B@1239|Firmicutes,4HJ8C@91061|Bacilli,1ZHDM@1386|Bacillus 91061|Bacilli M Sortase family - - - - - - - - - - - - Sortase k141_1317_2 218284.CCDN010000002_gene2204 5.15e-41 146.0 28HWT@1|root,2Z82P@2|Bacteria,1TSBJ@1239|Firmicutes,4HCMR@91061|Bacilli,1ZB7P@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - Xpo1 k141_33426_1 558169.AGAV01000003_gene2941 1.85e-23 95.5 COG1595@1|root,COG1595@2|Bacteria,1V4B8@1239|Firmicutes,4HHCY@91061|Bacilli 91061|Bacilli K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4,Sigma70_r4_2 k141_33426_2 1385514.N782_01135 6.51e-21 90.1 COG5662@1|root,COG5662@2|Bacteria,1V446@1239|Firmicutes,4HHFJ@91061|Bacilli,2YABG@289201|Pontibacillus 91061|Bacilli K Anti-sigma-K factor rskA - - - - - - - - - - - - RskA,zf-HC2 k141_12052_1 517418.Ctha_0880 1.38e-78 253.0 COG1660@1|root,COG3178@1|root,COG1660@2|Bacteria,COG3178@2|Bacteria,1FEBN@1090|Chlorobi 1090|Chlorobi S PFAM aminoglycoside phosphotransferase - - 2.7.1.221 ko:K07102 ko00520,ko01100,map00520,map01100 - R08968,R11024 RC00002,RC00078 ko00000,ko00001,ko01000 - - - APH k141_12052_2 351607.Acel_1231 7.83e-19 93.2 COG1109@1|root,COG1208@1|root,COG1109@2|Bacteria,COG1208@2|Bacteria,2GKTE@201174|Actinobacteria,4ERX2@85013|Frankiales 201174|Actinobacteria M alpha beta alpha domain I - - 2.7.7.13,5.4.2.8 ko:K16881 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 M00114,M00362 R00885,R01818 RC00002,RC00408 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transferase,PGM_PMM_I,PGM_PMM_II,PGM_PMM_III k141_12052_3 1173020.Cha6605_6158 2.73e-37 137.0 COG0454@1|root,COG1846@1|root,COG0456@2|Bacteria,COG1846@2|Bacteria 2|Bacteria K DNA-binding transcription factor activity - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_7,MarR,MarR_2 k141_18066_1 218284.CCDN010000001_gene731 8.78e-179 504.0 COG0635@1|root,COG0635@2|Bacteria,1TPES@1239|Firmicutes,4HA60@91061|Bacilli,1ZC7V@1386|Bacillus 91061|Bacilli H Involved in the biosynthesis of porphyrin-containing compound hemN GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - - - - - - - - - - HemN_C,Radical_SAM k141_6189_1 218284.CCDN010000002_gene2729 2.92e-30 121.0 COG1595@1|root,COG1595@2|Bacteria,1U9I0@1239|Firmicutes,4IJNF@91061|Bacilli,1ZC9D@1386|Bacillus 91061|Bacilli K Domain of unknown function (DUF4179) - - - - - - - - - - - - DUF4179,Sigma70_r4,Sigma70_r4_2,zf-HC2 k141_31116_1 1279017.AQYJ01000026_gene275 3.92e-180 533.0 COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,464QT@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0642 Signal transduction histidine kinase barA GO:0000155,GO:0000160,GO:0000302,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009636,GO:0009927,GO:0009987,GO:0010033,GO:0010035,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0035556,GO:0036211,GO:0042221,GO:0042493,GO:0042542,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046677,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0070887,GO:0071310,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901700 2.7.13.3 ko:K07678 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 M00475 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - DUF2222,HAMP,HATPase_c,HisKA,Hpt,Response_reg k141_26370_1 218284.CCDN010000005_gene3246 2.67e-61 201.0 COG0534@1|root,COG0534@2|Bacteria,1TQMT@1239|Firmicutes,4H9Y2@91061|Bacilli,1ZBQK@1386|Bacillus 91061|Bacilli V Mate efflux family protein yisQ - - - - - - - - - - - MatE k141_10848_2 1415778.JQMM01000001_gene1966 1.09e-05 48.1 2BHRH@1|root,32BUY@2|Bacteria,1MZ2C@1224|Proteobacteria,1SARJ@1236|Gammaproteobacteria,1JAJS@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_6219_2 218284.CCDN010000001_gene1134 4.33e-130 373.0 COG2120@1|root,COG2120@2|Bacteria,1TV10@1239|Firmicutes,4HFJQ@91061|Bacilli,1ZAZI@1386|Bacillus 91061|Bacilli S proteins, LmbE homologs ypjG - - ko:K01463 - - - - ko00000,ko01000 - - - PIG-L k141_6219_3 218284.CCDN010000001_gene1133 2.63e-83 247.0 COG1803@1|root,COG1803@2|Bacteria,1V3KQ@1239|Firmicutes,4HH64@91061|Bacilli,1ZGAF@1386|Bacillus 91061|Bacilli G methylglyoxal synthase mgsA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0008150,GO:0008152,GO:0008929,GO:0009058,GO:0009438,GO:0009987,GO:0016829,GO:0016835,GO:0016838,GO:0019242,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0071704,GO:1901576 4.2.3.3 ko:K01734 ko00640,ko01120,map00640,map01120 - R01016 RC00424 ko00000,ko00001,ko01000 - - - MGS k141_2598_1 350054.Mflv_1318 1.35e-06 52.4 COG4301@1|root,COG4301@2|Bacteria,2GJAX@201174|Actinobacteria,23577@1762|Mycobacteriaceae 201174|Actinobacteria S Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine egtD GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006547,GO:0006548,GO:0006575,GO:0006577,GO:0006578,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008213,GO:0008276,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016020,GO:0016053,GO:0016054,GO:0016740,GO:0016741,GO:0019439,GO:0019538,GO:0019752,GO:0032259,GO:0034641,GO:0036211,GO:0042398,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044270,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044283,GO:0044464,GO:0046394,GO:0046395,GO:0046483,GO:0046700,GO:0052698,GO:0052699,GO:0052701,GO:0052703,GO:0052704,GO:0052707,GO:0052708,GO:0052709,GO:0052803,GO:0052805,GO:0071704,GO:0071944,GO:0097164,GO:0140096,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.1.1.44 ko:K18911 ko00340,map00340 - R01169 RC00003,RC02308 ko00000,ko00001,ko01000 - - - Methyltransf_33 k141_37178_6 1116375.VEJY3_19491 9.08e-204 565.0 COG0583@1|root,COG0583@2|Bacteria,1PJYV@1224|Proteobacteria,1RSA1@1236|Gammaproteobacteria,1XVV9@135623|Vibrionales 135623|Vibrionales K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_37178_7 1116375.VEJY3_19496 0.0 1116.0 COG0277@1|root,COG0277@2|Bacteria,1MVG7@1224|Proteobacteria,1RN5V@1236|Gammaproteobacteria,1XUQW@135623|Vibrionales 135623|Vibrionales C Belongs to the quinone-dependent D-lactate dehydrogenase family dld - 1.1.5.12 ko:K03777 ko00620,ko01120,map00620,map01120 - R00704,R11591 RC00044 ko00000,ko00001,ko01000 - - - FAD_binding_4,Lact-deh-memb k141_37178_8 1219076.N646_4378 3.53e-52 166.0 COG4541@1|root,COG4541@2|Bacteria,1NDCP@1224|Proteobacteria,1SF44@1236|Gammaproteobacteria,1XYIS@135623|Vibrionales 135623|Vibrionales S Branched-chain amino acid transport protein (AzlD) - - - - - - - - - - - - AzlD k141_510_1 323850.Shew_2867 1.73e-108 342.0 COG0439@1|root,COG4799@1|root,COG0439@2|Bacteria,COG4799@2|Bacteria,1MU4H@1224|Proteobacteria,1RMNB@1236|Gammaproteobacteria,2QAWT@267890|Shewanellaceae 1236|Gammaproteobacteria I Carbamoyl-phosphate synthetase large chain domain protein - - - - - - - - - - - - Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 k141_33712_1 935836.JAEL01000100_gene4230 1.15e-134 387.0 COG0226@1|root,COG0226@2|Bacteria,1TQ5X@1239|Firmicutes,4HBEB@91061|Bacilli,1ZB22@1386|Bacillus 91061|Bacilli P Phosphate pstS GO:0003674,GO:0005488,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015698,GO:0042301,GO:0043167,GO:0043168,GO:0051179,GO:0051234 - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - PBP_like_2 k141_8779_1 477974.Daud_1050 6.26e-76 255.0 COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia,2605R@186807|Peptococcaceae 186801|Clostridia L DNA polymerase III alpha subunit dnaE - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon k141_12405_1 1116375.VEJY3_00930 6.65e-139 398.0 COG0438@1|root,COG0438@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups - - - - - - - - - - - - Glyco_trans_1_4,Glycos_transf_1 k141_12405_2 1116375.VEJY3_00925 2.78e-253 696.0 COG0562@1|root,COG0562@2|Bacteria,1MV4H@1224|Proteobacteria,1RPMY@1236|Gammaproteobacteria,1Y0US@135623|Vibrionales 135623|Vibrionales M UDP-galactopyranose mutase - - 5.4.99.9 ko:K01854 ko00052,ko00520,map00052,map00520 - R00505,R09009 RC00317,RC02396 ko00000,ko00001,ko01000 - - - GLF,NAD_binding_8 k141_12405_3 1051646.VITU9109_13022 6.37e-102 298.0 COG1898@1|root,COG1898@2|Bacteria,1R9YD@1224|Proteobacteria,1S245@1236|Gammaproteobacteria,1XSKQ@135623|Vibrionales 135623|Vibrionales G Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose rfbC - 5.1.3.13 ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R06514 RC01531 ko00000,ko00001,ko00002,ko01000 - - - dTDP_sugar_isom k141_12405_4 1095743.HMPREF1054_0457 1.33e-60 197.0 COG1091@1|root,COG1091@2|Bacteria,1MUXM@1224|Proteobacteria,1RSNR@1236|Gammaproteobacteria,1Y6XW@135625|Pasteurellales 135625|Pasteurellales M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose - - 1.1.1.133 ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777 RC00182 ko00000,ko00001,ko00002,ko01000 - - - RmlD_sub_bind k141_26744_1 1116375.VEJY3_14110 5.1e-288 785.0 COG0624@1|root,COG0624@2|Bacteria,1MVBR@1224|Proteobacteria,1RNDG@1236|Gammaproteobacteria,1XVA2@135623|Vibrionales 135623|Vibrionales E Belongs to the peptidase M20A family. ArgE subfamily argE GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008777,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.1.16 ko:K01438 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R00669,R09107 RC00064,RC00300 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20 k141_26744_2 1116375.VEJY3_14105 2.15e-235 648.0 COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,1RNMX@1236|Gammaproteobacteria,1XSZ0@135623|Vibrionales 135623|Vibrionales E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde argC GO:0003674,GO:0003824,GO:0003942,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.38 ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R03443 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC k141_26744_3 1116375.VEJY3_14100 3.83e-91 272.0 COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,1RNKK@1236|Gammaproteobacteria,1XSF2@135623|Vibrionales 135623|Vibrionales F Belongs to the acetylglutamate kinase family. ArgB subfamily argB GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R02649 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase k141_25388_1 1453501.JELR01000001_gene2245 3.94e-175 505.0 COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,1RQ4N@1236|Gammaproteobacteria,4648E@72275|Alteromonadaceae 1236|Gammaproteobacteria Q multicopper oxidases pcoA - - - - - - - - - - - CopB,Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3 k141_17040_1 1307436.PBF_16094 5.42e-17 78.2 29X3J@1|root,32W55@2|Bacteria,1VAGX@1239|Firmicutes,4HN0C@91061|Bacilli,1ZIZD@1386|Bacillus 91061|Bacilli S Spore coat protein Z - - - - - - - - - - - - Spore-coat_CotZ k141_8780_1 218284.CCDN010000001_gene1860 2.17e-76 233.0 28HGR@1|root,2Z7SI@2|Bacteria,1TRXV@1239|Firmicutes,4HA2I@91061|Bacilli,1ZAU1@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3388) ymfK - - - - - - - - - - - DUF3388 k141_37179_1 1294265.JCM21738_3388 4.52e-191 558.0 COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,4HAFP@91061|Bacilli,1ZBJ3@1386|Bacillus 91061|Bacilli V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran k141_18289_1 935836.JAEL01000030_gene3419 1.19e-93 288.0 COG1174@1|root,COG1732@1|root,COG1174@2|Bacteria,COG1732@2|Bacteria,1TQ7D@1239|Firmicutes,4HBDR@91061|Bacilli,1ZBSA@1386|Bacillus 91061|Bacilli EM COG1174 ABC-type proline glycine betaine transport systems, permease component proWX - - ko:K05845,ko:K05846 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - BPD_transp_1,OpuAC k141_20551_2 218284.CCDN010000001_gene34 1.44e-124 371.0 COG1461@1|root,COG1461@2|Bacteria,1TQMX@1239|Firmicutes,4HBSE@91061|Bacilli,1ZBRP@1386|Bacillus 91061|Bacilli S kinase related to dihydroxyacetone kinase yloV - - ko:K07030 - - - - ko00000 - - - Dak1_2,Dak2 k141_19420_2 1116375.VEJY3_04825 3.52e-165 468.0 COG2207@1|root,COG2207@2|Bacteria,1R5XR@1224|Proteobacteria,1S6MB@1236|Gammaproteobacteria,1XUBW@135623|Vibrionales 135623|Vibrionales K COG2207 AraC-type DNA-binding domain-containing proteins - - - - - - - - - - - - Arabinose_bd,HTH_18 k141_33714_2 1294265.JCM21738_5112 2.58e-32 118.0 COG0647@1|root,COG0647@2|Bacteria,1TQGM@1239|Firmicutes,4HA3R@91061|Bacilli,1ZB73@1386|Bacillus 91061|Bacilli G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro nagD - 3.1.3.41 ko:K01101 ko00627,ko01120,map00627,map01120 - R03024 RC00151 ko00000,ko00001,ko01000 - - - Hydrolase_6,Hydrolase_like k141_512_1 42565.FP66_01100 5.5e-163 463.0 COG3007@1|root,COG3007@2|Bacteria,1MWCQ@1224|Proteobacteria,1RPPP@1236|Gammaproteobacteria,1XHH9@135619|Oceanospirillales 135619|Oceanospirillales I Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP) fabV - 1.3.1.44,1.3.1.9 ko:K00209 ko00061,ko00650,ko01100,ko01120,ko01200,ko01212,map00061,map00650,map01100,map01120,map01200,map01212 M00083 R01171,R04429,R04724,R04955,R04958,R04961,R04966,R04969 RC00052,RC00076 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Eno-Rase_FAD_bd,Eno-Rase_NADH_b,Enoyl_reductase k141_21801_1 1538644.KO02_01420 3.87e-58 197.0 COG2159@1|root,COG2159@2|Bacteria 2|Bacteria E amidohydrolase - - 4.1.1.46 ko:K07045,ko:K14333 ko00362,ko00627,ko01120,map00362,map00627,map01120 - R00821 RC00390 ko00000,ko00001,ko01000 - - - Amidohydro_2,DDE_Tnp_1_4 k141_37180_1 1294265.JCM21738_1433 1.26e-139 399.0 COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,4H9YB@91061|Bacilli,1ZBA4@1386|Bacillus 91061|Bacilli E Belongs to the ABC transporter superfamily ykfD - - ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY k141_25391_1 1042377.AFPJ01000036_gene1150 6.05e-43 152.0 COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,1RPAB@1236|Gammaproteobacteria,469E2@72275|Alteromonadaceae 1236|Gammaproteobacteria C Glycolate oxidase iron-sulfur subunit glcF - - ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001 - - - CCG,Fer4_7,Fer4_8 k141_20552_1 1403313.AXBR01000002_gene4394 4.84e-79 250.0 COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,4H9VK@91061|Bacilli,1ZB07@1386|Bacillus 91061|Bacilli G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system - - 3.6.3.17 ko:K02056 - M00221 - - ko00000,ko00002,ko01000,ko02000 3.A.1.2 - - ABC_tran k141_15843_1 218284.CCDN010000006_gene3560 4.54e-93 283.0 COG0477@1|root,COG2814@2|Bacteria,1TSS7@1239|Firmicutes,4HC6A@91061|Bacilli,1ZBCF@1386|Bacillus 91061|Bacilli EGP Transmembrane secretion effector - - - - - - - - - - - - MFS_1 k141_24138_2 1116375.VEJY3_23316 2.09e-297 823.0 COG0457@1|root,COG0457@2|Bacteria,1MXK4@1224|Proteobacteria,1RNFM@1236|Gammaproteobacteria,1XU0S@135623|Vibrionales 135623|Vibrionales S Oxygen tolerance - - - - - - - - - - - - BatD k141_24138_3 1116375.VEJY3_23321 3.63e-101 297.0 COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,1RNUF@1236|Gammaproteobacteria,1XT9N@135623|Vibrionales 135623|Vibrionales P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system pstB2 GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015114,GO:0015318,GO:0015399,GO:0015405,GO:0015415,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0035435,GO:0042623,GO:0042626,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0098660,GO:0098661,GO:0099133 3.6.3.27 ko:K02036 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 - - ABC_tran k141_14628_1 1042377.AFPJ01000043_gene878 4.45e-65 201.0 COG2947@1|root,COG2947@2|Bacteria,1RHRU@1224|Proteobacteria,1S68X@1236|Gammaproteobacteria,467AM@72275|Alteromonadaceae 1236|Gammaproteobacteria S EVE domain - - - - - - - - - - - - EVE k141_8782_1 1453501.JELR01000005_gene1567 2.23e-156 451.0 COG1012@1|root,COG1012@2|Bacteria,1MVGW@1224|Proteobacteria,1RN53@1236|Gammaproteobacteria,4656Y@72275|Alteromonadaceae 1236|Gammaproteobacteria C belongs to the aldehyde dehydrogenase family calB - 1.2.1.68 ko:K00154 - - - - ko00000,ko01000 - - - Aldedh k141_24139_1 42565.FP66_10750 1.16e-116 353.0 COG2176@1|root,COG2176@2|Bacteria,1QUVW@1224|Proteobacteria,1RV0N@1236|Gammaproteobacteria,1XN61@135619|Oceanospirillales 135619|Oceanospirillales L DNA polymerase III - - 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - PAS_4,RNase_T k141_37181_1 218284.CCDN010000001_gene796 4.49e-95 300.0 COG0297@1|root,COG0297@2|Bacteria,1UHYC@1239|Firmicutes,4ISUZ@91061|Bacilli,1ZD41@1386|Bacillus 91061|Bacilli G Starch synthase catalytic domain - - - - - - - - - - - - Glyco_hydro_57,Glyco_transf_4,Glycos_transf_1 k141_20553_1 1042377.AFPJ01000054_gene1695 5.76e-05 45.4 2C5U9@1|root,2Z9NJ@2|Bacteria,1R6D0@1224|Proteobacteria,1SAQZ@1236|Gammaproteobacteria,46861@72275|Alteromonadaceae 1236|Gammaproteobacteria S Bacterial protein of unknown function (Gcw_chp) - - - - - - - - - - - - Gcw_chp k141_12410_1 1453501.JELR01000001_gene2398 2.57e-83 248.0 COG2356@1|root,COG2356@2|Bacteria,1RI3H@1224|Proteobacteria,1S6A9@1236|Gammaproteobacteria,4681D@72275|Alteromonadaceae 1236|Gammaproteobacteria L Protein of unknown function (DUF1524) - - - - - - - - - - - - DUF1524 k141_8783_2 218284.CCDN010000001_gene1948 2.12e-94 281.0 COG0345@1|root,COG0345@2|Bacteria,1TP1E@1239|Firmicutes,4H9RV@91061|Bacilli,1ZCWZ@1386|Bacillus 91061|Bacilli E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline proC - 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 - - - F420_oxidored,P5CR_dimer k141_21802_1 406124.ACPC01000022_gene4251 4.17e-84 250.0 arCOG10217@1|root,301DU@2|Bacteria,1V1QT@1239|Firmicutes,4HG9A@91061|Bacilli,1ZGHV@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF4385) - - - - - - - - - - - - DUF4385 k141_18293_2 1042377.AFPJ01000022_gene1298 1.15e-80 243.0 COG0566@1|root,COG0566@2|Bacteria,1MWBE@1224|Proteobacteria,1RMPR@1236|Gammaproteobacteria,466RK@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA trmH GO:0001510,GO:0002128,GO:0002938,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008175,GO:0008757,GO:0009020,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0106050,GO:0140098,GO:0140101,GO:1901360 2.1.1.34 ko:K00556 - - - - ko00000,ko01000,ko03016 - - - SpoU_methylas_C,SpoU_methylase k141_25393_2 218284.CCDN010000005_gene3430 1.42e-91 274.0 COG3584@1|root,COG3584@2|Bacteria,1UYMN@1239|Firmicutes,4HIVQ@91061|Bacilli,1ZDD1@1386|Bacillus 91061|Bacilli S protein conserved in bacteria yuiC - - - - - - - - - - - 3D k141_11110_1 1294265.JCM21738_3954 6.64e-107 318.0 COG0860@1|root,COG0860@2|Bacteria,1TSFS@1239|Firmicutes,4HACZ@91061|Bacilli,1ZAV0@1386|Bacillus 91061|Bacilli M stage II sporulation protein P spoIIP - - ko:K06385 - - - - ko00000 - - - SpoIIP k141_12411_1 935837.JAEK01000005_gene4499 1.68e-69 211.0 COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,4HIK3@91061|Bacilli,1ZGDK@1386|Bacillus 91061|Bacilli J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site rplS GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02884 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L19 k141_31289_1 754477.Q7C_1362 3.65e-129 374.0 COG0491@1|root,COG0491@2|Bacteria,1N0UK@1224|Proteobacteria,1S9V4@1236|Gammaproteobacteria,4634Y@72273|Thiotrichales 72273|Thiotrichales S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B k141_31289_2 317619.ANKN01000218_gene1775 1.38e-23 98.2 COG1075@1|root,COG1075@2|Bacteria,1GD6D@1117|Cyanobacteria,1MME0@1212|Prochloraceae 1117|Cyanobacteria S Alternative locus ID - - 3.1.1.3 ko:K01046 ko00561,ko01100,map00561,map01100 M00098 R02250,R02687 RC00020,RC00037,RC00041,RC00094 ko00000,ko00001,ko00002,ko01000 - - - Abhydrolase_1,DUF676 k141_8784_1 240302.BN982_03149 2.61e-33 131.0 COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,4HA09@91061|Bacilli 91061|Bacilli K Transcriptional lytR - - - - - - - - - - - LytR_cpsA_psr k141_37183_1 1033734.CAET01000054_gene1432 4.23e-115 341.0 COG1524@1|root,COG1524@2|Bacteria,1TRZ7@1239|Firmicutes,4HAY5@91061|Bacilli,1ZD4Z@1386|Bacillus 91061|Bacilli S type I phosphodiesterase nucleotide pyrophosphatase npp - - - - - - - - - - - Phosphodiest k141_6449_1 1121878.AUGL01000007_gene1127 8.3e-33 129.0 COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,1RMYC@1236|Gammaproteobacteria 1236|Gammaproteobacteria P ATPase, P-type (transporting), HAD superfamily, subfamily IC - - - - - - - - - - - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase k141_6449_2 314345.SPV1_08486 2.06e-226 654.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria 1224|Proteobacteria G Belongs to the PEP-utilizing enzyme family ppsA - 2.7.9.2 ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 M00173,M00374 R00199 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - PEP-utilizers,PEP-utilizers_C,PPDK_N k141_26750_1 866895.HBHAL_2664 7.16e-51 167.0 COG4359@1|root,COG4359@2|Bacteria,1V1V0@1239|Firmicutes,4HC1U@91061|Bacilli 91061|Bacilli E 2,3-diketo-5-methylthio-1-phosphopentane phosphatase - - - - - - - - - - - - HAD,Put_Phosphatase k141_26750_2 66692.ABC0230 4.41e-08 53.1 28PM4@1|root,2ZCA8@2|Bacteria,1V1PA@1239|Firmicutes,4HFNN@91061|Bacilli,1ZG8T@1386|Bacillus 91061|Bacilli S YtkA-like - - - - - - - - - - - - YtkA k141_515_1 997296.PB1_01025 1.3e-20 89.7 COG1377@1|root,COG1377@2|Bacteria,1TPRP@1239|Firmicutes,4HB7Y@91061|Bacilli,1ZBSH@1386|Bacillus 91061|Bacilli N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin flhB - - ko:K02401 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - Bac_export_2 k141_515_2 1294265.JCM21738_319 1.78e-65 206.0 COG1684@1|root,COG1684@2|Bacteria,1TRB2@1239|Firmicutes,4HA2E@91061|Bacilli,1ZBJF@1386|Bacillus 91061|Bacilli N Flagellar biosynthetic protein FliR fliR - - ko:K02421 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - Bac_export_1 k141_24141_1 218284.CCDN010000001_gene727 1.93e-136 395.0 COG0680@1|root,COG0680@2|Bacteria,1TPFY@1239|Firmicutes,4HAGH@91061|Bacilli,1ZC4A@1386|Bacillus 91061|Bacilli C Initiates the rapid degradation of small, acid-soluble proteins during spore germination gpr GO:0000003,GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019954,GO:0030436,GO:0032502,GO:0043170,GO:0043934,GO:0044238,GO:0071704,GO:0140096,GO:1901564 3.4.24.78 ko:K06012 - - - - ko00000,ko01000,ko01002 - - - Peptidase_A25 k141_20555_1 1042377.AFPJ01000057_gene6 3.16e-66 207.0 COG3019@1|root,COG3019@2|Bacteria,1MZ9V@1224|Proteobacteria,1S9CQ@1236|Gammaproteobacteria,46779@72275|Alteromonadaceae 1236|Gammaproteobacteria S metal-binding protein copG - - - - - - - - - - - DUF411 k141_14629_1 1279017.AQYJ01000023_gene3085 6.36e-193 550.0 COG0471@1|root,COG0569@1|root,COG0471@2|Bacteria,COG0569@2|Bacteria,1MU0K@1224|Proteobacteria,1RMI1@1236|Gammaproteobacteria,464A6@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0471 Di- and tricarboxylate transporters - - - - - - - - - - - - CitMHS,TrkA_C k141_21816_2 42565.FP66_01285 2.9e-74 224.0 COG1959@1|root,COG1959@2|Bacteria,1RDA4@1224|Proteobacteria,1S3RW@1236|Gammaproteobacteria,1XJI3@135619|Oceanospirillales 135619|Oceanospirillales K Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins iscR - - ko:K13643 - - - - ko00000,ko03000 - - - Rrf2 k141_27618_2 1453501.JELR01000002_gene100 5.64e-30 120.0 COG1251@1|root,COG1251@2|Bacteria,1MW58@1224|Proteobacteria,1RNGY@1236|Gammaproteobacteria,465T8@72275|Alteromonadaceae 1236|Gammaproteobacteria C Pyridine nucleotide-disulphide oxidoreductase - - 1.7.1.15 ko:K00362 ko00910,ko01120,map00910,map01120 M00530 R00787 RC00176 ko00000,ko00001,ko00002,ko01000 - - - Fer2_BFD,Pyr_redox_2 k141_12440_1 218284.CCDN010000001_gene585 1.22e-154 441.0 COG5401@1|root,COG5401@2|Bacteria,1TPQD@1239|Firmicutes,4HB1S@91061|Bacilli,1ZBZJ@1386|Bacillus 91061|Bacilli S COG5401 Spore germination protein gerM - - ko:K06298 - - - - ko00000 - - - Germane k141_1544_1 1279017.AQYJ01000022_gene2702 2.29e-69 218.0 COG0589@1|root,COG0589@2|Bacteria,1PAFP@1224|Proteobacteria,1RSCS@1236|Gammaproteobacteria,465CE@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - - - - - - - - - - Usp k141_20572_1 1294265.JCM21738_3837 7.78e-60 185.0 COG4392@1|root,COG4392@2|Bacteria,1VCJA@1239|Firmicutes,4HKU0@91061|Bacilli,1ZHSW@1386|Bacillus 91061|Bacilli S branched-chain amino acid - - - - - - - - - - - - AzlD k141_20572_2 1294265.JCM21738_3838 1.11e-34 124.0 COG1296@1|root,COG1296@2|Bacteria,1TSXD@1239|Firmicutes,4HJCQ@91061|Bacilli,1ZDNM@1386|Bacillus 91061|Bacilli E branched-chain amino acid - - - - - - - - - - - - AzlC k141_12441_1 1294265.JCM21738_4547 1.83e-62 207.0 COG0737@1|root,COG0737@2|Bacteria,1TQCW@1239|Firmicutes,4HAUC@91061|Bacilli,1ZCJ8@1386|Bacillus 91061|Bacilli F Belongs to the 5'-nucleotidase family yunD - 3.1.3.5 ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - 5_nucleotid_C,Metallophos k141_11130_1 1042377.AFPJ01000007_gene1921 9.49e-259 729.0 COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,1RMS8@1236|Gammaproteobacteria,4657M@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) slt GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009274,GO:0016740,GO:0016757,GO:0030203,GO:0030288,GO:0030312,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - ko:K08309 - - - - ko00000,ko01000,ko01011 - GH23 iETEC_1333.ETEC_4747,iPC815.YPO0452 SLT,SLT_L k141_8807_1 218284.CCDN010000001_gene315 6.66e-122 356.0 COG1473@1|root,COG1473@2|Bacteria,1TQ7B@1239|Firmicutes,4HAIK@91061|Bacilli,1ZDIH@1386|Bacillus 91061|Bacilli S amidohydrolase hmrA - - ko:K21613 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 k141_9962_1 1116375.VEJY3_04715 5.5e-317 878.0 COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,1RMH3@1236|Gammaproteobacteria,1XSKE@135623|Vibrionales 135623|Vibrionales O Belongs to the ClpA ClpB family clpA - - ko:K03694 - - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N k141_9962_2 223926.28806000 1.71e-72 217.0 COG2127@1|root,COG2127@2|Bacteria,1MZU8@1224|Proteobacteria,1S8Z7@1236|Gammaproteobacteria,1XXDA@135623|Vibrionales 135623|Vibrionales S Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation clpS - - ko:K06891 - - - - ko00000 - - - ClpS k141_9962_3 223926.28805999 1.91e-48 154.0 COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,1XYAU@135623|Vibrionales 135623|Vibrionales K COG1278 Cold shock proteins cspD GO:0006355,GO:0006950,GO:0008150,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K03704 - - - - ko00000,ko03000 - - - CSD k141_9962_5 1116375.VEJY3_04700 0.0 1290.0 COG2838@1|root,COG2838@2|Bacteria,1MV6Q@1224|Proteobacteria,1RPG4@1236|Gammaproteobacteria,1XUW0@135623|Vibrionales 135623|Vibrionales C Isocitrate dehydrogenase icd - 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 - - - IDH k141_37196_1 1348635.BBJY01000010_gene1360 0.0 1095.0 COG2015@1|root,COG2015@2|Bacteria,1MU82@1224|Proteobacteria,1RMHR@1236|Gammaproteobacteria,1XUC7@135623|Vibrionales 135623|Vibrionales Q COG2015 Alkyl sulfatase and related hydrolases - - - - - - - - - - - - Alkyl_sulf_C,Alkyl_sulf_dimr,Lactamase_B k141_37196_2 1348635.BBJY01000010_gene1359 2.11e-46 155.0 2EJ24@1|root,33CTA@2|Bacteria,1NQ65@1224|Proteobacteria,1SIVK@1236|Gammaproteobacteria,1XY80@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_37196_3 223926.28806878 2.7e-37 127.0 COG2161@1|root,COG2161@2|Bacteria,1N0MZ@1224|Proteobacteria,1SA1X@1236|Gammaproteobacteria,1XZ32@135623|Vibrionales 135623|Vibrionales D Antitoxin component of a toxin-antitoxin (TA) module - - - - - - - - - - - - PhdYeFM_antitox k141_37196_4 1280001.BAOA01000007_gene3973 3.75e-33 118.0 COG3668@1|root,COG3668@2|Bacteria,1NG45@1224|Proteobacteria,1SESF@1236|Gammaproteobacteria,1XZI5@135623|Vibrionales 135623|Vibrionales S ParE toxin of type II toxin-antitoxin system, parDE - - - - - - - - - - - - ParE_toxin k141_30029_1 1196031.ALEG01000012_gene824 1.63e-119 354.0 COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,4HC50@91061|Bacilli,1ZQ98@1386|Bacillus 91061|Bacilli I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) yqjD GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016421,GO:0016874,GO:0016885,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0071704,GO:0072329,GO:1901575 2.1.3.15,6.4.1.3 ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 M00373,M00741 R01859 RC00097,RC00609 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans k141_25416_1 218284.CCDN010000008_gene4247 4.28e-132 401.0 COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H9SA@91061|Bacilli,1ZD7B@1386|Bacillus 91061|Bacilli M COG0744 Membrane carboxypeptidase (penicillin-binding protein) pbp1B - 2.4.1.129 ko:K03693,ko:K12551 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase k141_19440_2 218284.CCDN010000002_gene2030 4.66e-31 119.0 COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,4HA6M@91061|Bacilli,1ZB9G@1386|Bacillus 91061|Bacilli J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family rlmCD GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070041,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.190 ko:K03215 - - - - ko00000,ko01000,ko03009 - - - TRAM,tRNA_U5-meth_tr k141_26765_2 1042377.AFPJ01000009_gene256 1.45e-145 415.0 COG0500@1|root,COG2226@2|Bacteria,1MV4M@1224|Proteobacteria,1RMWY@1236|Gammaproteobacteria,46DC2@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM) cmoA GO:0002097,GO:0002098,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360 - ko:K15256 - - - - ko00000,ko01000,ko03016 - - - Methyltransf_25 k141_26765_3 1279017.AQYJ01000025_gene689 8.08e-199 555.0 COG0500@1|root,COG0500@2|Bacteria,1MVSK@1224|Proteobacteria,1RMQY@1236|Gammaproteobacteria,46D31@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Catalyzes carboxymethyl transfer from carboxy-S- adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs cmoB GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016740,GO:0016741,GO:0016765,GO:0022607,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - ko:K15257 - - - - ko00000,ko01000,ko03016 - - - Methyltransf_9 k141_26765_4 1279017.AQYJ01000025_gene690 7.8e-87 268.0 COG1760@1|root,COG1760@2|Bacteria,1MUZN@1224|Proteobacteria,1RMJZ@1236|Gammaproteobacteria,46637@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG1760 L-serine deaminase sdaA - 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 - R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 - - - SDH_alpha,SDH_beta k141_20573_1 218284.CCDN010000002_gene2121 5.49e-137 400.0 COG0119@1|root,COG0119@2|Bacteria,1TP4Y@1239|Firmicutes,4HA6E@91061|Bacilli,1ZC5T@1386|Bacillus 91061|Bacilli E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) leuA - 2.3.3.13 ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 M00432 R01213 RC00004,RC00470,RC02754 br01601,ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS10690,iYO844.BSU28280 HMGL-like,LeuA_dimer k141_11131_1 1535422.ND16A_1481 8.04e-44 151.0 2DTJU@1|root,33KPS@2|Bacteria,1NJ3F@1224|Proteobacteria,1SIQ5@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_4060_2 218284.CCDN010000001_gene1897 5.75e-169 474.0 COG4589@1|root,COG4589@2|Bacteria,1TT0Q@1239|Firmicutes,4HAMN@91061|Bacilli,1ZBWF@1386|Bacillus 91061|Bacilli S Belongs to the CDS family cdsA GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS06255 CTP_transf_1 k141_539_1 1178540.BA70_18625 3.38e-88 270.0 COG3935@1|root,COG3935@2|Bacteria,1TSHD@1239|Firmicutes,4HIGY@91061|Bacilli,1ZCUE@1386|Bacillus 91061|Bacilli L Conserved phage C-terminus (Phg_2220_C) - - - - - - - - - - - - Phage_rep_org_N,Phg_2220_C k141_8808_1 218284.CCDN010000006_gene3623 5e-109 343.0 COG0457@1|root,COG0457@2|Bacteria,1TSH7@1239|Firmicutes,4HACN@91061|Bacilli,1ZBDH@1386|Bacillus 91061|Bacilli M Tetratricopeptide repeat - - - - - - - - - - - - - k141_33740_3 1042377.AFPJ01000014_gene1662 1.21e-149 424.0 COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,1RNW8@1236|Gammaproteobacteria,464MH@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG0330 Membrane protease subunits, stomatin prohibitin homologs qmcA - - - - - - - - - - - Band_7 k141_33740_4 1279017.AQYJ01000023_gene3111 4.63e-198 565.0 COG1030@1|root,COG1030@2|Bacteria,1MUJN@1224|Proteobacteria,1RN3U@1236|Gammaproteobacteria,465X3@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG1030 Membrane-bound serine protease (ClpP class) nfeD - - ko:K07403 - - - - ko00000 - - - NfeD k141_17053_2 670487.Ocepr_1563 7.02e-44 152.0 COG0327@1|root,COG0327@2|Bacteria,1WI31@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S PFAM NIF3 (NGG1p interacting factor 3) - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - - - - - - - - - - NIF3 k141_18534_2 981383.AEWH01000059_gene2205 8.24e-22 90.5 COG0708@1|root,COG0708@2|Bacteria,1TPFB@1239|Firmicutes,4HAIU@91061|Bacilli 91061|Bacilli L exodeoxyribonuclease III exoA GO:0003674,GO:0003824,GO:0003906,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008296,GO:0008309,GO:0008311,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.11.2 ko:K01142 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Exo_endo_phos k141_12671_1 1219072.VHA01S_074_00150 6.81e-79 243.0 COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,1RMAQ@1236|Gammaproteobacteria,1XVPF@135623|Vibrionales 135623|Vibrionales L COG3547 Transposase and inactivated derivatives - - - - - - - - - - - - DEDD_Tnp_IS110,Transposase_20 k141_14791_2 1279017.AQYJ01000026_gene36 1.24e-09 60.5 COG0008@1|root,COG0008@2|Bacteria,1MUC8@1224|Proteobacteria,1RQ7G@1236|Gammaproteobacteria,464TJ@72275|Alteromonadaceae 1236|Gammaproteobacteria J COG0008 Glutamyl- and glutaminyl-tRNA synthetases glnS GO:0003674,GO:0003824,GO:0004812,GO:0004819,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006425,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.18 ko:K01886 ko00970,ko01100,map00970,map01100 M00359,M00360 R03652 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iECIAI39_1322.ECIAI39_0637 tRNA-synt_1c,tRNA-synt_1c_C k141_6585_1 218284.CCDN010000001_gene1427 2.53e-55 184.0 COG2340@1|root,COG2340@2|Bacteria,1TSUX@1239|Firmicutes,4HDMJ@91061|Bacilli,1ZB45@1386|Bacillus 91061|Bacilli G protein with SCP PR1 domains - - - - - - - - - - - - CAP,CAP_assoc_N,SLH k141_13862_1 1042377.AFPJ01000007_gene1845 7.64e-79 240.0 COG3816@1|root,COG3816@2|Bacteria,1RD5Q@1224|Proteobacteria,1S9CC@1236|Gammaproteobacteria,467ZR@72275|Alteromonadaceae 1236|Gammaproteobacteria T protein conserved in bacteria - - - ko:K09986 - - - - ko00000 - - - DUF1285 k141_13862_2 1042377.AFPJ01000007_gene1846 3.77e-136 388.0 COG1309@1|root,COG1309@2|Bacteria,1RBU9@1224|Proteobacteria,1S2C2@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator tetR7 - - - - - - - - - - - TetR_N,WHG k141_13862_3 266809.PM03_05365 7.13e-18 87.0 COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,2U591@28211|Alphaproteobacteria 28211|Alphaproteobacteria O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides ppiA - 5.2.1.8 ko:K01802,ko:K03768,ko:K09565 ko04020,ko04022,ko05012,ko05016,ko05145,map04020,map04022,map05012,map05016,map05145 - - - ko00000,ko00001,ko01000,ko03110 - - - Pro_isomerase k141_13862_4 1453501.JELR01000001_gene2395 4.28e-173 486.0 COG1946@1|root,COG1946@2|Bacteria,1MV9R@1224|Proteobacteria,1RPFI@1236|Gammaproteobacteria,464I0@72275|Alteromonadaceae 1236|Gammaproteobacteria I Acyl-CoA thioesterase tesB GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016042,GO:0016054,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0042802,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046483,GO:0047617,GO:0051186,GO:0055086,GO:0071704,GO:0072329,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901575 - ko:K10805 ko01040,map01040 - - - ko00000,ko00001,ko01000,ko01004 - - iAF1260.b0452,iB21_1397.B21_00408,iBWG_1329.BWG_0334,iEC55989_1330.EC55989_0466,iECBD_1354.ECBD_3203,iECB_1328.ECB_00404,iECDH10B_1368.ECDH10B_0408,iECDH1ME8569_1439.ECDH1ME8569_0437,iECD_1391.ECD_00404,iECH74115_1262.ECH74115_0541,iECIAI1_1343.ECIAI1_0456,iECIAI39_1322.ECIAI39_0221,iECO103_1326.ECO103_0429,iECO111_1330.ECO111_0485,iECO26_1355.ECO26_0487,iECSE_1348.ECSE_0478,iECSP_1301.ECSP_0520,iECUMN_1333.ECUMN_0492,iECW_1372.ECW_m0524,iECs_1301.ECs0506,iEKO11_1354.EKO11_3394,iETEC_1333.ETEC_0505,iEcDH1_1363.EcDH1_3157,iEcE24377_1341.EcE24377A_0488,iEcHS_1320.EcHS_A0529,iEcSMS35_1347.EcSMS35_0496,iEcolC_1368.EcolC_3163,iG2583_1286.G2583_0564,iJO1366.b0452,iSSON_1240.SSON_0440,iUMNK88_1353.UMNK88_505,iWFL_1372.ECW_m0524,iY75_1357.Y75_RS02335,iZ_1308.Z0564,ic_1306.c0571 4HBT_3,Acyl_CoA_thio k141_13862_5 1279017.AQYJ01000025_gene593 4.8e-137 401.0 COG3975@1|root,COG3975@2|Bacteria,1QX25@1224|Proteobacteria,1RWD8@1236|Gammaproteobacteria,466PD@72275|Alteromonadaceae 1236|Gammaproteobacteria S protease with the C-terminal PDZ domain - - - - - - - - - - - - - k141_5459_1 218284.CCDN010000002_gene2216 5.69e-171 484.0 COG2309@1|root,COG2309@2|Bacteria,1TP65@1239|Firmicutes,4H9W8@91061|Bacilli,1ZCU3@1386|Bacillus 91061|Bacilli E COG2309 Leucyl aminopeptidase (aminopeptidase T) ampS - - ko:K19689 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M29 k141_21989_1 218284.CCDN010000001_gene1447 3.88e-135 394.0 COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,4HAJM@91061|Bacilli,1ZD95@1386|Bacillus 91061|Bacilli P ABC transporter, ATP-binding protein ykoD GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0008150,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085 - ko:K16786,ko:K16787 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran,DUF3744 k141_18535_1 1267580.AF6_1179 6e-22 97.8 COG0175@1|root,COG0175@2|Bacteria,1TQBQ@1239|Firmicutes,4HD3W@91061|Bacilli 91061|Bacilli EH sulfate reduction - - - - - - - - - - - - PAPS_reduct k141_4198_1 218284.CCDN010000009_gene4277 9.37e-145 424.0 COG0449@1|root,COG0449@2|Bacteria,1TPGU@1239|Firmicutes,4H9R4@91061|Bacilli,1ZBI5@1386|Bacillus 91061|Bacilli M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source glmS GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 - R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 - - iSB619.SA_RS11245,iYO844.BSU01780 GATase_6,SIS k141_5460_1 1453501.JELR01000002_gene1258 1.45e-102 325.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RS1Q@1236|Gammaproteobacteria,469PS@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_11423_1 1279017.AQYJ01000023_gene3245 5.68e-75 230.0 COG2836@1|root,COG2836@2|Bacteria,1RIGJ@1224|Proteobacteria,1S5V1@1236|Gammaproteobacteria,466TY@72275|Alteromonadaceae 1236|Gammaproteobacteria S Cytochrome C biogenesis protein transmembrane region braZ - - ko:K09792 - - - - ko00000 - - - DsbD_2 k141_11423_2 1279017.AQYJ01000023_gene3244 1.67e-18 78.2 COG3197@1|root,COG3197@2|Bacteria,1NG90@1224|Proteobacteria,1SGQG@1236|Gammaproteobacteria,46912@72275|Alteromonadaceae 1236|Gammaproteobacteria P protein, possibly involved in nitrogen fixation ccoS - - - - - - - - - - - FixS k141_11423_3 1279017.AQYJ01000023_gene3243 9.9e-54 187.0 COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,464SF@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG2217 Cation transport ATPase ccoI - 3.6.3.4 ko:K01533 - - R00086 RC00002 ko00000,ko01000 3.A.3.5 - - ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase k141_27770_1 221109.22778883 1.83e-43 149.0 COG1280@1|root,COG1280@2|Bacteria,1V1Q5@1239|Firmicutes,4HFVQ@91061|Bacilli,23KDR@182709|Oceanobacillus 91061|Bacilli E LysE type translocator ycgF GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015174,GO:0015181,GO:0015318,GO:0015711,GO:0015802,GO:0015807,GO:0015809,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0034220,GO:0042221,GO:0042493,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902023,GO:1903825,GO:1903826,GO:1905039,GO:1990822 - - - - - - - - - - LysE k141_27770_2 1385511.N783_05405 1.24e-09 58.5 COG3403@1|root,COG3403@2|Bacteria,1US5K@1239|Firmicutes,4HD46@91061|Bacilli,2YA50@289201|Pontibacillus 91061|Bacilli S YqcI/YcgG family - - - ko:K09190 - - - - ko00000 - - - YqcI_YcgG k141_29081_1 218284.CCDN010000001_gene590 2.18e-89 274.0 COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,4H9Q8@91061|Bacilli,1ZBRE@1386|Bacillus 91061|Bacilli D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase tig GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K03545 - - - - ko00000 - - - FKBP_C,Trigger_C,Trigger_N k141_35134_1 864069.MicloDRAFT_00051360 3.83e-57 182.0 COG2963@1|root,COG2963@2|Bacteria,1RHKX@1224|Proteobacteria,2U9TV@28211|Alphaproteobacteria,1JVFR@119045|Methylobacteriaceae 28211|Alphaproteobacteria L Transposase - - - ko:K07483 - - - - ko00000 - - - HTH_Tnp_1 k141_35134_2 1123360.thalar_02506 9.85e-189 529.0 COG2801@1|root,COG2963@1|root,COG2801@2|Bacteria,COG2963@2|Bacteria,1PBHA@1224|Proteobacteria,2TRQF@28211|Alphaproteobacteria 28211|Alphaproteobacteria L COG2801 Transposase and inactivated derivatives - - - - - - - - - - - - HTH_32,rve k141_19661_1 666686.B1NLA3E_13335 3.47e-67 218.0 COG0477@1|root,COG2814@2|Bacteria,1TQ7H@1239|Firmicutes,4HB0I@91061|Bacilli,1ZS7F@1386|Bacillus 91061|Bacilli EGP Major Facilitator Superfamily ydeG3 - - - - - - - - - - - MFS_1,MFS_2,Sugar_tr k141_12673_1 218284.CCDN010000006_gene3655 1.94e-137 416.0 COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,4HAW9@91061|Bacilli,1ZARC@1386|Bacillus 91061|Bacilli L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate uvrA - - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran k141_7652_1 1453501.JELR01000002_gene1539 1.85e-220 619.0 COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,1RM7S@1236|Gammaproteobacteria,4640S@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0739 Membrane proteins related to metalloendopeptidases yebA - - - - - - - - - - - OapA,OapA_N,Peptidase_M23 k141_7652_2 1279017.AQYJ01000020_gene1202 1.69e-206 578.0 COG2377@1|root,COG2377@2|Bacteria,1MV4E@1224|Proteobacteria,1RNTZ@1236|Gammaproteobacteria,464CU@72275|Alteromonadaceae 1236|Gammaproteobacteria O Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling anmK GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237 2.7.1.170 ko:K09001 - - - - ko00000,ko01000 - - iECABU_c1320.ECABU_c18930,iECED1_1282.ECED1_1841,ic_1306.c2032 AnmK k141_7652_5 1279017.AQYJ01000020_gene1204 2.6e-71 217.0 COG1664@1|root,COG1664@2|Bacteria,1PDPX@1224|Proteobacteria,1S9XY@1236|Gammaproteobacteria,46885@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG1664 Integral membrane protein CcmA involved in cell shape determination - - - - - - - - - - - - Bactofilin k141_7652_7 1279017.AQYJ01000020_gene1206 6.21e-105 313.0 COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,1RNMX@1236|Gammaproteobacteria,464RI@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde argC GO:0003674,GO:0003824,GO:0003942,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.38 ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R03443 RC00684 ko00000,ko00001,ko00002,ko01000 - - iSSON_1240.SSON_4131 Semialdhyde_dh,Semialdhyde_dhC k141_30166_1 1116375.VEJY3_14585 3.84e-235 657.0 COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,1RN0R@1236|Gammaproteobacteria,1XSJY@135623|Vibrionales 135623|Vibrionales S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family actP - - ko:K14393 - - - - ko00000,ko02000 2.A.21.7 - - SSF k141_30166_2 1280001.BAOA01000011_gene4250 1.36e-57 179.0 COG4327@1|root,COG4327@2|Bacteria,1N0TK@1224|Proteobacteria,1S8V9@1236|Gammaproteobacteria,1XXSA@135623|Vibrionales 135623|Vibrionales S membrane - - - - - - - - - - - - DUF4212 k141_30166_3 1116375.VEJY3_14575 0.0 1042.0 COG3263@1|root,COG3263@2|Bacteria,1MVKV@1224|Proteobacteria,1RMCA@1236|Gammaproteobacteria,1XTCU@135623|Vibrionales 135623|Vibrionales P K( ) H( ) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels nhaP2 - - ko:K11105 - - - - ko00000,ko02000 2.A.36.6 - - CorC_HlyC,Na_H_Exchanger,TrkA_C k141_30166_4 223926.28807892 5.67e-139 394.0 COG2197@1|root,COG2197@2|Bacteria,1P4TD@1224|Proteobacteria,1RU35@1236|Gammaproteobacteria,1XV43@135623|Vibrionales 135623|Vibrionales K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - - - - - - - - - - GerE,Response_reg k141_27771_1 218284.CCDN010000001_gene1963 2.59e-21 91.3 COG1600@1|root,COG1600@2|Bacteria,1TP6Q@1239|Firmicutes,4HAEW@91061|Bacilli,1ZC1W@1386|Bacillus 91061|Bacilli C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) queG GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 ko:K18979 - - - - ko00000,ko01000,ko03016 - - - DUF1730,Fer4_16,HEAT_2 k141_11424_1 1042377.AFPJ01000032_gene2776 1.09e-99 293.0 2940Y@1|root,2ZRFS@2|Bacteria,1RF8A@1224|Proteobacteria,1RZCB@1236|Gammaproteobacteria 1236|Gammaproteobacteria U L-alanine exporter AlaE alaE GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015077,GO:0015078,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015562,GO:0015672,GO:0015711,GO:0015804,GO:0015807,GO:0015808,GO:0015849,GO:0016020,GO:0022804,GO:0022857,GO:0022890,GO:0032328,GO:0034220,GO:0034639,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:0098660,GO:0098662,GO:1902475,GO:1902600,GO:1903825,GO:1905039 - - - - - - - - - - AlaE k141_6587_1 1128421.JAGA01000004_gene2660 6e-129 386.0 COG1653@1|root,COG1653@2|Bacteria 2|Bacteria G carbohydrate transport aglE - - ko:K10232 ko02010,map02010 M00201 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.32,3.A.1.1.8 - - SBP_bac_1,SBP_bac_8 k141_21991_1 1279017.AQYJ01000019_gene1498 1.17e-93 279.0 COG2885@1|root,COG2885@2|Bacteria,1RIG3@1224|Proteobacteria,1S5WW@1236|Gammaproteobacteria,46CH4@72275|Alteromonadaceae 1236|Gammaproteobacteria M OmpA family - - - - - - - - - - - - DUF4398,OmpA k141_12674_1 1231057.AMGD01000004_gene2919 1.03e-47 155.0 COG2721@1|root,COG2721@2|Bacteria 2|Bacteria G sulfolactate sulfo-lyase activity uxaA - 4.2.1.7,4.4.1.24 ko:K01685,ko:K16845,ko:K16849 ko00040,ko00270,ko01100,map00040,map00270,map01100 M00631 R01540,R07633 RC00543,RC01785 ko00000,ko00001,ko00002,ko01000 - - - GD_AH_C,SAF k141_12674_2 665959.HMPREF1013_00161 7.59e-43 149.0 COG2721@1|root,COG2721@2|Bacteria,1TPTX@1239|Firmicutes,4HANN@91061|Bacilli,1ZR3J@1386|Bacillus 91061|Bacilli G D-galactarate dehydratase / Altronate hydrolase, C terminus - - 4.4.1.24 ko:K16846 ko00270,map00270 - R07633 RC01785 ko00000,ko00001,ko01000 - - - GD_AH_C k141_14794_2 521000.PROVRETT_05998 4.4e-34 125.0 COG1403@1|root,COG1403@2|Bacteria,1RHFB@1224|Proteobacteria,1S4HW@1236|Gammaproteobacteria,3Z94X@586|Providencia 1236|Gammaproteobacteria V Bacteriophage Lambda NinG protein - - - - - - - - - - - - NinG k141_25694_1 218284.CCDN010000002_gene2748 1.5e-255 706.0 COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,4H9M0@91061|Bacilli,1ZEIA@1386|Bacillus 91061|Bacilli J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family - - 2.1.1.190 ko:K03215 - - - - ko00000,ko01000,ko03009 - - - tRNA_U5-meth_tr k141_16041_1 218284.CCDN010000001_gene162 9.28e-211 586.0 COG1294@1|root,COG1294@2|Bacteria,1TPYX@1239|Firmicutes,4HA9T@91061|Bacilli,1ZCH6@1386|Bacillus 91061|Bacilli C COG1294 Cytochrome bd-type quinol oxidase, subunit 2 cydB - 1.10.3.14 ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - Cyt_bd_oxida_II k141_16041_2 1132442.KB889752_gene617 3.67e-14 72.0 COG1271@1|root,COG1271@2|Bacteria,1TRH4@1239|Firmicutes,4HA19@91061|Bacilli,1ZBAG@1386|Bacillus 91061|Bacilli C oxidase, subunit cydA - 1.10.3.14 ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - Cyt_bd_oxida_I k141_26993_1 1395513.P343_09695 1.04e-78 237.0 28NQ2@1|root,2ZBPT@2|Bacteria,1V2UY@1239|Firmicutes,4HGA8@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - k141_12684_4 1499686.BN1079_02618 2.39e-138 394.0 COG1788@1|root,COG1788@2|Bacteria,1MVEI@1224|Proteobacteria,1RNXB@1236|Gammaproteobacteria 1236|Gammaproteobacteria I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit scoA - 2.8.3.5 ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 - R00410 RC00014 ko00000,ko00001,ko01000 - - iJN746.PP_3122 CoA_trans k141_12684_5 1333856.L686_03060 1.15e-118 349.0 COG0583@1|root,COG0583@2|Bacteria,1MUWX@1224|Proteobacteria,1RMVV@1236|Gammaproteobacteria,1Z27G@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria K Bacterial regulatory helix-turn-helix protein, lysR family - - - ko:K17737 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate k141_36157_2 666686.B1NLA3E_06725 4.86e-19 79.7 2DR6C@1|root,33ACS@2|Bacteria,1VM75@1239|Firmicutes,4HR6M@91061|Bacilli,1ZJYN@1386|Bacillus 91061|Bacilli S YlzJ-like protein - - - - - - - - - - - - YlzJ k141_755_1 1280946.HY29_00140 4.16e-19 90.1 COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,2TRWB@28211|Alphaproteobacteria,43WQ8@69657|Hyphomonadaceae 28211|Alphaproteobacteria E Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia trpE - 4.1.3.27 ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Anth_synt_I_N,Chorismate_bind k141_1720_1 240302.BN982_02802 2e-82 256.0 COG0477@1|root,COG2814@2|Bacteria,1TPW3@1239|Firmicutes,4H9R6@91061|Bacilli,3NDIQ@45667|Halobacillus 91061|Bacilli EGP Major Facilitator Superfamily yfkF - - - - - - - - - - - MFS_1,MFS_1_like,Sugar_tr k141_5475_1 398767.Glov_2401 1.51e-48 169.0 COG1775@1|root,COG1775@2|Bacteria,1NNW9@1224|Proteobacteria,42RTN@68525|delta/epsilon subdivisions,2WNYI@28221|Deltaproteobacteria,43V0Q@69541|Desulfuromonadales 28221|Deltaproteobacteria E 2-hydroxyglutaryl-CoA dehydratase, D-component - - 1.3.7.8 ko:K04112 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00541 R02451 RC00002,RC01839 ko00000,ko00001,ko00002,ko01000 - - - HGD-D k141_23291_1 42565.FP66_01850 1e-64 219.0 COG2199@1|root,COG5000@1|root,COG2199@2|Bacteria,COG5000@2|Bacteria,1RE50@1224|Proteobacteria,1S3P4@1236|Gammaproteobacteria 1236|Gammaproteobacteria T COG2199 FOG GGDEF domain - - - - - - - - - - - - GGDEF,PAS,PAS_3,PAS_4,PAS_8,PAS_9,dCache_1 k141_23291_2 42565.FP66_01840 3.92e-28 109.0 2F0U7@1|root,33TW5@2|Bacteria,1NVEY@1224|Proteobacteria,1SNFT@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_7668_1 439292.Bsel_0477 7.85e-24 99.0 2A8A0@1|root,30XBB@2|Bacteria,1V5X0@1239|Firmicutes,4HHA9@91061|Bacilli 91061|Bacilli S Domain of unknown function (DUF3784) - - - - - - - - - - - - DUF3784,bPH_5 k141_30176_1 218284.CCDN010000001_gene1570 1.78e-128 382.0 COG1960@1|root,COG1960@2|Bacteria,1TQC8@1239|Firmicutes,4HC6Y@91061|Bacilli,1ZCXT@1386|Bacillus 91061|Bacilli I Acyl-CoA dehydrogenase, middle domain - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M k141_32564_2 406124.ACPC01000014_gene816 4.38e-59 184.0 COG2201@1|root,COG2201@2|Bacteria,1V71X@1239|Firmicutes,4HITX@91061|Bacilli,1ZHDB@1386|Bacillus 91061|Bacilli T cheY-homologous receiver domain yneI - - ko:K03413 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - Response_reg k141_32564_3 218284.CCDN010000001_gene1782 1.15e-86 257.0 COG4846@1|root,COG4846@2|Bacteria,1V7C6@1239|Firmicutes,4HGXI@91061|Bacilli,1ZG68@1386|Bacillus 91061|Bacilli O COG4846 Membrane protein involved in cytochrome C biogenesis yneJ - - - - - - - - - - - DUF1453 k141_32564_4 218284.CCDN010000001_gene1781 8.73e-66 204.0 COG1994@1|root,COG1994@2|Bacteria,1V8QC@1239|Firmicutes,4HK02@91061|Bacilli,1ZQQW@1386|Bacillus 91061|Bacilli S Peptidase M50 ywmF - - - - - - - - - - - Peptidase_M50 k141_11445_2 1134413.ANNK01000120_gene2048 2.8e-31 118.0 COG2197@1|root,COG2197@2|Bacteria 2|Bacteria K response regulator - - - - - - - - - - - - HNH_3 k141_23292_1 1453501.JELR01000002_gene162 1.67e-10 60.1 COG2981@1|root,COG2981@2|Bacteria,1MVFT@1224|Proteobacteria,1RMQT@1236|Gammaproteobacteria,4671M@72275|Alteromonadaceae 1236|Gammaproteobacteria E High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway cysZ GO:0000096,GO:0000097,GO:0000103,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006520,GO:0006534,GO:0006790,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0008150,GO:0008152,GO:0008271,GO:0008272,GO:0008324,GO:0008509,GO:0008512,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009675,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015103,GO:0015116,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015296,GO:0015318,GO:0015672,GO:0015698,GO:0016020,GO:0016021,GO:0016053,GO:0019344,GO:0019752,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034220,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044425,GO:0044459,GO:0044464,GO:0046394,GO:0051179,GO:0051234,GO:0055085,GO:0071704,GO:0071944,GO:0072348,GO:0098655,GO:0098656,GO:0098660,GO:0098661,GO:0098662,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901682,GO:1902358,GO:1902600 - ko:K06203 - - - - ko00000 - - iJR904.b2413,iYL1228.KPN_02760 EI24 k141_23292_2 1453501.JELR01000002_gene161 2.87e-56 176.0 2D7C6@1|root,32TNS@2|Bacteria,1MZUP@1224|Proteobacteria,1SA42@1236|Gammaproteobacteria,46CTJ@72275|Alteromonadaceae 1236|Gammaproteobacteria S aminopeptidase IV02_13490 - - - - - - - - - - - - k141_5477_1 1042377.AFPJ01000032_gene2810 6.43e-100 299.0 COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,1RN4I@1236|Gammaproteobacteria,46412@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) aroB GO:0000166,GO:0003674,GO:0003824,GO:0003856,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0051287,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.4 ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03083 RC00847 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b3389,iBWG_1329.BWG_3080,iECDH10B_1368.ECDH10B_3564,iECDH1ME8569_1439.ECDH1ME8569_3268,iECNA114_1301.ECNA114_3486,iEcDH1_1363.EcDH1_0324,iJO1366.b3389,iJR904.b3389,iY75_1357.Y75_RS20275 DHQ_synthase k141_12685_1 42565.FP66_11150 3.96e-74 234.0 COG0516@1|root,COG0516@2|Bacteria,1MUJM@1224|Proteobacteria,1RMT8@1236|Gammaproteobacteria,1XH9A@135619|Oceanospirillales 135619|Oceanospirillales F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth guaB - 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 - - - CBS,IMPDH,NMO k141_33923_1 1279017.AQYJ01000029_gene3422 2.13e-89 271.0 COG0084@1|root,COG0084@2|Bacteria,1MW5C@1224|Proteobacteria,1RP5T@1236|Gammaproteobacteria,46719@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG0084 Mg-dependent DNase yjjV - - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase k141_13882_1 518766.Rmar_2596 1.46e-135 396.0 COG0309@1|root,COG0309@2|Bacteria,4NG57@976|Bacteroidetes 976|Bacteroidetes O TIGRFAM hydrogenase expression formation protein HypE - - - ko:K04655 - - - - ko00000 - - - AIRS,AIRS_C k141_11446_2 218284.CCDN010000001_gene584 2.35e-129 372.0 COG0796@1|root,COG0796@2|Bacteria,1TPPR@1239|Firmicutes,4HA46@91061|Bacilli,1ZBC9@1386|Bacillus 91061|Bacilli M Provides the (R)-glutamate required for cell wall biosynthesis murI GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0034645,GO:0036361,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 3.6.1.66,5.1.1.3 ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 - R00260,R00426,R00720,R01855,R02100,R02720,R03531 RC00002,RC00302 ko00000,ko00001,ko01000,ko01011 - - iYO844.BSU28390 Asp_Glu_race k141_31376_1 930169.B5T_03658 1.22e-103 306.0 2EBCQ@1|root,335DF@2|Bacteria,1R1Z7@1224|Proteobacteria,1T5DV@1236|Gammaproteobacteria 1236|Gammaproteobacteria S PhoP regulatory network protein YrbL - - - - - - - - - - - - YrbL-PhoP_reg k141_31376_2 1117647.M5M_12820 4.54e-158 453.0 COG0438@1|root,COG0438@2|Bacteria,1QF9A@1224|Proteobacteria,1RMDT@1236|Gammaproteobacteria,1J5KG@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Glycosyl transferases group 1 capM2_2 - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 k141_24354_1 218284.CCDN010000001_gene1217 1.59e-88 272.0 COG0624@1|root,COG0624@2|Bacteria,1TQS9@1239|Firmicutes,4HDHW@91061|Bacilli,1ZBDC@1386|Bacillus 91061|Bacilli E Acetylornithine deacetylase yodQ - 3.5.1.16,3.5.1.18 ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R00669,R02734,R09107 RC00064,RC00090,RC00300 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20,Peptidase_M28 k141_32565_1 1294265.JCM21738_119 9.24e-67 203.0 COG4401@1|root,COG4401@2|Bacteria,1VAID@1239|Firmicutes,4HKTN@91061|Bacilli,1ZH0S@1386|Bacillus 91061|Bacilli E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis aroH GO:0003674,GO:0003824,GO:0004106,GO:0006082,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044281,GO:0046417,GO:0071704 5.4.99.5 ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024,M00025 R01715 RC03116 ko00000,ko00001,ko00002,ko01000 - - - CM_1 k141_32565_2 935837.JAEK01000011_gene198 3.79e-91 278.0 COG0079@1|root,COG0079@2|Bacteria,1TPUV@1239|Firmicutes,4HA1H@91061|Bacilli,1ZBYJ@1386|Bacillus 91061|Bacilli E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily hisC - 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k141_4216_1 218284.CCDN010000006_gene3516 4.97e-59 186.0 COG2364@1|root,COG2364@2|Bacteria,1V3NC@1239|Firmicutes,4HGRQ@91061|Bacilli,1ZCBH@1386|Bacillus 91061|Bacilli S Membrane - - - ko:K07149 - - - - ko00000 - - - YitT_membrane k141_4216_2 218284.CCDN010000006_gene3517 2.25e-17 80.9 COG3263@1|root,COG3263@2|Bacteria,1TQPJ@1239|Firmicutes,4HC8I@91061|Bacilli,1ZC6H@1386|Bacillus 91061|Bacilli P COG3263 NhaP-type Na H and K H antiporters with a unique C-terminal domain cvrA - - ko:K11105 - - - - ko00000,ko02000 2.A.36.6 - - Na_H_Exchanger,TrkA_C k141_33924_1 218284.CCDN010000002_gene2724 9.16e-102 315.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1TQ85@1239|Firmicutes,4HAC0@91061|Bacilli,1ZR0Z@1386|Bacillus 91061|Bacilli EU Dienelactone hydrolase family - - - - - - - - - - - - PD40,Peptidase_S9,Peptidase_S9_N k141_24355_1 218284.CCDN010000001_gene1466 1.3e-159 454.0 COG1960@1|root,COG1960@2|Bacteria,1UZKG@1239|Firmicutes,4HA6B@91061|Bacilli,1ZEAS@1386|Bacillus 91061|Bacilli I Acyl-CoA dehydrogenase, N-terminal domain mmgC_3 - 1.3.8.7 ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_1725_1 501479.ACNW01000103_gene628 1.12e-112 337.0 COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,2TQYK@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit atpA - 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N k141_25706_1 223926.28808978 1.86e-112 342.0 COG0784@1|root,COG0784@2|Bacteria,1QUZH@1224|Proteobacteria,1T2JI@1236|Gammaproteobacteria,1XT5E@135623|Vibrionales 135623|Vibrionales T cheY-homologous receiver domain - - - - - - - - - - - - Response_reg,TPR_19 k141_25706_2 1280001.BAOA01000213_gene17 3.44e-154 465.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1Y0NK@135623|Vibrionales 135623|Vibrionales NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - - - - - - - - - - MCPsignal k141_25706_3 1116375.VEJY3_19156 1.26e-118 342.0 COG2197@1|root,COG2197@2|Bacteria,1Q0DT@1224|Proteobacteria,1RY1Z@1236|Gammaproteobacteria,1XWAG@135623|Vibrionales 135623|Vibrionales K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - ko:K07688 ko02020,map02020 - - - ko00000,ko00001,ko02022 - - - GerE,Response_reg k141_32825_1 1160707.AJIK01000010_gene2472 2.13e-24 100.0 COG3677@1|root,COG3677@2|Bacteria,1TTUH@1239|Firmicutes,4IDU8@91061|Bacilli,26I08@186818|Planococcaceae 91061|Bacilli L ISXO2-like transposase domain - - - - - - - - - - - - DDE_Tnp_IS1595 k141_18901_1 1173028.ANKO01000030_gene3283 1.92e-48 168.0 COG0438@1|root,COG0438@2|Bacteria,1G1X1@1117|Cyanobacteria,1HH59@1150|Oscillatoriales 1117|Cyanobacteria M Glycosyl transferase 4-like domain - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 k141_966_7 1116375.VEJY3_08340 4.61e-54 171.0 2EAFQ@1|root,334J3@2|Bacteria,1N70W@1224|Proteobacteria,1T69T@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_966_8 1127673.GLIP_3601 2.6e-68 209.0 COG3791@1|root,COG3791@2|Bacteria,1N031@1224|Proteobacteria,1S8W1@1236|Gammaproteobacteria,467D7@72275|Alteromonadaceae 1236|Gammaproteobacteria S Glutathione-dependent formaldehyde-activating enzyme - - - - - - - - - - - - GFA k141_966_9 1116375.VEJY3_08335 1.49e-132 379.0 COG0730@1|root,COG0730@2|Bacteria,1RAG9@1224|Proteobacteria,1S2RX@1236|Gammaproteobacteria,1XWQG@135623|Vibrionales 135623|Vibrionales S membrane transporter protein - - - - - - - - - - - - TauE k141_34156_1 981383.AEWH01000012_gene3876 4.35e-56 188.0 COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,4HA1G@91061|Bacilli 91061|Bacilli G COG0366 Glycosidases malL - 3.2.1.10,3.2.1.20 ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00028,R00801,R00802,R01718,R01791,R06087,R06088,R06199 RC00028,RC00049,RC00059,RC00077,RC00451 ko00000,ko00001,ko01000 - GH13,GH31 - Alpha-amylase,Malt_amylase_C k141_34156_2 935837.JAEK01000006_gene4266 2.1e-30 116.0 COG1609@1|root,COG1609@2|Bacteria,1TPZM@1239|Firmicutes,4H9ZT@91061|Bacilli,1ZB2U@1386|Bacillus 91061|Bacilli K Transcriptional regulator malR - - - - - - - - - - - LacI,Peripla_BP_3 k141_17389_3 28072.Nos7524_4621 1.12e-60 230.0 COG0823@1|root,COG2304@1|root,COG3209@1|root,COG3210@1|root,COG0823@2|Bacteria,COG2304@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,1GQ0G@1117|Cyanobacteria,1HN8U@1161|Nostocales 1117|Cyanobacteria MU Dystroglycan-type cadherin-like domains. - - - - - - - - - - - - Cadherin,He_PIG,RHS_repeat k141_16274_1 1532557.JL37_05215 2.03e-07 52.8 COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VHFW@28216|Betaproteobacteria,3T5F9@506|Alcaligenaceae 28216|Betaproteobacteria C CoA-transferase - - - - - - - - - - - - CoA_transf_3 k141_16274_2 288000.BBta_1008 2.61e-19 85.9 COG1045@1|root,COG1045@2|Bacteria,1RM0T@1224|Proteobacteria,2U8N8@28211|Alphaproteobacteria,3K4GZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Bacterial transferase hexapeptide (six repeats) - - 2.3.1.30 ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 M00021 R00586 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 - - - Hexapep k141_37554_1 1294265.JCM21738_1661 2.81e-112 329.0 COG0391@1|root,COG0391@2|Bacteria,1TPNV@1239|Firmicutes,4HA0Z@91061|Bacilli,1ZB2R@1386|Bacillus 91061|Bacilli S Required for morphogenesis under gluconeogenic growth conditions yvcK - - - - - - - - - - - UPF0052 k141_3159_1 218284.CCDN010000001_gene1633 2.28e-129 382.0 COG1232@1|root,COG1232@2|Bacteria,1TQ6W@1239|Firmicutes,4HAUG@91061|Bacilli,1ZANK@1386|Bacillus 91061|Bacilli H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX hemG - 1.3.3.15,1.3.3.4 ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03222,R04178 RC00885 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS09325 Amino_oxidase k141_14235_1 935836.JAEL01000076_gene3070 6.41e-53 177.0 29H5Q@1|root,30439@2|Bacteria,1V63Q@1239|Firmicutes,4HHR2@91061|Bacilli,1ZE9T@1386|Bacillus 91061|Bacilli S Nuclease-related domain - - - - - - - - - - - - NERD k141_34157_1 1279017.AQYJ01000027_gene1591 2.27e-112 361.0 COG0643@1|root,COG0784@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,4650G@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0643 Chemotaxis protein histidine kinase and related kinases chpA - - ko:K02487,ko:K06596 ko02020,ko02025,map02020,map02025 M00507 - - ko00000,ko00001,ko00002,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg k141_969_1 1227484.C471_03163 4.06e-11 65.9 COG0352@1|root,arCOG01089@2157|Archaea,2XSTA@28890|Euryarchaeota,23U3A@183963|Halobacteria 183963|Halobacteria H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) thiE - 2.5.1.3 ko:K00788 ko00730,ko01100,map00730,map01100 M00127 R03223,R10712 RC00224,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 - - - TMP-TENI k141_19924_1 1219076.N646_3256 4.05e-132 386.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1XVEB@135623|Vibrionales 135623|Vibrionales T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - - - - - - - - - - HTH_8,Response_reg,Sigma54_activat k141_19924_2 1219077.VAZ01S_035_00510 3.36e-45 159.0 COG2885@1|root,COG2885@2|Bacteria,1N6C8@1224|Proteobacteria,1SAU6@1236|Gammaproteobacteria,1XWYH@135623|Vibrionales 135623|Vibrionales N Belongs to the ompA family - - - ko:K21218 ko02040,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - OmpA k141_30343_1 218284.CCDN010000001_gene1682 6.26e-139 398.0 COG1125@1|root,COG1125@2|Bacteria,1TPV8@1239|Firmicutes,4H9SI@91061|Bacilli,1ZBIG@1386|Bacillus 91061|Bacilli E COG1125 ABC-type proline glycine betaine transport systems, ATPase components proV - - ko:K05847 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - ABC_tran,CBS k141_18942_1 1403313.AXBR01000015_gene2146 1.08e-11 62.8 COG4912@1|root,COG4912@2|Bacteria,1UP0J@1239|Firmicutes,4HDFV@91061|Bacilli,1ZBU5@1386|Bacillus 91061|Bacilli L DNA alkylation repair enzyme - - - - - - - - - - - - DNA_alkylation k141_18942_2 1034347.CAHJ01000005_gene2461 4.35e-43 141.0 2C8U7@1|root,32RMX@2|Bacteria,1VB3M@1239|Firmicutes,4HKS9@91061|Bacilli,1ZI3K@1386|Bacillus 91061|Bacilli S MFS transporter - - - - - - - - - - - - - k141_25964_2 218284.CCDN010000007_gene3923 5.37e-213 592.0 COG0842@1|root,COG0842@2|Bacteria,1TQG7@1239|Firmicutes,4H9MK@91061|Bacilli,1ZAPY@1386|Bacillus 91061|Bacilli V COG0842 ABC-type multidrug transport system, permease component - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane,ABC2_membrane_3 k141_25964_3 218284.CCDN010000007_gene3922 5.56e-11 60.8 COG1309@1|root,COG1309@2|Bacteria,1V3R8@1239|Firmicutes,4HBEK@91061|Bacilli,1ZDP2@1386|Bacillus 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - TetR_N k141_10433_1 218284.CCDN010000001_gene1636 1.87e-86 270.0 COG1231@1|root,COG1231@2|Bacteria,1TRJC@1239|Firmicutes,4HBN4@91061|Bacilli,1ZBU2@1386|Bacillus 91061|Bacilli E COG1231 Monoamine oxidase - - 1.4.3.4 ko:K00274 ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034 M00135 R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354 RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713 ko00000,ko00001,ko00002,ko01000 - - - Amino_oxidase k141_32849_1 1042377.AFPJ01000055_gene957 3.39e-95 301.0 COG2366@1|root,COG2366@2|Bacteria,1MVMH@1224|Proteobacteria,1RMPX@1236|Gammaproteobacteria,464PP@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG2366 Protein related to penicillin acylase pvdQ - 3.5.1.97 ko:K07116 - - - - ko00000,ko01000 - - - Penicil_amidase k141_22317_1 1294265.JCM21738_2416 1.66e-270 746.0 COG1120@1|root,COG1120@2|Bacteria,1TP2Q@1239|Firmicutes,4HA28@91061|Bacilli,1ZASR@1386|Bacillus 91061|Bacilli HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components yvrA - 3.6.3.34 ko:K02013 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 - - ABC_tran,CbiZ k141_14237_1 218284.CCDN010000001_gene735 3.54e-118 345.0 COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,4H9KA@91061|Bacilli,1ZC0R@1386|Bacillus 91061|Bacilli O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins dnaJ - - ko:K03686 - - - - ko00000,ko03029,ko03110 - - - DnaJ,DnaJ_C,DnaJ_CXXCXGXG k141_35422_1 1116375.VEJY3_00850 2.38e-223 616.0 COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,1RMZ5@1236|Gammaproteobacteria,1XSK3@135623|Vibrionales 135623|Vibrionales M Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)- (lauroyl)-lipid IV(A) lpxL - 2.3.1.241 ko:K02517 ko00540,ko01100,map00540,map01100 M00060 R05146 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Lip_A_acyltrans k141_35422_2 1116375.VEJY3_00855 3.7e-124 355.0 COG1309@1|root,COG1309@2|Bacteria,1MWF7@1224|Proteobacteria,1RPZ6@1236|Gammaproteobacteria,1XTMS@135623|Vibrionales 135623|Vibrionales D Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions slmA GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - ko:K05501 - - - - ko00000,ko03000,ko03036 - - - TetR_N k141_25965_1 935836.JAEL01000043_gene4305 1.45e-117 349.0 COG0364@1|root,COG0364@2|Bacteria,1TPYF@1239|Firmicutes,4HA73@91061|Bacilli,1ZCZ3@1386|Bacillus 91061|Bacilli G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone zwf - 1.1.1.363,1.1.1.49 ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 M00004,M00006,M00008 R00835,R02736,R10907 RC00001,RC00066 ko00000,ko00001,ko00002,ko01000,ko04147 - - - G6PD_C,G6PD_N k141_22318_1 1279017.AQYJ01000024_gene982 2.39e-85 268.0 COG0204@1|root,COG3176@1|root,COG0204@2|Bacteria,COG3176@2|Bacteria,1MWIM@1224|Proteobacteria,1RQD4@1236|Gammaproteobacteria,464MD@72275|Alteromonadaceae 1236|Gammaproteobacteria I Acyltransferase - - - - - - - - - - - - Acetyltransf_5,Acyltransferase k141_34158_1 717774.Marme_4041 1.93e-16 80.9 COG0524@1|root,COG0524@2|Bacteria,1MX38@1224|Proteobacteria,1RRWT@1236|Gammaproteobacteria,1XJAW@135619|Oceanospirillales 135619|Oceanospirillales G pfkB family carbohydrate kinase scrK - 2.7.1.4 ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 - R00760,R00867,R03920 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB k141_34158_2 1121936.AUHI01000022_gene2710 8.94e-22 94.4 COG1741@1|root,COG1741@2|Bacteria,1TQDV@1239|Firmicutes,4HE4S@91061|Bacilli 91061|Bacilli S Belongs to the pirin family - - - ko:K06911 - - - - ko00000 - - - Pirin,Pirin_C k141_23665_1 1123267.JONN01000001_gene2370 2.2e-08 57.0 COG3185@1|root,COG3185@2|Bacteria,1MUVZ@1224|Proteobacteria,2TRCC@28211|Alphaproteobacteria,2K0BD@204457|Sphingomonadales 204457|Sphingomonadales E 4-hydroxyphenylpyruvate dioxygenase hppD - 1.13.11.27 ko:K00457 ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100 M00044 R01372,R02521 RC00505,RC00738 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Glyoxalase,Glyoxalase_5 k141_23665_4 1384056.N787_02940 1.02e-210 588.0 COG1902@1|root,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,1RMII@1236|Gammaproteobacteria,1X3AF@135614|Xanthomonadales 135614|Xanthomonadales C Oxidoreductase - - - - - - - - - - - - Oxidored_FMN k141_23665_5 1453501.JELR01000001_gene2115 2.87e-127 373.0 COG0668@1|root,COG0668@2|Bacteria,1N596@1224|Proteobacteria,1RQZP@1236|Gammaproteobacteria,465C6@72275|Alteromonadaceae 1236|Gammaproteobacteria M Mechanosensitive ion channel - - - - - - - - - - - - MS_channel,TM_helix k141_18944_2 1453501.JELR01000001_gene2508 8.89e-23 97.8 28IUR@1|root,2Z8TE@2|Bacteria,1NW7C@1224|Proteobacteria,1RP4W@1236|Gammaproteobacteria,465G0@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_37556_1 1294265.JCM21738_1903 3.92e-100 292.0 2CY4V@1|root,32T3F@2|Bacteria,1VDQ0@1239|Firmicutes,4HKEQ@91061|Bacilli,1ZIB4@1386|Bacillus 91061|Bacilli S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) - - - - - - - - - - - - Spore_YhcN_YlaJ k141_14239_1 218284.CCDN010000005_gene3244 1.7e-115 343.0 COG0004@1|root,COG0004@2|Bacteria,1TQYG@1239|Firmicutes,4HBGK@91061|Bacilli,1ZB5S@1386|Bacillus 91061|Bacilli P Ammonium transporter amtB - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - Ammonium_transp k141_19927_1 926550.CLDAP_30860 4.19e-26 111.0 COG0147@1|root,COG0147@2|Bacteria,2G5M7@200795|Chloroflexi 200795|Chloroflexi H Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia trpE - 4.1.3.27 ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Anth_synt_I_N,Chorismate_bind k141_20938_1 218284.CCDN010000001_gene1488 4.25e-105 316.0 COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,4H9SZ@91061|Bacilli,1ZAX7@1386|Bacillus 91061|Bacilli E Sodium alanine symporter glnT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03310,ko:K11626 ko02020,map02020 - - - ko00000,ko00001 2.A.25 - - Na_Ala_symp k141_32851_1 1453501.JELR01000002_gene844 2.85e-33 125.0 COG1904@1|root,COG1904@2|Bacteria,1MVRI@1224|Proteobacteria,1RMRR@1236|Gammaproteobacteria,464VQ@72275|Alteromonadaceae 1236|Gammaproteobacteria G Glucuronate isomerase uxaC GO:0005975,GO:0005996,GO:0006063,GO:0006064,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0019585,GO:0019586,GO:0019698,GO:0019752,GO:0032787,GO:0042839,GO:0042840,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046365,GO:0046395,GO:0046396,GO:0046397,GO:0071704,GO:0072329,GO:1901575 5.3.1.12 ko:K01812 ko00040,ko01100,map00040,map01100 M00061,M00631 R01482,R01983 RC00376 ko00000,ko00001,ko00002,ko01000 - - iPC815.YPO0579,iSbBS512_1146.SbBS512_E3528 UxaC k141_12887_1 472759.Nhal_1422 1.54e-18 88.6 COG4961@1|root,COG4961@2|Bacteria,1R58C@1224|Proteobacteria,1S1A4@1236|Gammaproteobacteria 1236|Gammaproteobacteria U Putative Flp pilus-assembly TadE/G-like - - - - - - - - - - - - Tad k141_12887_2 425104.Ssed_2369 5.34e-11 65.5 COG4961@1|root,COG4961@2|Bacteria,1NCGE@1224|Proteobacteria,1SDQ1@1236|Gammaproteobacteria,2QCP6@267890|Shewanellaceae 1236|Gammaproteobacteria U TadE-like protein - - - - - - - - - - - - TadE k141_12887_3 223926.28807412 6.86e-29 111.0 COG4961@1|root,COG4961@2|Bacteria,1PRDK@1224|Proteobacteria,1TC3B@1236|Gammaproteobacteria,1XYH0@135623|Vibrionales 135623|Vibrionales U TadE-like protein VP2414 - - - - - - - - - - - TadE k141_12887_4 1348635.BBJY01000008_gene1743 2.45e-134 398.0 COG4963@1|root,COG4963@2|Bacteria,1MWNY@1224|Proteobacteria,1S6CE@1236|Gammaproteobacteria,1XVBI@135623|Vibrionales 135623|Vibrionales U COG4963 Flp pilus assembly protein, ATPase CpaE - - - ko:K02282 - - - - ko00000,ko02035,ko02044 - - - AAA_31 k141_12887_5 1348635.BBJY01000008_gene1742 5.28e-272 754.0 COG4962@1|root,COG4962@2|Bacteria,1R7EN@1224|Proteobacteria,1RP9G@1236|Gammaproteobacteria,1XSF1@135623|Vibrionales 135623|Vibrionales U COG4962 Flp pilus assembly protein, ATPase CpaF - - - ko:K02283 - - - - ko00000,ko02035,ko02044 - - - T2SSE k141_12887_7 1348635.BBJY01000008_gene1740 3.66e-107 322.0 COG2064@1|root,COG2064@2|Bacteria,1MWAZ@1224|Proteobacteria,1SZWZ@1236|Gammaproteobacteria,1XSF0@135623|Vibrionales 135623|Vibrionales NU COG2064 Flp pilus assembly protein TadC VV2651 - - ko:K12511 - - - - ko00000,ko02044 - - - T2SSF k141_12887_8 1348635.BBJY01000008_gene1739 1.07e-100 306.0 COG0457@1|root,COG0457@2|Bacteria,1NFC8@1224|Proteobacteria,1RWMG@1236|Gammaproteobacteria,1XVGU@135623|Vibrionales 135623|Vibrionales S COG0457 FOG TPR repeat VP2409 - - - - - - - - - - - TPR_1,TPR_16,TPR_17,TPR_2,TPR_8 k141_12887_9 1219076.N646_1513 1.04e-225 627.0 COG2059@1|root,COG2059@2|Bacteria,1MUBW@1224|Proteobacteria,1RPNP@1236|Gammaproteobacteria,1XUAG@135623|Vibrionales 135623|Vibrionales P COG2059 Chromate transport protein ChrA - - - ko:K07240 - - - - ko00000,ko02000 2.A.51.1 - - Chromate_transp k141_12887_10 223926.28807404 8.23e-184 515.0 COG0583@1|root,COG0583@2|Bacteria,1QSDA@1224|Proteobacteria,1RZU9@1236|Gammaproteobacteria,1XTD6@135623|Vibrionales 135623|Vibrionales K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_9325_1 1116375.VEJY3_19986 5.6e-302 842.0 COG2267@1|root,COG2267@2|Bacteria,1QUH9@1224|Proteobacteria,1T1YS@1236|Gammaproteobacteria,1XU7S@135623|Vibrionales 135623|Vibrionales I Bacterial virulence factor lipase N-terminal - GO:0003674,GO:0003824,GO:0006629,GO:0008150,GO:0008152,GO:0009056,GO:0016042,GO:0016298,GO:0016787,GO:0016788,GO:0044238,GO:0071704,GO:1901575 - - - - - - - - - - Lipase_bact_N k141_23666_2 1042377.AFPJ01000007_gene1794 4.89e-93 282.0 COG0429@1|root,COG0429@2|Bacteria,1MWV1@1224|Proteobacteria,1RN39@1236|Gammaproteobacteria,46554@72275|Alteromonadaceae 1236|Gammaproteobacteria S hydrolase of the alpha beta-hydrolase fold yheT GO:0003674,GO:0003824,GO:0006629,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0044237,GO:0044238,GO:0044255,GO:0050526,GO:0052689,GO:0071704 - ko:K07019 - - - - ko00000 - - - Abhydrolase_1 k141_973_1 1453501.JELR01000001_gene2590 1.44e-97 298.0 COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,1S2IK@1236|Gammaproteobacteria,466ZA@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - - - - - - - - - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 k141_25967_1 218284.CCDN010000005_gene3488 1.49e-171 484.0 COG0524@1|root,COG0524@2|Bacteria,1TPGM@1239|Firmicutes,4HD0H@91061|Bacilli,1ZASN@1386|Bacillus 91061|Bacilli G Belongs to the carbohydrate kinase PfkB family - - 2.7.1.4 ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 - R00760,R00867,R03920 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB k141_22320_1 218284.CCDN010000004_gene3151 1.79e-238 662.0 COG0189@1|root,COG0189@2|Bacteria,1TSWS@1239|Firmicutes,4HCJA@91061|Bacilli,1ZAR6@1386|Bacillus 91061|Bacilli HJ YheC/D like ATP-grasp yheD GO:0005575,GO:0005623,GO:0042601,GO:0042763,GO:0044464 - - - - - - - - - - ATPgrasp_YheCD k141_10434_1 457570.Nther_0985 4.21e-17 86.7 COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia 186801|Clostridia T Histidine kinase phoR - 2.7.13.3 ko:K07636 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,sCache_like k141_30344_2 545693.BMQ_5080 1.46e-111 347.0 COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,4HAW9@91061|Bacilli,1ZARC@1386|Bacillus 91061|Bacilli L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate uvrA - - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran k141_3161_2 930166.CD58_29280 1.97e-36 127.0 COG0446@1|root,COG0446@2|Bacteria,1NR3M@1224|Proteobacteria,1RQ07@1236|Gammaproteobacteria 1236|Gammaproteobacteria C One of at least two accessory proteins for anaerobic nitric oxide (NO) reductase. Reduces the rubredoxin moiety of NO reductase rubB - 1.18.1.1 ko:K05297,ko:K12265 ko00071,ko05132,map00071,map05132 - R02000 - ko00000,ko00001,ko01000 - - - Pyr_redox_2,Rubredoxin k141_16275_1 1395571.TMS3_0111135 2.13e-162 462.0 COG0604@1|root,COG0604@2|Bacteria,1MXCV@1224|Proteobacteria,1S13Q@1236|Gammaproteobacteria 1236|Gammaproteobacteria C NADPH quinone reductase and related Zn-dependent - - 1.6.5.5 ko:K00344 - - - - ko00000,ko01000 - - - ADH_N,ADH_zinc_N k141_16275_2 1453501.JELR01000001_gene2507 5.34e-35 122.0 COG5642@1|root,COG5642@2|Bacteria,1N2DF@1224|Proteobacteria,1S93Q@1236|Gammaproteobacteria,4689N@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF2384) - - - - - - - - - - - - DUF2384,HTH_3 k141_29342_1 1279017.AQYJ01000028_gene2040 5.29e-86 265.0 2DBVC@1|root,2ZBAF@2|Bacteria,1PT3T@1224|Proteobacteria,1RZJK@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Psort location CytoplasmicMembrane, score 9.46 - - - - - - - - - - - - - k141_29342_2 1042377.AFPJ01000028_gene2190 5.79e-178 505.0 COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,1RN5Z@1236|Gammaproteobacteria,46525@72275|Alteromonadaceae 1236|Gammaproteobacteria S permease VP2476 - - - - - - - - - - - AI-2E_transport k141_29342_3 1453501.JELR01000002_gene1301 4.77e-115 336.0 COG3108@1|root,COG3108@2|Bacteria,1NDQH@1224|Proteobacteria,1T130@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Peptidase M15 - - - - - - - - - - - - Peptidase_M15_3 k141_35441_2 1217718.ALOU01000047_gene3803 3.1e-10 60.8 COG5361@1|root,COG5361@2|Bacteria,1MWTW@1224|Proteobacteria,2VPV5@28216|Betaproteobacteria,1K3I9@119060|Burkholderiaceae 28216|Betaproteobacteria S Protein of unknown function (DUF1214) - - - - - - - - - - - - DUF1214,DUF1254 k141_22348_1 218284.CCDN010000007_gene3787 2.03e-294 814.0 COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,4H9Y6@91061|Bacilli,1ZBFI@1386|Bacillus 91061|Bacilli L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrB GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.3 ko:K02470 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim k141_23694_1 1042377.AFPJ01000019_gene2546 2.49e-140 424.0 COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,1RN05@1236|Gammaproteobacteria,464MR@72275|Alteromonadaceae 1236|Gammaproteobacteria S Insulinase (Peptidase family M16) ptrA - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C k141_34180_1 1408424.JHYI01000011_gene1400 1.35e-57 193.0 COG0697@1|root,COG0697@2|Bacteria,1V23Q@1239|Firmicutes,4HDPS@91061|Bacilli,1ZEXG@1386|Bacillus 91061|Bacilli EG EamA-like transporter family - - - - - - - - - - - - EamA k141_15056_1 218284.CCDN010000007_gene3840 8.17e-109 315.0 2B3H9@1|root,345WB@2|Bacteria,1W0M6@1239|Firmicutes,4HYK2@91061|Bacilli,1ZFP0@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_1004_1 42565.FP66_01345 4.8e-119 351.0 COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,1RMSF@1236|Gammaproteobacteria,1XING@135619|Oceanospirillales 135619|Oceanospirillales S GTPase that plays an essential role in the late steps of ribosome biogenesis der - - ko:K03977 - - - - ko00000,ko03009 - - - KH_dom-like,MMR_HSR1 k141_35442_1 1116375.VEJY3_17716 1.2e-72 233.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XSE1@135623|Vibrionales 135623|Vibrionales T COG2202 FOG PAS PAC domain - - - ko:K03406,ko:K03776 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - MCPsignal,PAS_3 k141_7952_1 1042377.AFPJ01000036_gene1194 7.56e-75 231.0 COG0780@1|root,COG2904@1|root,COG0780@2|Bacteria,COG2904@2|Bacteria,1MW0M@1224|Proteobacteria,1RNXM@1236|Gammaproteobacteria,4650F@72275|Alteromonadaceae 1236|Gammaproteobacteria S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) queF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016651,GO:0016657,GO:0018130,GO:0019438,GO:0033739,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.7.1.13 ko:K06879,ko:K09457 ko00790,ko01100,map00790,map01100 - R07605 RC01875 ko00000,ko00001,ko01000,ko03016 - - iSFV_1184.SFV_2663,iSF_1195.SF2807,iS_1188.S3002 QueF,QueF_N k141_5728_2 1279017.AQYJ01000027_gene1979 6.53e-23 97.1 COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,1RMBT@1236|Gammaproteobacteria,4642P@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG1194 A G-specific DNA glycosylase mutY GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - ko:K03575 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD,NUDIX_4 k141_10445_1 234267.Acid_3593 7.9e-52 188.0 COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y3FE@57723|Acidobacteria 2|Bacteria KU WD40 domain protein beta Propeller - - 2.7.11.1 ko:K08884,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PD40,Pkinase,WD40 k141_3178_1 1211814.CAPG01000071_gene3351 4.71e-68 214.0 COG0785@1|root,COG0785@2|Bacteria,1TQH1@1239|Firmicutes,4H9UJ@91061|Bacilli,1ZBPX@1386|Bacillus 91061|Bacilli O cytochrome c biogenesis protein ccdA - - ko:K06196 - - - - ko00000,ko02000 5.A.1.2 - - DsbD k141_25997_1 1453501.JELR01000002_gene511 1.57e-170 490.0 COG2133@1|root,COG2133@2|Bacteria,1MVK5@1224|Proteobacteria,1RPE8@1236|Gammaproteobacteria,4665U@72275|Alteromonadaceae 1236|Gammaproteobacteria G COG2133 Glucose sorbosone dehydrogenases - - - - - - - - - - - - GSDH k141_25997_3 1453501.JELR01000002_gene517 3.16e-35 129.0 COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,1RMKY@1236|Gammaproteobacteria,464WM@72275|Alteromonadaceae 1236|Gammaproteobacteria H Belongs to the FPP GGPP synthase family ispA GO:0003674,GO:0003824,GO:0004161,GO:0004337,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016114,GO:0016740,GO:0016765,GO:0019637,GO:0033383,GO:0033384,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0045337,GO:0045338,GO:0071704,GO:0090407,GO:1901576 2.5.1.1,2.5.1.10,2.5.1.29 ko:K00795,ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00366 R01658,R02003,R02061 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 - - iPC815.YPO3176,iSFV_1184.SFV_0386 polyprenyl_synt k141_22351_1 1196031.ALEG01000028_gene4245 1.6e-78 240.0 COG0561@1|root,COG0561@2|Bacteria,1TSZZ@1239|Firmicutes,4HB54@91061|Bacilli,1ZAT7@1386|Bacillus 91061|Bacilli S HAD family hydrolase - - 5.2.1.8 ko:K03768 - - - - ko00000,ko01000,ko03110 - - - Hydrolase_3,PRA-PH k141_11721_1 948106.AWZT01000015_gene679 1.96e-71 231.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2VHGR@28216|Betaproteobacteria,1K02G@119060|Burkholderiaceae 28216|Betaproteobacteria C belongs to the aldehyde dehydrogenase family gabD - 1.2.1.16,1.2.1.20,1.2.1.79 ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 M00027 R00713,R00714,R02401 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_27991_1 218284.CCDN010000001_gene1494 1.32e-160 455.0 COG1125@1|root,COG1125@2|Bacteria,1TPV8@1239|Firmicutes,4H9SI@91061|Bacilli,1ZBIG@1386|Bacillus 91061|Bacilli E COG1125 ABC-type proline glycine betaine transport systems, ATPase components - - - ko:K05847 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - ABC_tran,CBS k141_27991_2 218284.CCDN010000001_gene1493 7.72e-29 108.0 COG1174@1|root,COG1174@2|Bacteria,1UHWH@1239|Firmicutes,4ISE5@91061|Bacilli,1ZS6F@1386|Bacillus 91061|Bacilli E Binding-protein-dependent transport system inner membrane component - - - ko:K05846 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - BPD_transp_1 k141_6945_1 935836.JAEL01000082_gene1043 1.62e-89 279.0 COG1966@1|root,COG1966@2|Bacteria,1TQN8@1239|Firmicutes,4H9SU@91061|Bacilli,1ZC6K@1386|Bacillus 91061|Bacilli T Carbon starvation protein cstA GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007154,GO:0008150,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031667,GO:0031668,GO:0031669,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:0071944 - ko:K06200 - - - - ko00000 - - - CstA,CstA_5TM k141_32886_1 1267535.KB906767_gene3036 1.96e-16 80.5 COG0673@1|root,COG0673@2|Bacteria,3Y3ET@57723|Acidobacteria,2JHRR@204432|Acidobacteriia 204432|Acidobacteriia S Oxidoreductase family, NAD-binding Rossmann fold - - - - - - - - - - - - GFO_IDH_MocA k141_32886_2 671143.DAMO_1214 8.13e-36 129.0 COG0005@1|root,COG0005@2|Bacteria,2NNYQ@2323|unclassified Bacteria 2|Bacteria F Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates mtnP GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004731,GO:0006082,GO:0006139,GO:0006144,GO:0006168,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009112,GO:0009113,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0017061,GO:0017144,GO:0018130,GO:0019438,GO:0019509,GO:0019752,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.28 ko:K00772 ko00270,ko01100,map00270,map01100 M00034 R01402 RC00063,RC02819 ko00000,ko00001,ko00002,ko01000 - - iAF987.Gmet_2684 PNP_UDP_1 k141_34181_1 1294265.JCM21738_524 1.73e-143 414.0 COG0477@1|root,COG2814@2|Bacteria,1TSS7@1239|Firmicutes,4HC6A@91061|Bacilli,1ZBCF@1386|Bacillus 91061|Bacilli EGP Transmembrane secretion effector - - - - - - - - - - - - MFS_1 k141_15058_1 908612.HMPREF9720_1069 8.67e-55 192.0 COG3808@1|root,COG3808@2|Bacteria,4NF2I@976|Bacteroidetes,2FM7F@200643|Bacteroidia,22V18@171550|Rikenellaceae 976|Bacteroidetes C Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane hppA - 3.6.1.1 ko:K15987 ko00190,map00190 - - - ko00000,ko00001,ko01000 3.A.10.1 - - H_PPase,OmpA k141_4372_1 265729.GS18_0214575 2.31e-55 191.0 COG1165@1|root,COG1165@2|Bacteria,1TRDB@1239|Firmicutes,4HC48@91061|Bacilli,1ZANU@1386|Bacillus 91061|Bacilli H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) menD - 2.2.1.9 ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R08165 RC02186 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS05085 TPP_enzyme_C,TPP_enzyme_M_2,TPP_enzyme_N k141_28235_2 1347087.CBYO010000020_gene3043 2.43e-28 109.0 COG1595@1|root,COG1595@2|Bacteria,1V8BF@1239|Firmicutes,4HJ64@91061|Bacilli 91061|Bacilli K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_37823_1 1453501.JELR01000005_gene1574 1.84e-178 507.0 COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,1RM9E@1236|Gammaproteobacteria,4655Q@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the ABC transporter superfamily ugpC - - ko:K10112,ko:K10195 ko02010,map02010 M00194,M00196,M00197,M00200,M00201,M00202,M00206,M00207,M00491,M00602,M00605,M00606 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.11 - - ABC_tran,TOBE_2 k141_37823_2 1453501.JELR01000005_gene1575 0.0 887.0 COG1175@1|root,COG2182@1|root,COG1175@2|Bacteria,COG2182@2|Bacteria,1MXKR@1224|Proteobacteria,1RN6B@1236|Gammaproteobacteria,46801@72275|Alteromonadaceae 1236|Gammaproteobacteria G COG1175 ABC-type sugar transport systems, permease components malF GO:0003674,GO:0003824,GO:0005215,GO:0005363,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006950,GO:0006974,GO:0008150,GO:0008643,GO:0009987,GO:0015144,GO:0015154,GO:0015157,GO:0015399,GO:0015405,GO:0015422,GO:0015423,GO:0015766,GO:0015768,GO:0015772,GO:0015774,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0033037,GO:0033554,GO:0034219,GO:0042623,GO:0042626,GO:0042956,GO:0043190,GO:0043211,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990060,GO:1990351 - ko:K10109,ko:K15771 ko02010,map02010 M00194,M00491 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.1,3.A.1.1.16,3.A.1.1.2,3.A.1.1.22 - iZ_1308.Z5631 BPD_transp_1,MalF_P2 k141_30527_1 883126.HMPREF9710_04754 7.25e-09 60.5 COG0300@1|root,COG0300@2|Bacteria,1R3VU@1224|Proteobacteria,2VN1U@28216|Betaproteobacteria,477GS@75682|Oxalobacteraceae 28216|Betaproteobacteria S KR domain - - - - - - - - - - - - adh_short k141_29719_6 1116375.VEJY3_21926 9.52e-191 532.0 COG0109@1|root,COG0109@2|Bacteria,1MW3S@1224|Proteobacteria,1RNHC@1236|Gammaproteobacteria,1XUYC@135623|Vibrionales 135623|Vibrionales O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group cyoE - 2.5.1.141 ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 M00154 R07411 RC01786 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 - - - UbiA k141_29719_7 1116375.VEJY3_21921 6.62e-108 311.0 COG0545@1|root,COG0545@2|Bacteria,1RCWV@1224|Proteobacteria,1S7UP@1236|Gammaproteobacteria,1XWX0@135623|Vibrionales 135623|Vibrionales O COG0545 FKBP-type peptidyl-prolyl cis-trans isomerases 1 - - 5.2.1.8 ko:K01802 - - - - ko00000,ko01000 - - - FKBP_C,FKBP_N k141_28271_2 218284.CCDN010000001_gene646 8.51e-157 449.0 COG0510@1|root,COG0510@2|Bacteria,1VB8C@1239|Firmicutes,4HNC9@91061|Bacilli,1ZAQ0@1386|Bacillus 91061|Bacilli M choline kinase involved in LPS biosynthesis - - - - - - - - - - - - APH k141_34430_1 1279017.AQYJ01000027_gene1807 2.73e-259 719.0 COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,1RN5S@1236|Gammaproteobacteria,46440@72275|Alteromonadaceae 1236|Gammaproteobacteria J Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 mnmE GO:0000166,GO:0001510,GO:0001882,GO:0001883,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006457,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009268,GO:0009451,GO:0009628,GO:0009636,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0030488,GO:0030955,GO:0031420,GO:0032259,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0061077,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 - ko:K03650 - - R08701 RC00053,RC00209,RC00870 ko00000,ko01000,ko03016 - - - MMR_HSR1,MnmE_helical,TrmE_N k141_34430_2 1279017.AQYJ01000027_gene1806 7.34e-315 867.0 COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,1RMH1@1236|Gammaproteobacteria,46553@72275|Alteromonadaceae 1236|Gammaproteobacteria U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins yidC GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0031224,GO:0031226,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051205,GO:0051234,GO:0051259,GO:0051260,GO:0051641,GO:0061024,GO:0065003,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150 - ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 - - 60KD_IMP,YidC_periplas k141_34430_3 498211.CJA_3824 2.77e-40 134.0 COG0759@1|root,COG0759@2|Bacteria,1N6U4@1224|Proteobacteria,1SCG6@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Could be involved in insertion of integral membrane proteins into the membrane yidD GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0031224,GO:0031226,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150 - ko:K08998 - - - - ko00000 - - - Haemolytic k141_34430_4 1134474.O59_000507 4.64e-32 119.0 COG0594@1|root,COG0594@2|Bacteria,1MZQE@1224|Proteobacteria,1S90M@1236|Gammaproteobacteria,1FHHA@10|Cellvibrio 1236|Gammaproteobacteria J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme rnpA GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031974,GO:0031981,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 ko:K03536 - - - - ko00000,ko01000,ko03016 - - - Ribonuclease_P k141_4621_1 218284.CCDN010000004_gene3085 3.33e-71 216.0 29RAQ@1|root,30CCF@2|Bacteria,1U9MH@1239|Firmicutes,4IJSY@91061|Bacilli,1ZG4U@1386|Bacillus 91061|Bacilli S Family of unknown function (DUF5365) yhcU - - - - - - - - - - - DUF5365 k141_36555_1 1042377.AFPJ01000019_gene2498 2.86e-101 308.0 COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,1RMFY@1236|Gammaproteobacteria,464BF@72275|Alteromonadaceae 1236|Gammaproteobacteria J thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence rpsA GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113,GO:2000765,GO:2000766 - ko:K02945 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - S1 k141_28272_1 218284.CCDN010000001_gene1245 1.04e-75 233.0 COG2324@1|root,COG2324@2|Bacteria,1V4BB@1239|Firmicutes,4HI6A@91061|Bacilli,1ZFZJ@1386|Bacillus 91061|Bacilli S Carotenoid biosynthesis protein - - - - - - - - - - - - Caroten_synth k141_10662_2 218284.CCDN010000008_gene4209 1.46e-75 230.0 2DMXQ@1|root,32UHX@2|Bacteria,1VD2A@1239|Firmicutes,4HKUA@91061|Bacilli,1ZJEN@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_10662_3 218284.CCDN010000008_gene4210 4.74e-13 68.2 COG3641@1|root,COG3641@2|Bacteria,1TS5F@1239|Firmicutes,4HC7U@91061|Bacilli,1ZCS4@1386|Bacillus 91061|Bacilli S Phosphotransferase system, EIIC - - - ko:K07035 - - - - ko00000 - - - PTS_EIIC_2 k141_29720_1 218284.CCDN010000001_gene1907 1.43e-49 160.0 COG0835@1|root,COG0835@2|Bacteria,1V4HH@1239|Firmicutes,4HHB5@91061|Bacilli,1ZGZE@1386|Bacillus 91061|Bacilli NT COG0835 Chemotaxis signal transduction protein cheW GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006935,GO:0008150,GO:0009453,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0042333,GO:0044424,GO:0044444,GO:0044464,GO:0050896 - ko:K03408 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - CheW k141_29720_2 1034347.CAHJ01000010_gene2054 1.08e-62 209.0 COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1TPMS@1239|Firmicutes,4HAQD@91061|Bacilli,1ZATW@1386|Bacillus 91061|Bacilli NT COG0643 Chemotaxis protein histidine kinase and related kinases cheA - 2.7.13.3 ko:K03407 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt,P2 k141_21228_1 1279017.AQYJ01000029_gene3782 5.81e-112 325.0 COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,1S26C@1236|Gammaproteobacteria,466N6@72275|Alteromonadaceae 1236|Gammaproteobacteria F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis tmk GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 ko:K00943 ko00240,ko01100,map00240,map01100 M00053 R02094,R02098 RC00002 ko00000,ko00001,ko00002,ko01000 - - iECABU_c1320.ECABU_c13120,ic_1306.c1370 Thymidylate_kin k141_21228_2 1279017.AQYJ01000029_gene3783 5.21e-75 233.0 COG0470@1|root,COG0470@2|Bacteria,1MY1W@1224|Proteobacteria,1RNYA@1236|Gammaproteobacteria,466TQ@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG0470 ATPase involved in DNA replication holB GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNApol3-delta_C k141_4622_1 1294265.JCM21738_381 1.12e-44 154.0 COG1744@1|root,COG1744@2|Bacteria,1TPEU@1239|Firmicutes,4HANH@91061|Bacilli,1ZBS3@1386|Bacillus 91061|Bacilli S ABC-type transport system, periplasmic component surface lipoprotein yufN - - ko:K07335 - - - - ko00000 - - - Bmp k141_8074_1 1453501.JELR01000001_gene2230 7.96e-87 266.0 COG0470@1|root,COG0470@2|Bacteria,1MY1W@1224|Proteobacteria,1RNYA@1236|Gammaproteobacteria,466TQ@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG0470 ATPase involved in DNA replication holB GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNApol3-delta_C k141_28273_1 1453501.JELR01000002_gene890 1.88e-65 224.0 COG1652@1|root,COG3210@1|root,COG1652@2|Bacteria,COG3210@2|Bacteria,1MXIP@1224|Proteobacteria,1RSAX@1236|Gammaproteobacteria,468YR@72275|Alteromonadaceae 1236|Gammaproteobacteria U haemagglutination activity domain Z012_01725 GO:0005575,GO:0005576 - - - - - - - - - - ESPR,Glug,Haemagg_act k141_10663_1 1453501.JELR01000002_gene115 2.1e-100 319.0 COG0587@1|root,COG0587@2|Bacteria,1MUE4@1224|Proteobacteria,1RQA8@1236|Gammaproteobacteria,464B5@72275|Alteromonadaceae 1236|Gammaproteobacteria L DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase dnaE2 GO:0003674,GO:0003824,GO:0003887,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K14162 - - - - ko00000,ko01000,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon k141_21229_1 218284.CCDN010000007_gene3964 6.47e-121 353.0 COG1879@1|root,COG1879@2|Bacteria,1TSUI@1239|Firmicutes,4HBMV@91061|Bacilli,1ZC6R@1386|Bacillus 91061|Bacilli G Periplasmic binding protein domain rbsB5 - - ko:K02058 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - Peripla_BP_4 k141_17731_1 1453501.JELR01000001_gene1816 1.77e-172 488.0 COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,1RPQ7@1236|Gammaproteobacteria,464Z9@72275|Alteromonadaceae 1236|Gammaproteobacteria I Glycerol-3-phosphate dehydrogenase gpsA GO:0003674,GO:0003824,GO:0004367,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006072,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0047952,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 - R00842,R00844 RC00029 ko00000,ko00001,ko01000 - - iJN746.PP_4169,iSFV_1184.SFV_3923 NAD_Gly3P_dh_C,NAD_Gly3P_dh_N k141_31709_1 574375.BAGA_18825 6.7e-88 284.0 COG4926@1|root,COG4926@2|Bacteria,1TQHW@1239|Firmicutes,4HFA8@91061|Bacilli,1ZPV9@1386|Bacillus 91061|Bacilli S Prophage endopeptidase tail - - - - - - - - - - - - Prophage_tail k141_8075_2 218284.CCDN010000001_gene1930 5.11e-33 123.0 COG1317@1|root,COG1317@2|Bacteria,1V1H3@1239|Firmicutes,4IS1Y@91061|Bacilli,1ZS0H@1386|Bacillus 91061|Bacilli NU Flagellar assembly protein FliH fliH - - ko:K02411 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - FliH k141_4624_1 1168067.JAGP01000001_gene1013 1.92e-14 78.6 COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,1RPCB@1236|Gammaproteobacteria,4605Q@72273|Thiotrichales 72273|Thiotrichales O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner lon - 3.4.21.53 ko:K01338 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - AAA,LON_substr_bdg,Lon_C k141_21230_1 1279017.AQYJ01000027_gene1788 1.91e-102 318.0 COG4772@1|root,COG4772@2|Bacteria,1MWDG@1224|Proteobacteria,1RQA5@1236|Gammaproteobacteria,464IF@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG4772 Outer membrane receptor for Fe3 -dicitrate fecA - - ko:K16091 - - - - ko00000,ko02000 1.B.14.1.14 - - Plug,TonB_dep_Rec k141_30553_1 1190606.AJYG01000007_gene2472 1.41e-63 208.0 COG0583@1|root,COG0583@2|Bacteria,1MW1R@1224|Proteobacteria,1RQMP@1236|Gammaproteobacteria,1XUU4@135623|Vibrionales 135623|Vibrionales K Transcriptional regulator, LysR family - - - - - - - - - - - - HTH_1,LysR_substrate k141_29722_1 218284.CCDN010000001_gene1450 1.73e-120 354.0 COG0665@1|root,COG0665@2|Bacteria,1VTRW@1239|Firmicutes,4HD2K@91061|Bacilli,1ZCZM@1386|Bacillus 91061|Bacilli E Glycine oxidase thiO GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016043,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0022607,GO:0034641,GO:0036094,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043436,GO:0043799,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0072527,GO:0072528,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.4.3.19 ko:K03153 ko00730,ko01100,map00730,map01100 - R07463 RC01788 ko00000,ko00001,ko01000 - - - DAO k141_29722_2 218284.CCDN010000001_gene1451 2.14e-11 58.9 COG2104@1|root,COG2104@2|Bacteria 2|Bacteria H thiamine diphosphate biosynthetic process thiS - - ko:K03154 ko04122,map04122 - - - ko00000,ko00001 - - iJN678.ycf40 ThiS k141_17732_3 218284.CCDN010000001_gene1101 1.8e-46 160.0 COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,4HAJ6@91061|Bacilli,1ZAUP@1386|Bacillus 91061|Bacilli S GTPase that plays an essential role in the late steps of ribosome biogenesis der - - ko:K03977 - - - - ko00000,ko03009 - - - KH_dom-like,MMR_HSR1 k141_21231_1 1340434.AXVA01000008_gene3651 9.4e-97 288.0 COG1524@1|root,COG1524@2|Bacteria,1TR0T@1239|Firmicutes,4HD1Y@91061|Bacilli,1ZIIG@1386|Bacillus 91061|Bacilli S Type I phosphodiesterase / nucleotide pyrophosphatase - - - - - - - - - - - - Phosphodiest k141_3444_1 357808.RoseRS_2884 1.22e-18 85.1 COG2115@1|root,COG2115@2|Bacteria,2G688@200795|Chloroflexi,376KP@32061|Chloroflexia 32061|Chloroflexia G PFAM Xylose isomerase domain protein TIM barrel xylA - 5.3.1.5 ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 - R00878,R01432 RC00376,RC00516 ko00000,ko00001,ko01000 - - - AP_endonuc_2 k141_3444_2 1304880.JAGB01000003_gene1303 3.84e-21 94.4 COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1TPYV@1239|Firmicutes,248JB@186801|Clostridia 186801|Clostridia E MeTHIonine synthase metH - 2.1.1.13 ko:K00548 ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230 M00017 R00946,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - B12-binding,B12-binding_2,Pterin_bind,S-methyl_trans k141_8076_1 1122137.AQXF01000004_gene1726 2.95e-80 252.0 COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,2TTYC@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q COG1228 Imidazolonepropionase and related amidohydrolases - - - - - - - - - - - - Amidohydro_1 k141_28275_2 1042377.AFPJ01000007_gene1928 6.83e-06 47.4 COG2902@1|root,COG2902@2|Bacteria,1MXNV@1224|Proteobacteria,1RQVZ@1236|Gammaproteobacteria,464UW@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG2902 NAD-specific glutamate dehydrogenase gdhB - 1.4.1.2 ko:K15371 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 - R00243 RC00006,RC02799 ko00000,ko00001,ko01000 - - - Bac_GDH,GDH_N k141_29723_1 1385514.N782_11315 7.69e-135 404.0 COG4412@1|root,COG4412@2|Bacteria,1TQYP@1239|Firmicutes,4HD82@91061|Bacilli,2YA1P@289201|Pontibacillus 91061|Bacilli S protease - - - ko:K09607 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M6 k141_2227_1 1085623.GNIT_0282 6.85e-116 365.0 COG1506@1|root,COG1506@2|Bacteria,1MUJ3@1224|Proteobacteria,1RPAW@1236|Gammaproteobacteria,46468@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases - - - - - - - - - - - - Peptidase_S9 k141_2227_2 1453501.JELR01000005_gene1566 2.62e-66 220.0 COG4773@1|root,COG4773@2|Bacteria,1QTXJ@1224|Proteobacteria,1T2BS@1236|Gammaproteobacteria,46D8F@72275|Alteromonadaceae 1236|Gammaproteobacteria P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec k141_33162_1 997346.HMPREF9374_0182 6.25e-41 142.0 COG1670@1|root,COG1670@2|Bacteria,1V8EU@1239|Firmicutes,4HJPX@91061|Bacilli 91061|Bacilli J Acetyltransferases, including N-acetylases of ribosomal proteins - - - - - - - - - - - - Acetyltransf_3 k141_10665_2 1347369.CCAD010000052_gene103 6.09e-24 92.4 COG4483@1|root,COG4483@2|Bacteria,1VK83@1239|Firmicutes,4HRG2@91061|Bacilli,1ZISV@1386|Bacillus 91061|Bacilli S protein conserved in bacteria yqgQ - - - - - - - - - - - DUF910 k141_36557_1 1453501.JELR01000001_gene3259 1.11e-127 392.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,464R3@72275|Alteromonadaceae 1236|Gammaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K18989 - M00720 - - ko00000,ko00002,ko02000 2.A.6.2.30 - - ACR_tran k141_31711_1 997296.PB1_06697 2.34e-147 447.0 COG0085@1|root,COG0085@2|Bacteria,1TP96@1239|Firmicutes,4H9PK@91061|Bacilli,1ZBPC@1386|Bacillus 91061|Bacilli K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoB GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 k141_17734_1 218284.CCDN010000001_gene1352 2.83e-101 303.0 COG0531@1|root,COG0531@2|Bacteria,1UIWG@1239|Firmicutes,4ISUQ@91061|Bacilli,1ZS6D@1386|Bacillus 91061|Bacilli E Spore germination protein - - - - - - - - - - - - Spore_permease k141_4627_1 218284.CCDN010000004_gene3041 1.04e-108 320.0 COG4294@1|root,COG4294@2|Bacteria,1TTCB@1239|Firmicutes,4H9PY@91061|Bacilli,1ZCJ7@1386|Bacillus 91061|Bacilli L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion uvsE - - ko:K13281 - - - - ko00000,ko01000 - - - UvdE k141_37857_1 1116375.VEJY3_11285 1.15e-147 475.0 COG3170@1|root,COG3170@2|Bacteria,1MXV7@1224|Proteobacteria,1RMM5@1236|Gammaproteobacteria,1XUV6@135623|Vibrionales 135623|Vibrionales NU COG3170 Tfp pilus assembly protein FimV - - - ko:K08086 - - - - ko00000 - - - - k141_37857_2 1116375.VEJY3_11280 2.07e-191 531.0 COG0101@1|root,COG0101@2|Bacteria,1MUYI@1224|Proteobacteria,1RMK2@1236|Gammaproteobacteria,1XTDP@135623|Vibrionales 135623|Vibrionales J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs truA GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 ko:K06173 - - - - ko00000,ko01000,ko03016 - - - PseudoU_synth_1 k141_37857_3 674977.VMC_15480 1.19e-79 243.0 COG0777@1|root,COG0777@2|Bacteria,1MW8G@1224|Proteobacteria,1RNDS@1236|Gammaproteobacteria,1XUF4@135623|Vibrionales 135623|Vibrionales I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA accD GO:0003674,GO:0003824,GO:0003989,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009317,GO:0009987,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0019752,GO:0032787,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576,GO:1902494 2.1.3.15,6.4.1.2 ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans k141_36558_1 1453501.JELR01000002_gene1049 5.87e-63 210.0 COG2234@1|root,COG2234@2|Bacteria,1MUZ7@1224|Proteobacteria,1RS0Q@1236|Gammaproteobacteria,4653N@72275|Alteromonadaceae 1236|Gammaproteobacteria S PA domain - - - - - - - - - - - - PA,Peptidase_M28 k141_10666_1 218284.CCDN010000001_gene67 3.68e-135 408.0 COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,4HAWB@91061|Bacilli,1ZAQK@1386|Bacillus 91061|Bacilli J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS - 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1,zf-FPG_IleRS k141_31712_1 1453501.JELR01000002_gene907 6.42e-102 325.0 COG3523@1|root,COG3523@2|Bacteria,1MV3D@1224|Proteobacteria,1RPQ2@1236|Gammaproteobacteria,464BZ@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria icmF - - ko:K11891 ko02025,ko03070,map02025,map03070 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - IcmF-related,IcmF_C,ImcF-related_N k141_17735_1 1340434.AXVA01000005_gene4675 7.71e-104 311.0 COG0124@1|root,COG0124@2|Bacteria,1TP3D@1239|Firmicutes,4HAM2@91061|Bacilli,1ZBXR@1386|Bacillus 91061|Bacilli J histidyl-tRNA synthetase hisS - 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_2b,tRNA-synt_His k141_4628_1 357808.RoseRS_4104 1.31e-34 130.0 COG0683@1|root,COG0683@2|Bacteria,2G904@200795|Chloroflexi,3754R@32061|Chloroflexia 32061|Chloroflexia E Periplasmic binding protein domain - - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 k141_21232_1 223926.28809424 1.9e-239 662.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RM93@1236|Gammaproteobacteria,1Y072@135623|Vibrionales 135623|Vibrionales I Thiolase, C-terminal domain - - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N k141_28276_1 218284.CCDN010000001_gene1764 3.81e-181 526.0 COG3276@1|root,COG3276@2|Bacteria,1TPQS@1239|Firmicutes,4HDD5@91061|Bacilli,1ZD2K@1386|Bacillus 91061|Bacilli J Selenocysteine-specific translation elongation factor selB - - ko:K03833 - - - - ko00000,ko03012 - - - GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3 k141_33164_1 1229485.AMYV01000005_gene4440 2.83e-50 167.0 COG4126@1|root,COG4126@2|Bacteria 2|Bacteria E flavin adenine dinucleotide binding hyuE - 5.1.99.3 ko:K16841 ko00230,ko01120,map00230,map01120 - R03925 RC01027 ko00000,ko00001,ko01000 - - - Asp_Glu_race k141_4629_1 1340434.AXVA01000005_gene4850 4.98e-109 329.0 COG4626@1|root,COG4626@2|Bacteria,1TPU1@1239|Firmicutes,4HAXI@91061|Bacilli,1ZE32@1386|Bacillus 91061|Bacilli S Terminase - - - - - - - - - - - - Terminase_1 k141_37858_1 1279017.AQYJ01000029_gene3743 9.51e-13 64.3 COG1553@1|root,COG1553@2|Bacteria,1N021@1224|Proteobacteria,1S99J@1236|Gammaproteobacteria,467M1@72275|Alteromonadaceae 1236|Gammaproteobacteria P conserved protein involved in intracellular sulfur reduction tusD GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0019417,GO:0032991,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055114,GO:0071704,GO:0090304,GO:0097163,GO:0140104,GO:1901360,GO:1902494,GO:1990228,GO:1990234 - ko:K07235 ko04122,map04122 - - - ko00000,ko00001,ko01000,ko03016 - - - DrsE k141_37858_3 1453501.JELR01000001_gene2212 2.43e-09 58.5 COG3568@1|root,COG3568@2|Bacteria,1R977@1224|Proteobacteria,1RTF2@1236|Gammaproteobacteria,466AF@72275|Alteromonadaceae 1236|Gammaproteobacteria L Type I phosphodiesterase / nucleotide pyrophosphatase - - - - - - - - - - - - Exo_endo_phos,Phosphodiest k141_2229_1 666686.B1NLA3E_05020 2.6e-132 390.0 COG0677@1|root,COG0677@2|Bacteria,1TPXY@1239|Firmicutes,4HAFY@91061|Bacilli,1ZC93@1386|Bacillus 91061|Bacilli M Belongs to the UDP-glucose GDP-mannose dehydrogenase family - - 1.1.1.136 ko:K13015 ko00520,map00520 - R00421 RC00291 ko00000,ko00001,ko01000,ko01005 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N k141_10667_1 1492922.GY26_14695 2.87e-37 129.0 COG1188@1|root,COG1188@2|Bacteria,1MZR6@1224|Proteobacteria,1S8VU@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Belongs to the HSP15 family hslR GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003727,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009451,GO:0009628,GO:0009987,GO:0016070,GO:0033554,GO:0034605,GO:0034641,GO:0043021,GO:0043023,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - ko:K04762 - - - - ko00000,ko03110 - - - S4 k141_10667_2 1279017.AQYJ01000028_gene2049 9.17e-110 321.0 COG1011@1|root,COG1011@2|Bacteria,1NH15@1224|Proteobacteria,1RP27@1236|Gammaproteobacteria,466G1@72275|Alteromonadaceae 1236|Gammaproteobacteria S Haloacid dehalogenase-like hydrolase yrfG GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008477,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016798,GO:0016799,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050483,GO:0050484 3.1.3.5 ko:K20881 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - HAD_2,Hydrolase k141_10667_3 313606.M23134_00491 4.07e-05 46.2 COG3714@1|root,COG3714@2|Bacteria,4NMZ9@976|Bacteroidetes,47RZ2@768503|Cytophagia 976|Bacteroidetes S PFAM YhhN-like protein - - - - - - - - - - - - YhhN k141_30596_1 42565.FP66_07015 0.0 971.0 COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,1RMWZ@1236|Gammaproteobacteria,1XIHS@135619|Oceanospirillales 135619|Oceanospirillales J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain alaS - 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DHHA1,tRNA-synt_2c,tRNA_SAD k141_37906_1 218284.CCDN010000001_gene24 1.94e-91 297.0 COG1196@1|root,COG1196@2|Bacteria,1TPJV@1239|Firmicutes,4HB89@91061|Bacilli,1ZAWM@1386|Bacillus 91061|Bacilli D Required for chromosome condensation and partitioning smc GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K03529 - - - - ko00000,ko03036 - - - SMC_N,SMC_hinge k141_36593_1 935836.JAEL01000015_gene201 7.27e-114 339.0 COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,4HADT@91061|Bacilli,1ZAZA@1386|Bacillus 91061|Bacilli KT Transcriptional regulator pspF - - - - - - - - - - - CBS,HTH_8,PAS,PAS_9,Sigma54_activat k141_2277_2 218284.CCDN010000001_gene971 1.66e-181 520.0 COG1154@1|root,COG1154@2|Bacteria,1TP37@1239|Firmicutes,4H9QW@91061|Bacilli,1ZBHF@1386|Bacillus 91061|Bacilli H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) dxs - 2.2.1.7 ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 M00096 R05636 RC00032 ko00000,ko00001,ko00002,ko01000 - - - DXP_synthase_N,Transket_pyr,Transketolase_C k141_15287_1 218284.CCDN010000001_gene988 2.62e-84 278.0 COG1404@1|root,COG4412@1|root,COG1404@2|Bacteria,COG4412@2|Bacteria,1TPUY@1239|Firmicutes,4HBDE@91061|Bacilli,1ZDEQ@1386|Bacillus 91061|Bacilli O COG1404 Subtilisin-like serine proteases bpr GO:0005575,GO:0005576 - ko:K13276 - - - - ko00000,ko01000,ko01002,ko03110 - - - CarbopepD_reg_2,CarboxypepD_reg,Inhibitor_I9,Peptidase_M6,Peptidase_S8 k141_34463_1 223926.28807668 5.82e-288 788.0 COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,1RN91@1236|Gammaproteobacteria,1XT5M@135623|Vibrionales 135623|Vibrionales M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine murA GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008760,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R00660 RC00350 ko00000,ko00001,ko01000,ko01011 - - - EPSP_synthase k141_34463_2 223926.28807667 3.95e-164 460.0 COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,1RQYC@1236|Gammaproteobacteria,1XTMX@135623|Vibrionales 135623|Vibrionales I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family plsC - 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase k141_34463_3 55601.VANGNB10_cI2267 4.14e-84 248.0 COG0251@1|root,COG0251@2|Bacteria,1MZ3J@1224|Proteobacteria,1S5XS@1236|Gammaproteobacteria,1XWXC@135623|Vibrionales 135623|Vibrionales J translation initiation inhibitor, yjgF family yjgF - 3.5.99.10 ko:K09022 - - R11098,R11099 RC03275,RC03354 ko00000,ko01000 - - - Ribonuc_L-PSP k141_34463_4 223926.28807665 8.77e-102 295.0 COG1781@1|root,COG1781@2|Bacteria,1RB7J@1224|Proteobacteria,1S2BM@1236|Gammaproteobacteria,1XSYU@135623|Vibrionales 135623|Vibrionales F Involved in allosteric regulation of aspartate carbamoyltransferase pyrI GO:0003674,GO:0003824,GO:0004070,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - ko:K00610 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002 - - - PyrI,PyrI_C k141_34463_5 1116375.VEJY3_13615 5.78e-216 597.0 COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,1RPSV@1236|Gammaproteobacteria,1XTYG@135623|Vibrionales 135623|Vibrionales F Belongs to the ATCase OTCase family pyrB GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N k141_34463_6 1219076.N646_1745 6.16e-235 647.0 COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,1RQ59@1236|Gammaproteobacteria,1XTDM@135623|Vibrionales 135623|Vibrionales E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline argF GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 M00029,M00844 R01398 RC00096 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N k141_34463_7 1116375.VEJY3_13605 1.91e-300 818.0 COG2235@1|root,COG2235@2|Bacteria,1NCGV@1224|Proteobacteria,1RM99@1236|Gammaproteobacteria,1XSY4@135623|Vibrionales 135623|Vibrionales E COG2235 Arginine deiminase arcA GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016813,GO:0016990,GO:0018101,GO:0018193,GO:0018195,GO:0019538,GO:0019752,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044267,GO:0044281,GO:0044282,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.3.6 ko:K01478 ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130 - R00552 RC00177 ko00000,ko00001,ko01000 - - - Amidinotransf k141_34463_8 674977.VMC_18650 2.72e-86 254.0 COG3076@1|root,COG3076@2|Bacteria,1RDKS@1224|Proteobacteria,1S4A6@1236|Gammaproteobacteria,1XWVQ@135623|Vibrionales 135623|Vibrionales S Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome rraB - - ko:K09893 - - - - ko00000,ko03019 - - - RraB k141_34463_9 1116375.VEJY3_13595 2.1e-176 493.0 COG3250@1|root,COG3250@2|Bacteria,1NYBH@1224|Proteobacteria,1RZPC@1236|Gammaproteobacteria,1XSPV@135623|Vibrionales 135623|Vibrionales G COG3250 Beta-galactosidase beta-glucuronidase - - - - - - - - - - - - Glyco_hydro_2_N k141_34463_10 1116375.VEJY3_13590 7.29e-104 301.0 COG1246@1|root,COG1246@2|Bacteria,1QUGE@1224|Proteobacteria,1T1Y6@1236|Gammaproteobacteria,1Y32N@135623|Vibrionales 135623|Vibrionales E Acetyltransferase (GNAT) domain - - - ko:K03828 - - - - ko00000,ko01000 - - - Acetyltransf_1,Acetyltransf_7 k141_34463_11 1116375.VEJY3_13585 4.06e-82 244.0 COG3205@1|root,COG3205@2|Bacteria,1N85D@1224|Proteobacteria,1SCCN@1236|Gammaproteobacteria,1XXCR@135623|Vibrionales 135623|Vibrionales S Predicted membrane protein (DUF2061) VP2647 - - - - - - - - - - - DUF2061 k141_34463_12 1280001.BAOA01000048_gene1878 4.23e-208 602.0 COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,1RNEB@1236|Gammaproteobacteria,1XTVJ@135623|Vibrionales 135623|Vibrionales J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner valS GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 k141_21289_1 218284.CCDN010000008_gene4223 7.22e-100 310.0 COG0849@1|root,COG0849@2|Bacteria,1TP1Z@1239|Firmicutes,4HBAG@91061|Bacilli,1ZBRW@1386|Bacillus 91061|Bacilli D Cell division protein FtsA ftsA_1 - - - - - - - - - - - FtsA,PilM_2 k141_28331_1 218284.CCDN010000002_gene2746 1.05e-180 506.0 COG0501@1|root,COG0501@2|Bacteria,1TP23@1239|Firmicutes,4HB11@91061|Bacilli,1ZBW6@1386|Bacillus 91061|Bacilli O Belongs to the peptidase M48B family htpX - - ko:K03799 - M00743 - - ko00000,ko00002,ko01000,ko01002 - - - Peptidase_M48 k141_37907_1 521000.PROVRETT_05990 2.87e-15 76.3 2DBAD@1|root,2Z82M@2|Bacteria,1QWBK@1224|Proteobacteria,1T363@1236|Gammaproteobacteria,3Z9UV@586|Providencia 1236|Gammaproteobacteria S Bacteriophage replication protein O - - - - - - - - - - - - Phage_rep_O k141_36594_1 218284.CCDN010000005_gene3294 1.32e-25 102.0 COG0741@1|root,COG0741@2|Bacteria,1V6DD@1239|Firmicutes,4HIWA@91061|Bacilli,1ZH33@1386|Bacillus 91061|Bacilli M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) yjbJ - - - - - - - - - - - SLT k141_3668_5 1370122.JHXQ01000017_gene869 7.77e-159 497.0 COG0612@1|root,COG0612@2|Bacteria,1NAH6@1224|Proteobacteria,2U0S5@28211|Alphaproteobacteria,4BCFI@82115|Rhizobiaceae 28211|Alphaproteobacteria S Belongs to the peptidase M16 family pqqL - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C k141_3668_6 1190606.AJYG01000197_gene4235 2.45e-127 372.0 COG1133@1|root,COG1133@2|Bacteria,1QU39@1224|Proteobacteria,1T1PR@1236|Gammaproteobacteria,1XV6E@135623|Vibrionales 135623|Vibrionales I SbmA/BacA-like family - - - ko:K17938 - - - - ko00000,ko02000 9.A.18.1 - - SbmA_BacA k141_10763_1 42565.FP66_13785 1.47e-166 493.0 COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,1RP9N@1236|Gammaproteobacteria,1XHKJ@135619|Oceanospirillales 135619|Oceanospirillales OT Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell glnE - 2.7.7.42,2.7.7.89 ko:K00982 - - - - ko00000,ko01000 - - - GlnD_UR_UTase,GlnE k141_26286_1 1294265.JCM21738_1690 9.18e-99 291.0 28XAZ@1|root,2ZJ8Y@2|Bacteria,1V2XT@1239|Firmicutes,4HGD4@91061|Bacilli,1ZG66@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_135_1 42565.FP66_00415 6.52e-150 429.0 COG1804@1|root,COG1804@2|Bacteria,1MW1H@1224|Proteobacteria,1RN9B@1236|Gammaproteobacteria,1XID3@135619|Oceanospirillales 135619|Oceanospirillales C carnitine dehydratase - - - - - - - - - - - - CoA_transf_3 k141_8463_1 1121015.N789_12755 3.59e-58 200.0 COG3203@1|root,COG3203@2|Bacteria,1MXEB@1224|Proteobacteria,1RPY8@1236|Gammaproteobacteria,1X47V@135614|Xanthomonadales 135614|Xanthomonadales M Protein of unknown function (DUF1302) - - - - - - - - - - - - DUF1302 k141_15584_1 218284.CCDN010000001_gene607 1.29e-147 422.0 COG2334@1|root,COG2334@2|Bacteria,1V54J@1239|Firmicutes,4HH2K@91061|Bacilli,1ZB97@1386|Bacillus 91061|Bacilli S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response ysxE - - - - - - - - - - - APH k141_32173_1 42565.FP66_12515 1.26e-151 436.0 COG4303@1|root,COG4303@2|Bacteria,1MUR4@1224|Proteobacteria,1RPN8@1236|Gammaproteobacteria,1XIY4@135619|Oceanospirillales 135619|Oceanospirillales E With EutC catalyzes the formation of acetaldehyde and ammonia from ethanolamine - - 4.3.1.7 ko:K03735 ko00564,ko01100,map00564,map01100 - R00749 RC00370 ko00000,ko00001,ko01000 - - - EutB k141_17974_1 1279017.AQYJ01000020_gene1282 1.16e-113 360.0 COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,1RMYY@1236|Gammaproteobacteria,465WZ@72275|Alteromonadaceae 1236|Gammaproteobacteria M Mechanosensitive ion channel kefA - - - - - - - - - - - MS_channel k141_21537_1 1382305.AZUC01000046_gene596 8.18e-81 275.0 COG1404@1|root,COG1404@2|Bacteria,1TPH1@1239|Firmicutes,4HBQH@91061|Bacilli,26GW2@186818|Planococcaceae 91061|Bacilli O Peptidase inhibitor I9 prtS - 3.4.21.110,3.4.21.96 ko:K01361,ko:K08652 - - - - ko00000,ko01000,ko01002,ko03110 - - - FIVAR,Gram_pos_anchor,Inhibitor_I9,PA,Peptidase_S8,SLH,YSIRK_signal,fn3_5 k141_3680_2 1219076.N646_0338 0.0 937.0 COG2925@1|root,COG2925@2|Bacteria,1MV0U@1224|Proteobacteria,1RM85@1236|Gammaproteobacteria,1XT1P@135623|Vibrionales 135623|Vibrionales L COG2925 Exonuclease I sbcB - 3.1.11.1 ko:K01141 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_X-T_C,RNase_T k141_3680_3 754436.JCM19237_1976 6.54e-67 205.0 COG0346@1|root,COG0346@2|Bacteria,1RGZ8@1224|Proteobacteria,1S66M@1236|Gammaproteobacteria,1XXDJ@135623|Vibrionales 135623|Vibrionales E COG0346 Lactoylglutathione lyase and related lyases - - - ko:K08234 - - - - ko00000 - - - Glyoxalase k141_3680_4 1136163.M565_ctg1P0865 1.62e-100 295.0 COG1437@1|root,COG1437@2|Bacteria,1RBPX@1224|Proteobacteria,1S2EK@1236|Gammaproteobacteria,1XX0X@135623|Vibrionales 135623|Vibrionales F CYTH cyaB - 4.6.1.1 ko:K05873 ko00230,map00230 - R00089,R00434 RC00295 ko00000,ko00001,ko01000 - - - CYTH k141_3680_6 1116375.VEJY3_08420 1.7e-86 254.0 COG0346@1|root,COG0346@2|Bacteria,1RH8G@1224|Proteobacteria,1S629@1236|Gammaproteobacteria,1XXM8@135623|Vibrionales 135623|Vibrionales E COG0346 Lactoylglutathione lyase and related lyases - - - - - - - - - - - - Glyoxalase k141_3680_7 1238450.VIBNISOn1_560065 8.68e-38 127.0 COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,1SCKA@1236|Gammaproteobacteria,1XZ1Z@135623|Vibrionales 135623|Vibrionales S RNA recognition motif - - - - - - - - - - - - RRM_1 k141_3680_8 1116375.VEJY3_08405 7.85e-97 285.0 COG1309@1|root,COG1309@2|Bacteria,1R67Z@1224|Proteobacteria,1S63V@1236|Gammaproteobacteria,1Y2E4@135623|Vibrionales 135623|Vibrionales K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N k141_3680_9 1116375.VEJY3_08400 6.67e-91 267.0 COG3448@1|root,COG3448@2|Bacteria,1MXJG@1224|Proteobacteria,1RYFC@1236|Gammaproteobacteria,1XXB9@135623|Vibrionales 135623|Vibrionales T HPP family - - - - - - - - - - - - HPP k141_3680_10 1116375.VEJY3_08395 8.25e-110 318.0 COG0693@1|root,COG0693@2|Bacteria,1N8N6@1224|Proteobacteria,1S32P@1236|Gammaproteobacteria,1XUSN@135623|Vibrionales 135623|Vibrionales S DJ-1/PfpI family - - - - - - - - - - - - DJ-1_PfpI k141_3680_11 1116375.VEJY3_08390 1.94e-150 424.0 COG1794@1|root,COG1794@2|Bacteria,1MV03@1224|Proteobacteria,1RMHT@1236|Gammaproteobacteria,1XSX2@135623|Vibrionales 135623|Vibrionales M Aspartate racemase - - 5.1.1.13 ko:K01779 ko00250,ko01054,map00250,map01054 - R00491 RC00302 ko00000,ko00001,ko01000 - - - Asp_Glu_race k141_7219_2 1132442.KB889752_gene3746 1.42e-68 208.0 COG1366@1|root,COG1366@2|Bacteria,1V7FB@1239|Firmicutes,4HIQ6@91061|Bacilli,1ZGH2@1386|Bacillus 91061|Bacilli T antagonist rsbS - - ko:K17762 - - - - ko00000,ko03021 - - - STAS k141_8464_2 1131730.BAVI_02844 7.01e-36 138.0 COG0737@1|root,COG1404@1|root,COG5263@1|root,COG0737@2|Bacteria,COG1404@2|Bacteria,COG5263@2|Bacteria,1TPV2@1239|Firmicutes,4HB9S@91061|Bacilli,1ZAY0@1386|Bacillus 91061|Bacilli F Belongs to the 5'-nucleotidase family - - 3.1.3.5,3.1.3.6,3.1.4.16,3.6.1.45 ko:K01081,ko:K01119,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01562,R01569,R01664,R01877,R01968,R02088,R02102,R02148,R02323,R02370,R02719,R03346,R03537,R03538,R03929,R05135 RC00017,RC00078,RC00296 ko00000,ko00001,ko01000 - - - 5_nucleotid_C,CW_binding_1,Metallophos k141_28662_2 218284.CCDN010000001_gene1709 2.58e-108 327.0 COG2509@1|root,COG2509@2|Bacteria,1TP9I@1239|Firmicutes,4HB7F@91061|Bacilli,1ZCNU@1386|Bacillus 91061|Bacilli S FAD-dependent - - - ko:K07137 - - - - ko00000 - - - HI0933_like,NAD_binding_8 k141_36921_2 1453501.JELR01000005_gene1671 7.52e-97 288.0 COG0390@1|root,COG0390@2|Bacteria,1MV2N@1224|Proteobacteria,1RSGA@1236|Gammaproteobacteria,467K7@72275|Alteromonadaceae 1236|Gammaproteobacteria S Uncharacterised protein family (UPF0014) ybbM GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0009987,GO:0015075,GO:0016020,GO:0016021,GO:0019725,GO:0022857,GO:0030003,GO:0031224,GO:0031226,GO:0034220,GO:0042592,GO:0044425,GO:0044459,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071944,GO:0098771 - ko:K02069 - M00211 - - ko00000,ko00002,ko02000 9.B.25.1 - - UPF0014 k141_23850_1 218284.CCDN010000002_gene2640 2.28e-163 462.0 COG1277@1|root,COG1277@2|Bacteria,1TRV1@1239|Firmicutes,4HBBV@91061|Bacilli,1ZE79@1386|Bacillus 91061|Bacilli S ABC transporter (permease) bcrB - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_2 k141_27410_1 218284.CCDN010000001_gene1386 4.31e-110 322.0 COG2176@1|root,COG2176@2|Bacteria,1V332@1239|Firmicutes,4HFP2@91061|Bacilli,1ZHN2@1386|Bacillus 91061|Bacilli L 3' exoribonuclease, RNase T-like - - 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - RNase_T k141_3681_1 1294265.JCM21738_3300 7e-35 127.0 COG4864@1|root,COG4864@2|Bacteria,1TPTD@1239|Firmicutes,4HAIX@91061|Bacilli,1ZD1V@1386|Bacillus 91061|Bacilli S UPF0365 protein yqfA - - - - - - - - - - - YdfA_immunity k141_3681_2 1294265.JCM21738_3299 1.97e-29 105.0 COG1030@1|root,COG1030@2|Bacteria 2|Bacteria - - yqeZ - - ko:K07403 - - - - ko00000 - - - CLP_protease,NfeD,SDH_sah k141_13215_1 1042377.AFPJ01000014_gene1644 0.0 1172.0 COG3525@1|root,COG3525@2|Bacteria,1MVDE@1224|Proteobacteria,1RMNI@1236|Gammaproteobacteria,465K7@72275|Alteromonadaceae 1236|Gammaproteobacteria G Putative carbohydrate binding domain chb - 3.2.1.52 ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 M00079 R00022,R06004,R11316 RC00049 ko00000,ko00001,ko00002,ko01000,ko03110 - GH20 - CHB_HEX,CHB_HEX_C,Glyco_hydro_20,Glyco_hydro_20b k141_13215_2 236097.ADG881_2305 1.66e-60 196.0 COG2227@1|root,COG2227@2|Bacteria,1REWV@1224|Proteobacteria,1T1J3@1236|Gammaproteobacteria,1XPGB@135619|Oceanospirillales 135619|Oceanospirillales H COG0500 SAM-dependent methyltransferases - - - - - - - - - - - - Methyltransf_23 k141_13215_3 1279017.AQYJ01000023_gene3197 2.32e-294 815.0 COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,1RMD2@1236|Gammaproteobacteria,46508@72275|Alteromonadaceae 1236|Gammaproteobacteria E Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate alkJ - 1.1.99.1 ko:K00108 ko00260,ko01100,map00260,map01100 M00555 R01025 RC00087 ko00000,ko00001,ko00002,ko01000 - - - GMC_oxred_C,GMC_oxred_N k141_13215_4 1042377.AFPJ01000014_gene1642 8.34e-116 340.0 COG0500@1|root,COG2226@2|Bacteria,1MXDY@1224|Proteobacteria,1RMU7@1236|Gammaproteobacteria,466NC@72275|Alteromonadaceae 1236|Gammaproteobacteria Q COG0500 SAM-dependent methyltransferases rrmA GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008270,GO:0008649,GO:0008757,GO:0008989,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.187 ko:K00563 - - R07233 RC00003 ko00000,ko01000,ko03009 - - - Methyltransf_11,Methyltransf_25,Methyltransf_31 k141_13215_5 1279017.AQYJ01000023_gene3199 1.33e-86 256.0 COG0590@1|root,COG0590@2|Bacteria,1RGU0@1224|Proteobacteria,1S60Z@1236|Gammaproteobacteria,467E7@72275|Alteromonadaceae 1236|Gammaproteobacteria FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) tadA GO:0002097,GO:0002100,GO:0003674,GO:0003824,GO:0004000,GO:0005488,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008251,GO:0008270,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0052717,GO:0071704,GO:0090304,GO:1901360 3.5.4.33 ko:K11991 - - R10223 RC00477 ko00000,ko01000,ko03016 - - - MafB19-deam,dCMP_cyt_deam_1 k141_13215_6 1279017.AQYJ01000023_gene3200 5.84e-70 214.0 COG1226@1|root,31669@2|Bacteria,1RIW0@1224|Proteobacteria,1S6HC@1236|Gammaproteobacteria,4688E@72275|Alteromonadaceae 1236|Gammaproteobacteria P Ion transport 2 domain protein - - - - - - - - - - - - Ion_trans_2 k141_13215_7 1279017.AQYJ01000023_gene3202 1.45e-176 504.0 COG0477@1|root,COG2814@2|Bacteria,1MW19@1224|Proteobacteria,1RMSZ@1236|Gammaproteobacteria,4661G@72275|Alteromonadaceae 1236|Gammaproteobacteria EGP Major Facilitator Superfamily bcr - - ko:K07552 - - - - ko00000,ko02000 2.A.1.2 - - MFS_1 k141_11970_1 1279017.AQYJ01000023_gene3241 6.69e-250 692.0 COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,1RMDI@1236|Gammaproteobacteria,4650C@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG0348 Polyferredoxin ccoG - - - - - - - - - - - Fer4_18,Fer4_5,FixG_C k141_11970_2 1453501.JELR01000006_gene25 3.04e-187 523.0 COG2010@1|root,COG2010@2|Bacteria,1MUCW@1224|Proteobacteria,1RPYJ@1236|Gammaproteobacteria,464W3@72275|Alteromonadaceae 1236|Gammaproteobacteria C C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex ccoP - - ko:K00406 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002 3.D.4.3 - iJN746.PP_4253 Cytochrome_CBB3,FixP_N k141_11970_3 1453501.JELR01000006_gene26 3.56e-23 91.3 COG4736@1|root,COG4736@2|Bacteria 2|Bacteria O Cbb3-type cytochrome oxidase ccoQ - - ko:K00407 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002 3.D.4.3 - - FixQ k141_11970_4 1453501.JELR01000006_gene27 2.38e-129 369.0 COG2993@1|root,COG2993@2|Bacteria,1MXEY@1224|Proteobacteria,1RPU6@1236|Gammaproteobacteria,464XG@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG2993 Cbb3-type cytochrome oxidase, cytochrome c subunit ccoO - - ko:K00405 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002 3.D.4.3 - - FixO k141_11970_5 1279017.AQYJ01000023_gene3237 0.0 914.0 COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,1RM7I@1236|Gammaproteobacteria,4654T@72275|Alteromonadaceae 1236|Gammaproteobacteria C Belongs to the heme-copper respiratory oxidase family ccoN GO:0003674,GO:0003824,GO:0004129,GO:0005215,GO:0005488,GO:0005506,GO:0005507,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008144,GO:0008150,GO:0008152,GO:0008324,GO:0009055,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015002,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0015975,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016310,GO:0016491,GO:0016675,GO:0016676,GO:0016705,GO:0017144,GO:0019411,GO:0019637,GO:0019646,GO:0019693,GO:0019825,GO:0020037,GO:0022857,GO:0022890,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0034641,GO:0036094,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045154,GO:0045333,GO:0046034,GO:0046483,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0055114,GO:0070069,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0097159,GO:0098655,GO:0098660,GO:0098662,GO:1901135,GO:1901360,GO:1901363,GO:1901564,GO:1902600 1.9.3.1 ko:K00404 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - COX1 k141_11970_6 1453501.JELR01000006_gene29 1.31e-286 783.0 COG0137@1|root,COG0137@2|Bacteria,1MV0Y@1224|Proteobacteria,1RMEC@1236|Gammaproteobacteria,464YE@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the argininosuccinate synthase family. Type 1 subfamily argG GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 M00029,M00844,M00845 R01954 RC00380,RC00629 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Arginosuc_synth k141_11970_7 1453501.JELR01000006_gene30 4.56e-212 590.0 COG0418@1|root,COG0418@2|Bacteria,1MUYP@1224|Proteobacteria,1RNEN@1236|Gammaproteobacteria,4642S@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate pyrC GO:0003674,GO:0003824,GO:0004151,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - iSBO_1134.SBO_2002,iYL1228.KPN_01074 Amidohydro_1 k141_11970_8 1279017.AQYJ01000023_gene3234 2.75e-139 396.0 COG0847@1|root,COG0847@2|Bacteria,1MUPK@1224|Proteobacteria,1RMMH@1236|Gammaproteobacteria,465BF@72275|Alteromonadaceae 1236|Gammaproteobacteria L Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis rnt GO:0000287,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004540,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0031123,GO:0034470,GO:0034641,GO:0034660,GO:0042780,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 - ko:K03683 - - - - ko00000,ko01000,ko03016 - - - RNase_T k141_11970_9 1453501.JELR01000006_gene32 2.77e-314 874.0 COG3509@1|root,COG3509@2|Bacteria,1R66H@1224|Proteobacteria,1SZAS@1236|Gammaproteobacteria,466AM@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Esterase PHB depolymerase - - - - - - - - - - - - Esterase_phd k141_14387_1 1280001.BAOA01000051_gene1509 2.78e-95 283.0 COG1218@1|root,COG1218@2|Bacteria,1N0GY@1224|Proteobacteria,1RP5A@1236|Gammaproteobacteria,1XUIT@135623|Vibrionales 135623|Vibrionales P COG1218 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase cysQ - 3.1.3.7 ko:K01082 ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130 - R00188,R00508 RC00078 ko00000,ko00001,ko01000,ko03016 - - - Inositol_P k141_14387_2 1219076.N646_2332 2.47e-141 403.0 2CBG9@1|root,32RTB@2|Bacteria,1R86M@1224|Proteobacteria,1RNNN@1236|Gammaproteobacteria,1XV6Z@135623|Vibrionales 135623|Vibrionales S Type II secretion system (T2SS), protein N epsN GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - ko:K02463 ko05111,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSN k141_14387_3 1116375.VEJY3_00655 1.79e-106 308.0 COG3149@1|root,COG3149@2|Bacteria,1N8VZ@1224|Proteobacteria,1S8X3@1236|Gammaproteobacteria,1XU6P@135623|Vibrionales 135623|Vibrionales U Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins epsM GO:0008150,GO:0009405,GO:0044419,GO:0051704 - ko:K02462 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSM k141_14387_4 1116375.VEJY3_00650 4.2e-252 696.0 COG3297@1|root,COG3297@2|Bacteria,1NVVW@1224|Proteobacteria,1S01F@1236|Gammaproteobacteria,1XUFK@135623|Vibrionales 135623|Vibrionales U Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins gspL GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - ko:K02461 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - GspL_C,T2SSL k141_14387_5 1116375.VEJY3_00645 5.99e-40 140.0 COG3156@1|root,COG3156@2|Bacteria,1RC9P@1224|Proteobacteria,1T072@1236|Gammaproteobacteria,1XT6W@135623|Vibrionales 135623|Vibrionales U COG3156 Type II secretory pathway, component PulK epsK - - ko:K02460 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSK k141_34583_2 1453501.JELR01000001_gene2905 4.88e-207 586.0 COG2067@1|root,COG2067@2|Bacteria,1MUU4@1224|Proteobacteria,1RQZJ@1236|Gammaproteobacteria,465E0@72275|Alteromonadaceae 1236|Gammaproteobacteria I Long-chain fatty acid fadL GO:0003674,GO:0005215,GO:0005319,GO:0005324,GO:0005342,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006820,GO:0006869,GO:0008028,GO:0008150,GO:0008509,GO:0008514,GO:0009279,GO:0010876,GO:0015075,GO:0015245,GO:0015267,GO:0015288,GO:0015318,GO:0015483,GO:0015711,GO:0015718,GO:0015849,GO:0015908,GO:0015909,GO:0016020,GO:0019867,GO:0022803,GO:0022829,GO:0022834,GO:0022836,GO:0022857,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0034220,GO:0044462,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098656,GO:1903825,GO:1905039 - ko:K06076 - - - - ko00000,ko02000 1.B.9 - iECs_1301.ECs3227,iG2583_1286.G2583_2880,iZ_1308.Z3608 Toluene_X k141_34583_3 1453501.JELR01000001_gene2904 1.83e-82 254.0 COG3147@1|root,COG3147@2|Bacteria,1N9GW@1224|Proteobacteria,1T2WQ@1236|Gammaproteobacteria,46DE4@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF3108) - - - - - - - - - - - - DUF3108 k141_34583_4 1042377.AFPJ01000020_gene2096 1.26e-105 310.0 COG0299@1|root,COG0299@2|Bacteria,1MWN1@1224|Proteobacteria,1RMHS@1236|Gammaproteobacteria,466JV@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate purN GO:0003674,GO:0003824,GO:0004644,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716 2.1.2.2 ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04325,R04326 RC00026,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b2500,iBWG_1329.BWG_2264,iECDH10B_1368.ECDH10B_2666,iECDH1ME8569_1439.ECDH1ME8569_2426,iEcDH1_1363.EcDH1_1169,iJO1366.b2500,iJR904.b2500,iY75_1357.Y75_RS13050 Formyl_trans_N k141_34583_5 1279017.AQYJ01000021_gene2800 4.32e-223 618.0 COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,1RNZZ@1236|Gammaproteobacteria,4644R@72275|Alteromonadaceae 1236|Gammaproteobacteria F Phosphoribosylformylglycinamidine cyclo-ligase purM GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.1 ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04208 RC01100 ko00000,ko00001,ko00002,ko01000 - - iECSF_1327.ECSF_2340 AIRS,AIRS_C k141_34583_6 1279017.AQYJ01000021_gene2801 8.61e-60 196.0 COG3249@1|root,COG3249@2|Bacteria,1N0PD@1224|Proteobacteria,1S9C4@1236|Gammaproteobacteria,466SQ@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria VV2512 - - ko:K09938 - - - - ko00000 - - - DUF2066 k141_13216_1 446465.Bfae_30480 5.32e-06 52.8 COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4FCBX@85020|Dermabacteraceae 201174|Actinobacteria EGP major facilitator superfamily - - - - - - - - - - - - MFS_1 k141_21538_1 42565.FP66_08675 4.59e-130 380.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1XH6F@135619|Oceanospirillales 135619|Oceanospirillales T Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - ko:K10126 ko02020,map02020 M00504 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat k141_21538_2 42565.FP66_08670 2.23e-95 295.0 COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RQIN@1236|Gammaproteobacteria,1XHAU@135619|Oceanospirillales 135619|Oceanospirillales T Signal transduction histidine kinase - - 2.7.13.3 ko:K10125 ko02020,map02020 M00504 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS,PAS_9,dCache_1 k141_3682_1 1279017.AQYJ01000023_gene3242 3.22e-71 219.0 COG3198@1|root,COG3198@2|Bacteria,1N75J@1224|Proteobacteria,1SC87@1236|Gammaproteobacteria,468BX@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria ccoH - - ko:K09926 - - - - ko00000 - - - FixH k141_3682_2 1042377.AFPJ01000045_gene2571 5.7e-23 97.4 COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,464SF@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG2217 Cation transport ATPase ccoI - 3.6.3.4 ko:K01533 - - R00086 RC00002 ko00000,ko01000 3.A.3.5 - - ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase k141_26287_1 1453501.JELR01000001_gene2048 9.4e-18 79.7 COG2227@1|root,COG2227@2|Bacteria,1MU89@1224|Proteobacteria,1RMV7@1236|Gammaproteobacteria,464RA@72275|Alteromonadaceae 1236|Gammaproteobacteria H O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway ubiG GO:0003674,GO:0003824,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008289,GO:0008689,GO:0008757,GO:0009058,GO:0009108,GO:0009628,GO:0009651,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0042180,GO:0042181,GO:0042538,GO:0043167,GO:0043168,GO:0043431,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0051188,GO:0061542,GO:0071704,GO:1901576,GO:1901611,GO:1901661,GO:1901663 2.1.1.222,2.1.1.64 ko:K00568 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04988,R05614,R08769,R08781 RC00003,RC00392,RC01895 ko00000,ko00001,ko00002,ko01000 - - iE2348C_1286.E2348C_2376 Methyltransf_23 k141_31025_1 748449.Halha_2398 5.29e-05 48.9 COG1216@1|root,COG1216@2|Bacteria,1UIHC@1239|Firmicutes,25F9A@186801|Clostridia,3WADS@53433|Halanaerobiales 186801|Clostridia S PFAM Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 k141_31025_2 2002.JOEQ01000044_gene835 9.9e-35 139.0 COG0438@1|root,COG0438@2|Bacteria,2GJBP@201174|Actinobacteria,4EHWW@85012|Streptosporangiales 201174|Actinobacteria M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1,Stealth_CR1,Stealth_CR2,Stealth_CR3,Stealth_CR4 k141_31025_3 857087.Metme_1342 7.14e-122 365.0 COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,1RYBJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria M PFAM Glycosyl transferase, group 1 - - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1 k141_31025_4 493475.GARC_1570 3.89e-131 390.0 COG0438@1|root,COG0438@2|Bacteria,1R2WM@1224|Proteobacteria,1RY41@1236|Gammaproteobacteria,469G9@72275|Alteromonadaceae 1236|Gammaproteobacteria M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1 k141_31025_5 1266914.ATUK01000011_gene2440 9.34e-261 737.0 COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,1RQ7D@1236|Gammaproteobacteria,1WWE5@135613|Chromatiales 135613|Chromatiales E Asparagine synthase, glutamine-hydrolyzing - - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 k141_31025_6 420662.Mpe_A0727 6.48e-64 216.0 COG1835@1|root,COG1835@2|Bacteria,1NIG3@1224|Proteobacteria 1224|Proteobacteria I Acyltransferase family - - - - - - - - - - - - Acyl_transf_3 k141_31025_7 754436.JCM19237_3644 2.29e-139 416.0 COG1269@1|root,COG1269@2|Bacteria,1MXZG@1224|Proteobacteria,1RQYZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria C eight transmembrane protein EpsH - - - - - - - - - - - - DUF3485,Exosortase_EpsH k141_31025_8 314278.NB231_08435 1.62e-45 163.0 COG0438@1|root,COG0438@2|Bacteria,1MVIM@1224|Proteobacteria,1RPB8@1236|Gammaproteobacteria,1WWKU@135613|Chromatiales 135613|Chromatiales M Sugar transferase, PEP-CTERM EpsH1 system associated - - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_4 k141_2495_2 218284.CCDN010000003_gene2974 7.69e-114 338.0 COG3583@1|root,COG3584@1|root,COG3583@2|Bacteria,COG3584@2|Bacteria,1TTIK@1239|Firmicutes,4HC79@91061|Bacilli,1ZC0Q@1386|Bacillus 91061|Bacilli T protein conserved in bacteria yabE - - - - - - - - - - - 3D,DUF348,G5 k141_8465_1 42565.FP66_07890 1.97e-116 345.0 COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,1RPM2@1236|Gammaproteobacteria,1XHE1@135619|Oceanospirillales 135619|Oceanospirillales L it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins - - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C,Intein_splicing,LAGLIDADG_3 k141_136_1 218284.CCDN010000001_gene1027 2.69e-166 472.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,1ZB7V@1386|Bacillus 91061|Bacilli I Belongs to the thiolase family atoB GO:0003674,GO:0003824,GO:0003988,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - iYO844.BSU24170 Thiolase_C,Thiolase_N k141_17976_1 644966.Tmar_1074 1.23e-53 190.0 COG0249@1|root,COG0249@2|Bacteria,1TPRJ@1239|Firmicutes,248GI@186801|Clostridia,3WCCC@538999|Clostridiales incertae sedis 186801|Clostridia L that it carries out the mismatch recognition step. This protein has a weak ATPase activity mutS - - ko:K03555 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V k141_4871_1 1123500.ATUU01000002_gene745 6.45e-40 144.0 COG0313@1|root,COG0313@2|Bacteria,1TP6U@1239|Firmicutes,4HAH8@91061|Bacilli,4AWUP@81850|Leuconostocaceae 91061|Bacilli H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA rsmI GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 2.1.1.198 ko:K07056 - - - - ko00000,ko01000,ko03009 - - - TP_methylase k141_13217_1 218284.CCDN010000001_gene275 1.32e-103 308.0 COG1473@1|root,COG1473@2|Bacteria,1TQ7R@1239|Firmicutes,4HB6M@91061|Bacilli,1ZB9M@1386|Bacillus 91061|Bacilli S amidohydrolase amhX - - ko:K14665 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 k141_33382_1 796606.BMMGA3_00030 1.38e-218 625.0 COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,4HAHY@91061|Bacilli,1ZB8F@1386|Bacillus 91061|Bacilli L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrA - 5.99.1.3 ko:K02469 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseA_C,DNA_topoisoIV k141_14389_1 406124.ACPC01000047_gene1813 7.48e-05 43.9 COG1309@1|root,COG1309@2|Bacteria,1V89E@1239|Firmicutes,4HH86@91061|Bacilli,1ZFSK@1386|Bacillus 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - TetR_C_8,TetR_N k141_14389_2 406124.ACPC01000047_gene1812 4.05e-58 197.0 COG1033@1|root,COG1033@2|Bacteria,1VSWA@1239|Firmicutes,4HBIV@91061|Bacilli 91061|Bacilli S MMPL family ydfJ - - ko:K07003 - - - - ko00000 - - - MMPL k141_3683_1 1294265.JCM21738_1829 8.91e-09 62.0 COG3468@1|root,COG3468@2|Bacteria 2|Bacteria MU cell adhesion - - - ko:K18491 ko04550,map04550 - - - ko00000,ko00001,ko03000 - - - Collagen,DUF4132,Gln_amidase k141_22702_2 1279017.AQYJ01000028_gene2104 2e-241 665.0 COG0191@1|root,COG0191@2|Bacteria,1MURX@1224|Proteobacteria,1RQUC@1236|Gammaproteobacteria,46402@72275|Alteromonadaceae 1236|Gammaproteobacteria G COG0191 Fructose tagatose bisphosphate aldolase fba - 4.1.2.13 ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_4960 F_bP_aldolase k141_20279_1 1219076.N646_1915 4.09e-77 238.0 COG1162@1|root,COG1162@2|Bacteria,1MUEF@1224|Proteobacteria,1RMMB@1236|Gammaproteobacteria,1XTBR@135623|Vibrionales 135623|Vibrionales S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit rsgA - 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 - R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 - - - RsgA_GTPase k141_34606_4 1219076.N646_3499 4.79e-32 112.0 2BHA8@1|root,32BBT@2|Bacteria,1QIVM@1224|Proteobacteria,1TGRN@1236|Gammaproteobacteria,1XYAN@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_34606_5 1116375.VEJY3_15906 1.79e-89 263.0 COG2259@1|root,COG2259@2|Bacteria,1RDYW@1224|Proteobacteria,1S3RT@1236|Gammaproteobacteria,1XX1H@135623|Vibrionales 135623|Vibrionales S TQO small subunit DoxD - - - ko:K15977 - - - - ko00000 - - - DoxX k141_34606_6 223926.28808180 1.5e-138 394.0 COG1741@1|root,COG1741@2|Bacteria,1MVSW@1224|Proteobacteria,1RNVS@1236|Gammaproteobacteria,1Y299@135623|Vibrionales 135623|Vibrionales S Belongs to the pirin family - - - ko:K06911 - - - - ko00000 - - - Pirin k141_34606_7 1116375.VEJY3_15896 3.57e-204 566.0 COG0583@1|root,COG0583@2|Bacteria,1MXXA@1224|Proteobacteria,1RREE@1236|Gammaproteobacteria,1XUTM@135623|Vibrionales 135623|Vibrionales K Transcriptional regulator hdfR - - - - - - - - - - - HTH_1,LysR_substrate k141_34606_8 1116375.VEJY3_15891 7.48e-79 234.0 COG3085@1|root,COG3085@2|Bacteria,1N4FH@1224|Proteobacteria,1SC65@1236|Gammaproteobacteria,1XXA3@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria - - - ko:K09897 - - - - ko00000 - - - DUF413 k141_34606_9 223926.28808177 5.43e-54 169.0 2E4VZ@1|root,32ZQ5@2|Bacteria,1N7XP@1224|Proteobacteria,1SCVI@1236|Gammaproteobacteria,1XYDV@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF3081) - - - - - - - - - - - - DUF3081 k141_34606_10 223926.28808176 1.3e-123 355.0 COG0363@1|root,COG0363@2|Bacteria,1MVEA@1224|Proteobacteria,1RQ2V@1236|Gammaproteobacteria,1XV23@135623|Vibrionales 135623|Vibrionales G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion nagB - 3.5.99.6 ko:K02564 ko00520,ko01100,map00520,map01100 - R00765 RC00163 ko00000,ko00001,ko01000 - - - Glucosamine_iso k141_6357_1 218284.CCDN010000001_gene1450 8.05e-63 206.0 COG0665@1|root,COG0665@2|Bacteria,1VTRW@1239|Firmicutes,4HD2K@91061|Bacilli,1ZCZM@1386|Bacillus 91061|Bacilli E Glycine oxidase thiO GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016043,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0022607,GO:0034641,GO:0036094,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043436,GO:0043799,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0072527,GO:0072528,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.4.3.19 ko:K03153 ko00730,ko01100,map00730,map01100 - R07463 RC01788 ko00000,ko00001,ko01000 - - - DAO k141_7429_1 1294265.JCM21738_4351 2.97e-138 394.0 COG0030@1|root,COG0030@2|Bacteria,1TP9W@1239|Firmicutes,4HA4R@91061|Bacilli,1ZBZX@1386|Bacillus 91061|Bacilli J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits ksgA GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 ko:K02528 - - R10716 RC00003,RC03257 ko00000,ko01000,ko03009 - - - RrnaAD k141_5029_1 522306.CAP2UW1_3419 6.29e-19 85.5 COG4263@1|root,COG4263@2|Bacteria,1MVIH@1224|Proteobacteria,2VM8J@28216|Betaproteobacteria 28216|Betaproteobacteria C Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide nosZ - 1.7.2.4 ko:K00376 ko00910,ko01120,map00910,map01120 M00529 R02804 RC02861 ko00000,ko00001,ko00002,ko01000 - - - Cupredoxin_1 k141_5029_2 929713.NIASO_09240 1.37e-24 104.0 COG4314@1|root,COG4314@2|Bacteria,4NIPU@976|Bacteroidetes,1IR80@117747|Sphingobacteriia 976|Bacteroidetes C lipoprotein involved in nitrous oxide reduction - - - ko:K19342 - - - - ko00000 - - - NosL k141_37077_2 1042377.AFPJ01000010_gene1484 3.43e-44 144.0 COG2331@1|root,COG2331@2|Bacteria,1N6Q9@1224|Proteobacteria,1SCJS@1236|Gammaproteobacteria,468ET@72275|Alteromonadaceae 1236|Gammaproteobacteria S Putative regulatory protein - - - - - - - - - - - - Zn-ribbon_8 k141_19297_1 1294265.JCM21738_4173 3.5e-67 223.0 COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,4H9RZ@91061|Bacilli,1ZBEA@1386|Bacillus 91061|Bacilli NT chemotaxis protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - 4HB_MCP_1,HAMP,MCPsignal k141_16975_1 345219.Bcoa_0208 8.92e-11 62.0 COG1875@1|root,COG1875@2|Bacteria,1UHTD@1239|Firmicutes,4HA4V@91061|Bacilli,1ZDIF@1386|Bacillus 91061|Bacilli T ATPase related to phosphate starvation-inducible protein PhoH ylaK - - ko:K07175 - - - - ko00000 - - - PIN_4,PhoH k141_25270_1 218284.CCDN010000004_gene3091 3.24e-94 291.0 COG1109@1|root,COG1109@2|Bacteria,1TP2N@1239|Firmicutes,4HADU@91061|Bacilli,1ZBEM@1386|Bacillus 91061|Bacilli G Phosphoglucomutase pgcA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 5.4.2.2 ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00549 R00959,R01057,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV k141_26609_2 218284.CCDN010000001_gene577 4.51e-116 348.0 COG1053@1|root,COG1053@2|Bacteria,1TPAR@1239|Firmicutes,4HBVG@91061|Bacilli,1ZBRD@1386|Bacillus 91061|Bacilli C succinate dehydrogenase sdhA GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0022900,GO:0044237,GO:0045333,GO:0055114 1.3.5.1,1.3.5.4 ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS05640 FAD_binding_2,Succ_DH_flav_C k141_33556_1 1448860.BBJO01000009_gene842 1.96e-70 236.0 COG0272@1|root,arCOG04754@2157|Archaea,2XTQT@28890|Euryarchaeota,23S29@183963|Halobacteria 183963|Halobacteria L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA ligA - 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - - BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5 k141_35906_1 584708.Apau_1699 6.47e-40 145.0 COG0568@1|root,COG0568@2|Bacteria,3TACS@508458|Synergistetes 508458|Synergistetes K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth sigA - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 k141_8626_1 1453501.JELR01000005_gene1590 1.78e-127 403.0 COG1520@1|root,COG2133@1|root,COG1520@2|Bacteria,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,1RNGN@1236|Gammaproteobacteria,465UX@72275|Alteromonadaceae 1236|Gammaproteobacteria G Glucose / Sorbosone dehydrogenase - - - - - - - - - - - - Big_2,CBM26,Cytochrome_CBB3,GSDH,PSCyt3,PSD2,PSD3,PSD4,PSD5 k141_31235_1 400668.Mmwyl1_0166 1.91e-16 79.7 2DM33@1|root,31HZ0@2|Bacteria,1RJQ4@1224|Proteobacteria,1S7SM@1236|Gammaproteobacteria,1XMCE@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_28880_1 218284.CCDN010000002_gene2231 2.88e-95 286.0 COG4106@1|root,COG4106@2|Bacteria,1TRDY@1239|Firmicutes,4HEFZ@91061|Bacilli,1ZCF7@1386|Bacillus 91061|Bacilli S O-methyltransferase - - - - - - - - - - - - Methyltransf_12,Methyltransf_25,Methyltransf_31 k141_3915_1 218284.CCDN010000001_gene586 3.94e-107 313.0 COG0689@1|root,COG0689@2|Bacteria,1TQM3@1239|Firmicutes,4HBH3@91061|Bacilli,1ZBXN@1386|Bacillus 91061|Bacilli J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates rph GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006401,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043170,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 ko:K00989 - - - - ko00000,ko01000,ko03016 - - - Ham1p_like,RNase_PH,RNase_PH_C k141_13417_2 1169144.KB910984_gene3842 7.04e-57 186.0 COG4977@1|root,COG4977@2|Bacteria,1V34W@1239|Firmicutes,4HGHX@91061|Bacilli,1ZEN3@1386|Bacillus 91061|Bacilli K helix_turn_helix, arabinose operon control protein - - - - - - - - - - - - HTH_18 k141_21710_1 1273538.G159_03860 1.26e-48 162.0 COG1708@1|root,COG1708@2|Bacteria,1UD4J@1239|Firmicutes,4HDMK@91061|Bacilli,26DGY@186818|Planococcaceae 91061|Bacilli S nucleotidyltransferase activity - - - - - - - - - - - - NTP_transf_2 k141_32303_1 713586.KB900536_gene531 7.93e-21 95.1 COG3202@1|root,COG3202@2|Bacteria,1QXXQ@1224|Proteobacteria,1S2KU@1236|Gammaproteobacteria 1236|Gammaproteobacteria C TLC ATP/ADP transporter - - - - - - - - - - - - TLC k141_24042_1 485918.Cpin_2207 6.5e-18 85.5 COG3829@1|root,COG4565@1|root,COG3829@2|Bacteria,COG4565@2|Bacteria,4PM5Y@976|Bacteroidetes 976|Bacteroidetes KT PFAM sigma-54 factor interaction domain-containing protein - - - - - - - - - - - - HTH_8,PAS_9,Response_reg,Sigma54_activat,cNMP_binding k141_2696_1 1279017.AQYJ01000028_gene2375 3.73e-182 520.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPWS@1236|Gammaproteobacteria,464W9@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0488 ATPase components of ABC transporters with duplicated ATPase domains yjjK GO:0003674,GO:0003824,GO:0005488,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:2000112,GO:2000113 3.6.3.25 ko:K06020 - - - - ko00000,ko01000 - - - ABC_tran,ABC_tran_Xtn k141_37078_1 1294265.JCM21738_2451 2.58e-107 311.0 COG4581@1|root,COG4581@2|Bacteria,1TRYX@1239|Firmicutes,4HU79@91061|Bacilli,1ZE6K@1386|Bacillus 91061|Bacilli L COG0513 Superfamily II DNA and RNA helicases - - 3.6.4.13 ko:K17675 - - - - ko00000,ko01000,ko03029 - - - Helicase_C k141_1430_2 1279017.AQYJ01000022_gene2596 2.97e-52 168.0 2E5XZ@1|root,330MS@2|Bacteria,1NBN8@1224|Proteobacteria,1SCZT@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_1430_3 1453501.JELR01000001_gene3256 1.07e-86 257.0 COG1803@1|root,COG1803@2|Bacteria,1RD3D@1224|Proteobacteria,1S3XN@1236|Gammaproteobacteria,46733@72275|Alteromonadaceae 1236|Gammaproteobacteria G methylglyoxal synthase mgsA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0008150,GO:0008152,GO:0008929,GO:0009058,GO:0009438,GO:0009987,GO:0016829,GO:0016835,GO:0016838,GO:0019242,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0071704,GO:1901576 4.2.3.3 ko:K01734 ko00640,ko01120,map00640,map01120 - R01016 RC00424 ko00000,ko00001,ko01000 - - iECUMN_1333.ECUMN_1153,iYL1228.KPN_00992 MGS k141_1430_5 1042377.AFPJ01000035_gene2643 6.17e-166 466.0 COG3483@1|root,COG3483@2|Bacteria,1MW68@1224|Proteobacteria,1RXYM@1236|Gammaproteobacteria,4669G@72275|Alteromonadaceae 1236|Gammaproteobacteria E Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety kynA GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006084,GO:0006139,GO:0006163,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009117,GO:0009150,GO:0009259,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019442,GO:0019637,GO:0019693,GO:0019752,GO:0020037,GO:0022607,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043603,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051186,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0072521,GO:0097159,GO:1901135,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.11 ko:K00453 ko00380,ko01100,map00380,map01100 M00038 R00678 RC00356 ko00000,ko00001,ko00002,ko01000 - - - Trp_dioxygenase k141_18208_1 1279017.AQYJ01000029_gene3788 1.08e-57 184.0 COG5488@1|root,COG5488@2|Bacteria 2|Bacteria S Integral membrane protein (DUF2244) - - - - - - - - - - - - DUF2244 k141_34771_1 1453501.JELR01000005_gene1785 4.2e-151 440.0 COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,1RNKA@1236|Gammaproteobacteria,464PF@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source nadE - 6.3.1.5,6.3.5.1 ko:K01916,ko:K01950 ko00760,ko01100,map00760,map01100 M00115 R00189,R00257 RC00010,RC00100 ko00000,ko00001,ko00002,ko01000 - - - CN_hydrolase,NAD_synthase k141_12292_2 218284.CCDN010000005_gene3309 2.04e-97 284.0 2ANER@1|root,31DDD@2|Bacteria,1V46U@1239|Firmicutes,4HH0C@91061|Bacilli,1ZFW2@1386|Bacillus 91061|Bacilli S stage V sporulation protein AC spoVAC - - ko:K06405 - - - - ko00000 - - - SpoVAC_SpoVAEB k141_12292_3 218284.CCDN010000005_gene3308 1.82e-16 74.3 2CY4V@1|root,32T3F@2|Bacteria,1VDQ0@1239|Firmicutes,4HKEQ@91061|Bacilli,1ZIB4@1386|Bacillus 91061|Bacilli S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) - - - - - - - - - - - - Spore_YhcN_YlaJ k141_15779_1 1453501.JELR01000001_gene2579 3.42e-89 275.0 29FM1@1|root,302IP@2|Bacteria,1RHJK@1224|Proteobacteria,1S8M8@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - Ter k141_29954_1 1340434.AXVA01000003_gene2389 1.47e-62 200.0 COG4191@1|root,COG4191@2|Bacteria,1TSPI@1239|Firmicutes,4HCVV@91061|Bacilli,1ZE31@1386|Bacillus 91061|Bacilli T GHKL domain - - 2.7.13.3 ko:K07697 ko02020,map02020 M00485 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - 5TM-5TMR_LYT,HATPase_c,HisKA k141_10987_3 1449044.JMLE01000021_gene2001 4.93e-10 64.7 COG2314@1|root,COG3064@1|root,COG2314@2|Bacteria,COG3064@2|Bacteria,2I3NK@201174|Actinobacteria,1WCPA@1268|Micrococcaceae 201174|Actinobacteria M Host cell surface-exposed lipoprotein - - - - - - - - - - - - Lipoprotein_Ltp,PASTA k141_33589_1 436229.JOEH01000005_gene2967 0.000355 48.5 COG2755@1|root,COG3209@1|root,COG4372@1|root,COG2755@2|Bacteria,COG3209@2|Bacteria,COG4372@2|Bacteria,2GMBB@201174|Actinobacteria,2NGBE@228398|Streptacidiphilus 201174|Actinobacteria M Laminin G domain - - - - - - - - - - - - Laminin_G_3,PT-HINT,RHS_repeat,SCP1201-deam k141_25289_1 218284.CCDN010000005_gene3180 5.35e-168 470.0 COG1131@1|root,COG1131@2|Bacteria,1TQIH@1239|Firmicutes,4HA2B@91061|Bacilli,1ZBAI@1386|Bacillus 91061|Bacilli V transporter (ATP-binding protein) ecsA - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_9800_1 42565.FP66_01330 9.35e-98 294.0 COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,1RPHI@1236|Gammaproteobacteria,1XIK3@135619|Oceanospirillales 135619|Oceanospirillales J histidyl-tRNA synthetase hisS - 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_His k141_13443_1 1444309.JAQG01000021_gene1398 3.44e-55 200.0 COG2027@1|root,COG2027@2|Bacteria,1TQFQ@1239|Firmicutes,4HA3X@91061|Bacilli,271XZ@186822|Paenibacillaceae 91061|Bacilli M D-Ala-D-Ala carboxypeptidase 3 (S13) family dacC - 3.4.16.4 ko:K07259 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - Peptidase_S13 k141_34772_1 218284.CCDN010000002_gene2029 1.25e-37 129.0 COG5012@1|root,COG5012@2|Bacteria,1UIKM@1239|Firmicutes,4ISMI@91061|Bacilli,1ZS6Q@1386|Bacillus 91061|Bacilli S cobalamin binding - - - - - - - - - - - - - k141_407_1 1294265.JCM21738_2873 4.16e-49 170.0 COG1283@1|root,COG1283@2|Bacteria,1TP4K@1239|Firmicutes,4HAZ0@91061|Bacilli,1ZBHZ@1386|Bacillus 91061|Bacilli P COG1283 Na phosphate symporter yjbB - - ko:K03324 - - - - ko00000,ko02000 2.A.58.2 - - Na_Pi_cotrans,PhoU k141_407_2 1294265.JCM21738_2872 2.01e-77 237.0 COG5521@1|root,COG5521@2|Bacteria,1V2MC@1239|Firmicutes,4HGIF@91061|Bacilli,1ZBMN@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF1189) yqgB - - - - - - - - - - - DUF1189 k141_12293_2 582744.Msip34_2653 7.73e-12 64.3 COG1278@1|root,COG3326@1|root,COG1278@2|Bacteria,COG3326@2|Bacteria,1N6YM@1224|Proteobacteria,2VQXP@28216|Betaproteobacteria,2KN8X@206350|Nitrosomonadales 206350|Nitrosomonadales K Protein of unknown function (DUF1294) - - - - - - - - - - - - CSD,DUF1294 k141_32321_1 1116375.VEJY3_20441 5.96e-68 220.0 COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,1RMHY@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator - - - ko:K11914 - - - - ko00000,ko02044,ko03000 - - - HTH_8,PAS,PAS_4,Sigma54_activat k141_32321_2 1116375.VEJY3_20446 2.69e-62 208.0 2BXCB@1|root,2Z8QU@2|Bacteria,1MZ0I@1224|Proteobacteria,1RRGR@1236|Gammaproteobacteria 1236|Gammaproteobacteria M 3HB-oligomer hydrolase (3HBOH) - - 3.1.1.22 ko:K07518 ko00650,map00650 - R00048 RC00037,RC00094 ko00000,ko00001,ko01000 - - - 3HBOH k141_1448_1 1042377.AFPJ01000036_gene1263 1.92e-63 198.0 2C4GG@1|root,331DQ@2|Bacteria,1N7QC@1224|Proteobacteria,1SCI3@1236|Gammaproteobacteria,468SZ@72275|Alteromonadaceae 1236|Gammaproteobacteria S Polyribonucleotide nucleotidyltransferase - - - - - - - - - - - - - k141_14543_2 401526.TcarDRAFT_1910 4.8e-24 107.0 COG4753@1|root,COG4963@1|root,COG4753@2|Bacteria,COG4963@2|Bacteria,1UF2S@1239|Firmicutes,4H306@909932|Negativicutes 909932|Negativicutes KTU cheY-homologous receiver domain - - - - - - - - - - - - AAA_31,Response_reg k141_24066_1 1118054.CAGW01000106_gene3684 1.3e-81 258.0 COG1961@1|root,COG1961@2|Bacteria,1TPUG@1239|Firmicutes,4HB3H@91061|Bacilli,26VGC@186822|Paenibacillaceae 91061|Bacilli L Recombinase zinc beta ribbon domain - - - ko:K06400 - - - - ko00000 - - - Recombinase,Resolvase,Zn_ribbon_recom k141_35925_1 218284.CCDN010000005_gene3356 5.15e-120 347.0 COG0861@1|root,COG0861@2|Bacteria,1TQ09@1239|Firmicutes,4HB99@91061|Bacilli,1ZBPQ@1386|Bacillus 91061|Bacilli P COG0861 Membrane protein TerC, possibly involved in tellurium resistance ykoY - - - - - - - - - - - TerC k141_10988_2 2340.JV46_07260 1.1e-07 50.1 COG0198@1|root,COG0198@2|Bacteria,1MZQD@1224|Proteobacteria,1S973@1236|Gammaproteobacteria,1J6C1@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit rplX GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02895 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KOW,ribosomal_L24 k141_15780_1 574375.BAGA_22135 2.51e-90 281.0 COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,4HBZI@91061|Bacilli,1ZFAF@1386|Bacillus 91061|Bacilli E Bacterial extracellular solute-binding proteins, family 5 Middle nikA - - ko:K15584 ko02010,map02010 M00440 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 k141_6375_1 1196031.ALEG01000039_gene1669 7.28e-53 179.0 COG1776@1|root,COG1886@1|root,COG1776@2|Bacteria,COG1886@2|Bacteria,1TPT8@1239|Firmicutes,4HC56@91061|Bacilli,1ZB7S@1386|Bacillus 91061|Bacilli N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation fliY GO:0003674,GO:0003824,GO:0004721,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006935,GO:0008150,GO:0008152,GO:0009605,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0032879,GO:0036211,GO:0040011,GO:0040012,GO:0042221,GO:0042330,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0050896,GO:0051270,GO:0065007,GO:0071704,GO:0140096,GO:1901564,GO:1902021,GO:2000145 - ko:K02417 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 - - CheC,FliMN_C k141_18209_1 935836.JAEL01000029_gene3573 1.92e-62 199.0 COG0344@1|root,COG0344@2|Bacteria,1VAFC@1239|Firmicutes,4HMJZ@91061|Bacilli,1ZHAN@1386|Bacillus 91061|Bacilli I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP plsY1 - 2.3.1.15 ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - G3P_acyltransf k141_34773_1 1121091.AUMP01000003_gene2541 1.13e-24 104.0 COG1961@1|root,COG1961@2|Bacteria,1TPUG@1239|Firmicutes,4HB3H@91061|Bacilli 91061|Bacilli L COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - ko:K06400 - - - - ko00000 - - - Recombinase,Resolvase,Zn_ribbon_recom k141_5058_1 1294265.JCM21738_621 5.31e-89 266.0 COG2894@1|root,COG2894@2|Bacteria,1TP6P@1239|Firmicutes,4HB2F@91061|Bacilli,1ZB5P@1386|Bacillus 91061|Bacilli D Belongs to the ParA family minD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03609 - - - - ko00000,ko03036,ko04812 - - - AAA_31,CbiA k141_5058_2 1294265.JCM21738_622 5.98e-15 69.7 COG0850@1|root,COG0850@2|Bacteria,1VAPC@1239|Firmicutes,4HBTI@91061|Bacilli,1ZDSJ@1386|Bacillus 91061|Bacilli D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization minC GO:0000910,GO:0003674,GO:0004857,GO:0007049,GO:0007105,GO:0008150,GO:0009987,GO:0022402,GO:0030234,GO:0031333,GO:0032271,GO:0032272,GO:0032506,GO:0043086,GO:0043254,GO:0044087,GO:0044092,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0065007,GO:0065009,GO:0098772 - ko:K03610 - - - - ko00000,ko03036,ko04812 - - - MinC_C k141_3949_2 1116375.VEJY3_20386 8.33e-209 589.0 COG0508@1|root,COG0508@2|Bacteria,1MUGY@1224|Proteobacteria,1RXCZ@1236|Gammaproteobacteria,1Y0WE@135623|Vibrionales 135623|Vibrionales C 2-oxoacid dehydrogenases acyltransferase (catalytic domain) - - 2.3.1.12 ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding k141_3949_3 1116375.VEJY3_20381 1.01e-158 462.0 COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,1S02D@1236|Gammaproteobacteria,1Y3B1@135623|Vibrionales 135623|Vibrionales C Dehydrogenase E1 component - - 1.2.4.4 ko:K11381 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 M00036 R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00027,RC00627,RC02743,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh,Transket_pyr,Transketolase_C k141_27570_1 657309.BXY_03080 1.83e-13 76.3 COG2327@1|root,COG2327@2|Bacteria,4P1WZ@976|Bacteroidetes,2FVC7@200643|Bacteroidia 976|Bacteroidetes S Polysaccharide pyruvyl transferase - - - - - - - - - - - - PS_pyruv_trans k141_27570_2 1042377.AFPJ01000055_gene964 6.55e-198 561.0 COG1035@1|root,COG1035@2|Bacteria,1R45V@1224|Proteobacteria,1RSF5@1236|Gammaproteobacteria,46BVY@72275|Alteromonadaceae 1236|Gammaproteobacteria C Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term - - 1.12.98.1 ko:K00441 ko00680,ko01100,ko01120,map00680,map01100,map01120 - R03025 RC02628 ko00000,ko00001,ko01000 - - - FrhB_FdhB_C,FrhB_FdhB_N k141_27570_3 1042377.AFPJ01000055_gene963 8.85e-181 519.0 28MA5@1|root,2ZANY@2|Bacteria,1RIQ2@1224|Proteobacteria,1S60Q@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_27570_4 1348114.OM33_09925 6.03e-100 303.0 COG1216@1|root,COG1216@2|Bacteria,1PHZB@1224|Proteobacteria,1RXIJ@1236|Gammaproteobacteria,2Q55Q@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria S Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 k141_27570_5 1246995.AFR_16000 1.38e-30 123.0 COG1215@1|root,COG1215@2|Bacteria,2GJP7@201174|Actinobacteria,4DD53@85008|Micromonosporales 201174|Actinobacteria M Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 k141_27570_6 1042377.AFPJ01000055_gene959 3.13e-18 83.6 COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,1RPAG@1236|Gammaproteobacteria,465SE@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Non-ribosomal peptide synthetase - - - - - - - - - - - - AMP-binding,AMP-binding_C,Acyl_transf_1,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_12,PP-binding,Thioesterase,ketoacyl-synt k141_24067_1 502025.Hoch_4825 7.08e-26 112.0 COG5000@1|root,COG5000@2|Bacteria,1NU7E@1224|Proteobacteria,42YZ2@68525|delta/epsilon subdivisions,2WTQ1@28221|Deltaproteobacteria 28221|Deltaproteobacteria T Histidine kinase - - 2.7.13.3 ko:K02668,ko:K07709 ko02020,map02020 M00499,M00501 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 - - - HAMP,HATPase_c,HisKA,PAS,PAS_10,PAS_4,PAS_9,sCache_3_2 k141_9801_1 1499967.BAYZ01000157_gene598 1.24e-93 278.0 COG0740@1|root,COG0740@2|Bacteria,2NNPA@2323|unclassified Bacteria 2|Bacteria O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins clpP GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 - - - ko00000,ko00001,ko01000,ko01002 - - - CLP_protease k141_9801_2 977880.RALTA_A1391 2.32e-106 320.0 COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,2VIEU@28216|Betaproteobacteria,1K1CX@119060|Burkholderiaceae 28216|Betaproteobacteria O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP clpX - - ko:K03544 ko04112,map04112 - - - ko00000,ko00001,ko03110 - - - AAA_2,ClpB_D2-small,zf-C4_ClpX k141_20452_1 935836.JAEL01000004_gene2612 1.26e-38 132.0 COG2318@1|root,COG2318@2|Bacteria,1V95A@1239|Firmicutes,4IDNB@91061|Bacilli,1ZCII@1386|Bacillus 91061|Bacilli S DinB superfamily - - - - - - - - - - - - DinB_2 k141_15782_1 218284.CCDN010000006_gene3593 1.07e-52 170.0 COG1845@1|root,COG1845@2|Bacteria,1TQJ1@1239|Firmicutes,4HCWH@91061|Bacilli,1ZDEX@1386|Bacillus 91061|Bacilli C quinol oxidase, subunit qoxC GO:0003674,GO:0003824,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016679,GO:0016682,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.10.3.12 ko:K02828 ko00190,ko01100,map00190,map01100 M00416 R09492 RC00819 ko00000,ko00001,ko00002,ko01000 - - - COX3 k141_15782_2 218284.CCDN010000006_gene3594 1.58e-41 150.0 COG0843@1|root,COG0843@2|Bacteria,1TP2U@1239|Firmicutes,4HA4X@91061|Bacilli,1ZBD5@1386|Bacillus 91061|Bacilli C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B qoxB GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009486,GO:0009987,GO:0015002,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016310,GO:0016491,GO:0016679,GO:0016682,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0034220,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0098655,GO:0098660,GO:0098662,GO:1901135,GO:1901360,GO:1901564,GO:1902600 1.10.3.12 ko:K02827 ko00190,ko01100,map00190,map01100 M00416 R09492 RC00819 ko00000,ko00001,ko00002,ko01000 3.D.4.1 - - COX1 k141_13446_1 42565.FP66_04030 2.87e-95 277.0 COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,1S5WI@1236|Gammaproteobacteria,1XK7A@135619|Oceanospirillales 135619|Oceanospirillales O Belongs to the MsrB Met sulfoxide reductase family msrB - 1.8.4.12 ko:K07305 - - - - ko00000,ko01000 - - - SelR k141_13446_2 42565.FP66_04025 9.48e-06 46.2 COG1161@1|root,COG1161@2|Bacteria,1MV5H@1224|Proteobacteria,1RP79@1236|Gammaproteobacteria,1XIA0@135619|Oceanospirillales 135619|Oceanospirillales S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity rbgA - - ko:K14540 - - - - ko00000,ko03009 - - - MMR_HSR1 k141_14545_1 1453501.JELR01000001_gene2569 2.59e-95 291.0 28HNB@1|root,2Z7WM@2|Bacteria,1MWQ1@1224|Proteobacteria,1RZ55@1236|Gammaproteobacteria,464IB@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_1450_1 1294265.JCM21738_431 1.38e-84 261.0 COG3420@1|root,COG3420@2|Bacteria,1UN63@1239|Firmicutes,4HDJ8@91061|Bacilli,1ZRYJ@1386|Bacillus 91061|Bacilli P Periplasmic copper-binding protein (NosD) nosD - - ko:K07218 - - - - ko00000 - - - NosD k141_12538_1 1294265.JCM21738_5022 6.28e-116 342.0 COG1252@1|root,COG1252@2|Bacteria,1TR6X@1239|Firmicutes,4HA14@91061|Bacilli,1ZAV9@1386|Bacillus 91061|Bacilli C NADH dehydrogenase - - 1.6.99.3 ko:K03885 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - Pyr_redox_2 k141_5254_1 42256.RradSPS_2144 4.88e-90 275.0 COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,2GJB6@201174|Actinobacteria,4CPTD@84995|Rubrobacteria 84995|Rubrobacteria HP UBA THIF-type NAD FAD binding - - 2.7.7.80,2.8.1.11 ko:K21147 ko04122,map04122 - R07459,R07461 RC00043 ko00000,ko00001,ko01000 - - - Rhodanese,ThiF k141_10040_1 218284.CCDN010000001_gene524 1.45e-78 251.0 COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HB1B@91061|Bacilli,1ZC0T@1386|Bacillus 91061|Bacilli T Signal transduction histidine kinase phoR - 2.7.13.3 ko:K07636 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_9,sCache_like k141_20627_1 218284.CCDN010000001_gene202 4.62e-33 117.0 2AQNN@1|root,31FW1@2|Bacteria,1UA6S@1239|Firmicutes,4IKHR@91061|Bacilli,1ZH0V@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_24188_5 1279017.AQYJ01000019_gene1503 1.95e-101 296.0 COG0597@1|root,COG0597@2|Bacteria,1RGV9@1224|Proteobacteria,1S60E@1236|Gammaproteobacteria,467DX@72275|Alteromonadaceae 1236|Gammaproteobacteria MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins lspA - 3.4.23.36 ko:K03101 ko03060,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_A8 k141_19515_1 218284.CCDN010000001_gene1552 5.36e-129 389.0 COG0768@1|root,COG0768@2|Bacteria,1TQHY@1239|Firmicutes,4HAFX@91061|Bacilli,1ZBJM@1386|Bacillus 91061|Bacilli M penicillin-binding protein pbpH - - ko:K21465 ko00550,map00550 - - - ko00000,ko00001,ko01011 - - - PBP_dimer,Transpeptidase k141_18403_1 218284.CCDN010000001_gene1410 8.74e-80 241.0 COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,4HA7D@91061|Bacilli,1ZARN@1386|Bacillus 91061|Bacilli T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - ko:K02483 - - - - ko00000,ko02022 - - - Response_reg,Trans_reg_C k141_36046_1 493475.GARC_4315 6.87e-94 295.0 COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,1RQ8B@1236|Gammaproteobacteria,4666D@72275|Alteromonadaceae 1236|Gammaproteobacteria T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA k141_36046_2 506534.Rhein_2850 0.000152 43.5 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1X00P@135613|Chromatiales 135613|Chromatiales T response regulator receiver - - - - - - - - - - - - HTH_8,Response_reg,Sigma54_activat k141_631_2 1379698.RBG1_1C00001G1062 3.36e-49 176.0 COG1007@1|root,COG1007@2|Bacteria,2NNMY@2323|unclassified Bacteria 2|Bacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoN-1 - 1.6.5.3 ko:K00343 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_M k141_33819_1 1307436.PBF_07271 2.98e-146 415.0 COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,4HAA6@91061|Bacilli,1ZCDY@1386|Bacillus 91061|Bacilli IQ reductase fabG GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - iYO844.BSU15910 adh_short_C2 k141_33819_2 1294265.JCM21738_255 3.1e-113 332.0 COG0331@1|root,COG0331@2|Bacteria,1TPB7@1239|Firmicutes,4HBCU@91061|Bacilli,1ZBGQ@1386|Bacillus 91061|Bacilli I malonyl CoA-acyl carrier protein transacylase fabD - 2.3.1.39 ko:K00645 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082 R01626,R11671 RC00004,RC00039,RC02727 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyl_transf_1 k141_8873_1 1347369.CCAD010000047_gene286 2.46e-107 318.0 COG3239@1|root,COG3239@2|Bacteria,1TP3B@1239|Firmicutes,4H9TS@91061|Bacilli,1ZAYJ@1386|Bacillus 91061|Bacilli I fatty acid desaturase des - 1.14.19.23,1.14.19.45 ko:K10255 ko02020,map02020 - - - ko00000,ko00001,ko01000,ko01004 - - - FA_desaturase k141_34964_1 218284.CCDN010000002_gene2209 2.73e-49 165.0 COG1744@1|root,COG1744@2|Bacteria,1TPEU@1239|Firmicutes,4HBCY@91061|Bacilli,1ZCTZ@1386|Bacillus 91061|Bacilli S ABC transporter substrate-binding protein PnrA-like - - - ko:K07335 - - - - ko00000 - - - Bmp k141_34964_2 218284.CCDN010000002_gene2208 7.66e-76 242.0 COG0840@1|root,COG0840@2|Bacteria,1UVY9@1239|Firmicutes,4HB1T@91061|Bacilli,1ZD8I@1386|Bacillus 91061|Bacilli NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). yvaQ - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal k141_17102_1 626418.bglu_1g33280 7.68e-14 71.2 COG1984@1|root,COG1984@2|Bacteria,1MU9H@1224|Proteobacteria,2VNJE@28216|Betaproteobacteria,1K05Q@119060|Burkholderiaceae 28216|Betaproteobacteria E Allophanate hydrolase kipA - 3.5.1.54 ko:K01457 ko00220,ko00791,ko01100,ko01120,map00220,map00791,map01100,map01120 - R00005 RC02756 ko00000,ko00001,ko01000 - - - CT_A_B k141_17102_2 1042375.AFPL01000008_gene3200 1.46e-57 189.0 COG2049@1|root,COG2049@2|Bacteria,1MWRB@1224|Proteobacteria,1RQIQ@1236|Gammaproteobacteria,466WY@72275|Alteromonadaceae 1236|Gammaproteobacteria E Allophanate hydrolase subunit 1 kipI - - - - - - - - - - - CT_C_D k141_7574_1 935836.JAEL01000126_gene3187 1.33e-24 105.0 COG3276@1|root,COG3276@2|Bacteria,1TPQS@1239|Firmicutes,4HDD5@91061|Bacilli,1ZD2K@1386|Bacillus 91061|Bacilli J Selenocysteine-specific translation elongation factor selB - - ko:K03833 - - - - ko00000,ko03012 - - - GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3 k141_14673_1 218284.CCDN010000004_gene3125 8.39e-150 441.0 COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,4HADT@91061|Bacilli,1ZCKV@1386|Bacillus 91061|Bacilli KT Sigma-54 interaction domain - - - - - - - - - - - - HTH_12,HTH_8,PAS,PAS_9,Sigma54_activat k141_18404_1 1294265.JCM21738_275 2.47e-82 245.0 COG1161@1|root,COG1161@2|Bacteria,1TQGK@1239|Firmicutes,4HA4D@91061|Bacilli,1ZB63@1386|Bacillus 91061|Bacilli S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity rbgA GO:0003674,GO:0003824,GO:0003924,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022613,GO:0042254,GO:0044085,GO:0071840 - ko:K14540 - - - - ko00000,ko03009 - - - MMR_HSR1 k141_18404_2 1294265.JCM21738_276 3.63e-40 139.0 COG0164@1|root,COG0164@2|Bacteria,1V1D6@1239|Firmicutes,4HB7M@91061|Bacilli,1ZB7H@1386|Bacillus 91061|Bacilli L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03470 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_HII k141_31347_1 1279017.AQYJ01000022_gene2699 8.45e-93 284.0 COG0845@1|root,COG0845@2|Bacteria,1NQDN@1224|Proteobacteria,1RRFE@1236|Gammaproteobacteria,4652W@72275|Alteromonadaceae 1236|Gammaproteobacteria M Barrel-sandwich domain of CusB or HlyD membrane-fusion ybjY - - ko:K02005 - - - - ko00000 - - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 k141_10076_2 1192124.LIG30_4871 2.77e-43 152.0 COG0406@1|root,COG0406@2|Bacteria,1QU3R@1224|Proteobacteria,2WH6F@28216|Betaproteobacteria 28216|Betaproteobacteria G alpha-ribazole phosphatase activity - - - - - - - - - - - - - k141_28990_2 1121930.AQXG01000001_gene1127 3.52e-17 79.3 COG0388@1|root,COG0388@2|Bacteria,4NEME@976|Bacteroidetes,1IPIY@117747|Sphingobacteriia 976|Bacteroidetes S PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase pabB - 3.5.1.53,3.5.1.6 ko:K01431,ko:K12251 ko00240,ko00330,ko00410,ko00770,ko00983,ko01100,map00240,map00330,map00410,map00770,map00983,map01100 M00046 R00905,R01152,R04666,R08228 RC00096 ko00000,ko00001,ko00002,ko01000 - - - CN_hydrolase k141_27677_1 218284.CCDN010000005_gene3452 8.07e-70 221.0 COG0477@1|root,COG2814@2|Bacteria,1TRDJ@1239|Firmicutes,4H9Q9@91061|Bacilli,1ZBN7@1386|Bacillus 91061|Bacilli EGP Major facilitator superfamily yuxJ - - - - - - - - - - - MFS_1,Sugar_tr k141_27677_2 218284.CCDN010000005_gene3451 3.07e-288 798.0 COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4HBBB@91061|Bacilli,1ZCKA@1386|Bacillus 91061|Bacilli M Penicillin-binding Protein pbpD - 2.4.1.129,3.4.16.4 ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase k141_4110_1 1279017.AQYJ01000023_gene3170 1.17e-127 380.0 COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,1RM98@1236|Gammaproteobacteria,465ZI@72275|Alteromonadaceae 1236|Gammaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoC GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 ko:K13378 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - iECDH10B_1368.ECDH10B_2448,iECDH1ME8569_1439.ECDH1ME8569_2223,iETEC_1333.ETEC_2421,iEcDH1_1363.EcDH1_1371,iPC815.YPO2553,iUMNK88_1353.UMNK88_2836 Complex1_30kDa,Complex1_49kDa k141_4110_2 323261.Noc_1124 2.32e-50 166.0 COG1905@1|root,COG1905@2|Bacteria,1MWS2@1224|Proteobacteria,1RN4C@1236|Gammaproteobacteria 1236|Gammaproteobacteria C NADH dehydrogenase nuoE - 1.6.5.3 ko:K00334 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - 2Fe-2S_thioredx k141_4110_3 1279017.AQYJ01000023_gene3168 1.31e-240 669.0 COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,1RMUD@1236|Gammaproteobacteria,46546@72275|Alteromonadaceae 1236|Gammaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain nuoF GO:0000166,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0010181,GO:0015980,GO:0016020,GO:0030964,GO:0032553,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0048037,GO:0050662,GO:0051287,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.6.5.3 ko:K00335 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_51K,NADH_4Fe-4S,SLBB k141_4110_4 1279017.AQYJ01000023_gene3167 0.0 995.0 COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,1RMUH@1236|Gammaproteobacteria,464RK@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G) nuoG GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0048037,GO:0050136,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 ko:K00336 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - iECs_1301.ECs3167,iG2583_1286.G2583_2820,iZ_1308.Z3542 Fer2_4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3 k141_4110_5 1279017.AQYJ01000023_gene3166 3.32e-176 497.0 COG1005@1|root,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,1RQE9@1236|Gammaproteobacteria,4643U@72275|Alteromonadaceae 1236|Gammaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone nuoH - 1.6.5.3 ko:K00337 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - NADHdh k141_24189_1 218284.CCDN010000001_gene153 1.32e-156 448.0 COG0508@1|root,COG0508@2|Bacteria,1TR5N@1239|Firmicutes,4HA7A@91061|Bacilli,1ZAQR@1386|Bacillus 91061|Bacilli C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex pdhC - 2.3.1.12 ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding k141_5293_1 1294265.JCM21738_5393 1.79e-148 437.0 COG2183@1|root,COG2183@2|Bacteria,1TPFE@1239|Firmicutes,4HAGY@91061|Bacilli,1ZC3T@1386|Bacillus 91061|Bacilli K COG2183 Transcriptional accessory protein tex - - ko:K06959 - - - - ko00000 - - - HHH_3,S1,Tex_N,Tex_YqgF k141_14674_1 655815.ZPR_2938 1.81e-85 270.0 COG3250@1|root,COG3250@2|Bacteria,4NESZ@976|Bacteroidetes,1HXMX@117743|Flavobacteriia 976|Bacteroidetes G Belongs to the glycosyl hydrolase 2 family - - 3.2.1.31 ko:K01195 ko00040,ko00531,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00531,map00860,map00944,map00983,map01100,map01110,map04142 M00014,M00076,M00077,M00078,M00129 R01478,R04979,R07818,R08127,R08260,R10830 RC00055,RC00171,RC00529,RC00530,RC00714,RC01251 ko00000,ko00001,ko00002,ko01000 - - - Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N k141_34965_1 266779.Meso_0396 2.64e-47 167.0 COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,2TQKD@28211|Alphaproteobacteria,43IYC@69277|Phyllobacteriaceae 28211|Alphaproteobacteria E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids alr - 5.1.1.1 ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 - R00401 RC00285 ko00000,ko00001,ko01000,ko01011 - - - Ala_racemase_C,Ala_racemase_N k141_1607_2 1385514.N782_06500 7.11e-34 129.0 COG1132@1|root,COG1132@2|Bacteria,1TSY4@1239|Firmicutes,4HAJQ@91061|Bacilli,2Y8Z4@289201|Pontibacillus 91061|Bacilli V Multidrug ABC transporter permease lmrA - 3.6.3.44 ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 M00700 - - ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 3.A.1.106,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.123,3.A.1.21 - - ABC_membrane,ABC_tran k141_15902_1 1116375.VEJY3_18406 0.0 951.0 COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,1RPNE@1236|Gammaproteobacteria,1Y04N@135623|Vibrionales 135623|Vibrionales I AMP-binding enzyme - - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding k141_10077_1 1122239.AULS01000002_gene968 3.41e-12 70.9 COG1228@1|root,COG1228@2|Bacteria,2IISK@201174|Actinobacteria,4FNWF@85023|Microbacteriaceae 201174|Actinobacteria Q amidohydrolase - - - - - - - - - - - - Amidohydro_1 k141_633_1 1340434.AXVA01000002_gene1175 2.58e-103 316.0 COG1109@1|root,COG1109@2|Bacteria,1TP2N@1239|Firmicutes,4HADU@91061|Bacilli,1ZBEM@1386|Bacillus 91061|Bacilli G Phosphoglucomutase pgcA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 5.4.2.2 ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00549 R00959,R01057,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV k141_8874_1 42565.FP66_03450 1.06e-138 402.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,1RNAM@1236|Gammaproteobacteria,1XHAI@135619|Oceanospirillales 135619|Oceanospirillales G COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - - - - - - - - - - DctM k141_8874_2 42565.FP66_03445 2.12e-44 146.0 COG0589@1|root,COG0589@2|Bacteria,1RINB@1224|Proteobacteria,1S68P@1236|Gammaproteobacteria,1XJY2@135619|Oceanospirillales 135619|Oceanospirillales T Universal stress protein - - - - - - - - - - - - Usp k141_28991_1 561175.KB894099_gene5133 9.33e-22 91.7 COG0087@1|root,COG0087@2|Bacteria,2GJXT@201174|Actinobacteria,4EIEQ@85012|Streptosporangiales 201174|Actinobacteria J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit rplC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - ko:K02906 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L3 k141_28991_2 1150469.RSPPHO_01221 2.75e-43 143.0 COG0051@1|root,COG0051@2|Bacteria,1RGWF@1224|Proteobacteria,2U95D@28211|Alphaproteobacteria,2JST1@204441|Rhodospirillales 204441|Rhodospirillales J Involved in the binding of tRNA to the ribosomes rpsJ - - ko:K02946 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S10 k141_34966_2 997296.PB1_17254 1.89e-16 75.1 COG0275@1|root,COG0275@2|Bacteria,1UHPG@1239|Firmicutes,4IS5B@91061|Bacilli,1ZFKV@1386|Bacillus 91061|Bacilli M Putative rRNA methylase ytqB - - - - - - - - - - - rRNA_methylase k141_10078_1 1453501.JELR01000005_gene1747 1.05e-25 96.3 COG3139@1|root,COG3139@2|Bacteria,1N7ZT@1224|Proteobacteria,1SC7K@1236|Gammaproteobacteria,4696A@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF1315) - - - ko:K09916 - - - - ko00000 - - - DUF1315 k141_5294_1 218284.CCDN010000007_gene3956 1.18e-137 394.0 COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,4HA59@91061|Bacilli,1ZAYV@1386|Bacillus 91061|Bacilli I Dehydrogenase mmgB - 1.1.1.157 ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 - R01976,R05576,R06941 RC00029,RC00117 ko00000,ko00001,ko01000 - - - 3HCDH,3HCDH_N k141_32445_1 1042377.AFPJ01000005_gene2462 3.03e-200 565.0 COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,1RMR6@1236|Gammaproteobacteria,4642Y@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Tripartite ATP-independent periplasmic transporter, DctM component gtrB - - - - - - - - - - - DctM k141_32445_2 1265313.HRUBRA_02258 1.51e-54 179.0 COG4665@1|root,COG4665@2|Bacteria,1RHBW@1224|Proteobacteria,1S5Y0@1236|Gammaproteobacteria,1J63A@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria Q transport system, small permease component gtrA - - - - - - - - - - - DctQ k141_4111_1 218284.CCDN010000001_gene1010 1.63e-35 129.0 COG0454@1|root,COG0456@2|Bacteria,1V2SN@1239|Firmicutes,4HGC0@91061|Bacilli,1ZD79@1386|Bacillus 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10,Acetyltransf_7 k141_4111_2 218284.CCDN010000001_gene1009 1.83e-60 190.0 COG0406@1|root,COG0406@2|Bacteria,1V7F8@1239|Firmicutes,4HIR1@91061|Bacilli,1ZHAP@1386|Bacillus 91061|Bacilli G Phosphoglycerate mutase gpmA1 - 5.4.2.11 ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - His_Phos_1 k141_21883_2 1453501.JELR01000001_gene1870 5.07e-205 573.0 COG3268@1|root,COG3268@2|Bacteria,1MVI3@1224|Proteobacteria,1RS16@1236|Gammaproteobacteria,46DGK@72275|Alteromonadaceae 1236|Gammaproteobacteria S Saccharopine dehydrogenase NADP binding domain lys - - - - - - - - - - - Sacchrp_dh_NADP k141_1608_1 1397528.Q671_06595 4.46e-31 117.0 COG0462@1|root,COG0462@2|Bacteria,1MUV7@1224|Proteobacteria,1RY55@1236|Gammaproteobacteria,1XHTW@135619|Oceanospirillales 135619|Oceanospirillales EF Belongs to the ribose-phosphate pyrophosphokinase family - - 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - Pribosyltran,Pribosyltran_N k141_1608_2 42565.FP66_05630 1.5e-89 276.0 COG0213@1|root,COG0213@2|Bacteria,1MV3H@1224|Proteobacteria,1RPTG@1236|Gammaproteobacteria,1XHR2@135619|Oceanospirillales 135619|Oceanospirillales F The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis - - 2.4.2.4 ko:K00758 ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219 - R01570,R02484,R08222,R08230 RC00063 ko00000,ko00001,ko01000 - - - Glycos_trans_3N,Glycos_transf_3,PYNP_C k141_14675_2 218284.CCDN010000005_gene3487 5.9e-97 287.0 COG4821@1|root,COG4821@2|Bacteria,1TQS7@1239|Firmicutes,4HCR4@91061|Bacilli,1ZAP1@1386|Bacillus 91061|Bacilli S carbohydrate derivative metabolic process - - - - - - - - - - - - SIS_2 k141_15903_1 626887.J057_08841 1.05e-63 206.0 COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,1RPSV@1236|Gammaproteobacteria,465UN@72275|Alteromonadaceae 1236|Gammaproteobacteria F Belongs to the ATCase OTCase family pyrB GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N k141_15903_2 98439.AJLL01000010_gene1342 3.29e-10 59.3 COG2065@1|root,COG2065@2|Bacteria,1G4ZI@1117|Cyanobacteria,1JGY8@1189|Stigonemataceae 1117|Cyanobacteria F Phosphoribosyl transferase domain pyrR - 2.4.2.9 ko:K02825 ko00240,ko01100,map00240,map01100 - R00966 RC00063 ko00000,ko00001,ko01000,ko03000 - - - Pribosyltran k141_19517_1 1453501.JELR01000001_gene2181 3.76e-85 256.0 COG3749@1|root,COG3749@2|Bacteria,1RJR9@1224|Proteobacteria,1S64S@1236|Gammaproteobacteria,46803@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - DUF934 k141_19517_2 1279017.AQYJ01000029_gene3708 6.18e-115 344.0 COG0155@1|root,COG0155@2|Bacteria,1MVVB@1224|Proteobacteria,1RMFH@1236|Gammaproteobacteria,465NM@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG0155 Sulfite reductase, beta subunit (hemoprotein) cysI - 1.8.1.2 ko:K00381 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00176 R00858 RC00065 ko00000,ko00001,ko00002,ko01000 - - - NIR_SIR,NIR_SIR_ferr k141_20651_1 768066.HELO_3303 1.6e-23 97.1 COG2133@1|root,COG2133@2|Bacteria,1N3PW@1224|Proteobacteria,1S9RZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria G pyrroloquinoline quinone binding - - - - - - - - - - - - - k141_10079_1 42565.FP66_06060 1.46e-58 183.0 COG3189@1|root,COG3189@2|Bacteria,1MZ7H@1224|Proteobacteria,1S9PQ@1236|Gammaproteobacteria,1XPVZ@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function, DUF488 - - - - - - - - - - - - DUF488 k141_635_1 935836.JAEL01000014_gene2050 2.07e-113 333.0 COG0584@1|root,COG0584@2|Bacteria,1UBR3@1239|Firmicutes,4H9Z9@91061|Bacilli,1ZD0X@1386|Bacillus 91061|Bacilli C Glycerophosphoryl diester phosphodiesterase family - - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - GDPD k141_15904_1 1042377.AFPJ01000030_gene493 1.16e-73 227.0 COG1262@1|root,COG1262@2|Bacteria,1Q227@1224|Proteobacteria,1RQEK@1236|Gammaproteobacteria,467FP@72275|Alteromonadaceae 1236|Gammaproteobacteria S SapC - - - - - - - - - - - - SapC k141_8877_1 465541.ATCJ01000005_gene2096 3.77e-49 168.0 COG1230@1|root,COG1230@2|Bacteria,2GMRZ@201174|Actinobacteria 201174|Actinobacteria P cation diffusion facilitator family transporter - - - ko:K16264 - - - - ko00000,ko02000 2.A.4.1 - - Cation_efflux k141_31349_1 218284.CCDN010000008_gene4244 2.68e-127 365.0 COG0517@1|root,COG0517@2|Bacteria,1V0XU@1239|Firmicutes,4HD12@91061|Bacilli,1ZBNZ@1386|Bacillus 91061|Bacilli S Acetoin utilization protein AcuB acuB - - ko:K04767 - - - - ko00000 - - - ACT,CBS k141_31361_1 379066.GAU_2451 1.01e-156 456.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1ZTG9@142182|Gemmatimonadetes 142182|Gemmatimonadetes F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth guaB - 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 - - - CBS,IMPDH k141_10105_1 675816.VIA_000754 1.55e-202 606.0 COG0210@1|root,COG0515@1|root,COG1112@1|root,COG0210@2|Bacteria,COG0515@2|Bacteria,COG1112@2|Bacteria,1MWW9@1224|Proteobacteria,1RP8R@1236|Gammaproteobacteria,1XVTF@135623|Vibrionales 135623|Vibrionales L AAA domain - - - - - - - - - - - - AAA_11,AAA_12,NERD k141_5328_1 1340493.JNIF01000004_gene1045 1.57e-46 164.0 COG2972@1|root,COG2972@2|Bacteria,3Y80P@57723|Acidobacteria 57723|Acidobacteria T Histidine kinase - - - - - - - - - - - - His_kinase k141_12578_1 1453501.JELR01000001_gene2060 9.02e-28 103.0 COG1555@1|root,COG1555@2|Bacteria,1N6Q3@1224|Proteobacteria,1SC7U@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Competence protein ComEA comEA GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 - ko:K02237 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - HHH_3 k141_12578_2 1577887.JSYG01000026_gene360 3.19e-21 90.1 COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,1RNJR@1236|Gammaproteobacteria,2JE1J@204037|Dickeya 1236|Gammaproteobacteria F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) pyrF GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 ko:K01591 ko00240,ko01100,map00240,map01100 M00051 R00965 RC00409 ko00000,ko00001,ko00002,ko01000 - - iECO103_1326.ECO103_1444,iECSF_1327.ECSF_1264,iSFV_1184.SFV_1294,iSF_1195.SF1285,iSFxv_1172.SFxv_1457,iS_1188.S1368,ic_1306.c1750 OMPdecase k141_21899_1 1347086.CCBA010000026_gene3218 4.11e-120 351.0 COG0334@1|root,COG0334@2|Bacteria,1TQU2@1239|Firmicutes,4HAB2@91061|Bacilli,1ZB55@1386|Bacillus 91061|Bacilli E Belongs to the Glu Leu Phe Val dehydrogenases family ldh - 1.4.1.9 ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 - R01088,R01434,R02196 RC00006,RC00036 ko00000,ko00001,ko01000 - - - ELFV_dehydrog,ELFV_dehydrog_N k141_1626_1 1196031.ALEG01000064_gene3609 3.8e-132 391.0 COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,4H9VY@91061|Bacilli,1ZCDT@1386|Bacillus 91061|Bacilli G Belongs to the pyruvate kinase family pyk GO:0001871,GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0030246,GO:0030247,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:2001065 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - PEP-utilizers,PK,PK_C k141_27695_1 218284.CCDN010000006_gene3635 3.03e-133 382.0 COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,4HA4N@91061|Bacilli,1ZBDJ@1386|Bacillus 91061|Bacilli C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family trxB - 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Pyr_redox_2 k141_32471_1 42565.FP66_08960 2.91e-107 321.0 COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RMFF@1236|Gammaproteobacteria,1XH5E@135619|Oceanospirillales 135619|Oceanospirillales C 2-oxoglutarate dehydrogenase complex lpdG - 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyr_redox_2,Pyr_redox_dim k141_29000_1 218284.CCDN010000002_gene2062 1.19e-97 295.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HBTP@91061|Bacilli,1ZATT@1386|Bacillus 91061|Bacilli I acyl-CoA dehydrogenase - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_2,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_24229_1 1116375.VEJY3_04330 4.9e-168 475.0 COG0031@1|root,COG0031@2|Bacteria,1MUR6@1224|Proteobacteria,1RMS1@1236|Gammaproteobacteria,1XUZT@135623|Vibrionales 135623|Vibrionales E Cysteine synthase - - 2.5.1.47 ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03601,R04859 RC00020,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 - - - PALP k141_14691_1 218284.CCDN010000009_gene4310 1.47e-43 159.0 COG1289@1|root,COG1289@2|Bacteria,1U18W@1239|Firmicutes,4IJPB@91061|Bacilli,1ZDV7@1386|Bacillus 91061|Bacilli S Fusaric acid resistance protein-like - - - - - - - - - - - - FUSC,FUSC_2 k141_15923_1 218284.CCDN010000001_gene953 3.17e-105 311.0 COG3854@1|root,COG3854@2|Bacteria,1TQ23@1239|Firmicutes,4HA2K@91061|Bacilli,1ZAWB@1386|Bacillus 91061|Bacilli S stage III sporulation protein AA spoIIIAA - - ko:K06390 - - - - ko00000 - - - AAA,T2SSE k141_19543_1 42565.FP66_14755 4.52e-101 300.0 COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,1RMQ8@1236|Gammaproteobacteria,1XI0C@135619|Oceanospirillales 135619|Oceanospirillales H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps hemC - 2.5.1.61 ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00084 RC02317 ko00000,ko00001,ko00002,ko01000 - - - Porphobil_deam,Porphobil_deamC k141_12579_1 218284.CCDN010000001_gene477 3.39e-78 239.0 COG0494@1|root,COG0494@2|Bacteria,1UI6C@1239|Firmicutes,4HI3F@91061|Bacilli,1ZQ2N@1386|Bacillus 91061|Bacilli L NUDIX domain - - - - - - - - - - - - NUDIX k141_29001_1 1121459.AQXE01000011_gene2407 3.06e-13 73.6 COG0697@1|root,COG0697@2|Bacteria,1R7CJ@1224|Proteobacteria,43AZY@68525|delta/epsilon subdivisions,2WU86@28221|Deltaproteobacteria,2M9VN@213115|Desulfovibrionales 28221|Deltaproteobacteria EG EamA-like transporter family - - - - - - - - - - - - EamA k141_4137_2 563008.HMPREF0665_00821 4.16e-39 145.0 COG2204@1|root,COG2204@2|Bacteria,4NE72@976|Bacteroidetes,2FMZ3@200643|Bacteroidia 976|Bacteroidetes T PglZ domain protein porX - - - - - - - - - - - PglZ,Response_reg k141_23202_1 1232683.ADIMK_3344 1.07e-71 228.0 COG2114@1|root,COG2114@2|Bacteria,1QWNC@1224|Proteobacteria,1S3UK@1236|Gammaproteobacteria,468QZ@72275|Alteromonadaceae 1236|Gammaproteobacteria T Adenylyl- / guanylyl cyclase, catalytic domain - - 4.6.1.1,4.6.1.2 ko:K01768,ko:K01769 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_cyc k141_17269_14 1042377.AFPJ01000036_gene1281 3.99e-63 194.0 COG1544@1|root,COG1544@2|Bacteria,1N4NM@1224|Proteobacteria,1T5IS@1236|Gammaproteobacteria,46BPH@72275|Alteromonadaceae 1236|Gammaproteobacteria J Sigma 54 modulation protein / S30EA ribosomal protein - - - - - - - - - - - - Ribosomal_S30AE k141_17269_15 1279017.AQYJ01000029_gene3437 6.58e-84 264.0 COG1196@1|root,COG1196@2|Bacteria,1NPJ3@1224|Proteobacteria,1SGPQ@1236|Gammaproteobacteria,46C3R@72275|Alteromonadaceae 1236|Gammaproteobacteria D nuclear chromosome segregation - - - - - - - - - - - - - k141_17269_16 717606.PaecuDRAFT_2573 1.84e-05 51.6 COG1514@1|root,COG1514@2|Bacteria,1VEU2@1239|Firmicutes,4HPRP@91061|Bacilli,26YZK@186822|Paenibacillaceae 91061|Bacilli J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester ytlP - 3.1.4.58 ko:K01975 - - - - ko00000,ko01000,ko03016 - - - LigT_PEase k141_17269_17 1279017.AQYJ01000029_gene3439 4.95e-89 263.0 COG0071@1|root,COG0071@2|Bacteria,1RH2X@1224|Proteobacteria,1S6WS@1236|Gammaproteobacteria,466S8@72275|Alteromonadaceae 1236|Gammaproteobacteria O Belongs to the small heat shock protein (HSP20) family ibpA GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0050896 - ko:K04080 - - - - ko00000,ko03110 - - - HSP20 k141_17269_18 1279017.AQYJ01000029_gene3440 6.25e-99 293.0 COG2227@1|root,COG2227@2|Bacteria,1R9ZR@1224|Proteobacteria,1S27B@1236|Gammaproteobacteria,4672C@72275|Alteromonadaceae 1236|Gammaproteobacteria H Methyltransferase domain - - - - - - - - - - - - Methyltransf_23 k141_17269_19 1279017.AQYJ01000029_gene3441 1.07e-201 563.0 COG4977@1|root,COG4977@2|Bacteria,1MUDK@1224|Proteobacteria,1RP9W@1236|Gammaproteobacteria,464RD@72275|Alteromonadaceae 1236|Gammaproteobacteria K DJ-1/PfpI family - - - - - - - - - - - - DJ-1_PfpI,HTH_18 k141_17269_20 1042377.AFPJ01000036_gene1287 0.0 987.0 COG0304@1|root,COG0304@2|Bacteria,1MV67@1224|Proteobacteria,1RMXJ@1236|Gammaproteobacteria,4660E@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ Beta-ketoacyl synthase, C-terminal domain - - 2.3.1.180 ko:K18473 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt k141_1760_2 223926.28807884 2.47e-152 429.0 COG0745@1|root,COG0745@2|Bacteria,1MVCB@1224|Proteobacteria,1RMW7@1236|Gammaproteobacteria,1XSZ6@135623|Vibrionales 135623|Vibrionales K COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain cpxR - - ko:K07662 ko01503,ko02020,map01503,map02020 M00447,M00727,M00728 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C k141_1760_3 1116375.VEJY3_14530 1.01e-97 286.0 COG3678@1|root,COG3678@2|Bacteria,1RBDH@1224|Proteobacteria,1S2DT@1236|Gammaproteobacteria,1XWIC@135623|Vibrionales 135623|Vibrionales NPTU COG3678 P pilus assembly Cpx signaling pathway, periplasmic inhibitor zinc-resistance associated protein cpxP - - ko:K06006 - - - - ko00000,ko03110 - - - LTXXQ k141_1760_4 1219077.VAZ01S_053_00260 1.65e-180 506.0 COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,1RNS2@1236|Gammaproteobacteria,1XSMN@135623|Vibrionales 135623|Vibrionales P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family fieF - - ko:K13283 - - - - ko00000,ko02000 2.A.4.7.1 - - Cation_efflux,ZT_dimer k141_1760_5 223926.28807881 7.97e-224 617.0 COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,1RMVY@1236|Gammaproteobacteria,1XTJ3@135623|Vibrionales 135623|Vibrionales F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis pfkA GO:0003674,GO:0003824,GO:0003872,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008443,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019200,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046835,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0061615,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.11 ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 M00001,M00345 R00756,R03236,R03237,R03238,R03239,R04779 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 - - - PFK k141_1760_6 1116375.VEJY3_14515 9.29e-294 806.0 COG0534@1|root,COG0534@2|Bacteria,1MVRV@1224|Proteobacteria,1RRDQ@1236|Gammaproteobacteria,1XTD2@135623|Vibrionales 135623|Vibrionales V Na driven multidrug efflux pump - - - - - - - - - - - - MatE k141_1760_7 1280001.BAOA01000011_gene4265 1.09e-59 184.0 COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,1S8YR@1236|Gammaproteobacteria,1XXUS@135623|Vibrionales 135623|Vibrionales O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter groS GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - ko:K04078 - - - - ko00000,ko03029,ko03110 - - - Cpn10 k141_2983_1 1294265.JCM21738_4768 5.43e-113 326.0 COG0235@1|root,COG0235@2|Bacteria,1TT62@1239|Firmicutes,4HHI6@91061|Bacilli,1ZCA2@1386|Bacillus 91061|Bacilli E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) mtnB - 3.1.3.87,4.2.1.109 ko:K08964,ko:K08966 ko00270,ko01100,map00270,map01100 M00034 R07392,R07394 RC01939,RC02074 ko00000,ko00001,ko00002,ko01000 - - - Aldolase_II k141_2983_2 1294265.JCM21738_4767 3.15e-49 161.0 COG4359@1|root,COG4359@2|Bacteria,1TSZ9@1239|Firmicutes,4H9ZE@91061|Bacilli,1ZBXD@1386|Bacillus 91061|Bacilli E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene) mtnX - 3.1.3.87 ko:K08966 ko00270,ko01100,map00270,map01100 M00034 R07394 RC02074 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU13600 HAD k141_6688_1 218284.CCDN010000006_gene3594 4.62e-248 694.0 COG0843@1|root,COG0843@2|Bacteria,1TP2U@1239|Firmicutes,4HA4X@91061|Bacilli,1ZBD5@1386|Bacillus 91061|Bacilli C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B qoxB GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009486,GO:0009987,GO:0015002,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016310,GO:0016491,GO:0016679,GO:0016682,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0034220,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0098655,GO:0098660,GO:0098662,GO:1901135,GO:1901360,GO:1901564,GO:1902600 1.10.3.12 ko:K02827 ko00190,ko01100,map00190,map01100 M00416 R09492 RC00819 ko00000,ko00001,ko00002,ko01000 3.D.4.1 - - COX1 k141_10355_1 1042377.AFPJ01000036_gene1137 1.15e-111 353.0 COG1629@1|root,COG1629@2|Bacteria,1MVSG@1224|Proteobacteria,1RS33@1236|Gammaproteobacteria,46A68@72275|Alteromonadaceae 1236|Gammaproteobacteria P Carboxypeptidase regulatory-like domain - - - - - - - - - - - - CarboxypepD_reg k141_7735_1 218284.CCDN010000001_gene1962 1.9e-38 137.0 2DB72@1|root,2Z7JI@2|Bacteria,1UR4B@1239|Firmicutes,4HCE4@91061|Bacilli,1ZC8T@1386|Bacillus 91061|Bacilli S Putative amidase domain yhbB - - - - - - - - - - - Amidase_6 k141_5589_1 1042377.AFPJ01000034_gene2352 8.67e-05 43.9 COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,1RP1N@1236|Gammaproteobacteria,464MJ@72275|Alteromonadaceae 1236|Gammaproteobacteria S LemA family lemA - - ko:K03744 - - - - ko00000 - - - LemA k141_5589_2 1042377.AFPJ01000034_gene2353 1.35e-228 636.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RM93@1236|Gammaproteobacteria,464E8@72275|Alteromonadaceae 1236|Gammaproteobacteria I Belongs to the thiolase family atoB - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - iJN746.PP_2215 Thiolase_C,Thiolase_N k141_32667_1 42565.FP66_03005 2.1e-80 248.0 COG4663@1|root,COG4663@2|Bacteria,1R53Z@1224|Proteobacteria,1SN4E@1236|Gammaproteobacteria,1XP6R@135619|Oceanospirillales 135619|Oceanospirillales Q Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - - - - - - - - - - DctP k141_24480_1 502025.Hoch_2529 1.82e-50 181.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2YXGU@29|Myxococcales 28221|Deltaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran k141_35252_1 1087481.AGFX01000041_gene1031 8.2e-16 76.6 2DPM4@1|root,332KY@2|Bacteria,1VHK3@1239|Firmicutes,4HQHC@91061|Bacilli,26R5V@186822|Paenibacillaceae 91061|Bacilli S Pilus assembly protein TadE - - - - - - - - - - - - TadE k141_35252_2 1218173.BALCAV_0213140 9.25e-21 83.6 2DST6@1|root,33HC5@2|Bacteria,1VKR1@1239|Firmicutes,4HRER@91061|Bacilli,1ZKWK@1386|Bacillus 91061|Bacilli S Putative Flagellin, Flp1-like, domain - - - - - - - - - - - - Flp1_like k141_35252_3 171693.BN988_00241 3.5e-24 97.8 COG2064@1|root,COG2064@2|Bacteria,1V2C3@1239|Firmicutes,4HJBH@91061|Bacilli 91061|Bacilli NU type II secretion - - - ko:K12511 - - - - ko00000,ko02044 - - - T2SSF k141_22058_1 1034347.CAHJ01000040_gene4516 9.51e-82 256.0 COG4109@1|root,COG4109@2|Bacteria,1TPU6@1239|Firmicutes,4HB62@91061|Bacilli,1ZB1Q@1386|Bacillus 91061|Bacilli K transcriptional regulator containing CBS domains ytoI - - - - - - - - - - - 4HBT,CBS,DRTGG,GntR,HTH_24 k141_27125_2 1116375.VEJY3_11415 2.85e-95 279.0 COG3088@1|root,COG3088@2|Bacteria,1MZZ5@1224|Proteobacteria,1S9DV@1236|Gammaproteobacteria,1XWZ0@135623|Vibrionales 135623|Vibrionales P subunit of a heme lyase ccmH - - ko:K02200 - - - - ko00000 - - - CcmH k141_27125_3 1116375.VEJY3_11420 5.63e-129 366.0 COG0526@1|root,COG0526@2|Bacteria,1RI3N@1224|Proteobacteria,1S5YV@1236|Gammaproteobacteria,1XUQ2@135623|Vibrionales 135623|Vibrionales CO Thiol disulfide interchange protein dsbE GO:0003674,GO:0003756,GO:0003824,GO:0008150,GO:0009987,GO:0016043,GO:0016853,GO:0016860,GO:0016864,GO:0017004,GO:0022607,GO:0034622,GO:0043933,GO:0044085,GO:0065003,GO:0071840,GO:0140096 - ko:K02199 - - - - ko00000,ko03110 - - - Redoxin k141_27125_4 1116375.VEJY3_11425 1.48e-172 498.0 COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,1RMY5@1236|Gammaproteobacteria,1XTPD@135623|Vibrionales 135623|Vibrionales O Cytochrome c-type biogenesis protein ccmF ccmF - - ko:K02198 - - - - ko00000,ko02000 9.B.14.1 - - CcmF_C,Cytochrom_C_asm k141_19756_1 1453501.JELR01000001_gene1992 8.48e-106 335.0 COG0642@1|root,COG3437@1|root,COG2205@2|Bacteria,COG3437@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,464QT@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0642 Signal transduction histidine kinase barA GO:0000155,GO:0000160,GO:0000302,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009636,GO:0009927,GO:0009987,GO:0010033,GO:0010035,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0035556,GO:0036211,GO:0042221,GO:0042493,GO:0042542,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046677,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0070887,GO:0071310,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901700 2.7.13.3 ko:K07678 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 M00475 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - DUF2222,HAMP,HATPase_c,HisKA,Hpt,Response_reg k141_23422_1 1042377.AFPJ01000030_gene460 2.6e-10 61.2 COG5373@1|root,COG5373@2|Bacteria,1N08V@1224|Proteobacteria,1RTF0@1236|Gammaproteobacteria,46626@72275|Alteromonadaceae 1236|Gammaproteobacteria S Predicted membrane protein (DUF2339) - - - - - - - - - - - - DUF2339 k141_23422_2 1042377.AFPJ01000030_gene461 4.86e-66 204.0 COG2802@1|root,COG2802@2|Bacteria,1NV9N@1224|Proteobacteria,1T15C@1236|Gammaproteobacteria,46D1P@72275|Alteromonadaceae 1236|Gammaproteobacteria S ATP-dependent protease La (LON) substrate-binding domain - - - ko:K07157 - - - - ko00000 - - - LON_substr_bdg k141_13986_1 218284.CCDN010000010_gene4394 4.07e-219 625.0 COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HACY@91061|Bacilli,1ZB4C@1386|Bacillus 91061|Bacilli O Belongs to the ClpA ClpB family clpC GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 - ko:K03696 ko01100,map01100 - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N,UVR k141_32668_1 42565.FP66_15015 1.54e-109 330.0 COG1226@1|root,COG4651@1|root,COG1226@2|Bacteria,COG4651@2|Bacteria,1MV34@1224|Proteobacteria,1RNH4@1236|Gammaproteobacteria,1XHDV@135619|Oceanospirillales 135619|Oceanospirillales P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family - - - - - - - - - - - - Na_H_Exchanger,TrkA_N k141_34014_1 1173029.JH980292_gene3315 7.93e-26 103.0 COG0604@1|root,COG0604@2|Bacteria,1FZW8@1117|Cyanobacteria,1H6ZN@1150|Oscillatoriales 1117|Cyanobacteria C COG0604 NADPH quinone reductase and related Zn-dependent - - 1.6.5.5 ko:K00344 - - - - ko00000,ko01000 - - - ADH_N,ADH_zinc_N_2 k141_10356_1 243159.AFE_1817 5.89e-18 85.5 COG4424@1|root,COG4424@2|Bacteria,1N77D@1224|Proteobacteria,1SB49@1236|Gammaproteobacteria,2NCGP@225057|Acidithiobacillales 225057|Acidithiobacillales S Sulfotransferase domain - - - - - - - - - - - - Sulfotransfer_3 k141_14851_1 357804.Ping_3593 6.22e-67 211.0 COG1338@1|root,COG1338@2|Bacteria,1MVBU@1224|Proteobacteria,1RMYH@1236|Gammaproteobacteria,2QHZQ@267894|Psychromonadaceae 1236|Gammaproteobacteria N Plays a role in the flagellum-specific transport system fliP - - ko:K02419 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - FliP k141_14851_2 1117314.PCIT_04023 2.69e-25 97.1 COG1987@1|root,COG1987@2|Bacteria,1N73W@1224|Proteobacteria,1SCBG@1236|Gammaproteobacteria,2Q2ZA@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria N Role in flagellar biosynthesis fliQ - - ko:K02420 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - Bac_export_3 k141_14851_3 1517681.HW45_22430 1.01e-105 313.0 COG1684@1|root,COG1684@2|Bacteria,1RCGV@1224|Proteobacteria,1S2MW@1236|Gammaproteobacteria,1XVTR@135623|Vibrionales 1236|Gammaproteobacteria N Role in flagellar biosynthesis - - - ko:K02421 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - Bac_export_1 k141_14851_4 1517681.HW45_22425 2.74e-125 372.0 COG1377@1|root,COG1377@2|Bacteria,1MUWI@1224|Proteobacteria,1RMHA@1236|Gammaproteobacteria,1XUUD@135623|Vibrionales 135623|Vibrionales N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin - - - ko:K02401 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - Bac_export_2 k141_14851_6 754436.JCM19237_3307 4.11e-173 491.0 COG0443@1|root,COG0443@2|Bacteria,1R4I4@1224|Proteobacteria,1RRY4@1236|Gammaproteobacteria,1XZZI@135623|Vibrionales 135623|Vibrionales O StbA protein - - - ko:K18640 - - - - ko00000,ko04812 - - - StbA k141_14851_7 1116375.VEJY3_13170 0.0 1590.0 COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,1RNW3@1236|Gammaproteobacteria,1XTI0@135623|Vibrionales 135623|Vibrionales L that it carries out the mismatch recognition step. This protein has a weak ATPase activity mutS GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K03555 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V k141_14851_8 1116375.VEJY3_13175 8.43e-216 598.0 COG0568@1|root,COG0568@2|Bacteria,1MUDI@1224|Proteobacteria,1RN8V@1236|Gammaproteobacteria,1XSUN@135623|Vibrionales 135623|Vibrionales K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released rpoS - - ko:K03087 ko02026,ko05111,map02026,map05111 - - - ko00000,ko00001,ko03021 - - - Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 k141_14851_9 674977.VMC_08020 4.4e-172 486.0 COG1388@1|root,COG4942@1|root,COG1388@2|Bacteria,COG4942@2|Bacteria,1RD24@1224|Proteobacteria,1RR11@1236|Gammaproteobacteria,1XSDC@135623|Vibrionales 135623|Vibrionales M COG0739 Membrane proteins related to metalloendopeptidases nlpD - - ko:K06194 - - - - ko00000 1.A.34.1.2 - - LysM,Peptidase_M23 k141_14851_10 223926.28807553 2.68e-132 377.0 COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,1RMHZ@1236|Gammaproteobacteria,1XUP9@135623|Vibrionales 135623|Vibrionales J Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins pcm GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0030091,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 ko:K00573 - - - - ko00000,ko01000 - - - PCMT k141_14851_11 1116375.VEJY3_13190 3.04e-176 492.0 COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,1RN36@1236|Gammaproteobacteria,1XT84@135623|Vibrionales 135623|Vibrionales S Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates surE - 3.1.3.5 ko:K03787 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - SurE k141_14851_12 1116375.VEJY3_13195 3.12e-230 636.0 COG0585@1|root,COG0585@2|Bacteria,1MXHD@1224|Proteobacteria,1RPRF@1236|Gammaproteobacteria,1XTNP@135623|Vibrionales 135623|Vibrionales J Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs truD GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 ko:K06176 - - - - ko00000,ko01000,ko03016 - - - TruD k141_14851_13 1116375.VEJY3_13200 6.08e-107 308.0 COG0245@1|root,COG0245@2|Bacteria,1MVHA@1224|Proteobacteria,1S3RQ@1236|Gammaproteobacteria,1XTA4@135623|Vibrionales 135623|Vibrionales I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) ispF - 4.6.1.12 ko:K01770 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05637 RC00002,RC01440 ko00000,ko00001,ko00002,ko01000 - - - YgbB k141_14851_14 1116375.VEJY3_13205 7.23e-148 418.0 COG1211@1|root,COG1211@2|Bacteria,1MY3B@1224|Proteobacteria,1S21S@1236|Gammaproteobacteria,1XTAS@135623|Vibrionales 135623|Vibrionales I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) ispD GO:0003674,GO:0003824,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050518,GO:0070567,GO:0071704,GO:1901576 2.7.7.60 ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05633 RC00002 ko00000,ko00001,ko00002,ko01000 - - - IspD k141_14851_15 1219076.N646_1654 1.35e-54 171.0 COG2919@1|root,COG2919@2|Bacteria,1N7AA@1224|Proteobacteria,1SD8H@1236|Gammaproteobacteria,1XYBX@135623|Vibrionales 135623|Vibrionales D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic ftsB - - ko:K05589 - - - - ko00000,ko03036 - - - DivIC k141_1761_1 42565.FP66_00185 2.75e-60 189.0 COG0279@1|root,COG0279@2|Bacteria,1NJ8X@1224|Proteobacteria,1RS1Y@1236|Gammaproteobacteria,1XI6S@135619|Oceanospirillales 135619|Oceanospirillales G Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate gmhA - 5.3.1.28 ko:K03271,ko:K12961 ko00540,ko01100,map00540,map01100 M00064 R05645,R09768,R09769 RC00434 ko00000,ko00001,ko00002,ko01000,ko01005,ko03036 - - - SIS_2 k141_1761_2 42565.FP66_00180 5.71e-101 295.0 COG2823@1|root,COG2823@2|Bacteria,1MUZ2@1224|Proteobacteria,1RY2B@1236|Gammaproteobacteria,1XK5U@135619|Oceanospirillales 135619|Oceanospirillales S periplasmic or secreted lipoprotein - - - - - - - - - - - - BON k141_27872_2 665952.HMPREF1015_00750 1.66e-85 263.0 29ECG@1|root,301AF@2|Bacteria,1UY4W@1239|Firmicutes,4HDX6@91061|Bacilli,1ZAV2@1386|Bacillus 91061|Bacilli M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR spoIIGA GO:0003674,GO:0003824,GO:0004175,GO:0004190,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016020,GO:0016021,GO:0016787,GO:0019538,GO:0031224,GO:0031226,GO:0043170,GO:0043621,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0070001,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 - ko:K06383 - - - - ko00000,ko01000,ko01002 - - - Peptidase_U4 k141_7737_1 218284.CCDN010000001_gene24 1.4e-144 441.0 COG1196@1|root,COG1196@2|Bacteria,1TPJV@1239|Firmicutes,4HB89@91061|Bacilli,1ZAWM@1386|Bacillus 91061|Bacilli D Required for chromosome condensation and partitioning smc GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K03529 - - - - ko00000,ko03036 - - - SMC_N,SMC_hinge k141_22060_1 1122927.KB895416_gene3593 1.96e-63 209.0 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4HB97@91061|Bacilli,26T63@186822|Paenibacillaceae 91061|Bacilli C Belongs to the aldehyde dehydrogenase family - - 1.2.1.3 ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_12776_1 1116375.VEJY3_19401 1.36e-74 224.0 COG1733@1|root,COG1733@2|Bacteria,1MZ6N@1224|Proteobacteria,1S6CZ@1236|Gammaproteobacteria,1XXNN@135623|Vibrionales 135623|Vibrionales K transcriptional regulators - - - - - - - - - - - - HxlR k141_12776_2 1116375.VEJY3_19406 4.34e-166 468.0 COG0702@1|root,COG0702@2|Bacteria,1MW44@1224|Proteobacteria,1RPD9@1236|Gammaproteobacteria,1XY9C@135623|Vibrionales 135623|Vibrionales GM NmrA-like family - - 1.6.5.2 ko:K19267 ko00130,ko01110,map00130,map01110 - R02964,R03643,R03816 RC00819 ko00000,ko00001,ko01000 - - - NAD_binding_10,NmrA k141_12776_3 1219076.N646_4391 4.26e-62 192.0 COG1574@1|root,COG1574@2|Bacteria,1P03B@1224|Proteobacteria,1SRVJ@1236|Gammaproteobacteria,1XXH0@135623|Vibrionales 135623|Vibrionales S Cystatin domain - - - - - - - - - - - - Cystatin k141_12776_4 1116375.VEJY3_19456 9.66e-102 296.0 COG3040@1|root,COG3040@2|Bacteria,1RDAI@1224|Proteobacteria,1S3PW@1236|Gammaproteobacteria,1XXE6@135623|Vibrionales 135623|Vibrionales M lipoprotein Blc blc - - ko:K03098 - - - - ko00000,ko04147 - - - Lipocalin_2 k141_12776_5 1116375.VEJY3_19461 9.69e-210 583.0 COG3608@1|root,COG3608@2|Bacteria,1NUX3@1224|Proteobacteria,1RRM4@1236|Gammaproteobacteria,1XSJ9@135623|Vibrionales 135623|Vibrionales S Deacylase - - - ko:K06987 - - - - ko00000 - - - AstE_AspA k141_12776_6 1219076.N646_4387 8.58e-207 581.0 COG1288@1|root,COG1288@2|Bacteria,1MY1J@1224|Proteobacteria,1RS2M@1236|Gammaproteobacteria,1XSXV@135623|Vibrionales 135623|Vibrionales S C4-dicarboxylate anaerobic carrier - - - - - - - - - - - - DcuC k141_5591_1 223926.28805217 2.58e-91 286.0 COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,1RNQ2@1236|Gammaproteobacteria,1XUT0@135623|Vibrionales 135623|Vibrionales GM nucleoside-diphosphate sugar epimerases - - - - - - - - - - - - CoA_binding_3,Polysacc_synt_2 k141_9085_1 29495.EA26_00410 9.23e-80 255.0 COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,1RNJI@1236|Gammaproteobacteria,1XUIR@135623|Vibrionales 135623|Vibrionales L COG0210 Superfamily I DNA and RNA helicases uvrD - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C k141_9085_2 675814.VIC_000474 2.36e-45 147.0 COG5572@1|root,COG5572@2|Bacteria,1PZ3H@1224|Proteobacteria,1SG80@1236|Gammaproteobacteria,1XYG7@135623|Vibrionales 135623|Vibrionales S Integral membrane protein - - - - - - - - - - - - DUF2282 k141_9085_3 1116375.VEJY3_15190 7.28e-173 486.0 COG3220@1|root,COG3220@2|Bacteria,1MURE@1224|Proteobacteria,1RQ9H@1236|Gammaproteobacteria,1XTSI@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria - - - ko:K09930 - - - - ko00000 - - - DUF692 k141_9085_5 1116375.VEJY3_15205 3.57e-55 172.0 2AWB4@1|root,31N6T@2|Bacteria,1QJY2@1224|Proteobacteria,1TI09@1236|Gammaproteobacteria,1XY2K@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_9085_6 1116375.VEJY3_15210 1.8e-261 720.0 COG0477@1|root,COG2814@2|Bacteria,1MW19@1224|Proteobacteria,1RRYY@1236|Gammaproteobacteria,1XSVS@135623|Vibrionales 135623|Vibrionales EGP COG0477 Permeases of the major facilitator superfamily mdtL - - ko:K07552 - - - - ko00000,ko02000 2.A.1.2 - - MFS_1 k141_9085_7 223926.28808046 1.47e-118 345.0 COG0583@1|root,COG0583@2|Bacteria,1N8FH@1224|Proteobacteria,1RRIV@1236|Gammaproteobacteria,1Y31S@135623|Vibrionales 135623|Vibrionales K Bacterial regulatory helix-turn-helix protein, lysR family - - - - - - - - - - - - HTH_1,LysR_substrate k141_35253_1 218284.CCDN010000009_gene4275 1.4e-39 142.0 COG4856@1|root,COG4856@2|Bacteria,1TSIV@1239|Firmicutes,4HD8Y@91061|Bacilli,1ZB2T@1386|Bacillus 91061|Bacilli S protein conserved in bacteria ybbR GO:0008150,GO:0031279,GO:0031281,GO:0043085,GO:0044093,GO:0045761,GO:0045762,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009 - - - - - - - - - - YbbR k141_6691_1 218284.CCDN010000002_gene2396 2.42e-109 328.0 COG0697@1|root,COG0697@2|Bacteria,1TP7K@1239|Firmicutes,4HAH1@91061|Bacilli,1ZBEF@1386|Bacillus 91061|Bacilli EG Spore germination protein - - - ko:K06295 - - - - ko00000 - - - GerA k141_14852_2 1042377.AFPJ01000052_gene1536 1.63e-80 245.0 COG4464@1|root,COG4464@2|Bacteria,1R5E2@1224|Proteobacteria,1S34B@1236|Gammaproteobacteria,46710@72275|Alteromonadaceae 1236|Gammaproteobacteria GM Capsular polysaccharide biosynthesis protein ywqE - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - - k141_13989_1 218284.CCDN010000002_gene2153 4.17e-120 347.0 2CABP@1|root,2Z7KZ@2|Bacteria,1U7V1@1239|Firmicutes,4HCY6@91061|Bacilli,1ZGH3@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_14853_1 218284.CCDN010000005_gene3458 5.65e-107 309.0 COG2032@1|root,COG2032@2|Bacteria,1V652@1239|Firmicutes,4HH67@91061|Bacilli,1ZE46@1386|Bacillus 91061|Bacilli P Destroys radicals which are normally produced within the cells and which are toxic to biological systems sodC GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0005488,GO:0005507,GO:0005515,GO:0005575,GO:0005576,GO:0005615,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008270,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044237,GO:0044421,GO:0046872,GO:0046914,GO:0046983,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1 ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 - - - ko00000,ko00001,ko01000 - - - Sod_Cu k141_16131_1 501479.ACNW01000047_gene425 1.06e-109 326.0 COG0600@1|root,COG0600@2|Bacteria,1MWDJ@1224|Proteobacteria,2TRDG@28211|Alphaproteobacteria 28211|Alphaproteobacteria P ABC-type nitrate sulfonate bicarbonate transport system permease component tauC - - ko:K15552 ko00920,ko02010,map00920,map02010 M00435 - - ko00000,ko00001,ko00002,ko02000 3.A.1.17.1,3.A.1.17.4 - - BPD_transp_1 k141_27873_1 1453501.JELR01000002_gene1212 4.34e-54 174.0 COG2433@1|root,COG2433@2|Bacteria,1N0ZS@1224|Proteobacteria,1SBFE@1236|Gammaproteobacteria,46CTE@72275|Alteromonadaceae 1236|Gammaproteobacteria S Pfam Transposase IS66 - - - - - - - - - - - - - k141_29160_1 1177154.Y5S_01706 4.01e-137 438.0 COG1361@1|root,COG1361@2|Bacteria,1QVSF@1224|Proteobacteria 1224|Proteobacteria M domain protein - - - - - - - - - - - - CARDB,DUF11,OmpA_membrane k141_20816_2 9940.ENSOARP00000010474 1.6e-21 94.7 COG0044@1|root,KOG2584@2759|Eukaryota,38E62@33154|Opisthokonta,3B9YN@33208|Metazoa,3CV8R@33213|Bilateria,4862C@7711|Chordata,49574@7742|Vertebrata,3J4Q6@40674|Mammalia,4IWAN@91561|Cetartiodactyla 33208|Metazoa F Dihydropyrimidinase-related protein 2 isoform DPYSL2 GO:0001558,GO:0001975,GO:0003008,GO:0003674,GO:0003824,GO:0004157,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0006810,GO:0006897,GO:0006996,GO:0007010,GO:0007154,GO:0007165,GO:0007264,GO:0007265,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0007610,GO:0007611,GO:0007613,GO:0008150,GO:0008152,GO:0008361,GO:0008593,GO:0009058,GO:0009112,GO:0009410,GO:0009636,GO:0009966,GO:0009967,GO:0009987,GO:0010033,GO:0010243,GO:0010646,GO:0010647,GO:0010769,GO:0010975,GO:0014048,GO:0014049,GO:0014070,GO:0014075,GO:0016020,GO:0016043,GO:0016192,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019856,GO:0019899,GO:0019900,GO:0019901,GO:0021510,GO:0021537,GO:0021772,GO:0021988,GO:0022008,GO:0022603,GO:0022604,GO:0023051,GO:0023052,GO:0023056,GO:0030154,GO:0030424,GO:0030425,GO:0030426,GO:0030427,GO:0030516,GO:0030900,GO:0031344,GO:0032501,GO:0032502,GO:0032535,GO:0032879,GO:0032890,GO:0032892,GO:0032991,GO:0033267,GO:0034641,GO:0035556,GO:0036477,GO:0040008,GO:0042220,GO:0042221,GO:0042493,GO:0042802,GO:0042995,GO:0043005,GO:0043025,GO:0043209,GO:0043269,GO:0043270,GO:0043279,GO:0044070,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044297,GO:0044424,GO:0044444,GO:0044463,GO:0044464,GO:0045595,GO:0045664,GO:0045747,GO:0046112,GO:0046483,GO:0046907,GO:0048489,GO:0048513,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0048638,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0050767,GO:0050770,GO:0050789,GO:0050793,GO:0050794,GO:0050877,GO:0050890,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051128,GO:0051179,GO:0051234,GO:0051239,GO:0051640,GO:0051641,GO:0051642,GO:0051648,GO:0051649,GO:0051650,GO:0051656,GO:0051716,GO:0051952,GO:0051954,GO:0051955,GO:0051957,GO:0051960,GO:0055086,GO:0060284,GO:0060322,GO:0060359,GO:0061387,GO:0061842,GO:0065007,GO:0065008,GO:0071704,GO:0071840,GO:0071944,GO:0072347,GO:0072527,GO:0072528,GO:0090066,GO:0097366,GO:0097447,GO:0097458,GO:0097479,GO:0097480,GO:0098657,GO:0099003,GO:0120025,GO:0120035,GO:0120038,GO:0150034,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901698,GO:1901700,GO:1903530,GO:1903532,GO:1903793,GO:2000026 3.5.2.2 ko:K01464,ko:K07528 ko00240,ko00410,ko00770,ko00983,ko01100,ko04360,map00240,map00410,map00770,map00983,map01100,map04360 M00046 R02269,R03055,R08227 RC00632,RC00680 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Amidohydro_1 k141_27128_1 177437.HRM2_15550 6.06e-46 166.0 COG3547@1|root,COG3547@2|Bacteria,1MUKH@1224|Proteobacteria,42NNJ@68525|delta/epsilon subdivisions,2WKP9@28221|Deltaproteobacteria,2MKV7@213118|Desulfobacterales 28221|Deltaproteobacteria L PFAM transposase IS116 IS110 IS902 family - - - - - - - - - - - - DEDD_Tnp_IS110,DUF2924,Transposase_20 k141_9086_3 1279017.AQYJ01000024_gene912 4.12e-54 189.0 COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RNWM@1236|Gammaproteobacteria,465X0@72275|Alteromonadaceae 1236|Gammaproteobacteria S exporters of the RND superfamily - - - ko:K07003 - - - - ko00000 - - - MMPL k141_12777_1 883126.HMPREF9710_04714 7.51e-76 233.0 COG1741@1|root,COG1741@2|Bacteria,1MVSW@1224|Proteobacteria,2VHPA@28216|Betaproteobacteria,4734U@75682|Oxalobacteraceae 28216|Betaproteobacteria S Belongs to the pirin family yhhW_2 - - ko:K06911 - - - - ko00000 - - - Pirin k141_5592_1 218284.CCDN010000001_gene1490 8.93e-95 294.0 COG0187@1|root,COG0187@2|Bacteria,1TQCF@1239|Firmicutes,4H9UC@91061|Bacilli,1ZBMM@1386|Bacillus 91061|Bacilli L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parE GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 - ko:K02622 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim k141_30254_1 218284.CCDN010000001_gene65 4.36e-84 250.0 COG0597@1|root,COG0597@2|Bacteria,1VA9R@1239|Firmicutes,4HIR4@91061|Bacilli,1ZGBF@1386|Bacillus 91061|Bacilli MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins lspA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.4.23.36 ko:K03101 ko03060,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_A8 k141_10370_1 1238184.CM001792_gene1928 4.08e-25 101.0 COG0142@1|root,COG0142@2|Bacteria,1TPQY@1239|Firmicutes,4HA8E@91061|Bacilli,23JKA@182709|Oceanobacillus 91061|Bacilli H Polyprenyl synthetase ispA GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0071704,GO:1901576 2.5.1.1,2.5.1.10,2.5.1.29 ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00366 R01658,R02003,R02061 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 - - - polyprenyl_synt k141_25824_1 866895.HBHAL_2075 2.48e-30 122.0 2EIND@1|root,33CDR@2|Bacteria,1VKQB@1239|Firmicutes,4HR5V@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - k141_11545_2 1279017.AQYJ01000021_gene2905 1.07e-197 558.0 COG0477@1|root,COG2814@2|Bacteria,1RAYJ@1224|Proteobacteria,1S7XJ@1236|Gammaproteobacteria,46AYE@72275|Alteromonadaceae 1236|Gammaproteobacteria EGP Transmembrane secretion effector - - - - - - - - - - - - MFS_1,MFS_3 k141_11545_3 1279017.AQYJ01000021_gene2904 0.0 916.0 COG1305@1|root,COG1305@2|Bacteria,1MWCE@1224|Proteobacteria,1RPH9@1236|Gammaproteobacteria,464NQ@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG1305 Transglutaminase-like enzymes tgpA - 2.3.2.13 ko:K22452 - - - - ko00000,ko01000 - - - DUF3488,DUF4129,Transglut_core k141_11545_4 1453501.JELR01000001_gene1844 6.09e-143 414.0 COG1721@1|root,COG1721@2|Bacteria,1R3QD@1224|Proteobacteria,1S5F7@1236|Gammaproteobacteria,466X1@72275|Alteromonadaceae 1236|Gammaproteobacteria S conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - - - - - - - - - - DUF58 k141_11545_6 1042377.AFPJ01000037_gene2991 4.1e-243 672.0 COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,1RMCV@1236|Gammaproteobacteria,464GC@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide metZ - 4.4.1.11 ko:K01761,ko:K10764 ko00270,ko00450,ko00920,ko01100,map00270,map00450,map00920,map01100 - R00654,R01288,R04770 RC00020,RC00196,RC00348,RC01209,RC01210,RC02848 ko00000,ko00001,ko01000 - - - Cys_Met_Meta_PP k141_11545_8 1453501.JELR01000001_gene1840 1.49e-90 268.0 COG1286@1|root,COG1286@2|Bacteria,1NF4G@1224|Proteobacteria,1RQ58@1236|Gammaproteobacteria,467N8@72275|Alteromonadaceae 1236|Gammaproteobacteria S membrane protein, required for colicin V production cvpA GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009403,GO:0009404,GO:0009987,GO:0016020,GO:0019748,GO:0044237,GO:0044249,GO:0044464,GO:0044550,GO:0071944 - ko:K03558 - - - - ko00000 - - - Colicin_V k141_24736_1 1174504.AJTN02000180_gene1981 3.07e-60 202.0 COG0075@1|root,COG3916@1|root,COG0075@2|Bacteria,COG3916@2|Bacteria,1TR3I@1239|Firmicutes,4HA6W@91061|Bacilli,1ZAT2@1386|Bacillus 91061|Bacilli E Aminotransferase class-V - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10,Acetyltransf_5,Acetyltransf_9,Aminotran_5 k141_3222_1 218284.CCDN010000001_gene1789 8.79e-80 239.0 2EUDS@1|root,33MW4@2|Bacteria,1VHIA@1239|Firmicutes,4HSFG@91061|Bacilli,1ZEP8@1386|Bacillus 91061|Bacilli S Sporulation inhibitor of replication protein sirA yneE - - - - - - - - - - - SirA k141_32925_2 1453501.JELR01000001_gene2991 2.34e-133 385.0 COG0584@1|root,COG0584@2|Bacteria,1MU8H@1224|Proteobacteria,1RQWX@1236|Gammaproteobacteria,466VV@72275|Alteromonadaceae 1236|Gammaproteobacteria C glycerophosphoryl diester phosphodiesterase ugpQ - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - GDPD k141_32925_3 1279017.AQYJ01000024_gene937 4.38e-89 265.0 COG1853@1|root,COG1853@2|Bacteria,1RGYM@1224|Proteobacteria,1S97V@1236|Gammaproteobacteria,468E0@72275|Alteromonadaceae 1236|Gammaproteobacteria K Flavin reductase like domain - - - ko:K09024 ko00240,ko01100,map00240,map01100 - R09936 RC02732 ko00000,ko00001,ko01000 - - - Flavin_Reduct k141_32925_4 1042377.AFPJ01000034_gene2418 3.69e-270 754.0 COG0446@1|root,COG1773@1|root,COG0446@2|Bacteria,COG1773@2|Bacteria,1NR3M@1224|Proteobacteria,1RQ07@1236|Gammaproteobacteria,46561@72275|Alteromonadaceae 1236|Gammaproteobacteria C NAD(FAD)-dependent dehydrogenases rubB - 1.18.1.1 ko:K05297 ko00071,map00071 - R02000 - ko00000,ko00001,ko01000 - - - Pyr_redox_2,Rubredoxin k141_32925_5 1279017.AQYJ01000024_gene939 1.64e-131 375.0 COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,1RSY6@1236|Gammaproteobacteria,466D6@72275|Alteromonadaceae 1236|Gammaproteobacteria P Reversible hydration of carbon dioxide can GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008270,GO:0015976,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914 4.2.1.1 ko:K01673 ko00910,map00910 - R00132,R10092 RC02807 ko00000,ko00001,ko01000 - - iSBO_1134.SBO_0115,iSbBS512_1146.SbBS512_E0119 Pro_CA k141_22426_1 218284.CCDN010000002_gene2091 1.11e-245 682.0 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli,1ZAY9@1386|Bacillus 91061|Bacilli C Belongs to the aldehyde dehydrogenase family - - 1.2.1.3,1.2.1.8 ko:K00128,ko:K00130 ko00010,ko00053,ko00071,ko00260,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00260,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135,M00555 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02565,R02566,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_11786_1 1116375.VEJY3_06255 6.59e-156 444.0 COG0027@1|root,COG0027@2|Bacteria,1N3KA@1224|Proteobacteria,1RNTW@1236|Gammaproteobacteria,1XUDQ@135623|Vibrionales 135623|Vibrionales F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate purT GO:0003674,GO:0003824,GO:0004644,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.2.2 ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04325,R04326 RC00026,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp,Epimerase k141_11786_2 1116375.VEJY3_06260 2.21e-197 548.0 COG0295@1|root,COG0295@2|Bacteria,1MY2R@1224|Proteobacteria,1RMRX@1236|Gammaproteobacteria,1XV0Z@135623|Vibrionales 135623|Vibrionales F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis cdd GO:0003674,GO:0003824,GO:0004126,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006216,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008655,GO:0009056,GO:0009058,GO:0009116,GO:0009119,GO:0009164,GO:0009972,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0043094,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046087,GO:0046131,GO:0046133,GO:0046135,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.5.4.5 ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R01878,R02485,R08221 RC00074,RC00514 ko00000,ko00001,ko01000 - - - dCMP_cyt_deam_1,dCMP_cyt_deam_2 k141_11786_3 1116375.VEJY3_06265 2.27e-48 159.0 COG1346@1|root,COG1346@2|Bacteria,1MV81@1224|Proteobacteria,1RS5C@1236|Gammaproteobacteria,1XT9T@135623|Vibrionales 135623|Vibrionales M effector of murein hydrolase yohK - - - - - - - - - - - LrgB k141_19998_1 1116375.VEJY3_11930 0.0 1300.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RPM5@1236|Gammaproteobacteria,1XTG6@135623|Vibrionales 135623|Vibrionales I COG1960 Acyl-CoA dehydrogenases fadE - - ko:K06445 ko00071,ko01100,ko01212,map00071,map01100,map01212 M00087 R01175,R01279,R03777,R03857,R03990,R04751,R04754 RC00052,RC00076 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_N,DUF1974 k141_19998_2 223926.28807281 1.22e-131 374.0 COG0279@1|root,COG0279@2|Bacteria,1NVIE@1224|Proteobacteria,1RP6M@1236|Gammaproteobacteria,1XSJH@135623|Vibrionales 135623|Vibrionales G Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate gmhA GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008968,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016853,GO:0016866,GO:0016868,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0046401,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 5.3.1.28 ko:K03271 ko00540,ko01100,map00540,map01100 M00064 R05645,R09768,R09769 RC00434 ko00000,ko00001,ko00002,ko01000,ko01005 - - - SIS_2 k141_19998_3 1116375.VEJY3_11920 2.26e-208 575.0 COG0121@1|root,COG0121@2|Bacteria,1MU1J@1224|Proteobacteria,1RNEK@1236|Gammaproteobacteria,1XTCN@135623|Vibrionales 135623|Vibrionales S glutamine amidotransferase yafJ - - - - - - - - - - - GATase_4 k141_19998_4 1116375.VEJY3_11915 1.88e-140 398.0 COG0299@1|root,COG0299@2|Bacteria,1MWN1@1224|Proteobacteria,1RMHS@1236|Gammaproteobacteria,1XSWT@135623|Vibrionales 135623|Vibrionales F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate purN - 2.1.2.2 ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04325,R04326 RC00026,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 - - - Formyl_trans_N k141_19998_5 223926.28807278 7.36e-249 683.0 COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,1RNZZ@1236|Gammaproteobacteria,1XSF7@135623|Vibrionales 135623|Vibrionales F Phosphoribosylformylglycinamidine cyclo-ligase purM GO:0003674,GO:0003824,GO:0004641,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.1 ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04208 RC01100 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C k141_19998_6 1280001.BAOA01000081_gene3014 1.76e-142 402.0 COG0035@1|root,COG0035@2|Bacteria,1MV4N@1224|Proteobacteria,1RPBG@1236|Gammaproteobacteria,1XTNV@135623|Vibrionales 135623|Vibrionales F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate upp GO:0003674,GO:0003824,GO:0004845,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016763,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 ko:K00761 ko00240,ko01100,map00240,map01100 - R00966 RC00063 ko00000,ko00001,ko01000 - - - UPRTase k141_19998_7 223926.28807276 9.67e-274 752.0 COG2233@1|root,COG2233@2|Bacteria,1MUN9@1224|Proteobacteria,1RRK5@1236|Gammaproteobacteria,1XT83@135623|Vibrionales 135623|Vibrionales F COG2233 Xanthine uracil permeases uraA - - ko:K02824 - - - - ko00000,ko02000 2.A.40.1.1,2.A.40.1.2 - - Xan_ur_permease k141_23761_1 1294265.JCM21738_1730 6.01e-123 390.0 COG1404@1|root,COG1520@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria,1TPUY@1239|Firmicutes,4HBDE@91061|Bacilli,1ZDEQ@1386|Bacillus 91061|Bacilli O COG1404 Subtilisin-like serine proteases - - - - - - - - - - - - CarbopepD_reg_2,CarboxypepD_reg,Peptidase_S8 k141_32926_1 1307436.PBF_04893 2.09e-07 52.4 2BS55@1|root,32M63@2|Bacteria,1U272@1239|Firmicutes,4IBQY@91061|Bacilli,1ZHCJ@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_3223_1 666686.B1NLA3E_04655 4.47e-81 245.0 COG0664@1|root,COG0664@2|Bacteria,1V1AS@1239|Firmicutes,4HF4V@91061|Bacilli,1ZD74@1386|Bacillus 91061|Bacilli K COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases fnr_1 - - - - - - - - - - - HTH_Crp_2,cNMP_binding k141_1056_2 218284.CCDN010000006_gene3632 6.04e-37 130.0 COG2755@1|root,COG2755@2|Bacteria,1UZKM@1239|Firmicutes,4HVJ0@91061|Bacilli,1ZEST@1386|Bacillus 91061|Bacilli E GDSL-like Lipase/Acylhydrolase - - - - - - - - - - - - Lipase_GDSL_2 k141_19999_1 1453501.JELR01000001_gene2603 3.74e-44 145.0 COG2391@1|root,COG2391@2|Bacteria,1MZC0@1224|Proteobacteria,1S8UB@1236|Gammaproteobacteria,467VW@72275|Alteromonadaceae 1236|Gammaproteobacteria S Transporter component - - - ko:K07112 - - - - ko00000 - - - Sulf_transp k141_19999_2 1042377.AFPJ01000017_gene19 3.74e-60 187.0 COG2391@1|root,COG2391@2|Bacteria,1MZ3A@1224|Proteobacteria,1S95T@1236|Gammaproteobacteria,467ZA@72275|Alteromonadaceae 1236|Gammaproteobacteria S Transporter component - - - ko:K07112 - - - - ko00000 - - - Sulf_transp k141_10473_1 1279017.AQYJ01000023_gene3271 6.53e-14 66.2 COG5591@1|root,COG5591@2|Bacteria,1N7TH@1224|Proteobacteria,1SF7U@1236|Gammaproteobacteria,46BWG@72275|Alteromonadaceae 1236|Gammaproteobacteria S Peptidase propeptide and YPEB domain - - - - - - - - - - - - PepSY_2 k141_10473_3 1279017.AQYJ01000028_gene2453 2.96e-31 118.0 COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,1RQJD@1236|Gammaproteobacteria,466WW@72275|Alteromonadaceae 1236|Gammaproteobacteria K Bacterial regulatory helix-turn-helix protein, lysR family - - - ko:K21703 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate k141_15104_1 218284.CCDN010000006_gene3729 1.53e-78 258.0 COG0737@1|root,COG2247@1|root,COG0737@2|Bacteria,COG2247@2|Bacteria,1TPV2@1239|Firmicutes,4H9VJ@91061|Bacilli,1ZS4T@1386|Bacillus 91061|Bacilli F COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases cpdB - 3.1.3.5,3.1.3.6,3.1.4.16,3.6.1.45 ko:K01081,ko:K07004,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01562,R01569,R01664,R01877,R01968,R02088,R02102,R02148,R02323,R02370,R02719,R03346,R03537,R03538,R03929,R05135 RC00017,RC00078,RC00296 ko00000,ko00001,ko01000 - - - 5_nucleotid_C,CHB_HEX_C_1,Gram_pos_anchor,LTD,Metallophos,SLH k141_34221_1 225849.swp_1626 1.42e-63 209.0 COG0446@1|root,COG0446@2|Bacteria,1Q0P8@1224|Proteobacteria,1T1NQ@1236|Gammaproteobacteria,2QAD4@267890|Shewanellaceae 1236|Gammaproteobacteria S Tryptophan halogenase - - 1.14.19.9 ko:K14266 ko00404,ko01130,map00404,map01130 M00789,M00790 R09570 RC00949 ko00000,ko00001,ko00002,ko01000 - - - Trp_halogenase k141_7021_2 1382358.JHVN01000024_gene1717 2.22e-93 295.0 COG4722@1|root,COG4722@2|Bacteria,1TRIA@1239|Firmicutes,4HB9H@91061|Bacilli 91061|Bacilli S Phage tail protein - - - - - - - - - - - - Sipho_tail k141_24738_1 218284.CCDN010000007_gene3999 3.59e-189 535.0 COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,4HAMZ@91061|Bacilli,1ZB13@1386|Bacillus 91061|Bacilli C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit atpA - 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - iSB619.SA_RS10975 ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N k141_11788_1 218284.CCDN010000002_gene2183 2.04e-113 330.0 COG1503@1|root,COG1503@2|Bacteria,1TT2U@1239|Firmicutes,4HC2I@91061|Bacilli,1ZECE@1386|Bacillus 91061|Bacilli J translation release factor activity - - - - - - - - - - - - - k141_3224_1 1453501.JELR01000001_gene2888 2.43e-84 266.0 COG4805@1|root,COG4805@2|Bacteria,1R5EP@1224|Proteobacteria,1RRS6@1236|Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - DUF885 k141_32927_1 1453501.JELR01000002_gene133 1.53e-26 99.0 2E7BZ@1|root,331V9@2|Bacteria,1N8MZ@1224|Proteobacteria 1224|Proteobacteria S Domain of Unknown Function (DUF1540) - - - - - - - - - - - - DUF1540 k141_32927_2 498211.CJA_1494 3.3e-49 169.0 COG0738@1|root,COG0738@2|Bacteria,1MXDC@1224|Proteobacteria,1RQX9@1236|Gammaproteobacteria,1FHW2@10|Cellvibrio 1236|Gammaproteobacteria G Major Facilitator Superfamily gluP - - ko:K02429 - - - - ko00000,ko02000 2.A.1.7 - - MFS_1 k141_10474_1 999411.HMPREF1092_01196 1.73e-09 62.0 COG0116@1|root,COG0116@2|Bacteria,1TP0X@1239|Firmicutes,248MA@186801|Clostridia,36E5D@31979|Clostridiaceae 186801|Clostridia L Belongs to the methyltransferase superfamily ypsC - - ko:K07444 - - - - ko00000,ko01000 - - - THUMP,UPF0020 k141_5767_1 1116375.VEJY3_02955 4.35e-131 374.0 COG2197@1|root,COG2197@2|Bacteria,1R9GN@1224|Proteobacteria,1S4YI@1236|Gammaproteobacteria,1XUAU@135623|Vibrionales 1236|Gammaproteobacteria K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - - - - - - - - - - GerE,Response_reg k141_5767_2 1238450.VIBNISOn1_370011 5.77e-94 288.0 COG1840@1|root,COG1840@2|Bacteria,1MWWI@1224|Proteobacteria,1RRWU@1236|Gammaproteobacteria,1XWMU@135623|Vibrionales 135623|Vibrionales P Bacterial extracellular solute-binding protein - - - ko:K08478 ko02020,map02020 - - - ko00000,ko00001 - - - SBP_bac_6 k141_16337_1 697284.ERIC2_c03570 1.9e-125 367.0 COG1619@1|root,COG1619@2|Bacteria,1TZSN@1239|Firmicutes,4HCD4@91061|Bacilli,26SRU@186822|Paenibacillaceae 91061|Bacilli V Peptidase S66 - - - - - - - - - - - - Peptidase_S66 k141_36400_1 866895.HBHAL_3192 1.48e-21 87.4 2DQ26@1|root,334FG@2|Bacteria,1VGDU@1239|Firmicutes,4HQWD@91061|Bacilli,3NFIJ@45667|Halobacillus 91061|Bacilli S Cold-inducible protein YdjO - - - - - - - - - - - - YdjO k141_7022_2 1294265.JCM21738_79 8.48e-123 354.0 COG1408@1|root,COG1408@2|Bacteria,1V494@1239|Firmicutes,4HH1B@91061|Bacilli,1ZBFW@1386|Bacillus 91061|Bacilli S Calcineurin-like phosphoesterase superfamily domain ypbG - - ko:K07098 - - - - ko00000 - - - Metallophos,Metallophos_2 k141_10475_1 545264.KB898745_gene1259 1.11e-70 223.0 COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,1RNB6@1236|Gammaproteobacteria,1WWMZ@135613|Chromatiales 135613|Chromatiales E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate asd - 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC k141_11789_1 1131730.BAVI_03879 2.67e-174 499.0 COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HANF@91061|Bacilli,1ZS27@1386|Bacillus 91061|Bacilli T Histidine kinase - - - - - - - - - - - - HAMP,HATPase_c,HisKA k141_31545_1 265729.GS18_0210795 1.18e-83 250.0 COG0225@1|root,COG0225@2|Bacteria,1V1MJ@1239|Firmicutes,4HG4U@91061|Bacilli,1ZRBW@1386|Bacillus 91061|Bacilli O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine msrA - 1.8.4.11 ko:K07304 - - - - ko00000,ko01000 - - - PMSR k141_12951_1 1279017.AQYJ01000025_gene766 2.72e-123 354.0 COG0529@1|root,COG0529@2|Bacteria,1MX0D@1224|Proteobacteria,1RNWT@1236|Gammaproteobacteria,465TQ@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the synthesis of activated sulfate cysC - 2.7.1.25,2.7.7.4 ko:K00860,ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176,M00596 R00509,R00529,R04928,R04929 RC00002,RC00078,RC02809,RC02889 ko00000,ko00001,ko00002,ko01000 - - - APS_kinase,ATP-sulfurylase,PUA_2 k141_24740_1 1347086.CCBA010000022_gene2971 6.29e-73 235.0 COG4468@1|root,COG4468@2|Bacteria,1TPBN@1239|Firmicutes,4HAYJ@91061|Bacilli,1ZAVT@1386|Bacillus 91061|Bacilli G UDP-glucose--hexose-1-phosphate uridylyltransferase galT - 2.7.7.12 ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 M00362,M00554,M00632 R00955 RC00002 ko00000,ko00001,ko00002,ko01000 - - - GalP_UDP_tr_C,GalP_UDP_transf k141_37614_2 218284.CCDN010000002_gene2004 6.12e-111 327.0 COG0002@1|root,COG0002@2|Bacteria,1TPVI@1239|Firmicutes,4H9YD@91061|Bacilli,1ZBHP@1386|Bacillus 91061|Bacilli E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde argC GO:0003674,GO:0003824,GO:0003942,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.38 ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R03443 RC00684 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU11190 Semialdhyde_dh,Semialdhyde_dhC k141_9414_1 218284.CCDN010000002_gene2869 7.18e-79 243.0 COG1173@1|root,COG1173@2|Bacteria,1V21B@1239|Firmicutes,4HJ5Y@91061|Bacilli,1ZFPK@1386|Bacillus 91061|Bacilli EP ABC transporter (permease) - - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 k141_9414_2 218284.CCDN010000002_gene2868 5.3e-10 58.9 COG0601@1|root,COG0601@2|Bacteria,1UYTT@1239|Firmicutes,4IEZM@91061|Bacilli,1ZJ9K@1386|Bacillus 91061|Bacilli EP Binding-protein-dependent transport system inner membrane component - - - - - - - - - - - - BPD_transp_1 k141_30394_1 218284.CCDN010000005_gene3471 7.24e-162 460.0 COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,4HA2Y@91061|Bacilli,1ZAV3@1386|Bacillus 91061|Bacilli E Catalyzes the interconversion of ornithine to glutamate semialdehyde rocD GO:0003674,GO:0003824,GO:0004587,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009064,GO:0009987,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901605 2.6.1.13 ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 - R00667 RC00006,RC00062 ko00000,ko00001,ko01000,ko01007 - - iYO844.BSU40340 Aminotran_3 k141_9415_1 218284.CCDN010000001_gene1218 7.31e-53 174.0 COG0454@1|root,COG0456@2|Bacteria,1V4AF@1239|Firmicutes,4HD36@91061|Bacilli,1ZCVH@1386|Bacillus 91061|Bacilli K Acetyltransferase (GNAT) family yodP - 2.3.1.264 ko:K21935 - - R11701 - ko00000,ko01000 - - - Acetyltransf_1,Acetyltransf_9 k141_37617_1 1294265.JCM21738_4202 5.68e-34 125.0 2DH6Y@1|root,2ZYKQ@2|Bacteria,1V3RR@1239|Firmicutes,4HHKE@91061|Bacilli,1ZBHI@1386|Bacillus 91061|Bacilli S Spore germination B3/ GerAC like, C-terminal - - - ko:K06308 - - - - ko00000 - - - Spore_GerAC k141_37617_2 1294265.JCM21738_4201 3.68e-69 215.0 COG0772@1|root,COG0772@2|Bacteria,1TPGH@1239|Firmicutes,4HAV4@91061|Bacilli,1ZBSB@1386|Bacillus 91061|Bacilli D Belongs to the SEDS family - - - ko:K05837 - - - - ko00000,ko03036 - - - FTSW_RODA_SPOVE k141_15106_1 765911.Thivi_2998 3.91e-12 72.4 COG0612@1|root,COG0612@2|Bacteria,1MU6R@1224|Proteobacteria,1RN3E@1236|Gammaproteobacteria,1WXE8@135613|Chromatiales 135613|Chromatiales S PFAM Peptidase M16 - - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C k141_12955_1 1033802.SSPSH_000964 3.98e-60 199.0 COG2271@1|root,COG2271@2|Bacteria,1QXP5@1224|Proteobacteria,1T4EF@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 k141_5768_2 935836.JAEL01000013_gene4481 4.09e-61 198.0 COG0156@1|root,COG0156@2|Bacteria,1TPUX@1239|Firmicutes,4HAH3@91061|Bacilli,1ZAUZ@1386|Bacillus 91061|Bacilli H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide kbl GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29 ko:K00639 ko00260,map00260 - R00371 RC00004,RC00394 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 k141_16338_1 1169144.KB910931_gene982 3.41e-09 59.7 COG0476@1|root,COG0476@2|Bacteria,1UZJC@1239|Firmicutes,4HB2K@91061|Bacilli,1ZBN2@1386|Bacillus 91061|Bacilli H bacteriocin maturation protein - - - - - - - - - - - - - k141_16338_2 218284.CCDN010000001_gene385 2.81e-58 197.0 COG1944@1|root,COG1944@2|Bacteria,1UYIC@1239|Firmicutes,4HDGN@91061|Bacilli,1ZDA2@1386|Bacillus 91061|Bacilli S YcaO cyclodehydratase, ATP-ad Mg2+-binding - - - ko:K09136 - - - - ko00000,ko03009 - - - YcaO k141_20022_1 223926.28805602 1.62e-115 343.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,1RMT8@1236|Gammaproteobacteria,1XT7Z@135623|Vibrionales 135623|Vibrionales F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth guaB - 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 - - - CBS,IMPDH k141_20022_2 223926.28805601 1.28e-211 594.0 COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,1RNAZ@1236|Gammaproteobacteria,1XSYD@135623|Vibrionales 135623|Vibrionales L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseA GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494 3.1.11.6 ko:K03601 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_L,tRNA_anti_2 k141_35520_1 218284.CCDN010000002_gene2758 1.2e-55 192.0 COG0577@1|root,COG0577@2|Bacteria,1TPHU@1239|Firmicutes,4HA2C@91061|Bacilli,1ZG12@1386|Bacillus 91061|Bacilli V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX k141_35520_2 218284.CCDN010000002_gene2757 1.68e-46 155.0 COG1136@1|root,COG1136@2|Bacteria,1TQC9@1239|Firmicutes,4HB8D@91061|Bacilli,1ZREB@1386|Bacillus 91061|Bacilli V ATPases associated with a variety of cellular activities macB - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_3242_1 218284.CCDN010000001_gene188 3.86e-162 456.0 COG1028@1|root,COG1028@2|Bacteria,1TPDB@1239|Firmicutes,4HAKR@91061|Bacilli,1ZDEP@1386|Bacillus 91061|Bacilli IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) fadH - 1.3.1.34 ko:K00219 - - - - ko00000,ko01000 - - - adh_short_C2 k141_11824_1 1453501.JELR01000002_gene131 1.74e-70 218.0 COG2197@1|root,COG2197@2|Bacteria,1P4TD@1224|Proteobacteria,1RU35@1236|Gammaproteobacteria,466GT@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain tcsR - - - - - - - - - - - GerE,Response_reg k141_29429_1 42565.FP66_10190 4.84e-190 553.0 COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,1RMTF@1236|Gammaproteobacteria,1XHN6@135619|Oceanospirillales 135619|Oceanospirillales J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS - 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1,zf-FPG_IleRS k141_17430_1 218284.CCDN010000002_gene1985 5.85e-166 464.0 COG0152@1|root,COG0152@2|Bacteria,1TP11@1239|Firmicutes,4H9U8@91061|Bacilli,1ZAWJ@1386|Bacillus 91061|Bacilli F Belongs to the SAICAR synthetase family purC - 6.3.2.6 ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04591 RC00064,RC00162 ko00000,ko00001,ko00002,ko01000 - - - SAICAR_synt k141_10485_2 218284.CCDN010000002_gene2144 2.18e-72 231.0 COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,4H9W6@91061|Bacilli,1ZD0J@1386|Bacillus 91061|Bacilli G Belongs to the FGGY kinase family gntK - 2.7.1.12 ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 - R01737 RC00002,RC00017 ko00000,ko00001,ko01000 - - - FGGY_C,FGGY_N k141_5787_1 218284.CCDN010000001_gene783 8.12e-149 431.0 COG1283@1|root,COG1283@2|Bacteria,1TP4K@1239|Firmicutes,4HAZ0@91061|Bacilli,1ZBHZ@1386|Bacillus 91061|Bacilli P COG1283 Na phosphate symporter yjbB - - ko:K03324 - - - - ko00000,ko02000 2.A.58.2 - - Na_Pi_cotrans,PhoU k141_12969_1 1294265.JCM21738_2780 4.58e-83 246.0 29RHG@1|root,30CKE@2|Bacteria,1V4BT@1239|Firmicutes,4HIQA@91061|Bacilli,1ZH08@1386|Bacillus 91061|Bacilli S Sigma-w pathway protein YsdB ysdB - - - - - - - - - - - - k141_32948_1 1123053.AUDG01000018_gene3019 1.06e-25 100.0 COG0745@1|root,COG0745@2|Bacteria,1RA00@1224|Proteobacteria,1S23N@1236|Gammaproteobacteria,1WYHV@135613|Chromatiales 135613|Chromatiales T Transcriptional regulatory protein, C terminal - - - - - - - - - - - - Response_reg,Trans_reg_C k141_32948_2 382464.ABSI01000020_gene212 1.13e-112 345.0 COG1629@1|root,COG4771@2|Bacteria 2|Bacteria P TonB-dependent receptor - - - - - - - - - - - - CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec k141_20023_1 1453501.JELR01000005_gene1763 3.66e-83 258.0 COG0536@1|root,COG0536@2|Bacteria,1MUGZ@1224|Proteobacteria,1RMFQ@1236|Gammaproteobacteria,4647H@72275|Alteromonadaceae 1236|Gammaproteobacteria S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control obg GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0007059,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0022607,GO:0022611,GO:0022613,GO:0022618,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0042254,GO:0042255,GO:0043021,GO:0043023,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0065003,GO:0065007,GO:0070925,GO:0071826,GO:0071840,GO:0090069,GO:0090071,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03979 - - - - ko00000,ko01000,ko03009 - - - GTP1_OBG,MMR_HSR1 k141_29430_1 218284.CCDN010000001_gene1029 3.08e-105 307.0 COG2057@1|root,COG2057@2|Bacteria,1TNY5@1239|Firmicutes,4HBFR@91061|Bacilli,1ZB4Q@1386|Bacillus 91061|Bacilli I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit scoB - 2.8.3.5 ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 - R00410 RC00014 ko00000,ko00001,ko01000 - - - CoA_trans k141_35522_1 218284.CCDN010000001_gene53 3.58e-111 335.0 COG1293@1|root,COG1293@2|Bacteria,1TQ8A@1239|Firmicutes,4H9UF@91061|Bacilli,1ZBGD@1386|Bacillus 91061|Bacilli K RNA-binding protein homologous to eukaryotic snRNP FbpA - - - - - - - - - - - DUF814,FbpA k141_5789_1 1196031.ALEG01000047_gene194 1.19e-52 173.0 COG1443@1|root,COG1443@2|Bacteria,1V6SB@1239|Firmicutes,4HJ2T@91061|Bacilli,1ZFNY@1386|Bacillus 91061|Bacilli I COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes M1-740 - - - - - - - - - - - NUDIX k141_29431_1 1348635.BBJY01000021_gene2859 3.93e-44 150.0 COG2165@1|root,COG2165@2|Bacteria,1N7HN@1224|Proteobacteria,1SDMJ@1236|Gammaproteobacteria,1XXUV@135623|Vibrionales 135623|Vibrionales NU Prokaryotic N-terminal methylation motif - - - ko:K10924 ko05111,map05111 - - - ko00000,ko00001,ko02044 - - - N_methyl k141_26068_1 218284.CCDN010000002_gene2855 2.51e-82 273.0 COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1TQ0B@1239|Firmicutes,4HA4G@91061|Bacilli,1ZBFF@1386|Bacillus 91061|Bacilli E glutamate synthase gltA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14,1.4.7.1 ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 - R00021,R00093,R00114,R00248,R10086 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - GATase_2,GXGXG,Glu_syn_central,Glu_synthase k141_9433_1 1116375.VEJY3_22151 4.64e-281 773.0 COG4097@1|root,COG4097@2|Bacteria,1MV9P@1224|Proteobacteria,1RR7V@1236|Gammaproteobacteria,1XUW4@135623|Vibrionales 135623|Vibrionales P FAD-binding domain - - - - - - - - - - - - FAD_binding_8,Ferric_reduct,NAD_binding_1 k141_9433_2 1116375.VEJY3_22156 1.03e-155 442.0 COG2367@1|root,COG2367@2|Bacteria,1NMW4@1224|Proteobacteria,1RWGW@1236|Gammaproteobacteria,1XUMT@135623|Vibrionales 135623|Vibrionales V Beta-lactamase - - 3.5.2.6 ko:K17836,ko:K19217 ko00311,ko01130,ko01501,map00311,map01130,map01501 M00627,M00628 R06363 RC01499 br01600,ko00000,ko00001,ko00002,ko01000,ko01504 - - - Beta-lactamase2 k141_9433_3 675806.VII_000729 8.53e-115 332.0 COG4977@1|root,COG4977@2|Bacteria,1QUTI@1224|Proteobacteria,1T352@1236|Gammaproteobacteria,1XTTX@135623|Vibrionales 135623|Vibrionales K DJ-1/PfpI family - - - - - - - - - - - - DJ-1_PfpI k141_9433_4 1198232.CYCME_1703 1.57e-72 221.0 COG0117@1|root,COG0117@2|Bacteria,1MUWT@1224|Proteobacteria,1RN2M@1236|Gammaproteobacteria,4604Z@72273|Thiotrichales 1236|Gammaproteobacteria H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate ribD - 1.1.1.193,3.5.4.26 ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 M00125 R03458,R03459 RC00204,RC00933 ko00000,ko00001,ko00002,ko01000 - - - RibD_C,dCMP_cyt_deam_1 k141_9433_5 1219065.VPR01S_35_00110 1.14e-145 411.0 COG0625@1|root,COG0625@2|Bacteria,1MY47@1224|Proteobacteria,1RRI3@1236|Gammaproteobacteria,1XW44@135623|Vibrionales 135623|Vibrionales O Belongs to the GST superfamily - - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C,GST_N k141_9433_8 1116375.VEJY3_20441 2.41e-280 772.0 COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,1RMHY@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator - - - ko:K11914 - - - - ko00000,ko02044,ko03000 - - - HTH_8,PAS,PAS_4,Sigma54_activat k141_31562_1 1294265.JCM21738_4749 2.1e-30 107.0 29SEG@1|root,30DJ8@2|Bacteria,1UBCJ@1239|Firmicutes,4IMRD@91061|Bacilli,1ZKP1@1386|Bacillus 91061|Bacilli S Spo0E like sporulation regulatory protein - - - ko:K06376 - - - - ko00000 - - - SpoOE-like k141_31562_2 1294265.JCM21738_4748 2.63e-80 242.0 COG0010@1|root,COG0010@2|Bacteria,1TR10@1239|Firmicutes,4HAT5@91061|Bacilli,1ZCJY@1386|Bacillus 91061|Bacilli E Belongs to the arginase family rocF GO:0003674,GO:0003824,GO:0004053,GO:0006082,GO:0006520,GO:0006525,GO:0006807,GO:0008150,GO:0008152,GO:0009064,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 3.5.3.1 ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 M00029,M00134 R00551 RC00024,RC00329 ko00000,ko00001,ko00002,ko01000 - - - Arginase k141_24751_1 218284.CCDN010000002_gene2880 2.19e-51 166.0 COG2318@1|root,COG2318@2|Bacteria,1V9AG@1239|Firmicutes,4HIWQ@91061|Bacilli,1ZR57@1386|Bacillus 91061|Bacilli S DinB superfamily - - - - - - - - - - - - DinB,DinB_2 k141_24751_2 218284.CCDN010000002_gene2879 2.6e-150 438.0 COG1001@1|root,COG1001@2|Bacteria,1TP84@1239|Firmicutes,4HBB2@91061|Bacilli,1ZCHI@1386|Bacillus 91061|Bacilli F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family ade GO:0003674,GO:0003824,GO:0006040,GO:0006044,GO:0006046,GO:0008150,GO:0008152,GO:0008448,GO:0009056,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0046348,GO:0071704,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901575 3.5.4.2 ko:K01486 ko00230,ko01100,map00230,map01100 - R01244 RC00477 ko00000,ko00001,ko01000 - - iYO844.BSU14520 Adenine_deam_C,Amidohydro_1 k141_20024_2 1538295.JY96_16850 3.11e-25 110.0 COG2267@1|root,COG2267@2|Bacteria,1RATF@1224|Proteobacteria,2WI63@28216|Betaproteobacteria,1KJSE@119065|unclassified Burkholderiales 28216|Betaproteobacteria I Alpha beta hydrolase - - - - - - - - - - - - Abhydrolase_1 k141_36735_2 1219076.N646_2875 1.92e-244 674.0 COG0772@1|root,COG0772@2|Bacteria,1MUK3@1224|Proteobacteria,1RMEJ@1236|Gammaproteobacteria,1XSC3@135623|Vibrionales 135623|Vibrionales M Peptidoglycan polymerase that is essential for cell wall elongation mrdB - - ko:K05837 - - - - ko00000,ko03036 - - - FTSW_RODA_SPOVE k141_36735_3 223926.28805706 1.08e-174 489.0 COG0797@1|root,COG0797@2|Bacteria,1MZ8S@1224|Proteobacteria,1RMCG@1236|Gammaproteobacteria,1XSTT@135623|Vibrionales 135623|Vibrionales M Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides rlpA - - ko:K03642 - - - - ko00000 - - - DPBB_1,SPOR k141_36735_4 674977.VMC_10260 7.66e-272 745.0 COG1686@1|root,COG1686@2|Bacteria,1MUU7@1224|Proteobacteria,1RMJA@1236|Gammaproteobacteria,1XSFX@135623|Vibrionales 135623|Vibrionales M Belongs to the peptidase S11 family dacA - 3.4.16.4 ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - PBP5_C,Peptidase_S11 k141_36735_5 1280001.BAOA01000003_gene3720 2.64e-56 175.0 COG2921@1|root,COG2921@2|Bacteria,1RGV5@1224|Proteobacteria,1S61Y@1236|Gammaproteobacteria,1XXUJ@135623|Vibrionales 135623|Vibrionales S Belongs to the UPF0250 family ybeD - - ko:K09158 - - - - ko00000 - - - DUF493 k141_36735_6 223926.28805703 2.05e-151 426.0 COG0321@1|root,COG0321@2|Bacteria,1MU6A@1224|Proteobacteria,1RMXQ@1236|Gammaproteobacteria,1XT77@135623|Vibrionales 135623|Vibrionales H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate lipB GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016874,GO:0016879,GO:0016979,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:0140096,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.3.1.181 ko:K03801 ko00785,ko01100,map00785,map01100 - R07766,R07769 RC00039,RC00992,RC02867 ko00000,ko00001,ko01000 - - - BPL_LplA_LipB k141_36735_7 1219076.N646_2870 6.41e-235 645.0 COG0320@1|root,COG0320@2|Bacteria,1MVRD@1224|Proteobacteria,1RMAT@1236|Gammaproteobacteria,1XUN7@135623|Vibrionales 135623|Vibrionales H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives lipA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 ko:K03644 ko00785,ko01100,map00785,map01100 - R07767,R07768 RC01978 ko00000,ko00001,ko01000 - - - LIAS_N,Radical_SAM k141_36735_8 223926.28805701 6.14e-297 810.0 COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,1RMHQ@1236|Gammaproteobacteria,1XTKA@135623|Vibrionales 135623|Vibrionales E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism glyA GO:0001505,GO:0003674,GO:0003824,GO:0004372,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006730,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016742,GO:0017144,GO:0019752,GO:0042133,GO:0042136,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 - - - SHMT k141_36735_9 1116375.VEJY3_03280 3.73e-132 376.0 COG1284@1|root,COG1284@2|Bacteria,1RDIV@1224|Proteobacteria,1RSIN@1236|Gammaproteobacteria,1XSE6@135623|Vibrionales 135623|Vibrionales S Uncharacterised 5xTM membrane BCR, YitT family COG1284 - - - - - - - - - - - - YitT_membrane k141_36735_10 1116375.VEJY3_03260 8.66e-128 363.0 COG0241@1|root,COG0241@2|Bacteria,1RDGR@1224|Proteobacteria,1S3UD@1236|Gammaproteobacteria,1XUHV@135623|Vibrionales 135623|Vibrionales E D,D-heptose 1,7-bisphosphate phosphatase gmhB GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914 3.1.3.82,3.1.3.83 ko:K03273 ko00540,ko01100,map00540,map01100 M00064 R05647,R09771 RC00017 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Hydrolase_like k141_36735_11 674977.VMC_06470 7.92e-227 627.0 COG1135@1|root,COG1135@2|Bacteria,1QTTK@1224|Proteobacteria,1RMQD@1236|Gammaproteobacteria,1XT41@135623|Vibrionales 135623|Vibrionales P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system metN GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0008150,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085 - ko:K02071 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - ABC_tran,NIL k141_36735_12 1116375.VEJY3_03250 2.97e-142 403.0 COG2011@1|root,COG2011@2|Bacteria,1MW8E@1224|Proteobacteria,1RQ6I@1236|Gammaproteobacteria,1XTTW@135623|Vibrionales 135623|Vibrionales P COG2011 ABC-type metal ion transport system, permease component metI GO:0000101,GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0015399,GO:0015405,GO:0015711,GO:0015821,GO:0015849,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0042623,GO:0042626,GO:0042940,GO:0043492,GO:0044464,GO:0046942,GO:0048473,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072348 - ko:K02072 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - BPD_transp_1 k141_31857_1 218284.CCDN010000002_gene2176 1.43e-108 323.0 28I6X@1|root,2Z89S@2|Bacteria,1TQMI@1239|Firmicutes,4HD5B@91061|Bacilli,1ZD3B@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF4350) - - - - - - - - - - - - DUF4350 k141_38018_1 1042377.AFPJ01000004_gene406 1.41e-138 418.0 COG1629@1|root,COG4771@2|Bacteria,1MUWN@1224|Proteobacteria,1RN1E@1236|Gammaproteobacteria,464FG@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec k141_31858_1 745277.GRAQ_02754 8.35e-75 233.0 COG1957@1|root,COG1957@2|Bacteria,1R49G@1224|Proteobacteria,1RZM4@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Belongs to the IUNH family - - - - - - - - - - - - IU_nuc_hydro k141_38019_1 218284.CCDN010000001_gene1008 4.81e-102 303.0 COG1234@1|root,COG1234@2|Bacteria,1TRGP@1239|Firmicutes,4HABM@91061|Bacilli,1ZC3J@1386|Bacillus 91061|Bacilli S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA rnz GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0042802,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 3.1.26.11 ko:K00784 ko03013,map03013 - - - ko00000,ko00001,ko01000,ko03016 - - - Lactamase_B,Lactamase_B_2 k141_30740_1 1453501.JELR01000001_gene2476 3.87e-123 381.0 COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,1RNCU@1236|Gammaproteobacteria,464IX@72275|Alteromonadaceae 1236|Gammaproteobacteria L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd GO:0000715,GO:0000716,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006283,GO:0006289,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008094,GO:0008150,GO:0008152,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0015616,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031326,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0043175,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051276,GO:0051716,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF k141_28500_1 1201293.AKXQ01000009_gene944 5.49e-29 108.0 2EA5D@1|root,334A9@2|Bacteria,1NE5M@1224|Proteobacteria,1SFTI@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Regulator of ribonuclease activity B - - - - - - - - - - - - RraB k141_28500_2 243159.AFE_3169 4.77e-41 140.0 COG3837@1|root,COG3837@2|Bacteria,1R9WZ@1224|Proteobacteria,1S63W@1236|Gammaproteobacteria 1236|Gammaproteobacteria S conserved protein, contains double-stranded beta-helix domain - - - - - - - - - - - - Cupin_2 k141_30741_1 42565.FP66_04325 1.62e-63 195.0 COG3098@1|root,COG3098@2|Bacteria,1N7AG@1224|Proteobacteria,1SCXJ@1236|Gammaproteobacteria,1XKZQ@135619|Oceanospirillales 135619|Oceanospirillales S protein conserved in bacteria - - - - - - - - - - - - DUF446 k141_30741_2 42565.FP66_04330 6.3e-23 91.3 COG2105@1|root,COG2105@2|Bacteria,1N3EK@1224|Proteobacteria,1SA6J@1236|Gammaproteobacteria,1XMK7@135619|Oceanospirillales 135619|Oceanospirillales S Gamma-glutamyl cyclotransferase, AIG2-like - - - - - - - - - - - - GGACT k141_8261_1 1042377.AFPJ01000021_gene2128 7.29e-108 328.0 COG0122@1|root,COG2169@1|root,COG0122@2|Bacteria,COG2169@2|Bacteria,1QTXM@1224|Proteobacteria,1RNQB@1236|Gammaproteobacteria,464XA@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG2169 Adenosine deaminase ada - 3.2.2.21 ko:K01247,ko:K13529 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03000,ko03400 - - - Ada_Zn_binding,AlkA_N,HTH_18,HhH-GPD k141_31860_1 218284.CCDN010000005_gene3244 1.51e-103 312.0 COG0004@1|root,COG0004@2|Bacteria,1TQYG@1239|Firmicutes,4HBGK@91061|Bacilli,1ZB5S@1386|Bacillus 91061|Bacilli P Ammonium transporter amtB - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - Ammonium_transp k141_30742_1 1196031.ALEG01000042_gene2307 1.5e-112 338.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,4HA38@91061|Bacilli,1ZBKJ@1386|Bacillus 91061|Bacilli O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions groL GO:0001817,GO:0001819,GO:0001871,GO:0002791,GO:0002793,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009986,GO:0009987,GO:0016465,GO:0030246,GO:0030247,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044764,GO:0046812,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051082,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051704,GO:0061077,GO:0065007,GO:0070201,GO:0090087,GO:0098630,GO:0098743,GO:0101031,GO:1903530,GO:1903532,GO:1904951,GO:1990220,GO:2000482,GO:2000484,GO:2001065 - ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 - - - Cpn60_TCP1 k141_28501_1 1279017.AQYJ01000027_gene1999 1.56e-21 93.2 COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,1RMW3@1236|Gammaproteobacteria,463Y1@72275|Alteromonadaceae 1236|Gammaproteobacteria G Belongs to the pyruvate kinase family pykA GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016043,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - e_coli_core.b1854,iAF1260.b1854,iB21_1397.B21_01813,iBWG_1329.BWG_1668,iEC042_1314.EC042_2021,iECBD_1354.ECBD_1784,iECB_1328.ECB_01825,iECDH10B_1368.ECDH10B_1995,iECDH1ME8569_1439.ECDH1ME8569_1801,iECD_1391.ECD_01825,iECO103_1326.ECO103_2044,iECO111_1330.ECO111_2362,iECO26_1355.ECO26_2692,iECUMN_1333.ECUMN_2152,iETEC_1333.ETEC_1887,iEcDH1_1363.EcDH1_1786,iEcE24377_1341.EcE24377A_2084,iEcHS_1320.EcHS_A1947,iEcSMS35_1347.EcSMS35_1332,iEcolC_1368.EcolC_1778,iG2583_1286.G2583_2306,iJO1366.b1854,iJR904.b1854,iSBO_1134.SBO_1162,iSSON_1240.SSON_1294,iSbBS512_1146.SbBS512_E2130,iUMNK88_1353.UMNK88_2326,iY75_1357.Y75_RS09740 PK,PK_C k141_8264_1 42565.FP66_11655 1.17e-58 196.0 COG0471@1|root,COG0569@1|root,COG0471@2|Bacteria,COG0569@2|Bacteria,1MU0K@1224|Proteobacteria,1RMI1@1236|Gammaproteobacteria,1XHSW@135619|Oceanospirillales 135619|Oceanospirillales P COG0471 Di- and tricarboxylate transporters - - - - - - - - - - - - CitMHS,TrkA_C k141_31863_1 675817.VDA_001033 3.48e-39 149.0 COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,1RNB7@1236|Gammaproteobacteria,1XTUF@135623|Vibrionales 135623|Vibrionales S metal-dependent hydrolase with the TIM-barrel fold - - - - - - - - - - - - Amidohydro_3 k141_28502_1 218284.CCDN010000001_gene1014 1.46e-80 248.0 COG0491@1|root,COG0491@2|Bacteria,1TQPX@1239|Firmicutes,4HAV6@91061|Bacilli,1ZCFS@1386|Bacillus 91061|Bacilli S COG0491 Zn-dependent hydrolases, including glyoxylases yqjP - - - - - - - - - - - Lactamase_B k141_38020_1 1116375.VEJY3_21861 8.43e-119 350.0 2C2F5@1|root,32WND@2|Bacteria,1R7B4@1224|Proteobacteria,1RZJV@1236|Gammaproteobacteria,1XTNW@135623|Vibrionales 135623|Vibrionales - - VPA0561 - - - - - - - - - - - - k141_38020_2 223926.28808726 1.66e-154 435.0 COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,1S4GN@1236|Gammaproteobacteria,1Y2TK@135623|Vibrionales 135623|Vibrionales V abc transporter atp-binding protein - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_38020_3 1116375.VEJY3_21871 2.18e-237 659.0 COG4591@1|root,COG4591@2|Bacteria,1R4Q2@1224|Proteobacteria,1S7I9@1236|Gammaproteobacteria,1XU7J@135623|Vibrionales 135623|Vibrionales M MacB-like periplasmic core domain VPA0559 - - - - - - - - - - - FtsX,MacB_PCD k141_38020_4 223926.28808724 1.65e-59 195.0 COG4591@1|root,COG4591@2|Bacteria,1R4Q2@1224|Proteobacteria,1S1AK@1236|Gammaproteobacteria,1XVHA@135623|Vibrionales 135623|Vibrionales M FtsX-like permease family VPA0558 - - - - - - - - - - - FtsX,MacB_PCD k141_36742_1 265729.GS18_0219445 5.17e-31 119.0 COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli,1ZB5X@1386|Bacillus 91061|Bacilli G phosphotransferase system treP GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0015766,GO:0015771,GO:0015772,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563,GO:0090589 2.7.1.201 ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 M00270 R02780 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.13,4.A.1.2.4,4.A.1.2.8 - iYO844.BSU07800 PTS_EIIA_1,PTS_EIIB,PTS_EIIC k141_8266_1 1121930.AQXG01000007_gene423 1.65e-07 54.7 COG2911@1|root,COG4677@1|root,COG2911@2|Bacteria,COG4677@2|Bacteria 2|Bacteria G pectinesterase activity - - 3.2.1.51,4.2.2.23 ko:K10297,ko:K15923,ko:K18197,ko:K20276 ko00511,ko02024,map00511,map02024 - - - ko00000,ko00001,ko01000,ko04121 - GH95,PL11 - Beta_helix,CHU_C k141_31865_2 1385511.N783_19675 9.14e-75 240.0 COG0477@1|root,COG2814@2|Bacteria,1VSW8@1239|Firmicutes,4HUQC@91061|Bacilli,2YBCJ@289201|Pontibacillus 91061|Bacilli U Belongs to the major facilitator superfamily bmr3 - - - - - - - - - - - MFS_1 k141_30745_3 218284.CCDN010000001_gene772 4.39e-22 92.4 COG1284@1|root,COG1284@2|Bacteria,1TQTP@1239|Firmicutes,4HBV2@91061|Bacilli,1ZCF3@1386|Bacillus 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2179) yqfU - - - - - - - - - - - DUF2179,YitT_membrane k141_36744_1 768066.HELO_3395 2.32e-46 154.0 2E214@1|root,32X90@2|Bacteria,1N3TR@1224|Proteobacteria,1SB5W@1236|Gammaproteobacteria,1XKKV@135619|Oceanospirillales 135619|Oceanospirillales S Phasin protein - - - - - - - - - - - - Phasin_2 k141_15386_1 1308866.J416_15672 1.06e-152 440.0 COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,4HB0P@91061|Bacilli,471IY@74385|Gracilibacillus 91061|Bacilli L Transposase, Mutator family - - - - - - - - - - - - Transposase_mut k141_38021_1 1453501.JELR01000002_gene372 6.99e-100 298.0 COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,1RM8I@1236|Gammaproteobacteria,466HI@72275|Alteromonadaceae 1236|Gammaproteobacteria G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) tpiA GO:0003674,GO:0003824,GO:0004807,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01015 RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 - - iJN746.PP_4715 TIM k141_30746_1 743719.PaelaDRAFT_4959 1.87e-40 144.0 COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,4HATK@91061|Bacilli,26QJP@186822|Paenibacillaceae 91061|Bacilli I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids fabH - 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACP_syn_III,ACP_syn_III_C k141_31867_1 218284.CCDN010000007_gene3853 2.07e-58 186.0 COG1136@1|root,COG1136@2|Bacteria,1TNZG@1239|Firmicutes,4H9UT@91061|Bacilli,1ZCDW@1386|Bacillus 91061|Bacilli V ABC transporter, ATP-binding protein bceA - - ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 M00258,M00314,M00730,M00732,M00737,M00738 - - ko00000,ko00001,ko00002,ko01504,ko02000 3.A.1,3.A.1.134.3,3.A.1.134.7 - - ABC_tran k141_31867_2 218284.CCDN010000007_gene3852 3.58e-43 155.0 COG0577@1|root,COG0577@2|Bacteria,1TR2D@1239|Firmicutes,4H9SH@91061|Bacilli,1ZBJC@1386|Bacillus 91061|Bacilli V ABC transporter (permease) bceB - - ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 M00314,M00730,M00732,M00737,M00738 - - ko00000,ko00001,ko00002,ko01504,ko02000 3.A.1.134.3,3.A.1.134.7 - - FtsX k141_38022_1 1116375.VEJY3_21971 2.17e-115 345.0 COG1109@1|root,COG1109@2|Bacteria,1QUGD@1224|Proteobacteria,1RQME@1236|Gammaproteobacteria,1XVES@135623|Vibrionales 135623|Vibrionales G Phosphoglucomutase phosphomannomutase alpha beta subunit - - 5.4.2.8 ko:K01840 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 M00114 R01818 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV k141_38022_2 1280001.BAOA01000136_gene1967 3.17e-79 237.0 COG0454@1|root,COG0456@2|Bacteria,1N6QA@1224|Proteobacteria,1SDXW@1236|Gammaproteobacteria,1XXM6@135623|Vibrionales 135623|Vibrionales K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10 k141_36746_1 218284.CCDN010000002_gene2157 4.03e-97 290.0 COG1609@1|root,COG1609@2|Bacteria,1TRFH@1239|Firmicutes,4HE9A@91061|Bacilli,1ZQ1D@1386|Bacillus 91061|Bacilli K helix_turn _helix lactose operon repressor - - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 k141_8267_1 392499.Swit_1656 1.38e-56 213.0 COG4773@1|root,COG4773@2|Bacteria,1QTXJ@1224|Proteobacteria,2TUFQ@28211|Alphaproteobacteria,2K1E5@204457|Sphingomonadales 204457|Sphingomonadales P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec k141_30749_1 1122176.KB903545_gene903 4.53e-32 123.0 COG2120@1|root,COG2120@2|Bacteria,4NEDJ@976|Bacteroidetes,1INQT@117747|Sphingobacteriia 976|Bacteroidetes S GlcNAc-PI de-N-acetylase bshB1 - - ko:K01463 - - - - ko00000,ko01000 - - - PIG-L k141_30749_2 1042376.AFPK01000067_gene814 1.18e-09 58.2 COG0438@1|root,COG0438@2|Bacteria,4NFPA@976|Bacteroidetes,1HWYY@117743|Flavobacteriia,405X2@61432|unclassified Flavobacteriaceae 976|Bacteroidetes M Glycosyl transferase 4-like bshA - - ko:K00754 - - - - ko00000,ko01000 - GT4 - Glyco_transf_4,Glycos_transf_1 k141_8268_1 1453501.JELR01000001_gene1901 4.23e-72 232.0 COG2114@1|root,COG2114@2|Bacteria,1MV1V@1224|Proteobacteria,1SZ0N@1236|Gammaproteobacteria,46CIY@72275|Alteromonadaceae 1236|Gammaproteobacteria T Adenylyl- / guanylyl cyclase, catalytic domain - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_cyc,HAMP k141_30750_1 218284.CCDN010000001_gene680 4.04e-121 356.0 COG2256@1|root,COG2256@2|Bacteria,1TPVV@1239|Firmicutes,4HAIS@91061|Bacilli,1ZBCW@1386|Bacillus 91061|Bacilli L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase rarA - - ko:K07478 - - - - ko00000 - - - AAA,AAA_assoc_2,MgsA_C,RuvB_N k141_32048_2 406124.ACPC01000009_gene1569 1.7e-87 259.0 COG0450@1|root,COG0450@2|Bacteria,1TQU7@1239|Firmicutes,4HA2M@91061|Bacilli,1ZCZP@1386|Bacillus 91061|Bacilli O Alkyl hydroperoxide reductase ykuU - - - - - - - - - - - 1-cysPrx_C,AhpC-TSA k141_30903_1 42565.FP66_03905 1.42e-142 422.0 COG2838@1|root,COG2838@2|Bacteria,1MV6Q@1224|Proteobacteria,1RPG4@1236|Gammaproteobacteria,1XHUH@135619|Oceanospirillales 135619|Oceanospirillales C Isocitrate dehydrogenase - - 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 - - - IDH k141_32049_1 218284.CCDN010000005_gene3228 5.41e-269 771.0 COG3857@1|root,COG3857@2|Bacteria,1TQJW@1239|Firmicutes,4HAY6@91061|Bacilli,1ZC70@1386|Bacillus 91061|Bacilli L ATP-dependent helicase deoxyribonuclease subunit B rexB GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0004527,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.6.4.12 ko:K16899 - - - - ko00000,ko01000,ko03400 - - - Exonuc_V_gamma,PDDEXK_1,UvrD_C k141_30904_1 745014.OMB55_00016780 1.16e-14 75.1 COG3104@1|root,COG3104@2|Bacteria,1R5E8@1224|Proteobacteria,1RQR0@1236|Gammaproteobacteria,1J97X@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E POT family - - - - - - - - - - - - MFS_1 k141_30904_2 1123053.AUDG01000002_gene2879 4.57e-10 62.0 COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,1RYKI@1236|Gammaproteobacteria 1236|Gammaproteobacteria E aminopeptidase ypdF GO:0003674,GO:0003824,GO:0004177,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.11.9 ko:K01262,ko:K08326 - - - - ko00000,ko01000,ko01002 - - - Creatinase_N,Peptidase_M24 k141_30906_1 1284352.AOIG01000013_gene3553 1.16e-76 248.0 COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,4HBD3@91061|Bacilli,26RCD@186822|Paenibacillaceae 91061|Bacilli G ABC-type sugar transport system, ATPase component rbsA3 - 3.6.3.17 ko:K02056 - M00221 - - ko00000,ko00002,ko01000,ko02000 3.A.1.2 - - ABC_tran k141_32056_1 218284.CCDN010000007_gene4013 2.02e-80 247.0 COG2385@1|root,COG2385@2|Bacteria,1TQSI@1239|Firmicutes,4HCE3@91061|Bacilli,1ZBNU@1386|Bacillus 91061|Bacilli D Stage II sporulation protein D spoIID GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 - ko:K06381 - - - - ko00000 - - - SpoIID k141_30912_1 1294265.JCM21738_460 1.59e-111 323.0 COG0243@1|root,COG0243@2|Bacteria,1UYJX@1239|Firmicutes,4HE4J@91061|Bacilli 91061|Bacilli C belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - - - - - - - - - - Molybdopterin,Molydop_binding k141_32059_2 1279017.AQYJ01000026_gene265 6.7e-74 236.0 COG0438@1|root,COG0438@2|Bacteria,1NA28@1224|Proteobacteria,1RQBV@1236|Gammaproteobacteria,4668K@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0438 Glycosyltransferase - - - - - - - - - - - - DUF3524,Glyco_trans_1_4,Glycos_transf_1 k141_32061_1 218284.CCDN010000002_gene2012 2.32e-136 397.0 COG3180@1|root,COG3180@2|Bacteria,1UVXN@1239|Firmicutes,4HDRW@91061|Bacilli,1ZDNB@1386|Bacillus 91061|Bacilli S membrane - - - ko:K07120 - - - - ko00000 - - - AbrB k141_32062_1 1042377.AFPJ01000009_gene199 2.59e-107 318.0 COG3047@1|root,COG3047@2|Bacteria 2|Bacteria - - ompW - - ko:K07275 - - - - ko00000 - - - OmpW k141_32063_2 218284.CCDN010000005_gene3408 4.65e-123 354.0 2DBQ9@1|root,2ZACY@2|Bacteria,1V0WH@1239|Firmicutes,4HEH4@91061|Bacilli,1ZR7V@1386|Bacillus 91061|Bacilli S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) yutC - - - - - - - - - - - Spore_YhcN_YlaJ k141_32064_1 315750.BPUM_2794 5.47e-55 185.0 COG2070@1|root,COG2070@2|Bacteria,1TPC3@1239|Firmicutes,4H9T0@91061|Bacilli,1ZBXS@1386|Bacillus 91061|Bacilli S COG2070 Dioxygenases related to 2-nitropropane dioxygenase npd - 1.13.12.16 ko:K00459 ko00910,map00910 - R00025 RC02541,RC02759 ko00000,ko00001,ko01000 - - - NMO k141_32066_1 1247024.JRLH01000016_gene1680 5.6e-07 48.9 2EMPC@1|root,33FBT@2|Bacteria,1QNQV@1224|Proteobacteria,1SI44@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_32067_1 218284.CCDN010000009_gene4315 1.12e-147 434.0 COG0601@1|root,COG1173@1|root,COG0601@2|Bacteria,COG1173@2|Bacteria,1V21B@1239|Firmicutes,4HDPU@91061|Bacilli,1ZEQ7@1386|Bacillus 91061|Bacilli EP Binding-protein-dependent transport system inner membrane component - - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1,Peptidase_M1 k141_32069_1 1453501.JELR01000001_gene2506 4.61e-61 197.0 28M8G@1|root,2ZAMM@2|Bacteria,1MVBT@1224|Proteobacteria,1RMAM@1236|Gammaproteobacteria,467EP@72275|Alteromonadaceae 1236|Gammaproteobacteria S RES - - - - - - - - - - - - RES k141_32071_1 1294265.JCM21738_2727 3.34e-36 125.0 COG2041@1|root,COG2041@2|Bacteria,1V1EZ@1239|Firmicutes,4HIWI@91061|Bacilli,1ZDPV@1386|Bacillus 91061|Bacilli S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide ylaL - - - - - - - - - - - - k141_32071_2 1294265.JCM21738_2728 1.71e-57 178.0 COG4838@1|root,COG4838@2|Bacteria,1VAXB@1239|Firmicutes,4HKIX@91061|Bacilli,1ZI2B@1386|Bacillus 91061|Bacilli S Belongs to the UPF0358 family ylaN - - - - - - - - - - - DUF1507 k141_32076_3 1279017.AQYJ01000013_gene2990 1.02e-123 352.0 COG0250@1|root,COG0250@2|Bacteria,1MU14@1224|Proteobacteria,1RMW0@1236|Gammaproteobacteria,4644G@72275|Alteromonadaceae 1236|Gammaproteobacteria K Participates in transcription elongation, termination and antitermination nusG GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - ko:K02601 - - - - ko00000,ko03009,ko03021 - - - KOW,NusG k141_32076_5 1453501.JELR01000005_gene1711 3.88e-146 414.0 COG0081@1|root,COG0081@2|Bacteria,1MUE6@1224|Proteobacteria,1RMDW@1236|Gammaproteobacteria,4649G@72275|Alteromonadaceae 1236|Gammaproteobacteria J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release rplA GO:0000027,GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006417,GO:0006446,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016043,GO:0016070,GO:0016072,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045947,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - ko:K02863 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L1 k141_32078_1 218284.CCDN010000001_gene1496 1.49e-86 259.0 COG0344@1|root,COG0344@2|Bacteria,1VA3J@1239|Firmicutes,4HC55@91061|Bacilli,1ZFP9@1386|Bacillus 91061|Bacilli I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP plsY - 2.3.1.15 ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - G3P_acyltransf k141_32079_1 218284.CCDN010000002_gene2488 4.73e-46 157.0 COG0119@1|root,COG0119@2|Bacteria,1TS0A@1239|Firmicutes,4HAXZ@91061|Bacilli,1ZARP@1386|Bacillus 91061|Bacilli E Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds dmpG - 4.1.3.39 ko:K01666 ko00360,ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00360,map00362,map00621,map00622,map01100,map01120,map01220 M00545,M00569 R00750 RC00307,RC00371 br01602,ko00000,ko00001,ko00002,ko01000 - - - DmpG_comm,HMGL-like k141_32081_1 29495.EA26_04615 8.63e-26 95.1 2AWMP@1|root,31NIE@2|Bacteria,1QK92@1224|Proteobacteria,1TICH@1236|Gammaproteobacteria,1XYVD@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF3149) - - - - - - - - - - - - DUF3149 k141_32081_2 223926.28805737 3.9e-129 367.0 COG2840@1|root,COG2840@2|Bacteria,1RH34@1224|Proteobacteria,1S6B5@1236|Gammaproteobacteria,1XT93@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria - - - - - - - - - - - - Smr k141_32081_3 1116375.VEJY3_03450 1.24e-237 655.0 COG1187@1|root,COG1187@2|Bacteria,1MXQE@1224|Proteobacteria,1RMC7@1236|Gammaproteobacteria,1XTHG@135623|Vibrionales 135623|Vibrionales J Belongs to the pseudouridine synthase RsuA family rluF - 5.4.99.21 ko:K06182 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 k141_32081_4 1116375.VEJY3_03445 2.13e-104 302.0 COG2606@1|root,COG2606@2|Bacteria,1RGX5@1224|Proteobacteria,1S6S0@1236|Gammaproteobacteria,1XX0H@135623|Vibrionales 135623|Vibrionales S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily ybaK - - ko:K03976 - - - - ko00000,ko01000,ko03016 - - - tRNA_edit k141_32081_5 1280001.BAOA01000095_gene4333 1.38e-296 816.0 COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,1RPX3@1236|Gammaproteobacteria,1XUQ9@135623|Vibrionales 135623|Vibrionales F Belongs to the 5'-nucleotidase family ushA GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0009225,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034641,GO:0042578,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901360 3.1.3.5,3.6.1.45 ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - 5_nucleotid_C,Metallophos k141_32084_1 218284.CCDN010000007_gene3970 2.46e-137 390.0 COG0176@1|root,COG0176@2|Bacteria,1TP4Q@1239|Firmicutes,4HA8G@91061|Bacilli,1ZCA6@1386|Bacillus 91061|Bacilli G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway tal GO:0003674,GO:0005488,GO:0005515,GO:0042802 2.2.1.2 ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01827 RC00439,RC00604 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU37110 TAL_FSA k141_32085_1 42565.FP66_15405 6.46e-124 367.0 COG0155@1|root,COG0155@2|Bacteria,1MVVB@1224|Proteobacteria,1RMFH@1236|Gammaproteobacteria,1XHUA@135619|Oceanospirillales 135619|Oceanospirillales C Sulfite reductase cysI - 1.8.1.2 ko:K00381 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00176 R00858 RC00065 ko00000,ko00001,ko00002,ko01000 - - - NIR_SIR,NIR_SIR_ferr k141_32087_2 1453501.JELR01000001_gene1894 0.0 934.0 COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,1RP81@1236|Gammaproteobacteria,4657S@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the synthesis of GMP from XMP guaA GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 - - iJN746.PP_1032,iSF_1195.SF2553,iSFxv_1172.SFxv_2808,iS_1188.S2725,iYL1228.KPN_02833 GATase,GMP_synt_C,NAD_synthase k141_32087_3 247639.MGP2080_03380 4.58e-11 63.2 2EITU@1|root,33CJ4@2|Bacteria,1NMF7@1224|Proteobacteria,1SI8Z@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_32087_4 1453501.JELR01000001_gene1902 1.6e-117 343.0 28HUI@1|root,2Z818@2|Bacteria,1P2BF@1224|Proteobacteria,1RQM2@1236|Gammaproteobacteria,465PQ@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_32088_1 218284.CCDN010000002_gene2138 5.08e-108 323.0 COG3844@1|root,COG3844@2|Bacteria,1TQ8V@1239|Firmicutes,4HBE8@91061|Bacilli,1ZBCN@1386|Bacillus 91061|Bacilli E Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively kynU GO:0003674,GO:0003824,GO:0016787,GO:0016822,GO:0016823,GO:0030429 3.7.1.3 ko:K01556 ko00380,ko01100,map00380,map01100 M00038 R00987,R02668,R03936 RC00284,RC00415 ko00000,ko00001,ko00002,ko01000 - - - Aminotran_5 k141_32089_1 218284.CCDN010000001_gene1488 2.51e-45 159.0 COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,4H9SZ@91061|Bacilli,1ZAX7@1386|Bacillus 91061|Bacilli E Sodium alanine symporter glnT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03310,ko:K11626 ko02020,map02020 - - - ko00000,ko00001 2.A.25 - - Na_Ala_symp k141_32089_2 218284.CCDN010000001_gene1487 3.77e-128 370.0 2DPHP@1|root,32UM5@2|Bacteria,1VBTA@1239|Firmicutes,4HKSX@91061|Bacilli,1ZBMR@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_32092_1 1453501.JELR01000002_gene639 2.55e-135 388.0 COG0384@1|root,COG0384@2|Bacteria,1MUAS@1224|Proteobacteria,1RPWM@1236|Gammaproteobacteria,467X3@72275|Alteromonadaceae 1236|Gammaproteobacteria S Phenazine biosynthesis-like protein - - 5.3.3.17 ko:K06998 ko00405,ko01130,ko02024,map00405,map01130,map02024 M00835 - - ko00000,ko00001,ko00002,ko01000 - - - PhzC-PhzF k141_32094_1 218284.CCDN010000002_gene1988 2.24e-92 291.0 COG0046@1|root,COG0046@2|Bacteria,1TPAS@1239|Firmicutes,4HB3N@91061|Bacilli,1ZCN8@1386|Bacillus 91061|Bacilli F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL purL GO:0003674,GO:0003824,GO:0004642,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C k141_32098_2 935836.JAEL01000007_gene2899 4.87e-21 89.7 COG0179@1|root,COG0179@2|Bacteria,1UZ6U@1239|Firmicutes,4HCE0@91061|Bacilli,1ZARQ@1386|Bacillus 91061|Bacilli Q Domain of unknown function (DUF2437) - - - - - - - - - - - - DUF2437,FAA_hydrolase k141_32101_2 441769.ABFU01000002_gene2966 4.29e-65 203.0 COG1428@1|root,COG1428@2|Bacteria,1TPJ1@1239|Firmicutes,4HA9N@91061|Bacilli,1ZBFB@1386|Bacillus 91061|Bacilli F Deoxycytidine kinase dck - 2.7.1.74,2.7.1.76 ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 - R00185,R01666,R02089 RC00002,RC00017 ko00000,ko00001,ko01000 - - - dNK k141_32102_1 42565.FP66_05670 5.44e-164 468.0 COG1593@1|root,COG1593@2|Bacteria,1MUQE@1224|Proteobacteria,1RY6X@1236|Gammaproteobacteria,1XIYZ@135619|Oceanospirillales 135619|Oceanospirillales G Malonyl-CoA decarboxylase - - 4.1.1.9 ko:K01578 ko00410,ko00640,ko01100,ko04146,ko04152,map00410,map00640,map01100,map04146,map04152 - R00233 RC00040 ko00000,ko00001,ko01000 - - - MCD,MCD_N k141_10713_2 1042377.AFPJ01000008_gene2007 8.81e-251 696.0 COG0477@1|root,COG2814@2|Bacteria,1PR3J@1224|Proteobacteria,1RPWR@1236|Gammaproteobacteria 1236|Gammaproteobacteria EGP Major facilitator superfamily - - - - - - - - - - - - MFS_1,Sugar_tr k141_10713_3 247634.GPB2148_1405 4.46e-115 338.0 COG4221@1|root,COG4221@2|Bacteria,1RF5D@1224|Proteobacteria,1S5AC@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short k141_10713_4 1042377.AFPJ01000008_gene2008 2.08e-75 241.0 COG0388@1|root,COG0388@2|Bacteria,1MXG5@1224|Proteobacteria 1224|Proteobacteria T Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - - - - - - - - - - CN_hydrolase k141_33470_3 218284.CCDN010000001_gene1565 5.52e-15 70.1 COG0454@1|root,COG0456@2|Bacteria,1V86G@1239|Firmicutes,4HJIA@91061|Bacilli,1ZH6Y@1386|Bacillus 91061|Bacilli K Acetyltransferase (GNAT) family - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10 k141_25170_1 1294265.JCM21738_3633 3.17e-08 51.6 COG1294@1|root,COG1294@2|Bacteria,1TRYV@1239|Firmicutes,4H9KF@91061|Bacilli,1ZDGQ@1386|Bacillus 91061|Bacilli C Cytochrome d ubiquinol oxidase, subunit II cydB - 1.10.3.14 ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - Cyt_bd_oxida_II k141_25170_2 1294265.JCM21738_3632 2.65e-107 320.0 COG1271@1|root,COG1271@2|Bacteria,1TRH4@1239|Firmicutes,4HA19@91061|Bacilli,1ZBAG@1386|Bacillus 91061|Bacilli C oxidase, subunit cydA2 - 1.10.3.14 ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - Cyt_bd_oxida_I k141_26418_3 1279017.AQYJ01000029_gene3690 9.88e-55 172.0 COG0023@1|root,COG0023@2|Bacteria,1MZ8T@1224|Proteobacteria,1S929@1236|Gammaproteobacteria,4689G@72275|Alteromonadaceae 1236|Gammaproteobacteria J Translation initiation factor yciH GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K03113 ko03013,map03013 - - - ko00000,ko00001,ko03012 - - - SUI1 k141_21648_1 935836.JAEL01000054_gene4840 2.2e-38 134.0 COG2094@1|root,COG2094@2|Bacteria,1V1E6@1239|Firmicutes,4HG5E@91061|Bacilli,1ZFWT@1386|Bacillus 91061|Bacilli L Belongs to the DNA glycosylase MPG family yxlJ GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.2.2.21 ko:K03652 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Pur_DNA_glyco k141_21648_2 218284.CCDN010000009_gene4314 4.73e-65 205.0 COG2200@1|root,COG2200@2|Bacteria,1V6YK@1239|Firmicutes,4HIIM@91061|Bacilli,1ZH5W@1386|Bacillus 91061|Bacilli T Putative diguanylate phosphodiesterase - - - - - - - - - - - - EAL k141_6253_1 218284.CCDN010000005_gene3197 3.38e-78 252.0 COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,4H9T9@91061|Bacilli,1ZBH0@1386|Bacillus 91061|Bacilli S YhgE Pip N-terminal domain protein yhgE - - ko:K01421 - - - - ko00000 - - - ABC2_membrane_3,DUF3533 k141_2616_2 223926.28807338 2.13e-88 263.0 COG0782@1|root,COG0782@2|Bacteria,1MYZ9@1224|Proteobacteria,1S2JD@1236|Gammaproteobacteria,1Y2YC@135623|Vibrionales 135623|Vibrionales K Transcription elongation factor, GreA/GreB, C-term - - - - - - - - - - - - GreA_GreB k141_12126_1 406124.ACPC01000049_gene118 1.33e-21 89.4 2E9K1@1|root,30BV2@2|Bacteria,1U8Q3@1239|Firmicutes,4IIN7@91061|Bacilli,1ZPB5@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_14494_1 1122228.AQXR01000010_gene1074 3.33e-14 73.2 COG1066@1|root,COG1066@2|Bacteria,2GMQ0@201174|Actinobacteria,4CZE1@85004|Bifidobacteriales 201174|Actinobacteria O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function radA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K04485 - - - - ko00000,ko03400 - - - AAA_25,ATPase,ChlI,Lon_C k141_14494_2 1121459.AQXE01000001_gene2625 5.04e-72 234.0 COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,42M7X@68525|delta/epsilon subdivisions,2WJCA@28221|Deltaproteobacteria,2M7ZB@213115|Desulfovibrionales 28221|Deltaproteobacteria L it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k141_25171_1 1279017.AQYJ01000019_gene1521 2.85e-95 305.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,464CD@72275|Alteromonadaceae 1236|Gammaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family mtrD_1 - - ko:K18138,ko:K18307 ko01501,ko01503,ko02024,map01501,map01503,map02024 M00644,M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2,2.A.6.2.20,2.A.6.2.32 - - ACR_tran k141_16834_1 1042377.AFPJ01000008_gene2002 4.33e-103 306.0 COG0119@1|root,COG0119@2|Bacteria,1MUMX@1224|Proteobacteria,1RMUX@1236|Gammaproteobacteria,469DW@72275|Alteromonadaceae 1236|Gammaproteobacteria E HMGL-like - - 4.1.3.4 ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 M00036,M00088 R01360,R08090 RC00502,RC00503,RC01118,RC01946 ko00000,ko00001,ko00002,ko01000 - - - HMGL-like k141_15684_1 218284.CCDN010000001_gene1218 9.79e-47 160.0 COG0454@1|root,COG0456@2|Bacteria,1V4AF@1239|Firmicutes,4HD36@91061|Bacilli,1ZCVH@1386|Bacillus 91061|Bacilli K Acetyltransferase (GNAT) family yodP - 2.3.1.264 ko:K21935 - - R11701 - ko00000,ko01000 - - - Acetyltransf_1,Acetyltransf_9 k141_26419_1 523791.Kkor_1005 4.5e-13 76.3 COG4257@1|root,COG4257@2|Bacteria,1QR8W@1224|Proteobacteria,1RQM4@1236|Gammaproteobacteria,1XPTW@135619|Oceanospirillales 135619|Oceanospirillales V Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid - - - ko:K18235 - - - - ko00000,ko01000,ko01504 - - - - k141_28788_1 218284.CCDN010000002_gene2077 1.2e-92 282.0 COG0665@1|root,COG0665@2|Bacteria,1TQTF@1239|Firmicutes,4HA0F@91061|Bacilli,1ZBU6@1386|Bacillus 91061|Bacilli E COG0665 Glycine D-amino acid oxidases (deaminating) yurR GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0044424,GO:0044464,GO:0055114 1.4.5.1 ko:K00285 ko00360,map00360 - R01374,R09493 RC00006,RC00025 ko00000,ko00001,ko01000 - - - DAO k141_13304_1 1116375.VEJY3_02560 7.22e-216 602.0 COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,1RS3J@1236|Gammaproteobacteria,1XW8U@135623|Vibrionales 135623|Vibrionales F Amidohydrolase family - - - - - - - - - - - - Amidohydro_1 k141_13304_2 1116375.VEJY3_02555 6.69e-218 603.0 COG0715@1|root,COG0715@2|Bacteria,1MW53@1224|Proteobacteria,1RX5F@1236|Gammaproteobacteria,1XW6X@135623|Vibrionales 135623|Vibrionales P NMT1/THI5 like - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1 k141_13304_3 1116375.VEJY3_02550 8.98e-187 520.0 COG1116@1|root,COG1116@2|Bacteria,1MUIM@1224|Proteobacteria,1RRG7@1236|Gammaproteobacteria,1XUTQ@135623|Vibrionales 135623|Vibrionales P ATPases associated with a variety of cellular activities - - - ko:K02049 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - ABC_tran k141_13304_4 1116375.VEJY3_02545 4.44e-159 449.0 COG0600@1|root,COG0600@2|Bacteria,1MVAE@1224|Proteobacteria,1RPEN@1236|Gammaproteobacteria,1XW0I@135623|Vibrionales 135623|Vibrionales P Binding-protein-dependent transport system inner membrane component - - - ko:K02050 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - BPD_transp_1 k141_13304_5 1116375.VEJY3_02540 1.28e-209 580.0 COG3491@1|root,COG3491@2|Bacteria,1MUNT@1224|Proteobacteria,1RPI6@1236|Gammaproteobacteria,1XWUT@135623|Vibrionales 135623|Vibrionales C non-haem dioxygenase in morphine synthesis N-terminal - - - - - - - - - - - - 2OG-FeII_Oxy,DIOX_N k141_292_1 1453501.JELR01000001_gene2888 2.61e-292 815.0 COG4805@1|root,COG4805@2|Bacteria,1R5EP@1224|Proteobacteria,1RRS6@1236|Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - DUF885 k141_292_2 1042377.AFPJ01000020_gene2078 4.56e-74 222.0 COG2154@1|root,COG2154@2|Bacteria,1RH99@1224|Proteobacteria,1S5YX@1236|Gammaproteobacteria,467XF@72275|Alteromonadaceae 1236|Gammaproteobacteria H pterin-4-alpha-carbinolamine dehydratase phhB - 4.2.1.96 ko:K01724 ko00790,map00790 - R04734 RC01208 ko00000,ko00001,ko01000,ko04147 - - - Pterin_4a k141_292_3 305900.GV64_15190 4.51e-18 78.2 COG3813@1|root,COG3813@2|Bacteria,1N712@1224|Proteobacteria,1SHYR@1236|Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria - - - ko:K09984 - - - - ko00000 - - - DUF1272 k141_320_1 935837.JAEK01000020_gene604 4.25e-07 53.9 COG1082@1|root,COG1082@2|Bacteria,1U55B@1239|Firmicutes,4IEWS@91061|Bacilli,1ZN2N@1386|Bacillus 91061|Bacilli G Xylose isomerase domain protein TIM barrel - - - - - - - - - - - - - k141_6283_1 1226994.AMZB01000133_gene4830 2.02e-64 214.0 COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,1RN14@1236|Gammaproteobacteria,1YE0A@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine tilS GO:0002097,GO:0002101,GO:0002136,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016879,GO:0032267,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 6.3.4.19 ko:K04075 - - R09597 RC02633,RC02634 ko00000,ko01000,ko03016 - - - ATP_bind_3,TilS,TilS_C k141_6283_2 42565.FP66_10665 1.5e-40 146.0 COG0477@1|root,COG2814@2|Bacteria,1MVKJ@1224|Proteobacteria,1RMHJ@1236|Gammaproteobacteria,1XN9T@135619|Oceanospirillales 135619|Oceanospirillales EGP Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family - - - ko:K08139 ko04113,map04113 - - - ko00000,ko00001,ko02000 2.A.1.1 - - Sugar_tr k141_34677_1 643648.Slip_2200 3.97e-05 47.8 COG0860@1|root,COG0860@2|Bacteria,1TQ74@1239|Firmicutes,24FT2@186801|Clostridia,42JZM@68298|Syntrophomonadaceae 186801|Clostridia M Ami_3 cwlD - 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - Amidase_3 k141_22796_1 1078085.HMPREF1210_01917 1.42e-14 78.2 COG3266@1|root,COG3266@2|Bacteria,1VMAR@1239|Firmicutes,4HVTT@91061|Bacilli 91061|Bacilli S chitinase - - - - - - - - - - - - - k141_3836_1 218284.CCDN010000001_gene988 0.0 1017.0 COG1404@1|root,COG4412@1|root,COG1404@2|Bacteria,COG4412@2|Bacteria,1TPUY@1239|Firmicutes,4HBDE@91061|Bacilli,1ZDEQ@1386|Bacillus 91061|Bacilli O COG1404 Subtilisin-like serine proteases bpr GO:0005575,GO:0005576 - ko:K13276 - - - - ko00000,ko01000,ko01002,ko03110 - - - CarbopepD_reg_2,CarboxypepD_reg,Inhibitor_I9,Peptidase_M6,Peptidase_S8 k141_10886_1 1121921.KB898707_gene1111 1.27e-68 232.0 COG4773@1|root,COG4773@2|Bacteria,1MW5E@1224|Proteobacteria,1RMBD@1236|Gammaproteobacteria,2PMPF@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria P TonB dependent receptor - - - ko:K16088 - - - - ko00000,ko02000 1.B.14.1.10,1.B.14.1.3,1.B.14.1.8 - - Plug,TonB_dep_Rec k141_13326_2 1279017.AQYJ01000024_gene834 1.24e-53 170.0 COG1534@1|root,COG1534@2|Bacteria,1N8K5@1224|Proteobacteria,1SDIM@1236|Gammaproteobacteria,467SC@72275|Alteromonadaceae 1236|Gammaproteobacteria J RNA-binding protein containing KH domain, possibly ribosomal protein yhbY GO:0000027,GO:0000028,GO:0000966,GO:0000967,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0034470,GO:0034471,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0042274,GO:0043021,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1990275 - ko:K07574 - - - - ko00000,ko03009 - - - CRS1_YhbY k141_13326_3 1279017.AQYJ01000024_gene835 7.11e-132 375.0 COG0293@1|root,COG0293@2|Bacteria,1MW1C@1224|Proteobacteria,1RN5M@1236|Gammaproteobacteria,464RW@72275|Alteromonadaceae 1236|Gammaproteobacteria J Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit ftsJ GO:0000027,GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008650,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022607,GO:0022613,GO:0022618,GO:0031167,GO:0032259,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043414,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.166 ko:K02427 - - - - ko00000,ko01000,ko03009 - - - FtsJ k141_13326_4 1279017.AQYJ01000024_gene836 7.66e-298 823.0 COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,1RME8@1236|Gammaproteobacteria,464T9@72275|Alteromonadaceae 1236|Gammaproteobacteria O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins ftsH GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - ko:K03798 - M00742 - - ko00000,ko00002,ko01000,ko01002,ko03110 - - - AAA,FtsH_ext,Peptidase_M41 k141_19212_2 218284.CCDN010000005_gene3312 3.12e-107 313.0 COG2323@1|root,COG2323@2|Bacteria,1TRWQ@1239|Firmicutes,4H9VA@91061|Bacilli,1ZCPH@1386|Bacillus 91061|Bacilli S membrane - - - - - - - - - - - - DUF1657,DUF421 k141_20363_1 218284.CCDN010000002_gene2076 1.38e-116 345.0 COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,4HAAI@91061|Bacilli,1ZBC5@1386|Bacillus 91061|Bacilli S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family yhdH - - ko:K03308 - - - - ko00000 2.A.22.4,2.A.22.5 - - SNF k141_20363_2 1305836.AXVE01000011_gene957 1.2e-26 105.0 COG0665@1|root,COG0665@2|Bacteria,1TQTF@1239|Firmicutes,4HA0F@91061|Bacilli,26DBU@186818|Planococcaceae 91061|Bacilli E FAD dependent oxidoreductase yurR - 1.4.5.1 ko:K00285 ko00360,map00360 - R01374,R09493 RC00006,RC00025 ko00000,ko00001,ko01000 - - - DAO k141_26447_2 709991.Odosp_0762 1.94e-12 70.5 2CD20@1|root,2Z7SQ@2|Bacteria,4NEQ1@976|Bacteroidetes,2FWPF@200643|Bacteroidia 976|Bacteroidetes - - - - - - - - - - - - - - - k141_12153_1 458233.MCCL_1006 1.54e-22 90.5 COG1970@1|root,COG1970@2|Bacteria,1VA14@1239|Firmicutes,4HKIA@91061|Bacilli,4GZ8E@90964|Staphylococcaceae 91061|Bacilli M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell mscL GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - ko:K03282 - - - - ko00000,ko02000 1.A.22.1 - - MscL k141_12153_2 1294265.JCM21738_3613 1.88e-63 203.0 COG2197@1|root,COG2197@2|Bacteria,1V9BE@1239|Firmicutes,4HJTN@91061|Bacilli,1ZQDI@1386|Bacillus 91061|Bacilli K helix_turn_helix, Lux Regulon - - - - - - - - - - - - GAF,GerE k141_321_2 1347086.CCBA010000031_gene890 4.76e-11 59.3 2E2C2@1|root,32XH4@2|Bacteria,1VDJY@1239|Firmicutes,4HMBA@91061|Bacilli,1ZIXP@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2535) ypmP - - - - - - - - - - - DUF2535 k141_2640_2 497964.CfE428DRAFT_0061 2.08e-77 247.0 COG4447@1|root,COG4447@2|Bacteria 2|Bacteria S cellulose binding hcf136 - - - - - - - - - - - BNR,Sortilin-Vps10 k141_34678_1 1294265.JCM21738_3809 8.49e-116 336.0 29WX8@1|root,30IJ9@2|Bacteria,1UJ4S@1239|Firmicutes,4IT1A@91061|Bacilli,1ZCC6@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_16849_2 1042377.AFPJ01000016_gene137 7.27e-116 344.0 29FM1@1|root,302IP@2|Bacteria,1RHJK@1224|Proteobacteria,1S8M8@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - Ter k141_16849_4 1121921.KB898706_gene2437 8.69e-41 144.0 COG1597@1|root,COG1597@2|Bacteria 2|Bacteria I lipid kinase activity - - - - - - - - - - - - DAGK_cat k141_35844_1 1504672.669785679 1.61e-108 326.0 COG3328@1|root,COG3328@2|Bacteria,1MU4P@1224|Proteobacteria,2VKD6@28216|Betaproteobacteria,4AF3N@80864|Comamonadaceae 28216|Betaproteobacteria L PFAM transposase, mutator type - - - ko:K07493 - - - - ko00000 - - - Transposase_mut k141_37026_1 1294265.JCM21738_908 1.25e-83 248.0 COG0154@1|root,COG0154@2|Bacteria,1TRFI@1239|Firmicutes,4HBZA@91061|Bacilli,1ZCZT@1386|Bacillus 91061|Bacilli J COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases - - 3.5.1.4 ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 - R02540,R03096,R03180,R03909,R05551,R05590 RC00010,RC00100,RC00950,RC01025 ko00000,ko00001,ko01000 - - - Amidase k141_31184_1 1279017.AQYJ01000023_gene3096 1.13e-22 92.8 2EIS4@1|root,33CHF@2|Bacteria,1NI1D@1224|Proteobacteria,1SGX0@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_2641_1 1279017.AQYJ01000029_gene3683 3.9e-58 199.0 COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,1RM95@1236|Gammaproteobacteria,465BW@72275|Alteromonadaceae 1236|Gammaproteobacteria I Acetyl propionyl-CoA carboxylase, alpha subunit mccA - 6.4.1.4,6.4.1.5 ko:K01968,ko:K13777 ko00280,ko00281,ko01100,map00280,map00281,map01100 M00036 R03494,R04138 RC00367,RC00942 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2 k141_6285_1 997296.PB1_00750 3.91e-07 50.8 COG1028@1|root,COG1028@2|Bacteria,1TZY6@1239|Firmicutes,4HEU2@91061|Bacilli,1ZCIS@1386|Bacillus 91061|Bacilli IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) ymfI - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short,adh_short_C2 k141_6285_2 218284.CCDN010000001_gene1861 2.65e-55 172.0 2E5KP@1|root,330BT@2|Bacteria,1VGM7@1239|Firmicutes,4HNNX@91061|Bacilli,1ZHTB@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3243) ymfJ - - - - - - - - - - - DUF3243 k141_18121_1 1121875.KB907546_gene2238 1.3e-79 246.0 COG1409@1|root,COG1409@2|Bacteria,4NFAP@976|Bacteroidetes,1I2DE@117743|Flavobacteriia 976|Bacteroidetes S Calcineurin-like phosphoesterase - - - - - - - - - - - - Metallophos,PA14 k141_323_1 218284.CCDN010000005_gene3337 4.62e-84 254.0 COG4221@1|root,COG4221@2|Bacteria,1TRHF@1239|Firmicutes,4HBXH@91061|Bacilli,1ZQ69@1386|Bacillus 91061|Bacilli S Enoyl-(Acyl carrier protein) reductase - - - - - - - - - - - - adh_short k141_35845_1 926550.CLDAP_33910 1.26e-64 206.0 COG0107@1|root,COG0107@2|Bacteria,2G5Y2@200795|Chloroflexi 200795|Chloroflexi E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit hisF GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - - His_biosynth k141_8544_1 1294265.JCM21738_2562 6.69e-260 721.0 COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,4HARF@91061|Bacilli,1ZC4E@1386|Bacillus 91061|Bacilli E COG0747 ABC-type dipeptide transport system, periplasmic component appA_2 - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 k141_10889_1 1042377.AFPJ01000045_gene2584 7.27e-118 350.0 COG0477@1|root,COG2814@2|Bacteria,1MUZ8@1224|Proteobacteria,1T1NH@1236|Gammaproteobacteria,46DC9@72275|Alteromonadaceae 1236|Gammaproteobacteria EGP Acetyl-coenzyme A transporter 1 ampG GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015672,GO:0015835,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1901264,GO:1902600 - ko:K08218 ko01501,map01501 M00628 - - ko00000,ko00001,ko00002,ko02000 2.A.1.25 - - MFS_1 k141_26448_1 1279017.AQYJ01000029_gene3395 8.14e-15 73.2 COG1075@1|root,COG1075@2|Bacteria,1N2W0@1224|Proteobacteria,1S2JW@1236|Gammaproteobacteria,46749@72275|Alteromonadaceae 1236|Gammaproteobacteria S acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - - - - - - - - - - Abhydrolase_6,DUF676,Hydrolase_4 k141_26448_2 1163408.UU9_03932 1.55e-187 536.0 COG3637@1|root,COG3637@2|Bacteria 2|Bacteria M Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - ko:K12980 - - - - ko00000,ko01005 - - - OMP_b-brl,Surface_Ag_2 k141_37027_1 218284.CCDN010000001_gene1205 5.45e-106 311.0 COG2755@1|root,COG2755@2|Bacteria,1UZYP@1239|Firmicutes,4HDQY@91061|Bacilli,1ZEFB@1386|Bacillus 91061|Bacilli E COG2755 Lysophospholipase L1 and related esterases - - - - - - - - - - - - Lipase_GDSL_2 k141_324_1 1267580.AF6_0102 1.36e-10 57.8 COG1358@1|root,COG1358@2|Bacteria,1VFD8@1239|Firmicutes,4HNXS@91061|Bacilli,21VXJ@150247|Anoxybacillus 91061|Bacilli J Ribosomal protein L7Ae/L30e/S12e/Gadd45 family rplGB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K07590 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L7Ae k141_2642_1 1453501.JELR01000002_gene1441 1.91e-167 479.0 COG0745@1|root,COG0745@2|Bacteria,1R2JU@1224|Proteobacteria 1224|Proteobacteria T cheY-homologous receiver domain - - - - - - - - - - - - Response_reg k141_34680_1 218284.CCDN010000001_gene106 9.67e-117 338.0 COG1752@1|root,COG1752@2|Bacteria,1UUVB@1239|Firmicutes,4HDFQ@91061|Bacilli,1ZBCG@1386|Bacillus 91061|Bacilli S esterase of the alpha-beta hydrolase superfamily ylbK GO:0003674,GO:0003824,GO:0016787 - ko:K07001 - - - - ko00000 - - - Patatin k141_26449_1 1279017.AQYJ01000027_gene1683 4.91e-86 280.0 COG5013@1|root,COG5013@2|Bacteria,1MW9S@1224|Proteobacteria,1RQ27@1236|Gammaproteobacteria,465D5@72275|Alteromonadaceae 1236|Gammaproteobacteria C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family narG GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009898,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0031235,GO:0032991,GO:0042126,GO:0043436,GO:0043546,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0097159,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098803,GO:1901363,GO:1902494,GO:1990204,GO:2001057 1.7.5.1 ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 M00529,M00530,M00804 R00798,R01106,R09497 RC02812 ko00000,ko00001,ko00002,ko01000 5.A.3.1 - iSBO_1134.SBO_1842,iUMN146_1321.UM146_09685 Molybdopterin,Molydop_binding,Nitr_red_alph_N k141_26449_2 1279017.AQYJ01000027_gene1682 7.21e-78 244.0 COG1140@1|root,COG1140@2|Bacteria,1MW9Q@1224|Proteobacteria,1RNMJ@1236|Gammaproteobacteria,46653@72275|Alteromonadaceae 1236|Gammaproteobacteria C Nitrate reductase beta subunit narH GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009898,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0031235,GO:0032991,GO:0033554,GO:0042126,GO:0043436,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204,GO:2001057 1.7.5.1 ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 M00529,M00530,M00804 R00798,R01106,R09497 RC02812 ko00000,ko00001,ko00002,ko01000 5.A.3.1 - iEcE24377_1341.EcE24377A_1376,iEcolC_1368.EcolC_2189 Fer4_11,Nitr_red_bet_C k141_13330_1 218284.CCDN010000002_gene2229 4.81e-92 293.0 COG5000@1|root,COG5002@1|root,COG5000@2|Bacteria,COG5002@2|Bacteria,1VS6X@1239|Firmicutes,4HV7W@91061|Bacilli,1ZS6R@1386|Bacillus 91061|Bacilli T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,dCache_1 k141_35846_1 1453501.JELR01000002_gene1226 5.72e-108 313.0 COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,1RN21@1236|Gammaproteobacteria,467AQ@72275|Alteromonadaceae 1236|Gammaproteobacteria L Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle rsmD GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052913,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.171 ko:K08316 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - Cons_hypoth95 k141_37028_1 1294265.JCM21738_1686 1.39e-106 315.0 COG1226@1|root,COG1226@2|Bacteria,1TT0B@1239|Firmicutes,4HBDX@91061|Bacilli,1ZDQI@1386|Bacillus 91061|Bacilli P Ion channel kch - - ko:K10716 - - - - ko00000,ko02000 1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6 - - Ion_trans_2,TrkA_N k141_6288_1 218284.CCDN010000006_gene3685 3.53e-113 348.0 COG0653@1|root,COG0653@2|Bacteria,1TPEY@1239|Firmicutes,4HA22@91061|Bacilli,1ZAXF@1386|Bacillus 91061|Bacilli U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW k141_4950_2 1453501.JELR01000005_gene1734 4.68e-61 188.0 COG0199@1|root,COG0199@2|Bacteria,1MZDT@1224|Proteobacteria,1S62N@1236|Gammaproteobacteria,467UW@72275|Alteromonadaceae 1236|Gammaproteobacteria J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site rpsN GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02954 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S14 k141_4950_3 498211.CJA_0713 1.36e-69 212.0 COG0096@1|root,COG0096@2|Bacteria,1RDG3@1224|Proteobacteria,1S452@1236|Gammaproteobacteria,1FH6T@10|Cellvibrio 1236|Gammaproteobacteria J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit rpsH GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009894,GO:0009987,GO:0010467,GO:0010468,GO:0010608,GO:0015935,GO:0016043,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031323,GO:0031329,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043487,GO:0043488,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0061013,GO:0065003,GO:0065007,GO:0065008,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903311,GO:1990904 - ko:K02994 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S8 k141_4950_4 1279017.AQYJ01000019_gene1463 1e-105 307.0 COG0097@1|root,COG0097@2|Bacteria,1R9YZ@1224|Proteobacteria,1S1Z1@1236|Gammaproteobacteria,466EY@72275|Alteromonadaceae 1236|Gammaproteobacteria J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center rplF GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02933 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L6 k141_4950_5 1453501.JELR01000005_gene1737 1.84e-65 200.0 COG0256@1|root,COG0256@2|Bacteria,1RGY7@1224|Proteobacteria,1S5V2@1236|Gammaproteobacteria,4679B@72275|Alteromonadaceae 1236|Gammaproteobacteria J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance rplR GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02881 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L18p k141_18123_1 1230341.MJ3_08195 9.07e-156 444.0 COG1063@1|root,COG1063@2|Bacteria,1TPIW@1239|Firmicutes,4HB2G@91061|Bacilli 91061|Bacilli E Dehydrogenase fdh - 1.1.1.1,1.1.1.284 ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 - R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_N_assoc,ADH_zinc_N k141_18378_2 1453501.JELR01000005_gene1569 2.94e-13 70.9 COG1361@1|root,COG3210@1|root,COG1361@2|Bacteria,COG3210@2|Bacteria,1QUXB@1224|Proteobacteria,1T5IP@1236|Gammaproteobacteria 1236|Gammaproteobacteria MU Domain of unknown function (DUF4347) - - - - - - - - - - - - DUF11,DUF4347 k141_11223_1 1379698.RBG1_1C00001G0995 2.34e-18 89.7 COG5617@1|root,COG5617@2|Bacteria,2NS5H@2323|unclassified Bacteria 2|Bacteria E Bacterial membrane protein YfhO - - - - - - - - - - - - YfhO k141_620_2 1042377.AFPJ01000032_gene2812 8.89e-84 267.0 COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,1RN3Z@1236|Gammaproteobacteria,465HK@72275|Alteromonadaceae 1236|Gammaproteobacteria U COG4796 Type II secretory pathway, component HofQ pilQ GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0015976,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 - ko:K02507,ko:K02666 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - AMIN,STN,Secretin,Secretin_N k141_19494_1 218284.CCDN010000006_gene3683 3.04e-106 312.0 COG1284@1|root,COG1284@2|Bacteria,1TR9J@1239|Firmicutes,4H9N6@91061|Bacilli,1ZC5M@1386|Bacillus 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2179) yvjA - - - - - - - - - - - DUF2179,YitT_membrane k141_19494_2 218284.CCDN010000006_gene3682 7.34e-53 167.0 COG2010@1|root,COG2010@2|Bacteria,1VEEP@1239|Firmicutes,4HP6N@91061|Bacilli,1ZITU@1386|Bacillus 91061|Bacilli C COG2010 Cytochrome c, mono- and diheme variants cccB - - ko:K12263,ko:K13300 - - - - ko00000 - - - Cytochrome_CBB3 k141_5265_1 1462527.CCDM010000003_gene4188 3.24e-07 50.1 2DK7F@1|root,308SE@2|Bacteria,1U3WJ@1239|Firmicutes,4IDPA@91061|Bacilli,23MCN@182709|Oceanobacillus 91061|Bacilli S Spo0E like sporulation regulatory protein - - - - - - - - - - - - SpoOE-like k141_8853_1 1131730.BAVI_21713 6.85e-58 187.0 COG0413@1|root,COG0413@2|Bacteria,1TPZA@1239|Firmicutes,4H9S8@91061|Bacilli,1ZAWV@1386|Bacillus 91061|Bacilli H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate panB - 2.1.2.11 ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R01226 RC00022,RC00200 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU22430 Pantoate_transf k141_8853_2 218284.CCDN010000001_gene1139 8.61e-37 132.0 COG0414@1|root,COG0414@2|Bacteria,1TP7A@1239|Firmicutes,4HAIQ@91061|Bacilli,1ZAV5@1386|Bacillus 91061|Bacilli H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate panC GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 M00119 R02473 RC00096,RC00141 ko00000,ko00001,ko00002,ko01000 - - - Pantoate_ligase k141_37244_1 1042377.AFPJ01000019_gene2527 6.29e-170 483.0 COG3387@1|root,COG3387@2|Bacteria,1NB01@1224|Proteobacteria,1RS3W@1236|Gammaproteobacteria,46581@72275|Alteromonadaceae 1236|Gammaproteobacteria G PFAM Glycoside hydrolase 15-related - - - - - - - - - - - - Prenyltrans k141_37244_2 1279017.AQYJ01000026_gene214 5.24e-117 341.0 COG0500@1|root,COG2226@2|Bacteria,1R3QX@1224|Proteobacteria,1RYQ8@1236|Gammaproteobacteria,466WF@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Methionine biosynthesis protein MetW - - - - - - - - - - - - Methyltransf_11,Methyltransf_23 k141_10053_1 42565.FP66_15560 1.33e-122 366.0 COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,1RR14@1236|Gammaproteobacteria,1XIX7@135619|Oceanospirillales 135619|Oceanospirillales I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases prpE - 6.2.1.17 ko:K01908 ko00640,ko01100,map00640,map01100 - R00926,R01354 RC00004,RC00043,RC00070,RC02816 ko00000,ko00001,ko01000,ko01004 - - - ACAS_N,AMP-binding,AMP-binding_C k141_34948_1 1042377.AFPJ01000055_gene965 8.69e-109 329.0 COG2327@1|root,COG2327@2|Bacteria,1MXWP@1224|Proteobacteria,1RRDB@1236|Gammaproteobacteria 1236|Gammaproteobacteria S biosynthesis protein wcaK - - ko:K16710 - - - - ko00000 - - iECSF_1327.ECSF_1934,iSBO_1134.SBO_0872 PS_pyruv_trans k141_17089_1 1279017.AQYJ01000027_gene1572 1.65e-129 383.0 COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,1RMPS@1236|Gammaproteobacteria,4654W@72275|Alteromonadaceae 1236|Gammaproteobacteria G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration nnrD GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 - - - - ko00000,ko01000 - - - Carb_kinase,YjeF_N k141_32434_1 1247963.JPHU01000001_gene1813 2.46e-14 72.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2TS1R@28211|Alphaproteobacteria 28211|Alphaproteobacteria I Belongs to the thiolase family - - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N k141_32434_2 330084.JNYZ01000035_gene9100 6.91e-08 56.6 COG1309@1|root,COG1309@2|Bacteria,2I8DN@201174|Actinobacteria,4E14E@85010|Pseudonocardiales 201174|Actinobacteria K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_C_6,TetR_N k141_11224_1 1120953.AUBH01000002_gene1491 7.96e-09 58.2 COG2252@1|root,COG2252@2|Bacteria,1QU00@1224|Proteobacteria,1T1JI@1236|Gammaproteobacteria,464UK@72275|Alteromonadaceae 1236|Gammaproteobacteria S Xanthine uracil vitamin C permease - - - - - - - - - - - - Xan_ur_permease k141_4104_1 1453501.JELR01000002_gene55 2.74e-267 781.0 COG2911@1|root,COG2911@2|Bacteria,1MUVD@1224|Proteobacteria 1224|Proteobacteria M Protein conserved in bacteria tamB - - ko:K09800 - - - - ko00000,ko02000 - - - TamB k141_4104_3 1279017.AQYJ01000026_gene384 6.04e-108 321.0 COG3228@1|root,COG3228@2|Bacteria,1RAHF@1224|Proteobacteria,1RZQU@1236|Gammaproteobacteria,4674U@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the MtfA family mtfA GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0006508,GO:0006807,GO:0008134,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009889,GO:0010468,GO:0010556,GO:0016787,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031326,GO:0043170,GO:0043433,GO:0044092,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0048519,GO:0050789,GO:0050794,GO:0051090,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0065009,GO:0070011,GO:0071704,GO:0080090,GO:0140096,GO:1901564,GO:1903506,GO:2000112,GO:2001141 - ko:K09933 - - - - ko00000,ko01002 - - - Peptidase_M90 k141_20633_1 1279017.AQYJ01000024_gene939 5.9e-60 189.0 COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,1RSY6@1236|Gammaproteobacteria,466D6@72275|Alteromonadaceae 1236|Gammaproteobacteria P Reversible hydration of carbon dioxide can GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008270,GO:0015976,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914 4.2.1.1 ko:K01673 ko00910,map00910 - R00132,R10092 RC02807 ko00000,ko00001,ko01000 - - iSBO_1134.SBO_0115,iSbBS512_1146.SbBS512_E0119 Pro_CA k141_20633_2 1453501.JELR01000001_gene2989 3.65e-146 429.0 COG0446@1|root,COG1773@1|root,COG0446@2|Bacteria,COG1773@2|Bacteria,1NR3M@1224|Proteobacteria,1RQ07@1236|Gammaproteobacteria,46561@72275|Alteromonadaceae 1236|Gammaproteobacteria C NAD(FAD)-dependent dehydrogenases rubB - 1.18.1.1 ko:K05297 ko00071,map00071 - R02000 - ko00000,ko00001,ko01000 - - - Pyr_redox_2,Rubredoxin k141_2813_2 218284.CCDN010000009_gene4314 1.25e-79 242.0 COG2200@1|root,COG2200@2|Bacteria,1V6YK@1239|Firmicutes,4HIIM@91061|Bacilli,1ZH5W@1386|Bacillus 91061|Bacilli T Putative diguanylate phosphodiesterase - - - - - - - - - - - - EAL k141_31335_1 42565.FP66_10890 4.57e-113 328.0 COG4215@1|root,COG4215@2|Bacteria,1RFA8@1224|Proteobacteria,1S4QE@1236|Gammaproteobacteria,1XINA@135619|Oceanospirillales 135619|Oceanospirillales E Binding-protein-dependent transport system inner membrane component - - - ko:K02029 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 k141_33810_1 1161401.ASJA01000005_gene2418 1.05e-41 154.0 COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,2TSGE@28211|Alphaproteobacteria 28211|Alphaproteobacteria U COG0457 FOG TPR repeat - - - - - - - - - - - - Sulfotransfer_3,TPR_16,TPR_19,TPR_2,TPR_8 k141_621_1 1453501.JELR01000002_gene501 2.85e-83 254.0 COG1716@1|root,COG1716@2|Bacteria,1REM9@1224|Proteobacteria,1S46E@1236|Gammaproteobacteria 1236|Gammaproteobacteria T COG1716 FOG FHA domain - - - - - - - - - - - - FHA k141_18381_1 866895.HBHAL_2192 1.12e-83 254.0 COG1024@1|root,COG1024@2|Bacteria,1TRCQ@1239|Firmicutes,4HDUU@91061|Bacilli,3NEEE@45667|Halobacillus 91061|Bacilli I Enoyl-CoA hydratase/isomerase yhaR - - - - - - - - - - - ECH_1 k141_13712_2 1453501.JELR01000001_gene3055 4.09e-145 410.0 COG0175@1|root,COG0175@2|Bacteria,1MXUR@1224|Proteobacteria,1RNC5@1236|Gammaproteobacteria,46452@72275|Alteromonadaceae 1236|Gammaproteobacteria EH Belongs to the PAPS reductase family. CysH subfamily cysH - 1.8.4.10,1.8.4.8 ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00176 R02021 RC00007,RC02862 ko00000,ko00001,ko00002,ko01000 - - - PAPS_reduct k141_13712_4 1279017.AQYJ01000027_gene1797 0.0 1447.0 COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,1RNB2@1236|Gammaproteobacteria,464Q3@72275|Alteromonadaceae 1236|Gammaproteobacteria L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrB GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009330,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0032991,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:0140097,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 5.99.1.3 ko:K02470 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim k141_13712_5 1279017.AQYJ01000027_gene1798 5.52e-170 485.0 COG1195@1|root,COG1195@2|Bacteria,1MX8N@1224|Proteobacteria,1RN5P@1236|Gammaproteobacteria,466CC@72275|Alteromonadaceae 1236|Gammaproteobacteria L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP recF GO:0000731,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0018130,GO:0019438,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - ko:K03629 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - SMC_N k141_34974_1 1232683.ADIMK_2598 5.97e-97 294.0 28H52@1|root,2Z7HQ@2|Bacteria,1MXTF@1224|Proteobacteria,1RN8H@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF1329) - - - - - - - - - - - - DUF1329 k141_34974_2 1208321.D104_10325 9.08e-146 419.0 COG1073@1|root,COG1073@2|Bacteria,1MXJ3@1224|Proteobacteria,1RRZK@1236|Gammaproteobacteria 1236|Gammaproteobacteria S hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - - - - - - - - - - Abhydrolase_6,DUF1100,Peptidase_S9 k141_640_1 1042377.AFPJ01000050_gene1321 3.18e-32 116.0 COG2606@1|root,COG2606@2|Bacteria,1N10Y@1224|Proteobacteria,1SAQE@1236|Gammaproteobacteria 1236|Gammaproteobacteria S YbaK prolyl-tRNA synthetase associated - - - ko:K19055 - - - - ko00000,ko01000,ko03016 - - - tRNA_edit k141_24202_1 218284.CCDN010000001_gene1201 3.13e-18 77.0 2E2C2@1|root,32XH4@2|Bacteria,1VDJY@1239|Firmicutes,4HMBA@91061|Bacilli,1ZIXP@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2535) ypmP - - - - - - - - - - - DUF2535 k141_24202_2 218284.CCDN010000001_gene1200 3.9e-150 422.0 COG2135@1|root,COG2135@2|Bacteria,1TRRV@1239|Firmicutes,4HDUN@91061|Bacilli,1ZCQB@1386|Bacillus 91061|Bacilli S Belongs to the SOS response-associated peptidase family yoqW - - - - - - - - - - - SRAP k141_32450_1 218284.CCDN010000001_gene1781 6.59e-47 154.0 COG1994@1|root,COG1994@2|Bacteria,1V8QC@1239|Firmicutes,4HK02@91061|Bacilli,1ZQQW@1386|Bacillus 91061|Bacilli S Peptidase M50 ywmF - - - - - - - - - - - Peptidase_M50 k141_32450_2 997296.PB1_00545 2.31e-19 81.6 291YW@1|root,2ZPID@2|Bacteria,1V3V6@1239|Firmicutes,4HGYJ@91061|Bacilli,1ZG6E@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2621) yneK - - - - - - - - - - - DUF2621 k141_5304_1 218284.CCDN010000007_gene3999 1.08e-190 539.0 COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,4HAMZ@91061|Bacilli,1ZB13@1386|Bacillus 91061|Bacilli C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit atpA - 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - iSB619.SA_RS10975 ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N k141_5304_2 218284.CCDN010000007_gene3998 2.67e-53 171.0 COG0712@1|root,COG0712@2|Bacteria,1VAG3@1239|Firmicutes,4HKFW@91061|Bacilli,1ZG65@1386|Bacillus 91061|Bacilli C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpH - - ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - OSCP k141_36052_1 29495.EA26_08475 2.58e-32 127.0 COG3291@1|root,COG3591@1|root,COG3291@2|Bacteria,COG3591@2|Bacteria,1QDPR@1224|Proteobacteria,1RN6D@1236|Gammaproteobacteria,1XWET@135623|Vibrionales 135623|Vibrionales E Trypsin-like peptidase domain - - - - - - - - - - - - PPC,Trypsin_2 k141_25525_1 981383.AEWH01000010_gene3820 1.21e-35 125.0 COG3677@1|root,COG3677@2|Bacteria,1V8R5@1239|Firmicutes,4HJMG@91061|Bacilli 91061|Bacilli L Transposase yqaQ - - - - - - - - - - - GerE,HTH_28 k141_1611_1 234267.Acid_5192 6.03e-186 529.0 COG3391@1|root,COG3391@2|Bacteria,3Y7BN@57723|Acidobacteria 57723|Acidobacteria S 56kDa selenium binding protein (SBP56) - - - ko:K17285 - - - - ko00000,ko04147 - - - SBP56 k141_1611_2 1125971.ASJB01000064_gene6580 3.67e-26 107.0 COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria,4DYZC@85010|Pseudonocardiales 201174|Actinobacteria K Sigma-70 region 2 - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_31352_1 218284.CCDN010000004_gene3046 1.73e-227 632.0 COG1301@1|root,COG1301@2|Bacteria,1TP4N@1239|Firmicutes,4HAUP@91061|Bacilli,1ZBYS@1386|Bacillus 91061|Bacilli C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family dctP - - - - - - - - - - - SDF k141_13713_1 1294265.JCM21738_2828 8.3e-131 377.0 COG1018@1|root,COG1018@2|Bacteria,1VH7V@1239|Firmicutes,4HUIM@91061|Bacilli,1ZDKF@1386|Bacillus 91061|Bacilli C 2Fe-2S iron-sulfur cluster binding domain - - 1.14.13.238 ko:K22343 - - - - ko00000,ko01000 - - - FAD_binding_6,Fer2,NAD_binding_1 k141_4118_1 580331.Thit_0781 2.18e-78 254.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,42F9E@68295|Thermoanaerobacterales 186801|Clostridia V ABC transporter, transmembrane region - - - ko:K18889 ko02010,map02010 M00707 - - ko00000,ko00001,ko00002,ko02000 3.A.1.106.13,3.A.1.106.5 - - ABC_membrane,ABC_tran k141_11251_4 674977.VMC_38520 1.33e-91 268.0 2AW2H@1|root,31MX9@2|Bacteria,1QJT1@1224|Proteobacteria,1THUA@1236|Gammaproteobacteria,1XXJU@135623|Vibrionales 135623|Vibrionales S Phage protein - - - - - - - - - - - - DUF3653 k141_6481_1 883081.HMPREF9698_01608 6.95e-23 95.5 2CIG6@1|root,3042M@2|Bacteria,1V4MS@1239|Firmicutes,4HHBB@91061|Bacilli,27HFT@186828|Carnobacteriaceae 91061|Bacilli - - - - - - - - - - - - - - Phage_capsid k141_6481_2 1033740.CAEW01000026_gene530 3.19e-27 105.0 2DPCU@1|root,331IS@2|Bacteria,1VFIK@1239|Firmicutes,4HPAM@91061|Bacilli,26HVB@186818|Planococcaceae 91061|Bacilli S Phage minor structural protein GP20 - - - - - - - - - - - - Phage_GP20 k141_10087_1 218284.CCDN010000001_gene11 4.8e-104 331.0 2C5DW@1|root,2Z7RX@2|Bacteria,1TT0I@1239|Firmicutes,4HDMQ@91061|Bacilli,1ZQMF@1386|Bacillus 91061|Bacilli - - ylqG - - - - - - - - - - - - k141_14682_2 279238.Saro_1562 1.86e-28 112.0 COG1024@1|root,COG1024@2|Bacteria,1PSRK@1224|Proteobacteria,2U22I@28211|Alphaproteobacteria,2K67F@204457|Sphingomonadales 204457|Sphingomonadales I Enoyl-CoA hydratase/isomerase - - - - - - - - - - - - ECH_1 k141_32451_1 218284.CCDN010000005_gene3188 1.68e-39 139.0 COG4585@1|root,COG4585@2|Bacteria,1TPDG@1239|Firmicutes,4HC7E@91061|Bacilli,1ZB48@1386|Bacillus 91061|Bacilli T Histidine kinase - - 2.7.13.3 ko:K11617 ko02020,map02020 M00481,M00754 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA_3 k141_19525_1 665959.HMPREF1013_04481 3.79e-92 275.0 COG1131@1|root,COG1131@2|Bacteria,1TQIH@1239|Firmicutes,4HCT1@91061|Bacilli,1ZCRH@1386|Bacillus 91061|Bacilli V ABC transporter CcmA5 - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_23186_1 1298598.JCM21714_1942 3.14e-57 181.0 2E9V0@1|root,3340V@2|Bacteria,1V6HR@1239|Firmicutes,4HIXZ@91061|Bacilli 91061|Bacilli S carotenoid biosynthetic process - - - ko:K10212 ko00906,map00906 - R07656 RC00041 ko00000,ko00001,ko01000 - - - - k141_23186_2 218284.CCDN010000002_gene2510 2.81e-315 863.0 COG1233@1|root,COG1233@2|Bacteria,1TS4A@1239|Firmicutes,4HB9J@91061|Bacilli,1ZCTK@1386|Bacillus 91061|Bacilli Q COG1233 Phytoene dehydrogenase and related proteins crtN - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 ko:K10027 ko00906,ko01100,ko01110,map00906,map01100,map01110 - R04787,R04798,R04800,R09691,R09692 RC01214,RC02088,RC02605 ko00000,ko00001,ko01000 - - - Amino_oxidase,NAD_binding_8 k141_15911_1 218284.CCDN010000001_gene631 1.11e-86 262.0 COG1994@1|root,COG1994@2|Bacteria,1V72P@1239|Firmicutes,4HJFP@91061|Bacilli,1ZQIE@1386|Bacillus 91061|Bacilli S Peptidase family M50 spoIVFB - - ko:K06402 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M50,Peptidase_M50B k141_34977_1 1279017.AQYJ01000026_gene55 2.04e-212 610.0 COG1049@1|root,COG1049@2|Bacteria,1MVCR@1224|Proteobacteria,1RNMC@1236|Gammaproteobacteria,46445@72275|Alteromonadaceae 1236|Gammaproteobacteria C Belongs to the aconitase IPM isomerase family acnB - 4.2.1.3,4.2.1.99 ko:K01682 ko00020,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173 R01324,R01325,R01900,R04425 RC00497,RC00498,RC00618,RC01153 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_2_N,Aconitase_B_N k141_11253_1 218284.CCDN010000001_gene1662 1.22e-62 197.0 COG0454@1|root,COG0456@2|Bacteria,1TQ7M@1239|Firmicutes,4HGSS@91061|Bacilli,1ZGQ3@1386|Bacillus 91061|Bacilli K Acetyltransferase (GNAT) family - - - - - - - - - - - - Acetyltransf_1 k141_24205_1 1294265.JCM21738_675 2.63e-125 365.0 COG0065@1|root,COG0065@2|Bacteria,1TPE5@1239|Firmicutes,4HAWA@91061|Bacilli,1ZCF1@1386|Bacillus 91061|Bacilli E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate leuC - 4.2.1.33,4.2.1.35 ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170 RC00497,RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS10700 Aconitase k141_8883_1 1279017.AQYJ01000024_gene1192 2.01e-191 536.0 COG0082@1|root,COG0082@2|Bacteria,1MU98@1224|Proteobacteria,1RMQS@1236|Gammaproteobacteria,46517@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system aroC GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01714 RC00586 ko00000,ko00001,ko00002,ko01000 - - iE2348C_1286.E2348C_2469,iEC55989_1330.EC55989_2573,iECO103_1326.ECO103_2794,iECO111_1330.ECO111_3077,iECO26_1355.ECO26_3317,iECSE_1348.ECSE_2638,iECW_1372.ECW_m2518,iEKO11_1354.EKO11_1436,iSSON_1240.SSON_2387,iUMNK88_1353.UMNK88_2882,iWFL_1372.ECW_m2518 Chorismate_synt k141_10090_1 1246484.D479_20093 4.94e-40 137.0 COG0494@1|root,COG0494@2|Bacteria,1V6SF@1239|Firmicutes,4HG46@91061|Bacilli,3NDGS@45667|Halobacillus 91061|Bacilli L NUDIX domain XK27_06885 - - - - - - - - - - - NUDIX k141_4120_1 218284.CCDN010000001_gene1700 1.81e-100 303.0 COG0162@1|root,COG0162@2|Bacteria,1TPGN@1239|Firmicutes,4H9YV@91061|Bacilli,1ZBY9@1386|Bacillus 91061|Bacilli J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) tyrS GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - S4,tRNA-synt_1b k141_11254_1 218284.CCDN010000001_gene1167 3.52e-134 394.0 COG0843@1|root,COG0843@2|Bacteria,1TPZC@1239|Firmicutes,4HAHT@91061|Bacilli,1ZC76@1386|Bacillus 91061|Bacilli C COG0843 Heme copper-type cytochrome quinol oxidases, subunit 1 cbaA - 1.9.3.1 ko:K02274 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6 - - COX1 k141_24206_1 1453501.JELR01000002_gene1414 4.43e-116 339.0 COG1878@1|root,COG1878@2|Bacteria,1MWWB@1224|Proteobacteria,1RS83@1236|Gammaproteobacteria,46DJ7@72275|Alteromonadaceae 1236|Gammaproteobacteria S Putative cyclase - - - - - - - - - - - - Cyclase k141_17109_2 1279017.AQYJ01000028_gene2504 5.57e-214 597.0 COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,1RNHY@1236|Gammaproteobacteria,464JW@72275|Alteromonadaceae 1236|Gammaproteobacteria O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins dnaJ GO:0006457,GO:0008150,GO:0009987 - ko:K03686 - - - - ko00000,ko03029,ko03110 - - - DnaJ,DnaJ_C,DnaJ_CXXCXGXG k141_14684_1 1042377.AFPJ01000020_gene2086 2.13e-25 101.0 COG0668@1|root,COG0668@2|Bacteria,1PMY3@1224|Proteobacteria,1SZY7@1236|Gammaproteobacteria,4672N@72275|Alteromonadaceae 1236|Gammaproteobacteria M Mechanosensitive ion channel - - - - - - - - - - - - MS_channel k141_14684_2 1279017.AQYJ01000025_gene528 2.02e-44 149.0 COG1182@1|root,COG1182@2|Bacteria,1P59R@1224|Proteobacteria,1S337@1236|Gammaproteobacteria,466Y8@72275|Alteromonadaceae 1236|Gammaproteobacteria I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity azoR - - ko:K01118 - - - - ko00000,ko01000 - - - Flavodoxin_2 k141_21887_1 1279017.AQYJ01000026_gene66 1.87e-288 807.0 COG0457@1|root,COG0457@2|Bacteria,1MXSS@1224|Proteobacteria,1S157@1236|Gammaproteobacteria,46CPY@72275|Alteromonadaceae 1236|Gammaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16 k141_21887_2 1279017.AQYJ01000026_gene65 3e-146 449.0 COG4105@1|root,COG4105@2|Bacteria,1QVQ9@1224|Proteobacteria,1RSIG@1236|Gammaproteobacteria,46DC5@72275|Alteromonadaceae 1236|Gammaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16,TPR_6 k141_34980_1 243233.MCA3085 4.39e-51 172.0 COG2304@1|root,COG2304@2|Bacteria,1MXQ7@1224|Proteobacteria,1RMDX@1236|Gammaproteobacteria,1XDQK@135618|Methylococcales 135618|Methylococcales S von Willebrand factor, type A - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - VWA k141_6483_1 1236541.BALL01000026_gene3027 2.28e-94 293.0 2EXJW@1|root,33QVY@2|Bacteria,1QSMJ@1224|Proteobacteria,1SK5H@1236|Gammaproteobacteria,2QA2U@267890|Shewanellaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_25526_1 1279017.AQYJ01000022_gene2689 0.0 1398.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,46425@72275|Alteromonadaceae 1236|Gammaproteobacteria V Efflux pump mexF - - ko:K18138,ko:K18299,ko:K19585 ko01501,ko01503,map01501,map01503 M00641,M00647,M00699,M00718,M00767 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2,2.A.6.2.16,2.A.6.2.47 - - ACR_tran k141_10092_1 218284.CCDN010000001_gene989 5.47e-53 184.0 COG1884@1|root,COG1884@2|Bacteria,1TSVA@1239|Firmicutes,4HDE1@91061|Bacilli,1ZAVR@1386|Bacillus 91061|Bacilli I COG1884 Methylmalonyl-CoA mutase, N-terminal domain subunit mutA - 5.4.99.2 ko:K01847 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00373,M00376,M00741 R00833 RC00395 ko00000,ko00001,ko00002,ko01000 - - - MM_CoA_mutase k141_27680_2 1279017.AQYJ01000029_gene3581 1.36e-107 310.0 COG1522@1|root,COG1522@2|Bacteria,1MX7R@1224|Proteobacteria,1S4N9@1236|Gammaproteobacteria,46CRI@72275|Alteromonadaceae 1236|Gammaproteobacteria K AsnC-type helix-turn-helix domain bkdR - - ko:K03719 - - - - ko00000,ko03000,ko03036 - - - AsnC_trans_reg,HTH_24 k141_27680_3 1439940.BAY1663_01427 6.76e-28 102.0 2DNYP@1|root,32ZTI@2|Bacteria,1N747@1224|Proteobacteria,1SCCQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF2905) - - - - - - - - - - - - DUF2905 k141_20658_2 1279017.AQYJ01000019_gene1457 3.32e-50 159.0 COG0186@1|root,COG0186@2|Bacteria,1MZIK@1224|Proteobacteria,1S8SS@1236|Gammaproteobacteria,467RN@72275|Alteromonadaceae 1236|Gammaproteobacteria J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA rpsQ GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046677,GO:0050896,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02961 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S17 k141_20658_3 1453501.JELR01000005_gene1729 4.26e-31 109.0 COG0255@1|root,COG0255@2|Bacteria,1N6PR@1224|Proteobacteria,1SCBN@1236|Gammaproteobacteria,468D6@72275|Alteromonadaceae 1236|Gammaproteobacteria J Belongs to the universal ribosomal protein uL29 family rpmC GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02904 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L29 k141_20658_4 1042377.AFPJ01000055_gene999 2e-88 260.0 COG0197@1|root,COG0197@2|Bacteria,1RA0Z@1224|Proteobacteria,1S201@1236|Gammaproteobacteria,466H8@72275|Alteromonadaceae 1236|Gammaproteobacteria J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs rplP GO:0000027,GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02878 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L16 k141_20658_5 1279017.AQYJ01000019_gene1454 8.94e-149 420.0 COG0092@1|root,COG0092@2|Bacteria,1MUAI@1224|Proteobacteria,1RN0P@1236|Gammaproteobacteria,46670@72275|Alteromonadaceae 1236|Gammaproteobacteria J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation rpsC GO:0000028,GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02982 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KH_2,Ribosomal_S3_C k141_20658_7 498211.CJA_0703 6.73e-59 182.0 COG0185@1|root,COG0185@2|Bacteria,1RGYX@1224|Proteobacteria,1S5VT@1236|Gammaproteobacteria,1FHNZ@10|Cellvibrio 1236|Gammaproteobacteria J Ribosomal protein S19 rpsS GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02965 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S19 k141_34981_1 1294265.JCM21738_2457 2.25e-58 185.0 2CDA7@1|root,333AV@2|Bacteria,1VHFF@1239|Firmicutes,4HRPJ@91061|Bacilli,1ZG31@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_34981_2 545693.BMQ_1976 0.000128 40.8 29SAB@1|root,30DEV@2|Bacteria,1UB7S@1239|Firmicutes,4IMKI@91061|Bacilli,1ZKCF@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_1613_1 218284.CCDN010000002_gene2056 8e-289 800.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,1ZBIW@1386|Bacillus 91061|Bacilli V COG1132 ABC-type multidrug transport system, ATPase and permease components yfiC3 - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran k141_17110_2 485916.Dtox_4336 2.58e-44 145.0 2C82G@1|root,32RK9@2|Bacteria,1VZ8X@1239|Firmicutes 1239|Firmicutes S Protein of unknown function (DUF4242) - - - - - - - - - - - - DUF4242 k141_23188_1 1408303.JNJJ01000103_gene2429 7.23e-102 306.0 COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,4H9RY@91061|Bacilli,1ZE2W@1386|Bacillus 91061|Bacilli S MviN-like protein - - - - - - - - - - - - Polysacc_synt,Polysacc_synt_C k141_18424_3 1116375.VEJY3_14295 5.29e-238 655.0 COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,1RNDC@1236|Gammaproteobacteria,1XUUG@135623|Vibrionales 135623|Vibrionales J Tryptophanyl-tRNA synthetase trpS GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1b k141_34034_1 1453501.JELR01000002_gene569 6.65e-98 292.0 COG3217@1|root,COG3217@2|Bacteria,1MXN2@1224|Proteobacteria,1RMN7@1236|Gammaproteobacteria,4676N@72275|Alteromonadaceae 1236|Gammaproteobacteria C Fe-S protein ycbX GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009636,GO:0009987,GO:0019748,GO:0042221,GO:0044237,GO:0044248,GO:0050896,GO:0098754 - ko:K07140 - - - - ko00000 - - - FAD_binding_6,Fer2,MOSC,MOSC_N,NAD_binding_1 k141_34034_2 1453501.JELR01000002_gene565 1.04e-25 107.0 COG2199@1|root,COG3706@2|Bacteria,1MWHH@1224|Proteobacteria,1RRU7@1236|Gammaproteobacteria,465TD@72275|Alteromonadaceae 1236|Gammaproteobacteria T 7TMR-DISM extracellular 2 - - - - - - - - - - - - 7TMR-DISMED2,7TMR-DISM_7TM,GGDEF k141_22101_1 1279017.AQYJ01000028_gene2511 6.91e-05 44.3 COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,1RPIU@1236|Gammaproteobacteria,46439@72275|Alteromonadaceae 1236|Gammaproteobacteria F COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ) carB GO:0000050,GO:0000166,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016053,GO:0016597,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b0033,iBWG_1329.BWG_0031,iECDH10B_1368.ECDH10B_0034,iECDH1ME8569_1439.ECDH1ME8569_0031,iECUMN_1333.ECUMN_0034,iEcDH1_1363.EcDH1_3566,iJN746.PP_4723,iJO1366.b0033,iJR904.b0033,iPC815.YPO0482,iY75_1357.Y75_RS00170,iYL1228.KPN_00041 CPSase_L_D2,CPSase_L_D3,MGS k141_22101_3 1042377.AFPJ01000051_gene45 3.83e-06 55.8 2DRE1@1|root,33BC9@2|Bacteria,1NGYJ@1224|Proteobacteria 1224|Proteobacteria S PFAM Curlin associated repeat - - - - - - - - - - - - Curlin_rpt k141_14905_1 218284.CCDN010000002_gene2107 1.06e-99 297.0 COG0022@1|root,COG0022@2|Bacteria,1TP3J@1239|Firmicutes,4HAEB@91061|Bacilli,1ZBM7@1386|Bacillus 91061|Bacilli C Transketolase, C-terminal domain pdhB2 - 1.2.4.1 ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C k141_1798_1 1116375.VEJY3_20346 0.0 1425.0 COG0204@1|root,COG0318@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1T1II@1236|Gammaproteobacteria,1XW5B@135623|Vibrionales 135623|Vibrionales IQ AMP-binding enzyme - - - - - - - - - - - - AMP-binding,Acyltransferase,PP-binding k141_1798_2 1116375.VEJY3_20341 0.0 984.0 COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria,1MVU6@1224|Proteobacteria,1RNY5@1236|Gammaproteobacteria,1XT71@135623|Vibrionales 135623|Vibrionales C Electron transfer flavoprotein-ubiquinone oxidoreductase etfD - 1.5.5.1 ko:K00311 - - - - ko00000,ko01000 - - - ETF_QO,FAD_binding_2,NAD_binding_8 k141_1798_3 1116375.VEJY3_20336 5.39e-90 273.0 COG0508@1|root,COG0508@2|Bacteria,1MVDC@1224|Proteobacteria,1RQ9Y@1236|Gammaproteobacteria,1XV98@135623|Vibrionales 135623|Vibrionales C COG0508 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes pdhC - 2.3.1.12 ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding k141_9142_1 218284.CCDN010000001_gene1570 4.47e-61 204.0 COG1960@1|root,COG1960@2|Bacteria,1TQC8@1239|Firmicutes,4HC6Y@91061|Bacilli,1ZCXT@1386|Bacillus 91061|Bacilli I Acyl-CoA dehydrogenase, middle domain - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M k141_29224_1 1132442.KB889752_gene2729 1.4e-120 358.0 COG1524@1|root,COG1524@2|Bacteria,1UY6W@1239|Firmicutes,4HDR4@91061|Bacilli,1ZDAM@1386|Bacillus 91061|Bacilli S Type I phosphodiesterase / nucleotide pyrophosphatase - - - - - - - - - - - - Phosphodiest k141_29224_2 218284.CCDN010000001_gene569 1.49e-08 55.1 COG1215@1|root,COG1215@2|Bacteria,1TPBB@1239|Firmicutes,4HBVS@91061|Bacilli,1ZPUV@1386|Bacillus 91061|Bacilli M Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 k141_37454_1 218284.CCDN010000001_gene1826 1.01e-105 306.0 2BYGR@1|root,31NH1@2|Bacteria,1V9DE@1239|Firmicutes,4IR5R@91061|Bacilli,1ZRRX@1386|Bacillus 91061|Bacilli S Outer spore coat protein E (CotE) - - - ko:K06328 - - - - ko00000 - - - CotE k141_24527_1 458233.MCCL_0946 1.24e-30 120.0 COG5377@1|root,COG5377@2|Bacteria,1TS2Y@1239|Firmicutes,4HAFK@91061|Bacilli,4GYBU@90964|Staphylococcaceae 91061|Bacilli L YqaJ-like viral recombinase domain yqaJ - - - - - - - - - - - YqaJ k141_29225_1 1294265.JCM21738_4750 5.15e-98 287.0 COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,4HC17@91061|Bacilli,1ZCZ4@1386|Bacillus 91061|Bacilli K Belongs to the sigma-70 factor family. ECF subfamily sigW - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_6736_1 1294265.JCM21738_1919 1.55e-102 300.0 COG0741@1|root,COG0741@2|Bacteria,1V6DD@1239|Firmicutes,4HIWA@91061|Bacilli,1ZH33@1386|Bacillus 91061|Bacilli M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) yjbJ - - - - - - - - - - - SLT k141_6736_2 1294265.JCM21738_1918 2.17e-78 236.0 COG4116@1|root,COG4116@2|Bacteria,1VA56@1239|Firmicutes,4HMNE@91061|Bacilli,1ZH0U@1386|Bacillus 91061|Bacilli S protein conserved in bacteria yjbK - - - - - - - - - - - CYTH k141_11566_2 1169144.KB910939_gene2822 1.28e-71 223.0 COG0596@1|root,COG0596@2|Bacteria,1TR6D@1239|Firmicutes,4HFA0@91061|Bacilli,1ZFYE@1386|Bacillus 91061|Bacilli S alpha/beta hydrolase fold - - - - - - - - - - - - Abhydrolase_1 k141_24528_1 218284.CCDN010000001_gene1217 3.83e-105 313.0 COG0624@1|root,COG0624@2|Bacteria,1TQS9@1239|Firmicutes,4HDHW@91061|Bacilli,1ZBDC@1386|Bacillus 91061|Bacilli E Acetylornithine deacetylase yodQ - 3.5.1.16,3.5.1.18 ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R00669,R02734,R09107 RC00064,RC00090,RC00300 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20,Peptidase_M28 k141_18726_1 1340434.AXVA01000020_gene1378 4.15e-37 138.0 COG0601@1|root,COG0601@2|Bacteria,1TRW4@1239|Firmicutes,4HEGZ@91061|Bacilli,1ZH5U@1386|Bacillus 91061|Bacilli EP Binding-protein-dependent transport system inner membrane component - - - - - - - - - - - - BPD_transp_1 k141_14907_1 218284.CCDN010000001_gene131 3.63e-111 325.0 COG1612@1|root,COG1612@2|Bacteria,1TR4W@1239|Firmicutes,4HC12@91061|Bacilli,1ZC0K@1386|Bacillus 91061|Bacilli O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group ctaA GO:0000003,GO:0003674,GO:0003824,GO:0008150,GO:0009987,GO:0016043,GO:0017004,GO:0019954,GO:0022607,GO:0030436,GO:0032502,GO:0034622,GO:0043933,GO:0043934,GO:0044085,GO:0065003,GO:0071840 - ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 M00154 R07412 RC00769 ko00000,ko00001,ko00002,ko03029 3.D.4.4 - iSB619.SA_RS05460,iYO844.BSU14870 COX15-CtaA k141_14034_2 218284.CCDN010000005_gene3258 1.51e-178 500.0 COG1284@1|root,COG1284@2|Bacteria,1TRBT@1239|Firmicutes,4HBPR@91061|Bacilli,1ZDFA@1386|Bacillus 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2179) yitT - - - - - - - - - - - DUF2179,YitT_membrane k141_14034_5 634956.Geoth_3098 1.11e-14 67.4 2EESV@1|root,338KD@2|Bacteria,1VFET@1239|Firmicutes,4HP8V@91061|Bacilli,1WH12@129337|Geobacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_14034_6 1220589.CD32_14155 0.000696 41.6 COG0561@1|root,COG0561@2|Bacteria,1TREF@1239|Firmicutes,4H9Y9@91061|Bacilli,3IWG4@400634|Lysinibacillus 91061|Bacilli S Phosphatase yitU - 3.1.3.104 ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R07280 RC00017 ko00000,ko00001,ko00002,ko01000 - - - Hydrolase_3 k141_27161_2 317025.Tcr_1855 2.57e-55 181.0 COG1230@1|root,COG1230@2|Bacteria,1MUSS@1224|Proteobacteria,1RQ3M@1236|Gammaproteobacteria,460YS@72273|Thiotrichales 72273|Thiotrichales P Cation efflux family - - - - - - - - - - - - Cation_efflux k141_27161_3 557598.LHK_01865 1.95e-15 73.9 COG0599@1|root,COG0599@2|Bacteria,1MZ80@1224|Proteobacteria,2WG6P@28216|Betaproteobacteria,2KU3U@206351|Neisseriales 206351|Neisseriales O Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - - - - - - - - - - CMD k141_11567_1 240302.BN982_02542 4.55e-70 232.0 COG3711@1|root,COG3711@2|Bacteria,1TQT1@1239|Firmicutes,4HABH@91061|Bacilli,3NEA7@45667|Halobacillus 91061|Bacilli K Mga helix-turn-helix domain mtlR - - ko:K03483 - - - - ko00000,ko03000 - - - HTH_11,Mga,PRD,PTS_EIIA_2,PTS_IIB k141_34035_1 218284.CCDN010000004_gene3151 2.09e-130 382.0 COG0189@1|root,COG0189@2|Bacteria,1TSWS@1239|Firmicutes,4HCJA@91061|Bacilli,1ZAR6@1386|Bacillus 91061|Bacilli HJ YheC/D like ATP-grasp yheD GO:0005575,GO:0005623,GO:0042601,GO:0042763,GO:0044464 - - - - - - - - - - ATPgrasp_YheCD k141_18727_1 1453501.JELR01000002_gene1180 5.46e-99 293.0 2A18R@1|root,32DBY@2|Bacteria,1RKWD@1224|Proteobacteria,1S7XE@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Putative general bacterial porin - - - - - - - - - - - - Porin_7 k141_24529_1 1294265.JCM21738_142 3.66e-113 333.0 COG0438@1|root,COG0438@2|Bacteria,1TPS8@1239|Firmicutes,4HA43@91061|Bacilli,1ZASJ@1386|Bacillus 91061|Bacilli M N-acetyl-alpha-D-glucosaminyl L-malate synthase bshA - - ko:K00754 - - - - ko00000,ko01000 - GT4 - Glyco_transf_4,Glycos_transf_1 k141_1800_2 218284.CCDN010000001_gene1207 5.33e-15 72.8 COG1404@1|root,COG1404@2|Bacteria,1V3SC@1239|Firmicutes,4HGZF@91061|Bacilli,1ZGVY@1386|Bacillus 91061|Bacilli O Domain of unknown function (DUF4397) - - - - - - - - - - - - DUF4397 k141_32699_2 218284.CCDN010000001_gene719 3.1e-125 362.0 COG4976@1|root,COG4976@2|Bacteria,1UHZM@1239|Firmicutes,4ISBD@91061|Bacilli,1ZS4Q@1386|Bacillus 91061|Bacilli S Methyltransferase domain - - - - - - - - - - - - Methyltransf_25 k141_29226_1 1117379.BABA_03939 4.45e-68 221.0 COG3243@1|root,COG3243@2|Bacteria,1V0SA@1239|Firmicutes,4HCRB@91061|Bacilli,1ZAX8@1386|Bacillus 91061|Bacilli I Poly(R)-hydroxyalkanoic acid synthase, class III, PhaC subunit phaC - - ko:K03821 ko00650,map00650 - R04254 RC00004 ko00000,ko00001,ko01000 - - - Abhydrolase_1 k141_3008_1 679199.HMPREF9332_01455 1.07e-11 67.4 COG4485@1|root,COG4485@2|Bacteria,4NEE5@976|Bacteroidetes,2FMKE@200643|Bacteroidia,1WD10@1283313|Alloprevotella 976|Bacteroidetes S Bacterial membrane protein YfhO - - - - - - - - - - - - YfhO k141_7792_2 1382358.JHVN01000001_gene1108 2.19e-63 204.0 COG2103@1|root,COG2103@2|Bacteria,1TPSF@1239|Firmicutes,4HBWP@91061|Bacilli 91061|Bacilli G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate murQ - 4.2.1.126 ko:K07106 ko00520,ko01100,map00520,map01100 - R08555 RC00397,RC00746 ko00000,ko00001,ko01000 - - - SIS,SIS_2 k141_9145_1 1453501.JELR01000001_gene2482 2.12e-21 87.0 2E600@1|root,330PC@2|Bacteria,1N9V9@1224|Proteobacteria,1SD3Y@1236|Gammaproteobacteria,468XD@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_848_1 1042377.AFPJ01000028_gene2221 2.1e-109 323.0 COG3637@1|root,COG3637@2|Bacteria,1N2XM@1224|Proteobacteria,1SIDP@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Outer membrane protein beta-barrel domain - - - - - - - - - - - - OMP_b-brl k141_37455_1 521393.JH806634_gene2238 1.7e-39 142.0 COG1595@1|root,COG1595@2|Bacteria,2GJ02@201174|Actinobacteria,4D431@85005|Actinomycetales 201174|Actinobacteria K Belongs to the sigma-70 factor family. ECF subfamily sigH GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_37455_2 857087.Metme_2999 1.64e-18 83.2 29DWE@1|root,300UA@2|Bacteria,1RDK5@1224|Proteobacteria,1S3V9@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Cytochrome P460 - - - - - - - - - - - - Cytochrome_P460 k141_16157_2 1453501.JELR01000002_gene796 4.15e-87 261.0 COG0745@1|root,COG0745@2|Bacteria,1RD9E@1224|Proteobacteria,1S3PS@1236|Gammaproteobacteria,46DAR@72275|Alteromonadaceae 1236|Gammaproteobacteria T Helix-turn-helix domain - - - - - - - - - - - - HTH_17,Response_reg k141_16157_3 1042377.AFPJ01000043_gene944 7.23e-234 650.0 COG0617@1|root,COG0617@2|Bacteria,1MU2X@1224|Proteobacteria,1RPFJ@1236|Gammaproteobacteria,4641Q@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate cca GO:0003674,GO:0003824,GO:0004652,GO:0004810,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0070566,GO:0071704,GO:0090304,GO:1901360,GO:1990817 2.7.7.72 ko:K00974 ko03013,map03013 - R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016 - - - HD,PolyA_pol,PolyA_pol_RNAbd k141_16157_4 1279017.AQYJ01000020_gene1256 1.07e-79 243.0 COG1028@1|root,COG1028@2|Bacteria,1MUUV@1224|Proteobacteria,1RMJU@1236|Gammaproteobacteria,466CG@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) ycdF - 1.5.1.33 ko:K03793 - - - - ko00000,ko01000 - - - adh_short_C2 k141_22106_1 1294265.JCM21738_1955 6.07e-111 328.0 COG1301@1|root,COG1301@2|Bacteria,1TPME@1239|Firmicutes,4H9T7@91061|Bacilli,1ZCSU@1386|Bacillus 91061|Bacilli C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family gltP - - - - - - - - - - - SDF k141_9146_1 1294265.JCM21738_4925 4.21e-20 81.6 29SA3@1|root,30DEK@2|Bacteria,1UB7H@1239|Firmicutes,4IMK7@91061|Bacilli,1ZKBV@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF4083) - - - - - - - - - - - - DUF4083 k141_9146_2 1243664.CAVL020000047_gene2330 2.84e-23 89.4 2EAGM@1|root,334JW@2|Bacteria,1VFQ7@1239|Firmicutes,4HNMW@91061|Bacilli,1ZHUK@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_36234_1 1294265.JCM21738_4926 3.74e-187 525.0 COG0673@1|root,COG0673@2|Bacteria,1V157@1239|Firmicutes,4HF8V@91061|Bacilli,1ZGKA@1386|Bacillus 91061|Bacilli S Oxidoreductase family, C-terminal alpha/beta domain - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C k141_4275_1 930169.B5T_02704 8.34e-27 107.0 COG2025@1|root,COG2025@2|Bacteria,1MUFI@1224|Proteobacteria,1RMK7@1236|Gammaproteobacteria,1XHMV@135619|Oceanospirillales 135619|Oceanospirillales C Electron transfer flavoprotein etfA - - ko:K03522 - - - - ko00000,ko04147 - - - ETF,ETF_alpha k141_4275_2 391165.GbCGDNIH1_2094 2.93e-31 117.0 COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,2TR4J@28211|Alphaproteobacteria,2JPSB@204441|Rhodospirillales 204441|Rhodospirillales C Electron transfer flavoprotein, beta subunit etfB - - ko:K03521 - - - - ko00000 - - - ETF k141_31422_1 1042377.AFPJ01000020_gene2057 2.22e-62 207.0 COG1502@1|root,COG1502@2|Bacteria,1MUDJ@1224|Proteobacteria,1RMIF@1236|Gammaproteobacteria,4649V@72275|Alteromonadaceae 1236|Gammaproteobacteria I Phospholipase D. Active site motifs. - - - ko:K06132 ko00564,ko01100,map00564,map01100 - R11062 RC00017 ko00000,ko00001,ko01000 - - - PLDc_2 k141_14910_1 977880.RALTA_A2642 9.47e-08 52.8 COG0773@1|root,COG0773@2|Bacteria,1MUC5@1224|Proteobacteria,2VIX5@28216|Betaproteobacteria,1K14Y@119060|Burkholderiaceae 28216|Betaproteobacteria M Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate mpl - 6.3.2.45 ko:K02558 - - - - ko00000,ko01000 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M k141_1802_1 1117379.BABA_26091 1.21e-85 262.0 COG0438@1|root,COG0438@2|Bacteria,1UZT6@1239|Firmicutes,4HFIA@91061|Bacilli,1ZEN6@1386|Bacillus 91061|Bacilli M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 k141_5629_2 203122.Sde_1930 1.14e-135 413.0 COG0845@1|root,COG5569@1|root,COG0845@2|Bacteria,COG5569@2|Bacteria,1MVAS@1224|Proteobacteria,1RPBZ@1236|Gammaproteobacteria,464X2@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family cusB - - ko:K07798 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.6.1.4,8.A.1 - - CusF_Ec,HlyD_D23,HlyD_D4 k141_27163_1 218284.CCDN010000002_gene2141 2.92e-121 356.0 COG0160@1|root,COG0160@2|Bacteria,1VS6F@1239|Firmicutes,4H9M7@91061|Bacilli,1ZAZ9@1386|Bacillus 91061|Bacilli E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family gabT - 2.6.1.19 ko:K00823 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 M00027 R00908,R01648 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 k141_849_1 1042377.AFPJ01000036_gene1141 1.21e-122 361.0 COG1305@1|root,COG1305@2|Bacteria,1R72E@1224|Proteobacteria,1S1BR@1236|Gammaproteobacteria 1236|Gammaproteobacteria E COG1305 Transglutaminase-like enzymes - - - - - - - - - - - - Transglut_core k141_18728_1 218284.CCDN010000001_gene23 2.92e-120 351.0 COG0552@1|root,COG0552@2|Bacteria,1TPRI@1239|Firmicutes,4HA6A@91061|Bacilli,1ZB46@1386|Bacillus 91061|Bacilli U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) ftsY - - ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2,3.A.5.7 - - SRP54,SRP54_N k141_17317_1 223926.28806620 2.38e-285 780.0 COG1092@1|root,COG1092@2|Bacteria,1MUGB@1224|Proteobacteria,1RN7Z@1236|Gammaproteobacteria,1XTVB@135623|Vibrionales 135623|Vibrionales J Specifically methylates the cytosine at position 1962 (m5C1962) of 23S rRNA rlmI - 2.1.1.191 ko:K06969 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_SAM k141_17317_2 223926.28806627 1.1e-80 239.0 2E73W@1|root,331NB@2|Bacteria,1N81U@1224|Proteobacteria,1SCT8@1236|Gammaproteobacteria,1XXHR@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF2750) SO1991 - - - - - - - - - - - DUF2750 k141_17317_3 1116375.VEJY3_07760 1.19e-207 597.0 COG0457@1|root,COG2199@1|root,COG0457@2|Bacteria,COG2199@2|Bacteria,1NW5T@1224|Proteobacteria,1SPKH@1236|Gammaproteobacteria,1XT8U@135623|Vibrionales 135623|Vibrionales T Tetratricopeptide repeat - - - - - - - - - - - - GGDEF,TPR_12,TPR_7,TPR_8 k141_9147_1 1453501.JELR01000001_gene2503 3.21e-138 407.0 COG4783@1|root,COG4783@2|Bacteria,1QTUQ@1224|Proteobacteria,1T1HY@1236|Gammaproteobacteria,46DF2@72275|Alteromonadaceae 1236|Gammaproteobacteria S Oxygen tolerance batD - - - - - - - - - - - BatD k141_22108_1 1048834.TC41_2936 8.98e-05 44.7 COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,4HC17@91061|Bacilli 91061|Bacilli K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_20849_1 218284.CCDN010000001_gene609 3.1e-39 144.0 COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,4HB85@91061|Bacilli,1ZAS4@1386|Bacillus 91061|Bacilli J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner valS GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 k141_11568_1 574376.BAMA_20155 9.12e-265 759.0 COG1404@1|root,COG1404@2|Bacteria,1TPH1@1239|Firmicutes,4HBQH@91061|Bacilli,1ZBS0@1386|Bacillus 91061|Bacilli O Belongs to the peptidase S8 family prtS - 3.4.21.110,3.4.21.96 ko:K01361,ko:K08652 - - - - ko00000,ko01000,ko01002,ko03110 - - - FIVAR,Gram_pos_anchor,Inhibitor_I9,PA,Peptidase_S8,SLH,YSIRK_signal,fn3_5 k141_34054_1 634956.Geoth_1330 1.11e-78 245.0 COG2195@1|root,COG2195@2|Bacteria,1TP3A@1239|Firmicutes,4HA04@91061|Bacilli,1WE9Q@129337|Geobacillus 91061|Bacilli E Peptidase family M28 yqjE - 3.4.11.14,3.4.11.4 ko:K01258,ko:K01263 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20,Peptidase_M28 k141_22137_1 768671.ThimaDRAFT_0214 4.13e-87 285.0 COG0587@1|root,COG0587@2|Bacteria,1MUE4@1224|Proteobacteria,1RQA8@1236|Gammaproteobacteria,1WW62@135613|Chromatiales 135613|Chromatiales L DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase dnaE2 - 2.7.7.7 ko:K14162 - - - - ko00000,ko01000,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon k141_12819_2 946235.CAER01000031_gene779 1.02e-11 64.3 COG2105@1|root,COG3703@1|root,COG2105@2|Bacteria,COG3703@2|Bacteria,1V4XC@1239|Firmicutes,4HH0F@91061|Bacilli 91061|Bacilli P AIG2-like family ykqA - - - - - - - - - - - AIG2_2,GGACT k141_17333_1 1472418.BBJC01000005_gene2156 2.66e-64 211.0 COG0520@1|root,COG0520@2|Bacteria,1N124@1224|Proteobacteria,2TZXB@28211|Alphaproteobacteria 28211|Alphaproteobacteria E aminotransferase class V - - - - - - - - - - - - Aminotran_5 k141_17333_2 1492922.GY26_08875 2.53e-13 66.2 COG1522@1|root,COG1522@2|Bacteria,1RDB3@1224|Proteobacteria,1S2E1@1236|Gammaproteobacteria,1JB0C@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria K helix_turn_helix ASNC type ybaO - - ko:K05800 - - - - ko00000,ko03000 - - - AsnC_trans_reg,HTH_24,HTH_AsnC-type k141_3029_1 406124.ACPC01000009_gene1484 2.17e-40 142.0 COG1595@1|root,COG1595@2|Bacteria,1V8BF@1239|Firmicutes,4HJ64@91061|Bacilli,1ZEJV@1386|Bacillus 91061|Bacilli K Sigma-70, region 4 - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_16176_1 218284.CCDN010000002_gene1988 2.62e-114 348.0 COG0046@1|root,COG0046@2|Bacteria,1TPAS@1239|Firmicutes,4HB3N@91061|Bacilli,1ZCN8@1386|Bacillus 91061|Bacilli F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL purL GO:0003674,GO:0003824,GO:0004642,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C k141_35304_2 1280001.BAOA01000074_gene3438 1.25e-136 388.0 COG0778@1|root,COG0778@2|Bacteria,1N95W@1224|Proteobacteria,1RSDH@1236|Gammaproteobacteria,1XVNT@135623|Vibrionales 135623|Vibrionales C Nitroreductase family nfnB - 1.5.1.34 ko:K10679 ko00633,ko01120,map00633,map01120 - R08014,R08017,R08042 RC00250 ko00000,ko00001,ko01000 - - - Nitroreductase k141_25859_1 218284.CCDN010000001_gene1173 1.08e-119 375.0 COG0699@1|root,COG0699@2|Bacteria,1TR0Q@1239|Firmicutes,4HBAC@91061|Bacilli,1ZAXM@1386|Bacillus 91061|Bacilli S Dynamin family ypbR GO:0000910,GO:0003674,GO:0003824,GO:0003924,GO:0005575,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022402,GO:0022607,GO:0031224,GO:0032506,GO:0044085,GO:0044425,GO:0051301,GO:0071840,GO:0090529 - - - - - - - - - - Dynamin_N k141_19796_1 1294265.JCM21738_5110 1.72e-112 332.0 COG2200@1|root,COG2200@2|Bacteria,1TQ94@1239|Firmicutes,4HAY4@91061|Bacilli,1ZB7X@1386|Bacillus 91061|Bacilli T Putative diguanylate phosphodiesterase - - - - - - - - - - - - CBS,EAL,GGDEF k141_22138_1 1453501.JELR01000002_gene948 2.39e-16 75.1 COG3166@1|root,COG3166@2|Bacteria,1RF1S@1224|Proteobacteria,1S3S0@1236|Gammaproteobacteria,467DK@72275|Alteromonadaceae 1236|Gammaproteobacteria NU COG3166 Tfp pilus assembly protein PilN pilN - - ko:K02663 - - - - ko00000,ko02035,ko02044 - - - PilN k141_10384_1 7668.SPU_015598-tr 5.07e-10 62.8 KOG4651@1|root,KOG4651@2759|Eukaryota,38CH1@33154|Opisthokonta,3BGMN@33208|Metazoa,3CYG1@33213|Bilateria 33208|Metazoa G N-acetylgalactosamine 4-O-sulfotransferase activity CHST14 GO:0000139,GO:0001537,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005794,GO:0006022,GO:0006023,GO:0006024,GO:0006029,GO:0006082,GO:0006790,GO:0006807,GO:0008146,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0012505,GO:0016020,GO:0016021,GO:0016053,GO:0016740,GO:0016782,GO:0017144,GO:0019538,GO:0019752,GO:0030166,GO:0030203,GO:0030205,GO:0030208,GO:0031090,GO:0031224,GO:0031984,GO:0032787,GO:0034645,GO:0042301,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044272,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044425,GO:0044431,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0050651,GO:0050655,GO:0071704,GO:0072330,GO:0098588,GO:0098791,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903510 2.8.2.35,2.8.2.5 ko:K07779,ko:K08105 ko00532,map00532 - R02180,R10873 RC00007,RC00231 ko00000,ko00001,ko01000,ko01003 - - - Sulfotransfer_2 k141_10384_2 766499.C357_21372 4.06e-19 85.5 COG1216@1|root,COG1216@2|Bacteria,1MZBS@1224|Proteobacteria,2UEUD@28211|Alphaproteobacteria 28211|Alphaproteobacteria S N-terminal domain of galactosyltransferase - - - - - - - - - - - - Glyco_transf_7C k141_31432_1 1279017.AQYJ01000024_gene1172 4.52e-175 517.0 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,1RMPV@1236|Gammaproteobacteria,465IY@72275|Alteromonadaceae 1236|Gammaproteobacteria F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdA - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN k141_23476_1 472759.Nhal_2235 2.49e-31 122.0 COG0224@1|root,COG0224@2|Bacteria,1RIE5@1224|Proteobacteria,1S3ZW@1236|Gammaproteobacteria 1236|Gammaproteobacteria C ATP synthase gamma subunit - - - ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt k141_14068_1 218284.CCDN010000008_gene4220 4.37e-35 123.0 COG4980@1|root,COG4980@2|Bacteria,1VFY7@1239|Firmicutes,4HNWV@91061|Bacilli,1ZEKS@1386|Bacillus 91061|Bacilli S COG4980 Gas vesicle protein ytxH - - - - - - - - - - - YtxH k141_14068_2 218284.CCDN010000008_gene4219 1.86e-46 158.0 COG4768@1|root,COG4768@2|Bacteria,1VAXN@1239|Firmicutes,4HM93@91061|Bacilli,1ZGYS@1386|Bacillus 91061|Bacilli S protein containing a divergent version of the methyl-accepting chemotaxis-like domain ytxG - - - - - - - - - - - DUF948 k141_35305_1 935837.JAEK01000040_gene3721 2.44e-54 189.0 COG2200@1|root,COG3300@1|root,COG2200@2|Bacteria,COG3300@2|Bacteria,1TS8B@1239|Firmicutes,4ISKA@91061|Bacilli,1ZDC3@1386|Bacillus 91061|Bacilli T Bacterial signalling protein N terminal repeat - - 2.7.7.65 ko:K21023 ko02025,map02025 - - - ko00000,ko00001,ko01000 - - - EAL,GAF,GGDEF,MASE3,MHYT,PAS_4,PAS_9 k141_867_1 1298593.TOL_1373 1.86e-166 473.0 COG0027@1|root,COG0027@2|Bacteria,1N3KA@1224|Proteobacteria,1RNTW@1236|Gammaproteobacteria,1XHPS@135619|Oceanospirillales 135619|Oceanospirillales F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate purT - 2.1.2.2 ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04325,R04326 RC00026,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp,Epimerase k141_7815_1 1116375.VEJY3_24366 2.61e-103 316.0 COG1315@1|root,COG1315@2|Bacteria,1R40D@1224|Proteobacteria,1RZ2U@1236|Gammaproteobacteria,1XT9Y@135623|Vibrionales 135623|Vibrionales L polymerase, most proteins contain PALM domain, HD hydrolase domain and Zn-ribbon domain - - - ko:K09749 - - - - ko00000 - - - FapA k141_7815_2 1116375.VEJY3_24361 8.08e-148 418.0 COG2866@1|root,COG2866@2|Bacteria,1N9AY@1224|Proteobacteria,1RRGU@1236|Gammaproteobacteria,1XUQH@135623|Vibrionales 135623|Vibrionales E Zinc carboxypeptidase - - - ko:K14054 - - - - ko00000 - - - Peptidase_M14 k141_35502_2 768671.ThimaDRAFT_0215 1.92e-17 83.2 COG0389@1|root,COG0389@2|Bacteria,1MU5X@1224|Proteobacteria,1S28B@1236|Gammaproteobacteria 1236|Gammaproteobacteria L nucleotidyltransferase DNA polymerase involved in DNA repair imuB - - ko:K14161 - - - - ko00000,ko03400 - - - IMS k141_9421_1 218284.CCDN010000006_gene3740 2.41e-108 319.0 COG1609@1|root,COG1609@2|Bacteria,1TPZM@1239|Firmicutes,4H9ZT@91061|Bacilli,1ZB2U@1386|Bacillus 91061|Bacilli K Transcriptional regulator malR - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_1,Peripla_BP_3 k141_31549_1 42565.FP66_13315 1.41e-137 407.0 COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,1RMDD@1236|Gammaproteobacteria,1XI2A@135619|Oceanospirillales 135619|Oceanospirillales O Heat shock 70 kDa protein dnaK - - ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 - - HSP70 k141_22430_1 1122194.AUHU01000003_gene2122 6.28e-78 252.0 COG1538@1|root,COG1538@2|Bacteria,1RDVP@1224|Proteobacteria,1S9NY@1236|Gammaproteobacteria 1236|Gammaproteobacteria MU Outer membrane efflux protein - - - - - - - - - - - - OEP k141_36404_1 218284.CCDN010000010_gene4346 2.59e-159 455.0 COG0201@1|root,COG0201@2|Bacteria,1TPHB@1239|Firmicutes,4HAWH@91061|Bacilli,1ZCEG@1386|Bacillus 91061|Bacilli U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently secY GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5 - - SecY k141_11801_1 218284.CCDN010000001_gene1434 1.13e-25 101.0 2CC31@1|root,2Z920@2|Bacteria,1UZSZ@1239|Firmicutes,4HCVB@91061|Bacilli,1ZGJ7@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_1956_1 935836.JAEL01000148_gene4946 2.32e-42 152.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,1ZBXB@1386|Bacillus 91061|Bacilli V COG1132 ABC-type multidrug transport system, ATPase and permease components yheI - - ko:K18216,ko:K18889 ko02010,map02010 M00635,M00707 - - ko00000,ko00001,ko00002,ko01504,ko02000 3.A.1,3.A.1.106.13,3.A.1.106.5 - - ABC_membrane,ABC_tran k141_20003_1 1042377.AFPJ01000038_gene1123 5.06e-40 142.0 COG3173@1|root,COG3173@2|Bacteria,1MWAK@1224|Proteobacteria,1RNB4@1236|Gammaproteobacteria,465F2@72275|Alteromonadaceae 1236|Gammaproteobacteria S Aminoglycoside phosphotransferase - - - - - - - - - - - - APH k141_20003_2 1279017.AQYJ01000018_gene822 7.84e-245 678.0 COG1960@1|root,COG1960@2|Bacteria,1MU2V@1224|Proteobacteria,1RNJH@1236|Gammaproteobacteria,46475@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1960 Acyl-CoA dehydrogenases - - 1.3.8.7 ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_20003_3 1279017.AQYJ01000018_gene823 3.38e-92 276.0 COG0406@1|root,COG0406@2|Bacteria,1RB0S@1224|Proteobacteria,1S2YG@1236|Gammaproteobacteria,466J4@72275|Alteromonadaceae 1236|Gammaproteobacteria G Phosphoglycerate mutase family - - - - - - - - - - - - His_Phos_1 k141_20003_4 1279017.AQYJ01000018_gene824 1.79e-162 461.0 COG0583@1|root,COG0583@2|Bacteria,1NYPZ@1224|Proteobacteria,1RXYS@1236|Gammaproteobacteria,46558@72275|Alteromonadaceae 1236|Gammaproteobacteria K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_7033_1 1499967.BAYZ01000019_gene6264 2.64e-36 130.0 COG0546@1|root,COG0546@2|Bacteria,2NPKQ@2323|unclassified Bacteria 2|Bacteria S Haloacid dehalogenase-like hydrolase gph - 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 - R01334 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 k141_7033_2 521674.Plim_3386 4.75e-15 76.3 COG0531@1|root,COG0531@2|Bacteria,2IX7G@203682|Planctomycetes 203682|Planctomycetes E Amino acid permease - - - ko:K03294 - - - - ko00000 2.A.3.2 - - AA_permease_2 k141_29408_1 218284.CCDN010000003_gene2989 7.1e-258 739.0 COG1197@1|root,COG1197@2|Bacteria,1TPF1@1239|Firmicutes,4H9NB@91061|Bacilli,1ZBAK@1386|Bacillus 91061|Bacilli L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd - - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF k141_1068_1 42565.FP66_06110 0.0 903.0 COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,1RNCU@1236|Gammaproteobacteria,1XI5I@135619|Oceanospirillales 135619|Oceanospirillales L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd - - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF k141_1068_2 1397528.Q671_12845 8.64e-15 72.8 COG0057@1|root,COG0057@2|Bacteria,1MZE4@1224|Proteobacteria,1RMSI@1236|Gammaproteobacteria,1XHW4@135619|Oceanospirillales 135619|Oceanospirillales G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family gapA - 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N k141_9423_2 1345695.CLSA_c34530 4.79e-19 79.3 2CDFN@1|root,33CYY@2|Bacteria,1VEJK@1239|Firmicutes,24RI3@186801|Clostridia,36PEA@31979|Clostridiaceae 186801|Clostridia - - - - - - - - - - - - - - - k141_1957_1 1042377.AFPJ01000007_gene1870 3.59e-51 182.0 COG3127@1|root,COG3127@2|Bacteria,1QXGA@1224|Proteobacteria,1T3BG@1236|Gammaproteobacteria,467CX@72275|Alteromonadaceae 1236|Gammaproteobacteria Q COG0577 ABC-type antimicrobial peptide transport system, permease component - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX k141_16344_1 1294265.JCM21738_1135 2.83e-97 291.0 COG0685@1|root,COG0685@2|Bacteria,1UHX4@1239|Firmicutes,4ITQH@91061|Bacilli 91061|Bacilli E Methylenetetrahydrofolate reductase - - - - - - - - - - - - MTHFR k141_16344_2 1294265.JCM21738_1136 5.15e-25 102.0 COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1TPYV@1239|Firmicutes,4HBER@91061|Bacilli,1ZBGN@1386|Bacillus 91061|Bacilli E Methionine synthase metH - 2.1.1.13 ko:K00548 ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230 M00017 R00946,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans k141_23765_2 701176.VIBRN418_00325 4.3e-196 560.0 COG4938@1|root,COG4938@2|Bacteria 2|Bacteria S AAA ATPase domain - - - - - - - - - - - - AAA_15,AAA_21,DUF3696 k141_11833_2 1499685.CCFJ01000012_gene1767 1.37e-78 245.0 COG4585@1|root,COG4585@2|Bacteria,1TRFX@1239|Firmicutes,4HD1M@91061|Bacilli,1ZDHA@1386|Bacillus 91061|Bacilli T Signal transduction histidine kinase - - - - - - - - - - - - HisKA_3 k141_16364_1 1453501.JELR01000001_gene3128 4.81e-160 462.0 COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,1RMBG@1236|Gammaproteobacteria,464KY@72275|Alteromonadaceae 1236|Gammaproteobacteria H Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control pcnB GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004652,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006276,GO:0006378,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0031123,GO:0031124,GO:0034641,GO:0043170,GO:0043412,GO:0043631,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070566,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 2.7.7.19 ko:K00970 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - PolyA_pol,PolyA_pol_RNAbd,PolyA_pol_arg_C k141_16364_2 1042377.AFPJ01000010_gene1435 1.48e-68 211.0 COG0801@1|root,COG0801@2|Bacteria,1MZH8@1224|Proteobacteria,1S63J@1236|Gammaproteobacteria,467BR@72275|Alteromonadaceae 1236|Gammaproteobacteria H COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase folK GO:0000287,GO:0003674,GO:0003824,GO:0003848,GO:0005488,GO:0016740,GO:0016772,GO:0016778,GO:0043167,GO:0043169,GO:0046872 2.7.6.3 ko:K00950 ko00790,ko01100,map00790,map01100 M00126,M00841 R03503 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - iECDH1ME8569_1439.ECDH1ME8569_0136,iEcDH1_1363.EcDH1_3460,iJN746.PP_4698,iSBO_1134.SBO_0131 HPPK k141_3246_1 240302.BN982_00266 1.65e-94 288.0 COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,4HA98@91061|Bacilli,3NEFE@45667|Halobacillus 91061|Bacilli L helicase superfamily c-terminal domain cshB GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0070035,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 3.6.4.13 ko:K05592,ko:K18692 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,Helicase_C k141_32959_1 218284.CCDN010000008_gene4192 2.39e-98 298.0 COG0624@1|root,COG0624@2|Bacteria,1TPEG@1239|Firmicutes,4HC14@91061|Bacilli,1ZBI2@1386|Bacillus 91061|Bacilli E Dipeptidase ytjP - 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20 k141_15122_1 1219076.N646_3948 6.05e-37 129.0 2BHEN@1|root,32BGN@2|Bacteria,1QK9U@1224|Proteobacteria,1TIDB@1236|Gammaproteobacteria,1XYX3@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_15122_2 1116375.VEJY3_17786 2.89e-83 247.0 2DNJ4@1|root,32XS7@2|Bacteria,1RJNG@1224|Proteobacteria,1S8KV@1236|Gammaproteobacteria,1XX9F@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_15122_3 1219076.N646_3950 5.97e-210 581.0 COG4989@1|root,COG4989@2|Bacteria,1MY3G@1224|Proteobacteria,1RRIC@1236|Gammaproteobacteria,1XTIM@135623|Vibrionales 135623|Vibrionales S oxidoreductase, aldo keto reductase 2 ydhF - - - - - - - - - - - Aldo_ket_red k141_5797_2 218284.CCDN010000004_gene3049 1.28e-69 223.0 COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,4HCRI@91061|Bacilli,1ZQ2S@1386|Bacillus 91061|Bacilli C Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain - - - - - - - - - - - - Pyr_redox_2,Pyr_redox_dim k141_7067_1 218284.CCDN010000006_gene3584 8.12e-165 468.0 COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,4HADX@91061|Bacilli 91061|Bacilli E Belongs to the aspartokinase family - - - - - - - - - - - - AA_kinase,ACT_7 k141_10486_2 326442.PSHAb0009 1.97e-22 92.4 COG2372@1|root,COG2372@2|Bacteria,1NBCA@1224|Proteobacteria,1SCRG@1236|Gammaproteobacteria,2Q2RR@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria S CopC domain - - - ko:K07156 - - - - ko00000,ko02000 9.B.62.2 - - CopC k141_10486_3 1453501.JELR01000001_gene2244 2.79e-136 394.0 COG3667@1|root,COG3667@2|Bacteria,1MXW6@1224|Proteobacteria,1RZEY@1236|Gammaproteobacteria,465EA@72275|Alteromonadaceae 1236|Gammaproteobacteria P protein involved in copper resistance pcoB - - ko:K07233 - - - - ko00000 - - - CopB k141_10486_4 1453501.JELR01000001_gene2245 4.92e-195 560.0 COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,1RQ4N@1236|Gammaproteobacteria,4648E@72275|Alteromonadaceae 1236|Gammaproteobacteria Q multicopper oxidases pcoA - - - - - - - - - - - CopB,Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3 k141_20033_2 525897.Dbac_1355 2.84e-13 79.3 COG1061@1|root,COG1061@2|Bacteria,1QWMJ@1224|Proteobacteria,42NXF@68525|delta/epsilon subdivisions,2WJWA@28221|Deltaproteobacteria,2M96Z@213115|Desulfovibrionales 28221|Deltaproteobacteria L PFAM type III restriction protein res subunit - - - - - - - - - - - - Helicase_C,ResIII k141_4426_3 1283337.B0ZSJ0_BPHA1 2.56e-118 341.0 4QBB4@10239|Viruses,4QXRP@35237|dsDNA viruses no RNA stage,4QPYU@28883|Caudovirales,4QKB4@10662|Myoviridae 10662|Myoviridae S Phage antitermination protein Q - - - - - - - - - - - - - k141_12974_1 1396.DJ87_4776 2.63e-55 184.0 29H5Q@1|root,30439@2|Bacteria,1V63Q@1239|Firmicutes,4HHR2@91061|Bacilli,1ZE9T@1386|Bacillus 91061|Bacilli S Nuclease-related domain - - - - - - - - - - - - NERD k141_5798_2 1453501.JELR01000002_gene485 3.68e-11 62.8 COG2365@1|root,COG2365@2|Bacteria,1R4XF@1224|Proteobacteria,1RMPM@1236|Gammaproteobacteria,466PW@72275|Alteromonadaceae 1236|Gammaproteobacteria T Tyrosine phosphatase family - - - - - - - - - - - - Y_phosphatase3 k141_24757_1 344747.PM8797T_03349 5.35e-147 428.0 COG0527@1|root,COG0527@2|Bacteria,2IY8N@203682|Planctomycetes 203682|Planctomycetes E aspartate kinase, monofunctional class - - 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase k141_24757_2 472759.Nhal_2707 2.85e-85 265.0 COG0160@1|root,COG0160@2|Bacteria,1MWY6@1224|Proteobacteria,1RQKU@1236|Gammaproteobacteria,1WXFB@135613|Chromatiales 135613|Chromatiales H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - 2.6.1.76 ko:K00836 ko00260,ko01100,ko01120,ko01210,ko01230,map00260,map01100,map01120,map01210,map01230 M00033 R06977 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 k141_20034_1 1294265.JCM21738_3451 2.91e-11 63.9 COG3729@1|root,COG3729@2|Bacteria,1V71P@1239|Firmicutes,4HJ8A@91061|Bacilli,1ZGZA@1386|Bacillus 91061|Bacilli S general stress protein gsiB - - ko:K06884 - - - - ko00000 - - - KGG,LEA_5 k141_36421_1 1279017.AQYJ01000029_gene3646 2e-209 596.0 COG1506@1|root,COG1506@2|Bacteria,1MUJ3@1224|Proteobacteria,1RRN4@1236|Gammaproteobacteria,465BC@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases pqqM - - - - - - - - - - - PD40,Peptidase_S9 k141_34244_1 1453501.JELR01000001_gene2929 5.23e-88 285.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,466AN@72275|Alteromonadaceae 1236|Gammaproteobacteria V AcrB/AcrD/AcrF family bepG - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran k141_31571_2 582402.Hbal_1596 2.11e-24 103.0 COG1629@1|root,COG4771@2|Bacteria,1MWKN@1224|Proteobacteria,2TTFY@28211|Alphaproteobacteria,4415P@69657|Hyphomonadaceae 28211|Alphaproteobacteria P TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_17431_1 1116375.VEJY3_01425 5.07e-113 327.0 COG3061@1|root,COG3061@2|Bacteria,1R4XK@1224|Proteobacteria,1S430@1236|Gammaproteobacteria,1XXHC@135623|Vibrionales 135623|Vibrionales M COG3061 Cell envelope opacity-associated protein A - - - ko:K07269 - - - - ko00000 - - - OapA,OapA_N k141_17431_2 1116375.VEJY3_01430 8.36e-95 277.0 COG2153@1|root,COG2153@2|Bacteria,1MZHA@1224|Proteobacteria,1S9IF@1236|Gammaproteobacteria,1XXDT@135623|Vibrionales 135623|Vibrionales S Acetyltransferase (GNAT) domain elaA - - ko:K02348 - - - - ko00000 - - - Acetyltransf_10 k141_17431_3 223926.28805270 5.52e-315 860.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RQ36@1236|Gammaproteobacteria,1XV3X@135623|Vibrionales 135623|Vibrionales JKL Belongs to the DEAD box helicase family dbpA - 3.6.4.13 ko:K05591 - - - - ko00000,ko01000,ko03009 - - - DEAD,DbpA,Helicase_C k141_17431_4 1116375.VEJY3_01440 4.48e-113 327.0 COG0664@1|root,COG0664@2|Bacteria,1RIU1@1224|Proteobacteria,1S6NE@1236|Gammaproteobacteria,1XWYV@135623|Vibrionales 135623|Vibrionales T Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - - - - - - - - - - cNMP_binding k141_17431_5 223926.28805272 0.0 1186.0 COG0737@1|root,COG0737@2|Bacteria,1MU11@1224|Proteobacteria,1RMQV@1236|Gammaproteobacteria,1XSV2@135623|Vibrionales 135623|Vibrionales F Belongs to the 5'-nucleotidase family cpdB - 3.1.3.6,3.1.4.16 ko:K01119 ko00230,ko00240,map00230,map00240 - R01562,R01877,R02148,R02370,R03537,R03538,R03929,R05135 RC00078,RC00296 ko00000,ko00001,ko01000 - - - 5_nucleotid_C,Metallophos k141_17431_6 1219076.N646_2482 4.94e-193 537.0 COG0007@1|root,COG0007@2|Bacteria,1MUI0@1224|Proteobacteria,1RM9V@1236|Gammaproteobacteria,1XSWE@135623|Vibrionales 135623|Vibrionales H Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme cysG - 1.3.1.76,2.1.1.107,4.99.1.4 ko:K02302,ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02864,R03194,R03947 RC00003,RC00871,RC01012,RC01034 ko00000,ko00001,ko00002,ko01000 - - - CysG_dimeriser,NAD_binding_7,Sirohm_synth_M,TP_methylase k141_17431_7 1280001.BAOA01000021_gene786 5.18e-220 606.0 COG0175@1|root,COG0175@2|Bacteria,1MUCZ@1224|Proteobacteria,1RNAD@1236|Gammaproteobacteria,1XTPJ@135623|Vibrionales 135623|Vibrionales H Sulfate adenylyltransferase subunit 2 cysD GO:0003674,GO:0003824,GO:0004779,GO:0004781,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0044237,GO:0070566 2.7.7.4 ko:K00957 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176,M00596 R00529,R04929 RC02809,RC02889 ko00000,ko00001,ko00002,ko01000 - - - PAPS_reduct k141_17431_8 674977.VMC_03690 2.8e-310 851.0 COG2895@1|root,COG2895@2|Bacteria,1MUD9@1224|Proteobacteria,1RME4@1236|Gammaproteobacteria,1XSCY@135623|Vibrionales 135623|Vibrionales H Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily cysN GO:0003674,GO:0003824,GO:0004779,GO:0004781,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0044237,GO:0070566 2.7.7.4 ko:K00956 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176,M00596 R00529,R04929 RC02809,RC02889 ko00000,ko00001,ko00002,ko01000 - - - GTP_EFTU k141_5800_1 218284.CCDN010000004_gene3137 1.1e-110 322.0 COG0702@1|root,COG0702@2|Bacteria,1TS7J@1239|Firmicutes,4HFT3@91061|Bacilli,1ZGA3@1386|Bacillus 91061|Bacilli GM NAD(P)H-binding yheG - - - - - - - - - - - NAD_binding_10 k141_32961_1 218284.CCDN010000001_gene218 5.1e-226 632.0 COG0365@1|root,COG0365@2|Bacteria,1TQTI@1239|Firmicutes,4H9PN@91061|Bacilli,1ZCDC@1386|Bacillus 91061|Bacilli I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases ytcI GO:0003674,GO:0003824,GO:0003996,GO:0004321,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0015645,GO:0016053,GO:0016405,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0016874,GO:0016877,GO:0016878,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901576 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 - - - AMP-binding,AMP-binding_C k141_29440_3 1131730.BAVI_14424 1.82e-94 283.0 29WX8@1|root,30IJ9@2|Bacteria,1UJ4S@1239|Firmicutes,4IT1A@91061|Bacilli,1ZCC6@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_28061_1 279010.BL00983 3.41e-63 207.0 2DB9U@1|root,2Z7Z6@2|Bacteria,1TR67@1239|Firmicutes,4HCTZ@91061|Bacilli,1ZEZR@1386|Bacillus 91061|Bacilli S Phage portal protein, SPP1 Gp6-like - - - - - - - - - - - - Phage_prot_Gp6 k141_28061_2 1334046.AYTB01000008_gene2311 4.73e-96 296.0 COG2369@1|root,COG2369@2|Bacteria,1V2JT@1239|Firmicutes,4HFSR@91061|Bacilli 91061|Bacilli S Phage Mu protein F like protein - - - - - - - - - - - - Phage_Mu_F k141_7069_2 187764.Q9AZ47_9CAUD 1.11e-19 92.8 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QNBD@10744|Podoviridae 10744|Podoviridae S outer membrane - GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0008150,GO:0016032,GO:0019012,GO:0019058,GO:0019062,GO:0022610,GO:0042802,GO:0044403,GO:0044406,GO:0044419,GO:0044423,GO:0044650,GO:0051704,GO:0098015,GO:0098024 - - - - - - - - - - - k141_17432_1 796606.BMMGA3_06295 6.8e-100 305.0 COG0442@1|root,COG0442@2|Bacteria,1TRBV@1239|Firmicutes,4H9NN@91061|Bacilli,1ZD7M@1386|Bacillus 91061|Bacilli J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS proS - 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_2b,tRNA_edit k141_4428_1 218284.CCDN010000001_gene815 2.61e-136 391.0 COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,4HB0C@91061|Bacilli,1ZBK5@1386|Bacillus 91061|Bacilli NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB comGA - - ko:K02243 - M00429 - - ko00000,ko00002,ko02044 3.A.14.1 - - T2SSE k141_15124_1 218284.CCDN010000001_gene1072 4.21e-57 181.0 COG1266@1|root,COG1266@2|Bacteria,1V4WK@1239|Firmicutes,4HHKM@91061|Bacilli,1ZEBP@1386|Bacillus 91061|Bacilli S metal-dependent membrane protease ypbD - - ko:K07052 - - - - ko00000 - - - Abi k141_15124_2 218284.CCDN010000001_gene1073 3.29e-08 55.1 COG1388@1|root,COG1388@2|Bacteria,1V8A5@1239|Firmicutes,4HIV2@91061|Bacilli,1ZG8Q@1386|Bacillus 91061|Bacilli M Lysin motif ypbE - - - - - - - - - - - LysM k141_12976_1 42565.FP66_12820 1.98e-68 212.0 COG4181@1|root,COG4181@2|Bacteria,1MXG9@1224|Proteobacteria,1RMG1@1236|Gammaproteobacteria,1XJAU@135619|Oceanospirillales 135619|Oceanospirillales Q ABC transporter - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_20037_1 1408424.JHYI01000011_gene1400 7.05e-49 168.0 COG0697@1|root,COG0697@2|Bacteria,1V23Q@1239|Firmicutes,4HDPS@91061|Bacilli,1ZEXG@1386|Bacillus 91061|Bacilli EG EamA-like transporter family - - - - - - - - - - - - EamA k141_35529_1 314287.GB2207_06708 5.8e-74 234.0 COG1975@1|root,COG1975@2|Bacteria,1MXKU@1224|Proteobacteria,1RQRT@1236|Gammaproteobacteria,1J9YN@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family - - - ko:K07402 - - - - ko00000 - - - XdhC_C,XdhC_CoxI k141_35529_2 1317118.ATO8_12056 1.53e-44 162.0 COG1216@1|root,COG1216@2|Bacteria,1NM61@1224|Proteobacteria,2TRZB@28211|Alphaproteobacteria,4KNJJ@93682|Roseivivax 28211|Alphaproteobacteria S Glycosyltransferase like family 2 - - - ko:K07011 - - - - ko00000 - - - Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_2 k141_35529_3 313612.L8106_17782 4.22e-31 119.0 COG1045@1|root,COG1045@2|Bacteria,1G2II@1117|Cyanobacteria,1H8WT@1150|Oscillatoriales 1117|Cyanobacteria E serine acetyltransferase - - 2.3.1.30 ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 M00021 R00586 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 - - - Hexapep k141_35529_4 927677.ALVU02000001_gene1586 4.13e-42 150.0 2DDZV@1|root,32U2A@2|Bacteria,1G7V6@1117|Cyanobacteria 1117|Cyanobacteria - - - - - - - - - - - - - - - k141_35529_5 1116369.KB890024_gene2033 5.09e-62 210.0 COG0438@1|root,COG0438@2|Bacteria,1P8MT@1224|Proteobacteria,2TRKC@28211|Alphaproteobacteria,43PX4@69277|Phyllobacteriaceae 28211|Alphaproteobacteria M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1 k141_30413_1 218284.CCDN010000002_gene2759 6.93e-95 283.0 COG0266@1|root,COG0266@2|Bacteria,1TP6F@1239|Firmicutes,4HBIU@91061|Bacilli,1ZCVD@1386|Bacillus 91061|Bacilli L Formamidopyrimidine-DNA glycosylase H2TH domain - - 4.2.99.18 ko:K05522 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Fapy_DNA_glyco,H2TH,zf-FPG_IleRS k141_30413_2 536227.CcarbDRAFT_0637 1.3e-12 69.7 COG0577@1|root,COG0577@2|Bacteria,1TPHU@1239|Firmicutes,247QW@186801|Clostridia,36VPE@31979|Clostridiaceae 186801|Clostridia V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX k141_1982_1 44251.PDUR_21255 9.49e-56 192.0 COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,4H9NW@91061|Bacilli,26TK1@186822|Paenibacillaceae 91061|Bacilli L DNA polymerase - - - - - - - - - - - - GIIM,RVT_1 k141_16366_2 1121921.KB898708_gene1460 4.35e-05 42.4 2DTZ7@1|root,33NAP@2|Bacteria,1NMA0@1224|Proteobacteria,1SGT2@1236|Gammaproteobacteria,2PP1Z@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_16366_3 565045.NOR51B_1758 3.84e-10 58.2 2CDU3@1|root,33AS4@2|Bacteria,1NGWQ@1224|Proteobacteria 1224|Proteobacteria S Protein of unknown function (DUF2970) - - - - - - - - - - - - DUF2970 k141_32963_1 1174504.AJTN02000251_gene3005 4.05e-57 189.0 COG0614@1|root,COG0614@2|Bacteria,1UNE3@1239|Firmicutes,4H9ZX@91061|Bacilli,1ZBS8@1386|Bacillus 91061|Bacilli P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component yvrC - - ko:K02016 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - Peripla_BP_2 k141_29441_1 218284.CCDN010000004_gene3104 2.44e-220 615.0 COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,4H9SB@91061|Bacilli,1ZBAN@1386|Bacillus 91061|Bacilli S COG1253 Hemolysins and related proteins containing CBS domains yhdP - - - - - - - - - - - CBS,CorC_HlyC,DUF21 k141_17433_3 981383.AEWH01000035_gene850 1.77e-30 110.0 COG0099@1|root,COG0099@2|Bacteria,1V3JH@1239|Firmicutes,4HGX6@91061|Bacilli 91061|Bacilli J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits rpsM GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02952 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S13 k141_34261_2 1453501.JELR01000001_gene3084 1.51e-66 208.0 COG1934@1|root,COG1934@2|Bacteria,1N776@1224|Proteobacteria,1RPM7@1236|Gammaproteobacteria,467V4@72275|Alteromonadaceae 1236|Gammaproteobacteria S Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm lptA GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0009279,GO:0010876,GO:0015920,GO:0016020,GO:0017089,GO:0019867,GO:0030288,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0042597,GO:0042802,GO:0044462,GO:0044464,GO:0046836,GO:0051179,GO:0051234,GO:0071702,GO:0071944,GO:1901264 - ko:K09774 - - - - ko00000,ko02000 1.B.42.1 - iB21_1397.B21_03016,iECBD_1354.ECBD_0542,iECB_1328.ECB_03065,iECD_1391.ECD_03065 OstA k141_24773_2 665952.HMPREF1015_02801 2.5e-46 150.0 COG4466@1|root,COG4466@2|Bacteria,1VEQM@1239|Firmicutes,4HKF8@91061|Bacilli,1ZI19@1386|Bacillus 91061|Bacilli S protein conserved in bacteria veg - - - - - - - - - - - VEG k141_17827_2 674977.VMC_05610 9.59e-201 561.0 COG0609@1|root,COG0609@2|Bacteria,1MYYG@1224|Proteobacteria,1RRQ1@1236|Gammaproteobacteria,1Y2KX@135623|Vibrionales 135623|Vibrionales P FecCD transport family - - - ko:K02015 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - FecCD k141_17827_3 223926.28810055 6.34e-194 542.0 COG0609@1|root,COG0609@2|Bacteria,1MV9W@1224|Proteobacteria,1RR9X@1236|Gammaproteobacteria,1XVF1@135623|Vibrionales 135623|Vibrionales P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily - - - ko:K02015 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - FecCD k141_17827_4 674977.VMC_05590 4.25e-170 476.0 COG1120@1|root,COG1120@2|Bacteria,1MUNG@1224|Proteobacteria,1RRII@1236|Gammaproteobacteria,1XV5R@135623|Vibrionales 135623|Vibrionales HP ABC transporter, ATP-binding protein fecE - 3.6.3.34 ko:K02013 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 - - ABC_tran k141_17827_5 674977.VMC_05580 6.3e-295 823.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XVCZ@135623|Vibrionales 135623|Vibrionales NT methyl-accepting chemotaxis protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal,dCache_1 k141_17827_6 1116375.VEJY3_24016 2.02e-93 297.0 COG0612@1|root,COG0612@2|Bacteria,1RE46@1224|Proteobacteria,1T167@1236|Gammaproteobacteria,1XT9U@135623|Vibrionales 135623|Vibrionales S Belongs to the peptidase M16 family - - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C k141_15305_1 1385512.N784_16140 9.68e-09 55.8 COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1TP4F@1239|Firmicutes,4HBNA@91061|Bacilli,2YA26@289201|Pontibacillus 91061|Bacilli F Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate ribD GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0016070,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 1.1.1.193,3.5.4.26 ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 M00125 R03458,R03459 RC00204,RC00933 ko00000,ko00001,ko00002,ko01000 - - - RibD_C,dCMP_cyt_deam_1 k141_4726_1 1117647.M5M_06805 7.75e-26 112.0 COG1629@1|root,COG4206@1|root,COG1629@2|Bacteria,COG4206@2|Bacteria,1MX4K@1224|Proteobacteria,1RP6B@1236|Gammaproteobacteria,1J4RA@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec k141_8169_1 218284.CCDN010000001_gene1811 1.6e-54 180.0 COG2720@1|root,COG2720@2|Bacteria,1TSH8@1239|Firmicutes,4HCPD@91061|Bacilli,1ZBNK@1386|Bacillus 91061|Bacilli V vancomycin resistance protein yoaR - - - - - - - - - - - PG_binding_4,VanW k141_17828_1 1453501.JELR01000005_gene1546 3.09e-78 234.0 28H65@1|root,2Z7IN@2|Bacteria,1Q4IY@1224|Proteobacteria,1RZHE@1236|Gammaproteobacteria,46703@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - Phage_lambda_P k141_21337_1 218284.CCDN010000002_gene2386 1.65e-53 173.0 COG2102@1|root,COG2102@2|Bacteria,1UAKZ@1239|Firmicutes,4HDX8@91061|Bacilli,1ZS01@1386|Bacillus 91061|Bacilli S Diphthamide synthase - - - - - - - - - - - - Diphthami_syn_2 k141_33261_1 935837.JAEK01000006_gene4241 3.77e-149 431.0 COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli,1ZB5X@1386|Bacillus 91061|Bacilli G phosphotransferase system sacP GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563 2.7.1.211 ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 M00269 R00811 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.1,4.A.1.2.10,4.A.1.2.12,4.A.1.2.9 - iYO844.BSU38050 PTS_EIIB,PTS_EIIC k141_30632_1 932678.THERU_03585 2.37e-32 118.0 COG2847@1|root,COG2847@2|Bacteria,2G587@200783|Aquificae 200783|Aquificae S Copper chaperone PCu(A)C - - - ko:K09796 - - - - ko00000,ko03110 - - - PCuAC k141_2343_1 1042377.AFPJ01000035_gene2641 2.49e-113 342.0 COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,1SC2U@1236|Gammaproteobacteria,46A5A@72275|Alteromonadaceae 1236|Gammaproteobacteria T diguanylate cyclase ycdT GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0032879,GO:0042710,GO:0044010,GO:0044464,GO:0044764,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051270,GO:0051271,GO:0051704,GO:0052621,GO:0065007,GO:0071944,GO:0090605,GO:0090609 - - - - - - - - - - 7TMR-DISMED2,7TMR-DISM_7TM,GGDEF,MASE4 k141_36639_1 218284.CCDN010000007_gene4028 3.46e-21 85.9 COG0629@1|root,COG0629@2|Bacteria,1V797@1239|Firmicutes,4HJFJ@91061|Bacilli,1ZH3N@1386|Bacillus 91061|Bacilli L Single-stranded DNA-binding protein ssbB - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k141_30633_1 1294265.JCM21738_2018 2.41e-135 387.0 COG1189@1|root,COG1189@2|Bacteria,1TPE4@1239|Firmicutes,4HAPY@91061|Bacilli,1ZBDS@1386|Bacillus 91061|Bacilli J rRNA methylase rrmJ - 2.1.1.226,2.1.1.227 ko:K06442 - - - - ko00000,ko01000,ko03009 - - - FtsJ,S4 k141_8170_1 218284.CCDN010000002_gene2577 1.48e-80 250.0 COG4191@1|root,COG4191@2|Bacteria,1UZ9W@1239|Firmicutes,4HDK2@91061|Bacilli,1ZD85@1386|Bacillus 91061|Bacilli T Histidine kinase - - 2.7.13.3 ko:K07697 ko02020,map02020 M00485 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - 5TM-5TMR_LYT,HATPase_c,HisKA k141_2344_2 1279017.AQYJ01000022_gene2603 6.79e-82 257.0 COG0584@1|root,COG0584@2|Bacteria,1MVWZ@1224|Proteobacteria,1RRBP@1236|Gammaproteobacteria,464IE@72275|Alteromonadaceae 1236|Gammaproteobacteria C Glycerophosphoryl diester phosphodiesterase family glpQ GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0008081,GO:0008889,GO:0009279,GO:0016020,GO:0016787,GO:0016788,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0042578,GO:0042597,GO:0043167,GO:0043169,GO:0044462,GO:0044464,GO:0046872,GO:0071944 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - iECNA114_1301.ECNA114_2331,iECSF_1327.ECSF_2119 GDPD k141_4729_1 1294265.JCM21738_2603 1.45e-174 491.0 COG2896@1|root,COG2896@2|Bacteria,1TP89@1239|Firmicutes,4HAKQ@91061|Bacilli,1ZCD4@1386|Bacillus 91061|Bacilli H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate moaA - 4.1.99.22 ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09394 RC03420 ko00000,ko00001,ko01000 - - - Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM k141_15307_1 863365.XHC_4424 3.32e-12 68.2 COG1595@1|root,COG1595@2|Bacteria,1N6SV@1224|Proteobacteria,1S570@1236|Gammaproteobacteria,1X6UZ@135614|Xanthomonadales 135614|Xanthomonadales K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_31839_2 1348114.OM33_15675 1.45e-51 164.0 2E6RA@1|root,331BE@2|Bacteria,1NQ95@1224|Proteobacteria,1SIPC@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF2695) - - - - - - - - - - - - DUF2695 k141_31839_3 247633.GP2143_02914 3.88e-36 122.0 COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SWYS@1236|Gammaproteobacteria,1JB34@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria K Ribonuclease B OB domain - - - - - - - - - - - - CSD k141_31839_5 1280952.HJA_00985 3.8e-45 153.0 COG1247@1|root,COG1247@2|Bacteria,1RGU8@1224|Proteobacteria,2UAVJ@28211|Alphaproteobacteria,4411I@69657|Hyphomonadaceae 28211|Alphaproteobacteria M COG1247 Sortase and related acyltransferases - - 2.3.1.183 ko:K03823 ko00440,ko01130,map00440,map01130 - R08871,R08938 RC00004,RC00064 ko00000,ko00001,ko01000 - - - Acetyltransf_4 k141_31839_7 746697.Aeqsu_1530 1.72e-91 275.0 COG0428@1|root,COG0428@2|Bacteria,4NHR7@976|Bacteroidetes,1HZWS@117743|Flavobacteriia 976|Bacteroidetes P transporter - - - ko:K07238 - - - - ko00000,ko02000 2.A.5.5 - - - k141_30718_1 218284.CCDN010000001_gene85 3.97e-153 440.0 COG0771@1|root,COG0771@2|Bacteria,1TQ3P@1239|Firmicutes,4HA5P@91061|Bacilli,1ZARV@1386|Bacillus 91061|Bacilli M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) murD - 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase_C,Mur_ligase_M k141_36734_1 1453501.JELR01000002_gene676 8.25e-86 256.0 COG0262@1|root,COG0262@2|Bacteria,1RH0P@1224|Proteobacteria,1S5VH@1236|Gammaproteobacteria,4678W@72275|Alteromonadaceae 1236|Gammaproteobacteria H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis folA GO:0000166,GO:0003674,GO:0003824,GO:0004146,GO:0005488,GO:0005542,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008144,GO:0008150,GO:0008152,GO:0016491,GO:0016645,GO:0016646,GO:0019842,GO:0031406,GO:0033218,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050661,GO:0050662,GO:0050896,GO:0051870,GO:0051871,GO:0055114,GO:0070401,GO:0070402,GO:0072341,GO:0097159,GO:1901265,GO:1901363 1.5.1.3 ko:K00287,ko:K18590 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 M00126,M00840 R00936,R00937,R00939,R00940,R02235,R02236,R11765 RC00109,RC00110,RC00158 br01600,ko00000,ko00001,ko00002,ko01000,ko01504 - - iECBD_1354.ECBD_3567,iECDH1ME8569_1439.ECDH1ME8569_0047,iECNA114_1301.ECNA114_0036,iEcDH1_1363.EcDH1_3551,iEcSMS35_1347.EcSMS35_0050,iG2583_1286.G2583_0050,iJN746.PP_5132,iNRG857_1313.NRG857_00250,iUMN146_1321.UM146_23020 DHFR_1 k141_36734_4 1279017.AQYJ01000028_gene2178 7.66e-107 319.0 COG3332@1|root,COG3332@2|Bacteria,1RDBS@1224|Proteobacteria,1S43Y@1236|Gammaproteobacteria,466QH@72275|Alteromonadaceae 1236|Gammaproteobacteria S Transport and Golgi organisation 2 - - - - - - - - - - - - TANGO2 k141_36734_5 1453501.JELR01000002_gene680 1.06e-315 878.0 COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,1RQR7@1236|Gammaproteobacteria,4668G@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria ycbB GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0006508,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0008236,GO:0008238,GO:0009273,GO:0009987,GO:0016740,GO:0016746,GO:0016755,GO:0016787,GO:0016807,GO:0017171,GO:0019538,GO:0033554,GO:0042546,GO:0043164,GO:0043170,GO:0044036,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0050896,GO:0051716,GO:0070004,GO:0070008,GO:0070011,GO:0071554,GO:0071704,GO:0071840,GO:0071972,GO:0140096,GO:1901564 - ko:K21470 - - - - ko00000,ko01002,ko01011 - - - PG_binding_1,YkuD k141_36734_6 1279017.AQYJ01000028_gene2175 1.1e-183 524.0 COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,1RQR7@1236|Gammaproteobacteria,4668G@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria ycbB GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0006508,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0008236,GO:0008238,GO:0009273,GO:0009987,GO:0016740,GO:0016746,GO:0016755,GO:0016787,GO:0016807,GO:0017171,GO:0019538,GO:0033554,GO:0042546,GO:0043164,GO:0043170,GO:0044036,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0050896,GO:0051716,GO:0070004,GO:0070008,GO:0070011,GO:0071554,GO:0071704,GO:0071840,GO:0071972,GO:0140096,GO:1901564 - ko:K21470 - - - - ko00000,ko01002,ko01011 - - - PG_binding_1,YkuD k141_36734_7 1453501.JELR01000002_gene682 3.46e-97 300.0 COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,1RQR7@1236|Gammaproteobacteria,4668G@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria ycbB GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0006508,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0008236,GO:0008238,GO:0009273,GO:0009987,GO:0016740,GO:0016746,GO:0016755,GO:0016787,GO:0016807,GO:0017171,GO:0019538,GO:0033554,GO:0042546,GO:0043164,GO:0043170,GO:0044036,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0050896,GO:0051716,GO:0070004,GO:0070008,GO:0070011,GO:0071554,GO:0071704,GO:0071840,GO:0071972,GO:0140096,GO:1901564 - ko:K21470 - - - - ko00000,ko01002,ko01011 - - - PG_binding_1,YkuD k141_37993_1 768066.HELO_3742 9.67e-117 344.0 COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,1RN1G@1236|Gammaproteobacteria,1XHQ7@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the aspartokinase family lysC - 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,ACT,ACT_7 k141_31840_1 218284.CCDN010000005_gene3295 2e-87 261.0 COG4116@1|root,COG4116@2|Bacteria,1VA56@1239|Firmicutes,4HMNE@91061|Bacilli,1ZH0U@1386|Bacillus 91061|Bacilli S protein conserved in bacteria yjbK - - - - - - - - - - - CYTH k141_31840_2 218284.CCDN010000005_gene3294 1.15e-18 82.8 COG0741@1|root,COG0741@2|Bacteria,1V6DD@1239|Firmicutes,4HIWA@91061|Bacilli,1ZH33@1386|Bacillus 91061|Bacilli M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) yjbJ - - - - - - - - - - - SLT k141_28484_2 305900.GV64_17230 4.59e-60 190.0 COG0563@1|root,COG0563@2|Bacteria,1REQW@1224|Proteobacteria,1S67T@1236|Gammaproteobacteria,1XK1D@135619|Oceanospirillales 135619|Oceanospirillales F COG0563 Adenylate kinase and related kinases - - - - - - - - - - - - AAA_18 k141_15366_1 218284.CCDN010000001_gene84 7.15e-181 508.0 COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,4HAEV@91061|Bacilli,1ZBY5@1386|Bacillus 91061|Bacilli D Belongs to the SEDS family spoVE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03588 ko04112,map04112 - - - ko00000,ko00001,ko02000,ko03036 2.A.103.1 - - FTSW_RODA_SPOVE k141_37994_1 1169144.KB910924_gene339 3.35e-114 343.0 COG4626@1|root,COG4626@2|Bacteria,1TPU1@1239|Firmicutes,4HAXI@91061|Bacilli,1ZE32@1386|Bacillus 91061|Bacilli S Terminase - - - - - - - - - - - - Terminase_1 k141_37995_1 1294265.JCM21738_13 5.74e-105 305.0 COG0494@1|root,COG0494@2|Bacteria,1V6F5@1239|Firmicutes,4HII9@91061|Bacilli,1ZFIW@1386|Bacillus 91061|Bacilli L Belongs to the Nudix hydrolase family nudF - 3.6.1.13 ko:K01515 ko00230,map00230 - R01054 RC00002 ko00000,ko00001,ko01000 - - iSB619.SA_RS07540,iYO844.BSU23610 NUDIX k141_30722_1 525904.Tter_1188 2.24e-92 292.0 COG0620@1|root,COG0620@2|Bacteria,2NPAE@2323|unclassified Bacteria 2|Bacteria E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation metE GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0040007,GO:0042084,GO:0042085,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050667,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_1,Meth_synt_2 k141_8247_2 622312.ROSEINA2194_01264 9.08e-62 195.0 COG0270@1|root,COG0270@2|Bacteria,1VSZI@1239|Firmicutes,24YBG@186801|Clostridia 186801|Clostridia L C-5 cytosine-specific DNA methylase - - - - - - - - - - - - DNA_methylase k141_31843_1 1150626.PHAMO_210222 0.000653 42.7 COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,2TQP0@28211|Alphaproteobacteria,2JQ4Z@204441|Rhodospirillales 204441|Rhodospirillales P Belongs to the ABC transporter superfamily - - - ko:K13896 ko02010,map02010 M00349 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.21,3.A.1.5.24 - - ABC_tran,oligo_HPY k141_31843_2 574375.BAGA_22115 2.29e-102 303.0 COG1124@1|root,COG1124@2|Bacteria,1V1R3@1239|Firmicutes,4HGUN@91061|Bacilli 91061|Bacilli EP abc transporter atp-binding protein - - 3.6.3.24 ko:K10824 ko02010,map02010 M00440 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.5 - - ABC_tran k141_37997_1 218284.CCDN010000007_gene3857 8.64e-48 154.0 COG4842@1|root,COG4842@2|Bacteria,1VACX@1239|Firmicutes,4HKCR@91061|Bacilli,1ZH2G@1386|Bacillus 91061|Bacilli S Belongs to the WXG100 family esxA - - - - - - - - - - - WXG100 k141_37997_2 218284.CCDN010000007_gene3858 3.49e-31 110.0 COG5417@1|root,COG5417@2|Bacteria,1VG9I@1239|Firmicutes,4HPXH@91061|Bacilli,1ZHKG@1386|Bacillus 91061|Bacilli S WXG100 protein secretion system (Wss), protein YukD yukD - - - - - - - - - - - YukD k141_30724_1 1033810.HLPCO_002510 4.62e-60 191.0 COG1863@1|root,COG1863@2|Bacteria 2|Bacteria P multisubunit Na H antiporter MnhE subunit - - - ko:K05569 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - MNHE k141_15368_1 1121935.AQXX01000053_gene2944 7.71e-05 45.4 COG2128@1|root,COG2128@2|Bacteria,1N82C@1224|Proteobacteria,1RQQI@1236|Gammaproteobacteria,1XINZ@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF3179) - - - - - - - - - - - - DUF3179 k141_15368_2 518766.Rmar_0283 2.67e-35 139.0 COG2067@1|root,COG2067@2|Bacteria,4NWE8@976|Bacteroidetes 976|Bacteroidetes I long-chain fatty acid transport protein - - - - - - - - - - - - PorP_SprF k141_8250_2 279010.BL00978 1.72e-31 117.0 29A6A@1|root,2ZX7B@2|Bacteria,1V4X8@1239|Firmicutes,4HJHK@91061|Bacilli,1ZGI9@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF4355) - - - - - - - - - - - - DUF4355 k141_37998_1 1117647.M5M_04610 6.52e-64 205.0 COG0811@1|root,COG0811@2|Bacteria,1NXZ9@1224|Proteobacteria,1S154@1236|Gammaproteobacteria,1J4YC@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria U COG0811 Biopolymer transport proteins - - - - - - - - - - - - MotA_ExbB k141_30725_1 218284.CCDN010000001_gene1867 2.11e-239 666.0 COG3845@1|root,COG3845@2|Bacteria,1UYQA@1239|Firmicutes,4HVSH@91061|Bacilli,1ZS12@1386|Bacillus 91061|Bacilli S ABC transporter, ATP-binding protein yufO - 3.6.3.17 ko:K02056 - M00221 - - ko00000,ko00002,ko01000,ko02000 3.A.1.2 - - ABC_tran k141_15369_1 1121456.ATVA01000013_gene1064 9.65e-35 127.0 COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,42R5H@68525|delta/epsilon subdivisions,2WNZS@28221|Deltaproteobacteria,2MC3Y@213115|Desulfovibrionales 28221|Deltaproteobacteria M Belongs to the ompA family pal - - ko:K03640 - - - - ko00000,ko02000 2.C.1.2 - - OmpA k141_28486_1 1453501.JELR01000002_gene331 1.13e-145 416.0 COG0730@1|root,COG0730@2|Bacteria,1R3V4@1224|Proteobacteria,1RVNC@1236|Gammaproteobacteria,4677I@72275|Alteromonadaceae 1236|Gammaproteobacteria S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE k141_28486_3 1453501.JELR01000001_gene3136 3.32e-191 541.0 COG3317@1|root,COG3317@2|Bacteria,1N670@1224|Proteobacteria,1RZVF@1236|Gammaproteobacteria,46CQH@72275|Alteromonadaceae 1236|Gammaproteobacteria M NlpB/DapX lipoprotein bamC - - ko:K07287 - - - - ko00000,ko02000 1.B.33.1 - - Lipoprotein_18 k141_30726_1 218284.CCDN010000002_gene2488 2.04e-142 408.0 COG0119@1|root,COG0119@2|Bacteria,1TS0A@1239|Firmicutes,4HAXZ@91061|Bacilli,1ZARP@1386|Bacillus 91061|Bacilli E Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds dmpG - 4.1.3.39 ko:K01666 ko00360,ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00360,map00362,map00621,map00622,map01100,map01120,map01220 M00545,M00569 R00750 RC00307,RC00371 br01602,ko00000,ko00001,ko00002,ko01000 - - - DmpG_comm,HMGL-like k141_28487_1 218284.CCDN010000002_gene2303 7.37e-128 369.0 COG1028@1|root,COG1028@2|Bacteria,1TRFB@1239|Firmicutes,4HBF8@91061|Bacilli,1ZB9T@1386|Bacillus 91061|Bacilli IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - - - - - - - - - - adh_short,adh_short_C2 k141_15371_1 1249627.D779_2770 1.12e-45 161.0 COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,1RMP9@1236|Gammaproteobacteria,1WW0V@135613|Chromatiales 135613|Chromatiales M lipoprotein releasing system, transmembrane protein, LolC E family - - - ko:K09808 ko02010,map02010 M00255 - - ko00000,ko00001,ko00002,ko02000 3.A.1.125 - - FtsX,MacB_PCD k141_38005_1 997296.PB1_07062 1.31e-08 55.1 COG0084@1|root,COG0084@2|Bacteria,1TNY1@1239|Firmicutes,4HA74@91061|Bacilli,1ZB78@1386|Bacillus 91061|Bacilli L hydrolase, TatD tatD GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase k141_38005_2 1294265.JCM21738_4349 3.13e-161 459.0 COG3583@1|root,COG3584@1|root,COG3583@2|Bacteria,COG3584@2|Bacteria,1TTIK@1239|Firmicutes,4HC79@91061|Bacilli,1ZC0Q@1386|Bacillus 91061|Bacilli T protein conserved in bacteria yabE - - - - - - - - - - - 3D,DUF348,G5 k141_15372_1 1294265.JCM21738_3508 7.56e-98 295.0 COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,4HA70@91061|Bacilli,1ZCE3@1386|Bacillus 91061|Bacilli F Belongs to the GARS family purD - 6.3.4.13 ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144 RC00090,RC00166 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS05245,iYO844.BSU06530 GARS_A,GARS_C,GARS_N k141_31851_1 469378.Ccur_13070 2.16e-10 62.0 COG1430@1|root,COG1430@2|Bacteria,2HVHD@201174|Actinobacteria,4CWUS@84998|Coriobacteriia 84998|Coriobacteriia S Uncharacterized ACR, COG1430 - - - ko:K09005 - - - - ko00000 - - - DUF192 k141_31851_2 1210884.HG799465_gene12231 7.96e-58 192.0 COG2064@1|root,COG2064@2|Bacteria,2IYG1@203682|Planctomycetes 203682|Planctomycetes NU Secretion system protein - - - ko:K12511 - - - - ko00000,ko02044 - - - T2SSF k141_28489_1 1238184.CM001792_gene295 3.69e-15 72.0 COG0494@1|root,COG0494@2|Bacteria,1UIXS@1239|Firmicutes,4ISW4@91061|Bacilli,23NIH@182709|Oceanobacillus 91061|Bacilli L NUDIX domain - - - - - - - - - - - - NUDIX k141_8256_1 218284.CCDN010000002_gene2931 3.79e-48 164.0 COG1194@1|root,COG1194@2|Bacteria,1TPUT@1239|Firmicutes,4H9UM@91061|Bacilli,1ZD5Y@1386|Bacillus 91061|Bacilli L A G-specific mutY - - ko:K03575 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD,NUDIX_4 k141_30729_1 218284.CCDN010000011_gene4419 5.44e-160 459.0 COG1488@1|root,COG1488@2|Bacteria,1TPDW@1239|Firmicutes,4HAI4@91061|Bacilli,1ZCGY@1386|Bacillus 91061|Bacilli H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP pncB - 6.3.4.21 ko:K00763 ko00760,ko01100,map00760,map01100 - R01724 RC00033 ko00000,ko00001,ko01000 - - iYO844.BSU31750 NAPRTase k141_15373_2 1279017.AQYJ01000027_gene1610 1.22e-22 95.9 COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,1RN6I@1236|Gammaproteobacteria,4654G@72275|Alteromonadaceae 1236|Gammaproteobacteria H Involved in the biosynthesis of porphyrin-containing compound yggW GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - - - - - - - - - - HemN_C,Radical_SAM k141_31852_1 1453501.JELR01000002_gene66 4.18e-83 253.0 COG1385@1|root,COG1385@2|Bacteria,1MZBG@1224|Proteobacteria,1S0HM@1236|Gammaproteobacteria,464CI@72275|Alteromonadaceae 1236|Gammaproteobacteria J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit - - - - - - - - - - - - Methyltrans_RNA k141_15374_1 218284.CCDN010000002_gene2215 5.31e-63 199.0 2BE93@1|root,32804@2|Bacteria,1UAWI@1239|Firmicutes,4IM9C@91061|Bacilli,1ZJIH@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_38009_1 218284.CCDN010000002_gene1995 5.35e-109 330.0 COG1001@1|root,COG1001@2|Bacteria,1TP84@1239|Firmicutes,4HAIR@91061|Bacilli,1ZAY2@1386|Bacillus 91061|Bacilli F adenine deaminase yerA GO:0003674,GO:0003824,GO:0006040,GO:0006044,GO:0006046,GO:0008150,GO:0008152,GO:0008448,GO:0009056,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0046348,GO:0071704,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901575 3.5.4.2 ko:K01486 ko00230,ko01100,map00230,map01100 - R01244 RC00477 ko00000,ko00001,ko01000 - - - Adenine_deam_C,Amidohydro_1 k141_28492_2 424947.U5N0I9_9CAUD 1.72e-08 59.3 4QAIU@10239|Viruses,4QUQC@35237|dsDNA viruses no RNA stage,4QPDE@28883|Caudovirales 28883|Caudovirales S HNH endonuclease - - - - - - - - - - - - - k141_31853_1 1423321.AS29_06155 2.34e-86 259.0 COG4122@1|root,COG4122@2|Bacteria,1V4A3@1239|Firmicutes,4HBCN@91061|Bacilli,1ZB6I@1386|Bacillus 91061|Bacilli S O-methyltransferase mdmC1 - - - - - - - - - - - Methyltransf_3 k141_31853_2 218284.CCDN010000002_gene2325 1.46e-71 221.0 COG0702@1|root,COG0702@2|Bacteria,1TQFS@1239|Firmicutes,4HDA2@91061|Bacilli,1ZBH3@1386|Bacillus 91061|Bacilli GM NmrA-like family yhfK GO:0005575,GO:0005622,GO:0005623,GO:0044464 - - - - - - - - - - NAD_binding_10 k141_38010_2 218284.CCDN010000001_gene1902 0.000626 41.2 COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,4H9N5@91061|Bacilli,1ZAYU@1386|Bacillus 91061|Bacilli J Belongs to the universal ribosomal protein uS2 family rpsB GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02967 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S2 k141_38012_1 406124.ACPC01000009_gene1483 8.3e-77 230.0 COG0346@1|root,COG0346@2|Bacteria,1V42J@1239|Firmicutes,4HHHX@91061|Bacilli,1ZHNW@1386|Bacillus 91061|Bacilli E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - Glyoxalase k141_31855_1 574375.BAGA_18825 9.73e-87 278.0 COG4926@1|root,COG4926@2|Bacteria,1TQHW@1239|Firmicutes,4HFA8@91061|Bacilli,1ZPV9@1386|Bacillus 91061|Bacilli S Prophage endopeptidase tail - - - - - - - - - - - - Prophage_tail k141_8257_1 469371.Tbis_0836 4.91e-54 181.0 COG2843@1|root,COG2843@2|Bacteria,2GK15@201174|Actinobacteria,4DYHG@85010|Pseudonocardiales 201174|Actinobacteria M enzyme of poly-gamma-glutamate biosynthesis (Capsule formation) - - - ko:K07282 - - - - ko00000 - - - PGA_cap k141_8257_2 1453501.JELR01000002_gene792 4.69e-206 574.0 COG1087@1|root,COG1087@2|Bacteria,1MUHI@1224|Proteobacteria,1RMTU@1236|Gammaproteobacteria,464WV@72275|Alteromonadaceae 1236|Gammaproteobacteria M UDP-glucose 4-epimerase galE - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase,GDP_Man_Dehyd k141_8257_3 1279017.AQYJ01000020_gene1251 1.44e-80 261.0 COG2766@1|root,COG2766@2|Bacteria,1MVW7@1224|Proteobacteria,1RNFJ@1236|Gammaproteobacteria,463Z0@72275|Alteromonadaceae 1236|Gammaproteobacteria T PrkA family serine protein kinase yeaG GO:0003674,GO:0003824,GO:0004672,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006995,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0042594,GO:0043170,GO:0043412,GO:0043562,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0140096,GO:1901564 - ko:K07180 - - - - ko00000 - - - AAA_PrkA,PrkA k141_28494_1 1042377.AFPJ01000051_gene110 9.65e-24 98.2 COG0598@1|root,COG0598@2|Bacteria,1MWMP@1224|Proteobacteria,1RNDQ@1236|Gammaproteobacteria,465JG@72275|Alteromonadaceae 1236|Gammaproteobacteria P Mediates influx of magnesium ions corA GO:0000041,GO:0003674,GO:0005215,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0008150,GO:0008324,GO:0015075,GO:0015087,GO:0015095,GO:0015099,GO:0015318,GO:0015675,GO:0015693,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0035444,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:1903830 - ko:K03284 - - - - ko00000,ko02000 1.A.35.1,1.A.35.3 - iYL1228.KPN_04313 CorA k141_32019_1 218284.CCDN010000005_gene3349 8.53e-110 329.0 COG4108@1|root,COG4108@2|Bacteria,1TPYT@1239|Firmicutes,4HADS@91061|Bacilli,1ZBIP@1386|Bacillus 91061|Bacilli J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP prfC GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02837 - - - - ko00000,ko03012 - - - GTP_EFTU,GTP_EFTU_D2,RF3_C k141_30854_1 472759.Nhal_1348 1.21e-20 95.5 COG1858@1|root,COG1858@2|Bacteria,1RC4D@1224|Proteobacteria,1SJKT@1236|Gammaproteobacteria 1236|Gammaproteobacteria C cytochrome C peroxidase - - - - - - - - - - - - - k141_30855_1 1122194.AUHU01000008_gene3400 3.22e-66 212.0 COG1082@1|root,COG1082@2|Bacteria,1RB2C@1224|Proteobacteria,1S292@1236|Gammaproteobacteria,466F9@72275|Alteromonadaceae 1236|Gammaproteobacteria G Xylose isomerase-like TIM barrel - - - - - - - - - - - - AP_endonuc_2 k141_30856_1 574375.BAGA_15840 2e-52 171.0 COG1670@1|root,COG1670@2|Bacteria,1V2C6@1239|Firmicutes,4HG3C@91061|Bacilli,1ZINV@1386|Bacillus 91061|Bacilli J Acetyltransferase (GNAT) domain p20 - 2.3.1.128 ko:K03790 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 k141_30856_2 66692.ABC0248 6.06e-36 132.0 COG1680@1|root,COG1680@2|Bacteria,1TYVU@1239|Firmicutes,4HE5K@91061|Bacilli,1ZCMW@1386|Bacillus 91061|Bacilli V Beta-lactamase - - - - - - - - - - - - Beta-lactamase k141_8599_4 1116375.VEJY3_20156 1.55e-208 579.0 COG1609@1|root,COG1609@2|Bacteria,1MXQ1@1224|Proteobacteria,1RNR1@1236|Gammaproteobacteria,1XT6Y@135623|Vibrionales 135623|Vibrionales K COG1609 Transcriptional regulators fruR - - ko:K03435 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_1,Peripla_BP_4 k141_8599_5 1116375.VEJY3_20151 3.14e-192 537.0 COG2374@1|root,COG2374@2|Bacteria,1PEFQ@1224|Proteobacteria,1RZZ9@1236|Gammaproteobacteria,1XU7K@135623|Vibrionales 135623|Vibrionales L Endonuclease/Exonuclease/phosphatase family - - - - - - - - - - - - Exo_endo_phos k141_8599_6 674977.VMC_21730 3.78e-39 135.0 COG2501@1|root,COG2501@2|Bacteria,1N8C4@1224|Proteobacteria,1SCIR@1236|Gammaproteobacteria,1XY0I@135623|Vibrionales 135623|Vibrionales S S4 domain - - - ko:K14761 - - - - ko00000,ko03009 - - - S4_2 k141_372_1 218284.CCDN010000001_gene591 2.51e-137 396.0 COG1219@1|root,COG1219@2|Bacteria,1TQ00@1239|Firmicutes,4H9U4@91061|Bacilli,1ZANE@1386|Bacillus 91061|Bacilli O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP clpX GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - ko:K03544 ko04112,map04112 - - - ko00000,ko00001,ko03110 - - - AAA_2,ClpB_D2-small,zf-C4_ClpX k141_26563_1 218284.CCDN010000001_gene641 1.12e-35 130.0 COG1104@1|root,COG1104@2|Bacteria,1TPYU@1239|Firmicutes,4HA5J@91061|Bacilli,1ZCRY@1386|Bacillus 91061|Bacilli E Cysteine desulfurase nifS - 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - - Aminotran_5 k141_26563_2 218284.CCDN010000001_gene642 9.69e-25 102.0 COG0029@1|root,COG0029@2|Bacteria,1UHSP@1239|Firmicutes,4H9ZZ@91061|Bacilli,1ZBIE@1386|Bacillus 91061|Bacilli H Catalyzes the oxidation of L-aspartate to iminoaspartate nadB - 1.4.3.16 ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 M00115 R00357,R00481 RC00006,RC02566 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C k141_5000_1 218284.CCDN010000008_gene4180 1.71e-78 243.0 COG0477@1|root,COG2814@2|Bacteria,1TPJ6@1239|Firmicutes,4HAGJ@91061|Bacilli,1ZBPE@1386|Bacillus 91061|Bacilli EGP Major facilitator superfamily yttB - - - - - - - - - - - MFS_1 k141_22886_1 1294265.JCM21738_4962 1.11e-105 318.0 COG0665@1|root,COG0723@1|root,COG0665@2|Bacteria,COG0723@2|Bacteria,1TR1R@1239|Firmicutes,4H9V8@91061|Bacilli,1ZC19@1386|Bacillus 91061|Bacilli CE COG0665 Glycine D-amino acid oxidases (deaminating) yhfW GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0044424,GO:0044464,GO:0055114 - - - - - - - - - - DAO,Rieske k141_16950_1 1378168.N510_02005 3.96e-08 57.4 COG0235@1|root,COG0235@2|Bacteria,1TS5G@1239|Firmicutes 1239|Firmicutes G Aldolase - - 4.1.2.17 ko:K01628 ko00051,ko01120,map00051,map01120 - R02262 RC00603,RC00604 ko00000,ko00001,ko01000 - - - Aldolase_II k141_16950_2 443254.Marpi_1095 3.06e-09 56.2 COG0268@1|root,COG0268@2|Bacteria,2GDFA@200918|Thermotogae 200918|Thermotogae J Binds directly to 16S ribosomal RNA rpsT - - ko:K02968 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S20p k141_15746_1 218284.CCDN010000008_gene4238 7.77e-87 257.0 COG0315@1|root,COG0315@2|Bacteria,1V3J4@1239|Firmicutes,4HH39@91061|Bacilli,1ZFIK@1386|Bacillus 91061|Bacilli H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) moaC - 4.6.1.17 ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R11372 RC03425 ko00000,ko00001,ko01000 - - - MoaC k141_25249_2 218284.CCDN010000003_gene2994 8.11e-66 200.0 2E3ZZ@1|root,32YWW@2|Bacteria,1VEIW@1239|Firmicutes,4HPDE@91061|Bacilli,1ZGYU@1386|Bacillus 91061|Bacilli S Sporulation protein YabP yabP GO:0005575,GO:0005623,GO:0042601,GO:0042763,GO:0044464 - - - - - - - - - - YabP k141_12234_1 240302.BN982_00768 5.05e-65 218.0 COG0726@1|root,COG0726@2|Bacteria,1V6DN@1239|Firmicutes,4HEPH@91061|Bacilli,3NG8D@45667|Halobacillus 91061|Bacilli G Polysaccharide deacetylase - - 3.5.1.104 ko:K22278 - - - - ko00000,ko01000 - - - DUF3298,DUF4163,Polysacc_deac_1 k141_6333_1 997296.PB1_01530 7.06e-124 362.0 COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,4H9WZ@91061|Bacilli,1ZC2F@1386|Bacillus 91061|Bacilli D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity ftsZ GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030428,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03531 ko04112,map04112 - - - ko00000,ko00001,ko02048,ko03036,ko04812 - - - FtsZ_C,Tubulin k141_37058_1 935837.JAEK01000006_gene4242 5.32e-208 585.0 COG1621@1|root,COG1621@2|Bacteria,1TPAE@1239|Firmicutes,4H9Y7@91061|Bacilli,1ZCBA@1386|Bacillus 91061|Bacilli G invertase sacA - 3.2.1.26 ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00801,R00802,R02410,R03635,R03921,R06088 RC00028,RC00077 ko00000,ko00001,ko01000 - GH32 iYO844.BSU38040 Glyco_hydro_32C,Glyco_hydro_32N k141_37058_2 491915.Aflv_2784 1.48e-10 61.2 COG0524@1|root,COG0524@2|Bacteria,1TPGM@1239|Firmicutes,4HD0H@91061|Bacilli,21WY2@150247|Anoxybacillus 91061|Bacilli G pfkB family carbohydrate kinase - - 2.7.1.4 ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 - R00760,R00867,R03920 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB k141_2674_1 316275.VSAL_I1253 0.0 914.0 COG2936@1|root,COG2936@2|Bacteria,1MVA8@1224|Proteobacteria,1TBNS@1236|Gammaproteobacteria,1Y16K@135623|Vibrionales 135623|Vibrionales S X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain - - - ko:K06978 - - - - ko00000 - - - PepX_C,Peptidase_S15 k141_2674_2 1005395.CSV86_25836 1.21e-13 77.8 COG0583@1|root,COG0583@2|Bacteria,1QFR1@1224|Proteobacteria,1RMND@1236|Gammaproteobacteria,1YVGQ@136845|Pseudomonas putida group 1236|Gammaproteobacteria K Transcriptional regulator trpI - - - - - - - - - - - HTH_1,LysR_substrate k141_2674_3 1453500.AT05_00795 1.72e-20 92.4 COG2197@1|root,COG2197@2|Bacteria,4NM2A@976|Bacteroidetes,1I0B0@117743|Flavobacteriia 976|Bacteroidetes KT Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - - - - - - - - - - GerE,Response_reg k141_2674_4 1187848.AJYQ01000150_gene2222 6.62e-81 241.0 COG0454@1|root,COG0456@2|Bacteria,1N6QA@1224|Proteobacteria,1S9WZ@1236|Gammaproteobacteria,1XXMG@135623|Vibrionales 135623|Vibrionales K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1 k141_2674_5 1116375.VEJY3_06550 0.0 1085.0 COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,1RNB7@1236|Gammaproteobacteria,1XTUF@135623|Vibrionales 135623|Vibrionales S metal-dependent hydrolase with the TIM-barrel fold - - - - - - - - - - - - Amidohydro_3 k141_2674_6 338969.Rfer_0709 7.01e-58 199.0 28JAH@1|root,2Z95A@2|Bacteria,1MXKT@1224|Proteobacteria,2VI69@28216|Betaproteobacteria,4AHBT@80864|Comamonadaceae 28216|Betaproteobacteria S Uncharacterised nucleotidyltransferase - - - - - - - - - - - - NTP_transf_5 k141_2674_7 864051.BurJ1DRAFT_3198 9.52e-64 210.0 COG5265@1|root,COG5265@2|Bacteria,1MWU5@1224|Proteobacteria,2VHDB@28216|Betaproteobacteria 28216|Betaproteobacteria O HPr kinase - - - - - - - - - - - - - k141_373_1 218284.CCDN010000007_gene3940 8.39e-112 331.0 COG1078@1|root,COG1078@2|Bacteria,1TPVB@1239|Firmicutes,4HAX8@91061|Bacilli,1ZBRB@1386|Bacillus 91061|Bacilli S COG1078 HD superfamily phosphohydrolases ywfO GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 - ko:K06885 - - - - ko00000 - - - HD k141_3884_2 1196031.ALEG01000039_gene1183 0.000488 41.2 2A0JV@1|root,30NQ2@2|Bacteria,1TWUS@1239|Firmicutes,4HS9X@91061|Bacilli,1ZJXW@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3813) - - - - - - - - - - - - DUF3813 k141_32272_2 1280001.BAOA01000060_gene2319 2.95e-10 56.2 2B6WY@1|root,31ZWT@2|Bacteria,1QKM1@1224|Proteobacteria,1TIRF@1236|Gammaproteobacteria,1XZIA@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_32272_3 1116375.VEJY3_04835 0.0 943.0 COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,1RMD2@1236|Gammaproteobacteria,1XU4R@135623|Vibrionales 135623|Vibrionales C Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - 1.1.99.1 ko:K00108 ko00260,ko01100,map00260,map01100 M00555 R01025 RC00087 ko00000,ko00001,ko00002,ko01000 - - - GMC_oxred_C,GMC_oxred_N k141_32272_5 1280001.BAOA01000060_gene2322 1.48e-291 803.0 COG1012@1|root,COG1012@2|Bacteria,1MVGW@1224|Proteobacteria,1RN53@1236|Gammaproteobacteria,1XSQ0@135623|Vibrionales 135623|Vibrionales C Belongs to the aldehyde dehydrogenase family - - 1.2.1.68 ko:K00154 - - - - ko00000,ko01000 - - - Aldedh k141_25250_1 218284.CCDN010000002_gene2278 1.3e-57 186.0 COG1131@1|root,COG1131@2|Bacteria,1TPMQ@1239|Firmicutes,4HA8K@91061|Bacilli,1ZAYW@1386|Bacillus 91061|Bacilli V COG1131 ABC-type multidrug transport system, ATPase component - - - ko:K01990,ko:K11050 ko02010,map02010 M00254,M00298 - - ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.130 - - ABC_tran k141_5001_1 1294265.JCM21738_2394 2.01e-157 447.0 2BZRV@1|root,2Z8AV@2|Bacteria,1UX40@1239|Firmicutes,4HAVP@91061|Bacilli,1ZDM4@1386|Bacillus 91061|Bacilli S Nuclease-related domain - - - - - - - - - - - - NERD k141_28861_1 1453501.JELR01000001_gene2731 5.57e-54 186.0 COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,1RMPG@1236|Gammaproteobacteria,464P1@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG0514 Superfamily II DNA helicase recQ - 3.6.4.12 ko:K03654 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind k141_26564_1 1116375.VEJY3_20126 5.96e-156 439.0 COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,1RMX1@1236|Gammaproteobacteria,1XUM1@135623|Vibrionales 135623|Vibrionales E COG1126 ABC-type polar amino acid transport system, ATPase component glnQ - 3.6.3.21 ko:K02028 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran k141_12235_1 985665.HPL003_26725 2.9e-45 157.0 COG1063@1|root,COG1063@2|Bacteria,1TPWP@1239|Firmicutes,4HABC@91061|Bacilli,26S36@186822|Paenibacillaceae 91061|Bacilli E Dehydrogenase ydjL GO:0000721,GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0055114 1.1.1.14,1.1.1.264,1.1.1.303,1.1.1.4 ko:K00004,ko:K00008,ko:K00098 ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100 M00014 R00875,R01896,R02855,R02946,R05684,R10504 RC00085,RC00089,RC00102,RC00205,RC00525 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU06240 ADH_N,ADH_zinc_N k141_27549_1 1294265.JCM21738_3389 1.12e-186 523.0 COG3320@1|root,COG3320@2|Bacteria,1TQPW@1239|Firmicutes,4HAFC@91061|Bacilli,1ZCU0@1386|Bacillus 91061|Bacilli Q Male sterility protein - - - - - - - - - - - - NAD_binding_4 k141_27549_2 1294265.JCM21738_3390 1.06e-45 159.0 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4HB97@91061|Bacilli,1ZBGZ@1386|Bacillus 91061|Bacilli C Belongs to the aldehyde dehydrogenase family - - 1.2.99.10 ko:K22445 - - - - ko00000,ko01000 - - - Aldedh k141_34743_1 46429.BV95_03424 5.85e-41 151.0 COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,2TRSS@28211|Alphaproteobacteria,2K0VG@204457|Sphingomonadales 28211|Alphaproteobacteria C The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) - - 1.2.4.4 ko:K11381 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 M00036 R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00027,RC00627,RC02743,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh,Transket_pyr,Transketolase_C k141_16951_1 1116375.VEJY3_23591 3.28e-209 597.0 COG1289@1|root,COG1289@2|Bacteria,1QJEM@1224|Proteobacteria,1SMXK@1236|Gammaproteobacteria,1XUKV@135623|Vibrionales 135623|Vibrionales S Aromatic acid exporter family member 1 VPA1578 - - - - - - - - - - - FUSC k141_19275_1 1279017.AQYJ01000022_gene2582 1.27e-46 156.0 COG1846@1|root,COG1846@2|Bacteria,1RH1F@1224|Proteobacteria,1S8WM@1236|Gammaproteobacteria,468SH@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG1846 Transcriptional regulators - - - - - - - - - - - - MarR k141_3886_1 1042377.AFPJ01000030_gene460 3.85e-43 160.0 COG5373@1|root,COG5373@2|Bacteria,1N08V@1224|Proteobacteria,1RTF0@1236|Gammaproteobacteria,46626@72275|Alteromonadaceae 1236|Gammaproteobacteria S Predicted membrane protein (DUF2339) - - - - - - - - - - - - DUF2339 k141_8600_1 1042377.AFPJ01000036_gene1147 1.91e-177 504.0 COG4299@1|root,COG4299@2|Bacteria,1R5FB@1224|Proteobacteria,1S1E0@1236|Gammaproteobacteria,467VN@72275|Alteromonadaceae 1236|Gammaproteobacteria S COGs COG4299 conserved - - - - - - - - - - - - DUF1624,DUF5009 k141_8600_2 1042377.AFPJ01000036_gene1146 2.57e-51 178.0 COG2173@1|root,COG3876@1|root,COG2173@2|Bacteria,COG3876@2|Bacteria,1MX3S@1224|Proteobacteria,1RSA3@1236|Gammaproteobacteria,465YH@72275|Alteromonadaceae 1236|Gammaproteobacteria M protein conserved in bacteria - - - - - - - - - - - - DUF1343 k141_25251_1 42565.FP66_13640 1.37e-50 164.0 COG0625@1|root,COG0625@2|Bacteria,1RA4Y@1224|Proteobacteria,1S2I8@1236|Gammaproteobacteria,1XJ5Z@135619|Oceanospirillales 135619|Oceanospirillales O Maleylacetoacetate isomerase - - 5.2.1.4 ko:K01801 ko00350,ko01100,ko01120,map00350,map01100,map01120 - R03868 RC00867 ko00000,ko00001,ko01000 - - - GST_C_2,GST_C_3,GST_N,GST_N_3 k141_25251_2 42565.FP66_13645 3.71e-41 142.0 COG0583@1|root,COG0583@2|Bacteria,1MXXA@1224|Proteobacteria,1RREE@1236|Gammaproteobacteria,1XKAP@135619|Oceanospirillales 135619|Oceanospirillales K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate k141_13404_1 218284.CCDN010000006_gene3643 2.77e-60 189.0 COG0040@1|root,COG0040@2|Bacteria,1TSVZ@1239|Firmicutes,4H9MH@91061|Bacilli,1ZCFW@1386|Bacillus 91061|Bacilli E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity hisG GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002,ko01000 - - - HisG,tRNA-synt_His k141_13404_2 218284.CCDN010000006_gene3644 5.7e-104 311.0 COG3705@1|root,COG3705@2|Bacteria,1TPZZ@1239|Firmicutes,4HBBA@91061|Bacilli,1ZB4H@1386|Bacillus 91061|Bacilli E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine hisZ - - ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002 - - - tRNA-synt_His k141_2676_1 223926.28808057 5.55e-82 245.0 COG0663@1|root,COG0663@2|Bacteria,1RD76@1224|Proteobacteria,1RPB6@1236|Gammaproteobacteria,1XU2T@135623|Vibrionales 135623|Vibrionales S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily yrdA - - - - - - - - - - - Hexapep k141_3887_1 1042377.AFPJ01000052_gene1588 5.13e-109 338.0 COG1629@1|root,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria,4651V@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec k141_21695_1 1279017.AQYJ01000028_gene2314 1.17e-126 379.0 COG0471@1|root,COG3273@1|root,COG0471@2|Bacteria,COG3273@2|Bacteria,1MU0K@1224|Proteobacteria,1RMI1@1236|Gammaproteobacteria,465YV@72275|Alteromonadaceae 1236|Gammaproteobacteria P Sodium:sulfate symporter transmembrane region - - - - - - - - - - - - CitMHS,Na_sulph_symp,TrkA_C k141_21695_3 1279017.AQYJ01000028_gene2316 2.21e-81 244.0 2EDU6@1|root,337PD@2|Bacteria,1NDWF@1224|Proteobacteria,1SFTJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_21695_4 1121878.AUGL01000006_gene522 2.43e-40 142.0 COG0406@1|root,COG0406@2|Bacteria,1N92W@1224|Proteobacteria,1SCJF@1236|Gammaproteobacteria 1236|Gammaproteobacteria G PFAM Phosphoglycerate mutase - - - - - - - - - - - - His_Phos_1 k141_18165_2 218284.CCDN010000010_gene4395 3.01e-148 425.0 COG3869@1|root,COG3869@2|Bacteria,1TPBA@1239|Firmicutes,4HC6U@91061|Bacilli,1ZBJU@1386|Bacillus 91061|Bacilli E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity mcsB GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 ko:K19405 - - R11090 RC00002,RC00203 ko00000,ko01000 - - - ATP-gua_Ptrans k141_12237_1 218284.CCDN010000001_gene1575 2.86e-92 277.0 COG0516@1|root,COG0516@2|Bacteria,1TNYF@1239|Firmicutes,4HA55@91061|Bacilli,1ZCDA@1386|Bacillus 91061|Bacilli F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides guaC - 1.7.1.7 ko:K00364 ko00230,map00230 - R01134 RC00457 ko00000,ko00001,ko01000 - - iSB619.SA_RS06660 IMPDH k141_26565_1 218284.CCDN010000004_gene3150 9.79e-67 214.0 COG0189@1|root,COG0189@2|Bacteria,1UZ79@1239|Firmicutes,4HTI1@91061|Bacilli,1ZBQZ@1386|Bacillus 91061|Bacilli HJ COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase) - - - - - - - - - - - - ATPgrasp_YheCD k141_26565_2 218284.CCDN010000004_gene3149 1e-81 243.0 COG1633@1|root,COG1633@2|Bacteria,1V7ZE@1239|Firmicutes,4IRN1@91061|Bacilli 91061|Bacilli S Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - - - - - - - - - - Ferritin,Rubrerythrin k141_1417_1 314345.SPV1_00345 9.02e-259 749.0 COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria 1224|Proteobacteria P ATPase, P-type transporting, HAD superfamily, subfamily IC - - 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3 k141_22889_3 1305836.AXVE01000002_gene3183 3.88e-25 96.3 2E3WD@1|root,32YTI@2|Bacteria,1VGKG@1239|Firmicutes,4HPQT@91061|Bacilli,26G1M@186818|Planococcaceae 91061|Bacilli S Family of unknown function (DUF5342) - - - - - - - - - - - - DUF5342 k141_34745_1 1453501.JELR01000001_gene2961 1.84e-107 325.0 COG0204@1|root,COG3176@1|root,COG0204@2|Bacteria,COG3176@2|Bacteria,1MWIM@1224|Proteobacteria,1RQD4@1236|Gammaproteobacteria,464MD@72275|Alteromonadaceae 1236|Gammaproteobacteria I Acyltransferase - - - - - - - - - - - - Acetyltransf_5,Acyltransferase k141_35887_1 384765.SIAM614_24537 5.95e-18 90.1 COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,2TT3Z@28211|Alphaproteobacteria 28211|Alphaproteobacteria M COG0739 Membrane proteins related to metalloendopeptidases MA20_20375 - - - - - - - - - - - Peptidase_M23 k141_22890_1 218284.CCDN010000002_gene2270 5.56e-114 338.0 COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,4HA6M@91061|Bacilli,1ZD4Q@1386|Bacillus 91061|Bacilli J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family rumA_1 - 2.1.1.190,2.1.1.35 ko:K00557,ko:K03215 - - - - ko00000,ko01000,ko03009,ko03016 - - - TRAM,tRNA_U5-meth_tr k141_8618_1 666685.R2APBS1_3892 6.86e-63 207.0 COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,1RMSS@1236|Gammaproteobacteria,1X3FD@135614|Xanthomonadales 135614|Xanthomonadales L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_int_SAM_4,Phage_integrase k141_20427_1 1122194.AUHU01000004_gene1444 5.98e-144 424.0 COG0213@1|root,COG0213@2|Bacteria,1MV3H@1224|Proteobacteria,1RPTG@1236|Gammaproteobacteria,4661E@72275|Alteromonadaceae 1236|Gammaproteobacteria F The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis - - 2.4.2.4 ko:K00758 ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219 - R01570,R02484,R08222,R08230 RC00063 ko00000,ko00001,ko01000 - - - Glycos_trans_3N,Glycos_transf_3,PYNP_C k141_26599_1 35841.BT1A1_2904 3.51e-07 48.1 29S76@1|root,30DBP@2|Bacteria,1UB44@1239|Firmicutes,4IMGQ@91061|Bacilli,1ZK4E@1386|Bacillus 91061|Bacilli S Probable sporulation protein (Bac_small_yrzI) - - - - - - - - - - - - Bac_small_YrzI k141_25264_1 1042377.AFPJ01000007_gene1790 1.41e-145 434.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MWKN@1224|Proteobacteria,1T3IM@1236|Gammaproteobacteria,465P2@72275|Alteromonadaceae 1236|Gammaproteobacteria P TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_31231_1 1116375.VEJY3_17201 6.63e-41 138.0 COG3122@1|root,COG3122@2|Bacteria,1N15V@1224|Proteobacteria,1S5V0@1236|Gammaproteobacteria,1XTMW@135623|Vibrionales 135623|Vibrionales S nucleoprotein polynucleotide-associated enzyme yaiL - - ko:K09912 - - - - ko00000 - - - DUF2058 k141_1429_2 218284.CCDN010000008_gene4239 5.12e-96 283.0 COG1763@1|root,COG1763@2|Bacteria,1VFA0@1239|Firmicutes,4HNMQ@91061|Bacilli,1ZH3K@1386|Bacillus 91061|Bacilli H molybdopterin-guanine dinucleotide biosynthesis protein mobB - - ko:K03753 - - - - ko00000 - - - MobB k141_18187_1 1294265.JCM21738_513 1.29e-87 263.0 COG1741@1|root,COG1741@2|Bacteria,1TQDV@1239|Firmicutes,4HE4S@91061|Bacilli,1ZCIX@1386|Bacillus 91061|Bacilli S Belongs to the pirin family - - - ko:K06911 - - - - ko00000 - - - Pirin,Pirin_C k141_20428_1 42565.FP66_05430 2.88e-52 167.0 COG0369@1|root,COG0369@2|Bacteria,1QUX0@1224|Proteobacteria,1T24E@1236|Gammaproteobacteria,1XMC9@135619|Oceanospirillales 135619|Oceanospirillales P Nitric oxide synthase - - - - - - - - - - - - Flavodoxin_1 k141_20428_2 42565.FP66_05425 4.82e-27 99.0 2EH9I@1|root,33B1E@2|Bacteria,1NH43@1224|Proteobacteria,1SD9Y@1236|Gammaproteobacteria,1XMSU@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF2788) - - - - - - - - - - - - DUF2788 k141_14524_1 1121373.KB903665_gene3093 1.83e-73 232.0 COG2159@1|root,COG2159@2|Bacteria,4P1VU@976|Bacteroidetes 976|Bacteroidetes S Amidohydrolase - - - - - - - - - - - - Amidohydro_2 k141_14524_2 1279017.AQYJ01000025_gene679 6.48e-21 94.4 COG0596@1|root,COG0596@2|Bacteria,1R6KU@1224|Proteobacteria,1RNTQ@1236|Gammaproteobacteria,4692F@72275|Alteromonadaceae 1236|Gammaproteobacteria S TAP-like protein - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_4 k141_9772_1 1116375.VEJY3_20566 1.23e-66 202.0 COG3125@1|root,COG3125@2|Bacteria,1RHE5@1224|Proteobacteria,1S6KQ@1236|Gammaproteobacteria,1XY6P@135623|Vibrionales 135623|Vibrionales C Prokaryotic Cytochrome C oxidase subunit IV cyoD - - ko:K02300 ko00190,ko01100,map00190,map01100 M00417 - - ko00000,ko00001,ko00002 3.D.4.5 - - COX4_pro k141_9772_2 1116375.VEJY3_20571 1.21e-136 387.0 COG1845@1|root,COG1845@2|Bacteria,1MUCK@1224|Proteobacteria,1RN9D@1236|Gammaproteobacteria,1XVK1@135623|Vibrionales 135623|Vibrionales C oxidase, subunit cyoC - - ko:K02299 ko00190,ko01100,map00190,map01100 M00417 - - ko00000,ko00001,ko00002 3.D.4.5 - - COX3 k141_9772_3 1116375.VEJY3_20576 3.98e-248 694.0 COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,1RPC3@1236|Gammaproteobacteria,1XU9F@135623|Vibrionales 135623|Vibrionales C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B cyoB - 1.10.3.10 ko:K02298 ko00190,ko01100,map00190,map01100 M00417 R11335 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.5 - - COX1 k141_32296_1 218284.CCDN010000001_gene206 3.64e-78 246.0 COG1721@1|root,COG1721@2|Bacteria,1U0JI@1239|Firmicutes,4HDNW@91061|Bacilli,1ZDIV@1386|Bacillus 91061|Bacilli S Protein of unknown function DUF58 - - - - - - - - - - - - DUF58 k141_26601_1 1461580.CCAS010000010_gene1440 8.95e-112 328.0 COG0715@1|root,COG0715@2|Bacteria,1TQN5@1239|Firmicutes,4HAB9@91061|Bacilli,1ZC0Z@1386|Bacillus 91061|Bacilli P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components ytlA GO:0003674,GO:0005215 - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1,NMT1_2 k141_16973_1 198467.NP92_13695 9.53e-24 96.7 COG5662@1|root,COG5662@2|Bacteria,1V6C7@1239|Firmicutes,4HFTK@91061|Bacilli,21VMG@150247|Anoxybacillus 91061|Bacilli K Putative zinc-finger rsiW GO:0005575,GO:0016020 - - - - - - - - - - Bactofilin,zf-HC2 k141_2692_1 1196028.ALEF01000064_gene1163 8.61e-80 240.0 COG0693@1|root,COG0693@2|Bacteria,1V3I7@1239|Firmicutes,4HFNG@91061|Bacilli,4C5IA@84406|Virgibacillus 91061|Bacilli S DJ-1/PfpI family yfkM - 3.5.1.124 ko:K05520 - - - - ko00000,ko01000,ko01002 - - - DJ-1_PfpI k141_2692_2 218284.CCDN010000002_gene2232 9.33e-57 189.0 COG3486@1|root,COG3486@2|Bacteria,1UZAQ@1239|Firmicutes,4HBWJ@91061|Bacilli,1ZB3E@1386|Bacillus 91061|Bacilli Q L-lysine 6-monooxygenase (NADPH-requiring) - - 1.14.13.59 ko:K03897 ko00310,ko01120,map00310,map01120 - R00448 RC00298 ko00000,ko00001,ko01000 - - - K_oxygenase k141_6353_1 1128427.KB904821_gene1952 4.55e-39 142.0 COG0010@1|root,COG0010@2|Bacteria,1G1JZ@1117|Cyanobacteria,1H8PF@1150|Oscillatoriales 1117|Cyanobacteria E Belongs to the arginase family speB - 3.5.3.11 ko:K01480 ko00330,ko01100,map00330,map01100 M00133 R01157 RC00024,RC00329 ko00000,ko00001,ko00002,ko01000 - - - Arginase k141_24036_1 1121374.KB891589_gene86 1.26e-49 167.0 COG0179@1|root,COG0179@2|Bacteria,1MUPF@1224|Proteobacteria,1RPYA@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) - - - - - - - - - - - - DUF2437,FAA_hydrolase k141_12262_1 1453501.JELR01000005_gene1581 3.62e-68 229.0 COG2273@1|root,COG3488@1|root,COG2273@2|Bacteria,COG3488@2|Bacteria,1MXUW@1224|Proteobacteria,1RRXK@1236|Gammaproteobacteria,464KW@72275|Alteromonadaceae 1236|Gammaproteobacteria C Di-haem oxidoreductase, putative peroxidase - - - - - - - - - - - - CBM_6,DHOR,F5_F8_type_C,Glyco_hydro_16,Lipoprotein_15,TSP_3 k141_37073_1 1279017.AQYJ01000029_gene3807 1.94e-90 287.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RPM5@1236|Gammaproteobacteria,4657E@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1960 Acyl-CoA dehydrogenases fadE - 1.3.8.7 ko:K00249,ko:K06445 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,DUF1974 k141_37073_2 1453501.JELR01000001_gene2287 7.97e-84 269.0 COG0427@1|root,COG0427@2|Bacteria,1PJY0@1224|Proteobacteria,1RPS6@1236|Gammaproteobacteria,46523@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG0427 Acetyl-CoA hydrolase - - - - - - - - - - - - AcetylCoA_hyd_C k141_22910_1 1042377.AFPJ01000012_gene1359 1.08e-179 506.0 COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,1RP1T@1236|Gammaproteobacteria,464VA@72275|Alteromonadaceae 1236|Gammaproteobacteria J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus fmt GO:0003674,GO:0003824,GO:0004479,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006418,GO:0006431,GO:0006464,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019752,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 ko:K00604 ko00670,ko00970,map00670,map00970 - R03940 RC00026,RC00165 ko00000,ko00001,ko01000 - - iECABU_c1320.ECABU_c37050,iECUMN_1333.ECUMN_3761,ic_1306.c4048 Formyl_trans_C,Formyl_trans_N k141_37294_1 218284.CCDN010000001_gene31 5.28e-168 488.0 COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,4HAWN@91061|Bacilli,1ZC17@1386|Bacillus 91061|Bacilli L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) recG GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecG_wedge k141_33827_2 218284.CCDN010000001_gene1330 2.48e-43 156.0 COG0567@1|root,COG0567@2|Bacteria,1TRDW@1239|Firmicutes,4HAUI@91061|Bacilli,1ZAX3@1386|Bacillus 91061|Bacilli C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) odhA GO:0003674,GO:0003824,GO:0004591,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016624,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045333,GO:0055114,GO:0071704,GO:0072350,GO:1902494,GO:1990204,GO:1990234 1.2.4.2 ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R00621,R01933,R01940,R03316,R08549 RC00004,RC00027,RC00627,RC02743,RC02833,RC02883 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr k141_29026_1 42565.FP66_00510 4.7e-178 507.0 COG0388@1|root,COG0388@2|Bacteria,1MX4I@1224|Proteobacteria,1RP30@1236|Gammaproteobacteria,1XHBM@135619|Oceanospirillales 135619|Oceanospirillales M Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase yhcX - - - - - - - - - - - Acetyltransf_1,CN_hydrolase k141_18453_1 218284.CCDN010000008_gene4170 1.04e-84 260.0 COG0192@1|root,COG0192@2|Bacteria,1TPCV@1239|Firmicutes,4HB33@91061|Bacilli,1ZBHR@1386|Bacillus 91061|Bacilli H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme metK GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 M00034,M00035,M00368,M00609 R00177,R04771 RC00021,RC01211 ko00000,ko00001,ko00002,ko01000 - - - S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N k141_17127_1 218284.CCDN010000004_gene3157 1.71e-183 520.0 COG0635@1|root,COG0635@2|Bacteria,1TREM@1239|Firmicutes,4HC2D@91061|Bacilli,1ZCRB@1386|Bacillus 91061|Bacilli H coproporphyrinogen III oxidase hemZ - - - - - - - - - - - Radical_SAM k141_11305_1 42565.FP66_09060 4.7e-87 282.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1XH4Q@135619|Oceanospirillales 135619|Oceanospirillales V efflux pump - - - ko:K03296,ko:K18138 ko01501,ko01503,map01501,map01503 M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2 - - ACR_tran k141_15943_1 1453501.JELR01000002_gene1400 3.08e-38 135.0 COG0454@1|root,COG0456@2|Bacteria,1NGUX@1224|Proteobacteria,1SV6D@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Acetyltransferase (GNAT) family - - - - - - - - - - - - - k141_10146_1 1279017.AQYJ01000027_gene1655 8.24e-121 358.0 COG2223@1|root,COG2223@2|Bacteria,1MU27@1224|Proteobacteria,1RMUK@1236|Gammaproteobacteria,4640N@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG2223 Nitrate nitrite transporter narK - - ko:K02575 ko00910,map00910 M00615 - - ko00000,ko00001,ko00002,ko02000 2.A.1.8 - - MFS_1 k141_10146_2 1279017.AQYJ01000027_gene1654 8.29e-14 68.9 COG2197@1|root,COG2197@2|Bacteria,1NQH7@1224|Proteobacteria,1RNXI@1236|Gammaproteobacteria,465FY@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain narL - - ko:K07684 ko02020,map02020 M00471 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg k141_13769_1 406124.ACPC01000020_gene3786 1.08e-78 261.0 COG3459@1|root,COG3459@2|Bacteria,1TVMK@1239|Firmicutes,4H9ZP@91061|Bacilli,1ZF4F@1386|Bacillus 91061|Bacilli G Glycosyl hydrolase 36 superfamily, catalytic domain chvB1 - 2.4.1.20,2.4.1.333 ko:K00702,ko:K13688,ko:K21298 ko00500,ko01100,map00500,map01100 - R00952 RC00049 ko00000,ko00001,ko01000,ko01003 - GH94,GT36,GT84 - Glyco_hydro_36,Glyco_transf_36 k141_33828_1 1042377.AFPJ01000009_gene322 8.89e-83 270.0 COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,1RND3@1236|Gammaproteobacteria,4658W@72275|Alteromonadaceae 1236|Gammaproteobacteria E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor gcvP GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019464,GO:0019752,GO:0032991,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902494,GO:1990204 1.4.4.2 ko:K00281,ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko00002,ko01000 - - - GDC-P k141_21909_2 218284.CCDN010000008_gene4182 7.63e-133 389.0 COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,4HADT@91061|Bacilli,1ZAZA@1386|Bacillus 91061|Bacilli KT Transcriptional regulator - - - - - - - - - - - - HTH_8,PAS,PAS_9,Sigma54_activat k141_6514_1 1479235.KK366039_gene2990 3.32e-21 91.7 COG1131@1|root,COG1131@2|Bacteria,1RFGG@1224|Proteobacteria 1224|Proteobacteria V Pfam ABC transporter related - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_6514_2 1479235.KK366039_gene2991 5.22e-149 423.0 COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,1RMKY@1236|Gammaproteobacteria,1XHEV@135619|Oceanospirillales 135619|Oceanospirillales H Belongs to the FPP GGPP synthase family - - - - - - - - - - - - polyprenyl_synt k141_5366_1 743722.Sph21_0360 0.000456 43.1 COG2989@1|root,COG2989@2|Bacteria,4NH3J@976|Bacteroidetes,1IRD3@117747|Sphingobacteriia 976|Bacteroidetes S ErfK YbiS YcfS YnhG family protein - - - ko:K21470 - - - - ko00000,ko01002,ko01011 - - - PG_binding_1,YkuD k141_37296_1 1279017.AQYJ01000027_gene1591 2.03e-127 404.0 COG0643@1|root,COG0784@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,4650G@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0643 Chemotaxis protein histidine kinase and related kinases chpA - - ko:K02487,ko:K06596 ko02020,ko02025,map02020,map02025 M00507 - - ko00000,ko00001,ko00002,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg k141_17128_1 1034347.CAHJ01000032_gene4067 1.05e-79 251.0 COG1292@1|root,COG1292@2|Bacteria,1TRS6@1239|Firmicutes,4HA7U@91061|Bacilli,1ZBRN@1386|Bacillus 91061|Bacilli M Belongs to the BCCT transporter (TC 2.A.15) family opuD_3 - - - - - - - - - - - BCCT k141_670_1 218284.CCDN010000003_gene2969 8.31e-147 415.0 COG4123@1|root,COG4123@2|Bacteria,1TQ25@1239|Firmicutes,4HA8W@91061|Bacilli,1ZCBX@1386|Bacillus 91061|Bacilli S Conserved hypothetical protein 95 yabB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.223 ko:K07461,ko:K15460 - - - - ko00000,ko01000,ko03016 - - - GIY-YIG,MTS k141_2858_1 218284.CCDN010000002_gene1982 5.58e-93 274.0 COG0041@1|root,COG0041@2|Bacteria,1V1MV@1239|Firmicutes,4HFR7@91061|Bacilli,1ZFRE@1386|Bacillus 91061|Bacilli F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) purE - 5.4.99.18 ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07405 RC01947 ko00000,ko00001,ko00002,ko01000 - - - AIRC k141_2858_2 218284.CCDN010000002_gene1981 6.12e-30 107.0 2BXZ7@1|root,330R4@2|Bacteria,1VF1V@1239|Firmicutes,4HNQ7@91061|Bacilli,1ZR8R@1386|Bacillus 91061|Bacilli S NETI protein - - - - - - - - - - - - NETI k141_35027_1 1280001.BAOA01000052_gene1645 1.64e-74 230.0 COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,1RP1T@1236|Gammaproteobacteria,1XTX0@135623|Vibrionales 135623|Vibrionales J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus fmt GO:0003674,GO:0003824,GO:0004479,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006418,GO:0006431,GO:0006464,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019752,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 ko:K00604 ko00670,ko00970,map00670,map00970 - R03940 RC00026,RC00165 ko00000,ko00001,ko01000 - - - Formyl_trans_C,Formyl_trans_N k141_35027_2 223926.28808070 5.52e-301 822.0 COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1MWPE@1224|Proteobacteria,1RN8X@1236|Gammaproteobacteria,1XUH8@135623|Vibrionales 135623|Vibrionales J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA rsmB GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 ko:K03500 - - - - ko00000,ko01000,ko03009 - - - Methyltr_RsmB-F,NusB k141_35027_3 1116375.VEJY3_15335 0.0 867.0 COG0569@1|root,COG0569@2|Bacteria,1MW8R@1224|Proteobacteria,1RNVQ@1236|Gammaproteobacteria,1XTKZ@135623|Vibrionales 135623|Vibrionales P Potassium transporter peripheral membrane component trkA - - ko:K03499 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkA_C,TrkA_N k141_35027_4 1219076.N646_2144 7e-254 703.0 COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,1RMN6@1236|Gammaproteobacteria,1XUGG@135623|Vibrionales 135623|Vibrionales P Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA trkH-1 - - ko:K03498 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkH k141_20706_1 218284.CCDN010000001_gene1490 2.54e-170 492.0 COG0187@1|root,COG0187@2|Bacteria,1TQCF@1239|Firmicutes,4H9UC@91061|Bacilli,1ZBMM@1386|Bacillus 91061|Bacilli L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parE GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 - ko:K02622 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim k141_17129_1 1177154.Y5S_03237 7.44e-78 244.0 COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,1RN0E@1236|Gammaproteobacteria,1XJQS@135619|Oceanospirillales 135619|Oceanospirillales M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K13888 - M00709 - - ko00000,ko00002,ko02000 8.A.1 - - HlyD_D23 k141_11308_1 1294265.JCM21738_1468 2.4e-19 78.6 COG0451@1|root,COG0451@2|Bacteria 2|Bacteria GM ADP-glyceromanno-heptose 6-epimerase activity ltd - 4.2.1.45 ko:K01709 ko00520,map00520 - R02426 RC00402 ko00000,ko00001,ko01000 - - - Epimerase k141_11308_2 1294265.JCM21738_1469 1.7e-127 368.0 COG0709@1|root,COG0709@2|Bacteria,1TQCJ@1239|Firmicutes,4HB6P@91061|Bacilli,1ZCAH@1386|Bacillus 91061|Bacilli E Synthesizes selenophosphate from selenide and ATP selD - 2.7.9.3 ko:K01008 ko00450,ko01100,map00450,map01100 - R03595 RC00002,RC02878 ko00000,ko00001,ko01000,ko03016 - - - AIRS,AIRS_C k141_10147_1 314292.VAS14_21131 3.85e-184 540.0 COG1629@1|root,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria,1XV5Z@135623|Vibrionales 135623|Vibrionales HP TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_19582_1 1294265.JCM21738_4800 3.25e-73 229.0 COG5438@1|root,COG5438@2|Bacteria,1TPEV@1239|Firmicutes,4HCP3@91061|Bacilli,1ZBT8@1386|Bacillus 91061|Bacilli S YibE/F-like protein yibE - - - - - - - - - - - YibE_F k141_19582_2 1033734.CAET01000038_gene227 3.66e-57 187.0 COG5438@1|root,COG5438@2|Bacteria,1TSWX@1239|Firmicutes,4HBKX@91061|Bacilli,1ZC6A@1386|Bacillus 91061|Bacilli S YibE/F-like protein yibF - - - - - - - - - - - YibE_F k141_12604_2 218284.CCDN010000007_gene3873 1.07e-42 140.0 2CH76@1|root,3318K@2|Bacteria,1VGAH@1239|Firmicutes,4HP8U@91061|Bacilli,1ZI5T@1386|Bacillus 91061|Bacilli S Gas vesicle synthesis protein GvpO - - - - - - - - - - - - GvpO k141_672_1 1246484.D479_01535 1.68e-22 94.4 COG1984@1|root,COG1984@2|Bacteria,1TR6U@1239|Firmicutes,4HACC@91061|Bacilli,3NDUV@45667|Halobacillus 91061|Bacilli E Allophanate hydrolase subunit 2 kipA - - ko:K06350 - - - - ko00000 - - - CT_A_B k141_672_2 1246484.D479_01530 4.24e-55 178.0 COG2049@1|root,COG2049@2|Bacteria,1TTBZ@1239|Firmicutes,4HHJJ@91061|Bacilli,3NDBP@45667|Halobacillus 91061|Bacilli E Allophanate hydrolase subunit 1 kipI - - ko:K06351 - - - - ko00000 - - - CT_C_D k141_2859_1 1453501.JELR01000002_gene1534 6.67e-88 266.0 COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,1RNMX@1236|Gammaproteobacteria,464RI@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde argC GO:0003674,GO:0003824,GO:0003942,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.38 ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R03443 RC00684 ko00000,ko00001,ko00002,ko01000 - - iSSON_1240.SSON_4131 Semialdhyde_dh,Semialdhyde_dhC k141_6516_1 999547.KI421500_gene3067 5e-64 204.0 COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,2TQX2@28211|Alphaproteobacteria,281AA@191028|Leisingera 28211|Alphaproteobacteria E ABC transporter glnQ - 3.6.3.21 ko:K02028,ko:K09972 ko02010,map02010 M00232,M00236 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3,3.A.1.3.17,3.A.1.3.18,3.A.1.3.7,3.A.1.3.8 - - ABC_tran k141_21910_1 1347368.HG964404_gene5160 1.93e-32 125.0 COG2207@1|root,COG2207@2|Bacteria,1TQKE@1239|Firmicutes,4HAA2@91061|Bacilli,1ZD9Q@1386|Bacillus 91061|Bacilli K Transcriptional regulator ybfP GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009438,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019172,GO:0019243,GO:0019249,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046185,GO:0046394,GO:0051596,GO:0061727,GO:0071704,GO:0072330,GO:1901575,GO:1901576,GO:1901615,GO:1901617 - ko:K13653 - - - - ko00000,ko03000 - - - GyrI-like,HTH_18 k141_37297_1 1042377.AFPJ01000020_gene2056 6.29e-129 382.0 COG2067@1|root,COG2067@2|Bacteria,1R3SS@1224|Proteobacteria,1S0X2@1236|Gammaproteobacteria 1236|Gammaproteobacteria I long-chain fatty acid transport protein - - - ko:K06076 - - - - ko00000,ko02000 1.B.9 - - Toluene_X k141_20707_1 1294265.JCM21738_4963 7.26e-44 145.0 COG2606@1|root,COG2606@2|Bacteria,1V6JF@1239|Firmicutes,4HHFK@91061|Bacilli,1ZGGN@1386|Bacillus 91061|Bacilli S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily ebsC - - ko:K03976 - - - - ko00000,ko01000,ko03016 - - - tRNA_edit k141_20707_2 1382315.JPOI01000001_gene1048 3.23e-19 88.2 COG1004@1|root,COG1004@2|Bacteria,1TQFN@1239|Firmicutes,4HADP@91061|Bacilli,1WFWT@129337|Geobacillus 91061|Bacilli M Belongs to the UDP-glucose GDP-mannose dehydrogenase family - - 1.1.1.22 ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 M00014,M00129,M00361,M00362 R00286 RC00291 ko00000,ko00001,ko00002,ko01000 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N k141_35028_1 1294265.JCM21738_2546 7.98e-60 186.0 COG4990@1|root,COG4990@2|Bacteria,1UYFQ@1239|Firmicutes,4HE05@91061|Bacilli,1ZMPX@1386|Bacillus 91061|Bacilli S Peptidase_C39 like family - - - - - - - - - - - - Peptidase_C39_2 k141_35028_2 1294265.JCM21738_1492 5.16e-06 47.4 29TKG@1|root,30ETX@2|Bacteria,1UCYR@1239|Firmicutes,4IPEP@91061|Bacilli,1ZPTB@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_18455_1 674977.VMC_40850 1.35e-39 142.0 COG1249@1|root,COG1249@2|Bacteria,1MVVE@1224|Proteobacteria,1RMJT@1236|Gammaproteobacteria,1XSSW@135623|Vibrionales 135623|Vibrionales C Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation sthA GO:0003674,GO:0003824,GO:0003957,GO:0005215,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0008746,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0016491,GO:0016651,GO:0016652,GO:0022857,GO:0022890,GO:0034220,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.6.1.1 ko:K00322 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - Pyr_redox_2,Pyr_redox_dim k141_18455_2 223926.28807967 2.57e-137 390.0 COG1309@1|root,COG1309@2|Bacteria,1MUJ5@1224|Proteobacteria,1RN9W@1236|Gammaproteobacteria,1XUMQ@135623|Vibrionales 135623|Vibrionales K Transcriptional regulator fabR - - ko:K22105 - - - - ko00000,ko03000 - - - TetR_N k141_18455_3 1116375.VEJY3_14860 1.42e-75 226.0 2ARMX@1|root,31GYK@2|Bacteria,1RH5N@1224|Proteobacteria,1S68Y@1236|Gammaproteobacteria,1XXAD@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF1422) yijD - - - - - - - - - - - DUF1422 k141_23233_1 218284.CCDN010000001_gene1749 1.53e-92 299.0 COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1TPYV@1239|Firmicutes,4HBER@91061|Bacilli,1ZBGN@1386|Bacillus 91061|Bacilli E Methionine synthase metH - 2.1.1.13 ko:K00548 ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230 M00017 R00946,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans k141_23233_2 986075.CathTA2_1721 4.88e-25 104.0 COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,1TPYV@1239|Firmicutes,4HAB5@91061|Bacilli 91061|Bacilli E catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine yitJ - 1.5.1.20,2.1.1.10 ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 M00377 R00650,R01224,R07168 RC00003,RC00035,RC00081 ko00000,ko00001,ko00002,ko01000 - - - MTHFR,S-methyl_trans k141_37298_1 498211.CJA_3627 9.25e-79 260.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MV8W@1224|Proteobacteria,1RQEQ@1236|Gammaproteobacteria,1FGUN@10|Cellvibrio 1236|Gammaproteobacteria P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec k141_32491_2 1191299.AJYX01000064_gene3576 5.84e-115 336.0 COG3745@1|root,COG3745@2|Bacteria,1MW75@1224|Proteobacteria,1S6EP@1236|Gammaproteobacteria,1XT4T@135623|Vibrionales 135623|Vibrionales U COG3745 Flp pilus assembly protein CpaB VV2661 - - ko:K02279 - - - - ko00000,ko02035,ko02044 - - - RcpC,SAF k141_21911_1 218284.CCDN010000001_gene130 2.24e-114 333.0 COG0109@1|root,COG0109@2|Bacteria,1TPS1@1239|Firmicutes,4HBJT@91061|Bacilli,1ZCJT@1386|Bacillus 91061|Bacilli O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group ctaB GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 M00154 R07411 RC01786 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 - - iSB619.SA_RS05465 UbiA k141_8924_1 472759.Nhal_0806 1.18e-17 76.3 COG0073@1|root,COG0073@2|Bacteria,1RGU7@1224|Proteobacteria,1S6NH@1236|Gammaproteobacteria,1X12N@135613|Chromatiales 135613|Chromatiales J Putative tRNA binding domain - - - ko:K06878 - - - - ko00000 - - - tRNA_bind k141_8924_2 674977.VMC_27370 7.43e-121 350.0 COG0662@1|root,COG4977@1|root,COG0662@2|Bacteria,COG4977@2|Bacteria,1QUHI@1224|Proteobacteria,1S3BZ@1236|Gammaproteobacteria,1XW71@135623|Vibrionales 135623|Vibrionales K COG2207 AraC-type DNA-binding domain-containing proteins - - - - - - - - - - - - Cupin_2,HTH_18 k141_35029_1 1131730.BAVI_23368 5.88e-98 285.0 COG0735@1|root,COG0735@2|Bacteria,1V400@1239|Firmicutes,4HHF8@91061|Bacilli,1ZFKE@1386|Bacillus 91061|Bacilli P Belongs to the Fur family perR GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - ko:K09825 - - - - ko00000,ko03000 - - - FUR k141_25597_1 42565.FP66_07035 1.1e-97 306.0 COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,1RNW3@1236|Gammaproteobacteria,1XI9K@135619|Oceanospirillales 135619|Oceanospirillales L that it carries out the mismatch recognition step. This protein has a weak ATPase activity mutS - - ko:K03555 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V k141_19584_1 715226.ABI_33030 8.09e-18 85.1 COG0673@1|root,COG0673@2|Bacteria,1MU8F@1224|Proteobacteria,2U47H@28211|Alphaproteobacteria,2KHKM@204458|Caulobacterales 204458|Caulobacterales S Oxidoreductase domain protein - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C k141_20708_1 1453501.JELR01000002_gene929 1.93e-114 348.0 COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,1RM89@1236|Gammaproteobacteria,464TH@72275|Alteromonadaceae 1236|Gammaproteobacteria L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex mutL GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K03572 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - DNA_mis_repair,HATPase_c_3,MutL_C k141_10150_1 218284.CCDN010000002_gene2022 2.4e-63 195.0 COG3655@1|root,COG3655@2|Bacteria,1U3YV@1239|Firmicutes,4IDRG@91061|Bacilli,1ZJ2A@1386|Bacillus 91061|Bacilli K Cro/C1-type HTH DNA-binding domain - - - - - - - - - - - - HTH_26 k141_29028_1 1192034.CAP_1380 7.27e-29 118.0 COG0415@1|root,COG0415@2|Bacteria,1RG4D@1224|Proteobacteria,42NWP@68525|delta/epsilon subdivisions,2WJUA@28221|Deltaproteobacteria,2YUE6@29|Myxococcales 28221|Deltaproteobacteria L Deoxyribodipyrimidine photo-lyase phr - 4.1.99.3 ko:K01669 - - - - ko00000,ko01000,ko03400 - - - DNA_photolyase,FAD_binding_7 k141_14717_1 1116375.VEJY3_00795 1.99e-186 522.0 COG4239@1|root,COG4239@2|Bacteria,1MUM5@1224|Proteobacteria,1RNUH@1236|Gammaproteobacteria,1XT25@135623|Vibrionales 135623|Vibrionales P transport system permease component yejE - - ko:K13895 ko02010,map02010 M00349 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.21,3.A.1.5.24 - - BPD_transp_1 k141_14717_2 1280001.BAOA01000051_gene1484 9.49e-238 654.0 COG4174@1|root,COG4174@2|Bacteria,1MVKE@1224|Proteobacteria,1RMH8@1236|Gammaproteobacteria,1XT3P@135623|Vibrionales 135623|Vibrionales P transport system, permease component yejB - - ko:K13894 ko02010,map02010 M00349 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.21,3.A.1.5.24 - - BPD_transp_1 k141_14717_3 314292.VAS14_21131 3.02e-69 231.0 COG1629@1|root,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria,1XV5Z@135623|Vibrionales 135623|Vibrionales HP TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_32512_2 1294265.JCM21738_4572 9.42e-44 145.0 COG0590@1|root,COG0590@2|Bacteria,1V3HZ@1239|Firmicutes,4HH7S@91061|Bacilli,1ZFRP@1386|Bacillus 91061|Bacilli FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) tadA GO:0002097,GO:0002100,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 3.5.4.33 ko:K11991 - - R10223 RC00477 ko00000,ko01000,ko03016 - - - MafB19-deam k141_5390_1 218284.CCDN010000008_gene4214 5.37e-78 255.0 COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,4HA1S@91061|Bacilli,1ZAYY@1386|Bacillus 91061|Bacilli D Belongs to the FtsK SpoIIIE SftA family sftA - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_SpoIIIE,Ftsk_gamma k141_1648_2 1279017.AQYJ01000020_gene1214 0.0 1234.0 COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,1RNHV@1236|Gammaproteobacteria,46410@72275|Alteromonadaceae 1236|Gammaproteobacteria M Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) mrcB GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008289,GO:0008360,GO:0008658,GO:0008955,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031406,GO:0031975,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042277,GO:0042546,GO:0042597,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071723,GO:0071840,GO:0071944,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 2.4.1.129,3.4.16.4 ko:K05365 ko00550,map00550 - R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 iECIAI39_1322.ECIAI39_0153,iSBO_1134.SBO_0138,iSbBS512_1146.SbBS512_E0140,iYL1228.KPN_00164 PBP1_TM,Transgly,Transpeptidase,UB2H k141_1648_5 1056512.D515_03758 1e-83 251.0 COG1225@1|root,COG1225@2|Bacteria,1RA5K@1224|Proteobacteria,1S28Q@1236|Gammaproteobacteria,1XUIQ@135623|Vibrionales 135623|Vibrionales O AhpC/TSA family - - - - - - - - - - - - AhpC-TSA,Redoxin k141_1648_6 1042377.AFPJ01000032_gene2698 1.19e-201 563.0 COG0113@1|root,COG0113@2|Bacteria,1MWMW@1224|Proteobacteria,1RP6Q@1236|Gammaproteobacteria,464JJ@72275|Alteromonadaceae 1236|Gammaproteobacteria H Belongs to the ALAD family hemB - 4.2.1.24 ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00036 RC00918,RC01781 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ALAD k141_1648_7 1123257.AUFV01000006_gene374 2.39e-32 117.0 COG3686@1|root,COG3686@2|Bacteria,1MZP7@1224|Proteobacteria,1SADS@1236|Gammaproteobacteria,1X806@135614|Xanthomonadales 135614|Xanthomonadales S MAPEG family - - - - - - - - - - - - MAPEG k141_1648_8 1279017.AQYJ01000020_gene1210 6.87e-279 766.0 COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,1RM7N@1236|Gammaproteobacteria,463YV@72275|Alteromonadaceae 1236|Gammaproteobacteria H Glutamate-1-semialdehyde aminotransferase hemL GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016853,GO:0016866,GO:0016869,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042286,GO:0042440,GO:0042802,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 5.4.3.8 ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02272 RC00677 ko00000,ko00001,ko00002,ko01000,ko01007 - - iUMNK88_1353.UMNK88_158 Aminotran_3 k141_1648_10 1042377.AFPJ01000032_gene2695 1.53e-73 223.0 COG1981@1|root,COG1981@2|Bacteria,1RHGS@1224|Proteobacteria,1S5XY@1236|Gammaproteobacteria,467HW@72275|Alteromonadaceae 1236|Gammaproteobacteria S membrane - - - ko:K08973 - - - - ko00000 - - - UPF0093 k141_1648_11 1279017.AQYJ01000020_gene1207 2.21e-255 720.0 COG0038@1|root,COG0038@2|Bacteria,1MV4K@1224|Proteobacteria,1RQJW@1236|Gammaproteobacteria,465J9@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0038 Chloride channel protein EriC eriC - - ko:K03281 - - - - ko00000 2.A.49 - - Voltage_CLC k141_1648_12 1279017.AQYJ01000020_gene1206 1.29e-195 549.0 COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,1RNMX@1236|Gammaproteobacteria,464RI@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde argC GO:0003674,GO:0003824,GO:0003942,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.38 ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R03443 RC00684 ko00000,ko00001,ko00002,ko01000 - - iSSON_1240.SSON_4131 Semialdhyde_dh,Semialdhyde_dhC k141_1648_13 1279017.AQYJ01000020_gene1205 1.63e-119 347.0 2DA4I@1|root,32TUN@2|Bacteria,1N0WK@1224|Proteobacteria,1S6HI@1236|Gammaproteobacteria,467DY@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_1648_15 1453501.JELR01000002_gene1537 6.92e-75 224.0 COG0316@1|root,COG0316@2|Bacteria,1RHCW@1224|Proteobacteria,1S675@1236|Gammaproteobacteria,4677W@72275|Alteromonadaceae 1236|Gammaproteobacteria C Iron-sulfur cluster insertion protein ErpA erpA GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009061,GO:0009987,GO:0010467,GO:0015980,GO:0016043,GO:0016226,GO:0019538,GO:0022607,GO:0031163,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055114,GO:0071704,GO:0071840,GO:1901564 - ko:K15724 - - - - ko00000 - - - Fe-S_biosyn k141_1648_16 1279017.AQYJ01000020_gene1202 2.64e-210 587.0 COG2377@1|root,COG2377@2|Bacteria,1MV4E@1224|Proteobacteria,1RNTZ@1236|Gammaproteobacteria,464CU@72275|Alteromonadaceae 1236|Gammaproteobacteria O Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling anmK GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237 2.7.1.170 ko:K09001 - - - - ko00000,ko01000 - - iECABU_c1320.ECABU_c18930,iECED1_1282.ECED1_1841,ic_1306.c2032 AnmK k141_1648_17 1453501.JELR01000002_gene1539 3.89e-233 653.0 COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,1RM7S@1236|Gammaproteobacteria,4640S@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0739 Membrane proteins related to metalloendopeptidases yebA - - - - - - - - - - - OapA,OapA_N,Peptidase_M23 k141_1648_18 1279017.AQYJ01000020_gene1199 2.65e-275 757.0 COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,1RPKC@1236|Gammaproteobacteria,464H7@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) tyrS GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006437,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - iAF1260.b1637,iBWG_1329.BWG_1452,iECDH10B_1368.ECDH10B_1771,iECDH1ME8569_1439.ECDH1ME8569_1581,iECH74115_1262.ECH74115_2349,iECIAI39_1322.ECIAI39_1418,iECNA114_1301.ECNA114_1685,iECO103_1326.ECO103_1778,iECO111_1330.ECO111_2107,iECO26_1355.ECO26_2366,iECSE_1348.ECSE_1760,iECSF_1327.ECSF_1500,iECSP_1301.ECSP_2202,iECUMN_1333.ECUMN_1928,iECW_1372.ECW_m1805,iECs_1301.ECs2346,iEKO11_1354.EKO11_2137,iETEC_1333.ETEC_1672,iEcDH1_1363.EcDH1_2003,iEcE24377_1341.EcE24377A_1847,iEcHS_1320.EcHS_A1713,iEcSMS35_1347.EcSMS35_1562,iEcolC_1368.EcolC_1992,iJO1366.b1637,iSFV_1184.SFV_1654,iSF_1195.SF1662,iSSON_1240.SSON_1519,iSbBS512_1146.SbBS512_E1829,iUMNK88_1353.UMNK88_2097,iWFL_1372.ECW_m1805,iY75_1357.Y75_RS08585 S4,tRNA-synt_1b k141_14740_1 218284.CCDN010000002_gene2301 3.94e-30 114.0 COG1957@1|root,COG1957@2|Bacteria,1TSAR@1239|Firmicutes,4HDCS@91061|Bacilli,1ZD4R@1386|Bacillus 91061|Bacilli F nucleoside hydrolase - - 3.2.2.1 ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 - R01245,R01273,R01677,R01770,R02143 RC00033,RC00063,RC00122,RC00318,RC00485 ko00000,ko00001,ko01000 - - - IU_nuc_hydro k141_14740_2 1246484.D479_10841 3.79e-104 301.0 COG0346@1|root,COG0346@2|Bacteria,1UZ2H@1239|Firmicutes,4HEGA@91061|Bacilli,3ND3T@45667|Halobacillus 91061|Bacilli E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - Glyoxalase k141_36097_1 1196031.ALEG01000072_gene918 6.29e-81 253.0 COG0402@1|root,COG0402@2|Bacteria,1TS92@1239|Firmicutes,4HCCA@91061|Bacilli,1ZQP1@1386|Bacillus 91061|Bacilli F Amidohydrolase family - - - - - - - - - - - - Amidohydro_3 k141_10179_1 794846.AJQU01000142_gene153 1.52e-39 135.0 COG2963@1|root,COG2963@2|Bacteria,1RI5X@1224|Proteobacteria,2UBB0@28211|Alphaproteobacteria,4BHNS@82115|Rhizobiaceae 28211|Alphaproteobacteria L Transposase - - - ko:K07483 - - - - ko00000 - - - HTH_Tnp_1 k141_10179_2 1502724.FF80_01023 3.5e-109 323.0 COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,2U0FG@28211|Alphaproteobacteria 28211|Alphaproteobacteria L COG2801 Transposase and inactivated derivatives - - - ko:K07497 - - - - ko00000 - - - HTH_21,rve,rve_3 k141_21932_1 1254432.SCE1572_46515 2e-35 139.0 COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,1NPFY@1224|Proteobacteria,42PRW@68525|delta/epsilon subdivisions,2WIMG@28221|Deltaproteobacteria,2YYG9@29|Myxococcales 28221|Deltaproteobacteria H Methylenetetrahydrofolate reductase metF-2 - 1.5.1.20,2.1.1.10 ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 M00377 R00650,R01224,R07168 RC00003,RC00035,RC00081 ko00000,ko00001,ko00002,ko01000 - - iAF987.Gmet_0504 MTHFR,S-methyl_trans k141_11343_1 218284.CCDN010000006_gene3621 7.75e-29 115.0 COG0745@1|root,COG5000@1|root,COG5002@1|root,COG0745@2|Bacteria,COG5000@2|Bacteria,COG5002@2|Bacteria,1U7NI@1239|Firmicutes,4HA3E@91061|Bacilli,1ZCFX@1386|Bacillus 91061|Bacilli T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - GAF,GAF_3,HAMP,HATPase_c,HisKA,Response_reg k141_18482_1 1453501.JELR01000001_gene2104 2.81e-97 298.0 COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RP53@1236|Gammaproteobacteria,466MR@72275|Alteromonadaceae 1236|Gammaproteobacteria T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg k141_32513_2 1294265.JCM21738_1412 1.27e-30 115.0 COG0789@1|root,COG0789@2|Bacteria,1VKY9@1239|Firmicutes,4HYXJ@91061|Bacilli,1ZDXG@1386|Bacillus 91061|Bacilli K MerR HTH family regulatory protein - - - - - - - - - - - - MerR_1 k141_7616_1 42099.EPrPV00000022729 5.05e-29 109.0 COG2351@1|root,KOG3006@2759|Eukaryota,1MGYD@121069|Pythiales 121069|Pythiales I OHCU decarboxylase. Source PGD - - - - - - - - - - - - OHCU_decarbox k141_7616_2 1122603.ATVI01000005_gene3745 8.69e-05 43.9 COG2351@1|root,COG2351@2|Bacteria,1RH84@1224|Proteobacteria,1S9GA@1236|Gammaproteobacteria,1XC6K@135614|Xanthomonadales 135614|Xanthomonadales S HIUase/Transthyretin family - - 3.5.2.17 ko:K07127 ko00230,ko01100,ko01120,map00230,map01100,map01120 M00546 R06601 RC03393 ko00000,ko00001,ko00002,ko01000,ko02000 9.B.35.1.2,9.B.35.2 - - Transthyretin k141_30135_1 198467.NP92_01225 7.94e-27 102.0 COG0745@1|root,COG0745@2|Bacteria,1VAYR@1239|Firmicutes,4HKT2@91061|Bacilli,21X0D@150247|Anoxybacillus 91061|Bacilli KT cheY-homologous receiver domain - - - - - - - - - - - - Response_reg k141_37477_1 218284.CCDN010000002_gene2582 1.93e-84 266.0 COG0515@1|root,COG3173@1|root,COG0515@2|Bacteria,COG3173@2|Bacteria,1U4B2@1239|Firmicutes,4HG90@91061|Bacilli,1ZR5R@1386|Bacillus 91061|Bacilli KLT Phosphotransferase enzyme family - - 2.7.11.1 ko:K08884 - - - - ko00000,ko01000,ko01001 - - - APH k141_32743_1 177437.HRM2_28580 2.5e-22 97.8 COG1539@1|root,COG1539@2|Bacteria,1QVAP@1224|Proteobacteria,43BPU@68525|delta/epsilon subdivisions,2X712@28221|Deltaproteobacteria,2MPJW@213118|Desulfobacterales 28221|Deltaproteobacteria H Putative molybdenum carrier - - - - - - - - - - - - MoCo_carrier k141_7834_1 1279017.AQYJ01000028_gene2320 4.68e-105 325.0 COG0709@1|root,COG1252@1|root,COG0709@2|Bacteria,COG1252@2|Bacteria,1MWFG@1224|Proteobacteria,1RQ5Q@1236|Gammaproteobacteria,465WT@72275|Alteromonadaceae 1236|Gammaproteobacteria CE Belongs to the selenophosphate synthase 1 family. Class I subfamily - - 2.7.9.3 ko:K01008 ko00450,ko01100,map00450,map01100 - R03595 RC00002,RC02878 ko00000,ko00001,ko01000,ko03016 - - - AIRS,AIRS_C,Pyr_redox_2 k141_6767_1 243277.VC_0184 5.9e-309 847.0 COG0582@1|root,COG0582@2|Bacteria,1R5D1@1224|Proteobacteria,1S1EP@1236|Gammaproteobacteria,1XUYK@135623|Vibrionales 135623|Vibrionales L viral genome integration into host DNA - - - - - - - - - - - - - k141_6767_2 243277.VC_0185 6.5e-108 320.0 COG0582@1|root,COG0582@2|Bacteria,1R96H@1224|Proteobacteria,1RZPN@1236|Gammaproteobacteria,1XWU0@135623|Vibrionales 135623|Vibrionales L Phage integrase family - - - - - - - - - - - - Phage_integrase k141_5661_1 218284.CCDN010000001_gene41 5.63e-67 225.0 COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,4H9KD@91061|Bacilli,1ZBBU@1386|Bacillus 91061|Bacilli KLT serine threonine protein kinase prkC GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 ko:K08884,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PASTA,Pkinase k141_29266_1 1279017.AQYJ01000023_gene3160 1.05e-46 166.0 COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,1RPJB@1236|Gammaproteobacteria,466BN@72275|Alteromonadaceae 1236|Gammaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoN GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 ko:K00343 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_M k141_31446_1 218284.CCDN010000008_gene4032 1.4e-72 234.0 COG1785@1|root,COG1785@2|Bacteria,1TQCI@1239|Firmicutes,4HA27@91061|Bacilli,1ZB3J@1386|Bacillus 91061|Bacilli P Belongs to the alkaline phosphatase family phoB - 3.1.3.1 ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 M00126 R02135,R04620 RC00017 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 - - - Alk_phosphatase,Cu_amine_oxidN1 k141_23506_2 187944.H8YJB1_9CAUD 3.61e-74 245.0 4QGMJ@10239|Viruses,4QX02@35237|dsDNA viruses no RNA stage,4QSYG@28883|Caudovirales,4QM5B@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k141_36258_1 1122993.KB898329_gene1127 6.08e-11 66.2 COG1225@1|root,COG1225@2|Bacteria,4P08Q@976|Bacteroidetes,2FWN9@200643|Bacteroidia 976|Bacteroidetes O Antioxidant, AhpC TSA family - - - - - - - - - - - - AhpC-TSA,DUF4369,Thioredoxin_8 k141_3044_1 218284.CCDN010000001_gene725 3.89e-83 254.0 COG1466@1|root,COG1466@2|Bacteria,1TRM0@1239|Firmicutes,4HBB4@91061|Bacilli,1ZBST@1386|Bacillus 91061|Bacilli L DNA polymerase III delta subunit holA - 2.7.7.7 ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta k141_6768_1 314285.KT71_15009 1.21e-16 85.9 COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,1RNCU@1236|Gammaproteobacteria,1J8SY@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd GO:0000715,GO:0000716,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006283,GO:0006289,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008094,GO:0008150,GO:0008152,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0015616,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031326,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0043175,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051276,GO:0051716,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF k141_11612_1 1121940.AUDZ01000012_gene1058 2.34e-69 222.0 COG3287@1|root,COG3287@2|Bacteria,1MVUZ@1224|Proteobacteria,1RY7N@1236|Gammaproteobacteria,1XIZ8@135619|Oceanospirillales 135619|Oceanospirillales S FIST N domain - - - - - - - - - - - - FIST,FIST_C k141_32744_1 748449.Halha_1361 2.85e-07 57.0 COG0845@1|root,COG0845@2|Bacteria,1TT2M@1239|Firmicutes,24BJV@186801|Clostridia 186801|Clostridia M Efflux transporter, RND family, MFP subunit - - - ko:K02005,ko:K13888 - M00709 - - ko00000,ko00002,ko02000 8.A.1 - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 k141_30297_1 66692.ABC2840 7.2e-65 201.0 COG3728@1|root,COG3728@2|Bacteria,1VAD9@1239|Firmicutes,4HKES@91061|Bacilli,1ZHGN@1386|Bacillus 91061|Bacilli L Terminase small subunit - - - ko:K07474 - - - - ko00000 - - - Terminase_2 k141_34066_1 1453501.JELR01000002_gene891 1e-147 434.0 COG2831@1|root,COG2831@2|Bacteria,1MWEC@1224|Proteobacteria,1RYVX@1236|Gammaproteobacteria,466E3@72275|Alteromonadaceae 1236|Gammaproteobacteria U Haemolysin secretion/activation protein ShlB/FhaC/HecB - - - - - - - - - - - - POTRA_2,ShlB k141_7835_1 1434319.W5RVD4_9CAUD 1.25e-09 62.0 4QBHW@10239|Viruses,4QW8N@35237|dsDNA viruses no RNA stage,4QTT7@28883|Caudovirales,4QKR7@10699|Siphoviridae 10699|Siphoviridae S sequence-specific DNA binding transcription factor activity - - - - - - - - - - - - - k141_37478_2 1394176.AWUO01000005_gene498 9.86e-26 106.0 COG1929@1|root,COG1929@2|Bacteria,2GKHX@201174|Actinobacteria,4CZRH@85004|Bifidobacteriales 201174|Actinobacteria G Belongs to the glycerate kinase type-1 family glxK - 2.7.1.165 ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 - R08572 RC00002,RC00428 ko00000,ko00001,ko01000 - - - Gly_kinase k141_23507_2 218284.CCDN010000001_gene671 1.9e-98 297.0 COG0124@1|root,COG0124@2|Bacteria,1TP3D@1239|Firmicutes,4HAM2@91061|Bacilli,1ZBXR@1386|Bacillus 91061|Bacilli J histidyl-tRNA synthetase hisS - 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_2b,tRNA-synt_His k141_14096_1 42565.FP66_10620 7.53e-123 354.0 COG0688@1|root,COG0688@2|Bacteria,1MVT4@1224|Proteobacteria,1RN1U@1236|Gammaproteobacteria,1XICF@135619|Oceanospirillales 135619|Oceanospirillales I Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily psd - 4.1.1.65 ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 M00093 R02055 RC00299 ko00000,ko00001,ko00002,ko01000 - - - PS_Dcarbxylase k141_5662_1 1294265.JCM21738_4277 2.94e-71 221.0 COG2755@1|root,COG2755@2|Bacteria,1V2R0@1239|Firmicutes,4HI9B@91061|Bacilli,1ZFY5@1386|Bacillus 91061|Bacilli E GDSL-like Lipase/Acylhydrolase ypmR - - - - - - - - - - - Cu_amine_oxidN1,Lipase_GDSL_2 k141_6769_2 218284.CCDN010000007_gene4002 2.01e-82 244.0 COG0355@1|root,COG0355@2|Bacteria,1VA89@1239|Firmicutes,4HKHS@91061|Bacilli,1ZGET@1386|Bacillus 91061|Bacilli C Produces ATP from ADP in the presence of a proton gradient across the membrane atpC GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_DE,ATP-synt_DE_N k141_22170_1 1196031.ALEG01000028_gene4353 2.54e-60 196.0 COG0791@1|root,COG1388@1|root,COG0791@2|Bacteria,COG1388@2|Bacteria,1TP24@1239|Firmicutes,4HA77@91061|Bacilli,1ZCHY@1386|Bacillus 91061|Bacilli M COG1388 FOG LysM repeat cwlS - - ko:K19223,ko:K19224 - - - - ko00000,ko01000,ko01002,ko01011 - CBM50 - LysM,NLPC_P60,SH3_3 k141_10391_1 861299.J421_3257 1.36e-79 253.0 COG0504@1|root,COG0504@2|Bacteria,1ZT0J@142182|Gemmatimonadetes 142182|Gemmatimonadetes F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates pyrG - 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 - - - CTP_synth_N,GATase k141_3045_1 1122194.AUHU01000004_gene1446 2.86e-72 231.0 COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,1RPZC@1236|Gammaproteobacteria,465AN@72275|Alteromonadaceae 1236|Gammaproteobacteria J exonuclease of the beta-lactamase fold involved in RNA processing - - - ko:K07576 - - - - ko00000 - - - Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL k141_11613_1 1294265.JCM21738_1289 7.91e-52 165.0 COG2210@1|root,COG2210@2|Bacteria,1V3UE@1239|Firmicutes,4HH93@91061|Bacilli,1ZQ9Q@1386|Bacillus 91061|Bacilli S DsrE/DsrF-like family - - - - - - - - - - - - DrsE_2 k141_11613_2 935836.JAEL01000049_gene5367 2.93e-68 217.0 COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,1TPE2@1239|Firmicutes,4H9WH@91061|Bacilli,1ZCWN@1386|Bacillus 91061|Bacilli P Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B,Rhodanese k141_12829_1 768066.HELO_3330 7.58e-54 179.0 COG0609@1|root,COG0609@2|Bacteria,1R34J@1224|Proteobacteria,1T637@1236|Gammaproteobacteria,1XIH0@135619|Oceanospirillales 135619|Oceanospirillales P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily - - - ko:K02015 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - FecCD k141_12829_2 1238190.AMQY01000001_gene630 1.6e-42 147.0 COG0609@1|root,COG0609@2|Bacteria,1MYYG@1224|Proteobacteria,1RRQ1@1236|Gammaproteobacteria,1XHAA@135619|Oceanospirillales 135619|Oceanospirillales P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily - - - ko:K02015 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - FecCD k141_14960_2 218284.CCDN010000001_gene1535 6.71e-50 160.0 COG3152@1|root,COG3152@2|Bacteria,1VDSW@1239|Firmicutes,4HMMJ@91061|Bacilli,1ZGXZ@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF805) yhaH - - - - - - - - - - - DUF805 k141_32745_1 218284.CCDN010000001_gene1488 6.31e-105 315.0 COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,4H9SZ@91061|Bacilli,1ZAX7@1386|Bacillus 91061|Bacilli E Sodium alanine symporter glnT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03310,ko:K11626 ko02020,map02020 - - - ko00000,ko00001 2.A.25 - - Na_Ala_symp k141_17349_1 1294265.JCM21738_5074 3e-133 385.0 COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,4HA6H@91061|Bacilli,1ZB1B@1386|Bacillus 91061|Bacilli E Cysteine desulfurase iscS - 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - - Aminotran_5 k141_7836_1 1453501.JELR01000002_gene1054 7.6e-128 377.0 COG2010@1|root,COG2010@2|Bacteria 2|Bacteria C Cytochrome c - - - ko:K17230 ko00920,ko01120,map00920,map01120 - R09499 - ko00000,ko00001 - - - Cytochrom_C,Cytochrome_CBB3,OmpA k141_24582_1 1122917.KB899661_gene970 1.02e-67 211.0 COG1876@1|root,COG1876@2|Bacteria,1V69M@1239|Firmicutes,4HI21@91061|Bacilli,26UX9@186822|Paenibacillaceae 91061|Bacilli M PFAM peptidase M15B and M15C DD-carboxypeptidase VanY endolysin - - - ko:K17733 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_M15_4 k141_23508_2 218284.CCDN010000001_gene222 4.83e-147 421.0 COG0616@1|root,COG0616@2|Bacteria,1TRQW@1239|Firmicutes,4HB4R@91061|Bacilli,1ZBTV@1386|Bacillus 91061|Bacilli OU signal peptide peptidase SppA sppA - - ko:K04773 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S49 k141_9196_2 247639.MGP2080_12793 4.11e-07 56.6 COG4773@1|root,COG4773@2|Bacteria,1QTXJ@1224|Proteobacteria,1T2BS@1236|Gammaproteobacteria 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec k141_19818_2 1453501.JELR01000001_gene2744 0.0 981.0 COG0025@1|root,COG0025@2|Bacteria,1QTUE@1224|Proteobacteria,1T1HJ@1236|Gammaproteobacteria,4657N@72275|Alteromonadaceae 1236|Gammaproteobacteria P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family nhaP - - ko:K03316 - - - - ko00000 2.A.36 - - Na_H_Exchanger,TrkA_N k141_19818_3 1298593.TOL_1201 8.19e-93 275.0 COG0590@1|root,COG0590@2|Bacteria,1RE8P@1224|Proteobacteria,1S3V3@1236|Gammaproteobacteria,1XJK0@135619|Oceanospirillales 135619|Oceanospirillales FJ MafB19-like deaminase - - 3.5.4.1 ko:K01485 ko00240,ko00330,ko01100,map00240,map00330,map01100 - R00974,R01411,R02922 RC00074,RC00514,RC00809 ko00000,ko00001,ko01000 - - - dCMP_cyt_deam_1 k141_19818_4 187272.Mlg_1916 1.06e-118 350.0 COG0697@1|root,COG0697@2|Bacteria,1QWRA@1224|Proteobacteria,1T2X5@1236|Gammaproteobacteria,1WZKJ@135613|Chromatiales 135613|Chromatiales EG EamA-like transporter family - - - - - - - - - - - - EamA k141_18770_1 1071073.KI530548_gene3472 2.23e-40 148.0 COG1199@1|root,COG1199@2|Bacteria,1TRNV@1239|Firmicutes,4HBYD@91061|Bacilli,1ZARY@1386|Bacillus 91061|Bacilli KL COG1199 Rad3-related DNA helicases ypvA - 3.6.4.12 ko:K03722 - - - - ko00000,ko01000,ko03400 - - - Helicase_C_2 k141_18770_2 666686.B1NLA3E_20150 2.77e-36 125.0 COG0607@1|root,COG0607@2|Bacteria,1VES3@1239|Firmicutes,4HNRE@91061|Bacilli,1ZI0X@1386|Bacillus 91061|Bacilli P Rhodanese domain protein - - - - - - - - - - - - Rhodanese k141_22172_1 1294265.JCM21738_4460 1.37e-200 560.0 COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,4H9SR@91061|Bacilli,1ZBGE@1386|Bacillus 91061|Bacilli S AI-2E family transporter yrrI GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - - - - - - - - - - AI-2E_transport k141_14971_1 1004785.AMBLS11_04085 1.1e-276 789.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria,46ABP@72275|Alteromonadaceae 1236|Gammaproteobacteria P receptor - - - - - - - - - - - - Plug,STN,TonB_dep_Rec k141_29286_1 1530186.JQEY01000001_gene697 5.2e-12 71.6 COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Resolvase - - - - - - - - - - - - Recombinase,Resolvase,Zn_ribbon_recom k141_27229_1 1246484.D479_13857 5.68e-73 233.0 COG0591@1|root,COG0591@2|Bacteria,1TRYH@1239|Firmicutes,4HE2W@91061|Bacilli,3NECT@45667|Halobacillus 91061|Bacilli E Sodium:solute symporter family - - - - - - - - - - - - SSF k141_22217_1 218284.CCDN010000006_gene3627 3.37e-49 157.0 COG1925@1|root,COG1925@2|Bacteria,1VA0R@1239|Firmicutes,4HKKW@91061|Bacilli,1ZHV0@1386|Bacillus 91061|Bacilli G Phosphocarrier protein Chr crh - - ko:K11184 - - - - ko00000 - - - PTS-HPr k141_16212_2 1453501.JELR01000005_gene1676 0.0 1113.0 COG0188@1|root,COG0188@2|Bacteria,1MURI@1224|Proteobacteria,1RMTC@1236|Gammaproteobacteria,464Q5@72275|Alteromonadaceae 1236|Gammaproteobacteria L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parC GO:0000819,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006276,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007059,GO:0007062,GO:0008150,GO:0008152,GO:0009330,GO:0009987,GO:0016020,GO:0016043,GO:0019897,GO:0019898,GO:0022402,GO:0030541,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0098813,GO:1901360,GO:1901363 - ko:K02621 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseA_C,DNA_topoisoIV k141_35334_1 1294265.JCM21738_489 1.11e-85 257.0 COG1309@1|root,COG1309@2|Bacteria,1V89E@1239|Firmicutes,4HH86@91061|Bacilli,1ZFSK@1386|Bacillus 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - TetR_C_8,TetR_N k141_35334_2 1294265.JCM21738_490 3.08e-13 68.6 COG1033@1|root,COG1033@2|Bacteria,1VSWA@1239|Firmicutes,4HBIV@91061|Bacilli 91061|Bacilli S MMPL family ydfJ - - ko:K07003 - - - - ko00000 - - - MMPL k141_7871_2 1453501.JELR01000002_gene403 2.92e-187 529.0 COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,1RPB4@1236|Gammaproteobacteria,4655S@72275|Alteromonadaceae 1236|Gammaproteobacteria V ABC-2 family transporter protein ybhS - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 k141_7871_3 84531.JMTZ01000138_gene4256 8.58e-23 97.1 COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,1RMM4@1236|Gammaproteobacteria,1X51T@135614|Xanthomonadales 135614|Xanthomonadales V ABC transporter - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_5685_1 218284.CCDN010000001_gene974 5.16e-160 464.0 COG0497@1|root,COG0497@2|Bacteria,1TP99@1239|Firmicutes,4H9ZR@91061|Bacilli,1ZC8B@1386|Bacillus 91061|Bacilli L May be involved in recombinational repair of damaged DNA recN GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - ko:K03631 - - - - ko00000,ko03400 - - - AAA_23,SMC_N k141_18823_1 218284.CCDN010000001_gene988 1.7e-236 692.0 COG1404@1|root,COG4412@1|root,COG1404@2|Bacteria,COG4412@2|Bacteria,1TPUY@1239|Firmicutes,4HBDE@91061|Bacilli,1ZDEQ@1386|Bacillus 91061|Bacilli O COG1404 Subtilisin-like serine proteases bpr GO:0005575,GO:0005576 - ko:K13276 - - - - ko00000,ko01000,ko01002,ko03110 - - - CarbopepD_reg_2,CarboxypepD_reg,Inhibitor_I9,Peptidase_M6,Peptidase_S8 k141_32765_1 218284.CCDN010000005_gene3454 3.12e-53 168.0 2DNAX@1|root,32UIM@2|Bacteria,1VATB@1239|Firmicutes,4HKG4@91061|Bacilli,1ZGXU@1386|Bacillus 91061|Bacilli G Kinase associated protein B kapB GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K06347 ko02020,map02020 - - - ko00000,ko00001 - - - KapB k141_32765_2 218284.CCDN010000005_gene3455 4.75e-45 151.0 COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,4H9V0@91061|Bacilli,1ZBBP@1386|Bacillus 91061|Bacilli O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides ppiA GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 - - - ko00000,ko00001,ko01000,ko03110,ko04147 - - - Pro_isomerase k141_34080_1 218284.CCDN010000001_gene1365 2.93e-73 231.0 COG2223@1|root,COG2223@2|Bacteria,1TPTN@1239|Firmicutes,4HA7C@91061|Bacilli,1ZB21@1386|Bacillus 91061|Bacilli P COG0477 Permeases of the major facilitator superfamily fsr GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K08223 - - - - ko00000,ko02000 2.A.1.35 - - MFS_1 k141_24609_1 218284.CCDN010000007_gene3971 5.47e-173 490.0 COG0766@1|root,COG0766@2|Bacteria,1TPAU@1239|Firmicutes,4H9KI@91061|Bacilli,1ZASB@1386|Bacillus 91061|Bacilli M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine murA GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008760,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042221,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0070589,GO:0070887,GO:0071236,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R00660 RC00350 ko00000,ko00001,ko01000,ko01011 - - iYO844.BSU37100 EPSP_synthase k141_25883_1 1294265.JCM21738_1708 5.38e-130 380.0 COG1113@1|root,COG1113@2|Bacteria,1TP97@1239|Firmicutes,4H9QX@91061|Bacilli,1ZDGG@1386|Bacillus 91061|Bacilli E COG1113 Gamma-aminobutyrate permease and related permeases ycgH GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03293 - - - - ko00000 2.A.3.1 - - AA_permease k141_19856_1 1042377.AFPJ01000043_gene955 5.25e-126 384.0 COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,1RQEX@1236|Gammaproteobacteria,463Z7@72275|Alteromonadaceae 1236|Gammaproteobacteria M Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane lptD GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0009279,GO:0009636,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0042221,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0050896,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:1901264 - ko:K04744 - - - - ko00000,ko02000 1.B.42.1 - iG2583_1286.G2583_0058 OstA,OstA_C k141_14972_1 1279017.AQYJ01000029_gene3360 7.3e-172 492.0 COG2114@1|root,COG2114@2|Bacteria,1MV1V@1224|Proteobacteria,1RYBQ@1236|Gammaproteobacteria,464T6@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) cyaB - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_cyc,MASE2 k141_27232_1 886293.Sinac_2869 2.87e-35 130.0 COG1899@1|root,COG1899@2|Bacteria,2IY4N@203682|Planctomycetes 203682|Planctomycetes O Deoxyhypusine synthase - - 2.5.1.46 ko:K00809 - - - - ko00000,ko01000 - - - DS k141_27232_2 1392502.JNIO01000008_gene1829 5.48e-13 69.7 COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,4H1UX@909932|Negativicutes 909932|Negativicutes S DHHA1 domain protein nrnA - 3.1.13.3,3.1.3.7 ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 - R00188,R00508 RC00078 ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1 k141_7872_1 1294265.JCM21738_1828 5.91e-84 258.0 29S7G@1|root,30DBY@2|Bacteria,1UB4F@1239|Firmicutes,4IMH1@91061|Bacilli,1ZK50@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_16213_2 323850.Shew_2870 3.32e-70 236.0 COG4774@1|root,COG4774@2|Bacteria,1NMCN@1224|Proteobacteria,1T3TQ@1236|Gammaproteobacteria,2QEVB@267890|Shewanellaceae 1236|Gammaproteobacteria P TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_18825_1 1117108.PAALTS15_29326 2.05e-63 201.0 COG4430@1|root,COG4430@2|Bacteria,1V41W@1239|Firmicutes,4HDKN@91061|Bacilli,26UM3@186822|Paenibacillaceae 91061|Bacilli S Bacteriocin-protection, YdeI or OmpD-Associated - - - - - - - - - - - - OmdA k141_19857_1 1121938.AUDY01000012_gene3691 3.04e-65 211.0 COG0446@1|root,COG0446@2|Bacteria,1TPWW@1239|Firmicutes,4H9U7@91061|Bacilli,3NG8R@45667|Halobacillus 91061|Bacilli S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain nox - 1.6.3.4 ko:K17869 - - - - ko00000,ko01000 - - - Pyr_redox_2,Pyr_redox_dim k141_14139_1 1230341.MJ3_10396 3.82e-55 183.0 COG2066@1|root,COG2066@2|Bacteria,1TP64@1239|Firmicutes,4H9XA@91061|Bacilli 91061|Bacilli E Belongs to the glutaminase family glsA - 3.5.1.2 ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 - R00256,R01579 RC00010,RC02798 ko00000,ko00001,ko01000 - - - Glutaminase k141_14139_2 1002809.SSIL_2257 3.93e-22 90.5 COG3265@1|root,COG3265@2|Bacteria,1UNH1@1239|Firmicutes,4IUE2@91061|Bacilli,26ESF@186818|Planococcaceae 91061|Bacilli G AAA domain - - - - - - - - - - - - AAA_18 k141_34081_1 1347086.CCBA010000011_gene1655 9.42e-70 222.0 COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,4HAE3@91061|Bacilli,1ZDU5@1386|Bacillus 91061|Bacilli E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component braC - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 k141_34081_2 1117379.BABA_23243 8.2e-20 87.0 COG0411@1|root,COG0411@2|Bacteria,1TR0P@1239|Firmicutes,4HASG@91061|Bacilli,1ZB0Q@1386|Bacillus 91061|Bacilli E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component - - - ko:K01995 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C k141_24611_1 1279017.AQYJ01000026_gene209 1.98e-104 302.0 COG1522@1|root,COG1522@2|Bacteria,1RDB3@1224|Proteobacteria,1S2E1@1236|Gammaproteobacteria,46CRE@72275|Alteromonadaceae 1236|Gammaproteobacteria K AsnC-type helix-turn-helix domain ybaO - - ko:K05800 - - - - ko00000,ko03000 - - - AsnC_trans_reg,HTH_24 k141_36272_2 1116375.VEJY3_16026 3.43e-131 373.0 COG4341@1|root,COG4341@2|Bacteria,1QHQD@1224|Proteobacteria,1S2ZI@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phosphohydrolase - - - - - - - - - - - - HD k141_36272_4 1116375.VEJY3_22986 3.62e-181 508.0 COG0697@1|root,COG0697@2|Bacteria,1MWSU@1224|Proteobacteria,1RSF8@1236|Gammaproteobacteria,1XTMR@135623|Vibrionales 135623|Vibrionales EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - - - - - - - - - - EamA k141_36272_5 1187848.AJYQ01000079_gene1173 5.7e-153 436.0 COG0697@1|root,COG0697@2|Bacteria,1PHRI@1224|Proteobacteria,1RSFS@1236|Gammaproteobacteria,1XURH@135623|Vibrionales 135623|Vibrionales EG of the drug metabolite transporter (DMT) superfamily - - - - - - - - - - - - EamA k141_3083_1 1178537.BA1_18367 3.17e-85 262.0 COG1783@1|root,COG1783@2|Bacteria,1TRQP@1239|Firmicutes,4HDMY@91061|Bacilli,1ZCXF@1386|Bacillus 91061|Bacilli S phage terminase, large subunit - - - ko:K06909 - - - - ko00000 - - - Terminase_3,Terminase_3C k141_14973_1 1453501.JELR01000005_gene1636 9.99e-150 429.0 COG4948@1|root,COG4948@2|Bacteria,1MURK@1224|Proteobacteria,1RNRB@1236|Gammaproteobacteria,46663@72275|Alteromonadaceae 1236|Gammaproteobacteria M mandelate racemase muconate lactonizing rspA GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0008150,GO:0008152,GO:0008927,GO:0009056,GO:0016052,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043169,GO:0044238,GO:0046872,GO:0047929,GO:0071704,GO:1901575 4.2.1.8 ko:K08323 ko00040,ko01100,map00040,map01100 M00061 R05606 RC00543 ko00000,ko00001,ko00002,ko01000 - - - MR_MLE_C,MR_MLE_N k141_25884_2 1196031.ALEG01000004_gene4654 1.97e-61 202.0 COG4712@1|root,COG4712@2|Bacteria,1VENV@1239|Firmicutes,4HX6K@91061|Bacilli,1ZJDG@1386|Bacillus 91061|Bacilli S Rad52/22 family double-strand break repair protein - - - - - - - - - - - - Rad52_Rad22 k141_4304_1 1453501.JELR01000001_gene3242 0.0 1043.0 COG1262@1|root,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,1RQVS@1236|Gammaproteobacteria,46674@72275|Alteromonadaceae 1236|Gammaproteobacteria S PEGA domain - - - - - - - - - - - - FGE-sulfatase,PEGA k141_14140_1 935836.JAEL01000150_gene1850 1.02e-101 300.0 COG1028@1|root,COG1028@2|Bacteria,1TP3G@1239|Firmicutes,4HACT@91061|Bacilli,1ZDEW@1386|Bacillus 91061|Bacilli IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate - - 1.1.1.30 ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 M00088 R01361 RC00117 ko00000,ko00001,ko00002,ko01000 - - - adh_short_C2 k141_5686_1 42565.FP66_10980 9.85e-31 119.0 COG3115@1|root,COG3115@2|Bacteria,1MVHR@1224|Proteobacteria,1RMDB@1236|Gammaproteobacteria,1XKA8@135619|Oceanospirillales 135619|Oceanospirillales D Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins zipA - - ko:K03528 - - - - ko00000,ko03036 - - - ZipA_C k141_28162_1 1453501.JELR01000005_gene1663 4.05e-105 315.0 COG1252@1|root,COG1252@2|Bacteria,1MX96@1224|Proteobacteria,1RM9I@1236|Gammaproteobacteria,464B3@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1252 NADH dehydrogenase, FAD-containing subunit ndh - 1.6.99.3 ko:K03885 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - Pyr_redox_2 k141_7963_1 1033734.CAET01000075_gene2748 3.39e-33 122.0 COG2755@1|root,COG2755@2|Bacteria,1UH1X@1239|Firmicutes,4HE8E@91061|Bacilli,1ZG9K@1386|Bacillus 91061|Bacilli E GDSL-like Lipase/Acylhydrolase - - - - - - - - - - - - Lipase_GDSL_2,SLH,fn3 k141_24861_2 1453501.JELR01000001_gene2410 5.67e-132 402.0 COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,1RN05@1236|Gammaproteobacteria,464MR@72275|Alteromonadaceae 1236|Gammaproteobacteria S Insulinase (Peptidase family M16) pqqL - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C k141_16474_1 1279017.AQYJ01000027_gene1982 1.76e-206 593.0 COG4206@1|root,COG4206@2|Bacteria,1MUZG@1224|Proteobacteria,1RP7I@1236|Gammaproteobacteria,463Z2@72275|Alteromonadaceae 1236|Gammaproteobacteria H COG1629 Outer membrane receptor proteins, mostly Fe transport - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - CarboxypepD_reg,Plug,TonB_dep_Rec k141_10550_2 218284.CCDN010000001_gene532 2.79e-187 524.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,4H9NS@91061|Bacilli,1ZCF9@1386|Bacillus 91061|Bacilli G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family gapB GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016491,GO:0016620,GO:0016903,GO:0019318,GO:0019319,GO:0036094,GO:0043891,GO:0044238,GO:0044281,GO:0044283,GO:0046364,GO:0048037,GO:0050661,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N k141_17575_2 1453501.JELR01000001_gene3075 4.15e-47 157.0 2CD3D@1|root,32RWZ@2|Bacteria,1N61G@1224|Proteobacteria,1SB8Q@1236|Gammaproteobacteria,46BJ4@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF4440) - - - - - - - - - - - - DUF4440 k141_17575_3 1042377.AFPJ01000034_gene2338 5.56e-239 665.0 COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,1RMZD@1236|Gammaproteobacteria,463YJ@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine hisD - 1.1.1.23 ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01158,R01163,R03012 RC00099,RC00242,RC00463 ko00000,ko00001,ko00002,ko01000 - - - Histidinol_dh k141_2084_1 218284.CCDN010000001_gene197 4.08e-176 496.0 COG0598@1|root,COG0598@2|Bacteria,1TPSV@1239|Firmicutes,4HAPC@91061|Bacilli,1ZBVW@1386|Bacillus 91061|Bacilli P Mediates influx of magnesium ions corA - - ko:K03284 - - - - ko00000,ko02000 1.A.35.1,1.A.35.3 - - CorA k141_20152_1 1279017.AQYJ01000024_gene969 3.56e-236 672.0 COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,1RP14@1236|Gammaproteobacteria,464DK@72275|Alteromonadaceae 1236|Gammaproteobacteria J Belongs to the class-I aminoacyl-tRNA synthetase family leuS GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - iECOK1_1307.ECOK1_0652,iECS88_1305.ECS88_0684,iNRG857_1313.NRG857_02925,iPC815.YPO2610 Anticodon_1,tRNA-synt_1,tRNA-synt_1_2 k141_20152_3 1279017.AQYJ01000024_gene968 3.79e-79 239.0 COG2980@1|root,COG2980@2|Bacteria,1NGPX@1224|Proteobacteria,1SGKQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane lptE - - ko:K03643 - - - - ko00000,ko02000 1.B.42.1 - - LptE k141_34320_1 218284.CCDN010000001_gene1103 1.58e-29 105.0 2EJSH@1|root,33DH6@2|Bacteria,1VMUI@1239|Firmicutes,4HS5M@91061|Bacilli,1ZJ2B@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2768) yphE - - - - - - - - - - - DUF2768 k141_29571_1 1121939.L861_11665 1.08e-77 249.0 COG0366@1|root,COG0366@2|Bacteria,1MVKX@1224|Proteobacteria,1RMXP@1236|Gammaproteobacteria,1XHYU@135619|Oceanospirillales 135619|Oceanospirillales G Alpha amylase, catalytic domain - - 2.4.1.7 ko:K00690 ko00500,map00500 - R00803 RC00028 ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,Malt_amylase_C k141_5924_1 1116375.VEJY3_07485 1.07e-28 117.0 28M2E@1|root,2ZAGW@2|Bacteria,1R97D@1224|Proteobacteria,1RURR@1236|Gammaproteobacteria,1XVXB@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_17576_1 279010.BL03334 2.53e-25 101.0 2BKBV@1|root,32ESB@2|Bacteria,1V8VF@1239|Firmicutes,4HK9W@91061|Bacilli,1ZSJN@1386|Bacillus 91061|Bacilli S Tripartite tricarboxylate transporter TctB family - - - ko:K07794 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.80.1 - - TctB k141_17576_2 279010.BL03332 2.64e-24 100.0 COG3181@1|root,COG3181@2|Bacteria,1V0HH@1239|Firmicutes,4HBWA@91061|Bacilli,1ZB42@1386|Bacillus 91061|Bacilli S Tripartite tricarboxylate transporter family receptor - - - ko:K07795 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.80.1 - - TctC k141_24863_1 1294265.JCM21738_1434 1.12e-106 313.0 COG2367@1|root,COG2367@2|Bacteria,1UYZ3@1239|Firmicutes,4HD7T@91061|Bacilli,1ZGIF@1386|Bacillus 91061|Bacilli V Beta-lactamase enzyme family - - 3.5.2.6 ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 M00627,M00628 R06363 RC01499 ko00000,ko00001,ko00002,ko01000,ko01504 - - - Beta-lactamase2 k141_28163_1 460265.Mnod_7299 3.8e-06 48.1 COG1028@1|root,COG1028@2|Bacteria,1MWJI@1224|Proteobacteria,2TRNJ@28211|Alphaproteobacteria,1JTKS@119045|Methylobacteriaceae 28211|Alphaproteobacteria IQ PFAM short-chain dehydrogenase reductase SDR - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 k141_28163_2 316274.Haur_0750 3.89e-16 75.9 COG1302@1|root,COG1302@2|Bacteria,2G7GB@200795|Chloroflexi 200795|Chloroflexi S Asp23 family, cell envelope-related function - - - - - - - - - - - - Asp23 k141_28163_3 926569.ANT_14610 1.37e-18 81.6 COG0781@1|root,COG0781@2|Bacteria,2G6XA@200795|Chloroflexi 200795|Chloroflexi K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons nusB - - ko:K03625 - - - - ko00000,ko03009,ko03021 - - - NusB k141_3320_1 218284.CCDN010000002_gene2062 1.34e-180 511.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HBTP@91061|Bacilli,1ZATT@1386|Bacillus 91061|Bacilli I acyl-CoA dehydrogenase - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_2,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_21097_1 1116375.VEJY3_07970 2.3e-142 409.0 COG0842@1|root,COG0842@2|Bacteria,1R4QG@1224|Proteobacteria,1RTXK@1236|Gammaproteobacteria,1XTRK@135623|Vibrionales 135623|Vibrionales V ABC-type multidrug transport system, permease component - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 k141_21097_2 672.VV93_v1c44240 1.09e-108 325.0 COG0697@1|root,COG0697@2|Bacteria,1MUQ7@1224|Proteobacteria,1RN1M@1236|Gammaproteobacteria,1XVHB@135623|Vibrionales 135623|Vibrionales EG of the drug metabolite transporter (DMT) superfamily - - - ko:K03298 - - - - ko00000,ko02000 2.A.7.3 - - EamA k141_21097_3 223926.28806710 2.57e-221 612.0 COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,1RPPQ@1236|Gammaproteobacteria,1XWFX@135623|Vibrionales 135623|Vibrionales C cytochrome c peroxidase - - 1.11.1.5 ko:K00428 - - - - ko00000,ko01000 - - - CCP_MauG,Cytochrom_C k141_21097_4 1116375.VEJY3_07975 0.0 902.0 COG0527@1|root,COG0527@2|Bacteria,1MVSI@1224|Proteobacteria,1RQ37@1236|Gammaproteobacteria,1XUVY@135623|Vibrionales 135623|Vibrionales E Amino acid kinase family - - 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase k141_21097_5 1116375.VEJY3_07980 9.06e-92 268.0 COG0662@1|root,COG0662@2|Bacteria,1QU6E@1224|Proteobacteria,1T256@1236|Gammaproteobacteria,1XWZZ@135623|Vibrionales 135623|Vibrionales G Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant ectC - 4.2.1.108 ko:K06720 ko00260,ko01100,ko01120,map00260,map01100,map01120 M00033 R06979 RC01729 ko00000,ko00001,ko00002,ko01000 - - - Ectoine_synth k141_21097_6 1116375.VEJY3_07985 1.2e-301 823.0 COG0160@1|root,COG0160@2|Bacteria,1MWY6@1224|Proteobacteria,1RQKU@1236|Gammaproteobacteria,1XT3C@135623|Vibrionales 135623|Vibrionales E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family ectB GO:0003674,GO:0003824,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0018130,GO:0019491,GO:0019752,GO:0032787,GO:0042399,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.6.1.76 ko:K00836 ko00260,ko01100,ko01120,ko01210,ko01230,map00260,map01100,map01120,map01210,map01230 M00033 R06977 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 k141_21097_7 1116375.VEJY3_07990 2.81e-121 346.0 COG0454@1|root,COG0456@2|Bacteria,1RHB7@1224|Proteobacteria,1S3TD@1236|Gammaproteobacteria,1XVUK@135623|Vibrionales 135623|Vibrionales K L-2,4-diaminobutyric acid acetyltransferase ectA GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016407,GO:0016740,GO:0016746,GO:0016747,GO:0018130,GO:0019491,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0042399,GO:0043170,GO:0043412,GO:0043436,GO:0043543,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.3.1.178 ko:K06718 ko00260,ko01100,ko01120,map00260,map01100,map01120 M00033 R06978 RC00004,RC00096 ko00000,ko00001,ko00002,ko01000 - - - Acetyltransf_1 k141_21097_8 1116375.VEJY3_07995 1.41e-264 727.0 COG4175@1|root,COG4175@2|Bacteria,1MU86@1224|Proteobacteria,1RN2R@1236|Gammaproteobacteria,1XTVT@135623|Vibrionales 135623|Vibrionales E COG4175 ABC-type proline glycine betaine transport system, ATPase component proV - 3.6.3.32 ko:K02000 ko02010,map02010 M00208 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.12 - - ABC_tran,CBS k141_21097_9 1116375.VEJY3_08000 3.85e-16 76.6 COG4176@1|root,COG4176@2|Bacteria,1MUM4@1224|Proteobacteria,1RPQS@1236|Gammaproteobacteria,1XTMM@135623|Vibrionales 135623|Vibrionales P COG4176 ABC-type proline glycine betaine transport system, permease component proW - - ko:K02001 ko02010,map02010 M00208 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - BPD_transp_1 k141_24864_1 1294265.JCM21738_1655 9.53e-78 239.0 COG0457@1|root,COG0457@2|Bacteria,1UBH2@1239|Firmicutes,4HB47@91061|Bacilli,1ZD40@1386|Bacillus 91061|Bacilli S COG0457 FOG TPR repeat yvcD - - - - - - - - - - - HTH_psq,TPR_16,TPR_19,TPR_2,TPR_8 k141_5925_1 1279017.AQYJ01000027_gene1651 7.72e-55 175.0 COG3245@1|root,COG3245@2|Bacteria,1MZBZ@1224|Proteobacteria,1S9Z9@1236|Gammaproteobacteria,467R4@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG3245 Cytochrome c5 cyc - 1.9.3.1 ko:K02277 ko00190,ko01100,map00190,map01100 M00155 - - ko00000,ko00001,ko00002,ko01000 3.D.4.4 - - Cytochrome_CBB3 k141_17577_1 218284.CCDN010000001_gene1041 6.2e-152 436.0 COG0213@1|root,COG0213@2|Bacteria,1TPCH@1239|Firmicutes,4H9NP@91061|Bacilli,1ZBI1@1386|Bacillus 91061|Bacilli F phosphorylase pdp GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464 2.4.2.2 ko:K00756 ko00240,ko01100,map00240,map01100 - R01570,R01876,R02296,R02484 RC00063 ko00000,ko00001,ko01000 - - - Glycos_trans_3N,Glycos_transf_3,PYNP_C k141_7964_1 1379270.AUXF01000006_gene73 5.7e-56 182.0 COG0669@1|root,COG0669@2|Bacteria,1ZTTQ@142182|Gemmatimonadetes 142182|Gemmatimonadetes H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate coaD - 2.7.7.3 ko:K00954 ko00770,ko01100,map00770,map01100 M00120 R03035 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like k141_7964_2 627192.SLG_37020 3.21e-39 145.0 COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,2TRPK@28211|Alphaproteobacteria,2K0HJ@204457|Sphingomonadales 204457|Sphingomonadales E Catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate aspB - 2.6.1.1 ko:K00812 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 - R00355,R00694,R00734,R00896,R02433,R02619,R05052 RC00006 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 k141_16476_1 218284.CCDN010000002_gene2858 4.54e-98 303.0 COG1657@1|root,COG1657@2|Bacteria,1TRRG@1239|Firmicutes,4HA2Q@91061|Bacilli,1ZBBW@1386|Bacillus 91061|Bacilli I COG1657 Squalene cyclase sqhC - 4.2.1.137 ko:K18115 - - - - ko00000,ko01000 - - - SQHop_cyclase_C,SQHop_cyclase_N k141_20153_1 218284.CCDN010000001_gene694 1.38e-199 557.0 COG1559@1|root,COG1559@2|Bacteria,1TS48@1239|Firmicutes,4HAUV@91061|Bacilli,1ZC44@1386|Bacillus 91061|Bacilli S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation mltG - - ko:K07082 - - - - ko00000 - - - YceG k141_24865_1 644107.SL1157_1591 2.85e-41 140.0 COG0098@1|root,COG0098@2|Bacteria,1MUS4@1224|Proteobacteria,2TSRI@28211|Alphaproteobacteria,4NBG2@97050|Ruegeria 28211|Alphaproteobacteria J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body rpsE GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02988 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S5,Ribosomal_S5_C k141_24865_2 986075.CathTA2_2517 2.88e-08 52.0 COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,4HIGF@91061|Bacilli 91061|Bacilli J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance rplR GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - ko:K02881 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L18p k141_28164_1 218284.CCDN010000001_gene30 5.88e-26 100.0 COG1349@1|root,COG1349@2|Bacteria,1V3MJ@1239|Firmicutes,4HHFC@91061|Bacilli,1ZAV1@1386|Bacillus 91061|Bacilli K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism fapR - - - - - - - - - - - 4HBT,HTH_DeoR,MaoC_dehydratas k141_21098_1 1294265.JCM21738_4202 1.31e-82 254.0 2DH6Y@1|root,2ZYKQ@2|Bacteria,1V3RR@1239|Firmicutes,4HHKE@91061|Bacilli,1ZBHI@1386|Bacillus 91061|Bacilli S Spore germination B3/ GerAC like, C-terminal - - - ko:K06308 - - - - ko00000 - - - Spore_GerAC k141_1179_1 218284.CCDN010000005_gene3402 2.52e-164 468.0 COG2206@1|root,COG2206@2|Bacteria,1TQIM@1239|Firmicutes,4HBV6@91061|Bacilli,1ZCMY@1386|Bacillus 91061|Bacilli T HD domain cnpD3 - - - - - - - - - - - HD,HD_5 k141_3321_1 1266998.ATUJ01000002_gene1885 2.55e-75 239.0 COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,2TUKZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Belongs to the amidase family MA20_19360 - 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Amidase k141_37727_2 1279015.KB908468_gene416 1.3e-215 600.0 COG1902@1|root,COG1902@2|Bacteria,1MVIX@1224|Proteobacteria,1RMFI@1236|Gammaproteobacteria,1Y4Z7@135624|Aeromonadales 135624|Aeromonadales C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family - - - - - - - - - - - - Oxidored_FMN k141_2085_1 218284.CCDN010000001_gene1357 1.61e-12 67.0 COG0514@1|root,COG0514@2|Bacteria,1TPN5@1239|Firmicutes,4H9QP@91061|Bacilli,1ZC4U@1386|Bacillus 91061|Bacilli L DNA helicase recQ GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009378,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.6.4.12 ko:K03654 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind k141_15166_1 1116375.VEJY3_11320 1.04e-110 336.0 COG0665@1|root,COG4121@1|root,COG0665@2|Bacteria,COG4121@2|Bacteria,1MZW5@1224|Proteobacteria,1RMTE@1236|Gammaproteobacteria,1XSRW@135623|Vibrionales 135623|Vibrionales J Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 mnmC GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0004808,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016491,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0055114,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.61 ko:K15461 - - R00601,R08702 RC00003,RC00053,RC00060,RC01483 ko00000,ko01000,ko03016 - - - DAO,Methyltransf_30 k141_15166_2 1116375.VEJY3_11315 1.92e-282 773.0 COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria,1XT7W@135623|Vibrionales 135623|Vibrionales IQ Belongs to the beta-ketoacyl-ACP synthases family fabB - 2.3.1.41 ko:K00647 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt k141_15166_3 1116375.VEJY3_11295 3.18e-261 717.0 COG0111@1|root,COG0111@2|Bacteria,1N5TD@1224|Proteobacteria,1RMFW@1236|Gammaproteobacteria,1XSPZ@135623|Vibrionales 135623|Vibrionales H Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate pdxB GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.1.1.290 ko:K03473 ko00750,ko01100,map00750,map01100 M00124 R04210 RC00084 ko00000,ko00001,ko00002,ko01000 - - - 2-Hacid_dh,2-Hacid_dh_C,DUF3410 k141_15166_4 1116375.VEJY3_11290 6.76e-245 672.0 COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,1RNB6@1236|Gammaproteobacteria,1XT9P@135623|Vibrionales 135623|Vibrionales E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate asd GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004073,GO:0006082,GO:0006520,GO:0006549,GO:0006553,GO:0006555,GO:0006566,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009081,GO:0009082,GO:0009085,GO:0009086,GO:0009088,GO:0009089,GO:0009097,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC k141_15166_5 1116375.VEJY3_11285 1.1e-69 234.0 COG3170@1|root,COG3170@2|Bacteria,1MXV7@1224|Proteobacteria,1RMM5@1236|Gammaproteobacteria,1XUV6@135623|Vibrionales 135623|Vibrionales NU COG3170 Tfp pilus assembly protein FimV - - - ko:K08086 - - - - ko00000 - - - - k141_13039_1 1042377.AFPJ01000028_gene2229 7.8e-148 429.0 COG4324@1|root,COG4324@2|Bacteria,1N0FE@1224|Proteobacteria,1S0UK@1236|Gammaproteobacteria,46ACH@72275|Alteromonadaceae 1236|Gammaproteobacteria S Putative aminopeptidase - - - - - - - - - - - - Aminopep k141_13039_3 1279017.AQYJ01000028_gene2021 2.77e-163 466.0 COG0451@1|root,COG0451@2|Bacteria,1RKZT@1224|Proteobacteria,1S4B4@1236|Gammaproteobacteria,468WR@72275|Alteromonadaceae 1236|Gammaproteobacteria M NmrA-like family - - 1.1.1.219 ko:K00091 - - - - ko00000,ko01000 - - - Abhydrolase_6,Epimerase,NAD_binding_4 k141_13039_5 1279017.AQYJ01000028_gene2022 2.31e-107 313.0 COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,1S25K@1236|Gammaproteobacteria,466DD@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG2818 3-methyladenine DNA glycosylase tag - 3.2.2.20 ko:K01246 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Adenine_glyco k141_13039_6 1453501.JELR01000002_gene1275 5.31e-121 354.0 COG0668@1|root,COG0668@2|Bacteria,1N596@1224|Proteobacteria,1RQZP@1236|Gammaproteobacteria,464UB@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0668 Small-conductance mechanosensitive channel - - - ko:K03442 - - - - ko00000,ko02000 1.A.23.2 - - MS_channel,TM_helix k141_13039_7 1565129.JSFF01000023_gene2807 5.08e-53 172.0 COG1285@1|root,COG1285@2|Bacteria,1MURJ@1224|Proteobacteria,1RQUD@1236|Gammaproteobacteria,2QD40@267890|Shewanellaceae 1236|Gammaproteobacteria S MgtC family mgtC GO:0008150,GO:0009405,GO:0044419,GO:0051704 - ko:K07507 - - - - ko00000,ko02000 9.B.20 - - MgtC k141_7965_1 218284.CCDN010000006_gene3746 1.43e-126 390.0 COG3459@1|root,COG3459@2|Bacteria,1TVMK@1239|Firmicutes,4H9ZP@91061|Bacilli,1ZF4F@1386|Bacillus 91061|Bacilli G Glycosyl hydrolase 36 superfamily, catalytic domain chvB1 - 2.4.1.20,2.4.1.333 ko:K00702,ko:K13688,ko:K21298 ko00500,ko01100,map00500,map01100 - R00952 RC00049 ko00000,ko00001,ko01000,ko01003 - GH94,GT36,GT84 - Glyco_hydro_36,Glyco_transf_36 k141_5926_2 1042377.AFPJ01000008_gene1958 1.11e-128 374.0 COG2850@1|root,COG2850@2|Bacteria,1MUAC@1224|Proteobacteria,1RQQP@1236|Gammaproteobacteria,465RI@72275|Alteromonadaceae 1236|Gammaproteobacteria S Cupin-like domain - - - - - - - - - - - - Cupin_8 k141_30471_4 243924.LT42_09770 1.17e-72 220.0 COG1764@1|root,COG1764@2|Bacteria,1RD1A@1224|Proteobacteria,1S4IY@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Organic Hydroperoxide Resistance Protein ohr - - - - - - - - - - - OsmC k141_30471_5 745411.B3C1_14455 1.96e-52 170.0 COG1846@1|root,COG1846@2|Bacteria,1RH1F@1224|Proteobacteria,1S8WM@1236|Gammaproteobacteria,1J6V0@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria K COG1846 Transcriptional regulators ohrR - - - - - - - - - - - MarR k141_17579_1 247633.GP2143_13661 4.22e-56 182.0 COG0428@1|root,COG0428@2|Bacteria,1R40E@1224|Proteobacteria,1RRYS@1236|Gammaproteobacteria,1J6RV@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P ZIP Zinc transporter - - - ko:K16267 - - - - ko00000,ko02000 2.A.5.4.11 - - Zip k141_35636_2 1453501.JELR01000001_gene3213 5.03e-16 73.6 2CHJ0@1|root,33FNQ@2|Bacteria,1NNVV@1224|Proteobacteria,1SGKA@1236|Gammaproteobacteria,46C5Z@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - DUF883 k141_4543_1 1499680.CCFE01000021_gene2279 4.39e-68 212.0 COG2761@1|root,COG2761@2|Bacteria,1TZ1N@1239|Firmicutes,4HEBF@91061|Bacilli,1ZD4M@1386|Bacillus 91061|Bacilli Q dithiol-disulfide isomerase involved in polyketide biosynthesis frnE - 5.3.4.1 ko:K01829 - - - - ko00000,ko01000 - - - DSBA k141_35656_1 1279017.AQYJ01000027_gene1717 9.37e-52 173.0 COG1721@1|root,COG1721@2|Bacteria,1MWPG@1224|Proteobacteria,1S4TD@1236|Gammaproteobacteria,46B1X@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function DUF58 - - - - - - - - - - - - DUF58 k141_35656_2 983548.Krodi_2001 8.87e-09 62.0 COG1572@1|root,COG1572@2|Bacteria,4PMQV@976|Bacteroidetes,1IJWS@117743|Flavobacteriia 976|Bacteroidetes S Aerotolerance regulator N-terminal - - - - - - - - - - - - BatA k141_30483_1 218284.CCDN010000001_gene1161 1.09e-55 174.0 COG3599@1|root,COG3599@2|Bacteria,1VEQ4@1239|Firmicutes,4HNP1@91061|Bacilli,1ZQAY@1386|Bacillus 91061|Bacilli D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation gpsB - - - - - - - - - - - DivIVA k141_13058_1 768710.DesyoDRAFT_0195 3.97e-47 162.0 COG1606@1|root,COG1606@2|Bacteria,1TPB2@1239|Firmicutes,2485J@186801|Clostridia,260CU@186807|Peptococcaceae 186801|Clostridia S TIGRFAM TIGR00268 family protein - - - ko:K06864 - - - - ko00000 - - - ATP_bind_3,Asn_synthase,NAD_synthase k141_34328_1 1279017.AQYJ01000029_gene3599 2.12e-240 665.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RMMJ@1236|Gammaproteobacteria,4640M@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1960 Acyl-CoA dehydrogenases - - - ko:K04117 ko00362,ko01120,map00362,map01120 M00540 R05619 RC02035 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_34328_2 1042377.AFPJ01000009_gene273 6.52e-146 420.0 COG0697@1|root,COG0697@2|Bacteria,1QSKQ@1224|Proteobacteria,1RYG1@1236|Gammaproteobacteria,466BE@72275|Alteromonadaceae 1236|Gammaproteobacteria EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - ko:K07052 - - - - ko00000 - - - EamA k141_34328_4 1279017.AQYJ01000029_gene3597 0.0 1819.0 COG0506@1|root,COG4230@1|root,COG0506@2|Bacteria,COG4230@2|Bacteria,1MV93@1224|Proteobacteria,1RN48@1236|Gammaproteobacteria,463XX@72275|Alteromonadaceae 1236|Gammaproteobacteria CE Oxidizes proline to glutamate for use as a carbon and nitrogen source putA - 1.2.1.88,1.5.5.2 ko:K13821 ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130 - R00245,R00707,R00708,R01253,R04444,R04445,R05051 RC00080,RC00083,RC00216,RC00242,RC00255 ko00000,ko00001,ko01000,ko03000 - - - Aldedh,Pro_dh,Pro_dh-DNA_bdg k141_34328_6 1384054.N790_09875 1.59e-13 73.9 2E5SG@1|root,330GY@2|Bacteria,1NB2M@1224|Proteobacteria,1SCUK@1236|Gammaproteobacteria,1X791@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - k141_20169_1 1279017.AQYJ01000028_gene2318 2.81e-90 270.0 COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,1RMX5@1236|Gammaproteobacteria,4659I@72275|Alteromonadaceae 1236|Gammaproteobacteria K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form cobB GO:0002252,GO:0002376,GO:0003674,GO:0003824,GO:0006464,GO:0006476,GO:0006807,GO:0006935,GO:0006950,GO:0006952,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018205,GO:0019213,GO:0019538,GO:0033558,GO:0034979,GO:0034983,GO:0035601,GO:0036048,GO:0036049,GO:0036055,GO:0036211,GO:0040011,GO:0042221,GO:0042330,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050896,GO:0051607,GO:0051704,GO:0051707,GO:0071704,GO:0098542,GO:0098732,GO:0140096,GO:1901564 - ko:K12410 - - - - ko00000,ko01000 - - - SIR2 k141_24899_1 218284.CCDN010000001_gene988 4.19e-26 107.0 COG1404@1|root,COG4412@1|root,COG1404@2|Bacteria,COG4412@2|Bacteria,1TPUY@1239|Firmicutes,4HBDE@91061|Bacilli,1ZDEQ@1386|Bacillus 91061|Bacilli O COG1404 Subtilisin-like serine proteases bpr GO:0005575,GO:0005576 - ko:K13276 - - - - ko00000,ko01000,ko01002,ko03110 - - - CarbopepD_reg_2,CarboxypepD_reg,Inhibitor_I9,Peptidase_M6,Peptidase_S8 k141_16489_1 1307436.PBF_24825 4.6e-43 142.0 COG2963@1|root,COG2963@2|Bacteria,1VP6M@1239|Firmicutes,4HRHX@91061|Bacilli,1ZIZ1@1386|Bacillus 91061|Bacilli L COG2963 Transposase and inactivated derivatives - - - ko:K07483 - - - - ko00000 - - - HTH_Tnp_1 k141_16489_2 1307436.PBF_24820 2.53e-154 439.0 COG2801@1|root,COG2801@2|Bacteria,1TU21@1239|Firmicutes,4HDK4@91061|Bacilli,1ZB1J@1386|Bacillus 91061|Bacilli L COG2801 Transposase and inactivated derivatives - - - ko:K07497 - - - - ko00000 - - - HTH_21,rve k141_29599_1 674977.VMC_22290 3.04e-200 563.0 28IWB@1|root,2Z8UK@2|Bacteria,1P3IX@1224|Proteobacteria,1RRBU@1236|Gammaproteobacteria,1XSD8@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF3360) - - - - - - - - - - - - DUF3360 k141_29599_2 1238450.VIBNISOn1_p0045 1.12e-52 169.0 COG1670@1|root,COG1670@2|Bacteria,1RIR5@1224|Proteobacteria,1T0YU@1236|Gammaproteobacteria,1XXJK@135623|Vibrionales 135623|Vibrionales J Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_3 k141_21122_1 218284.CCDN010000001_gene1807 2.43e-131 392.0 COG0323@1|root,COG0323@2|Bacteria,1TPGK@1239|Firmicutes,4HB34@91061|Bacilli,1ZB9X@1386|Bacillus 91061|Bacilli L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex mutL GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032300,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1990391 - ko:K03572 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - DNA_mis_repair,HATPase_c_3,MutL_C k141_35657_2 545693.BMQ_4496 1.84e-08 53.1 COG1393@1|root,COG1393@2|Bacteria,1V3QC@1239|Firmicutes,4HH0I@91061|Bacilli,1ZQAW@1386|Bacillus 91061|Bacilli P ArsC family - - - ko:K16509 - - - - ko00000 - - - ArsC k141_33063_2 218284.CCDN010000001_gene1129 2.41e-137 391.0 COG2738@1|root,COG2738@2|Bacteria,1TPD3@1239|Firmicutes,4HB8Z@91061|Bacilli,1ZD1M@1386|Bacillus 91061|Bacilli S Zn-dependent protease yugP - - ko:K06973 - - - - ko00000 - - - Zn_peptidase_2 k141_33063_3 218284.CCDN010000001_gene1130 1.78e-184 515.0 COG1284@1|root,COG1284@2|Bacteria,1TRAU@1239|Firmicutes,4H9UY@91061|Bacilli,1ZBUC@1386|Bacillus 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2179) ypjC - - - - - - - - - - - DUF2179,YitT_membrane k141_7970_1 1116375.VEJY3_05865 8.7e-141 399.0 COG1187@1|root,COG1187@2|Bacteria,1MU6M@1224|Proteobacteria,1RQA9@1236|Gammaproteobacteria,1XTEX@135623|Vibrionales 135623|Vibrionales J Belongs to the pseudouridine synthase RsuA family rsuA GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19 ko:K06183 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 k141_7970_2 1116375.VEJY3_05860 0.0 1159.0 COG1061@1|root,COG1061@2|Bacteria,1MV9F@1224|Proteobacteria,1RNAN@1236|Gammaproteobacteria,1XV70@135623|Vibrionales 135623|Vibrionales KL COG1061 DNA or RNA helicases of superfamily II yejH - - ko:K19789 - - - - ko00000,ko03400 - - - Helicase_C,ResIII k141_7970_3 1116375.VEJY3_05855 1.18e-71 218.0 COG3212@1|root,COG3212@2|Bacteria,1NHDB@1224|Proteobacteria,1SEIC@1236|Gammaproteobacteria,1XXEA@135623|Vibrionales 135623|Vibrionales S peptidase - - - - - - - - - - - - PepSY k141_7970_4 1219076.N646_0251 8.32e-146 412.0 COG0745@1|root,COG0745@2|Bacteria,1N0YI@1224|Proteobacteria,1RMWT@1236|Gammaproteobacteria,1XT4G@135623|Vibrionales 135623|Vibrionales K COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - ko:K02483 - - - - ko00000,ko02022 - - - Response_reg,Trans_reg_C k141_7970_5 1116375.VEJY3_05845 4.41e-268 740.0 COG0642@1|root,COG0642@2|Bacteria,1MX6R@1224|Proteobacteria,1RSAC@1236|Gammaproteobacteria,1XUAK@135623|Vibrionales 135623|Vibrionales T Signal transduction histidine kinase phoQ - - - - - - - - - - - HATPase_c k141_23806_1 218284.CCDN010000001_gene639 3.45e-57 185.0 COG0077@1|root,COG0077@2|Bacteria,1TPDN@1239|Firmicutes,4HA96@91061|Bacilli,1ZAVW@1386|Bacillus 91061|Bacilli E Prephenate dehydratase pheA GO:0003674,GO:0003824,GO:0004664,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0019438,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 4.2.1.51 ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024 R00691,R01373 RC00360 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU27900 ACT,PDT k141_13117_1 315730.BcerKBAB4_1150 2.54e-08 55.1 COG0159@1|root,COG0159@2|Bacteria,1TPXA@1239|Firmicutes,4HFQ8@91061|Bacilli,1ZC5U@1386|Bacillus 91061|Bacilli E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate trpA - 4.2.1.20 ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - Trp_syntA k141_13117_4 1121324.CLIT_2c01920 6.93e-28 112.0 COG0446@1|root,COG0607@1|root,COG2210@1|root,COG0446@2|Bacteria,COG0607@2|Bacteria,COG2210@2|Bacteria,1TPWW@1239|Firmicutes,2484C@186801|Clostridia,25QTC@186804|Peptostreptococcaceae 186801|Clostridia P Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain cdr - - - - - - - - - - - DrsE_2,Pyr_redox_2,Pyr_redox_dim,Rhodanese,TusA k141_34_2 218284.CCDN010000001_gene1123 3.3e-79 238.0 2CSPZ@1|root,32SRK@2|Bacteria,1VBS0@1239|Firmicutes,4HKXQ@91061|Bacilli,1ZI4R@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2487) ypiF - - - - - - - - - - - DUF2487 k141_26192_1 1196031.ALEG01000003_gene3084 3.84e-82 270.0 COG0841@1|root,COG0841@2|Bacteria,1TS55@1239|Firmicutes,4HEH8@91061|Bacilli,1ZEIJ@1386|Bacillus 91061|Bacilli V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran k141_11910_1 218284.CCDN010000005_gene3277 1.91e-110 321.0 28IPR@1|root,2Z8PJ@2|Bacteria,1TPYR@1239|Firmicutes,4HBI7@91061|Bacilli,1ZAX0@1386|Bacillus 91061|Bacilli S Belongs to the UPF0736 family yjbA - - - - - - - - - - - DUF3603 k141_16669_1 218284.CCDN010000005_gene3290 9.67e-47 163.0 COG4469@1|root,COG4469@2|Bacteria,1TRGD@1239|Firmicutes,4HFP5@91061|Bacilli,1ZCFD@1386|Bacillus 91061|Bacilli S Competence protein coiA - - ko:K06198 - - - - ko00000 - - - CoiA k141_28575_1 218284.CCDN010000002_gene2805 8.57e-143 415.0 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli,1ZAXK@1386|Bacillus 91061|Bacilli C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively gabD - 1.2.1.16,1.2.1.20,1.2.1.79 ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 M00027 R00713,R00714,R02401 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_10719_1 565045.NOR51B_2183 3.86e-43 150.0 COG0760@1|root,COG0760@2|Bacteria,1R4ZR@1224|Proteobacteria 1224|Proteobacteria O COG0760 Parvulin-like peptidyl-prolyl isomerase - - - - - - - - - - - - Rotamase_2 k141_14297_2 1116375.VEJY3_12545 1.89e-81 256.0 COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,1RPNE@1236|Gammaproteobacteria,1XTZV@135623|Vibrionales 135623|Vibrionales I COG1022 Long-chain acyl-CoA synthetases (AMP-forming) - - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding k141_3605_2 1453501.JELR01000002_gene1332 8.73e-80 248.0 COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,1RNMZ@1236|Gammaproteobacteria,4658H@72275|Alteromonadaceae 1236|Gammaproteobacteria H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein - - 2.7.1.180 ko:K03734 - - - - ko00000,ko01000 - - - ApbE k141_33319_1 218284.CCDN010000002_gene2714 3.5e-104 317.0 COG1132@1|root,COG1132@2|Bacteria,1VS01@1239|Firmicutes,4HTGJ@91061|Bacilli,1ZEQ6@1386|Bacillus 91061|Bacilli V ABC transporter transmembrane region - - - - - - - - - - - - ABC_membrane,ABC_tran k141_20233_1 384765.SIAM614_02596 9.36e-59 197.0 COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,2TT5E@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q COG3653 N-acyl-D-aspartate D-glutamate deacylase - - - - - - - - - - - - Amidohydro_3 k141_35699_1 218284.CCDN010000006_gene3509 6.47e-53 168.0 COG1393@1|root,COG1393@2|Bacteria,1VA5Q@1239|Firmicutes,4HKQQ@91061|Bacilli,1ZH0I@1386|Bacillus 91061|Bacilli P Belongs to the ArsC family yusI - 1.20.4.1 ko:K00537 - - - - ko00000,ko01000 - - - ArsC,Glutaredoxin k141_19047_1 1116375.VEJY3_15170 0.0 1050.0 COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,1XT2R@135623|Vibrionales 135623|Vibrionales M Gamma-glutamyltranspeptidase ggt - 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept k141_19047_2 223926.28808039 5.02e-161 470.0 COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,1RNJI@1236|Gammaproteobacteria,1XUIR@135623|Vibrionales 135623|Vibrionales L COG0210 Superfamily I DNA and RNA helicases uvrD - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C k141_32116_1 1117647.M5M_07570 9.84e-39 144.0 COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,1RPAB@1236|Gammaproteobacteria,1J56B@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Cysteine-rich domain glcF - - ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001 - - - CCG,Fer4_7,Fer4_8 k141_32116_2 351348.Maqu_3303 6.1e-70 229.0 COG0277@1|root,COG0277@2|Bacteria,1MVYV@1224|Proteobacteria,1RN4G@1236|Gammaproteobacteria,466XK@72275|Alteromonadaceae 1236|Gammaproteobacteria C Glycolate oxidase FAD binding subunit glcE - - ko:K11472 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001 - - - FAD-oxidase_C,FAD_binding_4 k141_32116_3 1042377.AFPJ01000036_gene1148 4.24e-235 660.0 COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,1RQX2@1236|Gammaproteobacteria,463YN@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG0277 FAD FMN-containing dehydrogenases glcD GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0033554,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616 1.1.3.15 ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001,ko01000 - - iJN746.PP_3745,iLF82_1304.LF82_0831,iNRG857_1313.NRG857_14750 FAD-oxidase_C,FAD_binding_4 k141_36_2 1453501.JELR01000001_gene3245 6.54e-140 405.0 2ASXF@1|root,31ID0@2|Bacteria,1RM30@1224|Proteobacteria,1S8I2@1236|Gammaproteobacteria,46BFQ@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_13122_1 1540257.JQMW01000009_gene3881 1.07e-53 177.0 COG2323@1|root,COG2323@2|Bacteria,1UZYT@1239|Firmicutes,24FP9@186801|Clostridia,36EZV@31979|Clostridiaceae 186801|Clostridia S Protein of unknown function (DUF421) - - - - - - - - - - - - DUF421 k141_10720_1 1219076.N646_1791 1.6e-195 550.0 COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RQMI@1236|Gammaproteobacteria,1XSK4@135623|Vibrionales 135623|Vibrionales NU MSHA biogenesis protein MshG mshG - - ko:K12278 - - - - ko00000,ko02044 - - - T2SSF k141_35700_1 218284.CCDN010000002_gene2744 3.14e-59 205.0 COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,4HE6Q@91061|Bacilli,1ZFF0@1386|Bacillus 91061|Bacilli S ABC-2 family transporter protein - - - ko:K01421 - - - - ko00000 - - - ABC2_membrane_3 k141_23807_1 218284.CCDN010000002_gene2170 4.44e-124 357.0 COG1842@1|root,COG1842@2|Bacteria,1V2MH@1239|Firmicutes,4HGD1@91061|Bacilli,1ZAR1@1386|Bacillus 91061|Bacilli KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription liaH - - - - - - - - - - - PspA_IM30 k141_23807_2 218284.CCDN010000002_gene2171 3.39e-103 303.0 COG4758@1|root,COG4758@2|Bacteria,1V3D0@1239|Firmicutes,4HDIA@91061|Bacilli,1ZDPB@1386|Bacillus 91061|Bacilli S Cell wall-active antibiotics response 4TMS YvqF yvqF - - ko:K11622 ko02020,map02020 - - - ko00000,ko00001 - - - DUF2154 k141_14299_1 218284.CCDN010000005_gene3472 1.03e-166 474.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,4HAEI@91061|Bacilli,1ZAX4@1386|Bacillus 91061|Bacilli E Belongs to the Glu Leu Phe Val dehydrogenases family gluD GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0055114,GO:0071704,GO:1901564 1.4.1.2 ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 - R00243 RC00006,RC02799 ko00000,ko00001,ko01000 - - - ELFV_dehydrog,ELFV_dehydrog_N k141_19048_1 591159.ACEZ01000137_gene2171 1.17e-29 120.0 COG2072@1|root,COG2072@2|Bacteria,2GKYU@201174|Actinobacteria 201174|Actinobacteria P Flavoprotein involved in K transport - - 1.14.13.22 ko:K03379 ko00930,ko01120,ko01220,map00930,map01120,map01220 - R02231,R06622 RC00662,RC01550 ko00000,ko00001,ko01000 - - - FMO-like,NAD_binding_8,Pyr_redox_2,Pyr_redox_3 k141_5983_1 287.DR97_5418 1.01e-89 290.0 COG1835@1|root,COG1835@2|Bacteria,1MV2W@1224|Proteobacteria,1RQS2@1236|Gammaproteobacteria,1YKU5@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria I Acyltransferase family - - - - - - - - - - - - Acyl_transf_3 k141_2408_1 1279017.AQYJ01000022_gene2620 6.81e-105 306.0 28H8Z@1|root,2Z7KS@2|Bacteria,1MW9T@1224|Proteobacteria,1RQV1@1236|Gammaproteobacteria,465P3@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF1282) - - - - - - - - - - - - DUF1282 k141_2408_2 1453501.JELR01000001_gene3234 2.17e-204 571.0 COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,1RSKJ@1236|Gammaproteobacteria,46CN9@72275|Alteromonadaceae 1236|Gammaproteobacteria EH Amino-transferase class IV ilvE - 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_4 k141_28578_1 1294265.JCM21738_3998 1.03e-110 323.0 COG1752@1|root,COG1752@2|Bacteria,1UUVB@1239|Firmicutes,4HDFQ@91061|Bacilli,1ZBCG@1386|Bacillus 91061|Bacilli S esterase of the alpha-beta hydrolase superfamily ylbK GO:0003674,GO:0003824,GO:0016787 - ko:K07001 - - - - ko00000 - - - Patatin k141_28578_2 1294265.JCM21738_3999 3.27e-218 604.0 COG3480@1|root,COG3480@2|Bacteria,1TRUF@1239|Firmicutes,4HBAY@91061|Bacilli,1ZAW6@1386|Bacillus 91061|Bacilli T Belongs to the peptidase S16 family ylbL - - ko:K07177 ko02024,map02024 - - - ko00000,ko00001,ko01002 - - - Lon_C,PDZ_2 k141_37_1 1117379.BABA_18422 4.69e-117 345.0 28MSG@1|root,2Z80Z@2|Bacteria,1TQD3@1239|Firmicutes,4HB4M@91061|Bacilli,1ZQPW@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2515) - - - - - - - - - - - - DUF2515 k141_3609_1 218284.CCDN010000001_gene210 4.48e-88 264.0 COG3773@1|root,COG3773@2|Bacteria,1V43B@1239|Firmicutes,4HJXG@91061|Bacilli,1ZDBK@1386|Bacillus 91061|Bacilli M Cell Wall Hydrolase - - 3.5.1.28 ko:K01449 - - R04112 RC00064,RC00141 ko00000,ko01000 - - - Hydrolase_2,LysM k141_26197_1 1385514.N782_00365 6.63e-80 249.0 COG0659@1|root,COG0659@2|Bacteria,1TT9Y@1239|Firmicutes,4HDPJ@91061|Bacilli,2YBGY@289201|Pontibacillus 91061|Bacilli P Psort location CytoplasmicMembrane, score - - - - - - - - - - - - Xan_ur_permease k141_26197_2 1385511.N783_11695 4.15e-135 392.0 COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,4HAPA@91061|Bacilli,2YBAD@289201|Pontibacillus 91061|Bacilli C Iron-containing alcohol dehydrogenase - - - - - - - - - - - - Fe-ADH k141_30945_1 1132442.KB889752_gene3870 2.12e-25 96.3 COG5566@1|root,COG5566@2|Bacteria,1VEZS@1239|Firmicutes,4HNM8@91061|Bacilli,1ZHZQ@1386|Bacillus 91061|Bacilli S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain yraL - - - - - - - - - - - Mor k141_30945_2 1196031.ALEG01000039_gene1013 1.48e-14 70.9 2C009@1|root,32UHI@2|Bacteria,1V4P1@1239|Firmicutes,4HH50@91061|Bacilli,1ZE0W@1386|Bacillus 91061|Bacilli S FBP C-terminal treble-clef zinc-finger - - - - - - - - - - - - EF-G-binding_N,FBP_C k141_8371_1 218284.CCDN010000008_gene4247 4.31e-94 300.0 COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H9SA@91061|Bacilli,1ZD7B@1386|Bacillus 91061|Bacilli M COG0744 Membrane carboxypeptidase (penicillin-binding protein) pbp1B - 2.4.1.129 ko:K03693,ko:K12551 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase k141_35701_1 1294265.JCM21738_1929 7.77e-33 114.0 2EAWM@1|root,334XV@2|Bacteria,1VJNN@1239|Firmicutes,4IFAK@91061|Bacilli,1ZIVM@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_35701_2 1294265.JCM21738_1928 1.35e-71 218.0 COG0454@1|root,COG0456@2|Bacteria,1TSZY@1239|Firmicutes,4HAYD@91061|Bacilli,1ZD7N@1386|Bacillus 91061|Bacilli K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases yjbC - - - - - - - - - - - Acetyltransf_7 k141_65_1 1454004.AW11_02486 3.38e-26 103.0 COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,2VH6Y@28216|Betaproteobacteria 28216|Betaproteobacteria P phosphate transport system permease pstA - - ko:K02038 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 k141_65_2 1454004.AW11_02485 1.43e-39 139.0 COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,2VI4J@28216|Betaproteobacteria 28216|Betaproteobacteria P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system - - - - - - - - - - - - ABC_tran k141_4821_1 981383.AEWH01000035_gene901 2.13e-48 158.0 COG4463@1|root,COG4463@2|Bacteria,1VAXT@1239|Firmicutes,4HIFT@91061|Bacilli 91061|Bacilli K Belongs to the CtsR family ctsR GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 - ko:K03708 - - - - ko00000,ko03000 - - - CtsR k141_22644_1 1453501.JELR01000001_gene2912 9.61e-140 399.0 COG0476@1|root,COG0476@2|Bacteria,1MW7H@1224|Proteobacteria,1RPJ3@1236|Gammaproteobacteria,466BQ@72275|Alteromonadaceae 1236|Gammaproteobacteria H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 moeB - 2.7.7.73,2.7.7.80 ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07459 RC00043 ko00000,ko00001,ko01000 - - - ThiF k141_2434_2 1280001.BAOA01000026_gene5025 6.09e-17 78.2 COG3655@1|root,COG3655@2|Bacteria,1RBPK@1224|Proteobacteria,1S22Y@1236|Gammaproteobacteria,1XT81@135623|Vibrionales 135623|Vibrionales K Cro/C1-type HTH DNA-binding domain - - - - - - - - - - - - HTH_26 k141_15523_1 218284.CCDN010000008_gene4217 4.24e-118 348.0 COG0773@1|root,COG0773@2|Bacteria,1TQ5H@1239|Firmicutes,4HAR4@91061|Bacilli,1ZB5U@1386|Bacillus 91061|Bacilli M Belongs to the MurCDEF family murC - 6.3.2.8 ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M k141_24999_1 1340434.AXVA01000022_gene3934 4.56e-98 301.0 COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,4HAAP@91061|Bacilli,1ZB4E@1386|Bacillus 91061|Bacilli S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay rnj - - ko:K12574 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - Lactamase_B,Lactamase_B_2,RMMBL k141_10738_1 42565.FP66_08995 2.08e-70 223.0 COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,1RNDK@1236|Gammaproteobacteria,1XI41@135619|Oceanospirillales 135619|Oceanospirillales C Belongs to the citrate synthase family gltA - 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 - - - Citrate_synt k141_15524_1 218284.CCDN010000002_gene2342 2.4e-66 205.0 COG4319@1|root,COG4319@2|Bacteria,1V7MX@1239|Firmicutes,4HIJA@91061|Bacilli 91061|Bacilli S Calcium/calmodulin dependent protein kinase II association domain - - - - - - - - - - - - SnoaL_3 k141_17890_2 1279017.AQYJ01000020_gene1217 4e-265 744.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,464Y3@72275|Alteromonadaceae 1236|Gammaproteobacteria T GGDEF domain - - - - - - - - - - - - 7TMR-DISMED2,EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9 k141_17890_3 1042377.AFPJ01000032_gene2702 8.46e-75 230.0 COG3056@1|root,COG3056@2|Bacteria,1N9MP@1224|Proteobacteria,1SAXB@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Uncharacterized lipoprotein - - - ko:K07286 - - - - ko00000 - - - Lipoprotein_16 k141_17890_4 1247963.JPHU01000001_gene1964 1.21e-20 90.5 COG2847@1|root,COG2847@2|Bacteria 2|Bacteria P Copper chaperone PCu(A)C - - - ko:K07152,ko:K09796 - - - - ko00000,ko03029,ko03110 - - - PCuAC k141_17890_5 1042377.AFPJ01000032_gene2704 1.2e-88 269.0 COG3063@1|root,COG3063@2|Bacteria,1N54A@1224|Proteobacteria,1T30X@1236|Gammaproteobacteria,4683A@72275|Alteromonadaceae 1236|Gammaproteobacteria NU Type IV pilus biogenesis stability protein PilW - - - - - - - - - - - - - k141_17890_6 1279017.AQYJ01000020_gene1221 2.16e-248 703.0 COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,1RPF7@1236|Gammaproteobacteria,46550@72275|Alteromonadaceae 1236|Gammaproteobacteria CO Thiol disulfide interchange protein dsbD - 1.8.1.8 ko:K04084 - - - - ko00000,ko01000,ko03110 5.A.1.1 - - DsbC,DsbD,Thioredoxin_7 k141_17890_7 1286093.C266_00935 4.15e-66 206.0 COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,2VR4Y@28216|Betaproteobacteria,1K5S0@119060|Burkholderiaceae 28216|Betaproteobacteria E Catalyzes a trans-dehydration via an enolate intermediate aroQ - 4.2.1.10 ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03084 RC00848 ko00000,ko00001,ko00002,ko01000 - - - DHquinase_II k141_19065_1 1453501.JELR01000002_gene775 5.95e-47 158.0 COG0134@1|root,COG0134@2|Bacteria,1MW5K@1224|Proteobacteria,1RNYH@1236|Gammaproteobacteria,464E7@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the TrpC family trpC GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48,5.3.1.24 ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03508,R03509 RC00944,RC00945 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_0422 IGPS k141_19065_2 1453501.JELR01000002_gene776 1.16e-174 495.0 COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,1RNXV@1236|Gammaproteobacteria,4661X@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) trpD GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 ko:K00766 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R01073 RC00440 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_0421 Glycos_trans_3N,Glycos_transf_3 k141_19065_3 1279017.AQYJ01000020_gene1236 3.57e-120 345.0 COG0512@1|root,COG0512@2|Bacteria,1MV5Y@1224|Proteobacteria,1RMQW@1236|Gammaproteobacteria,4641F@72275|Alteromonadaceae 1236|Gammaproteobacteria EH COG0512 Anthranilate para-aminobenzoate synthases component II pabA GO:0000162,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006575,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009108,GO:0009308,GO:0009309,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042398,GO:0042401,GO:0042430,GO:0042435,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 2.6.1.85,4.1.3.27 ko:K01658,ko:K01664 ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986,R01716 RC00010,RC01418,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_3095,iEC042_1314.EC042_3623,iECABU_c1320.ECABU_c37840,iECED1_1282.ECED1_4024,iECNA114_1301.ECNA114_3463,iECOK1_1307.ECOK1_3780,iECP_1309.ECP_3451,iECS88_1305.ECS88_3751,iECSF_1327.ECSF_3187,iLF82_1304.LF82_1586,iNRG857_1313.NRG857_16660,iUMN146_1321.UM146_16880,iUTI89_1310.UTI89_C3863,ic_1306.c4135 GATase k141_19065_5 1279017.AQYJ01000020_gene1238 2.15e-297 819.0 COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,1RMSE@1236|Gammaproteobacteria,464I1@72275|Alteromonadaceae 1236|Gammaproteobacteria E Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia trpE - 4.1.3.27 ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_0417 Anth_synt_I_N,Chorismate_bind k141_2436_1 1294265.JCM21738_1343 5.21e-60 186.0 COG2050@1|root,COG2050@2|Bacteria,1V7G2@1239|Firmicutes,4HIIA@91061|Bacilli,1ZGY5@1386|Bacillus 91061|Bacilli Q protein, possibly involved in aromatic compounds catabolism yuxO - - - - - - - - - - - 4HBT k141_2436_2 1294265.JCM21738_1344 6.42e-36 121.0 2EGDT@1|root,33A5P@2|Bacteria,1VKCR@1239|Firmicutes,4HR8T@91061|Bacilli,1ZJBS@1386|Bacillus 91061|Bacilli S Asparagine synthase - - - - - - - - - - - - - k141_66_2 1122194.AUHU01000005_gene960 1.48e-146 424.0 COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,1RQP7@1236|Gammaproteobacteria,466QE@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG3344 Retron-type reverse transcriptase - - - - - - - - - - - - GIIM,RVT_1 k141_1211_1 1453501.JELR01000002_gene471 2.08e-108 325.0 COG0591@1|root,COG0591@2|Bacteria,1MUBI@1224|Proteobacteria,1SYH6@1236|Gammaproteobacteria,465RC@72275|Alteromonadaceae 1236|Gammaproteobacteria E Sodium:solute symporter family VVA1143 - - ko:K03307 - - - - ko00000 2.A.21 - - SSF k141_17891_1 1288826.MSNKSG1_13962 4.72e-107 320.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RM93@1236|Gammaproteobacteria,464KF@72275|Alteromonadaceae 1236|Gammaproteobacteria I Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed - - - - - - - - - - - - Thiolase_C,Thiolase_N k141_22645_1 236097.ADG881_946 3.44e-123 360.0 COG2220@1|root,COG2220@2|Bacteria,1MV20@1224|Proteobacteria,1RN4Z@1236|Gammaproteobacteria,1XH4F@135619|Oceanospirillales 135619|Oceanospirillales S Beta-lactamase superfamily domain - - - - - - - - - - - - Lactamase_B_2 k141_21459_1 1382356.JQMP01000003_gene1709 4.27e-29 115.0 COG2188@1|root,COG2188@2|Bacteria,2GBGB@200795|Chloroflexi,27Z9U@189775|Thermomicrobia 189775|Thermomicrobia K UTRA - - - ko:K03710 - - - - ko00000,ko03000 - - - GntR,UTRA k141_26214_1 218284.CCDN010000001_gene1194 1.49e-74 231.0 COG2265@1|root,COG2265@2|Bacteria,1V4AQ@1239|Firmicutes,4HHBA@91061|Bacilli,1ZCTE@1386|Bacillus 91061|Bacilli J Putative SAM-dependent methyltransferase - - - - - - - - - - - - SAM_MT k141_29754_1 1453501.JELR01000002_gene1217 9.29e-106 308.0 COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,1RP86@1236|Gammaproteobacteria,466E7@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the UPF0758 family radC GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - ko:K03630 - - - - ko00000 - - - RadC k141_67_1 406124.ACPC01000048_gene257 4.84e-64 203.0 COG2761@1|root,COG2761@2|Bacteria,1TZ1N@1239|Firmicutes,4HEBF@91061|Bacilli,1ZD4M@1386|Bacillus 91061|Bacilli Q dithiol-disulfide isomerase involved in polyketide biosynthesis frnE - 5.3.4.1 ko:K01829 - - - - ko00000,ko01000 - - - DSBA k141_34518_1 1279017.AQYJ01000028_gene2026 1.25e-94 282.0 2CHNQ@1|root,2Z7KM@2|Bacteria,1REIJ@1224|Proteobacteria,1S870@1236|Gammaproteobacteria,46BQ7@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_34518_2 1046714.AMRX01000006_gene2431 1.99e-116 344.0 COG5285@1|root,COG5285@2|Bacteria,1MWD5@1224|Proteobacteria,1RSBY@1236|Gammaproteobacteria,466NI@72275|Alteromonadaceae 1236|Gammaproteobacteria Q ectoine hydroxylase ectD - 1.14.11.55 ko:K10674 ko00260,ko01120,map00260,map01120 - R08050 RC00661 ko00000,ko00001,ko01000 - - - PhyH k141_34518_3 649638.Trad_1966 1.14e-88 270.0 COG1814@1|root,COG1814@2|Bacteria,1WMZB@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S VIT family - - - - - - - - - - - - VIT1 k141_34518_4 1042377.AFPJ01000028_gene2214 1.1e-97 293.0 COG3637@1|root,COG3637@2|Bacteria,1N2XM@1224|Proteobacteria,1SIDP@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Outer membrane protein beta-barrel domain - - - - - - - - - - - - OMP_b-brl k141_34518_5 1042377.AFPJ01000028_gene2221 5.29e-113 332.0 COG3637@1|root,COG3637@2|Bacteria,1N2XM@1224|Proteobacteria,1SIDP@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Outer membrane protein beta-barrel domain - - - - - - - - - - - - OMP_b-brl k141_34518_6 1453501.JELR01000002_gene1279 5.06e-68 218.0 COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,1RRTP@1236|Gammaproteobacteria,464NN@72275|Alteromonadaceae 1236|Gammaproteobacteria T GGDEF domain - GO:0003674,GO:0003824,GO:0005488,GO:0008144,GO:0016740,GO:0016772,GO:0016779,GO:0019825,GO:0020037,GO:0036094,GO:0042165,GO:0043167,GO:0043169,GO:0046906,GO:0048037,GO:0052621,GO:0070025,GO:0097159,GO:1901363 2.7.7.65 ko:K13069 - - R08057 - ko00000,ko01000 - - - GGDEF k141_22646_1 713586.KB900536_gene532 4.45e-45 157.0 COG2367@1|root,COG2367@2|Bacteria,1R6KF@1224|Proteobacteria 1224|Proteobacteria V Beta-lactamase enzyme family - - 3.5.2.6 ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 M00627,M00628 R06363 RC01499 ko00000,ko00001,ko00002,ko01000,ko01504 - - - Beta-lactamase2 k141_17893_1 218284.CCDN010000002_gene2947 1.07e-50 166.0 COG4587@1|root,COG4587@2|Bacteria,1TSAN@1239|Firmicutes,4HBVU@91061|Bacilli,1ZBKH@1386|Bacillus 91061|Bacilli S ABC transporter (permease) M1-956 - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_6 k141_34519_1 1042377.AFPJ01000024_gene792 4.13e-49 163.0 COG0810@1|root,COG0810@2|Bacteria 2|Bacteria M energy transducer activity - - - ko:K03646,ko:K03832 - - - - ko00000,ko02000 2.C.1.1,2.C.1.2 - - TonB_C k141_68_1 530564.Psta_3580 2.38e-54 186.0 COG2262@1|root,COG2262@2|Bacteria,2IXH5@203682|Planctomycetes 203682|Planctomycetes S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis hflX - - ko:K03665 - - - - ko00000,ko03009 - - - GTP-bdg_M,GTP-bdg_N,MMR_HSR1 k141_29755_1 42565.FP66_09840 2.16e-156 446.0 COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1MU8P@1224|Proteobacteria,1RQ49@1236|Gammaproteobacteria,1XHR9@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate ribB - 3.5.4.25,4.1.99.12 ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 M00125,M00840 R00425,R07281 RC00293,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 - - - DHBP_synthase,GTP_cyclohydro2 k141_26215_1 218284.CCDN010000003_gene2998 2.19e-54 176.0 COG2318@1|root,COG2318@2|Bacteria,1VAGC@1239|Firmicutes,4HMA9@91061|Bacilli,1ZFRM@1386|Bacillus 91061|Bacilli S DinB superfamily - - - - - - - - - - - - DinB_2 k141_34520_2 795666.MW7_0950 1.42e-43 145.0 COG3832@1|root,COG3832@2|Bacteria,1RCZK@1224|Proteobacteria,2VR7G@28216|Betaproteobacteria,1K1RE@119060|Burkholderiaceae 28216|Betaproteobacteria S Activator of Hsp90 ATPase 1 family protein - - - - - - - - - - - - AHSA1 k141_8399_1 218284.CCDN010000004_gene3078 2.06e-99 309.0 COG3973@1|root,COG3973@2|Bacteria,1TP39@1239|Firmicutes,4H9Y5@91061|Bacilli,1ZAWP@1386|Bacillus 91061|Bacilli L DNA helicase helD_2 - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_19,UvrD-helicase,UvrD_C,UvrD_C_2 k141_9559_1 218284.CCDN010000006_gene3644 5.22e-92 280.0 COG3705@1|root,COG3705@2|Bacteria,1TPZZ@1239|Firmicutes,4HBBA@91061|Bacilli,1ZB4H@1386|Bacillus 91061|Bacilli E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine hisZ - - ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002 - - - tRNA-synt_His k141_20255_1 218284.CCDN010000002_gene2082 3.97e-139 406.0 COG0477@1|root,COG0477@2|Bacteria,1TPHW@1239|Firmicutes,4H9YA@91061|Bacilli,1ZS1D@1386|Bacillus 91061|Bacilli P Major facilitator superfamily - - - - - - - - - - - - MFS_1 k141_33485_2 1492738.FEM21_24950 3.76e-22 96.7 COG3250@1|root,COG3250@2|Bacteria,4NEDP@976|Bacteroidetes,1IMPI@117743|Flavobacteriia,2NUP4@237|Flavobacterium 976|Bacteroidetes G Belongs to the glycosyl hydrolase 2 family - - 3.1.1.53 ko:K05970 - - - - ko00000,ko01000 - - - Glyco_hydro_2_N,SASA k141_4939_1 1042377.AFPJ01000052_gene1555 5.19e-147 443.0 COG3188@1|root,COG3188@2|Bacteria,1PTRC@1224|Proteobacteria,1S047@1236|Gammaproteobacteria 1236|Gammaproteobacteria NU E-set like domain cblC - - - - - - - - - - - CooC_C,TcfC,Usher_TcfC k141_35862_1 218284.CCDN010000002_gene2209 2.81e-64 205.0 COG1744@1|root,COG1744@2|Bacteria,1TPEU@1239|Firmicutes,4HBCY@91061|Bacilli,1ZCTZ@1386|Bacillus 91061|Bacilli S ABC transporter substrate-binding protein PnrA-like - - - ko:K07335 - - - - ko00000 - - - Bmp k141_35862_2 218284.CCDN010000002_gene2208 2.41e-79 254.0 COG0840@1|root,COG0840@2|Bacteria,1UVY9@1239|Firmicutes,4HB1T@91061|Bacilli,1ZD8I@1386|Bacillus 91061|Bacilli NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). yvaQ - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal k141_16862_1 314232.SKA53_12258 2.18e-59 196.0 COG0463@1|root,COG0463@2|Bacteria,1MXC1@1224|Proteobacteria,2TVY5@28211|Alphaproteobacteria,2PA28@245186|Loktanella 28211|Alphaproteobacteria M Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 k141_22812_2 935836.JAEL01000091_gene5312 2.67e-29 105.0 2E4V8@1|root,32ZPI@2|Bacteria,1VEXD@1239|Firmicutes,4HNT1@91061|Bacilli,1ZIYJ@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF1657) - - - - - - - - - - - - DUF1657 k141_26468_1 218284.CCDN010000008_gene4226 7.7e-25 99.4 COG1291@1|root,COG1291@2|Bacteria,1TRH1@1239|Firmicutes,4HAXG@91061|Bacilli,1ZB8I@1386|Bacillus 91061|Bacilli N flagellar motor motP GO:0001539,GO:0005575,GO:0005623,GO:0005886,GO:0006928,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0040011,GO:0044425,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071944,GO:0071973,GO:0071978,GO:0097588 - ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - MotA_ExbB k141_28820_1 218284.CCDN010000001_gene1078 3.42e-37 130.0 COG0517@1|root,COG0517@2|Bacteria,1TR5G@1239|Firmicutes,4H9ZA@91061|Bacilli,1ZD7H@1386|Bacillus 91061|Bacilli S CBS domain - - - - - - - - - - - - CBS k141_34698_1 935839.JAGJ01000010_gene310 1.12e-69 234.0 COG2234@1|root,COG3509@1|root,COG2234@2|Bacteria,COG3509@2|Bacteria,2I0Q0@201174|Actinobacteria,4F57Q@85017|Promicromonosporaceae 201174|Actinobacteria Q Esterase PHB depolymerase - - - - - - - - - - - - Esterase_phd k141_34698_2 1120953.AUBH01000005_gene2328 7.56e-117 351.0 COG0318@1|root,COG0318@2|Bacteria,1MWSD@1224|Proteobacteria,1RQ1C@1236|Gammaproteobacteria,466HP@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ AMP-binding enzyme C-terminal domain - - 6.2.1.48 ko:K02182 - - - - ko00000,ko01000 - - - AMP-binding,AMP-binding_C k141_22813_1 1033810.HLPCO_002516 2.06e-104 315.0 COG0651@1|root,COG0651@2|Bacteria,2NS4P@2323|unclassified Bacteria 2|Bacteria CP Proton-conducting membrane transporter nuoN - 1.6.5.3 ko:K00343,ko:K05568,ko:K12141 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000,ko02000 2.A.63.1,2.A.63.2,3.D.1 - - Proton_antipo_M k141_37042_1 218284.CCDN010000002_gene2577 4.72e-71 225.0 COG4191@1|root,COG4191@2|Bacteria,1UZ9W@1239|Firmicutes,4HDK2@91061|Bacilli,1ZD85@1386|Bacillus 91061|Bacilli T Histidine kinase - - 2.7.13.3 ko:K07697 ko02020,map02020 M00485 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - 5TM-5TMR_LYT,HATPase_c,HisKA k141_37042_2 171693.BN988_02144 4.69e-08 52.8 COG0454@1|root,COG0456@2|Bacteria,1V88N@1239|Firmicutes,4HK32@91061|Bacilli,23MXV@182709|Oceanobacillus 91061|Bacilli K FR47-like protein - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10 k141_12176_1 218284.CCDN010000001_gene1739 2.09e-58 187.0 COG0596@1|root,COG0596@2|Bacteria,1TPEW@1239|Firmicutes,4HC6M@91061|Bacilli,1ZE3I@1386|Bacillus 91061|Bacilli S Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_1 k141_2654_1 981384.AEYW01000022_gene3518 3.56e-58 192.0 COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,2TRZ1@28211|Alphaproteobacteria,4NBFT@97050|Ruegeria 28211|Alphaproteobacteria O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins dnaJ - - ko:K03686 - - - - ko00000,ko03029,ko03110 - - - DnaJ,DnaJ_C,DnaJ_CXXCXGXG k141_20371_1 1294265.JCM21738_3827 6.98e-144 420.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1TR2N@1239|Firmicutes,4H9RR@91061|Bacilli,1ZB2Q@1386|Bacillus 91061|Bacilli EU peptidase yuxL - 3.4.19.1 ko:K01303 - - - - ko00000,ko01000,ko01002 - - - PD40,Peptidase_S9 k141_19231_1 218284.CCDN010000001_gene930 6.87e-93 281.0 COG1459@1|root,COG1459@2|Bacteria,1U00C@1239|Firmicutes,4HGUA@91061|Bacilli,1ZCQK@1386|Bacillus 91061|Bacilli NU COG1459 Type II secretory pathway, component PulF comGB - - ko:K02244 - M00429 - - ko00000,ko00002,ko02044 3.A.14.1 - - T2SSF k141_7381_1 218284.CCDN010000002_gene2263 2.99e-131 379.0 COG0535@1|root,COG0535@2|Bacteria,1TRC8@1239|Firmicutes,4HA9Q@91061|Bacilli,1ZAVK@1386|Bacillus 91061|Bacilli S YfkB-like domain yfkA - - - - - - - - - - - Fer4_12,Fer4_14,Radical_SAM,YfkB k141_23996_1 1294265.JCM21738_599 2.52e-96 284.0 2C7CE@1|root,30872@2|Bacteria,1V67M@1239|Firmicutes,4HHGE@91061|Bacilli,1ZDZH@1386|Bacillus 91061|Bacilli S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) - - - ko:K06345 - - - - ko00000 - - - Spore_YhcN_YlaJ k141_23996_2 1294265.JCM21738_598 1.8e-12 64.7 2DGQY@1|root,32U7R@2|Bacteria,1V83A@1239|Firmicutes,4HKRI@91061|Bacilli,1ZH9Y@1386|Bacillus 91061|Bacilli S BofC C-terminal domain bofC - - ko:K06318 - - - - ko00000 - - - BOFC_N,BofC_C k141_10903_1 1238450.VIBNISOn1_490019 1.39e-49 167.0 28ICJ@1|root,2Z8EW@2|Bacteria,1R4VQ@1224|Proteobacteria,1T1CM@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Nucleoside-specific channel-forming protein, Tsx - - - - - - - - - - - - Channel_Tsx k141_10903_2 745277.GRAQ_02755 2.28e-62 204.0 COG1972@1|root,COG1972@2|Bacteria,1MXXX@1224|Proteobacteria,1RMBX@1236|Gammaproteobacteria,3FFXF@34037|Rahnella 1236|Gammaproteobacteria U Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family yeiM GO:0003674,GO:0005215,GO:0005337,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0015858,GO:0015931,GO:0015932,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:1901264,GO:1901505,GO:1901642 - ko:K03317 - - - - ko00000 2.A.41 - - Gate,Nucleos_tra2_C,Nucleos_tra2_N k141_6302_1 768671.ThimaDRAFT_2075 9.44e-133 396.0 COG3119@1|root,COG3119@2|Bacteria,1NGC8@1224|Proteobacteria,1RRDY@1236|Gammaproteobacteria,1X0G2@135613|Chromatiales 135613|Chromatiales P Sulfatase - - - - - - - - - - - - Sulfatase k141_37043_1 218284.CCDN010000002_gene2866 4.83e-146 431.0 COG1331@1|root,COG1331@2|Bacteria,1U9D9@1239|Firmicutes,4HD6V@91061|Bacilli,1ZF58@1386|Bacillus 91061|Bacilli O Highly conserved protein containing a thioredoxin domain - - - - - - - - - - - - - k141_25205_2 1116375.VEJY3_11690 8.91e-226 624.0 COG3317@1|root,COG3317@2|Bacteria,1MUUK@1224|Proteobacteria,1RN2X@1236|Gammaproteobacteria,1XTAQ@135623|Vibrionales 135623|Vibrionales M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamC - - ko:K07287 - - - - ko00000,ko02000 1.B.33.1 - - Lipoprotein_18 k141_25205_3 1219076.N646_1378 6.27e-184 513.0 COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,1RNH9@1236|Gammaproteobacteria,1XUPA@135623|Vibrionales 135623|Vibrionales E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) dapA GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008840,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS k141_9708_1 555088.DealDRAFT_0165 6.25e-45 152.0 COG2110@1|root,COG2110@2|Bacteria,1TPCU@1239|Firmicutes,24P4W@186801|Clostridia 186801|Clostridia S domain protein - - - - - - - - - - - - - k141_15716_1 218284.CCDN010000009_gene4275 1.39e-130 383.0 COG4856@1|root,COG4856@2|Bacteria,1TSIV@1239|Firmicutes,4HD8Y@91061|Bacilli,1ZB2T@1386|Bacillus 91061|Bacilli S protein conserved in bacteria ybbR GO:0008150,GO:0031279,GO:0031281,GO:0043085,GO:0044093,GO:0045761,GO:0045762,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009 - - - - - - - - - - YbbR k141_13348_1 218284.CCDN010000002_gene2689 3.13e-102 304.0 COG3191@1|root,COG3191@2|Bacteria,1TQHA@1239|Firmicutes,4HAZM@91061|Bacilli,1ZDRB@1386|Bacillus 91061|Bacilli EQ Peptidase family S58 dmpA - 3.4.11.19 ko:K01266 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S58 k141_12177_2 218284.CCDN010000008_gene4255 1.15e-78 246.0 COG0803@1|root,COG0803@2|Bacteria,1TPG7@1239|Firmicutes,4H9UN@91061|Bacilli,1ZC2Z@1386|Bacillus 91061|Bacilli P Belongs to the bacterial solute-binding protein 9 family adcA - - ko:K09815,ko:K09818 ko02010,map02010 M00242,M00243 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 - - ZinT,ZnuA k141_3854_1 218284.CCDN010000001_gene132 2.39e-209 612.0 COG1038@1|root,COG1038@2|Bacteria,1UHP9@1239|Firmicutes,4IS56@91061|Bacilli,1ZC4R@1386|Bacillus 91061|Bacilli C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second pyc - 6.4.1.1 ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 M00173 R00344 RC00040,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,HMGL-like,PYC_OADA k141_3854_2 218284.CCDN010000001_gene133 2.11e-148 427.0 COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,4HAEV@91061|Bacilli,1ZBDZ@1386|Bacillus 91061|Bacilli D Belongs to the SEDS family ftsW - - ko:K03588 ko04112,map04112 - - - ko00000,ko00001,ko02000,ko03036 2.A.103.1 - - FTSW_RODA_SPOVE k141_16867_1 218284.CCDN010000002_gene2555 4.93e-141 407.0 COG2211@1|root,COG2211@2|Bacteria,1UHQ3@1239|Firmicutes,4IS60@91061|Bacilli,1ZS3T@1386|Bacillus 91061|Bacilli G Major Facilitator Superfamily - - - - - - - - - - - - MFS_1,MFS_3 k141_34700_1 1453501.JELR01000002_gene205 7.73e-135 391.0 COG1167@1|root,COG1167@2|Bacteria,1MUUI@1224|Proteobacteria,1RQDS@1236|Gammaproteobacteria,464U4@72275|Alteromonadaceae 1236|Gammaproteobacteria EK Alanine-glyoxylate amino-transferase aspC - - - - - - - - - - - Aminotran_MocR k141_34700_2 1453501.JELR01000002_gene204 5.73e-57 185.0 2DMIH@1|root,32RT1@2|Bacteria,1RDKU@1224|Proteobacteria,1SFC5@1236|Gammaproteobacteria,46CVG@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_18137_1 1444306.JFZC01000096_gene1288 2.41e-13 69.7 2EE4X@1|root,337ZI@2|Bacteria,1VJ70@1239|Firmicutes,4HPMA@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF3168) - - - - - - - - - - - - DUF3168 k141_18137_2 1033738.CAEP01000047_gene525 1.32e-51 169.0 COG5492@1|root,COG5492@2|Bacteria,1VCWC@1239|Firmicutes,4HKF9@91061|Bacilli 91061|Bacilli N domain, Protein - - - - - - - - - - - - Phage_tail_2 k141_21673_1 1453501.JELR01000002_gene1521 1.32e-85 256.0 COG3056@1|root,COG3056@2|Bacteria,1N9MP@1224|Proteobacteria,1SAXB@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Uncharacterized lipoprotein - - - ko:K07286 - - - - ko00000 - - - Lipoprotein_16 k141_28822_1 218284.CCDN010000001_gene263 2.24e-25 102.0 COG1131@1|root,COG1131@2|Bacteria,1TPMQ@1239|Firmicutes,4HDH1@91061|Bacilli,1ZPYP@1386|Bacillus 91061|Bacilli V ABC transporter, ATP-binding protein drrA - - ko:K01990,ko:K09695 ko02010,map02010 M00252,M00254 - - ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.102 - - ABC_tran k141_28822_2 218284.CCDN010000001_gene264 3.25e-235 653.0 COG0842@1|root,COG1511@1|root,COG0842@2|Bacteria,COG1511@2|Bacteria,1V8HM@1239|Firmicutes,4IPM5@91061|Bacilli,1ZRCG@1386|Bacillus 91061|Bacilli V ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 k141_22818_1 1042377.AFPJ01000004_gene396 1.62e-58 194.0 COG0397@1|root,COG0397@2|Bacteria,1MVK3@1224|Proteobacteria,1RNCS@1236|Gammaproteobacteria,4646G@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the UPF0061 (SELO) family ydiU - - ko:K08997 - - - - ko00000 - - - UPF0061 k141_32245_1 177439.DP0186 2.63e-211 618.0 COG1203@1|root,COG1203@2|Bacteria,1MX99@1224|Proteobacteria,42SYD@68525|delta/epsilon subdivisions,2WQZ2@28221|Deltaproteobacteria,2MM0F@213118|Desulfobacterales 28221|Deltaproteobacteria L DEAD-like helicases superfamily - - - ko:K07012 - - - - ko00000,ko01000,ko02048 - - - DEAD,HD,Helicase_C,ResIII k141_32245_3 765912.Thimo_1276 3.69e-213 610.0 COG1468@1|root,COG1518@1|root,COG1468@2|Bacteria,COG1518@2|Bacteria,1MUKK@1224|Proteobacteria,1RNYK@1236|Gammaproteobacteria,1WWHK@135613|Chromatiales 135613|Chromatiales L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette cas1 - - ko:K15342 - - - - ko00000,ko02048,ko03400 - - - Cas_Cas1,Cas_Cas4 k141_25206_1 1242864.D187_003878 1.65e-10 63.5 COG1409@1|root,COG1409@2|Bacteria,1N85S@1224|Proteobacteria,42WZ6@68525|delta/epsilon subdivisions,2WT5K@28221|Deltaproteobacteria 28221|Deltaproteobacteria M Calcineurin-like phosphoesterase - - - - - - - - - - - - Metallophos,Metallophos_C,PKD,Pur_ac_phosph_N k141_6303_2 861299.J421_1491 1.02e-86 272.0 COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,1ZSZ7@142182|Gemmatimonadetes 142182|Gemmatimonadetes CE Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - - - - - - - - - - Fer4_20,Fer4_7,Pyr_redox_2,Pyr_redox_3 k141_29901_2 218284.CCDN010000006_gene3625 1.01e-46 162.0 COG1413@1|root,COG1413@2|Bacteria,1V32S@1239|Firmicutes,4HG23@91061|Bacilli,1ZR97@1386|Bacillus 91061|Bacilli C COG1413 FOG HEAT repeat - - - - - - - - - - - - HEAT,HEAT_2 k141_16869_1 796606.BMMGA3_09615 2.95e-114 337.0 COG0547@1|root,COG0547@2|Bacteria,1TP8U@1239|Firmicutes,4H9KQ@91061|Bacilli,1ZBZ1@1386|Bacillus 91061|Bacilli E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) trpD GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0004425,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R00985,R00986,R01073 RC00010,RC00440,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Glycos_trans_3N,Glycos_transf_3 k141_22819_1 1279017.AQYJ01000018_gene775 2.08e-24 98.6 COG2267@1|root,COG2267@2|Bacteria,1MWF5@1224|Proteobacteria,1RNQR@1236|Gammaproteobacteria,46CDV@72275|Alteromonadaceae 1236|Gammaproteobacteria I Serine aminopeptidase, S33 ynbC GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0008150,GO:0008152,GO:0016020,GO:0016298,GO:0016787,GO:0016788,GO:0044238,GO:0071704 - - - - - - - - - - Hydrolase_4,Methyltransf_20 k141_22819_2 575540.Isop_2476 2.79e-07 53.1 COG0554@1|root,COG0554@2|Bacteria,2IXQW@203682|Planctomycetes 203682|Planctomycetes F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate glpK GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 - R00847 RC00002,RC00017 ko00000,ko00001,ko01000,ko04147 - - - FGGY_C,FGGY_N k141_8556_1 1219076.N646_2937 1.02e-141 408.0 COG1344@1|root,COG1344@2|Bacteria,1MV1N@1224|Proteobacteria,1RN0Y@1236|Gammaproteobacteria,1XSDK@135623|Vibrionales 135623|Vibrionales N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella flaD GO:0005575,GO:0005576,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 - - - ko00000,ko00001,ko02035 - - - Flagellin_C,Flagellin_IN,Flagellin_N k141_10906_1 1499680.CCFE01000010_gene202 4.57e-66 204.0 COG0102@1|root,COG0102@2|Bacteria,1V3HX@1239|Firmicutes,4HG0I@91061|Bacilli,1ZFJA@1386|Bacillus 91061|Bacilli J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly rplM GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02871 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L13 k141_16870_1 218284.CCDN010000007_gene3960 4.49e-98 312.0 COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,1TQAD@1239|Firmicutes,4HCMS@91061|Bacilli,1ZBF6@1386|Bacillus 91061|Bacilli EI Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly icmF GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046906,GO:0046983,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 ko:K11942 - - - - ko00000,ko01000 - - - ArgK,B12-binding,MM_CoA_mutase k141_23999_1 218284.CCDN010000005_gene3291 1.42e-122 366.0 COG1164@1|root,COG1164@2|Bacteria,1TP4P@1239|Firmicutes,4HA7X@91061|Bacilli,1ZCHA@1386|Bacillus 91061|Bacilli E oligoendopeptidase F pepF GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - ko:K08602 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M3,Peptidase_M3_N k141_13349_2 218284.CCDN010000001_gene1915 7.74e-50 159.0 COG1987@1|root,COG1987@2|Bacteria,1VEHF@1239|Firmicutes,4HKVS@91061|Bacilli,1ZI12@1386|Bacillus 91061|Bacilli N Role in flagellar biosynthesis fliQ - - ko:K02420 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - Bac_export_3 k141_3858_1 95619.PM1_0223915 8.14e-77 241.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RM93@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed paaJ GO:0003674,GO:0003824,GO:0006082,GO:0006725,GO:0006805,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016054,GO:0016740,GO:0016746,GO:0016747,GO:0019439,GO:0019748,GO:0019752,GO:0032787,GO:0033554,GO:0033812,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0050896,GO:0051716,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575 2.3.1.16,2.3.1.174,2.3.1.223,2.3.1.9 ko:K00626,ko:K00632,ko:K02615 ko00071,ko00072,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00360,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00087,M00088,M00095,M00113,M00373,M00374,M00375 R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095,R09839 RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955,RC03003 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N k141_21675_1 218284.CCDN010000002_gene2229 1.63e-82 265.0 COG5000@1|root,COG5002@1|root,COG5000@2|Bacteria,COG5002@2|Bacteria,1VS6X@1239|Firmicutes,4HV7W@91061|Bacilli,1ZS6R@1386|Bacillus 91061|Bacilli T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,dCache_1 k141_8557_1 218284.CCDN010000005_gene3434 3.2e-118 352.0 COG0260@1|root,COG0260@2|Bacteria,1TPJZ@1239|Firmicutes,4HAPW@91061|Bacilli,1ZBZU@1386|Bacillus 91061|Bacilli E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides pepA - 3.4.11.1 ko:K01255 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - Peptidase_M17,Peptidase_M17_N k141_22849_1 1121930.AQXG01000011_gene1720 1.93e-78 255.0 COG2132@1|root,COG2132@2|Bacteria,4NE3N@976|Bacteroidetes 976|Bacteroidetes Q Multicopper oxidase - - - - - - - - - - - - Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3 k141_9733_1 218284.CCDN010000007_gene3954 4.11e-127 380.0 COG0247@1|root,COG2181@1|root,COG0247@2|Bacteria,COG2181@2|Bacteria,1TPG1@1239|Firmicutes,4HB2J@91061|Bacilli,1ZBAJ@1386|Bacillus 91061|Bacilli C COG0247 Fe-S oxidoreductase ywjF - - - - - - - - - - - CCG,Fer4_8 k141_8579_1 1385517.N800_07855 4.91e-37 140.0 29TFP@1|root,30ENV@2|Bacteria,1RG86@1224|Proteobacteria,1SGXK@1236|Gammaproteobacteria,1X6ZE@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - k141_13373_1 218284.CCDN010000001_gene980 4.26e-195 560.0 COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,4HADT@91061|Bacilli,1ZAZA@1386|Bacillus 91061|Bacilli KT Transcriptional regulator bkdR - - - - - - - - - - - DapB_N,HTH_8,PAS,Sigma54_activat k141_26530_1 1121937.AUHJ01000020_gene1274 2.3e-44 147.0 COG1846@1|root,COG1846@2|Bacteria,1MZY5@1224|Proteobacteria,1S98B@1236|Gammaproteobacteria,468Y4@72275|Alteromonadaceae 1236|Gammaproteobacteria K helix_turn_helix multiple antibiotic resistance protein - - - - - - - - - - - - MarR k141_4973_1 218284.CCDN010000001_gene1101 8.41e-112 332.0 COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,4HAJ6@91061|Bacilli,1ZAUP@1386|Bacillus 91061|Bacilli S GTPase that plays an essential role in the late steps of ribosome biogenesis der - - ko:K03977 - - - - ko00000,ko03009 - - - KH_dom-like,MMR_HSR1 k141_31195_1 1453501.JELR01000002_gene324 7.3e-242 692.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria,4651V@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec k141_19245_1 1484460.JSWG01000019_gene2081 0.000116 48.5 COG1680@1|root,COG1680@2|Bacteria,4NEEP@976|Bacteroidetes,1I052@117743|Flavobacteriia 976|Bacteroidetes V Beta-lactamase class C and other penicillin binding - - - - - - - - - - - - Beta-lactamase k141_24013_1 218284.CCDN010000001_gene1218 3.1e-61 194.0 COG0454@1|root,COG0456@2|Bacteria,1V4AF@1239|Firmicutes,4HD36@91061|Bacilli,1ZCVH@1386|Bacillus 91061|Bacilli K Acetyltransferase (GNAT) family yodP - 2.3.1.264 ko:K21935 - - R11701 - ko00000,ko01000 - - - Acetyltransf_1,Acetyltransf_9 k141_22850_1 1294265.JCM21738_4261 1.81e-23 98.2 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,4HAN8@91061|Bacilli,1ZBRJ@1386|Bacillus 91061|Bacilli C belongs to the iron- containing alcohol dehydrogenase family adh - 1.1.1.1,1.2.1.10 ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 - R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 ko00000,ko00001,ko01000 - - - Aldedh,Fe-ADH k141_22850_2 349520.PPE_02071 2.71e-05 48.5 COG2323@1|root,COG2323@2|Bacteria,1TRWQ@1239|Firmicutes,4H9VA@91061|Bacilli,26R7K@186822|Paenibacillaceae 91061|Bacilli S membrane yetF1 - - - - - - - - - - - DUF1657,DUF421 k141_9734_1 1403313.AXBR01000026_gene5195 4.24e-17 76.3 COG5652@1|root,COG5652@2|Bacteria,1VZIP@1239|Firmicutes,4I0XH@91061|Bacilli,1ZHW3@1386|Bacillus 91061|Bacilli S VanZ like family - - - - - - - - - - - - VanZ k141_7409_1 935836.JAEL01000080_gene96 3e-14 73.9 COG3069@1|root,COG3069@2|Bacteria,1TPZ6@1239|Firmicutes,4HEQW@91061|Bacilli,1ZDXH@1386|Bacillus 91061|Bacilli C C4-dicarboxylate transmembrane transporter activity - - - - - - - - - - - - - k141_8580_1 1453501.JELR01000001_gene1879 4.41e-99 296.0 COG1533@1|root,COG1533@2|Bacteria,1MW0H@1224|Proteobacteria,1RQNF@1236|Gammaproteobacteria,465H5@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG1533 DNA repair photolyase - - - - - - - - - - - - Radical_SAM k141_35870_1 1453501.JELR01000001_gene2609 1.23e-82 259.0 COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,1RNN9@1236|Gammaproteobacteria,464N3@72275|Alteromonadaceae 1236|Gammaproteobacteria OU COG0616 Periplasmic serine proteases (ClpP class) sohB GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0016020,GO:0019538,GO:0043170,GO:0044238,GO:0044464,GO:0071704,GO:0071944,GO:1901564 - ko:K04774 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S49,Peptidase_S49_N k141_35870_2 1279017.AQYJ01000029_gene3460 4.66e-114 331.0 290UJ@1|root,2ZNGJ@2|Bacteria,1RBSP@1224|Proteobacteria,1S3RZ@1236|Gammaproteobacteria,4675M@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_35870_3 1042377.AFPJ01000031_gene574 1.41e-110 327.0 COG2816@1|root,COG2816@2|Bacteria,1QGCX@1224|Proteobacteria,1RP0Y@1236|Gammaproteobacteria,466XD@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding nudC GO:0003674,GO:0003824,GO:0004551,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030145,GO:0033554,GO:0034641,GO:0035529,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.6.1.22 ko:K03426 ko00760,ko01100,ko04146,map00760,map01100,map04146 - R00103,R03004,R11104 RC00002 ko00000,ko00001,ko01000 - - iAF1260.b3996,iB21_1397.B21_03826,iBWG_1329.BWG_3656,iEC55989_1330.EC55989_4481,iECBD_1354.ECBD_4036,iECB_1328.ECB_03873,iECDH10B_1368.ECDH10B_4185,iECDH1ME8569_1439.ECDH1ME8569_3856,iECD_1391.ECD_03873,iECIAI1_1343.ECIAI1_4211,iECO103_1326.ECO103_4745,iECO111_1330.ECO111_4813,iECO26_1355.ECO26_5105,iECSE_1348.ECSE_4284,iECW_1372.ECW_m4355,iEKO11_1354.EKO11_4325,iETEC_1333.ETEC_4256,iEcDH1_1363.EcDH1_3998,iEcE24377_1341.EcE24377A_4539,iEcHS_1320.EcHS_A4230,iEcolC_1368.EcolC_4029,iJO1366.b3996,iPC815.YPO3736,iSSON_1240.SSON_4169,iUMNK88_1353.UMNK88_4837,iWFL_1372.ECW_m4355,iY75_1357.Y75_RS17065,iYL1228.KPN_04378 NUDIX,NUDIX-like,zf-NADH-PPase k141_35870_4 1453501.JELR01000001_gene2612 7.94e-271 757.0 COG2198@1|root,COG2198@2|Bacteria,1QY43@1224|Proteobacteria,1S0ZB@1236|Gammaproteobacteria,4641V@72275|Alteromonadaceae 1236|Gammaproteobacteria T Histidine kinase fimL - - - - - - - - - - - Hpt k141_35870_5 1042377.AFPJ01000031_gene572 1.48e-126 375.0 COG3067@1|root,COG3067@2|Bacteria,1MV0F@1224|Proteobacteria,1RPE3@1236|Gammaproteobacteria,464PD@72275|Alteromonadaceae 1236|Gammaproteobacteria P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons nhaB GO:0003674,GO:0005215,GO:0005451,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0006873,GO:0006885,GO:0008150,GO:0008324,GO:0009987,GO:0010035,GO:0010038,GO:0010226,GO:0015075,GO:0015077,GO:0015078,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015491,GO:0015672,GO:0016020,GO:0019725,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030004,GO:0030641,GO:0034220,GO:0035725,GO:0042221,GO:0042592,GO:0044464,GO:0045851,GO:0046873,GO:0048878,GO:0050801,GO:0050896,GO:0051179,GO:0051234,GO:0051452,GO:0051453,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0098771,GO:0099516,GO:1902600 - ko:K03314 - - - - ko00000,ko02000 2.A.34.1 - iECP_1309.ECP_1229,iLF82_1304.LF82_1485,iNRG857_1313.NRG857_06055,iUTI89_1310.UTI89_C1372 NhaB k141_6320_1 1294265.JCM21738_2523 1.56e-175 494.0 COG2202@1|root,COG4191@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,1VCNJ@1239|Firmicutes,4HVBX@91061|Bacilli,1ZS41@1386|Bacillus 91061|Bacilli T Histidine kinase - - 2.7.13.3 ko:K07698 ko02020,map02020 M00485 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS,PAS_3,PAS_9 k141_6320_2 997296.PB1_03320 1.06e-06 49.7 COG1232@1|root,COG1232@2|Bacteria,1TQ6W@1239|Firmicutes,4HAUG@91061|Bacilli,1ZANK@1386|Bacillus 91061|Bacilli H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX hemY - 1.3.3.15,1.3.3.4 ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03222,R04178 RC00885 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS09325 Amino_oxidase k141_33518_1 1348114.OM33_14295 1.79e-08 56.2 COG0845@1|root,COG5569@1|root,COG0845@2|Bacteria,COG5569@2|Bacteria,1MVAS@1224|Proteobacteria,1RPBZ@1236|Gammaproteobacteria,2PZP9@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family cusB - - ko:K07798 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.6.1.4,8.A.1 - - CusF_Ec,HlyD_D23,HlyD_D4 k141_2670_1 42565.FP66_00205 3.31e-88 266.0 COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,1RM7M@1236|Gammaproteobacteria,1XIB9@135619|Oceanospirillales 135619|Oceanospirillales J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA rsmH - 2.1.1.199 ko:K03438 - - - - ko00000,ko01000,ko03009 - - - Methyltransf_5 k141_2670_2 42565.FP66_00200 3.81e-55 179.0 COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,1RM7U@1236|Gammaproteobacteria,1XHFQ@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA rsmI - 2.1.1.198 ko:K07056 - - - - ko00000,ko01000,ko03009 - - - TP_methylase k141_31196_1 768066.HELO_3594 2.26e-87 270.0 COG2148@1|root,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,1RMMN@1236|Gammaproteobacteria,1XHA3@135619|Oceanospirillales 135619|Oceanospirillales M COG2148 Sugar transferases involved in lipopolysaccharide synthesis wcaJ - 2.7.8.40 ko:K03606,ko:K21303 ko05111,map05111 - - - ko00000,ko00001,ko01000,ko01003,ko01005 - - - Bac_transf,CoA_binding_3 k141_10026_2 1294265.JCM21738_3760 2.01e-74 232.0 COG0489@1|root,COG0489@2|Bacteria,1TQ34@1239|Firmicutes,4HAW4@91061|Bacilli,1ZC2E@1386|Bacillus 91061|Bacilli D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP mrp GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K03593 - - - - ko00000,ko03029,ko03036 - - - FeS_assembly_P,ParA k141_15883_1 1294265.JCM21738_587 6.11e-121 359.0 COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,4HAB7@91061|Bacilli,1ZDHC@1386|Bacillus 91061|Bacilli S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid spoVB - - ko:K06409 - - - - ko00000,ko02000 2.A.66.2.14 - - Polysacc_synt,Polysacc_synt_C k141_19485_1 1111135.HMPREF1248_1385 8.37e-59 198.0 COG0008@1|root,COG0008@2|Bacteria,2GJJS@201174|Actinobacteria,4CV46@84998|Coriobacteriia 84998|Coriobacteriia J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) gltX - 6.1.1.17 ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 - - - tRNA-synt_1c k141_10027_1 218284.CCDN010000006_gene3539 3.02e-90 273.0 COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HB3V@91061|Bacilli,1ZB8V@1386|Bacillus 91061|Bacilli IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - ko:K00666 - - - - ko00000,ko01000,ko01004 - - - AMP-binding,AMP-binding_C k141_15884_1 565045.NOR51B_2004 8.23e-50 172.0 COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,1RN0E@1236|Gammaproteobacteria,1J5K7@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Barrel-sandwich domain of CusB or HlyD membrane-fusion macA - - ko:K02005 - - - - ko00000 - - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 k141_10028_1 218284.CCDN010000001_gene1300 8.8e-59 186.0 COG2318@1|root,COG2318@2|Bacteria,1V6UF@1239|Firmicutes,4HIPX@91061|Bacilli,1ZD6H@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF664) - - - - - - - - - - - - DUF664 k141_25488_1 350688.Clos_1809 1.06e-19 83.6 COG0454@1|root,COG0454@2|Bacteria,1V3SX@1239|Firmicutes,24G4B@186801|Clostridia,36I67@31979|Clostridiaceae 186801|Clostridia K acetyltransferase - - - - - - - - - - - - Acetyltransf_1 k141_25488_2 153948.NAL212_1483 8.88e-40 147.0 COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,2VI1K@28216|Betaproteobacteria,371PP@32003|Nitrosomonadales 28216|Betaproteobacteria FP Ppx GppA phosphatase ppx - 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 - R03409 RC00002 ko00000,ko00001,ko01000 - - - Ppx-GppA k141_36027_1 1042377.AFPJ01000004_gene367 1.35e-80 242.0 COG1664@1|root,COG1664@2|Bacteria,1ND4H@1224|Proteobacteria,1SF92@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Polymer-forming cytoskeletal - - - - - - - - - - - - Bactofilin k141_17082_1 1294265.JCM21738_2212 1.41e-51 163.0 29JW2@1|root,306TD@2|Bacteria,1U0BH@1239|Firmicutes,4I9NA@91061|Bacilli,1ZISQ@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2524) ytzC - - - - - - - - - - - DUF2524 k141_34925_2 322710.Avin_18600 1.41e-62 198.0 COG0819@1|root,COG0819@2|Bacteria,1MVA0@1224|Proteobacteria,1RSHF@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Long-chain fatty acid--CoA ligase - - - - - - - - - - - - Haem_oxygenas_2 k141_27659_1 1288826.MSNKSG1_00531 1.07e-33 127.0 COG0711@1|root,COG0711@2|Bacteria,1R6C0@1224|Proteobacteria,1S4NA@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) - - - ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_B,OSCP k141_27659_2 1288826.MSNKSG1_00536 2.06e-34 120.0 COG0636@1|root,COG0636@2|Bacteria,1NAIE@1224|Proteobacteria,1SA80@1236|Gammaproteobacteria 1236|Gammaproteobacteria C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation - - - ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_C k141_12530_1 997296.PB1_07287 1.73e-58 193.0 COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,4H9MW@91061|Bacilli,1ZBKI@1386|Bacillus 91061|Bacilli L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids dnaA GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - ko:K02313 ko02020,ko04112,map02020,map04112 - - - ko00000,ko00001,ko03032,ko03036 - - - Bac_DnaA,Bac_DnaA_C,DnaA_N k141_11207_1 1116375.VEJY3_13250 7.37e-113 327.0 COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,1RMS5@1236|Gammaproteobacteria,1XTR0@135623|Vibrionales 135623|Vibrionales H Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate pdxJ GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 ko:K03474 ko00750,ko01100,map00750,map01100 M00124 R05838 RC01476 ko00000,ko00001,ko00002,ko01000 - - - PdxJ k141_11207_2 1116375.VEJY3_13245 3.55e-70 213.0 COG0736@1|root,COG0736@2|Bacteria,1MZBF@1224|Proteobacteria,1S98P@1236|Gammaproteobacteria,1XXAM@135623|Vibrionales 135623|Vibrionales I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein acpS GO:0003674,GO:0003824,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008897,GO:0009058,GO:0016740,GO:0016772,GO:0016780,GO:0044238,GO:0071704,GO:1901576 2.7.8.7 ko:K00997 ko00770,map00770 - R01625 RC00002 ko00000,ko00001,ko01000 - - - ACPS k141_11207_3 1116375.VEJY3_13240 0.0 1686.0 COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1XV4F@135623|Vibrionales 135623|Vibrionales T Histidine kinase barA - 2.7.13.3 ko:K07678 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 M00475 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - DUF2222,HATPase_c,HisKA,Hpt,Response_reg k141_8865_1 218284.CCDN010000001_gene233 8.19e-91 279.0 COG0165@1|root,COG0165@2|Bacteria,1TNZ6@1239|Firmicutes,4HB24@91061|Bacilli,1ZD3C@1386|Bacillus 91061|Bacilli E argininosuccinate lyase argH GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01086 RC00445,RC00447 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ASL_C2,Lyase_1 k141_21878_1 1123261.AXDW01000001_gene1414 9.35e-62 201.0 COG0416@1|root,COG0416@2|Bacteria,1MVM3@1224|Proteobacteria,1RM7R@1236|Gammaproteobacteria,1X3M1@135614|Xanthomonadales 135614|Xanthomonadales I Fatty acid synthesis protein - - - - - - - - - - - - FA_synthesis k141_19507_1 1294265.JCM21738_4211 4.04e-119 344.0 COG1120@1|root,COG1120@2|Bacteria,1TP2Q@1239|Firmicutes,4HADG@91061|Bacilli,1ZBMI@1386|Bacillus 91061|Bacilli HP ABC transporter yusV - 3.6.3.34 ko:K02013 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 - - ABC_tran k141_5280_1 1453501.JELR01000001_gene2941 2.92e-34 132.0 COG3525@1|root,COG3525@2|Bacteria,1MVDE@1224|Proteobacteria,1RMNI@1236|Gammaproteobacteria,465K7@72275|Alteromonadaceae 1236|Gammaproteobacteria G Putative carbohydrate binding domain chb - 3.2.1.52 ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 M00079 R00022,R06004,R11316 RC00049 ko00000,ko00001,ko00002,ko01000,ko03110 - GH20 - CHB_HEX,CHB_HEX_C,Glyco_hydro_20,Glyco_hydro_20b k141_33815_1 760192.Halhy_2453 7e-44 157.0 COG1668@1|root,COG1668@2|Bacteria,4NFSZ@976|Bacteroidetes,1IR1T@117747|Sphingobacteriia 976|Bacteroidetes CP ABC-type Na efflux pump, permease component natB - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 k141_13701_1 1453501.JELR01000001_gene3087 2.74e-50 160.0 COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,1S8U1@1236|Gammaproteobacteria,467QQ@72275|Alteromonadaceae 1236|Gammaproteobacteria J COG1544 Ribosome-associated protein Y (PSrp-1) yhbH GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - ko:K05808 - - - - ko00000,ko03009 - - - Ribosomal_S30AE k141_11236_3 218284.CCDN010000001_gene833 1.22e-21 85.5 29WT8@1|root,30IEM@2|Bacteria,1U55R@1239|Firmicutes,4I1FH@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - k141_11236_4 1117108.PAALTS15_01562 1.34e-97 290.0 COG1351@1|root,COG1351@2|Bacteria,1TRHD@1239|Firmicutes,4HTFB@91061|Bacilli,26S56@186822|Paenibacillaceae 91061|Bacilli F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - 2.1.1.148 ko:K03465 ko00240,ko00670,ko01100,map00240,map00670,map01100 - R06613 RC00022,RC00332 ko00000,ko00001,ko01000 - - - Thy1 k141_26860_1 1236973.JCM9157_1071 1.52e-126 373.0 COG3314@1|root,COG3314@2|Bacteria,1TR35@1239|Firmicutes,4HAB6@91061|Bacilli,1ZARZ@1386|Bacillus 91061|Bacilli S protein conserved in bacteria - - - - - - - - - - - - Gate k141_12560_1 218284.CCDN010000001_gene1808 1.16e-118 365.0 COG0249@1|root,COG0249@2|Bacteria,1TPRJ@1239|Firmicutes,4HA63@91061|Bacilli,1ZB93@1386|Bacillus 91061|Bacilli L that it carries out the mismatch recognition step. This protein has a weak ATPase activity mutS GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K03555 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V k141_30094_1 218284.CCDN010000008_gene4142 2.5e-139 405.0 COG1169@1|root,COG1169@2|Bacteria,1TSRT@1239|Firmicutes,4H9K8@91061|Bacilli,1ZB3V@1386|Bacillus 91061|Bacilli HQ Isochorismate synthase menF - 5.4.4.2 ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 M00116 R01717 RC00588 ko00000,ko00001,ko00002,ko01000 - - - Chorismate_bind k141_24185_1 1294265.JCM21738_367 2.81e-62 198.0 COG1052@1|root,COG1052@2|Bacteria,1UI1W@1239|Firmicutes,4HA71@91061|Bacilli,1ZAZJ@1386|Bacillus 91061|Bacilli CH Dipicolinate synthase subunit A dpaA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0016618,GO:0030267,GO:0044424,GO:0044444,GO:0044464,GO:0055114 - ko:K06410 - - - - ko00000 - - iYO844.BSU16730 2-Hacid_dh_C,AlaDh_PNT_C,DpaA_N k141_7567_1 218284.CCDN010000001_gene1398 3.23e-63 196.0 COG4326@1|root,COG4326@2|Bacteria,1UBJH@1239|Firmicutes,4IMZA@91061|Bacilli,1ZIXE@1386|Bacillus 91061|Bacilli S SpoOM protein - - - - - - - - - - - - Spo0M k141_5281_1 218284.CCDN010000004_gene3039 6.24e-31 119.0 COG3428@1|root,COG3428@2|Bacteria,1TSRJ@1239|Firmicutes,4HB8P@91061|Bacilli,1ZBIF@1386|Bacillus 91061|Bacilli S Membrane ydbT - - ko:K08981 - - - - ko00000 - - - bPH_2 k141_5281_2 218284.CCDN010000004_gene3040 3.08e-82 246.0 COG3402@1|root,COG3402@2|Bacteria,1VFTS@1239|Firmicutes,4HGMB@91061|Bacilli,1ZG99@1386|Bacillus 91061|Bacilli S Bacterial PH domain ydbS - - ko:K09167 - - - - ko00000 - - - bPH_2 k141_25510_2 1453501.JELR01000002_gene1184 2.93e-105 308.0 COG0500@1|root,COG0500@2|Bacteria,1RDHE@1224|Proteobacteria,1S3U0@1236|Gammaproteobacteria,46D40@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Protein of unknown function (DUF938) - - - - - - - - - - - - DUF938 k141_25510_3 1453501.JELR01000002_gene1183 5.29e-56 181.0 COG3022@1|root,COG3022@2|Bacteria,1MUAF@1224|Proteobacteria,1RMTD@1236|Gammaproteobacteria,4644D@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the UPF0246 family yaaA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0033194,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:1901700 - ko:K09861 - - - - ko00000 - - - H2O2_YaaD k141_27672_1 1385514.N782_14760 2.59e-79 255.0 COG1193@1|root,COG1193@2|Bacteria,1TQWB@1239|Firmicutes,4HAHW@91061|Bacilli,2Y8ZS@289201|Pontibacillus 91061|Bacilli L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity mutS1 - - ko:K07456 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_V k141_2823_1 1034347.CAHJ01000010_gene1973 1.91e-67 214.0 COG0324@1|root,COG0324@2|Bacteria,1TPSC@1239|Firmicutes,4HAVW@91061|Bacilli,1ZBX9@1386|Bacillus 91061|Bacilli J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) miaA GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 - R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 - - - IPPT k141_13702_2 626939.HMPREF9443_01466 6.13e-05 46.6 COG1314@1|root,COG1314@2|Bacteria,1VKK3@1239|Firmicutes,4H5QY@909932|Negativicutes 909932|Negativicutes U Preprotein translocase SecG subunit secG - - ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecG k141_8867_1 42565.FP66_14055 3.47e-106 332.0 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,1RMPV@1236|Gammaproteobacteria,1XHDT@135619|Oceanospirillales 135619|Oceanospirillales F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdA - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN k141_6477_1 1042377.AFPJ01000053_gene1505 1.97e-234 671.0 COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,1RNKN@1236|Gammaproteobacteria,463YS@72275|Alteromonadaceae 1236|Gammaproteobacteria CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit mnhA - - ko:K05565 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - DUF4040,MnhB,Proton_antipo_M,Proton_antipo_N k141_6477_2 1120963.KB894502_gene1361 7.57e-36 134.0 COG3004@1|root,COG3004@2|Bacteria,1MW15@1224|Proteobacteria,1RNDE@1236|Gammaproteobacteria,2Q26G@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria P ) H( ) antiporter that extrudes sodium in exchange for external protons nhaA - - ko:K03313 - - - - ko00000,ko02000 2.A.33.1 - - Na_H_antiport_1 k141_32442_1 223926.28805721 1.84e-152 436.0 COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,1RND5@1236|Gammaproteobacteria,1XU6J@135623|Vibrionales 135623|Vibrionales CH COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases ubiF - - ko:K03184 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R06146,R08775 RC01254 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,FAD_binding_3,SE k141_14669_1 406124.ACPC01000019_gene2752 6.12e-57 184.0 COG4430@1|root,COG4430@2|Bacteria,1V41W@1239|Firmicutes,4HDKN@91061|Bacilli,1ZC25@1386|Bacillus 91061|Bacilli S Bacteriocin-protection, YdeI or OmpD-Associated - - - - - - - - - - - - OmdA k141_14669_2 218284.CCDN010000002_gene2279 3.96e-161 458.0 COG0842@1|root,COG0842@2|Bacteria,1UYSF@1239|Firmicutes,4HEYE@91061|Bacilli,1ZCKQ@1386|Bacillus 91061|Bacilli V ABC-2 type transporter - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane,ABC2_membrane_3 k141_13703_1 398511.BpOF4_10145 1.15e-99 299.0 COG0552@1|root,COG0552@2|Bacteria,1TR66@1239|Firmicutes,4HDEI@91061|Bacilli,1ZDQ2@1386|Bacillus 91061|Bacilli U protein localization to endoplasmic reticulum - - - - - - - - - - - - - k141_37256_2 218284.CCDN010000002_gene2143 2.49e-282 776.0 COG2610@1|root,COG2610@2|Bacteria,1TQ14@1239|Firmicutes,4HB0Y@91061|Bacilli,1ZAYI@1386|Bacillus 91061|Bacilli EG COG2610 H gluconate symporter and related permeases gntU - - ko:K03299,ko:K06156 - - - - ko00000,ko02000 2.A.8,2.A.8.1.8 - - GntP_permease k141_24186_1 1279017.AQYJ01000023_gene3092 2.79e-148 443.0 COG0620@1|root,COG0620@2|Bacteria,1MUI9@1224|Proteobacteria,1RMBA@1236|Gammaproteobacteria,465YA@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation metE GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0032259,GO:0034641,GO:0035999,GO:0036211,GO:0042084,GO:0042085,GO:0042558,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0050667,GO:0051186,GO:0071704,GO:0140096,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - iE2348C_1286.E2348C_4130,iECO103_1326.ECO103_4334,iECO111_1330.ECO111_4657,iECO26_1355.ECO26_4756,iECW_1372.ECW_m4131,iEKO11_1354.EKO11_4528,iPC815.YPO3788,iWFL_1372.ECW_m4131 Meth_synt_1,Meth_synt_2 k141_30095_1 218284.CCDN010000001_gene801 1.84e-121 361.0 COG0457@1|root,COG0705@1|root,COG0457@2|Bacteria,COG0705@2|Bacteria,1TQXT@1239|Firmicutes,4HCDF@91061|Bacilli,1ZBV7@1386|Bacillus 91061|Bacilli O membrane protein (homolog of Drosophila rhomboid) gluP - 3.4.21.105 ko:K19225 - - - - ko00000,ko01000,ko01002 - - - Rhomboid,TPR_2,TPR_8 k141_10070_1 218284.CCDN010000002_gene2883 6.99e-100 304.0 COG0737@1|root,COG0737@2|Bacteria,1TQCW@1239|Firmicutes,4HEVJ@91061|Bacilli,1ZM3P@1386|Bacillus 91061|Bacilli F 5'-nucleotidase, C-terminal domain - - - - - - - - - - - - 5_nucleotid_C,Metallophos k141_25512_1 1231057.AMGD01000024_gene2966 1.08e-97 305.0 COG2225@1|root,COG2225@2|Bacteria,1UA0Z@1239|Firmicutes,4HBPG@91061|Bacilli,26EDC@186818|Planococcaceae 91061|Bacilli C Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA glcB - 2.3.3.9 ko:K01638 ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200 M00012 R00472 RC00004,RC00308,RC02747 ko00000,ko00001,ko00002,ko01000 - - - Malate_synthase k141_18394_3 491915.Aflv_2336 1.06e-09 57.0 COG0526@1|root,COG0526@2|Bacteria,1V3YC@1239|Firmicutes,4HJ8N@91061|Bacilli,21WYA@150247|Anoxybacillus 91061|Bacilli CO Thioredoxin bdbA - - - - - - - - - - - Thioredoxin k141_11239_1 1307436.PBF_21933 9.13e-38 139.0 COG3935@1|root,COG3935@2|Bacteria,1TSHD@1239|Firmicutes,4HIGY@91061|Bacilli,1ZGCU@1386|Bacillus 91061|Bacilli L Replication initiation and membrane attachment - - - - - - - - - - - - DnaB_2 k141_27673_1 1042377.AFPJ01000028_gene2288 1.52e-52 182.0 COG0457@1|root,COG0457@2|Bacteria,1N0A9@1224|Proteobacteria,1RZSZ@1236|Gammaproteobacteria,466AY@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0457 FOG TPR repeat - - - - - - - - - - - - TPR_16,TPR_2,TPR_7 k141_36044_2 218284.CCDN010000001_gene1089 3.87e-93 283.0 COG2959@1|root,COG2959@2|Bacteria,1TT9K@1239|Firmicutes,4HBM9@91061|Bacilli,1ZB4M@1386|Bacillus 91061|Bacilli H sporulation protein ypeB - - ko:K06313 - - - - ko00000 - - - PepSY,YPEB k141_5283_1 218284.CCDN010000001_gene269 3.27e-15 69.7 COG0640@1|root,COG0640@2|Bacteria,1VA6G@1239|Firmicutes,4HKYT@91061|Bacilli,1ZGXI@1386|Bacillus 91061|Bacilli K transcriptional czrA - - ko:K22043 - - - - ko00000,ko03000 - - - HTH_5 k141_5283_2 218284.CCDN010000001_gene270 7.59e-75 244.0 COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,4H9SP@91061|Bacilli,1ZAPS@1386|Bacillus 91061|Bacilli P COG2217 Cation transport ATPase cadA - 3.6.3.3,3.6.3.5 ko:K01534 - - - - ko00000,ko01000 3.A.3.6 - - E1-E2_ATPase,HMA,Hydrolase k141_28985_1 218284.CCDN010000001_gene1455 7.42e-69 213.0 COG0352@1|root,COG0352@2|Bacteria,1V3ZR@1239|Firmicutes,4HH1E@91061|Bacilli,1ZFNE@1386|Bacillus 91061|Bacilli H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) thiE GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 ko:K00788 ko00730,ko01100,map00730,map01100 M00127 R03223,R10712 RC00224,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU38290 TMP-TENI k141_28985_2 218284.CCDN010000001_gene1454 7.26e-65 204.0 COG0351@1|root,COG0351@2|Bacteria,1TQ4A@1239|Firmicutes,4HAAH@91061|Bacilli,1ZCQT@1386|Bacillus 91061|Bacilli H Phosphomethylpyrimidine kinase thiD - 2.7.1.49,2.7.4.7 ko:K00941 ko00730,ko01100,map00730,map01100 M00127 R03471,R04509 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Phos_pyr_kin k141_23175_1 218284.CCDN010000007_gene3796 4.42e-165 471.0 COG0486@1|root,COG0486@2|Bacteria,1TPJF@1239|Firmicutes,4HA06@91061|Bacilli,1ZBTZ@1386|Bacillus 91061|Bacilli S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 mnmE - - ko:K03650 - - R08701 RC00053,RC00209,RC00870 ko00000,ko01000,ko03016 - - - MMR_HSR1,MnmE_helical,TrmE_N k141_10071_1 501479.ACNW01000101_gene95 1.62e-38 133.0 COG1376@1|root,COG1376@2|Bacteria,1MVYT@1224|Proteobacteria,2U60K@28211|Alphaproteobacteria 28211|Alphaproteobacteria S ErfK YbiS YcfS YnhG family protein - - - - - - - - - - - - YkuD k141_10071_2 314265.R2601_15317 6.58e-14 67.0 COG3118@1|root,COG3118@2|Bacteria,1RHUA@1224|Proteobacteria,2U97P@28211|Alphaproteobacteria 28211|Alphaproteobacteria O Thioredoxin trxC - 1.8.1.8 ko:K03672 - - - - ko00000,ko01000,ko03110 - - - Thioredoxin k141_31344_1 913865.DOT_6265 3.11e-54 176.0 2DZYA@1|root,32VN2@2|Bacteria,1VA7J@1239|Firmicutes,25E2C@186801|Clostridia,2669P@186807|Peptococcaceae 186801|Clostridia - - - - - - - - - - - - - - - k141_21879_2 1453501.JELR01000001_gene2028 9.72e-50 171.0 COG3047@1|root,COG3047@2|Bacteria 2|Bacteria - - ompW - - ko:K07275 - - - - ko00000 - - - OmpW k141_8868_2 218284.CCDN010000002_gene2048 2.37e-46 151.0 COG0526@1|root,COG0526@2|Bacteria,1VFUD@1239|Firmicutes,4HNQS@91061|Bacilli,1ZJBR@1386|Bacillus 91061|Bacilli CO Thioredoxin ydfQ - - - - - - - - - - - Thioredoxin k141_25513_2 1219076.N646_4134 5.55e-86 269.0 COG2176@1|root,COG2176@2|Bacteria,1MUZD@1224|Proteobacteria,1RPGP@1236|Gammaproteobacteria,1XUHP@135623|Vibrionales 135623|Vibrionales L VRR_NUC - - - - - - - - - - - - VRR_NUC k141_5284_1 218284.CCDN010000001_gene728 1.6e-64 210.0 COG0860@1|root,COG0860@2|Bacteria,1TSFS@1239|Firmicutes,4HACZ@91061|Bacilli,1ZAV0@1386|Bacillus 91061|Bacilli M stage II sporulation protein P spoIIP - - ko:K06385 - - - - ko00000 - - - SpoIIP k141_12562_1 644966.Tmar_1480 2.51e-30 119.0 COG1319@1|root,COG1319@2|Bacteria,1TQA5@1239|Firmicutes,248WI@186801|Clostridia 186801|Clostridia C Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM - - 1.2.5.3 ko:K03519 - - R11168 RC02800 ko00000,ko01000 - - - CO_deh_flav_C,FAD_binding_5 k141_30096_2 1149133.ppKF707_3754 6.61e-08 57.4 COG3437@1|root,COG3437@2|Bacteria,1P1A3@1224|Proteobacteria,1S2RH@1236|Gammaproteobacteria 1236|Gammaproteobacteria T response regulator - - - - - - - - - - - - HD_5,Response_reg k141_7569_1 935836.JAEL01000063_gene2141 5.44e-172 489.0 COG1509@1|root,COG1509@2|Bacteria,1TQQZ@1239|Firmicutes,4HE2P@91061|Bacilli,1ZBET@1386|Bacillus 91061|Bacilli E lysine 2,3-aminomutase kamA - 5.4.3.2 ko:K01843 ko00310,map00310 - R00461 RC00303 ko00000,ko00001,ko01000 - - - Fer4_12,Fer4_14,LAM_C,Radical_SAM k141_18416_8 68199.JNZO01000025_gene5822 2.58e-09 59.3 2DMV7@1|root,32TWY@2|Bacteria,2IMXB@201174|Actinobacteria 201174|Actinobacteria S Protein of unknown function (DUF3168) - - - - - - - - - - - - DUF3168 k141_18416_9 1334046.AYTB01000008_gene2319 1.39e-55 179.0 COG5492@1|root,COG5492@2|Bacteria,1VCWC@1239|Firmicutes,4HKF9@91061|Bacilli 91061|Bacilli N domain, Protein - - - - - - - - - - - - Phage_tail_2 k141_30100_1 223926.28807522 0.0 966.0 COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,1XUSD@135623|Vibrionales 135623|Vibrionales NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB pilB - - ko:K02652 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE,T2SSE_N k141_30100_2 1116375.VEJY3_13035 1.19e-262 723.0 COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RNV0@1236|Gammaproteobacteria,1XV78@135623|Vibrionales 135623|Vibrionales U COG1459 Type II secretory pathway, component PulF pilC GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009297,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0016043,GO:0022607,GO:0030030,GO:0030031,GO:0032940,GO:0033036,GO:0042886,GO:0043711,GO:0044085,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0098776 - ko:K02653 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSF k141_19534_1 42565.FP66_00715 3.94e-173 486.0 COG0679@1|root,COG0679@2|Bacteria,1PINE@1224|Proteobacteria,1S1F1@1236|Gammaproteobacteria,1XS4C@135619|Oceanospirillales 135619|Oceanospirillales S Membrane transport protein - - - ko:K07088 - - - - ko00000 - - - Mem_trans k141_17117_1 997296.PB1_07477 8.71e-75 239.0 COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,4HA31@91061|Bacilli,1ZBNF@1386|Bacillus 91061|Bacilli O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain yyxA - 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Trypsin_2 k141_5319_1 1042377.AFPJ01000023_gene657 4.5e-125 405.0 COG1361@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4932@2|Bacteria,1QUEG@1224|Proteobacteria 1224|Proteobacteria M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - - - - - - - - - - SdrD_B k141_24178_8 1116375.VEJY3_03840 4.74e-76 227.0 COG2142@1|root,COG2142@2|Bacteria,1MZR9@1224|Proteobacteria,1S9TS@1236|Gammaproteobacteria,1XX9X@135623|Vibrionales 135623|Vibrionales C Membrane-anchoring subunit of succinate dehydrogenase (SDH) sdhD - - ko:K00242 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173 R02164 RC00045 ko00000,ko00001,ko00002 - - - Sdh_cyt k141_24178_9 1116375.VEJY3_03845 0.0 1187.0 COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,1RMU2@1236|Gammaproteobacteria,1XUJA@135623|Vibrionales 135623|Vibrionales C Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily sdhA - 1.3.5.1,1.3.5.4 ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C k141_24178_10 1219076.N646_2998 1.4e-175 488.0 COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,1RNWR@1236|Gammaproteobacteria,1XSXW@135623|Vibrionales 135623|Vibrionales C Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family sdhB - 1.3.5.1,1.3.5.4 ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - Fer2_3,Fer4_17 k141_24178_11 1116375.VEJY3_03855 0.0 1858.0 COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,1RN8K@1236|Gammaproteobacteria,1XUQD@135623|Vibrionales 135623|Vibrionales C COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes sucA - 1.2.4.2 ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R00621,R01933,R01940,R03316,R08549 RC00004,RC00027,RC00627,RC02743,RC02833,RC02883 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr k141_24178_12 1116375.VEJY3_03860 2.19e-271 744.0 COG0508@1|root,COG0508@2|Bacteria,1MUJD@1224|Proteobacteria,1RME0@1236|Gammaproteobacteria,1XTKP@135623|Vibrionales 135623|Vibrionales C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) sucB - 2.3.1.61 ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R02570,R02571,R08549 RC00004,RC02727,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding k141_24178_13 1219076.N646_3001 1.68e-273 749.0 COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,1RMSU@1236|Gammaproteobacteria,1XTU2@135623|Vibrionales 135623|Vibrionales F Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit sucC GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 6.2.1.5 ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp_2,Ligase_CoA k141_24178_15 1280001.BAOA01000047_gene1733 2.77e-158 447.0 COG1108@1|root,COG1108@2|Bacteria,1MVC2@1224|Proteobacteria,1RPYF@1236|Gammaproteobacteria,1XTAW@135623|Vibrionales 135623|Vibrionales P COG1108 ABC-type Mn2 Zn2 transport systems, permease components znuB - - ko:K09816 ko02010,map02010 M00242 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15.3,3.A.1.15.5 - - ABC-3 k141_24178_16 223926.28805838 4.73e-155 439.0 COG1121@1|root,COG1121@2|Bacteria,1MUDW@1224|Proteobacteria,1RPJT@1236|Gammaproteobacteria,1XTI4@135623|Vibrionales 135623|Vibrionales P Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system znuC GO:0000041,GO:0003674,GO:0003824,GO:0005215,GO:0005385,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0042623,GO:0042626,GO:0043492,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662 - ko:K09817 ko02010,map02010 M00242 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.15.3,3.A.1.15.5 - - ABC_tran k141_24178_17 1280001.BAOA01000047_gene1735 1.71e-154 440.0 COG4531@1|root,COG4531@2|Bacteria,1QTTI@1224|Proteobacteria,1RMRJ@1236|Gammaproteobacteria,1XT4D@135623|Vibrionales 135623|Vibrionales P COG4531 ABC-type Zn2 transport system, periplasmic component surface adhesin znuA - - ko:K09815 ko02010,map02010 M00242 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15.3,3.A.1.15.5 - - ZnuA k141_24178_18 1116375.VEJY3_03890 0.0 1844.0 COG2207@1|root,COG3292@1|root,COG2207@2|Bacteria,COG3292@2|Bacteria,1R5Q9@1224|Proteobacteria,1S7F8@1236|Gammaproteobacteria,1XUWH@135623|Vibrionales 135623|Vibrionales KT Transcriptional regulator - - - ko:K19693 - - - - ko00000,ko03000 - - - HTH_18,Reg_prop k141_24178_19 1116375.VEJY3_03895 6.04e-43 140.0 COG1918@1|root,COG1918@2|Bacteria,1Q29A@1224|Proteobacteria,1SGFM@1236|Gammaproteobacteria,1XYYK@135623|Vibrionales 135623|Vibrionales P Fe2 transport system protein A feoA - - ko:K04758 - - - - ko00000,ko02000 - - - FeoA k141_24178_20 223926.28805844 0.0 1339.0 COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,1RME9@1236|Gammaproteobacteria,1XSYA@135623|Vibrionales 135623|Vibrionales P transporter of a GTP-driven Fe(2 ) uptake system feoB - - ko:K04759 - - - - ko00000,ko02000 9.A.8.1 - - FeoB_C,FeoB_N,Gate k141_24178_21 1219076.N646_3009 1.08e-41 137.0 2EGR8@1|root,33AHD@2|Bacteria,1QTRG@1224|Proteobacteria,1SUI3@1236|Gammaproteobacteria,1XYXP@135623|Vibrionales 135623|Vibrionales S FeoC like transcriptional regulator VV1042 - - ko:K10123 - - - - ko00000,ko02000 - - - FeoC k141_24178_22 1116375.VEJY3_03910 3.54e-98 285.0 COG0537@1|root,COG0537@2|Bacteria,1MZVD@1224|Proteobacteria,1S9D9@1236|Gammaproteobacteria,1XX0J@135623|Vibrionales 135623|Vibrionales FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases - - - - - - - - - - - - HIT k141_24178_23 1116375.VEJY3_03915 0.0 1091.0 COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,1RPRC@1236|Gammaproteobacteria,1XSVJ@135623|Vibrionales 135623|Vibrionales J Arginyl-tRNA synthetase argS GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d k141_24178_24 1280001.BAOA01000047_gene1743 4.57e-120 345.0 COG3102@1|root,COG3102@2|Bacteria,1RB98@1224|Proteobacteria,1SI78@1236|Gammaproteobacteria,1XUTF@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria - - - ko:K09907 - - - - ko00000 - - - YecM k141_34958_1 796606.BMMGA3_11010 7.37e-110 326.0 COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,4HAHH@91061|Bacilli,1ZBRQ@1386|Bacillus 91061|Bacilli M Belongs to the peptidase S11 family dacB GO:0003674,GO:0003824,GO:0004175,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.16.4 ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - PBP5_C,Peptidase_S11 k141_11232_1 866895.HBHAL_3208 3.06e-26 102.0 COG0454@1|root,COG0456@2|Bacteria,1U521@1239|Firmicutes,4HBEJ@91061|Bacilli,3NFRE@45667|Halobacillus 91061|Bacilli K Acetyltransferase (GNAT) family ykwB - - - - - - - - - - - Acetyltransf_1 k141_624_1 1294265.JCM21738_3777 1.95e-71 226.0 COG0642@1|root,COG2205@2|Bacteria,1UPFH@1239|Firmicutes,4IV44@91061|Bacilli,1ZG3M@1386|Bacillus 91061|Bacilli T Membrane-associated sensor domain - - - - - - - - - - - - MASE3 k141_624_2 1120973.AQXL01000079_gene114 7.57e-08 53.9 COG2855@1|root,COG2855@2|Bacteria,1TQYA@1239|Firmicutes,4HCCP@91061|Bacilli,279RS@186823|Alicyclobacillaceae 91061|Bacilli S Conserved hypothetical protein 698 - - - - - - - - - - - - Cons_hypoth698 k141_36041_1 218284.CCDN010000009_gene4315 2.98e-206 585.0 COG0601@1|root,COG1173@1|root,COG0601@2|Bacteria,COG1173@2|Bacteria,1V21B@1239|Firmicutes,4HDPU@91061|Bacilli,1ZEQ7@1386|Bacillus 91061|Bacilli EP Binding-protein-dependent transport system inner membrane component - - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1,Peptidase_M1 k141_32437_1 1116375.VEJY3_16716 1.85e-107 316.0 COG4302@1|root,COG4302@2|Bacteria,1MWQI@1224|Proteobacteria,1RQ2T@1236|Gammaproteobacteria,1XVCN@135623|Vibrionales 135623|Vibrionales H Ethanolamine ammonia-lyase light chain (EutC) - - 4.3.1.7 ko:K03736 ko00564,ko01100,map00564,map01100 - R00749 RC00370 ko00000,ko00001,ko01000 - - - EutC k141_8860_1 218284.CCDN010000001_gene1593 1.74e-105 311.0 COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,4HA2S@91061|Bacilli,1ZAUS@1386|Bacillus 91061|Bacilli P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components dppB GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0022857,GO:0051179,GO:0051234,GO:0055085 - ko:K16200 ko02010,map02010 M00566 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.2 - iYO844.BSU12930 BPD_transp_1 k141_26855_1 1042377.AFPJ01000042_gene1024 2.45e-14 73.2 COG1249@1|root,COG1249@2|Bacteria,1PS20@1224|Proteobacteria 1224|Proteobacteria C FAD dependent oxidoreductase - - - - - - - - - - - - FAD_oxidored k141_31340_1 240015.ACP_2928 1.77e-60 211.0 COG0085@1|root,COG0085@2|Bacteria,3Y36G@57723|Acidobacteria,2JIQM@204432|Acidobacteriia 204432|Acidobacteriia K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoB - 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 k141_15893_1 218284.CCDN010000007_gene3814 2.55e-167 483.0 COG3887@1|root,COG3887@2|Bacteria,1TPGP@1239|Firmicutes,4HBVH@91061|Bacilli,1ZCB0@1386|Bacillus 91061|Bacilli T signaling protein consisting of a modified GGDEF domain and a DHH domain yybT - - - - - - - - - - - DHH,DHHA1 k141_34959_1 1279017.AQYJ01000028_gene2428 7.19e-55 183.0 COG2207@1|root,COG2207@2|Bacteria,1MX23@1224|Proteobacteria,1RRXM@1236|Gammaproteobacteria 1236|Gammaproteobacteria K AraC family transcriptional regulator - - - - - - - - - - - - Arabinose_bd,HTH_18 k141_24179_1 218284.CCDN010000003_gene3016 4.18e-126 371.0 COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,4H9X4@91061|Bacilli,1ZAVI@1386|Bacillus 91061|Bacilli J Belongs to the class-II aminoacyl-tRNA synthetase family lysS - 6.1.1.6 ko:K04567 ko00970,map00970 M00359,M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2,tRNA_anti-codon k141_37251_1 218284.CCDN010000002_gene2244 3.17e-115 337.0 COG0457@1|root,COG0457@2|Bacteria,1V074@1239|Firmicutes,4HEC7@91061|Bacilli 91061|Bacilli S Tetratricopeptide repeat M1-509 - - ko:K07705 ko02020,map02020 M00492 - - ko00000,ko00001,ko00002,ko02022 - - - TPR_8 k141_14666_1 1453501.JELR01000001_gene2480 2.05e-94 285.0 COG1472@1|root,COG1472@2|Bacteria,1MVAJ@1224|Proteobacteria,1RMQF@1236|Gammaproteobacteria,463YX@72275|Alteromonadaceae 1236|Gammaproteobacteria G Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides nagZ GO:0000270,GO:0003674,GO:0003824,GO:0004553,GO:0004563,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006807,GO:0008150,GO:0008152,GO:0009254,GO:0009273,GO:0009987,GO:0015929,GO:0016787,GO:0016798,GO:0030203,GO:0042546,GO:0043170,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901564 3.2.1.52 ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 M00628 R00022,R05963,R07809,R07810,R10831 RC00049 ko00000,ko00001,ko00002,ko01000 - - iSFV_1184.SFV_1127,iUMN146_1321.UM146_11790 Glyco_hydro_3 k141_14666_2 1279017.AQYJ01000025_gene736 3.03e-202 566.0 COG0668@1|root,COG0668@2|Bacteria,1MXD2@1224|Proteobacteria,1RNUB@1236|Gammaproteobacteria,464I7@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0668 Small-conductance mechanosensitive channel ynaI GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0042802,GO:0044464,GO:0071944 - ko:K16052 - - - - ko00000,ko02000 1.A.23.4 - - MS_channel k141_14666_3 1279017.AQYJ01000025_gene735 5.94e-48 152.0 COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,46CT6@72275|Alteromonadaceae 1236|Gammaproteobacteria K Cold shock protein domain - - - ko:K03704 - - - - ko00000,ko03000 - - - CSD k141_14666_4 1042377.AFPJ01000007_gene1908 6.8e-248 686.0 COG5505@1|root,COG5505@2|Bacteria,1MW87@1224|Proteobacteria,1RQPZ@1236|Gammaproteobacteria,46A9F@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF819) - - - - - - - - - - - - DUF819 k141_14666_5 1042377.AFPJ01000007_gene1907 2.56e-08 62.0 2EC19@1|root,3360G@2|Bacteria,1N87W@1224|Proteobacteria,1S7E3@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Peptidoglycan-binding protein, CsiV pgs1 - - - - - - - - - - - CsiV k141_14666_6 1279017.AQYJ01000025_gene733 0.0 1192.0 COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,1RNCU@1236|Gammaproteobacteria,464IX@72275|Alteromonadaceae 1236|Gammaproteobacteria L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd GO:0000715,GO:0000716,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006283,GO:0006289,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008094,GO:0008150,GO:0008152,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0015616,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031326,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0043175,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051276,GO:0051716,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF k141_10063_1 316274.Haur_3527 9.16e-09 61.6 COG1366@1|root,COG2202@1|root,COG3290@1|root,COG1366@2|Bacteria,COG2202@2|Bacteria,COG3290@2|Bacteria,2GA9X@200795|Chloroflexi,376XC@32061|Chloroflexia 32061|Chloroflexia T PFAM Sulfate transporter antisigma-factor antagonist STAS - - - ko:K17763 - - - - ko00000,ko03021 - - - PAS_3,PAS_4,STAS k141_19537_1 1169144.KB910940_gene2537 2.45e-118 360.0 COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4H9ZK@91061|Bacilli,1ZCFC@1386|Bacillus 91061|Bacilli S ABC transporter - - - - - - - - - - - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn k141_24223_2 218284.CCDN010000010_gene4326 1.07e-148 422.0 COG0726@1|root,COG0726@2|Bacteria,1UZJN@1239|Firmicutes,4IPMR@91061|Bacilli,1ZBAU@1386|Bacillus 91061|Bacilli G xylanase chitin deacetylase pdaB - - - - - - - - - - - Polysacc_deac_1 k141_15920_1 1051646.VITU9109_04127 5.37e-81 241.0 COG4628@1|root,COG4628@2|Bacteria,1N7DG@1224|Proteobacteria,1S2VZ@1236|Gammaproteobacteria,1XX0U@135623|Vibrionales 135623|Vibrionales S DNA-binding protein VF530 - - - - - - - - - - - - VF530 k141_15920_2 1116375.VEJY3_18311 5.44e-69 211.0 COG1959@1|root,COG1959@2|Bacteria,1RGVW@1224|Proteobacteria,1S7TG@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator - - - - - - - - - - - - Rrf2 k141_15920_3 1116375.VEJY3_18306 5.67e-67 205.0 2B2HD@1|root,31V2D@2|Bacteria,1N0R5@1224|Proteobacteria,1S7IS@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_23197_1 997296.PB1_16579 1.65e-136 400.0 COG1524@1|root,COG1524@2|Bacteria,1UY6W@1239|Firmicutes,4HDR4@91061|Bacilli,1ZDAM@1386|Bacillus 91061|Bacilli S Type I phosphodiesterase / nucleotide pyrophosphatase - - - - - - - - - - - - Phosphodiest k141_1622_1 218284.CCDN010000001_gene379 1.9e-26 99.8 2BPSH@1|root,32IJT@2|Bacteria,1UAV1@1239|Firmicutes,4IM7V@91061|Bacilli,1ZJFD@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_5323_1 1380408.AVGH01000024_gene1629 6.11e-43 147.0 COG2186@1|root,COG2186@2|Bacteria,1V2TU@1239|Firmicutes,4HDHI@91061|Bacilli 91061|Bacilli K Transcriptional yvfI - - ko:K05799 - - - - ko00000,ko03000 - - - FCD,GntR k141_13720_1 218284.CCDN010000008_gene4146 3.17e-94 288.0 COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HACS@91061|Bacilli,1ZB6H@1386|Bacillus 91061|Bacilli H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily menE - 6.2.1.26 ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R04030 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - AMP-binding,AMP-binding_C k141_30103_1 1405.DJ92_1241 2.79e-26 105.0 2DZ9Y@1|root,32V70@2|Bacteria,1VA6H@1239|Firmicutes,4HKSG@91061|Bacilli,1ZHSJ@1386|Bacillus 91061|Bacilli S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) yhcN - - - - - - - - - - - Spore_YhcN_YlaJ k141_10103_1 218284.CCDN010000001_gene1961 2.04e-95 278.0 COG0219@1|root,COG0219@2|Bacteria,1V3GW@1239|Firmicutes,4HFNY@91061|Bacilli,1ZFKH@1386|Bacillus 91061|Bacilli J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily cspR - 2.1.1.207 ko:K03216 - - - - ko00000,ko01000,ko03016 - - - SpoU_methylase k141_10103_2 218284.CCDN010000001_gene1962 1.88e-124 358.0 2DB72@1|root,2Z7JI@2|Bacteria,1UR4B@1239|Firmicutes,4HCE4@91061|Bacilli,1ZC8T@1386|Bacillus 91061|Bacilli S Putative amidase domain yhbB - - - - - - - - - - - Amidase_6 k141_4133_1 796606.BMMGA3_04270 5.84e-21 84.0 2C5QJ@1|root,33C5U@2|Bacteria,1VK5Y@1239|Firmicutes,4HR2R@91061|Bacilli,1ZIUX@1386|Bacillus 91061|Bacilli S Spore germination protein gerPD - - ko:K06302 - - - - ko00000 - - - - k141_4133_2 218284.CCDN010000005_gene3234 1.54e-55 179.0 2EBJR@1|root,335K6@2|Bacteria,1VF1J@1239|Firmicutes,4HNKG@91061|Bacilli,1ZI2K@1386|Bacillus 91061|Bacilli S Spore germination protein gerPC - - ko:K06301 - - - - ko00000 - - - GerPC k141_24224_1 665952.HMPREF1015_00900 6.41e-63 209.0 COG4191@1|root,COG4191@2|Bacteria,1VCNJ@1239|Firmicutes,4HVBX@91061|Bacilli,1ZS41@1386|Bacillus 91061|Bacilli T Histidine kinase - - 2.7.13.3 ko:K02491 ko02020,map02020 M00485 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS,PAS_3,PAS_9 k141_31360_1 218284.CCDN010000001_gene1141 2.05e-10 62.0 COG0847@1|root,COG1199@1|root,COG0847@2|Bacteria,COG1199@2|Bacteria,1TQHQ@1239|Firmicutes,4HB2Y@91061|Bacilli,1ZAWI@1386|Bacillus 91061|Bacilli L helicase involved in DNA repair and perhaps also replication dinG - 3.6.4.12 ko:K03722 - - - - ko00000,ko01000,ko03400 - - - DEAD,Helicase_C_2,RNase_T,ResIII k141_31360_2 218284.CCDN010000001_gene1140 8.37e-78 232.0 COG0853@1|root,COG0853@2|Bacteria,1V6NQ@1239|Firmicutes,4HIV1@91061|Bacilli,1ZG9V@1386|Bacillus 91061|Bacilli H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine panD - 4.1.1.11 ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 M00119 R00489 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Asp_decarbox k141_18422_1 1453501.JELR01000002_gene713 3.34e-123 365.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,465NN@72275|Alteromonadaceae 1236|Gammaproteobacteria C belongs to the aldehyde dehydrogenase family aldA - 1.2.1.3 ko:K00128,ko:K00138 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00711,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_2828_2 1042377.AFPJ01000032_gene2804 1.66e-159 452.0 COG0688@1|root,COG0688@2|Bacteria,1MVT4@1224|Proteobacteria,1RN1U@1236|Gammaproteobacteria,4656J@72275|Alteromonadaceae 1236|Gammaproteobacteria I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) psd - 4.1.1.65 ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 M00093 R02055 RC00299 ko00000,ko00001,ko00002,ko01000 - - - PS_Dcarbxylase k141_2828_3 1279017.AQYJ01000027_gene1578 1.28e-210 595.0 COG2206@1|root,COG2206@2|Bacteria,1MW7F@1224|Proteobacteria,1RPEZ@1236|Gammaproteobacteria,465PC@72275|Alteromonadaceae 1236|Gammaproteobacteria T Domain of unknown function (DUF3391) - - - - - - - - - - - - DUF3391,HD_5 k141_2828_6 1279017.AQYJ01000027_gene1581 0.0 2580.0 COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,1RN2W@1236|Gammaproteobacteria,465BS@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0067 Glutamate synthase domain 1 gltB GO:0003674,GO:0003824,GO:0004355,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045181,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14 ko:K00265 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - iBWG_1329.BWG_2914,iECDH10B_1368.ECDH10B_3387,iECDH1ME8569_1439.EcDH1_0495,iEcDH1_1363.EcDH1_0495,iPC815.YPO3557 GATase_2,GXGXG,Glu_syn_central,Glu_synthase k141_2828_7 1279017.AQYJ01000027_gene1582 5.65e-61 198.0 COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,1RN4I@1236|Gammaproteobacteria,46412@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) aroB GO:0000166,GO:0003674,GO:0003824,GO:0003856,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0051287,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.4 ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03083 RC00847 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b3389,iBWG_1329.BWG_3080,iECDH10B_1368.ECDH10B_3564,iECDH1ME8569_1439.ECDH1ME8569_3268,iECNA114_1301.ECNA114_3486,iEcDH1_1363.EcDH1_0324,iJO1366.b3389,iJR904.b3389,iY75_1357.Y75_RS20275 DHQ_synthase k141_21897_1 414684.RC1_0729 8.26e-13 63.5 COG1841@1|root,COG1841@2|Bacteria,1PU2S@1224|Proteobacteria,2UF55@28211|Alphaproteobacteria,2JTU5@204441|Rhodospirillales 204441|Rhodospirillales J Ribosomal protein L30 rpmD - - ko:K02907 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L30 k141_21897_2 379066.GAU_0890 8.5e-69 218.0 COG0098@1|root,COG0098@2|Bacteria,1ZTHD@142182|Gemmatimonadetes 142182|Gemmatimonadetes J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body rpsE - - ko:K02988 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S5,Ribosomal_S5_C k141_21897_3 1297617.JPJD01000013_gene902 6.23e-06 45.4 COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,24JCS@186801|Clostridia,269CK@186813|unclassified Clostridiales 186801|Clostridia J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance rplR - - ko:K02881 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L18p k141_8894_2 379066.GAU_2667 2.04e-39 135.0 COG2363@1|root,COG2363@2|Bacteria,1ZUWK@142182|Gemmatimonadetes 142182|Gemmatimonadetes S Protein of unknown function (DUF423) - - - - - - - - - - - - DUF423 k141_10104_1 1340434.AXVA01000008_gene3653 3.79e-36 130.0 COG1177@1|root,COG1177@2|Bacteria,1V0UU@1239|Firmicutes,4HD56@91061|Bacilli,1ZF0W@1386|Bacillus 91061|Bacilli E Binding-protein-dependent transport system inner membrane component - - - ko:K02053 ko02024,map02024 M00193 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11 - - BPD_transp_1 k141_10104_2 1163398.AJJP01000124_gene4682 8.59e-29 112.0 COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,1RMTS@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Part of the ABC transporter complex FbpABC involved in Fe(3 ) ions import. Responsible for energy coupling to the transport system - - - ko:K02052 ko02024,map02024 M00193 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11 - - ABC_tran,TOBE_2 k141_27693_1 1294265.JCM21738_5475 7.86e-109 314.0 COG0640@1|root,COG3860@1|root,COG0640@2|Bacteria,COG3860@2|Bacteria,1V1C5@1239|Firmicutes,4HG15@91061|Bacilli,1ZEHF@1386|Bacillus 91061|Bacilli K Uncharacterized protein conserved in bacteria (DUF2087) - - - - - - - - - - - - DUF2087,HTH_20,HTH_5 k141_34997_1 1071073.KI530537_gene2076 4.77e-38 138.0 COG1372@1|root,COG1372@2|Bacteria,1VPYF@1239|Firmicutes,4HSTN@91061|Bacilli,1ZEPN@1386|Bacillus 91061|Bacilli L LAGLIDADG-like domain - - - - - - - - - - - - LAGLIDADG_3 k141_6494_1 1042377.AFPJ01000031_gene573 1.47e-144 426.0 COG2198@1|root,COG2198@2|Bacteria,1QY43@1224|Proteobacteria,1S0ZB@1236|Gammaproteobacteria,4641V@72275|Alteromonadaceae 1236|Gammaproteobacteria T Histidine kinase fimL - - - - - - - - - - - Hpt k141_24225_2 1129794.C427_2251 2.11e-18 83.6 28IBE@1|root,2Z8DX@2|Bacteria,1NC7D@1224|Proteobacteria,1RP6N@1236|Gammaproteobacteria,4641D@72275|Alteromonadaceae 1236|Gammaproteobacteria S Putative amidoligase enzyme - - - - - - - - - - - - Amidoligase_2 k141_23198_1 1042377.AFPJ01000024_gene819 1.73e-37 136.0 COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,1RN0W@1236|Gammaproteobacteria,464SX@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0006 Xaa-Pro aminopeptidase pepP - 3.4.11.9 ko:K01262 - - - - ko00000,ko01000,ko01002 - - - AMP_N,Peptidase_M24 k141_23198_2 1453501.JELR01000002_gene699 4.08e-101 296.0 COG3079@1|root,COG3079@2|Bacteria,1N7W0@1224|Proteobacteria,1SCPW@1236|Gammaproteobacteria,4689M@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the UPF0149 family ygfB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K09895 - - - - ko00000 - - - UPF0149 k141_12576_1 218284.CCDN010000001_gene201 7.21e-50 159.0 COG1925@1|root,COG1925@2|Bacteria,1VA0R@1239|Firmicutes,4HKGA@91061|Bacilli,1ZHX7@1386|Bacillus 91061|Bacilli G phosphocarrier protein HPr ptsH GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0043610,GO:0044424,GO:0044464,GO:0050789,GO:0065007 - ko:K11189 - - - - ko00000,ko02000 4.A.2.1 - - PTS-HPr k141_645_1 218284.CCDN010000001_gene1362 1.24e-121 366.0 COG1193@1|root,COG1193@2|Bacteria,1TQWB@1239|Firmicutes,4HAHW@91061|Bacilli,1ZC6C@1386|Bacillus 91061|Bacilli L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity mutS1 - - ko:K07456 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_V k141_645_2 218284.CCDN010000001_gene1363 1.04e-121 351.0 COG0428@1|root,COG0428@2|Bacteria,1V1UC@1239|Firmicutes,4HGST@91061|Bacilli,1ZCIQ@1386|Bacillus 91061|Bacilli P transporter - - - ko:K07238 - - - - ko00000,ko02000 2.A.5.5 - - Zip k141_32468_1 796606.BMMGA3_09025 3.16e-40 151.0 COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,4HA3G@91061|Bacilli,1ZAVY@1386|Bacillus 91061|Bacilli T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,PAS,PAS_3,PAS_9 k141_28998_2 1283337.B0ZSJ3_BPHA1 2.34e-79 241.0 4QCX5@10239|Viruses,4QVAG@35237|dsDNA viruses no RNA stage,4QPPT@28883|Caudovirales,4QJXH@10662|Myoviridae 10662|Myoviridae S Glycosyl hydrolase 108 - - - - - - - - - - - - - k141_21898_1 252305.OB2597_06645 5.94e-41 150.0 COG1479@1|root,COG3586@1|root,COG1479@2|Bacteria,COG3586@2|Bacteria,1NRBC@1224|Proteobacteria,2TSI9@28211|Alphaproteobacteria,2PF6N@252301|Oceanicola 28211|Alphaproteobacteria S Protein of unknown function DUF262 - - - - - - - - - - - - DUF1524,DUF262 k141_19540_1 218284.CCDN010000002_gene2252 3.58e-104 316.0 COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,4HBUS@91061|Bacilli,1ZB01@1386|Bacillus 91061|Bacilli EH Belongs to the TPP enzyme family ydaP - 1.2.3.3 ko:K00158 ko00620,ko01100,map00620,map01100 - R00207 RC02745 ko00000,ko00001,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N k141_37269_1 1168065.DOK_10647 2.32e-70 229.0 COG0651@1|root,COG0651@2|Bacteria,1MURB@1224|Proteobacteria,1RQBG@1236|Gammaproteobacteria,1J4RJ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria CP Proton-conducting membrane transporter - - - ko:K05568 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - Proton_antipo_M k141_37269_2 1042377.AFPJ01000024_gene707 3.01e-249 696.0 COG0651@1|root,COG0651@2|Bacteria,1QU5Z@1224|Proteobacteria,1T20X@1236|Gammaproteobacteria,464H1@72275|Alteromonadaceae 1236|Gammaproteobacteria CP Proton-conducting membrane transporter - - - ko:K05568 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - Proton_antipo_M,Proton_antipo_N k141_37269_3 1168065.DOK_10637 2.1e-32 115.0 2EAIM@1|root,334MN@2|Bacteria,1N6XM@1224|Proteobacteria,1SF6C@1236|Gammaproteobacteria,1J73Y@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_37269_4 1453501.JELR01000002_gene527 7.7e-315 868.0 COG0651@1|root,COG0651@2|Bacteria,1MV6V@1224|Proteobacteria,1RQK5@1236|Gammaproteobacteria,464XB@72275|Alteromonadaceae 1236|Gammaproteobacteria CP Proton-conducting membrane transporter - - - ko:K05568 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - Proton_antipo_M k141_37269_5 1042377.AFPJ01000007_gene1819 2.63e-78 241.0 COG1309@1|root,COG1309@2|Bacteria,1N659@1224|Proteobacteria,1RPXN@1236|Gammaproteobacteria,4682Q@72275|Alteromonadaceae 1236|Gammaproteobacteria K MAATS-type transcriptional repressor, C-terminal region acrR GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042493,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0045892,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K03577 - M00647 - - ko00000,ko00002,ko03000 - - - TetR_C_2,TetR_N k141_37269_6 701347.Entcl_3327 3.92e-16 80.9 COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,1RPI1@1236|Gammaproteobacteria,3X09D@547|Enterobacter 1236|Gammaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family acrA GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0006869,GO:0008150,GO:0010876,GO:0015238,GO:0015711,GO:0015718,GO:0015721,GO:0015849,GO:0015850,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0032991,GO:0033036,GO:0042221,GO:0042493,GO:0042597,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0046942,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098796,GO:1902495,GO:1990281,GO:1990351 - ko:K03585,ko:K18141 ko01501,ko01503,map01501,map01503 M00646,M00647,M00696,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,8.A.1,8.A.1.6 - iSDY_1059.SDY_0456 Biotin_lipoyl_2,HlyD,HlyD_3,HlyD_D23 k141_5326_1 218284.CCDN010000002_gene2074 4.69e-89 269.0 COG1404@1|root,COG1404@2|Bacteria,1TPZ5@1239|Firmicutes,4HA5F@91061|Bacilli,1ZPUP@1386|Bacillus 91061|Bacilli O Belongs to the peptidase S8 family isp - - ko:K13275 - - - - ko00000,ko01000,ko01002,ko03110 - - - Peptidase_S8 k141_24226_1 218284.CCDN010000005_gene3486 3.07e-85 257.0 COG2188@1|root,COG2188@2|Bacteria,1UYBW@1239|Firmicutes,4HDDG@91061|Bacilli,1ZBS6@1386|Bacillus 91061|Bacilli K transcriptional yvoA - - ko:K03710 - - - - ko00000,ko03000 - - - GntR,UTRA k141_4135_1 1280001.BAOA01000021_gene848 4.74e-128 380.0 COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,1RMVN@1236|Gammaproteobacteria,1XSTB@135623|Vibrionales 135623|Vibrionales M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source glmS GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 - R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 - - - GATase_6,SIS k141_13722_2 218284.CCDN010000001_gene1286 4.96e-125 366.0 COG0133@1|root,COG0133@2|Bacteria,1TPI3@1239|Firmicutes,4H9WC@91061|Bacilli,1ZCBT@1386|Bacillus 91061|Bacilli E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine trpB GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20,5.3.1.24 ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722,R03509 RC00209,RC00210,RC00700,RC00701,RC00945,RC02868 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU22640 PALP k141_11265_1 223926.28809915 3.11e-283 780.0 COG0520@1|root,COG0520@2|Bacteria,1MXH1@1224|Proteobacteria,1RZAJ@1236|Gammaproteobacteria,1XVSS@135623|Vibrionales 135623|Vibrionales E Aminotransferase class-V - - - - - - - - - - - - Aminotran_5 k141_11265_2 1116375.VEJY3_23536 1.65e-262 726.0 COG0642@1|root,COG2205@2|Bacteria,1MXH7@1224|Proteobacteria,1THCY@1236|Gammaproteobacteria,1XU42@135623|Vibrionales 135623|Vibrionales T Signal transduction histidine kinase - - - - - - - - - - - - HisKA k141_11265_3 1116375.VEJY3_23541 2.87e-149 423.0 COG0745@1|root,COG0745@2|Bacteria,1MU3A@1224|Proteobacteria,1RQAV@1236|Gammaproteobacteria,1XURR@135623|Vibrionales 135623|Vibrionales KT COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - - - - - - - - - - Response_reg,Trans_reg_C k141_11265_4 1280001.BAOA01000050_gene1356 2.54e-132 379.0 28TMI@1|root,30GG2@2|Bacteria,1RE0D@1224|Proteobacteria,1S0JA@1236|Gammaproteobacteria,1XUPG@135623|Vibrionales 135623|Vibrionales S Spondin_N - - - - - - - - - - - - Spond_N k141_11265_5 223926.28809921 2.2e-29 110.0 28TMI@1|root,2ZFV4@2|Bacteria,1R9YK@1224|Proteobacteria,1S221@1236|Gammaproteobacteria,1XUFY@135623|Vibrionales 135623|Vibrionales S Spondin_N - - - - - - - - - - - - Spond_N k141_16073_2 1274524.BSONL12_04519 1.82e-42 144.0 COG1191@1|root,COG1191@2|Bacteria,1VNMK@1239|Firmicutes,4HS6F@91061|Bacilli,1ZKM7@1386|Bacillus 91061|Bacilli K Sigma-70, region 4 - - - - - - - - - - - - Sigma70_r4 k141_17258_1 218284.CCDN010000007_gene4021 3.5e-40 140.0 COG4786@1|root,COG4786@2|Bacteria,1TSYY@1239|Firmicutes,4HC6B@91061|Bacilli,1ZCIJ@1386|Bacillus 91061|Bacilli N flagellar basal body flhP GO:0001539,GO:0005575,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009424,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588 - ko:K02392 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C k141_27813_1 218284.CCDN010000001_gene161 1.27e-60 191.0 COG0569@1|root,COG0569@2|Bacteria,1TQ9H@1239|Firmicutes,4HBPH@91061|Bacilli,1ZC2N@1386|Bacillus 91061|Bacilli P COG0569 K transport systems, NAD-binding component ktrA - - ko:K03499 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkA_C,TrkA_N k141_35168_1 218284.CCDN010000005_gene3358 6e-108 316.0 COG1191@1|root,COG1191@2|Bacteria,1V5E6@1239|Firmicutes,4HEBS@91061|Bacilli,1ZCY4@1386|Bacillus 91061|Bacilli K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released sigI - - ko:K03093 - - - - ko00000,ko03021 - - - Sigma70_r2 k141_24408_1 218284.CCDN010000002_gene2046 1.28e-148 422.0 COG0428@1|root,COG0428@2|Bacteria,1TP7J@1239|Firmicutes,4HB3R@91061|Bacilli,1ZB31@1386|Bacillus 91061|Bacilli P Mediates zinc uptake. May also transport other divalent cations XK27_05385 - - ko:K07238 - - - - ko00000,ko02000 2.A.5.5 - - Zip k141_24408_2 218284.CCDN010000002_gene2045 6.77e-19 86.3 28HMX@1|root,2Z7WB@2|Bacteria,1TPJG@1239|Firmicutes,4HBRI@91061|Bacilli,1ZCDH@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_12724_1 218284.CCDN010000001_gene119 9.03e-116 338.0 COG2340@1|root,COG2340@2|Bacteria,1UYZ4@1239|Firmicutes,4HBTC@91061|Bacilli,1ZCGK@1386|Bacillus 91061|Bacilli S protein with SCP PR1 domains ylbC - - - - - - - - - - - CAP,CAP_assoc_N k141_27031_2 1158292.JPOE01000002_gene2704 3.74e-08 57.0 COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,2VH96@28216|Betaproteobacteria 28216|Betaproteobacteria Q copper-resistance protein, CopA family copA - - - - - - - - - - - Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3 k141_11455_1 1219076.N646_2211 2.2e-45 150.0 COG1739@1|root,COG1739@2|Bacteria,1NFJC@1224|Proteobacteria,1RPBF@1236|Gammaproteobacteria,1XTYV@135623|Vibrionales 135623|Vibrionales S Domain of unknown function (DUF1949) yigZ - - - - - - - - - - - DUF1949,UPF0029 k141_11455_2 1116375.VEJY3_00140 0.0 1358.0 COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,1RMZ8@1236|Gammaproteobacteria,1XUGA@135623|Vibrionales 135623|Vibrionales I Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate fadB GO:0003674,GO:0003824,GO:0003857,GO:0004165,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008692,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0016856,GO:0016860,GO:0016863,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 1.1.1.35,4.2.1.17,5.1.2.3,5.3.3.8 ko:K01825 ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212 M00032,M00087 R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R04756,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094 RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01078,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 - - - 3HCDH,3HCDH_N,ECH_1 k141_11455_3 223926.28805011 1.98e-278 761.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RM93@1236|Gammaproteobacteria,1XUI2@135623|Vibrionales 135623|Vibrionales I Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed fadA GO:0003674,GO:0003824,GO:0003988,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0071704,GO:0072329,GO:1901575 2.3.1.16 ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 M00087,M00113 R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095 RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955 ko00000,ko00001,ko00002,ko01000 - - - Thiolase_C,Thiolase_N k141_11455_4 223926.28805010 8e-227 625.0 COG0604@1|root,COG0604@2|Bacteria,1MV3W@1224|Proteobacteria,1RMHG@1236|Gammaproteobacteria,1XUG2@135623|Vibrionales 135623|Vibrionales C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases yhdH - - ko:K19745 ko00640,ko01100,map00640,map01100 - R00919 RC00095 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N k141_11455_5 223926.28805009 6.73e-212 587.0 COG0583@1|root,COG0583@2|Bacteria,1N663@1224|Proteobacteria,1T1CQ@1236|Gammaproteobacteria,1XSHQ@135623|Vibrionales 135623|Vibrionales K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_11455_6 1116375.VEJY3_00120 2.96e-32 112.0 2B57E@1|root,31Y1C@2|Bacteria,1QK8U@1224|Proteobacteria,1TICA@1236|Gammaproteobacteria,1XYUY@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_11455_7 1280001.BAOA01000148_gene2532 1.4e-51 162.0 COG0425@1|root,COG0425@2|Bacteria,1MZA5@1224|Proteobacteria,1S8TC@1236|Gammaproteobacteria,1XYAC@135623|Vibrionales 135623|Vibrionales O Sulfur carrier protein which probably makes part of a sulfur-relay system tusA GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008 - ko:K04085 ko04122,map04122 - - - ko00000,ko00001,ko01000,ko03016 - - - TusA k141_11455_8 1280001.BAOA01000148_gene2533 5.54e-53 166.0 2AWHF@1|root,31NDZ@2|Bacteria,1QK51@1224|Proteobacteria,1TI85@1236|Gammaproteobacteria,1XYM6@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_11455_9 1187848.AJYQ01000119_gene1483 5.57e-115 332.0 COG2119@1|root,COG2119@2|Bacteria,1RDDV@1224|Proteobacteria,1S3QT@1236|Gammaproteobacteria,1XSNJ@135623|Vibrionales 135623|Vibrionales S Uncharacterized protein family UPF0016 - - - - - - - - - - - - UPF0016 k141_11455_10 1205908.AKXW01000128_gene438 8.95e-223 613.0 COG0752@1|root,COG0752@2|Bacteria,1MVCJ@1224|Proteobacteria,1RMYI@1236|Gammaproteobacteria,1XT6R@135623|Vibrionales 135623|Vibrionales J glycyl-trna synthetase alpha subunit glyQ - 6.1.1.14 ko:K01878 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2e k141_11455_11 223926.28805003 0.0 1259.0 COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,1RNR3@1236|Gammaproteobacteria,1XT5T@135623|Vibrionales 135623|Vibrionales J Glycyl-tRNA synthetase beta subunit glyS GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.14 ko:K01879 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_1,tRNA_synt_2f k141_11455_12 1116375.VEJY3_00085 8.8e-302 823.0 COG3977@1|root,COG3977@2|Bacteria,1MVRW@1224|Proteobacteria,1RNK1@1236|Gammaproteobacteria,1XUEC@135623|Vibrionales 135623|Vibrionales E Valine--pyruvate aminotransferase avtA - 2.6.1.66 ko:K00835 ko00290,ko01100,ko01110,ko01130,map00290,map01100,map01110,map01130 - R01215 RC00008,RC00036 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 k141_11455_13 1219076.N646_2196 2.37e-93 273.0 COG0071@1|root,COG0071@2|Bacteria,1RH2X@1224|Proteobacteria,1S6WS@1236|Gammaproteobacteria,1XWXH@135623|Vibrionales 135623|Vibrionales O Belongs to the small heat shock protein (HSP20) family ibpA - - ko:K04080 - - - - ko00000,ko03110 - - - HSP20 k141_11455_15 1280001.BAOA01000148_gene2540 0.0 1521.0 COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,1RNB2@1236|Gammaproteobacteria,1XV37@135623|Vibrionales 135623|Vibrionales L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrB GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009330,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0032991,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.3 ko:K02470 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim k141_11455_16 223926.28804995 7.81e-262 717.0 COG1195@1|root,COG1195@2|Bacteria,1MX8N@1224|Proteobacteria,1RN5P@1236|Gammaproteobacteria,1XTHH@135623|Vibrionales 135623|Vibrionales L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP recF GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - ko:K03629 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - SMC_N k141_11455_17 674977.VMC_08280 8.95e-251 689.0 COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,1RMNP@1236|Gammaproteobacteria,1XSM8@135623|Vibrionales 135623|Vibrionales L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria dnaN GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3 k141_11455_18 1116375.VEJY3_00055 0.0 914.0 COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,1RNHP@1236|Gammaproteobacteria,1XT0F@135623|Vibrionales 135623|Vibrionales L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids dnaA GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006275,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010556,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1901576,GO:1990837,GO:2000112 - ko:K02313 ko02020,ko04112,map02020,map04112 - - - ko00000,ko00001,ko03032,ko03036 - - - Bac_DnaA,Bac_DnaA_C,DnaA_N k141_11455_19 1219076.N646_2188 3.97e-172 481.0 COG0834@1|root,COG0834@2|Bacteria,1MXME@1224|Proteobacteria,1S17B@1236|Gammaproteobacteria,1XUD2@135623|Vibrionales 135623|Vibrionales ET belongs to the bacterial solute-binding protein 3 family patH - - ko:K16961 ko02010,map02010 M00586 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 k141_11455_20 1219076.N646_2187 4.22e-141 400.0 COG0765@1|root,COG0765@2|Bacteria,1QN80@1224|Proteobacteria,1RR3B@1236|Gammaproteobacteria,1XSY9@135623|Vibrionales 135623|Vibrionales P ABC-type amino acid transport system permease component yecS - - ko:K16962 ko02010,map02010 M00586 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 k141_11455_21 223926.28804988 8.65e-170 474.0 COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,1RMX1@1236|Gammaproteobacteria,1XTKQ@135623|Vibrionales 135623|Vibrionales E COG1126 ABC-type polar amino acid transport system, ATPase component tcyC - - ko:K16963 ko02010,map02010 M00586 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran k141_11455_22 55601.VANGNB10_cI0006c 1.72e-20 81.6 COG0230@1|root,COG0230@2|Bacteria,1NGGS@1224|Proteobacteria,1SGDJ@1236|Gammaproteobacteria,1XYVN@135623|Vibrionales 135623|Vibrionales J Belongs to the bacterial ribosomal protein bL34 family rpmH GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02914 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L34 k141_11455_23 223926.28804986 1.47e-69 210.0 COG0594@1|root,COG0594@2|Bacteria,1MZQE@1224|Proteobacteria,1S90M@1236|Gammaproteobacteria,1XXEW@135623|Vibrionales 135623|Vibrionales J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme rnpA GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031974,GO:0031981,GO:0032991,GO:0034641,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 ko:K03536 - - - - ko00000,ko01000,ko03016 - - - Ribonuclease_P k141_11455_24 1116375.VEJY3_00020 0.0 1054.0 COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,1RMH1@1236|Gammaproteobacteria,1XU5N@135623|Vibrionales 135623|Vibrionales U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins yidC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 - - 60KD_IMP,YidC_periplas k141_11455_25 223926.28804984 2.48e-308 842.0 COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,1RN5S@1236|Gammaproteobacteria,1XTKD@135623|Vibrionales 135623|Vibrionales J Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 mnmE GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009636,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050896,GO:0071704,GO:0090304,GO:1901360 - ko:K03650 - - R08701 RC00053,RC00209,RC00870 ko00000,ko01000,ko03016 - - - MMR_HSR1,MnmE_helical,TrmE_N k141_36187_1 218284.CCDN010000005_gene3467 5.89e-39 134.0 28K3D@1|root,2Z9SI@2|Bacteria,1UZKH@1239|Firmicutes,4HDH6@91061|Bacilli,1ZI4E@1386|Bacillus 91061|Bacilli S MEDS: MEthanogen/methylotroph, DcmR Sensory domain - - - - - - - - - - - - MEDS k141_18594_1 1294265.JCM21738_4574 4.33e-107 322.0 COG2812@1|root,COG2812@2|Bacteria,1TPS9@1239|Firmicutes,4HAUE@91061|Bacilli,1ZB2M@1386|Bacillus 91061|Bacilli L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity dnaX GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNA_pol3_gamma3 k141_37373_1 1089552.KI911559_gene1690 4.39e-39 143.0 COG0457@1|root,COG0457@2|Bacteria,1N01S@1224|Proteobacteria,2TSR4@28211|Alphaproteobacteria,2JQKI@204441|Rhodospirillales 204441|Rhodospirillales S COG0457 FOG TPR repeat - - - - - - - - - - - - - k141_37373_2 396588.Tgr7_3075 1.47e-34 126.0 COG3431@1|root,COG3431@2|Bacteria,1N6PE@1224|Proteobacteria,1S9EB@1236|Gammaproteobacteria,1X2R5@135613|Chromatiales 135613|Chromatiales S Sensors of blue-light using FAD - - - - - - - - - - - - BLUF k141_37373_3 1453501.JELR01000001_gene2006 2.38e-97 291.0 COG1075@1|root,COG1075@2|Bacteria,1N2W0@1224|Proteobacteria,1S2JW@1236|Gammaproteobacteria,46749@72275|Alteromonadaceae 1236|Gammaproteobacteria S acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - - - - - - - - - - Abhydrolase_6,DUF676,Hydrolase_4 k141_37373_4 1453501.JELR01000001_gene2004 5.45e-143 413.0 COG0668@1|root,COG0668@2|Bacteria,1N596@1224|Proteobacteria,1RQZP@1236|Gammaproteobacteria,465C6@72275|Alteromonadaceae 1236|Gammaproteobacteria M Mechanosensitive ion channel - - - - - - - - - - - - MS_channel k141_37373_5 1279017.AQYJ01000029_gene3394 1.34e-64 201.0 COG2153@1|root,COG2153@2|Bacteria,1MZHA@1224|Proteobacteria,1S9IF@1236|Gammaproteobacteria,467VR@72275|Alteromonadaceae 1236|Gammaproteobacteria S Acetyltransferase (GNAT) domain elaA - - ko:K02348 - - - - ko00000 - - - Acetyltransf_10 k141_37373_6 765910.MARPU_09405 6.96e-43 143.0 COG2076@1|root,COG2076@2|Bacteria,1MZ54@1224|Proteobacteria,1S8SG@1236|Gammaproteobacteria,1WYUP@135613|Chromatiales 135613|Chromatiales U PFAM small multidrug resistance protein - - - ko:K03297 - - - - ko00000,ko02000 2.A.7.1 - - Multi_Drug_Res k141_37373_7 1279017.AQYJ01000029_gene3390 4.05e-312 858.0 COG2978@1|root,COG2978@2|Bacteria,1MUJ1@1224|Proteobacteria,1RMAI@1236|Gammaproteobacteria,4642F@72275|Alteromonadaceae 1236|Gammaproteobacteria H Transporter abgT - - ko:K12942 - - - - ko00000 - - - ABG_transport k141_37373_12 1279017.AQYJ01000026_gene265 2.23e-156 451.0 COG0438@1|root,COG0438@2|Bacteria,1NA28@1224|Proteobacteria,1RQBV@1236|Gammaproteobacteria,4668K@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0438 Glycosyltransferase - - - - - - - - - - - - DUF3524,Glyco_trans_1_4,Glycos_transf_1 k141_37373_14 1279017.AQYJ01000026_gene267 8.82e-157 443.0 COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,1RQQT@1236|Gammaproteobacteria,465TH@72275|Alteromonadaceae 1236|Gammaproteobacteria V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin uppP - 3.6.1.27 ko:K06153 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - BacA k141_37373_15 1279017.AQYJ01000026_gene268 2.84e-102 303.0 COG1214@1|root,COG1214@2|Bacteria,1MXPH@1224|Proteobacteria,1RPYX@1236|Gammaproteobacteria,466QS@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG1214 Inactive homolog of metal-dependent proteases yeaZ GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 - ko:K14742 - - - - ko00000,ko03016 - - - Peptidase_M22 k141_37373_17 1042377.AFPJ01000037_gene2845 1.06e-170 484.0 COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,1RMMS@1236|Gammaproteobacteria,4643H@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the ferrous insertion into protoporphyrin IX hemH GO:0003674,GO:0003824,GO:0004325,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009314,GO:0009416,GO:0009628,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0050896,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R00310,R11329 RC01012 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_1540,iECS88_1305.ECS88_0472,iEcE24377_1341.EcE24377A_0515 Ferrochelatase k141_37373_19 402777.KB235904_gene3941 3.37e-129 379.0 COG1052@1|root,COG1052@2|Bacteria,1G028@1117|Cyanobacteria,1H7XD@1150|Oscillatoriales 1117|Cyanobacteria CH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ddh - 1.1.1.28 ko:K03778 ko00620,ko01120,map00620,map01120 - R00704 RC00044 ko00000,ko00001,ko01000 - - - 2-Hacid_dh,2-Hacid_dh_C k141_37373_20 1279017.AQYJ01000026_gene272 1.23e-148 423.0 COG1694@1|root,COG3956@2|Bacteria,1MVKM@1224|Proteobacteria,1RNVU@1236|Gammaproteobacteria,465UD@72275|Alteromonadaceae 1236|Gammaproteobacteria S Pyrophosphatase mazG GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009267,GO:0009394,GO:0009605,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042594,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.9 ko:K04765 ko00230,ko00240,ko00760,ko00770,ko01100,map00230,map00240,map00760,map00770,map01100 - R00086,R00087,R00103,R00287,R00426,R00515,R00662,R00720,R03004,R03036,R11323 RC00002 ko00000,ko00001,ko01000 - - iAF1260.b2781,iBWG_1329.BWG_2516,iE2348C_1286.E2348C_3048,iEC55989_1330.EC55989_3056,iECDH10B_1368.ECDH10B_2948,iECDH1ME8569_1439.ECDH1ME8569_2691,iECH74115_1262.ECH74115_4041,iECIAI1_1343.ECIAI1_2889,iECO103_1326.ECO103_3324,iECO111_1330.ECO111_3505,iECO26_1355.ECO26_3851,iECOK1_1307.ECOK1_3155,iECP_1309.ECP_2762,iECSE_1348.ECSE_3039,iECSP_1301.ECSP_3733,iECW_1372.ECW_m2990,iECs_1301.ECs3641,iEKO11_1354.EKO11_0987,iEcDH1_1363.EcDH1_0907,iEcE24377_1341.EcE24377A_3085,iEcHS_1320.EcHS_A2925,iEcolC_1368.EcolC_0931,iG2583_1286.G2583_3433,iJO1366.b2781,iJR904.b2781,iSBO_1134.SBO_2662,iSSON_1240.SSON_2938,iSbBS512_1146.SbBS512_E3092,iUMN146_1321.UM146_02665,iUMNK88_1353.UMNK88_3464,iUTI89_1310.UTI89_C3150,iWFL_1372.ECW_m2990,iY75_1357.Y75_RS14470,iZ_1308.Z4096 MazG k141_37373_21 1279017.AQYJ01000026_gene273 0.0 1325.0 COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,1RN3H@1236|Gammaproteobacteria,4654N@72275|Alteromonadaceae 1236|Gammaproteobacteria KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance relA GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015949,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5 ko:K00951 ko00230,map00230 - R00429 RC00002,RC00078 ko00000,ko00001,ko01000 - - iSFV_1184.SFV_2673 ACT_4,HD_4,RelA_SpoT,TGS k141_37373_22 1279017.AQYJ01000026_gene274 1.24e-183 514.0 COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,1RN6J@1236|Gammaproteobacteria,464QD@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the cysteine synthase cystathionine beta- synthase family cysM GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 ko:K12339 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03132,R03601,R04859 RC00020,RC02814,RC02821,RC02876 ko00000,ko00001,ko00002,ko01000 - - iECP_1309.ECP_2444 PALP k141_37373_23 1279017.AQYJ01000026_gene275 0.0 1219.0 COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,464QT@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0642 Signal transduction histidine kinase barA GO:0000155,GO:0000160,GO:0000302,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009636,GO:0009927,GO:0009987,GO:0010033,GO:0010035,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0035556,GO:0036211,GO:0042221,GO:0042493,GO:0042542,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046677,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0070887,GO:0071310,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901700 2.7.13.3 ko:K07678 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 M00475 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - DUF2222,HAMP,HATPase_c,HisKA,Hpt,Response_reg k141_37373_24 1279017.AQYJ01000026_gene276 4.62e-54 172.0 COG0736@1|root,COG0736@2|Bacteria,1MZBF@1224|Proteobacteria,1S98P@1236|Gammaproteobacteria,467XX@72275|Alteromonadaceae 1236|Gammaproteobacteria I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein acpS GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008897,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016780,GO:0018070,GO:0018193,GO:0018209,GO:0018215,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901576 2.7.8.7 ko:K00997 ko00770,map00770 - R01625 RC00002 ko00000,ko00001,ko01000 - - - ACPS k141_37373_25 1453501.JELR01000001_gene1991 3.27e-99 296.0 COG1381@1|root,COG1381@2|Bacteria,1RHIC@1224|Proteobacteria,1RN8Y@1236|Gammaproteobacteria,46776@72275|Alteromonadaceae 1236|Gammaproteobacteria L Involved in DNA repair and RecF pathway recombination recO GO:0008150,GO:0009314,GO:0009628,GO:0050896 - ko:K03584 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecO_C,RecO_N k141_37373_26 1279017.AQYJ01000026_gene278 8.41e-194 541.0 COG1159@1|root,COG1159@2|Bacteria,1MUKT@1224|Proteobacteria,1RN3A@1236|Gammaproteobacteria,464IK@72275|Alteromonadaceae 1236|Gammaproteobacteria S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism era GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009898,GO:0009987,GO:0016020,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019538,GO:0019843,GO:0019897,GO:0019898,GO:0022613,GO:0031234,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0036211,GO:0042254,GO:0042274,GO:0043021,GO:0043024,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044877,GO:0046777,GO:0070181,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363,GO:1901564 - ko:K03595 - - - - ko00000,ko03009,ko03029 - - - KH_2,MMR_HSR1 k141_37373_27 1279017.AQYJ01000026_gene279 1.17e-128 369.0 COG0571@1|root,COG0571@2|Bacteria,1MUQ6@1224|Proteobacteria,1RN0C@1236|Gammaproteobacteria,466PY@72275|Alteromonadaceae 1236|Gammaproteobacteria J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism rnc GO:0000287,GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019899,GO:0022613,GO:0032296,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 ko:K03685 ko03008,ko05205,map03008,map05205 - - - ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 - - - Ribonucleas_3_3,dsrm k141_37373_28 1279017.AQYJ01000026_gene280 1.37e-72 221.0 COG4969@1|root,COG4969@2|Bacteria,1N71K@1224|Proteobacteria,1SCYD@1236|Gammaproteobacteria,468QS@72275|Alteromonadaceae 1236|Gammaproteobacteria NU Domain of unknown function (DUF4845) - - - - - - - - - - - - DUF4845 k141_37373_29 1279017.AQYJ01000026_gene281 4.37e-151 428.0 COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,1RMHI@1236|Gammaproteobacteria,464B8@72275|Alteromonadaceae 1236|Gammaproteobacteria U Belongs to the peptidase S26 family lepB GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24,Peptidase_S26 k141_37373_30 1279017.AQYJ01000026_gene282 0.0 1113.0 COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,1RPFB@1236|Gammaproteobacteria,465YM@72275|Alteromonadaceae 1236|Gammaproteobacteria M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner lepA GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0006950,GO:0006970,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009268,GO:0009409,GO:0009628,GO:0009651,GO:0009987,GO:0010467,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019538,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0042802,GO:0043021,GO:0043023,GO:0043024,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0050896,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K03596 ko05134,map05134 - - - ko00000,ko00001 - - - EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C k141_37373_31 1279017.AQYJ01000026_gene283 1.2e-261 725.0 COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,464ES@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the peptidase S1C family mucD GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Trypsin_2 k141_37373_32 561229.Dd1591_1769 1.89e-105 311.0 COG2866@1|root,COG2866@2|Bacteria,1N9AY@1224|Proteobacteria,1RRGU@1236|Gammaproteobacteria,2JD8B@204037|Dickeya 1236|Gammaproteobacteria E PFAM peptidase M14 carboxypeptidase A mpaA GO:0000270,GO:0003674,GO:0003824,GO:0004040,GO:0004180,GO:0004181,GO:0005488,GO:0006022,GO:0006026,GO:0006027,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0009050,GO:0009056,GO:0009057,GO:0009253,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0019538,GO:0030203,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0046872,GO:0046914,GO:0061473,GO:0070011,GO:0071704,GO:0140096,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - ko:K14054 - - - - ko00000 - - iEC55989_1330.EC55989_1490,iECO103_1326.ECO103_1491 Peptidase_M14 k141_37373_33 1279017.AQYJ01000026_gene285 4.19e-159 453.0 COG4948@1|root,COG4948@2|Bacteria,1MW76@1224|Proteobacteria,1RMKS@1236|Gammaproteobacteria,466KF@72275|Alteromonadaceae 1236|Gammaproteobacteria M Mandelate racemase / muconate lactonizing enzyme, C-terminal domain ycjG GO:0003674,GO:0003824,GO:0016853,GO:0016854,GO:0016855 5.1.1.20,5.5.1.1 ko:K01856,ko:K19802 ko00361,ko00362,ko00364,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00364,map00623,map01100,map01120,map01220 M00568 R05300,R05390,R06989,R08116,R09229,R10938 RC00903,RC01038,RC01108,RC01321,RC01356,RC03309 ko00000,ko00001,ko00002,ko01000 - - iEC042_1314.EC042_1441,iECUMN_1333.ECUMN_1620 MR_MLE_C,MR_MLE_N k141_37373_34 1042377.AFPJ01000037_gene2860 3.74e-49 162.0 COG3086@1|root,COG3086@2|Bacteria,1N6QS@1224|Proteobacteria,1SCTM@1236|Gammaproteobacteria,468GR@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG3086 Positive regulator of sigma E activity rseC GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0016020,GO:0044464,GO:0050896,GO:0071944 - ko:K03803 - - - - ko00000,ko03021 - - - RseC_MucC k141_37373_35 1279017.AQYJ01000026_gene287 1.95e-133 393.0 COG3026@1|root,COG3026@2|Bacteria,1MUQ8@1224|Proteobacteria,1RNF3@1236|Gammaproteobacteria,467RQ@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG3026 Negative regulator of sigma E activity rseB GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0044464,GO:0045152 - ko:K03598 - - - - ko00000,ko03021 - - - MucB_RseB,MucB_RseB_C k141_37373_36 1279017.AQYJ01000026_gene288 7.71e-80 246.0 COG3073@1|root,COG3073@2|Bacteria,1N9FN@1224|Proteobacteria,1SCNH@1236|Gammaproteobacteria,46CT4@72275|Alteromonadaceae 1236|Gammaproteobacteria T Anti sigma-E protein RseA, N-terminal domain algS - - ko:K03597 - - - - ko00000,ko03021 - - - RseA_C,RseA_N k141_10337_1 1219076.N646_2040 2.01e-120 355.0 COG0534@1|root,COG0534@2|Bacteria,1MV6B@1224|Proteobacteria,1RPGF@1236|Gammaproteobacteria,1XSWY@135623|Vibrionales 135623|Vibrionales V Na driven multidrug efflux pump dinF - - ko:K03327 - - - - ko00000,ko02000 2.A.66.1 - - MatE k141_22033_1 1347369.CCAD010000007_gene2352 4.01e-14 70.9 COG0172@1|root,COG0172@2|Bacteria,1TP4W@1239|Firmicutes,4H9Y4@91061|Bacilli,1ZCBQ@1386|Bacillus 91061|Bacilli J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) serS - 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Seryl_tRNA_N,tRNA-synt_2b k141_22033_2 1294265.JCM21738_4564 1.77e-36 127.0 COG0311@1|root,COG0311@2|Bacteria,1V3I6@1239|Firmicutes,4HFSZ@91061|Bacilli,1ZD5C@1386|Bacillus 91061|Bacilli H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS pdxT GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 ko:K08681 ko00750,map00750 - R07456 RC00010,RC01783,RC03043 ko00000,ko00001,ko01000 - - - SNO k141_796_1 225937.HP15_2637 1.12e-49 174.0 COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,1RPNE@1236|Gammaproteobacteria,464ZH@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1022 Long-chain acyl-CoA synthetases (AMP-forming) fadD - - - - - - - - - - - AMP-binding k141_20780_1 674977.VMC_00620 4.1e-166 471.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RMMJ@1236|Gammaproteobacteria,1Y0CS@135623|Vibrionales 135623|Vibrionales C Acyl-CoA dehydrogenase, C-terminal domain - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_20780_2 674977.VMC_00610 1.65e-169 475.0 COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,1RR3Z@1236|Gammaproteobacteria,1Y2K6@135623|Vibrionales 135623|Vibrionales I Enoyl-CoA hydratase/isomerase - - - - - - - - - - - - ECH_1 k141_20780_3 674977.VMC_00600 9.43e-59 188.0 COG1024@1|root,COG1024@2|Bacteria,1MU0B@1224|Proteobacteria 1224|Proteobacteria I Enoyl-CoA hydratase - - - - - - - - - - - - ECH_2 k141_6639_1 42565.FP66_06245 4.72e-64 206.0 COG1686@1|root,COG1686@2|Bacteria,1MUU7@1224|Proteobacteria,1RMJA@1236|Gammaproteobacteria,1XI5M@135619|Oceanospirillales 135619|Oceanospirillales M Belongs to the peptidase S11 family dacA - 3.4.16.4 ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - PBP5_C,Peptidase_S11 k141_12742_1 666686.B1NLA3E_03215 1.46e-67 213.0 2A8A0@1|root,30XBB@2|Bacteria,1V5X0@1239|Firmicutes,4HHA9@91061|Bacilli,1ZCED@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF3784) - - - - - - - - - - - - DUF3784,bPH_5 k141_18619_1 1294265.JCM21738_3520 3.22e-62 195.0 COG1646@1|root,COG1646@2|Bacteria,1TQQK@1239|Firmicutes,4H9YW@91061|Bacilli,1ZBBT@1386|Bacillus 91061|Bacilli I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales pcrB GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 - ko:K07094 - - - - ko00000,ko01000 - - - PcrB k141_18619_2 994573.T472_0218580 1.79e-19 90.1 COG0591@1|root,COG0591@2|Bacteria,1TPVE@1239|Firmicutes,248NQ@186801|Clostridia,36FNJ@31979|Clostridiaceae 186801|Clostridia E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - ko:K03307 - - - - ko00000 2.A.21 - - SSF k141_32628_1 42565.FP66_00735 5.27e-149 431.0 COG0397@1|root,COG0397@2|Bacteria,1MVK3@1224|Proteobacteria,1RNCS@1236|Gammaproteobacteria,1XH4M@135619|Oceanospirillales 135619|Oceanospirillales S Belongs to the UPF0061 (SELO) family - - - - - - - - - - - - UPF0061 k141_30222_3 35841.BT1A1_0106 1.62e-89 263.0 COG0080@1|root,COG0080@2|Bacteria,1V1BS@1239|Firmicutes,4HFQ0@91061|Bacilli,1ZFIG@1386|Bacillus 91061|Bacilli J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors rplK GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02867 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L11,Ribosomal_L11_N k141_797_2 218284.CCDN010000002_gene1988 2.23e-95 298.0 COG0046@1|root,COG0046@2|Bacteria,1TPAS@1239|Firmicutes,4HB3N@91061|Bacilli,1ZCN8@1386|Bacillus 91061|Bacilli F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL purL GO:0003674,GO:0003824,GO:0004642,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C k141_33977_1 1307436.PBF_17914 4.13e-165 468.0 COG1404@1|root,COG1404@2|Bacteria,1TS1X@1239|Firmicutes,4HCN0@91061|Bacilli,1ZDZ4@1386|Bacillus 91061|Bacilli O COG1404 Subtilisin-like serine proteases - - - ko:K20486 ko02020,ko02024,map02020,map02024 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S8 k141_6640_1 913325.N799_13565 2.59e-79 255.0 COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RMFF@1236|Gammaproteobacteria,1X3MV@135614|Xanthomonadales 135614|Xanthomonadales C dehydrogenase lpdA - 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim k141_24445_1 218284.CCDN010000001_gene983 2.6e-103 308.0 COG3426@1|root,COG3426@2|Bacteria,1TPKE@1239|Firmicutes,4H9QV@91061|Bacilli,1ZC7E@1386|Bacillus 91061|Bacilli C Belongs to the acetokinase family buk - 2.7.2.7 ko:K00929 ko00650,ko01100,map00650,map01100 - R01688 RC00002,RC00043 ko00000,ko00001,ko01000 - - - Acetate_kinase k141_5538_1 1169144.KB910992_gene2873 9.4e-99 295.0 COG0533@1|root,COG0533@2|Bacteria,1TQDR@1239|Firmicutes,4HANB@91061|Bacilli,1ZBT3@1386|Bacillus 91061|Bacilli O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction tsaD GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 ko:K01409 - - R10648 RC00070,RC00416 ko00000,ko01000,ko03016 - - - Peptidase_M22 k141_27063_1 290397.Adeh_0927 9.89e-38 131.0 COG0432@1|root,COG0432@2|Bacteria,1RH13@1224|Proteobacteria,42TJK@68525|delta/epsilon subdivisions,2WQ0Z@28221|Deltaproteobacteria 28221|Deltaproteobacteria S PFAM Uncharacterised protein family UPF0047 - - - - - - - - - - - - UPF0047 k141_6641_1 1453501.JELR01000002_gene154 8.57e-84 251.0 COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,1S41D@1236|Gammaproteobacteria,467B9@72275|Alteromonadaceae 1236|Gammaproteobacteria D COG0424 Nucleotide-binding protein implicated in inhibition of septum formation yhdE GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030145,GO:0036218,GO:0036221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0047429 - ko:K06287 - - - - ko00000 - - - Maf k141_12743_1 218284.CCDN010000002_gene2648 4.24e-76 229.0 COG0537@1|root,COG0537@2|Bacteria,1VB6J@1239|Firmicutes,4HIE1@91061|Bacilli,1ZFUM@1386|Bacillus 91061|Bacilli FG HIT domain - - - ko:K02503 - - - - ko00000,ko04147 - - - HIT k141_7699_1 87626.PTD2_19642 1.13e-23 100.0 COG0705@1|root,COG0705@2|Bacteria,1N8NS@1224|Proteobacteria,1SD4M@1236|Gammaproteobacteria,2Q1K9@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria S membrane protein (homolog of Drosophila rhomboid) - - - - - - - - - - - - Rhomboid k141_7699_2 1279017.AQYJ01000024_gene1154 4.28e-150 429.0 COG0656@1|root,COG0656@2|Bacteria,1MWFS@1224|Proteobacteria,1RMX6@1236|Gammaproteobacteria,467B4@72275|Alteromonadaceae 1236|Gammaproteobacteria S Aldo/keto reductase family dkgA GO:0003674,GO:0003824,GO:0004033,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0008106,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0042180,GO:0042182,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0051596,GO:0055114,GO:0071704,GO:1901575 1.1.1.307,1.1.1.346 ko:K06221,ko:K17743 ko00040,ko01100,map00040,map01100 - R01431,R08878,R09477 RC00089,RC00133 ko00000,ko00001,ko01000 - - iECH74115_1262.ECH74115_4323,iECSP_1301.ECSP_3988 Aldo_ket_red k141_7699_5 1453501.JELR01000001_gene2875 1.92e-65 199.0 COG3070@1|root,COG3070@2|Bacteria,1NAYG@1224|Proteobacteria,1SDXZ@1236|Gammaproteobacteria,46BQS@72275|Alteromonadaceae 1236|Gammaproteobacteria K TfoX N-terminal domain - - - - - - - - - - - - TfoX_N k141_7699_6 1453501.JELR01000001_gene2876 1.35e-39 135.0 COG5646@1|root,COG5646@2|Bacteria,1N8IH@1224|Proteobacteria,1SDPM@1236|Gammaproteobacteria,46BSX@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DU1801) - - - - - - - - - - - - DUF1801 k141_7699_7 1205683.CAKR01000009_gene1442 4.17e-103 306.0 COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,1S237@1236|Gammaproteobacteria,41ESJ@629|Yersinia 1236|Gammaproteobacteria P Reversible hydration of carbon dioxide cynT - 4.2.1.1 ko:K01673 ko00910,map00910 - R00132,R10092 RC02807 ko00000,ko00001,ko01000 - - - Pro_CA k141_7699_8 1453501.JELR01000001_gene2877 0.0 2277.0 COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,1RMRN@1236|Gammaproteobacteria,464EF@72275|Alteromonadaceae 1236|Gammaproteobacteria F Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate purL GO:0000166,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006520,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016874,GO:0016879,GO:0016884,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - iECH74115_1262.ECH74115_3792,iECO111_1330.ECO111_3283,iECSP_1301.ECSP_3501,iECs_1301.ECs3423,iG2583_1286.G2583_3088,iJN746.PP_1037,ic_1306.c3080 AIRS_C,GATase_5 k141_7699_9 1279017.AQYJ01000024_gene1151 5.8e-281 776.0 COG4623@1|root,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,1RM8W@1236|Gammaproteobacteria,4640D@72275|Alteromonadaceae 1236|Gammaproteobacteria M Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella mltF GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009279,GO:0016020,GO:0016740,GO:0016757,GO:0019867,GO:0030203,GO:0030312,GO:0030313,GO:0031975,GO:0043170,GO:0044462,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - ko:K18691 - - - - ko00000,ko01000,ko01011 - - iBWG_1329.BWG_2322,iEC042_1314.EC042_2762,iECDH1ME8569_1439.ECDH1ME8569_2485,iECNA114_1301.ECNA114_2631,iECP_1309.ECP_2560,iECSF_1327.ECSF_2397,iECW_1372.ECW_m2786,iEKO11_1354.EKO11_1175,iEcDH1_1363.EcDH1_1110,iEcHS_1320.EcHS_A2711,iEcolC_1368.EcolC_1119,iG2583_1286.G2583_3089,iJO1366.b2558,iSFxv_1172.SFxv_2861,iUMN146_1321.UM146_03930,iUMNK88_1353.UMNK88_3212,iUTI89_1310.UTI89_C2878,iWFL_1372.ECW_m2786,iY75_1357.Y75_RS13345 SBP_bac_3,SLT k141_6865_1 1116375.VEJY3_13020 3.99e-107 314.0 COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,1RMBU@1236|Gammaproteobacteria,1XTQ3@135623|Vibrionales 135623|Vibrionales H Belongs to the NadC ModD family nadC - 2.4.2.19 ko:K00767 ko00760,ko01100,map00760,map01100 M00115 R03348 RC02877 ko00000,ko00001,ko00002,ko01000 - - - QRPTase_C,QRPTase_N k141_6865_2 1116375.VEJY3_13015 3.01e-118 339.0 COG3023@1|root,COG3023@2|Bacteria,1RDHU@1224|Proteobacteria,1S3PG@1236|Gammaproteobacteria,1XTXJ@135623|Vibrionales 135623|Vibrionales V COG3023 Negative regulator of beta-lactamase expression ampD - 3.5.1.28 ko:K03806 - - - - ko00000,ko01000,ko01011 - - - Amidase_2 k141_6865_3 1116375.VEJY3_13010 1.35e-162 457.0 COG2186@1|root,COG2186@2|Bacteria,1MUP9@1224|Proteobacteria,1RNPJ@1236|Gammaproteobacteria,1XV1H@135623|Vibrionales 135623|Vibrionales K COG2186 Transcriptional regulators pdhR - - ko:K05799 - - - - ko00000,ko03000 - - - FCD,GntR k141_6865_4 223926.28807517 0.0 1763.0 COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,1RN6K@1236|Gammaproteobacteria,1XU1V@135623|Vibrionales 135623|Vibrionales C Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) aceE - 1.2.4.1 ko:K00163 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - Transketolase_N k141_6865_5 1116375.VEJY3_13000 1.58e-43 156.0 COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,1RNPT@1236|Gammaproteobacteria,1XT8J@135623|Vibrionales 135623|Vibrionales C The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) aceF - 2.3.1.12 ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding k141_9308_1 218284.CCDN010000002_gene2109 1.74e-68 220.0 COG1249@1|root,COG1249@2|Bacteria,1UYJP@1239|Firmicutes,4HCWF@91061|Bacilli,1ZED9@1386|Bacillus 91061|Bacilli C Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain - - 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyr_redox_2,Pyr_redox_dim k141_9308_2 218284.CCDN010000002_gene2110 1.16e-224 622.0 COG3185@1|root,COG3185@2|Bacteria,1UZP2@1239|Firmicutes,4HDQI@91061|Bacilli,1ZEQ2@1386|Bacillus 91061|Bacilli E 4-hydroxyphenylpyruvate dioxygenase hppD - 1.13.11.27 ko:K00457 ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100 M00044 R01372,R02521 RC00505,RC00738 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Glyoxalase,Glyoxalase_5 k141_11669_1 1191523.MROS_1723 2.38e-83 268.0 COG1185@1|root,COG1185@2|Bacteria 2|Bacteria J polyribonucleotide nucleotidyltransferase activity pnp GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 M00394 R00437,R00438,R00439,R00440 RC02795 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 - - - KH_1,PNPase,RNase_PH,RNase_PH_C,S1 k141_18891_1 796606.BMMGA3_15050 5.14e-49 162.0 COG1739@1|root,COG1739@2|Bacteria,1V6MQ@1239|Firmicutes,4HBIT@91061|Bacilli,1ZAXD@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF1949) yvyE - 3.4.13.9 ko:K01271 - - - - ko00000,ko01000,ko01002 - - - DUF1949,UPF0029 k141_27308_1 218284.CCDN010000001_gene1493 4.39e-48 159.0 COG1174@1|root,COG1174@2|Bacteria,1UHWH@1239|Firmicutes,4ISE5@91061|Bacilli,1ZS6F@1386|Bacillus 91061|Bacilli E Binding-protein-dependent transport system inner membrane component - - - ko:K05846 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - BPD_transp_1 k141_27308_2 218284.CCDN010000001_gene1492 9.72e-130 374.0 COG1732@1|root,COG1732@2|Bacteria,1TQ7D@1239|Firmicutes,4HARV@91061|Bacilli,1ZQFN@1386|Bacillus 91061|Bacilli M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) opuCC GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0016020,GO:0031460,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0072337 - ko:K05845 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - OpuAC k141_36323_1 1174504.AJTN02000174_gene3950 8.31e-24 98.2 COG0134@1|root,COG0134@2|Bacteria,1TR94@1239|Firmicutes,4HDZQ@91061|Bacilli,1ZD63@1386|Bacillus 91061|Bacilli E Belongs to the TrpC family trpC GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48,5.3.1.24 ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03508,R03509 RC00944,RC00945 ko00000,ko00001,ko00002,ko01000 - - - IGPS k141_36323_2 1348908.KI518615_gene1204 7.13e-16 77.8 COG0547@1|root,COG0547@2|Bacteria,1TP8U@1239|Firmicutes,4H9KQ@91061|Bacilli,1ZBZ1@1386|Bacillus 91061|Bacilli E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) trpD GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0004425,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R00985,R00986,R01073 RC00010,RC00440,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Glycos_trans_3N,Glycos_transf_3 k141_37530_2 1294265.JCM21738_3651 1.42e-66 213.0 COG2208@1|root,COG2208@2|Bacteria,1TQ92@1239|Firmicutes,4HB0X@91061|Bacilli,1ZAYZ@1386|Bacillus 91061|Bacilli KT stage II sporulation protein E spoIIE GO:0005575,GO:0005623,GO:0042601,GO:0042763,GO:0044464 3.1.3.16 ko:K06382 - - - - ko00000,ko01000 - - - SpoIIE k141_34136_1 204669.Acid345_2647 1.34e-13 72.4 COG1975@1|root,COG1975@2|Bacteria,3Y54Y@57723|Acidobacteria,2JP44@204432|Acidobacteriia 204432|Acidobacteriia C XdhC and CoxI family - - - ko:K07402 - - - - ko00000 - - - XdhC_C,XdhC_CoxI k141_6866_1 935836.JAEL01000005_gene2648 6.12e-44 152.0 COG3342@1|root,COG3342@2|Bacteria,1TS8U@1239|Firmicutes,4HBYK@91061|Bacilli,1ZCG3@1386|Bacillus 91061|Bacilli S Family of unknown function (DUF1028) - - - - - - - - - - - - DUF1028,PG_binding_2 k141_22286_1 1042377.AFPJ01000024_gene779 1.24e-22 95.5 COG3660@1|root,COG3660@2|Bacteria,1RC47@1224|Proteobacteria,1S53F@1236|Gammaproteobacteria,469PG@72275|Alteromonadaceae 1236|Gammaproteobacteria M Mitochondrial fission ELM1 - - - ko:K07276 - - - - ko00000 - - - Mito_fiss_Elm1 k141_22286_2 1410620.SHLA_26c000720 6.97e-90 292.0 COG0438@1|root,COG0438@2|Bacteria,1MUTA@1224|Proteobacteria,2TSPN@28211|Alphaproteobacteria,4BH5H@82115|Rhizobiaceae 28211|Alphaproteobacteria M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1 k141_22286_3 1042377.AFPJ01000052_gene1541 1.71e-144 419.0 COG0836@1|root,COG0836@2|Bacteria,1MV39@1224|Proteobacteria,1RNQI@1236|Gammaproteobacteria,4644C@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the mannose-6-phosphate isomerase type 2 family cpsB GO:0000271,GO:0003674,GO:0003824,GO:0004475,GO:0005975,GO:0005976,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0008152,GO:0008905,GO:0008928,GO:0009058,GO:0009059,GO:0009242,GO:0009628,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016772,GO:0016779,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046377,GO:0050896,GO:0070568,GO:0071704,GO:1901135,GO:1901137,GO:1901576 2.7.7.13,5.3.1.8 ko:K00971,ko:K16011 ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025 M00114,M00361,M00362 R00885,R01819 RC00002,RC00376 ko00000,ko00001,ko00002,ko01000 - - iE2348C_1286.E2348C_2191,iEC042_1314.EC042_2286,iECIAI1_1343.ECIAI1_2124,iECO26_1355.ECO26_2960,iECSE_1348.ECSE_2323,iECW_1372.ECW_m2206,iEKO11_1354.EKO11_1746,iEcE24377_1341.EcE24377A_2342,iLF82_1304.LF82_0345,iNRG857_1313.NRG857_10420,iWFL_1372.ECW_m2206 MannoseP_isomer,NTP_transferase k141_29308_1 391615.ABSJ01000042_gene2284 5.17e-44 162.0 COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,1RM7J@1236|Gammaproteobacteria,1J4BX@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M penicillin-binding protein mrcA GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0008955,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - PCB_OB,Transgly,Transpeptidase k141_18892_1 218284.CCDN010000001_gene94 1.21e-103 313.0 COG4365@1|root,COG4365@2|Bacteria,1TQ2P@1239|Firmicutes,4HA2Z@91061|Bacilli,1ZBMV@1386|Bacillus 91061|Bacilli S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH bshC - - ko:K22136 - - - - ko00000 - - - BshC k141_16261_1 1453501.JELR01000002_gene1048 5.6e-28 110.0 COG0454@1|root,COG0456@2|Bacteria,1MVZ2@1224|Proteobacteria,1RSC5@1236|Gammaproteobacteria,465P6@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG0456 Acetyltransferases - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10,DUF3335 k141_3139_1 42565.FP66_03090 2.52e-37 134.0 COG0006@1|root,COG0006@2|Bacteria,1MWUT@1224|Proteobacteria,1RZSD@1236|Gammaproteobacteria,1XNGP@135619|Oceanospirillales 135619|Oceanospirillales E Creatinase/Prolidase N-terminal domain - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016812,GO:0019752,GO:0032787,GO:0042399,GO:0042400,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046700,GO:0071704,GO:0072329,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.4.13.9,3.5.4.44 ko:K01271,ko:K15783 ko00260,ko01100,map00260,map01100 - R09800 RC02661 ko00000,ko00001,ko01000,ko01002 - - - Creatinase_N,Peptidase_M24 k141_3139_2 42565.FP66_03095 2.48e-48 166.0 COG1167@1|root,COG1167@2|Bacteria,1MUJE@1224|Proteobacteria,1RXYA@1236|Gammaproteobacteria,1XP46@135619|Oceanospirillales 135619|Oceanospirillales K transcriptional regulator - - - - - - - - - - - - Aminotran_1_2,GntR k141_940_1 796606.BMMGA3_01490 2.03e-76 235.0 COG3266@1|root,COG3266@2|Bacteria,1V5SZ@1239|Firmicutes,4HHMS@91061|Bacilli,1ZFVC@1386|Bacillus 91061|Bacilli S SAF - - - - - - - - - - - - ChapFlgA,SAF k141_14207_1 1042377.AFPJ01000010_gene1485 2.97e-63 197.0 COG0776@1|root,COG0776@2|Bacteria,1RFWH@1224|Proteobacteria,1S5GE@1236|Gammaproteobacteria,4676X@72275|Alteromonadaceae 1236|Gammaproteobacteria L Bacterial DNA-binding protein VL23_14575 - - - - - - - - - - - Bac_DNA_binding k141_10420_1 218284.CCDN010000002_gene2016 9.89e-198 556.0 COG0064@1|root,COG0064@2|Bacteria,1TPG3@1239|Firmicutes,4HAFB@91061|Bacilli,1ZB3K@1386|Bacillus 91061|Bacilli J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatB GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 ko:K02434 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - GatB_N,GatB_Yqey k141_36324_2 1499684.CCNP01000023_gene3048 2.42e-13 71.6 COG1835@1|root,COG1835@2|Bacteria,1VAIN@1239|Firmicutes,24C2B@186801|Clostridia,36GKD@31979|Clostridiaceae 186801|Clostridia I Acyltransferase family - - - - - - - - - - - - Acyl_transf_3 k141_22287_1 218284.CCDN010000001_gene1519 3.5e-19 85.9 COG0840@1|root,COG0840@2|Bacteria,1TRTV@1239|Firmicutes,4H9M1@91061|Bacilli,1ZBCT@1386|Bacillus 91061|Bacilli NT chemotaxis protein hemAT - - ko:K06595 - - - - ko00000,ko02035 - - - MCPsignal,Protoglobin k141_19906_1 218284.CCDN010000001_gene639 6.17e-104 311.0 COG0077@1|root,COG0077@2|Bacteria,1TPDN@1239|Firmicutes,4HA96@91061|Bacilli,1ZAVW@1386|Bacillus 91061|Bacilli E Prephenate dehydratase pheA GO:0003674,GO:0003824,GO:0004664,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0019438,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 4.2.1.51 ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024 R00691,R01373 RC00360 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU27900 ACT,PDT k141_6867_1 1230341.MJ3_03327 8.01e-14 73.6 COG1597@1|root,COG1597@2|Bacteria,1TQAU@1239|Firmicutes,4H9WD@91061|Bacilli 91061|Bacilli I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase dagK GO:0003674,GO:0003824,GO:0004143,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237 2.7.1.107 ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 - R02240 RC00002,RC00017 ko00000,ko00001,ko01000 - - - DAGK_cat k141_23633_1 511062.GU3_12120 6.59e-35 126.0 COG1040@1|root,COG1040@2|Bacteria,1QV41@1224|Proteobacteria,1RSAP@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis - - - - - - - - - - - - - k141_23633_2 1453501.JELR01000002_gene1014 1.33e-166 492.0 COG1199@1|root,COG1199@2|Bacteria,1MVRJ@1224|Proteobacteria,1RQ7B@1236|Gammaproteobacteria,464G6@72275|Alteromonadaceae 1236|Gammaproteobacteria KL COG1199 Rad3-related DNA helicases - - 3.6.4.12 ko:K10844 ko03022,ko03420,map03022,map03420 M00290 - - ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - DEAD_2,Helicase_C_2 k141_11670_1 1196028.ALEF01000014_gene2739 5.06e-40 147.0 COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,4HAM7@91061|Bacilli,4C680@84406|Virgibacillus 91061|Bacilli E Bacterial extracellular solute-binding proteins, family 5 Middle - - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 k141_15042_1 861299.J421_0903 1.44e-36 141.0 COG0249@1|root,COG0249@2|Bacteria,1ZST5@142182|Gemmatimonadetes 142182|Gemmatimonadetes L that it carries out the mismatch recognition step. This protein has a weak ATPase activity mutS - - ko:K03555 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V k141_27977_1 218284.CCDN010000006_gene3553 1.44e-77 237.0 COG2220@1|root,COG2220@2|Bacteria,1TRRP@1239|Firmicutes,4HBBS@91061|Bacilli,1ZQZH@1386|Bacillus 91061|Bacilli S Beta-lactamase superfamily domain - - - - - - - - - - - - Lactamase_B_2 k141_32866_1 1453501.JELR01000001_gene2020 2.04e-85 257.0 COG2968@1|root,COG2968@2|Bacteria,1RH7T@1224|Proteobacteria,1RP7T@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Oxidative stress defense protein bp26 - - ko:K09807 - - - - ko00000 - - - SIMPL k141_24651_1 1565129.JSFF01000013_gene282 7.39e-25 100.0 COG4461@1|root,COG4461@2|Bacteria,1R6Q3@1224|Proteobacteria,1S2QD@1236|Gammaproteobacteria,2Q9NS@267890|Shewanellaceae 1236|Gammaproteobacteria S Lysozyme inhibitor LprI - - - - - - - - - - - - LprI,MliC k141_19934_1 218284.CCDN010000004_gene3101 1.02e-99 304.0 COG0471@1|root,COG0471@2|Bacteria,1TSP2@1239|Firmicutes,4H9UV@91061|Bacilli,1ZARD@1386|Bacillus 91061|Bacilli P Sodium:sulfate symporter transmembrane region sdcS - - ko:K14445 - - - - ko00000,ko02000 2.A.47.1 - - Na_sulph_symp k141_9342_1 1294265.JCM21738_2723 1.2e-98 287.0 COG3576@1|root,COG3576@2|Bacteria,1V3YD@1239|Firmicutes,4HH46@91061|Bacilli,1ZG6P@1386|Bacillus 91061|Bacilli S Pyridoxamine 5'-phosphate oxidase - - - - - - - - - - - - Putative_PNPOx k141_14252_1 218284.CCDN010000011_gene4400 1.24e-88 262.0 COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,4HIIF@91061|Bacilli,1ZGBU@1386|Bacillus 91061|Bacilli S ATPase or kinase ydiB GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 - ko:K06925 - - - - ko00000,ko03016 - - - TsaE k141_11701_1 1453501.JELR01000002_gene327 3.81e-116 335.0 COG2095@1|root,COG2095@2|Bacteria,1N689@1224|Proteobacteria,1RPV0@1236|Gammaproteobacteria,4669S@72275|Alteromonadaceae 1236|Gammaproteobacteria U UPF0056 membrane protein yhgN GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K05595 - - - - ko00000,ko02000 2.A.95.1 - - MarC k141_11701_2 1129374.AJE_14150 1.92e-18 91.7 COG0500@1|root,COG2226@2|Bacteria,1N84S@1224|Proteobacteria,1S9VC@1236|Gammaproteobacteria,468DP@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_11 k141_23671_1 1461577.CCMH01000018_gene378 2.57e-30 117.0 COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,1HWNM@117743|Flavobacteriia 976|Bacteroidetes S ATPase family associated with various cellular activities (AAA) moxR - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 k141_23671_2 945713.IALB_2057 3.3e-98 297.0 COG1721@1|root,COG1721@2|Bacteria 2|Bacteria E protein (some members contain a von Willebrand factor type A (vWA) domain - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - - - - - - - - - - DUF58 k141_22331_2 218284.CCDN010000003_gene2962 2.08e-167 483.0 COG1982@1|root,COG1982@2|Bacteria,1TNZ9@1239|Firmicutes,4HBGC@91061|Bacilli,1ZBKS@1386|Bacillus 91061|Bacilli E Orn Lys Arg decarboxylase yaaO - - - - - - - - - - - OKR_DC_1,OKR_DC_1_C k141_32867_1 42565.FP66_11085 2.79e-95 289.0 COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,1RP0Q@1236|Gammaproteobacteria,1XIG9@135619|Oceanospirillales 135619|Oceanospirillales P phosphate transporter - - - ko:K03306 - - - - ko00000 2.A.20 - - PHO4 k141_17400_1 42565.FP66_14880 4.34e-131 385.0 COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,1RMJE@1236|Gammaproteobacteria,1XH27@135619|Oceanospirillales 135619|Oceanospirillales G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate gpmI - 5.4.2.12 ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000 - - - Metalloenzyme,Phosphodiest,iPGM_N k141_1895_1 1116375.VEJY3_06775 1.17e-72 221.0 COG2059@1|root,COG2059@2|Bacteria,1NMSJ@1224|Proteobacteria,1SMRJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria P overlaps another CDS with the same product name - - - ko:K07240 - - - - ko00000,ko02000 2.A.51.1 - - Chromate_transp k141_1895_2 223926.28806346 3.69e-214 604.0 COG1289@1|root,COG1289@2|Bacteria,1QJE4@1224|Proteobacteria,1THDF@1236|Gammaproteobacteria,1XU9P@135623|Vibrionales 135623|Vibrionales S Aromatic acid exporter family member 1 - - - - - - - - - - - - FUSC k141_1895_3 1116375.VEJY3_22746 1.13e-163 462.0 COG1566@1|root,COG1566@2|Bacteria,1MWG0@1224|Proteobacteria,1SKG5@1236|Gammaproteobacteria,1XU0T@135623|Vibrionales 135623|Vibrionales V Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - - - - - - - - - - HlyD_D23 k141_1895_4 223926.28806348 2.21e-36 123.0 2AWPN@1|root,31PNS@2|Bacteria,1QMC6@1224|Proteobacteria,1TJKU@1236|Gammaproteobacteria,1Y1DC@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF1656) - - - - - - - - - - - - DUF1656 k141_1895_5 1116375.VEJY3_21281 6.47e-228 631.0 COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,1RYHN@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q ABC-type transport system involved in resistance to organic solvents permease component - - - ko:K02066 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaE,STAS_2 k141_1895_6 1116375.VEJY3_21276 3.26e-165 465.0 COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,1S1PR@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q abc transporter atp-binding protein - - - ko:K02065 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - ABC_tran k141_1895_7 1116375.VEJY3_21271 4.09e-182 512.0 COG1463@1|root,COG1463@2|Bacteria,1MYEF@1224|Proteobacteria 1224|Proteobacteria Q Mammalian cell entry related domain protein - - - ko:K02067,ko:K06192 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaD k141_1895_8 1116375.VEJY3_21266 2.85e-102 300.0 COG3009@1|root,COG3009@2|Bacteria,1N9IG@1224|Proteobacteria,1SCIM@1236|Gammaproteobacteria 1236|Gammaproteobacteria S ABC-type transport auxiliary lipoprotein component - - - ko:K18480 - M00669 - - ko00000,ko00002,ko02000 3.A.1.27.1 - - ABC_trans_aux k141_16282_1 1294265.JCM21738_4236 1.23e-118 351.0 COG1785@1|root,COG1785@2|Bacteria,1TQCI@1239|Firmicutes,4HA27@91061|Bacilli,1ZB3J@1386|Bacillus 91061|Bacilli P Belongs to the alkaline phosphatase family phoB - 3.1.3.1 ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 M00126 R02135,R04620 RC00017 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 - - - Alk_phosphatase k141_24652_1 1294265.JCM21738_3659 2.49e-82 246.0 COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,4HAJB@91061|Bacilli,1ZMR2@1386|Bacillus 91061|Bacilli O Peptidase family M41 ftsH GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0030428,GO:0032502,GO:0042623,GO:0043170,GO:0043934,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - ko:K03798 - M00742 - - ko00000,ko00002,ko01000,ko01002,ko03110 - - - AAA,FtsH_ext,Peptidase_M41 k141_6925_1 1279017.AQYJ01000025_gene622 5e-39 150.0 COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1MUKF@1224|Proteobacteria,1RMW6@1236|Gammaproteobacteria,464JA@72275|Alteromonadaceae 1236|Gammaproteobacteria S DNA internalization-related competence protein ComEC Rec2 ycaI GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02238 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - Competence,DUF4131,Lactamase_B k141_27978_1 1453501.JELR01000001_gene2160 1.73e-87 272.0 COG3203@1|root,COG3203@2|Bacteria 2|Bacteria M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - - - - - - - - - - Porin_4 k141_34171_1 1042377.AFPJ01000038_gene1100 1.86e-133 399.0 COG4774@1|root,COG4774@2|Bacteria,1NMCN@1224|Proteobacteria,1T3TQ@1236|Gammaproteobacteria,46DC7@72275|Alteromonadaceae 1236|Gammaproteobacteria P TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_991_1 665952.HMPREF1015_01741 5.3e-163 468.0 COG0161@1|root,COG0161@2|Bacteria,1TP9N@1239|Firmicutes,4H9QK@91061|Bacilli,1ZR67@1386|Bacillus 91061|Bacilli H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor bioA - 2.6.1.105,2.6.1.62 ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R03231,R10699 RC00006,RC00062,RC00887 ko00000,ko00001,ko00002,ko01000,ko01007 - - iSB619.SA_RS12705 Aminotran_3 k141_25979_1 1294265.JCM21738_2979 1.3e-97 289.0 COG1404@1|root,COG1404@2|Bacteria,1V3SC@1239|Firmicutes,4HFE4@91061|Bacilli,1ZF22@1386|Bacillus 91061|Bacilli O Domain of unknown function (DUF4397) - - - - - - - - - - - - DUF4397,Gram_pos_anchor k141_18960_1 1279017.AQYJ01000026_gene283 2.42e-48 167.0 COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,464ES@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the peptidase S1C family mucD GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Trypsin_2 k141_18960_2 1042377.AFPJ01000037_gene2858 1.91e-116 339.0 COG2866@1|root,COG2866@2|Bacteria,1N9AY@1224|Proteobacteria,1RRGU@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Murein peptide amidase A mpaA GO:0000270,GO:0003674,GO:0003824,GO:0004040,GO:0004180,GO:0004181,GO:0005488,GO:0006022,GO:0006026,GO:0006027,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0009050,GO:0009056,GO:0009057,GO:0009253,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0019538,GO:0030203,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0046872,GO:0046914,GO:0061473,GO:0070011,GO:0071704,GO:0140096,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - ko:K14054 - - - - ko00000 - - iEC55989_1330.EC55989_1490,iECO103_1326.ECO103_1491 Peptidase_M14 k141_18960_3 1279017.AQYJ01000026_gene285 1.56e-156 447.0 COG4948@1|root,COG4948@2|Bacteria,1MW76@1224|Proteobacteria,1RMKS@1236|Gammaproteobacteria,466KF@72275|Alteromonadaceae 1236|Gammaproteobacteria M Mandelate racemase / muconate lactonizing enzyme, C-terminal domain ycjG GO:0003674,GO:0003824,GO:0016853,GO:0016854,GO:0016855 5.1.1.20,5.5.1.1 ko:K01856,ko:K19802 ko00361,ko00362,ko00364,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00364,map00623,map01100,map01120,map01220 M00568 R05300,R05390,R06989,R08116,R09229,R10938 RC00903,RC01038,RC01108,RC01321,RC01356,RC03309 ko00000,ko00001,ko00002,ko01000 - - iEC042_1314.EC042_1441,iECUMN_1333.ECUMN_1620 MR_MLE_C,MR_MLE_N k141_30349_1 1279017.AQYJ01000022_gene2721 1.09e-166 496.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria,465ZZ@72275|Alteromonadaceae 1236|Gammaproteobacteria P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec k141_12897_1 1121106.JQKB01000057_gene606 1.91e-34 135.0 COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,2TRPB@28211|Alphaproteobacteria,2JPWI@204441|Rhodospirillales 204441|Rhodospirillales H DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity dnaX - 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNA_pol3_gamma3,DUF3646 k141_11703_1 218284.CCDN010000007_gene3810 1.32e-71 237.0 COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,4H9RZ@91061|Bacilli,1ZBEA@1386|Bacillus 91061|Bacilli NT chemotaxis protein mcpC GO:0005575,GO:0005623,GO:0005886,GO:0006935,GO:0008150,GO:0009605,GO:0016020,GO:0040011,GO:0042221,GO:0042330,GO:0044464,GO:0050896,GO:0050918,GO:0071944 - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal,dCache_1 k141_23672_2 1042377.AFPJ01000014_gene1651 0.000696 43.5 2EPR3@1|root,33HBJ@2|Bacteria,1NH9J@1224|Proteobacteria,1SHY3@1236|Gammaproteobacteria,4699X@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_24654_2 218284.CCDN010000001_gene41 3.04e-14 71.6 COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,4H9KD@91061|Bacilli,1ZBBU@1386|Bacillus 91061|Bacilli KLT serine threonine protein kinase prkC GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 ko:K08884,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PASTA,Pkinase k141_34172_1 42565.FP66_04335 1.2e-98 289.0 COG3047@1|root,COG3047@2|Bacteria,1NUZJ@1224|Proteobacteria,1RRRC@1236|Gammaproteobacteria,1XK22@135619|Oceanospirillales 135619|Oceanospirillales M Outer membrane protein W - - - ko:K07275 - - - - ko00000 - - - OmpW k141_22333_1 218284.CCDN010000001_gene1970 9.69e-51 173.0 COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TYUA@1239|Firmicutes,4HDKK@91061|Bacilli,1ZPXC@1386|Bacillus 91061|Bacilli T helix_turn_helix, arabinose operon control protein ntrC - - ko:K07720 ko02020,map02020 M00519 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_18,Response_reg k141_22333_2 218284.CCDN010000001_gene1969 1.85e-179 499.0 COG4813@1|root,COG4813@2|Bacteria,1TPZ1@1239|Firmicutes,4HARS@91061|Bacilli,1ZC3B@1386|Bacillus 91061|Bacilli G Trehalose utilisation thuA - - - - - - - - - - - ThuA k141_16283_1 1279017.AQYJ01000029_gene3781 8.58e-67 216.0 COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,1RMWD@1236|Gammaproteobacteria,4650E@72275|Alteromonadaceae 1236|Gammaproteobacteria S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation mltG GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006807,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0030203,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0042597,GO:0043170,GO:0044425,GO:0044459,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901564 - ko:K07082 - - - - ko00000 - - - YceG k141_16283_2 1279017.AQYJ01000029_gene3780 7.44e-20 87.0 COG0115@1|root,COG0115@2|Bacteria 2|Bacteria E branched-chain-amino-acid transaminase activity pabB - 2.6.1.85,4.1.3.38 ko:K02619,ko:K03342 ko00790,map00790 - R01716,R05553 RC00010,RC01418,RC01843,RC02148 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_4,Chorismate_bind k141_1896_1 218284.CCDN010000001_gene1141 1.38e-177 524.0 COG0847@1|root,COG1199@1|root,COG0847@2|Bacteria,COG1199@2|Bacteria,1TQHQ@1239|Firmicutes,4HB2Y@91061|Bacilli,1ZAWI@1386|Bacillus 91061|Bacilli L helicase involved in DNA repair and perhaps also replication dinG - 3.6.4.12 ko:K03722 - - - - ko00000,ko01000,ko03400 - - - DEAD,Helicase_C_2,RNase_T,ResIII k141_10440_1 218284.CCDN010000009_gene4313 2.29e-103 302.0 COG2094@1|root,COG2094@2|Bacteria,1V1E6@1239|Firmicutes,4HG5E@91061|Bacilli,1ZFWT@1386|Bacillus 91061|Bacilli L Belongs to the DNA glycosylase MPG family yxlJ GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.2.2.21 ko:K03652 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Pur_DNA_glyco k141_10440_2 1424334.W822_18305 0.000455 43.9 COG3191@1|root,COG3191@2|Bacteria,1MWDP@1224|Proteobacteria,2VKAV@28216|Betaproteobacteria,3T22D@506|Alcaligenaceae 28216|Betaproteobacteria EQ Peptidase family S58 - - - - - - - - - - - - Peptidase_S58 k141_23673_1 42565.FP66_10335 7.91e-175 493.0 COG4977@1|root,COG4977@2|Bacteria,1MUDK@1224|Proteobacteria,1RP3X@1236|Gammaproteobacteria,1XIGM@135619|Oceanospirillales 135619|Oceanospirillales K transcriptional regulator - - - ko:K21826 - - - - ko00000,ko03000 - - - DJ-1_PfpI,HTH_18 k141_12898_1 1288826.MSNKSG1_13987 3.04e-101 300.0 COG0583@1|root,COG0583@2|Bacteria,1MX2A@1224|Proteobacteria,1RPHN@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_9346_1 1042377.AFPJ01000020_gene2059 2.53e-90 287.0 COG0457@1|root,COG0457@2|Bacteria,1MX2U@1224|Proteobacteria,1RPD2@1236|Gammaproteobacteria,464NG@72275|Alteromonadaceae 1236|Gammaproteobacteria C Cytochrome c554 and c-prime - - - - - - - - - - - - Cytochrome_C554,HEAT_2,Paired_CXXCH_1,TPR_16,TPR_19,TPR_20,TPR_8 k141_24655_1 633149.Bresu_3060 2.04e-45 156.0 COG0382@1|root,COG0382@2|Bacteria,1MVS1@1224|Proteobacteria,2TVKN@28211|Alphaproteobacteria,2KHJP@204458|Caulobacterales 204458|Caulobacterales H UbiA prenyltransferase family - - 2.5.1.133,2.5.1.62 ko:K04040 ko00860,ko01100,ko01110,map00860,map01100,map01110 - R06284,R09067,R11514,R11517 RC00020 ko00000,ko00001,ko01000,ko01006 - - - UbiA k141_24655_2 1187851.A33M_1591 3.27e-08 54.7 COG2204@1|root,COG2204@2|Bacteria,1P98K@1224|Proteobacteria,2TUM0@28211|Alphaproteobacteria,3FE3F@34008|Rhodovulum 28211|Alphaproteobacteria T Bacterial regulatory protein, Fis family ppsR - - - - - - - - - - - HTH_8,PAS,PAS_4,PAS_8,PAS_9 k141_992_1 218284.CCDN010000001_gene749 2.12e-270 755.0 COG1480@1|root,COG1480@2|Bacteria,1TR1A@1239|Firmicutes,4HAEZ@91061|Bacilli,1ZANS@1386|Bacillus 91061|Bacilli S membrane-associated HD superfamily hydrolase yqfF - - ko:K07037 - - - - ko00000 - - - 7TM-7TMR_HD,7TMR-HDED,HD k141_37560_2 1116375.VEJY3_21731 0.0 888.0 COG1119@1|root,COG1119@2|Bacteria,1MVVM@1224|Proteobacteria,1RMXK@1236|Gammaproteobacteria,1XT5Q@135623|Vibrionales 135623|Vibrionales P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA - - - ko:K05776 ko02010,map02010 M00189 - - ko00000,ko00001,ko00002,ko02000 - - - ABC_tran k141_37560_3 1219076.N646_4561 4.03e-263 731.0 COG4943@1|root,COG4943@2|Bacteria,1QU9U@1224|Proteobacteria,1T1QU@1236|Gammaproteobacteria,1XWJX@135623|Vibrionales 135623|Vibrionales T Putative diguanylate phosphodiesterase - - - - - - - - - - - - CSS-motif,EAL k141_37560_4 223926.28808759 1.99e-154 436.0 COG1414@1|root,COG1414@2|Bacteria,1R57R@1224|Proteobacteria,1S4GT@1236|Gammaproteobacteria,1XSUP@135623|Vibrionales 135623|Vibrionales K Transcriptional regulator - - - - - - - - - - - - HTH_11,HTH_20,HTH_IclR,IclR k141_37560_5 223926.28808758 6.56e-127 366.0 COG0010@1|root,COG0010@2|Bacteria,1QJHE@1224|Proteobacteria,1THHA@1236|Gammaproteobacteria,1XVV5@135623|Vibrionales 135623|Vibrionales E COG0010 Arginase agmatinase formimionoglutamate hydrolase, arginase family - - - - - - - - - - - - Arginase k141_18963_1 218284.CCDN010000001_gene532 2.12e-08 54.3 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,4H9NS@91061|Bacilli,1ZCF9@1386|Bacillus 91061|Bacilli G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family gapB GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016491,GO:0016620,GO:0016903,GO:0019318,GO:0019319,GO:0036094,GO:0043891,GO:0044238,GO:0044281,GO:0044283,GO:0046364,GO:0048037,GO:0050661,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N k141_11705_1 700598.Niako_6263 2.39e-42 149.0 COG1082@1|root,COG1082@2|Bacteria,4NJ3Z@976|Bacteroidetes,1IXDA@117747|Sphingobacteriia 976|Bacteroidetes G Xylose isomerase-like TIM barrel - - - - - - - - - - - - AP_endonuc_2 k141_19937_1 1121943.KB899997_gene1712 1.33e-137 394.0 COG0287@1|root,COG0287@2|Bacteria,1QN63@1224|Proteobacteria,1T4EC@1236|Gammaproteobacteria,1XP2D@135619|Oceanospirillales 135619|Oceanospirillales E Phosphogluconate dehydrogenase (decarboxylating) C-term - - - - - - - - - - - - F420_oxidored,PGDH_C k141_24656_1 218284.CCDN010000001_gene756 3.02e-134 390.0 COG0423@1|root,COG0423@2|Bacteria,1TP94@1239|Firmicutes,4HB9A@91061|Bacilli,1ZCAP@1386|Bacillus 91061|Bacilli J Catalyzes the attachment of glycine to tRNA(Gly) glyQS GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.14 ko:K01880 ko00970,map00970 M00359,M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - iSB619.SA_RS07880 HGTP_anticodon,tRNA-synt_2b k141_3171_1 1116375.VEJY3_14560 2.59e-124 365.0 COG2704@1|root,COG2704@2|Bacteria,1MVHH@1224|Proteobacteria,1RPTE@1236|Gammaproteobacteria,1XT7X@135623|Vibrionales 135623|Vibrionales S Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane dcuA - - ko:K07791 - - - - ko00000,ko02000 2.A.13.1 - - DcuA_DcuB k141_32871_1 1279017.AQYJ01000025_gene573 1.53e-82 255.0 COG3156@1|root,COG3156@2|Bacteria,1RAQM@1224|Proteobacteria,1S2N8@1236|Gammaproteobacteria,465H2@72275|Alteromonadaceae 1236|Gammaproteobacteria U COG3156 Type II secretory pathway, component PulK gspK GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - ko:K02460 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSK k141_28270_1 240302.BN982_00805 4.96e-12 66.2 COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli,3NEFQ@45667|Halobacillus 91061|Bacilli G phosphotransferase system, EIIB sacP GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563 2.7.1.211 ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 M00269 R00811 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.1,4.A.1.2.10,4.A.1.2.12,4.A.1.2.9 - iYO844.BSU38050 PTS_EIIB,PTS_EIIC k141_28270_2 218284.CCDN010000001_gene642 5.09e-32 125.0 COG0029@1|root,COG0029@2|Bacteria,1UHSP@1239|Firmicutes,4H9ZZ@91061|Bacilli,1ZBIE@1386|Bacillus 91061|Bacilli H Catalyzes the oxidation of L-aspartate to iminoaspartate nadB - 1.4.3.16 ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 M00115 R00357,R00481 RC00006,RC02566 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C k141_21224_1 218284.CCDN010000002_gene2602 7.54e-124 361.0 COG1063@1|root,COG1063@2|Bacteria,1TPIW@1239|Firmicutes,4HB2G@91061|Bacilli,1ZB9D@1386|Bacillus 91061|Bacilli E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases adhB - 1.1.1.1,1.1.1.284 ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 - R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_N_assoc,ADH_zinc_N k141_17729_1 218284.CCDN010000001_gene642 1.85e-95 293.0 COG0029@1|root,COG0029@2|Bacteria,1UHSP@1239|Firmicutes,4H9ZZ@91061|Bacilli,1ZBIE@1386|Bacillus 91061|Bacilli H Catalyzes the oxidation of L-aspartate to iminoaspartate nadB - 1.4.3.16 ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 M00115 R00357,R00481 RC00006,RC02566 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C k141_30549_1 42565.FP66_14740 1.65e-134 390.0 COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,1RMI2@1236|Gammaproteobacteria,1XHK6@135619|Oceanospirillales 135619|Oceanospirillales E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine lysA - 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N,Orn_DAP_Arg_deC k141_21225_1 1380387.JADM01000018_gene3346 1.05e-46 153.0 COG1539@1|root,COG1539@2|Bacteria,1MZ8Z@1224|Proteobacteria,1S9B2@1236|Gammaproteobacteria,1XKFN@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin folB - 1.13.11.81,4.1.2.25,5.1.99.8 ko:K01633 ko00790,ko01100,map00790,map01100 M00126,M00840 R03504,R11037,R11073 RC00721,RC00943,RC01479,RC03333,RC03334 ko00000,ko00001,ko00002,ko01000 - - - FolB k141_33158_1 402881.Plav_2386 1.23e-125 374.0 COG3637@1|root,COG3637@2|Bacteria,1QUUK@1224|Proteobacteria,2TW8A@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Alginate export - - - - - - - - - - - - Alginate_exp k141_33158_2 1042377.AFPJ01000016_gene122 3.63e-57 187.0 COG3713@1|root,COG4704@1|root,COG3713@2|Bacteria,COG4704@2|Bacteria 2|Bacteria M MltA-interacting MipA family protein mipA - - ko:K07274 - - - - ko00000,ko02000 9.B.99.1 - - DUF2141,MipA k141_31705_1 218284.CCDN010000001_gene1068 9.37e-84 252.0 COG3601@1|root,COG3601@2|Bacteria,1V4BW@1239|Firmicutes,4HHFT@91061|Bacilli,1ZG7K@1386|Bacillus 91061|Bacilli U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins ribU GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656 - - - - - - - - - - ECF_trnsprt k141_3441_1 42565.FP66_09955 4.31e-123 353.0 COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,1S46A@1236|Gammaproteobacteria,1XJNP@135619|Oceanospirillales 135619|Oceanospirillales J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ctc - - ko:K02897 ko03010,map03010 M00178 - - ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L25p,Ribosomal_TL5_C k141_10661_1 935837.JAEK01000024_gene1037 8.9e-103 299.0 COG0094@1|root,COG0094@2|Bacteria,1TPE0@1239|Firmicutes,4HBAX@91061|Bacilli,1ZB6T@1386|Bacillus 91061|Bacilli J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits rplE GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02931 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L5,Ribosomal_L5_C k141_4620_1 1116375.VEJY3_24196 3.2e-210 590.0 COG1167@1|root,COG1167@2|Bacteria,1MVGT@1224|Proteobacteria,1RPFK@1236|Gammaproteobacteria,1XTBA@135623|Vibrionales 135623|Vibrionales K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs - - - ko:K00375 - - - - ko00000,ko03000 - - - Aminotran_1_2,GntR k141_4620_2 1116375.VEJY3_24201 1.33e-146 416.0 COG0730@1|root,COG0730@2|Bacteria 2|Bacteria S response to heat - - - ko:K07090 - - - - ko00000 - - - TauE k141_4620_3 1116375.VEJY3_24206 4.4e-175 489.0 COG4221@1|root,COG4221@2|Bacteria,1MUF8@1224|Proteobacteria,1RMKM@1236|Gammaproteobacteria,1XUEP@135623|Vibrionales 135623|Vibrionales S Belongs to the short-chain dehydrogenases reductases (SDR) family - - 1.1.1.313 ko:K15373 ko00430,ko01100,map00430,map01100 - R02600 RC00087 ko00000,ko00001,ko01000 - - - adh_short k141_4620_4 29495.EA26_10205 7.4e-130 369.0 COG0450@1|root,COG0450@2|Bacteria,1MWPY@1224|Proteobacteria,1RN4S@1236|Gammaproteobacteria,1XUVP@135623|Vibrionales 135623|Vibrionales O Alkyl hydroperoxide reductase ahpC - 1.11.1.15 ko:K03386 ko04214,map04214 - - - ko00000,ko00001,ko01000,ko04147 - - - 1-cysPrx_C,AhpC-TSA k141_4620_5 1116375.VEJY3_24246 0.0 979.0 COG3634@1|root,COG3634@2|Bacteria,1MUKD@1224|Proteobacteria,1RNC7@1236|Gammaproteobacteria,1XT7A@135623|Vibrionales 135623|Vibrionales O COG3634 Alkyl hydroperoxide reductase, large subunit ahpF - - ko:K03387 - - - - ko00000,ko01000 - - - Pyr_redox_2,Thioredoxin_3 k141_4620_6 1116375.VEJY3_13360 5.41e-132 379.0 COG2968@1|root,COG2968@2|Bacteria,1RH7T@1224|Proteobacteria,1RP7T@1236|Gammaproteobacteria,1XUSG@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF541) - - - ko:K09807 - - - - ko00000 - - - SIMPL k141_4620_7 223926.28807605 1.04e-192 537.0 COG0583@1|root,COG0583@2|Bacteria,1MWUP@1224|Proteobacteria,1RNIC@1236|Gammaproteobacteria,1XSZG@135623|Vibrionales 135623|Vibrionales K Controls the transcription of genes involved in arginine and lysine metabolism argP GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 - ko:K05596 - - - - ko00000,ko03000,ko03036 - - - HTH_1,LysR_substrate k141_4620_8 223926.28807606 2.48e-133 379.0 COG1279@1|root,COG1279@2|Bacteria,1RD6B@1224|Proteobacteria,1RR03@1236|Gammaproteobacteria,1XUSK@135623|Vibrionales 135623|Vibrionales S COG1279 Lysine efflux permease argO - - ko:K06895 - - - - ko00000,ko02000 2.A.75.1 - - LysE k141_30550_1 218284.CCDN010000002_gene2213 6.3e-20 80.1 2EG6C@1|root,339Y6@2|Bacteria,1VPY7@1239|Firmicutes,4HRNE@91061|Bacilli,1ZK0I@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2639) yflJ - - - - - - - - - - - DUF2639 k141_29719_1 223926.28808704 6.85e-36 125.0 COG3175@1|root,COG3175@2|Bacteria,1RDTU@1224|Proteobacteria,1S5XA@1236|Gammaproteobacteria,1XVB6@135623|Vibrionales 135623|Vibrionales O COG3175 Cytochrome oxidase assembly factor coxG - - ko:K02258 ko00190,ko01100,ko04714,map00190,map01100,map04714 M00154 - - ko00000,ko00001,ko00002,ko03029 3.D.4.8 - - CtaG_Cox11 k141_29719_2 1116375.VEJY3_21951 1.99e-204 566.0 COG1845@1|root,COG1845@2|Bacteria,1MUCK@1224|Proteobacteria,1RN9D@1236|Gammaproteobacteria,1XSND@135623|Vibrionales 135623|Vibrionales C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3 coxC - 1.9.3.1 ko:K02276 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.4,3.D.4.6 - - COX3 k141_29719_3 1116375.VEJY3_21941 3e-151 429.0 COG3346@1|root,COG3346@2|Bacteria,1MZUH@1224|Proteobacteria,1S8S0@1236|Gammaproteobacteria,1XXKF@135623|Vibrionales 135623|Vibrionales S SURF1-like protein VVA1112 - - - - - - - - - - - SURF1 k141_29719_4 1116375.VEJY3_21936 2e-99 291.0 COG1999@1|root,COG1999@2|Bacteria,1N6R6@1224|Proteobacteria,1S85U@1236|Gammaproteobacteria,1XXWZ@135623|Vibrionales 135623|Vibrionales S signal sequence binding VVA1110 - - - - - - - - - - - - k141_29719_5 1116375.VEJY3_21931 3.95e-213 592.0 COG1612@1|root,COG1612@2|Bacteria,1MVJ4@1224|Proteobacteria,1RQWB@1236|Gammaproteobacteria,1XTST@135623|Vibrionales 135623|Vibrionales O protein required for cytochrome oxidase assembly - - - ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 M00154 R07412 RC00769 ko00000,ko00001,ko00002,ko03029 3.D.4.4 - - COX15-CtaA k141_15281_7 1116375.VEJY3_01480 1.21e-107 311.0 COG3495@1|root,COG3495@2|Bacteria,1RB8H@1224|Proteobacteria,1S8DT@1236|Gammaproteobacteria,1XX0Z@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria - - - ko:K09950 - - - - ko00000 - - - DUF3299 k141_2270_1 218284.CCDN010000006_gene3673 2.88e-127 370.0 COG0626@1|root,COG0626@2|Bacteria,1TPC7@1239|Firmicutes,4HAFQ@91061|Bacilli,1ZAR9@1386|Bacillus 91061|Bacilli E cystathionine - - 2.5.1.48 ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017 R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946 RC00020,RC00056,RC00069,RC00420,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000 - - - Cys_Met_Meta_PP k141_37898_1 1236542.BALM01000043_gene454 4.87e-102 307.0 COG0657@1|root,COG0657@2|Bacteria,1NEXK@1224|Proteobacteria,1RYVV@1236|Gammaproteobacteria,2Q9IG@267890|Shewanellaceae 1236|Gammaproteobacteria I PFAM Alpha beta hydrolase fold-3 domain protein - - - ko:K01066 - - - - ko00000,ko01000 - - - Abhydrolase_3,PNP_UDP_1 k141_16588_1 315750.BPUM_1932 2.31e-19 80.1 2E6UK@1|root,331EA@2|Bacteria,1VF2M@1239|Firmicutes,4HPQ1@91061|Bacilli,1ZKC4@1386|Bacillus 91061|Bacilli S Zinc-finger ypeQ - - - - - - - - - - - zf-C2HCIx2C k141_16588_2 218284.CCDN010000001_gene1181 1.02e-93 278.0 COG0328@1|root,COG0328@2|Bacteria,1V3K2@1239|Firmicutes,4HE8H@91061|Bacilli,1ZDMZ@1386|Bacillus 91061|Bacilli L COG0328 Ribonuclease HI ypeP - 3.1.26.4 ko:K03469 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RVT_3 k141_31745_1 1279017.AQYJ01000023_gene3170 2.58e-203 577.0 COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,1RM98@1236|Gammaproteobacteria,465ZI@72275|Alteromonadaceae 1236|Gammaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoC GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 ko:K13378 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - iECDH10B_1368.ECDH10B_2448,iECDH1ME8569_1439.ECDH1ME8569_2223,iETEC_1333.ETEC_2421,iEcDH1_1363.EcDH1_1371,iPC815.YPO2553,iUMNK88_1353.UMNK88_2836 Complex1_30kDa,Complex1_49kDa k141_31745_2 301.JNHE01000033_gene954 1.6e-63 200.0 COG0377@1|root,COG0377@2|Bacteria,1MUI2@1224|Proteobacteria,1RP4R@1236|Gammaproteobacteria,1YESW@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoB GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008137,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0034220,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0048037,GO:0050136,GO:0051179,GO:0051234,GO:0051536,GO:0051539,GO:0051540,GO:0055085,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1902600,GO:1990204 1.6.5.3 ko:K00331 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - iYL1228.KPN_02677 Oxidored_q6 k141_8100_1 1280001.BAOA01000115_gene135 9.6e-50 160.0 2AW99@1|root,31N4K@2|Bacteria,1QJW1@1224|Proteobacteria,1THXQ@1236|Gammaproteobacteria,1XXUK@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_8100_2 1219076.N646_0422 1.29e-147 418.0 COG3063@1|root,COG3063@2|Bacteria,1MXPC@1224|Proteobacteria,1RY78@1236|Gammaproteobacteria,1XSMH@135623|Vibrionales 135623|Vibrionales NU COG3063 Tfp pilus assembly protein PilF pilF - - ko:K02656 - - - - ko00000,ko02035,ko02044 - - - TPR_12,TPR_16,TPR_17,TPR_19,TPR_2,TPR_6,TPR_8 k141_8100_3 223926.28806743 7.77e-232 637.0 COG1897@1|root,COG1897@2|Bacteria,1MV64@1224|Proteobacteria,1RM7T@1236|Gammaproteobacteria,1XTIN@135623|Vibrionales 135623|Vibrionales E Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine metAS GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0008899,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016750,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.46 ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 M00017 R01777 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 - - - HTS k141_8100_4 1116375.VEJY3_08205 1.82e-64 198.0 2B63Z@1|root,31Z0Q@2|Bacteria,1QK57@1224|Proteobacteria,1TI8B@1236|Gammaproteobacteria,1XYMP@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_4670_1 634956.Geoth_3462 7.68e-26 105.0 COG2138@1|root,COG2138@2|Bacteria,1TRDV@1239|Firmicutes,4H9RT@91061|Bacilli,1WER8@129337|Geobacillus 91061|Bacilli S cobalamin (vitamin B12) biosynthesis CbiX sirB - 4.99.1.4 ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R02864 RC01012 ko00000,ko00001,ko00002,ko01000 - - - CbiX k141_4670_2 935837.JAEK01000005_gene4538 8.29e-26 100.0 COG1648@1|root,COG1648@2|Bacteria,1VA2E@1239|Firmicutes,4HIRG@91061|Bacilli,1ZHMG@1386|Bacillus 91061|Bacilli H Siroheme synthase sirC - 1.3.1.76,4.99.1.4 ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02864,R03947 RC01012,RC01034 ko00000,ko00001,ko00002,ko01000 - - - NAD_binding_7,Sirohm_synth_M k141_2271_2 1279017.AQYJ01000027_gene1546 1.02e-47 165.0 COG3515@1|root,COG3515@2|Bacteria,1MY80@1224|Proteobacteria,1T0A1@1236|Gammaproteobacteria,466QN@72275|Alteromonadaceae 1236|Gammaproteobacteria S ImpA, N-terminal, type VI secretion system impA - - ko:K11902 ko02025,map02025 M00334 - - ko00000,ko00001,ko00002,ko02044 - - - ImpA_N k141_16589_1 218284.CCDN010000005_gene3373 2.2e-141 407.0 COG0436@1|root,COG0436@2|Bacteria,1TQD6@1239|Firmicutes,4HAHQ@91061|Bacilli,1ZBB2@1386|Bacillus 91061|Bacilli E Aminotransferase mtnE - - ko:K08969 ko00270,ko01100,map00270,map01100 M00034 R07396 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k141_31746_1 218284.CCDN010000002_gene2922 1.16e-30 112.0 29NVC@1|root,309TF@2|Bacteria,1U5NJ@1239|Firmicutes,4IFD5@91061|Bacilli,1ZKA7@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_30592_2 1279017.AQYJ01000024_gene868 3.23e-65 201.0 COG3791@1|root,COG3791@2|Bacteria,1RHWZ@1224|Proteobacteria,1S4HQ@1236|Gammaproteobacteria,4688I@72275|Alteromonadaceae 1236|Gammaproteobacteria S Glutathione-dependent formaldehyde-activating enzyme - - - - - - - - - - - - GFA k141_30592_3 1268239.PALB_18920 2.08e-24 101.0 COG0676@1|root,COG0676@2|Bacteria,1Q7VN@1224|Proteobacteria,1RQK0@1236|Gammaproteobacteria,2PZCD@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria G Belongs to the glucose-6-phosphate 1-epimerase family yeaD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716 5.1.3.15 ko:K01792 ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130 - R02739 RC00563 ko00000,ko00001,ko01000 - - - Aldose_epim k141_15282_1 1294265.JCM21738_999 1.33e-103 302.0 COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,4HA7D@91061|Bacilli,1ZARN@1386|Bacillus 91061|Bacilli T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - ko:K02483 - - - - ko00000,ko02022 - - - Response_reg,Trans_reg_C k141_15282_2 1294265.JCM21738_1000 3.41e-39 138.0 COG3391@1|root,COG3391@2|Bacteria,1VRT8@1239|Firmicutes,4HTU7@91061|Bacilli,1ZQYD@1386|Bacillus 91061|Bacilli S amine dehydrogenase activity - - - - - - - - - - - - - k141_8101_1 1453501.JELR01000001_gene2673 5.46e-66 203.0 COG0526@1|root,COG0526@2|Bacteria,1RI3N@1224|Proteobacteria,1S5YV@1236|Gammaproteobacteria,466IK@72275|Alteromonadaceae 1236|Gammaproteobacteria CO Thiol disulfide interchange protein dsbE GO:0003674,GO:0003756,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015036,GO:0016020,GO:0016043,GO:0016491,GO:0016667,GO:0016853,GO:0016860,GO:0016864,GO:0017004,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0055114,GO:0065003,GO:0071840,GO:0071944,GO:0098552,GO:0098567,GO:0140096 - ko:K02199 - - - - ko00000,ko03110 - - - Redoxin k141_33202_1 1049564.TevJSym_bb00050 5.25e-113 344.0 COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,1S0WV@1236|Gammaproteobacteria,1J5KF@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases korA - 1.2.7.11,1.2.7.3 ko:K00174 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - PFOR_II,POR,POR_N k141_31747_1 1294265.JCM21738_5027 8.23e-83 258.0 COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,4H9T1@91061|Bacilli,1ZE6U@1386|Bacillus 91061|Bacilli M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan - - 6.3.2.13 ko:K01928 ko00300,ko00550,map00300,map00550 - R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M k141_17784_1 1219076.N646_3162 1.93e-76 241.0 COG0845@1|root,COG0845@2|Bacteria,1MUI8@1224|Proteobacteria,1RNK4@1236|Gammaproteobacteria,1XVAQ@135623|Vibrionales 135623|Vibrionales M COG0845 Membrane-fusion protein - - - ko:K02022 - - - - ko00000 - - - Biotin_lipoyl_2,HlyD,HlyD_3 k141_17784_2 674977.VMC_08740 2.51e-294 813.0 COG4618@1|root,COG4618@2|Bacteria,1NTI5@1224|Proteobacteria,1T1HR@1236|Gammaproteobacteria,1XUAM@135623|Vibrionales 135623|Vibrionales V COG4618 ABC-type protease lipase transport system, ATPase and permease components - - - ko:K06148 - - - - ko00000,ko02000 3.A.1 - - ABC_membrane,ABC_tran k141_37901_1 796606.BMMGA3_10565 1.08e-88 288.0 COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H9SA@91061|Bacilli,1ZAXY@1386|Bacillus 91061|Bacilli M penicillin-binding protein ponA GO:0005575,GO:0005576 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase,fn3 k141_33203_1 1449126.JQKL01000036_gene1950 5.34e-18 89.0 COG2931@1|root,COG2931@2|Bacteria 2|Bacteria Q calcium- and calmodulin-responsive adenylate cyclase activity - - - - - - - - - - - - FG-GAP,HemolysinCabind k141_8103_1 1395516.PMO01_05445 2.75e-50 168.0 COG4385@1|root,COG4385@2|Bacteria 2|Bacteria T Tail protein - - - - - - - - - - - - Tail_P2_I k141_37902_1 1453501.JELR01000001_gene3043 3.89e-13 68.6 COG1589@1|root,COG1589@2|Bacteria,1N0T7@1224|Proteobacteria,1S9FJ@1236|Gammaproteobacteria,467QJ@72275|Alteromonadaceae 1236|Gammaproteobacteria D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly ftsQ GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0042802,GO:0043093,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 - ko:K03589 ko04112,map04112 - - - ko00000,ko00001,ko03036 - - - FtsQ,POTRA_1 k141_33204_1 1453501.JELR01000001_gene1866 6.23e-86 266.0 COG0642@1|root,COG2205@2|Bacteria,1QTVU@1224|Proteobacteria,1RPFY@1236|Gammaproteobacteria,4653U@72275|Alteromonadaceae 1236|Gammaproteobacteria T Signal transduction histidine kinase phoQ GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010350,GO:0016020,GO:0016021,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0031224,GO:0031226,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0035556,GO:0036211,GO:0042578,GO:0042594,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046777,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071496,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.7.13.3 ko:K07637 ko01503,ko02020,map01503,map02020 M00444,M00709,M00721,M00723,M00724,M00744 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 - - - HATPase_c,HisKA,PhoQ_Sensor k141_21282_1 218284.CCDN010000001_gene1695 4.78e-86 281.0 COG0553@1|root,COG4715@1|root,COG0553@2|Bacteria,COG4715@2|Bacteria,1TPFZ@1239|Firmicutes,4HAIF@91061|Bacilli,1ZBZT@1386|Bacillus 91061|Bacilli L COG0553 Superfamily II DNA RNA helicases, SNF2 family snf - - - - - - - - - - - Helicase_C,SNF2_N,SNF2_assoc,SWIM k141_4672_3 1042377.AFPJ01000043_gene868 1.14e-68 211.0 COG0360@1|root,COG0360@2|Bacteria,1RH82@1224|Proteobacteria,1S5VU@1236|Gammaproteobacteria,4677Q@72275|Alteromonadaceae 1236|Gammaproteobacteria J Binds together with S18 to 16S ribosomal RNA rpsF GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048027,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02990 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S6 k141_4672_4 1220583.GOACH_04_02520 4.72e-13 71.2 COG4757@1|root,COG4757@2|Bacteria,2ICF8@201174|Actinobacteria,4GERP@85026|Gordoniaceae 201174|Actinobacteria S Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_1,Hydrolase_4 k141_28326_1 42565.FP66_07550 1.6e-153 446.0 COG0608@1|root,COG0608@2|Bacteria,1MU1M@1224|Proteobacteria,1RMF4@1236|Gammaproteobacteria,1XI04@135619|Oceanospirillales 135619|Oceanospirillales L exonuclease recJ recJ - - ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1 k141_37903_2 1279038.KB907337_gene208 1.03e-14 72.0 COG3080@1|root,COG3080@2|Bacteria,1RDZD@1224|Proteobacteria,2UI14@28211|Alphaproteobacteria,2JUB3@204441|Rhodospirillales 204441|Rhodospirillales C Fumarate reductase subunit D - - - - - - - - - - - - Fumarate_red_D k141_2275_2 1294265.JCM21738_3990 5.36e-20 84.3 2D69E@1|root,32TKR@2|Bacteria,1VCRS@1239|Firmicutes,4HMFA@91061|Bacilli,1ZAXR@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - Cu_amine_oxidN1 k141_33206_1 1294265.JCM21738_4903 3.09e-26 106.0 COG1033@1|root,COG1033@2|Bacteria,1VSWA@1239|Firmicutes,4HHPY@91061|Bacilli,1ZIDI@1386|Bacillus 91061|Bacilli S MMPL family - - - ko:K07003 - - - - ko00000 - - - MMPL k141_33206_2 1294265.JCM21738_4902 5.55e-49 165.0 COG1033@1|root,COG1033@2|Bacteria,1VSWA@1239|Firmicutes,4HHPY@91061|Bacilli,1ZIDI@1386|Bacillus 91061|Bacilli S MMPL family - - - - - - - - - - - - MMPL k141_8104_2 945713.IALB_0547 1.5e-50 165.0 COG2406@1|root,COG2406@2|Bacteria 2|Bacteria S Ferritin, Dps family protein - - 1.16.3.1 ko:K03594 ko00860,map00860 - R00078 RC02758 ko00000,ko00001,ko01000 - - - Ferritin k141_28327_1 1453501.JELR01000002_gene698 2.04e-114 340.0 COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,1RN0W@1236|Gammaproteobacteria,464SX@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0006 Xaa-Pro aminopeptidase pepP - 3.4.11.9 ko:K01262 - - - - ko00000,ko01000,ko01002 - - - AMP_N,Peptidase_M24 k141_37904_1 1122194.AUHU01000007_gene179 6.48e-128 369.0 COG3507@1|root,COG3507@2|Bacteria,1QBSN@1224|Proteobacteria,1S1V5@1236|Gammaproteobacteria,465D7@72275|Alteromonadaceae 1236|Gammaproteobacteria G Belongs to the glycosyl hydrolase 43 family - - - - - - - - - - - - Glyco_hydro_43 k141_15284_1 1116375.VEJY3_03225 9.39e-134 403.0 COG0457@1|root,COG0457@2|Bacteria,1RDRI@1224|Proteobacteria,1S3PB@1236|Gammaproteobacteria,1XTIH@135623|Vibrionales 135623|Vibrionales S COG0457 FOG TPR repeat - - - - - - - - - - - - TPR_12 k141_28328_1 218284.CCDN010000001_gene536 1.23e-81 255.0 COG3611@1|root,COG3611@2|Bacteria,1TSBB@1239|Firmicutes,4H9RI@91061|Bacilli,1ZBJY@1386|Bacillus 91061|Bacilli L Membrane attachment protein dnaB - - ko:K03346 - - - - ko00000,ko03032 - - - DnaB_2 k141_16593_2 1279017.AQYJ01000023_gene3127 2.15e-96 283.0 COG1959@1|root,COG1959@2|Bacteria,1RDA4@1224|Proteobacteria,1S3RW@1236|Gammaproteobacteria,466UA@72275|Alteromonadaceae 1236|Gammaproteobacteria K Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins iscR GO:0003674,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 - ko:K13643 - - - - ko00000,ko03000 - - - Rrf2 k141_16593_3 1279017.AQYJ01000023_gene3126 1.47e-168 473.0 COG0565@1|root,COG0565@2|Bacteria,1N47Y@1224|Proteobacteria,1RPD3@1236|Gammaproteobacteria,465US@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA trmJ - 2.1.1.200 ko:K02533,ko:K15396 - - - - ko00000,ko01000,ko03016 - - - SpoU_methylase k141_21285_1 218284.CCDN010000001_gene402 2.48e-07 49.7 2C4Q6@1|root,2ZT3S@2|Bacteria,1W3JN@1239|Firmicutes,4I0GR@91061|Bacilli,1ZPKT@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_21285_2 1294265.JCM21738_3229 1.52e-25 97.4 COG1811@1|root,COG1811@2|Bacteria,1UH19@1239|Firmicutes,4HB4E@91061|Bacilli,1ZBSK@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF554) ydfK - - ko:K07150 - - - - ko00000 - - - DUF554 k141_36591_4 1101195.Meth11DRAFT_0223 8.39e-29 108.0 COG2076@1|root,COG2076@2|Bacteria,1NAUF@1224|Proteobacteria,2WE9Q@28216|Betaproteobacteria 28216|Betaproteobacteria P Small Multidrug Resistance protein - - - - - - - - - - - - EamA,Multi_Drug_Res k141_36591_5 754476.Q7A_1422 3.11e-146 433.0 COG0382@1|root,COG0560@1|root,COG0382@2|Bacteria,COG0560@2|Bacteria,1MXCM@1224|Proteobacteria,1RRWB@1236|Gammaproteobacteria,46214@72273|Thiotrichales 72273|Thiotrichales H UbiA prenyltransferase family - - - - - - - - - - - - HAD,UbiA k141_36591_6 1124780.ANNU01000062_gene568 8.88e-57 191.0 2D326@1|root,32TE3@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Sulfotransfer_1,Sulfotransfer_3 k141_36591_7 1122605.KB893637_gene3156 4.25e-44 160.0 COG0241@1|root,COG1208@1|root,COG0241@2|Bacteria,COG1208@2|Bacteria,4NFDB@976|Bacteroidetes,1IPMP@117747|Sphingobacteriia 976|Bacteroidetes JM Nucleotidyl transferase gmhB - 2.7.7.71 ko:K15669 ko00540,map00540 - R09772 RC00002 ko00000,ko00001,ko01000 - - - CBS,NTP_transferase k141_36591_8 349521.HCH_06182 1.05e-81 248.0 COG0279@1|root,COG0279@2|Bacteria,1NVIE@1224|Proteobacteria,1RP6M@1236|Gammaproteobacteria,1XKC8@135619|Oceanospirillales 135619|Oceanospirillales G Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate - - 5.3.1.28 ko:K03271 ko00540,ko01100,map00540,map01100 M00064 R05645,R09768,R09769 RC00434 ko00000,ko00001,ko00002,ko01000,ko01005 - - - SIS_2 k141_36591_9 243265.plu4822 2.51e-138 403.0 COG2605@1|root,COG2605@2|Bacteria 2|Bacteria G GHMP kinase hddA - 2.7.1.168 ko:K07031 ko00540,map00540 - R09770 RC00002,RC00078 ko00000,ko00001,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N k141_36591_10 1265503.KB905168_gene1442 3.69e-78 252.0 COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,1RS5D@1236|Gammaproteobacteria,2Q6YQ@267889|Colwelliaceae 1236|Gammaproteobacteria M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1 k141_36591_11 754436.JCM19237_3633 1.33e-93 302.0 COG2605@1|root,COG3307@1|root,COG2605@2|Bacteria,COG3307@2|Bacteria,1PX0E@1224|Proteobacteria,1RPTR@1236|Gammaproteobacteria,1XTJN@135623|Vibrionales 135623|Vibrionales M COG3307 Lipid A core - O-antigen ligase and related enzymes exoQ - - - - - - - - - - - Wzy_C k141_36591_12 406818.XBJ1_2355 3.28e-106 319.0 COG4974@1|root,COG4974@2|Bacteria,1R7M0@1224|Proteobacteria,1RYKU@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_int_SAM_1,Phage_integrase k141_36591_13 1129794.C427_4187 3.45e-93 282.0 COG1943@1|root,COG1943@2|Bacteria,1P8IT@1224|Proteobacteria,1RSQC@1236|Gammaproteobacteria,4686T@72275|Alteromonadaceae 1236|Gammaproteobacteria L Sulfotransferase family - - - - - - - - - - - - Sulfotransfer_2 k141_36591_15 1537994.JQFW01000056_gene742 1.07e-62 207.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,4650W@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains prsR - - ko:K02481 - - - - ko00000,ko02022 - - - HTH_8,Response_reg,Sigma54_activat k141_13218_8 1116375.VEJY3_18256 6.11e-297 814.0 COG0402@1|root,COG0402@2|Bacteria,1MUPT@1224|Proteobacteria,1SYCI@1236|Gammaproteobacteria,1XTV5@135623|Vibrionales 135623|Vibrionales F COG0402 Cytosine deaminase and related metal-dependent hydrolases guaD - 3.5.4.3 ko:K01487 ko00230,ko01100,map00230,map01100 - R01676 RC00204 ko00000,ko00001,ko01000 - - - Amidohydro_1 k141_1241_1 1219076.N646_2771 8.98e-52 178.0 COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,1RNAZ@1236|Gammaproteobacteria,1XSYD@135623|Vibrionales 135623|Vibrionales L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseA GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494 3.1.11.6 ko:K03601 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_L,tRNA_anti_2 k141_1241_2 223926.28805600 2.11e-47 151.0 COG1198@1|root,COG1198@2|Bacteria,1NHFG@1224|Proteobacteria,1SGTI@1236|Gammaproteobacteria,1XYUA@135623|Vibrionales 135623|Vibrionales L zinc-ribbons - - - - - - - - - - - - zinc-ribbons_6 k141_1241_3 1116375.VEJY3_02805 3.5e-177 497.0 COG2872@1|root,COG2872@2|Bacteria,1MZZ3@1224|Proteobacteria,1S2IX@1236|Gammaproteobacteria,1XU5D@135623|Vibrionales 135623|Vibrionales S metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain - - 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - - k141_1241_4 1116375.VEJY3_02800 0.0 937.0 COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,1RMSF@1236|Gammaproteobacteria,1XTH0@135623|Vibrionales 135623|Vibrionales S GTPase that plays an essential role in the late steps of ribosome biogenesis der GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03977 - - - - ko00000,ko03009 - - - KH_dom-like,MMR_HSR1 k141_1241_5 1116375.VEJY3_02795 4.1e-204 573.0 COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,1RN4V@1236|Gammaproteobacteria,1XSD2@135623|Vibrionales 135623|Vibrionales M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamB GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0055114 - ko:K17713 - - - - ko00000,ko02000 1.B.33.1 - - PQQ_2,PQQ_3 k141_6114_2 1196031.ALEG01000019_gene2899 3.99e-122 353.0 COG2738@1|root,COG2738@2|Bacteria,1TPD3@1239|Firmicutes,4HB8Z@91061|Bacilli,1ZD1M@1386|Bacillus 91061|Bacilli S Zn-dependent protease yugP - - ko:K06973 - - - - ko00000 - - - Zn_peptidase_2 k141_31070_2 1232437.KL662031_gene2543 1.33e-33 127.0 COG2367@1|root,COG2367@2|Bacteria,1R6KF@1224|Proteobacteria,42YYI@68525|delta/epsilon subdivisions,2WTQR@28221|Deltaproteobacteria 28221|Deltaproteobacteria V Beta-lactamase enzyme family - - 3.5.2.6 ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 M00627,M00628 R06363 RC01499 ko00000,ko00001,ko00002,ko01000,ko01504 - - - Beta-lactamase2 k141_26314_1 218284.CCDN010000001_gene1024 2.99e-58 188.0 COG1073@1|root,COG1073@2|Bacteria,1TQYU@1239|Firmicutes,4HC4H@91061|Bacilli,1ZBDV@1386|Bacillus 91061|Bacilli S COG1073 Hydrolases of the alpha beta superfamily yqkD - - ko:K06889 - - - - ko00000 - - - Hydrolase_4 k141_26314_2 218284.CCDN010000001_gene1023 5.41e-40 140.0 COG3570@1|root,COG3570@2|Bacteria,1V5G9@1239|Firmicutes,4HH9E@91061|Bacilli,1ZFTN@1386|Bacillus 91061|Bacilli V Aminoglycoside/hydroxyurea antibiotic resistance kinase - - 2.7.1.72 ko:K04343 - M00766 R02225 RC00002,RC00078 br01600,ko00000,ko00002,ko01000,ko01504 - - - APH_6_hur k141_8477_1 1116375.VEJY3_19986 0.0 1047.0 COG2267@1|root,COG2267@2|Bacteria,1QUH9@1224|Proteobacteria,1T1YS@1236|Gammaproteobacteria,1XU7S@135623|Vibrionales 135623|Vibrionales I Bacterial virulence factor lipase N-terminal - GO:0003674,GO:0003824,GO:0006629,GO:0008150,GO:0008152,GO:0009056,GO:0016042,GO:0016298,GO:0016787,GO:0016788,GO:0044238,GO:0071704,GO:1901575 - - - - - - - - - - Lipase_bact_N k141_8477_2 1116375.VEJY3_19981 7.13e-251 694.0 COG2067@1|root,COG2067@2|Bacteria,1MUU4@1224|Proteobacteria,1RQZJ@1236|Gammaproteobacteria,1XTAE@135623|Vibrionales 135623|Vibrionales I long-chain fatty acid transport protein - - - ko:K06076 - - - - ko00000,ko02000 1.B.9 - - Toluene_X k141_8477_4 1116375.VEJY3_19971 1.36e-170 478.0 COG0501@1|root,COG0501@2|Bacteria,1MUNA@1224|Proteobacteria,1RMZ6@1236|Gammaproteobacteria,1XTEI@135623|Vibrionales 135623|Vibrionales O Zn-dependent protease with chaperone function - - - - - - - - - - - - Peptidase_M48 k141_8477_5 223926.28809163 1e-93 274.0 COG2050@1|root,COG2050@2|Bacteria,1RGVP@1224|Proteobacteria,1S5WY@1236|Gammaproteobacteria,1XWX9@135623|Vibrionales 135623|Vibrionales Q protein possibly involved in aromatic compounds catabolism ydiI - - - - - - - - - - - 4HBT k141_8477_6 223926.28809164 3.2e-39 131.0 297K9@1|root,2ZUTC@2|Bacteria,1PBJE@1224|Proteobacteria,1SVP9@1236|Gammaproteobacteria,1XYY8@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF3389) - - - - - - - - - - - - DUF3389 k141_34615_1 483215.BACFIN_05311 1.01e-49 176.0 COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,2FMCJ@200643|Bacteroidia,4AMTX@815|Bacteroidaceae 976|Bacteroidetes T acetoacetate metabolism regulatory protein AtoC K07714 - - - ko:K07713 ko02020,map02020 M00499 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat k141_1255_1 1131730.BAVI_10266 2.32e-51 173.0 2BIXA@1|root,32D5I@2|Bacteria,1TVU8@1239|Firmicutes,4IKV4@91061|Bacilli,1ZHS2@1386|Bacillus 91061|Bacilli S CAAX protease self-immunity - - - - - - - - - - - - Abi k141_18010_1 1120971.AUCA01000056_gene2668 1.15e-27 110.0 COG0214@1|root,COG0214@2|Bacteria,1TPSZ@1239|Firmicutes,4H9RA@91061|Bacilli,2794Y@186823|Alicyclobacillaceae 91061|Bacilli H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively pdxS GO:0003674,GO:0005488,GO:0005515,GO:0042802 4.3.3.6 ko:K06215 ko00750,map00750 - R07456 RC00010,RC01783,RC03043 ko00000,ko00001,ko01000 - - - SOR_SNZ k141_14419_1 1487953.JMKF01000027_gene1497 4.45e-59 199.0 COG1653@1|root,COG1653@2|Bacteria,1G2MI@1117|Cyanobacteria,1H7HU@1150|Oscillatoriales 1117|Cyanobacteria G Carbohydrate ABC transporter substrate-binding protein, CUT1 family srrA - - ko:K17244 ko02010,map02010 M00601 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.40 - - SBP_bac_1,SBP_bac_8 k141_13242_2 1408823.AXUS01000009_gene2004 4.86e-05 51.2 COG2120@1|root,COG2120@2|Bacteria,1VT36@1239|Firmicutes,24XRP@186801|Clostridia,25RK0@186804|Peptostreptococcaceae 186801|Clostridia S GlcNAc-PI de-N-acetylase - - - - - - - - - - - - PIG-L k141_13242_4 1134413.ANNK01000120_gene2048 4.06e-35 127.0 COG2197@1|root,COG2197@2|Bacteria 2|Bacteria K response regulator - - - - - - - - - - - - HNH_3 k141_13242_5 1158607.UAU_00200 0.000895 44.7 COG1476@1|root,COG1476@2|Bacteria,1UWY5@1239|Firmicutes,4I944@91061|Bacilli,4B3Q3@81852|Enterococcaceae 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_3 k141_13242_11 1308866.J416_09559 3.83e-25 96.7 2E7UF@1|root,3329G@2|Bacteria,1VIA6@1239|Firmicutes,4HNNC@91061|Bacilli 91061|Bacilli S Bacteriophage A118-like holin, Hol118 - - - - - - - - - - - - Phage_holin_5_1 k141_13242_12 1348908.KI518589_gene2520 3.59e-41 153.0 COG0860@1|root,COG0860@2|Bacteria,1V3MD@1239|Firmicutes,4HHD1@91061|Bacilli,1ZBPF@1386|Bacillus 91061|Bacilli M n-acetylmuramoyl-L-alanine amidase - - 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - Amidase_3,SH3_3,SLH,SPOR k141_3721_1 1219065.VPR01S_18_00480 1.86e-88 270.0 COG3324@1|root,COG3324@2|Bacteria,1R81W@1224|Proteobacteria,1RYXR@1236|Gammaproteobacteria,1XZ8D@135623|Vibrionales 135623|Vibrionales S Glyoxalase-like domain - - - - - - - - - - - - Glyoxalase k141_3721_2 378806.STAUR_0351 6.34e-07 51.2 COG3865@1|root,COG3865@2|Bacteria,1N7IY@1224|Proteobacteria,42QW0@68525|delta/epsilon subdivisions,2WMZW@28221|Deltaproteobacteria,2YV61@29|Myxococcales 28221|Deltaproteobacteria H 3-demethylubiquinone-9 3-methyltransferase - - 2.1.1.222,2.1.1.64 ko:K00568 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04988,R05614,R08769,R08781 RC00003,RC00392,RC01895 ko00000,ko00001,ko00002,ko01000 - - - 3-dmu-9_3-mt k141_28700_1 1042377.AFPJ01000042_gene1029 2.19e-42 149.0 COG1940@1|root,COG1940@2|Bacteria,1MU94@1224|Proteobacteria,1RQ3P@1236|Gammaproteobacteria,466G9@72275|Alteromonadaceae 1236|Gammaproteobacteria GK ROK family bglK - 2.7.1.2,2.7.1.4,2.7.1.85 ko:K00845,ko:K00847,ko:K18673 ko00010,ko00051,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00051,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R00760,R00867,R01600,R01786,R03920 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - ROK k141_7254_1 314265.R2601_16710 2.61e-82 247.0 COG4764@1|root,COG4764@2|Bacteria,1MVRK@1224|Proteobacteria,2TRJD@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein conserved in bacteria - - - - - - - - - - - - SLT k141_15620_2 1042377.AFPJ01000005_gene2470 8.76e-198 560.0 COG4783@1|root,COG4783@2|Bacteria,1QUMJ@1224|Proteobacteria,1T2RP@1236|Gammaproteobacteria,4660W@72275|Alteromonadaceae 1236|Gammaproteobacteria S Zn-dependent protease, contains TPR repeats - - - - - - - - - - - - Peptidase_M48,TPR_16,TPR_2,TPR_8 k141_15620_4 1279017.AQYJ01000027_gene1869 2.86e-154 436.0 COG3022@1|root,COG3022@2|Bacteria,1MUAF@1224|Proteobacteria,1RMTD@1236|Gammaproteobacteria,4644D@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the UPF0246 family yaaA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0033194,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:1901700 - ko:K09861 - - - - ko00000 - - - H2O2_YaaD k141_15620_5 1279017.AQYJ01000027_gene1870 1.65e-84 256.0 COG0500@1|root,COG0500@2|Bacteria,1RDHE@1224|Proteobacteria,1S3U0@1236|Gammaproteobacteria,46D40@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Protein of unknown function (DUF938) - - - - - - - - - - - - DUF938 k141_32193_1 1158762.KB898066_gene1140 1.04e-32 117.0 COG2963@1|root,COG2963@2|Bacteria,1N1AA@1224|Proteobacteria,1S9QC@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Transposase - - - ko:K07483 - - - - ko00000 - - - HTH_Tnp_1 k141_2528_1 218284.CCDN010000001_gene24 7.93e-146 449.0 COG1196@1|root,COG1196@2|Bacteria,1TPJV@1239|Firmicutes,4HB89@91061|Bacilli,1ZAWM@1386|Bacillus 91061|Bacilli D Required for chromosome condensation and partitioning smc GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K03529 - - - - ko00000,ko03036 - - - SMC_N,SMC_hinge k141_22735_1 218284.CCDN010000002_gene2121 2e-135 396.0 COG0119@1|root,COG0119@2|Bacteria,1TP4Y@1239|Firmicutes,4HA6E@91061|Bacilli,1ZC5T@1386|Bacillus 91061|Bacilli E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) leuA - 2.3.3.13 ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 M00432 R01213 RC00004,RC00470,RC02754 br01601,ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS10690,iYO844.BSU28280 HMGL-like,LeuA_dimer k141_34616_1 566466.NOR53_1143 1.2e-41 157.0 COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,1RPC6@1236|Gammaproteobacteria 1236|Gammaproteobacteria L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA - - 3.6.4.12 ko:K16898 - - - - ko00000,ko01000,ko03400 - - - PDDEXK_1,UvrD-helicase,UvrD_C k141_16763_1 1294265.JCM21738_1290 4.83e-112 323.0 COG0425@1|root,COG0607@1|root,COG0425@2|Bacteria,COG0607@2|Bacteria,1V1GU@1239|Firmicutes,4HFR8@91061|Bacilli,1ZAVN@1386|Bacillus 91061|Bacilli OP Belongs to the sulfur carrier protein TusA family yrkF - - - - - - - - - - - Rhodanese,TusA k141_9630_1 218284.CCDN010000005_gene3321 1.17e-101 297.0 COG1267@1|root,COG1267@2|Bacteria,1V3I0@1239|Firmicutes,4HH4Y@91061|Bacilli,1ZFQE@1386|Bacillus 91061|Bacilli I COG1267 Phosphatidylglycerophosphatase A and related proteins pgpA - - - - - - - - - - - PgpA k141_9630_2 218284.CCDN010000005_gene3320 1.02e-70 218.0 COG2382@1|root,COG2382@2|Bacteria,1UCAC@1239|Firmicutes,4HC02@91061|Bacilli,1ZBAQ@1386|Bacillus 91061|Bacilli P COG2382 Enterochelin esterase and related enzymes yjcH - - ko:K07214 - - - - ko00000 - - - Esterase k141_12009_1 218284.CCDN010000007_gene3816 1.21e-74 235.0 COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,4H9Y8@91061|Bacilli,1ZBUR@1386|Bacillus 91061|Bacilli L Participates in initiation and elongation during chromosome replication dnaB GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k141_7255_1 1453501.JELR01000001_gene2002 4.64e-96 290.0 COG0438@1|root,COG0438@2|Bacteria,1NA28@1224|Proteobacteria,1RQBV@1236|Gammaproteobacteria,4668K@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0438 Glycosyltransferase - - - - - - - - - - - - DUF3524,Glyco_trans_1_4,Glycos_transf_1 k141_14421_1 861299.J421_0897 1.38e-53 183.0 COG0031@1|root,COG0031@2|Bacteria,1ZTA6@142182|Gemmatimonadetes 142182|Gemmatimonadetes EK Domain in cystathionine beta-synthase and other proteins. - - 4.2.1.22 ko:K01697 ko00260,ko00270,ko01100,ko01130,ko01230,map00260,map00270,map01100,map01130,map01230 M00035,M00338 R00891,R01290,R04942 RC00056,RC00069,RC00256,RC00489,RC01246 ko00000,ko00001,ko00002,ko01000 - - - CBS,PALP k141_25065_1 1453501.JELR01000002_gene398 3.34e-66 214.0 COG0845@1|root,COG0845@2|Bacteria,1R4JA@1224|Proteobacteria,1RPS5@1236|Gammaproteobacteria,46CMW@72275|Alteromonadaceae 1236|Gammaproteobacteria M Biotin-lipoyl like - - - ko:K18302,ko:K21136 - M00642,M00821 - - ko00000,ko00002,ko01504,ko02000 2.A.6.2,2.A.6.2.27,8.A.1 - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 k141_15621_1 218284.CCDN010000005_gene3234 1.67e-80 244.0 2EBJR@1|root,335K6@2|Bacteria,1VF1J@1239|Firmicutes,4HNKG@91061|Bacilli,1ZI2K@1386|Bacillus 91061|Bacilli S Spore germination protein gerPC - - ko:K06301 - - - - ko00000 - - - GerPC k141_8479_1 1294265.JCM21738_3348 3.04e-112 338.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,1ZAY7@1386|Bacillus 91061|Bacilli V ABC transporter ygaD GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702 - ko:K11085 ko02010,map02010 - - - ko00000,ko00001,ko01000,ko02000 3.A.1.106 - - ABC_membrane,ABC_tran k141_1257_1 1124991.MU9_2905 9.46e-90 277.0 COG5565@1|root,COG5565@2|Bacteria,1R6R3@1224|Proteobacteria,1RY0J@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Terminase-like family - - - - - - - - - - - - Terminase_6,Terminase_6C k141_18011_3 1121936.AUHI01000006_gene2058 1.69e-35 125.0 COG0494@1|root,COG0494@2|Bacteria,1V4B2@1239|Firmicutes,4HGZZ@91061|Bacilli 91061|Bacilli L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - - - - - - - - - - NUDIX k141_31073_1 1121938.AUDY01000012_gene3642 1.85e-18 81.6 COG1670@1|root,COG1670@2|Bacteria,1V9MA@1239|Firmicutes,4HIFV@91061|Bacilli,3NF18@45667|Halobacillus 91061|Bacilli J Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_3 k141_31073_2 1305836.AXVE01000011_gene1147 9.4e-35 127.0 COG1957@1|root,COG1957@2|Bacteria,1TRWG@1239|Firmicutes,4HCMZ@91061|Bacilli 91061|Bacilli F nucleoside hydrolase rihA_1 - 3.2.2.1 ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 - R01245,R01273,R01677,R01770,R02143 RC00033,RC00063,RC00122,RC00318,RC00485 ko00000,ko00001,ko01000 - - - IU_nuc_hydro k141_34617_1 1279017.AQYJ01000021_gene2905 1.5e-98 300.0 COG0477@1|root,COG2814@2|Bacteria,1RAYJ@1224|Proteobacteria,1S7XJ@1236|Gammaproteobacteria,46AYE@72275|Alteromonadaceae 1236|Gammaproteobacteria EGP Transmembrane secretion effector - - - - - - - - - - - - MFS_1,MFS_3 k141_7256_1 218284.CCDN010000001_gene175 2.17e-103 306.0 COG1131@1|root,COG1131@2|Bacteria,1TQUS@1239|Firmicutes,4IPX9@91061|Bacilli,1ZDPX@1386|Bacillus 91061|Bacilli V ATPases associated with a variety of cellular activities - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 k141_7256_2 218284.CCDN010000001_gene174 1.24e-36 130.0 COG1277@1|root,COG1277@2|Bacteria,1V2H6@1239|Firmicutes,4HC35@91061|Bacilli,1ZDQU@1386|Bacillus 91061|Bacilli S ABC-type transport system involved in multi-copper enzyme maturation, permease component - - - - - - - - - - - - ABC2_membrane_2,ABC2_membrane_3 k141_26316_1 218284.CCDN010000001_gene1094 5.54e-192 538.0 COG0539@1|root,COG0539@2|Bacteria,1TQ9N@1239|Firmicutes,4H9PX@91061|Bacilli,1ZARR@1386|Bacillus 91061|Bacilli J Ribosomal protein S1 rpsA - - ko:K02945 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - S1 k141_26316_2 1121090.KB894692_gene2172 1.07e-25 100.0 COG0204@1|root,COG0204@2|Bacteria,1U8N2@1239|Firmicutes,4HDQR@91061|Bacilli,1ZE5P@1386|Bacillus 91061|Bacilli I 1-acyl-sn-glycerol-3-phosphate acyltransferase plsC - 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase k141_8480_1 882083.SacmaDRAFT_2941 7.72e-37 134.0 COG1319@1|root,COG1319@2|Bacteria,2GT14@201174|Actinobacteria,4E0PT@85010|Pseudonocardiales 201174|Actinobacteria C carbon monoxide dehydrogenase - - 1.2.5.3 ko:K03519 - - R11168 RC02800 ko00000,ko01000 - - - CO_deh_flav_C,FAD_binding_5 k141_29829_2 1116375.VEJY3_13375 8.16e-185 516.0 COG0668@1|root,COG0668@2|Bacteria,1N596@1224|Proteobacteria,1RQZP@1236|Gammaproteobacteria,1XU44@135623|Vibrionales 135623|Vibrionales M COG0668 Small-conductance mechanosensitive channel mscS - - ko:K03442 - - - - ko00000,ko02000 1.A.23.2 - - MS_channel,TM_helix k141_29829_3 1116375.VEJY3_13380 3.24e-249 685.0 COG0191@1|root,COG0191@2|Bacteria,1MURX@1224|Proteobacteria,1RQUC@1236|Gammaproteobacteria,1XUCQ@135623|Vibrionales 135623|Vibrionales G COG0191 Fructose tagatose bisphosphate aldolase fbaA - 4.1.2.13 ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000 - - - F_bP_aldolase k141_29829_4 223926.28807610 2.18e-268 736.0 COG0126@1|root,COG0126@2|Bacteria,1MUNU@1224|Proteobacteria,1RMUQ@1236|Gammaproteobacteria,1XT9V@135623|Vibrionales 135623|Vibrionales F Belongs to the phosphoglycerate kinase family pgk GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.3 ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01512 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGK k141_29829_5 1116375.VEJY3_13390 1.95e-243 669.0 COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,1RMBM@1236|Gammaproteobacteria,1XUQJ@135623|Vibrionales 135623|Vibrionales H Catalyzes the NAD-dependent conversion of D-erythrose 4- phosphate to 4-phosphoerythronate epd GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0048001,GO:0055114 1.2.1.72 ko:K03472 ko00750,ko01100,map00750,map01100 M00124 R01825 RC00242 ko00000,ko00001,ko00002,ko01000 - - - Gp_dh_C,Gp_dh_N k141_29829_7 1219076.N646_3933 8e-200 569.0 COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,1RMWP@1236|Gammaproteobacteria,1XSX1@135623|Vibrionales 135623|Vibrionales G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate tkt - 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C,Transketolase_N k141_12010_1 218284.CCDN010000006_gene3623 4.75e-123 382.0 COG0457@1|root,COG0457@2|Bacteria,1TSH7@1239|Firmicutes,4HACN@91061|Bacilli,1ZBDH@1386|Bacillus 91061|Bacilli M Tetratricopeptide repeat - - - - - - - - - - - - - k141_14423_1 1042377.AFPJ01000024_gene801 9.34e-117 340.0 COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,1RMVK@1236|Gammaproteobacteria,4655B@72275|Alteromonadaceae 1236|Gammaproteobacteria M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins lgt GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009058,GO:0009059,GO:0009898,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0019538,GO:0031224,GO:0031226,GO:0034645,GO:0036211,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0140096,GO:1901564,GO:1901566,GO:1901576 - ko:K13292 - - - - ko00000,ko01000 - - - LGT k141_6119_1 218284.CCDN010000004_gene3043 2.15e-122 352.0 COG1647@1|root,COG1647@2|Bacteria,1TVX4@1239|Firmicutes,4HFF2@91061|Bacilli,1ZD8C@1386|Bacillus 91061|Bacilli S COG1647 Esterase lipase - - 3.1.1.1 ko:K03928 - - - - ko00000,ko01000 - - - Abhydrolase_1,Hydrolase_4 k141_15622_1 1294265.JCM21738_3746 5.08e-90 270.0 COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,4H9R8@91061|Bacilli,1ZBD2@1386|Bacillus 91061|Bacilli P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates ecfA1 - - ko:K16786 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran k141_15622_2 1294265.JCM21738_3747 2.5e-92 276.0 COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,4HA7T@91061|Bacilli,1ZBBK@1386|Bacillus 91061|Bacilli P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates ecfA2 GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0008150,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085 - ko:K16787 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran k141_28701_1 1123257.AUFV01000005_gene1283 3.57e-36 138.0 COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,1RPNE@1236|Gammaproteobacteria,1X5B0@135614|Xanthomonadales 135614|Xanthomonadales I AMP-binding enzyme - - - - - - - - - - - - AMP-binding k141_26317_1 929704.Myrod_2409 3.26e-15 73.9 COG1670@1|root,COG1670@2|Bacteria,4NM3W@976|Bacteroidetes,1I1E4@117743|Flavobacteriia 976|Bacteroidetes J Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_3 k141_27439_2 1116375.VEJY3_05355 1.19e-121 347.0 COG1396@1|root,COG1917@1|root,COG1396@2|Bacteria,COG1917@2|Bacteria,1R4NU@1224|Proteobacteria,1RQG0@1236|Gammaproteobacteria,1XUWN@135623|Vibrionales 135623|Vibrionales K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - Cupin_2,HTH_3 k141_27439_3 491952.Mar181_2516 7.42e-165 469.0 COG0715@1|root,COG0715@2|Bacteria,1MVJA@1224|Proteobacteria,1RWXD@1236|Gammaproteobacteria,1XQ7M@135619|Oceanospirillales 135619|Oceanospirillales P NMT1-like family - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - - k141_27439_4 491952.Mar181_2517 1.37e-35 129.0 COG0600@1|root,COG0600@2|Bacteria,1MWDJ@1224|Proteobacteria,1RQ0A@1236|Gammaproteobacteria,1XJ84@135619|Oceanospirillales 135619|Oceanospirillales P Binding-protein-dependent transport system inner membrane component - - - ko:K02050 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - BPD_transp_1 k141_23874_1 1298593.TOL_1373 1.44e-129 377.0 COG0027@1|root,COG0027@2|Bacteria,1N3KA@1224|Proteobacteria,1RNTW@1236|Gammaproteobacteria,1XHPS@135619|Oceanospirillales 135619|Oceanospirillales F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate purT - 2.1.2.2 ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04325,R04326 RC00026,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp,Epimerase k141_23874_2 1038860.AXAP01000101_gene5275 7.31e-109 332.0 COG5361@1|root,COG5361@2|Bacteria,1NX2A@1224|Proteobacteria,2TTBA@28211|Alphaproteobacteria,3JX1U@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF1214) - - - - - - - - - - - - DUF1214,DUF1254 k141_18012_1 644107.SL1157_A0268 1.11e-95 297.0 COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,2TXAW@28211|Alphaproteobacteria,4NBEB@97050|Ruegeria 28211|Alphaproteobacteria S hmm pf01979 - - - - - - - - - - - - Amidohydro_3 k141_32194_1 218284.CCDN010000005_gene3214 2.82e-176 499.0 COG0501@1|root,COG0501@2|Bacteria,1TRQE@1239|Firmicutes,4HD5G@91061|Bacilli,1ZC4F@1386|Bacillus 91061|Bacilli O Peptidase M48 yhfN GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0070011,GO:0071586,GO:0071704,GO:0080120,GO:0140096,GO:1901564 - - - - - - - - - - Peptidase_M48,Peptidase_M48_N k141_1259_1 1294265.JCM21738_4116 1.67e-143 412.0 COG2223@1|root,COG2223@2|Bacteria,1TRS9@1239|Firmicutes,4HEBM@91061|Bacilli,1ZQ92@1386|Bacillus 91061|Bacilli P nitrite transporter narK - - ko:K02575 ko00910,map00910 M00615 - - ko00000,ko00001,ko00002,ko02000 2.A.1.8 - - MFS_1 k141_6120_1 1408303.JNJJ01000020_gene4077 3.87e-29 110.0 COG1131@1|root,COG1131@2|Bacteria,1TQIH@1239|Firmicutes,4HA2B@91061|Bacilli,1ZBAI@1386|Bacillus 91061|Bacilli V transporter (ATP-binding protein) ecsA - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_6160_1 1328313.DS2_03410 6.57e-54 183.0 COG0477@1|root,COG2814@2|Bacteria,1MVKJ@1224|Proteobacteria,1RMHJ@1236|Gammaproteobacteria,464EA@72275|Alteromonadaceae 1236|Gammaproteobacteria EGP Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family xylE GO:0003674,GO:0005215,GO:0005351,GO:0005402,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0008643,GO:0015075,GO:0015077,GO:0015078,GO:0015144,GO:0015145,GO:0015146,GO:0015148,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015519,GO:0015672,GO:0015749,GO:0015750,GO:0015753,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034219,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 - ko:K05548,ko:K08138,ko:K08139 ko04113,map04113 - - - ko00000,ko00001,ko02000 2.A.1.1,2.A.1.1.3,2.A.1.15 - iECIAI1_1343.ECIAI1_4259,iECSE_1348.ECSE_4322 Sugar_tr k141_6160_2 498211.CJA_3064 7.13e-33 125.0 COG0477@1|root,COG2814@2|Bacteria,1MVKJ@1224|Proteobacteria,1RMHJ@1236|Gammaproteobacteria,1FGFP@10|Cellvibrio 1236|Gammaproteobacteria U Sugar (and other) transporter xylE GO:0003674,GO:0005215,GO:0005351,GO:0005402,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0008643,GO:0015075,GO:0015077,GO:0015078,GO:0015144,GO:0015145,GO:0015146,GO:0015148,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015519,GO:0015672,GO:0015749,GO:0015750,GO:0015753,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034219,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 - ko:K05548,ko:K08138,ko:K08139 ko04113,map04113 - - - ko00000,ko00001,ko02000 2.A.1.1,2.A.1.1.3,2.A.1.15 - iECIAI1_1343.ECIAI1_4259,iECSE_1348.ECSE_4322 Sugar_tr k141_14444_1 1385513.N780_17480 4.51e-35 123.0 COG0225@1|root,COG0225@2|Bacteria,1V4HF@1239|Firmicutes,4HHQM@91061|Bacilli,2YAC5@289201|Pontibacillus 91061|Bacilli O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine msrA - 1.8.4.11 ko:K07304 - - - - ko00000,ko01000 - - - PMSR k141_7288_1 309807.SRU_0982 7.59e-06 47.4 COG5505@1|root,COG5505@2|Bacteria,4NE2H@976|Bacteroidetes,1FJQG@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes S Protein of unknown function (DUF819) - - - - - - - - - - - - DUF819 k141_7288_2 194439.CT0358 2.71e-30 118.0 COG0158@1|root,COG0158@2|Bacteria,1FDR7@1090|Chlorobi 1090|Chlorobi F D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 fbp - 3.1.3.11 ko:K03841 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910 M00003,M00165,M00167,M00344 R00762,R04780 RC00017 ko00000,ko00001,ko00002,ko01000,ko04147 - - - FBPase k141_28734_1 218284.CCDN010000001_gene1512 7.17e-47 160.0 COG0709@1|root,COG0709@2|Bacteria,1TQCJ@1239|Firmicutes,4HB6P@91061|Bacilli,1ZCAH@1386|Bacillus 91061|Bacilli E Synthesizes selenophosphate from selenide and ATP selD - 2.7.9.3 ko:K01008 ko00450,ko01100,map00450,map01100 - R03595 RC00002,RC02878 ko00000,ko00001,ko01000,ko03016 - - - AIRS,AIRS_C k141_28734_2 1243664.CAVL020000025_gene1296 4.36e-27 106.0 COG0709@1|root,COG0709@2|Bacteria,1TQCJ@1239|Firmicutes,4HB6P@91061|Bacilli,1ZCAH@1386|Bacillus 91061|Bacilli E Synthesizes selenophosphate from selenide and ATP selD - 2.7.9.3 ko:K01008 ko00450,ko01100,map00450,map01100 - R03595 RC00002,RC02878 ko00000,ko00001,ko01000,ko03016 - - - AIRS,AIRS_C k141_1294_1 315750.BPUM_0602 1.85e-66 223.0 COG0046@1|root,COG0046@2|Bacteria,1TPAS@1239|Firmicutes,4HB3N@91061|Bacilli,1ZCN8@1386|Bacillus 91061|Bacilli F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL purL GO:0000166,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C k141_19149_1 247639.MGP2080_06897 5.73e-71 232.0 COG0591@1|root,COG0591@2|Bacteria,1R86J@1224|Proteobacteria,1S1QC@1236|Gammaproteobacteria,1J9SH@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - - - - - - - - - - SSF k141_16797_1 1294265.JCM21738_3244 1.25e-117 346.0 COG0104@1|root,COG0104@2|Bacteria,1TQ4C@1239|Firmicutes,4H9YT@91061|Bacilli,1ZBF8@1386|Bacillus 91061|Bacilli F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP purA GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 - - - Adenylsucc_synt k141_24049_2 648996.Theam_0490 5.67e-11 64.3 COG0639@1|root,COG0639@2|Bacteria,2G41R@200783|Aquificae 200783|Aquificae T Calcineurin-like phosphoesterase superfamily domain - - - - - - - - - - - - Metallophos_2 k141_33566_2 640512.BC1003_4061 1.02e-18 90.5 COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,2VKMH@28216|Betaproteobacteria,1K14G@119060|Burkholderiaceae 28216|Betaproteobacteria M PFAM glycosyl transferase family 9 - - - - - - - - - - - - Glyco_transf_9 k141_3927_1 218284.CCDN010000002_gene2397 4.11e-83 247.0 COG3238@1|root,COG3238@2|Bacteria,1V6JX@1239|Firmicutes,4HJKC@91061|Bacilli,1ZR02@1386|Bacillus 91061|Bacilli S Putative inner membrane exporter, YdcZ - - - ko:K09936 ko02024,map02024 - - - ko00000,ko00001,ko02000 2.A.7.21 - - DMT_YdcZ k141_27565_1 500635.MITSMUL_05624 6.98e-28 117.0 COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,4H207@909932|Negativicutes 909932|Negativicutes M Penicillin-binding protein, transpeptidase domain protein ftsI - 3.4.16.4 ko:K03587,ko:K08384 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011,ko03036 - - - PASTA,PBP_dimer,Transpeptidase k141_392_2 441769.ABFU01000028_gene1417 6.85e-33 124.0 COG1317@1|root,COG1317@2|Bacteria,1VEUV@1239|Firmicutes,4HG3R@91061|Bacilli,1ZE47@1386|Bacillus 91061|Bacilli NU COG1317 Flagellar biosynthesis type III secretory pathway protein fliH - - ko:K02411 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - FliH k141_392_3 218284.CCDN010000001_gene1931 1.76e-95 286.0 COG1536@1|root,COG1536@2|Bacteria,1TP01@1239|Firmicutes,4HAFZ@91061|Bacilli,1ZAQU@1386|Bacillus 91061|Bacilli N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation fliG - - ko:K02410 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02035 - - - FliG_C,FliG_M,FliG_N k141_12273_1 1116375.VEJY3_13235 1.29e-204 574.0 COG2265@1|root,COG2265@2|Bacteria,1MV3A@1224|Proteobacteria,1RN1D@1236|Gammaproteobacteria,1XUN9@135623|Vibrionales 135623|Vibrionales J Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA rlmD GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.190 ko:K03215 - - - - ko00000,ko01000,ko03009 - - - TRAM,tRNA_U5-meth_tr k141_12273_2 1116375.VEJY3_13230 0.0 1426.0 COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,1RN3H@1236|Gammaproteobacteria,1XTUV@135623|Vibrionales 135623|Vibrionales KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance relA - 2.7.6.5 ko:K00951 ko00230,map00230 - R00429 RC00002,RC00078 ko00000,ko00001,ko01000 - - - ACT_4,HD_4,RelA_SpoT,TGS k141_12273_3 945550.VISI1226_09079 3.49e-26 103.0 COG1694@1|root,COG3956@2|Bacteria,1MVKM@1224|Proteobacteria,1RNVU@1236|Gammaproteobacteria,1XVCP@135623|Vibrionales 135623|Vibrionales S Nucleoside triphosphate mazG - 3.6.1.9 ko:K04765 ko00230,ko00240,ko00760,ko00770,ko01100,map00230,map00240,map00760,map00770,map01100 - R00086,R00087,R00103,R00287,R00426,R00515,R00662,R00720,R03004,R03036,R11323 RC00002 ko00000,ko00001,ko01000 - - - MazG k141_13420_1 1280001.BAOA01000243_gene4579 1.38e-63 194.0 COG0596@1|root,COG0596@2|Bacteria,1QVBQ@1224|Proteobacteria,1T2BH@1236|Gammaproteobacteria,1Y3C9@135623|Vibrionales 135623|Vibrionales S Alpha beta hydrolase - - - - - - - - - - - - - k141_13420_2 357809.Cphy_2165 2.5e-83 249.0 28NW8@1|root,33QYW@2|Bacteria,1UPPN@1239|Firmicutes,25HKN@186801|Clostridia 186801|Clostridia S Pfam:Pyridox_oxidase - - - - - - - - - - - - Putative_PNPOx k141_13420_4 1187848.AJYQ01000151_gene2453 2.54e-182 511.0 COG0583@1|root,COG0583@2|Bacteria,1MU7H@1224|Proteobacteria,1RPF8@1236|Gammaproteobacteria,1XUI7@135623|Vibrionales 135623|Vibrionales K Bacterial regulatory helix-turn-helix protein, lysR family - - - - - - - - - - - - HTH_1,LysR_substrate k141_13420_5 1537994.JQFW01000057_gene608 1.74e-20 89.7 COG0477@1|root,COG2814@2|Bacteria,1MU9G@1224|Proteobacteria,1RM9G@1236|Gammaproteobacteria,4664V@72275|Alteromonadaceae 1236|Gammaproteobacteria EGP Arabinose efflux permease ydhP - - ko:K18567,ko:K19577 - - - - ko00000,ko02000 2.A.1.2.25,2.A.1.2.65 - - MFS_1,Sugar_tr k141_28887_1 1082933.MEA186_17129 8.94e-100 303.0 COG1015@1|root,COG1015@2|Bacteria,1MVN8@1224|Proteobacteria,2TRMP@28211|Alphaproteobacteria,43H19@69277|Phyllobacteriaceae 28211|Alphaproteobacteria G Phosphotransfer between the C1 and C5 carbon atoms of pentose deoB - 5.4.2.7 ko:K01839 ko00030,ko00230,map00030,map00230 - R01057,R02749 RC00408 ko00000,ko00001,ko01000 - - - Metalloenzyme k141_9777_1 1116375.VEJY3_21971 1.17e-93 288.0 COG1109@1|root,COG1109@2|Bacteria,1QUGD@1224|Proteobacteria,1RQME@1236|Gammaproteobacteria,1XVES@135623|Vibrionales 135623|Vibrionales G Phosphoglucomutase phosphomannomutase alpha beta subunit - - 5.4.2.8 ko:K01840 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 M00114 R01818 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV k141_9777_2 1116375.VEJY3_21966 1.31e-265 729.0 COG1622@1|root,COG1622@2|Bacteria,1MWHZ@1224|Proteobacteria,1RP4H@1236|Gammaproteobacteria,1XSF8@135623|Vibrionales 135623|Vibrionales C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) coxB - 1.9.3.1 ko:K02275 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.4,3.D.4.6 - - COX2,COX2_TM,Cytochrome_CBB3 k141_9777_3 1116375.VEJY3_21961 0.0 1090.0 COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,1RPC3@1236|Gammaproteobacteria,1XU9F@135623|Vibrionales 135623|Vibrionales C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B coxA - 1.9.3.1 ko:K02274 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6 - - COX1 k141_9777_4 1116375.VEJY3_21956 8.08e-76 229.0 COG3175@1|root,COG3175@2|Bacteria,1RDTU@1224|Proteobacteria,1S5XA@1236|Gammaproteobacteria,1XVB6@135623|Vibrionales 135623|Vibrionales O COG3175 Cytochrome oxidase assembly factor coxG - - ko:K02258 ko00190,ko01100,ko04714,map00190,map01100,map04714 M00154 - - ko00000,ko00001,ko00002,ko03029 3.D.4.8 - - CtaG_Cox11 k141_2703_1 471223.GWCH70_0849 2.37e-165 472.0 COG0436@1|root,COG0436@2|Bacteria,1TQD6@1239|Firmicutes,4HAHQ@91061|Bacilli,1WEAE@129337|Geobacillus 91061|Bacilli E Aminotransferase class I and II mtnE - - ko:K08969 ko00270,ko01100,map00270,map01100 M00034 R07396 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k141_33599_2 1279017.AQYJ01000027_gene1754 3.24e-238 659.0 COG1622@1|root,COG1622@2|Bacteria,1MWHZ@1224|Proteobacteria,1RP4H@1236|Gammaproteobacteria,465CG@72275|Alteromonadaceae 1236|Gammaproteobacteria C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) coxB - 1.9.3.1 ko:K02275 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.4,3.D.4.6 - - COX2,COX2_TM,Cytochrome_CBB3 k141_33599_3 1279017.AQYJ01000027_gene1755 3.47e-215 606.0 COG0534@1|root,COG0534@2|Bacteria,1MV6B@1224|Proteobacteria,1RPGF@1236|Gammaproteobacteria,46598@72275|Alteromonadaceae 1236|Gammaproteobacteria V COG0534 Na -driven multidrug efflux pump dinF - - ko:K03327 - - - - ko00000,ko02000 2.A.66.1 - - MatE k141_22943_2 257313.BP0206 3.46e-16 79.0 COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,2VHS3@28216|Betaproteobacteria,3T1EM@506|Alcaligenaceae 28216|Betaproteobacteria H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction thiC - 4.1.99.17 ko:K03147 ko00730,ko01100,map00730,map01100 M00127 R03472 RC03251,RC03252 ko00000,ko00001,ko00002,ko01000 - - - ThiC-associated,ThiC_Rad_SAM k141_2727_1 1238450.VIBNISOn1_1720070 6.16e-71 225.0 COG1879@1|root,COG1879@2|Bacteria,1MVDG@1224|Proteobacteria,1RMBR@1236|Gammaproteobacteria,1XTNH@135623|Vibrionales 135623|Vibrionales G Periplasmic binding protein domain - - - ko:K10537 ko02010,map02010 M00213 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.2 - - Peripla_BP_1 k141_419_2 349521.HCH_01199 4.04e-21 111.0 COG1388@1|root,COG3209@1|root,COG1388@2|Bacteria,COG3209@2|Bacteria,1R5VC@1224|Proteobacteria,1RR29@1236|Gammaproteobacteria 1236|Gammaproteobacteria M RHS Repeat - - - - - - - - - - - - He_PIG,LysM,RHS_repeat k141_9823_1 1122137.AQXF01000004_gene1857 1.08e-26 113.0 COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,2U099@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Sulfotransferase domain - - - - - - - - - - - - Sulfotransfer_3,TPR_16,TPR_2,TPR_8 k141_3971_1 390989.JOEG01000014_gene3114 9.34e-70 226.0 COG1757@1|root,COG1757@2|Bacteria,2I8CQ@201174|Actinobacteria,4D96Q@85008|Micromonosporales 201174|Actinobacteria C Na+/H+ antiporter family nhaC - - ko:K03315 - - - - ko00000,ko02000 2.A.35 - - Na_H_antiporter k141_26646_2 218284.CCDN010000003_gene3003 1.18e-120 345.0 COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,4HFZ2@91061|Bacilli,1ZB7B@1386|Bacillus 91061|Bacilli F Belongs to the purine pyrimidine phosphoribosyltransferase family hpt GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.8,6.3.4.19 ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 - R00190,R01132,R01229,R02142,R08237,R08238,R08245 RC00063,RC00122 ko00000,ko00001,ko01000,ko03016 - - - Pribosyltran k141_26646_3 218284.CCDN010000003_gene3002 1.36e-236 662.0 COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,4H9ZM@91061|Bacilli,1ZBFQ@1386|Bacillus 91061|Bacilli D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine tilS - 2.4.2.8,6.3.4.19 ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 - R01132,R01229,R02142,R09597 RC00063,RC00122,RC02633,RC02634 ko00000,ko00001,ko01000,ko03016 - - - ATP_bind_3,TilS,TilS_C k141_26646_4 218284.CCDN010000003_gene3001 4.02e-34 127.0 COG0515@1|root,COG0515@2|Bacteria,1TSNS@1239|Firmicutes,4HBDI@91061|Bacilli,1ZBVA@1386|Bacillus 91061|Bacilli KLT serine threonine protein kinase yabT - 2.7.11.1 ko:K08884 - - - - ko00000,ko01000,ko01001 - - - Pkinase k141_27583_1 218284.CCDN010000006_gene3680 2.73e-82 251.0 COG2177@1|root,COG2177@2|Bacteria,1TPND@1239|Firmicutes,4HA5A@91061|Bacilli,1ZC4Q@1386|Bacillus 91061|Bacilli D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation ftsX GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0007154,GO:0007165,GO:0007166,GO:0008150,GO:0008356,GO:0009966,GO:0009987,GO:0010033,GO:0010646,GO:0016020,GO:0016043,GO:0019221,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0023052,GO:0032506,GO:0034097,GO:0042173,GO:0042221,GO:0043937,GO:0043938,GO:0044085,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051301,GO:0051716,GO:0065007,GO:0070098,GO:0070297,GO:0070887,GO:0071310,GO:0071345,GO:0071840,GO:0071944,GO:0090529,GO:1902531 - ko:K09811 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - FtsX k141_27583_2 935836.JAEL01000094_gene3368 2.1e-54 175.0 COG2884@1|root,COG2884@2|Bacteria,1TP58@1239|Firmicutes,4H9Z2@91061|Bacilli,1ZCAE@1386|Bacillus 91061|Bacilli D cell division ATP-binding protein FtsE ftsE GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0008356,GO:0009966,GO:0009987,GO:0010646,GO:0016020,GO:0016043,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0032506,GO:0042173,GO:0043937,GO:0043938,GO:0044085,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0051301,GO:0065007,GO:0070297,GO:0071840,GO:0071944,GO:0090529,GO:1902531 - ko:K09812 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - ABC_tran k141_5073_1 218284.CCDN010000001_gene1798 2.73e-125 368.0 COG2262@1|root,COG2262@2|Bacteria,1TNZB@1239|Firmicutes,4HACA@91061|Bacilli,1ZBT6@1386|Bacillus 91061|Bacilli S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis hflX - - ko:K03665 - - - - ko00000,ko03009 - - - GTP-bdg_M,GTP-bdg_N,MMR_HSR1 k141_24075_1 218284.CCDN010000001_gene961 6.56e-65 203.0 COG0511@1|root,COG0511@2|Bacteria,1VAB7@1239|Firmicutes,4HKCS@91061|Bacilli,1ZGFF@1386|Bacillus 91061|Bacilli I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA accB - - ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742 RC00040,RC00367 ko00000,ko00001,ko00002 - - - Biotin_lipoyl k141_22945_2 1453501.JELR01000005_gene1588 8.93e-18 80.1 COG0589@1|root,COG0589@2|Bacteria,1MVZS@1224|Proteobacteria,1RPAE@1236|Gammaproteobacteria,46557@72275|Alteromonadaceae 1236|Gammaproteobacteria T Universal stress protein - - - ko:K14055 - - - - ko00000 - - - Usp k141_12312_2 218284.CCDN010000001_gene1100 1.08e-33 116.0 2E5GX@1|root,3308G@2|Bacteria,1VGKE@1239|Firmicutes,4HPSE@91061|Bacilli,1ZIU7@1386|Bacillus 91061|Bacilli - - ypzH - - - - - - - - - - - - k141_12312_3 218284.CCDN010000001_gene1099 3.66e-13 68.2 28IBV@1|root,2Z8EA@2|Bacteria,1TPCJ@1239|Firmicutes,4HB3C@91061|Bacilli,1ZBT4@1386|Bacillus 91061|Bacilli S YIEGIA protein yphB - - ko:K05739 - - - - ko00000 - - - YIEGIA k141_32335_1 1380358.JADJ01000005_gene2717 6.63e-181 510.0 COG3673@1|root,COG3673@2|Bacteria,1NFRW@1224|Proteobacteria,1RP20@1236|Gammaproteobacteria,1XJNN@135619|Oceanospirillales 135619|Oceanospirillales S Uncharacterized alpha/beta hydrolase domain (DUF2235) - - - - - - - - - - - - DUF2235 k141_32335_2 1042377.AFPJ01000007_gene1864 2.18e-28 110.0 COG0665@1|root,COG0665@2|Bacteria,1RH7N@1224|Proteobacteria,1S9ZE@1236|Gammaproteobacteria,467V9@72275|Alteromonadaceae 1236|Gammaproteobacteria E tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity - - - - - - - - - - - - - k141_3972_1 1453501.JELR01000002_gene495 5.22e-114 336.0 COG0457@1|root,COG0457@2|Bacteria,1PNM7@1224|Proteobacteria,1RXYT@1236|Gammaproteobacteria,46D2N@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0457 FOG TPR repeat - - - - - - - - - - - - Alkyl_sulf_dimr,TPR_19,TPR_8 k141_11001_1 1121121.KB894308_gene160 2.5e-20 88.2 COG1443@1|root,COG1443@2|Bacteria,1V6SB@1239|Firmicutes,4HJ2T@91061|Bacilli,26XCW@186822|Paenibacillaceae 91061|Bacilli I Nudix hydrolase M1-740 - - - - - - - - - - - NUDIX k141_29956_1 1116375.VEJY3_00585 0.0 962.0 COG2911@1|root,COG2911@2|Bacteria,1QUFI@1224|Proteobacteria,1T1X6@1236|Gammaproteobacteria,1XU6R@135623|Vibrionales 135623|Vibrionales S AsmA family - - - - - - - - - - - - AsmA k141_29956_2 223926.28805111 0.0 1044.0 COG1866@1|root,COG1866@2|Bacteria,1MWXN@1224|Proteobacteria,1RPM0@1236|Gammaproteobacteria,1XT8R@135623|Vibrionales 135623|Vibrionales F Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA pckA GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 4.1.1.49 ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 M00003,M00170 R00341 RC00002,RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPCK_ATP k141_29956_3 1116375.VEJY3_00595 9.38e-197 546.0 COG1281@1|root,COG1281@2|Bacteria,1MUMU@1224|Proteobacteria,1RMP3@1236|Gammaproteobacteria,1XTZA@135623|Vibrionales 135623|Vibrionales O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress hslO - - ko:K04083 - - - - ko00000,ko03110 - - - HSP33 k141_29956_4 223926.28805113 1.76e-80 239.0 COG1188@1|root,COG1188@2|Bacteria,1MZR6@1224|Proteobacteria,1S8VU@1236|Gammaproteobacteria,1XXB2@135623|Vibrionales 135623|Vibrionales J implicated in the recycling of the hslR - - ko:K04762 - - - - ko00000,ko03110 - - - S4 k141_29956_5 1116375.VEJY3_00605 7.84e-98 292.0 COG3031@1|root,COG3031@2|Bacteria,1RD3I@1224|Proteobacteria,1RQKA@1236|Gammaproteobacteria,1XU1I@135623|Vibrionales 135623|Vibrionales U general secretion pathway protein epsC GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - ko:K02452 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSC k141_8648_2 223926.28806428 1.58e-36 123.0 2AVYP@1|root,31MSV@2|Bacteria,1QJJ4@1224|Proteobacteria,1THJE@1236|Gammaproteobacteria,1Y19B@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_8648_3 223926.28806427 5.15e-150 424.0 COG2818@1|root,COG2818@2|Bacteria,1R3WB@1224|Proteobacteria,1RSAH@1236|Gammaproteobacteria,1XSJ8@135623|Vibrionales 135623|Vibrionales L 3-methyladenine DNA glycosylase - - - - - - - - - - - - Adenine_glyco k141_8648_4 1116375.VEJY3_06955 0.0 1074.0 COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria,1XVT6@135623|Vibrionales 135623|Vibrionales V ABC transporter transmembrane region - - - ko:K18889 ko02010,map02010 M00707 - - ko00000,ko00001,ko00002,ko02000 3.A.1.106.13,3.A.1.106.5 - - ABC_membrane,ABC_tran k141_8648_5 1116375.VEJY3_06950 0.0 975.0 COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria,1XSQY@135623|Vibrionales 135623|Vibrionales V ABC transporter transmembrane region - - - ko:K18890 ko02010,map02010 M00707 - - ko00000,ko00001,ko00002,ko02000 3.A.1.106.13,3.A.1.106.5 - - ABC_membrane,ABC_tran k141_13470_1 768671.ThimaDRAFT_3169 1.13e-32 119.0 2ESM0@1|root,33K5K@2|Bacteria,1N02H@1224|Proteobacteria,1SA2K@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_13470_2 1187851.A33M_1286 1.87e-32 115.0 COG3293@1|root,COG3293@2|Bacteria,1RDDI@1224|Proteobacteria,2UAE0@28211|Alphaproteobacteria,3FEDB@34008|Rhodovulum 28211|Alphaproteobacteria L Putative transposase of IS4/5 family (DUF4096) - - - ko:K07492 - - - - ko00000 - - - DUF4096 k141_15800_1 491915.Aflv_1921 2.52e-102 327.0 COG0745@1|root,COG5000@1|root,COG5002@1|root,COG0745@2|Bacteria,COG5000@2|Bacteria,COG5002@2|Bacteria,1U7NI@1239|Firmicutes,4HA3E@91061|Bacilli,21W0U@150247|Anoxybacillus 91061|Bacilli T PAS fold - - - - - - - - - - - - GAF,GAF_3,HAMP,HATPase_c,HisKA,Response_reg k141_3974_1 322710.Avin_07810 5.29e-42 153.0 COG2252@1|root,COG2252@2|Bacteria,1MUV0@1224|Proteobacteria,1RMBE@1236|Gammaproteobacteria 1236|Gammaproteobacteria S permease purP - - ko:K06901 - - - - ko00000,ko02000 2.A.1.40 - - Xan_ur_permease k141_18224_1 861299.J421_3934 5.76e-90 276.0 COG1960@1|root,COG1960@2|Bacteria,1ZSVE@142182|Gemmatimonadetes 142182|Gemmatimonadetes I Acyl-CoA dehydrogenase, C-terminal domain - - 1.3.8.6 ko:K00252 ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130 M00032 R02487,R02488,R10074 RC00052,RC00156 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_20464_1 1042377.AFPJ01000053_gene1502 7.78e-88 273.0 COG0651@1|root,COG0651@2|Bacteria,1MURB@1224|Proteobacteria,1RQBG@1236|Gammaproteobacteria,465QH@72275|Alteromonadaceae 1236|Gammaproteobacteria CP COG0651 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit mnhD - - ko:K05568 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - Proton_antipo_M k141_20464_3 1042377.AFPJ01000053_gene1504 4.58e-51 166.0 COG2111@1|root,COG2111@2|Bacteria,1REGG@1224|Proteobacteria 1224|Proteobacteria P Na H antiporter, MnhB mnhB - - ko:K05566 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - MnhB k141_20464_4 1042377.AFPJ01000053_gene1505 1.03e-26 110.0 COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,1RNKN@1236|Gammaproteobacteria,463YS@72275|Alteromonadaceae 1236|Gammaproteobacteria CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit mnhA - - ko:K05565 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - DUF4040,MnhB,Proton_antipo_M,Proton_antipo_N k141_5076_1 1453501.JELR01000002_gene1513 2.13e-89 275.0 COG1273@1|root,COG1273@2|Bacteria,1MWCU@1224|Proteobacteria,1RYQ0@1236|Gammaproteobacteria,46705@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF3426) - - - - - - - - - - - - DUF3426,zinc_ribbon_4,zinc_ribbon_5 k141_35937_1 218284.CCDN010000007_gene3975 6.66e-135 383.0 COG1435@1|root,COG1435@2|Bacteria,1TRVM@1239|Firmicutes,4HA4A@91061|Bacilli,1ZBMX@1386|Bacillus 91061|Bacilli F thymidine kinase tdk GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R01567,R02099,R08233 RC00002,RC00017 ko00000,ko00001,ko01000 - - iYO844.BSU37060 TK k141_35937_2 218284.CCDN010000007_gene3978 1.05e-50 165.0 2F411@1|root,33WSR@2|Bacteria,1VVIK@1239|Firmicutes,4HW8P@91061|Bacilli,1ZGVA@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_34793_1 1279017.AQYJ01000029_gene3376 3.8e-58 184.0 COG0526@1|root,COG0526@2|Bacteria,1RI3N@1224|Proteobacteria,1S5YV@1236|Gammaproteobacteria,466IK@72275|Alteromonadaceae 1236|Gammaproteobacteria CO Thiol disulfide interchange protein dsbE GO:0003674,GO:0003756,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015036,GO:0016020,GO:0016043,GO:0016491,GO:0016667,GO:0016853,GO:0016860,GO:0016864,GO:0017004,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0055114,GO:0065003,GO:0071840,GO:0071944,GO:0098552,GO:0098567,GO:0140096 - ko:K02199 - - - - ko00000,ko03110 - - - Redoxin k141_34793_2 1279017.AQYJ01000029_gene3375 0.0 901.0 COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,1RMY5@1236|Gammaproteobacteria,4649T@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG1138 Cytochrome c biogenesis factor ccmF GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0019538,GO:0020037,GO:0022607,GO:0031224,GO:0031226,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046906,GO:0048037,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564 - ko:K02198 - - - - ko00000,ko02000 9.B.14.1 - - CcmF_C,Cytochrom_C_asm k141_11004_2 218284.CCDN010000001_gene631 1.06e-68 215.0 COG1994@1|root,COG1994@2|Bacteria,1V72P@1239|Firmicutes,4HJFP@91061|Bacilli,1ZQIE@1386|Bacillus 91061|Bacilli S Peptidase family M50 spoIVFB - - ko:K06402 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M50,Peptidase_M50B k141_6389_1 1294265.JCM21738_2260 9.69e-20 89.7 COG1597@1|root,COG1597@2|Bacteria,1TUH3@1239|Firmicutes,4IR1U@91061|Bacilli,1ZRQM@1386|Bacillus 91061|Bacilli I Diacylglycerol kinase catalytic domain ytlR - - - - - - - - - - - DAGK_acc,DAGK_cat k141_6389_2 218284.CCDN010000008_gene4197 4.91e-117 345.0 28NSI@1|root,2ZB4U@2|Bacteria,1UZ00@1239|Firmicutes,4HDBT@91061|Bacilli,1ZDNP@1386|Bacillus 91061|Bacilli - - ytlQ - - - - - - - - - - - NERD k141_19325_1 411684.HPDFL43_00027750 2.52e-128 369.0 COG2801@1|root,COG2801@2|Bacteria,1MVN5@1224|Proteobacteria,2TQK0@28211|Alphaproteobacteria,43IUV@69277|Phyllobacteriaceae 28211|Alphaproteobacteria L Integrase core domain - - - - - - - - - - - - HTH_21,rve,rve_3 k141_32336_1 1116375.VEJY3_13580 1.64e-296 830.0 COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,1RNEB@1236|Gammaproteobacteria,1XTVJ@135623|Vibrionales 135623|Vibrionales J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner valS GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 k141_20465_1 1453501.JELR01000001_gene1831 4.74e-94 283.0 COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,1RNB6@1236|Gammaproteobacteria,464UG@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate usg GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC k141_29957_1 218284.CCDN010000002_gene2035 6.65e-198 552.0 COG1984@1|root,COG1984@2|Bacteria,1TR6U@1239|Firmicutes,4HACC@91061|Bacilli,1ZCFE@1386|Bacillus 91061|Bacilli E Allophanate hydrolase subunit 2 kipA - - ko:K06350 - - - - ko00000 - - - CT_A_B k141_27586_1 1117108.PAALTS15_24305 3.93e-32 122.0 COG5522@1|root,COG5522@2|Bacteria,1V4XE@1239|Firmicutes,4HHC6@91061|Bacilli,26SXX@186822|Paenibacillaceae 91061|Bacilli S integral membrane protein ywaF - - - - - - - - - - - Intg_mem_TP0381 k141_5077_1 877424.ATWC01000004_gene564 1.74e-22 101.0 COG4640@1|root,COG4640@2|Bacteria,1TQ9M@1239|Firmicutes,24DDM@186801|Clostridia,27IWY@186928|unclassified Lachnospiraceae 186801|Clostridia S DUF3160 - - - - - - - - - - - - DUF3160,zinc_ribbon_2 k141_15801_1 218284.CCDN010000001_gene1675 2.76e-101 308.0 COG3048@1|root,COG3048@2|Bacteria,1TPAH@1239|Firmicutes,4HANC@91061|Bacilli,1ZASU@1386|Bacillus 91061|Bacilli E Belongs to the serine threonine dehydratase family. DsdA subfamily dsdA GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008721,GO:0009987,GO:0016829,GO:0016840,GO:0016841,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564 4.3.1.18 ko:K01753 ko00260,map00260 - R00221 RC02600 ko00000,ko00001,ko01000 - - - PALP k141_11005_1 1347086.CCBA010000011_gene1633 4.43e-34 123.0 2A2R1@1|root,30R3Y@2|Bacteria,1U9MP@1239|Firmicutes,4IJT4@91061|Bacilli,1ZE7Q@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_2728_1 1116375.VEJY3_19131 8.97e-308 876.0 COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1RPRH@1236|Gammaproteobacteria,1XSQZ@135623|Vibrionales 135623|Vibrionales T COG0642 Signal transduction histidine kinase - - 2.7.13.3 ko:K07679 ko02020,ko05133,map02020,map05133 M00477 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,Hpt,Response_reg,SBP_bac_3 k141_1465_2 1116375.VEJY3_01520 6.88e-29 113.0 COG0729@1|root,COG0729@2|Bacteria,1MUKM@1224|Proteobacteria,1RNQ3@1236|Gammaproteobacteria,1XV1N@135623|Vibrionales 135623|Vibrionales M COG0729 Outer membrane protein ytfM - - ko:K07278 - - - - ko00000,ko02000 1.B.33.2.4 - - Bac_surface_Ag,POTRA,POTRA_TamA_1 k141_13471_1 1122134.KB893651_gene1897 2.81e-132 390.0 COG1914@1|root,COG1914@2|Bacteria,1MW6X@1224|Proteobacteria,1RNA2@1236|Gammaproteobacteria,1XMVS@135619|Oceanospirillales 135619|Oceanospirillales P H( )-stimulated, divalent metal cation uptake system mntH - - ko:K03322 - - - - ko00000,ko02000 2.A.55.2.6,2.A.55.3 - - Nramp k141_13471_2 1042377.AFPJ01000055_gene957 3.94e-135 407.0 COG2366@1|root,COG2366@2|Bacteria,1MVMH@1224|Proteobacteria,1RMPX@1236|Gammaproteobacteria,464PP@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG2366 Protein related to penicillin acylase pvdQ - 3.5.1.97 ko:K07116 - - - - ko00000,ko01000 - - - Penicil_amidase k141_22950_1 1294265.JCM21738_3478 7.69e-136 392.0 COG0504@1|root,COG0504@2|Bacteria,1TP34@1239|Firmicutes,4H9X6@91061|Bacilli,1ZB0S@1386|Bacillus 91061|Bacilli F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates pyrG - 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 - - - CTP_synth_N,GATase k141_421_1 1116375.VEJY3_00795 2.37e-198 553.0 COG4239@1|root,COG4239@2|Bacteria,1MUM5@1224|Proteobacteria,1RNUH@1236|Gammaproteobacteria,1XT25@135623|Vibrionales 135623|Vibrionales P transport system permease component yejE - - ko:K13895 ko02010,map02010 M00349 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.21,3.A.1.5.24 - - BPD_transp_1 k141_421_2 1116375.VEJY3_00800 0.0 997.0 COG4166@1|root,COG4166@2|Bacteria,1MUVU@1224|Proteobacteria,1RMA1@1236|Gammaproteobacteria,1XUMM@135623|Vibrionales 135623|Vibrionales E ABC-type oligopeptide transport system, periplasmic component - - - ko:K13893 ko02010,map02010 M00349 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.21,3.A.1.5.24 - - SBP_bac_5 k141_20466_1 218284.CCDN010000001_gene509 1.29e-71 226.0 COG0281@1|root,COG0281@2|Bacteria,1TPJ3@1239|Firmicutes,4H9WR@91061|Bacilli,1ZBAH@1386|Bacillus 91061|Bacilli C Malate dehydrogenase ytsJ - 1.1.1.38 ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 - R00214 RC00105 ko00000,ko00001,ko01000 - - - Malic_M,malic k141_5078_1 1294265.JCM21738_2435 2.6e-147 422.0 COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,4HA95@91061|Bacilli,1ZCW9@1386|Bacillus 91061|Bacilli E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids alr - 5.1.1.1,5.1.1.5 ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 - R00401 RC00285 ko00000,ko00001,ko01000,ko01011 - - - Ala_racemase_C,Ala_racemase_N k141_14563_1 1273538.G159_09200 2.94e-64 206.0 COG3266@1|root,COG3266@2|Bacteria,1V5SZ@1239|Firmicutes,4HHMS@91061|Bacilli,26HAA@186818|Planococcaceae 91061|Bacilli S domain, Protein - - - - - - - - - - - - ChapFlgA,SAF k141_12317_1 1294265.JCM21738_2770 6.24e-145 413.0 COG1484@1|root,COG1484@2|Bacteria,1TPZX@1239|Firmicutes,4HABS@91061|Bacilli,1ZB6G@1386|Bacillus 91061|Bacilli L Primosomal protein DnaI dnaI GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - ko:K11144 - - - - ko00000,ko03032 - - - DnaI_N,IstB_IS21 k141_13472_1 218284.CCDN010000001_gene563 8.01e-42 145.0 COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,4HAE2@91061|Bacilli,1ZBCR@1386|Bacillus 91061|Bacilli C Electron transfer flavoprotein etfA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 - ko:K03522 - - - - ko00000,ko04147 - - - ETF,ETF_alpha k141_24080_1 997296.PB1_03110 2.99e-89 279.0 COG0367@1|root,COG0367@2|Bacteria,1TRPB@1239|Firmicutes,4HA44@91061|Bacilli,1ZBY8@1386|Bacillus 91061|Bacilli E Asparagine synthase asnO - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 k141_19327_1 218284.CCDN010000002_gene2214 2.56e-42 149.0 COG0477@1|root,COG2814@2|Bacteria,1TSR2@1239|Firmicutes,4HD8G@91061|Bacilli,1ZCGV@1386|Bacillus 91061|Bacilli EGP COG0477 Permeases of the major facilitator superfamily - - - - - - - - - - - - MFS_1,MFS_3 k141_24287_2 935836.JAEL01000006_gene2845 1.47e-19 84.7 2BM31@1|root,32FK5@2|Bacteria,1UAUV@1239|Firmicutes,4IM7Q@91061|Bacilli,1ZJF4@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - DUF3892 k141_8955_1 349521.HCH_00138 1.92e-12 67.0 COG0665@1|root,COG0665@2|Bacteria,1N1TN@1224|Proteobacteria,1RPIZ@1236|Gammaproteobacteria,1XJBI@135619|Oceanospirillales 135619|Oceanospirillales E FAD dependent oxidoreductase - - 1.4.3.19 ko:K03153 ko00730,ko01100,map00730,map01100 - R07463 RC01788 ko00000,ko00001,ko01000 - - - DAO k141_8955_2 1279017.AQYJ01000026_gene398 0.0 1144.0 COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,1RP1F@1236|Gammaproteobacteria,465SM@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction thiC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 ko:K03147 ko00730,ko01100,map00730,map01100 M00127 R03472 RC03251,RC03252 ko00000,ko00001,ko00002,ko01000 - - iECABU_c1320.ECABU_c45100 ThiC-associated,ThiC_Rad_SAM k141_5413_1 1132442.KB889752_gene2731 1.01e-109 326.0 COG0451@1|root,COG0451@2|Bacteria,1VP6I@1239|Firmicutes,4HAN7@91061|Bacilli,1ZQ48@1386|Bacillus 91061|Bacilli M NAD-dependent epimerase dehydratase - - 5.1.3.6 ko:K08679 ko00520,ko01100,map00520,map01100 - R01385 RC00289 ko00000,ko00001,ko01000 - - - Epimerase,GDP_Man_Dehyd k141_21944_1 1246484.D479_17509 5.59e-53 182.0 COG0154@1|root,COG0154@2|Bacteria,1TP0C@1239|Firmicutes,4HBAZ@91061|Bacilli,3NDYD@45667|Halobacillus 91061|Bacilli J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) - - 3.5.1.4,3.5.1.54 ko:K01426,ko:K01457 ko00220,ko00330,ko00360,ko00380,ko00627,ko00643,ko00791,ko01100,ko01120,map00220,map00330,map00360,map00380,map00627,map00643,map00791,map01100,map01120 - R00005,R02540,R03096,R03180,R03909,R05551,R05590 RC00010,RC00100,RC00950,RC01025,RC02756 ko00000,ko00001,ko01000 - - - Amidase k141_2882_1 1031711.RSPO_c02710 2.24e-14 75.5 COG4960@1|root,COG4960@2|Bacteria,1N7J0@1224|Proteobacteria,2VWBT@28216|Betaproteobacteria,1K8UT@119060|Burkholderiaceae 28216|Betaproteobacteria OU peptidase A24A prepilin type IV cpaA1 - 3.4.23.43 ko:K02278 - - - - ko00000,ko01000,ko02035,ko02044 - - - Peptidase_A24 k141_35070_1 935836.JAEL01000003_gene498 2.2e-29 105.0 2EH2H@1|root,33AUF@2|Bacteria,1VKXK@1239|Firmicutes,4HRIP@91061|Bacilli,1ZIU3@1386|Bacillus 91061|Bacilli S asexual reproduction sspH - - ko:K06425 - - - - ko00000 - - - SspH k141_12627_1 42565.FP66_02805 1.86e-57 179.0 COG3027@1|root,COG3027@2|Bacteria,1N6YN@1224|Proteobacteria,1SCBI@1236|Gammaproteobacteria,1XM8P@135619|Oceanospirillales 135619|Oceanospirillales D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division zapA - - ko:K09888 - - - - ko00000,ko03036 - - - ZapA k141_12627_2 42565.FP66_02810 3.42e-11 60.8 COG3079@1|root,COG3079@2|Bacteria,1QSYH@1224|Proteobacteria,1RWKP@1236|Gammaproteobacteria,1XMFC@135619|Oceanospirillales 135619|Oceanospirillales S Belongs to the UPF0149 family - - - ko:K09895 - - - - ko00000 - - - UPF0149 k141_1662_1 1279017.AQYJ01000024_gene1066 3.65e-79 236.0 COG2969@1|root,COG2969@2|Bacteria,1MZ2Q@1224|Proteobacteria,1S8WT@1236|Gammaproteobacteria,467R0@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG2969 Stringent starvation protein B sspB GO:0000502,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0009376,GO:0009893,GO:0009894,GO:0009896,GO:0010604,GO:0019222,GO:0019899,GO:0031597,GO:0032781,GO:0032991,GO:0042176,GO:0042802,GO:0042803,GO:0043085,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043462,GO:0044093,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0045732,GO:0046983,GO:0048518,GO:0050789,GO:0050790,GO:0051117,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051336,GO:0051345,GO:0060255,GO:0065007,GO:0065009,GO:0080090,GO:0097159,GO:1901363,GO:1902494,GO:1904949,GO:1905368,GO:1905369,GO:1990904 - ko:K03600 - - - - ko00000,ko03021 - - - SspB k141_13808_1 1042377.AFPJ01000014_gene1667 3.4e-54 185.0 28J16@1|root,2Z8Y7@2|Bacteria,1R657@1224|Proteobacteria,1SFYP@1236|Gammaproteobacteria,46BM2@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_13808_2 1453501.JELR01000001_gene2963 1.65e-108 320.0 2ACR0@1|root,312BP@2|Bacteria,1NG36@1224|Proteobacteria,1SH59@1236|Gammaproteobacteria,46BQC@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_13808_3 1453501.JELR01000001_gene2962 4.25e-163 459.0 COG2908@1|root,COG2908@2|Bacteria,1MVKD@1224|Proteobacteria,1RQIA@1236|Gammaproteobacteria,464YT@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria HA62_17960 - - - - - - - - - - - Metallophos,Metallophos_2 k141_37342_1 1120998.AUFC01000008_gene1067 6.04e-14 76.3 COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia,3WCF4@538999|Clostridiales incertae sedis 186801|Clostridia L Helix-hairpin-helix motif dnaE - 2.7.7.7 ko:K02337,ko:K14162 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon k141_37342_2 861299.J421_2655 1.4e-69 220.0 COG0825@1|root,COG0825@2|Bacteria,1ZSW6@142182|Gemmatimonadetes 142182|Gemmatimonadetes I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA accA - 2.1.3.15,6.4.1.2 ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - ACCA k141_10198_1 491952.Mar181_3363 3.29e-88 289.0 COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,1RMK0@1236|Gammaproteobacteria,1XHCD@135619|Oceanospirillales 135619|Oceanospirillales K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoB - 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 k141_17166_1 218284.CCDN010000010_gene4373 1.05e-316 893.0 COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,4HA24@91061|Bacilli,1ZDK0@1386|Bacillus 91061|Bacilli K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoC GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 k141_36109_2 218284.CCDN010000001_gene603 2.3e-45 154.0 COG1587@1|root,COG1587@2|Bacteria,1UHSJ@1239|Firmicutes,4HFY4@91061|Bacilli,1ZGER@1386|Bacillus 91061|Bacilli H Uroporphyrinogen-III synthase hemD - 4.2.1.75 ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R03165 RC01861 ko00000,ko00001,ko00002,ko01000 - - - HEM4 k141_18501_2 158500.BV97_04889 9.1e-12 65.9 COG1972@1|root,COG1972@2|Bacteria,1MXXX@1224|Proteobacteria,2TU8A@28211|Alphaproteobacteria,2K07T@204457|Sphingomonadales 204457|Sphingomonadales F nucleoside - - - ko:K03317 - - - - ko00000 2.A.41 - - Gate,Nucleos_tra2_C,Nucleos_tra2_N k141_35071_1 399739.Pmen_1857 8.42e-137 399.0 COG0677@1|root,COG0677@2|Bacteria,1MUC6@1224|Proteobacteria,1RMX0@1236|Gammaproteobacteria,1YECS@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria M UDP binding domain wbpA - 1.1.1.136 ko:K13015 ko00520,map00520 - R00421 RC00291 ko00000,ko00001,ko01000,ko01005 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N k141_32531_1 1042377.AFPJ01000009_gene248 1.18e-11 63.5 COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,1RSQ3@1236|Gammaproteobacteria,46786@72275|Alteromonadaceae 1236|Gammaproteobacteria P Rhodanese Homology Domain sseA - 2.8.1.1,2.8.1.2 ko:K01011 ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122 - R01931,R03105,R03106 RC00214 ko00000,ko00001,ko01000 - - - Rhodanese k141_32531_3 1453501.JELR01000001_gene2161 1.36e-120 347.0 COG3897@1|root,COG3897@2|Bacteria,1RJUI@1224|Proteobacteria,1S6V9@1236|Gammaproteobacteria,468S5@72275|Alteromonadaceae 1236|Gammaproteobacteria S Lysine methyltransferase - - - - - - - - - - - - Methyltransf_16,Methyltransf_25 k141_30144_1 1340434.AXVA01000013_gene308 2.76e-127 369.0 COG0413@1|root,COG0413@2|Bacteria,1TPZA@1239|Firmicutes,4H9S8@91061|Bacilli,1ZAWV@1386|Bacillus 91061|Bacilli H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate panB - 2.1.2.11 ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R01226 RC00022,RC00200 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU22430 Pantoate_transf k141_29045_2 1279017.AQYJ01000027_gene1999 2.09e-163 470.0 COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,1RMW3@1236|Gammaproteobacteria,463Y1@72275|Alteromonadaceae 1236|Gammaproteobacteria G Belongs to the pyruvate kinase family pykA GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016043,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - e_coli_core.b1854,iAF1260.b1854,iB21_1397.B21_01813,iBWG_1329.BWG_1668,iEC042_1314.EC042_2021,iECBD_1354.ECBD_1784,iECB_1328.ECB_01825,iECDH10B_1368.ECDH10B_1995,iECDH1ME8569_1439.ECDH1ME8569_1801,iECD_1391.ECD_01825,iECO103_1326.ECO103_2044,iECO111_1330.ECO111_2362,iECO26_1355.ECO26_2692,iECUMN_1333.ECUMN_2152,iETEC_1333.ETEC_1887,iEcDH1_1363.EcDH1_1786,iEcE24377_1341.EcE24377A_2084,iEcHS_1320.EcHS_A1947,iEcSMS35_1347.EcSMS35_1332,iEcolC_1368.EcolC_1778,iG2583_1286.G2583_2306,iJO1366.b1854,iJR904.b1854,iSBO_1134.SBO_1162,iSSON_1240.SSON_1294,iSbBS512_1146.SbBS512_E2130,iUMNK88_1353.UMNK88_2326,iY75_1357.Y75_RS09740 PK,PK_C k141_13809_1 218284.CCDN010000001_gene190 4.46e-76 247.0 COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,4HA3G@91061|Bacilli,1ZAVY@1386|Bacillus 91061|Bacilli T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,PAS_4,PAS_9 k141_20716_1 1089447.RHAA1_07311 2.17e-17 87.0 COG3283@1|root,COG3283@2|Bacteria,1QTS3@1224|Proteobacteria,1SMRY@1236|Gammaproteobacteria,1YATR@135625|Pasteurellales 135625|Pasteurellales K Protein involved in ATP binding, DNA binding, protein binding, transcription factor binding, regulation of transcription DNA-dependent and regulation of transcription tyrR GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K03721 - - - - ko00000,ko03000 - - - Sigma54_activat k141_20716_2 1042377.AFPJ01000009_gene236 7.6e-56 176.0 COG4323@1|root,COG4323@2|Bacteria,1N16T@1224|Proteobacteria,1S8V6@1236|Gammaproteobacteria,4683B@72275|Alteromonadaceae 1236|Gammaproteobacteria S membrane - - - - - - - - - - - - DUF962 k141_20716_3 1279017.AQYJ01000025_gene668 9.93e-255 703.0 COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,1RNB5@1236|Gammaproteobacteria,465FA@72275|Alteromonadaceae 1236|Gammaproteobacteria C acyl-CoA transferases carnitine dehydratase coaT - - - - - - - - - - - CoA_transf_3 k141_20716_4 1523503.JPMY01000023_gene978 3.19e-17 82.4 COG1077@1|root,COG1077@2|Bacteria,1RK8H@1224|Proteobacteria,1S8CX@1236|Gammaproteobacteria 1236|Gammaproteobacteria D MreB/Mbl protein - - - ko:K03569 - - - - ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 - - MreB_Mbl k141_20716_5 1479237.JMLY01000001_gene2641 0.0 896.0 COG2936@1|root,COG2936@2|Bacteria,1MVA8@1224|Proteobacteria,1S1KH@1236|Gammaproteobacteria,468RG@72275|Alteromonadaceae 1236|Gammaproteobacteria S X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain - - - ko:K06978 - - - - ko00000 - - - PepX_C,Peptidase_S15 k141_20716_6 1283300.ATXB01000002_gene3165 2.22e-168 487.0 COG0439@1|root,COG0439@2|Bacteria,1QXYJ@1224|Proteobacteria,1T4PS@1236|Gammaproteobacteria 1236|Gammaproteobacteria I ATP-grasp domain - - - - - - - - - - - - ATP-grasp_4 k141_20716_7 1042377.AFPJ01000009_gene234 5.16e-140 404.0 COG0668@1|root,COG0668@2|Bacteria,1QU7U@1224|Proteobacteria,1T2B5@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Mechanosensitive ion channel - - - - - - - - - - - - MS_channel k141_7647_1 675806.VII_000010 2.33e-38 135.0 COG0583@1|root,COG0583@2|Bacteria,1MU2E@1224|Proteobacteria,1RQ66@1236|Gammaproteobacteria,1XXB6@135623|Vibrionales 135623|Vibrionales K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate k141_7647_2 1219076.N646_4548 1.15e-199 554.0 COG1073@1|root,COG1073@2|Bacteria,1MUCD@1224|Proteobacteria,1RP4I@1236|Gammaproteobacteria,1XW6W@135623|Vibrionales 135623|Vibrionales S of the alpha beta superfamily - - - ko:K06889 - - - - ko00000 - - - DLH,Hydrolase_4 k141_36130_1 1279017.AQYJ01000024_gene1063 2.4e-126 361.0 COG0723@1|root,COG0723@2|Bacteria,1RAA2@1224|Proteobacteria,1RP9H@1236|Gammaproteobacteria,465S7@72275|Alteromonadaceae 1236|Gammaproteobacteria C Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis petA - 1.10.2.2 ko:K00411 ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152 - - ko00000,ko00001,ko00002,ko01000 - - - Rieske,UCR_Fe-S_N k141_13852_1 574375.BAGA_19055 4.51e-26 111.0 COG0749@1|root,COG0749@2|Bacteria,1V02Y@1239|Firmicutes,4HD34@91061|Bacilli,1ZM2A@1386|Bacillus 91061|Bacilli L 3'-5' exonuclease - - - - - - - - - - - - DNA_pol_A,DNA_pol_A_exo1 k141_19646_1 1042377.AFPJ01000020_gene2039 2.75e-78 256.0 COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,1RMA7@1236|Gammaproteobacteria,465DP@72275|Alteromonadaceae 1236|Gammaproteobacteria E aminopeptidase N pepN GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0009056,GO:0009987,GO:0016020,GO:0016787,GO:0019538,GO:0033218,GO:0034641,GO:0042277,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - iECIAI1_1343.ECIAI1_0973,iECO103_1326.ECO103_0977,iECP_1309.ECP_0944,iECSE_1348.ECSE_0993,iECW_1372.ECW_m1042,iEKO11_1354.EKO11_2898,iWFL_1372.ECW_m1042 DUF3458,DUF3458_C,Peptidase_M1 k141_23277_1 1121015.N789_00780 3.4e-59 199.0 COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,1RQ0H@1236|Gammaproteobacteria,1X541@135614|Xanthomonadales 135614|Xanthomonadales E Threonine synthase thrC - 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 - - - PALP,Thr_synth_N k141_24335_1 218284.CCDN010000001_gene1304 1.23e-171 490.0 COG1292@1|root,COG1292@2|Bacteria,1TRS6@1239|Firmicutes,4HA7U@91061|Bacilli,1ZBRN@1386|Bacillus 91061|Bacilli M Belongs to the BCCT transporter (TC 2.A.15) family - - - ko:K05020 - - - - ko00000,ko02000 2.A.15.1.1,2.A.15.1.11 - - BCCT k141_6570_1 218284.CCDN010000008_gene4204 3.65e-141 404.0 COG1363@1|root,COG1363@2|Bacteria,1TNZT@1239|Firmicutes,4H9SM@91061|Bacilli,1ZAXE@1386|Bacillus 91061|Bacilli G COG1363 Cellulase M and related proteins pepA - 3.4.11.7 ko:K01261,ko:K01269 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M42 k141_21975_1 1395587.P364_0129705 0.000344 43.5 COG0697@1|root,COG0697@2|Bacteria,1VCE8@1239|Firmicutes,4IQX1@91061|Bacilli,276JE@186822|Paenibacillaceae 91061|Bacilli EG Multidrug transporter - - - - - - - - - - - - EamA k141_21975_2 935836.JAEL01000014_gene2060 1.96e-52 173.0 COG1284@1|root,COG1284@2|Bacteria,1TR9J@1239|Firmicutes,4H9N6@91061|Bacilli,1ZC8U@1386|Bacillus 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2179) XK27_10395 - - - - - - - - - - - DUF2179,YitT_membrane k141_16025_1 42565.FP66_07325 5.14e-85 255.0 COG0024@1|root,COG0024@2|Bacteria,1MU99@1224|Proteobacteria,1RMHN@1236|Gammaproteobacteria,1XIAD@135619|Oceanospirillales 135619|Oceanospirillales E Methionine aminopeptidase map - 3.4.11.18 ko:K01265 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M24 k141_5448_1 1116375.VEJY3_03345 0.0 963.0 COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,1RP14@1236|Gammaproteobacteria,1XTP8@135623|Vibrionales 135623|Vibrionales J Belongs to the class-I aminoacyl-tRNA synthetase family leuS - 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Anticodon_1,tRNA-synt_1,tRNA-synt_1_2 k141_5448_2 1116375.VEJY3_03340 1.03e-104 305.0 COG2980@1|root,COG2980@2|Bacteria,1N0JN@1224|Proteobacteria,1SAG4@1236|Gammaproteobacteria,1XUHF@135623|Vibrionales 135623|Vibrionales M Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane lptE - - ko:K03643 - - - - ko00000,ko02000 1.B.42.1 - - LptE k141_5448_3 1116375.VEJY3_03335 5.15e-225 622.0 COG1466@1|root,COG1466@2|Bacteria,1MWYT@1224|Proteobacteria,1RQRE@1236|Gammaproteobacteria,1XUE0@135623|Vibrionales 135623|Vibrionales L DNA polymerase III, delta subunit holA - 2.7.7.7 ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delt_C,DNA_pol3_delta k141_5448_4 223926.28805710 4.23e-68 206.0 COG0799@1|root,COG0799@2|Bacteria,1MZEF@1224|Proteobacteria,1S8W3@1236|Gammaproteobacteria,1XXWJ@135623|Vibrionales 135623|Vibrionales J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation rsfS - - ko:K09710 - - - - ko00000,ko03009 - - - RsfS k141_5448_5 1116375.VEJY3_03325 3.61e-104 301.0 COG1576@1|root,COG1576@2|Bacteria,1R9Z2@1224|Proteobacteria,1S1ZY@1236|Gammaproteobacteria,1XSIT@135623|Vibrionales 135623|Vibrionales J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA rlmH - 2.1.1.177 ko:K00783 - - - - ko00000,ko01000,ko03009 - - - SPOUT_MTase k141_5448_6 223926.28805708 7.31e-288 797.0 COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,1RN9H@1236|Gammaproteobacteria,1XTJ2@135623|Vibrionales 135623|Vibrionales M Catalyzes cross-linking of the peptidoglycan cell wall mrdA - 3.4.16.4 ko:K05515 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - - PBP_dimer,Transpeptidase k141_30159_1 218284.CCDN010000001_gene1087 6.19e-70 211.0 2BY17@1|root,33W84@2|Bacteria,1VVVY@1239|Firmicutes,4HWE5@91061|Bacilli,1ZHY9@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_13853_1 1034347.CAHJ01000062_gene975 9.73e-110 328.0 COG0277@1|root,COG0277@2|Bacteria,1TPBC@1239|Firmicutes,4H9UU@91061|Bacilli,1ZCHD@1386|Bacillus 91061|Bacilli C FAD linked oxidases, C-terminal domain glcD - 1.1.3.15 ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001,ko01000 - - - FAD-oxidase_C,FAD_binding_4 k141_33895_1 1336245.JAGO01000015_gene2052 1.63e-29 108.0 COG0251@1|root,COG0251@2|Bacteria,1RG2H@1224|Proteobacteria,1RSJD@1236|Gammaproteobacteria 1236|Gammaproteobacteria J translation initiation inhibitor, yjgF family - - 3.5.99.10 ko:K09022 - - R11098,R11099 RC03275,RC03354 ko00000,ko01000 - - - Ribonuc_L-PSP k141_33895_2 1323663.AROI01000024_gene1552 7.77e-155 440.0 COG1402@1|root,COG1402@2|Bacteria,1MXR9@1224|Proteobacteria,1RR9A@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Creatininase - - 3.5.2.10 ko:K01470 ko00330,map00330 - R01884 RC00615 ko00000,ko00001,ko01000 - - - Creatininase k141_33895_3 1151116.Q7S_09260 4.03e-118 350.0 COG0715@1|root,COG0715@2|Bacteria,1MXA3@1224|Proteobacteria,1RY6B@1236|Gammaproteobacteria,3FG0Y@34037|Rahnella 1236|Gammaproteobacteria P NMT1/THI5 like - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1 k141_26985_1 1453501.JELR01000002_gene548 1.08e-45 155.0 2E6EA@1|root,3311R@2|Bacteria,1PFMW@1224|Proteobacteria,1SIKE@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Outer membrane protein beta-barrel domain - - - - - - - - - - - - OMP_b-brl k141_23278_1 218284.CCDN010000001_gene661 9.83e-106 327.0 COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,1TQVT@1239|Firmicutes,4HB6K@91061|Bacilli,1ZBS9@1386|Bacillus 91061|Bacilli U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secD GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD_SecF,Sec_GG k141_27753_1 1294265.JCM21738_4737 1.7e-52 183.0 COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H9SA@91061|Bacilli,1ZD7B@1386|Bacillus 91061|Bacilli M COG0744 Membrane carboxypeptidase (penicillin-binding protein) pbp1B - 2.4.1.129 ko:K03693,ko:K12551 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase k141_14780_1 218284.CCDN010000008_gene4144 2.52e-115 337.0 COG0596@1|root,COG0596@2|Bacteria,1TS4C@1239|Firmicutes,4HB6G@91061|Bacilli,1ZAU9@1386|Bacillus 91061|Bacilli S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) menH GO:0003674,GO:0003824,GO:0016787 4.2.99.20 ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R08166 RC02148,RC02475 ko00000,ko00001,ko00002,ko01000 - - - Abhydrolase_1 k141_29071_1 1453501.JELR01000002_gene1144 1.22e-85 280.0 COG2304@1|root,COG2931@1|root,COG3210@1|root,COG2304@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,1R1GH@1224|Proteobacteria,1T525@1236|Gammaproteobacteria 1236|Gammaproteobacteria U oxidoreductase activity - - - - - - - - - - - - - k141_18520_1 1116375.VEJY3_16071 3.61e-130 370.0 COG1280@1|root,COG1280@2|Bacteria,1RET0@1224|Proteobacteria,1S322@1236|Gammaproteobacteria,1XW5A@135623|Vibrionales 135623|Vibrionales E threonine efflux protein - - - - - - - - - - - - LysE k141_18520_2 1116375.VEJY3_16066 4.79e-112 327.0 COG2375@1|root,COG2375@2|Bacteria,1R4TD@1224|Proteobacteria,1RY01@1236|Gammaproteobacteria,1XTJW@135623|Vibrionales 135623|Vibrionales P Siderophore-interacting protein - - - - - - - - - - - - FAD_binding_9,SIP k141_19647_2 935837.JAEK01000029_gene1791 2.67e-16 73.2 COG3695@1|root,COG3695@2|Bacteria,1VC8H@1239|Firmicutes,4HKXS@91061|Bacilli,1ZI3E@1386|Bacillus 91061|Bacilli L 6-O-methylguanine DNA methyltransferase, DNA binding domain MGMT - - ko:K07443 - - - - ko00000 - - - DNA_binding_1 k141_6571_1 323261.Noc_0294 8.18e-64 220.0 COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,1RNIF@1236|Gammaproteobacteria,1WX26@135613|Chromatiales 135613|Chromatiales P Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran k141_6571_2 1121935.AQXX01000099_gene1224 1.18e-36 133.0 COG2207@1|root,COG3449@1|root,COG2207@2|Bacteria,COG3449@2|Bacteria,1MWTF@1224|Proteobacteria,1RMKE@1236|Gammaproteobacteria,1XKHR@135619|Oceanospirillales 135619|Oceanospirillales K Bacterial transcription activator, effector binding domain - - - ko:K13652 - - - - ko00000,ko03000 - - - GyrI-like,HTH_18 k141_20741_1 1279017.AQYJ01000021_gene2801 1.06e-84 260.0 COG3249@1|root,COG3249@2|Bacteria,1N0PD@1224|Proteobacteria,1S9C4@1236|Gammaproteobacteria,466SQ@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria VV2512 - - ko:K09938 - - - - ko00000 - - - DUF2066 k141_12660_1 1116375.VEJY3_18406 1.44e-274 763.0 COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,1RPNE@1236|Gammaproteobacteria,1Y04N@135623|Vibrionales 135623|Vibrionales I AMP-binding enzyme - - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding k141_2902_1 218284.CCDN010000001_gene685 6.61e-181 525.0 COG0507@1|root,COG0507@2|Bacteria,1TPZH@1239|Firmicutes,4HATQ@91061|Bacilli,1ZAYS@1386|Bacillus 91061|Bacilli L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity recD2 - 3.1.11.5 ko:K03581 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_30,HHH_4,HHH_5,UvrD_C_2 k141_27754_1 665959.HMPREF1013_00468 5.65e-46 162.0 COG4552@1|root,COG4552@2|Bacteria,1TRPM@1239|Firmicutes,4HD22@91061|Bacilli,1ZB8R@1386|Bacillus 91061|Bacilli S Acetyltransferase - - - - - - - - - - - - Acetyltransf_9,SCP2_2 k141_1695_1 1116375.VEJY3_22066 6.3e-224 622.0 COG0814@1|root,COG0814@2|Bacteria,1NSWF@1224|Proteobacteria,1SM8N@1236|Gammaproteobacteria,1XTEM@135623|Vibrionales 135623|Vibrionales U COG0814 Amino acid permeases - - - ko:K03834 - - - - ko00000,ko02000 2.A.42.1.1 - - Trp_Tyr_perm k141_7648_1 698737.SLGD_02278 6.27e-32 119.0 2E5K5@1|root,330BC@2|Bacteria,1VGEJ@1239|Firmicutes,4IS2J@91061|Bacilli 91061|Bacilli S Siphovirus Gp157 - - - - - - - - - - - - Sipho_Gp157 k141_35115_2 218284.CCDN010000002_gene2087 8.55e-104 301.0 COG2151@1|root,COG2151@2|Bacteria,1V3QG@1239|Firmicutes,4HHST@91061|Bacilli,1ZBJH@1386|Bacillus 91061|Bacilli S Iron-sulfur cluster assembly protein paaD - - ko:K02612 ko00360,ko01120,map00360,map01120 - R09838 RC02690 ko00000,ko00001 - - - FeS_assembly_P k141_35115_3 218284.CCDN010000002_gene2086 1.71e-117 340.0 COG3396@1|root,COG3396@2|Bacteria,1TPWQ@1239|Firmicutes,4HCRX@91061|Bacilli,1ZB84@1386|Bacillus 91061|Bacilli Q Phenylacetic acid catabolic protein paaC - 1.14.13.149 ko:K02611 ko00360,ko01120,map00360,map01120 - R09838 RC02690 ko00000,ko00001,ko01000 - - - PaaA_PaaC k141_25675_1 1042377.AFPJ01000014_gene1650 3.14e-87 257.0 COG2927@1|root,COG2927@2|Bacteria,1MZ3V@1224|Proteobacteria,1S94K@1236|Gammaproteobacteria,467ZQ@72275|Alteromonadaceae 1236|Gammaproteobacteria L DNA polymerase III chi subunit holC GO:0005575,GO:0005622,GO:0005623,GO:0006275,GO:0008150,GO:0009314,GO:0009360,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010556,GO:0010557,GO:0010604,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032298,GO:0032991,GO:0042575,GO:0043846,GO:0043847,GO:0044424,GO:0044464,GO:0045740,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051054,GO:0051171,GO:0051173,GO:0060255,GO:0061695,GO:0065007,GO:0080090,GO:0090329,GO:1902494,GO:1990234,GO:2000105,GO:2000112 2.7.7.7 ko:K02339 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_chi k141_25675_2 1453501.JELR01000001_gene2948 3.26e-12 65.1 2EPR3@1|root,33HBJ@2|Bacteria,1NH9J@1224|Proteobacteria,1SHY3@1236|Gammaproteobacteria,4699X@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_10244_2 218284.CCDN010000007_gene3804 4.61e-19 85.1 COG0668@1|root,COG0668@2|Bacteria,1TR9Z@1239|Firmicutes,4HCB8@91061|Bacilli,1ZCW4@1386|Bacillus 91061|Bacilli M Mechanosensitive ion channel ykuT - - ko:K22044 - - - - ko00000,ko02000 1.A.23.3 - - MS_channel k141_36132_1 1071073.KI530538_gene260 4.08e-11 62.8 COG0381@1|root,COG0381@2|Bacteria,1TQZT@1239|Firmicutes,4HBI3@91061|Bacilli,1ZCZG@1386|Bacillus 91061|Bacilli M Belongs to the UDP-N-acetylglucosamine 2-epimerase family mnaA - 5.1.3.14 ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 M00362 R00420 RC00290 ko00000,ko00001,ko00002,ko01000,ko01005 - - iSB619.SA_RS11005 Epimerase_2 k141_12661_1 856793.MICA_2202 1.24e-84 258.0 COG0657@1|root,COG0657@2|Bacteria,1N2XW@1224|Proteobacteria,2U3QT@28211|Alphaproteobacteria,4BT8C@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria I Carboxylesterase family - - - - - - - - - - - - Abhydrolase_3,COesterase,Peptidase_S9 k141_29072_1 1042377.AFPJ01000036_gene1137 4.21e-57 199.0 COG1629@1|root,COG1629@2|Bacteria,1MVSG@1224|Proteobacteria,1RS33@1236|Gammaproteobacteria,46A68@72275|Alteromonadaceae 1236|Gammaproteobacteria P Carboxypeptidase regulatory-like domain - - - - - - - - - - - - CarboxypepD_reg k141_27755_1 218284.CCDN010000005_gene3179 2.06e-96 280.0 COG0537@1|root,COG0537@2|Bacteria,1V9ZJ@1239|Firmicutes,4HIG2@91061|Bacilli,1ZGI0@1386|Bacillus 91061|Bacilli FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases hit - - ko:K02503 - - - - ko00000,ko04147 - - - HIT k141_17199_2 1453501.JELR01000006_gene35 0.0 1062.0 COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,1RMIQ@1236|Gammaproteobacteria,464S3@72275|Alteromonadaceae 1236|Gammaproteobacteria U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secD GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - ko:K03072 ko03060,ko03070,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD-TM1,SecD_SecF,Sec_GG k141_17199_3 1453501.JELR01000006_gene34 7.07e-188 528.0 COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,1RNTY@1236|Gammaproteobacteria,464WJ@72275|Alteromonadaceae 1236|Gammaproteobacteria U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secF GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - ko:K03074 ko03060,ko03070,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD_SecF,Sec_GG k141_20742_2 218284.CCDN010000001_gene1911 5.62e-76 236.0 COG1419@1|root,COG1419@2|Bacteria,1TSP7@1239|Firmicutes,4H9VG@91061|Bacilli,1ZCJ9@1386|Bacillus 91061|Bacilli N Flagellar biosynthesis regulator FlhF flhF GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K02404 - - - - ko00000,ko02035 - - - SRP54 k141_25676_1 218284.CCDN010000002_gene2508 6.06e-106 318.0 COG1233@1|root,COG1233@2|Bacteria,1TQX8@1239|Firmicutes,4HBEI@91061|Bacilli,1ZBFN@1386|Bacillus 91061|Bacilli Q Flavin containing amine oxidoreductase crtP - 1.14.99.44 ko:K10210 ko00906,map00906 - R07654,R09671,R09727,R09728 RC00254,RC02089,RC02626,RC02638 ko00000,ko00001,ko01000 - - - Amino_oxidase k141_26986_1 1307436.PBF_03375 7.26e-41 149.0 COG0366@1|root,COG0366@2|Bacteria,1TSVI@1239|Firmicutes,4HCV2@91061|Bacilli,1ZDR6@1386|Bacillus 91061|Bacilli G Alpha amylase, catalytic domain - - 3.2.1.1 ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 - R02108,R02112,R11262 - ko00000,ko00001,ko01000 - GH13 - Alpha-amylase k141_26986_2 218284.CCDN010000005_gene3252 1.57e-189 530.0 COG1609@1|root,COG1609@2|Bacteria,1TPZM@1239|Firmicutes,4H9ZT@91061|Bacilli,1ZB2U@1386|Bacillus 91061|Bacilli K Transcriptional regulator malR - - - - - - - - - - - LacI,Peripla_BP_3 k141_724_1 218284.CCDN010000001_gene1142 2.76e-112 332.0 COG2333@1|root,COG2333@2|Bacteria,1VI9A@1239|Firmicutes,4HIJR@91061|Bacilli,1ZES1@1386|Bacillus 91061|Bacilli S competence protein COMEC - - - - - - - - - - - - Lactamase_B k141_724_2 218284.CCDN010000001_gene1141 1.11e-161 480.0 COG0847@1|root,COG1199@1|root,COG0847@2|Bacteria,COG1199@2|Bacteria,1TQHQ@1239|Firmicutes,4HB2Y@91061|Bacilli,1ZAWI@1386|Bacillus 91061|Bacilli L helicase involved in DNA repair and perhaps also replication dinG - 3.6.4.12 ko:K03722 - - - - ko00000,ko01000,ko03400 - - - DEAD,Helicase_C_2,RNase_T,ResIII k141_36318_1 715451.ambt_06860 2.28e-13 75.1 COG2199@1|root,COG3706@2|Bacteria,1R895@1224|Proteobacteria,1RSDW@1236|Gammaproteobacteria,467PI@72275|Alteromonadaceae 1236|Gammaproteobacteria T GGDEF domain - - - - - - - - - - - - GAF,GGDEF,PAS,PAS_3,PAS_4 k141_934_2 218284.CCDN010000001_gene578 8.28e-181 503.0 COG0479@1|root,COG0479@2|Bacteria,1TP17@1239|Firmicutes,4HAG7@91061|Bacilli,1ZAPQ@1386|Bacillus 91061|Bacilli C succinate dehydrogenase sdhB GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0022900,GO:0022904,GO:0044237,GO:0044464,GO:0045333,GO:0055114,GO:0071944 1.3.5.1,1.3.5.4 ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - Fer2_3,Fer4_10,Fer4_8 k141_27300_1 1403313.AXBR01000024_gene4706 4.35e-76 231.0 2EUE6@1|root,33MWI@2|Bacteria,1VPQU@1239|Firmicutes,4HGC3@91061|Bacilli,1ZIDQ@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_23625_1 1453501.JELR01000002_gene1110 4.47e-78 252.0 COG4772@1|root,COG4772@2|Bacteria,1MWDG@1224|Proteobacteria,1RQA5@1236|Gammaproteobacteria,464IF@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG4772 Outer membrane receptor for Fe3 -dicitrate fecA - - ko:K16091 - - - - ko00000,ko02000 1.B.14.1.14 - - Plug,TonB_dep_Rec k141_11665_1 218284.CCDN010000001_gene286 1.36e-35 140.0 COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,4H9SP@91061|Bacilli,1ZAPS@1386|Bacillus 91061|Bacilli P COG2217 Cation transport ATPase - - 3.6.3.3,3.6.3.5 ko:K01534 - - - - ko00000,ko01000 3.A.3.6 - - E1-E2_ATPase,HMA,Hydrolase k141_29300_1 1453501.JELR01000001_gene2374 5.4e-75 243.0 COG0642@1|root,COG0784@1|root,COG0642@2|Bacteria,COG0784@2|Bacteria,1R4TJ@1224|Proteobacteria,1RQKQ@1236|Gammaproteobacteria,4671J@72275|Alteromonadaceae 1236|Gammaproteobacteria T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,Response_reg k141_4350_1 218284.CCDN010000001_gene192 1.08e-55 181.0 COG0784@1|root,COG0835@1|root,COG0784@2|Bacteria,COG0835@2|Bacteria,1TRJU@1239|Firmicutes,4HCPT@91061|Bacilli,1ZAYA@1386|Bacillus 91061|Bacilli T Chemotaxis protein CheV cheV GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0044424,GO:0044444,GO:0044464,GO:0050896 - ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - CheW,Response_reg k141_4350_2 218284.CCDN010000001_gene191 1.37e-40 135.0 2ABH1@1|root,310Y3@2|Bacteria,1V4IK@1239|Firmicutes,4HI56@91061|Bacilli,1ZGD1@1386|Bacillus 91061|Bacilli S YkyB-like protein ykyB - - - - - - - - - - - YkyB k141_32818_1 218284.CCDN010000006_gene3601 8e-89 262.0 COG3682@1|root,COG3682@2|Bacteria,1V7EY@1239|Firmicutes,4HIKG@91061|Bacilli,1ZGN7@1386|Bacillus 91061|Bacilli K Penicillinase repressor - - - ko:K02171 ko01501,map01501 M00627 - - ko00000,ko00001,ko00002,ko01504,ko03000 - - - Penicillinase_R k141_32818_3 218284.CCDN010000006_gene3599 2.72e-58 199.0 COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,4HAI0@91061|Bacilli,1ZAVE@1386|Bacillus 91061|Bacilli P P-type ATPase copA - 3.6.3.54 ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - - E1-E2_ATPase,HMA,Hydrolase k141_10417_1 218284.CCDN010000002_gene2161 2.56e-255 704.0 COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4H9KU@91061|Bacilli,1ZBF2@1386|Bacillus 91061|Bacilli G Belongs to the glycosyl hydrolase 1 family bglA7 - 3.2.1.21 ko:K05350 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 - R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - - - Glyco_hydro_1 k141_22282_1 262543.Exig_2961 3.64e-23 96.7 COG1051@1|root,COG1051@2|Bacteria,1VN72@1239|Firmicutes,4HS47@91061|Bacilli 91061|Bacilli F Belongs to the Nudix hydrolase family - - - - - - - - - - - - NUDIX k141_16255_1 1116375.VEJY3_07230 2.8e-100 315.0 COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,1MW3N@1224|Proteobacteria,1RN6N@1236|Gammaproteobacteria,1XTH6@135623|Vibrionales 135623|Vibrionales C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family fdhA - 1.17.1.9 ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001,ko01000 - - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding k141_16255_2 223926.28806505 1.72e-150 422.0 COG0437@1|root,COG0437@2|Bacteria,1MU5T@1224|Proteobacteria,1RRAN@1236|Gammaproteobacteria,1XTNR@135623|Vibrionales 135623|Vibrionales C formate dehydrogenase iron-sulfur subunit fdhB - - ko:K00124 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001 - - - Fer4_7 k141_16255_3 1116375.VEJY3_07240 5.22e-233 643.0 COG2864@1|root,COG2864@2|Bacteria,1MXFQ@1224|Proteobacteria,1RP1B@1236|Gammaproteobacteria,1XSFF@135623|Vibrionales 135623|Vibrionales C COG2864 Cytochrome b subunit of formate dehydrogenase fdnI - - ko:K00127 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001 - - - Ni_hydr_CYTB k141_16255_4 1116375.VEJY3_07245 3.43e-85 252.0 2AZUZ@1|root,31S4B@2|Bacteria,1QJXC@1224|Proteobacteria,1THZE@1236|Gammaproteobacteria,1XXZV@135623|Vibrionales 135623|Vibrionales - - VV1697 - - - - - - - - - - - - k141_16255_5 1116375.VEJY3_07270 1.57e-278 763.0 COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,1RMKD@1236|Gammaproteobacteria,1XSE7@135623|Vibrionales 135623|Vibrionales P ammonium transporter - - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - Ammonium_transp k141_16255_6 870967.VIS19158_08097 1.84e-19 80.1 2AX0D@1|root,31NYE@2|Bacteria,1QKMS@1224|Proteobacteria,1TIS9@1236|Gammaproteobacteria,1XZJI@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_15040_1 1453501.JELR01000001_gene3210 1.18e-152 437.0 COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,1RMJF@1236|Gammaproteobacteria,4647M@72275|Alteromonadaceae 1236|Gammaproteobacteria D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP mrp GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K03593 - - - - ko00000,ko03029,ko03036 - - - FeS_assembly_P,ParA k141_14198_2 218284.CCDN010000002_gene2838 2.77e-101 306.0 COG0277@1|root,COG0277@2|Bacteria,1TPBC@1239|Firmicutes,4H9UU@91061|Bacilli,1ZCQN@1386|Bacillus 91061|Bacilli C Glycolate oxidase subunit glcD - 1.1.3.15 ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001,ko01000 - - iYO844.BSU28680 FAD-oxidase_C,FAD_binding_4 k141_27301_2 218284.CCDN010000002_gene2032 4.12e-35 120.0 COG4895@1|root,COG4895@2|Bacteria,1VEG3@1239|Firmicutes,4HNJA@91061|Bacilli,1ZIX5@1386|Bacillus 91061|Bacilli S Uncharacterized conserved protein (DUF2196) ywbE - - - - - - - - - - - DUF2196 k141_25937_1 1294265.JCM21738_2259 1.65e-169 478.0 28NSI@1|root,2ZB4U@2|Bacteria,1UZ00@1239|Firmicutes,4HDBT@91061|Bacilli,1ZDNP@1386|Bacillus 91061|Bacilli - - ytlQ - - - - - - - - - - - NERD k141_20927_2 1121085.AUCI01000004_gene1831 2.85e-36 132.0 COG2323@1|root,COG2323@2|Bacteria,1TX6U@1239|Firmicutes,4HEB2@91061|Bacilli,1ZQ03@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF421) - - - - - - - - - - - - DUF421 k141_30333_1 1294265.JCM21738_3130 6.84e-169 473.0 COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,4HA6M@91061|Bacilli,1ZB9G@1386|Bacillus 91061|Bacilli J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family yefA GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070041,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.190 ko:K03215 - - - - ko00000,ko01000,ko03009 - - - TRAM,tRNA_U5-meth_tr k141_37526_1 246200.SPO2030 2.07e-40 136.0 COG2076@1|root,COG2076@2|Bacteria,1MZ54@1224|Proteobacteria,2UBXR@28211|Alphaproteobacteria,4NCHT@97050|Ruegeria 28211|Alphaproteobacteria P Small Multidrug Resistance protein qacE - - ko:K03297 - - - - ko00000,ko02000 2.A.7.1 - - Multi_Drug_Res k141_18885_2 234267.Acid_4280 3.45e-97 303.0 COG3503@1|root,COG3503@2|Bacteria,3Y6EK@57723|Acidobacteria 57723|Acidobacteria S Protein of unknown function (DUF1624) - - - - - - - - - - - - DUF1624 k141_18885_3 1042377.AFPJ01000030_gene436 8.53e-138 415.0 COG1629@1|root,COG4771@2|Bacteria,1MUNK@1224|Proteobacteria,1RN9S@1236|Gammaproteobacteria,464ZY@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_35388_1 1453501.JELR01000005_gene1610 1.58e-145 420.0 COG3550@1|root,COG3550@2|Bacteria,1N458@1224|Proteobacteria,1RMP7@1236|Gammaproteobacteria,4645K@72275|Alteromonadaceae 1236|Gammaproteobacteria S HipA-like C-terminal domain - - 2.7.11.1 ko:K07154 - - - - ko00000,ko01000,ko01001,ko02048 - - - Couple_hipA,HipA_C k141_7930_1 1078085.HMPREF1210_00665 8.69e-75 252.0 COG1409@1|root,COG4632@1|root,COG1409@2|Bacteria,COG4632@2|Bacteria,1UWQ2@1239|Firmicutes,4I2G2@91061|Bacilli,26G7J@186818|Planococcaceae 91061|Bacilli G Purple acid Phosphatase, N-terminal domain - - - - - - - - - - - - Metallophos,Pur_ac_phosph_N k141_29301_1 218284.CCDN010000008_gene4211 3.4e-62 191.0 COG0526@1|root,COG0526@2|Bacteria,1VAS6@1239|Firmicutes,4HKGM@91061|Bacilli,1ZHAS@1386|Bacillus 91061|Bacilli CO Thioredoxin ytpP GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - - - - - - - - - - Thioredoxin k141_3135_1 218284.CCDN010000002_gene2248 5.27e-158 457.0 2BW99@1|root,2Z7PD@2|Bacteria,1TQFA@1239|Firmicutes,4HC1J@91061|Bacilli,1ZC3Q@1386|Bacillus 91061|Bacilli S Psort location CytoplasmicMembrane, score XK27_11280 - - - - - - - - - - - - k141_18886_1 1294265.JCM21738_1239 6.64e-87 259.0 COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,4HBW0@91061|Bacilli,1ZCVE@1386|Bacillus 91061|Bacilli I Enoyl-CoA hydratase/isomerase paaF - 4.2.1.17 ko:K01692 ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212 M00032,M00087 R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093 RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 k141_19901_4 1517681.HW45_22530 5.39e-62 205.0 2DGTY@1|root,2ZX9W@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k141_22284_1 1453501.JELR01000002_gene825 1.22e-24 102.0 COG3866@1|root,COG3866@2|Bacteria,1QPFF@1224|Proteobacteria,1RQEM@1236|Gammaproteobacteria,465CX@72275|Alteromonadaceae 1236|Gammaproteobacteria G Amb_all pel1C - - - - - - - - - - - CBM_35,CBM_5_12_2,CBM_6,Pec_lyase_C,RicinB_lectin_2 k141_16256_2 1453501.JELR01000002_gene1004 6.55e-83 259.0 COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,1RMB9@1236|Gammaproteobacteria,464ZX@72275|Alteromonadaceae 1236|Gammaproteobacteria O ATPase with chaperone activity comM GO:0003674,GO:0003824,GO:0004176,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0042623,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - ko:K07391 - - - - ko00000 - - - ChlI,Mg_chelatase,Mg_chelatase_C k141_29302_2 218284.CCDN010000006_gene3503 1.01e-89 271.0 COG1135@1|root,COG1135@2|Bacteria,1TPPN@1239|Firmicutes,4H9VX@91061|Bacilli,1ZAZX@1386|Bacillus 91061|Bacilli P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system metN GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0008150,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085 - ko:K02071 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - iYO844.BSU32750 ABC_tran,NIL k141_7931_2 1294265.JCM21738_4749 1.44e-07 50.1 29SEG@1|root,30DJ8@2|Bacteria,1UBCJ@1239|Firmicutes,4IMRD@91061|Bacilli,1ZKP1@1386|Bacillus 91061|Bacilli S Spo0E like sporulation regulatory protein - - - ko:K06376 - - - - ko00000 - - - SpoOE-like k141_35389_1 1523503.JPMY01000023_gene1030 1.24e-90 285.0 COG2304@1|root,COG2304@2|Bacteria,1MUTS@1224|Proteobacteria,1RQPC@1236|Gammaproteobacteria 1236|Gammaproteobacteria S von willebrand factor, type A yfbK - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - DUF3520,VWA,vWF_A k141_9305_1 42565.FP66_02740 8.13e-07 49.3 COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,1RMBF@1236|Gammaproteobacteria,1XHQ9@135619|Oceanospirillales 135619|Oceanospirillales M heptosyltransferase waaF - - ko:K02843 ko00540,ko01100,map00540,map01100 M00080 - - ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT9 - Glyco_transf_9 k141_9305_2 42565.FP66_02735 1.97e-162 457.0 COG0451@1|root,COG0451@2|Bacteria,1MVE4@1224|Proteobacteria,1RP2S@1236|Gammaproteobacteria,1XHT1@135619|Oceanospirillales 135619|Oceanospirillales GM Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose hldD - 5.1.3.20 ko:K03274 ko00540,ko01100,map00540,map01100 M00064 R05176 RC01291 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Epimerase k141_27950_1 218284.CCDN010000005_gene3242 1.13e-112 336.0 COG1233@1|root,COG1233@2|Bacteria,1TRN1@1239|Firmicutes,4HA5W@91061|Bacilli,1ZDED@1386|Bacillus 91061|Bacilli Q Flavin containing amine oxidoreductase - - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 ko:K10027 ko00906,ko01100,ko01110,map00906,map01100,map01110 - R04787,R04798,R04800,R09691,R09692 RC01214,RC02088,RC02605 ko00000,ko00001,ko01000 - - - Amino_oxidase k141_16257_1 543632.JOJL01000039_gene1611 7.53e-40 145.0 COG0520@1|root,COG0520@2|Bacteria,2GJA4@201174|Actinobacteria,4DC2F@85008|Micromonosporales 201174|Actinobacteria E aminotransferase class V - - - - - - - - - - - - Aminotran_5 k141_10428_1 218284.CCDN010000002_gene2091 1.05e-79 249.0 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli,1ZAY9@1386|Bacillus 91061|Bacilli C Belongs to the aldehyde dehydrogenase family - - 1.2.1.3,1.2.1.8 ko:K00128,ko:K00130 ko00010,ko00053,ko00071,ko00260,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00260,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135,M00555 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02565,R02566,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_10428_2 218284.CCDN010000002_gene2092 2.88e-84 255.0 COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,4HA59@91061|Bacilli,1ZB8X@1386|Bacillus 91061|Bacilli I 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain hbd - 1.1.1.157 ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 - R01976,R05576,R06941 RC00029,RC00117 ko00000,ko00001,ko01000 - - - 3HCDH,3HCDH_N k141_14225_2 1453501.JELR01000001_gene3105 1.76e-190 534.0 COG2141@1|root,COG2141@2|Bacteria,1MVF0@1224|Proteobacteria,1RMCE@1236|Gammaproteobacteria,465D0@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases yhbW GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - - - - - - - - - - Bac_luciferase k141_14225_4 1279017.AQYJ01000024_gene896 1.26e-99 293.0 COG0225@1|root,COG0225@2|Bacteria,1R33Z@1224|Proteobacteria,1T62V@1236|Gammaproteobacteria,46DFA@72275|Alteromonadaceae 1236|Gammaproteobacteria O Peptide methionine sulfoxide reductase msrA2 - 1.8.4.11 ko:K07304 - - - - ko00000,ko01000 - - - PMSR k141_14225_5 686578.AFFX01000005_gene4338 1.43e-195 551.0 COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,1RMVU@1236|Gammaproteobacteria 1236|Gammaproteobacteria C alcohol dehydrogenase - - 1.1.1.1 ko:K00001,ko:K00100 ko00010,ko00071,ko00350,ko00625,ko00626,ko00650,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00650,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R03544,R03545,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - Fe-ADH k141_14225_6 1001585.MDS_0763 9.03e-251 697.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,1YF1V@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria C belongs to the aldehyde dehydrogenase family - - - - - - - - - - - - Aldedh k141_6895_1 171693.BN988_02594 4.59e-67 217.0 COG0441@1|root,COG0441@2|Bacteria,1UHT4@1239|Firmicutes,4IS8T@91061|Bacilli,23IQG@182709|Oceanobacillus 91061|Bacilli J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) proS - 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,ProRS-C_1,tRNA-synt_2b k141_32840_2 218284.CCDN010000001_gene1289 4.43e-85 254.0 COG0500@1|root,COG2226@2|Bacteria,1V9BF@1239|Firmicutes,4HK9K@91061|Bacilli,1ZGGF@1386|Bacillus 91061|Bacilli Q Methyltransferase domain ydaC - - - - - - - - - - - Methyltransf_11,Methyltransf_25 k141_37546_1 28152.DJ57_444 9.83e-45 166.0 COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,1RMW9@1236|Gammaproteobacteria,41FUT@629|Yersinia 1236|Gammaproteobacteria G Glycosyl hydrolase 36 superfamily, catalytic domain chbP - 2.4.1.20,2.4.1.280 ko:K00702,ko:K13688,ko:K18675 ko00500,ko00520,ko01100,map00500,map00520,map01100 - R00952,R09942 RC00049 ko00000,ko00001,ko01000,ko01003 - GH94,GT36,GT84 - Glyco_hydro_36,Glyco_transf_36,Glycoamylase k141_30338_1 757424.Hsero_2411 2.79e-11 65.5 COG4977@1|root,COG4977@2|Bacteria,1QV1S@1224|Proteobacteria,2WI4I@28216|Betaproteobacteria 28216|Betaproteobacteria K Cupin - - - - - - - - - - - - Cupin_6,HTH_18 k141_14226_1 218284.CCDN010000001_gene52 1.91e-103 323.0 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4H9S5@91061|Bacilli,1ZCDJ@1386|Bacillus 91061|Bacilli P COG0474 Cation transport ATPase yloB GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - iYO844.BSU15650 Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase k141_18929_2 1307436.PBF_03640 6.89e-142 412.0 COG1306@1|root,COG1306@2|Bacteria,1TQZV@1239|Firmicutes,4HAPK@91061|Bacilli,1ZCIN@1386|Bacillus 91061|Bacilli S Putative glycosyl hydrolase domain - - - - - - - - - - - - DUF4015 k141_27967_1 218284.CCDN010000001_gene30 2.29e-16 75.1 COG1349@1|root,COG1349@2|Bacteria,1V3MJ@1239|Firmicutes,4HHFC@91061|Bacilli,1ZAV1@1386|Bacillus 91061|Bacilli K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism fapR - - - - - - - - - - - 4HBT,HTH_DeoR,MaoC_dehydratas k141_27967_2 218284.CCDN010000001_gene31 1.6e-67 222.0 COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,4HAWN@91061|Bacilli,1ZC17@1386|Bacillus 91061|Bacilli L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) recG GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecG_wedge k141_11692_1 218284.CCDN010000005_gene3372 1e-106 314.0 COG0388@1|root,COG0388@2|Bacteria,1TQDK@1239|Firmicutes,4HC44@91061|Bacilli,1ZB5Z@1386|Bacillus 91061|Bacilli S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase mtnU - 3.5.1.3 ko:K13566 ko00250,map00250 - R00269,R00348 RC00010 ko00000,ko00001,ko01000 - - - CN_hydrolase k141_27337_1 458817.Shal_2185 2.62e-150 447.0 COG4694@1|root,COG4694@2|Bacteria,1PRHR@1224|Proteobacteria,1RWYP@1236|Gammaproteobacteria,2QEEH@267890|Shewanellaceae 1236|Gammaproteobacteria S AAA domain - - - - - - - - - - - - AAA_13 k141_29334_1 218284.CCDN010000002_gene2001 1.71e-41 145.0 COG4851@1|root,COG4851@2|Bacteria,1TSYE@1239|Firmicutes,4HBI8@91061|Bacilli,1ZBGV@1386|Bacillus 91061|Bacilli S COG4851 Protein involved in sex pheromone biosynthesis camS - - - - - - - - - - - CamS k141_29334_2 743719.PaelaDRAFT_4551 2.55e-10 58.9 2EECF@1|root,3386Q@2|Bacteria,1VIE5@1239|Firmicutes,4HPWH@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF3949) - - - - - - - - - - - - DUF3949 k141_36339_1 1117379.BABA_06481 1.37e-172 491.0 COG2252@1|root,COG2252@2|Bacteria,1TQC6@1239|Firmicutes,4HANG@91061|Bacilli,1ZDJJ@1386|Bacillus 91061|Bacilli S permease pbuO - - ko:K06901 - - - - ko00000,ko02000 2.A.1.40 - - Xan_ur_permease k141_36339_2 1294265.JCM21738_1995 5.6e-47 153.0 COG0167@1|root,COG0167@2|Bacteria,1TRFE@1239|Firmicutes,4HDHX@91061|Bacilli,1ZC3E@1386|Bacillus 91061|Bacilli F Dihydroorotate dehydrogenase - - 1.3.5.2 ko:K00254 ko00240,ko01100,map00240,map01100 M00051 R01868 RC00051 ko00000,ko00001,ko00002,ko01000 - - - DHO_dh k141_6897_1 1137799.GZ78_00595 3.13e-24 101.0 COG3666@1|root,COG3666@2|Bacteria,1Q0SK@1224|Proteobacteria,1SQNW@1236|Gammaproteobacteria,1XPP8@135619|Oceanospirillales 135619|Oceanospirillales L Transposase DDE domain - - - - - - - - - - - - DDE_Tnp_1_6,DUF772 k141_22309_1 935836.JAEL01000004_gene2484 1.49e-88 275.0 COG2271@1|root,COG2271@2|Bacteria,1TRHT@1239|Firmicutes,4HDG8@91061|Bacilli,1ZCIM@1386|Bacillus 91061|Bacilli G COG0477 Permeases of the major facilitator superfamily ybfB GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - MFS_1 k141_22309_3 218284.CCDN010000001_gene1547 1.23e-87 271.0 COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,4ISRZ@91061|Bacilli,1ZQ9G@1386|Bacillus 91061|Bacilli S Domain of unknown function DUF21 - - - - - - - - - - - - CBS,CorC_HlyC,DUF21 k141_19918_1 1121948.AUAC01000003_gene2323 1.28e-71 234.0 COG1506@1|root,COG1506@2|Bacteria,1MUJ3@1224|Proteobacteria,2U3RR@28211|Alphaproteobacteria,43X69@69657|Hyphomonadaceae 28211|Alphaproteobacteria E Prolyl oligopeptidase family - - - - - - - - - - - - Peptidase_S9 k141_14228_1 1280944.HY17_16715 1.94e-30 120.0 COG4962@1|root,COG4962@2|Bacteria,1R7EN@1224|Proteobacteria,2TTUS@28211|Alphaproteobacteria,43WCT@69657|Hyphomonadaceae 28211|Alphaproteobacteria U Conjugal transfer protein - - - ko:K20527 ko02024,map02024 - - - ko00000,ko00001,ko02044 3.A.7.4 - - T2SSE k141_27338_1 1134474.O59_000965 8.46e-21 85.9 COG2351@1|root,COG2351@2|Bacteria,1RH84@1224|Proteobacteria,1SC8E@1236|Gammaproteobacteria,1FIDH@10|Cellvibrio 1236|Gammaproteobacteria S HIUase/Transthyretin family uraH - 3.5.2.17 ko:K07127 ko00230,ko01100,ko01120,map00230,map01100,map01120 M00546 R06601 RC03393 ko00000,ko00001,ko00002,ko01000,ko02000 9.B.35.1.2,9.B.35.2 - - Transthyretin k141_27338_2 498211.CJA_0551 6.47e-24 102.0 COG0402@1|root,COG0402@2|Bacteria,1MUPT@1224|Proteobacteria,1SYCI@1236|Gammaproteobacteria,1FHTU@10|Cellvibrio 1236|Gammaproteobacteria F Amidohydrolase family guaD - 3.5.4.3 ko:K01487 ko00230,ko01100,map00230,map01100 - R01676 RC00204 ko00000,ko00001,ko01000 - - - Amidohydro_1 k141_34150_1 1121087.AUCK01000022_gene1854 4.61e-58 196.0 COG0477@1|root,COG2814@2|Bacteria,1TPRN@1239|Firmicutes,4H9VV@91061|Bacilli,1ZAXQ@1386|Bacillus 91061|Bacilli EGP the major facilitator superfamily - - - - - - - - - - - - MFS_1 k141_10429_1 323850.Shew_2868 4.38e-37 138.0 COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,1RPHJ@1236|Gammaproteobacteria,2QDQD@267890|Shewanellaceae 1236|Gammaproteobacteria C PFAM acyl-CoA dehydrogenase domain protein bcd - 1.3.8.1 ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 - R01175,R01178,R02661,R03172,R04751 RC00052,RC00068,RC00076,RC00120,RC00148 ko00000,ko00001,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N k141_10429_2 1453501.JELR01000001_gene1868 1.14e-19 88.2 COG0707@1|root,COG0707@2|Bacteria,1MWQP@1224|Proteobacteria,1T31H@1236|Gammaproteobacteria,46D2Z@72275|Alteromonadaceae 1236|Gammaproteobacteria M Glycosyl transferase family 1 - - - - - - - - - - - - Glyco_trans_1_3 k141_32842_1 1279017.AQYJ01000020_gene1336 3.87e-57 180.0 2D8VC@1|root,32TS1@2|Bacteria,1MZWT@1224|Proteobacteria,1SQ4N@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_32842_2 1279017.AQYJ01000020_gene1333 4.25e-05 44.7 COG2334@1|root,COG2334@2|Bacteria,1MU2Q@1224|Proteobacteria,1RNHI@1236|Gammaproteobacteria,464EM@72275|Alteromonadaceae 1236|Gammaproteobacteria F A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response srkA GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0071704,GO:0140096,GO:1901564 - - - - - - - - - - APH k141_3154_2 1131730.BAVI_03049 3.65e-99 298.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4HASW@91061|Bacilli,1ZB29@1386|Bacillus 91061|Bacilli I Belongs to the thiolase family - - 2.3.1.16,2.3.1.9 ko:K00626,ko:K00632 ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00087,M00088,M00095,M00113,M00373,M00374,M00375 R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095 RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N k141_18931_1 218284.CCDN010000001_gene1017 1.53e-37 133.0 COG4975@1|root,COG4975@2|Bacteria,1TQBN@1239|Firmicutes,4HAVH@91061|Bacilli,1ZE1R@1386|Bacillus 91061|Bacilli U Glucose uptake glcU - - ko:K05340 - - - - ko00000,ko02000 2.A.7.5 - - Sugar_transport k141_18931_2 218284.CCDN010000001_gene1018 3.38e-76 234.0 COG1028@1|root,COG1028@2|Bacteria,1TR5M@1239|Firmicutes,4HCD2@91061|Bacilli,1ZD11@1386|Bacillus 91061|Bacilli IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) gdh - 1.1.1.47 ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 - R01520,R01521 RC00066 ko00000,ko00001,ko01000 - - - adh_short_C2 k141_22310_1 1120950.KB892709_gene4052 3.66e-42 158.0 COG1529@1|root,COG2080@1|root,COG1529@2|Bacteria,COG2080@2|Bacteria,2GIY7@201174|Actinobacteria,4DP7H@85009|Propionibacteriales 201174|Actinobacteria C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - 1.3.99.16 ko:K07303 - - - - ko00000,ko01000 - - - Ald_Xan_dh_C2,Fer2,Fer2_2 k141_27339_1 935836.JAEL01000080_gene96 1.21e-73 237.0 COG3069@1|root,COG3069@2|Bacteria,1TPZ6@1239|Firmicutes,4HEQW@91061|Bacilli,1ZDXH@1386|Bacillus 91061|Bacilli C C4-dicarboxylate transmembrane transporter activity - - - - - - - - - - - - - k141_14229_2 562743.JH976444_gene585 1.33e-20 92.0 COG1668@1|root,COG1668@2|Bacteria,1UIRA@1239|Firmicutes,4ISR6@91061|Bacilli 91061|Bacilli CP ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_2,ABC2_membrane_3 k141_9313_1 472759.Nhal_2242 4.92e-76 241.0 COG0055@1|root,COG0055@2|Bacteria,1N6UZ@1224|Proteobacteria,1RNQW@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits - - 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_N k141_9313_2 1395571.TMS3_0109405 1.73e-162 461.0 COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,1RS05@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Belongs to the pirin family - - - ko:K06911 - - - - ko00000 - - - Pirin,Pirin_C k141_9313_3 1279017.AQYJ01000029_gene3850 2.42e-166 473.0 COG0429@1|root,COG0429@2|Bacteria,1MWV1@1224|Proteobacteria,1RN39@1236|Gammaproteobacteria,46554@72275|Alteromonadaceae 1236|Gammaproteobacteria S hydrolase of the alpha beta-hydrolase fold yheT GO:0003674,GO:0003824,GO:0006629,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0044237,GO:0044238,GO:0044255,GO:0050526,GO:0052689,GO:0071704 - ko:K07019 - - - - ko00000 - - - Abhydrolase_1 k141_15190_1 1116375.VEJY3_01785 4.63e-181 509.0 2DMB3@1|root,32FBS@2|Bacteria,1RM3S@1224|Proteobacteria,1S8Q4@1236|Gammaproteobacteria,1Y2AW@135623|Vibrionales 135623|Vibrionales M Domain of unknown function (DUF4382) - - - - - - - - - - - - DUF4382 k141_13074_1 196162.Noca_3746 3.82e-72 244.0 COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria,4DTJX@85009|Propionibacteriales 201174|Actinobacteria P Heavy-metal-associated domain - - 3.6.3.3,3.6.3.4,3.6.3.5,3.6.3.54 ko:K01533,ko:K01534,ko:K12954,ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3,3.A.3.5,3.A.3.6 - - E1-E2_ATPase,HMA,Hydrolase k141_31624_1 997296.PB1_08327 3.14e-52 178.0 29H5Q@1|root,30439@2|Bacteria,1V63Q@1239|Firmicutes,4HHR2@91061|Bacilli,1ZE9T@1386|Bacillus 91061|Bacilli S Nuclease-related domain - - - - - - - - - - - - NERD k141_33078_1 204669.Acid345_0581 3.21e-25 101.0 COG1974@1|root,COG1974@2|Bacteria,3Y47Z@57723|Acidobacteria,2JIJ3@204432|Acidobacteriia 204432|Acidobacteriia K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair lexA - 3.4.21.88 ko:K01356 - M00729 - - ko00000,ko00002,ko01000,ko01002,ko03400 - - - LexA_DNA_bind,Peptidase_S24 k141_33078_2 511062.GU3_12580 1.15e-11 66.6 COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,1RNXV@1236|Gammaproteobacteria,1Y3M8@135624|Aeromonadales 135624|Aeromonadales F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) trpD - 2.4.2.18 ko:K00766 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R01073 RC00440 ko00000,ko00001,ko00002,ko01000 - - - Glycos_trans_3N,Glycos_transf_3 k141_2124_1 1042377.AFPJ01000025_gene621 1.59e-33 121.0 COG1853@1|root,COG1853@2|Bacteria,1RDFM@1224|Proteobacteria,1RTF9@1236|Gammaproteobacteria,466VM@72275|Alteromonadaceae 1236|Gammaproteobacteria S Flavin reductase like domain - - - - - - - - - - - - Flavin_Reduct k141_2124_2 1307437.J139_15637 3.12e-36 127.0 COG3011@1|root,COG3011@2|Bacteria,1N08P@1224|Proteobacteria,1S8S3@1236|Gammaproteobacteria,2Q2JB@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - DUF393 k141_21147_1 1347087.CBYO010000022_gene3910 5.91e-42 149.0 COG2311@1|root,COG2311@2|Bacteria,1TQNS@1239|Firmicutes,4HCR3@91061|Bacilli 91061|Bacilli P membrane - - - ko:K07148 - - - - ko00000 - - - DUF418 k141_24923_1 743719.PaelaDRAFT_3609 2.72e-133 390.0 COG0370@1|root,COG0370@2|Bacteria,1TP7E@1239|Firmicutes,4HDFJ@91061|Bacilli,26UJY@186822|Paenibacillaceae 91061|Bacilli P Iron transporter FeoB - - - ko:K04759 - - - - ko00000,ko02000 9.A.8.1 - - FeoB_C,FeoB_N,Gate k141_20196_1 218284.CCDN010000008_gene4087 9.65e-56 180.0 COG2188@1|root,COG2188@2|Bacteria,1TRF6@1239|Firmicutes,4HDCX@91061|Bacilli,1ZATF@1386|Bacillus 91061|Bacilli K transcriptional treR - - ko:K03486 - - - - ko00000,ko03000 - - - GntR,UTRA k141_37761_1 218284.CCDN010000002_gene2079 6.12e-111 322.0 COG1802@1|root,COG1802@2|Bacteria,1TSV2@1239|Firmicutes,4HM0G@91061|Bacilli,1ZCJX@1386|Bacillus 91061|Bacilli K FCD - - - - - - - - - - - - FCD,GntR k141_36458_1 1116375.VEJY3_07000 0.0 1776.0 COG0443@1|root,COG0443@2|Bacteria,1MXX7@1224|Proteobacteria,1RP0D@1236|Gammaproteobacteria,1XTBY@135623|Vibrionales 135623|Vibrionales O Belongs to the heat shock protein 70 family - - - - - - - - - - - - DUF3731,HSP70 k141_36458_2 1116375.VEJY3_07005 0.0 1216.0 COG0443@1|root,COG0443@2|Bacteria,1MXX7@1224|Proteobacteria,1RQ12@1236|Gammaproteobacteria,1XTFW@135623|Vibrionales 135623|Vibrionales O Belongs to the heat shock protein 70 family - - - - - - - - - - - - HSP70 k141_36458_3 1116375.VEJY3_07010 1.04e-114 332.0 2CNUX@1|root,32SHU@2|Bacteria,1REYT@1224|Proteobacteria,1S2ZX@1236|Gammaproteobacteria,1XSGJ@135623|Vibrionales 135623|Vibrionales S Domain of unknown function (DUF2760) VV12320 - - - - - - - - - - - DUF2760 k141_36458_5 1219076.N646_0505 3.3e-124 353.0 COG5018@1|root,COG5018@2|Bacteria,1NBZ1@1224|Proteobacteria,1T1XQ@1236|Gammaproteobacteria,1XUGB@135623|Vibrionales 135623|Vibrionales L Exonuclease - - - - - - - - - - - - RNase_T k141_36458_6 1116375.VEJY3_07020 1.99e-81 243.0 COG4103@1|root,COG4103@2|Bacteria,1N6YZ@1224|Proteobacteria,1SD1K@1236|Gammaproteobacteria,1XXJC@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria - - - - - - - - - - - - TerB k141_36458_7 1116375.VEJY3_07025 0.0 1151.0 COG3540@1|root,COG3540@2|Bacteria,1MW0G@1224|Proteobacteria,1RP8H@1236|Gammaproteobacteria,1XV9E@135623|Vibrionales 135623|Vibrionales P Isoleucyl-tRNA synthetase - - - - - - - - - - - - PhoD k141_36458_8 223926.28806436 1.93e-61 190.0 2B24R@1|root,31UMW@2|Bacteria,1QSHI@1224|Proteobacteria,1THZZ@1236|Gammaproteobacteria,1XY1S@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_36458_9 223926.28806437 8.46e-272 748.0 COG3713@1|root,COG3713@2|Bacteria,1MXXC@1224|Proteobacteria,1RYNJ@1236|Gammaproteobacteria,1XU8E@135623|Vibrionales 135623|Vibrionales M MltA-interacting protein MipA - - - ko:K07274 - - - - ko00000,ko02000 9.B.99.1 - - MipA k141_36458_10 1116375.VEJY3_07035 1.38e-62 196.0 2AXG4@1|root,31PFP@2|Bacteria,1QM5H@1224|Proteobacteria,1TJDC@1236|Gammaproteobacteria,1Y125@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_36458_12 1191299.AJYX01000098_gene695 9.04e-121 349.0 COG4912@1|root,COG4912@2|Bacteria,1QJE3@1224|Proteobacteria,1THDC@1236|Gammaproteobacteria,1XX53@135623|Vibrionales 135623|Vibrionales L DNA alkylation repair enzyme - - - - - - - - - - - - DNA_alkylation k141_16531_1 1294265.JCM21738_5161 3.19e-238 659.0 COG1292@1|root,COG1292@2|Bacteria,1TRS6@1239|Firmicutes,4HA7U@91061|Bacilli,1ZBRN@1386|Bacillus 91061|Bacilli M Belongs to the BCCT transporter (TC 2.A.15) family - - - ko:K05020 - - - - ko00000,ko02000 2.A.15.1.1,2.A.15.1.11 - - BCCT k141_8034_1 641524.ADICYQ_2371 6.06e-111 341.0 COG0376@1|root,COG0376@2|Bacteria,4NG30@976|Bacteroidetes 976|Bacteroidetes P Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity katG - 1.11.1.21 ko:K03782 ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110 - R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906 RC00034,RC00213,RC00767,RC02141 ko00000,ko00001,ko01000 - - - peroxidase k141_10614_1 1294265.JCM21738_1423 9.14e-102 296.0 COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,4HA2S@91061|Bacilli,1ZAUS@1386|Bacillus 91061|Bacilli P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components dppB GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0022857,GO:0051179,GO:0051234,GO:0055085 - ko:K16200 ko02010,map02010 M00566 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.2 - iYO844.BSU12930 BPD_transp_1 k141_10614_2 1294265.JCM21738_1422 1.78e-26 103.0 COG2362@1|root,COG2362@2|Bacteria,1TSUZ@1239|Firmicutes,4HC5R@91061|Bacilli,1ZC41@1386|Bacillus 91061|Bacilli E D-aminopeptidase dppA - - ko:K16203 - - - - ko00000,ko01000,ko01002 3.A.1.5.2 - iYO844.BSU12920 Peptidase_M55 k141_16532_1 698769.JFBD01000024_gene1884 5.45e-56 179.0 arCOG05874@1|root,2ZJ01@2|Bacteria,1V450@1239|Firmicutes,4HFPA@91061|Bacilli,4C6TS@84406|Virgibacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_33119_1 1453501.JELR01000001_gene2494 5.36e-244 701.0 COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,1T4K6@1236|Gammaproteobacteria,46DC0@72275|Alteromonadaceae 1236|Gammaproteobacteria KLT Sulfatase-modifying factor enzyme 1 ppkA - 2.7.11.1 ko:K11912 ko02025,ko03070,map02025,map03070 - - - ko00000,ko00001,ko01000,ko01001,ko02044 - - - FGE-sulfatase,PEGA,Pkinase k141_33119_2 1279017.AQYJ01000025_gene751 1.26e-134 391.0 COG0631@1|root,COG0631@2|Bacteria,1R7UF@1224|Proteobacteria,1RQUV@1236|Gammaproteobacteria,46746@72275|Alteromonadaceae 1236|Gammaproteobacteria T Serine/threonine phosphatases, family 2C, catalytic domain - - 3.1.3.16 ko:K20074 - - - - ko00000,ko01000,ko01009 - - - PP2C,PP2C_2 k141_33119_3 1042377.AFPJ01000007_gene1923 1.14e-121 357.0 COG1716@1|root,COG1716@2|Bacteria,1RAA4@1224|Proteobacteria,1S3GK@1236|Gammaproteobacteria,4687T@72275|Alteromonadaceae 1236|Gammaproteobacteria T Forkhead associated domain - - - - - - - - - - - - FHA,Yop-YscD_cpl k141_33119_4 1279017.AQYJ01000025_gene749 1.12e-35 122.0 COG0526@1|root,33ARA@2|Bacteria 2|Bacteria CO COG0526, thiol-disulfide isomerase and thioredoxins - - - - - - - - - - - - DUF836 k141_33119_5 1453501.JELR01000001_gene2490 1.6e-18 84.3 COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,1RMS8@1236|Gammaproteobacteria,4657M@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) slt GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009274,GO:0016740,GO:0016757,GO:0030203,GO:0030288,GO:0030312,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - ko:K08309 - - - - ko00000,ko01000,ko01011 - GH23 iETEC_1333.ETEC_4747,iPC815.YPO0452 SLT,SLT_L k141_15224_1 218284.CCDN010000005_gene3208 4.65e-126 365.0 COG0679@1|root,COG0679@2|Bacteria,1UEYG@1239|Firmicutes,4HD45@91061|Bacilli,1ZD15@1386|Bacillus 91061|Bacilli S Membrane transport protein - - - ko:K07088 - - - - ko00000 - - - Mem_trans k141_17690_2 555778.Hneap_1375 1.14e-173 492.0 COG1064@1|root,COG1064@2|Bacteria,1MUTT@1224|Proteobacteria,1RN4D@1236|Gammaproteobacteria,1WXPM@135613|Chromatiales 135613|Chromatiales S PFAM Alcohol dehydrogenase - - - ko:K12957,ko:K13979 - - - - ko00000,ko01000 - - - ADH_N,ADH_zinc_N k141_10615_1 1453501.JELR01000001_gene3139 3.9e-44 143.0 COG2040@1|root,COG2040@2|Bacteria,1N7A3@1224|Proteobacteria,1SCA1@1236|Gammaproteobacteria,468HX@72275|Alteromonadaceae 1236|Gammaproteobacteria E Protein of unknown function (DUF2789) XAC1354 - - - - - - - - - - - DUF2789 k141_29665_1 997296.PB1_08127 9.65e-61 192.0 COG0356@1|root,COG0356@2|Bacteria,1TQIT@1239|Firmicutes,4H9NV@91061|Bacilli,1ZB02@1386|Bacillus 91061|Bacilli C it plays a direct role in the translocation of protons across the membrane atpB GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 - - ATP-synt_A k141_29665_2 1294265.JCM21738_3685 2.11e-64 197.0 2E2UM@1|root,32XWN@2|Bacteria,1VDFF@1239|Firmicutes,4HJ3R@91061|Bacilli,1ZH6N@1386|Bacillus 91061|Bacilli S ATP synthase I chain atpI - - ko:K02116 - - - - ko00000,ko00194 3.A.2.1 - - ATP-synt_I k141_4600_3 469616.FMAG_01752 1.04e-19 86.3 COG3108@1|root,COG3108@2|Bacteria,37C8S@32066|Fusobacteria 32066|Fusobacteria S Peptidase M15 - - - - - - - - - - - - - k141_4600_4 1540098.A0A0A0RQD4_9CAUD 3.28e-19 87.8 4QB6U@10239|Viruses,4QQ2F@28883|Caudovirales,4QKMH@10699|Siphoviridae 10699|Siphoviridae S Terminase small subunit - - - - - - - - - - - - - k141_4600_5 1175654.A0A0S0MVJ7_9CAUD 9.41e-33 120.0 4QFW7@10239|Viruses,4QX0V@35237|dsDNA viruses no RNA stage,4QU0S@28883|Caudovirales,4QM9S@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k141_4600_23 1175654.A0A0S0N2K6_9CAUD 4.7e-241 697.0 4QBSJ@10239|Viruses,4QXH4@35237|dsDNA viruses no RNA stage,4QPFJ@28883|Caudovirales,4QKUK@10699|Siphoviridae 10699|Siphoviridae S DNA primase activity - - - - - - - - - - - - - k141_2180_1 1294265.JCM21738_357 7.67e-180 520.0 COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,4HA8S@91061|Bacilli,1ZBWA@1386|Bacillus 91061|Bacilli J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,IF-2,IF2_N k141_31658_1 1453501.JELR01000002_gene55 1.52e-87 288.0 COG2911@1|root,COG2911@2|Bacteria,1MUVD@1224|Proteobacteria 1224|Proteobacteria M Protein conserved in bacteria tamB - - ko:K09800 - - - - ko00000,ko02000 - - - TamB k141_10616_1 1279017.AQYJ01000027_gene1947 1.68e-20 95.5 2DP2E@1|root,3308P@2|Bacteria,1QWD2@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_36507_1 1042377.AFPJ01000016_gene121 0.0 969.0 COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,1RNA5@1236|Gammaproteobacteria,4641A@72275|Alteromonadaceae 1236|Gammaproteobacteria P Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity katG GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.11.1.21 ko:K03782 ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110 - R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906 RC00034,RC00213,RC00767,RC02141 ko00000,ko00001,ko01000 - - - peroxidase k141_36507_2 1042377.AFPJ01000032_gene2757 1.27e-61 194.0 COG1051@1|root,COG1051@2|Bacteria 2|Bacteria F GDP-mannose mannosyl hydrolase activity - - 2.1.3.15,6.4.1.2 ko:K01962,ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - NUDIX k141_8036_1 460265.Mnod_0373 2.72e-31 123.0 COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,2TSGZ@28211|Alphaproteobacteria,1JUJU@119045|Methylobacteriaceae 28211|Alphaproteobacteria L PFAM transposase IS116 IS110 IS902 family - - - - - - - - - - - - DEDD_Tnp_IS110,Transposase_20 k141_29666_1 573370.DMR_39060 4.03e-21 93.2 COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,42NBJ@68525|delta/epsilon subdivisions,2WJ52@28221|Deltaproteobacteria,2M904@213115|Desulfovibrionales 28221|Deltaproteobacteria O PFAM magnesium chelatase ChlI subunit comM - - ko:K07391 - - - - ko00000 - - - ChlI,Mg_chelatase,Mg_chelatase_C k141_33121_1 1042377.AFPJ01000036_gene1262 1.25e-49 165.0 COG2930@1|root,COG2930@2|Bacteria,1RCH3@1224|Proteobacteria,1S2SV@1236|Gammaproteobacteria,466VF@72275|Alteromonadaceae 1236|Gammaproteobacteria S Las17-binding protein actin regulator VPA0371 - - - - - - - - - - - Ysc84 k141_4601_1 1453501.JELR01000002_gene131 1.03e-115 337.0 COG2197@1|root,COG2197@2|Bacteria,1P4TD@1224|Proteobacteria,1RU35@1236|Gammaproteobacteria,466GT@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain tcsR - - - - - - - - - - - GerE,Response_reg k141_37809_1 1279017.AQYJ01000023_gene3198 5.23e-52 171.0 COG0500@1|root,COG2226@2|Bacteria,1MXDY@1224|Proteobacteria,1RMU7@1236|Gammaproteobacteria,466NC@72275|Alteromonadaceae 1236|Gammaproteobacteria Q COG0500 SAM-dependent methyltransferases rrmA GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008270,GO:0008649,GO:0008757,GO:0008989,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.187 ko:K00563 - - R07233 RC00003 ko00000,ko01000,ko03009 - - - Methyltransf_11,Methyltransf_25,Methyltransf_31 k141_37809_2 1279017.AQYJ01000023_gene3197 1.53e-283 787.0 COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,1RMD2@1236|Gammaproteobacteria,46508@72275|Alteromonadaceae 1236|Gammaproteobacteria E Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate alkJ - 1.1.99.1 ko:K00108 ko00260,ko01100,map00260,map01100 M00555 R01025 RC00087 ko00000,ko00001,ko00002,ko01000 - - - GMC_oxred_C,GMC_oxred_N k141_37809_3 1122604.JONR01000001_gene1921 3.03e-74 232.0 COG0500@1|root,COG0500@2|Bacteria,1QWS3@1224|Proteobacteria,1T4VS@1236|Gammaproteobacteria,1X6GY@135614|Xanthomonadales 135614|Xanthomonadales Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_23,Methyltransf_31 k141_10617_1 1453501.JELR01000002_gene764 1.22e-76 251.0 COG1680@1|root,COG1680@2|Bacteria,1MWHS@1224|Proteobacteria,1RRQF@1236|Gammaproteobacteria 1236|Gammaproteobacteria V COG1680 Beta-lactamase class C and other penicillin binding - - - - - - - - - - - - ASH,Beta-lactamase k141_3399_2 377629.TERTU_4592 2.16e-26 103.0 2CFV6@1|root,32RKG@2|Bacteria,1MZSJ@1224|Proteobacteria,1S9II@1236|Gammaproteobacteria,2PQCH@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria S SpoIIAA-like - - - - - - - - - - - - SpoIIAA-like k141_3399_3 1042377.AFPJ01000043_gene844 3.09e-47 167.0 COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria,464PM@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG1404 Subtilisin-like serine proteases - GO:0005575,GO:0005576 - ko:K14645 ko02024,map02024 - - - ko00000,ko00001,ko01000,ko01002,ko03110 - - - PKD,PPC,P_proprotein,Peptidase_S8 k141_17693_1 441769.ABFU01000013_gene2458 6.9e-39 141.0 COG0591@1|root,COG0591@2|Bacteria,1TPVE@1239|Firmicutes,4H9KW@91061|Bacilli,1ZB64@1386|Bacillus 91061|Bacilli E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - ko:K11928 - - - - ko00000,ko02000 2.A.21.2 - - SSF k141_34379_2 1347368.HG964403_gene4365 1.1e-09 60.1 COG1544@1|root,COG1544@2|Bacteria,1V1D5@1239|Firmicutes,4HFX9@91061|Bacilli,1ZFW8@1386|Bacillus 91061|Bacilli J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase hpf GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - ko:K05808 - - - - ko00000,ko03009 - - - Ribosom_S30AE_C,Ribosomal_S30AE k141_21199_2 1347368.HG964403_gene4718 2.57e-05 50.8 2D5MU@1|root,32TJF@2|Bacteria,1V9ZA@1239|Firmicutes,4HKVE@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - k141_15226_1 1294265.JCM21738_5070 4.08e-106 328.0 COG0507@1|root,COG0507@2|Bacteria,1TPZH@1239|Firmicutes,4HATQ@91061|Bacilli,1ZAYS@1386|Bacillus 91061|Bacilli L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity recD2 - 3.1.11.5 ko:K03581 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_30,HHH_4,HHH_5,UvrD_C_2 k141_10618_1 1294265.JCM21738_2695 4.66e-107 319.0 COG1175@1|root,COG1175@2|Bacteria,1TR2A@1239|Firmicutes,4HB8H@91061|Bacilli,1ZBHD@1386|Bacillus 91061|Bacilli P COG1175 ABC-type sugar transport systems, permease components malC GO:0003674,GO:0003824,GO:0005215,GO:0005363,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015154,GO:0015157,GO:0015399,GO:0015405,GO:0015422,GO:0015423,GO:0015766,GO:0015768,GO:0015772,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0032991,GO:0034219,GO:0042623,GO:0042626,GO:0043190,GO:0043211,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990060,GO:1990351 - ko:K15771 ko02010,map02010 M00491 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.16,3.A.1.1.2 - iYO844.BSU34150 BPD_transp_1 k141_16533_1 218284.CCDN010000005_gene3272 1.02e-11 59.3 2C7Y5@1|root,2ZW4E@2|Bacteria,1W5UC@1239|Firmicutes,4HZZW@91061|Bacilli,1ZJ0V@1386|Bacillus 91061|Bacilli S ComZ comZ - - ko:K02254 - - - - ko00000,ko02044 - - - ComZ k141_16533_2 218284.CCDN010000005_gene3273 6.86e-204 566.0 COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,4HATK@91061|Bacilli,1ZAQ1@1386|Bacillus 91061|Bacilli I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids fabH GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - iYO844.BSU11330 ACP_syn_III,ACP_syn_III_C k141_16533_3 218284.CCDN010000005_gene3274 3.59e-176 498.0 COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,4H9SD@91061|Bacilli,1ZD02@1386|Bacillus 91061|Bacilli I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP fabF - 2.3.1.179 ko:K09458,ko:K14660 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - iSB619.SA_RS04785 Ketoacyl-synt_C,ketoacyl-synt k141_17695_1 871585.BDGL_001568 3.83e-07 57.0 COG4772@1|root,COG4772@2|Bacteria,1MWDG@1224|Proteobacteria,1RQA5@1236|Gammaproteobacteria,3NKK5@468|Moraxellaceae 1236|Gammaproteobacteria P TonB dependent receptor fecA - - ko:K16091 - - - - ko00000,ko02000 1.B.14.1.14 - - Plug,STN,TonB_dep_Rec k141_29669_1 1444310.JANV01000077_gene287 7.91e-99 299.0 COG0766@1|root,COG0766@2|Bacteria,1TPAU@1239|Firmicutes,4H9KI@91061|Bacilli,1ZB89@1386|Bacillus 91061|Bacilli M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine murA - 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R00660 RC00350 ko00000,ko00001,ko01000,ko01011 - - - EPSP_synthase k141_17696_1 1117379.BABA_04284 5.98e-57 192.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,1ZBXB@1386|Bacillus 91061|Bacilli V COG1132 ABC-type multidrug transport system, ATPase and permease components mdlA - - ko:K06148,ko:K18889 ko02010,map02010 M00707 - - ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.106.13,3.A.1.106.5 - - ABC_membrane,ABC_tran k141_17696_2 1307436.PBF_14899 1.6e-10 61.2 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,1ZBIW@1386|Bacillus 91061|Bacilli V COG1132 ABC-type multidrug transport system, ATPase and permease components mdlB - - ko:K06147,ko:K18890 ko02010,map02010 M00707 - - ko00000,ko00001,ko00002,ko02000 3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran k141_4604_1 42565.FP66_05685 2.49e-18 84.0 COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,1RMZ8@1236|Gammaproteobacteria,1XI30@135619|Oceanospirillales 135619|Oceanospirillales I Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate fadB - 1.1.1.35,4.2.1.17,5.1.2.3,5.3.3.8 ko:K01825 ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212 M00032,M00087 R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R04756,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094 RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01078,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 - - - 3HCDH,3HCDH_N,ECH_1 k141_4604_2 42565.FP66_05690 9.49e-55 181.0 28IX1@1|root,2Z8V3@2|Bacteria,1N0WD@1224|Proteobacteria,1RSH6@1236|Gammaproteobacteria,1XP8A@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF2914) - - - - - - - - - - - - DUF2914 k141_2181_1 698769.JFBD01000002_gene2745 3.99e-145 431.0 2D8E6@1|root,32TR4@2|Bacteria,1VAUI@1239|Firmicutes,4HME1@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - k141_2181_2 749413.E5DV50_9VIRU 1.35e-41 148.0 4QC1Z@10239|Viruses,4QWFJ@35237|dsDNA viruses no RNA stage 10239|Viruses S Terminase-like family - - - - - - - - - - - - - k141_10620_1 1385512.N784_00280 2.89e-72 238.0 COG3290@1|root,COG3829@1|root,COG3290@2|Bacteria,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,4HADT@91061|Bacilli,2Y9KI@289201|Pontibacillus 91061|Bacilli KT ATPase AAA bkdR - - - - - - - - - - - DapB_N,HTH_8,PAS,Sigma54_activat k141_17738_2 218284.CCDN010000006_gene3569 1.65e-21 91.7 COG2199@1|root,COG3706@2|Bacteria,1V2QN@1239|Firmicutes,4HFY9@91061|Bacilli,1ZS2E@1386|Bacillus 91061|Bacilli T 5TMR of 5TMR-LYT yhcK1 - 2.7.7.65 ko:K18967 - - - - ko00000,ko01000,ko02000 9.B.34.1.1 - - 5TM-5TMR_LYT,GGDEF k141_30555_2 1244869.H261_21174 7.71e-15 77.4 COG1974@1|root,COG1974@2|Bacteria,1MZFA@1224|Proteobacteria,2UCXW@28211|Alphaproteobacteria,2JUZ3@204441|Rhodospirillales 204441|Rhodospirillales KT COG1974 SOS-response transcriptional repressors (RecA-mediated autopeptidases) - - - ko:K03503 - - - - ko00000,ko01000,ko01002,ko03400 - - - Peptidase_S24 k141_33166_1 218284.CCDN010000006_gene3590 6.61e-63 196.0 COG3278@1|root,COG3278@2|Bacteria,1VAHS@1239|Firmicutes,4HKKG@91061|Bacilli,1ZID0@1386|Bacillus 91061|Bacilli O COG3278 Cbb3-type cytochrome oxidase, subunit 1 - - - - - - - - - - - - COX1 k141_3666_1 1279017.AQYJ01000023_gene3109 6.77e-157 451.0 COG2925@1|root,COG2925@2|Bacteria,1MV0U@1224|Proteobacteria,1RM85@1236|Gammaproteobacteria,464RJ@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG2925 Exonuclease I sbcB GO:0000175,GO:0000287,GO:0000738,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004532,GO:0004536,GO:0004540,GO:0005488,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0008852,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016829,GO:0016835,GO:0016895,GO:0016896,GO:0019439,GO:0034641,GO:0034655,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0046872,GO:0051575,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0140097,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575 3.1.11.1 ko:K01141 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_X-T_C,RNase_T k141_6040_1 218284.CCDN010000008_gene4251 2.12e-89 279.0 COG2199@1|root,COG2203@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,1TQ2X@1239|Firmicutes,4HA6T@91061|Bacilli,1ZCE7@1386|Bacillus 91061|Bacilli T COG2199 FOG GGDEF domain ytrP - - - - - - - - - - - GAF_2,GAF_3,GGDEF k141_21506_1 714961.BFZC1_00105 5.95e-89 271.0 COG0640@1|root,COG0640@2|Bacteria,1TSRQ@1239|Firmicutes,4HBXM@91061|Bacilli 91061|Bacilli K arsR family transcriptional regulator - - - - - - - - - - - - HTH_20,HTH_5 k141_36907_1 1196031.ALEG01000039_gene1286 8.11e-230 639.0 COG1783@1|root,COG1783@2|Bacteria,1TT2C@1239|Firmicutes,4H9S2@91061|Bacilli,1ZCZD@1386|Bacillus 91061|Bacilli S Terminase-like family - - - - - - - - - - - - Terminase_3,Terminase_6,Terminase_6C k141_36907_2 374526.A5GYP7_9CAUD 1.56e-51 168.0 4QAKE@10239|Viruses,4QPCE@28883|Caudovirales 28883|Caudovirales S endonuclease activity - - - - - - - - - - - - - k141_36907_6 743966.MYB_02680 4.42e-58 200.0 COG0270@1|root,COG0863@1|root,COG1092@1|root,COG0270@2|Bacteria,COG0863@2|Bacteria,COG1092@2|Bacteria,3WT0K@544448|Tenericutes 544448|Tenericutes H Methyltransferase - - 2.1.1.37,2.1.1.72 ko:K00558,ko:K00571 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase,N6_N4_Mtase k141_19095_1 1453501.JELR01000002_gene486 5.24e-144 433.0 COG1629@1|root,COG4771@2|Bacteria,1MUWN@1224|Proteobacteria,1S005@1236|Gammaproteobacteria,46A62@72275|Alteromonadaceae 1236|Gammaproteobacteria P Outer membrane protein beta-barrel family - - - - - - - - - - - - Plug,TonB_dep_Rec k141_25023_1 218284.CCDN010000001_gene806 2.56e-87 273.0 COG1368@1|root,COG1368@2|Bacteria,1TRMA@1239|Firmicutes,4H9S0@91061|Bacilli,1ZBBV@1386|Bacillus 91061|Bacilli M Belongs to the LTA synthase family yqgS - 2.7.8.20 ko:K01138,ko:K19005 ko00561,ko01100,map00561,map01100 - R05081,R10849 RC00017 ko00000,ko00001,ko01000 - - - Sulfatase k141_26246_1 1453501.JELR01000002_gene456 9.62e-99 290.0 COG1510@1|root,COG1510@2|Bacteria,1RA49@1224|Proteobacteria,1RRGB@1236|Gammaproteobacteria,466H1@72275|Alteromonadaceae 1236|Gammaproteobacteria K Belongs to the GbsR family - - - - - - - - - - - - HTH_11,HTH_5,MarR,MarR_2 k141_26246_2 1453501.JELR01000002_gene457 9.81e-278 766.0 COG1271@1|root,COG1271@2|Bacteria,1MV60@1224|Proteobacteria,1RN2U@1236|Gammaproteobacteria,4642Q@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1271 Cytochrome bd-type quinol oxidase, subunit 1 cydA - 1.10.3.14 ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - Cyt_bd_oxida_I k141_4849_2 1144342.PMI40_01428 7.21e-62 197.0 COG0625@1|root,COG0625@2|Bacteria,1MXHH@1224|Proteobacteria,2WF67@28216|Betaproteobacteria,478IX@75682|Oxalobacteraceae 28216|Betaproteobacteria O Belongs to the GST superfamily - - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C,GST_N k141_16699_1 1042377.AFPJ01000007_gene1870 5.51e-126 389.0 COG3127@1|root,COG3127@2|Bacteria,1QXGA@1224|Proteobacteria,1T3BG@1236|Gammaproteobacteria,467CX@72275|Alteromonadaceae 1236|Gammaproteobacteria Q COG0577 ABC-type antimicrobial peptide transport system, permease component - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX k141_16699_2 626887.J057_02925 1.01e-61 199.0 COG1136@1|root,COG1136@2|Bacteria,1QU8Q@1224|Proteobacteria,1T3BF@1236|Gammaproteobacteria,46D5G@72275|Alteromonadaceae 1236|Gammaproteobacteria V ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_16699_3 1122179.KB890426_gene3941 4.35e-107 322.0 COG2374@1|root,COG2374@2|Bacteria,4NI8T@976|Bacteroidetes,1ISCV@117747|Sphingobacteriia 976|Bacteroidetes L Endonuclease/Exonuclease/phosphatase family - - - - - - - - - - - - Exo_endo_phos k141_16699_5 1429046.RR21198_1600 6.19e-11 65.1 COG1073@1|root,COG1073@2|Bacteria,2HHN0@201174|Actinobacteria,4FZAE@85025|Nocardiaceae 201174|Actinobacteria S Serine aminopeptidase, S33 - - - - - - - - - - - - Abhydrolase_1,Hydrolase_4 k141_17945_1 218284.CCDN010000001_gene744 6.39e-125 365.0 COG4864@1|root,COG4864@2|Bacteria,1TPTD@1239|Firmicutes,4HAIX@91061|Bacilli,1ZD1V@1386|Bacillus 91061|Bacilli S UPF0365 protein yqfA - - - - - - - - - - - YdfA_immunity k141_17945_2 218284.CCDN010000001_gene743 1.02e-56 189.0 COG1030@1|root,COG1030@2|Bacteria,1TR54@1239|Firmicutes,4H9P9@91061|Bacilli,1ZCTF@1386|Bacillus 91061|Bacilli O COG1030 Membrane-bound serine protease (ClpP class) yqeZ - - ko:K07403 - - - - ko00000 - - - NfeD,SDH_sah k141_21507_1 218284.CCDN010000001_gene661 6.98e-161 471.0 COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,1TQVT@1239|Firmicutes,4HB6K@91061|Bacilli,1ZBS9@1386|Bacillus 91061|Bacilli U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secD GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD_SecF,Sec_GG k141_35746_1 218284.CCDN010000002_gene2827 5.79e-57 181.0 COG1476@1|root,COG1476@2|Bacteria,1V7SJ@1239|Firmicutes 1239|Firmicutes K XRE family transcriptional regulator - - - - - - - - - - - - HTH_3 k141_13185_1 1279017.AQYJ01000027_gene1578 7.39e-160 464.0 COG2206@1|root,COG2206@2|Bacteria,1MW7F@1224|Proteobacteria,1RPEZ@1236|Gammaproteobacteria,465PC@72275|Alteromonadaceae 1236|Gammaproteobacteria T Domain of unknown function (DUF3391) - - - - - - - - - - - - DUF3391,HD_5 k141_13185_2 1453501.JELR01000002_gene938 1.21e-67 219.0 COG0477@1|root,COG2814@2|Bacteria,1QUD1@1224|Proteobacteria,1RQ0V@1236|Gammaproteobacteria,463Z1@72275|Alteromonadaceae 1236|Gammaproteobacteria EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 k141_26247_1 935836.JAEL01000058_gene1165 3.53e-34 122.0 COG1595@1|root,COG1595@2|Bacteria,1UZSS@1239|Firmicutes,4HJ8P@91061|Bacilli,1ZCIU@1386|Bacillus 91061|Bacilli K Sigma-70, region 4 - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_31008_1 223926.28807450 0.0 954.0 COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,1RNBF@1236|Gammaproteobacteria,1XUR3@135623|Vibrionales 135623|Vibrionales J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction pnp GO:0003674,GO:0003824,GO:0004654,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.8 ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 M00394 R00437,R00438,R00439,R00440 RC02795 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 - - - KH_1,PNPase,RNase_PH,RNase_PH_C,S1 k141_7200_1 218284.CCDN010000001_gene1750 2.25e-119 358.0 COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,1TPYV@1239|Firmicutes,4HAB5@91061|Bacilli,1ZBGC@1386|Bacillus 91061|Bacilli E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine yitJ - 1.5.1.20,2.1.1.10 ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 M00377 R00650,R01224,R07168 RC00003,RC00035,RC00081 ko00000,ko00001,ko00002,ko01000 - - - MTHFR,S-methyl_trans k141_27397_1 243277.VC_1359 9.11e-62 195.0 COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,1RMX1@1236|Gammaproteobacteria,1XTEU@135623|Vibrionales 135623|Vibrionales E COG1126 ABC-type polar amino acid transport system, ATPase component aapP - 3.6.3.21 ko:K02028,ko:K09972 ko02010,map02010 M00232,M00236 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3,3.A.1.3.17,3.A.1.3.18,3.A.1.3.7,3.A.1.3.8 - - ABC_tran k141_27397_2 1280001.BAOA01000077_gene3078 2.64e-138 393.0 COG0670@1|root,COG0670@2|Bacteria,1MU69@1224|Proteobacteria,1RRVZ@1236|Gammaproteobacteria,1XTWT@135623|Vibrionales 135623|Vibrionales S Belongs to the BI1 family yccA - - ko:K19416 - M00742 - - ko00000,ko00002,ko02000 1.A.14.2.1 - - Bax1-I k141_27397_3 1116375.VEJY3_07715 3.32e-76 228.0 2CZQD@1|root,32T6U@2|Bacteria,1N0VG@1224|Proteobacteria,1SB5H@1236|Gammaproteobacteria,1XXIF@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_6044_1 555079.Toce_2266 5.72e-22 95.1 COG1597@1|root,COG1597@2|Bacteria,1TQJH@1239|Firmicutes,24BHT@186801|Clostridia 186801|Clostridia I lipid kinase, YegS Rv2252 BmrU family ytlR - - - - - - - - - - - DAGK_cat k141_6044_2 7217.FBpp0120820 3.61e-10 61.2 COG3320@1|root,KOG1221@2759|Eukaryota,39YXW@33154|Opisthokonta,3BJZH@33208|Metazoa,3D12E@33213|Bilateria,41WRF@6656|Arthropoda,3SH6S@50557|Insecta,450K4@7147|Diptera,45S4C@7214|Drosophilidae 33208|Metazoa I Catalyzes the reduction of fatty acyl-CoA to fatty alcohols - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0010025,GO:0010166,GO:0016491,GO:0016620,GO:0016903,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035336,GO:0035337,GO:0035383,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0080019,GO:1901135,GO:1901360,GO:1901564,GO:1901568,GO:1901570,GO:1901576 1.2.1.84 ko:K13356 ko00073,ko04146,ko04212,map00073,map04146,map04212 - R09470 RC00004 ko00000,ko00001,ko01000 - - - NAD_binding_4,Sterile k141_29790_3 675814.VIC_002629 7.25e-08 53.1 COG0362@1|root,COG0362@2|Bacteria,1MVV8@1224|Proteobacteria,1RM7P@1236|Gammaproteobacteria,1XVCB@135623|Vibrionales 135623|Vibrionales H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH - - 1.1.1.343,1.1.1.44 ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 M00004,M00006 R01528,R10221 RC00001,RC00539 ko00000,ko00001,ko00002,ko01000 - - - 6PGD,NAD_binding_2 k141_28632_1 218284.CCDN010000002_gene2126 1.03e-197 555.0 COG0460@1|root,COG0460@2|Bacteria,1TQ2H@1239|Firmicutes,4HBAP@91061|Bacilli,1ZAVJ@1386|Bacillus 91061|Bacilli E homoserine dehydrogenase hom - 1.1.1.3 ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00017,M00018 R01773,R01775 RC00087 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS06610 ACT,Homoserine_dh,NAD_binding_3 k141_2488_1 1279017.AQYJ01000025_gene732 0.0 884.0 COG0057@1|root,COG0057@2|Bacteria,1MZE4@1224|Proteobacteria,1RMSI@1236|Gammaproteobacteria,465BD@72275|Alteromonadaceae 1236|Gammaproteobacteria G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family gap - 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N k141_2488_2 1279017.AQYJ01000025_gene733 4.64e-243 704.0 COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,1RNCU@1236|Gammaproteobacteria,464IX@72275|Alteromonadaceae 1236|Gammaproteobacteria L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd GO:0000715,GO:0000716,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006283,GO:0006289,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008094,GO:0008150,GO:0008152,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0015616,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031326,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0043175,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051276,GO:0051716,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF k141_8439_1 1499967.BAYZ01000154_gene1496 1.08e-59 207.0 COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,2NP1D@2323|unclassified Bacteria 2|Bacteria M Transglycosylase SLT domain mltD - - ko:K08307,ko:K12204,ko:K16291 - - - - ko00000,ko01000,ko01002,ko01011,ko02044 3.A.7.10.1,3.A.7.9.1 - - LysM,SLT,T4SS_TraI k141_1234_1 1279017.AQYJ01000026_gene171 2.62e-227 707.0 COG3209@1|root,COG4733@1|root,COG3209@2|Bacteria,COG4733@2|Bacteria,1MVV1@1224|Proteobacteria,1RMPT@1236|Gammaproteobacteria,464DD@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG3209 Rhs family protein - - - - - - - - - - - - RHS_repeat,SpvB,TcdB_toxin_midN,VCBS k141_33366_1 290398.Csal_0719 6.39e-242 670.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,1RNAM@1236|Gammaproteobacteria 1236|Gammaproteobacteria G TRAP-type C4-dicarboxylate transport system, large permease component - - - - - - - - - - - - DctM k141_15553_1 1279017.AQYJ01000027_gene1808 0.0 1102.0 COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,1RMM1@1236|Gammaproteobacteria,465DI@72275|Alteromonadaceae 1236|Gammaproteobacteria D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 gidA GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - ko:K03495 - - R08701 RC00053,RC00209,RC00870 ko00000,ko03016,ko03036 - - - GIDA,GIDA_assoc k141_14362_1 1026882.MAMP_02136 1.23e-30 121.0 COG0642@1|root,COG2205@2|Bacteria,1N1Z2@1224|Proteobacteria,1RPG9@1236|Gammaproteobacteria,460R7@72273|Thiotrichales 72273|Thiotrichales T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - 2.7.13.3 ko:K07645 ko02020,ko02024,map02020,map02024 M00453 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - 2CSK_N,HATPase_c,HisKA k141_14362_2 527002.yaldo0001_30590 1.64e-66 211.0 COG0745@1|root,COG0745@2|Bacteria,1N0YI@1224|Proteobacteria,1RPNH@1236|Gammaproteobacteria,41D55@629|Yersinia 1236|Gammaproteobacteria K Transcriptional regulatory protein basR basR GO:0000156,GO:0000160,GO:0003674,GO:0006355,GO:0007154,GO:0007165,GO:0008150,GO:0009889,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0010041,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0023052,GO:0031323,GO:0031326,GO:0035556,GO:0042221,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051716,GO:0060089,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K07771 ko01503,ko02020,map01503,map02020 M00451,M00721,M00722 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C k141_17946_1 218284.CCDN010000010_gene4334 7.92e-51 167.0 COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,4HCFI@91061|Bacilli,1ZCC7@1386|Bacillus 91061|Bacilli J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs truA GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 ko:K06173 - - - - ko00000,ko01000,ko03016 - - - PseudoU_synth_1 k141_22687_1 1517681.HW45_21180 2.89e-114 327.0 COG0346@1|root,COG0346@2|Bacteria,1QEI0@1224|Proteobacteria,1RRJ9@1236|Gammaproteobacteria,1XUJU@135623|Vibrionales 135623|Vibrionales E COG0346 Lactoylglutathione lyase and related lyases - - - - - - - - - - - - Glyoxalase k141_29791_1 1453501.JELR01000002_gene575 3.6e-98 295.0 COG4177@1|root,COG4177@2|Bacteria,1MUPI@1224|Proteobacteria,1RMAZ@1236|Gammaproteobacteria,464E0@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the binding-protein-dependent transport system permease family urtC - - ko:K01998,ko:K11961 ko02010,ko02024,map02010,map02024 M00237,M00323 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4,3.A.1.4.4,3.A.1.4.5 - - BPD_transp_2 k141_29791_2 1453501.JELR01000002_gene576 3.13e-21 91.7 COG0559@1|root,COG0559@2|Bacteria,1MVND@1224|Proteobacteria,1RQXD@1236|Gammaproteobacteria,46515@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the binding-protein-dependent transport system permease family urtB - - ko:K11960 ko02010,map02010 M00323 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4.4,3.A.1.4.5 - - BPD_transp_2,HEAT_2 k141_4850_1 218284.CCDN010000002_gene2169 9.54e-50 160.0 2B02J@1|root,31SCS@2|Bacteria,1V9YF@1239|Firmicutes,4HKUD@91061|Bacilli,1ZHUD@1386|Bacillus 91061|Bacilli - - liaI - - ko:K11619 ko02020,map02020 M00754 - - ko00000,ko00001,ko00002 - - - - k141_8440_1 1340434.AXVA01000010_gene5313 2.86e-113 332.0 COG1494@1|root,COG1494@2|Bacteria,1TP0D@1239|Firmicutes,4H9MV@91061|Bacilli,1ZC28@1386|Bacillus 91061|Bacilli G fructose-1,6-bisphosphatase glpX GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030388,GO:0042132,GO:0042578,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0050308,GO:0071704,GO:1901135,GO:1901576 3.1.3.11 ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 M00003,M00165,M00167 R00762,R04780 RC00017 ko00000,ko00001,ko00002,ko01000 - - - FBPase_glpX k141_21509_1 1461580.CCAS010000001_gene82 1.26e-06 52.0 COG0665@1|root,COG0665@2|Bacteria,1VTRW@1239|Firmicutes,4HN9Q@91061|Bacilli,1ZQFA@1386|Bacillus 91061|Bacilli E FAD dependent oxidoreductase - - - - - - - - - - - - DAO k141_21509_2 218284.CCDN010000001_gene1449 3.07e-61 197.0 COG0352@1|root,COG0352@2|Bacteria,1V6KJ@1239|Firmicutes,4HIM9@91061|Bacilli,1ZH29@1386|Bacillus 91061|Bacilli H Transcriptional regulator TenI tenI GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3,5.3.99.10 ko:K00788,ko:K10810 ko00730,ko01100,map00730,map01100 M00127 R03223,R09977,R10712 RC00224,RC02766,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000,ko03000 - - - TMP-TENI k141_1241_6 1116375.VEJY3_02790 1.74e-126 362.0 COG2976@1|root,COG2976@2|Bacteria,1N117@1224|Proteobacteria,1SASA@1236|Gammaproteobacteria,1XTXY@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria - - - - - - - - - - - - TPR_21 k141_1241_7 1116375.VEJY3_02785 2.35e-304 830.0 COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,1RPHI@1236|Gammaproteobacteria,1XTDT@135623|Vibrionales 135623|Vibrionales J Histidyl-tRNA synthetase hisS GO:0003674,GO:0003824,GO:0004812,GO:0004821,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006427,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_His k141_1241_8 223926.28805594 3.82e-255 701.0 COG0821@1|root,COG0821@2|Bacteria,1MUAX@1224|Proteobacteria,1RMXZ@1236|Gammaproteobacteria,1XSUH@135623|Vibrionales 135623|Vibrionales I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate ispG GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R08689,R10859 RC01486 ko00000,ko00001,ko00002,ko01000 - - - GcpE k141_1241_9 1116375.VEJY3_02775 7.25e-143 412.0 COG1426@1|root,COG1426@2|Bacteria,1N240@1224|Proteobacteria,1RQMV@1236|Gammaproteobacteria,1XSGH@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria rodZ - - ko:K15539 - - - - ko00000 - - - DUF4115,HTH_25 k141_1241_10 223926.28805591 5.83e-272 744.0 COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,1RMUI@1236|Gammaproteobacteria,1XSQG@135623|Vibrionales 135623|Vibrionales J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs rlmN GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 ko:K06941 - - - - ko00000,ko01000,ko03009 - - - Radical_SAM k141_1241_11 1116375.VEJY3_02765 6.12e-94 274.0 COG0105@1|root,COG0105@2|Bacteria,1R9ZA@1224|Proteobacteria,1S1Z3@1236|Gammaproteobacteria,1XX25@135623|Vibrionales 135623|Vibrionales F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate ndk GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 M00049,M00050,M00052,M00053 R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895 RC00002 ko00000,ko00001,ko00002,ko01000,ko04131 - - - NDK k141_1241_12 1116375.VEJY3_02760 3.1e-305 833.0 COG0260@1|root,COG0260@2|Bacteria,1MUIN@1224|Proteobacteria,1RNFI@1236|Gammaproteobacteria,1XUTG@135623|Vibrionales 135623|Vibrionales E Probably plays an important role in intracellular peptide degradation pepB GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564 3.4.11.23 ko:K07751 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - DUF3663,Peptidase_M17 k141_1241_13 223926.28805588 2.38e-44 143.0 COG2975@1|root,COG2975@2|Bacteria,1N7C1@1224|Proteobacteria,1SC9F@1236|Gammaproteobacteria,1XYVQ@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria iscX - - - - - - - - - - - Fe-S_assembly k141_1241_14 1280001.BAOA01000163_gene2077 2.88e-76 227.0 COG0633@1|root,COG0633@2|Bacteria,1RHDC@1224|Proteobacteria,1S5XW@1236|Gammaproteobacteria,1XXAG@135623|Vibrionales 135623|Vibrionales C Ferredoxin fdx - - ko:K04755 - - - - ko00000 - - - Fer2 k141_1241_15 1219076.N646_2758 1.43e-64 213.0 COG0443@1|root,COG0443@2|Bacteria,1MVQI@1224|Proteobacteria,1RN74@1236|Gammaproteobacteria,1XT9W@135623|Vibrionales 135623|Vibrionales O Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB hscA GO:0006457,GO:0008150,GO:0009987 - ko:K04044 - - - - ko00000,ko03110 1.A.33 - - HSP70 k141_28668_1 1479237.JMLY01000001_gene3330 1.14e-58 185.0 2C3KM@1|root,32UH0@2|Bacteria,1N3F2@1224|Proteobacteria,1S9U2@1236|Gammaproteobacteria,46B2R@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_28668_2 637390.AFOH01000149_gene217 9.92e-130 371.0 COG0450@1|root,COG0450@2|Bacteria,1MX2B@1224|Proteobacteria,1RPQV@1236|Gammaproteobacteria,2NDXF@225057|Acidithiobacillales 225057|Acidithiobacillales O C-terminal domain of 1-Cys peroxiredoxin - - 1.11.1.15 ko:K03386 ko04214,map04214 - - - ko00000,ko00001,ko01000,ko04147 - - - 1-cysPrx_C,AhpC-TSA k141_28668_3 1453501.JELR01000002_gene1013 1.93e-257 723.0 COG2176@1|root,COG2176@2|Bacteria,1MUZD@1224|Proteobacteria,1RPGP@1236|Gammaproteobacteria,4645Z@72275|Alteromonadaceae 1236|Gammaproteobacteria L VRR_NUC - - - - - - - - - - - - VRR_NUC k141_28668_4 1279017.AQYJ01000025_gene483 4.48e-286 808.0 COG1199@1|root,COG1199@2|Bacteria,1MVRJ@1224|Proteobacteria,1RQ7B@1236|Gammaproteobacteria,464G6@72275|Alteromonadaceae 1236|Gammaproteobacteria KL COG1199 Rad3-related DNA helicases - - 3.6.4.12 ko:K10844 ko03022,ko03420,map03022,map03420 M00290 - - ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - DEAD_2,Helicase_C_2 k141_31031_1 118168.MC7420_3458 1.57e-93 275.0 COG3464@1|root,COG3464@2|Bacteria,1G377@1117|Cyanobacteria,1HDCU@1150|Oscillatoriales 1117|Cyanobacteria L PFAM transposase IS66 - - - ko:K07484 - - - - ko00000 - - - DDE_Tnp_IS66 k141_27414_1 1200792.AKYF01000019_gene4610 1.76e-39 143.0 COG3173@1|root,COG3173@2|Bacteria,1V3EC@1239|Firmicutes,4HGMP@91061|Bacilli,274RI@186822|Paenibacillaceae 91061|Bacilli S Phosphotransferase enzyme family - - 2.7.1.190 ko:K17910 - - R11229 RC00002,RC00078 ko00000,ko01000,ko01504 - - - APH k141_23855_1 1294265.JCM21738_2910 6.41e-32 111.0 2EIIR@1|root,33CA1@2|Bacteria,1VMUM@1239|Firmicutes,4HSC6@91061|Bacilli,1ZJ19@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_23855_2 1294265.JCM21738_2911 2.24e-45 146.0 2E3WD@1|root,32YTI@2|Bacteria,1VGKG@1239|Firmicutes,4HSKD@91061|Bacilli,1ZIY3@1386|Bacillus 91061|Bacilli S Family of unknown function (DUF5342) yheE - - - - - - - - - - - DUF5342 k141_26296_1 1502851.FG93_06077 4.87e-53 182.0 COG0760@1|root,COG0760@2|Bacteria,1R4ZR@1224|Proteobacteria,2U874@28211|Alphaproteobacteria,3JRK1@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O PPIC-type PPIASE domain - - 5.2.1.8 ko:K03769 - - - - ko00000,ko01000,ko03110 - - - Rotamase_2 k141_26296_2 1042377.AFPJ01000011_gene427 1.15e-51 176.0 COG2370@1|root,COG2370@2|Bacteria,1MV6Z@1224|Proteobacteria,1RRHA@1236|Gammaproteobacteria,468HI@72275|Alteromonadaceae 1236|Gammaproteobacteria O HupE / UreJ protein - - - - - - - - - - - - HupE_UreJ_2 k141_15595_1 314287.GB2207_11278 8.28e-135 400.0 COG0015@1|root,COG0015@2|Bacteria,1MXNN@1224|Proteobacteria,1RS00@1236|Gammaproteobacteria,1J9YW@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria F Adenylosuccinate lyase C-terminus - - 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 - - - ADSL_C,Lyase_1 k141_14397_1 1280944.HY17_06015 1.43e-44 152.0 COG1309@1|root,COG1309@2|Bacteria,1R7F8@1224|Proteobacteria,2U0DG@28211|Alphaproteobacteria,43YV2@69657|Hyphomonadaceae 28211|Alphaproteobacteria K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N k141_144_1 1121346.KB899846_gene34 5.84e-54 188.0 COG1154@1|root,COG1154@2|Bacteria,1TP37@1239|Firmicutes,4H9QW@91061|Bacilli,26QZ7@186822|Paenibacillaceae 91061|Bacilli H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) dxs - 2.2.1.7 ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 M00096 R05636 RC00032 ko00000,ko00001,ko00002,ko01000 - - - DXP_synthase_N,Transket_pyr,Transketolase_C k141_3692_1 218284.CCDN010000005_gene3214 5.18e-201 564.0 COG0501@1|root,COG0501@2|Bacteria,1TRQE@1239|Firmicutes,4HD5G@91061|Bacilli,1ZC4F@1386|Bacillus 91061|Bacilli O Peptidase M48 yhfN GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0070011,GO:0071586,GO:0071704,GO:0080120,GO:0140096,GO:1901564 - - - - - - - - - - Peptidase_M48,Peptidase_M48_N k141_28669_1 1294265.JCM21738_1985 2.26e-87 258.0 COG0526@1|root,COG0526@2|Bacteria,1V3YC@1239|Firmicutes,4HJ8N@91061|Bacilli,1ZH2W@1386|Bacillus 91061|Bacilli CO Thioredoxin bdbA - - - - - - - - - - - Thioredoxin k141_13220_1 218284.CCDN010000001_gene1935 1.62e-37 128.0 COG1815@1|root,COG1815@2|Bacteria,1VEUZ@1239|Firmicutes,4HIKW@91061|Bacilli,1ZHSN@1386|Bacillus 91061|Bacilli N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body flgB - - ko:K02387 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod k141_6072_2 985255.APHJ01000021_gene1816 3.47e-21 97.4 COG0791@1|root,COG0791@2|Bacteria,4NE2T@976|Bacteroidetes,1HXZ5@117743|Flavobacteriia,2P5QM@244698|Gillisia 976|Bacteroidetes M Bacterial SH3 domain ykfC - - - - - - - - - - - NLPC_P60,SH3_3 k141_7224_1 218284.CCDN010000008_gene4174 5.54e-87 279.0 COG4412@1|root,COG4412@2|Bacteria,1TQYP@1239|Firmicutes,4HD82@91061|Bacilli,1ZPVI@1386|Bacillus 91061|Bacilli S Immune inhibitor A peptidase M6 - - - ko:K09607 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M6 k141_36926_2 1280698.AUJS01000042_gene3279 3.9e-26 106.0 COG2265@1|root,COG2265@2|Bacteria,1UK4G@1239|Firmicutes,24H6A@186801|Clostridia,27W5R@189330|Dorea 186801|Clostridia J Tellurite resistance protein TehB - - - - - - - - - - - - Methyltransf_25 k141_145_1 1294265.JCM21738_4267 5.79e-96 284.0 COG1073@1|root,COG1073@2|Bacteria,1TQYU@1239|Firmicutes,4HC4H@91061|Bacilli,1ZBDV@1386|Bacillus 91061|Bacilli S COG1073 Hydrolases of the alpha beta superfamily - - - ko:K06889 - - - - ko00000 - - - Hydrolase_4 k141_11976_1 218284.CCDN010000001_gene1521 2.14e-68 214.0 COG1346@1|root,COG1346@2|Bacteria,1TRGN@1239|Firmicutes,4HF0M@91061|Bacilli,1ZFQ6@1386|Bacillus 91061|Bacilli M effector of murein hydrolase - - - - - - - - - - - - LrgB k141_14398_1 218284.CCDN010000007_gene3906 1.13e-134 387.0 COG0451@1|root,COG0451@2|Bacteria,1TSUN@1239|Firmicutes,4HA3D@91061|Bacilli,1ZAUE@1386|Bacillus 91061|Bacilli GM GDP-mannose 4,6 dehydratase - - - - - - - - - - - - Epimerase k141_31033_1 218284.CCDN010000001_gene36 1.05e-35 121.0 COG0227@1|root,COG0227@2|Bacteria,1VEI2@1239|Firmicutes,4HNIK@91061|Bacilli,1ZIVY@1386|Bacillus 91061|Bacilli J Belongs to the bacterial ribosomal protein bL28 family rpmB - - ko:K02902 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L28 k141_13221_1 1042377.AFPJ01000036_gene1142 1.06e-112 339.0 COG1680@1|root,COG1680@2|Bacteria,1MVZN@1224|Proteobacteria,1RP0R@1236|Gammaproteobacteria,468BI@72275|Alteromonadaceae 1236|Gammaproteobacteria V Beta-lactamase - - - - - - - - - - - - Beta-lactamase,DUF3471 k141_3693_1 861299.J421_1393 2.02e-35 139.0 COG0308@1|root,COG0308@2|Bacteria,1ZUT0@142182|Gemmatimonadetes 142182|Gemmatimonadetes E Peptidase family M1 domain - - - - - - - - - - - - Peptidase_M1 k141_15597_1 891974.E05_44970 1.07e-23 99.4 COG3547@1|root,COG3547@2|Bacteria,1MXKJ@1224|Proteobacteria,1RSCP@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Transposase - - - - - - - - - - - - DEDD_Tnp_IS110,Transposase_20 k141_26297_1 218284.CCDN010000001_gene1689 8.11e-82 250.0 COG1277@1|root,COG1277@2|Bacteria,1TRD6@1239|Firmicutes,4HGGV@91061|Bacilli,1ZC8J@1386|Bacillus 91061|Bacilli S ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_2 k141_26297_2 796606.BMMGA3_16495 8.22e-09 55.8 COG1277@1|root,COG1277@2|Bacteria,1V6DZ@1239|Firmicutes,4HFY3@91061|Bacilli,1ZCE6@1386|Bacillus 91061|Bacilli S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_2 k141_27416_1 1121935.AQXX01000116_gene5197 2.11e-115 340.0 COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,1RN0B@1236|Gammaproteobacteria,1XJ42@135619|Oceanospirillales 135619|Oceanospirillales NU Type II/IV secretion system protein - - - ko:K02670 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE k141_36927_1 218284.CCDN010000001_gene639 9.47e-123 355.0 COG0077@1|root,COG0077@2|Bacteria,1TPDN@1239|Firmicutes,4HA96@91061|Bacilli,1ZAVW@1386|Bacillus 91061|Bacilli E Prephenate dehydratase pheA GO:0003674,GO:0003824,GO:0004664,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0019438,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 4.2.1.51 ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024 R00691,R01373 RC00360 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU27900 ACT,PDT k141_2500_1 218284.CCDN010000007_gene4000 5.28e-69 215.0 COG0224@1|root,COG0224@2|Bacteria,1TPBX@1239|Firmicutes,4HB0E@91061|Bacilli,1ZCKT@1386|Bacillus 91061|Bacilli C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex atpG - - ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - iSB619.SA_RS10970,iYO844.BSU36820 ATP-synt k141_7364_5 1116375.VEJY3_17341 5.04e-80 245.0 COG1816@1|root,COG1816@2|Bacteria,1MWBV@1224|Proteobacteria,1RNVI@1236|Gammaproteobacteria,1XU77@135623|Vibrionales 135623|Vibrionales F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism - - 3.5.4.2 ko:K21053 ko00230,ko01100,map00230,map01100 - R01244 RC00477 ko00000,ko00001,ko01000 - - - A_deaminase k141_35838_2 1321784.HMPREF1987_02151 1.85e-12 71.6 COG0543@1|root,COG0543@2|Bacteria,1TQ5D@1239|Firmicutes,24AY2@186801|Clostridia,25QJ7@186804|Peptostreptococcaceae 186801|Clostridia C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( pyrK - - ko:K02823 ko00240,ko01100,map00240,map01100 - - - ko00000,ko00001 - - iHN637.CLJU_RS17580 DHODB_Fe-S_bind,NAD_binding_1 k141_21659_1 218284.CCDN010000007_gene3810 3.59e-163 479.0 COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,4H9RZ@91061|Bacilli,1ZBEA@1386|Bacillus 91061|Bacilli NT chemotaxis protein mcpC GO:0005575,GO:0005623,GO:0005886,GO:0006935,GO:0008150,GO:0009605,GO:0016020,GO:0040011,GO:0042221,GO:0042330,GO:0044464,GO:0050896,GO:0050918,GO:0071944 - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal,dCache_1 k141_34668_1 498211.CJA_0484 5.39e-105 309.0 COG0625@1|root,COG0625@2|Bacteria,1PHM1@1224|Proteobacteria,1RMVC@1236|Gammaproteobacteria,1FI43@10|Cellvibrio 1236|Gammaproteobacteria O Glutathione S-transferase, N-terminal domain - - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C_2,GST_N,GST_N_3 k141_34668_2 1279017.AQYJ01000029_gene3516 1.17e-295 811.0 COG3200@1|root,COG3200@2|Bacteria,1MUWF@1224|Proteobacteria,1RRMM@1236|Gammaproteobacteria,46548@72275|Alteromonadaceae 1236|Gammaproteobacteria E phospho-2-dehydro-3-deoxyheptonate aldolase aroH - 2.5.1.54 ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 - - - DAHP_synth_2 k141_34668_3 1279017.AQYJ01000029_gene3515 1.02e-246 682.0 COG1448@1|root,COG1448@2|Bacteria,1MUT0@1224|Proteobacteria,1RN02@1236|Gammaproteobacteria,4647G@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG1448 Aspartate tyrosine aromatic aminotransferase aspC - 2.6.1.1,2.6.1.57 ko:K00813,ko:K00832 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 M00024,M00025,M00034,M00040 R00355,R00694,R00734,R00896,R01731,R02433,R02619,R05052,R07396,R10845 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k141_34668_4 1042377.AFPJ01000009_gene293 6.28e-89 264.0 COG1846@1|root,COG1846@2|Bacteria,1N1CJ@1224|Proteobacteria,1SCUJ@1236|Gammaproteobacteria,467UJ@72275|Alteromonadaceae 1236|Gammaproteobacteria K helix_turn_helix multiple antibiotic resistance protein - - - - - - - - - - - - MarR,MarR_2 k141_37048_1 218284.CCDN010000001_gene1531 6.71e-90 278.0 COG0578@1|root,COG0578@2|Bacteria,1TQJN@1239|Firmicutes,4HAG8@91061|Bacilli,1ZCGN@1386|Bacillus 91061|Bacilli C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family glpD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.1.3.21,1.1.5.3 ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 - R00846,R00848 RC00029 ko00000,ko00001,ko01000 - - - DAO,DAO_C k141_12182_1 218284.CCDN010000005_gene3330 1.78e-32 119.0 COG1737@1|root,COG1737@2|Bacteria,1TR0N@1239|Firmicutes,4HB9E@91061|Bacilli,1ZCCD@1386|Bacillus 91061|Bacilli K RpiR family transcriptional regulator gntR - - - - - - - - - - - HTH_6,SIS k141_10913_1 1280949.HAD_03570 7.75e-05 44.3 COG0778@1|root,COG0778@2|Bacteria,1MY39@1224|Proteobacteria,2TTZC@28211|Alphaproteobacteria,43X6X@69657|Hyphomonadaceae 28211|Alphaproteobacteria C Nitroreductase family - - - - - - - - - - - - Nitroreductase k141_10913_2 926550.CLDAP_30830 4.21e-63 200.0 COG0479@1|root,COG0479@2|Bacteria,2G659@200795|Chloroflexi 200795|Chloroflexi C TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein - - 1.3.5.1,1.3.5.4 ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - Fer2_3,Fer4_8 k141_21678_1 1294265.JCM21738_533 2.11e-61 191.0 COG1187@1|root,COG1187@2|Bacteria,1TP68@1239|Firmicutes,4HAVS@91061|Bacilli,1ZC7N@1386|Bacillus 91061|Bacilli J Belongs to the pseudouridine synthase RsuA family rluF - 5.4.99.21 ko:K06182 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 k141_21678_2 935836.JAEL01000107_gene2270 1.47e-35 134.0 COG0477@1|root,COG2814@2|Bacteria,1TRZB@1239|Firmicutes,4HC28@91061|Bacilli,1ZD6T@1386|Bacillus 91061|Bacilli EGP Transmembrane secretion effector - - - - - - - - - - - - MFS_1,MFS_3 k141_25214_1 218284.CCDN010000002_gene2009 3.37e-105 331.0 COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,4HABE@91061|Bacilli,1ZPZA@1386|Bacillus 91061|Bacilli EF Carbamoyl-phosphate synthetase ammonia chain carB GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS k141_28829_1 1042377.AFPJ01000034_gene2400 1.64e-175 498.0 COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,1RPHI@1236|Gammaproteobacteria,464GH@72275|Alteromonadaceae 1236|Gammaproteobacteria J histidyl-tRNA synthetase hisS GO:0003674,GO:0003824,GO:0004812,GO:0004821,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006427,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iE2348C_1286.E2348C_2797,iECNA114_1301.ECNA114_2592,iECSF_1327.ECSF_2358 HGTP_anticodon,tRNA-synt_His k141_32251_2 1273538.G159_09225 1.65e-14 68.6 2DSAK@1|root,33F8X@2|Bacteria,1VQJW@1239|Firmicutes,4HSP5@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - k141_13352_1 1380391.JIAS01000011_gene4883 9.92e-47 172.0 COG1201@1|root,COG1201@2|Bacteria,1MUSW@1224|Proteobacteria,2TR7V@28211|Alphaproteobacteria,2JPDT@204441|Rhodospirillales 204441|Rhodospirillales L DEAD/H associated - - - ko:K03724 - - - - ko00000,ko01000,ko03400 - - - DEAD,DEAD_assoc,Helicase_C k141_37049_1 198094.BA_0338 1.26e-56 183.0 COG1670@1|root,COG1670@2|Bacteria,1V3EY@1239|Firmicutes,4HGKG@91061|Bacilli,1ZG8B@1386|Bacillus 91061|Bacilli J Benzoate transporter - - - - - - - - - - - - Acetyltransf_1 k141_20376_1 218284.CCDN010000005_gene3361 2.71e-119 353.0 COG0168@1|root,COG0168@2|Bacteria,1TQ4S@1239|Firmicutes,4H9ME@91061|Bacilli,1ZD2H@1386|Bacillus 91061|Bacilli P COG0168 Trk-type K transport systems, membrane components ktrD - - - - - - - - - - - TrkH k141_3863_1 218284.CCDN010000008_gene4138 3.49e-162 456.0 COG1734@1|root,COG1734@2|Bacteria,1V4KF@1239|Firmicutes,4HHBC@91061|Bacilli,1ZQQT@1386|Bacillus 91061|Bacilli T Prokaryotic dksA/traR C4-type zinc finger - - - - - - - - - - - - zf-dskA_traR k141_7387_1 218284.CCDN010000001_gene1084 5.55e-149 425.0 COG0492@1|root,COG0492@2|Bacteria,1TQGS@1239|Firmicutes,4HBIS@91061|Bacilli,1ZCBR@1386|Bacillus 91061|Bacilli O COG0492 Thioredoxin reductase ypdA - 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Pyr_redox_3 k141_8561_2 1294265.JCM21738_3129 2.78e-11 60.8 COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,4HA6M@91061|Bacilli,1ZB9G@1386|Bacillus 91061|Bacilli J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family rlmCD GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070041,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.190 ko:K03215 - - - - ko00000,ko01000,ko03009 - - - TRAM,tRNA_U5-meth_tr k141_6309_3 935836.JAEL01000005_gene2677 1.62e-18 83.6 2BZV8@1|root,30HHG@2|Bacteria,1V68P@1239|Firmicutes,4HHRU@91061|Bacilli,1ZF2B@1386|Bacillus 91061|Bacilli S Replication-relaxation - - - - - - - - - - - - Replic_Relax k141_10915_1 1163671.JAGI01000002_gene1005 9.66e-33 130.0 COG0493@1|root,COG1145@1|root,COG0493@2|Bacteria,COG1145@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,36FQY@31979|Clostridiaceae 186801|Clostridia C Oxidoreductase - - - - - - - - - - - - Fer4,Fer4_20,Pyr_redox_2 k141_28830_1 420246.GTNG_0870 3.86e-16 72.4 2EI19@1|root,33BSS@2|Bacteria,1VKXC@1239|Firmicutes,4HR2E@91061|Bacilli,1WH09@129337|Geobacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_18144_1 1453501.JELR01000001_gene3236 1.47e-49 171.0 2C612@1|root,32RGH@2|Bacteria,1RGYZ@1224|Proteobacteria,1S8MM@1236|Gammaproteobacteria,46BBZ@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_7389_1 1131730.BAVI_25579 1.24e-100 296.0 COG2801@1|root,COG2801@2|Bacteria,1TQQY@1239|Firmicutes,4HC8M@91061|Bacilli,1ZBTR@1386|Bacillus 91061|Bacilli L PFAM Integrase catalytic region - - - - - - - - - - - - HTH_21,rve,rve_2 k141_25216_1 1453501.JELR01000002_gene486 2.19e-110 341.0 COG1629@1|root,COG4771@2|Bacteria,1MUWN@1224|Proteobacteria,1S005@1236|Gammaproteobacteria,46A62@72275|Alteromonadaceae 1236|Gammaproteobacteria P Outer membrane protein beta-barrel family - - - - - - - - - - - - Plug,TonB_dep_Rec k141_343_1 1034347.CAHJ01000017_gene3437 4.55e-49 171.0 COG0477@1|root,COG2814@2|Bacteria,1UXYG@1239|Firmicutes,4HBZB@91061|Bacilli,1ZQ79@1386|Bacillus 91061|Bacilli EGP COG0477 Permeases of the major facilitator superfamily ynfM3 - - - - - - - - - - - MFS_1,Sugar_tr k141_28831_1 1227360.C176_18497 2.87e-18 79.3 COG0537@1|root,COG0537@2|Bacteria,1V2XA@1239|Firmicutes,4HGAH@91061|Bacilli,26HB4@186818|Planococcaceae 91061|Bacilli FG adenosine 5'-monophosphoramidase activity - - - - - - - - - - - - - k141_28831_2 1071073.KI530537_gene2486 2.23e-08 55.8 COG1670@1|root,COG1670@2|Bacteria,1V7SS@1239|Firmicutes,4HJGC@91061|Bacilli,1ZIE7@1386|Bacillus 91061|Bacilli J Acetyltransferase (GNAT) family - - 2.3.1.128 ko:K03789 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_1,Acetyltransf_10,Acetyltransf_3 k141_26490_1 395965.Msil_1046 4.77e-56 191.0 2BY5R@1|root,324P3@2|Bacteria,1MYDD@1224|Proteobacteria,2UB2G@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_8562_2 84531.JMTZ01000069_gene1788 3.45e-24 104.0 COG2925@1|root,COG2925@2|Bacteria,1MV0U@1224|Proteobacteria,1RM85@1236|Gammaproteobacteria,1X41G@135614|Xanthomonadales 135614|Xanthomonadales L Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates sbcB - 3.1.11.1 ko:K01141 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_X-T_C,RNase_T k141_14510_1 1219076.N646_4503 5.12e-246 689.0 COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,1RPC3@1236|Gammaproteobacteria,1XU9F@135623|Vibrionales 135623|Vibrionales C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B cyoB - 1.10.3.10 ko:K02298 ko00190,ko01100,map00190,map01100 M00417 R11335 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.5 - - COX1 k141_14510_2 674977.VMC_35650 1.09e-196 546.0 COG1622@1|root,COG1622@2|Bacteria,1MWHZ@1224|Proteobacteria,1RP4H@1236|Gammaproteobacteria,1XUJG@135623|Vibrionales 135623|Vibrionales C subunit 2 cyoA - 1.10.3.10 ko:K02297 ko00190,ko01100,map00190,map01100 M00417 R11335 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.5 - - COX2,COX_ARM k141_14510_3 1116375.VEJY3_20591 8.75e-188 525.0 COG2084@1|root,COG2084@2|Bacteria,1RA7F@1224|Proteobacteria,1RMMY@1236|Gammaproteobacteria,1XVM6@135623|Vibrionales 135623|Vibrionales H Belongs to the 3-hydroxyisobutyrate dehydrogenase family mmsB - 1.1.1.31 ko:K00020 ko00280,ko01100,map00280,map01100 - R05066 RC00099 ko00000,ko00001,ko01000 - - - NAD_binding_11,NAD_binding_2 k141_14510_4 1116375.VEJY3_20596 1.29e-245 677.0 COG1024@1|root,COG1024@2|Bacteria,1MU0B@1224|Proteobacteria,1RN07@1236|Gammaproteobacteria,1XVZS@135623|Vibrionales 135623|Vibrionales I COG1024 Enoyl-CoA hydratase carnithine racemase - - - - - - - - - - - - ECH_2 k141_14510_5 1116375.VEJY3_20606 8.49e-249 686.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RMMJ@1236|Gammaproteobacteria,1XU1Y@135623|Vibrionales 135623|Vibrionales C COG1960 Acyl-CoA dehydrogenases - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_14510_6 1116375.VEJY3_20611 0.0 919.0 COG1012@1|root,COG1012@2|Bacteria,1MUHV@1224|Proteobacteria,1RNFN@1236|Gammaproteobacteria,1XTUN@135623|Vibrionales 135623|Vibrionales C COG1012 NAD-dependent aldehyde dehydrogenases mmsA - 1.2.1.18,1.2.1.27 ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 M00013 R00705,R00706,R00922,R00935 RC00004,RC02723,RC02817 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_14510_7 1116375.VEJY3_20616 4.83e-260 716.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RM93@1236|Gammaproteobacteria,1XU02@135623|Vibrionales 135623|Vibrionales I Belongs to the thiolase family atoB - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N k141_14510_8 1116375.VEJY3_20621 3.14e-79 236.0 COG0789@1|root,COG0789@2|Bacteria,1RITY@1224|Proteobacteria,1S61S@1236|Gammaproteobacteria,1XXV8@135623|Vibrionales 135623|Vibrionales K transcriptional regulators - - - - - - - - - - - - MerR,MerR-DNA-bind,MerR_1 k141_14510_9 1116375.VEJY3_20626 8.45e-263 722.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RMMJ@1236|Gammaproteobacteria,1XSPG@135623|Vibrionales 135623|Vibrionales C COG1960 Acyl-CoA dehydrogenases liuA - 1.3.8.4 ko:K00253 ko00280,ko01100,map00280,map01100 M00036 R04095 RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_14510_10 1116375.VEJY3_20631 0.0 1002.0 COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,1RNV5@1236|Gammaproteobacteria,1XU22@135623|Vibrionales 135623|Vibrionales I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) liuB - 6.4.1.4 ko:K01969 ko00280,ko01100,map00280,map01100 M00036 R04138 RC00367,RC00942 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans k141_14510_11 1116375.VEJY3_20636 8.82e-167 470.0 COG1024@1|root,COG1024@2|Bacteria,1MVEC@1224|Proteobacteria,1RP85@1236|Gammaproteobacteria,1XT8I@135623|Vibrionales 135623|Vibrionales I COG1024 Enoyl-CoA hydratase carnithine racemase liuC - 4.2.1.18 ko:K13766 ko00280,ko01100,map00280,map01100 M00036 R02085 RC02416 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 k141_14510_12 1116375.VEJY3_20641 2.05e-184 516.0 COG0119@1|root,COG0119@2|Bacteria,1MUMX@1224|Proteobacteria,1RMUX@1236|Gammaproteobacteria,1XU1N@135623|Vibrionales 135623|Vibrionales E COG0119 Isopropylmalate homocitrate citramalate synthases hmgL - 4.1.3.4 ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 M00036,M00088 R01360,R08090 RC00502,RC00503,RC01118,RC01946 ko00000,ko00001,ko00002,ko01000 - - - HMGL-like k141_14510_13 1116375.VEJY3_20646 2.78e-87 261.0 COG5413@1|root,COG5413@2|Bacteria,1NA15@1224|Proteobacteria,1SCSY@1236|Gammaproteobacteria,1XXIV@135623|Vibrionales 135623|Vibrionales S Uncharacterized integral membrane protein (DUF2301) - - - - - - - - - - - - DUF2301 k141_14510_14 1116375.VEJY3_20651 2.39e-195 543.0 COG0697@1|root,COG0697@2|Bacteria,1R7CG@1224|Proteobacteria,1S0XU@1236|Gammaproteobacteria,1XVPK@135623|Vibrionales 135623|Vibrionales EG of the drug metabolite transporter (DMT) superfamily - - - - - - - - - - - - EamA k141_14510_15 1116375.VEJY3_20656 3.33e-245 681.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XUK5@135623|Vibrionales 135623|Vibrionales NT methyl-accepting chemotaxis protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - MCPsignal,PAS_9 k141_14510_16 1116375.VEJY3_21126 4.75e-269 738.0 COG0282@1|root,COG0282@2|Bacteria,1MW61@1224|Proteobacteria,1RMKB@1236|Gammaproteobacteria,1XT0N@135623|Vibrionales 135623|Vibrionales F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction ackA2 GO:0003674,GO:0003824,GO:0006091,GO:0006113,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008776,GO:0009987,GO:0015980,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0044237,GO:0055114 2.7.2.1 ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00315,R01353 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - Acetate_kinase k141_29905_1 1347087.CBYO010000022_gene3591 2.65e-05 46.6 COG1011@1|root,COG1011@2|Bacteria,1TS3W@1239|Firmicutes,4HADE@91061|Bacilli 91061|Bacilli S hydrolase (HAD superfamily) ysaA - 3.1.3.5,3.8.1.2 ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346,R05287 RC00017,RC00697 ko00000,ko00001,ko01000 - - - HAD_2 k141_29905_2 1132442.KB889752_gene3571 8.2e-22 90.9 2ECBP@1|root,336A1@2|Bacteria,1VIYR@1239|Firmicutes,4HPVZ@91061|Bacilli,1ZJA9@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_33505_1 218284.CCDN010000002_gene2181 3.02e-94 295.0 COG1502@1|root,COG1502@2|Bacteria,1VSU5@1239|Firmicutes,4HTP4@91061|Bacilli,1ZJTB@1386|Bacillus 91061|Bacilli I Lamin Tail Domain - - - - - - - - - - - - LTD,PLDc_2 k141_13354_1 997296.PB1_10097 1.3e-21 94.7 29H5Q@1|root,30439@2|Bacteria,1V63Q@1239|Firmicutes,4HHR2@91061|Bacilli,1ZE9T@1386|Bacillus 91061|Bacilli S Nuclease-related domain - - - - - - - - - - - - NERD k141_8563_1 1453501.JELR01000001_gene3101 9.34e-73 222.0 COG0698@1|root,COG0698@2|Bacteria,1MWIB@1224|Proteobacteria,1RPEG@1236|Gammaproteobacteria,465NE@72275|Alteromonadaceae 1236|Gammaproteobacteria G Ribose-5-phosphate isomerase Z012_03465 - 5.3.1.26,5.3.1.6 ko:K01808,ko:K01819 ko00030,ko00051,ko00052,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00052,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01056,R03240,R09030 RC00376,RC00434 ko00000,ko00001,ko00002,ko01000 - - - DUF3666,LacAB_rpiB k141_7390_1 1408303.JNJJ01000088_gene3354 1.08e-77 237.0 COG0726@1|root,COG0726@2|Bacteria,1UYT9@1239|Firmicutes,4HBUH@91061|Bacilli,1ZB7W@1386|Bacillus 91061|Bacilli G Polysaccharide deacetylase - - 3.5.1.41 ko:K01452 ko00520,ko01100,map00520,map01100 - R02333 RC00166,RC00300 ko00000,ko00001,ko01000 - - - Polysacc_deac_1 k141_16880_1 1116375.VEJY3_15385 3.65e-39 137.0 COG0204@1|root,COG0204@2|Bacteria,1MVWG@1224|Proteobacteria,1RR21@1236|Gammaproteobacteria,1XTJU@135623|Vibrionales 135623|Vibrionales I 1-acyl-sn-glycerol-3-phosphate acyltransferase - - - - - - - - - - - - Acyltransferase k141_16880_2 1116375.VEJY3_15390 2.5e-194 543.0 29JMV@1|root,306J6@2|Bacteria,1RDSQ@1224|Proteobacteria,1S492@1236|Gammaproteobacteria,1XU7R@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF2860) - - - - - - - - - - - - DUF2860 k141_16880_3 1116375.VEJY3_15395 3.08e-280 772.0 COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,1RMB9@1236|Gammaproteobacteria,1XTCR@135623|Vibrionales 135623|Vibrionales O ATPase with chaperone activity comM - - ko:K07391 - - - - ko00000 - - - ChlI,Mg_chelatase,Mg_chelatase_C k141_25217_1 218284.CCDN010000010_gene4334 4.29e-58 186.0 COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,4HCFI@91061|Bacilli,1ZCC7@1386|Bacillus 91061|Bacilli J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs truA GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 ko:K06173 - - - - ko00000,ko01000,ko03016 - - - PseudoU_synth_1 k141_14511_1 1294265.JCM21738_4121 2.19e-99 295.0 COG1231@1|root,COG1231@2|Bacteria,1UZBA@1239|Firmicutes,4HC4Q@91061|Bacilli,1ZEMF@1386|Bacillus 91061|Bacilli E Flavin containing amine oxidoreductase - - - - - - - - - - - - Amino_oxidase k141_26493_1 218284.CCDN010000001_gene163 4.9e-123 361.0 COG1271@1|root,COG1271@2|Bacteria,1TRH4@1239|Firmicutes,4HA19@91061|Bacilli,1ZBAG@1386|Bacillus 91061|Bacilli C oxidase, subunit cydA - 1.10.3.14 ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - Cyt_bd_oxida_I k141_22823_2 1453501.JELR01000002_gene1048 2.22e-180 512.0 COG0454@1|root,COG0456@2|Bacteria,1MVZ2@1224|Proteobacteria,1RSC5@1236|Gammaproteobacteria,465P6@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG0456 Acetyltransferases - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10,DUF3335 k141_22823_3 1453501.JELR01000002_gene1033 9.13e-277 766.0 COG0189@1|root,COG0189@2|Bacteria,1MX5X@1224|Proteobacteria,1RNXP@1236|Gammaproteobacteria,464RX@72275|Alteromonadaceae 1236|Gammaproteobacteria HJ Glutathione synthase ribosomal protein S6 modification enzyme (Glutaminyl transferase) - - - - - - - - - - - - Dala_Dala_lig_C,RLAN,RimK k141_22823_4 349521.HCH_03499 1.72e-46 156.0 2DMWM@1|root,32U4H@2|Bacteria,1N2SS@1224|Proteobacteria,1S9T8@1236|Gammaproteobacteria,1XM71@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_22823_5 1279017.AQYJ01000027_gene1723 1.78e-175 493.0 COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,1RPT8@1236|Gammaproteobacteria,465VQ@72275|Alteromonadaceae 1236|Gammaproteobacteria K Transcriptional regulator finR - - - - - - - - - - - HTH_1,LysR_substrate k141_12183_1 1384057.CD33_14170 6.52e-45 151.0 28H7M@1|root,2Z7JU@2|Bacteria,1UG4F@1239|Firmicutes,4HHH8@91061|Bacilli,3IZ5H@400634|Lysinibacillus 91061|Bacilli S phage tail protein - - - - - - - - - - - - - k141_12183_2 1169144.KB910924_gene330 1.7e-36 127.0 2DZ74@1|root,32V6T@2|Bacteria,1VAQV@1239|Firmicutes,4HMMC@91061|Bacilli,1ZIB7@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_12183_3 1121428.DESHY_20147___1 3.29e-66 237.0 COG5283@1|root,COG5283@2|Bacteria,1UHQM@1239|Firmicutes,25E9Q@186801|Clostridia,262NR@186807|Peptococcaceae 186801|Clostridia D TIGRFAM phage tail tape measure protein, TP901 family, core region - - - - - - - - - - - - Peptidase_M23,PhageMin_Tail k141_13355_1 218284.CCDN010000006_gene3543 1.28e-59 191.0 COG0583@1|root,COG0583@2|Bacteria,1TRYW@1239|Firmicutes,4H9T5@91061|Bacilli,1ZC6S@1386|Bacillus 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_13355_2 1042163.BRLA_c025960 1.1e-40 146.0 COG0531@1|root,COG0531@2|Bacteria,1TT8K@1239|Firmicutes,4HCAU@91061|Bacilli,26UVT@186822|Paenibacillaceae 91061|Bacilli E amino acid yecA - - ko:K16263 - - - - ko00000,ko02000 2.A.3.13 - - AA_permease_2 k141_3864_2 1122963.AUHB01000002_gene973 1.09e-60 200.0 COG0582@1|root,COG0582@2|Bacteria,1MXUB@1224|Proteobacteria,2U4UD@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Phage integrase, N-terminal - - - - - - - - - - - - Integrase_1,Phage_int_SAM_2 k141_29906_1 1197906.CAJQ02000029_gene3950 2.47e-24 107.0 COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1MWKS@1224|Proteobacteria,2TQV8@28211|Alphaproteobacteria,3JUGP@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily pheT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - B3_4,B5,FDX-ACB,tRNA_bind k141_28833_1 1307436.PBF_06626 1.42e-06 45.4 29REB@1|root,30CGW@2|Bacteria,1U9VZ@1239|Firmicutes,4IK3R@91061|Bacilli,1ZKD9@1386|Bacillus 91061|Bacilli S SR1 protein - - - - - - - - - - - - SR1P k141_22824_1 218284.CCDN010000006_gene3762 2.24e-92 273.0 COG1999@1|root,COG1999@2|Bacteria,1V03J@1239|Firmicutes,4IBXB@91061|Bacilli,1ZH9Z@1386|Bacillus 91061|Bacilli S SCO1/SenC - - - - - - - - - - - - SCO1-SenC k141_9710_3 279010.BL00759 5.58e-237 660.0 COG1783@1|root,COG1783@2|Bacteria,1TRQP@1239|Firmicutes,4HDMY@91061|Bacilli,1ZCXF@1386|Bacillus 91061|Bacilli S phage terminase, large subunit yqaT - - ko:K06909 - - - - ko00000 - - - Terminase_3,Terminase_3C k141_9710_4 935836.JAEL01000021_gene1501 2.95e-80 248.0 COG5484@1|root,COG5484@2|Bacteria,1V6XI@1239|Firmicutes,4HIZ8@91061|Bacilli,1ZDWD@1386|Bacillus 91061|Bacilli L DNA packaging - - - - - - - - - - - - Phage_terminase,Terminase_5 k141_26538_1 1116375.VEJY3_17501 3.12e-159 451.0 COG0673@1|root,COG0673@2|Bacteria,1MZIG@1224|Proteobacteria,1RS5T@1236|Gammaproteobacteria,1XU2H@135623|Vibrionales 135623|Vibrionales S dehydrogenases and related proteins - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C k141_26538_2 674977.VMC_19300 6.98e-265 732.0 COG0534@1|root,COG0534@2|Bacteria,1MVRV@1224|Proteobacteria,1RRDQ@1236|Gammaproteobacteria,1XSZX@135623|Vibrionales 135623|Vibrionales V COG0534 Na -driven multidrug efflux pump VVA1228 - - - - - - - - - - - MatE k141_26538_3 1116375.VEJY3_23021 2.7e-237 656.0 COG1448@1|root,COG1448@2|Bacteria,1MUT0@1224|Proteobacteria,1RN02@1236|Gammaproteobacteria,1Y01E@135623|Vibrionales 135623|Vibrionales E Aminotransferase class I and II - - 2.6.1.57 ko:K00832 ko00270,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 M00024,M00025,M00034,M00040 R00694,R00734,R01731,R07396,R10845 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k141_10936_2 1116375.VEJY3_03675 4.65e-185 517.0 COG1090@1|root,COG1090@2|Bacteria,1MUB4@1224|Proteobacteria,1RN6A@1236|Gammaproteobacteria,1XSDX@135623|Vibrionales 135623|Vibrionales S nucleoside-diphosphate sugar epimerase yfcH - - ko:K07071 - - - - ko00000 - - - DUF1731,Epimerase k141_29924_2 218284.CCDN010000001_gene1188 4.48e-71 218.0 2CFTY@1|root,336V6@2|Bacteria,1VH1W@1239|Firmicutes,4HQI3@91061|Bacilli,1ZH6G@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_29924_3 218284.CCDN010000001_gene1187 1.47e-71 231.0 COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,4HA2X@91061|Bacilli,1ZCFH@1386|Bacillus 91061|Bacilli F Belongs to the formate--tetrahydrofolate ligase family fhs GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.3 ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R00943 RC00026,RC00111 ko00000,ko00001,ko00002,ko01000 - - - FTHFS k141_22861_1 218284.CCDN010000007_gene3940 2.47e-126 369.0 COG1078@1|root,COG1078@2|Bacteria,1TPVB@1239|Firmicutes,4HAX8@91061|Bacilli,1ZBRB@1386|Bacillus 91061|Bacilli S COG1078 HD superfamily phosphohydrolases ywfO GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 - ko:K06885 - - - - ko00000 - - - HD k141_25234_1 223926.28809179 6.5e-148 436.0 COG2199@1|root,COG2199@2|Bacteria,1RGCV@1224|Proteobacteria,1T259@1236|Gammaproteobacteria,1XU5C@135623|Vibrionales 135623|Vibrionales T Periplasmic sensor domain - - - - - - - - - - - - CHASE8,GGDEF,HAMP,PAS,PAS_8,PAS_9 k141_35871_3 991905.SL003B_1509 5.77e-44 146.0 2CK8Q@1|root,31PVK@2|Bacteria,1RIRH@1224|Proteobacteria,2U9HH@28211|Alphaproteobacteria,4BQRR@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_35871_4 991905.SL003B_1510 1.83e-34 125.0 2CBAE@1|root,32YK1@2|Bacteria,1N7NP@1224|Proteobacteria,2UH5V@28211|Alphaproteobacteria,4BR0B@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_35871_5 1515746.HR45_16150 2.23e-145 410.0 2E6F8@1|root,3312N@2|Bacteria,1NPJ2@1224|Proteobacteria,1SP6Y@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_19482_2 99598.Cal7507_2137 5.39e-18 84.3 COG3247@1|root,COG3247@2|Bacteria,1G88W@1117|Cyanobacteria,1HN6U@1161|Nostocales 1117|Cyanobacteria S Short repeat of unknown function (DUF308) - - - - - - - - - - - - DUF308 k141_15879_1 1217720.ALOX01000052_gene1514 5.39e-80 262.0 COG0025@1|root,COG0025@2|Bacteria,1MW5T@1224|Proteobacteria,2TSHB@28211|Alphaproteobacteria,2JR4X@204441|Rhodospirillales 204441|Rhodospirillales P Sodium/hydrogen exchanger family - - - ko:K03316 - - - - ko00000 2.A.36 - - Na_H_Exchanger k141_23158_1 552525.B5LPN4_9CAUD 1.02e-16 76.6 4QAR6@10239|Viruses,4QUTK@35237|dsDNA viruses no RNA stage,4QPS2@28883|Caudovirales,4QKTM@10699|Siphoviridae 10699|Siphoviridae S dUTPase - GO:0003674,GO:0003824,GO:0004170,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0047429 - - - - - - - - - - - k141_34920_1 1453501.JELR01000002_gene535 2.58e-106 320.0 COG1162@1|root,COG1162@2|Bacteria,1MUEF@1224|Proteobacteria,1RMMB@1236|Gammaproteobacteria,465K2@72275|Alteromonadaceae 1236|Gammaproteobacteria S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit rsgA2 - 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 - R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 - - - RsgA_GTPase k141_25481_1 218284.CCDN010000001_gene1822 7.54e-104 313.0 COG1966@1|root,COG1966@2|Bacteria,1TQN8@1239|Firmicutes,4H9SU@91061|Bacilli,1ZC6K@1386|Bacillus 91061|Bacilli T Carbon starvation protein cstA_2 - - - - - - - - - - - CstA,CstA_5TM k141_600_1 218284.CCDN010000001_gene1804 0.0 1137.0 COG2366@1|root,COG2366@2|Bacteria,1UFHA@1239|Firmicutes,4HACM@91061|Bacilli,1ZCMT@1386|Bacillus 91061|Bacilli S Penicillin amidase acyII - 3.5.1.11 ko:K01434 ko00311,ko01130,map00311,map01130 - R02170 RC00166,RC00328 ko00000,ko00001,ko01000,ko01002 - - - Penicil_amidase k141_2798_1 1384049.CD29_03675 4.54e-51 166.0 COG2335@1|root,COG2335@2|Bacteria,1VDJ1@1239|Firmicutes,4HG07@91061|Bacilli 91061|Bacilli M Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - - - - - - - - - - Fasciclin k141_30072_1 1499680.CCFE01000024_gene3009 7.93e-41 144.0 COG1744@1|root,COG1744@2|Bacteria,1UY2H@1239|Firmicutes,4HCI5@91061|Bacilli,1ZBN4@1386|Bacillus 91061|Bacilli S Transcriptional activator protein med med - - ko:K05519,ko:K07335 - - - - ko00000,ko03000 - - - Bmp k141_31327_1 42565.FP66_11060 1.87e-74 230.0 COG0613@1|root,COG0613@2|Bacteria,1MWIH@1224|Proteobacteria,1RNCG@1236|Gammaproteobacteria,1XJX3@135619|Oceanospirillales 135619|Oceanospirillales S metal-dependent phosphoesterases (PHP family) - - 3.1.3.97 ko:K07053 - - R00188,R11188 RC00078 ko00000,ko01000 - - - PHP k141_31327_2 42565.FP66_11055 8.38e-27 99.4 COG2350@1|root,COG2350@2|Bacteria,1MZ9Z@1224|Proteobacteria,1S8UC@1236|Gammaproteobacteria,1XKEK@135619|Oceanospirillales 135619|Oceanospirillales S YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the yciI - - ko:K09780 - - - - ko00000 - - - YCII k141_1592_2 1294265.JCM21738_3562 1.8e-34 122.0 2DSIK@1|root,33GA6@2|Bacteria,1VN6K@1239|Firmicutes,4HSJR@91061|Bacilli,1ZHV5@1386|Bacillus 91061|Bacilli S TATA-box binding ywmB - - - - - - - - - - - DUF1779 k141_36024_1 1121271.AUCM01000008_gene3300 7.97e-45 166.0 28JJU@1|root,2Z9CS@2|Bacteria,1MYM2@1224|Proteobacteria,2U332@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_12523_1 1116375.VEJY3_14095 0.000127 43.1 COG0137@1|root,COG0137@2|Bacteria,1MV0Y@1224|Proteobacteria,1RMEC@1236|Gammaproteobacteria,1XU2D@135623|Vibrionales 135623|Vibrionales F Belongs to the argininosuccinate synthase family. Type 1 subfamily argG GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 M00029,M00844,M00845 R01954 RC00380,RC00629 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Arginosuc_synth k141_12523_2 1116375.VEJY3_14100 1.14e-120 348.0 COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,1RNKK@1236|Gammaproteobacteria,1XSF2@135623|Vibrionales 135623|Vibrionales F Belongs to the acetylglutamate kinase family. ArgB subfamily argB GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R02649 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase k141_8841_1 35841.BT1A1_3006 4.61e-27 108.0 2BZRV@1|root,2Z8AV@2|Bacteria,1UX40@1239|Firmicutes,4HAVP@91061|Bacilli,1ZDM4@1386|Bacillus 91061|Bacilli S Nuclease-related domain - - - - - - - - - - - - NERD k141_6468_2 218284.CCDN010000001_gene1501 3.92e-88 259.0 COG0824@1|root,COG0824@2|Bacteria,1VAGM@1239|Firmicutes,4HIVC@91061|Bacilli,1ZG6C@1386|Bacillus 91061|Bacilli S thioesterase yneP - - ko:K07107 - - - - ko00000,ko01000 - - - 4HBT,4HBT_2 k141_601_1 272558.10173559 3.89e-10 58.2 COG1396@1|root,COG1396@2|Bacteria 2|Bacteria K sequence-specific DNA binding - - - - - - - - - - - - HTH_3,HTH_31 k141_34921_1 1395571.TMS3_0118830 1.12e-58 191.0 COG3063@1|root,COG3063@2|Bacteria,1RD9T@1224|Proteobacteria,1S3R3@1236|Gammaproteobacteria 1236|Gammaproteobacteria NU COG0457 FOG TPR repeat - - - - - - - - - - - - TPR_19,TPR_2,TPR_8 k141_7549_1 935836.JAEL01000021_gene1543 1.68e-125 368.0 COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,4H9VI@91061|Bacilli,1ZB6B@1386|Bacillus 91061|Bacilli G Belongs to the GPI family pgi GO:0003674,GO:0003824,GO:0004347,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGI k141_12557_1 1279017.AQYJ01000027_gene1558 2.1e-38 150.0 COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,1SKYM@1236|Gammaproteobacteria,4665R@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG3209 Rhs family protein - - - - - - - - - - - - RHS_repeat k141_20639_1 218284.CCDN010000001_gene1283 3.89e-54 178.0 COG0547@1|root,COG0547@2|Bacteria,1TP8U@1239|Firmicutes,4H9KQ@91061|Bacilli,1ZBZ1@1386|Bacillus 91061|Bacilli E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) trpD GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0004425,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R00985,R00986,R01073 RC00010,RC00440,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Glycos_trans_3N,Glycos_transf_3 k141_20639_2 218284.CCDN010000001_gene1284 1.11e-81 248.0 COG0134@1|root,COG0134@2|Bacteria,1TR94@1239|Firmicutes,4HDZQ@91061|Bacilli,1ZD63@1386|Bacillus 91061|Bacilli E Belongs to the TrpC family trpC GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48,5.3.1.24 ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03508,R03509 RC00944,RC00945 ko00000,ko00001,ko00002,ko01000 - - - IGPS k141_17096_1 218284.CCDN010000004_gene3137 0.000111 43.9 COG0702@1|root,COG0702@2|Bacteria,1TS7J@1239|Firmicutes,4HFT3@91061|Bacilli,1ZGA3@1386|Bacillus 91061|Bacilli GM NAD(P)H-binding yheG - - - - - - - - - - - NAD_binding_10 k141_25508_1 374526.A5GYP7_9CAUD 9.83e-48 158.0 4QAKE@10239|Viruses,4QPCE@28883|Caudovirales 28883|Caudovirales S endonuclease activity - - - - - - - - - - - - - k141_5277_1 42565.FP66_00220 3.43e-101 307.0 COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,1RMD6@1236|Gammaproteobacteria,1XHNY@135619|Oceanospirillales 135619|Oceanospirillales M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan murE - 6.3.2.13 ko:K01928 ko00300,ko00550,map00300,map00550 - R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M k141_15894_1 1042377.AFPJ01000004_gene367 1.26e-18 82.4 COG1664@1|root,COG1664@2|Bacteria,1ND4H@1224|Proteobacteria,1SF92@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Polymer-forming cytoskeletal - - - - - - - - - - - - Bactofilin k141_21874_1 218284.CCDN010000001_gene602 7.98e-175 491.0 COG0181@1|root,COG0181@2|Bacteria,1TPFQ@1239|Firmicutes,4H9TV@91061|Bacilli,1ZCR0@1386|Bacillus 91061|Bacilli H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps hemC GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00084 RC02317 ko00000,ko00001,ko00002,ko01000 - - - Porphobil_deam,Porphobil_deamC k141_21874_2 1501230.ET33_22125 7.94e-14 73.2 COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,1TQNH@1239|Firmicutes,4HBB7@91061|Bacilli,26R9W@186822|Paenibacillaceae 91061|Bacilli H Belongs to the precorrin methyltransferase family hemX - 2.1.1.107,4.2.1.75 ko:K02303,ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R03165,R03194 RC00003,RC00871,RC01861 ko00000,ko00001,ko00002,ko01000 - - - HEM4,TP_methylase k141_37252_2 1123401.JHYQ01000031_gene3389 1.17e-13 72.4 COG1721@1|root,COG1721@2|Bacteria,1MXDI@1224|Proteobacteria,1RQSS@1236|Gammaproteobacteria 1236|Gammaproteobacteria S conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - - - - - - - - - - DUF58 k141_36042_2 511062.GU3_11715 1.64e-07 56.6 COG0508@1|root,COG0508@2|Bacteria,1MUGY@1224|Proteobacteria,1RPKE@1236|Gammaproteobacteria 1236|Gammaproteobacteria C 2-oxoacid dehydrogenases acyltransferase (catalytic domain) - - 2.3.1.12 ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding k141_625_1 1307436.PBF_05713 8.25e-78 253.0 COG0840@1|root,COG0840@2|Bacteria,1TZ8Z@1239|Firmicutes,4HBMM@91061|Bacilli,1ZDNK@1386|Bacillus 91061|Bacilli NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). mcp4 - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal k141_12558_1 218284.CCDN010000001_gene202 5.59e-36 124.0 2AQNN@1|root,31FW1@2|Bacteria,1UA6S@1239|Firmicutes,4IKHR@91061|Bacilli,1ZH0V@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_20640_2 218284.CCDN010000002_gene2367 1.27e-43 143.0 2CG6R@1|root,2ZSDD@2|Bacteria,1W1VA@1239|Firmicutes,4I0TI@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - k141_8862_1 42565.FP66_00935 3.14e-102 296.0 COG2193@1|root,COG2193@2|Bacteria,1RD4Y@1224|Proteobacteria,1S40G@1236|Gammaproteobacteria,1XJQH@135619|Oceanospirillales 135619|Oceanospirillales P Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex - - 1.16.3.1 ko:K03594 ko00860,map00860 - R00078 RC02758 ko00000,ko00001,ko01000 - - - Ferritin k141_24180_1 218284.CCDN010000007_gene3928 2.4e-49 159.0 2DQIA@1|root,3371K@2|Bacteria,1VHCJ@1239|Firmicutes,4HMJ4@91061|Bacilli,1ZR81@1386|Bacillus 91061|Bacilli S Heat induced stress protein YflT - - - - - - - - - - - - YflT k141_24180_2 218284.CCDN010000007_gene3927 2.43e-155 439.0 COG0351@1|root,COG0351@2|Bacteria,1TQ4A@1239|Firmicutes,4H9PP@91061|Bacilli,1ZQ7W@1386|Bacillus 91061|Bacilli H Phosphomethylpyrimidine kinase pdxK - 2.7.1.35 ko:K00868 ko00750,ko01100,map00750,map01100 - R00174,R01909,R02493 RC00002,RC00017 ko00000,ko00001,ko01000 - - iSB619.SA_RS03115 Phos_pyr_kin k141_13698_1 218284.CCDN010000006_gene3596 9.33e-106 318.0 COG2132@1|root,COG2132@2|Bacteria,1TQJK@1239|Firmicutes,4IRUW@91061|Bacilli,1ZBEQ@1386|Bacillus 91061|Bacilli Q Multi-copper - - - - - - - - - - - - Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3,Cupredoxin_1 k141_23170_5 1116375.VEJY3_08100 0.0 1191.0 COG3598@1|root,COG3598@2|Bacteria,1PDA3@1224|Proteobacteria,1T98R@1236|Gammaproteobacteria,1Y1M3@135623|Vibrionales 135623|Vibrionales L Psort location Cytoplasmic, score - - - - - - - - - - - - - k141_23170_8 1116375.VEJY3_08110 1.19e-95 280.0 COG2963@1|root,COG2963@2|Bacteria,1N24I@1224|Proteobacteria,1SQN3@1236|Gammaproteobacteria 1236|Gammaproteobacteria L transposase activity - - - - - - - - - - - - - k141_23170_10 1123322.KB904677_gene3138 1.48e-64 213.0 COG1403@1|root,COG1403@2|Bacteria,2IINJ@201174|Actinobacteria 201174|Actinobacteria V HNH endonuclease - - - ko:K07451 - - - - ko00000,ko01000,ko02048 - - - - k141_2820_1 1042377.AFPJ01000036_gene1144 8.42e-85 264.0 COG1757@1|root,COG1757@2|Bacteria,1MY5C@1224|Proteobacteria,1RP6I@1236|Gammaproteobacteria,465EF@72275|Alteromonadaceae 1236|Gammaproteobacteria C Na H antiporter mleN - - - - - - - - - - - Na_H_antiporter k141_7563_1 324057.Pjdr2_2434 5.51e-12 65.5 COG4347@1|root,COG4347@2|Bacteria,1V1NI@1239|Firmicutes,4HFTW@91061|Bacilli,26X54@186822|Paenibacillaceae 91061|Bacilli S Protein of unknown function (DUF1405) ypjA - - - - - - - - - - - DUF1405 k141_7563_2 218284.CCDN010000001_gene1126 3.79e-120 347.0 COG1290@1|root,COG2010@1|root,COG1290@2|Bacteria,COG2010@2|Bacteria,1TRS8@1239|Firmicutes,4H9XH@91061|Bacilli,1ZCZW@1386|Bacillus 91061|Bacilli C Menaquinol-cytochrome c reductase cytochrome b c subunit qcrC - - ko:K03888 ko00190,ko01100,map00190,map01100 M00151 - - ko00000,ko00001,ko00002 - - - Cytochrom_B_C,Cytochrome_CBB3 k141_19504_1 218284.CCDN010000006_gene3662 2.34e-159 457.0 COG0168@1|root,COG0168@2|Bacteria,1TQ4S@1239|Firmicutes,4H9ME@91061|Bacilli,1ZBJ9@1386|Bacillus 91061|Bacilli P Potassium ktrB_3 - - ko:K03498 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkH k141_5278_2 1042377.AFPJ01000012_gene1386 1.3e-36 124.0 2DQ1B@1|root,334B6@2|Bacteria,1NCBI@1224|Proteobacteria,1SCWY@1236|Gammaproteobacteria,468ZR@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF2909) - - - - - - - - - - - - DUF2909 k141_28981_1 1219076.N646_1395 1e-107 333.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RPM5@1236|Gammaproteobacteria,1XTG6@135623|Vibrionales 135623|Vibrionales I COG1960 Acyl-CoA dehydrogenases fadE - - ko:K06445 ko00071,ko01100,ko01212,map00071,map01100,map01212 M00087 R01175,R01279,R03777,R03857,R03990,R04751,R04754 RC00052,RC00076 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_N,DUF1974 k141_28981_2 223926.28807283 0.0 992.0 COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,1SYC8@1236|Gammaproteobacteria,1XVG3@135623|Vibrionales 135623|Vibrionales U Sulfate permease family - - - - - - - - - - - - STAS,Sulfate_transp k141_11234_1 1042163.BRLA_c041450 1.69e-09 54.3 2CDFK@1|root,2Z8BH@2|Bacteria,1V43D@1239|Firmicutes,4HY70@91061|Bacilli 91061|Bacilli S DNA N-6-adenine-methyltransferase (Dam) - - - - - - - - - - - - Dam k141_11234_2 1007103.AFHW01000034_gene2001 1.87e-45 160.0 COG1484@1|root,COG1484@2|Bacteria,1VCHX@1239|Firmicutes,4HKZ7@91061|Bacilli,26XAA@186822|Paenibacillaceae 91061|Bacilli L DNA-dependent DNA replication - - - ko:K02315 - - - - ko00000,ko03032 - - - IstB_IS21 k141_18388_1 272558.10174714 1.54e-26 102.0 28IW6@1|root,2Z8UG@2|Bacteria,1TSGG@1239|Firmicutes,4HCTI@91061|Bacilli,1ZBNE@1386|Bacillus 91061|Bacilli S YvbH-like oligomerisation region yvbH - - - - - - - - - - - YvbH_ext,bPH_1 k141_18388_2 1121090.KB894717_gene3236 1.17e-19 82.8 29KSU@1|root,307QA@2|Bacteria,1U219@1239|Firmicutes,4IBI3@91061|Bacilli,1ZGUK@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_30092_1 218284.CCDN010000001_gene105 1.03e-183 518.0 COG3480@1|root,COG3480@2|Bacteria,1TRUF@1239|Firmicutes,4HBAY@91061|Bacilli,1ZAW6@1386|Bacillus 91061|Bacilli T Belongs to the peptidase S16 family ylbL - - ko:K07177 ko02024,map02024 - - - ko00000,ko00001,ko01002 - - - Lon_C,PDZ_2 k141_36043_1 1453501.JELR01000002_gene108 7.83e-103 319.0 COG3591@1|root,COG3591@2|Bacteria,1MX71@1224|Proteobacteria,1RRGG@1236|Gammaproteobacteria,465PD@72275|Alteromonadaceae 1236|Gammaproteobacteria E Peptidase S46 - - - - - - - - - - - - Peptidase_S46 k141_18389_1 218284.CCDN010000001_gene1718 6.69e-97 288.0 COG1366@1|root,COG1366@2|Bacteria,1VV9B@1239|Firmicutes,4HVUI@91061|Bacilli,1ZIEV@1386|Bacillus 91061|Bacilli T Belongs to the anti-sigma-factor antagonist family - - - - - - - - - - - - STAS k141_19505_2 218284.CCDN010000005_gene3276 3.17e-28 103.0 2EHZE@1|root,33BQW@2|Bacteria,1VEVS@1239|Firmicutes,4HR6T@91061|Bacilli,1ZJXP@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_27670_1 458817.Shal_2185 3.41e-227 647.0 COG4694@1|root,COG4694@2|Bacteria,1PRHR@1224|Proteobacteria,1RWYP@1236|Gammaproteobacteria,2QEEH@267890|Shewanellaceae 1236|Gammaproteobacteria S AAA domain - - - - - - - - - - - - AAA_13 k141_31341_1 218284.CCDN010000001_gene661 6.36e-211 603.0 COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,1TQVT@1239|Firmicutes,4HB6K@91061|Bacilli,1ZBS9@1386|Bacillus 91061|Bacilli U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secD GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD_SecF,Sec_GG k141_23171_1 218284.CCDN010000001_gene1035 9.84e-105 306.0 COG1300@1|root,COG1300@2|Bacteria,1V81P@1239|Firmicutes,4HJW8@91061|Bacilli,1ZAYC@1386|Bacillus 91061|Bacilli S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane spoIIM GO:0005575,GO:0005623,GO:0008150,GO:0010564,GO:0022603,GO:0030428,GO:0032465,GO:0032467,GO:0032954,GO:0042173,GO:0043937,GO:0044087,GO:0044089,GO:0044464,GO:0045595,GO:0045787,GO:0048518,GO:0048522,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051130,GO:0051302,GO:0051726,GO:0051781,GO:0065007,GO:0090068,GO:1901891,GO:1901893 - ko:K06384 - - - - ko00000 - - - SpoIIM k141_33814_1 218284.CCDN010000002_gene2728 3.68e-69 209.0 2AQDK@1|root,31FJY@2|Bacteria,1UA3D@1239|Firmicutes,4IKD2@91061|Bacilli,1ZGHI@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_8864_1 218284.CCDN010000008_gene4188 4.43e-87 267.0 COG2081@1|root,COG2081@2|Bacteria,1TQ6E@1239|Firmicutes,4HAAT@91061|Bacilli,1ZAT3@1386|Bacillus 91061|Bacilli S HI0933-like protein ytfP - - ko:K07007 - - - - ko00000 - - - HI0933_like k141_15896_1 935837.JAEK01000063_gene3983 3.4e-10 61.6 28I0M@1|root,2Z85B@2|Bacteria,1TTBC@1239|Firmicutes,4HENN@91061|Bacilli,1ZCDZ@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3231) - - - - - - - - - - - - DUF3231 k141_15896_2 1294265.JCM21738_484 2.24e-65 199.0 COG0726@1|root,COG0726@2|Bacteria 2|Bacteria G polysaccharide deacetylase - - 3.2.1.8 ko:K01181 - - - - ko00000,ko01000 - - - Cadherin_3,Glyco_hydro_11,Polysacc_deac_1,SLH k141_37255_1 218284.CCDN010000010_gene4394 8.71e-165 483.0 COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HACY@91061|Bacilli,1ZB4C@1386|Bacillus 91061|Bacilli O Belongs to the ClpA ClpB family clpC GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 - ko:K03696 ko01100,map01100 - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N,UVR k141_25509_3 1279017.AQYJ01000029_gene3793 2.26e-51 172.0 COG2515@1|root,COG2515@2|Bacteria,1MVYF@1224|Proteobacteria,1RMYP@1236|Gammaproteobacteria,4670H@72275|Alteromonadaceae 1236|Gammaproteobacteria E Pyridoxal-phosphate dependent enzyme - - 4.4.1.15 ko:K05396 ko00270,map00270 - R01874 RC00382 ko00000,ko00001,ko01000 - - - PALP k141_2821_1 1219076.N646_2772 1.59e-187 531.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,1RMT8@1236|Gammaproteobacteria,1XT7Z@135623|Vibrionales 135623|Vibrionales F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth guaB - 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 - - - CBS,IMPDH k141_30093_1 42565.FP66_15860 1.22e-08 54.7 COG0418@1|root,COG0418@2|Bacteria,1MUYP@1224|Proteobacteria,1RNEN@1236|Gammaproteobacteria,1XII3@135619|Oceanospirillales 135619|Oceanospirillales F Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate pyrC - 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 k141_26859_1 1134474.O59_000161 1.24e-63 218.0 COG1629@1|root,COG1629@2|Bacteria,1MV8W@1224|Proteobacteria,1RQEQ@1236|Gammaproteobacteria,1FI5Y@10|Cellvibrio 1236|Gammaproteobacteria P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec k141_23172_1 218284.CCDN010000004_gene3150 5.88e-83 258.0 COG0189@1|root,COG0189@2|Bacteria,1UZ79@1239|Firmicutes,4HTI1@91061|Bacilli,1ZBQZ@1386|Bacillus 91061|Bacilli HJ COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase) - - - - - - - - - - - - ATPgrasp_YheCD k141_17098_2 218284.CCDN010000006_gene3523 4.74e-62 200.0 COG4114@1|root,COG4114@2|Bacteria,1V28K@1239|Firmicutes,4HGQ8@91061|Bacilli,1ZB7Y@1386|Bacillus 91061|Bacilli S FhuF 2Fe-2S C-terminal domain - - - - - - - - - - - - FhuF,FhuF_C k141_18391_1 218284.CCDN010000002_gene2109 6.02e-104 313.0 COG1249@1|root,COG1249@2|Bacteria,1UYJP@1239|Firmicutes,4HCWF@91061|Bacilli,1ZED9@1386|Bacillus 91061|Bacilli C Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain - - 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyr_redox_2,Pyr_redox_dim k141_26864_1 1042377.AFPJ01000022_gene1300 7.86e-28 112.0 COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,1RMWN@1236|Gammaproteobacteria,465G2@72275|Alteromonadaceae 1236|Gammaproteobacteria C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family nasA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K00372 ko00910,ko01120,map00910,map01120 M00531 R00798,R01106 RC02812 ko00000,ko00001,ko00002,ko01000 - - - Fer2_BFD,Molybdop_Fe4S4,Molybdopterin,Molydop_binding k141_26864_2 1042377.AFPJ01000022_gene1299 2.08e-189 539.0 COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,1RMQU@1236|Gammaproteobacteria,4662Y@72275|Alteromonadaceae 1236|Gammaproteobacteria H COG0303 Molybdopterin biosynthesis enzyme moeA - 2.10.1.1 ko:K03750 ko00790,ko01100,map00790,map01100 - R09735 RC03462 ko00000,ko00001,ko01000 - - - MoCF_biosynth,MoeA_C,MoeA_N k141_26864_3 1219065.VPR01S_13_00290 8.63e-43 144.0 COG0346@1|root,COG0346@2|Bacteria,1RHD4@1224|Proteobacteria,1SB56@1236|Gammaproteobacteria,1XXBI@135623|Vibrionales 135623|Vibrionales E COG0346 Lactoylglutathione lyase and related lyases - - - - - - - - - - - - Glyoxalase k141_26864_4 1453501.JELR01000002_gene394 1.48e-119 348.0 COG0412@1|root,COG0412@2|Bacteria,1RCWF@1224|Proteobacteria,1RY38@1236|Gammaproteobacteria,46D0F@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Dienelactone hydrolase family - - - - - - - - - - - - DLH k141_26864_5 1137799.GZ78_07160 2.36e-34 119.0 COG2329@1|root,COG2329@2|Bacteria,1N078@1224|Proteobacteria,1SA3S@1236|Gammaproteobacteria,1XQMF@135619|Oceanospirillales 135619|Oceanospirillales C Antibiotic biosynthesis monooxygenase - - - - - - - - - - - - ABM k141_26864_6 1279017.AQYJ01000028_gene2534 4.09e-65 202.0 COG0789@1|root,COG0789@2|Bacteria,1RH2U@1224|Proteobacteria,1S6M0@1236|Gammaproteobacteria,467FC@72275|Alteromonadaceae 1236|Gammaproteobacteria K helix_turn_helix, mercury resistance soxR GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0044424,GO:0044464,GO:0048037,GO:0050896,GO:0051536,GO:0051537,GO:0051540 - ko:K13639 - - - - ko00000,ko03000 - - - MerR,MerR-DNA-bind,MerR_1 k141_26864_8 913325.N799_09225 8.52e-166 470.0 COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,1RMC5@1236|Gammaproteobacteria,1X36N@135614|Xanthomonadales 135614|Xanthomonadales V Multidrug ABC transporter ATP-binding protein - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_26864_10 1279017.AQYJ01000028_gene2525 8.07e-151 431.0 COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,1RYRB@1236|Gammaproteobacteria,46479@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0491 Zn-dependent hydrolases, including glyoxylases - - - - - - - - - - - - Lactamase_B k141_26864_11 1347087.CBYO010000007_gene1034 6.09e-17 89.4 COG0584@1|root,COG0584@2|Bacteria,1UGF1@1239|Firmicutes,4H9QE@91061|Bacilli 91061|Bacilli C glycerophosphoryl diester phosphodiesterase glpQ - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - GDPD k141_26864_12 1485545.JQLW01000007_gene826 1.44e-44 152.0 28I6Z@1|root,2Z89U@2|Bacteria,1R8YM@1224|Proteobacteria 1224|Proteobacteria S von Willebrand factor (vWF) type A domain - - - - - - - - - - - - - k141_32641_1 218284.CCDN010000001_gene1490 2.67e-80 256.0 COG0187@1|root,COG0187@2|Bacteria,1TQCF@1239|Firmicutes,4H9UC@91061|Bacilli,1ZBMM@1386|Bacillus 91061|Bacilli L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parE GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 - ko:K02622 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim k141_11493_1 1042377.AFPJ01000028_gene2188 1.17e-85 259.0 COG3108@1|root,COG3108@2|Bacteria,1N3XU@1224|Proteobacteria,1SQF8@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Peptidase M15 - - - - - - - - - - - - Peptidase_M15_3 k141_11493_2 1042377.AFPJ01000028_gene2189 2.38e-93 280.0 COG3108@1|root,COG3108@2|Bacteria,1NDQH@1224|Proteobacteria,1T130@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Peptidase M15 - - - - - - - - - - - - Peptidase_M15_3 k141_12752_1 290397.Adeh_0645 4.12e-18 90.9 COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,42MKN@68525|delta/epsilon subdivisions,2WJV6@28221|Deltaproteobacteria,2YTV4@29|Myxococcales 28221|Deltaproteobacteria U type IV pilus secretin PilQ pilQ - - ko:K02666 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - AMIN,STN,Secretin,Secretin_N k141_7711_1 1294265.JCM21738_204 5.52e-13 63.2 2ETAH@1|root,33KUF@2|Bacteria,1VNRP@1239|Firmicutes,4HRRR@91061|Bacilli,1ZKDN@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - CoxIIa k141_30226_2 1453501.JELR01000001_gene2693 1.91e-149 431.0 COG0845@1|root,COG0845@2|Bacteria,1MW65@1224|Proteobacteria,1RRHG@1236|Gammaproteobacteria,465HC@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - - - - - - - - - - Biotin_lipoyl_2,HlyD_D23 k141_30226_3 1121937.AUHJ01000017_gene2985 6.42e-111 330.0 COG3713@1|root,COG4704@1|root,COG3713@2|Bacteria,COG4704@2|Bacteria 2|Bacteria M MltA-interacting MipA family protein mipA - - ko:K07274 - - - - ko00000,ko02000 9.B.99.1 - - DUF2141,MipA k141_22040_1 5147.XP_003346465.1 3.93e-11 64.7 COG0015@1|root,KOG2700@2759|Eukaryota,38D20@33154|Opisthokonta,3NU0G@4751|Fungi,3QMUU@4890|Ascomycota,21682@147550|Sordariomycetes,3U71V@5139|Sordariales,3UM2D@5148|Sordariaceae 4751|Fungi F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily ADE13 GO:0003674,GO:0003824,GO:0004018,GO:0006082,GO:0006106,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 - - - ADSL_C,Lyase_1 k141_22040_2 59374.Fisuc_1873 2.3e-38 134.0 COG0041@1|root,COG0041@2|Bacteria 2|Bacteria F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) purE - 5.4.99.18 ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07405 RC01947 ko00000,ko00001,ko00002,ko01000 - - - AIRC k141_22040_3 1131269.AQVV01000012_gene2599 1.22e-41 148.0 COG0005@1|root,COG0005@2|Bacteria 2|Bacteria F purine-nucleoside phosphorylase activity mtnP - 2.4.2.28 ko:K00772 ko00270,ko01100,map00270,map01100 M00034 R01402 RC00063,RC02819 ko00000,ko00001,ko00002,ko01000 - - - PNP_UDP_1 k141_14843_1 218284.CCDN010000001_gene990 6.73e-244 687.0 COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,1TQAD@1239|Firmicutes,4H9QB@91061|Bacilli,1ZCKD@1386|Bacillus 91061|Bacilli I COG1884 Methylmalonyl-CoA mutase, N-terminal domain subunit mutB - 5.4.99.2 ko:K01847 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00373,M00376,M00741 R00833 RC00395 ko00000,ko00001,ko00002,ko01000 - - - B12-binding,MM_CoA_mutase k141_18635_1 218284.CCDN010000001_gene1956 7.85e-135 390.0 COG2718@1|root,COG2718@2|Bacteria,1TQIN@1239|Firmicutes,4HBIH@91061|Bacilli,1ZATH@1386|Bacillus 91061|Bacilli S Belongs to the UPF0229 family yhbH - - ko:K09786 - - - - ko00000 - - - DUF444 k141_35208_1 1294265.JCM21738_1179 3.32e-41 136.0 COG4224@1|root,COG4224@2|Bacteria,1VEKJ@1239|Firmicutes,4HNIB@91061|Bacilli,1ZIU8@1386|Bacillus 91061|Bacilli S UPF0291 protein ynzC - - - - - - - - - - - DUF896 k141_35208_2 1294265.JCM21738_1178 8.82e-08 51.2 COG0021@1|root,COG0021@2|Bacteria,1TPIB@1239|Firmicutes,4HADA@91061|Bacilli,1ZBQ6@1386|Bacillus 91061|Bacilli G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate tkt - 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C,Transketolase_N k141_27080_1 218284.CCDN010000002_gene2185 2.97e-124 360.0 COG2130@1|root,COG2130@2|Bacteria,1TQUE@1239|Firmicutes,4HCHY@91061|Bacilli,1ZC4N@1386|Bacillus 91061|Bacilli S N-terminal domain of oxidoreductase yfmJ - - ko:K07119 - - - - ko00000 - - - ADH_N_2,ADH_zinc_N k141_27080_2 218284.CCDN010000002_gene2184 2.09e-19 86.3 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli,1ZAXK@1386|Bacillus 91061|Bacilli C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively aldA - 1.2.1.21,1.2.1.22 ko:K07248 ko00620,ko00630,ko01120,map00620,map00630,map01120 - R00203,R01333,R01446 RC00080,RC00104,RC00242 ko00000,ko00001,ko01000 - - - Aldedh k141_33987_1 1517681.HW45_22565 4.21e-204 587.0 COG1298@1|root,COG1298@2|Bacteria,1MUF3@1224|Proteobacteria,1RMSM@1236|Gammaproteobacteria,1XSP7@135623|Vibrionales 135623|Vibrionales N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin - - - ko:K02400 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 - - FHIPEP k141_25768_1 1191299.AJYX01000102_gene2547 0.000485 40.8 2B6TJ@1|root,31ZSV@2|Bacteria,1QKJQ@1224|Proteobacteria,1TIPY@1236|Gammaproteobacteria,1XZFT@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_22041_1 406124.ACPC01000008_gene1703 1.76e-35 125.0 COG0537@1|root,COG0537@2|Bacteria,1V83D@1239|Firmicutes,4HIH2@91061|Bacilli,1ZH9A@1386|Bacillus 91061|Bacilli FG Domain of unknown function (DUF4269) - - - - - - - - - - - - DUF4269 k141_22041_2 324057.Pjdr2_3938 6.51e-42 141.0 COG1051@1|root,COG1051@2|Bacteria,1V3T8@1239|Firmicutes,4HH2F@91061|Bacilli,26WQM@186822|Paenibacillaceae 91061|Bacilli F Belongs to the Nudix hydrolase family - - 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - - NUDIX k141_32642_1 218284.CCDN010000002_gene2582 5.45e-97 299.0 COG0515@1|root,COG3173@1|root,COG0515@2|Bacteria,COG3173@2|Bacteria,1U4B2@1239|Firmicutes,4HG90@91061|Bacilli,1ZR5R@1386|Bacillus 91061|Bacilli KLT Phosphotransferase enzyme family - - 2.7.11.1 ko:K08884 - - - - ko00000,ko01000,ko01001 - - - APH k141_20790_1 1294265.JCM21738_4929 5.74e-109 317.0 COG5012@1|root,COG5012@2|Bacteria,1UIJC@1239|Firmicutes,4ISK1@91061|Bacilli,1ZSBS@1386|Bacillus 91061|Bacilli S B12 binding domain - - - ko:K22491 - - - - ko00000,ko03000 - - - B12-binding,B12-binding_2,MerR_1 k141_27843_1 1453501.JELR01000002_gene1134 5.6e-99 295.0 COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,1RRA1@1236|Gammaproteobacteria,4641H@72275|Alteromonadaceae 1236|Gammaproteobacteria S esterase of the alpha-beta hydrolase superfamily rssA GO:0003674,GO:0003824,GO:0016787 - ko:K07001 - - - - ko00000 - - - Patatin k141_27082_1 1382305.AZUC01000046_gene331 4.56e-51 166.0 COG0406@1|root,COG0406@2|Bacteria,1V6ES@1239|Firmicutes,4HJVI@91061|Bacilli,26F33@186818|Planococcaceae 91061|Bacilli G phosphoglycerate mutase gpmA - 5.4.2.12 ko:K15634 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000 - - - His_Phos_1 k141_13941_1 1279017.AQYJ01000028_gene2164 4.77e-28 111.0 COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,1RND5@1236|Gammaproteobacteria,464ZN@72275|Alteromonadaceae 1236|Gammaproteobacteria CH COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases visC GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016491,GO:0019168,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901576,GO:1901661,GO:1901663 - ko:K03184,ko:K18800 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04987,R06146,R08768,R08775 RC00046,RC01254 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_3 k141_13941_2 1279017.AQYJ01000028_gene2163 1e-187 534.0 COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,1RMS3@1236|Gammaproteobacteria,464X1@72275|Alteromonadaceae 1236|Gammaproteobacteria CH COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases ubiH GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008681,GO:0009058,GO:0009108,GO:0009314,GO:0009416,GO:0009628,GO:0009987,GO:0016491,GO:0016705,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0050896,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901576,GO:1901661,GO:1901663 - ko:K03185,ko:K18800 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04987,R04989,R08768,R08773 RC00046,RC02670 ko00000,ko00001,ko00002,ko01000 - - iB21_1397.B21_02702,iECBD_1354.ECBD_0830,iECB_1328.ECB_02739,iECD_1391.ECD_02739,iEcHS_1320.EcHS_A3066 FAD_binding_3 k141_13941_3 1042377.AFPJ01000024_gene819 6.57e-181 514.0 COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,1RN0W@1236|Gammaproteobacteria,464SX@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0006 Xaa-Pro aminopeptidase pepP - 3.4.11.9 ko:K01262 - - - - ko00000,ko01000,ko01002 - - - AMP_N,Peptidase_M24 k141_35210_1 218284.CCDN010000001_gene989 2.69e-75 245.0 COG1884@1|root,COG1884@2|Bacteria,1TSVA@1239|Firmicutes,4HDE1@91061|Bacilli,1ZAVR@1386|Bacillus 91061|Bacilli I COG1884 Methylmalonyl-CoA mutase, N-terminal domain subunit mutA - 5.4.99.2 ko:K01847 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00373,M00376,M00741 R00833 RC00395 ko00000,ko00001,ko00002,ko01000 - - - MM_CoA_mutase k141_29137_2 1408303.JNJJ01000036_gene1596 2.81e-20 87.8 2EDJZ@1|root,337FS@2|Bacteria,1W0HQ@1239|Firmicutes,4HYUF@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - k141_11494_1 1385513.N780_14010 1.33e-27 110.0 COG5522@1|root,COG5522@2|Bacteria,1V57K@1239|Firmicutes,4HHZD@91061|Bacilli,2YA9N@289201|Pontibacillus 91061|Bacilli S ABC transporter permease - - - - - - - - - - - - Intg_mem_TP0381 k141_10338_1 1116375.VEJY3_04125 3e-310 874.0 COG4412@1|root,COG4935@1|root,COG4412@2|Bacteria,COG4935@2|Bacteria,1RKAD@1224|Proteobacteria,1S8JD@1236|Gammaproteobacteria,1XSHD@135623|Vibrionales 135623|Vibrionales Q Immune inhibitor A peptidase M6 - - - - - - - - - - - - Peptidase_M6 k141_10338_2 1116375.VEJY3_04120 8.37e-285 783.0 COG0168@1|root,COG0168@2|Bacteria,1N412@1224|Proteobacteria,1RR24@1236|Gammaproteobacteria,1XSUX@135623|Vibrionales 135623|Vibrionales P COG0168 Trk-type K transport systems, membrane components ktrB - - ko:K03498 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkH k141_10338_3 1116375.VEJY3_04115 3.92e-140 397.0 COG0569@1|root,COG0569@2|Bacteria,1N64R@1224|Proteobacteria,1SZZF@1236|Gammaproteobacteria,1XURF@135623|Vibrionales 135623|Vibrionales P TrkA-N domain ktrA - - ko:K03499 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkA_C,TrkA_N k141_10338_4 223926.28805890 6.75e-275 754.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RSQU@1236|Gammaproteobacteria,1XTY9@135623|Vibrionales 135623|Vibrionales JKL Belongs to the DEAD box helicase family rhlE-1 - - - - - - - - - - - DEAD,Helicase_C k141_10338_5 1116375.VEJY3_04105 5.96e-262 724.0 COG1253@1|root,COG1253@2|Bacteria,1MV3P@1224|Proteobacteria,1T1MS@1236|Gammaproteobacteria,1XT0K@135623|Vibrionales 135623|Vibrionales P COG1253 Hemolysins and related proteins containing CBS domains - - - ko:K03699 - - - - ko00000,ko02042 - - - CBS,CorC_HlyC,DUF21 k141_10338_6 1116375.VEJY3_04100 0.0 1196.0 COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,1RNHR@1236|Gammaproteobacteria,1XV3F@135623|Vibrionales 135623|Vibrionales P Iron-regulated outer membrane virulence protein cirA GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - ko:K16089 - - - - ko00000,ko02000 1.B.14.1,1.B.14.10 - - Plug,TonB_dep_Rec k141_10338_7 1116375.VEJY3_04095 2.27e-122 354.0 COG2977@1|root,COG2977@2|Bacteria,1MZK2@1224|Proteobacteria,1S968@1236|Gammaproteobacteria,1XYU9@135623|Vibrionales 135623|Vibrionales Q Belongs to the P-Pant transferase superfamily - - 6.3.2.14 ko:K02362 ko01053,ko01110,ko01130,map01053,map01110,map01130 - R07644 RC00162,RC03046 ko00000,ko00001,ko01000 - - - ACPS k141_10338_8 1116375.VEJY3_04090 3.35e-160 456.0 2AMVA@1|root,316R7@2|Bacteria,1PXX6@1224|Proteobacteria,1THDA@1236|Gammaproteobacteria,1Y0B7@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_10338_9 1116375.VEJY3_04085 0.0 1046.0 COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,1RPAG@1236|Gammaproteobacteria,1XSKY@135623|Vibrionales 135623|Vibrionales Q COG1020 Non-ribosomal peptide synthetase modules and related proteins - - 6.3.2.14 ko:K02364 ko01053,ko01110,ko01130,map01053,map01110,map01130 - R07644 RC00162,RC03046 ko00000,ko00001,ko01000,ko01008 - - - AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase k141_12753_1 1042377.AFPJ01000038_gene1121 2.44e-190 551.0 COG4206@1|root,COG4206@2|Bacteria,1MUZG@1224|Proteobacteria,1RP7I@1236|Gammaproteobacteria,463Z2@72275|Alteromonadaceae 1236|Gammaproteobacteria H COG1629 Outer membrane receptor proteins, mostly Fe transport - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - CarboxypepD_reg,Plug,TonB_dep_Rec k141_801_1 1279017.AQYJ01000029_gene3320 7.9e-115 337.0 COG1076@1|root,COG1076@2|Bacteria,1N270@1224|Proteobacteria,1RP0P@1236|Gammaproteobacteria,4673B@72275|Alteromonadaceae 1236|Gammaproteobacteria O Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host djlA - - ko:K05801 - - - - ko00000,ko03110 - - - DnaJ,TerB k141_5556_1 218284.CCDN010000001_gene200 7.44e-215 605.0 COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,4H9VD@91061|Bacilli,1ZAU2@1386|Bacillus 91061|Bacilli G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) ptsI GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0051179,GO:0051234,GO:0071702 2.7.3.9 ko:K08483 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 8.A.7 - - PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C k141_20791_1 1188252.AJYK01000062_gene1925 2.13e-34 130.0 COG2207@1|root,COG2207@2|Bacteria,1MX23@1224|Proteobacteria,1RRXM@1236|Gammaproteobacteria,1Y2JT@135623|Vibrionales 135623|Vibrionales K Arabinose-binding domain of AraC transcription regulator, N-term - - - - - - - - - - - - Arabinose_bd,HTH_18 k141_13942_1 218284.CCDN010000001_gene1825 1.18e-109 323.0 COG2855@1|root,COG2855@2|Bacteria,1TQYA@1239|Firmicutes,4HCCP@91061|Bacilli,1ZATM@1386|Bacillus 91061|Bacilli S Conserved hypothetical protein 698 - - - - - - - - - - - - Cons_hypoth698 k141_23379_1 1307436.PBF_17434 2.25e-66 209.0 COG2159@1|root,COG2159@2|Bacteria,1TSSX@1239|Firmicutes,4HE0Z@91061|Bacilli,1ZEV5@1386|Bacillus 91061|Bacilli S Amidohydrolase - - - ko:K07045 - - - - ko00000 - - - Amidohydro_2 k141_37424_1 1517681.HW45_10560 3.77e-65 213.0 COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,1RMJ1@1236|Gammaproteobacteria,1XTXF@135623|Vibrionales 135623|Vibrionales L Belongs to the 'phage' integrase family - - - - - - - - - - - - Arm-DNA-bind_3,Phage_int_SAM_3,Phage_integrase k141_24475_1 1121374.KB891576_gene518 1.89e-197 562.0 COG0531@1|root,COG0531@2|Bacteria,1MUP1@1224|Proteobacteria,1RR0V@1236|Gammaproteobacteria 1236|Gammaproteobacteria E amino acid - - - ko:K20265 ko02024,map02024 - - - ko00000,ko00001,ko02000 2.A.3.7.1,2.A.3.7.3 - - AA_permease_2 k141_24475_2 1042377.AFPJ01000012_gene1374 2.01e-293 806.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,465UR@72275|Alteromonadaceae 1236|Gammaproteobacteria C Belongs to the aldehyde dehydrogenase family - - 1.2.1.3 ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_24475_3 1042377.AFPJ01000012_gene1373 7.41e-166 471.0 COG0583@1|root,COG0583@2|Bacteria,1REJ5@1224|Proteobacteria,1S432@1236|Gammaproteobacteria,46CVM@72275|Alteromonadaceae 1236|Gammaproteobacteria K Bacterial regulatory helix-turn-helix protein, lysR family - - - ko:K03566 ko02026,map02026 - - - ko00000,ko00001,ko03000 - - - HTH_1,LysR_substrate k141_24475_4 1042377.AFPJ01000012_gene1372 2.38e-261 720.0 COG0624@1|root,COG0624@2|Bacteria,1MVUX@1224|Proteobacteria,1RPPD@1236|Gammaproteobacteria,4656D@72275|Alteromonadaceae 1236|Gammaproteobacteria E allantoate amidohydrolase - - 3.5.1.6,3.5.1.87 ko:K06016 ko00240,ko01100,map00240,map01100 M00046 R00905,R04666 RC00096 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20,Peptidase_M28 k141_7731_1 1307436.PBF_05678 2.48e-60 191.0 COG4297@1|root,COG4297@2|Bacteria,1V6MJ@1239|Firmicutes,4HJGB@91061|Bacilli,1ZGYD@1386|Bacillus 91061|Bacilli S Cupin domain yjlB - - - - - - - - - - - Cupin_1,Cupin_2 k141_10353_1 1294265.JCM21738_461 2.83e-16 81.3 COG0243@1|root,COG0243@2|Bacteria,1UYJX@1239|Firmicutes,4HE4J@91061|Bacilli 91061|Bacilli C belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - - - - - - - - - - Molybdopterin,Molydop_binding k141_10353_2 1294265.JCM21738_462 2.08e-23 93.2 2C35K@1|root,342VZ@2|Bacteria,1VY0K@1239|Firmicutes,4HX77@91061|Bacilli,1ZNC1@1386|Bacillus 91061|Bacilli S Nitrate reductase delta subunit - - - - - - - - - - - - Nitrate_red_del k141_23417_1 1453501.JELR01000001_gene1913 6.3e-85 258.0 2CH0A@1|root,2ZANK@2|Bacteria,1R6U4@1224|Proteobacteria,1RQ3J@1236|Gammaproteobacteria,466JM@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_23417_2 1042377.AFPJ01000037_gene2926 1.29e-130 380.0 COG0613@1|root,COG0613@2|Bacteria,1MWIH@1224|Proteobacteria,1RNCG@1236|Gammaproteobacteria,466MQ@72275|Alteromonadaceae 1236|Gammaproteobacteria S metal-dependent phosphoesterases (PHP family) trpH GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004532,GO:0004534,GO:0004536,GO:0004540,GO:0005488,GO:0006139,GO:0006259,GO:0006521,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008252,GO:0008409,GO:0009987,GO:0010565,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016796,GO:0016895,GO:0016896,GO:0019222,GO:0030145,GO:0031323,GO:0033238,GO:0034641,GO:0035312,GO:0042578,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090305,GO:0090357,GO:0090501,GO:0090503,GO:0140097,GO:0140098,GO:1901360 3.1.3.97 ko:K07053 - - R00188,R11188 RC00078 ko00000,ko01000 - - - PHP k141_5586_1 218284.CCDN010000001_gene1178 2.8e-51 163.0 2E93T@1|root,333CR@2|Bacteria,1VFQW@1239|Firmicutes,4HPTY@91061|Bacilli,1ZISY@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_5586_2 218284.CCDN010000001_gene1179 1.47e-61 191.0 COG0328@1|root,COG0328@2|Bacteria,1VH2B@1239|Firmicutes,4HIY9@91061|Bacilli,1ZH35@1386|Bacillus 91061|Bacilli L An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids rnhA - 3.1.26.4 ko:K03469 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_H,RVT_3 k141_35247_1 1042377.AFPJ01000028_gene2261 4.75e-56 178.0 COG5589@1|root,COG5589@2|Bacteria,1NGHI@1224|Proteobacteria,1SGFT@1236|Gammaproteobacteria,468Z5@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF2390) - - - - - - - - - - - - DUF2390 k141_18665_1 218284.CCDN010000002_gene2219 1.34e-54 183.0 COG1017@1|root,COG1018@1|root,COG1017@2|Bacteria,COG1018@2|Bacteria,1TRG2@1239|Firmicutes,4HAU3@91061|Bacilli,1ZAP9@1386|Bacillus 91061|Bacilli C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress hmp GO:0000166,GO:0001505,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008941,GO:0009056,GO:0009987,GO:0016491,GO:0016705,GO:0016708,GO:0017144,GO:0033554,GO:0034641,GO:0036094,GO:0042133,GO:0042135,GO:0042737,GO:0043167,GO:0043168,GO:0044237,GO:0044248,GO:0044270,GO:0044464,GO:0046209,GO:0046210,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051213,GO:0051409,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0071500,GO:0071949,GO:0072593,GO:0097159,GO:1901265,GO:1901363,GO:2001057 1.14.12.17,1.18.1.3 ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 M00538 R02550,R03562,R05666,R09513 RC00269,RC00490,RC02556 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_6,Globin,NAD_binding_1 k141_18665_2 796606.BMMGA3_03230 3.55e-17 73.9 29RXQ@1|root,30D20@2|Bacteria,1UAQ9@1239|Firmicutes,4IM2Y@91061|Bacilli,1ZIYI@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_7732_1 935837.JAEK01000010_gene94 5.27e-132 396.0 COG0243@1|root,COG0243@2|Bacteria,1VTS0@1239|Firmicutes,4HAZ4@91061|Bacilli,1ZBMY@1386|Bacillus 91061|Bacilli C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family fdhA - - - - - - - - - - - Molybdopterin,Molydop_binding k141_2980_1 1273538.G159_01590 1.4e-22 98.2 COG1680@1|root,COG1680@2|Bacteria,1U828@1239|Firmicutes,4HA0Q@91061|Bacilli,26E14@186818|Planococcaceae 91061|Bacilli V Beta-lactamase class C estB - - - - - - - - - - - Beta-lactamase,Peptidase_M6 k141_2980_2 1273538.G159_01595 5.09e-24 102.0 COG1472@1|root,COG1472@2|Bacteria,1TP63@1239|Firmicutes,4HBDB@91061|Bacilli,26D9M@186818|Planococcaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 3 family ybbD - 3.2.1.52 ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 M00628 R00022,R05963,R07809,R07810,R10831 RC00049 ko00000,ko00001,ko00002,ko01000 - - - Big_2,Glyco_hydro_3,Glyco_hydro_3_C,Gram_pos_anchor,SLH k141_30238_1 218284.CCDN010000007_gene3946 1.3e-45 163.0 COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H9SA@91061|Bacilli,1ZBUK@1386|Bacillus 91061|Bacilli M penicillin-binding protein pbpG GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.4.1.129,3.4.16.4 ko:K21464 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase k141_13981_1 218284.CCDN010000008_gene4185 1.52e-262 737.0 COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,4HAG1@91061|Bacilli,1ZARG@1386|Bacillus 91061|Bacilli J Belongs to the class-I aminoacyl-tRNA synthetase family leuS GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Anticodon_1,tRNA-synt_1,tRNA-synt_1_2 k141_35248_1 935557.ATYB01000009_gene1178 1.22e-40 141.0 COG5588@1|root,COG5588@2|Bacteria,1RGIE@1224|Proteobacteria,2U11D@28211|Alphaproteobacteria,4BNPP@82115|Rhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF1326) - - - - - - - - - - - - DUF1326 k141_11523_1 617140.AJZE01000049_gene324 1.23e-157 450.0 COG1802@1|root,COG1802@2|Bacteria,1R40P@1224|Proteobacteria,1RSE4@1236|Gammaproteobacteria,1XTAG@135623|Vibrionales 135623|Vibrionales K COG1802 Transcriptional regulators - - - - - - - - - - - - FCD,GntR k141_11523_2 1116375.VEJY3_07820 2.85e-70 231.0 COG1629@1|root,COG4771@2|Bacteria,1MUPZ@1224|Proteobacteria,1RMMP@1236|Gammaproteobacteria,1XSP3@135623|Vibrionales 135623|Vibrionales M COG1629 Outer membrane receptor proteins, mostly Fe transport iutA - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_27123_1 1231057.AMGD01000002_gene2374 2.48e-08 53.9 COG5496@1|root,COG5496@2|Bacteria,1UH3T@1239|Firmicutes,4HJC5@91061|Bacilli,26HCT@186818|Planococcaceae 91061|Bacilli S Thioesterase - - - - - - - - - - - - 4HBT k141_19750_1 1279017.AQYJ01000023_gene3247 5.1e-71 240.0 COG4223@1|root,COG4223@2|Bacteria,1N10X@1224|Proteobacteria,1RYCQ@1236|Gammaproteobacteria,46D2D@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF1631) - - - - - - - - - - - - DUF1631 k141_6686_2 1232683.ADIMK_2440 0.0 884.0 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1RMQ4@1236|Gammaproteobacteria,465RZ@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II acs - - ko:K00666 - - - - ko00000,ko01000,ko01004 - - - AMP-binding,AMP-binding_C k141_5587_1 1042377.AFPJ01000005_gene2453 7.9e-99 289.0 2DM5Y@1|root,31UPK@2|Bacteria,1NUSA@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_5587_2 1453501.JELR01000002_gene1161 1.16e-45 151.0 COG0625@1|root,COG0625@2|Bacteria,1MY47@1224|Proteobacteria,1RRI3@1236|Gammaproteobacteria,467CI@72275|Alteromonadaceae 1236|Gammaproteobacteria O Glutathione S-transferase, C-terminal domain - - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C,GST_C_2,GST_C_3,GST_N,GST_N_2,GST_N_3 k141_29157_1 1453501.JELR01000002_gene372 1.49e-111 325.0 COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,1RM8I@1236|Gammaproteobacteria,466HI@72275|Alteromonadaceae 1236|Gammaproteobacteria G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) tpiA GO:0003674,GO:0003824,GO:0004807,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01015 RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 - - iJN746.PP_4715 TIM k141_2981_1 42565.FP66_11090 6.94e-19 84.7 COG0548@1|root,COG1246@1|root,COG0548@2|Bacteria,COG1246@2|Bacteria,1MUUP@1224|Proteobacteria,1RMV5@1236|Gammaproteobacteria,1XH3F@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the acetyltransferase family. ArgA subfamily argA - 2.3.1.1 ko:K14682 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R00259 RC00004,RC00064 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,Acetyltransf_1 k141_20810_1 218284.CCDN010000001_gene132 1.76e-106 336.0 COG1038@1|root,COG1038@2|Bacteria,1UHP9@1239|Firmicutes,4IS56@91061|Bacilli,1ZC4R@1386|Bacillus 91061|Bacilli C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second pyc - 6.4.1.1 ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 M00173 R00344 RC00040,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,HMGL-like,PYC_OADA k141_17284_1 218284.CCDN010000005_gene3342 3.07e-137 392.0 COG1295@1|root,COG1295@2|Bacteria,1U7HM@1239|Firmicutes,4H9MJ@91061|Bacilli,1ZCX5@1386|Bacillus 91061|Bacilli S Virulence factor BrkB yihY - - ko:K07058 - - - - ko00000 - - - Virul_fac_BrkB k141_17284_2 1382358.JHVN01000013_gene1812 1.27e-38 137.0 COG3483@1|root,COG3483@2|Bacteria,1TR14@1239|Firmicutes,4H9X1@91061|Bacilli 91061|Bacilli E Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety kynA GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019752,GO:0020037,GO:0022607,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.11 ko:K00453 ko00380,ko01100,map00380,map01100 M00038 R00678 RC00356 ko00000,ko00001,ko00002,ko01000 - - - Trp_dioxygenase k141_27124_1 1348635.BBJY01000003_gene3909 7.29e-28 110.0 COG1929@1|root,COG1929@2|Bacteria,1MVG9@1224|Proteobacteria,1RMC6@1236|Gammaproteobacteria,1XSHV@135623|Vibrionales 135623|Vibrionales G Belongs to the glycerate kinase type-1 family glxK - 2.7.1.165 ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 - R08572 RC00002,RC00428 ko00000,ko00001,ko01000 - - - Gly_kinase k141_13982_1 391165.GbCGDNIH1_2378 3.8e-73 244.0 COG4264@1|root,COG4264@2|Bacteria,1QUJJ@1224|Proteobacteria,2U1A2@28211|Alphaproteobacteria,2JWF5@204441|Rhodospirillales 204441|Rhodospirillales Q IucA / IucC family - - 6.3.2.38 ko:K03894 ko00310,ko01120,map00310,map01120 - R10090 RC00064,RC00090 ko00000,ko00001,ko01000 - - - FhuF,IucA_IucC k141_37442_1 218284.CCDN010000006_gene3666 2.25e-65 210.0 COG0265@1|root,COG0265@2|Bacteria,1TSBA@1239|Firmicutes,4HA05@91061|Bacilli,1ZAQG@1386|Bacillus 91061|Bacilli O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain minJ - - - - - - - - - - - PDZ_2 k141_37442_2 1526927.Plano_2935 1.37e-60 198.0 COG1301@1|root,COG1301@2|Bacteria,1TPME@1239|Firmicutes,4HB4X@91061|Bacilli,26EIK@186818|Planococcaceae 91061|Bacilli U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - - - - - - - - - - SDF k141_24477_1 1196031.ALEG01000019_gene2888 6.53e-15 73.6 COG0287@1|root,COG0287@2|Bacteria,1TPXG@1239|Firmicutes,4HBI4@91061|Bacilli,1ZBVZ@1386|Bacillus 91061|Bacilli E prephenate dehydrogenase tyrA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.3.1.12 ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00025 R01728 RC00125 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU22610 ACT,PDH k141_24477_2 218284.CCDN010000001_gene1119 5.38e-266 733.0 COG0128@1|root,COG0128@2|Bacteria,1TPIH@1239|Firmicutes,4HBHZ@91061|Bacilli,1ZBP0@1386|Bacillus 91061|Bacilli E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate aroA GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03460 RC00350 ko00000,ko00001,ko00002,ko01000 - - - EPSP_synthase k141_34011_1 1453501.JELR01000005_gene1665 2.39e-114 366.0 COG2982@1|root,COG2982@2|Bacteria,1MUME@1224|Proteobacteria,1RNPC@1236|Gammaproteobacteria,464KK@72275|Alteromonadaceae 1236|Gammaproteobacteria M Domain of Unknown Function (DUF748) - - - - - - - - - - - - DUF748,OmpA k141_23419_1 218284.CCDN010000001_gene1027 1.71e-162 462.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,1ZB7V@1386|Bacillus 91061|Bacilli I Belongs to the thiolase family atoB GO:0003674,GO:0003824,GO:0003988,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - iYO844.BSU24170 Thiolase_C,Thiolase_N k141_27869_2 1123226.KB899284_gene3745 0.000288 45.1 COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,4H9RZ@91061|Bacilli,26SUA@186822|Paenibacillaceae 91061|Bacilli NT Single cache domain 3 tlpC - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal,sCache_3_3 k141_25801_1 1288826.MSNKSG1_14092 2.07e-177 498.0 COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,1RPNX@1236|Gammaproteobacteria,464T8@72275|Alteromonadaceae 1236|Gammaproteobacteria K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_25801_2 1288826.MSNKSG1_14087 1.05e-81 245.0 COG2259@1|root,COG2259@2|Bacteria,1RDYW@1224|Proteobacteria,1S3RT@1236|Gammaproteobacteria,466ZI@72275|Alteromonadaceae 1236|Gammaproteobacteria S TQO small subunit DoxD - - - ko:K15977 - - - - ko00000 - - - DoxX k141_5715_2 1116375.VEJY3_19916 3.04e-261 719.0 COG3007@1|root,COG3007@2|Bacteria,1QJA8@1224|Proteobacteria,1RU33@1236|Gammaproteobacteria,1XTE7@135623|Vibrionales 135623|Vibrionales I Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP) fabV2 - 1.3.1.44,1.3.1.9 ko:K00209 ko00061,ko00650,ko01100,ko01120,ko01200,ko01212,map00061,map00650,map01100,map01120,map01200,map01212 M00083 R01171,R04429,R04724,R04955,R04958,R04961,R04966,R04969 RC00052,RC00076 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Eno-Rase_FAD_bd,Eno-Rase_NADH_b,Enoyl_reductase k141_5715_3 1116375.VEJY3_19911 4.65e-113 326.0 COG2755@1|root,COG2755@2|Bacteria,1RCXZ@1224|Proteobacteria,1S3QU@1236|Gammaproteobacteria,1XVT0@135623|Vibrionales 135623|Vibrionales E COG2755 Lysophospholipase L1 and related esterases tesA - 3.1.1.5 ko:K10804 ko01040,map01040 - - - ko00000,ko00001,ko01000,ko01004 - - - Lipase_GDSL_2 k141_5715_4 1116375.VEJY3_19906 2.45e-148 419.0 COG4181@1|root,COG4181@2|Bacteria,1MXG9@1224|Proteobacteria,1RMG1@1236|Gammaproteobacteria,1XU0B@135623|Vibrionales 135623|Vibrionales Q ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component ybbA - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_5715_5 1219076.N646_4270 0.0 1334.0 COG3127@1|root,COG3127@2|Bacteria,1MU9R@1224|Proteobacteria,1RM8Y@1236|Gammaproteobacteria,1XSX0@135623|Vibrionales 135623|Vibrionales Q ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX k141_5715_6 1116375.VEJY3_19896 2.53e-304 834.0 COG0654@1|root,COG0654@2|Bacteria,1NPQT@1224|Proteobacteria,1T1YT@1236|Gammaproteobacteria,1XTXS@135623|Vibrionales 135623|Vibrionales CH FAD dependent oxidoreductase - - - - - - - - - - - - DAO k141_5715_7 1116375.VEJY3_19891 2.76e-199 555.0 COG1984@1|root,COG1984@2|Bacteria,1MU9H@1224|Proteobacteria,1RR39@1236|Gammaproteobacteria,1XTJ1@135623|Vibrionales 135623|Vibrionales E Allophanate hydrolase subunit 2 - - - - - - - - - - - - CT_A_B k141_5715_8 1116375.VEJY3_19886 3.32e-117 340.0 COG2049@1|root,COG2049@2|Bacteria,1MWRB@1224|Proteobacteria,1RQIQ@1236|Gammaproteobacteria,1XX9Y@135623|Vibrionales 135623|Vibrionales E Allophanate hydrolase, subunit 1 - - - - - - - - - - - - CT_C_D k141_5715_9 1116375.VEJY3_19881 7.22e-171 478.0 COG1540@1|root,COG1540@2|Bacteria,1MUYV@1224|Proteobacteria,1RSCZ@1236|Gammaproteobacteria,1XV4U@135623|Vibrionales 135623|Vibrionales S Belongs to the UPF0271 (lamB) family - - - ko:K07160 - - - - ko00000 - - - LamB_YcsF k141_5715_10 223926.28809179 1.25e-90 292.0 COG2199@1|root,COG2199@2|Bacteria,1RGCV@1224|Proteobacteria,1T259@1236|Gammaproteobacteria,1XU5C@135623|Vibrionales 135623|Vibrionales T Periplasmic sensor domain - - - - - - - - - - - - CHASE8,GGDEF,HAMP,PAS,PAS_8,PAS_9 k141_16279_1 218284.CCDN010000001_gene1486 6.63e-51 164.0 28NEG@1|root,32W71@2|Bacteria,1VAPN@1239|Firmicutes,4HQ5K@91061|Bacilli,1ZRE2@1386|Bacillus 91061|Bacilli S Staygreen protein - - - - - - - - - - - - Staygreen k141_25974_1 218284.CCDN010000001_gene69 1.04e-132 382.0 COG2302@1|root,COG2302@2|Bacteria,1U5V2@1239|Firmicutes,4HD3F@91061|Bacilli,1ZC97@1386|Bacillus 91061|Bacilli S conserved protein, contains S4-like domain ylmH - - - - - - - - - - - S4 k141_25974_2 218284.CCDN010000001_gene68 2.53e-82 246.0 COG3599@1|root,COG3599@2|Bacteria,1V27M@1239|Firmicutes,4HG80@91061|Bacilli,1ZFNB@1386|Bacillus 91061|Bacilli D Cell division initiation protein divIVA GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K04074 - - - - ko00000,ko03036 - - - DivIVA k141_10437_1 665952.HMPREF1015_00522 3.72e-123 387.0 COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,4H9T3@91061|Bacilli,1ZCIC@1386|Bacillus 91061|Bacilli L DNA polymerase dnaE - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon k141_18954_1 218284.CCDN010000002_gene2343 7.53e-52 173.0 COG1595@1|root,COG1595@2|Bacteria,1VEMV@1239|Firmicutes,4HP80@91061|Bacilli,1ZFIF@1386|Bacillus 91061|Bacilli K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_24648_1 1279017.AQYJ01000026_gene46 3.63e-99 309.0 COG0784@1|root,COG1982@1|root,COG0784@2|Bacteria,COG1982@2|Bacteria,1MWK4@1224|Proteobacteria,1RMVF@1236|Gammaproteobacteria,464W7@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG1982 Arginine lysine ornithine decarboxylases adiA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0006873,GO:0006885,GO:0008144,GO:0008150,GO:0008152,GO:0008792,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016829,GO:0016830,GO:0016831,GO:0019725,GO:0019752,GO:0019842,GO:0030003,GO:0030004,GO:0030170,GO:0030641,GO:0036094,GO:0042592,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0045852,GO:0046395,GO:0048037,GO:0048878,GO:0050662,GO:0050801,GO:0051453,GO:0051454,GO:0055067,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0070279,GO:0071704,GO:0097159,GO:0098771,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 4.1.1.19 ko:K01584 ko00330,ko01100,map00330,map01100 M00133 R00566 RC00299 ko00000,ko00001,ko00002,ko01000 - - iEC042_1314.EC042_4483 OKR_DC_1,OKR_DC_1_C,OKR_DC_1_N k141_7935_1 1294265.JCM21738_2156 3.46e-88 265.0 2BZ6P@1|root,2Z8AB@2|Bacteria,1TRT3@1239|Firmicutes,4HDZH@91061|Bacilli,1ZCVP@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF2935) M1-671 - - - - - - - - - - - DUF2935 k141_17397_1 218284.CCDN010000001_gene756 3.78e-108 323.0 COG0423@1|root,COG0423@2|Bacteria,1TP94@1239|Firmicutes,4HB9A@91061|Bacilli,1ZCAP@1386|Bacillus 91061|Bacilli J Catalyzes the attachment of glycine to tRNA(Gly) glyQS GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.14 ko:K01880 ko00970,map00970 M00359,M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - iSB619.SA_RS07880 HGTP_anticodon,tRNA-synt_2b k141_35429_1 1034347.CAHJ01000064_gene947 1.35e-92 279.0 COG1494@1|root,COG1494@2|Bacteria,1TP0D@1239|Firmicutes,4H9MV@91061|Bacilli,1ZD19@1386|Bacillus 91061|Bacilli G fructose-1,6-bisphosphatase glpX - 3.1.3.11 ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 M00003,M00165,M00167 R00762,R04780 RC00017 ko00000,ko00001,ko00002,ko01000 - - - FBPase_glpX k141_35429_2 1294265.JCM21738_5510 3.29e-55 172.0 2CGTU@1|root,32Z9H@2|Bacteria,1VG36@1239|Firmicutes,4HNI4@91061|Bacilli,1ZI34@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3055) - - - - - - - - - - - - DUF3055 k141_6917_1 1385511.N783_03860 2.18e-05 44.3 COG3847@1|root,COG3847@2|Bacteria 2|Bacteria U Flp Fap pilin component pilA - - ko:K02651 ko04112,map04112 - - - ko00000,ko00001,ko02035,ko02044 - - - Class_IIIsignal,Flp_Fap k141_12891_2 796606.BMMGA3_05540 1.66e-66 206.0 COG0742@1|root,COG0742@2|Bacteria,1V3JF@1239|Firmicutes,4HGXT@91061|Bacilli,1ZFNI@1386|Bacillus 91061|Bacilli L Methyltransferase rsmD - 2.1.1.171 ko:K08316 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - Cons_hypoth95 k141_16280_1 1279017.AQYJ01000024_gene946 1.16e-49 171.0 COG3486@1|root,COG3486@2|Bacteria,1MX36@1224|Proteobacteria,1RZXS@1236|Gammaproteobacteria,46A75@72275|Alteromonadaceae 1236|Gammaproteobacteria Q L-lysine 6-monooxygenase (NADPH-requiring) - - 1.14.13.195,1.14.13.196,1.14.13.59 ko:K03897,ko:K10531 ko00310,ko01120,map00310,map01120 - R00448 RC00298 ko00000,ko00001,ko01000 - - - K_oxygenase k141_11698_2 218284.CCDN010000002_gene2108 2.58e-195 551.0 COG0508@1|root,COG0508@2|Bacteria,1U936@1239|Firmicutes,4HAUD@91061|Bacilli,1ZDJK@1386|Bacillus 91061|Bacilli C 2-oxoacid dehydrogenases acyltransferase (catalytic domain) pdhC2 - 2.3.1.12 ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding k141_983_1 1279017.AQYJ01000026_gene31 1.43e-268 772.0 COG4913@1|root,COG4913@2|Bacteria,1N16Z@1224|Proteobacteria,1RYVF@1236|Gammaproteobacteria,465ZJ@72275|Alteromonadaceae 1236|Gammaproteobacteria S Putative exonuclease SbcCD, C subunit - - - - - - - - - - - - AAA_29,SbcCD_C k141_19929_2 1385513.N780_08855 8.18e-57 181.0 COG1846@1|root,COG1846@2|Bacteria,1VD1F@1239|Firmicutes,4HJ28@91061|Bacilli,2YBIJ@289201|Pontibacillus 91061|Bacilli K MarR family transcriptional regulator - - - - - - - - - - - - MarR k141_24691_1 1453501.JELR01000001_gene2916 1.77e-128 373.0 COG0665@1|root,COG0665@2|Bacteria,1N1TN@1224|Proteobacteria,1RPIZ@1236|Gammaproteobacteria,466AB@72275|Alteromonadaceae 1236|Gammaproteobacteria E FAD dependent oxidoreductase thiO - 1.4.3.19 ko:K03153 ko00730,ko01100,map00730,map01100 - R07463 RC01788 ko00000,ko00001,ko01000 - - - DAO k141_29359_1 1279017.AQYJ01000026_gene140 2.93e-160 462.0 COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,1RSGI@1236|Gammaproteobacteria,469QZ@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Flavin containing amine oxidoreductase - - - - - - - - - - - - Amino_oxidase,DAO k141_25999_1 1453501.JELR01000002_gene983 8.36e-90 283.0 COG0699@1|root,COG0699@2|Bacteria,1MXBK@1224|Proteobacteria,1RSJC@1236|Gammaproteobacteria,465QM@72275|Alteromonadaceae 1236|Gammaproteobacteria S GTPases (dynamin-related) - - - - - - - - - - - - Dynamin_N k141_29360_2 1294265.JCM21738_452 1.03e-47 164.0 COG2204@1|root,COG2204@2|Bacteria,1VSKG@1239|Firmicutes,4HCST@91061|Bacilli,1ZCPN@1386|Bacillus 91061|Bacilli T Sigma-54 interaction domain - - - ko:K02481 - - - - ko00000,ko02022 - - - HTH_8,Response_reg,Sigma54_activat k141_24692_1 665952.HMPREF1015_02217 2.22e-43 153.0 COG0677@1|root,COG0677@2|Bacteria,1TPXY@1239|Firmicutes,4HAFY@91061|Bacilli,1ZC93@1386|Bacillus 91061|Bacilli M Belongs to the UDP-glucose GDP-mannose dehydrogenase family - - 1.1.1.336 ko:K02472 ko00520,ko05111,map00520,map05111 - R03317 RC00291 ko00000,ko00001,ko01000 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N k141_35457_1 1453501.JELR01000001_gene2646 1.73e-144 414.0 COG0451@1|root,COG0451@2|Bacteria,1N8PG@1224|Proteobacteria,1RWCX@1236|Gammaproteobacteria,469BZ@72275|Alteromonadaceae 1236|Gammaproteobacteria GM NAD-dependent epimerase dehydratase - - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase k141_9375_1 1122164.JHWF01000018_gene627 5.81e-21 89.4 COG1926@1|root,COG1926@2|Bacteria,1RAG8@1224|Proteobacteria,1S3SH@1236|Gammaproteobacteria,1JD8H@118969|Legionellales 118969|Legionellales F Phosphoribosyl transferase domain - - - ko:K07100 - - - - ko00000 - - - Pribosyltran k141_9375_2 292415.Tbd_1466 1.78e-16 79.3 COG2187@1|root,COG2187@2|Bacteria,1R98V@1224|Proteobacteria,2VM22@28216|Betaproteobacteria,1KSS9@119069|Hydrogenophilales 119069|Hydrogenophilales S AAA domain - - - - - - - - - - - - - k141_34194_1 218284.CCDN010000005_gene3167 3.03e-57 200.0 COG4717@1|root,COG4717@2|Bacteria,1TQP3@1239|Firmicutes,4HBCA@91061|Bacilli,1ZDHB@1386|Bacillus 91061|Bacilli L AAA domain yhaN - - - - - - - - - - - AAA_27 k141_16306_1 1294265.JCM21738_122 1.79e-24 95.1 COG0287@1|root,COG0287@2|Bacteria,1TPXG@1239|Firmicutes,4HBI4@91061|Bacilli,1ZBVZ@1386|Bacillus 91061|Bacilli E prephenate dehydrogenase tyrA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.3.1.12 ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00025 R01728 RC00125 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU22610 ACT,PDH k141_16306_2 1294265.JCM21738_121 2.5e-76 234.0 COG0079@1|root,COG0079@2|Bacteria,1TPUV@1239|Firmicutes,4HA1H@91061|Bacilli,1ZBYJ@1386|Bacillus 91061|Bacilli E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily hisC - 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k141_6969_1 218284.CCDN010000002_gene2161 9.05e-159 453.0 COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4H9KU@91061|Bacilli,1ZBF2@1386|Bacillus 91061|Bacilli G Belongs to the glycosyl hydrolase 1 family bglA7 - 3.2.1.21 ko:K05350 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 - R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - - - Glyco_hydro_1 k141_15075_1 1294265.JCM21738_84 2.49e-275 755.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,4HAEI@91061|Bacilli,1ZAX4@1386|Bacillus 91061|Bacilli E Belongs to the Glu Leu Phe Val dehydrogenases family gudB GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0055114,GO:0071704,GO:1901564 1.4.1.2 ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 - R00243 RC00006,RC02799 ko00000,ko00001,ko01000 - - - ELFV_dehydrog,ELFV_dehydrog_N k141_9376_2 583355.Caka_2468 6.47e-42 142.0 COG2947@1|root,COG2947@2|Bacteria,46VWG@74201|Verrucomicrobia,3K8C4@414999|Opitutae 414999|Opitutae S EVE domain - - - - - - - - - - - - EVE k141_14267_1 1116375.VEJY3_00725 4.15e-165 472.0 COG2233@1|root,COG2233@2|Bacteria,1MUN9@1224|Proteobacteria,1RMGW@1236|Gammaproteobacteria,1XUCK@135623|Vibrionales 135623|Vibrionales F COG2233 Xanthine uracil permeases xanP - - ko:K16345 - - - - ko00000,ko02000 2.A.40.4.2 - - Xan_ur_permease k141_14267_2 1219076.N646_2345 2.41e-40 144.0 COG0642@1|root,COG2205@2|Bacteria,1MUAK@1224|Proteobacteria,1RPP2@1236|Gammaproteobacteria,1XSMP@135623|Vibrionales 135623|Vibrionales T Osmolarity sensor protein envZ - 2.7.13.3 ko:K07638 ko02020,ko02026,map02020,map02026 M00445,M00742,M00743 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA k141_32893_2 1116375.VEJY3_22246 1.27e-54 171.0 293DP@1|root,2ZQW4@2|Bacteria,1P6Y1@1224|Proteobacteria,1STVE@1236|Gammaproteobacteria,1XZ53@135623|Vibrionales 135623|Vibrionales - - VPA0463 - - - - - - - - - - - - k141_32893_3 1116375.VEJY3_22261 2.19e-305 835.0 COG0366@1|root,COG0366@2|Bacteria,1MVQA@1224|Proteobacteria,1RPA4@1236|Gammaproteobacteria,1XSNN@135623|Vibrionales 135623|Vibrionales G alpha-amylase - - 3.2.1.1 ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 - R02108,R02112,R11262 - ko00000,ko00001,ko01000 - GH13 - Alpha-amylase k141_32893_4 1116375.VEJY3_22266 3.9e-250 689.0 COG1979@1|root,COG1979@2|Bacteria,1QUBJ@1224|Proteobacteria,1RP7C@1236|Gammaproteobacteria,1XT9D@135623|Vibrionales 135623|Vibrionales C oxidoreductases, Fe-dependent alcohol dehydrogenase family - - - ko:K08325 ko00640,map00640 - R02528 RC00739 ko00000,ko00001,ko01000 - - - Fe-ADH k141_32893_5 1116375.VEJY3_22271 2.07e-244 674.0 COG0665@1|root,COG0665@2|Bacteria,1MU7M@1224|Proteobacteria,1RS24@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Belongs to the MSOX MTOX family. MTOX subfamily solA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016647,GO:0033554,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050131,GO:0050660,GO:0050662,GO:0050896,GO:0051716,GO:0055114,GO:0097159,GO:1901265,GO:1901363 - ko:K02846 - - - - ko00000,ko01000 - - iEC042_1314.EC042_1126 DAO k141_32893_6 1116375.VEJY3_22306 3.16e-44 144.0 COG0526@1|root,COG0526@2|Bacteria,1N728@1224|Proteobacteria,1SCEC@1236|Gammaproteobacteria,1XZ8N@135623|Vibrionales 135623|Vibrionales CO Thioredoxin domain - - - - - - - - - - - - Thioredoxin_3 k141_32893_7 1116375.VEJY3_22311 3.02e-127 369.0 COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,1RR9N@1236|Gammaproteobacteria,1XUEG@135623|Vibrionales 135623|Vibrionales S Predicted permease - - - ko:K07089 - - - - ko00000 - - - ArsP_1 k141_11733_1 1280001.BAOA01000060_gene2324 0.0 1821.0 COG3096@1|root,COG3096@2|Bacteria,1MUWM@1224|Proteobacteria,1RPFF@1236|Gammaproteobacteria,1XUHB@135623|Vibrionales 135623|Vibrionales D Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division mukB GO:0007059,GO:0008150,GO:0009987 - ko:K03632 - - - - ko00000,ko03036 - - - MukB,MukB_hinge,SbcCD_C k141_11733_2 1116375.VEJY3_04825 1.82e-126 367.0 COG2207@1|root,COG2207@2|Bacteria,1R5XR@1224|Proteobacteria,1S6MB@1236|Gammaproteobacteria,1XUBW@135623|Vibrionales 135623|Vibrionales K COG2207 AraC-type DNA-binding domain-containing proteins - - - - - - - - - - - - Arabinose_bd,HTH_18 k141_15076_1 697282.Mettu_3277 3.23e-77 259.0 COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,1RMW9@1236|Gammaproteobacteria,1XDIT@135618|Methylococcales 135618|Methylococcales G Glycosyl hydrolase 36 superfamily, catalytic domain - - - ko:K13688 - - - - ko00000,ko01000,ko01003 - GH94,GT84 - Glyco_hydro_36,Glyco_transf_36,Glycoamylase k141_29362_2 218284.CCDN010000001_gene1440 4.18e-31 109.0 2A051@1|root,30N7S@2|Bacteria,1UAQ6@1239|Firmicutes,4IM2V@91061|Bacilli,1ZIY8@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_29362_3 218284.CCDN010000001_gene1439 7.82e-07 49.7 COG4242@1|root,COG4242@2|Bacteria,1TSFA@1239|Firmicutes,4HF8K@91061|Bacilli,1ZEYR@1386|Bacillus 91061|Bacilli PQ Peptidase family S51 - - 3.4.15.6 ko:K13282 - - R09722 RC00064,RC00141 ko00000,ko01000,ko01002 - - - Peptidase_S51 k141_18998_1 218284.CCDN010000001_gene747 3.08e-122 357.0 COG0561@1|root,COG0561@2|Bacteria,1TR3N@1239|Firmicutes,4HC8P@91061|Bacilli,1ZBP7@1386|Bacillus 91061|Bacilli S Stage IV sporulation yqfD - - ko:K06438 - - - - ko00000 - - - YqfD k141_34196_1 218284.CCDN010000001_gene786 5.78e-97 293.0 COG0477@1|root,COG0477@2|Bacteria,1TTC8@1239|Firmicutes,4HAPZ@91061|Bacilli,1ZAQ7@1386|Bacillus 91061|Bacilli EGP Major facilitator superfamily yqgE - - ko:K08222 - - - - ko00000,ko02000 2.A.1.33 - - MFS_1 k141_15077_1 1137799.GZ78_09715 5.36e-28 111.0 28N4H@1|root,2ZB9Z@2|Bacteria,1PZPH@1224|Proteobacteria,1RQ43@1236|Gammaproteobacteria,1XIYP@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_5742_1 218284.CCDN010000002_gene2596 4.97e-94 288.0 COG4191@1|root,COG4191@2|Bacteria,1UZ9W@1239|Firmicutes,4HDK2@91061|Bacilli,1ZD85@1386|Bacillus 91061|Bacilli T Histidine kinase kinB - 2.7.13.3 ko:K07697 ko02020,map02020 M00485 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - 5TM-5TMR_LYT,HATPase_c,HisKA k141_26004_2 1294265.JCM21738_3607 9.89e-34 120.0 COG3543@1|root,COG3543@2|Bacteria,1VFVM@1239|Firmicutes,4HIWH@91061|Bacilli,1ZFNV@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF1284) - - - ko:K09706 - - - - ko00000 - - - DUF1284 k141_4385_1 218284.CCDN010000002_gene2063 9.14e-82 252.0 COG4129@1|root,COG4129@2|Bacteria,1UY2G@1239|Firmicutes,4HAWK@91061|Bacilli,1ZBAR@1386|Bacillus 91061|Bacilli S Aromatic acid exporter family member 1 - - - - - - - - - - - - ArAE_1 k141_22370_1 203122.Sde_3194 2.48e-33 126.0 COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,1RP7E@1236|Gammaproteobacteria,465AG@72275|Alteromonadaceae 1236|Gammaproteobacteria J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) gatA - 3.5.1.4,6.3.5.6,6.3.5.7 ko:K01426,ko:K02433 ko00330,ko00360,ko00380,ko00627,ko00643,ko00970,ko01100,ko01120,map00330,map00360,map00380,map00627,map00643,map00970,map01100,map01120 - R02540,R03096,R03180,R03905,R03909,R04212,R05551,R05590 RC00010,RC00100,RC00950,RC01025 ko00000,ko00001,ko01000,ko03029 - - - Amidase k141_22370_2 1042377.AFPJ01000030_gene471 3.15e-45 147.0 COG0721@1|root,COG0721@2|Bacteria,1MZQP@1224|Proteobacteria,1S8VY@1236|Gammaproteobacteria,467YW@72275|Alteromonadaceae 1236|Gammaproteobacteria J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatC - 6.3.5.6,6.3.5.7 ko:K02435 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Glu-tRNAGln k141_22370_4 1453501.JELR01000002_gene156 1.79e-145 414.0 COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,1RMK4@1236|Gammaproteobacteria,464KN@72275|Alteromonadaceae 1236|Gammaproteobacteria M Involved in formation and maintenance of cell shape mreC GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007163,GO:0008150,GO:0008360,GO:0009987,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0043621,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944,GO:0071963 - ko:K03570 - - - - ko00000,ko03036 9.B.157.1 - - MreC k141_22370_5 1453501.JELR01000002_gene155 4.92e-89 263.0 COG2891@1|root,COG2891@2|Bacteria,1RER7@1224|Proteobacteria,1S8VI@1236|Gammaproteobacteria,468E3@72275|Alteromonadaceae 1236|Gammaproteobacteria M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins mreD GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944 - ko:K03571 - - - - ko00000,ko03036 9.B.157.1 - - MreD k141_22370_6 5270.UM01151P0 0.000127 47.0 COG0424@1|root,COG0665@1|root,KOG1509@2759|Eukaryota,KOG3923@2759|Eukaryota,38DF2@33154|Opisthokonta,3NUSB@4751|Fungi,3V0EQ@5204|Basidiomycota,3N57J@452284|Ustilaginomycotina 4751|Fungi DE Maf-like protein - - - ko:K06287 - - - - ko00000 - - - Maf k141_19000_1 317655.Sala_2744 7.21e-12 72.4 COG1629@1|root,COG4771@2|Bacteria,1N6JG@1224|Proteobacteria,2TSK9@28211|Alphaproteobacteria,2K0T9@204457|Sphingomonadales 204457|Sphingomonadales P Carboxypeptidase regulatory-like domain - - - - - - - - - - - - CarboxypepD_reg,Plug,TonB_dep_Rec k141_26005_1 1525715.IX54_05180 7.36e-119 349.0 COG3328@1|root,COG3328@2|Bacteria,1MU4P@1224|Proteobacteria,2TUQT@28211|Alphaproteobacteria,2PV9X@265|Paracoccus 28211|Alphaproteobacteria L Transposase, Mutator family - - - - - - - - - - - - Transposase_mut k141_3191_1 1453501.JELR01000002_gene326 3.13e-215 619.0 COG1629@1|root,COG4206@1|root,COG4206@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria,464NB@72275|Alteromonadaceae 1236|Gammaproteobacteria P Outer membrane receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_35460_1 218284.CCDN010000002_gene2911 5.28e-152 430.0 COG0561@1|root,COG0561@2|Bacteria,1TR16@1239|Firmicutes,4HCZ6@91061|Bacilli,1ZCPY@1386|Bacillus 91061|Bacilli S hydrolases of the HAD superfamily ycsE - 3.1.3.104 ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R07280 RC00017 ko00000,ko00001,ko00002,ko01000 - - - Hydrolase_3 k141_6974_1 1121090.KB894685_gene3537 7.35e-115 355.0 COG2866@1|root,COG2866@2|Bacteria,1TSF6@1239|Firmicutes,4HDT5@91061|Bacilli,1ZBGR@1386|Bacillus 91061|Bacilli E Zinc carboxypeptidase - - - - - - - - - - - - Peptidase_M14 k141_16308_1 1294265.JCM21738_29 2.52e-63 195.0 COG2172@1|root,COG2172@2|Bacteria,1V6V2@1239|Firmicutes,4HGYN@91061|Bacilli,1ZFKS@1386|Bacillus 91061|Bacilli F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition spoIIAB GO:0000003,GO:0000988,GO:0000989,GO:0003674,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 2.7.11.1 ko:K06379 - - - - ko00000,ko01000 - - - HATPase_c_2 k141_16308_2 1294265.JCM21738_28 2.62e-74 223.0 COG1366@1|root,COG1366@2|Bacteria,1VENG@1239|Firmicutes,4HINR@91061|Bacilli,1ZGYC@1386|Bacillus 91061|Bacilli T Belongs to the anti-sigma-factor antagonist family spoIIAA - - ko:K06378 - - - - ko00000 - - - STAS k141_16308_3 1294265.JCM21738_27 4.46e-33 123.0 COG1686@1|root,COG1686@2|Bacteria,1TQN0@1239|Firmicutes,4HBCE@91061|Bacilli,1ZB0W@1386|Bacillus 91061|Bacilli M Belongs to the peptidase S11 family dacF GO:0003674,GO:0003824,GO:0004175,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.16.4 ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - PBP5_C,Peptidase_S11 k141_24697_1 218284.CCDN010000001_gene1229 4.39e-70 221.0 COG1876@1|root,COG1876@2|Bacteria,1V1F7@1239|Firmicutes,4HBR1@91061|Bacilli,1ZCAG@1386|Bacillus 91061|Bacilli M D-alanyl-D-alanine carboxypeptidase yodJ - 3.4.17.14 ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 M00651 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 - - - VanY k141_28000_1 674977.VMC_30040 7.44e-67 208.0 COG1842@1|root,COG1842@2|Bacteria,1NC7S@1224|Proteobacteria,1RS0G@1236|Gammaproteobacteria,1XUJH@135623|Vibrionales 135623|Vibrionales KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription pspA - - ko:K03969 - - - - ko00000 - - - PspA_IM30 k141_28000_2 223926.28806162 5.73e-42 138.0 2CJWQ@1|root,32YI2@2|Bacteria,1N769@1224|Proteobacteria,1SCNV@1236|Gammaproteobacteria,1XYAE@135623|Vibrionales 135623|Vibrionales S Phage shock protein B pspB - - ko:K03970 - - - - ko00000,ko02048 - - - PspB k141_28000_3 674977.VMC_30030 2.54e-78 234.0 COG1983@1|root,COG1983@2|Bacteria,1N085@1224|Proteobacteria,1S98J@1236|Gammaproteobacteria,1XXB4@135623|Vibrionales 135623|Vibrionales KT phage shock protein C pspC - - ko:K03973 - - - - ko00000,ko02048,ko03000 - - - PspC k141_28000_4 1116375.VEJY3_05750 5.98e-120 344.0 COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,1S25K@1236|Gammaproteobacteria,1XT91@135623|Vibrionales 135623|Vibrionales L COG2818 3-methyladenine DNA glycosylase tag - 3.2.2.20 ko:K01246 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Adenine_glyco k141_28000_5 1116375.VEJY3_05755 1.04e-285 781.0 COG0626@1|root,COG0626@2|Bacteria,1MU9E@1224|Proteobacteria,1RQI0@1236|Gammaproteobacteria,1XSKH@135623|Vibrionales 135623|Vibrionales E COG0626 Cystathionine beta-lyases cystathionine gamma-synthases metC - 4.4.1.8 ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko00002,ko01000 - - - Cys_Met_Meta_PP k141_28000_6 1116375.VEJY3_05760 0.0 915.0 COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,1RPQG@1236|Gammaproteobacteria,1XTMF@135623|Vibrionales 135623|Vibrionales I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol cls - - ko:K06131 ko00564,ko01100,map00564,map01100 - R07390 RC00017 ko00000,ko00001,ko01000 - - - PLDc_2,PLDc_N k141_5743_1 1294265.JCM21738_2699 6.75e-192 537.0 COG1071@1|root,COG1071@2|Bacteria,1TQDG@1239|Firmicutes,4H9PQ@91061|Bacilli,1ZBE0@1386|Bacillus 91061|Bacilli C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit pdhA - 1.2.4.1 ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh k141_31508_1 1116375.VEJY3_08015 5.06e-179 513.0 COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,1RPNE@1236|Gammaproteobacteria,1XSHH@135623|Vibrionales 135623|Vibrionales I AMP-binding enzyme - - - - - - - - - - - - AMP-binding k141_11759_2 1453501.JELR01000002_gene732 7.59e-66 212.0 COG4941@1|root,COG4941@2|Bacteria,1MU3D@1224|Proteobacteria,1RN25@1236|Gammaproteobacteria,46673@72275|Alteromonadaceae 1236|Gammaproteobacteria K RNA polymerase sigma factor containing a TPR repeat domain - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2,TPR_2 k141_9391_1 1219065.VPR01S_20_00190 4.27e-61 201.0 COG0582@1|root,COG0582@2|Bacteria,1MX7E@1224|Proteobacteria,1RNX5@1236|Gammaproteobacteria,1XV8P@135623|Vibrionales 135623|Vibrionales L Bacteriophage lambda integrase, Arm DNA-binding domain - - - - - - - - - - - - Arm-DNA-bind_1,Phage_integrase k141_1031_2 1347086.CCBA010000015_gene657 1.38e-31 112.0 COG0640@1|root,COG0640@2|Bacteria,1V9XT@1239|Firmicutes,4HKP8@91061|Bacilli,1ZI0T@1386|Bacillus 91061|Bacilli K ArsR family transcriptional regulator arsR GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - ko:K03892 - - - - ko00000,ko03000 - - - HTH_20,HTH_5 k141_20964_2 1279017.AQYJ01000019_gene1468 2.09e-302 827.0 COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,1RNJV@1236|Gammaproteobacteria,46418@72275|Alteromonadaceae 1236|Gammaproteobacteria U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently secY GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5 - - SecY k141_36378_1 1453501.JELR01000001_gene2897 6.33e-116 351.0 COG2010@1|root,COG2010@2|Bacteria,1MVYK@1224|Proteobacteria,1RQH2@1236|Gammaproteobacteria,465QC@72275|Alteromonadaceae 1236|Gammaproteobacteria C Cytochrome c - - - - - - - - - - - - - k141_37599_1 1121022.ABENE_00950 1.36e-09 64.3 COG1629@1|root,COG4206@1|root,COG1629@2|Bacteria,COG4206@2|Bacteria,1QU0Y@1224|Proteobacteria,2TZ5E@28211|Alphaproteobacteria,2KHUK@204458|Caulobacterales 204458|Caulobacterales HP Outer membrane protein beta-barrel family - - - - - - - - - - - - Plug,TonB_dep_Rec k141_33177_1 333138.LQ50_21815 2.13e-48 167.0 29H5Q@1|root,30439@2|Bacteria,1V63Q@1239|Firmicutes,4HHR2@91061|Bacilli,1ZE9T@1386|Bacillus 91061|Bacilli S Nuclease-related domain - - - - - - - - - - - - NERD k141_16582_2 1279017.AQYJ01000024_gene887 9.61e-74 227.0 COG1876@1|root,COG1876@2|Bacteria,1N2IC@1224|Proteobacteria,1S0DU@1236|Gammaproteobacteria,4679R@72275|Alteromonadaceae 1236|Gammaproteobacteria M D-alanyl-D-alanine carboxypeptidase vanY - - - - - - - - - - - VanY k141_34443_1 1280001.BAOA01000033_gene2227 9.46e-24 92.4 2DMHR@1|root,32RMI@2|Bacteria,1QK1W@1224|Proteobacteria,1TI4F@1236|Gammaproteobacteria,1XYCQ@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_34443_2 1268240.ATFI01000022_gene167 6.54e-33 118.0 2E4EA@1|root,32Z9I@2|Bacteria,4NTWC@976|Bacteroidetes,2FU6R@200643|Bacteroidia,4ARZ2@815|Bacteroidaceae 976|Bacteroidetes - - - - - - - - - - - - - - - k141_21310_1 545693.BMQ_4641 4.04e-198 554.0 COG0809@1|root,COG0809@2|Bacteria,1TPKD@1239|Firmicutes,4H9PT@91061|Bacilli,1ZB71@1386|Bacillus 91061|Bacilli J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) queA GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 ko:K07568 - - - - ko00000,ko01000,ko03016 - - - Queuosine_synth k141_33227_1 218284.CCDN010000001_gene1278 9.18e-182 516.0 COG4145@1|root,COG4145@2|Bacteria,1TQ1F@1239|Firmicutes,4HBKD@91061|Bacilli,1ZANP@1386|Bacillus 91061|Bacilli H Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family panF - - ko:K14392 - - - - ko00000,ko02000 2.A.21.1 - - SSF k141_33227_2 218284.CCDN010000001_gene1277 2.07e-28 103.0 COG3924@1|root,COG3924@2|Bacteria,1VAE9@1239|Firmicutes,4HKFU@91061|Bacilli,1ZICT@1386|Bacillus 91061|Bacilli S Sodium pantothenate symporter - - - - - - - - - - - - DUF997 k141_2298_1 1294265.JCM21738_396 3.41e-121 347.0 COG0558@1|root,COG0558@2|Bacteria,1V6PJ@1239|Firmicutes,4HCEX@91061|Bacilli,1ZBJ2@1386|Bacillus 91061|Bacilli I Belongs to the CDP-alcohol phosphatidyltransferase class-I family pgsA GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 2.7.8.5 ko:K00995 ko00564,ko01100,map00564,map01100 - R01801 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 - - iSB619.SA_RS06365 CDP-OH_P_transf k141_8129_1 759914.BP951000_1001 1.04e-10 61.6 COG0202@1|root,COG0202@2|Bacteria,2J58K@203691|Spirochaetes 203691|Spirochaetes K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoA - 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L k141_8129_2 663278.Ethha_0395 1.9e-37 132.0 COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,248Y5@186801|Clostridia,3WH6V@541000|Ruminococcaceae 186801|Clostridia J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit rpsD - - ko:K02986 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S4,S4 k141_30608_1 218284.CCDN010000001_gene941 8.18e-137 397.0 COG0403@1|root,COG0403@2|Bacteria,1TQGG@1239|Firmicutes,4HA7P@91061|Bacilli,1ZB0H@1386|Bacillus 91061|Bacilli E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor gcvPA - 1.4.4.2 ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 - R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko01000 - - - GDC-P k141_28347_1 218284.CCDN010000002_gene2102 1.36e-136 395.0 COG4120@1|root,COG4120@2|Bacteria,1TPDJ@1239|Firmicutes,4HBMY@91061|Bacilli,1ZAWA@1386|Bacillus 91061|Bacilli S Belongs to the binding-protein-dependent transport system permease family - - - ko:K05832 - M00247 - - ko00000,ko00002,ko02000 - - - BPD_transp_2 k141_21311_1 218284.CCDN010000008_gene4247 1.42e-134 409.0 COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H9SA@91061|Bacilli,1ZD7B@1386|Bacillus 91061|Bacilli M COG0744 Membrane carboxypeptidase (penicillin-binding protein) pbp1B - 2.4.1.129 ko:K03693,ko:K12551 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase k141_33228_1 10036.XP_005077746.1 6.65e-39 148.0 COG2303@1|root,KOG1238@2759|Eukaryota,38UEK@33154|Opisthokonta,3BBXZ@33208|Metazoa,3CRXP@33213|Bilateria,481AC@7711|Chordata,48W3C@7742|Vertebrata,3J28C@40674|Mammalia,35MA9@314146|Euarchontoglires,4Q3TW@9989|Rodentia 33208|Metazoa C choline dehydrogenase activity CHDH GO:0001505,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006576,GO:0006807,GO:0008150,GO:0008152,GO:0008812,GO:0009056,GO:0009308,GO:0009310,GO:0009987,GO:0016020,GO:0016491,GO:0016614,GO:0019695,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0042133,GO:0042135,GO:0042402,GO:0042426,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044106,GO:0044237,GO:0044248,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:0097164,GO:1901564,GO:1901565,GO:1901575 1.1.99.1 ko:K00108 ko00260,ko01100,map00260,map01100 M00555 R01025 RC00087 ko00000,ko00001,ko00002,ko01000 - - - GMC_oxred_C,GMC_oxred_N k141_37929_1 485913.Krac_9909 2.99e-24 102.0 COG0639@1|root,COG0639@2|Bacteria,2G8IP@200795|Chloroflexi 200795|Chloroflexi T Calcineurin-like phosphoesterase superfamily domain - - - - - - - - - - - - Metallophos_2 k141_21313_2 218284.CCDN010000002_gene2215 1.02e-10 60.5 2BE93@1|root,32804@2|Bacteria,1UAWI@1239|Firmicutes,4IM9C@91061|Bacilli,1ZJIH@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_33230_1 1453501.JELR01000002_gene855 6.63e-68 217.0 COG0260@1|root,COG0260@2|Bacteria,1MUIN@1224|Proteobacteria,1RNFI@1236|Gammaproteobacteria,465XH@72275|Alteromonadaceae 1236|Gammaproteobacteria E Probably plays an important role in intracellular peptide degradation pepB - 3.4.11.23 ko:K07751 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - DUF3663,Peptidase_M17 k141_28350_1 218284.CCDN010000001_gene1334 1.13e-152 442.0 COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HAHB@91061|Bacilli,1ZPZR@1386|Bacillus 91061|Bacilli IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II yngI - - ko:K00666 - - - - ko00000,ko01000,ko01004 - - - AMP-binding,AMP-binding_C k141_2302_1 1453501.JELR01000002_gene1273 5.4e-121 364.0 COG1505@1|root,COG1505@2|Bacteria,1NZ7N@1224|Proteobacteria,1T1KJ@1236|Gammaproteobacteria,46621@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG1505 Serine proteases of the peptidase family S9A - - 3.4.21.26 ko:K01322 ko04614,map04614 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S9,Peptidase_S9_N k141_8132_1 218284.CCDN010000002_gene2903 2.79e-190 537.0 COG2270@1|root,COG2270@2|Bacteria,1TRTH@1239|Firmicutes,4H9VB@91061|Bacilli,1ZDX4@1386|Bacillus 91061|Bacilli S COG2270 Permeases of the major facilitator superfamily yxiO - - ko:K06902 ko04138,map04138 - - - ko00000,ko00001,ko02000,ko04131 2.A.1.24,9.A.15.1 - - ATG22 k141_34479_2 1279017.AQYJ01000027_gene1717 5.12e-129 376.0 COG1721@1|root,COG1721@2|Bacteria,1MWPG@1224|Proteobacteria,1S4TD@1236|Gammaproteobacteria,46B1X@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function DUF58 - - - - - - - - - - - - DUF58 k141_34479_3 1122603.ATVI01000007_gene1711 1.83e-06 58.2 28JTF@1|root,2Z9IQ@2|Bacteria,1R728@1224|Proteobacteria,1SJF5@1236|Gammaproteobacteria,1X4II@135614|Xanthomonadales 135614|Xanthomonadales S Aerotolerance regulator N-terminal - - - - - - - - - - - - BatA k141_21314_1 218284.CCDN010000002_gene2857 2.11e-44 152.0 COG5482@1|root,COG5482@2|Bacteria,1V3FI@1239|Firmicutes,4HI6C@91061|Bacilli,1ZDPW@1386|Bacillus 91061|Bacilli S Putative PD-(D/E)XK phosphodiesterase (DUF2161) - - - - - - - - - - - - DUF2161 k141_21314_2 1423321.AS29_09085 9.15e-110 332.0 COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TPJ8@1239|Firmicutes,4HA8X@91061|Bacilli,1ZAZ3@1386|Bacillus 91061|Bacilli G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific nagE - 2.7.1.193,2.7.1.199 ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 M00267,M00809 R02738,R05199 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.13,4.A.1.1.14,4.A.1.1.15,4.A.1.1.2,4.A.1.1.5,4.A.1.1.7,4.A.1.1.9 - iSB619.SA_RS08720 PTS_EIIA_1,PTS_EIIB,PTS_EIIC k141_15302_1 378806.STAUR_6796 2.05e-88 276.0 COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,42NDS@68525|delta/epsilon subdivisions,2WJDE@28221|Deltaproteobacteria,2YZC9@29|Myxococcales 28221|Deltaproteobacteria S RmuC family - - - ko:K09760 - - - - ko00000 - - - RmuC k141_33232_1 1294265.JCM21738_3125 2.39e-10 59.7 COG1173@1|root,COG1173@2|Bacteria,1V7EU@1239|Firmicutes,4HJGN@91061|Bacilli,1ZFJU@1386|Bacillus 91061|Bacilli EP ABC-type dipeptide oligopeptide nickel transport systems, permease components - - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 k141_33232_2 441769.ABFU01000040_gene3008 1.66e-12 66.2 2DKHE@1|root,309GB@2|Bacteria,1U50R@1239|Firmicutes,4IESM@91061|Bacilli,1ZI04@1386|Bacillus 91061|Bacilli S Intracellular proteinase inhibitor - - - - - - - - - - - - BsuPI k141_34480_1 1894.JOER01000045_gene6692 2.12e-05 48.9 COG0494@1|root,COG0494@2|Bacteria,2ISBX@201174|Actinobacteria 201174|Actinobacteria L Belongs to the NUDIX hydrolase family - - 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - - NUDIX k141_36618_1 493475.GARC_2930 7.14e-110 339.0 COG1228@1|root,COG1228@2|Bacteria,1RCA0@1224|Proteobacteria,1S08B@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q COG1228 Imidazolonepropionase and related amidohydrolases - - - - - - - - - - - - Amidohydro_1,CIA30 k141_30612_1 1117379.BABA_04639 7.96e-86 270.0 COG0770@1|root,COG0770@2|Bacteria,1UPUZ@1239|Firmicutes,4HTD6@91061|Bacilli,1ZQ3G@1386|Bacillus 91061|Bacilli M Mur ligase family, glutamate ligase domain - - 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 - R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase_C,Mur_ligase_M k141_33234_1 935948.KE386494_gene539 1.95e-66 216.0 COG2256@1|root,COG2256@2|Bacteria,1TPVV@1239|Firmicutes,247X2@186801|Clostridia,42FF6@68295|Thermoanaerobacterales 186801|Clostridia L AAA ATPase, central domain protein rarA - - ko:K07478 - - - - ko00000 - - - AAA,AAA_assoc_2,MgsA_C,RuvB_N k141_4693_1 223926.28808534 1.98e-76 239.0 COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,1RPKC@1236|Gammaproteobacteria,1XVI5@135623|Vibrionales 135623|Vibrionales J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) tyrS1 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006437,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - S4,tRNA-synt_1b k141_4693_2 1116375.VEJY3_16921 2.59e-243 669.0 COG0687@1|root,COG0687@2|Bacteria,1MUYW@1224|Proteobacteria,1RM7W@1236|Gammaproteobacteria,1XUI9@135623|Vibrionales 135623|Vibrionales P Required for the activity of the bacterial periplasmic transport system of putrescine - - - ko:K11069 ko02010,map02010 M00299 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 - - SBP_bac_8 k141_4693_3 1280001.BAOA01000045_gene1680 4.63e-33 116.0 2AWM7@1|root,31NHY@2|Bacteria,1QK8Q@1224|Proteobacteria,1TIC6@1236|Gammaproteobacteria,1XYUS@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_4693_4 1116375.VEJY3_16886 0.0 947.0 COG1292@1|root,COG1292@2|Bacteria,1MV0K@1224|Proteobacteria,1RRSQ@1236|Gammaproteobacteria,1XT8W@135623|Vibrionales 135623|Vibrionales M Belongs to the BCCT transporter (TC 2.A.15) family - - - - - - - - - - - - BCCT k141_4693_5 1116375.VEJY3_16851 9.71e-145 409.0 COG0560@1|root,COG0560@2|Bacteria,1RA1A@1224|Proteobacteria,1S21J@1236|Gammaproteobacteria,1XSWS@135623|Vibrionales 135623|Vibrionales E COG0560 Phosphoserine phosphatase - - - - - - - - - - - - HAD k141_28354_2 765912.Thimo_0714 3.06e-82 249.0 COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,1S237@1236|Gammaproteobacteria,1WWYK@135613|Chromatiales 135613|Chromatiales P Reversible hydration of carbon dioxide - - 4.2.1.1 ko:K01673 ko00910,map00910 - R00132,R10092 RC02807 ko00000,ko00001,ko01000 - - - Pro_CA k141_36619_1 666686.B1NLA3E_06520 5.76e-59 192.0 COG0045@1|root,COG0045@2|Bacteria,1TQG4@1239|Firmicutes,4HA3W@91061|Bacilli,1ZB9P@1386|Bacillus 91061|Bacilli C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit sucC GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 6.2.1.5 ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU16090 ATP-grasp_2,Ligase_CoA k141_8134_1 1117647.M5M_16130 4.1e-07 52.4 COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,1RMT7@1236|Gammaproteobacteria,1J52J@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - DUF885 k141_37932_2 1116375.VEJY3_24276 7.52e-47 150.0 2AWRF@1|root,31NND@2|Bacteria,1QKCY@1224|Proteobacteria,1TIGI@1236|Gammaproteobacteria,1XZ39@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_37932_3 1219076.N646_3429 5.37e-104 301.0 COG1522@1|root,COG1522@2|Bacteria,1RE7N@1224|Proteobacteria,1S56G@1236|Gammaproteobacteria,1XUPJ@135623|Vibrionales 135623|Vibrionales K COG1522 Transcriptional regulators - - - ko:K03719 - - - - ko00000,ko03000,ko03036 - - - AsnC_trans_reg,HTH_24 k141_4694_1 1347369.CCAD010000049_gene440 2.12e-72 229.0 COG1304@1|root,COG1304@2|Bacteria,1TQZ3@1239|Firmicutes,4HAMV@91061|Bacilli,1ZCXC@1386|Bacillus 91061|Bacilli C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) fni GO:0003674,GO:0003824,GO:0004452,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016853,GO:0016860,GO:0016863,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0071704,GO:1901576 5.3.3.2 ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095,M00096,M00364,M00365,M00366,M00367 R01123 RC00455 ko00000,ko00001,ko00002,ko01000 - - - FMN_dh k141_28355_1 218284.CCDN010000002_gene2939 2.45e-119 348.0 COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,4HA4E@91061|Bacilli,1ZB72@1386|Bacillus 91061|Bacilli P Belongs to the ABC transporter superfamily - - - ko:K02031 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - ABC_tran,oligo_HPY k141_37933_1 218284.CCDN010000006_gene3757 1.37e-94 288.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,4HCDP@91061|Bacilli,1ZD3N@1386|Bacillus 91061|Bacilli E Glutamate/Leucine/Phenylalanine/Valine dehydrogenase gdhA - 1.4.1.3 ko:K00261 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 M00740 R00243,R00248 RC00006,RC02799 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ELFV_dehydrog,ELFV_dehydrog_N k141_8136_1 592316.Pat9b_3795 2.87e-37 137.0 COG0435@1|root,COG0435@2|Bacteria,1MV50@1224|Proteobacteria,1RMTI@1236|Gammaproteobacteria,3VYH6@53335|Pantoea 1236|Gammaproteobacteria O Glutathione S-Transferase - - 1.8.5.7 ko:K07393 - - - - ko00000,ko01000 - - - GST_C_2,GST_N_2 k141_33235_3 1127673.GLIP_2702 8.95e-19 84.3 COG1595@1|root,COG1595@2|Bacteria 2|Bacteria K DNA-templated transcription, initiation - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_28357_1 218284.CCDN010000002_gene2185 1.93e-121 354.0 COG2130@1|root,COG2130@2|Bacteria,1TQUE@1239|Firmicutes,4HCHY@91061|Bacilli,1ZC4N@1386|Bacillus 91061|Bacilli S N-terminal domain of oxidoreductase yfmJ - - ko:K07119 - - - - ko00000 - - - ADH_N_2,ADH_zinc_N k141_3491_1 1279017.AQYJ01000018_gene772 0.0 1503.0 COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,1RMWZ@1236|Gammaproteobacteria,465GZ@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain alaS GO:0001130,GO:0001131,GO:0001141,GO:0001217,GO:0002161,GO:0002196,GO:0003674,GO:0003700,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006355,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009451,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019219,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0052689,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:0140110,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iECABU_c1320.ECABU_c29670,iECED1_1282.ECED1_3146,iEcHS_1320.EcHS_A2833,iJN746.PP_4474 DHHA1,tRNA-synt_2c,tRNA_SAD k141_3491_4 1279017.AQYJ01000018_gene775 1.42e-102 307.0 COG2267@1|root,COG2267@2|Bacteria,1MWF5@1224|Proteobacteria,1RNQR@1236|Gammaproteobacteria,46CDV@72275|Alteromonadaceae 1236|Gammaproteobacteria I Serine aminopeptidase, S33 ynbC GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0008150,GO:0008152,GO:0016020,GO:0016298,GO:0016787,GO:0016788,GO:0044238,GO:0071704 - - - - - - - - - - Hydrolase_4,Methyltransf_20 k141_3491_5 1279017.AQYJ01000018_gene776 1.66e-180 509.0 COG3588@1|root,COG3588@2|Bacteria,1MVFK@1224|Proteobacteria,1RQ57@1236|Gammaproteobacteria,469X9@72275|Alteromonadaceae 1236|Gammaproteobacteria G Fructose-bisphosphate aldolase class-I alf1 - 4.1.2.13 ko:K01623 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000,ko03036,ko04131,ko04147 - - - Glycolytic k141_3491_6 1279017.AQYJ01000018_gene777 1.6e-273 758.0 COG0554@1|root,COG0554@2|Bacteria,1MUP7@1224|Proteobacteria,1RMAF@1236|Gammaproteobacteria,464DH@72275|Alteromonadaceae 1236|Gammaproteobacteria C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate glpK GO:0003674,GO:0003824,GO:0004370,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019405,GO:0019563,GO:0019751,GO:0033554,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046164,GO:0046174,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:1901575,GO:1901615,GO:1901616 2.7.1.30 ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 - R00847 RC00002,RC00017 ko00000,ko00001,ko01000,ko04147 - - iE2348C_1286.E2348C_4230,iECNA114_1301.ECNA114_4065,iECSF_1327.ECSF_3786 FGGY_C,FGGY_N k141_3491_8 1042377.AFPJ01000025_gene586 8.7e-233 642.0 COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,1RMHP@1236|Gammaproteobacteria,465M8@72275|Alteromonadaceae 1236|Gammaproteobacteria L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage recA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K03553 ko03440,map03440 M00729 - - ko00000,ko00001,ko00002,ko03400 - - - RecA k141_3491_10 1279017.AQYJ01000018_gene808 0.0 1417.0 COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,1RNW3@1236|Gammaproteobacteria,464F1@72275|Alteromonadaceae 1236|Gammaproteobacteria L that it carries out the mismatch recognition step. This protein has a weak ATPase activity mutS GO:0000018,GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0008301,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030554,GO:0030983,GO:0031323,GO:0032136,GO:0032300,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1990391 - ko:K03555 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - iECW_1372.ECW_m2935,iWFL_1372.ECW_m2935 MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V k141_3491_13 1279017.AQYJ01000018_gene812 1.25e-64 203.0 COG2128@1|root,COG2128@2|Bacteria 2|Bacteria S hydroperoxide reductase activity - - - - - - - - - - - - CMD k141_3491_14 1453501.JELR01000001_gene2815 2.22e-202 566.0 COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,1RMFM@1236|Gammaproteobacteria,464UA@72275|Alteromonadaceae 1236|Gammaproteobacteria L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII dinB GO:0003674,GO:0003824,GO:0003887,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02346 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH k141_3491_15 522373.Smlt3211 4.47e-07 50.4 2ANYG@1|root,31DZF@2|Bacteria,1QB9H@1224|Proteobacteria,1T6TX@1236|Gammaproteobacteria,1X857@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - k141_3491_16 87626.PTD2_04506 0.000865 46.6 COG1595@1|root,COG1595@2|Bacteria,1N38X@1224|Proteobacteria,1SASQ@1236|Gammaproteobacteria,2Q35E@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4,Sigma70_r4_2 k141_3491_18 1279017.AQYJ01000018_gene818 6.04e-63 197.0 COG2030@1|root,COG2030@2|Bacteria,1RHPH@1224|Proteobacteria,1S72R@1236|Gammaproteobacteria,4682E@72275|Alteromonadaceae 1236|Gammaproteobacteria I MaoC like domain - - - - - - - - - - - - MaoC_dehydratas k141_3491_19 1279017.AQYJ01000018_gene819 1.11e-124 362.0 COG1028@1|root,COG1028@2|Bacteria,1R413@1224|Proteobacteria,1RSKB@1236|Gammaproteobacteria,4667I@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ Short-chain dehydrogenase reductase sDR - - - - - - - - - - - - adh_short_C2 k141_3491_20 1279017.AQYJ01000018_gene820 1.89e-159 449.0 COG1028@1|root,COG1028@2|Bacteria,1MWGC@1224|Proteobacteria,1RRE1@1236|Gammaproteobacteria,4644A@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) HA62_15005 - - - - - - - - - - - adh_short_C2 k141_3491_21 1279017.AQYJ01000018_gene821 5.03e-190 535.0 COG3173@1|root,COG3173@2|Bacteria,1MWAK@1224|Proteobacteria,1RNB4@1236|Gammaproteobacteria,465F2@72275|Alteromonadaceae 1236|Gammaproteobacteria S Aminoglycoside phosphotransferase - - - - - - - - - - - - APH k141_3491_23 236097.ADG881_2083 2.55e-70 221.0 COG0406@1|root,COG0406@2|Bacteria,1RB0S@1224|Proteobacteria,1S2YG@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Phosphoglycerate mutase - - - - - - - - - - - - His_Phos_1 k141_3491_24 1279017.AQYJ01000018_gene824 7.81e-160 454.0 COG0583@1|root,COG0583@2|Bacteria,1NYPZ@1224|Proteobacteria,1RXYS@1236|Gammaproteobacteria,46558@72275|Alteromonadaceae 1236|Gammaproteobacteria K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_3491_25 1279017.AQYJ01000018_gene825 1.29e-190 546.0 COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,1RNM8@1236|Gammaproteobacteria,4656A@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family fadH - 1.3.1.34 ko:K00219 - - - - ko00000,ko01000 - - - Oxidored_FMN,Pyr_redox_2 k141_2307_1 365659.smi_0434 1.03e-94 288.0 COG0270@1|root,COG0270@2|Bacteria,1TS3G@1239|Firmicutes,4IPYS@91061|Bacilli,2TQI2@28037|Streptococcus mitis 91061|Bacilli H C-5 cytosine-specific DNA methylase - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k141_37935_1 1294265.JCM21738_2263 3.81e-97 287.0 COG0510@1|root,COG0510@2|Bacteria,1UMFY@1239|Firmicutes,4HBF9@91061|Bacilli,1ZC4H@1386|Bacillus 91061|Bacilli M Phosphotransferase ytmP - - - - - - - - - - - APH k141_37935_2 1294265.JCM21738_2262 3.8e-37 127.0 COG1523@1|root,COG1523@2|Bacteria 2|Bacteria G belongs to the glycosyl hydrolase 13 family pulA - 3.2.1.41 ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 - R02111 - ko00000,ko00001,ko01000 - CBM48,GH13 - Alpha-amylase,CBM_48 k141_21376_1 1116375.VEJY3_01520 0.0 876.0 COG0729@1|root,COG0729@2|Bacteria,1MUKM@1224|Proteobacteria,1RNQ3@1236|Gammaproteobacteria,1XV1N@135623|Vibrionales 135623|Vibrionales M COG0729 Outer membrane protein ytfM - - ko:K07278 - - - - ko00000,ko02000 1.B.33.2.4 - - Bac_surface_Ag,POTRA,POTRA_TamA_1 k141_21376_2 1116375.VEJY3_01515 1.13e-135 385.0 COG0225@1|root,COG0225@2|Bacteria,1MVUS@1224|Proteobacteria,1RNWU@1236|Gammaproteobacteria,1XU05@135623|Vibrionales 135623|Vibrionales O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine msrA GO:0003674,GO:0003824,GO:0006807,GO:0008113,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016667,GO:0016671,GO:0019538,GO:0030091,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0055114,GO:0071704,GO:1901564 1.8.4.11 ko:K07304 - - - - ko00000,ko01000 - - - PMSR k141_21376_3 1116375.VEJY3_01510 1.17e-32 114.0 2CTIP@1|root,32STK@2|Bacteria,1MZ8V@1224|Proteobacteria,1S908@1236|Gammaproteobacteria,1XYV1@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF1107) - - - - - - - - - - - - DUF1107 k141_30654_1 1294265.JCM21738_1777 1.72e-112 334.0 COG0303@1|root,COG0303@2|Bacteria,1UJ4G@1239|Firmicutes 1239|Firmicutes H MoeA domain protein domain I and II - - 2.10.1.1 ko:K03750,ko:K07219 ko00790,ko01100,map00790,map01100 - R09735 RC03462 ko00000,ko00001,ko01000 - - - MoCF_biosynth,MoeA_C,MoeA_N,PBP_like k141_37966_1 218284.CCDN010000002_gene2878 6.43e-88 276.0 COG2268@1|root,COG2268@2|Bacteria,1TQDT@1239|Firmicutes,4HA0C@91061|Bacilli,1ZBTE@1386|Bacillus 91061|Bacilli S protein conserved in bacteria yuaG - - ko:K07192 ko04910,map04910 - - - ko00000,ko00001,ko03036,ko04131,ko04147 - - - Band_7,Flot k141_36681_2 1116375.VEJY3_07225 1.96e-24 93.2 2EH97@1|root,33B11@2|Bacteria,1NHPA@1224|Proteobacteria,1SGUW@1236|Gammaproteobacteria,1XYW7@135623|Vibrionales 135623|Vibrionales S TIGRFAM formate dehydrogenase region TAT target - - - - - - - - - - - - TAT_signal k141_36681_3 1116375.VEJY3_07230 0.0 1699.0 COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,1MW3N@1224|Proteobacteria,1RN6N@1236|Gammaproteobacteria,1XTH6@135623|Vibrionales 135623|Vibrionales C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family fdhA - 1.17.1.9 ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001,ko01000 - - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding k141_31796_1 1323663.AROI01000015_gene578 9.85e-32 125.0 COG0534@1|root,COG0534@2|Bacteria,1MUAM@1224|Proteobacteria,1RP5M@1236|Gammaproteobacteria 1236|Gammaproteobacteria V Multidrug efflux pump pmpM - - ko:K03327 - - - - ko00000,ko02000 2.A.66.1 - - MatE k141_30655_1 218284.CCDN010000001_gene1206 2.32e-122 350.0 COG4698@1|root,COG4698@2|Bacteria,1VF0K@1239|Firmicutes,4HIYN@91061|Bacilli,1ZF26@1386|Bacillus 91061|Bacilli S protein conserved in bacteria ypmS - - - - - - - - - - - DUF2140 k141_30655_2 218284.CCDN010000001_gene1207 1.74e-06 48.5 COG1404@1|root,COG1404@2|Bacteria,1V3SC@1239|Firmicutes,4HGZF@91061|Bacilli,1ZGVY@1386|Bacillus 91061|Bacilli O Domain of unknown function (DUF4397) - - - - - - - - - - - - DUF4397 k141_21378_1 240302.BN982_03272 7.15e-99 300.0 COG0019@1|root,COG0019@2|Bacteria,1TPE9@1239|Firmicutes,4HAPF@91061|Bacilli,3ND2E@45667|Halobacillus 91061|Bacilli E Pyridoxal-dependent decarboxylase, pyridoxal binding domain - - 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS00750 Orn_Arg_deC_N,Orn_DAP_Arg_deC k141_37968_1 218284.CCDN010000001_gene514 6.72e-126 374.0 COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,4H9VY@91061|Bacilli,1ZCDT@1386|Bacillus 91061|Bacilli G Belongs to the pyruvate kinase family pyk GO:0001871,GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0030246,GO:0030247,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:2001065 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - PEP-utilizers,PK,PK_C k141_15346_1 331869.BAL199_10410 3.89e-89 273.0 COG2132@1|root,COG2132@2|Bacteria,1MXT2@1224|Proteobacteria,2VF0D@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q Multicopper oxidase - - - - - - - - - - - - Cu-oxidase_2,Cu-oxidase_3 k141_14430_3 1279017.AQYJ01000020_gene1329 7.94e-132 374.0 COG0231@1|root,COG0231@2|Bacteria,1MW2J@1224|Proteobacteria,1RPW7@1236|Gammaproteobacteria,465T7@72275|Alteromonadaceae 1236|Gammaproteobacteria J Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of efp GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006417,GO:0006448,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0072344,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112,GO:2000113,GO:2001124,GO:2001125 - ko:K02356 - - - - ko00000,ko03012 - - - EFP,EFP_N,Elong-fact-P_C k141_15628_1 218284.CCDN010000007_gene3790 2e-42 139.0 COG2501@1|root,COG2501@2|Bacteria,1VEJ2@1239|Firmicutes,4HNMC@91061|Bacilli,1ZIXZ@1386|Bacillus 91061|Bacilli S S4 domain yaaA - - ko:K14761 - - - - ko00000,ko03009 - - - S4_2 k141_15628_2 218284.CCDN010000007_gene3789 5.27e-168 475.0 COG1195@1|root,COG1195@2|Bacteria,1TP9U@1239|Firmicutes,4HA0W@91061|Bacilli,1ZC8V@1386|Bacillus 91061|Bacilli L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP recF GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - ko:K03629 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - SMC_N k141_3730_1 313603.FB2170_11101 1.74e-67 216.0 COG4221@1|root,COG4221@2|Bacteria,4NGKR@976|Bacteroidetes,1HYM0@117743|Flavobacteriia 976|Bacteroidetes S Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short k141_6129_1 935836.JAEL01000083_gene1124 5.87e-225 633.0 COG1620@1|root,COG1620@2|Bacteria,1TQNM@1239|Firmicutes,4HAF3@91061|Bacilli,1ZC0U@1386|Bacillus 91061|Bacilli C L-lactate permease - - - ko:K03303 - - - - ko00000,ko02000 2.A.14 - - Lactate_perm k141_7261_2 218284.CCDN010000001_gene1193 3.78e-80 239.0 28NYH@1|root,2ZBVN@2|Bacteria,1V1T3@1239|Firmicutes,4HHZS@91061|Bacilli,1ZGM0@1386|Bacillus 91061|Bacilli S Belongs to the UPF0403 family yphP - - - - - - - - - - - Disulph_isomer k141_1267_1 1294265.JCM21738_1830 9.31e-58 179.0 COG2350@1|root,COG2350@2|Bacteria,1VIFB@1239|Firmicutes,4HSHF@91061|Bacilli 91061|Bacilli S YCII-related domain - - - - - - - - - - - - YCII k141_1267_2 1294265.JCM21738_1829 1.87e-15 77.8 COG3468@1|root,COG3468@2|Bacteria 2|Bacteria MU cell adhesion - - - ko:K18491 ko04550,map04550 - - - ko00000,ko00001,ko03000 - - - Collagen,DUF4132,Gln_amidase k141_14431_1 283942.IL1591 3.38e-69 210.0 COG0346@1|root,COG0346@2|Bacteria,1RHM9@1224|Proteobacteria,1S6Y3@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Glyoxalase bleomycin resistance protein dioxygenase - - - - - - - - - - - - Glyoxalase k141_2536_1 1128421.JAGA01000003_gene3640 6.45e-26 97.8 2DJKR@1|root,32YT5@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k141_2536_2 1279017.AQYJ01000023_gene3245 3.47e-17 80.5 COG2836@1|root,COG2836@2|Bacteria,1RIGJ@1224|Proteobacteria,1S5V1@1236|Gammaproteobacteria,466TY@72275|Alteromonadaceae 1236|Gammaproteobacteria S Cytochrome C biogenesis protein transmembrane region braZ - - ko:K09792 - - - - ko00000 - - - DsbD_2 k141_15629_1 218284.CCDN010000001_gene1214 3.23e-100 303.0 COG0161@1|root,COG0161@2|Bacteria,1TP9N@1239|Firmicutes,4HD8E@91061|Bacilli,1ZAWS@1386|Bacillus 91061|Bacilli H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family yodT - - - - - - - - - - - Aminotran_3 k141_8481_2 1116375.VEJY3_06410 3.36e-236 653.0 COG3129@1|root,COG3129@2|Bacteria,1MUI4@1224|Proteobacteria,1RMVA@1236|Gammaproteobacteria,1XTU3@135623|Vibrionales 135623|Vibrionales J Specifically methylates the adenine in position 1618 of 23S rRNA rlmF GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008988,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052907,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.181 ko:K06970 - - R07232 RC00003,RC00335 ko00000,ko01000,ko03009 - - - Methyltransf_10 k141_8481_6 1116375.VEJY3_06465 9.84e-163 457.0 COG1120@1|root,COG1120@2|Bacteria,1MVKU@1224|Proteobacteria,1RN86@1236|Gammaproteobacteria,1XVHM@135623|Vibrionales 135623|Vibrionales HP ABC-type cobalamin Fe3 -siderophores transport systems, ATPase - - 3.6.3.34 ko:K02013 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 - - ABC_tran k141_8481_7 1116375.VEJY3_06470 1.02e-197 552.0 COG0609@1|root,COG0609@2|Bacteria,1MV9W@1224|Proteobacteria,1RMST@1236|Gammaproteobacteria,1XSQQ@135623|Vibrionales 135623|Vibrionales P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily - - - ko:K02015 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - FecCD k141_6130_2 1150469.RSPPHO_00238 1.09e-13 71.2 COG0687@1|root,COG0687@2|Bacteria,1MUYW@1224|Proteobacteria,2TSUZ@28211|Alphaproteobacteria,2JPA2@204441|Rhodospirillales 204441|Rhodospirillales E Required for the activity of the bacterial periplasmic transport system of putrescine - - - ko:K11069,ko:K11073 ko02010,map02010 M00299,M00300 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.1,3.A.1.11.2 - - SBP_bac_8 k141_23879_2 1294265.JCM21738_4225 1.62e-21 85.1 2ET7S@1|root,33KRT@2|Bacteria,1VP54@1239|Firmicutes,4HRRC@91061|Bacilli,1ZIUE@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2553) yusG - - - - - - - - - - - DUF2553 k141_29836_1 218284.CCDN010000002_gene2886 2.4e-211 594.0 COG0277@1|root,COG0277@2|Bacteria,1TPBC@1239|Firmicutes,4H9UU@91061|Bacilli,1ZCQN@1386|Bacillus 91061|Bacilli C Glycolate oxidase subunit dld - 1.1.2.4,1.1.3.15 ko:K00102,ko:K00104 ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130 - R00197,R00475 RC00042,RC00044 ko00000,ko00001,ko01000 - - - FAD-oxidase_C,FAD_binding_4 k141_14432_1 218284.CCDN010000004_gene3156 1.22e-10 60.5 COG0561@1|root,COG0561@2|Bacteria,1V2XI@1239|Firmicutes,4HG2U@91061|Bacilli,1ZB1F@1386|Bacillus 91061|Bacilli S hydrolases of the HAD superfamily yhaX - - - - - - - - - - - Hydrolase_3 k141_14432_2 218284.CCDN010000004_gene3155 1.43e-58 183.0 COG3679@1|root,COG3679@2|Bacteria,1VASS@1239|Firmicutes,4HKKC@91061|Bacilli,1ZH14@1386|Bacillus 91061|Bacilli S Belongs to the UPF0342 family yheA - - - - - - - - - - - Com_YlbF k141_7262_1 1279017.AQYJ01000022_gene2741 5.35e-46 157.0 COG2853@1|root,COG2853@2|Bacteria,1MVX0@1224|Proteobacteria,1RNPS@1236|Gammaproteobacteria,466E2@72275|Alteromonadaceae 1236|Gammaproteobacteria M Surface lipoprotein vacJ - - ko:K04754 - - - - ko00000 - - - MlaA k141_10800_1 218284.CCDN010000012_gene4442 2.07e-163 466.0 COG1388@1|root,COG3858@1|root,COG1388@2|Bacteria,COG3858@2|Bacteria,1TQK2@1239|Firmicutes,4HBJC@91061|Bacilli,1ZBQC@1386|Bacillus 91061|Bacilli M Glycoside Hydrolase Family yaaH - - ko:K06306 - - - - ko00000 - - - Glyco_hydro_18,LysM k141_18020_1 766499.C357_13395 9.02e-84 251.0 COG3108@1|root,COG3108@2|Bacteria,1MWW2@1224|Proteobacteria,2TQZ1@28211|Alphaproteobacteria 28211|Alphaproteobacteria NU Protein conserved in bacteria - - - - - - - - - - - - Peptidase_M15_2 k141_27447_1 218284.CCDN010000003_gene2992 5.28e-105 316.0 COG1694@1|root,COG3956@2|Bacteria,1TPK1@1239|Firmicutes,4HA0A@91061|Bacilli,1ZAYB@1386|Bacillus 91061|Bacilli S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like yabN GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.66 ko:K02428,ko:K02499 ko00230,map00230 - R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000,ko03036 - - - MazG,TP_methylase k141_34624_2 1116375.VEJY3_19506 5.6e-163 457.0 COG1296@1|root,COG1296@2|Bacteria,1Q43G@1224|Proteobacteria,1RPZB@1236|Gammaproteobacteria,1XWAV@135623|Vibrionales 135623|Vibrionales E AzlC protein - - - - - - - - - - - - AzlC k141_22737_3 1279017.AQYJ01000028_gene2197 5.97e-57 199.0 COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,1RP9N@1236|Gammaproteobacteria,464DC@72275|Alteromonadaceae 1236|Gammaproteobacteria H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell glnE GO:0000166,GO:0000287,GO:0000820,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006521,GO:0006541,GO:0006542,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0008882,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0010565,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0019222,GO:0019752,GO:0030554,GO:0031323,GO:0032553,GO:0032555,GO:0032559,GO:0033238,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.42,2.7.7.89 ko:K00982 - - - - ko00000,ko01000 - - - GlnD_UR_UTase,GlnE k141_26327_2 218284.CCDN010000001_gene1131 1.63e-62 193.0 COG1694@1|root,COG1694@2|Bacteria,1V701@1239|Firmicutes,4HISK@91061|Bacilli,1ZH1U@1386|Bacillus 91061|Bacilli S Nucleotide pyrophosphohydrolase ypjD - - - - - - - - - - - MazG k141_13246_2 1042377.AFPJ01000037_gene2915 5.38e-225 625.0 COG0624@1|root,COG0624@2|Bacteria,1MW6G@1224|Proteobacteria,1RMNQ@1236|Gammaproteobacteria,4650N@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls dapE GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009014,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20 k141_7263_1 1042377.AFPJ01000014_gene1638 2.46e-92 275.0 COG2135@1|root,COG2135@2|Bacteria,1RCCC@1224|Proteobacteria,1S39B@1236|Gammaproteobacteria,46737@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the SOS response-associated peptidase family - - - - - - - - - - - - SRAP k141_14434_1 1128421.JAGA01000002_gene1230 2.59e-40 150.0 COG0699@1|root,COG0699@2|Bacteria,2NQN2@2323|unclassified Bacteria 2|Bacteria S Dynamin family - - - - - - - - - - - - Dynamin_N k141_197_2 223926.28808694 1.62e-131 374.0 COG0179@1|root,COG0179@2|Bacteria,1MVFA@1224|Proteobacteria,1S8KH@1236|Gammaproteobacteria,1XTE3@135623|Vibrionales 135623|Vibrionales Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) - - - - - - - - - - - - FAA_hydrolase k141_32195_4 945543.VIBR0546_02504 6.44e-237 659.0 COG0226@1|root,COG0226@2|Bacteria,1PGT2@1224|Proteobacteria,1RRXV@1236|Gammaproteobacteria,1XWB9@135623|Vibrionales 135623|Vibrionales P T5orf172 - - - - - - - - - - - - MUG113,T5orf172 k141_16781_1 1517681.HW45_22490 1.31e-92 283.0 COG1706@1|root,COG1706@2|Bacteria,1MVKW@1224|Proteobacteria,1RMRB@1236|Gammaproteobacteria,1XUVU@135623|Vibrionales 135623|Vibrionales N Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation - - - ko:K02394 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FlgI k141_28721_1 218284.CCDN010000001_gene1267 5.52e-98 286.0 COG0054@1|root,COG0054@2|Bacteria,1V1DA@1239|Firmicutes,4HFRA@91061|Bacilli,1ZFJ6@1386|Bacillus 91061|Bacilli H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin ribH GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R04457 RC00960 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS08940 DMRL_synthase k141_21588_1 218284.CCDN010000007_gene4020 3.72e-75 232.0 COG4786@1|root,COG4786@2|Bacteria,1TRFQ@1239|Firmicutes,4HCKG@91061|Bacilli,1ZBEC@1386|Bacillus 91061|Bacilli N flagellar basal body flhO GO:0001539,GO:0005575,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009424,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588 - ko:K02392 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C k141_36965_1 218284.CCDN010000001_gene970 1.25e-88 264.0 COG1253@1|root,COG1253@2|Bacteria,1VBH3@1239|Firmicutes,4HFR4@91061|Bacilli,1ZEWH@1386|Bacillus 91061|Bacilli S flavin adenine dinucleotide binding - - - - - - - - - - - - - k141_9637_1 675814.VIC_001635 4.78e-294 821.0 COG1215@1|root,COG1215@2|Bacteria,1P7GR@1224|Proteobacteria,1RNP2@1236|Gammaproteobacteria,1XURS@135623|Vibrionales 135623|Vibrionales M Glycosyltransferase like family 2 - - - ko:K11740 - - - - ko00000 - - - Glyco_trans_2_3,T2SSE_N k141_211_1 1294265.JCM21738_3955 2.93e-199 556.0 COG0680@1|root,COG0680@2|Bacteria,1TPFY@1239|Firmicutes,4HAGH@91061|Bacilli,1ZC4A@1386|Bacillus 91061|Bacilli C Initiates the rapid degradation of small, acid-soluble proteins during spore germination gpr GO:0000003,GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019954,GO:0030436,GO:0032502,GO:0043170,GO:0043934,GO:0044238,GO:0071704,GO:0140096,GO:1901564 3.4.24.78 ko:K06012 - - - - ko00000,ko01000,ko01002 - - - Peptidase_A25 k141_12025_1 1265503.KB905169_gene269 2.37e-11 64.7 COG2755@1|root,COG2755@2|Bacteria,1QRM7@1224|Proteobacteria,1SNZ4@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Pfam:DUF303 - - - - - - - - - - - - SASA k141_2548_1 1042377.AFPJ01000028_gene2158 1.59e-132 401.0 COG2755@1|root,COG2755@2|Bacteria,1MXTS@1224|Proteobacteria,1RTPH@1236|Gammaproteobacteria,46419@72275|Alteromonadaceae 1236|Gammaproteobacteria E Concanavalin A-like lectin/glucanases superfamily - - - - - - - - - - - - Laminin_G_3 k141_19144_1 1234664.AMRO01000024_gene1890 3.92e-32 118.0 COG0584@1|root,COG0584@2|Bacteria,1V3W4@1239|Firmicutes,4HFNQ@91061|Bacilli,1WEGT@129337|Geobacillus 91061|Bacilli C Glycerophosphoryl diester phosphodiesterase family yqiK - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - GDPD k141_27456_1 1123405.AUMM01000026_gene2155 2.58e-41 148.0 COG1285@1|root,COG1285@2|Bacteria,1V409@1239|Firmicutes,4HC2G@91061|Bacilli,26PQC@186821|Sporolactobacillaceae 91061|Bacilli S MgtC family mgtC3 - - ko:K07507 - - - - ko00000,ko02000 9.B.20 - - MgtC k141_27456_2 218284.CCDN010000005_gene3496 1.02e-125 363.0 COG1285@1|root,COG1285@2|Bacteria,1V409@1239|Firmicutes,4HGHY@91061|Bacilli,1ZBY0@1386|Bacillus 91061|Bacilli S MgtC SapB transporter sapB - - ko:K07507 - - - - ko00000,ko02000 9.B.20 - - MgtC k141_27456_3 218284.CCDN010000005_gene3497 7.19e-177 498.0 COG0697@1|root,COG0697@2|Bacteria,1TR1G@1239|Firmicutes,4HB57@91061|Bacilli,1ZCN9@1386|Bacillus 91061|Bacilli EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - - - - - - - - - - EamA k141_27456_4 649639.Bcell_2845 6.36e-20 85.9 COG1247@1|root,COG1247@2|Bacteria,1VAAC@1239|Firmicutes,4HKUR@91061|Bacilli,1ZHWJ@1386|Bacillus 91061|Bacilli M FR47-like protein - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10,FR47 k141_15642_1 218284.CCDN010000001_gene1685 2.25e-169 505.0 COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,4HC3Y@91061|Bacilli,1ZCCY@1386|Bacillus 91061|Bacilli V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family yerP1 - - - - - - - - - - - ACR_tran k141_13253_2 1279017.AQYJ01000025_gene733 2.42e-39 145.0 COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,1RNCU@1236|Gammaproteobacteria,464IX@72275|Alteromonadaceae 1236|Gammaproteobacteria L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd GO:0000715,GO:0000716,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006283,GO:0006289,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008094,GO:0008150,GO:0008152,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0015616,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031326,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0043175,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051276,GO:0051716,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF k141_32196_1 1453501.JELR01000002_gene920 1.41e-70 217.0 COG1272@1|root,COG1272@2|Bacteria,1PGRH@1224|Proteobacteria,1RR4R@1236|Gammaproteobacteria,467AP@72275|Alteromonadaceae 1236|Gammaproteobacteria S membrane protein, hemolysin III homolog yqfA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K11068 - - - - ko00000,ko02042 - - - HlyIII k141_32196_2 1232410.KI421428_gene1151 3.78e-05 45.1 2AI77@1|root,318MJ@2|Bacteria,1MXJB@1224|Proteobacteria,430PU@68525|delta/epsilon subdivisions,2WW3I@28221|Deltaproteobacteria 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k141_22741_1 1116375.VEJY3_23951 2.37e-109 325.0 COG0665@1|root,COG0665@2|Bacteria,1MU7M@1224|Proteobacteria,1RP7W@1236|Gammaproteobacteria,1XWHB@135623|Vibrionales 135623|Vibrionales E FAD dependent oxidoreductase - - - - - - - - - - - - DAO k141_22741_2 1116375.VEJY3_23946 8.85e-304 832.0 COG0531@1|root,COG0531@2|Bacteria,1R4PP@1224|Proteobacteria,1RP8U@1236|Gammaproteobacteria,1Y00J@135623|Vibrionales 135623|Vibrionales E Amino acid permease - - - - - - - - - - - - AA_permease_2 k141_22741_3 1116375.VEJY3_23921 4.61e-272 746.0 COG0019@1|root,COG0019@2|Bacteria,1MZ7Y@1224|Proteobacteria,1RQJ4@1236|Gammaproteobacteria,1XVHW@135623|Vibrionales 135623|Vibrionales E Pyridoxal-dependent decarboxylase, pyridoxal binding domain - - 4.1.1.17 ko:K01581 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 M00134 R00670 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N,Orn_DAP_Arg_deC k141_22741_4 1116375.VEJY3_23916 2.14e-204 567.0 COG0583@1|root,COG0583@2|Bacteria,1QYAP@1224|Proteobacteria,1RYE8@1236|Gammaproteobacteria,1XU6I@135623|Vibrionales 135623|Vibrionales K COG0583 Transcriptional regulator - - - ko:K21699 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate k141_22741_5 1116375.VEJY3_23911 7.13e-307 837.0 COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,1RP0C@1236|Gammaproteobacteria,1XW4I@135623|Vibrionales 135623|Vibrionales E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - 2.6.1.18 ko:K00822 ko00280,ko00410,ko00640,ko01100,map00280,map00410,map00640,map01100 - R00907,R04187 RC00008,RC00062,RC00160 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_3 k141_18035_1 1071073.KI530537_gene2481 3.88e-71 229.0 COG0025@1|root,COG0025@2|Bacteria,1TR4G@1239|Firmicutes,4HBJR@91061|Bacilli,1ZQCF@1386|Bacillus 91061|Bacilli P Sodium/hydrogen exchanger family - - - ko:K03316 - - - - ko00000 2.A.36 - - Na_H_Exchanger k141_31097_1 1453501.JELR01000002_gene1321 7.08e-36 129.0 COG2197@1|root,COG2197@2|Bacteria 2|Bacteria K response regulator - - - - - - - - - - - - GerE,PAS_3 k141_31097_2 1453501.JELR01000002_gene1320 3.02e-77 231.0 COG3651@1|root,COG3651@2|Bacteria,1RH68@1224|Proteobacteria,1S7KX@1236|Gammaproteobacteria,46CDB@72275|Alteromonadaceae 1236|Gammaproteobacteria S Uncharacterized protein conserved in bacteria (DUF2237) - - - ko:K09966 - - - - ko00000 - - - DUF2237 k141_23889_1 1033734.CAET01000054_gene1432 6.98e-95 289.0 COG1524@1|root,COG1524@2|Bacteria,1TRZ7@1239|Firmicutes,4HAY5@91061|Bacilli,1ZD4Z@1386|Bacillus 91061|Bacilli S type I phosphodiesterase nucleotide pyrophosphatase npp - - - - - - - - - - - Phosphodiest k141_12026_1 179408.Osc7112_3710 2.38e-23 100.0 COG3878@1|root,COG3878@2|Bacteria,1G5GT@1117|Cyanobacteria,1HBQ0@1150|Oscillatoriales 1117|Cyanobacteria S Domain of unknown function (DUF1963) - - - - - - - - - - - - DUF1963 k141_7280_1 1294265.JCM21738_5261 2.04e-16 79.3 COG4715@1|root,COG4715@2|Bacteria,1TS1R@1239|Firmicutes,4HHDK@91061|Bacilli,1ZEXD@1386|Bacillus 91061|Bacilli S Zinc finger, swim domain protein - - - - - - - - - - - - SWIM k141_7280_2 1294265.JCM21738_5497 9.59e-62 192.0 COG4087@1|root,COG4087@2|Bacteria,1VA72@1239|Firmicutes,4IIJM@91061|Bacilli,1ZNNZ@1386|Bacillus 91061|Bacilli S Soluble P-type ATPase - - - - - - - - - - - - - k141_33405_2 318161.Sden_0438 6.64e-18 84.0 COG0823@1|root,COG0823@2|Bacteria,1N4BQ@1224|Proteobacteria,1T0KT@1236|Gammaproteobacteria,2QDCD@267890|Shewanellaceae 1236|Gammaproteobacteria U WD40-like Beta Propeller Repeat - - - - - - - - - - - - PD40 k141_25072_1 1501230.ET33_14120 4.81e-18 90.9 COG0661@1|root,COG0661@2|Bacteria,1TPIV@1239|Firmicutes,4HBW3@91061|Bacilli,26TIV@186822|Paenibacillaceae 91061|Bacilli S ABC transporter ubiB - - ko:K03688 - - - - ko00000 - - - ABC1,APH k141_25072_2 1078085.HMPREF1210_01028 6.34e-28 107.0 2F4M5@1|root,33XAN@2|Bacteria,1UNPW@1239|Firmicutes,4IUJY@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - k141_3745_1 1340434.AXVA01000016_gene701 4.07e-25 97.4 2E3WX@1|root,32YU3@2|Bacteria,1VFHJ@1239|Firmicutes,4HPQ5@91061|Bacilli,1ZITX@1386|Bacillus 91061|Bacilli - - yozC - - - - - - - - - - - - k141_3745_2 218284.CCDN010000001_gene1340 4.69e-91 274.0 COG0714@1|root,COG0714@2|Bacteria,1TQJA@1239|Firmicutes,4HBG4@91061|Bacilli,1ZAT6@1386|Bacillus 91061|Bacilli S ATPase family associated with various cellular activities (AAA) yojN - - ko:K04748 - - R00294 RC02794 ko00000 3.D.4.10 - - AAA_5,CbbQ_C k141_13254_2 265729.GS18_0220255 3.04e-22 95.1 COG2972@1|root,COG2972@2|Bacteria,1UU89@1239|Firmicutes,4HECK@91061|Bacilli,1ZAUI@1386|Bacillus 91061|Bacilli T Histidine kinase - - 2.7.13.3 ko:K07718 ko02020,map02020 M00519 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,His_kinase,dCache_1 k141_14437_1 223926.28807045 1.12e-28 111.0 COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria,1XSPH@135623|Vibrionales 135623|Vibrionales I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP fabF GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.179 ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt k141_14437_2 1280001.BAOA01000086_gene3559 8.41e-158 446.0 COG0115@1|root,COG0115@2|Bacteria,1MZAK@1224|Proteobacteria,1RPPG@1236|Gammaproteobacteria,1XSWU@135623|Vibrionales 135623|Vibrionales EH COG0115 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase pabC GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008696,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0034641,GO:0042558,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0046483,GO:0051186,GO:0071704,GO:1901360,GO:1901564 4.1.3.38 ko:K02619 ko00790,map00790 - R05553 RC01843,RC02148 ko00000,ko00001,ko01000 - - - Aminotran_4 k141_14437_3 1116375.VEJY3_10665 3.9e-208 579.0 COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,1RMWD@1236|Gammaproteobacteria,1XTTP@135623|Vibrionales 135623|Vibrionales S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation mltG - - ko:K07082 - - - - ko00000 - - - YceG k141_14437_4 1116375.VEJY3_10660 3.51e-131 374.0 COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,1S26C@1236|Gammaproteobacteria,1XTND@135623|Vibrionales 135623|Vibrionales F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis tmk GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 ko:K00943 ko00240,ko01100,map00240,map01100 M00053 R02094,R02098 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Thymidylate_kin k141_14437_5 1116375.VEJY3_10655 5.76e-201 560.0 COG0470@1|root,COG0470@2|Bacteria,1R9U1@1224|Proteobacteria,1T1C8@1236|Gammaproteobacteria,1Y31R@135623|Vibrionales 135623|Vibrionales L DNA polymerase III subunit delta holB - 2.7.7.7 ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNApol3-delta_C k141_14437_6 1219076.N646_1123 4.39e-168 471.0 COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,1RP6E@1236|Gammaproteobacteria,1XTHX@135623|Vibrionales 135623|Vibrionales L COG0084 Mg-dependent DNase ycfH - - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase k141_14437_7 29495.EA26_16110 0.0 880.0 COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1MY1V@1224|Proteobacteria,1RMYZ@1236|Gammaproteobacteria,1XV6P@135623|Vibrionales 135623|Vibrionales G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific ptsG - 2.7.1.199 ko:K02778,ko:K02779 ko00010,ko00520,ko02060,ko05111,map00010,map00520,map02060,map05111 M00265 R02738 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.1 - - PTS_EIIB,PTS_EIIC k141_14437_8 1116375.VEJY3_10630 2.01e-77 231.0 2E0KP@1|root,32W5Z@2|Bacteria,1N1JH@1224|Proteobacteria,1SA3K@1236|Gammaproteobacteria,1XY21@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_14437_9 1280001.BAOA01000086_gene3552 2.69e-12 60.1 2AWZ9@1|root,31NX5@2|Bacteria,1QKKJ@1224|Proteobacteria,1TIQW@1236|Gammaproteobacteria,1XZH1@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_14437_10 1116375.VEJY3_10620 0.0 929.0 COG0733@1|root,COG0733@2|Bacteria,1MUZJ@1224|Proteobacteria,1RPCT@1236|Gammaproteobacteria,1XU8H@135623|Vibrionales 135623|Vibrionales U Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family - - - ko:K03308 - - - - ko00000 2.A.22.4,2.A.22.5 - - SNF k141_14437_11 1116375.VEJY3_10610 2.13e-06 45.4 2AY04@1|root,31Q1P@2|Bacteria,1QMQ9@1224|Proteobacteria,1TJZY@1236|Gammaproteobacteria,1Y1WQ@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_14437_12 1116375.VEJY3_10605 5.31e-264 724.0 COG4667@1|root,COG4667@2|Bacteria,1NU6Q@1224|Proteobacteria,1SKPI@1236|Gammaproteobacteria,1XUVM@135623|Vibrionales 135623|Vibrionales S esterase of the alpha-beta hydrolase superfamily - - - - - - - - - - - - Patatin k141_14437_13 223926.28807032 2.31e-313 857.0 COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,1RMW3@1236|Gammaproteobacteria,1XSQD@135623|Vibrionales 135623|Vibrionales G Belongs to the pyruvate kinase family pykA - 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - PK,PK_C k141_33577_1 1294265.JCM21738_3667 3.85e-102 302.0 COG0115@1|root,COG0115@2|Bacteria,1TSIP@1239|Firmicutes,4HC7K@91061|Bacilli,1ZCRC@1386|Bacillus 91061|Bacilli EH 4-amino-4-deoxychorismate lyase pabC - 4.1.3.38 ko:K02619 ko00790,map00790 - R05553 RC01843,RC02148 ko00000,ko00001,ko01000 - - - Aminotran_4 k141_33577_2 1294265.JCM21738_3668 7.45e-24 96.3 COG0294@1|root,COG0294@2|Bacteria,1TPKT@1239|Firmicutes,4H9SY@91061|Bacilli,1ZAPZ@1386|Bacillus 91061|Bacilli H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives folP GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.15 ko:K00796 ko00790,ko01100,map00790,map01100 M00126,M00841 R03066,R03067 RC00121,RC00842 ko00000,ko00001,ko00002,ko01000 - - - Pterin_bind k141_25282_1 223926.28806263 1.06e-104 310.0 COG0010@1|root,COG0010@2|Bacteria,1NCRN@1224|Proteobacteria,1RNKI@1236|Gammaproteobacteria,1XV0K@135623|Vibrionales 135623|Vibrionales E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide hutG GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016813,GO:0019439,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0052803,GO:0052805,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.3.8 ko:K01479 ko00340,ko01100,map00340,map01100 M00045 R02285 RC00221,RC00681 ko00000,ko00001,ko00002,ko01000 - - - Arginase k141_26628_1 218284.CCDN010000001_gene552 1.69e-68 215.0 COG1039@1|root,COG1039@2|Bacteria,1TQBE@1239|Firmicutes,4H9QR@91061|Bacilli,1ZBHW@1386|Bacillus 91061|Bacilli L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhC GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03471 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DUF3378,RNase_HII k141_26628_2 218284.CCDN010000001_gene553 9.99e-47 150.0 COG3027@1|root,COG3027@2|Bacteria,1VFZR@1239|Firmicutes,4HNRI@91061|Bacilli,1ZHZX@1386|Bacillus 91061|Bacilli D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division zapA - - ko:K09888 - - - - ko00000,ko03036 - - - ZapA k141_13429_1 1453501.JELR01000002_gene1518 9.13e-86 271.0 COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,1RPF7@1236|Gammaproteobacteria,46550@72275|Alteromonadaceae 1236|Gammaproteobacteria CO Thiol disulfide interchange protein dsbD - 1.8.1.8 ko:K04084 - - - - ko00000,ko01000,ko03110 5.A.1.1 - - DsbC,DsbD,Thioredoxin_7 k141_5047_1 575540.Isop_2569 2.55e-57 193.0 COG0499@1|root,COG0499@2|Bacteria,2IXKQ@203682|Planctomycetes 203682|Planctomycetes H May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine ahcY - 3.3.1.1 ko:K01251 ko00270,ko01100,map00270,map01100 M00035 R00192,R04936 RC00056,RC00069,RC01161,RC01243 ko00000,ko00001,ko00002,ko01000,ko01009,ko04147 - - - AdoHcyase,AdoHcyase_NAD k141_24057_1 1279017.AQYJ01000027_gene1981 1.28e-108 337.0 COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,1RPFM@1236|Gammaproteobacteria,4673P@72275|Alteromonadaceae 1236|Gammaproteobacteria M protein involved in outer membrane biogenesis asmA - - ko:K07289 - - - - ko00000 - - - AsmA k141_27574_1 218284.CCDN010000006_gene3609 3.29e-194 558.0 COG0557@1|root,COG0557@2|Bacteria,1TQ1G@1239|Firmicutes,4HBBH@91061|Bacilli,1ZBDP@1386|Bacillus 91061|Bacilli K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs rnr - - ko:K12573 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03016,ko03019 - - - OB_RNB,RNB,S1 k141_9808_1 1280001.BAOA01000076_gene3276 3.38e-34 123.0 2CA3C@1|root,3336E@2|Bacteria,1NH8Y@1224|Proteobacteria,1SI0F@1236|Gammaproteobacteria,1Y33P@135623|Vibrionales 135623|Vibrionales S Flagellar protein YcgR - - - - - - - - - - - - PilZ,YcgR_2 k141_3954_1 1294265.JCM21738_4574 9.63e-107 321.0 COG2812@1|root,COG2812@2|Bacteria,1TPS9@1239|Firmicutes,4HAUE@91061|Bacilli,1ZB2M@1386|Bacillus 91061|Bacilli L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity dnaX GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNA_pol3_gamma3 k141_14547_1 218284.CCDN010000002_gene2855 0.0 909.0 COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1TQ0B@1239|Firmicutes,4HA4G@91061|Bacilli,1ZBFF@1386|Bacillus 91061|Bacilli E glutamate synthase gltA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14,1.4.7.1 ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 - R00021,R00093,R00114,R00248,R10086 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - GATase_2,GXGXG,Glu_syn_central,Glu_synthase k141_33592_2 223926.28806857 1.84e-197 551.0 COG0582@1|root,COG0582@2|Bacteria,1QUFZ@1224|Proteobacteria,1T1XN@1236|Gammaproteobacteria,1XUVH@135623|Vibrionales 135623|Vibrionales L Belongs to the 'phage' integrase family intIA - - - - - - - - - - - Phage_int_SAM_4,Phage_integrase k141_33592_3 1116375.VEJY3_09930 9.79e-110 315.0 2AQ2U@1|root,31F7Z@2|Bacteria,1R8TD@1224|Proteobacteria,1S0VX@1236|Gammaproteobacteria,1XWZE@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF2947) VV12273 - - - - - - - - - - - DUF2947 k141_33592_4 1116375.VEJY3_09935 8.79e-127 362.0 COG1896@1|root,COG1896@2|Bacteria,1MXEZ@1224|Proteobacteria,1RRQQ@1236|Gammaproteobacteria,1XUSC@135623|Vibrionales 135623|Vibrionales S hydrolases of HD superfamily - - - ko:K07023 - - - - ko00000 - - - HD_3 k141_2716_1 1403313.AXBR01000024_gene4757 3.1e-90 280.0 COG1167@1|root,COG1167@2|Bacteria,1TPS5@1239|Firmicutes,4HB1C@91061|Bacilli,1ZASA@1386|Bacillus 91061|Bacilli K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs ydfD - - ko:K18907 - M00700,M00702 - - ko00000,ko00002,ko01504,ko03000 - - - Aminotran_1_2,GntR k141_34779_1 1196028.ALEF01000060_gene1202 2.25e-85 264.0 COG2141@1|root,COG2141@2|Bacteria,1TQZ0@1239|Firmicutes,4HAF9@91061|Bacilli,4C55W@84406|Virgibacillus 91061|Bacilli C Luciferase-like monooxygenase - - 1.14.14.28 ko:K20938 - - - - ko00000,ko01000 - - - Bac_luciferase k141_21729_1 1294265.JCM21738_3397 5.34e-38 127.0 2BX75@1|root,32YR8@2|Bacteria,1VJMT@1239|Firmicutes,4HP70@91061|Bacilli,1ZIU2@1386|Bacillus 91061|Bacilli S small acid-soluble spore protein sspD - - ko:K06421 - - - - ko00000 - - - SASP k141_26639_2 1294265.JCM21738_2086 4.23e-23 90.5 COG1393@1|root,COG1393@2|Bacteria,1V73M@1239|Firmicutes,4HJDP@91061|Bacilli,1ZHC6@1386|Bacillus 91061|Bacilli P Belongs to the ArsC family yqgZ - 1.20.4.1 ko:K00537,ko:K16509 - - - - ko00000,ko01000 - - - ArsC k141_10995_1 1279017.AQYJ01000020_gene1281 2.87e-113 342.0 COG0705@1|root,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,1RZ5Q@1236|Gammaproteobacteria,46767@72275|Alteromonadaceae 1236|Gammaproteobacteria S membrane protein (homolog of Drosophila rhomboid) - - - - - - - - - - - - Rhomboid k141_10995_2 1453501.JELR01000002_gene856 1.02e-69 227.0 COG1040@1|root,COG1040@2|Bacteria,1REX9@1224|Proteobacteria,1S568@1236|Gammaproteobacteria,4671D@72275|Alteromonadaceae 1236|Gammaproteobacteria S competence protein - - - - - - - - - - - - - k141_1455_1 1453501.JELR01000001_gene2972 3.74e-06 46.6 2C6YA@1|root,33M7P@2|Bacteria,1NJUZ@1224|Proteobacteria,1SJ0Y@1236|Gammaproteobacteria,46C67@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_1455_2 1453501.JELR01000001_gene2971 5.59e-180 506.0 COG1090@1|root,COG1090@2|Bacteria,1MUB4@1224|Proteobacteria,1RN6A@1236|Gammaproteobacteria,465A2@72275|Alteromonadaceae 1236|Gammaproteobacteria S nucleoside-diphosphate sugar epimerase yfcH - - ko:K07071 - - - - ko00000 - - - DUF1731,Epimerase k141_37095_1 1453501.JELR01000001_gene3215 9.19e-32 123.0 COG3707@1|root,COG3707@2|Bacteria,1MXDV@1224|Proteobacteria,1RMQG@1236|Gammaproteobacteria,464HH@72275|Alteromonadaceae 1236|Gammaproteobacteria K Nitrate-and nitrite-responsive positive regulator nasR - - - - - - - - - - - ANTAR,NIT k141_19317_2 1116375.VEJY3_10975 1.96e-58 185.0 COG3531@1|root,COG3531@2|Bacteria,1RIN9@1224|Proteobacteria,1RS8P@1236|Gammaproteobacteria,1XUUK@135623|Vibrionales 135623|Vibrionales O Protein-disulfide isomerase VP2116 - - ko:K07396 - - - - ko00000 - - - Thioredoxin_5 k141_14548_1 218284.CCDN010000001_gene990 2.38e-101 314.0 COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,1TQAD@1239|Firmicutes,4H9QB@91061|Bacilli,1ZCKD@1386|Bacillus 91061|Bacilli I COG1884 Methylmalonyl-CoA mutase, N-terminal domain subunit mutB - 5.4.99.2 ko:K01847 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00373,M00376,M00741 R00833 RC00395 ko00000,ko00001,ko00002,ko01000 - - - B12-binding,MM_CoA_mutase k141_26640_1 1444309.JAQG01000181_gene3480 5.32e-06 53.1 COG1172@1|root,COG1172@2|Bacteria,1TP72@1239|Firmicutes,4H9Y3@91061|Bacilli,26R5U@186822|Paenibacillaceae 91061|Bacilli G Belongs to the binding-protein-dependent transport system permease family rbsC - - ko:K10440 ko02010,map02010 M00212 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - BPD_transp_2 k141_35931_1 240302.BN982_00040 6.25e-118 352.0 COG0477@1|root,COG2814@2|Bacteria,1TPRN@1239|Firmicutes,4H9VV@91061|Bacilli,3NDKW@45667|Halobacillus 91061|Bacilli EGP Major Facilitator Superfamily lmrB - - ko:K18926 - M00715 - - ko00000,ko00002,ko02000 2.A.1.3.30 - - MFS_1 k141_18216_1 439235.Dalk_2019 4.8e-49 164.0 COG1943@1|root,COG1943@2|Bacteria,1RIWM@1224|Proteobacteria,42SBY@68525|delta/epsilon subdivisions,2WPSK@28221|Deltaproteobacteria,2MM75@213118|Desulfobacterales 28221|Deltaproteobacteria L IMG reference gene - - - - - - - - - - - - Y1_Tnp k141_10996_1 326423.RBAM_004320 7.3e-56 187.0 COG1984@1|root,COG1984@2|Bacteria,1TR6U@1239|Firmicutes,4HACC@91061|Bacilli,1ZCFE@1386|Bacillus 91061|Bacilli E Allophanate hydrolase subunit 2 kipA - - ko:K06350 - - - - ko00000 - - - CT_A_B k141_3956_1 218284.CCDN010000001_gene967 1.43e-138 403.0 COG1570@1|root,COG1570@2|Bacteria,1TP4E@1239|Firmicutes,4HAN2@91061|Bacilli,1ZB5Q@1386|Bacillus 91061|Bacilli L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseA - 3.1.11.6 ko:K03601 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_L,tRNA_anti_2 k141_12299_1 218284.CCDN010000002_gene2296 4.58e-183 517.0 COG3182@1|root,COG3182@2|Bacteria,1TSD4@1239|Firmicutes,4HDAS@91061|Bacilli,1ZCZS@1386|Bacillus 91061|Bacilli S PepSY-associated TM region - - - - - - - - - - - - PepSY,PepSY_TM k141_21730_1 218284.CCDN010000006_gene3737 3.26e-119 345.0 COG1464@1|root,COG1464@2|Bacteria,1TRXS@1239|Firmicutes,4HAD4@91061|Bacilli,1ZBWI@1386|Bacillus 91061|Bacilli P COG1464 ABC-type metal ion transport system, periplasmic component surface antigen - - - ko:K02073 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - Lipoprotein_9 k141_8640_1 42565.FP66_15250 1.05e-70 239.0 COG2911@1|root,COG2911@2|Bacteria,1MUVD@1224|Proteobacteria,1RMMF@1236|Gammaproteobacteria,1XJGI@135619|Oceanospirillales 135619|Oceanospirillales S protein conserved in bacteria - - - ko:K09800 - - - - ko00000,ko02000 - - - TamB k141_1456_1 218284.CCDN010000005_gene3462 1.85e-112 332.0 COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,4HA13@91061|Bacilli,1ZAWQ@1386|Bacillus 91061|Bacilli E Aminotransferase yugH - - ko:K10907 - - - - ko00000,ko01000,ko01007 - - - Aminotran_1_2 k141_27575_1 218284.CCDN010000002_gene2265 3.7e-35 124.0 COG0454@1|root,COG0456@2|Bacteria,1VBS5@1239|Firmicutes,4HKDH@91061|Bacilli,1ZFR4@1386|Bacillus 91061|Bacilli K Acetyltransferase (GNAT) family - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10 k141_27575_2 218284.CCDN010000002_gene2266 6.09e-39 142.0 COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,1TPXQ@1239|Firmicutes,4HA3C@91061|Bacilli,1ZBHE@1386|Bacillus 91061|Bacilli C Catalyzes the reversible hydration of fumarate to (S)- malate fumA - 4.2.1.2 ko:K01676 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - - Fumerase,Fumerase_C k141_33593_1 1279017.AQYJ01000029_gene3685 3.8e-43 151.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RW1Q@1236|Gammaproteobacteria,4663X@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1960 Acyl-CoA dehydrogenases atuD - - ko:K11731 ko00281,map00281 - R08089 RC01893 ko00000,ko00001,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_33593_2 1279017.AQYJ01000029_gene3684 2.99e-72 228.0 COG1024@1|root,COG1024@2|Bacteria,1MVEC@1224|Proteobacteria,1RP85@1236|Gammaproteobacteria,4670X@72275|Alteromonadaceae 1236|Gammaproteobacteria I enoyl-CoA hydratase atuE - 4.2.1.57 ko:K13779 ko00281,map00281 - R03493 RC00941 ko00000,ko00001,ko01000 - - - ECH_1 k141_26641_1 315730.BcerKBAB4_2199 4.08e-18 87.0 COG0601@1|root,COG0601@2|Bacteria,1V1H8@1239|Firmicutes,4HGD5@91061|Bacilli 91061|Bacilli P Binding-protein-dependent transport system inner membrane component - - - ko:K02033 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 k141_34780_1 1185653.A1A1_03567 3.78e-10 61.2 2BJ57@1|root,32DEE@2|Bacteria,1V93H@1239|Firmicutes,4HK2X@91061|Bacilli,26F4U@186818|Planococcaceae 91061|Bacilli S Protein of unknown function (DUF1510) - - - - - - - - - - - - DUF1510 k141_34780_3 218284.CCDN010000008_gene4138 1.19e-74 229.0 COG1734@1|root,COG1734@2|Bacteria,1V4KF@1239|Firmicutes,4HHBC@91061|Bacilli,1ZQQT@1386|Bacillus 91061|Bacilli T Prokaryotic dksA/traR C4-type zinc finger - - - - - - - - - - - - zf-dskA_traR k141_14549_1 981383.AEWH01000068_gene364 8.27e-57 180.0 COG0454@1|root,COG0456@2|Bacteria,1VF9B@1239|Firmicutes,4HR9Z@91061|Bacilli 91061|Bacilli K FR47-like protein - - - - - - - - - - - - Acetyltransf_1 k141_20457_2 265729.GS18_0210795 1.64e-93 276.0 COG0225@1|root,COG0225@2|Bacteria,1V1MJ@1239|Firmicutes,4HG4U@91061|Bacilli,1ZRBW@1386|Bacillus 91061|Bacilli O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine msrA - 1.8.4.11 ko:K07304 - - - - ko00000,ko01000 - - - PMSR k141_32328_1 326423.RBAM_002880 5.95e-145 414.0 COG0346@1|root,COG0346@2|Bacteria,1TQCN@1239|Firmicutes,4HAMC@91061|Bacilli,1ZAQY@1386|Bacillus 91061|Bacilli E COG0346 Lactoylglutathione lyase and related lyases ydfO - - ko:K15975 - - - - ko00000 - - - Glyoxalase k141_32328_2 1174504.AJTN02000057_gene3924 1.03e-48 157.0 COG2259@1|root,COG2259@2|Bacteria,1V7TX@1239|Firmicutes,4HJ1T@91061|Bacilli,1ZGHR@1386|Bacillus 91061|Bacilli S DoxX ydfP - - ko:K15977 - - - - ko00000 - - - DoxX k141_12300_1 42565.FP66_03460 1.99e-165 467.0 COG1638@1|root,COG1638@2|Bacteria,1PER4@1224|Proteobacteria,1RPPJ@1236|Gammaproteobacteria,1XIJ9@135619|Oceanospirillales 135619|Oceanospirillales G C4-dicarboxylate ABC transporter - - - - - - - - - - - - DctP k141_13453_2 1279017.AQYJ01000029_gene3598 4.01e-104 302.0 COG1522@1|root,COG1522@2|Bacteria,1RFG8@1224|Proteobacteria,1T01M@1236|Gammaproteobacteria,46CZZ@72275|Alteromonadaceae 1236|Gammaproteobacteria K helix_turn_helix ASNC type - - - ko:K03719 - - - - ko00000,ko03000,ko03036 - - - AsnC_trans_reg,HTH_24 k141_13453_3 1453501.JELR01000001_gene2135 3.89e-151 432.0 COG0697@1|root,COG0697@2|Bacteria,1QSKQ@1224|Proteobacteria,1RYG1@1236|Gammaproteobacteria,466BE@72275|Alteromonadaceae 1236|Gammaproteobacteria EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - ko:K07052 - - - - ko00000 - - - EamA k141_35932_1 218284.CCDN010000001_gene713 1.1e-128 373.0 COG1161@1|root,COG1161@2|Bacteria,1TPM2@1239|Firmicutes,4HAAF@91061|Bacilli,1ZBES@1386|Bacillus 91061|Bacilli S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis yqeH GO:0003674,GO:0003824,GO:0003924,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019219,GO:0019222,GO:0022613,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0042254,GO:0044085,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0071840,GO:0080090,GO:0090329,GO:2000104,GO:2000112,GO:2000113 - ko:K06948 - - - - ko00000,ko03009 - - - MMR_HSR1 k141_8642_2 218284.CCDN010000001_gene1897 4.35e-70 218.0 COG4589@1|root,COG4589@2|Bacteria,1TT0Q@1239|Firmicutes,4HAMN@91061|Bacilli,1ZBWF@1386|Bacillus 91061|Bacilli S Belongs to the CDS family cdsA GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS06255 CTP_transf_1 k141_5065_2 1042377.AFPJ01000009_gene215 2.11e-33 125.0 COG2265@1|root,COG2265@2|Bacteria,1MY45@1224|Proteobacteria,1RN2B@1236|Gammaproteobacteria,4645S@72275|Alteromonadaceae 1236|Gammaproteobacteria J Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA) trmA GO:0000049,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016740,GO:0016741,GO:0019843,GO:0030488,GO:0030696,GO:0030697,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363 2.1.1.35 ko:K00557 - - - - ko00000,ko01000,ko03016 - - - tRNA_U5-meth_tr k141_26642_1 518766.Rmar_1115 3.12e-08 55.8 COG2008@1|root,COG2008@2|Bacteria,4NEIH@976|Bacteroidetes,1FIQX@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes E Beta-eliminating lyase - - 4.1.2.48 ko:K01620 ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230 - R00751,R06171 RC00312,RC00372 ko00000,ko00001,ko01000 - - - Beta_elim_lyase k141_26642_2 218284.CCDN010000001_gene1397 1.72e-33 119.0 28P1F@1|root,2ZBXS@2|Bacteria,1V1PR@1239|Firmicutes,4IAIX@91061|Bacilli,1ZIVA@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2680) yckD - - - - - - - - - - - DUF2680 k141_8643_1 218284.CCDN010000009_gene4312 1.59e-69 220.0 COG3595@1|root,COG3595@2|Bacteria,1V94C@1239|Firmicutes,4HJYP@91061|Bacilli,1ZEE4@1386|Bacillus 91061|Bacilli S Putative adhesin liaG - - ko:K11621 ko02020,map02020 - - - ko00000,ko00001 - - - DUF4097 k141_12301_1 935836.JAEL01000082_gene1042 1.73e-46 150.0 arCOG03655@1|root,32S6W@2|Bacteria,1VCVG@1239|Firmicutes,4HKHA@91061|Bacilli,1ZIIH@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_19318_1 1453501.JELR01000001_gene1932 1.98e-185 515.0 COG0024@1|root,COG0024@2|Bacteria,1MU99@1224|Proteobacteria,1RMHN@1236|Gammaproteobacteria,46498@72275|Alteromonadaceae 1236|Gammaproteobacteria E Methionine aminopeptidase map - 3.4.11.18 ko:K01265 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M24 k141_34782_1 1082933.MEA186_04556 8.31e-21 96.7 COG2911@1|root,COG3204@1|root,COG2911@2|Bacteria,COG3204@2|Bacteria 2|Bacteria L pilus organization - - - ko:K02674,ko:K07004 - - - - ko00000,ko02035,ko02044 - - - Cadherin,Exo_endo_phos,HemolysinCabind,LTD,Laminin_G_3,SNase k141_8644_1 666685.R2APBS1_3607 2e-13 65.5 COG2827@1|root,COG2827@2|Bacteria,1MZME@1224|Proteobacteria,1S8Z1@1236|Gammaproteobacteria,1X8PD@135614|Xanthomonadales 135614|Xanthomonadales L endonuclease containing a URI domain - - - ko:K07461 - - - - ko00000 - - - GIY-YIG k141_18217_1 1279017.AQYJ01000026_gene288 3.38e-87 265.0 COG3073@1|root,COG3073@2|Bacteria,1N9FN@1224|Proteobacteria,1SCNH@1236|Gammaproteobacteria,46CT4@72275|Alteromonadaceae 1236|Gammaproteobacteria T Anti sigma-E protein RseA, N-terminal domain algS - - ko:K03597 - - - - ko00000,ko03021 - - - RseA_C,RseA_N k141_13482_1 1449355.JQNR01000005_gene3591 2.17e-14 76.3 COG0839@1|root,COG0839@2|Bacteria,2GKRS@201174|Actinobacteria 201174|Actinobacteria C Belongs to the complex I subunit 6 family nuoJ - 1.6.5.3 ko:K00339 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q3 k141_21742_1 218284.CCDN010000009_gene4272 4.93e-111 320.0 COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,4HC17@91061|Bacilli,1ZCZ4@1386|Bacillus 91061|Bacilli K Belongs to the sigma-70 factor family. ECF subfamily sigW - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_21742_2 218284.CCDN010000009_gene4273 1.36e-33 120.0 COG1664@1|root,COG1664@2|Bacteria,1UIJB@1239|Firmicutes,4ISJY@91061|Bacilli 91061|Bacilli M Putative zinc-finger - - - - - - - - - - - - Bactofilin,zf-HC2 k141_22973_1 42565.FP66_00050 3.6e-117 347.0 COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,1RMY0@1236|Gammaproteobacteria,1XH8A@135619|Oceanospirillales 135619|Oceanospirillales K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released rpoN - - ko:K03092 ko02020,ko05111,map02020,map05111 - - - ko00000,ko00001,ko03021 - - - Sigma54_AID,Sigma54_CBD,Sigma54_DBD k141_16981_1 1219076.N646_0407 2.9e-39 137.0 COG0388@1|root,COG0388@2|Bacteria,1MXG5@1224|Proteobacteria,1RP7S@1236|Gammaproteobacteria,1XSG7@135623|Vibrionales 135623|Vibrionales S Carbon-nitrogen hydrolase - - 3.5.1.53 ko:K12251 ko00330,ko01100,map00330,map01100 - R01152 RC00096 ko00000,ko00001,ko01000 - - - CN_hydrolase k141_16981_2 1116375.VEJY3_08280 6.82e-310 844.0 COG0665@1|root,COG0665@2|Bacteria,1MVGP@1224|Proteobacteria,1RNJ9@1236|Gammaproteobacteria,1XSCR@135623|Vibrionales 135623|Vibrionales E COG0665 Glycine D-amino acid oxidases (deaminating) - - - ko:K09471 ko00330,ko01100,map00330,map01100 M00136 R07415 RC00062 ko00000,ko00001,ko00002,ko01000 - - - DAO k141_16981_3 1116375.VEJY3_08285 0.0 969.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,1XSW9@135623|Vibrionales 135623|Vibrionales C Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid - - 1.2.1.3,1.2.1.99 ko:K00128,ko:K09472 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135,M00136 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R07417,R07418,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_16981_4 1116375.VEJY3_08290 1.88e-123 352.0 COG1396@1|root,COG1917@1|root,COG1396@2|Bacteria,COG1917@2|Bacteria,1RCYA@1224|Proteobacteria,1S4B9@1236|Gammaproteobacteria,1XV0X@135623|Vibrionales 135623|Vibrionales K Cro/C1-type HTH DNA-binding domain - - - ko:K14056 - - - - ko00000,ko03000 - - - Cupin_2,HTH_3 k141_16981_5 1116375.VEJY3_08295 3.03e-176 491.0 COG2071@1|root,COG2071@2|Bacteria,1MV8E@1224|Proteobacteria,1RS51@1236|Gammaproteobacteria,1XV60@135623|Vibrionales 135623|Vibrionales S Peptidase C26 - - - ko:K07010 - - - - ko00000,ko01002 - - - Peptidase_C26 k141_16981_6 1116375.VEJY3_08300 1.69e-312 852.0 COG0174@1|root,COG0174@2|Bacteria,1MU6V@1224|Proteobacteria,1RPNZ@1236|Gammaproteobacteria,1XVID@135623|Vibrionales 135623|Vibrionales E glutamine synthetase - - 6.3.1.11 ko:K09470 ko00330,ko01100,map00330,map01100 M00136 R07414 RC00090,RC00096 ko00000,ko00001,ko00002,ko01000 - - - Gln-synt_C k141_16981_7 1116375.VEJY3_08305 0.0 904.0 COG1757@1|root,COG1757@2|Bacteria,1MY5C@1224|Proteobacteria,1RP6I@1236|Gammaproteobacteria,1XVHN@135623|Vibrionales 135623|Vibrionales C Na+/H+ antiporter family - - - - - - - - - - - - Na_H_antiporter k141_16981_9 866536.Belba_0242 1.2e-13 80.1 COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,47MTM@768503|Cytophagia 976|Bacteroidetes MU Belongs to the ompA family - - - - - - - - - - - - OmpA,PD40,TPR_16,TPR_2,TPR_8 k141_16981_11 7213.XP_004532830.1 4.79e-176 536.0 2D1GX@1|root,2SI2X@2759|Eukaryota,3AIB7@33154|Opisthokonta,3BZ5T@33208|Metazoa,3DEMZ@33213|Bilateria,427XH@6656|Arthropoda,3SR3U@50557|Insecta 33208|Metazoa S outer membrane usher protein - - - - - - - - - - - - PapC_C,Usher k141_16981_12 745277.GRAQ_02798 1.25e-50 172.0 COG3121@1|root,COG3121@2|Bacteria,1Q6I1@1224|Proteobacteria,1S1FJ@1236|Gammaproteobacteria,3FG5Y@34037|Rahnella 1236|Gammaproteobacteria NU Pili assembly chaperone PapD, C-terminal domain - - - ko:K07346 - - - - ko00000,ko02035,ko02044,ko03110 - - - PapD_C,PapD_N k141_16981_13 712898.Pvag_3602 4.35e-06 51.6 COG3539@1|root,COG3539@2|Bacteria,1Q00X@1224|Proteobacteria,1SPQ7@1236|Gammaproteobacteria,3W1G6@53335|Pantoea 1236|Gammaproteobacteria NU Fimbrial protein - - - ko:K07345 ko05133,map05133 - - - ko00000,ko00001,ko02035,ko02044 - - - Fimbrial k141_20477_2 218284.CCDN010000001_gene1855 3.8e-241 674.0 COG1418@1|root,COG1418@2|Bacteria,1TP48@1239|Firmicutes,4HC9J@91061|Bacilli,1ZBGP@1386|Bacillus 91061|Bacilli S Endoribonuclease that initiates mRNA decay rny GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K18682 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - DUF3552,HD,KH_1 k141_7572_1 1294265.JCM21738_112 4.64e-79 241.0 COG0142@1|root,COG0142@2|Bacteria,1V1TG@1239|Firmicutes,4HIBX@91061|Bacilli,1ZETD@1386|Bacillus 91061|Bacilli H heptaprenyl diphosphate synthase hepS - 2.5.1.30 ko:K00805 ko00900,ko01110,map00900,map01110 - R09247 RC00279 ko00000,ko00001,ko01000,ko01006 - - - HEPPP_synt_1 k141_8872_1 1123284.KB899044_gene505 2.32e-11 62.4 COG4502@1|root,COG4502@2|Bacteria,1V87A@1239|Firmicutes,4HJ5I@91061|Bacilli 91061|Bacilli S 5'(3')-deoxyribonucleotidase - - - - - - - - - - - - NT5C k141_8872_2 717606.PaecuDRAFT_0826 3.49e-34 122.0 COG4502@1|root,COG4502@2|Bacteria,1V87A@1239|Firmicutes,4HJ5I@91061|Bacilli 91061|Bacilli S 5'(3')-deoxyribonucleotidase - - - - - - - - - - - - NT5C k141_5290_1 1215092.PA6_008_00930 1.1e-33 124.0 COG0744@1|root,COG0744@2|Bacteria,1RDAQ@1224|Proteobacteria,1RMGB@1236|Gammaproteobacteria,1YCVN@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria M Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors mtgA GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008955,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0030203,GO:0034645,GO:0042546,GO:0043164,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.4.1.129 ko:K03814 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly k141_21882_1 1294265.JCM21738_5066 2.97e-08 51.2 COG2151@1|root,COG2151@2|Bacteria,1V9YV@1239|Firmicutes,4HKC6@91061|Bacilli,1ZH2A@1386|Bacillus 91061|Bacilli S metal-sulfur cluster biosynthetic enzyme yitW - - - - - - - - - - - FeS_assembly_P k141_21882_2 1294265.JCM21738_5065 1.79e-112 327.0 COG1073@1|root,COG1073@2|Bacteria,1TTC0@1239|Firmicutes,4HBCG@91061|Bacilli,1ZBIJ@1386|Bacillus 91061|Bacilli S COG1073 Hydrolases of the alpha beta superfamily yitV - - ko:K06889 - - - - ko00000 - - - Abhydrolase_1,Hydrolase_4,Peptidase_S9 k141_10075_1 218284.CCDN010000002_gene2003 1.07e-192 541.0 COG2224@1|root,COG2224@2|Bacteria,1TP1U@1239|Firmicutes,4HBBD@91061|Bacilli,1ZBPW@1386|Bacillus 91061|Bacilli C Isocitrate lyase aceA - 4.1.3.1 ko:K01637 ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200 M00012 R00479 RC00311,RC00313 ko00000,ko00001,ko00002,ko01000 - - - ICL k141_1606_2 675817.VDA_001296 8.69e-92 304.0 2CDZY@1|root,31BX8@2|Bacteria,1RI0W@1224|Proteobacteria,1SE4J@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_1606_4 1116375.VEJY3_13155 1.19e-100 292.0 COG2137@1|root,COG2137@2|Bacteria,1N6P6@1224|Proteobacteria,1SCMF@1236|Gammaproteobacteria,1XWKA@135623|Vibrionales 135623|Vibrionales S Modulates RecA activity recX GO:0006282,GO:0008150,GO:0019219,GO:0019222,GO:0031323,GO:0048583,GO:0050789,GO:0050794,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0080090,GO:0080134,GO:0080135,GO:2001020 - ko:K03565 - - - - ko00000,ko03400 - - - RecX k141_1606_5 223926.28807546 0.0 1621.0 COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,1RMWZ@1236|Gammaproteobacteria,1XUIK@135623|Vibrionales 135623|Vibrionales J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain alaS GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DHHA1,tRNA-synt_2c,tRNA_SAD k141_1606_6 1116375.VEJY3_13145 1.69e-250 691.0 COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,1RN1G@1236|Gammaproteobacteria,1XU5V@135623|Vibrionales 135623|Vibrionales E Belongs to the aspartokinase family lysC - 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase k141_1606_7 55601.VANGNB10_cI0452 1.29e-35 121.0 COG1551@1|root,COG1551@2|Bacteria,1N6PG@1224|Proteobacteria,1SCB4@1236|Gammaproteobacteria,1XYEQ@135623|Vibrionales 135623|Vibrionales J Could accelerate the degradation of some genes transcripts potentially through selective RNA binding csrA GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0006109,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016071,GO:0019222,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0050789,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 - - - ko00000,ko00001,ko03019 - - - CsrA k141_24188_1 644801.Psest_3370 6e-21 89.4 COG4970@1|root,COG4970@2|Bacteria,1QDR3@1224|Proteobacteria,1T9UE@1236|Gammaproteobacteria,1Z3KK@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria NU Type II transport protein GspH - - - ko:K08084 - - - - ko00000,ko02044 3.A.15.2 - - GspH,N_methyl k141_24188_2 1453501.JELR01000005_gene1777 3.16e-05 50.1 COG4970@1|root,COG4970@2|Bacteria,1N7RS@1224|Proteobacteria,1SCFB@1236|Gammaproteobacteria,468CM@72275|Alteromonadaceae 1236|Gammaproteobacteria NU Type II transport protein GspH fimT - - ko:K08084 - - - - ko00000,ko02044 3.A.15.2 - - GspH,N_methyl k141_24188_3 1279017.AQYJ01000019_gene1505 4.63e-187 524.0 COG0761@1|root,COG0761@2|Bacteria,1MU7G@1224|Proteobacteria,1RMN8@1236|Gammaproteobacteria,465MC@72275|Alteromonadaceae 1236|Gammaproteobacteria IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis ispH GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0042380,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046490,GO:0048037,GO:0051536,GO:0051538,GO:0051540,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.4 ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05884,R08210 RC01137,RC01487 ko00000,ko00001,ko00002,ko01000 - - iECIAI1_1343.ECIAI1_0030,iECW_1372.ECW_m0028,iEKO11_1354.EKO11_3884,iEcHS_1320.EcHS_A0031,iEcolC_1368.EcolC_3626,iPC815.YPO0477,iSFV_1184.SFV_0023,iSF_1195.SF0026,iSFxv_1172.SFxv_0027,iS_1188.S0028,iWFL_1372.ECW_m0028,iYL1228.KPN_00024 LYTB k141_24188_4 1279017.AQYJ01000019_gene1504 6.48e-87 257.0 COG1047@1|root,COG1047@2|Bacteria,1RHD1@1224|Proteobacteria,1S5YP@1236|Gammaproteobacteria,467DE@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG1047 FKBP-type peptidyl-prolyl cis-trans isomerases 2 fkpB GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0061077,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 ko:K03774 - - - - ko00000,ko01000,ko03110 - - - FKBP_C k141_2831_2 566466.NOR53_2067 6.79e-52 177.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,1J8Y5@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Aldehyde dehydrogenase family - - 1.2.1.3,1.2.1.71,1.2.1.9 ko:K00128,ko:K00131,ko:K06447 ko00010,ko00030,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130,map01200 M00135,M00308,M00633 R00264,R00631,R00710,R00904,R01058,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05049,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_26878_1 1453501.JELR01000002_gene178 9.97e-63 212.0 COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,1RQIX@1236|Gammaproteobacteria,4669Y@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0457 FOG TPR repeat - - - - - - - - - - - - TPR_14,TPR_16,TPR_19,TPR_2,TPR_6,TPR_8 k141_11272_1 1414737.V9QJI4_9CAUD 9.83e-22 94.7 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - GO:0005575,GO:0019012,GO:0019028,GO:0032991,GO:0044423,GO:0046806 - - - - - - - - - - - k141_37274_1 1196031.ALEG01000028_gene4112 5.99e-72 217.0 COG2363@1|root,COG2363@2|Bacteria,1VA79@1239|Firmicutes,4HKHG@91061|Bacilli,1ZGYJ@1386|Bacillus 91061|Bacilli S small membrane protein ywdK - - - - - - - - - - - DUF423 k141_37274_2 1294265.JCM21738_1771 9.44e-47 152.0 2DRJS@1|root,33C32@2|Bacteria,1VPJY@1239|Firmicutes,4HRSY@91061|Bacilli,1ZHI1@1386|Bacillus 91061|Bacilli S Family of unknown function (DUF5327) ywdI - - - - - - - - - - - DUF5327 k141_27700_1 1453501.JELR01000002_gene164 6.86e-135 383.0 COG2259@1|root,COG2259@2|Bacteria,1RBZP@1224|Proteobacteria,1S28E@1236|Gammaproteobacteria,466DA@72275|Alteromonadaceae 1236|Gammaproteobacteria S DoxX - - - ko:K15977 - - - - ko00000 - - - DoxX k141_10112_1 218284.CCDN010000005_gene3362 2.77e-48 159.0 2EA57@1|root,334A4@2|Bacteria,1VHEA@1239|Firmicutes,4HQU5@91061|Bacilli,1ZRA3@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_13727_1 1317118.ATO8_16390 7.29e-70 221.0 COG1638@1|root,COG1638@2|Bacteria,1MWAM@1224|Proteobacteria,2TTT8@28211|Alphaproteobacteria,4KP1I@93682|Roseivivax 28211|Alphaproteobacteria G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component - - - - - - - - - - - - DctP k141_8902_1 715451.ambt_12090 2.94e-40 147.0 COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,1RMCY@1236|Gammaproteobacteria,464D7@72275|Alteromonadaceae 1236|Gammaproteobacteria U Involved in the TonB-independent uptake of proteins tolB GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015031,GO:0015833,GO:0015893,GO:0017038,GO:0019904,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0032991,GO:0033036,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0043213,GO:0044464,GO:0044877,GO:0045184,GO:0046677,GO:0046678,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0070887,GO:0071236,GO:0071237,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701 - ko:K03641 - - - - ko00000,ko02000 2.C.1.2 - - PD40,TolB_N k141_24235_1 1347369.CCAD010000056_gene4350 8.98e-46 152.0 COG1595@1|root,COG1595@2|Bacteria,1V7EE@1239|Firmicutes,4HIXE@91061|Bacilli,1ZEMR@1386|Bacillus 91061|Bacilli K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_23204_3 218284.CCDN010000002_gene2929 2.34e-215 597.0 COG1988@1|root,COG1988@2|Bacteria,1TQFC@1239|Firmicutes,4H9PU@91061|Bacilli,1ZBEI@1386|Bacillus 91061|Bacilli S membrane-bound metal-dependent yfhP - - ko:K07038 - - - - ko00000 - - - YdjM k141_15927_2 997346.HMPREF9374_0298 1.02e-13 72.8 COG1570@1|root,COG1570@2|Bacteria,1TP4E@1239|Firmicutes,4HAN2@91061|Bacilli,27B9K@186824|Thermoactinomycetaceae 91061|Bacilli L Exonuclease VII, large subunit xseA - 3.1.11.6 ko:K03601 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_L,tRNA_anti_2 k141_24236_1 218284.CCDN010000008_gene4229 1.5e-106 333.0 COG3383@1|root,COG3383@2|Bacteria,1UHTX@1239|Firmicutes,4IPM7@91061|Bacilli,1ZRCN@1386|Bacillus 91061|Bacilli C formate dehydrogenase, alpha subunit - - 1.17.1.9 ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001,ko01000 - - - Fer2_4,Fer4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3 k141_19546_1 439496.RBY4I_1553 3.36e-118 342.0 COG0693@1|root,COG0693@2|Bacteria,1MVTT@1224|Proteobacteria,2TT0C@28211|Alphaproteobacteria 28211|Alphaproteobacteria C intracellular protease amidase - - - - - - - - - - - - DJ-1_PfpI k141_19546_2 1535422.ND16A_3648 2.77e-30 117.0 COG1446@1|root,COG1446@2|Bacteria,1MWFC@1224|Proteobacteria,1RNUR@1236|Gammaproteobacteria,2Q6GA@267889|Colwelliaceae 1236|Gammaproteobacteria E Asparaginase iaaA - 3.4.19.5,3.5.1.1 ko:K01424,ko:K13051 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 - R00485 RC00010,RC02798 ko00000,ko00001,ko01000,ko01002 - - - Asparaginase_2 k141_10113_1 218284.CCDN010000005_gene3468 1.09e-139 407.0 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli,1ZAY9@1386|Bacillus 91061|Bacilli C Belongs to the aldehyde dehydrogenase family acoD - - ko:K00138 ko00010,ko00620,ko01100,ko01110,ko01120,map00010,map00620,map01100,map01110,map01120 - R00711 RC00047 ko00000,ko00001,ko01000 - - - Aldedh k141_652_2 1453501.JELR01000001_gene2198 1.34e-186 551.0 COG1330@1|root,COG2887@1|root,COG1330@2|Bacteria,COG2887@2|Bacteria,1QVX1@1224|Proteobacteria,1RP9I@1236|Gammaproteobacteria,465DQ@72275|Alteromonadaceae 1236|Gammaproteobacteria L PD-(D/E)XK nuclease superfamily lidB - - - - - - - - - - - PDDEXK_1 k141_23205_1 218284.CCDN010000001_gene177 2.01e-25 102.0 COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,4H9SG@91061|Bacilli,1ZC15@1386|Bacillus 91061|Bacilli E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate hipO GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0050118,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.1.47 ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 M00525 R02733 RC00064,RC00300 ko00000,ko00001,ko00002,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 k141_23205_2 406124.ACPC01000009_gene1565 1.72e-38 135.0 COG2171@1|root,COG2171@2|Bacteria,1TQUJ@1239|Firmicutes,4H9KY@91061|Bacilli,1ZBFG@1386|Bacillus 91061|Bacilli E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate dapH - 2.3.1.117,2.3.1.89 ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 M00016,M00525 R04364,R04365 RC00004,RC01136 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU14180 DapH_N,Hexapep k141_14695_1 218284.CCDN010000005_gene3221 3.57e-116 336.0 COG0398@1|root,COG0398@2|Bacteria,1TS5T@1239|Firmicutes,4HDKU@91061|Bacilli,1ZCHZ@1386|Bacillus 91061|Bacilli S SNARE associated Golgi protein yhjE - - - - - - - - - - - SNARE_assoc k141_20668_1 223926.28808415 0.0 903.0 COG0025@1|root,COG1226@1|root,COG0025@2|Bacteria,COG1226@2|Bacteria,1QTUE@1224|Proteobacteria,1T1HJ@1236|Gammaproteobacteria,1XUJX@135623|Vibrionales 135623|Vibrionales P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family - - - - - - - - - - - - Na_H_Exchanger,TrkA_N k141_20668_2 223926.28808398 1.21e-102 305.0 COG0741@1|root,COG0741@2|Bacteria,1N30Z@1224|Proteobacteria,1SA9P@1236|Gammaproteobacteria,1XWHM@135623|Vibrionales 135623|Vibrionales M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - - - - - - - - - - SLT k141_20668_3 223926.28808396 1.06e-120 347.0 COG1051@1|root,COG1051@2|Bacteria,1RB8R@1224|Proteobacteria,1S1A6@1236|Gammaproteobacteria,1XSJ6@135623|Vibrionales 135623|Vibrionales F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - - - - - - - - - - NUDIX k141_20668_4 1280001.BAOA01000050_gene1439 5.91e-31 110.0 COG3042@1|root,COG3042@2|Bacteria,1N8JF@1224|Proteobacteria,1SCRE@1236|Gammaproteobacteria,1XYGI@135623|Vibrionales 135623|Vibrionales S Hemolysin - - - ko:K09712 - - - - ko00000 - - - DUF333 k141_20668_5 1116375.VEJY3_16626 2.31e-132 378.0 2E047@1|root,32VSV@2|Bacteria,1RK11@1224|Proteobacteria,1S49N@1236|Gammaproteobacteria,1XXG7@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_20668_6 1116375.VEJY3_16621 1.1e-121 356.0 COG1434@1|root,COG1434@2|Bacteria,1QJMZ@1224|Proteobacteria,1THNK@1236|Gammaproteobacteria,1XWXP@135623|Vibrionales 135623|Vibrionales S DUF218 domain - - - - - - - - - - - - DUF218 k141_20668_7 1116375.VEJY3_16616 0.0 870.0 COG1760@1|root,COG1760@2|Bacteria,1MUZN@1224|Proteobacteria,1RMJZ@1236|Gammaproteobacteria,1XSZW@135623|Vibrionales 135623|Vibrionales E COG1760 L-serine deaminase - - 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 - R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 - - - SDH_alpha,SDH_beta k141_20668_8 1116375.VEJY3_16611 1.24e-168 475.0 COG0583@1|root,COG0583@2|Bacteria,1R6N4@1224|Proteobacteria,1RS69@1236|Gammaproteobacteria,1XV52@135623|Vibrionales 135623|Vibrionales K Bacterial regulatory helix-turn-helix protein, lysR family - - - ko:K03566 ko02026,map02026 - - - ko00000,ko00001,ko03000 - - - HTH_1,LysR_substrate k141_20668_9 223926.28808384 3.68e-274 750.0 COG2866@1|root,COG2866@2|Bacteria,1MUMN@1224|Proteobacteria,1RQB4@1236|Gammaproteobacteria,1XU40@135623|Vibrionales 135623|Vibrionales E Zn_pept - - - - - - - - - - - - Peptidase_M14 k141_20668_10 1116375.VEJY3_16596 3.21e-15 74.3 COG0665@1|root,COG0665@2|Bacteria,1MVGP@1224|Proteobacteria,1RNJ9@1236|Gammaproteobacteria,1XSCR@135623|Vibrionales 135623|Vibrionales E COG0665 Glycine D-amino acid oxidases (deaminating) - - - - - - - - - - - - DAO k141_35006_1 1238450.VIBNISOn1_800024 7.87e-07 52.8 2DIF1@1|root,3031J@2|Bacteria,1QPZ0@1224|Proteobacteria,1SJT0@1236|Gammaproteobacteria 1236|Gammaproteobacteria S RES - - - - - - - - - - - - RES k141_13729_1 1117314.PCIT_05759 1.52e-16 81.6 COG0582@1|root,COG0582@2|Bacteria,1R5TQ@1224|Proteobacteria,1RY85@1236|Gammaproteobacteria,2Q4HG@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria L Phage integrase family - - - - - - - - - - - - Phage_integrase k141_15928_1 351016.RAZWK3B_01270 1.09e-34 127.0 COG1910@1|root,COG1910@2|Bacteria,1MVS4@1224|Proteobacteria,2TU96@28211|Alphaproteobacteria 28211|Alphaproteobacteria P COG1910, Periplasmic molybdate-binding protein domain - - - - - - - - - - - - HTH_17,PBP_like k141_25551_1 42565.FP66_07125 6.66e-104 320.0 COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,1RPZ7@1236|Gammaproteobacteria,1XHF9@135619|Oceanospirillales 135619|Oceanospirillales L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA priA - - ko:K04066 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,ResIII k141_10114_1 1294265.JCM21738_1035 8.6e-118 343.0 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli,1ZAXK@1386|Bacillus 91061|Bacilli C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively - - - - - - - - - - - - Aldedh k141_24237_2 935837.JAEK01000018_gene854 3.26e-34 117.0 COG0291@1|root,COG0291@2|Bacteria,1VF5W@1239|Firmicutes,4HNIQ@91061|Bacilli,1ZJBX@1386|Bacillus 91061|Bacilli J Belongs to the bacterial ribosomal protein bL35 family rpmI GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02916 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L35p k141_5330_2 1415778.JQMM01000001_gene478 1.5e-45 156.0 COG3124@1|root,COG3124@2|Bacteria,1MZ59@1224|Proteobacteria,1S9IZ@1236|Gammaproteobacteria,1J6R8@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria acpH GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008081,GO:0008150,GO:0008152,GO:0008610,GO:0008770,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0016788,GO:0019752,GO:0032787,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:0140096,GO:1901576 3.1.4.14 ko:K08682 ko00770,map00770 - R01623 - ko00000,ko00001,ko01000 - - iAPECO1_1312.APECO1_1606,iE2348C_1286.E2348C_0339,iECNA114_1301.ECNA114_0381,iECOK1_1307.ECOK1_0384,iECS88_1305.ECS88_0399,iECSF_1327.ECSF_0364,iPC815.YPO3193,iUMN146_1321.UM146_15340,iUTI89_1310.UTI89_C0426 ACP_PD k141_5330_4 1279017.AQYJ01000027_gene1924 6.92e-44 147.0 2EB97@1|root,3359Q@2|Bacteria,1NBYB@1224|Proteobacteria,1SDC9@1236|Gammaproteobacteria,468XQ@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_25552_1 314278.NB231_08132 3.78e-92 300.0 COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,1RMK0@1236|Gammaproteobacteria,1WX4P@135613|Chromatiales 135613|Chromatiales K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoB - 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 k141_35007_1 1453501.JELR01000001_gene2240 1.09e-47 155.0 COG4633@1|root,COG4633@2|Bacteria,1N1UQ@1224|Proteobacteria,1S9HX@1236|Gammaproteobacteria,467WZ@72275|Alteromonadaceae 1236|Gammaproteobacteria S Cupredoxin-like domain - - - - - - - - - - - - Cupredoxin_1 k141_8903_1 218284.CCDN010000001_gene1506 1.24e-247 702.0 COG1048@1|root,COG1048@2|Bacteria,1VTMM@1239|Firmicutes,4HB5N@91061|Bacilli,1ZART@1386|Bacillus 91061|Bacilli C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate citB GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0043937,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0050789,GO:0050793,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0065007,GO:0071704,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_C k141_11273_1 1219076.N646_0216 4.53e-205 569.0 COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,1RMEI@1236|Gammaproteobacteria,1XT4Q@135623|Vibrionales 135623|Vibrionales P Belongs to the ABC transporter superfamily sapD - - ko:K19229 ko01503,ko02010,map01503,map02010 M00739 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.5 - - ABC_tran,oligo_HPY k141_11273_2 1116375.VEJY3_05700 8.07e-184 514.0 COG4171@1|root,COG4171@2|Bacteria,1QUAT@1224|Proteobacteria,1T1RQ@1236|Gammaproteobacteria,1XSV7@135623|Vibrionales 135623|Vibrionales V COG4171 ABC-type antimicrobial peptide transport system, permease component sapC - - ko:K19228 ko01503,ko02010,map01503,map02010 M00739 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.5 - - BPD_transp_1,OppC_N k141_1627_1 1403313.AXBR01000003_gene3983 1.38e-140 410.0 COG1680@1|root,COG1680@2|Bacteria,1U828@1239|Firmicutes,4HA0Q@91061|Bacilli,1ZBJ0@1386|Bacillus 91061|Bacilli V Belongs to the UPF0214 family ybbE - 3.4.16.4 ko:K21469 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - Beta-lactamase k141_1627_2 1453501.JELR01000002_gene1499 2.62e-68 209.0 COG1017@1|root,COG1017@2|Bacteria,1RI9P@1224|Proteobacteria,1S7H7@1236|Gammaproteobacteria,46B0Z@72275|Alteromonadaceae 1236|Gammaproteobacteria C nitric oxide dioxygenase activity - - - - - - - - - - - - - k141_24238_1 218284.CCDN010000006_gene3573 4.62e-116 345.0 COG3486@1|root,COG3486@2|Bacteria,1UZAQ@1239|Firmicutes,4HBWJ@91061|Bacilli,1ZB3E@1386|Bacillus 91061|Bacilli Q L-lysine 6-monooxygenase (NADPH-requiring) - - 1.14.13.59 ko:K03897 ko00310,ko01120,map00310,map01120 - R00448 RC00298 ko00000,ko00001,ko01000 - - - K_oxygenase k141_32476_1 218284.CCDN010000004_gene3028 1.24e-57 180.0 COG1366@1|root,COG1366@2|Bacteria,1VER8@1239|Firmicutes,4HP2I@91061|Bacilli,1ZIDN@1386|Bacillus 91061|Bacilli T Belongs to the anti-sigma-factor antagonist family rsbV - - ko:K04749 - - - - ko00000,ko03021 - - - STAS,STAS_2 k141_13731_1 1294265.JCM21738_4463 7.83e-160 458.0 COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,4H9XC@91061|Bacilli,1ZB9E@1386|Bacillus 91061|Bacilli J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain alaS GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DHHA1,tRNA-synt_2c,tRNA_SAD k141_4140_1 1112212.JH584235_gene788 1.29e-94 312.0 COG0457@1|root,COG0457@2|Bacteria,1N06S@1224|Proteobacteria,2TQVV@28211|Alphaproteobacteria,2K2KZ@204457|Sphingomonadales 204457|Sphingomonadales S MTH538 TIR-like domain (DUF1863) - - - - - - - - - - - - DUF1863 k141_25554_1 935836.JAEL01000022_gene1633 3.26e-94 285.0 COG1914@1|root,COG1914@2|Bacteria,1TP0Q@1239|Firmicutes,4HAYE@91061|Bacilli,1ZC68@1386|Bacillus 91061|Bacilli P COG1914 Mn2 and Fe2 transporters of the NRAMP family ycsG - - - - - - - - - - - Nramp k141_7575_3 1116375.VEJY3_20216 0.0 1838.0 COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,1RND3@1236|Gammaproteobacteria,1XU09@135623|Vibrionales 135623|Vibrionales E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor gcvP - 1.4.4.2 ko:K00281 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko00002,ko01000 - - - GDC-P k141_7575_4 945543.VIBR0546_03780 2.07e-78 234.0 COG0509@1|root,COG0509@2|Bacteria,1RGV7@1224|Proteobacteria,1S656@1236|Gammaproteobacteria,1XXG5@135623|Vibrionales 135623|Vibrionales E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein gcvH GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564 - ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 - - - GCV_H k141_7575_5 1116375.VEJY3_20206 1.89e-310 846.0 COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,1S0NZ@1236|Gammaproteobacteria,1XUY2@135623|Vibrionales 135623|Vibrionales E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism glyA2 GO:0001505,GO:0003674,GO:0003824,GO:0004372,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006730,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016742,GO:0017144,GO:0019752,GO:0042133,GO:0042136,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 - - - SHMT k141_7575_6 223926.28809039 1.34e-136 387.0 COG1426@1|root,COG1426@2|Bacteria,1QUH8@1224|Proteobacteria,1RQEE@1236|Gammaproteobacteria,1XSYT@135623|Vibrionales 135623|Vibrionales K transcriptional - - - - - - - - - - - - Cupin_2,HTH_3 k141_7575_7 1116375.VEJY3_20196 1.11e-263 723.0 COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,1RN2A@1236|Gammaproteobacteria,1XSK0@135623|Vibrionales 135623|Vibrionales H COG0404 Glycine cleavage system T protein (aminomethyltransferase) gcvT - 2.1.2.10 ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 M00532 R01221,R02300,R04125 RC00022,RC00069,RC00183,RC02834 ko00000,ko00001,ko00002,ko01000 - - - GCV_T,GCV_T_C k141_7575_8 1116375.VEJY3_20191 2.51e-151 427.0 COG1309@1|root,COG1309@2|Bacteria,1QV5P@1224|Proteobacteria,1SA6I@1236|Gammaproteobacteria,1XV64@135623|Vibrionales 135623|Vibrionales K Transcriptional regulator - - - - - - - - - - - - TetR_N k141_7575_9 1219076.N646_4206 8.26e-208 580.0 COG0845@1|root,COG0845@2|Bacteria,1NJDF@1224|Proteobacteria,1SYIU@1236|Gammaproteobacteria,1Y2T0@135623|Vibrionales 135623|Vibrionales M Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - - - - - - - - - - Biotin_lipoyl_2,HlyD_3 k141_7575_10 223926.28809043 1.74e-207 579.0 COG0845@1|root,COG0845@2|Bacteria,1R4F3@1224|Proteobacteria,1RSAM@1236|Gammaproteobacteria,1XTNU@135623|Vibrionales 135623|Vibrionales M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - - - - - - - - - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 k141_7575_11 674977.VMC_21660 0.0 1818.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1XSCN@135623|Vibrionales 135623|Vibrionales V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran k141_7575_12 1280001.BAOA01000075_gene3221 1.59e-94 291.0 COG1299@1|root,COG1445@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,1MXFN@1224|Proteobacteria,1RMZC@1236|Gammaproteobacteria,1XSC5@135623|Vibrionales 135623|Vibrionales G COG1445 Phosphotransferase system fructose-specific component IIB fruA - 2.7.1.202 ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1 - - PTS_EIIC,PTS_IIB k141_20671_1 406124.ACPC01000015_gene2120 4.44e-30 110.0 COG3576@1|root,COG3576@2|Bacteria,1UJHW@1239|Firmicutes,4HWAK@91061|Bacilli,1ZHN5@1386|Bacillus 91061|Bacilli S Pyridoxamine 5'-phosphate oxidase - - - - - - - - - - - - Putative_PNPOx k141_20671_2 1196031.ALEG01000069_gene683 1.39e-50 169.0 COG0454@1|root,COG0456@2|Bacteria,1U35A@1239|Firmicutes,4HDZ3@91061|Bacilli,1ZD5S@1386|Bacillus 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_10 k141_11292_2 1116375.VEJY3_23901 9.37e-135 384.0 COG0625@1|root,COG0625@2|Bacteria,1PHM1@1224|Proteobacteria,1RMVC@1236|Gammaproteobacteria,1XVX9@135623|Vibrionales 135623|Vibrionales O Glutathione S-transferase - - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C_4,GST_N,GST_N_2,GST_N_3 k141_8913_1 1121937.AUHJ01000055_gene1198 7.02e-87 260.0 COG0500@1|root,COG2226@2|Bacteria,1R2J9@1224|Proteobacteria,1T5R2@1236|Gammaproteobacteria,46BYA@72275|Alteromonadaceae 1236|Gammaproteobacteria Q O-methyltransferase - - - - - - - - - - - - Methyltransf_2 k141_13757_1 42565.FP66_02865 7.68e-07 47.4 COG3695@1|root,COG3695@2|Bacteria,1N7J2@1224|Proteobacteria,1SCIZ@1236|Gammaproteobacteria,1XM8K@135619|Oceanospirillales 135619|Oceanospirillales L Methyltransferase - - - ko:K07443 - - - - ko00000 - - - DNA_binding_1 k141_13757_2 42565.FP66_02860 3.63e-106 309.0 COG0518@1|root,COG0518@2|Bacteria,1MUDH@1224|Proteobacteria,1RXUZ@1236|Gammaproteobacteria,1XPIB@135619|Oceanospirillales 135619|Oceanospirillales F COG0518 GMP synthase - Glutamine amidotransferase domain - - - - - - - - - - - - GATase k141_1643_1 388399.SSE37_13588 4.14e-74 230.0 COG1651@1|root,COG1651@2|Bacteria,1RFF4@1224|Proteobacteria,2U5BN@28211|Alphaproteobacteria 28211|Alphaproteobacteria O COG1651 protein-disulfide isomerase MA20_42440 - - - - - - - - - - - Thioredoxin_4 k141_19569_2 1042377.AFPJ01000053_gene1491 8.03e-315 864.0 COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,1RMY6@1236|Gammaproteobacteria,46556@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA ilvA GO:0003674,GO:0003824,GO:0004794,GO:0005488,GO:0006082,GO:0006520,GO:0006549,GO:0006566,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009081,GO:0009082,GO:0009097,GO:0009987,GO:0016053,GO:0016597,GO:0016829,GO:0016840,GO:0016841,GO:0019752,GO:0019842,GO:0030170,GO:0031406,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_2699 PALP,Thr_dehydrat_C k141_7592_1 1116375.VEJY3_11130 4.09e-196 558.0 COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,1RNYW@1236|Gammaproteobacteria,1XT9K@135623|Vibrionales 135623|Vibrionales OU signal peptide peptidase sppA - - ko:K04773 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S49 k141_4156_1 1347086.CCBA010000027_gene3531 0.000222 50.1 COG4961@1|root,COG4961@2|Bacteria,1UJS8@1239|Firmicutes,4HGJ1@91061|Bacilli,1ZSH0@1386|Bacillus 91061|Bacilli U Putative Flp pilus-assembly TadE/G-like - - - - - - - - - - - - Tad k141_32486_1 42565.FP66_14430 9.24e-122 355.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPCU@1236|Gammaproteobacteria,1XIPX@135619|Oceanospirillales 135619|Oceanospirillales S mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth - - - ko:K15738 - - - - ko00000,ko02000 3.A.1.120.6 - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn k141_11293_1 1499967.BAYZ01000095_gene4266 5.23e-82 251.0 COG1432@1|root,COG1432@2|Bacteria,2NRX6@2323|unclassified Bacteria 2|Bacteria S NYN domain - - - - - - - - - - - - CSD,NYN k141_37288_1 1042375.AFPL01000008_gene3282 2.8e-51 179.0 COG0500@1|root,COG2226@2|Bacteria,1PA5F@1224|Proteobacteria,1RY7A@1236|Gammaproteobacteria,465B1@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway bioC GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008757,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0010340,GO:0016053,GO:0016740,GO:0016741,GO:0016787,GO:0016788,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032259,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0052689,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.197 ko:K02169 ko00780,ko01100,map00780,map01100 M00572 R09543 RC00003,RC00460 ko00000,ko00001,ko00002,ko01000 - - iECP_1309.ECP_0791,iSBO_1134.SBO_0664,iSFV_1184.SFV_0760,iSF_1195.SF0727,iSFxv_1172.SFxv_0792,iSSON_1240.SSON_0756,iS_1188.S0768,iSbBS512_1146.SbBS512_E2575 Methyltransf_11 k141_18443_1 796606.BMMGA3_04480 6.28e-138 397.0 COG1744@1|root,COG1744@2|Bacteria,1UY2H@1239|Firmicutes,4HCI5@91061|Bacilli,1ZBN4@1386|Bacillus 91061|Bacilli S Transcriptional activator protein med med - - ko:K05519,ko:K07335 - - - - ko00000,ko03000 - - - Bmp k141_10339_1 1196324.A374_00300 1.87e-18 84.3 COG0640@1|root,COG0640@2|Bacteria,1TSRQ@1239|Firmicutes,4HBXM@91061|Bacilli 91061|Bacilli K arsR family transcriptional regulator - - - - - - - - - - - - HTH_20,HTH_5 k141_10339_2 1235279.C772_00904 2.93e-62 194.0 COG0346@1|root,COG0346@2|Bacteria,1V7AX@1239|Firmicutes,4HJ5Z@91061|Bacilli,26FIP@186818|Planococcaceae 91061|Bacilli E lactoylglutathione lyase activity - - - - - - - - - - - - Glyoxalase k141_10339_3 1385511.N783_10530 5.54e-21 88.2 COG0537@1|root,COG0537@2|Bacteria,1V83D@1239|Firmicutes,4HIH2@91061|Bacilli,2YANT@289201|Pontibacillus 91061|Bacilli FG Domain of unknown function (DUF4269) - - - - - - - - - - - - DUF4269 k141_30228_1 1449065.JMLL01000016_gene3024 1.39e-42 160.0 2DB7D@1|root,2Z7KR@2|Bacteria,1Q0FB@1224|Proteobacteria,2V1V2@28211|Alphaproteobacteria,43Q56@69277|Phyllobacteriaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_29139_1 997296.PB1_13884 1.58e-16 74.3 COG0853@1|root,COG0853@2|Bacteria,1V6NQ@1239|Firmicutes,4HIV1@91061|Bacilli,1ZG9V@1386|Bacillus 91061|Bacilli H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine panD - 4.1.1.11 ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 M00119 R00489 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Asp_decarbox k141_29139_2 218284.CCDN010000001_gene1141 7.98e-53 184.0 COG0847@1|root,COG1199@1|root,COG0847@2|Bacteria,COG1199@2|Bacteria,1TQHQ@1239|Firmicutes,4HB2Y@91061|Bacilli,1ZAWI@1386|Bacillus 91061|Bacilli L helicase involved in DNA repair and perhaps also replication dinG - 3.6.4.12 ko:K03722 - - - - ko00000,ko01000,ko03400 - - - DEAD,Helicase_C_2,RNase_T,ResIII k141_2960_1 218284.CCDN010000001_gene1894 9.17e-219 617.0 COG0442@1|root,COG0442@2|Bacteria,1TRBV@1239|Firmicutes,4H9NN@91061|Bacilli,1ZD7M@1386|Bacillus 91061|Bacilli J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS proS - 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_2b,tRNA_edit k141_2960_2 218284.CCDN010000001_gene1895 1.22e-205 575.0 COG0750@1|root,COG0750@2|Bacteria,1TPMC@1239|Firmicutes,4HAQ5@91061|Bacilli,1ZCPQ@1386|Bacillus 91061|Bacilli M zinc metalloprotease rasP - - ko:K11749 ko02024,ko04112,map02024,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - PDZ_2,Peptidase_M50 k141_803_1 1397699.JNIS01000001_gene3010 4.04e-70 227.0 COG0477@1|root,COG2814@2|Bacteria,1TQ5B@1239|Firmicutes,4IT16@91061|Bacilli,3WFWA@539002|Bacillales incertae sedis 91061|Bacilli EGP Transmembrane secretion effector - - - - - - - - - - - - MFS_1,MFS_3 k141_803_2 574375.BAGA_09220 5.33e-09 58.2 COG0477@1|root,COG2814@2|Bacteria,1TQ5B@1239|Firmicutes,4HCD8@91061|Bacilli,1ZBCU@1386|Bacillus 91061|Bacilli EGP Transmembrane secretion effector - - - - - - - - - - - - MFS_1 k141_33990_1 1294265.JCM21738_4208 1.4e-10 60.8 COG0614@1|root,COG0614@2|Bacteria,1TR63@1239|Firmicutes,4HB8N@91061|Bacilli,1ZCYN@1386|Bacillus 91061|Bacilli P ABC transporter substrate-binding protein yfiY - - ko:K02016 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - Peripla_BP_2 k141_33990_2 1294265.JCM21738_4209 3.12e-57 186.0 COG0609@1|root,COG0609@2|Bacteria,1TP13@1239|Firmicutes,4HAW8@91061|Bacilli,1ZQ8X@1386|Bacillus 91061|Bacilli P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily yfiZ - - ko:K02015 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - iYO844.BSU08450 FecCD k141_10340_1 218284.CCDN010000001_gene735 5.79e-133 384.0 COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,4H9KA@91061|Bacilli,1ZC0R@1386|Bacillus 91061|Bacilli O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins dnaJ - - ko:K03686 - - - - ko00000,ko03029,ko03110 - - - DnaJ,DnaJ_C,DnaJ_CXXCXGXG k141_27846_1 1437882.AZRU01000017_gene6415 1.61e-101 315.0 COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,1RN9H@1236|Gammaproteobacteria,1YDZG@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria M Catalyzes cross-linking of the peptidoglycan cell wall mrdA GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0045229,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 3.4.16.4 ko:K05515 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - iEcE24377_1341.EcE24377A_0661,iPC815.YPO2604 PBP_dimer,Transpeptidase k141_24452_2 235909.GK0798 1.6e-31 110.0 2EG5I@1|root,339XF@2|Bacteria,1VN1D@1239|Firmicutes,4HRD8@91061|Bacilli,1WGXN@129337|Geobacillus 91061|Bacilli S YjzC-like protein yjzC - - - - - - - - - - - YjzC k141_24452_3 1071073.KI530540_gene3417 5.47e-07 50.1 COG1968@1|root,COG1968@2|Bacteria,1TPFA@1239|Firmicutes,4HCE7@91061|Bacilli,1ZC3Z@1386|Bacillus 91061|Bacilli V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin uppP - 3.6.1.27 ko:K06153 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - BacA k141_35215_1 218284.CCDN010000007_gene3959 1.05e-116 336.0 COG1309@1|root,COG1309@2|Bacteria,1UZQU@1239|Firmicutes,4HD4B@91061|Bacilli,1ZBMP@1386|Bacillus 91061|Bacilli K Transcriptional regulator kstR2_2 - - - - - - - - - - - TetR_N k141_13946_1 1226325.HMPREF1548_02886 1.26e-11 67.8 2E66T@1|root,330VC@2|Bacteria,1VHCY@1239|Firmicutes,24MYI@186801|Clostridia,36NA0@31979|Clostridiaceae 186801|Clostridia S Psort location CytoplasmicMembrane, score - - - - - - - - - - - - - k141_7713_1 1042377.AFPJ01000007_gene1878 1.53e-35 128.0 COG2866@1|root,COG2866@2|Bacteria,1MYRD@1224|Proteobacteria,1T1MH@1236|Gammaproteobacteria,46D94@72275|Alteromonadaceae 1236|Gammaproteobacteria E Succinylglutamate desuccinylase / Aspartoacylase family XCC2022 - - - - - - - - - - - AstE_AspA,DUF2817,Peptidase_M14 k141_7713_2 1232683.ADIMK_3151 1.2e-82 250.0 COG1230@1|root,COG1230@2|Bacteria,1MUSS@1224|Proteobacteria,1RQ3M@1236|Gammaproteobacteria,46721@72275|Alteromonadaceae 1236|Gammaproteobacteria P Cation efflux family - - - - - - - - - - - - Cation_efflux k141_2961_1 1294265.JCM21738_613 8.41e-05 43.5 COG3290@1|root,COG3290@2|Bacteria,1V8IS@1239|Firmicutes,4HQ4T@91061|Bacilli,1ZHUN@1386|Bacillus 91061|Bacilli T Sporulation initiation phospho-transferase B, C-terminal spo0B GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K06375 ko02020,ko02024,map02020,map02024 - - - ko00000,ko00001,ko01000 - - - SPOB_a,SPOB_ab k141_9060_2 1168065.DOK_02821 1e-43 143.0 COG0011@1|root,COG0011@2|Bacteria,1N8R0@1224|Proteobacteria,1SCF3@1236|Gammaproteobacteria,1J71D@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S YKOF-related Family - - - - - - - - - - - - Thiamine_BP,Ykof k141_5560_1 218284.CCDN010000001_gene1187 1.58e-113 342.0 COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,4HA2X@91061|Bacilli,1ZCFH@1386|Bacillus 91061|Bacilli F Belongs to the formate--tetrahydrofolate ligase family fhs GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.3 ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R00943 RC00026,RC00111 ko00000,ko00001,ko00002,ko01000 - - - FTHFS k141_32645_2 218284.CCDN010000001_gene1857 3.43e-94 285.0 COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1TQ1N@1239|Firmicutes,4HATN@91061|Bacilli,1ZC5R@1386|Bacillus 91061|Bacilli S Belongs to the CinA family cinA - 3.5.1.42 ko:K03742,ko:K03743 ko00760,map00760 - R02322 RC00100 ko00000,ko00001,ko01000 - - - CinA,MoCF_biosynth k141_24453_1 861299.J421_3355 3.29e-75 234.0 COG1702@1|root,COG1702@2|Bacteria,1ZSSD@142182|Gemmatimonadetes 142182|Gemmatimonadetes T PhoH-like protein - - - ko:K06217 - - - - ko00000 - - - PhoH k141_23383_1 1453501.JELR01000002_gene328 6.84e-119 365.0 COG1629@1|root,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria,4651V@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec k141_37429_1 1273538.G159_01725 8.53e-73 221.0 COG1247@1|root,COG1247@2|Bacteria,1V4AZ@1239|Firmicutes,4HGZ3@91061|Bacilli,26EYT@186818|Planococcaceae 91061|Bacilli M COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - - - - - - - - - - Acetyltransf_1 k141_804_1 983545.Glaag_2285 4.21e-99 317.0 COG4773@1|root,COG4773@2|Bacteria,1QTXJ@1224|Proteobacteria,1T2K9@1236|Gammaproteobacteria,465FH@72275|Alteromonadaceae 1236|Gammaproteobacteria P TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_2962_1 1453501.JELR01000001_gene2884 5.64e-64 216.0 COG0657@1|root,COG3866@1|root,COG0657@2|Bacteria,COG3866@2|Bacteria,1R4AU@1224|Proteobacteria,1RQMN@1236|Gammaproteobacteria,466TB@72275|Alteromonadaceae 1236|Gammaproteobacteria I Carboxylesterase family aes - - - - - - - - - - - Abhydrolase_3,Peptidase_S9 k141_18639_1 1279017.AQYJ01000024_gene1181 2.29e-38 128.0 COG2906@1|root,COG2906@2|Bacteria,1NGGY@1224|Proteobacteria,1SGGM@1236|Gammaproteobacteria,4690S@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG2906 Bacterioferritin-associated ferredoxin bfd - - ko:K02192 - - - - ko00000 - - - Fer2_BFD k141_18639_3 1279017.AQYJ01000024_gene1183 2.23e-183 519.0 COG1680@1|root,COG1680@2|Bacteria,1MY01@1224|Proteobacteria,1RNUI@1236|Gammaproteobacteria,464GK@72275|Alteromonadaceae 1236|Gammaproteobacteria V COG1680 Beta-lactamase class C and other penicillin binding proteins ampC - 3.5.2.6 ko:K01467 ko01501,ko02020,map01501,map02020 M00628 R06363 RC01499 ko00000,ko00001,ko00002,ko01000 - - - Beta-lactamase k141_27086_1 1116375.VEJY3_05830 1.36e-43 142.0 2AWNM@1|root,31NJE@2|Bacteria,1QKA4@1224|Proteobacteria,1TIDN@1236|Gammaproteobacteria,1XYXW@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_27086_2 1116375.VEJY3_05825 2.82e-51 162.0 COG3313@1|root,COG3313@2|Bacteria,1NGD5@1224|Proteobacteria,1SCBM@1236|Gammaproteobacteria,1XYE2@135623|Vibrionales 135623|Vibrionales S Fe-S protein - - - ko:K06938 - - - - ko00000 - - - DUF1289 k141_27086_3 1116375.VEJY3_05820 1.31e-96 281.0 COG3187@1|root,COG3187@2|Bacteria,1RFSD@1224|Proteobacteria,1S6MZ@1236|Gammaproteobacteria,1XWWJ@135623|Vibrionales 135623|Vibrionales O heat shock protein hslJ - - ko:K03668 - - - - ko00000 - - - META k141_27086_4 1280001.BAOA01000078_gene3129 8.03e-11 60.1 COG4566@1|root,COG4566@2|Bacteria,1N6WR@1224|Proteobacteria,1S0TV@1236|Gammaproteobacteria,1XV10@135623|Vibrionales 135623|Vibrionales K helix_turn_helix, Lux Regulon - - - ko:K13041 ko02020,map02020 M00514 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg k141_25796_1 315749.Bcer98_1870 1.48e-17 81.3 COG1167@1|root,COG1167@2|Bacteria,1TPS5@1239|Firmicutes,4HB1C@91061|Bacilli,1ZASA@1386|Bacillus 91061|Bacilli K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs - - - ko:K18907 - M00700,M00702 - - ko00000,ko00002,ko01504,ko03000 - - - Aminotran_1_2,GntR k141_25796_2 1196029.ALIM01000034_gene1866 4.04e-82 247.0 COG3142@1|root,COG3142@2|Bacteria,1UYI8@1239|Firmicutes,4IR0G@91061|Bacilli,1ZHIS@1386|Bacillus 91061|Bacilli P Participates in the control of copper homeostasis cutC - - ko:K06201 - - - - ko00000 - - - CutC k141_9083_1 1042377.AFPJ01000052_gene1567 2.36e-24 96.3 COG3767@1|root,COG3767@2|Bacteria 2|Bacteria - - - - 3.2.1.4 ko:K01179 ko00500,ko01100,map00500,map01100 - R06200,R11307,R11308 - ko00000,ko00001,ko01000 - GH5,GH9 - EF-hand_5 k141_13975_2 1279017.AQYJ01000029_gene3802 7.3e-45 157.0 COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,1RMSE@1236|Gammaproteobacteria,464G9@72275|Alteromonadaceae 1236|Gammaproteobacteria EH COG0147 Anthranilate para-aminobenzoate synthases component I pabB GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.6.1.85 ko:K01665 ko00790,map00790 - R01716 RC00010,RC01418 ko00000,ko00001,ko01000 - - iEC042_1314.EC042_1977 Anth_synt_I_N,Chorismate_bind k141_820_1 218284.CCDN010000007_gene3813 1.38e-139 403.0 COG4241@1|root,COG4241@2|Bacteria,1UZYE@1239|Firmicutes,4HAFH@91061|Bacilli,1ZC1B@1386|Bacillus 91061|Bacilli S membrane yybS - - - - - - - - - - - DUF2232 k141_27863_1 666686.B1NLA3E_06810 1.75e-42 145.0 COG1692@1|root,COG1692@2|Bacteria,1TR9P@1239|Firmicutes,4HAV5@91061|Bacilli,1ZC3D@1386|Bacillus 91061|Bacilli S protein conserved in bacteria ymdB GO:0003674,GO:0003824,GO:0004112,GO:0004113,GO:0008081,GO:0016787,GO:0016788,GO:0042578 - ko:K02029,ko:K02030,ko:K09769 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - YmdB k141_7728_1 1132509.C447_15036 4.9e-10 62.4 arCOG01846@1|root,arCOG01846@2157|Archaea,2Y86N@28890|Euryarchaeota,2415P@183963|Halobacteria 183963|Halobacteria D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP mrp1 - - ko:K03593 - - - - ko00000,ko03029,ko03036 - - - FeS_assembly_P,ParA k141_12775_1 218284.CCDN010000001_gene1249 3.02e-126 366.0 COG0707@1|root,COG0707@2|Bacteria,1TQFT@1239|Firmicutes,4HBAQ@91061|Bacilli,1ZBA5@1386|Bacillus 91061|Bacilli M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) murG - 2.4.1.227 ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 - R05032,R05662 RC00005,RC00049 ko00000,ko00001,ko01000,ko01011 - GT28 - Glyco_tran_28_C,Glyco_transf_28 k141_18659_1 1177154.Y5S_01706 2.92e-115 383.0 COG1361@1|root,COG1361@2|Bacteria,1QVSF@1224|Proteobacteria 1224|Proteobacteria M domain protein - - - - - - - - - - - - CARDB,DUF11,OmpA_membrane k141_27117_2 1453501.JELR01000001_gene2720 2.8e-53 168.0 COG2329@1|root,COG2329@2|Bacteria,1N861@1224|Proteobacteria,1SC9H@1236|Gammaproteobacteria,468QF@72275|Alteromonadaceae 1236|Gammaproteobacteria S enzyme involved in biosynthesis of extracellular polysaccharides - - - - - - - - - - - - ABM k141_27117_3 998088.B565_3081 1.07e-05 47.0 COG3571@1|root,COG3571@2|Bacteria,1RD20@1224|Proteobacteria,1S3Y4@1236|Gammaproteobacteria,1Y5NM@135624|Aeromonadales 135624|Aeromonadales S Alpha/beta hydrolase family - - - ko:K07020 - - - - ko00000 - - - Abhydrolase_6 k141_20805_1 42565.FP66_07740 1.11e-133 382.0 COG1586@1|root,COG1586@2|Bacteria,1MXPT@1224|Proteobacteria,1RQSX@1236|Gammaproteobacteria,1XHD5@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine speD - 4.1.1.50 ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 M00034,M00133 R00178 RC00299 ko00000,ko00001,ko00002,ko01000 - - - AdoMet_dc k141_25797_1 1227349.C170_00964 1.19e-90 276.0 COG0477@1|root,COG2814@2|Bacteria,1UZTY@1239|Firmicutes,4HESQ@91061|Bacilli,26TEP@186822|Paenibacillaceae 91061|Bacilli EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1,Sugar_tr k141_32663_1 218284.CCDN010000001_gene277 9.59e-216 602.0 COG4565@1|root,COG4565@2|Bacteria,1TS2Z@1239|Firmicutes,4HCJ5@91061|Bacilli,1ZANG@1386|Bacillus 91061|Bacilli KT transcriptional regulatory protein - - - - - - - - - - - - HTH_11 k141_32663_2 1382305.AZUC01000063_gene3343 1.01e-06 49.7 COG4948@1|root,COG4948@2|Bacteria,1TQMS@1239|Firmicutes,4HCY5@91061|Bacilli,26D9S@186818|Planococcaceae 91061|Bacilli M Belongs to the mandelate racemase muconate lactonizing enzyme family - - - - - - - - - - - - MR_MLE_C,MR_MLE_N k141_37438_1 1294265.JCM21738_1689 4.84e-102 298.0 COG1434@1|root,COG1434@2|Bacteria,1VA42@1239|Firmicutes,4HP7F@91061|Bacilli,1ZH5E@1386|Bacillus 91061|Bacilli S DUF218 domain - - - - - - - - - - - - DUF218 k141_37438_2 1294265.JCM21738_1690 1.04e-05 46.2 28XAZ@1|root,2ZJ8Y@2|Bacteria,1V2XT@1239|Firmicutes,4HGD4@91061|Bacilli,1ZG66@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_16123_1 218284.CCDN010000001_gene663 1.99e-48 157.0 COG5416@1|root,COG5416@2|Bacteria,1VGMG@1239|Firmicutes,4HQ29@91061|Bacilli,1ZIY0@1386|Bacillus 91061|Bacilli S Lipopolysaccharide assembly protein A domain yrvD - - - - - - - - - - - LapA_dom k141_16123_2 218284.CCDN010000001_gene662 2.89e-171 482.0 COG0053@1|root,COG0053@2|Bacteria,1TSGY@1239|Firmicutes,4H9WP@91061|Bacilli,1ZAPN@1386|Bacillus 91061|Bacilli P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family czcD - - - - - - - - - - - Cation_efflux,ZT_dimer k141_7729_1 218284.CCDN010000001_gene1524 6.85e-153 451.0 COG0550@1|root,COG0550@2|Bacteria,1TPJD@1239|Firmicutes,4HAZV@91061|Bacilli,1ZBEG@1386|Bacillus 91061|Bacilli L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topB - 5.99.1.2 ko:K03169 - - - - ko00000,ko01000,ko03032 - - - Topoisom_bac,Toprim,Toprim_Crpt k141_27118_1 997296.PB1_00805 6.83e-107 313.0 COG2188@1|root,COG2188@2|Bacteria,1TQQQ@1239|Firmicutes,4H9TG@91061|Bacilli,1ZB5M@1386|Bacillus 91061|Bacilli K Transcriptional regulator ymfC - - ko:K03710 - - - - ko00000,ko03000 - - - GntR,UTRA k141_30237_1 665959.HMPREF1013_00090 8.56e-112 325.0 COG4430@1|root,COG4430@2|Bacteria,1V41W@1239|Firmicutes,4HDKN@91061|Bacilli,1ZC25@1386|Bacillus 91061|Bacilli S Bacteriocin-protection, YdeI or OmpD-Associated - - - - - - - - - - - - OmdA k141_30237_2 1051501.AYTL01000030_gene2907 9.25e-76 229.0 COG0454@1|root,COG0454@2|Bacteria,1V4EA@1239|Firmicutes,4HHBF@91061|Bacilli,1ZGG7@1386|Bacillus 91061|Bacilli K acetyltransferase ysnE GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031248,GO:0031365,GO:0032991,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564,GO:1902493,GO:1902494,GO:1990234 - ko:K03829 - - - - ko00000,ko01000 - - - Acetyltransf_1 k141_30237_3 1294265.JCM21738_4655 1.86e-19 82.4 COG2353@1|root,COG2353@2|Bacteria,1V1NX@1239|Firmicutes,4HFXF@91061|Bacilli,1ZCU9@1386|Bacillus 91061|Bacilli S Belongs to the UPF0312 family - - - - - - - - - - - - YceI k141_5583_1 1042377.AFPJ01000020_gene2057 1.02e-65 218.0 COG1502@1|root,COG1502@2|Bacteria,1MUDJ@1224|Proteobacteria,1RMIF@1236|Gammaproteobacteria,4649V@72275|Alteromonadaceae 1236|Gammaproteobacteria I Phospholipase D. Active site motifs. - - - ko:K06132 ko00564,ko01100,map00564,map01100 - R11062 RC00017 ko00000,ko00001,ko01000 - - - PLDc_2 k141_4250_1 1453501.JELR01000002_gene1321 4.36e-62 199.0 COG2197@1|root,COG2197@2|Bacteria 2|Bacteria K response regulator - - - - - - - - - - - - GerE,PAS_3 k141_13978_1 218284.CCDN010000004_gene3052 4.12e-65 207.0 COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,4HG3V@91061|Bacilli,1ZFYF@1386|Bacillus 91061|Bacilli E ATPases associated with a variety of cellular activities - - 3.6.3.25,3.6.3.30 ko:K02010,ko:K02045 ko00920,ko02010,map00920,map02010 M00185,M00190 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.10,3.A.1.6.1,3.A.1.6.3 - - ABC_tran k141_13978_2 218284.CCDN010000004_gene3051 2.01e-71 219.0 COG0398@1|root,COG0398@2|Bacteria,1V3J1@1239|Firmicutes,4HHXX@91061|Bacilli,1ZEPX@1386|Bacillus 91061|Bacilli S SNARE associated Golgi protein ytxB - - - - - - - - - - - SNARE_assoc k141_20806_1 1131730.BAVI_06514 3.32e-33 126.0 COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HB3V@91061|Bacilli,1ZB8V@1386|Bacillus 91061|Bacilli IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II alkK - - ko:K00666 - - - - ko00000,ko01000,ko01004 - - - AMP-binding,AMP-binding_C k141_11522_1 379066.GAU_0665 8.62e-55 183.0 COG1559@1|root,COG1559@2|Bacteria,1ZTA7@142182|Gemmatimonadetes 142182|Gemmatimonadetes S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation mltG - - ko:K07082 - - - - ko00000 - - - YceG k141_19746_1 105425.BBPL01000007_gene7411 3.77e-10 64.3 COG1574@1|root,COG1574@2|Bacteria,2GJVW@201174|Actinobacteria,2NHRC@228398|Streptacidiphilus 201174|Actinobacteria S Amidohydrolase family - - - - - - - - - - - - Amidohydro_3 k141_19746_3 686578.AFFX01000014_gene1901 1.35e-47 157.0 2EFFX@1|root,3398N@2|Bacteria,1NCKU@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_19746_4 1042377.AFPJ01000028_gene2272 2.44e-297 827.0 COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,464J7@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0405 Gamma-glutamyltransferase ggt - 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept k141_27864_1 1042377.AFPJ01000015_gene1614 1.29e-213 605.0 COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,1RMT7@1236|Gammaproteobacteria,4640X@72275|Alteromonadaceae 1236|Gammaproteobacteria S Bacterial protein of unknown function (DUF885) - - - - - - - - - - - - DUF885 k141_34006_1 1298593.TOL_3717 2.36e-117 346.0 COG0583@1|root,COG0583@2|Bacteria,1MVHT@1224|Proteobacteria,1RN7G@1236|Gammaproteobacteria,1XHJV@135619|Oceanospirillales 135619|Oceanospirillales K transcriptional regulator - - - ko:K03717 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate k141_34006_2 1298593.TOL_3716 2.9e-26 111.0 COG1009@1|root,COG1009@2|Bacteria,1MW9F@1224|Proteobacteria,1RN54@1236|Gammaproteobacteria,1XIDF@135619|Oceanospirillales 135619|Oceanospirillales CP Proton-conducting membrane transporter - - 1.6.5.3 ko:K05577 ko00190,ko01100,map00190,map01100 M00145 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 - - - Proton_antipo_M k141_37439_1 218284.CCDN010000005_gene3343 1.22e-165 472.0 COG3104@1|root,COG3104@2|Bacteria,1TP81@1239|Firmicutes,4HAF2@91061|Bacilli,1ZAVZ@1386|Bacillus 91061|Bacilli E amino acid peptide transporter - - - ko:K03305 - - - - ko00000 2.A.17 - - PTR2 k141_18662_1 218284.CCDN010000002_gene2007 5.38e-179 508.0 COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,4H9VZ@91061|Bacilli,1ZC2Y@1386|Bacillus 91061|Bacilli E acetylornithine aminotransferase argD GO:0003674,GO:0003824,GO:0003992,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.11,2.6.1.17 ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R02283,R04475 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 k141_10352_1 1120973.AQXL01000119_gene527 2.76e-55 184.0 COG0294@1|root,COG0294@2|Bacteria,1TPKT@1239|Firmicutes,4H9SY@91061|Bacilli,277X0@186823|Alicyclobacillaceae 91061|Bacilli H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives folP GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.15 ko:K00796 ko00790,ko01100,map00790,map01100 M00126,M00841 R03066,R03067 RC00121,RC00842 ko00000,ko00001,ko00002,ko01000 - - - Pterin_bind k141_24673_1 1307436.PBF_21603 5.45e-156 445.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HAWZ@91061|Bacilli,1ZCGC@1386|Bacillus 91061|Bacilli I acyl-CoA dehydrogenase yngJ - 1.3.8.1 ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 - R01175,R01178,R02661,R03172,R04751 RC00052,RC00068,RC00076,RC00120,RC00148 ko00000,ko00001,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_14253_1 314285.KT71_11675 1.63e-177 525.0 COG3544@1|root,COG3544@2|Bacteria,1NTI3@1224|Proteobacteria,1T0HG@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF4142) - - - - - - - - - - - - DUF305 k141_14253_2 392500.Swoo_0696 3.19e-119 352.0 COG2819@1|root,COG2819@2|Bacteria 2|Bacteria S hydrolase activity, acting on ester bonds besA - - ko:K07017 - - - - ko00000 - - - Esterase k141_14253_3 1207075.PputUW4_00835 1.27e-16 77.0 COG1544@1|root,COG1544@2|Bacteria,1N9T3@1224|Proteobacteria,1SDXP@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Ribosomal subunit interface protein - - - - - - - - - - - - Ribosomal_S30AE k141_14253_4 1453501.JELR01000001_gene2684 5.08e-152 434.0 COG0412@1|root,COG0412@2|Bacteria,1NRB4@1224|Proteobacteria,1SBI0@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q Dienelactone hydrolase - - 3.1.1.45 ko:K01061 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 - R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222 RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 - - - DLH k141_14253_5 1279017.AQYJ01000024_gene1160 3.03e-273 757.0 COG1473@1|root,COG1473@2|Bacteria,1MX6N@1224|Proteobacteria,1RP3N@1236|Gammaproteobacteria,46405@72275|Alteromonadaceae 1236|Gammaproteobacteria S Peptidase dimerisation domain abgB - - ko:K12941 - - - - ko00000,ko01002 - - - M20_dimer,Peptidase_M20 k141_14253_6 566466.NOR53_2606 1.34e-91 280.0 COG4313@1|root,COG4313@2|Bacteria,1MWCX@1224|Proteobacteria,1S4A1@1236|Gammaproteobacteria 1236|Gammaproteobacteria C COG4313 Protein involved in meta-pathway of phenol degradation - - - - - - - - - - - - Phenol_MetA_deg k141_14253_7 998674.ATTE01000001_gene1133 3.65e-76 234.0 COG3449@1|root,COG3449@2|Bacteria,1RF2U@1224|Proteobacteria,1S2JU@1236|Gammaproteobacteria,462KN@72273|Thiotrichales 72273|Thiotrichales L SOUL heme-binding protein - - - - - - - - - - - - SOUL k141_14253_8 236097.ADG881_1028 3.09e-282 782.0 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1RMQ4@1236|Gammaproteobacteria,1XICJ@135619|Oceanospirillales 135619|Oceanospirillales IQ involved in the beta-oxidation of n-alkanoic and n-phenylalkanoic acids fadD - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding,AMP-binding_C k141_14253_9 95619.PM1_0224430 8.98e-104 310.0 COG0300@1|root,COG0300@2|Bacteria,1R9VQ@1224|Proteobacteria,1S1WG@1236|Gammaproteobacteria 1236|Gammaproteobacteria S KR domain - - - - - - - - - - - - adh_short k141_14253_10 95619.PM1_0224425 3.99e-160 458.0 COG0451@1|root,COG0451@2|Bacteria 2|Bacteria GM ADP-glyceromanno-heptose 6-epimerase activity - - - ko:K21793 ko00333,ko01130,map00333,map01130 M00838 R11663,R11666 - ko00000,ko00001,ko00002 - - - Epimerase k141_14253_11 95619.PM1_0224420 6.89e-87 259.0 COG1917@1|root,COG1917@2|Bacteria,1RB86@1224|Proteobacteria,1S21T@1236|Gammaproteobacteria 1236|Gammaproteobacteria S PFAM Cupin 2 conserved barrel domain protein - - - - - - - - - - - - - k141_30358_1 1294265.JCM21738_2002 4.83e-78 236.0 COG4191@1|root,COG4191@2|Bacteria,1UZ9W@1239|Firmicutes,4HDK2@91061|Bacilli,1ZD85@1386|Bacillus 91061|Bacilli T Histidine kinase kinB - 2.7.13.3 ko:K07697 ko02020,map02020 M00485 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - 5TM-5TMR_LYT,HATPase_c,HisKA k141_30358_2 1294265.JCM21738_2003 2.67e-30 107.0 2EH2H@1|root,33AUF@2|Bacteria,1VKXK@1239|Firmicutes,4HRIP@91061|Bacilli,1ZKGU@1386|Bacillus 91061|Bacilli S Belongs to the SspH family sspH - - ko:K06425 - - - - ko00000 - - - SspH k141_6946_1 586416.GZ22_17245 1.9e-115 342.0 COG0719@1|root,COG0719@2|Bacteria,1TQ21@1239|Firmicutes,4HA1Z@91061|Bacilli 91061|Bacilli O assembly protein SufB sufB - - ko:K07033,ko:K09014 - - - - ko00000 - - - UPF0051 k141_16295_1 218284.CCDN010000002_gene2891 1.31e-119 346.0 COG1120@1|root,COG1120@2|Bacteria,1TP2Q@1239|Firmicutes,4HADG@91061|Bacilli,1ZBMI@1386|Bacillus 91061|Bacilli HP ABC transporter fhuC - 3.6.3.34 ko:K02013 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 - - ABC_tran k141_23698_1 218284.CCDN010000007_gene3955 3.39e-113 334.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,1ZBYG@1386|Bacillus 91061|Bacilli I Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation mmgA GO:0003674,GO:0003824,GO:0003988,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - iYO844.BSU24170 Thiolase_C,Thiolase_N k141_37567_1 218284.CCDN010000001_gene1121 1.37e-29 115.0 COG0457@1|root,COG0457@2|Bacteria,1TT97@1239|Firmicutes,4HAIA@91061|Bacilli,1ZAZM@1386|Bacillus 91061|Bacilli S COG0457 FOG TPR repeat ypiA - - - - - - - - - - - TPR_16,TPR_19,TPR_2,TPR_7,TPR_8 k141_37567_2 1408303.JNJJ01000054_gene1405 5.81e-58 195.0 2E49C@1|root,32Z54@2|Bacteria,1VH6M@1239|Firmicutes,4HQD6@91061|Bacilli,1ZDJG@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_37567_3 218284.CCDN010000001_gene1119 1.08e-55 186.0 COG0128@1|root,COG0128@2|Bacteria,1TPIH@1239|Firmicutes,4HBHZ@91061|Bacilli,1ZBP0@1386|Bacillus 91061|Bacilli E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate aroA GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03460 RC00350 ko00000,ko00001,ko00002,ko01000 - - - EPSP_synthase k141_1006_2 1294265.JCM21738_4880 5.78e-101 300.0 COG0470@1|root,COG0470@2|Bacteria,1TRVS@1239|Firmicutes,4HA3T@91061|Bacilli,1ZBDA@1386|Bacillus 91061|Bacilli L DNA polymerase III holB GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576 2.7.7.7 ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNApol3-delta_C k141_9362_2 218284.CCDN010000005_gene3359 1.88e-51 181.0 2E3R1@1|root,32YNU@2|Bacteria,1VEND@1239|Firmicutes,4HNII@91061|Bacilli,1ZFAW@1386|Bacillus 91061|Bacilli S Anti-sigma factor N-terminus rsgI - - - - - - - - - - - RsgI_N k141_27992_1 218284.CCDN010000002_gene2060 5.35e-94 288.0 COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,4H9SZ@91061|Bacilli,1ZAX7@1386|Bacillus 91061|Bacilli E Sodium alanine symporter - - - ko:K03310 - - - - ko00000 2.A.25 - - Na_Ala_symp k141_36347_1 224308.BSU12970 4.66e-99 297.0 COG1619@1|root,COG1619@2|Bacteria,1TRBB@1239|Firmicutes,4HAWT@91061|Bacilli,1ZC09@1386|Bacillus 91061|Bacilli V proteins, homologs of microcin C7 resistance protein MccF ykfA - 3.4.17.13 ko:K01297 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_S66 k141_6947_1 218284.CCDN010000001_gene1171 3.85e-100 299.0 COG3424@1|root,COG3424@2|Bacteria,1TPUK@1239|Firmicutes,4HBHH@91061|Bacilli,1ZC8W@1386|Bacillus 91061|Bacilli Q Naringenin-chalcone synthase bcsA - - ko:K16167 - - - - ko00000,ko01008 - - - Chal_sti_synt_C,Chal_sti_synt_N k141_19953_1 1453501.JELR01000001_gene2905 3.72e-131 385.0 COG2067@1|root,COG2067@2|Bacteria,1MUU4@1224|Proteobacteria,1RQZJ@1236|Gammaproteobacteria,465E0@72275|Alteromonadaceae 1236|Gammaproteobacteria I Long-chain fatty acid fadL GO:0003674,GO:0005215,GO:0005319,GO:0005324,GO:0005342,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006820,GO:0006869,GO:0008028,GO:0008150,GO:0008509,GO:0008514,GO:0009279,GO:0010876,GO:0015075,GO:0015245,GO:0015267,GO:0015288,GO:0015318,GO:0015483,GO:0015711,GO:0015718,GO:0015849,GO:0015908,GO:0015909,GO:0016020,GO:0019867,GO:0022803,GO:0022829,GO:0022834,GO:0022836,GO:0022857,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0034220,GO:0044462,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098656,GO:1903825,GO:1905039 - ko:K06076 - - - - ko00000,ko02000 1.B.9 - iECs_1301.ECs3227,iG2583_1286.G2583_2880,iZ_1308.Z3608 Toluene_X k141_22354_1 1294265.JCM21738_1754 9.15e-90 270.0 COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H9SA@91061|Bacilli,1ZN0B@1386|Bacillus 91061|Bacilli M Transglycosylase pbpG GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.4.1.129,3.4.16.4 ko:K21464 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase k141_32887_2 218284.CCDN010000001_gene576 3.66e-132 375.0 COG2009@1|root,COG2009@2|Bacteria,1TQUI@1239|Firmicutes,4HBX0@91061|Bacilli,1ZBB5@1386|Bacillus 91061|Bacilli C succinate dehydrogenase sdhC - - ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002 - - iYO844.BSU28450 Sdh_cyt k141_23699_1 1294265.JCM21738_3368 1.57e-44 145.0 2E5KF@1|root,330BM@2|Bacteria,1VEYE@1239|Firmicutes,4HNR3@91061|Bacilli,1ZISS@1386|Bacillus 91061|Bacilli S Small, acid-soluble spore proteins, alpha/beta type - - - - - - - - - - - - SASP k141_1007_1 326297.Sama_0366 1.46e-06 49.3 COG0237@1|root,COG0237@2|Bacteria,1RCXT@1224|Proteobacteria,1S3NR@1236|Gammaproteobacteria,2Q9KS@267890|Shewanellaceae 1236|Gammaproteobacteria H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A coaE GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 ko:K00859 ko00770,ko01100,map00770,map01100 M00120 R00130 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - iECP_1309.ECP_0104 CoaE k141_1007_2 1042377.AFPJ01000034_gene2407 4.19e-38 128.0 COG3024@1|root,COG3024@2|Bacteria,1NGJ8@1224|Proteobacteria,1SC7M@1236|Gammaproteobacteria,468WS@72275|Alteromonadaceae 1236|Gammaproteobacteria S Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase yacG GO:0003674,GO:0004857,GO:0005488,GO:0008150,GO:0008270,GO:0008657,GO:0010911,GO:0030234,GO:0032780,GO:0042030,GO:0043086,GO:0043167,GO:0043169,GO:0043462,GO:0044092,GO:0046872,GO:0046914,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0072586,GO:0098772,GO:2000371,GO:2000372 - ko:K09862 - - - - ko00000 - - - YacG k141_14255_1 1294265.JCM21738_2587 2.2e-121 374.0 COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,4HABE@91061|Bacilli,1ZPZA@1386|Bacillus 91061|Bacilli EF Carbamoyl-phosphate synthetase ammonia chain carB GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS k141_12904_1 1405.DJ92_797 8.54e-22 98.2 COG0454@1|root,COG1357@1|root,COG0456@2|Bacteria,COG1357@2|Bacteria,1V5QZ@1239|Firmicutes,4I2JE@91061|Bacilli,1ZDWX@1386|Bacillus 91061|Bacilli K Pentapeptide repeats (9 copies) - - - - - - - - - - - - Acetyltransf_7,Pentapeptide,Pentapeptide_4 k141_12904_2 218284.CCDN010000001_gene1756 7.42e-70 219.0 COG1443@1|root,COG1443@2|Bacteria,1V6SB@1239|Firmicutes,4HJ2T@91061|Bacilli,1ZFNY@1386|Bacillus 91061|Bacilli I COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes M1-740 - - - - - - - - - - - NUDIX k141_12904_3 218284.CCDN010000001_gene1755 2.14e-17 79.0 COG1988@1|root,COG1988@2|Bacteria,1V7MF@1239|Firmicutes,4HK3C@91061|Bacilli,1ZCTI@1386|Bacillus 91061|Bacilli S LexA-binding, inner membrane-associated putative hydrolase - - - ko:K07038 - - - - ko00000 - - - YdjM k141_22355_1 1307436.PBF_05588 2.89e-18 81.3 COG4912@1|root,COG4912@2|Bacteria,1V4WB@1239|Firmicutes,4HFXG@91061|Bacilli,1ZGCX@1386|Bacillus 91061|Bacilli L DNA alkylation repair alkD - - - - - - - - - - - DNA_alkylation k141_16296_1 218284.CCDN010000002_gene2852 2.22e-109 324.0 COG2603@1|root,COG2603@2|Bacteria,1TQ8T@1239|Firmicutes,4HBX4@91061|Bacilli,1ZCJF@1386|Bacillus 91061|Bacilli S tRNA 2-selenouridine synthase selU - - ko:K06917 - - - - ko00000,ko01000,ko03016 - - - Rhodanese k141_1910_1 1348635.BBJY01000003_gene3774 1.69e-308 847.0 28H6M@1|root,2Z7J0@2|Bacteria,1R7G5@1224|Proteobacteria,1RPZU@1236|Gammaproteobacteria,1XWJ4@135623|Vibrionales 135623|Vibrionales G Periplasmic pectate lyase - - 4.2.2.9 ko:K01731 ko00040,map00040 - R02361,R06240 RC00049,RC00705 ko00000,ko00001,ko01000 - - - Pectate_lyase_2 k141_1910_2 1348635.BBJY01000003_gene3773 9.53e-266 736.0 COG0534@1|root,COG0534@2|Bacteria,1MVRV@1224|Proteobacteria,1RNQ7@1236|Gammaproteobacteria,1XUCZ@135623|Vibrionales 135623|Vibrionales V Na driven multidrug efflux pump - - - - - - - - - - - - MatE k141_1910_3 223926.28808221 1.63e-137 390.0 COG0800@1|root,COG0800@2|Bacteria,1MUVJ@1224|Proteobacteria,1RPDF@1236|Gammaproteobacteria,1XU29@135623|Vibrionales 135623|Vibrionales G COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase - - 4.1.2.14,4.1.3.42 ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 M00008,M00061,M00308,M00631 R00470,R05605 RC00307,RC00308,RC00435 ko00000,ko00001,ko00002,ko01000 - - - Aldolase k141_1910_4 223926.28808220 7.73e-205 568.0 COG0524@1|root,COG0524@2|Bacteria,1MVG2@1224|Proteobacteria,1RNH5@1236|Gammaproteobacteria,1XSPP@135623|Vibrionales 135623|Vibrionales G COG0524 Sugar kinases, ribokinase family - - 2.7.1.45 ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 M00061,M00308,M00631 R01541 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - PfkB k141_1910_5 223926.28808219 2.87e-154 440.0 COG0657@1|root,COG0657@2|Bacteria,1N5QB@1224|Proteobacteria,1RS7Q@1236|Gammaproteobacteria,1XYZ8@135623|Vibrionales 135623|Vibrionales I alpha/beta hydrolase fold - - - - - - - - - - - - Abhydrolase_3 k141_1910_6 1116375.VEJY3_16051 1.02e-142 403.0 COG0698@1|root,COG0698@2|Bacteria,1MWIB@1224|Proteobacteria,1RPEG@1236|Gammaproteobacteria,1XSE3@135623|Vibrionales 135623|Vibrionales G Ribose-5-phosphate isomerase - - - - - - - - - - - - DUF3666,LacAB_rpiB k141_1910_7 223926.28808217 4.05e-71 214.0 COG1917@1|root,COG1917@2|Bacteria,1RHSW@1224|Proteobacteria,1S6GC@1236|Gammaproteobacteria,1XXVU@135623|Vibrionales 135623|Vibrionales S Cupin domain - - - - - - - - - - - - Cupin_2 k141_1910_8 223926.28808216 5.4e-106 307.0 28NVI@1|root,2ZBTK@2|Bacteria,1RJV0@1224|Proteobacteria,1T13I@1236|Gammaproteobacteria,1Y30Q@135623|Vibrionales 135623|Vibrionales S Bacterial inner membrane protein - - - - - - - - - - - - Imp-YgjV k141_1910_9 298386.PBPRB1737 1.64e-162 457.0 COG1028@1|root,COG1028@2|Bacteria,1MWB6@1224|Proteobacteria,1RMZB@1236|Gammaproteobacteria,1XSTX@135623|Vibrionales 135623|Vibrionales IQ Enoyl-(Acyl carrier protein) reductase - - 1.1.1.127 ko:K00065 ko00040,map00040 - R01542 RC00089 ko00000,ko00001,ko01000 - - - adh_short_C2 k141_1910_10 223926.28808214 2.94e-172 482.0 COG1414@1|root,COG1414@2|Bacteria,1MUNW@1224|Proteobacteria,1RR06@1236|Gammaproteobacteria,1XU1E@135623|Vibrionales 135623|Vibrionales K helix_turn_helix isocitrate lyase regulation kdgR - - ko:K19333,ko:K21602 - - - - ko00000,ko03000 - - - HTH_IclR,IclR k141_1910_11 223926.28808213 0.0 1103.0 COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,1RPSJ@1236|Gammaproteobacteria,1XTPG@135623|Vibrionales 135623|Vibrionales T containing cAMP-binding and CBS domains - - - ko:K07182 - - - - ko00000 - - - CBS,DUF294,DUF294_C,cNMP_binding k141_1910_12 223926.28808212 1e-127 367.0 COG0847@1|root,COG0847@2|Bacteria,1RAF1@1224|Proteobacteria,1S9PP@1236|Gammaproteobacteria,1XVPY@135623|Vibrionales 135623|Vibrionales L EXOIII - - 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - RNase_T k141_1910_13 1116375.VEJY3_16031 5.91e-199 552.0 COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,1RS6U@1236|Gammaproteobacteria,1XU3Y@135623|Vibrionales 135623|Vibrionales K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_1910_14 1116375.VEJY3_22351 5.24e-140 399.0 COG0412@1|root,COG0412@2|Bacteria,1RCWF@1224|Proteobacteria,1RY38@1236|Gammaproteobacteria,1Y26F@135623|Vibrionales 135623|Vibrionales Q Dienelactone hydrolase family - - - - - - - - - - - - DLH k141_22378_1 218284.CCDN010000004_gene3102 1.2e-129 372.0 COG1028@1|root,COG1028@2|Bacteria,1TP3G@1239|Firmicutes,4HACT@91061|Bacilli,1ZDEW@1386|Bacillus 91061|Bacilli IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate - - 1.1.1.30 ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 M00088 R01361 RC00117 ko00000,ko00001,ko00002,ko01000 - - - adh_short_C2 k141_29363_1 1116375.VEJY3_18596 0.0 1090.0 COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,1RMD2@1236|Gammaproteobacteria,1XU4R@135623|Vibrionales 135623|Vibrionales C Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate betA - 1.1.99.1 ko:K00108 ko00260,ko01100,map00260,map01100 M00555 R01025 RC00087 ko00000,ko00001,ko00002,ko01000 - - - GMC_oxred_C,GMC_oxred_N k141_29363_2 223926.28809412 1.87e-218 603.0 COG2113@1|root,COG2113@2|Bacteria,1MVIG@1224|Proteobacteria,1RRNK@1236|Gammaproteobacteria,1XTWX@135623|Vibrionales 135623|Vibrionales E COG2113 ABC-type proline glycine betaine transport systems, periplasmic components choX - - ko:K02002 ko02010,map02010 M00208 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - OpuAC k141_29363_3 223926.28809411 1.08e-185 518.0 COG4176@1|root,COG4176@2|Bacteria,1MUM4@1224|Proteobacteria,1RPQS@1236|Gammaproteobacteria,1XSGK@135623|Vibrionales 135623|Vibrionales P COG4176 ABC-type proline glycine betaine transport system, permease component choW - - ko:K02001 ko02010,map02010 M00208 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - BPD_transp_1 k141_29363_4 223926.28809410 2.12e-186 524.0 COG4175@1|root,COG4175@2|Bacteria,1MU86@1224|Proteobacteria,1RY4K@1236|Gammaproteobacteria,1Y2HJ@135623|Vibrionales 135623|Vibrionales E COG4175 ABC-type proline glycine betaine transport system, ATPase component choV - 3.6.3.32 ko:K02000 ko02010,map02010 M00208 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.12 - - ABC_tran k141_17411_1 218284.CCDN010000001_gene951 4.07e-130 377.0 COG0006@1|root,COG0006@2|Bacteria,1TQ44@1239|Firmicutes,4HAT7@91061|Bacilli,1ZB4P@1386|Bacillus 91061|Bacilli E COG0006 Xaa-Pro aminopeptidase yqhT - 3.4.11.9,3.4.13.9 ko:K01262,ko:K01271 - - - - ko00000,ko01000,ko01002 - - - Creatinase_N,Peptidase_M24 k141_17411_2 218284.CCDN010000001_gene950 7.43e-89 262.0 COG0757@1|root,COG0757@2|Bacteria,1V6E8@1239|Firmicutes,4HJ2V@91061|Bacilli,1ZG8H@1386|Bacillus 91061|Bacilli E Catalyzes a trans-dehydration via an enolate intermediate aroQ - 4.2.1.10 ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03084 RC00848 ko00000,ko00001,ko00002,ko01000 - - - DHquinase_II k141_17411_3 218284.CCDN010000001_gene949 8.02e-05 43.5 29VNZ@1|root,30H6A@2|Bacteria,1V5PG@1239|Firmicutes,4HJV5@91061|Bacilli,1ZBD8@1386|Bacillus 91061|Bacilli S Conserved membrane protein YqhR yqhR - - - - - - - - - - - YqhR k141_28002_2 981383.AEWH01000010_gene3821 3.25e-33 124.0 COG1403@1|root,COG1403@2|Bacteria 2|Bacteria V endonuclease activity - - - ko:K07451 - - - - ko00000,ko01000,ko02048 - - - DUF222,HNH,HNH_5 k141_28002_3 1121091.AUMP01000003_gene2579 9.39e-50 163.0 COG3677@1|root,COG3677@2|Bacteria,1V8R5@1239|Firmicutes,4HJMG@91061|Bacilli 91061|Bacilli L Transposase yqaQ - - - - - - - - - - - GerE,HTH_28 k141_19003_1 35841.BT1A1_1122 5.87e-49 164.0 COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4HA7I@91061|Bacilli,1ZQ89@1386|Bacillus 91061|Bacilli EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components appC - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1,OppC_N k141_19003_2 1461580.CCAS010000023_gene2413 5.02e-196 547.0 COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,4HATR@91061|Bacilli,1ZCAV@1386|Bacillus 91061|Bacilli P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components appB - - ko:K02033 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 k141_19003_3 1294265.JCM21738_2562 2.32e-17 80.5 COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,4HARF@91061|Bacilli,1ZC4E@1386|Bacillus 91061|Bacilli E COG0747 ABC-type dipeptide transport system, periplasmic component appA_2 - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 k141_37587_1 1192124.LIG30_3796 6.26e-69 215.0 COG0662@1|root,COG1476@1|root,COG0662@2|Bacteria,COG1476@2|Bacteria,1QTWE@1224|Proteobacteria,2VQIT@28216|Betaproteobacteria,1K47B@119060|Burkholderiaceae 28216|Betaproteobacteria K Cupin 2, conserved barrel domain protein - - - - - - - - - - - - Cupin_2,HTH_3,HTH_31 k141_37587_2 1453501.JELR01000001_gene2627 8.42e-23 98.2 COG0304@1|root,COG0304@2|Bacteria,1MV67@1224|Proteobacteria,1RMXJ@1236|Gammaproteobacteria,4660E@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ Beta-ketoacyl synthase, C-terminal domain - - 2.3.1.180 ko:K18473 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt k141_15086_1 1122134.KB893650_gene1 6.83e-78 252.0 COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria,1XHEB@135619|Oceanospirillales 135619|Oceanospirillales O Peptidase S8 and S53, subtilisin, kexin, sedolisin - - - ko:K14645 ko02024,map02024 - - - ko00000,ko00001,ko01000,ko01002,ko03110 - - - Peptidase_S8 k141_22379_1 1123393.KB891326_gene205 1.12e-07 53.1 COG0600@1|root,COG0600@2|Bacteria,1MV2D@1224|Proteobacteria,2W8XG@28216|Betaproteobacteria,1KSN7@119069|Hydrogenophilales 119069|Hydrogenophilales P Binding-protein-dependent transport system inner membrane component - - - - - - - - - - - - BPD_transp_1 k141_22379_2 488538.SAR116_2099 4.83e-52 171.0 COG1116@1|root,COG1116@2|Bacteria,1N7FP@1224|Proteobacteria,2TRKZ@28211|Alphaproteobacteria,4BR7S@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria P ATPases associated with a variety of cellular activities - - - ko:K02049 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - ABC_tran k141_6978_1 985665.HPL003_12550 3.5e-07 56.6 2DQ89@1|root,33587@2|Bacteria,1VHBN@1239|Firmicutes,4HP4B@91061|Bacilli,26ZN2@186822|Paenibacillaceae 91061|Bacilli S IseA DL-endopeptidase inhibitor yoeB - - - - - - - - - - - Endopep_inhib k141_6978_2 265729.GS18_0201630 5.25e-31 116.0 COG1595@1|root,COG1595@2|Bacteria,1VDSM@1239|Firmicutes,4HN8P@91061|Bacilli,1ZCXA@1386|Bacillus 91061|Bacilli K Sigma-70 region 2 - - - - - - - - - - - - Sigma70_r2,Sigma70_r4_2 k141_36361_2 1300345.LF41_2955 1.72e-21 92.8 2DEWU@1|root,2ZPJP@2|Bacteria,1P3DY@1224|Proteobacteria,1T86W@1236|Gammaproteobacteria,1XA81@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - k141_23717_1 218284.CCDN010000001_gene766 4.29e-141 407.0 COG0327@1|root,COG0327@2|Bacteria,1TQ27@1239|Firmicutes,4H9NY@91061|Bacilli,1ZAPV@1386|Bacillus 91061|Bacilli S Belongs to the GTP cyclohydrolase I type 2 NIF3 family yqfO GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - - - - - - - - - - NIF3 k141_10455_1 1294265.JCM21738_3904 1.44e-148 432.0 COG1680@1|root,COG1680@2|Bacteria,1U828@1239|Firmicutes,4HA0Q@91061|Bacilli,1ZBJ0@1386|Bacillus 91061|Bacilli V Belongs to the UPF0214 family estB - - - - - - - - - - - Beta-lactamase,Peptidase_M6 k141_5747_1 218284.CCDN010000002_gene2662 3.76e-113 335.0 COG1055@1|root,COG1055@2|Bacteria,1TPNN@1239|Firmicutes,4H9WV@91061|Bacilli,1ZBHC@1386|Bacillus 91061|Bacilli P Involved in arsenical resistance. Thought to form the channel of an arsenite pump ydfA - - ko:K03893 - - - - ko00000,ko02000 2.A.45.1,3.A.4.1 - - ArsB k141_22380_1 1042377.AFPJ01000044_gene628 5.4e-82 252.0 COG3178@1|root,COG3178@2|Bacteria,1MXCH@1224|Proteobacteria,1RQ1Q@1236|Gammaproteobacteria,466NT@72275|Alteromonadaceae 1236|Gammaproteobacteria S phosphotransferase related to Ser Thr protein kinases - GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006022,GO:0006040,GO:0006082,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 2.7.1.221 ko:K07102 ko00520,ko01100,map00520,map01100 - R08968,R11024 RC00002,RC00078 ko00000,ko00001,ko01000 - - - APH k141_11737_1 218284.CCDN010000001_gene808 1.56e-97 296.0 2BAY9@1|root,324E2@2|Bacteria,1V8TN@1239|Firmicutes,4HJ42@91061|Bacilli,1ZESD@1386|Bacillus 91061|Bacilli - - yqgU - - - - - - - - - - - - k141_20952_2 1279017.AQYJ01000023_gene3230 9.47e-257 707.0 COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,1RMY3@1236|Gammaproteobacteria,464DG@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) tgt GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0008479,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 ko:K00773 - - R03789,R10209 RC00063 ko00000,ko01000,ko03016 - - iECW_1372.ECW_m0475,iWFL_1372.ECW_m0475 TGT k141_16314_2 1042377.AFPJ01000035_gene2630 1.95e-34 133.0 COG0457@1|root,COG0457@2|Bacteria,1RC07@1224|Proteobacteria,1S36N@1236|Gammaproteobacteria,46864@72275|Alteromonadaceae 1236|Gammaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_8 k141_15087_1 111781.Lepto7376_0932 1.15e-121 357.0 COG0451@1|root,COG0451@2|Bacteria,1G0TM@1117|Cyanobacteria,1H797@1150|Oscillatoriales 1117|Cyanobacteria GM NAD dependent epimerase dehydratase family sqdB - 3.13.1.1 ko:K06118 ko00520,ko00561,map00520,map00561 - R05775 RC01469 ko00000,ko00001,ko01000 - - - Epimerase k141_12917_1 1453501.JELR01000005_gene1575 9.59e-178 518.0 COG1175@1|root,COG2182@1|root,COG1175@2|Bacteria,COG2182@2|Bacteria,1MXKR@1224|Proteobacteria,1RN6B@1236|Gammaproteobacteria,46801@72275|Alteromonadaceae 1236|Gammaproteobacteria G COG1175 ABC-type sugar transport systems, permease components malF GO:0003674,GO:0003824,GO:0005215,GO:0005363,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006950,GO:0006974,GO:0008150,GO:0008643,GO:0009987,GO:0015144,GO:0015154,GO:0015157,GO:0015399,GO:0015405,GO:0015422,GO:0015423,GO:0015766,GO:0015768,GO:0015772,GO:0015774,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0033037,GO:0033554,GO:0034219,GO:0042623,GO:0042626,GO:0042956,GO:0043190,GO:0043211,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990060,GO:1990351 - ko:K10109,ko:K15771 ko02010,map02010 M00194,M00491 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.1,3.A.1.1.16,3.A.1.1.2,3.A.1.1.22 - iZ_1308.Z5631 BPD_transp_1,MalF_P2 k141_1912_1 1382304.JNIL01000001_gene308 1.04e-61 206.0 COG0334@1|root,COG0334@2|Bacteria,1TQU2@1239|Firmicutes,4HAB2@91061|Bacilli,27949@186823|Alicyclobacillaceae 91061|Bacilli E Belongs to the Glu Leu Phe Val dehydrogenases family - - 1.4.1.9 ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 - R01088,R01434,R02196 RC00006,RC00036 ko00000,ko00001,ko01000 - - - ELFV_dehydrog,ELFV_dehydrog_N k141_30367_1 1042377.AFPJ01000034_gene2316 4.64e-59 193.0 COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,1RMVY@1236|Gammaproteobacteria,465WX@72275|Alteromonadaceae 1236|Gammaproteobacteria G Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions pfp - 2.7.1.11,2.7.1.90 ko:K21071 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 - R00756,R00764,R02073,R03236,R04779 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PFK k141_30367_2 1453501.JELR01000001_gene3098 6.05e-78 244.0 COG0174@1|root,COG0174@2|Bacteria,1MU6V@1224|Proteobacteria,1RRRW@1236|Gammaproteobacteria,46CEY@72275|Alteromonadaceae 1236|Gammaproteobacteria E Glutamine synthetase, catalytic domain - - - - - - - - - - - - Gln-synt_C k141_31513_2 218284.CCDN010000001_gene941 5.83e-121 357.0 COG0403@1|root,COG0403@2|Bacteria,1TQGG@1239|Firmicutes,4HA7P@91061|Bacilli,1ZB0H@1386|Bacillus 91061|Bacilli E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor gcvPA - 1.4.4.2 ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 - R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko01000 - - - GDC-P k141_28004_1 218284.CCDN010000001_gene1456 2.01e-146 423.0 COG1823@1|root,COG1823@2|Bacteria,1UPUK@1239|Firmicutes,4HAJY@91061|Bacilli,1ZB7C@1386|Bacillus 91061|Bacilli U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family tcyP - - ko:K06956 - - - - ko00000 - - - SDF k141_16315_1 221109.22775914 1.45e-60 210.0 COG1404@1|root,COG1404@2|Bacteria,1TPH1@1239|Firmicutes,4HBQH@91061|Bacilli,23IZR@182709|Oceanobacillus 91061|Bacilli O PA domain prtS - 3.4.21.110,3.4.21.96 ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 - - - ko00000,ko00001,ko01000,ko01002,ko03110 - - - FIVAR,Gram_pos_anchor,Inhibitor_I9,PA,Peptidase_S8,SLH,YSIRK_signal,fn3_5 k141_15088_1 1294265.JCM21738_1701 3.33e-18 81.6 COG1131@1|root,COG1131@2|Bacteria,1TPQW@1239|Firmicutes,4HA3P@91061|Bacilli,1ZCNQ@1386|Bacillus 91061|Bacilli V ABC transporter, ATP-binding protein potA5 - - ko:K01990,ko:K16921 ko02010,map02010 M00254,M00584 - - ko00000,ko00001,ko00002,ko02000 3.A.1 - - ABC_tran k141_15088_2 1294265.JCM21738_1702 1.44e-99 307.0 COG1277@1|root,COG1277@2|Bacteria,1TRJ8@1239|Firmicutes,4HA9I@91061|Bacilli,1ZCXM@1386|Bacillus 91061|Bacilli S ABC-type transport system involved in multi-copper enzyme maturation permease component - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - - k141_22381_1 218284.CCDN010000008_gene4210 1.54e-83 257.0 COG3641@1|root,COG3641@2|Bacteria,1TS5F@1239|Firmicutes,4HC7U@91061|Bacilli,1ZCS4@1386|Bacillus 91061|Bacilli S Phosphotransferase system, EIIC - - - ko:K07035 - - - - ko00000 - - - PTS_EIIC_2 k141_24706_1 935836.JAEL01000024_gene2401 4.8e-120 353.0 COG0642@1|root,COG0642@2|Bacteria,1TQSG@1239|Firmicutes,4ISJC@91061|Bacilli,1ZS73@1386|Bacillus 91061|Bacilli T Signal transduction histidine kinase bceS - 2.7.13.3 ko:K11629 ko02020,map02020 M00469,M00738 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c k141_34197_1 1453501.JELR01000002_gene645 1.45e-134 388.0 COG0697@1|root,COG0697@2|Bacteria,1MWMC@1224|Proteobacteria,1RQST@1236|Gammaproteobacteria,464KV@72275|Alteromonadaceae 1236|Gammaproteobacteria EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily yigM GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - EamA k141_34197_2 1453501.JELR01000002_gene666 8.04e-213 595.0 COG0624@1|root,COG0624@2|Bacteria,1MVBR@1224|Proteobacteria,1RNDG@1236|Gammaproteobacteria,4653S@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the peptidase M20A family. ArgE subfamily argE GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0008777,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019752,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0046914,GO:0050897,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.1.16 ko:K01438 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R00669,R09107 RC00064,RC00300 ko00000,ko00001,ko00002,ko01000 - - iECUMN_1333.ECUMN_4488 M20_dimer,Peptidase_M20,Peptidase_M28 k141_34197_3 1279017.AQYJ01000028_gene2190 5.25e-252 699.0 COG0548@1|root,COG1246@1|root,COG0548@2|Bacteria,COG1246@2|Bacteria,1MUUP@1224|Proteobacteria,1RMV5@1236|Gammaproteobacteria,46457@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the acetyltransferase family. ArgA subfamily argA GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1 ko:K14682 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R00259 RC00004,RC00064 ko00000,ko00001,ko00002,ko01000 - - iECP_1309.ECP_2830,iLF82_1304.LF82_0116,iNRG857_1313.NRG857_13920,iYL1228.KPN_03226 AA_kinase,Acetyltransf_1 k141_4548_4 701347.Entcl_2706 1.27e-66 210.0 COG0424@1|root,COG0424@2|Bacteria,1RDA9@1224|Proteobacteria,1S3TQ@1236|Gammaproteobacteria,3X0YD@547|Enterobacter 1236|Gammaproteobacteria D Maf-like protein yceF GO:0003674,GO:0003824,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0047429 - ko:K06287 - - - - ko00000 - - - Maf k141_15182_1 1385935.N836_10600 1.86e-33 125.0 COG0668@1|root,COG0668@2|Bacteria,1G06A@1117|Cyanobacteria 1117|Cyanobacteria M COG0668 Small-conductance mechanosensitive channel - - - - - - - - - - - - MS_channel k141_15182_2 1519464.HY22_03790 8.21e-76 239.0 COG0151@1|root,COG0151@2|Bacteria 2|Bacteria F phosphoribosylamine-glycine ligase activity purD - 6.3.4.13,6.3.5.5 ko:K01945,ko:K01955 ko00230,ko00240,ko00250,ko01100,ko01110,ko01130,map00230,map00240,map00250,map01100,map01110,map01130 M00048,M00051 R00256,R00575,R01395,R04144,R10948,R10949 RC00002,RC00010,RC00043,RC00090,RC00166,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp_3,GARS_A,GARS_C,GARS_N k141_13065_1 1116375.VEJY3_24016 0.0 1216.0 COG0612@1|root,COG0612@2|Bacteria,1RE46@1224|Proteobacteria,1T167@1236|Gammaproteobacteria,1XT9U@135623|Vibrionales 135623|Vibrionales S Belongs to the peptidase M16 family - - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C k141_24913_1 1196031.ALEG01000036_gene3963 2.2e-83 251.0 COG0454@1|root,COG0456@2|Bacteria,1V2FB@1239|Firmicutes,4HFUN@91061|Bacilli,1ZFIM@1386|Bacillus 91061|Bacilli K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases yhfO - - - - - - - - - - - Acetyltransf_1,Acetyltransf_4 k141_37749_1 1453501.JELR01000002_gene1491 1.08e-09 57.8 COG0730@1|root,COG0730@2|Bacteria,1R3V4@1224|Proteobacteria,1RVNC@1236|Gammaproteobacteria,466K2@72275|Alteromonadaceae 1236|Gammaproteobacteria S membrane transporter protein - - - - - - - - - - - - TauE k141_37749_2 1453501.JELR01000002_gene1492 2.02e-18 85.1 COG1913@1|root,COG1913@2|Bacteria,1MY52@1224|Proteobacteria,1RSIP@1236|Gammaproteobacteria,4646U@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF5117) - - - - - - - - - - - - DUF4953,DUF5117 k141_7979_1 1382358.JHVN01000004_gene2658 1.01e-86 258.0 COG2050@1|root,COG2050@2|Bacteria,1V1XV@1239|Firmicutes,4HFUV@91061|Bacilli 91061|Bacilli Q protein possibly involved in aromatic compounds catabolism - - - - - - - - - - - - 4HBT k141_7979_2 997346.HMPREF9374_3897 2.76e-126 377.0 COG1929@1|root,COG1929@2|Bacteria,1TPSI@1239|Firmicutes,4HA91@91061|Bacilli,27BU4@186824|Thermoactinomycetaceae 91061|Bacilli G Glycerate kinase family glxK - 2.7.1.165 ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 - R08572 RC00002,RC00428 ko00000,ko00001,ko01000 - - - Gly_kinase k141_3346_1 218284.CCDN010000001_gene232 5.34e-98 295.0 COG0137@1|root,COG0137@2|Bacteria,1TP3X@1239|Firmicutes,4HA1E@91061|Bacilli,1ZC1P@1386|Bacillus 91061|Bacilli E Belongs to the argininosuccinate synthase family. Type 1 subfamily argG GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 M00029,M00844,M00845 R01954 RC00380,RC00629 ko00000,ko00001,ko00002,ko01000,ko04147 - - iSB619.SA_RS04675 Arginosuc_synth k141_3346_2 218284.CCDN010000001_gene231 3.35e-34 120.0 2DDRJ@1|root,32U1X@2|Bacteria,1VCE7@1239|Firmicutes,4HKC5@91061|Bacilli,1ZI76@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_3346_3 218284.CCDN010000001_gene230 4.29e-24 97.4 28I6D@1|root,2ZAC7@2|Bacteria,1UYC6@1239|Firmicutes,4HFH1@91061|Bacilli,1ZC06@1386|Bacillus 91061|Bacilli S EcsC protein family - - - - - - - - - - - - EcsC k141_37750_1 218284.CCDN010000001_gene1406 1.03e-139 402.0 COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,1TPE2@1239|Firmicutes,4H9WH@91061|Bacilli,1ZCD8@1386|Bacillus 91061|Bacilli P Rhodanese Homology Domain yrkH - - - - - - - - - - - Lactamase_B,Rhodanese k141_4550_2 223926.28805577 1.04e-79 244.0 COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,1RNTY@1236|Gammaproteobacteria,1XTB0@135623|Vibrionales 135623|Vibrionales U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secF - - ko:K03074 ko03060,ko03070,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD_SecF,Sec_GG k141_17620_1 218284.CCDN010000001_gene1950 2.59e-103 308.0 COG2334@1|root,COG2334@2|Bacteria,1TSRC@1239|Firmicutes,4HEJ3@91061|Bacilli,1ZEJM@1386|Bacillus 91061|Bacilli S homoserine kinase type II (protein kinase fold) yerI - - - - - - - - - - - APH k141_15184_1 768066.HELO_1018 5.82e-41 150.0 COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,1MV3Z@1224|Proteobacteria,1RMAJ@1236|Gammaproteobacteria,1XHK9@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose hldE - 2.7.1.167,2.7.7.70 ko:K03272 ko00540,ko01100,map00540,map01100 M00064 R05644,R05646 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CTP_transf_like,PfkB k141_7980_1 661478.OP10G_1182 7.13e-84 262.0 COG5274@1|root,COG5274@2|Bacteria 2|Bacteria C heme binding - - 1.13.11.52 ko:K00463 ko00380,ko01100,ko05143,map00380,map01100,map05143 M00038 R00678,R02702,R02909,R03628 RC00356 ko00000,ko00001,ko00002,ko01000 - - - Cyt-b5,FAD_binding_1,IDO,NAD_binding_1 k141_24915_1 1294265.JCM21738_1702 1.11e-106 326.0 COG1277@1|root,COG1277@2|Bacteria,1TRJ8@1239|Firmicutes,4HA9I@91061|Bacilli,1ZCXM@1386|Bacillus 91061|Bacilli S ABC-type transport system involved in multi-copper enzyme maturation permease component - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - - k141_20184_1 218284.CCDN010000001_gene1685 9.33e-86 278.0 COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,4HC3Y@91061|Bacilli,1ZCCY@1386|Bacillus 91061|Bacilli V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family yerP1 - - - - - - - - - - - ACR_tran k141_37751_1 1121374.KB891575_gene802 1.38e-84 254.0 COG1917@1|root,COG1917@2|Bacteria,1N3S2@1224|Proteobacteria 1224|Proteobacteria S Aspartyl/Asparaginyl beta-hydroxylase - - - - - - - - - - - - Asp_Arg_Hydrox k141_33069_1 1279017.AQYJ01000028_gene2279 9.96e-76 245.0 COG0366@1|root,COG0366@2|Bacteria,1Q8Y2@1224|Proteobacteria,1RQV0@1236|Gammaproteobacteria,464WX@72275|Alteromonadaceae 1236|Gammaproteobacteria G Alpha amylase, catalytic domain - - - - - - - - - - - - Alpha-amylase,Alpha-amylase_C,Malt_amylase_C k141_33069_2 1279017.AQYJ01000028_gene2280 7.11e-273 768.0 COG1501@1|root,COG1501@2|Bacteria,1MWNJ@1224|Proteobacteria,1RMJ9@1236|Gammaproteobacteria,465UA@72275|Alteromonadaceae 1236|Gammaproteobacteria G Belongs to the glycosyl hydrolase 31 family malZ GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016758,GO:0033825,GO:0046527 2.4.1.161,3.2.1.177,3.2.1.20 ko:K01187,ko:K01811,ko:K18820 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00028,R00801,R00802,R06087,R06088 RC00028,RC00049,RC00077 ko00000,ko00001,ko01000 - GH31 - CBM_20,DUF4968,DUF5110,Gal_mutarotas_2,Glyco_hydro_31,PA14 k141_28196_2 1279017.AQYJ01000028_gene2440 5.67e-74 228.0 COG0625@1|root,COG0625@2|Bacteria,1RHSK@1224|Proteobacteria,1RR26@1236|Gammaproteobacteria,46C95@72275|Alteromonadaceae 1236|Gammaproteobacteria O Glutathione S-transferase, N-terminal domain yibF GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C,GST_C_2,GST_N_3 k141_17622_1 713586.KB900536_gene2603 2.55e-71 229.0 COG0403@1|root,COG0403@2|Bacteria,1MVC1@1224|Proteobacteria,1RPGZ@1236|Gammaproteobacteria,1WWD2@135613|Chromatiales 135613|Chromatiales E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor gcvPA - 1.4.4.2 ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 - R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko01000 - - - GDC-P k141_37752_1 42565.FP66_04675 4.04e-114 335.0 COG1289@1|root,COG1289@2|Bacteria,1MUWE@1224|Proteobacteria,1RNFT@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Membrane yeeA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - FUSC,FUSC_2 k141_13068_1 1294265.JCM21738_3693 4.92e-179 504.0 COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,4HAT6@91061|Bacilli,1ZB62@1386|Bacillus 91061|Bacilli C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits atpD - 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_N k141_2117_1 1453501.JELR01000001_gene1917 1.06e-66 220.0 COG1386@1|root,COG1386@2|Bacteria,1PUA6@1224|Proteobacteria,1RNXE@1236|Gammaproteobacteria,4649H@72275|Alteromonadaceae 1236|Gammaproteobacteria D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves scpB - - ko:K06024 - - - - ko00000,ko03036 - - - SMC_ScpB k141_2117_2 1279017.AQYJ01000026_gene361 1.87e-170 480.0 COG1187@1|root,COG1187@2|Bacteria,1MUCE@1224|Proteobacteria,1RQU0@1236|Gammaproteobacteria,463YU@72275|Alteromonadaceae 1236|Gammaproteobacteria J Belongs to the pseudouridine synthase RsuA family rluB GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.22 ko:K06178 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 k141_2117_3 1453501.JELR01000001_gene1919 7.64e-38 136.0 COG3832@1|root,COG3832@2|Bacteria,1RDMX@1224|Proteobacteria,1S914@1236|Gammaproteobacteria,46DJU@72275|Alteromonadaceae 1236|Gammaproteobacteria S Polyketide cyclase / dehydrase and lipid transport - - - - - - - - - - - - GyrI-like,Polyketide_cyc2 k141_29616_1 1042377.AFPJ01000052_gene1541 9.17e-80 251.0 COG0836@1|root,COG0836@2|Bacteria,1MV39@1224|Proteobacteria,1RNQI@1236|Gammaproteobacteria,4644C@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the mannose-6-phosphate isomerase type 2 family cpsB GO:0000271,GO:0003674,GO:0003824,GO:0004475,GO:0005975,GO:0005976,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0008152,GO:0008905,GO:0008928,GO:0009058,GO:0009059,GO:0009242,GO:0009628,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016772,GO:0016779,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046377,GO:0050896,GO:0070568,GO:0071704,GO:1901135,GO:1901137,GO:1901576 2.7.7.13,5.3.1.8 ko:K00971,ko:K16011 ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025 M00114,M00361,M00362 R00885,R01819 RC00002,RC00376 ko00000,ko00001,ko00002,ko01000 - - iE2348C_1286.E2348C_2191,iEC042_1314.EC042_2286,iECIAI1_1343.ECIAI1_2124,iECO26_1355.ECO26_2960,iECSE_1348.ECSE_2323,iECW_1372.ECW_m2206,iEKO11_1354.EKO11_1746,iEcE24377_1341.EcE24377A_2342,iLF82_1304.LF82_0345,iNRG857_1313.NRG857_10420,iWFL_1372.ECW_m2206 MannoseP_isomer,NTP_transferase k141_17623_1 218284.CCDN010000001_gene1779 7.61e-118 347.0 COG3852@1|root,COG3852@2|Bacteria,1TRH0@1239|Firmicutes,4HD4A@91061|Bacilli,1ZDWU@1386|Bacillus 91061|Bacilli T COG0642 Signal transduction histidine kinase kinC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 ko:K07698 ko02020,map02020 M00485 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS,PAS_3,PAS_9 k141_30496_1 1128427.KB904821_gene1362 2.5e-07 57.8 COG2931@1|root,COG3209@1|root,COG4733@1|root,COG2931@2|Bacteria,COG3209@2|Bacteria,COG4733@2|Bacteria,1G0ZC@1117|Cyanobacteria,1H8KD@1150|Oscillatoriales 1117|Cyanobacteria Q PFAM Hemolysin-type calcium-binding repeat (2 copies) - - - - - - - - - - - - Chlam_PMP,DUF4114,He_PIG,fn3 k141_21140_1 218284.CCDN010000006_gene3536 1.14e-142 412.0 COG1785@1|root,COG1785@2|Bacteria,1TQCI@1239|Firmicutes,4HA27@91061|Bacilli,1ZB3J@1386|Bacillus 91061|Bacilli P Belongs to the alkaline phosphatase family phoB - 3.1.3.1 ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 M00126 R02135,R04620 RC00017 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 - - - Alk_phosphatase k141_34332_1 223926.28806263 5.08e-102 303.0 COG0010@1|root,COG0010@2|Bacteria,1NCRN@1224|Proteobacteria,1RNKI@1236|Gammaproteobacteria,1XV0K@135623|Vibrionales 135623|Vibrionales E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide hutG GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016813,GO:0019439,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0052803,GO:0052805,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.3.8 ko:K01479 ko00340,ko01100,map00340,map01100 M00045 R02285 RC00221,RC00681 ko00000,ko00001,ko00002,ko01000 - - - Arginase k141_34332_2 674977.VMC_18580 2.22e-151 429.0 2BYAF@1|root,2ZWH8@2|Bacteria,1RBZ8@1224|Proteobacteria,1S3VD@1236|Gammaproteobacteria,1Y29R@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF3581) SO4011 - - - - - - - - - - - DUF3581 k141_34332_3 1116375.VEJY3_06145 5.64e-228 629.0 COG0435@1|root,COG0435@2|Bacteria,1MV50@1224|Proteobacteria,1RMTI@1236|Gammaproteobacteria,1XZY0@135623|Vibrionales 135623|Vibrionales O Glutathione S-transferase, C-terminal domain - - 1.8.5.7 ko:K07393 - - - - ko00000,ko01000 - - - GST_C_2,GST_N_2 k141_34332_4 1116375.VEJY3_06140 2.9e-187 521.0 COG3384@1|root,COG3384@2|Bacteria,1MXJZ@1224|Proteobacteria,1RR5P@1236|Gammaproteobacteria,1XY0Y@135623|Vibrionales 135623|Vibrionales S Catalytic LigB subunit of aromatic ring-opening dioxygenase - - - ko:K15777 ko00965,map00965 - R08836 RC00387 ko00000,ko00001,ko01000 - - - LigB k141_34332_5 1116375.VEJY3_06135 3.39e-199 553.0 COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,1SWNZ@1236|Gammaproteobacteria,1Y0D9@135623|Vibrionales 135623|Vibrionales K LysR substrate binding domain - - - - - - - - - - - - LysR_substrate k141_34332_6 1116375.VEJY3_06130 3.68e-88 261.0 COG2020@1|root,COG2020@2|Bacteria,1MZ7S@1224|Proteobacteria,1S8Y4@1236|Gammaproteobacteria,1XX3I@135623|Vibrionales 135623|Vibrionales O Phospholipid methyltransferase - - - - - - - - - - - - PEMT k141_3349_1 1232437.KL662006_gene4384 5.68e-21 87.8 2E9PG@1|root,333VW@2|Bacteria,1NEU7@1224|Proteobacteria,42ZPQ@68525|delta/epsilon subdivisions,2WV1S@28221|Deltaproteobacteria,2MNDN@213118|Desulfobacterales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k141_20185_1 218284.CCDN010000006_gene3661 1.54e-156 449.0 COG1932@1|root,COG1932@2|Bacteria,1TP6Y@1239|Firmicutes,4HATT@91061|Bacilli,1ZB9N@1386|Bacillus 91061|Bacilli E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine serC GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 M00020,M00124 R04173,R05085 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_5 k141_24917_2 218284.CCDN010000002_gene2939 3.55e-75 233.0 COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,4HA4E@91061|Bacilli,1ZB72@1386|Bacillus 91061|Bacilli P Belongs to the ABC transporter superfamily - - - ko:K02031 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - ABC_tran,oligo_HPY k141_29617_1 1042377.AFPJ01000032_gene2830 5.08e-134 393.0 COG2959@1|root,COG2959@2|Bacteria,1MY3A@1224|Proteobacteria,1RNJY@1236|Gammaproteobacteria,467C6@72275|Alteromonadaceae 1236|Gammaproteobacteria H enzyme of heme biosynthesis hemX - 2.1.1.107,4.2.1.75 ko:K02496,ko:K13543 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R03165,R03194 RC00003,RC00871,RC01861 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b3803,iBWG_1329.BWG_3482,iECDH1ME8569_1439.ECDH1ME8569_3682,iECUMN_1333.ECUMN_4327,iECs_1301.ECs4733,iEcDH1_1363.EcDH1_4176,iJO1366.b3803,iJR904.b3803,iPC815.YPO3851,iUMN146_1321.UM146_19140,iY75_1357.Y75_RS18060,iZ_1308.Z5317 HemX k141_13069_1 218284.CCDN010000001_gene1309 1.67e-52 178.0 COG0531@1|root,COG0531@2|Bacteria,1V1FX@1239|Firmicutes,4HFZN@91061|Bacilli,1ZFS6@1386|Bacillus 91061|Bacilli E Spore germination protein gerKB - - - - - - - - - - - Spore_permease k141_13069_2 218284.CCDN010000001_gene1310 7.03e-104 312.0 28N49@1|root,2ZB9S@2|Bacteria,1UY59@1239|Firmicutes,4HBU7@91061|Bacilli,1ZG1M@1386|Bacillus 91061|Bacilli S Spore germination B3/ GerAC like, C-terminal gerKC - - - - - - - - - - - Spore_GerAC k141_21141_2 218284.CCDN010000001_gene674 2.62e-103 307.0 2CHZZ@1|root,32S6Y@2|Bacteria,1VA01@1239|Firmicutes,4IJSI@91061|Bacilli,1ZJVW@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_4555_1 218284.CCDN010000001_gene24 1.68e-189 560.0 COG1196@1|root,COG1196@2|Bacteria,1TPJV@1239|Firmicutes,4HB89@91061|Bacilli,1ZAWM@1386|Bacillus 91061|Bacilli D Required for chromosome condensation and partitioning smc GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K03529 - - - - ko00000,ko03036 - - - SMC_N,SMC_hinge k141_29619_1 1042377.AFPJ01000036_gene1137 2.44e-111 347.0 COG1629@1|root,COG1629@2|Bacteria,1MVSG@1224|Proteobacteria,1RS33@1236|Gammaproteobacteria,46A68@72275|Alteromonadaceae 1236|Gammaproteobacteria P Carboxypeptidase regulatory-like domain - - - - - - - - - - - - CarboxypepD_reg k141_30497_2 1116375.VEJY3_19276 4.81e-135 384.0 COG2197@1|root,COG2197@2|Bacteria,1NQH7@1224|Proteobacteria,1RNXI@1236|Gammaproteobacteria,1XVRY@135623|Vibrionales 135623|Vibrionales K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - - - - - - - - - - GerE,Response_reg k141_34333_1 1279017.AQYJ01000025_gene632 1.87e-61 193.0 2CIH2@1|root,2ZTG0@2|Bacteria,1RIN4@1224|Proteobacteria,1S8NA@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Putative lumazine-binding - - - - - - - - - - - - Lumazine_bd_2 k141_17626_1 1294265.JCM21738_3792 1.06e-165 481.0 COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TPJ8@1239|Firmicutes,4HA8X@91061|Bacilli,1ZC48@1386|Bacillus 91061|Bacilli G phosphotransferase system ptsG GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.1.199 ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 M00809 R02738 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.13,4.A.1.1.14,4.A.1.1.9 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC k141_13070_1 218284.CCDN010000001_gene275 7.63e-111 327.0 COG1473@1|root,COG1473@2|Bacteria,1TQ7R@1239|Firmicutes,4HB6M@91061|Bacilli,1ZB9M@1386|Bacillus 91061|Bacilli S amidohydrolase amhX - - ko:K14665 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 k141_2119_2 218284.CCDN010000001_gene528 6.64e-136 390.0 COG0266@1|root,COG0266@2|Bacteria,1TPM9@1239|Firmicutes,4H9Q7@91061|Bacilli,1ZCC9@1386|Bacillus 91061|Bacilli L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates fpg - 3.2.2.23,4.2.99.18 ko:K10563 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Fapy_DNA_glyco,H2TH,zf-FPG_IleRS k141_37756_1 1042377.AFPJ01000004_gene340 1.26e-86 264.0 COG3833@1|root,COG3833@2|Bacteria,1R28D@1224|Proteobacteria,1T5IQ@1236|Gammaproteobacteria,46DBX@72275|Alteromonadaceae 1236|Gammaproteobacteria G Binding-protein-dependent transport system inner membrane component - - - ko:K15772 ko02010,map02010 M00491 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.16,3.A.1.1.2 - - BPD_transp_1 k141_31620_1 1035308.AQYY01000001_gene1469 1.4e-44 158.0 COG0676@1|root,COG0676@2|Bacteria 2|Bacteria G glucose-6-phosphate 1-epimerase activity yeaD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716 4.2.1.9,5.1.3.15 ko:K01687,ko:K01792 ko00010,ko00290,ko00770,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00010,map00290,map00770,map01100,map01110,map01120,map01130,map01210,map01230 M00019,M00570 R01209,R02739,R04441,R05070 RC00468,RC00563,RC01714 ko00000,ko00001,ko00002,ko01000 - - - Aldose_epim k141_31620_2 1453501.JELR01000001_gene3133 1.76e-161 460.0 COG0598@1|root,COG0598@2|Bacteria,1MW8W@1224|Proteobacteria,1RRTZ@1236|Gammaproteobacteria,464S0@72275|Alteromonadaceae 1236|Gammaproteobacteria P CorA-like Mg2+ transporter protein zntB GO:0000041,GO:0003674,GO:0005215,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0015562,GO:0016020,GO:0016021,GO:0022857,GO:0022883,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046583,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662 - ko:K16074 - - - - ko00000,ko02000 1.A.35.4 - - CorA k141_31620_3 930166.CD58_08860 6.96e-80 248.0 COG1946@1|root,COG1946@2|Bacteria,1NAQM@1224|Proteobacteria,1S29R@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Acyl-CoA thioesterase - - - - - - - - - - - - 4HBT_3 k141_24951_2 1279017.AQYJ01000029_gene3584 1.03e-91 273.0 COG1595@1|root,COG1595@2|Bacteria,1RHRR@1224|Proteobacteria,1S2UD@1236|Gammaproteobacteria,46820@72275|Alteromonadaceae 1236|Gammaproteobacteria K Belongs to the sigma-70 factor family. ECF subfamily sigY - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4,Sigma70_r4_2 k141_24951_3 160488.PP_2738 2.41e-33 121.0 COG3631@1|root,COG3631@2|Bacteria,1MZS5@1224|Proteobacteria,1S8VN@1236|Gammaproteobacteria,1YYRS@136845|Pseudomonas putida group 1236|Gammaproteobacteria S SnoaL-like domain - - - - - - - - - - - - SnoaL_2 k141_24951_4 1279017.AQYJ01000029_gene3586 2.11e-93 280.0 COG0300@1|root,COG0300@2|Bacteria,1R735@1224|Proteobacteria,1RSHH@1236|Gammaproteobacteria,467CS@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) sdh - - - - - - - - - - - adh_short k141_36478_1 1294265.JCM21738_4708 5.43e-140 411.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,1ZBIW@1386|Bacillus 91061|Bacilli V COG1132 ABC-type multidrug transport system, ATPase and permease components yknV GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702 - ko:K02021,ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21 - - ABC_membrane,ABC_tran k141_21166_1 218284.CCDN010000008_gene4214 1.47e-184 539.0 COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,4HA1S@91061|Bacilli,1ZAYY@1386|Bacillus 91061|Bacilli D Belongs to the FtsK SpoIIIE SftA family sftA - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_SpoIIIE,Ftsk_gamma k141_33097_1 861299.J421_2748 3.48e-175 520.0 COG0178@1|root,COG0178@2|Bacteria,1ZTDJ@142182|Gemmatimonadetes 142182|Gemmatimonadetes L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate uvrA - - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran k141_17656_1 1116375.VEJY3_13900 0.0 993.0 COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,1RMS9@1236|Gammaproteobacteria,1XSPJ@135623|Vibrionales 135623|Vibrionales L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate uvrA GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009380,GO:0009381,GO:0009987,GO:0016787,GO:0016788,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran k141_17656_2 1116375.VEJY3_13895 5.56e-125 360.0 COG1210@1|root,COG1210@2|Bacteria,1MV5F@1224|Proteobacteria,1RNDX@1236|Gammaproteobacteria,1XT3R@135623|Vibrionales 135623|Vibrionales M UTP--glucose-1-phosphate uridylyltransferase galU - 2.7.7.9 ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 M00129,M00361,M00362,M00549 R00289 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase k141_2148_1 223926.28809596 2.45e-74 231.0 COG0673@1|root,COG0673@2|Bacteria,1MZIG@1224|Proteobacteria,1RS5T@1236|Gammaproteobacteria,1XU2H@135623|Vibrionales 135623|Vibrionales S dehydrogenases and related proteins - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C k141_34354_1 1279017.AQYJ01000028_gene2418 3.03e-97 291.0 COG1716@1|root,COG1716@2|Bacteria,1REM9@1224|Proteobacteria,1S46E@1236|Gammaproteobacteria 1236|Gammaproteobacteria T COG1716 FOG FHA domain - - - - - - - - - - - - FHA k141_4580_1 218284.CCDN010000001_gene280 1.1e-143 410.0 COG0697@1|root,COG0697@2|Bacteria,1V2GJ@1239|Firmicutes,4HV8D@91061|Bacilli,1ZRP6@1386|Bacillus 91061|Bacilli EG EamA-like transporter family - - - - - - - - - - - - EamA k141_8006_1 1279017.AQYJ01000028_gene2280 2.17e-178 522.0 COG1501@1|root,COG1501@2|Bacteria,1MWNJ@1224|Proteobacteria,1RMJ9@1236|Gammaproteobacteria,465UA@72275|Alteromonadaceae 1236|Gammaproteobacteria G Belongs to the glycosyl hydrolase 31 family malZ GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016758,GO:0033825,GO:0046527 2.4.1.161,3.2.1.177,3.2.1.20 ko:K01187,ko:K01811,ko:K18820 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00028,R00801,R00802,R06087,R06088 RC00028,RC00049,RC00077 ko00000,ko00001,ko01000 - GH31 - CBM_20,DUF4968,DUF5110,Gal_mutarotas_2,Glyco_hydro_31,PA14 k141_8006_2 1042377.AFPJ01000004_gene352 1.14e-280 787.0 COG0366@1|root,COG0366@2|Bacteria,1MU90@1224|Proteobacteria,1RQ1S@1236|Gammaproteobacteria,464Q7@72275|Alteromonadaceae 1236|Gammaproteobacteria G Belongs to the glycosyl hydrolase 13 family - - 3.2.1.135 ko:K21575 - - - - ko00000,ko01000 - GH13 - Alpha-amylase,Cyc-maltodext_C,Cyc-maltodext_N k141_8006_3 1042377.AFPJ01000004_gene364 2.76e-122 361.0 COG2211@1|root,COG2211@2|Bacteria,1MX4Z@1224|Proteobacteria,1RRNW@1236|Gammaproteobacteria,464IV@72275|Alteromonadaceae 1236|Gammaproteobacteria G COG0477 Permeases of the major facilitator superfamily - - - ko:K16211 - - - - ko00000,ko02000 2.A.2.6 - - MFS_1,MFS_2 k141_24952_1 1294265.JCM21738_4181 1.15e-120 350.0 COG1234@1|root,COG1234@2|Bacteria,1TRGP@1239|Firmicutes,4HABM@91061|Bacilli,1ZC3J@1386|Bacillus 91061|Bacilli S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA rnz GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0042802,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 3.1.26.11 ko:K00784 ko03013,map03013 - - - ko00000,ko00001,ko01000,ko03016 - - - Lactamase_B,Lactamase_B_2 k141_17657_1 981383.AEWH01000042_gene1599 4.13e-45 152.0 COG2320@1|root,COG2320@2|Bacteria,1V3IB@1239|Firmicutes,4HH5X@91061|Bacilli 91061|Bacilli K GrpB protein - - - - - - - - - - - - GrpB k141_36479_1 441769.ABFU01000050_gene3979 2.14e-53 169.0 COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,4HAE2@91061|Bacilli,1ZBCR@1386|Bacillus 91061|Bacilli C Electron transfer flavoprotein etfA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 - ko:K03522 - - - - ko00000,ko04147 - - - ETF,ETF_alpha k141_31639_1 1116375.VEJY3_19411 8.91e-33 120.0 COG0583@1|root,COG0583@2|Bacteria,1MX2A@1224|Proteobacteria,1RPHN@1236|Gammaproteobacteria,1Y264@135623|Vibrionales 135623|Vibrionales K COG0583 Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_31639_2 1116375.VEJY3_19416 1.1e-76 231.0 COG3090@1|root,COG3090@2|Bacteria,1RB5V@1224|Proteobacteria,1TJ4V@1236|Gammaproteobacteria,1Y0IN@135623|Vibrionales 135623|Vibrionales G COG3090 TRAP-type C4-dicarboxylate transport system, small permease component - - - - - - - - - - - - DctQ k141_31639_3 1116375.VEJY3_19421 1.04e-51 174.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,1RXSY@1236|Gammaproteobacteria,1XZX7@135623|Vibrionales 135623|Vibrionales G COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - - - - - - - - - - DctM k141_10589_1 1122599.AUGR01000017_gene2920 1.69e-09 58.2 COG4240@1|root,COG4240@2|Bacteria,1QUTA@1224|Proteobacteria,1T23W@1236|Gammaproteobacteria,1XHZP@135619|Oceanospirillales 135619|Oceanospirillales S COG4240 Predicted kinase - - 2.7.1.31 ko:K15918 ko00260,ko00561,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00561,map00630,map01100,map01110,map01130,map01200 M00532 R01514 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - ArgK,PRK k141_24953_1 1307436.PBF_03135 3.1e-59 201.0 COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,4H9T9@91061|Bacilli,1ZBH0@1386|Bacillus 91061|Bacilli S YhgE Pip N-terminal domain protein yhgE - - ko:K01421 - - - - ko00000 - - - ABC2_membrane_3,DUF3533 k141_34355_1 1280001.BAOA01000033_gene2227 6.5e-21 84.0 2DMHR@1|root,32RMI@2|Bacteria,1QK1W@1224|Proteobacteria,1TI4F@1236|Gammaproteobacteria,1XYCQ@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_36480_1 218284.CCDN010000007_gene3957 6.08e-108 320.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HA2A@91061|Bacilli,1ZBG3@1386|Bacillus 91061|Bacilli I acyl-CoA dehydrogenase mmgC - - ko:K18244 - - - - ko00000,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_17658_1 42565.FP66_06275 6.37e-45 147.0 COG0799@1|root,COG0799@2|Bacteria,1MZEF@1224|Proteobacteria,1S8W3@1236|Gammaproteobacteria,1XKG3@135619|Oceanospirillales 135619|Oceanospirillales J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation rsfS - - ko:K09710 - - - - ko00000,ko03009 - - - RsfS k141_17658_2 42565.FP66_06280 2.34e-27 105.0 COG1057@1|root,COG1057@2|Bacteria,1RD0J@1224|Proteobacteria,1RP00@1236|Gammaproteobacteria,1XK5V@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) nadD - 2.7.7.18 ko:K00969 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like k141_29652_1 1347369.CCAD010000076_gene3341 3.26e-44 160.0 COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4H9ZK@91061|Bacilli,1ZCFC@1386|Bacillus 91061|Bacilli S ABC transporter - - - - - - - - - - - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn k141_29652_2 935837.JAEK01000007_gene3204 1.38e-30 113.0 2A6RZ@1|root,30VK4@2|Bacteria,1V5GS@1239|Firmicutes,4HHIA@91061|Bacilli,1ZG9Z@1386|Bacillus 91061|Bacilli S Predicted integral membrane protein (DUF2269) - - - - - - - - - - - - DUF2269 k141_4582_1 1279017.AQYJ01000027_gene1855 1.51e-136 421.0 COG0308@1|root,COG0308@2|Bacteria,1PTWJ@1224|Proteobacteria,1RZH5@1236|Gammaproteobacteria,465WC@72275|Alteromonadaceae 1236|Gammaproteobacteria E Peptidase family M1 domain - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_2,ABC2_membrane_4,Peptidase_M1 k141_15201_1 1305836.AXVE01000012_gene117 1.82e-58 186.0 COG4297@1|root,COG4297@2|Bacteria,1V6MJ@1239|Firmicutes,4HJGB@91061|Bacilli,26FAQ@186818|Planococcaceae 91061|Bacilli S Cupin domain yjlB - - - - - - - - - - - Cupin_1,Cupin_2 k141_36813_1 87626.PTD2_03241 1.25e-10 66.2 COG1520@1|root,COG3325@1|root,COG5184@1|root,COG1520@2|Bacteria,COG3325@2|Bacteria,COG5184@2|Bacteria,1QVUK@1224|Proteobacteria,1T2JE@1236|Gammaproteobacteria,2Q5EJ@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria DZ Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - - - - - - - - - - REJ k141_30827_2 1294265.JCM21738_1543 5.05e-15 70.1 29S7W@1|root,30DCD@2|Bacteria,1UB4V@1239|Firmicutes,4IMHF@91061|Bacilli,1ZK5X@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_15455_1 1294265.JCM21738_395 7.16e-60 191.0 COG1426@1|root,COG1426@2|Bacteria,1V1N7@1239|Firmicutes,4HKW3@91061|Bacilli,1ZDC1@1386|Bacillus 91061|Bacilli S protein conserved in bacteria ymfM - - ko:K15539 - - - - ko00000 - - - DUF4115,HTH_25 k141_15455_2 1294265.JCM21738_394 4.58e-161 452.0 28HGR@1|root,2Z7SI@2|Bacteria,1TRXV@1239|Firmicutes,4HA2I@91061|Bacilli,1ZAU1@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3388) ymfK - - - - - - - - - - - DUF3388 k141_36814_1 218284.CCDN010000001_gene669 2.79e-144 425.0 COG0860@1|root,COG3103@1|root,COG3807@1|root,COG0860@2|Bacteria,COG3103@2|Bacteria,COG3807@2|Bacteria,1UYPW@1239|Firmicutes,4HBVT@91061|Bacilli,1ZDI1@1386|Bacillus 91061|Bacilli M COG3103 SH3 domain protein lytH GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - Amidase_3,SH3_3 k141_15456_1 857087.Metme_2224 3.4e-108 351.0 COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,1RMW9@1236|Gammaproteobacteria,1XDIT@135618|Methylococcales 135618|Methylococcales G Glycosyl hydrolase 36 superfamily, catalytic domain - - - ko:K13688 - - - - ko00000,ko01000,ko01003 - GH94,GT84 - Glyco_hydro_36,Glyco_transf_36,Glycoamylase k141_30828_3 1341151.ASZU01000006_gene2884 9.06e-23 92.4 COG3815@1|root,COG3815@2|Bacteria,1VGBP@1239|Firmicutes,4IR7B@91061|Bacilli,27CB4@186824|Thermoactinomycetaceae 91061|Bacilli S Predicted membrane protein (DUF2085) - - - - - - - - - - - - DUF2085 k141_31945_1 218284.CCDN010000004_gene3134 2.35e-168 488.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,1ZBIW@1386|Bacillus 91061|Bacilli V COG1132 ABC-type multidrug transport system, ATPase and permease components yheH GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702 - ko:K18217,ko:K18890 ko02010,map02010 M00635,M00707 - - ko00000,ko00001,ko00002,ko01504,ko02000 3.A.1,3.A.1.106.13,3.A.1.106.5 - - ABC_membrane,ABC_tran k141_31947_1 223926.28809094 8.41e-87 278.0 COG2267@1|root,COG2267@2|Bacteria,1QUH9@1224|Proteobacteria,1T1YS@1236|Gammaproteobacteria,1XU7S@135623|Vibrionales 135623|Vibrionales I Bacterial virulence factor lipase N-terminal - GO:0003674,GO:0003824,GO:0006629,GO:0008150,GO:0008152,GO:0009056,GO:0016042,GO:0016298,GO:0016787,GO:0016788,GO:0044238,GO:0071704,GO:1901575 - - - - - - - - - - Lipase_bact_N k141_30832_2 218284.CCDN010000002_gene2052 1.8e-133 382.0 COG2966@1|root,COG2966@2|Bacteria,1TSE8@1239|Firmicutes,4HBW1@91061|Bacilli,1ZBTT@1386|Bacillus 91061|Bacilli S Putative threonine/serine exporter yjjP - - - - - - - - - - - ThrE k141_31948_1 1279017.AQYJ01000027_gene1695 1.94e-115 349.0 COG4642@1|root,COG4642@2|Bacteria,1P07C@1224|Proteobacteria,1S26V@1236|Gammaproteobacteria,4682N@72275|Alteromonadaceae 1236|Gammaproteobacteria S Peptidase C13 family - - - - - - - - - - - - MORN,Peptidase_C13 k141_31949_1 1449049.JONW01000002_gene2435 5.37e-30 111.0 COG3865@1|root,COG3865@2|Bacteria,1N7IY@1224|Proteobacteria,2U993@28211|Alphaproteobacteria,2KH91@204458|Caulobacterales 204458|Caulobacterales S 3-demethylubiquinone-9 3-methyltransferase - - - - - - - - - - - - 3-dmu-9_3-mt k141_31949_2 1117315.AHCA01000001_gene2137 1.94e-18 79.7 COG3795@1|root,COG3795@2|Bacteria,1N32U@1224|Proteobacteria,1S82G@1236|Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - YCII k141_36817_1 218284.CCDN010000002_gene2803 2.85e-110 330.0 COG1114@1|root,COG1114@2|Bacteria,1TQIS@1239|Firmicutes,4HAKA@91061|Bacilli,1ZAST@1386|Bacillus 91061|Bacilli E Component of the transport system for branched-chain amino acids brnQ - - ko:K03311 - - - - ko00000 2.A.26 - - Branch_AA_trans k141_31951_1 1131730.BAVI_10331 1.71e-109 323.0 COG3239@1|root,COG3239@2|Bacteria,1TP3B@1239|Firmicutes,4H9TS@91061|Bacilli,1ZAYJ@1386|Bacillus 91061|Bacilli I fatty acid desaturase des - 1.14.19.23,1.14.19.45 ko:K10255 ko02020,map02020 - - - ko00000,ko00001,ko01000,ko01004 - - - FA_desaturase k141_36819_2 1396858.Q666_02840 2.12e-152 434.0 COG0627@1|root,COG0627@2|Bacteria,1MUID@1224|Proteobacteria,1RMR3@1236|Gammaproteobacteria,46528@72275|Alteromonadaceae 1236|Gammaproteobacteria S Serine hydrolase involved in the detoxification of formaldehyde yeiG - 3.1.2.12 ko:K01070 ko00680,ko01120,ko01200,map00680,map01120,map01200 - R00527 RC00167,RC00320 ko00000,ko00001,ko01000 - CE1 - Esterase k141_36819_3 1278307.KB906987_gene4215 9.2e-07 49.7 COG1062@1|root,COG1062@2|Bacteria,1MUK4@1224|Proteobacteria,1RNQ4@1236|Gammaproteobacteria,2QHE2@267894|Psychromonadaceae 1236|Gammaproteobacteria C Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily frmA - 1.1.1.1,1.1.1.284 ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 - R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N k141_36820_1 218284.CCDN010000002_gene2197 1.29e-41 152.0 COG5373@1|root,COG5373@2|Bacteria,1UXZY@1239|Firmicutes,4HEQP@91061|Bacilli,1ZBHN@1386|Bacillus 91061|Bacilli S Predicted membrane protein (DUF2339) - - - - - - - - - - - - DUF2339 k141_36821_1 218284.CCDN010000001_gene1787 3.48e-70 221.0 COG4851@1|root,COG4851@2|Bacteria,1U8WG@1239|Firmicutes,4IIV0@91061|Bacilli,1ZMRB@1386|Bacillus 91061|Bacilli S CamS sex pheromone cAM373 precursor - - - - - - - - - - - - CamS k141_31952_2 675806.VII_002048 1.72e-245 686.0 COG4964@1|root,COG4964@2|Bacteria,1MV8G@1224|Proteobacteria,1RQ4U@1236|Gammaproteobacteria,1XU4G@135623|Vibrionales 135623|Vibrionales U Belongs to the GSP D family - - - ko:K02280 - - - - ko00000,ko02035,ko02044 - - - BON,Secretin,T2SS-T3SS_pil_N k141_31952_3 1051646.VITU9109_21834 1.06e-23 92.8 2AWMU@1|root,31NIJ@2|Bacteria,1QK98@1224|Proteobacteria,1TICP@1236|Gammaproteobacteria,1XYVM@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_31952_4 1348635.BBJY01000008_gene1746 1.26e-52 183.0 COG4961@1|root,COG4961@2|Bacteria,1R58C@1224|Proteobacteria,1S1A4@1236|Gammaproteobacteria,1XWG5@135623|Vibrionales 135623|Vibrionales U Putative Flp pilus-assembly TadE/G-like - - - - - - - - - - - - Tad k141_36823_1 218284.CCDN010000005_gene3334 1.7e-164 481.0 COG0209@1|root,COG0209@2|Bacteria,1TPFH@1239|Firmicutes,4H9X0@91061|Bacilli,1ZANT@1386|Bacillus 91061|Bacilli F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdA - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN k141_36824_1 1294265.JCM21738_3803 1.82e-105 311.0 COG1075@1|root,COG1075@2|Bacteria,1TQFF@1239|Firmicutes,4HDQN@91061|Bacilli,1ZCCU@1386|Bacillus 91061|Bacilli S acetyltransferases and hydrolases with the alpha beta hydrolase fold lipA1 - - - - - - - - - - - DUF676,PGAP1 k141_31954_1 1453501.JELR01000002_gene212 6.58e-07 50.4 COG3300@1|root,COG3300@2|Bacteria,1QUST@1224|Proteobacteria,1S7RZ@1236|Gammaproteobacteria,46877@72275|Alteromonadaceae 1236|Gammaproteobacteria T Bacterial signalling protein N terminal repeat - - - - - - - - - - - - MHYT k141_31954_2 177437.HRM2_33890 6.59e-40 143.0 COG1278@1|root,COG3326@1|root,COG1278@2|Bacteria,COG3326@2|Bacteria,1N6YM@1224|Proteobacteria,42TQY@68525|delta/epsilon subdivisions,2WQIP@28221|Deltaproteobacteria,2MNNV@213118|Desulfobacterales 28221|Deltaproteobacteria K Protein of unknown function (DUF1294) - - - - - - - - - - - - CSD,DUF1294 k141_31954_3 1279017.AQYJ01000023_gene3096 7.68e-24 95.9 2EIS4@1|root,33CHF@2|Bacteria,1NI1D@1224|Proteobacteria,1SGX0@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_31954_4 1279017.AQYJ01000023_gene3095 8.43e-164 462.0 COG0788@1|root,COG0788@2|Bacteria,1MVCF@1224|Proteobacteria,1RN6Q@1236|Gammaproteobacteria,465BY@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) purU GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006753,GO:0006760,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008864,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009256,GO:0009257,GO:0009259,GO:0009260,GO:0009396,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0034641,GO:0034654,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.5.1.10 ko:K01433 ko00630,ko00670,map00630,map00670 - R00944 RC00026,RC00111 ko00000,ko00001,ko01000 - - iSDY_1059.SDY_1284 ACT,Formyl_trans_N k141_31955_1 1282360.ABAC460_01725 1.17e-21 94.7 COG0558@1|root,COG0558@2|Bacteria,1MZ70@1224|Proteobacteria 1224|Proteobacteria I CDP-alcohol phosphatidyltransferase - - 2.7.8.5 ko:K00995 ko00564,ko01100,map00564,map01100 - R01801 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 - - - CDP-OH_P_transf k141_31957_1 935836.JAEL01000019_gene924 2.01e-17 82.4 COG0457@1|root,COG0457@2|Bacteria,1UBH2@1239|Firmicutes,4HB47@91061|Bacilli,1ZD40@1386|Bacillus 91061|Bacilli S COG0457 FOG TPR repeat yvcD - - - - - - - - - - - HTH_psq,TPR_16,TPR_19,TPR_2,TPR_8 k141_31957_2 1294265.JCM21738_1657 2.36e-83 253.0 COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,4HA4N@91061|Bacilli,1ZBDJ@1386|Bacillus 91061|Bacilli C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family trxB - 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Pyr_redox_2 k141_36831_1 1307436.PBF_04110 2.1e-30 127.0 2DPC7@1|root,331GW@2|Bacteria,1VF6Y@1239|Firmicutes,4HPGW@91061|Bacilli,1ZHDU@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_31959_1 218284.CCDN010000002_gene2297 2.7e-63 197.0 COG1349@1|root,COG1349@2|Bacteria,1V2NI@1239|Firmicutes,4HG3I@91061|Bacilli,1ZGG8@1386|Bacillus 91061|Bacilli K COG1349 Transcriptional regulators of sugar metabolism ycnK - - ko:K21601 - - - - ko00000,ko03000 - - - HTH_DeoR,NosL k141_31960_2 218284.CCDN010000001_gene1085 4.75e-75 232.0 COG0252@1|root,COG0252@2|Bacteria,1TPP9@1239|Firmicutes,4H9YJ@91061|Bacilli,1ZAZT@1386|Bacillus 91061|Bacilli EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D ansB - 3.5.1.1 ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 - R00485 RC00010,RC02798 ko00000,ko00001,ko01000 - - - Asparaginase k141_36833_1 333138.LQ50_10280 8.31e-12 65.9 COG1408@1|root,COG1408@2|Bacteria,1V494@1239|Firmicutes,4HH1B@91061|Bacilli,1ZBFW@1386|Bacillus 91061|Bacilli S Calcineurin-like phosphoesterase superfamily domain ypbG - - ko:K07098 - - - - ko00000 - - - Metallophos,Metallophos_2 k141_31962_1 1278073.MYSTI_03136 1.16e-47 167.0 COG2114@1|root,COG2114@2|Bacteria,1MV1V@1224|Proteobacteria,43AYF@68525|delta/epsilon subdivisions,2X6CS@28221|Deltaproteobacteria 28221|Deltaproteobacteria T Adenylyl- / guanylyl cyclase, catalytic domain - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_cyc k141_36835_1 1294265.JCM21738_2145 8.11e-83 253.0 2BZRV@1|root,2Z8AV@2|Bacteria,1UX40@1239|Firmicutes,4HAVP@91061|Bacilli,1ZDM4@1386|Bacillus 91061|Bacilli S Nuclease-related domain - - - - - - - - - - - - NERD k141_31964_1 218284.CCDN010000007_gene3984 2.06e-73 223.0 COG1971@1|root,COG1971@2|Bacteria,1V4QK@1239|Firmicutes,4HH7C@91061|Bacilli,1ZFK0@1386|Bacillus 91061|Bacilli P Probably functions as a manganese efflux pump mntP - - - - - - - - - - - Mntp k141_36837_1 935836.JAEL01000018_gene1074 8.4e-46 162.0 COG1835@1|root,COG1835@2|Bacteria,1UHQ0@1239|Firmicutes,4IS5X@91061|Bacilli,1ZERD@1386|Bacillus 91061|Bacilli I Acyltransferase family - - - - - - - - - - - - Acyl_transf_3 k141_31965_1 441769.ABFU01000003_gene2313 5.78e-65 206.0 COG0030@1|root,COG0030@2|Bacteria,1TP9W@1239|Firmicutes,4HA4R@91061|Bacilli,1ZBZX@1386|Bacillus 91061|Bacilli J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits ksgA GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 ko:K02528 - - R10716 RC00003,RC03257 ko00000,ko01000,ko03009 - - - RrnaAD k141_36839_1 218284.CCDN010000002_gene1994 2.23e-63 197.0 2EAXM@1|root,334YP@2|Bacteria,1VIHS@1239|Firmicutes,4HR0C@91061|Bacilli,1ZJ0E@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2892) - - - - - - - - - - - - DUF2892 k141_36843_1 218284.CCDN010000001_gene1795 3.3e-67 215.0 COG0174@1|root,COG0174@2|Bacteria,1TNZA@1239|Firmicutes,4HACE@91061|Bacilli,1ZBIQ@1386|Bacillus 91061|Bacilli E glutamine synthetase glnA GO:0003674,GO:0005488,GO:0005515,GO:0006082,GO:0006355,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0006808,GO:0007154,GO:0007584,GO:0008134,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009605,GO:0009719,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016053,GO:0016597,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043392,GO:0043436,GO:0043562,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0045892,GO:0045934,GO:0046394,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051098,GO:0051100,GO:0051101,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0061984,GO:0065007,GO:0065009,GO:0070406,GO:0070887,GO:0071310,GO:0071417,GO:0071495,GO:0071496,GO:0071704,GO:0080090,GO:0090293,GO:0090295,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901698,GO:1901699,GO:1902679,GO:1903506,GO:1903507,GO:1904796,GO:1904797,GO:2000112,GO:2000113,GO:2000677,GO:2000678,GO:2001141 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C,Gln-synt_N k141_36843_2 218284.CCDN010000001_gene1796 2.53e-23 92.4 COG0789@1|root,COG0789@2|Bacteria,1V6JE@1239|Firmicutes,4HKM6@91061|Bacilli,1ZH1F@1386|Bacillus 91061|Bacilli K transcriptional glnR GO:0003674,GO:0005488,GO:0005515,GO:0006082,GO:0006355,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016053,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031326,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903506,GO:2000112,GO:2001141 - ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000,ko03000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - MerR_1 k141_36845_1 674977.VMC_38440 2.39e-45 150.0 28I53@1|root,2Z88I@2|Bacteria,1NE5N@1224|Proteobacteria,1RP35@1236|Gammaproteobacteria,1Y03I@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF3750) - - - - - - - - - - - - DUF3750 k141_31966_1 1232683.ADIMK_2589 9.29e-68 224.0 COG3119@1|root,COG3119@2|Bacteria,1MV92@1224|Proteobacteria,1RPDE@1236|Gammaproteobacteria,464V5@72275|Alteromonadaceae 1236|Gammaproteobacteria P Sulfatase atsA - 3.1.6.1 ko:K01130 ko00140,ko00600,map00140,map00600 - R03980,R04856 RC00128,RC00231 ko00000,ko00001,ko01000 - - - Sulfatase k141_31966_2 400668.Mmwyl1_3148 2.22e-138 401.0 COG0583@1|root,COG0583@2|Bacteria,1PEF2@1224|Proteobacteria,1RS7V@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_31966_3 400668.Mmwyl1_3147 6.06e-246 691.0 COG3203@1|root,COG3203@2|Bacteria,1MXEB@1224|Proteobacteria,1RZNZ@1236|Gammaproteobacteria,1XKDT@135619|Oceanospirillales 135619|Oceanospirillales M Protein of unknown function (DUF1302) - - - - - - - - - - - - DUF1302 k141_31966_4 1396858.Q666_09130 1.83e-13 70.9 28H52@1|root,2ZADT@2|Bacteria,1R8NH@1224|Proteobacteria,1RQUB@1236|Gammaproteobacteria,46DG6@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF1329) - - - - - - - - - - - - DUF1329 k141_36848_1 223926.28807199 3.68e-223 639.0 COG1025@1|root,COG1025@2|Bacteria,1QTVC@1224|Proteobacteria,1T1IG@1236|Gammaproteobacteria,1XT1Q@135623|Vibrionales 135623|Vibrionales O Belongs to the peptidase M16 family ptrA - - - - - - - - - - - Peptidase_M16,Peptidase_M16_C,Peptidase_M16_M k141_31970_1 1279017.AQYJ01000027_gene1540 7.74e-108 324.0 COG3520@1|root,COG3520@2|Bacteria,1MWVS@1224|Proteobacteria,1RQD5@1236|Gammaproteobacteria,4687C@72275|Alteromonadaceae 1236|Gammaproteobacteria S Type VI secretion, TssG - - - ko:K11895 ko02025,map02025 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - T6SS_TssG k141_2383_2 377629.TERTU_1738 3.63e-65 211.0 COG2515@1|root,COG2515@2|Bacteria,1MVYF@1224|Proteobacteria,1RMYP@1236|Gammaproteobacteria,2PMHS@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria E Pyridoxal-phosphate dependent enzyme - - 4.4.1.15 ko:K05396 ko00270,map00270 - R01874 RC00382 ko00000,ko00001,ko01000 - - - PALP k141_10704_2 311403.Arad_0504 5.09e-28 108.0 COG2020@1|root,COG2020@2|Bacteria,1MZ7S@1224|Proteobacteria,2UBYC@28211|Alphaproteobacteria,4BC19@82115|Rhizobiaceae 28211|Alphaproteobacteria O Phospholipid methyltransferase - - - - - - - - - - - - PEMT k141_10704_3 259536.Psyc_1604 7.49e-145 419.0 COG2515@1|root,COG2515@2|Bacteria,1MVYF@1224|Proteobacteria,1RMYP@1236|Gammaproteobacteria,3NK9X@468|Moraxellaceae 1236|Gammaproteobacteria E Pyridoxal-phosphate dependent enzyme - - 4.4.1.15,4.4.1.25 ko:K05396,ko:K17950 ko00270,map00270 - R01874,R07634 RC00382,RC01784 ko00000,ko00001,ko01000 - - - PALP k141_10704_4 1279017.AQYJ01000027_gene1645 2.02e-69 215.0 COG1670@1|root,COG1670@2|Bacteria,1RCX2@1224|Proteobacteria,1S42B@1236|Gammaproteobacteria,466TJ@72275|Alteromonadaceae 1236|Gammaproteobacteria J Acetyltransferase (GNAT) domain - - 2.3.1.128 ko:K03790 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 k141_23790_1 227377.CBU_0490 9.76e-28 115.0 COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,1MYXV@1224|Proteobacteria,1T7PM@1236|Gammaproteobacteria,1JFN8@118969|Legionellales 118969|Legionellales L Helix-hairpin-helix domain - - - ko:K02347 - - - - ko00000,ko03400 - - - DNA_pol_B_thumb,HHH_8 k141_33296_2 1116375.VEJY3_16181 3e-125 358.0 COG0352@1|root,COG0352@2|Bacteria,1RDSU@1224|Proteobacteria,1S6QS@1236|Gammaproteobacteria,1XUU6@135623|Vibrionales 135623|Vibrionales H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) thiE - 2.5.1.3 ko:K00788 ko00730,ko01100,map00730,map01100 M00127 R03223,R10712 RC00224,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 - - - TMP-TENI k141_33296_3 1116375.VEJY3_16186 1.99e-43 148.0 COG2145@1|root,COG2145@2|Bacteria,1MVES@1224|Proteobacteria,1RRAE@1236|Gammaproteobacteria,1XSM9@135623|Vibrionales 135623|Vibrionales H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ) thiM - 2.7.1.50 ko:K00878 ko00730,ko01100,map00730,map01100 M00127 R04448 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - HK k141_16647_2 1042377.AFPJ01000028_gene2259 2.02e-158 447.0 COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,1RPMP@1236|Gammaproteobacteria,466UT@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0545 FKBP-type peptidyl-prolyl cis-trans isomerases 1 mip - 5.2.1.8 ko:K03772,ko:K03773 - - - - ko00000,ko01000,ko03110 - - - FKBP_C,FKBP_N k141_9515_1 1121127.JAFA01000015_gene6355 7.68e-16 72.8 COG0346@1|root,COG0346@2|Bacteria,1RDNZ@1224|Proteobacteria,2WE8D@28216|Betaproteobacteria,1KHNE@119060|Burkholderiaceae 28216|Betaproteobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - Glyoxalase k141_9515_2 1453501.JELR01000002_gene756 6.24e-191 539.0 COG0332@1|root,COG0332@2|Bacteria,1NAGY@1224|Proteobacteria,1RN1T@1236|Gammaproteobacteria,466PH@72275|Alteromonadaceae 1236|Gammaproteobacteria I 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal - - 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACP_syn_III,ACP_syn_III_C,Haem_oxygenas_2,ketoacyl-synt k141_9515_3 1453501.JELR01000002_gene755 1.31e-112 328.0 COG0332@1|root,COG0332@2|Bacteria 2|Bacteria I beta-ketoacyl-acyl-carrier-protein synthase III activity - - 2.3.1.180,2.3.1.41 ko:K00647,ko:K00648 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00082,M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119,R10707 RC00004,RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACP_syn_III,ACP_syn_III_C,Haem_oxygenas_2 k141_9515_4 1453501.JELR01000002_gene754 1.28e-173 489.0 2CIYT@1|root,2Z7R8@2|Bacteria,1Q6MN@1224|Proteobacteria,1S0UE@1236|Gammaproteobacteria,46BXB@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_4763_2 218284.CCDN010000002_gene2889 5.16e-106 313.0 COG0609@1|root,COG0609@2|Bacteria,1TP13@1239|Firmicutes,4HA75@91061|Bacilli,1ZC7Z@1386|Bacillus 91061|Bacilli P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily fhuB - - ko:K02015 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - FecCD k141_27352_2 218284.CCDN010000002_gene2413 9.54e-13 65.9 COG2808@1|root,COG2808@2|Bacteria,1TXED@1239|Firmicutes,4HEZS@91061|Bacilli,1ZDPR@1386|Bacillus 91061|Bacilli K Transcriptional regulator paiB - - ko:K07734 - - - - ko00000,ko03000 - - - FMN_bind_2 k141_3576_1 1453501.JELR01000005_gene1596 1.82e-102 317.0 COG0366@1|root,COG0366@2|Bacteria,1NUIZ@1224|Proteobacteria,1RPMQ@1236|Gammaproteobacteria,465DG@72275|Alteromonadaceae 1236|Gammaproteobacteria G Alpha amylase, catalytic domain - - 2.4.1.19 ko:K00701 ko00500,map00500 - R11260 - ko00000,ko00001,ko01000 - CBM20,GH13 - Alpha-amylase k141_15464_1 218284.CCDN010000001_gene787 4.56e-96 300.0 COG0768@1|root,COG0768@2|Bacteria,1TQHY@1239|Firmicutes,4HAFX@91061|Bacilli,1ZBJM@1386|Bacillus 91061|Bacilli M penicillin-binding protein pbpH - - ko:K21465 ko00550,map00550 - - - ko00000,ko00001,ko01011 - - - PBP_dimer,Transpeptidase k141_28539_2 218284.CCDN010000001_gene1807 1.35e-105 322.0 COG0323@1|root,COG0323@2|Bacteria,1TPGK@1239|Firmicutes,4HB34@91061|Bacilli,1ZB9X@1386|Bacillus 91061|Bacilli L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex mutL GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032300,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1990391 - ko:K03572 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - DNA_mis_repair,HATPase_c_3,MutL_C k141_34486_1 218284.CCDN010000001_gene1950 2.14e-70 223.0 COG2334@1|root,COG2334@2|Bacteria,1TSRC@1239|Firmicutes,4HEJ3@91061|Bacilli,1ZEJM@1386|Bacillus 91061|Bacilli S homoserine kinase type II (protein kinase fold) yerI - - - - - - - - - - - APH k141_34486_2 218284.CCDN010000001_gene1949 8.96e-19 77.8 2B1JX@1|root,31U1A@2|Bacteria,1UCU4@1239|Firmicutes,4IPAA@91061|Bacilli,1ZPMC@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_29728_1 218284.CCDN010000001_gene58 4.35e-129 396.0 COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,4HAEY@91061|Bacilli,1ZCEM@1386|Bacillus 91061|Bacilli F Belongs to the CarB family carB GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS k141_1193_1 218284.CCDN010000001_gene1313 3.79e-76 234.0 COG1309@1|root,COG1309@2|Bacteria,1VFD2@1239|Firmicutes,4HM3Q@91061|Bacilli,1ZIA5@1386|Bacillus 91061|Bacilli K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N k141_1193_2 218284.CCDN010000001_gene1312 5.07e-54 171.0 COG2076@1|root,COG2076@2|Bacteria,1VA2G@1239|Firmicutes,4HKGV@91061|Bacilli,1ZHW4@1386|Bacillus 91061|Bacilli P Multidrug resistance protein ykkC - - ko:K11741,ko:K18924 - M00712 - - ko00000,ko00002,ko02000 2.A.7.1,2.A.7.1.5 - - Multi_Drug_Res k141_21412_2 1243664.CAVL020000054_gene3013 2.89e-55 184.0 2E9AZ@1|root,333IU@2|Bacteria,1VGQF@1239|Firmicutes,4HQBT@91061|Bacilli,1ZH89@1386|Bacillus 91061|Bacilli S Phage tail protein - - - - - - - - - - - - Sipho_tail k141_28540_1 997296.PB1_09427 1.19e-121 374.0 COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,4HAW9@91061|Bacilli,1ZARC@1386|Bacillus 91061|Bacilli L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate uvrA - - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran k141_11895_1 218284.CCDN010000001_gene995 2.07e-98 290.0 COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4H9WY@91061|Bacilli,1ZB2E@1386|Bacillus 91061|Bacilli E COG1126 ABC-type polar amino acid transport system, ATPase component artM - 3.6.3.21 ko:K02028 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran k141_21413_1 105559.Nwat_3075 3.22e-24 103.0 COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,1RQ8B@1236|Gammaproteobacteria,1WXE6@135613|Chromatiales 135613|Chromatiales T signal transduction histidine kinase - - - - - - - - - - - - HAMP,HATPase_c,HisKA,PAS_4,PAS_8 k141_1194_1 1157637.KB892103_gene1611 1.63e-05 46.6 COG0383@1|root,COG0383@2|Bacteria,2GM02@201174|Actinobacteria 201174|Actinobacteria G PFAM Glycoside hydrolase, family 38 - - 3.2.1.170,3.2.1.24 ko:K01191,ko:K15524 ko00511,map00511 - - - ko00000,ko00001,ko01000,ko04131 - GH38 - Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C k141_1194_2 1121938.AUDY01000009_gene2287 5.91e-79 240.0 COG0395@1|root,COG0395@2|Bacteria,1TRCP@1239|Firmicutes,4HBKE@91061|Bacilli,3NF3V@45667|Halobacillus 91061|Bacilli G Binding-protein-dependent transport system inner membrane component - - - ko:K17246 ko02010,map02010 M00601 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.40 - - BPD_transp_1 k141_36861_1 1453501.JELR01000005_gene1586 0.0 1468.0 COG1629@1|root,COG1629@2|Bacteria,1MWTT@1224|Proteobacteria,1RRQ9@1236|Gammaproteobacteria,464SZ@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - OMP_b-brl_3,Plug,TonB_dep_Rec k141_11_1 1238450.VIBNISOn1_900015 2.26e-39 134.0 COG0789@1|root,COG0789@2|Bacteria,1N9D2@1224|Proteobacteria,1SBR8@1236|Gammaproteobacteria,1XYA6@135623|Vibrionales 135623|Vibrionales K Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - - - - - - - - - - MerR_1 k141_23792_3 935837.JAEK01000012_gene348 3.96e-14 66.2 2EIIR@1|root,33CA1@2|Bacteria,1VMUM@1239|Firmicutes,4HSC6@91061|Bacilli,1ZJ19@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_29729_1 649747.HMPREF0083_02683 1.42e-49 170.0 COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,4HATK@91061|Bacilli,26QJP@186822|Paenibacillaceae 91061|Bacilli I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids fabH - 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACP_syn_III,ACP_syn_III_C k141_34487_2 218284.CCDN010000001_gene630 1.78e-83 252.0 COG0739@1|root,COG0739@2|Bacteria,1TSQI@1239|Firmicutes,4HFC8@91061|Bacilli,1ZFJN@1386|Bacillus 91061|Bacilli M COG0739 Membrane proteins related to metalloendopeptidases spoIVFA - - ko:K06401 - - - - ko00000 - - - Peptidase_M23 k141_7141_1 1196322.A370_03188 5.24e-78 261.0 COG3210@1|root,COG3387@1|root,COG3210@2|Bacteria,COG3387@2|Bacteria,1UHGW@1239|Firmicutes,24S1Q@186801|Clostridia 186801|Clostridia U domain, Protein - - - - - - - - - - - - - k141_13092_2 441769.ABFU01000050_gene3975 7.5e-55 176.0 COG1309@1|root,COG1309@2|Bacteria,1TRSH@1239|Firmicutes,4H9RC@91061|Bacilli,1ZAU5@1386|Bacillus 91061|Bacilli K Transcriptional regulator fadR GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - ko:K13770 - - - - ko00000,ko03000 - - - TetR_C_4,TetR_N k141_12_1 935836.JAEL01000008_gene3889 6.39e-68 212.0 COG0861@1|root,COG0861@2|Bacteria,1TQ09@1239|Firmicutes,4HB99@91061|Bacilli,1ZBYE@1386|Bacillus 91061|Bacilli P Integral membrane protein TerC family - - - - - - - - - - - - TerC k141_15638_2 1367847.JCM7686_0167 2.37e-16 77.4 COG3794@1|root,COG3794@2|Bacteria,1NB0S@1224|Proteobacteria,2UJ9A@28211|Alphaproteobacteria,2PXCU@265|Paracoccus 28211|Alphaproteobacteria C Cupredoxin-like domain mauC GO:0005575,GO:0005623,GO:0042597,GO:0044464 - - - - - - - - - - Copper-bind k141_12021_1 665959.HMPREF1013_01742 4.98e-50 169.0 COG0477@1|root,COG2814@2|Bacteria,1TS6K@1239|Firmicutes,4HB1V@91061|Bacilli,1ZB90@1386|Bacillus 91061|Bacilli EGP COG0477 Permeases of the major facilitator superfamily tetA_3 - - - - - - - - - - - MFS_1,MFS_1_like,Sugar_tr k141_12021_2 1347086.CCBA010000004_gene4429 8.05e-65 208.0 COG0665@1|root,COG0665@2|Bacteria,1TQTF@1239|Firmicutes,4HA0F@91061|Bacilli,1ZBU6@1386|Bacillus 91061|Bacilli E COG0665 Glycine D-amino acid oxidases (deaminating) yurR - 1.4.5.1 ko:K00285 ko00360,map00360 - R01374,R09493 RC00006,RC00025 ko00000,ko00001,ko01000 - - - DAO k141_6143_1 1384057.CD33_08370 1.31e-173 496.0 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4HBS1@91061|Bacilli,3IWI3@400634|Lysinibacillus 91061|Bacilli C 1-pyrroline-5-carboxylate dehydrogenase - - - - - - - - - - - - Aldedh k141_1279_1 411462.DORLON_02987 8.81e-09 57.8 2ED6K@1|root,3373A@2|Bacteria,1VI2S@1239|Firmicutes,24QZV@186801|Clostridia 186801|Clostridia S the current gene model (or a revised gene model) may contain one or more premature stops and or frameshifts - - - - - - - - - - - - - k141_2545_1 218284.CCDN010000004_gene3112 9.66e-59 182.0 COG0011@1|root,COG0011@2|Bacteria,1VBWM@1239|Firmicutes,4HKDU@91061|Bacilli,1ZID1@1386|Bacillus 91061|Bacilli S Thiamine-binding protein M1-594 - - - - - - - - - - - Thiamine_BP k141_2545_2 218284.CCDN010000004_gene3113 6.08e-31 115.0 COG0600@1|root,COG0600@2|Bacteria,1TRFD@1239|Firmicutes,4HARZ@91061|Bacilli,1ZQFJ@1386|Bacillus 91061|Bacilli P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component ytlD1 - - - - - - - - - - - BPD_transp_1 k141_29846_1 1294265.JCM21738_4996 4e-64 204.0 COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1TPH9@1239|Firmicutes,4H9PW@91061|Bacilli,1ZBF9@1386|Bacillus 91061|Bacilli H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate ribBA GO:0003674,GO:0003824,GO:0003933,GO:0003935,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0019238,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.5.4.25,4.1.99.12 ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 M00125,M00840 R00425,R07281 RC00293,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS08945 DHBP_synthase,GTP_cyclohydro2 k141_29846_2 1294265.JCM21738_4995 2.57e-41 141.0 COG0307@1|root,COG0307@2|Bacteria,1V1EP@1239|Firmicutes,4HC7B@91061|Bacilli,1ZBB9@1386|Bacillus 91061|Bacilli H Riboflavin synthase ribE GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9 ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00066 RC00958,RC00960 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS08950,iYO844.BSU23270 Lum_binding k141_18031_1 218284.CCDN010000007_gene3938 1.99e-107 318.0 2C8MW@1|root,2ZCFU@2|Bacteria,1V10H@1239|Firmicutes,4HE3P@91061|Bacilli,1ZCQG@1386|Bacillus 91061|Bacilli S Transcriptional regulator rsfA - - ko:K06314 - - - - ko00000,ko03000 - - - Myb_DNA-bind_6 k141_23886_1 1033734.CAET01000030_gene4029 7.39e-71 224.0 COG0642@1|root,COG2205@2|Bacteria,1TT7F@1239|Firmicutes,4HAPG@91061|Bacilli,1ZDA4@1386|Bacillus 91061|Bacilli T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA k141_1280_1 218284.CCDN010000001_gene1214 1.12e-100 303.0 COG0161@1|root,COG0161@2|Bacteria,1TP9N@1239|Firmicutes,4HD8E@91061|Bacilli,1ZAWS@1386|Bacillus 91061|Bacilli H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family yodT - - - - - - - - - - - Aminotran_3 k141_2546_1 1294265.JCM21738_2703 1.17e-126 372.0 COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,4HB3K@91061|Bacilli,1ZCJR@1386|Bacillus 91061|Bacilli C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes pdhD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyr_redox_2,Pyr_redox_dim k141_36963_1 218284.CCDN010000001_gene1525 2.07e-60 189.0 2EARW@1|root,334U0@2|Bacteria,1VIDH@1239|Firmicutes,4HPDQ@91061|Bacilli,1ZIUM@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_16780_1 1117647.M5M_18335 1.08e-81 255.0 COG0665@1|root,COG0665@2|Bacteria,1MU40@1224|Proteobacteria,1RMJY@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Tryptophan halogenase - - 1.14.19.9 ko:K14266 ko00404,ko01130,map00404,map01130 M00789,M00790 R09570 RC00949 ko00000,ko00001,ko00002,ko01000 - - - Trp_halogenase k141_16780_2 1042377.AFPJ01000008_gene1958 8.42e-147 421.0 COG2850@1|root,COG2850@2|Bacteria,1MUAC@1224|Proteobacteria,1RQQP@1236|Gammaproteobacteria,465RI@72275|Alteromonadaceae 1236|Gammaproteobacteria S Cupin-like domain - - - - - - - - - - - - Cupin_8 k141_10806_1 218284.CCDN010000001_gene1974 8.35e-161 454.0 COG1175@1|root,COG1175@2|Bacteria,1TP1Q@1239|Firmicutes,4HCFJ@91061|Bacilli,1ZDIC@1386|Bacillus 91061|Bacilli G Binding-protein-dependent transport system inner membrane component amyD1 - - ko:K10118 ko02010,map02010 M00196 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.28 - - BPD_transp_1 k141_29847_1 877455.Metbo_1002 2e-48 175.0 COG1950@1|root,arCOG09731@2157|Archaea,2Y2F9@28890|Euryarchaeota,23PAN@183925|Methanobacteria 183925|Methanobacteria S Mycobacterial 4 TMS phage holin, superfamily IV - - - - - - - - - - - - Phage_holin_4_2,Phosphodiest k141_9636_1 379066.GAU_1961 1.61e-75 256.0 COG0653@1|root,COG0653@2|Bacteria,1ZSMK@142182|Gemmatimonadetes 142182|Gemmatimonadetes U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA - - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW k141_21585_1 218284.CCDN010000002_gene2608 2.85e-72 225.0 COG0601@1|root,COG0601@2|Bacteria,1TRW4@1239|Firmicutes,4HEGZ@91061|Bacilli,1ZH5U@1386|Bacillus 91061|Bacilli EP Binding-protein-dependent transport system inner membrane component - - - - - - - - - - - - BPD_transp_1 k141_33404_1 1219076.N646_1153 1.19e-102 315.0 COG0366@1|root,COG0366@2|Bacteria,1MVKX@1224|Proteobacteria,1RQHM@1236|Gammaproteobacteria,1XT2H@135623|Vibrionales 135623|Vibrionales G Belongs to the glycosyl hydrolase 13 family malZ - 3.2.1.20 ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00028,R00801,R00802,R06087,R06088 RC00028,RC00049,RC00077 ko00000,ko00001,ko01000 - GH31 - Alpha-amylase,Alpha-amylase_N,DUF3459,Malt_amylase_C k141_28719_1 377629.TERTU_4288 6.35e-45 161.0 COG0382@1|root,COG0637@1|root,COG0382@2|Bacteria,COG0637@2|Bacteria,1MXCM@1224|Proteobacteria,1RRWB@1236|Gammaproteobacteria,2PPSR@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria H UbiA prenyltransferase family - - - - - - - - - - - - HAD,UbiA k141_8495_1 218284.CCDN010000007_gene3818 7.78e-215 598.0 COG0104@1|root,COG0104@2|Bacteria,1TQ4C@1239|Firmicutes,4H9YT@91061|Bacilli,1ZBF8@1386|Bacillus 91061|Bacilli F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP purA GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 - - - Adenylsucc_synt k141_7276_1 1042377.AFPJ01000014_gene1638 6.16e-85 254.0 COG2135@1|root,COG2135@2|Bacteria,1RCCC@1224|Proteobacteria,1S39B@1236|Gammaproteobacteria,46737@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the SOS response-associated peptidase family - - - - - - - - - - - - SRAP k141_2547_1 333138.LQ50_09640 3.22e-33 117.0 2DIES@1|root,3030J@2|Bacteria,1U9E8@1239|Firmicutes,4IJH6@91061|Bacilli,1ZHZ1@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_28720_1 218284.CCDN010000002_gene2178 2.12e-70 226.0 COG1721@1|root,COG1721@2|Bacteria,1UYJ3@1239|Firmicutes,4HBP9@91061|Bacilli,1ZEFE@1386|Bacillus 91061|Bacilli S von Willebrand factor (vWF) type A domain - - - - - - - - - - - - DUF58 k141_209_1 218284.CCDN010000001_gene254 1.21e-117 340.0 COG1011@1|root,COG1011@2|Bacteria,1V2QW@1239|Firmicutes,4HG68@91061|Bacilli,1ZRBT@1386|Bacillus 91061|Bacilli S HAD-hyrolase-like - - - ko:K07025 - - - - ko00000 - - - HAD_2 k141_23887_2 1294265.JCM21738_4046 7.43e-74 226.0 COG3879@1|root,COG3879@2|Bacteria,1V2J7@1239|Firmicutes,4HG14@91061|Bacilli,1ZDER@1386|Bacillus 91061|Bacilli S protein conserved in bacteria ylxX GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - - - - - - - - - - DUF881 k141_12024_1 674977.VMC_12830 2.91e-150 441.0 COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,1RMWP@1236|Gammaproteobacteria,1XSX1@135623|Vibrionales 135623|Vibrionales G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate tkt - 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C,Transketolase_N k141_32195_2 945543.VIBR0546_02494 0.0 1453.0 COG1002@1|root,COG1002@2|Bacteria,1MWRH@1224|Proteobacteria,1RRRA@1236|Gammaproteobacteria,1XVUP@135623|Vibrionales 135623|Vibrionales V COG1002 Type II restriction enzyme, methylase subunits - - - - - - - - - - - - N6_Mtase k141_32195_3 945543.VIBR0546_02499 0.0 1204.0 COG1061@1|root,COG1061@2|Bacteria,1PPCG@1224|Proteobacteria,1RPSB@1236|Gammaproteobacteria,1XWBI@135623|Vibrionales 135623|Vibrionales L helicase - - - - - - - - - - - - Helicase_C,ResIII k141_1299_1 218284.CCDN010000001_gene598 3.36e-138 394.0 COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4H9WY@91061|Bacilli,1ZB2E@1386|Bacillus 91061|Bacilli E COG1126 ABC-type polar amino acid transport system, ATPase component glnQ_2 - 3.6.3.21 ko:K02028 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran k141_1299_2 218284.CCDN010000001_gene597 4.36e-130 372.0 COG0765@1|root,COG0765@2|Bacteria,1TS6X@1239|Firmicutes,4HC03@91061|Bacilli,1ZCI9@1386|Bacillus 91061|Bacilli E Binding-protein-dependent transport system inner membrane component - - - ko:K02029 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 k141_12042_1 218284.CCDN010000006_gene3671 3.53e-49 167.0 COG2021@1|root,COG2021@2|Bacteria,1TQSV@1239|Firmicutes,4HBNC@91061|Bacilli,1ZEVF@1386|Bacillus 91061|Bacilli E Belongs to the AB hydrolase superfamily. MetX family metXA GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 ko:K00641 ko00270,ko01100,ko01130,map00270,map01100,map01130 - R01776 RC00004,RC00041 ko00000,ko00001,ko01000 - - - Abhydrolase_1 k141_9656_1 935836.JAEL01000085_gene4660 1.04e-38 141.0 COG1388@1|root,COG1388@2|Bacteria,1V8A5@1239|Firmicutes,4HIV2@91061|Bacilli,1ZG8Q@1386|Bacillus 91061|Bacilli M Lysin motif ypbE - - - - - - - - - - - LysM k141_35784_1 1453501.JELR01000002_gene1118 2.85e-155 449.0 COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,1RMH1@1236|Gammaproteobacteria,46553@72275|Alteromonadaceae 1236|Gammaproteobacteria U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins yidC GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0031224,GO:0031226,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051205,GO:0051234,GO:0051259,GO:0051260,GO:0051641,GO:0061024,GO:0065003,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150 - ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 - - 60KD_IMP,YidC_periplas k141_25084_2 1453501.JELR01000001_gene2064 4.83e-153 441.0 COG0697@1|root,COG0697@2|Bacteria,1MYHQ@1224|Proteobacteria,1S4AM@1236|Gammaproteobacteria,467NP@72275|Alteromonadaceae 1236|Gammaproteobacteria EG EamA-like transporter family - - - - - - - - - - - - EamA k141_231_1 796606.BMMGA3_05775 3.83e-16 77.0 COG0564@1|root,COG0564@2|Bacteria,1TPCM@1239|Firmicutes,4HBG2@91061|Bacilli,1ZC3M@1386|Bacillus 91061|Bacilli J Responsible for synthesis of pseudouridine from uracil rluD GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 ko:K06180 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 k141_231_2 218284.CCDN010000001_gene65 7.78e-82 244.0 COG0597@1|root,COG0597@2|Bacteria,1VA9R@1239|Firmicutes,4HIR4@91061|Bacilli,1ZGBF@1386|Bacillus 91061|Bacilli MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins lspA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.4.23.36 ko:K03101 ko03060,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_A8 k141_13267_1 42565.FP66_05225 6.86e-75 232.0 COG4927@1|root,COG4927@2|Bacteria,1NKHP@1224|Proteobacteria 1224|Proteobacteria S Acyl-coenzyme A 6-aminopenicillanic acid acyl-transferase - - - ko:K19200 ko00311,ko01100,ko01130,map00311,map01100,map01130 - - - ko00000,ko00001,ko01002 - - - AAT k141_4908_1 1255043.TVNIR_2274 5.11e-73 246.0 COG1002@1|root,COG2890@1|root,COG1002@2|Bacteria,COG2890@2|Bacteria,1NM9N@1224|Proteobacteria,1RRTM@1236|Gammaproteobacteria 1236|Gammaproteobacteria V Type II restriction enzyme, methylase subunits - - - - - - - - - - - - N6_Mtase k141_8512_2 240302.BN982_04021 2.2e-66 202.0 COG2163@1|root,COG2163@2|Bacteria,1VEPA@1239|Firmicutes,4HJQF@91061|Bacilli,3NEZZ@45667|Halobacillus 91061|Bacilli J COG2163 Ribosomal protein L14E L6E L27E - - - - - - - - - - - - KOW k141_19154_1 1042377.AFPJ01000029_gene552 1.22e-22 96.3 COG0642@1|root,COG2205@2|Bacteria,1N17V@1224|Proteobacteria,1RNFK@1236|Gammaproteobacteria,4647A@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0642 Signal transduction histidine kinase - - 2.7.13.3 ko:K07641 ko02020,map02020 M00449 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA k141_19154_2 1453501.JELR01000005_gene1767 1.57e-65 204.0 COG0745@1|root,COG0745@2|Bacteria,1MVCB@1224|Proteobacteria,1RM87@1236|Gammaproteobacteria,465DT@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain chvI GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042802,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - ko:K02483,ko:K07663 ko02020,map02020 M00449 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C k141_3762_1 574376.BAMA_04145 1.8e-93 285.0 COG0592@1|root,COG0592@2|Bacteria,1U7RA@1239|Firmicutes,4HARM@91061|Bacilli,1ZE26@1386|Bacillus 91061|Bacilli L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria - - 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3 k141_20325_1 218284.CCDN010000001_gene1787 1.53e-97 294.0 COG4851@1|root,COG4851@2|Bacteria,1U8WG@1239|Firmicutes,4IIV0@91061|Bacilli,1ZMRB@1386|Bacillus 91061|Bacilli S CamS sex pheromone cAM373 precursor - - - - - - - - - - - - CamS k141_34650_2 218284.CCDN010000005_gene3489 3.63e-153 435.0 COG0561@1|root,COG0561@2|Bacteria,1TR16@1239|Firmicutes,4HCZ6@91061|Bacilli,1ZCPY@1386|Bacillus 91061|Bacilli S hydrolases of the HAD superfamily yxeH - - - - - - - - - - - Hydrolase_3 k141_34650_3 218284.CCDN010000001_gene1739 8.61e-79 242.0 COG0596@1|root,COG0596@2|Bacteria,1TPEW@1239|Firmicutes,4HC6M@91061|Bacilli,1ZE3I@1386|Bacillus 91061|Bacilli S Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_1 k141_7301_1 218284.CCDN010000006_gene3604 2.92e-97 288.0 COG0745@1|root,COG0745@2|Bacteria,1TS8Z@1239|Firmicutes,4HC86@91061|Bacilli,1ZB3W@1386|Bacillus 91061|Bacilli KT COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - - - - - - - - - - Response_reg,Trans_reg_C k141_28741_1 1116375.VEJY3_12300 1.78e-251 693.0 COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,1RNIY@1236|Gammaproteobacteria,1XTR5@135623|Vibrionales 135623|Vibrionales E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine csdA GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769 2.8.1.7,4.4.1.16 ko:K01766,ko:K11717 ko00450,ko01100,map00450,map01100 - R03599,R11528 RC00961,RC01789,RC02313 ko00000,ko00001,ko01000 - - - Aminotran_5 k141_28741_2 1116375.VEJY3_12295 5.73e-134 380.0 COG0693@1|root,COG0693@2|Bacteria,1N7T2@1224|Proteobacteria,1RSBI@1236|Gammaproteobacteria,1XV1A@135623|Vibrionales 135623|Vibrionales S monophosphate biosynthesis enzyme yajL - 3.5.1.124 ko:K03152 - - - - ko00000,ko01000,ko01002 - - - DJ-1_PfpI k141_26358_1 1294265.JCM21738_1946 3.69e-106 308.0 COG0589@1|root,COG0589@2|Bacteria,1VH3X@1239|Firmicutes,4HNXN@91061|Bacilli,1ZCYJ@1386|Bacillus 91061|Bacilli T Universal stress protein nhaX - - - - - - - - - - - Usp k141_23905_1 223926.28805050 1.1e-130 381.0 COG1249@1|root,COG1249@2|Bacteria,1MU2Z@1224|Proteobacteria,1RMC0@1236|Gammaproteobacteria,1XTC6@135623|Vibrionales 135623|Vibrionales C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family gor - 1.8.1.7 ko:K00383 ko00480,ko04918,map00480,map04918 - R00094,R00115 RC00011 ko00000,ko00001,ko01000 - - - Pyr_redox_2,Pyr_redox_dim k141_23905_2 1116375.VEJY3_00270 1.08e-205 568.0 COG2961@1|root,COG2961@2|Bacteria,1MWGA@1224|Proteobacteria,1RNI1@1236|Gammaproteobacteria,1XSBI@135623|Vibrionales 135623|Vibrionales H Specifically methylates the adenine in position 2030 of 23S rRNA rlmJ - 2.1.1.266 ko:K07115 - - - - ko00000,ko01000,ko03009 - - - RsmJ k141_23905_4 1116375.VEJY3_00275 0.0 1180.0 COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,1RMAH@1236|Gammaproteobacteria,1XTEV@135623|Vibrionales 135623|Vibrionales E COG0339 Zn-dependent oligopeptidases prlC - 3.4.24.70 ko:K01414 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M3 k141_25086_1 1328313.DS2_07098 8.09e-26 107.0 COG2273@1|root,COG2273@2|Bacteria,1NFHX@1224|Proteobacteria,1RRPK@1236|Gammaproteobacteria,464WR@72275|Alteromonadaceae 1236|Gammaproteobacteria G Glycosyl hydrolases family 16 bglA - - - - - - - - - - - CBM_6,DUF5011,Glyco_hydro_16,Malectin k141_2569_1 218284.CCDN010000002_gene2909 6.59e-270 757.0 COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HA0V@91061|Bacilli,1ZBTK@1386|Bacillus 91061|Bacilli O Belongs to the ClpA ClpB family clpE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03697,ko:K04086 - - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,UVR k141_2569_2 1121936.AUHI01000009_gene260 1.23e-40 150.0 COG0753@1|root,COG0753@2|Bacteria,1TPPV@1239|Firmicutes,4H9XQ@91061|Bacilli 91061|Bacilli P Belongs to the catalase family katE - 1.11.1.6 ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 M00532 R00009,R00602,R02670 RC00034,RC00767,RC02141,RC02755 ko00000,ko00001,ko00002,ko01000 - - - Catalase,Catalase-rel,DJ-1_PfpI k141_15654_1 1453501.JELR01000001_gene2411 0.0 1007.0 COG1765@1|root,COG1944@1|root,COG1765@2|Bacteria,COG1944@2|Bacteria,1MV7K@1224|Proteobacteria,1RN47@1236|Gammaproteobacteria,464WG@72275|Alteromonadaceae 1236|Gammaproteobacteria O redox protein, regulator of disulfide bond formation ycaO GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018193,GO:0018197,GO:0018198,GO:0018339,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0047429,GO:0047693,GO:0071704,GO:1901564 - ko:K09136 - - - - ko00000,ko03009 - - - OsmC,YcaO k141_234_1 7739.XP_002614108.1 1.13e-20 89.4 COG1028@1|root,KOG0725@2759|Eukaryota,38BUC@33154|Opisthokonta,3BC34@33208|Metazoa,3D09G@33213|Bilateria,485W0@7711|Chordata 33208|Metazoa Q Enoyl-(Acyl carrier protein) reductase - - 1.5.1.33 ko:K03793 - - - - ko00000,ko01000 - - - adh_short_C2 k141_1301_1 745411.B3C1_10882 6.33e-85 258.0 COG1028@1|root,COG1028@2|Bacteria,1MXTP@1224|Proteobacteria,1RYTY@1236|Gammaproteobacteria,1J6B9@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - 1.1.1.175 ko:K22185 ko00040,map00040 - R01429 RC00066 ko00000,ko00001,ko01000 - - - adh_short_C2 k141_1301_2 266264.Rmet_0832 2.11e-17 83.6 COG1012@1|root,COG1012@2|Bacteria,1MY2V@1224|Proteobacteria,2VH0W@28216|Betaproteobacteria,1K10D@119060|Burkholderiaceae 28216|Betaproteobacteria C Aldehyde dehydrogenase - - 1.2.1.26 ko:K13877 ko00040,ko00053,map00040,map00053 - R00264 RC00080 ko00000,ko00001,ko01000 - - - Aldedh k141_15655_1 1347086.CCBA010000034_gene2725 1.56e-72 241.0 COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,4H9XC@91061|Bacilli,1ZB9E@1386|Bacillus 91061|Bacilli J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain alaS GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DHHA1,tRNA-synt_2c,tRNA_SAD k141_7302_1 1340434.AXVA01000003_gene1857 7.81e-14 69.7 COG0300@1|root,COG0300@2|Bacteria,1V5EI@1239|Firmicutes,4ISWY@91061|Bacilli,1ZS7I@1386|Bacillus 91061|Bacilli S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis ymfI - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 k141_7302_2 1294265.JCM21738_393 2.76e-55 172.0 2E5KP@1|root,330BT@2|Bacteria,1VGM7@1239|Firmicutes,4HNNX@91061|Bacilli,1ZHTB@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3243) ymfJ - - - - - - - - - - - DUF3243 k141_20326_1 279010.BL00475 1.23e-27 107.0 COG3340@1|root,COG3340@2|Bacteria,1V7ZB@1239|Firmicutes,4HIGE@91061|Bacilli,1ZGQX@1386|Bacillus 91061|Bacilli E Belongs to the peptidase S51 family - - 3.4.13.21 ko:K05995 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S51 k141_27471_2 1235279.C772_00907 3.53e-19 85.9 COG2313@1|root,COG2313@2|Bacteria,1TR5J@1239|Firmicutes,4HC38@91061|Bacilli,26CU8@186818|Planococcaceae 91061|Bacilli G Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway psuG - 4.2.1.70 ko:K16329 ko00240,map00240 - R01055 RC00432,RC00433 ko00000,ko00001,ko01000 - - - Indigoidine_A k141_31109_1 118161.KB235922_gene5111 1.49e-24 104.0 COG5361@1|root,COG5361@2|Bacteria,1G4FQ@1117|Cyanobacteria 1117|Cyanobacteria S Protein of unknown function (DUF1254) - - - - - - - - - - - - DUF1214,DUF1254 k141_3764_1 218284.CCDN010000001_gene1171 2.81e-123 360.0 COG3424@1|root,COG3424@2|Bacteria,1TPUK@1239|Firmicutes,4HBHH@91061|Bacilli,1ZC8W@1386|Bacillus 91061|Bacilli Q Naringenin-chalcone synthase bcsA - - ko:K16167 - - - - ko00000,ko01008 - - - Chal_sti_synt_C,Chal_sti_synt_N k141_21608_2 218284.CCDN010000001_gene1339 6.58e-19 85.9 COG0454@1|root,COG0456@2|Bacteria 2|Bacteria K acetyltransferase - - - ko:K18566 ko00332,ko01130,map00332,map01130 - R10745,R10746 RC00004,RC00096 ko00000,ko00001,ko01000 - - - Acetyltransf_1 k141_2570_1 498211.CJA_1363 7.92e-43 161.0 COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,1RNEB@1236|Gammaproteobacteria,1FFZP@10|Cellvibrio 1236|Gammaproteobacteria J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner valS GO:0000287,GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006417,GO:0006418,GO:0006438,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0034248,GO:0034250,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045903,GO:0046483,GO:0046872,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0052689,GO:0060255,GO:0061475,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:2000112 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iECH74115_1262.ECH74115_5779,iECNA114_1301.ECNA114_4481,iECO26_1355.ECO26_5428,iECSP_1301.ECSP_5359,iECs_1301.ECs5235,iG2583_1286.G2583_5088,iJN746.PP_0977,iSBO_1134.SBO_4182,iSSON_1240.SSON_4443,iYL1228.KPN_04663,iZ_1308.Z5870 Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 k141_2570_2 1192868.CAIU01000017_gene2180 0.000562 42.4 COG0454@1|root,COG0456@2|Bacteria,1RIE6@1224|Proteobacteria,2UF5C@28211|Alphaproteobacteria,43JS5@69277|Phyllobacteriaceae 28211|Alphaproteobacteria K FR47-like protein rimI - 2.3.1.128 ko:K03789 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_1,Acetyltransf_10 k141_33414_1 1042377.AFPJ01000022_gene1306 5.18e-81 244.0 COG3707@1|root,COG3707@2|Bacteria,1MXDV@1224|Proteobacteria,1S3YY@1236|Gammaproteobacteria,467KM@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG3707 Response regulator with nasT - - ko:K07183 - - - - ko00000,ko02022 - - - ANTAR,Response_reg k141_19156_1 218284.CCDN010000001_gene227 2.49e-107 317.0 COG0827@1|root,COG0827@2|Bacteria,1TRIQ@1239|Firmicutes,4H9SE@91061|Bacilli,1ZBZ7@1386|Bacillus 91061|Bacilli L DNA methylase ytxK - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_Mtase k141_18056_2 1279017.AQYJ01000024_gene927 1.19e-296 823.0 COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,1RPNE@1236|Gammaproteobacteria,464ZH@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1022 Long-chain acyl-CoA synthetases (AMP-forming) - - - - - - - - - - - - AMP-binding k141_32202_1 1116375.VEJY3_17686 6.91e-300 844.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1XSPS@135623|Vibrionales 135623|Vibrionales U COG0841 Cation multidrug efflux pump acrF - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran k141_32202_2 1116375.VEJY3_17691 0.0 889.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XVGD@135623|Vibrionales 135623|Vibrionales NT methyl-accepting chemotaxis protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - MCPsignal k141_32202_3 223926.28809556 2.13e-74 224.0 COG1186@1|root,COG1186@2|Bacteria,1RH75@1224|Proteobacteria,1S5YQ@1236|Gammaproteobacteria,1XXE0@135623|Vibrionales 135623|Vibrionales J COG1186 Protein chain release factor B yaeJ - - ko:K15034 - - - - ko00000,ko03012 - - - RF-1 k141_32202_4 1116375.VEJY3_17701 7.12e-124 355.0 COG0637@1|root,COG0637@2|Bacteria,1PUMZ@1224|Proteobacteria,1RNJC@1236|Gammaproteobacteria,1XVSG@135623|Vibrionales 135623|Vibrionales S phosphatase phosphohexomutase - - - - - - - - - - - - HAD_2 k141_32202_6 1348635.BBJY01000002_gene3476 3.45e-235 654.0 COG2199@1|root,COG2204@1|root,COG2204@2|Bacteria,COG3706@2|Bacteria,1MXBG@1224|Proteobacteria,1RNJA@1236|Gammaproteobacteria,1XSJA@135623|Vibrionales 135623|Vibrionales T COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - - - - - - - - - - GGDEF,Response_reg k141_29860_1 1453501.JELR01000005_gene1701 7.63e-34 123.0 COG4555@1|root,COG4555@2|Bacteria,1QU2T@1224|Proteobacteria,1RY2V@1236|Gammaproteobacteria,46CK1@72275|Alteromonadaceae 1236|Gammaproteobacteria CP ATPases associated with a variety of cellular activities natA - 3.6.3.7 ko:K09697 ko02010,ko02020,map02010,map02020 M00253 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.115 - - ABC_tran k141_27472_1 1279017.AQYJ01000024_gene1137 1.11e-169 473.0 COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,1RNWR@1236|Gammaproteobacteria,4658G@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG0479 Succinate dehydrogenase fumarate reductase, Fe-S protein subunit sdhB GO:0000104,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0022904,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0051536,GO:0051537,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - e_coli_core.b0724,iAF1260.b0724,iBWG_1329.BWG_0583,iEC042_1314.EC042_0742,iECDH10B_1368.ECDH10B_0791,iECDH1ME8569_1439.ECDH1ME8569_0683,iECUMN_1333.ECUMN_0802,iEcDH1_1363.EcDH1_2911,iJO1366.b0724,iJR904.b0724,iY75_1357.Y75_RS03765 Fer2_3,Fer4_17,Fer4_8 k141_1303_1 1279017.AQYJ01000029_gene3845 4.28e-94 288.0 COG1262@1|root,COG1262@2|Bacteria,1MUNC@1224|Proteobacteria,1RQI4@1236|Gammaproteobacteria,465KE@72275|Alteromonadaceae 1236|Gammaproteobacteria S DinB superfamily egtB - - - - - - - - - - - DinB_2,FGE-sulfatase k141_16804_1 223926.28807581 2.34e-49 164.0 COG1159@1|root,COG1159@2|Bacteria,1MUKT@1224|Proteobacteria,1RN3A@1236|Gammaproteobacteria,1XUB4@135623|Vibrionales 135623|Vibrionales S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism era GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03595 - - - - ko00000,ko03009,ko03029 - - - KH_2,MMR_HSR1 k141_16804_2 674977.VMC_13120 3.82e-154 433.0 COG0571@1|root,COG0571@2|Bacteria,1MUQ6@1224|Proteobacteria,1RN0C@1236|Gammaproteobacteria,1XTPC@135623|Vibrionales 135623|Vibrionales J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism rnc GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 ko:K03685 ko03008,ko05205,map03008,map05205 - - - ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 - - - Ribonucleas_3_3,dsrm k141_16804_3 1116375.VEJY3_13270 4.94e-212 586.0 COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,1RMHI@1236|Gammaproteobacteria,1XUWQ@135623|Vibrionales 135623|Vibrionales U Belongs to the peptidase S26 family lepB - 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24,Peptidase_S26 k141_33529_2 218284.CCDN010000005_gene3167 5.22e-102 325.0 COG4717@1|root,COG4717@2|Bacteria,1TQP3@1239|Firmicutes,4HBCA@91061|Bacilli,1ZDHB@1386|Bacillus 91061|Bacilli L AAA domain yhaN - - - - - - - - - - - AAA_27 k141_16945_1 565045.NOR51B_2437 7.78e-65 218.0 COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,1RMZ8@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate - - 1.1.1.35 ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 M00087 R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000 - - - 3HCDH,3HCDH_N,ECH_1 k141_31213_2 218284.CCDN010000002_gene2775 3.2e-94 288.0 COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,4HBR4@91061|Bacilli,1ZB39@1386|Bacillus 91061|Bacilli JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes dbpA GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 3.6.4.13 ko:K05592 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,DbpA,Helicase_C k141_3879_1 1249627.D779_0533 3.14e-129 386.0 COG0531@1|root,COG0531@2|Bacteria,1QXK2@1224|Proteobacteria,1S18B@1236|Gammaproteobacteria,1WYY6@135613|Chromatiales 135613|Chromatiales E Amino acid permease - - - - - - - - - - - - AA_permease_2 k141_3879_3 1453501.JELR01000002_gene1487 7.25e-91 269.0 COG1225@1|root,COG1225@2|Bacteria,1RER0@1224|Proteobacteria,1S4K1@1236|Gammaproteobacteria,46AJ1@72275|Alteromonadaceae 1236|Gammaproteobacteria O Redoxin - - 1.11.1.15 ko:K03564 - - - - ko00000,ko01000 - - - AhpC-TSA k141_3879_4 941449.dsx2_2345 1.46e-315 863.0 COG0753@1|root,COG0753@2|Bacteria,1MUXZ@1224|Proteobacteria,42MIN@68525|delta/epsilon subdivisions,2WJC5@28221|Deltaproteobacteria,2M91H@213115|Desulfovibrionales 28221|Deltaproteobacteria C Belongs to the catalase family katA - 1.11.1.6 ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 M00532 R00009,R00602,R02670 RC00034,RC00767,RC02141,RC02755 ko00000,ko00001,ko00002,ko01000 - - - Catalase,Catalase-rel k141_3879_5 318167.Sfri_1827 7.23e-56 177.0 COG2303@1|root,COG2303@2|Bacteria,1RH5U@1224|Proteobacteria,1S60X@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - - - - - - - - - - - k141_20404_1 1042377.AFPJ01000032_gene2784 5.91e-67 204.0 COG3450@1|root,COG3450@2|Bacteria,1N3EY@1224|Proteobacteria,1TAJ6@1236|Gammaproteobacteria,46BUM@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF861) - - - ko:K06995 - - - - ko00000 - - - Cupin_3 k141_20404_2 1042377.AFPJ01000043_gene861 4.59e-43 148.0 COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,1RN8W@1236|Gammaproteobacteria,464TQ@72275|Alteromonadaceae 1236|Gammaproteobacteria BQ COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein - - - - - - - - - - - - Hist_deacetyl k141_13397_1 218284.CCDN010000001_gene1128 3.66e-122 352.0 28RMR@1|root,2ZE0H@2|Bacteria,1V1HS@1239|Firmicutes,4HFRG@91061|Bacilli,1ZANV@1386|Bacillus 91061|Bacilli S sporulation protein ypjB - - - - - - - - - - - Spore_YpjB k141_28857_1 1453501.JELR01000002_gene764 1.32e-158 464.0 COG1680@1|root,COG1680@2|Bacteria,1MWHS@1224|Proteobacteria,1RRQF@1236|Gammaproteobacteria 1236|Gammaproteobacteria V COG1680 Beta-lactamase class C and other penicillin binding - - - - - - - - - - - - ASH,Beta-lactamase k141_22882_1 266265.Bxe_A3781 1.08e-13 73.6 COG0472@1|root,COG0472@2|Bacteria,1MWYW@1224|Proteobacteria,2VNAG@28216|Betaproteobacteria,1K2YP@119060|Burkholderiaceae 28216|Betaproteobacteria M PFAM glycosyl transferase family 4 wbiH - - ko:K13007 - - - - ko00000,ko01000,ko01003,ko01005 - - - Glycos_transf_4 k141_19270_1 411466.ACTODO_01675 1.8e-17 82.4 COG4589@1|root,COG4589@2|Bacteria,2GNWK@201174|Actinobacteria,4D37N@85005|Actinomycetales 201174|Actinobacteria S Belongs to the CDS family cdsA GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_1 k141_19270_2 1121015.N789_05735 2.74e-08 56.6 COG0743@1|root,COG0743@2|Bacteria,1MU4G@1224|Proteobacteria,1RNNW@1236|Gammaproteobacteria,1X4I6@135614|Xanthomonadales 135614|Xanthomonadales I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) dxr GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05688 RC01452 ko00000,ko00001,ko00002,ko01000 - - - DXPR_C,DXP_redisom_C,DXP_reductoisom k141_13398_1 1294265.JCM21738_5559 3.39e-72 227.0 COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,4HA7K@91061|Bacilli,1ZDDX@1386|Bacillus 91061|Bacilli F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction ackA - 2.7.2.1 ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00315,R01353 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - Acetate_kinase k141_33530_1 218284.CCDN010000005_gene3374 2.55e-93 284.0 COG1850@1|root,COG1850@2|Bacteria,1TSZQ@1239|Firmicutes,4HBIK@91061|Bacilli,1ZC2J@1386|Bacillus 91061|Bacilli G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P) mtnW GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0009853,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0016984,GO:0043094,GO:0044237 5.3.2.5 ko:K08965 ko00270,ko01100,map00270,map01100 M00034 R07393 RC02421 ko00000,ko00001,ko00002,ko01000 - - - RuBisCO_large,RuBisCO_large_N k141_34739_1 218284.CCDN010000001_gene740 1.8e-115 333.0 COG0274@1|root,COG0274@2|Bacteria,1TPAJ@1239|Firmicutes,4HAAJ@91061|Bacilli,1ZCZ6@1386|Bacillus 91061|Bacilli F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate deoC - 4.1.2.4 ko:K01619 ko00030,map00030 - R01066 RC00436,RC00437 ko00000,ko00001,ko01000 - - - DeoC k141_371_1 1279017.AQYJ01000024_gene993 2.01e-267 741.0 COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,1RMW3@1236|Gammaproteobacteria,463Y1@72275|Alteromonadaceae 1236|Gammaproteobacteria G Belongs to the pyruvate kinase family pykA - 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - PK,PK_C k141_3880_1 1279017.AQYJ01000029_gene3674 4.7e-20 82.0 2E5J4@1|root,330AE@2|Bacteria,1QYT1@1224|Proteobacteria,1T3TB@1236|Gammaproteobacteria,46D5Y@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - Ykof k141_22883_1 218284.CCDN010000002_gene2304 1.06e-118 343.0 COG5522@1|root,COG5522@2|Bacteria,1V57K@1239|Firmicutes,4HHZD@91061|Bacilli,1ZCPD@1386|Bacillus 91061|Bacilli S Integral membrane protein (intg_mem_TP0381) - - - - - - - - - - - - Intg_mem_TP0381 k141_26561_1 1279017.AQYJ01000026_gene246 4.87e-62 201.0 COG2050@1|root,COG2050@2|Bacteria,1RF3N@1224|Proteobacteria,1S82J@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q Thioesterase - - - - - - - - - - - - 4HBT k141_25248_1 1294265.JCM21738_3683 9.85e-97 288.0 COG1404@1|root,COG1404@2|Bacteria,1TPH1@1239|Firmicutes,4HBQH@91061|Bacilli,1ZBS0@1386|Bacillus 91061|Bacilli O Belongs to the peptidase S8 family prtS - 3.4.21.110,3.4.21.96 ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 - - - ko00000,ko00001,ko01000,ko01002,ko03110 - - - FIVAR,Gram_pos_anchor,Inhibitor_I9,PA,Peptidase_S8,YSIRK_signal,fn3_5 k141_35884_2 1501230.ET33_25515 2.99e-06 52.0 COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,4H9WZ@91061|Bacilli,26RWU@186822|Paenibacillaceae 91061|Bacilli D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity ftsZ GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030428,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03531 ko04112,map04112 - - - ko00000,ko00001,ko02048,ko03036,ko04812 - - - FtsZ_C,Tubulin k141_7424_1 1116375.VEJY3_21791 0.0 984.0 COG3391@1|root,COG3391@2|Bacteria,1QUVX@1224|Proteobacteria,1RXP0@1236|Gammaproteobacteria,1XVQR@135623|Vibrionales 135623|Vibrionales S alkaline phosphatase - - - - - - - - - - - - - k141_7424_2 1116375.VEJY3_14420 1.19e-105 305.0 COG1952@1|root,COG1952@2|Bacteria,1RI75@1224|Proteobacteria,1S62H@1236|Gammaproteobacteria,1XU1J@135623|Vibrionales 135623|Vibrionales U One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA secB GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - ko:K03071 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03110 3.A.5 - - SecB k141_7424_3 1116375.VEJY3_14415 3.13e-91 268.0 COG0607@1|root,COG0607@2|Bacteria,1MZ83@1224|Proteobacteria,1S8ZI@1236|Gammaproteobacteria,1XWWT@135623|Vibrionales 135623|Vibrionales P rhodanese-related sulfurtransferase yibN - - - - - - - - - - - Rhodanese k141_7424_4 223926.28807839 1.28e-146 425.0 COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,1RMJE@1236|Gammaproteobacteria,1XTMH@135623|Vibrionales 135623|Vibrionales G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate gpmI GO:0003674,GO:0003824,GO:0004619,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.4.2.12 ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000 - - - Metalloenzyme,Phosphodiest,iPGM_N k141_13399_1 1121938.AUDY01000011_gene665 7.42e-61 199.0 COG0189@1|root,COG0189@2|Bacteria,1UY8Q@1239|Firmicutes,4HBXG@91061|Bacilli 91061|Bacilli HJ YheC/D like ATP-grasp yheD7 - - - - - - - - - - - ATPgrasp_YheCD k141_27548_1 1129374.AJE_07131 2.36e-95 291.0 COG0648@1|root,COG0648@2|Bacteria,1R6X2@1224|Proteobacteria,1RSJ8@1236|Gammaproteobacteria,465V6@72275|Alteromonadaceae 1236|Gammaproteobacteria L Domain of unknown function (DUF4862) - - - - - - - - - - - - DUF4862 k141_19271_1 1532557.JL37_09165 8.28e-58 187.0 COG2846@1|root,COG2846@2|Bacteria,1MVCQ@1224|Proteobacteria,2VJ5Z@28216|Betaproteobacteria,3T4A7@506|Alcaligenaceae 28216|Betaproteobacteria D Di-iron-containing protein involved in the repair of iron-sulfur clusters ytfE - - ko:K07322 - - - - ko00000 - - - Hemerythrin,ScdA_N k141_3881_1 1294265.JCM21738_3593 6.73e-05 42.7 COG0847@1|root,COG0847@2|Bacteria,1V4Q9@1239|Firmicutes,4HFXA@91061|Bacilli,1ZF2J@1386|Bacillus 91061|Bacilli L Exonuclease - - 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - RNase_T k141_3881_2 665959.HMPREF1013_01576 6.12e-38 144.0 COG2905@1|root,COG2905@2|Bacteria,1TQFI@1239|Firmicutes,4HCIW@91061|Bacilli,1ZCEI@1386|Bacillus 91061|Bacilli T Putative nucleotidyltransferase substrate binding domain - - - ko:K07182 - - - - ko00000 - - - CBS,DUF294,DUF294_C,cNMP_binding k141_33531_1 218284.CCDN010000001_gene95 3.18e-61 190.0 2DSU9@1|root,33HF9@2|Bacteria,1VIQ9@1239|Firmicutes,4HPSB@91061|Bacilli,1ZG8K@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3397) - - - - - - - - - - - - DUF3397 k141_26562_1 1336241.JAEB01000014_gene1978 2.21e-15 76.6 COG0603@1|root,COG0603@2|Bacteria,1TP4Z@1239|Firmicutes,2497A@186801|Clostridia,25VE2@186806|Eubacteriaceae 186801|Clostridia F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) queC - 6.3.4.20 ko:K06920 ko00790,ko01100,map00790,map01100 - R09978 RC00959 ko00000,ko00001,ko01000,ko03016 - - - QueC k141_26562_2 1380386.JIAW01000004_gene75 5.61e-12 67.0 COG2159@1|root,COG2159@2|Bacteria,2GMQY@201174|Actinobacteria 201174|Actinobacteria S amidohydrolase - - - ko:K07045 - - - - ko00000 - - - Amidohydro_2 k141_9758_1 218284.CCDN010000001_gene1162 4.81e-72 226.0 COG0116@1|root,COG0116@2|Bacteria,1TP0X@1239|Firmicutes,4HBKY@91061|Bacilli,1ZBJB@1386|Bacillus 91061|Bacilli L Belongs to the methyltransferase superfamily ypsC GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 - ko:K07444 - - - - ko00000,ko01000 - - - THUMP,UPF0020 k141_13400_1 1294265.JCM21738_1998 4.36e-84 251.0 COG1284@1|root,COG1284@2|Bacteria,1V3MX@1239|Firmicutes,4HHN4@91061|Bacilli,1ZEF3@1386|Bacillus 91061|Bacilli S Uncharacterised 5xTM membrane BCR, YitT family COG1284 - - - - - - - - - - - - YitT_membrane k141_28859_1 59538.XP_005959973.1 5.02e-21 91.3 COG1087@1|root,KOG1371@2759|Eukaryota 2759|Eukaryota M racemase and epimerase activity, acting on carbohydrates and derivatives SQD1 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006643,GO:0006664,GO:0006950,GO:0007154,GO:0008146,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0009058,GO:0009247,GO:0009267,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009605,GO:0009987,GO:0009991,GO:0016036,GO:0016740,GO:0016782,GO:0019899,GO:0019904,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042594,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046467,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0101016,GO:1901135,GO:1901137,GO:1901576,GO:1903509 3.13.1.1,5.1.3.3 ko:K01785,ko:K06118 ko00010,ko00052,ko00520,ko00561,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map00520,map00561,map01100,map01110,map01120,map01130 M00632 R01602,R05775,R10619 RC00563,RC01469 ko00000,ko00001,ko00002,ko01000 - - - Aldose_epim,Epimerase k141_25267_1 1392488.JHZY01000002_gene1619 2.25e-07 52.4 2DSTI@1|root,33HD4@2|Bacteria,4NYHV@976|Bacteroidetes,1I6QF@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - k141_6355_1 218284.CCDN010000001_gene1159 4.29e-128 374.0 COG3359@1|root,COG3359@2|Bacteria,1TQQU@1239|Firmicutes,4HDMU@91061|Bacilli,1ZAZQ@1386|Bacillus 91061|Bacilli L RNase_H superfamily yprB - - ko:K07502 - - - - ko00000 - - - RNase_H_2 k141_7427_2 1279017.AQYJ01000027_gene1639 1.21e-266 741.0 COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,1RMB9@1236|Gammaproteobacteria,464ZX@72275|Alteromonadaceae 1236|Gammaproteobacteria O ATPase with chaperone activity comM GO:0003674,GO:0003824,GO:0004176,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0042623,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - ko:K07391 - - - - ko00000 - - - ChlI,Mg_chelatase,Mg_chelatase_C k141_7427_3 1448139.AI20_19015 2.88e-10 58.5 COG2960@1|root,COG2960@2|Bacteria,1N7AH@1224|Proteobacteria,1SCH1@1236|Gammaproteobacteria,1Y4SJ@135624|Aeromonadales 135624|Aeromonadales S Membrane fusogenic activity - - - ko:K09806 - - - - ko00000 - - - BMFP k141_7427_4 1279017.AQYJ01000027_gene1636 7.47e-115 335.0 2C5U9@1|root,2Z9NJ@2|Bacteria,1R6D0@1224|Proteobacteria,1SAQZ@1236|Gammaproteobacteria,46861@72275|Alteromonadaceae 1236|Gammaproteobacteria S Bacterial protein of unknown function (Gcw_chp) - - - - - - - - - - - - Gcw_chp k141_7427_6 1042377.AFPJ01000054_gene1697 7.6e-272 747.0 COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,1RNKF@1236|Gammaproteobacteria,4652P@72275|Alteromonadaceae 1236|Gammaproteobacteria P Ammonium transporter amtB - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - Ammonium_transp k141_2694_1 298654.FraEuI1c_0735 2.04e-44 158.0 COG0613@1|root,COG0613@2|Bacteria,2GNAP@201174|Actinobacteria,4ERF3@85013|Frankiales 201174|Actinobacteria S phosphoesterase, PHP PPA1328 - 3.1.3.97,3.1.4.57 ko:K07053,ko:K20859 ko00440,map00440 - R00188,R10972,R10973,R11188 RC00078,RC00296 ko00000,ko00001,ko01000 - - - PHP k141_2694_2 269799.Gmet_0504 2.32e-07 52.8 COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,1NPFY@1224|Proteobacteria,42PRW@68525|delta/epsilon subdivisions,2WIMG@28221|Deltaproteobacteria,43SUD@69541|Desulfuromonadales 28221|Deltaproteobacteria H Methylenetetrahydrofolate reductase metF-2 - 1.5.1.20,2.1.1.10 ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 M00377 R00650,R01224,R07168 RC00003,RC00035,RC00081 ko00000,ko00001,ko00002,ko01000 - - iAF987.Gmet_0504 MTHFR,S-methyl_trans k141_28877_1 1116375.VEJY3_08200 4.12e-133 383.0 COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,1RMZ5@1236|Gammaproteobacteria,1XSK3@135623|Vibrionales 135623|Vibrionales M Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)- (lauroyl)-lipid IV(A) lpxL - 2.3.1.241 ko:K02517 ko00540,ko01100,map00540,map01100 M00060 R05146 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Lip_A_acyltrans k141_35904_1 1279017.AQYJ01000022_gene2651 2.58e-101 294.0 COG1522@1|root,COG1522@2|Bacteria,1RM1D@1224|Proteobacteria,1S7W1@1236|Gammaproteobacteria,46AMQ@72275|Alteromonadaceae 1236|Gammaproteobacteria K helix_turn_helix ASNC type - - - - - - - - - - - - AsnC_trans_reg,HTH_24,HTH_AsnC-type k141_33554_1 218284.CCDN010000006_gene3513 1.42e-163 464.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,1ZBKX@1386|Bacillus 91061|Bacilli I Belongs to the thiolase family fadA - 2.3.1.16 ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 M00087,M00113 R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095 RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955 ko00000,ko00001,ko00002,ko01000 - - - Thiolase_C,Thiolase_N k141_21708_1 223926.28808065 5.43e-75 226.0 COG2922@1|root,COG2922@2|Bacteria,1RD5F@1224|Proteobacteria,1S43X@1236|Gammaproteobacteria,1XTHN@135623|Vibrionales 135623|Vibrionales S Belongs to the Smg family smg - - ko:K03747 - - - - ko00000 - - - DUF494 k141_21708_2 1219076.N646_2136 7.23e-91 270.0 COG0551@1|root,COG0551@2|Bacteria,1MX2E@1224|Proteobacteria,1RQ85@1236|Gammaproteobacteria,1XUJR@135623|Vibrionales 135623|Vibrionales L COG0551 Zn-finger domain associated with topoisomerase type I yrdD - - ko:K07479 - - - - ko00000 - - - zf-C4_Topoisom k141_21708_3 223926.28808063 1.06e-137 397.0 COG0026@1|root,COG0026@2|Bacteria,1MU70@1224|Proteobacteria,1RQEI@1236|Gammaproteobacteria,1XU8Y@135623|Vibrionales 135623|Vibrionales F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) purK GO:0003674,GO:0003824,GO:0004638,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.18 ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07404 RC01927 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp k141_25268_1 218284.CCDN010000001_gene286 6.71e-82 265.0 COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,4H9SP@91061|Bacilli,1ZAPS@1386|Bacillus 91061|Bacilli P COG2217 Cation transport ATPase - - 3.6.3.3,3.6.3.5 ko:K01534 - - - - ko00000,ko01000 3.A.3.6 - - E1-E2_ATPase,HMA,Hydrolase k141_3913_2 1294265.JCM21738_1872 9.44e-92 276.0 COG0604@1|root,COG0604@2|Bacteria,1TPGR@1239|Firmicutes,4HACF@91061|Bacilli,1ZCGD@1386|Bacillus 91061|Bacilli C Quinone oxidoreductase yhfP - 1.1.1.1 ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N k141_19296_1 35841.BT1A1_2435 1.05e-70 223.0 COG0491@1|root,COG0491@2|Bacteria,1TQGU@1239|Firmicutes,4HBJ3@91061|Bacilli,1ZB0U@1386|Bacillus 91061|Bacilli S COG0491 Zn-dependent hydrolases, including glyoxylases yflN - - - - - - - - - - - Lactamase_B k141_37076_1 37659.JNLN01000001_gene1575 2.66e-18 91.7 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,248ZJ@186801|Clostridia,36DK9@31979|Clostridiaceae 186801|Clostridia L snf2 family - - 2.7.11.1 ko:K08282 - - - - ko00000,ko01000 - - - Helicase_C,SNF2_N,SNF2_assoc,SWIM k141_31234_1 218284.CCDN010000001_gene1813 4.52e-101 306.0 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli,1ZAXK@1386|Bacillus 91061|Bacilli C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively iolA - 1.2.1.18,1.2.1.27 ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 M00013 R00705,R00706,R00922,R00935 RC00004,RC02723,RC02817 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_26608_1 349521.HCH_04158 1.04e-11 69.3 2EFH2@1|root,3399N@2|Bacteria,1NE4K@1224|Proteobacteria,1SFCY@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_13413_1 218284.CCDN010000001_gene1121 4.58e-66 213.0 COG0457@1|root,COG0457@2|Bacteria,1TT97@1239|Firmicutes,4HAIA@91061|Bacilli,1ZAZM@1386|Bacillus 91061|Bacilli S COG0457 FOG TPR repeat ypiA - - - - - - - - - - - TPR_16,TPR_19,TPR_2,TPR_7,TPR_8 k141_18191_2 439292.Bsel_0884 1.83e-05 52.8 COG3947@1|root,COG3947@2|Bacteria,1UZAW@1239|Firmicutes,4HA8P@91061|Bacilli,26PQB@186821|Sporolactobacillaceae 91061|Bacilli K PFAM response regulator receiver - - - - - - - - - - - - BTAD,Response_reg,Trans_reg_C k141_24039_2 1174504.AJTN02000046_gene2117 2.51e-50 164.0 COG1670@1|root,COG1670@2|Bacteria,1V97U@1239|Firmicutes,4HW07@91061|Bacilli,1ZET6@1386|Bacillus 91061|Bacilli J Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_3 k141_20432_1 1279017.AQYJ01000028_gene2332 5.32e-148 429.0 COG0397@1|root,COG0397@2|Bacteria,1MVK3@1224|Proteobacteria,1RNCS@1236|Gammaproteobacteria,4646G@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the UPF0061 (SELO) family ydiU - - ko:K08997 - - - - ko00000 - - - UPF0061 k141_28878_1 1453501.JELR01000002_gene868 8.42e-91 291.0 COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,1RYP9@1236|Gammaproteobacteria,465IE@72275|Alteromonadaceae 1236|Gammaproteobacteria E ERAP1-like C-terminal domain - - 3.4.11.14 ko:K01263 - - - - ko00000,ko01000 - - - ERAP1_C,Peptidase_M1 k141_21709_1 1121918.ARWE01000001_gene260 5.24e-09 55.8 COG2888@1|root,COG2888@2|Bacteria 2|Bacteria J peptidyl-tyrosine sulfation ybeL - 1.17.4.1,4.6.1.1 ko:K00525,ko:K01768 ko00230,ko00240,ko01100,ko02025,ko04113,ko04213,map00230,map00240,map01100,map02025,map04113,map04213 M00053,M00695 R00089,R00434,R02017,R02018,R02019,R02024 RC00295,RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - DUF1451 k141_21709_2 1121918.ARWE01000001_gene754 1.06e-14 70.5 COG2716@1|root,COG2716@2|Bacteria,1Q2TM@1224|Proteobacteria,42W89@68525|delta/epsilon subdivisions,2WSEF@28221|Deltaproteobacteria,43V1Y@69541|Desulfuromonadales 28221|Deltaproteobacteria E ACT domain - - - - - - - - - - - - ACT_6 k141_22914_1 1279017.AQYJ01000024_gene1130 2.16e-98 301.0 COG3303@1|root,COG3303@2|Bacteria,1R5JF@1224|Proteobacteria,1S13K@1236|Gammaproteobacteria,4667Z@72275|Alteromonadaceae 1236|Gammaproteobacteria P Cytochrome c3 - - - - - - - - - - - - Cytochrom_C552,Cytochrom_c3_2 k141_22914_2 1279017.AQYJ01000024_gene1129 1.49e-98 289.0 COG0840@1|root,COG0840@2|Bacteria,1RCTF@1224|Proteobacteria,1S317@1236|Gammaproteobacteria,466YK@72275|Alteromonadaceae 1236|Gammaproteobacteria NT Protein of unknown function (DUF3365) - - - - - - - - - - - - DUF3365 k141_2695_1 675815.VOA_001014 7.65e-21 87.4 COG5361@1|root,COG5361@2|Bacteria,1R799@1224|Proteobacteria,1RS9T@1236|Gammaproteobacteria,1XW9B@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF1214) - - - - - - - - - - - - DUF1214,DUF1254 k141_33555_1 1405.DJ92_4074 6.11e-117 350.0 COG0155@1|root,COG0155@2|Bacteria,1TS58@1239|Firmicutes,4HBEX@91061|Bacilli,1ZBHT@1386|Bacillus 91061|Bacilli P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate nirA - 1.7.7.1 ko:K00366 ko00910,ko01120,map00910,map01120 M00531 R00790 RC00176 ko00000,ko00001,ko00002,ko01000 - - - NIR_SIR,NIR_SIR_ferr k141_13414_2 218284.CCDN010000001_gene1789 6.83e-51 163.0 2EUDS@1|root,33MW4@2|Bacteria,1VHIA@1239|Firmicutes,4HSFG@91061|Bacilli,1ZEP8@1386|Bacillus 91061|Bacilli S Sporulation inhibitor of replication protein sirA yneE - - - - - - - - - - - SirA k141_29938_1 4098.XP_009628602.1 4.89e-12 70.5 COG1080@1|root,2QREJ@2759|Eukaryota,37RGD@33090|Viridiplantae,3G7H6@35493|Streptophyta,44BQJ@71274|asterids 35493|Streptophyta F Pyruvate, phosphate dikinase - GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464 2.7.9.1 ko:K01006 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 M00169,M00171,M00172,M00173 R00206 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - PEP-utilizers,PEP-utilizers_C,PPDK_N k141_3914_1 574375.BAGA_19100 1.13e-94 290.0 COG0305@1|root,COG0305@2|Bacteria,1VRFM@1239|Firmicutes,4HTBM@91061|Bacilli 91061|Bacilli L DnaB-like helicase C terminal domain - - - - - - - - - - - - DnaB_C k141_35905_1 1379270.AUXF01000001_gene2161 2.07e-40 149.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG1146@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,COG1146@2|Bacteria 2|Bacteria C 4 iron, 4 sulfur cluster binding nifJ - 1.2.7.1 ko:K03737 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00173,M00307 R01196,R10866 RC00004,RC02742 br01601,ko00000,ko00001,ko00002,ko01000 - - - EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C k141_28942_1 1307436.PBF_19198 1.85e-61 189.0 COG4837@1|root,COG4837@2|Bacteria,1VA2D@1239|Firmicutes,4HKZN@91061|Bacilli,1ZI07@1386|Bacillus 91061|Bacilli S protein conserved in bacteria yuzD - - - - - - - - - - - DUF1462 k141_24158_1 420246.GTNG_1303 5.22e-05 44.7 COG0572@1|root,COG0572@2|Bacteria,1V4T0@1239|Firmicutes,4HHU2@91061|Bacilli,1WGGR@129337|Geobacillus 91061|Bacilli F Phosphoribulokinase / Uridine kinase family - - 2.7.1.48 ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PRK k141_24158_3 796606.BMMGA3_09720 1.55e-56 179.0 COG0454@1|root,COG0454@2|Bacteria,1UIZH@1239|Firmicutes,4ISYE@91061|Bacilli,1ZS8E@1386|Bacillus 91061|Bacilli K Acetyltransferase (GNAT) family - - - - - - - - - - - - Acetyltransf_1 k141_14655_1 218284.CCDN010000006_gene3556 7.09e-102 302.0 COG2141@1|root,COG2141@2|Bacteria,1TPRS@1239|Firmicutes,4H9R2@91061|Bacilli,1ZB1E@1386|Bacillus 91061|Bacilli C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases yceB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - - - - - - - - - - Bac_luciferase k141_26785_1 502025.Hoch_4149 2.54e-31 124.0 COG1115@1|root,COG1115@2|Bacteria,1MUI3@1224|Proteobacteria,42MG1@68525|delta/epsilon subdivisions,2WKHE@28221|Deltaproteobacteria,2YYFS@29|Myxococcales 28221|Deltaproteobacteria E alanine symporter - - - ko:K03310 - - - - ko00000 2.A.25 - - Na_Ala_symp k141_1565_1 720555.BATR1942_12900 4.32e-110 328.0 COG0156@1|root,COG0156@2|Bacteria,1TPUX@1239|Firmicutes,4HAH3@91061|Bacilli,1ZAUZ@1386|Bacillus 91061|Bacilli H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide bioF GO:0003674,GO:0003824,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008710,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.3.1.29,2.3.1.47 ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 M00123,M00573,M00577 R00371,R03210,R10124 RC00004,RC00039,RC00394,RC02725 ko00000,ko00001,ko00002,ko01000,ko01007 - - iSB619.SA_RS12695 Aminotran_1_2 k141_1565_2 720555.BATR1942_12910 1.61e-44 151.0 COG1424@1|root,COG1424@2|Bacteria,1V38Y@1239|Firmicutes,4HJME@91061|Bacilli,1ZEA6@1386|Bacillus 91061|Bacilli H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP bioW - 6.2.1.14 ko:K01906 ko00780,ko01100,map00780,map01100 M00577 R03209 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - BioW k141_6452_1 218284.CCDN010000008_gene4248 1.22e-198 558.0 COG0162@1|root,COG0162@2|Bacteria,1TPGN@1239|Firmicutes,4H9YV@91061|Bacilli,1ZBY9@1386|Bacillus 91061|Bacilli J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) tyrS GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - S4,tRNA-synt_1b k141_4069_1 1385935.N836_05380 7.04e-43 153.0 COG0176@1|root,COG0176@2|Bacteria,1G15G@1117|Cyanobacteria,1HH9B@1150|Oscillatoriales 1117|Cyanobacteria H Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway tal - 2.2.1.2 ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01827 RC00439,RC00604 ko00000,ko00001,ko00002,ko01000 - - - TAL_FSA k141_15859_1 42565.FP66_07005 1.67e-36 123.0 COG1551@1|root,COG1551@2|Bacteria,1N6PG@1224|Proteobacteria,1SCB4@1236|Gammaproteobacteria,1XKZ6@135619|Oceanospirillales 135619|Oceanospirillales T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding csrA - - ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 - - - ko00000,ko00001,ko03019 - - - CsrA k141_25448_1 935836.JAEL01000073_gene3083 2.41e-159 457.0 COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,4HA98@91061|Bacilli,1ZDG5@1386|Bacillus 91061|Bacilli JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures cshB GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0070035,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 3.6.4.13 ko:K05592,ko:K18692 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,Helicase_C k141_37214_2 1294265.JCM21738_1829 2.64e-34 133.0 COG3468@1|root,COG3468@2|Bacteria 2|Bacteria MU cell adhesion - - - ko:K18491 ko04550,map04550 - - - ko00000,ko00001,ko03000 - - - Collagen,DUF4132,Gln_amidase k141_21835_1 1042377.AFPJ01000030_gene509 3.2e-30 119.0 2DMIH@1|root,32RT1@2|Bacteria,1RDKU@1224|Proteobacteria,1SFC5@1236|Gammaproteobacteria,46CVG@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_7514_1 1279017.AQYJ01000021_gene2923 2.31e-73 237.0 COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,1RPHJ@1236|Gammaproteobacteria,464JR@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1960 Acyl-CoA dehydrogenases bcd - 1.3.8.1 ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 - R01175,R01178,R02661,R03172,R04751 RC00052,RC00068,RC00076,RC00120,RC00148 ko00000,ko00001,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N k141_20590_2 1279017.AQYJ01000028_gene2129 2.38e-41 141.0 COG3247@1|root,COG3247@2|Bacteria,1RH69@1224|Proteobacteria,1SAIB@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Short repeat of unknown function (DUF308) - - - - - - - - - - - - DUF308 k141_2770_1 223926.28807251 1.45e-229 637.0 COG1344@1|root,COG1344@2|Bacteria,1MV1N@1224|Proteobacteria,1RN0Y@1236|Gammaproteobacteria,1XSDK@135623|Vibrionales 135623|Vibrionales N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella flaB GO:0005575,GO:0005576,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 - - - ko00000,ko00001,ko02035 - - - Flagellin_C,Flagellin_IN,Flagellin_N k141_2770_2 1116375.VEJY3_11625 7.49e-76 229.0 COG1334@1|root,COG1334@2|Bacteria,1NH9T@1224|Proteobacteria,1SH7I@1236|Gammaproteobacteria,1XX73@135623|Vibrionales 135623|Vibrionales N flagellar protein FlaG flaG - - ko:K06603 - - - - ko00000,ko02035 - - - FlaG k141_2770_3 223926.28807249 0.0 1013.0 COG1345@1|root,COG1345@2|Bacteria,1MUVP@1224|Proteobacteria,1RS2S@1236|Gammaproteobacteria,1XU55@135623|Vibrionales 135623|Vibrionales N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end fliD GO:0001539,GO:0003674,GO:0005198,GO:0005575,GO:0005576,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009420,GO:0009421,GO:0009424,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0097588 - ko:K02407 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flagellin_IN,FliD_C,FliD_N k141_2770_4 223926.28807248 6.11e-48 155.0 2AWMQ@1|root,31NIF@2|Bacteria,1QK94@1224|Proteobacteria,1TICJ@1236|Gammaproteobacteria,1XYVG@135623|Vibrionales 135623|Vibrionales - - flaI - - ko:K06604 - - - - ko00000 - - - - k141_2770_5 223926.28807247 1.52e-87 258.0 COG1516@1|root,COG1516@2|Bacteria,1MZ3G@1224|Proteobacteria,1S8TQ@1236|Gammaproteobacteria,1XWX6@135623|Vibrionales 135623|Vibrionales N Flagellar protein FliS fliS GO:0003674,GO:0005198 - ko:K02422 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FliS k141_2770_6 1116375.VEJY3_11600 0.0 899.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1T1IW@1236|Gammaproteobacteria,1XT5N@135623|Vibrionales 135623|Vibrionales T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains flaK - - ko:K10941 ko02020,ko02025,ko05111,map02020,map02025,map05111 - - - ko00000,ko00001,ko03000 - - - FleQ,HTH_8,Sigma54_activat k141_2770_7 1116375.VEJY3_11595 1.33e-229 634.0 COG5000@1|root,COG5000@2|Bacteria,1QUG9@1224|Proteobacteria,1T1Y1@1236|Gammaproteobacteria,1XSAF@135623|Vibrionales 135623|Vibrionales T COG0642 Signal transduction histidine kinase flrB - 2.7.13.3 ko:K10942 ko02020,ko05111,map02020,map05111 M00515 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS_8 k141_2770_8 1116375.VEJY3_11590 0.0 879.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1XU64@135623|Vibrionales 135623|Vibrionales T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains flrC - - ko:K10943 ko02020,ko05111,map02020,map05111 M00515 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat k141_2770_9 1116375.VEJY3_11585 3.13e-60 186.0 COG1677@1|root,COG1677@2|Bacteria,1N6RZ@1224|Proteobacteria,1SD52@1236|Gammaproteobacteria,1XXSM@135623|Vibrionales 135623|Vibrionales N Flagellar hook-basal body fliE - - ko:K02408 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FliE k141_2770_10 1219076.N646_1356 0.0 1037.0 COG1766@1|root,COG1766@2|Bacteria,1MUQR@1224|Proteobacteria,1RN6T@1236|Gammaproteobacteria,1XTYM@135623|Vibrionales 135623|Vibrionales N The M ring may be actively involved in energy transduction fliF - - ko:K02409 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 - - YscJ_FliF,YscJ_FliF_C k141_2770_11 1116375.VEJY3_11575 6.32e-232 640.0 COG1536@1|root,COG1536@2|Bacteria,1MV9X@1224|Proteobacteria,1RM9B@1236|Gammaproteobacteria,1XSQJ@135623|Vibrionales 135623|Vibrionales N FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation fliG GO:0005575,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - ko:K02410 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02035 - - - FliG_C,FliG_M,FliG_N k141_2770_12 1219076.N646_1354 1.67e-150 427.0 COG1317@1|root,COG1317@2|Bacteria,1RB8Y@1224|Proteobacteria,1T18Q@1236|Gammaproteobacteria,1XTTU@135623|Vibrionales 135623|Vibrionales N COG1317 Flagellar biosynthesis type III secretory pathway protein fliH - - ko:K02411 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - FliH,Yae1_N k141_2770_13 1280001.BAOA01000009_gene4177 2.78e-307 838.0 COG1157@1|root,COG1157@2|Bacteria,1MUH6@1224|Proteobacteria,1RM9W@1236|Gammaproteobacteria,1XTKF@135623|Vibrionales 135623|Vibrionales NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase fliI - 3.6.3.14 ko:K02412 ko02040,map02040 - - - ko00000,ko00001,ko01000,ko02035,ko02044 3.A.6.2,3.A.6.3 - - ATP-synt_ab k141_2770_14 1116375.VEJY3_11560 8.14e-86 254.0 COG2882@1|root,COG2882@2|Bacteria,1NANM@1224|Proteobacteria,1SD9U@1236|Gammaproteobacteria,1XXD9@135623|Vibrionales 135623|Vibrionales N COG2882 Flagellar biosynthesis chaperone fliJ - - ko:K02413 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FliJ k141_2770_15 1116375.VEJY3_11555 2.89e-120 373.0 COG3144@1|root,COG3144@2|Bacteria,1N7XT@1224|Proteobacteria,1SCA6@1236|Gammaproteobacteria,1XSXC@135623|Vibrionales 135623|Vibrionales N Flagellar hook-length control protein fliK - - ko:K02414 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_hook k141_2770_16 1280001.BAOA01000009_gene4173 7.24e-68 210.0 COG1580@1|root,COG1580@2|Bacteria,1RG10@1224|Proteobacteria,1S7UD@1236|Gammaproteobacteria,1XX17@135623|Vibrionales 135623|Vibrionales N Controls the rotational direction of flagella during chemotaxis fliL - - ko:K02415 - - - - ko00000,ko02035 - - - FliL k141_2770_17 223926.28807235 1.76e-236 652.0 COG1868@1|root,COG1868@2|Bacteria,1MX01@1224|Proteobacteria,1RQ8M@1236|Gammaproteobacteria,1XTRA@135623|Vibrionales 135623|Vibrionales N FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation fliM - - ko:K02416 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02035 - - - FliM,FliMN_C k141_2770_18 674977.VMC_12380 1.46e-85 253.0 COG1886@1|root,COG1886@2|Bacteria,1RGWT@1224|Proteobacteria,1S5YE@1236|Gammaproteobacteria,1XWWS@135623|Vibrionales 135623|Vibrionales N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation fliN - - ko:K02417 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 - - FliMN_C k141_2770_19 223926.28807233 5.92e-54 173.0 COG3190@1|root,COG3190@2|Bacteria,1PQ31@1224|Proteobacteria,1SGKN@1236|Gammaproteobacteria,1XY0C@135623|Vibrionales 135623|Vibrionales N COG3190 Flagellar biogenesis protein fliO - - ko:K02418 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - FliO k141_2770_20 223926.28807232 1.81e-177 498.0 COG1338@1|root,COG1338@2|Bacteria,1MVBU@1224|Proteobacteria,1RMYH@1236|Gammaproteobacteria,1XTA9@135623|Vibrionales 135623|Vibrionales N Plays a role in the flagellum-specific transport system fliP - - ko:K02419 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - FliP k141_2770_21 29495.EA26_17010 3.16e-49 157.0 COG1987@1|root,COG1987@2|Bacteria,1N73W@1224|Proteobacteria,1SCBG@1236|Gammaproteobacteria,1XXW8@135623|Vibrionales 135623|Vibrionales N Role in flagellar biosynthesis fliQ - - ko:K02420 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - Bac_export_3 k141_2770_22 223926.28807230 4.74e-170 476.0 COG1684@1|root,COG1684@2|Bacteria,1NIF4@1224|Proteobacteria,1RMYW@1236|Gammaproteobacteria,1XTE8@135623|Vibrionales 135623|Vibrionales N Role in flagellar biosynthesis fliR - - ko:K02421 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - Bac_export_1 k141_2770_23 1219076.N646_1340 1.96e-240 664.0 COG1377@1|root,COG1377@2|Bacteria,1MUWI@1224|Proteobacteria,1RMHA@1236|Gammaproteobacteria,1XTM7@135623|Vibrionales 135623|Vibrionales N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin flhB - - ko:K02401 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - Bac_export_2 k141_13636_1 42565.FP66_08760 2.41e-159 464.0 COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,1RMWP@1236|Gammaproteobacteria,1XI3G@135619|Oceanospirillales 135619|Oceanospirillales G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate tktA - 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C,Transketolase_N k141_18329_1 351348.Maqu_2170 8.68e-52 165.0 COG2329@1|root,COG2329@2|Bacteria,1RJMH@1224|Proteobacteria,1SAYM@1236|Gammaproteobacteria,4687E@72275|Alteromonadaceae 1236|Gammaproteobacteria S Antibiotic biosynthesis monooxygenase - - - - - - - - - - - - ABM k141_18329_2 1042377.AFPJ01000005_gene2468 3.49e-149 421.0 COG0704@1|root,COG0704@2|Bacteria,1MUMI@1224|Proteobacteria,1RMW5@1236|Gammaproteobacteria,466D2@72275|Alteromonadaceae 1236|Gammaproteobacteria P Plays a role in the regulation of phosphate uptake phoU GO:0000287,GO:0001558,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006873,GO:0006950,GO:0007154,GO:0008150,GO:0009266,GO:0009267,GO:0009268,GO:0009405,GO:0009408,GO:0009605,GO:0009628,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010563,GO:0010605,GO:0010629,GO:0010966,GO:0016020,GO:0016036,GO:0019220,GO:0019222,GO:0019725,GO:0019897,GO:0019898,GO:0022898,GO:0030002,GO:0030145,GO:0030320,GO:0030643,GO:0031323,GO:0031324,GO:0031667,GO:0031668,GO:0031669,GO:0032409,GO:0032410,GO:0032412,GO:0032413,GO:0032879,GO:0033554,GO:0034605,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0040008,GO:0042221,GO:0042592,GO:0042594,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043269,GO:0043271,GO:0044070,GO:0044092,GO:0044419,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045936,GO:0046677,GO:0046872,GO:0046914,GO:0046983,GO:0048519,GO:0048523,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0050896,GO:0051049,GO:0051051,GO:0051128,GO:0051174,GO:0051704,GO:0051716,GO:0055062,GO:0055081,GO:0055082,GO:0055083,GO:0060255,GO:0065007,GO:0065008,GO:0065009,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071496,GO:0071944,GO:0072501,GO:0072502,GO:0072505,GO:0072506,GO:0098771,GO:0104004,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - ko:K02039 - - - - ko00000 - - - PhoU k141_18329_3 1279017.AQYJ01000027_gene1862 2.51e-183 513.0 COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,1RNUF@1236|Gammaproteobacteria,464HW@72275|Alteromonadaceae 1236|Gammaproteobacteria P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system pstB - 3.6.3.27 ko:K02036 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 - - ABC_tran k141_18329_5 1042377.AFPJ01000005_gene2465 1.27e-218 616.0 COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,1RQXJ@1236|Gammaproteobacteria,464I5@72275|Alteromonadaceae 1236|Gammaproteobacteria P probably responsible for the translocation of the substrate across the membrane pstC - - ko:K02037 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1,DUF3708 k141_15860_1 493475.GARC_2407 9.86e-69 233.0 COG1629@1|root,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria,4652I@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec k141_12469_1 1116375.VEJY3_02905 9.45e-72 222.0 COG0235@1|root,COG0235@2|Bacteria,1MXV2@1224|Proteobacteria,1RP50@1236|Gammaproteobacteria,1XWCD@135623|Vibrionales 135623|Vibrionales G Rhamnulose-1-phosphate aldolase - - 4.1.2.19 ko:K01629 ko00040,ko00051,ko01120,map00040,map00051,map01120 - R01785,R02263 RC00438,RC00599,RC00603,RC00604 ko00000,ko00001,ko01000 - - - Aldolase_II k141_12469_2 1116375.VEJY3_02910 1.03e-226 629.0 COG4806@1|root,COG4806@2|Bacteria,1MW7Z@1224|Proteobacteria,1RPDX@1236|Gammaproteobacteria,1XW3I@135623|Vibrionales 135623|Vibrionales G Catalyzes the formation of L-rhamnulose from L-rhamnose - - 5.3.1.14 ko:K01813 ko00051,ko01120,map00051,map01120 - R02437 RC00434 ko00000,ko00001,ko01000 - - - RhaA k141_18354_1 218284.CCDN010000001_gene1763 4.61e-65 201.0 COG4767@1|root,COG4767@2|Bacteria,1VIHV@1239|Firmicutes,4HPUJ@91061|Bacilli 91061|Bacilli V VanZ like family - - - - - - - - - - - - VanZ k141_18354_2 218284.CCDN010000001_gene1764 1.07e-73 239.0 COG3276@1|root,COG3276@2|Bacteria,1TPQS@1239|Firmicutes,4HDD5@91061|Bacilli,1ZD2K@1386|Bacillus 91061|Bacilli J Selenocysteine-specific translation elongation factor selB - - ko:K03833 - - - - ko00000,ko03012 - - - GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3 k141_8824_1 1453501.JELR01000002_gene1115 2.48e-269 751.0 COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,1RNHP@1236|Gammaproteobacteria,46444@72275|Alteromonadaceae 1236|Gammaproteobacteria L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids dnaA GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006275,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010556,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1901576,GO:1990837,GO:2000112 - ko:K02313 ko02020,ko04112,map02020,map04112 - - - ko00000,ko00001,ko03032,ko03036 - - - Bac_DnaA,Bac_DnaA_C,DnaA_N k141_20606_1 935836.JAEL01000005_gene2701 9.79e-16 72.0 2E9EY@1|root,333N9@2|Bacteria,1VET0@1239|Firmicutes,4HP4N@91061|Bacilli,1ZIBK@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - Phage_connect_1 k141_20606_2 315730.BcerKBAB4_3587 1.53e-34 122.0 COG5614@1|root,COG5614@2|Bacteria,1VN3R@1239|Firmicutes,4IFGW@91061|Bacilli,1ZKKU@1386|Bacillus 91061|Bacilli S Phage head-tail joining protein - - - - - - - - - - - - Phage_H_T_join k141_20606_3 1235800.C819_02932 1.53e-23 95.1 2E357@1|root,32Y56@2|Bacteria,1VEJA@1239|Firmicutes,24J80@186801|Clostridia,27MA1@186928|unclassified Lachnospiraceae 186801|Clostridia S Bacteriophage HK97-gp10, putative tail-component - - - - - - - - - - - - HK97-gp10_like k141_4083_1 1279017.AQYJ01000028_gene2314 6.76e-202 580.0 COG0471@1|root,COG3273@1|root,COG0471@2|Bacteria,COG3273@2|Bacteria,1MU0K@1224|Proteobacteria,1RMI1@1236|Gammaproteobacteria,465YV@72275|Alteromonadaceae 1236|Gammaproteobacteria P Sodium:sulfate symporter transmembrane region - - - - - - - - - - - - CitMHS,Na_sulph_symp,TrkA_C k141_4083_2 1288826.MSNKSG1_12957 1.88e-117 353.0 COG2603@1|root,COG2603@2|Bacteria,1N4T5@1224|Proteobacteria,1RPFP@1236|Gammaproteobacteria,46469@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA selU GO:0001887,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016785,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043828,GO:0044237,GO:0044238,GO:0046483,GO:0070329,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 - ko:K06917 - - - - ko00000,ko01000,ko03016 - - - Rhodanese k141_4083_3 1453501.JELR01000005_gene1648 4.48e-178 501.0 COG4221@1|root,COG4221@2|Bacteria,1R83E@1224|Proteobacteria,1T1UP@1236|Gammaproteobacteria,46DB1@72275|Alteromonadaceae 1236|Gammaproteobacteria S KR domain - - - - - - - - - - - - adh_short k141_4083_4 1453501.JELR01000005_gene1647 1.29e-63 197.0 COG0346@1|root,COG0346@2|Bacteria,1N1HF@1224|Proteobacteria,1SFPY@1236|Gammaproteobacteria 1236|Gammaproteobacteria E lactoylglutathione lyase activity - - - - - - - - - - - - - k141_4083_6 1279017.AQYJ01000028_gene2302 2.43e-123 356.0 COG1451@1|root,COG1451@2|Bacteria,1MXZU@1224|Proteobacteria,1S9E4@1236|Gammaproteobacteria,467T2@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function DUF45 - - - ko:K07043 - - - - ko00000 - - - DUF45 k141_4083_7 305900.GV64_23350 5.38e-51 166.0 COG2050@1|root,COG2050@2|Bacteria,1RGVP@1224|Proteobacteria,1S5WY@1236|Gammaproteobacteria,1XMMW@135619|Oceanospirillales 135619|Oceanospirillales Q Thioesterase superfamily - - - - - - - - - - - - 4HBT k141_31314_1 177439.DP0187 1.83e-116 353.0 2DBH6@1|root,2Z97W@2|Bacteria,1RDRM@1224|Proteobacteria,42UZW@68525|delta/epsilon subdivisions,2WQTS@28221|Deltaproteobacteria 28221|Deltaproteobacteria S CRISPR-associated protein, GSU0054 family (Cas_GSU0054) - - - ko:K19132 - - - - ko00000,ko02048 - - - Cas_GSU0054 k141_10007_1 1283284.AZUK01000001_gene59 1.64e-64 201.0 COG3118@1|root,COG3118@2|Bacteria,1RHUA@1224|Proteobacteria,1S64W@1236|Gammaproteobacteria,1Y5VM@135624|Aeromonadales 135624|Aeromonadales O Thioredoxin-like domain - - 1.8.1.8 ko:K03672 - - - - ko00000,ko01000,ko03110 - - - Thioredoxin k141_24176_1 218284.CCDN010000005_gene3283 6.72e-155 441.0 COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,4HA4E@91061|Bacilli,1ZB72@1386|Bacillus 91061|Bacilli P Belongs to the ABC transporter superfamily oppD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY k141_24176_2 218284.CCDN010000005_gene3284 5.03e-09 55.8 COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,4H9YB@91061|Bacilli,1ZBA4@1386|Bacillus 91061|Bacilli E Belongs to the ABC transporter superfamily oppF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY k141_18355_1 1453501.JELR01000001_gene1875 2.93e-30 124.0 COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,1RMPT@1236|Gammaproteobacteria,464DD@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG3209 Rhs family protein - - - - - - - - - - - - RHS_repeat,SpvB,TcdB_toxin_midN,VCBS k141_12497_1 218284.CCDN010000005_gene3477 1.12e-148 428.0 COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,4H9VI@91061|Bacilli,1ZB6B@1386|Bacillus 91061|Bacilli G Belongs to the GPI family pgi GO:0003674,GO:0003824,GO:0004347,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGI k141_23134_1 234267.Acid_7936 4.82e-08 55.8 COG1566@1|root,COG1566@2|Bacteria,3Y9B7@57723|Acidobacteria 57723|Acidobacteria V Biotin-lipoyl like - - - ko:K02005 - - - - ko00000 - - - Biotin_lipoyl_2,HlyD_D23 k141_23134_2 497964.CfE428DRAFT_6511 8.16e-51 167.0 COG1136@1|root,COG1136@2|Bacteria,46SI5@74201|Verrucomicrobia 74201|Verrucomicrobia V PFAM ABC transporter related - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_36011_1 1294265.JCM21738_4029 9.26e-118 353.0 COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,4H9VQ@91061|Bacilli,1ZASE@1386|Bacillus 91061|Bacilli M Penicillin-binding Protein pbpX GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - - PASTA,PBP_dimer,Transpeptidase k141_11186_1 218284.CCDN010000006_gene3631 3.67e-85 252.0 COG1051@1|root,COG1051@2|Bacteria,1V3BX@1239|Firmicutes,4HGE6@91061|Bacilli,1ZFT4@1386|Bacillus 91061|Bacilli F Nudix hydrolase yvcI - 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - - NUDIX k141_21842_1 999550.KI421507_gene90 1.08e-62 192.0 COG0051@1|root,COG0051@2|Bacteria,1RGWF@1224|Proteobacteria,2U95D@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Involved in the binding of tRNA to the ribosomes rpsJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02946 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S10 k141_21842_2 1123237.Salmuc_01520 5.99e-42 145.0 COG0087@1|root,COG0087@2|Bacteria,1MUST@1224|Proteobacteria,2TRHB@28211|Alphaproteobacteria 28211|Alphaproteobacteria J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit rplC - - ko:K02906 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L3 k141_30063_1 42565.FP66_06475 1.69e-45 149.0 COG0049@1|root,COG0049@2|Bacteria,1MXC8@1224|Proteobacteria,1RN77@1236|Gammaproteobacteria,1XJC8@135619|Oceanospirillales 135619|Oceanospirillales J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA rpsG - - ko:K02992 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S7 k141_13659_1 1294265.JCM21738_3662 4.78e-48 161.0 COG0760@1|root,COG0760@2|Bacteria,1UZZM@1239|Firmicutes,4HE14@91061|Bacilli,1ZBFZ@1386|Bacillus 91061|Bacilli O peptidyl-prolyl isomerase yacD - 5.2.1.8 ko:K07533 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_2,Rotamase_3,SurA_N_3 k141_13659_2 1294265.JCM21738_3661 1.1e-200 556.0 COG1281@1|root,COG1281@2|Bacteria,1TRCH@1239|Firmicutes,4HAFR@91061|Bacilli,1ZBFC@1386|Bacillus 91061|Bacilli O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress hslO - - ko:K04083 - - - - ko00000,ko03110 - - - HSP33 k141_28962_1 345219.Bcoa_0553 3.81e-226 634.0 COG0477@1|root,COG2814@2|Bacteria,1TPRN@1239|Firmicutes,4H9VV@91061|Bacilli,1ZAXQ@1386|Bacillus 91061|Bacilli EGP the major facilitator superfamily - - - - - - - - - - - - MFS_1 k141_23135_1 666686.B1NLA3E_19890 1.4e-99 323.0 COG1674@1|root,COG1716@1|root,COG1674@2|Bacteria,COG1716@2|Bacteria,1TRA4@1239|Firmicutes,4H9QM@91061|Bacilli,1ZDSN@1386|Bacillus 91061|Bacilli D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins essC - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FHA,FtsK_SpoIIIE,FtsK_SpoIIIE_N k141_18356_1 198467.NP92_05395 2.48e-45 162.0 COG1807@1|root,COG1807@2|Bacteria,1TR0R@1239|Firmicutes,4HBI2@91061|Bacilli,21WI7@150247|Anoxybacillus 91061|Bacilli M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - - - - - - - - - - PMT_2 k141_11187_1 218284.CCDN010000001_gene1144 2.44e-67 208.0 COG5353@1|root,COG5353@2|Bacteria,1VA2H@1239|Firmicutes,4HNMM@91061|Bacilli,1ZFVJ@1386|Bacillus 91061|Bacilli S protein conserved in bacteria ypmB - - - - - - - - - - - PepSY k141_582_2 1294265.JCM21738_2077 2.42e-17 77.4 COG4940@1|root,COG4940@2|Bacteria,1VKRP@1239|Firmicutes,4HR6S@91061|Bacilli,1ZIZV@1386|Bacillus 91061|Bacilli U COG4940 Competence protein ComGF comGF - - ko:K02248 - M00429 - - ko00000,ko00002,ko02044 - - - ComGF,N_methyl k141_5236_1 1000565.METUNv1_01440 7.46e-37 135.0 COG0560@1|root,COG0560@2|Bacteria 2|Bacteria E Phosphoserine phosphatase - - 3.1.3.3 ko:K01079 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R00582 RC00017 ko00000,ko00001,ko00002,ko01000,ko01009 - - - HAD,Hydrolase k141_32524_1 279010.BL01885 9.2e-08 52.4 COG1386@1|root,COG1386@2|Bacteria,1V6HI@1239|Firmicutes,4HIQ0@91061|Bacilli,1ZFNU@1386|Bacillus 91061|Bacilli D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves scpB GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K06024 - - - - ko00000,ko03036 - - - SMC_ScpB k141_32524_2 1294265.JCM21738_41 1.51e-93 273.0 2A9NA@1|root,30YV1@2|Bacteria,1V47Y@1239|Firmicutes,4HIDD@91061|Bacilli,1ZGBG@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_7617_1 1116375.VEJY3_21256 3.94e-110 324.0 COG1566@1|root,COG1566@2|Bacteria,1MU7I@1224|Proteobacteria,1RPV2@1236|Gammaproteobacteria,1XUFT@135623|Vibrionales 135623|Vibrionales V Secretion protein - - - - - - - - - - - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 k141_7617_2 1116375.VEJY3_21251 6.59e-201 561.0 28NGY@1|root,33T95@2|Bacteria,1NSSN@1224|Proteobacteria,1SM6N@1236|Gammaproteobacteria,1XUSB@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF2955) - - - - - - - - - - - - DUF2955 k141_7617_3 223926.28806353 0.0 926.0 COG0624@1|root,COG0624@2|Bacteria,1MWJS@1224|Proteobacteria,1RZXV@1236|Gammaproteobacteria,1XVZK@135623|Vibrionales 135623|Vibrionales E Peptidase dimerisation domain - - - ko:K13049 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20,Peptidase_M28 k141_7617_4 1136163.M565_ctg5P1419 1.07e-83 253.0 COG3495@1|root,COG3495@2|Bacteria,1QK79@1224|Proteobacteria,1TIAH@1236|Gammaproteobacteria,1XYRH@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF3299) - - - - - - - - - - - - DUF3299 k141_7617_5 1116375.VEJY3_21246 1.99e-46 157.0 COG2240@1|root,COG2240@2|Bacteria,1MVC9@1224|Proteobacteria,1RMIE@1236|Gammaproteobacteria,1XSHI@135623|Vibrionales 135623|Vibrionales H Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP - - 2.7.1.35 ko:K00868 ko00750,ko01100,map00750,map01100 - R00174,R01909,R02493 RC00002,RC00017 ko00000,ko00001,ko01000 - - - Phos_pyr_kin k141_18490_1 1157490.EL26_07985 4.5e-14 82.0 COG4585@1|root,COG4585@2|Bacteria,1V49U@1239|Firmicutes,4HIC0@91061|Bacilli,279X0@186823|Alicyclobacillaceae 91061|Bacilli T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA_3 k141_18490_2 742823.HMPREF9465_00582 2.42e-26 106.0 COG2197@1|root,COG2197@2|Bacteria,1NQH7@1224|Proteobacteria,2VMXI@28216|Betaproteobacteria,4PQMY@995019|Sutterellaceae 28216|Betaproteobacteria K Bacterial regulatory proteins, luxR family narL - - ko:K07684 ko02020,map02020 M00471 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg k141_33859_1 329726.AM1_0693 2.21e-31 126.0 COG1994@1|root,COG1994@2|Bacteria,1G03A@1117|Cyanobacteria 1117|Cyanobacteria S PFAM Peptidase family M50 - - - - - - - - - - - - Peptidase_M50 k141_19614_1 42565.FP66_02425 1.79e-155 449.0 COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,1RPV9@1236|Gammaproteobacteria,1XHRW@135619|Oceanospirillales 135619|Oceanospirillales P Phosphate transport system permease protein pstA - - ko:K02038 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 k141_21938_3 764561.D7RWC5_9CAUD 2.86e-19 86.3 4QH25@10239|Viruses,4R0NR@35237|dsDNA viruses no RNA stage,4QQX7@28883|Caudovirales,4QMZG@10699|Siphoviridae 10699|Siphoviridae S Phage terminase large subunit - GO:0003674,GO:0003824,GO:0004518,GO:0005575,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016032,GO:0016787,GO:0016788,GO:0019058,GO:0019068,GO:0019072,GO:0019073,GO:0032991,GO:0034641,GO:0043170,GO:0043493,GO:0044237,GO:0044238,GO:0044403,GO:0044419,GO:0046483,GO:0051704,GO:0071704,GO:0090304,GO:0090305,GO:0098009,GO:1901360,GO:1902494,GO:1904949 - - - - - - - - - - - k141_15981_1 218284.CCDN010000001_gene1128 4.75e-17 79.0 28RMR@1|root,2ZE0H@2|Bacteria,1V1HS@1239|Firmicutes,4HFRG@91061|Bacilli,1ZANV@1386|Bacillus 91061|Bacilli S sporulation protein ypjB - - - - - - - - - - - Spore_YpjB k141_8948_1 1116375.VEJY3_05095 7.14e-67 203.0 2DGP6@1|root,2ZWSK@2|Bacteria,1P8MV@1224|Proteobacteria,1SVDC@1236|Gammaproteobacteria,1Y1P3@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_8948_2 1116375.VEJY3_05090 5.55e-142 402.0 2AWC7@1|root,31N80@2|Bacteria,1QJZE@1224|Proteobacteria,1TI1U@1236|Gammaproteobacteria,1XY6E@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_8948_4 1116375.VEJY3_05080 0.000504 38.9 2EITN@1|root,33CIY@2|Bacteria,1NJ3G@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_1653_1 218284.CCDN010000002_gene2395 4.54e-82 255.0 2DBJR@1|root,2Z9N7@2|Bacteria,1TRSN@1239|Firmicutes,4HCDI@91061|Bacilli,1ZN92@1386|Bacillus 91061|Bacilli S Spore germination B3/ GerAC like, C-terminal - - - - - - - - - - - - Spore_GerAC k141_2876_1 218284.CCDN010000001_gene1174 7.08e-86 261.0 COG2897@1|root,COG2897@2|Bacteria,1TRYA@1239|Firmicutes,4HAQA@91061|Bacilli,1ZANF@1386|Bacillus 91061|Bacilli P sulfurtransferase sseA - 2.8.1.1,2.8.1.2 ko:K01011 ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122 - R01931,R03105,R03106 RC00214 ko00000,ko00001,ko01000 - - - Rhodanese k141_7618_2 1294265.JCM21738_4474 2.29e-07 50.1 COG0782@1|root,COG0782@2|Bacteria,1V44S@1239|Firmicutes,4HGZU@91061|Bacilli,1ZFQI@1386|Bacillus 91061|Bacilli K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides greA GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - ko:K03624 - - - - ko00000,ko03021 - - - GreA_GreB,GreA_GreB_N k141_24276_2 997296.PB1_14444 9.68e-13 62.0 2BYGW@1|root,33J7Z@2|Bacteria,1W1WC@1239|Firmicutes,4HSU3@91061|Bacilli,1ZK1V@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_24276_3 218284.CCDN010000001_gene1024 1.29e-27 107.0 COG1073@1|root,COG1073@2|Bacteria,1TQYU@1239|Firmicutes,4HC4H@91061|Bacilli,1ZBDV@1386|Bacillus 91061|Bacilli S COG1073 Hydrolases of the alpha beta superfamily yqkD - - ko:K06889 - - - - ko00000 - - - Hydrolase_4 k141_19615_1 42565.FP66_04350 2e-117 348.0 COG0591@1|root,COG0591@2|Bacteria,1MUBI@1224|Proteobacteria,1RMXU@1236|Gammaproteobacteria,1XI4B@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family putP - - ko:K03307,ko:K11928 - - - - ko00000,ko02000 2.A.21,2.A.21.2 - - SSF k141_18492_1 1485545.JQLW01000006_gene297 2.89e-20 92.0 COG0515@1|root,COG4252@1|root,COG0515@2|Bacteria,COG4252@2|Bacteria,1MV1P@1224|Proteobacteria 1224|Proteobacteria KLT serine threonine protein kinase - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - CHASE2,Pkinase k141_18492_2 743299.Acife_1834 1.37e-11 63.2 COG1267@1|root,COG1267@2|Bacteria,1MZJA@1224|Proteobacteria,1S68A@1236|Gammaproteobacteria,2ND1S@225057|Acidithiobacillales 225057|Acidithiobacillales I Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) - - 3.1.3.27 ko:K01095 ko00564,ko01100,map00564,map01100 - R02029 RC00017 ko00000,ko00001,ko01000 - - - PgpA k141_695_1 391625.PPSIR1_16195 5.31e-13 70.5 COG0760@1|root,COG0760@2|Bacteria,1Q4IW@1224|Proteobacteria,43A0D@68525|delta/epsilon subdivisions,2X2FD@28221|Deltaproteobacteria,2Z2B6@29|Myxococcales 28221|Deltaproteobacteria M PPIC-type PPIASE domain - - - - - - - - - - - - Rotamase_3 k141_17157_2 1117379.BABA_20856 1.8e-86 263.0 COG1028@1|root,COG1028@2|Bacteria,1TZY6@1239|Firmicutes,4HEU2@91061|Bacilli,1ZCIS@1386|Bacillus 91061|Bacilli IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) ymfI - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short,adh_short_C2 k141_17157_3 218284.CCDN010000001_gene1863 2.74e-45 157.0 COG0612@1|root,COG0612@2|Bacteria,1TP5I@1239|Firmicutes,4H9YG@91061|Bacilli,1ZBXQ@1386|Bacillus 91061|Bacilli S zinc protease ymfH - - - - - - - - - - - Peptidase_M16,Peptidase_M16_C k141_8949_1 218284.CCDN010000008_gene4178 8.56e-55 172.0 29JW2@1|root,306TD@2|Bacteria,1U0BH@1239|Firmicutes,4I9NA@91061|Bacilli,1ZISQ@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2524) ytzC - - - - - - - - - - - DUF2524 k141_11352_1 1121091.AUMP01000044_gene3900 2.96e-65 201.0 COG2963@1|root,COG2963@2|Bacteria,1V771@1239|Firmicutes,4HJ16@91061|Bacilli 91061|Bacilli L Transposase and inactivated derivatives - - - - - - - - - - - - - k141_11352_2 666686.B1NLA3E_16890 4.29e-105 311.0 COG2801@1|root,COG2801@2|Bacteria,1TRR6@1239|Firmicutes,4HAJS@91061|Bacilli,1ZC3V@1386|Bacillus 91061|Bacilli L COG2801 Transposase and inactivated derivatives - - - ko:K07497 - - - - ko00000 - - - HTH_21,rve,rve_2 k141_33862_1 439235.Dalk_2494 9.39e-45 151.0 2EB22@1|root,3352W@2|Bacteria,1NE0W@1224|Proteobacteria,42VEE@68525|delta/epsilon subdivisions,2WRJF@28221|Deltaproteobacteria 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k141_27734_1 1523503.JPMY01000013_gene3466 1.41e-64 221.0 COG1345@1|root,COG1345@2|Bacteria,1MUVP@1224|Proteobacteria,1S11E@1236|Gammaproteobacteria 1236|Gammaproteobacteria N Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end fliD GO:0005575,GO:0005576,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - ko:K02407 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flagellin_IN,FliD_C,FliD_N k141_27734_2 223926.28809950 8.19e-108 321.0 COG1344@1|root,COG1344@2|Bacteria,1MV1N@1224|Proteobacteria,1RYIJ@1236|Gammaproteobacteria,1XUYM@135623|Vibrionales 135623|Vibrionales N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella hag GO:0005575,GO:0005576,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 - - - ko00000,ko00001,ko02035 - - - Flagellin_C,Flagellin_N k141_37333_1 218284.CCDN010000005_gene3238 2.38e-06 46.6 2CKSS@1|root,32W2Q@2|Bacteria,1VB9W@1239|Firmicutes,4HMC5@91061|Bacilli,1ZHSY@1386|Bacillus 91061|Bacilli S UPF0344 protein yisL - - - - - - - - - - - DUF1516 k141_37333_2 218284.CCDN010000005_gene3237 9.58e-173 486.0 COG0179@1|root,COG0179@2|Bacteria,1TQDQ@1239|Firmicutes,4HCBR@91061|Bacilli,1ZCHF@1386|Bacillus 91061|Bacilli Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) yisK - - - - - - - - - - - FAA_hydrolase k141_18493_1 218284.CCDN010000001_gene648 3.91e-83 249.0 2DGQY@1|root,32U7R@2|Bacteria,1V83A@1239|Firmicutes,4HKRI@91061|Bacilli,1ZH9Y@1386|Bacillus 91061|Bacilli S BofC C-terminal domain bofC - - ko:K06318 - - - - ko00000 - - - BOFC_N,BofC_C k141_15982_2 1453501.JELR01000002_gene1483 4.15e-109 332.0 COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,1RMWP@1236|Gammaproteobacteria,4651B@72275|Alteromonadaceae 1236|Gammaproteobacteria G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate tkt - 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C,Transketolase_N k141_30140_1 1279017.AQYJ01000024_gene992 5.05e-202 563.0 COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,1RMBM@1236|Gammaproteobacteria,464U3@72275|Alteromonadaceae 1236|Gammaproteobacteria G Catalyzes the NAD-dependent conversion of D-erythrose 4- phosphate to 4-phosphoerythronate gapA - 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N k141_30140_2 1453501.JELR01000002_gene193 1.64e-110 322.0 COG0800@1|root,COG0800@2|Bacteria,1MUVJ@1224|Proteobacteria,1RPDF@1236|Gammaproteobacteria,465M9@72275|Alteromonadaceae 1236|Gammaproteobacteria G COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase eda GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008675,GO:0008700,GO:0008948,GO:0016829,GO:0016830,GO:0016831,GO:0016832,GO:0016833,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0106009 4.1.2.14,4.1.3.42 ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 M00008,M00061,M00308,M00631 R00470,R05605 RC00307,RC00308,RC00435 ko00000,ko00001,ko00002,ko01000 - - iECOK1_1307.ECOK1_1968,iYL1228.KPN_02365 Aldolase k141_30140_3 1279017.AQYJ01000024_gene990 2.39e-134 384.0 COG0363@1|root,COG0363@2|Bacteria,1R5K6@1224|Proteobacteria,1S11C@1236|Gammaproteobacteria,464XJ@72275|Alteromonadaceae 1236|Gammaproteobacteria G COG0363 6-phosphogluconolactonase Glucosamine-6-phosphate isomerase deaminase pgl - 3.1.1.31 ko:K01057 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R02035 RC00537 ko00000,ko00001,ko00002,ko01000 - - - Glucosamine_iso k141_30140_4 1042377.AFPJ01000030_gene500 2.61e-292 805.0 COG0364@1|root,COG0364@2|Bacteria,1MUN0@1224|Proteobacteria,1RN76@1236|Gammaproteobacteria,464A8@72275|Alteromonadaceae 1236|Gammaproteobacteria G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone zwf - 1.1.1.363,1.1.1.49 ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 M00004,M00006,M00008 R00835,R02736,R10907 RC00001,RC00066 ko00000,ko00001,ko00002,ko01000,ko04147 - - - G6PD_C,G6PD_N k141_30140_5 1279017.AQYJ01000024_gene988 3.74e-23 98.6 COG0129@1|root,COG0129@2|Bacteria,1MU3T@1224|Proteobacteria,1RMNA@1236|Gammaproteobacteria,464QM@72275|Alteromonadaceae 1236|Gammaproteobacteria EG Belongs to the IlvD Edd family edd GO:0003674,GO:0003824,GO:0004456,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019520,GO:0019521,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0046176,GO:0046177,GO:0046395,GO:0071704,GO:0072329,GO:1901575 4.2.1.12 ko:K01690 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 M00008 R02036 RC00543 ko00000,ko00001,ko00002,ko01000 - - iEcolC_1368.EcolC_1781,iJN746.PP_1010,iPC815.YPO2533,iYL1228.KPN_02366 ILVD_EDD k141_10188_1 1042377.AFPJ01000051_gene108 1.07e-40 139.0 2CFS8@1|root,2ZFB8@2|Bacteria,1P495@1224|Proteobacteria,1STV4@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_10188_2 1279017.AQYJ01000028_gene2427 2.39e-88 265.0 COG2824@1|root,COG2824@2|Bacteria,1RGUU@1224|Proteobacteria,1S60W@1236|Gammaproteobacteria,466RW@72275|Alteromonadaceae 1236|Gammaproteobacteria P PhnA domain phnA - - ko:K06193 ko01120,map01120 - - - ko00000 - - - PhnA,PhnA_Zn_Ribbon k141_10188_3 1279017.AQYJ01000028_gene2426 6.66e-41 138.0 COG0517@1|root,COG0517@2|Bacteria,1QTVM@1224|Proteobacteria,1SFWU@1236|Gammaproteobacteria,46BCN@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain in cystathionine beta-synthase and other proteins. - - - - - - - - - - - - CBS k141_21940_1 218284.CCDN010000006_gene3530 1.12e-158 455.0 2DH6Y@1|root,2ZYKQ@2|Bacteria,1V3RR@1239|Firmicutes,4HHKE@91061|Bacilli,1ZBHI@1386|Bacillus 91061|Bacilli S Spore germination B3/ GerAC like, C-terminal - - - ko:K06308 - - - - ko00000 - - - Spore_GerAC k141_25643_1 218284.CCDN010000011_gene4420 1.59e-99 294.0 COG0171@1|root,COG0171@2|Bacteria,1TQ38@1239|Firmicutes,4HA2R@91061|Bacilli,1ZBM2@1386|Bacillus 91061|Bacilli H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source nadE GO:0000003,GO:0003674,GO:0003824,GO:0003952,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0016884,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019954,GO:0030436,GO:0032502,GO:0034641,GO:0034654,GO:0043934,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5 ko:K01916 ko00760,ko01100,map00760,map01100 M00115 R00189 RC00100 ko00000,ko00001,ko00002,ko01000 - - - NAD_synthase k141_25643_2 218284.CCDN010000011_gene4421 4.84e-208 577.0 COG0714@1|root,COG0714@2|Bacteria,1TPKR@1239|Firmicutes,4HA0T@91061|Bacilli,1ZDJ1@1386|Bacillus 91061|Bacilli S COG0714 MoxR-like ATPases yeaC GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 k141_24279_1 1027292.HMPREF9372_0728 1.16e-14 76.6 COG1589@1|root,COG1589@2|Bacteria,1V6V5@1239|Firmicutes,4HDFD@91061|Bacilli,26EUK@186818|Planococcaceae 91061|Bacilli D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex divIB - - ko:K03589 ko04112,map04112 - - - ko00000,ko00001,ko03036 - - - FtsQ,POTRA_1 k141_27735_1 1121091.AUMP01000052_gene1290 2.27e-52 176.0 COG2367@1|root,COG2367@2|Bacteria,1UYZ3@1239|Firmicutes,4HD7T@91061|Bacilli 91061|Bacilli V Beta-lactamase enzyme family - - 3.5.2.6 ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 M00627,M00628 R06363 RC01499 ko00000,ko00001,ko00002,ko01000,ko01504 - - - Beta-lactamase2 k141_12620_2 443152.MDG893_20399 3.12e-66 209.0 COG1182@1|root,COG1182@2|Bacteria,1P59R@1224|Proteobacteria,1S337@1236|Gammaproteobacteria,466Y8@72275|Alteromonadaceae 1236|Gammaproteobacteria I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity azoR - - ko:K01118 - - - - ko00000,ko01000 - - - Flavodoxin_2 k141_12620_3 1005395.CSV86_15770 1.24e-46 156.0 COG0590@1|root,COG0590@2|Bacteria,1RHM4@1224|Proteobacteria,1S6HT@1236|Gammaproteobacteria 1236|Gammaproteobacteria FJ MafB19-like deaminase - - - - - - - - - - - - MafB19-deam,dCMP_cyt_deam_1 k141_12620_4 1128912.GMES_2858 8.5e-92 293.0 COG4773@1|root,COG4773@2|Bacteria,1NXPR@1224|Proteobacteria,1RSBC@1236|Gammaproteobacteria,4657C@72275|Alteromonadaceae 1236|Gammaproteobacteria P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec k141_14747_1 1116375.VEJY3_14540 1.25e-181 516.0 COG5002@1|root,COG5002@2|Bacteria,1QUGI@1224|Proteobacteria,1T1Y9@1236|Gammaproteobacteria,1XT99@135623|Vibrionales 135623|Vibrionales T sensor protein cpxA - 2.7.13.3 ko:K07640 ko01503,ko02020,map01503,map02020 M00447,M00727,M00728 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - CpxA_peri,HAMP,HATPase_c,HisKA k141_14747_2 1219076.N646_1949 3.4e-111 319.0 COG0219@1|root,COG0219@2|Bacteria,1RCY4@1224|Proteobacteria,1S3PI@1236|Gammaproteobacteria,1XUPR@135623|Vibrionales 135623|Vibrionales J Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide trmL - 2.1.1.207 ko:K03216 - - - - ko00000,ko01000,ko03016 - - - SpoU_methylase k141_14747_3 1116375.VEJY3_14550 2.79e-94 278.0 COG3030@1|root,COG3030@2|Bacteria,1MZJJ@1224|Proteobacteria,1S8XU@1236|Gammaproteobacteria,1XVK9@135623|Vibrionales 135623|Vibrionales S COG3030 Protein affecting phage T7 exclusion by the F plasmid fxsA - - ko:K07113 - - - - ko00000 - - - FxsA k141_35063_1 1116375.VEJY3_19526 2.16e-210 594.0 COG2199@1|root,COG3706@2|Bacteria,1MWHH@1224|Proteobacteria,1RRU7@1236|Gammaproteobacteria,1XW43@135623|Vibrionales 135623|Vibrionales T diguanylate cyclase - - - - - - - - - - - - 7TMR-DISMED2,7TMR-DISM_7TM,CHASE4,GGDEF k141_35063_2 1116375.VEJY3_19521 2.43e-129 377.0 COG5607@1|root,COG5607@2|Bacteria,1R5I1@1224|Proteobacteria,1S0QK@1236|Gammaproteobacteria,1XXG6@135623|Vibrionales 135623|Vibrionales S CHAD - - - - - - - - - - - - CHAD k141_35063_3 223926.28809298 8.76e-188 521.0 COG3675@1|root,COG3675@2|Bacteria,1NICA@1224|Proteobacteria,1SHG9@1236|Gammaproteobacteria,1XT2J@135623|Vibrionales 135623|Vibrionales I Lipase (class 3) - - - - - - - - - - - - Lipase_3 k141_35063_4 1116375.VEJY3_19511 1.1e-40 135.0 2DNTE@1|root,32Z25@2|Bacteria,1QK3E@1224|Proteobacteria,1TI67@1236|Gammaproteobacteria,1XYGR@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_35063_5 1121405.dsmv_1219 2.04e-146 425.0 COG3021@1|root,COG3021@2|Bacteria,1MWFK@1224|Proteobacteria,42QIQ@68525|delta/epsilon subdivisions,2WM7F@28221|Deltaproteobacteria,2MJ1M@213118|Desulfobacterales 28221|Deltaproteobacteria S Endonuclease/Exonuclease/phosphatase family - - - - - - - - - - - - Exo_endo_phos k141_35063_6 870187.Thini_3940 1.56e-35 127.0 2DMJE@1|root,32RYR@2|Bacteria,1N7PS@1224|Proteobacteria,1S4DD@1236|Gammaproteobacteria,462Z7@72273|Thiotrichales 72273|Thiotrichales S Domain of unknown function (DUF4112) - - - - - - - - - - - - DUF4112 k141_17160_1 218284.CCDN010000001_gene1685 1.46e-88 286.0 COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,4HC3Y@91061|Bacilli,1ZCCY@1386|Bacillus 91061|Bacilli V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family yerP1 - - - - - - - - - - - ACR_tran k141_29063_2 42565.FP66_10395 2.09e-09 57.0 COG4638@1|root,COG4638@2|Bacteria,1MWXW@1224|Proteobacteria,1RQ0P@1236|Gammaproteobacteria,1XI6D@135619|Oceanospirillales 135619|Oceanospirillales P Rieske 2Fe-2S - - - ko:K00479 - - - - ko00000 - - - Rieske,Ring_hydroxyl_A k141_16014_1 1340434.AXVA01000005_gene4544 8.96e-29 112.0 COG0538@1|root,COG0538@2|Bacteria,1UHPE@1239|Firmicutes,4H9US@91061|Bacilli,1ZBWV@1386|Bacillus 91061|Bacilli C isocitrate icd - 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh k141_16014_2 935836.JAEL01000105_gene2387 3.36e-191 536.0 COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,4H9YE@91061|Bacilli,1ZBAY@1386|Bacillus 91061|Bacilli C Belongs to the citrate synthase family citZ - 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 - - - Citrate_synt k141_21963_1 218284.CCDN010000006_gene3613 1.11e-150 435.0 COG0696@1|root,COG0696@2|Bacteria,1TPM4@1239|Firmicutes,4HBTQ@91061|Bacilli,1ZAPE@1386|Bacillus 91061|Bacilli G Catalyzes the interconversion of 2-phosphoglycerate and gpmI GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030145,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0043937,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046537,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0050789,GO:0050793,GO:0051186,GO:0051188,GO:0055086,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.4.2.12 ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000 - - - Metalloenzyme,Phosphodiest,iPGM_N k141_23259_1 315730.BcerKBAB4_2708 3.71e-08 55.1 COG1514@1|root,COG1514@2|Bacteria,1VBG1@1239|Firmicutes,4IMER@91061|Bacilli,1ZJZC@1386|Bacillus 91061|Bacilli J 2'-5' RNA ligase superfamily - - - - - - - - - - - - 2_5_RNA_ligase2 k141_23259_2 545693.BMQ_3712 7.47e-19 78.6 COG1878@1|root,COG1878@2|Bacteria,1U21N@1239|Firmicutes,4IBIN@91061|Bacilli,1ZIKG@1386|Bacillus 91061|Bacilli S Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation - - - - - - - - - - - - - k141_1681_1 1453501.JELR01000001_gene2499 6.2e-16 76.3 COG1721@1|root,COG1721@2|Bacteria,1Q7RR@1224|Proteobacteria,1RNNP@1236|Gammaproteobacteria,466HG@72275|Alteromonadaceae 1236|Gammaproteobacteria S conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - - - - - - - - - - DUF58 k141_1681_2 1279017.AQYJ01000025_gene757 1.5e-209 582.0 COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,1RN5G@1236|Gammaproteobacteria,464XH@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0714 MoxR-like ATPases moxR - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 k141_13834_2 1279017.AQYJ01000019_gene1509 6.73e-45 153.0 COG4726@1|root,COG4726@2|Bacteria,1NK1B@1224|Proteobacteria,1SGXT@1236|Gammaproteobacteria 1236|Gammaproteobacteria NU Pilus assembly protein PilX - - - - - - - - - - - - PilX,PilX_N k141_11393_1 1294265.JCM21738_3347 1.19e-126 366.0 COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,4HA4E@91061|Bacilli,1ZB72@1386|Bacillus 91061|Bacilli P Belongs to the ABC transporter superfamily - - - ko:K02031 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - ABC_tran,oligo_HPY k141_5438_4 37659.JNLN01000001_gene1895 1.29e-19 90.5 COG1434@1|root,COG1434@2|Bacteria,1VA42@1239|Firmicutes,24HKK@186801|Clostridia,36HJ1@31979|Clostridiaceae 186801|Clostridia S DUF218 domain - - - - - - - - - - - - DUF218 k141_25657_1 218284.CCDN010000001_gene1401 2.33e-140 407.0 COG0006@1|root,COG0006@2|Bacteria,1V22K@1239|Firmicutes,4HTV2@91061|Bacilli,1ZNEY@1386|Bacillus 91061|Bacilli E Metallopeptidase family M24 - - - - - - - - - - - - - k141_27747_1 1042377.AFPJ01000009_gene244 2.64e-180 520.0 COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,1RMDA@1236|Gammaproteobacteria,46AV9@72275|Alteromonadaceae 1236|Gammaproteobacteria MU Outer membrane efflux protein - - - - - - - - - - - - OEP k141_27747_2 1279017.AQYJ01000025_gene677 1.62e-274 752.0 COG1960@1|root,COG1960@2|Bacteria,1MUK0@1224|Proteobacteria,1RNBX@1236|Gammaproteobacteria,463ZM@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1960 Acyl-CoA dehydrogenases gcdH - 1.3.8.6 ko:K00252 ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130 M00032 R02487,R02488,R10074 RC00052,RC00156 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_27747_3 1453501.JELR01000001_gene2165 1.06e-114 332.0 COG2860@1|root,COG2860@2|Bacteria,1RHQN@1224|Proteobacteria,1S5YY@1236|Gammaproteobacteria,466HB@72275|Alteromonadaceae 1236|Gammaproteobacteria S UPF0126 domain - - - - - - - - - - - - UPF0126 k141_27747_4 1279017.AQYJ01000025_gene679 2.51e-248 699.0 COG0596@1|root,COG0596@2|Bacteria,1R6KU@1224|Proteobacteria,1RNTQ@1236|Gammaproteobacteria,4692F@72275|Alteromonadaceae 1236|Gammaproteobacteria S TAP-like protein - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_4 k141_27747_5 1305737.JAFX01000001_gene2689 1.02e-153 446.0 COG2911@1|root,COG2911@2|Bacteria,4NHAF@976|Bacteroidetes,47T04@768503|Cytophagia 976|Bacteroidetes S COG NOG10142 non supervised orthologous group - - - - - - - - - - - - Porin_2 k141_27747_6 1177179.A11A3_08170 8.44e-156 448.0 COG2066@1|root,COG2066@2|Bacteria,1MWB5@1224|Proteobacteria,1RMY9@1236|Gammaproteobacteria,1XHZG@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the glutaminase family glsA - 3.5.1.2 ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 - R00256,R01579 RC00010,RC02798 ko00000,ko00001,ko01000 - - - Glutaminase k141_27747_7 196367.JNFG01000011_gene6139 5.15e-69 223.0 COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,2VHAX@28216|Betaproteobacteria,1K2GD@119060|Burkholderiaceae 28216|Betaproteobacteria P Sulfurtransferase sseA - 2.8.1.1,2.8.1.2 ko:K01011 ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122 - R01931,R03105,R03106 RC00214 ko00000,ko00001,ko01000 - - - Rhodanese k141_37359_1 1179226.AJXO01000005_gene1865 9.94e-13 76.6 COG0739@1|root,COG1196@1|root,COG3941@1|root,COG3953@1|root,COG5412@1|root,COG0739@2|Bacteria,COG1196@2|Bacteria,COG3941@2|Bacteria,COG3953@2|Bacteria,COG5412@2|Bacteria,1TQ28@1239|Firmicutes,4HAFE@91061|Bacilli,4GY27@90964|Staphylococcaceae 91061|Bacilli M Phage tail tape measure protein - - - - - - - - - - - - Peptidase_M23,PhageMin_Tail,SLT k141_24320_1 1294265.JCM21738_4195 3.48e-104 312.0 COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,4HA1P@91061|Bacilli,1ZC8I@1386|Bacillus 91061|Bacilli L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII dinB2 - - ko:K03502 - - - - ko00000,ko03400 - - - IMS,IMS_C,IMS_HHH k141_5439_1 204669.Acid345_1504 2.92e-59 198.0 COG2195@1|root,COG2195@2|Bacteria,3Y6CZ@57723|Acidobacteria 57723|Acidobacteria E Peptidase dimerisation domain - - - ko:K01270 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 k141_16015_1 1034347.CAHJ01000005_gene2480 3.09e-06 48.5 COG3973@1|root,COG3973@2|Bacteria,1TP39@1239|Firmicutes,4H9Y5@91061|Bacilli,1ZAWP@1386|Bacillus 91061|Bacilli L DNA helicase uvrD - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_19,UvrD-helicase,UvrD_C,UvrD_C_2 k141_16015_2 866895.HBHAL_1898 3.86e-99 298.0 COG0477@1|root,COG2814@2|Bacteria,1TR6I@1239|Firmicutes,4HBX6@91061|Bacilli,3NEE6@45667|Halobacillus 91061|Bacilli EGP Major Facilitator Superfamily tcaB - - ko:K07552 - - - - ko00000,ko02000 2.A.1.2 - - MFS_1 k141_23261_1 1121931.AUHG01000019_gene3055 1.55e-83 255.0 COG0702@1|root,COG0702@2|Bacteria,4NICI@976|Bacteroidetes,1IIU7@117743|Flavobacteriia 976|Bacteroidetes GM NmrA-like family - - - - - - - - - - - - NmrA k141_11545_9 1279017.AQYJ01000021_gene2898 2.8e-31 118.0 COG3147@1|root,COG3147@2|Bacteria,1NGE3@1224|Proteobacteria,1SCGC@1236|Gammaproteobacteria,46CSJ@72275|Alteromonadaceae 1236|Gammaproteobacteria S Sporulation related domain dedD - - ko:K03749 - - - - ko00000 - - - SPOR k141_23437_2 218284.CCDN010000003_gene2992 5.75e-72 230.0 COG1694@1|root,COG3956@2|Bacteria,1TPK1@1239|Firmicutes,4HA0A@91061|Bacilli,1ZAYB@1386|Bacillus 91061|Bacilli S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like yabN GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.66 ko:K02428,ko:K02499 ko00230,map00230 - R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000,ko03036 - - - MazG,TP_methylase k141_32675_2 218284.CCDN010000002_gene2132 7.61e-48 166.0 COG1574@1|root,COG1574@2|Bacteria,1TQ6G@1239|Firmicutes,4H9T6@91061|Bacilli,1ZC1J@1386|Bacillus 91061|Bacilli S Amidohydrolase family ytcJ - - - - - - - - - - - Amidohydro_3 k141_35288_2 1116375.VEJY3_06585 2.98e-220 608.0 COG2040@1|root,COG2040@2|Bacteria,1MUXU@1224|Proteobacteria,1SBT6@1236|Gammaproteobacteria,1Y11R@135623|Vibrionales 135623|Vibrionales E Homocysteine S-methyltransferase - - - - - - - - - - - - S-methyl_trans k141_35288_3 223926.28809575 5.92e-40 134.0 2EV9I@1|root,31NH5@2|Bacteria,1QK80@1224|Proteobacteria,1TIBA@1236|Gammaproteobacteria,1XYT6@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_35288_4 1116375.VEJY3_06515 1.48e-69 210.0 2AWA5@1|root,31N5P@2|Bacteria,1QJX1@1224|Proteobacteria,1THYZ@1236|Gammaproteobacteria,1XXYH@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_35288_5 1116375.VEJY3_06510 7.25e-136 387.0 COG0551@1|root,COG0551@2|Bacteria,1RJ5B@1224|Proteobacteria,1S349@1236|Gammaproteobacteria,1XT3J@135623|Vibrionales 135623|Vibrionales L Zn-finger domain associated with topoisomerase type I - - - - - - - - - - - - DUF2726 k141_35288_6 1280001.BAOA01000034_gene2221 1.19e-133 380.0 COG2176@1|root,COG2176@2|Bacteria,1QUHH@1224|Proteobacteria,1T1Z7@1236|Gammaproteobacteria,1XUWD@135623|Vibrionales 135623|Vibrionales L COG2176 DNA polymerase III, alpha subunit (gram-positive type) - - 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - RNase_T k141_836_1 1042377.AFPJ01000052_gene1564 2.31e-101 309.0 COG2853@1|root,COG2853@2|Bacteria,1MVX0@1224|Proteobacteria,1RNPS@1236|Gammaproteobacteria,466E2@72275|Alteromonadaceae 1236|Gammaproteobacteria M Surface lipoprotein vacJ - - ko:K04754 - - - - ko00000 - - - MlaA k141_12797_1 1134474.O59_000544 6.85e-06 57.4 COG3866@1|root,COG5276@1|root,COG3866@2|Bacteria,COG5276@2|Bacteria,1QPFF@1224|Proteobacteria,1RQEM@1236|Gammaproteobacteria,1FHZ2@10|Cellvibrio 1236|Gammaproteobacteria G Pectate lyase - - - - - - - - - - - - CBM_35,CBM_5_12_2,CBM_6,Pec_lyase_C,RicinB_lectin_2 k141_22089_1 218284.CCDN010000002_gene2942 6.4e-197 550.0 COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,4HBED@91061|Bacilli,1ZBXY@1386|Bacillus 91061|Bacilli EP COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components dppB - - ko:K02033 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 k141_24500_3 218284.CCDN010000001_gene158 3.99e-160 451.0 COG0561@1|root,COG0561@2|Bacteria,1TSZZ@1239|Firmicutes,4HB54@91061|Bacilli,1ZBY4@1386|Bacillus 91061|Bacilli S hydrolases of the HAD superfamily ykrA - - - - - - - - - - - Hydrolase_3,S6PP k141_16149_1 754476.Q7A_1415 1.61e-49 176.0 COG3307@1|root,COG3307@2|Bacteria,1MV4S@1224|Proteobacteria,1S15Z@1236|Gammaproteobacteria,461NP@72273|Thiotrichales 72273|Thiotrichales M O-antigen ligase like membrane protein - - - - - - - - - - - - - k141_30255_1 218284.CCDN010000002_gene2083 4.69e-108 322.0 COG1541@1|root,COG1541@2|Bacteria,1TQA1@1239|Firmicutes,4HAU0@91061|Bacilli,1ZBRF@1386|Bacillus 91061|Bacilli H Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) paaK - 6.2.1.30 ko:K01912 ko00360,ko01120,ko05111,map00360,map01120,map05111 - R02539 RC00004,RC00014 ko00000,ko00001,ko01000 - - - AMP-binding,AMP-binding_C_2 k141_20833_1 1294265.JCM21738_3914 8.45e-119 341.0 COG1182@1|root,COG1182@2|Bacteria,1UZBY@1239|Firmicutes,4HB1Z@91061|Bacilli,1ZD4D@1386|Bacillus 91061|Bacilli I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity azoR - - ko:K01118 - - - - ko00000,ko01000 - - - Flavodoxin_2 k141_29197_1 1279017.AQYJ01000028_gene2418 5.16e-78 241.0 COG1716@1|root,COG1716@2|Bacteria,1REM9@1224|Proteobacteria,1S46E@1236|Gammaproteobacteria 1236|Gammaproteobacteria T COG1716 FOG FHA domain - - - - - - - - - - - - FHA k141_29197_2 1453501.JELR01000002_gene500 5.8e-104 309.0 COG1846@1|root,COG1846@2|Bacteria,1RF8X@1224|Proteobacteria,1S4RW@1236|Gammaproteobacteria,466UV@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG1846 Transcriptional regulators - - - - - - - - - - - - MarR k141_36218_1 218284.CCDN010000001_gene545 7.03e-20 84.0 COG4508@1|root,COG4508@2|Bacteria,1V6PI@1239|Firmicutes,4HJBB@91061|Bacilli,1ZGXN@1386|Bacillus 91061|Bacilli S dUTPase - - - - - - - - - - - - dUTPase_2 k141_36218_2 218284.CCDN010000001_gene544 3.62e-68 209.0 29RHG@1|root,30CKE@2|Bacteria,1V4BT@1239|Firmicutes,4HIQA@91061|Bacilli,1ZH08@1386|Bacillus 91061|Bacilli S Sigma-w pathway protein YsdB ysdB - - - - - - - - - - - - k141_7766_1 1385510.N781_11570 1.91e-32 117.0 COG3576@1|root,COG3576@2|Bacteria,1VW5G@1239|Firmicutes,4IK0W@91061|Bacilli,2YBJQ@289201|Pontibacillus 91061|Bacilli S Pyridoxamine 5'-phosphate oxidase - - - - - - - - - - - - Putative_PNPOx k141_7766_3 218284.CCDN010000002_gene2692 3.27e-23 94.7 COG0491@1|root,COG0491@2|Bacteria,1U98Y@1239|Firmicutes,4HDNC@91061|Bacilli,1ZFJX@1386|Bacillus 91061|Bacilli S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B k141_11546_1 218284.CCDN010000002_gene2070 1.18e-175 512.0 COG1199@1|root,COG1199@2|Bacteria,1TPNB@1239|Firmicutes,4HD6T@91061|Bacilli,1ZAUN@1386|Bacillus 91061|Bacilli KL DEAD_2 uvrB3 - 3.1.12.1 ko:K07464 - - - - ko00000,ko01000,ko02048 - - - DEAD,DEAD_2,HBB,Helicase_C_2,PDDEXK_1 k141_14016_1 42565.FP66_09525 2.41e-23 97.8 COG1061@1|root,COG1061@2|Bacteria,1MV9F@1224|Proteobacteria,1RNAN@1236|Gammaproteobacteria,1XH5K@135619|Oceanospirillales 135619|Oceanospirillales L helicase superfamily c-terminal domain - - - ko:K19789 - - - - ko00000,ko03400 - - - Helicase_C,ResIII k141_18710_1 218284.CCDN010000001_gene113 1.94e-50 161.0 2EG6V@1|root,339YR@2|Bacteria,1VPN6@1239|Firmicutes,4HREE@91061|Bacilli,1ZIWK@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_24501_1 1294265.JCM21738_2962 7.39e-70 216.0 COG1116@1|root,COG1116@2|Bacteria,1TRM6@1239|Firmicutes,4HBZ6@91061|Bacilli,1ZC33@1386|Bacillus 91061|Bacilli P ABC transporter ytlC - 3.6.3.36 ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 M00188,M00435,M00436 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.16,3.A.1.17,3.A.1.17.1,3.A.1.17.2,3.A.1.17.4 - - ABC_tran k141_24501_2 1294265.JCM21738_2963 7.69e-76 234.0 COG0600@1|root,COG0600@2|Bacteria,1TR6A@1239|Firmicutes,4HARB@91061|Bacilli,1ZD96@1386|Bacillus 91061|Bacilli P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component ytlD GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02050 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - BPD_transp_1 k141_837_1 218284.CCDN010000002_gene2917 5.57e-95 278.0 COG2259@1|root,COG2259@2|Bacteria,1V4ER@1239|Firmicutes,4HGZN@91061|Bacilli,1ZEVR@1386|Bacillus 91061|Bacilli S DoxX - - 1.8.5.2 ko:K16937 ko00920,ko01120,map00920,map01120 - R07177 - ko00000,ko00001,ko01000 3.D.4.9 - - DoxX k141_9119_1 1200792.AKYF01000013_gene4251 5.53e-05 45.4 COG2211@1|root,COG2211@2|Bacteria,1TR4D@1239|Firmicutes,4HDCY@91061|Bacilli,26VTF@186822|Paenibacillaceae 91061|Bacilli G of the major facilitator superfamily yjbB - - - - - - - - - - - MFS_1 k141_7767_1 868595.Desca_1649 5.98e-19 88.6 COG1484@1|root,COG1484@2|Bacteria,1V5FC@1239|Firmicutes,25MEZ@186801|Clostridia,2665P@186807|Peptococcaceae 186801|Clostridia L IstB-like ATP binding protein - - - ko:K02315 - - - - ko00000,ko03032 - - - IstB_IS21 k141_5615_1 218284.CCDN010000002_gene2849 1.43e-138 400.0 COG0697@1|root,COG0697@2|Bacteria,1TRKE@1239|Firmicutes,4HF69@91061|Bacilli,1ZQ3B@1386|Bacillus 91061|Bacilli EG EamA-like transporter family - - - - - - - - - - - - EamA k141_35290_1 218284.CCDN010000002_gene2671 2.93e-71 218.0 COG4430@1|root,COG4430@2|Bacteria,1UYP9@1239|Firmicutes,4HDZD@91061|Bacilli,1ZDB7@1386|Bacillus 91061|Bacilli S Bacteriocin-protection, YdeI or OmpD-Associated ydeI - - - - - - - - - - - DUF1801,OmdA k141_35290_2 218284.CCDN010000002_gene2670 2.18e-83 246.0 COG5646@1|root,COG5646@2|Bacteria,1V6QT@1239|Firmicutes,4HIUI@91061|Bacilli,1ZFK6@1386|Bacillus 91061|Bacilli S Domain of unknown function (DU1801) frataxin - - ko:K05937 - - - - ko00000 - - - DUF1801 k141_11547_1 935848.JAEN01000012_gene3960 1.91e-128 370.0 COG1129@1|root,COG1129@2|Bacteria,1MVNR@1224|Proteobacteria,2TTN8@28211|Alphaproteobacteria,2PVTS@265|Paracoccus 28211|Alphaproteobacteria G ATPases associated with a variety of cellular activities frcA - - ko:K10554 ko02010,map02010 M00218 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.7 - - ABC_tran k141_25828_1 218284.CCDN010000005_gene3201 1.47e-125 372.0 COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HA2G@91061|Bacilli,1ZBE5@1386|Bacillus 91061|Bacilli IQ Activates fatty acids by binding to coenzyme A lcfB_2 - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding,AMP-binding_C k141_14017_1 393595.ABO_0939 2.46e-17 87.0 COG2244@1|root,COG2244@2|Bacteria,1MWKV@1224|Proteobacteria,1S4AZ@1236|Gammaproteobacteria,1XQ6A@135619|Oceanospirillales 135619|Oceanospirillales S Polysaccharide biosynthesis protein - - - - - - - - - - - - Polysacc_synt,Polysacc_synt_C k141_11548_1 545693.BMQ_1147 4.99e-96 287.0 COG2084@1|root,COG2084@2|Bacteria,1TR4F@1239|Firmicutes,4H9MA@91061|Bacilli,1ZBSG@1386|Bacillus 91061|Bacilli I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases garR - 1.1.1.60 ko:K00042 ko00630,ko01100,map00630,map01100 - R01745,R01747 RC00099 ko00000,ko00001,ko01000 - - - NAD_binding_11,NAD_binding_2 k141_12798_1 314345.SPV1_03948 1.61e-30 123.0 COG0243@1|root,COG0243@2|Bacteria 2|Bacteria C molybdopterin cofactor binding qrcB - - - - - - - - - - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding k141_23440_2 1294265.JCM21738_2090 5.39e-133 378.0 COG0491@1|root,COG0491@2|Bacteria,1V6FA@1239|Firmicutes,4HHRQ@91061|Bacilli,1ZC72@1386|Bacillus 91061|Bacilli S COG0491 Zn-dependent hydrolases, including glyoxylases yqgX - 3.1.2.6 ko:K01069 ko00620,map00620 - R01736 RC00004,RC00137 ko00000,ko00001,ko01000 - - - Lactamase_B k141_3001_1 42565.FP66_01070 4.07e-194 541.0 COG3138@1|root,COG3138@2|Bacteria,1MWHC@1224|Proteobacteria,1RMXG@1236|Gammaproteobacteria,1XHNI@135619|Oceanospirillales 135619|Oceanospirillales E arginine N-succinyltransferase - - 2.3.1.109 ko:K00673 ko00330,ko01100,map00330,map01100 - R00832 RC00004,RC00064 ko00000,ko00001,ko01000 - - - AstA k141_3001_2 42565.FP66_01075 1.48e-55 182.0 COG3138@1|root,COG3138@2|Bacteria,1NMVM@1224|Proteobacteria,1RSGX@1236|Gammaproteobacteria,1XIHZ@135619|Oceanospirillales 135619|Oceanospirillales E arginine N-succinyltransferase aruF - 2.3.1.109 ko:K00673 ko00330,ko01100,map00330,map01100 - R00832 RC00004,RC00064 ko00000,ko00001,ko01000 - - - AstA k141_838_2 205922.Pfl01_4046 2.12e-16 80.9 COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,1RQ7S@1236|Gammaproteobacteria,1YSXN@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria E DegT/DnrJ/EryC1/StrS aminotransferase family - - 2.6.1.33 ko:K20429 - - R02773 RC00006,RC00781 ko00000,ko01000 - - - DegT_DnrJ_EryC1 k141_22093_1 1042377.AFPJ01000034_gene2367 1.97e-27 109.0 COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,1RP25@1236|Gammaproteobacteria,465HJ@72275|Alteromonadaceae 1236|Gammaproteobacteria M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) murD GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008764,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - iAPECO1_1312.APECO1_1898,iECNA114_1301.ECNA114_0081,iECOK1_1307.ECOK1_0089,iECP_1309.ECP_0090,iECS88_1305.ECS88_0091,iECSF_1327.ECSF_0098,iLF82_1304.LF82_1418,iNRG857_1313.NRG857_00450,iUMN146_1321.UM146_23225,iUTI89_1310.UTI89_C0097 Mur_ligase_C,Mur_ligase_M k141_14888_1 1123236.KB899383_gene2663 6.67e-105 318.0 COG1069@1|root,COG1069@2|Bacteria,1MY11@1224|Proteobacteria,1RP3F@1236|Gammaproteobacteria,4662E@72275|Alteromonadaceae 1236|Gammaproteobacteria G FGGY family of carbohydrate kinases, N-terminal domain araB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008741,GO:0009056,GO:0009058,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019321,GO:0019323,GO:0019566,GO:0019568,GO:0019569,GO:0019572,GO:0019637,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046365,GO:0046373,GO:0046835,GO:0051167,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901159,GO:1901575,GO:1901576 2.7.1.16 ko:K00853 ko00040,ko01100,map00040,map01100 - R01526,R02439 RC00002,RC00538 ko00000,ko00001,ko01000 - - iBWG_1329.BWG_0059,iECH74115_1262.ECH74115_0068,iECSP_1301.ECSP_0067,iECs_1301.ECs0067,iG2583_1286.G2583_0066,iPC815.YPO2254,iZ_1308.Z0072 FGGY_C,FGGY_N k141_27170_1 1279017.AQYJ01000021_gene2947 1.3e-15 80.5 COG1714@1|root,COG2214@1|root,COG1714@2|Bacteria,COG2214@2|Bacteria,1NGQY@1224|Proteobacteria,1S3RD@1236|Gammaproteobacteria 1236|Gammaproteobacteria O DnaJ molecular chaperone homology domain - - - ko:K07126 - - - - ko00000 - - - RDD k141_27170_2 1453501.JELR01000001_gene1887 1.04e-208 592.0 COG0443@1|root,COG0443@2|Bacteria,1MUR1@1224|Proteobacteria,1RR7P@1236|Gammaproteobacteria,469ME@72275|Alteromonadaceae 1236|Gammaproteobacteria O MreB/Mbl protein hscC GO:0003674,GO:0003824,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111 - ko:K04045 - - - - ko00000,ko03110 1.A.33 - iSFV_1184.SFV_0676 HSP70,MreB_Mbl k141_14041_1 379066.GAU_0850 2.62e-60 193.0 COG0250@1|root,COG0250@2|Bacteria,1ZSS2@142182|Gemmatimonadetes 142182|Gemmatimonadetes K Participates in transcription elongation, termination and antitermination nusG - - ko:K02601 - - - - ko00000,ko03009,ko03021 - - - NusG k141_14041_2 926561.KB900620_gene3214 3.04e-11 59.7 COG0690@1|root,COG0690@2|Bacteria,1VK48@1239|Firmicutes,24UI4@186801|Clostridia,3WAYQ@53433|Halanaerobiales 186801|Clostridia U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation secE - - ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecE k141_9148_1 1453501.JELR01000002_gene856 3.58e-105 320.0 COG1040@1|root,COG1040@2|Bacteria,1REX9@1224|Proteobacteria,1S568@1236|Gammaproteobacteria,4671D@72275|Alteromonadaceae 1236|Gammaproteobacteria S competence protein - - - - - - - - - - - - - k141_9148_2 1453501.JELR01000002_gene856 5.48e-43 161.0 COG1040@1|root,COG1040@2|Bacteria,1REX9@1224|Proteobacteria,1S568@1236|Gammaproteobacteria,4671D@72275|Alteromonadaceae 1236|Gammaproteobacteria S competence protein - - - - - - - - - - - - - k141_9148_4 1279017.AQYJ01000020_gene1277 9.27e-51 176.0 COG1566@1|root,COG1566@2|Bacteria,1RJ3I@1224|Proteobacteria,1S7BS@1236|Gammaproteobacteria,46ACD@72275|Alteromonadaceae 1236|Gammaproteobacteria V Protein of unknown function (DUF3667) - - - - - - - - - - - - DUF3667 k141_29228_1 218284.CCDN010000001_gene1341 1.12e-125 376.0 COG4548@1|root,COG4548@2|Bacteria,1TPW1@1239|Firmicutes,4HCPJ@91061|Bacilli,1ZD6R@1386|Bacillus 91061|Bacilli P Von Willebrand factor yojO - - - - - - - - - - - CobT_C,VWA k141_17322_1 42565.FP66_02450 8.1e-136 404.0 COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,1RNJI@1236|Gammaproteobacteria,1XIU4@135619|Oceanospirillales 135619|Oceanospirillales L Unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present uvrD - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C k141_1810_1 1453501.JELR01000002_gene505 1.89e-134 392.0 COG0265@1|root,COG0265@2|Bacteria,1NXB0@1224|Proteobacteria,1RRAD@1236|Gammaproteobacteria,465AC@72275|Alteromonadaceae 1236|Gammaproteobacteria O Trypsin-like peptidase domain - - - - - - - - - - - - Trypsin_2 k141_36237_1 1279017.AQYJ01000024_gene1075 5.19e-56 194.0 COG3107@1|root,COG3107@2|Bacteria,1MUHR@1224|Proteobacteria,1RXX4@1236|Gammaproteobacteria,465I7@72275|Alteromonadaceae 1236|Gammaproteobacteria M (Lipo)protein lpoA GO:0000270,GO:0003674,GO:0005575,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009279,GO:0009987,GO:0016020,GO:0019867,GO:0030203,GO:0030234,GO:0030312,GO:0030313,GO:0031241,GO:0031975,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044425,GO:0044462,GO:0044464,GO:0050790,GO:0065007,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0098552,GO:0098772,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 - ko:K07121 - - - - ko00000 - - - LppC k141_19772_1 218284.CCDN010000002_gene2923 7.96e-11 60.8 COG0300@1|root,COG0300@2|Bacteria,1U5VD@1239|Firmicutes,4HES8@91061|Bacilli,1ZDY5@1386|Bacillus 91061|Bacilli S Enoyl-(Acyl carrier protein) reductase - - - ko:K07124 - - - - ko00000 - - - adh_short k141_31424_1 218284.CCDN010000005_gene3367 0.0 950.0 COG5002@1|root,COG5002@2|Bacteria,1VUBP@1239|Firmicutes,4HUPW@91061|Bacilli,1ZS15@1386|Bacillus 91061|Bacilli T Histidine kinase kinE - 2.7.13.3 ko:K13533 ko02020,map02020 M00485 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9 k141_22119_2 218284.CCDN010000001_gene1513 3.73e-72 238.0 COG1112@1|root,COG1112@2|Bacteria,1UNF1@1239|Firmicutes,4IPKF@91061|Bacilli,1ZDR8@1386|Bacillus 91061|Bacilli L COG1112 Superfamily I DNA and RNA helicases and helicase subunits - - - - - - - - - - - - AAA_11,AAA_12 k141_4280_2 218284.CCDN010000001_gene1149 1.09e-26 103.0 2EGVD@1|root,33AMM@2|Bacteria,1VKVK@1239|Firmicutes,4HRYS@91061|Bacilli,1ZITC@1386|Bacillus 91061|Bacilli - - ypoC - - - - - - - - - - - - k141_18734_2 218284.CCDN010000001_gene4 5.14e-167 470.0 COG4974@1|root,COG4974@2|Bacteria,1TPQB@1239|Firmicutes,4HARA@91061|Bacilli,1ZB91@1386|Bacillus 91061|Bacilli L tyrosine recombinase XerC xerC - - ko:K03733,ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase k141_14042_1 218284.CCDN010000001_gene77 1.69e-94 279.0 29ECG@1|root,301AF@2|Bacteria,1UY4W@1239|Firmicutes,4HDX6@91061|Bacilli,1ZAV2@1386|Bacillus 91061|Bacilli M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR spoIIGA GO:0003674,GO:0003824,GO:0004175,GO:0004190,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016020,GO:0016021,GO:0016787,GO:0019538,GO:0031224,GO:0031226,GO:0043170,GO:0043621,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0070001,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 - ko:K06383 - - - - ko00000,ko01000,ko01002 - - - Peptidase_U4 k141_16162_1 1042377.AFPJ01000002_gene514 1.16e-114 332.0 COG0204@1|root,COG0204@2|Bacteria,1RJMS@1224|Proteobacteria,1S71V@1236|Gammaproteobacteria,467SS@72275|Alteromonadaceae 1236|Gammaproteobacteria I Phosphate acyltransferases - - - - - - - - - - - - Acyltransferase k141_12810_1 1453501.JELR01000002_gene1242 6.45e-108 313.0 COG3124@1|root,COG3124@2|Bacteria,1MZ59@1224|Proteobacteria,1S9IZ@1236|Gammaproteobacteria,467N3@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria acpH GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008081,GO:0008150,GO:0008152,GO:0008610,GO:0008770,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0016788,GO:0019752,GO:0032787,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:0140096,GO:1901576 3.1.4.14 ko:K08682 ko00770,map00770 - R01623 - ko00000,ko00001,ko01000 - - iAPECO1_1312.APECO1_1606,iE2348C_1286.E2348C_0339,iECNA114_1301.ECNA114_0381,iECOK1_1307.ECOK1_0384,iECS88_1305.ECS88_0399,iECSF_1327.ECSF_0364,iPC815.YPO3193,iUMN146_1321.UM146_15340,iUTI89_1310.UTI89_C0426 ACP_PD k141_29229_1 218284.CCDN010000002_gene1983 8.17e-170 482.0 COG0026@1|root,COG0026@2|Bacteria,1TQCD@1239|Firmicutes,4H9M5@91061|Bacilli,1ZB8P@1386|Bacillus 91061|Bacilli F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) purK GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 6.3.4.18 ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07404 RC01927 ko00000,ko00001,ko00002,ko01000 - - - 2-Hacid_dh_C,ATP-grasp k141_24535_2 1279017.AQYJ01000023_gene3161 2.01e-144 424.0 COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,1RNI4@1236|Gammaproteobacteria,4664Q@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1008 NADH ubiquinone oxidoreductase subunit 4 (chain M) nuoM - 1.6.5.3 ko:K00342 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_M k141_5632_1 1042377.AFPJ01000038_gene1100 4.12e-215 612.0 COG4774@1|root,COG4774@2|Bacteria,1NMCN@1224|Proteobacteria,1T3TQ@1236|Gammaproteobacteria,46DC7@72275|Alteromonadaceae 1236|Gammaproteobacteria P TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_855_1 441769.ABFU01000049_gene3703 1.27e-33 131.0 COG1807@1|root,COG1807@2|Bacteria,1TR0R@1239|Firmicutes,4HBI2@91061|Bacilli,1ZET9@1386|Bacillus 91061|Bacilli M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - - - - - - - - - - PMT_2 k141_14919_1 574375.BAGA_14555 1.55e-13 72.0 COG1173@1|root,COG1173@2|Bacteria,1V21B@1239|Firmicutes,4HJ5Y@91061|Bacilli,1ZFPK@1386|Bacillus 91061|Bacilli EP ABC transporter (permease) - - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 k141_27172_1 1380394.JADL01000009_gene3188 1.11e-84 266.0 COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,2TS6F@28211|Alphaproteobacteria,2JQ3D@204441|Rhodospirillales 204441|Rhodospirillales O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function radA - - ko:K04485 - - - - ko00000,ko03400 - - - AAA_25,ATPase,ChlI k141_19773_1 42565.FP66_13440 3.39e-102 302.0 COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,1RMKP@1236|Gammaproteobacteria,1XH40@135619|Oceanospirillales 135619|Oceanospirillales J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs truB - 5.4.99.25 ko:K03177 - - - - ko00000,ko01000,ko03016 - - - TruB-C_2,TruB_C_2,TruB_N k141_19773_2 42565.FP66_13435 3.4e-64 197.0 COG0858@1|root,COG0858@2|Bacteria,1MZPE@1224|Proteobacteria,1S9AF@1236|Gammaproteobacteria,1XKKG@135619|Oceanospirillales 135619|Oceanospirillales J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA rbfA - - ko:K02834 - - - - ko00000,ko03009 - - - RBFA k141_18735_1 414996.IL38_18215 2.55e-25 108.0 COG1473@1|root,COG1473@2|Bacteria,2I2WA@201174|Actinobacteria 201174|Actinobacteria S amidohydrolase - - - - - - - - - - - - GCS2 k141_20850_3 199310.c0987 3.32e-91 286.0 COG0687@1|root,COG0687@2|Bacteria,1MUYW@1224|Proteobacteria,1RM7W@1236|Gammaproteobacteria,3XN5N@561|Escherichia 1236|Gammaproteobacteria P Required for the activity of the bacterial periplasmic transport system of putrescine potF GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015846,GO:0015847,GO:0019808,GO:0019810,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043167,GO:0043169,GO:0044464,GO:0051179,GO:0051234,GO:0070405,GO:0071702,GO:0071705 - ko:K11073 ko02010,map02010 M00300 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.2 - iB21_1397.B21_00865,iECBD_1354.ECBD_2740,iECB_1328.ECB_00859,iECD_1391.ECD_00859,iEcHS_1320.EcHS_A0957,iEcolC_1368.EcolC_2742,iPC815.YPO1331 SBP_bac_8 k141_11573_1 585506.HMPREF0877_0771 9.77e-06 47.8 COG0834@1|root,COG0834@2|Bacteria,1UFZS@1239|Firmicutes,4HD9I@91061|Bacilli,4AX3Y@81850|Leuconostocaceae 91061|Bacilli ET Bacterial periplasmic substrate-binding proteins fliY - - ko:K02030,ko:K02424 ko02010,map02010 M00234,M00236 - - ko00000,ko00001,ko00002,ko02000,ko02035 3.A.1.3,3.A.1.3.10,3.A.1.3.14 - - SBP_bac_3 k141_11573_2 1294265.JCM21738_3951 2.78e-144 408.0 COG0765@1|root,COG0765@2|Bacteria,1TS6X@1239|Firmicutes,4HC03@91061|Bacilli,1ZCI9@1386|Bacillus 91061|Bacilli E Binding-protein-dependent transport system inner membrane component - - - ko:K02029 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 k141_11573_3 1294265.JCM21738_3952 1.97e-74 228.0 COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4H9WY@91061|Bacilli,1ZB2E@1386|Bacillus 91061|Bacilli E COG1126 ABC-type polar amino acid transport system, ATPase component glnQ2 - 3.6.3.21 ko:K02028 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran k141_25970_1 218284.CCDN010000002_gene2792 5.82e-105 319.0 COG1305@1|root,COG1305@2|Bacteria,1UZ8N@1239|Firmicutes,4IPXF@91061|Bacilli 91061|Bacilli E Transglutaminase-like domain - - - - - - - - - - - - Transglut_core k141_30345_1 626887.J057_16155 4.29e-48 157.0 2E4J2@1|root,32ZE4@2|Bacteria,1N7YM@1224|Proteobacteria,1S4GF@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF3775) - - - - - - - - - - - - DUF3775 k141_30345_2 498211.CJA_3229 3.13e-26 101.0 2E3B5@1|root,32YAP@2|Bacteria,1N7KQ@1224|Proteobacteria,1SF5B@1236|Gammaproteobacteria,1FH89@10|Cellvibrio 1236|Gammaproteobacteria S Protein of unknown function (DUF2721) - - - - - - - - - - - - DUF2721 k141_22321_2 316275.VSAL_I0244 8.35e-199 552.0 COG1209@1|root,COG1209@2|Bacteria,1MU0X@1224|Proteobacteria,1RMTR@1236|Gammaproteobacteria,1XU3P@135623|Vibrionales 135623|Vibrionales H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis rmlA - 2.7.7.24 ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 M00793 R02328 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase k141_29346_1 406124.ACPC01000012_gene1027 8.11e-64 200.0 COG2345@1|root,COG2345@2|Bacteria,1V23D@1239|Firmicutes,4HGV8@91061|Bacilli,1ZM3M@1386|Bacillus 91061|Bacilli K Sigma-54 dependent transcriptional regulator - - - - - - - - - - - - - k141_9327_1 574375.BAGA_27030 2.77e-18 84.7 COG0477@1|root,COG2814@2|Bacteria,1TRP1@1239|Firmicutes,4HE9U@91061|Bacilli,1ZQ90@1386|Bacillus 91061|Bacilli EGP Major facilitator superfamily - - - ko:K05548 - - - - ko00000,ko02000 2.A.1.15 - - MFS_1,MFS_4,Sugar_tr k141_9327_2 1118054.CAGW01000053_gene1388 4.87e-21 87.8 COG0431@1|root,COG0431@2|Bacteria,1TPW6@1239|Firmicutes,4HBP2@91061|Bacilli,26WQV@186822|Paenibacillaceae 91061|Bacilli S NADPH-dependent FMN reductase - - 1.5.1.38,1.5.1.45 ko:K00299,ko:K16902 ko00380,ko00740,ko00920,ko01100,map00380,map00740,map00920,map01100 - R05706,R07210,R09517,R09520,R09748,R10206 RC00046,RC00126,RC01779,RC02556 ko00000,ko00001,ko01000 - - - FMN_red k141_24642_1 94122.Shewana3_2919 2.19e-215 612.0 COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,1S0X9@1236|Gammaproteobacteria,2QBEN@267890|Shewanellaceae 1236|Gammaproteobacteria L Helix-hairpin-helix containing domain VPA1266 - 3.1.11.5 ko:K03581 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_30,HHH_4,UvrD_C_2,Viral_helicase1 k141_24642_2 223926.28809927 8.66e-70 211.0 2FCJ4@1|root,344NF@2|Bacteria,1P33Y@1224|Proteobacteria,1SRGJ@1236|Gammaproteobacteria,1XXZD@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_24642_3 223926.28809926 1.22e-294 811.0 COG3182@1|root,COG3182@2|Bacteria,1MX8C@1224|Proteobacteria,1RSDV@1236|Gammaproteobacteria,1XU3U@135623|Vibrionales 135623|Vibrionales S Most likely function alternative not yet resolved - - - - - - - - - - - - PepSY,PepSY_TM k141_24642_4 1029823.AFIE01000001_gene2102 4.91e-224 627.0 COG0641@1|root,COG0641@2|Bacteria,1MX3M@1224|Proteobacteria,1RN4R@1236|Gammaproteobacteria,3NQH9@468|Moraxellaceae 1236|Gammaproteobacteria C Radical SAM superfamily - - - ko:K06871 - - - - ko00000 - - - Fer4_12,Radical_SAM,SPASM k141_24642_5 382464.ABSI01000011_gene2609 2.1e-135 407.0 COG3119@1|root,COG3119@2|Bacteria,46UET@74201|Verrucomicrobia,2IU4V@203494|Verrucomicrobiae 203494|Verrucomicrobiae P C-terminal region of aryl-sulfatase - - - - - - - - - - - - Sulfatase,Sulfatase_C k141_24642_7 1415755.JQLV01000001_gene904 1.69e-100 306.0 28KV1@1|root,2ZABP@2|Bacteria,1QVKA@1224|Proteobacteria 1224|Proteobacteria S Fusaric acid resistance protein-like - - - - - - - - - - - - DUF2955,FUSC_2 k141_24642_8 1525715.IX54_00555 1.13e-90 284.0 COG1566@1|root,COG1566@2|Bacteria,1MU7I@1224|Proteobacteria,2TS39@28211|Alphaproteobacteria,2PU59@265|Paracoccus 28211|Alphaproteobacteria V Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - ko:K03543,ko:K15549 - M00701 - - ko00000,ko00002,ko02000 8.A.1.1,8.A.1.1.3 - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 k141_24642_9 97139.C824_00816 2.51e-84 273.0 COG2211@1|root,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,24ABB@186801|Clostridia,36E3W@31979|Clostridiaceae 186801|Clostridia G transporter gph - - ko:K03292 - - - - ko00000 2.A.2 - - MFS_2 k141_24642_10 1280688.AUJB01000012_gene2576 6.88e-146 441.0 COG1472@1|root,COG1472@2|Bacteria,1TP63@1239|Firmicutes,24YIP@186801|Clostridia,3NH2P@46205|Pseudobutyrivibrio 186801|Clostridia G Glycosyl hydrolase family 3 N terminal domain - - 3.2.1.52 ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 M00628 R00022,R05963,R07809,R07810,R10831 RC00049 ko00000,ko00001,ko00002,ko01000 - - - Glyco_hydro_3 k141_24642_11 1121105.ATXL01000014_gene1782 4.56e-54 179.0 COG0637@1|root,COG0637@2|Bacteria,1V389@1239|Firmicutes,4HGHQ@91061|Bacilli,4B6RT@81852|Enterococcaceae 91061|Bacilli S Haloacid dehalogenase-like hydrolase pgmB GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0008150,GO:0008152,GO:0008801,GO:0016853,GO:0016866,GO:0016868,GO:0043167,GO:0043169,GO:0044238,GO:0046872,GO:0071704 5.4.2.6 ko:K01838 ko00500,map00500 - R02728,R11310 RC00408 ko00000,ko00001,ko01000 - - - HAD_2 k141_24642_12 1506583.JQJY01000007_gene4190 1.22e-70 248.0 COG3525@1|root,COG3525@2|Bacteria,4NE08@976|Bacteroidetes,1HXU1@117743|Flavobacteriia,2NSHE@237|Flavobacterium 976|Bacteroidetes G Pfam Glycosyl hydrolase family 20, catalytic domain - - 3.2.1.52 ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 M00079 R00022,R06004,R11316 RC00049 ko00000,ko00001,ko00002,ko01000,ko03110 - GH20 - CHB_HEX_C_1,F5_F8_type_C,Fn3_assoc,Glyco_hydro_20,Glyco_hydro_20b,PA14 k141_24642_14 1515746.HR45_16030 3.55e-179 503.0 COG0583@1|root,COG0583@2|Bacteria,1MU2E@1224|Proteobacteria,1S06P@1236|Gammaproteobacteria 1236|Gammaproteobacteria K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate k141_24642_15 1515746.HR45_16045 1.09e-240 665.0 COG1979@1|root,COG1979@2|Bacteria,1QUBJ@1224|Proteobacteria,1RP7C@1236|Gammaproteobacteria,2Q92Z@267890|Shewanellaceae 1236|Gammaproteobacteria C PFAM iron-containing alcohol dehydrogenase - - - ko:K08325 ko00640,map00640 - R02528 RC00739 ko00000,ko00001,ko01000 - - - Fe-ADH k141_24642_16 1515746.HR45_16050 7.3e-114 333.0 COG1028@1|root,COG1028@2|Bacteria,1P9R4@1224|Proteobacteria,1RYF6@1236|Gammaproteobacteria,2QBCC@267890|Shewanellaceae 1236|Gammaproteobacteria IQ KR domain - - - - - - - - - - - - Polyketide_cyc2,adh_short k141_24642_17 634500.EbC_21550 3.68e-156 452.0 COG0477@1|root,COG2814@2|Bacteria,1MVD0@1224|Proteobacteria,1RS2J@1236|Gammaproteobacteria,3X76H@551|Erwinia 1236|Gammaproteobacteria EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 k141_24642_19 870967.VIS19158_06024 2.15e-70 216.0 COG0394@1|root,COG0394@2|Bacteria,1RH90@1224|Proteobacteria,1S5X6@1236|Gammaproteobacteria,1XXD3@135623|Vibrionales 135623|Vibrionales T Belongs to the low molecular weight phosphotyrosine protein phosphatase family - - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - LMWPc k141_24642_20 1116375.VEJY3_10740 2.61e-131 374.0 COG2109@1|root,COG2109@2|Bacteria,1MUN6@1224|Proteobacteria,1RMH9@1236|Gammaproteobacteria,1XSJ7@135623|Vibrionales 135623|Vibrionales H Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids btuR - 2.5.1.17 ko:K19221 ko00860,ko01100,map00860,map01100 M00122 R01492,R05220,R07268 RC00533 ko00000,ko00001,ko00002,ko01000 - - - Co_AT_N,CobA_CobO_BtuR k141_24642_21 1116375.VEJY3_10745 0.0 1104.0 COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,1RPFM@1236|Gammaproteobacteria,1XSC9@135623|Vibrionales 135623|Vibrionales M protein involved in outer membrane biogenesis asmA - - ko:K07289 - - - - ko00000 - - - AsmA k141_24642_22 223926.28807060 1.76e-144 408.0 COG0572@1|root,COG0572@2|Bacteria,1MWCH@1224|Proteobacteria,1RNZG@1236|Gammaproteobacteria,1XTHP@135623|Vibrionales 135623|Vibrionales F Cytidine monophosphokinase udk GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.48 ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PRK k141_24642_23 1219076.N646_1144 3.32e-242 667.0 COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,1RMJF@1236|Gammaproteobacteria,1XT74@135623|Vibrionales 135623|Vibrionales D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP mrp - - ko:K03593 - - - - ko00000,ko03029,ko03036 - - - ParA k141_979_1 489825.LYNGBM3L_13010 3.62e-86 263.0 COG0581@1|root,COG0581@2|Bacteria,1G2GA@1117|Cyanobacteria,1H9A2@1150|Oscillatoriales 1117|Cyanobacteria P PFAM Binding-protein-dependent transport system inner membrane component - - - ko:K02038 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 k141_35427_1 1385514.N782_09860 3.06e-66 209.0 COG1597@1|root,COG1597@2|Bacteria,1TQAU@1239|Firmicutes,4H9WD@91061|Bacilli,2Y967@289201|Pontibacillus 91061|Bacilli G to YegS from E. coli - - - - - - - - - - - - DAGK_cat k141_3162_1 1117647.M5M_16765 3.91e-108 325.0 COG2942@1|root,COG2942@2|Bacteria,1R7VZ@1224|Proteobacteria,1RY4Y@1236|Gammaproteobacteria 1236|Gammaproteobacteria G N-acylglucosamine 2-epimerase - - 5.3.1.8 ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 M00114 R01819 RC00376 ko00000,ko00001,ko00002,ko01000 - - - GlcNAc_2-epim k141_34163_1 218284.CCDN010000001_gene449 7.16e-134 408.0 COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,4HAFP@91061|Bacilli,1ZBJ3@1386|Bacillus 91061|Bacilli V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran k141_25971_1 218284.CCDN010000001_gene1139 3.55e-138 396.0 COG0414@1|root,COG0414@2|Bacteria,1TP7A@1239|Firmicutes,4HAIQ@91061|Bacilli,1ZAV5@1386|Bacillus 91061|Bacilli H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate panC GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 M00119 R02473 RC00096,RC00141 ko00000,ko00001,ko00002,ko01000 - - - Pantoate_ligase k141_9329_1 42565.FP66_06330 6.49e-97 301.0 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,1RQUR@1236|Gammaproteobacteria,1XIN6@135619|Oceanospirillales 135619|Oceanospirillales F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen - - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - LAGLIDADG_3,Ribonuc_red_lgC,Ribonuc_red_lgN k141_22322_1 218284.CCDN010000001_gene685 3.8e-157 462.0 COG0507@1|root,COG0507@2|Bacteria,1TPZH@1239|Firmicutes,4HATQ@91061|Bacilli,1ZAYS@1386|Bacillus 91061|Bacilli L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity recD2 - 3.1.11.5 ko:K03581 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_30,HHH_4,HHH_5,UvrD_C_2 k141_22322_2 218284.CCDN010000001_gene684 4.51e-18 81.6 COG0457@1|root,COG0457@2|Bacteria,1V1HX@1239|Firmicutes,4HG5V@91061|Bacilli,1ZCPW@1386|Bacillus 91061|Bacilli S COG0457 FOG TPR repeat yrrB - - - - - - - - - - - TPR_1,TPR_16,TPR_2,TPR_6,TPR_8 k141_14244_1 1517681.HW45_09840 1.29e-70 226.0 COG1172@1|root,COG1172@2|Bacteria,1MX7D@1224|Proteobacteria,1TCBB@1236|Gammaproteobacteria,1Y0JV@135623|Vibrionales 135623|Vibrionales G Sugar ABC transporter permease - - - ko:K10440 ko02010,map02010 M00212 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - BPD_transp_2 k141_16276_1 1116375.VEJY3_18246 4.33e-148 421.0 COG0583@1|root,COG0583@2|Bacteria,1PX1B@1224|Proteobacteria,1SYEI@1236|Gammaproteobacteria,1XYEZ@135623|Vibrionales 135623|Vibrionales K COG0583 Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_16276_2 1116375.VEJY3_18251 3.49e-223 615.0 COG0388@1|root,COG0388@2|Bacteria,1MWQG@1224|Proteobacteria,1RYY7@1236|Gammaproteobacteria,1XYN9@135623|Vibrionales 135623|Vibrionales S Carbon-nitrogen hydrolase - - 3.5.5.1 ko:K01501 ko00380,ko00460,ko00627,ko00643,ko00910,ko01120,map00380,map00460,map00627,map00643,map00910,map01120 - R00540,R01887,R03093,R03542,R05591,R07855 RC00315,RC00325,RC00617,RC00959,RC02811 ko00000,ko00001,ko01000 - - - CN_hydrolase k141_24644_1 218284.CCDN010000001_gene1446 6.71e-70 216.0 COG4721@1|root,COG4721@2|Bacteria,1UZIH@1239|Firmicutes,4HG48@91061|Bacilli,1ZPZB@1386|Bacillus 91061|Bacilli S ABC-type cobalt transport system, permease component ykoE - - ko:K16925 - M00582 - - ko00000,ko00002,ko02000 3.A.1.30 - - ABC_cobalt k141_17394_1 1294265.JCM21738_2272 2.99e-24 95.5 2DMXQ@1|root,32UHX@2|Bacteria,1VD2A@1239|Firmicutes,4HKUA@91061|Bacilli,1ZJEN@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_17394_2 1499685.CCFJ01000046_gene3102 3.56e-24 93.2 COG0526@1|root,COG0526@2|Bacteria,1VAS6@1239|Firmicutes,4HKGM@91061|Bacilli,1ZHAS@1386|Bacillus 91061|Bacilli CO Thioredoxin ytpP GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - - - - - - - - - - Thioredoxin k141_32858_1 42565.FP66_10295 3.32e-107 326.0 COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,1RMGA@1236|Gammaproteobacteria,1XHNC@135619|Oceanospirillales 135619|Oceanospirillales L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG - - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB_bind,DnaG_DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2 k141_34183_1 218284.CCDN010000005_gene3450 1.65e-51 168.0 2CIBU@1|root,30GF5@2|Bacteria,1V4EG@1239|Firmicutes,4HH80@91061|Bacilli,1ZGKU@1386|Bacillus 91061|Bacilli S Family of unknown function (DUF5366) yufK - - - - - - - - - - - DUF5366 k141_20942_1 383381.EH30_04525 3.86e-11 68.2 COG3121@1|root,COG3121@2|Bacteria,1RF0Y@1224|Proteobacteria,2U7QK@28211|Alphaproteobacteria,2K6EN@204457|Sphingomonadales 204457|Sphingomonadales NU Pili and flagellar-assembly chaperone, PapD N-terminal domain - - - - - - - - - - - - PapD_N k141_20942_4 1249627.D779_3180 7.49e-111 323.0 COG2071@1|root,COG2071@2|Bacteria,1NV5K@1224|Proteobacteria,1T05H@1236|Gammaproteobacteria,1WX3G@135613|Chromatiales 135613|Chromatiales S Peptidase C26 - - - ko:K07010 - - - - ko00000,ko01002 - - - Peptidase_C26 k141_20942_5 1129794.C427_2251 1.17e-133 390.0 28IBE@1|root,2Z8DX@2|Bacteria,1NC7D@1224|Proteobacteria,1RP6N@1236|Gammaproteobacteria,4641D@72275|Alteromonadaceae 1236|Gammaproteobacteria S Putative amidoligase enzyme - - - - - - - - - - - - Amidoligase_2 k141_20942_6 1535422.ND16A_2216 4.96e-264 736.0 COG1292@1|root,COG1292@2|Bacteria,1MV0K@1224|Proteobacteria,1RRSQ@1236|Gammaproteobacteria,2Q7HM@267889|Colwelliaceae 1236|Gammaproteobacteria U Belongs to the BCCT transporter (TC 2.A.15) family - - - - - - - - - - - - BCCT k141_3179_1 218284.CCDN010000001_gene559 1.04e-216 610.0 COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HA2G@91061|Bacilli,1ZAY1@1386|Bacillus 91061|Bacilli IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II lcfA - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding,AMP-binding_C k141_14256_1 218284.CCDN010000008_gene4249 1.48e-58 185.0 COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,4HAC9@91061|Bacilli,1ZCEB@1386|Bacillus 91061|Bacilli J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit rpsD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - ko:K02986 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S4,S4 k141_18982_1 240302.BN982_02416 1.22e-20 89.4 COG0253@1|root,COG0253@2|Bacteria,1TPMN@1239|Firmicutes,4HBH4@91061|Bacilli,3NE74@45667|Halobacillus 91061|Bacilli E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan dapF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 - - - DAP_epimerase k141_18982_2 218284.CCDN010000001_gene1271 6.38e-45 147.0 2A1JC@1|root,30PT9@2|Bacteria,1UB45@1239|Firmicutes,4IMGR@91061|Bacilli,1ZK4F@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_18982_3 218284.CCDN010000001_gene1270 1.35e-133 391.0 COG3434@1|root,COG3434@2|Bacteria,1TPWC@1239|Firmicutes,4HD4Q@91061|Bacilli,1ZDNG@1386|Bacillus 91061|Bacilli T signal transduction protein containing EAL and modified HD-GYP domains yuxH - - - - - - - - - - - EAL,HDOD k141_35445_1 218284.CCDN010000001_gene1911 4.06e-123 363.0 COG1419@1|root,COG1419@2|Bacteria,1TSP7@1239|Firmicutes,4H9VG@91061|Bacilli,1ZCJ9@1386|Bacillus 91061|Bacilli N Flagellar biosynthesis regulator FlhF flhF GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K02404 - - - - ko00000,ko02035 - - - SRP54 k141_12905_1 1294265.JCM21738_2122 1.07e-83 264.0 COG1368@1|root,COG1368@2|Bacteria,1TRMA@1239|Firmicutes,4H9S0@91061|Bacilli,1ZBBV@1386|Bacillus 91061|Bacilli M Belongs to the LTA synthase family yqgS - 2.7.8.20 ko:K01138,ko:K19005 ko00561,ko01100,map00561,map01100 - R05081,R10849 RC00017 ko00000,ko00001,ko01000 - - - Sulfatase k141_37568_1 1169144.KB910924_gene331 1.04e-75 231.0 28H7M@1|root,2Z7JU@2|Bacteria,1UG4F@1239|Firmicutes,4HHH8@91061|Bacilli,1ZHCY@1386|Bacillus 91061|Bacilli S phage tail protein - - - - - - - - - - - - - k141_37568_2 698758.AXY_02180 1.15e-33 119.0 2CK6F@1|root,32Z0X@2|Bacteria,1VIDI@1239|Firmicutes,4HPHE@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - k141_22356_1 218284.CCDN010000001_gene644 3.82e-113 334.0 COG0379@1|root,COG0379@2|Bacteria,1TP6R@1239|Firmicutes,4H9QG@91061|Bacilli,1ZAR3@1386|Bacillus 91061|Bacilli H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate nadA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 ko:K03517 ko00760,ko01100,map00760,map01100 M00115 R04292 RC01119 ko00000,ko00001,ko00002,ko01000 - - - NadA k141_30359_1 1294265.JCM21738_1721 4.68e-164 462.0 COG1366@1|root,COG1366@2|Bacteria,1V14Y@1239|Firmicutes,4HF64@91061|Bacilli,1ZDSZ@1386|Bacillus 91061|Bacilli T STAS domain - - - ko:K17763 - - - - ko00000,ko03021 - - - STAS k141_11725_1 218284.CCDN010000005_gene3242 2.18e-105 318.0 COG1233@1|root,COG1233@2|Bacteria,1TRN1@1239|Firmicutes,4HA5W@91061|Bacilli,1ZDED@1386|Bacillus 91061|Bacilli Q Flavin containing amine oxidoreductase - - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 ko:K10027 ko00906,ko01100,ko01110,map00906,map01100,map01110 - R04787,R04798,R04800,R09691,R09692 RC01214,RC02088,RC02605 ko00000,ko00001,ko01000 - - - Amino_oxidase k141_32889_1 42565.FP66_14810 6.48e-111 322.0 COG1191@1|root,COG1191@2|Bacteria,1MWEU@1224|Proteobacteria,1RMKJ@1236|Gammaproteobacteria,1XIKW@135619|Oceanospirillales 135619|Oceanospirillales K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes fliA - - ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 - - - ko00000,ko00001,ko02035,ko03021 - - - Sigma70_r2,Sigma70_r3,Sigma70_r4 k141_15062_1 1219084.AP014508_gene315 1.04e-33 121.0 COG0432@1|root,COG0432@2|Bacteria,2GD2P@200918|Thermotogae 200918|Thermotogae S PFAM Uncharacterised protein family UPF0047 - - - - - - - - - - - - UPF0047 k141_15062_2 1232452.BAIB02000002_gene38 1.64e-15 77.8 COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,247M2@186801|Clostridia 186801|Clostridia K Periplasmic binding protein LacI transcriptional regulator - - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_1,Peripla_BP_3 k141_19954_2 1453501.JELR01000002_gene329 1.42e-157 458.0 COG3063@1|root,COG3063@2|Bacteria,1R0M2@1224|Proteobacteria,1T4K4@1236|Gammaproteobacteria,46DCA@72275|Alteromonadaceae 1236|Gammaproteobacteria NU Tetratricopeptide repeat - - - - - - - - - - - - TPR_16,TPR_8,Transglut_core k141_6949_1 95619.PM1_0209780 4.15e-68 223.0 COG0388@1|root,COG0388@2|Bacteria,1P8FV@1224|Proteobacteria 1224|Proteobacteria S Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source - - - - - - - - - - - - CN_hydrolase k141_6949_2 656519.Halsa_1165 8e-27 108.0 COG1656@1|root,COG1656@2|Bacteria,1V62E@1239|Firmicutes,24IZW@186801|Clostridia 186801|Clostridia H Mut7-C RNAse domain - - - ko:K09122 - - - - ko00000 - - - Mut7-C,Ub-Mut7C k141_35446_1 218284.CCDN010000001_gene152 3.02e-162 464.0 COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,4HB3K@91061|Bacilli,1ZCJR@1386|Bacillus 91061|Bacilli C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes pdhD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyr_redox_2,Pyr_redox_dim k141_10446_1 218284.CCDN010000001_gene1790 1.61e-249 698.0 COG0021@1|root,COG0021@2|Bacteria,1TPIB@1239|Firmicutes,4HADA@91061|Bacilli,1ZBQ6@1386|Bacillus 91061|Bacilli G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate tkt - 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C,Transketolase_N k141_5732_2 218284.CCDN010000001_gene1752 1.76e-57 188.0 COG0626@1|root,COG0626@2|Bacteria,1TPC7@1239|Firmicutes,4HAFQ@91061|Bacilli,1ZAR9@1386|Bacillus 91061|Bacilli E cystathionine metB GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0016740,GO:0016765,GO:0016829,GO:0016846 2.5.1.48 ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017 R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946 RC00020,RC00056,RC00069,RC00420,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000 - - - Cys_Met_Meta_PP k141_4375_1 1173026.Glo7428_3056 2.54e-33 130.0 COG0612@1|root,COG0612@2|Bacteria,1G303@1117|Cyanobacteria 1117|Cyanobacteria S PFAM Peptidase M16 inactive domain ymxG - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C k141_20943_1 1123228.AUIH01000033_gene2686 6.73e-71 227.0 COG3328@1|root,COG3328@2|Bacteria,1MU4P@1224|Proteobacteria,1RNB3@1236|Gammaproteobacteria,1XMXK@135619|Oceanospirillales 135619|Oceanospirillales L MULE transposase domain - - - - - - - - - - - - Transposase_mut k141_24677_1 1230341.MJ3_08771 9.09e-26 102.0 COG0582@1|root,COG0582@2|Bacteria,1W1XZ@1239|Firmicutes 1239|Firmicutes L Pfam:Integrase_AP2 - - - - - - - - - - - - Arm-DNA-bind_4,Phage_int_SAM_3 k141_24677_3 1444310.JANV01000162_gene1225 2.53e-09 57.8 COG1396@1|root,COG1396@2|Bacteria 2|Bacteria K sequence-specific DNA binding - - - - - - - - - - - - HTH_3 k141_18984_1 218284.CCDN010000007_gene3954 2.64e-160 467.0 COG0247@1|root,COG2181@1|root,COG0247@2|Bacteria,COG2181@2|Bacteria,1TPG1@1239|Firmicutes,4HB2J@91061|Bacilli,1ZBAJ@1386|Bacillus 91061|Bacilli C COG0247 Fe-S oxidoreductase ywjF - - - - - - - - - - - CCG,Fer4_8 k141_15063_1 218284.CCDN010000008_gene4210 1.89e-120 352.0 COG3641@1|root,COG3641@2|Bacteria,1TS5F@1239|Firmicutes,4HC7U@91061|Bacilli,1ZCS4@1386|Bacillus 91061|Bacilli S Phosphotransferase system, EIIC - - - ko:K07035 - - - - ko00000 - - - PTS_EIIC_2 k141_9366_1 240302.BN982_02494 6.53e-86 261.0 COG1879@1|root,COG1879@2|Bacteria,1TQ1B@1239|Firmicutes,4HCSN@91061|Bacilli,3NDAU@45667|Halobacillus 91061|Bacilli G Periplasmic binding protein domain rbsB GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015749,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0034219,GO:0044425,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 - ko:K10439 ko02010,ko02030,map02010,map02030 M00212 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - Peripla_BP_4 k141_16297_1 218284.CCDN010000003_gene2974 6.97e-95 288.0 COG3583@1|root,COG3584@1|root,COG3583@2|Bacteria,COG3584@2|Bacteria,1TTIK@1239|Firmicutes,4HC79@91061|Bacilli,1ZC0Q@1386|Bacillus 91061|Bacilli T protein conserved in bacteria yabE - - - - - - - - - - - 3D,DUF348,G5 k141_16297_2 218284.CCDN010000003_gene2975 6.84e-70 214.0 COG1658@1|root,COG1658@2|Bacteria,1V3K3@1239|Firmicutes,4HH5Y@91061|Bacilli,1ZFNN@1386|Bacillus 91061|Bacilli J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step rnmV GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043822,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 3.1.26.8 ko:K05985 - - - - ko00000,ko01000 - - - DUF4093,Toprim,Toprim_4 k141_3181_1 260799.BAS0455 7.79e-49 166.0 COG4722@1|root,COG4722@2|Bacteria,1VZIH@1239|Firmicutes,4I8NR@91061|Bacilli,1ZJI2@1386|Bacillus 91061|Bacilli S Phage tail protein - - - - - - - - - - - - Sipho_tail k141_11727_2 1453501.JELR01000002_gene130 3.9e-21 92.0 COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,1RMNZ@1236|Gammaproteobacteria,4641P@72275|Alteromonadaceae 1236|Gammaproteobacteria I Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA acsA GO:0003674,GO:0003824,GO:0003987,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006083,GO:0006084,GO:0006085,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006473,GO:0006476,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016054,GO:0016405,GO:0016787,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017001,GO:0017144,GO:0018130,GO:0018193,GO:0018205,GO:0018394,GO:0019213,GO:0019427,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033558,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034421,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0035601,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0043687,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0045733,GO:0046390,GO:0046395,GO:0046483,GO:0050218,GO:0051186,GO:0051188,GO:0055086,GO:0071616,GO:0071704,GO:0072329,GO:0072521,GO:0072522,GO:0090407,GO:0098732,GO:0140096,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 - - iE2348C_1286.E2348C_4392,iYL1228.KPN_04478 ACAS_N,AMP-binding,AMP-binding_C k141_23702_2 1453501.JELR01000002_gene186 8.09e-148 427.0 COG0730@1|root,COG0730@2|Bacteria,1QRFH@1224|Proteobacteria,1RRFY@1236|Gammaproteobacteria,465YS@72275|Alteromonadaceae 1236|Gammaproteobacteria S Sulfite exporter TauE/SafE - - - - - - - - - - - - TauE k141_23702_3 1123054.KB907705_gene2488 3.42e-18 85.9 COG0665@1|root,COG0665@2|Bacteria,1MU40@1224|Proteobacteria,1RMJY@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Tryptophan halogenase prnA - 1.14.19.9 ko:K14266 ko00404,ko01130,map00404,map01130 M00789,M00790 R09570 RC00949 ko00000,ko00001,ko00002,ko01000 - - - Trp_halogenase k141_24678_1 1219076.N646_2436 5.96e-135 388.0 COG1494@1|root,COG1494@2|Bacteria,1MUB1@1224|Proteobacteria,1RR0E@1236|Gammaproteobacteria,1XTI1@135623|Vibrionales 135623|Vibrionales G COG1494 Fructose-1,6-bisphosphatase sedoheptulose 1,7-bisphosphatase and related proteins glpX - 3.1.3.11 ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 M00003,M00165,M00167 R00762,R04780 RC00017 ko00000,ko00001,ko00002,ko01000 - - - FBPase_glpX k141_19955_1 218284.CCDN010000002_gene2076 4.41e-242 671.0 COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,4HAAI@91061|Bacilli,1ZBC5@1386|Bacillus 91061|Bacilli S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family yhdH - - ko:K03308 - - - - ko00000 2.A.22.4,2.A.22.5 - - SNF k141_14258_1 218284.CCDN010000001_gene600 4.55e-112 334.0 COG0373@1|root,COG0373@2|Bacteria,1TQN9@1239|Firmicutes,4HAVC@91061|Bacilli,1ZBER@1386|Bacillus 91061|Bacilli H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) hemA - 1.2.1.70 ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R04109 RC00055,RC00149 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS08420 GlutR_N,GlutR_dimer,Shikimate_DH k141_37839_4 1453501.JELR01000002_gene122 1.37e-59 187.0 COG1186@1|root,COG1186@2|Bacteria,1RH75@1224|Proteobacteria,1S5YQ@1236|Gammaproteobacteria,4678H@72275|Alteromonadaceae 1236|Gammaproteobacteria J COG1186 Protein chain release factor B yaeJ GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 - ko:K15034 - - - - ko00000,ko03012 - - - RF-1 k141_17718_1 1279017.AQYJ01000026_gene215 1.34e-149 435.0 COG0438@1|root,COG0438@2|Bacteria,1N9EV@1224|Proteobacteria,1RYRV@1236|Gammaproteobacteria,46CMH@72275|Alteromonadaceae 1236|Gammaproteobacteria M Glycosyl transferases group 1 gt4G - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 k141_28259_1 1453501.JELR01000001_gene2858 4.13e-91 277.0 COG1307@1|root,COG1307@2|Bacteria,1R5M9@1224|Proteobacteria,1RZYN@1236|Gammaproteobacteria,46813@72275|Alteromonadaceae 1236|Gammaproteobacteria S Uncharacterised protein, DegV family COG1307 - - - - - - - - - - - - DegV k141_34424_1 1131730.BAVI_00305 5.61e-19 83.6 2DZE5@1|root,32V8E@2|Bacteria,1VHNT@1239|Firmicutes,4IRQ8@91061|Bacilli,1ZRWP@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_34424_2 1121936.AUHI01000006_gene2075 1.6e-56 181.0 COG2306@1|root,COG2306@2|Bacteria,1VARK@1239|Firmicutes,4HHJ8@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF402) - - - ko:K09145 - - - - ko00000 - - - DUF402 k141_17719_1 1211814.CAPG01000077_gene3666 8.07e-07 52.8 COG3860@1|root,COG3860@2|Bacteria,1VA52@1239|Firmicutes,4HN02@91061|Bacilli,1ZIRW@1386|Bacillus 91061|Bacilli S GIY-YIG catalytic domain - - - - - - - - - - - - GIY-YIG k141_37840_1 1294265.JCM21738_3398 3.73e-149 430.0 COG0168@1|root,COG0168@2|Bacteria,1TQ4S@1239|Firmicutes,4H9ME@91061|Bacilli,1ZD2H@1386|Bacillus 91061|Bacilli P COG0168 Trk-type K transport systems, membrane components ktrD - - - - - - - - - - - TrkH k141_31696_1 525909.Afer_0568 3.31e-06 49.7 COG0822@1|root,COG0822@2|Bacteria,2IHY9@201174|Actinobacteria,4CN20@84992|Acidimicrobiia 84992|Acidimicrobiia C NifU-like N terminal domain - - - ko:K04488 - - - - ko00000 - - - NifU_N k141_31696_2 861299.J421_6151 4.1e-22 96.7 COG1032@1|root,COG1032@2|Bacteria 2|Bacteria C radical SAM domain protein MA20_16100 - - - - - - - - - - - B12-binding,DUF4070,Radical_SAM k141_3429_1 1280001.BAOA01000051_gene1592 4.31e-112 347.0 COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,1T1X2@1236|Gammaproteobacteria,1XUBS@135623|Vibrionales 135623|Vibrionales Q COG2931, RTX toxins and related Ca2 -binding proteins - - - - - - - - - - - - - k141_17720_1 218284.CCDN010000002_gene2101 2.38e-106 314.0 COG2984@1|root,COG2984@2|Bacteria,1TPB0@1239|Firmicutes,4HESK@91061|Bacilli,1ZBBC@1386|Bacillus 91061|Bacilli S transport system, periplasmic component - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind k141_8068_1 649747.HMPREF0083_05453 1.84e-79 247.0 COG1712@1|root,COG1712@2|Bacteria,1UZUW@1239|Firmicutes,4HE27@91061|Bacilli,26WPE@186822|Paenibacillaceae 91061|Bacilli S Domain of unknown function DUF108 - - 1.4.1.21 ko:K06989 ko00760,ko01100,map00760,map01100 - R07407,R07410 RC02566 ko00000,ko00001,ko01000 - - - DUF108,NAD_binding_3 k141_8068_2 1196031.ALEG01000054_gene5533 7.77e-21 84.7 COG0633@1|root,COG0633@2|Bacteria,1U9MB@1239|Firmicutes,4IJSS@91061|Bacilli,1ZGIU@1386|Bacillus 91061|Bacilli C 2Fe-2S iron-sulfur cluster binding domain - - - - - - - - - - - - Fer2 k141_16558_1 218284.CCDN010000007_gene3791 9.65e-252 693.0 COG0592@1|root,COG0592@2|Bacteria,1TQ7J@1239|Firmicutes,4H9TF@91061|Bacilli,1ZAVV@1386|Bacillus 91061|Bacilli L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria dnaN - 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_beta,DNA_pol3_beta_3 k141_28261_1 1385515.N791_08055 1.58e-126 372.0 COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,1RMNB@1236|Gammaproteobacteria,1X43Q@135614|Xanthomonadales 135614|Xanthomonadales I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism accC - 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 k141_28261_2 522373.Smlt4240 5.49e-18 78.6 COG0511@1|root,COG0511@2|Bacteria,1RCXA@1224|Proteobacteria,1S3YP@1236|Gammaproteobacteria,1X67R@135614|Xanthomonadales 135614|Xanthomonadales I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA accB - - ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742 RC00040,RC00367 ko00000,ko00001,ko00002 - - - Biotin_lipoyl k141_30541_1 1279017.AQYJ01000026_gene80 1.22e-20 86.7 COG4929@1|root,COG4929@2|Bacteria,1NURJ@1224|Proteobacteria,1SBG7@1236|Gammaproteobacteria,46BI1@72275|Alteromonadaceae 1236|Gammaproteobacteria S GDYXXLXY protein - - - - - - - - - - - - GDYXXLXY k141_30541_2 1279017.AQYJ01000026_gene81 4.24e-193 550.0 COG4872@1|root,COG4872@2|Bacteria,1NAIX@1224|Proteobacteria,1S1XV@1236|Gammaproteobacteria,46ADY@72275|Alteromonadaceae 1236|Gammaproteobacteria S Predicted membrane protein (DUF2157) - - - - - - - - - - - - DUF2157 k141_17721_1 1521187.JPIM01000006_gene1768 1.42e-67 218.0 COG0766@1|root,COG0766@2|Bacteria,2G666@200795|Chloroflexi,374XF@32061|Chloroflexia 32061|Chloroflexia M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine murA - 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R00660 RC00350 ko00000,ko00001,ko01000,ko01011 - - - EPSP_synthase k141_37842_1 1294265.JCM21738_630 2.34e-98 289.0 COG0424@1|root,COG0424@2|Bacteria,1V6FH@1239|Firmicutes,4HIMK@91061|Bacilli,1ZGDP@1386|Bacillus 91061|Bacilli D septum formation protein Maf maf GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0005575,GO:0005623,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0022402,GO:0022607,GO:0030428,GO:0032506,GO:0044085,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0090529,GO:1902410,GO:1903047 - ko:K06287 - - - - ko00000 - - - Maf k141_21215_1 1120953.AUBH01000002_gene1580 8.17e-30 114.0 COG1028@1|root,COG1028@2|Bacteria,1MXNQ@1224|Proteobacteria,1RRVQ@1236|Gammaproteobacteria,464RH@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ KR domain - - - - - - - - - - - - adh_short k141_21215_2 318167.Sfri_2065 3.4e-58 185.0 COG2030@1|root,COG2030@2|Bacteria,1RHPH@1224|Proteobacteria,1S0DD@1236|Gammaproteobacteria,2QCYF@267890|Shewanellaceae 1236|Gammaproteobacteria I PFAM MaoC domain protein dehydratase nodN - - - - - - - - - - - MaoC_dehydratas k141_21215_3 1279017.AQYJ01000018_gene819 5.26e-130 375.0 COG1028@1|root,COG1028@2|Bacteria,1R413@1224|Proteobacteria,1RSKB@1236|Gammaproteobacteria,4667I@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ Short-chain dehydrogenase reductase sDR - - - - - - - - - - - - adh_short_C2 k141_3430_1 565034.BHWA1_00153 1.48e-49 182.0 COG0525@1|root,COG0525@2|Bacteria,2J659@203691|Spirochaetes 203691|Spirochaetes J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner valS - 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 k141_34426_1 218284.CCDN010000002_gene2037 1.01e-125 367.0 COG0477@1|root,COG2814@2|Bacteria,1TQHD@1239|Firmicutes,4HBCZ@91061|Bacilli,1ZDDG@1386|Bacillus 91061|Bacilli EGP COG0477 Permeases of the major facilitator superfamily - - - - - - - - - - - - MFS_1,Sugar_tr k141_16559_1 1122179.KB890491_gene4425 4.55e-104 315.0 COG1004@1|root,COG1004@2|Bacteria,4NE00@976|Bacteroidetes,1IQ5C@117747|Sphingobacteriia 976|Bacteroidetes M Belongs to the UDP-glucose GDP-mannose dehydrogenase family tuaD - 1.1.1.22 ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 M00014,M00129,M00361,M00362 R00286 RC00291 ko00000,ko00001,ko00002,ko01000 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N k141_30542_1 1121104.AQXH01000003_gene363 1.12e-50 171.0 COG3264@1|root,COG3264@2|Bacteria,4NFMR@976|Bacteroidetes,1IX0A@117747|Sphingobacteriia 976|Bacteroidetes M Conserved TM helix mscS - - ko:K03442 - - - - ko00000,ko02000 1.A.23.2 - - MS_channel,TM_helix k141_29715_1 1453501.JELR01000002_gene379 2.69e-88 280.0 COG3291@1|root,COG3291@2|Bacteria 2|Bacteria S metallopeptidase activity - - 3.2.1.78 ko:K01218 ko00051,ko02024,map00051,map02024 - R01332 RC00467 ko00000,ko00001,ko01000 - GH26 - Alginate_lyase2,F5_F8_type_C,Laminin_G_3,PKD k141_15262_1 1294265.JCM21738_2769 1.5e-137 400.0 COG3611@1|root,COG3611@2|Bacteria,1TSBB@1239|Firmicutes,4H9RI@91061|Bacilli,1ZBJY@1386|Bacillus 91061|Bacilli L Membrane attachment protein dnaB - - ko:K03346 - - - - ko00000,ko03032 - - - DnaB_2 k141_15262_2 1294265.JCM21738_2770 1.4e-44 152.0 COG1484@1|root,COG1484@2|Bacteria,1TPZX@1239|Firmicutes,4HABS@91061|Bacilli,1ZB6G@1386|Bacillus 91061|Bacilli L Primosomal protein DnaI dnaI GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - ko:K11144 - - - - ko00000,ko03032 - - - DnaI_N,IstB_IS21 k141_36543_1 1453501.JELR01000002_gene410 1.53e-70 219.0 COG2197@1|root,COG2197@2|Bacteria,1NI3Z@1224|Proteobacteria,1SJ39@1236|Gammaproteobacteria 1236|Gammaproteobacteria KT helix_turn_helix, Lux Regulon - - - ko:K04333 ko02026,map02026 - - - ko00000,ko00001,ko03000 - - - GerE k141_36543_2 1453501.JELR01000002_gene411 1.18e-57 183.0 2C2E6@1|root,2ZPXX@2|Bacteria,1N6U8@1224|Proteobacteria,1SEU1@1236|Gammaproteobacteria 1236|Gammaproteobacteria S assembly protein CsgE csgE - - ko:K04337 - - - - ko00000,ko02044 - - - CsgE k141_36543_3 1279017.AQYJ01000028_gene2520 3.63e-60 189.0 2DEP1@1|root,32U3R@2|Bacteria,1N4PQ@1224|Proteobacteria,1S83R@1236|Gammaproteobacteria,4696P@72275|Alteromonadaceae 1236|Gammaproteobacteria S Type VIII secretion system (T8SS), CsgF protein - - - ko:K04338 - - - - ko00000,ko02044 - - - CsgF k141_36543_4 1042377.AFPJ01000051_gene42 1.98e-147 421.0 COG1462@1|root,COG1462@2|Bacteria,1MVZM@1224|Proteobacteria,1RQ5F@1236|Gammaproteobacteria,466QU@72275|Alteromonadaceae 1236|Gammaproteobacteria M Curli production assembly/transport component CsgG csgG GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0019867,GO:0022610,GO:0030288,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0033036,GO:0042597,GO:0042710,GO:0042802,GO:0042886,GO:0044010,GO:0044425,GO:0044462,GO:0044464,GO:0044764,GO:0045184,GO:0051179,GO:0051234,GO:0051704,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098552 - ko:K06214 - - - - ko00000,ko02044 - - - CsgG k141_17722_2 926690.KE386573_gene1749 1.03e-17 83.6 COG3332@1|root,arCOG06429@2157|Archaea,2XU65@28890|Euryarchaeota,23UCP@183963|Halobacteria 183963|Halobacteria S Transport and Golgi organisation 2 - - - - - - - - - - - - TANGO2 k141_37843_1 1453501.JELR01000002_gene336 4.28e-78 260.0 COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,1RM9X@1236|Gammaproteobacteria,46433@72275|Alteromonadaceae 1236|Gammaproteobacteria J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019538,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034645,GO:0036094,GO:0043021,GO:0043024,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:0097216,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N,IF2_assoc k141_2216_1 1121324.CLIT_2c01920 8.91e-163 482.0 COG0446@1|root,COG0607@1|root,COG2210@1|root,COG0446@2|Bacteria,COG0607@2|Bacteria,COG2210@2|Bacteria,1TPWW@1239|Firmicutes,2484C@186801|Clostridia,25QTC@186804|Peptostreptococcaceae 186801|Clostridia P Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain cdr - - - - - - - - - - - DrsE_2,Pyr_redox_2,Pyr_redox_dim,Rhodanese,TusA k141_3431_1 1196031.ALEG01000072_gene953 5.37e-97 287.0 COG1028@1|root,COG1028@2|Bacteria,1TRVE@1239|Firmicutes,4HCFY@91061|Bacilli,1ZAXT@1386|Bacillus 91061|Bacilli IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) fabL GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.3.1.104 ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00083 R01404,R04430,R04725,R04956,R04959,R04962,R04967,R04970 RC00052,RC00076,RC00120 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 k141_28262_1 218284.CCDN010000001_gene94 1.3e-131 389.0 COG4365@1|root,COG4365@2|Bacteria,1TQ2P@1239|Firmicutes,4HA2Z@91061|Bacilli,1ZBMV@1386|Bacillus 91061|Bacilli S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH bshC - - ko:K22136 - - - - ko00000 - - - BshC k141_34427_1 406124.ACPC01000018_gene2668 5.13e-22 87.0 29T44@1|root,30EAT@2|Bacteria,1UCBR@1239|Firmicutes,4INU6@91061|Bacilli,1ZNYE@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_17723_1 1036674.A28LD_2192 2.55e-23 100.0 COG1473@1|root,COG1473@2|Bacteria,1MUIV@1224|Proteobacteria,1RQAM@1236|Gammaproteobacteria,2QFRZ@267893|Idiomarinaceae 1236|Gammaproteobacteria M Peptidase dimerisation domain amaA - - ko:K01436 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 k141_33152_1 1294265.JCM21738_1716 2.86e-123 356.0 COG1284@1|root,COG1284@2|Bacteria,1TQTP@1239|Firmicutes,4HBV2@91061|Bacilli,1ZCF3@1386|Bacillus 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2179) - - - - - - - - - - - - DUF2179,YitT_membrane k141_16560_1 1517416.IDAT_10725 1.66e-13 72.8 COG0457@1|root,COG0457@2|Bacteria,1QWBQ@1224|Proteobacteria,1T2T1@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Bacteriophage N adsorption protein A C-term - - - ko:K11739 - - - - ko00000 - - - NfrA_C,TPR_15 k141_16560_2 675814.VIC_001635 1.48e-66 224.0 COG1215@1|root,COG1215@2|Bacteria,1P7GR@1224|Proteobacteria,1RNP2@1236|Gammaproteobacteria,1XURS@135623|Vibrionales 135623|Vibrionales M Glycosyltransferase like family 2 - - - ko:K11740 - - - - ko00000 - - - Glyco_trans_2_3,T2SSE_N k141_28263_1 649639.Bcell_2135 3.45e-28 103.0 COG3526@1|root,COG3526@2|Bacteria,1VKFI@1239|Firmicutes,4HR9S@91061|Bacilli,1ZKKR@1386|Bacillus 91061|Bacilli O Rdx family - - - ko:K07401 - - - - ko00000 - - - Rdx k141_3432_1 1198232.CYCME_1424 4.59e-22 96.3 COG4424@1|root,COG4424@2|Bacteria,1N77D@1224|Proteobacteria,1RZKD@1236|Gammaproteobacteria,4621C@72273|Thiotrichales 72273|Thiotrichales S Sulfotransferase family - - - - - - - - - - - - Sulfotransfer_1 k141_31698_1 218284.CCDN010000001_gene1409 2.94e-231 645.0 COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HANF@91061|Bacilli,1ZS27@1386|Bacillus 91061|Bacilli T Histidine kinase - - - - - - - - - - - - HAMP,HATPase_c,HisKA k141_2218_1 1122217.KB899610_gene19 1.79e-09 62.8 COG3152@1|root,COG3152@2|Bacteria,1UVVX@1239|Firmicutes,4H601@909932|Negativicutes 909932|Negativicutes S zinc-ribbon domain - - - - - - - - - - - - DUF805,zinc_ribbon_2 k141_30545_1 1294265.JCM21738_4199 6.47e-89 262.0 29RCN@1|root,30CET@2|Bacteria,1U9RQ@1239|Firmicutes,4IJY2@91061|Bacilli,1ZEJJ@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_16562_1 1042377.AFPJ01000028_gene2296 1.11e-109 327.0 COG0477@1|root,COG2814@2|Bacteria,1MV79@1224|Proteobacteria,1RQ2B@1236|Gammaproteobacteria,469XP@72275|Alteromonadaceae 1236|Gammaproteobacteria EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 k141_34429_2 1462526.BN990_02936 1.38e-69 225.0 COG1231@1|root,COG1231@2|Bacteria,1TRJC@1239|Firmicutes,4HBN4@91061|Bacilli 91061|Bacilli E Monoamine oxidase - - 1.4.3.4 ko:K00274 ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034 M00135 R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354 RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713 ko00000,ko00001,ko00002,ko01000 - - - Amino_oxidase k141_10653_1 1279017.AQYJ01000026_gene58 1.26e-305 932.0 COG1361@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4932@2|Bacteria,1R5G4@1224|Proteobacteria,1SEWA@1236|Gammaproteobacteria,469S7@72275|Alteromonadaceae 1236|Gammaproteobacteria M Domain of unknown function DUF11 - - - - - - - - - - - - DUF11,SdrD_B k141_10653_2 1279017.AQYJ01000026_gene57 0.0 2506.0 COG1360@1|root,COG2885@1|root,COG1360@2|Bacteria,COG2885@2|Bacteria,1QW22@1224|Proteobacteria,1T4AK@1236|Gammaproteobacteria,46ACU@72275|Alteromonadaceae 1236|Gammaproteobacteria M OmpA family - - - - - - - - - - - - DUF11,OmpA k141_16584_5 1236542.BALM01000005_gene2581 4.29e-231 645.0 2BAW9@1|root,324BV@2|Bacteria,1MYEZ@1224|Proteobacteria,1S7RU@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_16584_6 754436.JCM19237_5384 3.6e-193 551.0 2EM8N@1|root,31P77@2|Bacteria,1NPG1@1224|Proteobacteria,1SH3B@1236|Gammaproteobacteria,1Y0DJ@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_16584_7 1236542.BALM01000005_gene2583 7.59e-240 664.0 28JEY@1|root,2Z990@2|Bacteria,1QHPG@1224|Proteobacteria,1RQCT@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_16584_8 754436.JCM19237_5382 2.13e-102 303.0 2EJ5E@1|root,31P8A@2|Bacteria,1QKY5@1224|Proteobacteria,1TJ49@1236|Gammaproteobacteria,1Y0HJ@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_16584_10 1116375.VEJY3_23076 6.8e-86 254.0 COG1607@1|root,COG1607@2|Bacteria,1RAEQ@1224|Proteobacteria,1S313@1236|Gammaproteobacteria,1XTW2@135623|Vibrionales 135623|Vibrionales I Acyl-CoA hydrolase - - - - - - - - - - - - 4HBT k141_37891_1 1196031.ALEG01000005_gene5585 8.85e-72 220.0 COG1670@1|root,COG1670@2|Bacteria,1V1N3@1239|Firmicutes,4HFUW@91061|Bacilli,1ZRB6@1386|Bacillus 91061|Bacilli J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins - - - - - - - - - - - - Acetyltransf_3 k141_37891_2 1034347.CAHJ01000058_gene735 4.42e-14 65.9 2DKJQ@1|root,309R4@2|Bacteria,1U5IV@1239|Firmicutes,4IF9M@91061|Bacilli,1ZK2V@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2639) - - - - - - - - - - - - DUF2639 k141_17775_1 218284.CCDN010000001_gene44 7.96e-05 43.9 COG0223@1|root,COG0223@2|Bacteria,1TQ32@1239|Firmicutes,4HART@91061|Bacilli,1ZBSP@1386|Bacillus 91061|Bacilli J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus fmt GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 ko:K00604 ko00670,ko00970,map00670,map00970 - R03940 RC00026,RC00165 ko00000,ko00001,ko01000 - - iSB619.SA_RS06010 Formyl_trans_C,Formyl_trans_N k141_17775_2 218284.CCDN010000001_gene43 1.96e-123 363.0 COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1TP3N@1239|Firmicutes,4HBQ6@91061|Bacilli,1ZCWU@1386|Bacillus 91061|Bacilli J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA sun GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 ko:K03500 - - - - ko00000,ko01000,ko03009 - - - Methyltr_RsmB-F,Methyltr_RsmF_N,NusB k141_28312_1 768066.HELO_1131 2.61e-99 305.0 COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,1RPQD@1236|Gammaproteobacteria,1XJ06@135619|Oceanospirillales 135619|Oceanospirillales E C-terminal region of peptidase_M24 - - 3.4.11.9 ko:K01262 - - - - ko00000,ko01000,ko01002 - - - Creatinase_N,Creatinase_N_2,Peptidase_M24,Peptidase_M24_C k141_8098_1 218284.CCDN010000006_gene3588 6.61e-71 224.0 COG1396@1|root,COG1396@2|Bacteria 2|Bacteria K sequence-specific DNA binding - - - ko:K18830 - - - - ko00000,ko02048,ko03000 - - - HTH_19,HTH_3 k141_3483_1 1453501.JELR01000005_gene1577 3.88e-97 311.0 COG1629@1|root,COG1629@2|Bacteria,1MV8W@1224|Proteobacteria,1RQEQ@1236|Gammaproteobacteria,46A77@72275|Alteromonadaceae 1236|Gammaproteobacteria P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec k141_33195_1 265729.GS18_0205705 9.75e-90 268.0 COG0745@1|root,COG0745@2|Bacteria,1TSWT@1239|Firmicutes,4HBSC@91061|Bacilli,1ZCSV@1386|Bacillus 91061|Bacilli T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain hssR - - ko:K02483 - - - - ko00000,ko02022 - - - Response_reg,Trans_reg_C k141_33195_2 218284.CCDN010000006_gene3547 1.92e-71 217.0 COG1764@1|root,COG1764@2|Bacteria,1V7KG@1239|Firmicutes,4HJ7U@91061|Bacilli,1ZQRA@1386|Bacillus 91061|Bacilli O OsmC-like protein ohrA1 - - - - - - - - - - - OsmC k141_28313_2 1280001.BAOA01000064_gene2623 9.62e-27 101.0 COG0250@1|root,COG0250@2|Bacteria,1N01W@1224|Proteobacteria,1S91B@1236|Gammaproteobacteria,1XX33@135623|Vibrionales 135623|Vibrionales K Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components rfaH - - ko:K05785 - - - - ko00000,ko03000 - - - NusG k141_4664_1 279010.BL03335 4.01e-109 329.0 COG3333@1|root,COG3333@2|Bacteria,1TPE7@1239|Firmicutes,4HADN@91061|Bacilli,1ZBVK@1386|Bacillus 91061|Bacilli S Tripartite tricarboxylate transporter TctA family - - - ko:K07793 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.80.1 - - TctA k141_3484_2 218284.CCDN010000002_gene2008 5.13e-87 265.0 COG0505@1|root,COG0505@2|Bacteria,1TQ8N@1239|Firmicutes,4HAYC@91061|Bacilli,1ZBBD@1386|Bacillus 91061|Bacilli F Carbamoyl-phosphate synthetase glutamine chain carA GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_sm_chain,GATase k141_2262_1 218284.CCDN010000004_gene3059 2.17e-119 350.0 COG0772@1|root,COG0772@2|Bacteria,1TPGH@1239|Firmicutes,4HAV4@91061|Bacilli,1ZBSB@1386|Bacillus 91061|Bacilli D Belongs to the SEDS family rodA - - ko:K05837 - - - - ko00000,ko03036 - - - FTSW_RODA_SPOVE k141_4665_1 1248916.ANFY01000003_gene742 2.76e-23 96.3 COG3751@1|root,COG3751@2|Bacteria,1MYBU@1224|Proteobacteria,2UAT5@28211|Alphaproteobacteria,2K2VM@204457|Sphingomonadales 204457|Sphingomonadales O 2OG-Fe(II) oxygenase superfamily - - - - - - - - - - - - 2OG-FeII_Oxy_4 k141_4665_2 1384056.N787_04805 1.67e-36 139.0 COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,1RNVA@1236|Gammaproteobacteria,1X6C3@135614|Xanthomonadales 135614|Xanthomonadales S Putative 2OG-Fe(II) oxygenase - - - - - - - - - - - - 2OG-FeII_Oxy_5,TPR_16,TPR_19 k141_31742_1 223926.28806524 1.48e-183 512.0 COG0037@1|root,COG0037@2|Bacteria,1MW5Q@1224|Proteobacteria,1RN2H@1236|Gammaproteobacteria,1XTQ4@135623|Vibrionales 135623|Vibrionales J Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system ttcA - - ko:K14058 - - - - ko00000,ko03016 - - - ATP_bind_3 k141_31742_2 223926.28806526 1.27e-222 614.0 COG0589@1|root,COG0589@2|Bacteria,1MVZS@1224|Proteobacteria,1RPAE@1236|Gammaproteobacteria,1XSRX@135623|Vibrionales 135623|Vibrionales T COG0589 Universal stress protein UspA and related nucleotide-binding proteins uspE - - ko:K14055 - - - - ko00000 - - - Usp k141_31742_3 223926.28806527 1.68e-173 484.0 COG0664@1|root,COG0664@2|Bacteria,1MVGE@1224|Proteobacteria,1RPTB@1236|Gammaproteobacteria,1XT6M@135623|Vibrionales 135623|Vibrionales K COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases fnr - - ko:K01420 - - - - ko00000,ko03000 - - - HTH_Crp_2,cNMP_binding k141_31742_4 1116375.VEJY3_07335 3.95e-131 375.0 COG2836@1|root,COG2836@2|Bacteria,1RIGJ@1224|Proteobacteria,1S5V1@1236|Gammaproteobacteria,1XTG2@135623|Vibrionales 135623|Vibrionales S Cytochrome C biogenesis protein transmembrane region braZ - - ko:K09792 - - - - ko00000 - - - DsbD_2 k141_31742_5 945550.VISI1226_20839 1.74e-22 87.4 COG3197@1|root,COG3197@2|Bacteria,1NG90@1224|Proteobacteria,1SGQG@1236|Gammaproteobacteria,1XZ01@135623|Vibrionales 135623|Vibrionales P protein, possibly involved in nitrogen fixation ccoS - - - - - - - - - - - FixS k141_31742_6 223926.28806530 0.0 1207.0 COG2217@1|root,COG2608@1|root,COG2217@2|Bacteria,COG2608@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,1XSV0@135623|Vibrionales 135623|Vibrionales P cation transport ATPase ccoI - 3.6.3.4 ko:K01533 - - R00086 RC00002 ko00000,ko01000 3.A.3.5 - - ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase k141_28315_1 1191523.MROS_1555 3.39e-49 175.0 COG1132@1|root,COG1132@2|Bacteria 2|Bacteria V (ABC) transporter MdlB - - ko:K06147,ko:K18890 ko02010,map02010 M00707 - - ko00000,ko00001,ko00002,ko02000 3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran k141_4666_1 1279017.AQYJ01000024_gene1101 8.03e-103 313.0 COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,464KS@72275|Alteromonadaceae 1236|Gammaproteobacteria NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB pilB - - ko:K02652 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE,T2SSE_N k141_2264_1 1453501.JELR01000002_gene893 5.35e-90 265.0 COG3157@1|root,COG3157@2|Bacteria,1R9GB@1224|Proteobacteria,1RYJ5@1236|Gammaproteobacteria,4689B@72275|Alteromonadaceae 1236|Gammaproteobacteria S Type VI secretion system effector, Hcp - - - ko:K11903 ko02025,ko03070,map02025,map03070 M00334 - - ko00000,ko00001,ko00002,ko02044 - - - T6SS_HCP k141_9573_3 1279017.AQYJ01000027_gene1962 2.63e-62 207.0 COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,1RMGJ@1236|Gammaproteobacteria,46A3P@72275|Alteromonadaceae 1236|Gammaproteobacteria Q COG1233 Phytoene dehydrogenase and related proteins - - 1.3.99.23 ko:K09516 ko00830,map00830 - R07163 RC01835 ko00000,ko00001,ko01000 - - - Amino_oxidase,FAD_binding_6,NAD_binding_1,NAD_binding_8 k141_28614_1 1476583.DEIPH_ctg011orf0111 3.55e-14 75.5 COG0402@1|root,COG0402@2|Bacteria,1WJJP@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus F COG0402 Cytosine deaminase and related metal-dependent - GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006144,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008892,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0046098,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0072521,GO:1901360,GO:1901564 3.5.4.3 ko:K01487 ko00230,ko01100,map00230,map01100 - R01676 RC00204 ko00000,ko00001,ko01000 - - - Amidohydro_1 k141_30990_2 218284.CCDN010000002_gene2745 1.7e-56 182.0 28PJY@1|root,2ZC9F@2|Bacteria,1V390@1239|Firmicutes,4HG7F@91061|Bacilli,1ZDN7@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF1836) ykrK - - - - - - - - - - - DUF1836 k141_21485_1 866895.HBHAL_5029 2.97e-63 203.0 COG1633@1|root,COG4902@1|root,COG1633@2|Bacteria,COG4902@2|Bacteria,1U08K@1239|Firmicutes,4IJRT@91061|Bacilli,3NG1F@45667|Halobacillus 91061|Bacilli S Uncharacterized protein domain (DUF2202) - - - - - - - - - - - - - k141_21485_2 290402.Cbei_2042 6.39e-145 414.0 COG2207@1|root,COG3708@1|root,COG2207@2|Bacteria,COG3708@2|Bacteria,1TPI9@1239|Firmicutes,2496K@186801|Clostridia,36EDW@31979|Clostridiaceae 186801|Clostridia K transcription activator, effector binding - - - ko:K13653 - - - - ko00000,ko03000 - - - GyrI-like,HTH_18 k141_1223_1 1046714.AMRX01000006_gene3170 4.79e-289 809.0 COG1404@1|root,COG1404@2|Bacteria,1MVE6@1224|Proteobacteria,1RPCA@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Subtilase family - - - - - - - - - - - - Peptidase_S8 k141_1223_2 1046714.AMRX01000006_gene3169 4e-145 425.0 COG0464@1|root,COG0464@2|Bacteria,1MVVP@1224|Proteobacteria,1RY8X@1236|Gammaproteobacteria,46BTM@72275|Alteromonadaceae 1236|Gammaproteobacteria O ATPase family associated with various cellular activities (AAA) - - - - - - - - - - - - AAA k141_1223_3 575788.VS_1359 1.15e-251 699.0 COG1061@1|root,COG1061@2|Bacteria,1N52C@1224|Proteobacteria,1RSQN@1236|Gammaproteobacteria,1XSKU@135623|Vibrionales 135623|Vibrionales L Type III restriction enzyme, res subunit VPA1393 - - - - - - - - - - - Helicase_C,ResIII k141_1223_4 243277.VC_0177 2.03e-95 281.0 2DMZ2@1|root,32UH6@2|Bacteria,1N4V6@1224|Proteobacteria,1SBYX@1236|Gammaproteobacteria,1XY33@135623|Vibrionales 135623|Vibrionales - - - GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - - - - - - - - - - - k141_1223_5 243277.VC_0176 3.67e-48 155.0 COG1396@1|root,COG1396@2|Bacteria,1N8ZM@1224|Proteobacteria,1SD5C@1236|Gammaproteobacteria,1XYHC@135623|Vibrionales 135623|Vibrionales K Helix-turn-helix - - - - - - - - - - - - HTH_19,HTH_3 k141_1223_6 1216007.AOPM01000088_gene935 1.66e-93 288.0 2EFAC@1|root,3393A@2|Bacteria,1NX48@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_3647_1 218284.CCDN010000001_gene1271 1.41e-25 97.4 2A1JC@1|root,30PT9@2|Bacteria,1UB45@1239|Firmicutes,4IMGR@91061|Bacilli,1ZK4F@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_17925_1 218284.CCDN010000002_gene2109 1.29e-99 304.0 COG1249@1|root,COG1249@2|Bacteria,1UYJP@1239|Firmicutes,4HCWF@91061|Bacilli,1ZED9@1386|Bacillus 91061|Bacilli C Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain - - 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyr_redox_2,Pyr_redox_dim k141_6017_2 1527469.A0A076G7F3_9CAUD 2.36e-33 120.0 4QJIB@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k141_2489_1 218284.CCDN010000001_gene1001 1.91e-155 443.0 COG2195@1|root,COG2195@2|Bacteria,1TP3A@1239|Firmicutes,4HA04@91061|Bacilli,1ZBSY@1386|Bacillus 91061|Bacilli E COG2195 Di- and tripeptidases yqjE - 3.4.11.14,3.4.11.4 ko:K01258,ko:K01263 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20,Peptidase_M28 k141_13187_2 218284.CCDN010000010_gene4372 1.16e-41 137.0 COG1358@1|root,COG1358@2|Bacteria,1VFD8@1239|Firmicutes,4HNXS@91061|Bacilli,1ZIU6@1386|Bacillus 91061|Bacilli J Belongs to the eukaryotic ribosomal protein eL8 family rplGB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K07590 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L7Ae k141_13187_3 935837.JAEK01000024_gene1019 1.92e-85 253.0 COG0048@1|root,COG0048@2|Bacteria,1V1FJ@1239|Firmicutes,4HFMZ@91061|Bacilli,1ZFM9@1386|Bacillus 91061|Bacilli J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit rpsL GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02950 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosom_S12_S23 k141_106_2 218284.CCDN010000001_gene1822 1.04e-09 58.5 COG1966@1|root,COG1966@2|Bacteria,1TQN8@1239|Firmicutes,4H9SU@91061|Bacilli,1ZC6K@1386|Bacillus 91061|Bacilli T Carbon starvation protein cstA_2 - - - - - - - - - - - CstA,CstA_5TM k141_19098_1 935837.JAEK01000002_gene2005 1.93e-69 219.0 COG4221@1|root,COG4221@2|Bacteria,1TQDY@1239|Firmicutes,4HBS5@91061|Bacilli,1ZB88@1386|Bacillus 91061|Bacilli S Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short k141_23833_1 1279017.AQYJ01000028_gene2442 3.07e-72 226.0 COG1309@1|root,COG1309@2|Bacteria,1NBDY@1224|Proteobacteria,1S3CF@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator - - - - - - - - - - - - TetR_N k141_11959_1 1294265.JCM21738_3821 7.34e-161 466.0 COG2909@1|root,COG3629@1|root,COG2909@2|Bacteria,COG3629@2|Bacteria,1UWHI@1239|Firmicutes,4HADH@91061|Bacilli,1ZE89@1386|Bacillus 91061|Bacilli KT COG2909 ATP-dependent transcriptional regulator - - - ko:K03556 - - - - ko00000,ko03000 - - - AAA_16,BTAD,TPR_12,TPR_8 k141_6045_1 1116375.VEJY3_17746 1.95e-103 305.0 COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,1RSQ3@1236|Gammaproteobacteria,1XTPX@135623|Vibrionales 135623|Vibrionales P COG2897 Rhodanese-related sulfurtransferase sseA - 2.8.1.1,2.8.1.2 ko:K01011 ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122 - R01931,R03105,R03106 RC00214 ko00000,ko00001,ko01000 - - - Rhodanese k141_6045_2 1116375.VEJY3_17741 2.42e-162 471.0 COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,1RMH7@1236|Gammaproteobacteria,1XV3R@135623|Vibrionales 135623|Vibrionales S Tripartite ATP-independent periplasmic transporter, DctM component - - - - - - - - - - - - DctM k141_22688_1 218284.CCDN010000001_gene772 6.27e-49 163.0 COG1284@1|root,COG1284@2|Bacteria,1TQTP@1239|Firmicutes,4HBV2@91061|Bacilli,1ZCF3@1386|Bacillus 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2179) yqfU - - - - - - - - - - - DUF2179,YitT_membrane k141_22688_2 218284.CCDN010000001_gene773 2.61e-18 81.3 COG1121@1|root,COG1121@2|Bacteria,1TQ68@1239|Firmicutes,4HAZI@91061|Bacilli,1ZBS5@1386|Bacillus 91061|Bacilli P 'COG1121 ABC-type Mn Zn transport systems, ATPase component' zurA - - ko:K02074,ko:K09817 ko02010,map02010 M00242,M00244 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 - - ABC_tran k141_21510_1 1294265.JCM21738_443 9.22e-61 186.0 2E8H8@1|root,332VF@2|Bacteria,1VI1H@1239|Firmicutes,4HQ7K@91061|Bacilli,1ZIED@1386|Bacillus 91061|Bacilli S Late competence development protein ComFB - - - ko:K02241 - M00429 - - ko00000,ko00002,ko02044 - - - ComFB k141_21510_2 1196031.ALEG01000043_gene2251 8.14e-24 95.9 COG2188@1|root,COG2188@2|Bacteria,1TRF6@1239|Firmicutes,4HDCX@91061|Bacilli,1ZATF@1386|Bacillus 91061|Bacilli K transcriptional treR - - ko:K03486 - - - - ko00000,ko03000 - - - GntR,UTRA k141_15554_1 1052684.PPM_1767 1.62e-38 136.0 COG2320@1|root,COG2320@2|Bacteria,1V3IB@1239|Firmicutes,4HKXN@91061|Bacilli,274Z2@186822|Paenibacillaceae 91061|Bacilli S GrpB protein yqkA1 - - - - - - - - - - - GrpB k141_2490_1 42565.FP66_14290 1.17e-15 75.5 COG1766@1|root,COG1766@2|Bacteria,1MUQR@1224|Proteobacteria,1RN6T@1236|Gammaproteobacteria,1XHZ3@135619|Oceanospirillales 135619|Oceanospirillales N The M ring may be actively involved in energy transduction fliF - - ko:K02409 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 - - YscJ_FliF,YscJ_FliF_C k141_2490_2 42565.FP66_14285 9.41e-137 393.0 COG1536@1|root,COG1536@2|Bacteria,1MV9X@1224|Proteobacteria,1RM9B@1236|Gammaproteobacteria,1XHXX@135619|Oceanospirillales 135619|Oceanospirillales N FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation fliG - - ko:K02410 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02035 - - - FliG_C,FliG_M,FliG_N k141_13188_2 218284.CCDN010000007_gene3967 8.25e-76 231.0 COG4821@1|root,COG4821@2|Bacteria,1VJUP@1239|Firmicutes,4HP1J@91061|Bacilli,1ZH7S@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF2529) ywjG - - - - - - - - - - - DUF2529 k141_26250_1 768671.ThimaDRAFT_2784 3.08e-43 161.0 COG0834@1|root,COG1301@1|root,COG0834@2|Bacteria,COG1301@2|Bacteria,1P22C@1224|Proteobacteria,1RSGY@1236|Gammaproteobacteria,1WZZV@135613|Chromatiales 135613|Chromatiales U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - - - - - - - - - - SBP_bac_3,SDF k141_32167_1 1403313.AXBR01000021_gene3009 2.39e-52 172.0 COG1917@1|root,COG1917@2|Bacteria,1TSNR@1239|Firmicutes,4HENR@91061|Bacilli,1ZCSA@1386|Bacillus 91061|Bacilli S Cupin - - - - - - - - - - - - Cupin_1 k141_11960_1 1120973.AQXL01000130_gene1242 1.5e-85 258.0 COG1402@1|root,COG1402@2|Bacteria,1V0N8@1239|Firmicutes,4IDQV@91061|Bacilli,27AMS@186823|Alicyclobacillaceae 91061|Bacilli S Creatinine amidohydrolase - - 3.5.2.10 ko:K01470 ko00330,map00330 - R01884 RC00615 ko00000,ko00001,ko01000 - - - Creatininase k141_28634_1 665952.HMPREF1015_00511 1.87e-201 560.0 COG0039@1|root,COG0039@2|Bacteria,1TPSY@1239|Firmicutes,4HB0Z@91061|Bacilli,1ZC27@1386|Bacillus 91061|Bacilli C Catalyzes the reversible oxidation of malate to oxaloacetate mdh GO:0003674,GO:0003824,GO:0004470,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 1.1.1.27,1.1.1.37 ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740 R00342,R00703,R01000,R03104,R07136 RC00031,RC00044 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Ldh_1_C,Ldh_1_N k141_10758_1 1042377.AFPJ01000020_gene2087 0.0 961.0 COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,1MUV9@1224|Proteobacteria,1RN8U@1236|Gammaproteobacteria,4643Z@72275|Alteromonadaceae 1236|Gammaproteobacteria C Catalyzes the reversible hydration of fumarate to (S)- malate fumA GO:0003674,GO:0003824,GO:0004333,GO:0005488,GO:0005515,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016860,GO:0016862,GO:0016999,GO:0017144,GO:0019752,GO:0033554,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0047808,GO:0048037,GO:0050163,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 ko:K01676 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - iEC55989_1330.EC55989_1778,iPC815.YPO3335 Fumerase,Fumerase_C k141_15555_1 218284.CCDN010000001_gene79 2.54e-111 330.0 COG0849@1|root,COG0849@2|Bacteria,1TP1Z@1239|Firmicutes,4H9NF@91061|Bacilli,1ZBH1@1386|Bacillus 91061|Bacilli D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring ftsA GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032153,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0098552,GO:0098562 - ko:K03590 ko04112,map04112 - - - ko00000,ko00001,ko03036,ko04812 - - - DUF3484,FtsA,SHS2_FTSA k141_108_1 240302.BN982_00678 3.98e-25 103.0 COG0477@1|root,COG2814@2|Bacteria,1UN0M@1239|Firmicutes,4HBBP@91061|Bacilli,3NFWM@45667|Halobacillus 91061|Bacilli EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 k141_108_2 218284.CCDN010000001_gene1369 2e-38 137.0 COG4927@1|root,COG4927@2|Bacteria,1TQGX@1239|Firmicutes,4HATV@91061|Bacilli,1ZC2P@1386|Bacillus 91061|Bacilli S Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase - - - - - - - - - - - - AAT k141_21511_1 218284.CCDN010000005_gene3353 1.11e-187 553.0 COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,4HAFP@91061|Bacilli,1ZBJ3@1386|Bacillus 91061|Bacilli V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran k141_26251_1 1121943.KB899996_gene539 1.54e-73 236.0 COG0439@1|root,COG0439@2|Bacteria,1QXYJ@1224|Proteobacteria,1T4PS@1236|Gammaproteobacteria 1236|Gammaproteobacteria I ATP-grasp domain - - - - - - - - - - - - ATP-grasp_4 k141_25024_1 1340434.AXVA01000003_gene2282 1.74e-10 66.6 COG0392@1|root,COG0392@2|Bacteria,1V1W5@1239|Firmicutes,4HGDX@91061|Bacilli,1ZGE8@1386|Bacillus 91061|Bacilli S Lysylphosphatidylglycerol synthase TM region mprF - - ko:K07027 - - - - ko00000,ko02000 4.D.2 - - LPG_synthase_TM k141_25024_2 1132442.KB889752_gene2731 3.02e-118 352.0 COG0451@1|root,COG0451@2|Bacteria,1VP6I@1239|Firmicutes,4HAN7@91061|Bacilli,1ZQ48@1386|Bacillus 91061|Bacilli M NAD-dependent epimerase dehydratase - - 5.1.3.6 ko:K08679 ko00520,ko01100,map00520,map01100 - R01385 RC00289 ko00000,ko00001,ko01000 - - - Epimerase,GDP_Man_Dehyd k141_23834_1 1423321.AS29_13970 4.76e-54 178.0 29SNM@1|root,30DU7@2|Bacteria,1V3Z9@1239|Firmicutes,4HHKX@91061|Bacilli,1ZG30@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2785) - - - - - - - - - - - - DUF2785 k141_23834_2 574376.BAMA_14295 2.55e-18 79.3 COG1670@1|root,COG1670@2|Bacteria,1V972@1239|Firmicutes,4HIPE@91061|Bacilli,1ZGKC@1386|Bacillus 91061|Bacilli J Acetyltransferase (GNAT) domain - - 2.3.1.128 ko:K03789,ko:K03790 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_1,Acetyltransf_3 k141_8444_1 1205680.CAKO01000022_gene5534 3.36e-26 114.0 COG5518@1|root,COG5518@2|Bacteria,1MYGZ@1224|Proteobacteria 1224|Proteobacteria S Phage portal protein, PBSX family - - - - - - - - - - - - Phage_portal k141_14363_1 1453501.JELR01000002_gene822 2.02e-108 325.0 COG1657@1|root,COG1657@2|Bacteria,1R7YE@1224|Proteobacteria,1RYJP@1236|Gammaproteobacteria,469DF@72275|Alteromonadaceae 1236|Gammaproteobacteria I Pectic acid lyase - - - - - - - - - - - - Pec_lyase k141_19099_1 1279017.AQYJ01000028_gene2537 1.42e-189 559.0 COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,1RMWN@1236|Gammaproteobacteria,465G2@72275|Alteromonadaceae 1236|Gammaproteobacteria C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family nasA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K00372 ko00910,ko01120,map00910,map01120 M00531 R00798,R01106 RC02812 ko00000,ko00001,ko00002,ko01000 - - - Fer2_BFD,Molybdop_Fe4S4,Molybdopterin,Molydop_binding k141_28635_1 1294265.JCM21738_2559 1.61e-83 248.0 COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4HA7I@91061|Bacilli,1ZQ89@1386|Bacillus 91061|Bacilli EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components appC - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1,OppC_N k141_29794_1 218284.CCDN010000001_gene1137 3.41e-106 314.0 COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1TQCU@1239|Firmicutes,4HB60@91061|Bacilli,1ZBI9@1386|Bacillus 91061|Bacilli K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor birA - 6.3.4.15 ko:K03524 ko00780,ko01100,map00780,map01100 - R01074,R05145 RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko01000,ko03000 - - - BPL_C,BPL_LplA_LipB,HTH_11 k141_7201_2 1238450.VIBNISOn1_1670026 8.17e-256 706.0 COG2182@1|root,COG2182@2|Bacteria,1N9AE@1224|Proteobacteria,1RN4E@1236|Gammaproteobacteria,1XSZ5@135623|Vibrionales 135623|Vibrionales G Bacterial extracellular solute-binding protein - - - ko:K15770 ko02010,map02010 M00491 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.16,3.A.1.1.2 - - SBP_bac_8 k141_7201_3 1238450.VIBNISOn1_1670027 1.33e-225 626.0 COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,1RM9E@1236|Gammaproteobacteria,1XSE0@135623|Vibrionales 1236|Gammaproteobacteria P Belongs to the ABC transporter superfamily malK - - ko:K10111,ko:K10191 ko02010,map02010 M00194,M00199,M00200,M00204,M00207,M00491 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.1,3.A.1.1.4 - - ABC_tran,TOBE_2 k141_7201_4 1238450.VIBNISOn1_1670028 1.72e-186 524.0 COG1609@1|root,COG1609@2|Bacteria,1N8ZA@1224|Proteobacteria,1RSGV@1236|Gammaproteobacteria,1XSKZ@135623|Vibrionales 135623|Vibrionales K COG1609 Transcriptional regulators ebgR - - ko:K12113 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 k141_15556_1 1042377.AFPJ01000044_gene644 1.57e-45 167.0 COG1680@1|root,COG1680@2|Bacteria,1MWHS@1224|Proteobacteria,1RRQF@1236|Gammaproteobacteria,46627@72275|Alteromonadaceae 1236|Gammaproteobacteria V COG1680 Beta-lactamase class C and other penicillin binding - - - - - - - - - - - - ASH,Beta-lactamase k141_110_1 1378168.N510_01622 5.8e-28 114.0 COG1228@1|root,COG1228@2|Bacteria,1TP2J@1239|Firmicutes 1239|Firmicutes Q imidazolone-5-propionate hydrolase hutI - 3.5.2.7 ko:K01468 ko00340,ko01100,map00340,map01100 M00045 R02288 RC00683 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU39370 Amidohydro_1,Amidohydro_3 k141_17947_1 1042377.AFPJ01000008_gene2008 1.3e-101 315.0 COG0388@1|root,COG0388@2|Bacteria,1MXG5@1224|Proteobacteria 1224|Proteobacteria T Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - - - - - - - - - - CN_hydrolase k141_21512_1 1444309.JAQG01000097_gene4133 6.2e-14 70.1 COG0583@1|root,COG0583@2|Bacteria,1TST3@1239|Firmicutes,4HDBC@91061|Bacilli,26TJF@186822|Paenibacillaceae 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_21512_2 218284.CCDN010000002_gene2744 3.63e-120 367.0 COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,4HE6Q@91061|Bacilli,1ZFF0@1386|Bacillus 91061|Bacilli S ABC-2 family transporter protein - - - ko:K01421 - - - - ko00000 - - - ABC2_membrane_3 k141_22689_1 218284.CCDN010000005_gene3366 2.69e-187 526.0 COG3594@1|root,COG3594@2|Bacteria,1TPGY@1239|Firmicutes,4HCER@91061|Bacilli,1ZDAV@1386|Bacillus 91061|Bacilli G COG3594 Fucose 4-O-acetylase and related acetyltransferases ykrP - - - - - - - - - - - Acyl_transf_3 k141_29795_1 1121422.AUMW01000038_gene3007 3.11e-51 172.0 COG0491@1|root,COG0491@2|Bacteria,1TR4H@1239|Firmicutes,24KW2@186801|Clostridia,262BD@186807|Peptococcaceae 186801|Clostridia S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B k141_33367_1 1294265.JCM21738_3797 6.05e-120 363.0 COG1305@1|root,COG1305@2|Bacteria,1TP8K@1239|Firmicutes,4HB2E@91061|Bacilli,1ZBUN@1386|Bacillus 91061|Bacilli E COG1305 Transglutaminase-like enzymes yebA - - - - - - - - - - - DUF4129,Transglut_core k141_8447_1 218284.CCDN010000002_gene2138 7.86e-146 420.0 COG3844@1|root,COG3844@2|Bacteria,1TQ8V@1239|Firmicutes,4HBE8@91061|Bacilli,1ZBCN@1386|Bacillus 91061|Bacilli E Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively kynU GO:0003674,GO:0003824,GO:0016787,GO:0016822,GO:0016823,GO:0030429 3.7.1.3 ko:K01556 ko00380,ko01100,map00380,map01100 M00038 R00987,R02668,R03936 RC00284,RC00415 ko00000,ko00001,ko00002,ko01000 - - - Aminotran_5 k141_6050_1 218284.CCDN010000010_gene4388 1.48e-192 543.0 COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,4HAKH@91061|Bacilli,1ZAWK@1386|Bacillus 91061|Bacilli J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) gltX GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0009986,GO:0030246,GO:0030247,GO:0044464,GO:2001065 6.1.1.24 ko:K09698 ko00970,ko01100,map00970,map01100 M00360 R03651,R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iSB619.SA_RS02860 tRNA-synt_1c k141_11961_1 313598.MED152_07970 0.000485 51.6 COG1361@1|root,COG1470@1|root,COG1361@2|Bacteria,COG1470@2|Bacteria,4NMB8@976|Bacteroidetes,1I0EW@117743|Flavobacteriia 976|Bacteroidetes M Domain of unknown function DUF11 - - - - - - - - - - - - CHU_C,DUF11,He_PIG k141_28637_1 218284.CCDN010000001_gene1870 2.03e-74 246.0 COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,4H9WA@91061|Bacilli,1ZANX@1386|Bacillus 91061|Bacilli D Belongs to the FtsK SpoIIIE SftA family ftsK GO:0000003,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma k141_34567_1 1279017.AQYJ01000027_gene1649 0.0 1241.0 COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,1RNJI@1236|Gammaproteobacteria,4649F@72275|Alteromonadaceae 1236|Gammaproteobacteria L it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction rep GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022402,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044786,GO:0044787,GO:0046483,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 ko:K03656,ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C k141_34567_2 1279017.AQYJ01000027_gene1648 9.7e-39 130.0 COG1670@1|root,COG1670@2|Bacteria,1N9F9@1224|Proteobacteria,1SCFK@1236|Gammaproteobacteria,46BDC@72275|Alteromonadaceae 1236|Gammaproteobacteria J Protein of unknown function (DUF3565) - - - - - - - - - - - - DUF3565 k141_34567_3 1279017.AQYJ01000027_gene1647 5.29e-87 258.0 COG1671@1|root,COG1671@2|Bacteria,1RCZA@1224|Proteobacteria,1S3QM@1236|Gammaproteobacteria,467BK@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the UPF0178 family yaiI - - ko:K09768 - - - - ko00000 - - - DUF188 k141_34567_4 411467.BACCAP_04846 2.28e-05 50.1 COG0454@1|root,COG0456@2|Bacteria,1UFYN@1239|Firmicutes,24RVV@186801|Clostridia 186801|Clostridia K FR47-like protein - - - - - - - - - - - - - k141_34567_5 379731.PST_2698 2.87e-69 216.0 COG1670@1|root,COG1670@2|Bacteria,1RCX2@1224|Proteobacteria,1S42B@1236|Gammaproteobacteria,1Z1MN@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins - - 2.3.1.128 ko:K03790 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 k141_34567_6 1500301.JQMF01000015_gene4850 1.98e-29 112.0 COG2020@1|root,COG2020@2|Bacteria,1MZ7S@1224|Proteobacteria,2UAQH@28211|Alphaproteobacteria,4BMR4@82115|Rhizobiaceae 28211|Alphaproteobacteria O Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - - - - - - - - - - PEMT k141_34567_7 1453501.JELR01000002_gene1004 3.64e-102 311.0 COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,1RMB9@1236|Gammaproteobacteria,464ZX@72275|Alteromonadaceae 1236|Gammaproteobacteria O ATPase with chaperone activity comM GO:0003674,GO:0003824,GO:0004176,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0042623,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - ko:K07391 - - - - ko00000 - - - ChlI,Mg_chelatase,Mg_chelatase_C k141_25025_1 1042377.AFPJ01000005_gene2438 2.19e-162 465.0 COG1271@1|root,COG1271@2|Bacteria,1MV60@1224|Proteobacteria,1RN2U@1236|Gammaproteobacteria,4642Q@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1271 Cytochrome bd-type quinol oxidase, subunit 1 cydA - 1.10.3.14 ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - Cyt_bd_oxida_I k141_16700_1 1517416.IDAT_06815 4.33e-178 518.0 COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,1RP7E@1236|Gammaproteobacteria,2QF6Q@267893|Idiomarinaceae 1236|Gammaproteobacteria M Amidase gatAX - 3.5.1.4,6.3.5.6,6.3.5.7 ko:K01426,ko:K02433 ko00330,ko00360,ko00380,ko00627,ko00643,ko00970,ko01100,ko01120,map00330,map00360,map00380,map00627,map00643,map00970,map01100,map01120 - R02540,R03096,R03180,R03905,R03909,R04212,R05551,R05590 RC00010,RC00100,RC00950,RC01025 ko00000,ko00001,ko01000,ko03029 - - - Amidase k141_16700_2 1453501.JELR01000002_gene161 9.55e-44 144.0 2D7C6@1|root,32TNS@2|Bacteria,1MZUP@1224|Proteobacteria,1SA42@1236|Gammaproteobacteria,46CTJ@72275|Alteromonadaceae 1236|Gammaproteobacteria S aminopeptidase IV02_13490 - - - - - - - - - - - - k141_16700_3 1453501.JELR01000002_gene162 2.59e-147 421.0 COG2981@1|root,COG2981@2|Bacteria,1MVFT@1224|Proteobacteria,1RMQT@1236|Gammaproteobacteria,4671M@72275|Alteromonadaceae 1236|Gammaproteobacteria E High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway cysZ GO:0000096,GO:0000097,GO:0000103,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006520,GO:0006534,GO:0006790,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0008150,GO:0008152,GO:0008271,GO:0008272,GO:0008324,GO:0008509,GO:0008512,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009675,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015103,GO:0015116,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015296,GO:0015318,GO:0015672,GO:0015698,GO:0016020,GO:0016021,GO:0016053,GO:0019344,GO:0019752,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034220,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044425,GO:0044459,GO:0044464,GO:0046394,GO:0051179,GO:0051234,GO:0055085,GO:0071704,GO:0071944,GO:0072348,GO:0098655,GO:0098656,GO:0098660,GO:0098661,GO:0098662,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901682,GO:1902358,GO:1902600 - ko:K06203 - - - - ko00000 - - iJR904.b2413,iYL1228.KPN_02760 EI24 k141_16700_4 1453501.JELR01000002_gene212 5.97e-94 283.0 COG3300@1|root,COG3300@2|Bacteria,1QUST@1224|Proteobacteria,1S7RZ@1236|Gammaproteobacteria,46877@72275|Alteromonadaceae 1236|Gammaproteobacteria T Bacterial signalling protein N terminal repeat - - - - - - - - - - - - MHYT k141_15558_1 218284.CCDN010000002_gene2860 2.95e-41 142.0 2DWNN@1|root,3417F@2|Bacteria,1W28F@1239|Firmicutes,4I1N7@91061|Bacilli,1ZHY2@1386|Bacillus 91061|Bacilli - - - - 1.14.13.238 ko:K22344 - - - - ko00000,ko01000 - - - - k141_17949_1 1385510.N781_15735 1.67e-23 96.7 COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,4HARE@91061|Bacilli 91061|Bacilli C reductase ytbE - - - - - - - - - - - Aldo_ket_red k141_4851_2 218284.CCDN010000001_gene1407 8.97e-158 445.0 COG0730@1|root,COG0730@2|Bacteria,1TRIE@1239|Firmicutes,4HARW@91061|Bacilli,1ZC6G@1386|Bacillus 91061|Bacilli S membrane transporter protein yrkJ - - ko:K07090 - - - - ko00000 - - - TauE k141_4851_3 218284.CCDN010000001_gene1406 1.7e-87 266.0 COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,1TPE2@1239|Firmicutes,4H9WH@91061|Bacilli,1ZCD8@1386|Bacillus 91061|Bacilli P Rhodanese Homology Domain yrkH - - - - - - - - - - - Lactamase_B,Rhodanese k141_7205_1 406124.ACPC01000047_gene1752 1.89e-94 290.0 COG1292@1|root,COG1292@2|Bacteria,1TRS6@1239|Firmicutes,4HA7U@91061|Bacilli,1ZBRN@1386|Bacillus 91061|Bacilli M Belongs to the BCCT transporter (TC 2.A.15) family - - - ko:K05020 - - - - ko00000,ko02000 2.A.15.1.1,2.A.15.1.11 - - BCCT k141_20279_2 223926.28807833 1.5e-127 362.0 COG1949@1|root,COG1949@2|Bacteria,1R9WX@1224|Proteobacteria,1S217@1236|Gammaproteobacteria,1XSRQ@135623|Vibrionales 135623|Vibrionales A 3'-to-5' exoribonuclease specific for small oligoribonucleotides orn GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - ko:K13288 ko03008,map03008 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - RNase_T k141_25043_1 218284.CCDN010000001_gene1635 7.66e-60 195.0 COG0860@1|root,COG0860@2|Bacteria,1TSFS@1239|Firmicutes,4HACZ@91061|Bacilli,1ZAV0@1386|Bacillus 91061|Bacilli M stage II sporulation protein P - - - ko:K06385 - - - - ko00000 - - - SpoIIP k141_25043_2 218284.CCDN010000001_gene316 2.77e-07 51.2 29RJD@1|root,30CNG@2|Bacteria,1UA4U@1239|Firmicutes,4IKF4@91061|Bacilli,1ZGTM@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_8466_1 218284.CCDN010000007_gene3985 2.8e-80 240.0 COG0394@1|root,COG0394@2|Bacteria,1VA05@1239|Firmicutes,4HKBQ@91061|Bacilli,1ZH51@1386|Bacillus 91061|Bacilli T Belongs to the low molecular weight phosphotyrosine protein phosphatase family ywlE - 3.1.3.48,3.9.1.2 ko:K01104,ko:K20201 - - - - ko00000,ko01000 - - - LMWPc k141_34764_1 218284.CCDN010000001_gene1751 1.2e-119 352.0 COG0626@1|root,COG0626@2|Bacteria,1TPC7@1239|Firmicutes,4HAFQ@91061|Bacilli,1ZAR9@1386|Bacillus 91061|Bacilli E cystathionine metC GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0016740,GO:0016765,GO:0016829,GO:0016846 4.4.1.8 ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU11880 Cys_Met_Meta_PP k141_10964_1 218284.CCDN010000005_gene3282 7.42e-200 558.0 COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4H9PZ@91061|Bacilli,1ZC9B@1386|Bacillus 91061|Bacilli EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components oppC - - ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - BPD_transp_1,OppC_N k141_26586_1 1227360.C176_13872 6.36e-11 62.8 COG1309@1|root,COG1309@2|Bacteria,1V45P@1239|Firmicutes,4HHJU@91061|Bacilli,26FEA@186818|Planococcaceae 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - TetR_C_8,TetR_N k141_5015_1 911008.GLAD_03771 5.01e-92 293.0 COG0699@1|root,COG0699@2|Bacteria,1Q9KV@1224|Proteobacteria,1SIK3@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Dynamin family - - - - - - - - - - - - Dynamin_N k141_29930_3 1042377.AFPJ01000006_gene2111 0.0 2601.0 COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,1RPYH@1236|Gammaproteobacteria,46403@72275|Alteromonadaceae 1236|Gammaproteobacteria K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoC GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 k141_29930_4 1453501.JELR01000005_gene1714 0.0 2439.0 COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,1RMK0@1236|Gammaproteobacteria,464QF@72275|Alteromonadaceae 1236|Gammaproteobacteria K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoB GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 k141_7425_2 1453501.JELR01000001_gene3113 6.12e-121 345.0 COG0221@1|root,COG0221@2|Bacteria,1RA2F@1224|Proteobacteria,1RPVD@1236|Gammaproteobacteria,4647K@72275|Alteromonadaceae 1236|Gammaproteobacteria C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions ppa GO:0000287,GO:0003674,GO:0003824,GO:0004427,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006793,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050355 3.6.1.1 ko:K01507 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - iJN746.PP_0538,iPC815.YPO3521 Pyrophosphatase k141_7425_3 1042377.AFPJ01000010_gene1421 9.4e-46 155.0 COG2013@1|root,COG2013@2|Bacteria,1R28E@1224|Proteobacteria,1T5IR@1236|Gammaproteobacteria,46DC3@72275|Alteromonadaceae 1236|Gammaproteobacteria S TIGRFAM TIGR00266 family protein - - - - - - - - - - - - - k141_7425_4 1453501.JELR01000001_gene3116 8.17e-144 411.0 COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,1RNCA@1236|Gammaproteobacteria,4663K@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG1045 Serine acetyltransferase cysE GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009001,GO:0009058,GO:0009069,GO:0009070,GO:0009314,GO:0009333,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016053,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019344,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.3.1.30 ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 M00021 R00586 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,SATase_N k141_7425_5 1042377.AFPJ01000010_gene1423 9.24e-110 322.0 COG1876@1|root,COG1876@2|Bacteria,1N2IC@1224|Proteobacteria,1S0DU@1236|Gammaproteobacteria,4679R@72275|Alteromonadaceae 1236|Gammaproteobacteria M D-alanyl-D-alanine carboxypeptidase vanY - - - - - - - - - - - VanY k141_7425_6 1279017.AQYJ01000024_gene886 4.34e-47 152.0 COG3070@1|root,32UKE@2|Bacteria,1QTSU@1224|Proteobacteria,1T1G1@1236|Gammaproteobacteria,468KE@72275|Alteromonadaceae 1236|Gammaproteobacteria K TfoX C-terminal domain - - - ko:K07343 - - - - ko00000 - - - TfoX_C k141_7425_7 1453501.JELR01000001_gene3119 4.85e-171 482.0 COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,1RMN0@1236|Gammaproteobacteria,464V0@72275|Alteromonadaceae 1236|Gammaproteobacteria O Belongs to the peptidase M48B family htpX GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0016020,GO:0016021,GO:0016787,GO:0019538,GO:0031224,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044425,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 - ko:K03799 - M00743 - - ko00000,ko00002,ko01000,ko01002 - - - Peptidase_M48 k141_7425_8 1453501.JELR01000001_gene3120 1.81e-197 554.0 COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN3T@1236|Gammaproteobacteria,4666M@72275|Alteromonadaceae 1236|Gammaproteobacteria O Trypsin degP - - - - - - - - - - - PDZ_2,Trypsin_2 k141_7425_9 1279017.AQYJ01000024_gene883 6.74e-76 226.0 COG2146@1|root,COG2146@2|Bacteria,1N72F@1224|Proteobacteria,1SD0G@1236|Gammaproteobacteria,468PW@72275|Alteromonadaceae 1236|Gammaproteobacteria P Rieske [2Fe-2S] domain - - - - - - - - - - - - Rieske k141_7425_10 1279017.AQYJ01000024_gene882 3.06e-130 374.0 COG1489@1|root,COG1489@2|Bacteria,1MUC3@1224|Proteobacteria,1RQ95@1236|Gammaproteobacteria,466BU@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the SfsA family sfsA GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005975,GO:0006355,GO:0008150,GO:0008152,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0044238,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - ko:K06206 - - - - ko00000 - - - SfsA k141_7425_11 1279017.AQYJ01000024_gene881 5.82e-94 275.0 COG1734@1|root,COG1734@2|Bacteria,1RD08@1224|Proteobacteria,1S47H@1236|Gammaproteobacteria,466DH@72275|Alteromonadaceae 1236|Gammaproteobacteria T Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression dksA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K06204 ko02026,map02026 - - - ko00000,ko00001,ko03000,ko03009,ko03021 - - - zf-dskA_traR k141_7425_12 1453501.JELR01000001_gene3124 2.92e-131 381.0 COG0008@1|root,COG0008@2|Bacteria,1MUN7@1224|Proteobacteria,1RMYQ@1236|Gammaproteobacteria,466ES@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon gluQ GO:0000166,GO:0002097,GO:0003674,GO:0005488,GO:0005524,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 - ko:K01894 - - - - ko00000,ko01000,ko01007,ko03016 - - - tRNA-synt_1c k141_20420_1 218284.CCDN010000001_gene801 1.19e-107 324.0 COG0457@1|root,COG0705@1|root,COG0457@2|Bacteria,COG0705@2|Bacteria,1TQXT@1239|Firmicutes,4HCDF@91061|Bacilli,1ZBV7@1386|Bacillus 91061|Bacilli O membrane protein (homolog of Drosophila rhomboid) gluP - 3.4.21.105 ko:K19225 - - - - ko00000,ko01000,ko01002 - - - Rhomboid,TPR_2,TPR_8 k141_25259_1 223926.28805290 5.85e-142 415.0 COG0729@1|root,COG0729@2|Bacteria,1MUKM@1224|Proteobacteria,1RNQ3@1236|Gammaproteobacteria,1XV1N@135623|Vibrionales 135623|Vibrionales M COG0729 Outer membrane protein ytfM - - ko:K07278 - - - - ko00000,ko02000 1.B.33.2.4 - - Bac_surface_Ag,POTRA,POTRA_TamA_1 k141_12250_1 218284.CCDN010000004_gene3153 1.38e-113 338.0 COG0189@1|root,COG0189@2|Bacteria,1V1EV@1239|Firmicutes,4HFNI@91061|Bacilli,1ZBM5@1386|Bacillus 91061|Bacilli HJ YheC/D like ATP-grasp - - - - - - - - - - - - ATPgrasp_YheCD k141_12250_2 218284.CCDN010000004_gene3154 2.65e-84 258.0 COG4399@1|root,COG4399@2|Bacteria,1TQDH@1239|Firmicutes,4HA30@91061|Bacilli,1ZB1W@1386|Bacillus 91061|Bacilli S Belongs to the UPF0754 family yheB - - - - - - - - - - - DUF445 k141_37069_1 1304284.L21TH_0268 2.67e-26 111.0 COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,1V9Y7@1239|Firmicutes,24A8B@186801|Clostridia,36E8P@31979|Clostridiaceae 186801|Clostridia T Diguanylate cyclase - - - - - - - - - - - - AAA_16,GGDEF,Pkinase,TPR_12,TPR_8 k141_27559_1 338963.Pcar_2149 2.56e-62 211.0 COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria,43TCZ@69541|Desulfuromonadales 28221|Deltaproteobacteria NU General secretory system II, protein E domain protein pilB - - ko:K02652 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE,T2SSE_N,cNMP_binding k141_16969_1 1294265.JCM21738_676 3.35e-114 336.0 COG0473@1|root,COG0473@2|Bacteria,1TPEM@1239|Firmicutes,4HATP@91061|Bacilli,1ZB3Y@1386|Bacillus 91061|Bacilli CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate leuB GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R00994,R04426,R10052 RC00084,RC00417,RC03036 br01601,ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU28270 Iso_dh k141_24024_1 1294265.JCM21738_1610 7.19e-15 72.8 COG1173@1|root,COG1173@2|Bacteria,1V21B@1239|Firmicutes,4HDPU@91061|Bacilli,1ZEQ7@1386|Bacillus 91061|Bacilli EP Binding-protein-dependent transport system inner membrane component - - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1,Peptidase_M1 k141_24024_2 1294265.JCM21738_1609 4.9e-47 155.0 COG0601@1|root,COG0601@2|Bacteria,1TRW4@1239|Firmicutes,4HEGZ@91061|Bacilli,1ZH5U@1386|Bacillus 91061|Bacilli EP Binding-protein-dependent transport system inner membrane component - - - ko:K02033 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 k141_33545_1 1415780.JPOG01000001_gene1953 1.27e-24 102.0 COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RPIP@1236|Gammaproteobacteria,1X3P5@135614|Xanthomonadales 1236|Gammaproteobacteria T Sterol-sensing domain of SREBP cleavage-activation - - - ko:K07003 - - - - ko00000 - - - LolA_like,MMPL,Polyketide_cyc2 k141_33545_2 1415780.JPOG01000001_gene1954 1.25e-57 195.0 COG3103@1|root,COG3103@2|Bacteria,1MVX1@1224|Proteobacteria,1S3BH@1236|Gammaproteobacteria 1236|Gammaproteobacteria T N-Acetylmuramoyl-L-alanine amidase - - - - - - - - - - - - AMIN k141_10965_1 218284.CCDN010000001_gene1685 1.42e-97 313.0 COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,4HC3Y@91061|Bacilli,1ZCCY@1386|Bacillus 91061|Bacilli V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family yerP1 - - - - - - - - - - - ACR_tran k141_2685_1 1122172.KB890273_gene689 2.18e-32 119.0 COG3727@1|root,COG3727@2|Bacteria 2|Bacteria L T/G mismatch-specific endonuclease activity vsr - - ko:K07458 - - - - ko00000,ko01000,ko03400 - - - Vsr k141_2685_2 1205908.AKXW01000108_gene1282 1.98e-29 112.0 COG2273@1|root,COG2273@2|Bacteria,1RANY@1224|Proteobacteria,1SIGK@1236|Gammaproteobacteria,1XX6K@135623|Vibrionales 135623|Vibrionales G Exported glycosyl hydrolase, family 16 - - - - - - - - - - - - Glyco_hydro_16 k141_19286_1 1121090.KB894706_gene1004 5.89e-48 167.0 COG3332@1|root,COG3332@2|Bacteria,1UYHE@1239|Firmicutes,4HCA1@91061|Bacilli,1ZCCC@1386|Bacillus 91061|Bacilli S Transport and Golgi organisation 2 - - - - - - - - - - - - TANGO2 k141_19286_2 1453501.JELR01000002_gene680 4.1e-267 750.0 COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,1RQR7@1236|Gammaproteobacteria,4668G@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria ycbB GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0006508,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0008236,GO:0008238,GO:0009273,GO:0009987,GO:0016740,GO:0016746,GO:0016755,GO:0016787,GO:0016807,GO:0017171,GO:0019538,GO:0033554,GO:0042546,GO:0043164,GO:0043170,GO:0044036,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0050896,GO:0051716,GO:0070004,GO:0070008,GO:0070011,GO:0071554,GO:0071704,GO:0071840,GO:0071972,GO:0140096,GO:1901564 - ko:K21470 - - - - ko00000,ko01002,ko01011 - - - PG_binding_1,YkuD k141_25260_1 983545.Glaag_0103 9.07e-80 249.0 COG1957@1|root,COG1957@2|Bacteria,1MUIW@1224|Proteobacteria,1RSCY@1236|Gammaproteobacteria,468AT@72275|Alteromonadaceae 1236|Gammaproteobacteria G Inosine-uridine preferring nucleoside hydrolase rihA GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006152,GO:0006213,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008477,GO:0009056,GO:0009116,GO:0009119,GO:0009164,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019439,GO:0034641,GO:0034655,GO:0034656,GO:0042278,GO:0042454,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0045437,GO:0046131,GO:0046133,GO:0046135,GO:0046483,GO:0046700,GO:0046872,GO:0047405,GO:0050263,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901657,GO:1901658 3.2.2.1 ko:K01239,ko:K01250 ko00230,ko00760,ko01100,map00230,map00760,map01100 - R01245,R01273,R01677,R01770,R02143 RC00033,RC00063,RC00122,RC00318,RC00485 ko00000,ko00001,ko01000 - - iEC55989_1330.EC55989_0645,iECSE_1348.ECSE_0721,iEcE24377_1341.EcE24377A_0679,iSbBS512_1146.SbBS512_E0598 IU_nuc_hydro k141_5016_1 218284.CCDN010000001_gene1966 2.97e-169 475.0 COG1082@1|root,COG1082@2|Bacteria,1TPJT@1239|Firmicutes,4H9KJ@91061|Bacilli,1ZCIZ@1386|Bacillus 91061|Bacilli G Xylose isomerase - - - - - - - - - - - - AP_endonuc_2,AP_endonuc_2_N k141_27560_1 218284.CCDN010000011_gene4423 8.9e-84 268.0 COG1305@1|root,COG1305@2|Bacteria,1TP8K@1239|Firmicutes,4HB2E@91061|Bacilli,1ZBUN@1386|Bacillus 91061|Bacilli E COG1305 Transglutaminase-like enzymes yebA - - - - - - - - - - - DUF4129,Transglut_core k141_7426_1 1453501.JELR01000002_gene1525 3.42e-55 181.0 COG0784@1|root,COG3710@1|root,COG0784@2|Bacteria,COG3710@2|Bacteria,1QVVG@1224|Proteobacteria,1S4NY@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Transcriptional regulator, CadC - - - - - - - - - - - - Response_reg,Trans_reg_C k141_28868_1 1116375.VEJY3_20421 3.58e-119 342.0 COG3485@1|root,COG3485@2|Bacteria,1MUYX@1224|Proteobacteria,1RQHU@1236|Gammaproteobacteria,1XXBD@135623|Vibrionales 135623|Vibrionales Q Protocatechuate 3,4-dioxygenase beta - - 1.13.11.3 ko:K00449 ko00362,ko00624,ko01100,ko01120,ko01220,map00362,map00624,map01100,map01120,map01220 - R01631,R03549 RC00388,RC00953 br01602,ko00000,ko00001,ko01000 - - - Dioxygenase_C k141_28868_2 1298865.H978DRAFT_1814 9.95e-83 253.0 2FCBS@1|root,344FC@2|Bacteria,1P3N6@1224|Proteobacteria,1SRW4@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_28868_3 1298865.H978DRAFT_1815 1.79e-86 270.0 28YBG@1|root,2ZK63@2|Bacteria,1P6RP@1224|Proteobacteria,1SVZ4@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_28868_4 1298865.H978DRAFT_1816 1.36e-184 537.0 2EWCR@1|root,33PRE@2|Bacteria,1NTZZ@1224|Proteobacteria,1SMXZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_18180_2 479431.Namu_3915 2.24e-10 64.7 COG3832@1|root,COG3832@2|Bacteria,2IBWM@201174|Actinobacteria,4EWJS@85013|Frankiales 201174|Actinobacteria J glyoxalase III activity - - - - - - - - - - - - - k141_16970_2 67275.JOAP01000006_gene6215 4.06e-11 64.3 COG3595@1|root,COG3595@2|Bacteria,2GKT3@201174|Actinobacteria 201174|Actinobacteria S domain, Protein - - - - - - - - - - - - DUF4097 k141_24057_2 1453501.JELR01000002_gene1360 3.51e-184 534.0 COG4206@1|root,COG4206@2|Bacteria,1MUZG@1224|Proteobacteria,1RP7I@1236|Gammaproteobacteria,463Z2@72275|Alteromonadaceae 1236|Gammaproteobacteria H COG1629 Outer membrane receptor proteins, mostly Fe transport - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - CarboxypepD_reg,Plug,TonB_dep_Rec k141_33578_1 42565.FP66_13495 2.28e-118 365.0 COG0591@1|root,COG4191@1|root,COG0591@2|Bacteria,COG4191@2|Bacteria,1QTSW@1224|Proteobacteria,1T1G2@1236|Gammaproteobacteria,1XHSP@135619|Oceanospirillales 135619|Oceanospirillales T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,PAS k141_9785_1 1116375.VEJY3_10105 8.65e-150 429.0 COG3489@1|root,COG3489@2|Bacteria,1MWBW@1224|Proteobacteria,1S2FI@1236|Gammaproteobacteria,1XSGX@135623|Vibrionales 135623|Vibrionales S periplasmic lipoprotein - - - ko:K07338 - - - - ko00000 - - - Peptidase_M75 k141_9785_2 1116375.VEJY3_10110 1.48e-133 389.0 COG3488@1|root,COG3488@2|Bacteria,1MXUW@1224|Proteobacteria,1RRXK@1236|Gammaproteobacteria,1XTDS@135623|Vibrionales 135623|Vibrionales C Thiol oxidoreductase - - - - - - - - - - - - DHOR k141_26629_1 218284.CCDN010000005_gene3310 5.38e-138 397.0 COG0332@1|root,COG0332@2|Bacteria,1TPDE@1239|Firmicutes,4H9W9@91061|Bacilli,1ZAW8@1386|Bacillus 91061|Bacilli I Stage V sporulation protein AD spoVAD - - ko:K06406 - - - - ko00000 - - - SpoVAD k141_18204_1 1415754.JQMK01000002_gene2275 6.42e-107 319.0 28IWY@1|root,2Z8V1@2|Bacteria,1R9PZ@1224|Proteobacteria,1SGUD@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_18204_2 1346330.M472_19100 8.96e-08 57.0 COG4632@1|root,COG4632@2|Bacteria,4NR1M@976|Bacteroidetes,1ITPU@117747|Sphingobacteriia 976|Bacteroidetes G COGs COG4632 Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase - - - - - - - - - - - - Metallophos,NAGPA,fn3 k141_10983_1 218284.CCDN010000002_gene2026 6.09e-206 571.0 COG1597@1|root,COG1597@2|Bacteria,1TQAU@1239|Firmicutes,4H9WD@91061|Bacilli,1ZBPD@1386|Bacillus 91061|Bacilli I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase dagK GO:0003674,GO:0003824,GO:0004143,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237 2.7.1.107 ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 - R02240 RC00002,RC00017 ko00000,ko00001,ko01000 - - - DAGK_cat k141_31238_1 1116375.VEJY3_19426 1.68e-215 598.0 COG1638@1|root,COG1638@2|Bacteria,1QJDA@1224|Proteobacteria,1RXJZ@1236|Gammaproteobacteria,1Y059@135623|Vibrionales 135623|Vibrionales G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component - - - - - - - - - - - - DctP k141_31238_2 1116375.VEJY3_19421 6.92e-32 120.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,1RXSY@1236|Gammaproteobacteria,1XZX7@135623|Vibrionales 135623|Vibrionales G COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - - - - - - - - - - DctM k141_35919_1 319224.Sputcn32_2062 5.57e-100 306.0 COG0129@1|root,COG0129@2|Bacteria,1MV4I@1224|Proteobacteria,1RRRD@1236|Gammaproteobacteria,2QD87@267890|Shewanellaceae 1236|Gammaproteobacteria EG Belongs to the IlvD Edd family IV02_10650 - 4.2.1.25,4.2.1.9 ko:K01687,ko:K13875 ko00053,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00053,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R01209,R02522,R04441,R05070 RC00468,RC00543,RC01714 ko00000,ko00001,ko00002,ko01000 - - - ILVD_EDD k141_1442_1 218284.CCDN010000001_gene605 3.19e-166 473.0 COG0001@1|root,COG0001@2|Bacteria,1TPNH@1239|Firmicutes,4HANQ@91061|Bacilli,1ZBUT@1386|Bacillus 91061|Bacilli H Glutamate-1-semialdehyde aminotransferase hemL - 5.4.3.8 ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02272 RC00677 ko00000,ko00001,ko00002,ko01000,ko01007 - - iSB619.SA_RS08395 Aminotran_3 k141_9786_1 1453501.JELR01000002_gene1399 6.38e-99 296.0 COG2269@1|root,COG2269@2|Bacteria,1MU97@1224|Proteobacteria,1RMR9@1236|Gammaproteobacteria,4645R@72275|Alteromonadaceae 1236|Gammaproteobacteria J COG2269 Truncated, possibly inactive, lysyl-tRNA synthetase (class II) epmA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006430,GO:0006464,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016746,GO:0016755,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052868,GO:0071704,GO:0071915,GO:0072580,GO:0072581,GO:0090304,GO:0140096,GO:1901360,GO:1901564,GO:1901566,GO:1901576 - ko:K04568 - - - - ko00000,ko01000,ko03012 - - - tRNA-synt_2 k141_3940_1 1437448.AZRT01000157_gene331 1.64e-72 226.0 COG3335@1|root,COG3335@2|Bacteria,1RB1C@1224|Proteobacteria,2U367@28211|Alphaproteobacteria 28211|Alphaproteobacteria L DDE superfamily endonuclease - - - - - - - - - - - - DDE_3 k141_8630_1 1279017.AQYJ01000029_gene3475 1.18e-108 342.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,464D1@72275|Alteromonadaceae 1236|Gammaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K18138 ko01501,ko01503,map01501,map01503 M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2 - - ACR_tran k141_8630_2 1279017.AQYJ01000029_gene3474 7.5e-168 479.0 COG0845@1|root,COG0845@2|Bacteria,1R4JA@1224|Proteobacteria,1RPS5@1236|Gammaproteobacteria,46CMY@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K18302,ko:K21136,ko:K21137 - M00642,M00821 - - ko00000,ko00002,ko01504,ko02000 2.A.6.2,2.A.6.2.27,8.A.1 - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 k141_8630_3 1279017.AQYJ01000029_gene3473 4.84e-69 214.0 COG1309@1|root,COG1309@2|Bacteria,1N6TK@1224|Proteobacteria,1SCNY@1236|Gammaproteobacteria,4692V@72275|Alteromonadaceae 1236|Gammaproteobacteria K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N k141_8630_4 1122599.AUGR01000026_gene1263 0.0 1123.0 COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,1RN6K@1236|Gammaproteobacteria,1XHJR@135619|Oceanospirillales 1236|Gammaproteobacteria C Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) aceE - 1.2.4.1 ko:K00163 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - Transketolase_N k141_8630_5 1117647.M5M_10785 1.16e-232 646.0 COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,1RMCV@1236|Gammaproteobacteria,1J4WT@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide mdeA - 2.5.1.48,4.4.1.11 ko:K01739,ko:K01761 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017 R00654,R00999,R01288,R02508,R03217,R03260,R04770,R04944,R04945,R04946 RC00020,RC00056,RC00069,RC00196,RC00348,RC00420,RC01209,RC01210,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000 - - - Cys_Met_Meta_PP k141_8630_6 1117647.M5M_10780 4.99e-79 238.0 COG1522@1|root,COG1522@2|Bacteria,1MXVU@1224|Proteobacteria,1T01J@1236|Gammaproteobacteria 1236|Gammaproteobacteria K helix_turn_helix ASNC type - - - - - - - - - - - - AsnC_trans_reg,HTH_24 k141_8630_7 1453501.JELR01000001_gene2097 1.33e-310 862.0 COG2866@1|root,COG2866@2|Bacteria,1N9W9@1224|Proteobacteria,1RPC7@1236|Gammaproteobacteria,4646W@72275|Alteromonadaceae 1236|Gammaproteobacteria E Zinc carboxypeptidase - - - - - - - - - - - - Peptidase_M14 k141_8630_8 1042377.AFPJ01000009_gene325 1.23e-127 380.0 COG1757@1|root,COG1757@2|Bacteria,1MVDF@1224|Proteobacteria,1RS40@1236|Gammaproteobacteria,464WZ@72275|Alteromonadaceae 1236|Gammaproteobacteria C Na H antiporter nhaC - - ko:K03315 - - - - ko00000,ko02000 2.A.35 - - Na_H_antiporter k141_399_1 218284.CCDN010000001_gene277 5.7e-123 361.0 COG4565@1|root,COG4565@2|Bacteria,1TS2Z@1239|Firmicutes,4HCJ5@91061|Bacilli,1ZANG@1386|Bacillus 91061|Bacilli KT transcriptional regulatory protein - - - - - - - - - - - - HTH_11 k141_13430_1 1227739.Hsw_4079 8.97e-68 226.0 COG0635@1|root,COG0635@2|Bacteria,4NFEE@976|Bacteroidetes,47JXR@768503|Cytophagia 976|Bacteroidetes H Involved in the biosynthesis of porphyrin-containing compound hemN - - - - - - - - - - - HemN_C,Radical_SAM k141_24058_1 1294265.JCM21738_3376 6.92e-147 421.0 COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,4HA1G@91061|Bacilli,1ZASC@1386|Bacillus 91061|Bacilli G COG0366 Glycosidases treC - 3.2.1.93 ko:K01226 ko00500,map00500 - R00837,R06113 RC00049 ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,DUF3459,Malt_amylase_C k141_25283_2 218284.CCDN010000001_gene930 2.59e-21 92.4 COG1459@1|root,COG1459@2|Bacteria,1U00C@1239|Firmicutes,4HGUA@91061|Bacilli,1ZCQK@1386|Bacillus 91061|Bacilli NU COG1459 Type II secretory pathway, component PulF comGB - - ko:K02244 - M00429 - - ko00000,ko00002,ko02044 3.A.14.1 - - T2SSF k141_15776_1 1042377.AFPJ01000008_gene2002 4.24e-99 295.0 COG0119@1|root,COG0119@2|Bacteria,1MUMX@1224|Proteobacteria,1RMUX@1236|Gammaproteobacteria,469DW@72275|Alteromonadaceae 1236|Gammaproteobacteria E HMGL-like - - 4.1.3.4 ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 M00036,M00088 R01360,R08090 RC00502,RC00503,RC01118,RC01946 ko00000,ko00001,ko00002,ko01000 - - - HMGL-like k141_29949_1 218284.CCDN010000008_gene4152 5.11e-45 148.0 COG0759@1|root,COG0759@2|Bacteria,1VEIG@1239|Firmicutes,4HPA3@91061|Bacilli,1ZHVV@1386|Bacillus 91061|Bacilli S Could be involved in insertion of integral membrane proteins into the membrane ytjA - - ko:K08998 - - - - ko00000 - - - Haemolytic k141_6369_1 1453501.JELR01000002_gene449 3.85e-117 358.0 COG1629@1|root,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria,465TV@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_20447_1 866895.HBHAL_4154 1.65e-12 67.0 COG2223@1|root,COG2223@2|Bacteria,1TPR9@1239|Firmicutes,4HB93@91061|Bacilli,3NFX3@45667|Halobacillus 91061|Bacilli P Major Facilitator Superfamily oxlT - - ko:K08177 - - - - ko00000,ko02000 2.A.1.11 - - MFS_1 k141_20447_2 866895.HBHAL_2630 2.42e-92 276.0 COG2345@1|root,COG2345@2|Bacteria,1V23D@1239|Firmicutes,4HGV8@91061|Bacilli 91061|Bacilli K Sigma-54 dependent transcriptional regulator - - - - - - - - - - - - - k141_14537_1 637911.AM305_07148 3.58e-13 67.0 COG0640@1|root,COG0640@2|Bacteria,1QE8U@1224|Proteobacteria,1TASJ@1236|Gammaproteobacteria,1YAE5@135625|Pasteurellales 135625|Pasteurellales K transcriptional - - - ko:K03892 - - - - ko00000,ko03000 - - - HTH_20 k141_14537_2 1123368.AUIS01000014_gene2288 2.29e-48 157.0 COG0394@1|root,COG0394@2|Bacteria,1MWYQ@1224|Proteobacteria,1S2YD@1236|Gammaproteobacteria,2NCUY@225057|Acidithiobacillales 225057|Acidithiobacillales T low molecular weight - - 1.20.4.1 ko:K03741 - - - - ko00000,ko01000 - - - LMWPc k141_10984_1 1145276.T479_08740 2.02e-72 232.0 COG1820@1|root,COG1820@2|Bacteria,1TPFK@1239|Firmicutes,4HC6C@91061|Bacilli,3IXG7@400634|Lysinibacillus 91061|Bacilli G Belongs to the metallo-dependent hydrolases superfamily. NagA family nagA - 3.5.1.25 ko:K01443 ko00520,ko01130,map00520,map01130 - R02059 RC00166,RC00300 ko00000,ko00001,ko01000 - - - Amidohydro_1 k141_8631_1 926550.CLDAP_10520 1.12e-32 130.0 COG0210@1|root,COG0210@2|Bacteria,2G86J@200795|Chloroflexi 200795|Chloroflexi L UvrD-like helicase C-terminal domain - - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C k141_1443_1 946483.Cenrod_2199 6.75e-07 56.2 COG1199@1|root,COG1199@2|Bacteria,1MVCU@1224|Proteobacteria,2VH0V@28216|Betaproteobacteria,4AB1Y@80864|Comamonadaceae 28216|Betaproteobacteria KL SMART helicase c2 dinG - 3.6.4.12 ko:K03722 - - - - ko00000,ko01000,ko03400 - - - DEAD,DEAD_2,Helicase_C_2 k141_3942_1 1382359.JIAL01000001_gene1741 8.95e-52 181.0 COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria,3Y5CQ@57723|Acidobacteria,2JKVX@204432|Acidobacteriia 204432|Acidobacteriia C Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S - - 1.5.5.1 ko:K00311 - - - - ko00000,ko01000 - - - ETF_QO k141_26631_1 1279017.AQYJ01000028_gene2314 6.64e-94 296.0 COG0471@1|root,COG3273@1|root,COG0471@2|Bacteria,COG3273@2|Bacteria,1MU0K@1224|Proteobacteria,1RMI1@1236|Gammaproteobacteria,465YV@72275|Alteromonadaceae 1236|Gammaproteobacteria P Sodium:sulfate symporter transmembrane region - - - - - - - - - - - - CitMHS,Na_sulph_symp,TrkA_C k141_9788_1 78245.Xaut_1570 3.06e-66 209.0 COG0346@1|root,COG0346@2|Bacteria,1R8DA@1224|Proteobacteria,2TTKJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria E glyoxalase bleomycin resistance protein dioxygenase - - 5.1.3.33 ko:K20431 ko00525,ko01130,map00525,map01130 M00815 R11079 RC01519 ko00000,ko00001,ko00002,ko01000 - - - Glyoxalase,Glyoxalase_4 k141_37086_1 218284.CCDN010000006_gene3670 2.45e-100 304.0 COG0793@1|root,COG0793@2|Bacteria,1TPBI@1239|Firmicutes,4HAKE@91061|Bacilli,1ZBDE@1386|Bacillus 91061|Bacilli M Belongs to the peptidase S41A family ctpB GO:0003674,GO:0003824,GO:0004175,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008233,GO:0009653,GO:0009987,GO:0016787,GO:0019538,GO:0023052,GO:0030154,GO:0030288,GO:0030313,GO:0030435,GO:0031975,GO:0032502,GO:0033218,GO:0034641,GO:0042277,GO:0042597,GO:0042802,GO:0042803,GO:0043170,GO:0043603,GO:0043900,GO:0043902,GO:0043934,GO:0044237,GO:0044238,GO:0044464,GO:0046983,GO:0048518,GO:0048522,GO:0048646,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070011,GO:0071704,GO:0140096,GO:1900190,GO:1900192,GO:1901564 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - PDZ,PDZ_2,PG_binding_1,Peptidase_S41 k141_21718_1 420246.GTNG_1007 4.41e-53 183.0 COG0044@1|root,COG0044@2|Bacteria,1TPQM@1239|Firmicutes,4HA90@91061|Bacilli,1WE5C@129337|Geobacillus 91061|Bacilli F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily pyrC GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 k141_31239_2 936589.HMPREF1521_0898 4.06e-05 48.9 COG0210@1|root,COG0210@2|Bacteria,1TRTJ@1239|Firmicutes,4H2NT@909932|Negativicutes 909932|Negativicutes L DNA helicase - - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - RNase_T,UvrD-helicase,UvrD_C,UvrD_C_2 k141_33580_1 43989.cce_2208 3.8e-57 184.0 COG1853@1|root,COG1853@2|Bacteria,1G4QZ@1117|Cyanobacteria,3KGJX@43988|Cyanothece 1117|Cyanobacteria S Flavin reductase like domain - - - - - - - - - - - - Flavin_Reduct k141_10985_1 1408303.JNJJ01000071_gene3130 2.16e-42 145.0 COG0789@1|root,COG0789@2|Bacteria,1TS6Z@1239|Firmicutes,4HCVW@91061|Bacilli,1ZBMT@1386|Bacillus 91061|Bacilli K transcriptional mta - - - - - - - - - - - MerR_1,TipAS k141_10985_2 555088.DealDRAFT_0166 9.98e-55 176.0 COG2304@1|root,COG2304@2|Bacteria,1TRPP@1239|Firmicutes,249HV@186801|Clostridia 186801|Clostridia S Psort location Cytoplasmic, score - - - - - - - - - - - - VWA k141_13433_1 1280681.AUJZ01000026_gene392 8.54e-41 150.0 COG0584@1|root,COG5492@1|root,COG0584@2|Bacteria,COG5492@2|Bacteria,1VH9A@1239|Firmicutes,24JIU@186801|Clostridia,4BXPQ@830|Butyrivibrio 186801|Clostridia N glycerophosphoryl diester phosphodiesterase - - - - - - - - - - - - Big_2,GDPD k141_18424_4 1116375.VEJY3_14300 1.5e-146 415.0 COG0546@1|root,COG0546@2|Bacteria,1RDDY@1224|Proteobacteria,1S3QD@1236|Gammaproteobacteria,1XUKY@135623|Vibrionales 135623|Vibrionales G Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress gph GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008967,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 - R01334 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 k141_18424_5 223926.28807816 1.01e-169 474.0 COG0566@1|root,COG0566@2|Bacteria,1MWCM@1224|Proteobacteria,1RN2F@1236|Gammaproteobacteria,1XU81@135623|Vibrionales 135623|Vibrionales J Specifically methylates the ribose of guanosine 2251 in 23S rRNA rlmB GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 ko:K03218 - - - - ko00000,ko01000,ko03009 - - - SpoU_methylase,SpoU_sub_bind k141_18424_6 1116375.VEJY3_14310 0.0 1484.0 COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,1RMQE@1236|Gammaproteobacteria,1XTHJ@135623|Vibrionales 135623|Vibrionales J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs rnr GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008997,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 - ko:K12573 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03016,ko03019 - - - HTH_12,OB_RNB,RNB,S1 k141_18424_7 1116375.VEJY3_14315 3.41e-91 267.0 COG1959@1|root,COG1959@2|Bacteria,1N05H@1224|Proteobacteria,1S8SJ@1236|Gammaproteobacteria,1XX3V@135623|Vibrionales 135623|Vibrionales K Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress. May require iron for activity nsrR GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - ko:K13771 ko05132,map05132 - - - ko00000,ko00001,ko03000 - - - Rrf2 k141_18424_8 1116375.VEJY3_14320 1.23e-258 712.0 COG1017@1|root,COG1018@1|root,COG1017@2|Bacteria,COG1018@2|Bacteria,1MV41@1224|Proteobacteria,1RMPJ@1236|Gammaproteobacteria,1XU5S@135623|Vibrionales 135623|Vibrionales C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress hmp GO:0000166,GO:0001505,GO:0003674,GO:0003824,GO:0004155,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0008150,GO:0008152,GO:0008941,GO:0009056,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016705,GO:0016708,GO:0017144,GO:0019725,GO:0030003,GO:0033554,GO:0034641,GO:0036094,GO:0042133,GO:0042135,GO:0042592,GO:0042737,GO:0043167,GO:0043168,GO:0044237,GO:0044248,GO:0044270,GO:0044464,GO:0046209,GO:0046210,GO:0046916,GO:0048037,GO:0048878,GO:0050660,GO:0050662,GO:0050801,GO:0050896,GO:0051213,GO:0051409,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0071500,GO:0071949,GO:0072593,GO:0097159,GO:0098771,GO:1901265,GO:1901363,GO:2001057 1.14.12.17 ko:K05916 ko05132,map05132 - - - ko00000,ko00001,ko01000 - - - FAD_binding_6,Globin,NAD_binding_1 k141_18424_9 674977.VMC_31800 5.81e-117 338.0 COG0790@1|root,COG0790@2|Bacteria,1RE9M@1224|Proteobacteria,1RPR8@1236|Gammaproteobacteria,1XT10@135623|Vibrionales 135623|Vibrionales N flagellar protein motX motX GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K21217 ko02040,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - Sel1 k141_18424_10 223926.28807822 5.97e-80 248.0 COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,1RNEW@1236|Gammaproteobacteria,1XU7G@135623|Vibrionales 135623|Vibrionales F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP purA GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 - - - Adenylsucc_synt k141_10118_1 1123377.AUIV01000006_gene1563 4.41e-61 212.0 COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,1RN2W@1236|Gammaproteobacteria,1X465@135614|Xanthomonadales 135614|Xanthomonadales E Glutamate synthase gltB - 1.4.1.13,1.4.1.14 ko:K00265 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - GATase_2,GXGXG,Glu_syn_central,Glu_synthase k141_23211_1 1117647.M5M_16805 4.59e-193 557.0 COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,1RNIT@1236|Gammaproteobacteria,1J4P5@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria G Belongs to the GPI family pgi - 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGI k141_23211_2 1122194.AUHU01000003_gene2166 1.52e-84 266.0 COG3934@1|root,COG3934@2|Bacteria,1N159@1224|Proteobacteria,1RRC1@1236|Gammaproteobacteria,467ZH@72275|Alteromonadaceae 1236|Gammaproteobacteria G Cellulase (glycosyl hydrolase family 5) - - 3.2.1.78 ko:K19355 ko00051,map00051 - R01332 RC00467 ko00000,ko00001,ko01000 - - - Cellulase k141_35012_1 1042377.AFPJ01000004_gene357 2.5e-132 379.0 COG2519@1|root,COG2519@2|Bacteria,1QU0A@1224|Proteobacteria,1S03F@1236|Gammaproteobacteria,46DA6@72275|Alteromonadaceae 1236|Gammaproteobacteria J Spermine/spermidine synthase domain - - - - - - - - - - - - Spermine_synth k141_35012_2 1094980.Mpsy_0084 7.04e-247 711.0 COG0531@1|root,arCOG00009@2157|Archaea 2157|Archaea E amino acid - GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - ko:K03294 - - - - ko00000 2.A.3.2 - - AA_permease_2 k141_6502_1 218284.CCDN010000001_gene751 5.43e-71 215.0 COG0818@1|root,COG0818@2|Bacteria,1VEGR@1239|Firmicutes,4HNKN@91061|Bacilli,1ZHW0@1386|Bacillus 91061|Bacilli M Diacylglycerol kinase dgkA - 2.7.1.107,2.7.1.66 ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 - R02240,R05626 RC00002,RC00017 ko00000,ko00001,ko01000 - - iSB619.SA_RS07900 DAGK_prokar k141_6502_2 218284.CCDN010000001_gene750 2.95e-67 206.0 COG0319@1|root,COG0319@2|Bacteria,1V6BU@1239|Firmicutes,4HIIE@91061|Bacilli,1ZG7I@1386|Bacillus 91061|Bacilli S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ybeY - - ko:K07042 - - - - ko00000,ko03009 - - - UPF0054 k141_8910_1 338966.Ppro_0642 3.46e-68 229.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,42NDJ@68525|delta/epsilon subdivisions,2WJSH@28221|Deltaproteobacteria,43TQ2@69541|Desulfuromonadales 28221|Deltaproteobacteria H Belongs to the PEP-utilizing enzyme family ppdK - 2.7.9.1 ko:K01006 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 M00169,M00171,M00172,M00173 R00206 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - PEP-utilizers,PEP-utilizers_C,PPDK_N k141_37277_2 1116375.VEJY3_17271 1.26e-243 670.0 COG1063@1|root,COG1063@2|Bacteria,1MV9A@1224|Proteobacteria,1RWRJ@1236|Gammaproteobacteria,1XWEE@135623|Vibrionales 135623|Vibrionales E Alcohol dehydrogenase GroES-like domain - - - - - - - - - - - - ADH_N,ADH_zinc_N k141_37277_3 1116375.VEJY3_17266 6.47e-119 340.0 COG1917@1|root,COG1917@2|Bacteria,1N0BS@1224|Proteobacteria,1SBE0@1236|Gammaproteobacteria,1XWAF@135623|Vibrionales 135623|Vibrionales S ChrR Cupin-like domain - - - - - - - - - - - - Cupin_7 k141_37277_4 1116375.VEJY3_17261 5.49e-161 453.0 COG1028@1|root,COG1028@2|Bacteria,1NVZG@1224|Proteobacteria,1RWRI@1236|Gammaproteobacteria,1XVRE@135623|Vibrionales 135623|Vibrionales IQ KR domain - - - - - - - - - - - - adh_short_C2 k141_37277_5 1116375.VEJY3_17256 3.14e-202 564.0 COG2207@1|root,COG2207@2|Bacteria,1RG3C@1224|Proteobacteria,1S50G@1236|Gammaproteobacteria,1XWCA@135623|Vibrionales 135623|Vibrionales K Arabinose-binding domain of AraC transcription regulator, N-term - - - - - - - - - - - - Arabinose_bd,HTH_18 k141_37277_6 1116375.VEJY3_17241 0.0 994.0 COG2723@1|root,COG2723@2|Bacteria,1MWG6@1224|Proteobacteria,1RMM2@1236|Gammaproteobacteria,1XSV6@135623|Vibrionales 135623|Vibrionales G Belongs to the glycosyl hydrolase 1 family bglA - 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 - R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 - GT1 - Glyco_hydro_1 k141_37277_7 1116375.VEJY3_17231 8.05e-74 229.0 COG1609@1|root,COG1609@2|Bacteria,1N4ND@1224|Proteobacteria,1RNR5@1236|Gammaproteobacteria,1XVKJ@135623|Vibrionales 135623|Vibrionales K Transcriptional regulator, LacI family - - - ko:K02529,ko:K03487 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 k141_12580_1 1116375.VEJY3_04470 1.03e-87 270.0 COG3014@1|root,COG3014@2|Bacteria,1PD4S@1224|Proteobacteria,1RQ8Y@1236|Gammaproteobacteria,1XUG4@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria - - - ko:K09859 - - - - ko00000 - - - - k141_12580_2 1116375.VEJY3_04475 1.05e-82 245.0 COG5633@1|root,COG5633@2|Bacteria,1N0YQ@1224|Proteobacteria,1S20S@1236|Gammaproteobacteria,1XXI4@135623|Vibrionales 135623|Vibrionales S periplasmic lipoprotein - - - - - - - - - - - - DUF1425 k141_12580_3 1116375.VEJY3_04480 8.47e-130 369.0 COG3417@1|root,COG3417@2|Bacteria,1RA6V@1224|Proteobacteria,1S30E@1236|Gammaproteobacteria,1XUJ6@135623|Vibrionales 135623|Vibrionales M Collagen-binding surface adhesin SpaP (Antigen I II family) lpoB - - ko:K07337 - - - - ko00000 - - - LpoB k141_12580_4 223926.28805955 2.15e-171 483.0 COG0510@1|root,COG0510@2|Bacteria,1MURU@1224|Proteobacteria,1RNUN@1236|Gammaproteobacteria,1XTBI@135623|Vibrionales 135623|Vibrionales M choline kinase involved in LPS biosynthesis thiK - - - - - - - - - - - APH,Choline_kinase k141_12580_5 1116375.VEJY3_04490 2.6e-127 362.0 COG3150@1|root,COG3150@2|Bacteria,1NV1Y@1224|Proteobacteria,1RPQX@1236|Gammaproteobacteria,1XUBH@135623|Vibrionales 135623|Vibrionales S Belongs to the UPF0227 family ycfP - - ko:K07000 - - - - ko00000 - - - UPF0227 k141_12580_6 1116375.VEJY3_04495 8.4e-297 811.0 COG1252@1|root,COG1252@2|Bacteria,1MX96@1224|Proteobacteria,1RM9I@1236|Gammaproteobacteria,1XTJK@135623|Vibrionales 135623|Vibrionales C COG1252 NADH dehydrogenase, FAD-containing subunit ndh - 1.6.99.3 ko:K03885 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - Pyr_redox_2 k141_12580_7 1219076.N646_1189 1.17e-127 374.0 COG2056@1|root,COG2056@2|Bacteria,1N8U2@1224|Proteobacteria,1RRW5@1236|Gammaproteobacteria,1XSSP@135623|Vibrionales 135623|Vibrionales S Na+-H+ antiporter family - - - ko:K07084 - - - - ko00000,ko02000 2.A.8.1.12 - - Na_H_antiport_2,Na_H_antiporter k141_7581_1 1449048.JQKU01000005_gene4600 1.2e-61 216.0 COG2114@1|root,COG2197@1|root,COG3903@1|root,COG2114@2|Bacteria,COG2197@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,233DM@1762|Mycobacteriaceae 201174|Actinobacteria K involved in signal transduction (via phosphorylation) involved in transcriptional regulatory mechanism and in the regulation of secondary metabolites catalytic activity ATP a protein ADP a phosphoprotein - - - - - - - - - - - - GerE,Guanylate_cyc,NB-ARC k141_19556_1 1231057.AMGD01000006_gene2692 3.77e-35 128.0 COG0604@1|root,COG0604@2|Bacteria,1TQ0M@1239|Firmicutes,4HA8M@91061|Bacilli,26FIU@186818|Planococcaceae 91061|Bacilli C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - - - - - - - - - - - ADH_N,ADH_zinc_N_2 k141_1631_1 1227360.C176_14502 1.74e-57 189.0 COG0592@1|root,COG0592@2|Bacteria,1U7RA@1239|Firmicutes,4HARM@91061|Bacilli,26H1D@186818|Planococcaceae 91061|Bacilli L DNA polymerase III beta subunit - - 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3 k141_1631_2 218284.CCDN010000001_gene453 4.23e-92 275.0 COG2207@1|root,COG2207@2|Bacteria,1UZ0B@1239|Firmicutes,4HBRQ@91061|Bacilli,1ZE9J@1386|Bacillus 91061|Bacilli K AraC family transcriptional regulator - - - - - - - - - - - - HTH_18,HTH_AraC k141_1631_3 1461580.CCAS010000012_gene1574 1.33e-96 285.0 COG0546@1|root,COG0546@2|Bacteria,1V421@1239|Firmicutes,4HHYH@91061|Bacilli,1ZQ23@1386|Bacillus 91061|Bacilli S Haloacid dehalogenase-like hydrolase - - - - - - - - - - - - HAD_2 k141_26882_1 1149133.ppKF707_2071 1.77e-18 86.3 COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,1RMSR@1236|Gammaproteobacteria,1YENE@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria M Belongs to the peptidase S41A family ctpA - 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - PDZ_2,Peptidase_S41 k141_10119_1 1294265.JCM21738_4936 1.25e-41 151.0 COG0058@1|root,COG0297@1|root,COG0058@2|Bacteria,COG0297@2|Bacteria,1TQAJ@1239|Firmicutes,4H9XI@91061|Bacilli,1ZCRF@1386|Bacillus 91061|Bacilli G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties glgP GO:0000272,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005976,GO:0005977,GO:0005980,GO:0006073,GO:0006091,GO:0006112,GO:0008144,GO:0008150,GO:0008152,GO:0008184,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0015980,GO:0016052,GO:0016740,GO:0016757,GO:0016758,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901575 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 - R02111 - ko00000,ko00001,ko01000 - GT35 iYO844.BSU30940 Phosphorylase k141_10119_2 1294265.JCM21738_4936 1.42e-68 229.0 COG0058@1|root,COG0297@1|root,COG0058@2|Bacteria,COG0297@2|Bacteria,1TQAJ@1239|Firmicutes,4H9XI@91061|Bacilli,1ZCRF@1386|Bacillus 91061|Bacilli G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties glgP GO:0000272,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005976,GO:0005977,GO:0005980,GO:0006073,GO:0006091,GO:0006112,GO:0008144,GO:0008150,GO:0008152,GO:0008184,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0015980,GO:0016052,GO:0016740,GO:0016757,GO:0016758,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901575 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 - R02111 - ko00000,ko00001,ko01000 - GT35 iYO844.BSU30940 Phosphorylase k141_24241_1 1004785.AMBLS11_01225 2.2e-31 124.0 COG0845@1|root,COG5569@1|root,COG0845@2|Bacteria,COG5569@2|Bacteria,1MVAS@1224|Proteobacteria,1RPBZ@1236|Gammaproteobacteria,464X2@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family cusB - - ko:K07798 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.6.1.4,8.A.1 - - CusF_Ec,HlyD_D23,HlyD_D4 k141_24241_2 1056820.KB900654_gene3117 2.94e-44 167.0 COG1538@1|root,COG1538@2|Bacteria,1NW1T@1224|Proteobacteria,1RPGN@1236|Gammaproteobacteria 1236|Gammaproteobacteria MU outer membrane efflux protein - - - - - - - - - - - - OEP k141_24241_5 1121935.AQXX01000124_gene77 7.35e-93 276.0 2DKHM@1|root,309GY@2|Bacteria,1RFJ6@1224|Proteobacteria,1S4EG@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_24241_6 1453501.JELR01000002_gene1170 4.52e-54 171.0 COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,1S8YR@1236|Gammaproteobacteria,467YU@72275|Alteromonadaceae 1236|Gammaproteobacteria O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter groS GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - ko:K04078 - - - - ko00000,ko03029,ko03110 - - - Cpn10 k141_24241_7 1453501.JELR01000002_gene1169 2.76e-234 655.0 COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,1RSH1@1236|Gammaproteobacteria,465PI@72275|Alteromonadaceae 1236|Gammaproteobacteria O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions - - - ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 - - - Cpn60_TCP1 k141_25566_1 218284.CCDN010000005_gene3182 3.89e-51 168.0 28I6D@1|root,2Z89E@2|Bacteria,1TQNW@1239|Firmicutes,4HCGQ@91061|Bacilli,1ZAQM@1386|Bacillus 91061|Bacilli S EcsC protein family ecsC - - - - - - - - - - - EcsC k141_15936_1 218284.CCDN010000002_gene2932 6.27e-49 155.0 2BX0I@1|root,335P2@2|Bacteria,1VGI6@1239|Firmicutes,4HQNB@91061|Bacilli,1ZHXH@1386|Bacillus 91061|Bacilli - - yfhS - - - - - - - - - - - - k141_15936_2 218284.CCDN010000002_gene2931 7.99e-57 186.0 COG1194@1|root,COG1194@2|Bacteria,1TPUT@1239|Firmicutes,4H9UM@91061|Bacilli,1ZD5Y@1386|Bacillus 91061|Bacilli L A G-specific mutY - - ko:K03575 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD,NUDIX_4 k141_37278_1 218284.CCDN010000001_gene1544 1.5e-32 123.0 COG1686@1|root,COG1686@2|Bacteria,1TQN0@1239|Firmicutes,4HBD4@91061|Bacilli,1ZAS6@1386|Bacillus 91061|Bacilli M Belongs to the peptidase S11 family dacA GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0009002,GO:0016787,GO:0017171,GO:0019538,GO:0030312,GO:0043170,GO:0044238,GO:0044464,GO:0070008,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.16.4 ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - PBP5_C,Peptidase_S11 k141_20673_4 1279017.AQYJ01000024_gene1031 8.53e-83 251.0 COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,1S41D@1236|Gammaproteobacteria,467B9@72275|Alteromonadaceae 1236|Gammaproteobacteria D COG0424 Nucleotide-binding protein implicated in inhibition of septum formation yhdE GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030145,GO:0036218,GO:0036221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0047429 - ko:K06287 - - - - ko00000 - - - Maf k141_20673_6 1279017.AQYJ01000024_gene1033 1.51e-25 105.0 COG3164@1|root,COG3164@2|Bacteria,1MXWF@1224|Proteobacteria,1RNUK@1236|Gammaproteobacteria,464CY@72275|Alteromonadaceae 1236|Gammaproteobacteria S membrane yhdP GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0042597,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - - - - - - - - - - AsmA_2,DUF3971 k141_13738_1 1279017.AQYJ01000028_gene2420 3.03e-94 280.0 COG3038@1|root,COG3038@2|Bacteria,1MZ7X@1224|Proteobacteria,1S3RF@1236|Gammaproteobacteria,467A7@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG3038 Cytochrome B561 yceJ GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K12262 - - - - ko00000 - - - Ni_hydr_CYTB k141_13738_4 1279017.AQYJ01000028_gene2424 2.76e-60 189.0 COG5622@1|root,COG5622@2|Bacteria,1N6XP@1224|Proteobacteria,1SCD9@1236|Gammaproteobacteria,4691R@72275|Alteromonadaceae 1236|Gammaproteobacteria N Protein required for attachment to host cells - - - - - - - - - - - - Host_attach k141_13738_5 1279017.AQYJ01000028_gene2425 2.97e-07 50.1 COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,1S607@1236|Gammaproteobacteria,468FQ@72275|Alteromonadaceae 1236|Gammaproteobacteria O Belongs to the small heat shock protein (HSP20) family - - - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 k141_10120_1 1294265.JCM21738_1129 3.36e-23 96.7 COG3227@1|root,COG3227@2|Bacteria,1TP08@1239|Firmicutes,4H9S6@91061|Bacilli,1ZCEP@1386|Bacillus 91061|Bacilli E Peptidase M4 - - 3.4.24.28 ko:K01400 - - - - ko00000,ko01000,ko01002 - - - FTP,PepSY,Peptidase_M4,Peptidase_M4_C,Peptidase_S8 k141_24242_1 1210884.HG799465_gene11386 1.23e-120 354.0 COG4948@1|root,COG4948@2|Bacteria,2IY85@203682|Planctomycetes 203682|Planctomycetes M Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - 4.2.1.171 ko:K21624 ko00330,map00330 - R11625 - ko00000,ko00001,ko01000 - - - MR_MLE_C,MR_MLE_N k141_7582_1 218284.CCDN010000001_gene1912 3.28e-134 399.0 COG1298@1|root,COG1298@2|Bacteria,1TQBM@1239|Firmicutes,4H9XU@91061|Bacilli,1ZBID@1386|Bacillus 91061|Bacilli N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin flhA - - ko:K02400 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 - - FHIPEP k141_27706_1 324057.Pjdr2_2896 3.14e-83 253.0 COG0500@1|root,COG2226@2|Bacteria,1UYID@1239|Firmicutes,4HAJE@91061|Bacilli,26UBK@186822|Paenibacillaceae 91061|Bacilli Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_25 k141_11275_2 1453501.JELR01000001_gene3011 2.26e-303 831.0 COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,1RMSF@1236|Gammaproteobacteria,464AT@72275|Alteromonadaceae 1236|Gammaproteobacteria S GTPase that plays an essential role in the late steps of ribosome biogenesis der GO:0000027,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022607,GO:0022613,GO:0022618,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032794,GO:0034622,GO:0035639,GO:0036094,GO:0042254,GO:0042255,GO:0042273,GO:0043021,GO:0043022,GO:0043023,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0097159,GO:0097216,GO:0097367,GO:1901265,GO:1901363 - ko:K03977 - - - - ko00000,ko03009 - - - KH_dom-like,MMR_HSR1 k141_11275_3 1453501.JELR01000001_gene3010 5.73e-294 809.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,4641R@72275|Alteromonadaceae 1236|Gammaproteobacteria C belongs to the aldehyde dehydrogenase family - - 1.2.1.16,1.2.1.20,1.2.1.79 ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 M00027 R00713,R00714,R02401 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_11275_4 1279017.AQYJ01000023_gene3147 1.03e-128 369.0 COG1720@1|root,COG1720@2|Bacteria,1MUF0@1224|Proteobacteria,1RPCX@1236|Gammaproteobacteria,466V7@72275|Alteromonadaceae 1236|Gammaproteobacteria S Uncharacterised protein family UPF0066 yaeB GO:0000049,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016426,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0089715,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363 - - - - - - - - - - UPF0066 k141_11275_5 1122194.AUHU01000005_gene932 2.42e-73 239.0 COG4232@1|root,COG4233@1|root,COG4232@2|Bacteria,COG4233@2|Bacteria,1MU8W@1224|Proteobacteria,1RPF7@1236|Gammaproteobacteria,46550@72275|Alteromonadaceae 1236|Gammaproteobacteria CO Thiol disulfide interchange protein - - 1.8.1.8 ko:K04084 - - - - ko00000,ko01000,ko03110 5.A.1.1 - - DsbC,DsbD,Thioredoxin_7 k141_36064_1 1294265.JCM21738_300 4.05e-28 107.0 COG1317@1|root,COG1317@2|Bacteria,1VEUV@1239|Firmicutes,4HGNK@91061|Bacilli,1ZQRU@1386|Bacillus 91061|Bacilli NU Flagellar assembly protein FliH fliH - - ko:K02411 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - FliH k141_36064_2 1294265.JCM21738_301 1.03e-122 360.0 COG1157@1|root,COG1157@2|Bacteria,1TP0R@1239|Firmicutes,4HAUY@91061|Bacilli,1ZBXU@1386|Bacillus 91061|Bacilli NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase fliI - 3.6.3.14 ko:K02412 ko02040,map02040 - - - ko00000,ko00001,ko01000,ko02035,ko02044 3.A.6.2,3.A.6.3 - - ATP-synt_ab,ATP-synt_ab_N k141_10121_1 218284.CCDN010000004_gene3036 8.66e-173 486.0 COG2834@1|root,COG2834@2|Bacteria,1TSRE@1239|Firmicutes,4HBCH@91061|Bacilli,1ZBE6@1386|Bacillus 91061|Bacilli M COG2834 Outer membrane lipoprotein-sorting protein ydcC - - - - - - - - - - - DUF4367 k141_2840_1 42565.FP66_07510 1.6e-50 172.0 COG0477@1|root,COG0477@2|Bacteria,1MWUR@1224|Proteobacteria,1T1TP@1236|Gammaproteobacteria,1XK1J@135619|Oceanospirillales 135619|Oceanospirillales EGP Major Facilitator Superfamily - - - ko:K08169 - - - - ko00000,ko02000 2.A.1.3.17 - - MFS_1 k141_2840_2 42565.FP66_07515 5.97e-28 103.0 2CGNP@1|root,32S4A@2|Bacteria,1N1J7@1224|Proteobacteria,1SAPA@1236|Gammaproteobacteria,1XMNJ@135619|Oceanospirillales 135619|Oceanospirillales S Psort location Cytoplasmic, score 8.96 - - - - - - - - - - - - - k141_26884_1 218284.CCDN010000002_gene2903 6.11e-246 681.0 COG2270@1|root,COG2270@2|Bacteria,1TRTH@1239|Firmicutes,4H9VB@91061|Bacilli,1ZDX4@1386|Bacillus 91061|Bacilli S COG2270 Permeases of the major facilitator superfamily yxiO - - ko:K06902 ko04138,map04138 - - - ko00000,ko00001,ko02000,ko04131 2.A.1.24,9.A.15.1 - - ATG22 k141_6503_1 1294265.JCM21738_172 2.5e-124 363.0 COG0369@1|root,COG1151@2|Bacteria,1TP8X@1239|Firmicutes,4HAK7@91061|Bacilli,1ZCAC@1386|Bacillus 91061|Bacilli C Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O hcp - 1.7.99.1 ko:K05601 ko00910,map00910 - R00143 RC02797 ko00000,ko00001,ko01000 - - - Prismane k141_24244_1 1347087.CBYO010000022_gene3269 0.000253 46.6 2EEKG@1|root,338EC@2|Bacteria,1VJUG@1239|Firmicutes,4HPPQ@91061|Bacilli 91061|Bacilli S Domain of unknown function (DUF4181) - - - - - - - - - - - - DUF4181 k141_37280_1 1453501.JELR01000002_gene586 1.89e-67 205.0 COG0832@1|root,COG0832@2|Bacteria,1RGW0@1224|Proteobacteria,1S8UP@1236|Gammaproteobacteria,467XS@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the urease beta subunit family ureB GO:0003674,GO:0003824,GO:0006807,GO:0008150,GO:0008152,GO:0009039,GO:0016787,GO:0016810,GO:0016811 3.5.1.5 ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 - R00131 RC02798,RC02806 ko00000,ko00001,ko01000 - - iECH74115_1262.ECH74115_1322,iECO103_1326.ECO103_3798,iECO111_1330.ECO111_1228,iECSP_1301.ECSP_1250,iECs_1301.ECs1323,iUMNK88_1353.UMNK88_1200,iZ_1308.Z1144,iZ_1308.Z1583 Urease_beta k141_37280_2 1208321.D104_12405 2.24e-54 171.0 COG0831@1|root,COG0831@2|Bacteria,1RGXE@1224|Proteobacteria,1S65Y@1236|Gammaproteobacteria,1XK3W@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the urease gamma subunit family ureA - 3.5.1.5 ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 - R00131 RC02798,RC02806 ko00000,ko00001,ko01000 - - - Urease_gamma k141_37280_3 1453501.JELR01000002_gene588 1.98e-18 82.8 COG0829@1|root,COG0829@2|Bacteria,1RABD@1224|Proteobacteria,1RSB2@1236|Gammaproteobacteria,466PK@72275|Alteromonadaceae 1236|Gammaproteobacteria O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter ureD - - ko:K03190 - - - - ko00000 - - - UreD k141_19559_2 638302.HMPREF0908_1007 0.00011 45.1 COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes 1239|Firmicutes O Belongs to the thioredoxin family trxA GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - ko:K03671 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - Thioredoxin k141_8911_2 1279017.AQYJ01000028_gene2302 1.41e-115 337.0 COG1451@1|root,COG1451@2|Bacteria,1MXZU@1224|Proteobacteria,1S9E4@1236|Gammaproteobacteria,467T2@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function DUF45 - - - ko:K07043 - - - - ko00000 - - - DUF45 k141_13773_1 1453501.JELR01000001_gene2508 2.96e-200 578.0 28IUR@1|root,2Z8TE@2|Bacteria,1NW7C@1224|Proteobacteria,1RP4W@1236|Gammaproteobacteria,465G0@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_13773_2 1042377.AFPJ01000016_gene157 2.95e-11 61.6 COG0529@1|root,COG0529@2|Bacteria,1MX0D@1224|Proteobacteria,1RNWT@1236|Gammaproteobacteria,465TQ@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the synthesis of activated sulfate cysC - 2.7.1.25,2.7.7.4 ko:K00860,ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176,M00596 R00509,R00529,R04928,R04929 RC00002,RC00078,RC02809,RC02889 ko00000,ko00001,ko00002,ko01000 - - - APS_kinase,ATP-sulfurylase,PUA_2 k141_36076_2 1453501.JELR01000001_gene2115 2.86e-133 389.0 COG0668@1|root,COG0668@2|Bacteria,1N596@1224|Proteobacteria,1RQZP@1236|Gammaproteobacteria,465C6@72275|Alteromonadaceae 1236|Gammaproteobacteria M Mechanosensitive ion channel - - - - - - - - - - - - MS_channel,TM_helix k141_36076_3 1279017.AQYJ01000025_gene609 7.7e-163 464.0 COG2355@1|root,COG2355@2|Bacteria,1MWEW@1224|Proteobacteria,1RYET@1236|Gammaproteobacteria,469YE@72275|Alteromonadaceae 1236|Gammaproteobacteria E Membrane dipeptidase (Peptidase family M19) - - - - - - - - - - - - Peptidase_M19 k141_25598_1 218284.CCDN010000001_gene1521 4.19e-91 271.0 COG1346@1|root,COG1346@2|Bacteria,1TRGN@1239|Firmicutes,4HF0M@91061|Bacilli,1ZFQ6@1386|Bacillus 91061|Bacilli M effector of murein hydrolase - - - - - - - - - - - - LrgB k141_23234_1 218284.CCDN010000008_gene4198 2.78e-201 575.0 COG1523@1|root,COG1523@2|Bacteria,1TP3M@1239|Firmicutes,4HBP5@91061|Bacilli,1ZC85@1386|Bacillus 91061|Bacilli G Belongs to the glycosyl hydrolase 13 family amyX - 3.2.1.41 ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 - R02111 - ko00000,ko00001,ko01000 - CBM48,GH13 - Alpha-amylase,CBM_48 k141_19585_1 1231057.AMGD01000005_gene2789 1.23e-85 264.0 COG0531@1|root,COG0531@2|Bacteria,1TVM4@1239|Firmicutes,4HP9X@91061|Bacilli,26H2U@186818|Planococcaceae 91061|Bacilli E Amino acid permease - - - - - - - - - - - - AA_permease_2 k141_11312_1 218284.CCDN010000001_gene1362 4.92e-40 147.0 COG1193@1|root,COG1193@2|Bacteria,1TQWB@1239|Firmicutes,4HAHW@91061|Bacilli,1ZC6C@1386|Bacillus 91061|Bacilli L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity mutS1 - - ko:K07456 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_V k141_12605_1 218284.CCDN010000002_gene2106 2.35e-185 521.0 COG1071@1|root,COG1071@2|Bacteria,1TQDG@1239|Firmicutes,4H9PR@91061|Bacilli,1ZARF@1386|Bacillus 91061|Bacilli C Dehydrogenase E1 component - - 1.2.4.1 ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh k141_6517_2 1294265.JCM21738_106 7.44e-72 221.0 28J08@1|root,2Z8XG@2|Bacteria,1V177@1239|Firmicutes,4HCWC@91061|Bacilli,1ZCRV@1386|Bacillus 91061|Bacilli - - yphF - - - - - - - - - - - DUF3939 k141_35031_1 866895.HBHAL_1703 7.33e-33 124.0 2B68X@1|root,31Z68@2|Bacteria,1V93N@1239|Firmicutes,4HIJ8@91061|Bacilli,3NF8W@45667|Halobacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_20710_1 1453501.JELR01000002_gene1505 2.68e-62 198.0 COG2962@1|root,COG2962@2|Bacteria,1MX5G@1224|Proteobacteria,1RMAC@1236|Gammaproteobacteria,465R2@72275|Alteromonadaceae 1236|Gammaproteobacteria S RarD protein rarD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016021,GO:0031224,GO:0044425,GO:0044464,GO:0071944 - ko:K05786 - - - - ko00000,ko02000 2.A.7.7 - - EamA k141_23235_1 314278.NB231_12259 1.63e-69 234.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1WWNH@135613|Chromatiales 135613|Chromatiales V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K18138 ko01501,ko01503,map01501,map01503 M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2 - - ACR_tran k141_15948_1 406124.ACPC01000019_gene2869 7.65e-66 206.0 COG1121@1|root,COG1121@2|Bacteria,1TQJ3@1239|Firmicutes,4HA2W@91061|Bacilli,1ZC67@1386|Bacillus 91061|Bacilli P 'COG1121 ABC-type Mn Zn transport systems, ATPase component' mntB - 3.6.3.35 ko:K02074,ko:K09820,ko:K11710,ko:K19973 ko02010,map02010 M00243,M00244,M00319,M00792 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.15,3.A.1.15.15 - iYO844.BSU30760 ABC_tran k141_15948_2 1462527.CCDM010000001_gene1809 3.24e-14 71.2 COG0803@1|root,COG0803@2|Bacteria,1TRKU@1239|Firmicutes,4HAKT@91061|Bacilli,23K1U@182709|Oceanobacillus 91061|Bacilli P Zinc-uptake complex component A periplasmic troA - - ko:K11707 ko02010,map02010 M00319 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15 - - ZnuA k141_14718_1 1453501.JELR01000002_gene1410 6.13e-26 103.0 COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,1S64Q@1236|Gammaproteobacteria,467V3@72275|Alteromonadaceae 1236|Gammaproteobacteria S Competence protein gntX GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0015976,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 - - - - - - - - - - Pribosyltran k141_673_2 1280001.BAOA01000024_gene5223 1.82e-57 178.0 COG0633@1|root,COG0633@2|Bacteria,1NCXF@1224|Proteobacteria,1SDEV@1236|Gammaproteobacteria,1XYDB@135623|Vibrionales 135623|Vibrionales C ferredoxin - - - - - - - - - - - - Fer2 k141_673_3 223926.28808021 1.88e-160 450.0 COG0543@1|root,COG0543@2|Bacteria,1MV72@1224|Proteobacteria,1RPH5@1236|Gammaproteobacteria,1XVAC@135623|Vibrionales 135623|Vibrionales C COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases fre - 1.16.1.3,1.5.1.41 ko:K05368 ko00740,ko00860,ko01100,map00740,map00860,map01100 - R00097,R05705 RC00126,RC00220 ko00000,ko00001,ko01000 - - - FAD_binding_6,NAD_binding_1 k141_6681_1 1308866.J416_03081 1.67e-17 77.4 2EM3I@1|root,33ET1@2|Bacteria,1VI7I@1239|Firmicutes,4HRBY@91061|Bacilli,470ZR@74385|Gracilibacillus 91061|Bacilli S Phage holin family Hol44, in holin superfamily V - - - - - - - - - - - - Phage_holin_5_2 k141_37437_1 1279017.AQYJ01000022_gene2670 8.72e-43 151.0 COG0810@1|root,COG0810@2|Bacteria,1RKRA@1224|Proteobacteria,1S83X@1236|Gammaproteobacteria,46CRY@72275|Alteromonadaceae 1236|Gammaproteobacteria M TonB C terminal - - - ko:K03646 - - - - ko00000,ko02000 2.C.1.2 - - TonB_2 k141_27115_1 1294265.JCM21738_2569 5.2e-199 558.0 COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,4HARF@91061|Bacilli,1ZC4E@1386|Bacillus 91061|Bacilli E COG0747 ABC-type dipeptide transport system, periplasmic component appA - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 k141_23414_1 1243664.CAVL020000041_gene3958 8.37e-72 224.0 COG1077@1|root,COG1077@2|Bacteria,1TP51@1239|Firmicutes,4HA4S@91061|Bacilli,1ZC87@1386|Bacillus 91061|Bacilli D Rod shape-determining protein mbl - - ko:K03569 - - - - ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 - - MreB_Mbl k141_12774_1 42565.FP66_09275 2.64e-81 253.0 COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,1RM7I@1236|Gammaproteobacteria,1XIIV@135619|Oceanospirillales 135619|Oceanospirillales C Belongs to the heme-copper respiratory oxidase family ccoN - 1.9.3.1 ko:K00404 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - COX1 k141_12774_2 42565.FP66_09280 8.38e-12 62.8 COG2993@1|root,COG2993@2|Bacteria,1MXEY@1224|Proteobacteria,1RPU6@1236|Gammaproteobacteria,1XH6P@135619|Oceanospirillales 135619|Oceanospirillales C COG2993 Cbb3-type cytochrome oxidase, cytochrome c subunit ccoO - - ko:K00405 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002 3.D.4.3 - - FixO k141_35239_1 925775.XVE_0499 5.66e-15 77.4 COG0258@1|root,COG0258@2|Bacteria,1RAAR@1224|Proteobacteria,1RN1S@1236|Gammaproteobacteria,1X448@135614|Xanthomonadales 135614|Xanthomonadales L Exodeoxyribonuclease IX exo - - - - - - - - - - - 5_3_exonuc,5_3_exonuc_N k141_35239_2 1279017.AQYJ01000029_gene3342 9.28e-171 488.0 COG0111@1|root,COG0111@2|Bacteria,1N5TD@1224|Proteobacteria,1RMFW@1236|Gammaproteobacteria,465GC@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate pdxB GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0033711,GO:0034641,GO:0036001,GO:0036094,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.1.1.290 ko:K03473 ko00750,ko01100,map00750,map01100 M00124 R04210 RC00084 ko00000,ko00001,ko00002,ko01000 - - iZ_1308.Z3582 2-Hacid_dh,2-Hacid_dh_C,DUF3410 k141_35239_3 1279017.AQYJ01000029_gene3343 1.33e-211 592.0 COG3199@1|root,COG3199@2|Bacteria,1MY3J@1224|Proteobacteria,1RP9X@1236|Gammaproteobacteria,464PX@72275|Alteromonadaceae 1236|Gammaproteobacteria S Diacylglycerol kinase catalytic domain - - - - - - - - - - - - NAD_kinase k141_35239_4 511062.GU3_12140 9.6e-08 55.8 COG1092@1|root,COG1092@2|Bacteria,1PUHQ@1224|Proteobacteria,1RN8N@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Belongs to the methyltransferase superfamily - - 2.1.1.191 ko:K06969 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_SAM k141_4247_1 1453501.JELR01000002_gene952 7.89e-72 244.0 COG0643@1|root,COG0745@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,4650G@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0643 Chemotaxis protein histidine kinase and related kinases chpA - - ko:K02487,ko:K06596 ko02020,ko02025,map02020,map02025 M00507 - - ko00000,ko00001,ko00002,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg k141_9082_1 218284.CCDN010000002_gene2830 4.69e-72 220.0 COG3153@1|root,COG3153@2|Bacteria,1V6SP@1239|Firmicutes,4HJZU@91061|Bacilli,1ZHIK@1386|Bacillus 91061|Bacilli S Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_9 k141_9082_2 218284.CCDN010000002_gene2831 3.42e-48 154.0 COG1918@1|root,COG1918@2|Bacteria,1VFH1@1239|Firmicutes,4HMT6@91061|Bacilli,1ZJ8W@1386|Bacillus 91061|Bacilli P FeoA - - - ko:K04758 - - - - ko00000,ko02000 - - - FeoA k141_5580_1 1279017.AQYJ01000026_gene275 3.28e-227 658.0 COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,464QT@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0642 Signal transduction histidine kinase barA GO:0000155,GO:0000160,GO:0000302,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009636,GO:0009927,GO:0009987,GO:0010033,GO:0010035,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0035556,GO:0036211,GO:0042221,GO:0042493,GO:0042542,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046677,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0070887,GO:0071310,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901700 2.7.13.3 ko:K07678 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 M00475 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - DUF2222,HAMP,HATPase_c,HisKA,Hpt,Response_reg k141_20804_1 1294265.JCM21738_675 1.27e-108 322.0 COG0065@1|root,COG0065@2|Bacteria,1TPE5@1239|Firmicutes,4HAWA@91061|Bacilli,1ZCF1@1386|Bacillus 91061|Bacilli E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate leuC - 4.2.1.33,4.2.1.35 ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170 RC00497,RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS10700 Aconitase k141_11519_1 1294265.JCM21738_92 1.5e-148 419.0 COG5581@1|root,COG5581@2|Bacteria,1V31U@1239|Firmicutes,4HGFE@91061|Bacilli,1ZCCG@1386|Bacillus 91061|Bacilli M Flagellar protein YcgR ypfA - - - - - - - - - - - PilZ,YcgR_2 k141_27141_1 333138.LQ50_21815 2.79e-50 174.0 29H5Q@1|root,30439@2|Bacteria,1V63Q@1239|Firmicutes,4HHR2@91061|Bacilli,1ZE9T@1386|Bacillus 91061|Bacilli S Nuclease-related domain - - - - - - - - - - - - NERD k141_14005_1 218284.CCDN010000002_gene2787 5.53e-249 691.0 COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,4H9SZ@91061|Bacilli,1ZAX7@1386|Bacillus 91061|Bacilli E Sodium alanine symporter agcS - - ko:K03310 - - - - ko00000 2.A.25 - - Na_Ala_symp k141_24483_2 223926.28807984 2.15e-51 162.0 COG3776@1|root,COG3776@2|Bacteria,1NGTV@1224|Proteobacteria,1SGYB@1236|Gammaproteobacteria,1XYBG@135623|Vibrionales 135623|Vibrionales S membrane - - - ko:K08993 - - - - ko00000 - - - DUF1145 k141_24483_3 1280001.BAOA01000112_gene4644 7.67e-43 140.0 2E9BS@1|root,32TZH@2|Bacteria,1PCX5@1224|Proteobacteria,1SY2T@1236|Gammaproteobacteria,1XZ0N@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF2492) - - - - - - - - - - - - DUF2492 k141_24483_4 1116375.VEJY3_14955 8.6e-128 365.0 COG3714@1|root,COG3714@2|Bacteria,1N6QN@1224|Proteobacteria,1SCQK@1236|Gammaproteobacteria,1XW1H@135623|Vibrionales 135623|Vibrionales S YhhN family - - - - - - - - - - - - YhhN k141_24483_5 223926.28807990 5.37e-79 235.0 2E6DG@1|root,33113@2|Bacteria,1QJRJ@1224|Proteobacteria,1THSU@1236|Gammaproteobacteria,1XXF8@135623|Vibrionales 135623|Vibrionales - - VP2964 - - - - - - - - - - - DUF4145 k141_24483_6 223926.28807991 1.24e-71 215.0 293IY@1|root,2ZR0Z@2|Bacteria,1RFZ4@1224|Proteobacteria,1SF6E@1236|Gammaproteobacteria,1XXSZ@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF2500) VP2965 - - - - - - - - - - - DUF2500 k141_24483_7 1116375.VEJY3_14975 1.26e-224 621.0 COG3274@1|root,COG3274@2|Bacteria,1MUJ6@1224|Proteobacteria,1S09B@1236|Gammaproteobacteria,1XT5S@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria - - - - - - - - - - - - Acyl_transf_3 k141_24483_8 1116375.VEJY3_14980 4.34e-280 767.0 COG0477@1|root,COG2814@2|Bacteria,1MV8D@1224|Proteobacteria,1RNF0@1236|Gammaproteobacteria,1XTRW@135623|Vibrionales 135623|Vibrionales EGP of the major facilitator superfamily - - - - - - - - - - - - MFS_1 k141_24483_9 1116375.VEJY3_14985 1.86e-106 308.0 COG2453@1|root,COG2453@2|Bacteria,1N0H0@1224|Proteobacteria,1S9JV@1236|Gammaproteobacteria,1XWW6@135623|Vibrionales 135623|Vibrionales T phosphatase - - - - - - - - - - - - CDKN3,DSPc k141_24483_10 1116375.VEJY3_14990 1.2e-236 651.0 COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,1RMBM@1236|Gammaproteobacteria,1XV8J@135623|Vibrionales 135623|Vibrionales C Belongs to the glyceraldehyde-3-phosphate dehydrogenase family gap - 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N k141_24483_11 1219076.N646_2066 4.28e-73 219.0 COG0640@1|root,COG0640@2|Bacteria,1MZT1@1224|Proteobacteria,1SAI5@1236|Gammaproteobacteria,1XXDF@135623|Vibrionales 135623|Vibrionales K transcriptional arsR - - ko:K03892 - - - - ko00000,ko03000 - - - HTH_5 k141_24483_12 1116375.VEJY3_15005 3.63e-124 356.0 COG1280@1|root,COG1280@2|Bacteria,1MXAI@1224|Proteobacteria,1RPWN@1236|Gammaproteobacteria,1XT72@135623|Vibrionales 135623|Vibrionales E threonine efflux protein rhtB GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015175,GO:0015179,GO:0015318,GO:0015711,GO:0015804,GO:0015807,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0042968,GO:0042970,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - ko:K05834 - - - - ko00000,ko02000 2.A.76.1.1 - - LysE k141_24483_13 1116375.VEJY3_15010 1.18e-227 628.0 COG2267@1|root,COG2267@2|Bacteria,1MWDA@1224|Proteobacteria,1RRJP@1236|Gammaproteobacteria,1XTME@135623|Vibrionales 135623|Vibrionales I Lysophospholipase pldB - 3.1.1.5 ko:K01048 ko00564,map00564 - - - ko00000,ko00001,ko01000 - - - Hydrolase_4 k141_24483_14 1116375.VEJY3_15015 2.01e-180 504.0 COG0561@1|root,COG0561@2|Bacteria,1MV02@1224|Proteobacteria,1RP1D@1236|Gammaproteobacteria,1XTVR@135623|Vibrionales 135623|Vibrionales S hydrolases of the HAD superfamily yigL - - - - - - - - - - - Hydrolase_3 k141_24483_15 223926.28808002 8.11e-107 308.0 COG2947@1|root,COG2947@2|Bacteria,1RHRU@1224|Proteobacteria,1S68X@1236|Gammaproteobacteria,1XW0F@135623|Vibrionales 135623|Vibrionales S EVE domain - - - - - - - - - - - - EVE k141_24483_16 1116375.VEJY3_15025 2.07e-133 392.0 COG3650@1|root,COG3650@2|Bacteria,1RIIM@1224|Proteobacteria,1S8NS@1236|Gammaproteobacteria,1XSAK@135623|Vibrionales 135623|Vibrionales S response to hydrogen peroxide VP2977 - - ko:K08985 - - - - ko00000 - - - - k141_18690_3 1231057.AMGD01000028_gene1938 2.05e-14 71.6 COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,4HAD5@91061|Bacilli,26DK5@186818|Planococcaceae 91061|Bacilli E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases gltD - 1.4.1.13,1.4.1.14 ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - iSB619.SA_RS02450 Fer4_20,Pyr_redox_2 k141_14872_1 1042377.AFPJ01000036_gene1196 5.07e-99 290.0 COG0778@1|root,COG0778@2|Bacteria,1PKUV@1224|Proteobacteria,1RNQG@1236|Gammaproteobacteria,4678D@72275|Alteromonadaceae 1236|Gammaproteobacteria C nitroreductase ydjA GO:0000166,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0010181,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - - - - - - - - - - Nitroreductase k141_36212_1 1453501.JELR01000001_gene2567 1.09e-183 548.0 COG4913@1|root,COG4913@2|Bacteria,1N16Z@1224|Proteobacteria,1RYVF@1236|Gammaproteobacteria,465ZJ@72275|Alteromonadaceae 1236|Gammaproteobacteria S Putative exonuclease SbcCD, C subunit - - - - - - - - - - - - AAA_29,SbcCD_C k141_25811_1 1453501.JELR01000005_gene1573 1.58e-142 416.0 COG1538@1|root,COG1538@2|Bacteria,1MUHM@1224|Proteobacteria,1RNNS@1236|Gammaproteobacteria,469JV@72275|Alteromonadaceae 1236|Gammaproteobacteria MU Outer membrane efflux protein - - - - - - - - - - - - OEP k141_829_1 1453501.JELR01000001_gene2248 5.57e-92 288.0 COG2871@1|root,COG3182@1|root,COG2871@2|Bacteria,COG3182@2|Bacteria,1QTUV@1224|Proteobacteria,1RNTI@1236|Gammaproteobacteria,464VZ@72275|Alteromonadaceae 1236|Gammaproteobacteria C 2Fe-2S iron-sulfur cluster binding domain - - - - - - - - - - - - FAD_binding_6,Fer2,NAD_binding_1,PepSY_TM k141_12791_1 1051632.TPY_1074 2.27e-89 278.0 COG1884@1|root,COG1884@2|Bacteria,1TQAD@1239|Firmicutes,24BDK@186801|Clostridia 186801|Clostridia I PFAM Methylmalonyl-CoA mutase - - 5.4.99.2 ko:K01848 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00375,M00376,M00741 R00833 RC00395 ko00000,ko00001,ko00002,ko01000 - - - MM_CoA_mutase k141_35278_1 218284.CCDN010000001_gene1399 3.65e-109 330.0 COG1966@1|root,COG1966@2|Bacteria,1TQN8@1239|Firmicutes,4H9SU@91061|Bacilli,1ZC6K@1386|Bacillus 91061|Bacilli T Carbon starvation protein cstA GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007154,GO:0008150,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031667,GO:0031668,GO:0031669,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:0071944 - ko:K06200 - - - - ko00000 - - - CstA,CstA_5TM k141_14006_1 1453501.JELR01000001_gene1921 6.7e-88 262.0 COG0745@1|root,COG0745@2|Bacteria,1MVCB@1224|Proteobacteria,1RMW7@1236|Gammaproteobacteria,466IP@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain cpxR - - ko:K07662 ko01503,ko02020,map01503,map02020 M00447,M00727,M00728 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C k141_22076_1 1294265.JCM21738_360 3.79e-183 512.0 COG0130@1|root,COG0130@2|Bacteria,1TP9Y@1239|Firmicutes,4HA9X@91061|Bacilli,1ZBKE@1386|Bacillus 91061|Bacilli J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs truB GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 ko:K03177,ko:K03483 - - - - ko00000,ko01000,ko03000,ko03016 - - iSB619.SA_RS06305 TruB-C_2,TruB_C_2,TruB_N k141_6710_1 218284.CCDN010000001_gene519 7.83e-133 386.0 COG0538@1|root,COG0538@2|Bacteria,1UHPE@1239|Firmicutes,4H9US@91061|Bacilli,1ZBWV@1386|Bacillus 91061|Bacilli C isocitrate icd - 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh k141_27142_1 1120953.AUBH01000003_gene1978 0.000379 45.8 COG0457@1|root,COG0457@2|Bacteria,1REXI@1224|Proteobacteria,1SYRM@1236|Gammaproteobacteria,46CY6@72275|Alteromonadaceae 1236|Gammaproteobacteria S Putative 2OG-Fe(II) oxygenase - - - - - - - - - - - - 2OG-FeII_Oxy_5,TPR_16,TPR_19,TPR_8 k141_27142_2 314225.ELI_01455 2.25e-10 65.5 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,2TTJG@28211|Alphaproteobacteria,2JZUI@204457|Sphingomonadales 204457|Sphingomonadales P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec k141_2991_2 406124.ACPC01000005_gene3572 1.21e-65 203.0 COG3832@1|root,COG3832@2|Bacteria,1UA2K@1239|Firmicutes,4IKBZ@91061|Bacilli,1ZGDN@1386|Bacillus 91061|Bacilli J glyoxalase III activity - - - - - - - - - - - - Polyketide_cyc2 k141_2991_3 665959.HMPREF1013_00068 3.26e-79 243.0 COG0640@1|root,COG0640@2|Bacteria,1VJ43@1239|Firmicutes,4HQM5@91061|Bacilli,1ZMJE@1386|Bacillus 91061|Bacilli K Activator of Hsp90 ATPase homolog 1-like protein - - - - - - - - - - - - AHSA1,HTH_20 k141_35279_2 1294265.JCM21738_1234 3.81e-13 67.4 COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,4HA59@91061|Bacilli,1ZB8X@1386|Bacillus 91061|Bacilli I 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain hbd - 1.1.1.157 ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 - R01976,R05576,R06941 RC00029,RC00117 ko00000,ko00001,ko01000 - - - 3HCDH,3HCDH_N k141_27887_1 218284.CCDN010000001_gene988 3.74e-190 568.0 COG1404@1|root,COG4412@1|root,COG1404@2|Bacteria,COG4412@2|Bacteria,1TPUY@1239|Firmicutes,4HBDE@91061|Bacilli,1ZDEQ@1386|Bacillus 91061|Bacilli O COG1404 Subtilisin-like serine proteases bpr GO:0005575,GO:0005576 - ko:K13276 - - - - ko00000,ko01000,ko01002,ko03110 - - - CarbopepD_reg_2,CarboxypepD_reg,Inhibitor_I9,Peptidase_M6,Peptidase_S8 k141_14007_1 218284.CCDN010000001_gene1141 9.98e-72 240.0 COG0847@1|root,COG1199@1|root,COG0847@2|Bacteria,COG1199@2|Bacteria,1TQHQ@1239|Firmicutes,4HB2Y@91061|Bacilli,1ZAWI@1386|Bacillus 91061|Bacilli L helicase involved in DNA repair and perhaps also replication dinG - 3.6.4.12 ko:K03722 - - - - ko00000,ko01000,ko03400 - - - DEAD,Helicase_C_2,RNase_T,ResIII k141_7751_2 218284.CCDN010000001_gene63 2.1e-110 319.0 COG2065@1|root,COG2065@2|Bacteria,1V3GV@1239|Firmicutes,4HGYE@91061|Bacilli,1ZB3P@1386|Bacillus 91061|Bacilli F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant pyrR GO:0003674,GO:0003700,GO:0006139,GO:0006220,GO:0006221,GO:0006355,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0031323,GO:0031326,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0072527,GO:0072528,GO:0080090,GO:0090407,GO:0140110,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.4.2.9 ko:K02825 ko00240,ko01100,map00240,map01100 - R00966 RC00063 ko00000,ko00001,ko01000,ko03000 - - - Pribosyltran k141_29186_1 218284.CCDN010000001_gene116 2.27e-47 152.0 2ED1C@1|root,336YB@2|Bacteria,1VJ46@1239|Firmicutes,4HPWX@91061|Bacilli,1ZJ6S@1386|Bacillus 91061|Bacilli S YlbE-like protein ylbE - - - - - - - - - - - YlbE k141_29186_2 218284.CCDN010000001_gene117 3.55e-88 259.0 2DV4S@1|root,32UYM@2|Bacteria,1VA7R@1239|Firmicutes,4HMUX@91061|Bacilli,1ZI1G@1386|Bacillus 91061|Bacilli S Putative coat protein ylbD - - - - - - - - - - - YlbD_coat k141_29186_3 935836.JAEL01000011_gene5218 1.86e-26 102.0 COG2050@1|root,COG2050@2|Bacteria,1VN0K@1239|Firmicutes,4HM66@91061|Bacilli,1ZHD4@1386|Bacillus 91061|Bacilli Q protein, possibly involved in aromatic compounds catabolism - - - ko:K02614 ko00360,map00360 - R09840 RC00004,RC00014 ko00000,ko00001,ko01000 - - - 4HBT k141_6711_1 218284.CCDN010000002_gene2696 1.94e-42 149.0 COG0124@1|root,COG0124@2|Bacteria,1TP3D@1239|Firmicutes,4HAWF@91061|Bacilli,1ZDID@1386|Bacillus 91061|Bacilli J histidyl-tRNA synthetase - - 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_His k141_34026_1 1042377.AFPJ01000019_gene2530 6.78e-14 74.7 COG3047@1|root,COG3047@2|Bacteria 2|Bacteria - - ompW - - ko:K07275 - - - - ko00000 - - - OmpW k141_18693_1 218284.CCDN010000002_gene2849 4.77e-38 135.0 COG0697@1|root,COG0697@2|Bacteria,1TRKE@1239|Firmicutes,4HF69@91061|Bacilli,1ZQ3B@1386|Bacillus 91061|Bacilli EG EamA-like transporter family - - - - - - - - - - - - EamA k141_35280_1 218284.CCDN010000001_gene1644 1.16e-125 363.0 COG0730@1|root,COG0730@2|Bacteria,1TPMA@1239|Firmicutes,4HCYJ@91061|Bacilli,1ZAPI@1386|Bacillus 91061|Bacilli S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE k141_10367_1 1294265.JCM21738_104 1.69e-137 395.0 COG0240@1|root,COG0240@2|Bacteria,1TQ5P@1239|Firmicutes,4HAXW@91061|Bacilli,1ZCHQ@1386|Bacillus 91061|Bacilli I Glycerol-3-phosphate dehydrogenase gpsA GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0047952,GO:0055114 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 - R00842,R00844 RC00029 ko00000,ko00001,ko01000 - - - NAD_Gly3P_dh_C,NAD_Gly3P_dh_N k141_24485_1 1218173.BALCAV_0204785 2.58e-65 203.0 COG1670@1|root,COG1670@2|Bacteria,1V3NE@1239|Firmicutes,4HG1N@91061|Bacilli,1ZEC8@1386|Bacillus 91061|Bacilli J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins ydaF GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008999,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0017198,GO:0018193,GO:0018209,GO:0019538,GO:0030920,GO:0031365,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564,GO:1990189 - ko:K03817 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 k141_24485_2 218284.CCDN010000001_gene1717 5.56e-12 63.2 COG1670@1|root,COG1670@2|Bacteria,1V26J@1239|Firmicutes,4HG0M@91061|Bacilli,1ZE5Z@1386|Bacillus 91061|Bacilli J Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_3 k141_9108_1 1444309.JAQG01000005_gene4329 9.22e-92 296.0 COG1574@1|root,COG1574@2|Bacteria,1TQ6G@1239|Firmicutes,4H9T6@91061|Bacilli 91061|Bacilli S metal-dependent hydrolase with the TIM-barrel fold - - - - - - - - - - - - Amidohydro_3 k141_14874_1 1078085.HMPREF1210_01310 1.25e-11 60.5 2DPF7@1|root,331TZ@2|Bacteria,1VEDX@1239|Firmicutes,4HPQF@91061|Bacilli,26G5U@186818|Planococcaceae 91061|Bacilli S Family of unknown function (DUF5325) - - - - - - - - - - - - DUF5325 k141_5601_1 1280001.BAOA01000051_gene1592 6.54e-77 265.0 COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,1T1X2@1236|Gammaproteobacteria,1XUBS@135623|Vibrionales 135623|Vibrionales Q COG2931, RTX toxins and related Ca2 -binding proteins - - - - - - - - - - - - - k141_5601_2 1280001.BAOA01000051_gene1593 2.44e-135 394.0 2AVT3@1|root,31MKG@2|Bacteria,1QJEW@1224|Proteobacteria,1THE8@1236|Gammaproteobacteria,1XURJ@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - SPOR k141_5601_3 1116375.VEJY3_00225 2.97e-216 598.0 COG1173@1|root,COG1173@2|Bacteria,1MUG0@1224|Proteobacteria,1RN08@1236|Gammaproteobacteria,1XTS5@135623|Vibrionales 135623|Vibrionales P COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components dppC - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1,OppC_N k141_5601_4 223926.28805031 5.81e-219 606.0 COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,1RNJ1@1236|Gammaproteobacteria,1XTA1@135623|Vibrionales 135623|Vibrionales P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components dppB - - ko:K02033 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 k141_5601_5 1116375.VEJY3_00215 0.0 1017.0 COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,1RNES@1236|Gammaproteobacteria,1XTQI@135623|Vibrionales 135623|Vibrionales E COG0747 ABC-type dipeptide transport system, periplasmic component dppA - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 k141_5601_6 1116375.VEJY3_00210 1.61e-223 627.0 COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,1RMEI@1236|Gammaproteobacteria,1XTGQ@135623|Vibrionales 135623|Vibrionales P Belongs to the ABC transporter superfamily dppD - - ko:K02031,ko:K02032 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - ABC_tran,oligo_HPY k141_2992_1 42565.FP66_03835 3.99e-27 109.0 COG0398@1|root,COG1249@1|root,COG0398@2|Bacteria,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RQTU@1236|Gammaproteobacteria,1XHNV@135619|Oceanospirillales 135619|Oceanospirillales C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - - - - - - - - - - Pyr_redox_2,Pyr_redox_dim,SNARE_assoc k141_2992_2 42565.FP66_03835 3.52e-81 260.0 COG0398@1|root,COG1249@1|root,COG0398@2|Bacteria,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RQTU@1236|Gammaproteobacteria,1XHNV@135619|Oceanospirillales 135619|Oceanospirillales C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - - - - - - - - - - Pyr_redox_2,Pyr_redox_dim,SNARE_assoc k141_20827_1 1002809.SSIL_2408 2.91e-207 591.0 COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,4H9VR@91061|Bacilli,26DUZ@186818|Planococcaceae 91061|Bacilli E COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase - - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N k141_18694_1 428127.EUBDOL_00236 1.38e-07 58.9 COG0749@1|root,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,3VNWN@526524|Erysipelotrichia 526524|Erysipelotrichia L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A k141_17301_1 672.VV93_v1c04950 2.61e-104 315.0 COG2378@1|root,COG2378@2|Bacteria,1QYA2@1224|Proteobacteria,1RZAX@1236|Gammaproteobacteria,1XWGX@135623|Vibrionales 135623|Vibrionales K transcriptional regulator - - - - - - - - - - - - WYL k141_7752_1 218284.CCDN010000004_gene3140 2.52e-62 197.0 COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4H9WY@91061|Bacilli,1ZB2E@1386|Bacillus 91061|Bacilli E COG1126 ABC-type polar amino acid transport system, ATPase component tcyC - - ko:K10010 ko02010,map02010 M00234 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3.10,3.A.1.3.14 - iSB619.SA_RS12615 ABC_tran k141_9109_1 1279017.AQYJ01000028_gene2074 2.8e-58 204.0 COG1729@1|root,COG1729@2|Bacteria,1MX82@1224|Proteobacteria,1T32S@1236|Gammaproteobacteria,465Q0@72275|Alteromonadaceae 1236|Gammaproteobacteria O protein conserved in bacteria - - - - - - - - - - - - TPR_16,TPR_6,TPR_8,YfiO k141_22078_1 1283337.B0ZSI2_BPHA1 2.13e-143 420.0 4QASF@10239|Viruses,4QZZT@35237|dsDNA viruses no RNA stage,4QT38@28883|Caudovirales,4QJR7@10662|Myoviridae 10662|Myoviridae S Pfam:Telomere_res - - - - - - - - - - - - - k141_831_1 1294265.JCM21738_5229 4.95e-132 383.0 COG2843@1|root,COG2843@2|Bacteria,1UZW4@1239|Firmicutes,4HB06@91061|Bacilli,1ZCM3@1386|Bacillus 91061|Bacilli M Bacterial capsule synthesis protein PGA_cap capA - - ko:K07282 - - - - ko00000 - - - PGA_cap k141_35282_2 218284.CCDN010000004_gene3084 7.26e-35 126.0 COG0564@1|root,COG0564@2|Bacteria,1TSM6@1239|Firmicutes,4HA7M@91061|Bacilli,1ZDMG@1386|Bacillus 91061|Bacilli J Responsible for synthesis of pseudouridine from uracil rluA GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23,5.4.99.28,5.4.99.29 ko:K06177,ko:K06180 - - - - ko00000,ko01000,ko03009,ko03016 - - - PseudoU_synth_2 k141_24487_1 316274.Haur_3795 6.58e-53 172.0 COG1528@1|root,COG1528@2|Bacteria,2G8JG@200795|Chloroflexi,37728@32061|Chloroflexia 32061|Chloroflexia C Iron-storage protein - - 1.16.3.2 ko:K02217 - - - - ko00000,ko01000 - - - Ferritin k141_27146_1 1340434.AXVA01000028_gene816 3.51e-29 111.0 29WX8@1|root,30IJ9@2|Bacteria,1UJ4S@1239|Firmicutes,4IT1A@91061|Bacilli,1ZCC6@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_1781_1 218284.CCDN010000001_gene218 4.24e-143 416.0 COG0365@1|root,COG0365@2|Bacteria,1TQTI@1239|Firmicutes,4H9PN@91061|Bacilli,1ZCDC@1386|Bacillus 91061|Bacilli I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases ytcI GO:0003674,GO:0003824,GO:0003996,GO:0004321,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0015645,GO:0016053,GO:0016405,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0016874,GO:0016877,GO:0016878,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901576 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 - - - AMP-binding,AMP-binding_C k141_5603_1 1042377.AFPJ01000004_gene347 7.51e-140 437.0 COG1520@1|root,COG2133@1|root,COG1520@2|Bacteria,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,1RNGN@1236|Gammaproteobacteria,465UX@72275|Alteromonadaceae 1236|Gammaproteobacteria G Glucose / Sorbosone dehydrogenase - - - - - - - - - - - - Big_2,CBM26,Cytochrome_CBB3,GSDH,PSCyt3,PSD2,PSD3,PSD4,PSD5 k141_9110_1 240302.BN982_02496 1.71e-95 292.0 COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,4H9VK@91061|Bacilli,3ND3W@45667|Halobacillus 91061|Bacilli G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system rbsA GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0006810,GO:0008144,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015146,GO:0015399,GO:0015405,GO:0015407,GO:0015591,GO:0015608,GO:0015611,GO:0015749,GO:0015750,GO:0015752,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034219,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043211,GO:0043492,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0097159,GO:0097367,GO:1901265,GO:1901363 3.6.3.17 ko:K10441 ko02010,map02010 M00212 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - ABC_tran k141_14008_1 218284.CCDN010000002_gene2050 2.8e-83 252.0 COG3859@1|root,COG3859@2|Bacteria,1V6YE@1239|Firmicutes,4HIJE@91061|Bacilli,1ZCR3@1386|Bacillus 91061|Bacilli S Proton-coupled thiamine transporter YuaJ thiT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K16789 - - - - ko00000,ko02000 2.A.88.3 - - Thia_YuaJ k141_14008_2 218284.CCDN010000002_gene2049 1.4e-43 144.0 29T9S@1|root,30EGR@2|Bacteria,1UCIR@1239|Firmicutes,4IP0W@91061|Bacilli,1ZP7W@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_22079_1 218284.CCDN010000005_gene3236 9.34e-92 278.0 COG2311@1|root,COG2311@2|Bacteria,1TQNS@1239|Firmicutes,4HCR3@91061|Bacilli,1ZBX3@1386|Bacillus 91061|Bacilli P Protein of unknown function (DUF418) - - - ko:K07148 - - - - ko00000 - - - DUF418 k141_22079_2 218284.CCDN010000005_gene3237 3.19e-13 67.8 COG0179@1|root,COG0179@2|Bacteria,1TQDQ@1239|Firmicutes,4HCBR@91061|Bacilli,1ZCHF@1386|Bacillus 91061|Bacilli Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) yisK - - - - - - - - - - - FAA_hydrolase k141_23434_1 1279017.AQYJ01000019_gene1510 8.93e-182 563.0 COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,1RPV3@1236|Gammaproteobacteria,46578@72275|Alteromonadaceae 1236|Gammaproteobacteria NU Tfp pilus assembly protein tip-associated adhesin pilY1 - - ko:K02674 - - - - ko00000,ko02035,ko02044 - - - Neisseria_PilC k141_962_1 1042377.AFPJ01000052_gene1582 4.96e-153 459.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria,4651V@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec k141_27965_1 218284.CCDN010000001_gene774 2.91e-150 427.0 COG1108@1|root,COG1108@2|Bacteria,1TR79@1239|Firmicutes,4HC3C@91061|Bacilli,1ZB0A@1386|Bacillus 91061|Bacilli P COG1108 ABC-type Mn2 Zn2 transport systems, permease components zurM - - ko:K09816 ko02010,map02010 M00242 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15.3,3.A.1.15.5 - - ABC-3 k141_18927_1 1121344.JHZO01000007_gene2114 6.77e-14 73.6 COG1924@1|root,COG1924@2|Bacteria,1TQSD@1239|Firmicutes,2481W@186801|Clostridia,3WI11@541000|Ruminococcaceae 186801|Clostridia I BadF/BadG/BcrA/BcrD ATPase family - - - - - - - - - - - - BcrAD_BadFG,HGD-D k141_23653_1 1515746.HR45_08640 8.85e-113 338.0 COG3203@1|root,COG3203@2|Bacteria,1Q1XX@1224|Proteobacteria,1S7RC@1236|Gammaproteobacteria,2QB23@267890|Shewanellaceae 1236|Gammaproteobacteria M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - - - - - - - - - - Porin_4 k141_23653_2 1515746.HR45_08645 1.13e-53 173.0 COG0226@1|root,COG0226@2|Bacteria,1N7RX@1224|Proteobacteria,1SCQW@1236|Gammaproteobacteria,2QCXV@267890|Shewanellaceae 1236|Gammaproteobacteria P ABC-type phosphate transport system, periplasmic component - - - - - - - - - - - - - k141_963_1 218284.CCDN010000005_gene3207 1.7e-99 301.0 COG3493@1|root,COG3493@2|Bacteria,1TR97@1239|Firmicutes,4HBS8@91061|Bacilli,1ZC12@1386|Bacillus 91061|Bacilli C COG3493 Na citrate symporter mleP - - - - - - - - - - - 2HCT k141_19916_2 1610832.A0A0E3GMP6_9CAUD 4.34e-29 112.0 4QAIU@10239|Viruses,4QPDE@28883|Caudovirales,4QKM7@10699|Siphoviridae 10699|Siphoviridae S HNH endonuclease - - - - - - - - - - - - - k141_29332_1 1397528.Q671_10370 3e-76 231.0 COG1432@1|root,COG1432@2|Bacteria,1MUAE@1224|Proteobacteria,1S47Z@1236|Gammaproteobacteria,1XJQI@135619|Oceanospirillales 135619|Oceanospirillales S nuclease - - - - - - - - - - - - NYN k141_29332_2 637905.SVI_2374 8.99e-42 144.0 COG3148@1|root,COG3148@2|Bacteria,1N0GQ@1224|Proteobacteria,1SAQQ@1236|Gammaproteobacteria,2QCJY@267890|Shewanellaceae 1236|Gammaproteobacteria S PFAM DTW domain containing protein - - - - - - - - - - - - DTW k141_11690_1 406124.ACPC01000007_gene3365 1.14e-139 424.0 COG0577@1|root,COG0577@2|Bacteria,1TRAS@1239|Firmicutes,4HC7R@91061|Bacilli,1ZQH6@1386|Bacillus 91061|Bacilli V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD k141_23654_1 1444310.JANV01000170_gene2414 3.15e-64 204.0 COG1011@1|root,COG1011@2|Bacteria,1TS3W@1239|Firmicutes,4HADE@91061|Bacilli,1ZBN8@1386|Bacillus 91061|Bacilli S HAD-hyrolase-like ysaA - 3.1.3.5,3.8.1.2 ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346,R05287 RC00017,RC00697 ko00000,ko00001,ko01000 - - - HAD_2 k141_27336_1 1116375.VEJY3_20101 1.73e-170 483.0 COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,1RP04@1236|Gammaproteobacteria,1XTGB@135623|Vibrionales 135623|Vibrionales H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans glgC2 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008878,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0070566,GO:0071704,GO:1901576 2.7.7.27 ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase k141_27336_2 1116375.VEJY3_20096 0.0 996.0 COG2759@1|root,COG2759@2|Bacteria,1MUR8@1224|Proteobacteria,1RME6@1236|Gammaproteobacteria,1XUVS@135623|Vibrionales 135623|Vibrionales F Belongs to the formate--tetrahydrofolate ligase family fhs GO:0000096,GO:0000097,GO:0000105,GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006520,GO:0006547,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009108,GO:0009110,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0052803,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.3 ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R00943 RC00026,RC00111 ko00000,ko00001,ko00002,ko01000 - - - FTHFS k141_27336_3 674977.VMC_21850 3.72e-44 154.0 COG0524@1|root,COG0524@2|Bacteria,1MUUC@1224|Proteobacteria,1RMN2@1236|Gammaproteobacteria,1XT8M@135623|Vibrionales 135623|Vibrionales G COG0524 Sugar kinases, ribokinase family - - 2.7.1.73 ko:K00892 ko00230,map00230 - R01131,R01228 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB k141_6894_1 265729.GS18_0202375 1.37e-90 279.0 COG1680@1|root,COG1680@2|Bacteria,1U828@1239|Firmicutes,4HA0Q@91061|Bacilli,1ZBJ0@1386|Bacillus 91061|Bacilli V Belongs to the UPF0214 family ybbE - 3.4.16.4 ko:K21469 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - Beta-lactamase k141_35416_2 1116375.VEJY3_12590 9.58e-136 392.0 COG1015@1|root,COG1015@2|Bacteria,1MVN8@1224|Proteobacteria,1RQ6W@1236|Gammaproteobacteria,1XU6Q@135623|Vibrionales 135623|Vibrionales G Phosphotransfer between the C1 and C5 carbon atoms of pentose deoB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008973,GO:0009987,GO:0016853,GO:0016866,GO:0016868,GO:0034641,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360 5.4.2.7 ko:K01839 ko00030,ko00230,map00030,map00230 - R01057,R02749 RC00408 ko00000,ko00001,ko01000 - - - Metalloenzyme k141_27966_2 1461580.CCAS010000070_gene4071 5.45e-39 141.0 COG1988@1|root,COG1988@2|Bacteria,1TQFC@1239|Firmicutes,4H9PU@91061|Bacilli,1ZFGV@1386|Bacillus 91061|Bacilli S LexA-binding, inner membrane-associated putative hydrolase yfhP - - ko:K07038 - - - - ko00000 - - - YdjM k141_29333_1 1294265.JCM21738_606 3.19e-50 167.0 COG0029@1|root,COG0029@2|Bacteria,1UHSP@1239|Firmicutes,4H9ZZ@91061|Bacilli,1ZBIE@1386|Bacillus 91061|Bacilli H Catalyzes the oxidation of L-aspartate to iminoaspartate nadB - 1.4.3.16 ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 M00115 R00357,R00481 RC00006,RC02566 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C k141_29333_2 1294265.JCM21738_605 3.61e-47 159.0 COG0157@1|root,COG0157@2|Bacteria,1TPQC@1239|Firmicutes,4HB46@91061|Bacilli,1ZBVN@1386|Bacillus 91061|Bacilli H Belongs to the NadC ModD family nadC GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034213,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 2.4.2.19 ko:K00767 ko00760,ko01100,map00760,map01100 M00115 R03348 RC02877 ko00000,ko00001,ko00002,ko01000 - - - QRPTase_C,QRPTase_N k141_34148_1 1042377.AFPJ01000051_gene35 7.36e-92 284.0 28HC9@1|root,2Z7P5@2|Bacteria,1R4BH@1224|Proteobacteria,1RSAN@1236|Gammaproteobacteria,4642U@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_3152_1 1279017.AQYJ01000026_gene248 2.33e-25 99.8 COG3310@1|root,COG3310@2|Bacteria,1RDE0@1224|Proteobacteria,1S3X6@1236|Gammaproteobacteria,467Z8@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria - - - ko:K09941 - - - - ko00000 - - - DUF1415 k141_3152_2 1042377.AFPJ01000016_gene113 5.57e-50 166.0 COG3122@1|root,COG3122@2|Bacteria,1N15V@1224|Proteobacteria,1S5V0@1236|Gammaproteobacteria,467D6@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria yaiL GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K09912 - - - - ko00000 - - iECW_1372.ECW_m0432,iWFL_1372.ECW_m0432 DUF2058 k141_3152_3 1279017.AQYJ01000028_gene2368 0.0 921.0 COG2978@1|root,COG2978@2|Bacteria,1MUJ1@1224|Proteobacteria,1RMAI@1236|Gammaproteobacteria,4642F@72275|Alteromonadaceae 1236|Gammaproteobacteria H Transporter ydaH - - ko:K12942 - - - - ko00000 - - - ABG_transport k141_7936_1 218284.CCDN010000003_gene2970 3.88e-76 234.0 COG0313@1|root,COG0313@2|Bacteria,1TP6U@1239|Firmicutes,4HAH8@91061|Bacilli,1ZBN1@1386|Bacillus 91061|Bacilli H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA rsmI GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 2.1.1.198 ko:K07056 - - - - ko00000,ko01000,ko03009 - - - TP_methylase k141_7936_2 1178540.BA70_10190 5.34e-19 79.3 COG2002@1|root,COG2002@2|Bacteria,1VA3H@1239|Firmicutes,4HKCH@91061|Bacilli,1ZH0F@1386|Bacillus 91061|Bacilli K COG2002 Regulators of stationary sporulation gene expression abrB GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0042802,GO:0043937,GO:0050789,GO:0050793,GO:0065007 - ko:K06284 - - - - ko00000,ko03000 - - - MazE_antitoxin k141_25975_2 218284.CCDN010000001_gene778 1.81e-65 200.0 COG4709@1|root,COG4709@2|Bacteria,1VEVX@1239|Firmicutes,4HP5D@91061|Bacilli,1ZIJI@1386|Bacillus 91061|Bacilli S membrane yqfX - - - - - - - - - - - - k141_18955_1 218284.CCDN010000001_gene761 2.99e-115 340.0 COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,4HB1H@91061|Bacilli,1ZAV8@1386|Bacillus 91061|Bacilli K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth sigA - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 k141_6918_1 997296.PB1_05662 4.83e-118 350.0 COG0519@1|root,COG0519@2|Bacteria,1TPG8@1239|Firmicutes,4HA7Q@91061|Bacilli,1ZB6Z@1386|Bacillus 91061|Bacilli F Catalyzes the synthesis of GMP from XMP guaA GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase,GMP_synt_C,NAD_synthase k141_24649_1 1121439.dsat_0841 4.21e-94 292.0 COG4962@1|root,COG4962@2|Bacteria,1R7EN@1224|Proteobacteria,42NAK@68525|delta/epsilon subdivisions,2WIYX@28221|Deltaproteobacteria,2M8UJ@213115|Desulfovibrionales 28221|Deltaproteobacteria U PFAM Type II secretion system protein E - - - ko:K02283,ko:K03609 - - - - ko00000,ko02035,ko02044,ko03036,ko04812 - - - CbiA,FHA,T2SSE k141_35430_1 218284.CCDN010000001_gene1105 4.07e-162 464.0 COG0699@1|root,COG0699@2|Bacteria,1TPPG@1239|Firmicutes,4HBH1@91061|Bacilli,1ZBNH@1386|Bacillus 91061|Bacilli S ATPase. Has a role at an early stage in the morphogenesis of the spore coat spoIVA GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009653,GO:0009847,GO:0009987,GO:0010927,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022607,GO:0030154,GO:0030203,GO:0030312,GO:0030435,GO:0030554,GO:0031160,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0032989,GO:0034622,GO:0035639,GO:0036094,GO:0042244,GO:0042546,GO:0042601,GO:0042763,GO:0043167,GO:0043168,GO:0043170,GO:0043591,GO:0043595,GO:0043933,GO:0043934,GO:0044085,GO:0044426,GO:0044462,GO:0044464,GO:0045229,GO:0048646,GO:0048856,GO:0048869,GO:0051258,GO:0051259,GO:0065003,GO:0070499,GO:0070590,GO:0070726,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 - ko:K06398 - - - - ko00000 - - - Spore_IV_A k141_14249_2 218284.CCDN010000002_gene2192 1.05e-116 336.0 COG0288@1|root,COG0288@2|Bacteria,1V1EC@1239|Firmicutes,4HFQA@91061|Bacilli,1ZB5T@1386|Bacillus 91061|Bacilli P Reversible hydration of carbon dioxide ytiB - 4.2.1.1 ko:K01673 ko00910,map00910 - R00132,R10092 RC02807 ko00000,ko00001,ko01000 - - - Pro_CA k141_984_1 1453501.JELR01000001_gene2204 1.53e-19 81.6 COG0432@1|root,COG0432@2|Bacteria,1RH13@1224|Proteobacteria,1S3VP@1236|Gammaproteobacteria,467NM@72275|Alteromonadaceae 1236|Gammaproteobacteria S Uncharacterised protein family UPF0047 yjbQ - - - - - - - - - - - UPF0047 k141_984_2 1042377.AFPJ01000009_gene215 4.5e-51 171.0 COG2265@1|root,COG2265@2|Bacteria,1MY45@1224|Proteobacteria,1RN2B@1236|Gammaproteobacteria,4645S@72275|Alteromonadaceae 1236|Gammaproteobacteria J Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA) trmA GO:0000049,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016740,GO:0016741,GO:0019843,GO:0030488,GO:0030696,GO:0030697,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363 2.1.1.35 ko:K00557 - - - - ko00000,ko01000,ko03016 - - - tRNA_U5-meth_tr k141_22328_1 674977.VMC_02100 0.0 1025.0 COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,1RNJI@1236|Gammaproteobacteria,1XUIR@135623|Vibrionales 135623|Vibrionales L COG0210 Superfamily I DNA and RNA helicases uvrD - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C k141_11699_1 1294265.JCM21738_3409 2.53e-129 379.0 COG0497@1|root,COG0497@2|Bacteria,1TP99@1239|Firmicutes,4H9ZR@91061|Bacilli,1ZC8B@1386|Bacillus 91061|Bacilli L May be involved in recombinational repair of damaged DNA recN GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - ko:K03631 - - - - ko00000,ko03400 - - - AAA_23,SMC_N k141_6919_2 1279017.AQYJ01000026_gene6 5.67e-30 108.0 COG3108@1|root,COG3108@2|Bacteria,1NMU6@1224|Proteobacteria 1224|Proteobacteria S Peptidase M15 - - - - - - - - - - - - Peptidase_M15_3 k141_32864_1 42565.FP66_13955 4.22e-83 249.0 COG0517@1|root,COG0517@2|Bacteria,1QV5F@1224|Proteobacteria,1S8MF@1236|Gammaproteobacteria,1XRFN@135619|Oceanospirillales 135619|Oceanospirillales S BON domain - - - - - - - - - - - - BON,CBS k141_27975_3 1042377.AFPJ01000005_gene2477 5.05e-78 238.0 COG3161@1|root,COG3161@2|Bacteria,1N8BF@1224|Proteobacteria,1SDX2@1236|Gammaproteobacteria,46867@72275|Alteromonadaceae 1236|Gammaproteobacteria H Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway ubiC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008813,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.1.3.40 ko:K03181 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R01302 RC00491,RC02148 ko00000,ko00001,ko00002,ko01000 - - iZ_1308.Z5638 Chor_lyase k141_27975_6 1042377.AFPJ01000005_gene2474 8.36e-243 675.0 COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,1RN0F@1236|Gammaproteobacteria,465EB@72275|Alteromonadaceae 1236|Gammaproteobacteria T Signal transduction histidine kinase phoR - 2.7.13.3 ko:K07636 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - DUF3329,HATPase_c,HisKA,PAS,PAS_8 k141_30347_2 1042377.AFPJ01000054_gene1713 1.15e-235 649.0 COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,1RN8G@1236|Gammaproteobacteria,464R4@72275|Alteromonadaceae 1236|Gammaproteobacteria NU COG2805 Tfp pilus assembly protein, pilus retraction ATPase PilT pilT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K02669 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE k141_985_1 76114.ebA3154 8.27e-09 57.8 2C5U9@1|root,30FF7@2|Bacteria,1N2U0@1224|Proteobacteria,2WIIE@28216|Betaproteobacteria,2M01U@206389|Rhodocyclales 206389|Rhodocyclales S Bacterial protein of unknown function (Gcw_chp) - - - - - - - - - - - - Gcw_chp k141_7938_1 768671.ThimaDRAFT_2242 2.48e-45 157.0 COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,1RN44@1236|Gammaproteobacteria,1WWQ1@135613|Chromatiales 135613|Chromatiales H Belongs to the ribF family - - 2.7.1.26,2.7.7.2 ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - FAD_syn,Flavokinase k141_3166_1 1211777.BN77_p10815 2.29e-122 374.0 28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,2TSGX@28211|Alphaproteobacteria,4BCDP@82115|Rhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF3604) - - - - - - - - - - - - DUF3604 k141_18958_1 218284.CCDN010000004_gene3125 4.31e-107 328.0 COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,4HADT@91061|Bacilli,1ZCKV@1386|Bacillus 91061|Bacilli KT Sigma-54 interaction domain - - - - - - - - - - - - HTH_12,HTH_8,PAS,PAS_9,Sigma54_activat k141_14250_2 1279017.AQYJ01000027_gene1766 1.5e-88 263.0 COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,1S3VN@1236|Gammaproteobacteria,466US@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) purE - 5.4.99.18 ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07405 RC01947 ko00000,ko00001,ko00002,ko01000 - - - AIRC k141_9338_1 218284.CCDN010000001_gene1749 1.03e-97 312.0 COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1TPYV@1239|Firmicutes,4HBER@91061|Bacilli,1ZBGN@1386|Bacillus 91061|Bacilli E Methionine synthase metH - 2.1.1.13 ko:K00548 ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230 M00017 R00946,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans k141_986_1 315730.BcerKBAB4_1921 3.59e-87 271.0 COG0154@1|root,COG0154@2|Bacteria,1TRFI@1239|Firmicutes,4HBZA@91061|Bacilli,1ZCZT@1386|Bacillus 91061|Bacilli J COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases gatA1 - 3.5.1.4 ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 - R02540,R03096,R03180,R03909,R05551,R05590 RC00010,RC00100,RC00950,RC01025 ko00000,ko00001,ko01000 - - - Amidase k141_17398_1 218284.CCDN010000001_gene1167 1.99e-246 686.0 COG0843@1|root,COG0843@2|Bacteria,1TPZC@1239|Firmicutes,4HAHT@91061|Bacilli,1ZC76@1386|Bacillus 91061|Bacilli C COG0843 Heme copper-type cytochrome quinol oxidases, subunit 1 cbaA - 1.9.3.1 ko:K02274 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6 - - COX1 k141_19931_2 1279017.AQYJ01000029_gene3930 2.72e-136 393.0 COG5640@1|root,COG5640@2|Bacteria,1R5CZ@1224|Proteobacteria,1S0VW@1236|Gammaproteobacteria,467CF@72275|Alteromonadaceae 1236|Gammaproteobacteria O Trypsin-like serine protease - - - - - - - - - - - - Trypsin k141_23669_1 1116375.VEJY3_03960 4.52e-180 504.0 COG2267@1|root,COG2267@2|Bacteria,1QTAP@1224|Proteobacteria,1S6CX@1236|Gammaproteobacteria,1XSDM@135623|Vibrionales 135623|Vibrionales I hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 k141_23669_2 1116375.VEJY3_03965 0.0 1071.0 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1RMQ4@1236|Gammaproteobacteria,1XVCW@135623|Vibrionales 135623|Vibrionales IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II fadD - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding,AMP-binding_C k141_23669_3 1116375.VEJY3_03970 3.6e-257 707.0 COG0349@1|root,COG0349@2|Bacteria,1MURV@1224|Proteobacteria,1RPBP@1236|Gammaproteobacteria,1XSSU@135623|Vibrionales 135623|Vibrionales J Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides rnd - 3.1.13.5 ko:K03684 - - - - ko00000,ko01000,ko03016 - - - DNA_pol_A_exo1,HRDC k141_23669_4 1046714.AMRX01000006_gene2769 2.07e-83 259.0 COG0463@1|root,COG0463@2|Bacteria,1RBHD@1224|Proteobacteria,1S3K4@1236|Gammaproteobacteria,4686Z@72275|Alteromonadaceae 1236|Gammaproteobacteria M Glycosyl transferase, family 2 - - - - - - - - - - - - Glycos_transf_2 k141_23669_5 1116375.VEJY3_03975 3.45e-52 164.0 COG0851@1|root,COG0851@2|Bacteria,1N6QD@1224|Proteobacteria,1SC8W@1236|Gammaproteobacteria,1XXVX@135623|Vibrionales 135623|Vibrionales D Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell minE - - ko:K03608 - - - - ko00000,ko03036,ko04812 - - - MinE k141_23669_6 223926.28805860 5.85e-185 515.0 COG2894@1|root,COG2894@2|Bacteria,1MUEU@1224|Proteobacteria,1RNJ0@1236|Gammaproteobacteria,1XTBF@135623|Vibrionales 135623|Vibrionales D Belongs to the ParA family minD - - ko:K03609 - - - - ko00000,ko03036,ko04812 - - - AAA_31,CbiA k141_27976_1 1294265.JCM21738_2260 2.47e-127 367.0 COG1597@1|root,COG1597@2|Bacteria,1TUH3@1239|Firmicutes,4IR1U@91061|Bacilli,1ZRQM@1386|Bacillus 91061|Bacilli I Diacylglycerol kinase catalytic domain ytlR - - - - - - - - - - - DAGK_acc,DAGK_cat k141_6921_1 1034347.CAHJ01000054_gene174 7.15e-73 235.0 COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,4HBVK@91061|Bacilli,1ZBPB@1386|Bacillus 91061|Bacilli L DEAD DEAH box helicase deaD3 - 3.6.4.13 ko:K05592 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,Helicase_C k141_15041_1 1042377.AFPJ01000030_gene447 1.49e-41 152.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MV8W@1224|Proteobacteria,1RMQA@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Outer membrane receptor proteins mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec k141_15041_2 1123053.AUDG01000059_gene440 3.72e-171 492.0 COG2367@1|root,COG2367@2|Bacteria,1MZ00@1224|Proteobacteria,1S835@1236|Gammaproteobacteria,1X0VS@135613|Chromatiales 135613|Chromatiales V Beta-lactamase enzyme family - - - - - - - - - - - - Beta-lactamase2 k141_15041_3 1545915.JROG01000004_gene2038 1.34e-46 158.0 COG1416@1|root,COG1416@2|Bacteria,1RI2V@1224|Proteobacteria,2U98Z@28211|Alphaproteobacteria,2K5CI@204457|Sphingomonadales 204457|Sphingomonadales S DsrE/DsrF-like family - - - - - - - - - - - - DrsE k141_15041_4 28229.ND2E_3695 2.27e-46 155.0 COG3148@1|root,COG3148@2|Bacteria,1N0GQ@1224|Proteobacteria,1SAQQ@1236|Gammaproteobacteria,2Q834@267889|Colwelliaceae 1236|Gammaproteobacteria S DTW - - - - - - - - - - - - DTW k141_15041_6 1279017.AQYJ01000027_gene1949 0.0 1217.0 COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,1RMWP@1236|Gammaproteobacteria,4651B@72275|Alteromonadaceae 1236|Gammaproteobacteria G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate tkt - 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C,Transketolase_N k141_15041_7 1042377.AFPJ01000032_gene2738 6.14e-163 464.0 COG0500@1|root,COG0640@1|root,COG0640@2|Bacteria,COG2226@2|Bacteria,1NFSV@1224|Proteobacteria,1RQT6@1236|Gammaproteobacteria,464PH@72275|Alteromonadaceae 1236|Gammaproteobacteria K Transcriptional regulators - - - - - - - - - - - - HTH_20,HTH_5,Methyltransf_11,Methyltransf_23,Methyltransf_31 k141_15041_9 1279017.AQYJ01000027_gene1952 0.0 887.0 COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,1RMW8@1236|Gammaproteobacteria,464HR@72275|Alteromonadaceae 1236|Gammaproteobacteria H May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine ahcY GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 ko:K01251 ko00270,ko01100,map00270,map01100 M00035 R00192,R04936 RC00056,RC00069,RC01161,RC01243 ko00000,ko00001,ko00002,ko01000,ko01009,ko04147 - - iYL1228.KPN_02462 AdoHcyase,AdoHcyase_NAD k141_15041_11 1279017.AQYJ01000027_gene1961 4.52e-55 180.0 COG2885@1|root,COG2885@2|Bacteria,1REH1@1224|Proteobacteria,1S4WV@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Belongs to the ompA family - - - - - - - - - - - - DUF4398,OmpA k141_15041_12 1279017.AQYJ01000027_gene1960 2.35e-118 342.0 COG0637@1|root,COG0637@2|Bacteria,1NSPA@1224|Proteobacteria,1RQET@1236|Gammaproteobacteria,467TI@72275|Alteromonadaceae 1236|Gammaproteobacteria S Haloacid dehalogenase-like hydrolase - - - - - - - - - - - - HAD_2 k141_15041_14 1279017.AQYJ01000027_gene1958 3.28e-122 354.0 COG1385@1|root,COG1385@2|Bacteria,1MXCU@1224|Proteobacteria,1RPBN@1236|Gammaproteobacteria,466M1@72275|Alteromonadaceae 1236|Gammaproteobacteria J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit rsmE GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.193 ko:K09761 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_RNA k141_15041_15 1042377.AFPJ01000032_gene2750 0.0 1671.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,464X3@72275|Alteromonadaceae 1236|Gammaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran k141_15041_16 1279017.AQYJ01000027_gene1956 5.76e-197 557.0 COG0845@1|root,COG0845@2|Bacteria,1PEVY@1224|Proteobacteria,1RPEQ@1236|Gammaproteobacteria,465PN@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - - - - - - - - - - Biotin_lipoyl_2,HlyD_3 k141_15041_17 1042377.AFPJ01000032_gene2752 0.0 1385.0 COG2183@1|root,COG2183@2|Bacteria,1MUA7@1224|Proteobacteria,1RMNH@1236|Gammaproteobacteria,464NC@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG2183 Transcriptional accessory protein yhgF GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0044424,GO:0044444,GO:0044464,GO:0050896 - ko:K06959 - - - - ko00000 - - - HHH_3,S1,Tex_N,Tex_YqgF k141_15041_18 203122.Sde_1709 4.63e-139 402.0 COG1082@1|root,COG1082@2|Bacteria,1RB2C@1224|Proteobacteria,1S292@1236|Gammaproteobacteria,466F9@72275|Alteromonadaceae 1236|Gammaproteobacteria G Xylose isomerase-like TIM barrel - - - - - - - - - - - - AP_endonuc_2 k141_15041_19 247639.MGP2080_02371 7.49e-20 96.7 COG2207@1|root,COG2207@2|Bacteria,1MX23@1224|Proteobacteria,1RN7K@1236|Gammaproteobacteria,1J6BN@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria K COG2207 AraC-type DNA-binding domain-containing proteins - - - - - - - - - - - - Arabinose_bd,HTH_18 k141_15041_20 1116375.VEJY3_02945 1.47e-43 152.0 2BN4A@1|root,32GR8@2|Bacteria,1RHQ4@1224|Proteobacteria,1S86P@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_15041_23 1380387.JADM01000002_gene2008 1.04e-30 118.0 COG2808@1|root,COG2808@2|Bacteria,1N1B9@1224|Proteobacteria,1S7MT@1236|Gammaproteobacteria,1XMCI@135619|Oceanospirillales 135619|Oceanospirillales K Putative FMN-binding domain - - - ko:K07734 - - - - ko00000,ko03000 - - - FMN_bind_2 k141_15041_24 190650.CC_3179 3.05e-50 177.0 COG2159@1|root,COG2159@2|Bacteria,1PTY1@1224|Proteobacteria,2V5RF@28211|Alphaproteobacteria,2KHVI@204458|Caulobacterales 204458|Caulobacterales S Amidohydrolase - - - ko:K07045 - - - - ko00000 - - - Amidohydro_2 k141_15041_25 1279017.AQYJ01000027_gene1962 2.79e-254 711.0 COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,1RMGJ@1236|Gammaproteobacteria,46A3P@72275|Alteromonadaceae 1236|Gammaproteobacteria Q COG1233 Phytoene dehydrogenase and related proteins - - 1.3.99.23 ko:K09516 ko00830,map00830 - R07163 RC01835 ko00000,ko00001,ko01000 - - - Amino_oxidase,FAD_binding_6,NAD_binding_1,NAD_binding_8 k141_5717_2 218284.CCDN010000001_gene1910 8.1e-90 271.0 COG0455@1|root,COG0455@2|Bacteria,1TRZ5@1239|Firmicutes,4HCWZ@91061|Bacilli,1ZE3G@1386|Bacillus 91061|Bacilli D Belongs to the ParA family ylxH - - ko:K04562 - - - - ko00000,ko02035 - - - AAA_31,CbiA,ParA k141_23670_1 218284.CCDN010000002_gene1996 3.87e-104 309.0 COG1470@1|root,COG1470@2|Bacteria,1TRGE@1239|Firmicutes,4HBPI@91061|Bacilli,1ZB6W@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3048) C-terminal domain yerB - - - - - - - - - - - DUF3048,DUF3048_C k141_1184_3 1042377.AFPJ01000052_gene1590 0.0 930.0 COG3104@1|root,COG3104@2|Bacteria,1MW6W@1224|Proteobacteria,1RM8P@1236|Gammaproteobacteria,4643X@72275|Alteromonadaceae 1236|Gammaproteobacteria E POT family dtpT - - ko:K03305 - - - - ko00000 2.A.17 - - PTR2 k141_37765_1 218284.CCDN010000006_gene3527 5.58e-120 350.0 COG0614@1|root,COG0614@2|Bacteria,1TR63@1239|Firmicutes,4HB8N@91061|Bacilli,1ZCYN@1386|Bacillus 91061|Bacilli P ABC transporter substrate-binding protein yfiY - - ko:K02016 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - Peripla_BP_2 k141_10583_1 1294265.JCM21738_943 2.23e-124 355.0 29RSI@1|root,30CWB@2|Bacteria,1UAGG@1239|Firmicutes,4IKUX@91061|Bacilli,1ZHQS@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_20203_1 1236973.JCM9157_2098 8.9e-31 119.0 COG1820@1|root,COG1820@2|Bacteria,1TPFK@1239|Firmicutes,4HC6C@91061|Bacilli,1ZCM7@1386|Bacillus 91061|Bacilli G Belongs to the metallo-dependent hydrolases superfamily. NagA family nagA GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005515,GO:0006040,GO:0006044,GO:0006046,GO:0008150,GO:0008152,GO:0008448,GO:0009056,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046348,GO:0046872,GO:0046914,GO:0046983,GO:0071704,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901575 3.5.1.25 ko:K01443 ko00520,ko01130,map00520,map01130 - R02059 RC00166,RC00300 ko00000,ko00001,ko01000 - - - Amidohydro_1 k141_20203_2 272558.10173033 5.68e-76 234.0 COG0363@1|root,COG0363@2|Bacteria,1TP10@1239|Firmicutes,4HAG4@91061|Bacilli,1ZD28@1386|Bacillus 91061|Bacilli G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion nagB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 3.5.99.6 ko:K02564 ko00520,ko01100,map00520,map01100 - R00765 RC00163 ko00000,ko00001,ko01000 - - iYO844.BSU35020 Glucosamine_iso k141_31627_1 1453501.JELR01000002_gene411 2.44e-09 56.6 2C2E6@1|root,2ZPXX@2|Bacteria,1N6U8@1224|Proteobacteria,1SEU1@1236|Gammaproteobacteria 1236|Gammaproteobacteria S assembly protein CsgE csgE - - ko:K04337 - - - - ko00000,ko02044 - - - CsgE k141_31627_2 1042377.AFPJ01000051_gene39 9.54e-75 230.0 COG2197@1|root,COG2197@2|Bacteria,1NI3Z@1224|Proteobacteria,1SJ39@1236|Gammaproteobacteria 1236|Gammaproteobacteria KT helix_turn_helix, Lux Regulon - - - ko:K04333 ko02026,map02026 - - - ko00000,ko00001,ko03000 - - - GerE k141_24933_1 796606.BMMGA3_12570 9.48e-18 84.0 2BA87@1|root,323NA@2|Bacteria,1V54Z@1239|Firmicutes,4HGZH@91061|Bacilli,1ZIG0@1386|Bacillus 91061|Bacilli - - - - - ko:K02664 - - - - ko00000,ko02035,ko02044 - - - LysM,PilO k141_29630_1 1279017.AQYJ01000028_gene2321 4.71e-61 216.0 COG2982@1|root,COG2982@2|Bacteria,1MUME@1224|Proteobacteria,1RNPC@1236|Gammaproteobacteria,464KK@72275|Alteromonadaceae 1236|Gammaproteobacteria M Domain of Unknown Function (DUF748) - - - - - - - - - - - - DUF748,OmpA k141_7992_1 218284.CCDN010000002_gene2261 2.04e-72 225.0 28IN6@1|root,2Z8NK@2|Bacteria,1TR7N@1239|Firmicutes,4HBDQ@91061|Bacilli,1ZBTH@1386|Bacillus 91061|Bacilli S YfkD-like protein yfkD - - - - - - - - - - - YfkD k141_4569_1 1385513.N780_17640 2.42e-118 369.0 COG2273@1|root,COG2273@2|Bacteria,1TR5U@1239|Firmicutes,4HB9D@91061|Bacilli,2YB4A@289201|Pontibacillus 91061|Bacilli G PFAM glycoside hydrolase family 16 - - - - - - - - - - - - CBM_4_9,Glyco_hydro_16,SLH k141_10584_1 218284.CCDN010000005_gene3467 2.91e-59 187.0 28K3D@1|root,2Z9SI@2|Bacteria,1UZKH@1239|Firmicutes,4HDH6@91061|Bacilli,1ZI4E@1386|Bacillus 91061|Bacilli S MEDS: MEthanogen/methylotroph, DcmR Sensory domain - - - - - - - - - - - - MEDS k141_2131_1 218284.CCDN010000001_gene1523 4.29e-131 373.0 COG0693@1|root,COG0693@2|Bacteria,1UG8E@1239|Firmicutes,4HCBM@91061|Bacilli,1ZENU@1386|Bacillus 91061|Bacilli S DJ-1/PfpI family - - - - - - - - - - - - DJ-1_PfpI k141_17639_1 1453501.JELR01000002_gene666 8.96e-97 291.0 COG0624@1|root,COG0624@2|Bacteria,1MVBR@1224|Proteobacteria,1RNDG@1236|Gammaproteobacteria,4653S@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the peptidase M20A family. ArgE subfamily argE GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0008777,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019752,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0046914,GO:0050897,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.1.16 ko:K01438 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R00669,R09107 RC00064,RC00300 ko00000,ko00001,ko00002,ko01000 - - iECUMN_1333.ECUMN_4488 M20_dimer,Peptidase_M20,Peptidase_M28 k141_34342_1 42565.FP66_02460 4.85e-06 44.7 2954Q@1|root,2ZSHA@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k141_34342_2 42565.FP66_02455 2.9e-130 374.0 COG1737@1|root,COG1737@2|Bacteria,1MV3U@1224|Proteobacteria,1RNC4@1236|Gammaproteobacteria,1XJ1F@135619|Oceanospirillales 135619|Oceanospirillales K transcriptional regulator - - - ko:K19337 - - - - ko00000,ko03000 - - - HTH_6,SIS k141_29631_1 218284.CCDN010000004_gene3092 2.39e-141 408.0 COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,1TR88@1239|Firmicutes,4HBF3@91061|Bacilli,1ZCMJ@1386|Bacillus 91061|Bacilli T Histidine kinase yhcY - 2.7.13.3 ko:K02480 - - - - ko00000,ko01000,ko01001,ko02022 - - - GAF_2,HATPase_c,HisKA_3 k141_24935_1 218284.CCDN010000008_gene4163 2.51e-95 283.0 COG1506@1|root,COG1506@2|Bacteria,1U5SB@1239|Firmicutes,4HB1A@91061|Bacilli,1ZC9W@1386|Bacillus 91061|Bacilli E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases ytmA - - - - - - - - - - - Peptidase_S9 k141_20205_1 1453501.JELR01000002_gene178 2e-120 363.0 COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,1RQIX@1236|Gammaproteobacteria,4669Y@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0457 FOG TPR repeat - - - - - - - - - - - - TPR_14,TPR_16,TPR_19,TPR_2,TPR_6,TPR_8 k141_37768_1 260799.BAS1171 5.45e-47 157.0 COG5628@1|root,COG5628@2|Bacteria,1V3M6@1239|Firmicutes,4HHX0@91061|Bacilli,1ZG8S@1386|Bacillus 91061|Bacilli S Acetyltransferase (GNAT) family - - - - - - - - - - - - Acetyltransf_1 k141_16492_4 768671.ThimaDRAFT_1732 2.33e-110 330.0 COG4313@1|root,COG4313@2|Bacteria,1PC95@1224|Proteobacteria,1RZJZ@1236|Gammaproteobacteria,1WZES@135613|Chromatiales 135613|Chromatiales C Putative MetA-pathway of phenol degradation - - - - - - - - - - - - Phenol_MetA_deg k141_16492_5 1453501.JELR01000002_gene1022 1.71e-133 385.0 COG0388@1|root,COG0388@2|Bacteria,1MUUB@1224|Proteobacteria,1RNVZ@1236|Gammaproteobacteria,466U1@72275|Alteromonadaceae 1236|Gammaproteobacteria S amidohydrolase ramA - 3.5.5.1 ko:K01501,ko:K11206 ko00380,ko00460,ko00627,ko00643,ko00910,ko01120,map00380,map00460,map00627,map00643,map00910,map01120 - R00540,R01887,R03093,R03542,R05591,R07855 RC00315,RC00325,RC00617,RC00959,RC02811 ko00000,ko00001,ko01000 - - - CN_hydrolase k141_16492_6 1535422.ND16A_3283 4.66e-178 531.0 COG0823@1|root,COG3710@1|root,COG0823@2|Bacteria,COG3710@2|Bacteria,1RIFT@1224|Proteobacteria,1S7XY@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Transcriptional regulatory protein, C terminal - - - - - - - - - - - - PD40,Trans_reg_C k141_16492_7 1122194.AUHU01000006_gene430 2.88e-93 308.0 COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,1RYK4@1236|Gammaproteobacteria,468MV@72275|Alteromonadaceae 1236|Gammaproteobacteria V Beta-lactamase - - - - - - - - - - - - Beta-lactamase k141_16492_8 1042377.AFPJ01000054_gene1687 2.99e-118 362.0 COG0308@1|root,COG0308@2|Bacteria,1NY0A@1224|Proteobacteria,1SPZ9@1236|Gammaproteobacteria 1236|Gammaproteobacteria E aminopeptidase N - - - - - - - - - - - - - k141_16492_9 1121887.AUDK01000026_gene1939 1.32e-66 216.0 COG2017@1|root,COG2017@2|Bacteria,4NMWB@976|Bacteroidetes,1HWV5@117743|Flavobacteriia,2NS9G@237|Flavobacterium 976|Bacteroidetes G Aldose 1-epimerase lacX - - - - - - - - - - - Aldose_epim k141_16492_10 1042377.AFPJ01000042_gene1032 2.05e-99 296.0 COG3010@1|root,COG3010@2|Bacteria,1PRVW@1224|Proteobacteria,1RS59@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) nanE GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006040,GO:0006050,GO:0006051,GO:0006053,GO:0006054,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016853,GO:0016854,GO:0016857,GO:0016999,GO:0017001,GO:0017144,GO:0019262,GO:0019752,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046346,GO:0046348,GO:0046395,GO:0047465,GO:0071704,GO:1901135,GO:1901136,GO:1901575 5.1.3.9 ko:K01788 ko00520,map00520 - R02087 RC00290 ko00000,ko00001,ko01000 - - iB21_1397.B21_03034,iECBD_1354.ECBD_0524,iECB_1328.ECB_03083,iECD_1391.ECD_03083,iEcHS_1320.EcHS_A3411,iEcolC_1368.EcolC_0483,iSFV_1184.SFV_3248,iSF_1195.SF3259,iSFxv_1172.SFxv_3571,iS_1188.S3476,iUTI89_1310.UTI89_C3653,ic_1306.c3977 NanE k141_16492_11 1042377.AFPJ01000042_gene1031 2.32e-128 370.0 COG2188@1|root,COG2188@2|Bacteria,1MUEB@1224|Proteobacteria,1RYZ9@1236|Gammaproteobacteria,4688D@72275|Alteromonadaceae 1236|Gammaproteobacteria K UTRA - - - ko:K03710 - - - - ko00000,ko03000 - - - GntR,UTRA k141_16492_12 1042377.AFPJ01000042_gene1030 1.46e-67 219.0 COG1653@1|root,COG1653@2|Bacteria,1MUNZ@1224|Proteobacteria,1RP01@1236|Gammaproteobacteria,465XT@72275|Alteromonadaceae 1236|Gammaproteobacteria G ABC-type sugar transport system, periplasmic component mtlE - - ko:K10227 ko02010,map02010 M00200 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.5 - - SBP_bac_1 k141_3362_1 218284.CCDN010000002_gene2726 5.11e-80 244.0 COG1366@1|root,COG1366@2|Bacteria,1V1QF@1239|Firmicutes,4HGBT@91061|Bacilli,1ZDJX@1386|Bacillus 91061|Bacilli T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) - - - ko:K17763 - - - - ko00000,ko03021 - - - STAS k141_29632_1 935836.JAEL01000068_gene1772 1.16e-103 312.0 COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TPJ8@1239|Firmicutes,4HA8X@91061|Bacilli,1ZAZ3@1386|Bacillus 91061|Bacilli G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific nagE - 2.7.1.193,2.7.1.199 ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 M00267,M00809 R02738,R05199 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.13,4.A.1.1.14,4.A.1.1.15,4.A.1.1.2,4.A.1.1.5,4.A.1.1.7,4.A.1.1.9 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC k141_20206_1 218284.CCDN010000001_gene1510 3.14e-92 284.0 COG1921@1|root,COG1921@2|Bacteria,1TQT8@1239|Firmicutes,4HAAC@91061|Bacilli,1ZCFY@1386|Bacillus 91061|Bacilli E Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis selA - 2.9.1.1 ko:K01042 ko00450,ko00970,map00450,map00970 - R08219 RC01246 ko00000,ko00001,ko01000 - - - Se-cys_synth_N,SelA k141_31628_3 1286632.P278_31220 1.38e-96 291.0 COG4099@1|root,COG4099@2|Bacteria,4NFSH@976|Bacteroidetes,1HY30@117743|Flavobacteriia 976|Bacteroidetes E Phospholipase - - - - - - - - - - - - Abhydrolase_2,Esterase_phd,Peptidase_S9 k141_37770_1 391625.PPSIR1_31323 5.79e-51 179.0 COG1966@1|root,COG1966@2|Bacteria,1MWF9@1224|Proteobacteria,42NBI@68525|delta/epsilon subdivisions,2WM33@28221|Deltaproteobacteria,2YUS1@29|Myxococcales 28221|Deltaproteobacteria T Carbon starvation protein cstA - - ko:K06200 - - - - ko00000 - - - CstA,CstA_5TM k141_29634_1 558169.AGAV01000007_gene1326 4.81e-71 222.0 COG1230@1|root,COG1230@2|Bacteria,1TR92@1239|Firmicutes,4HBCQ@91061|Bacilli 91061|Bacilli P cation diffusion facilitator family transporter czcD - - ko:K16264 - - - - ko00000,ko02000 2.A.4.1 - - Cation_efflux,ZT_dimer k141_20207_1 1453501.JELR01000001_gene2245 8.69e-115 346.0 COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,1RQ4N@1236|Gammaproteobacteria,4648E@72275|Alteromonadaceae 1236|Gammaproteobacteria Q multicopper oxidases pcoA - - - - - - - - - - - CopB,Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3 k141_2134_1 1294265.JCM21738_960 2.79e-39 141.0 COG0596@1|root,COG0596@2|Bacteria,1V619@1239|Firmicutes,4HCRW@91061|Bacilli,1ZDX1@1386|Bacillus 91061|Bacilli S Serine aminopeptidase, S33 yvaM - 1.11.1.10 ko:K00433 - - - - ko00000,ko01000 - - - Abhydrolase_1,Hydrolase_4 k141_24938_1 1294265.JCM21738_4001 4.64e-115 330.0 COG1399@1|root,COG1399@2|Bacteria,1VB08@1239|Firmicutes,4HME9@91061|Bacilli,1ZGJH@1386|Bacillus 91061|Bacilli S metal-binding, possibly nucleic acid-binding protein ylbN - - ko:K07040 - - - - ko00000 - - - DUF177 k141_7996_1 1165841.SULAR_00300 6.15e-18 86.7 COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,42PKA@68525|delta/epsilon subdivisions,2YP35@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria J Belongs to the protein N5-glutamine methyltransferase family hemK - 2.1.1.297 ko:K02493 - - R10806 RC00003,RC03279 ko00000,ko01000,ko03012 - - - MTS k141_7996_2 459349.CLOAM0175 2.88e-63 204.0 COG0216@1|root,COG0216@2|Bacteria,2NNKY@2323|unclassified Bacteria 2|Bacteria J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA prfA - - ko:K02835 - - - - ko00000,ko03012 - - - PCRF,RF-1 k141_36466_1 218284.CCDN010000008_gene4188 2.19e-129 378.0 COG2081@1|root,COG2081@2|Bacteria,1TQ6E@1239|Firmicutes,4HAAT@91061|Bacilli,1ZAT3@1386|Bacillus 91061|Bacilli S HI0933-like protein ytfP - - ko:K07007 - - - - ko00000 - - - HI0933_like k141_37771_1 314254.OA2633_09879 3.56e-11 63.2 COG1028@1|root,COG1028@2|Bacteria,1MUBQ@1224|Proteobacteria,2TRPN@28211|Alphaproteobacteria,43W99@69657|Hyphomonadaceae 28211|Alphaproteobacteria IQ Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short,adh_short_C2 k141_37771_2 34007.IT40_25180 9e-98 297.0 COG1804@1|root,COG1804@2|Bacteria,1MW1H@1224|Proteobacteria,2TR7D@28211|Alphaproteobacteria,2PWGY@265|Paracoccus 28211|Alphaproteobacteria C CoA-transferase family III - - 5.1.99.4 ko:K01796 ko00120,ko01100,ko04146,map00120,map01100,map04146 M00104 R08734,R08739 RC02345 ko00000,ko00001,ko00002,ko01000 - - - CoA_transf_3 k141_34343_2 1279017.AQYJ01000028_gene2327 2.33e-77 237.0 COG3839@1|root,COG3839@2|Bacteria,1QXG5@1224|Proteobacteria,1T3B9@1236|Gammaproteobacteria,46AQA@72275|Alteromonadaceae 1236|Gammaproteobacteria G ATPases associated with a variety of cellular activities - - - - - - - - - - - - ABC_tran k141_34343_3 1453501.JELR01000005_gene1671 7.06e-118 344.0 COG0390@1|root,COG0390@2|Bacteria,1MV2N@1224|Proteobacteria,1RSGA@1236|Gammaproteobacteria,467K7@72275|Alteromonadaceae 1236|Gammaproteobacteria S Uncharacterised protein family (UPF0014) ybbM GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0009987,GO:0015075,GO:0016020,GO:0016021,GO:0019725,GO:0022857,GO:0030003,GO:0031224,GO:0031226,GO:0034220,GO:0042592,GO:0044425,GO:0044459,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071944,GO:0098771 - ko:K02069 - M00211 - - ko00000,ko00002,ko02000 9.B.25.1 - - UPF0014 k141_31630_1 218284.CCDN010000006_gene3595 1.22e-69 219.0 COG1622@1|root,COG1622@2|Bacteria,1TPF6@1239|Firmicutes,4HA9J@91061|Bacilli,1ZB28@1386|Bacillus 91061|Bacilli C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I qoxA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009055,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015002,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0016491,GO:0016679,GO:0016682,GO:0017144,GO:0019637,GO:0019693,GO:0022857,GO:0022890,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1902600 1.10.3.12 ko:K02826 ko00190,ko01100,map00190,map01100 M00416 R09492 RC00819 ko00000,ko00001,ko00002,ko01000 3.D.4.1 - iSB619.SA_RS05175 COX2,COX2_TM k141_36467_2 265729.GS18_0214535 0.000346 42.0 COG1108@1|root,COG1108@2|Bacteria,1TPZB@1239|Firmicutes,4HBD7@91061|Bacilli,1ZAY6@1386|Bacillus 91061|Bacilli P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components' mntD GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0010035,GO:0010038,GO:0010043,GO:0016020,GO:0042221,GO:0044464,GO:0050896,GO:0071944 - ko:K11709,ko:K19976 ko02010,map02010 M00319,M00792 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15,3.A.1.15.15 - - ABC-3 k141_24939_2 218284.CCDN010000001_gene1191 8.07e-167 484.0 COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4H9TK@91061|Bacilli,1ZBTF@1386|Bacillus 91061|Bacilli S COG0488 ATPase components of ABC transporters with duplicated ATPase domains yfmR - - ko:K15738 - - - - ko00000,ko02000 3.A.1.120.6 - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn k141_29636_1 1234664.AMRO01000027_gene1293 2.84e-86 263.0 COG2805@1|root,COG2805@2|Bacteria,1TQ5F@1239|Firmicutes,4H9RK@91061|Bacilli,1WEGE@129337|Geobacillus 91061|Bacilli NU Type II/IV secretion system protein pilT - - ko:K02669 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE k141_29636_2 1034347.CAHJ01000039_gene4796 8.93e-139 407.0 COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,4HB0C@91061|Bacilli,1ZD5J@1386|Bacillus 91061|Bacilli NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB pilB - - ko:K02243,ko:K02652 - M00429 - - ko00000,ko00002,ko02035,ko02044 3.A.14.1,3.A.15.2 - - T2SSE,T2SSE_N k141_17643_1 218284.CCDN010000002_gene2855 0.0 1117.0 COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1TQ0B@1239|Firmicutes,4HA4G@91061|Bacilli,1ZBFF@1386|Bacillus 91061|Bacilli E glutamate synthase gltA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14,1.4.7.1 ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 - R00021,R00093,R00114,R00248,R10086 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - GATase_2,GXGXG,Glu_syn_central,Glu_synthase k141_34344_1 218284.CCDN010000001_gene1405 9.1e-76 230.0 COG0425@1|root,COG0607@1|root,COG0425@2|Bacteria,COG0607@2|Bacteria,1V1GU@1239|Firmicutes,4HFR8@91061|Bacilli,1ZAVN@1386|Bacillus 91061|Bacilli OP Belongs to the sulfur carrier protein TusA family yrkF - - - - - - - - - - - Rhodanese,TusA k141_34344_2 1220589.CD32_22240 2.41e-53 177.0 COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,1TPE2@1239|Firmicutes,4H9WH@91061|Bacilli,3IVPA@400634|Lysinibacillus 91061|Bacilli P Rhodanese Homology Domain yrkH - - - - - - - - - - - Lactamase_B,Rhodanese k141_17663_2 1395513.P343_08350 8.76e-40 142.0 COG0596@1|root,COG0596@2|Bacteria,1TS4C@1239|Firmicutes,4HB6G@91061|Bacilli,26PKP@186821|Sporolactobacillaceae 91061|Bacilli S Alpha/beta hydrolase family menH GO:0003674,GO:0003824,GO:0016787 4.2.99.20 ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R08166 RC02148,RC02475 ko00000,ko00001,ko00002,ko01000 - - - Abhydrolase_1 k141_10592_3 440512.C211_14281 9.84e-20 99.4 COG2199@1|root,COG3706@2|Bacteria,1R51K@1224|Proteobacteria,1SYWV@1236|Gammaproteobacteria 1236|Gammaproteobacteria T COG2202 FOG PAS PAC domain - - - - - - - - - - - - GGDEF,PAS_9 k141_21173_1 218284.CCDN010000001_gene1071 1.84e-26 110.0 COG0514@1|root,COG0514@2|Bacteria,1TPN5@1239|Firmicutes,4H9QP@91061|Bacilli,1ZB1X@1386|Bacillus 91061|Bacilli L DNA helicase recQ GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009378,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.6.4.12 ko:K03654 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecQ_Zn_bind k141_24961_1 1294265.JCM21738_288 1.34e-102 298.0 COG5405@1|root,COG5405@2|Bacteria,1TPXK@1239|Firmicutes,4H9PD@91061|Bacilli,1ZCMN@1386|Bacillus 91061|Bacilli O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery hslV - 3.4.25.2 ko:K01419 - - - - ko00000,ko01000,ko01002 - - - Proteasome k141_33104_1 218284.CCDN010000005_gene3381 1.97e-19 80.9 COG0599@1|root,COG0599@2|Bacteria,1V8W7@1239|Firmicutes,4HHDQ@91061|Bacilli,1ZGYY@1386|Bacillus 91061|Bacilli S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity yurZ - - - - - - - - - - - CMD k141_33104_2 218284.CCDN010000006_gene3501 3.63e-181 506.0 COG1464@1|root,COG1464@2|Bacteria,1TQAS@1239|Firmicutes,4HBK0@91061|Bacilli,1ZATZ@1386|Bacillus 91061|Bacilli P Belongs to the NlpA lipoprotein family metQ - - ko:K02072,ko:K02073 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - Lipoprotein_9 k141_29655_1 218284.CCDN010000001_gene1929 1.8e-195 550.0 COG1157@1|root,COG1157@2|Bacteria,1TP0R@1239|Firmicutes,4HAUY@91061|Bacilli,1ZBXU@1386|Bacillus 91061|Bacilli NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase fliI - 3.6.3.14 ko:K02412 ko02040,map02040 - - - ko00000,ko00001,ko01000,ko02035,ko02044 3.A.6.2,3.A.6.3 - - ATP-synt_ab,ATP-synt_ab_N k141_36486_1 218284.CCDN010000001_gene690 1.2e-183 533.0 COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,4H9XC@91061|Bacilli,1ZB9E@1386|Bacillus 91061|Bacilli J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain alaS GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DHHA1,tRNA-synt_2c,tRNA_SAD k141_21174_1 935836.JAEL01000083_gene1125 4.91e-90 269.0 COG2186@1|root,COG2186@2|Bacteria,1V2TU@1239|Firmicutes,4HDHI@91061|Bacilli,1ZD1T@1386|Bacillus 91061|Bacilli K COG2186 Transcriptional regulators yvfI - - ko:K05799 - - - - ko00000,ko03000 - - - FCD,GntR k141_10594_1 218284.CCDN010000001_gene717 8.36e-105 305.0 COG1713@1|root,COG1713@2|Bacteria,1V6Y1@1239|Firmicutes,4HHRY@91061|Bacilli,1ZCQJ@1386|Bacillus 91061|Bacilli H HD superfamily hydrolase involved in NAD metabolism yqeK - - - - - - - - - - - HD k141_16504_2 218284.CCDN010000007_gene3875 6.48e-140 400.0 COG0154@1|root,COG0154@2|Bacteria,1UZ2V@1239|Firmicutes,4HE70@91061|Bacilli,1ZDE6@1386|Bacillus 91061|Bacilli J Gas vesicle synthesis protein GvpL/GvpF - - - - - - - - - - - - GvpL_GvpF k141_16504_3 218284.CCDN010000007_gene3876 1.53e-43 142.0 2DNWP@1|root,32ZJU@2|Bacteria,1VGW6@1239|Firmicutes,4HQAB@91061|Bacilli,1ZIGU@1386|Bacillus 91061|Bacilli S Gas vesicle protein G gvpG - - - - - - - - - - - GvpG k141_2155_1 216596.pRL120546 8.34e-09 55.1 COG4221@1|root,COG4221@2|Bacteria,1MUF8@1224|Proteobacteria,2TUSA@28211|Alphaproteobacteria,4B809@82115|Rhizobiaceae 28211|Alphaproteobacteria S Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short k141_2155_2 1177179.A11A3_07273 1.92e-37 128.0 COG1917@1|root,COG1917@2|Bacteria,1RH1V@1224|Proteobacteria,1S3RV@1236|Gammaproteobacteria 1236|Gammaproteobacteria S conserved protein, contains double-stranded beta-helix domain - - - - - - - - - - - - Cupin_2 k141_28219_1 1453501.JELR01000002_gene1203 8.76e-85 255.0 COG1309@1|root,COG1309@2|Bacteria,1RHF5@1224|Proteobacteria,1S8K9@1236|Gammaproteobacteria,468RJ@72275|Alteromonadaceae 1236|Gammaproteobacteria K Transcriptional regulator - - - - - - - - - - - - TetR_C_13,TetR_N k141_36487_1 674977.VMC_18690 4.06e-211 607.0 COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,1RNEB@1236|Gammaproteobacteria,1XTVJ@135623|Vibrionales 135623|Vibrionales J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner valS GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 k141_10595_1 1294265.JCM21738_208 5.38e-62 199.0 COG3424@1|root,COG3424@2|Bacteria,1TPUK@1239|Firmicutes,4HBHH@91061|Bacilli,1ZC8W@1386|Bacillus 91061|Bacilli Q Naringenin-chalcone synthase bcsA - - ko:K16167 - - - - ko00000,ko01008 - - - Chal_sti_synt_C,Chal_sti_synt_N k141_10595_2 1294265.JCM21738_209 4.77e-47 155.0 COG1755@1|root,COG1755@2|Bacteria,1V6IY@1239|Firmicutes,4HIFN@91061|Bacilli,1ZGT0@1386|Bacillus 91061|Bacilli S protein conserved in bacteria ypbQ - - ko:K16168 - - - - ko00000,ko01008 - - - ICMT k141_17666_1 218284.CCDN010000001_gene221 1.06e-168 473.0 COG0061@1|root,COG0061@2|Bacteria,1TRXB@1239|Firmicutes,4HCEW@91061|Bacilli,1ZB1S@1386|Bacillus 91061|Bacilli G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP nadK2 - 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 - R00104 RC00002,RC00078 ko00000,ko00001,ko01000 - - - NAD_kinase k141_2156_1 218284.CCDN010000005_gene3415 3.02e-83 254.0 COG2334@1|root,COG2334@2|Bacteria,1VEZ6@1239|Firmicutes,4HBAB@91061|Bacilli,1ZBAM@1386|Bacillus 91061|Bacilli S Spore coat protein yutH GO:0005575,GO:0005623,GO:0042601,GO:0042763,GO:0044464 - - - - - - - - - - - k141_24963_2 218284.CCDN010000001_gene695 4.76e-109 318.0 COG4122@1|root,COG4122@2|Bacteria,1UF4M@1239|Firmicutes,4HE9E@91061|Bacilli,1ZFK8@1386|Bacillus 91061|Bacilli S O-methyltransferase yrrM - 2.1.1.104 ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 M00039,M00350 R01942,R06578 RC00003,RC00392 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_3 k141_24963_3 279010.BL02027 5.54e-05 44.3 COG0826@1|root,COG0826@2|Bacteria,1TQIZ@1239|Firmicutes,4HA2T@91061|Bacilli,1ZAXB@1386|Bacillus 91061|Bacilli O Peptidase U32 yrrN - - ko:K08303 ko05120,map05120 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_U32 k141_17667_1 218284.CCDN010000006_gene3685 6.58e-89 284.0 COG0653@1|root,COG0653@2|Bacteria,1TPEY@1239|Firmicutes,4HA22@91061|Bacilli,1ZAXF@1386|Bacillus 91061|Bacilli U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW k141_15207_1 42565.FP66_02995 8.95e-118 348.0 COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,1SKAB@1236|Gammaproteobacteria,1XNC6@135619|Oceanospirillales 135619|Oceanospirillales Q transporter - - - - - - - - - - - - DctM k141_10596_1 1128421.JAGA01000004_gene2670 7.73e-17 75.5 COG0346@1|root,COG0346@2|Bacteria 2|Bacteria E lactoylglutathione lyase activity - - 5.1.99.1 ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00373,M00375,M00376,M00741 R02765,R09979 RC00780,RC02739 ko00000,ko00001,ko00002,ko01000 - - - Glyoxalase k141_10596_2 580332.Slit_2268 3.17e-62 198.0 COG3797@1|root,COG3797@2|Bacteria,1N0SN@1224|Proteobacteria,2WAUM@28216|Betaproteobacteria,44WGD@713636|Nitrosomonadales 28216|Betaproteobacteria S Protein of unknown function (DUF1697) - - - - - - - - - - - - DUF1697 k141_36489_1 1131462.DCF50_p1820 8.3e-17 79.0 2DYW6@1|root,32V64@2|Bacteria,1VDSX@1239|Firmicutes,24R5C@186801|Clostridia,2665Z@186807|Peptococcaceae 186801|Clostridia S Bacteriophage replication protein O - - - - - - - - - - - - Phage_rep_O k141_33106_1 42565.FP66_07680 2.21e-107 310.0 COG0801@1|root,COG0801@2|Bacteria,1RHNN@1224|Proteobacteria,1S62M@1236|Gammaproteobacteria,1XJZ9@135619|Oceanospirillales 135619|Oceanospirillales H COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase folK - 2.7.6.3 ko:K00950 ko00790,ko01100,map00790,map01100 M00126,M00841 R03503 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - HPPK k141_33106_2 42565.FP66_07685 2.11e-66 212.0 COG0617@1|root,COG0617@2|Bacteria,1MU2X@1224|Proteobacteria,1RPFJ@1236|Gammaproteobacteria,1XHAW@135619|Oceanospirillales 135619|Oceanospirillales J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate cca - 2.7.7.72 ko:K00974 ko03013,map03013 - R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016 - - - HD,PolyA_pol,PolyA_pol_RNAbd k141_17668_1 1284352.AOIG01000010_gene1890 1.43e-14 76.3 COG0506@1|root,COG0506@2|Bacteria,1TQV3@1239|Firmicutes,4HAC1@91061|Bacilli,26RKC@186822|Paenibacillaceae 91061|Bacilli E Proline dehydrogenase fadM - - ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 - R10507 RC00083 ko00000,ko00001,ko01000 - - - Pro_dh k141_17668_2 160860.XP_007338364.1 5.16e-13 68.9 COG1062@1|root,KOG0022@2759|Eukaryota,38BN7@33154|Opisthokonta,3NVMR@4751|Fungi,3UZTE@5204|Basidiomycota,224PX@155619|Agaricomycetes,3H252@355688|Agaricomycetes incertae sedis 4751|Fungi Q Class III ADH enzyme - - 1.1.1.1,1.1.1.284 ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 - R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N k141_24965_1 425104.Ssed_1123 1.94e-50 160.0 2EYVM@1|root,33UJE@2|Bacteria,1NV5D@1224|Proteobacteria,1SNM6@1236|Gammaproteobacteria,2QC2T@267890|Shewanellaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_4817_2 1423321.AS29_05635 8.37e-64 206.0 28XAZ@1|root,2ZJ8Y@2|Bacteria,1V2XT@1239|Firmicutes,4HGD4@91061|Bacilli,1ZG66@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_2425_1 1279017.AQYJ01000028_gene2166 3.11e-204 573.0 COG1253@1|root,COG1253@2|Bacteria,1MWT3@1224|Proteobacteria,1RQBC@1236|Gammaproteobacteria,465JI@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG1253 Hemolysins and related proteins containing CBS domains - - - - - - - - - - - - CBS,DUF21 k141_2425_2 1042377.AFPJ01000024_gene816 2.86e-43 151.0 COG0705@1|root,COG0705@2|Bacteria,1MYPM@1224|Proteobacteria,1RN1K@1236|Gammaproteobacteria,463ZC@72275|Alteromonadaceae 1236|Gammaproteobacteria S membrane protein (homolog of Drosophila rhomboid) glpG GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019219,GO:0019222,GO:0019538,GO:0031224,GO:0031226,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042802,GO:0043170,GO:0043565,GO:0044212,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:0140096,GO:1901363,GO:1901564,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - ko:K02441 - - - - ko00000 - - - NRho,Rhomboid,Rhomboid_N k141_3630_2 1280001.BAOA01000050_gene1375 1.32e-80 249.0 COG1317@1|root,COG1317@2|Bacteria,1MYX8@1224|Proteobacteria,1S872@1236|Gammaproteobacteria,1XUIE@135623|Vibrionales 135623|Vibrionales N COG1317 Flagellar biosynthesis type III secretory pathway protein - - - ko:K02411 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - FliH k141_3630_3 945543.VIBR0546_21620 7.79e-195 546.0 COG1536@1|root,COG1536@2|Bacteria,1MV9X@1224|Proteobacteria,1RM9B@1236|Gammaproteobacteria,1XU8Q@135623|Vibrionales 135623|Vibrionales N Flagellar motor switch protein fliG - - ko:K02410 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02035 - - - FliG_C,FliG_N k141_3630_4 675814.VIC_004726 0.0 881.0 COG1766@1|root,COG1766@2|Bacteria,1MUQR@1224|Proteobacteria,1RN6T@1236|Gammaproteobacteria,1XTK5@135623|Vibrionales 135623|Vibrionales N The M ring may be actively involved in energy transduction - - - ko:K02409 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 - - YscJ_FliF,YscJ_FliF_C k141_3630_5 945543.VIBR0546_21610 7.32e-57 179.0 COG1677@1|root,COG1677@2|Bacteria,1N6TP@1224|Proteobacteria,1SCK1@1236|Gammaproteobacteria,1XXYT@135623|Vibrionales 135623|Vibrionales N Flagellar hook-basal body fliE - - ko:K02408 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FliE k141_3630_6 1280001.BAOA01000050_gene1379 1.17e-145 421.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1XVEB@135623|Vibrionales 135623|Vibrionales T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - - - - - - - - - - HTH_8,Response_reg,Sigma54_activat k141_21448_1 1453501.JELR01000001_gene2055 6.59e-212 596.0 COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,1RMFY@1236|Gammaproteobacteria,464BF@72275|Alteromonadaceae 1236|Gammaproteobacteria J thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence rpsA GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113,GO:2000765,GO:2000766 - ko:K02945 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - S1 k141_85_2 452637.Oter_0623 3.02e-29 110.0 COG3428@1|root,COG3428@2|Bacteria,46VXR@74201|Verrucomicrobia 74201|Verrucomicrobia S Bacterial PH domain - - - ko:K08981 - - - - ko00000 - - - bPH_2 k141_32142_1 935836.JAEL01000190_gene1909 2.04e-10 60.5 COG0686@1|root,COG0686@2|Bacteria,1TNZ5@1239|Firmicutes,4HABX@91061|Bacilli,1ZBQE@1386|Bacillus 91061|Bacilli E Belongs to the AlaDH PNT family ald GO:0000286,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009987,GO:0016054,GO:0016491,GO:0016638,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.4.1.1 ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 - R00396 RC00008 ko00000,ko00001,ko01000 - - - AlaDh_PNT_C,AlaDh_PNT_N k141_32142_2 218284.CCDN010000001_gene376 4.28e-33 124.0 COG1457@1|root,COG1457@2|Bacteria,1V0CC@1239|Firmicutes,4HDNV@91061|Bacilli,1ZCSZ@1386|Bacillus 91061|Bacilli F Permease for cytosine/purines, uracil, thiamine, allantoin - - - ko:K10974 - - - - ko00000,ko02000 2.A.39.1 - - Transp_cyt_pur k141_22669_1 1279017.AQYJ01000028_gene2336 4.87e-78 248.0 COG4579@1|root,COG4579@2|Bacteria,1MVRB@1224|Proteobacteria,1RMC2@1236|Gammaproteobacteria,4655G@72275|Alteromonadaceae 1236|Gammaproteobacteria F Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation aceK GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004721,GO:0005488,GO:0005524,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008772,GO:0009987,GO:0016208,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0017076,GO:0018105,GO:0018193,GO:0018209,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050790,GO:0065007,GO:0065009,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.11.5 ko:K00906 - - - - ko00000,ko01000 - - - AceK k141_16684_1 1453501.JELR01000001_gene1820 1.91e-97 290.0 COG0596@1|root,COG0596@2|Bacteria,1QTWQ@1224|Proteobacteria,1T1JQ@1236|Gammaproteobacteria,46DBF@72275|Alteromonadaceae 1236|Gammaproteobacteria S Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 k141_34543_2 1279017.AQYJ01000028_gene2497 3.1e-31 112.0 COG2914@1|root,COG2914@2|Bacteria,1MZCH@1224|Proteobacteria,1SCHG@1236|Gammaproteobacteria,467WA@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the UPF0125 (RnfH) family rnfH - - ko:K09801 - - - - ko00000 - - - Ub-RnfH k141_19072_1 264203.ZMO1275 8.43e-28 114.0 COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,2TQN9@28211|Alphaproteobacteria,2K130@204457|Sphingomonadales 204457|Sphingomonadales E Threonine dehydratase ilvA - 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - - ACT,PALP k141_3640_1 358681.BBR47_45330 9.68e-64 209.0 COG0583@1|root,COG0583@2|Bacteria,1V2BE@1239|Firmicutes,4HG43@91061|Bacilli,26U87@186822|Paenibacillaceae 91061|Bacilli K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate k141_20257_1 1279017.AQYJ01000027_gene1610 8.98e-169 483.0 COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,1RN6I@1236|Gammaproteobacteria,4654G@72275|Alteromonadaceae 1236|Gammaproteobacteria H Involved in the biosynthesis of porphyrin-containing compound yggW GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - - - - - - - - - - HemN_C,Radical_SAM k141_20257_2 1453501.JELR01000002_gene979 5.35e-108 315.0 COG0127@1|root,COG0127@2|Bacteria,1MUK5@1224|Proteobacteria,1S27C@1236|Gammaproteobacteria,466HT@72275|Alteromonadaceae 1236|Gammaproteobacteria F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions rdgB GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035870,GO:0036220,GO:0036222,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0046983,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 ko:K02428 ko00230,map00230 - R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000 - - iEC55989_1330.EC55989_3247,iECO111_1330.ECO111_3702,iECSE_1348.ECSE_3222,iECW_1372.ECW_m3212,iEKO11_1354.EKO11_0774,iEcE24377_1341.EcE24377A_3298,iWFL_1372.ECW_m3212 Ham1p_like k141_20257_3 1279017.AQYJ01000027_gene1612 1.76e-70 216.0 2DP15@1|root,3303T@2|Bacteria,1N7NN@1224|Proteobacteria,1S90P@1236|Gammaproteobacteria,468AH@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF4426) PP5099 - - - - - - - - - - - DUF4426 k141_20257_6 1453501.JELR01000002_gene983 0.0 1014.0 COG0699@1|root,COG0699@2|Bacteria,1MXBK@1224|Proteobacteria,1RSJC@1236|Gammaproteobacteria,465QM@72275|Alteromonadaceae 1236|Gammaproteobacteria S GTPases (dynamin-related) - - - - - - - - - - - - Dynamin_N k141_20257_8 1453501.JELR01000002_gene985 6.57e-136 391.0 COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,1RNQK@1236|Gammaproteobacteria,466CZ@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline proC GO:0003674,GO:0003824,GO:0004735,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0017144,GO:0018130,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0055114,GO:0055129,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 - - iSBO_1134.SBO_0282,ic_1306.c0493 F420_oxidored,P5CR_dimer k141_20257_9 1453501.JELR01000002_gene986 1.89e-109 321.0 COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,1RNPM@1236|Gammaproteobacteria,466EB@72275|Alteromonadaceae 1236|Gammaproteobacteria S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis yggS - - ko:K06997 - - - - ko00000 - - - Ala_racemase_N k141_7174_2 1453501.JELR01000001_gene3274 9.2e-85 261.0 2BZVX@1|root,32R5V@2|Bacteria,1RKXP@1224|Proteobacteria,1T470@1236|Gammaproteobacteria,468AV@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_22671_1 1307436.PBF_18484 1.25e-73 233.0 COG3807@1|root,COG4990@1|root,COG3807@2|Bacteria,COG4990@2|Bacteria,1V3XE@1239|Firmicutes,4HZA4@91061|Bacilli,1ZEKK@1386|Bacillus 91061|Bacilli T Peptidase_C39 like family - - - - - - - - - - - - Peptidase_C39_2,SH3_3,SLH k141_28610_1 59538.XP_005979070.1 2.4e-57 189.0 COG4948@1|root,2QRKX@2759|Eukaryota,38HCT@33154|Opisthokonta,3BYW6@33208|Metazoa 33208|Metazoa M Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - 4.2.1.90 ko:K12661 ko00051,ko01120,map00051,map01120 - R03774 RC00543 ko00000,ko00001,ko01000 - - - MR_MLE_C,MR_MLE_N k141_17918_1 1116375.VEJY3_06715 3.09e-41 136.0 2AWDU@1|root,31N9U@2|Bacteria,1QK0Z@1224|Proteobacteria,1TI3H@1236|Gammaproteobacteria,1XYAK@135623|Vibrionales 135623|Vibrionales S Pas factor saposin fold - - - - - - - - - - - - Pas_Saposin k141_17918_2 324057.Pjdr2_6136 2.43e-23 101.0 COG0277@1|root,COG0277@2|Bacteria,1TPBC@1239|Firmicutes,4H9UU@91061|Bacilli,26UJU@186822|Paenibacillaceae 91061|Bacilli C FAD linked oxidases, C-terminal domain - - - - - - - - - - - - FAD-oxidase_C,FAD_binding_4 k141_3641_1 218284.CCDN010000002_gene1990 7.94e-11 61.2 COG0150@1|root,COG0150@2|Bacteria,1TP9J@1239|Firmicutes,4HABW@91061|Bacilli,1ZBPS@1386|Bacillus 91061|Bacilli F Phosphoribosylformylglycinamidine cyclo-ligase purM - 6.3.3.1 ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04208 RC01100 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C k141_3641_2 218284.CCDN010000002_gene1991 6.92e-106 307.0 COG0299@1|root,COG0299@2|Bacteria,1V3RJ@1239|Firmicutes,4HGY5@91061|Bacilli,1ZFSE@1386|Bacillus 91061|Bacilli F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate purN - 2.1.2.2 ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04325,R04326 RC00026,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 - - - Formyl_trans_N k141_16685_1 42565.FP66_14645 3.15e-62 200.0 COG1168@1|root,COG1168@2|Bacteria,1MY33@1224|Proteobacteria,1RP58@1236|Gammaproteobacteria,1XIU6@135619|Oceanospirillales 135619|Oceanospirillales E Aminotransferase - - 4.4.1.8 ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 - R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 k141_16685_2 1492922.GY26_15510 6.8e-52 168.0 2DVWY@1|root,33XI0@2|Bacteria,1NWZ9@1224|Proteobacteria,1SP11@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_28611_1 1408422.JHYF01000013_gene549 7.99e-05 49.3 COG1075@1|root,COG1075@2|Bacteria,1TQFF@1239|Firmicutes 1239|Firmicutes S acetyltransferases and hydrolases with the alpha beta hydrolase fold lipA1 - 3.1.1.3 ko:K01046 ko00561,ko01100,map00561,map01100 M00098 R02250,R02687 RC00020,RC00037,RC00041,RC00094 ko00000,ko00001,ko00002,ko01000 - - - DUF676,PGAP1 k141_7175_1 573.JG24_15545 4.52e-91 281.0 COG2308@1|root,COG2308@2|Bacteria,1MUAD@1224|Proteobacteria,1RNAF@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Circularly permuted ATP-grasp type 2 IV02_06045 - - - - - - - - - - - CP_ATPgrasp_2 k141_35731_1 697281.Mahau_0968 1.06e-13 77.8 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,42F44@68295|Thermoanaerobacterales 186801|Clostridia V ABC transporter, transmembrane region - - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran k141_14337_2 218284.CCDN010000002_gene2617 6.76e-38 132.0 COG1595@1|root,COG1595@2|Bacteria,1V9ZH@1239|Firmicutes,4HGNB@91061|Bacilli,1ZGEX@1386|Bacillus 91061|Bacilli K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_27377_1 1294265.JCM21738_1732 1.01e-124 380.0 COG2352@1|root,COG2352@2|Bacteria,1TQB6@1239|Firmicutes,4HCAF@91061|Bacilli,1ZAYH@1386|Bacillus 91061|Bacilli C Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle ppc GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464 4.1.1.31 ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 M00168,M00170,M00171,M00172,M00173,M00346,M00374 R00345 RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPcase k141_6010_1 866895.HBHAL_5004 4.99e-58 192.0 COG2211@1|root,COG2211@2|Bacteria,1UIKR@1239|Firmicutes,4ISMM@91061|Bacilli,3NEVK@45667|Halobacillus 91061|Bacilli G Transmembrane secretion effector - - - - - - - - - - - - MFS_1 k141_22672_1 1453501.JELR01000001_gene2019 2.93e-168 478.0 COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,1RQRP@1236|Gammaproteobacteria,4653Y@72275|Alteromonadaceae 1236|Gammaproteobacteria Q COG1228 Imidazolonepropionase and related amidohydrolases - - - - - - - - - - - - Amidohydro_1 k141_32145_2 42565.FP66_09345 8.17e-55 171.0 COG4327@1|root,COG4327@2|Bacteria,1N0TK@1224|Proteobacteria,1S8V9@1236|Gammaproteobacteria,1XKHT@135619|Oceanospirillales 135619|Oceanospirillales S membrane - - - - - - - - - - - - DUF4212 k141_21483_1 42565.FP66_05495 2.09e-106 325.0 COG0365@1|root,COG0365@2|Bacteria,1MUX7@1224|Proteobacteria,1RPGT@1236|Gammaproteobacteria,1XI6C@135619|Oceanospirillales 135619|Oceanospirillales I acetoacetyl-CoA - - 6.2.1.16 ko:K01907 ko00280,ko00650,map00280,map00650 - R01357 RC00004,RC00014 ko00000,ko00001,ko01000,ko01004 - - - ACAS_N,AMP-binding,AMP-binding_C k141_11941_1 1121938.AUDY01000009_gene2321 1.48e-151 441.0 COG0591@1|root,COG0591@2|Bacteria,1TQCK@1239|Firmicutes,4HB5K@91061|Bacilli 91061|Bacilli E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - ko:K03307 - - - - ko00000 2.A.21 - - SSF k141_26228_1 42565.FP66_06605 9.06e-76 226.0 COG0099@1|root,COG0099@2|Bacteria,1RD1G@1224|Proteobacteria,1S3NX@1236|Gammaproteobacteria,1XJXT@135619|Oceanospirillales 135619|Oceanospirillales J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits rpsM - - ko:K02952 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S13 k141_22673_1 218284.CCDN010000006_gene3672 6.43e-131 381.0 COG2873@1|root,COG2873@2|Bacteria,1VYCY@1239|Firmicutes,4H9X5@91061|Bacilli,1ZS2F@1386|Bacillus 91061|Bacilli E O-acetylhomoserine metY - 2.5.1.49 ko:K01740 ko00270,ko01100,map00270,map01100 - R01287,R04859 RC00020,RC02821,RC02848 ko00000,ko00001,ko01000 - - - CoA_binding_2,Cys_Met_Meta_PP k141_23823_1 1294265.JCM21738_4044 9.93e-94 277.0 COG1589@1|root,COG1589@2|Bacteria,1V6V5@1239|Firmicutes,4HDFD@91061|Bacilli,1ZDSW@1386|Bacillus 91061|Bacilli D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex divIB - - ko:K03589 ko04112,map04112 - - - ko00000,ko00001,ko03036 - - - FtsQ,POTRA_1 k141_23823_2 1294265.JCM21738_4045 3.29e-133 382.0 COG3879@1|root,COG3879@2|Bacteria,1V0FG@1239|Firmicutes,4HAN4@91061|Bacilli,1ZE4Z@1386|Bacillus 91061|Bacilli S protein conserved in bacteria ylxW GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - - - - - - - - - - DUF881 k141_19075_1 1356852.N008_01840 3.76e-10 61.2 COG5520@1|root,COG5520@2|Bacteria,4NF4C@976|Bacteroidetes,47UI1@768503|Cytophagia 976|Bacteroidetes G Glycosyl hydrolase family 30 beta sandwich domain - - 3.2.1.45 ko:K01201 ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142 - R01498 RC00059,RC00451 ko00000,ko00001,ko01000 - GH30 - Glyco_hydro_30,Glyco_hydro_30C k141_3643_1 935837.JAEK01000030_gene2706 2.87e-80 244.0 COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,4HA7D@91061|Bacilli,1ZARN@1386|Bacillus 91061|Bacilli T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - ko:K02483 - - - - ko00000,ko02022 - - - Response_reg,Trans_reg_C k141_17921_2 1051646.VITU9109_15898 4.56e-35 128.0 COG1172@1|root,COG1172@2|Bacteria,1MX7D@1224|Proteobacteria,1TCBA@1236|Gammaproteobacteria,1Y04D@135623|Vibrionales 135623|Vibrionales G Branched-chain amino acid transport system / permease component - - - ko:K10440 ko02010,map02010 M00212 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - BPD_transp_2 k141_29772_1 218284.CCDN010000001_gene760 4.76e-177 508.0 COG0358@1|root,COG0358@2|Bacteria,1TQ0X@1239|Firmicutes,4HAG2@91061|Bacilli,1ZC16@1386|Bacillus 91061|Bacilli L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG - - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2 k141_32146_1 218284.CCDN010000002_gene2179 7.17e-120 348.0 COG1300@1|root,COG1300@2|Bacteria,1U15U@1239|Firmicutes,4HEDT@91061|Bacilli,1ZDAQ@1386|Bacillus 91061|Bacilli S Stage II sporulation protein M - - - - - - - - - - - - SpoIIM k141_34545_1 1117647.M5M_18335 8.28e-280 772.0 COG0665@1|root,COG0665@2|Bacteria,1MU40@1224|Proteobacteria,1RMJY@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Tryptophan halogenase - - 1.14.19.9 ko:K14266 ko00404,ko01130,map00404,map01130 M00789,M00790 R09570 RC00949 ko00000,ko00001,ko00002,ko01000 - - - Trp_halogenase k141_7177_2 1042377.AFPJ01000029_gene561 0.00042 42.0 COG0764@1|root,COG0764@2|Bacteria,1MWV8@1224|Proteobacteria,1RP6W@1236|Gammaproteobacteria,4657R@72275|Alteromonadaceae 1236|Gammaproteobacteria I Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length fabA - 4.2.1.59,5.3.3.14 ko:K01716 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00083 R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07639 RC00831,RC01078,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FabA k141_6012_1 1231057.AMGD01000030_gene1775 1.02e-87 265.0 COG0697@1|root,COG0697@2|Bacteria,1TRH8@1239|Firmicutes,4HD2Z@91061|Bacilli,26CZM@186818|Planococcaceae 91061|Bacilli EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - - - - - - - - - - EamA k141_30988_1 997296.PB1_06792 7.41e-12 64.7 COG1623@1|root,COG1623@2|Bacteria,1TQD8@1239|Firmicutes,4HAQP@91061|Bacilli,1ZBIY@1386|Bacillus 91061|Bacilli L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation disA - 2.7.7.85 ko:K07067 - - - - ko00000,ko01000 - - - DisA-linker,DisA_N,HHH,HHH_2 k141_30988_2 1294265.JCM21738_4608 3.57e-167 473.0 COG4956@1|root,COG4956@2|Bacteria,1TP0P@1239|Firmicutes,4H9NQ@91061|Bacilli,1ZB5A@1386|Bacillus 91061|Bacilli S COG4956 Integral membrane protein (PIN domain superfamily) yacL GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - - - - - - - - - - TRAM k141_11942_1 1453501.JELR01000005_gene1577 1.08e-127 390.0 COG1629@1|root,COG1629@2|Bacteria,1MV8W@1224|Proteobacteria,1RQEQ@1236|Gammaproteobacteria,46A77@72275|Alteromonadaceae 1236|Gammaproteobacteria P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec k141_27386_2 1116375.VEJY3_20401 4.68e-172 483.0 COG0543@1|root,COG0543@2|Bacteria,1R6QZ@1224|Proteobacteria,1RNK9@1236|Gammaproteobacteria,1XV1V@135623|Vibrionales 135623|Vibrionales C Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B asrB - - - - - - - - - - - DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1 k141_2477_1 1142394.PSMK_25190 5.6e-61 202.0 COG0160@1|root,COG0160@2|Bacteria,2IYBU@203682|Planctomycetes 203682|Planctomycetes H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - - - - - - - - - - Aminotran_3 k141_25014_1 1034347.CAHJ01000039_gene4684 1.65e-116 350.0 COG0481@1|root,COG0481@2|Bacteria,1TP0G@1239|Firmicutes,4HASA@91061|Bacilli,1ZC7J@1386|Bacillus 91061|Bacilli M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner lepA - - ko:K03596 ko05134,map05134 - - - ko00000,ko00001 - - - EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C k141_14352_2 1308866.J416_14337 9.58e-48 164.0 COG0477@1|root,COG2814@2|Bacteria,1TQEW@1239|Firmicutes,4HASU@91061|Bacilli,4709N@74385|Gracilibacillus 91061|Bacilli EGP Transmembrane secretion effector ymfD - - ko:K08221 - - - - ko00000,ko02000 2.A.1.32 - - MFS_1,MFS_2,Sugar_tr k141_3656_1 218284.CCDN010000002_gene2392 2.09e-70 219.0 COG1309@1|root,COG1309@2|Bacteria,1VDNV@1239|Firmicutes,4HKG8@91061|Bacilli,1ZI66@1386|Bacillus 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - TetR_C_6,TetR_N k141_28619_1 218284.CCDN010000001_gene1483 2.24e-115 344.0 COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HACS@91061|Bacilli,1ZATG@1386|Bacillus 91061|Bacilli IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - 6.2.1.3 ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding,AMP-binding_C k141_2478_1 218284.CCDN010000002_gene2218 1.51e-97 284.0 COG1959@1|root,COG1959@2|Bacteria,1V4G2@1239|Firmicutes,4HHBH@91061|Bacilli,1ZH5D@1386|Bacillus 91061|Bacilli K Transcriptional regulator nsrR - - ko:K13771 ko05132,map05132 - - - ko00000,ko00001,ko03000 - - - Rrf2 k141_7187_1 411483.FAEPRAA2165_03404 4.11e-19 87.0 COG0863@1|root,COG0863@2|Bacteria,1TRDZ@1239|Firmicutes,249ZT@186801|Clostridia,3WKGI@541000|Ruminococcaceae 186801|Clostridia L Belongs to the N(4) N(6)-methyltransferase family - - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k141_26237_1 1307436.PBF_13084 1.32e-72 221.0 COG0824@1|root,COG0824@2|Bacteria,1V6GS@1239|Firmicutes,4HJ05@91061|Bacilli,1ZH3F@1386|Bacillus 91061|Bacilli S thioesterase ysmA - - ko:K07107 - - - - ko00000,ko01000 - - - 4HBT,4HBT_2 k141_10752_1 1397696.KK211189_gene1826 7.16e-20 91.3 COG0596@1|root,COG0596@2|Bacteria,1UEQR@1239|Firmicutes,4HCS0@91061|Bacilli 91061|Bacilli S Alpha beta hydrolase - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 k141_29781_2 1042377.AFPJ01000028_gene2206 1.44e-114 333.0 COG0745@1|root,COG0745@2|Bacteria,1MYNB@1224|Proteobacteria,1S77Z@1236|Gammaproteobacteria,46AXP@72275|Alteromonadaceae 1236|Gammaproteobacteria T Transcriptional regulatory protein, C terminal - - - - - - - - - - - - Response_reg,Trans_reg_C k141_29781_3 1042377.AFPJ01000028_gene2207 2.37e-171 487.0 COG5002@1|root,COG5002@2|Bacteria,1NWB7@1224|Proteobacteria,1SPHN@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Sensory histidine kinase in two-component regulatory system with RstA - - 2.7.13.3 ko:K02484,ko:K07639,ko:K18143 ko01501,ko02020,map01501,map02020 M00446,M00649,M00655 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 - - - HATPase_c,HisKA k141_3657_1 1172185.KB911516_gene2554 4.04e-36 136.0 COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4FVYU@85025|Nocardiaceae 201174|Actinobacteria C Belongs to the aldehyde dehydrogenase family - - 1.2.1.3 ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh,LpxK k141_21491_1 986075.CathTA2_0801 7.3e-107 323.0 COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,4H9VK@91061|Bacilli 91061|Bacilli G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system - - 3.6.3.17 ko:K02056 - M00221 - - ko00000,ko00002,ko01000,ko02000 3.A.1.2 - - ABC_tran k141_19085_1 1552758.NC00_09625 6.08e-10 64.7 COG1426@1|root,COG1426@2|Bacteria,1N240@1224|Proteobacteria,1RQMV@1236|Gammaproteobacteria,1X5X4@135614|Xanthomonadales 135614|Xanthomonadales S protein conserved in bacteria - - - ko:K15539 - - - - ko00000 - - - DUF4115,HTH_25 k141_26238_1 502025.Hoch_4973 6.17e-34 129.0 COG0415@1|root,COG0415@2|Bacteria,1RG4D@1224|Proteobacteria,42NWP@68525|delta/epsilon subdivisions,2WJUA@28221|Deltaproteobacteria,2YUE6@29|Myxococcales 28221|Deltaproteobacteria L Deoxyribodipyrimidine photo-lyase phr - 4.1.99.3 ko:K01669 - - - - ko00000,ko01000,ko03400 - - - DNA_photolyase,FAD_binding_7 k141_17933_1 1294265.JCM21738_1075 4.47e-182 519.0 COG3276@1|root,COG3276@2|Bacteria,1TPQS@1239|Firmicutes,4HDD5@91061|Bacilli,1ZD2K@1386|Bacillus 91061|Bacilli J Selenocysteine-specific translation elongation factor selB - - ko:K03833 - - - - ko00000,ko03012 - - - GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3 k141_21676_2 754436.JCM19237_568 1.22e-101 298.0 2AZXR@1|root,31S7H@2|Bacteria,1QJA3@1224|Proteobacteria,1TH8S@1236|Gammaproteobacteria,1XSIN@135623|Vibrionales 135623|Vibrionales S Outer membrane protein beta-barrel domain - - - - - - - - - - - - OMP_b-brl k141_32247_1 1279017.AQYJ01000029_gene3451 1.9e-195 564.0 COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,1RMT5@1236|Gammaproteobacteria,4643B@72275|Alteromonadaceae 1236|Gammaproteobacteria O peptidylprolyl isomerase ppiD GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0008150,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031233,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0061077,GO:0071575,GO:0071944,GO:0098552 5.2.1.8 ko:K03770 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_2,Rotamase_3,SurA_N_3 k141_16875_1 1453501.JELR01000002_gene1017 9.03e-07 49.7 COG0492@1|root,COG0492@2|Bacteria,1MVWS@1224|Proteobacteria,1RRRH@1236|Gammaproteobacteria,469YY@72275|Alteromonadaceae 1236|Gammaproteobacteria O FAD binding domain - - - - - - - - - - - - Pyr_redox_2 k141_16875_2 1453501.JELR01000002_gene1015 7.84e-142 404.0 COG1040@1|root,COG1040@2|Bacteria,1QV41@1224|Proteobacteria,1RSAP@1236|Gammaproteobacteria,4651C@72275|Alteromonadaceae 1236|Gammaproteobacteria S competence protein - - - - - - - - - - - - - k141_340_1 1279017.AQYJ01000029_gene3375 2.19e-06 49.3 COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,1RMY5@1236|Gammaproteobacteria,4649T@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG1138 Cytochrome c biogenesis factor ccmF GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0019538,GO:0020037,GO:0022607,GO:0031224,GO:0031226,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046906,GO:0048037,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564 - ko:K02198 - - - - ko00000,ko02000 9.B.14.1 - - CcmF_C,Cytochrom_C_asm k141_340_2 742823.HMPREF9465_01941 6.16e-43 149.0 COG0526@1|root,COG0526@2|Bacteria,1RI3N@1224|Proteobacteria,2VR8D@28216|Betaproteobacteria,4PQXI@995019|Sutterellaceae 28216|Betaproteobacteria CO Thioredoxin-like dsbE - - ko:K02199 - - - - ko00000,ko03110 - - - AhpC-TSA,Redoxin k141_340_3 1042377.AFPJ01000036_gene1247 2.42e-93 277.0 COG1739@1|root,COG1739@2|Bacteria,1NFJC@1224|Proteobacteria,1RPBF@1236|Gammaproteobacteria,4672X@72275|Alteromonadaceae 1236|Gammaproteobacteria S Uncharacterized protein family UPF0029 yigZ - 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 - - - DUF1949,UPF0029 k141_340_4 1279017.AQYJ01000026_gene246 6.23e-182 515.0 COG2050@1|root,COG2050@2|Bacteria,1RF3N@1224|Proteobacteria,1S82J@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q Thioesterase - - - - - - - - - - - - 4HBT k141_1392_1 218284.CCDN010000005_gene3459 6.16e-89 271.0 COG1168@1|root,COG1168@2|Bacteria,1TP5G@1239|Firmicutes,4H9PE@91061|Bacilli,1ZCQC@1386|Bacillus 91061|Bacilli E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities patB - 4.4.1.8 ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 - R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 k141_20374_1 1042377.AFPJ01000004_gene391 1.08e-257 717.0 COG3046@1|root,COG3046@2|Bacteria,1MUHX@1224|Proteobacteria,1RNUM@1236|Gammaproteobacteria,465DZ@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein related to deoxyribodipyrimidine photolyase - - - ko:K06876 - - - - ko00000 - - - DPRP k141_7385_1 674977.VMC_30710 8.31e-165 473.0 COG0144@1|root,COG3270@1|root,COG0144@2|Bacteria,COG3270@2|Bacteria,1NAY1@1224|Proteobacteria,1RP74@1236|Gammaproteobacteria,1XSE4@135623|Vibrionales 135623|Vibrionales J Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA rsmF GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.178 ko:K11392 - - - - ko00000,ko01000,ko03009 - - - Methyltr_RsmB-F,Methyltr_RsmF_N,Methyltranf_PUA k141_28826_2 218284.CCDN010000004_gene3037 1.11e-39 134.0 COG0736@1|root,COG0736@2|Bacteria,1VA0T@1239|Firmicutes,4HKBI@91061|Bacilli,1ZI02@1386|Bacillus 91061|Bacilli I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein acpS - 2.7.8.7 ko:K00997 ko00770,map00770 - R01625 RC00002 ko00000,ko00001,ko01000 - - iYO844.BSU04620 ACPS k141_34705_1 1042377.AFPJ01000009_gene259 2.62e-88 266.0 COG0742@1|root,COG0742@2|Bacteria,1MX8Z@1224|Proteobacteria,1RMIB@1236|Gammaproteobacteria,466ZU@72275|Alteromonadaceae 1236|Gammaproteobacteria J Specifically methylates the guanosine in position 1516 of 16S rRNA rsmJ GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036308,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.242 ko:K15984 - - - - ko00000,ko01000,ko03009 - - - SAM_MT k141_15719_1 1042377.AFPJ01000016_gene144 6.4e-227 635.0 COG0008@1|root,COG0008@2|Bacteria,1MUC8@1224|Proteobacteria,1RQ7G@1236|Gammaproteobacteria,464TJ@72275|Alteromonadaceae 1236|Gammaproteobacteria J COG0008 Glutamyl- and glutaminyl-tRNA synthetases glnS GO:0003674,GO:0003824,GO:0004812,GO:0004819,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006425,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.18 ko:K01886 ko00970,ko01100,map00970,map01100 M00359,M00360 R03652 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iECIAI39_1322.ECIAI39_0637 tRNA-synt_1c,tRNA-synt_1c_C k141_37046_1 1279017.AQYJ01000029_gene3402 3.89e-69 215.0 COG3088@1|root,COG3088@2|Bacteria,1MZZ5@1224|Proteobacteria,1S9DV@1236|Gammaproteobacteria,467TB@72275|Alteromonadaceae 1236|Gammaproteobacteria P subunit of a heme lyase ccmH GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015035,GO:0015036,GO:0016020,GO:0016043,GO:0016491,GO:0016667,GO:0017004,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0055114,GO:0065003,GO:0071840,GO:0071944,GO:0098552,GO:0098567 - ko:K02200,ko:K04017 - - - - ko00000 - - - CcmH k141_10911_1 395493.BegalDRAFT_1468 4.25e-25 107.0 2D784@1|root,32TNH@2|Bacteria,1N098@1224|Proteobacteria,1SDM3@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_12181_1 1116375.VEJY3_21386 4.95e-75 228.0 COG2249@1|root,COG2249@2|Bacteria,1R49E@1224|Proteobacteria,1RZBC@1236|Gammaproteobacteria 1236|Gammaproteobacteria S NADPH-quinone reductase (modulator of drug activity B) - - - ko:K11746 - - - - ko00000,ko02000 2.A.37.1.1 - - Flavodoxin_2 k141_12181_2 1116375.VEJY3_21391 2.97e-108 312.0 COG1917@1|root,COG1917@2|Bacteria,1RH1V@1224|Proteobacteria,1SY88@1236|Gammaproteobacteria,1XZPY@135623|Vibrionales 135623|Vibrionales S Cupin domain - - - - - - - - - - - - Cupin_2 k141_12181_3 1116375.VEJY3_21396 2.38e-143 407.0 COG0599@1|root,COG0599@2|Bacteria,1QTZH@1224|Proteobacteria,1SY81@1236|Gammaproteobacteria,1Y0BI@135623|Vibrionales 135623|Vibrionales S Carboxymuconolactone decarboxylase family - - - - - - - - - - - - CMD k141_12181_4 1116375.VEJY3_21401 1.48e-71 218.0 COG4925@1|root,COG4925@2|Bacteria,1N8YU@1224|Proteobacteria,1SDSQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria I sulfurtransferase activity - - - - - - - - - - - - Cyclophil_like k141_12181_5 1116375.VEJY3_21406 9.34e-08 52.4 COG1168@1|root,COG1168@2|Bacteria,1MY33@1224|Proteobacteria,1RP58@1236|Gammaproteobacteria,1XUW6@135623|Vibrionales 135623|Vibrionales E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities - - 4.4.1.8 ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 - R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 k141_7386_1 1461580.CCAS010000003_gene450 8.67e-58 189.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4HASW@91061|Bacilli,1ZB29@1386|Bacillus 91061|Bacilli I Belongs to the thiolase family - - 2.3.1.16,2.3.1.9 ko:K00626,ko:K00632 ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00087,M00088,M00095,M00113,M00373,M00374,M00375 R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095 RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N k141_21677_1 218284.CCDN010000007_gene3792 3.32e-11 62.4 COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,4H9MW@91061|Bacilli,1ZBKI@1386|Bacillus 91061|Bacilli L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids dnaA GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - ko:K02313 ko02020,ko04112,map02020,map04112 - - - ko00000,ko00001,ko03032,ko03036 - - - Bac_DnaA,Bac_DnaA_C,DnaA_N k141_6307_1 1042377.AFPJ01000028_gene2192 2.13e-94 282.0 2C3WA@1|root,2Z8P1@2|Bacteria,1R8VC@1224|Proteobacteria,1S5UD@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_6307_2 1453501.JELR01000002_gene1299 5.02e-68 206.0 COG2824@1|root,COG2824@2|Bacteria,1RGUU@1224|Proteobacteria,1S60W@1236|Gammaproteobacteria,467AU@72275|Alteromonadaceae 1236|Gammaproteobacteria P Zn-ribbon-containing protein involved in phosphonate metabolism phnA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K06193 ko01120,map01120 - - - ko00000 - - - PhnA,PhnA_Zn_Ribbon k141_37047_1 1294265.JCM21738_1478 7.13e-130 390.0 COG1048@1|root,COG1048@2|Bacteria,1VTMM@1239|Firmicutes,4HB5N@91061|Bacilli,1ZART@1386|Bacillus 91061|Bacilli C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate citB GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0043937,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0050789,GO:0050793,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0065007,GO:0071704,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS06730 Aconitase,Aconitase_C k141_33503_1 42565.FP66_07955 4.18e-197 563.0 COG1199@1|root,COG1199@2|Bacteria,1MVCU@1224|Proteobacteria,1RMNX@1236|Gammaproteobacteria,1XIVR@135619|Oceanospirillales 135619|Oceanospirillales KL helicase dinG - 3.6.4.12 ko:K03722 - - - - ko00000,ko01000,ko03400 - - - DEAD,DEAD_2,Helicase_C_2,ResIII k141_10912_1 1026970.XP_008834168.1 3.15e-18 87.0 COG0151@1|root,COG0299@1|root,KOG0237@2759|Eukaryota,KOG3076@2759|Eukaryota,38BPB@33154|Opisthokonta,3BDXA@33208|Metazoa,3CXAA@33213|Bilateria,4819S@7711|Chordata,48WR7@7742|Vertebrata,3JB9Y@40674|Mammalia,35IPU@314146|Euarchontoglires,4PT9U@9989|Rodentia 33208|Metazoa F Trifunctional purine biosynthetic protein adenosine-3 GART GO:0001505,GO:0003674,GO:0003824,GO:0004637,GO:0004641,GO:0004644,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006144,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006520,GO:0006544,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006760,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009069,GO:0009108,GO:0009112,GO:0009113,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009396,GO:0009987,GO:0010033,GO:0010035,GO:0016053,GO:0016740,GO:0016741,GO:0016742,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0034641,GO:0034654,GO:0042133,GO:0042221,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046040,GO:0046112,GO:0046148,GO:0046390,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0065007,GO:0065008,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.1.2.2,6.3.3.1,6.3.4.13 ko:K11787 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R04144,R04208,R04325,R04326 RC00026,RC00090,RC00166,RC00197,RC01100,RC01128 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C,Formyl_trans_N,GARS_A,GARS_C,GARS_N k141_10912_2 315750.BPUM_0604 9.33e-20 87.4 COG0150@1|root,COG0150@2|Bacteria,1TP9J@1239|Firmicutes,4HABW@91061|Bacilli,1ZBPS@1386|Bacillus 91061|Bacilli F Phosphoribosylformylglycinamidine cyclo-ligase purM - 6.3.3.1 ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04208 RC01100 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C k141_29903_1 1397527.Q670_03985 6.02e-55 176.0 COG5331@1|root,COG5331@2|Bacteria,1N0MD@1224|Proteobacteria,1SACM@1236|Gammaproteobacteria 1236|Gammaproteobacteria S MAPEG family - - - - - - - - - - - - MAPEG k141_29903_2 1279017.AQYJ01000029_gene3396 1.25e-46 155.0 2CHH4@1|root,32SC0@2|Bacteria,1NPE4@1224|Proteobacteria 1224|Proteobacteria S Bacterial PH domain - - - - - - - - - - - - bPH_5 k141_26485_1 641491.DND132_2354 2.2e-54 183.0 COG0213@1|root,COG0213@2|Bacteria,1MV3H@1224|Proteobacteria,42PCD@68525|delta/epsilon subdivisions,2WKGQ@28221|Deltaproteobacteria,2M9C0@213115|Desulfovibrionales 28221|Deltaproteobacteria F The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis pdp - 2.4.2.2,2.4.2.4 ko:K00756,ko:K00758 ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219 - R01570,R01876,R02296,R02484,R08222,R08230 RC00063 ko00000,ko00001,ko01000 - - - Glycos_trans_3N,Glycos_transf_3,PYNP_C k141_8584_1 218284.CCDN010000007_gene3842 1.28e-100 292.0 COG4682@1|root,COG4682@2|Bacteria,1V29F@1239|Firmicutes,4HG11@91061|Bacilli,1ZFTC@1386|Bacillus 91061|Bacilli S yiaA/B two helix domain - - - - - - - - - - - - YiaAB k141_9738_1 935836.JAEL01000021_gene1537 1.52e-30 128.0 COG2866@1|root,COG2866@2|Bacteria,1TSF6@1239|Firmicutes,4HDT5@91061|Bacilli,1ZBGR@1386|Bacillus 91061|Bacilli E Zinc carboxypeptidase - - - - - - - - - - - - Peptidase_M14 k141_2673_1 1453501.JELR01000005_gene1596 6.7e-202 578.0 COG0366@1|root,COG0366@2|Bacteria,1NUIZ@1224|Proteobacteria,1RPMQ@1236|Gammaproteobacteria,465DG@72275|Alteromonadaceae 1236|Gammaproteobacteria G Alpha amylase, catalytic domain - - 2.4.1.19 ko:K00701 ko00500,map00500 - R11260 - ko00000,ko00001,ko01000 - CBM20,GH13 - Alpha-amylase k141_6323_2 1453501.JELR01000002_gene1296 0.000115 45.1 2AFX8@1|root,3160N@2|Bacteria,1QE3Z@1224|Proteobacteria,1TAFT@1236|Gammaproteobacteria,4691A@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF4124) - - - - - - - - - - - - DUF4124 k141_16920_1 1267533.KB906741_gene510 2.11e-11 67.4 COG3832@1|root,COG3832@2|Bacteria,3Y7RQ@57723|Acidobacteria 57723|Acidobacteria S Activator of Hsp90 ATPase homolog 1-like protein - - - - - - - - - - - - AHSA1 k141_8585_1 218284.CCDN010000006_gene3768 1.56e-105 313.0 COG4191@1|root,COG4191@2|Bacteria,1TRYP@1239|Firmicutes,4HE85@91061|Bacilli,1ZBXM@1386|Bacillus 91061|Bacilli T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,HisK_N k141_32262_1 1487923.DP73_10845 2.72e-05 47.8 COG0755@1|root,COG0755@2|Bacteria,1V4A6@1239|Firmicutes,24IWH@186801|Clostridia,264K0@186807|Peptococcaceae 186801|Clostridia O Cytochrome c assembly protein - - - ko:K02195 ko02010,map02010 M00259 - - ko00000,ko00001,ko00002,ko02000 3.A.1.107 - - Cytochrom_C_asm k141_32262_2 94624.Bpet4070 2.26e-16 80.9 COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,2VHUE@28216|Betaproteobacteria,3T2WJ@506|Alcaligenaceae 28216|Betaproteobacteria O cytochrome c biogenesis ccmF - - ko:K02198 - - - - ko00000,ko02000 9.B.14.1 - - CcmF_C,Cytochrom_C_asm k141_27539_2 1294265.JCM21738_2676 8.41e-23 94.0 2EEB8@1|root,3385J@2|Bacteria,1VM15@1239|Firmicutes,4HPJI@91061|Bacilli,1ZJ91@1386|Bacillus 91061|Bacilli S Spore germination protein GerPE gerPE - - ko:K06303 - - - - ko00000 - - - GerPE k141_21683_1 218284.CCDN010000001_gene1587 3.63e-60 193.0 COG0791@1|root,COG0791@2|Bacteria,1TSZ0@1239|Firmicutes,4HBUM@91061|Bacilli,1ZD7T@1386|Bacillus 91061|Bacilli M COG0791 Cell wall-associated hydrolases (invasion-associated proteins) ykfC - 3.4.14.13 ko:K20742 - - - - ko00000,ko01000,ko01002 - - - NLPC_P60 k141_21683_2 935836.JAEL01000003_gene378 6.3e-55 181.0 COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,4H9YB@91061|Bacilli,1ZBA4@1386|Bacillus 91061|Bacilli E Belongs to the ABC transporter superfamily ykfD - - ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY k141_4978_1 1132442.KB889753_gene129 1.57e-119 360.0 COG0665@1|root,COG0723@1|root,COG0665@2|Bacteria,COG0723@2|Bacteria,1TR1R@1239|Firmicutes,4H9V8@91061|Bacilli,1ZC19@1386|Bacillus 91061|Bacilli CE COG0665 Glycine D-amino acid oxidases (deaminating) yhfW GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0044424,GO:0044464,GO:0055114 - - - - - - - - - - DAO,Rieske k141_15733_1 1042377.AFPJ01000007_gene1844 1.78e-183 526.0 COG3291@1|root,COG3291@2|Bacteria,1QU15@1224|Proteobacteria,1T1KN@1236|Gammaproteobacteria,46D2W@72275|Alteromonadaceae 1236|Gammaproteobacteria S Pkd domain containing protein - - - - - - - - - - - - - k141_29923_1 42565.FP66_10500 1.77e-171 491.0 COG1292@1|root,COG1292@2|Bacteria,1MV0K@1224|Proteobacteria,1RP3E@1236|Gammaproteobacteria,1XHUS@135619|Oceanospirillales 135619|Oceanospirillales M Belongs to the BCCT transporter (TC 2.A.15) family - - - ko:K03451 - - - - ko00000 2.A.15 - - BCCT k141_25230_1 1384056.N787_09855 6.45e-23 98.6 COG1566@1|root,COG1566@2|Bacteria,1RJ3I@1224|Proteobacteria,1S7BS@1236|Gammaproteobacteria,1X4Y6@135614|Xanthomonadales 135614|Xanthomonadales V Protein of unknown function (DUF3667) - - - - - - - - - - - - DUF3667 k141_25230_4 1042377.AFPJ01000043_gene930 2.56e-69 211.0 COG0818@1|root,COG0818@2|Bacteria,1MZ3Q@1224|Proteobacteria,1S92I@1236|Gammaproteobacteria,467RV@72275|Alteromonadaceae 1236|Gammaproteobacteria M Recycling of diacylglycerol produced during the turnover of membrane phospholipid dgkA - 2.7.1.107 ko:K00901 ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231 - R02240 RC00002,RC00017 ko00000,ko00001,ko01000 - - - DAGK_prokar k141_25230_5 1042377.AFPJ01000043_gene931 0.0 1043.0 COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,1RMQI@1236|Gammaproteobacteria,464VE@72275|Alteromonadaceae 1236|Gammaproteobacteria K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth rpoD GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043254,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 k141_25230_6 1042377.AFPJ01000043_gene932 2.55e-32 130.0 COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,1RMGA@1236|Gammaproteobacteria,46478@72275|Alteromonadaceae 1236|Gammaproteobacteria L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG GO:0003674,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB_bind,DnaG_DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2 k141_13378_1 1499685.CCFJ01000057_gene525 1.68e-33 120.0 2CDF4@1|root,32RXN@2|Bacteria,1VACE@1239|Firmicutes,4HKM4@91061|Bacilli,1ZHZZ@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF1360) yjcA - - - - - - - - - - - DUF1360 k141_13378_2 218284.CCDN010000005_gene3306 6.11e-62 192.0 29X3J@1|root,30ISA@2|Bacteria,1V4YJ@1239|Firmicutes,4HHNC@91061|Bacilli,1ZDHZ@1386|Bacillus 91061|Bacilli S Spore coat protein Z cotY - - ko:K06343 - - - - ko00000 - - - Spore-coat_CotZ k141_7414_1 218284.CCDN010000002_gene2269 2.05e-72 225.0 COG0122@1|root,COG0122@2|Bacteria,1TQAF@1239|Firmicutes,4HBYM@91061|Bacilli,1ZCV5@1386|Bacillus 91061|Bacilli L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase yfjP GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003824,GO:0003905,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008725,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0032131,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0043733,GO:0043916,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.2.2.21 ko:K01247 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - HhH-GPD k141_7414_2 1034347.CAHJ01000047_gene179 2.91e-22 93.2 2DNZX@1|root,32ZZB@2|Bacteria,1VHU6@1239|Firmicutes,4HNSN@91061|Bacilli,1ZIW5@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF4362) - - - - - - - - - - - - DUF3221,DUF4362 k141_22856_1 1279017.AQYJ01000029_gene3371 8.78e-06 48.1 COG2386@1|root,COG2386@2|Bacteria,1NJB0@1224|Proteobacteria,1RRFJ@1236|Gammaproteobacteria,466DX@72275|Alteromonadaceae 1236|Gammaproteobacteria O Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes ccmB GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0031224,GO:0031226,GO:0032991,GO:0042623,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - ko:K02194 ko02010,map02010 M00259 - - ko00000,ko00001,ko00002,ko02000 3.A.1.107 - iECO111_1330.ECO111_2936,iYL1228.KPN_02080 CcmB k141_22856_2 1279017.AQYJ01000029_gene3370 2.2e-96 287.0 COG4133@1|root,COG4133@2|Bacteria,1MZPC@1224|Proteobacteria,1S3R2@1236|Gammaproteobacteria,466VK@72275|Alteromonadaceae 1236|Gammaproteobacteria O once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system ccmA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0009898,GO:0015232,GO:0015886,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019897,GO:0019898,GO:0022857,GO:0031224,GO:0031234,GO:0032991,GO:0042623,GO:0043190,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051181,GO:0051184,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098533,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:1901678,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.41 ko:K02193 ko02010,map02010 M00259 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.107 - iAPECO1_1312.APECO1_4358,iECED1_1282.ECED1_2666,iECS88_1305.ECS88_2348,iECUMN_1333.ECUMN_2536,iLF82_1304.LF82_0273,iNRG857_1313.NRG857_11170,iUMN146_1321.UM146_05800,iUTI89_1310.UTI89_C2479 ABC_tran k141_22856_3 1216007.AOPM01000046_gene2410 7.76e-33 135.0 COG2208@1|root,COG3437@1|root,COG2208@2|Bacteria,COG3437@2|Bacteria,1N4K5@1224|Proteobacteria,1RNYP@1236|Gammaproteobacteria,2PZYV@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria T COG0784 FOG CheY-like receiver - - - ko:K20977 ko02020,ko02025,map02020,map02025 M00820 - - ko00000,ko00001,ko00002,ko02022 - - - HATPase_c_2,Response_reg,SpoIIE k141_25231_1 218284.CCDN010000010_gene4391 5.38e-103 307.0 COG4956@1|root,COG4956@2|Bacteria,1TP0P@1239|Firmicutes,4H9NQ@91061|Bacilli,1ZB5A@1386|Bacillus 91061|Bacilli S COG4956 Integral membrane protein (PIN domain superfamily) yacL GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - - - - - - - - - - TRAM k141_7415_1 218284.CCDN010000001_gene1302 4.53e-112 336.0 COG0477@1|root,COG2814@2|Bacteria,1VSW8@1239|Firmicutes,4HUQC@91061|Bacilli,1ZAS8@1386|Bacillus 91061|Bacilli EGP the major facilitator superfamily mdr GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - - - - - - - - - - MFS_1 k141_19252_2 218284.CCDN010000005_gene3331 2.2e-134 392.0 COG0362@1|root,COG0362@2|Bacteria,1TP4I@1239|Firmicutes,4H9NC@91061|Bacilli,1ZC6M@1386|Bacillus 91061|Bacilli G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH gnd - 1.1.1.343,1.1.1.44 ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 M00004,M00006 R01528,R10221 RC00001,RC00539 ko00000,ko00001,ko00002,ko01000 - - - 6PGD,NAD_binding_2 k141_32263_1 218284.CCDN010000005_gene3229 3.31e-240 699.0 COG1074@1|root,COG1074@2|Bacteria,1TQ35@1239|Firmicutes,4HA64@91061|Bacilli,1ZBG6@1386|Bacillus 91061|Bacilli L ATP-dependent helicase nuclease subunit A addA GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 3.6.4.12 ko:K16898 - - - - ko00000,ko01000,ko03400 - - - PDDEXK_1,UvrD-helicase,UvrD_C k141_22858_1 218284.CCDN010000001_gene807 3.01e-115 340.0 COG2866@1|root,COG2866@2|Bacteria,1TP3K@1239|Firmicutes,4HAHN@91061|Bacilli,1ZD1J@1386|Bacillus 91061|Bacilli E Gamma-D-glutamyl-L-diamino acid endopeptidase yqgT GO:0003674,GO:0003824,GO:0004180,GO:0004181,GO:0005575,GO:0005576,GO:0005615,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0044421,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.19.11 ko:K01308 - - - - ko00000,ko01000,ko01002 - - - LysM,Peptidase_M14 k141_21685_2 566466.NOR53_876 3.26e-36 126.0 COG0718@1|root,COG0718@2|Bacteria,1RGZD@1224|Proteobacteria,1S5WU@1236|Gammaproteobacteria,1J6QE@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection ybaB GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:1901363 - ko:K09747 - - - - ko00000 - - - YbaB_DNA_bd k141_13379_1 1453501.JELR01000002_gene772 2.14e-108 333.0 COG0834@1|root,COG4623@1|root,COG0834@2|Bacteria,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,1RM8W@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella - GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - ko:K18691 - - - - ko00000,ko01000,ko01011 - - - SBP_bac_3,SLT k141_12215_2 218284.CCDN010000001_gene1216 3.71e-110 322.0 COG2057@1|root,COG2057@2|Bacteria,1TNY5@1239|Firmicutes,4HBFR@91061|Bacilli,1ZB4Q@1386|Bacillus 91061|Bacilli I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit atoA - 2.8.3.8,2.8.3.9 ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 - R01179,R01359,R01365,R07832 RC00012,RC00014 ko00000,ko00001,ko01000 - - - CoA_trans k141_15735_1 1294265.JCM21738_1661 2.15e-125 363.0 COG0391@1|root,COG0391@2|Bacteria,1TPNV@1239|Firmicutes,4HA0Z@91061|Bacilli,1ZB2R@1386|Bacillus 91061|Bacilli S Required for morphogenesis under gluconeogenic growth conditions yvcK - - - - - - - - - - - UPF0052 k141_25232_3 411468.CLOSCI_00567 3.55e-59 187.0 2CDFK@1|root,2Z8BH@2|Bacteria,1V43D@1239|Firmicutes,24KG0@186801|Clostridia 186801|Clostridia H DNA N-6-adenine-methyltransferase - - - - - - - - - - - - Dam k141_13380_1 218284.CCDN010000001_gene887 2.73e-61 189.0 29ST9@1|root,30DZ9@2|Bacteria,1UBX8@1239|Firmicutes,4INCZ@91061|Bacilli,1ZNA4@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_19253_1 218284.CCDN010000002_gene2232 1.19e-13 70.1 COG3486@1|root,COG3486@2|Bacteria,1UZAQ@1239|Firmicutes,4HBWJ@91061|Bacilli,1ZB3E@1386|Bacillus 91061|Bacilli Q L-lysine 6-monooxygenase (NADPH-requiring) - - 1.14.13.59 ko:K03897 ko00310,ko01120,map00310,map01120 - R00448 RC00298 ko00000,ko00001,ko01000 - - - K_oxygenase k141_20396_1 501479.ACNW01000095_gene1608 4.3e-104 330.0 COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,2TRQG@28211|Alphaproteobacteria 28211|Alphaproteobacteria D Required for chromosome condensation and partitioning smc - - ko:K03529 - - - - ko00000,ko03036 - - - SMC_N k141_31201_1 1294265.JCM21738_5030 5.84e-73 219.0 29T3A@1|root,30E9U@2|Bacteria,1UCAN@1239|Firmicutes,4INT3@91061|Bacilli,1ZNWZ@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_359_1 218284.CCDN010000001_gene386 5.33e-139 408.0 COG0778@1|root,COG0778@2|Bacteria,1UWU9@1239|Firmicutes,4H9ZQ@91061|Bacilli,1ZDAF@1386|Bacillus 91061|Bacilli C Nitroreductase family - - - - - - - - - - - - Nitroreductase k141_21686_1 1279017.AQYJ01000028_gene2068 4.99e-38 142.0 COG0810@1|root,COG0810@2|Bacteria,1R65W@1224|Proteobacteria,1S133@1236|Gammaproteobacteria,466F5@72275|Alteromonadaceae 1236|Gammaproteobacteria M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - - - - - - - - - - - k141_6325_1 1042377.AFPJ01000021_gene2128 6.01e-45 157.0 COG0122@1|root,COG2169@1|root,COG0122@2|Bacteria,COG2169@2|Bacteria,1QTXM@1224|Proteobacteria,1RNQB@1236|Gammaproteobacteria,464XA@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG2169 Adenosine deaminase ada - 3.2.2.21 ko:K01247,ko:K13529 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03000,ko03400 - - - Ada_Zn_binding,AlkA_N,HTH_18,HhH-GPD k141_6325_2 1453501.JELR01000001_gene2924 7.45e-96 281.0 COG0350@1|root,COG0350@2|Bacteria,1N2YQ@1224|Proteobacteria,1S68H@1236|Gammaproteobacteria,467W5@72275|Alteromonadaceae 1236|Gammaproteobacteria L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated ogt - 2.1.1.63 ko:K00567 - - - - ko00000,ko01000,ko03400 - - - DNA_binding_1,Methyltransf_1N k141_6325_3 1042377.AFPJ01000021_gene2130 2.58e-66 204.0 COG0663@1|root,COG0663@2|Bacteria,1RD76@1224|Proteobacteria,1S3WC@1236|Gammaproteobacteria,466YX@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily yrdA - - - - - - - - - - - Hexapep,Hexapep_2 k141_4983_2 1294265.JCM21738_3237 1.97e-57 178.0 COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,4HKHD@91061|Bacilli,1ZGZ0@1386|Bacillus 91061|Bacilli J Binds together with S18 to 16S ribosomal RNA rpsF GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - ko:K02990 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S6 k141_32264_1 545693.BMQ_1173 6.89e-87 261.0 COG0363@1|root,COG0363@2|Bacteria,1TP10@1239|Firmicutes,4HAG4@91061|Bacilli,1ZD28@1386|Bacillus 91061|Bacilli G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion nagB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 3.5.99.6 ko:K02564 ko00520,ko01100,map00520,map01100 - R00765 RC00163 ko00000,ko00001,ko01000 - - iYO844.BSU35020 Glucosamine_iso k141_12216_1 1246484.D479_04800 4.77e-158 458.0 COG1966@1|root,COG1966@2|Bacteria,1TQN8@1239|Firmicutes,4H9SU@91061|Bacilli,3NE3X@45667|Halobacillus 91061|Bacilli T 5TM C-terminal transporter carbon starvation CstA cstA_1 - - ko:K06200 - - - - ko00000 - - - CstA,CstA_5TM k141_13381_1 218284.CCDN010000001_gene1328 2.83e-222 621.0 COG5002@1|root,COG5002@2|Bacteria,1TPSK@1239|Firmicutes,4HAH5@91061|Bacilli,1ZB8J@1386|Bacillus 91061|Bacilli T Histidine kinase arlS GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 2.7.13.3 ko:K18940 ko02020,map02020 M00716,M00717 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA k141_19272_1 1157490.EL26_12220 4.78e-09 57.8 COG1668@1|root,COG1668@2|Bacteria,1V5UX@1239|Firmicutes,4HJFQ@91061|Bacilli 91061|Bacilli CP ABC-2 family transporter protein - - - - - - - - - - - - ABC2_membrane_2 k141_8599_1 1280001.BAOA01000075_gene3221 4.29e-260 726.0 COG1299@1|root,COG1445@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,1MXFN@1224|Proteobacteria,1RMZC@1236|Gammaproteobacteria,1XSC5@135623|Vibrionales 135623|Vibrionales G COG1445 Phosphotransferase system fructose-specific component IIB fruA - 2.7.1.202 ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1 - - PTS_EIIC,PTS_IIB k141_8599_2 1116375.VEJY3_20166 3.97e-207 576.0 COG1105@1|root,COG1105@2|Bacteria,1MVNW@1224|Proteobacteria,1RP6K@1236|Gammaproteobacteria,1XSVH@135623|Vibrionales 135623|Vibrionales H belongs to the carbohydrate kinase PfkB family fruK - 2.7.1.56 ko:K00882 ko00051,map00051 - R02071 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB k141_8599_3 1116375.VEJY3_20161 2.61e-244 674.0 COG1925@1|root,COG4668@1|root,COG1925@2|Bacteria,COG4668@2|Bacteria,1MVP6@1224|Proteobacteria,1RQP4@1236|Gammaproteobacteria,1XSJ1@135623|Vibrionales 135623|Vibrionales G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain fruB - 2.7.1.202 ko:K02768,ko:K11183 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1 - - PTS-HPr,PTS_EIIA_2 k141_30076_1 675812.VHA_002553 1.32e-201 586.0 COG3250@1|root,COG3250@2|Bacteria,1MVBN@1224|Proteobacteria,1RMER@1236|Gammaproteobacteria,1XUKN@135623|Vibrionales 135623|Vibrionales G COG3250 Beta-galactosidase beta-glucuronidase ebgA - 3.2.1.23 ko:K12111 ko00052,ko00511,ko01100,map00052,map00511,map01100 - R01678,R06114 RC00049 ko00000,ko00001,ko01000 - - - Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N k141_30076_2 754436.JCM19237_2067 1.45e-87 259.0 COG2731@1|root,COG2731@2|Bacteria,1RGW2@1224|Proteobacteria,1S72G@1236|Gammaproteobacteria,1XWXX@135623|Vibrionales 135623|Vibrionales G COG2731 Beta-galactosidase, beta subunit ebgC - - ko:K12112 ko00052,ko00511,ko01100,map00052,map00511,map01100 - R01678 RC00049 ko00000,ko00001 - - - DUF386 k141_5245_1 1116375.VEJY3_17486 9.23e-60 188.0 COG1280@1|root,COG1280@2|Bacteria,1RDPB@1224|Proteobacteria,1S3J3@1236|Gammaproteobacteria,1Y2QB@135623|Vibrionales 135623|Vibrionales E LysE type translocator - - - - - - - - - - - - LysE k141_5245_2 1116375.VEJY3_17481 3.17e-206 572.0 COG0583@1|root,COG0583@2|Bacteria,1N663@1224|Proteobacteria,1S2UC@1236|Gammaproteobacteria,1XSZU@135623|Vibrionales 135623|Vibrionales K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_5245_3 1116375.VEJY3_17476 7.25e-100 290.0 COG1522@1|root,COG1522@2|Bacteria,1N2D6@1224|Proteobacteria,1S8VT@1236|Gammaproteobacteria,1XXCI@135623|Vibrionales 135623|Vibrionales K COG1522 Transcriptional regulators VVA1240 - - - - - - - - - - - AsnC_trans_reg,HTH_24,HTH_AsnC-type k141_5245_4 1116375.VEJY3_17471 9.57e-271 744.0 COG0531@1|root,COG0531@2|Bacteria,1NCSX@1224|Proteobacteria,1RND7@1236|Gammaproteobacteria,1XUR8@135623|Vibrionales 135623|Vibrionales E COG0531 Amino acid transporters - - - ko:K16263 - - - - ko00000,ko02000 2.A.3.13 - - AA_permease_2 k141_5245_5 1116375.VEJY3_17466 3.61e-295 811.0 COG1167@1|root,COG1167@2|Bacteria,1MVGT@1224|Proteobacteria,1RPFK@1236|Gammaproteobacteria,1XTBA@135623|Vibrionales 135623|Vibrionales K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs - - - ko:K00375 - - - - ko00000,ko03000 - - - Aminotran_1_2,GntR k141_5245_6 1116375.VEJY3_17461 1.06e-134 384.0 COG3467@1|root,COG3467@2|Bacteria,1MWQE@1224|Proteobacteria,1S8BX@1236|Gammaproteobacteria,1XUYD@135623|Vibrionales 135623|Vibrionales S Flavin-nucleotide-binding protein - - - ko:K07005 - - - - ko00000 - - - Pyridox_ox_2 k141_5245_7 1116375.VEJY3_17456 1.39e-280 771.0 COG0661@1|root,COG0661@2|Bacteria,1MW1J@1224|Proteobacteria,1RYAY@1236|Gammaproteobacteria,1XTDW@135623|Vibrionales 135623|Vibrionales S unusual protein kinase - - - - - - - - - - - - ABC1 k141_5245_8 223926.28809608 1.98e-284 781.0 COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,1RNE4@1236|Gammaproteobacteria,1XV0R@135623|Vibrionales 135623|Vibrionales P COG2239 Mg Co Ni transporter MgtE (contains CBS domain) mgtE - - ko:K06213 - - - - ko00000,ko02000 1.A.26.1 - - CBS,MgtE,MgtE_N k141_5245_9 1116375.VEJY3_17446 6.85e-109 316.0 COG1418@1|root,COG1418@2|Bacteria,1RB2W@1224|Proteobacteria,1RR38@1236|Gammaproteobacteria,1XX5W@135623|Vibrionales 135623|Vibrionales S HD superfamily hydrolase - - - ko:K06950 - - - - ko00000 - - - HD k141_26827_1 1121920.AUAU01000020_gene2550 2.74e-13 71.6 COG0433@1|root,COG0433@2|Bacteria,3Y69X@57723|Acidobacteria 57723|Acidobacteria S Bacterial protein of unknown function (DUF853) - - - - - - - - - - - - DUF853 k141_610_1 501479.ACNW01000094_gene1484 1.53e-121 350.0 COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,2TUQM@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria kdsB - 2.7.7.38 ko:K00979 ko00540,ko01100,map00540,map01100 M00063 R03351,R11396 RC00152,RC00910 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CTP_transf_3 k141_13678_1 1279017.AQYJ01000028_gene2544 6.29e-289 799.0 COG3288@1|root,COG3288@2|Bacteria,1MVXU@1224|Proteobacteria,1RN23@1236|Gammaproteobacteria,4658N@72275|Alteromonadaceae 1236|Gammaproteobacteria C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane pntA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006740,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008746,GO:0008750,GO:0009117,GO:0009987,GO:0016020,GO:0016021,GO:0016491,GO:0016651,GO:0016652,GO:0019362,GO:0019637,GO:0031224,GO:0031226,GO:0034641,GO:0036094,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0046483,GO:0046496,GO:0046983,GO:0048037,GO:0050661,GO:0050662,GO:0051186,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072524,GO:0097159,GO:1901265,GO:1901360,GO:1901363,GO:1901564 1.6.1.2 ko:K00324 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - iEcE24377_1341.EcE24377A_1810 AlaDh_PNT_C,AlaDh_PNT_N,PNTB_4TM k141_13678_3 930169.B5T_03599 3.79e-186 538.0 COG0793@1|root,COG0793@2|Bacteria,1MUA3@1224|Proteobacteria,1RR5H@1236|Gammaproteobacteria,1XN4Y@135619|Oceanospirillales 135619|Oceanospirillales M Peptidase family S41 - - - - - - - - - - - - Peptidase_S41 k141_8845_1 1116375.VEJY3_16566 1.61e-158 449.0 COG1840@1|root,COG1840@2|Bacteria,1MXZ8@1224|Proteobacteria,1RPPC@1236|Gammaproteobacteria,1XSDQ@135623|Vibrionales 135623|Vibrionales P ABC-type Fe3 transport system, periplasmic component - - - ko:K02012 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - SBP_bac_6 k141_8845_2 1116375.VEJY3_16561 9.82e-259 710.0 COG0075@1|root,COG0075@2|Bacteria,1MWHJ@1224|Proteobacteria,1RNNI@1236|Gammaproteobacteria,1XT31@135623|Vibrionales 135623|Vibrionales E Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily phnW GO:0003674,GO:0003824 2.6.1.37 ko:K03430 ko00440,ko01100,ko01120,map00440,map01100,map01120 - R04152 RC00008,RC00062 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_5 k141_8845_3 223926.28808372 2.64e-68 218.0 COG0160@1|root,COG0160@2|Bacteria,1QTZ3@1224|Proteobacteria,1RXZS@1236|Gammaproteobacteria,1XU9C@135623|Vibrionales 135623|Vibrionales H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - 2.6.1.19 ko:K00823 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 M00027 R00908,R01648 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 k141_11208_1 1279017.AQYJ01000024_gene1095 2.39e-119 352.0 COG1364@1|root,COG1364@2|Bacteria,1MU0T@1224|Proteobacteria,1RNVF@1236|Gammaproteobacteria,464AB@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate argJ - 2.3.1.1,2.3.1.35 ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R00259,R02282 RC00004,RC00064 ko00000,ko00001,ko00002,ko01000 - - - ArgJ k141_11208_3 1279017.AQYJ01000024_gene1096 4.27e-64 198.0 COG0494@1|root,COG0494@2|Bacteria,1RCZM@1224|Proteobacteria,1RS3S@1236|Gammaproteobacteria,467U6@72275|Alteromonadaceae 1236|Gammaproteobacteria L Belongs to the Nudix hydrolase family mutT GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008413,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017110,GO:0030145,GO:0033554,GO:0034641,GO:0035539,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044715,GO:0044716,GO:0046483,GO:0046872,GO:0046914,GO:0047429,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - iE2348C_1286.E2348C_0104,iSDY_1059.SDY_0129 NUDIX,NUDIX_4,TMP-TENI k141_4099_1 1280001.BAOA01000085_gene3614 8.68e-68 206.0 COG1942@1|root,COG1942@2|Bacteria,1N7M2@1224|Proteobacteria,1SCAG@1236|Gammaproteobacteria,1XY1W@135623|Vibrionales 135623|Vibrionales S Domain of unknown function (DUF1904) - - - - - - - - - - - - DUF1904 k141_4099_2 1116375.VEJY3_02575 3.97e-67 203.0 2E8ER@1|root,332T4@2|Bacteria,1ND4F@1224|Proteobacteria,1SERH@1236|Gammaproteobacteria,1XY0T@135623|Vibrionales 135623|Vibrionales - - VP0565 - - - - - - - - - - - - k141_4099_3 223926.28805549 3.1e-58 179.0 COG1145@1|root,COG1145@2|Bacteria,1MZ6H@1224|Proteobacteria,1S8ZV@1236|Gammaproteobacteria,1XYGZ@135623|Vibrionales 135623|Vibrionales C COG1145 Ferredoxin yfhL - - - - - - - - - - - Fer4,Fer4_7 k141_4099_4 223926.28805550 0.0 926.0 COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,1RNPY@1236|Gammaproteobacteria,1XU66@135623|Vibrionales 135623|Vibrionales O COG0826 Collagenase and related proteases - - - ko:K08303 ko05120,map05120 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_U32,Peptidase_U32_C k141_4099_5 1280001.BAOA01000085_gene3610 2e-209 580.0 COG2974@1|root,COG2974@2|Bacteria,1MXPR@1224|Proteobacteria,1RMNN@1236|Gammaproteobacteria,1XT7H@135623|Vibrionales 135623|Vibrionales L May be involved in recombination rdgC - - ko:K03554 - - - - ko00000,ko03400 - - - RdgC k141_4099_6 223926.28805552 1.83e-163 457.0 COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,1RN41@1236|Gammaproteobacteria,1XU4T@135623|Vibrionales 135623|Vibrionales K COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain phoB - - ko:K07657 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C k141_4099_7 1116375.VEJY3_02605 2.93e-174 493.0 COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,1RN0F@1236|Gammaproteobacteria,1XSR8@135623|Vibrionales 135623|Vibrionales T Phosphate regulon sensor protein phoR - 2.7.13.3 ko:K07636 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - DUF3329,HATPase_c,HisKA,PAS k141_12533_1 218284.CCDN010000003_gene2967 4.59e-132 379.0 COG1774@1|root,COG1774@2|Bacteria,1TP1V@1239|Firmicutes,4H9M9@91061|Bacilli,1ZBCK@1386|Bacillus 91061|Bacilli S stage 0 sporulation protein yaaT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - - - - - - - - - - PSP1 k141_5246_1 218284.CCDN010000001_gene1964 1.1e-26 103.0 COG3382@1|root,COG3382@2|Bacteria,1V7YR@1239|Firmicutes,4HGDN@91061|Bacilli,1ZBT2@1386|Bacillus 91061|Bacilli S B3/4 domain yhzB - - - - - - - - - - - B3_4 k141_27660_1 218284.CCDN010000004_gene3062 1.03e-31 115.0 COG1238@1|root,COG1238@2|Bacteria,1V63I@1239|Firmicutes,4HHFZ@91061|Bacilli,1ZG20@1386|Bacillus 91061|Bacilli S SNARE associated Golgi protein - - - - - - - - - - - - SNARE_assoc k141_27660_2 218284.CCDN010000004_gene3063 4.05e-138 399.0 COG1597@1|root,COG1597@2|Bacteria,1TRGQ@1239|Firmicutes,4HDR5@91061|Bacilli,1ZCT6@1386|Bacillus 91061|Bacilli I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase bmrU - - - - - - - - - - - DAGK_cat k141_2803_2 1453501.JELR01000002_gene1256 3.16e-16 73.6 COG3536@1|root,COG3536@2|Bacteria,1MZ5M@1224|Proteobacteria,1S8TB@1236|Gammaproteobacteria,467RD@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF971) - - 5.3.1.16 ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04640 RC00945 ko00000,ko00001,ko00002,ko01000 - - - DUF971 k141_33797_1 1279017.AQYJ01000029_gene3689 7.73e-68 239.0 COG0501@1|root,COG0501@2|Bacteria,1NAW7@1224|Proteobacteria,1SFEN@1236|Gammaproteobacteria,46C96@72275|Alteromonadaceae 1236|Gammaproteobacteria O Belongs to the peptidase M48B family - - - - - - - - - - - - Peptidase_M48 k141_33797_2 1279017.AQYJ01000029_gene3688 4.29e-76 236.0 COG1309@1|root,COG1309@2|Bacteria,1RGJ3@1224|Proteobacteria,1S2ZZ@1236|Gammaproteobacteria,46AWF@72275|Alteromonadaceae 1236|Gammaproteobacteria K Bacterial regulatory proteins, tetR family pfiT - - - - - - - - - - - TetR_C_4,TetR_N k141_33797_3 1279017.AQYJ01000029_gene3687 4.21e-157 447.0 COG1028@1|root,COG1028@2|Bacteria,1PFUB@1224|Proteobacteria,1RS3G@1236|Gammaproteobacteria,466BV@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) atuB - - ko:K13774 ko00281,map00281 - R08087,R08096,R10125,R10126 RC00080,RC00087 ko00000,ko00001 - - - adh_short_C2 k141_33797_4 1279017.AQYJ01000029_gene3686 1.01e-310 855.0 COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,1RNV5@1236|Gammaproteobacteria,46672@72275|Alteromonadaceae 1236|Gammaproteobacteria I Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) atuC - 6.4.1.5 ko:K13778 ko00281,map00281 - R03494 RC00367,RC00942 ko00000,ko00001,ko01000 - - - Carboxyl_trans k141_33797_5 1279017.AQYJ01000029_gene3685 6.61e-222 619.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RW1Q@1236|Gammaproteobacteria,4663X@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1960 Acyl-CoA dehydrogenases atuD - - ko:K11731 ko00281,map00281 - R08089 RC01893 ko00000,ko00001,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_33797_6 1279017.AQYJ01000029_gene3684 2.53e-81 252.0 COG1024@1|root,COG1024@2|Bacteria,1MVEC@1224|Proteobacteria,1RP85@1236|Gammaproteobacteria,4670X@72275|Alteromonadaceae 1236|Gammaproteobacteria I enoyl-CoA hydratase atuE - 4.2.1.57 ko:K13779 ko00281,map00281 - R03493 RC00941 ko00000,ko00001,ko01000 - - - ECH_1 k141_33797_7 1279017.AQYJ01000029_gene3683 4.96e-254 723.0 COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,1RM95@1236|Gammaproteobacteria,465BW@72275|Alteromonadaceae 1236|Gammaproteobacteria I Acetyl propionyl-CoA carboxylase, alpha subunit mccA - 6.4.1.4,6.4.1.5 ko:K01968,ko:K13777 ko00280,ko00281,ko01100,map00280,map00281,map01100 M00036 R03494,R04138 RC00367,RC00942 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2 k141_33797_8 1279017.AQYJ01000029_gene3682 2.96e-199 558.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RQ5M@1236|Gammaproteobacteria,464GY@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1960 Acyl-CoA dehydrogenases - - 1.3.8.7 ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_26830_1 234267.Acid_7009 5.11e-42 158.0 COG1305@1|root,COG3063@1|root,COG3071@1|root,COG1305@2|Bacteria,COG3063@2|Bacteria,COG3071@2|Bacteria,3Y5KB@57723|Acidobacteria 57723|Acidobacteria E Domain of Unknown Function with PDB structure (DUF3857) - - - - - - - - - - - - DUF3857,Transglut_core k141_30078_1 1217715.F994_01150 1.67e-15 74.7 COG0302@1|root,COG0302@2|Bacteria,1MY3N@1224|Proteobacteria,1RMQM@1236|Gammaproteobacteria,3NKQ6@468|Moraxellaceae 1236|Gammaproteobacteria H GTP cyclohydrolase folE GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 ko:K01495 ko00790,ko01100,map00790,map01100 M00126,M00841,M00842,M00843 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 - - - GTP_cyclohydroI k141_30078_2 1453501.JELR01000001_gene1823 1.34e-55 181.0 COG2890@1|root,COG2890@2|Bacteria,1MX8Q@1224|Proteobacteria,1RPHQ@1236|Gammaproteobacteria,464PR@72275|Alteromonadaceae 1236|Gammaproteobacteria J Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue prmB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006304,GO:0006305,GO:0006306,GO:0006464,GO:0006479,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009007,GO:0009008,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0032775,GO:0034641,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044728,GO:0046483,GO:0071704,GO:0090304,GO:0140096,GO:0140097,GO:1901360,GO:1901564 2.1.1.298 ko:K07320 - - R10806 RC00003,RC03279 ko00000,ko01000,ko03009 - - - MTS k141_15886_1 1122621.ATZA01000032_gene3010 3.53e-83 263.0 COG3191@1|root,COG3191@2|Bacteria,4NGDT@976|Bacteroidetes,1IR0G@117747|Sphingobacteriia 976|Bacteroidetes EQ Peptidase family S58 - - 3.4.11.19 ko:K01266 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S58 k141_611_1 1453501.JELR01000005_gene1779 3.84e-82 254.0 COG4966@1|root,COG4966@2|Bacteria,1R5YK@1224|Proteobacteria,1RZIZ@1236|Gammaproteobacteria,467VQ@72275|Alteromonadaceae 1236|Gammaproteobacteria NU Type IV Pilus-assembly protein W pilW - - ko:K02672 - - - - ko00000,ko02035,ko02044 - - - N_methyl,PilW k141_611_2 1042377.AFPJ01000029_gene541 3.27e-51 166.0 COG4967@1|root,COG4967@2|Bacteria,1N6TG@1224|Proteobacteria,1SC9Z@1236|Gammaproteobacteria,46937@72275|Alteromonadaceae 1236|Gammaproteobacteria NU COG4967 Tfp pilus assembly protein PilV pilV - - ko:K02671 - - - - ko00000,ko02035,ko02044 - - - N_methyl k141_31349_2 218284.CCDN010000008_gene4243 4.72e-32 121.0 COG0123@1|root,COG0123@2|Bacteria,1TQF7@1239|Firmicutes,4HBTF@91061|Bacilli,1ZC2K@1386|Bacillus 91061|Bacilli BQ histone deacetylase acuC - - ko:K04768 - - - - ko00000 - - iYO844.BSU29710 Hist_deacetyl k141_25519_1 1116375.VEJY3_10255 0.0 919.0 COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,1RMSE@1236|Gammaproteobacteria,1XSGC@135623|Vibrionales 135623|Vibrionales E COG0147 Anthranilate para-aminobenzoate synthases component I trpE GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.1.3.27 ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Anth_synt_I_N,Chorismate_bind k141_25519_2 1116375.VEJY3_10245 1.83e-199 553.0 COG0613@1|root,COG0613@2|Bacteria,1MWIH@1224|Proteobacteria,1RNCG@1236|Gammaproteobacteria,1XSAZ@135623|Vibrionales 135623|Vibrionales S metal-dependent phosphoesterases (PHP family) trpH - 3.1.3.97 ko:K07053 - - R00188,R11188 RC00078 ko00000,ko01000 - - - PHP k141_25519_3 1280001.BAOA01000128_gene1219 1.36e-132 377.0 COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,1RNU8@1236|Gammaproteobacteria,1XTRN@135623|Vibrionales 135623|Vibrionales J Belongs to the SUA5 family yciO - - - - - - - - - - - Sua5_yciO_yrdC k141_636_1 218284.CCDN010000004_gene3024 5.85e-102 315.0 COG2183@1|root,COG2183@2|Bacteria,1TPFE@1239|Firmicutes,4HAGY@91061|Bacilli,1ZC3T@1386|Bacillus 91061|Bacilli K COG2183 Transcriptional accessory protein tex - - ko:K06959 - - - - ko00000 - - - HHH_3,S1,Tex_N,Tex_YqgF k141_4113_1 1294265.JCM21738_2676 3.01e-74 224.0 2EEB8@1|root,3385J@2|Bacteria,1VM15@1239|Firmicutes,4HPJI@91061|Bacilli,1ZJ91@1386|Bacillus 91061|Bacilli S Spore germination protein GerPE gerPE - - ko:K06303 - - - - ko00000 - - - GerPE k141_11250_1 218284.CCDN010000001_gene1893 2.94e-222 653.0 COG2176@1|root,COG2176@2|Bacteria,1TPAG@1239|Firmicutes,4H9RF@91061|Bacilli,1ZCIB@1386|Bacillus 91061|Bacilli L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity polC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.7.7 ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_a_NI,DNA_pol3_a_NII,DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon k141_34969_1 1123226.KB899285_gene3923 6.29e-12 65.1 COG1215@1|root,COG1215@2|Bacteria,1TRAD@1239|Firmicutes,4HAR8@91061|Bacilli,26S7X@186822|Paenibacillaceae 91061|Bacilli M glycosyl transferase family 2 crtQ - - ko:K10211 ko00906,map00906 - R07655 RC00523 ko00000,ko00001,ko01000 - - - Glycos_transf_2 k141_34969_2 218284.CCDN010000002_gene2510 5.1e-98 299.0 COG1233@1|root,COG1233@2|Bacteria,1TS4A@1239|Firmicutes,4HB9J@91061|Bacilli,1ZCTK@1386|Bacillus 91061|Bacilli Q COG1233 Phytoene dehydrogenase and related proteins crtN - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 ko:K10027 ko00906,ko01100,ko01110,map00906,map01100,map01110 - R04787,R04798,R04800,R09691,R09692 RC01214,RC02088,RC02605 ko00000,ko00001,ko01000 - - - Amino_oxidase,NAD_binding_8 k141_24195_1 406124.ACPC01000009_gene1590 3.4e-44 152.0 COG2070@1|root,COG2070@2|Bacteria,1TPC3@1239|Firmicutes,4H9T0@91061|Bacilli,1ZBRG@1386|Bacillus 91061|Bacilli S COG2070 Dioxygenases related to 2-nitropropane dioxygenase - - 1.3.1.9 ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00083 R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765 RC00052,RC00076 ko00000,ko00001,ko00002,ko01000,ko01004 - - - NMO k141_5297_1 1123236.KB899377_gene175 1.59e-53 184.0 COG2943@1|root,COG2943@2|Bacteria,1MVXZ@1224|Proteobacteria,1RMGX@1236|Gammaproteobacteria,465E9@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG2943 Membrane glycosyltransferase mdoH GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0005975,GO:0005976,GO:0006073,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009311,GO:0009312,GO:0009628,GO:0009987,GO:0016020,GO:0016021,GO:0016051,GO:0016740,GO:0016757,GO:0031224,GO:0031226,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051273,GO:0051274,GO:0071704,GO:0071944,GO:1901576 - ko:K03669 - - - - ko00000,ko01000,ko01003,ko02000 4.D.3.1.1 GT2 - Glyco_trans_2_3,Glycos_transf_2 k141_5297_2 1123236.KB899377_gene174 1.32e-35 132.0 COG3131@1|root,COG3131@2|Bacteria,1MUNX@1224|Proteobacteria,1RMEB@1236|Gammaproteobacteria,4654Q@72275|Alteromonadaceae 1236|Gammaproteobacteria P Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) mdoG - - ko:K03670 - - - - ko00000 - - - MdoG k141_33823_1 218284.CCDN010000001_gene1753 1.18e-159 455.0 COG0180@1|root,COG0180@2|Bacteria,1TPY7@1239|Firmicutes,4HE96@91061|Bacilli,1ZE1U@1386|Bacillus 91061|Bacilli J Catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA - - 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1b k141_5298_1 525904.Tter_1099 5.72e-21 96.7 COG2856@1|root,COG2856@2|Bacteria,2NQY0@2323|unclassified Bacteria 2|Bacteria E Zn peptidase - - - - - - - - - - - - - k141_20652_2 1042377.AFPJ01000032_gene2741 1.64e-177 497.0 COG0685@1|root,COG0685@2|Bacteria,1MUC9@1224|Proteobacteria,1RMXS@1236|Gammaproteobacteria,465ZB@72275|Alteromonadaceae 1236|Gammaproteobacteria E reductase metF GO:0000166,GO:0003674,GO:0003824,GO:0004489,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0022607,GO:0034641,GO:0036094,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.5.1.20 ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 M00377 R01224,R07168 RC00081 ko00000,ko00001,ko00002,ko01000 - - iPC815.YPO0117,iSBO_1134.SBO_3961 MTHFR k141_25520_2 1116375.VEJY3_08870 8.14e-69 210.0 COG3631@1|root,COG3631@2|Bacteria,1N05P@1224|Proteobacteria,1SBGY@1236|Gammaproteobacteria,1XX56@135623|Vibrionales 135623|Vibrionales S SnoaL-like domain - - - - - - - - - - - - SnoaL_2 k141_15906_1 218284.CCDN010000002_gene2281 4.18e-74 229.0 COG2186@1|root,COG2186@2|Bacteria,1V5E3@1239|Firmicutes,4HI4R@91061|Bacilli,1ZGPE@1386|Bacillus 91061|Bacilli K FadR C-terminal domain - - - ko:K03603 - - - - ko00000,ko03000 - - - FadR_C,GntR k141_34971_2 1461580.CCAS010000008_gene1188 5.2e-109 318.0 COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,4HA59@91061|Bacilli,1ZAYV@1386|Bacillus 91061|Bacilli I Dehydrogenase mmgB - 1.1.1.157 ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 - R01976,R05576,R06941 RC00029,RC00117 ko00000,ko00001,ko01000 - - - 3HCDH,3HCDH_N k141_36049_1 1294265.JCM21738_1786 9.34e-134 379.0 COG0243@1|root,COG0243@2|Bacteria,1V2XY@1239|Firmicutes,4HWR9@91061|Bacilli,1ZB6J@1386|Bacillus 91061|Bacilli C COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing - - 1.17.1.9 ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001,ko01000 - - - Molybdop_Fe4S4,Molybdopterin,TAT_signal k141_36049_2 1499680.CCFE01000013_gene939 7.22e-120 365.0 COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,1TQIX@1239|Firmicutes,4HUSZ@91061|Bacilli,1ZCA1@1386|Bacillus 91061|Bacilli C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - 1.17.1.9 ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001,ko01000 - - - Molybdopterin,Molydop_binding k141_23182_1 1280001.BAOA01000217_gene257 2.03e-91 273.0 COG0447@1|root,COG0447@2|Bacteria,1QTZ2@1224|Proteobacteria,1T1TZ@1236|Gammaproteobacteria,1XVFY@135623|Vibrionales 135623|Vibrionales H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) menB - 4.1.3.36 ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R07263 RC01923 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 k141_23182_2 223926.28805917 6.25e-147 418.0 COG2267@1|root,COG2267@2|Bacteria,1QUFU@1224|Proteobacteria,1T1XG@1236|Gammaproteobacteria,1XSP9@135623|Vibrionales 135623|Vibrionales H Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) menH - 4.2.99.20 ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R08166 RC02148,RC02475 ko00000,ko00001,ko00002,ko01000 - - - Abhydrolase_1,Abhydrolase_6 k141_23182_3 1116375.VEJY3_04265 0.0 965.0 COG1165@1|root,COG1165@2|Bacteria,1MVMZ@1224|Proteobacteria,1RNRS@1236|Gammaproteobacteria,1XSZF@135623|Vibrionales 135623|Vibrionales H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) menD GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0008683,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0016833,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.2.1.9 ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R08165 RC02186 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M_2,TPP_enzyme_N k141_23182_4 1116375.VEJY3_04260 3.93e-289 792.0 COG1169@1|root,COG1169@2|Bacteria,1MVB7@1224|Proteobacteria,1RNSR@1236|Gammaproteobacteria,1XTAT@135623|Vibrionales 135623|Vibrionales H Catalyzes the conversion of chorismate to isochorismate menF - 5.4.4.2 ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 M00116 R01717 RC00588 ko00000,ko00001,ko00002,ko01000 - - - Chorismate_bind k141_23182_5 945550.VISI1226_21524 6.22e-92 278.0 COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RN5B@1236|Gammaproteobacteria,1XSWC@135623|Vibrionales 135623|Vibrionales E COG0436 Aspartate tyrosine aromatic aminotransferase alaA - 2.6.1.2,2.6.1.66 ko:K14260 ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230 - R00258,R01215 RC00006,RC00008,RC00036 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 k141_25521_1 997296.PB1_14649 4.41e-59 196.0 COG0750@1|root,COG0750@2|Bacteria,1TPIR@1239|Firmicutes,4H9TW@91061|Bacilli,1ZB04@1386|Bacillus 91061|Bacilli M Stage IV sporulation protein B spoIVB - 3.4.21.116 ko:K06399 - - - - ko00000,ko01000,ko01002 - - - PDZ,PDZ_2,Peptidase_S55 k141_19521_1 218284.CCDN010000001_gene1582 5.62e-64 198.0 COG1476@1|root,COG1476@2|Bacteria,1V7SJ@1239|Firmicutes,4HWTC@91061|Bacilli 91061|Bacilli K Helix-turn-helix - - - - - - - - - - - - HTH_3,PAS_4 k141_19521_2 315730.BcerKBAB4_2554 5.05e-18 77.8 COG0823@1|root,COG0823@2|Bacteria,1VFY2@1239|Firmicutes,4HP5R@91061|Bacilli,1ZIV5@1386|Bacillus 91061|Bacilli U Protein of unknown function (DUF3889) - - - - - - - - - - - - DUF3889 k141_1609_1 1116375.VEJY3_15155 8.1e-182 509.0 COG2962@1|root,COG2962@2|Bacteria,1MX5G@1224|Proteobacteria,1RMAC@1236|Gammaproteobacteria,1XSTP@135623|Vibrionales 135623|Vibrionales S EamA-like transporter family rarD - - ko:K05786 - - - - ko00000,ko02000 2.A.7.7 - - EamA k141_1609_2 223926.28808033 1.48e-172 496.0 COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,1RMPG@1236|Gammaproteobacteria,1XU5H@135623|Vibrionales 135623|Vibrionales L DNA helicase recQ - 3.6.4.12 ko:K03654 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind k141_20653_1 218284.CCDN010000001_gene1262 8.37e-156 441.0 COG4667@1|root,COG4667@2|Bacteria,1TQ9W@1239|Firmicutes,4HCHJ@91061|Bacilli,1ZD2S@1386|Bacillus 91061|Bacilli S Patatin-like phospholipase - - - - - - - - - - - - Patatin k141_5300_2 28229.ND2E_3900 3.03e-15 76.6 COG0760@1|root,COG0760@2|Bacteria,1R4ZR@1224|Proteobacteria,1SEDW@1236|Gammaproteobacteria,2Q71A@267889|Colwelliaceae 1236|Gammaproteobacteria O PPIC-type PPIASE domain - - - - - - - - - - - - Rotamase_2 k141_24198_2 443143.GM18_2811 3.64e-42 142.0 COG0537@1|root,COG0537@2|Bacteria,1N3EA@1224|Proteobacteria,42WAX@68525|delta/epsilon subdivisions,2WRAN@28221|Deltaproteobacteria,43VHK@69541|Desulfuromonadales 28221|Deltaproteobacteria FG Scavenger mRNA decapping enzyme C-term binding - - - - - - - - - - - - HIT k141_27678_1 1116375.VEJY3_17496 0.0 905.0 COG0057@1|root,COG0057@2|Bacteria,1MZE4@1224|Proteobacteria,1RMSI@1236|Gammaproteobacteria,1XTW0@135623|Vibrionales 135623|Vibrionales C Belongs to the glyceraldehyde-3-phosphate dehydrogenase family gapA-2 - 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N k141_27678_2 345073.VC395_A0869 4.23e-13 65.9 2B697@1|root,31Z6K@2|Bacteria,1QKFI@1224|Proteobacteria,1TIJG@1236|Gammaproteobacteria,1XZ8I@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_27678_3 1219076.N646_3882 1.3e-72 222.0 COG1280@1|root,COG1280@2|Bacteria,1RDPB@1224|Proteobacteria,1S3J3@1236|Gammaproteobacteria,1Y2QB@135623|Vibrionales 135623|Vibrionales E LysE type translocator - - - - - - - - - - - - LysE k141_637_1 1089553.Tph_c18470 1.52e-13 77.8 COG1388@1|root,COG3773@1|root,COG1388@2|Bacteria,COG3773@2|Bacteria,1TRFW@1239|Firmicutes,25B9P@186801|Clostridia,42JDZ@68295|Thermoanaerobacterales 186801|Clostridia M Cell Wall Hydrolase - - 3.5.1.28 ko:K01449 - - R04112 RC00064,RC00141 ko00000,ko01000 - - - Hydrolase_2,LysM k141_5519_1 1042377.AFPJ01000007_gene1926 1.8e-70 231.0 COG0116@1|root,COG1092@1|root,COG0116@2|Bacteria,COG1092@2|Bacteria,1MUQM@1224|Proteobacteria,1RNMH@1236|Gammaproteobacteria,4657X@72275|Alteromonadaceae 1236|Gammaproteobacteria J Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA rlmL GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.173,2.1.1.264 ko:K12297 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - Methyltrans_SAM,THUMP,UPF0020 k141_2940_1 1042377.AFPJ01000043_gene939 3.17e-60 197.0 COG0642@1|root,COG0642@2|Bacteria,1R54G@1224|Proteobacteria,1RWXF@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Histidine kinase colS - - - - - - - - - - - HATPase_c,HisKA k141_27823_1 218284.CCDN010000001_gene550 1.18e-112 331.0 COG0016@1|root,COG0016@2|Bacteria,1TPFW@1239|Firmicutes,4HAVN@91061|Bacilli,1ZANR@1386|Bacillus 91061|Bacilli J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily pheS GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 ko:K01889 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Phe_tRNA-synt_N,tRNA-synt_2d k141_24430_1 1178540.BA70_06415 3.93e-66 209.0 COG0500@1|root,COG2226@2|Bacteria,1TSAZ@1239|Firmicutes,4HFFF@91061|Bacilli,1ZCGP@1386|Bacillus 91061|Bacilli Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_11 k141_27050_1 935837.JAEK01000067_gene3080 3.94e-112 328.0 COG0395@1|root,COG0395@2|Bacteria,1TSD0@1239|Firmicutes,4HC8G@91061|Bacilli,1ZRMG@1386|Bacillus 91061|Bacilli G Binding-protein-dependent transport system inner membrane component yurM - - ko:K10119 ko02010,map02010 M00196 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.28 - - BPD_transp_1 k141_784_1 218284.CCDN010000001_gene39 2.65e-93 275.0 COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,4H9RW@91061|Bacilli,1ZCUF@1386|Bacillus 91061|Bacilli G Belongs to the ribulose-phosphate 3-epimerase family rpe GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 - - - Ribul_P_3_epim k141_29125_1 218284.CCDN010000001_gene1960 4.42e-90 270.0 COG0778@1|root,COG0778@2|Bacteria,1UB8S@1239|Firmicutes,4HEGP@91061|Bacilli,1ZBQ3@1386|Bacillus 91061|Bacilli C Oxidoreductase nfrA1 - 1.5.1.38 ko:K19285 ko00740,ko01100,map00740,map01100 - R05706 RC00126 ko00000,ko00001,ko01000 - - - Nitroreductase k141_24431_1 1279017.AQYJ01000027_gene1961 9.37e-61 192.0 COG2885@1|root,COG2885@2|Bacteria,1REH1@1224|Proteobacteria,1S4WV@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Belongs to the ompA family - - - - - - - - - - - - DUF4398,OmpA k141_9042_1 1279017.AQYJ01000027_gene1711 1.41e-233 654.0 COG1488@1|root,COG1488@2|Bacteria,1MWA2@1224|Proteobacteria,1RPPA@1236|Gammaproteobacteria 1236|Gammaproteobacteria H Nicotinate phosphoribosyltransferase nadV - 2.4.2.12 ko:K03462 ko00760,ko01100,ko04621,map00760,map01100,map04621 - R01271 RC00033 ko00000,ko00001,ko01000 - - - NAPRTase k141_32618_1 218284.CCDN010000006_gene3753 1.47e-35 121.0 2DR42@1|root,33A2M@2|Bacteria,1VKCM@1239|Firmicutes,4HRAS@91061|Bacilli,1ZIVB@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2922) - - - - - - - - - - - - DUF2922 k141_32618_2 665952.HMPREF1015_02007 1.41e-10 58.2 2DR75@1|root,33AHG@2|Bacteria,1VKH9@1239|Firmicutes,4HR4K@91061|Bacilli,1ZJ6X@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF1659) - - - - - - - - - - - - DUF1659 k141_7701_2 1453501.JELR01000001_gene2109 1.36e-63 203.0 COG3803@1|root,COG3803@2|Bacteria,1RHYI@1224|Proteobacteria,1S40A@1236|Gammaproteobacteria,466ZT@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - DUF924 k141_25753_1 935836.JAEL01000007_gene2886 2.72e-110 321.0 COG1183@1|root,COG1183@2|Bacteria,1TR44@1239|Firmicutes,4HF0K@91061|Bacilli,1ZDC6@1386|Bacillus 91061|Bacilli I Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - 2.7.8.8 ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 M00093 R01800 RC00002,RC00017,RC02795 ko00000,ko00001,ko00002,ko01000 - - - CDP-OH_P_transf k141_6644_1 1294265.JCM21738_960 3.55e-38 130.0 COG0596@1|root,COG0596@2|Bacteria,1V619@1239|Firmicutes,4HCRW@91061|Bacilli,1ZDX1@1386|Bacillus 91061|Bacilli S Serine aminopeptidase, S33 yvaM - 1.11.1.10 ko:K00433 - - - - ko00000,ko01000 - - - Abhydrolase_1,Hydrolase_4 k141_2952_1 468059.AUHA01000002_gene585 2.75e-16 81.6 COG2304@1|root,COG2304@2|Bacteria,4NFX3@976|Bacteroidetes,1IP2T@117747|Sphingobacteriia 976|Bacteroidetes P von Willebrand factor, type A - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - CarbopepD_reg_2,DUF3520,VWA,vWF_A k141_2952_2 1453501.JELR01000002_gene1012 3.09e-101 303.0 COG0604@1|root,COG0604@2|Bacteria,1QY04@1224|Proteobacteria,1RSP0@1236|Gammaproteobacteria,46BBM@72275|Alteromonadaceae 1236|Gammaproteobacteria C Zinc-binding dehydrogenase - - 1.1.1.1 ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N,ADH_zinc_N_2,KR,PP-binding,PS-DH k141_37412_1 42565.FP66_15025 7.86e-104 324.0 COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,1RMA7@1236|Gammaproteobacteria,1XHS6@135619|Oceanospirillales 135619|Oceanospirillales E aminopeptidase N pepN - 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - DUF3458,DUF3458_C,Peptidase_M1 k141_23362_1 218284.CCDN010000001_gene1013 1.63e-40 142.0 COG0345@1|root,COG0345@2|Bacteria,1TP1E@1239|Firmicutes,4H9RV@91061|Bacilli,1ZCWZ@1386|Bacillus 91061|Bacilli E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline proC - 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 - - - F420_oxidored,P5CR_dimer k141_32631_1 1122194.AUHU01000008_gene3418 1.01e-30 115.0 COG2186@1|root,COG2186@2|Bacteria,1MV83@1224|Proteobacteria,1RR9F@1236|Gammaproteobacteria,4673U@72275|Alteromonadaceae 1236|Gammaproteobacteria K FCD yieP GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - - - - - - - - - - FCD,GntR k141_7702_1 338966.Ppro_1753 2.69e-101 311.0 COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,42ME5@68525|delta/epsilon subdivisions,2WKA2@28221|Deltaproteobacteria,43TSA@69541|Desulfuromonadales 28221|Deltaproteobacteria J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS proS - 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_2b,tRNA_edit k141_36205_1 218284.CCDN010000001_gene1971 3.77e-266 743.0 COG2972@1|root,COG2972@2|Bacteria,1UU89@1239|Firmicutes,4HECK@91061|Bacilli,1ZAUI@1386|Bacillus 91061|Bacilli T Histidine kinase - - 2.7.13.3 ko:K07718 ko02020,map02020 M00519 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,His_kinase,dCache_1 k141_36205_2 218284.CCDN010000001_gene1970 2.52e-274 762.0 COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TYUA@1239|Firmicutes,4HDKK@91061|Bacilli,1ZPXC@1386|Bacillus 91061|Bacilli T helix_turn_helix, arabinose operon control protein ntrC - - ko:K07720 ko02020,map02020 M00519 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_18,Response_reg k141_6645_1 106582.XP_004560080.1 1.8e-19 82.8 COG0251@1|root,KOG2317@2759|Eukaryota,3A5RT@33154|Opisthokonta,3BQRB@33208|Metazoa,3D86F@33213|Bilateria,48E1Q@7711|Chordata,49AXP@7742|Vertebrata,4A391@7898|Actinopterygii 33208|Metazoa J Heat-responsive protein 12 HRSP12 GO:0001505,GO:0001655,GO:0001822,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0005504,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005759,GO:0005777,GO:0005829,GO:0006082,GO:0006139,GO:0006417,GO:0006457,GO:0006520,GO:0006544,GO:0006566,GO:0006567,GO:0006725,GO:0006807,GO:0007049,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0008150,GO:0008152,GO:0008285,GO:0008289,GO:0009056,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016054,GO:0016070,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0017144,GO:0017148,GO:0019222,GO:0019239,GO:0019518,GO:0019752,GO:0022402,GO:0030323,GO:0030324,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0031974,GO:0032268,GO:0032269,GO:0032501,GO:0032502,GO:0033293,GO:0033993,GO:0034248,GO:0034249,GO:0034641,GO:0035295,GO:0036041,GO:0036094,GO:0042127,GO:0042133,GO:0042221,GO:0042579,GO:0042737,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0046483,GO:0046872,GO:0046914,GO:0046983,GO:0048513,GO:0048519,GO:0048523,GO:0048731,GO:0048856,GO:0050678,GO:0050680,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0060322,GO:0060541,GO:0065007,GO:0065008,GO:0070013,GO:0070314,GO:0071704,GO:0072001,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902074,GO:1904012,GO:1904013,GO:2000112,GO:2000113 3.5.99.10 ko:K09022 - - R11098,R11099 RC03275,RC03354 ko00000,ko01000 - - - Ribonuc_L-PSP k141_6645_2 1449126.JQKL01000025_gene2385 7.03e-54 179.0 COG0709@1|root,COG0709@2|Bacteria,1TQCJ@1239|Firmicutes,247NS@186801|Clostridia,267JH@186813|unclassified Clostridiales 186801|Clostridia E Synthesizes selenophosphate from selenide and ATP selD - 2.7.9.3 ko:K01008 ko00450,ko01100,map00450,map01100 - R03595 RC00002,RC02878 ko00000,ko00001,ko01000,ko03016 - - - AIRS,AIRS_C k141_25754_2 1385513.N780_04150 6.4e-20 90.5 COG0662@1|root,COG0662@2|Bacteria,1V3H4@1239|Firmicutes,4HH1K@91061|Bacilli,2Y9SE@289201|Pontibacillus 91061|Bacilli G Cupin domain - - - - - - - - - - - - Cupin_2 k141_29132_1 218284.CCDN010000001_gene62 6.06e-60 196.0 COG2233@1|root,COG2233@2|Bacteria,1TQKX@1239|Firmicutes,4HAEU@91061|Bacilli,1ZBWN@1386|Bacillus 91061|Bacilli F Xanthine uracil pyrP - - ko:K02824 - - - - ko00000,ko02000 2.A.40.1.1,2.A.40.1.2 - - Xan_ur_permease k141_5543_1 1196028.ALEF01000060_gene1203 4.64e-160 461.0 COG0591@1|root,COG0591@2|Bacteria,1TRK6@1239|Firmicutes,4HEE9@91061|Bacilli,4C4V4@84406|Virgibacillus 91061|Bacilli E Sodium:solute symporter family - - - ko:K11928,ko:K14392 - - - - ko00000,ko02000 2.A.21.1,2.A.21.2 - - SSF k141_5543_2 1196028.ALEF01000060_gene1202 2.04e-169 483.0 COG2141@1|root,COG2141@2|Bacteria,1TQZ0@1239|Firmicutes,4HAF9@91061|Bacilli,4C55W@84406|Virgibacillus 91061|Bacilli C Luciferase-like monooxygenase - - 1.14.14.28 ko:K20938 - - - - ko00000,ko01000 - - - Bac_luciferase k141_33980_1 326297.Sama_1194 1.64e-36 134.0 COG0673@1|root,COG0673@2|Bacteria,1PE56@1224|Proteobacteria,1RWPI@1236|Gammaproteobacteria,2QBFA@267890|Shewanellaceae 1236|Gammaproteobacteria S Glycosyl hydrolase family 109 protein - - - - - - - - - - - - GFO_IDH_MocA,TAT_signal k141_33980_2 94122.Shewana3_2703 6.24e-18 85.1 COG1629@1|root,COG1629@2|Bacteria,1MV8W@1224|Proteobacteria,1RMQA@1236|Gammaproteobacteria,2QA6Z@267890|Shewanellaceae 1236|Gammaproteobacteria M TonB-dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec k141_37413_1 218284.CCDN010000006_gene3526 1.11e-71 225.0 COG0609@1|root,COG0609@2|Bacteria,1TP13@1239|Firmicutes,4HAW8@91061|Bacilli,1ZQ8X@1386|Bacillus 91061|Bacilli P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily yfiZ - - ko:K02015 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - iYO844.BSU08450 FecCD k141_27833_1 573413.Spirs_4247 1.57e-22 96.3 COG1216@1|root,COG1216@2|Bacteria,2J8N9@203691|Spirochaetes 203691|Spirochaetes S Protein of unknown function (DUF616) - - - - - - - - - - - - DUF616 k141_27833_2 380749.HY04AAS1_1577 2.97e-52 181.0 COG0463@1|root,COG0463@2|Bacteria 2|Bacteria M Glycosyl transferase, family 2 - - - ko:K12997 - - - - ko00000,ko01000,ko01003,ko01005 - GT2 - Glycos_transf_2 k141_27833_3 1227500.C494_20173 5.93e-55 187.0 COG0438@1|root,arCOG01409@2157|Archaea 2157|Archaea M PFAM Glycosyl transferase, group 1 - - - - - - - - - - - - Glycos_transf_1 k141_30224_1 218284.CCDN010000003_gene3011 1.76e-139 399.0 COG0115@1|root,COG0115@2|Bacteria,1TSIP@1239|Firmicutes,4HC7K@91061|Bacilli,1ZCRC@1386|Bacillus 91061|Bacilli EH 4-amino-4-deoxychorismate lyase pabC - 4.1.3.38 ko:K02619 ko00790,map00790 - R05553 RC01843,RC02148 ko00000,ko00001,ko01000 - - - Aminotran_4 k141_7704_1 1201292.DR75_353 2.36e-39 146.0 COG4926@1|root,COG4926@2|Bacteria,1TQHW@1239|Firmicutes,4HFA8@91061|Bacilli,4B25H@81852|Enterococcaceae 91061|Bacilli S Prophage endopeptidase tail - - - - - - - - - - - - Prophage_tail k141_23364_1 1273538.G159_05935 9.46e-60 194.0 COG0500@1|root,COG2226@2|Bacteria,1VIXJ@1239|Firmicutes,4HGT9@91061|Bacilli 91061|Bacilli Q ubiE/COQ5 methyltransferase family - - - - - - - - - - - - Methyltransf_11,Methyltransf_25 k141_22035_1 1279017.AQYJ01000026_gene58 4.05e-237 739.0 COG1361@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4932@2|Bacteria,1R5G4@1224|Proteobacteria,1SEWA@1236|Gammaproteobacteria,469S7@72275|Alteromonadaceae 1236|Gammaproteobacteria M Domain of unknown function DUF11 - - - - - - - - - - - - DUF11,SdrD_B k141_37414_1 218284.CCDN010000001_gene1290 6.24e-94 289.0 COG0143@1|root,COG0143@2|Bacteria,1U7TS@1239|Firmicutes,4HDMP@91061|Bacilli,1ZBPT@1386|Bacillus 91061|Bacilli J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation - - 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1g k141_5544_1 42565.FP66_02790 1.15e-154 446.0 COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,1RMY6@1236|Gammaproteobacteria,1XHMS@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA ilvA - 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - - PALP,Thr_dehydrat_C k141_12746_1 1294265.JCM21738_2016 6.11e-108 314.0 COG2252@1|root,COG2252@2|Bacteria,1TQC6@1239|Firmicutes,4HANG@91061|Bacilli,1ZARH@1386|Bacillus 91061|Bacilli S permease pbuG - - ko:K06901 - - - - ko00000,ko02000 2.A.1.40 - - Xan_ur_permease k141_33981_1 997296.PB1_05542 2.01e-92 285.0 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4HBS1@91061|Bacilli,1ZCI4@1386|Bacillus 91061|Bacilli C Belongs to the aldehyde dehydrogenase family. RocA subfamily rocA - 1.2.1.88 ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 - R00245,R00707,R00708,R04444,R04445,R05051 RC00080,RC00216,RC00242,RC00255 ko00000,ko00001,ko01000 - - - Aldedh k141_31407_1 886293.Sinac_0214 6.1e-36 138.0 COG3119@1|root,COG3119@2|Bacteria,2J3IX@203682|Planctomycetes 203682|Planctomycetes P arylsulfatase A - - - - - - - - - - - - Sulfatase,TPR_16,TPR_19,TPR_2 k141_11484_1 1280001.BAOA01000007_gene3982 0.0 1185.0 COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria,1MVCT@1224|Proteobacteria,1RNP1@1236|Gammaproteobacteria,1XT2U@135623|Vibrionales 135623|Vibrionales MV ABC-type antimicrobial peptide transport system, permease component - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD k141_11484_2 1136163.M565_ctg5P1128 1.55e-130 376.0 COG1136@1|root,COG1136@2|Bacteria,1NCFC@1224|Proteobacteria,1SKIN@1236|Gammaproteobacteria,1XUH9@135623|Vibrionales 135623|Vibrionales V ABC-type antimicrobial peptide transport system, ATPase component - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_11484_3 1219065.VPR01S_05_02760 2.98e-102 296.0 COG2329@1|root,COG2329@2|Bacteria,1RAC6@1224|Proteobacteria,1S480@1236|Gammaproteobacteria,1XX6A@135623|Vibrionales 135623|Vibrionales S Domain of unknown function (DUF3291) - - - - - - - - - - - - DUF3291 k141_11484_4 1191299.AJYX01000007_gene2901 6.91e-95 276.0 COG0454@1|root,COG0456@2|Bacteria,1N98J@1224|Proteobacteria,1S9E3@1236|Gammaproteobacteria,1Y2X1@135623|Vibrionales 135623|Vibrionales K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1 k141_11484_5 1001585.MDS_3356 1.61e-51 171.0 2DMZY@1|root,32UNM@2|Bacteria,1NNMB@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_11484_6 1219076.N646_0810 2.58e-106 308.0 COG3153@1|root,COG3153@2|Bacteria,1N4R3@1224|Proteobacteria,1S9FB@1236|Gammaproteobacteria,1XX0Y@135623|Vibrionales 135623|Vibrionales S Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_9 k141_11484_7 1219076.N646_0931 2.04e-88 260.0 COG1670@1|root,COG1670@2|Bacteria,1RJW7@1224|Proteobacteria,1S7A3@1236|Gammaproteobacteria,1XY3U@135623|Vibrionales 135623|Vibrionales J Acetyltransferase (GNAT) domain - - 2.3.1.128 ko:K03790 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 k141_6648_1 1453501.JELR01000002_gene890 1.97e-46 171.0 COG1652@1|root,COG3210@1|root,COG1652@2|Bacteria,COG3210@2|Bacteria,1MXIP@1224|Proteobacteria,1RSAX@1236|Gammaproteobacteria,468YR@72275|Alteromonadaceae 1236|Gammaproteobacteria U haemagglutination activity domain Z012_01725 GO:0005575,GO:0005576 - - - - - - - - - - ESPR,Glug,Haemagg_act k141_29133_2 1236973.JCM9157_4490 1.03e-35 124.0 COG1917@1|root,COG1917@2|Bacteria,1V8DR@1239|Firmicutes,4HJ1Z@91061|Bacilli,1ZHNE@1386|Bacillus 91061|Bacilli S Cupin 2, conserved barrel domain protein - - - - - - - - - - - - Cupin_2 k141_9052_1 935863.AWZR01000002_gene1031 3.24e-97 295.0 COG4973@1|root,COG4973@2|Bacteria,1MUJJ@1224|Proteobacteria,1RMJG@1236|Gammaproteobacteria,1X31C@135614|Xanthomonadales 135614|Xanthomonadales L Belongs to the 'phage' integrase family. XerC subfamily xerC - - ko:K03733 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase k141_9052_3 1279017.AQYJ01000027_gene1632 1.7e-33 116.0 2EQ2V@1|root,33HP8@2|Bacteria,1NI2K@1224|Proteobacteria,1SHMN@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_2954_1 745411.B3C1_08281 5.19e-48 153.0 COG3210@1|root,COG3210@2|Bacteria 2|Bacteria U domain, Protein - - - - - - - - - - - - Big_2,Cytotoxic,Flg_new,Haemagg_act,LRR_5,PT-VENN,Transglut_core k141_2954_2 745411.B3C1_08276 5.62e-54 170.0 2EP5W@1|root,33GSK@2|Bacteria,1NYMC@1224|Proteobacteria,1SW66@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_18628_1 218284.CCDN010000006_gene3730 1.51e-182 546.0 COG2247@1|root,COG2374@1|root,COG2247@2|Bacteria,COG2374@2|Bacteria,1VKCH@1239|Firmicutes,4IS68@91061|Bacilli,1ZS2A@1386|Bacillus 91061|Bacilli M Fn3 associated XK27_02140 - - ko:K07004 - - - - ko00000 - - - CHB_HEX_C_1,Exo_endo_phos,Fn3_assoc,Gram_pos_anchor,LTD,SLH k141_12747_1 566466.NOR53_3149 8.51e-27 107.0 COG1566@1|root,COG1566@2|Bacteria,1R50C@1224|Proteobacteria,1S9AT@1236|Gammaproteobacteria,1J9QW@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria V Protein of unknown function (DUF3667) - - - - - - - - - - - - DUF3667 k141_11485_1 666686.B1NLA3E_02240 3.91e-20 89.7 COG2244@1|root,COG2244@2|Bacteria,1VRYZ@1239|Firmicutes,4HV8Z@91061|Bacilli,1ZCGG@1386|Bacillus 91061|Bacilli S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid ykvU - - - - - - - - - - - MatE,Polysacc_synt,Polysacc_synt_C k141_11485_2 218284.CCDN010000002_gene2165 3.25e-32 124.0 COG0025@1|root,COG0025@2|Bacteria,1U8X3@1239|Firmicutes,4HBQR@91061|Bacilli,1ZQCD@1386|Bacillus 91061|Bacilli P Sodium/hydrogen exchanger family - - - - - - - - - - - - Na_H_Exchanger,TrkA_N k141_33982_1 745411.B3C1_14550 6.57e-49 169.0 COG2207@1|root,COG2207@2|Bacteria,1N8IV@1224|Proteobacteria,1SD2J@1236|Gammaproteobacteria,1J75F@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria K COG2207 AraC-type DNA-binding domain-containing proteins - - - - - - - - - - - - HTH_18,SnoaL_2 k141_25757_1 218284.CCDN010000001_gene225 2.63e-26 100.0 COG3874@1|root,COG3874@2|Bacteria,1V6H7@1239|Firmicutes,4HIG7@91061|Bacilli,1ZG9C@1386|Bacillus 91061|Bacilli S Sporulation protein YtfJ ytfJ - - - - - - - - - - - Spore_YtfJ k141_5545_2 1042377.AFPJ01000008_gene2001 8.86e-207 577.0 COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,1RNB5@1236|Gammaproteobacteria,46A8R@72275|Alteromonadaceae 1236|Gammaproteobacteria C CoA-transferase family III - - - - - - - - - - - - CoA_transf_3 k141_22036_1 218284.CCDN010000002_gene2785 2.76e-67 218.0 COG4870@1|root,COG4870@2|Bacteria,1TS2S@1239|Firmicutes,4HAGD@91061|Bacilli,1ZD2A@1386|Bacillus 91061|Bacilli O Repeat of unknown function (DUF346) - - - - - - - - - - - - DUF346 k141_30225_1 1274524.BSONL12_17319 4.26e-91 270.0 COG0035@1|root,COG0035@2|Bacteria,1TPMT@1239|Firmicutes,4H9Y0@91061|Bacilli,1ZASG@1386|Bacillus 91061|Bacilli F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate upp GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 ko:K00761 ko00240,ko01100,map00240,map01100 - R00966 RC00063 ko00000,ko00001,ko01000 - - iSB619.SA_RS11010 UPRTase k141_30225_2 1307436.PBF_05173 3.64e-81 250.0 COG0381@1|root,COG0381@2|Bacteria,1TQZT@1239|Firmicutes,4HBI3@91061|Bacilli,1ZCZG@1386|Bacillus 91061|Bacilli M Belongs to the UDP-N-acetylglucosamine 2-epimerase family mnaA - 5.1.3.14 ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 M00362 R00420 RC00290 ko00000,ko00001,ko00002,ko01000,ko01005 - - iSB619.SA_RS11005 Epimerase_2 k141_27073_1 1196031.ALEG01000015_gene5168 1.26e-50 165.0 COG1225@1|root,COG1225@2|Bacteria,1UMIN@1239|Firmicutes,4ITW0@91061|Bacilli,1ZSDJ@1386|Bacillus 91061|Bacilli O AhpC/TSA antioxidant enzyme - - - - - - - - - - - - AhpC-TSA_2 k141_35200_1 1279017.AQYJ01000023_gene3260 2.38e-210 588.0 COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,1RNID@1236|Gammaproteobacteria,46CEQ@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG2230 Cyclopropane fatty acid synthase and related methyltransferases cfa - 2.1.1.79 ko:K00574 - - - - ko00000,ko01000 - - - CMAS k141_35200_2 1042377.AFPJ01000045_gene2588 2.64e-69 214.0 COG3030@1|root,COG3030@2|Bacteria,1MZJJ@1224|Proteobacteria,1S8XU@1236|Gammaproteobacteria,467SJ@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein affecting phage T7 exclusion by the F plasmid fxsA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016021,GO:0031224,GO:0044425,GO:0044464,GO:0071944 - ko:K07113 - - - - ko00000 - - - FxsA k141_35200_3 1453501.JELR01000006_gene4 7.36e-54 169.0 COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,1S8YR@1236|Gammaproteobacteria,467S2@72275|Alteromonadaceae 1236|Gammaproteobacteria O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter groS GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010033,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0032991,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051704,GO:0061077,GO:0101031,GO:1990220 - ko:K04078 - - - - ko00000,ko03029,ko03110 - - - Cpn10 k141_35200_4 1279017.AQYJ01000023_gene3263 0.0 940.0 COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,1RMTB@1236|Gammaproteobacteria,4647Z@72275|Alteromonadaceae 1236|Gammaproteobacteria O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions groL GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0008144,GO:0008150,GO:0009266,GO:0009314,GO:0009405,GO:0009408,GO:0009628,GO:0009987,GO:0016032,GO:0016462,GO:0016465,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019058,GO:0019068,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0035821,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0044183,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0051817,GO:0052047,GO:0052212,GO:0061077,GO:0097159,GO:0097367,GO:0101031,GO:1901265,GO:1901363,GO:1990220 - ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 - - - Cpn60_TCP1 k141_35200_5 1395571.TMS3_0111280 1.25e-123 379.0 COG0515@1|root,COG0515@2|Bacteria,1MVEU@1224|Proteobacteria,1SYEH@1236|Gammaproteobacteria 1236|Gammaproteobacteria KLT serine threonine protein kinase - - 2.7.11.1 ko:K08884,ko:K11912 ko02025,ko03070,map02025,map03070 - - - ko00000,ko00001,ko01000,ko01001,ko02044 - - - Pkinase k141_20784_2 1279017.AQYJ01000027_gene1719 2.82e-66 226.0 COG0803@1|root,COG0803@2|Bacteria,1MY4H@1224|Proteobacteria,1S26I@1236|Gammaproteobacteria,46AMU@72275|Alteromonadaceae 1236|Gammaproteobacteria P Belongs to the bacterial solute-binding protein 9 family - - - - - - - - - - - - DUF4175 k141_37415_1 935836.JAEL01000101_gene4444 1.57e-28 103.0 2EK2J@1|root,33DT0@2|Bacteria,1VMKI@1239|Firmicutes,4HS9U@91061|Bacilli,1ZJJ0@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_37415_2 1131730.BAVI_25629 1.74e-12 66.2 29S0H@1|root,30D4U@2|Bacteria,1UAUP@1239|Firmicutes,4IM7H@91061|Bacilli,1ZJEE@1386|Bacillus 91061|Bacilli S Family of unknown function (DUF5345) - - - - - - - - - - - - DUF5345 k141_37415_3 1196031.ALEG01000039_gene1061 6.25e-85 255.0 COG1595@1|root,COG1595@2|Bacteria,1VB37@1239|Firmicutes,4HMZ2@91061|Bacilli,1ZCWY@1386|Bacillus 91061|Bacilli K Belongs to the sigma-70 factor family. ECF subfamily sigY - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4,Sigma70_r4_2 k141_18629_1 1453501.JELR01000001_gene3264 1.97e-179 516.0 COG0204@1|root,COG0204@2|Bacteria,1MWDY@1224|Proteobacteria,1RRXF@1236|Gammaproteobacteria,464IC@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG0477 Permeases of the major facilitator superfamily aas - 2.3.1.40,6.2.1.20 ko:K05939 ko00071,ko00564,map00071,map00564 - R01406,R04864 RC00014,RC00039,RC00041 ko00000,ko00001,ko01000 - - - Acyltransferase,MFS_1 k141_27836_1 1294265.JCM21738_210 4.11e-103 328.0 COG0699@1|root,COG0699@2|Bacteria,1TR0Q@1239|Firmicutes,4HBAC@91061|Bacilli,1ZAXM@1386|Bacillus 91061|Bacilli S Dynamin family ypbR GO:0000910,GO:0003674,GO:0003824,GO:0003924,GO:0005575,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022402,GO:0022607,GO:0031224,GO:0032506,GO:0044085,GO:0044425,GO:0051301,GO:0071840,GO:0090529 - - - - - - - - - - Dynamin_N k141_1758_1 1219076.N646_4547 1.31e-128 370.0 COG1073@1|root,COG1073@2|Bacteria,1MUCD@1224|Proteobacteria,1RPCZ@1236|Gammaproteobacteria,1XYUQ@135623|Vibrionales 135623|Vibrionales S X-Pro dipeptidyl-peptidase (S15 family) - - - ko:K06889 - - - - ko00000 - - - Peptidase_S15 k141_13962_1 1196324.A374_02944 5.6e-34 119.0 2CGTU@1|root,32Z9H@2|Bacteria,1VG36@1239|Firmicutes,4HNI4@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF3055) - - - - - - - - - - - - DUF3055 k141_13962_2 1385511.N783_04115 4.38e-14 66.6 2DZWK@1|root,32VKV@2|Bacteria,1VGZB@1239|Firmicutes,4HKJ4@91061|Bacilli,2YAQ0@289201|Pontibacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_2973_1 290397.Adeh_4175 2.94e-17 81.3 COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,42PTX@68525|delta/epsilon subdivisions,2WMQW@28221|Deltaproteobacteria,2YYFF@29|Myxococcales 28221|Deltaproteobacteria M Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria kdsB - 2.7.7.38 ko:K00979 ko00540,ko01100,map00540,map01100 M00063 R03351,R11396 RC00152,RC00910 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CTP_transf_3 k141_25787_1 218284.CCDN010000002_gene2075 7.71e-106 307.0 COG2032@1|root,COG2032@2|Bacteria,1V3HM@1239|Firmicutes,4IR7P@91061|Bacilli,1ZRS8@1386|Bacillus 91061|Bacilli P Destroys radicals which are normally produced within the cells and which are toxic to biological systems - - - - - - - - - - - - Sod_Cu k141_11509_1 1131730.BAVI_03824 1.93e-73 231.0 COG1879@1|root,COG1879@2|Bacteria,1TQZS@1239|Firmicutes,4HCUS@91061|Bacilli,1ZB0G@1386|Bacillus 91061|Bacilli G Periplasmic binding protein LacI transcriptional regulator - - - ko:K10439 ko02010,ko02030,map02010,map02030 M00212 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - Peripla_BP_4 k141_17277_1 1279017.AQYJ01000027_gene1563 2.33e-100 303.0 COG3705@1|root,COG3705@2|Bacteria,1MWIG@1224|Proteobacteria,1RPRQ@1236|Gammaproteobacteria,4649K@72275|Alteromonadaceae 1236|Gammaproteobacteria E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine hisZ - - ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002 - - - tRNA-synt_His k141_24470_1 1116375.VEJY3_06845 9.33e-171 491.0 COG0559@1|root,COG0559@2|Bacteria,1MVND@1224|Proteobacteria,1RQXD@1236|Gammaproteobacteria,1XUB9@135623|Vibrionales 135623|Vibrionales E Belongs to the binding-protein-dependent transport system permease family urtB - - ko:K11960 ko02010,map02010 M00323 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4.4,3.A.1.4.5 - - BPD_transp_2 k141_6668_1 218284.CCDN010000001_gene1764 2.21e-81 259.0 COG3276@1|root,COG3276@2|Bacteria,1TPQS@1239|Firmicutes,4HDD5@91061|Bacilli,1ZD2K@1386|Bacillus 91061|Bacilli J Selenocysteine-specific translation elongation factor selB - - ko:K03833 - - - - ko00000,ko03012 - - - GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3 k141_816_1 218284.CCDN010000001_gene1001 7.27e-122 356.0 COG2195@1|root,COG2195@2|Bacteria,1TP3A@1239|Firmicutes,4HA04@91061|Bacilli,1ZBSY@1386|Bacillus 91061|Bacilli E COG2195 Di- and tripeptidases yqjE - 3.4.11.14,3.4.11.4 ko:K01258,ko:K01263 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20,Peptidase_M28 k141_25945_1 1267533.KB906734_gene3770 5.95e-21 95.9 COG0215@1|root,COG0215@2|Bacteria,3Y2PW@57723|Acidobacteria,2JHIQ@204432|Acidobacteriia 204432|Acidobacteriia J Belongs to the class-I aminoacyl-tRNA synthetase family cysS - 6.1.1.16 ko:K01883 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_2,tRNA-synt_1e k141_29325_1 1385511.N783_03245 1.5e-84 261.0 COG3173@1|root,COG3173@2|Bacteria,1TUSS@1239|Firmicutes,4IJ0M@91061|Bacilli,2YB8W@289201|Pontibacillus 91061|Bacilli S Phosphotransferase enzyme family - - - - - - - - - - - - APH k141_3149_1 1121090.KB894704_gene1527 7.57e-89 265.0 COG2057@1|root,COG2057@2|Bacteria,1TNY5@1239|Firmicutes,4HBFR@91061|Bacilli,1ZB4Q@1386|Bacillus 91061|Bacilli I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit scoB - 2.8.3.5 ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 - R00410 RC00014 ko00000,ko00001,ko01000 - - - CoA_trans k141_3149_2 218284.CCDN010000001_gene1028 4.27e-153 431.0 COG1788@1|root,COG1788@2|Bacteria,1V21Q@1239|Firmicutes,4HB3E@91061|Bacilli,1ZCXP@1386|Bacillus 91061|Bacilli I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit scoA - 2.8.3.5 ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 - R00410 RC00014 ko00000,ko00001,ko01000 - - - CoA_trans k141_27329_1 698769.JFBD01000095_gene3070 3.13e-32 115.0 COG0454@1|root,COG0456@2|Bacteria,1VD0V@1239|Firmicutes,4HM2C@91061|Bacilli 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10 k141_22301_1 218284.CCDN010000002_gene2858 5.05e-75 243.0 COG1657@1|root,COG1657@2|Bacteria,1TRRG@1239|Firmicutes,4HA2Q@91061|Bacilli,1ZBBW@1386|Bacillus 91061|Bacilli I COG1657 Squalene cyclase sqhC - 4.2.1.137 ko:K18115 - - - - ko00000,ko01000 - - - SQHop_cyclase_C,SQHop_cyclase_N k141_35406_2 218284.CCDN010000002_gene2909 1.76e-18 84.0 COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HA0V@91061|Bacilli,1ZBTK@1386|Bacillus 91061|Bacilli O Belongs to the ClpA ClpB family clpE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03697,ko:K04086 - - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,UVR k141_36335_2 218284.CCDN010000001_gene1104 2.29e-18 80.5 28J08@1|root,2Z8XG@2|Bacteria,1V177@1239|Firmicutes,4HCWC@91061|Bacilli,1ZCRV@1386|Bacillus 91061|Bacilli - - yphF - - - - - - - - - - - DUF3939 k141_27960_1 240302.BN982_03285 1.24e-129 385.0 COG1574@1|root,COG1574@2|Bacteria,1TQ6G@1239|Firmicutes,4HC54@91061|Bacilli,3NDTX@45667|Halobacillus 91061|Bacilli S Amidohydrolase family - - - - - - - - - - - - Amidohydro_3 k141_32833_1 218284.CCDN010000001_gene1050 5.19e-101 304.0 COG0019@1|root,COG0019@2|Bacteria,1TPE9@1239|Firmicutes,4H9XW@91061|Bacilli,1ZD43@1386|Bacillus 91061|Bacilli E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine lysA - 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N,Orn_DAP_Arg_deC k141_958_1 1122194.AUHU01000004_gene1446 1.06e-144 421.0 COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,1RPZC@1236|Gammaproteobacteria,465AN@72275|Alteromonadaceae 1236|Gammaproteobacteria J exonuclease of the beta-lactamase fold involved in RNA processing - - - ko:K07576 - - - - ko00000 - - - Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL k141_958_2 935863.AWZR01000004_gene411 1.81e-50 172.0 COG0462@1|root,COG0462@2|Bacteria,1MUV7@1224|Proteobacteria,1RY55@1236|Gammaproteobacteria,1X42K@135614|Xanthomonadales 135614|Xanthomonadales EF Belongs to the ribose-phosphate pyrophosphokinase family - - 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - Pribosyltran,Pribosyltran_N k141_23646_1 1330700.JQNC01000003_gene1536 2.02e-14 75.1 COG0500@1|root,COG2226@2|Bacteria,1WIUM@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) menG - 2.1.1.163,2.1.1.201 ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116,M00117 R04990,R04993,R06859,R08774,R09736 RC00003,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000 - - - Ubie_methyltran k141_22302_1 1307436.PBF_12512 7.14e-21 89.7 COG1388@1|root,COG1388@2|Bacteria,1V8A5@1239|Firmicutes,4HIV2@91061|Bacilli,1ZG8Q@1386|Bacillus 91061|Bacilli M Lysin motif ypbE - - - - - - - - - - - LysM k141_22302_2 218284.CCDN010000001_gene1076 8.44e-39 134.0 2EENU@1|root,338GN@2|Bacteria,1VK1A@1239|Firmicutes,4HNX3@91061|Bacilli,1ZC57@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2663) ypbF - - - - - - - - - - - DUF2663 k141_25946_1 218284.CCDN010000002_gene2003 1.17e-201 564.0 COG2224@1|root,COG2224@2|Bacteria,1TP1U@1239|Firmicutes,4HBBD@91061|Bacilli,1ZBPW@1386|Bacillus 91061|Bacilli C Isocitrate lyase aceA - 4.1.3.1 ko:K01637 ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200 M00012 R00479 RC00311,RC00313 ko00000,ko00001,ko00002,ko01000 - - - ICL k141_16270_1 1137799.GZ78_13580 6.62e-133 399.0 COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,1RPNE@1236|Gammaproteobacteria,1XIUK@135619|Oceanospirillales 135619|Oceanospirillales I AMP-binding enzyme - - - - - - - - - - - - AMP-binding k141_16270_2 314287.GB2207_11213 3.12e-54 176.0 COG5424@1|root,COG5424@2|Bacteria,1QVK0@1224|Proteobacteria,1T2JB@1236|Gammaproteobacteria,1J4R9@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H Iron-containing redox enzyme - - - - - - - - - - - - Haem_oxygenas_2 k141_23647_2 1453501.JELR01000002_gene95 3.87e-40 134.0 COG2142@1|root,COG2142@2|Bacteria,1MZR9@1224|Proteobacteria,1S9TS@1236|Gammaproteobacteria,467WQ@72275|Alteromonadaceae 1236|Gammaproteobacteria C Membrane-anchoring subunit of succinate dehydrogenase (SDH) sdhD GO:0000104,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0016999,GO:0017004,GO:0017144,GO:0019752,GO:0020037,GO:0022607,GO:0022900,GO:0032991,GO:0034622,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0065003,GO:0070469,GO:0070470,GO:0071704,GO:0071840,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901363,GO:1902494,GO:1990204 - ko:K00242 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173 R02164 RC00045 ko00000,ko00001,ko00002 - - e_coli_core.b0722,iAF1260.b0722,iAPECO1_1312.APECO1_1356,iB21_1397.B21_00671,iBWG_1329.BWG_0581,iE2348C_1286.E2348C_0602,iEC042_1314.EC042_0740,iECABU_c1320.ECABU_c07680,iECBD_1354.ECBD_2938,iECB_1328.ECB_00682,iECDH10B_1368.ECDH10B_0789,iECDH1ME8569_1439.ECDH1ME8569_0681,iECD_1391.ECD_00682,iECED1_1282.ECED1_0692,iECIAI1_1343.ECIAI1_0696,iECIAI39_1322.ECIAI39_0680,iECNA114_1301.ECNA114_0658,iECO103_1326.ECO103_0716,iECO111_1330.ECO111_0739,iECO26_1355.ECO26_0783,iECOK1_1307.ECOK1_0722,iECP_1309.ECP_0734,iECS88_1305.ECS88_0748,iECSE_1348.ECSE_0782,iECSF_1327.ECSF_0655,iECUMN_1333.ECUMN_0800,iECW_1372.ECW_m0777,iEKO11_1354.EKO11_3157,iETEC_1333.ETEC_0733,iEcDH1_1363.EcDH1_2913,iEcE24377_1341.EcE24377A_0749,iEcHS_1320.EcHS_A0770,iEcSMS35_1347.EcSMS35_0735,iEcolC_1368.EcolC_2933,iJO1366.b0722,iJR904.b0722,iLF82_1304.LF82_2100,iNRG857_1313.NRG857_03215,iSBO_1134.SBO_0580,iSDY_1059.SDY_0660,iSFV_1184.SFV_0613,iSF_1195.SF0575,iSFxv_1172.SFxv_0634,iSSON_1240.SSON_0673,iS_1188.S0588,iUMN146_1321.UM146_14010,iUMNK88_1353.UMNK88_758,iUTI89_1310.UTI89_C0718,iWFL_1372.ECW_m0777,iY75_1357.Y75_RS03755,ic_1306.c0800 Sdh_cyt k141_10426_2 1423321.AS29_13970 1.68e-112 332.0 29SNM@1|root,30DU7@2|Bacteria,1V3Z9@1239|Firmicutes,4HHKX@91061|Bacilli,1ZG30@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2785) - - - - - - - - - - - - DUF2785 k141_6884_1 926569.ANT_13690 5.32e-105 317.0 COG2407@1|root,COG2407@2|Bacteria,2G84V@200795|Chloroflexi 200795|Chloroflexi G L-fucose isomerase, C-terminal domain - - - - - - - - - - - - Fucose_iso_C k141_29328_1 1423321.AS29_13665 2.28e-125 363.0 COG2378@1|root,COG2378@2|Bacteria,1U968@1239|Firmicutes,4HB5H@91061|Bacilli,1ZQBB@1386|Bacillus 91061|Bacilli K Transcriptional regulator yobV9 - - - - - - - - - - - HTH_11,WYL k141_18920_1 218284.CCDN010000008_gene4180 9.56e-88 268.0 COG0477@1|root,COG2814@2|Bacteria,1TPJ6@1239|Firmicutes,4HAGJ@91061|Bacilli,1ZBPE@1386|Bacillus 91061|Bacilli EGP Major facilitator superfamily yttB - - - - - - - - - - - MFS_1 k141_27961_1 218284.CCDN010000001_gene1478 1.88e-17 79.3 COG2138@1|root,COG2138@2|Bacteria,1TRDV@1239|Firmicutes,4H9RT@91061|Bacilli,1ZGH1@1386|Bacillus 91061|Bacilli S Sirohydrochlorin ferrochelatase sirB - 4.99.1.4 ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R02864 RC01012 ko00000,ko00001,ko00002,ko01000 - - - CbiX k141_27961_2 218284.CCDN010000001_gene1477 1.48e-98 291.0 COG0007@1|root,COG0007@2|Bacteria,1TQNH@1239|Firmicutes,4HBB7@91061|Bacilli,1ZBV1@1386|Bacillus 91061|Bacilli H Belongs to the precorrin methyltransferase family cobA GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107 ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R03194 RC00003,RC00871 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU15610 TP_methylase k141_35408_1 1307436.PBF_09262 3.9e-126 381.0 COG2409@1|root,COG2409@2|Bacteria,1TQ7C@1239|Firmicutes,4H9XX@91061|Bacilli,1ZQAJ@1386|Bacillus 91061|Bacilli S MMPL domain protein - - - ko:K06994 - - - - ko00000 - - - MMPL k141_23649_1 1453501.JELR01000001_gene3063 3.33e-58 200.0 COG0501@1|root,COG0501@2|Bacteria,1MVU4@1224|Proteobacteria,1RPJ5@1236|Gammaproteobacteria,46584@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG0501 Zn-dependent protease with chaperone function htpX - - ko:K03799 - M00743 - - ko00000,ko00002,ko01000,ko01002 - - - Peptidase_M48 k141_18921_1 218284.CCDN010000002_gene2875 3.86e-124 366.0 COG1053@1|root,COG1053@2|Bacteria,1TPAR@1239|Firmicutes,4HAXN@91061|Bacilli,1ZBU7@1386|Bacillus 91061|Bacilli C COG1053 Succinate dehydrogenase fumarate reductase, flavoprotein subunit - - - ko:K13796 - - - - ko00000 - - - FAD_binding_2 k141_35409_1 1294265.JCM21738_896 2.07e-83 257.0 COG4191@1|root,COG4191@2|Bacteria,1VTMF@1239|Firmicutes,4HV0V@91061|Bacilli,1ZCNW@1386|Bacillus 91061|Bacilli T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA k141_11686_1 1141663.OOC_19072 8.15e-78 248.0 COG1972@1|root,COG1972@2|Bacteria,1MXXX@1224|Proteobacteria,1RMBX@1236|Gammaproteobacteria,3Z73Y@586|Providencia 1236|Gammaproteobacteria F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family nupX GO:0003674,GO:0005215,GO:0005337,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0015858,GO:0015931,GO:0015932,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:1901264,GO:1901505,GO:1901642 - ko:K03317 - - - - ko00000 2.A.41 - - Gate,Nucleos_tra2_C,Nucleos_tra2_N k141_37542_1 1279017.AQYJ01000028_gene2321 2.58e-46 169.0 COG2982@1|root,COG2982@2|Bacteria,1MUME@1224|Proteobacteria,1RNPC@1236|Gammaproteobacteria,464KK@72275|Alteromonadaceae 1236|Gammaproteobacteria M Domain of Unknown Function (DUF748) - - - - - - - - - - - - DUF748,OmpA k141_29330_1 1042377.AFPJ01000024_gene746 4.13e-74 229.0 COG3217@1|root,COG3217@2|Bacteria,1MXN2@1224|Proteobacteria,1RMN7@1236|Gammaproteobacteria,4676N@72275|Alteromonadaceae 1236|Gammaproteobacteria C Fe-S protein ycbX GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009636,GO:0009987,GO:0019748,GO:0042221,GO:0044237,GO:0044248,GO:0050896,GO:0098754 - ko:K07140 - - - - ko00000 - - - FAD_binding_6,Fer2,MOSC,MOSC_N,NAD_binding_1 k141_23650_1 1347086.CCBA010000010_gene1735 1.19e-103 312.0 COG2267@1|root,COG2267@2|Bacteria,1V0IY@1239|Firmicutes,4HBP3@91061|Bacilli,1ZFXU@1386|Bacillus 91061|Bacilli I Alpha beta hydrolase - - - - - - - - - - - - Abhydrolase_1,Hydrolase_4 k141_20933_1 1236542.BALM01000015_gene1100 3.09e-05 51.2 COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,1S64Q@1236|Gammaproteobacteria,2QAQJ@267890|Shewanellaceae 1236|Gammaproteobacteria S Competence protein gntX GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0015976,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 - - - - - - - - - - Pribosyltran k141_25949_1 218284.CCDN010000002_gene2197 3.03e-108 328.0 COG5373@1|root,COG5373@2|Bacteria,1UXZY@1239|Firmicutes,4HEQP@91061|Bacilli,1ZBHN@1386|Bacillus 91061|Bacilli S Predicted membrane protein (DUF2339) - - - - - - - - - - - - DUF2339 k141_16284_1 1042377.AFPJ01000035_gene2647 6.94e-58 183.0 2E5XZ@1|root,330MS@2|Bacteria,1NBN8@1224|Proteobacteria,1SCZT@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_18964_1 218284.CCDN010000005_gene3198 4.12e-22 92.4 28PM4@1|root,2ZCA8@2|Bacteria,1V1PA@1239|Firmicutes,4HFNN@91061|Bacilli,1ZG8T@1386|Bacillus 91061|Bacilli S YtkA-like ytkA - - - - - - - - - - - PKD,YtkA k141_6926_1 1042377.AFPJ01000008_gene2022 6.12e-42 147.0 COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,1RNB5@1236|Gammaproteobacteria,469JA@72275|Alteromonadaceae 1236|Gammaproteobacteria C CoA-transferase family III - - - - - - - - - - - - CoA_transf_3 k141_6926_2 1042377.AFPJ01000008_gene2021 1.4e-261 719.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RMMJ@1236|Gammaproteobacteria,46CUH@72275|Alteromonadaceae 1236|Gammaproteobacteria C Acyl-CoA dehydrogenase, C-terminal domain - - - ko:K18244 - - - - ko00000,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_6926_3 1042377.AFPJ01000008_gene2020 4.53e-120 343.0 COG2030@1|root,COG2030@2|Bacteria,1MW4N@1224|Proteobacteria,1S43F@1236|Gammaproteobacteria,46A73@72275|Alteromonadaceae 1236|Gammaproteobacteria I MaoC like domain - - 4.2.1.56 ko:K18290 ko00660,map00660 - R02491 RC00730 ko00000,ko00001,ko01000 - - - MaoC_dehydratas k141_6926_4 1050202.KB913024_gene614 1.13e-11 69.7 COG2301@1|root,COG2301@2|Bacteria,2GK5J@201174|Actinobacteria,408P3@622450|Actinopolysporales 201174|Actinobacteria G HpcH/HpaI aldolase/citrate lyase family mcl1 - 4.1.3.34,5.4.99.63 ko:K01644,ko:K14447 ko00630,ko01120,ko01200,ko02020,map00630,map01120,map01200,map02020 M00373 R00362,R09292 RC00067,RC01118,RC02835 ko00000,ko00001,ko00002,ko01000 - - - HpcH_HpaI k141_7939_1 1232683.ADIMK_3151 3.25e-110 320.0 COG1230@1|root,COG1230@2|Bacteria,1MUSS@1224|Proteobacteria,1RQ3M@1236|Gammaproteobacteria,46721@72275|Alteromonadaceae 1236|Gammaproteobacteria P Cation efflux family - - - - - - - - - - - - Cation_efflux k141_7939_4 675806.VII_000722 2.93e-48 170.0 2FBG7@1|root,343MJ@2|Bacteria,1P3N2@1224|Proteobacteria,1SS0Y@1236|Gammaproteobacteria,1Y1TB@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_37561_1 1453501.JELR01000002_gene1471 4.39e-102 306.0 COG0845@1|root,COG0845@2|Bacteria,1PEVY@1224|Proteobacteria,1RPEQ@1236|Gammaproteobacteria,465PN@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - - - - - - - - - - Biotin_lipoyl_2,HlyD_3 k141_1897_1 218284.CCDN010000004_gene3134 2.78e-176 509.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,1ZBIW@1386|Bacillus 91061|Bacilli V COG1132 ABC-type multidrug transport system, ATPase and permease components yheH GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702 - ko:K18217,ko:K18890 ko02010,map02010 M00635,M00707 - - ko00000,ko00001,ko00002,ko01504,ko02000 3.A.1,3.A.1.106.13,3.A.1.106.5 - - ABC_membrane,ABC_tran k141_22336_1 671143.DAMO_0390 7.07e-56 189.0 COG0389@1|root,COG0389@2|Bacteria,2NP5S@2323|unclassified Bacteria 2|Bacteria L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII dinB - 2.7.7.7 ko:K02346,ko:K14161 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH k141_24657_1 1279017.AQYJ01000029_gene3457 1.81e-69 227.0 COG3067@1|root,COG3067@2|Bacteria,1MV0F@1224|Proteobacteria,1RPE3@1236|Gammaproteobacteria,464PD@72275|Alteromonadaceae 1236|Gammaproteobacteria P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons nhaB GO:0003674,GO:0005215,GO:0005451,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0006873,GO:0006885,GO:0008150,GO:0008324,GO:0009987,GO:0010035,GO:0010038,GO:0010226,GO:0015075,GO:0015077,GO:0015078,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015491,GO:0015672,GO:0016020,GO:0019725,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030004,GO:0030641,GO:0034220,GO:0035725,GO:0042221,GO:0042592,GO:0044464,GO:0045851,GO:0046873,GO:0048878,GO:0050801,GO:0050896,GO:0051179,GO:0051234,GO:0051452,GO:0051453,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0098771,GO:0099516,GO:1902600 - ko:K03314 - - - - ko00000,ko02000 2.A.34.1 - iECP_1309.ECP_1229,iLF82_1304.LF82_1485,iNRG857_1313.NRG857_06055,iUTI89_1310.UTI89_C1372 NhaB k141_19938_1 574375.BAGA_04200 6.02e-48 164.0 COG1092@1|root,COG1092@2|Bacteria,1TRAJ@1239|Firmicutes,4HAA1@91061|Bacilli,1ZBVG@1386|Bacillus 91061|Bacilli J Methyltransferase ywbD - 2.1.1.191 ko:K06969 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_SAM k141_10441_1 1453501.JELR01000002_gene116 2.28e-96 304.0 COG1629@1|root,COG4771@2|Bacteria,1MUNK@1224|Proteobacteria,1RN9S@1236|Gammaproteobacteria,464ZY@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_5719_4 218284.CCDN010000007_gene3940 8.15e-155 444.0 COG1078@1|root,COG1078@2|Bacteria,1TPVB@1239|Firmicutes,4HAX8@91061|Bacilli,1ZBRB@1386|Bacillus 91061|Bacilli S COG1078 HD superfamily phosphohydrolases ywfO GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 - ko:K06885 - - - - ko00000 - - - HD k141_9347_2 1453501.JELR01000002_gene511 4.89e-61 203.0 COG2133@1|root,COG2133@2|Bacteria,1MVK5@1224|Proteobacteria,1RPE8@1236|Gammaproteobacteria,4665U@72275|Alteromonadaceae 1236|Gammaproteobacteria G COG2133 Glucose sorbosone dehydrogenases - - - - - - - - - - - - GSDH k141_7940_2 218284.CCDN010000007_gene3986 3.75e-74 234.0 COG0840@1|root,COG0840@2|Bacteria,1TPI1@1239|Firmicutes,4HADY@91061|Bacilli,1ZD20@1386|Bacillus 91061|Bacilli NT Chemotaxis mcpA - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal k141_6927_1 1313301.AUGC01000011_gene1165 1.26e-24 100.0 COG0463@1|root,COG0463@2|Bacteria,4NGJK@976|Bacteroidetes 976|Bacteroidetes M Protein of unknown function (DUF4254) - - - - - - - - - - - - DUF4254 k141_11707_1 1294265.JCM21738_5393 1.94e-155 456.0 COG2183@1|root,COG2183@2|Bacteria,1TPFE@1239|Firmicutes,4HAGY@91061|Bacilli,1ZC3T@1386|Bacillus 91061|Bacilli K COG2183 Transcriptional accessory protein tex - - ko:K06959 - - - - ko00000 - - - HHH_3,S1,Tex_N,Tex_YqgF k141_25984_1 42565.FP66_00835 9.77e-71 213.0 2CCJF@1|root,32RVW@2|Bacteria,1MZUN@1224|Proteobacteria,1SQ8K@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_25984_2 768066.HELO_1493 1.41e-20 86.3 COG1309@1|root,COG1309@2|Bacteria,1R67Z@1224|Proteobacteria,1SYMN@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N k141_19939_2 546274.EIKCOROL_00143 6.46e-12 66.2 COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,2VH82@28216|Betaproteobacteria,2KPF3@206351|Neisseriales 206351|Neisseriales P Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA - - - ko:K03498 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkH k141_24658_1 1246484.D479_15117 4.1e-110 325.0 COG0116@1|root,COG0116@2|Bacteria,1TP0X@1239|Firmicutes,4HBKY@91061|Bacilli,3NDMR@45667|Halobacillus 91061|Bacilli L THUMP ypsC GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 - ko:K07444 - - - - ko00000,ko01000 - - - THUMP,UPF0020 k141_15046_1 1116375.VEJY3_13855 7.23e-53 173.0 COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,1RMI0@1236|Gammaproteobacteria,1XTNY@135623|Vibrionales 135623|Vibrionales U MSHA biogenesis protein MshM mshM - - ko:K12283 - - - - ko00000,ko02044 - - - AAA_22 k141_15046_2 1116375.VEJY3_13860 0.0 894.0 COG1450@1|root,COG1450@2|Bacteria,1MVNC@1224|Proteobacteria,1RQGJ@1236|Gammaproteobacteria,1XTAX@135623|Vibrionales 135623|Vibrionales NU Secretin N-terminal domain mshL - - ko:K12282 - - - - ko00000,ko02044 - - - Secretin,Secretin_N_2 k141_15046_3 1280001.BAOA01000048_gene1820 1.35e-46 152.0 2DR7A@1|root,33AIK@2|Bacteria,1NGEC@1224|Proteobacteria,1SGK6@1236|Gammaproteobacteria,1XYWI@135623|Vibrionales 135623|Vibrionales S MSHA biogenesis protein MshK mshK - - ko:K12281 - - - - ko00000,ko02044 - - - - k141_15046_4 1219076.N646_1797 6.12e-61 192.0 COG3167@1|root,COG3167@2|Bacteria,1N1KE@1224|Proteobacteria,1S8XS@1236|Gammaproteobacteria,1XWVJ@135623|Vibrionales 135623|Vibrionales NU Pilus assembly protein, PilO mshJ - - ko:K12280 - - - - ko00000,ko02044 - - - PilO,T2SSM k141_23677_1 218284.CCDN010000001_gene647 5.57e-122 352.0 2C7CE@1|root,30872@2|Bacteria,1V67M@1239|Firmicutes,4HHGE@91061|Bacilli,1ZDZH@1386|Bacillus 91061|Bacilli S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) - - - ko:K06345 - - - - ko00000 - - - Spore_YhcN_YlaJ k141_32873_1 1118235.CAJH01000019_gene1039 3.14e-32 128.0 COG2199@1|root,COG3706@2|Bacteria,1MX83@1224|Proteobacteria,1RMRP@1236|Gammaproteobacteria,1X7P0@135614|Xanthomonadales 135614|Xanthomonadales T Cache domain - - - - - - - - - - - - GGDEF,dCache_1 k141_27981_1 1294265.JCM21738_1290 1.38e-70 216.0 COG0425@1|root,COG0607@1|root,COG0425@2|Bacteria,COG0607@2|Bacteria,1V1GU@1239|Firmicutes,4HFR8@91061|Bacilli,1ZAVN@1386|Bacillus 91061|Bacilli OP Belongs to the sulfur carrier protein TusA family yrkF - - - - - - - - - - - Rhodanese,TusA k141_9348_1 981383.AEWH01000020_gene2471 4.18e-21 90.9 COG0313@1|root,COG0313@2|Bacteria,1TP6U@1239|Firmicutes,4HAH8@91061|Bacilli 91061|Bacilli H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA rsmI GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 2.1.1.198 ko:K07056 - - - - ko00000,ko01000,ko03009 - - - TP_methylase k141_15047_1 1313172.YM304_32070 3.93e-31 120.0 COG2021@1|root,COG2021@2|Bacteria 2|Bacteria E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6,Hydrolase_4 k141_16285_3 187303.BN69_2422 5.37e-19 80.1 COG0599@1|root,COG0599@2|Bacteria 2|Bacteria S peroxiredoxin activity - - 4.1.1.44 ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 - R03470 RC00938 ko00000,ko00001,ko01000 - - - CMD k141_23678_1 218284.CCDN010000002_gene2731 8.98e-80 254.0 COG3711@1|root,COG3711@2|Bacteria,1TQT1@1239|Firmicutes,4HABH@91061|Bacilli,1ZBYI@1386|Bacillus 91061|Bacilli K transcriptional regulator, MtlR mtlR - - ko:K03483 - - - - ko00000,ko03000 - - - HTH_11,Mga,PRD,PTS_EIIA_2,PTS_IIB k141_23678_2 218284.CCDN010000002_gene2732 9.12e-78 241.0 COG0246@1|root,COG0246@2|Bacteria,1TPZU@1239|Firmicutes,4H9S3@91061|Bacilli,1ZD4H@1386|Bacillus 91061|Bacilli G COG0246 Mannitol-1-phosphate altronate dehydrogenases mtlD GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006059,GO:0006066,GO:0008150,GO:0008152,GO:0008926,GO:0009056,GO:0009987,GO:0016052,GO:0016491,GO:0016614,GO:0016616,GO:0019400,GO:0019405,GO:0019407,GO:0019592,GO:0019594,GO:0019751,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046164,GO:0046174,GO:0055114,GO:0071704,GO:1901575,GO:1901615,GO:1901616 1.1.1.17 ko:K00009 ko00051,map00051 - R02703 RC00085 ko00000,ko00001,ko01000 - - - Mannitol_dh,Mannitol_dh_C k141_27982_1 1131730.BAVI_17702 2.27e-29 120.0 COG1595@1|root,COG1595@2|Bacteria,1U9I0@1239|Firmicutes,4IJNF@91061|Bacilli,1ZC9D@1386|Bacillus 91061|Bacilli K Domain of unknown function (DUF4179) - - - - - - - - - - - - DUF4179,Sigma70_r4,Sigma70_r4_2,zf-HC2 k141_15048_1 1278073.MYSTI_00248 1.73e-52 175.0 COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,42NTG@68525|delta/epsilon subdivisions,2X5CT@28221|Deltaproteobacteria,2YV0W@29|Myxococcales 28221|Deltaproteobacteria Q ABC transporter - - - ko:K02065 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - ABC_tran k141_6929_1 1042377.AFPJ01000036_gene1141 2.75e-132 387.0 COG1305@1|root,COG1305@2|Bacteria,1R72E@1224|Proteobacteria,1S1BR@1236|Gammaproteobacteria 1236|Gammaproteobacteria E COG1305 Transglutaminase-like enzymes - - - - - - - - - - - - Transglut_core k141_16286_2 1453501.JELR01000002_gene121 9.42e-43 149.0 COG2055@1|root,COG2055@2|Bacteria,1MWQY@1224|Proteobacteria,1RSKW@1236|Gammaproteobacteria,4685W@72275|Alteromonadaceae 1236|Gammaproteobacteria C Malate/L-lactate dehydrogenase - - - - - - - - - - - - Ldh_2 k141_35432_1 223926.28805602 4.06e-57 189.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,1RMT8@1236|Gammaproteobacteria,1XT7Z@135623|Vibrionales 135623|Vibrionales F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth guaB - 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 - - - CBS,IMPDH k141_35432_2 1116375.VEJY3_02825 0.0 1044.0 COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,1RP81@1236|Gammaproteobacteria,1XTWC@135623|Vibrionales 135623|Vibrionales F Catalyzes the synthesis of GMP from XMP guaA GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase,GMP_synt_C,NAD_synthase k141_35432_3 1051646.VITU9109_09077 0.0 978.0 COG3979@1|root,COG3979@2|Bacteria,1R3XZ@1224|Proteobacteria,1RNEE@1236|Gammaproteobacteria,1XT4J@135623|Vibrionales 135623|Vibrionales E protein contain chitin-binding domain type 3 VV0777 - - - - - - - - - - - CBM_5_12,Glyco_hydro_19 k141_35432_5 1116375.VEJY3_02830 2.44e-134 381.0 COG1584@1|root,COG1584@2|Bacteria,1N3HP@1224|Proteobacteria,1RMRK@1236|Gammaproteobacteria,1XTVE@135623|Vibrionales 135623|Vibrionales S GPR1/FUN34/yaaH family yaaH - - ko:K07034 - - - - ko00000 - - - Grp1_Fun34_YaaH k141_35432_6 1116375.VEJY3_02835 2.15e-199 556.0 COG0560@1|root,COG0560@2|Bacteria,1MW38@1224|Proteobacteria,1RQAT@1236|Gammaproteobacteria,1XTC0@135623|Vibrionales 135623|Vibrionales E haloacid dehalogenase-like hydrolase - - - - - - - - - - - - HAD k141_11708_2 1042377.AFPJ01000037_gene2964 1.05e-91 271.0 COG0671@1|root,COG0671@2|Bacteria,1RJ1T@1224|Proteobacteria,1SAU1@1236|Gammaproteobacteria,466ER@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG0671 Membrane-associated phospholipid phosphatase - - 3.6.1.27 ko:K19302 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - PAP2 k141_7970_6 1219076.N646_0249 2e-60 186.0 COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,1S46A@1236|Gammaproteobacteria,1XXXW@135623|Vibrionales 135623|Vibrionales J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance rplY GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02897 ko03010,map03010 M00178 - - ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L25p k141_7970_7 1116375.VEJY3_05835 0.0 993.0 COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,1RPX3@1236|Gammaproteobacteria,1XVPI@135623|Vibrionales 135623|Vibrionales F 5'-nucleotidase, C-terminal domain - - 3.1.3.5,3.6.1.45 ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - 5_nucleotid_C,Metallophos k141_10565_1 1294265.JCM21738_4217 7.59e-89 270.0 COG1250@1|root,COG1250@2|Bacteria,1TR8J@1239|Firmicutes,4H9XN@91061|Bacilli,1ZATV@1386|Bacillus 91061|Bacilli I 3-hydroxyacyl-CoA dehydrogenase fadN - 1.1.1.35 ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 M00087 R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU32840 3HCDH,3HCDH_N,ECH_1 k141_28183_1 1453501.JELR01000002_gene1394 4.37e-138 408.0 COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,1RSG9@1236|Gammaproteobacteria,464W2@72275|Alteromonadaceae 1236|Gammaproteobacteria E aminopeptidase pepN - - - - - - - - - - - Leuk-A4-hydro_C,Peptidase_M1 k141_17602_1 1347086.CCBA010000014_gene706 6.01e-317 875.0 COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,4HAB8@91061|Bacilli,1ZBS4@1386|Bacillus 91061|Bacilli J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome fusA - - ko:K02355 - - - - ko00000,ko03012,ko03029 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 k141_17602_4 1294265.JCM21738_4166 3.43e-24 92.4 COG1358@1|root,COG1358@2|Bacteria,1VFD8@1239|Firmicutes,4HNXS@91061|Bacilli,1ZIU6@1386|Bacillus 91061|Bacilli J Belongs to the eukaryotic ribosomal protein eL8 family rplGB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K07590 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L7Ae k141_35658_1 935836.JAEL01000097_gene3430 5.16e-97 291.0 2C5HJ@1|root,2Z812@2|Bacteria,1TQQ6@1239|Firmicutes,4HA3F@91061|Bacilli,1ZCGB@1386|Bacillus 91061|Bacilli S Tetraprenyl-beta-curcumene synthase ytpB - 4.2.3.130 ko:K16188 - - R10009 RC02994 ko00000,ko01000 - - - DUF2600 k141_21123_1 441769.ABFU01000028_gene1102 1.65e-55 183.0 COG1108@1|root,COG1108@2|Bacteria,1TPZB@1239|Firmicutes,4HBD7@91061|Bacilli,1ZAY6@1386|Bacillus 91061|Bacilli P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components' mntD GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0010035,GO:0010038,GO:0010043,GO:0016020,GO:0042221,GO:0044464,GO:0050896,GO:0071944 - ko:K11709,ko:K19976 ko02010,map02010 M00319,M00792 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15,3.A.1.15.15 - - ABC-3 k141_20170_2 702450.CUW_1776 2.72e-62 196.0 COG0189@1|root,COG0189@2|Bacteria,1TRXK@1239|Firmicutes 1239|Firmicutes HJ YheC/D like ATP-grasp - - - - - - - - - - - - ATPgrasp_YheCD k141_24900_1 1279017.AQYJ01000027_gene1962 1.53e-86 272.0 COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,1RMGJ@1236|Gammaproteobacteria,46A3P@72275|Alteromonadaceae 1236|Gammaproteobacteria Q COG1233 Phytoene dehydrogenase and related proteins - - 1.3.99.23 ko:K09516 ko00830,map00830 - R07163 RC01835 ko00000,ko00001,ko01000 - - - Amino_oxidase,FAD_binding_6,NAD_binding_1,NAD_binding_8 k141_24900_2 1236542.BALM01000011_gene3909 1.18e-10 60.1 2EFJH@1|root,339BV@2|Bacteria,1N9HI@1224|Proteobacteria,1SEHQ@1236|Gammaproteobacteria,2QCU2@267890|Shewanellaceae 1236|Gammaproteobacteria S Superinfection immunity protein - - - - - - - - - - - - Imm_superinfect k141_29601_1 40373.F991_01382 0.000891 45.8 COG4253@1|root,COG4253@2|Bacteria,1N8RR@1224|Proteobacteria,1SEXV@1236|Gammaproteobacteria,3NNZR@468|Moraxellaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_13060_1 1042377.AFPJ01000030_gene492 1.77e-86 264.0 COG0730@1|root,COG0730@2|Bacteria,1QRFH@1224|Proteobacteria,1RRFY@1236|Gammaproteobacteria,465YS@72275|Alteromonadaceae 1236|Gammaproteobacteria S Sulfite exporter TauE/SafE - - - - - - - - - - - - TauE k141_13060_2 28072.Nos7524_0715 6.18e-15 79.0 COG0665@1|root,COG0665@2|Bacteria,1GHDF@1117|Cyanobacteria,1HSEG@1161|Nostocales 1117|Cyanobacteria E Tryptophan halogenase - - 1.14.19.9 ko:K14266 ko00404,ko01130,map00404,map01130 M00789,M00790 R09570 RC00949 ko00000,ko00001,ko00002,ko01000 - - - Trp_halogenase k141_35659_1 1453501.JELR01000002_gene1307 8.43e-78 232.0 COG1188@1|root,COG1188@2|Bacteria,1MZR6@1224|Proteobacteria,1S8VU@1236|Gammaproteobacteria,467YZ@72275|Alteromonadaceae 1236|Gammaproteobacteria J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) hslR GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003727,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009451,GO:0009628,GO:0009987,GO:0016070,GO:0033554,GO:0034605,GO:0034641,GO:0043021,GO:0043023,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - ko:K04762 - - - - ko00000,ko03110 - - - S4 k141_15177_2 1279017.AQYJ01000026_gene340 6.51e-136 389.0 COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,1RMVX@1236|Gammaproteobacteria,4654U@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide uppS GO:0000270,GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006066,GO:0006629,GO:0006720,GO:0006807,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008834,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042546,GO:0043164,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046872,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 ko:K00806 ko00900,ko01110,map00900,map01110 - R06447 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 - - iECBD_1354.ECBD_3445,iECOK1_1307.ECOK1_0175,iECSE_1348.ECSE_0173,iECW_1372.ECW_m0170,iEKO11_1354.EKO11_3744,iEcDH1_1363.EcDH1_3429,iEcE24377_1341.EcE24377A_0178,iEcHS_1320.EcHS_A0176,iNRG857_1313.NRG857_00890,iSFV_1184.SFV_0157,iUMN146_1321.UM146_23675,iUMNK88_1353.UMNK88_178,iWFL_1372.ECW_m0170,iY75_1357.Y75_RS00880 Prenyltransf k141_29602_1 218284.CCDN010000003_gene2989 6.3e-68 229.0 COG1197@1|root,COG1197@2|Bacteria,1TPF1@1239|Firmicutes,4H9NB@91061|Bacilli,1ZBAK@1386|Bacillus 91061|Bacilli L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd - - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF k141_20172_2 1294265.JCM21738_3293 4.57e-19 84.3 COG1385@1|root,COG1385@2|Bacteria,1V1CT@1239|Firmicutes,4HH8P@91061|Bacilli,1ZAV7@1386|Bacillus 91061|Bacilli J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit rsmE GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.193 ko:K09761 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_RNA k141_2109_1 1196323.ALKF01000189_gene1166 2.14e-08 57.8 COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,1TQNH@1239|Firmicutes,4HBB7@91061|Bacilli,26R9W@186822|Paenibacillaceae 91061|Bacilli H Belongs to the precorrin methyltransferase family hemX - 2.1.1.107,4.2.1.75 ko:K02303,ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R03165,R03194 RC00003,RC00871,RC01861 ko00000,ko00001,ko00002,ko01000 - - - HEM4,TP_methylase k141_24901_1 1279017.AQYJ01000019_gene1449 2.06e-134 382.0 COG0088@1|root,COG0088@2|Bacteria,1MXPF@1224|Proteobacteria,1RNNK@1236|Gammaproteobacteria,464IZ@72275|Alteromonadaceae 1236|Gammaproteobacteria J Forms part of the polypeptide exit tunnel rplD GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003700,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008428,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030234,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032069,GO:0032074,GO:0032268,GO:0032269,GO:0032991,GO:0032993,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060698,GO:0060699,GO:0060700,GO:0060701,GO:0060702,GO:0065003,GO:0065007,GO:0065009,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:0098772,GO:0140110,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990904,GO:2000112,GO:2000113,GO:2001141 - ko:K02926 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L4 k141_17604_1 1042377.AFPJ01000052_gene1547 3.79e-87 263.0 COG1210@1|root,COG1210@2|Bacteria,1MV5F@1224|Proteobacteria,1RNDX@1236|Gammaproteobacteria,4650D@72275|Alteromonadaceae 1236|Gammaproteobacteria M UTP-glucose-1-phosphate uridylyltransferase galU - 2.7.7.9 ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 M00129,M00361,M00362,M00549 R00289 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase k141_33064_1 926559.JoomaDRAFT_0959 0.000284 44.3 COG0055@1|root,COG0055@2|Bacteria,4NF1Q@976|Bacteroidetes,1HWM2@117743|Flavobacteriia 976|Bacteroidetes C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits atpD - 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_N k141_33064_2 861299.J421_2628 1.44e-79 249.0 COG0224@1|root,COG0224@2|Bacteria,1ZSZR@142182|Gemmatimonadetes 142182|Gemmatimonadetes C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex atpG - - ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt k141_33064_3 411464.DESPIG_02013 8.12e-67 218.0 COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,42MVX@68525|delta/epsilon subdivisions,2WIK7@28221|Deltaproteobacteria,2M8U7@213115|Desulfovibrionales 28221|Deltaproteobacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit atpA - 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N k141_10566_1 1279017.AQYJ01000028_gene2209 8.53e-225 643.0 COG3008@1|root,COG3008@2|Bacteria,1MU1T@1224|Proteobacteria,1RN89@1236|Gammaproteobacteria,46474@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Paraquat-inducible protein B yebT GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006869,GO:0008150,GO:0009987,GO:0010876,GO:0016020,GO:0016021,GO:0016043,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0033036,GO:0042597,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071840,GO:0071944,GO:0120009 - ko:K06192 - - - - ko00000 - - - MlaD k141_10566_2 1042377.AFPJ01000024_gene765 7.08e-32 118.0 COG2995@1|root,COG2995@2|Bacteria,1MWG1@1224|Proteobacteria,1RM9Z@1236|Gammaproteobacteria,467ES@72275|Alteromonadaceae 1236|Gammaproteobacteria S paraquat-inducible protein A yebS GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0071944 - ko:K03808 - - - - ko00000 - - - PqiA k141_24902_1 318464.IO99_04200 4.59e-83 249.0 COG0454@1|root,COG0456@2|Bacteria,1V6IK@1239|Firmicutes,25CP1@186801|Clostridia,36WYK@31979|Clostridiaceae 186801|Clostridia K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10 k141_21126_1 1116375.VEJY3_20071 1.1e-67 219.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1SYIV@1236|Gammaproteobacteria,1Y2T1@135623|Vibrionales 135623|Vibrionales NT methyl-accepting chemotaxis protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - MCPsignal k141_7974_1 1173028.ANKO01000030_gene3280 1.2e-21 98.2 COG2244@1|root,COG2244@2|Bacteria,1GCMK@1117|Cyanobacteria 1117|Cyanobacteria S Polysaccharide biosynthesis protein - - - - - - - - - - - - Polysacc_synt k141_29604_1 218284.CCDN010000001_gene1026 2.24e-120 350.0 COG0119@1|root,COG0119@2|Bacteria,1TQG3@1239|Firmicutes,4HA1U@91061|Bacilli,1ZC18@1386|Bacillus 91061|Bacilli E Hydroxymethylglutaryl-CoA lyase yngG - 4.1.3.4 ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 M00036,M00088 R01360,R08090 RC00502,RC00503,RC01118,RC01946 ko00000,ko00001,ko00002,ko01000 - - - HMGL-like k141_10567_1 1196031.ALEG01000063_gene3459 1.46e-79 247.0 COG3508@1|root,COG3508@2|Bacteria,1UYZ0@1239|Firmicutes,4HCCC@91061|Bacilli,1ZC6Q@1386|Bacillus 91061|Bacilli Q homogentisate 12-dioxygenase hmgA - 1.13.11.5 ko:K00451 ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120 M00044 R02519 RC00737 ko00000,ko00001,ko00002,ko01000 - - - HgmA k141_15178_1 218284.CCDN010000002_gene2668 3.85e-124 367.0 COG0659@1|root,COG0659@2|Bacteria,1TPI4@1239|Firmicutes,4H9V4@91061|Bacilli,1ZCKC@1386|Bacillus 91061|Bacilli P COG0659 Sulfate permease and related transporters (MFS superfamily) ybaR - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - STAS,Sulfate_transp k141_28185_1 218284.CCDN010000001_gene108 1.22e-94 278.0 COG0669@1|root,COG0669@2|Bacteria,1V3MR@1239|Firmicutes,4HH47@91061|Bacilli,1ZFNZ@1386|Bacillus 91061|Bacilli H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate coaD GO:0003674,GO:0003824,GO:0004595,GO:0006082,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0051186,GO:0051188,GO:0070566,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 ko:K00954 ko00770,ko01100,map00770,map01100 M00120 R03035 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like k141_28185_2 218284.CCDN010000001_gene107 1.22e-75 237.0 COG3314@1|root,COG3314@2|Bacteria,1TR0V@1239|Firmicutes,4HB55@91061|Bacilli,1ZCCT@1386|Bacillus 91061|Bacilli S Sporulation integral membrane protein YlbJ ylbJ - - - - - - - - - - - Gate k141_30510_1 448385.sce4578 1.58e-58 206.0 COG0068@1|root,COG0068@2|Bacteria,1MVP8@1224|Proteobacteria,42M3G@68525|delta/epsilon subdivisions,2WJ51@28221|Deltaproteobacteria,2YTV0@29|Myxococcales 28221|Deltaproteobacteria O Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide hypF - - ko:K04656 - - - - ko00000 - - - Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF k141_17670_1 218284.CCDN010000001_gene1141 2.28e-123 377.0 COG0847@1|root,COG1199@1|root,COG0847@2|Bacteria,COG1199@2|Bacteria,1TQHQ@1239|Firmicutes,4HB2Y@91061|Bacilli,1ZAWI@1386|Bacillus 91061|Bacilli L helicase involved in DNA repair and perhaps also replication dinG - 3.6.4.12 ko:K03722 - - - - ko00000,ko01000,ko03400 - - - DEAD,Helicase_C_2,RNase_T,ResIII k141_28222_1 1166948.JPZL01000001_gene2811 7.04e-14 67.0 2DC3V@1|root,2ZCT0@2|Bacteria,1P99V@1224|Proteobacteria,1SUT0@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_17671_1 218284.CCDN010000001_gene1206 9.31e-104 303.0 COG4698@1|root,COG4698@2|Bacteria,1VF0K@1239|Firmicutes,4HIYN@91061|Bacilli,1ZF26@1386|Bacillus 91061|Bacilli S protein conserved in bacteria ypmS - - - - - - - - - - - DUF2140 k141_31646_2 1453501.JELR01000002_gene860 3.53e-293 803.0 COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,1RP0C@1236|Gammaproteobacteria,465BZ@72275|Alteromonadaceae 1236|Gammaproteobacteria H Aminotransferase class-III - - 2.6.1.18 ko:K00822 ko00280,ko00410,ko00640,ko01100,map00280,map00410,map00640,map01100 - R00907,R04187 RC00008,RC00062,RC00160 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_3 k141_31646_3 1279017.AQYJ01000028_gene2129 1.51e-93 278.0 COG3247@1|root,COG3247@2|Bacteria,1RH69@1224|Proteobacteria,1SAIB@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Short repeat of unknown function (DUF308) - - - - - - - - - - - - DUF308 k141_31646_4 1453501.JELR01000002_gene873 1.98e-215 609.0 COG1167@1|root,COG1167@2|Bacteria,1MVGT@1224|Proteobacteria,1RPFK@1236|Gammaproteobacteria,465V7@72275|Alteromonadaceae 1236|Gammaproteobacteria K helix_turn_helix gluconate operon transcriptional repressor - - - ko:K00375,ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 - R01939 RC00006 ko00000,ko00001,ko01000,ko03000 - - - Aminotran_1_2,GntR k141_3382_1 1279017.AQYJ01000025_gene609 3.49e-19 87.4 COG2355@1|root,COG2355@2|Bacteria,1MWEW@1224|Proteobacteria,1RYET@1236|Gammaproteobacteria,469YE@72275|Alteromonadaceae 1236|Gammaproteobacteria E Membrane dipeptidase (Peptidase family M19) - - - - - - - - - - - - Peptidase_M19 k141_3382_2 1453501.JELR01000001_gene2113 9.77e-59 186.0 COG5608@1|root,COG5608@2|Bacteria,1MZF0@1224|Proteobacteria,1SEGD@1236|Gammaproteobacteria,468MK@72275|Alteromonadaceae 1236|Gammaproteobacteria S Late embryogenesis abundant protein - - - - - - - - - - - - LEA_2 k141_3382_4 1453501.JELR01000001_gene2111 9.13e-110 318.0 COG1595@1|root,COG1595@2|Bacteria,1RD9G@1224|Proteobacteria,1S82R@1236|Gammaproteobacteria,4681R@72275|Alteromonadaceae 1236|Gammaproteobacteria K Sigma-70, region 4 algT - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_3382_5 1453501.JELR01000001_gene2110 1.17e-59 195.0 2EIJE@1|root,33CAQ@2|Bacteria,1NH29@1224|Proteobacteria,1SGJY@1236|Gammaproteobacteria,46969@72275|Alteromonadaceae 1236|Gammaproteobacteria S Psort location CytoplasmicMembrane, score - - - - - - - - - - - - - k141_16511_1 218284.CCDN010000001_gene169 6.65e-88 283.0 COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria,1TQXZ@1239|Firmicutes,4HB0B@91061|Bacilli,1ZDEG@1386|Bacillus 91061|Bacilli S von Willebrand factor type A domain - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - GATase1_like,VWA,VWA_2,VWA_3 k141_4597_1 218284.CCDN010000001_gene1427 1.21e-73 231.0 COG2340@1|root,COG2340@2|Bacteria,1TSUX@1239|Firmicutes,4HDMJ@91061|Bacilli,1ZB45@1386|Bacillus 91061|Bacilli G protein with SCP PR1 domains - - - - - - - - - - - - CAP,CAP_assoc_N,SLH k141_15211_1 1294265.JCM21738_3230 4.3e-92 272.0 2ADZG@1|root,313RY@2|Bacteria,1V6JT@1239|Firmicutes,4HH5B@91061|Bacilli,1ZCER@1386|Bacillus 91061|Bacilli S Sporulation protein YyaC yyaC - - - - - - - - - - - DUF1256 k141_30512_1 218284.CCDN010000006_gene3610 1.25e-104 306.0 COG1647@1|root,COG1647@2|Bacteria,1TQ7X@1239|Firmicutes,4HBE6@91061|Bacilli,1ZAVD@1386|Bacillus 91061|Bacilli S Carboxylesterase est GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0008150,GO:0008152,GO:0016020,GO:0016298,GO:0016787,GO:0016788,GO:0044238,GO:0071704 3.1.1.1 ko:K03928 - - - - ko00000,ko01000 - - - Hydrolase_4 k141_21178_1 1279017.AQYJ01000028_gene2321 2.57e-83 295.0 COG2982@1|root,COG2982@2|Bacteria,1MUME@1224|Proteobacteria,1RNPC@1236|Gammaproteobacteria,464KK@72275|Alteromonadaceae 1236|Gammaproteobacteria M Domain of Unknown Function (DUF748) - - - - - - - - - - - - DUF748,OmpA k141_33108_1 55601.VANGNB10_cII0337c 5.23e-279 777.0 COG0270@1|root,COG0270@2|Bacteria,1MV9H@1224|Proteobacteria,1RPM4@1236|Gammaproteobacteria,1XXF4@135623|Vibrionales 135623|Vibrionales H C-5 cytosine-specific DNA methylase - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k141_33108_2 55601.VANGNB10_cII0338c 1.58e-38 140.0 28JKN@1|root,2Z9DE@2|Bacteria,1N4VH@1224|Proteobacteria,1SA4H@1236|Gammaproteobacteria 1236|Gammaproteobacteria S MvaI/BcnI restriction endonuclease family - - - - - - - - - - - - MvaI_BcnI k141_4598_1 218284.CCDN010000002_gene2156 1.06e-121 379.0 COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,4HAFP@91061|Bacilli,1ZBJ3@1386|Bacillus 91061|Bacilli V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family swrC - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran k141_15212_1 1453501.JELR01000002_gene342 1.53e-84 278.0 COG1361@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4932@2|Bacteria,1R5G4@1224|Proteobacteria,1SEWA@1236|Gammaproteobacteria,469S7@72275|Alteromonadaceae 1236|Gammaproteobacteria M Domain of unknown function DUF11 - - - - - - - - - - - - DUF11,SdrD_B k141_37789_1 1116375.VEJY3_18341 3.54e-181 507.0 COG0583@1|root,COG0583@2|Bacteria,1NUAB@1224|Proteobacteria,1RNYQ@1236|Gammaproteobacteria,1XSF5@135623|Vibrionales 1236|Gammaproteobacteria K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_37789_2 1116375.VEJY3_18336 1.62e-143 409.0 COG0639@1|root,COG0639@2|Bacteria,1N106@1224|Proteobacteria,1S9QJ@1236|Gammaproteobacteria,1XZ20@135623|Vibrionales 135623|Vibrionales T Calcineurin-like phosphoesterase - - 3.1.3.16 ko:K07313 - - - - ko00000,ko01000 - - - Metallophos k141_37789_3 1116375.VEJY3_18331 9.3e-126 359.0 COG3911@1|root,COG3911@2|Bacteria,1RBSG@1224|Proteobacteria,1S31D@1236|Gammaproteobacteria,1XZZB@135623|Vibrionales 135623|Vibrionales S AAA domain - - - - - - - - - - - - AAA_28 k141_37789_4 1116375.VEJY3_18326 1.27e-97 288.0 COG2078@1|root,COG2078@2|Bacteria,1RJP4@1224|Proteobacteria,1SBD9@1236|Gammaproteobacteria,1XX6I@135623|Vibrionales 135623|Vibrionales S AMMECR1 - - - ko:K09141 - - - - ko00000 - - - AMMECR1 k141_37789_5 1116375.VEJY3_18321 1.05e-165 466.0 COG1355@1|root,COG1355@2|Bacteria,1MXK5@1224|Proteobacteria,1RQPK@1236|Gammaproteobacteria,1XX60@135623|Vibrionales 135623|Vibrionales S Memo-like protein - - - ko:K06990 - - - - ko00000,ko04812 - - - Memo k141_37789_6 323850.Shew_0932 2.29e-235 650.0 COG1180@1|root,COG1180@2|Bacteria,1R8XY@1224|Proteobacteria,1THAY@1236|Gammaproteobacteria,2QB3G@267890|Shewanellaceae 1236|Gammaproteobacteria C PFAM Radical SAM domain protein - - 1.97.1.4 ko:K04069 - - R04710 - ko00000,ko01000 - - - Radical_SAM k141_37789_7 377629.TERTU_2556 9.89e-07 57.4 COG0810@1|root,COG0810@2|Bacteria,1MZXC@1224|Proteobacteria,1S81P@1236|Gammaproteobacteria,2PQ9A@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria M TonB C terminal tonB - - ko:K03832 - - - - ko00000,ko02000 2.C.1.1 - - TonB_C k141_37789_8 1348635.BBJY01000002_gene3661 6.41e-12 66.2 COG0848@1|root,COG0848@2|Bacteria,1N85T@1224|Proteobacteria,1SE81@1236|Gammaproteobacteria,1Y2AY@135623|Vibrionales 135623|Vibrionales U Biopolymer transport protein ExbD/TolR - - - - - - - - - - - - ExbD k141_37789_9 1280949.HAD_17221 1.7e-38 139.0 COG0811@1|root,COG0811@2|Bacteria,1RDX3@1224|Proteobacteria,2TQY6@28211|Alphaproteobacteria 28211|Alphaproteobacteria U MotA/TolQ/ExbB proton channel family - - - ko:K03561 - - - - ko00000,ko02000 1.A.30.2.1 - - MotA_ExbB k141_37789_10 666509.RCA23_c07530 1.93e-09 58.5 COG1133@1|root,COG1133@2|Bacteria,1QU39@1224|Proteobacteria,2TVXG@28211|Alphaproteobacteria 28211|Alphaproteobacteria I ABC-type long-chain fatty acid transport system fused permease and ATPase bacA GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006855,GO:0008150,GO:0015238,GO:0015291,GO:0015638,GO:0015833,GO:0015893,GO:0016020,GO:0016021,GO:0019534,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0042221,GO:0042493,GO:0042884,GO:0042885,GO:0042886,GO:0042887,GO:0042891,GO:0042895,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:1901998,GO:1904680 - ko:K17938 - - - - ko00000,ko02000 9.A.18.1 - - SbmA_BacA k141_17673_1 1279017.AQYJ01000023_gene3274 4.43e-78 250.0 COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,1RP55@1236|Gammaproteobacteria,465RX@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1178 ABC-type Fe3 transport system, permease component - - - ko:K02011 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - BPD_transp_1 k141_37790_2 292564.Cyagr_0210 2.84e-05 46.6 COG0454@1|root,COG0456@2|Bacteria,1G5TG@1117|Cyanobacteria,22T1E@167375|Cyanobium 1117|Cyanobacteria K FR47-like protein rimI - 2.3.1.128 ko:K03789 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_1,Acetyltransf_10 k141_21180_1 218284.CCDN010000004_gene3133 3.72e-100 306.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,1ZBXB@1386|Bacillus 91061|Bacilli V COG1132 ABC-type multidrug transport system, ATPase and permease components yheI - - ko:K18216,ko:K18889 ko02010,map02010 M00635,M00707 - - ko00000,ko00001,ko00002,ko01504,ko02000 3.A.1,3.A.1.106.13,3.A.1.106.5 - - ABC_membrane,ABC_tran k141_31648_1 1042377.AFPJ01000037_gene2979 2.71e-103 303.0 COG0655@1|root,COG0655@2|Bacteria,1MW7N@1224|Proteobacteria,1S23B@1236|Gammaproteobacteria,466IM@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the WrbA family wrbA - 1.6.5.2 ko:K03809 ko00130,ko01110,map00130,map01110 - R02964,R03643,R03816 RC00819 ko00000,ko00001,ko01000 - - - FMN_red k141_31648_2 1279017.AQYJ01000021_gene2908 2.2e-52 167.0 COG3308@1|root,COG3308@2|Bacteria,1N5UB@1224|Proteobacteria,1SAAJ@1236|Gammaproteobacteria,4693B@72275|Alteromonadaceae 1236|Gammaproteobacteria S Predicted membrane protein (DUF2069) - - - - - - - - - - - - DUF2069 k141_33109_1 1279017.AQYJ01000024_gene1104 6.12e-194 567.0 COG0587@1|root,COG0587@2|Bacteria,1MUE4@1224|Proteobacteria,1RQA8@1236|Gammaproteobacteria,464B5@72275|Alteromonadaceae 1236|Gammaproteobacteria L DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase dnaE2 GO:0003674,GO:0003824,GO:0003887,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K14162 - - - - ko00000,ko01000,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon k141_21181_1 455436.DS989811_gene1849 1.28e-76 239.0 COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,465WS@72275|Alteromonadaceae 1236|Gammaproteobacteria E Gamma-glutamyltranspeptidase ggt_2 - 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept k141_34362_2 1453501.JELR01000001_gene2066 2.45e-68 209.0 COG0290@1|root,COG0290@2|Bacteria,1RDD2@1224|Proteobacteria,1S4E6@1236|Gammaproteobacteria,466GC@72275|Alteromonadaceae 1236|Gammaproteobacteria J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins infC GO:0000049,GO:0001731,GO:0002181,GO:0002183,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016020,GO:0016043,GO:0019222,GO:0019538,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032268,GO:0032270,GO:0032790,GO:0032984,GO:0032988,GO:0032991,GO:0034248,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043254,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045727,GO:0045948,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065003,GO:0065007,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:1901193,GO:1901195,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:1904688,GO:1904690,GO:1990856,GO:1990904,GO:2000112,GO:2000765,GO:2000767 - ko:K02520 - - - - ko00000,ko03012,ko03029 - - - IF3_C,IF3_N k141_34362_3 1453501.JELR01000001_gene2065 0.0 1199.0 COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,1RMYE@1236|Gammaproteobacteria,464IQ@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) thrS GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD k141_34362_4 1042377.AFPJ01000019_gene2489 0.0 1184.0 COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,1RN6Z@1236|Gammaproteobacteria,4645B@72275|Alteromonadaceae 1236|Gammaproteobacteria L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage uvrB GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009314,GO:0009380,GO:0009628,GO:0032991,GO:0042802,GO:0044424,GO:0044464,GO:0050896,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - ko:K03702 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - Helicase_C,ResIII,UVR,UvrB k141_16513_1 223926.28807654 1.32e-32 123.0 COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,1RNM1@1236|Gammaproteobacteria,1XT1U@135623|Vibrionales 135623|Vibrionales E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides pepA - 3.4.11.1 ko:K01255 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - Peptidase_M17,Peptidase_M17_N k141_16513_2 1116375.VEJY3_13575 1.31e-101 294.0 COG2927@1|root,COG2927@2|Bacteria,1MZ3V@1224|Proteobacteria,1S697@1236|Gammaproteobacteria,1XX1X@135623|Vibrionales 135623|Vibrionales L DNA polymerase III chi subunit holC - 2.7.7.7 ko:K02339 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_chi k141_16513_3 674977.VMC_18690 2.66e-99 312.0 COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,1RNEB@1236|Gammaproteobacteria,1XTVJ@135623|Vibrionales 135623|Vibrionales J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner valS GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 k141_15214_1 1294265.JCM21738_2904 1.38e-130 381.0 COG0114@1|root,COG0114@2|Bacteria,1UHPH@1239|Firmicutes,4HA6P@91061|Bacilli,1ZS23@1386|Bacillus 91061|Bacilli C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate fumC GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 M00009,M00011,M00173,M00376 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS09430 FumaraseC_C,Lyase_1 k141_3385_1 218284.CCDN010000012_gene4438 1.67e-161 462.0 COG0172@1|root,COG0172@2|Bacteria,1TP4W@1239|Firmicutes,4H9Y4@91061|Bacilli,1ZCBQ@1386|Bacillus 91061|Bacilli J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) serS - 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Seryl_tRNA_N,tRNA-synt_2b k141_17676_1 1196031.ALEG01000047_gene140 1.24e-129 380.0 COG3314@1|root,COG3314@2|Bacteria,1TR35@1239|Firmicutes,4HAB6@91061|Bacilli,1ZARZ@1386|Bacillus 91061|Bacilli S protein conserved in bacteria - - - - - - - - - - - - Gate k141_27441_1 218284.CCDN010000001_gene179 4.68e-153 434.0 COG0583@1|root,COG0583@2|Bacteria,1TZ6U@1239|Firmicutes,4HB3Y@91061|Bacilli,1ZB8N@1386|Bacillus 91061|Bacilli K Transcriptional regulator ccpC - - - - - - - - - - - HTH_1,LysR_substrate k141_26321_1 260799.BAS2067 4.37e-64 202.0 COG1794@1|root,COG1794@2|Bacteria,1TR3U@1239|Firmicutes,4HCAN@91061|Bacilli,1ZDW9@1386|Bacillus 91061|Bacilli M Belongs to the aspartate glutamate racemases family racD - 5.1.1.13 ko:K01779 ko00250,ko01054,map00250,map01054 - R00491 RC00302 ko00000,ko00001,ko01000 - - - Asp_Glu_race k141_28705_1 218284.CCDN010000006_gene3677 3.08e-107 312.0 COG0500@1|root,COG2226@2|Bacteria,1VAEA@1239|Firmicutes,4HGJC@91061|Bacilli,1ZQ1S@1386|Bacillus 91061|Bacilli Q rRNA small subunit methyltransferase G - - - - - - - - - - - - Methyltransf_11,Methyltransf_25 k141_34619_1 1121380.JNIW01000006_gene461 8.18e-15 80.1 COG0305@1|root,COG1372@1|root,COG0305@2|Bacteria,COG1372@2|Bacteria,1WIM7@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus L Participates in initiation and elongation during chromosome replication dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C,Intein_splicing,LAGLIDADG_3 k141_34619_3 1462526.BN990_01821 3.05e-97 293.0 COG3935@1|root,COG3935@2|Bacteria,1V9YA@1239|Firmicutes,4HN3B@91061|Bacilli 91061|Bacilli L primosome component and related proteins - - - - - - - - - - - - DnaB_2 k141_34619_4 1246484.D479_07167 4.47e-18 78.6 COG2002@1|root,COG2002@2|Bacteria,1W1P8@1239|Firmicutes 1239|Firmicutes K SpoVT / AbrB like domain - - - - - - - - - - - - - k141_31075_1 218284.CCDN010000002_gene2184 8.25e-177 503.0 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli,1ZAXK@1386|Bacillus 91061|Bacilli C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively aldA - 1.2.1.21,1.2.1.22 ko:K07248 ko00620,ko00630,ko01120,map00620,map00630,map01120 - R00203,R01333,R01446 RC00080,RC00104,RC00242 ko00000,ko00001,ko01000 - - - Aldedh k141_14429_1 218284.CCDN010000002_gene2301 1.2e-114 336.0 COG1957@1|root,COG1957@2|Bacteria,1TSAR@1239|Firmicutes,4HDCS@91061|Bacilli,1ZD4R@1386|Bacillus 91061|Bacilli F nucleoside hydrolase - - 3.2.2.1 ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 - R01245,R01273,R01677,R01770,R02143 RC00033,RC00063,RC00122,RC00318,RC00485 ko00000,ko00001,ko01000 - - - IU_nuc_hydro k141_3728_1 1285586.H131_20332 1.58e-40 137.0 2ERT6@1|root,33JCD@2|Bacteria,1VNGD@1239|Firmicutes,4HRHI@91061|Bacilli,3IYR7@400634|Lysinibacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_29833_1 1116375.VEJY3_17206 2.89e-164 469.0 COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,1RNW9@1236|Gammaproteobacteria,1XUZX@135623|Vibrionales 135623|Vibrionales E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - 2.6.1.76 ko:K15785 ko00260,map00260 - R06977 RC00006,RC00062 ko00000,ko00001,ko01000 - - - Aminotran_3 k141_2533_1 1453501.JELR01000001_gene2827 1.16e-75 241.0 COG1538@1|root,COG1538@2|Bacteria,1MYX2@1224|Proteobacteria,1RYIR@1236|Gammaproteobacteria,46CEK@72275|Alteromonadaceae 1236|Gammaproteobacteria MU Outer membrane efflux protein - - - ko:K12543 - M00330 - - ko00000,ko00002,ko02000,ko02044 1.B.17,3.A.1.109.4 - - OEP k141_191_1 218284.CCDN010000007_gene3810 3.45e-55 193.0 COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,4H9RZ@91061|Bacilli,1ZBEA@1386|Bacillus 91061|Bacilli NT chemotaxis protein mcpC GO:0005575,GO:0005623,GO:0005886,GO:0006935,GO:0008150,GO:0009605,GO:0016020,GO:0040011,GO:0042221,GO:0042330,GO:0044464,GO:0050896,GO:0050918,GO:0071944 - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal,dCache_1 k141_16769_1 316274.Haur_0949 1.55e-65 221.0 COG1132@1|root,COG1132@2|Bacteria,2G63W@200795|Chloroflexi,376YV@32061|Chloroflexia 32061|Chloroflexia P ABC transporter transmembrane region - - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran k141_12027_8 1116375.VEJY3_06915 2.79e-100 291.0 COG0784@1|root,COG0784@2|Bacteria,1MYIP@1224|Proteobacteria,1S89X@1236|Gammaproteobacteria,1XWVH@135623|Vibrionales 135623|Vibrionales T Chemotaxis protein cheY - - - ko:K03413 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - Response_reg k141_12027_9 1116375.VEJY3_06910 2.13e-282 776.0 COG0664@1|root,COG4191@1|root,COG0664@2|Bacteria,COG4191@2|Bacteria,1NFPA@1224|Proteobacteria,1SYIF@1236|Gammaproteobacteria,1XUT2@135623|Vibrionales 135623|Vibrionales T Histidine kinase - - - - - - - - - - - - HATPase_c,cNMP_binding k141_12027_10 223926.28806362 1.7e-284 783.0 COG0471@1|root,COG0471@2|Bacteria,1R6QF@1224|Proteobacteria,1RQIG@1236|Gammaproteobacteria,1XTZX@135623|Vibrionales 135623|Vibrionales P COG0471 Di- and tricarboxylate transporters - - - ko:K14445 - - - - ko00000,ko02000 2.A.47.1 - - Na_sulph_symp k141_1291_1 218284.CCDN010000007_gene3887 1.66e-117 349.0 COG1502@1|root,COG1502@2|Bacteria,1TQ2Q@1239|Firmicutes,4H9SX@91061|Bacilli,1ZBA2@1386|Bacillus 91061|Bacilli I PLD-like domain cls2 - - - - - - - - - - - PLDc_2 k141_27459_1 1279017.AQYJ01000025_gene648 1.06e-84 262.0 COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,1RMP9@1236|Gammaproteobacteria,4649Y@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG4591 ABC-type transport system, involved in lipoprotein release, permease component lolC - - ko:K09808 ko02010,map02010 M00255 - - ko00000,ko00001,ko00002,ko02000 3.A.1.125 - - FtsX,MacB_PCD k141_27459_2 1042377.AFPJ01000007_gene1891 1.21e-135 389.0 COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,1RMWK@1236|Gammaproteobacteria,466E9@72275|Alteromonadaceae 1236|Gammaproteobacteria V Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner lolD GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0015399,GO:0015405,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051234,GO:0051641,GO:0055085,GO:0070727,GO:0071944,GO:0072657,GO:0089705,GO:0097159,GO:0097367,GO:0098796,GO:0098797,GO:1901265,GO:1901363,GO:1990778 - ko:K09810 ko02010,map02010 M00255 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.125 - - ABC_tran k141_27459_3 1279017.AQYJ01000025_gene650 4.17e-243 674.0 COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,1RMP9@1236|Gammaproteobacteria,4649Y@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG4591 ABC-type transport system, involved in lipoprotein release, permease component lolC - - ko:K09808 ko02010,map02010 M00255 - - ko00000,ko00001,ko00002,ko02000 3.A.1.125 - - FtsX,MacB_PCD k141_2556_3 1116375.VEJY3_17196 0.0 1178.0 COG2987@1|root,COG2987@2|Bacteria,1MU4W@1224|Proteobacteria,1RP89@1236|Gammaproteobacteria,1XTBK@135623|Vibrionales 135623|Vibrionales H Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate hutU GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016153,GO:0016829,GO:0016835,GO:0016836,GO:0019439,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0052803,GO:0052805,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 4.2.1.49 ko:K01712 ko00340,ko01100,map00340,map01100 M00045 R02914 RC00804 ko00000,ko00001,ko00002,ko01000 - - - Urocanase,Urocanase_C,Urocanase_N k141_6155_1 1260251.SPISAL_06950 3.39e-11 61.6 COG3113@1|root,COG3113@2|Bacteria 2|Bacteria S response to antibiotic - - - ko:K07122 ko02010,map02010 M00210 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27.3 - - STAS_2 k141_6155_2 160492.XF_0418 1.41e-11 64.7 COG2854@1|root,COG2854@2|Bacteria,1N022@1224|Proteobacteria,1TA6U@1236|Gammaproteobacteria,1X35G@135614|Xanthomonadales 135614|Xanthomonadales Q toluene tolerance yrbC - - ko:K07323 ko02010,map02010 M00210 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27.3 - - MlaC k141_16794_1 1279017.AQYJ01000027_gene1783 6.68e-67 227.0 COG1404@1|root,COG1404@2|Bacteria,1MVJE@1224|Proteobacteria,1RQ2M@1236|Gammaproteobacteria,4683H@72275|Alteromonadaceae 1236|Gammaproteobacteria O Peptidase inhibitor I9 - - - - - - - - - - - - Inhibitor_I9,PA,Peptidase_S8 k141_2557_1 218284.CCDN010000007_gene3905 9.91e-126 367.0 COG0156@1|root,COG0156@2|Bacteria,1TPUX@1239|Firmicutes,4HAH3@91061|Bacilli,1ZAUZ@1386|Bacillus 91061|Bacilli H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide kbl GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29 ko:K00639 ko00260,map00260 - R00371 RC00004,RC00394 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 k141_3754_1 1306990.BARG01000024_gene2703 1.7e-16 84.0 COG1052@1|root,COG1052@2|Bacteria,2I869@201174|Actinobacteria 201174|Actinobacteria CH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - - - - - - - - - - 2-Hacid_dh,2-Hacid_dh_C k141_8506_1 796606.BMMGA3_10650 4.94e-99 294.0 COG0289@1|root,COG0289@2|Bacteria,1TR9D@1239|Firmicutes,4HA5X@91061|Bacilli,1ZAWD@1386|Bacillus 91061|Bacilli E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate dapB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R04198,R04199 RC00478 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU22490 DapB_C,DapB_N k141_7285_1 218284.CCDN010000005_gene3291 3.16e-185 530.0 COG1164@1|root,COG1164@2|Bacteria,1TP4P@1239|Firmicutes,4HA7X@91061|Bacilli,1ZCHA@1386|Bacillus 91061|Bacilli E oligoendopeptidase F pepF GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - ko:K08602 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M3,Peptidase_M3_N k141_34642_1 390989.JOEG01000034_gene1647 0.000346 48.5 COG2199@1|root,COG3850@1|root,COG3706@2|Bacteria,COG3850@2|Bacteria,2IA4H@201174|Actinobacteria,4D9U5@85008|Micromonosporales 201174|Actinobacteria T Diguanylate cyclase - - - - - - - - - - - - GAF,GAF_2,GGDEF,HAMP k141_13261_2 315750.BPUM_3399 9.5e-61 198.0 COG0457@1|root,COG0457@2|Bacteria,1V3U6@1239|Firmicutes,4HFWW@91061|Bacilli,1ZHAD@1386|Bacillus 91061|Bacilli S Tetratrico peptide repeat - - - - - - - - - - - - TPR_5,TPR_6,TPR_8 k141_15646_1 997296.PB1_13849 6.5e-110 319.0 COG0177@1|root,COG0177@2|Bacteria,1TRAK@1239|Firmicutes,4HATD@91061|Bacilli,1ZBJE@1386|Bacillus 91061|Bacilli L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate nth - 4.2.99.18 ko:K10773 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD k141_220_1 1385514.N782_12480 1.08e-76 255.0 COG0454@1|root,COG0456@2|Bacteria,1TQQA@1239|Firmicutes,4HBXN@91061|Bacilli,2YBGI@289201|Pontibacillus 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10 k141_20319_1 665959.HMPREF1013_02808 6.57e-27 109.0 COG1804@1|root,COG1804@2|Bacteria,1TP54@1239|Firmicutes,4HC4S@91061|Bacilli,1ZQZX@1386|Bacillus 91061|Bacilli C acyl-CoA transferases carnitine dehydratase - - - - - - - - - - - - CoA_transf_3 k141_20319_2 218284.CCDN010000002_gene2298 2.58e-64 197.0 COG3324@1|root,COG3324@2|Bacteria,1V48C@1239|Firmicutes,4HHTZ@91061|Bacilli,1ZFPT@1386|Bacillus 91061|Bacilli S enzyme related to lactoylglutathione lyase - - - ko:K06996 - - - - ko00000 - - - Glyoxalase k141_22746_1 218284.CCDN010000007_gene3940 5.04e-113 335.0 COG1078@1|root,COG1078@2|Bacteria,1TPVB@1239|Firmicutes,4HAX8@91061|Bacilli,1ZBRB@1386|Bacillus 91061|Bacilli S COG1078 HD superfamily phosphohydrolases ywfO GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 - ko:K06885 - - - - ko00000 - - - HD k141_9645_1 1280001.BAOA01000123_gene1037 2.48e-34 127.0 COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,1RNN1@1236|Gammaproteobacteria,1XWDE@135623|Vibrionales 135623|Vibrionales S AI-2E family transporter - - - - - - - - - - - - AI-2E_transport k141_16795_1 1211814.CAPG01000024_gene862 4.39e-69 226.0 COG0640@1|root,COG0640@2|Bacteria,1V5AM@1239|Firmicutes,4IDGZ@91061|Bacilli,1ZFWA@1386|Bacillus 91061|Bacilli K helix_turn_helix, Arsenical Resistance Operon Repressor - - - - - - - - - - - - HTH_5 k141_29853_2 218284.CCDN010000001_gene590 1.19e-104 313.0 COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,4H9Q8@91061|Bacilli,1ZBRE@1386|Bacillus 91061|Bacilli D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase tig GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K03545 - - - - ko00000 - - - FKBP_C,Trigger_C,Trigger_N k141_4903_1 218284.CCDN010000001_gene1281 1.37e-109 327.0 COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,4HB31@91061|Bacilli,1ZARE@1386|Bacillus 91061|Bacilli EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia trpE GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.1.3.27 ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Anth_synt_I_N,Chorismate_bind k141_12029_1 315730.BcerKBAB4_1939 8.72e-91 279.0 COG0639@1|root,COG0639@2|Bacteria,1UYWX@1239|Firmicutes,4HEJF@91061|Bacilli,1ZFAS@1386|Bacillus 91061|Bacilli T Calcineurin-like phosphoesterase - - 3.1.3.16 ko:K01090 - - - - ko00000,ko01000 - - - Metallophos k141_25079_1 1279017.AQYJ01000029_gene3686 4.56e-214 603.0 COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,1RNV5@1236|Gammaproteobacteria,46672@72275|Alteromonadaceae 1236|Gammaproteobacteria I Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) atuC - 6.4.1.5 ko:K13778 ko00281,map00281 - R03494 RC00367,RC00942 ko00000,ko00001,ko01000 - - - Carboxyl_trans k141_25079_2 1279017.AQYJ01000029_gene3687 1.08e-166 471.0 COG1028@1|root,COG1028@2|Bacteria,1PFUB@1224|Proteobacteria,1RS3G@1236|Gammaproteobacteria,466BV@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) atuB - - ko:K13774 ko00281,map00281 - R08087,R08096,R10125,R10126 RC00080,RC00087 ko00000,ko00001 - - - adh_short_C2 k141_32200_2 1116375.VEJY3_23421 1.34e-183 510.0 COG0437@1|root,COG0437@2|Bacteria,1N9WY@1224|Proteobacteria,1RNHT@1236|Gammaproteobacteria,1XUAQ@135623|Vibrionales 135623|Vibrionales C Quinol dehydrogenase napG - - ko:K02573 - - - - ko00000 - - - Fer4_4,Fer4_7 k141_32200_3 1116375.VEJY3_23426 1.78e-105 305.0 COG1247@1|root,COG1247@2|Bacteria,1QUGY@1224|Proteobacteria,1T1YJ@1236|Gammaproteobacteria,1XVDF@135623|Vibrionales 135623|Vibrionales M COG0454 Histone acetyltransferase HPA2 and related acetyltransferases yhhY - - ko:K03825 - - - - ko00000,ko01000 - - - Acetyltransf_1 k141_32200_4 1116375.VEJY3_23431 2.56e-186 522.0 COG2334@1|root,COG2334@2|Bacteria,1R7E4@1224|Proteobacteria,1RRTW@1236|Gammaproteobacteria,1XVKF@135623|Vibrionales 135623|Vibrionales S Ecdysteroid kinase VPA1488 - - - - - - - - - - - EcKinase k141_32200_5 1116375.VEJY3_23436 1.32e-51 163.0 COG2388@1|root,COG2388@2|Bacteria,1NH9Z@1224|Proteobacteria,1SBPA@1236|Gammaproteobacteria,1XZ3G@135623|Vibrionales 135623|Vibrionales S GCN5-related N-acetyl-transferase - - - ko:K06975 - - - - ko00000 - - - Acetyltransf_CG k141_32200_6 223926.28809893 2.9e-123 356.0 2CA3C@1|root,3336E@2|Bacteria,1NH8Y@1224|Proteobacteria,1SI0F@1236|Gammaproteobacteria,1Y33P@135623|Vibrionales 135623|Vibrionales S Flagellar protein YcgR - - - - - - - - - - - - PilZ,YcgR_2 k141_2558_1 1131730.BAVI_03814 7.77e-40 144.0 COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TSKR@1239|Firmicutes,4H9R5@91061|Bacilli,1ZDUE@1386|Bacillus 91061|Bacilli T COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain - - - ko:K07720 ko02020,map02020 M00519 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_18,HTH_AraC,Response_reg k141_2558_2 1131730.BAVI_03819 1.95e-19 88.2 COG2972@1|root,COG2972@2|Bacteria,1TSF9@1239|Firmicutes,4HAIW@91061|Bacilli,1ZC6Y@1386|Bacillus 91061|Bacilli T Histidine kinase - - - - - - - - - - - - HAMP,HATPase_c,His_kinase k141_221_1 218284.CCDN010000007_gene3932 1.41e-70 214.0 COG2363@1|root,COG2363@2|Bacteria,1VA79@1239|Firmicutes,4HKHG@91061|Bacilli,1ZGYJ@1386|Bacillus 91061|Bacilli S small membrane protein ywdK - - - - - - - - - - - DUF423 k141_19148_1 1237149.C900_00448 6.53e-63 206.0 COG2116@1|root,COG2116@2|Bacteria,4NFNU@976|Bacteroidetes,47Q8C@768503|Cytophagia 976|Bacteroidetes P Formate/nitrite transporter - - - ko:K21990,ko:K21993 - - - - ko00000,ko02000 1.A.16.2,1.A.16.4 - - Form_Nir_trans k141_19148_2 236097.ADG881_3173 9.89e-105 314.0 COG3965@1|root,COG3965@2|Bacteria,1MXVG@1224|Proteobacteria,1RSB7@1236|Gammaproteobacteria,1XPNA@135619|Oceanospirillales 135619|Oceanospirillales P Cation efflux family - - - - - - - - - - - - Cation_efflux k141_34643_1 1121938.AUDY01000012_gene3774 1.12e-37 137.0 COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli,3NEFQ@45667|Halobacillus 91061|Bacilli G phosphotransferase system, EIIB sacP GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563 2.7.1.211 ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 M00269 R00811 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.1,4.A.1.2.10,4.A.1.2.12,4.A.1.2.9 - iYO844.BSU38050 PTS_EIIB,PTS_EIIC k141_13262_1 1453501.JELR01000001_gene2380 5.26e-69 218.0 COG4795@1|root,COG4795@2|Bacteria,1RJAE@1224|Proteobacteria,1S5ZZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria U General secretion pathway protein J gspJ GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0098776 - ko:K02459 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - N_methyl,T2SSJ k141_6159_1 218284.CCDN010000001_gene1438 2.53e-50 160.0 2E4AM@1|root,32XKC@2|Bacteria,1VE9E@1239|Firmicutes,4HN07@91061|Bacilli,1ZJ0J@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_31099_1 1280001.BAOA01000035_gene2443 4.44e-32 112.0 2AWMA@1|root,31NI1@2|Bacteria,1QK8S@1224|Proteobacteria,1TIC8@1236|Gammaproteobacteria,1XYUV@135623|Vibrionales 135623|Vibrionales S Phage shock protein G (Phageshock_PspG) pspG - - - - - - - - - - - Phageshock_PspG k141_31099_2 223926.28807737 3.09e-228 629.0 COG0042@1|root,COG0042@2|Bacteria,1MUY1@1224|Proteobacteria,1RN28@1236|Gammaproteobacteria,1XUYB@135623|Vibrionales 135623|Vibrionales J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs dusA - - ko:K05539 - - - - ko00000,ko01000,ko03016 - - - Dus k141_31099_3 1219076.N646_1824 8.72e-98 285.0 COG0735@1|root,COG0735@2|Bacteria,1MZIW@1224|Proteobacteria,1S5ZI@1236|Gammaproteobacteria,1XWW0@135623|Vibrionales 135623|Vibrionales K Belongs to the Fur family zur - - ko:K09823 ko02024,map02024 - - - ko00000,ko00001,ko03000 - - - FUR k141_31099_4 1219076.N646_1825 1.11e-104 302.0 COG1406@1|root,COG1406@2|Bacteria,1RATZ@1224|Proteobacteria,1S22M@1236|Gammaproteobacteria,1XTSB@135623|Vibrionales 135623|Vibrionales N inhibitor of MCP methylation, homolog of CheC cheX - - ko:K03409 ko02030,map02030 - - - ko00000,ko00001,ko02035 - - - CheX k141_31099_5 1116375.VEJY3_13980 0.0 1079.0 COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,1RNIT@1236|Gammaproteobacteria,1XT97@135623|Vibrionales 135623|Vibrionales G Belongs to the GPI family pgi GO:0003674,GO:0003824,GO:0004347,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGI k141_31099_6 1280001.BAOA01000035_gene2438 1.45e-91 268.0 COG0432@1|root,COG0432@2|Bacteria,1RH13@1224|Proteobacteria,1S3VP@1236|Gammaproteobacteria,1XWZM@135623|Vibrionales 135623|Vibrionales S Uncharacterised protein family UPF0047 - - - - - - - - - - - - UPF0047 k141_31099_7 223926.28807743 7.7e-244 674.0 COG4775@1|root,COG4775@2|Bacteria,1R8JJ@1224|Proteobacteria,1RQCW@1236|Gammaproteobacteria,1XSKA@135623|Vibrionales 135623|Vibrionales M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane VP2733 - - - - - - - - - - - Bac_surface_Ag k141_31099_8 1219076.N646_1828 2.27e-246 678.0 COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,1RM8U@1236|Gammaproteobacteria,1XSJM@135623|Vibrionales 135623|Vibrionales M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids alr GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008784,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0034645,GO:0036361,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 5.1.1.1 ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 - R00401 RC00285 ko00000,ko00001,ko01000,ko01011 - - - Ala_racemase_C,Ala_racemase_N k141_31099_9 223926.28807745 6.91e-210 587.0 COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,1RPM2@1236|Gammaproteobacteria,1XTT6@135623|Vibrionales 135623|Vibrionales L it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k141_23902_1 1294265.JCM21738_1461 3.78e-87 271.0 COG5276@1|root,COG5276@2|Bacteria,1UUVN@1239|Firmicutes,4HBJX@91061|Bacilli,1ZE6M@1386|Bacillus 91061|Bacilli S LVIVD repeat - - - - - - - - - - - - LVIVD k141_25080_1 218284.CCDN010000001_gene1326 9.53e-99 291.0 COG1540@1|root,COG1540@2|Bacteria,1TR8X@1239|Firmicutes,4H9PF@91061|Bacilli,1ZC6W@1386|Bacillus 91061|Bacilli S Belongs to the UPF0271 (lamB) family ycsF - - ko:K07160 - - - - ko00000 - - - LamB_YcsF k141_26348_2 1279017.AQYJ01000028_gene2172 8.45e-155 449.0 COG3487@1|root,COG3487@2|Bacteria,1QTM3@1224|Proteobacteria,1RXQ2@1236|Gammaproteobacteria,468DH@72275|Alteromonadaceae 1236|Gammaproteobacteria P Imelysin - - - ko:K07231 - - - - ko00000 - - - Peptidase_M75 k141_21599_1 666686.B1NLA3E_04640 1.58e-12 68.2 COG0842@1|root,COG0842@2|Bacteria,1UZ26@1239|Firmicutes,4HENZ@91061|Bacilli,1ZDAD@1386|Bacillus 91061|Bacilli V COG0842 ABC-type multidrug transport system, permease component - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 k141_21599_2 666686.B1NLA3E_04645 1.34e-29 117.0 COG0842@1|root,COG0842@2|Bacteria,1V7HN@1239|Firmicutes,4HGE5@91061|Bacilli,1ZCVY@1386|Bacillus 91061|Bacilli V COG0842 ABC-type multidrug transport system, permease component - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 k141_22747_1 218284.CCDN010000004_gene3124 5.09e-32 117.0 COG0589@1|root,COG0589@2|Bacteria,1VH3X@1239|Firmicutes,4HNXN@91061|Bacilli,1ZCYJ@1386|Bacillus 91061|Bacilli T Universal stress protein nhaX - - - - - - - - - - - Usp k141_35774_1 218284.CCDN010000008_gene4197 2.33e-88 267.0 28NSI@1|root,2ZB4U@2|Bacteria,1UZ00@1239|Firmicutes,4HDBT@91061|Bacilli,1ZDNP@1386|Bacillus 91061|Bacilli - - ytlQ - - - - - - - - - - - NERD k141_1293_2 1453501.JELR01000002_gene1153 1.93e-27 109.0 COG2010@1|root,COG2010@2|Bacteria,1MV6D@1224|Proteobacteria,1RMYF@1236|Gammaproteobacteria,466XG@72275|Alteromonadaceae 1236|Gammaproteobacteria C Cytochrome C oxidase, cbb3-type, subunit III - - - - - - - - - - - - Cytochrom_C,Cytochrome_CBB3 k141_28733_1 1384049.CD29_10570 6.9e-33 130.0 COG0842@1|root,COG0842@2|Bacteria,1UZ26@1239|Firmicutes,4HENZ@91061|Bacilli,3IZ8Y@400634|Lysinibacillus 91061|Bacilli V ABC-2 type transporter - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 k141_7287_1 42565.FP66_08990 1.04e-28 105.0 COG2009@1|root,COG2009@2|Bacteria,1RIGZ@1224|Proteobacteria,1S5ZE@1236|Gammaproteobacteria,1XKF6@135619|Oceanospirillales 135619|Oceanospirillales C succinate dehydrogenase sdhC - - ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002 - - - Sdh_cyt k141_16796_1 218284.CCDN010000001_gene1 3.18e-89 267.0 COG4465@1|root,COG4465@2|Bacteria,1TS7A@1239|Firmicutes,4HA9U@91061|Bacilli,1ZBT9@1386|Bacillus 91061|Bacilli K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor codY GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0044424,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - ko:K03706 - - - - ko00000,ko03000 - - - CodY,HTH_CodY k141_12030_1 1116375.VEJY3_17221 1.42e-160 455.0 COG3608@1|root,COG3608@2|Bacteria,1MUAA@1224|Proteobacteria,1RNQQ@1236|Gammaproteobacteria,1XSB8@135623|Vibrionales 135623|Vibrionales S Succinylglutamate desuccinylase / Aspartoacylase family - - 3.5.1.125 ko:K15784 ko00260,ko01100,map00260,map01100 - R09801 RC00064,RC00300 ko00000,ko00001,ko01000 - - - AstE_AspA k141_10813_1 218284.CCDN010000003_gene2972 4.89e-121 362.0 COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1TPA1@1239|Firmicutes,4H9VC@91061|Bacilli,1ZASP@1386|Bacillus 91061|Bacilli J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation metG GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1g,tRNA_bind k141_23919_3 1279017.AQYJ01000027_gene1606 0.0 923.0 COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,1RNH8@1236|Gammaproteobacteria,464GS@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis ubiD GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008694,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.1.1.98 ko:K03182 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04985,R04986 RC00391 ko00000,ko00001,ko00002,ko01000 - - iECO111_1330.ECO111_4669 UbiD k141_7316_1 1348908.KI518590_gene2846 8.35e-75 236.0 28MVU@1|root,2ZB3B@2|Bacteria,1V0YH@1239|Firmicutes,4HBRC@91061|Bacilli,1ZM06@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - APH k141_9662_1 1120953.AUBH01000001_gene1202 3.36e-09 58.2 COG2819@1|root,COG2819@2|Bacteria,1RAB4@1224|Proteobacteria,1S2JK@1236|Gammaproteobacteria,466QX@72275|Alteromonadaceae 1236|Gammaproteobacteria S Putative esterase Z012_06880 - - - - - - - - - - - Esterase k141_9662_2 1279017.AQYJ01000028_gene2273 3.21e-81 253.0 COG3468@1|root,COG3468@2|Bacteria,1NTR4@1224|Proteobacteria,1T238@1236|Gammaproteobacteria,465K5@72275|Alteromonadaceae 1236|Gammaproteobacteria MU Protein of unknown function (DUF3014) - - - - - - - - - - - - DUF3014 k141_9662_3 1392490.JHZX01000001_gene2298 9.34e-233 652.0 COG0366@1|root,COG0366@2|Bacteria,4NEVK@976|Bacteroidetes,1HYB7@117743|Flavobacteriia 976|Bacteroidetes G alpha amylase, catalytic - - - - - - - - - - - - Alpha-amylase,Alpha-amylase_C,Malt_amylase_C k141_9662_4 1042377.AFPJ01000004_gene343 2.9e-294 811.0 COG0446@1|root,COG0446@2|Bacteria,1Q0P8@1224|Proteobacteria,1T1NQ@1236|Gammaproteobacteria,464PV@72275|Alteromonadaceae 1236|Gammaproteobacteria S Tryptophan halogenase - - 1.14.19.9 ko:K14266 ko00404,ko01130,map00404,map01130 M00789,M00790 R09570 RC00949 ko00000,ko00001,ko00002,ko01000 - - - Trp_halogenase k141_9662_6 1279017.AQYJ01000028_gene2267 4.51e-161 459.0 COG0837@1|root,COG0837@2|Bacteria,1MVFI@1224|Proteobacteria,1RNUY@1236|Gammaproteobacteria,464W6@72275|Alteromonadaceae 1236|Gammaproteobacteria F Belongs to the bacterial glucokinase family glk - 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Glucokinase k141_1324_1 1196031.ALEG01000005_gene5555 1.7e-30 115.0 2DJ1F@1|root,30CK1@2|Bacteria,1UA0V@1239|Firmicutes,4IK9E@91061|Bacilli,1ZG0K@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_9897_2 1265503.KB905160_gene2867 1.45e-79 248.0 COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,1RMJJ@1236|Gammaproteobacteria,2Q5WT@267889|Colwelliaceae 1236|Gammaproteobacteria T Response regulator receiver - - - ko:K02477 - - - - ko00000,ko02022 - - - LytTR,Response_reg k141_9897_3 722419.PH505_be00030 8.42e-36 130.0 COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,1RQDA@1236|Gammaproteobacteria,2Q15Y@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria T regulator of cell autolysis - - 2.7.13.3 ko:K08082 ko02020,map02020 M00493 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,His_kinase k141_32360_1 218284.CCDN010000001_gene51 3.49e-115 338.0 COG1561@1|root,COG1561@2|Bacteria,1TQHJ@1239|Firmicutes,4HAK9@91061|Bacilli,1ZCGE@1386|Bacillus 91061|Bacilli S stress-induced protein yloC - - - - - - - - - - - DUF1732,YicC_N k141_17008_1 1123376.AUIU01000011_gene837 1.25e-53 182.0 COG0205@1|root,COG0205@2|Bacteria,3J0Y1@40117|Nitrospirae 40117|Nitrospirae H Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions - - 2.7.1.11,2.7.1.90 ko:K21071 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 - R00756,R00764,R02073,R03236,R04779 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PFK k141_18246_1 42565.FP66_05260 0.000208 43.1 COG2056@1|root,COG2056@2|Bacteria,1N8U2@1224|Proteobacteria,1RRW5@1236|Gammaproteobacteria,1XIXD@135619|Oceanospirillales 135619|Oceanospirillales S sodium proton antiporter - - - ko:K07084 - - - - ko00000,ko02000 2.A.8.1.12 - - Na_H_antiport_2,Na_H_antiporter k141_18246_2 42565.FP66_05265 2.87e-22 96.7 COG1566@1|root,COG1566@2|Bacteria,1MU7I@1224|Proteobacteria,1RPV2@1236|Gammaproteobacteria,1XN4J@135619|Oceanospirillales 135619|Oceanospirillales V Biotin-lipoyl like - - - - - - - - - - - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 k141_12369_1 935261.JAGL01000020_gene412 2.76e-08 53.5 COG2246@1|root,COG2246@2|Bacteria,1NACX@1224|Proteobacteria,2UIN6@28211|Alphaproteobacteria 28211|Alphaproteobacteria S GtrA-like protein - - - - - - - - - - - - GtrA k141_12369_2 452662.SJA_C1-19470 2.73e-88 272.0 COG1215@1|root,COG1215@2|Bacteria,1QU2F@1224|Proteobacteria,2U0P8@28211|Alphaproteobacteria,2K007@204457|Sphingomonadales 204457|Sphingomonadales M Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 k141_473_1 1219076.N646_4717 9.93e-147 430.0 COG0601@1|root,COG1173@1|root,COG0601@2|Bacteria,COG1173@2|Bacteria,1R3VQ@1224|Proteobacteria,1RY4F@1236|Gammaproteobacteria,1XTGP@135623|Vibrionales 135623|Vibrionales P Binding-protein-dependent transport system inner membrane component - - - ko:K02033,ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 k141_7458_1 218284.CCDN010000001_gene979 4.72e-41 136.0 2E54T@1|root,32ZXQ@2|Bacteria,1VFDB@1239|Firmicutes,4HNU1@91061|Bacilli,1ZIWH@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2627) yqzF - - - - - - - - - - - DUF2627 k141_1510_1 218284.CCDN010000002_gene2206 6.59e-107 311.0 COG1595@1|root,COG1595@2|Bacteria,1V4B8@1239|Firmicutes,4HHCY@91061|Bacilli,1ZFQN@1386|Bacillus 91061|Bacilli K Sigma-70, region 4 - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4,Sigma70_r4_2 k141_1510_2 218284.CCDN010000002_gene2205 1.33e-107 317.0 COG5662@1|root,COG5662@2|Bacteria,1V446@1239|Firmicutes,4HHFJ@91061|Bacilli,1ZHD5@1386|Bacillus 91061|Bacilli K Anti-sigma-K factor rskA - - - - - - - - - - - - RskA,zf-HC2 k141_25343_2 1294265.JCM21738_2010 6.3e-51 170.0 COG0674@1|root,COG0674@2|Bacteria,1TSSC@1239|Firmicutes,4HA8C@91061|Bacilli,1ZF89@1386|Bacillus 91061|Bacilli C Pyruvate:ferredoxin oxidoreductase core domain II - - 1.2.7.11,1.2.7.3 ko:K00174 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - PFOR_II,POR_N k141_31276_1 1279017.AQYJ01000029_gene3491 3.55e-46 150.0 COG3141@1|root,COG3141@2|Bacteria,1N26M@1224|Proteobacteria,1SCRN@1236|Gammaproteobacteria,468R9@72275|Alteromonadaceae 1236|Gammaproteobacteria S YebG protein - - - ko:K09918 - - - - ko00000 - - - YebG k141_33669_1 1279017.AQYJ01000021_gene2947 2.7e-49 174.0 COG1714@1|root,COG2214@1|root,COG1714@2|Bacteria,COG2214@2|Bacteria,1NGQY@1224|Proteobacteria,1S3RD@1236|Gammaproteobacteria 1236|Gammaproteobacteria O DnaJ molecular chaperone homology domain - - - ko:K07126 - - - - ko00000 - - - RDD k141_26711_1 218284.CCDN010000001_gene1358 1.07e-139 408.0 COG0488@1|root,COG0488@2|Bacteria,1TPW0@1239|Firmicutes,4HATH@91061|Bacilli,1ZBVV@1386|Bacillus 91061|Bacilli S COG0488 ATPase components of ABC transporters with duplicated ATPase domains ykpA - - - - - - - - - - - ABC_tran,ABC_tran_Xtn k141_21777_1 1122921.KB898188_gene237 5.68e-30 117.0 COG0122@1|root,COG0122@2|Bacteria,1TQAF@1239|Firmicutes,4HBYM@91061|Bacilli,26S4B@186822|Paenibacillaceae 91061|Bacilli L 8-oxoguanine DNA glycosylase alkA - 3.2.2.21 ko:K01247,ko:K13529 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03000,ko03400 - - - AlkA_N,HhH-GPD,OGG_N k141_21777_2 1408254.T458_24235 6.67e-105 306.0 COG2169@1|root,COG2169@2|Bacteria,1V3Y7@1239|Firmicutes,4HCPZ@91061|Bacilli,274D4@186822|Paenibacillaceae 91061|Bacilli K Metal binding domain of Ada adaA1 - - ko:K13530 - - - - ko00000,ko01000,ko03000,ko03400 - - - Ada_Zn_binding,HTH_18,HTH_AraC k141_21777_4 1307436.PBF_18114 3.9e-60 194.0 COG4858@1|root,COG4858@2|Bacteria,1V8U0@1239|Firmicutes,4HIMP@91061|Bacilli,1ZFXH@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_4032_1 218284.CCDN010000001_gene571 6.87e-103 304.0 COG0672@1|root,COG0672@2|Bacteria,1TQIA@1239|Firmicutes,4HCJZ@91061|Bacilli,1ZDYA@1386|Bacillus 91061|Bacilli P COG0672 High-affinity Fe2 Pb2 permease - - - ko:K07243 - - - - ko00000,ko02000 2.A.108.1,2.A.108.2 - - FTR1 k141_15826_1 1042377.AFPJ01000013_gene1738 2.33e-86 262.0 COG2738@1|root,COG2738@2|Bacteria,1RDJH@1224|Proteobacteria,1S4QY@1236|Gammaproteobacteria,46AKY@72275|Alteromonadaceae 1236|Gammaproteobacteria S Putative neutral zinc metallopeptidase - - - ko:K06973 - - - - ko00000 - - - Zn_peptidase_2 k141_5133_2 1116375.VEJY3_17226 2.29e-295 805.0 COG0006@1|root,COG0006@2|Bacteria,1MWUT@1224|Proteobacteria,1RZSD@1236|Gammaproteobacteria,1XU52@135623|Vibrionales 135623|Vibrionales E Creatinase/Prolidase N-terminal domain - - 3.5.4.44 ko:K15783 ko00260,ko01100,map00260,map01100 - R09800 RC02661 ko00000,ko00001,ko01000 - - - Creatinase_N,Peptidase_M24 k141_5133_3 1116375.VEJY3_17231 3.32e-151 433.0 COG1609@1|root,COG1609@2|Bacteria,1N4ND@1224|Proteobacteria,1RNR5@1236|Gammaproteobacteria,1XVKJ@135623|Vibrionales 135623|Vibrionales K Transcriptional regulator, LacI family - - - ko:K02529,ko:K03487 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 k141_18275_2 283699.D172_0727 6.07e-28 110.0 COG2267@1|root,COG2267@2|Bacteria,1MZG8@1224|Proteobacteria,1RMW1@1236|Gammaproteobacteria,2Q1YQ@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria I Serine aminopeptidase, S33 - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 k141_13575_1 340177.Cag_0107 6.62e-75 237.0 COG0505@1|root,COG0505@2|Bacteria,1FDK4@1090|Chlorobi 1090|Chlorobi F Belongs to the CarA family carA - 6.3.5.5 ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_sm_chain,GATase k141_9935_1 218284.CCDN010000002_gene2822 8.31e-52 173.0 COG1595@1|root,COG1595@2|Bacteria,1VEMV@1239|Firmicutes,4HP80@91061|Bacilli,1ZFIF@1386|Bacillus 91061|Bacilli K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_9935_2 218284.CCDN010000002_gene2823 5.83e-126 360.0 COG0740@1|root,COG0740@2|Bacteria,1TQ91@1239|Firmicutes,4HA8J@91061|Bacilli,1ZD1N@1386|Bacillus 91061|Bacilli OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins clpP1 - 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 - - - ko00000,ko00001,ko01000,ko01002 - - - CLP_protease k141_17028_2 42565.FP66_01465 7.46e-43 139.0 COG2906@1|root,COG2906@2|Bacteria,1NGGY@1224|Proteobacteria,1SGGM@1236|Gammaproteobacteria,1XMP1@135619|Oceanospirillales 135619|Oceanospirillales P Bacterioferritin-associated ferredoxin bfd - - ko:K02192 - - - - ko00000 - - - Fer2_BFD k141_17028_3 42565.FP66_01470 2.03e-58 182.0 COG1714@1|root,COG1714@2|Bacteria,1N7R6@1224|Proteobacteria,1SCCT@1236|Gammaproteobacteria,1XKP5@135619|Oceanospirillales 135619|Oceanospirillales S membrane protein domain - - - - - - - - - - - - RDD k141_11101_1 1196031.ALEG01000065_gene64 2.55e-110 324.0 COG0039@1|root,COG0039@2|Bacteria,1TPSY@1239|Firmicutes,4HB0Z@91061|Bacilli,1ZD23@1386|Bacillus 91061|Bacilli C Catalyzes the reversible oxidation of malate to oxaloacetate mdh - 1.1.1.27,1.1.1.37 ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740 R00342,R00703,R01000,R03104,R07136 RC00031,RC00044 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Ldh_1_C,Ldh_1_N k141_7478_2 908340.HMPREF9406_0499 4.59e-44 153.0 COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,248U9@186801|Clostridia,36ESA@31979|Clostridiaceae 186801|Clostridia GK ROK family glcK - 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - ROK k141_32374_1 218284.CCDN010000001_gene1243 2.16e-36 129.0 COG1028@1|root,COG1028@2|Bacteria,1TSQV@1239|Firmicutes,4HB3U@91061|Bacilli,1ZC75@1386|Bacillus 91061|Bacilli IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) ytkK - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 k141_8754_1 1288826.MSNKSG1_04001 1.11e-17 80.9 COG1211@1|root,COG1211@2|Bacteria,1MY3B@1224|Proteobacteria,1S21S@1236|Gammaproteobacteria,466GI@72275|Alteromonadaceae 1236|Gammaproteobacteria I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) ispD GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0050518,GO:0070567,GO:0071704,GO:1901576 2.7.7.60 ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05633 RC00002 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b2747,iBWG_1329.BWG_2483,iEC55989_1330.EC55989_3019,iECDH10B_1368.ECDH10B_2915,iECDH1ME8569_1439.ECDH1ME8569_2657,iECIAI1_1343.ECIAI1_2848,iECO103_1326.ECO103_3289,iECO111_1330.ECO111_3471,iECO26_1355.ECO26_3816,iECSE_1348.ECSE_2999,iECW_1372.ECW_m2953,iEKO11_1354.EKO11_1022,iEcDH1_1363.EcDH1_0941,iEcE24377_1341.EcE24377A_3048,iEcHS_1320.EcHS_A2885,iEcolC_1368.EcolC_0965,iJO1366.b2747,iJR904.b2747,iPC815.YPO3361,iSBO_1134.SBO_2773,iSDY_1059.SDY_2946,iSSON_1240.SSON_2895,iSbBS512_1146.SbBS512_E3127,iUMNK88_1353.UMNK88_3422,iWFL_1372.ECW_m2953,iY75_1357.Y75_RS14300 IspD k141_8754_2 1121943.KB900004_gene2890 1.14e-49 162.0 COG0245@1|root,COG0245@2|Bacteria,1MVHA@1224|Proteobacteria,1S3RQ@1236|Gammaproteobacteria,1XJPI@135619|Oceanospirillales 135619|Oceanospirillales I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) ispF - 4.6.1.12 ko:K01770 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05637 RC00002,RC01440 ko00000,ko00001,ko00002,ko01000 - - - YgbB k141_30010_1 1116375.VEJY3_13880 2.4e-91 285.0 COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1MUQV@1224|Proteobacteria,1RN0Q@1236|Gammaproteobacteria,1XSFU@135623|Vibrionales 135623|Vibrionales T COG2199 FOG GGDEF domain csrD - - ko:K18765 - - - - ko00000,ko03019 - - - EAL,GAPES4,GGDEF k141_12391_1 223926.28807720 3.46e-78 236.0 COG2197@1|root,COG2197@2|Bacteria,1R531@1224|Proteobacteria,1S18M@1236|Gammaproteobacteria,1XVDS@135623|Vibrionales 135623|Vibrionales K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - ko:K04333 ko02026,map02026 - - - ko00000,ko00001,ko03000 - - - GerE k141_12391_2 1454202.PPBDW_110010___1 1.37e-87 261.0 COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,1S3WP@1236|Gammaproteobacteria,1XSPW@135623|Vibrionales 135623|Vibrionales L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576 - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k141_12391_3 223926.28807718 2.81e-274 764.0 COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1MUQV@1224|Proteobacteria,1RN0Q@1236|Gammaproteobacteria,1XSFU@135623|Vibrionales 135623|Vibrionales T COG2199 FOG GGDEF domain csrD - - ko:K18765 - - - - ko00000,ko03019 - - - EAL,GAPES4,GGDEF k141_21795_1 1042377.AFPJ01000028_gene2163 2.63e-103 327.0 COG1729@1|root,COG1729@2|Bacteria,1MX82@1224|Proteobacteria,1T32S@1236|Gammaproteobacteria,465Q0@72275|Alteromonadaceae 1236|Gammaproteobacteria O protein conserved in bacteria - - - - - - - - - - - - TPR_16,TPR_6,TPR_8,YfiO k141_37176_1 1294265.JCM21738_5158 9.33e-200 584.0 COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,4H9T3@91061|Bacilli,1ZCIC@1386|Bacillus 91061|Bacilli L DNA polymerase dnaE - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon k141_11102_2 243277.VC_A0930 1.89e-16 77.4 COG2354@1|root,COG2354@2|Bacteria,1MVYU@1224|Proteobacteria,1RMUZ@1236|Gammaproteobacteria,1XTCV@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria yedI - - ko:K09781 - - - - ko00000 - - - DUF808 k141_495_2 272123.Anacy_5597 3.17e-33 125.0 COG1075@1|root,COG1075@2|Bacteria,1G5F7@1117|Cyanobacteria,1HMFZ@1161|Nostocales 1117|Cyanobacteria S COGs COG1075 acetyltransferase and hydrolase with the alpha beta hydrolase fold - - 3.1.1.3 ko:K01046 ko00561,ko01100,map00561,map01100 M00098 R02250,R02687 RC00020,RC00037,RC00041,RC00094 ko00000,ko00001,ko00002,ko01000 - - - Abhydrolase_1,Abhydrolase_6,Lipase_2 k141_495_4 1453501.JELR01000002_gene765 0.0 1179.0 COG1680@1|root,COG1680@2|Bacteria,1MWHS@1224|Proteobacteria,1RRQF@1236|Gammaproteobacteria,46627@72275|Alteromonadaceae 1236|Gammaproteobacteria V COG1680 Beta-lactamase class C and other penicillin binding - - - - - - - - - - - - ASH,Beta-lactamase k141_13576_1 997296.PB1_08157 2.12e-179 509.0 COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,4HAT6@91061|Bacilli,1ZB62@1386|Bacillus 91061|Bacilli C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits atpD - 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_N k141_6441_1 42565.FP66_04735 9.25e-80 252.0 COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,1RMTB@1236|Gammaproteobacteria,1XIAV@135619|Oceanospirillales 135619|Oceanospirillales O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions groL - - ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 - - - Cpn60_TCP1 k141_1534_1 218284.CCDN010000002_gene2239 3.02e-69 223.0 COG1966@1|root,COG1966@2|Bacteria,1TQN8@1239|Firmicutes,4H9SU@91061|Bacilli,1ZC6K@1386|Bacillus 91061|Bacilli T Carbon starvation protein cstA - - - - - - - - - - - CstA,CstA_5TM k141_33705_1 1453501.JELR01000002_gene340 7.68e-10 60.1 COG3182@1|root,COG3182@2|Bacteria,1MW2S@1224|Proteobacteria,1RQYY@1236|Gammaproteobacteria,46CKU@72275|Alteromonadaceae 1236|Gammaproteobacteria S PepSY-associated TM region - - - - - - - - - - - - PepSY,PepSY_TM k141_25371_1 1280001.BAOA01000078_gene3158 1.13e-67 210.0 COG1842@1|root,COG1842@2|Bacteria,1NC7S@1224|Proteobacteria,1RS0G@1236|Gammaproteobacteria,1XUJH@135623|Vibrionales 135623|Vibrionales KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription pspA - - ko:K03969 - - - - ko00000 - - - PspA_IM30 k141_25371_2 223926.28806160 1.07e-220 611.0 COG2204@1|root,COG2204@2|Bacteria,1MWW5@1224|Proteobacteria,1RND4@1236|Gammaproteobacteria,1XUMP@135623|Vibrionales 135623|Vibrionales K COG1221 Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain pspF - - ko:K03974 - - - - ko00000,ko03000 - - - HTH_8,Sigma54_activat k141_9937_1 1116375.VEJY3_10905 3.04e-87 269.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1XTGI@135623|Vibrionales 135623|Vibrionales T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains luxO GO:0000156,GO:0000160,GO:0003674,GO:0003700,GO:0006355,GO:0007154,GO:0007165,GO:0008150,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0023052,GO:0031323,GO:0031326,GO:0035556,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051716,GO:0060089,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 - ko:K10912 ko02020,ko02024,ko05111,map02020,map02024,map05111 M00513 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat k141_9937_2 223926.28807091 2.39e-46 152.0 COG2198@1|root,COG2198@2|Bacteria,1NH5B@1224|Proteobacteria,1SGR8@1236|Gammaproteobacteria,1XYAG@135623|Vibrionales 135623|Vibrionales T Phosphorelay protein which receives a sensory signal from a sensor kinase and transmit it to LuxO. At low cell density, a phosphoryl group is transferred from the sensor kinase, probably on His-56 and this phosphoryl group is further transferred to LuxO luxU GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008218,GO:0009372,GO:0009987,GO:0023052,GO:0044237,GO:0044764,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051716,GO:0065007 - ko:K10911 ko02020,ko02024,ko05111,map02020,map02024,map05111 M00513 - - ko00000,ko00001,ko00002,ko02022 - - - Hpt k141_9937_3 243277.VC_1023 3.84e-29 112.0 COG0391@1|root,COG0391@2|Bacteria,1NW3K@1224|Proteobacteria,1RQP9@1236|Gammaproteobacteria,1XUN3@135623|Vibrionales 135623|Vibrionales S Required for morphogenesis under gluconeogenic growth conditions ybhK - - - - - - - - - - - UPF0052 k141_34832_1 1279017.AQYJ01000027_gene1591 9.88e-167 519.0 COG0643@1|root,COG0784@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,4650G@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0643 Chemotaxis protein histidine kinase and related kinases chpA - - ko:K02487,ko:K06596 ko02020,ko02025,map02020,map02025 M00507 - - ko00000,ko00001,ko00002,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg k141_34832_2 1042377.AFPJ01000032_gene2818 5.9e-79 238.0 COG0835@1|root,COG0835@2|Bacteria,1NA8G@1224|Proteobacteria,1S8Q6@1236|Gammaproteobacteria,46CTM@72275|Alteromonadaceae 1236|Gammaproteobacteria NT CheW-like domain - - - ko:K06598 ko02020,ko02025,map02020,map02025 - - - ko00000,ko00001,ko02035 - - - CheW k141_34832_4 1453501.JELR01000002_gene949 9.82e-223 618.0 COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,1RN8S@1236|Gammaproteobacteria,465IC@72275|Alteromonadaceae 1236|Gammaproteobacteria NU COG4972 Tfp pilus assembly protein, ATPase PilM pilM - - ko:K02662 - - - - ko00000,ko02035,ko02044 - - - PilM_2 k141_34832_5 1453501.JELR01000002_gene948 8.22e-109 316.0 COG3166@1|root,COG3166@2|Bacteria,1RF1S@1224|Proteobacteria,1S3S0@1236|Gammaproteobacteria,467DK@72275|Alteromonadaceae 1236|Gammaproteobacteria NU COG3166 Tfp pilus assembly protein PilN pilN - - ko:K02663 - - - - ko00000,ko02035,ko02044 - - - PilN k141_34832_6 1042377.AFPJ01000032_gene2814 1e-126 362.0 COG3167@1|root,COG3167@2|Bacteria,1RBGW@1224|Proteobacteria,1S3XQ@1236|Gammaproteobacteria,466YT@72275|Alteromonadaceae 1236|Gammaproteobacteria NU COG3167 Tfp pilus assembly protein PilO pilO - - ko:K02664 - - - - ko00000,ko02035,ko02044 - - - PilO k141_34832_7 1453501.JELR01000002_gene946 2.26e-99 291.0 COG3168@1|root,COG3168@2|Bacteria,1RI6V@1224|Proteobacteria,1S6VJ@1236|Gammaproteobacteria,467HE@72275|Alteromonadaceae 1236|Gammaproteobacteria NU pilus assembly protein PilP pilP - - ko:K02665 - - - - ko00000,ko02035,ko02044 - - - PilP k141_34832_8 1042377.AFPJ01000032_gene2812 1.41e-186 541.0 COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,1RN3Z@1236|Gammaproteobacteria,465HK@72275|Alteromonadaceae 1236|Gammaproteobacteria U COG4796 Type II secretory pathway, component HofQ pilQ GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0015976,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 - ko:K02507,ko:K02666 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - AMIN,STN,Secretin,Secretin_N k141_17030_1 1347086.CCBA010000004_gene4405 1.69e-84 271.0 COG1404@1|root,COG1404@2|Bacteria,1TQRU@1239|Firmicutes,4HAZA@91061|Bacilli,1ZAZK@1386|Bacillus 91061|Bacilli O Belongs to the peptidase S8 family - - - - - - - - - - - - Inhibitor_I9,PA,PPC,Peptidase_S8,SLH k141_497_1 1042377.AFPJ01000020_gene2098 5.64e-92 283.0 COG2067@1|root,COG2067@2|Bacteria,1MUU4@1224|Proteobacteria,1RQZJ@1236|Gammaproteobacteria,465E0@72275|Alteromonadaceae 1236|Gammaproteobacteria I Long-chain fatty acid fadL GO:0003674,GO:0005215,GO:0005319,GO:0005324,GO:0005342,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006820,GO:0006869,GO:0008028,GO:0008150,GO:0008509,GO:0008514,GO:0009279,GO:0010876,GO:0015075,GO:0015245,GO:0015267,GO:0015288,GO:0015318,GO:0015483,GO:0015711,GO:0015718,GO:0015849,GO:0015908,GO:0015909,GO:0016020,GO:0019867,GO:0022803,GO:0022829,GO:0022834,GO:0022836,GO:0022857,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0034220,GO:0044462,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098656,GO:1903825,GO:1905039 - ko:K06076 - - - - ko00000,ko02000 1.B.9 - iECs_1301.ECs3227,iG2583_1286.G2583_2880,iZ_1308.Z3608 Toluene_X k141_12393_2 218284.CCDN010000001_gene1205 3.47e-48 160.0 COG2755@1|root,COG2755@2|Bacteria,1UZYP@1239|Firmicutes,4HDQY@91061|Bacilli,1ZEFB@1386|Bacillus 91061|Bacilli E COG2755 Lysophospholipase L1 and related esterases - - - - - - - - - - - - Lipase_GDSL_2 k141_25372_1 218284.CCDN010000001_gene723 2.96e-94 296.0 COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,4H9M4@91061|Bacilli,1ZBWR@1386|Bacillus 91061|Bacilli S Competence protein ComEC comEC - - ko:K02238 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - Competence,DUF4131,Lactamase_B k141_30011_1 1042377.AFPJ01000004_gene416 1.63e-87 264.0 2E02Y@1|root,32VRV@2|Bacteria,1N1HZ@1224|Proteobacteria,1S93X@1236|Gammaproteobacteria,4688F@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - SPOR k141_21796_1 580327.Tthe_2485 4.3e-47 169.0 COG1236@1|root,COG1236@2|Bacteria,1TQBH@1239|Firmicutes,248QR@186801|Clostridia,42EZX@68295|Thermoanaerobacterales 186801|Clostridia J PFAM RNA-metabolising metallo-beta-lactamase - - - ko:K07576 - - - - ko00000 - - - Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL k141_5135_1 1279017.AQYJ01000026_gene307 2.41e-176 506.0 COG0845@1|root,COG0845@2|Bacteria,1R3R4@1224|Proteobacteria,1RNSG@1236|Gammaproteobacteria,4666Y@72275|Alteromonadaceae 1236|Gammaproteobacteria M HlyD family secretion protein - - - ko:K13408 ko04626,map04626 M00339 - - ko00000,ko00001,ko00002,ko02000,ko02044 8.A.1 - - Biotin_lipoyl_2,HlyD_3 k141_5135_2 1279017.AQYJ01000026_gene306 2.87e-35 134.0 COG2274@1|root,COG2274@2|Bacteria,1R2T0@1224|Proteobacteria,1SBE1@1236|Gammaproteobacteria,464I6@72275|Alteromonadaceae 1236|Gammaproteobacteria V COG2274 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain cvaB - - ko:K06147,ko:K13409 ko02010,ko04626,map02010,map04626 M00339 - - ko00000,ko00001,ko00002,ko02000,ko02044 3.A.1.106,3.A.1.109,3.A.1.110,3.A.1.21 - - ABC_membrane,ABC_tran,Peptidase_C39,cNMP_binding k141_34833_1 42565.FP66_09455 3.72e-78 237.0 COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,1RNNY@1236|Gammaproteobacteria,1XI7Z@135619|Oceanospirillales 135619|Oceanospirillales F Catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis purC - 6.3.2.6 ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04591 RC00064,RC00162 ko00000,ko00001,ko00002,ko01000 - - - SAICAR_synt k141_13578_1 218284.CCDN010000001_gene119 1.66e-144 414.0 COG2340@1|root,COG2340@2|Bacteria,1UYZ4@1239|Firmicutes,4HBTC@91061|Bacilli,1ZCGK@1386|Bacillus 91061|Bacilli S protein with SCP PR1 domains ylbC - - - - - - - - - - - CAP,CAP_assoc_N k141_2760_1 1279017.AQYJ01000025_gene568 2.11e-213 612.0 COG0642@1|root,COG0784@1|root,COG0642@2|Bacteria,COG0784@2|Bacteria,1R4TJ@1224|Proteobacteria,1RQKQ@1236|Gammaproteobacteria,4671J@72275|Alteromonadaceae 1236|Gammaproteobacteria T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,Response_reg k141_2760_2 1390370.O203_09330 3.73e-194 550.0 COG0477@1|root,COG2814@2|Bacteria,1MV8D@1224|Proteobacteria,1RNF0@1236|Gammaproteobacteria,1YF1S@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 k141_2760_3 1232683.ADIMK_2877 2.13e-192 539.0 COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,1RMBM@1236|Gammaproteobacteria,464DU@72275|Alteromonadaceae 1236|Gammaproteobacteria G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family gap - 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N k141_2760_4 1166130.H650_02310 4.34e-27 103.0 COG0640@1|root,COG0640@2|Bacteria,1MZT1@1224|Proteobacteria,1SAI5@1236|Gammaproteobacteria,3X2J2@547|Enterobacter 1236|Gammaproteobacteria K helix_turn_helix, Arsenical Resistance Operon Repressor arsR - - ko:K03892 - - - - ko00000,ko03000 - - - HTH_5,LMWPc k141_2760_6 1279017.AQYJ01000025_gene548 1.46e-174 489.0 COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,1RN4H@1236|Gammaproteobacteria,465AT@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG0708 Exonuclease III xthA GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008853,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.11.2 ko:K01142 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Exo_endo_phos k141_2760_7 1279017.AQYJ01000025_gene547 2.54e-193 555.0 COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,1RMSR@1236|Gammaproteobacteria,4646K@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the peptidase S41A family prc GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016787,GO:0019538,GO:0023052,GO:0030163,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - BAGE,DUF3340,PDZ,Peptidase_S41 k141_4042_1 223926.28807343 1.18e-183 514.0 COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,1RNMZ@1236|Gammaproteobacteria,1XSQ4@135623|Vibrionales 135623|Vibrionales H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein apbE - 2.7.1.180 ko:K03734 - - - - ko00000,ko01000 - - - ApbE k141_4042_2 674977.VMC_17380 5.25e-298 812.0 COG2871@1|root,COG2871@2|Bacteria,1QTUV@1224|Proteobacteria,1RPG5@1236|Gammaproteobacteria,1XTCQ@135623|Vibrionales 135623|Vibrionales C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway nqrF GO:0000166,GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030001,GO:0030964,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0044425,GO:0048037,GO:0050136,GO:0050660,GO:0050662,GO:0051179,GO:0051234,GO:0051536,GO:0051537,GO:0051540,GO:0055114,GO:0071949,GO:0097159,GO:0098796,GO:1901265,GO:1901363,GO:1902494 1.6.5.8 ko:K00351 - - - - ko00000,ko01000 - - - FAD_binding_6,Fer2,NAD_binding_1 k141_4042_3 1280001.BAOA01000081_gene2951 8.45e-131 372.0 COG2209@1|root,COG2209@2|Bacteria,1R33S@1224|Proteobacteria,1RMWV@1236|Gammaproteobacteria,1XSTK@135623|Vibrionales 135623|Vibrionales C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol nqrE GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030001,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0051179,GO:0051234,GO:0055114,GO:0098796,GO:1902494 1.6.5.8 ko:K00350 - - - - ko00000,ko01000 - - - Rnf-Nqr k141_4042_4 675814.VIC_000690 2.05e-137 390.0 COG1347@1|root,COG1347@2|Bacteria,1MUZR@1224|Proteobacteria,1RNFE@1236|Gammaproteobacteria,1XSX6@135623|Vibrionales 135623|Vibrionales C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol nqrD GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030001,GO:0030964,GO:0032991,GO:0044425,GO:0044464,GO:0050136,GO:0051179,GO:0051234,GO:0055114,GO:0071944,GO:0098796,GO:1902494 1.6.5.8 ko:K00349 - - - - ko00000,ko01000 - - - Rnf-Nqr k141_4042_5 1116375.VEJY3_12225 6.11e-180 501.0 COG2869@1|root,COG2869@2|Bacteria,1MVDI@1224|Proteobacteria,1RR85@1236|Gammaproteobacteria,1XUPV@135623|Vibrionales 135623|Vibrionales C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol nqrC GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008152,GO:0010181,GO:0015672,GO:0016491,GO:0016651,GO:0016655,GO:0030001,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0051179,GO:0051234,GO:0055114,GO:0097159,GO:0097367,GO:1901265,GO:1901363 1.6.5.8 ko:K00348 - - - - ko00000,ko01000 - - - FMN_bind k141_4042_6 1116375.VEJY3_12230 1.66e-309 842.0 COG1805@1|root,COG1805@2|Bacteria,1QTUU@1224|Proteobacteria,1RMGH@1236|Gammaproteobacteria,1XUP5@135623|Vibrionales 135623|Vibrionales C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol nqrB GO:0000166,GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008144,GO:0008150,GO:0008152,GO:0010181,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0019842,GO:0030001,GO:0030964,GO:0032553,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0044425,GO:0044464,GO:0048037,GO:0050136,GO:0050662,GO:0051179,GO:0051234,GO:0055114,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:1901265,GO:1901363,GO:1902444,GO:1902494 1.6.5.8 ko:K00347 - - - - ko00000,ko01000 - - - NQR2_RnfD_RnfE k141_4042_7 674977.VMC_17330 0.0 904.0 COG1726@1|root,COG1726@2|Bacteria,1MU36@1224|Proteobacteria,1RPU1@1236|Gammaproteobacteria,1XTB1@135623|Vibrionales 135623|Vibrionales C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol nqrA GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030001,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0051179,GO:0051234,GO:0055114,GO:0098796,GO:1902494 1.6.5.8 ko:K00346 - - - - ko00000,ko01000 - - - NQRA,NQRA_SLBB k141_4042_8 1116375.VEJY3_12240 2.39e-68 206.0 COG0271@1|root,COG0271@2|Bacteria,1MZG5@1224|Proteobacteria,1S91G@1236|Gammaproteobacteria,1XYE9@135623|Vibrionales 135623|Vibrionales T Belongs to the BolA IbaG family bolA GO:0008150,GO:0008360,GO:0022603,GO:0022604,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008 - ko:K05527 - - - - ko00000,ko03000 - - - BolA k141_4042_9 223926.28807351 7.91e-252 694.0 COG2813@1|root,COG2813@2|Bacteria,1NEMR@1224|Proteobacteria,1RMXE@1236|Gammaproteobacteria,1XU8G@135623|Vibrionales 135623|Vibrionales J Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA rlmG GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052916,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.174 ko:K11391 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - MTS,MTS_N k141_4042_10 1219076.N646_1471 2.3e-110 320.0 COG3056@1|root,COG3056@2|Bacteria,1MZ1N@1224|Proteobacteria,1RPG1@1236|Gammaproteobacteria,1XTP6@135623|Vibrionales 135623|Vibrionales M lipoprotein VV2594 - - ko:K07286 - - - - ko00000 - - - Lipoprotein_16 k141_4042_11 223926.28807353 1.08e-111 322.0 COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,1RP9U@1236|Gammaproteobacteria,1XTSG@135623|Vibrionales 135623|Vibrionales M PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides rotA - 5.2.1.8 ko:K03767 ko01503,ko04217,map01503,map04217 - - - ko00000,ko00001,ko01000,ko03110,ko04147 - - - Pro_isomerase k141_4042_12 1219076.N646_1473 7.08e-298 815.0 COG2211@1|root,COG2211@2|Bacteria,1QTSE@1224|Proteobacteria,1T1FN@1236|Gammaproteobacteria,1XSVM@135623|Vibrionales 135623|Vibrionales G COG0477 Permeases of the major facilitator superfamily ampG - - ko:K08218 ko01501,map01501 M00628 - - ko00000,ko00001,ko00002,ko02000 2.A.1.25 - - MFS_1 k141_35966_1 1120973.AQXL01000100_gene1124 1.17e-59 205.0 COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,4HB12@91061|Bacilli,2786P@186823|Alicyclobacillaceae 91061|Bacilli L DNA helicase pcrA - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C k141_20538_2 1279017.AQYJ01000026_gene230 0.0 977.0 COG4776@1|root,COG4776@2|Bacteria,1P563@1224|Proteobacteria,1RP5G@1236|Gammaproteobacteria,46DF9@72275|Alteromonadaceae 1236|Gammaproteobacteria K RNB rnb GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0008859,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360,GO:1901361,GO:1901575 3.1.13.1 ko:K01147 - - - - ko00000,ko01000,ko03016 - - - OB_RNB,RNB,S1 k141_9940_2 218284.CCDN010000001_gene946 3.27e-26 106.0 COG0209@1|root,COG0209@2|Bacteria,1TPFH@1239|Firmicutes,4HA07@91061|Bacilli,1ZCST@1386|Bacillus 91061|Bacilli F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen nrdZ - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_lgC,Ribonuc_red_lgN k141_18276_2 1279017.AQYJ01000029_gene3314 1.26e-248 689.0 COG1883@1|root,COG1883@2|Bacteria,1MV0G@1224|Proteobacteria,1RP3W@1236|Gammaproteobacteria,464KB@72275|Alteromonadaceae 1236|Gammaproteobacteria C Na transporting methylmalonyl-CoA oxaloacetate decarboxylase beta subunit oadB GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0008948,GO:0009987,GO:0015980,GO:0016020,GO:0016829,GO:0016830,GO:0016831,GO:0044237,GO:0044464,GO:0055114,GO:0071944 4.1.1.3 ko:K01572 ko00620,ko01100,map00620,map01100 - R00217 RC00040 ko00000,ko00001,ko01000,ko02000 3.B.1.1.1 - - OAD_beta k141_8760_1 861299.J421_1260 1.73e-40 149.0 COG0612@1|root,COG0612@2|Bacteria,1ZT1J@142182|Gemmatimonadetes 142182|Gemmatimonadetes S Insulinase (Peptidase family M16) - - - - - - - - - - - - Peptidase_M16,Peptidase_M16_C k141_10174_1 574375.BAGA_18890 5.97e-77 241.0 2DB75@1|root,2Z7JY@2|Bacteria,1TSI8@1239|Firmicutes,4IRVK@91061|Bacilli,1ZJU4@1386|Bacillus 91061|Bacilli S Phage major capsid protein E - - - - - - - - - - - - Phage_cap_E k141_687_1 1294265.JCM21738_5412 8.54e-115 343.0 COG4187@1|root,COG4187@2|Bacteria,1TQQ7@1239|Firmicutes,4HABT@91061|Bacilli,1ZCEE@1386|Bacillus 91061|Bacilli E arginine degradation protein rocB - - - - - - - - - - - Peptidase_M20 k141_27721_1 218284.CCDN010000001_gene1737 8.99e-40 138.0 COG0344@1|root,COG0344@2|Bacteria,1VAFC@1239|Firmicutes,4HMJZ@91061|Bacilli,1ZHAN@1386|Bacillus 91061|Bacilli I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP plsY1 - 2.3.1.15 ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - G3P_acyltransf k141_37318_1 1501391.LG35_02625 1.99e-12 68.2 COG1985@1|root,COG1985@2|Bacteria,4NMMD@976|Bacteroidetes,2FSCX@200643|Bacteroidia 976|Bacteroidetes H RibD C-terminal domain - - - - - - - - - - - - RibD_C k141_26937_1 1453501.JELR01000001_gene2632 1.12e-61 204.0 COG1196@1|root,COG1196@2|Bacteria,1NPJ3@1224|Proteobacteria,1SGPQ@1236|Gammaproteobacteria,46C3R@72275|Alteromonadaceae 1236|Gammaproteobacteria D nuclear chromosome segregation - - - - - - - - - - - - - k141_15966_1 1123073.KB899241_gene3172 1.71e-25 102.0 COG2227@1|root,COG2227@2|Bacteria,1N6SE@1224|Proteobacteria,1SCC1@1236|Gammaproteobacteria,1X6AF@135614|Xanthomonadales 135614|Xanthomonadales H Methyltransferase domain - - - - - - - - - - - - Methyltransf_11 k141_15966_2 478749.BRYFOR_07479 4.89e-13 71.2 COG0438@1|root,COG1216@1|root,COG2242@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,COG2242@2|Bacteria,1TPEE@1239|Firmicutes,24D9B@186801|Clostridia 186801|Clostridia H Methyltransferase domain - - - - - - - - - - - - Methyltransf_11,Methyltransf_12,Methyltransf_23,Methyltransf_25 k141_5414_1 1116375.VEJY3_01575 0.0 950.0 COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,1RMH7@1236|Gammaproteobacteria,1XUHS@135623|Vibrionales 135623|Vibrionales S transport system, fused permease components - - - - - - - - - - - - DUF3394,DctM k141_5414_2 1280001.BAOA01000021_gene813 6.02e-220 608.0 COG2358@1|root,COG2358@2|Bacteria,1MXW1@1224|Proteobacteria,1RQN1@1236|Gammaproteobacteria,1XU72@135623|Vibrionales 135623|Vibrionales S transport system periplasmic component - - - ko:K07080 - - - - ko00000 - - - NMT1_3 k141_26953_1 265729.GS18_0205940 6.07e-81 252.0 COG0247@1|root,COG0247@2|Bacteria,1TR46@1239|Firmicutes,4HAY9@91061|Bacilli,1ZATD@1386|Bacillus 91061|Bacilli C Glycolate oxidase glcF - - ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001 - - - CCG,Fer4_8 k141_2883_1 218284.CCDN010000001_gene1770 5.67e-109 325.0 28KI6@1|root,2ZA3G@2|Bacteria,1UYE9@1239|Firmicutes,4HB9Y@91061|Bacilli,1ZF3A@1386|Bacillus 91061|Bacilli S Spore germination B3/ GerAC like, C-terminal - - - - - - - - - - - - Spore_GerAC k141_2883_2 1196031.ALEG01000070_gene841 1.79e-18 85.1 COG0697@1|root,COG0697@2|Bacteria,1TSX6@1239|Firmicutes,4HCV4@91061|Bacilli,1ZCUJ@1386|Bacillus 91061|Bacilli EG Bacillus/Clostridium GerA spore germination protein - - - - - - - - - - - - GerA k141_10202_1 1116375.VEJY3_02845 3.68e-236 653.0 COG1473@1|root,COG1473@2|Bacteria,1MUIV@1224|Proteobacteria,1RQAM@1236|Gammaproteobacteria,1XVA0@135623|Vibrionales 135623|Vibrionales S COG1473 Metal-dependent amidase aminoacylase carboxypeptidase - - 3.5.1.32 ko:K01451 ko00360,map00360 - R01424 RC00096,RC00162 ko00000,ko00001,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 k141_10202_2 1116375.VEJY3_02850 3.01e-198 551.0 COG0583@1|root,COG0583@2|Bacteria,1R9GU@1224|Proteobacteria,1RQYB@1236|Gammaproteobacteria,1XW1J@135623|Vibrionales 135623|Vibrionales K Bacterial regulatory helix-turn-helix protein, lysR family - - - - - - - - - - - - HTH_1,LysR_substrate k141_32535_1 997296.PB1_05752 4.39e-48 170.0 COG2304@1|root,COG2304@2|Bacteria,1TQHE@1239|Firmicutes,4HBUG@91061|Bacilli,1ZQU2@1386|Bacillus 91061|Bacilli S von Willebrand factor (vWF) type A domain - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - VWA,VWA_2 k141_32535_2 35841.BT1A1_2822 1.44e-21 85.9 2DQ51@1|root,334SP@2|Bacteria,1VJK2@1239|Firmicutes,4HPZ4@91061|Bacilli,1ZJRW@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_7627_1 218284.CCDN010000002_gene2215 2.74e-88 263.0 2BE93@1|root,32804@2|Bacteria,1UAWI@1239|Firmicutes,4IM9C@91061|Bacilli,1ZJIH@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_8958_1 1227360.C176_13942 4.77e-31 119.0 COG0577@1|root,COG0577@2|Bacteria,1TWFZ@1239|Firmicutes,4H9RQ@91061|Bacilli,26DE8@186818|Planococcaceae 91061|Bacilli V FtsX-like permease family hrtB GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02004,ko:K09813 ko02010,map02010 M00257,M00258 - - ko00000,ko00001,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD k141_8958_2 1227360.C176_13947 2.62e-31 116.0 COG1136@1|root,COG1136@2|Bacteria,1TQP5@1239|Firmicutes,4HBXK@91061|Bacilli,26EB2@186818|Planococcaceae 91061|Bacilli V ATPases associated with a variety of cellular activities hrtA - - ko:K02003,ko:K09814 ko02010,map02010 M00257,M00258 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1 - - ABC_tran k141_6541_1 218284.CCDN010000002_gene2816 1.31e-179 506.0 COG2367@1|root,COG2367@2|Bacteria,1V2JD@1239|Firmicutes,4HGP1@91061|Bacilli,1ZD4B@1386|Bacillus 91061|Bacilli V Beta-lactamase enzyme family - - 3.4.16.4 ko:K01286 - - - - ko00000,ko01000 - - - Beta-lactamase2 k141_21950_1 218284.CCDN010000007_gene3849 4.35e-79 239.0 2CFK2@1|root,347F6@2|Bacteria,1VZDI@1239|Firmicutes,4HYUB@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - k141_11366_1 218284.CCDN010000002_gene2135 1.42e-56 194.0 COG0210@1|root,COG0210@2|Bacteria,1TPVG@1239|Firmicutes,4HBVF@91061|Bacilli,1ZCF6@1386|Bacillus 91061|Bacilli L DNA helicase yjcD - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C,YdjO k141_1666_1 218284.CCDN010000002_gene2057 8.07e-85 250.0 COG3871@1|root,COG3871@2|Bacteria,1V6MX@1239|Firmicutes,4HIYZ@91061|Bacilli,1ZH2Z@1386|Bacillus 91061|Bacilli S general stress protein ydaG - - - - - - - - - - - Putative_PNPOx,Pyrid_ox_like k141_18505_1 218284.CCDN010000007_gene3953 4.86e-135 394.0 COG1502@1|root,COG1502@2|Bacteria,1USPT@1239|Firmicutes,4HCJD@91061|Bacilli,1ZC77@1386|Bacillus 91061|Bacilli I Belongs to the phospholipase D family. Cardiolipin synthase subfamily clsB GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0032048,GO:0032049,GO:0032502,GO:0043934,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 - ko:K06131 ko00564,ko01100,map00564,map01100 - R07390 RC00017 ko00000,ko00001,ko01000 - - - PLDc_2 k141_20719_1 42565.FP66_08255 6.16e-115 342.0 COG1055@1|root,COG1055@2|Bacteria,1MUH8@1224|Proteobacteria,1RPSM@1236|Gammaproteobacteria,1XI9V@135619|Oceanospirillales 135619|Oceanospirillales P Sodium proton antiporter - - - - - - - - - - - - CitMHS k141_26954_2 218284.CCDN010000002_gene2070 6.16e-07 50.4 COG1199@1|root,COG1199@2|Bacteria,1TPNB@1239|Firmicutes,4HD6T@91061|Bacilli,1ZAUN@1386|Bacillus 91061|Bacilli KL DEAD_2 uvrB3 - 3.1.12.1 ko:K07464 - - - - ko00000,ko01000,ko02048 - - - DEAD,DEAD_2,HBB,Helicase_C_2,PDDEXK_1 k141_27742_2 1379270.AUXF01000006_gene271 3.84e-47 163.0 COG1137@1|root,COG1137@2|Bacteria,1ZT4S@142182|Gemmatimonadetes 142182|Gemmatimonadetes S ABC transporter - - - ko:K06861 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko01000,ko02000 1.B.42.1 - - ABC_tran k141_19628_1 1294265.JCM21738_3437 4.25e-156 443.0 COG4129@1|root,COG4129@2|Bacteria,1TP2T@1239|Firmicutes,4HAWV@91061|Bacilli,1ZBBI@1386|Bacillus 91061|Bacilli S Putative aromatic acid exporter C-terminal domain yqjA - - - - - - - - - - - ArAE_1,ArAE_1_C k141_6542_1 866895.HBHAL_4752 4.89e-107 320.0 COG1593@1|root,COG1593@2|Bacteria,1TPNU@1239|Firmicutes,4HCEQ@91061|Bacilli,3ND53@45667|Halobacillus 91061|Bacilli G Tripartite ATP-independent periplasmic transporter, DctM component - - - - - - - - - - - - DctM k141_29049_1 218284.CCDN010000002_gene2196 8.56e-95 282.0 COG1284@1|root,COG1284@2|Bacteria,1TR9J@1239|Firmicutes,4H9N6@91061|Bacilli,1ZC8U@1386|Bacillus 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2179) XK27_10395 - - - - - - - - - - - DUF2179,YitT_membrane k141_13816_1 218284.CCDN010000001_gene784 3.4e-60 188.0 COG2839@1|root,COG2839@2|Bacteria,1V5DQ@1239|Firmicutes,4HJSF@91061|Bacilli,1ZQR9@1386|Bacillus 91061|Bacilli S protein conserved in bacteria - - - ko:K09793 - - - - ko00000 - - - DUF456 k141_8959_1 218284.CCDN010000002_gene2943 1.3e-92 277.0 COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4HBB9@91061|Bacilli,1ZC1H@1386|Bacillus 91061|Bacilli EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components dppC - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1,OppC_N k141_8959_2 218284.CCDN010000002_gene2942 9.92e-32 118.0 COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,4HBED@91061|Bacilli,1ZBXY@1386|Bacillus 91061|Bacilli EP COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components dppB - - ko:K02033 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 k141_12631_1 218284.CCDN010000001_gene1917 5.72e-65 206.0 COG3190@1|root,COG3190@2|Bacteria,1VGFI@1239|Firmicutes,4HJJQ@91061|Bacilli,1ZETY@1386|Bacillus 91061|Bacilli N Flagellar biosynthesis protein, FliO fliZ - - ko:K02418 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - FliO k141_27743_1 545693.BMQ_0643 1.43e-11 60.5 COG1403@1|root,COG1403@2|Bacteria,1VFR5@1239|Firmicutes,4HMDC@91061|Bacilli,1ZR8A@1386|Bacillus 91061|Bacilli V COG1403 Restriction endonuclease - - - - - - - - - - - - HNH k141_24295_2 1122201.AUAZ01000001_gene2312 3.35e-47 159.0 COG0680@1|root,COG0680@2|Bacteria,1RE1C@1224|Proteobacteria,1S4H2@1236|Gammaproteobacteria,468FP@72275|Alteromonadaceae 1236|Gammaproteobacteria C Hydrogenase maturation protease hyaD - - ko:K03605 - - - - ko00000,ko01000,ko01002 - - - HycI k141_10203_1 1279017.AQYJ01000023_gene3161 1.46e-77 247.0 COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,1RNI4@1236|Gammaproteobacteria,4664Q@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1008 NADH ubiquinone oxidoreductase subunit 4 (chain M) nuoM - 1.6.5.3 ko:K00342 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_M k141_10203_2 1279017.AQYJ01000023_gene3162 4.34e-124 373.0 COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,1RNKN@1236|Gammaproteobacteria,469GC@72275|Alteromonadaceae 1236|Gammaproteobacteria CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit nuoL GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015672,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0030964,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0051179,GO:0051234,GO:0055085,GO:0070469,GO:0070470,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1902600,GO:1990204 1.6.5.3 ko:K00341 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - e_coli_core.b2278,iAF1260.b2278,iBWG_1329.BWG_2052,iECDH10B_1368.ECDH10B_2440,iECDH1ME8569_1439.ECDH1ME8569_2215,iEcDH1_1363.EcDH1_1379,iJN746.PP_4129,iJO1366.b2278,iJR904.b2278,iY75_1357.Y75_RS11945 Proton_antipo_M,Proton_antipo_N k141_17175_1 1042377.AFPJ01000037_gene2846 9.5e-13 65.9 COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,1RMT6@1236|Gammaproteobacteria,46577@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism adk GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004017,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006412,GO:0006518,GO:0006629,GO:0006644,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0010467,GO:0015949,GO:0015950,GO:0015951,GO:0016070,GO:0016208,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019205,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 - - iECH74115_1262.ECH74115_0566,iEKO11_1354.EKO11_3373,iG2583_1286.G2583_0586,iJN746.PP_1506 ADK,ADK_lid k141_17175_2 202956.BBNL01000002_gene1155 5.92e-22 93.2 COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,1RMMS@1236|Gammaproteobacteria,3NJ4U@468|Moraxellaceae 1236|Gammaproteobacteria H Catalyzes the ferrous insertion into protoporphyrin IX hemH GO:0003674,GO:0003824,GO:0004325,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009314,GO:0009416,GO:0009628,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0050896,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R00310,R11329 RC01012 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_1540,iECS88_1305.ECS88_0472,iEcE24377_1341.EcE24377A_0515 Ferrochelatase k141_706_1 218284.CCDN010000004_gene3134 9.34e-128 382.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,1ZBIW@1386|Bacillus 91061|Bacilli V COG1132 ABC-type multidrug transport system, ATPase and permease components yheH GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702 - ko:K18217,ko:K18890 ko02010,map02010 M00635,M00707 - - ko00000,ko00001,ko00002,ko01504,ko02000 3.A.1,3.A.1.106.13,3.A.1.106.5 - - ABC_membrane,ABC_tran k141_7629_1 218284.CCDN010000001_gene1946 2.53e-57 184.0 COG2968@1|root,COG2968@2|Bacteria,1VB7C@1239|Firmicutes,4HH35@91061|Bacilli,1ZGZ6@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF541) bp26 - - ko:K09807 - - - - ko00000 - - - SIMPL k141_26956_1 323850.Shew_3152 1.75e-38 147.0 COG1404@1|root,COG1404@2|Bacteria,1MVJE@1224|Proteobacteria,1RQ2M@1236|Gammaproteobacteria,2Q8GT@267890|Shewanellaceae 1236|Gammaproteobacteria O PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - - - - - - - - - - Inhibitor_I9,PA,Peptidase_S8 k141_8960_1 218284.CCDN010000002_gene2798 7.39e-186 559.0 COG0308@1|root,COG0577@1|root,COG4591@1|root,COG0308@2|Bacteria,COG0577@2|Bacteria,COG4591@2|Bacteria,1TSZH@1239|Firmicutes,4HCKC@91061|Bacilli 91061|Bacilli MV FtsX-like permease family - - - - - - - - - - - - FtsX k141_6544_1 1294265.JCM21738_3362 7.93e-147 415.0 COG0300@1|root,COG0300@2|Bacteria,1U5VD@1239|Firmicutes,4HES8@91061|Bacilli,1ZDY5@1386|Bacillus 91061|Bacilli S Enoyl-(Acyl carrier protein) reductase - - - ko:K07124 - - - - ko00000 - - - adh_short k141_18508_1 574376.BAMA_20945 1.3e-64 201.0 COG1670@1|root,COG1670@2|Bacteria,1V3BJ@1239|Firmicutes,4HGAX@91061|Bacilli,1ZGF9@1386|Bacillus 91061|Bacilli J Acetyltransferase (GNAT) domain - - 2.3.1.57 ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 M00135 R01154 RC00004,RC00096 ko00000,ko00001,ko00002,ko01000 - - - Acetyltransf_1 k141_15998_1 1294265.JCM21738_3966 9.18e-34 117.0 COG4976@1|root,COG4976@2|Bacteria 2|Bacteria O Methyltransferase cmoA - - ko:K15256 - - - - ko00000,ko01000,ko03016 - - - Methyltransf_25,NodS,PIG-L k141_15998_2 1196031.ALEG01000061_gene2135 7.42e-68 206.0 COG0799@1|root,COG0799@2|Bacteria,1VA2Z@1239|Firmicutes,4HKEJ@91061|Bacilli,1ZGYR@1386|Bacillus 91061|Bacilli J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation rsfS GO:0003674,GO:0005488,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113 - ko:K09710 - - - - ko00000,ko03009 - - - RsfS k141_15998_3 1294265.JCM21738_3968 3.74e-45 149.0 COG1713@1|root,COG1713@2|Bacteria,1V6Y1@1239|Firmicutes,4HHRY@91061|Bacilli,1ZCQJ@1386|Bacillus 91061|Bacilli H HD superfamily hydrolase involved in NAD metabolism yqeK - - - - - - - - - - - HD k141_36112_2 1285586.H131_23094 4.77e-246 681.0 COG3547@1|root,COG3547@2|Bacteria,1UY93@1239|Firmicutes,4HDTQ@91061|Bacilli,3IYGE@400634|Lysinibacillus 91061|Bacilli L Transposase - - - - - - - - - - - - DEDD_Tnp_IS110,Transposase_20 k141_5416_1 1116375.VEJY3_10105 1.26e-87 266.0 COG3489@1|root,COG3489@2|Bacteria,1MWBW@1224|Proteobacteria,1S2FI@1236|Gammaproteobacteria,1XSGX@135623|Vibrionales 135623|Vibrionales S periplasmic lipoprotein - - - ko:K07338 - - - - ko00000 - - - Peptidase_M75 k141_5416_2 1116375.VEJY3_10100 3.71e-240 662.0 COG3490@1|root,COG3490@2|Bacteria,1NNS5@1224|Proteobacteria,1S3YB@1236|Gammaproteobacteria,1XTIA@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria - - - ko:K09947 - - - - ko00000 - - - DUF1513 k141_5416_3 223926.28806908 5.4e-63 207.0 COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,1RQR7@1236|Gammaproteobacteria,1XUQ4@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria VP1916 - - ko:K21470 - - - - ko00000,ko01002,ko01011 - - - PG_binding_1,YkuD k141_13820_1 1198452.Jab_2c04250 1.99e-23 103.0 COG2871@1|root,COG3182@1|root,COG2871@2|Bacteria,COG3182@2|Bacteria,1QTUV@1224|Proteobacteria,2VNTV@28216|Betaproteobacteria,476DV@75682|Oxalobacteraceae 28216|Betaproteobacteria C Oxidoreductase NAD-binding domain nqrF - 1.6.5.8 ko:K00351 - - - - ko00000,ko01000 - - - FAD_binding_6,Fer2,NAD_binding_1 k141_11371_1 1294265.JCM21738_3522 4.08e-134 383.0 COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,4HA1D@91061|Bacilli,1ZM4T@1386|Bacillus 91061|Bacilli L Ligase N family ligA GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - - BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5 k141_19629_1 1279017.AQYJ01000025_gene760 1.12e-07 52.4 COG2304@1|root,COG2304@2|Bacteria,1MXQ7@1224|Proteobacteria,1RMDX@1236|Gammaproteobacteria,464NT@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein containing a von Willebrand factor type A (vWA) domain - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - VWA k141_19629_2 765910.MARPU_09915 9.87e-13 70.5 COG2304@1|root,COG2304@2|Bacteria,1QVQA@1224|Proteobacteria,1S9W8@1236|Gammaproteobacteria,1WYQH@135613|Chromatiales 135613|Chromatiales S Domain of unknown function (DUF4381) - - - - - - - - - - - - DUF4381 k141_19629_3 1279017.AQYJ01000025_gene758 3e-153 438.0 COG1721@1|root,COG1721@2|Bacteria,1Q7RR@1224|Proteobacteria,1RNNP@1236|Gammaproteobacteria,466HG@72275|Alteromonadaceae 1236|Gammaproteobacteria S conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - - - - - - - - - - DUF58 k141_18509_1 218284.CCDN010000006_gene3768 5.8e-87 266.0 COG4191@1|root,COG4191@2|Bacteria,1TRYP@1239|Firmicutes,4HE85@91061|Bacilli,1ZBXM@1386|Bacillus 91061|Bacilli T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,HisK_N k141_8961_2 1042377.AFPJ01000007_gene1891 5.49e-39 137.0 COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,1RMWK@1236|Gammaproteobacteria,466E9@72275|Alteromonadaceae 1236|Gammaproteobacteria V Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner lolD GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0015399,GO:0015405,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051234,GO:0051641,GO:0055085,GO:0070727,GO:0071944,GO:0072657,GO:0089705,GO:0097159,GO:0097367,GO:0098796,GO:0098797,GO:1901265,GO:1901363,GO:1990778 - ko:K09810 ko02010,map02010 M00255 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.125 - - ABC_tran k141_10228_1 1397528.Q671_08680 2.93e-114 335.0 COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,1RNMX@1236|Gammaproteobacteria,1XHRU@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde argC - 1.2.1.38 ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R03443 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC k141_35095_1 218284.CCDN010000001_gene1900 1.09e-15 73.9 COG0528@1|root,COG0528@2|Bacteria,1TPXN@1239|Firmicutes,4H9UB@91061|Bacilli,1ZBMW@1386|Bacillus 91061|Bacilli F Catalyzes the reversible phosphorylation of UMP to UDP pyrH - 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 - R00158 RC00002 ko00000,ko00001,ko01000 - - iSB619.SA_RS06240 AA_kinase k141_35095_2 218284.CCDN010000001_gene1899 2.42e-110 319.0 COG0233@1|root,COG0233@2|Bacteria,1V1F2@1239|Firmicutes,4HFSH@91061|Bacilli,1ZAZF@1386|Bacillus 91061|Bacilli J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another frr GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - ko:K02838 - - - - ko00000,ko03012 - - - RRF k141_8980_1 1279017.AQYJ01000027_gene1619 3.08e-96 286.0 COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,1RNPM@1236|Gammaproteobacteria,466EB@72275|Alteromonadaceae 1236|Gammaproteobacteria S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis yggS - - ko:K06997 - - - - ko00000 - - - Ala_racemase_N k141_6562_1 218284.CCDN010000001_gene1531 6.39e-122 363.0 COG0578@1|root,COG0578@2|Bacteria,1TQJN@1239|Firmicutes,4HAG8@91061|Bacilli,1ZCGN@1386|Bacillus 91061|Bacilli C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family glpD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.1.3.21,1.1.5.3 ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 - R00846,R00848 RC00029 ko00000,ko00001,ko01000 - - - DAO,DAO_C k141_1686_1 1453501.JELR01000002_gene426 5.39e-95 283.0 COG3836@1|root,COG3836@2|Bacteria,1MUSG@1224|Proteobacteria,1RMWJ@1236|Gammaproteobacteria,468SR@72275|Alteromonadaceae 1236|Gammaproteobacteria G Belongs to the HpcH HpaI aldolase family - - 4.1.2.52 ko:K02510 ko00350,ko01120,map00350,map01120 - R01645,R01647 RC00307,RC00572,RC00574,RC03057 ko00000,ko00001,ko01000 - - - HpcH_HpaI k141_21966_2 1453501.JELR01000002_gene1412 3.43e-44 154.0 COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,1RNS6@1236|Gammaproteobacteria,4655Y@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide bioF GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.47 ko:K00652 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R03210,R10124 RC00004,RC00039,RC02725 ko00000,ko00001,ko00002,ko01000,ko01007 - - iEC55989_1330.EC55989_0819,iECO111_1330.ECO111_0837,iECO26_1355.ECO26_0902,iSDY_1059.SDY_0830 Aminotran_1_2 k141_25662_1 525378.HMPREF0793_2232 3.55e-31 110.0 COG1141@1|root,COG1141@2|Bacteria,1VAC2@1239|Firmicutes,4HKG7@91061|Bacilli,4GZPA@90964|Staphylococcaceae 91061|Bacilli C Ferredoxin fer - - ko:K05337 - - - - ko00000 - - - Fer4_13 k141_25662_2 1499685.CCFJ01000045_gene2744 1.07e-54 182.0 COG0492@1|root,COG0492@2|Bacteria,1TRPN@1239|Firmicutes,4H9V7@91061|Bacilli,1ZCEZ@1386|Bacillus 91061|Bacilli C reductase yumC - 1.18.1.2,1.19.1.1 ko:K21567 - - - - ko00000,ko01000 - - iYO844.BSU32110 Pyr_redox_2 k141_16017_1 1042377.AFPJ01000043_gene954 6.75e-104 313.0 COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,1RMWU@1236|Gammaproteobacteria,4658B@72275|Alteromonadaceae 1236|Gammaproteobacteria M Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation surA GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006457,GO:0006458,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0022607,GO:0030288,GO:0030313,GO:0031647,GO:0031975,GO:0033218,GO:0036211,GO:0042277,GO:0042597,GO:0043163,GO:0043165,GO:0043170,GO:0043412,GO:0044085,GO:0044091,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0044764,GO:0045229,GO:0050821,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0060274,GO:0061024,GO:0061077,GO:0065007,GO:0065008,GO:0071704,GO:0071709,GO:0071840,GO:0140096,GO:1901564 5.2.1.8 ko:K03771 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_3,SurA_N k141_10230_1 42565.FP66_04230 1.75e-136 390.0 COG1732@1|root,COG1732@2|Bacteria,1MV9N@1224|Proteobacteria,1RPSP@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Glycine betaine opuCC - - ko:K05845 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - OpuAC k141_32536_1 945543.VIBR0546_10889 2.5e-182 516.0 COG1749@1|root,COG1749@2|Bacteria,1MU5J@1224|Proteobacteria,1RMWX@1236|Gammaproteobacteria,1XV3D@135623|Vibrionales 135623|Vibrionales N Flagellar hook protein FlgE flgE - - ko:K02390 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FlaE,Flg_bb_rod,Flg_bbr_C k141_32536_2 945543.VIBR0546_10894 1.87e-118 343.0 COG1843@1|root,COG1843@2|Bacteria,1R4QI@1224|Proteobacteria,1RRRM@1236|Gammaproteobacteria,1XTYI@135623|Vibrionales 135623|Vibrionales N Required for flagellar hook formation. May act as a scaffolding protein flgD - - ko:K02389 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FLgD_tudor,FlgD,FlgD_ig k141_32536_3 945543.VIBR0546_10899 2.55e-83 248.0 COG1558@1|root,COG1558@2|Bacteria,1RJB8@1224|Proteobacteria,1S8B7@1236|Gammaproteobacteria,1XWWM@135623|Vibrionales 135623|Vibrionales N Belongs to the flagella basal body rod proteins family - - - ko:K02388 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C k141_32536_4 223926.28808402 3.07e-62 192.0 COG1815@1|root,COG1815@2|Bacteria,1MZ8P@1224|Proteobacteria,1S9DS@1236|Gammaproteobacteria,1XXCT@135623|Vibrionales 135623|Vibrionales N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body - - - ko:K02387 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod k141_32536_5 675814.VIC_004760 7.71e-84 256.0 COG1261@1|root,COG1261@2|Bacteria,1N1SA@1224|Proteobacteria,1S8SQ@1236|Gammaproteobacteria,1XX1B@135623|Vibrionales 135623|Vibrionales N Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly - - - ko:K02386 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - ChapFlgA k141_32536_6 1280001.BAOA01000050_gene1435 9.07e-34 119.0 COG2747@1|root,COG2747@2|Bacteria,1NGZ4@1224|Proteobacteria,1SGER@1236|Gammaproteobacteria,1XYMB@135623|Vibrionales 135623|Vibrionales N COG2747 Negative regulator of flagellin synthesis (anti-sigma28 factor) - - - ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 - - - ko00000,ko00001,ko02035 - - - FlgM k141_32536_7 223926.28808399 1.16e-47 157.0 2C59R@1|root,337DD@2|Bacteria,1NCBH@1224|Proteobacteria,1SD85@1236|Gammaproteobacteria,1XYHN@135623|Vibrionales 135623|Vibrionales S FlgN protein - - - ko:K02399 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FlgN k141_32536_8 1219065.VPR01S_03_01660 6.76e-77 238.0 COG0741@1|root,COG0741@2|Bacteria,1N30Z@1224|Proteobacteria,1SA9P@1236|Gammaproteobacteria,1XWHM@135623|Vibrionales 135623|Vibrionales M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - - - - - - - - - - SLT k141_32536_10 1116375.VEJY3_23566 7.02e-82 243.0 COG3783@1|root,COG3783@2|Bacteria,1N8JG@1224|Proteobacteria,1SD88@1236|Gammaproteobacteria,1XXVF@135623|Vibrionales 135623|Vibrionales C COG3783 Soluble cytochrome b562 - - - ko:K15536 - - - - ko00000 - - - Cytochrom_B562 k141_32536_11 1116375.VEJY3_23571 4.74e-163 458.0 COG1387@1|root,COG1387@2|Bacteria,1MYXV@1224|Proteobacteria,1RRE9@1236|Gammaproteobacteria,1XTMG@135623|Vibrionales 135623|Vibrionales E Histidinol phosphatase and related hydrolases of the PHP family - - - ko:K04477 - - - - ko00000 - - - PHP k141_32536_12 1116375.VEJY3_23576 2.85e-172 489.0 COG5640@1|root,COG5640@2|Bacteria,1NCJ3@1224|Proteobacteria,1SFA0@1236|Gammaproteobacteria,1Y2G4@135623|Vibrionales 135623|Vibrionales M Trypsin-like serine protease - - 3.4.21.71 ko:K01346 ko04972,ko04974,map04972,map04974 - - - ko00000,ko00001,ko01000,ko01002 - - - Trypsin k141_32536_13 1116375.VEJY3_23581 8.66e-43 141.0 2AWGY@1|root,31NDD@2|Bacteria,1QK4I@1224|Proteobacteria,1TI7G@1236|Gammaproteobacteria,1XYJN@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_32536_14 223926.28809975 6.46e-85 253.0 COG1670@1|root,COG1670@2|Bacteria,1N1AF@1224|Proteobacteria,1T25C@1236|Gammaproteobacteria,1XXCY@135623|Vibrionales 135623|Vibrionales J Acetyltransferase (GNAT) domain VPA1573 - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10 k141_32536_15 1116375.VEJY3_23586 7.34e-152 432.0 COG0697@1|root,COG0697@2|Bacteria,1MXJ6@1224|Proteobacteria,1RSIB@1236|Gammaproteobacteria,1XWGN@135623|Vibrionales 135623|Vibrionales EG of the drug metabolite transporter (DMT) superfamily - - - - - - - - - - - - EamA k141_5636_3 1120953.AUBH01000010_gene73 0.0 957.0 COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,1RN0R@1236|Gammaproteobacteria,4640T@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family actP - - ko:K14393 - - - - ko00000,ko02000 2.A.21.7 - - SSF k141_19781_1 42565.FP66_01555 1.96e-169 487.0 COG3519@1|root,COG3519@2|Bacteria,1MUY4@1224|Proteobacteria,1RPK4@1236|Gammaproteobacteria,1XJ12@135619|Oceanospirillales 135619|Oceanospirillales S Type VI secretion - - - ko:K11896 - M00334 - - ko00000,ko00002,ko02044 3.A.23.1 - - T6SS_TssF k141_859_2 218284.CCDN010000001_gene649 1.11e-128 367.0 COG0632@1|root,COG0632@2|Bacteria,1V3KF@1239|Firmicutes,4HHI5@91061|Bacilli,1ZBJT@1386|Bacillus 91061|Bacilli L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB ruvA - 3.6.4.12 ko:K03550 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - HHH_5,RuvA_C,RuvA_N k141_18745_1 218284.CCDN010000001_gene783 9.79e-112 335.0 COG1283@1|root,COG1283@2|Bacteria,1TP4K@1239|Firmicutes,4HAZ0@91061|Bacilli,1ZBHZ@1386|Bacillus 91061|Bacilli P COG1283 Na phosphate symporter yjbB - - ko:K03324 - - - - ko00000,ko02000 2.A.58.2 - - Na_Pi_cotrans,PhoU k141_18745_2 1196031.ALEG01000020_gene3033 1.57e-55 177.0 COG2839@1|root,COG2839@2|Bacteria,1V5DQ@1239|Firmicutes,4HJSF@91061|Bacilli,1ZQR9@1386|Bacillus 91061|Bacilli S protein conserved in bacteria - - - ko:K09793 - - - - ko00000 - - - DUF456 k141_12811_2 1279017.AQYJ01000024_gene952 1.18e-104 310.0 COG1028@1|root,COG1028@2|Bacteria,1RAEZ@1224|Proteobacteria,1S615@1236|Gammaproteobacteria,467FQ@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - - - - - - - - - - adh_short k141_12811_3 1279017.AQYJ01000024_gene951 0.0 974.0 COG1982@1|root,COG1982@2|Bacteria,1MWK4@1224|Proteobacteria,1RMVF@1236|Gammaproteobacteria,464W7@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG1982 Arginine lysine ornithine decarboxylases - - 4.1.1.19 ko:K01584,ko:K01585 ko00330,ko01100,map00330,map01100 M00133 R00566 RC00299 ko00000,ko00001,ko00002,ko01000 - - - OKR_DC_1,OKR_DC_1_C k141_27902_1 1347087.CBYO010000020_gene3015 1.52e-141 407.0 COG1595@1|root,COG1595@2|Bacteria,1VPR2@1239|Firmicutes 1239|Firmicutes K DNA-templated transcription, initiation - - - - - - - - - - - - - k141_14926_1 1395513.P343_14925 2.52e-24 101.0 29H5Q@1|root,31K0D@2|Bacteria,1V94V@1239|Firmicutes,4HK2Z@91061|Bacilli 91061|Bacilli S Nuclease-related domain - - - - - - - - - - - - NERD k141_32716_1 1453501.JELR01000002_gene849 8.96e-132 398.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MV8W@1224|Proteobacteria,1RMQA@1236|Gammaproteobacteria,46619@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec k141_32716_2 1453501.JELR01000002_gene850 6.86e-19 85.5 COG5434@1|root,COG5434@2|Bacteria,1MXP8@1224|Proteobacteria,1RRJZ@1236|Gammaproteobacteria,4644J@72275|Alteromonadaceae 1236|Gammaproteobacteria G Belongs to the glycosyl hydrolase 28 family - - - - - - - - - - - - Glyco_hydro_28,Pectate_lyase_3 k141_31427_1 1144305.PMI02_04518 6.32e-188 542.0 COG3515@1|root,COG3515@2|Bacteria,1NRMK@1224|Proteobacteria 1224|Proteobacteria S Protein conserved in bacteria - - - - - - - - - - - - - k141_31427_2 768671.ThimaDRAFT_2134 8.19e-82 266.0 COG0668@1|root,COG0668@2|Bacteria,1MXD2@1224|Proteobacteria,1RNUB@1236|Gammaproteobacteria,1WXY4@135613|Chromatiales 135613|Chromatiales M PFAM Mechanosensitive ion channel - - - - - - - - - - - - MS_channel k141_9157_1 218284.CCDN010000002_gene2730 1.14e-78 251.0 COG2213@1|root,COG4668@1|root,COG2213@2|Bacteria,COG4668@2|Bacteria,1TPE3@1239|Firmicutes,4HAVV@91061|Bacilli,1ZC81@1386|Bacillus 91061|Bacilli G COG2213 Phosphotransferase system, mannitol-specific IIBC component mtlA - 2.7.1.197 ko:K02798,ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 M00274 R02704 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1.12,4.A.2.1.2,4.A.2.1.24,4.A.2.1.5 - - PTS_EIIA_2,PTS_EIIC,PTS_IIB k141_20855_1 1294265.JCM21738_3777 1.49e-116 340.0 COG0642@1|root,COG2205@2|Bacteria,1UPFH@1239|Firmicutes,4IV44@91061|Bacilli,1ZG3M@1386|Bacillus 91061|Bacilli T Membrane-associated sensor domain - - - - - - - - - - - - MASE3 k141_5637_1 586416.GZ22_14660 1.16e-48 169.0 COG2309@1|root,COG2309@2|Bacteria,1TP65@1239|Firmicutes,4H9W8@91061|Bacilli 91061|Bacilli E COG2309 Leucyl aminopeptidase (aminopeptidase T) - - - ko:K19689 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M29 k141_1818_1 945713.IALB_2360 2.43e-27 110.0 COG3342@1|root,COG3342@2|Bacteria 2|Bacteria S Family of unknown function (DUF1028) - - - - - - - - - - - - DUF1028,TPR_16,TPR_19 k141_11577_1 1453501.JELR01000002_gene943 8.85e-191 537.0 COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,1RN4I@1236|Gammaproteobacteria,46412@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) aroB GO:0000166,GO:0003674,GO:0003824,GO:0003856,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0051287,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.4 ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03083 RC00847 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b3389,iBWG_1329.BWG_3080,iECDH10B_1368.ECDH10B_3564,iECDH1ME8569_1439.ECDH1ME8569_3268,iECNA114_1301.ECNA114_3486,iEcDH1_1363.EcDH1_0324,iJO1366.b3389,iJR904.b3389,iY75_1357.Y75_RS20275 DHQ_synthase k141_7803_1 935836.JAEL01000079_gene120 1.09e-12 64.7 COG1863@1|root,COG1863@2|Bacteria,1V52M@1239|Firmicutes,4HI4G@91061|Bacilli,1ZGAK@1386|Bacillus 91061|Bacilli P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali mrpE - - ko:K05569 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - MNHE k141_7803_3 218284.CCDN010000005_gene3442 4.17e-53 169.0 COG1320@1|root,COG1320@2|Bacteria,1VABT@1239|Firmicutes,4HKX5@91061|Bacilli,1ZHVK@1386|Bacillus 91061|Bacilli P COG1320 Multisubunit Na H antiporter, MnhG subunit mrpG - - ko:K05571 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - iYO844.BSU31660 PhaG_MnhG_YufB k141_30278_1 218284.CCDN010000007_gene3870 5.85e-11 62.0 2E2NT@1|root,32XRT@2|Bacteria,1VEBQ@1239|Firmicutes,4HKGD@91061|Bacilli,1ZHTE@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_30278_2 406124.ACPC01000019_gene2924 9.65e-41 135.0 arCOG03092@1|root,32YMQ@2|Bacteria,1VBQ7@1239|Firmicutes,4HKSP@91061|Bacilli,1ZHUX@1386|Bacillus 91061|Bacilli S Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth. GvpA type proteins form the essential core of the structure gvpA - - - - - - - - - - - Gas_vesicle k141_3018_2 1453501.JELR01000002_gene1011 2.27e-309 854.0 COG3540@1|root,COG3540@2|Bacteria,1MWAF@1224|Proteobacteria,1RNY4@1236|Gammaproteobacteria,464EY@72275|Alteromonadaceae 1236|Gammaproteobacteria P alkaline phosphatase phoD - 3.1.3.1 ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 M00126 R04620 RC00017 ko00000,ko00001,ko00002,ko01000 - - - PhoD,PhoD_N k141_3018_3 1279017.AQYJ01000027_gene1695 7.03e-18 88.6 COG4642@1|root,COG4642@2|Bacteria,1P07C@1224|Proteobacteria,1S26V@1236|Gammaproteobacteria,4682N@72275|Alteromonadaceae 1236|Gammaproteobacteria S Peptidase C13 family - - - - - - - - - - - - MORN,Peptidase_C13 k141_16168_1 218284.CCDN010000001_gene1014 6.25e-77 239.0 COG0491@1|root,COG0491@2|Bacteria,1TQPX@1239|Firmicutes,4HAV6@91061|Bacilli,1ZCFS@1386|Bacillus 91061|Bacilli S COG0491 Zn-dependent hydrolases, including glyoxylases yqjP - - - - - - - - - - - Lactamase_B k141_16168_2 1132442.KB889752_gene2162 7.7e-67 214.0 COG0345@1|root,COG0345@2|Bacteria,1TP1E@1239|Firmicutes,4H9RV@91061|Bacilli,1ZCWZ@1386|Bacillus 91061|Bacilli E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline proC - 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 - - - F420_oxidored,P5CR_dimer k141_36240_1 1294265.JCM21738_490 4.84e-126 377.0 COG1033@1|root,COG1033@2|Bacteria,1VSWA@1239|Firmicutes,4HBIV@91061|Bacilli 91061|Bacilli S MMPL family ydfJ - - ko:K07003 - - - - ko00000 - - - MMPL k141_18747_1 1279017.AQYJ01000022_gene2684 2.9e-83 251.0 COG3764@1|root,COG3764@2|Bacteria,1P806@1224|Proteobacteria,1S9RI@1236|Gammaproteobacteria,467ZM@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG3764 Sortase (surface protein transpeptidase) srtA - 3.4.22.70 ko:K07284 - - - - ko00000,ko01000,ko01002,ko01011 - - - Sortase k141_7804_1 665959.HMPREF1013_01111 9.9e-77 248.0 COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4HBBB@91061|Bacilli,1ZCKA@1386|Bacillus 91061|Bacilli M Penicillin-binding Protein pbpD - 2.4.1.129,3.4.16.4 ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase k141_27173_1 439497.RR11_649 2.26e-17 85.5 COG3307@1|root,COG3307@2|Bacteria,1MV4S@1224|Proteobacteria,2TV8W@28211|Alphaproteobacteria,4NAYM@97050|Ruegeria 28211|Alphaproteobacteria M O-antigen ligase like membrane protein - - - - - - - - - - - - - k141_27173_2 1286106.MPL1_00175 2.79e-95 299.0 COG0438@1|root,COG0438@2|Bacteria,1MVKK@1224|Proteobacteria,1RQ8J@1236|Gammaproteobacteria,463NS@72273|Thiotrichales 72273|Thiotrichales M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 k141_27173_3 582899.Hden_1346 1.2e-130 382.0 COG1215@1|root,COG1215@2|Bacteria,1R4ZM@1224|Proteobacteria,2U479@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 k141_27173_4 1301098.PKB_1187 3.74e-52 177.0 COG1922@1|root,COG1922@2|Bacteria,1N1HD@1224|Proteobacteria,1RP6P@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA (Lipid II), the second lipid-linked intermediate involved in enterobacterial common antigen (ECA) synthesis - - 2.4.1.187 ko:K05946 ko05111,map05111 - - - ko00000,ko00001,ko01000,ko01003 - GT26 - CoA_binding_3,Glyco_tran_WecB,STAS_2 k141_27173_5 388739.RSK20926_05102 5.04e-56 188.0 COG1215@1|root,COG1215@2|Bacteria,1QUG1@1224|Proteobacteria,2TWJ1@28211|Alphaproteobacteria,2P1K4@2433|Roseobacter 28211|Alphaproteobacteria M COG0463 Glycosyltransferases involved in cell wall biogenesis - - - - - - - - - - - - Glyco_trans_2_3,Glycos_transf_2 k141_5638_2 1280001.BAOA01000058_gene4606 1.98e-46 150.0 2EYVM@1|root,33S2Q@2|Bacteria,1NQRG@1224|Proteobacteria,1SK3Y@1236|Gammaproteobacteria,1XXAV@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_37466_2 1116375.VEJY3_02840 4.75e-88 271.0 COG0477@1|root,COG2814@2|Bacteria,1QTW0@1224|Proteobacteria 1224|Proteobacteria EGP Major Facilitator proP - - ko:K03762,ko:K08195 - - - - ko00000,ko02000 2.A.1.15,2.A.1.6.4 - iJN746.PP_2703 MFS_1,Sugar_tr k141_4288_1 1492922.GY26_08460 2.74e-114 340.0 COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,1RQX2@1236|Gammaproteobacteria,1J801@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C FAD linked oxidases, C-terminal domain - - 1.1.2.4 ko:K00102 ko00620,map00620 - R00197 RC00044 ko00000,ko00001,ko01000 - - - FAD-oxidase_C,FAD_binding_4 k141_23462_1 218284.CCDN010000001_gene605 6.82e-96 290.0 COG0001@1|root,COG0001@2|Bacteria,1TPNH@1239|Firmicutes,4HANQ@91061|Bacilli,1ZBUT@1386|Bacillus 91061|Bacilli H Glutamate-1-semialdehyde aminotransferase hemL - 5.4.3.8 ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02272 RC00677 ko00000,ko00001,ko00002,ko01000,ko01007 - - iSB619.SA_RS08395 Aminotran_3 k141_35291_1 1116375.VEJY3_10580 1.02e-57 184.0 COG4544@1|root,COG4544@2|Bacteria,1MZQU@1224|Proteobacteria,1S9RP@1236|Gammaproteobacteria,1XV15@135623|Vibrionales 135623|Vibrionales S COG0468 RecA RadA recombinase - - - - - - - - - - - - RecA k141_35291_2 1116375.VEJY3_10575 2.68e-170 476.0 COG1028@1|root,COG1028@2|Bacteria,1MWBC@1224|Proteobacteria,1RNNV@1236|Gammaproteobacteria,1XSBP@135623|Vibrionales 135623|Vibrionales IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) yciK - - - - - - - - - - - adh_short k141_35291_3 1116375.VEJY3_10570 1.88e-218 607.0 COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,1RNN9@1236|Gammaproteobacteria,1XTZB@135623|Vibrionales 135623|Vibrionales OU COG0616 Periplasmic serine proteases (ClpP class) sohB - - ko:K04774 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S49,Peptidase_S49_N k141_35291_4 223926.28807024 1.73e-146 414.0 COG0283@1|root,COG0283@2|Bacteria,1MUUD@1224|Proteobacteria,1RNKT@1236|Gammaproteobacteria,1XSRV@135623|Vibrionales 135623|Vibrionales F Belongs to the cytidylate kinase family. Type 1 subfamily cmk GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0015949,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 ko:K00945 ko00240,ko01100,map00240,map01100 M00052 R00158,R00512,R01665 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Cytidylate_kin k141_35291_5 223926.28807023 0.0 1033.0 COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,1RMFY@1236|Gammaproteobacteria,1XSTZ@135623|Vibrionales 135623|Vibrionales J thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence rpsA - - ko:K02945 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - S1 k141_35291_6 1280001.BAOA01000086_gene3537 5.68e-61 187.0 COG0776@1|root,COG0776@2|Bacteria,1MZ7M@1224|Proteobacteria,1S8XZ@1236|Gammaproteobacteria,1XXU9@135623|Vibrionales 135623|Vibrionales K This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control himD GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009889,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2001141 - ko:K05788 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding k141_35291_7 223926.28807021 2.86e-44 145.0 COG3771@1|root,COG3771@2|Bacteria,1MZGX@1224|Proteobacteria,1S9X9@1236|Gammaproteobacteria,1XYIY@135623|Vibrionales 135623|Vibrionales S Involved in the assembly of lipopolysaccharide (LPS) lapA - - ko:K08992 - - - - ko00000 - - - LapA_dom k141_35291_8 1219076.N646_1102 1.14e-277 759.0 COG2956@1|root,COG2956@2|Bacteria,1MVDP@1224|Proteobacteria,1RP29@1236|Gammaproteobacteria,1XU1S@135623|Vibrionales 135623|Vibrionales G Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane lapB - - ko:K19804 - - - - ko00000 - - - TPR_16,TPR_19,TPR_7,TPR_8 k141_35291_9 223926.28807019 3.65e-156 439.0 COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,1RNJR@1236|Gammaproteobacteria,1XUKK@135623|Vibrionales 135623|Vibrionales F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) pyrF GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 ko:K01591 ko00240,ko01100,map00240,map01100 M00051 R00965 RC00409 ko00000,ko00001,ko00002,ko01000 - - - OMPdecase k141_35291_10 1116375.VEJY3_10535 0.0 1214.0 COG4166@1|root,COG4166@2|Bacteria,1MUVU@1224|Proteobacteria,1RMA1@1236|Gammaproteobacteria,1XUMM@135623|Vibrionales 135623|Vibrionales E ABC-type oligopeptide transport system, periplasmic component - - - ko:K13893 ko02010,map02010 M00349 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.21,3.A.1.5.24 - - SBP_bac_5 k141_35291_11 223926.28807017 5.88e-36 123.0 2B4R4@1|root,31XHF@2|Bacteria,1QK4Q@1224|Proteobacteria,1TI7R@1236|Gammaproteobacteria,1XYKJ@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_35291_12 1116375.VEJY3_10520 1.46e-160 451.0 COG0463@1|root,COG0463@2|Bacteria,1MW2G@1224|Proteobacteria,1S22P@1236|Gammaproteobacteria,1XUUW@135623|Vibrionales 135623|Vibrionales M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 k141_35291_13 1116375.VEJY3_10515 1.03e-136 389.0 COG0398@1|root,COG0398@2|Bacteria,1RDYV@1224|Proteobacteria,1SA20@1236|Gammaproteobacteria,1XWTJ@135623|Vibrionales 135623|Vibrionales S SNARE associated Golgi protein - - - - - - - - - - - - SNARE_assoc k141_35291_14 1116375.VEJY3_10510 0.0 1038.0 COG1807@1|root,COG1807@2|Bacteria,1MXH5@1224|Proteobacteria,1RSQE@1236|Gammaproteobacteria,1XVGX@135623|Vibrionales 135623|Vibrionales M Dolichyl-phosphate-mannose-protein mannosyltransferase - - - - - - - - - - - - PMT_2 k141_35291_15 1056512.D515_01428 1.81e-40 141.0 COG3009@1|root,COG3009@2|Bacteria,1PJIN@1224|Proteobacteria,1RQTB@1236|Gammaproteobacteria,1XSBN@135623|Vibrionales 135623|Vibrionales S ABC-type transport auxiliary lipoprotein component - - - ko:K09857 - - - - ko00000 - - - ABC_trans_aux k141_35291_16 1116375.VEJY3_10500 6.21e-304 839.0 COG1463@1|root,COG3008@1|root,COG1463@2|Bacteria,COG3008@2|Bacteria,1MU1T@1224|Proteobacteria,1RN89@1236|Gammaproteobacteria,1XSDG@135623|Vibrionales 135623|Vibrionales Q MlaD protein pqiB - - ko:K06192 - - - - ko00000 - - - MlaD k141_35291_17 223926.28807010 4.94e-277 762.0 COG2995@1|root,COG2995@2|Bacteria,1MWG1@1224|Proteobacteria,1RM9Z@1236|Gammaproteobacteria,1XTZG@135623|Vibrionales 135623|Vibrionales S Paraquat-inducible protein A pqiA - - ko:K03808 - - - - ko00000 - - - PqiA k141_35291_18 1116375.VEJY3_10490 1.06e-236 652.0 COG3258@1|root,COG3258@2|Bacteria,1NIQK@1224|Proteobacteria,1RZH1@1236|Gammaproteobacteria,1XV8G@135623|Vibrionales 135623|Vibrionales C Cytochrome C oxidase, cbb3-type, subunit III - - 1.8.2.2 ko:K19713 - - - - ko00000,ko01000 - - - Cytochrom_C,Cytochrome_CBB3 k141_35291_19 1219076.N646_1093 4.82e-128 365.0 COG2863@1|root,COG2863@2|Bacteria,1RGTS@1224|Proteobacteria,1S6Z3@1236|Gammaproteobacteria,1Y2MG@135623|Vibrionales 135623|Vibrionales C Cytochrome c - - - - - - - - - - - - Cytochrom_C k141_35291_20 223926.28807007 0.0 1956.0 COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,1RQK9@1236|Gammaproteobacteria,1XUGH@135623|Vibrionales 135623|Vibrionales C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - ko:K08357 ko00920,ko01120,ko02020,map00920,map01120,map02020 - R10150 RC03109 ko00000,ko00001,ko02000 5.A.3.10 - - Molybdopterin,Molydop_binding k141_35291_21 1219076.N646_1091 1.04e-215 602.0 COG3301@1|root,COG3301@2|Bacteria,1QU9J@1224|Proteobacteria,1T1VQ@1236|Gammaproteobacteria,1XT3N@135623|Vibrionales 135623|Vibrionales P Polysulphide reductase, NrfD VP2013 - - ko:K08359 ko00920,ko01120,ko02020,map00920,map01120,map02020 - R10150 RC03109 ko00000,ko00001,ko02000 5.A.3.10 - - NrfD k141_3046_2 1453501.JELR01000001_gene3013 5.52e-64 201.0 COG2976@1|root,COG2976@2|Bacteria,1N117@1224|Proteobacteria,1S95P@1236|Gammaproteobacteria,467Y0@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria yfgM GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0009897,GO:0009986,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031233,GO:0044425,GO:0044459,GO:0044464,GO:0071575,GO:0071944,GO:0098552 - - - - - - - - - - TPR_21 k141_7837_1 863365.XHC_2083 3.93e-18 90.9 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MV8W@1224|Proteobacteria,1RMQA@1236|Gammaproteobacteria,1X5K7@135614|Xanthomonadales 135614|Xanthomonadales P receptor - - - - - - - - - - - - Plug,TonB_dep_Rec k141_18771_1 218284.CCDN010000002_gene2243 5.21e-87 269.0 COG0477@1|root,COG2814@2|Bacteria,1TQ5B@1239|Firmicutes,4HCD8@91061|Bacilli,1ZBCU@1386|Bacillus 91061|Bacilli EGP Transmembrane secretion effector - - - - - - - - - - - - MFS_1 k141_11615_1 240302.BN982_03285 1.6e-158 461.0 COG1574@1|root,COG1574@2|Bacteria,1TQ6G@1239|Firmicutes,4HC54@91061|Bacilli,3NDTX@45667|Halobacillus 91061|Bacilli S Amidohydrolase family - - - - - - - - - - - - Amidohydro_3 k141_16193_1 929703.KE386491_gene66 5.78e-06 54.3 COG1680@1|root,COG1680@2|Bacteria,4NI1Z@976|Bacteroidetes,47NS8@768503|Cytophagia 976|Bacteroidetes V COGs COG1680 Beta-lactamase class C and other penicillin binding protein - - - - - - - - - - - - Beta-lactamase k141_32746_1 1453501.JELR01000002_gene61 1.61e-41 147.0 2DMUF@1|root,32TR1@2|Bacteria,1N2MT@1224|Proteobacteria,1SAHW@1236|Gammaproteobacteria,46C2D@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_32746_2 1453501.JELR01000002_gene62 2.28e-42 142.0 COG1695@1|root,COG1695@2|Bacteria,1N3KH@1224|Proteobacteria,1SAGS@1236|Gammaproteobacteria,4698W@72275|Alteromonadaceae 1236|Gammaproteobacteria K Transcriptional regulators - - - ko:K10947 - - - - ko00000,ko03000 - - - PadR k141_22174_1 1131730.BAVI_12499 6.17e-32 122.0 COG0531@1|root,COG0531@2|Bacteria,1UIWG@1239|Firmicutes,4ISUQ@91061|Bacilli,1ZS6D@1386|Bacillus 91061|Bacilli E Spore germination protein - - - - - - - - - - - - Spore_permease k141_19819_1 1042377.AFPJ01000015_gene1616 1.18e-79 244.0 COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,1RMBB@1236|Gammaproteobacteria,46560@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 k141_30299_2 1089545.KB913037_gene8467 5.45e-25 102.0 COG1757@1|root,COG1757@2|Bacteria,2I8CQ@201174|Actinobacteria 201174|Actinobacteria C Na H antiporter nhaC - - ko:K03315 - - - - ko00000,ko02000 2.A.35 - - Na_H_antiporter k141_18772_1 1117647.M5M_17220 4.51e-68 221.0 COG0520@1|root,COG0520@2|Bacteria,1PJFE@1224|Proteobacteria,1RRJK@1236|Gammaproteobacteria,1JA4W@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E COG0520 Selenocysteine lyase - - - - - - - - - - - - Aminotran_5 k141_31449_1 344747.PM8797T_17979 5.15e-15 76.6 COG1595@1|root,COG1595@2|Bacteria,2IZPG@203682|Planctomycetes 203682|Planctomycetes K COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_27914_1 518766.Rmar_1990 2.21e-32 126.0 COG4257@1|root,COG4257@2|Bacteria 2|Bacteria V antibiotic catabolic process - - - ko:K18235 - - - - ko00000,ko01000,ko01504 - - - DUF5011 k141_10392_1 218284.CCDN010000002_gene2004 6.95e-113 333.0 COG0002@1|root,COG0002@2|Bacteria,1TPVI@1239|Firmicutes,4H9YD@91061|Bacilli,1ZBHP@1386|Bacillus 91061|Bacilli E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde argC GO:0003674,GO:0003824,GO:0003942,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.38 ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R03443 RC00684 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU11190 Semialdhyde_dh,Semialdhyde_dhC k141_12831_2 218284.CCDN010000002_gene2726 4.51e-28 108.0 COG1366@1|root,COG1366@2|Bacteria,1V1QF@1239|Firmicutes,4HGBT@91061|Bacilli,1ZDJX@1386|Bacillus 91061|Bacilli T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) - - - ko:K17763 - - - - ko00000,ko03021 - - - STAS k141_29267_1 223926.28805029 6.75e-188 535.0 COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,1RMEI@1236|Gammaproteobacteria,1XTGQ@135623|Vibrionales 135623|Vibrionales P Belongs to the ABC transporter superfamily dppD - - ko:K02031,ko:K02032 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - ABC_tran,oligo_HPY k141_29267_2 1116375.VEJY3_00200 2.86e-157 442.0 COG1011@1|root,COG1011@2|Bacteria,1QZ94@1224|Proteobacteria,1RZCU@1236|Gammaproteobacteria,1XVWJ@135623|Vibrionales 135623|Vibrionales S HAD-hyrolase-like - - - - - - - - - - - - HAD_2 k141_3047_1 218284.CCDN010000008_gene4220 2.17e-47 157.0 COG4980@1|root,COG4980@2|Bacteria,1VFY7@1239|Firmicutes,4HNWV@91061|Bacilli,1ZEKS@1386|Bacillus 91061|Bacilli S COG4980 Gas vesicle protein ytxH - - - - - - - - - - - YtxH k141_20878_1 1042377.AFPJ01000019_gene2533 4.15e-23 99.4 COG4242@1|root,COG4242@2|Bacteria,1PR9J@1224|Proteobacteria,1RVJH@1236|Gammaproteobacteria,469D6@72275|Alteromonadaceae 1236|Gammaproteobacteria PQ Peptidase family S51 cphB - 3.4.15.6 ko:K13282 - - R09722 RC00064,RC00141 ko00000,ko01000,ko01002 - - - Peptidase_S51 k141_20878_2 196627.cg2965 4.36e-11 71.2 COG2207@1|root,COG2207@2|Bacteria,2IC6B@201174|Actinobacteria,22RGU@1653|Corynebacteriaceae 201174|Actinobacteria K AraC-binding-like domain - - - - - - - - - - - - AraC_binding_2,HTH_18 k141_14098_2 1279017.AQYJ01000025_gene731 4.78e-268 740.0 COG1726@1|root,COG1726@2|Bacteria,1MU36@1224|Proteobacteria,1RPU1@1236|Gammaproteobacteria,464YM@72275|Alteromonadaceae 1236|Gammaproteobacteria C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol nqrA GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030001,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0051179,GO:0051234,GO:0055114,GO:0098796,GO:1902494 1.6.5.8 ko:K00346 - - - - ko00000,ko01000 - - - NQRA,NQRA_SLBB k141_11617_1 177439.DP0189 5.1e-18 80.9 28KC2@1|root,2Z9Z2@2|Bacteria,1RBTZ@1224|Proteobacteria,42XV5@68525|delta/epsilon subdivisions,2WT79@28221|Deltaproteobacteria 28221|Deltaproteobacteria S CRISPR-associated protein GSU0053 (Cas_GSU0053) csb1 - - ko:K19131 - - - - ko00000,ko02048 - - - Cas_GSU0053 k141_19821_1 42565.FP66_09440 2.18e-116 338.0 COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,1RMBU@1236|Gammaproteobacteria,1XHMZ@135619|Oceanospirillales 135619|Oceanospirillales H Belongs to the NadC ModD family nadC - 2.4.2.19 ko:K00767 ko00760,ko01100,map00760,map01100 M00115 R03348 RC02877 ko00000,ko00001,ko00002,ko01000 - - - QRPTase_C,QRPTase_N k141_22176_1 1294265.JCM21738_3786 1.64e-31 116.0 COG3842@1|root,COG3842@2|Bacteria,1V5RM@1239|Firmicutes,4HTCM@91061|Bacilli,1ZCVF@1386|Bacillus 91061|Bacilli E ATPases associated with a variety of cellular activities - - 3.6.3.55 ko:K06857 ko02010,map02010 M00186 R10531 RC00002 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.6.2,3.A.1.6.4 - - ABC_tran k141_22176_2 1294265.JCM21738_3787 1.82e-61 194.0 COG4662@1|root,COG4662@2|Bacteria,1TRK7@1239|Firmicutes,4HJMA@91061|Bacilli,1ZEEF@1386|Bacillus 91061|Bacilli H COG4662 ABC-type tungstate transport system, periplasmic component - - - ko:K05773 ko02010,map02010 M00186 - - ko00000,ko00001,ko00002,ko02000 3.A.1.6.2,3.A.1.6.4 - - BPD_transp_1 k141_27184_2 1116375.VEJY3_06865 1.19e-196 546.0 COG0829@1|root,COG0829@2|Bacteria,1RABD@1224|Proteobacteria,1RSB2@1236|Gammaproteobacteria,1XUYZ@135623|Vibrionales 135623|Vibrionales O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter ureD - - ko:K03190 - - - - ko00000 - - - UreD k141_27184_3 1116375.VEJY3_06870 5.09e-60 185.0 COG0831@1|root,COG0831@2|Bacteria,1RGXE@1224|Proteobacteria,1S65Y@1236|Gammaproteobacteria,1XXW0@135623|Vibrionales 135623|Vibrionales E Belongs to the urease gamma subunit family ureA - 3.5.1.5 ko:K01430,ko:K14048 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 - R00131 RC02798,RC02806 ko00000,ko00001,ko01000 - - - Urease_gamma k141_27184_4 1116375.VEJY3_06875 3.04e-66 201.0 COG0832@1|root,COG0832@2|Bacteria,1RGW0@1224|Proteobacteria,1S8UP@1236|Gammaproteobacteria,1XY5U@135623|Vibrionales 135623|Vibrionales E Belongs to the urease beta subunit family ureB - 3.5.1.5 ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 - R00131 RC02798,RC02806 ko00000,ko00001,ko01000 - - - Urease_beta k141_27184_5 1116375.VEJY3_06880 0.0 1127.0 COG0804@1|root,COG0804@2|Bacteria,1MU5P@1224|Proteobacteria,1RN78@1236|Gammaproteobacteria,1XVIJ@135623|Vibrionales 135623|Vibrionales E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family ureC - 3.5.1.5 ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 - R00131 RC02798,RC02806 ko00000,ko00001,ko01000 - - - Amidohydro_1,Urease_alpha k141_27184_6 1116375.VEJY3_06885 4.87e-101 293.0 COG2371@1|root,COG2371@2|Bacteria,1MZQZ@1224|Proteobacteria,1S6R9@1236|Gammaproteobacteria,1XWRZ@135623|Vibrionales 135623|Vibrionales O Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly ureE - - ko:K03187 - - - - ko00000 - - - UreE_C,UreE_N k141_1841_1 1116375.VEJY3_06845 4.78e-61 204.0 COG0559@1|root,COG0559@2|Bacteria,1MVND@1224|Proteobacteria,1RQXD@1236|Gammaproteobacteria,1XUB9@135623|Vibrionales 135623|Vibrionales E Belongs to the binding-protein-dependent transport system permease family urtB - - ko:K11960 ko02010,map02010 M00323 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4.4,3.A.1.4.5 - - BPD_transp_2 k141_1841_2 1116375.VEJY3_06840 1.09e-310 846.0 COG0683@1|root,COG0683@2|Bacteria,1MU8V@1224|Proteobacteria,1RMIJ@1236|Gammaproteobacteria,1XTRS@135623|Vibrionales 135623|Vibrionales E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component urtA - - ko:K11959 ko02010,map02010 M00323 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4.4,3.A.1.4.5 - - Peripla_BP_5 k141_1841_3 1116375.VEJY3_06835 1.04e-126 390.0 COG0642@1|root,COG0745@1|root,COG1457@1|root,COG0642@2|Bacteria,COG0745@2|Bacteria,COG1457@2|Bacteria,1NWAF@1224|Proteobacteria,1T4UY@1236|Gammaproteobacteria,1Y03V@135623|Vibrionales 135623|Vibrionales T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA,Response_reg k141_31450_1 1441930.Z042_16435 2.64e-52 177.0 COG1376@1|root,COG3926@1|root,COG1376@2|Bacteria,COG3926@2|Bacteria,1NANN@1224|Proteobacteria,1T0AX@1236|Gammaproteobacteria 1236|Gammaproteobacteria S L,D-transpeptidase catalytic domain - - - - - - - - - - - - YkuD_2 k141_32846_3 315749.Bcer98_2615 6.6e-15 72.8 COG1484@1|root,COG1484@2|Bacteria,1V5FC@1239|Firmicutes,4HI1I@91061|Bacilli,1ZGRE@1386|Bacillus 91061|Bacilli L IstB-like ATP binding protein - - - ko:K02315 - - - - ko00000,ko03032 - - - IstB_IS21 k141_35420_1 1283300.ATXB01000001_gene1642 1.17e-34 133.0 COG0145@1|root,COG0146@1|root,COG0145@2|Bacteria,COG0146@2|Bacteria,1MU2Y@1224|Proteobacteria,1RN6C@1236|Gammaproteobacteria,1XEBW@135618|Methylococcales 135618|Methylococcales EQ Hydantoinase B/oxoprolinase - - 3.5.2.9 ko:K01469 ko00480,map00480 - R00251 RC00553 ko00000,ko00001,ko01000 - - - Hydant_A_N,Hydantoinase_A,Hydantoinase_B k141_35420_2 756067.MicvaDRAFT_1476 2.21e-12 62.4 COG2442@1|root,COG2442@2|Bacteria,1GA44@1117|Cyanobacteria,1HC3P@1150|Oscillatoriales 1117|Cyanobacteria S Protein of unknown function (DUF433) - - - - - - - - - - - - DUF433 k141_27346_1 1042377.AFPJ01000052_gene1539 5.51e-59 196.0 COG5338@1|root,COG5338@2|Bacteria,1R56M@1224|Proteobacteria,1S0PC@1236|Gammaproteobacteria,464BC@72275|Alteromonadaceae 1236|Gammaproteobacteria S Putative beta-barrel porin 2 - - - ko:K20920 ko05111,map05111 - - - ko00000,ko00001,ko02000 1.B.66.3.1,1.B.66.3.2 - - BBP2_2 k141_20935_1 218284.CCDN010000001_gene1425 8.16e-82 270.0 COG4581@1|root,COG4581@2|Bacteria,1TRYX@1239|Firmicutes,4HU79@91061|Bacilli,1ZE6K@1386|Bacillus 91061|Bacilli L COG0513 Superfamily II DNA and RNA helicases - - 3.6.4.13 ko:K17675 - - - - ko00000,ko01000,ko03029 - - - Helicase_C k141_3158_1 218284.CCDN010000002_gene2068 6.52e-91 278.0 COG4191@1|root,COG4191@2|Bacteria,1UZ9W@1239|Firmicutes,4HDK2@91061|Bacilli,1ZD85@1386|Bacillus 91061|Bacilli T Histidine kinase kinB3 - 2.7.13.3 ko:K07697 ko02020,map02020 M00485 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - 5TM-5TMR_LYT,HATPase_c,HisKA k141_19922_1 218284.CCDN010000006_gene3549 2.6e-58 187.0 COG0664@1|root,COG0664@2|Bacteria 2|Bacteria T cyclic nucleotide binding crp2 - - ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 - - - ko00000,ko00001,ko03000 - - - HTH_Crp_2,cNMP_binding k141_16273_2 1042377.AFPJ01000024_gene816 8.89e-99 301.0 COG0705@1|root,COG0705@2|Bacteria,1MYPM@1224|Proteobacteria,1RN1K@1236|Gammaproteobacteria,463ZC@72275|Alteromonadaceae 1236|Gammaproteobacteria S membrane protein (homolog of Drosophila rhomboid) glpG GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019219,GO:0019222,GO:0019538,GO:0031224,GO:0031226,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042802,GO:0043170,GO:0043565,GO:0044212,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:0140096,GO:1901363,GO:1901564,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - ko:K02441 - - - - ko00000 - - - NRho,Rhomboid,Rhomboid_N k141_16273_3 1279017.AQYJ01000028_gene2164 3.44e-234 651.0 COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,1RND5@1236|Gammaproteobacteria,464ZN@72275|Alteromonadaceae 1236|Gammaproteobacteria CH COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases visC GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016491,GO:0019168,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901576,GO:1901661,GO:1901663 - ko:K03184,ko:K18800 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04987,R06146,R08768,R08775 RC00046,RC01254 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_3 k141_16273_4 1279017.AQYJ01000028_gene2163 7.72e-175 502.0 COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,1RMS3@1236|Gammaproteobacteria,464X1@72275|Alteromonadaceae 1236|Gammaproteobacteria CH COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases ubiH GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008681,GO:0009058,GO:0009108,GO:0009314,GO:0009416,GO:0009628,GO:0009987,GO:0016491,GO:0016705,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0050896,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901576,GO:1901661,GO:1901663 - ko:K03185,ko:K18800 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04987,R04989,R08768,R08773 RC00046,RC02670 ko00000,ko00001,ko00002,ko01000 - - iB21_1397.B21_02702,iECBD_1354.ECBD_0830,iECB_1328.ECB_02739,iECD_1391.ECD_02739,iEcHS_1320.EcHS_A3066 FAD_binding_3 k141_16273_5 1121937.AUHJ01000010_gene1651 1.28e-58 195.0 COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,1RN0W@1236|Gammaproteobacteria,464SX@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0006 Xaa-Pro aminopeptidase pepP - 3.4.11.9 ko:K01262 - - - - ko00000,ko01000,ko01002 - - - AMP_N,Peptidase_M24 k141_25961_1 1042377.AFPJ01000007_gene1884 1.59e-79 246.0 COG2828@1|root,COG2828@2|Bacteria,1MXVV@1224|Proteobacteria,1RNE6@1236|Gammaproteobacteria,464AI@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria prpF - - ko:K09788 ko00640,map00640 - R11264 RC03405 ko00000,ko00001,ko01000 - - - PrpF k141_25961_2 493475.GARC_1664 2.22e-11 63.2 COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,1RN5I@1236|Gammaproteobacteria,465HN@72275|Alteromonadaceae 1236|Gammaproteobacteria C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate acnD GO:0003674,GO:0003824,GO:0003994,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009060,GO:0009062,GO:0009987,GO:0015980,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019752,GO:0032787,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0045333,GO:0046395,GO:0046459,GO:0055114,GO:0071704,GO:0072329,GO:0072350,GO:1901575 4.2.1.117,4.2.1.3 ko:K01681,ko:K20455 ko00020,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900,R11263 RC00497,RC00498,RC00618,RC01152 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_C k141_9320_1 218284.CCDN010000005_gene3253 4.88e-138 395.0 COG1028@1|root,COG1028@2|Bacteria,1TR53@1239|Firmicutes,4HB8Y@91061|Bacilli,1ZAS0@1386|Bacillus 91061|Bacilli IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) yhxC - - - - - - - - - - - adh_short_C2 k141_22314_1 218284.CCDN010000005_gene3209 9.54e-199 557.0 COG2391@1|root,COG2391@2|Bacteria,1TSNG@1239|Firmicutes,4HCH9@91061|Bacilli,1ZBQW@1386|Bacillus 91061|Bacilli S Sulphur transport - - - ko:K07112 - - - - ko00000 - - - Sulf_transp k141_19923_1 1446473.JHWH01000011_gene927 8.74e-12 70.9 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQPG@28211|Alphaproteobacteria,2PVIB@265|Paracoccus 28211|Alphaproteobacteria T Sigma-54 interaction domain dctD - - ko:K10126 ko02020,map02020 M00504 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat k141_6903_1 1453501.JELR01000005_gene1594 1.39e-60 209.0 COG1501@1|root,COG1501@2|Bacteria,1MWNJ@1224|Proteobacteria,1RMJ9@1236|Gammaproteobacteria,465UA@72275|Alteromonadaceae 1236|Gammaproteobacteria G Belongs to the glycosyl hydrolase 31 family malZ GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016758,GO:0033825,GO:0046527 2.4.1.161,3.2.1.177,3.2.1.20 ko:K01187,ko:K01811,ko:K18820 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00028,R00801,R00802,R06087,R06088 RC00028,RC00049,RC00077 ko00000,ko00001,ko01000 - GH31 - CBM_20,DUF4968,DUF5110,Gal_mutarotas_2,Glyco_hydro_31,PA14 k141_6903_2 1279017.AQYJ01000028_gene2279 0.0 885.0 COG0366@1|root,COG0366@2|Bacteria,1Q8Y2@1224|Proteobacteria,1RQV0@1236|Gammaproteobacteria,464WX@72275|Alteromonadaceae 1236|Gammaproteobacteria G Alpha amylase, catalytic domain - - - - - - - - - - - - Alpha-amylase,Alpha-amylase_C,Malt_amylase_C k141_10432_1 218284.CCDN010000004_gene3096 3.3e-44 145.0 2BAGI@1|root,323X4@2|Bacteria,1UARE@1239|Firmicutes,4IM44@91061|Bacilli,1ZJ3I@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3889) - - - - - - - - - - - - DUF3889 k141_966_1 945550.VISI1226_09574 3.54e-89 269.0 COG0765@1|root,COG0765@2|Bacteria,1MX3E@1224|Proteobacteria,1SPYP@1236|Gammaproteobacteria,1Y2TY@135623|Vibrionales 135623|Vibrionales P COG0765 ABC-type amino acid transport system, permease component - - - ko:K02029 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 k141_966_2 1219076.N646_0690 1.71e-155 438.0 COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,1RMX1@1236|Gammaproteobacteria,1XUPN@135623|Vibrionales 135623|Vibrionales E ABC transporter glnQ - 3.6.3.21 ko:K02028 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran k141_966_3 392500.Swoo_1189 1.99e-93 273.0 COG0346@1|root,COG0346@2|Bacteria,1RGTU@1224|Proteobacteria,1S6TM@1236|Gammaproteobacteria,2QBQW@267890|Shewanellaceae 1236|Gammaproteobacteria E PFAM Glyoxalase bleomycin resistance protein dioxygenase - - 4.4.1.5 ko:K01759 ko00620,map00620 - R02530 RC00004,RC00740 ko00000,ko00001,ko01000 - - - Glyoxalase k141_966_4 1116375.VEJY3_08355 4.52e-118 340.0 COG1011@1|root,COG1011@2|Bacteria,1PGNF@1224|Proteobacteria,1RRDC@1236|Gammaproteobacteria,1XVRH@135623|Vibrionales 135623|Vibrionales S hydrolase (HAD superfamily) - - - ko:K07025 - - - - ko00000 - - - HAD_2 k141_966_5 1116375.VEJY3_08345 3.18e-71 217.0 COG0454@1|root,COG0456@2|Bacteria,1N98J@1224|Proteobacteria,1S9E3@1236|Gammaproteobacteria,1Y2X1@135623|Vibrionales 135623|Vibrionales K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1 k141_966_6 1462527.CCDM010000002_gene813 6.27e-27 106.0 COG5457@1|root,COG5457@2|Bacteria,1V2R9@1239|Firmicutes,4HG30@91061|Bacilli,23KV9@182709|Oceanobacillus 91061|Bacilli S Domain of unknown function (DUF1127) - - - - - - - - - - - - - k141_7945_1 218284.CCDN010000001_gene23 2.06e-123 358.0 COG0552@1|root,COG0552@2|Bacteria,1TPRI@1239|Firmicutes,4HA6A@91061|Bacilli,1ZB46@1386|Bacillus 91061|Bacilli U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) ftsY - - ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2,3.A.5.7 - - SRP54,SRP54_N k141_10442_2 218284.CCDN010000005_gene3178 3.55e-58 183.0 2CK8D@1|root,32SBU@2|Bacteria,1VAQG@1239|Firmicutes,4HHGS@91061|Bacilli,1ZF8Y@1386|Bacillus 91061|Bacilli S Tryptophan transporter TrpP trpP - - - - - - - - - - iYO844.BSU10010 TrpP k141_36342_1 1279017.AQYJ01000020_gene1298 2.16e-177 517.0 COG0500@1|root,COG1073@1|root,COG1073@2|Bacteria,COG2226@2|Bacteria,1PA5F@1224|Proteobacteria,1RY7A@1236|Gammaproteobacteria,465B1@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway bioC GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008757,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0010340,GO:0016053,GO:0016740,GO:0016741,GO:0016787,GO:0016788,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032259,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0052689,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.197 ko:K02169 ko00780,ko01100,map00780,map01100 M00572 R09543 RC00003,RC00460 ko00000,ko00001,ko00002,ko01000 - - iECP_1309.ECP_0791,iSBO_1134.SBO_0664,iSFV_1184.SFV_0760,iSF_1195.SF0727,iSFxv_1172.SFxv_0792,iSSON_1240.SSON_0756,iS_1188.S0768,iSbBS512_1146.SbBS512_E2575 Methyltransf_11 k141_36342_2 1279017.AQYJ01000020_gene1299 1.31e-180 515.0 COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,1RNS6@1236|Gammaproteobacteria,4655Y@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide bioF GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.47 ko:K00652 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R03210,R10124 RC00004,RC00039,RC02725 ko00000,ko00001,ko00002,ko01000,ko01007 - - iEC55989_1330.EC55989_0819,iECO111_1330.ECO111_0837,iECO26_1355.ECO26_0902,iSDY_1059.SDY_0830 Aminotran_1_2 k141_36342_3 1279017.AQYJ01000020_gene1300 3.29e-235 649.0 COG0502@1|root,COG0502@2|Bacteria,1MVFF@1224|Proteobacteria,1RMEQ@1236|Gammaproteobacteria,46540@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism bioB GO:0003674,GO:0003824,GO:0004076,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.6 ko:K01012 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R01078 RC00441 ko00000,ko00001,ko00002,ko01000 - - iZ_1308.Z0994 BATS,Radical_SAM k141_36342_4 1458357.BG58_00755 6e-24 103.0 COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,2VSPK@28216|Betaproteobacteria,1K0KN@119060|Burkholderiaceae 28216|Betaproteobacteria S Competence protein comF - - - - - - - - - - - Pribosyltran k141_36342_5 1279017.AQYJ01000020_gene1302 2.36e-226 629.0 COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,1RNIR@1236|Gammaproteobacteria,464PA@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG0332 3-oxoacyl- acyl-carrier-protein synthase III fabH - 2.3.1.207 ko:K16872 - - - - ko00000,ko01000 - - - ACP_syn_III,ACP_syn_III_C k141_36342_6 1279017.AQYJ01000020_gene1304 6.57e-65 204.0 2940Y@1|root,2ZRFS@2|Bacteria,1RF8A@1224|Proteobacteria,1RZCB@1236|Gammaproteobacteria 1236|Gammaproteobacteria U L-alanine exporter AlaE alaE GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015077,GO:0015078,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015562,GO:0015672,GO:0015711,GO:0015804,GO:0015807,GO:0015808,GO:0015849,GO:0016020,GO:0022804,GO:0022857,GO:0022890,GO:0032328,GO:0034220,GO:0034639,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:0098660,GO:0098662,GO:1902475,GO:1902600,GO:1903825,GO:1905039 - - - - - - - - - - AlaE k141_36342_7 1279017.AQYJ01000020_gene1306 6.69e-38 148.0 COG0784@1|root,COG0784@2|Bacteria,1P06Y@1224|Proteobacteria 1224|Proteobacteria T cheY-homologous receiver domain - - - - - - - - - - - - Hpt,Response_reg k141_36342_9 1279017.AQYJ01000020_gene1309 1.03e-139 412.0 COG5339@1|root,COG5339@2|Bacteria,1QPEJ@1224|Proteobacteria,1SJ4D@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Bacterial protein of unknown function (DUF945) - - - - - - - - - - - - DUF945 k141_36342_11 1279017.AQYJ01000020_gene1316 4.51e-175 509.0 COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,1RM95@1236|Gammaproteobacteria,465G3@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG4770 Acetyl propionyl-CoA carboxylase, alpha subunit mccA - 6.4.1.4 ko:K01968 ko00280,ko01100,map00280,map01100 M00036 R04138 RC00367,RC00942 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2 k141_25988_1 768066.HELO_1134 3.4e-117 345.0 COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,1RNB5@1236|Gammaproteobacteria,1XHZR@135619|Oceanospirillales 135619|Oceanospirillales C L-carnitine dehydratase bile acid-inducible protein F - - 2.8.3.19 ko:K18702 - - - - ko00000,ko01000 - - - CoA_transf_3 k141_23682_1 218284.CCDN010000005_gene3194 7.04e-148 427.0 COG1232@1|root,COG1232@2|Bacteria,1TQ6W@1239|Firmicutes,4HAUG@91061|Bacilli,1ZANK@1386|Bacillus 91061|Bacilli H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX hemY - 1.3.3.15,1.3.3.4 ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03222,R04178 RC00885 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS09325 Amino_oxidase k141_37563_1 1385517.N800_07975 2.96e-49 166.0 28JZ9@1|root,2Z9PC@2|Bacteria,1R7GE@1224|Proteobacteria,1S7TF@1236|Gammaproteobacteria,1X5FZ@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - k141_37563_2 247634.GPB2148_3772 8.24e-22 89.0 COG1917@1|root,COG1917@2|Bacteria,1N0G1@1224|Proteobacteria,1SDYY@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Pfam Cupin - - - - - - - - - - - - Cupin_2 k141_5722_1 1283284.AZUK01000001_gene2458 1.75e-23 95.5 COG0561@1|root,COG0561@2|Bacteria,1Q5HK@1224|Proteobacteria,1RQ8H@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Hydrolase - - - - - - - - - - - - Hydrolase_3 k141_5722_2 1116375.VEJY3_06555 1.17e-168 473.0 COG1349@1|root,COG1349@2|Bacteria,1MXW2@1224|Proteobacteria,1RQDR@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Transcriptional Regulator, DeoR family - - - - - - - - - - - - DeoRC,HTH_DeoR k141_1901_1 218284.CCDN010000002_gene2266 3e-160 460.0 COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,1TPXQ@1239|Firmicutes,4HA3C@91061|Bacilli,1ZBHE@1386|Bacillus 91061|Bacilli C Catalyzes the reversible hydration of fumarate to (S)- malate fumA - 4.2.1.2 ko:K01676 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - - Fumerase,Fumerase_C k141_9352_1 1042377.AFPJ01000035_gene2653 1.14e-96 302.0 COG3590@1|root,COG3590@2|Bacteria,1MVNQ@1224|Proteobacteria,1RNNA@1236|Gammaproteobacteria,464DA@72275|Alteromonadaceae 1236|Gammaproteobacteria O Peptidase, M13 pepO - 3.4.24.71 ko:K01415,ko:K07386 - - - - ko00000,ko01000,ko01002,ko04147 - - - Peptidase_M13,Peptidase_M13_N k141_7946_1 742743.HMPREF9453_02067 1.39e-06 56.6 COG0419@1|root,COG0419@2|Bacteria,1TPCS@1239|Firmicutes,4H39J@909932|Negativicutes 909932|Negativicutes L Exonuclease SbcC sbcC - - ko:K03546 - - - - ko00000,ko03400 - - - AAA_23,SbcCD_C k141_18970_1 1379698.RBG1_1C00001G0521 4.16e-79 249.0 COG1071@1|root,COG1071@2|Bacteria,2NPBB@2323|unclassified Bacteria 2|Bacteria C Dehydrogenase E1 component bfmBA - 1.2.4.1,1.2.4.4 ko:K00161,ko:K00166,ko:K11381,ko:K21416 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00036,M00307 R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh,Transket_pyr,Transketolase_C k141_18970_2 62928.azo3868 2.6e-15 75.5 COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,2VKQ0@28216|Betaproteobacteria,2KY7R@206389|Rhodocyclales 206389|Rhodocyclales C Transketolase, pyrimidine binding domain - - - ko:K21417 - - - - ko00000,ko01000 - - - Transket_pyr,Transketolase_C k141_997_3 997296.PB1_10117 5.81e-22 92.4 2E2ZD@1|root,32Y01@2|Bacteria,1VHQD@1239|Firmicutes,4HNXI@91061|Bacilli,1ZIWQ@1386|Bacillus 91061|Bacilli - - yuzC - - - - - - - - - - - - k141_35435_1 1123236.KB899376_gene558 2.71e-53 169.0 COG0290@1|root,COG0290@2|Bacteria,1RDD2@1224|Proteobacteria,1S4E6@1236|Gammaproteobacteria,466GC@72275|Alteromonadaceae 1236|Gammaproteobacteria J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins infC GO:0000049,GO:0001731,GO:0002181,GO:0002183,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016020,GO:0016043,GO:0019222,GO:0019538,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032268,GO:0032270,GO:0032790,GO:0032984,GO:0032988,GO:0032991,GO:0034248,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043254,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045727,GO:0045948,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065003,GO:0065007,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:1901193,GO:1901195,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:1904688,GO:1904690,GO:1990856,GO:1990904,GO:2000112,GO:2000765,GO:2000767 - ko:K02520 - - - - ko00000,ko03012,ko03029 - - - IF3_C,IF3_N k141_35435_2 455436.DS989810_gene180 7.4e-21 83.2 COG0291@1|root,COG0291@2|Bacteria,1N6V4@1224|Proteobacteria,1SCHI@1236|Gammaproteobacteria,468CG@72275|Alteromonadaceae 1236|Gammaproteobacteria J Belongs to the bacterial ribosomal protein bL35 family rpmI GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02916 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L35p k141_15051_2 218284.CCDN010000001_gene939 1.09e-167 482.0 COG0553@1|root,COG0553@2|Bacteria,1TQ5E@1239|Firmicutes,4H9WB@91061|Bacilli,1ZAR5@1386|Bacillus 91061|Bacilli L COG0553 Superfamily II DNA RNA helicases, SNF2 family yqhH - - - - - - - - - - - Helicase_C,SNF2_N k141_11712_1 198467.NP92_05160 5.95e-107 320.0 COG1653@1|root,COG1653@2|Bacteria,1TQ0V@1239|Firmicutes,4HA7Z@91061|Bacilli,21WMI@150247|Anoxybacillus 91061|Bacilli G Bacterial extracellular solute-binding protein lacE - - ko:K10188 ko02010,map02010 M00199 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.4 - - SBP_bac_8 k141_30355_1 399739.Pmen_3182 6.85e-22 100.0 COG0515@1|root,COG0515@2|Bacteria,1MVEU@1224|Proteobacteria,1SYEH@1236|Gammaproteobacteria,1YFQM@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria KLT Protein tyrosine kinase - - 2.7.11.1 ko:K08884,ko:K11912 ko02025,ko03070,map02025,map03070 - - - ko00000,ko00001,ko01000,ko01001,ko02044 - - - Pkinase k141_30355_2 1454004.AW11_03381 9.17e-18 86.7 COG3386@1|root,COG3386@2|Bacteria,1QW76@1224|Proteobacteria 1224|Proteobacteria G PFAM SMP-30 Gluconolaconase - - - - - - - - - - - - - k141_16288_1 1279017.AQYJ01000024_gene1194 2.98e-47 157.0 COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,1RMSS@1236|Gammaproteobacteria,4651Y@72275|Alteromonadaceae 1236|Gammaproteobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_int_SAM_4,Phage_integrase k141_3173_1 1453501.JELR01000002_gene1510 2.06e-185 527.0 COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,1RMWS@1236|Gammaproteobacteria,4646Q@72275|Alteromonadaceae 1236|Gammaproteobacteria F COG0138 AICAR transformylase IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) purH GO:0003674,GO:0003824,GO:0004643,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 - - iEcHS_1320.EcHS_A4240,iPC815.YPO3728 AICARFT_IMPCHas,MGS k141_19945_1 1356854.N007_14960 5.64e-13 69.3 COG2202@1|root,COG3852@1|root,COG2202@2|Bacteria,COG3852@2|Bacteria,1TRH0@1239|Firmicutes,4HD4A@91061|Bacilli,2799P@186823|Alicyclobacillaceae 91061|Bacilli T PAS fold - - 2.7.13.3 ko:K02491 ko02020,map02020 M00485 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - 5TM-5TMR_LYT,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9 k141_19945_2 218284.CCDN010000001_gene1438 1.3e-39 133.0 2E4AM@1|root,32XKC@2|Bacteria,1VE9E@1239|Firmicutes,4HN07@91061|Bacilli,1ZJ0J@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_24663_1 1453501.JELR01000002_gene385 1.66e-113 335.0 COG0715@1|root,COG0715@2|Bacteria,1MWDN@1224|Proteobacteria,1RPUP@1236|Gammaproteobacteria,46702@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components - - - ko:K22067 - - - - ko00000,ko02022 - - - NMT1_2 k141_35436_1 208439.AJAP_41340 6.79e-13 66.6 COG3576@1|root,COG3576@2|Bacteria,2IKU6@201174|Actinobacteria,4EBVG@85010|Pseudonocardiales 201174|Actinobacteria S Pyridoxamine 5'-phosphate oxidase - - - - - - - - - - - - Putative_PNPOx k141_4366_2 1116375.VEJY3_04500 4.95e-113 326.0 COG1670@1|root,COG1670@2|Bacteria,1RKE8@1224|Proteobacteria,1SU1I@1236|Gammaproteobacteria,1XWX4@135623|Vibrionales 135623|Vibrionales J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins - - - - - - - - - - - - Acetyltransf_3 k141_4366_3 1116375.VEJY3_04505 1.11e-147 419.0 2EC19@1|root,3360G@2|Bacteria,1N87W@1224|Proteobacteria,1S7E3@1236|Gammaproteobacteria,1XSJF@135623|Vibrionales 135623|Vibrionales S Peptidoglycan-binding protein, CsiV pgs1 - - - - - - - - - - - CsiV k141_4366_4 1116375.VEJY3_04510 0.0 2175.0 COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,1RNCU@1236|Gammaproteobacteria,1XSMS@135623|Vibrionales 135623|Vibrionales L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd - - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF k141_4366_5 674977.VMC_30980 4.95e-105 306.0 2CHGH@1|root,32S61@2|Bacteria,1MZN3@1224|Proteobacteria,1S9S8@1236|Gammaproteobacteria,1XUJE@135623|Vibrionales 135623|Vibrionales - - VV12079 - - - - - - - - - - - - k141_4366_6 1116375.VEJY3_04520 4.27e-258 711.0 COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,1RMP9@1236|Gammaproteobacteria,1XSMT@135623|Vibrionales 135623|Vibrionales M COG4591 ABC-type transport system, involved in lipoprotein release, permease component lolC - - ko:K09808 ko02010,map02010 M00255 - - ko00000,ko00001,ko00002,ko02000 3.A.1.125 - - FtsX,MacB_PCD k141_4366_7 1116375.VEJY3_04525 3.35e-153 432.0 COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,1RMWK@1236|Gammaproteobacteria,1XTZP@135623|Vibrionales 135623|Vibrionales V Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner lolD GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0008150,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085 - ko:K09810 ko02010,map02010 M00255 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.125 - - ABC_tran k141_4366_8 1116375.VEJY3_04530 1.78e-256 708.0 COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,1RMP9@1236|Gammaproteobacteria,1XSJ2@135623|Vibrionales 135623|Vibrionales M COG4591 ABC-type transport system, involved in lipoprotein release, permease component lolE - - ko:K09808 ko02010,map02010 M00255 - - ko00000,ko00001,ko00002,ko02000 3.A.1.125 - - FtsX,MacB_PCD k141_4366_9 1116375.VEJY3_04535 2.95e-110 318.0 COG3216@1|root,COG3216@2|Bacteria,1RGV6@1224|Proteobacteria,1S682@1236|Gammaproteobacteria,1XSNS@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria TLL0138 - - ko:K09928 - - - - ko00000 - - - DUF2062 k141_4366_10 1219076.N646_0047 0.0 988.0 COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1MUKF@1224|Proteobacteria,1RMW6@1236|Gammaproteobacteria,1XVBD@135623|Vibrionales 135623|Vibrionales S membrane metal-binding protein - - - ko:K02238 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - Competence,DUF4131,Lactamase_B k141_4366_11 1116375.VEJY3_04545 0.0 1039.0 COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria,1XTCT@135623|Vibrionales 135623|Vibrionales V Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation msbA GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005488,GO:0005515,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0042802,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702 - ko:K11085 ko02010,map02010 - - - ko00000,ko00001,ko01000,ko02000 3.A.1.106 - - ABC_membrane,ABC_tran k141_4366_12 1116375.VEJY3_04550 8.7e-215 596.0 COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,1RMMW@1236|Gammaproteobacteria,1XU8K@135623|Vibrionales 135623|Vibrionales F Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) lpxK GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009029,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.7.1.130 ko:K00912 ko00540,ko01100,map00540,map01100 M00060 R04657 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 - - - LpxK k141_4366_13 345073.VC395_1991 4.22e-36 122.0 COG2835@1|root,COG2835@2|Bacteria,1N6Y2@1224|Proteobacteria,1SCFF@1236|Gammaproteobacteria,1XYYD@135623|Vibrionales 135623|Vibrionales S Belongs to the UPF0434 family - - - ko:K09791 - - - - ko00000 - - - Trm112p k141_4366_14 1280001.BAOA01000060_gene2375 1.61e-100 296.0 COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,1RMAE@1236|Gammaproteobacteria,1XTK4@135623|Vibrionales 135623|Vibrionales M Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria kdsB GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008690,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0046401,GO:0070567,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.7.38 ko:K00979 ko00540,ko01100,map00540,map01100 M00063 R03351,R11396 RC00152,RC00910 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CTP_transf_3 k141_11713_1 218284.CCDN010000007_gene3908 1.09e-99 300.0 COG3314@1|root,COG3314@2|Bacteria,1TR35@1239|Firmicutes,4HAB6@91061|Bacilli,1ZARZ@1386|Bacillus 91061|Bacilli S protein conserved in bacteria - - - - - - - - - - - - Gate k141_32877_2 935837.JAEK01000023_gene1219 4.91e-57 188.0 COG1055@1|root,COG1055@2|Bacteria,1TPNN@1239|Firmicutes,4H9WV@91061|Bacilli,1ZBHC@1386|Bacillus 91061|Bacilli P Involved in arsenical resistance. Thought to form the channel of an arsenite pump ydfA - - ko:K03893 - - - - ko00000,ko02000 2.A.45.1,3.A.4.1 - - ArsB k141_27986_1 1453501.JELR01000005_gene1643 3.17e-89 265.0 2E3UE@1|root,32YRS@2|Bacteria,1N75A@1224|Proteobacteria,1S9W5@1236|Gammaproteobacteria,468Q7@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF2799) - - - - - - - - - - - - DUF2799 k141_9355_1 218284.CCDN010000001_gene1506 9.99e-117 358.0 COG1048@1|root,COG1048@2|Bacteria,1VTMM@1239|Firmicutes,4HB5N@91061|Bacilli,1ZART@1386|Bacillus 91061|Bacilli C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate citB GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0043937,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0050789,GO:0050793,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0065007,GO:0071704,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_C k141_34176_1 1123237.Salmuc_03477 8.33e-93 278.0 COG3246@1|root,COG3246@2|Bacteria,1MZTP@1224|Proteobacteria,2TQKN@28211|Alphaproteobacteria 28211|Alphaproteobacteria S PFAM Prokaryotic protein of - - - - - - - - - - - - BKACE k141_23685_1 1405.DJ92_821 6.52e-165 473.0 COG1418@1|root,COG1418@2|Bacteria,1TP48@1239|Firmicutes,4HC9J@91061|Bacilli,1ZBGP@1386|Bacillus 91061|Bacilli S Endoribonuclease that initiates mRNA decay rny GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K18682 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - DUF3552,HD,KH_1 k141_19946_1 1294265.JCM21738_5028 3.07e-65 198.0 COG2151@1|root,COG2151@2|Bacteria 2|Bacteria L metal-sulfur cluster biosynthetic enzyme yitW - - ko:K02612 ko00360,ko01120,map00360,map01120 - R09838 RC02690 ko00000,ko00001 - - - FeS_assembly_P k141_29351_1 1279017.AQYJ01000019_gene1515 1.07e-237 666.0 COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,1RNKA@1236|Gammaproteobacteria,464PF@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source nadE - 6.3.1.5,6.3.5.1 ko:K01916,ko:K01950 ko00760,ko01100,map00760,map01100 M00115 R00189,R00257 RC00010,RC00100 ko00000,ko00001,ko00002,ko01000 - - - CN_hydrolase,NAD_synthase k141_29351_3 1453501.JELR01000005_gene1787 3.54e-167 474.0 COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,1RN7F@1236|Gammaproteobacteria,4643F@72275|Alteromonadaceae 1236|Gammaproteobacteria J Responsible for synthesis of pseudouridine from uracil rluD GO:0000027,GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022607,GO:0022613,GO:0022618,GO:0031118,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 ko:K06180 - - - - ko00000,ko01000,ko03009 - - iE2348C_1286.E2348C_2868,iECED1_1282.ECED1_3035,iECSF_1327.ECSF_2432 PseudoU_synth_2,S4 k141_29351_4 1279017.AQYJ01000019_gene1518 8.43e-129 372.0 COG1496@1|root,COG1496@2|Bacteria,1MW2H@1224|Proteobacteria,1RNV4@1236|Gammaproteobacteria,466CB@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the multicopper oxidase YfiH RL5 family yfiH GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0016491,GO:0016679,GO:0016682,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0046983,GO:0055114 - ko:K05810 - - - - ko00000,ko01000 - - - Cu-oxidase_4 k141_29351_5 1279017.AQYJ01000019_gene1519 0.0 1510.0 COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,1RN55@1236|Gammaproteobacteria,4648S@72275|Alteromonadaceae 1236|Gammaproteobacteria O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE clpB GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009408,GO:0009628,GO:0010033,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0031249,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0035966,GO:0036094,GO:0042221,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 - ko:K03695 ko04213,map04213 - - - ko00000,ko00001,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N k141_29351_6 391615.ABSJ01000042_gene2220 3.81e-109 332.0 COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,1RQJ9@1236|Gammaproteobacteria,1J5WC@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K03585 ko01501,ko01503,map01501,map01503 M00646,M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,8.A.1.6 - - HlyD_D23 k141_29351_7 1453501.JELR01000005_gene1791 0.0 1329.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,464CD@72275|Alteromonadaceae 1236|Gammaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family mtrD_1 - - ko:K18138,ko:K18307 ko01501,ko01503,ko02024,map01501,map01503,map02024 M00644,M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2,2.A.6.2.20,2.A.6.2.32 - - ACR_tran k141_22505_1 223926.28806187 0.0 1104.0 COG0247@1|root,COG0493@1|root,COG0247@2|Bacteria,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,1S1QA@1236|Gammaproteobacteria,1XTJ8@135623|Vibrionales 135623|Vibrionales C Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - - - - - - - - - - Fer4_17,Fer4_20,Pyr_redox_2 k141_22505_2 1280001.BAOA01000078_gene3131 1.31e-129 375.0 COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,1SN04@1236|Gammaproteobacteria,1XURU@135623|Vibrionales 135623|Vibrionales P Rhodanese Homology Domain - - 2.8.1.1,2.8.1.2 ko:K01011 ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122 - R01931,R03105,R03106 RC00214 ko00000,ko00001,ko01000 - - - Rhodanese k141_17482_1 1294265.JCM21738_3783 4.85e-147 424.0 COG0642@1|root,COG2205@2|Bacteria,1V10X@1239|Firmicutes,4HAU7@91061|Bacilli,1ZB6A@1386|Bacillus 91061|Bacilli T Histidine kinase - - - - - - - - - - - - HAMP,HATPase_c,HisKA k141_28102_1 983917.RGE_35840 4.48e-23 90.1 COG1773@1|root,COG1773@2|Bacteria,1N6TQ@1224|Proteobacteria,2VWD0@28216|Betaproteobacteria,1KMQ9@119065|unclassified Burkholderiales 28216|Betaproteobacteria C Rubredoxin hoxR - - - - - - - - - - - Rubredoxin k141_28102_2 1121033.AUCF01000023_gene48 8.14e-32 120.0 COG1773@1|root,COG1773@2|Bacteria,1MV2U@1224|Proteobacteria,2TV0P@28211|Alphaproteobacteria,2JTAD@204441|Rhodospirillales 204441|Rhodospirillales C HupH hydrogenase expression protein, C-terminal conserved region - - - ko:K03618 - - - - ko00000 - - - HupH_C k141_7130_2 218284.CCDN010000008_gene4199 1.65e-105 308.0 COG0510@1|root,COG0510@2|Bacteria,1UMFY@1239|Firmicutes,4HBF9@91061|Bacilli,1ZC4H@1386|Bacillus 91061|Bacilli M Phosphotransferase ytmP - - - - - - - - - - - APH k141_1122_1 1279017.AQYJ01000023_gene3170 3.92e-118 353.0 COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,1RM98@1236|Gammaproteobacteria,465ZI@72275|Alteromonadaceae 1236|Gammaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoC GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 ko:K13378 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - iECDH10B_1368.ECDH10B_2448,iECDH1ME8569_1439.ECDH1ME8569_2223,iETEC_1333.ETEC_2421,iEcDH1_1363.EcDH1_1371,iPC815.YPO2553,iUMNK88_1353.UMNK88_2836 Complex1_30kDa,Complex1_49kDa k141_26108_1 1042377.AFPJ01000051_gene106 1.34e-51 169.0 COG0627@1|root,COG0627@2|Bacteria,1MUID@1224|Proteobacteria,1RMR3@1236|Gammaproteobacteria,46528@72275|Alteromonadaceae 1236|Gammaproteobacteria S Serine hydrolase involved in the detoxification of formaldehyde yeiG GO:0003674,GO:0003824,GO:0004416,GO:0005488,GO:0005515,GO:0006081,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010033,GO:0016043,GO:0016787,GO:0016788,GO:0016790,GO:0016999,GO:0017001,GO:0017144,GO:0018738,GO:0022607,GO:0042221,GO:0042802,GO:0043933,GO:0044085,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046185,GO:0046292,GO:0046294,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051716,GO:0065003,GO:0070887,GO:0071704,GO:0071840,GO:0097237,GO:0098754,GO:0110095,GO:0110096,GO:1901575,GO:1901700,GO:1901701,GO:1990748 3.1.2.12 ko:K01070 ko00680,ko01120,ko01200,map00680,map01120,map01200 - R00527 RC00167,RC00320 ko00000,ko00001,ko01000 - CE1 iAF1260.b0355,iBWG_1329.BWG_0244,iE2348C_1286.E2348C_2300,iECDH10B_1368.ECDH10B_0310,iECDH1ME8569_1439.ECDH1ME8569_0342,iEcDH1_1363.EcDH1_3251,iG2583_1286.G2583_0468,iJO1366.b0355,iY75_1357.Y75_RS01830 Esterase k141_4475_1 218284.CCDN010000001_gene962 1.59e-131 383.0 COG0439@1|root,COG0439@2|Bacteria,1TP16@1239|Firmicutes,4HARK@91061|Bacilli,1ZC56@1386|Bacillus 91061|Bacilli I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism accC - 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 k141_17484_1 218284.CCDN010000001_gene1049 1.91e-118 351.0 COG0697@1|root,COG0697@2|Bacteria,1TP7K@1239|Firmicutes,4HBWN@91061|Bacilli,1ZB54@1386|Bacillus 91061|Bacilli EG Stage V sporulation protein AF spoVAF - - ko:K06408 - - - - ko00000 - - - GerA k141_28123_1 223926.28805941 8.62e-153 431.0 COG0566@1|root,COG0566@2|Bacteria,1R9JA@1224|Proteobacteria,1RY04@1236|Gammaproteobacteria,1XUGN@135623|Vibrionales 135623|Vibrionales H COG0566 rRNA methylases - - - ko:K03437 - - - - ko00000,ko03016 - - - SpoU_methylase k141_28123_2 1116375.VEJY3_04430 7.81e-74 221.0 COG1146@1|root,COG1146@2|Bacteria,1RH5I@1224|Proteobacteria,1S5ZK@1236|Gammaproteobacteria,1XXFH@135623|Vibrionales 135623|Vibrionales C Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions fdxA - - ko:K05524 - - - - ko00000 - - - DUF3470,Fer4,Fer4_9 k141_28123_3 1116375.VEJY3_04435 0.0 985.0 COG2509@1|root,COG2509@2|Bacteria,1MV6P@1224|Proteobacteria,1RPTW@1236|Gammaproteobacteria,1XVBT@135623|Vibrionales 135623|Vibrionales S FAD-dependent dehydrogenases - - - ko:K07137 - - - - ko00000 - - - Amino_oxidase,FAD_binding_3 k141_16429_2 1453501.JELR01000002_gene950 0.0 1363.0 COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,1RM7J@1236|Gammaproteobacteria,464YC@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG5009 Membrane carboxypeptidase penicillin-binding protein mrcA GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0008955,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - PCB_OB,Transgly,Transpeptidase k141_5866_1 1380386.JIAW01000019_gene2367 3.23e-08 59.3 COG1309@1|root,COG1309@2|Bacteria,2GP92@201174|Actinobacteria,234M0@1762|Mycobacteriaceae 201174|Actinobacteria K tetR family - - - - - - - - - - - - TetR_N k141_26132_1 1294265.JCM21738_3665 1.76e-70 222.0 COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,4HB31@91061|Bacilli,1ZARE@1386|Bacillus 91061|Bacilli EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia pabB GO:0000162,GO:0000287,GO:0003674,GO:0003824,GO:0004049,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006575,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009108,GO:0009308,GO:0009309,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042398,GO:0042401,GO:0042430,GO:0042435,GO:0042558,GO:0042559,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 2.6.1.85 ko:K01665 ko00790,map00790 - R01716 RC00010,RC01418 ko00000,ko00001,ko01000 - - - Anth_synt_I_N,Chorismate_bind k141_30444_1 1294265.JCM21738_477 3.38e-77 234.0 COG2364@1|root,COG2364@2|Bacteria,1V3NC@1239|Firmicutes,4HGRQ@91061|Bacilli,1ZCBH@1386|Bacillus 91061|Bacilli S Membrane - - - ko:K07149 - - - - ko00000 - - - YitT_membrane k141_35591_1 218284.CCDN010000005_gene3201 4.18e-174 498.0 COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HA2G@91061|Bacilli,1ZBE5@1386|Bacillus 91061|Bacilli IQ Activates fatty acids by binding to coenzyme A lcfB_2 - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding,AMP-binding_C k141_2040_2 218284.CCDN010000005_gene3212 3.28e-133 382.0 COG1296@1|root,COG1296@2|Bacteria,1TSXD@1239|Firmicutes,4HJCQ@91061|Bacilli,1ZDNM@1386|Bacillus 91061|Bacilli E branched-chain amino acid - - - - - - - - - - - - AzlC k141_3297_1 203122.Sde_2500 8.27e-75 249.0 COG1501@1|root,COG1501@2|Bacteria,1MWNJ@1224|Proteobacteria,1RMJ9@1236|Gammaproteobacteria,465UA@72275|Alteromonadaceae 1236|Gammaproteobacteria G Belongs to the glycosyl hydrolase 31 family xylS - 2.4.1.161,3.2.1.177 ko:K01811,ko:K18820 - - - - ko00000,ko01000 - GH31 - DUF4968,DUF5110,Gal_mutarotas_2,Glyco_hydro_31,PA14 k141_17518_1 511062.GU3_03810 2.57e-37 140.0 COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,1RMBG@1236|Gammaproteobacteria,1Y3TV@135624|Aeromonadales 135624|Aeromonadales J Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control pcnB - 2.7.7.19 ko:K00970 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - PolyA_pol,PolyA_pol_RNAbd,PolyA_pol_arg_C k141_33015_1 315749.Bcer98_1774 7.61e-65 213.0 COG1232@1|root,COG1232@2|Bacteria,1TQ6W@1239|Firmicutes,4HAUG@91061|Bacilli,1ZANK@1386|Bacillus 91061|Bacilli H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX hemG - 1.3.3.15,1.3.3.4 ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03222,R04178 RC00885 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS09325 Amino_oxidase k141_34288_1 1453501.JELR01000002_gene828 7.27e-60 193.0 COG1638@1|root,COG1638@2|Bacteria,1MVHC@1224|Proteobacteria,1RPNJ@1236|Gammaproteobacteria,464A3@72275|Alteromonadaceae 1236|Gammaproteobacteria G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component - - - - - - - - - - - - DctP k141_5867_1 406124.ACPC01000019_gene3088 6.63e-125 363.0 COG1363@1|root,COG1363@2|Bacteria,1TNZT@1239|Firmicutes,4H9SM@91061|Bacilli,1ZD06@1386|Bacillus 91061|Bacilli G COG1363 Cellulase M and related proteins ysdC - - - - - - - - - - - Peptidase_M42 k141_16430_1 1385512.N784_13700 1.82e-113 331.0 COG2207@1|root,COG3708@1|root,COG2207@2|Bacteria,COG3708@2|Bacteria,1TPI9@1239|Firmicutes,4HCJ8@91061|Bacilli,2YB73@289201|Pontibacillus 91061|Bacilli K AraC family transcriptional regulator ydeE7 - - ko:K13653 - - - - ko00000,ko03000 - - - Cass2,GyrI-like,HTH_18 k141_11871_2 218284.CCDN010000008_gene4135 5.52e-112 330.0 COG0448@1|root,COG0448@2|Bacteria,1TPZ3@1239|Firmicutes,4H9UQ@91061|Bacilli,1ZBVM@1386|Bacillus 91061|Bacilli G Glucose-1-phosphate adenylyltransferase, GlgD subunit glgD - 2.7.7.27 ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transferase k141_2041_1 1234664.AMRO01000056_gene301 9.87e-14 65.9 arCOG05874@1|root,2ZJ01@2|Bacteria,1V450@1239|Firmicutes,4HFPA@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - k141_30445_1 1382356.JQMP01000004_gene231 6.44e-69 221.0 COG3552@1|root,COG3552@2|Bacteria,2G5IW@200795|Chloroflexi,27XNE@189775|Thermomicrobia 189775|Thermomicrobia S VWA domain containing CoxE-like protein - - - ko:K07161 - - - - ko00000 - - - VWA_CoxE k141_34289_1 491915.Aflv_1045 2.92e-46 162.0 COG0079@1|root,COG0079@2|Bacteria,1TP5D@1239|Firmicutes,4HD85@91061|Bacilli,21VGX@150247|Anoxybacillus 91061|Bacilli E Aminotransferase class I and II cobD - 4.1.1.81 ko:K04720 ko00860,map00860 - R06530 RC00517 ko00000,ko00001,ko01000 - - - Aminotran_1_2 k141_1136_2 1116375.VEJY3_23691 0.0 933.0 COG0366@1|root,COG0366@2|Bacteria,1MU90@1224|Proteobacteria,1RQ1S@1236|Gammaproteobacteria,1XURK@135623|Vibrionales 135623|Vibrionales G alpha-amylase malS - 3.2.1.1 ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 - R02108,R02112,R11262 - ko00000,ko00001,ko01000 - GH13 - Alpha-amylase k141_21062_1 388739.RSK20926_05017 9.98e-56 196.0 COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,2TXAW@28211|Alphaproteobacteria,2P46E@2433|Roseobacter 28211|Alphaproteobacteria S metal-dependent hydrolase with the TIM-barrel fold - - - - - - - - - - - - Amidohydro_3 k141_11872_1 42565.FP66_10130 6.56e-113 335.0 COG3314@1|root,COG3314@2|Bacteria,1NEAN@1224|Proteobacteria,1RPX6@1236|Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - Gate k141_33017_2 1321782.HMPREF1986_00512 9.04e-11 64.7 COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,247RM@186801|Clostridia,2PRP2@265975|Oribacterium 186801|Clostridia L DNA helicase pcrA - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C k141_5868_1 366602.Caul_1853 1.29e-147 432.0 COG0446@1|root,COG0446@2|Bacteria,1Q0P8@1224|Proteobacteria,2U4CV@28211|Alphaproteobacteria,2KK7B@204458|Caulobacterales 204458|Caulobacterales S Tryptophan halogenase - - 1.14.19.9 ko:K14266 ko00404,ko01130,map00404,map01130 M00789,M00790 R09570 RC00949 ko00000,ko00001,ko00002,ko01000 - - - Trp_halogenase k141_5868_2 745310.G432_12125 2.39e-18 84.0 COG1609@1|root,COG1609@2|Bacteria,1MVUR@1224|Proteobacteria,2TUNV@28211|Alphaproteobacteria,2K2P2@204457|Sphingomonadales 204457|Sphingomonadales K helix_turn _helix lactose operon repressor - - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 k141_37702_1 1049564.TevJSym_af00640 1.37e-48 187.0 COG5183@1|root,COG5183@2|Bacteria,1PS4F@1224|Proteobacteria,1RZWB@1236|Gammaproteobacteria,1J519@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria A domain, Protein - - - - - - - - - - - - TSP_3 k141_37702_3 715451.ambt_09365 1.18e-39 138.0 COG3619@1|root,COG3619@2|Bacteria,1RB5Q@1224|Proteobacteria,1RRG5@1236|Gammaproteobacteria,466NN@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF1275) - - - - - - - - - - - - DUF1275 k141_2043_2 997296.PB1_12339 1.23e-29 116.0 COG0476@1|root,COG0476@2|Bacteria,1UZJC@1239|Firmicutes,4HB2K@91061|Bacilli,1ZBN2@1386|Bacillus 91061|Bacilli H bacteriocin maturation protein - - - - - - - - - - - - - k141_28124_1 218284.CCDN010000012_gene4435 5.94e-236 657.0 COG1686@1|root,COG1686@2|Bacteria,1TQN0@1239|Firmicutes,4HBD4@91061|Bacilli,1ZAS6@1386|Bacillus 91061|Bacilli M Belongs to the peptidase S11 family dacA GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0009002,GO:0016787,GO:0017171,GO:0019538,GO:0030312,GO:0043170,GO:0044238,GO:0044464,GO:0070008,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.16.4 ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - PBP5_C,Peptidase_S11 k141_10515_1 218284.CCDN010000001_gene6 2.69e-61 204.0 COG0550@1|root,COG0550@2|Bacteria,1TPUS@1239|Firmicutes,4HA6C@91061|Bacilli,1ZB7D@1386|Bacillus 91061|Bacilli L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topA - 5.99.1.2 ko:K03168 - - - - ko00000,ko01000,ko03032,ko03400 - - - Topoisom_bac,Toprim,zf-C4_Topoisom k141_24804_1 663321.REG_0156 6.24e-16 69.7 COG0257@1|root,COG0257@2|Bacteria,1NGEI@1224|Proteobacteria,1SGC9@1236|Gammaproteobacteria,282UF@191675|unclassified Enterobacteriaceae 1236|Gammaproteobacteria J Belongs to the bacterial ribosomal protein bL36 family rpmJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02919 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L36 k141_24804_4 1279017.AQYJ01000019_gene1466 6.48e-33 114.0 COG1841@1|root,COG1841@2|Bacteria,1N6ZE@1224|Proteobacteria,1SC8N@1236|Gammaproteobacteria,468BZ@72275|Alteromonadaceae 1236|Gammaproteobacteria J Ribosomal protein L30 rpmD GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02907 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L30 k141_22545_1 218284.CCDN010000008_gene4146 5.34e-144 419.0 COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HACS@91061|Bacilli,1ZB6H@1386|Bacillus 91061|Bacilli H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily menE - 6.2.1.26 ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R04030 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - AMP-binding,AMP-binding_C k141_35595_1 218284.CCDN010000001_gene1869 3.48e-114 331.0 COG2188@1|root,COG2188@2|Bacteria,1TQQQ@1239|Firmicutes,4H9TG@91061|Bacilli,1ZB5M@1386|Bacillus 91061|Bacilli K Transcriptional regulator ymfC - - ko:K03710 - - - - ko00000,ko03000 - - - GntR,UTRA k141_21064_1 1042377.AFPJ01000034_gene2427 5.85e-71 221.0 COG1028@1|root,COG1028@2|Bacteria,1RAEZ@1224|Proteobacteria,1S615@1236|Gammaproteobacteria,467FQ@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - - - - - - - - - - adh_short k141_17522_2 218284.CCDN010000006_gene3779 4.93e-77 236.0 COG4974@1|root,COG4974@2|Bacteria,1TQXV@1239|Firmicutes,4HFGC@91061|Bacilli,1ZFQ2@1386|Bacillus 91061|Bacilli L Belongs to the 'phage' integrase family - - - ko:K03733,ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase k141_2044_1 218284.CCDN010000007_gene3983 1.69e-89 271.0 COG0009@1|root,COG0009@2|Bacteria,1TP1I@1239|Firmicutes,4HA7W@91061|Bacilli,1ZB2V@1386|Bacillus 91061|Bacilli J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine ywlC GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87 ko:K07566 - - R10463 RC00745 ko00000,ko01000,ko03009,ko03016 - - - SUA5,Sua5_yciO_yrdC k141_5870_1 379066.GAU_2357 1.95e-51 188.0 COG0737@1|root,COG0737@2|Bacteria,1ZTEA@142182|Gemmatimonadetes 142182|Gemmatimonadetes F 5'-nucleotidase, C-terminal domain - - 3.1.3.5 ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - 5_nucleotid_C,Metallophos k141_4513_1 1042377.AFPJ01000052_gene1551 1.3e-39 144.0 COG3307@1|root,COG3307@2|Bacteria,1N225@1224|Proteobacteria,1RQWW@1236|Gammaproteobacteria,465GX@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG3307 Lipid A core - O-antigen ligase and related enzymes - - - - - - - - - - - - Wzy_C k141_34291_2 196490.AUEZ01000007_gene5152 1.33e-48 162.0 COG2370@1|root,COG2370@2|Bacteria,1N08F@1224|Proteobacteria,2UA0Y@28211|Alphaproteobacteria,3JW6Q@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O HupE / UreJ protein hupE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03192 - - - - ko00000 - - - HupE_UreJ k141_9511_1 1279017.AQYJ01000028_gene2076 1.75e-80 243.0 2B4XH@1|root,31XQC@2|Bacteria,1RHJF@1224|Proteobacteria,1S3S1@1236|Gammaproteobacteria,467JQ@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_9511_2 1279017.AQYJ01000028_gene2077 1.48e-95 288.0 COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,1RNMZ@1236|Gammaproteobacteria,4658H@72275|Alteromonadaceae 1236|Gammaproteobacteria H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein - - 2.7.1.180 ko:K03734 - - - - ko00000,ko01000 - - - ApbE k141_21065_1 1347369.CCAD010000043_gene974 3.17e-43 149.0 COG1309@1|root,COG1309@2|Bacteria,1V6CF@1239|Firmicutes,4HJIC@91061|Bacilli,1ZFKI@1386|Bacillus 91061|Bacilli K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N k141_35596_1 218284.CCDN010000001_gene1053 1.22e-73 225.0 COG1547@1|root,COG1547@2|Bacteria,1VBXA@1239|Firmicutes,4HMG9@91061|Bacilli,1ZH3U@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF309) ypuF - - ko:K09763 - - - - ko00000 - - - DUF309 k141_24805_1 218284.CCDN010000001_gene58 2.71e-180 532.0 COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,4HAEY@91061|Bacilli,1ZCEM@1386|Bacillus 91061|Bacilli F Belongs to the CarB family carB GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS k141_30447_2 218284.CCDN010000001_gene766 1.02e-102 306.0 COG0327@1|root,COG0327@2|Bacteria,1TQ27@1239|Firmicutes,4H9NY@91061|Bacilli,1ZAPV@1386|Bacillus 91061|Bacilli S Belongs to the GTP cyclohydrolase I type 2 NIF3 family yqfO GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - - - - - - - - - - NIF3 k141_4514_1 986075.CathTA2_1721 2.56e-17 82.4 COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,1TPYV@1239|Firmicutes,4HAB5@91061|Bacilli 91061|Bacilli E catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine yitJ - 1.5.1.20,2.1.1.10 ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 M00377 R00650,R01224,R07168 RC00003,RC00035,RC00081 ko00000,ko00001,ko00002,ko01000 - - - MTHFR,S-methyl_trans k141_26137_2 1174504.AJTN02000225_gene1877 3.59e-64 200.0 COG0757@1|root,COG0757@2|Bacteria,1V6E8@1239|Firmicutes,4HJ2V@91061|Bacilli,1ZG8H@1386|Bacillus 91061|Bacilli E Catalyzes a trans-dehydration via an enolate intermediate aroQ - 4.2.1.10 ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03084 RC00848 ko00000,ko00001,ko00002,ko01000 - - - DHquinase_II k141_11875_1 218284.CCDN010000001_gene1042 7.11e-32 120.0 COG1686@1|root,COG1686@2|Bacteria,1TQN0@1239|Firmicutes,4HBCE@91061|Bacilli,1ZB0W@1386|Bacillus 91061|Bacilli M Belongs to the peptidase S11 family dacF GO:0003674,GO:0003824,GO:0004175,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.16.4 ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - PBP5_C,Peptidase_S11 k141_4530_1 1384056.N787_04825 3.86e-91 281.0 COG0624@1|root,COG0624@2|Bacteria,1MW20@1224|Proteobacteria,1RPN7@1236|Gammaproteobacteria,1X4BQ@135614|Xanthomonadales 135614|Xanthomonadales E peptidase M20 - - - - - - - - - - - - M20_dimer,Peptidase_M20 k141_1162_1 221109.22778545 3.3e-172 493.0 COG2356@1|root,COG4085@1|root,COG2356@2|Bacteria,COG4085@2|Bacteria,1U9RR@1239|Firmicutes,4IJY3@91061|Bacilli,23MD1@182709|Oceanobacillus 91061|Bacilli L Endonuclease I - - - - - - - - - - - - Endonuclease_1 k141_10536_1 218284.CCDN010000011_gene4425 1.91e-130 381.0 COG2252@1|root,COG2252@2|Bacteria,1TQC6@1239|Firmicutes,4HANG@91061|Bacilli,1ZARH@1386|Bacillus 91061|Bacilli S permease pbuG - - ko:K06901 - - - - ko00000,ko02000 2.A.1.40 - iYO844.BSU06370 Xan_ur_permease k141_34307_1 42565.FP66_12170 7.21e-63 197.0 COG0692@1|root,COG0692@2|Bacteria,1MV80@1224|Proteobacteria,1RPDH@1236|Gammaproteobacteria,1XI06@135619|Oceanospirillales 135619|Oceanospirillales L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine ung - 3.2.2.27 ko:K03648 ko03410,ko05340,map03410,map05340 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG k141_34307_2 42565.FP66_12175 1.97e-95 281.0 COG0035@1|root,COG0035@2|Bacteria,1MV4N@1224|Proteobacteria,1RPBG@1236|Gammaproteobacteria,1XI9Z@135619|Oceanospirillales 135619|Oceanospirillales F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate upp - 2.4.2.9 ko:K00761 ko00240,ko01100,map00240,map01100 - R00966 RC00063 ko00000,ko00001,ko01000 - - - UPRTase k141_28150_1 218284.CCDN010000001_gene88 3.85e-90 278.0 COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,4H9T1@91061|Bacilli,1ZB77@1386|Bacillus 91061|Bacilli M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan murE GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 ko:K01928 ko00300,ko00550,map00300,map00550 - R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M k141_13033_1 218284.CCDN010000001_gene1353 7.7e-117 348.0 COG0619@1|root,COG0619@2|Bacteria,1VBW7@1239|Firmicutes,4HB6S@91061|Bacilli,1ZS19@1386|Bacillus 91061|Bacilli P Spore gernimation protein GerA gerAA_2 - - - - - - - - - - - GerA k141_22585_1 1307436.PBF_21838 8.76e-191 535.0 COG0533@1|root,COG0533@2|Bacteria,1TQDR@1239|Firmicutes,4HANB@91061|Bacilli,1ZBT3@1386|Bacillus 91061|Bacilli O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction tsaD GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 ko:K01409 - - R10648 RC00070,RC00416 ko00000,ko01000,ko03016 - - - Peptidase_M22 k141_22585_2 1294265.JCM21738_5447 2.62e-98 286.0 COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,4HIKU@91061|Bacilli,1ZGAT@1386|Bacillus 91061|Bacilli K This enzyme acetylates the N-terminal alanine of ribosomal protein S18 rimI - 2.3.1.128 ko:K03789 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_1 k141_31607_1 1134413.ANNK01000161_gene3581 6.86e-05 43.9 COG0217@1|root,COG0217@2|Bacteria,1TPP5@1239|Firmicutes,4H9WJ@91061|Bacilli,1ZBN0@1386|Bacillus 91061|Bacilli K transcriptional regulatory protein yeeN GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - - - - - - - - - - Transcrip_reg k141_31607_2 1121289.JHVL01000006_gene2828 1.26e-65 207.0 COG3650@1|root,COG3650@2|Bacteria,1V96I@1239|Firmicutes,24HFD@186801|Clostridia,36J0F@31979|Clostridiaceae 186801|Clostridia S response to hydrogen peroxide - - - - - - - - - - - - - k141_2076_2 218284.CCDN010000003_gene2987 5.38e-123 351.0 COG0193@1|root,COG0193@2|Bacteria,1V3NB@1239|Firmicutes,4HH2Z@91061|Bacilli,1ZC7I@1386|Bacillus 91061|Bacilli J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis pth GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 ko:K01056 - - - - ko00000,ko01000,ko03012 - - - Pept_tRNA_hydro k141_29552_1 1196031.ALEG01000064_gene3635 9.24e-144 422.0 COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,4HABZ@91061|Bacilli,1ZB5W@1386|Bacillus 91061|Bacilli J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) thrS GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD k141_5917_1 1294265.JCM21738_2683 2.34e-86 254.0 COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HB3V@91061|Bacilli,1ZMXA@1386|Bacillus 91061|Bacilli IQ AMP-binding enzyme C-terminal domain - - - ko:K00666 - - - - ko00000,ko01000,ko01004 - - - AMP-binding,AMP-binding_C k141_3307_1 500633.CLOHIR_01877 3.38e-74 245.0 COG1048@1|root,COG1048@2|Bacteria,1VTMM@1239|Firmicutes,25HJM@186801|Clostridia,25SZA@186804|Peptostreptococcaceae 186801|Clostridia C aconitate hydratase acnA - 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_C k141_33036_1 589873.EP13_14270 1.58e-87 269.0 COG2942@1|root,COG2942@2|Bacteria,1MX1J@1224|Proteobacteria,1RSCF@1236|Gammaproteobacteria,465YE@72275|Alteromonadaceae 1236|Gammaproteobacteria G N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) yihS GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006066,GO:0006082,GO:0006790,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016853,GO:0016860,GO:0016861,GO:0019637,GO:0034308,GO:0042180,GO:0042802,GO:0044237,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0050089,GO:0061593,GO:0061720,GO:0071704,GO:1901135,GO:1901136,GO:1901575,GO:1901615,GO:1902776,GO:1902777 5.3.1.31 ko:K18479 - - R10765 RC00376 ko00000,ko01000 - - - GlcNAc_2-epim k141_22586_1 218284.CCDN010000001_gene1375 2.56e-61 204.0 COG1120@1|root,COG1120@2|Bacteria,1TP2Q@1239|Firmicutes,4HA28@91061|Bacilli,1ZASR@1386|Bacillus 91061|Bacilli HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components yvrA - 3.6.3.34 ko:K02013 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 - - ABC_tran,CbiZ k141_1165_1 1196031.ALEG01000068_gene4834 2.1e-61 203.0 COG0119@1|root,COG0119@2|Bacteria,1TP4Y@1239|Firmicutes,4HA6E@91061|Bacilli,1ZC5T@1386|Bacillus 91061|Bacilli E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) leuA - 2.3.3.13 ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 M00432 R01213 RC00004,RC00470,RC02754 br01601,ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS10690,iYO844.BSU28280 HMGL-like,LeuA_dimer k141_17560_1 292.DM42_5396 3.03e-77 239.0 COG0693@1|root,COG0693@2|Bacteria,1MVTT@1224|Proteobacteria,2VKUH@28216|Betaproteobacteria,1K23D@119060|Burkholderiaceae 28216|Betaproteobacteria S PFAM ThiJ PfpI domain protein - - - - - - - - - - - - DJ-1_PfpI k141_34309_2 1158604.I591_01278 0.00014 48.9 2BN8E@1|root,32GVV@2|Bacteria,1U0F5@1239|Firmicutes,4I9SP@91061|Bacilli,4B4NT@81852|Enterococcaceae 91061|Bacilli - - - - - - - - - - - - - - - k141_22587_1 218284.CCDN010000002_gene2740 4.09e-10 60.1 COG1404@1|root,COG1404@2|Bacteria,1TQRU@1239|Firmicutes,4HAZA@91061|Bacilli,1ZAZK@1386|Bacillus 91061|Bacilli O Belongs to the peptidase S8 family - - - ko:K17734 - - - - ko00000,ko01000,ko01002 - - - Inhibitor_I9,PA,PPC,Peptidase_S8,SLH k141_5919_2 1042377.AFPJ01000008_gene1958 8.12e-39 139.0 COG2850@1|root,COG2850@2|Bacteria,1MUAC@1224|Proteobacteria,1RQQP@1236|Gammaproteobacteria,465RI@72275|Alteromonadaceae 1236|Gammaproteobacteria S Cupin-like domain - - - - - - - - - - - - Cupin_8 k141_10677_1 1042377.AFPJ01000030_gene501 4.03e-110 333.0 COG0129@1|root,COG0129@2|Bacteria,1MU3T@1224|Proteobacteria,1RMNA@1236|Gammaproteobacteria,464QM@72275|Alteromonadaceae 1236|Gammaproteobacteria EG Belongs to the IlvD Edd family edd GO:0003674,GO:0003824,GO:0004456,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019520,GO:0019521,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0046176,GO:0046177,GO:0046395,GO:0071704,GO:0072329,GO:1901575 4.2.1.12 ko:K01690 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 M00008 R02036 RC00543 ko00000,ko00001,ko00002,ko01000 - - iEcolC_1368.EcolC_1781,iJN746.PP_1010,iPC815.YPO2533,iYL1228.KPN_02366 ILVD_EDD k141_10677_2 1453501.JELR01000002_gene197 4.71e-77 244.0 COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,1RNIT@1236|Gammaproteobacteria,464TD@72275|Alteromonadaceae 1236|Gammaproteobacteria G Belongs to the GPI family pgi GO:0003674,GO:0003824,GO:0004347,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033554,GO:0034404,GO:0034599,GO:0034641,GO:0034654,GO:0034655,GO:0042221,GO:0042802,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0055086,GO:0070887,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 - - iEcSMS35_1347.EcSMS35_4486 PGI k141_36575_1 1123073.KB899241_gene2116 1.94e-44 159.0 COG1228@1|root,COG1228@2|Bacteria,1R6NP@1224|Proteobacteria,1SZBD@1236|Gammaproteobacteria,1X5QW@135614|Xanthomonadales 135614|Xanthomonadales Q Amidohydrolase family - - - - - - - - - - - - Amidohydro_1 k141_17750_1 1123236.KB899388_gene2033 4.64e-99 300.0 COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,1RNMP@1236|Gammaproteobacteria,465JQ@72275|Alteromonadaceae 1236|Gammaproteobacteria G Synthesizes alpha-1,4-glucan chains using ADP-glucose glgA GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 M00565 R02421 RC00005 ko00000,ko00001,ko00002,ko01000,ko01003 - GT5 - Glyco_transf_5,Glycos_transf_1 k141_8081_2 986075.CathTA2_1658 2.45e-95 288.0 COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,4HA4E@91061|Bacilli 91061|Bacilli P Belongs to the ABC transporter superfamily - - - - - - - - - - - - ABC_tran,oligo_HPY k141_16574_2 1116375.VEJY3_06890 3.27e-148 418.0 COG0830@1|root,COG0830@2|Bacteria,1MW8Q@1224|Proteobacteria,1RP91@1236|Gammaproteobacteria,1XUQQ@135623|Vibrionales 135623|Vibrionales O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter ureF - - ko:K03188 - - - - ko00000 - - - UreF k141_16574_3 1116375.VEJY3_06895 6.4e-147 414.0 COG0378@1|root,COG0378@2|Bacteria,1MVBD@1224|Proteobacteria,1RP5R@1236|Gammaproteobacteria,1XSZB@135623|Vibrionales 135623|Vibrionales KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG - - - ko:K03189 - - - - ko00000 - - - cobW k141_16574_4 1116375.VEJY3_06900 1.31e-89 266.0 COG2370@1|root,COG2370@2|Bacteria 2|Bacteria O cobalamin-transporting ATPase activity ureJ - - ko:K03192 - - - - ko00000 - - - HupE_UreJ k141_16574_5 223926.28806362 6.36e-37 135.0 COG0471@1|root,COG0471@2|Bacteria,1R6QF@1224|Proteobacteria,1RQIG@1236|Gammaproteobacteria,1XTZX@135623|Vibrionales 135623|Vibrionales P COG0471 Di- and tricarboxylate transporters - - - ko:K14445 - - - - ko00000,ko02000 2.A.47.1 - - Na_sulph_symp k141_3456_1 1117379.BABA_09861 1.39e-53 191.0 COG2909@1|root,COG3629@1|root,COG2909@2|Bacteria,COG3629@2|Bacteria,1UWHI@1239|Firmicutes,4HADH@91061|Bacilli,1ZE89@1386|Bacillus 91061|Bacilli KT COG2909 ATP-dependent transcriptional regulator - - - ko:K03556 - - - - ko00000,ko03000 - - - AAA_16,BTAD,TPR_12,TPR_8 k141_28285_1 218284.CCDN010000001_gene1281 8.67e-154 444.0 COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,4HB31@91061|Bacilli,1ZARE@1386|Bacillus 91061|Bacilli EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia trpE GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.1.3.27 ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Anth_synt_I_N,Chorismate_bind k141_30564_1 1380394.JADL01000011_gene3977 5.94e-40 151.0 COG0404@1|root,COG0446@1|root,COG0404@2|Bacteria,COG0446@2|Bacteria,1MVEK@1224|Proteobacteria,2TTD7@28211|Alphaproteobacteria,2JR1W@204441|Rhodospirillales 204441|Rhodospirillales E 2Fe-2S iron-sulfur cluster binding domain - - 1.5.99.5 ko:K22086 ko00680,ko01120,map00680,map01120 - R00609 RC00190,RC00557 ko00000,ko00001,ko01000 - - - FAD_oxidored,Fer2_4,GCV_T,GCV_T_C,Pyr_redox_2 k141_21249_1 1453501.JELR01000002_gene1494 6.41e-96 286.0 COG3672@1|root,COG3672@2|Bacteria,1RKG9@1224|Proteobacteria,1S8MS@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Periplasmic Protein - - - - - - - - - - - - Transglut_core k141_30565_1 888055.HMPREF9015_01920 1.03e-73 234.0 COG1783@1|root,COG1783@2|Bacteria,3797J@32066|Fusobacteria 32066|Fusobacteria S Phage terminase, large subunit, PBSX family - - - - - - - - - - - - Terminase_3,Terminase_3C k141_15268_1 1117647.M5M_09020 8.91e-111 344.0 COG3118@1|root,COG3118@2|Bacteria,1QWQK@1224|Proteobacteria,1T5NR@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Sulfotransferase domain - - - - - - - - - - - - Sulfotransfer_3 k141_15268_2 1134474.O59_004229 1.22e-31 116.0 2ANPA@1|root,31DNS@2|Bacteria,1RHTE@1224|Proteobacteria,1S78C@1236|Gammaproteobacteria,1FIF6@10|Cellvibrio 1236|Gammaproteobacteria S Protein of unknown function (DUF3833) PP2730 - - - - - - - - - - - DUF3833 k141_36577_1 42565.FP66_01065 3.06e-161 462.0 COG1012@1|root,COG1012@2|Bacteria,1MV2I@1224|Proteobacteria,1RPQW@1236|Gammaproteobacteria,1XHCT@135619|Oceanospirillales 135619|Oceanospirillales C Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate astD - 1.2.1.71 ko:K06447 ko00330,ko01100,map00330,map01100 - R05049 RC00080 ko00000,ko00001,ko01000 - - - Aldedh k141_17752_1 218284.CCDN010000005_gene3222 2.17e-93 275.0 COG0681@1|root,COG0681@2|Bacteria,1V2BJ@1239|Firmicutes,4HGCB@91061|Bacilli,1ZAPC@1386|Bacillus 91061|Bacilli U Belongs to the peptidase S26 family spsB - 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24 k141_36601_2 218284.CCDN010000001_gene1704 1.95e-45 151.0 COG0778@1|root,COG0778@2|Bacteria,1UYJU@1239|Firmicutes,4HBVQ@91061|Bacilli,1ZAQV@1386|Bacillus 91061|Bacilli C nitroreductase ydgI - - - - - - - - - - - Nitroreductase k141_33216_1 1385517.N800_08280 4.1e-56 197.0 COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,1RN5I@1236|Gammaproteobacteria,1X3SP@135614|Xanthomonadales 135614|Xanthomonadales C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate acnA - 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_C k141_16602_1 218284.CCDN010000001_gene1363 2.07e-87 263.0 COG0428@1|root,COG0428@2|Bacteria,1V1UC@1239|Firmicutes,4HGST@91061|Bacilli,1ZCIQ@1386|Bacillus 91061|Bacilli P transporter - - - ko:K07238 - - - - ko00000,ko02000 2.A.5.5 - - Zip k141_10697_1 218284.CCDN010000005_gene3403 2.12e-132 379.0 2B51H@1|root,31XUS@2|Bacteria,1V6KA@1239|Firmicutes,4HKBP@91061|Bacilli,1ZFY9@1386|Bacillus 91061|Bacilli S Sporulation protein YunB (Spo_YunB) yunB - - - - - - - - - - - Spore_YunB k141_10697_2 218284.CCDN010000005_gene3402 4.28e-78 241.0 COG2206@1|root,COG2206@2|Bacteria,1TQIM@1239|Firmicutes,4HBV6@91061|Bacilli,1ZCMY@1386|Bacillus 91061|Bacilli T HD domain cnpD3 - - - - - - - - - - - HD,HD_5 k141_21294_3 40571.JOEA01000003_gene3775 0.000851 45.8 COG1231@1|root,COG1231@2|Bacteria,2GK23@201174|Actinobacteria,4E34P@85010|Pseudonocardiales 201174|Actinobacteria E Flavin containing amine oxidoreductase - - 1.4.3.4 ko:K00274 ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034 M00135 R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354 RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713 ko00000,ko00001,ko00002,ko01000 - - - Amino_oxidase k141_15290_2 1123020.AUIE01000008_gene3689 1.03e-192 544.0 COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,1RMVU@1236|Gammaproteobacteria,1YDZX@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria C Iron-containing alcohol dehydrogenase - - 1.1.1.1 ko:K00001,ko:K00100 ko00010,ko00071,ko00350,ko00625,ko00626,ko00650,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00650,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R03544,R03545,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - Fe-ADH k141_15290_3 1279017.AQYJ01000024_gene896 1.08e-37 131.0 COG0225@1|root,COG0225@2|Bacteria,1R33Z@1224|Proteobacteria,1T62V@1236|Gammaproteobacteria,46DFA@72275|Alteromonadaceae 1236|Gammaproteobacteria O Peptide methionine sulfoxide reductase msrA2 - 1.8.4.11 ko:K07304 - - - - ko00000,ko01000 - - - PMSR k141_2284_1 441769.ABFU01000057_gene808 2.36e-156 459.0 COG1033@1|root,COG1033@2|Bacteria,1VSWA@1239|Firmicutes,4HBIV@91061|Bacilli 91061|Bacilli S MMPL family ydfJ - - ko:K07003 - - - - ko00000 - - - MMPL k141_16603_1 218284.CCDN010000001_gene1102 1.7e-167 475.0 COG0240@1|root,COG0240@2|Bacteria,1TQ5P@1239|Firmicutes,4HAXW@91061|Bacilli,1ZCHQ@1386|Bacillus 91061|Bacilli I Glycerol-3-phosphate dehydrogenase gpsA GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0047952,GO:0055114 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 - R00842,R00844 RC00029 ko00000,ko00001,ko01000 - - - NAD_Gly3P_dh_C,NAD_Gly3P_dh_N k141_30602_1 1279017.AQYJ01000028_gene2321 3.12e-57 208.0 COG2982@1|root,COG2982@2|Bacteria,1MUME@1224|Proteobacteria,1RNPC@1236|Gammaproteobacteria,464KK@72275|Alteromonadaceae 1236|Gammaproteobacteria M Domain of Unknown Function (DUF748) - - - - - - - - - - - - DUF748,OmpA k141_8114_1 218284.CCDN010000002_gene2160 1.88e-105 311.0 COG0395@1|root,COG0395@2|Bacteria,1TQG0@1239|Firmicutes,4HD6Q@91061|Bacilli,1ZAVF@1386|Bacillus 91061|Bacilli P PFAM binding-protein-dependent transport systems inner membrane component - - - ko:K02026 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - BPD_transp_1 k141_2285_1 1294265.JCM21738_1169 1.92e-32 115.0 2EUDS@1|root,33MW4@2|Bacteria,1VHIA@1239|Firmicutes,4HSFG@91061|Bacilli,1ZEP8@1386|Bacillus 91061|Bacilli S Sporulation inhibitor of replication protein sirA yneE - - - - - - - - - - - SirA k141_2285_2 1294265.JCM21738_1170 2.23e-25 99.0 COG1182@1|root,COG1182@2|Bacteria,1UZBY@1239|Firmicutes,4HB1Z@91061|Bacilli,1ZD4D@1386|Bacillus 91061|Bacilli I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity azoR - - ko:K01118 - - - - ko00000,ko01000 - - - Flavodoxin_2 k141_37916_1 856793.MICA_654 4.54e-70 238.0 COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,2TRBQ@28211|Alphaproteobacteria,4BPPZ@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria C Dehydrogenase E1 component sucA - 1.2.4.2 ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R00621,R01933,R01940,R03316,R08549 RC00004,RC00027,RC00627,RC02743,RC02833,RC02883 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr k141_16605_1 1117379.BABA_25521 1.33e-96 304.0 COG4412@1|root,COG4412@2|Bacteria,1U02W@1239|Firmicutes,4HJCX@91061|Bacilli,1ZC0P@1386|Bacillus 91061|Bacilli V Peptidase M6 - - - ko:K09607 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M6 k141_37917_1 1121938.AUDY01000009_gene2101 1.02e-72 223.0 COG0176@1|root,COG0176@2|Bacteria,1TP4Q@1239|Firmicutes,4HA8G@91061|Bacilli,3NDIV@45667|Halobacillus 91061|Bacilli G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway tal GO:0003674,GO:0005488,GO:0005515,GO:0042802 2.2.1.2 ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01827 RC00439,RC00604 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU37110 TAL_FSA k141_34466_2 246200.SPO1047 8.46e-81 255.0 COG3344@1|root,COG3344@2|Bacteria,1R44F@1224|Proteobacteria,2U6GB@28211|Alphaproteobacteria,4NDKE@97050|Ruegeria 28211|Alphaproteobacteria L Reverse transcriptase (RNA-dependent DNA polymerase) - - - - - - - - - - - - RVT_1 k141_28334_1 1280001.BAOA01000075_gene3199 1.51e-159 462.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1SYIV@1236|Gammaproteobacteria,1Y2T1@135623|Vibrionales 135623|Vibrionales NT methyl-accepting chemotaxis protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - MCPsignal k141_28334_2 1219076.N646_4231 6.05e-145 410.0 COG0637@1|root,COG0637@2|Bacteria,1NSPA@1224|Proteobacteria,1RQET@1236|Gammaproteobacteria,1XWG8@135623|Vibrionales 135623|Vibrionales S phosphatase phosphohexomutase - - - - - - - - - - - - HAD_2 k141_28334_3 223926.28809073 1.03e-78 238.0 2AXJM@1|root,31PJR@2|Bacteria,1QJUS@1224|Proteobacteria,1THW8@1236|Gammaproteobacteria,1XXQC@135623|Vibrionales 135623|Vibrionales - - VV20220 - - - - - - - - - - - - k141_28334_4 28229.ND2E_3303 6.5e-79 238.0 COG3045@1|root,COG3045@2|Bacteria,1RDI5@1224|Proteobacteria,1T060@1236|Gammaproteobacteria,2Q82C@267889|Colwelliaceae 1236|Gammaproteobacteria S CreA protein creA - - ko:K05805 - - - - ko00000 - - - CreA k141_28334_5 1280001.BAOA01000075_gene3204 6.04e-251 692.0 COG0524@1|root,COG0524@2|Bacteria,1MUUC@1224|Proteobacteria,1RMN2@1236|Gammaproteobacteria,1XT8M@135623|Vibrionales 135623|Vibrionales G COG0524 Sugar kinases, ribokinase family - - 2.7.1.73 ko:K00892 ko00230,map00230 - R01131,R01228 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB k141_16606_1 1423321.AS29_16010 4.85e-120 349.0 COG0115@1|root,COG0115@2|Bacteria,1TPY2@1239|Firmicutes,4HC7T@91061|Bacilli,1ZQE0@1386|Bacillus 91061|Bacilli E Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family ilvE - 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_4 k141_8116_1 1294265.JCM21738_1299 6.46e-166 476.0 COG0697@1|root,COG0697@2|Bacteria,1TP7K@1239|Firmicutes,4HAH1@91061|Bacilli,1ZBEF@1386|Bacillus 91061|Bacilli EG Spore germination protein gerKA - - ko:K06295,ko:K06307 - - - - ko00000 - - - GerA k141_4678_1 1078085.HMPREF1210_00657 2.3e-39 153.0 COG1404@1|root,COG2755@1|root,COG1404@2|Bacteria,COG2755@2|Bacteria,1TPH1@1239|Firmicutes,4HBQH@91061|Bacilli 91061|Bacilli O Belongs to the peptidase S8 family prtS - 3.4.21.110,3.4.21.96 ko:K01361,ko:K08652 - - - - ko00000,ko01000,ko01002,ko03110 - - - FIVAR,Gram_pos_anchor,Inhibitor_I9,PA,Peptidase_S8,SLH,YSIRK_signal,fn3_5 k141_30604_2 1453501.JELR01000001_gene3262 4.08e-60 200.0 COG0810@1|root,COG0810@2|Bacteria,1PEER@1224|Proteobacteria,1RPPU@1236|Gammaproteobacteria,466NW@72275|Alteromonadaceae 1236|Gammaproteobacteria M Chalcone isomerase-like - - - ko:K03832 - - - - ko00000,ko02000 2.C.1.1 - - Chalcone_3,TonB_2,TonB_C k141_28335_1 1453501.JELR01000001_gene1978 8.16e-105 318.0 COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,1RMMD@1236|Gammaproteobacteria,464BS@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the oxidation of L-aspartate to iminoaspartate nadB GO:0000166,GO:0001716,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008734,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0015922,GO:0016491,GO:0016638,GO:0016641,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044318,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.4.3.16 ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 M00115 R00357,R00481 RC00006,RC02566 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b2574,iBWG_1329.BWG_2338,iECDH10B_1368.ECDH10B_2742,iECDH1ME8569_1439.ECDH1ME8569_2501,iETEC_1333.ETEC_2787,iEcDH1_1363.EcDH1_1094,iJO1366.b2574,iJR904.b2574,iLF82_1304.LF82_1433,iNRG857_1313.NRG857_12785,iY75_1357.Y75_RS13445,iYL1228.KPN_02899 FAD_binding_2,Succ_DH_flav_C k141_34467_1 1120972.AUMH01000053_gene1764 1.85e-23 105.0 COG2801@1|root,COG2801@2|Bacteria,1TQH6@1239|Firmicutes,4HHM8@91061|Bacilli 91061|Bacilli L PFAM Mu transposase, C-terminal - - - - - - - - - - - - Mu-transpos_C,rve k141_21297_1 225849.swp_1628 4.08e-109 321.0 COG1262@1|root,COG1262@2|Bacteria,1RB2U@1224|Proteobacteria,1S3D5@1236|Gammaproteobacteria,2QBGH@267890|Shewanellaceae 1236|Gammaproteobacteria S SapC - - - - - - - - - - - - SapC k141_21297_2 1453501.JELR01000005_gene1579 4.69e-134 391.0 COG2850@1|root,COG2850@2|Bacteria,1MUAC@1224|Proteobacteria,1RQQP@1236|Gammaproteobacteria,465RI@72275|Alteromonadaceae 1236|Gammaproteobacteria S Cupin-like domain - - - - - - - - - - - - Cupin_8 k141_4679_1 1078085.HMPREF1210_01692 3.06e-82 272.0 COG0366@1|root,COG1523@1|root,COG3210@1|root,COG5492@1|root,COG0366@2|Bacteria,COG1523@2|Bacteria,COG3210@2|Bacteria,COG5492@2|Bacteria,1TP3M@1239|Firmicutes,4HBP5@91061|Bacilli,26GQX@186818|Planococcaceae 91061|Bacilli GN Carbohydrate-binding module 48 (Isoamylase N-terminal domain) pulA2 - 3.2.1.1,3.2.1.41 ko:K01176,ko:K01200 ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973 - R02108,R02111,R02112,R11262 - ko00000,ko00001,ko01000 - CBM48,GH13 - Alpha-amylase,Big_2,CBM_48,G5,Gram_pos_anchor,PUD,SLH,YSIRK_signal k141_8117_2 1479239.JQMU01000001_gene1898 8.07e-07 53.1 COG4772@1|root,COG4772@2|Bacteria,1MWDG@1224|Proteobacteria,2U4AH@28211|Alphaproteobacteria,2K4W5@204457|Sphingomonadales 204457|Sphingomonadales P TonB dependent receptor - - - ko:K16091 - - - - ko00000,ko02000 1.B.14.1.14 - - Plug,TonB_dep_Rec k141_28336_1 1453501.JELR01000001_gene3271 3.4e-105 313.0 COG2267@1|root,COG2267@2|Bacteria,1R41P@1224|Proteobacteria,1T1IM@1236|Gammaproteobacteria,467KZ@72275|Alteromonadaceae 1236|Gammaproteobacteria I Serine aminopeptidase, S33 - - - - - - - - - - - - Abhydrolase_1 k141_37919_1 1279017.AQYJ01000028_gene2175 5.84e-79 250.0 COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,1RQR7@1236|Gammaproteobacteria,4668G@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria ycbB GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0006508,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0008236,GO:0008238,GO:0009273,GO:0009987,GO:0016740,GO:0016746,GO:0016755,GO:0016787,GO:0016807,GO:0017171,GO:0019538,GO:0033554,GO:0042546,GO:0043164,GO:0043170,GO:0044036,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0050896,GO:0051716,GO:0070004,GO:0070008,GO:0070011,GO:0071554,GO:0071704,GO:0071840,GO:0071972,GO:0140096,GO:1901564 - ko:K21470 - - - - ko00000,ko01002,ko01011 - - - PG_binding_1,YkuD k141_8118_1 1294265.JCM21738_161 9.67e-122 358.0 COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H9SA@91061|Bacilli,1ZAXY@1386|Bacillus 91061|Bacilli M penicillin-binding protein ponA GO:0005575,GO:0005576 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase,fn3 k141_16609_1 218284.CCDN010000007_gene3837 2.42e-108 320.0 COG0673@1|root,COG0673@2|Bacteria,1USVA@1239|Firmicutes,4HDVM@91061|Bacilli,1ZQBZ@1386|Bacillus 91061|Bacilli S Oxidoreductase family, NAD-binding Rossmann fold - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C k141_17803_1 314275.MADE_1018485 5.28e-95 299.0 COG4774@1|root,COG4774@2|Bacteria,1MV0X@1224|Proteobacteria,1RN3C@1236|Gammaproteobacteria,464QQ@72275|Alteromonadaceae 1236|Gammaproteobacteria P TonB dependent receptor - - - ko:K16090 - - - - ko00000,ko02000 1.B.14.1.11 - - Plug,TonB_dep_Rec k141_30605_1 1462527.CCDM010000001_gene3179 9.61e-09 55.5 COG0510@1|root,COG0510@2|Bacteria,1TQW6@1239|Firmicutes,4HC1S@91061|Bacilli,23KKW@182709|Oceanobacillus 91061|Bacilli M RIO1 family - - - - - - - - - - - - APH k141_30605_2 406124.ACPC01000049_gene139 5.96e-69 212.0 COG1670@1|root,COG1670@2|Bacteria,1VAQC@1239|Firmicutes,4HN5K@91061|Bacilli,1ZQA1@1386|Bacillus 91061|Bacilli J Acetyltransferase (GNAT) domain - - 2.3.1.128 ko:K03789 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_1,Acetyltransf_10,Acetyltransf_3,Acetyltransf_4 k141_21300_1 218284.CCDN010000006_gene3537 1.25e-146 416.0 COG1834@1|root,COG1834@2|Bacteria,1VDT8@1239|Firmicutes,4ISAW@91061|Bacilli,1ZCTN@1386|Bacillus 91061|Bacilli E Amidinotransferase ykgA - - - - - - - - - - - Amidinotransf k141_28338_1 218284.CCDN010000001_gene1331 4.82e-154 441.0 COG0508@1|root,COG0508@2|Bacteria,1TP3C@1239|Firmicutes,4HBVM@91061|Bacilli,1ZBCB@1386|Bacillus 91061|Bacilli C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) odhB - 2.3.1.61 ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R02570,R02571,R08549 RC00004,RC02727,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding k141_33219_3 1042377.AFPJ01000010_gene1448 4.03e-249 687.0 COG3007@1|root,COG3007@2|Bacteria,1MWCQ@1224|Proteobacteria,1RPPP@1236|Gammaproteobacteria,4657U@72275|Alteromonadaceae 1236|Gammaproteobacteria I Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP) fabV GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.3.1.44,1.3.1.9 ko:K00209 ko00061,ko00650,ko01100,ko01120,ko01200,ko01212,map00061,map00650,map01100,map01120,map01200,map01212 M00083 R01171,R04429,R04724,R04955,R04958,R04961,R04966,R04969 RC00052,RC00076 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Eno-Rase_FAD_bd,Eno-Rase_NADH_b,Enoyl_reductase k141_36602_1 223926.28806603 4.1e-187 530.0 COG0144@1|root,COG3270@1|root,COG0144@2|Bacteria,COG3270@2|Bacteria,1NAY1@1224|Proteobacteria,1RP74@1236|Gammaproteobacteria,1XSE4@135623|Vibrionales 135623|Vibrionales J Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA rsmF GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.178 ko:K11392 - - - - ko00000,ko01000,ko03009 - - - Methyltr_RsmB-F,Methyltr_RsmF_N,Methyltranf_PUA k141_36602_2 1116375.VEJY3_07655 2.69e-189 526.0 COG2996@1|root,COG2996@2|Bacteria,1MXC3@1224|Proteobacteria,1RS4D@1236|Gammaproteobacteria,1XTG1@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria - - - ko:K00243 - - - - ko00000 - - - S1_2 k141_36602_3 1219076.N646_0640 2.9e-294 806.0 2CG2X@1|root,2Z7NT@2|Bacteria,1MW33@1224|Proteobacteria,1RQZI@1236|Gammaproteobacteria,1XSII@135623|Vibrionales 135623|Vibrionales - - VP1614 - - - - - - - - - - - - k141_36602_4 1116375.VEJY3_07665 1.36e-104 303.0 COG2050@1|root,COG2050@2|Bacteria,1RKGI@1224|Proteobacteria,1S6IX@1236|Gammaproteobacteria,1XX0B@135623|Vibrionales 135623|Vibrionales Q Domain of unknown function (DUF4442) - - - - - - - - - - - - DUF4442 k141_8119_1 218284.CCDN010000006_gene3535 1.98e-23 90.1 2E5UW@1|root,330J3@2|Bacteria,1VFMQ@1239|Firmicutes,4HPRZ@91061|Bacilli,1ZIYY@1386|Bacillus 91061|Bacilli S Small acid-soluble spore protein H family sspH - - ko:K06425 - - - - ko00000 - - - SspH k141_15292_2 1453501.JELR01000001_gene2477 1.45e-63 209.0 2EC19@1|root,3360G@2|Bacteria,1N87W@1224|Proteobacteria,1S7E3@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Peptidoglycan-binding protein, CsiV pgs1 - - - - - - - - - - - CsiV k141_2286_2 1348635.BBJY01000003_gene3776 4.58e-250 689.0 COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,1RM9E@1236|Gammaproteobacteria,1XSE0@135623|Vibrionales 135623|Vibrionales P Belongs to the ABC transporter superfamily - - - ko:K10112 ko02010,map02010 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1 - - ABC_tran,TOBE_2 k141_2286_3 1348635.BBJY01000003_gene3777 5.48e-204 565.0 COG0395@1|root,COG0395@2|Bacteria,1QQJS@1224|Proteobacteria,1RR8Z@1236|Gammaproteobacteria,1XTDN@135623|Vibrionales 135623|Vibrionales P PFAM binding-protein-dependent transport systems inner membrane component - - - - - - - - - - - - BPD_transp_1 k141_2286_4 1348635.BBJY01000003_gene3778 1.8e-183 513.0 COG1175@1|root,COG1175@2|Bacteria,1MVAP@1224|Proteobacteria,1RYI1@1236|Gammaproteobacteria,1Y25Z@135623|Vibrionales 135623|Vibrionales G Binding-protein-dependent transport system inner membrane component - - - - - - - - - - - - BPD_transp_1 k141_34470_1 55601.VANGNB10_cI1793c 6.04e-20 87.4 COG0583@1|root,COG0583@2|Bacteria,1MW1R@1224|Proteobacteria,1RQMP@1236|Gammaproteobacteria,1XUU4@135623|Vibrionales 135623|Vibrionales K Transcriptional regulator, LysR family - - - - - - - - - - - - HTH_1,LysR_substrate k141_17805_2 1033738.CAEP01000137_gene1516 6.06e-15 80.9 COG1467@1|root,COG1467@2|Bacteria,1VHYM@1239|Firmicutes,4HNRP@91061|Bacilli 91061|Bacilli L DNA primase activity - - - - - - - - - - - - PriCT_1 k141_4682_1 218284.CCDN010000001_gene1294 2.07e-85 260.0 COG0053@1|root,COG0053@2|Bacteria,1TP5C@1239|Firmicutes,4HAP0@91061|Bacilli,1ZBSN@1386|Bacillus 91061|Bacilli P Dimerisation domain of Zinc Transporter cat - - - - - - - - - - - Cation_efflux,ZT_dimer k141_15320_1 1219076.N646_4717 3.05e-109 333.0 COG0601@1|root,COG1173@1|root,COG0601@2|Bacteria,COG1173@2|Bacteria,1R3VQ@1224|Proteobacteria,1RY4F@1236|Gammaproteobacteria,1XTGP@135623|Vibrionales 135623|Vibrionales P Binding-protein-dependent transport system inner membrane component - - - ko:K02033,ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 k141_31771_1 218284.CCDN010000002_gene2761 9.09e-23 94.7 COG0775@1|root,COG0775@2|Bacteria,1TSB7@1239|Firmicutes,4HDEM@91061|Bacilli,1ZAYM@1386|Bacillus 91061|Bacilli F Phosphorylase superfamily - - 3.2.2.9 ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 M00034,M00609 R00194,R01401 RC00063,RC00318 ko00000,ko00001,ko00002,ko01000 - - - Cu_amine_oxidN1,PNP_UDP_1 k141_4743_1 218284.CCDN010000005_gene3284 4.57e-113 330.0 COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,4H9YB@91061|Bacilli,1ZBA4@1386|Bacillus 91061|Bacilli E Belongs to the ABC transporter superfamily oppF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY k141_3532_1 1408433.JHXV01000012_gene3999 4.68e-06 51.6 COG2885@1|root,COG2885@2|Bacteria,4NE8J@976|Bacteroidetes,1HY0A@117743|Flavobacteriia 976|Bacteroidetes M Belongs to the ompA family - - - - - - - - - - - - OMP_b-brl,OmpA,TSP_3 k141_3532_2 314282.PCNPT3_07050 6.7e-37 146.0 COG5492@1|root,COG5492@2|Bacteria,1PZBJ@1224|Proteobacteria,1RZEW@1236|Gammaproteobacteria 1236|Gammaproteobacteria N PFAM Ig domain protein, group 2 domain protein - - - - - - - - - - - - Big_2,DUF1566 k141_16644_1 42565.FP66_15025 1.46e-191 554.0 COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,1RMA7@1236|Gammaproteobacteria,1XHS6@135619|Oceanospirillales 135619|Oceanospirillales E aminopeptidase N pepN - 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - DUF3458,DUF3458_C,Peptidase_M1 k141_36657_1 1453501.JELR01000001_gene1925 2.76e-174 503.0 COG1506@1|root,COG1506@2|Bacteria,1MUJ3@1224|Proteobacteria,1RPAW@1236|Gammaproteobacteria,464D0@72275|Alteromonadaceae 1236|Gammaproteobacteria E X-Pro dipeptidyl-peptidase (S15 family) - - - - - - - - - - - - Peptidase_S9 k141_31772_1 986075.CathTA2_0966 2.15e-22 102.0 COG0577@1|root,COG0577@2|Bacteria,1URMS@1239|Firmicutes,4HCC6@91061|Bacilli 91061|Bacilli V efflux transmembrane transporter activity - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX k141_3533_1 1294265.JCM21738_2251 6.26e-64 201.0 COG1187@1|root,COG1187@2|Bacteria,1TQZ2@1239|Firmicutes,4H9VU@91061|Bacilli,1ZCAM@1386|Bacillus 91061|Bacilli J Belongs to the pseudouridine synthase RsuA family rsuA GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19 ko:K06183 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 k141_28396_1 935836.JAEL01000017_gene813 2.82e-59 197.0 COG3420@1|root,COG3420@2|Bacteria,1UN63@1239|Firmicutes,4HDJ8@91061|Bacilli,1ZRYJ@1386|Bacillus 91061|Bacilli P Periplasmic copper-binding protein (NosD) nosD - - ko:K07218 - - - - ko00000 - - - NosD k141_13157_1 316055.RPE_3491 9.24e-54 185.0 COG3420@1|root,COG3420@2|Bacteria,1NNDG@1224|Proteobacteria,2UNM9@28211|Alphaproteobacteria,3K2HK@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P Right handed beta helix region - - - - - - - - - - - - Beta_helix k141_7168_1 1453501.JELR01000002_gene829 6.59e-155 441.0 COG0524@1|root,COG0524@2|Bacteria,1MVG2@1224|Proteobacteria,1RNH5@1236|Gammaproteobacteria,465PF@72275|Alteromonadaceae 1236|Gammaproteobacteria G pfkB family carbohydrate kinase kdgK - 2.7.1.45 ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 M00061,M00308,M00631 R01541 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - PfkB k141_25003_1 644282.Deba_0052 3.96e-08 55.5 COG0010@1|root,COG0010@2|Bacteria,1MVFH@1224|Proteobacteria,42NBC@68525|delta/epsilon subdivisions,2WIMR@28221|Deltaproteobacteria 28221|Deltaproteobacteria E Belongs to the arginase family speB - 3.5.3.1,3.5.3.11 ko:K01476,ko:K01480 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 M00029,M00133,M00134 R00551,R01157 RC00024,RC00329 ko00000,ko00001,ko00002,ko01000 - - - Arginase k141_25003_2 1267533.KB906736_gene1109 2.83e-60 190.0 COG1945@1|root,COG1945@2|Bacteria,3Y3KR@57723|Acidobacteria,2JIBD@204432|Acidobacteriia 204432|Acidobacteriia S Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) - - 4.1.1.19 ko:K02626 ko00330,ko01100,map00330,map01100 M00133 R00566 RC00299 ko00000,ko00001,ko00002,ko01000 - - - PvlArgDC k141_15534_1 218284.CCDN010000006_gene3619 6.71e-50 173.0 COG1508@1|root,COG1508@2|Bacteria,1TQ0H@1239|Firmicutes,4HA8T@91061|Bacilli,1ZBKU@1386|Bacillus 91061|Bacilli K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog rpoN - - ko:K03092 ko02020,ko05111,map02020,map05111 - - - ko00000,ko00001,ko03021 - - - Sigma54_AID,Sigma54_CBD,Sigma54_DBD k141_34532_2 1279017.AQYJ01000020_gene1301 2.19e-76 237.0 COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,1S64Q@1236|Gammaproteobacteria,467V3@72275|Alteromonadaceae 1236|Gammaproteobacteria S Competence protein gntX GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0015976,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 - - - - - - - - - - Pribosyltran k141_21472_1 218284.CCDN010000001_gene88 3.72e-108 325.0 COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,4H9T1@91061|Bacilli,1ZB77@1386|Bacillus 91061|Bacilli M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan murE GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 ko:K01928 ko00300,ko00550,map00300,map00550 - R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M k141_22657_1 1453501.JELR01000002_gene136 1.44e-67 211.0 COG0321@1|root,COG0321@2|Bacteria,1MU6A@1224|Proteobacteria,1RMXQ@1236|Gammaproteobacteria,466J6@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate lipB GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0016874,GO:0016879,GO:0016979,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019222,GO:0019538,GO:0019752,GO:0032787,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048519,GO:0050789,GO:0051186,GO:0051188,GO:0051604,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0140096,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.3.1.181 ko:K03801 ko00785,ko01100,map00785,map01100 - R07766,R07769 RC00039,RC00992,RC02867 ko00000,ko00001,ko01000 - - iECSF_1327.ECSF_0569,iSFV_1184.SFV_0696,iSFxv_1172.SFxv_0718 BPL_LplA_LipB k141_17905_1 1279017.AQYJ01000019_gene1514 6.13e-204 582.0 COG5000@1|root,COG5000@2|Bacteria,1QVAT@1224|Proteobacteria,1T324@1236|Gammaproteobacteria,46D3E@72275|Alteromonadaceae 1236|Gammaproteobacteria T His Kinase A (phosphoacceptor) domain - - 2.7.13.3 ko:K02668 ko02020,map02020 M00501 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 - - - HATPase_c,HisKA k141_17905_2 1279017.AQYJ01000019_gene1513 6.96e-173 495.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,4642R@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains pilR - - ko:K02481,ko:K02667 ko02020,map02020 M00501 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - HTH_8,Response_reg,Sigma54_activat k141_11932_1 398511.BpOF4_16125 0.000193 45.1 COG4325@1|root,COG4325@2|Bacteria,1TSID@1239|Firmicutes,4HDM1@91061|Bacilli,1ZE04@1386|Bacillus 91061|Bacilli S Predicted membrane protein (DUF2254) - - - - - - - - - - - - DUF2254 k141_11932_2 218284.CCDN010000001_gene212 2.28e-31 110.0 COG4873@1|root,COG4873@2|Bacteria,1VF7M@1239|Firmicutes,4HPMH@91061|Bacilli,1ZIXH@1386|Bacillus 91061|Bacilli S protein conserved in bacteria ykvS - - - - - - - - - - - DUF2187 k141_11932_3 224308.BSU13819 2.36e-17 75.1 2EI19@1|root,33BSS@2|Bacteria,1VKXC@1239|Firmicutes,4HR2E@91061|Bacilli,1ZIUC@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_33337_2 491915.Aflv_1922 9.3e-58 181.0 COG0745@1|root,COG0745@2|Bacteria,1VAYR@1239|Firmicutes,4HKT2@91061|Bacilli,21X0D@150247|Anoxybacillus 91061|Bacilli KT cheY-homologous receiver domain - - - - - - - - - - - - Response_reg k141_29762_1 935863.AWZR01000003_gene2735 5.27e-25 102.0 COG0491@1|root,COG0491@2|Bacteria,1P5NJ@1224|Proteobacteria,1S04Y@1236|Gammaproteobacteria,1XBW9@135614|Xanthomonadales 135614|Xanthomonadales S Metallo-beta-lactamase superfamily - - 3.5.2.6 ko:K17837 ko01501,map01501 - R06363 RC01499 ko00000,ko00001,ko01000 - - - Lactamase_B k141_79_1 218284.CCDN010000001_gene1491 6.33e-65 199.0 COG1832@1|root,COG1832@2|Bacteria,1V7C7@1239|Firmicutes,4HIZT@91061|Bacilli,1ZG6W@1386|Bacillus 91061|Bacilli S CoA-binding protein yneT - - ko:K06929 - - - - ko00000 - - - CoA_binding_2 k141_6005_1 1116375.VEJY3_02535 0.0 1603.0 COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,1RN55@1236|Gammaproteobacteria,1XSEU@135623|Vibrionales 135623|Vibrionales O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE clpB GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564 - ko:K03695 ko04213,map04213 - - - ko00000,ko00001,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N k141_6005_2 1116375.VEJY3_02530 3.3e-152 430.0 COG1496@1|root,COG1496@2|Bacteria,1MW2H@1224|Proteobacteria,1RNV4@1236|Gammaproteobacteria,1XSY8@135623|Vibrionales 135623|Vibrionales S Belongs to the multicopper oxidase YfiH RL5 family yfiH - - ko:K05810 - - - - ko00000,ko01000 - - - Cu-oxidase_4 k141_6005_3 223926.28805542 2.41e-232 639.0 COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,1RN7F@1236|Gammaproteobacteria,1XSYP@135623|Vibrionales 135623|Vibrionales J Responsible for synthesis of pseudouridine from uracil rluD GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 ko:K06180 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 k141_6005_4 1116375.VEJY3_02520 1.14e-168 471.0 COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,1RSE6@1236|Gammaproteobacteria,1XSWB@135623|Vibrionales 135623|Vibrionales M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamD GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - ko:K05807 - - - - ko00000,ko02000 1.B.33.1 - - YfiO k141_6005_5 1116375.VEJY3_02515 5.65e-293 807.0 COG4623@1|root,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,1RM8W@1236|Gammaproteobacteria,1XUTK@135623|Vibrionales 135623|Vibrionales M Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella - - - - - - - - - - - - SBP_bac_3,SLT k141_6005_6 223926.28805539 3.05e-67 204.0 COG1544@1|root,COG1544@2|Bacteria,1RD2Y@1224|Proteobacteria,1S6GT@1236|Gammaproteobacteria,1XXCP@135623|Vibrionales 135623|Vibrionales J COG1544 Ribosome-associated protein Y (PSrp-1) raiA - - ko:K05809 - - - - ko00000,ko03009 - - - Ribosomal_S30AE k141_6005_7 674977.VMC_20980 1.59e-265 730.0 COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,1MU60@1224|Proteobacteria,1RNRD@1236|Gammaproteobacteria,1XT8C@135623|Vibrionales 135623|Vibrionales E chorismate mutase pheA - 4.2.1.51,5.4.99.5 ko:K14170 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024,M00025 R00691,R01373,R01715 RC00360,RC03116 ko00000,ko00001,ko00002,ko01000 - - - CM_2,PDT k141_6005_8 1116375.VEJY3_02500 1.55e-109 317.0 COG1986@1|root,COG1986@2|Bacteria,1RG2E@1224|Proteobacteria,1S5QG@1236|Gammaproteobacteria,1XUT8@135623|Vibrionales 135623|Vibrionales F Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions yjjX GO:0003674,GO:0003824,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111 - - - - - - - - - - NTPase_I-T k141_6005_9 223926.28805536 1.94e-51 164.0 COG2973@1|root,COG2973@2|Bacteria,1MYB2@1224|Proteobacteria,1S6RH@1236|Gammaproteobacteria,1XYA5@135623|Vibrionales 135623|Vibrionales K This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription trpR GO:0003674,GO:0003700,GO:0006082,GO:0006355,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009072,GO:0009308,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031326,GO:0034641,GO:0042430,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0140110,GO:1901360,GO:1901564,GO:1901605,GO:1903506,GO:2000112,GO:2001141 - ko:K03720 - - - - ko00000,ko03000 - - - Trp_repressor k141_6005_10 1116375.VEJY3_02490 0.0 1100.0 COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,1RMS8@1236|Gammaproteobacteria,1XUVC@135623|Vibrionales 135623|Vibrionales M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) slt - - ko:K08309 - - - - ko00000,ko01000,ko01011 - GH23 - SLT,SLT_L k141_6005_11 1116375.VEJY3_02485 0.0 1087.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPWS@1236|Gammaproteobacteria,1XSGT@135623|Vibrionales 135623|Vibrionales S COG0488 ATPase components of ABC transporters with duplicated ATPase domains yjjK - - - - - - - - - - - ABC_tran,ABC_tran_Xtn k141_6005_12 1116375.VEJY3_02480 3.24e-209 582.0 COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,1RMIR@1236|Gammaproteobacteria,1XTK9@135623|Vibrionales 135623|Vibrionales M COG0739 Membrane proteins related to metalloendopeptidases - - - - - - - - - - - - Peptidase_M23 k141_6005_13 1280001.BAOA01000005_gene3760 1.69e-57 188.0 COG0287@1|root,COG1605@1|root,COG0287@2|Bacteria,COG1605@2|Bacteria,1MVUT@1224|Proteobacteria,1RQB3@1236|Gammaproteobacteria,1XUE1@135623|Vibrionales 135623|Vibrionales E T-protein tyrA - 1.3.1.12,5.4.99.5 ko:K14187 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00024,M00025 R01715,R01728 RC00125,RC03116 ko00000,ko00001,ko00002,ko01000 - - - CM_2,PDH k141_28600_1 1247024.JRLH01000016_gene1680 1.33e-08 53.5 2EMPC@1|root,33FBT@2|Bacteria,1QNQV@1224|Proteobacteria,1SI44@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_3635_1 1279017.AQYJ01000027_gene1591 0.0 2064.0 COG0643@1|root,COG0784@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,4650G@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0643 Chemotaxis protein histidine kinase and related kinases chpA - - ko:K02487,ko:K06596 ko02020,ko02025,map02020,map02025 M00507 - - ko00000,ko00001,ko00002,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg k141_3635_2 1453501.JELR01000002_gene953 0.0 897.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,465M4@72275|Alteromonadaceae 1236|Gammaproteobacteria NT COG0840 Methyl-accepting chemotaxis protein pilJ - - ko:K02660 ko02020,ko02025,map02020,map02025 - - - ko00000,ko00001,ko02035,ko02044 - - - MCPsignal,PilJ k141_3635_6 1279017.AQYJ01000027_gene1595 2.2e-89 262.0 COG0745@1|root,COG0745@2|Bacteria,1RDYB@1224|Proteobacteria,1S4CZ@1236|Gammaproteobacteria,466ZB@72275|Alteromonadaceae 1236|Gammaproteobacteria KT COG0784 FOG CheY-like receiver pilG - - ko:K02657,ko:K03413 ko02020,ko02025,ko02030,map02020,map02025,map02030 M00506,M00507 - - ko00000,ko00001,ko00002,ko02022,ko02035,ko02044 - - - Response_reg k141_3635_7 1279017.AQYJ01000027_gene1596 1.37e-192 538.0 COG0189@1|root,COG0189@2|Bacteria,1MVUA@1224|Proteobacteria,1RMU0@1236|Gammaproteobacteria,4651A@72275|Alteromonadaceae 1236|Gammaproteobacteria H Belongs to the prokaryotic GSH synthase family gshB GO:0000287,GO:0003674,GO:0003824,GO:0004363,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0019184,GO:0034641,GO:0042398,GO:0043043,GO:0043167,GO:0043169,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:1901564,GO:1901566,GO:1901576 6.3.2.3 ko:K01920 ko00270,ko00480,ko01100,map00270,map00480,map01100 M00118 R00497,R10994 RC00096,RC00141 ko00000,ko00001,ko00002,ko01000 - - iECED1_1282.ECED1_3410,iECP_1309.ECP_2941 GSH-S_ATP,GSH-S_N k141_3635_8 1279017.AQYJ01000027_gene1597 3.02e-164 465.0 COG0810@1|root,COG0810@2|Bacteria,1MUMT@1224|Proteobacteria,1S3A6@1236|Gammaproteobacteria,465SW@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0810 Periplasmic protein TonB, links inner and outer membranes tonB3 - - ko:K03832 - - - - ko00000,ko02000 2.C.1.1 - - TonB_C k141_3635_9 1279017.AQYJ01000027_gene1598 2.57e-114 330.0 COG1678@1|root,COG1678@2|Bacteria,1RCXM@1224|Proteobacteria,1S3YV@1236|Gammaproteobacteria,466MP@72275|Alteromonadaceae 1236|Gammaproteobacteria K Belongs to the UPF0301 (AlgH) family yqgE GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K07735 - - - - ko00000,ko03000 - - - DUF179 k141_3635_10 1279017.AQYJ01000027_gene1599 1.22e-34 121.0 COG0816@1|root,COG0816@2|Bacteria,1RDHZ@1224|Proteobacteria,1S96Q@1236|Gammaproteobacteria,466VN@72275|Alteromonadaceae 1236|Gammaproteobacteria L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA yqgF GO:0000966,GO:0000967,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - ko:K07447 - - - - ko00000,ko01000 - - - RuvX k141_17906_2 218284.CCDN010000001_gene1888 2.93e-145 429.0 COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,4HA8S@91061|Bacilli,1ZBWA@1386|Bacillus 91061|Bacilli J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,IF-2,IF2_N k141_21473_1 218284.CCDN010000001_gene132 7e-118 367.0 COG1038@1|root,COG1038@2|Bacteria,1UHP9@1239|Firmicutes,4IS56@91061|Bacilli,1ZC4R@1386|Bacillus 91061|Bacilli C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second pyc - 6.4.1.1 ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 M00173 R00344 RC00040,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,HMGL-like,PYC_OADA k141_2451_1 218284.CCDN010000001_gene1831 9.21e-121 352.0 COG2046@1|root,COG2046@2|Bacteria,1TR4C@1239|Firmicutes,4HC20@91061|Bacilli,1ZCB4@1386|Bacillus 91061|Bacilli P Belongs to the sulfate adenylyltransferase family sat - 2.7.7.4 ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176,M00596 R00529,R04929 RC02809,RC02889 ko00000,ko00001,ko00002,ko01000 - - - ATP-sulfurylase,PUA_2 k141_9569_1 1240350.AMZE01000030_gene2034 1.33e-61 195.0 COG2032@1|root,COG2032@2|Bacteria,1RGV4@1224|Proteobacteria,1S6KW@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Destroys radicals which are normally produced within the cells and which are toxic to biological systems sodC GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0005488,GO:0005507,GO:0005575,GO:0005576,GO:0005615,GO:0005623,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008270,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0030288,GO:0030313,GO:0031975,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0042597,GO:0043167,GO:0043169,GO:0044237,GO:0044421,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1 ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 - - - ko00000,ko00001,ko01000 - - iEcolC_1368.EcolC_1983 Sod_Cu k141_16696_1 1385511.N783_11700 9.45e-99 299.0 COG0659@1|root,COG0659@2|Bacteria,1TT9Y@1239|Firmicutes,4HDPJ@91061|Bacilli,2YBGY@289201|Pontibacillus 91061|Bacilli P Psort location CytoplasmicMembrane, score - - - - - - - - - - - - Xan_ur_permease k141_16696_2 345219.Bcoa_1002 2.71e-40 146.0 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli,1ZAXK@1386|Bacillus 91061|Bacilli C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively gabD - 1.2.1.16,1.2.1.20,1.2.1.79 ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 M00027 R00713,R00714,R02401 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_25017_1 218284.CCDN010000005_gene3415 3.84e-114 335.0 COG2334@1|root,COG2334@2|Bacteria,1VEZ6@1239|Firmicutes,4HBAB@91061|Bacilli,1ZBAM@1386|Bacillus 91061|Bacilli S Spore coat protein yutH GO:0005575,GO:0005623,GO:0042601,GO:0042763,GO:0044464 - - - - - - - - - - - k141_10754_2 218284.CCDN010000001_gene1208 2.48e-75 236.0 COG1162@1|root,COG1162@2|Bacteria,1TP8Q@1239|Firmicutes,4H9PJ@91061|Bacilli,1ZCAI@1386|Bacillus 91061|Bacilli S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit rsgA_2 - 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 - R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 - - - RsgA_GTPase k141_13177_1 595593.JREV01000046_gene590 1.68e-27 112.0 COG0493@1|root,COG0493@2|Bacteria,2I57P@201174|Actinobacteria,1WAES@1268|Micrococcaceae 201174|Actinobacteria E NAD(P)-binding Rossmann-like domain - - - - - - - - - - - - NAD_binding_8 k141_27390_1 1279017.AQYJ01000020_gene1316 4.92e-121 366.0 COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,1RM95@1236|Gammaproteobacteria,465G3@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG4770 Acetyl propionyl-CoA carboxylase, alpha subunit mccA - 6.4.1.4 ko:K01968 ko00280,ko01100,map00280,map01100 M00036 R04138 RC00367,RC00942 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2 k141_98_1 997296.PB1_15919 3.04e-28 113.0 COG1388@1|root,COG1388@2|Bacteria,1U052@1239|Firmicutes,4HF2C@91061|Bacilli,1ZB2H@1386|Bacillus 91061|Bacilli M stage VI sporulation protein D spoVID GO:0003674,GO:0005488,GO:0005515,GO:0019899,GO:0051117 - ko:K06417 - - - - ko00000 - - - LysM k141_98_2 218284.CCDN010000001_gene607 3.14e-16 77.0 COG2334@1|root,COG2334@2|Bacteria,1V54J@1239|Firmicutes,4HH2K@91061|Bacilli,1ZB97@1386|Bacillus 91061|Bacilli S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response ysxE - - - - - - - - - - - APH k141_2483_1 118005.AWNK01000003_gene2462 5.38e-17 84.7 COG1409@1|root,COG2931@1|root,COG3209@1|root,COG5184@1|root,COG1409@2|Bacteria,COG2931@2|Bacteria,COG3209@2|Bacteria,COG5184@2|Bacteria 2|Bacteria DZ guanyl-nucleotide exchange factor activity - - - ko:K20276 ko02024,map02024 - - - ko00000,ko00001 - - - DUF1735,Flg_new,Laminin_G_3,Mfa_like_1,RCC1,RCC1_2 k141_11951_1 1116375.VEJY3_23146 9.55e-198 554.0 COG0438@1|root,COG0438@2|Bacteria,1N0Z5@1224|Proteobacteria,1SBK4@1236|Gammaproteobacteria,1XSA7@135623|Vibrionales 135623|Vibrionales M Glycosyl transferase 4-like domain - - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_4 k141_9582_1 221109.22776946 7.79e-36 131.0 COG0596@1|root,COG0596@2|Bacteria,1UTNC@1239|Firmicutes,4HDZI@91061|Bacilli,23JVT@182709|Oceanobacillus 91061|Bacilli S alpha/beta hydrolase fold - - 3.4.11.5 ko:K01259 ko00330,map00330 - R00135 - ko00000,ko00001,ko01000,ko01002 - - - Abhydrolase_1 k141_9582_2 997296.PB1_05200 2.2e-49 160.0 COG0346@1|root,COG0346@2|Bacteria,1V422@1239|Firmicutes,4HH25@91061|Bacilli,1ZG9A@1386|Bacillus 91061|Bacilli H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor fosB GO:0003674,GO:0003824,GO:0004364,GO:0008150,GO:0016740,GO:0016765,GO:0042221,GO:0046677,GO:0050896 - ko:K11210,ko:K21252 - - - - ko00000,ko01000,ko01504 - - - Glyoxalase k141_6030_1 545693.BMQ_2021 6.09e-91 282.0 COG1233@1|root,COG1233@2|Bacteria,1TQX8@1239|Firmicutes,4HBEI@91061|Bacilli,1ZBFN@1386|Bacillus 91061|Bacilli Q Flavin containing amine oxidoreductase crtP - 1.14.99.44 ko:K10210 ko00906,map00906 - R07654,R09671,R09727,R09728 RC00254,RC02089,RC02626,RC02638 ko00000,ko00001,ko01000 - - - Amino_oxidase k141_36905_1 1196031.ALEG01000033_gene3009 3.64e-227 640.0 COG1680@1|root,COG1680@2|Bacteria,1U828@1239|Firmicutes,4HA0Q@91061|Bacilli,1ZBJ0@1386|Bacillus 91061|Bacilli V Belongs to the UPF0214 family estB - 3.4.16.4 ko:K21469 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - Beta-lactamase,Peptidase_M6 k141_27391_1 1408303.JNJJ01000067_gene2259 4.18e-59 194.0 COG0477@1|root,COG2814@2|Bacteria,1TRRB@1239|Firmicutes,4HAUF@91061|Bacilli,1ZDMB@1386|Bacillus 91061|Bacilli EGP Major facilitator superfamily yfmO - - ko:K08221 - - - - ko00000,ko02000 2.A.1.32 - - MFS_1 k141_19089_1 218284.CCDN010000001_gene40 9.55e-132 379.0 COG1162@1|root,COG1162@2|Bacteria,1TPSQ@1239|Firmicutes,4HA9W@91061|Bacilli,1ZB4W@1386|Bacillus 91061|Bacilli S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit rsgA - 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 - R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 - - - RsgA_GTPase,RsgA_N k141_29784_1 315730.BcerKBAB4_5466 4.35e-89 270.0 COG2040@1|root,COG2040@2|Bacteria,1UHQ5@1239|Firmicutes,4HAS6@91061|Bacilli,1ZC9Q@1386|Bacillus 91061|Bacilli H homocysteine mmuM - 2.1.1.10 ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 - R00650 RC00003,RC00035 ko00000,ko00001,ko01000 - - - S-methyl_trans k141_29784_2 315730.BcerKBAB4_5465 5.48e-64 209.0 COG0833@1|root,COG0833@2|Bacteria,1UHNR@1239|Firmicutes,4HUT7@91061|Bacilli,1ZB12@1386|Bacillus 91061|Bacilli E amino acid ybgF - - ko:K02205,ko:K03293,ko:K16235,ko:K16236 - - - - ko00000,ko02000 2.A.3.1,2.A.3.1.10 - - AA_permease k141_99_1 42565.FP66_03640 1.93e-84 249.0 2DNQU@1|root,32YME@2|Bacteria,1N79E@1224|Proteobacteria,1SFA1@1236|Gammaproteobacteria 1236|Gammaproteobacteria S SpoIIAA-like - - - - - - - - - - - - SpoIIAA-like k141_35743_1 1294265.JCM21738_4150 2.07e-20 84.0 COG1939@1|root,COG1939@2|Bacteria,1VA5V@1239|Firmicutes,4HIM3@91061|Bacilli,1ZH0Z@1386|Bacillus 91061|Bacilli J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc) mrnC GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 - ko:K11145 - - - - ko00000,ko01000,ko03009 - - - Ribonuclease_3 k141_35743_2 1294265.JCM21738_4151 8.03e-43 151.0 COG0566@1|root,COG0566@2|Bacteria,1TP9G@1239|Firmicutes,4HBBI@91061|Bacilli,1ZAXC@1386|Bacillus 91061|Bacilli J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family trmH GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 ko:K03218 - - - - ko00000,ko01000,ko03009 - - - SpoU_methylase,SpoU_sub_bind k141_9583_1 218284.CCDN010000007_gene3860 4.53e-103 331.0 COG1674@1|root,COG1674@2|Bacteria,1TRA4@1239|Firmicutes,4H9QM@91061|Bacilli,1ZDSN@1386|Bacillus 91061|Bacilli D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins essC - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FHA,FtsK_SpoIIIE,FtsK_SpoIIIE_N k141_14357_1 441769.ABFU01000042_gene3261 7.27e-49 155.0 2E1GI@1|root,32WUX@2|Bacteria,1VB9C@1239|Firmicutes,4HNTC@91061|Bacilli,1ZQN9@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2626) - - - - - - - - - - - - DUF2626 k141_8423_1 1348635.BBJY01000016_gene3965 2.32e-135 397.0 COG1129@1|root,COG1129@2|Bacteria,1MU22@1224|Proteobacteria,1RMCH@1236|Gammaproteobacteria,1XY8T@135623|Vibrionales 135623|Vibrionales G Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - 3.6.3.17 ko:K02056 - M00221 - - ko00000,ko00002,ko01000,ko02000 3.A.1.2 - - ABC_tran k141_8423_2 1348635.BBJY01000016_gene3966 1.17e-188 528.0 COG1879@1|root,COG1879@2|Bacteria,1NRXG@1224|Proteobacteria,1RPBV@1236|Gammaproteobacteria,1XUF5@135623|Vibrionales 135623|Vibrionales G ABC-type sugar transport system, periplasmic component - - - ko:K10439 ko02010,ko02030,map02010,map02030 M00212 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - Peripla_BP_4 k141_8423_3 1116375.VEJY3_24121 5.7e-201 560.0 COG1172@1|root,COG1172@2|Bacteria,1MVN9@1224|Proteobacteria,1RPYE@1236|Gammaproteobacteria,1XWC5@135623|Vibrionales 135623|Vibrionales U Branched-chain amino acid transport system / permease component - - - ko:K10440,ko:K10538 ko02010,map02010 M00212,M00213 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.2 - - BPD_transp_2 k141_8423_4 1116375.VEJY3_24126 0.0 954.0 COG1129@1|root,COG1129@2|Bacteria,1MU22@1224|Proteobacteria,1RSMB@1236|Gammaproteobacteria,1XVYA@135623|Vibrionales 135623|Vibrionales G Part of the ABC transporter complex AraFGH involved in arabinose import. Responsible for energy coupling to the transport system araG - 3.6.3.17 ko:K10441,ko:K10539 ko02010,map02010 M00212,M00213 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.2 - - ABC_tran k141_8423_5 1116375.VEJY3_24131 1.05e-225 623.0 COG1879@1|root,COG1879@2|Bacteria,1MVDG@1224|Proteobacteria,1RMBR@1236|Gammaproteobacteria,1XTNH@135623|Vibrionales 135623|Vibrionales G Periplasmic binding protein domain - - - ko:K10537 ko02010,map02010 M00213 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.2 - - Peripla_BP_1 k141_8423_6 1348635.BBJY01000016_gene3970 0.0 1060.0 COG1069@1|root,COG1069@2|Bacteria,1MY11@1224|Proteobacteria,1RP3F@1236|Gammaproteobacteria,1XW8E@135623|Vibrionales 135623|Vibrionales C FGGY family of carbohydrate kinases, N-terminal domain araB - 2.7.1.16 ko:K00853 ko00040,ko01100,map00040,map01100 - R01526,R02439 RC00002,RC00538 ko00000,ko00001,ko01000 - - - FGGY_C,FGGY_N k141_8423_7 1348635.BBJY01000016_gene3971 1.82e-166 466.0 COG0235@1|root,COG0235@2|Bacteria,1MU54@1224|Proteobacteria,1RMIP@1236|Gammaproteobacteria,1XUM8@135623|Vibrionales 135623|Vibrionales G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases - - 5.1.3.4 ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 M00550 R05850 RC01479 ko00000,ko00001,ko00002,ko01000 - - - Aldolase_II k141_8423_8 1348635.BBJY01000016_gene3972 1.36e-291 800.0 COG2160@1|root,COG2160@2|Bacteria,1MW0J@1224|Proteobacteria,1RQEF@1236|Gammaproteobacteria,1XSFJ@135623|Vibrionales 135623|Vibrionales G Catalyzes the conversion of L-arabinose to L-ribulose araA - 5.3.1.4 ko:K01804 ko00040,ko01100,map00040,map01100 - R01761 RC00516 ko00000,ko00001,ko01000 - - - Arabinose_Iso_C,Arabinose_Isome k141_7192_3 1042377.AFPJ01000032_gene2798 9.89e-67 207.0 COG0802@1|root,COG0802@2|Bacteria,1RGYU@1224|Proteobacteria,1S6IB@1236|Gammaproteobacteria,467AG@72275|Alteromonadaceae 1236|Gammaproteobacteria S ATPase or kinase yjeE GO:0000166,GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043531,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 - ko:K06925 - - - - ko00000,ko03016 - - - TsaE k141_27392_1 315750.BPUM_1249 6.61e-31 119.0 COG0182@1|root,COG0182@2|Bacteria,1TPDK@1239|Firmicutes,4H9WM@91061|Bacilli,1ZCD9@1386|Bacillus 91061|Bacilli E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) mtnA GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 ko:K08963 ko00270,ko01100,map00270,map01100 M00034 R04420 RC01151 ko00000,ko00001,ko00002,ko01000 - - - IF-2B k141_6031_2 1279017.AQYJ01000029_gene3395 4.34e-94 281.0 COG1075@1|root,COG1075@2|Bacteria,1N2W0@1224|Proteobacteria,1S2JW@1236|Gammaproteobacteria,46749@72275|Alteromonadaceae 1236|Gammaproteobacteria S acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - - - - - - - - - - Abhydrolase_6,DUF676,Hydrolase_4 k141_3660_1 493475.GARC_3472 2.18e-32 126.0 COG0577@1|root,COG0577@2|Bacteria,1QSVW@1224|Proteobacteria,1RPBM@1236|Gammaproteobacteria,465M6@72275|Alteromonadaceae 1236|Gammaproteobacteria V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD k141_3660_2 1279017.AQYJ01000022_gene2698 8.81e-148 418.0 COG1136@1|root,COG1136@2|Bacteria,1NHCD@1224|Proteobacteria,1RNIX@1236|Gammaproteobacteria,464FN@72275|Alteromonadaceae 1236|Gammaproteobacteria V ABC transporter ycfV - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_3660_3 1279017.AQYJ01000022_gene2699 3.65e-199 564.0 COG0845@1|root,COG0845@2|Bacteria,1NQDN@1224|Proteobacteria,1RRFE@1236|Gammaproteobacteria,4652W@72275|Alteromonadaceae 1236|Gammaproteobacteria M Barrel-sandwich domain of CusB or HlyD membrane-fusion ybjY - - ko:K02005 - - - - ko00000 - - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 k141_3660_4 1279017.AQYJ01000022_gene2701 8.24e-312 855.0 COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,1RMCN@1236|Gammaproteobacteria,4647I@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0659 Sulfate permease and related transporters (MFS superfamily) - - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - STAS,Sulfate_transp k141_3660_5 857087.Metme_1911 2.7e-26 106.0 COG0589@1|root,COG0589@2|Bacteria,1PAFP@1224|Proteobacteria,1RSCS@1236|Gammaproteobacteria,1XEKF@135618|Methylococcales 135618|Methylococcales T Universal stress protein family - - - - - - - - - - - - Usp k141_34562_1 709032.Sulku_2264 2.57e-06 52.0 2DBBT@1|root,2Z8AC@2|Bacteria 2|Bacteria S Putative MetA-pathway of phenol degradation - - - - - - - - - - - - Phenol_MetA_deg k141_23830_2 1116375.VEJY3_16521 1.21e-228 635.0 COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,1RN0E@1236|Gammaproteobacteria,1XUQG@135623|Vibrionales 135623|Vibrionales M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K13888 - M00709 - - ko00000,ko00002,ko02000 8.A.1 - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 k141_23830_3 1116375.VEJY3_16526 0.0 1168.0 COG0577@1|root,COG1136@1|root,COG0577@2|Bacteria,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,1RNUJ@1236|Gammaproteobacteria,1XSYR@135623|Vibrionales 135623|Vibrionales V Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides macB - - ko:K05685 ko02010,map02010 M00709 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.122.1,3.A.1.122.12 - - ABC_tran,FtsX,MacB_PCD k141_23830_4 1116375.VEJY3_16531 2.67e-294 808.0 COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,1RN0I@1236|Gammaproteobacteria,1Y2PP@135623|Vibrionales 135623|Vibrionales MU Outer membrane efflux protein - - - - - - - - - - - - OEP k141_21497_1 1042377.AFPJ01000019_gene2548 3.7e-92 289.0 COG4776@1|root,COG4776@2|Bacteria,1P563@1224|Proteobacteria,1RP5G@1236|Gammaproteobacteria,46DF9@72275|Alteromonadaceae 1236|Gammaproteobacteria K RNB rnb GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0008859,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360,GO:1901361,GO:1901575 3.1.13.1 ko:K01147 - - - - ko00000,ko01000,ko03016 - - - OB_RNB,RNB,S1 k141_20265_2 218284.CCDN010000005_gene3297 6.62e-130 372.0 COG2357@1|root,COG2357@2|Bacteria,1TQ2F@1239|Firmicutes,4HA3Q@91061|Bacilli,1ZBM8@1386|Bacillus 91061|Bacilli S GTP pyrophosphokinase yjbM GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5 ko:K07816 ko00230,map00230 - R00429 RC00002,RC00078 ko00000,ko00001,ko01000 - - - RelA_SpoT k141_20265_3 218284.CCDN010000005_gene3296 1.43e-55 176.0 2E3PJ@1|root,32YMN@2|Bacteria,1VGBJ@1239|Firmicutes,4HNU4@91061|Bacilli,1ZIVU@1386|Bacillus 91061|Bacilli S Belongs to the UPF0738 family yjbL - - - - - - - - - - - - k141_9633_3 223926.28805681 1.43e-275 752.0 COG2933@1|root,COG2933@2|Bacteria,1MWBM@1224|Proteobacteria,1RMSB@1236|Gammaproteobacteria,1XV45@135623|Vibrionales 135623|Vibrionales J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily rlmM - 2.1.1.186 ko:K06968 - - - - ko00000,ko01000,ko03009 - - - FtsJ k141_9633_4 223926.28805680 2.28e-87 257.0 COG2363@1|root,COG2363@2|Bacteria,1MZX3@1224|Proteobacteria,1SCNB@1236|Gammaproteobacteria,1XXBJ@135623|Vibrionales 135623|Vibrionales S small membrane protein ygdD - - - - - - - - - - - DUF423 k141_9633_5 1116375.VEJY3_03195 1.95e-129 369.0 COG3571@1|root,COG3571@2|Bacteria,1RD20@1224|Proteobacteria,1S3Y4@1236|Gammaproteobacteria,1XU58@135623|Vibrionales 135623|Vibrionales S hydrolase of the alpha beta-hydrolase fold - - - ko:K07020 - - - - ko00000 - - - Abhydrolase_1,Abhydrolase_6,DLH k141_9633_6 1116375.VEJY3_03190 2.65e-215 595.0 COG0583@1|root,COG0583@2|Bacteria,1MWY0@1224|Proteobacteria,1RP7Q@1236|Gammaproteobacteria,1XUQR@135623|Vibrionales 135623|Vibrionales K Transcriptional regulator gcvA - - ko:K03566 ko02026,map02026 - - - ko00000,ko00001,ko03000 - - - HTH_1,LysR_substrate k141_9633_7 1116375.VEJY3_03185 0.0 911.0 COG0301@1|root,COG0607@1|root,COG0301@2|Bacteria,COG0607@2|Bacteria,1MWD3@1224|Proteobacteria,1RNZT@1236|Gammaproteobacteria,1XT1D@135623|Vibrionales 135623|Vibrionales H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS thiI GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.4 ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07461 - ko00000,ko00001,ko01000,ko03016 - - - THUMP,ThiI k141_9633_8 223926.28805676 9.4e-193 538.0 COG1360@1|root,COG1360@2|Bacteria,1QUFR@1224|Proteobacteria,1T1XE@1236|Gammaproteobacteria,1XSEG@135623|Vibrionales 135623|Vibrionales N Flagellar motor protein motB - - ko:K02557 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - MotB_plug,OmpA k141_9633_9 1219076.N646_2842 7.8e-161 452.0 COG1291@1|root,COG1291@2|Bacteria,1MXK3@1224|Proteobacteria,1RNRP@1236|Gammaproteobacteria,1XSQE@135623|Vibrionales 135623|Vibrionales N COG1291 Flagellar motor component pomA GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0009288,GO:0009425,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044425,GO:0044459,GO:0044461,GO:0044463,GO:0044464,GO:0071944,GO:0120100,GO:0120101 - ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - MotA_ExbB k141_9633_10 1219076.N646_2841 1.87e-46 149.0 COG1722@1|root,COG1722@2|Bacteria,1N72V@1224|Proteobacteria,1SC7N@1236|Gammaproteobacteria,1XYBF@135623|Vibrionales 135623|Vibrionales L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseB GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494 3.1.11.6 ko:K03602 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_S k141_9633_11 1219076.N646_2840 2.21e-113 331.0 COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,1RMKY@1236|Gammaproteobacteria,1XTUM@135623|Vibrionales 135623|Vibrionales H Belongs to the FPP GGPP synthase family ispA - 2.5.1.1,2.5.1.10 ko:K00795 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364 R01658,R02003 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 - - - polyprenyl_synt k141_201_1 1116375.VEJY3_14440 6.98e-61 195.0 COG0608@1|root,COG0608@2|Bacteria,1N37P@1224|Proteobacteria,1RQTR@1236|Gammaproteobacteria,1XTYY@135623|Vibrionales 135623|Vibrionales L single-stranded DNA 5'-3' exodeoxyribonuclease activity - - - - - - - - - - - - - k141_201_2 1116375.VEJY3_14445 1.6e-130 372.0 COG1309@1|root,COG1309@2|Bacteria,1R52P@1224|Proteobacteria,1S4F0@1236|Gammaproteobacteria,1Y24T@135623|Vibrionales 135623|Vibrionales K Bacterial transcriptional repressor - - - - - - - - - - - - TetR,TetR_N k141_201_3 1116375.VEJY3_14455 7.08e-224 618.0 COG2269@1|root,COG2269@2|Bacteria,1MU97@1224|Proteobacteria,1RMR9@1236|Gammaproteobacteria,1XSYN@135623|Vibrionales 135623|Vibrionales J With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P epmA GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006430,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 - ko:K04568 - - - - ko00000,ko01000,ko03012 - - - tRNA-synt_2 k141_8490_2 1318628.MARLIPOL_09521 1.28e-112 341.0 COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,1RN5K@1236|Gammaproteobacteria,466GP@72275|Alteromonadaceae 1236|Gammaproteobacteria MU Outer membrane efflux protein - - - ko:K18300 - M00641 - - ko00000,ko00002,ko01504,ko02000 1.B.17 - - OEP k141_12018_1 1110502.TMO_2552 6.57e-50 181.0 COG0550@1|root,COG1754@1|root,COG0550@2|Bacteria,COG1754@2|Bacteria,1MUFZ@1224|Proteobacteria,2TRGN@28211|Alphaproteobacteria,2JQAY@204441|Rhodospirillales 204441|Rhodospirillales L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topA - 5.99.1.2 ko:K03168 - - - - ko00000,ko01000,ko03032,ko03400 - - - Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom k141_7271_1 1294265.JCM21738_2087 3.44e-145 410.0 COG2345@1|root,COG2345@2|Bacteria,1UYQM@1239|Firmicutes,4HAZZ@91061|Bacilli,1ZC2X@1386|Bacillus 91061|Bacilli K Helix-turn-helix domain - - - - - - - - - - - - ATC_hydrolase,HTH_20 k141_26336_1 1123237.Salmuc_05545 1.48e-96 297.0 COG3243@1|root,COG3243@2|Bacteria,1MU68@1224|Proteobacteria,2TR7S@28211|Alphaproteobacteria 28211|Alphaproteobacteria I poly-beta-hydroxybutyrate polymerase phbC - - ko:K03821 ko00650,map00650 - R04254 RC00004 ko00000,ko00001,ko01000 - - - PHBC_N,PhaC_N k141_23884_1 218284.CCDN010000007_gene3877 3.61e-117 339.0 2C8AD@1|root,32RKP@2|Bacteria,1V1BI@1239|Firmicutes,4HFCW@91061|Bacilli,1ZE3F@1386|Bacillus 91061|Bacilli S Gas vesicle synthesis protein GvpL/GvpF - - - - - - - - - - - - GvpL_GvpF k141_23884_2 218284.CCDN010000007_gene3878 1.17e-54 171.0 2DRDP@1|root,33BB6@2|Bacteria,1VD3J@1239|Firmicutes,4HNDU@91061|Bacilli,1ZI2X@1386|Bacillus 91061|Bacilli S Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth - - - - - - - - - - - - Gas_vesicle k141_9634_1 218284.CCDN010000002_gene2224 8.31e-90 270.0 COG1291@1|root,COG1291@2|Bacteria,1TRH1@1239|Firmicutes,4HAXG@91061|Bacilli,1ZB8I@1386|Bacillus 91061|Bacilli N flagellar motor motA GO:0001539,GO:0005575,GO:0005623,GO:0005886,GO:0006928,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0040011,GO:0044425,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071944,GO:0071973,GO:0071978,GO:0097588 - ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - MotA_ExbB k141_9634_2 218284.CCDN010000002_gene2223 1.2e-51 179.0 COG0840@1|root,COG0840@2|Bacteria,1V0SD@1239|Firmicutes,4HD8P@91061|Bacilli,1ZCT0@1386|Bacillus 91061|Bacilli NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - MCPsignal k141_33402_2 1116375.VEJY3_24011 3.19e-208 582.0 COG0515@1|root,COG0515@2|Bacteria,1R4X3@1224|Proteobacteria,1RSH9@1236|Gammaproteobacteria,1XTFZ@135623|Vibrionales 135623|Vibrionales KLT serine threonine protein kinase - - - - - - - - - - - - - k141_7273_2 324057.Pjdr2_6039 9.68e-42 144.0 COG3000@1|root,COG3000@2|Bacteria,1V2XN@1239|Firmicutes,4HFS5@91061|Bacilli,26X5T@186822|Paenibacillaceae 91061|Bacilli I Fatty acid hydroxylase superfamily - - - - - - - - - - - - FA_hydroxylase k141_8492_1 218284.CCDN010000001_gene270 6.07e-140 416.0 COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,4H9SP@91061|Bacilli,1ZAPS@1386|Bacillus 91061|Bacilli P COG2217 Cation transport ATPase cadA - 3.6.3.3,3.6.3.5 ko:K01534 - - - - ko00000,ko01000 3.A.3.6 - - E1-E2_ATPase,HMA,Hydrolase k141_203_1 1294265.JCM21738_96 1.42e-28 110.0 COG0539@1|root,COG0539@2|Bacteria,1TQ9N@1239|Firmicutes,4H9PX@91061|Bacilli,1ZARR@1386|Bacillus 91061|Bacilli J Ribosomal protein S1 rpsA - - ko:K02945 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - S1 k141_203_2 1294265.JCM21738_97 6.17e-87 261.0 COG1304@1|root,COG1304@2|Bacteria,1TQZ3@1239|Firmicutes,4HAMV@91061|Bacilli,1ZCXC@1386|Bacillus 91061|Bacilli C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) fni GO:0003674,GO:0003824,GO:0004452,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016853,GO:0016860,GO:0016863,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0071704,GO:1901576 5.3.3.2 ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095,M00096,M00364,M00365,M00366,M00367 R01123 RC00455 ko00000,ko00001,ko00002,ko01000 - - - FMN_dh k141_3739_1 1260251.SPISAL_06860 1.81e-68 225.0 COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,1RNGW@1236|Gammaproteobacteria,1WWDS@135613|Chromatiales 135613|Chromatiales M Catalyzes cross-linking of the peptidoglycan cell wall at the division septum ftsI - 3.4.16.4 ko:K03587 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011,ko03036 - - - PBP_dimer,Transpeptidase k141_34627_1 1453501.JELR01000006_gene12 7.75e-57 181.0 COG3023@1|root,COG3023@2|Bacteria,1RDHU@1224|Proteobacteria,1S3PG@1236|Gammaproteobacteria,46701@72275|Alteromonadaceae 1236|Gammaproteobacteria V COG3023 Negative regulator of beta-lactamase expression ampD GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043170,GO:0044424,GO:0044464,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 3.5.1.28 ko:K01447,ko:K03806 - - R04112 RC00064,RC00141 ko00000,ko01000,ko01011 - - iAF1260.b0110,iB21_1397.B21_00108,iBWG_1329.BWG_0103,iEC55989_1330.EC55989_0103,iECBD_1354.ECBD_3509,iECB_1328.ECB_00109,iECDH10B_1368.ECDH10B_0090,iECDH1ME8569_1439.ECDH1ME8569_0104,iECD_1391.ECD_00109,iECIAI1_1343.ECIAI1_0107,iECO103_1326.ECO103_0110,iECO111_1330.ECO111_0111,iECO26_1355.ECO26_0112,iECSE_1348.ECSE_0110,iECW_1372.ECW_m0107,iEKO11_1354.EKO11_3806,iETEC_1333.ETEC_0106,iEcDH1_1363.EcDH1_3492,iEcE24377_1341.EcE24377A_0112,iEcHS_1320.EcHS_A0114,iEcolC_1368.EcolC_3549,iJO1366.b0110,iSFV_1184.SFV_0101,iSF_1195.SF0107,iSFxv_1172.SFxv_0113,iS_1188.S0109,iUMNK88_1353.UMNK88_108,iWFL_1372.ECW_m0107,iY75_1357.Y75_RS00560 Amidase_2 k141_34627_2 1279017.AQYJ01000023_gene3249 3.26e-142 409.0 COG3725@1|root,COG3725@2|Bacteria,1RH1N@1224|Proteobacteria,1S6GK@1236|Gammaproteobacteria,467BI@72275|Alteromonadaceae 1236|Gammaproteobacteria V Membrane protein required for beta-lactamase induction ampE - - ko:K03807 - - - - ko00000 - - - AmpE k141_34627_3 1279017.AQYJ01000023_gene3250 3.22e-230 645.0 COG1012@1|root,COG1012@2|Bacteria,1MVGW@1224|Proteobacteria,1RN53@1236|Gammaproteobacteria,4656Y@72275|Alteromonadaceae 1236|Gammaproteobacteria C belongs to the aldehyde dehydrogenase family ywdH - 1.2.1.3 ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_31091_1 926692.AZYG01000047_gene2654 5.57e-85 266.0 COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,25E76@186801|Clostridia,3WB0C@53433|Halanaerobiales 186801|Clostridia F Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain purD - 6.3.4.13 ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144 RC00090,RC00166 ko00000,ko00001,ko00002,ko01000 - - - GARS_A,GARS_C,GARS_N k141_12020_1 313596.RB2501_12302 2.41e-58 202.0 COG2091@1|root,COG2091@2|Bacteria,4NGXG@976|Bacteroidetes,1HZ27@117743|Flavobacteriia 976|Bacteroidetes H lysine biosynthetic process via aminoadipic acid - - - - - - - - - - - - CBM9_1 k141_29844_1 1283284.AZUK01000001_gene30 3.86e-170 487.0 COG2723@1|root,COG2723@2|Bacteria,1MWG6@1224|Proteobacteria,1RMM2@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Belongs to the glycosyl hydrolase 1 family bglA GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008422,GO:0015926,GO:0016787,GO:0016798,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901135,GO:1901657 3.2.1.21,3.2.1.86 ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 - R00026,R00839,R02558,R02887,R02985,R03527,R04949,R04998,R05133,R05134,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - GT1 iEC55989_1330.EC55989_3188,iSSON_1240.SSON_3054 Glyco_hydro_1 k141_29844_2 1116375.VEJY3_02930 6.64e-98 295.0 COG4977@1|root,COG4977@2|Bacteria,1Q7DC@1224|Proteobacteria,1RQ1U@1236|Gammaproteobacteria,1XVE3@135623|Vibrionales 135623|Vibrionales K helix_turn_helix, arabinose operon control protein - - - ko:K02855 - - - - ko00000,ko03000 - - - AraC_binding,HTH_18 k141_204_1 1279017.AQYJ01000023_gene3085 3.55e-76 244.0 COG0471@1|root,COG0569@1|root,COG0471@2|Bacteria,COG0569@2|Bacteria,1MU0K@1224|Proteobacteria,1RMI1@1236|Gammaproteobacteria,464A6@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0471 Di- and tricarboxylate transporters - - - - - - - - - - - - CitMHS,TrkA_C k141_16804_6 1116375.VEJY3_13285 8.46e-214 592.0 COG3026@1|root,COG3026@2|Bacteria,1MUQ8@1224|Proteobacteria,1RNF3@1236|Gammaproteobacteria,1XSY1@135623|Vibrionales 135623|Vibrionales T COG3026 Negative regulator of sigma E activity rseB - - ko:K03598 - - - - ko00000,ko03021 - - - MucB_RseB,MucB_RseB_C k141_16804_7 223926.28807587 7.32e-132 376.0 COG3073@1|root,COG3073@2|Bacteria,1R4U0@1224|Proteobacteria,1RN98@1236|Gammaproteobacteria,1XSUI@135623|Vibrionales 135623|Vibrionales T An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E rseA - - ko:K03597 - - - - ko00000,ko03021 - - - RseA_C,RseA_N k141_16804_8 1280001.BAOA01000068_gene2679 7.6e-131 372.0 COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,1RN64@1236|Gammaproteobacteria,1XT4Z@135623|Vibrionales 135623|Vibrionales K Belongs to the sigma-70 factor family. ECF subfamily rpoE - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_16804_9 1116375.VEJY3_13300 0.0 1068.0 COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,1RMMD@1236|Gammaproteobacteria,1XT0I@135623|Vibrionales 135623|Vibrionales H Catalyzes the oxidation of L-aspartate to iminoaspartate nadB GO:0001716,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008734,GO:0009117,GO:0009987,GO:0015922,GO:0016491,GO:0016638,GO:0016641,GO:0019362,GO:0019637,GO:0019674,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:1901360,GO:1901564 1.4.3.16 ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 M00115 R00357,R00481 RC00006,RC02566 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C k141_9658_2 1279017.AQYJ01000028_gene2056 2.86e-294 829.0 COG1629@1|root,COG4771@2|Bacteria,1MW7D@1224|Proteobacteria,1RNET@1236|Gammaproteobacteria,46DCQ@72275|Alteromonadaceae 1236|Gammaproteobacteria P TonB dependent receptor oprC - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_14451_2 223926.28807731 0.0 1137.0 COG0155@1|root,COG0155@2|Bacteria,1MVVB@1224|Proteobacteria,1RMFH@1236|Gammaproteobacteria,1XTQM@135623|Vibrionales 135623|Vibrionales H Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate cysI GO:0003674,GO:0003824,GO:0004783,GO:0005575,GO:0005622,GO:0005623,GO:0006790,GO:0008150,GO:0008152,GO:0009337,GO:0009987,GO:0016002,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016673,GO:0019419,GO:0032991,GO:0044237,GO:0044424,GO:0044464,GO:0050311,GO:0055114 1.8.1.2 ko:K00381 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00176 R00858 RC00065 ko00000,ko00001,ko00002,ko01000 - - - NIR_SIR,NIR_SIR_ferr k141_14451_3 1116375.VEJY3_13935 2.37e-174 487.0 COG0175@1|root,COG0175@2|Bacteria,1MXUR@1224|Proteobacteria,1RNC5@1236|Gammaproteobacteria,1XTU8@135623|Vibrionales 135623|Vibrionales EH Belongs to the PAPS reductase family. CysH subfamily cysH GO:0003674,GO:0003824,GO:0004604,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016667,GO:0016671,GO:0044237,GO:0044424,GO:0044464,GO:0055114 1.8.4.10,1.8.4.8 ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00176 R02021 RC00007,RC02862 ko00000,ko00001,ko00002,ko01000 - - - PAPS_reduct k141_12045_2 1116375.VEJY3_10930 4.57e-244 671.0 COG4658@1|root,COG4658@2|Bacteria,1MVY6@1224|Proteobacteria,1RMEU@1236|Gammaproteobacteria,1XSQB@135623|Vibrionales 135623|Vibrionales C Part of a membrane complex involved in electron transport rnfD GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0044464,GO:0055114,GO:0071944 - ko:K03614 - - - - ko00000 - - - NQR2_RnfD_RnfE k141_12045_3 223926.28807099 3.14e-137 389.0 COG4659@1|root,COG4659@2|Bacteria,1RDEP@1224|Proteobacteria,1RPAD@1236|Gammaproteobacteria,1XU3Z@135623|Vibrionales 135623|Vibrionales C Part of a membrane complex involved in electron transport rnfG GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0055114 - ko:K03612 - - - - ko00000 - - - FMN_bind k141_12045_4 1116375.VEJY3_10940 2.55e-150 424.0 COG4660@1|root,COG4660@2|Bacteria,1MW6N@1224|Proteobacteria,1RMEH@1236|Gammaproteobacteria,1XT8E@135623|Vibrionales 135623|Vibrionales C Part of a membrane complex involved in electron transport rnfE GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0044464,GO:0055114,GO:0071944 - ko:K03613 - - - - ko00000 - - - Rnf-Nqr k141_12045_5 223926.28807101 1.03e-152 429.0 COG0177@1|root,COG0177@2|Bacteria,1MUYQ@1224|Proteobacteria,1RMHU@1236|Gammaproteobacteria,1XTIS@135623|Vibrionales 135623|Vibrionales L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate nth - 4.2.99.18 ko:K10773 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD k141_12045_6 1219076.N646_1184 8.78e-97 281.0 COG0346@1|root,COG0346@2|Bacteria,1RCYX@1224|Proteobacteria,1S1Z9@1236|Gammaproteobacteria,1XX01@135623|Vibrionales 135623|Vibrionales E Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione gloA GO:0003674,GO:0003824,GO:0004462,GO:0006518,GO:0006575,GO:0006749,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016846,GO:0034641,GO:0043603,GO:0044237,GO:0051186,GO:0071704,GO:1901564 4.4.1.5 ko:K01759 ko00620,map00620 - R02530 RC00004,RC00740 ko00000,ko00001,ko01000 - - - Glyoxalase k141_12045_7 1280001.BAOA01000020_gene359 3.52e-99 288.0 2CI7H@1|root,340FI@2|Bacteria,1NZE9@1224|Proteobacteria,1SQ3J@1236|Gammaproteobacteria,1XWRV@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF2753) VV13101 - - - - - - - - - - - DUF2753 k141_12045_8 1191299.AJYX01000056_gene2761 1.69e-43 149.0 COG2885@1|root,COG2885@2|Bacteria,1PGGZ@1224|Proteobacteria,1RNFU@1236|Gammaproteobacteria,1XUNB@135623|Vibrionales 135623|Vibrionales N flagellar protein MotY motY - - ko:K21218 ko02040,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - OmpA k141_26360_1 1453501.JELR01000002_gene1533 1.22e-83 266.0 COG0038@1|root,COG0038@2|Bacteria,1MV4K@1224|Proteobacteria,1RQJW@1236|Gammaproteobacteria,465J9@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0038 Chloride channel protein EriC eriC - - ko:K03281 - - - - ko00000 2.A.49 - - Voltage_CLC k141_33415_1 441769.ABFU01000013_gene2458 5.51e-88 273.0 COG0591@1|root,COG0591@2|Bacteria,1TPVE@1239|Firmicutes,4H9KW@91061|Bacilli,1ZB64@1386|Bacillus 91061|Bacilli E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - ko:K11928 - - - - ko00000,ko02000 2.A.21.2 - - SSF k141_22752_1 933115.GPDM_13201 1.17e-71 230.0 COG1233@1|root,COG1233@2|Bacteria,1TS4A@1239|Firmicutes,4HB9J@91061|Bacilli,26D9H@186818|Planococcaceae 91061|Bacilli Q Flavin containing amine oxidoreductase - - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 ko:K10027 ko00906,ko01100,ko01110,map00906,map01100,map01110 - R04787,R04798,R04800,R09691,R09692 RC01214,RC02088,RC02605 ko00000,ko00001,ko01000 - - - Amino_oxidase k141_22752_2 1273538.G159_08495 3.21e-131 388.0 COG1233@1|root,COG1233@2|Bacteria,1TRN1@1239|Firmicutes,4HA5W@91061|Bacilli,26GK0@186818|Planococcaceae 91061|Bacilli Q phytoene - - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 ko:K10027 ko00906,ko01100,ko01110,map00906,map01100,map01110 - R04787,R04798,R04800,R09691,R09692 RC01214,RC02088,RC02605 ko00000,ko00001,ko01000 - - - Amino_oxidase k141_21609_1 218284.CCDN010000002_gene2007 2.07e-73 233.0 COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,4H9VZ@91061|Bacilli,1ZC2Y@1386|Bacillus 91061|Bacilli E acetylornithine aminotransferase argD GO:0003674,GO:0003824,GO:0003992,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.11,2.6.1.17 ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R02283,R04475 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 k141_21609_2 218284.CCDN010000002_gene2008 3.86e-56 185.0 COG0505@1|root,COG0505@2|Bacteria,1TQ8N@1239|Firmicutes,4HAYC@91061|Bacilli,1ZBBD@1386|Bacillus 91061|Bacilli F Carbamoyl-phosphate synthetase glutamine chain carA GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_sm_chain,GATase k141_23909_1 218284.CCDN010000005_gene3451 4.31e-89 279.0 COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4HBBB@91061|Bacilli,1ZCKA@1386|Bacillus 91061|Bacilli M Penicillin-binding Protein pbpD - 2.4.1.129,3.4.16.4 ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase k141_35785_1 1177154.Y5S_01706 1.06e-192 587.0 COG1361@1|root,COG1361@2|Bacteria,1QVSF@1224|Proteobacteria 1224|Proteobacteria M domain protein - - - - - - - - - - - - CARDB,DUF11,OmpA_membrane k141_35785_2 1279017.AQYJ01000026_gene59 1.1e-197 563.0 COG0810@1|root,COG0810@2|Bacteria,1R65W@1224|Proteobacteria,1S133@1236|Gammaproteobacteria,466F5@72275|Alteromonadaceae 1236|Gammaproteobacteria M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - - - - - - - - - - TonB_C k141_35785_3 1279017.AQYJ01000026_gene60 1.44e-74 229.0 COG0848@1|root,COG0848@2|Bacteria,1RENY@1224|Proteobacteria,1S3TB@1236|Gammaproteobacteria 1236|Gammaproteobacteria U biopolymer transport protein - - - - - - - - - - - - ExbD k141_35785_4 1279017.AQYJ01000026_gene61 1.42e-91 273.0 COG0848@1|root,COG0848@2|Bacteria,1RHI8@1224|Proteobacteria,1S6FK@1236|Gammaproteobacteria,46BMC@72275|Alteromonadaceae 1236|Gammaproteobacteria U Biopolymer transport protein ExbD/TolR - - - - - - - - - - - - ExbD k141_35785_6 1279017.AQYJ01000026_gene63 7.43e-37 127.0 2EQ5T@1|root,33HS3@2|Bacteria,1NMTN@1224|Proteobacteria,1SIGB@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_35785_7 1279017.AQYJ01000026_gene64 4.87e-76 233.0 COG0457@1|root,COG0457@2|Bacteria,1NB8N@1224|Proteobacteria,1SEZN@1236|Gammaproteobacteria,4697B@72275|Alteromonadaceae 1236|Gammaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_1,TPR_11,TPR_12,TPR_16,TPR_17,TPR_19,TPR_2,TPR_6,TPR_8 k141_35785_8 1279017.AQYJ01000026_gene65 0.0 1075.0 COG4105@1|root,COG4105@2|Bacteria,1QVQ9@1224|Proteobacteria,1RSIG@1236|Gammaproteobacteria,46DC5@72275|Alteromonadaceae 1236|Gammaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16,TPR_6 k141_32203_1 649639.Bcell_3942 1.75e-42 142.0 29RPM@1|root,30CT2@2|Bacteria,1UABF@1239|Firmicutes,4IKPJ@91061|Bacilli,1ZHBC@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_36977_1 523791.Kkor_0376 2.15e-110 333.0 COG0654@1|root,COG0654@2|Bacteria,1R7UC@1224|Proteobacteria,1S1B9@1236|Gammaproteobacteria,1XQV5@135619|Oceanospirillales 135619|Oceanospirillales CH FAD binding domain - - 1.14.13.9 ko:K00486 ko00380,ko01100,map00380,map01100 M00038 R01960 RC00046 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_3 k141_12046_2 1453501.JELR01000005_gene1592 1.04e-79 243.0 COG3468@1|root,COG3468@2|Bacteria,1NTR4@1224|Proteobacteria,1T238@1236|Gammaproteobacteria,465K5@72275|Alteromonadaceae 1236|Gammaproteobacteria MU Protein of unknown function (DUF3014) - - - - - - - - - - - - DUF3014 k141_4912_2 1116375.VEJY3_18111 1.02e-76 229.0 COG3384@1|root,COG3384@2|Bacteria,1RIBC@1224|Proteobacteria,1SYBG@1236|Gammaproteobacteria,1Y2ST@135623|Vibrionales 135623|Vibrionales S Aromatic-ring-opening dioxygenase LigAB, LigA subunit - - 1.13.11.8 ko:K04100 ko00362,ko00624,ko00627,ko01120,map00362,map00624,map00627,map01120 - R01632,R03550,R04280,R09565 RC00233,RC00387,RC00535,RC02567,RC02694 br01602,ko00000,ko00001,ko01000 - - - LigA k141_2572_1 218284.CCDN010000006_gene3655 1.35e-123 378.0 COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,4HAW9@91061|Bacilli,1ZARC@1386|Bacillus 91061|Bacilli L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate uvrA - - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran k141_34653_2 218284.CCDN010000001_gene1404 5.4e-56 177.0 COG2210@1|root,COG2210@2|Bacteria,1V2R5@1239|Firmicutes,4HG2Y@91061|Bacilli,1ZC42@1386|Bacillus 91061|Bacilli O DsrE/DsrF/DrsH-like family yrkE - - - - - - - - - - - DrsE_2,Rhodanese,TusA k141_33416_1 1279009.ADICEAN_00534 9.64e-53 183.0 COG1404@1|root,COG1404@2|Bacteria 2|Bacteria O Belongs to the peptidase S8 family isp - - ko:K13275 - - - - ko00000,ko01000,ko01002,ko03110 - - - Peptidase_S8 k141_237_1 1042377.AFPJ01000042_gene1092 1.75e-59 207.0 COG0770@1|root,COG2843@1|root,COG0770@2|Bacteria,COG2843@2|Bacteria,1QTSF@1224|Proteobacteria,1RMGD@1236|Gammaproteobacteria,464UU@72275|Alteromonadaceae 1236|Gammaproteobacteria M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein - - - - - - - - - - - - Mur_ligase_C,Mur_ligase_M,PGA_cap k141_27473_2 314292.VAS14_10104 5.03e-91 270.0 COG1670@1|root,COG1670@2|Bacteria,1RKXE@1224|Proteobacteria,1SYJJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Gcn5-related n-acetyltransferase - - - ko:K03817 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 k141_35786_1 218284.CCDN010000005_gene3474 1.05e-121 360.0 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4HB97@91061|Bacilli,1ZBGZ@1386|Bacillus 91061|Bacilli C Belongs to the aldehyde dehydrogenase family ywdH - 1.2.1.3 ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_36978_1 1294265.JCM21738_1651 5.14e-112 325.0 COG0107@1|root,COG0107@2|Bacteria,1TP0W@1239|Firmicutes,4HAAM@91061|Bacilli,1ZAUX@1386|Bacillus 91061|Bacilli E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit hisF GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS14115 His_biosynth k141_32204_1 218284.CCDN010000001_gene1247 2.55e-122 357.0 COG1215@1|root,COG1215@2|Bacteria,1UE3Q@1239|Firmicutes,4HCUV@91061|Bacilli,1ZBHH@1386|Bacillus 91061|Bacilli M Glycosyl transferase family 21 - - - - - - - - - - - - Glyco_tranf_2_3,Glycos_transf_2 k141_15657_1 666686.B1NLA3E_00895 1.86e-95 291.0 COG1232@1|root,COG1232@2|Bacteria,1TQ6W@1239|Firmicutes,4HAUG@91061|Bacilli,1ZANK@1386|Bacillus 91061|Bacilli H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX hemY - 1.3.3.15,1.3.3.4 ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03222,R04178 RC00885 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS09325 Amino_oxidase k141_25093_2 218284.CCDN010000004_gene3150 1.15e-35 132.0 COG0189@1|root,COG0189@2|Bacteria,1UZ79@1239|Firmicutes,4HTI1@91061|Bacilli,1ZBQZ@1386|Bacillus 91061|Bacilli HJ COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase) - - - - - - - - - - - - ATPgrasp_YheCD k141_33417_1 1453501.JELR01000002_gene476 2.1e-47 172.0 COG3525@1|root,COG3525@2|Bacteria,1MVDE@1224|Proteobacteria,1RMNI@1236|Gammaproteobacteria,465UJ@72275|Alteromonadaceae 1236|Gammaproteobacteria G Glycosyl hydrolase family 20, domain 2 nahA - 3.2.1.52 ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 M00079 R00022,R06004,R11316 RC00049 ko00000,ko00001,ko00002,ko01000,ko03110 - GH20 - CHB_HEX_C_1,Glyco_hydro_20,Glyco_hydro_20b k141_1307_1 218284.CCDN010000001_gene685 7.83e-142 422.0 COG0507@1|root,COG0507@2|Bacteria,1TPZH@1239|Firmicutes,4HATQ@91061|Bacilli,1ZAYS@1386|Bacillus 91061|Bacilli L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity recD2 - 3.1.11.5 ko:K03581 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_30,HHH_4,HHH_5,UvrD_C_2 k141_20328_1 1294265.JCM21738_3222 5.13e-70 218.0 COG1475@1|root,COG1475@2|Bacteria,1TP0I@1239|Firmicutes,4HAC6@91061|Bacilli,1ZCDV@1386|Bacillus 91061|Bacilli D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage noc - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc k141_2573_2 1280944.HY17_01350 5.29e-35 128.0 COG3047@1|root,COG3047@2|Bacteria,1NUZJ@1224|Proteobacteria,2TRGI@28211|Alphaproteobacteria,43XDD@69657|Hyphomonadaceae 28211|Alphaproteobacteria M COG3047 Outer membrane protein W ompW - - ko:K07275 - - - - ko00000 - - - OmpW k141_23911_2 1279017.AQYJ01000022_gene2740 4.18e-62 199.0 COG3219@1|root,COG3219@2|Bacteria,1R8C9@1224|Proteobacteria,1S23S@1236|Gammaproteobacteria,4673F@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria - - - ko:K09929 - - - - ko00000 - - - DUF2063 k141_7303_1 218284.CCDN010000007_gene3993 2.56e-32 113.0 COG5336@1|root,COG5336@2|Bacteria,1VF5M@1239|Firmicutes,4HNYV@91061|Bacilli,1ZJ1K@1386|Bacillus 91061|Bacilli S Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - - - - - - - - - - ATPase_gene1 k141_7303_2 796606.BMMGA3_16015 1.27e-46 153.0 2E2UM@1|root,32XWN@2|Bacteria,1VDFF@1239|Firmicutes,4HJ3R@91061|Bacilli,1ZH6N@1386|Bacillus 91061|Bacilli S ATP synthase I chain atpI - - ko:K02116 - - - - ko00000,ko00194 3.A.2.1 - - ATP-synt_I k141_9681_1 1231057.AMGD01000002_gene2315 2.81e-05 52.0 COG2199@1|root,COG2202@1|root,COG2199@2|Bacteria,COG2202@2|Bacteria,1UQA9@1239|Firmicutes,4HBNE@91061|Bacilli,26DYS@186818|Planococcaceae 91061|Bacilli T Diguanylate cyclase - - - - - - - - - - - - GGDEF,PAS_4,PAS_9 k141_7357_1 1116375.VEJY3_16596 1.74e-236 658.0 COG0665@1|root,COG0665@2|Bacteria,1MVGP@1224|Proteobacteria,1RNJ9@1236|Gammaproteobacteria,1XSCR@135623|Vibrionales 135623|Vibrionales E COG0665 Glycine D-amino acid oxidases (deaminating) - - - - - - - - - - - - DAO k141_26424_1 1042877.GQS_02785 1.38e-18 89.7 COG2233@1|root,arCOG02805@2157|Archaea,2XSTR@28890|Euryarchaeota,245FY@183968|Thermococci 183968|Thermococci F Permease family - - - ko:K02824,ko:K03458 - - - - ko00000,ko02000 2.A.40,2.A.40.1.1,2.A.40.1.2 - - Xan_ur_permease k141_29886_1 272558.10174774 9.64e-87 263.0 COG1011@1|root,COG1011@2|Bacteria,1TS3W@1239|Firmicutes,4HADE@91061|Bacilli,1ZBN8@1386|Bacillus 91061|Bacilli S HAD-hyrolase-like ysaA - 3.1.3.5,3.8.1.2 ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346,R05287 RC00017,RC00697 ko00000,ko00001,ko01000 - - - HAD_2 k141_28792_2 1116375.VEJY3_08130 7.56e-209 577.0 COG0582@1|root,COG0582@2|Bacteria 2|Bacteria L DNA integration - - - - - - - - - - - - Phage_int_SAM_3,Phage_integrase k141_22782_1 1042377.AFPJ01000037_gene2983 1.7e-71 226.0 COG4520@1|root,COG4520@2|Bacteria,1N0YF@1224|Proteobacteria,1SAAR@1236|Gammaproteobacteria 1236|Gammaproteobacteria M 17 kDa surface antigen - - - - - - - - - - - - 17kDa_Anti_2,Gly-zipper_Omp,Rick_17kDa_Anti,SH3_3 k141_25178_1 218284.CCDN010000005_gene3438 2.19e-123 363.0 COG2056@1|root,COG2056@2|Bacteria,1TSRY@1239|Firmicutes,4HBK6@91061|Bacilli,1ZB9I@1386|Bacillus 91061|Bacilli S antiporter yuiF - - ko:K07084 - - - - ko00000,ko02000 2.A.8.1.12 - iSB619.SA_RS04585 Na_H_antiport_2,Na_H_antiporter k141_21652_1 218284.CCDN010000002_gene2554 4.26e-127 377.0 COG4533@1|root,COG4533@2|Bacteria,1TRY2@1239|Firmicutes,4HBZ3@91061|Bacilli,1ZAUC@1386|Bacillus 91061|Bacilli S Sugar transport-related sRNA regulator N-term - - - - - - - - - - - - SBP_bac_5,SgrR_N k141_13310_2 321846.PS417_23300 4.18e-65 200.0 arCOG12631@1|root,3172B@2|Bacteria,1RH7M@1224|Proteobacteria,1S7J6@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Bacterial PH domain - - - - - - - - - - - - bPH_1 k141_9682_1 218284.CCDN010000012_gene4434 1.42e-172 492.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,4H9V3@91061|Bacilli,1ZC91@1386|Bacillus 91061|Bacilli F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth guaB GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 - - - CBS,IMPDH k141_19200_1 1453501.JELR01000002_gene1092 2.03e-114 333.0 COG0408@1|root,COG0408@2|Bacteria,1MWMF@1224|Proteobacteria,1RMM8@1236|Gammaproteobacteria,464YS@72275|Alteromonadaceae 1236|Gammaproteobacteria H Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX hemF GO:0003674,GO:0003824,GO:0004109,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0016634,GO:0018130,GO:0019438,GO:0030145,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046906,GO:0046914,GO:0046983,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.3.3.3 ko:K00228 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03220 RC00884 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b2436,iBWG_1329.BWG_2198,iECDH10B_1368.ECDH10B_2601,iECDH1ME8569_1439.ECDH1ME8569_2370,iETEC_1333.ETEC_2549,iEcDH1_1363.EcDH1_1225,iEcHS_1320.EcHS_A2573,iEcolC_1368.EcolC_1243,iJO1366.b2436,iJR904.b2436,iY75_1357.Y75_RS12760 Coprogen_oxidas k141_19200_2 1042377.AFPJ01000012_gene1363 1.55e-64 201.0 COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,1S610@1236|Gammaproteobacteria,4677N@72275|Alteromonadaceae 1236|Gammaproteobacteria J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-) CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate tsaC GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061710,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87 ko:K07566 - - R10463 RC00745 ko00000,ko01000,ko03009,ko03016 - - - Sua5_yciO_yrdC k141_302_1 218284.CCDN010000001_gene1742 1.2e-123 354.0 COG0491@1|root,COG0491@2|Bacteria,1TR4H@1239|Firmicutes,4HBXR@91061|Bacilli,1ZDVA@1386|Bacillus 91061|Bacilli S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B k141_35832_1 42565.FP66_05065 1.95e-131 383.0 COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,1RZBQ@1236|Gammaproteobacteria,1XMY0@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the binding-protein-dependent transport system permease family - - - ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 k141_22783_1 218284.CCDN010000002_gene2070 1.32e-76 250.0 COG1199@1|root,COG1199@2|Bacteria,1TPNB@1239|Firmicutes,4HD6T@91061|Bacilli,1ZAUN@1386|Bacillus 91061|Bacilli KL DEAD_2 uvrB3 - 3.1.12.1 ko:K07464 - - - - ko00000,ko01000,ko02048 - - - DEAD,DEAD_2,HBB,Helicase_C_2,PDDEXK_1 k141_6263_1 880073.Calab_1818 1.07e-58 194.0 COG0803@1|root,COG0803@2|Bacteria,2NPH3@2323|unclassified Bacteria 2|Bacteria P Belongs to the bacterial solute-binding protein 9 family znuA - - ko:K02077,ko:K09815,ko:K09818 ko02010,map02010 M00242,M00243,M00244 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 - - ZnuA k141_3822_1 218284.CCDN010000001_gene519 2.27e-136 395.0 COG0538@1|root,COG0538@2|Bacteria,1UHPE@1239|Firmicutes,4H9US@91061|Bacilli,1ZBWV@1386|Bacillus 91061|Bacilli C isocitrate icd - 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh k141_1367_1 1536770.R50345_19185 9.96e-71 225.0 COG1252@1|root,COG1252@2|Bacteria,1UY7H@1239|Firmicutes,4HF9C@91061|Bacilli,26S16@186822|Paenibacillaceae 91061|Bacilli C PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - 1.6.99.3 ko:K03885 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - Pyr_redox_2 k141_1367_2 1536770.R50345_19180 7.11e-99 295.0 COG1595@1|root,COG1595@2|Bacteria,1UZM5@1239|Firmicutes,4HEK0@91061|Bacilli,26SC7@186822|Paenibacillaceae 91061|Bacilli K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_15689_1 218284.CCDN010000001_gene224 3.82e-100 296.0 2E5MF@1|root,330CC@2|Bacteria,1VEG0@1239|Firmicutes,4HMVE@91061|Bacilli,1ZBQY@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2953) ytfI - - - - - - - - - - - DUF2953 k141_9683_1 1294265.JCM21738_1618 1.01e-81 254.0 COG3434@1|root,COG3434@2|Bacteria,1TPWC@1239|Firmicutes,4HD4Q@91061|Bacilli,1ZDNG@1386|Bacillus 91061|Bacilli T signal transduction protein containing EAL and modified HD-GYP domains yuxH - - - - - - - - - - - EAL,HDOD k141_26427_1 218284.CCDN010000001_gene980 1.09e-68 227.0 COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,4HADT@91061|Bacilli,1ZAZA@1386|Bacillus 91061|Bacilli KT Transcriptional regulator bkdR - - - - - - - - - - - DapB_N,HTH_8,PAS,Sigma54_activat k141_10873_1 1461580.CCAS010000082_gene4283 1.55e-65 205.0 COG1335@1|root,COG1335@2|Bacteria,1V2DX@1239|Firmicutes,4HJMV@91061|Bacilli,1ZGBB@1386|Bacillus 91061|Bacilli Q Isochorismatase family yaaI - - - - - - - - - - - Isochorismatase k141_10873_2 796606.BMMGA3_00110 6.37e-96 291.0 COG1388@1|root,COG3858@1|root,COG1388@2|Bacteria,COG3858@2|Bacteria,1TQK2@1239|Firmicutes,4HBJC@91061|Bacilli,1ZBQC@1386|Bacillus 91061|Bacilli M Glycoside Hydrolase Family yaaH - - ko:K06306 - - - - ko00000 - - - Glyco_hydro_18,LysM k141_21653_1 1112212.JH584235_gene3557 0.00046 45.8 COG1629@1|root,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,2TTJG@28211|Alphaproteobacteria,2JZUI@204457|Sphingomonadales 204457|Sphingomonadales P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec k141_33480_1 2340.JV46_20340 3.11e-30 123.0 COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,1RMUH@1236|Gammaproteobacteria,1J62R@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C NADH-quinone oxidoreductase nuoG - 1.6.5.3 ko:K00336 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Fer2_4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3 k141_32230_1 218284.CCDN010000001_gene1808 6.38e-190 553.0 COG0249@1|root,COG0249@2|Bacteria,1TPRJ@1239|Firmicutes,4HA63@91061|Bacilli,1ZB93@1386|Bacillus 91061|Bacilli L that it carries out the mismatch recognition step. This protein has a weak ATPase activity mutS GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K03555 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V k141_4936_1 218284.CCDN010000012_gene4443 1.28e-27 104.0 COG1335@1|root,COG1335@2|Bacteria,1V2DX@1239|Firmicutes,4HJMV@91061|Bacilli,1ZGBB@1386|Bacillus 91061|Bacilli Q Isochorismatase family yaaI - - - - - - - - - - - Isochorismatase k141_4936_2 218284.CCDN010000012_gene4444 1.47e-83 249.0 COG0590@1|root,COG0590@2|Bacteria,1V3HZ@1239|Firmicutes,4HH7S@91061|Bacilli,1ZFRP@1386|Bacillus 91061|Bacilli FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) tadA GO:0002097,GO:0002100,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 3.5.4.33 ko:K11991 - - R10223 RC00477 ko00000,ko01000,ko03016 - - - MafB19-deam k141_2623_1 1279017.AQYJ01000029_gene3473 1.83e-26 102.0 COG1309@1|root,COG1309@2|Bacteria,1N6TK@1224|Proteobacteria,1SCNY@1236|Gammaproteobacteria,4692V@72275|Alteromonadaceae 1236|Gammaproteobacteria K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N k141_3823_1 1294265.JCM21738_4671 4.5e-78 239.0 COG0784@1|root,COG0835@1|root,COG0784@2|Bacteria,COG0835@2|Bacteria,1TRJU@1239|Firmicutes,4HCPT@91061|Bacilli,1ZAYA@1386|Bacillus 91061|Bacilli T Chemotaxis protein CheV cheV GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0044424,GO:0044444,GO:0044464,GO:0050896 - ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - CheW,Response_reg k141_18108_1 218284.CCDN010000005_gene3302 4.58e-259 724.0 COG0475@1|root,COG0569@1|root,COG0475@2|Bacteria,COG0569@2|Bacteria,1TS32@1239|Firmicutes,4H9Q5@91061|Bacilli,1ZBJR@1386|Bacillus 91061|Bacilli P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family yjbQ - - ko:K03455,ko:K03499 - - - - ko00000,ko02000 2.A.37,2.A.38.1,2.A.38.4 - - Na_H_Exchanger,TrkA_C,TrkA_N k141_22785_1 1042377.AFPJ01000019_gene2533 1.8e-69 224.0 COG4242@1|root,COG4242@2|Bacteria,1PR9J@1224|Proteobacteria,1RVJH@1236|Gammaproteobacteria,469D6@72275|Alteromonadaceae 1236|Gammaproteobacteria PQ Peptidase family S51 cphB - 3.4.15.6 ko:K13282 - - R09722 RC00064,RC00141 ko00000,ko01000,ko01002 - - - Peptidase_S51 k141_304_1 1169144.KB910931_gene932 1.7e-52 172.0 COG0154@1|root,COG0154@2|Bacteria,1TRFI@1239|Firmicutes,4HBZA@91061|Bacilli,1ZCZT@1386|Bacillus 91061|Bacilli J COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases gatA1 - 3.5.1.4 ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 - R02540,R03096,R03180,R03909,R05551,R05590 RC00010,RC00100,RC00950,RC01025 ko00000,ko00001,ko01000 - - - Amidase k141_304_2 1384057.CD33_03440 4.54e-24 100.0 COG2409@1|root,COG2409@2|Bacteria,1TQ7C@1239|Firmicutes,4H9XX@91061|Bacilli,3IW97@400634|Lysinibacillus 91061|Bacilli S MMPL family - - - ko:K06994 - - - - ko00000 - - - MMPL k141_26428_2 1294265.JCM21738_1462 5.81e-79 239.0 COG3403@1|root,COG3403@2|Bacteria,1US5K@1239|Firmicutes,4HEQ9@91061|Bacilli,1ZDEK@1386|Bacillus 91061|Bacilli S YqcI/YcgG family - - - ko:K09190 - - - - ko00000 - - - YqcI_YcgG k141_34664_2 1116375.VEJY3_01525 0.0 1823.0 COG2911@1|root,COG2911@2|Bacteria,1MUVD@1224|Proteobacteria,1RMMF@1236|Gammaproteobacteria,1XV86@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria - - - ko:K09800 - - - - ko00000,ko02000 - - - TamB k141_7360_1 1453501.JELR01000002_gene1487 1.97e-56 179.0 COG1225@1|root,COG1225@2|Bacteria,1RER0@1224|Proteobacteria,1S4K1@1236|Gammaproteobacteria,46AJ1@72275|Alteromonadaceae 1236|Gammaproteobacteria O Redoxin - - 1.11.1.15 ko:K03564 - - - - ko00000,ko01000 - - - AhpC-TSA k141_28794_2 218284.CCDN010000001_gene516 1.28e-23 98.6 COG0628@1|root,COG0628@2|Bacteria,1TS4S@1239|Firmicutes,4HC6G@91061|Bacilli,1ZBXK@1386|Bacillus 91061|Bacilli S sporulation integral membrane protein YtvI ytvI GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - - - - - - - - - - AI-2E_transport k141_6265_1 218284.CCDN010000005_gene3491 2.02e-29 122.0 COG1173@1|root,COG1173@2|Bacteria,1V21B@1239|Firmicutes,4HG7B@91061|Bacilli,1ZR0T@1386|Bacillus 91061|Bacilli EP Binding-protein-dependent transport system inner membrane component - - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 k141_26429_1 1403313.AXBR01000018_gene3521 7.3e-55 182.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,1ZB7V@1386|Bacillus 91061|Bacilli I Belongs to the thiolase family - - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N k141_26429_2 986075.CathTA2_1194 4.89e-25 102.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli 91061|Bacilli I Belongs to the thiolase family thlA_2 - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N k141_18109_1 1307436.PBF_02230 4.57e-40 142.0 COG4927@1|root,COG4927@2|Bacteria,1TQGX@1239|Firmicutes,4HATV@91061|Bacilli,1ZC2P@1386|Bacillus 91061|Bacilli S Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase - - - - - - - - - - - - AAT k141_18109_2 1499685.CCFJ01000012_gene1808 3.96e-15 72.4 29WZP@1|root,30IMY@2|Bacteria,1V55T@1239|Firmicutes,4HI9P@91061|Bacilli,1ZH8I@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_15690_1 1250278.JQNQ01000001_gene3254 0.000846 48.5 COG3391@1|root,COG3391@2|Bacteria 2|Bacteria CO amine dehydrogenase activity - - - - - - - - - - - - CHU_C,Reprolysin_4,TSP_3 k141_20356_1 236097.ADG881_115 2.75e-143 419.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RNGU@1236|Gammaproteobacteria,1XJQ1@135619|Oceanospirillales 135619|Oceanospirillales I Belongs to the thiolase family - - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N k141_37019_1 1453501.JELR01000002_gene849 1.14e-135 411.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MV8W@1224|Proteobacteria,1RMQA@1236|Gammaproteobacteria,46619@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec k141_3825_2 283699.D172_2759 3.06e-19 87.8 COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,2Q0K4@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria M Gamma-glutamyltranspeptidase ggt_3 - 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept k141_21654_1 218284.CCDN010000002_gene2165 3.24e-165 479.0 COG0025@1|root,COG0025@2|Bacteria,1U8X3@1239|Firmicutes,4HBQR@91061|Bacilli,1ZQCD@1386|Bacillus 91061|Bacilli P Sodium/hydrogen exchanger family - - - - - - - - - - - - Na_H_Exchanger,TrkA_N k141_23972_2 986075.CathTA2_0864 5.62e-14 71.2 COG0584@1|root,COG0584@2|Bacteria,1TQ3Y@1239|Firmicutes,4HAI9@91061|Bacilli 91061|Bacilli C glycerophosphoryl diester phosphodiesterase - - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - GDPD k141_19202_1 1453501.JELR01000002_gene1336 6.35e-15 74.3 COG0823@1|root,COG0823@2|Bacteria,1R3VN@1224|Proteobacteria,1RNKG@1236|Gammaproteobacteria,46408@72275|Alteromonadaceae 1236|Gammaproteobacteria U COG0823 Periplasmic component of the Tol biopolymer transport system - - - - - - - - - - - - PD40 k141_19202_2 1453501.JELR01000002_gene1335 1.33e-44 155.0 28HN6@1|root,2Z7WJ@2|Bacteria,1R5QB@1224|Proteobacteria,1RNJN@1236|Gammaproteobacteria,4667S@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_33481_1 315730.BcerKBAB4_2939 0.000465 47.4 2E1ID@1|root,32R97@2|Bacteria,1V7YN@1239|Firmicutes,4HIZS@91061|Bacilli,1ZHRN@1386|Bacillus 91061|Bacilli S Domain of Unknown Function (DUF1259) - - - - - - - - - - - - DUF1529 k141_34665_1 865861.AZSU01000008_gene667 3.8e-25 108.0 COG2199@1|root,COG3706@2|Bacteria,1V9Y7@1239|Firmicutes,24A8B@186801|Clostridia,36E8P@31979|Clostridiaceae 186801|Clostridia T Diguanylate cyclase - - - - - - - - - - - - AAA_16,GGDEF,Pkinase,TPR_12,TPR_8 k141_10876_1 218284.CCDN010000001_gene1818 6.57e-166 471.0 COG0167@1|root,COG1146@1|root,COG0167@2|Bacteria,COG1146@2|Bacteria,1TRPI@1239|Firmicutes,4HBRG@91061|Bacilli,1ZD6D@1386|Bacillus 91061|Bacilli CF dihydroorotate dehydrogenase preA - 1.3.1.1 ko:K17723 ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100 M00046 R00977,R01414,R11026 RC00072,RC00123 ko00000,ko00001,ko00002,ko01000 - - - DHO_dh,Fer4_21 k141_15691_1 1267535.KB906767_gene54 2.11e-18 89.4 COG0176@1|root,COG0176@2|Bacteria,3Y6V9@57723|Acidobacteria 57723|Acidobacteria H Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway - - 2.2.1.2 ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01827 RC00439,RC00604 ko00000,ko00001,ko00002,ko01000 - - - TAL_FSA k141_9700_1 945550.VISI1226_19961 1.11e-196 553.0 COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,1RMZD@1236|Gammaproteobacteria,1XTSW@135623|Vibrionales 135623|Vibrionales E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine hisD GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01158,R01163,R03012 RC00099,RC00242,RC00463 ko00000,ko00001,ko00002,ko01000 - - - Histidinol_dh k141_13338_1 42565.FP66_10950 6.46e-108 317.0 COG4977@1|root,COG4977@2|Bacteria 2|Bacteria K sequence-specific DNA binding cdhR - - ko:K17736 - - - - ko00000,ko03000 - - - DJ-1_PfpI,HTH_18 k141_34692_1 1279017.AQYJ01000029_gene3464 2.17e-24 107.0 COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,1RMPT@1236|Gammaproteobacteria,464DD@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG3209 Rhs family protein - - - - - - - - - - - - RHS_repeat,SpvB,TcdB_toxin_midN,VCBS k141_20366_1 1279017.AQYJ01000029_gene3836 0.0 998.0 COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,1RM9A@1236|Gammaproteobacteria,4647U@72275|Alteromonadaceae 1236|Gammaproteobacteria D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins ftsK GO:0000920,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006950,GO:0006970,GO:0007059,GO:0008094,GO:0008150,GO:0009628,GO:0009651,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0015616,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0033676,GO:0042221,GO:0042623,GO:0042802,GO:0043085,GO:0043565,GO:0044093,GO:0044425,GO:0044459,GO:0044464,GO:0045893,GO:0045935,GO:0046677,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051301,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0070887,GO:0071236,GO:0071944,GO:0080090,GO:0097159,GO:0140097,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma k141_20366_2 1042377.AFPJ01000007_gene1783 2.48e-103 303.0 COG2834@1|root,COG2834@2|Bacteria,1PXDV@1224|Proteobacteria,1S9FW@1236|Gammaproteobacteria,46853@72275|Alteromonadaceae 1236|Gammaproteobacteria M Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) lolA GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0030288,GO:0030313,GO:0031975,GO:0032940,GO:0033036,GO:0034613,GO:0042597,GO:0042886,GO:0042953,GO:0042954,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0051641,GO:0070727,GO:0071702,GO:0071705,GO:0072321,GO:0072322,GO:0072323,GO:0072657 - ko:K03634 - - - - ko00000 - - - LolA k141_23988_1 218284.CCDN010000007_gene3954 1.29e-162 473.0 COG0247@1|root,COG2181@1|root,COG0247@2|Bacteria,COG2181@2|Bacteria,1TPG1@1239|Firmicutes,4HB2J@91061|Bacilli,1ZBAJ@1386|Bacillus 91061|Bacilli C COG0247 Fe-S oxidoreductase ywjF - - - - - - - - - - - CCG,Fer4_8 k141_29894_1 1211844.CBLM010000003_gene2562 1.34e-05 50.8 COG0793@1|root,COG0793@2|Bacteria,1TPBI@1239|Firmicutes,3VPKZ@526524|Erysipelotrichia 526524|Erysipelotrichia M Belongs to the peptidase S41A family - - 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - PDZ_2,PG_binding_1,Peptidase_S41 k141_22804_1 1049564.TevJSym_am00390 8.46e-47 172.0 COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,1RPV3@1236|Gammaproteobacteria,1J5C9@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria NU COG3419 Tfp pilus assembly protein, tip-associated adhesin PilY1 pilY1 - - ko:K02674 - - - - ko00000,ko02035,ko02044 - - - Neisseria_PilC k141_13339_2 1423321.AS29_15760 3.31e-33 122.0 COG2755@1|root,COG2755@2|Bacteria,1V1QW@1239|Firmicutes,4HGWC@91061|Bacilli,1ZGV5@1386|Bacillus 91061|Bacilli E GDSL-like Lipase/Acylhydrolase - - - - - - - - - - - - Lipase_GDSL_2 k141_9701_1 218284.CCDN010000001_gene1870 9.65e-62 212.0 COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,4H9WA@91061|Bacilli,1ZANX@1386|Bacillus 91061|Bacilli D Belongs to the FtsK SpoIIIE SftA family ftsK GO:0000003,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma k141_334_2 218284.CCDN010000007_gene4000 7.98e-97 287.0 COG0224@1|root,COG0224@2|Bacteria,1TPBX@1239|Firmicutes,4HB0E@91061|Bacilli,1ZCKT@1386|Bacillus 91061|Bacilli C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex atpG - - ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - iSB619.SA_RS10970,iYO844.BSU36820 ATP-synt k141_1387_1 1279017.AQYJ01000027_gene1665 5.56e-130 376.0 COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,1RR68@1236|Gammaproteobacteria,464NZ@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate moaA GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016829,GO:0016830,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0061798,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.22 ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09394 RC03420 ko00000,ko00001,ko01000 - - iSbBS512_1146.SbBS512_E2571,ic_1306.c0862 Fer4_12,Mob_synth_C,Radical_SAM k141_25203_3 1279017.AQYJ01000027_gene1812 2.83e-55 175.0 COG3312@1|root,COG3312@2|Bacteria,1N777@1224|Proteobacteria,1SD0Z@1236|Gammaproteobacteria,468Z4@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG3312 F0F1-type ATP synthase, subunit I atpI GO:0003674,GO:0003824,GO:0005215,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044769,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02116 - - - - ko00000,ko00194 3.A.2.1 - - ATP-synt_I k141_25203_4 1453501.JELR01000002_gene1124 4e-166 470.0 COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,1RN65@1236|Gammaproteobacteria,4649M@72275|Alteromonadaceae 1236|Gammaproteobacteria K Belongs to the ParB family parB - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc k141_25203_5 1042377.AFPJ01000012_gene1335 4.59e-154 437.0 COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,1RNJK@1236|Gammaproteobacteria,464DZ@72275|Alteromonadaceae 1236|Gammaproteobacteria D COG1192 ATPases involved in chromosome partitioning parA - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 k141_25203_6 1279017.AQYJ01000027_gene1809 8.01e-106 310.0 COG0357@1|root,COG0357@2|Bacteria,1MY0K@1224|Proteobacteria,1RMRZ@1236|Gammaproteobacteria,466SB@72275|Alteromonadaceae 1236|Gammaproteobacteria J Specifically methylates the N7 position of guanine in position 527 of 16S rRNA rsmG GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 ko:K03501 - - - - ko00000,ko01000,ko03009,ko03036 - - - GidB k141_2650_1 365528.KB891228_gene257 3.58e-144 426.0 COG0044@1|root,COG0044@2|Bacteria,2IAM1@201174|Actinobacteria,4ETRX@85013|Frankiales 201174|Actinobacteria F allantoinase - - 3.5.2.5 ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 M00546 R02425 RC00680 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 k141_2650_2 1304275.C41B8_01075 2.25e-21 90.9 COG1188@1|root,COG1188@2|Bacteria,1MZR6@1224|Proteobacteria,1S8VU@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Belongs to the HSP15 family hslR GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003727,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009451,GO:0009628,GO:0009987,GO:0016070,GO:0033554,GO:0034605,GO:0034641,GO:0043021,GO:0043023,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - ko:K04762 - - - - ko00000,ko03110 - - - S4 k141_2650_3 1121904.ARBP01000005_gene4611 1.31e-28 108.0 COG0135@1|root,COG0135@2|Bacteria,4NK5D@976|Bacteroidetes,47NUD@768503|Cytophagia 976|Bacteroidetes E N-(5'phosphoribosyl)anthranilate (PRA) isomerase - - 5.3.1.24 ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03509 RC00945 ko00000,ko00001,ko00002,ko01000 - - - PRAI k141_32244_2 1196031.ALEG01000039_gene1833 8.78e-58 182.0 2F7CQ@1|root,33ZTS@2|Bacteria 2|Bacteria S Bacteriophage holin family - - - - - - - - - - - - Phage_holin_4_1 k141_32244_3 218284.CCDN010000001_gene926 7.03e-55 182.0 COG0860@1|root,COG0860@2|Bacteria,1U9U9@1239|Firmicutes,4HQTP@91061|Bacilli,1ZMYG@1386|Bacillus 91061|Bacilli M Ami_3 - - - - - - - - - - - - Amidase_3 k141_31188_1 1279017.AQYJ01000018_gene780 4.26e-76 231.0 COG1546@1|root,COG1546@2|Bacteria,1RH2Y@1224|Proteobacteria,1S5WH@1236|Gammaproteobacteria,4677Y@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the CinA family ygaD GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016811,GO:0019159 3.5.1.42 ko:K03743 ko00760,map00760 - R02322 RC00100 ko00000,ko00001,ko01000 - - - CinA k141_18129_1 218284.CCDN010000001_gene878 3.18e-192 552.0 COG0840@1|root,COG0840@2|Bacteria,1UHRW@1239|Firmicutes,4IS7R@91061|Bacilli,1ZS21@1386|Bacillus 91061|Bacilli NT nuclear chromosome segregation - - - - - - - - - - - - Peptidase_S74 k141_18129_5 218284.CCDN010000001_gene925 1.9e-11 60.8 2ERH2@1|root,33J2J@2|Bacteria,1VP49@1239|Firmicutes,4HSDF@91061|Bacilli,1ZJEW@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - Holin_SPP1 k141_28814_1 1279017.AQYJ01000024_gene1059 7.48e-38 139.0 COG1485@1|root,COG1485@2|Bacteria,1MUUW@1224|Proteobacteria,1RMTJ@1236|Gammaproteobacteria,464WH@72275|Alteromonadaceae 1236|Gammaproteobacteria D Reduces the stability of FtsZ polymers in the presence of ATP zapE GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032153,GO:0044424,GO:0044464,GO:0051301 - ko:K06916 - - - - ko00000,ko03036 - - - AFG1_ATPase k141_28814_2 1453501.JELR01000001_gene3072 1.99e-71 218.0 COG3105@1|root,COG3105@2|Bacteria,1N25P@1224|Proteobacteria,1SE1A@1236|Gammaproteobacteria,468Q0@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria - - - ko:K09908 - - - - ko00000 - - - DUF1043 k141_2669_2 1463879.JOHP01000028_gene4868 1.7e-05 46.6 COG0691@1|root,COG0691@2|Bacteria,2GJX1@201174|Actinobacteria 201174|Actinobacteria O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA smpB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K03664 - - - - ko00000 - - - SmpB k141_9732_1 1423321.AS29_06680 5.02e-13 68.6 COG2267@1|root,COG2267@2|Bacteria,1V1Y6@1239|Firmicutes,4HFW7@91061|Bacilli,1ZDTZ@1386|Bacillus 91061|Bacilli I Ndr family pcaD - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 k141_16910_1 171693.BN988_02234 1.04e-145 430.0 COG1874@1|root,COG1874@2|Bacteria,1TQN6@1239|Firmicutes,4IC6C@91061|Bacilli,23MZ3@182709|Oceanobacillus 91061|Bacilli G Beta-galactosidase trimerisation domain - - - - - - - - - - - - Glyco_hydro_42,Glyco_hydro_42M k141_26529_1 1453501.JELR01000005_gene1589 6.77e-68 224.0 COG0366@1|root,COG0366@2|Bacteria,1MU90@1224|Proteobacteria,1RQ1S@1236|Gammaproteobacteria,465MB@72275|Alteromonadaceae 1236|Gammaproteobacteria G Alpha-amylase domain malS GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0004556,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009311,GO:0009313,GO:0009987,GO:0016052,GO:0016160,GO:0016787,GO:0016798,GO:0030288,GO:0030313,GO:0030978,GO:0030980,GO:0031975,GO:0042597,GO:0043167,GO:0043169,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044464,GO:0046872,GO:0051691,GO:0051692,GO:0071704,GO:1901575 3.2.1.1 ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 - R02108,R02112,R11262 - ko00000,ko00001,ko01000 - GH13 iECABU_c1320.ECABU_c40140,iECP_1309.ECP_3675,iECSE_1348.ECSE_3847,iPC815.YPO4080,ic_1306.c4392 Alpha-amylase k141_32257_1 1294265.JCM21738_1861 3.11e-107 327.0 COG0457@1|root,COG0457@2|Bacteria,1UATF@1239|Firmicutes,4HE1D@91061|Bacilli,1ZBPM@1386|Bacillus 91061|Bacilli S ATPase. Has a role at an early stage in the morphogenesis of the spore coat - - - - - - - - - - - - Dynamin_N,TPR_8 k141_19244_1 666686.B1NLA3E_10865 3.53e-96 288.0 COG0010@1|root,COG0010@2|Bacteria,1TP2A@1239|Firmicutes,4HCKQ@91061|Bacilli,1ZBPI@1386|Bacillus 91061|Bacilli E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide hutG - 3.5.3.8 ko:K01479 ko00340,ko01100,map00340,map01100 M00045 R02285 RC00221,RC00681 ko00000,ko00001,ko00002,ko01000 - - - Arginase k141_4972_1 1042377.AFPJ01000005_gene2446 5.6e-142 419.0 COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,1RNVR@1236|Gammaproteobacteria,465MZ@72275|Alteromonadaceae 1236|Gammaproteobacteria P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family kefC - - ko:K03455,ko:K11745,ko:K11747 - - - - ko00000,ko02000 2.A.37,2.A.37.1.1,2.A.37.1.2 - - Na_H_Exchanger,TrkA_N k141_12204_1 218284.CCDN010000007_gene3818 5.78e-139 402.0 COG0104@1|root,COG0104@2|Bacteria,1TQ4C@1239|Firmicutes,4H9YT@91061|Bacilli,1ZBF8@1386|Bacillus 91061|Bacilli F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP purA GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 - - - Adenylsucc_synt k141_15730_1 218284.CCDN010000006_gene3597 8.4e-29 105.0 COG3462@1|root,COG3462@2|Bacteria,1VKBD@1239|Firmicutes,4IJWA@91061|Bacilli,1ZJXM@1386|Bacillus 91061|Bacilli S Short C-terminal domain - - - ko:K08982 - - - - ko00000 - - - SHOCT k141_15730_2 218284.CCDN010000006_gene3596 2.28e-31 122.0 COG2132@1|root,COG2132@2|Bacteria,1TQJK@1239|Firmicutes,4IRUW@91061|Bacilli,1ZBEQ@1386|Bacillus 91061|Bacilli Q Multi-copper - - - - - - - - - - - - Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3,Cupredoxin_1 k141_6335_1 1453501.JELR01000005_gene1596 2.12e-149 442.0 COG0366@1|root,COG0366@2|Bacteria,1NUIZ@1224|Proteobacteria,1RPMQ@1236|Gammaproteobacteria,465DG@72275|Alteromonadaceae 1236|Gammaproteobacteria G Alpha amylase, catalytic domain - - 2.4.1.19 ko:K00701 ko00500,map00500 - R11260 - ko00000,ko00001,ko01000 - CBM20,GH13 - Alpha-amylase k141_31217_1 1385513.N780_08145 5.9e-113 338.0 COG1292@1|root,COG1292@2|Bacteria,1TRS6@1239|Firmicutes,4HA7U@91061|Bacilli,2Y8QZ@289201|Pontibacillus 91061|Bacilli U Belongs to the BCCT transporter (TC 2.A.15) family - - - - - - - - - - - - BCCT k141_19277_1 218284.CCDN010000007_gene3980 4.64e-39 137.0 COG2890@1|root,COG2890@2|Bacteria,1TSMA@1239|Firmicutes,4HC6W@91061|Bacilli,1ZBSE@1386|Bacillus 91061|Bacilli J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif prmC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 ko:K02493 - - R10806 RC00003,RC03279 ko00000,ko01000,ko03012 - - - MTS k141_16955_1 1453501.JELR01000002_gene495 1.25e-118 349.0 COG0457@1|root,COG0457@2|Bacteria,1PNM7@1224|Proteobacteria,1RXYT@1236|Gammaproteobacteria,46D2N@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0457 FOG TPR repeat - - - - - - - - - - - - Alkyl_sulf_dimr,TPR_19,TPR_8 k141_375_1 218284.CCDN010000001_gene1425 1.71e-238 680.0 COG4581@1|root,COG4581@2|Bacteria,1TRYX@1239|Firmicutes,4HU79@91061|Bacilli,1ZE6K@1386|Bacillus 91061|Bacilli L COG0513 Superfamily II DNA and RNA helicases - - 3.6.4.13 ko:K17675 - - - - ko00000,ko01000,ko03029 - - - Helicase_C k141_16956_1 1042377.AFPJ01000024_gene822 9.88e-43 141.0 COG3027@1|root,COG3027@2|Bacteria,1N6YN@1224|Proteobacteria,1SCBI@1236|Gammaproteobacteria,468PG@72275|Alteromonadaceae 1236|Gammaproteobacteria D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division zapA GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000921,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0030428,GO:0031106,GO:0032153,GO:0032185,GO:0032505,GO:0032506,GO:0034622,GO:0042802,GO:0043093,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0051301,GO:0061640,GO:0065003,GO:0070925,GO:0071840,GO:0090529,GO:1902410,GO:1903047 - ko:K09888 - - - - ko00000,ko03036 - - - ZapA k141_16956_2 1453501.JELR01000002_gene700 2.86e-31 111.0 2C0ET@1|root,33A9M@2|Bacteria,1NGE5@1224|Proteobacteria,1SGID@1236|Gammaproteobacteria,4697N@72275|Alteromonadaceae 1236|Gammaproteobacteria S TIGRFAM TIGR02449 family protein VL23_04670 - - ko:K09892 - - - - ko00000,ko03036 - - - - k141_26566_2 1453501.JELR01000001_gene2315 1.74e-48 173.0 COG2366@1|root,COG2366@2|Bacteria,1MVMH@1224|Proteobacteria,1RPRP@1236|Gammaproteobacteria,464U8@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG2366 Protein related to penicillin acylase quiP - 3.5.1.11,3.5.1.97 ko:K01434,ko:K07116 ko00311,ko01130,map00311,map01130 - R02170 RC00166,RC00328 ko00000,ko00001,ko01000,ko01002 - - - Penicil_amidase k141_5003_2 218284.CCDN010000002_gene1995 3.55e-132 390.0 COG1001@1|root,COG1001@2|Bacteria,1TP84@1239|Firmicutes,4HAIR@91061|Bacilli,1ZAY2@1386|Bacillus 91061|Bacilli F adenine deaminase yerA GO:0003674,GO:0003824,GO:0006040,GO:0006044,GO:0006046,GO:0008150,GO:0008152,GO:0008448,GO:0009056,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0046348,GO:0071704,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901575 3.5.4.2 ko:K01486 ko00230,ko01100,map00230,map01100 - R01244 RC00477 ko00000,ko00001,ko01000 - - - Adenine_deam_C,Amidohydro_1 k141_20410_1 469595.CSAG_01328 0.000117 45.4 COG1396@1|root,COG1396@2|Bacteria,1N0DX@1224|Proteobacteria,1S8KX@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator - - - - - - - - - - - - HTH_3 k141_28862_1 1453501.JELR01000001_gene2411 3.62e-274 766.0 COG1765@1|root,COG1944@1|root,COG1765@2|Bacteria,COG1944@2|Bacteria,1MV7K@1224|Proteobacteria,1RN47@1236|Gammaproteobacteria,464WG@72275|Alteromonadaceae 1236|Gammaproteobacteria O redox protein, regulator of disulfide bond formation ycaO GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018193,GO:0018197,GO:0018198,GO:0018339,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0047429,GO:0047693,GO:0071704,GO:1901564 - ko:K09136 - - - - ko00000,ko03009 - - - OsmC,YcaO k141_10949_1 1122194.AUHU01000004_gene1446 1.55e-84 263.0 COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,1RPZC@1236|Gammaproteobacteria,465AN@72275|Alteromonadaceae 1236|Gammaproteobacteria J exonuclease of the beta-lactamase fold involved in RNA processing - - - ko:K07576 - - - - ko00000 - - - Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL k141_10949_2 1279017.AQYJ01000021_gene2802 1.85e-132 380.0 COG0593@1|root,COG0593@2|Bacteria,1MVW6@1224|Proteobacteria,1RPJP@1236|Gammaproteobacteria,46796@72275|Alteromonadaceae 1236|Gammaproteobacteria L Belongs to the DnaA family. HdA subfamily hda GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006275,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008156,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030174,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1901576,GO:2000104,GO:2000112,GO:2000113 - ko:K10763 - - - - ko00000,ko03032 - - - Bac_DnaA k141_10949_3 1279017.AQYJ01000021_gene2801 4.5e-158 455.0 COG3249@1|root,COG3249@2|Bacteria,1N0PD@1224|Proteobacteria,1S9C4@1236|Gammaproteobacteria,466SQ@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria VV2512 - - ko:K09938 - - - - ko00000 - - - DUF2066 k141_10949_5 1026970.XP_008834168.1 5.92e-16 79.7 COG0151@1|root,COG0299@1|root,KOG0237@2759|Eukaryota,KOG3076@2759|Eukaryota,38BPB@33154|Opisthokonta,3BDXA@33208|Metazoa,3CXAA@33213|Bilateria,4819S@7711|Chordata,48WR7@7742|Vertebrata,3JB9Y@40674|Mammalia,35IPU@314146|Euarchontoglires,4PT9U@9989|Rodentia 33208|Metazoa F Trifunctional purine biosynthetic protein adenosine-3 GART GO:0001505,GO:0003674,GO:0003824,GO:0004637,GO:0004641,GO:0004644,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006144,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006520,GO:0006544,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006760,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009069,GO:0009108,GO:0009112,GO:0009113,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009396,GO:0009987,GO:0010033,GO:0010035,GO:0016053,GO:0016740,GO:0016741,GO:0016742,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0034641,GO:0034654,GO:0042133,GO:0042221,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046040,GO:0046112,GO:0046148,GO:0046390,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0065007,GO:0065008,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.1.2.2,6.3.3.1,6.3.4.13 ko:K11787 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R04144,R04208,R04325,R04326 RC00026,RC00090,RC00166,RC00197,RC01100,RC01128 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C,Formyl_trans_N,GARS_A,GARS_C,GARS_N k141_12239_1 398511.BpOF4_09765 4.51e-62 194.0 2DZZA@1|root,32VNW@2|Bacteria,1VDGJ@1239|Firmicutes,4HNGY@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - k141_3888_3 1209072.ALBT01000033_gene1573 0.0001 43.5 2EH0V@1|root,32J0Z@2|Bacteria,1PCAJ@1224|Proteobacteria,1SX7I@1236|Gammaproteobacteria,1FHR9@10|Cellvibrio 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_9762_1 796606.BMMGA3_10250 8.86e-72 225.0 29PIZ@1|root,30AH4@2|Bacteria,1VJKE@1239|Firmicutes,4HI1K@91061|Bacilli,1ZDJM@1386|Bacillus 91061|Bacilli - - - - 3.4.24.89 ko:K20109 - - - - ko00000,ko01000,ko01002 - - - ATLF k141_22892_1 1042377.AFPJ01000032_gene2700 3.12e-179 506.0 COG0524@1|root,COG0524@2|Bacteria,1MUUC@1224|Proteobacteria,1RMN2@1236|Gammaproteobacteria,464Y8@72275|Alteromonadaceae 1236|Gammaproteobacteria G pfkB family carbohydrate kinase gsk GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008906,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237 2.7.1.15,2.7.1.4,2.7.1.73 ko:K00847,ko:K00852,ko:K00892 ko00030,ko00051,ko00230,ko00500,ko00520,ko01100,map00030,map00051,map00230,map00500,map00520,map01100 - R00760,R00867,R01051,R01131,R01228,R02750,R03920 RC00002,RC00017 ko00000,ko00001,ko01000 - - iSDY_1059.SDY_0442 PfkB k141_1419_1 218284.CCDN010000004_gene3096 1.54e-19 80.9 2BAGI@1|root,323X4@2|Bacteria,1UARE@1239|Firmicutes,4IM44@91061|Bacilli,1ZJ3I@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3889) - - - - - - - - - - - - DUF3889 k141_19278_2 1116375.VEJY3_04155 7.18e-198 549.0 COG0395@1|root,COG0395@2|Bacteria,1MUT9@1224|Proteobacteria,1RZHT@1236|Gammaproteobacteria,1XTKM@135623|Vibrionales 135623|Vibrionales P COG0395 ABC-type sugar transport system, permease component - - - ko:K17317 ko02010,map02010 M00605 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.24,3.A.1.1.30 - - BPD_transp_1 k141_16958_1 218284.CCDN010000002_gene2162 9.78e-128 373.0 COG5520@1|root,COG5520@2|Bacteria,1TS99@1239|Firmicutes,4HEUA@91061|Bacilli,1ZF3X@1386|Bacillus 91061|Bacilli M Belongs to the glycosyl hydrolase 30 family - - 3.2.1.45 ko:K01201 ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142 - R01498 RC00059,RC00451 ko00000,ko00001,ko01000 - GH30 - Glyco_hydro_30,Glyco_hydro_30C k141_3889_1 1042377.AFPJ01000020_gene2098 1.14e-82 262.0 COG2067@1|root,COG2067@2|Bacteria,1MUU4@1224|Proteobacteria,1RQZJ@1236|Gammaproteobacteria,465E0@72275|Alteromonadaceae 1236|Gammaproteobacteria I Long-chain fatty acid fadL GO:0003674,GO:0005215,GO:0005319,GO:0005324,GO:0005342,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006820,GO:0006869,GO:0008028,GO:0008150,GO:0008509,GO:0008514,GO:0009279,GO:0010876,GO:0015075,GO:0015245,GO:0015267,GO:0015288,GO:0015318,GO:0015483,GO:0015711,GO:0015718,GO:0015849,GO:0015908,GO:0015909,GO:0016020,GO:0019867,GO:0022803,GO:0022829,GO:0022834,GO:0022836,GO:0022857,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0034220,GO:0044462,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098656,GO:1903825,GO:1905039 - ko:K06076 - - - - ko00000,ko02000 1.B.9 - iECs_1301.ECs3227,iG2583_1286.G2583_2880,iZ_1308.Z3608 Toluene_X k141_31218_1 42565.FP66_02110 2.04e-129 370.0 COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,1RN4H@1236|Gammaproteobacteria,1XHWY@135619|Oceanospirillales 135619|Oceanospirillales L exodeoxyribonuclease III - - 3.1.11.2 ko:K01142 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Exo_endo_phos k141_31218_2 42565.FP66_02105 2.45e-09 56.2 COG0461@1|root,COG0461@2|Bacteria,1MW6F@1224|Proteobacteria,1RQYG@1236|Gammaproteobacteria,1XHYH@135619|Oceanospirillales 135619|Oceanospirillales F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) pyrE - 2.4.2.10 ko:K00762 ko00240,ko01100,map00240,map01100 M00051 R01870 RC00611 ko00000,ko00001,ko00002,ko01000 - - - Pribosyltran k141_27550_1 218284.CCDN010000001_gene222 1.05e-110 326.0 COG0616@1|root,COG0616@2|Bacteria,1TRQW@1239|Firmicutes,4HB4R@91061|Bacilli,1ZBTV@1386|Bacillus 91061|Bacilli OU signal peptide peptidase SppA sppA - - ko:K04773 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S49 k141_27550_2 218284.CCDN010000001_gene223 1.11e-81 246.0 COG1714@1|root,COG1714@2|Bacteria,1V6QH@1239|Firmicutes,4HJKR@91061|Bacilli,1ZRW8@1386|Bacillus 91061|Bacilli S membrane protein domain - - - - - - - - - - - - RDD k141_35888_1 218284.CCDN010000001_gene164 3.44e-187 535.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,1ZBIW@1386|Bacillus 91061|Bacilli V COG1132 ABC-type multidrug transport system, ATPase and permease components yknV GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702 - ko:K02021,ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21 - - ABC_membrane,ABC_tran k141_32274_1 218284.CCDN010000001_gene1365 7.26e-113 335.0 COG2223@1|root,COG2223@2|Bacteria,1TPTN@1239|Firmicutes,4HA7C@91061|Bacilli,1ZB21@1386|Bacillus 91061|Bacilli P COG0477 Permeases of the major facilitator superfamily fsr GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K08223 - - - - ko00000,ko02000 2.A.1.35 - - MFS_1 k141_15747_1 1453501.JELR01000001_gene2594 3.78e-309 851.0 COG3634@1|root,COG3634@2|Bacteria,1MUKD@1224|Proteobacteria,1RNC7@1236|Gammaproteobacteria,465DW@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG3634 Alkyl hydroperoxide reductase, large subunit ahpF GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008785,GO:0009321,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071949,GO:0097159,GO:1901265,GO:1901363,GO:1902494,GO:1990204 - ko:K03387 - - - - ko00000,ko01000 - - - Pyr_redox_2,Thioredoxin_3 k141_15747_2 425104.Ssed_2456 1.39e-34 121.0 COG3791@1|root,COG3791@2|Bacteria,1N031@1224|Proteobacteria,1S990@1236|Gammaproteobacteria,2QC1R@267890|Shewanellaceae 1236|Gammaproteobacteria S Glutathione-dependent formaldehyde-activating enzyme - - - - - - - - - - - - GFA k141_20411_1 1211814.CAPG01000034_gene1659 2.65e-102 328.0 COG0464@1|root,COG0464@2|Bacteria,1TPQZ@1239|Firmicutes,4HCQK@91061|Bacilli,1ZCWD@1386|Bacillus 91061|Bacilli O stage V sporulation protein K - - - ko:K06413 - - - - ko00000 - - - AAA k141_16959_2 1384054.N790_04560 1.24e-07 54.3 COG4967@1|root,COG4967@2|Bacteria,1QHAU@1224|Proteobacteria,1SX42@1236|Gammaproteobacteria,1X7QT@135614|Xanthomonadales 135614|Xanthomonadales NU type IV pilus modification protein PilV - - - - - - - - - - - - N_methyl k141_26570_1 218284.CCDN010000001_gene1677 4.74e-86 268.0 COG0477@1|root,COG2814@2|Bacteria,1TPRN@1239|Firmicutes,4H9VV@91061|Bacilli,1ZAXQ@1386|Bacillus 91061|Bacilli EGP the major facilitator superfamily emrB_2 - - - - - - - - - - - MFS_1 k141_28864_1 861299.J421_3347 1.69e-49 160.0 COG2185@1|root,COG2185@2|Bacteria,1ZTNN@142182|Gemmatimonadetes 142182|Gemmatimonadetes I B12 binding domain - - 5.4.99.2 ko:K01849 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00375,M00376,M00741 R00833 RC00395 ko00000,ko00001,ko00002,ko01000 - - - B12-binding k141_28864_2 1463920.JOGB01000022_gene4426 3.3e-07 53.1 COG1884@1|root,COG1884@2|Bacteria,2GM65@201174|Actinobacteria 201174|Actinobacteria I Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly icmA - 5.4.99.2 ko:K01848 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00375,M00376,M00741 R00833 RC00395 ko00000,ko00001,ko00002,ko01000 - - - MM_CoA_mutase k141_31219_2 1123518.ARWI01000001_gene72 3.42e-14 75.1 COG0428@1|root,COG2905@1|root,COG0428@2|Bacteria,COG2905@2|Bacteria,1QE6Q@1224|Proteobacteria,1S080@1236|Gammaproteobacteria 1236|Gammaproteobacteria P signal-transduction protein containing cAMP-binding and CBS domains - - - ko:K07238 - - - - ko00000,ko02000 2.A.5.5 - - cNMP_binding k141_34747_1 342610.Patl_2222 8.58e-215 608.0 COG1816@1|root,COG1816@2|Bacteria,1R6Q8@1224|Proteobacteria,1S01A@1236|Gammaproteobacteria 1236|Gammaproteobacteria F adenosine deaminase - - 3.5.4.4 ko:K19572 ko00230,ko01100,map00230,map01100 - R01560 RC00477 ko00000,ko00001,ko01000 - - - A_deaminase k141_34747_2 745411.B3C1_01365 9.7e-07 49.3 COG1629@1|root,COG1629@2|Bacteria,1QTVF@1224|Proteobacteria,1T40W@1236|Gammaproteobacteria 1236|Gammaproteobacteria P TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_12240_2 1336245.JAGO01000010_gene606 1.51e-121 348.0 COG0717@1|root,COG0717@2|Bacteria,1MV2J@1224|Proteobacteria,1RMCD@1236|Gammaproteobacteria,1XI80@135619|Oceanospirillales 135619|Oceanospirillales F Belongs to the dCTP deaminase family dcd - 3.5.4.13 ko:K01494 ko00240,ko01100,map00240,map01100 M00053 R00568,R02325 RC00074 ko00000,ko00001,ko00002,ko01000 - - - dUTPase k141_1420_1 986075.CathTA2_1218 3.69e-38 137.0 COG1619@1|root,COG1619@2|Bacteria,1TRBB@1239|Firmicutes,4HAWT@91061|Bacilli 91061|Bacilli V proteins, homologs of microcin C7 resistance protein MccF ykfA - 3.4.17.13 ko:K01297 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_S66 k141_1420_2 1294265.JCM21738_1431 1.99e-50 171.0 COG4948@1|root,COG4948@2|Bacteria,1TQMS@1239|Firmicutes,4HCY5@91061|Bacilli,1ZC5Y@1386|Bacillus 91061|Bacilli M Belongs to the mandelate racemase muconate lactonizing enzyme family ykfB - 5.1.1.20 ko:K19802 - - R10938 RC03309 ko00000,ko01000 - - - MR_MLE_C,MR_MLE_N k141_27551_1 253839.SSNG_06492 2.24e-07 53.1 COG1359@1|root,COG1359@2|Bacteria,2GR78@201174|Actinobacteria 201174|Actinobacteria S Antibiotic biosynthesis monooxygenase - - - - - - - - - - - - ABM k141_19280_1 218284.CCDN010000002_gene2833 2.44e-112 334.0 COG0370@1|root,COG0370@2|Bacteria,1TP7E@1239|Firmicutes,4HDFJ@91061|Bacilli,1ZQG5@1386|Bacillus 91061|Bacilli P Ferrous iron transport protein B C terminus - - - ko:K04759 - - - - ko00000,ko02000 9.A.8.1 - - FeoB_C,FeoB_N,Gate k141_32276_1 218284.CCDN010000004_gene3078 2.42e-85 272.0 COG3973@1|root,COG3973@2|Bacteria,1TP39@1239|Firmicutes,4H9Y5@91061|Bacilli,1ZAWP@1386|Bacillus 91061|Bacilli L DNA helicase helD_2 - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_19,UvrD-helicase,UvrD_C,UvrD_C_2 k141_16961_1 1042377.AFPJ01000037_gene2850 1.01e-80 263.0 COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,464QT@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0642 Signal transduction histidine kinase barA GO:0000155,GO:0000160,GO:0000302,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009636,GO:0009927,GO:0009987,GO:0010033,GO:0010035,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0035556,GO:0036211,GO:0042221,GO:0042493,GO:0042542,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046677,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0070887,GO:0071310,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901700 2.7.13.3 ko:K07678 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 M00475 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - DUF2222,HAMP,HATPase_c,HisKA,Hpt,Response_reg k141_5006_1 218284.CCDN010000001_gene534 2.62e-81 241.0 2C26N@1|root,32K4G@2|Bacteria,1VAMA@1239|Firmicutes,4HJZD@91061|Bacilli,1ZHTT@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_5006_2 218284.CCDN010000001_gene535 5.96e-99 288.0 COG1327@1|root,COG1327@2|Bacteria,1V3JA@1239|Firmicutes,4HGXA@91061|Bacilli,1ZFS0@1386|Bacillus 91061|Bacilli K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes nrdR - - ko:K07738 - - - - ko00000,ko03000 - - - ATP-cone k141_35890_1 218284.CCDN010000001_gene1308 6.13e-125 370.0 COG0697@1|root,COG0697@2|Bacteria,1TP7K@1239|Firmicutes,4HAH1@91061|Bacilli,1ZBEF@1386|Bacillus 91061|Bacilli EG Spore germination protein gerAA_1 - - ko:K06295 - - - - ko00000 - - - GerA k141_24014_1 1042377.AFPJ01000055_gene959 0.0 2198.0 COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,1RPAG@1236|Gammaproteobacteria,465SE@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Non-ribosomal peptide synthetase - - - - - - - - - - - - AMP-binding,AMP-binding_C,Acyl_transf_1,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_12,PP-binding,Thioesterase,ketoacyl-synt k141_24014_2 1042377.AFPJ01000055_gene958 2.46e-136 392.0 COG1352@1|root,COG1352@2|Bacteria,1MVP3@1224|Proteobacteria,1S1XK@1236|Gammaproteobacteria 1236|Gammaproteobacteria NT Chemotaxis protein CheR wspC - 2.1.1.80 ko:K00575,ko:K13486 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko01000,ko02035 - - - CheR,CheR_N,TPR_8 k141_24014_3 1042377.AFPJ01000036_gene1167 1.01e-62 207.0 COG2979@1|root,COG2979@2|Bacteria,1R95E@1224|Proteobacteria,1S2WZ@1236|Gammaproteobacteria,467M2@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF533) yebE - - - - - - - - - - - DUF533 k141_24014_4 1042377.AFPJ01000036_gene1166 1.04e-175 496.0 COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,1RMRD@1236|Gammaproteobacteria,464C7@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0530 Ca2 Na antiporter - - - ko:K07301 - - - - ko00000,ko02000 2.A.19.5 - - Na_Ca_ex k141_24014_5 765913.ThidrDRAFT_0731 1.59e-36 126.0 COG0789@1|root,COG0789@2|Bacteria,1N9MT@1224|Proteobacteria,1SE7J@1236|Gammaproteobacteria,1WZDM@135613|Chromatiales 135613|Chromatiales K MerR HTH family regulatory protein - - - ko:K18997 - - - - ko00000,ko03036 - - - MerR_2 k141_24014_6 1279017.AQYJ01000027_gene1705 3.81e-182 512.0 COG0484@1|root,COG0484@2|Bacteria,1MUZ4@1224|Proteobacteria,1RP09@1236|Gammaproteobacteria,4668N@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG2214 DnaJ-class molecular chaperone cbpA GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0097159,GO:1901363 - ko:K05516 - - - - ko00000,ko03036,ko03110 - - - DnaJ,DnaJ_C k141_24014_8 1453501.JELR01000002_gene1027 6.16e-215 615.0 COG2268@1|root,COG2268@2|Bacteria,1P50K@1224|Proteobacteria,1RRHJ@1236|Gammaproteobacteria,465T9@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria yqiK GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - ko:K07192 ko04910,map04910 - - - ko00000,ko00001,ko03036,ko04131,ko04147 - - - Band_7,Flot k141_24014_9 1453501.JELR01000002_gene1028 1.12e-111 325.0 COG1585@1|root,COG1585@2|Bacteria,1RG29@1224|Proteobacteria,1S7HI@1236|Gammaproteobacteria,467KK@72275|Alteromonadaceae 1236|Gammaproteobacteria OU Protein of unknown function (DUF1449) - - - - - - - - - - - - DUF1449 k141_24014_10 1453501.JELR01000002_gene1029 1.69e-119 345.0 COG1842@1|root,COG1842@2|Bacteria,1NB0D@1224|Proteobacteria,1RTFI@1236|Gammaproteobacteria,467CV@72275|Alteromonadaceae 1236|Gammaproteobacteria KT PspA/IM30 family - - - - - - - - - - - - PspA_IM30 k141_24014_11 1453501.JELR01000002_gene1030 8.86e-58 185.0 2FEBB@1|root,346B2@2|Bacteria,1P137@1224|Proteobacteria,1SRAD@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_26573_1 218284.CCDN010000001_gene1109 5.74e-73 228.0 COG0142@1|root,COG0142@2|Bacteria,1V1TG@1239|Firmicutes,4HFY5@91061|Bacilli,1ZQJT@1386|Bacillus 91061|Bacilli H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 hepS GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.30 ko:K00805 ko00900,ko01110,map00900,map01110 - R09247 RC00279 ko00000,ko00001,ko01000,ko01006 - - - HEPPP_synt_1 k141_8627_1 646529.Desaci_1530 3.35e-50 179.0 COG2247@1|root,COG2247@2|Bacteria,1VDZC@1239|Firmicutes 1239|Firmicutes M Cell wall binding repeat 2 - - - ko:K20276 ko02024,map02024 - - - ko00000,ko00001 - - - Amidase_2,Big_2,CW_binding_2,DUF4430 k141_18192_1 768671.ThimaDRAFT_4573 4.82e-40 153.0 COG0845@1|root,COG0845@2|Bacteria,1PQHB@1224|Proteobacteria,1T9ZT@1236|Gammaproteobacteria,1WYMB@135613|Chromatiales 135613|Chromatiales M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - - - - - - - - - - HlyD_3,HlyD_D23 k141_18192_2 1122194.AUHU01000003_gene2119 4.65e-48 171.0 COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,1RNIF@1236|Gammaproteobacteria,465NJ@72275|Alteromonadaceae 1236|Gammaproteobacteria P Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family cecA_2 - - ko:K07239 - - - - ko00000 2.A.6.1 - - ACR_tran k141_15764_1 1294265.JCM21738_102 1.97e-35 120.0 2E5GX@1|root,3308G@2|Bacteria,1VGKE@1239|Firmicutes,4HPSE@91061|Bacilli,1ZIU7@1386|Bacillus 91061|Bacilli - - ypzH - - - - - - - - - - - - k141_15764_2 1294265.JCM21738_103 3.69e-213 595.0 COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,4HAJ6@91061|Bacilli,1ZAUP@1386|Bacillus 91061|Bacilli S GTPase that plays an essential role in the late steps of ribosome biogenesis der - - ko:K03977 - - - - ko00000,ko03009 - - - KH_dom-like,MMR_HSR1 k141_6358_1 218284.CCDN010000001_gene203 1.53e-45 154.0 COG0390@1|root,COG0390@2|Bacteria,1UY1N@1239|Firmicutes,4HDM4@91061|Bacilli,1ZB6C@1386|Bacillus 91061|Bacilli S transport system, permease component yjkA GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0009987,GO:0015075,GO:0016020,GO:0016021,GO:0019725,GO:0022857,GO:0030003,GO:0031224,GO:0031226,GO:0034220,GO:0042592,GO:0044425,GO:0044459,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071944,GO:0098771 - ko:K02069 - M00211 - - ko00000,ko00002,ko02000 9.B.25.1 - - UPF0014 k141_6358_2 218284.CCDN010000001_gene204 1.06e-91 273.0 COG1136@1|root,COG1136@2|Bacteria,1V3HH@1239|Firmicutes,4HHE3@91061|Bacilli,1ZE0V@1386|Bacillus 91061|Bacilli V ABC transporter - - - ko:K02068 - M00211 - - ko00000,ko00002,ko02000 - - - ABC_tran k141_21711_1 313628.LNTAR_25170 8.62e-25 101.0 COG2755@1|root,COG2755@2|Bacteria 2|Bacteria E lipolytic protein G-D-S-L family - - 3.1.1.5 ko:K10804 ko01040,map01040 - - - ko00000,ko00001,ko01000,ko01004 - - - SASA k141_24043_1 1294265.JCM21738_1422 4.38e-120 347.0 COG2362@1|root,COG2362@2|Bacteria,1TSUZ@1239|Firmicutes,4HC5R@91061|Bacilli,1ZC41@1386|Bacillus 91061|Bacilli E D-aminopeptidase dppA - - ko:K16203 - - - - ko00000,ko01000,ko01002 3.A.1.5.2 - iYO844.BSU12920 Peptidase_M55 k141_12269_1 218284.CCDN010000007_gene3973 7.21e-75 234.0 COG1158@1|root,COG1158@2|Bacteria,1TPHZ@1239|Firmicutes,4H9XB@91061|Bacilli,1ZBN9@1386|Bacillus 91061|Bacilli K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template rho - - ko:K03628 ko03018,map03018 - - - ko00000,ko00001,ko03019,ko03021 - - - ATP-synt_ab,Rho_N,Rho_RNA_bind k141_32304_1 203122.Sde_1206 2.67e-63 195.0 COG0335@1|root,COG0335@2|Bacteria,1RH3A@1224|Proteobacteria,1S5XX@1236|Gammaproteobacteria,466X0@72275|Alteromonadaceae 1236|Gammaproteobacteria J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site rplS GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02884 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L19 k141_32304_2 1042377.AFPJ01000037_gene2888 3.57e-09 56.6 COG0336@1|root,COG0336@2|Bacteria,1MUN1@1224|Proteobacteria,1RMWC@1236|Gammaproteobacteria,464K1@72275|Alteromonadaceae 1236|Gammaproteobacteria J Belongs to the RNA methyltransferase TrmD family trmD GO:0000287,GO:0001510,GO:0002939,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050518,GO:0052906,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 ko:K00554 - - R00597 RC00003,RC00334 ko00000,ko01000,ko03016 - - - tRNA_m1G_MT k141_16004_2 314256.OG2516_05123 1.57e-20 85.9 29EMG@1|root,301JE@2|Bacteria,1RD6J@1224|Proteobacteria,2U79C@28211|Alphaproteobacteria,2PE51@252301|Oceanicola 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_17186_1 1294265.JCM21738_3838 2.91e-111 323.0 COG1296@1|root,COG1296@2|Bacteria,1TSXD@1239|Firmicutes,4HJCQ@91061|Bacilli,1ZDNM@1386|Bacillus 91061|Bacilli E branched-chain amino acid - - - - - - - - - - - - AzlC k141_21959_1 187272.Mlg_0478 4.45e-73 234.0 COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,1RNJV@1236|Gammaproteobacteria,1WWJA@135613|Chromatiales 135613|Chromatiales U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently secY - - ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5 - - SecY k141_10213_1 1211817.CCAT010000044_gene3350 9.41e-18 85.9 COG1664@1|root,COG1664@2|Bacteria,1V6E6@1239|Firmicutes,24E2Y@186801|Clostridia,36GS1@31979|Clostridiaceae 186801|Clostridia M COG1664 Integral membrane protein CcmA involved in cell shape determination - - - - - - - - - - - - Bactofilin k141_4176_2 1042377.AFPJ01000015_gene1617 6.59e-100 296.0 COG2761@1|root,COG2761@2|Bacteria,1NXUB@1224|Proteobacteria,1S2Z2@1236|Gammaproteobacteria,466WX@72275|Alteromonadaceae 1236|Gammaproteobacteria Q dithiol-disulfide isomerase involved in polyketide biosynthesis - - - - - - - - - - - - DSBA k141_4176_3 1042377.AFPJ01000015_gene1618 6.76e-100 295.0 28IPG@1|root,2Z8PF@2|Bacteria,1P8KM@1224|Proteobacteria,1RY74@1236|Gammaproteobacteria,466DF@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_4176_4 225937.HP15_1683 1e-47 156.0 COG3791@1|root,COG3791@2|Bacteria,1RCYS@1224|Proteobacteria,1S3X0@1236|Gammaproteobacteria,46C99@72275|Alteromonadaceae 1236|Gammaproteobacteria S Glutathione-dependent formaldehyde-activating enzyme - - - - - - - - - - - - GFA k141_4176_5 1453501.JELR01000002_gene481 4.28e-159 451.0 COG0627@1|root,COG0627@2|Bacteria,1MUID@1224|Proteobacteria,1RMR3@1236|Gammaproteobacteria,46528@72275|Alteromonadaceae 1236|Gammaproteobacteria S Serine hydrolase involved in the detoxification of formaldehyde yeiG GO:0003674,GO:0003824,GO:0004416,GO:0005488,GO:0005515,GO:0006081,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010033,GO:0016043,GO:0016787,GO:0016788,GO:0016790,GO:0016999,GO:0017001,GO:0017144,GO:0018738,GO:0022607,GO:0042221,GO:0042802,GO:0043933,GO:0044085,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046185,GO:0046292,GO:0046294,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051716,GO:0065003,GO:0070887,GO:0071704,GO:0071840,GO:0097237,GO:0098754,GO:0110095,GO:0110096,GO:1901575,GO:1901700,GO:1901701,GO:1990748 3.1.2.12 ko:K01070 ko00680,ko01120,ko01200,map00680,map01120,map01200 - R00527 RC00167,RC00320 ko00000,ko00001,ko01000 - CE1 iAF1260.b0355,iBWG_1329.BWG_0244,iE2348C_1286.E2348C_2300,iECDH10B_1368.ECDH10B_0310,iECDH1ME8569_1439.ECDH1ME8569_0342,iEcDH1_1363.EcDH1_3251,iG2583_1286.G2583_0468,iJO1366.b0355,iY75_1357.Y75_RS01830 Esterase k141_4176_7 1279017.AQYJ01000028_gene2428 3.29e-143 415.0 COG2207@1|root,COG2207@2|Bacteria,1MX23@1224|Proteobacteria,1RRXM@1236|Gammaproteobacteria 1236|Gammaproteobacteria K AraC family transcriptional regulator - - - - - - - - - - - - Arabinose_bd,HTH_18 k141_29057_1 218284.CCDN010000001_gene1385 4.51e-109 325.0 COG0014@1|root,COG0014@2|Bacteria,1TQ9V@1239|Firmicutes,4HB7B@91061|Bacilli,1ZC00@1386|Bacillus 91061|Bacilli E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate proA - 1.2.1.41 ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 M00015 R03313 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_16005_1 358823.DF19_10280 3.59e-09 62.8 COG2244@1|root,COG2244@2|Bacteria,2GPBA@201174|Actinobacteria 201174|Actinobacteria S Polysaccharide biosynthesis C-terminal domain - - - - - - - - - - - - Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C k141_16005_2 1307759.JOMJ01000004_gene2482 1.85e-05 47.4 COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,42MRN@68525|delta/epsilon subdivisions,2WJCH@28221|Deltaproteobacteria,2M8K3@213115|Desulfovibrionales 28221|Deltaproteobacteria M PFAM NAD-dependent epimerase dehydratase - - 5.1.3.2,5.1.3.7 ko:K01784,ko:K02473 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R00418,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase,GDP_Man_Dehyd k141_6553_1 1279017.AQYJ01000028_gene2537 1.57e-198 578.0 COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,1RMWN@1236|Gammaproteobacteria,465G2@72275|Alteromonadaceae 1236|Gammaproteobacteria C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family nasA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K00372 ko00910,ko01120,map00910,map01120 M00531 R00798,R01106 RC02812 ko00000,ko00001,ko00002,ko01000 - - - Fer2_BFD,Molybdop_Fe4S4,Molybdopterin,Molydop_binding k141_6553_2 1453501.JELR01000002_gene389 2.55e-51 165.0 COG2146@1|root,COG2146@2|Bacteria,1MZBY@1224|Proteobacteria,1S9F1@1236|Gammaproteobacteria,467QP@72275|Alteromonadaceae 1236|Gammaproteobacteria P Nitrite reductase nirD - 1.7.1.15 ko:K00363 ko00910,ko01120,map00910,map01120 M00530 R00787 RC00176 ko00000,ko00001,ko00002,ko01000 - - - Rieske_2 k141_19637_1 218284.CCDN010000001_gene1207 2.54e-127 366.0 COG1404@1|root,COG1404@2|Bacteria,1V3SC@1239|Firmicutes,4HGZF@91061|Bacilli,1ZGVY@1386|Bacillus 91061|Bacilli O Domain of unknown function (DUF4397) - - - - - - - - - - - - DUF4397 k141_35080_1 218284.CCDN010000001_gene495 1.83e-159 456.0 COG0477@1|root,COG2814@2|Bacteria,1TQXU@1239|Firmicutes,4HAYB@91061|Bacilli,1ZQ77@1386|Bacillus 91061|Bacilli EGP -transporter ytbD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K19577 - - - - ko00000,ko02000 2.A.1.2.65 - - MFS_1,Sugar_tr k141_37349_1 1279017.AQYJ01000026_gene351 4.32e-14 70.5 COG2171@1|root,COG2171@2|Bacteria,1MYKK@1224|Proteobacteria,1RM8X@1236|Gammaproteobacteria,46580@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA dapD GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008666,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.117 ko:K00674 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R04365 RC00004,RC01136 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_1530 Hexapep_2,THDPS_M,THDPS_N k141_37349_2 1279017.AQYJ01000026_gene350 8.58e-57 178.0 COG1393@1|root,COG1393@2|Bacteria,1MZ6S@1224|Proteobacteria,1S8TR@1236|Gammaproteobacteria,467VK@72275|Alteromonadaceae 1236|Gammaproteobacteria P Belongs to the ArsC family yffB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.20.4.1 ko:K00537 - - - - ko00000,ko01000 - - - ArsC k141_5426_1 935567.JAES01000002_gene772 8.04e-69 224.0 COG1070@1|root,COG1070@2|Bacteria,1MW4A@1224|Proteobacteria,1RR7X@1236|Gammaproteobacteria,1X4TN@135614|Xanthomonadales 135614|Xanthomonadales G Xylulose kinase xylB - 2.7.1.17 ko:K00854 ko00040,ko01100,map00040,map01100 M00014 R01639 RC00002,RC00538 ko00000,ko00001,ko00002,ko01000 - - - FGGY_C,FGGY_N k141_8967_1 1123237.Salmuc_05618 1.59e-58 182.0 2CJPJ@1|root,32SAG@2|Bacteria,1N26R@1224|Proteobacteria,2UCCP@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_8967_2 766499.C357_20470 1.41e-27 107.0 COG1702@1|root,COG1702@2|Bacteria,1MVDV@1224|Proteobacteria,2TRV3@28211|Alphaproteobacteria 28211|Alphaproteobacteria T Phosphate starvation-inducible protein PhoH phoH - - ko:K06217 - - - - ko00000 - - - PhoH k141_12639_2 218284.CCDN010000004_gene3137 1.67e-91 273.0 COG0702@1|root,COG0702@2|Bacteria,1TS7J@1239|Firmicutes,4HFT3@91061|Bacilli,1ZGA3@1386|Bacillus 91061|Bacilli GM NAD(P)H-binding yheG - - - - - - - - - - - NAD_binding_10 k141_12639_3 218284.CCDN010000004_gene3138 1.69e-151 429.0 COG0834@1|root,COG0834@2|Bacteria,1TR13@1239|Firmicutes,4HBRP@91061|Bacilli,1ZCH3@1386|Bacillus 91061|Bacilli ET Belongs to the bacterial solute-binding protein 3 family tcyA - - ko:K02424 ko02010,map02010 M00234 - - ko00000,ko00001,ko00002,ko02000,ko02035 3.A.1.3.10,3.A.1.3.14 - - SBP_bac_3 k141_16006_1 1307436.PBF_00260 1.84e-139 399.0 COG0584@1|root,COG0584@2|Bacteria,1UGF1@1239|Firmicutes,4H9QE@91061|Bacilli,1ZPVG@1386|Bacillus 91061|Bacilli C Glycerophosphoryl diester phosphodiesterase family glpQ - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - DUF1080,GDPD k141_35081_1 1042377.AFPJ01000030_gene447 1.58e-95 303.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MV8W@1224|Proteobacteria,1RMQA@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Outer membrane receptor proteins mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec k141_37350_1 796606.BMMGA3_10635 1.43e-79 248.0 COG0438@1|root,COG0438@2|Bacteria,1TPS8@1239|Firmicutes,4HA43@91061|Bacilli,1ZASJ@1386|Bacillus 91061|Bacilli M N-acetyl-alpha-D-glucosaminyl L-malate synthase bshA - - ko:K00754 - - - - ko00000,ko01000 - GT4 - Glyco_transf_4,Glycos_transf_1 k141_26967_2 1231057.AMGD01000108_gene344 5.23e-33 126.0 COG2755@1|root,COG2755@2|Bacteria,1UYZ1@1239|Firmicutes,4HUMR@91061|Bacilli 91061|Bacilli E GDSL-like Lipase/Acylhydrolase family - - - - - - - - - - - - Lipase_GDSL_2 k141_17187_1 218284.CCDN010000001_gene749 1.74e-177 520.0 COG1480@1|root,COG1480@2|Bacteria,1TR1A@1239|Firmicutes,4HAEZ@91061|Bacilli,1ZANS@1386|Bacillus 91061|Bacilli S membrane-associated HD superfamily hydrolase yqfF - - ko:K07037 - - - - ko00000 - - - 7TM-7TMR_HD,7TMR-HDED,HD k141_13827_2 223926.28806610 8.54e-196 545.0 COG1648@1|root,COG1648@2|Bacteria,1RB3H@1224|Proteobacteria,1SPHW@1236|Gammaproteobacteria,1XT8S@135623|Vibrionales 135623|Vibrionales H COG1648 Siroheme synthase (precorrin-2 oxidase ferrochelatase domain) cysG - 1.3.1.76,4.99.1.4 ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02864,R03947 RC01012,RC01034 ko00000,ko00001,ko00002,ko01000 - - - CysG_dimeriser,NAD_binding_7,Sirohm_synth_M k141_35125_1 118161.KB235922_gene4606 9.08e-70 227.0 COG0405@1|root,COG0405@2|Bacteria,1G0GU@1117|Cyanobacteria,3VI9R@52604|Pleurocapsales 1117|Cyanobacteria E Gamma-glutamyltranspeptidase - - 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept k141_21985_2 1196031.ALEG01000020_gene3055 2.88e-31 122.0 COG2866@1|root,COG2866@2|Bacteria,1TP3K@1239|Firmicutes,4HAHN@91061|Bacilli,1ZD1J@1386|Bacillus 91061|Bacilli E Gamma-D-glutamyl-L-diamino acid endopeptidase yqgT GO:0003674,GO:0003824,GO:0004180,GO:0004181,GO:0005575,GO:0005576,GO:0005615,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0044421,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.19.11 ko:K01308 - - - - ko00000,ko01000,ko01002 - - - LysM,Peptidase_M14 k141_18528_1 1033734.CAET01000010_gene1824 1.56e-75 228.0 28T9W@1|root,2ZFIH@2|Bacteria,1V1JV@1239|Firmicutes,4HFXV@91061|Bacilli,1ZGK3@1386|Bacillus 91061|Bacilli K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization hutP GO:0006082,GO:0006355,GO:0006520,GO:0006547,GO:0006548,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016054,GO:0019219,GO:0019222,GO:0019439,GO:0019752,GO:0031323,GO:0031326,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0052803,GO:0052805,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1903506,GO:2000112,GO:2001141 - ko:K09683 - - - - ko00000,ko03000 - - - HutP k141_19655_1 218284.CCDN010000001_gene1074 4.23e-97 291.0 COG0438@1|root,COG0438@2|Bacteria,1TPTA@1239|Firmicutes,4HA41@91061|Bacilli,1ZD6V@1386|Bacillus 91061|Bacilli M Glycosyl Transferase - - 2.4.1.337 ko:K19002 ko00561,ko01100,map00561,map01100 - R10850 RC00005,RC00059 ko00000,ko00001,ko01000,ko01003 - GT4 - Glyco_transf_4,Glycos_transf_1 k141_2907_1 1294265.JCM21738_3216 1.02e-167 470.0 COG0706@1|root,COG0706@2|Bacteria,1TQ0J@1239|Firmicutes,4HB3J@91061|Bacilli,1ZBYD@1386|Bacillus 91061|Bacilli U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins yidC GO:0005575,GO:0008150,GO:0009653,GO:0009987,GO:0016020,GO:0030154,GO:0030435,GO:0032502,GO:0043934,GO:0048646,GO:0048856,GO:0048869 - ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 - - 60KD_IMP k141_27763_1 1042377.AFPJ01000004_gene415 1.68e-61 198.0 COG1521@1|root,COG1521@2|Bacteria,1MUYA@1224|Proteobacteria,1S99V@1236|Gammaproteobacteria,467TT@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis coaX - 2.7.1.33 ko:K03525 ko00770,ko01100,map00770,map01100 M00120 R02971,R03018,R04391 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Pan_kinase k141_14787_1 171693.BN988_02229 1.62e-37 134.0 COG1063@1|root,COG1063@2|Bacteria,1VRPE@1239|Firmicutes,4HU28@91061|Bacilli 91061|Bacilli E alcohol dehydrogenase - - 1.1.1.1 ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N k141_14787_3 574375.BAGA_25890 1.29e-98 295.0 COG0327@1|root,COG0327@2|Bacteria,1V149@1239|Firmicutes,4I7AR@91061|Bacilli,1ZFDI@1386|Bacillus 91061|Bacilli S NIF3 (NGG1p interacting factor 3) - - - - - - - - - - - - NIF3 k141_32545_1 1453501.JELR01000002_gene611 3.13e-92 276.0 COG0494@1|root,COG0494@2|Bacteria,1RDMW@1224|Proteobacteria,1RPZV@1236|Gammaproteobacteria,4670F@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes nudF GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019144,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0047631,GO:0050896 3.6.1.13 ko:K01515 ko00230,map00230 - R01054 RC00002 ko00000,ko00001,ko01000 - - iECP_1309.ECP_3126 NUDIX k141_32545_2 1279017.AQYJ01000028_gene2214 2.65e-58 187.0 COG3151@1|root,COG3151@2|Bacteria,1RA4E@1224|Proteobacteria,1S55I@1236|Gammaproteobacteria,468KM@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria yqiB - - ko:K09920 - - - - ko00000 - - - DUF1249 k141_32545_3 1279017.AQYJ01000028_gene2215 3.93e-103 306.0 COG1409@1|root,COG1409@2|Bacteria,1MWKX@1224|Proteobacteria,1RPA7@1236|Gammaproteobacteria,466SM@72275|Alteromonadaceae 1236|Gammaproteobacteria S Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes cpdA GO:0003674,GO:0003824,GO:0004112,GO:0004114,GO:0004115,GO:0005488,GO:0005506,GO:0008081,GO:0008150,GO:0008198,GO:0009987,GO:0016043,GO:0016787,GO:0016788,GO:0042545,GO:0042578,GO:0043167,GO:0043169,GO:0045229,GO:0046872,GO:0046914,GO:0071554,GO:0071555,GO:0071840 3.1.4.53 ko:K03651 ko00230,ko02025,map00230,map02025 - R00191 RC00296 ko00000,ko00001,ko01000 - - - Metallophos k141_25685_1 218284.CCDN010000002_gene2573 6.66e-235 659.0 COG0619@1|root,COG0619@2|Bacteria,1VBW7@1239|Firmicutes,4HB6S@91061|Bacilli,1ZS19@1386|Bacillus 91061|Bacilli P Spore gernimation protein GerA - - - - - - - - - - - - GerA k141_36138_1 1280001.BAOA01000128_gene1219 2.91e-31 114.0 COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,1RNU8@1236|Gammaproteobacteria,1XTRN@135623|Vibrionales 135623|Vibrionales J Belongs to the SUA5 family yciO - - - - - - - - - - - Sua5_yciO_yrdC k141_36138_2 223926.28806944 1.97e-37 134.0 COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,1SI25@1236|Gammaproteobacteria,1XVQT@135623|Vibrionales 135623|Vibrionales Q Haemolysin-type calcium-binding repeat (2 copies) - - - - - - - - - - - - HemolysinCabind k141_6578_1 218284.CCDN010000001_gene801 1.23e-70 229.0 COG0457@1|root,COG0705@1|root,COG0457@2|Bacteria,COG0705@2|Bacteria,1TQXT@1239|Firmicutes,4HCDF@91061|Bacilli,1ZBV7@1386|Bacillus 91061|Bacilli O membrane protein (homolog of Drosophila rhomboid) gluP - 3.4.21.105 ko:K19225 - - - - ko00000,ko01000,ko01002 - - - Rhomboid,TPR_2,TPR_8 k141_12666_2 1279017.AQYJ01000011_gene3050 1.67e-71 226.0 COG1521@1|root,COG1521@2|Bacteria,1MUYA@1224|Proteobacteria,1S99V@1236|Gammaproteobacteria,467TT@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis coaX - 2.7.1.33 ko:K03525 ko00770,ko01100,map00770,map01100 M00120 R02971,R03018,R04391 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Pan_kinase k141_12666_3 1042377.AFPJ01000004_gene416 4.73e-75 234.0 2E02Y@1|root,32VRV@2|Bacteria,1N1HZ@1224|Proteobacteria,1S93X@1236|Gammaproteobacteria,4688F@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - SPOR k141_33896_1 1116375.VEJY3_19821 4.5e-32 112.0 2BRIA@1|root,32KHA@2|Bacteria,1QKB1@1224|Proteobacteria,1TIEI@1236|Gammaproteobacteria,1XYZJ@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_33896_2 1348635.BBJY01000017_gene4140 5.44e-180 533.0 COG0834@1|root,COG2199@1|root,COG0834@2|Bacteria,COG2199@2|Bacteria,1RCU9@1224|Proteobacteria,1S2VP@1236|Gammaproteobacteria,1XZ8S@135623|Vibrionales 135623|Vibrionales T diguanylate cyclase - - - - - - - - - - - - GGDEF k141_33896_3 1348635.BBJY01000017_gene4140 6.45e-263 744.0 COG0834@1|root,COG2199@1|root,COG0834@2|Bacteria,COG2199@2|Bacteria,1RCU9@1224|Proteobacteria,1S2VP@1236|Gammaproteobacteria,1XZ8S@135623|Vibrionales 135623|Vibrionales T diguanylate cyclase - - - - - - - - - - - - GGDEF k141_4194_1 861299.J421_3391 1.43e-38 143.0 COG0124@1|root,COG0124@2|Bacteria,1ZSXX@142182|Gemmatimonadetes 142182|Gemmatimonadetes J Histidyl-tRNA synthetase hisS - 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_His k141_32546_1 218284.CCDN010000002_gene2507 1.44e-33 124.0 COG0657@1|root,COG0657@2|Bacteria,1TQHX@1239|Firmicutes,4HB91@91061|Bacilli,1ZB27@1386|Bacillus 91061|Bacilli I COG0657 Esterase lipase - - - ko:K01066 - - - - ko00000,ko01000 - - - Abhydrolase_3 k141_10249_2 1279017.AQYJ01000020_gene1352 2.45e-306 840.0 COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,1RPM2@1236|Gammaproteobacteria,4657V@72275|Alteromonadaceae 1236|Gammaproteobacteria L it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins dnaB GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k141_10249_3 1279017.AQYJ01000020_gene1353 1.13e-65 203.0 COG0359@1|root,COG0359@2|Bacteria,1RD0R@1224|Proteobacteria,1S3WS@1236|Gammaproteobacteria,466HW@72275|Alteromonadaceae 1236|Gammaproteobacteria J Binds to the 23S rRNA rplI GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02939 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L9_C,Ribosomal_L9_N k141_10249_4 1453501.JELR01000002_gene884 5.94e-94 283.0 2BFY8@1|root,329TX@2|Bacteria,1R582@1224|Proteobacteria,1S61M@1236|Gammaproteobacteria,467SZ@72275|Alteromonadaceae 1236|Gammaproteobacteria S Membrane - - - - - - - - - - - - - k141_2908_1 218284.CCDN010000002_gene2931 5.22e-123 359.0 COG1194@1|root,COG1194@2|Bacteria,1TPUT@1239|Firmicutes,4H9UM@91061|Bacilli,1ZD5Y@1386|Bacillus 91061|Bacilli L A G-specific mutY - - ko:K03575 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD,NUDIX_4 k141_17200_1 55601.VANGNB10_cII0408 4.17e-83 258.0 2AXPI@1|root,33SHH@2|Bacteria,1NQJ2@1224|Proteobacteria,1SKT5@1236|Gammaproteobacteria,1Y1FF@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_17200_2 1116375.VEJY3_08875 6.55e-114 328.0 COG0406@1|root,COG0406@2|Bacteria,1QJV2@1224|Proteobacteria,1THWM@1236|Gammaproteobacteria,1XXR2@135623|Vibrionales 135623|Vibrionales G Histidine phosphatase superfamily (branch 1) - - - - - - - - - - - - His_Phos_1 k141_17200_3 28229.ND2E_2151 2.17e-52 166.0 COG2329@1|root,COG2329@2|Bacteria,1N062@1224|Proteobacteria,1SABZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S enzyme involved in biosynthesis of extracellular polysaccharides yqjZ - - - - - - - - - - - ABM k141_17200_4 674977.VMC_32910 8.26e-110 317.0 COG3575@1|root,COG3575@2|Bacteria,1RK7B@1224|Proteobacteria,1T0ES@1236|Gammaproteobacteria,1Y2ZC@135623|Vibrionales 135623|Vibrionales S Nucleotidyltransferase - - - ko:K09962 - - - - ko00000 - - - NTP_transf_6 k141_17200_5 1116375.VEJY3_19201 6.23e-316 863.0 COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,1RMF3@1236|Gammaproteobacteria,1XWCQ@135623|Vibrionales 135623|Vibrionales P Sodium:sulfate symporter transmembrane region - - - ko:K03319 - - - - ko00000 2.A.47 - - Na_sulph_symp k141_11417_1 1042377.AFPJ01000028_gene2297 2.04e-72 237.0 COG1404@1|root,COG5640@1|root,COG1404@2|Bacteria,COG5640@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria,464PM@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG1404 Subtilisin-like serine proteases - GO:0005575,GO:0005576 - ko:K14645 ko02024,map02024 - - - ko00000,ko00001,ko01000,ko01002,ko03110 - - - PKD,PPC,P_proprotein,Peptidase_S8 k141_29078_1 1403313.AXBR01000006_gene96 1.28e-12 68.6 COG2755@1|root,COG2755@2|Bacteria,1UZYP@1239|Firmicutes,4HDQY@91061|Bacilli,1ZEFB@1386|Bacillus 91061|Bacilli E COG2755 Lysophospholipase L1 and related esterases - - - - - - - - - - - - Lipase_GDSL_2 k141_14788_1 1123508.JH636439_gene1076 7.16e-13 66.6 COG0454@1|root,COG0456@2|Bacteria,2J3JP@203682|Planctomycetes 203682|Planctomycetes K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1 k141_14788_2 1449063.JMLS01000046_gene3031 3.32e-63 199.0 COG0406@1|root,COG0406@2|Bacteria,1V54I@1239|Firmicutes,4HJ7S@91061|Bacilli,274HW@186822|Paenibacillaceae 91061|Bacilli G Phosphoglycerate mutase family - - 5.4.2.11 ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - His_Phos_1 k141_35130_1 1227360.C176_06932 4.65e-49 161.0 COG0454@1|root,COG0456@2|Bacteria,1VAU8@1239|Firmicutes,4IQ7V@91061|Bacilli,26G96@186818|Planococcaceae 91061|Bacilli K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - - - - - - - - - - Acetyltransf_1 k141_733_1 218284.CCDN010000011_gene4414 1.51e-276 764.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,4HA38@91061|Bacilli,1ZBKJ@1386|Bacillus 91061|Bacilli O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions groL GO:0001817,GO:0001819,GO:0001871,GO:0002791,GO:0002793,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009986,GO:0009987,GO:0016465,GO:0030246,GO:0030247,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044764,GO:0046812,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051082,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051704,GO:0061077,GO:0065007,GO:0070201,GO:0090087,GO:0098630,GO:0098743,GO:0101031,GO:1903530,GO:1903532,GO:1904951,GO:1990220,GO:2000482,GO:2000484,GO:2001065 - ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 - - - Cpn60_TCP1 k141_19658_1 218284.CCDN010000001_gene107 7.4e-106 317.0 COG3314@1|root,COG3314@2|Bacteria,1TR0V@1239|Firmicutes,4HB55@91061|Bacilli,1ZCCT@1386|Bacillus 91061|Bacilli S Sporulation integral membrane protein YlbJ ylbJ - - - - - - - - - - - Gate k141_10250_1 357808.RoseRS_3704 8.36e-46 166.0 COG0281@1|root,COG0281@2|Bacteria,2G65R@200795|Chloroflexi,376YS@32061|Chloroflexia 32061|Chloroflexia C Malic enzyme, NAD binding domain - - 1.1.1.38 ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 - R00214 RC00105 ko00000,ko00001,ko01000 - - - Malic_M,malic k141_11418_1 608538.HTH_1092 1.12e-29 117.0 COG1013@1|root,COG1013@2|Bacteria,2G42W@200783|Aquificae 200783|Aquificae C TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, beta subunit - - 1.2.7.11,1.2.7.3 ko:K00175 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - PFO_beta_C,TPP_enzyme_C k141_21986_1 218284.CCDN010000002_gene2945 5.12e-302 824.0 COG0001@1|root,COG0001@2|Bacteria,1TPNH@1239|Firmicutes,4HBDZ@91061|Bacilli,1ZB74@1386|Bacillus 91061|Bacilli H Glutamate-1-semialdehyde aminotransferase gsaB - 5.4.3.8 ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02272 RC00677 ko00000,ko00001,ko00002,ko01000,ko01007 - - iYO844.BSU08710 Aminotran_3 k141_12668_1 1385520.N802_15460 8.06e-94 277.0 2A0U6@1|root,30NYZ@2|Bacteria,2H2K1@201174|Actinobacteria,4FJAW@85021|Intrasporangiaceae 201174|Actinobacteria - - - - - - - - - - - - - - YecM k141_8984_1 1116375.VEJY3_00605 2.8e-90 272.0 COG3031@1|root,COG3031@2|Bacteria,1RD3I@1224|Proteobacteria,1RQKA@1236|Gammaproteobacteria,1XU1I@135623|Vibrionales 135623|Vibrionales U general secretion pathway protein epsC GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - ko:K02452 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSC k141_8984_2 1116375.VEJY3_00610 0.0 1203.0 COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,1RPJS@1236|Gammaproteobacteria,1XSIA@135623|Vibrionales 135623|Vibrionales NU General secretion pathway protein gspD - - ko:K02453 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - Secretin,Secretin_N k141_8984_3 1116375.VEJY3_00615 0.0 910.0 COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,1XTS6@135623|Vibrionales 135623|Vibrionales NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB epsE - - ko:K02454 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSE k141_8984_4 223926.28805117 7.65e-258 711.0 COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RQ86@1236|Gammaproteobacteria,1XTCY@135623|Vibrionales 135623|Vibrionales U general secretion pathway protein epsF GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0032940,GO:0033036,GO:0042886,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098776 - ko:K02455 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSF k141_8984_5 1219076.N646_2325 6.27e-99 287.0 COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,1S3VS@1236|Gammaproteobacteria,1XWYF@135623|Vibrionales 135623|Vibrionales U general secretion pathway protein epsG GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - ko:K02456 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - N_methyl,T2SSG k141_8984_6 674977.VMC_02760 2.84e-117 338.0 COG2165@1|root,COG2165@2|Bacteria,1N7HZ@1224|Proteobacteria,1SCWD@1236|Gammaproteobacteria,1XWQW@135623|Vibrionales 135623|Vibrionales NU COG2165 Type II secretory pathway, pseudopilin PulG epsH GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - ko:K02457 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - GspH,N_methyl k141_8984_7 1116375.VEJY3_00635 1.32e-71 217.0 COG2165@1|root,COG2165@2|Bacteria,1N737@1224|Proteobacteria,1SC8X@1236|Gammaproteobacteria,1XXW2@135623|Vibrionales 135623|Vibrionales NU COG2165 Type II secretory pathway, pseudopilin PulG epsI GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - ko:K02458 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - N_methyl,T2SSI k141_5456_2 1453501.JELR01000002_gene494 5.3e-265 734.0 COG0591@1|root,COG0591@2|Bacteria,1MUBI@1224|Proteobacteria,1RMXU@1236|Gammaproteobacteria,464J5@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - ko:K11928 - - - - ko00000,ko02000 2.A.21.2 - - SSF k141_5456_3 1123279.ATUS01000001_gene2650 1.06e-89 266.0 COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,1S24R@1236|Gammaproteobacteria,1J61J@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Belongs to the UPF0312 family yceI - - - - - - - - - - - YceI k141_734_1 479433.Caci_0846 1.68e-70 220.0 COG0377@1|root,COG0377@2|Bacteria,2GJP5@201174|Actinobacteria 201174|Actinobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoB2 - 1.6.5.3 ko:K00331 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q6 k141_16038_1 1279017.AQYJ01000024_gene1069 6.82e-254 717.0 COG0501@1|root,COG0501@2|Bacteria,1MVU4@1224|Proteobacteria,1RPJ5@1236|Gammaproteobacteria,46584@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG0501 Zn-dependent protease with chaperone function htpX - - ko:K03799 - M00743 - - ko00000,ko00002,ko01000,ko01002 - - - Peptidase_M48 k141_34073_1 1279017.AQYJ01000026_gene58 6.92e-257 795.0 COG1361@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4932@2|Bacteria,1R5G4@1224|Proteobacteria,1SEWA@1236|Gammaproteobacteria,469S7@72275|Alteromonadaceae 1236|Gammaproteobacteria M Domain of unknown function DUF11 - - - - - - - - - - - - DUF11,SdrD_B k141_19838_1 685778.AORL01000022_gene1463 5.83e-56 191.0 COG1232@1|root,COG1232@2|Bacteria,1MX35@1224|Proteobacteria,2TU7I@28211|Alphaproteobacteria,2K14D@204457|Sphingomonadales 204457|Sphingomonadales H Thi4 family - - - - - - - - - - - - Amino_oxidase,NAD_binding_8 k141_22192_1 218284.CCDN010000001_gene1242 6.5e-29 110.0 COG2340@1|root,COG2340@2|Bacteria,1V6GZ@1239|Firmicutes,4HJ21@91061|Bacilli,1ZDSK@1386|Bacillus 91061|Bacilli J protein with SCP PR1 domains ykwD - - - - - - - - - - - CAP k141_1856_1 1121413.JMKT01000009_gene2157 6.42e-34 130.0 COG4425@1|root,COG4425@2|Bacteria,1MXSU@1224|Proteobacteria 1224|Proteobacteria S membrane - - - - - - - - - - - - Abhydrolase_9,Abhydrolase_9_N k141_30311_1 218284.CCDN010000001_gene1502 1.22e-34 120.0 2E62M@1|root,330RR@2|Bacteria,1VF8M@1239|Firmicutes,4HPWY@91061|Bacilli,1ZITR@1386|Bacillus 91061|Bacilli S Belongs to the Tlp family tlp - - ko:K06434 - - - - ko00000 - - - - k141_27208_1 1279017.AQYJ01000026_gene67 1.01e-45 152.0 2B4XH@1|root,32REP@2|Bacteria,1RJ9F@1224|Proteobacteria,1T0SV@1236|Gammaproteobacteria,46BPI@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_32754_1 1042377.AFPJ01000009_gene330 7.84e-172 481.0 COG0500@1|root,COG2226@2|Bacteria 2|Bacteria Q methyltransferase - - 2.1.1.163,2.1.1.201 ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116,M00117 R04990,R04993,R06859,R08774,R09736 RC00003,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_11,Methyltransf_25 k141_18799_1 218284.CCDN010000001_gene1414 3.59e-30 115.0 COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,1TPE2@1239|Firmicutes,4H9WH@91061|Bacilli,1ZCWN@1386|Bacillus 91061|Bacilli P Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B,Rhodanese k141_18799_2 218284.CCDN010000001_gene1415 4.34e-53 169.0 COG2149@1|root,COG2149@2|Bacteria,1VEBE@1239|Firmicutes,4HP6Q@91061|Bacilli,1ZIBU@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF202) - - - ko:K00389 - - - - ko00000 - - - DUF202 k141_37479_1 1116375.VEJY3_10675 7.09e-281 769.0 COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria,1XSPH@135623|Vibrionales 135623|Vibrionales I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP fabF GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.179 ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt k141_37479_2 243277.VC_2020 1.92e-55 174.0 COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria,1S8X4@1236|Gammaproteobacteria,1XYA4@135623|Vibrionales 135623|Vibrionales IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis acpP GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - ko:K02078 - - - - ko00000,ko00001 - - - PP-binding k141_37479_3 870967.VIS19158_19627 7.31e-162 454.0 COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,1RMBB@1236|Gammaproteobacteria,1XSFH@135623|Vibrionales 135623|Vibrionales IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) fabG GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 k141_37479_4 1280001.BAOA01000086_gene3563 9.83e-207 573.0 COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,1RNH3@1236|Gammaproteobacteria,1XTJB@135623|Vibrionales 135623|Vibrionales I COG0331 (acyl-carrier-protein) S-malonyltransferase fabD - 2.3.1.39 ko:K00645 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082 R01626,R11671 RC00004,RC00039,RC02727 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyl_transf_1 k141_7874_1 930169.B5T_01080 1.31e-67 225.0 COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,1RN9H@1236|Gammaproteobacteria,1XHM0@135619|Oceanospirillales 135619|Oceanospirillales M Catalyzes cross-linking of the peptidoglycan cell wall mrdA - 3.4.16.4 ko:K05515 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - - PBP_dimer,Transpeptidase k141_16221_2 1294265.JCM21738_2699 3.08e-77 239.0 COG1071@1|root,COG1071@2|Bacteria,1TQDG@1239|Firmicutes,4H9PQ@91061|Bacilli,1ZBE0@1386|Bacillus 91061|Bacilli C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit pdhA - 1.2.4.1 ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh k141_37501_1 1123487.KB892868_gene1189 6.31e-105 325.0 COG2304@1|root,COG2304@2|Bacteria,1NT48@1224|Proteobacteria,2W0MY@28216|Betaproteobacteria 28216|Betaproteobacteria S oxidoreductase activity - - - - - - - - - - - - - k141_3093_3 1033743.CAES01000104_gene3485 3.87e-19 92.4 COG4926@1|root,COG4926@2|Bacteria,1TQHW@1239|Firmicutes,4HFA8@91061|Bacilli,26VV6@186822|Paenibacillaceae 91061|Bacilli S Prophage endopeptidase tail - - - - - - - - - - - - Prophage_tail k141_14150_1 1187848.AJYQ01000151_gene2452 1.67e-206 578.0 COG0477@1|root,COG2814@2|Bacteria,1MU9G@1224|Proteobacteria,1RM9G@1236|Gammaproteobacteria,1XV9G@135623|Vibrionales 135623|Vibrionales EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 k141_32778_1 218284.CCDN010000006_gene3542 1.59e-45 157.0 COG1979@1|root,COG1979@2|Bacteria,1TPS3@1239|Firmicutes,4HT1J@91061|Bacilli,1ZEGP@1386|Bacillus 91061|Bacilli C Iron-containing alcohol dehydrogenase - - - ko:K19955 - - - - ko00000,ko01000 - - - Fe-ADH k141_32778_2 218284.CCDN010000006_gene3543 1.86e-79 244.0 COG0583@1|root,COG0583@2|Bacteria,1TRYW@1239|Firmicutes,4H9T5@91061|Bacilli,1ZC6S@1386|Bacillus 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_4313_1 218284.CCDN010000002_gene1999 3.42e-133 397.0 COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,4HB12@91061|Bacilli,1ZCM9@1386|Bacillus 91061|Bacilli L ATP-dependent DNA helicase pcrA - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C k141_9244_2 1122194.AUHU01000002_gene2830 2.78e-74 242.0 COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,1S2IK@1236|Gammaproteobacteria,466ZA@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - - - - - - - - - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 k141_34092_1 218284.CCDN010000002_gene2063 7.57e-142 408.0 COG4129@1|root,COG4129@2|Bacteria,1UY2G@1239|Firmicutes,4HAWK@91061|Bacilli,1ZBAR@1386|Bacillus 91061|Bacilli S Aromatic acid exporter family member 1 - - - - - - - - - - - - ArAE_1 k141_7875_1 218284.CCDN010000006_gene3673 5.52e-94 284.0 COG0626@1|root,COG0626@2|Bacteria,1TPC7@1239|Firmicutes,4HAFQ@91061|Bacilli,1ZAR9@1386|Bacillus 91061|Bacilli E cystathionine - - 2.5.1.48 ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017 R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946 RC00020,RC00056,RC00069,RC00420,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000 - - - Cys_Met_Meta_PP k141_16222_1 218284.CCDN010000002_gene2237 1.6e-25 104.0 COG3275@1|root,COG3275@2|Bacteria,1VTXF@1239|Firmicutes,4H9Z1@91061|Bacilli,1ZBKQ@1386|Bacillus 91061|Bacilli T Histidine kinase lytS - 2.7.13.3 ko:K07704 ko02020,map02020 M00492 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - 5TM-5TMR_LYT,GAF_3,HATPase_c,His_kinase k141_23563_1 218284.CCDN010000002_gene2028 7.46e-67 202.0 COG2329@1|root,COG2329@2|Bacteria,1VCVN@1239|Firmicutes,4HKEU@91061|Bacilli,1ZI9B@1386|Bacillus 91061|Bacilli S Antibiotic biosynthesis monooxygenase - - 1.14.99.57 ko:K21481 - - - - ko00000,ko01000 - - - ABM k141_35348_1 639030.JHVA01000001_gene2131 2.44e-78 249.0 COG0504@1|root,COG0504@2|Bacteria,3Y2MH@57723|Acidobacteria,2JID4@204432|Acidobacteriia 204432|Acidobacteriia F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates pyrG - 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 - - - CTP_synth_N,GATase k141_20903_1 1279017.AQYJ01000026_gene112 1.12e-47 171.0 COG0210@1|root,COG0210@2|Bacteria,1MXWE@1224|Proteobacteria,1RP5D@1236|Gammaproteobacteria,466UN@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG0210 Superfamily I DNA and RNA helicases uvrD-2 - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C k141_20903_2 1453501.JELR01000001_gene2606 9.79e-76 232.0 2DFIW@1|root,32U5K@2|Bacteria,1N3SV@1224|Proteobacteria,1S9V3@1236|Gammaproteobacteria,468SS@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF4919) - - - - - - - - - - - - DUF4919 k141_31471_1 1298593.TOL_0015 1.62e-33 135.0 COG0668@1|root,COG0668@2|Bacteria,1MY0I@1224|Proteobacteria,1RQKY@1236|Gammaproteobacteria,1XJP8@135619|Oceanospirillales 135619|Oceanospirillales M COG0668 Small-conductance mechanosensitive channel - - - ko:K22044 - - - - ko00000,ko02000 1.A.23.3 - - MS_channel k141_22233_1 1123279.ATUS01000001_gene2469 4.41e-46 160.0 2CJ6B@1|root,32S9B@2|Bacteria,1N2I4@1224|Proteobacteria,1S8Z8@1236|Gammaproteobacteria,1J6QJ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Thermostable hemolysin - - - - - - - - - - - - T_hemolysin k141_3094_1 1042377.AFPJ01000014_gene1666 9.85e-16 74.7 2ACR0@1|root,312BP@2|Bacteria,1NG36@1224|Proteobacteria,1SH59@1236|Gammaproteobacteria,46BQC@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_11628_1 1294265.JCM21738_4559 1.08e-84 257.0 28JUG@1|root,2Z9JI@2|Bacteria,1UYYT@1239|Firmicutes,4HC3E@91061|Bacilli,1ZBYK@1386|Bacillus 91061|Bacilli S YaaC-like Protein yaaC - - - - - - - - - - - YaaC k141_19870_1 218284.CCDN010000005_gene3228 7.34e-05 43.9 COG3857@1|root,COG3857@2|Bacteria,1TQJW@1239|Firmicutes,4HAY6@91061|Bacilli,1ZC70@1386|Bacillus 91061|Bacilli L ATP-dependent helicase deoxyribonuclease subunit B rexB GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0004527,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.6.4.12 ko:K16899 - - - - ko00000,ko01000,ko03400 - - - Exonuc_V_gamma,PDDEXK_1,UvrD_C k141_17356_1 1123236.KB899381_gene2969 1.54e-69 212.0 COG0835@1|root,COG0835@2|Bacteria,1RAH1@1224|Proteobacteria,1SYDF@1236|Gammaproteobacteria,466IY@72275|Alteromonadaceae 1236|Gammaproteobacteria NT COG0835 Chemotaxis signal transduction protein cheW - - ko:K03408 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - CheW k141_17356_2 1537994.JQFW01000015_gene1812 1.01e-28 110.0 COG0835@1|root,COG0835@2|Bacteria,1MYHY@1224|Proteobacteria,1S2TC@1236|Gammaproteobacteria,466MB@72275|Alteromonadaceae 1236|Gammaproteobacteria NT Two component signalling adaptor domain VP2226 - - ko:K03408 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - CheW k141_4314_1 218284.CCDN010000001_gene808 3.05e-86 266.0 2BAY9@1|root,324E2@2|Bacteria,1V8TN@1239|Firmicutes,4HJ42@91061|Bacilli,1ZESD@1386|Bacillus 91061|Bacilli - - yqgU - - - - - - - - - - - - k141_35349_1 42565.FP66_13430 3.88e-84 270.0 COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,1RM9X@1236|Gammaproteobacteria,1XH9T@135619|Oceanospirillales 135619|Oceanospirillales J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB - - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N,IF2_assoc k141_35349_2 1118153.MOY_14002 2.82e-15 70.9 COG0858@1|root,COG0858@2|Bacteria,1MZPE@1224|Proteobacteria,1S9AF@1236|Gammaproteobacteria,1XKKG@135619|Oceanospirillales 135619|Oceanospirillales J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA rbfA - - ko:K02834 - - - - ko00000,ko03009 - - - RBFA k141_34093_1 45157.CMM274CT 2.25e-72 239.0 COG1190@1|root,KOG1885@2759|Eukaryota 2759|Eukaryota J lysyl-tRNA aminoacylation - - 6.1.1.6 ko:K04567 ko00970,map00970 M00359,M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2,tRNA_anti-codon k141_17357_1 1279017.AQYJ01000027_gene1546 2.5e-73 233.0 COG3515@1|root,COG3515@2|Bacteria,1MY80@1224|Proteobacteria,1T0A1@1236|Gammaproteobacteria,466QN@72275|Alteromonadaceae 1236|Gammaproteobacteria S ImpA, N-terminal, type VI secretion system impA - - ko:K11902 ko02025,map02025 M00334 - - ko00000,ko00001,ko00002,ko02044 - - - ImpA_N k141_36284_1 218284.CCDN010000001_gene630 4.32e-93 278.0 COG0739@1|root,COG0739@2|Bacteria,1TSQI@1239|Firmicutes,4HFC8@91061|Bacilli,1ZFJN@1386|Bacillus 91061|Bacilli M COG0739 Membrane proteins related to metalloendopeptidases spoIVFA - - ko:K06401 - - - - ko00000 - - - Peptidase_M23 k141_3095_1 1453501.JELR01000002_gene1431 2.47e-65 215.0 COG0427@1|root,COG1670@1|root,COG0427@2|Bacteria,COG1670@2|Bacteria,1MUGE@1224|Proteobacteria,1RP19@1236|Gammaproteobacteria,46429@72275|Alteromonadaceae 1236|Gammaproteobacteria C acetyl-CoA hydrolase - - - ko:K18288 ko00660,map00660 - R02407,R10600 RC00012,RC00014 ko00000,ko00001,ko01000 - - - AcetylCoA_hyd_C,AcetylCoA_hydro,Acetyltransf_1,Acetyltransf_3 k141_23565_1 1294265.JCM21738_1204 1.27e-179 530.0 COG0553@1|root,COG4715@1|root,COG0553@2|Bacteria,COG4715@2|Bacteria,1TPFZ@1239|Firmicutes,4HAIF@91061|Bacilli,1ZBZT@1386|Bacillus 91061|Bacilli L COG0553 Superfamily II DNA RNA helicases, SNF2 family snf - - - - - - - - - - - Helicase_C,SNF2_N,SNF2_assoc,SWIM k141_4315_1 997296.PB1_07312 6.62e-98 297.0 COG0486@1|root,COG0486@2|Bacteria,1TPJF@1239|Firmicutes,4HA06@91061|Bacilli,1ZBTZ@1386|Bacillus 91061|Bacilli S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 mnmE - - ko:K03650 - - R08701 RC00053,RC00209,RC00870 ko00000,ko01000,ko03016 - - - MMR_HSR1,MnmE_helical,TrmE_N k141_7876_2 1297569.MESS2_1020028 4.72e-90 281.0 COG1861@1|root,COG1861@2|Bacteria,1QU5J@1224|Proteobacteria,2U0ZH@28211|Alphaproteobacteria 28211|Alphaproteobacteria L DDE (Asp,Asp,Glu) domain - - - - - - - - - - - - DDE_Tnp_1_4 k141_32781_1 218284.CCDN010000002_gene2084 1.54e-94 283.0 COG3396@1|root,COG3396@2|Bacteria,1TRTS@1239|Firmicutes,4HAII@91061|Bacilli,1ZC82@1386|Bacillus 91061|Bacilli S Phenylacetic acid catabolic protein paaA - 1.14.13.149 ko:K02609 ko00360,ko01120,map00360,map01120 - R09838 RC02690 ko00000,ko00001,ko01000 - - - PaaA_PaaC k141_25898_1 1219076.N646_3357 2.26e-52 169.0 COG0366@1|root,COG0366@2|Bacteria,1QJND@1224|Proteobacteria,1THP3@1236|Gammaproteobacteria,1XWZW@135623|Vibrionales 135623|Vibrionales M Alpha amylase catalytic - - - - - - - - - - - - - k141_25898_2 1348635.BBJY01000001_gene2447 1.67e-73 233.0 2C19D@1|root,2Z7PA@2|Bacteria,1MY1F@1224|Proteobacteria,1RQ3A@1236|Gammaproteobacteria,1XUFJ@135623|Vibrionales 135623|Vibrionales S Maltose operon periplasmic protein precursor (MalM) malM - - ko:K05775 - - - - ko00000 - - - MalM k141_25898_3 1348635.BBJY01000001_gene2448 7.9e-187 534.0 COG4580@1|root,COG4580@2|Bacteria,1MX77@1224|Proteobacteria,1RPMF@1236|Gammaproteobacteria,1XU0M@135623|Vibrionales 135623|Vibrionales M Involved in the transport of maltose and maltodextrins lamB GO:0003674,GO:0005215,GO:0005363,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015154,GO:0015157,GO:0015267,GO:0015288,GO:0015481,GO:0015766,GO:0015768,GO:0015772,GO:0022803,GO:0022829,GO:0022857,GO:0034219,GO:0051179,GO:0051234,GO:0055085,GO:0071702 - ko:K02024 - - - - ko00000,ko02000 1.B.3.1.1 - - LamB k141_27250_1 491952.Mar181_0235 1.83e-78 244.0 COG3191@1|root,COG3191@2|Bacteria,1MWDP@1224|Proteobacteria,1RYNM@1236|Gammaproteobacteria 1236|Gammaproteobacteria EQ peptidase S58 DmpA dmpA - 3.4.11.19 ko:K01266 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S58 k141_14990_2 218284.CCDN010000001_gene1104 2.05e-15 72.8 28J08@1|root,2Z8XG@2|Bacteria,1V177@1239|Firmicutes,4HCWC@91061|Bacilli,1ZCRV@1386|Bacillus 91061|Bacilli - - yphF - - - - - - - - - - - DUF3939 k141_10408_1 218284.CCDN010000001_gene1658 1.33e-140 400.0 COG3279@1|root,COG3279@2|Bacteria,1V14X@1239|Firmicutes,4HGFK@91061|Bacilli,1ZAPX@1386|Bacillus 91061|Bacilli T LytTr DNA-binding domain natR - - ko:K02477,ko:K11641 ko02020,map02020 M00494 - - ko00000,ko00001,ko00002,ko02022 - - - LytTR,Response_reg k141_19871_1 1123054.KB907702_gene1471 3.35e-14 74.7 2C3QV@1|root,2Z7YP@2|Bacteria,1MXAM@1224|Proteobacteria,1RNIA@1236|Gammaproteobacteria,1X0PU@135613|Chromatiales 135613|Chromatiales S Alginate export - - - - - - - - - - - - - k141_19871_2 1279017.AQYJ01000027_gene1667 7.75e-94 285.0 COG2223@1|root,COG2223@2|Bacteria,1MU27@1224|Proteobacteria,1RMUK@1236|Gammaproteobacteria,4652C@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG2223 Nitrate nitrite transporter narK1 - - ko:K02575 ko00910,map00910 M00615 - - ko00000,ko00001,ko00002,ko02000 2.A.1.8 - - MFS_1 k141_889_1 1453501.JELR01000001_gene3045 2.97e-76 239.0 COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,1RMQ3@1236|Gammaproteobacteria,464K0@72275|Alteromonadaceae 1236|Gammaproteobacteria M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) murG GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008194,GO:0008375,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0050511,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.4.1.227 ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 - R05032,R05662 RC00005,RC00049 ko00000,ko00001,ko01000,ko01011 - GT28 iSFV_1184.SFV_0083,iSF_1195.SF0087,iSFxv_1172.SFxv_0091,iS_1188.S0089 Glyco_tran_28_C,Glyco_transf_28 k141_889_2 1453501.JELR01000001_gene3044 8.12e-302 828.0 COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,1RN88@1236|Gammaproteobacteria,465HW@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the MurCDEF family murC GO:0000166,GO:0000270,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008763,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0035639,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0046872,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.2.8 ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - iECP_1309.ECP_0093 Mur_ligase,Mur_ligase_C,Mur_ligase_M k141_889_3 1279017.AQYJ01000024_gene1089 6.59e-106 315.0 COG1589@1|root,COG1589@2|Bacteria,1N0T7@1224|Proteobacteria,1S9FJ@1236|Gammaproteobacteria,467QJ@72275|Alteromonadaceae 1236|Gammaproteobacteria D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly ftsQ GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0042802,GO:0043093,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 - ko:K03589 ko04112,map04112 - - - ko00000,ko00001,ko03036 - - - FtsQ,POTRA_1 k141_9246_1 1034347.CAHJ01000057_gene887 1e-54 193.0 COG3540@1|root,COG3540@2|Bacteria,1VS25@1239|Firmicutes,4HUTD@91061|Bacilli,1ZD0T@1386|Bacillus 91061|Bacilli P Alkaline phosphatase - - - - - - - - - - - - PhoD k141_20905_1 316067.Geob_1707 1.38e-17 80.1 COG0861@1|root,COG0861@2|Bacteria,1MWC9@1224|Proteobacteria,42MZB@68525|delta/epsilon subdivisions,2WKV4@28221|Deltaproteobacteria 28221|Deltaproteobacteria P PFAM Integral membrane protein TerC - - - - - - - - - - - - TerC k141_3096_1 1042377.AFPJ01000028_gene2210 8.75e-89 283.0 COG0834@1|root,COG4623@1|root,COG0834@2|Bacteria,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,1RM8W@1236|Gammaproteobacteria,467JF@72275|Alteromonadaceae 1236|Gammaproteobacteria EMT Bacterial periplasmic substrate-binding proteins - GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - ko:K18691 - - - - ko00000,ko01000,ko01011 - - - SBP_bac_3,SLT k141_27251_1 1208321.D104_10365 1.07e-91 276.0 COG0179@1|root,COG0179@2|Bacteria,1MV0V@1224|Proteobacteria,1RNYV@1236|Gammaproteobacteria,1XH60@135619|Oceanospirillales 135619|Oceanospirillales Q Fumarylacetoacetate (FAA) hydrolase - - 3.7.1.2 ko:K16171 ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120 M00044 R01364 RC00326,RC00446 ko00000,ko00001,ko00002,ko01000 - - - FAA_hydrolase k141_12853_1 1116375.VEJY3_13095 8.47e-97 283.0 COG1854@1|root,COG1854@2|Bacteria,1MWQF@1224|Proteobacteria,1RMDZ@1236|Gammaproteobacteria,1XUCG@135623|Vibrionales 135623|Vibrionales H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) luxS GO:0008150,GO:0009372,GO:0009987,GO:0044764,GO:0051704 4.4.1.21 ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 M00609 R01291 RC00069,RC01929 ko00000,ko00001,ko00002,ko01000 - - - LuxS k141_12853_2 1116375.VEJY3_13100 2.45e-145 409.0 COG4764@1|root,COG4764@2|Bacteria,1MVRK@1224|Proteobacteria,1RQ79@1236|Gammaproteobacteria,1XTVN@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria - - - - - - - - - - - - - k141_12853_3 1116375.VEJY3_13105 0.0 963.0 COG2918@1|root,COG2918@2|Bacteria,1MW9B@1224|Proteobacteria,1RPNQ@1236|Gammaproteobacteria,1XTNN@135623|Vibrionales 135623|Vibrionales H Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily gshA GO:0003674,GO:0003824,GO:0004357,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0019184,GO:0034641,GO:0042398,GO:0043043,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0051186,GO:0051188,GO:0071704,GO:1901564,GO:1901566,GO:1901576 6.3.2.2 ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 M00118 R00894,R10993 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - Glu_cys_ligase k141_12853_4 1116375.VEJY3_13110 0.0 1192.0 COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,1RN05@1236|Gammaproteobacteria,1XU3E@135623|Vibrionales 135623|Vibrionales S Insulinase (Peptidase family M16) - - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C k141_22236_1 1279017.AQYJ01000025_gene474 6.27e-114 340.0 COG3259@1|root,COG3259@2|Bacteria,1QUQ7@1224|Proteobacteria,1T20U@1236|Gammaproteobacteria,4654F@72275|Alteromonadaceae 1236|Gammaproteobacteria C Nickel-dependent hydrogenase hoxH - - - - - - - - - - - NiFeSe_Hases k141_22236_2 1279017.AQYJ01000025_gene473 2.34e-18 80.9 COG0680@1|root,COG0680@2|Bacteria,1NA38@1224|Proteobacteria,1SFXD@1236|Gammaproteobacteria 1236|Gammaproteobacteria C maturation - - - - - - - - - - - - HycI k141_25899_1 218284.CCDN010000005_gene3298 1.01e-45 153.0 COG0061@1|root,COG0061@2|Bacteria,1TRB3@1239|Firmicutes,4HB08@91061|Bacilli,1ZAQP@1386|Bacillus 91061|Bacilli G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP nadK GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 - R00104 RC00002,RC00078 ko00000,ko00001,ko01000 - - iSB619.SA_RS04895 NAD_kinase k141_36285_1 1294265.JCM21738_1723 8.63e-82 257.0 COG5434@1|root,COG5434@2|Bacteria,1TSDM@1239|Firmicutes,4HF01@91061|Bacilli,1ZB2S@1386|Bacillus 91061|Bacilli M Pectate lyase superfamily protein yobO - - - - - - - - - - - Pectate_lyase_3,Peptidase_G2 k141_37504_2 1122604.JONR01000010_gene3925 7.81e-05 49.7 COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,1RMFZ@1236|Gammaproteobacteria,1X55Z@135614|Xanthomonadales 135614|Xanthomonadales M Lysin motif - - - - - - - - - - - - LysM,SLT k141_27252_1 498848.TaqDRAFT_4327 7.27e-71 229.0 COG0702@1|root,COG0702@2|Bacteria,1WJH3@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus GM Protein of unknown function (DUF2867) - - - - - - - - - - - - DUF2867,NAD_binding_10,NmrA k141_4329_1 218284.CCDN010000005_gene3303 4.44e-22 90.5 COG2318@1|root,COG2318@2|Bacteria 2|Bacteria S DinB family - - - - - - - - - - - - DinB_2 k141_4329_2 218284.CCDN010000005_gene3304 9.97e-41 140.0 COG0623@1|root,COG0623@2|Bacteria,1TPVD@1239|Firmicutes,4H9YN@91061|Bacilli,1ZAP0@1386|Bacillus 91061|Bacilli I Enoyl- acyl-carrier-protein reductase NADH fabI GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006950,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0033554,GO:0036094,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051716,GO:0055114,GO:0065003,GO:0070417,GO:0071704,GO:0071840,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.3.1.10,1.3.1.9 ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 M00083,M00572 R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671 RC00052,RC00076,RC00120 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 k141_36298_1 691883.XP_009495075.1 1.02e-48 167.0 COG1132@1|root,KOG0055@2759|Eukaryota,39XGF@33154|Opisthokonta 33154|Opisthokonta Q ABC transporter - - - - - - - - - - - - ABC_tran k141_16242_2 1132442.KB889752_gene2507 7.91e-81 256.0 COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,4H9RY@91061|Bacilli,1ZBR9@1386|Bacillus 91061|Bacilli S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid ytgP GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03328 - - - - ko00000 2.A.66.2 - - Polysacc_synt,Polysacc_synt_C k141_14172_1 1294265.JCM21738_3395 1.42e-84 253.0 2E3R1@1|root,32YNU@2|Bacteria,1VEND@1239|Firmicutes,4HNII@91061|Bacilli,1ZFAW@1386|Bacillus 91061|Bacilli S Anti-sigma factor N-terminus rsgI - - - - - - - - - - - RsgI_N k141_18850_1 1116375.VEJY3_23006 2.63e-69 223.0 COG2072@1|root,COG2072@2|Bacteria,1MU71@1224|Proteobacteria,1RP8X@1236|Gammaproteobacteria 1236|Gammaproteobacteria P flavoprotein involved in K transport - - - - - - - - - - - - FMO-like,NAD_binding_8,Pyr_redox_3 k141_32802_1 218284.CCDN010000008_gene4202 5.68e-80 243.0 COG0491@1|root,COG0491@2|Bacteria,1TRED@1239|Firmicutes,4HAP2@91061|Bacilli,1ZAYX@1386|Bacillus 91061|Bacilli S COG0491 Zn-dependent hydrolases, including glyoxylases ytnP - - - - - - - - - - - Lactamase_B k141_23600_1 218284.CCDN010000002_gene2114 5.7e-173 487.0 COG3508@1|root,COG3508@2|Bacteria,1UYZ0@1239|Firmicutes,4HCCC@91061|Bacilli,1ZC6Q@1386|Bacillus 91061|Bacilli Q homogentisate 12-dioxygenase hmgA - 1.13.11.5 ko:K00451 ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120 M00044 R02519 RC00737 ko00000,ko00001,ko00002,ko01000 - - - HgmA k141_909_2 1279017.AQYJ01000024_gene941 3.15e-76 231.0 COG0454@1|root,COG0456@2|Bacteria,1RH71@1224|Proteobacteria,1S5XH@1236|Gammaproteobacteria,467WX@72275|Alteromonadaceae 1236|Gammaproteobacteria K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1 k141_5893_2 688270.Celal_3633 1.87e-154 443.0 COG0667@1|root,COG0667@2|Bacteria,4NFCN@976|Bacteroidetes,1HWKD@117743|Flavobacteriia,1F9S9@104264|Cellulophaga 976|Bacteroidetes C Aldo/keto reductase family - - - ko:K19265 - - - - ko00000,ko01000 - - - Aldo_ket_red k141_5893_3 203122.Sde_3710 4.91e-156 453.0 COG3867@1|root,COG3867@2|Bacteria,1R6E6@1224|Proteobacteria,1S03B@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Arabinogalactan endo-beta-1,4-galactanase - - 3.2.1.89 ko:K01224 - - - - ko00000,ko01000 - - - Glyco_hydro_53,RicinB_lectin_2 k141_10530_1 471223.GWCH70_0143 8.89e-17 77.4 COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,4HCFI@91061|Bacilli,1WF21@129337|Geobacillus 91061|Bacilli J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs truA GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 ko:K06173 - - - - ko00000,ko01000,ko03016 - - - PseudoU_synth_1 k141_29529_1 1517681.HW45_22610 5.62e-58 192.0 COG1360@1|root,COG1360@2|Bacteria,1MW1Y@1224|Proteobacteria,1RPQ9@1236|Gammaproteobacteria,1XV9X@135623|Vibrionales 135623|Vibrionales N Membrane MotB of proton-channel complex MotA/MotB - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02557 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - MotB_plug,OmpA k141_15156_1 223926.28808052 1.55e-200 567.0 COG0352@1|root,COG0352@2|Bacteria,1QTW3@1224|Proteobacteria,1T1YB@1236|Gammaproteobacteria,1XSWF@135623|Vibrionales 135623|Vibrionales H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) thiE - 2.5.1.3 ko:K00788 ko00730,ko01100,map00730,map01100 M00127 R03223,R10712 RC00224,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 - - - TMP-TENI k141_15156_2 223926.28808053 0.0 1262.0 COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,1RP1F@1236|Gammaproteobacteria,1XSWD@135623|Vibrionales 135623|Vibrionales H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction thiC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 ko:K03147 ko00730,ko01100,map00730,map01100 M00127 R03472 RC03251,RC03252 ko00000,ko00001,ko00002,ko01000 - - - ThiC-associated,ThiC_Rad_SAM k141_15156_3 1136163.M565_ctg4P270 1.1e-78 234.0 COG0239@1|root,COG0239@2|Bacteria,1MZNH@1224|Proteobacteria,1S8RQ@1236|Gammaproteobacteria,1XXA0@135623|Vibrionales 135623|Vibrionales D Important for reducing fluoride concentration in the cell, thus reducing its toxicity crcB GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - ko:K06199 - - - - ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 - - CRCB k141_15156_4 223926.28805017 0.0 964.0 COG0059@1|root,COG0059@2|Bacteria,1MV7M@1224|Proteobacteria,1RNA8@1236|Gammaproteobacteria,1XSFQ@135623|Vibrionales 135623|Vibrionales EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate ilvC GO:0003674,GO:0003824,GO:0004455,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.86 ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R03051,R04439,R04440,R05068,R05069,R05071 RC00726,RC00836,RC00837,RC01726 ko00000,ko00001,ko00002,ko01000 - - - IlvC,IlvN k141_15156_5 223926.28805016 1.04e-191 534.0 COG0583@1|root,COG0583@2|Bacteria,1MZX1@1224|Proteobacteria,1RNFR@1236|Gammaproteobacteria,1XSJR@135623|Vibrionales 135623|Vibrionales K Transcriptional regulator ilvY - - ko:K02521 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate k141_2058_2 1301100.HG529262_gene699 3.52e-25 108.0 COG1073@1|root,COG1073@2|Bacteria,1V2C5@1239|Firmicutes,25EB6@186801|Clostridia,36F2M@31979|Clostridiaceae 186801|Clostridia P Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_5,Rhodanese k141_24826_1 926569.ANT_08030 6.14e-36 140.0 COG1361@1|root,COG3764@1|root,COG1361@2|Bacteria,COG3764@2|Bacteria,2G854@200795|Chloroflexi 200795|Chloroflexi M Domain of unknown function DUF11 - - - - - - - - - - - - DUF11 k141_17539_1 1246484.D479_14957 1.95e-58 191.0 COG1131@1|root,COG1131@2|Bacteria,1TPMQ@1239|Firmicutes,4IPMF@91061|Bacilli,3NDM0@45667|Halobacillus 91061|Bacilli V Domain of unknown function (DUF4162) - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 k141_11886_2 1121929.KB898675_gene2225 1.49e-44 153.0 COG0352@1|root,COG0352@2|Bacteria,1V6KJ@1239|Firmicutes,4HIM9@91061|Bacilli,470VK@74385|Gracilibacillus 91061|Bacilli H Thiamine monophosphate synthase tenI - 2.5.1.3,5.3.99.10 ko:K00788,ko:K10810 ko00730,ko01100,map00730,map01100 M00127 R03223,R09977,R10712 RC00224,RC02766,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000,ko03000 - - - TMP-TENI k141_22565_1 1294265.JCM21738_4991 2.45e-73 220.0 COG1937@1|root,COG1937@2|Bacteria,1VEF5@1239|Firmicutes,4HJ3J@91061|Bacilli,1ZH3J@1386|Bacillus 91061|Bacilli S protein conserved in bacteria - - - ko:K21600 - - - - ko00000,ko03000 - - - Trns_repr_metal k141_22565_3 1294265.JCM21738_4986 7.59e-37 135.0 COG2027@1|root,COG2027@2|Bacteria,1TQFQ@1239|Firmicutes,4HA3X@91061|Bacilli,1ZBNY@1386|Bacillus 91061|Bacilli M D-alanyl-D-alanine carboxypeptidase dacC - 3.4.16.4 ko:K07259 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - Peptidase_S13 k141_36435_1 1453501.JELR01000002_gene875 2.35e-149 425.0 COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,1RMJJ@1236|Gammaproteobacteria,465VY@72275|Alteromonadaceae 1236|Gammaproteobacteria KT Response regulator of the LytR AlgR family - - - ko:K02477 - - - - ko00000,ko02022 - - - LytTR,Response_reg k141_35608_2 1279017.AQYJ01000029_gene3405 1.13e-91 285.0 COG3115@1|root,COG3115@2|Bacteria,1MVHR@1224|Proteobacteria,1RMDB@1236|Gammaproteobacteria,4673V@72275|Alteromonadaceae 1236|Gammaproteobacteria D Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins zipA GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0022402,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032506,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 - ko:K03528 - - - - ko00000,ko03036 - - - ZipA_C k141_21078_1 218284.CCDN010000003_gene2962 3.46e-155 447.0 COG1982@1|root,COG1982@2|Bacteria,1TNZ9@1239|Firmicutes,4HBGC@91061|Bacilli,1ZBKS@1386|Bacillus 91061|Bacilli E Orn Lys Arg decarboxylase yaaO - - - - - - - - - - - OKR_DC_1,OKR_DC_1_C k141_29530_1 1453501.JELR01000002_gene185 2.08e-143 410.0 COG0697@1|root,COG0697@2|Bacteria,1PGSE@1224|Proteobacteria,1RMZY@1236|Gammaproteobacteria,4673D@72275|Alteromonadaceae 1236|Gammaproteobacteria EG EamA-like transporter family yhbE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - EamA k141_30452_1 42256.RradSPS_1903 3.17e-36 131.0 COG0139@1|root,COG0140@1|root,COG0139@2|Bacteria,COG0140@2|Bacteria,2IKKU@201174|Actinobacteria,4CQAR@84995|Rubrobacteria 84995|Rubrobacteria E Histidine biosynthesis bifunctional protein HisIE hisI - 3.5.4.19,3.6.1.31 ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035,R04037 RC00002,RC01055 ko00000,ko00001,ko00002,ko01000 - - - PRA-CH,PRA-PH k141_17540_1 574376.BAMA_05670 2.29e-64 222.0 COG1404@1|root,COG1404@2|Bacteria,1TPH1@1239|Firmicutes,4HBQH@91061|Bacilli,1ZBS0@1386|Bacillus 91061|Bacilli O Belongs to the peptidase S8 family prtS - 3.4.21.110,3.4.21.96 ko:K01361,ko:K08652 - - - - ko00000,ko01000,ko01002,ko03110 - - - FIVAR,Gram_pos_anchor,Inhibitor_I9,PA,Peptidase_S8,SLH,YSIRK_signal,fn3_5 k141_24827_1 218284.CCDN010000001_gene607 1.02e-136 393.0 COG2334@1|root,COG2334@2|Bacteria,1V54J@1239|Firmicutes,4HH2K@91061|Bacilli,1ZB97@1386|Bacillus 91061|Bacilli S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response ysxE - - - - - - - - - - - APH k141_26153_1 1219076.N646_1529 8.6e-225 625.0 COG0213@1|root,COG0213@2|Bacteria,1MV3H@1224|Proteobacteria,1RPTG@1236|Gammaproteobacteria,1XSGE@135623|Vibrionales 135623|Vibrionales F The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis deoA GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009032,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0034641,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360 2.4.2.4 ko:K00758 ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219 - R01570,R02484,R08222,R08230 RC00063 ko00000,ko00001,ko01000 - - - Glycos_trans_3N,Glycos_transf_3,PYNP_C k141_15157_1 1042377.AFPJ01000036_gene1134 3.66e-88 283.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MV8W@1224|Proteobacteria,1RMQA@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Outer membrane receptor proteins mostly Fe transport - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_37718_5 1515746.HR45_07230 0.0 980.0 COG4974@1|root,COG4974@2|Bacteria,1QVZC@1224|Proteobacteria,1T2P4@1236|Gammaproteobacteria,2QET5@267890|Shewanellaceae 1236|Gammaproteobacteria L Phage integrase family - - - - - - - - - - - - Phage_integrase k141_37718_6 1116375.VEJY3_10730 0.0 944.0 COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,1RMCN@1236|Gammaproteobacteria,1XSDS@135623|Vibrionales 135623|Vibrionales P COG0659 Sulfate permease and related transporters (MFS superfamily) - - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - STAS,Sulfate_transp k141_37718_7 223926.28807055 0.0 1364.0 COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,1RMDS@1236|Gammaproteobacteria,1XTUQ@135623|Vibrionales 135623|Vibrionales J Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs rne - 3.1.26.12 ko:K08300 ko03018,map03018 M00394 - - ko00000,ko00001,ko00002,ko01000,ko03009,ko03019 - - - RNase_E_G,S1 k141_37718_8 1219076.N646_1137 1.95e-221 611.0 COG0564@1|root,COG0564@2|Bacteria,1MVDX@1224|Proteobacteria,1RPAN@1236|Gammaproteobacteria,1XT4V@135623|Vibrionales 135623|Vibrionales J Responsible for synthesis of pseudouridine from uracil rluC GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.24 ko:K06179 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 k141_20146_2 1453501.JELR01000002_gene374 9.66e-70 218.0 COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,1RM8G@1236|Gammaproteobacteria,4642K@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives folP GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042221,GO:0042364,GO:0042398,GO:0042493,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046655,GO:0046656,GO:0050896,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.15 ko:K00796 ko00790,ko01100,map00790,map01100 M00126,M00841 R03066,R03067 RC00121,RC00842 ko00000,ko00001,ko00002,ko01000 - - iECO103_1326.ECO103_3924,iPC815.YPO3501 Pterin_bind k141_29559_2 218284.CCDN010000004_gene3045 4.48e-155 441.0 COG1181@1|root,COG1181@2|Bacteria,1TP2Y@1239|Firmicutes,4H9KB@91061|Bacilli,1ZDA3@1386|Bacillus 91061|Bacilli F Belongs to the D-alanine--D-alanine ligase family ddl - 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Dala_Dala_lig_C,Dala_Dala_lig_N k141_30469_2 1279017.AQYJ01000028_gene2424 5.56e-53 171.0 COG5622@1|root,COG5622@2|Bacteria,1N6XP@1224|Proteobacteria,1SCD9@1236|Gammaproteobacteria,4691R@72275|Alteromonadaceae 1236|Gammaproteobacteria N Protein required for attachment to host cells - - - - - - - - - - - - Host_attach k141_17569_1 218284.CCDN010000004_gene3127 1.66e-185 522.0 COG0044@1|root,COG0044@2|Bacteria,1TPI6@1239|Firmicutes,4HAA9@91061|Bacilli,1ZE4P@1386|Bacillus 91061|Bacilli F Catalyzes the hydrolytic cleavage of a subset of L- isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation iadA - - ko:K01305 - - - - ko00000,ko01000,ko01002 - - - Amidohydro_1,Amidohydro_3 k141_37719_2 240302.BN982_03286 2.72e-25 95.1 2DPTX@1|root,333CM@2|Bacteria,1UES7@1239|Firmicutes,4I5NH@91061|Bacilli,3NFHF@45667|Halobacillus 91061|Bacilli S Protein of unknown function (DUF3311) - - - - - - - - - - - - DUF3311 k141_36452_2 218284.CCDN010000005_gene3295 1.03e-42 146.0 COG4116@1|root,COG4116@2|Bacteria,1VA56@1239|Firmicutes,4HMNE@91061|Bacilli,1ZH0U@1386|Bacillus 91061|Bacilli S protein conserved in bacteria yjbK - - - - - - - - - - - CYTH k141_10546_1 1042377.AFPJ01000007_gene1866 1.17e-131 397.0 COG1770@1|root,COG1770@2|Bacteria,1MUED@1224|Proteobacteria,1RMSV@1236|Gammaproteobacteria,464IJ@72275|Alteromonadaceae 1236|Gammaproteobacteria E Prolyl oligopeptidase, N-terminal beta-propeller domain ptrB GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0070011,GO:0070012,GO:0071704,GO:0140096,GO:1901564 3.4.21.83 ko:K01354 ko05142,ko05143,map05142,map05143 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S9,Peptidase_S9_N k141_31610_1 589865.DaAHT2_0366 6.61e-81 268.0 COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,42MNH@68525|delta/epsilon subdivisions,2WJ4G@28221|Deltaproteobacteria,2MINK@213118|Desulfobacterales 28221|Deltaproteobacteria L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA priA - - ko:K04066 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,ResIII k141_20148_1 326442.PSHAa2738 6.83e-19 84.7 COG2188@1|root,COG2188@2|Bacteria,1MVFM@1224|Proteobacteria,1RNPE@1236|Gammaproteobacteria,2Q0HT@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria K histidine utilization repressor hutC - - ko:K05836 - - - - ko00000,ko03000 - - - GntR,UTRA k141_29561_2 218284.CCDN010000006_gene3651 8.66e-65 199.0 COG1950@1|root,COG1950@2|Bacteria,1VF4I@1239|Firmicutes,4HNXP@91061|Bacilli,1ZI79@1386|Bacillus 91061|Bacilli S Membrane yvlD - - ko:K08972 - - - - ko00000 - - - Phage_holin_4_2 k141_1172_1 1294265.JCM21738_5513 2.7e-51 167.0 2EHES@1|root,33B6Q@2|Bacteria,1VNN8@1239|Firmicutes,4HRDX@91061|Bacilli,1ZFFJ@1386|Bacillus 91061|Bacilli S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) yutC - - - - - - - - - - - Spore_YhcN_YlaJ k141_1172_2 1294265.JCM21738_4539 5.84e-161 454.0 COG0320@1|root,COG0320@2|Bacteria,1TQM4@1239|Firmicutes,4H9SW@91061|Bacilli,1ZB5D@1386|Bacillus 91061|Bacilli H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives lipA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 ko:K03644 ko00785,ko01100,map00785,map01100 - R07767,R07768 RC01978 ko00000,ko00001,ko01000 - - - LIAS_N,Radical_SAM k141_16470_1 1453501.JELR01000001_gene3236 6.85e-247 685.0 2C612@1|root,32RGH@2|Bacteria,1RGYZ@1224|Proteobacteria,1S8MM@1236|Gammaproteobacteria,46BBZ@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_37720_1 1453501.JELR01000001_gene2410 1.13e-107 336.0 COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,1RN05@1236|Gammaproteobacteria,464MR@72275|Alteromonadaceae 1236|Gammaproteobacteria S Insulinase (Peptidase family M16) pqqL - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C k141_36453_1 379066.GAU_2797 5.94e-16 77.4 COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,1ZT89@142182|Gemmatimonadetes 142182|Gemmatimonadetes C Transketolase, pyrimidine binding domain - - 1.2.4.4 ko:K11381 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 M00036 R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00027,RC00627,RC02743,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh,Transket_pyr,Transketolase_C k141_36453_2 290397.Adeh_3779 4.31e-13 68.2 COG2316@1|root,COG2316@2|Bacteria,1RA50@1224|Proteobacteria,42QZZ@68525|delta/epsilon subdivisions,2WMUN@28221|Deltaproteobacteria,2Z0YN@29|Myxococcales 28221|Deltaproteobacteria S Metal dependent phosphohydrolases with conserved 'HD' motif. - - - - - - - - - - - - HD k141_28157_2 1122164.JHWF01000003_gene2058 6.56e-07 53.1 COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,1S5WR@1236|Gammaproteobacteria,1JEHG@118969|Legionellales 118969|Legionellales O Belongs to the thioredoxin family trxA - - ko:K03671 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - Thioredoxin k141_28157_3 1279017.AQYJ01000023_gene3148 1.42e-94 283.0 COG0491@1|root,COG0491@2|Bacteria 2|Bacteria GM Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - - - - - - - - - - Lactamase_B k141_20149_1 1453501.JELR01000002_gene1252 2.43e-119 362.0 COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,1RPZ7@1236|Gammaproteobacteria,464GR@72275|Alteromonadaceae 1236|Gammaproteobacteria L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA priA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006276,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0010332,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042221,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0046677,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - ko:K04066 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,ResIII k141_7958_1 218284.CCDN010000010_gene4331 1.95e-73 221.0 2BVDP@1|root,32QTK@2|Bacteria,1V9E2@1239|Firmicutes,4HJ1S@91061|Bacilli,1ZFUF@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2521) ybaK - - - - - - - - - - - DUF2521 k141_31611_1 1434929.X946_3635 1.22e-66 229.0 COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,2VHJV@28216|Betaproteobacteria,1K10V@119060|Burkholderiaceae 28216|Betaproteobacteria D Belongs to the FtsK SpoIIIE SftA family ftsK - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma k141_29562_1 218284.CCDN010000007_gene3822 3.2e-135 392.0 COG0754@1|root,COG0754@2|Bacteria,1UTUT@1239|Firmicutes,4HBAJ@91061|Bacilli,1ZB3R@1386|Bacillus 91061|Bacilli E Glutathionylspermidine synthase preATP-grasp - - - - - - - - - - - - GSP_synth k141_34314_2 314285.KT71_05502 6.54e-198 566.0 COG4145@1|root,COG4145@2|Bacteria,1QYUD@1224|Proteobacteria,1RZPW@1236|Gammaproteobacteria,1J8XU@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - - - - - - - - - - SSF k141_17573_2 218284.CCDN010000001_gene1132 2.46e-35 126.0 COG0289@1|root,COG0289@2|Bacteria,1TR9D@1239|Firmicutes,4HA5X@91061|Bacilli,1ZAWD@1386|Bacillus 91061|Bacilli E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate dapB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R04198,R04199 RC00478 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU22490 DapB_C,DapB_N k141_20150_2 218284.CCDN010000004_gene3054 1.21e-22 94.0 COG1176@1|root,COG1176@2|Bacteria,1V1K7@1239|Firmicutes,4HG7A@91061|Bacilli,1ZGHA@1386|Bacillus 91061|Bacilli E transport system, permease component - - - ko:K02054 ko02024,map02024 M00193 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11 - - BPD_transp_1 k141_3316_1 218284.CCDN010000002_gene2205 3.38e-101 300.0 COG5662@1|root,COG5662@2|Bacteria,1V446@1239|Firmicutes,4HHFJ@91061|Bacilli,1ZHD5@1386|Bacillus 91061|Bacilli K Anti-sigma-K factor rskA - - - - - - - - - - - - RskA,zf-HC2 k141_37722_1 218284.CCDN010000008_gene4143 1.43e-97 300.0 COG1165@1|root,COG1165@2|Bacteria,1TRDB@1239|Firmicutes,4HC48@91061|Bacilli,1ZANU@1386|Bacillus 91061|Bacilli H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) menD - 2.2.1.9 ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R08165 RC02186 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS05085 TPP_enzyme_C,TPP_enzyme_M_2,TPP_enzyme_N k141_7959_1 1078085.HMPREF1210_00664 4.48e-61 213.0 COG1404@1|root,COG1404@2|Bacteria,1TPH1@1239|Firmicutes,4HBQH@91061|Bacilli,26DQR@186818|Planococcaceae 91061|Bacilli M Belongs to the peptidase S8 family - - - - - - - - - - - - Inhibitor_I9,PA,Peptidase_S8,SLH,fn3_5 k141_34315_1 1042377.AFPJ01000008_gene1964 9.99e-100 312.0 COG1472@1|root,COG1472@2|Bacteria,1MVIV@1224|Proteobacteria,1RMA0@1236|Gammaproteobacteria,465BV@72275|Alteromonadaceae 1236|Gammaproteobacteria G Family 3 - - 3.2.1.21 ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 - R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - GH3 - CBM_6,Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C k141_29563_1 218284.CCDN010000001_gene727 1.27e-53 177.0 COG0680@1|root,COG0680@2|Bacteria,1TPFY@1239|Firmicutes,4HAGH@91061|Bacilli,1ZC4A@1386|Bacillus 91061|Bacilli C Initiates the rapid degradation of small, acid-soluble proteins during spore germination gpr GO:0000003,GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019954,GO:0030436,GO:0032502,GO:0043170,GO:0043934,GO:0044238,GO:0071704,GO:0140096,GO:1901564 3.4.24.78 ko:K06012 - - - - ko00000,ko01000,ko01002 - - - Peptidase_A25 k141_29563_2 218284.CCDN010000001_gene726 1.84e-43 142.0 COG0268@1|root,COG0268@2|Bacteria,1VEGX@1239|Firmicutes,4HNJS@91061|Bacilli,1ZI3X@1386|Bacillus 91061|Bacilli J Binds directly to 16S ribosomal RNA rpsT - - ko:K02968 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S20p k141_20151_1 218284.CCDN010000001_gene1839 1.74e-120 351.0 COG0381@1|root,COG0381@2|Bacteria,1TQZT@1239|Firmicutes,4HBQ7@91061|Bacilli,1ZBD7@1386|Bacillus 91061|Bacilli M Belongs to the UDP-N-acetylglucosamine 2-epimerase family capG - 5.1.3.14 ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 M00362 R00420 RC00290 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Epimerase_2 k141_10547_1 218284.CCDN010000002_gene2402 2.4e-236 666.0 COG0376@1|root,COG0376@2|Bacteria,1TQDA@1239|Firmicutes,4HBZ5@91061|Bacilli,1ZD07@1386|Bacillus 91061|Bacilli P Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity katG - 1.11.1.21 ko:K03782 ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110 - R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906 RC00034,RC00213,RC00767,RC02141 ko00000,ko00001,ko01000 - - - peroxidase k141_2080_2 1279017.AQYJ01000028_gene2507 1.63e-310 850.0 COG0189@1|root,COG4067@1|root,COG0189@2|Bacteria,COG4067@2|Bacteria,1MX62@1224|Proteobacteria,1RM8B@1236|Gammaproteobacteria,469U8@72275|Alteromonadaceae 1236|Gammaproteobacteria HJO Putative ATP-dependant zinc protease rimK - - ko:K05844 - - - - ko00000,ko01000,ko03009 - - - RimK,Zn_protease k141_17574_2 1279017.AQYJ01000019_gene1460 5.43e-120 343.0 COG0094@1|root,COG0094@2|Bacteria,1MUU9@1224|Proteobacteria,1RPE1@1236|Gammaproteobacteria,464A7@72275|Alteromonadaceae 1236|Gammaproteobacteria J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits rplE GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02931 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L5,Ribosomal_L5_C k141_33044_1 218284.CCDN010000005_gene3404 2.57e-265 734.0 COG1757@1|root,COG1757@2|Bacteria,1TP8A@1239|Firmicutes,4HB2I@91061|Bacilli,1ZCTW@1386|Bacillus 91061|Bacilli C Na+/H+ antiporter family nhaC2 - - - - - - - - - - - Na_H_antiporter k141_1174_1 1042377.AFPJ01000028_gene2216 2.01e-195 548.0 COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,1RRTP@1236|Gammaproteobacteria,464NN@72275|Alteromonadaceae 1236|Gammaproteobacteria T GGDEF domain - GO:0003674,GO:0003824,GO:0005488,GO:0008144,GO:0016740,GO:0016772,GO:0016779,GO:0019825,GO:0020037,GO:0036094,GO:0042165,GO:0043167,GO:0043169,GO:0046906,GO:0048037,GO:0052621,GO:0070025,GO:0097159,GO:1901363 2.7.7.65 ko:K13069 - - R08057 - ko00000,ko01000 - - - GGDEF k141_24859_1 1348635.BBJY01000003_gene3774 7.57e-69 223.0 28H6M@1|root,2Z7J0@2|Bacteria,1R7G5@1224|Proteobacteria,1RPZU@1236|Gammaproteobacteria,1XWJ4@135623|Vibrionales 135623|Vibrionales G Periplasmic pectate lyase - - 4.2.2.9 ko:K01731 ko00040,map00040 - R02361,R06240 RC00049,RC00705 ko00000,ko00001,ko01000 - - - Pectate_lyase_2 k141_24859_2 1348635.BBJY01000003_gene3775 2.8e-179 507.0 COG1653@1|root,COG1653@2|Bacteria,1MVGS@1224|Proteobacteria,1RQFU@1236|Gammaproteobacteria,1XUX4@135623|Vibrionales 135623|Vibrionales G Bacterial extracellular solute-binding protein - - - - - - - - - - - - SBP_bac_8 k141_7960_1 1380354.JIAN01000005_gene2543 8.74e-37 141.0 COG0303@1|root,COG0303@2|Bacteria,2GJC3@201174|Actinobacteria,4F15H@85016|Cellulomonadaceae 201174|Actinobacteria H PFAM MoeA domain protein domain I and II - - 2.10.1.1 ko:K03750 ko00790,ko01100,map00790,map01100 - R09735 RC03462 ko00000,ko00001,ko01000 - - - MoCF_biosynth,MoeA_C,MoeA_N k141_24860_1 218284.CCDN010000001_gene1580 2.86e-142 430.0 COG0454@1|root,COG0456@2|Bacteria,1TQQA@1239|Firmicutes,4HBXN@91061|Bacilli,1ZEEE@1386|Bacillus 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10 k141_7961_1 1294265.JCM21738_3410 1.26e-93 284.0 COG0750@1|root,COG0750@2|Bacteria,1TPIR@1239|Firmicutes,4H9TW@91061|Bacilli,1ZB04@1386|Bacillus 91061|Bacilli M Stage IV sporulation protein B spoIVB - 3.4.21.116 ko:K06399 - - - - ko00000,ko01000,ko01002 - - - PDZ,PDZ_2,Peptidase_S55 k141_5921_1 1042377.AFPJ01000028_gene2210 0.0 946.0 COG0834@1|root,COG4623@1|root,COG0834@2|Bacteria,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,1RM8W@1236|Gammaproteobacteria,467JF@72275|Alteromonadaceae 1236|Gammaproteobacteria EMT Bacterial periplasmic substrate-binding proteins - GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - ko:K18691 - - - - ko00000,ko01000,ko01011 - - - SBP_bac_3,SLT k141_5921_2 1042377.AFPJ01000035_gene2621 2.21e-211 591.0 COG5434@1|root,COG5434@2|Bacteria,1MUGF@1224|Proteobacteria,1RS20@1236|Gammaproteobacteria,46AM6@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the glycosyl hydrolase 28 family - - - - - - - - - - - - Beta_helix k141_5921_3 1042377.AFPJ01000035_gene2622 3.11e-246 684.0 COG3420@1|root,COG3420@2|Bacteria,1QUPB@1224|Proteobacteria,1T2I7@1236|Gammaproteobacteria,46D8Q@72275|Alteromonadaceae 1236|Gammaproteobacteria P Periplasmic copper-binding protein (NosD) - - - - - - - - - - - - Beta_helix,NosD k141_5921_5 1279017.AQYJ01000022_gene2620 4.05e-113 327.0 28H8Z@1|root,2Z7KS@2|Bacteria,1MW9T@1224|Proteobacteria,1RQV1@1236|Gammaproteobacteria,465P3@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF1282) - - - - - - - - - - - - DUF1282 k141_33045_1 218284.CCDN010000001_gene988 2.74e-143 445.0 COG1404@1|root,COG4412@1|root,COG1404@2|Bacteria,COG4412@2|Bacteria,1TPUY@1239|Firmicutes,4HBDE@91061|Bacilli,1ZDEQ@1386|Bacillus 91061|Bacilli O COG1404 Subtilisin-like serine proteases bpr GO:0005575,GO:0005576 - ko:K13276 - - - - ko00000,ko01000,ko01002,ko03110 - - - CarbopepD_reg_2,CarboxypepD_reg,Inhibitor_I9,Peptidase_M6,Peptidase_S8 k141_29568_1 218284.CCDN010000001_gene1467 4.5e-101 298.0 COG1028@1|root,COG1028@2|Bacteria,1TS0K@1239|Firmicutes,4HA78@91061|Bacilli,1ZESQ@1386|Bacillus 91061|Bacilli IQ Enoyl-(Acyl carrier protein) reductase - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 k141_34318_1 1122194.AUHU01000003_gene2119 8.54e-74 247.0 COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,1RNIF@1236|Gammaproteobacteria,465NJ@72275|Alteromonadaceae 1236|Gammaproteobacteria P Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family cecA_2 - - ko:K07239 - - - - ko00000 2.A.6.1 - - ACR_tran k141_35632_1 1116375.VEJY3_07585 0.0 1392.0 COG0116@1|root,COG1092@1|root,COG0116@2|Bacteria,COG1092@2|Bacteria,1MUQM@1224|Proteobacteria,1RNMH@1236|Gammaproteobacteria,1XSNR@135623|Vibrionales 135623|Vibrionales J Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA rlmL GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.173,2.1.1.264 ko:K12297 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - Methyltrans_SAM,THUMP,UPF0020 k141_21127_1 1423321.AS29_03430 5.58e-10 59.7 COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,4H9SB@91061|Bacilli,1ZBAN@1386|Bacillus 91061|Bacilli S COG1253 Hemolysins and related proteins containing CBS domains yrkA - - - - - - - - - - - CBS,CorC_HlyC,DUF21 k141_21127_2 265729.GS18_0217685 4.53e-33 126.0 COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,4H9SR@91061|Bacilli,1ZCDX@1386|Bacillus 91061|Bacilli S transporter activity yueF GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - - - - - - - - - - AI-2E_transport k141_3342_1 218284.CCDN010000005_gene3405 1.75e-175 500.0 COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,4HAAI@91061|Bacilli,1ZBC5@1386|Bacillus 91061|Bacilli S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family - - - ko:K03308 - - - - ko00000 2.A.22.4,2.A.22.5 - - SNF k141_32010_2 1453501.JELR01000001_gene2645 1.12e-127 371.0 COG0300@1|root,COG0300@2|Bacteria,1NH6F@1224|Proteobacteria,1S0XK@1236|Gammaproteobacteria,46ACT@72275|Alteromonadaceae 1236|Gammaproteobacteria S KR domain - - - - - - - - - - - - adh_short k141_32010_3 1279017.AQYJ01000025_gene497 1.1e-31 120.0 COG0451@1|root,COG0451@2|Bacteria,1N8PG@1224|Proteobacteria,1RWCX@1236|Gammaproteobacteria,469BZ@72275|Alteromonadaceae 1236|Gammaproteobacteria GM NAD-dependent epimerase dehydratase - - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase k141_30845_1 1294265.JCM21738_5465 3.19e-113 332.0 COG2199@1|root,COG3706@2|Bacteria,1TXUE@1239|Firmicutes,4H9X2@91061|Bacilli,1ZD75@1386|Bacillus 91061|Bacilli T diguanylate cyclase - - - - - - - - - - - - GGDEF k141_30846_2 1123518.ARWI01000001_gene854 5.93e-11 59.3 COG2827@1|root,COG2827@2|Bacteria,1MZME@1224|Proteobacteria,1S8Z1@1236|Gammaproteobacteria,462MC@72273|Thiotrichales 72273|Thiotrichales L GIY-YIG catalytic domain - - - ko:K07461 - - - - ko00000 - - - GIY-YIG k141_30848_1 665959.HMPREF1013_02811 1.02e-54 176.0 29RS5@1|root,30CVW@2|Bacteria,1UAG1@1239|Firmicutes,4IKUE@91061|Bacilli,1ZHMI@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_32011_1 1042377.AFPJ01000034_gene2316 1.38e-213 596.0 COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,1RMVY@1236|Gammaproteobacteria,465WX@72275|Alteromonadaceae 1236|Gammaproteobacteria G Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions pfp - 2.7.1.11,2.7.1.90 ko:K21071 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 - R00756,R00764,R02073,R03236,R04779 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PFK k141_30849_3 1279017.AQYJ01000023_gene3107 2.8e-112 331.0 COG1091@1|root,COG1091@2|Bacteria,1MUXM@1224|Proteobacteria,1RSNR@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose - - 1.1.1.133 ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777 RC00182 ko00000,ko00001,ko00002,ko01000 - - - RmlD_sub_bind k141_30850_1 395963.Bind_1176 8.26e-26 101.0 COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,2TUP5@28211|Alphaproteobacteria,3NACR@45404|Beijerinckiaceae 28211|Alphaproteobacteria L Methyladenine glycosylase tag - 3.2.2.20 ko:K01246 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Adenine_glyco k141_14278_4 1116375.VEJY3_13650 1.58e-111 323.0 COG2854@1|root,COG2854@2|Bacteria,1NKFA@1224|Proteobacteria,1RNJW@1236|Gammaproteobacteria,1XT3S@135623|Vibrionales 135623|Vibrionales Q ABC-type transport system involved in resistance to organic solvents, auxiliary component mlaC - - ko:K07323 ko02010,map02010 M00210 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27.3 - - MlaC k141_4773_1 315750.BPUM_2900 1.88e-44 146.0 COG3377@1|root,COG3377@2|Bacteria,1VAP7@1239|Firmicutes,4HKBM@91061|Bacilli,1ZHYB@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF1805) yunC - - - - - - - - - - - DUF1805 k141_19034_1 1132442.KB889752_gene2152 6.45e-70 220.0 COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,4HABP@91061|Bacilli,1ZBKZ@1386|Bacillus 91061|Bacilli F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate punA - 2.4.2.1,2.4.2.28 ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 M00034 R01402,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244 RC00033,RC00063,RC00122,RC02819 ko00000,ko00001,ko00002,ko01000 - - - PNP_UDP_1 k141_22599_1 1116375.VEJY3_14275 7.74e-190 536.0 COG1012@1|root,COG1012@2|Bacteria,1MV2I@1224|Proteobacteria,1RPQW@1236|Gammaproteobacteria,1XTD0@135623|Vibrionales 135623|Vibrionales C Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate astD GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.2.1.71 ko:K06447 ko00330,ko01100,map00330,map01100 - R05049 RC00080 ko00000,ko00001,ko01000 - - - Aldedh k141_22599_2 1116375.VEJY3_14270 3.41e-185 515.0 COG5383@1|root,COG5383@2|Bacteria,1MWTV@1224|Proteobacteria,1RNJF@1236|Gammaproteobacteria,1XTHF@135623|Vibrionales 135623|Vibrionales S DUF1338 - - - - - - - - - - - - DUF1338 k141_22599_3 55601.VANGNB10_cI2365 8.78e-148 416.0 COG0664@1|root,COG0664@2|Bacteria,1MXID@1224|Proteobacteria,1RMIZ@1236|Gammaproteobacteria,1XT4N@135623|Vibrionales 135623|Vibrionales K COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases crp - - ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 - - - ko00000,ko00001,ko03000 - - - Crp,cNMP_binding k141_22599_4 1280001.BAOA01000039_gene2505 3.63e-92 275.0 COG3954@1|root,COG3954@2|Bacteria,1MWN9@1224|Proteobacteria,1RMS7@1236|Gammaproteobacteria,1XSST@135623|Vibrionales 135623|Vibrionales G Phosphoribulokinase prkB - 2.7.1.19 ko:K00855 ko00710,ko01100,ko01120,ko01200,map00710,map01100,map01120,map01200 M00165,M00166 R01523 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - PRK k141_21422_1 1042377.AFPJ01000036_gene1268 5.12e-36 131.0 COG0300@1|root,COG0300@2|Bacteria,1NH6F@1224|Proteobacteria,1S0XK@1236|Gammaproteobacteria,46ACT@72275|Alteromonadaceae 1236|Gammaproteobacteria S KR domain - - - - - - - - - - - - adh_short k141_8345_2 1279017.AQYJ01000023_gene3085 8.71e-15 73.6 COG0471@1|root,COG0569@1|root,COG0471@2|Bacteria,COG0569@2|Bacteria,1MU0K@1224|Proteobacteria,1RMI1@1236|Gammaproteobacteria,464A6@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0471 Di- and tricarboxylate transporters - - - - - - - - - - - - CitMHS,TrkA_C k141_4774_1 1042377.AFPJ01000020_gene2059 1.47e-79 258.0 COG0457@1|root,COG0457@2|Bacteria,1MX2U@1224|Proteobacteria,1RPD2@1236|Gammaproteobacteria,464NG@72275|Alteromonadaceae 1236|Gammaproteobacteria C Cytochrome c554 and c-prime - - - - - - - - - - - - Cytochrome_C554,HEAT_2,Paired_CXXCH_1,TPR_16,TPR_19,TPR_20,TPR_8 k141_28550_1 1123228.AUIH01000014_gene348 2.35e-172 493.0 COG0477@1|root,COG2814@2|Bacteria,1MW19@1224|Proteobacteria,1RMSZ@1236|Gammaproteobacteria,1XMXT@135619|Oceanospirillales 135619|Oceanospirillales EGP Sugar (and other) transporter - - - ko:K07552 - - - - ko00000,ko02000 2.A.1.2 - - MFS_1 k141_20_1 1294265.JCM21738_3983 3.39e-18 77.0 COG2427@1|root,COG2427@2|Bacteria,1W22B@1239|Firmicutes,4I0T7@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF1641) - - - - - - - - - - - - - k141_20_2 1294265.JCM21738_3984 2.34e-101 302.0 COG0446@1|root,COG0446@2|Bacteria,1UC47@1239|Firmicutes,4HDIM@91061|Bacilli,1ZDDQ@1386|Bacillus 91061|Bacilli S Pyridine nucleotide-disulphide oxidoreductase - - 1.8.5.4 ko:K17218 ko00920,map00920 - R10152 RC03155 ko00000,ko00001,ko01000 - - - Pyr_redox_2 k141_11900_1 366602.Caul_2355 0.000305 44.7 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,2TS4W@28211|Alphaproteobacteria,2KFP2@204458|Caulobacterales 204458|Caulobacterales P TonB-dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec k141_5961_1 218284.CCDN010000001_gene165 5.99e-27 108.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,1ZASV@1386|Bacillus 91061|Bacilli V COG1132 ABC-type multidrug transport system, ATPase and permease components yknU GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702 - ko:K06147,ko:K11085 ko02010,map02010 - - - ko00000,ko00001,ko01000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran k141_5961_2 218284.CCDN010000001_gene164 3.04e-140 412.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,1ZBIW@1386|Bacillus 91061|Bacilli V COG1132 ABC-type multidrug transport system, ATPase and permease components yknV GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702 - ko:K02021,ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21 - - ABC_membrane,ABC_tran k141_15472_1 42565.FP66_10360 8.75e-39 142.0 COG0247@1|root,COG0247@2|Bacteria,1MUMH@1224|Proteobacteria,1RNBY@1236|Gammaproteobacteria,1XHJ2@135619|Oceanospirillales 135619|Oceanospirillales C Domain of unknown function (DUF3483) - - - ko:K21834 - - - - ko00000 - - - CCG,DUF3483,Fer4_8 k141_15472_2 42565.FP66_10355 5.39e-38 140.0 COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,1RNM8@1236|Gammaproteobacteria,1XH4X@135619|Oceanospirillales 135619|Oceanospirillales C NADH flavin oxidoreductase NADH oxidase - - - ko:K21833 - - - - ko00000 - - - Oxidored_FMN,Pyr_redox_2 k141_33302_1 1294265.JCM21738_2108 8.69e-87 259.0 COG0745@1|root,COG0745@2|Bacteria,1UX1V@1239|Firmicutes,4HD2J@91061|Bacilli,1ZDIX@1386|Bacillus 91061|Bacilli T Transcriptional regulatory protein, C terminal - - - - - - - - - - - - Response_reg,Trans_reg_C k141_21423_1 218284.CCDN010000001_gene1787 6.14e-112 330.0 COG4851@1|root,COG4851@2|Bacteria,1U8WG@1239|Firmicutes,4IIV0@91061|Bacilli,1ZMRB@1386|Bacillus 91061|Bacilli S CamS sex pheromone cAM373 precursor - - - - - - - - - - - - CamS k141_8346_1 935836.JAEL01000061_gene3707 1.09e-26 108.0 COG4477@1|root,COG4477@2|Bacteria,1TQR7@1239|Firmicutes,4HA15@91061|Bacilli,1ZAWX@1386|Bacillus 91061|Bacilli D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization ezrA GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000918,GO:0000921,GO:0005575,GO:0005623,GO:0005886,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0022402,GO:0022607,GO:0031106,GO:0032185,GO:0032506,GO:0034622,GO:0043933,GO:0044085,GO:0044464,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051301,GO:0051302,GO:0051781,GO:0061640,GO:0065003,GO:0065007,GO:0070925,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 - ko:K06286 - - - - ko00000,ko03036 - - - EzrA k141_8346_2 1294265.JCM21738_4485 6.04e-44 150.0 COG1387@1|root,COG1387@2|Bacteria,1TQQX@1239|Firmicutes,4H9P1@91061|Bacilli,1ZCA3@1386|Bacillus 91061|Bacilli E COG1387 Histidinol phosphatase and related hydrolases of the PHP family hisK GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.15 ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R03013 RC00017 ko00000,ko00001,ko00002,ko01000 - - - PHP,PHP_C k141_28551_1 1294265.JCM21738_1887 1.62e-94 284.0 COG2358@1|root,COG2358@2|Bacteria,1TPXW@1239|Firmicutes,4HB7U@91061|Bacilli,1ZEBW@1386|Bacillus 91061|Bacilli S NMT1-like family - - - ko:K07080 - - - - ko00000 - - - NMT1_3 k141_36865_1 1453501.JELR01000002_gene978 2.1e-56 187.0 COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,1RN6I@1236|Gammaproteobacteria,4654G@72275|Alteromonadaceae 1236|Gammaproteobacteria H Involved in the biosynthesis of porphyrin-containing compound yggW GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - - - - - - - - - - HemN_C,Radical_SAM k141_36865_2 1042377.AFPJ01000054_gene1722 4.52e-17 77.8 COG0127@1|root,COG0127@2|Bacteria,1MUK5@1224|Proteobacteria,1S27C@1236|Gammaproteobacteria,466HT@72275|Alteromonadaceae 1236|Gammaproteobacteria F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions rdgB GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035870,GO:0036220,GO:0036222,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0046983,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 ko:K02428 ko00230,map00230 - R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000 - - iEC55989_1330.EC55989_3247,iECO111_1330.ECO111_3702,iECSE_1348.ECSE_3222,iECW_1372.ECW_m3212,iEKO11_1354.EKO11_0774,iEcE24377_1341.EcE24377A_3298,iWFL_1372.ECW_m3212 Ham1p_like k141_2395_1 218284.CCDN010000004_gene3101 3.27e-114 341.0 COG0471@1|root,COG0471@2|Bacteria,1TSP2@1239|Firmicutes,4H9UV@91061|Bacilli,1ZARD@1386|Bacillus 91061|Bacilli P Sodium:sulfate symporter transmembrane region sdcS - - ko:K14445 - - - - ko00000,ko02000 2.A.47.1 - - Na_sulph_symp k141_34492_1 1453501.JELR01000001_gene3049 1.92e-97 296.0 COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,1RMGD@1236|Gammaproteobacteria,464UU@72275|Alteromonadaceae 1236|Gammaproteobacteria M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein murF GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008766,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0047480,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 - R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - iB21_1397.B21_00086,iEC042_1314.EC042_0087,iEC55989_1330.EC55989_0082,iECBD_1354.ECBD_3531,iECB_1328.ECB_00087,iECD_1391.ECD_00087,iECIAI1_1343.ECIAI1_0085,iECO103_1326.ECO103_0088,iECO111_1330.ECO111_0089,iECO26_1355.ECO26_0089,iECSE_1348.ECSE_0088,iECW_1372.ECW_m0085,iEKO11_1354.EKO11_3828,iEcE24377_1341.EcE24377A_0088,iEcHS_1320.EcHS_A0092,iEcolC_1368.EcolC_3571,iSBO_1134.SBO_0074,iSSON_1240.SSON_0094,iSbBS512_1146.SbBS512_E0079,iUMNK88_1353.UMNK88_86,iWFL_1372.ECW_m0085,iYL1228.KPN_00090 Mur_ligase,Mur_ligase_C,Mur_ligase_M k141_22600_1 391616.OA238_c19220 1.79e-07 58.2 COG0569@1|root,COG0569@2|Bacteria,1MW8R@1224|Proteobacteria,2TRP9@28211|Alphaproteobacteria 28211|Alphaproteobacteria P COG0569 K transport systems, NAD-binding component trkA - - ko:K03499 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkA_C,TrkA_N k141_16652_1 1453501.JELR01000002_gene430 3.09e-245 684.0 COG4264@1|root,COG4264@2|Bacteria,1QUJJ@1224|Proteobacteria,1RQQ0@1236|Gammaproteobacteria,46A5Y@72275|Alteromonadaceae 1236|Gammaproteobacteria Q IucA / IucC family iucA - - - - - - - - - - - FhuF,IucA_IucC k141_3588_1 218284.CCDN010000001_gene1019 1.44e-174 494.0 COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,4HA1P@91061|Bacilli,1ZC8I@1386|Bacillus 91061|Bacilli L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII dinB2 - - ko:K03502 - - - - ko00000,ko03400 - - - IMS,IMS_C,IMS_HHH k141_5963_1 218284.CCDN010000001_gene141 7.42e-54 170.0 2E309@1|root,32Y0U@2|Bacteria,1VEZC@1239|Firmicutes,4HNYA@91061|Bacilli,1ZQK1@1386|Bacillus 91061|Bacilli S YlaH-like protein - - - - - - - - - - - - YlaH k141_8347_1 518766.Rmar_1285 1.67e-86 266.0 COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,1FJ1G@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes S ATPase family associated with various cellular activities (AAA) moxR - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 k141_7145_2 1385511.N783_13095 5.43e-85 258.0 COG2323@1|root,COG2323@2|Bacteria,1V1AI@1239|Firmicutes,4HDBF@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF421) - - - - - - - - - - - - DUF421 k141_7145_3 1131730.BAVI_21853 3.54e-64 206.0 COG0492@1|root,COG0492@2|Bacteria,1TRPN@1239|Firmicutes,4HACJ@91061|Bacilli,1ZB05@1386|Bacillus 91061|Bacilli C Ferredoxin--NADP reductase - - 1.18.1.2,1.19.1.1 ko:K21567 - - - - ko00000,ko01000 - - - Pyr_redox_2,Pyr_redox_3 k141_19035_1 1279017.AQYJ01000027_gene1812 2.91e-24 95.1 COG3312@1|root,COG3312@2|Bacteria,1N777@1224|Proteobacteria,1SD0Z@1236|Gammaproteobacteria,468Z4@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG3312 F0F1-type ATP synthase, subunit I atpI GO:0003674,GO:0003824,GO:0005215,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044769,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02116 - - - - ko00000,ko00194 3.A.2.1 - - ATP-synt_I k141_1198_1 1294265.JCM21738_4362 5.56e-89 273.0 COG1207@1|root,COG1207@2|Bacteria,1TP88@1239|Firmicutes,4H9V5@91061|Bacilli,1ZAVH@1386|Bacillus 91061|Bacilli M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain glmU GO:0000270,GO:0000271,GO:0003674,GO:0003824,GO:0003977,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006629,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0030203,GO:0033692,GO:0034637,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509 2.3.1.157,2.7.7.23 ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00362 R00416,R05332 RC00002,RC00004,RC00166 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transf_3,NTP_transferase k141_21_1 218284.CCDN010000001_gene1923 2.76e-56 186.0 COG1749@1|root,COG1749@2|Bacteria,1UHS7@1239|Firmicutes,4IS7Y@91061|Bacilli,1ZS24@1386|Bacillus 91061|Bacilli N flagellar flgE - - ko:K02390 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FlaE,Flg_bb_rod,Flg_bbr_C k141_21_2 997296.PB1_01070 3.47e-23 90.5 COG1582@1|root,COG1582@2|Bacteria,1VKHB@1239|Firmicutes,4HP2W@91061|Bacilli,1ZIYN@1386|Bacillus 91061|Bacilli N protein, possibly involved in motility flbD - - ko:K02385 - - - - ko00000,ko02035 - - - FlbD k141_13093_2 223926.28809058 2.21e-301 828.0 COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,1RYKM@1236|Gammaproteobacteria,1XW1Q@135623|Vibrionales 135623|Vibrionales G Belongs to the pyruvate kinase family - - 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - PK,PK_C k141_13093_3 223926.28809059 0.0 872.0 COG2271@1|root,COG2271@2|Bacteria,1MX4V@1224|Proteobacteria,1RMB3@1236|Gammaproteobacteria,1XSIZ@135623|Vibrionales 135623|Vibrionales G COG2271 Sugar phosphate permease - - - ko:K07783 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.1.4.4,2.A.1.4.6 - - MFS_1 k141_13093_4 223926.28809060 9.53e-243 675.0 COG1840@1|root,COG1840@2|Bacteria,1MWWI@1224|Proteobacteria,1RRWU@1236|Gammaproteobacteria,1XVQZ@135623|Vibrionales 135623|Vibrionales P Phosphoglycerate transport regulatory protein PGTC VPA0825 - - ko:K08478 ko02020,map02020 - - - ko00000,ko00001 - - - SBP_bac_6 k141_13093_5 223926.28809061 2.35e-47 168.0 COG4191@1|root,COG4192@1|root,COG4191@2|Bacteria,COG4192@2|Bacteria,1RCM9@1224|Proteobacteria,1RQIN@1236|Gammaproteobacteria,1XTW1@135623|Vibrionales 135623|Vibrionales T COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system - - 2.7.13.3 ko:K08475 ko02020,map02020 M00503 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - 4HB_MCP_1,HATPase_c,HisKA,PAS_9 k141_28553_1 1385511.N783_09410 1.96e-20 90.9 COG0577@1|root,COG0577@2|Bacteria,1TPHU@1239|Firmicutes,4HA2C@91061|Bacilli,2Y8N0@289201|Pontibacillus 91061|Bacilli V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX k141_28553_2 1385512.N784_03035 2.04e-64 202.0 COG1136@1|root,COG1136@2|Bacteria,1TQC9@1239|Firmicutes,4HB8D@91061|Bacilli,2Y8P5@289201|Pontibacillus 91061|Bacilli V ABC transporter ATP-binding protein - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_30921_2 1042377.AFPJ01000020_gene2040 0.0 958.0 COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,465WS@72275|Alteromonadaceae 1236|Gammaproteobacteria E Gamma-glutamyltranspeptidase ggt_2 - 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept k141_30921_3 1279017.AQYJ01000021_gene2877 0.0 1282.0 COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,1RMA7@1236|Gammaproteobacteria,465DP@72275|Alteromonadaceae 1236|Gammaproteobacteria E aminopeptidase N pepN GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0009056,GO:0009987,GO:0016020,GO:0016787,GO:0019538,GO:0033218,GO:0034641,GO:0042277,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - iECIAI1_1343.ECIAI1_0973,iECO103_1326.ECO103_0977,iECP_1309.ECP_0944,iECSE_1348.ECSE_0993,iECW_1372.ECW_m1042,iEKO11_1354.EKO11_2898,iWFL_1372.ECW_m1042 DUF3458,DUF3458_C,Peptidase_M1 k141_30921_4 1333998.M2A_1085 2.13e-26 106.0 COG0406@1|root,COG0406@2|Bacteria,1MYD7@1224|Proteobacteria,2TVST@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Phosphoglycerate mutase family - - - - - - - - - - - - His_Phos_1 k141_4777_1 218284.CCDN010000002_gene2135 7.49e-110 338.0 COG0210@1|root,COG0210@2|Bacteria,1TPVG@1239|Firmicutes,4HBVF@91061|Bacilli,1ZCF6@1386|Bacillus 91061|Bacilli L DNA helicase yjcD - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C,YdjO k141_34493_1 218284.CCDN010000006_gene3594 1.82e-171 495.0 COG0843@1|root,COG0843@2|Bacteria,1TP2U@1239|Firmicutes,4HA4X@91061|Bacilli,1ZBD5@1386|Bacillus 91061|Bacilli C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B qoxB GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009486,GO:0009987,GO:0015002,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016310,GO:0016491,GO:0016679,GO:0016682,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0034220,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0098655,GO:0098660,GO:0098662,GO:1901135,GO:1901360,GO:1901564,GO:1902600 1.10.3.12 ko:K02827 ko00190,ko01100,map00190,map01100 M00416 R09492 RC00819 ko00000,ko00001,ko00002,ko01000 3.D.4.1 - - COX1 k141_15475_1 1385512.N784_12305 1.73e-19 89.7 COG0760@1|root,COG0760@2|Bacteria,1V831@1239|Firmicutes,4HGCD@91061|Bacilli,2YAPH@289201|Pontibacillus 91061|Bacilli O SurA N-terminal domain - - - - - - - - - - - - SurA_N_3 k141_35679_2 566466.NOR53_517 6.24e-34 125.0 COG2067@1|root,COG2067@2|Bacteria 2|Bacteria I long-chain fatty acid transporting porin activity - - - ko:K06076 - - - - ko00000,ko02000 1.B.9 - - Phenol_MetA_deg,Toluene_X k141_8348_1 1122927.KB895427_gene2222 6.02e-79 243.0 COG0561@1|root,COG0561@2|Bacteria,1TQTU@1239|Firmicutes,4HDUC@91061|Bacilli,26T85@186822|Paenibacillaceae 91061|Bacilli S haloacid dehalogenase-like hydrolase - - - - - - - - - - - - Hydrolase_3 k141_19036_1 714961.BFZC1_16380 1.56e-16 77.8 COG2514@1|root,COG2514@2|Bacteria,1TPRF@1239|Firmicutes,4HAE7@91061|Bacilli,3IWSS@400634|Lysinibacillus 91061|Bacilli S Glyoxalase catE - 1.13.11.2 ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 M00569 R00816,R04089,R05295,R05404,R05406,R07795 RC00387,RC00643,RC01075,RC01364,RC01914 ko00000,ko00001,ko00002,ko01000 - - - Glyoxalase k141_10710_1 1453501.JELR01000001_gene2508 3.48e-204 590.0 28IUR@1|root,2Z8TE@2|Bacteria,1NW7C@1224|Proteobacteria,1RP4W@1236|Gammaproteobacteria,465G0@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_1199_1 1294265.JCM21738_2193 7.47e-119 343.0 COG3971@1|root,COG3971@2|Bacteria,1UYC8@1239|Firmicutes,4HB58@91061|Bacilli,1ZDRH@1386|Bacillus 91061|Bacilli Q COG3971 2-keto-4-pentenoate hydratase - - 4.1.1.77 ko:K01617 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 M00569 R02602,R05374 RC00751,RC02672 ko00000,ko00001,ko00002,ko01000 - - - FAA_hydrolase k141_2396_2 1219080.VEZ01S_17_00030 2.26e-55 184.0 COG2378@1|root,COG2378@2|Bacteria,1QMYB@1224|Proteobacteria,1TH80@1236|Gammaproteobacteria,1XSAV@135623|Vibrionales 135623|Vibrionales K WYL domain - - - - - - - - - - - - WYL k141_35680_1 400668.Mmwyl1_3146 1.9e-107 322.0 28H52@1|root,2Z7HQ@2|Bacteria,1MXTF@1224|Proteobacteria,1RN8H@1236|Gammaproteobacteria,1XHP8@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF1329) - - - - - - - - - - - - DUF1329 k141_11901_1 218284.CCDN010000006_gene3519 1.12e-107 316.0 COG0506@1|root,COG0506@2|Bacteria,1TQV3@1239|Firmicutes,4HAC1@91061|Bacilli,1ZB5G@1386|Bacillus 91061|Bacilli E Proline dehydrogenase fadM GO:0000166,GO:0003674,GO:0003824,GO:0004657,GO:0005488,GO:0006082,GO:0006520,GO:0006560,GO:0006562,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016491,GO:0016645,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 - ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 - R10507 RC00083 ko00000,ko00001,ko01000 - - - Pro_dh k141_11901_2 218284.CCDN010000006_gene3517 4.28e-75 238.0 COG3263@1|root,COG3263@2|Bacteria,1TQPJ@1239|Firmicutes,4HC8I@91061|Bacilli,1ZC6H@1386|Bacillus 91061|Bacilli P COG3263 NhaP-type Na H and K H antiporters with a unique C-terminal domain cvrA - - ko:K11105 - - - - ko00000,ko02000 2.A.36.6 - - Na_H_Exchanger,TrkA_C k141_19037_2 1117647.M5M_07320 2.16e-25 101.0 COG3148@1|root,COG3148@2|Bacteria,1N0GQ@1224|Proteobacteria,1SAQQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S PFAM DTW domain containing protein - - - - - - - - - - - - DTW k141_28554_2 1123236.KB899382_gene2239 7.21e-83 256.0 28UR3@1|root,2ZGVE@2|Bacteria,1RB70@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_9530_9 1116375.VEJY3_11700 1.68e-119 342.0 COG2716@1|root,COG2716@2|Bacteria,1R7W7@1224|Proteobacteria,1RSDP@1236|Gammaproteobacteria,1XVQB@135623|Vibrionales 135623|Vibrionales E glycine cleavage system gcvR - - ko:K03567 ko02026,map02026 - - - ko00000,ko00001,ko03000 - - - ACT_6 k141_9530_10 672.VV93_v1c22060 5.33e-27 105.0 COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,1RNH9@1236|Gammaproteobacteria,1XUPA@135623|Vibrionales 135623|Vibrionales E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) dapA GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008840,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS k141_32121_1 42565.FP66_07810 1.18e-38 132.0 COG1863@1|root,COG1863@2|Bacteria,1RB2I@1224|Proteobacteria,1S4XR@1236|Gammaproteobacteria 1236|Gammaproteobacteria P COG1863 Multisubunit Na H antiporter, MnhE subunit - - - ko:K05569 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - MNHE k141_32121_2 42565.FP66_07805 6.36e-40 134.0 COG2212@1|root,COG2212@2|Bacteria,1N7BC@1224|Proteobacteria 1224|Proteobacteria P Multisubunit Na H antiporter, MnhF subunit mnhF - - ko:K05563,ko:K05570 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - MrpF_PhaF k141_32121_3 42565.FP66_07800 4.18e-71 216.0 COG1320@1|root,COG1320@2|Bacteria,1RH17@1224|Proteobacteria,1S6Q4@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Na H antiporter - - - ko:K05571 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - PhaG_MnhG_YufB k141_15506_1 218284.CCDN010000008_gene4170 1.84e-156 446.0 COG0192@1|root,COG0192@2|Bacteria,1TPCV@1239|Firmicutes,4HB33@91061|Bacilli,1ZBHR@1386|Bacillus 91061|Bacilli H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme metK GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 M00034,M00035,M00368,M00609 R00177,R04771 RC00021,RC01211 ko00000,ko00001,ko00002,ko01000 - - - S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N k141_5991_1 911045.PSE_3737 9.87e-40 159.0 COG1289@1|root,COG1289@2|Bacteria 2|Bacteria S transmembrane transporter activity VPA1578 - - - - - - - - - - - FUSC k141_34508_1 1116375.VEJY3_17666 1.85e-144 413.0 2DMIH@1|root,32RT1@2|Bacteria,1RDKU@1224|Proteobacteria,1S9NM@1236|Gammaproteobacteria,1Y2RW@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_34508_2 223926.28809561 8.99e-275 754.0 COG2195@1|root,COG2195@2|Bacteria,1MV7D@1224|Proteobacteria,1RMKZ@1236|Gammaproteobacteria,1XTBU@135623|Vibrionales 135623|Vibrionales E Cleaves the N-terminal amino acid of tripeptides pepT GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564 3.4.11.4 ko:K01258 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20,Peptidase_M42 k141_34508_3 1219076.N646_3923 6.17e-107 308.0 COG2131@1|root,COG2131@2|Bacteria,1RD1P@1224|Proteobacteria,1T01V@1236|Gammaproteobacteria,1Y2XW@135623|Vibrionales 135623|Vibrionales F MafB19-like deaminase - - 3.5.4.12 ko:K01493 ko00240,ko01100,map00240,map01100 M00429 R01663 RC00074 ko00000,ko00001,ko00002,ko01000,ko02044 - - - dCMP_cyt_deam_1 k141_34508_4 223926.28809559 9.57e-223 619.0 COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,1RPI1@1236|Gammaproteobacteria,1XTHC@135623|Vibrionales 135623|Vibrionales M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K03585 ko01501,ko01503,map01501,map01503 M00646,M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,8.A.1.6 - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 k141_30956_1 1453501.JELR01000001_gene2012 4.05e-29 107.0 COG5645@1|root,COG5645@2|Bacteria,1NJDD@1224|Proteobacteria,1SGGJ@1236|Gammaproteobacteria,46958@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF1375) - - - - - - - - - - - - DUF1375 k141_27366_1 1453501.JELR01000002_gene562 1.68e-29 114.0 COG1024@1|root,COG1024@2|Bacteria,1MU0B@1224|Proteobacteria,1RN07@1236|Gammaproteobacteria,464P0@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1024 Enoyl-CoA hydratase carnithine racemase - - - - - - - - - - - - ECH_2 k141_27507_7 1279017.AQYJ01000029_gene3812 2.82e-208 577.0 COG0583@1|root,COG0583@2|Bacteria,1N663@1224|Proteobacteria,1RMFD@1236|Gammaproteobacteria,463Y0@72275|Alteromonadaceae 1236|Gammaproteobacteria K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_27507_8 1453501.JELR01000001_gene2290 0.0 1001.0 COG2224@1|root,COG2224@2|Bacteria,1MWIF@1224|Proteobacteria,1RQAK@1236|Gammaproteobacteria,4659E@72275|Alteromonadaceae 1236|Gammaproteobacteria C Isocitrate lyase aceA - 4.1.3.1 ko:K01637 ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200 M00012 R00479 RC00311,RC00313 ko00000,ko00001,ko00002,ko01000 - - - ICL k141_27507_9 1042377.AFPJ01000007_gene1760 2.91e-171 492.0 COG0282@1|root,COG0282@2|Bacteria,1MW61@1224|Proteobacteria,1RMKB@1236|Gammaproteobacteria,464JF@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction ackA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006083,GO:0006091,GO:0006113,GO:0006629,GO:0006631,GO:0006633,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0008776,GO:0009058,GO:0009987,GO:0015980,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0016999,GO:0017000,GO:0017144,GO:0019413,GO:0019541,GO:0019542,GO:0019752,GO:0032787,GO:0042710,GO:0043167,GO:0043169,GO:0043436,GO:0044010,GO:0044011,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046394,GO:0046459,GO:0046872,GO:0046914,GO:0051703,GO:0051704,GO:0051790,GO:0055114,GO:0071704,GO:0072330,GO:0090605,GO:0090609,GO:1901576 2.7.2.1 ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00315,R01353 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - iSDY_1059.SDY_2492,iYL1228.KPN_02687 Acetate_kinase k141_27507_10 1453501.JELR01000001_gene2288 0.0 1087.0 COG0280@1|root,COG0857@1|root,COG0280@2|Bacteria,COG0857@2|Bacteria,1QTS5@1224|Proteobacteria,1RMJS@1236|Gammaproteobacteria,464SE@72275|Alteromonadaceae 1236|Gammaproteobacteria C belongs to the CobB CobQ family pta GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006083,GO:0006084,GO:0006085,GO:0006091,GO:0006113,GO:0006139,GO:0006163,GO:0006164,GO:0006520,GO:0006566,GO:0006567,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008959,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015980,GO:0016053,GO:0016054,GO:0016407,GO:0016740,GO:0016746,GO:0016747,GO:0016999,GO:0017000,GO:0017001,GO:0017144,GO:0018130,GO:0019413,GO:0019427,GO:0019438,GO:0019541,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0042737,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045733,GO:0046390,GO:0046394,GO:0046395,GO:0046459,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0070689,GO:0071616,GO:0071704,GO:0072329,GO:0072330,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606 2.3.1.8 ko:K13788 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00230,R00921 RC00004,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000 - - iG2583_1286.G2583_2834,iYL1228.KPN_02688 AAA_26,DRTGG,PTA_PTB k141_27507_11 1337936.IJ00_24745 3.7e-49 157.0 COG2329@1|root,COG2329@2|Bacteria,1G7DQ@1117|Cyanobacteria,1HNZK@1161|Nostocales 1117|Cyanobacteria S Antibiotic biosynthesis monooxygenase - - - - - - - - - - - - ABM k141_27507_12 1279017.AQYJ01000029_gene3808 0.0 971.0 COG0427@1|root,COG0427@2|Bacteria,1PJY0@1224|Proteobacteria,1RPS6@1236|Gammaproteobacteria,46523@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG0427 Acetyl-CoA hydrolase - - - - - - - - - - - - AcetylCoA_hyd_C k141_27507_13 1279017.AQYJ01000029_gene3807 0.0 1246.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RPM5@1236|Gammaproteobacteria,4657E@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1960 Acyl-CoA dehydrogenases fadE - 1.3.8.7 ko:K00249,ko:K06445 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,DUF1974 k141_27507_14 1279017.AQYJ01000029_gene3806 3.21e-93 274.0 COG0684@1|root,COG0684@2|Bacteria,1RH18@1224|Proteobacteria,1RS9U@1236|Gammaproteobacteria,466UJ@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions rraA GO:0003674,GO:0004857,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008428,GO:0009892,GO:0009894,GO:0009895,GO:0010605,GO:0019219,GO:0019222,GO:0030234,GO:0031323,GO:0031324,GO:0031329,GO:0031330,GO:0032069,GO:0032074,GO:0043086,GO:0044092,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060699,GO:0060700,GO:0060701,GO:0060702,GO:0065007,GO:0065009,GO:0080090,GO:0098772,GO:1902369 - ko:K02553 - - - - ko00000,ko03019 - - iJR904.b3929 RraA-like k141_3814_1 1294265.JCM21738_330 2.56e-93 274.0 COG1871@1|root,COG1871@2|Bacteria,1V70X@1239|Firmicutes,4HIVG@91061|Bacilli,1ZGE3@1386|Bacillus 91061|Bacilli NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase cheD - 3.5.1.44 ko:K03411 ko02030,map02030 - - - ko00000,ko00001,ko01000,ko02035 - - - CheD k141_3814_2 1380408.AVGH01000006_gene2456 9.67e-09 53.1 COG1776@1|root,COG1776@2|Bacteria,1UNKB@1239|Firmicutes,4HB40@91061|Bacilli,21WHJ@150247|Anoxybacillus 91061|Bacilli NT CheC-like family cheC GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0050896,GO:0050918 - ko:K03410 ko02030,map02030 - - - ko00000,ko00001,ko02035 - - - CheC,CheX k141_23965_1 1294265.JCM21738_5067 4.42e-126 366.0 COG0535@1|root,COG0535@2|Bacteria,1TR52@1239|Firmicutes,4HAY2@91061|Bacilli,1ZBK3@1386|Bacillus 91061|Bacilli C Fe-S oxidoreductases - - - ko:K22227 - - - - ko00000 - - - Fer4_12,Fer4_14,Radical_SAM,SPASM k141_6255_1 203122.Sde_0425 2.21e-105 317.0 COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,1RMSS@1236|Gammaproteobacteria,4651Y@72275|Alteromonadaceae 1236|Gammaproteobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_int_SAM_4,Phage_integrase k141_2617_2 1151127.KB906327_gene1596 0.000774 41.6 2BIFP@1|root,32CN9@2|Bacteria,1QRHG@1224|Proteobacteria,1RUHQ@1236|Gammaproteobacteria,1YR02@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria M Prokaryotic lipoprotein-attachment site lppL - - - - - - - - - - - LPAM_2 k141_19196_1 218284.CCDN010000002_gene2378 9.14e-64 204.0 COG1622@1|root,COG1622@2|Bacteria,1TRC3@1239|Firmicutes,4HADQ@91061|Bacilli,1ZAP8@1386|Bacillus 91061|Bacilli C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) - - - - - - - - - - - - COX2,COX2_TM,Cytochrom_C k141_19196_2 218284.CCDN010000002_gene2252 1.24e-23 99.0 COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,4HBUS@91061|Bacilli,1ZB01@1386|Bacillus 91061|Bacilli EH Belongs to the TPP enzyme family ydaP - 1.2.3.3 ko:K00158 ko00620,ko01100,map00620,map01100 - R00207 RC02745 ko00000,ko00001,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N k141_37011_1 1274524.BSONL12_06933 3.41e-53 176.0 COG1424@1|root,COG1424@2|Bacteria,1V38Y@1239|Firmicutes,4HJME@91061|Bacilli,1ZEA6@1386|Bacillus 91061|Bacilli H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP bioW - 6.2.1.14 ko:K01906 ko00780,ko01100,map00780,map01100 M00577 R03209 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - BioW k141_4933_1 223926.28809536 3.55e-204 572.0 COG1914@1|root,COG1914@2|Bacteria,1P45T@1224|Proteobacteria,1RPT0@1236|Gammaproteobacteria,1XUAT@135623|Vibrionales 135623|Vibrionales P Natural resistance-associated macrophage protein - - - - - - - - - - - - Nramp k141_4933_2 1116375.VEJY3_17766 3.03e-147 415.0 COG0302@1|root,COG0302@2|Bacteria,1MY3N@1224|Proteobacteria,1RMQM@1236|Gammaproteobacteria,1XUKF@135623|Vibrionales 135623|Vibrionales F GTP cyclohydrolase folE GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006082,GO:0006575,GO:0006725,GO:0006729,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0019752,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 ko:K01495 ko00790,ko01100,map00790,map01100 M00126,M00841,M00842,M00843 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 - - - GTP_cyclohydroI k141_4933_3 1280001.BAOA01000136_gene1935 2.49e-263 723.0 COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,1RMQU@1236|Gammaproteobacteria,1XSIM@135623|Vibrionales 135623|Vibrionales H molybdopterin biosynthesis moeA - 2.10.1.1 ko:K03750 ko00790,ko01100,map00790,map01100 - R09735 RC03462 ko00000,ko00001,ko01000 - - - MoCF_biosynth,MoeA_C,MoeA_N k141_4953_1 218284.CCDN010000001_gene1362 4.73e-92 289.0 COG1193@1|root,COG1193@2|Bacteria,1TQWB@1239|Firmicutes,4HAHW@91061|Bacilli,1ZC6C@1386|Bacillus 91061|Bacilli L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity mutS1 - - ko:K07456 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_V k141_9694_1 218284.CCDN010000001_gene1453 9.78e-68 213.0 COG0476@1|root,COG0476@2|Bacteria,1TQ3U@1239|Firmicutes,4HBGP@91061|Bacilli,1ZBR4@1386|Bacillus 91061|Bacilli H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 moeB - 2.7.7.73,2.7.7.80 ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07459 RC00043 ko00000,ko00001,ko01000 - - - ThiF k141_9694_2 218284.CCDN010000001_gene1454 1.19e-44 151.0 COG0351@1|root,COG0351@2|Bacteria,1TQ4A@1239|Firmicutes,4HAAH@91061|Bacilli,1ZCQT@1386|Bacillus 91061|Bacilli H Phosphomethylpyrimidine kinase thiD - 2.7.1.49,2.7.4.7 ko:K00941 ko00730,ko01100,map00730,map01100 M00127 R03471,R04509 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Phos_pyr_kin k141_19220_2 218284.CCDN010000002_gene2228 3.2e-84 257.0 COG2313@1|root,COG2313@2|Bacteria,1TR5J@1239|Firmicutes,4HC38@91061|Bacilli,1ZDAP@1386|Bacillus 91061|Bacilli Q Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway psuG - 4.2.1.70 ko:K16329 ko00240,map00240 - R01055 RC00432,RC00433 ko00000,ko00001,ko01000 - - - Indigoidine_A k141_1383_2 1453501.JELR01000002_gene125 1.33e-46 157.0 COG1670@1|root,COG1670@2|Bacteria,1N18Y@1224|Proteobacteria,1S8ZQ@1236|Gammaproteobacteria,46819@72275|Alteromonadaceae 1236|Gammaproteobacteria J Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_3 k141_9695_1 997296.PB1_06042 2.05e-80 254.0 COG1120@1|root,COG1120@2|Bacteria,1TP2Q@1239|Firmicutes,4HA28@91061|Bacilli,1ZASR@1386|Bacillus 91061|Bacilli HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components yvrA - 3.6.3.34 ko:K02013 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 - - ABC_tran,CbiZ k141_10895_1 1206101.AZXC01000014_gene680 3.97e-52 184.0 COG0021@1|root,COG0021@2|Bacteria,2GJ1K@201174|Actinobacteria 201174|Actinobacteria G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate tkt - 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C,Transketolase_N k141_329_1 1219076.N646_1981 5.21e-07 51.6 COG3710@1|root,COG3710@2|Bacteria,1R52Q@1224|Proteobacteria,1RQY5@1236|Gammaproteobacteria,1XVDH@135623|Vibrionales 135623|Vibrionales K Transcriptional activator CadC cadC - - ko:K03765 - - - - ko00000,ko03000 - - - Trans_reg_C k141_3842_1 1294265.JCM21738_2656 6.56e-11 61.2 COG0411@1|root,COG0411@2|Bacteria,1TR0P@1239|Firmicutes,4HASG@91061|Bacilli,1ZB0Q@1386|Bacillus 91061|Bacilli E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component - - - ko:K01995 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C k141_3842_2 1033734.CAET01000027_gene879 2.43e-123 356.0 COG0410@1|root,COG0410@2|Bacteria,1TPW4@1239|Firmicutes,4HABJ@91061|Bacilli,1ZDVC@1386|Bacillus 91061|Bacilli E branched-chain amino acid - - - ko:K01996 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran k141_3842_3 1294265.JCM21738_2659 5.7e-118 356.0 COG0559@1|root,COG4177@1|root,COG0559@2|Bacteria,COG4177@2|Bacteria,1TPMZ@1239|Firmicutes,4HBB8@91061|Bacilli,1ZBKN@1386|Bacillus 91061|Bacilli E Belongs to the binding-protein-dependent transport system permease family - - - ko:K01998,ko:K11961 ko02010,ko02024,map02010,map02024 M00237,M00323 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4,3.A.1.4.4,3.A.1.4.5 - - BPD_transp_2 k141_35853_1 1220589.CD32_12790 4.12e-27 109.0 COG1055@1|root,COG1055@2|Bacteria,1TPNN@1239|Firmicutes,4H9WV@91061|Bacilli,3IZFR@400634|Lysinibacillus 91061|Bacilli P Arsenical pump membrane protein - - - ko:K03893 - - - - ko00000,ko02000 2.A.45.1,3.A.4.1 - - ArsB k141_9696_1 379066.GAU_1562 7.07e-37 134.0 COG0084@1|root,COG0084@2|Bacteria,1ZST0@142182|Gemmatimonadetes 142182|Gemmatimonadetes L TatD related DNase - - - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase k141_19221_1 218284.CCDN010000005_gene3257 1.42e-117 343.0 COG1307@1|root,COG1307@2|Bacteria,1TQDI@1239|Firmicutes,4HAYQ@91061|Bacilli,1ZCK2@1386|Bacillus 91061|Bacilli S protein conserved in bacteria yitS - - - - - - - - - - - DegV k141_8546_1 1279017.AQYJ01000029_gene3646 1.67e-218 621.0 COG1506@1|root,COG1506@2|Bacteria,1MUJ3@1224|Proteobacteria,1RRN4@1236|Gammaproteobacteria,465BC@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases pqqM - - - - - - - - - - - PD40,Peptidase_S9 k141_8546_2 1453501.JELR01000001_gene2140 8.64e-96 281.0 COG0782@1|root,COG0782@2|Bacteria,1RAP0@1224|Proteobacteria,1S40Q@1236|Gammaproteobacteria,466UU@72275|Alteromonadaceae 1236|Gammaproteobacteria K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length greB - - ko:K04760 - - - - ko00000,ko03021 - - - GreA_GreB,GreA_GreB_N k141_6294_1 1307436.PBF_05778 5.41e-94 281.0 COG2822@1|root,COG2822@2|Bacteria,1TS89@1239|Firmicutes,4HB0W@91061|Bacilli,1ZC6N@1386|Bacillus 91061|Bacilli P periplasmic lipoprotein involved in iron transport ycdO GO:0000041,GO:0006810,GO:0006811,GO:0006812,GO:0006826,GO:0008150,GO:0015684,GO:0030001,GO:0051179,GO:0051234,GO:0070838,GO:0072511 - ko:K07224 - - - - ko00000,ko02000 2.A.108.2.3 - - Peptidase_M75 k141_6294_2 997296.PB1_11849 0.000804 41.6 COG2837@1|root,COG2837@2|Bacteria,1UY9Y@1239|Firmicutes,4HACQ@91061|Bacilli,1ZEAD@1386|Bacillus 91061|Bacilli P Dyp-type peroxidase family protein ywbN GO:0005575,GO:0005576 - ko:K07223,ko:K16301 - - - - ko00000,ko01000,ko02000 2.A.108.2.3 - iYO844.BSU38260 Dyp_perox,TAT_signal k141_10896_1 218284.CCDN010000007_gene3960 3.62e-102 323.0 COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,1TQAD@1239|Firmicutes,4HCMS@91061|Bacilli,1ZBF6@1386|Bacillus 91061|Bacilli EI Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly icmF GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046906,GO:0046983,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 ko:K11942 - - - - ko00000,ko01000 - - - ArgK,B12-binding,MM_CoA_mutase k141_28811_1 42565.FP66_07115 1.13e-157 450.0 COG0281@1|root,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,1RN5F@1236|Gammaproteobacteria,1XI7B@135619|Oceanospirillales 135619|Oceanospirillales C Malate dehydrogenase maeB - 1.1.1.38,1.1.1.40 ko:K00027,ko:K00029 ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020 M00169,M00172 R00214,R00216 RC00105 ko00000,ko00001,ko00002,ko01000 - - - Malic_M,malic k141_3843_1 935863.AWZR01000004_gene437 1.44e-31 123.0 COG0500@1|root,COG2226@2|Bacteria,1PA5F@1224|Proteobacteria,1RY7A@1236|Gammaproteobacteria,1X53I@135614|Xanthomonadales 135614|Xanthomonadales H Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway bioC - 2.1.1.197 ko:K02169 ko00780,ko01100,map00780,map01100 M00572 R09543 RC00003,RC00460 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_11 k141_12166_1 218284.CCDN010000002_gene2177 4.09e-121 351.0 COG0714@1|root,COG0714@2|Bacteria,1TPKR@1239|Firmicutes,4HDUX@91061|Bacilli,1ZAQ6@1386|Bacillus 91061|Bacilli S ATPase family associated with various cellular activities (AAA) - - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 k141_9697_1 1279017.AQYJ01000018_gene828 4.19e-12 68.9 COG3751@1|root,COG3751@2|Bacteria,1NAUK@1224|Proteobacteria,1S2G4@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Putative 2OG-Fe(II) oxygenase - - - - - - - - - - - - 2OG-FeII_Oxy_5 k141_21661_1 1116375.VEJY3_09050 2.21e-220 607.0 COG3039@1|root,COG3039@2|Bacteria,1MXTN@1224|Proteobacteria,1RM94@1236|Gammaproteobacteria,1XVGA@135623|Vibrionales 135623|Vibrionales L User locus_tag - - - - - - - - - - - - DDE_Tnp_1_5 k141_21661_2 1517681.HW45_09985 6.03e-145 417.0 COG3386@1|root,COG3386@2|Bacteria,1MWTR@1224|Proteobacteria,1RSKQ@1236|Gammaproteobacteria,1XXDW@135623|Vibrionales 135623|Vibrionales G SMP-30/Gluconolaconase/LRE-like region - - - ko:K14274 ko00040,map00040 - R02427 RC00713 ko00000,ko00001,ko01000 - - - SGL k141_21661_3 1517681.HW45_09980 7.19e-152 431.0 COG1414@1|root,COG1414@2|Bacteria,1R5ZB@1224|Proteobacteria,1RY6E@1236|Gammaproteobacteria,1XX4V@135623|Vibrionales 135623|Vibrionales K Bacterial transcriptional regulator - - - - - - - - - - - - HTH_IclR,IclR k141_21661_4 1517681.HW45_09895 1.83e-140 402.0 COG1414@1|root,COG1414@2|Bacteria,1R5ZB@1224|Proteobacteria,1RY6E@1236|Gammaproteobacteria,1XZWK@135623|Vibrionales 135623|Vibrionales K Bacterial transcriptional regulator - - - - - - - - - - - - IclR k141_21661_5 1051646.VITU9109_15958 0.0 1733.0 COG1470@1|root,COG1858@1|root,COG3391@1|root,COG4625@1|root,COG5276@1|root,COG1470@2|Bacteria,COG1858@2|Bacteria,COG3391@2|Bacteria,COG4625@2|Bacteria,COG5276@2|Bacteria,1PF0U@1224|Proteobacteria,1T9X1@1236|Gammaproteobacteria,1Y027@135623|Vibrionales 135623|Vibrionales C repeat protein - - - - - - - - - - - - - k141_10897_1 1123236.KB899377_gene393 2.56e-120 348.0 COG4757@1|root,COG4757@2|Bacteria,1Q1V6@1224|Proteobacteria,1RT3H@1236|Gammaproteobacteria,466ZC@72275|Alteromonadaceae 1236|Gammaproteobacteria S Alpha beta hydrolase - - - - - - - - - - - - Abhydrolase_1,Hydrolase_4 k141_2648_1 1294265.JCM21738_4418 8.59e-102 297.0 29DTM@1|root,32UXJ@2|Bacteria,1VEA3@1239|Firmicutes,4HN2P@91061|Bacilli,1ZFX9@1386|Bacillus 91061|Bacilli S AmiS/UreI family transporter - - - ko:K22112 - - - - ko00000,ko02000 1.A.29.1.1,1.A.29.1.2,1.A.29.1.6 - - AmiS_UreI k141_2648_2 1294265.JCM21738_4417 9.6e-86 253.0 COG0295@1|root,COG0295@2|Bacteria,1V6IP@1239|Firmicutes,4HIJ3@91061|Bacilli,1ZG79@1386|Bacillus 91061|Bacilli F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis cdd - 3.5.4.5 ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R01878,R02485,R08221 RC00074,RC00514 ko00000,ko00001,ko01000 - - - dCMP_cyt_deam_1 k141_18128_1 1423321.AS29_15960 1.46e-158 452.0 COG1219@1|root,COG1219@2|Bacteria,1TQ00@1239|Firmicutes,4H9U4@91061|Bacilli,1ZANE@1386|Bacillus 91061|Bacilli O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP clpX GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - ko:K03544 ko04112,map04112 - - - ko00000,ko00001,ko03110 - - - AAA_2,ClpB_D2-small,zf-C4_ClpX k141_13336_1 1280689.AUJC01000011_gene1535 1.38e-17 88.2 COG2866@1|root,COG2866@2|Bacteria,1VN0F@1239|Firmicutes 1239|Firmicutes E Protein of unknown function (DUF2817) - - - - - - - - - - - - Peptidase_M14 k141_29893_2 1453501.JELR01000001_gene2202 5.81e-64 199.0 2DQ9F@1|root,335FN@2|Bacteria,1NEEU@1224|Proteobacteria,1SGG8@1236|Gammaproteobacteria,468GA@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF2489) - - - - - - - - - - - - DUF2489 k141_29893_3 1279017.AQYJ01000029_gene3737 1.67e-221 615.0 COG2265@1|root,COG2265@2|Bacteria,1MY45@1224|Proteobacteria,1RN2B@1236|Gammaproteobacteria,4645S@72275|Alteromonadaceae 1236|Gammaproteobacteria J Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA) trmA GO:0000049,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016740,GO:0016741,GO:0019843,GO:0030488,GO:0030696,GO:0030697,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363 2.1.1.35 ko:K00557 - - - - ko00000,ko01000,ko03016 - - - tRNA_U5-meth_tr k141_29893_4 523791.Kkor_0580 1.07e-55 177.0 COG0432@1|root,COG0432@2|Bacteria,1RH13@1224|Proteobacteria,1S3VP@1236|Gammaproteobacteria,1XJR3@135619|Oceanospirillales 135619|Oceanospirillales S Uncharacterised protein family UPF0047 - - - - - - - - - - - - UPF0047 k141_29893_5 1279017.AQYJ01000029_gene3740 1.38e-58 182.0 COG2920@1|root,COG2920@2|Bacteria,1RGVG@1224|Proteobacteria,1S5ZA@1236|Gammaproteobacteria,467QI@72275|Alteromonadaceae 1236|Gammaproteobacteria P Part of a sulfur-relay system tusE GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097163,GO:0140104,GO:1901360 - ko:K11179 ko04122,map04122 - - - ko00000,ko00001,ko01000,ko03016 - - - DsrC k141_22801_1 218284.CCDN010000002_gene2751 4.08e-103 308.0 COG0601@1|root,COG0601@2|Bacteria,1UYTT@1239|Firmicutes,4IEZM@91061|Bacilli,1ZJ9K@1386|Bacillus 91061|Bacilli EP Binding-protein-dependent transport system inner membrane component - - - - - - - - - - - - BPD_transp_1 k141_26457_1 997296.PB1_15384 6.53e-20 82.0 COG1534@1|root,COG1534@2|Bacteria,1VEGM@1239|Firmicutes,4HKC7@91061|Bacilli,1ZH83@1386|Bacillus 91061|Bacilli J RNA-binding protein containing KH domain, possibly ribosomal protein yhbY - - ko:K07574 - - - - ko00000,ko03009 - - - CRS1_YhbY k141_26457_2 218284.CCDN010000001_gene716 2.32e-103 301.0 COG1057@1|root,COG1057@2|Bacteria,1V3SK@1239|Firmicutes,4HGXK@91061|Bacilli,1ZFIV@1386|Bacillus 91061|Bacilli H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) nadD GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 ko:K00969 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like k141_8547_1 1453501.JELR01000001_gene1995 2.53e-63 202.0 COG1694@1|root,COG3956@2|Bacteria,1MVKM@1224|Proteobacteria,1RNVU@1236|Gammaproteobacteria,465UD@72275|Alteromonadaceae 1236|Gammaproteobacteria S Pyrophosphatase mazG GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009267,GO:0009394,GO:0009605,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042594,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.9 ko:K04765 ko00230,ko00240,ko00760,ko00770,ko01100,map00230,map00240,map00760,map00770,map01100 - R00086,R00087,R00103,R00287,R00426,R00515,R00662,R00720,R03004,R03036,R11323 RC00002 ko00000,ko00001,ko01000 - - iAF1260.b2781,iBWG_1329.BWG_2516,iE2348C_1286.E2348C_3048,iEC55989_1330.EC55989_3056,iECDH10B_1368.ECDH10B_2948,iECDH1ME8569_1439.ECDH1ME8569_2691,iECH74115_1262.ECH74115_4041,iECIAI1_1343.ECIAI1_2889,iECO103_1326.ECO103_3324,iECO111_1330.ECO111_3505,iECO26_1355.ECO26_3851,iECOK1_1307.ECOK1_3155,iECP_1309.ECP_2762,iECSE_1348.ECSE_3039,iECSP_1301.ECSP_3733,iECW_1372.ECW_m2990,iECs_1301.ECs3641,iEKO11_1354.EKO11_0987,iEcDH1_1363.EcDH1_0907,iEcE24377_1341.EcE24377A_3085,iEcHS_1320.EcHS_A2925,iEcolC_1368.EcolC_0931,iG2583_1286.G2583_3433,iJO1366.b2781,iJR904.b2781,iSBO_1134.SBO_2662,iSSON_1240.SSON_2938,iSbBS512_1146.SbBS512_E3092,iUMN146_1321.UM146_02665,iUMNK88_1353.UMNK88_3464,iUTI89_1310.UTI89_C3150,iWFL_1372.ECW_m2990,iY75_1357.Y75_RS14470,iZ_1308.Z4096 MazG k141_8547_2 1173263.Syn7502_02432 9.57e-31 117.0 COG1052@1|root,COG1052@2|Bacteria,1G028@1117|Cyanobacteria,1GZTS@1129|Synechococcus 1117|Cyanobacteria C D-isomer specific 2-hydroxyacid dehydrogenase ddh - 1.1.1.28 ko:K03778 ko00620,ko01120,map00620,map01120 - R00704 RC00044 ko00000,ko00001,ko01000 - - - 2-Hacid_dh,2-Hacid_dh_C k141_9699_1 643648.Slip_1606 5.93e-25 103.0 COG1484@1|root,COG1484@2|Bacteria,1UYIT@1239|Firmicutes,24DFX@186801|Clostridia,42KKU@68298|Syntrophomonadaceae 186801|Clostridia L IstB-like ATP binding protein - - - - - - - - - - - - IstB_IS21 k141_9699_2 485913.Krac_6942 1.29e-12 71.6 COG4584@1|root,COG4584@2|Bacteria,2G808@200795|Chloroflexi 200795|Chloroflexi L Integrase core domain - - - - - - - - - - - - rve k141_32243_1 1318628.MARLIPOL_08434 9.24e-22 91.7 COG2513@1|root,COG2513@2|Bacteria,1N4VT@1224|Proteobacteria,1RMR5@1236|Gammaproteobacteria,464GF@72275|Alteromonadaceae 1236|Gammaproteobacteria G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate prpB GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006113,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0015980,GO:0016042,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019752,GO:0032787,GO:0042737,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0046421,GO:0046459,GO:0046872,GO:0055114,GO:0071704,GO:0072329,GO:1901575 4.1.3.30 ko:K03417 ko00640,map00640 - R00409 RC00286,RC00287 ko00000,ko00001,ko01000 - - iECNA114_1301.ECNA114_0319,iECP_1309.ECP_0407 PEP_mutase k141_32243_2 1279017.AQYJ01000025_gene645 4.07e-129 370.0 COG1802@1|root,COG1802@2|Bacteria,1NDRT@1224|Proteobacteria,1RYXQ@1236|Gammaproteobacteria,466TS@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG1802 Transcriptional regulators - - - - - - - - - - - - FCD,GntR k141_32243_3 1279017.AQYJ01000025_gene646 1.44e-106 309.0 COG3216@1|root,COG3216@2|Bacteria,1RGV6@1224|Proteobacteria,1S682@1236|Gammaproteobacteria,467DJ@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria TLL0138 - - ko:K09928 - - - - ko00000 - - - DUF2062 k141_23987_1 1499968.TCA2_0732 1.18e-91 276.0 COG2421@1|root,COG2421@2|Bacteria,1TQ67@1239|Firmicutes,4HA9D@91061|Bacilli,26VMV@186822|Paenibacillaceae 91061|Bacilli C Acetamidase/Formamidase family - - - - - - - - - - - - FmdA_AmdA k141_22802_2 1042377.AFPJ01000042_gene1025 3.37e-34 131.0 2DB83@1|root,2Z7Q0@2|Bacteria,1NWYZ@1224|Proteobacteria,1SPD0@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF4127) - - - - - - - - - - - - DUF4127 k141_2649_1 997884.HMPREF1068_04375 4.79e-10 59.7 COG0652@1|root,COG0652@2|Bacteria,4NGT6@976|Bacteroidetes,2FMZ6@200643|Bacteroidia,4ANA5@815|Bacteroidaceae 976|Bacteroidetes M PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides - - 5.2.1.8 ko:K01802,ko:K03768 - - - - ko00000,ko01000,ko03110 - - - Pro_isomerase k141_2649_2 1294265.JCM21738_1324 3.38e-40 133.0 2EG47@1|root,339W6@2|Bacteria,1VMG4@1239|Firmicutes,4HRAK@91061|Bacilli,1ZK0D@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_333_1 1294265.JCM21738_518 2.96e-08 53.5 COG0563@1|root,COG0563@2|Bacteria,1V1QU@1239|Firmicutes,4HGI2@91061|Bacilli,1ZGS7@1386|Bacillus 91061|Bacilli F COG0563 Adenylate kinase and related kinases - - - - - - - - - - - - AAA_18,SKI k141_333_2 1294265.JCM21738_519 2.29e-89 263.0 COG0454@1|root,COG0456@2|Bacteria,1VBAA@1239|Firmicutes,4HN0D@91061|Bacilli,1ZQXX@1386|Bacillus 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1 k141_35855_2 1026882.MAMP_02136 6.4e-19 88.2 COG0642@1|root,COG2205@2|Bacteria,1N1Z2@1224|Proteobacteria,1RPG9@1236|Gammaproteobacteria,460R7@72273|Thiotrichales 72273|Thiotrichales T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - 2.7.13.3 ko:K07645 ko02020,ko02024,map02020,map02024 M00453 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - 2CSK_N,HATPase_c,HisKA k141_6295_1 218284.CCDN010000001_gene1086 7.5e-46 153.0 COG2339@1|root,COG2339@2|Bacteria,1UZGQ@1239|Firmicutes,4HCGD@91061|Bacilli,1ZBUQ@1386|Bacillus 91061|Bacilli S Involved in the degradation of specific anti-sigma factors prsW - - - - - - - - - - - PrsW-protease k141_6295_2 218284.CCDN010000001_gene1085 9.19e-191 534.0 COG0252@1|root,COG0252@2|Bacteria,1TPP9@1239|Firmicutes,4H9YJ@91061|Bacilli,1ZAZT@1386|Bacillus 91061|Bacilli EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D ansB - 3.5.1.1 ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 - R00485 RC00010,RC02798 ko00000,ko00001,ko01000 - - - Asparaginase k141_6295_3 218284.CCDN010000001_gene1084 1.9e-47 160.0 COG0492@1|root,COG0492@2|Bacteria,1TQGS@1239|Firmicutes,4HBIS@91061|Bacilli,1ZCBR@1386|Bacillus 91061|Bacilli O COG0492 Thioredoxin reductase ypdA - 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Pyr_redox_3 k141_4957_1 1116375.VEJY3_11130 1.73e-155 452.0 COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,1RNYW@1236|Gammaproteobacteria,1XT9K@135623|Vibrionales 135623|Vibrionales OU signal peptide peptidase sppA - - ko:K04773 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S49 k141_4957_2 1116375.VEJY3_11125 2.32e-220 623.0 COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,1RNM8@1236|Gammaproteobacteria,1XTNT@135623|Vibrionales 135623|Vibrionales C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family fadH - 1.3.1.34 ko:K00219 - - - - ko00000,ko01000 - - - Oxidored_FMN,Pyr_redox_2 k141_13337_1 218284.CCDN010000001_gene1042 4.69e-74 233.0 COG1686@1|root,COG1686@2|Bacteria,1TQN0@1239|Firmicutes,4HBCE@91061|Bacilli,1ZB0W@1386|Bacillus 91061|Bacilli M Belongs to the peptidase S11 family dacF GO:0003674,GO:0003824,GO:0004175,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.16.4 ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - PBP5_C,Peptidase_S11 k141_12169_1 218284.CCDN010000002_gene2250 7.85e-126 385.0 COG2273@1|root,COG2273@2|Bacteria,1TR5U@1239|Firmicutes,4HACU@91061|Bacilli,1ZR43@1386|Bacillus 91061|Bacilli G Glycosyl hydrolases family 16 bglA3 - 3.2.1.18 ko:K01186 ko00511,ko00600,ko04142,map00511,map00600,map04142 - R04018 RC00028,RC00077 ko00000,ko00001,ko01000,ko02042 - GH33 - CBM_4_9,Glyco_hydro_16,RicinB_lectin_2 k141_16857_1 240302.BN982_01426 9.32e-141 408.0 COG2866@1|root,COG2866@2|Bacteria,1TQ4D@1239|Firmicutes,4HBBY@91061|Bacilli,3NFQY@45667|Halobacillus 91061|Bacilli E Zinc carboxypeptidase - - - - - - - - - - - - Peptidase_M14 k141_19223_1 1279017.AQYJ01000025_gene567 1.21e-219 639.0 COG1629@1|root,COG4771@2|Bacteria,1N6JG@1224|Proteobacteria,1RP10@1236|Gammaproteobacteria,465FE@72275|Alteromonadaceae 1236|Gammaproteobacteria P Carboxypeptidase regulatory-like domain - - - - - - - - - - - - CarboxypepD_reg,Plug,TonB_dep_Rec k141_26513_1 1121091.AUMP01000040_gene1369 5.67e-84 253.0 COG0406@1|root,COG0406@2|Bacteria,1V3RC@1239|Firmicutes,4HHSJ@91061|Bacilli 91061|Bacilli G Phosphoglycerate mutase - - 5.4.2.11 ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - His_Phos_1 k141_26513_2 997346.HMPREF9374_2085 1.36e-25 99.8 COG0457@1|root,COG0457@2|Bacteria,1V3U6@1239|Firmicutes,4HFWW@91061|Bacilli,27CYZ@186824|Thermoactinomycetaceae 91061|Bacilli S Tetratrico peptide repeat - - - - - - - - - - - - TPR_5,TPR_6,TPR_8 k141_18150_1 550540.Fbal_2353 1.41e-13 65.5 2ETEB@1|root,33KY5@2|Bacteria,1NPIT@1224|Proteobacteria,1SHS9@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - ko:K02651 ko04112,map04112 - - - ko00000,ko00001,ko02035,ko02044 - - - - k141_18150_2 945550.VISI1226_15791 4.97e-14 72.4 COG4960@1|root,COG4960@2|Bacteria,1QKFB@1224|Proteobacteria,1TIJ8@1236|Gammaproteobacteria,1XZ89@135623|Vibrionales 135623|Vibrionales OU COG4960 Flp pilus assembly protein, protease CpaA - - 3.4.23.43 ko:K02278 - - - - ko00000,ko01000,ko02035,ko02044 - - - Peptidase_A24 k141_25223_1 218284.CCDN010000001_gene439 7.6e-98 290.0 COG0500@1|root,COG2226@2|Bacteria,1V46W@1239|Firmicutes,4IPXB@91061|Bacilli 91061|Bacilli Q Mycolic acid cyclopropane synthetase - - - - - - - - - - - - Methyltransf_11 k141_34716_2 218284.CCDN010000006_gene3673 6.42e-12 64.7 COG0626@1|root,COG0626@2|Bacteria,1TPC7@1239|Firmicutes,4HAFQ@91061|Bacilli,1ZAR9@1386|Bacillus 91061|Bacilli E cystathionine - - 2.5.1.48 ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017 R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946 RC00020,RC00056,RC00069,RC00420,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000 - - - Cys_Met_Meta_PP k141_9721_1 218284.CCDN010000006_gene3666 1.21e-60 198.0 COG0265@1|root,COG0265@2|Bacteria,1TSBA@1239|Firmicutes,4HA05@91061|Bacilli,1ZAQG@1386|Bacillus 91061|Bacilli O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain minJ - - - - - - - - - - - PDZ_2 k141_345_1 1042377.AFPJ01000052_gene1582 0.0 1231.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria,4651V@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec k141_2657_2 1279017.AQYJ01000027_gene1568 4.58e-180 507.0 COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,1RMDU@1236|Gammaproteobacteria,465RN@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) miaA GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006417,GO:0006725,GO:0006807,GO:0006950,GO:0008033,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009451,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016070,GO:0016740,GO:0016765,GO:0019222,GO:0031323,GO:0031326,GO:0032268,GO:0033554,GO:0034248,GO:0034470,GO:0034605,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043555,GO:0044237,GO:0044238,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051246,GO:0051716,GO:0052381,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1990497,GO:2000112,GO:2000765 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 - R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 - - - IPPT k141_2657_3 1453501.JELR01000002_gene927 1.44e-52 166.0 COG1923@1|root,COG1923@2|Bacteria,1MZM1@1224|Proteobacteria,1S8W0@1236|Gammaproteobacteria,467WJ@72275|Alteromonadaceae 1236|Gammaproteobacteria J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs hfq GO:0003674,GO:0003676,GO:0003677,GO:0003681,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006417,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016246,GO:0016441,GO:0016458,GO:0017148,GO:0019222,GO:0022607,GO:0022613,GO:0022618,GO:0030423,GO:0031047,GO:0031123,GO:0031124,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032268,GO:0032269,GO:0032270,GO:0034248,GO:0034249,GO:0034250,GO:0034622,GO:0034641,GO:0035194,GO:0040029,GO:0040033,GO:0043170,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045974,GO:0045975,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:2000112,GO:2000113 - ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 - - - ko00000,ko00001,ko03019,ko03036 - - - Hfq k141_15890_1 223926.28807199 0.0 1060.0 COG1025@1|root,COG1025@2|Bacteria,1QTVC@1224|Proteobacteria,1T1IG@1236|Gammaproteobacteria,1XT1Q@135623|Vibrionales 135623|Vibrionales O Belongs to the peptidase M16 family ptrA - - - - - - - - - - - Peptidase_M16,Peptidase_M16_C,Peptidase_M16_M k141_15890_2 223926.28807200 1.62e-42 140.0 2931X@1|root,2ZQJ4@2|Bacteria,1P410@1224|Proteobacteria,1SW3W@1236|Gammaproteobacteria,1XYJP@135623|Vibrionales 135623|Vibrionales - - VP2207 - - - - - - - - - - - - k141_15890_3 223926.28807201 1.37e-258 723.0 COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,1RMZ8@1236|Gammaproteobacteria,1XV3W@135623|Vibrionales 135623|Vibrionales I Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities fadJ GO:0003674,GO:0003824,GO:0003857,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008692,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0016856,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 1.1.1.35,4.2.1.17,5.1.2.3 ko:K01782 ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212 M00032,M00087 R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094 RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 - - - 3HCDH,3HCDH_N,ECH_1 k141_25500_1 1051501.AYTL01000028_gene1877 5.78e-44 151.0 2DY9G@1|root,348S7@2|Bacteria 2|Bacteria S Domain of unknown function (DUF4352) yxkC - - - - - - - - - - - DUF4352 k141_19497_1 1307436.PBF_11722 2.28e-98 299.0 COG0591@1|root,COG0591@2|Bacteria,1V0ME@1239|Firmicutes,4HBCT@91061|Bacilli,1ZQYS@1386|Bacillus 91061|Bacilli E Sodium:solute symporter family - - - - - - - - - - - - SSF k141_30086_1 318464.IO99_07690 2.08e-89 267.0 COG0327@1|root,COG0327@2|Bacteria,1UZ41@1239|Firmicutes,24DN0@186801|Clostridia,36E4E@31979|Clostridiaceae 186801|Clostridia S NIF3 (NGG1p interacting factor 3) - - - - - - - - - - - - NIF3 k141_30086_2 649639.Bcell_0465 3.16e-91 296.0 28HKI@1|root,2Z7VC@2|Bacteria,1UKET@1239|Firmicutes,4ITI3@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - k141_10057_1 913325.N799_01300 4.3e-29 117.0 2EBHX@1|root,335IC@2|Bacteria,1NCYG@1224|Proteobacteria,1SFBM@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_12552_1 218284.CCDN010000011_gene4422 3.21e-154 443.0 COG1721@1|root,COG1721@2|Bacteria,1TUWF@1239|Firmicutes,4HDRE@91061|Bacilli,1ZCAS@1386|Bacillus 91061|Bacilli S conserved protein (some members contain a von Willebrand factor type A (vWA) domain) yeaD - - - - - - - - - - - DUF58 k141_26851_2 1121085.AUCI01000035_gene2023 6.97e-43 150.0 COG2059@1|root,COG2059@2|Bacteria,1TSKA@1239|Firmicutes,4HBB1@91061|Bacilli,1ZDC5@1386|Bacillus 91061|Bacilli P chromate transporter, chromate ion transporter chr - - ko:K07240 - - - - ko00000,ko02000 2.A.51.1 - - Chromate_transp k141_8856_1 1501230.ET33_14620 1.17e-34 136.0 COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1TP98@1239|Firmicutes,4HAQ9@91061|Bacilli,26SV7@186822|Paenibacillaceae 91061|Bacilli J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily pheT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - B3_4,B5,FDX-ACB,tRNA_bind k141_4107_1 29495.EA26_19300 1.26e-74 248.0 COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,1RMS9@1236|Gammaproteobacteria,1XSPJ@135623|Vibrionales 135623|Vibrionales L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate uvrA GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009380,GO:0009381,GO:0009987,GO:0016787,GO:0016788,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran k141_5269_2 1453501.JELR01000002_gene1015 9.18e-135 387.0 COG1040@1|root,COG1040@2|Bacteria,1QV41@1224|Proteobacteria,1RSAP@1236|Gammaproteobacteria,4651C@72275|Alteromonadaceae 1236|Gammaproteobacteria S competence protein - - - - - - - - - - - - - k141_5269_3 1042377.AFPJ01000015_gene1612 2.61e-58 201.0 COG1199@1|root,COG1199@2|Bacteria,1MVRJ@1224|Proteobacteria,1RQ7B@1236|Gammaproteobacteria,464G6@72275|Alteromonadaceae 1236|Gammaproteobacteria KL COG1199 Rad3-related DNA helicases - - 3.6.4.12 ko:K10844 ko03022,ko03420,map03022,map03420 M00290 - - ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - DEAD_2,Helicase_C_2 k141_13691_1 1453501.JELR01000001_gene2829 1.45e-145 426.0 COG2272@1|root,COG2272@2|Bacteria,1MVQZ@1224|Proteobacteria,1RPFW@1236|Gammaproteobacteria,465DX@72275|Alteromonadaceae 1236|Gammaproteobacteria I Carboxylesterase family estA1 - - ko:K03929 - - - - ko00000,ko01000 - CE10 - COesterase k141_34954_1 42565.FP66_15700 1.77e-125 390.0 COG1196@1|root,COG1196@2|Bacteria,1MVNY@1224|Proteobacteria,1RPME@1236|Gammaproteobacteria,1XP02@135619|Oceanospirillales 135619|Oceanospirillales D Protein of unknown function (DUF3584) - - - - - - - - - - - - DUF3584 k141_19498_2 1121929.KB898669_gene3229 2.85e-44 157.0 COG0477@1|root,COG2814@2|Bacteria,1TPRN@1239|Firmicutes,4H9VV@91061|Bacilli,46ZQX@74385|Gracilibacillus 91061|Bacilli EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 k141_2816_1 218284.CCDN010000005_gene3377 7.62e-24 95.1 COG1791@1|root,COG1791@2|Bacteria,1TT4W@1239|Firmicutes,4HFN3@91061|Bacilli,1ZFZ5@1386|Bacillus 91061|Bacilli S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway mtnD GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0010309,GO:0016053,GO:0016491,GO:0016701,GO:0016702,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0051213,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.13.11.53,1.13.11.54 ko:K08967 ko00270,ko01100,map00270,map01100 M00034 R07363,R07364 RC01866,RC02018,RC02118 ko00000,ko00001,ko00002,ko01000 - - - ARD k141_2816_2 997296.PB1_02190 1.14e-58 187.0 COG0235@1|root,COG0235@2|Bacteria,1TT62@1239|Firmicutes,4HHI6@91061|Bacilli,1ZCA2@1386|Bacillus 91061|Bacilli E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) mtnB - 3.1.3.87,4.2.1.109 ko:K08964,ko:K08966 ko00270,ko01100,map00270,map01100 M00034 R07392,R07394 RC01939,RC02074 ko00000,ko00001,ko00002,ko01000 - - - Aldolase_II k141_25501_1 1294265.JCM21738_625 1.44e-98 292.0 COG1792@1|root,COG1792@2|Bacteria,1TR1V@1239|Firmicutes,4HB0K@91061|Bacilli,1ZC8X@1386|Bacillus 91061|Bacilli M Involved in formation and maintenance of cell shape mreC GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0022603,GO:0022604,GO:0030428,GO:0042546,GO:0043621,GO:0044085,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944 - ko:K03570 - - - - ko00000,ko03036 9.B.157.1 - - MreC k141_25501_2 1294265.JCM21738_624 7.22e-60 188.0 COG2891@1|root,COG2891@2|Bacteria,1VEN7@1239|Firmicutes,4HNWW@91061|Bacilli,1ZGID@1386|Bacillus 91061|Bacilli M shape-determining protein mreD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03571 - - - - ko00000,ko03036 9.B.157.1 - - MreD k141_21870_1 82995.CR62_03805 2.61e-07 55.8 2C852@1|root,32YB2@2|Bacteria,1RH28@1224|Proteobacteria,1T179@1236|Gammaproteobacteria,404DT@613|Serratia 1236|Gammaproteobacteria S Domain of unknown function (DUF4136) - - - - - - - - - - - - DUF4136 k141_622_1 218284.CCDN010000006_gene3556 6.83e-63 202.0 COG2141@1|root,COG2141@2|Bacteria,1TPRS@1239|Firmicutes,4H9R2@91061|Bacilli,1ZB1E@1386|Bacillus 91061|Bacilli C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases yceB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - - - - - - - - - - Bac_luciferase k141_622_2 1246626.BleG1_3916 3.97e-35 129.0 2EEF3@1|root,33893@2|Bacteria,1VEUA@1239|Firmicutes,4ICQN@91061|Bacilli,1ZBAX@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_622_3 218284.CCDN010000006_gene3548 2.33e-95 288.0 COG0665@1|root,COG0665@2|Bacteria,1TR1R@1239|Firmicutes,4HB8E@91061|Bacilli,1ZC21@1386|Bacillus 91061|Bacilli E FAD dependent oxidoreductase - - - - - - - - - - - - DAO k141_11228_1 1123229.AUBC01000025_gene4470 1.42e-31 118.0 COG2323@1|root,COG2323@2|Bacteria,1QMVF@1224|Proteobacteria,2VBHE@28211|Alphaproteobacteria,3K0JK@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF421) - - - - - - - - - - - - DUF421 k141_11228_2 218284.CCDN010000002_gene2059 8.38e-36 123.0 2E5KF@1|root,330BM@2|Bacteria,1VEYE@1239|Firmicutes,4HNR3@91061|Bacilli,1ZISS@1386|Bacillus 91061|Bacilli S Small, acid-soluble spore proteins, alpha/beta type - - - - - - - - - - - - SASP k141_36040_1 574375.BAGA_18825 1.64e-23 105.0 COG4926@1|root,COG4926@2|Bacteria,1TQHW@1239|Firmicutes,4HFA8@91061|Bacilli,1ZPV9@1386|Bacillus 91061|Bacilli S Prophage endopeptidase tail - - - - - - - - - - - - Prophage_tail k141_17092_1 218284.CCDN010000001_gene739 8.51e-127 374.0 COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,4HA1G@91061|Bacilli,1ZASC@1386|Bacillus 91061|Bacilli G COG0366 Glycosidases yugT - 3.2.1.10,3.2.1.20 ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00028,R00801,R00802,R01718,R01791,R06087,R06088,R06199 RC00028,RC00049,RC00059,RC00077,RC00451 ko00000,ko00001,ko01000 - GH13,GH31 iSB619.SA_RS07580 Alpha-amylase,Malt_amylase_C k141_34955_1 218284.CCDN010000002_gene2605 9.33e-38 127.0 2E85N@1|root,332J6@2|Bacteria,1VFSE@1239|Firmicutes,4HNIY@91061|Bacilli,1ZISW@1386|Bacillus 91061|Bacilli S Spore coat associated protein JA (CotJA) cotJA - - ko:K06332 - - - - ko00000 - - - CotJA k141_34955_2 218284.CCDN010000001_gene1077 7.03e-47 151.0 2E34J@1|root,32Y4N@2|Bacteria,1VESM@1239|Firmicutes,4HKID@91061|Bacilli,1ZI8X@1386|Bacillus 91061|Bacilli S CotJB protein cotJB - - ko:K06333 - - - - ko00000 - - - CotJB k141_15891_1 218284.CCDN010000001_gene1973 1.03e-171 481.0 COG0395@1|root,COG0395@2|Bacteria,1TR45@1239|Firmicutes,4HCEH@91061|Bacilli,1ZCMK@1386|Bacillus 91061|Bacilli G COG0395 ABC-type sugar transport system, permease component amyC1 - - ko:K10119 ko02010,map02010 M00196 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.28 - - BPD_transp_1 k141_25502_1 1294265.JCM21738_3708 8.56e-50 167.0 COG1009@1|root,COG1009@2|Bacteria,1TQW4@1239|Firmicutes,4H9YR@91061|Bacilli,1ZAZ0@1386|Bacillus 91061|Bacilli CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit nuoL - 1.6.5.3 ko:K00341 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_C,Proton_antipo_M,Proton_antipo_N k141_25502_2 1294265.JCM21738_3709 1.72e-44 155.0 COG1008@1|root,COG1008@2|Bacteria,1UHSH@1239|Firmicutes,4IS87@91061|Bacilli,1ZCNA@1386|Bacillus 91061|Bacilli C COG1008 NADH ubiquinone oxidoreductase subunit 4 (chain M) nuoM - 1.6.5.3 ko:K00342 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q5_N,Proton_antipo_M k141_13692_1 1415755.JQLV01000001_gene3516 6.21e-148 427.0 COG0477@1|root,COG2814@2|Bacteria,1MVQQ@1224|Proteobacteria,1RXEZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria EGP transporter - - - ko:K08369 - - - - ko00000,ko02000 2.A.1 - - MFS_1,MFS_4,Sugar_tr k141_20636_1 42565.FP66_06105 2.38e-223 623.0 COG0057@1|root,COG0057@2|Bacteria,1MZE4@1224|Proteobacteria,1RMSI@1236|Gammaproteobacteria,1XHW4@135619|Oceanospirillales 135619|Oceanospirillales G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family gapA - 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N k141_18383_1 218284.CCDN010000002_gene2221 9.02e-57 179.0 2D7FD@1|root,32TNY@2|Bacteria,1VADP@1239|Firmicutes,4HKCW@91061|Bacilli,1ZI9Y@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF1992) ydhN1 - - - - - - - - - - - DUF1992 k141_18383_3 218284.CCDN010000002_gene2750 9.47e-60 196.0 COG1173@1|root,COG1173@2|Bacteria,1V21B@1239|Firmicutes,4HJ5Y@91061|Bacilli,1ZFPK@1386|Bacillus 91061|Bacilli EP ABC transporter (permease) - - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 k141_4122_1 398511.BpOF4_12855 9.63e-46 162.0 28KI6@1|root,2ZA3G@2|Bacteria,1UYE9@1239|Firmicutes,4HB9Y@91061|Bacilli,1ZF3A@1386|Bacillus 91061|Bacilli S Spore germination B3/ GerAC like, C-terminal - - - - - - - - - - - - Spore_GerAC k141_19528_2 1279017.AQYJ01000025_gene758 1.51e-77 239.0 COG1721@1|root,COG1721@2|Bacteria,1Q7RR@1224|Proteobacteria,1RNNP@1236|Gammaproteobacteria,466HG@72275|Alteromonadaceae 1236|Gammaproteobacteria S conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - - - - - - - - - - DUF58 k141_20659_1 935863.AWZR01000002_gene1078 1.31e-33 129.0 COG0438@1|root,COG0438@2|Bacteria,1MUTA@1224|Proteobacteria,1RS31@1236|Gammaproteobacteria,1X41U@135614|Xanthomonadales 135614|Xanthomonadales M Glycosyl transferase waaG - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 k141_5310_1 477974.Daud_1420 2.76e-16 80.1 COG1496@1|root,COG1496@2|Bacteria,1TS34@1239|Firmicutes,248TD@186801|Clostridia,261KY@186807|Peptococcaceae 186801|Clostridia S Belongs to the multicopper oxidase YfiH RL5 family yfiH - - ko:K05810 - - - - ko00000,ko01000 - - - Cu-oxidase_4 k141_5310_2 218284.CCDN010000001_gene74 5.02e-55 172.0 COG1873@1|root,COG1873@2|Bacteria,1VEMT@1239|Firmicutes,4HNT3@91061|Bacilli,1ZI0Y@1386|Bacillus 91061|Bacilli S sporulation protein ylmC - - - - - - - - - - - PRC k141_12567_1 1116375.VEJY3_19926 1.18e-142 416.0 COG3044@1|root,COG3044@2|Bacteria,1Q603@1224|Proteobacteria,1RZ7J@1236|Gammaproteobacteria,1XUFF@135623|Vibrionales 135623|Vibrionales S ATPase of the ABC class - - - - - - - - - - - - ABC_ATPase k141_12567_2 1219076.N646_4264 5.75e-100 295.0 COG2214@1|root,COG2214@2|Bacteria,1N0S7@1224|Proteobacteria,1SAFR@1236|Gammaproteobacteria,1XTJX@135623|Vibrionales 135623|Vibrionales O COG2214 DnaJ-class molecular chaperone - - - - - - - - - - - - DNAJ_related,DnaJ k141_12567_3 1219076.N646_4263 1.24e-195 543.0 COG3491@1|root,COG3491@2|Bacteria,1MUNT@1224|Proteobacteria,1RPQ8@1236|Gammaproteobacteria,1XT0U@135623|Vibrionales 135623|Vibrionales C Belongs to the iron ascorbate-dependent oxidoreductase family - - - - - - - - - - - - 2OG-FeII_Oxy,DIOX_N k141_12567_4 223926.28809166 4.02e-129 368.0 COG3647@1|root,COG3647@2|Bacteria,1N7NB@1224|Proteobacteria,1S6G7@1236|Gammaproteobacteria,1XV3H@135623|Vibrionales 135623|Vibrionales S membrane - - - ko:K08984 - - - - ko00000 - - - DUF2238 k141_12567_5 1116375.VEJY3_19946 4.83e-65 199.0 COG1324@1|root,COG1324@2|Bacteria,1N6TN@1224|Proteobacteria,1SCFM@1236|Gammaproteobacteria,1XYEG@135623|Vibrionales 135623|Vibrionales P protein involved in tolerance to divalent cations cutA - - ko:K03926 - - - - ko00000 - - - CutA1 k141_12567_6 1219076.N646_4259 6.35e-53 166.0 2CE38@1|root,32RZ1@2|Bacteria,1N0NM@1224|Proteobacteria,1S8YZ@1236|Gammaproteobacteria,1XYBK@135623|Vibrionales 135623|Vibrionales - - VV20255 - - - - - - - - - - - - k141_12567_7 1116375.VEJY3_19956 3.52e-245 684.0 COG4533@1|root,COG4533@2|Bacteria,1N2NK@1224|Proteobacteria,1RP2Z@1236|Gammaproteobacteria,1XUBB@135623|Vibrionales 135623|Vibrionales K transport system periplasmic component sgrR - - ko:K11925 - - - - ko00000,ko03000 - - - SBP_bac_5,SgrR_N k141_8885_1 218284.CCDN010000002_gene2017 2.75e-214 603.0 COG3227@1|root,COG3227@2|Bacteria,1TP08@1239|Firmicutes,4H9S6@91061|Bacilli,1ZCEP@1386|Bacillus 91061|Bacilli E Peptidase M4 npr GO:0005575,GO:0005576 3.4.24.28 ko:K01400 - - - - ko00000,ko01000,ko01002 - - - FTP,PepSY,Peptidase_M4,Peptidase_M4_C k141_27681_2 265729.GS18_0212985 2.24e-15 77.8 28N49@1|root,2ZB9S@2|Bacteria,1UY59@1239|Firmicutes,4HBU7@91061|Bacilli,1ZG1M@1386|Bacillus 91061|Bacilli S Spore germination B3/ GerAC like, C-terminal gerKC - - - - - - - - - - - Spore_GerAC k141_24209_1 1116375.VEJY3_07280 2.49e-165 463.0 COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,1RMX5@1236|Gammaproteobacteria,1XSHS@135623|Vibrionales 135623|Vibrionales K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form cobB - - ko:K12410 - - - - ko00000,ko01000 - - - SIR2 k141_21889_1 1117647.M5M_16815 1.37e-51 181.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MWS3@1224|Proteobacteria,1RPG6@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Outer membrane receptor proteins mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec k141_20660_1 42565.FP66_14770 2.04e-104 312.0 COG3071@1|root,COG3071@2|Bacteria,1MU7A@1224|Proteobacteria,1RMRG@1236|Gammaproteobacteria,1XIR3@135619|Oceanospirillales 135619|Oceanospirillales H biosynthesis protein HemY hemY - - ko:K02498 - - - - ko00000 - - - HemY_N,TPR_7 k141_5311_1 1279017.AQYJ01000024_gene939 4.2e-94 278.0 COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,1RSY6@1236|Gammaproteobacteria,466D6@72275|Alteromonadaceae 1236|Gammaproteobacteria P Reversible hydration of carbon dioxide can GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008270,GO:0015976,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914 4.2.1.1 ko:K01673 ko00910,map00910 - R00132,R10092 RC02807 ko00000,ko00001,ko01000 - - iSBO_1134.SBO_0115,iSbBS512_1146.SbBS512_E0119 Pro_CA k141_36053_2 218284.CCDN010000001_gene216 3.04e-109 315.0 COG2963@1|root,COG2963@2|Bacteria,1V6PN@1239|Firmicutes,4HK4K@91061|Bacilli,1ZHCR@1386|Bacillus 91061|Bacilli L Helix-turn-helix domain - - - ko:K07483,ko:K09936 ko02024,map02024 - - - ko00000,ko00001,ko02000 2.A.7.21 - - HTH_28,HTH_Tnp_1,Terminase_5 k141_15913_1 443152.MDG893_02350 1.94e-20 87.4 COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,1RS3E@1236|Gammaproteobacteria,466K8@72275|Alteromonadaceae 1236|Gammaproteobacteria S LemA family lemA - - ko:K03744 - - - - ko00000 - - - LemA k141_15913_2 1453501.JELR01000001_gene1970 7.61e-76 231.0 COG4681@1|root,COG4681@2|Bacteria,1RDR9@1224|Proteobacteria,1S43N@1236|Gammaproteobacteria,466WM@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria yaeQ - - - - - - - - - - - YaeQ k141_4123_1 1049564.TevJSym_aa01140 7.67e-23 92.4 COG2062@1|root,COG2062@2|Bacteria,1N0FX@1224|Proteobacteria,1S2AY@1236|Gammaproteobacteria,1J762@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria T Phosphoglycerate mutase family sixA - - ko:K08296 - - - - ko00000,ko01000 - - - His_Phos_1 k141_4123_2 1122201.AUAZ01000002_gene1089 4.32e-29 114.0 COG4988@1|root,COG4988@2|Bacteria,1QZBS@1224|Proteobacteria,1S3K1@1236|Gammaproteobacteria 1236|Gammaproteobacteria CO ABC transporter - - - - - - - - - - - - - k141_25528_1 1042377.AFPJ01000055_gene957 1.04e-46 168.0 COG2366@1|root,COG2366@2|Bacteria,1MVMH@1224|Proteobacteria,1RMPX@1236|Gammaproteobacteria,464PP@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG2366 Protein related to penicillin acylase pvdQ - 3.5.1.97 ko:K07116 - - - - ko00000,ko01000 - - - Penicil_amidase k141_8886_1 218284.CCDN010000001_gene106 3.49e-110 321.0 COG1752@1|root,COG1752@2|Bacteria,1UUVB@1239|Firmicutes,4HDFQ@91061|Bacilli,1ZBCG@1386|Bacillus 91061|Bacilli S esterase of the alpha-beta hydrolase superfamily ylbK GO:0003674,GO:0003824,GO:0016787 - ko:K07001 - - - - ko00000 - - - Patatin k141_18415_1 218284.CCDN010000001_gene1353 1.87e-255 711.0 COG0619@1|root,COG0619@2|Bacteria,1VBW7@1239|Firmicutes,4HB6S@91061|Bacilli,1ZS19@1386|Bacillus 91061|Bacilli P Spore gernimation protein GerA gerAA_2 - - - - - - - - - - - GerA k141_30099_2 223926.28808762 1.04e-262 732.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XSE1@135623|Vibrionales 135623|Vibrionales T COG2202 FOG PAS PAC domain - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - MCPsignal,PAS_3 k141_30099_3 1348635.BBJY01000030_gene2130 4.14e-292 807.0 COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,1RPH3@1236|Gammaproteobacteria,1XUD6@135623|Vibrionales 135623|Vibrionales KT HD domain - - - - - - - - - - - - HD,HD_5 k141_30099_4 1116375.VEJY3_18451 5.83e-308 840.0 COG2041@1|root,COG2041@2|Bacteria,1MX9E@1224|Proteobacteria,1RP2M@1236|Gammaproteobacteria,1XW26@135623|Vibrionales 135623|Vibrionales S Mo-co oxidoreductase dimerisation domain - - - - - - - - - - - - Mo-co_dimer,Oxidored_molyb k141_30099_5 1116375.VEJY3_18446 1.19e-129 371.0 COG3474@1|root,COG3474@2|Bacteria,1RIDN@1224|Proteobacteria,1SI75@1236|Gammaproteobacteria,1XWMS@135623|Vibrionales 135623|Vibrionales C Cytochrome c - - - ko:K08738 ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 3.D.4.6 - - Cytochrom_C k141_30099_6 223926.28809514 4.38e-111 323.0 COG2518@1|root,COG2518@2|Bacteria 2|Bacteria O Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins - - - - - - - - - - - - Methyltransf_11,Methyltransf_25,Methyltransf_31,TPMT k141_30099_7 674977.VMC_00880 1.56e-222 620.0 COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,1RQ3D@1236|Gammaproteobacteria,1XYXH@135623|Vibrionales 135623|Vibrionales H AMP-binding enzyme - - 6.2.1.30 ko:K01912 ko00360,ko01120,ko05111,map00360,map01120,map05111 - R02539 RC00004,RC00014 ko00000,ko00001,ko01000 - - - AMP-binding,AMP-binding_C_2 k141_37259_1 1307761.L21SP2_2017 1.19e-112 338.0 COG0530@1|root,COG0530@2|Bacteria 2|Bacteria P calcium, potassium:sodium antiporter activity yrbG - - ko:K07301 - - - - ko00000,ko02000 2.A.19.5 - - Na_Ca_ex k141_37259_2 506534.Rhein_3432 8.03e-88 270.0 COG2819@1|root,COG2819@2|Bacteria,1RAB4@1224|Proteobacteria,1S2JK@1236|Gammaproteobacteria 1236|Gammaproteobacteria G hydrolase of the alpha beta superfamily Z012_06880 - - - - - - - - - - - Esterase k141_37259_3 1279017.AQYJ01000028_gene2274 4.63e-269 751.0 COG0366@1|root,COG0366@2|Bacteria,1MU90@1224|Proteobacteria,1RQ1S@1236|Gammaproteobacteria,465MB@72275|Alteromonadaceae 1236|Gammaproteobacteria G Alpha-amylase domain malS GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0004556,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009311,GO:0009313,GO:0009987,GO:0016052,GO:0016160,GO:0016787,GO:0016798,GO:0030288,GO:0030313,GO:0030978,GO:0030980,GO:0031975,GO:0042597,GO:0043167,GO:0043169,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044464,GO:0046872,GO:0051691,GO:0051692,GO:0071704,GO:1901575 3.2.1.1 ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 - R02108,R02112,R11262 - ko00000,ko00001,ko01000 - GH13 iECABU_c1320.ECABU_c40140,iECP_1309.ECP_3675,iECSE_1348.ECSE_3847,iPC815.YPO4080,ic_1306.c4392 Alpha-amylase k141_37259_4 1279017.AQYJ01000028_gene2275 1.07e-165 468.0 COG0589@1|root,COG0589@2|Bacteria,1MVZS@1224|Proteobacteria,1RPAE@1236|Gammaproteobacteria,46557@72275|Alteromonadaceae 1236|Gammaproteobacteria T Universal stress protein - - - ko:K14055 - - - - ko00000 - - - Usp k141_32456_1 1237149.C900_04490 2.32e-26 112.0 COG1629@1|root,COG4771@2|Bacteria,4NF66@976|Bacteroidetes,47JMC@768503|Cytophagia 976|Bacteroidetes P Carboxypeptidase regulatory-like domain - - - - - - - - - - - - CarboxypepD_reg,Plug,TonB_dep_Rec k141_1615_1 1279017.AQYJ01000028_gene2455 8.67e-125 364.0 COG3329@1|root,COG3329@2|Bacteria,1N85P@1224|Proteobacteria,1RRX7@1236|Gammaproteobacteria,4665S@72275|Alteromonadaceae 1236|Gammaproteobacteria S Na+-dependent bicarbonate transporter superfamily - - - ko:K07086 - - - - ko00000 - - - Sbt_1 k141_27682_1 218284.CCDN010000001_gene328 7.5e-147 429.0 COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,4HADT@91061|Bacilli,1ZAZA@1386|Bacillus 91061|Bacilli KT Transcriptional regulator - - - - - - - - - - - - HTH_8,PAS,PAS_10,PAS_9,Sigma54_activat k141_4124_1 1002809.SSIL_0690 9.64e-59 196.0 COG0726@1|root,COG3103@1|root,COG0726@2|Bacteria,COG3103@2|Bacteria,1V6DN@1239|Firmicutes,4HEPH@91061|Bacilli,26DBN@186818|Planococcaceae 91061|Bacilli G Polysaccharide deacetylase - - 3.5.1.104 ko:K22278 - - - - ko00000,ko01000 - - - DUF3298,Polysacc_deac_1 k141_6485_2 1385514.N782_04025 1.08e-12 67.4 COG0745@1|root,COG2199@1|root,COG0745@2|Bacteria,COG3706@2|Bacteria,1TSW8@1239|Firmicutes,4HBT1@91061|Bacilli,2Y943@289201|Pontibacillus 91061|Bacilli KT cheY-homologous receiver domain - - - - - - - - - - - - GGDEF,Hpt,Response_reg k141_23190_1 997296.PB1_16549 3.56e-23 97.4 COG0322@1|root,COG0322@2|Bacteria,1TP4B@1239|Firmicutes,4H9QH@91061|Bacilli,1ZBY1@1386|Bacillus 91061|Bacilli L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision uvrC - - ko:K03703 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N k141_23190_2 935836.JAEL01000016_gene279 4.43e-65 198.0 COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,4HKKX@91061|Bacilli,1ZGXM@1386|Bacillus 91061|Bacilli O Belongs to the thioredoxin family trxA GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - ko:K03671 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - Thioredoxin k141_5312_1 1453501.JELR01000001_gene2086 3.35e-36 124.0 2ETBK@1|root,33KVI@2|Bacteria,1NJFG@1224|Proteobacteria,1SHN0@1236|Gammaproteobacteria,468ZP@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_21891_1 383372.Rcas_3701 1.27e-32 132.0 COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GAAG@200795|Chloroflexi,374S4@32061|Chloroflexia 32061|Chloroflexia K transcriptional activator domain - - - - - - - - - - - - AAA_22,BTAD,TPR_12,Trans_reg_C k141_8887_1 42565.FP66_11295 1.48e-148 434.0 COG2936@1|root,COG2936@2|Bacteria,1MVA8@1224|Proteobacteria,1RN7H@1236|Gammaproteobacteria,1XM3D@135619|Oceanospirillales 135619|Oceanospirillales S Peptidase S15 - - - ko:K06978 - - - - ko00000 - - - PepX_C,Peptidase_S15 k141_11260_1 218284.CCDN010000006_gene3657 7.18e-152 444.0 COG3023@1|root,COG3023@2|Bacteria,1TR62@1239|Firmicutes,4HBJZ@91061|Bacilli,1ZFCK@1386|Bacillus 91061|Bacilli V Ami_2 - - - - - - - - - - - - Amidase_2,SLT k141_27683_1 218284.CCDN010000001_gene1938 3.34e-92 286.0 COG4987@1|root,COG4987@2|Bacteria,1UHN5@1239|Firmicutes,4HAAB@91061|Bacilli,1ZCKI@1386|Bacillus 91061|Bacilli V ATP-binding protein cydC - - ko:K16012 ko02010,map02010 - - - ko00000,ko00001,ko02000 3.A.1.129 - - ABC_membrane,ABC_tran k141_17112_1 1567010.A0A0A7S0Y0_9VIRU 8.17e-28 110.0 4QBNM@10239|Viruses 10239|Viruses S serine-type endopeptidase activity - - - - - - - - - - - - - k141_27858_1 1178482.BJB45_13930 2.58e-70 228.0 COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,1RPIW@1236|Gammaproteobacteria,1XPRY@135619|Oceanospirillales 135619|Oceanospirillales Q Amidohydrolase family - - 3.5.1.81 ko:K06015 - - R02192 RC00064,RC00328 ko00000,ko01000 - - - Amidohydro_3 k141_27858_2 1453501.JELR01000002_gene472 1.63e-84 249.0 COG0251@1|root,COG0251@2|Bacteria,1RD2M@1224|Proteobacteria,1S3V7@1236|Gammaproteobacteria,467MT@72275|Alteromonadaceae 1236|Gammaproteobacteria J Endoribonuclease L-PSP - - - - - - - - - - - - Ribonuc_L-PSP k141_27102_1 1279017.AQYJ01000029_gene3435 3.29e-122 361.0 COG1249@1|root,COG1249@2|Bacteria,1MU2Z@1224|Proteobacteria,1RMC0@1236|Gammaproteobacteria,46406@72275|Alteromonadaceae 1236|Gammaproteobacteria C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family gor GO:0000166,GO:0003674,GO:0003824,GO:0004362,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015036,GO:0015037,GO:0015038,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071949,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.7 ko:K00383 ko00480,ko04918,map00480,map04918 - R00094,R00115 RC00011 ko00000,ko00001,ko01000 - - iZ_1308.Z4900 Pyr_redox_2,Pyr_redox_dim k141_27102_2 1453501.JELR01000001_gene2635 3.39e-73 223.0 2E0SQ@1|root,32WAM@2|Bacteria,1MZWQ@1224|Proteobacteria,1S9A4@1236|Gammaproteobacteria,468C1@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_5575_1 218284.CCDN010000005_gene3228 3.83e-188 555.0 COG3857@1|root,COG3857@2|Bacteria,1TQJW@1239|Firmicutes,4HAY6@91061|Bacilli,1ZC70@1386|Bacillus 91061|Bacilli L ATP-dependent helicase deoxyribonuclease subunit B rexB GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0004527,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.6.4.12 ko:K16899 - - - - ko00000,ko01000,ko03400 - - - Exonuc_V_gamma,PDDEXK_1,UvrD_C k141_9072_1 1196031.ALEG01000032_gene5156 1.79e-42 147.0 COG0010@1|root,COG0010@2|Bacteria,1TR10@1239|Firmicutes,4HAT5@91061|Bacilli,1ZCJY@1386|Bacillus 91061|Bacilli E Belongs to the arginase family rocF GO:0003674,GO:0003824,GO:0004053,GO:0006082,GO:0006520,GO:0006525,GO:0006807,GO:0008150,GO:0008152,GO:0009064,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 3.5.3.1 ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 M00029,M00134 R00551 RC00024,RC00329 ko00000,ko00001,ko00002,ko01000 - - - Arginase k141_23434_3 1158756.AQXQ01000011_gene925 1.8e-18 93.2 COG4966@1|root,COG4966@2|Bacteria,1R5YK@1224|Proteobacteria,1RZIZ@1236|Gammaproteobacteria,1WZ5E@135613|Chromatiales 135613|Chromatiales NU Type IV Pilus-assembly protein W - - - ko:K02672 - - - - ko00000,ko02035,ko02044 - - - N_methyl,PilW k141_23434_5 1122185.N792_12990 4.8e-06 52.4 COG4970@1|root,COG4970@2|Bacteria,1QEQT@1224|Proteobacteria,1TBJ9@1236|Gammaproteobacteria,1X956@135614|Xanthomonadales 135614|Xanthomonadales NU Type II transport protein GspH - - - - - - - - - - - - GspH k141_29188_1 1116375.VEJY3_10110 2.06e-255 706.0 COG3488@1|root,COG3488@2|Bacteria,1MXUW@1224|Proteobacteria,1RRXK@1236|Gammaproteobacteria,1XTDS@135623|Vibrionales 135623|Vibrionales C Thiol oxidoreductase - - - - - - - - - - - - DHOR k141_18695_2 1347086.CCBA010000034_gene2614 7.27e-06 52.0 2BAY9@1|root,324E2@2|Bacteria,1V8TN@1239|Firmicutes,4HJ42@91061|Bacilli,1ZESD@1386|Bacillus 91061|Bacilli - - yqgU - - - - - - - - - - - - k141_14875_2 935836.JAEL01000011_gene5167 2.74e-40 134.0 COG0762@1|root,COG0762@2|Bacteria,1VEKA@1239|Firmicutes,4HNJR@91061|Bacilli,1ZHUZ@1386|Bacillus 91061|Bacilli S membrane ylmG - - ko:K02221 - - - - ko00000,ko02044 - - - YGGT k141_17303_1 997296.PB1_13774 4.02e-37 128.0 2EHDE@1|root,33B59@2|Bacteria,1VPT6@1239|Firmicutes,4HRKG@91061|Bacilli,1ZGH5@1386|Bacillus 91061|Bacilli S Inner spore coat protein D cotD - - ko:K06327 - - - - ko00000 - - - Spore-coat_CotD k141_27147_1 566466.NOR53_824 1.13e-82 271.0 COG4447@1|root,COG4447@2|Bacteria,1R6KJ@1224|Proteobacteria 1224|Proteobacteria S cellulose binding - - - - - - - - - - - - Sortilin-Vps10 k141_5604_1 1444309.JAQG01000036_gene4794 7.21e-53 181.0 COG0531@1|root,COG0531@2|Bacteria,1TT8K@1239|Firmicutes,4HCAU@91061|Bacilli,26UVT@186822|Paenibacillaceae 91061|Bacilli E amino acid yecA - - ko:K16263 - - - - ko00000,ko02000 2.A.3.13 - - AA_permease_2 k141_832_1 218284.CCDN010000001_gene270 1.15e-78 254.0 COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,4H9SP@91061|Bacilli,1ZAPS@1386|Bacillus 91061|Bacilli P COG2217 Cation transport ATPase cadA - 3.6.3.3,3.6.3.5 ko:K01534 - - - - ko00000,ko01000 3.A.3.6 - - E1-E2_ATPase,HMA,Hydrolase k141_1782_1 218284.CCDN010000007_gene3816 2.86e-113 336.0 COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,4H9Y8@91061|Bacilli,1ZBUR@1386|Bacillus 91061|Bacilli L Participates in initiation and elongation during chromosome replication dnaB GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k141_35283_2 1294265.JCM21738_4152 3.63e-14 68.6 COG3688@1|root,COG3688@2|Bacteria,1V9XR@1239|Firmicutes,4HFW4@91061|Bacilli,1ZCMG@1386|Bacillus 91061|Bacilli S RNA-binding protein containing a PIN domain yacP - - ko:K06962 - - - - ko00000 - - - NYN_YacP k141_25815_2 1279017.AQYJ01000019_gene1472 6.52e-226 624.0 COG0202@1|root,COG0202@2|Bacteria,1MU75@1224|Proteobacteria,1RMU3@1236|Gammaproteobacteria,464HA@72275|Alteromonadaceae 1236|Gammaproteobacteria K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoA GO:0003674,GO:0003824,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L k141_24489_1 1285586.H131_08328 9.18e-37 137.0 COG1680@1|root,COG1680@2|Bacteria,1TYVU@1239|Firmicutes,4HE5K@91061|Bacilli 91061|Bacilli V COG1680 Beta-lactamase class C and other penicillin binding proteins - - - - - - - - - - - - Beta-lactamase k141_22080_1 321327.CYA_0196 4.55e-43 157.0 COG0769@1|root,COG0769@2|Bacteria,1G0HH@1117|Cyanobacteria,1GZ2T@1129|Synechococcus 1117|Cyanobacteria M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan murE - 6.3.2.13 ko:K01928 ko00300,ko00550,map00300,map00550 - R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M k141_6712_1 247634.GPB2148_400 1.41e-140 428.0 COG1629@1|root,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria,1J5SG@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec k141_7754_1 935836.JAEL01000117_gene4015 1.4e-147 428.0 COG0579@1|root,COG0579@2|Bacteria,1TNZY@1239|Firmicutes,4H9PS@91061|Bacilli,1ZBRT@1386|Bacillus 91061|Bacilli S malate quinone oxidoreductase mqo - 1.1.5.4 ko:K00116 ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00009,M00011 R00360,R00361,R01257 RC00031 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS12375 Mqo k141_4254_1 69042.WH5701_04995 0.0 948.0 COG3119@1|root,COG3119@2|Bacteria,1G3QV@1117|Cyanobacteria,1GZW2@1129|Synechococcus 1117|Cyanobacteria P COG3119 Arylsulfatase A and related enzymes - - 3.1.6.1 ko:K01130 ko00140,ko00600,map00140,map00600 - R03980,R04856 RC00128,RC00231 ko00000,ko00001,ko01000 - - - Sulfatase k141_4254_2 517417.Cpar_0333 5.22e-86 272.0 COG2170@1|root,COG2170@2|Bacteria,1FEUU@1090|Chlorobi 1090|Chlorobi S ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity - - - - - - - - - - - - - k141_14009_2 1116375.VEJY3_22381 6.33e-77 244.0 COG1807@1|root,COG1807@2|Bacteria,1NMIZ@1224|Proteobacteria,1RMA2@1236|Gammaproteobacteria,1XUWV@135623|Vibrionales 135623|Vibrionales M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - - - - - - - - - - PMT k141_29189_1 218284.CCDN010000006_gene3599 1.69e-181 528.0 COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,4HAI0@91061|Bacilli,1ZAVE@1386|Bacillus 91061|Bacilli P P-type ATPase copA - 3.6.3.54 ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - - E1-E2_ATPase,HMA,Hydrolase k141_35284_1 1461580.CCAS010000008_gene1239 4.85e-99 293.0 COG1131@1|root,COG1131@2|Bacteria,1VSNZ@1239|Firmicutes,4HU0K@91061|Bacilli,1ZEUZ@1386|Bacillus 91061|Bacilli V AAA domain, putative AbiEii toxin, Type IV TA system - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_25816_1 42565.FP66_07520 1.36e-148 430.0 COG1190@1|root,COG1190@2|Bacteria,1MX1V@1224|Proteobacteria,1RMJN@1236|Gammaproteobacteria,1XITD@135619|Oceanospirillales 135619|Oceanospirillales J Belongs to the class-II aminoacyl-tRNA synthetase family lysS - 6.1.1.6 ko:K04567 ko00970,map00970 M00359,M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2,tRNA_anti-codon k141_14876_1 1122138.AQUZ01000002_gene2132 1.01e-54 195.0 COG1404@1|root,COG1404@2|Bacteria,2GK3D@201174|Actinobacteria,4DSSQ@85009|Propionibacteriales 201174|Actinobacteria O PA domain - - - - - - - - - - - - Inhibitor_I9,PA,Peptidase_S8,fn3_5 k141_12792_1 1279017.AQYJ01000020_gene1207 4.8e-229 648.0 COG0038@1|root,COG0038@2|Bacteria,1MV4K@1224|Proteobacteria,1RQJW@1236|Gammaproteobacteria,465J9@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0038 Chloride channel protein EriC eriC - - ko:K03281 - - - - ko00000 2.A.49 - - Voltage_CLC k141_9112_1 1056820.KB900640_gene278 1.05e-69 218.0 COG1075@1|root,COG1075@2|Bacteria,1P9JY@1224|Proteobacteria,1RYH4@1236|Gammaproteobacteria,2PQ8G@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria S acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - - - - - - - - - - - k141_18697_1 272558.10174842 8.94e-40 147.0 COG3345@1|root,COG3345@2|Bacteria,1TQF4@1239|Firmicutes,4HA5R@91061|Bacilli,1ZBRR@1386|Bacillus 91061|Bacilli G Alpha-galactosidase aga - 3.2.1.22 ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 - R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091 RC00049,RC00059,RC00451 ko00000,ko00001,ko01000 - - - Glyco_hydro_36C,Glyco_hydro_36N,Melibiase k141_24491_1 234267.Acid_1417 2.21e-29 115.0 COG2006@1|root,COG2006@2|Bacteria 2|Bacteria U 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - - - - - - - - - - DUF362 k141_7755_1 575589.HMPREF0018_01649 1.06e-16 81.6 COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,1RN5T@1236|Gammaproteobacteria,3NM3J@468|Moraxellaceae 1236|Gammaproteobacteria O Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen glnD GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008773,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019538,GO:0019752,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0070569,GO:0071704,GO:0140096,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.59 ko:K00990 ko02020,map02020 - - - ko00000,ko00001,ko01000 - - - ACT,GlnD_UR_UTase,HD,NTP_transf_2 k141_7755_2 1263831.F543_19350 3.23e-56 185.0 COG2171@1|root,COG2171@2|Bacteria,1MU0Y@1224|Proteobacteria,1RPCS@1236|Gammaproteobacteria,1Y6YY@135625|Pasteurellales 135625|Pasteurellales E Belongs to the transferase hexapeptide repeat family dapD - 2.3.1.117 ko:K00674 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R04365 RC00004,RC01136 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,Hexapep_2,THDPS_N_2 k141_29190_1 1196031.ALEG01000039_gene1567 4.46e-59 193.0 29ECG@1|root,301AF@2|Bacteria,1UY4W@1239|Firmicutes,4HDX6@91061|Bacilli,1ZAV2@1386|Bacillus 91061|Bacilli M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR spoIIGA GO:0003674,GO:0003824,GO:0004175,GO:0004190,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016020,GO:0016021,GO:0016787,GO:0019538,GO:0031224,GO:0031226,GO:0043170,GO:0043621,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0070001,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 - ko:K06383 - - - - ko00000,ko01000,ko01002 - - - Peptidase_U4 k141_10368_1 218284.CCDN010000002_gene2116 2.46e-263 729.0 COG0129@1|root,COG0129@2|Bacteria,1TP1R@1239|Firmicutes,4H9ZG@91061|Bacilli,1ZASK@1386|Bacillus 91061|Bacilli E Belongs to the IlvD Edd family ilvD - 4.2.1.9 ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 M00019,M00570,M00582 R01209,R04441,R05070 RC00468,RC01714 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ILVD_EDD k141_20829_1 796606.BMMGA3_01595 6.17e-148 429.0 COG0519@1|root,COG0519@2|Bacteria,1TPG8@1239|Firmicutes,4HA7Q@91061|Bacilli,1ZB6Z@1386|Bacillus 91061|Bacilli F Catalyzes the synthesis of GMP from XMP guaA GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase,GMP_synt_C,NAD_synthase k141_6713_1 218284.CCDN010000001_gene1590 4.3e-215 604.0 COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,4HAMK@91061|Bacilli,1ZBB4@1386|Bacillus 91061|Bacilli E ABC transporter substrate-binding protein dppE GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 - ko:K16199 ko02010,map02010 M00566 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.2 - - SBP_bac_5 k141_35285_1 218284.CCDN010000005_gene3424 1.49e-103 304.0 COG0702@1|root,COG0702@2|Bacteria,1TQFS@1239|Firmicutes,4HDA2@91061|Bacilli,1ZBH3@1386|Bacillus 91061|Bacilli GM NmrA-like family yhfK_2 - - - - - - - - - - - NAD_binding_10 k141_27891_2 1347369.CCAD010000074_gene3535 2.45e-30 108.0 COG2155@1|root,COG2155@2|Bacteria,1VEQJ@1239|Firmicutes,4HP56@91061|Bacilli,1ZHUV@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF378) yuzA - - ko:K09779 - - - - ko00000 - - - DUF378 k141_5605_2 218284.CCDN010000002_gene2198 8.27e-281 781.0 COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4H9ZK@91061|Bacilli,1ZDDH@1386|Bacillus 91061|Bacilli S ABC transporter - - - - - - - - - - - - ABC_tran,ABC_tran_Xtn k141_30250_1 218284.CCDN010000001_gene1073 3.04e-29 110.0 COG1388@1|root,COG1388@2|Bacteria,1V8A5@1239|Firmicutes,4HIV2@91061|Bacilli,1ZG8Q@1386|Bacillus 91061|Bacilli M Lysin motif ypbE - - - - - - - - - - - LysM k141_30250_2 997296.PB1_07372 1.26e-40 142.0 COG0671@1|root,COG0671@2|Bacteria,1V33Y@1239|Firmicutes,4HGAT@91061|Bacilli,1ZFPM@1386|Bacillus 91061|Bacilli I COG0671 Membrane-associated phospholipid phosphatase pgpB1 - 3.6.1.27 ko:K19302 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - PAP2 k141_36213_1 400668.Mmwyl1_3138 2.34e-67 214.0 COG0179@1|root,COG0179@2|Bacteria,1MV0V@1224|Proteobacteria,1RNYV@1236|Gammaproteobacteria,1XH60@135619|Oceanospirillales 135619|Oceanospirillales Q Fumarylacetoacetate (FAA) hydrolase - - 3.7.1.2 ko:K16171 ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120 M00044 R01364 RC00326,RC00446 ko00000,ko00001,ko00002,ko01000 - - - FAA_hydrolase k141_36213_2 1504981.KO116_4310 6.32e-104 304.0 COG3837@1|root,COG3837@2|Bacteria,1QWY0@1224|Proteobacteria,1T2Z8@1236|Gammaproteobacteria,1XN0I@135619|Oceanospirillales 135619|Oceanospirillales S PFAM Cupin 2, conserved barrel - - - - - - - - - - - - Cupin_2 k141_36213_3 400668.Mmwyl1_3140 1.35e-190 537.0 COG0654@1|root,COG0654@2|Bacteria,1MWWT@1224|Proteobacteria,1S0S0@1236|Gammaproteobacteria 1236|Gammaproteobacteria CH FAD binding domain - - 1.14.13.218 ko:K20940 ko00405,ko01130,map00405,map01130 M00835 - - ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_3 k141_14010_1 1034347.CAHJ01000062_gene977 1.33e-121 362.0 COG0277@1|root,COG0277@2|Bacteria,1TQMR@1239|Firmicutes,4HDHV@91061|Bacilli,1ZEDC@1386|Bacillus 91061|Bacilli C FAD binding domain - - - ko:K11472 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001 - - - FAD-oxidase_C,FAD_binding_4 k141_9114_1 42565.FP66_10515 1.3e-110 332.0 28WQX@1|root,2ZIQM@2|Bacteria 2|Bacteria S HlyD family secretion protein - - 2.4.1.33 ko:K19291 ko00051,ko02025,map00051,map02025 - R08692 RC00005 ko00000,ko00001,ko01000 - - - HlyD_3,PilZ k141_1784_1 218284.CCDN010000001_gene1592 3.63e-103 306.0 COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4H9PZ@91061|Bacilli,1ZC9B@1386|Bacillus 91061|Bacilli EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components dppC - - ko:K16201 ko02010,map02010 M00566 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.2 - - BPD_transp_1,OppC_N k141_24492_1 218284.CCDN010000005_gene3477 1.05e-165 473.0 COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,4H9VI@91061|Bacilli,1ZB6B@1386|Bacillus 91061|Bacilli G Belongs to the GPI family pgi GO:0003674,GO:0003824,GO:0004347,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGI k141_35286_1 1340434.AXVA01000005_gene4850 5.66e-87 272.0 COG4626@1|root,COG4626@2|Bacteria,1TPU1@1239|Firmicutes,4HAXI@91061|Bacilli,1ZE32@1386|Bacillus 91061|Bacilli S Terminase - - - - - - - - - - - - Terminase_1 k141_29191_1 218284.CCDN010000001_gene946 2.59e-160 473.0 COG0209@1|root,COG0209@2|Bacteria,1TPFH@1239|Firmicutes,4HA07@91061|Bacilli,1ZCST@1386|Bacillus 91061|Bacilli F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen nrdZ - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_lgC,Ribonuc_red_lgN k141_7756_2 796606.BMMGA3_06410 1.22e-17 76.3 2DR6C@1|root,33ACS@2|Bacteria,1VM75@1239|Firmicutes,4HR6M@91061|Bacilli,1ZJYN@1386|Bacillus 91061|Bacilli S YlzJ-like protein - - - - - - - - - - - - YlzJ k141_4256_1 1211814.CAPG01000059_gene2882 4.55e-12 67.0 29H5Q@1|root,30439@2|Bacteria,1V63Q@1239|Firmicutes,4HHR2@91061|Bacilli,1ZE9T@1386|Bacillus 91061|Bacilli S Nuclease-related domain - - - - - - - - - - - - NERD k141_6714_1 395019.Bmul_4794 2.86e-12 62.8 COG1917@1|root,COG1917@2|Bacteria,1RH1V@1224|Proteobacteria,2VVK1@28216|Betaproteobacteria,1K83W@119060|Burkholderiaceae 28216|Betaproteobacteria S Cupin domain - - - - - - - - - - - - Cupin_2 k141_6714_2 1515746.HR45_03800 2.65e-36 129.0 COG4925@1|root,COG4925@2|Bacteria,1N8YU@1224|Proteobacteria,1SDSQ@1236|Gammaproteobacteria,2QCYE@267890|Shewanellaceae 1236|Gammaproteobacteria I sulfurtransferase activity - - - - - - - - - - - - Cyclophil_like k141_35287_1 1453501.JELR01000002_gene339 1.15e-98 306.0 COG1629@1|root,COG4771@2|Bacteria,1MUPZ@1224|Proteobacteria,1RMMP@1236|Gammaproteobacteria,464D4@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport acr - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_9115_1 218284.CCDN010000001_gene1744 1.1e-100 302.0 COG0350@1|root,COG2169@1|root,COG0350@2|Bacteria,COG2169@2|Bacteria,1VA03@1239|Firmicutes,4HBU4@91061|Bacilli,1ZD6K@1386|Bacillus 91061|Bacilli F Metal binding domain of Ada ada - 2.1.1.63 ko:K10778 - - - - ko00000,ko01000,ko03000,ko03400 - - - Ada_Zn_binding,DNA_binding_1,HTH_18,Methyltransf_1N k141_18701_1 1042377.AFPJ01000055_gene972 3.54e-43 160.0 COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,1MVI9@1224|Proteobacteria,1RNB0@1236|Gammaproteobacteria,4649B@72275|Alteromonadaceae 1236|Gammaproteobacteria D COG0489 ATPases involved in chromosome partitioning - - - ko:K16554 ko05111,map05111 - - - ko00000,ko00001,ko02000 8.A.3.1 - - AAA_31,CbiA,GNVR,Wzz k141_29192_1 1294265.JCM21738_1818 1.51e-164 472.0 COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HB3V@91061|Bacilli,1ZB8V@1386|Bacillus 91061|Bacilli IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II alkK - - ko:K00666 - - - - ko00000,ko01000,ko01004 - - - AMP-binding,AMP-binding_C k141_36214_1 1294265.JCM21738_3650 1.52e-57 189.0 COG2208@1|root,COG2208@2|Bacteria,1TQ92@1239|Firmicutes,4HB0X@91061|Bacilli,1ZMIF@1386|Bacillus 91061|Bacilli KT stage II sporulation protein E spoIIE GO:0005575,GO:0005623,GO:0042601,GO:0042763,GO:0044464 3.1.3.16 ko:K06382 - - - - ko00000,ko01000 - - - SpoIIE k141_6715_1 1453501.JELR01000001_gene2027 3.42e-42 149.0 COG0174@1|root,COG0174@2|Bacteria,1MU6V@1224|Proteobacteria,1RPNZ@1236|Gammaproteobacteria,465I0@72275|Alteromonadaceae 1236|Gammaproteobacteria E Glutamine synthetase, catalytic domain - - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C k141_25819_2 1279017.AQYJ01000021_gene2877 2.04e-181 531.0 COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,1RMA7@1236|Gammaproteobacteria,465DP@72275|Alteromonadaceae 1236|Gammaproteobacteria E aminopeptidase N pepN GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0009056,GO:0009987,GO:0016020,GO:0016787,GO:0019538,GO:0033218,GO:0034641,GO:0042277,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - iECIAI1_1343.ECIAI1_0973,iECO103_1326.ECO103_0977,iECP_1309.ECP_0944,iECSE_1348.ECSE_0993,iECW_1372.ECW_m1042,iEKO11_1354.EKO11_2898,iWFL_1372.ECW_m1042 DUF3458,DUF3458_C,Peptidase_M1 k141_22086_1 218284.CCDN010000002_gene2737 1.85e-111 332.0 COG0019@1|root,COG0019@2|Bacteria,1TPE9@1239|Firmicutes,4H9XW@91061|Bacilli,1ZD43@1386|Bacillus 91061|Bacilli E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine lysA - 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N,Orn_DAP_Arg_deC k141_24495_2 1453501.JELR01000002_gene726 5.52e-52 173.0 COG2378@1|root,COG2378@2|Bacteria,1PXCX@1224|Proteobacteria,1RR3V@1236|Gammaproteobacteria,466P3@72275|Alteromonadaceae 1236|Gammaproteobacteria K WYL domain - - - - - - - - - - - - HTH_11,WYL k141_27164_1 477974.Daud_0871 1.03e-27 113.0 COG1614@1|root,COG1614@2|Bacteria,1TSWZ@1239|Firmicutes,248Y2@186801|Clostridia,2618Z@186807|Peptococcaceae 186801|Clostridia C PFAM CO dehydrogenase acetyl-CoA synthase complex beta subunit cdhC - 2.3.1.169 ko:K14138 ko00720,ko01120,ko01200,map00720,map01120,map01200 M00377 R08433,R10243 RC00004,RC00113,RC01144,RC02963,RC02964,RC02977 ko00000,ko00001,ko00002,ko01000 - - - CdhC k141_14037_2 1408303.JNJJ01000033_gene2532 6.15e-47 155.0 COG1595@1|root,COG1595@2|Bacteria,1V4T2@1239|Firmicutes,4HFZ0@91061|Bacilli,1ZEC7@1386|Bacillus 91061|Bacilli K Belongs to the sigma-70 factor family. ECF subfamily sigX GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4,Sigma70_r4_2 k141_12806_2 1279017.AQYJ01000026_gene306 9.51e-254 716.0 COG2274@1|root,COG2274@2|Bacteria,1R2T0@1224|Proteobacteria,1SBE1@1236|Gammaproteobacteria,464I6@72275|Alteromonadaceae 1236|Gammaproteobacteria V COG2274 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain cvaB - - ko:K06147,ko:K13409 ko02010,ko04626,map02010,map04626 M00339 - - ko00000,ko00001,ko00002,ko02000,ko02044 3.A.1.106,3.A.1.109,3.A.1.110,3.A.1.21 - - ABC_membrane,ABC_tran,Peptidase_C39,cNMP_binding k141_36235_2 1307436.PBF_00485 1.81e-19 85.9 COG0785@1|root,COG0785@2|Bacteria,1TQH1@1239|Firmicutes,4H9UJ@91061|Bacilli,1ZBPX@1386|Bacillus 91061|Bacilli O cytochrome c biogenesis protein ccdA - - ko:K06196 - - - - ko00000,ko02000 5.A.1.2 - - DsbD k141_18729_1 1499683.CCFF01000014_gene4080 0.000476 48.1 COG0477@1|root,COG2814@2|Bacteria,1UZPE@1239|Firmicutes,2490R@186801|Clostridia,36EGS@31979|Clostridiaceae 186801|Clostridia EGP PFAM Major Facilitator Superfamily - - - - - - - - - - - - MFS_1,MFS_3 k141_24533_1 566466.NOR53_2152 1.79e-101 309.0 28I8B@1|root,2Z8B5@2|Bacteria,1MUNM@1224|Proteobacteria,1RQ1H@1236|Gammaproteobacteria,1J4H2@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Cytochrome c bacterial - - - - - - - - - - - - Cytochrome_C554,Cytochrome_cB k141_1804_1 218284.CCDN010000001_gene89 2.08e-100 309.0 COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,4H9VQ@91061|Bacilli,1ZBC0@1386|Bacillus 91061|Bacilli M stage V sporulation protein D spoVD - - ko:K08384 ko00550,map00550 - - - ko00000,ko00001,ko01011 - - - PASTA,PBP_dimer,Transpeptidase k141_4276_1 861299.J421_2790 3.45e-10 58.9 COG0256@1|root,COG0256@2|Bacteria,1ZTUX@142182|Gemmatimonadetes 142182|Gemmatimonadetes J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance rplR - - ko:K02881 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L18p k141_4276_2 649764.HMPREF0762_01819 5.27e-65 204.0 COG0097@1|root,COG0097@2|Bacteria,2GK35@201174|Actinobacteria,4CVIK@84998|Coriobacteriia 84998|Coriobacteriia J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center rplF - - ko:K02933 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L6 k141_4276_3 97138.C820_00859 2e-17 76.6 COG0096@1|root,COG0096@2|Bacteria,1V3KK@1239|Firmicutes,24HCP@186801|Clostridia,36I6W@31979|Clostridiaceae 186801|Clostridia J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit rpsH - - ko:K02994 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S8 k141_14912_1 42565.FP66_02540 7.05e-11 60.1 COG0711@1|root,COG0711@2|Bacteria,1RHZ0@1224|Proteobacteria,1S402@1236|Gammaproteobacteria,1XJMN@135619|Oceanospirillales 135619|Oceanospirillales C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) atpF - - ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_B k141_14912_2 42565.FP66_02535 5.21e-118 338.0 COG0712@1|root,COG0712@2|Bacteria,1MVRH@1224|Proteobacteria,1S8X2@1236|Gammaproteobacteria,1XK2G@135619|Oceanospirillales 135619|Oceanospirillales C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpH - - ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - OSCP k141_14912_3 42565.FP66_02530 4.66e-78 246.0 COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,1RP4V@1236|Gammaproteobacteria,1XHRG@135619|Oceanospirillales 135619|Oceanospirillales C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit atpA - 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N k141_32701_1 1453501.JELR01000002_gene144 7.59e-58 181.0 COG0799@1|root,COG0799@2|Bacteria,1MZEF@1224|Proteobacteria,1S8W3@1236|Gammaproteobacteria,467TU@72275|Alteromonadaceae 1236|Gammaproteobacteria J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation rsfS GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113 - ko:K09710 - - - - ko00000,ko03009 - - - RsfS k141_32701_2 1453501.JELR01000002_gene143 1.87e-94 277.0 COG1576@1|root,COG1576@2|Bacteria,1R9Z2@1224|Proteobacteria,1S1ZY@1236|Gammaproteobacteria,466GK@72275|Alteromonadaceae 1236|Gammaproteobacteria J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA rlmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042802,GO:0042803,GO:0043021,GO:0043022,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0044877,GO:0046483,GO:0046983,GO:0070037,GO:0070038,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.177 ko:K00783 - - - - ko00000,ko01000,ko03009 - - - SPOUT_MTase k141_22111_1 1453501.JELR01000001_gene2455 5.81e-20 86.3 COG2513@1|root,COG2513@2|Bacteria,1N4VT@1224|Proteobacteria,1RMR5@1236|Gammaproteobacteria,464GF@72275|Alteromonadaceae 1236|Gammaproteobacteria G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate prpB GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006113,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0015980,GO:0016042,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019752,GO:0032787,GO:0042737,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0046421,GO:0046459,GO:0046872,GO:0055114,GO:0071704,GO:0072329,GO:1901575 4.1.3.30 ko:K03417 ko00640,map00640 - R00409 RC00286,RC00287 ko00000,ko00001,ko01000 - - iECNA114_1301.ECNA114_0319,iECP_1309.ECP_0407 PEP_mutase k141_22111_2 1279017.AQYJ01000025_gene643 2.26e-53 177.0 COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,1RNT1@1236|Gammaproteobacteria,465RE@72275|Alteromonadaceae 1236|Gammaproteobacteria C Belongs to the citrate synthase family prpC GO:0003674,GO:0003824,GO:0004108,GO:0006082,GO:0006091,GO:0006113,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016740,GO:0016746,GO:0016829,GO:0016830,GO:0016833,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0036440,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0046459,GO:0046912,GO:0050440,GO:0055114,GO:0071704 2.3.3.5 ko:K01659 ko00640,map00640 - R00931 RC00004,RC00406,RC02827 ko00000,ko00001,ko01000 - - iECED1_1282.ECED1_0365,iECIAI1_1343.ECIAI1_0334,iECIAI39_1322.ECIAI39_0347,iECP_1309.ECP_0408,iECSF_1327.ECSF_0308,iEcE24377_1341.EcE24377A_0357,iJN746.PP_2335,iLF82_1304.LF82_1740,iNRG857_1313.NRG857_01630 Citrate_synt k141_3011_1 935837.JAEK01000034_gene3028 1.59e-89 268.0 COG0454@1|root,COG0456@2|Bacteria,1U521@1239|Firmicutes,4HBEJ@91061|Bacilli,1ZCHR@1386|Bacillus 91061|Bacilli K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases ykwB - - - - - - - - - - - Acetyltransf_1 k141_37457_1 1453501.JELR01000002_gene690 2.74e-99 305.0 COG0471@1|root,COG0569@1|root,COG0471@2|Bacteria,COG0569@2|Bacteria,1MU0K@1224|Proteobacteria,1RMI1@1236|Gammaproteobacteria,464A6@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0471 Di- and tricarboxylate transporters - - - - - - - - - - - - CitMHS,TrkA_C k141_12808_1 218284.CCDN010000002_gene2734 2.43e-116 340.0 COG0697@1|root,COG0697@2|Bacteria,1TP9B@1239|Firmicutes,4H9TT@91061|Bacilli,1ZB35@1386|Bacillus 91061|Bacilli EG Putative multidrug resistance efflux transporter yjlA - - - - - - - - - - - EmrE k141_36236_2 1294265.JCM21738_2662 1.94e-112 330.0 COG2267@1|root,COG2267@2|Bacteria,1TSC4@1239|Firmicutes,4HBYX@91061|Bacilli,1ZEAA@1386|Bacillus 91061|Bacilli I hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - - - - - - - - - - Abhydrolase_1,Hydrolase_4 k141_14914_1 1385514.N782_05045 1.53e-41 144.0 COG2267@1|root,COG2267@2|Bacteria,1UIIF@1239|Firmicutes,4HHJE@91061|Bacilli,2YBAZ@289201|Pontibacillus 91061|Bacilli I alpha/beta hydrolase fold - - - - - - - - - - - - Abhydrolase_6 k141_1976_2 1227360.C176_09097 4.39e-17 82.4 COG0454@1|root,COG1357@1|root,COG0456@2|Bacteria,COG1357@2|Bacteria,1V5QZ@1239|Firmicutes,4HIE3@91061|Bacilli 91061|Bacilli K Pentapeptide repeats (8 copies) - - - - - - - - - - - - Acetyltransf_10,Acetyltransf_7,Pentapeptide,Pentapeptide_4 k141_36420_1 1500893.JQNB01000001_gene2221 3.27e-44 163.0 COG1629@1|root,COG4771@2|Bacteria,1MW4X@1224|Proteobacteria,1RPVY@1236|Gammaproteobacteria,1X3CF@135614|Xanthomonadales 135614|Xanthomonadales P Outer membrane receptor for ferrienterochelin and colicins - - - - - - - - - - - - CarboxypepD_reg,Plug,TonB_dep_Rec k141_4425_1 751994.AGIG01000028_gene1582 9.79e-15 79.0 COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,1RN9H@1236|Gammaproteobacteria,1J4EU@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Catalyzes cross-linking of the peptidoglycan cell wall mrdA GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0045229,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 3.4.16.4 ko:K05515 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - iEcE24377_1341.EcE24377A_0661,iPC815.YPO2604 PBP_dimer,Transpeptidase k141_5795_1 1116472.MGMO_174c00290 4.84e-29 121.0 COG0457@1|root,COG0457@2|Bacteria,1R50I@1224|Proteobacteria,1RSP6@1236|Gammaproteobacteria,1XG0P@135618|Methylococcales 135618|Methylococcales S Tetratricopeptide repeat - - - - - - - - - - - - - k141_22452_1 1347369.CCAD010000056_gene4349 4.63e-87 270.0 28PT3@1|root,2ZCEG@2|Bacteria,1V3FJ@1239|Firmicutes,4HG7M@91061|Bacilli,1ZFCJ@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF4179) - - - - - - - - - - - - DUF4179 k141_20996_1 1379698.RBG1_1C00001G1850 1.78e-69 222.0 COG0705@1|root,COG0705@2|Bacteria,2NPSK@2323|unclassified Bacteria 2|Bacteria S Rhomboid family - - - - - - - - - - - - Rhomboid k141_7066_1 393283.XP_007838838.1 6.91e-38 147.0 COG0143@1|root,KOG4135@1|root,KOG0436@2759|Eukaryota,KOG4135@2759|Eukaryota,38HBR@33154|Opisthokonta,3NWSF@4751|Fungi,3QMZ2@4890|Ascomycota,215Z0@147550|Sordariomycetes 4751|Fungi J Belongs to the class-I aminoacyl-tRNA synthetase family MSM1 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031974,GO:0032543,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140053,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Acetyltransf_3,tRNA-synt_1g k141_11833_1 1499685.CCFJ01000012_gene1766 1.26e-05 46.2 COG2197@1|root,COG2197@2|Bacteria,1TRXG@1239|Firmicutes,4HHIC@91061|Bacilli,1ZC3A@1386|Bacillus 91061|Bacilli KT LuxR family transcriptional regulator - - - - - - - - - - - - GerE,Response_reg k141_10497_2 1453501.JELR01000002_gene572 2.37e-130 381.0 2BXSN@1|root,32R1X@2|Bacteria,1MYVK@1224|Proteobacteria,1S821@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF4243) - - - - - - - - - - - - DUF4243 k141_10497_3 1121937.AUHJ01000005_gene2326 7.76e-140 412.0 2C7MP@1|root,2Z7Q4@2|Bacteria,1NHK1@1224|Proteobacteria,1RQ17@1236|Gammaproteobacteria,466D3@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0500 SAM-dependent methyltransferases PP0279 - - - - - - - - - - - Methyltransf_32 k141_20076_1 1042377.AFPJ01000004_gene349 3.43e-91 278.0 COG3468@1|root,COG3468@2|Bacteria,1NTR4@1224|Proteobacteria,1T238@1236|Gammaproteobacteria,465K5@72275|Alteromonadaceae 1236|Gammaproteobacteria MU Protein of unknown function (DUF3014) - - - - - - - - - - - - DUF3014 k141_5833_1 666686.B1NLA3E_06620 9.52e-53 169.0 COG0779@1|root,COG0779@2|Bacteria,1V6KT@1239|Firmicutes,4HH88@91061|Bacilli,1ZG6S@1386|Bacillus 91061|Bacilli S Required for maturation of 30S ribosomal subunits rimP GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - ko:K09748 - - - - ko00000,ko03009 - - - DUF150,DUF150_C k141_5833_2 1347086.CCBA010000030_gene41 3.82e-18 82.4 COG0195@1|root,COG0195@2|Bacteria,1TPB3@1239|Firmicutes,4HA7F@91061|Bacilli,1ZDAH@1386|Bacillus 91061|Bacilli K Participates in both transcription termination and antitermination nusA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K02600 - - - - ko00000,ko03009,ko03021 - - - KH_5,NusA_N,S1 k141_22496_1 1453501.JELR01000001_gene1805 1.01e-128 375.0 COG0208@1|root,COG0208@2|Bacteria,1MWUS@1224|Proteobacteria,1RMJC@1236|Gammaproteobacteria,4649Z@72275|Alteromonadaceae 1236|Gammaproteobacteria F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdB - 1.17.4.1 ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - iJN746.PP_1177 Ribonuc_red_sm k141_35560_1 1042377.AFPJ01000024_gene741 2.49e-112 337.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPWS@1236|Gammaproteobacteria,464W9@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0488 ATPase components of ABC transporters with duplicated ATPase domains yjjK GO:0003674,GO:0003824,GO:0005488,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:2000112,GO:2000113 3.6.3.25 ko:K06020 - - - - ko00000,ko01000 - - - ABC_tran,ABC_tran_Xtn k141_22497_1 198467.NP92_01970 8.65e-110 321.0 COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4H9WY@91061|Bacilli,21WEP@150247|Anoxybacillus 91061|Bacilli E ATPases associated with a variety of cellular activities - - 3.6.3.21 ko:K02028 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran k141_30422_1 218284.CCDN010000001_gene607 1.62e-124 362.0 COG2334@1|root,COG2334@2|Bacteria,1V54J@1239|Firmicutes,4HH2K@91061|Bacilli,1ZB97@1386|Bacillus 91061|Bacilli S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response ysxE - - - - - - - - - - - APH k141_7122_1 1526927.Plano_1448 5.46e-11 63.9 COG0477@1|root,COG2814@2|Bacteria,1UXXX@1239|Firmicutes,4HC83@91061|Bacilli,26GPY@186818|Planococcaceae 91061|Bacilli EGP Sugar (and other) transporter - - - - - - - - - - - - MFS_1,Sugar_tr k141_26100_1 1294265.JCM21738_2504 1.77e-102 303.0 COG0760@1|root,COG0760@2|Bacteria,1V2D1@1239|Firmicutes,4HFU5@91061|Bacilli,1ZRKY@1386|Bacillus 91061|Bacilli O Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins prsA - 5.2.1.8 ko:K07533 - - - - ko00000,ko01000,ko03110 - - - Rotamase_2,Rotamase_3,SurA_N_3 k141_34270_2 1453501.JELR01000002_gene177 7.6e-31 119.0 COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,1RNQ8@1236|Gammaproteobacteria,463YI@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) hemA GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006536,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008883,GO:0009058,GO:0009064,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019353,GO:0019438,GO:0019752,GO:0033013,GO:0033014,GO:0033526,GO:0034641,GO:0042168,GO:0042440,GO:0042802,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.2.1.70 ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R04109 RC00055,RC00149 ko00000,ko00001,ko00002,ko01000 - - iECNA114_1301.ECNA114_1375,iECSF_1327.ECSF_1186,iUTI89_1310.UTI89_C1404 GlutR_N,GlutR_dimer,Shikimate_DH k141_16403_1 1453501.JELR01000001_gene2955 3.64e-37 134.0 COG0204@1|root,COG0204@2|Bacteria,1MUFH@1224|Proteobacteria,1RNJQ@1236|Gammaproteobacteria,465A9@72275|Alteromonadaceae 1236|Gammaproteobacteria I Phosphate acyltransferases - - - - - - - - - - - - Acyltransferase k141_4463_1 218284.CCDN010000006_gene3711 5.4e-105 322.0 COG0737@1|root,COG0737@2|Bacteria,1TPV2@1239|Firmicutes,4HB9S@91061|Bacilli,1ZAY0@1386|Bacillus 91061|Bacilli F Belongs to the 5'-nucleotidase family cpdB - 3.1.3.5,3.1.3.6,3.1.4.16,3.6.1.45 ko:K01081,ko:K01119,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01562,R01569,R01664,R01877,R01968,R02088,R02102,R02148,R02323,R02370,R02719,R03346,R03537,R03538,R03929,R05135 RC00017,RC00078,RC00296 ko00000,ko00001,ko01000 - - - 5_nucleotid_C,Gram_pos_anchor,LysM,Metallophos,SNase k141_17472_1 1453501.JELR01000002_gene1169 9.67e-104 315.0 COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,1RSH1@1236|Gammaproteobacteria,465PI@72275|Alteromonadaceae 1236|Gammaproteobacteria O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions - - - ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 - - - Cpn60_TCP1 k141_11852_2 1279017.AQYJ01000027_gene1843 7.31e-46 151.0 COG2259@1|root,COG2259@2|Bacteria,1MZVP@1224|Proteobacteria,1S8UI@1236|Gammaproteobacteria,46C89@72275|Alteromonadaceae 1236|Gammaproteobacteria S DoxX - - - ko:K15977 - - - - ko00000 - - - DoxX k141_11852_7 1279017.AQYJ01000027_gene1838 2.41e-156 443.0 COG0235@1|root,COG0235@2|Bacteria,1MWP9@1224|Proteobacteria,1RQNI@1236|Gammaproteobacteria,466NS@72275|Alteromonadaceae 1236|Gammaproteobacteria G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases - - - - - - - - - - - - Aldolase_II k141_20077_2 218284.CCDN010000003_gene3009 2.89e-191 541.0 COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,4HB31@91061|Bacilli,1ZARE@1386|Bacillus 91061|Bacilli EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia pabB GO:0000162,GO:0000287,GO:0003674,GO:0003824,GO:0004049,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006575,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009108,GO:0009308,GO:0009309,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042398,GO:0042401,GO:0042430,GO:0042435,GO:0042558,GO:0042559,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 2.6.1.85 ko:K01665 ko00790,map00790 - R01716 RC00010,RC01418 ko00000,ko00001,ko01000 - - - Anth_synt_I_N,Chorismate_bind k141_10499_1 1124991.MU9_1486 2.93e-47 164.0 COG0131@1|root,COG0241@1|root,COG0131@2|Bacteria,COG0241@2|Bacteria,1MWBS@1224|Proteobacteria,1RPA9@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Histidine biosynthesis bifunctional protein HisB hisB GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0004424,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042578,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.15,4.2.1.19 ko:K01089,ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R03013,R03457 RC00017,RC00932 ko00000,ko00001,ko00002,ko01000 - - iECO111_1330.ECO111_2746,iECS88_1305.ECS88_2121,iJN746.PP_0289,iUMNK88_1353.UMNK88_2570 Hydrolase_like,IGPD,PNK3P k141_17473_1 1453501.JELR01000001_gene3150 8.05e-85 263.0 COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,1RQ8B@1236|Gammaproteobacteria,465GI@72275|Alteromonadaceae 1236|Gammaproteobacteria T His Kinase A (phosphoacceptor) domain styS - - - - - - - - - - - HATPase_c,PAS_8 k141_7123_1 1274524.BSONL12_10421 4.98e-140 412.0 COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,4HBZI@91061|Bacilli,1ZFAF@1386|Bacillus 91061|Bacilli E Bacterial extracellular solute-binding proteins, family 5 Middle nikA - - ko:K15584 ko02010,map02010 M00440 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 k141_28096_1 1450694.BTS2_2568 1.37e-10 65.5 2DMBQ@1|root,32HI1@2|Bacteria,1VHXM@1239|Firmicutes,4IT0Q@91061|Bacilli,1ZSIF@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - LppX_LprAFG k141_26101_1 1453501.JELR01000002_gene60 3.55e-67 211.0 COG0583@1|root,COG0583@2|Bacteria,1MUWX@1224|Proteobacteria,1RMVV@1236|Gammaproteobacteria,466MX@72275|Alteromonadaceae 1236|Gammaproteobacteria K Transcriptional regulator - - - ko:K17737 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate k141_17474_1 218284.CCDN010000001_gene1668 3.57e-111 342.0 COG3973@1|root,COG3973@2|Bacteria,1TP39@1239|Firmicutes,4H9Y5@91061|Bacilli,1ZAWP@1386|Bacillus 91061|Bacilli L DNA helicase uvrD - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_19,UvrD-helicase,UvrD_C,UvrD_C_2 k141_7124_1 218284.CCDN010000001_gene1244 8.24e-80 249.0 COG0534@1|root,COG0534@2|Bacteria,1TP5U@1239|Firmicutes,4HA4W@91061|Bacilli,1ZAX6@1386|Bacillus 91061|Bacilli V Multidrug efflux pump norM GO:0003674,GO:0005215,GO:0006810,GO:0006855,GO:0008150,GO:0015238,GO:0015893,GO:0022857,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0046677,GO:0050896,GO:0051179,GO:0051234,GO:0055085 - ko:K03327 - - - - ko00000,ko02000 2.A.66.1 - - MatE k141_7124_2 218284.CCDN010000001_gene1243 3.49e-43 147.0 COG1028@1|root,COG1028@2|Bacteria,1TSQV@1239|Firmicutes,4HB3U@91061|Bacilli,1ZC75@1386|Bacillus 91061|Bacilli IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) ytkK - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 k141_15137_1 1250278.JQNQ01000001_gene330 1.42e-08 58.5 COG2342@1|root,COG2342@2|Bacteria,4NH17@976|Bacteroidetes,1I03F@117743|Flavobacteriia 976|Bacteroidetes G Glycoside-hydrolase family GH114 - - 6.1.1.16 ko:K01884 ko00970,map00970 M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Glyco_hydro_114 k141_15137_2 1415754.JQMK01000012_gene997 5.97e-11 57.8 2BFPN@1|root,329I7@2|Bacteria,1QNMJ@1224|Proteobacteria,1SHZF@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF3096) - - - - - - - - - - - - DUF3096 k141_21032_2 218284.CCDN010000001_gene984 3.71e-180 511.0 COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,4H9Z5@91061|Bacilli,1ZBCS@1386|Bacillus 91061|Bacilli C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes bfmBC - 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyr_redox_2,Pyr_redox_dim k141_17475_1 218284.CCDN010000004_gene3059 8.41e-153 436.0 COG0772@1|root,COG0772@2|Bacteria,1TPGH@1239|Firmicutes,4HAV4@91061|Bacilli,1ZBSB@1386|Bacillus 91061|Bacilli D Belongs to the SEDS family rodA - - ko:K05837 - - - - ko00000,ko03036 - - - FTSW_RODA_SPOVE k141_37675_1 1453501.JELR01000005_gene1616 1.11e-163 480.0 COG3391@1|root,COG3391@2|Bacteria,1RA6R@1224|Proteobacteria,1SE8J@1236|Gammaproteobacteria 1236|Gammaproteobacteria S amine dehydrogenase activity - - - - - - - - - - - - - k141_4466_1 1382305.AZUC01000049_gene1599 7.52e-39 139.0 COG1708@1|root,COG1708@2|Bacteria,1VXEG@1239|Firmicutes,4HXJA@91061|Bacilli 91061|Bacilli S Streptomycin adenylyltransferase - - - - - - - - - - - - Adenyl_transf k141_31584_1 997296.PB1_15549 2.35e-68 216.0 COG0482@1|root,COG0482@2|Bacteria,1TPIZ@1239|Firmicutes,4HBJ6@91061|Bacilli,1ZBWQ@1386|Bacillus 91061|Bacilli J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 mnmA GO:0002097,GO:0002098,GO:0002143,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 2.8.1.13 ko:K00566 ko04122,map04122 - R08700 RC02313,RC02315 ko00000,ko00001,ko01000,ko03016 - - - tRNA_Me_trans k141_31584_2 1294265.JCM21738_5074 1.7e-131 381.0 COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,4HA6H@91061|Bacilli,1ZB1B@1386|Bacillus 91061|Bacilli E Cysteine desulfurase iscS - 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - - Aminotran_5 k141_20081_1 218284.CCDN010000008_gene4130 5.02e-118 376.0 COG0366@1|root,COG1523@1|root,COG5492@1|root,COG0366@2|Bacteria,COG1523@2|Bacteria,COG5492@2|Bacteria,1TP3M@1239|Firmicutes,4HBP5@91061|Bacilli,1ZC85@1386|Bacillus 91061|Bacilli G Belongs to the glycosyl hydrolase 13 family pulA2 - 3.2.1.1,3.2.1.41 ko:K01176,ko:K01200 ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973 - R02108,R02111,R02112,R11262 - ko00000,ko00001,ko01000 - CBM48,GH13 - Alpha-amylase,Big_2,CBM_48,G5,Gram_pos_anchor,PUD,SLH,YSIRK_signal k141_10501_1 1033734.CAET01000075_gene2778 9.3e-47 155.0 2DN7T@1|root,32W0M@2|Bacteria,1VCUR@1239|Firmicutes,4HKRJ@91061|Bacilli,1ZIP8@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_3274_1 1479239.JQMU01000001_gene2230 1.41e-69 244.0 COG1629@1|root,COG1629@2|Bacteria,1N7IE@1224|Proteobacteria,2TVJS@28211|Alphaproteobacteria,2KCZ8@204457|Sphingomonadales 204457|Sphingomonadales P receptor - - - - - - - - - - - - Plug,TonB_dep_Rec k141_3274_2 247633.GP2143_08859 5.51e-67 213.0 COG3975@1|root,COG3975@2|Bacteria,1N69B@1224|Proteobacteria,1RY45@1236|Gammaproteobacteria,1JA09@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - Peptidase_M61 k141_12996_2 1116375.VEJY3_05070 1.24e-215 598.0 COG4974@1|root,COG4974@2|Bacteria,1PSPB@1224|Proteobacteria,1TCG3@1236|Gammaproteobacteria,1XWI6@135623|Vibrionales 135623|Vibrionales L Integrase - - - - - - - - - - - - Integrase_1,Phage_int_SAM_5 k141_12996_4 1517681.HW45_03190 2.92e-42 140.0 2AWU8@1|root,31NRE@2|Bacteria,1QKFR@1224|Proteobacteria,1TIJN@1236|Gammaproteobacteria,1XZ8Y@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_2022_1 1279017.AQYJ01000027_gene1981 1.28e-219 632.0 COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,1RPFM@1236|Gammaproteobacteria,4673P@72275|Alteromonadaceae 1236|Gammaproteobacteria M protein involved in outer membrane biogenesis asmA - - ko:K07289 - - - - ko00000 - - - AsmA k141_2022_2 1279017.AQYJ01000027_gene1982 5.4e-95 297.0 COG4206@1|root,COG4206@2|Bacteria,1MUZG@1224|Proteobacteria,1RP7I@1236|Gammaproteobacteria,463Z2@72275|Alteromonadaceae 1236|Gammaproteobacteria H COG1629 Outer membrane receptor proteins, mostly Fe transport - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - CarboxypepD_reg,Plug,TonB_dep_Rec k141_37676_1 1536774.H70357_10675 2.67e-13 71.2 COG4722@1|root,COG4722@2|Bacteria,1VYZP@1239|Firmicutes,4HXYY@91061|Bacilli,27075@186822|Paenibacillaceae 91061|Bacilli S Phage tail protein - - - - - - - - - - - - Sipho_tail k141_21033_2 1453501.JELR01000002_gene1274 1.44e-13 69.3 COG0451@1|root,COG0451@2|Bacteria,1MW32@1224|Proteobacteria,1SYQK@1236|Gammaproteobacteria 1236|Gammaproteobacteria M COG0451 Nucleoside-diphosphate-sugar epimerases - - 1.1.1.219 ko:K00091 - - - - ko00000,ko01000 - - - Epimerase k141_4468_1 28229.ND2E_4236 2.01e-81 255.0 COG4573@1|root,COG4573@2|Bacteria,1MW3Q@1224|Proteobacteria,1RQAU@1236|Gammaproteobacteria,2Q80M@267889|Colwelliaceae 1236|Gammaproteobacteria G Tagatose 6 phosphate kinase kbaZ GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034219,GO:0044425,GO:0044459,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 - ko:K16371 ko00052,ko01100,map00052,map01100 - R01069 RC00438,RC00439 ko00000,ko00001 - - iECIAI1_1343.ECIAI1_3280 Tagatose_6_P_K k141_15138_1 218284.CCDN010000001_gene1356 3.53e-115 344.0 COG1574@1|root,COG1574@2|Bacteria,1TRB6@1239|Firmicutes,4HFBR@91061|Bacilli,1ZM5P@1386|Bacillus 91061|Bacilli S Amidohydrolase family - - - - - - - - - - - - Amidohydro_3 k141_7126_2 42256.RradSPS_2010 3.46e-59 197.0 COG0761@1|root,COG0761@2|Bacteria,2GIZ7@201174|Actinobacteria,4CPHC@84995|Rubrobacteria 84995|Rubrobacteria IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis ispH - 1.17.7.4 ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05884,R08210 RC01137,RC01487 ko00000,ko00001,ko00002,ko01000 - - - LYTB k141_17477_3 1384049.CD29_07285 6.67e-26 102.0 2A6RZ@1|root,30VK4@2|Bacteria,1V5GS@1239|Firmicutes,4HHIA@91061|Bacilli,3J005@400634|Lysinibacillus 91061|Bacilli S Predicted integral membrane protein (DUF2269) - - - - - - - - - - - - DUF2269 k141_17477_4 1294265.JCM21738_5180 1.82e-28 109.0 COG0397@1|root,COG0397@2|Bacteria,1TQXD@1239|Firmicutes,4HBKH@91061|Bacilli,1ZC8A@1386|Bacillus 91061|Bacilli S Belongs to the UPF0061 (SELO) family M1-1044 - - - - - - - - - - - UPF0061 k141_28099_1 1095769.CAHF01000023_gene566 1.92e-79 251.0 COG0677@1|root,COG0677@2|Bacteria,1MUC6@1224|Proteobacteria,2VJ7A@28216|Betaproteobacteria,4763B@75682|Oxalobacteraceae 28216|Betaproteobacteria M UDP binding domain - - 1.1.1.136 ko:K13015 ko00520,map00520 - R00421 RC00291 ko00000,ko00001,ko01000,ko01005 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N k141_22504_1 1453501.JELR01000001_gene2952 5.98e-67 209.0 COG4067@1|root,COG4067@2|Bacteria,1N7Y2@1224|Proteobacteria,1S91D@1236|Gammaproteobacteria,46CZQ@72275|Alteromonadaceae 1236|Gammaproteobacteria O Putative ATP-dependant zinc protease - - - - - - - - - - - - Zn_protease k141_3275_1 1122194.AUHU01000003_gene2327 7.33e-63 218.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MV8W@1224|Proteobacteria,1RMQA@1236|Gammaproteobacteria,46619@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec k141_11875_3 218284.CCDN010000001_gene1044 7.03e-96 280.0 COG2172@1|root,COG2172@2|Bacteria,1V6V2@1239|Firmicutes,4HGYN@91061|Bacilli,1ZFKS@1386|Bacillus 91061|Bacilli F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition spoIIAB GO:0000003,GO:0000988,GO:0000989,GO:0003674,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 2.7.11.1 ko:K06379 - - - - ko00000,ko01000 - - - HATPase_c_2 k141_11875_4 218284.CCDN010000001_gene1045 5.32e-105 308.0 COG1191@1|root,COG1191@2|Bacteria,1TP3Q@1239|Firmicutes,4HC42@91061|Bacilli,1ZANZ@1386|Bacillus 91061|Bacilli K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released sigF - - ko:K03091 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r3,Sigma70_r4 k141_24806_1 218284.CCDN010000001_gene1959 3.45e-163 472.0 COG2766@1|root,COG2766@2|Bacteria,1TRTW@1239|Firmicutes,4HA8A@91061|Bacilli,1ZBM9@1386|Bacillus 91061|Bacilli T Ser protein kinase prkA - - ko:K07180 - - - - ko00000 - - - AAA_PrkA,PrkA k141_2046_1 714961.BFZC1_05378 3.17e-13 67.8 COG0614@1|root,COG0614@2|Bacteria,1TQV7@1239|Firmicutes,4HCF3@91061|Bacilli,3IWRX@400634|Lysinibacillus 91061|Bacilli P ABC transporter substrate-binding protein btuF - - ko:K02016 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - iYO844.BSU33180 Peripla_BP_2 k141_2046_2 1294265.JCM21738_1354 8.05e-88 259.0 COG1963@1|root,COG1963@2|Bacteria,1VAVC@1239|Firmicutes,4HHA6@91061|Bacilli,1ZFKA@1386|Bacillus 91061|Bacilli S protein conserved in bacteria yuiD - - ko:K09775 - - - - ko00000 - - - DUF212 k141_37704_1 1279017.AQYJ01000026_gene204 2.92e-64 202.0 COG3637@1|root,COG3637@2|Bacteria,1N7IC@1224|Proteobacteria 1224|Proteobacteria M Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - ko:K12976 - - - - ko00000,ko01000,ko01005 - - - PagL k141_3298_1 312309.VF_A0350 7.15e-52 185.0 COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,1RPSJ@1236|Gammaproteobacteria,1XTPG@135623|Vibrionales 135623|Vibrionales T containing cAMP-binding and CBS domains - - - ko:K07182 - - - - ko00000 - - - CBS,DUF294,DUF294_C,cNMP_binding k141_3298_2 675812.VHA_002559 3.45e-268 743.0 COG4146@1|root,COG4146@2|Bacteria,1MXWV@1224|Proteobacteria,1RR4S@1236|Gammaproteobacteria,1XW1R@135623|Vibrionales 135623|Vibrionales S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family yidK - - ko:K03307 - - - - ko00000 2.A.21 - - SSF k141_22549_1 396588.Tgr7_3044 5.16e-27 105.0 COG0515@1|root,COG0515@2|Bacteria,1NUIB@1224|Proteobacteria 1224|Proteobacteria KLT Protein tyrosine kinase - - - - - - - - - - - - Pkinase k141_22549_2 595460.RRSWK_04882 6.64e-21 91.3 COG0631@1|root,COG0631@2|Bacteria 2|Bacteria T protein serine/threonine phosphatase activity - - 3.1.3.16 ko:K20074 - - - - ko00000,ko01000,ko01009 - - - PP2C,PP2C_2 k141_21067_1 218284.CCDN010000001_gene34 5.4e-102 311.0 COG1461@1|root,COG1461@2|Bacteria,1TQMX@1239|Firmicutes,4HBSE@91061|Bacilli,1ZBRP@1386|Bacillus 91061|Bacilli S kinase related to dihydroxyacetone kinase yloV - - ko:K07030 - - - - ko00000 - - - Dak1_2,Dak2 k141_28127_1 1384049.CD29_18705 6.94e-07 50.1 COG2890@1|root,COG2890@2|Bacteria,1UIWK@1239|Firmicutes,4ISUT@91061|Bacilli,3IXVW@400634|Lysinibacillus 91061|Bacilli J Thiopurine S-methyltransferase (TPMT) - - - - - - - - - - - - Methyltransf_25 k141_1137_2 1453501.JELR01000002_gene1441 3.01e-105 326.0 COG0745@1|root,COG0745@2|Bacteria,1R2JU@1224|Proteobacteria 1224|Proteobacteria T cheY-homologous receiver domain - - - - - - - - - - - - Response_reg k141_1137_3 1042377.AFPJ01000028_gene2291 5.13e-42 144.0 COG0796@1|root,COG0796@2|Bacteria 2|Bacteria M Provides the (R)-glutamate required for cell wall biosynthesis - - 5.1.1.3 ko:K01776 ko00471,ko01100,map00471,map01100 - R00260 RC00302 ko00000,ko00001,ko01000,ko01011 - - - Asp_Glu_race k141_29513_1 1116375.VEJY3_20346 6.8e-108 338.0 COG0204@1|root,COG0318@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1T1II@1236|Gammaproteobacteria,1XW5B@135623|Vibrionales 135623|Vibrionales IQ AMP-binding enzyme - - - - - - - - - - - - AMP-binding,Acyltransferase,PP-binding k141_29513_2 1116375.VEJY3_20351 6.51e-145 412.0 COG1349@1|root,COG1349@2|Bacteria,1N4W8@1224|Proteobacteria,1SAKE@1236|Gammaproteobacteria,1XWS8@135623|Vibrionales 135623|Vibrionales K DeoR C terminal sensor domain - - - ko:K22103 - - - - ko00000,ko03000 - - - DeoRC,HTH_DeoR k141_29513_3 1116375.VEJY3_20356 8.75e-221 612.0 COG0673@1|root,COG0673@2|Bacteria,1MU8F@1224|Proteobacteria,1RNKY@1236|Gammaproteobacteria,1Y2F7@135623|Vibrionales 135623|Vibrionales S Oxidoreductase family, C-terminal alpha/beta domain - - 1.1.1.371 ko:K16044 ko00562,ko01120,map00562,map01120 - R09954 RC00182 ko00000,ko00001,ko01000 - - - GFO_IDH_MocA,GFO_IDH_MocA_C k141_29513_4 1116375.VEJY3_20361 2.9e-79 238.0 COG4702@1|root,COG4702@2|Bacteria,1RHRX@1224|Proteobacteria,1S7IM@1236|Gammaproteobacteria,1XX5S@135623|Vibrionales 135623|Vibrionales S Belongs to the UPF0303 family - - - - - - - - - - - - Haem_degrading k141_29513_5 1348635.BBJY01000019_gene537 7.87e-126 387.0 COG5001@1|root,COG5001@2|Bacteria,1QKYP@1224|Proteobacteria,1TJ4X@1236|Gammaproteobacteria,1Y0J5@135623|Vibrionales 135623|Vibrionales T PAS fold - - - - - - - - - - - - EAL,PAS_3 k141_29513_8 1280001.BAOA01000073_gene3388 2.74e-24 93.6 2AWDU@1|root,31N9U@2|Bacteria,1QK0Z@1224|Proteobacteria,1TI3H@1236|Gammaproteobacteria,1XYAK@135623|Vibrionales 135623|Vibrionales S Pas factor saposin fold - - - - - - - - - - - - Pas_Saposin k141_29513_9 1116375.VEJY3_20376 2.06e-25 104.0 COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,1RMNZ@1236|Gammaproteobacteria,1XUS0@135623|Vibrionales 1236|Gammaproteobacteria F Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA - - 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 - - - AMP-binding,AMP-binding_C k141_34292_1 1116375.VEJY3_17716 1.8e-170 488.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XSE1@135623|Vibrionales 135623|Vibrionales T COG2202 FOG PAS PAC domain - - - ko:K03406,ko:K03776 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - MCPsignal,PAS_3 k141_17525_1 218284.CCDN010000002_gene2902 1.24e-143 405.0 COG1182@1|root,COG1182@2|Bacteria,1UZBY@1239|Firmicutes,4HB1Z@91061|Bacilli,1ZD4D@1386|Bacillus 91061|Bacilli I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity azoR - - ko:K01118 - - - - ko00000,ko01000 - - - Flavodoxin_2 k141_17525_2 218284.CCDN010000002_gene2900 1.56e-106 310.0 2CJF8@1|root,2ZCAP@2|Bacteria,1V3BA@1239|Firmicutes,4HFSQ@91061|Bacilli,1ZG4X@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3189) - - - - - - - - - - - - DUF3189 k141_2310_2 1294265.JCM21738_3172 8.23e-43 139.0 2E6I0@1|root,33158@2|Bacteria,1VIB0@1239|Firmicutes,4HNZB@91061|Bacilli,1ZJDR@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_3497_1 745411.B3C1_01910 2.83e-71 222.0 COG1349@1|root,COG1349@2|Bacteria,1MUJG@1224|Proteobacteria,1RNW4@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Transcriptional - - - ko:K02081 - - - - ko00000,ko03000 - - - DeoRC,HTH_DeoR k141_4697_3 1347086.CCBA010000015_gene633 2.67e-34 122.0 2DKHE@1|root,309GB@2|Bacteria,1U50R@1239|Firmicutes,4IESM@91061|Bacilli,1ZI04@1386|Bacillus 91061|Bacilli S Intracellular proteinase inhibitor - - - - - - - - - - - - BsuPI k141_33236_2 1279017.AQYJ01000028_gene2545 1.13e-280 774.0 COG1282@1|root,COG1282@2|Bacteria,1MUP4@1224|Proteobacteria,1RMR4@1236|Gammaproteobacteria,464HF@72275|Alteromonadaceae 1236|Gammaproteobacteria C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane pntB GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006740,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008746,GO:0008750,GO:0009117,GO:0009987,GO:0016020,GO:0016021,GO:0016491,GO:0016651,GO:0016652,GO:0019362,GO:0019637,GO:0031224,GO:0031226,GO:0034641,GO:0036094,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050661,GO:0050662,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072524,GO:0097159,GO:1901265,GO:1901360,GO:1901363,GO:1901564 1.6.1.2 ko:K00325 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - iSBO_1134.SBO_1534,iYL1228.KPN_01527 PNTB k141_33236_3 1279017.AQYJ01000028_gene2546 1.74e-171 502.0 COG0793@1|root,COG0793@2|Bacteria,1MUA3@1224|Proteobacteria,1RR5H@1236|Gammaproteobacteria,466R3@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0793 Periplasmic protease - - - - - - - - - - - - Peptidase_S41 k141_37938_1 1294265.JCM21738_3756 4.55e-127 367.0 COG1404@1|root,COG1404@2|Bacteria,1TQ2M@1239|Firmicutes,4HBYC@91061|Bacilli,1ZPV5@1386|Bacillus 91061|Bacilli O Belongs to the peptidase S8 family aprE GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005576,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030193,GO:0030195,GO:0032101,GO:0032102,GO:0042730,GO:0043170,GO:0044238,GO:0048519,GO:0048583,GO:0048585,GO:0050789,GO:0050818,GO:0050819,GO:0050878,GO:0051239,GO:0051241,GO:0061041,GO:0061045,GO:0065007,GO:0065008,GO:0070011,GO:0071704,GO:0080134,GO:0140096,GO:1900046,GO:1900047,GO:1901564,GO:1903034,GO:1903035 3.4.21.62 ko:K01342,ko:K13277 ko02024,map02024 - - - ko00000,ko00001,ko01000,ko01002,ko03110 - - - Inhibitor_I9,Peptidase_S8,SLH k141_21322_1 218284.CCDN010000001_gene128 1.42e-157 457.0 COG0843@1|root,COG0843@2|Bacteria,1TP2U@1239|Firmicutes,4HA4X@91061|Bacilli,1ZBD5@1386|Bacillus 91061|Bacilli C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B ctaD GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009486,GO:0009987,GO:0015002,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0034220,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.9.3.1 ko:K02274 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6 - - COX1 k141_16620_1 218284.CCDN010000002_gene2730 5.09e-136 404.0 COG2213@1|root,COG4668@1|root,COG2213@2|Bacteria,COG4668@2|Bacteria,1TPE3@1239|Firmicutes,4HAVV@91061|Bacilli,1ZC81@1386|Bacillus 91061|Bacilli G COG2213 Phosphotransferase system, mannitol-specific IIBC component mtlA - 2.7.1.197 ko:K02798,ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 M00274 R02704 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1.12,4.A.2.1.2,4.A.2.1.24,4.A.2.1.5 - - PTS_EIIA_2,PTS_EIIC,PTS_IIB k141_8142_1 1042377.AFPJ01000042_gene1022 5.18e-80 249.0 COG1649@1|root,COG1649@2|Bacteria 2|Bacteria F PFAM Uncharacterised BCR, COG1649 - - - - - - - - - - - - GHL10,SLH,WG_beta_rep k141_8142_2 1042377.AFPJ01000042_gene1021 1.9e-118 351.0 COG0524@1|root,COG0524@2|Bacteria,1MX38@1224|Proteobacteria,1RRWT@1236|Gammaproteobacteria,466SF@72275|Alteromonadaceae 1236|Gammaproteobacteria G COG0524 Sugar kinases, ribokinase family scrK - 2.7.1.4 ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 - R00760,R00867,R03920 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB k141_8142_3 1042377.AFPJ01000042_gene1020 1.12e-27 110.0 COG2942@1|root,COG2942@2|Bacteria,1MX1J@1224|Proteobacteria,1RSCF@1236|Gammaproteobacteria,465YE@72275|Alteromonadaceae 1236|Gammaproteobacteria G N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) yihS GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006066,GO:0006082,GO:0006790,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016853,GO:0016860,GO:0016861,GO:0019637,GO:0034308,GO:0042180,GO:0042802,GO:0044237,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0050089,GO:0061593,GO:0061720,GO:0071704,GO:1901135,GO:1901136,GO:1901575,GO:1901615,GO:1902776,GO:1902777 5.3.1.31 ko:K18479 - - R10765 RC00376 ko00000,ko01000 - - - GlcNAc_2-epim k141_28365_1 1453501.JELR01000002_gene543 2.39e-144 408.0 COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,1RMSY@1236|Gammaproteobacteria,466QA@72275|Alteromonadaceae 1236|Gammaproteobacteria H riboflavin synthase, alpha ribE - 2.5.1.9 ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00066 RC00958,RC00960 ko00000,ko00001,ko00002,ko01000 - - - Lum_binding k141_3498_2 714943.Mucpa_1493 3.54e-45 154.0 COG0384@1|root,COG0384@2|Bacteria,4NEWM@976|Bacteroidetes,1IP44@117747|Sphingobacteriia 976|Bacteroidetes S Phenazine biosynthesis-like protein - - - - - - - - - - - - PhzC-PhzF k141_21323_1 1123279.ATUS01000001_gene1622 6.61e-27 107.0 COG0208@1|root,COG0208@2|Bacteria,1MWUS@1224|Proteobacteria,1RMJC@1236|Gammaproteobacteria,1J4R2@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdB - 1.17.4.1 ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - iJN746.PP_1177 Ribonuc_red_sm k141_16621_1 517418.Ctha_1801 6.88e-27 106.0 COG2126@1|root,COG2126@2|Bacteria,1FDC0@1090|Chlorobi 1090|Chlorobi J Ion transport 2 domain protein - - - ko:K10716 - - - - ko00000,ko02000 1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6 - - Ion_trans k141_17810_1 223926.28809406 9.85e-66 213.0 COG1030@1|root,COG1030@2|Bacteria,1MUJN@1224|Proteobacteria,1RN3U@1236|Gammaproteobacteria,1XV48@135623|Vibrionales 135623|Vibrionales O COG1030 Membrane-bound serine protease (ClpP class) - - - ko:K07403 - - - - ko00000 - - - NfeD k141_17810_2 1116375.VEJY3_18626 0.0 1255.0 COG3322@1|root,COG5001@1|root,COG3322@2|Bacteria,COG5001@2|Bacteria,1NSEP@1224|Proteobacteria,1SMC0@1236|Gammaproteobacteria,1XVRS@135623|Vibrionales 135623|Vibrionales T CHASE4 domain - - - - - - - - - - - - CHASE4,EAL,GGDEF,PAS_9 k141_17810_3 1280001.BAOA01000074_gene3434 4.42e-08 51.2 2B6RZ@1|root,31ZQY@2|Bacteria,1QKJ2@1224|Proteobacteria,1TIPD@1236|Gammaproteobacteria,1XZEX@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_17810_4 1116375.VEJY3_18641 4.99e-212 589.0 COG3250@1|root,COG3250@2|Bacteria,1R87I@1224|Proteobacteria,1RZ7F@1236|Gammaproteobacteria,1XV1Y@135623|Vibrionales 135623|Vibrionales G Protein of unknown function (DUF2804) - - - - - - - - - - - - DUF2804 k141_17810_5 1116375.VEJY3_18811 1.44e-106 308.0 COG3265@1|root,COG3265@2|Bacteria,1RHD0@1224|Proteobacteria,1RP41@1236|Gammaproteobacteria,1XXCW@135623|Vibrionales 135623|Vibrionales G Shikimate kinase - - 2.7.1.12 ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 - R01737 RC00002,RC00017 ko00000,ko00001,ko01000 - - - SKI k141_17810_6 1116375.VEJY3_18816 1.33e-311 853.0 COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,1RMR6@1236|Gammaproteobacteria,1XUB5@135623|Vibrionales 135623|Vibrionales Q COG4664 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - - - - - - - - - - DctM k141_17810_7 1116375.VEJY3_18821 2.78e-119 342.0 COG4665@1|root,COG4665@2|Bacteria,1RDPJ@1224|Proteobacteria,1S4KV@1236|Gammaproteobacteria,1XV04@135623|Vibrionales 135623|Vibrionales Q COG4665 TRAP-type mannitol chloroaromatic compound transport system, small permease component - - - - - - - - - - - - DctQ k141_17810_8 1116375.VEJY3_18826 5.92e-235 647.0 COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,1RNCK@1236|Gammaproteobacteria,1XVRQ@135623|Vibrionales 135623|Vibrionales Q COG4663 TRAP-type mannitol chloroaromatic compound transport system, periplasmic component - - - - - - - - - - - - DctP k141_17810_9 298386.PBPRB1364 4.5e-09 55.5 2AXZ3@1|root,31Q0K@2|Bacteria,1QMP6@1224|Proteobacteria,1TJYT@1236|Gammaproteobacteria,1Y1V6@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_17810_10 223926.28809397 3.98e-89 265.0 2C852@1|root,32YB2@2|Bacteria,1RH28@1224|Proteobacteria,1SX3D@1236|Gammaproteobacteria,1XYEF@135623|Vibrionales 135623|Vibrionales S Domain of unknown function (DUF4136) VPA1096 - - - - - - - - - - - DUF4136 k141_17810_11 1116375.VEJY3_18931 1.73e-118 343.0 COG1376@1|root,COG1376@2|Bacteria,1RA7Q@1224|Proteobacteria,1S5JW@1236|Gammaproteobacteria,1XVZN@135623|Vibrionales 135623|Vibrionales S L,D-transpeptidase catalytic domain - - - - - - - - - - - - YkuD_2 k141_17810_12 1116375.VEJY3_18936 6.11e-67 205.0 COG0494@1|root,COG0494@2|Bacteria,1NE63@1224|Proteobacteria,1SDNG@1236|Gammaproteobacteria,1XY1N@135623|Vibrionales 135623|Vibrionales L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - - - - - - - - - - NUDIX k141_17810_13 223926.28809391 1.22e-21 85.5 2BHGG@1|root,32BIM@2|Bacteria,1QKMF@1224|Proteobacteria,1TIRX@1236|Gammaproteobacteria,1XZJ0@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_37939_1 218284.CCDN010000001_gene1473 2.58e-154 441.0 COG2046@1|root,COG2046@2|Bacteria,1TR4C@1239|Firmicutes,4HC20@91061|Bacilli,1ZCB4@1386|Bacillus 91061|Bacilli P Belongs to the sulfate adenylyltransferase family sat - 2.7.7.4 ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176,M00596 R00529,R04929 RC02809,RC02889 ko00000,ko00001,ko00002,ko01000 - - - ATP-sulfurylase,PUA_2 k141_2312_1 42565.FP66_03220 1.62e-110 329.0 COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,1T248@1236|Gammaproteobacteria,1XH8I@135619|Oceanospirillales 135619|Oceanospirillales T Histidine kinase - - 2.7.13.3 ko:K20975 ko02020,ko02025,map02020,map02025 M00820 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,Response_reg k141_3499_1 218284.CCDN010000002_gene2534 4.82e-103 306.0 COG0604@1|root,COG0604@2|Bacteria,1TT5J@1239|Firmicutes,4HCXG@91061|Bacilli,1ZBNX@1386|Bacillus 91061|Bacilli C alcohol dehydrogenase - - - - - - - - - - - - - k141_33238_1 338963.Pcar_0024 4.72e-64 205.0 COG0451@1|root,COG0451@2|Bacteria,1MVE4@1224|Proteobacteria,42MC1@68525|delta/epsilon subdivisions,2WJ24@28221|Deltaproteobacteria,43UKS@69541|Desulfuromonadales 28221|Deltaproteobacteria F Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose hldD - 5.1.3.20 ko:K03274 ko00540,ko01100,map00540,map01100 M00064 R05176 RC01291 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Epimerase k141_4699_1 460265.Mnod_7168 1.81e-48 156.0 COG2824@1|root,COG2824@2|Bacteria,1RGUU@1224|Proteobacteria,2UFDJ@28211|Alphaproteobacteria,1JVC1@119045|Methylobacteriaceae 28211|Alphaproteobacteria P PFAM PhnA protein phnA - - ko:K06193 ko01120,map01120 - - - ko00000 - - - PhnA,PhnA_Zn_Ribbon k141_4699_2 318586.Pden_4691 1.73e-21 91.7 COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,2TUF7@28211|Alphaproteobacteria,2PW58@265|Paracoccus 28211|Alphaproteobacteria I CDP-alcohol phosphatidyltransferase pssA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.8.8 ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 M00093 R01800 RC00002,RC00017,RC02795 ko00000,ko00001,ko00002,ko01000 - - - CDP-OH_P_tran_2,CDP-OH_P_transf k141_21324_1 218284.CCDN010000002_gene2856 4.69e-164 470.0 COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,4HAD5@91061|Bacilli,1ZC3C@1386|Bacillus 91061|Bacilli E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases gltD - 1.4.1.13,1.4.1.14 ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - iSB619.SA_RS02450 Fer4_20,Pyr_redox_2 k141_2313_1 1499685.CCFJ01000054_gene1636 1.44e-88 268.0 COG1875@1|root,COG1875@2|Bacteria,1UHTD@1239|Firmicutes,4HA4V@91061|Bacilli,1ZDIF@1386|Bacillus 91061|Bacilli T ATPase related to phosphate starvation-inducible protein PhoH ylaK - - ko:K07175 - - - - ko00000 - - - PIN_4,PhoH k141_33239_1 1121939.L861_23425 1.15e-65 206.0 COG2188@1|root,COG2188@2|Bacteria,1MUEB@1224|Proteobacteria 1224|Proteobacteria K Transcriptional regulator - - - ko:K03710 - - - - ko00000,ko03000 - - - GntR,UTRA k141_37953_8 674977.VMC_39030 0.0 918.0 COG0017@1|root,COG0017@2|Bacteria,1MWFV@1224|Proteobacteria,1RMU4@1236|Gammaproteobacteria,1XSJD@135623|Vibrionales 135623|Vibrionales J COG0017 Aspartyl asparaginyl-tRNA synthetases asnS GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.22 ko:K01893 ko00970,map00970 M00359,M00360 R03648 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2,tRNA_anti-codon k141_37953_9 1116375.VEJY3_10000 8.8e-34 117.0 2ENSJ@1|root,33GDR@2|Bacteria,1NHCI@1224|Proteobacteria,1SCIY@1236|Gammaproteobacteria,1XYX5@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_37953_10 1116375.VEJY3_10005 1.37e-272 753.0 COG1167@1|root,COG1167@2|Bacteria,1MV6F@1224|Proteobacteria,1RMQ0@1236|Gammaproteobacteria,1XTIR@135623|Vibrionales 135623|Vibrionales K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs - - - - - - - - - - - - Aminotran_1_2,GntR k141_37953_11 1116375.VEJY3_10010 2.94e-50 160.0 2EUUC@1|root,31NB1@2|Bacteria,1QK22@1224|Proteobacteria,1TI4N@1236|Gammaproteobacteria,1XYD7@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_37953_12 1116375.VEJY3_10015 9.37e-275 753.0 COG1448@1|root,COG1448@2|Bacteria,1MUT0@1224|Proteobacteria,1RN02@1236|Gammaproteobacteria,1XTX4@135623|Vibrionales 135623|Vibrionales E COG1448 Aspartate tyrosine aromatic aminotransferase aspC - 2.6.1.57 ko:K00832 ko00270,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 M00024,M00025,M00034,M00040 R00694,R00734,R01731,R07396,R10845 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k141_37953_13 1116375.VEJY3_10020 1.49e-120 347.0 2BFU8@1|root,329PC@2|Bacteria,1QJDH@1224|Proteobacteria,1THCM@1236|Gammaproteobacteria,1XTXQ@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - OMP_b-brl k141_37953_14 223926.28806894 0.0 1170.0 COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,1RPSJ@1236|Gammaproteobacteria,1XSDF@135623|Vibrionales 135623|Vibrionales T containing cAMP-binding and CBS domains - - - ko:K07182 - - - - ko00000 - - - CBS,DUF294,DUF294_C,cNMP_binding k141_37953_15 223926.28806895 2.23e-138 395.0 COG0847@1|root,COG0847@2|Bacteria,1RAF1@1224|Proteobacteria,1S20V@1236|Gammaproteobacteria,1XSA6@135623|Vibrionales 135623|Vibrionales L COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases - - 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - RNase_T k141_37953_16 1116375.VEJY3_10035 0.0 889.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XU8V@135623|Vibrionales 135623|Vibrionales NT methyl-accepting chemotaxis protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal,dCache_1 k141_37953_17 1116375.VEJY3_10040 0.0 989.0 COG1292@1|root,COG1292@2|Bacteria,1MV0K@1224|Proteobacteria,1RP3E@1236|Gammaproteobacteria,1XU3K@135623|Vibrionales 135623|Vibrionales U Belongs to the BCCT transporter (TC 2.A.15) family butA - - ko:K03451 - - - - ko00000 2.A.15 - - BCCT k141_37953_18 1219076.N646_0987 1.49e-96 283.0 COG1846@1|root,COG1846@2|Bacteria,1RF8X@1224|Proteobacteria,1S4RW@1236|Gammaproteobacteria,1XX10@135623|Vibrionales 135623|Vibrionales K COG1846 Transcriptional regulators - - - - - - - - - - - - MarR k141_37953_19 1116375.VEJY3_10050 1.48e-133 380.0 COG2197@1|root,COG2197@2|Bacteria,1R9GN@1224|Proteobacteria,1S4YI@1236|Gammaproteobacteria,1XUAU@135623|Vibrionales 135623|Vibrionales K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - ko:K07684 ko02020,map02020 M00471 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg k141_37953_20 1116375.VEJY3_10055 2.57e-293 804.0 COG4564@1|root,COG4564@2|Bacteria,1QTY1@1224|Proteobacteria,1T1XV@1236|Gammaproteobacteria,1XUBC@135623|Vibrionales 135623|Vibrionales T Signal transduction histidine kinase - - 2.7.13.3 ko:K02480 - - - - ko00000,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA_3,sCache_2 k141_37953_21 1116375.VEJY3_10060 5.72e-283 776.0 COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,1RMR6@1236|Gammaproteobacteria,1XUVI@135623|Vibrionales 135623|Vibrionales Q COG4664 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - - - - - - - - - - DctM k141_37953_22 1116375.VEJY3_10065 9.39e-121 345.0 COG4665@1|root,COG4665@2|Bacteria,1REH8@1224|Proteobacteria,1S44W@1236|Gammaproteobacteria,1XTZR@135623|Vibrionales 135623|Vibrionales Q TRAP-type mannitol chloroaromatic compound transport system, small permease component - - - - - - - - - - - - DctQ k141_37953_23 1219076.N646_0992 5.59e-250 687.0 COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,1RNCK@1236|Gammaproteobacteria,1XV1B@135623|Vibrionales 135623|Vibrionales Q Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - - - - - - - - - - DctP k141_37953_24 223926.28806904 6.3e-55 175.0 COG0735@1|root,COG0735@2|Bacteria,1QJWN@1224|Proteobacteria,1THYF@1236|Gammaproteobacteria,1XXWI@135623|Vibrionales 135623|Vibrionales P belongs to the Fur family VV2111 - - - - - - - - - - - - k141_37953_25 223926.28806905 8.53e-140 397.0 2CEWJ@1|root,32S0P@2|Bacteria,1N30H@1224|Proteobacteria,1S9KS@1236|Gammaproteobacteria,1XTGY@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF2982) VV12961 - - - - - - - - - - - DUF2982 k141_37953_26 223926.28806906 2.42e-158 443.0 COG0491@1|root,COG0491@2|Bacteria,1MUDN@1224|Proteobacteria,1RMMG@1236|Gammaproteobacteria,1XU1B@135623|Vibrionales 135623|Vibrionales S COG0491 Zn-dependent hydrolases, including glyoxylases ycbL - - - - - - - - - - - Lactamase_B k141_21368_1 1294265.JCM21738_1013 9.07e-68 224.0 COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,4HAI0@91061|Bacilli,1ZAVE@1386|Bacillus 91061|Bacilli P P-type ATPase copA - 3.6.3.54 ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - - E1-E2_ATPase,HMA,Hydrolase k141_31787_1 1121468.AUBR01000018_gene2694 7.89e-67 214.0 COG0473@1|root,COG0473@2|Bacteria,1TPEM@1239|Firmicutes,24A63@186801|Clostridia,42EVK@68295|Thermoanaerobacterales 186801|Clostridia C PFAM isocitrate isopropylmalate dehydrogenase icd - 1.1.1.41 ko:K00030 ko00020,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010 R00709 RC00114 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh k141_4752_1 223926.28805107 7.67e-109 320.0 COG1295@1|root,COG1295@2|Bacteria,1QICW@1224|Proteobacteria,1RMKI@1236|Gammaproteobacteria,1XUTA@135623|Vibrionales 135623|Vibrionales S membrane rbn - - ko:K07058 - - - - ko00000 - - - Virul_fac_BrkB k141_4752_2 223926.28805106 5.1e-128 366.0 28NM7@1|root,2ZBMT@2|Bacteria,1R9Y9@1224|Proteobacteria,1S227@1236|Gammaproteobacteria,1XSXZ@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF2959) - - - - - - - - - - - - DUF2959 k141_4752_3 223926.28805104 0.0 1172.0 COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,1RMJB@1236|Gammaproteobacteria,1XTQJ@135623|Vibrionales 135623|Vibrionales T membrane GTPase involved in stress response typA - - ko:K06207 - - - - ko00000 - - - EFG_C,GTP_EFTU,GTP_EFTU_D2 k141_4752_4 1248232.BANQ01000013_gene984 0.0 908.0 COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,1RMD1@1236|Gammaproteobacteria,1XTYT@135623|Vibrionales 135623|Vibrionales E glutamine synthetase glnA GO:0003674,GO:0003824,GO:0004356,GO:0006082,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C,Gln-synt_N k141_4752_5 223926.28805102 3.97e-92 274.0 2E42P@1|root,32YZ5@2|Bacteria,1N868@1224|Proteobacteria,1TAFS@1236|Gammaproteobacteria,1XUT4@135623|Vibrionales 135623|Vibrionales S Domain of unknown function (DUF4124) VP0120 - - - - - - - - - - - DUF4124 k141_4752_6 1116375.VEJY3_00540 3.85e-236 651.0 COG3852@1|root,COG3852@2|Bacteria,1MVN6@1224|Proteobacteria,1RN15@1236|Gammaproteobacteria,1XTJP@135623|Vibrionales 135623|Vibrionales T nitrogen regulation protein glnL - 2.7.13.3 ko:K07708 ko02020,map02020 M00497 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS k141_4752_7 1116375.VEJY3_00535 0.0 910.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1XUQI@135623|Vibrionales 135623|Vibrionales T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains glnG - - ko:K07712 ko02020,map02020 M00497 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat k141_4752_8 1116375.VEJY3_00530 0.0 1351.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RRW1@1236|Gammaproteobacteria,1XVII@135623|Vibrionales 135623|Vibrionales T signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - - - - - - - - - - EAL,GGDEF,HAMP,dCache_1 k141_4752_9 223926.28805098 4.07e-80 245.0 COG1816@1|root,COG1816@2|Bacteria,1MWBV@1224|Proteobacteria,1RNVI@1236|Gammaproteobacteria,1XU9B@135623|Vibrionales 135623|Vibrionales F COG1816 Adenosine deaminase add GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009119,GO:0009163,GO:0009164,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659 3.5.4.4 ko:K01488 ko00230,ko01100,ko05340,map00230,map01100,map05340 - R01560,R02556 RC00477 ko00000,ko00001,ko01000 - - - A_deaminase k141_15338_1 1461580.CCAS010000024_gene2462 4.49e-68 227.0 COG1595@1|root,COG1595@2|Bacteria,1U9I0@1239|Firmicutes,4IJNF@91061|Bacilli,1ZC9D@1386|Bacillus 91061|Bacilli K Domain of unknown function (DUF4179) - - - - - - - - - - - - DUF4179,Sigma70_r4,Sigma70_r4_2,zf-HC2 k141_28419_1 1279017.AQYJ01000028_gene2319 4.22e-205 578.0 COG1252@1|root,COG1252@2|Bacteria,1MX96@1224|Proteobacteria,1RM9I@1236|Gammaproteobacteria,464B3@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1252 NADH dehydrogenase, FAD-containing subunit ndh - 1.6.99.3 ko:K03885 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - Pyr_redox_2 k141_37954_1 1280001.BAOA01000021_gene790 1.01e-85 260.0 2AX1N@1|root,31NZV@2|Bacteria,1RI5Q@1224|Proteobacteria,1S6GI@1236|Gammaproteobacteria,1XTQU@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF2806) VV10722 - - - - - - - - - - - DUF2806 k141_21369_1 1267535.KB906767_gene1049 1.62e-114 343.0 COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,3Y3IF@57723|Acidobacteria,2JIPC@204432|Acidobacteriia 204432|Acidobacteriia HP PFAM UBA THIF-type NAD FAD binding - - 2.7.7.80,2.8.1.11 ko:K21147 ko04122,map04122 - R07459,R07461 RC00043 ko00000,ko00001,ko01000 - - - Rhodanese,ThiF,ThiS k141_36673_1 1294265.JCM21738_2980 1.3e-123 361.0 COG1017@1|root,COG1018@1|root,COG1017@2|Bacteria,COG1018@2|Bacteria,1TRG2@1239|Firmicutes,4HAU3@91061|Bacilli,1ZAP9@1386|Bacillus 91061|Bacilli C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress hmp GO:0000041,GO:0000166,GO:0001505,GO:0003674,GO:0003824,GO:0004155,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006826,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008941,GO:0009056,GO:0009987,GO:0015669,GO:0015671,GO:0015893,GO:0016491,GO:0016645,GO:0016646,GO:0016705,GO:0016708,GO:0017144,GO:0019825,GO:0030001,GO:0033554,GO:0034641,GO:0036094,GO:0042133,GO:0042135,GO:0042221,GO:0042493,GO:0042737,GO:0043167,GO:0043168,GO:0044237,GO:0044248,GO:0044270,GO:0044464,GO:0046209,GO:0046210,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051213,GO:0051234,GO:0051409,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0071500,GO:0071949,GO:0072593,GO:0097159,GO:1901265,GO:1901363,GO:2001057 1.14.12.17,1.18.1.3 ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 M00538 R02550,R03562,R05666,R09513 RC00269,RC00490,RC02556 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_6,Globin,NAD_binding_1 k141_30649_1 218284.CCDN010000012_gene4448 2.17e-46 150.0 2DRM3@1|root,33C8V@2|Bacteria,1VKUE@1239|Firmicutes,4HRJC@91061|Bacilli,1ZRYA@1386|Bacillus 91061|Bacilli S SigmaK-factor processing regulatory protein BofA bofA - - ko:K06317 - - - - ko00000 - - - BofA k141_3557_1 279010.BL00983 9.28e-145 424.0 2DB9U@1|root,2Z7Z6@2|Bacteria,1TR67@1239|Firmicutes,4HCTZ@91061|Bacilli,1ZEZR@1386|Bacillus 91061|Bacilli S Phage portal protein, SPP1 Gp6-like - - - - - - - - - - - - Phage_prot_Gp6 k141_3557_2 1196031.ALEG01000039_gene1286 2.09e-241 669.0 COG1783@1|root,COG1783@2|Bacteria,1TT2C@1239|Firmicutes,4H9S2@91061|Bacilli,1ZCZD@1386|Bacillus 91061|Bacilli S Terminase-like family - - - - - - - - - - - - Terminase_3,Terminase_6,Terminase_6C k141_3557_3 764299.STRIC_2523 1.57e-28 109.0 COG3728@1|root,COG3728@2|Bacteria,1W469@1239|Firmicutes,4I1BP@91061|Bacilli 91061|Bacilli L DNA packaging - - - - - - - - - - - - - k141_21370_1 545693.BMQ_0565 6.77e-15 75.1 COG0189@1|root,COG0189@2|Bacteria,1U4ME@1239|Firmicutes,4HFD2@91061|Bacilli,1ZBNP@1386|Bacillus 91061|Bacilli HJ YheC/D like ATP-grasp yheC - - - - - - - - - - - ATPgrasp_YheCD k141_21370_2 35841.BT1A1_1173 4.3e-07 53.9 COG0189@1|root,COG0189@2|Bacteria,1TSWS@1239|Firmicutes,4HCJA@91061|Bacilli,1ZAR6@1386|Bacillus 91061|Bacilli HJ YheC/D like ATP-grasp yheD GO:0005575,GO:0005623,GO:0042601,GO:0042763,GO:0044464 - - - - - - - - - - ATPgrasp_YheCD k141_37955_1 218284.CCDN010000001_gene1804 7.09e-166 484.0 COG2366@1|root,COG2366@2|Bacteria,1UFHA@1239|Firmicutes,4HACM@91061|Bacilli,1ZCMT@1386|Bacillus 91061|Bacilli S Penicillin amidase acyII - 3.5.1.11 ko:K01434 ko00311,ko01130,map00311,map01130 - R02170 RC00166,RC00328 ko00000,ko00001,ko01000,ko01002 - - - Penicil_amidase k141_4754_1 42565.FP66_14275 2.08e-174 495.0 COG1157@1|root,COG1157@2|Bacteria,1MUH6@1224|Proteobacteria,1RM9W@1236|Gammaproteobacteria,1XHGZ@135619|Oceanospirillales 135619|Oceanospirillales NU Involved in type III protein export during flagellum assembly fliI - 3.6.3.14 ko:K02412 ko02040,map02040 - - - ko00000,ko00001,ko01000,ko02035,ko02044 3.A.6.2,3.A.6.3 - - ATP-synt_ab,ATP-synt_ab_N k141_8189_1 666686.B1NLA3E_04190 3.69e-76 235.0 COG0411@1|root,COG0411@2|Bacteria,1TR0P@1239|Firmicutes,4HASG@91061|Bacilli,1ZB0Q@1386|Bacillus 91061|Bacilli E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component - - - ko:K01995 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C k141_28421_1 1121090.KB894685_gene3405 5.26e-15 76.3 COG0823@1|root,COG0823@2|Bacteria,1V6S1@1239|Firmicutes,4HJJ3@91061|Bacilli,1ZETB@1386|Bacillus 91061|Bacilli U Involved in the tonB-independent uptake of proteins - - - - - - - - - - - - PD40 k141_28421_2 1294265.JCM21738_1543 1.29e-49 158.0 29S7W@1|root,30DCD@2|Bacteria,1UB4V@1239|Firmicutes,4IMHF@91061|Bacilli,1ZK5X@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_15339_1 42565.FP66_00665 5.69e-137 398.0 COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,1RMKV@1236|Gammaproteobacteria,1XH83@135619|Oceanospirillales 135619|Oceanospirillales E Amino acid permease - - - - - - - - - - - - AA_permease_2 k141_37956_1 635013.TherJR_0497 2.52e-37 144.0 COG0607@1|root,COG2897@1|root,COG0607@2|Bacteria,COG2897@2|Bacteria,1UIF9@1239|Firmicutes,24JX7@186801|Clostridia,2628W@186807|Peptococcaceae 186801|Clostridia M PFAM Rhodanese-like domain - - - - - - - - - - - - Rhodanese k141_4755_1 1345697.M493_08340 7.95e-61 203.0 COG4191@1|root,COG4191@2|Bacteria,1UY9H@1239|Firmicutes,4HC9C@91061|Bacilli,1WECP@129337|Geobacillus 91061|Bacilli T 5TMR of 5TMR-LYT kinB - 2.7.13.3 ko:K07697 ko02020,map02020 M00485 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - 5TM-5TMR_LYT,HATPase_c,HisKA k141_21372_1 118173.KB235914_gene4160 4.98e-41 154.0 COG0025@1|root,COG0569@1|root,COG0025@2|Bacteria,COG0569@2|Bacteria,1G21K@1117|Cyanobacteria,1H9AE@1150|Oscillatoriales 1117|Cyanobacteria P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family nhaP - - - - - - - - - - - Na_H_Exchanger,TrkA_N k141_3559_1 1294265.JCM21738_2015 1.98e-145 414.0 COG2252@1|root,COG2252@2|Bacteria,1TQC6@1239|Firmicutes,4HANG@91061|Bacilli,1ZARH@1386|Bacillus 91061|Bacilli S permease pbuG - - ko:K06901 - - - - ko00000,ko02000 2.A.1.40 - - Xan_ur_permease k141_37957_2 218284.CCDN010000001_gene105 8.96e-85 258.0 COG3480@1|root,COG3480@2|Bacteria,1TRUF@1239|Firmicutes,4HBAY@91061|Bacilli,1ZAW6@1386|Bacillus 91061|Bacilli T Belongs to the peptidase S16 family ylbL - - ko:K07177 ko02024,map02024 - - - ko00000,ko00001,ko01002 - - - Lon_C,PDZ_2 k141_25101_1 218284.CCDN010000001_gene1238 7.36e-92 283.0 COG0477@1|root,COG2814@2|Bacteria,1VSW8@1239|Firmicutes,4HUQC@91061|Bacilli,1ZAS8@1386|Bacillus 91061|Bacilli EGP the major facilitator superfamily - - - - - - - - - - - - MFS_1 k141_25101_2 218284.CCDN010000001_gene1237 1.38e-73 222.0 COG1846@1|root,COG1846@2|Bacteria,1V3P7@1239|Firmicutes,4HPNY@91061|Bacilli,1ZHZC@1386|Bacillus 91061|Bacilli K transcriptional ypoP GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - - - - - - - - - - MarR k141_3769_2 1042377.AFPJ01000004_gene414 2.59e-159 455.0 COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1MWCC@1224|Proteobacteria,1RNGC@1236|Gammaproteobacteria,465FU@72275|Alteromonadaceae 1236|Gammaproteobacteria K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon birA GO:0000166,GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004077,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009305,GO:0009374,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0017053,GO:0017076,GO:0017144,GO:0018130,GO:0018271,GO:0019538,GO:0019752,GO:0019842,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032991,GO:0033218,GO:0033293,GO:0034641,GO:0035639,GO:0036094,GO:0036211,GO:0042364,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043565,GO:0043603,GO:0043604,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681,GO:1990837 6.3.4.15 ko:K03524 ko00780,ko01100,map00780,map01100 - R01074,R05145 RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko01000,ko03000 - - - BPL_C,BPL_LplA_LipB,HTH_11 k141_3769_3 1279017.AQYJ01000011_gene3048 8.5e-163 468.0 COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,1RM8U@1236|Gammaproteobacteria,464PJ@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids alr - 5.1.1.1 ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 - R00401 RC00285 ko00000,ko00001,ko01000,ko01011 - - - Ala_racemase_C,Ala_racemase_N k141_3769_4 1042377.AFPJ01000004_gene412 2.34e-141 415.0 COG1668@1|root,COG1668@2|Bacteria,1R3RG@1224|Proteobacteria,1RQT1@1236|Gammaproteobacteria,46CSP@72275|Alteromonadaceae 1236|Gammaproteobacteria CP ABC-2 family transporter protein natB - - ko:K09696 ko02010,ko02020,map02010,map02020 M00253 - - ko00000,ko00001,ko00002,ko02000 3.A.1.115 - - ABC2_membrane_2,ABC2_membrane_3 k141_3769_5 1453501.JELR01000005_gene1701 3.57e-90 271.0 COG4555@1|root,COG4555@2|Bacteria,1QU2T@1224|Proteobacteria,1RY2V@1236|Gammaproteobacteria,46CK1@72275|Alteromonadaceae 1236|Gammaproteobacteria CP ATPases associated with a variety of cellular activities natA - 3.6.3.7 ko:K09697 ko02010,ko02020,map02010,map02020 M00253 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.115 - - ABC_tran k141_13275_1 1279017.AQYJ01000029_gene3841 5.55e-201 567.0 COG0007@1|root,COG1648@1|root,COG0007@2|Bacteria,COG1648@2|Bacteria,1MUI0@1224|Proteobacteria,1RM9V@1236|Gammaproteobacteria,4645Q@72275|Alteromonadaceae 1236|Gammaproteobacteria H Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme cysG - 1.3.1.76,2.1.1.107,4.99.1.4 ko:K02302,ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02864,R03194,R03947 RC00003,RC00871,RC01012,RC01034 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_3999 CysG_dimeriser,NAD_binding_7,Sirohm_synth_M,TP_methylase k141_6192_1 1131730.BAVI_00550 2.65e-145 419.0 COG1175@1|root,COG1175@2|Bacteria,1TR2A@1239|Firmicutes,4HB8H@91061|Bacilli,1ZBHD@1386|Bacillus 91061|Bacilli P COG1175 ABC-type sugar transport systems, permease components malC GO:0003674,GO:0003824,GO:0005215,GO:0005363,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015154,GO:0015157,GO:0015399,GO:0015405,GO:0015422,GO:0015423,GO:0015766,GO:0015768,GO:0015772,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0032991,GO:0034219,GO:0042623,GO:0042626,GO:0043190,GO:0043211,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990060,GO:1990351 - ko:K15771 ko02010,map02010 M00491 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.16,3.A.1.1.2 - iYO844.BSU34150 BPD_transp_1 k141_1320_1 1294265.JCM21738_83 2.1e-109 317.0 COG4862@1|root,COG4862@2|Bacteria,1V1B7@1239|Firmicutes,4HBM5@91061|Bacilli,1ZF7G@1386|Bacillus 91061|Bacilli NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC mecB GO:0007154,GO:0008150,GO:0009292,GO:0009294,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0044764,GO:0050896,GO:0051704,GO:0051716,GO:0071496 - ko:K16511 - - - - ko00000 - - - MecA k141_27483_1 862751.SACTE_0437 8.78e-29 120.0 COG0745@1|root,COG1511@1|root,COG2203@1|root,COG4251@1|root,COG0745@2|Bacteria,COG1511@2|Bacteria,COG2203@2|Bacteria,COG4251@2|Bacteria,2GKQX@201174|Actinobacteria 201174|Actinobacteria T Histidine kinase - - - - - - - - - - - - GAF_2,HAMP,HATPase_c,HisKA,Response_reg k141_35797_1 1196031.ALEG01000039_gene1295 1.78e-22 90.9 2DNPK@1|root,32YFU@2|Bacteria,1VFCK@1239|Firmicutes,4HQNX@91061|Bacilli,1ZK6M@1386|Bacillus 91061|Bacilli S Bacteriophage HK97-gp10, putative tail-component - - - - - - - - - - - - HK97-gp10_like k141_35797_2 279010.BL00972 3.76e-44 148.0 2EE4X@1|root,337ZI@2|Bacteria,1VJ70@1239|Firmicutes,4HPMA@91061|Bacilli,1ZKBX@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3168) - - - - - - - - - - - - DUF3168 k141_28754_1 1121422.AUMW01000003_gene812 3.78e-113 340.0 COG0154@1|root,COG0154@2|Bacteria,1TP0C@1239|Firmicutes,24911@186801|Clostridia,2613E@186807|Peptococcaceae 186801|Clostridia J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) gatA - 3.5.1.4,6.3.5.6,6.3.5.7 ko:K01426,ko:K02433 ko00330,ko00360,ko00380,ko00627,ko00643,ko00970,ko01100,ko01120,map00330,map00360,map00380,map00627,map00643,map00970,map01100,map01120 - R02540,R03096,R03180,R03905,R03909,R04212,R05551,R05590 RC00010,RC00100,RC00950,RC01025 ko00000,ko00001,ko01000,ko03029 - - - Amidase k141_4913_1 1453501.JELR01000002_gene1097 2.82e-103 300.0 COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,1S247@1236|Gammaproteobacteria,466J1@72275|Alteromonadaceae 1236|Gammaproteobacteria J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions def - 3.5.1.88 ko:K01462 - - - - ko00000,ko01000 - - - Pep_deformylase k141_4913_3 1453501.JELR01000002_gene1095 6.97e-146 425.0 COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,1RPJE@1236|Gammaproteobacteria,465H4@72275|Alteromonadaceae 1236|Gammaproteobacteria LU Rossmann fold nucleotide-binding protein involved in DNA uptake smf - - ko:K04096 - - - - ko00000 - - - DNA_processg_A k141_4913_4 1279017.AQYJ01000027_gene1766 3.16e-106 308.0 COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,1S3VN@1236|Gammaproteobacteria,466US@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) purE - 5.4.99.18 ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07405 RC01947 ko00000,ko00001,ko00002,ko01000 - - - AIRC k141_4913_5 1279017.AQYJ01000027_gene1765 6.64e-98 288.0 COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,1S610@1236|Gammaproteobacteria,4677N@72275|Alteromonadaceae 1236|Gammaproteobacteria J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-) CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate tsaC GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061710,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87 ko:K07566 - - R10463 RC00745 ko00000,ko01000,ko03009,ko03016 - - - Sua5_yciO_yrdC k141_36987_1 218284.CCDN010000006_gene3513 3.44e-91 276.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,1ZBKX@1386|Bacillus 91061|Bacilli I Belongs to the thiolase family fadA - 2.3.1.16 ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 M00087,M00113 R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095 RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955 ko00000,ko00001,ko00002,ko01000 - - - Thiolase_C,Thiolase_N k141_19164_1 997296.PB1_06917 2.42e-72 227.0 COG0515@1|root,COG0515@2|Bacteria,1TSNS@1239|Firmicutes,4HBDI@91061|Bacilli,1ZBVA@1386|Bacillus 91061|Bacilli KLT serine threonine protein kinase yabT - 2.7.11.1 ko:K08884 - - - - ko00000,ko01000,ko01001 - - - Pkinase k141_19164_2 218284.CCDN010000003_gene3000 6.36e-152 429.0 COG2304@1|root,COG2304@2|Bacteria,1U1SJ@1239|Firmicutes,4HD70@91061|Bacilli,1ZC1N@1386|Bacillus 91061|Bacilli S protein containing a von Willebrand factor type A (vWA) domain yabS - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - VWA,VWA_2 k141_3770_2 298655.KI912266_gene1232 4.22e-20 90.5 COG1091@1|root,COG1091@2|Bacteria,2GQ15@201174|Actinobacteria 201174|Actinobacteria M dTDP-4-dehydrorhamnose reductase - - 1.1.1.133 ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777 RC00182 ko00000,ko00001,ko00002,ko01000 - - - RmlD_sub_bind k141_6193_1 1211814.CAPG01000002_gene10 4.2e-46 152.0 COG4933@1|root,COG4933@2|Bacteria,1VBSE@1239|Firmicutes,4HMCX@91061|Bacilli 91061|Bacilli S ASCH domain - - - - - - - - - - - - ASCH k141_6193_2 1408303.JNJJ01000063_gene4838 3.67e-40 137.0 COG3153@1|root,COG3153@2|Bacteria,1V86H@1239|Firmicutes,4HJ51@91061|Bacilli,1ZI40@1386|Bacillus 91061|Bacilli S Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10,Acetyltransf_7 k141_27484_2 218284.CCDN010000001_gene1881 2.99e-83 255.0 COG0726@1|root,COG0726@2|Bacteria,1TQ5M@1239|Firmicutes,4HAHC@91061|Bacilli,1ZC6V@1386|Bacillus 91061|Bacilli G Sporulation protein, polysaccharide deacetylase ylxY GO:0005575,GO:0016020 - - - - - - - - - - Polysacc_deac_1 k141_3771_1 1116375.VEJY3_18241 2.67e-42 140.0 COG1359@1|root,COG1359@2|Bacteria,1N6P7@1224|Proteobacteria,1SF27@1236|Gammaproteobacteria,1XYY4@135623|Vibrionales 135623|Vibrionales S Antibiotic biosynthesis monooxygenase - - - - - - - - - - - - ABM k141_3771_2 1116375.VEJY3_18246 8.2e-65 204.0 COG0583@1|root,COG0583@2|Bacteria,1PX1B@1224|Proteobacteria,1SYEI@1236|Gammaproteobacteria,1XYEZ@135623|Vibrionales 135623|Vibrionales K COG0583 Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_247_1 441769.ABFU01000052_gene4120 2.53e-103 309.0 COG0192@1|root,COG0192@2|Bacteria,1TPCV@1239|Firmicutes,4HB33@91061|Bacilli,1ZBHR@1386|Bacillus 91061|Bacilli H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme metK GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 M00034,M00035,M00368,M00609 R00177,R04771 RC00021,RC01211 ko00000,ko00001,ko00002,ko01000 - - - S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N k141_25104_1 42565.FP66_07710 7.24e-73 228.0 COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,1RNZV@1236|Gammaproteobacteria,1XHXP@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) pdxA - 1.1.1.262 ko:K00097 ko00750,ko01100,map00750,map01100 M00124 R05681,R05837,R07406 RC00089,RC00675,RC01475 ko00000,ko00001,ko00002,ko01000 - - - PdxA k141_25104_2 42565.FP66_07715 1.26e-21 89.4 COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,1RMWU@1236|Gammaproteobacteria,1XICE@135619|Oceanospirillales 135619|Oceanospirillales M Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation surA - 5.2.1.8 ko:K03771 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_3,SurA_N k141_10828_1 866895.HBHAL_4602 3.6e-123 355.0 COG0356@1|root,COG0356@2|Bacteria,1TQIT@1239|Firmicutes,4H9NV@91061|Bacilli,3ND8Q@45667|Halobacillus 91061|Bacilli C it plays a direct role in the translocation of protons across the membrane atpB GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 - - ATP-synt_A k141_28757_1 1294265.JCM21738_2761 2.96e-88 261.0 COG0266@1|root,COG0266@2|Bacteria,1TPM9@1239|Firmicutes,4H9Q7@91061|Bacilli,1ZCC9@1386|Bacillus 91061|Bacilli L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates fpg - 3.2.2.23,4.2.99.18 ko:K10563 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Fapy_DNA_glyco,H2TH,zf-FPG_IleRS k141_29865_1 218284.CCDN010000001_gene1808 6.92e-86 276.0 COG0249@1|root,COG0249@2|Bacteria,1TPRJ@1239|Firmicutes,4HA63@91061|Bacilli,1ZB93@1386|Bacillus 91061|Bacilli L that it carries out the mismatch recognition step. This protein has a weak ATPase activity mutS GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K03555 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V k141_3772_1 1453501.JELR01000005_gene1589 2.67e-118 355.0 COG0366@1|root,COG0366@2|Bacteria,1MU90@1224|Proteobacteria,1RQ1S@1236|Gammaproteobacteria,465MB@72275|Alteromonadaceae 1236|Gammaproteobacteria G Alpha-amylase domain malS GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0004556,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009311,GO:0009313,GO:0009987,GO:0016052,GO:0016160,GO:0016787,GO:0016798,GO:0030288,GO:0030313,GO:0030978,GO:0030980,GO:0031975,GO:0042597,GO:0043167,GO:0043169,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044464,GO:0046872,GO:0051691,GO:0051692,GO:0071704,GO:1901575 3.2.1.1 ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 - R02108,R02112,R11262 - ko00000,ko00001,ko01000 - GH13 iECABU_c1320.ECABU_c40140,iECP_1309.ECP_3675,iECSE_1348.ECSE_3847,iPC815.YPO4080,ic_1306.c4392 Alpha-amylase k141_6195_1 589865.DaAHT2_1754 2.38e-17 79.0 COG1045@1|root,COG1045@2|Bacteria,1RM0T@1224|Proteobacteria,43APC@68525|delta/epsilon subdivisions 1224|Proteobacteria E Bacterial transferase hexapeptide (six repeats) - - 2.3.1.30 ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 M00021 R00586 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 - - - Hexapep k141_4914_1 218284.CCDN010000006_gene3519 6.48e-115 336.0 COG0506@1|root,COG0506@2|Bacteria,1TQV3@1239|Firmicutes,4HAC1@91061|Bacilli,1ZB5G@1386|Bacillus 91061|Bacilli E Proline dehydrogenase fadM GO:0000166,GO:0003674,GO:0003824,GO:0004657,GO:0005488,GO:0006082,GO:0006520,GO:0006560,GO:0006562,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016491,GO:0016645,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 - ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 - R10507 RC00083 ko00000,ko00001,ko01000 - - - Pro_dh k141_18067_1 218284.CCDN010000001_gene525 1.54e-87 265.0 COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,4HCZ7@91061|Bacilli,1ZCB1@1386|Bacillus 91061|Bacilli O HflC and HflK could encode or regulate a protease hflK - - ko:K04088 - M00742 - - ko00000,ko00002,ko01000 - - - Band_7 k141_18067_2 218284.CCDN010000001_gene524 1.85e-90 283.0 COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HB1B@91061|Bacilli,1ZC0T@1386|Bacillus 91061|Bacilli T Signal transduction histidine kinase phoR - 2.7.13.3 ko:K07636 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_9,sCache_like k141_12056_1 997346.HMPREF9374_2342 3.88e-08 55.1 COG1464@1|root,COG1464@2|Bacteria,1TQAS@1239|Firmicutes,4HBK0@91061|Bacilli,27BH2@186824|Thermoactinomycetaceae 91061|Bacilli P NLPA lipoprotein metQ - - ko:K02073 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - Lipoprotein_9 k141_12056_2 218284.CCDN010000006_gene3502 1.07e-138 394.0 COG2011@1|root,COG2011@2|Bacteria,1TR59@1239|Firmicutes,4H9NA@91061|Bacilli,1ZCW0@1386|Bacillus 91061|Bacilli P COG2011 ABC-type metal ion transport system, permease component metI GO:0000101,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0015711,GO:0015821,GO:0015849,GO:0016020,GO:0042940,GO:0044464,GO:0046942,GO:0048473,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0072348 - ko:K02069,ko:K02072 ko02010,map02010 M00211,M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24,9.B.25.1 - - BPD_transp_1 k141_12056_3 218284.CCDN010000006_gene3503 6.25e-199 556.0 COG1135@1|root,COG1135@2|Bacteria,1TPPN@1239|Firmicutes,4H9VX@91061|Bacilli,1ZAZX@1386|Bacillus 91061|Bacilli P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system metN GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0008150,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085 - ko:K02071 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - iYO844.BSU32750 ABC_tran,NIL k141_32213_1 1255043.TVNIR_3006 2.24e-150 443.0 COG4770@1|root,COG4770@2|Bacteria,1QYY8@1224|Proteobacteria,1RRCN@1236|Gammaproteobacteria 1236|Gammaproteobacteria I ATP-grasp domain - - - - - - - - - - - - ATP-grasp_4,CPSase_L_D2 k141_32213_2 1287116.X734_01895 1.64e-11 63.9 COG2936@1|root,COG2936@2|Bacteria,1MVA8@1224|Proteobacteria,2TU0R@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Hydrolase CocE NonD family - - - ko:K06978 - - - - ko00000 - - - PepX_C,Peptidase_S15 k141_7315_2 1116375.VEJY3_23896 1.4e-175 492.0 COG0583@1|root,COG0583@2|Bacteria,1PR6U@1224|Proteobacteria,1RQ7J@1236|Gammaproteobacteria,1XU53@135623|Vibrionales 135623|Vibrionales K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_7315_3 1116375.VEJY3_23891 1.27e-64 197.0 COG2076@1|root,COG2076@2|Bacteria,1MZ6P@1224|Proteobacteria,1S8TD@1236|Gammaproteobacteria,1XYEW@135623|Vibrionales 135623|Vibrionales P Small Multidrug Resistance protein sugE - - ko:K11741 - - - - ko00000,ko02000 2.A.7.1 - - Multi_Drug_Res k141_27486_1 218284.CCDN010000007_gene3911 3.39e-121 360.0 COG1292@1|root,COG1292@2|Bacteria,1TRS6@1239|Firmicutes,4HA7U@91061|Bacilli,1ZBRN@1386|Bacillus 91061|Bacilli M Belongs to the BCCT transporter (TC 2.A.15) family opuD_3 - - - - - - - - - - - BCCT k141_26372_2 1279017.AQYJ01000027_gene1846 4.64e-197 558.0 COG0477@1|root,COG2814@2|Bacteria,1MW19@1224|Proteobacteria,1RMSZ@1236|Gammaproteobacteria,464E9@72275|Alteromonadaceae 1236|Gammaproteobacteria EGP COG0477 Permeases of the major facilitator superfamily - - - ko:K07552 - - - - ko00000,ko02000 2.A.1.2 - - MFS_1 k141_8525_1 506534.Rhein_3043 9.34e-33 130.0 COG1629@1|root,COG4771@2|Bacteria,1MWKN@1224|Proteobacteria,1RMM6@1236|Gammaproteobacteria,1X0P0@135613|Chromatiales 135613|Chromatiales P TonB-dependent Receptor Plug - - - - - - - - - - - - Plug,TonB_dep_Rec k141_12057_1 218284.CCDN010000001_gene600 1.04e-101 306.0 COG0373@1|root,COG0373@2|Bacteria,1TQN9@1239|Firmicutes,4HAVC@91061|Bacilli,1ZBER@1386|Bacillus 91061|Bacilli H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) hemA - 1.2.1.70 ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R04109 RC00055,RC00149 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS08420 GlutR_N,GlutR_dimer,Shikimate_DH k141_15669_1 1196031.ALEG01000064_gene3548 2.51e-117 346.0 COG0773@1|root,COG0773@2|Bacteria,1TQ5H@1239|Firmicutes,4HAR4@91061|Bacilli,1ZB5U@1386|Bacillus 91061|Bacilli M Belongs to the MurCDEF family murC - 6.3.2.8 ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M k141_36988_1 1453501.JELR01000002_gene726 3.3e-111 328.0 COG2378@1|root,COG2378@2|Bacteria,1PXCX@1224|Proteobacteria,1RR3V@1236|Gammaproteobacteria,466P3@72275|Alteromonadaceae 1236|Gammaproteobacteria K WYL domain - - - - - - - - - - - - HTH_11,WYL k141_36988_2 685778.AORL01000001_gene181 5.02e-86 259.0 COG0625@1|root,COG0625@2|Bacteria,1RA05@1224|Proteobacteria,2TS58@28211|Alphaproteobacteria,2K1M0@204457|Sphingomonadales 204457|Sphingomonadales O Glutathione S-transferase - - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C,GST_C_2,GST_N,GST_N_3 k141_249_1 218284.CCDN010000001_gene695 5e-144 407.0 COG4122@1|root,COG4122@2|Bacteria,1UF4M@1239|Firmicutes,4HE9E@91061|Bacilli,1ZFK8@1386|Bacillus 91061|Bacilli S O-methyltransferase yrrM - 2.1.1.104 ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 M00039,M00350 R01942,R06578 RC00003,RC00392 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_3 k141_25107_1 401526.TcarDRAFT_2583 1.23e-05 52.8 COG3267@1|root,COG3267@2|Bacteria,1TRGM@1239|Firmicutes,4H7IJ@909932|Negativicutes 909932|Negativicutes U AAA domain - - - - - - - - - - - - AAA_22 k141_23919_2 1279017.AQYJ01000027_gene1607 1.19e-53 168.0 COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,1SCKA@1236|Gammaproteobacteria,46CD0@72275|Alteromonadaceae 1236|Gammaproteobacteria S RNA recognition motif - - - - - - - - - - - - RRM_1 k141_13294_1 218284.CCDN010000001_gene165 1.91e-117 351.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,1ZASV@1386|Bacillus 91061|Bacilli V COG1132 ABC-type multidrug transport system, ATPase and permease components yknU GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702 - ko:K06147,ko:K11085 ko02010,map02010 - - - ko00000,ko00001,ko01000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran k141_14480_1 218284.CCDN010000001_gene78 6.57e-130 377.0 COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,4H9WZ@91061|Bacilli,1ZC2F@1386|Bacillus 91061|Bacilli D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity ftsZ GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030428,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03531 ko04112,map04112 - - - ko00000,ko00001,ko02048,ko03036,ko04812 - - - FtsZ_C,Tubulin k141_2603_2 714961.BFZC1_19265 1.95e-24 94.7 COG0346@1|root,COG0346@2|Bacteria,1V422@1239|Firmicutes,4HH25@91061|Bacilli,3IY1D@400634|Lysinibacillus 91061|Bacilli H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor fosB GO:0003674,GO:0003824,GO:0004364,GO:0008150,GO:0016740,GO:0016765,GO:0042221,GO:0046677,GO:0050896 - ko:K11210,ko:K21252 - - - - ko00000,ko01000,ko01504 - - - Glyoxalase k141_12097_1 1042377.AFPJ01000014_gene1680 2.59e-13 68.6 COG1466@1|root,COG1466@2|Bacteria,1MWYT@1224|Proteobacteria,1RQRE@1236|Gammaproteobacteria,466B8@72275|Alteromonadaceae 1236|Gammaproteobacteria L DNA polymerase III, delta subunit holA GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delt_C,DNA_pol3_delta k141_31138_2 1042377.AFPJ01000037_gene2893 5.67e-132 386.0 COG4536@1|root,COG4536@2|Bacteria,1NZ99@1224|Proteobacteria,1RNCE@1236|Gammaproteobacteria,464AQ@72275|Alteromonadaceae 1236|Gammaproteobacteria P Mg2 and Co2 transporter CorB yfjD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - CBS,CorC_HlyC,DUF21 k141_1345_1 1122604.JONR01000015_gene196 3.48e-80 248.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RMMJ@1236|Gammaproteobacteria,1X56A@135614|Xanthomonadales 135614|Xanthomonadales I Acyl-CoA dehydrogenase - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_35811_2 218284.CCDN010000001_gene1174 1.88e-102 305.0 COG2897@1|root,COG2897@2|Bacteria,1TRYA@1239|Firmicutes,4HAQA@91061|Bacilli,1ZANF@1386|Bacillus 91061|Bacilli P sulfurtransferase sseA - 2.8.1.1,2.8.1.2 ko:K01011 ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122 - R01931,R03105,R03106 RC00214 ko00000,ko00001,ko01000 - - - Rhodanese k141_278_1 1123302.KB904186_gene784 1.07e-30 134.0 COG1404@1|root,COG1404@2|Bacteria,1TPH1@1239|Firmicutes,4HBQH@91061|Bacilli 91061|Bacilli O Belongs to the peptidase S8 family vpr GO:0005575,GO:0005576 3.4.21.96 ko:K01361,ko:K14647 ko02024,map02024 - - - ko00000,ko00001,ko01000,ko01002,ko03110 - - - FlgD_ig,Inhibitor_I9,PA,Peptidase_S8,SLH,fn3_5 k141_21631_1 1265313.HRUBRA_02318 1.43e-80 263.0 COG2937@1|root,COG2937@2|Bacteria,1MWZ6@1224|Proteobacteria,1RM7K@1236|Gammaproteobacteria,1J527@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria I Belongs to the GPAT DAPAT family plsB - 2.3.1.15 ko:K00631 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase k141_25145_1 218284.CCDN010000010_gene4373 1.67e-177 527.0 COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,4HA24@91061|Bacilli,1ZDK0@1386|Bacillus 91061|Bacilli K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoC GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 k141_13295_1 1158756.AQXQ01000012_gene1600 1.08e-38 145.0 COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,1RNMP@1236|Gammaproteobacteria,1WWCY@135613|Chromatiales 135613|Chromatiales G Synthesizes alpha-1,4-glucan chains using ADP-glucose glgA - 2.4.1.21 ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 M00565 R02421 RC00005 ko00000,ko00001,ko00002,ko01000,ko01003 - GT5 - Glyco_transf_5,Glycos_transf_1 k141_23949_1 218284.CCDN010000001_gene786 2.15e-96 291.0 COG0477@1|root,COG0477@2|Bacteria,1TTC8@1239|Firmicutes,4HAPZ@91061|Bacilli,1ZAQ7@1386|Bacillus 91061|Bacilli EGP Major facilitator superfamily yqgE - - ko:K08222 - - - - ko00000,ko02000 2.A.1.33 - - MFS_1 k141_25146_1 1307436.PBF_12172 8.33e-68 211.0 COG0406@1|root,COG0406@2|Bacteria,1V7F8@1239|Firmicutes,4HIR1@91061|Bacilli,1ZHAP@1386|Bacillus 91061|Bacilli G Phosphoglycerate mutase gpmA1 - 5.4.2.11 ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - His_Phos_1 k141_4923_1 1397528.Q671_01270 4.86e-107 325.0 COG3243@1|root,COG3243@2|Bacteria,1MU68@1224|Proteobacteria,1RPVQ@1236|Gammaproteobacteria,1XI1K@135619|Oceanospirillales 135619|Oceanospirillales I Poly(3-hydroxyalkanoate) synthetase - - - ko:K03821 ko00650,map00650 - R04254 RC00004 ko00000,ko00001,ko01000 - - - Abhydrolase_1,PhaC_N k141_37002_1 1123054.KB907738_gene3518 1.81e-78 246.0 COG2367@1|root,COG2367@2|Bacteria,1MZ00@1224|Proteobacteria,1S835@1236|Gammaproteobacteria 1236|Gammaproteobacteria V Beta-lactamase enzyme family - - - - - - - - - - - - Beta-lactamase2 k141_14481_1 218284.CCDN010000002_gene2838 4.94e-130 381.0 COG0277@1|root,COG0277@2|Bacteria,1TPBC@1239|Firmicutes,4H9UU@91061|Bacilli,1ZCQN@1386|Bacillus 91061|Bacilli C Glycolate oxidase subunit glcD - 1.1.3.15 ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001,ko01000 - - iYO844.BSU28680 FAD-oxidase_C,FAD_binding_4 k141_25147_1 935837.JAEK01000025_gene1571 1.81e-65 211.0 2ETXK@1|root,33MES@2|Bacteria,1VMD8@1239|Firmicutes,4HRHW@91061|Bacilli,1ZAQE@1386|Bacillus 91061|Bacilli S Spore germination protein - - - - - - - - - - - - Spore_permease k141_12100_1 1294265.JCM21738_4893 1.09e-106 311.0 COG2070@1|root,COG2070@2|Bacteria,1TPX1@1239|Firmicutes,4HK76@91061|Bacilli,1ZQDT@1386|Bacillus 91061|Bacilli S COG2070 Dioxygenases related to 2-nitropropane dioxygenase - - - - - - - - - - - - NMO k141_2604_1 223926.28806631 2.11e-165 465.0 COG0561@1|root,COG0561@2|Bacteria,1MXIH@1224|Proteobacteria,1SZZN@1236|Gammaproteobacteria,1Y2EQ@135623|Vibrionales 135623|Vibrionales S Sucrose-6F-phosphate phosphohydrolase - - - - - - - - - - - - Hydrolase_3 k141_23950_1 218284.CCDN010000002_gene2223 9.15e-122 362.0 COG0840@1|root,COG0840@2|Bacteria,1V0SD@1239|Firmicutes,4HD8P@91061|Bacilli,1ZCT0@1386|Bacillus 91061|Bacilli NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - MCPsignal k141_4924_1 1196031.ALEG01000039_gene1065 9.5e-49 157.0 COG0393@1|root,COG0393@2|Bacteria,1VADM@1239|Firmicutes,4HKFQ@91061|Bacilli,1ZH9U@1386|Bacillus 91061|Bacilli S Belongs to the UPF0145 family - - - - - - - - - - - - YbjQ_1 k141_21633_1 762948.HMPREF0733_10222 2.92e-29 112.0 COG2020@1|root,COG2020@2|Bacteria,2HKQR@201174|Actinobacteria,1WC7P@1268|Micrococcaceae 201174|Actinobacteria O Phospholipid methyltransferase - - - - - - - - - - - - PEMT k141_19179_2 1279017.AQYJ01000029_gene3646 1.06e-26 108.0 COG1506@1|root,COG1506@2|Bacteria,1MUJ3@1224|Proteobacteria,1RRN4@1236|Gammaproteobacteria,465BC@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases pqqM - - - - - - - - - - - PD40,Peptidase_S9 k141_13297_1 398511.BpOF4_01090 5.04e-08 50.8 2DCHH@1|root,2ZE6P@2|Bacteria,1W1JY@1239|Firmicutes,4I1E0@91061|Bacilli 91061|Bacilli S Protein of unknown function (Tiny_TM_bacill) - - - - - - - - - - - - Tiny_TM_bacill k141_20347_1 377629.TERTU_2066 1.14e-160 475.0 COG4631@1|root,COG4631@2|Bacteria,1NQSR@1224|Proteobacteria,1T1HI@1236|Gammaproteobacteria,2PPB9@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain xdhB - 1.17.1.4 ko:K13482 ko00230,ko01100,ko01120,map00230,map01100,map01120 M00546 R01768,R02103 RC00143 ko00000,ko00001,ko00002,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 k141_25148_1 42565.FP66_06615 2.36e-44 148.0 COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,1RQ38@1236|Gammaproteobacteria,1XI4I@135619|Oceanospirillales 135619|Oceanospirillales J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit rpsD - - ko:K02986 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S4,S4 k141_1346_1 406124.ACPC01000008_gene1675 8.71e-101 301.0 COG1349@1|root,COG1349@2|Bacteria,1V27B@1239|Firmicutes,4HGDW@91061|Bacilli,1ZFQZ@1386|Bacillus 91061|Bacilli K DeoR C terminal sensor domain - - - - - - - - - - - - DeoRC,HTH_DeoR k141_33454_1 1191299.AJYX01000051_gene1310 4.38e-17 79.0 COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,1RMDH@1236|Gammaproteobacteria,1XTP5@135623|Vibrionales 135623|Vibrionales H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III hemE - 4.1.1.37 ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03197,R04972 RC00872 ko00000,ko00001,ko00002,ko01000 - - - URO-D k141_33454_2 1280001.BAOA01000066_gene2724 6.8e-133 377.0 COG1573@1|root,COG1573@2|Bacteria,1R9XV@1224|Proteobacteria,1S20R@1236|Gammaproteobacteria,1XVHC@135623|Vibrionales 135623|Vibrionales L COG1573 Uracil-DNA glycosylase - - - - - - - - - - - - UDG k141_33454_3 1116375.VEJY3_14735 5.63e-57 184.0 COG0111@1|root,COG0111@2|Bacteria,1MW1U@1224|Proteobacteria,1RRQE@1236|Gammaproteobacteria,1XT3B@135623|Vibrionales 135623|Vibrionales EH COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases - - - - - - - - - - - - 2-Hacid_dh_C k141_32222_2 1116375.VEJY3_02740 1.4e-109 316.0 COG1076@1|root,COG1076@2|Bacteria,1RHZX@1224|Proteobacteria,1S9YH@1236|Gammaproteobacteria,1XTU9@135623|Vibrionales 135623|Vibrionales O Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA hscB GO:0006457,GO:0008150,GO:0009987 - ko:K04082 - - - - ko00000,ko03029,ko03110 - - - DnaJ,HSCB_C k141_32222_3 1116375.VEJY3_02735 3.3e-71 214.0 COG0316@1|root,COG0316@2|Bacteria,1RH6T@1224|Proteobacteria,1S5XD@1236|Gammaproteobacteria,1XXFW@135623|Vibrionales 135623|Vibrionales C Is able to transfer iron-sulfur clusters to apo- ferredoxin. Multiple cycles of 2Fe2S cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system iscA - - ko:K13628 - - - - ko00000,ko03016 - - - Fe-S_biosyn k141_32222_4 945550.VISI1226_15871 6.16e-85 250.0 COG0822@1|root,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,1S3P1@1236|Gammaproteobacteria,1XWW7@135623|Vibrionales 135623|Vibrionales C A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters iscU - - ko:K04488 - - - - ko00000 - - - NifU_N k141_17039_1 1453501.JELR01000001_gene2045 7.47e-119 348.0 COG2103@1|root,COG2103@2|Bacteria,1MVDR@1224|Proteobacteria,1RN3P@1236|Gammaproteobacteria,465RM@72275|Alteromonadaceae 1236|Gammaproteobacteria G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling murQ - 4.2.1.126 ko:K07106 ko00520,ko01100,map00520,map01100 - R08555 RC00397,RC00746 ko00000,ko00001,ko01000 - - - SIS,SIS_2 k141_25387_1 218284.CCDN010000001_gene976 2.95e-91 272.0 COG0745@1|root,COG0745@2|Bacteria,1TPF7@1239|Firmicutes,4HA1M@91061|Bacilli,1ZBNB@1386|Bacillus 91061|Bacilli KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process spo0A GO:0000003,GO:0000156,GO:0000160,GO:0000910,GO:0003674,GO:0006355,GO:0007049,GO:0007154,GO:0007165,GO:0008150,GO:0008356,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016043,GO:0019219,GO:0019222,GO:0019954,GO:0022402,GO:0022603,GO:0022607,GO:0023052,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0032506,GO:0035556,GO:0042173,GO:0042710,GO:0043934,GO:0043937,GO:0043938,GO:0044010,GO:0044085,GO:0044764,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051171,GO:0051252,GO:0051301,GO:0051704,GO:0051716,GO:0060089,GO:0060255,GO:0065007,GO:0071840,GO:0080090,GO:0090529,GO:0090604,GO:0090606,GO:1903506,GO:2000112,GO:2001141 - ko:K07699 ko02020,ko02024,map02020,map02024 M00485 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Spo0A_C k141_4051_1 218284.CCDN010000007_gene3890 9.03e-120 346.0 COG1011@1|root,COG1011@2|Bacteria,1TQYM@1239|Firmicutes,4HFDW@91061|Bacilli,1ZFZB@1386|Bacillus 91061|Bacilli S Haloacid dehalogenase-like hydrolase - - 3.8.1.2 ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 - R05287 RC00697 ko00000,ko00001,ko01000 - - - HAD_2 k141_7487_1 1279017.AQYJ01000023_gene3293 2.15e-79 263.0 COG3525@1|root,COG3525@2|Bacteria,1MVDE@1224|Proteobacteria,1RMNI@1236|Gammaproteobacteria,465K7@72275|Alteromonadaceae 1236|Gammaproteobacteria G Putative carbohydrate binding domain chb - 3.2.1.52 ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 M00079 R00022,R06004,R11316 RC00049 ko00000,ko00001,ko00002,ko01000,ko03110 - GH20 - CHB_HEX,CHB_HEX_C,Glyco_hydro_20,Glyco_hydro_20b k141_20550_1 218284.CCDN010000001_gene1007 2.48e-20 89.0 COG0364@1|root,COG0364@2|Bacteria,1TPYF@1239|Firmicutes,4HA73@91061|Bacilli,1ZCZ3@1386|Bacillus 91061|Bacilli G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone zwf - 1.1.1.363,1.1.1.49 ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 M00004,M00006,M00008 R00835,R02736,R10907 RC00001,RC00066 ko00000,ko00001,ko00002,ko01000,ko04147 - - - G6PD_C,G6PD_N k141_30033_1 1266909.AUAG01000001_gene1479 1.39e-10 67.0 COG0859@1|root,COG0859@2|Bacteria,1MYZA@1224|Proteobacteria,1RR6K@1236|Gammaproteobacteria,1X2HB@135613|Chromatiales 135613|Chromatiales M Glycosyltransferase family 9 (heptosyltransferase) - - - ko:K02849 ko00540,ko01100,map00540,map01100 M00080 - - ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT9 - Glyco_transf_9 k141_9966_1 1294265.JCM21738_184 4.62e-22 95.1 COG0116@1|root,COG0116@2|Bacteria,1TP0X@1239|Firmicutes,4HBKY@91061|Bacilli,1ZBJB@1386|Bacillus 91061|Bacilli L Belongs to the methyltransferase superfamily ypsC GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 - ko:K07444 - - - - ko00000,ko01000 - - - THUMP,UPF0020 k141_20575_2 1116375.VEJY3_07725 2.2e-54 170.0 COG1254@1|root,COG1254@2|Bacteria,1N6NU@1224|Proteobacteria,1SCPF@1236|Gammaproteobacteria,1XYDK@135623|Vibrionales 135623|Vibrionales C COG1254 Acylphosphatases acyP GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 - R00317,R01421,R01515 RC00043 ko00000,ko00001,ko01000 - - - Acylphosphatase k141_542_1 218284.CCDN010000008_gene4198 8.27e-119 360.0 COG1523@1|root,COG1523@2|Bacteria,1TP3M@1239|Firmicutes,4HBP5@91061|Bacilli,1ZC85@1386|Bacillus 91061|Bacilli G Belongs to the glycosyl hydrolase 13 family amyX - 3.2.1.41 ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 - R02111 - ko00000,ko00001,ko01000 - CBM48,GH13 - Alpha-amylase,CBM_48 k141_11136_1 218284.CCDN010000002_gene2710 6.82e-57 178.0 COG1393@1|root,COG1393@2|Bacteria,1V3QC@1239|Firmicutes,4HH0I@91061|Bacilli,1ZGP8@1386|Bacillus 91061|Bacilli K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress spxA - - ko:K16509 - - - - ko00000 - - - ArsC k141_25423_1 218284.CCDN010000006_gene3621 7.19e-184 538.0 COG0745@1|root,COG5000@1|root,COG5002@1|root,COG0745@2|Bacteria,COG5000@2|Bacteria,COG5002@2|Bacteria,1U7NI@1239|Firmicutes,4HA3E@91061|Bacilli,1ZCFX@1386|Bacillus 91061|Bacilli T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - GAF,GAF_3,HAMP,HATPase_c,HisKA,Response_reg k141_4062_1 1279017.AQYJ01000018_gene825 2.79e-89 282.0 COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,1RNM8@1236|Gammaproteobacteria,4656A@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family fadH - 1.3.1.34 ko:K00219 - - - - ko00000,ko01000 - - - Oxidored_FMN,Pyr_redox_2 k141_26769_1 1385514.N782_00365 2.6e-105 316.0 COG0659@1|root,COG0659@2|Bacteria,1TT9Y@1239|Firmicutes,4HDPJ@91061|Bacilli,2YBGY@289201|Pontibacillus 91061|Bacilli P Psort location CytoplasmicMembrane, score - - - - - - - - - - - - Xan_ur_permease k141_9967_1 1294265.JCM21738_4009 6.02e-42 142.0 COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,4HBK9@91061|Bacilli,1ZMXW@1386|Bacillus 91061|Bacilli I Carboxyl transferase domain yngE - - - - - - - - - - iYO844.BSU18210 Carboxyl_trans k141_9967_2 1294265.JCM21738_4008 8.02e-21 84.3 COG1038@1|root,COG1038@2|Bacteria,1UIWR@1239|Firmicutes,4ISV0@91061|Bacilli,1ZS6P@1386|Bacillus 91061|Bacilli C Biotin carboxyl carrier protein yngHB - - ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742 RC00040,RC00367 ko00000,ko00001,ko00002 - - - Biotin_lipoyl k141_9967_3 1294265.JCM21738_4007 1.32e-11 63.5 COG0439@1|root,COG0439@2|Bacteria,1TP16@1239|Firmicutes,4HA40@91061|Bacilli,1ZBTG@1386|Bacillus 91061|Bacilli I Biotin carboxylase accC2 - 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 k141_5179_1 543728.Vapar_2417 3.21e-13 72.0 COG3469@1|root,COG3509@1|root,COG3469@2|Bacteria,COG3509@2|Bacteria,1NTIV@1224|Proteobacteria,2VKDX@28216|Betaproteobacteria,4ACW5@80864|Comamonadaceae 28216|Betaproteobacteria Q PFAM Fibronectin type III domain protein phaZ - 3.1.1.75 ko:K05973 ko00650,map00650 - R05118 - ko00000,ko00001,ko01000 - - - Esterase_phd,fn3 k141_5179_2 935839.JAGJ01000010_gene310 5.36e-70 233.0 COG2234@1|root,COG3509@1|root,COG2234@2|Bacteria,COG3509@2|Bacteria,2I0Q0@201174|Actinobacteria,4F57Q@85017|Promicromonosporaceae 201174|Actinobacteria Q Esterase PHB depolymerase - - - - - - - - - - - - Esterase_phd k141_27623_1 218284.CCDN010000001_gene1075 5.33e-09 55.8 COG3547@1|root,COG3547@2|Bacteria,1TQ5G@1239|Firmicutes,4HB35@91061|Bacilli,1ZCUW@1386|Bacillus 91061|Bacilli L COG3547 Transposase and inactivated derivatives - - - ko:K07486 - - - - ko00000 - - - DEDD_Tnp_IS110,Transposase_20 k141_25424_2 1042377.AFPJ01000051_gene41 4.28e-11 59.7 2DEP1@1|root,32U3R@2|Bacteria,1N4PQ@1224|Proteobacteria,1S83R@1236|Gammaproteobacteria,4696P@72275|Alteromonadaceae 1236|Gammaproteobacteria S Type VIII secretion system (T8SS), CsgF protein - - - ko:K04338 - - - - ko00000,ko02044 - - - CsgF k141_11137_1 218284.CCDN010000001_gene1875 7.2e-33 124.0 COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,4HADX@91061|Bacilli,1ZBSQ@1386|Bacillus 91061|Bacilli E Belongs to the aspartokinase family dapG GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,ACT_7 k141_11137_2 218284.CCDN010000001_gene1874 1.31e-97 290.0 COG0329@1|root,COG0329@2|Bacteria,1TPCK@1239|Firmicutes,4H9K9@91061|Bacilli,1ZBNR@1386|Bacillus 91061|Bacilli E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) dapA - 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS k141_32399_1 1042377.AFPJ01000028_gene2299 1.52e-66 206.0 COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,1RN09@1236|Gammaproteobacteria,466I4@72275|Alteromonadaceae 1236|Gammaproteobacteria F Essential for recycling GMP and indirectly, cGMP gmk GO:0003674,GO:0003824,GO:0004385,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_2813,iPC815.YPO0040,iSBO_1134.SBO_3729,iSFV_1184.SFV_3881,iSFxv_1172.SFxv_4016,iUTI89_1310.UTI89_C4193 Guanylate_kin k141_12447_1 218284.CCDN010000001_gene1395 1.41e-126 372.0 COG1396@1|root,COG1396@2|Bacteria,1U4VN@1239|Firmicutes,4HE98@91061|Bacilli,1ZDJQ@1386|Bacillus 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - ko:K20480 ko02024,map02024 - - - ko00000,ko00001,ko03000 - - - HTH_3,TPR_12,TPR_7,TPR_8 k141_37200_1 1294265.JCM21738_1924 2.63e-232 644.0 COG4469@1|root,COG4469@2|Bacteria,1TRGD@1239|Firmicutes,4HFP5@91061|Bacilli,1ZCFD@1386|Bacillus 91061|Bacilli S Competence protein coiA - - ko:K06198 - - - - ko00000 - - - CoiA k141_37200_2 1294265.JCM21738_1923 6.75e-52 178.0 COG1164@1|root,COG1164@2|Bacteria,1TP4P@1239|Firmicutes,4HA7X@91061|Bacilli,1ZCHA@1386|Bacillus 91061|Bacilli E oligoendopeptidase F pepF GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - ko:K08602 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M3,Peptidase_M3_N k141_8813_1 10753.DPOL_BPNF 5.51e-106 323.0 4QAWD@10239|Viruses,4QVNG@35237|dsDNA viruses no RNA stage,4QQCM@28883|Caudovirales,4QNB7@10744|Podoviridae 10744|Podoviridae S nucleotide binding - - - - - - - - - - - - - k141_18313_1 218284.CCDN010000001_gene1159 1.86e-40 148.0 COG3359@1|root,COG3359@2|Bacteria,1TQQU@1239|Firmicutes,4HDMU@91061|Bacilli,1ZAZQ@1386|Bacillus 91061|Bacilli L RNase_H superfamily yprB - - ko:K07502 - - - - ko00000 - - - RNase_H_2 k141_5180_1 406124.ACPC01000005_gene3522 9.92e-68 216.0 COG4214@1|root,COG4214@2|Bacteria,1VU1F@1239|Firmicutes,4HBDM@91061|Bacilli,1ZQAE@1386|Bacillus 91061|Bacilli G Belongs to the binding-protein-dependent transport system permease family - - - ko:K10544,ko:K10547 ko02010,map02010 M00215,M00216 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.4,3.A.1.2.5 - - BPD_transp_2 k141_5180_2 406124.ACPC01000005_gene3523 9.75e-16 75.9 COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,4H9VK@91061|Bacilli,1ZB07@1386|Bacillus 91061|Bacilli G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system - - 3.6.3.17 ko:K10548 ko02010,map02010 M00216 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.2.5 - - ABC_tran k141_7499_1 1279017.AQYJ01000026_gene66 2.58e-129 389.0 COG0457@1|root,COG0457@2|Bacteria,1MXSS@1224|Proteobacteria,1S157@1236|Gammaproteobacteria,46CPY@72275|Alteromonadaceae 1236|Gammaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16 k141_7499_2 443144.GM21_0437 1.8e-20 87.8 2B4XH@1|root,32REP@2|Bacteria,1PXEZ@1224|Proteobacteria,4305C@68525|delta/epsilon subdivisions,2WVH5@28221|Deltaproteobacteria,43UUP@69541|Desulfuromonadales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k141_543_2 1288826.MSNKSG1_00546 9.37e-36 123.0 2E70X@1|root,331JP@2|Bacteria,1N81S@1224|Proteobacteria,1SCI0@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - ko:K02116 - - - - ko00000,ko00194 3.A.2.1 - - ATPase_gene1 k141_25425_1 218284.CCDN010000001_gene1489 2.22e-131 395.0 COG0188@1|root,COG0188@2|Bacteria,1TRE7@1239|Firmicutes,4HAQB@91061|Bacilli,1ZBCI@1386|Bacillus 91061|Bacilli L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K02621 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseA_C,DNA_topoisoIV k141_23086_1 1265503.KB905173_gene4135 8.92e-72 226.0 COG1943@1|root,COG1943@2|Bacteria,1MVUV@1224|Proteobacteria,1RNIV@1236|Gammaproteobacteria 1236|Gammaproteobacteria L COG1943 Transposase and inactivated derivatives - - - - - - - - - - - - - k141_18314_1 1294265.JCM21738_1422 2.41e-23 95.1 COG2362@1|root,COG2362@2|Bacteria,1TSUZ@1239|Firmicutes,4HC5R@91061|Bacilli,1ZC41@1386|Bacillus 91061|Bacilli E D-aminopeptidase dppA - - ko:K16203 - - - - ko00000,ko01000,ko01002 3.A.1.5.2 - iYO844.BSU12920 Peptidase_M55 k141_18314_2 1403313.AXBR01000005_gene1878 4.57e-15 72.4 COG0494@1|root,COG0494@2|Bacteria,1V6SF@1239|Firmicutes,4HG46@91061|Bacilli,1ZB2X@1386|Bacillus 91061|Bacilli L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes XK27_06885 - - - - - - - - - - - NUDIX k141_8814_1 1005994.GTGU_01629 5.37e-10 61.2 COG3940@1|root,COG3940@2|Bacteria,1NKF0@1224|Proteobacteria,1RNIH@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Belongs to the glycosyl hydrolase 43 family abf2 - - - - - - - - - - - Glyco_hydro_43 k141_8814_2 1134474.O59_001174 1.75e-14 73.2 COG3507@1|root,COG3507@2|Bacteria,1R3V6@1224|Proteobacteria,1RPI5@1236|Gammaproteobacteria,1FGEF@10|Cellvibrio 1236|Gammaproteobacteria G Glycosyl hydrolases family 43 abnA - 3.2.1.99 ko:K06113 - - - - ko00000,ko01000 - GH43 - Glyco_hydro_43 k141_27624_1 218284.CCDN010000001_gene1339 3.47e-73 228.0 COG0454@1|root,COG0456@2|Bacteria 2|Bacteria K acetyltransferase - - - ko:K18566 ko00332,ko01130,map00332,map01130 - R10745,R10746 RC00004,RC00096 ko00000,ko00001,ko01000 - - - Acetyltransf_1 k141_12448_1 218284.CCDN010000009_gene4311 2.47e-169 473.0 COG3403@1|root,COG3403@2|Bacteria,1US5K@1239|Firmicutes,4HEQ9@91061|Bacilli,1ZDEK@1386|Bacillus 91061|Bacilli S YqcI/YcgG family - - - ko:K09190 - - - - ko00000 - - - YqcI_YcgG k141_34866_1 195250.CM001776_gene1096 1.08e-75 239.0 COG0156@1|root,COG0156@2|Bacteria,1FZY9@1117|Cyanobacteria,1GZBX@1129|Synechococcus 1117|Cyanobacteria E Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide bioF - 2.3.1.29,2.3.1.47 ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 M00123,M00573,M00577 R00371,R03210,R10124 RC00004,RC00039,RC00394,RC02725 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k141_33742_1 1340434.AXVA01000003_gene1778 1.2e-135 392.0 COG0820@1|root,COG0820@2|Bacteria,1TPVF@1239|Firmicutes,4H9NU@91061|Bacilli,1ZBCJ@1386|Bacillus 91061|Bacilli J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs rlmN GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 ko:K06941 - - - - ko00000,ko01000,ko03009 - - - Fer4_14,Radical_SAM k141_5182_1 218284.CCDN010000002_gene2016 3.28e-113 337.0 COG0064@1|root,COG0064@2|Bacteria,1TPG3@1239|Firmicutes,4HAFB@91061|Bacilli,1ZB3K@1386|Bacillus 91061|Bacilli J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatB GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 ko:K02434 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - GatB_N,GatB_Yqey k141_1548_1 1279017.AQYJ01000021_gene2944 1.76e-122 365.0 COG0028@1|root,COG0028@2|Bacteria,1MWVW@1224|Proteobacteria,1RPZ2@1236|Gammaproteobacteria,465G8@72275|Alteromonadaceae 1236|Gammaproteobacteria EH Thiamine pyrophosphate enzyme, central domain - - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N k141_35985_1 1042377.AFPJ01000032_gene2830 4.99e-104 326.0 COG2959@1|root,COG2959@2|Bacteria,1MY3A@1224|Proteobacteria,1RNJY@1236|Gammaproteobacteria,467C6@72275|Alteromonadaceae 1236|Gammaproteobacteria H enzyme of heme biosynthesis hemX - 2.1.1.107,4.2.1.75 ko:K02496,ko:K13543 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R03165,R03194 RC00003,RC00871,RC01861 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b3803,iBWG_1329.BWG_3482,iECDH1ME8569_1439.ECDH1ME8569_3682,iECUMN_1333.ECUMN_4327,iECs_1301.ECs4733,iEcDH1_1363.EcDH1_4176,iJO1366.b3803,iJR904.b3803,iPC815.YPO3851,iUMN146_1321.UM146_19140,iY75_1357.Y75_RS18060,iZ_1308.Z5317 HemX k141_35985_2 1279017.AQYJ01000027_gene1601 1.54e-99 298.0 COG1587@1|root,COG1587@2|Bacteria,1MWZD@1224|Proteobacteria,1RM9K@1236|Gammaproteobacteria,467BQ@72275|Alteromonadaceae 1236|Gammaproteobacteria H COG1587 Uroporphyrinogen-III synthase hemD GO:0003674,GO:0003824,GO:0004852,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.75 ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R03165 RC01861 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_0187,iSBO_1134.SBO_3815 HEM4 k141_35985_3 76869.PputGB1_0211 1.54e-74 233.0 COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,1RMQ8@1236|Gammaproteobacteria,1YWEQ@136845|Pseudomonas putida group 1236|Gammaproteobacteria H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps hemC GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018065,GO:0018130,GO:0018160,GO:0018193,GO:0018198,GO:0019438,GO:0019538,GO:0033013,GO:0033014,GO:0034641,GO:0036211,GO:0042168,GO:0042440,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00084 RC02317 ko00000,ko00001,ko00002,ko01000 - - iEC55989_1330.EC55989_4275,iECH74115_1262.ECH74115_5243,iECIAI1_1343.ECIAI1_3991,iECO103_1326.ECO103_4362,iECO111_1330.ECO111_4628,iECO26_1355.ECO26_4784,iECSE_1348.ECSE_4086,iEKO11_1354.EKO11_4554,iPC815.YPO3849 Porphobil_deam,Porphobil_deamC k141_4063_1 218284.CCDN010000001_gene930 1.54e-130 382.0 COG1459@1|root,COG1459@2|Bacteria,1U00C@1239|Firmicutes,4HGUA@91061|Bacilli,1ZCQK@1386|Bacillus 91061|Bacilli NU COG1459 Type II secretory pathway, component PulF comGB - - ko:K02244 - M00429 - - ko00000,ko00002,ko02044 3.A.14.1 - - T2SSF k141_12450_1 218284.CCDN010000006_gene3621 1.99e-95 305.0 COG0745@1|root,COG5000@1|root,COG5002@1|root,COG0745@2|Bacteria,COG5000@2|Bacteria,COG5002@2|Bacteria,1U7NI@1239|Firmicutes,4HA3E@91061|Bacilli,1ZCFX@1386|Bacillus 91061|Bacilli T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - GAF,GAF_3,HAMP,HATPase_c,HisKA,Response_reg k141_545_1 1416759.AYMR01000044_gene3910 9.27e-08 58.2 COG1409@1|root,COG3227@1|root,COG4932@1|root,COG1409@2|Bacteria,COG3227@2|Bacteria,COG4932@2|Bacteria,2GP0C@201174|Actinobacteria,4FN6M@85023|Microbacteriaceae 201174|Actinobacteria E Purple acid Phosphatase, N-terminal domain - - - - - - - - - - - - CBM_6,DUF5011,Metallophos,Pur_ac_phosph_N k141_34867_2 1453501.JELR01000002_gene923 1.32e-30 108.0 COG3242@1|root,COG3242@2|Bacteria,1N9FC@1224|Proteobacteria,1SEP6@1236|Gammaproteobacteria,46965@72275|Alteromonadaceae 1236|Gammaproteobacteria S Uncharacterized protein conserved in bacteria (DUF2065) - - - ko:K09937 - - - - ko00000 - - - DUF2065 k141_21821_2 1294265.JCM21738_2950 8.01e-124 357.0 COG2267@1|root,COG2267@2|Bacteria,1UZ5S@1239|Firmicutes,4HEHP@91061|Bacilli,1ZBD1@1386|Bacillus 91061|Bacilli I Alpha beta hydrolase ytpA GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0008150,GO:0008152,GO:0016020,GO:0016298,GO:0016787,GO:0016788,GO:0044238,GO:0071704 3.1.1.5 ko:K01048 ko00564,map00564 - - - ko00000,ko00001,ko01000 - - - Hydrolase_4 k141_26770_1 1042377.AFPJ01000012_gene1387 5.06e-31 118.0 COG3346@1|root,COG3346@2|Bacteria,1MZUH@1224|Proteobacteria,1S8S0@1236|Gammaproteobacteria,4684Q@72275|Alteromonadaceae 1236|Gammaproteobacteria S SURF1-like protein surf1 - - ko:K14998 - - - - ko00000,ko03029 3.D.4.8 - - SURF1 k141_26770_2 1453501.JELR01000002_gene1069 4.14e-75 233.0 COG1999@1|root,COG1999@2|Bacteria,1N6R6@1224|Proteobacteria,1SC88@1236|Gammaproteobacteria,46868@72275|Alteromonadaceae 1236|Gammaproteobacteria S signal sequence binding - - - - - - - - - - - - - k141_26770_3 1453501.JELR01000002_gene1068 2.17e-194 545.0 COG1612@1|root,COG1612@2|Bacteria,1MVJ4@1224|Proteobacteria,1RQWB@1236|Gammaproteobacteria,463XT@72275|Alteromonadaceae 1236|Gammaproteobacteria O protein required for cytochrome oxidase assembly ctaA - - ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 M00154 R07412 RC00769 ko00000,ko00001,ko00002,ko03029 3.D.4.4 - - COX15-CtaA k141_9969_2 1042377.AFPJ01000043_gene826 3.97e-134 386.0 COG1028@1|root,COG1028@2|Bacteria,1MU5Y@1224|Proteobacteria,1RP7D@1236|Gammaproteobacteria,46633@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) bdhA - 1.1.1.30 ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 M00088 R01361 RC00117 ko00000,ko00001,ko00002,ko01000 - - - adh_short,adh_short_C2 k141_9969_3 1453501.JELR01000002_gene1385 9.66e-104 305.0 COG2197@1|root,COG2197@2|Bacteria,1PXTY@1224|Proteobacteria,1RMPW@1236|Gammaproteobacteria,466JI@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain agmR - - ko:K07684 ko02020,map02020 M00471 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg k141_9969_4 1453501.JELR01000002_gene1384 3.42e-12 65.9 COG0657@1|root,COG0657@2|Bacteria,1RD8A@1224|Proteobacteria,1S3TH@1236|Gammaproteobacteria,4687P@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG0657 Esterase lipase - - 3.1.1.83,3.1.1.85 ko:K14731,ko:K19561 ko00780,ko00903,ko00930,ko01100,ko01220,map00780,map00903,map00930,map01100,map01220 M00572 R03751,R06390,R06391,R06392,R06393,R09725 RC00460,RC00461,RC00713,RC00983,RC01505 ko00000,ko00001,ko00002,ko01000 - - - Abhydrolase_3 k141_7500_1 267748.MMOB2690 1.01e-19 87.4 COG4508@1|root,COG4508@2|Bacteria,3WTCQ@544448|Tenericutes 544448|Tenericutes S protein conserved in bacteria - - - - - - - - - - - - dUTPase_2 k141_8816_1 392500.Swoo_0177 2.58e-75 241.0 COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,1RPC3@1236|Gammaproteobacteria,2Q8HU@267890|Shewanellaceae 1236|Gammaproteobacteria C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B ctaD - 1.10.3.10,1.9.3.1 ko:K02274,ko:K02298 ko00190,ko01100,map00190,map01100 M00155,M00417 R00081,R11335 RC00016,RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.5,3.D.4.6 - iJN746.PP_0104 COX1 k141_8816_2 1123255.JHYS01000005_gene606 9.3e-05 45.4 COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,1MWHZ@1224|Proteobacteria,2VH9M@28216|Betaproteobacteria,4ABGS@80864|Comamonadaceae 28216|Betaproteobacteria C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) coxB - 1.9.3.1 ko:K02275 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.4,3.D.4.6 - - COX2,COX2_TM,Cytochrome_CBB3,OmpA k141_34868_1 997296.PB1_14249 1.77e-97 294.0 COG0755@1|root,COG0755@2|Bacteria,1TQZ4@1239|Firmicutes,4HA2N@91061|Bacilli,1ZBH9@1386|Bacillus 91061|Bacilli O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component' resC - - - - - - - - - - - Cytochrom_C_asm k141_14641_1 1333507.AUTQ01000275_gene2043 2.02e-60 191.0 COG0110@1|root,COG0110@2|Bacteria,1RA2T@1224|Proteobacteria,1S3ZZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S acetyltransferase, isoleucine patch superfamily maa GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008374,GO:0008925,GO:0009987,GO:0016043,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0022607,GO:0042802,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071840 2.3.1.79 ko:K00661 - - - - ko00000,ko01000 - - iAPECO1_1312.APECO1_15532,iECOK1_1307.ECOK1_0441,iECS88_1305.ECS88_0456,iUMN146_1321.UM146_15065,iUTI89_1310.UTI89_C0486 Hexapep,Hexapep_2,Mac k141_14641_2 404380.Gbem_1474 1.68e-44 154.0 COG2207@1|root,COG3449@1|root,COG2207@2|Bacteria,COG3449@2|Bacteria,1MWTF@1224|Proteobacteria,42RC6@68525|delta/epsilon subdivisions,2WN72@28221|Deltaproteobacteria 28221|Deltaproteobacteria K transcription activator, effector binding - - - ko:K13652 - - - - ko00000,ko03000 - - - GyrI-like,HTH_18 k141_28951_1 218284.CCDN010000005_gene3216 2.23e-122 353.0 COG2323@1|root,COG2323@2|Bacteria,1V57C@1239|Firmicutes,4HH3Q@91061|Bacilli,1ZCGW@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF421) - - - - - - - - - - - - DUF421 k141_37218_1 218284.CCDN010000002_gene2229 2.11e-129 392.0 COG5000@1|root,COG5002@1|root,COG5000@2|Bacteria,COG5002@2|Bacteria,1VS6X@1239|Firmicutes,4HV7W@91061|Bacilli,1ZS6R@1386|Bacillus 91061|Bacilli T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,dCache_1 k141_23109_1 1405.DJ92_1350 6.52e-113 332.0 COG1708@1|root,COG1708@2|Bacteria,1VB41@1239|Firmicutes,4HFDS@91061|Bacilli,1ZFGH@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF4037) - - - - - - - - - - - - DUF4037 k141_31306_1 1397528.Q671_00595 7e-78 247.0 COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,1RPNE@1236|Gammaproteobacteria,1XIUK@135619|Oceanospirillales 135619|Oceanospirillales I AMP-binding enzyme - - - - - - - - - - - - AMP-binding k141_564_1 218284.CCDN010000006_gene3553 6.65e-107 313.0 COG2220@1|root,COG2220@2|Bacteria,1TRRP@1239|Firmicutes,4HBBS@91061|Bacilli,1ZQZH@1386|Bacillus 91061|Bacilli S Beta-lactamase superfamily domain - - - - - - - - - - - - Lactamase_B_2 k141_36000_1 42565.FP66_10980 6.79e-55 187.0 COG3115@1|root,COG3115@2|Bacteria,1MVHR@1224|Proteobacteria,1RMDB@1236|Gammaproteobacteria,1XKA8@135619|Oceanospirillales 135619|Oceanospirillales D Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins zipA - - ko:K03528 - - - - ko00000,ko03036 - - - ZipA_C k141_25458_1 218284.CCDN010000001_gene575 4.35e-80 239.0 COG1719@1|root,COG1719@2|Bacteria,1VD7N@1239|Firmicutes,4HKV3@91061|Bacilli,1ZH1A@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2507) yslB - - - - - - - - - - - DUF2507 k141_19459_1 580340.Tlie_0338 2.29e-68 222.0 COG0591@1|root,COG0591@2|Bacteria,3TB7Q@508458|Synergistetes 508458|Synergistetes E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - ko:K03307 - - - - ko00000 2.A.21 - - SSF k141_26796_1 218284.CCDN010000002_gene2105 4.42e-263 723.0 COG0334@1|root,COG0334@2|Bacteria,1TR4Z@1239|Firmicutes,4HB4J@91061|Bacilli,1ZDBX@1386|Bacillus 91061|Bacilli E Glutamate/Leucine/Phenylalanine/Valine dehydrogenase - - 1.4.1.20 ko:K00270 ko00350,ko00360,ko00400,ko01100,ko01110,ko01130,map00350,map00360,map00400,map01100,map01110,map01130 - R00688,R09830 RC00006 ko00000,ko00001,ko01000 - - - ELFV_dehydrog,ELFV_dehydrog_N k141_2775_1 1279017.AQYJ01000024_gene947 1.05e-35 130.0 2A65Z@1|root,30UYE@2|Bacteria,1RDBP@1224|Proteobacteria,1S5Q6@1236|Gammaproteobacteria,46AZ0@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_4077_1 1279017.AQYJ01000024_gene1153 2.18e-06 47.4 COG3070@1|root,COG3070@2|Bacteria,1NAYG@1224|Proteobacteria,1SDXZ@1236|Gammaproteobacteria,46BQS@72275|Alteromonadaceae 1236|Gammaproteobacteria K TfoX N-terminal domain - - - - - - - - - - - - TfoX_N k141_4077_2 1042377.AFPJ01000042_gene1073 1.57e-131 397.0 COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,1RNCM@1236|Gammaproteobacteria,464B9@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs iorB - 1.3.99.16 ko:K07303 - - - - ko00000,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2,TAT_signal k141_12480_1 1232683.ADIMK_1377 1.33e-55 181.0 COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,1RR4F@1236|Gammaproteobacteria,465JZ@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG2801 Transposase and inactivated derivatives - - - ko:K07497 - - - - ko00000 - - - HTH_21,rve k141_33766_1 1283337.B0ZSI4_BPHA1 6.81e-113 358.0 4QAY9@10239|Viruses,4QUV8@35237|dsDNA viruses no RNA stage,4QPFD@28883|Caudovirales,4QIII@10662|Myoviridae 10662|Myoviridae S hydrolase activity, acting on acid anhydrides - - - - - - - - - - - - - k141_11170_2 218284.CCDN010000001_gene1114 4.9e-169 479.0 COG0082@1|root,COG0082@2|Bacteria,1TQ40@1239|Firmicutes,4HA0H@91061|Bacilli,1ZB2N@1386|Bacillus 91061|Bacilli E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system aroC GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01714 RC00586 ko00000,ko00001,ko00002,ko01000 - - - Chorismate_synt k141_15863_1 218284.CCDN010000002_gene2172 4.85e-147 422.0 COG4585@1|root,COG4585@2|Bacteria,1TPDG@1239|Firmicutes,4HC7E@91061|Bacilli,1ZB48@1386|Bacillus 91061|Bacilli T Histidine kinase vraS - 2.7.13.3 ko:K07681,ko:K11617 ko02020,map02020 M00480,M00481,M00754 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA_3 k141_6458_1 218284.CCDN010000008_gene4182 1.36e-147 426.0 COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,4HADT@91061|Bacilli,1ZAZA@1386|Bacillus 91061|Bacilli KT Transcriptional regulator - - - - - - - - - - - - HTH_8,PAS,PAS_9,Sigma54_activat k141_1571_1 1382305.AZUC01000016_gene2651 1.99e-14 70.1 COG0590@1|root,COG0590@2|Bacteria,1V3HZ@1239|Firmicutes,4HH7S@91061|Bacilli,26ESX@186818|Planococcaceae 91061|Bacilli FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) tadA GO:0002097,GO:0002100,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 3.5.4.33 ko:K11991 - - R10223 RC00477 ko00000,ko01000,ko03016 - - - MafB19-deam k141_1571_2 1123508.JH636447_gene7781 1.02e-24 100.0 COG1335@1|root,COG1335@2|Bacteria,2J0DR@203682|Planctomycetes 203682|Planctomycetes Q Isochorismatase family - - - - - - - - - - - - Isochorismatase k141_5219_2 1033734.CAET01000027_gene872 2.96e-180 520.0 COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HACS@91061|Bacilli,1ZATG@1386|Bacillus 91061|Bacilli IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - 6.2.1.3 ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding,AMP-binding_C k141_12481_1 1294265.JCM21738_3374 4.02e-196 552.0 COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli,1ZB5X@1386|Bacillus 91061|Bacilli G phosphotransferase system treP GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0015766,GO:0015771,GO:0015772,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563,GO:0090589 2.7.1.201 ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 M00270 R02780 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.13,4.A.1.2.4,4.A.1.2.8 - iYO844.BSU07800 PTS_EIIA_1,PTS_EIIB,PTS_EIIC k141_565_1 1122915.AUGY01000149_gene3100 1.73e-75 234.0 COG1957@1|root,COG1957@2|Bacteria,1TSSS@1239|Firmicutes,4HB17@91061|Bacilli,275F5@186822|Paenibacillaceae 91061|Bacilli F Hydrolyzes with equal efficiency cytidine or uridine to ribose and cytosine or uracil, respectively rihA - 3.2.2.1 ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 - R01245,R01273,R01677,R01770,R02143 RC00033,RC00063,RC00122,RC00318,RC00485 ko00000,ko00001,ko01000 - - - IU_nuc_hydro k141_10263_1 998674.ATTE01000001_gene4279 4.34e-41 145.0 COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,1RMYX@1236|Gammaproteobacteria,45ZSW@72273|Thiotrichales 72273|Thiotrichales J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis tuf - - ko:K02358 - - - - ko00000,ko03012,ko03029,ko04147 - - - GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 k141_1707_1 1249627.D779_1567 2.56e-33 132.0 COG1639@1|root,COG2199@1|root,COG1639@2|Bacteria,COG3706@2|Bacteria,1MVRF@1224|Proteobacteria,1RPH0@1236|Gammaproteobacteria,1WYQ7@135613|Chromatiales 135613|Chromatiales T HDOD domain - - - - - - - - - - - - GGDEF,HDOD k141_12682_1 1120973.AQXL01000118_gene473 5.33e-22 94.0 COG1051@1|root,COG1051@2|Bacteria,1V3T8@1239|Firmicutes,4HH2F@91061|Bacilli 91061|Bacilli F Belongs to the Nudix hydrolase family - - - - - - - - - - - - NIPSNAP,NUDIX k141_12682_2 1045004.OKIT_1404 5.9e-31 115.0 COG1434@1|root,COG1434@2|Bacteria,1V973@1239|Firmicutes,4HJHS@91061|Bacilli 91061|Bacilli S DUF218 domain - - - - - - - - - - - - DUF218 k141_23280_1 223926.28806639 8.84e-210 580.0 COG2513@1|root,COG2513@2|Bacteria,1N4VT@1224|Proteobacteria,1RMR5@1236|Gammaproteobacteria,1XUCR@135623|Vibrionales 135623|Vibrionales H Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate prpB GO:0003674,GO:0003824,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016829,GO:0016830,GO:0016833,GO:0044237,GO:0055114 4.1.3.30,5.4.2.9 ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 - R00409,R00661 RC00286,RC00287,RC02792 ko00000,ko00001,ko01000 - - - PEP_mutase k141_23280_2 675816.VIA_002925 1.31e-133 382.0 COG1802@1|root,COG1802@2|Bacteria,1NDRT@1224|Proteobacteria,1RYXQ@1236|Gammaproteobacteria,1XU1M@135623|Vibrionales 135623|Vibrionales K COG1802 Transcriptional regulators - - - - - - - - - - - - FCD,GntR k141_23280_3 675816.VIA_002902 0.0 902.0 COG2234@1|root,COG2234@2|Bacteria,1R77P@1224|Proteobacteria,1S0EQ@1236|Gammaproteobacteria,1XUIS@135623|Vibrionales 135623|Vibrionales S PA domain - - - - - - - - - - - - PA,Peptidase_M28 k141_23280_4 1219076.N646_0716 4.58e-220 608.0 COG3181@1|root,COG3181@2|Bacteria,1MXEX@1224|Proteobacteria,1RPKH@1236|Gammaproteobacteria,1XSIQ@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria VP1651 - - ko:K07795 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.80.1 - - TctC k141_23280_5 674977.VMC_33140 8.87e-105 303.0 2E729@1|root,331KW@2|Bacteria,1NEE1@1224|Proteobacteria,1SC21@1236|Gammaproteobacteria,1XV91@135623|Vibrionales 135623|Vibrionales S Tripartite tricarboxylate transporter TctB family - - - ko:K07794 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.80.1 - - TctB k141_23280_6 223926.28806644 0.0 908.0 COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,1RMQB@1236|Gammaproteobacteria,1XUNK@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria - - - ko:K07793 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.80.1 - - TctA k141_23280_7 674977.VMC_33100 9.46e-213 590.0 COG2358@1|root,COG2358@2|Bacteria,1MXW1@1224|Proteobacteria,1RQN1@1236|Gammaproteobacteria,1XU72@135623|Vibrionales 135623|Vibrionales S transport system periplasmic component - - - ko:K07080 - - - - ko00000 - - - NMT1_3 k141_23280_8 1116375.VEJY3_07895 0.0 1008.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,1XSW9@135623|Vibrionales 135623|Vibrionales C Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid - - - ko:K00138 ko00010,ko00620,ko01100,ko01110,ko01120,map00010,map00620,map01100,map01110,map01120 - R00711 RC00047 ko00000,ko00001,ko01000 - - - Aldedh k141_23280_9 1116375.VEJY3_07900 0.0 1006.0 COG3284@1|root,COG3284@2|Bacteria,1NRG5@1224|Proteobacteria,1RQMR@1236|Gammaproteobacteria,1XTDY@135623|Vibrionales 135623|Vibrionales K Transcriptional activator of acetoin glycerol metabolism - - - ko:K21405 - - - - ko00000,ko03000 - - - GAF,HTH_8,Sigma54_activat k141_23280_10 1116375.VEJY3_07905 3.27e-14 65.9 2AWW2@1|root,31NTF@2|Bacteria,1QKHG@1224|Proteobacteria,1TIMM@1236|Gammaproteobacteria,1XZCC@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_23280_12 223926.28806699 1.7e-55 180.0 2B2J9@1|root,31V4E@2|Bacteria,1QT0A@1224|Proteobacteria,1TI6D@1236|Gammaproteobacteria,1XYH3@135623|Vibrionales 135623|Vibrionales - - VP1707 - - - - - - - - - - - - k141_23280_13 298386.PBPRA0997 2.68e-73 229.0 28JEE@1|root,31WYY@2|Bacteria,1MYJR@1224|Proteobacteria,1TKJU@1236|Gammaproteobacteria,1Y0FY@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_23280_15 1280001.BAOA01000018_gene321 0.0 966.0 COG0362@1|root,COG0362@2|Bacteria,1MVV8@1224|Proteobacteria,1RM7P@1236|Gammaproteobacteria,1XTAI@135623|Vibrionales 135623|Vibrionales H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH gnd - 1.1.1.343,1.1.1.44 ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 M00004,M00006 R01528,R10221 RC00001,RC00539 ko00000,ko00001,ko00002,ko01000 - - - 6PGD,NAD_binding_2 k141_23280_16 1116375.VEJY3_07920 1.27e-161 453.0 COG0363@1|root,COG0363@2|Bacteria,1QXIZ@1224|Proteobacteria,1SB0N@1236|Gammaproteobacteria,1XT94@135623|Vibrionales 135623|Vibrionales G COG0363 6-phosphogluconolactonase Glucosamine-6-phosphate isomerase deaminase pgl - 3.1.1.31 ko:K01057 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R02035 RC00537 ko00000,ko00001,ko00002,ko01000 - - - Glucosamine_iso k141_23280_17 223926.28806702 0.0 884.0 COG0364@1|root,COG0364@2|Bacteria,1MUN0@1224|Proteobacteria,1RN76@1236|Gammaproteobacteria,1XSC7@135623|Vibrionales 135623|Vibrionales G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone zwf - 1.1.1.363,1.1.1.49 ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 M00004,M00006,M00008 R00835,R02736,R10907 RC00001,RC00066 ko00000,ko00001,ko00002,ko01000,ko04147 - - - G6PD_C,G6PD_N k141_24344_2 218284.CCDN010000001_gene735 3.92e-19 85.1 COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,4H9KA@91061|Bacilli,1ZC0R@1386|Bacillus 91061|Bacilli O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins dnaJ - - ko:K03686 - - - - ko00000,ko03029,ko03110 - - - DnaJ,DnaJ_C,DnaJ_CXXCXGXG k141_4208_1 1294265.JCM21738_2434 2.53e-73 228.0 COG2834@1|root,COG2834@2|Bacteria,1TSRE@1239|Firmicutes,4HBCH@91061|Bacilli,1ZBE6@1386|Bacillus 91061|Bacilli M COG2834 Outer membrane lipoprotein-sorting protein ydcC - - - - - - - - - - - DUF4367 k141_4208_2 1294265.JCM21738_2433 6.62e-29 105.0 COG0736@1|root,COG0736@2|Bacteria,1VA0T@1239|Firmicutes,4HKBI@91061|Bacilli,1ZI02@1386|Bacillus 91061|Bacilli I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein acpS - 2.7.8.7 ko:K00997 ko00770,map00770 - R01625 RC00002 ko00000,ko00001,ko01000 - - iYO844.BSU04620 ACPS k141_19672_1 649639.Bcell_3915 4.48e-16 79.3 28I0M@1|root,2Z85B@2|Bacteria,1TTBC@1239|Firmicutes,4HENN@91061|Bacilli,1ZCDZ@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3231) - - - - - - - - - - - - DUF3231 k141_1708_1 1295642.H839_15778 6.6e-21 91.3 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,4H9NS@91061|Bacilli,1WEUI@129337|Geobacillus 91061|Bacilli G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family gapA GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042866,GO:0043436,GO:0043891,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N k141_9001_6 1027273.GZ77_23185 8.47e-230 640.0 COG0582@1|root,COG0582@2|Bacteria,1N5SB@1224|Proteobacteria,1SAVC@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_integrase k141_9001_7 223926.28806139 4.25e-137 387.0 COG1435@1|root,COG1435@2|Bacteria,1NJR4@1224|Proteobacteria,1RPCK@1236|Gammaproteobacteria,1XT1V@135623|Vibrionales 135623|Vibrionales F Thymidine kinase tdk GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R01567,R02099,R08233 RC00002,RC00017 ko00000,ko00001,ko01000 - - - TK k141_22012_1 469610.HMPREF0189_01232 3.77e-26 112.0 COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,2VHYF@28216|Betaproteobacteria,1KJ9T@119065|unclassified Burkholderiales 28216|Betaproteobacteria O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE clpB - - ko:K03695 ko04213,map04213 - - - ko00000,ko00001,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N k141_27006_1 1453501.JELR01000005_gene1685 3.16e-130 385.0 COG4579@1|root,COG4579@2|Bacteria,1MVRB@1224|Proteobacteria,1RMC2@1236|Gammaproteobacteria,4655G@72275|Alteromonadaceae 1236|Gammaproteobacteria F Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation aceK GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004721,GO:0005488,GO:0005524,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008772,GO:0009987,GO:0016208,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0017076,GO:0018105,GO:0018193,GO:0018209,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050790,GO:0065007,GO:0065009,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.11.5 ko:K00906 - - - - ko00000,ko01000 - - - AceK k141_29102_1 218284.CCDN010000001_gene539 1.36e-162 471.0 COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,4HABZ@91061|Bacilli,1ZB5W@1386|Bacillus 91061|Bacilli J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) thrS GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD k141_23322_1 1347087.CBYO010000001_gene85 6.23e-67 211.0 COG0411@1|root,COG0411@2|Bacteria,1TR0P@1239|Firmicutes,4HASG@91061|Bacilli 91061|Bacilli E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component - - - ko:K01995 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C k141_31387_1 1294265.JCM21738_3388 6.84e-127 389.0 COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,4HAFP@91061|Bacilli,1ZBJ3@1386|Bacillus 91061|Bacilli V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran k141_6599_1 1279017.AQYJ01000026_gene51 2.09e-41 137.0 2E4VZ@1|root,32ZQ5@2|Bacteria,1N7XP@1224|Proteobacteria,1SCVI@1236|Gammaproteobacteria,468QB@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF3081) - - - - - - - - - - - - DUF3081 k141_13905_1 384765.SIAM614_02591 1.47e-07 53.5 COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,2TT5E@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q COG3653 N-acyl-D-aspartate D-glutamate deacylase - - - - - - - - - - - - Amidohydro_3 k141_20756_1 218284.CCDN010000005_gene3408 1.18e-107 313.0 2DBQ9@1|root,2ZACY@2|Bacteria,1V0WH@1239|Firmicutes,4HEH4@91061|Bacilli,1ZR7V@1386|Bacillus 91061|Bacilli S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) yutC - - - - - - - - - - - Spore_YhcN_YlaJ k141_16060_1 42565.FP66_07265 6.08e-116 337.0 COG1043@1|root,COG1043@2|Bacteria,1MUHQ@1224|Proteobacteria,1RPHB@1236|Gammaproteobacteria,1XHDF@135619|Oceanospirillales 135619|Oceanospirillales M Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxA - 2.3.1.129 ko:K00677 ko00540,ko01100,ko01503,map00540,map01100,map01503 M00060 R04567 RC00039,RC00055 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Acetyltransf_11,Hexapep k141_4230_1 1294265.JCM21738_1430 2.32e-137 393.0 COG1619@1|root,COG1619@2|Bacteria,1TRBB@1239|Firmicutes,4HAWT@91061|Bacilli,1ZC09@1386|Bacillus 91061|Bacilli V proteins, homologs of microcin C7 resistance protein MccF ykfA - 3.4.17.13 ko:K01297 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_S66 k141_19704_1 1279017.AQYJ01000027_gene1719 4.22e-161 484.0 COG0803@1|root,COG0803@2|Bacteria,1MY4H@1224|Proteobacteria,1S26I@1236|Gammaproteobacteria,46AMU@72275|Alteromonadaceae 1236|Gammaproteobacteria P Belongs to the bacterial solute-binding protein 9 family - - - - - - - - - - - - DUF4175 k141_27008_1 1121936.AUHI01000002_gene2621 2.58e-100 300.0 COG0451@1|root,COG0451@2|Bacteria,1VP6I@1239|Firmicutes,4HAN7@91061|Bacilli 91061|Bacilli M Nad-dependent epimerase dehydratase - - 5.1.3.6 ko:K08679 ko00520,ko01100,map00520,map01100 - R01385 RC00289 ko00000,ko00001,ko01000 - - - Epimerase,GDP_Man_Dehyd k141_27788_1 218284.CCDN010000002_gene2074 5.35e-43 148.0 COG1404@1|root,COG1404@2|Bacteria,1TPZ5@1239|Firmicutes,4HA5F@91061|Bacilli,1ZPUP@1386|Bacillus 91061|Bacilli O Belongs to the peptidase S8 family isp - - ko:K13275 - - - - ko00000,ko01000,ko01002,ko03110 - - - Peptidase_S8 k141_24378_2 223926.28808654 3.98e-238 657.0 COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,1RPB4@1236|Gammaproteobacteria,1XT9F@135623|Vibrionales 135623|Vibrionales V Transport permease protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 k141_18577_1 1123020.AUIE01000028_gene2555 1.04e-56 192.0 COG2272@1|root,COG2272@2|Bacteria,1MVQZ@1224|Proteobacteria,1RPFW@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Belongs to the type-B carboxylesterase lipase family - - - ko:K03929 - - - - ko00000,ko01000 - CE10 - COesterase k141_13906_1 218284.CCDN010000001_gene743 5.19e-146 423.0 COG1030@1|root,COG1030@2|Bacteria,1TR54@1239|Firmicutes,4H9P9@91061|Bacilli,1ZCTF@1386|Bacillus 91061|Bacilli O COG1030 Membrane-bound serine protease (ClpP class) yqeZ - - ko:K07403 - - - - ko00000 - - - NfeD,SDH_sah k141_23324_1 1294265.JCM21738_4189 1.77e-89 270.0 COG0491@1|root,COG0491@2|Bacteria,1TQPX@1239|Firmicutes,4HAV6@91061|Bacilli,1ZCFS@1386|Bacillus 91061|Bacilli S COG0491 Zn-dependent hydrolases, including glyoxylases yqjP - - - - - - - - - - - Lactamase_B k141_10282_1 218284.CCDN010000001_gene1895 1.35e-118 350.0 COG0750@1|root,COG0750@2|Bacteria,1TPMC@1239|Firmicutes,4HAQ5@91061|Bacilli,1ZCPQ@1386|Bacillus 91061|Bacilli M zinc metalloprotease rasP - - ko:K11749 ko02024,ko04112,map02024,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - PDZ_2,Peptidase_M50 k141_22013_1 983545.Glaag_2927 2.24e-33 139.0 COG1629@1|root,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria,4651V@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_7685_1 886379.AEWI01000130_gene1908 5.11e-48 160.0 2DMB9@1|root,32G5X@2|Bacteria,4NYAV@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - k141_29104_1 221109.22778369 1.65e-16 77.4 COG5146@1|root,COG5146@2|Bacteria,1V2R2@1239|Firmicutes,4HG04@91061|Bacilli,23K5X@182709|Oceanobacillus 91061|Bacilli F Fumble coaW - 2.7.1.33 ko:K09680 ko00770,ko01100,map00770,map01100 M00120 R02971,R03018,R04391 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Fumble k141_766_1 1196031.ALEG01000040_gene2912 2.75e-152 431.0 COG0084@1|root,COG0084@2|Bacteria,1TNY1@1239|Firmicutes,4HA74@91061|Bacilli,1ZB78@1386|Bacillus 91061|Bacilli L hydrolase, TatD tatD GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase k141_17236_1 28229.ND2E_2608 3.83e-25 107.0 COG0457@1|root,COG0457@2|Bacteria,1MVH9@1224|Proteobacteria,1RQ3R@1236|Gammaproteobacteria,2Q6HR@267889|Colwelliaceae 1236|Gammaproteobacteria S Tetratricopeptide repeats - - - - - - - - - - - - TPR_16,TPR_19,TPR_8 k141_32584_1 218284.CCDN010000001_gene1713 4.31e-89 266.0 2C009@1|root,32UHI@2|Bacteria,1V4P1@1239|Firmicutes,4HH50@91061|Bacilli,1ZE0W@1386|Bacillus 91061|Bacilli S FBP C-terminal treble-clef zinc-finger - - - - - - - - - - - - EF-G-binding_N,FBP_C k141_24379_1 555088.DealDRAFT_2227 1.77e-09 54.7 COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,24QJE@186801|Clostridia 186801|Clostridia K Cold shock protein - - - - - - - - - - - - CSD k141_24379_2 330214.NIDE2635 8.12e-07 54.7 COG2378@1|root,COG2378@2|Bacteria 2|Bacteria K regulation of single-species biofilm formation - - - ko:K13572 - - - - ko00000,ko03051 - - - HTH_11,WYL k141_13907_1 1121889.AUDM01000003_gene2395 7.03e-78 241.0 COG0451@1|root,COG0451@2|Bacteria,4NEZX@976|Bacteroidetes,1HWT7@117743|Flavobacteriia,2NSCX@237|Flavobacterium 976|Bacteroidetes GM dehydratase - - 4.1.1.35,5.1.3.2,5.1.3.7 ko:K01784,ko:K02473,ko:K08678 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R00418,R01384,R02984 RC00289,RC00508 ko00000,ko00001,ko00002,ko01000 - - - Epimerase,GDP_Man_Dehyd k141_13907_2 1280944.HY17_19080 3.43e-37 134.0 COG0451@1|root,COG0451@2|Bacteria,1MUGT@1224|Proteobacteria,2TRF6@28211|Alphaproteobacteria,43W4Z@69657|Hyphomonadaceae 28211|Alphaproteobacteria GM Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction fcl - 1.1.1.271 ko:K02377 ko00051,ko00520,ko01100,map00051,map00520,map01100 - R05692 RC01014 ko00000,ko00001,ko01000 - - - Epimerase k141_27009_1 42565.FP66_14310 4.31e-53 182.0 COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1MVJY@1224|Proteobacteria,1RRCA@1236|Gammaproteobacteria,1XI8F@135619|Oceanospirillales 135619|Oceanospirillales T Diguanylate cyclase - - - - - - - - - - - - CBS,EAL,GGDEF k141_27009_2 987059.RBXJA2T_13914 2.13e-38 147.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria 28216|Betaproteobacteria NT chemotaxis - - - ko:K03406,ko:K03776,ko:K05874,ko:K05875 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - 4HB_MCP_1,HAMP,MCPsignal,PAS_3,sCache_2 k141_25724_1 665952.HMPREF1015_02063 3.5e-125 379.0 COG0653@1|root,COG0653@2|Bacteria,1TSCF@1239|Firmicutes,4HBNY@91061|Bacilli,1ZD65@1386|Bacillus 91061|Bacilli U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA GO:0002790,GO:0003674,GO:0005215,GO:0006810,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0022804,GO:0022857,GO:0022884,GO:0032940,GO:0033036,GO:0042886,GO:0042887,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:1904680 - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - Helicase_C,SecA_DEAD,SecA_PP_bind,SecA_SW k141_20757_1 218284.CCDN010000001_gene1482 9.1e-230 640.0 COG2233@1|root,COG2233@2|Bacteria,1TNZZ@1239|Firmicutes,4HBAM@91061|Bacilli,1ZAUK@1386|Bacillus 91061|Bacilli F xanthine pbuX GO:0003674,GO:0005215,GO:0005345,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006863,GO:0008150,GO:0015205,GO:0015851,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0042906,GO:0042907,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072530,GO:1904823 - ko:K16169 - - - - ko00000,ko02000 2.A.40.3.1 - - Xan_ur_permease k141_31389_2 411473.RUMCAL_02995 3.46e-18 85.9 COG1477@1|root,COG1477@2|Bacteria,1TR9C@1239|Firmicutes,248KJ@186801|Clostridia,3WGXU@541000|Ruminococcaceae 186801|Clostridia H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein - - 2.7.1.180 ko:K03734 - - - - ko00000,ko01000 - - - ApbE k141_30193_2 1042377.AFPJ01000012_gene1400 3.36e-84 273.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,465DD@72275|Alteromonadaceae 1236|Gammaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k141_27791_1 388051.AUFE01000001_gene2115 6.95e-28 109.0 COG2386@1|root,COG2386@2|Bacteria,1NJB0@1224|Proteobacteria,2VNPU@28216|Betaproteobacteria,1K602@119060|Burkholderiaceae 28216|Betaproteobacteria U Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes ccmB - - ko:K02194 ko02010,map02010 M00259 - - ko00000,ko00001,ko00002,ko02000 3.A.1.107 - - CcmB k141_22014_1 1294265.JCM21738_3170 2.2e-105 304.0 COG1171@1|root,COG1171@2|Bacteria,1TP22@1239|Firmicutes,4H9NK@91061|Bacilli,1ZBM0@1386|Bacillus 91061|Bacilli E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA ilvA GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - - PALP,Thr_dehydrat_C k141_6604_1 218284.CCDN010000001_gene1080 4.48e-95 283.0 COG1408@1|root,COG1408@2|Bacteria,1V494@1239|Firmicutes,4HH1B@91061|Bacilli,1ZBFW@1386|Bacillus 91061|Bacilli S Calcineurin-like phosphoesterase superfamily domain ypbG - - ko:K07098 - - - - ko00000 - - - Metallophos,Metallophos_2 k141_18580_1 1453501.JELR01000002_gene825 1.98e-58 204.0 COG3866@1|root,COG3866@2|Bacteria,1QPFF@1224|Proteobacteria,1RQEM@1236|Gammaproteobacteria,465CX@72275|Alteromonadaceae 1236|Gammaproteobacteria G Amb_all pel1C - - - - - - - - - - - CBM_35,CBM_5_12_2,CBM_6,Pec_lyase_C,RicinB_lectin_2 k141_24380_1 580340.Tlie_0157 1.82e-45 162.0 COG1748@1|root,COG1748@2|Bacteria,3TBGS@508458|Synergistetes 508458|Synergistetes E COGs COG1748 Saccharopine dehydrogenase and related protein - - 1.4.1.18 ko:K19064 ko00960,ko01100,ko01110,map00960,map01100,map01110 - R00446,R02317 RC00062,RC00694 ko00000,ko00001,ko01000 - - - Sacchrp_dh_C,Sacchrp_dh_NADP k141_13908_1 1089551.KE386572_gene2699 7.22e-17 86.3 COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,2TR1D@28211|Alphaproteobacteria,4BQDW@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria E COG0747 ABC-type dipeptide transport system, periplasmic component dppA GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006457,GO:0006810,GO:0006857,GO:0008150,GO:0009987,GO:0015833,GO:0020037,GO:0030288,GO:0030313,GO:0031975,GO:0033218,GO:0042277,GO:0042597,GO:0042886,GO:0042938,GO:0044464,GO:0046906,GO:0048037,GO:0051179,GO:0051234,GO:0061077,GO:0071702,GO:0071705,GO:0097159,GO:1901363 - ko:K12368 ko02010,ko02030,map02010,map02030 M00324 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 k141_23327_1 1297742.A176_02902 2.43e-60 210.0 COG4206@1|root,COG4206@2|Bacteria,1QXUW@1224|Proteobacteria,43C7J@68525|delta/epsilon subdivisions,2X7HV@28221|Deltaproteobacteria,2YU5W@29|Myxococcales 28221|Deltaproteobacteria H CarboxypepD_reg-like domain - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec k141_14819_2 880071.Fleli_0540 6.06e-102 305.0 COG2159@1|root,COG2159@2|Bacteria,4NIGJ@976|Bacteroidetes,47KJH@768503|Cytophagia 976|Bacteroidetes S Amidohydrolase - - 4.1.1.45 ko:K03392 ko00380,ko01100,map00380,map01100 M00038 R04323 RC00779 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_2 k141_4232_1 1453501.JELR01000005_gene1784 1.57e-124 373.0 COG0642@1|root,COG2205@2|Bacteria,1MXF8@1224|Proteobacteria,1RMMI@1236|Gammaproteobacteria,465MX@72275|Alteromonadaceae 1236|Gammaproteobacteria T Signal transduction histidine kinase pilS - 2.7.13.3 ko:K02668 ko02020,map02020 M00501 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 - - - HATPase_c,HisKA,PAS_8 k141_6605_1 27337.EGY16554 4.77e-27 111.0 COG1052@1|root,KOG0069@2759|Eukaryota,38H7Z@33154|Opisthokonta,3P0JE@4751|Fungi,3QJY0@4890|Ascomycota,21662@147550|Sordariomycetes,1F1JC@1028384|Glomerellales 4751|Fungi C D-isomer specific 2-hydroxyacid dehydrogenase - - - - - - - - - - - - 2-Hacid_dh_C k141_18581_1 545693.BMQ_3710 3.56e-92 276.0 2DC2C@1|root,2ZCMC@2|Bacteria,1V2P6@1239|Firmicutes,4HG2Z@91061|Bacilli,1ZQQN@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF2935) - - - - - - - - - - - - DUF2935 k141_30194_1 218284.CCDN010000009_gene4320 8.96e-111 328.0 COG0477@1|root,COG2814@2|Bacteria,1TS3C@1239|Firmicutes,4HC3B@91061|Bacilli,1ZS79@1386|Bacillus 91061|Bacilli EGP Nucleoside H+ symporter ywbF - - ko:K05820 - - - - ko00000,ko02000 2.A.1.27 - - MFS_1_like k141_27792_1 1385513.N780_06535 3.89e-42 146.0 COG1514@1|root,COG1514@2|Bacteria,1VEU2@1239|Firmicutes,4HJD5@91061|Bacilli,2YAI9@289201|Pontibacillus 91061|Bacilli J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester - - - - - - - - - - - - LigT_PEase k141_27792_2 218284.CCDN010000008_gene4197 4.49e-10 59.3 28NSI@1|root,2ZB4U@2|Bacteria,1UZ00@1239|Firmicutes,4HDBT@91061|Bacilli,1ZDNP@1386|Bacillus 91061|Bacilli - - ytlQ - - - - - - - - - - - NERD k141_33936_2 1472418.BBJC01000005_gene2341 2.16e-17 89.4 COG0583@1|root,COG0583@2|Bacteria,1MXRP@1224|Proteobacteria,2TRVK@28211|Alphaproteobacteria 28211|Alphaproteobacteria K transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_33936_3 326297.Sama_2413 3.12e-126 385.0 COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria,2Q8YZ@267890|Shewanellaceae 1236|Gammaproteobacteria O PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - - - - - - - - - - PA,PKD,Peptidase_S8 k141_33936_5 1236541.BALL01000046_gene4107 4.57e-103 308.0 COG3221@1|root,COG3221@2|Bacteria,1MWFF@1224|Proteobacteria,1RSFI@1236|Gammaproteobacteria,2QAP1@267890|Shewanellaceae 1236|Gammaproteobacteria P TIGRFAM phosphonate ABC transporter, periplasmic phosphonate-binding protein - - - ko:K02044 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - Phosphonate-bd k141_33936_6 1236541.BALL01000046_gene4108 5.13e-99 298.0 COG3638@1|root,COG3638@2|Bacteria,1QXB1@1224|Proteobacteria,1T457@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system phnC - 3.6.3.28 ko:K02041 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.9 - - ABC_tran k141_33936_7 1236541.BALL01000046_gene4109 1.68e-127 369.0 COG3639@1|root,COG3639@2|Bacteria,1MW4F@1224|Proteobacteria,1SYKN@1236|Gammaproteobacteria 1236|Gammaproteobacteria P COG3639 ABC-type phosphate phosphonate transport system permease component - - - ko:K02042 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - BPD_transp_1 k141_12884_1 935837.JAEK01000003_gene4101 9.76e-21 84.0 COG4327@1|root,COG4327@2|Bacteria,1VDN3@1239|Firmicutes,4HM2W@91061|Bacilli,1ZHM0@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF4212) - - - - - - - - - - - - DUF4212 k141_12884_2 218284.CCDN010000007_gene4017 1.39e-62 206.0 COG4147@1|root,COG4147@2|Bacteria,1UHT5@1239|Firmicutes,4HCF6@91061|Bacilli,1ZCX7@1386|Bacillus 91061|Bacilli S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family ywcA - - ko:K14393 - - - - ko00000,ko02000 2.A.21.7 - - SSF k141_35399_1 218284.CCDN010000001_gene1341 3.68e-69 228.0 COG4548@1|root,COG4548@2|Bacteria,1TPW1@1239|Firmicutes,4HCPJ@91061|Bacilli,1ZD6R@1386|Bacillus 91061|Bacilli P Von Willebrand factor yojO - - - - - - - - - - - CobT_C,VWA k141_27321_1 349521.HCH_05643 1.35e-45 176.0 COG3209@1|root,COG3209@2|Bacteria,1QW4H@1224|Proteobacteria,1T42N@1236|Gammaproteobacteria,1XMP6@135619|Oceanospirillales 135619|Oceanospirillales M RHS Repeat - - - - - - - - - - - - RHS_repeat k141_34141_2 1279017.AQYJ01000019_gene1514 3.48e-104 319.0 COG5000@1|root,COG5000@2|Bacteria,1QVAT@1224|Proteobacteria,1T324@1236|Gammaproteobacteria,46D3E@72275|Alteromonadaceae 1236|Gammaproteobacteria T His Kinase A (phosphoacceptor) domain - - 2.7.13.3 ko:K02668 ko02020,map02020 M00501 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 - - - HATPase_c,HisKA k141_11677_1 1208323.B30_06051 7.8e-58 199.0 COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,2TQKP@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Belongs to the GPI family pgi GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGI k141_11677_2 1279017.AQYJ01000023_gene3289 6.67e-210 585.0 COG1609@1|root,COG1609@2|Bacteria,1MVUR@1224|Proteobacteria,1RN2K@1236|Gammaproteobacteria,4644S@72275|Alteromonadaceae 1236|Gammaproteobacteria K helix_turn _helix lactose operon repressor nagR - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 k141_4361_2 911239.CF149_08212 3.64e-05 46.6 COG3048@1|root,COG3048@2|Bacteria,1MUJS@1224|Proteobacteria,1RNBW@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Belongs to the serine threonine dehydratase family. DsdA subfamily dsdA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0008721,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009636,GO:0009987,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016840,GO:0016841,GO:0017144,GO:0019478,GO:0019752,GO:0019842,GO:0030170,GO:0033554,GO:0036088,GO:0036094,GO:0042221,GO:0042737,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046416,GO:0048037,GO:0050662,GO:0050896,GO:0051410,GO:0051716,GO:0070178,GO:0070279,GO:0071704,GO:0097159,GO:0098754,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901698 4.3.1.18 ko:K01753 ko00260,map00260 - R00221 RC02600 ko00000,ko00001,ko01000 - - iECED1_1282.ECED1_2813,iLF82_1304.LF82_0525,iNRG857_1313.NRG857_11890 PALP k141_29318_1 1198114.AciX9_0467 2.1e-50 172.0 COG4965@1|root,COG4965@2|Bacteria,3Y4RR@57723|Acidobacteria,2JJ91@204432|Acidobacteriia 204432|Acidobacteriia U Type II secretion system - - - ko:K12510 - - - - ko00000,ko02044 - - - T2SSF k141_18911_1 243231.GSU0493 1.44e-63 211.0 COG1252@1|root,COG1252@2|Bacteria,1MX96@1224|Proteobacteria,42PFG@68525|delta/epsilon subdivisions,2WKPM@28221|Deltaproteobacteria,43TYK@69541|Desulfuromonadales 28221|Deltaproteobacteria C PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase ndh2 - 1.6.99.3 ko:K03885 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - Pyr_redox_2 k141_14218_1 981383.AEWH01000064_gene1851 8.56e-35 122.0 COG2816@1|root,COG2816@2|Bacteria,1V5G3@1239|Firmicutes,4HH9P@91061|Bacilli 91061|Bacilli L DNA mismatch repair protein MutT - - - - - - - - - - - - NUDIX k141_14218_2 1033734.CAET01000030_gene4003 3.34e-52 171.0 COG1028@1|root,COG1028@2|Bacteria,1TSCT@1239|Firmicutes,4HD4Z@91061|Bacilli,1ZD54@1386|Bacillus 91061|Bacilli IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) gdh - - - - - - - - - - - adh_short_C2 k141_3147_1 1132442.KB889753_gene82 3.25e-75 236.0 COG0475@1|root,COG0475@2|Bacteria,1TS32@1239|Firmicutes,4HAGC@91061|Bacilli,1ZQCE@1386|Bacillus 91061|Bacilli P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family napA GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008324,GO:0009847,GO:0015075,GO:0015077,GO:0015081,GO:0015291,GO:0015297,GO:0015318,GO:0015672,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0032502,GO:0034220,GO:0035725,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0098655,GO:0098660,GO:0098662 - - - - - - - - - - Na_H_Exchanger k141_22298_1 218284.CCDN010000001_gene969 2.31e-140 403.0 COG0142@1|root,COG0142@2|Bacteria,1TPQY@1239|Firmicutes,4HA8E@91061|Bacilli,1ZC4G@1386|Bacillus 91061|Bacilli H Belongs to the FPP GGPP synthase family ispA GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0071704,GO:1901576 2.5.1.1,2.5.1.10,2.5.1.29 ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00366 R01658,R02003,R02061 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 - - - polyprenyl_synt k141_11678_1 1042377.AFPJ01000024_gene779 3.25e-67 213.0 COG3660@1|root,COG3660@2|Bacteria,1RC47@1224|Proteobacteria,1S53F@1236|Gammaproteobacteria,469PG@72275|Alteromonadaceae 1236|Gammaproteobacteria M Mitochondrial fission ELM1 - - - ko:K07276 - - - - ko00000 - - - Mito_fiss_Elm1 k141_27957_2 1453501.JELR01000005_gene1566 1.72e-313 874.0 COG4773@1|root,COG4773@2|Bacteria,1QTXJ@1224|Proteobacteria,1T2BS@1236|Gammaproteobacteria,46D8F@72275|Alteromonadaceae 1236|Gammaproteobacteria P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec k141_12885_1 218284.CCDN010000001_gene328 6.45e-46 162.0 COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,4HADT@91061|Bacilli,1ZAZA@1386|Bacillus 91061|Bacilli KT Transcriptional regulator - - - - - - - - - - - - HTH_8,PAS,PAS_10,PAS_9,Sigma54_activat k141_12885_2 218284.CCDN010000001_gene329 8.73e-22 93.2 COG0006@1|root,COG0006@2|Bacteria,1TQ6R@1239|Firmicutes,4HA5I@91061|Bacilli,1ZBZE@1386|Bacillus 91061|Bacilli E COG0006 Xaa-Pro aminopeptidase - - - - - - - - - - - - Creatinase_N,Peptidase_M24 k141_18912_1 218284.CCDN010000002_gene2236 1.04e-110 324.0 COG1295@1|root,COG1295@2|Bacteria,1U7HM@1239|Firmicutes,4H9MJ@91061|Bacilli,1ZCAD@1386|Bacillus 91061|Bacilli S Belongs to the UPF0761 family yihY - - ko:K07058 - - - - ko00000 - - - Virul_fac_BrkB k141_4362_1 1380390.JIAT01000015_gene5815 1.15e-09 58.5 COG5483@1|root,COG5483@2|Bacteria,2IHSH@201174|Actinobacteria,4CS9A@84995|Rubrobacteria 84995|Rubrobacteria S Protein of unknown function, DUF488 - - - - - - - - - - - - DUF488 k141_954_1 218284.CCDN010000001_gene206 4.09e-87 269.0 COG1721@1|root,COG1721@2|Bacteria,1U0JI@1239|Firmicutes,4HDNW@91061|Bacilli,1ZDIV@1386|Bacillus 91061|Bacilli S Protein of unknown function DUF58 - - - - - - - - - - - - DUF58 k141_37538_1 1121937.AUHJ01000012_gene2788 4.39e-224 645.0 COG4772@1|root,COG4772@2|Bacteria,1NTC4@1224|Proteobacteria,1RPFQ@1236|Gammaproteobacteria,464RR@72275|Alteromonadaceae 1236|Gammaproteobacteria P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec k141_14219_1 218284.CCDN010000007_gene3861 1.01e-112 352.0 COG1511@1|root,COG1511@2|Bacteria,1UZD1@1239|Firmicutes,4HEK8@91061|Bacilli,1ZC64@1386|Bacillus 91061|Bacilli S domain protein yueB - - - - - - - - - - - ABC2_membrane_3 k141_11679_1 218284.CCDN010000001_gene806 8.6e-76 244.0 COG1368@1|root,COG1368@2|Bacteria,1TRMA@1239|Firmicutes,4H9S0@91061|Bacilli,1ZBBV@1386|Bacillus 91061|Bacilli M Belongs to the LTA synthase family yqgS - 2.7.8.20 ko:K01138,ko:K19005 ko00561,ko01100,map00561,map01100 - R05081,R10849 RC00017 ko00000,ko00001,ko01000 - - - Sulfatase k141_35401_1 218284.CCDN010000008_gene4145 6.56e-178 496.0 COG0447@1|root,COG0447@2|Bacteria,1UHNU@1239|Firmicutes,4HAD0@91061|Bacilli,1ZB3B@1386|Bacillus 91061|Bacilli H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) menB GO:0003674,GO:0003824,GO:0005488,GO:0006732,GO:0008150,GO:0008152,GO:0008935,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0042180,GO:0042181,GO:0043167,GO:0043168,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:0071890,GO:1901576,GO:1901661,GO:1901663 4.1.3.36 ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R07263 RC01923 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 k141_20931_1 1415754.JQMK01000013_gene104 7.32e-65 212.0 COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,1MUDN@1224|Proteobacteria,1RMMG@1236|Gammaproteobacteria,465X6@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0491 Zn-dependent hydrolases, including glyoxylases - - 3.1.2.6 ko:K01069 ko00620,map00620 - R01736 RC00004,RC00137 ko00000,ko00001,ko01000 - - - Lactamase_B,Rhodanese k141_955_1 218284.CCDN010000002_gene2009 3e-121 375.0 COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,4HABE@91061|Bacilli,1ZPZA@1386|Bacillus 91061|Bacilli EF Carbamoyl-phosphate synthetase ammonia chain carB GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS k141_27958_1 218284.CCDN010000001_gene1593 4.84e-122 354.0 COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,4HA2S@91061|Bacilli,1ZAUS@1386|Bacillus 91061|Bacilli P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components dppB GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0022857,GO:0051179,GO:0051234,GO:0055085 - ko:K16200 ko02010,map02010 M00566 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.2 - iYO844.BSU12930 BPD_transp_1 k141_3148_1 1033734.CAET01000069_gene2361 1.83e-39 137.0 COG2131@1|root,COG2131@2|Bacteria,1V3PU@1239|Firmicutes,4HCDG@91061|Bacilli,1ZBGM@1386|Bacillus 91061|Bacilli F COG2131 Deoxycytidylate deaminase comEB - 3.5.4.12 ko:K01493 ko00240,ko01100,map00240,map01100 M00429 R01663 RC00074 ko00000,ko00001,ko00002,ko01000,ko02044 - - - dCMP_cyt_deam_1 k141_19913_1 1001585.MDS_0762 4.91e-287 789.0 COG0174@1|root,COG0174@2|Bacteria,1MU6V@1224|Proteobacteria,1RPNZ@1236|Gammaproteobacteria,1YI0P@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria E Belongs to the glutamine synthetase family - - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C k141_19913_2 399739.Pmen_0677 2.06e-220 619.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,1YF1V@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria C belongs to the aldehyde dehydrogenase family - - - - - - - - - - - - Aldedh k141_25943_1 1279017.AQYJ01000024_gene1004 3.08e-154 441.0 COG0697@1|root,COG0697@2|Bacteria,1PGSE@1224|Proteobacteria,1RMZY@1236|Gammaproteobacteria,4673D@72275|Alteromonadaceae 1236|Gammaproteobacteria EG EamA-like transporter family yhbE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - EamA k141_36333_1 42565.FP66_12535 3.65e-104 303.0 COG0512@1|root,COG0512@2|Bacteria,1MV5Y@1224|Proteobacteria,1RMQW@1236|Gammaproteobacteria,1XH6R@135619|Oceanospirillales 135619|Oceanospirillales EH with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine trpG - 4.1.3.27 ko:K01658 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - GATase k141_36333_2 42565.FP66_12530 1.54e-57 187.0 COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,1RNXV@1236|Gammaproteobacteria,1XIT8@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) trpD - 2.4.2.18 ko:K00766 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R01073 RC00440 ko00000,ko00001,ko00002,ko01000 - - - Glycos_trans_3N,Glycos_transf_3 k141_32830_3 1453501.JELR01000001_gene2382 9.17e-23 93.2 COG2165@1|root,COG2165@2|Bacteria 2|Bacteria NU general secretion pathway protein gspH - - ko:K02457,ko:K02650 ko02020,ko03070,ko05111,map02020,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 - - GspH,N_methyl k141_981_1 218284.CCDN010000001_gene953 3.76e-145 414.0 COG3854@1|root,COG3854@2|Bacteria,1TQ23@1239|Firmicutes,4HA2K@91061|Bacilli,1ZAWB@1386|Bacillus 91061|Bacilli S stage III sporulation protein AA spoIIIAA - - ko:K06390 - - - - ko00000 - - - AAA,T2SSE k141_11697_1 203122.Sde_0789 1.18e-128 372.0 COG3507@1|root,COG3507@2|Bacteria,1QBSN@1224|Proteobacteria,1RNBA@1236|Gammaproteobacteria,464BQ@72275|Alteromonadaceae 1236|Gammaproteobacteria G Glycosyl hydrolases family 43 - - - - - - - - - - - - AbfB,Glyco_hydro_43 k141_25973_1 218284.CCDN010000001_gene132 7.54e-114 357.0 COG1038@1|root,COG1038@2|Bacteria,1UHP9@1239|Firmicutes,4IS56@91061|Bacilli,1ZC4R@1386|Bacillus 91061|Bacilli C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second pyc - 6.4.1.1 ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 M00173 R00344 RC00040,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,HMGL-like,PYC_OADA k141_22324_1 1415778.JQMM01000001_gene2181 4.22e-73 235.0 COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,1RP4V@1236|Gammaproteobacteria,1J5DU@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit atpA1 - 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N k141_24645_1 909613.UO65_3777 5.55e-25 105.0 COG2114@1|root,COG2114@2|Bacteria,2I900@201174|Actinobacteria,4E4WE@85010|Pseudonocardiales 201174|Actinobacteria T Adenylyl- / guanylyl cyclase, catalytic domain - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv1647 Guanylate_cyc k141_14246_1 1196031.ALEG01000072_gene925 5.39e-112 336.0 COG0069@1|root,COG0069@2|Bacteria,1TSHA@1239|Firmicutes,4HA97@91061|Bacilli,1ZCQH@1386|Bacillus 91061|Bacilli E Belongs to the glutamate synthase family yerD GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.7.1 ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 - R00021,R10086 RC00006,RC00010 ko00000,ko00001,ko01000 - - - Glu_synthase k141_17395_1 218284.CCDN010000004_gene3081 2.68e-120 347.0 COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,4HARE@91061|Bacilli,1ZC55@1386|Bacillus 91061|Bacilli S reductase yvgN - - - - - - - - - - - Aldo_ket_red k141_3164_1 218284.CCDN010000007_gene3824 1.11e-32 125.0 COG0739@1|root,COG0739@2|Bacteria,1TRWJ@1239|Firmicutes,4HB43@91061|Bacilli,1ZBXH@1386|Bacillus 91061|Bacilli M G5 nlpD - - - - - - - - - - - G5,LysM,Peptidase_M23 k141_7933_1 1279017.AQYJ01000022_gene2750 7.63e-72 223.0 COG0584@1|root,COG0584@2|Bacteria 2|Bacteria C glycerophosphodiester phosphodiesterase activity - - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - GDPD k141_7933_2 1279017.AQYJ01000022_gene2749 9.28e-211 591.0 COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,1RMGP@1236|Gammaproteobacteria,46472@72275|Alteromonadaceae 1236|Gammaproteobacteria C FAD dependent oxidoreductase eryB - 1.1.5.3 ko:K00111 ko00564,ko01110,map00564,map01110 - R00848 RC00029 ko00000,ko00001,ko01000 - - - DAO,DAO_C k141_7933_3 1453501.JELR01000002_gene300 4.97e-198 554.0 COG0042@1|root,COG0042@2|Bacteria,1MUY1@1224|Proteobacteria,1RN28@1236|Gammaproteobacteria,464FI@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs dusA GO:0002943,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016491,GO:0016627,GO:0017150,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055114,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 - ko:K05539 - - - - ko00000,ko01000,ko03016 - - - Dus k141_7933_5 1042377.AFPJ01000052_gene1561 2.34e-63 198.0 COG4103@1|root,COG4103@2|Bacteria,1N6YZ@1224|Proteobacteria,1SD1K@1236|Gammaproteobacteria,468DI@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - TerB k141_7933_7 1453501.JELR01000002_gene304 2.9e-195 552.0 COG2204@1|root,COG2208@1|root,COG2204@2|Bacteria,COG2208@2|Bacteria,1QU7V@1224|Proteobacteria,1T1QA@1236|Gammaproteobacteria,46693@72275|Alteromonadaceae 1236|Gammaproteobacteria KT COG0784 FOG CheY-like receiver - - 3.1.3.3 ko:K07315 - - - - ko00000,ko01000,ko03021 - - - Response_reg,SpoIIE k141_7933_8 1279017.AQYJ01000022_gene2741 8.06e-108 323.0 COG2853@1|root,COG2853@2|Bacteria,1MVX0@1224|Proteobacteria,1RNPS@1236|Gammaproteobacteria,466E2@72275|Alteromonadaceae 1236|Gammaproteobacteria M Surface lipoprotein vacJ - - ko:K04754 - - - - ko00000 - - - MlaA k141_7933_9 1279017.AQYJ01000022_gene2740 3.34e-121 353.0 COG3219@1|root,COG3219@2|Bacteria,1R8C9@1224|Proteobacteria,1S23S@1236|Gammaproteobacteria,4673F@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria - - - ko:K09929 - - - - ko00000 - - - DUF2063 k141_7933_10 1279017.AQYJ01000022_gene2739 8.19e-163 460.0 COG3220@1|root,COG3220@2|Bacteria,1MURE@1224|Proteobacteria,1RQ9H@1236|Gammaproteobacteria,464IP@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria - - - ko:K09930 - - - - ko00000 - - - DUF692 k141_7933_11 1042377.AFPJ01000052_gene1567 3.53e-13 67.4 COG3767@1|root,COG3767@2|Bacteria 2|Bacteria - - - - 3.2.1.4 ko:K01179 ko00500,ko01100,map00500,map01100 - R06200,R11307,R11308 - ko00000,ko00001,ko01000 - GH5,GH9 - EF-hand_5 k141_7933_12 1279017.AQYJ01000022_gene2737 0.0 2098.0 COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,1RMU1@1236|Gammaproteobacteria,464K7@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG1643 HrpA-like helicases hrpA GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0006139,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 3.6.4.13 ko:K03578 - - - - ko00000,ko01000 - - - DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind k141_7933_13 1279017.AQYJ01000022_gene2736 2.3e-314 861.0 COG3104@1|root,COG3104@2|Bacteria,1MW6W@1224|Proteobacteria,1RM8P@1236|Gammaproteobacteria,4643X@72275|Alteromonadaceae 1236|Gammaproteobacteria E POT family - - - ko:K03305 - - - - ko00000 2.A.17 - - PTR2 k141_7933_18 351348.Maqu_1608 1.53e-63 198.0 COG2983@1|root,COG2983@2|Bacteria,1RHMX@1224|Proteobacteria,1S5XU@1236|Gammaproteobacteria,46785@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the UPF0260 family ycgN - - ko:K09160 - - - - ko00000 - - - CxxCxxCC k141_7933_19 390235.PputW619_3899 1.82e-26 100.0 COG3100@1|root,COG3100@2|Bacteria,1N83J@1224|Proteobacteria,1SCCD@1236|Gammaproteobacteria,1YVIE@136845|Pseudomonas putida group 1236|Gammaproteobacteria S YcgL domain-containing protein ycgL - - ko:K09902 - - - - ko00000 - - - YcgL k141_7933_20 1279017.AQYJ01000022_gene2729 1.01e-199 561.0 COG0349@1|root,COG0349@2|Bacteria,1MURV@1224|Proteobacteria,1RPBP@1236|Gammaproteobacteria,464UE@72275|Alteromonadaceae 1236|Gammaproteobacteria J Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides rnd GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0033890,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360 3.1.13.5 ko:K03684 - - - - ko00000,ko01000,ko03016 - - - DNA_pol_A_exo1,HRDC k141_7933_21 1279017.AQYJ01000022_gene2728 4.08e-120 345.0 COG0353@1|root,COG0353@2|Bacteria,1MV9Q@1224|Proteobacteria,1RN99@1236|Gammaproteobacteria,466DN@72275|Alteromonadaceae 1236|Gammaproteobacteria L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO recR GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - ko:K06187 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecR,Toprim_4 k141_7933_23 1279017.AQYJ01000022_gene2726 9.22e-277 786.0 COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,1RMIA@1236|Gammaproteobacteria,464IG@72275|Alteromonadaceae 1236|Gammaproteobacteria L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity dnaX GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030234,GO:0030337,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0042802,GO:0043170,GO:0043846,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050790,GO:0061695,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0098772,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNA_pol3_gamma3,DNA_pol3_tau_4,DNA_pol3_tau_5 k141_7933_25 1042377.AFPJ01000052_gene1581 4.82e-162 463.0 COG3712@1|root,COG3712@2|Bacteria,1MZCK@1224|Proteobacteria,1S88I@1236|Gammaproteobacteria,467V5@72275|Alteromonadaceae 1236|Gammaproteobacteria PT Domain of unknown function (DUF4880) - - - ko:K07165 - - - - ko00000 - - - DUF4880,DUF4974,FecR k141_7933_26 1042377.AFPJ01000052_gene1582 1.34e-73 247.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria,4651V@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec k141_6914_2 1453501.JELR01000002_gene933 4.59e-215 600.0 COG1600@1|root,COG1600@2|Bacteria,1MV1H@1224|Proteobacteria,1RMD9@1236|Gammaproteobacteria,46459@72275|Alteromonadaceae 1236|Gammaproteobacteria C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) queG GO:0003674,GO:0003824,GO:0006091,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009055,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0022900,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 ko:K18979 - - - - ko00000,ko01000,ko03016 - - - DUF1730,Fer4_16 k141_6914_3 1279017.AQYJ01000027_gene1572 2.24e-127 377.0 COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,1RMPS@1236|Gammaproteobacteria,4654W@72275|Alteromonadaceae 1236|Gammaproteobacteria G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration nnrD GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 - - - - ko00000,ko01000 - - - Carb_kinase,YjeF_N k141_24646_1 218284.CCDN010000005_gene3198 3.07e-39 137.0 28PM4@1|root,2ZCA8@2|Bacteria,1V1PA@1239|Firmicutes,4HFNN@91061|Bacilli,1ZG8T@1386|Bacillus 91061|Bacilli S YtkA-like ytkA - - - - - - - - - - - PKD,YtkA k141_14248_1 1453501.JELR01000002_gene690 1.02e-83 265.0 COG0471@1|root,COG0569@1|root,COG0471@2|Bacteria,COG0569@2|Bacteria,1MU0K@1224|Proteobacteria,1RMI1@1236|Gammaproteobacteria,464A6@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0471 Di- and tricarboxylate transporters - - - - - - - - - - - - CitMHS,TrkA_C k141_35428_1 1283300.ATXB01000001_gene1702 6.53e-139 416.0 COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,1RPAV@1236|Gammaproteobacteria,1XDT1@135618|Methylococcales 135618|Methylococcales L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA ligA - 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - - BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5 k141_35428_2 1283300.ATXB01000001_gene1705 1.17e-89 282.0 COG1387@1|root,COG1387@2|Bacteria,1MYXV@1224|Proteobacteria,1SZW9@1236|Gammaproteobacteria,1XFPE@135618|Methylococcales 135618|Methylococcales L DNA polymerase X family - - - ko:K02347 - - - - ko00000,ko03400 - - - DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8,PHP k141_6915_2 1169144.KB910984_gene3842 2.1e-55 182.0 COG4977@1|root,COG4977@2|Bacteria,1V34W@1239|Firmicutes,4HGHX@91061|Bacilli,1ZEN3@1386|Bacillus 91061|Bacilli K helix_turn_helix, arabinose operon control protein - - - - - - - - - - - - HTH_18 k141_9333_2 1395513.P343_12780 1.44e-30 119.0 COG1484@1|root,COG1484@2|Bacteria,1V5FC@1239|Firmicutes,4HI1I@91061|Bacilli 91061|Bacilli L IstB-like ATP binding protein - - - ko:K02315 - - - - ko00000,ko03032 - - - IstB_IS21 k141_18953_1 1238450.VIBNISOn1_370007 1.16e-205 582.0 COG1178@1|root,COG1178@2|Bacteria,1MXZZ@1224|Proteobacteria,1RY3W@1236|Gammaproteobacteria,1XTGS@135623|Vibrionales 135623|Vibrionales P ABC-type Fe3 transport system, permease component - - - ko:K02011 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - BPD_transp_1 k141_18953_2 1238450.VIBNISOn1_370006 4.19e-204 571.0 COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,1RMTS@1236|Gammaproteobacteria,1XSM6@135623|Vibrionales 135623|Vibrionales P Belongs to the ABC transporter superfamily - - 3.6.3.30 ko:K02010,ko:K02052 ko02010,ko02024,map02010,map02024 M00190,M00193 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.10,3.A.1.11 - - ABC_tran,TOBE_2 k141_22327_1 218284.CCDN010000001_gene616 4.75e-90 275.0 COG1459@1|root,COG1459@2|Bacteria,1TQRZ@1239|Firmicutes,4HBFI@91061|Bacilli,1ZD1H@1386|Bacillus 91061|Bacilli NU type II secretion system pilC - - ko:K02653 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSF k141_7934_1 1140002.I570_02924 0.000201 43.5 COG4926@1|root,COG4926@2|Bacteria,1TQHW@1239|Firmicutes,4HFA8@91061|Bacilli,4B25H@81852|Enterococcaceae 91061|Bacilli S Prophage endopeptidase tail - - - - - - - - - - - - Prophage_tail k141_32861_1 521098.Aaci_2480 2.47e-45 158.0 COG0476@1|root,COG0476@2|Bacteria,1TQ3U@1239|Firmicutes,4HBGP@91061|Bacilli,277WP@186823|Alicyclobacillaceae 91061|Bacilli H ThiF family moeB - 2.7.7.73,2.7.7.80 ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07459 RC00043 ko00000,ko00001,ko01000 - - - ThiF k141_19928_1 1116375.VEJY3_02460 6.54e-221 613.0 COG2377@1|root,COG2377@2|Bacteria,1MV4E@1224|Proteobacteria,1RNTZ@1236|Gammaproteobacteria,1XTEE@135623|Vibrionales 135623|Vibrionales F Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling anmK - 2.7.1.170 ko:K09001 - - - - ko00000,ko01000 - - - AnmK k141_19928_2 1116375.VEJY3_02455 1.41e-195 545.0 COG2103@1|root,COG2103@2|Bacteria,1MVDR@1224|Proteobacteria,1RN3P@1236|Gammaproteobacteria,1XUH3@135623|Vibrionales 135623|Vibrionales S Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling murQ - 4.2.1.126 ko:K07106 ko00520,ko01100,map00520,map01100 - R08555 RC00397,RC00746 ko00000,ko00001,ko01000 - - - SIS,SIS_2 k141_19928_4 1116375.VEJY3_02445 4.08e-72 217.0 2ED5M@1|root,3372C@2|Bacteria,1N2Z7@1224|Proteobacteria,1SEVD@1236|Gammaproteobacteria,1XY03@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF2799) - - - - - - - - - - - - DUF2799 k141_19928_5 1116375.VEJY3_02440 0.0 918.0 COG1966@1|root,COG1966@2|Bacteria,1MWF9@1224|Proteobacteria,1RMG4@1236|Gammaproteobacteria,1XSKR@135623|Vibrionales 135623|Vibrionales T Carbon starvation protein cstA - - - - - - - - - - - CstA,CstA_5TM k141_5715_1 1116375.VEJY3_19921 2.83e-256 718.0 COG2200@1|root,COG2203@1|root,COG2200@2|Bacteria,COG2203@2|Bacteria,1RGKE@1224|Proteobacteria,1T1I8@1236|Gammaproteobacteria,1XUWZ@135623|Vibrionales 135623|Vibrionales T GGDEF family - - 3.1.4.52 ko:K20962 ko05111,map05111 - - - ko00000,ko00001,ko01000 - - - EAL,GAF,GAF_2,GGDEF k141_7955_26 268747.Q58LJ7_BPPRS 9.6e-179 523.0 4QHDM@10239|Viruses,4QYV6@35237|dsDNA viruses no RNA stage,4QRD0@28883|Caudovirales,4QI2W@10662|Myoviridae 10662|Myoviridae S Terminase-like family - GO:0003674,GO:0003824,GO:0004518,GO:0005575,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016032,GO:0016043,GO:0016787,GO:0016788,GO:0019058,GO:0019068,GO:0019069,GO:0019072,GO:0019075,GO:0022607,GO:0032991,GO:0034641,GO:0043170,GO:0043493,GO:0044085,GO:0044237,GO:0044238,GO:0044403,GO:0044419,GO:0046483,GO:0046797,GO:0051704,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0098009,GO:1901360,GO:1902494,GO:1904949 - - - - - - - - - - - k141_7955_27 1357423.S5MCV4_9CAUD 2.17e-78 265.0 4QAZ6@10239|Viruses,4QUU8@35237|dsDNA viruses no RNA stage,4QPHV@28883|Caudovirales,4QI4H@10662|Myoviridae 10662|Myoviridae S Phage tail sheath protein - GO:0005575,GO:0019012,GO:0044423,GO:0098015,GO:0098027 - - - - - - - - - - - k141_7955_28 1079999.H8ZNA5_9CAUD 5.36e-38 136.0 4QAQQ@10239|Viruses,4QVZX@35237|dsDNA viruses no RNA stage,4QPBX@28883|Caudovirales,4QIBM@10662|Myoviridae 10662|Myoviridae S T4-like virus tail tube protein gp19 - - - - - - - - - - - - - k141_7955_29 445683.E3SK21_9CAUD 2.11e-143 432.0 4QBAK@10239|Viruses,4QY34@35237|dsDNA viruses no RNA stage,4QQBQ@28883|Caudovirales,4QIQI@10662|Myoviridae 10662|Myoviridae S Bacteriophage T4-like capsid assembly protein (Gp20) - GO:0005575,GO:0019012 - - - - - - - - - - - k141_7955_32 445686.E3SL64_9CAUD 7.44e-42 149.0 4QAWI@10239|Viruses,4QW40@35237|dsDNA viruses no RNA stage,4QPUX@28883|Caudovirales,4QINW@10662|Myoviridae 10662|Myoviridae S Pfam:Peptidase_S77 - - - - - - - - - - - - - k141_7955_33 1357423.S5MAQ6_9CAUD 5.54e-30 120.0 4QFVD@10239|Viruses,4QWU0@35237|dsDNA viruses no RNA stage,4QTCC@28883|Caudovirales,4QICC@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k141_7955_34 445686.E3SL66_9CAUD 2.12e-131 393.0 4QAJ5@10239|Viruses,4QUS9@35237|dsDNA viruses no RNA stage,4QPY5@28883|Caudovirales,4QHUT@10662|Myoviridae 10662|Myoviridae S Major capsid protein Gp23 - GO:0005575,GO:0019012,GO:0019028,GO:0044423 - - - - - - - - - - - k141_7955_35 268746.Q58ML6_BPPRM 1.8e-19 85.9 4QE8Y@10239|Viruses,4QW3S@35237|dsDNA viruses no RNA stage,4QPGZ@28883|Caudovirales,4QISX@10662|Myoviridae 10662|Myoviridae S Recombination, repair and ssDNA binding protein UvsY - - - - - - - - - - - - - k141_7955_36 1204516.I6XM03_9CAUD 1.31e-05 50.8 4QAQQ@10239|Viruses,4QVZX@35237|dsDNA viruses no RNA stage,4QPBX@28883|Caudovirales,4QIBM@10662|Myoviridae 10662|Myoviridae S T4-like virus tail tube protein gp19 - - - - - - - - - - - - - k141_7955_41 263358.VAB18032_16175 9.96e-05 50.4 2CDGZ@1|root,34CGM@2|Bacteria,2GYBU@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k141_7955_44 1540095.A0A0A0YTN8_9CAUD 6.92e-100 317.0 4QB5I@10239|Viruses,4QPQ9@28883|Caudovirales,4QI9F@10662|Myoviridae 10662|Myoviridae S Type III restriction enzyme, res subunit - - - - - - - - - - - - - k141_7955_46 283699.D172_0377 7.09e-62 218.0 2DBV3@1|root,2ZB9F@2|Bacteria,1R7TT@1224|Proteobacteria,1RY7T@1236|Gammaproteobacteria,2Q1M0@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_7955_50 383381.EH30_03850 9.99e-27 105.0 2AKHC@1|root,31B9A@2|Bacteria,1RAQY@1224|Proteobacteria,2U6P6@28211|Alphaproteobacteria,2K4CU@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - k141_7955_51 1137268.AZXF01000004_gene2319 1.01e-32 120.0 COG0328@1|root,COG0328@2|Bacteria,2GK53@201174|Actinobacteria,4EQCT@85012|Streptosporangiales 201174|Actinobacteria L RNase H rnhA - 3.1.26.4 ko:K03469 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_H k141_7955_52 1493511.A0A0E3FMF4_9CAUD 3.5e-24 100.0 4QC5H@10239|Viruses,4QPNZ@28883|Caudovirales,4QHUK@10662|Myoviridae 10662|Myoviridae S sigma factor activity - - - - - - - - - - - - - k141_7955_55 1357423.S5MAP1_9CAUD 1.96e-57 197.0 4QAIK@10239|Viruses,4QUPH@35237|dsDNA viruses no RNA stage,4QPEB@28883|Caudovirales,4QHXI@10662|Myoviridae 10662|Myoviridae S hydrolase activity - - - - - - - - - - - - - k141_7955_57 445683.E3SK37_9CAUD 7.32e-109 344.0 4QAKZ@10239|Viruses,4QUSW@35237|dsDNA viruses no RNA stage,4QPYH@28883|Caudovirales,4QIYN@10662|Myoviridae 10662|Myoviridae S exonuclease activity - - - - - - - - - - - - - k141_33059_1 472759.Nhal_1111 6.5e-09 60.8 COG1214@1|root,COG1214@2|Bacteria,1MXPH@1224|Proteobacteria,1RPYX@1236|Gammaproteobacteria,1WX9X@135613|Chromatiales 135613|Chromatiales O PFAM Peptidase M22, glycoprotease - - - ko:K14742 - - - - ko00000,ko03016 - - - Peptidase_M22 k141_36457_2 1116375.VEJY3_21796 1.95e-74 223.0 COG2154@1|root,COG2154@2|Bacteria,1RH99@1224|Proteobacteria,1SAUS@1236|Gammaproteobacteria,1XXVD@135623|Vibrionales 135623|Vibrionales H pterin-4-alpha-carbinolamine dehydratase phhB GO:0003674,GO:0003824,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008124,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019438,GO:0019751,GO:0034311,GO:0034312,GO:0034641,GO:0042558,GO:0042559,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 4.2.1.96 ko:K01724 ko00790,map00790 - R04734 RC01208 ko00000,ko00001,ko01000,ko04147 - - - Pterin_4a k141_36457_3 1116375.VEJY3_21801 5.02e-183 509.0 COG3186@1|root,COG3186@2|Bacteria,1MU29@1224|Proteobacteria,1RQBJ@1236|Gammaproteobacteria,1XSTV@135623|Vibrionales 135623|Vibrionales E Phenylalanine-4-hydroxylase phhA GO:0003674,GO:0003824,GO:0004497,GO:0004505,GO:0006082,GO:0006520,GO:0006558,GO:0006559,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009987,GO:0016054,GO:0016491,GO:0016705,GO:0016714,GO:0017144,GO:0019439,GO:0019752,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902221,GO:1902222 1.14.16.1 ko:K00500 ko00360,ko00400,ko00790,ko01100,ko01230,map00360,map00400,map00790,map01100,map01230 - R01795,R07211 RC00490 ko00000,ko00001,ko01000 - - - Biopterin_H k141_36457_4 1116375.VEJY3_21806 0.0 1198.0 COG0365@1|root,COG0365@2|Bacteria,1MUX7@1224|Proteobacteria,1RPGT@1236|Gammaproteobacteria,1XVRA@135623|Vibrionales 135623|Vibrionales I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases acs-2 - 6.2.1.16 ko:K01907 ko00280,ko00650,map00280,map00650 - R01357 RC00004,RC00014 ko00000,ko00001,ko01000,ko01004 - - - ACAS_N,AMP-binding,AMP-binding_C k141_36457_5 1116375.VEJY3_21811 1.38e-112 325.0 COG0500@1|root,COG0500@2|Bacteria,1RJFG@1224|Proteobacteria,1S92D@1236|Gammaproteobacteria,1XUD5@135623|Vibrionales 135623|Vibrionales Q COG0500 SAM-dependent methyltransferases - - - - - - - - - - - - Methyltransf_12,Methyltransf_23 k141_36457_6 1116375.VEJY3_21816 4.37e-207 573.0 COG0583@1|root,COG0583@2|Bacteria,1NR3D@1224|Proteobacteria,1RWFP@1236|Gammaproteobacteria,1XV3V@135623|Vibrionales 135623|Vibrionales K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_36457_7 1116375.VEJY3_21821 2.84e-187 523.0 COG3965@1|root,COG3965@2|Bacteria,1RFDX@1224|Proteobacteria,1S556@1236|Gammaproteobacteria,1XSQT@135623|Vibrionales 135623|Vibrionales P Co Zn Cd cation transporters - - - - - - - - - - - - Cation_efflux k141_36457_8 223926.28808735 7.43e-195 543.0 COG0697@1|root,COG0697@2|Bacteria,1MVGC@1224|Proteobacteria,1RMXB@1236|Gammaproteobacteria,1XT7G@135623|Vibrionales 135623|Vibrionales EG of the drug metabolite transporter (DMT) superfamily yddG - - - - - - - - - - - EamA k141_36457_9 617140.AJZE01000093_gene2437 1.59e-08 52.0 2AWZE@1|root,31NXB@2|Bacteria,1QKKR@1224|Proteobacteria,1TIR2@1236|Gammaproteobacteria,1XZHK@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_36457_10 1116375.VEJY3_21831 5e-141 399.0 COG3155@1|root,COG3155@2|Bacteria,1MW2K@1224|Proteobacteria,1RMDJ@1236|Gammaproteobacteria,1XVK8@135623|Vibrionales 135623|Vibrionales Q Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate elbB - - - - - - - - - - - DJ-1_PfpI k141_36457_11 223926.28808732 7.44e-258 709.0 COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,1RMVU@1236|Gammaproteobacteria,1XV5C@135623|Vibrionales 135623|Vibrionales C alcohol dehydrogenase adhB - 1.1.1.1 ko:K13954 ko00010,ko00071,ko00350,ko00625,ko00626,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R04880,R05233,R05234,R06917,R06927 RC00050,RC00088,RC00099,RC00116,RC00649 ko00000,ko00001,ko01000 - - - Fe-ADH k141_36457_12 1116375.VEJY3_21841 1.35e-225 625.0 COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,1RNGN@1236|Gammaproteobacteria,1XV26@135623|Vibrionales 135623|Vibrionales G COG2133 Glucose sorbosone dehydrogenases - - - ko:K21430 - - - - ko00000,ko01000 - - - GSDH k141_17595_1 218284.CCDN010000005_gene3301 7.4e-174 497.0 COG2239@1|root,COG2239@2|Bacteria,1TP4V@1239|Firmicutes,4HASP@91061|Bacilli,1ZCSG@1386|Bacillus 91061|Bacilli P Acts as a magnesium transporter mgtE - - ko:K06213 - - - - ko00000,ko02000 1.A.26.1 - - CBS,MgtE,MgtE_N k141_24890_1 1294265.JCM21738_5500 9.38e-93 272.0 COG1595@1|root,COG1595@2|Bacteria,1V7IS@1239|Firmicutes,4HK4S@91061|Bacilli,1ZQI6@1386|Bacillus 91061|Bacilli K Sigma-70, region 4 - - - - - - - - - - - - Sigma70_r2,Sigma70_r4_2 k141_3334_2 1294265.JCM21738_2064 1.82e-06 48.1 COG0095@1|root,COG0095@2|Bacteria,1TQ5U@1239|Firmicutes,4HABG@91061|Bacilli,1ZBG2@1386|Bacillus 91061|Bacilli H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation lipM GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 6.3.1.20 ko:K03800 ko00785,ko01100,map00785,map01100 - R07770,R07771,R11143 RC00043,RC00070,RC00090,RC00992,RC02896 ko00000,ko00001,ko01000 - - - BPL_LplA_LipB k141_29594_1 1294265.JCM21738_1014 6.4e-120 347.0 COG1876@1|root,COG1876@2|Bacteria,1V1F7@1239|Firmicutes,4HBR1@91061|Bacilli,1ZCAG@1386|Bacillus 91061|Bacilli M D-alanyl-D-alanine carboxypeptidase yodJ - 3.4.17.14 ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 M00651 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 - - - VanY k141_17596_1 999141.GME_16782 4.94e-18 84.0 2AGS6@1|root,31703@2|Bacteria,1RJ9H@1224|Proteobacteria,1SKFX@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_10560_1 1449126.JQKL01000011_gene3542 7.38e-16 84.7 COG2333@1|root,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,249VR@186801|Clostridia,268TI@186813|unclassified Clostridiales 186801|Clostridia S Metallo-beta-lactamase superfamily - - - ko:K02238 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - Ada_Zn_binding,Lactamase_B k141_13052_1 1042377.AFPJ01000021_gene2138 1.13e-135 388.0 COG2022@1|root,COG2022@2|Bacteria,1N0N5@1224|Proteobacteria,1RMPD@1236|Gammaproteobacteria,465GP@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S thiG GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 ko:K03149 ko00730,ko01100,map00730,map01100 - R10247 RC03096,RC03097,RC03461 ko00000,ko00001,ko01000 - - - ThiG k141_13052_2 1279017.AQYJ01000026_gene394 2.57e-93 288.0 COG0352@1|root,COG0352@2|Bacteria,1QTW3@1224|Proteobacteria,1T1YB@1236|Gammaproteobacteria,46DEH@72275|Alteromonadaceae 1236|Gammaproteobacteria H Thiamine monophosphate synthase thiE - 2.5.1.3,2.7.1.49,2.7.4.7 ko:K00788,ko:K14153 ko00730,ko01100,map00730,map01100 M00127 R03223,R03471,R04509,R10712 RC00002,RC00017,RC00224,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 - - - Phos_pyr_kin,TMP-TENI k141_33060_1 1382315.JPOI01000001_gene2171 6.73e-43 149.0 COG0789@1|root,COG0789@2|Bacteria,1UYCQ@1239|Firmicutes,4HMK9@91061|Bacilli,1WFFN@129337|Geobacillus 91061|Bacilli K Protein of unknown function (DUF4004) - - - - - - - - - - - - DUF4004 k141_24892_1 218284.CCDN010000005_gene3161 4.06e-28 111.0 COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HB3V@91061|Bacilli,1ZB8V@1386|Bacillus 91061|Bacilli IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II alkK - - ko:K00666 - - - - ko00000,ko01000,ko01004 - - - AMP-binding,AMP-binding_C k141_21116_1 1042377.AFPJ01000012_gene1382 1.13e-22 95.5 COG1622@1|root,COG1622@2|Bacteria,1MWHZ@1224|Proteobacteria,1RP4H@1236|Gammaproteobacteria,465CG@72275|Alteromonadaceae 1236|Gammaproteobacteria C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) coxB - 1.9.3.1 ko:K02275 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.4,3.D.4.6 - - COX2,COX2_TM,Cytochrome_CBB3 k141_16486_2 218284.CCDN010000001_gene802 5.46e-132 381.0 28I64@1|root,2Z898@2|Bacteria,1TQX0@1239|Firmicutes,4HF76@91061|Bacilli,1ZEIB@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_29596_1 218284.CCDN010000002_gene2147 1.26e-114 346.0 2C593@1|root,2Z84R@2|Bacteria,1U546@1239|Firmicutes,4HEHB@91061|Bacilli,1ZMHC@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_35652_1 1307436.PBF_03675 2.36e-11 63.5 2DJA0@1|root,3055R@2|Bacteria,1TXRP@1239|Firmicutes,4I6TD@91061|Bacilli,1ZK1C@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_20165_1 1042377.AFPJ01000055_gene960 1.26e-74 241.0 COG5653@1|root,COG5653@2|Bacteria,1RAB9@1224|Proteobacteria,1SKTJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_6 k141_21117_1 313603.FB2170_00470 5.12e-54 176.0 COG0767@1|root,COG0767@2|Bacteria,4NF7X@976|Bacteroidetes,1HX62@117743|Flavobacteriia 976|Bacteroidetes Q Belongs to the MlaE permease family - - - ko:K02066 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaE k141_21117_2 907348.TresaDRAFT_1328 2.42e-05 47.4 COG1126@1|root,COG1126@2|Bacteria,2J5EK@203691|Spirochaetes 203691|Spirochaetes E ABC-type polar amino acid transport system ATPase component - - 3.6.3.21 ko:K02028 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran k141_30480_1 218284.CCDN010000001_gene689 1.94e-171 488.0 COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,4H9SR@91061|Bacilli,1ZBGE@1386|Bacillus 91061|Bacilli S AI-2E family transporter yrrI GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - - - - - - - - - - AI-2E_transport k141_17599_1 1168059.KB899087_gene15 2.67e-15 71.6 COG3415@1|root,COG3415@2|Bacteria,1RM6K@1224|Proteobacteria,2UDU9@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Transposase - - - - - - - - - - - - HTH_Tnp_IS630 k141_17599_2 1547437.LL06_26180 4.44e-104 305.0 COG3335@1|root,COG3335@2|Bacteria,1P76X@1224|Proteobacteria,2VBH8@28211|Alphaproteobacteria,43P72@69277|Phyllobacteriaceae 28211|Alphaproteobacteria L DDE superfamily endonuclease - - - - - - - - - - - - DDE_3 k141_35653_1 42565.FP66_07155 4.13e-19 83.2 COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,1RMAU@1236|Gammaproteobacteria,1XI77@135619|Oceanospirillales 135619|Oceanospirillales H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) ubiE - 2.1.1.163,2.1.1.201 ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116,M00117 R04990,R04993,R06859,R08774,R09736 RC00003,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000 - - - Ubie_methyltran k141_35653_2 42565.FP66_07160 1.89e-80 242.0 COG3165@1|root,COG3165@2|Bacteria,1R1CM@1224|Proteobacteria,1S1SM@1236|Gammaproteobacteria,1XMBP@135619|Oceanospirillales 135619|Oceanospirillales S protein conserved in bacteria - - - ko:K03690 - - - - ko00000 - - - SCP2 k141_16487_1 266117.Rxyl_0471 7.29e-57 193.0 COG0665@1|root,COG0665@2|Bacteria,2I9WR@201174|Actinobacteria,4CR0T@84995|Rubrobacteria 84995|Rubrobacteria C FAD dependent oxidoreductase - - 1.5.3.1 ko:K00301 ko00260,ko01100,map00260,map01100 - R00610 RC00060,RC00557 ko00000,ko00001,ko01000 - - - DAO k141_3336_1 218284.CCDN010000001_gene1287 4.1e-89 267.0 COG0159@1|root,COG0159@2|Bacteria,1TPXA@1239|Firmicutes,4HFQ8@91061|Bacilli,1ZC5U@1386|Bacillus 91061|Bacilli E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate trpA - 4.2.1.20 ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - Trp_syntA k141_24895_2 218284.CCDN010000007_gene3985 1.9e-46 152.0 COG0394@1|root,COG0394@2|Bacteria,1VA05@1239|Firmicutes,4HKBQ@91061|Bacilli,1ZH51@1386|Bacillus 91061|Bacilli T Belongs to the low molecular weight phosphotyrosine protein phosphatase family ywlE - 3.1.3.48,3.9.1.2 ko:K01104,ko:K20201 - - - - ko00000,ko01000 - - - LMWPc k141_15175_1 574376.BAMA_05440 4.27e-11 67.8 2DH6Y@1|root,2ZYKQ@2|Bacteria,1V3RR@1239|Firmicutes,4HHKE@91061|Bacilli,1ZBHI@1386|Bacillus 91061|Bacilli S Spore germination B3/ GerAC like, C-terminal gerC - - ko:K06308 - - - - ko00000 - - - Spore_GerAC k141_17600_1 218284.CCDN010000001_gene980 6.03e-128 384.0 COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,4HADT@91061|Bacilli,1ZAZA@1386|Bacillus 91061|Bacilli KT Transcriptional regulator bkdR - - - - - - - - - - - DapB_N,HTH_8,PAS,Sigma54_activat k141_35654_1 218284.CCDN010000001_gene547 6.85e-91 269.0 COG1335@1|root,COG1335@2|Bacteria,1V2DX@1239|Firmicutes,4HJMV@91061|Bacilli,1ZGBB@1386|Bacillus 91061|Bacilli Q Isochorismatase family - - - - - - - - - - - - Isochorismatase k141_37739_2 223926.28809354 6.88e-71 215.0 COG1661@1|root,COG1661@2|Bacteria,1RIME@1224|Proteobacteria,1S71M@1236|Gammaproteobacteria,1XXZ3@135623|Vibrionales 135623|Vibrionales S DNA-binding protein with PD1-like DNA-binding motif - - - ko:K06934 - - - - ko00000 - - - DUF296 k141_37739_3 1116375.VEJY3_20266 2.1e-221 612.0 COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,1RP6Z@1236|Gammaproteobacteria,1XUBQ@135623|Vibrionales 135623|Vibrionales E Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family ilvE - 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_4 k141_37739_4 1280001.BAOA01000070_gene2866 6.02e-55 173.0 COG2146@1|root,COG2146@2|Bacteria,1MZBY@1224|Proteobacteria,1S9F1@1236|Gammaproteobacteria,1XYHD@135623|Vibrionales 135623|Vibrionales P COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases - - 1.7.1.15 ko:K00363 ko00910,ko01120,map00910,map01120 M00530 R00787 RC00176 ko00000,ko00001,ko00002,ko01000 - - - Rieske_2 k141_37739_5 223926.28809356 0.0 1311.0 COG1251@1|root,COG1251@2|Bacteria,1MW58@1224|Proteobacteria,1RNGY@1236|Gammaproteobacteria,1XUM5@135623|Vibrionales 135623|Vibrionales C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family - - 1.7.1.15 ko:K00362 ko00910,ko01120,map00910,map01120 M00530 R00787 RC00176 ko00000,ko00001,ko00002,ko01000 - - - Fer2_BFD,NIR_SIR,NIR_SIR_ferr,Pyr_redox_2 k141_10562_1 1294265.JCM21738_370 1.7e-110 322.0 COG0136@1|root,COG0136@2|Bacteria,1TPC6@1239|Firmicutes,4HA9H@91061|Bacilli,1ZAVS@1386|Bacillus 91061|Bacilli E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate asd - 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC k141_24896_1 218284.CCDN010000001_gene680 3.55e-182 515.0 COG2256@1|root,COG2256@2|Bacteria,1TPVV@1239|Firmicutes,4HAIS@91061|Bacilli,1ZBCW@1386|Bacillus 91061|Bacilli L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase rarA - - ko:K07478 - - - - ko00000 - - - AAA,AAA_assoc_2,MgsA_C,RuvB_N k141_13055_3 218284.CCDN010000007_gene3804 3.69e-43 149.0 COG0668@1|root,COG0668@2|Bacteria,1TR9Z@1239|Firmicutes,4HCB8@91061|Bacilli,1ZCW4@1386|Bacillus 91061|Bacilli M Mechanosensitive ion channel ykuT - - ko:K22044 - - - - ko00000,ko02000 1.A.23.3 - - MS_channel k141_35655_1 568816.Acin_0336 3.23e-28 108.0 COG0735@1|root,COG0735@2|Bacteria,1V400@1239|Firmicutes,4H4M6@909932|Negativicutes 909932|Negativicutes P Belongs to the Fur family perR - - ko:K09825 - - - - ko00000,ko03000 - - - FUR k141_10563_1 218284.CCDN010000002_gene2813 1.09e-86 270.0 COG2132@1|root,COG2132@2|Bacteria,1TQSU@1239|Firmicutes,4HDD6@91061|Bacilli,1ZD48@1386|Bacillus 91061|Bacilli Q multicopper oxidases cotA GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016679,GO:0016682,GO:0016722,GO:0052716,GO:0055114 1.16.3.3 ko:K06324 - - - - ko00000,ko01000 - - - Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3 k141_29598_1 1279017.AQYJ01000021_gene2852 2.4e-138 405.0 COG0738@1|root,COG0738@2|Bacteria,1MXDC@1224|Proteobacteria,1RQX9@1236|Gammaproteobacteria,463ZE@72275|Alteromonadaceae 1236|Gammaproteobacteria G glucose galactose transporter gluP - - ko:K02429 - - - - ko00000,ko02000 2.A.1.7 - - MFS_1 k141_21120_2 997296.PB1_15479 2.06e-59 192.0 COG0826@1|root,COG0826@2|Bacteria,1TQIZ@1239|Firmicutes,4HA2T@91061|Bacilli,1ZAXB@1386|Bacillus 91061|Bacilli O Peptidase U32 yrrN - - ko:K08303 ko05120,map05120 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_U32 k141_28181_1 1250005.PHEL85_1697 7.21e-25 104.0 COG4659@1|root,COG4659@2|Bacteria,4NQKH@976|Bacteroidetes,1IAXX@117743|Flavobacteriia 976|Bacteroidetes U Part of a membrane complex involved in electron transport rnfG - - ko:K03612 - - - - ko00000 - - - FMN_bind k141_4542_1 1307436.PBF_04335 3.02e-204 579.0 2DB9U@1|root,2Z7Z6@2|Bacteria,1TR67@1239|Firmicutes,4HCTZ@91061|Bacilli,1ZEZR@1386|Bacillus 91061|Bacilli S Phage portal protein, SPP1 Gp6-like - - - - - - - - - - - - Phage_prot_Gp6 k141_4542_4 1307436.PBF_04350 3.85e-82 249.0 29A6A@1|root,2ZX7B@2|Bacteria,1V4X8@1239|Firmicutes,4HJHK@91061|Bacilli,1ZGI9@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF4355) - - - - - - - - - - - - DUF4355 k141_37741_2 1405.DJ92_4063 7.29e-31 117.0 COG1387@1|root,COG1387@2|Bacteria,1UZ0M@1239|Firmicutes,4HAUH@91061|Bacilli,1ZE5C@1386|Bacillus 91061|Bacilli E COG1387 Histidinol phosphatase and related hydrolases of the PHP family hisJ - 3.1.3.15 ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R03013 RC00017 ko00000,ko00001,ko00002,ko01000 - - - PHP k141_24897_1 218284.CCDN010000001_gene1064 2.42e-180 518.0 COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HBZ0@91061|Bacilli,1ZAQC@1386|Bacillus 91061|Bacilli T Histidine kinase resE - 2.7.13.3 ko:K07651 ko02020,map02020 M00458 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,PAS,PAS_4 k141_10739_3 1453501.JELR01000002_gene607 2.64e-87 263.0 COG3150@1|root,COG3150@2|Bacteria,1MVJF@1224|Proteobacteria,1S5WF@1236|Gammaproteobacteria,4674V@72275|Alteromonadaceae 1236|Gammaproteobacteria S esterase yqiA GO:0003674,GO:0003824,GO:0016787,GO:0016788 - ko:K07000 - - - - ko00000 - - - UPF0227 k141_10739_5 1279017.AQYJ01000028_gene2257 4.44e-63 201.0 COG1247@1|root,COG1247@2|Bacteria,1QVS0@1224|Proteobacteria,1T2IG@1236|Gammaproteobacteria,46DD0@72275|Alteromonadaceae 1236|Gammaproteobacteria M Acetyltransferase (GNAT) family - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_3 k141_10739_6 1042377.AFPJ01000024_gene752 1.47e-238 667.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,464WF@72275|Alteromonadaceae 1236|Gammaproteobacteria JKL DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA rhlE - 3.6.4.13 ko:K11927 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - DEAD,Helicase_C k141_10739_8 1282356.H045_21185 4.33e-26 100.0 COG3063@1|root,COG3063@2|Bacteria,1N2T8@1224|Proteobacteria,1S9R8@1236|Gammaproteobacteria,1YQIB@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria NU Tetratricopeptide repeat - - - - - - - - - - - - TPR_14,TPR_16,TPR_19,TPR_2 k141_4831_1 1384049.CD29_16360 3.96e-41 141.0 COG2318@1|root,COG2318@2|Bacteria,1V31G@1239|Firmicutes,4HHZ5@91061|Bacilli,3IXYI@400634|Lysinibacillus 91061|Bacilli S DinB family - - - - - - - - - - - - DinB k141_25007_1 218284.CCDN010000002_gene2692 3.15e-76 235.0 COG0491@1|root,COG0491@2|Bacteria,1U98Y@1239|Firmicutes,4HDNC@91061|Bacilli,1ZFJX@1386|Bacillus 91061|Bacilli S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B k141_32139_1 218284.CCDN010000002_gene2798 8.65e-115 368.0 COG0308@1|root,COG0577@1|root,COG4591@1|root,COG0308@2|Bacteria,COG0577@2|Bacteria,COG4591@2|Bacteria,1TSZH@1239|Firmicutes,4HCKC@91061|Bacilli 91061|Bacilli MV FtsX-like permease family - - - - - - - - - - - - FtsX k141_16679_1 994479.GL877882_gene6710 6.48e-61 204.0 COG0166@1|root,COG0166@2|Bacteria,2GJG0@201174|Actinobacteria,4EACZ@85010|Pseudonocardiales 201174|Actinobacteria G Phosphoglucose isomerase pgi - 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGI k141_22663_1 555500.I215_06642 4.15e-05 48.1 COG2801@1|root,COG2801@2|Bacteria,4NF3Q@976|Bacteroidetes,1HZT4@117743|Flavobacteriia 976|Bacteroidetes L COG2801 Transposase and inactivated derivatives - - - ko:K07497 - - - - ko00000 - - - HTH_21,rve,rve_2 k141_22663_2 666686.B1NLA3E_21570 1.69e-49 158.0 COG2963@1|root,COG2963@2|Bacteria,1VP6M@1239|Firmicutes,4HRHX@91061|Bacilli,1ZIZ1@1386|Bacillus 91061|Bacilli L COG2963 Transposase and inactivated derivatives - - - ko:K07483 - - - - ko00000 - - - HTH_Tnp_1 k141_10740_1 203267.TWT_053 7.88e-06 49.3 COG0500@1|root,COG2226@2|Bacteria,2GKFZ@201174|Actinobacteria 201174|Actinobacteria H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) menG - 2.1.1.163,2.1.1.201 ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116,M00117 R04990,R04993,R06859,R08774,R09736 RC00003,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000 - - - Ubie_methyltran k141_10740_2 1125863.JAFN01000001_gene2808 5.76e-27 111.0 COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,42M1C@68525|delta/epsilon subdivisions,2WIZQ@28221|Deltaproteobacteria 28221|Deltaproteobacteria C D-isomer specific 2-hydroxyacid dehydrogenase - - 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C,ACT k141_1220_2 1279017.AQYJ01000020_gene1363 2.57e-11 62.0 COG1595@1|root,COG1595@2|Bacteria,1N748@1224|Proteobacteria,1SEDH@1236|Gammaproteobacteria,468VM@72275|Alteromonadaceae 1236|Gammaproteobacteria K ECF sigma factor - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_15539_1 218284.CCDN010000001_gene316 8.07e-49 160.0 29RJD@1|root,30CNG@2|Bacteria,1UA4U@1239|Firmicutes,4IKF4@91061|Bacilli,1ZGTM@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_15539_2 218284.CCDN010000001_gene315 1.86e-74 234.0 COG1473@1|root,COG1473@2|Bacteria,1TQ7B@1239|Firmicutes,4HAIK@91061|Bacilli,1ZDIH@1386|Bacillus 91061|Bacilli S amidohydrolase hmrA - - ko:K21613 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 k141_10741_1 1121921.KB898710_gene465 3.02e-106 320.0 COG3534@1|root,COG3534@2|Bacteria,1PPWJ@1224|Proteobacteria,1RQ0J@1236|Gammaproteobacteria,2PMUH@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria G Alpha-L-arabinofuranosidase C-terminus abfA - 3.2.1.55 ko:K01209 ko00520,map00520 - R01762 - ko00000,ko00001,ko01000 - GH51 - Alpha-L-AF_C k141_21478_2 1279017.AQYJ01000029_gene3682 9.63e-229 635.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RQ5M@1236|Gammaproteobacteria,464GY@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1960 Acyl-CoA dehydrogenases - - 1.3.8.7 ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_21478_3 646529.Desaci_0431 0.000598 48.9 COG0439@1|root,COG1038@1|root,COG4799@1|root,COG0439@2|Bacteria,COG1038@2|Bacteria,COG4799@2|Bacteria,1TP16@1239|Firmicutes,25E48@186801|Clostridia,26111@186807|Peptococcaceae 186801|Clostridia I TIGRFAM acetyl-CoA carboxylase, biotin carboxylase - - 6.3.4.14,6.4.1.2,6.4.1.3 ko:K01961,ko:K01965 ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00373,M00376,M00741 R00742,R01859,R04385 RC00040,RC00097,RC00253,RC00367,RC00609 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,Carboxyl_trans k141_4832_1 42565.FP66_01805 3.9e-88 266.0 COG3332@1|root,COG3332@2|Bacteria,1RDBS@1224|Proteobacteria,1S43Y@1236|Gammaproteobacteria,1XJH6@135619|Oceanospirillales 135619|Oceanospirillales S Transport and Golgi organisation 2 - - - - - - - - - - - - TANGO2 k141_4832_2 42565.FP66_01800 6.19e-17 79.7 COG3605@1|root,COG3605@2|Bacteria,1QTTV@1224|Proteobacteria,1T1H2@1236|Gammaproteobacteria,1XHCB@135619|Oceanospirillales 135619|Oceanospirillales T Belongs to the PEP-utilizing enzyme family ptsP - 2.7.3.9 ko:K08484 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 - - - GAF,GAF_2,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C k141_23820_1 218284.CCDN010000005_gene3198 3e-149 422.0 28PM4@1|root,2ZCA8@2|Bacteria,1V1PA@1239|Firmicutes,4HFNN@91061|Bacilli,1ZG8T@1386|Bacillus 91061|Bacilli S YtkA-like ytkA - - - - - - - - - - - PKD,YtkA k141_26222_1 218284.CCDN010000002_gene2134 3.76e-32 113.0 2E9DY@1|root,333MH@2|Bacteria,1VEUX@1239|Firmicutes,4HPGE@91061|Bacilli,1ZITW@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_19068_1 1517681.HW45_09875 5.25e-226 637.0 COG1070@1|root,COG1070@2|Bacteria,1MWS5@1224|Proteobacteria,1RP2G@1236|Gammaproteobacteria,1XW1B@135623|Vibrionales 135623|Vibrionales G FGGY family of carbohydrate kinases, N-terminal domain - - 2.7.1.53 ko:K00880 ko00040,ko00053,map00040,map00053 - R01901,R07127 RC00002,RC00017,RC00538 ko00000,ko00001,ko01000 - - - FGGY_C,FGGY_N k141_19068_2 1517681.HW45_09870 2.4e-194 540.0 COG1830@1|root,COG1830@2|Bacteria,1MWJW@1224|Proteobacteria,1RYC1@1236|Gammaproteobacteria,1XVZP@135623|Vibrionales 135623|Vibrionales G Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - - - - - - - - - - DeoC k141_19068_3 1517681.HW45_09865 0.0 883.0 COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,1RMGP@1236|Gammaproteobacteria,1XW95@135623|Vibrionales 135623|Vibrionales C Glycerol-3-phosphate dehydrogenase - - 1.1.5.3 ko:K00111 ko00564,ko01110,map00564,map01110 - R00848 RC00029 ko00000,ko00001,ko01000 - - - DAO,DAO_C k141_19068_4 1517681.HW45_09860 4.44e-209 581.0 COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,1RPX5@1236|Gammaproteobacteria,1XV22@135623|Vibrionales 135623|Vibrionales C oxidoreductases (related to aryl-alcohol dehydrogenases) - - - - - - - - - - - - Aldo_ket_red k141_19068_5 1517681.HW45_09855 8.99e-193 539.0 COG2390@1|root,COG2390@2|Bacteria,1PJS0@1224|Proteobacteria,1TF7B@1236|Gammaproteobacteria,1XXK7@135623|Vibrionales 135623|Vibrionales K Transcriptional regulator - - - - - - - - - - - - Sugar-bind k141_19068_6 1517681.HW45_09850 2.98e-225 623.0 COG1879@1|root,COG1879@2|Bacteria,1QKY2@1224|Proteobacteria,1TJ44@1236|Gammaproteobacteria,1Y0H8@135623|Vibrionales 135623|Vibrionales G Ribose ABC transporter substrate-binding protein - - - - - - - - - - - - Peripla_BP_4 k141_19068_7 1517681.HW45_09845 1.49e-222 623.0 COG1129@1|root,COG1129@2|Bacteria,1MU22@1224|Proteobacteria,1RMCH@1236|Gammaproteobacteria,1XZSK@135623|Vibrionales 135623|Vibrionales G ATPases associated with a variety of cellular activities - - 3.6.3.17 ko:K10441 ko02010,map02010 M00212 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - ABC_tran k141_22665_1 292459.STH1041 2.25e-06 50.4 COG0745@1|root,COG0745@2|Bacteria,1TPRU@1239|Firmicutes,24843@186801|Clostridia 186801|Clostridia KT response regulator receiver - - - - - - - - - - - - Response_reg,Trans_reg_C k141_22665_2 485916.Dtox_4336 9.45e-22 87.8 2C82G@1|root,32RK9@2|Bacteria,1VZ8X@1239|Firmicutes 1239|Firmicutes S Protein of unknown function (DUF4242) - - - - - - - - - - - - DUF4242 k141_13163_1 1042377.AFPJ01000036_gene1236 2.13e-28 112.0 COG0705@1|root,COG0705@2|Bacteria,1N8NS@1224|Proteobacteria,1SD4M@1236|Gammaproteobacteria,467DU@72275|Alteromonadaceae 1236|Gammaproteobacteria S membrane protein (homolog of Drosophila rhomboid) - - - - - - - - - - - - Rhomboid k141_13163_2 1129794.C427_2672 1.84e-67 213.0 COG0656@1|root,COG0656@2|Bacteria,1MWFS@1224|Proteobacteria,1RMX6@1236|Gammaproteobacteria,467B4@72275|Alteromonadaceae 1236|Gammaproteobacteria S Aldo/keto reductase family dkgA GO:0003674,GO:0003824,GO:0004033,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0008106,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0042180,GO:0042182,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0051596,GO:0055114,GO:0071704,GO:1901575 1.1.1.307,1.1.1.346 ko:K06221,ko:K17743 ko00040,ko01100,map00040,map01100 - R01431,R08878,R09477 RC00089,RC00133 ko00000,ko00001,ko01000 - - iECH74115_1262.ECH74115_4323,iECSP_1301.ECSP_3988 Aldo_ket_red k141_28604_2 1453501.JELR01000001_gene1881 2.13e-88 271.0 COG0025@1|root,COG0025@2|Bacteria,1MW5T@1224|Proteobacteria,1RPH6@1236|Gammaproteobacteria,467E9@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0025 NhaP-type Na H and K H antiporters nhaP - - ko:K03316 - - - - ko00000 2.A.36 - - Na_H_Exchanger,cNMP_binding k141_33343_1 1453501.JELR01000002_gene617 1.76e-220 624.0 COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,1RQQV@1236|Gammaproteobacteria,46448@72275|Alteromonadaceae 1236|Gammaproteobacteria MU COG1538 Outer membrane protein tolC - - ko:K12340 ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133 M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko02044 1.B.17,2.A.6.2 - - OEP k141_3638_1 1116375.VEJY3_06365 2.07e-237 654.0 COG2988@1|root,COG2988@2|Bacteria,1MW1T@1224|Proteobacteria,1RQPG@1236|Gammaproteobacteria,1XU9R@135623|Vibrionales 135623|Vibrionales E Belongs to the AspA AstE family. Succinylglutamate desuccinylase subfamily astE GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016787,GO:0016788,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.1.96 ko:K05526 ko00330,ko01100,map00330,map01100 - R00411 RC00064,RC00090 ko00000,ko00001,ko01000 - - - AstE_AspA k141_21479_1 379066.GAU_1774 3.01e-75 233.0 COG0528@1|root,COG0528@2|Bacteria,1ZSY2@142182|Gemmatimonadetes 142182|Gemmatimonadetes F Catalyzes the reversible phosphorylation of UMP to UDP pyrH - 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 - R00158 RC00002 ko00000,ko00001,ko01000 - - - AA_kinase k141_14331_1 1453501.JELR01000002_gene897 1.65e-106 332.0 COG0542@1|root,COG0542@2|Bacteria,1MVBH@1224|Proteobacteria,1RMZH@1236|Gammaproteobacteria,4648I@72275|Alteromonadaceae 1236|Gammaproteobacteria O Belongs to the ClpA ClpB family clpV - - ko:K11907 ko02025,ko03070,map02025,map03070 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - AAA,AAA_2,ClpB_D2-small,Clp_N k141_36898_1 1116375.VEJY3_03805 2.72e-162 456.0 COG2267@1|root,COG2267@2|Bacteria,1QUFS@1224|Proteobacteria,1T1XF@1236|Gammaproteobacteria,1XV01@135623|Vibrionales 135623|Vibrionales I PGAP1-like protein - - - ko:K01175 - - - - ko00000,ko01000 - - - Abhydrolase_1,Abhydrolase_6 k141_36898_2 1280001.BAOA01000064_gene2612 4.48e-44 143.0 2E5H5@1|root,3308N@2|Bacteria,1NB87@1224|Proteobacteria,1SDHI@1236|Gammaproteobacteria,1XYD8@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF2788) - - - - - - - - - - - - DUF2788 k141_36898_3 223926.28805821 5.48e-128 363.0 COG0716@1|root,COG0716@2|Bacteria,1MX7F@1224|Proteobacteria,1RMNT@1236|Gammaproteobacteria,1XT3A@135623|Vibrionales 135623|Vibrionales C Low-potential electron donor to a number of redox enzymes fldA - - ko:K03839 - - - - ko00000 - - - Flavodoxin_1 k141_36898_4 1116375.VEJY3_03790 3.34e-115 330.0 COG2050@1|root,COG2050@2|Bacteria,1RH0Z@1224|Proteobacteria,1S5W6@1236|Gammaproteobacteria,1XVCD@135623|Vibrionales 135623|Vibrionales Q Domain of unknown function (DUF4442) - - - - - - - - - - - - DUF4442 k141_36898_5 1116375.VEJY3_03785 1.04e-107 310.0 COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,1S4H7@1236|Gammaproteobacteria,1XUH6@135623|Vibrionales 135623|Vibrionales K Belongs to the Fur family fur GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - ko:K03711 - - - - ko00000,ko03000 - - - FUR k141_36898_6 1219076.N646_2984 0.0 1114.0 COG0008@1|root,COG0008@2|Bacteria,1MUC8@1224|Proteobacteria,1RQ7G@1236|Gammaproteobacteria,1XV77@135623|Vibrionales 135623|Vibrionales J COG0008 Glutamyl- and glutaminyl-tRNA synthetases glnS GO:0003674,GO:0003824,GO:0004812,GO:0004819,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006425,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.18 ko:K01886 ko00970,ko01100,map00970,map01100 M00359,M00360 R03652 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1c,tRNA-synt_1c_C k141_6032_3 1232410.KI421413_gene959 1.37e-59 195.0 COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,42M1J@68525|delta/epsilon subdivisions,2WIQR@28221|Deltaproteobacteria,43SBN@69541|Desulfuromonadales 28221|Deltaproteobacteria D TIGRFAM cell shape determining protein, MreB Mrl family mreB - - ko:K03569 - - - - ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 - - MreB_Mbl k141_13180_1 218284.CCDN010000001_gene1275 3.41e-77 234.0 COG0671@1|root,COG0671@2|Bacteria,1VF2U@1239|Firmicutes,4HNXR@91061|Bacilli,1ZIEP@1386|Bacillus 91061|Bacilli I COG0671 Membrane-associated phospholipid phosphatase pap2c - 3.6.1.27 ko:K19302 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - PAP2 k141_13180_2 218284.CCDN010000001_gene1274 6e-33 121.0 COG1273@1|root,COG1273@2|Bacteria,1TSY5@1239|Firmicutes,4HC5V@91061|Bacilli,1ZB9J@1386|Bacillus 91061|Bacilli L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD ku GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0097159,GO:1901363 - ko:K10979 ko03450,map03450 - - - ko00000,ko00001,ko03400 - - - Ku k141_31000_1 218284.CCDN010000005_gene3462 5.66e-120 352.0 COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,4HA13@91061|Bacilli,1ZAWQ@1386|Bacillus 91061|Bacilli E Aminotransferase yugH - - ko:K10907 - - - - ko00000,ko01000,ko01007 - - - Aminotran_1_2 k141_11953_1 218284.CCDN010000001_gene94 1.93e-213 603.0 COG4365@1|root,COG4365@2|Bacteria,1TQ2P@1239|Firmicutes,4HA2Z@91061|Bacilli,1ZBMV@1386|Bacillus 91061|Bacilli S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH bshC - - ko:K22136 - - - - ko00000 - - - BshC k141_10756_2 665959.HMPREF1013_03297 2.03e-140 402.0 COG2334@1|root,COG2334@2|Bacteria,1UZ9H@1239|Firmicutes,4HEG1@91061|Bacilli,1ZDST@1386|Bacillus 91061|Bacilli S Ecdysteroid kinase - - - - - - - - - - - - APH k141_34564_1 42565.FP66_13535 8.8e-113 326.0 COG0762@1|root,COG0762@2|Bacteria,1RCZV@1224|Proteobacteria,1S6DW@1236|Gammaproteobacteria,1XKTT@135619|Oceanospirillales 135619|Oceanospirillales S Integral membrane protein - - - ko:K02221 - - - - ko00000,ko02044 - - - YGGT k141_9585_1 218284.CCDN010000001_gene382 4.05e-130 375.0 COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,4H9ZW@91061|Bacilli,1ZB08@1386|Bacillus 91061|Bacilli S COG0618 Exopolyphosphatase-related proteins nrnA - 3.1.13.3,3.1.3.7 ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 - R00188,R00508 RC00078 ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1 k141_28624_3 379731.PST_0059 2.97e-19 81.6 COG0346@1|root,COG0346@2|Bacteria,1N0CH@1224|Proteobacteria,1S8U7@1236|Gammaproteobacteria,1Z32W@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria E Glyoxalase-like domain - - - - - - - - - - - - Glyoxalase k141_35744_1 1408422.JHYF01000043_gene3830 2.3e-12 60.5 2BEY2@1|root,328PR@2|Bacteria,1UUMT@1239|Firmicutes,2576E@186801|Clostridia,36TJM@31979|Clostridiaceae 186801|Clostridia - - - - - - - - - - - - - - - k141_29787_1 42565.FP66_05340 4.83e-120 351.0 COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,1MWHZ@1224|Proteobacteria,1RP4H@1236|Gammaproteobacteria,1XIU7@135619|Oceanospirillales 135619|Oceanospirillales C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) coxB - 1.9.3.1 ko:K02275 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.4,3.D.4.6 - - COX2,COX2_TM,Cytochrome_CBB3 k141_19091_1 1294265.JCM21738_3564 4.87e-106 313.0 COG2385@1|root,COG2385@2|Bacteria,1TQSI@1239|Firmicutes,4HCE3@91061|Bacilli,1ZBNU@1386|Bacillus 91061|Bacilli D Stage II sporulation protein D spoIID GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 - ko:K06381 - - - - ko00000 - - - SpoIID k141_3662_1 1122603.ATVI01000007_gene1711 5.16e-07 58.5 28JTF@1|root,2Z9IQ@2|Bacteria,1R728@1224|Proteobacteria,1SJF5@1236|Gammaproteobacteria,1X4II@135614|Xanthomonadales 135614|Xanthomonadales S Aerotolerance regulator N-terminal - - - - - - - - - - - - BatA k141_17941_1 1379270.AUXF01000004_gene3278 1.12e-64 207.0 COG0601@1|root,COG0601@2|Bacteria,1ZSXJ@142182|Gemmatimonadetes 142182|Gemmatimonadetes U Binding-protein-dependent transport system inner membrane component - - - ko:K02033 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 k141_13181_1 218284.CCDN010000002_gene2011 1.7e-11 61.6 COG5506@1|root,COG5506@2|Bacteria,1VFCV@1239|Firmicutes,4HNNE@91061|Bacilli,1ZI9H@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF1694) XK27_05190 - - - - - - - - - - - DUF1694 k141_8427_1 1334046.AYTB01000008_gene2323 8.25e-74 258.0 COG1196@1|root,COG5283@1|root,COG5412@1|root,COG1196@2|Bacteria,COG5283@2|Bacteria,COG5412@2|Bacteria,1TQ28@1239|Firmicutes,4HCMX@91061|Bacilli,26FWK@186818|Planococcaceae 91061|Bacilli D Phage tail tape measure protein, TP901 family - - - - - - - - - - - - PhageMin_Tail k141_6033_1 218284.CCDN010000005_gene3190 1.51e-116 337.0 COG1335@1|root,COG1335@2|Bacteria,1V70H@1239|Firmicutes,4HJXC@91061|Bacilli,1ZG9B@1386|Bacillus 91061|Bacilli Q Isochorismatase family - - - - - - - - - - - - Isochorismatase k141_6033_2 218284.CCDN010000005_gene3191 5.42e-33 118.0 COG2329@1|root,COG2329@2|Bacteria,1V501@1239|Firmicutes,4HHA2@91061|Bacilli,1ZGDD@1386|Bacillus 91061|Bacilli S enzyme involved in biosynthesis of extracellular polysaccharides traP GO:0005575,GO:0016020 1.14.99.57 ko:K21481 - - - - ko00000,ko01000 - - - ABM k141_21499_2 218284.CCDN010000005_gene3338 7.72e-59 183.0 2DB6C@1|root,32TWU@2|Bacteria,1VC4Z@1239|Firmicutes,4HKEX@91061|Bacilli,1ZGUZ@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3243) yflH - - - - - - - - - - - DUF3243 k141_21499_3 1121091.AUMP01000027_gene775 1.46e-68 212.0 COG1764@1|root,COG1764@2|Bacteria,1V41Y@1239|Firmicutes,4HH9W@91061|Bacilli 91061|Bacilli O redox protein, regulator of disulfide bond formation ymaD - - - - - - - - - - - OsmC k141_4846_1 1453501.JELR01000001_gene2494 1.06e-217 630.0 COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,1T4K6@1236|Gammaproteobacteria,46DC0@72275|Alteromonadaceae 1236|Gammaproteobacteria KLT Sulfatase-modifying factor enzyme 1 ppkA - 2.7.11.1 ko:K11912 ko02025,ko03070,map02025,map03070 - - - ko00000,ko00001,ko01000,ko01001,ko02044 - - - FGE-sulfatase,PEGA,Pkinase k141_20267_1 42565.FP66_06215 2.3e-53 185.0 COG3243@1|root,COG3243@2|Bacteria,1MUNE@1224|Proteobacteria,1RNZI@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Protein of unknown function (DUF3141) - - - - - - - - - - - - DUF3141 k141_8428_1 441769.ABFU01000042_gene3358 9.39e-66 201.0 COG1733@1|root,COG1733@2|Bacteria,1V43K@1239|Firmicutes,4HH01@91061|Bacilli,1ZGIV@1386|Bacillus 91061|Bacilli K Transcriptional regulator ytcD - - - - - - - - - - - HxlR k141_6034_1 1042377.AFPJ01000043_gene932 2.03e-69 232.0 COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,1RMGA@1236|Gammaproteobacteria,46478@72275|Alteromonadaceae 1236|Gammaproteobacteria L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG GO:0003674,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB_bind,DnaG_DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2 k141_25020_1 351348.Maqu_2179 1.52e-10 59.3 COG3526@1|root,COG3526@2|Bacteria,1MZ5V@1224|Proteobacteria,1S8S8@1236|Gammaproteobacteria,468BE@72275|Alteromonadaceae 1236|Gammaproteobacteria O protein conserved in bacteria - - - ko:K07401 - - - - ko00000 - - - Rdx k141_25020_2 649639.Bcell_2134 2.8e-56 185.0 COG0709@1|root,COG0709@2|Bacteria,1TQCJ@1239|Firmicutes,4HB6P@91061|Bacilli,1ZCAH@1386|Bacillus 91061|Bacilli E Synthesizes selenophosphate from selenide and ATP selD - 2.7.9.3 ko:K01008 ko00450,ko01100,map00450,map01100 - R03595 RC00002,RC02878 ko00000,ko00001,ko01000,ko03016 - - - AIRS,AIRS_C k141_3663_1 1279017.AQYJ01000024_gene1061 6.56e-77 230.0 COG0103@1|root,COG0103@2|Bacteria,1RD4A@1224|Proteobacteria,1S3Q7@1236|Gammaproteobacteria,466SE@72275|Alteromonadaceae 1236|Gammaproteobacteria J Belongs to the universal ribosomal protein uS9 family rpsI GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02996 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S9 k141_9586_1 218284.CCDN010000006_gene3512 3.03e-166 479.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HB0J@91061|Bacilli,1ZBUU@1386|Bacillus 91061|Bacilli I acyl-CoA dehydrogenase fadE - 1.3.8.1 ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 - R01175,R01178,R02661,R03172,R04751 RC00052,RC00068,RC00076,RC00120,RC00148 ko00000,ko00001,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_34566_1 1294265.JCM21738_1837 3.92e-109 328.0 COG1251@1|root,COG1251@2|Bacteria,1TQYX@1239|Firmicutes,4HASM@91061|Bacilli,1ZQ9P@1386|Bacillus 91061|Bacilli C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family nirB - 1.7.1.15 ko:K00362 ko00910,ko01120,map00910,map01120 M00530 R00787 RC00176 ko00000,ko00001,ko00002,ko01000 - - - Fer2_BFD,NIR_SIR,NIR_SIR_ferr,Pyr_redox_2 k141_34566_2 1294265.JCM21738_1838 6.75e-39 133.0 COG4768@1|root,COG4768@2|Bacteria,1UBBB@1239|Firmicutes,4IMQ8@91061|Bacilli,1ZKKT@1386|Bacillus 91061|Bacilli S protein containing a divergent version of the methyl-accepting chemotaxis-like domain - - - - - - - - - - - - DUF948 k141_19092_1 1345697.M493_07815 8.74e-75 232.0 COG0352@1|root,COG0352@2|Bacteria,1V3ZR@1239|Firmicutes,4HH1E@91061|Bacilli,1WFFP@129337|Geobacillus 91061|Bacilli H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) thiE GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 ko:K00788 ko00730,ko01100,map00730,map01100 M00127 R03223,R10712 RC00224,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU38290 TMP-TENI k141_11955_1 218284.CCDN010000001_gene650 1.72e-138 397.0 COG2255@1|root,COG2255@2|Bacteria,1TR47@1239|Firmicutes,4HBMW@91061|Bacilli,1ZC5A@1386|Bacillus 91061|Bacilli L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing ruvB - 3.6.4.12 ko:K03551 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvB_C,RuvB_N k141_14360_1 574376.BAMA_16745 1.63e-88 284.0 COG3973@1|root,COG3973@2|Bacteria,1TP39@1239|Firmicutes,4H9Y5@91061|Bacilli,1ZAWP@1386|Bacillus 91061|Bacilli L DNA helicase uvrD - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_19,UvrD-helicase,UvrD_C,UvrD_C_2 k141_3664_1 324602.Caur_2883 2.73e-70 220.0 COG1011@1|root,COG1011@2|Bacteria,2G7B3@200795|Chloroflexi,376JH@32061|Chloroflexia 32061|Chloroflexia S HAD-superfamily hydrolase, subfamily IA, variant 2 (HAD-like) - - 3.8.1.2 ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 - R05287 RC00697 ko00000,ko00001,ko01000 - - - HAD_2 k141_9587_1 315749.Bcer98_2713 1.1e-37 139.0 COG1175@1|root,COG1175@2|Bacteria,1TR2A@1239|Firmicutes,4HB8H@91061|Bacilli,1ZBHD@1386|Bacillus 91061|Bacilli P COG1175 ABC-type sugar transport systems, permease components malC GO:0003674,GO:0003824,GO:0005215,GO:0005363,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015154,GO:0015157,GO:0015399,GO:0015405,GO:0015422,GO:0015423,GO:0015766,GO:0015768,GO:0015772,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0032991,GO:0034219,GO:0042623,GO:0042626,GO:0043190,GO:0043211,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990060,GO:1990351 - ko:K15771 ko02010,map02010 M00491 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.16,3.A.1.1.2 - iYO844.BSU34150 BPD_transp_1 k141_9587_2 1231057.AMGD01000062_gene1005 2.43e-14 72.4 COG2182@1|root,COG2182@2|Bacteria,1TPU9@1239|Firmicutes,4HBHE@91061|Bacilli,26GA2@186818|Planococcaceae 91061|Bacilli G Bacterial extracellular solute-binding protein cycB - - ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 M00207,M00491,M00599 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.16,3.A.1.1.2,3.A.1.1.38 - - SBP_bac_8 k141_2487_1 1453501.JELR01000002_gene1535 2.94e-108 316.0 2DA4I@1|root,32TUN@2|Bacteria,1N0WK@1224|Proteobacteria,1S6HI@1236|Gammaproteobacteria,467DY@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_31005_1 935836.JAEL01000033_gene4086 4.41e-90 276.0 COG3493@1|root,COG3493@2|Bacteria,1TR97@1239|Firmicutes,4HBS8@91061|Bacilli,1ZC12@1386|Bacillus 91061|Bacilli C COG3493 Na citrate symporter mleP - - - - - - - - - - - 2HCT k141_23831_1 218284.CCDN010000004_gene3125 1.14e-218 623.0 COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,4HADT@91061|Bacilli,1ZCKV@1386|Bacillus 91061|Bacilli KT Sigma-54 interaction domain - - - - - - - - - - - - HTH_12,HTH_8,PAS,PAS_9,Sigma54_activat k141_17942_1 218284.CCDN010000002_gene2859 2.41e-164 468.0 2DB9X@1|root,2Z7ZS@2|Bacteria,1VS9F@1239|Firmicutes,4HTUJ@91061|Bacilli,1ZC1U@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3445) - - 1.14.13.238 ko:K22342 - - - - ko00000,ko01000 - - - DUF3445 k141_25021_1 935836.JAEL01000025_gene2341 2.76e-15 73.9 COG3396@1|root,COG3396@2|Bacteria,1TPWQ@1239|Firmicutes,4HCRX@91061|Bacilli,1ZB84@1386|Bacillus 91061|Bacilli Q Phenylacetic acid catabolic protein paaC - 1.14.13.149 ko:K02611 ko00360,ko01120,map00360,map01120 - R09838 RC02690 ko00000,ko00001,ko01000 - - - PaaA_PaaC k141_35874_2 1423321.AS29_18840 2.2e-13 67.0 2E6UJ@1|root,331E9@2|Bacteria,1VHQQ@1239|Firmicutes,4HPYC@91061|Bacilli,1ZK3H@1386|Bacillus 91061|Bacilli - - ybyB - - - - - - - - - - - - k141_13387_1 1294265.JCM21738_2533 1.22e-107 322.0 COG1004@1|root,COG1004@2|Bacteria,1TQFN@1239|Firmicutes,4HADP@91061|Bacilli,1ZAP3@1386|Bacillus 91061|Bacilli M Belongs to the UDP-glucose GDP-mannose dehydrogenase family - - 1.1.1.22 ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 M00014,M00129,M00361,M00362 R00286 RC00291 ko00000,ko00001,ko00002,ko01000 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N k141_21692_1 218284.CCDN010000002_gene2395 1.73e-66 215.0 2DBJR@1|root,2Z9N7@2|Bacteria,1TRSN@1239|Firmicutes,4HCDI@91061|Bacilli,1ZN92@1386|Bacillus 91061|Bacilli S Spore germination B3/ GerAC like, C-terminal - - - - - - - - - - - - Spore_GerAC k141_12221_1 574087.Acear_0895 4.21e-44 156.0 COG0540@1|root,COG0540@2|Bacteria,1TQ96@1239|Firmicutes,2496D@186801|Clostridia,3WAHT@53433|Halanaerobiales 186801|Clostridia F PFAM aspartate ornithine carbamoyltransferase carbamoyl-P binding domain pyrB - 2.1.3.2 ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N k141_12221_2 1487923.DP73_07320 6.43e-49 162.0 COG2065@1|root,COG2065@2|Bacteria,1V3GV@1239|Firmicutes,24FQD@186801|Clostridia,261GH@186807|Peptococcaceae 186801|Clostridia F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant pyrR - 2.4.2.9 ko:K02825 ko00240,ko01100,map00240,map01100 - R00966 RC00063 ko00000,ko00001,ko01000,ko03000 - - iHN637.CLJU_RS05275 Pribosyltran k141_4989_1 1249975.JQLP01000005_gene2366 1.24e-39 149.0 COG0280@1|root,COG0857@1|root,COG0280@2|Bacteria,COG0857@2|Bacteria,4NGX5@976|Bacteroidetes,1HYGN@117743|Flavobacteriia,2P5NG@244698|Gillisia 976|Bacteroidetes C DRTGG domain pta - 2.3.1.8 ko:K00625,ko:K13788 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00230,R00921 RC00004,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000 - - - AAA_26,DRTGG,PTA_PTB k141_9746_1 1379270.AUXF01000006_gene39 1.91e-13 75.1 COG1629@1|root,COG4771@2|Bacteria,1ZST4@142182|Gemmatimonadetes 142182|Gemmatimonadetes P CarboxypepD_reg-like domain - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - CarboxypepD_reg,Plug,TonB_dep_Rec k141_19260_1 1294265.JCM21738_3636 1.43e-180 513.0 COG4146@1|root,COG4146@2|Bacteria,1UHPR@1239|Firmicutes,4HDFI@91061|Bacilli,1ZDJB@1386|Bacillus 91061|Bacilli S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - ko:K03307 - - - - ko00000 2.A.21 - - SSF k141_3877_1 218284.CCDN010000005_gene3343 2.15e-127 372.0 COG3104@1|root,COG3104@2|Bacteria,1TP81@1239|Firmicutes,4HAF2@91061|Bacilli,1ZAVZ@1386|Bacillus 91061|Bacilli E amino acid peptide transporter - - - ko:K03305 - - - - ko00000 2.A.17 - - PTR2 k141_20399_1 1279017.AQYJ01000020_gene1266 7.19e-69 211.0 COG1610@1|root,COG1610@2|Bacteria,1RGZS@1224|Proteobacteria,1S61A@1236|Gammaproteobacteria,4678Q@72275|Alteromonadaceae 1236|Gammaproteobacteria S Yqey-like protein lporfX - - ko:K09117 - - - - ko00000 - - - YqeY k141_22867_1 218284.CCDN010000001_gene1751 6.7e-45 155.0 COG0626@1|root,COG0626@2|Bacteria,1TPC7@1239|Firmicutes,4HAFQ@91061|Bacilli,1ZAR9@1386|Bacillus 91061|Bacilli E cystathionine metC GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0016740,GO:0016765,GO:0016829,GO:0016846 4.4.1.8 ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU11880 Cys_Met_Meta_PP k141_22867_2 218284.CCDN010000001_gene1752 2.07e-71 224.0 COG0626@1|root,COG0626@2|Bacteria,1TPC7@1239|Firmicutes,4HAFQ@91061|Bacilli,1ZAR9@1386|Bacillus 91061|Bacilli E cystathionine metB GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0016740,GO:0016765,GO:0016829,GO:0016846 2.5.1.48 ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017 R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946 RC00020,RC00056,RC00069,RC00420,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000 - - - Cys_Met_Meta_PP k141_32270_2 218284.CCDN010000007_gene3867 1.39e-108 322.0 COG4972@1|root,COG4972@2|Bacteria,1TSTJ@1239|Firmicutes,4HD01@91061|Bacilli,1ZCYF@1386|Bacillus 91061|Bacilli NU Pilus assembly protein - - - ko:K18640 - - - - ko00000,ko04812 - - - StbA k141_26547_1 1121091.AUMP01000003_gene2551 3.46e-83 252.0 2C9JF@1|root,32RPD@2|Bacteria,1VC16@1239|Firmicutes,4HK64@91061|Bacilli 91061|Bacilli S ERF superfamily - - - - - - - - - - - - ERF k141_27543_1 223926.28805061 5.5e-271 743.0 COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,1RNCW@1236|Gammaproteobacteria,1XSRR@135623|Vibrionales 135623|Vibrionales S HI0933-like protein yhiN - - ko:K07007 - - - - ko00000 - - - HI0933_like k141_8592_2 218284.CCDN010000010_gene4364 3.05e-56 175.0 COG0089@1|root,COG0089@2|Bacteria,1VA4W@1239|Firmicutes,4HKCV@91061|Bacilli,1ZH09@1386|Bacillus 91061|Bacilli J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome rplW GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02892 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L23 k141_10939_1 1196031.ALEG01000065_gene81 1.49e-152 438.0 COG4303@1|root,COG4303@2|Bacteria,1TP15@1239|Firmicutes,4HE2S@91061|Bacilli,1ZDBE@1386|Bacillus 91061|Bacilli E Ethanolamine ammonia lyase large subunit (EutB) - - 4.3.1.7 ko:K03735 ko00564,ko01100,map00564,map01100 - R00749 RC00370 ko00000,ko00001,ko01000 - - - EutB k141_3878_2 1267580.AF6_2248 6.17e-26 108.0 COG0665@1|root,COG0665@2|Bacteria,1VTRW@1239|Firmicutes,4HD2K@91061|Bacilli,21WMP@150247|Anoxybacillus 91061|Bacilli E FAD dependent oxidoreductase thiO GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016491,GO:0016638,GO:0016641,GO:0019752,GO:0022607,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043799,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0048037,GO:0050660,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0097159,GO:1901265,GO:1901363,GO:1901564 1.4.3.19 ko:K03153 ko00730,ko01100,map00730,map01100 - R07463 RC01788 ko00000,ko00001,ko01000 - - - DAO k141_22868_1 1294265.JCM21738_2231 1.88e-57 191.0 COG3303@1|root,COG3303@2|Bacteria,1TPPW@1239|Firmicutes,4I6NR@91061|Bacilli,1ZEPE@1386|Bacillus 91061|Bacilli P Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process nrfA - 1.7.2.2 ko:K03385 ko00910,ko01120,ko05132,map00910,map01120,map05132 M00530 R05712 RC00176 ko00000,ko00001,ko00002,ko01000 - - - Cytochrom_C552 k141_22868_2 1294265.JCM21738_2230 6.66e-58 179.0 COG3005@1|root,COG3005@2|Bacteria,1VEVM@1239|Firmicutes,4IN2R@91061|Bacilli,1ZDFR@1386|Bacillus 91061|Bacilli C COG3005 Nitrate TMAO reductases, membrane-bound tetraheme cytochrome c subunit nrfH - - ko:K15876 ko00910,ko01120,map00910,map01120 M00530 R05712 RC00176 ko00000,ko00001,ko00002 - - - Cytochrom_NNT k141_21693_1 1294265.JCM21738_2904 8.8e-72 228.0 COG0114@1|root,COG0114@2|Bacteria,1UHPH@1239|Firmicutes,4HA6P@91061|Bacilli,1ZS23@1386|Bacillus 91061|Bacilli C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate fumC GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 M00009,M00011,M00173,M00376 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS09430 FumaraseC_C,Lyase_1 k141_26548_1 1380387.JADM01000019_gene3319 2.05e-50 169.0 COG1309@1|root,COG1309@2|Bacteria,1RDIM@1224|Proteobacteria,1S4DI@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator - - - - - - - - - - - - TetR_N k141_33524_1 1279017.AQYJ01000028_gene2401 2.6e-239 692.0 COG1523@1|root,COG1523@2|Bacteria,1MU19@1224|Proteobacteria,1RP6F@1236|Gammaproteobacteria,465SK@72275|Alteromonadaceae 1236|Gammaproteobacteria G Belongs to the glycosyl hydrolase 13 family pulA - 3.2.1.41 ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 - R02111 - ko00000,ko00001,ko01000 - CBM48,GH13 - Alpha-amylase,CBM_48,DUF3372,PUD k141_33524_2 1298865.H978DRAFT_2270 4.7e-123 365.0 COG3386@1|root,COG3386@2|Bacteria,1NIN4@1224|Proteobacteria,1RZ4N@1236|Gammaproteobacteria 1236|Gammaproteobacteria G PFAM Major royal jelly protein - - - - - - - - - - - - MRJP k141_25239_1 1294265.JCM21738_5450 1.21e-102 297.0 COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,4HIIF@91061|Bacilli,1ZGBU@1386|Bacillus 91061|Bacilli S ATPase or kinase ydiB GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 - ko:K06925 - - - - ko00000,ko03016 - - - TsaE k141_25239_2 1131730.BAVI_01730 4e-71 220.0 COG1214@1|root,COG1214@2|Bacteria,1V4YX@1239|Firmicutes,4HHD7@91061|Bacilli,1ZC43@1386|Bacillus 91061|Bacilli O COG1214 Inactive homolog of metal-dependent proteases yeaZ GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 ko:K01409,ko:K14742 - - R10648 RC00070,RC00416 ko00000,ko01000,ko03016 - - - Peptidase_M22 k141_16937_1 218284.CCDN010000001_gene1172 2.35e-93 276.0 COG1755@1|root,COG1755@2|Bacteria,1V6IY@1239|Firmicutes,4HIFN@91061|Bacilli,1ZGT0@1386|Bacillus 91061|Bacilli S protein conserved in bacteria ypbQ - - ko:K16168 - - - - ko00000,ko01008 - - - ICMT k141_6326_1 223926.28805126 4.23e-77 236.0 COG1218@1|root,COG1218@2|Bacteria,1N0GY@1224|Proteobacteria,1RP5A@1236|Gammaproteobacteria,1XUIT@135623|Vibrionales 135623|Vibrionales P COG1218 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase cysQ - 3.1.3.7 ko:K01082 ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130 - R00188,R00508 RC00078 ko00000,ko00001,ko01000,ko03016 - - - Inositol_P k141_6326_2 1219076.N646_2334 7.01e-127 361.0 COG0494@1|root,COG0494@2|Bacteria,1RCX7@1224|Proteobacteria,1S3ZE@1236|Gammaproteobacteria,1XSE9@135623|Vibrionales 135623|Vibrionales L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes nudE - - ko:K08312 ko00230,map00230 - R01054 RC00002 ko00000,ko00001,ko01000 - - - NUDIX k141_6326_3 674977.VMC_13990 2.36e-135 383.0 COG0316@1|root,COG0694@1|root,COG0316@2|Bacteria,COG0694@2|Bacteria,1MU8Y@1224|Proteobacteria,1RN7J@1236|Gammaproteobacteria,1XSGB@135623|Vibrionales 135623|Vibrionales C Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins nfuA - - ko:K07400 - - - - ko00000 - - - Fe-S_biosyn,NifU k141_6326_4 223926.28805129 3.16e-125 362.0 COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,1S64Q@1236|Gammaproteobacteria,1XT5I@135623|Vibrionales 135623|Vibrionales S Phosphoribosyl transferase domain gntX - - - - - - - - - - - Pribosyltran k141_1412_1 218284.CCDN010000001_gene989 1.74e-67 222.0 COG1884@1|root,COG1884@2|Bacteria,1TSVA@1239|Firmicutes,4HDE1@91061|Bacilli,1ZAVR@1386|Bacillus 91061|Bacilli I COG1884 Methylmalonyl-CoA mutase, N-terminal domain subunit mutA - 5.4.99.2 ko:K01847 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00373,M00376,M00741 R00833 RC00395 ko00000,ko00001,ko00002,ko01000 - - - MM_CoA_mutase k141_26549_1 42565.FP66_00705 4.63e-135 394.0 COG1012@1|root,COG1012@2|Bacteria,1MUHV@1224|Proteobacteria,1RNFN@1236|Gammaproteobacteria,1XIE7@135619|Oceanospirillales 135619|Oceanospirillales C methylmalonate-semialdehyde dehydrogenase - - 1.2.1.18,1.2.1.27 ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 M00013 R00705,R00706,R00922,R00935 RC00004,RC02723,RC02817 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_4990_1 661478.OP10G_4657 1.45e-18 87.8 COG2461@1|root,COG4191@1|root,COG2461@2|Bacteria,COG4191@2|Bacteria 2|Bacteria T Histidine kinase - - 2.1.1.80,3.1.1.61 ko:K13924 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 - - - DUF2249,GAF_2,HATPase_c,HATPase_c_2,HWE_HK,HisKA,HisKA_2,PAS,PAS_3,PAS_4,PAS_9,Response_reg k141_4990_2 1340434.AXVA01000007_gene5141 2.3e-09 55.1 2BFBE@1|root,3294H@2|Bacteria,1UBGB@1239|Firmicutes,4IMV2@91061|Bacilli,1ZKWF@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - Flp_Fap k141_29929_1 218284.CCDN010000002_gene2668 2.76e-114 341.0 COG0659@1|root,COG0659@2|Bacteria,1TPI4@1239|Firmicutes,4H9V4@91061|Bacilli,1ZCKC@1386|Bacillus 91061|Bacilli P COG0659 Sulfate permease and related transporters (MFS superfamily) ybaR - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - STAS,Sulfate_transp k141_34732_1 1453501.JELR01000001_gene2929 7.42e-56 195.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,466AN@72275|Alteromonadaceae 1236|Gammaproteobacteria V AcrB/AcrD/AcrF family bepG - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran k141_34732_2 1453501.JELR01000001_gene2928 1.47e-106 311.0 COG0494@1|root,COG0494@2|Bacteria,1RD2C@1224|Proteobacteria,1SA4Q@1236|Gammaproteobacteria,467P1@72275|Alteromonadaceae 1236|Gammaproteobacteria L NUDIX domain - - - - - - - - - - - - NUDIX k141_34732_3 1453501.JELR01000001_gene2927 0.0 953.0 COG5265@1|root,COG5265@2|Bacteria,1NSKS@1224|Proteobacteria,1T1W9@1236|Gammaproteobacteria,463YF@72275|Alteromonadaceae 1236|Gammaproteobacteria V COG5265 ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components atmA - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran k141_34732_4 1279017.AQYJ01000021_gene2838 7.05e-317 874.0 COG0457@1|root,COG0457@2|Bacteria,1Q3YA@1224|Proteobacteria,1RN2D@1236|Gammaproteobacteria,46595@72275|Alteromonadaceae 1236|Gammaproteobacteria S Peptidase family M49 - - - - - - - - - - - - Peptidase_M49 k141_34732_6 1279017.AQYJ01000021_gene2846 3.39e-247 691.0 COG0122@1|root,COG2169@1|root,COG0122@2|Bacteria,COG2169@2|Bacteria,1QTXM@1224|Proteobacteria,1RNQB@1236|Gammaproteobacteria,464XA@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG2169 Adenosine deaminase ada - 3.2.2.21 ko:K01247,ko:K13529 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03000,ko03400 - - - Ada_Zn_binding,AlkA_N,HTH_18,HhH-GPD k141_34732_7 1279017.AQYJ01000021_gene2847 4.46e-66 206.0 COG0350@1|root,COG0350@2|Bacteria,1N2YQ@1224|Proteobacteria,1S68H@1236|Gammaproteobacteria,467W5@72275|Alteromonadaceae 1236|Gammaproteobacteria L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated ogt - 2.1.1.63 ko:K00567 - - - - ko00000,ko01000,ko03400 - - - DNA_binding_1,Methyltransf_1N k141_34732_8 1453501.JELR01000001_gene2923 7.66e-76 231.0 COG0663@1|root,COG0663@2|Bacteria,1RD76@1224|Proteobacteria,1S3WC@1236|Gammaproteobacteria,466YX@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily yrdA - - - - - - - - - - - Hexapep,Hexapep_2 k141_7423_2 1177181.T9A_02002 7.16e-63 198.0 2BY4C@1|root,32XUX@2|Bacteria,1N0C0@1224|Proteobacteria,1SAJV@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_4991_1 323850.Shew_2305 1.23e-22 100.0 COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,1RMB0@1236|Gammaproteobacteria,2QAVQ@267890|Shewanellaceae 1236|Gammaproteobacteria H Belongs to the folylpolyglutamate synthase family folC GO:0003674,GO:0003824,GO:0004326,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006761,GO:0006807,GO:0008150,GO:0008152,GO:0008841,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046452,GO:0046483,GO:0046900,GO:0046901,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_1997,iSDY_1059.SDY_2514 Mur_ligase_C,Mur_ligase_M k141_18155_1 518766.Rmar_2588 1.15e-87 269.0 COG0543@1|root,COG0543@2|Bacteria 2|Bacteria C 2 iron, 2 sulfur cluster binding asrB - - ko:K02823 ko00240,ko01100,map00240,map01100 - - - ko00000,ko00001 - - - DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1 k141_18155_2 1279017.AQYJ01000025_gene475 8.93e-146 416.0 COG1941@1|root,COG1941@2|Bacteria,1NS0E@1224|Proteobacteria,1RW0G@1236|Gammaproteobacteria,466Y9@72275|Alteromonadaceae 1236|Gammaproteobacteria C NADH ubiquinone oxidoreductase, 20 Kd subunit hoxY - - - - - - - - - - - Oxidored_q6 k141_18155_3 1279017.AQYJ01000025_gene474 6.71e-230 643.0 COG3259@1|root,COG3259@2|Bacteria,1QUQ7@1224|Proteobacteria,1T20U@1236|Gammaproteobacteria,4654F@72275|Alteromonadaceae 1236|Gammaproteobacteria C Nickel-dependent hydrogenase hoxH - - - - - - - - - - - NiFeSe_Hases k141_18155_5 1279017.AQYJ01000025_gene472 6.01e-34 119.0 2DCC8@1|root,2ZDND@2|Bacteria 2|Bacteria S Hydrogenase/urease nickel incorporation, metallochaperone, hypA - - - - - - - - - - - - HypA k141_18155_6 1279017.AQYJ01000025_gene471 3.49e-241 698.0 COG0068@1|root,COG0068@2|Bacteria,1MVP8@1224|Proteobacteria,1RP08@1236|Gammaproteobacteria,4642Z@72275|Alteromonadaceae 1236|Gammaproteobacteria O Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide hypF GO:0003674,GO:0003824,GO:0005488,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0010467,GO:0016740,GO:0016741,GO:0016743,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046872,GO:0046914,GO:0046944,GO:0051604,GO:0071704,GO:1901564 - ko:K04656 - - - - ko00000 - - - Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF k141_18155_7 518766.Rmar_2594 2.81e-25 96.7 COG0298@1|root,COG0298@2|Bacteria,4NX9T@976|Bacteroidetes 976|Bacteroidetes O PFAM hydrogenase expression formation protein (HUPF HYPC) - - - ko:K04653 - - - - ko00000 - - - HupF_HypC k141_18155_8 1279017.AQYJ01000025_gene469 1.8e-174 497.0 COG0409@1|root,COG0409@2|Bacteria,1MU1F@1224|Proteobacteria,1RRTQ@1236|Gammaproteobacteria,466NH@72275|Alteromonadaceae 1236|Gammaproteobacteria O Belongs to the HypD family hypD - - ko:K04654 - - - - ko00000 - - - HypD k141_18155_9 1279017.AQYJ01000025_gene468 1.57e-147 425.0 COG0309@1|root,COG0309@2|Bacteria,1MVCC@1224|Proteobacteria,1RQBE@1236|Gammaproteobacteria,466ND@72275|Alteromonadaceae 1236|Gammaproteobacteria O AIR synthase related protein, N-terminal domain hypE GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0018193,GO:0018198,GO:0018249,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046892,GO:0051604,GO:0071704,GO:1901564 - ko:K04655 - - - - ko00000 - - - AIRS,AIRS_C k141_18155_10 760568.Desku_3192 6.79e-07 52.8 COG2149@1|root,COG2149@2|Bacteria,1VJG8@1239|Firmicutes,24SZR@186801|Clostridia,266DQ@186807|Peptococcaceae 186801|Clostridia S Domain of unknown function (DUF202) - - - ko:K00389 - - - - ko00000 - - - DUF202 k141_18155_11 1030157.AFMP01000004_gene2086 6.61e-29 112.0 COG2062@1|root,COG2062@2|Bacteria,1N0FX@1224|Proteobacteria,2UBYD@28211|Alphaproteobacteria,2K4JB@204457|Sphingomonadales 204457|Sphingomonadales T phosphohistidine phosphatase sixA - - ko:K08296 - - - - ko00000,ko01000 - - - His_Phos_1 k141_33525_1 1042377.AFPJ01000024_gene767 5.18e-111 333.0 COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,1RQQV@1236|Gammaproteobacteria,46448@72275|Alteromonadaceae 1236|Gammaproteobacteria MU COG1538 Outer membrane protein tolC - - ko:K12340 ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133 M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko02044 1.B.17,2.A.6.2 - - OEP k141_27544_1 1294265.JCM21738_1952 1.08e-44 146.0 COG1918@1|root,COG1918@2|Bacteria,1VGV9@1239|Firmicutes,4HPQB@91061|Bacilli,1ZJ0N@1386|Bacillus 91061|Bacilli P COG1918 Fe2 transport system protein A - - - ko:K04758 - - - - ko00000,ko02000 - - - FeoA k141_14520_29 1268239.PALB_23110 4.94e-15 77.0 2AZFE@1|root,31RPB@2|Bacteria,1QP6J@1224|Proteobacteria,1SITZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_14520_32 345073.VC395_A0209 3.41e-120 348.0 COG3617@1|root,COG3617@2|Bacteria,1N0VX@1224|Proteobacteria,1SACX@1236|Gammaproteobacteria 1236|Gammaproteobacteria K BRO family, N-terminal domain - - - - - - - - - - - - Bro-N,P22_AR_C k141_32291_2 1294265.JCM21738_2233 1.33e-115 340.0 COG0477@1|root,COG2814@2|Bacteria,1TPJ6@1239|Firmicutes,4HAGJ@91061|Bacilli,1ZBPE@1386|Bacillus 91061|Bacilli EGP Major facilitator superfamily yttB - - - - - - - - - - - MFS_1 k141_25261_1 1294265.JCM21738_4887 4.72e-41 135.0 2EIS2@1|root,33CHE@2|Bacteria,1VM34@1239|Firmicutes,4HR6Z@91061|Bacilli,1ZK09@1386|Bacillus 91061|Bacilli S Inhibitor of sigma-G Gin csfB - - - - - - - - - - - Gin k141_25261_2 1294265.JCM21738_4885 7.77e-250 693.0 COG1982@1|root,COG1982@2|Bacteria,1TNZ9@1239|Firmicutes,4HBGC@91061|Bacilli,1ZBKS@1386|Bacillus 91061|Bacilli E Orn Lys Arg decarboxylase yaaO - - - - - - - - - - - OKR_DC_1,OKR_DC_1_C k141_25261_3 1294265.JCM21738_4884 1.2e-15 73.2 COG0125@1|root,COG0125@2|Bacteria,1V1HE@1239|Firmicutes,4HGWR@91061|Bacilli,1ZBSZ@1386|Bacillus 91061|Bacilli F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis tmk GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 ko:K00943 ko00240,ko01100,map00240,map01100 M00053 R02094,R02098 RC00002 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS02535 Thymidylate_kin k141_3905_2 218284.CCDN010000001_gene1890 3e-47 152.0 COG2740@1|root,COG2740@2|Bacteria,1VEJS@1239|Firmicutes,4HKBY@91061|Bacilli,1ZHSV@1386|Bacillus 91061|Bacilli K nucleic-acid-binding protein implicated in transcription termination ylxR - - ko:K07742 - - - - ko00000 - - - DUF448 k141_3905_3 1034347.CAHJ01000010_gene2033 6.37e-45 147.0 COG1358@1|root,COG1358@2|Bacteria,1VEYG@1239|Firmicutes,4HNY7@91061|Bacilli,1ZI1N@1386|Bacillus 91061|Bacilli J ribosomal protein ylxQ - - - - - - - - - - - Ribosomal_L7Ae k141_3905_4 997296.PB1_00900 4.74e-16 80.1 COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,4HA8S@91061|Bacilli,1ZBWA@1386|Bacillus 91061|Bacilli J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,IF-2,IF2_N k141_26592_1 218284.CCDN010000001_gene1602 9e-102 300.0 COG0515@1|root,COG0515@2|Bacteria,1UTWM@1239|Firmicutes,4H9YQ@91061|Bacilli,1ZR6X@1386|Bacillus 91061|Bacilli KLT serine threonine protein kinase - - - - - - - - - - - - - k141_37072_2 218284.CCDN010000001_gene1254 9.02e-53 172.0 COG1968@1|root,COG1968@2|Bacteria,1TPFA@1239|Firmicutes,4HCE7@91061|Bacilli,1ZC3Z@1386|Bacillus 91061|Bacilli V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin uppP - 3.6.1.27 ko:K06153 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - BacA k141_18184_1 218284.CCDN010000001_gene1531 1.46e-71 232.0 COG0578@1|root,COG0578@2|Bacteria,1TQJN@1239|Firmicutes,4HAG8@91061|Bacilli,1ZCGN@1386|Bacillus 91061|Bacilli C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family glpD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.1.3.21,1.1.5.3 ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 - R00846,R00848 RC00029 ko00000,ko00001,ko01000 - - - DAO,DAO_C k141_33549_1 322710.Avin_31060 2.95e-131 400.0 COG5635@1|root,COG5635@2|Bacteria,1NU2G@1224|Proteobacteria,1SKZB@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Nacht domain - - - - - - - - - - - - - k141_19290_1 1453501.JELR01000002_gene210 2e-88 277.0 COG5001@1|root,COG5001@2|Bacteria,1NQIF@1224|Proteobacteria,1T3FC@1236|Gammaproteobacteria,46CJ0@72275|Alteromonadaceae 1236|Gammaproteobacteria T diguanylate cyclase - - 2.7.7.65 ko:K20956,ko:K21023 ko02025,ko05111,map02025,map05111 - - - ko00000,ko00001,ko01000 - - - CHASE,EAL,GAF_2,GGDEF,PAS_4,PAS_9 k141_15759_1 1382359.JIAL01000001_gene723 1.14e-104 320.0 COG1012@1|root,COG1012@2|Bacteria,3Y37W@57723|Acidobacteria,2JHJP@204432|Acidobacteriia 204432|Acidobacteriia C Delta-1-pyrroline-5-carboxylate dehydrogenase - - 1.2.1.88 ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 - R00245,R00707,R00708,R04444,R04445,R05051 RC00080,RC00216,RC00242,RC00255 ko00000,ko00001,ko01000 - - - Aldedh k141_15759_2 316274.Haur_0796 3.52e-06 50.1 COG0477@1|root,COG2814@2|Bacteria,2G6DM@200795|Chloroflexi,375GE@32061|Chloroflexia 32061|Chloroflexia EGP PFAM major facilitator superfamily MFS_1 - - - ko:K08151 - M00668 - - ko00000,ko00002,ko01504,ko02000 2.A.1.2.38,2.A.1.2.39,2.A.1.2.4,2.A.1.2.41,2.A.1.2.68,2.A.1.2.75 - - MFS_1,Sugar_tr k141_5020_1 218284.CCDN010000006_gene3621 2.48e-218 632.0 COG0745@1|root,COG5000@1|root,COG5002@1|root,COG0745@2|Bacteria,COG5000@2|Bacteria,COG5002@2|Bacteria,1U7NI@1239|Firmicutes,4HA3E@91061|Bacilli,1ZCFX@1386|Bacillus 91061|Bacilli T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - GAF,GAF_3,HAMP,HATPase_c,HisKA,Response_reg k141_35900_2 1235279.C772_02660 8.57e-34 121.0 COG3189@1|root,COG3189@2|Bacteria,1VABH@1239|Firmicutes,4HKI2@91061|Bacilli,26HKK@186818|Planococcaceae 91061|Bacilli S Protein of unknown function, DUF488 yeaO - - - - - - - - - - - DUF488 k141_26593_1 218284.CCDN010000005_gene3400 2.7e-99 301.0 COG0737@1|root,COG0737@2|Bacteria,1TQCW@1239|Firmicutes,4HAUC@91061|Bacilli,1ZCJ8@1386|Bacillus 91061|Bacilli F Belongs to the 5'-nucleotidase family yunD - 3.1.3.5 ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - 5_nucleotid_C,Metallophos k141_1425_1 1116375.VEJY3_23006 5.59e-27 107.0 COG2072@1|root,COG2072@2|Bacteria,1MU71@1224|Proteobacteria,1RP8X@1236|Gammaproteobacteria 1236|Gammaproteobacteria P flavoprotein involved in K transport - - - - - - - - - - - - FMO-like,NAD_binding_8,Pyr_redox_3 k141_1425_2 1116375.VEJY3_23011 2.89e-213 593.0 COG2207@1|root,COG2207@2|Bacteria,1MX23@1224|Proteobacteria,1RXXK@1236|Gammaproteobacteria,1XVU6@135623|Vibrionales 135623|Vibrionales K AraC-type DNA-binding domain-containing - - - - - - - - - - - - Arabinose_bd,HTH_18 k141_1425_3 1217718.ALOU01000007_gene1257 5.48e-272 766.0 28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria 1224|Proteobacteria S Protein of unknown function (DUF3604) - - - - - - - - - - - - DUF3604 k141_1425_4 985054.JQEZ01000001_gene1947 1.08e-41 151.0 COG0760@1|root,COG0760@2|Bacteria,1R4ZR@1224|Proteobacteria,2U874@28211|Alphaproteobacteria,4NDDY@97050|Ruegeria 28211|Alphaproteobacteria O PPIC-type PPIASE domain - - 5.2.1.8 ko:K03769 - - - - ko00000,ko01000,ko03110 - - - Rotamase_2 k141_16971_1 435908.IDSA_08120 3.32e-131 397.0 COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria,2QGM7@267893|Idiomarinaceae 1236|Gammaproteobacteria O PA domain - - - - - - - - - - - - PA,PKD,Peptidase_S8 k141_28870_1 1347368.HG964406_gene6483 8.55e-26 110.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1TR2N@1239|Firmicutes,4H9RR@91061|Bacilli,1ZB2Q@1386|Bacillus 91061|Bacilli EU peptidase yuxL - 3.4.19.1 ko:K01303 - - - - ko00000,ko01000,ko01002 - - - PD40,Peptidase_S9 k141_12256_1 218284.CCDN010000001_gene1384 1.59e-246 679.0 COG0263@1|root,COG0263@2|Bacteria,1TPG6@1239|Firmicutes,4HA9B@91061|Bacilli,1ZAPU@1386|Bacillus 91061|Bacilli E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate proB GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 M00015 R00239 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,PUA k141_3906_1 315730.BcerKBAB4_2936 7.78e-82 268.0 COG0369@1|root,COG2124@1|root,COG0369@2|Bacteria,COG2124@2|Bacteria,1TS1E@1239|Firmicutes,4HCWS@91061|Bacilli,1ZQAP@1386|Bacillus 91061|Bacilli C Belongs to the cytochrome P450 family cypD GO:0000166,GO:0003674,GO:0003824,GO:0003958,GO:0004497,GO:0005488,GO:0005504,GO:0005506,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008289,GO:0009987,GO:0010181,GO:0016491,GO:0016651,GO:0016653,GO:0016705,GO:0016712,GO:0019395,GO:0019752,GO:0020037,GO:0030258,GO:0031406,GO:0032553,GO:0032787,GO:0033293,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363 1.14.14.1,1.6.2.4 ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 - R03629,R04121,R05259 RC00046,RC01311 ko00000,ko00001,ko00199,ko01000 - - - FAD_binding_1,Flavodoxin_1,NAD_binding_1,p450 k141_22908_1 1279017.AQYJ01000023_gene3089 1.91e-247 693.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,4643Q@72275|Alteromonadaceae 1236|Gammaproteobacteria JKL DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation deaD GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003725,GO:0003727,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006417,GO:0006725,GO:0006807,GO:0006950,GO:0006996,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009266,GO:0009314,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009987,GO:0010468,GO:0010501,GO:0010556,GO:0010557,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019439,GO:0022607,GO:0022613,GO:0022618,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031330,GO:0032268,GO:0032270,GO:0033554,GO:0033592,GO:0034248,GO:0034250,GO:0034622,GO:0034641,GO:0034655,GO:0042254,GO:0042255,GO:0042273,GO:0042623,GO:0043170,GO:0043487,GO:0043488,GO:0043489,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045934,GO:0046483,GO:0046700,GO:0048255,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0061013,GO:0065003,GO:0065007,GO:0065008,GO:0070035,GO:0070417,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097617,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902369,GO:1902373,GO:1903311,GO:1903312,GO:2000112 3.6.4.13 ko:K05592 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,DEADboxA,DbpA,Helicase_C k141_22908_2 1453501.JELR01000002_gene221 1.02e-82 249.0 COG3038@1|root,COG3038@2|Bacteria,1RBP8@1224|Proteobacteria,1S563@1236|Gammaproteobacteria,468V5@72275|Alteromonadaceae 1236|Gammaproteobacteria C Prokaryotic cytochrome b561 cybB - - ko:K12262 - - - - ko00000 - - - Ni_hydr_CYTB k141_22908_3 1279017.AQYJ01000023_gene3093 0.0 944.0 COG1228@1|root,COG1228@2|Bacteria,1MY4V@1224|Proteobacteria,1RZRK@1236|Gammaproteobacteria,46606@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Amidohydrolase family - - - - - - - - - - - - Amidohydro_1 k141_29932_2 1279017.AQYJ01000025_gene756 1.17e-240 711.0 COG2902@1|root,COG2902@2|Bacteria,1MXNV@1224|Proteobacteria,1RQVZ@1236|Gammaproteobacteria,464UW@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG2902 NAD-specific glutamate dehydrogenase gdhB - 1.4.1.2 ko:K15371 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 - R00243 RC00006,RC02799 ko00000,ko00001,ko01000 - - - Bac_GDH,GDH_N k141_5021_1 218284.CCDN010000001_gene34 6.85e-143 417.0 COG1461@1|root,COG1461@2|Bacteria,1TQMX@1239|Firmicutes,4HBSE@91061|Bacilli,1ZBRP@1386|Bacillus 91061|Bacilli S kinase related to dihydroxyacetone kinase yloV - - ko:K07030 - - - - ko00000 - - - Dak1_2,Dak2 k141_13655_1 1384049.CD29_00315 1.34e-23 102.0 2DM5R@1|root,31TR8@2|Bacteria,1V9HS@1239|Firmicutes,4HJF9@91061|Bacilli 91061|Bacilli - - lig1 - - - - - - - - - - - - k141_13655_2 218284.CCDN010000001_gene10 7.51e-41 136.0 COG2257@1|root,COG2257@2|Bacteria,1VF4R@1239|Firmicutes,4HPCF@91061|Bacilli,1ZIW6@1386|Bacillus 91061|Bacilli S homolog of the cytoplasmic domain of flagellar protein FhlB ylqH - - ko:K04061 - - - - ko00000,ko02044 - - - Bac_export_2 k141_7532_1 796606.BMMGA3_03395 4.9e-71 224.0 COG1090@1|root,COG1090@2|Bacteria,1TRCE@1239|Firmicutes,4HBRT@91061|Bacilli,1ZBKW@1386|Bacillus 91061|Bacilli S nucleoside-diphosphate sugar epimerase yfhF - - ko:K07071 - - - - ko00000 - - - DUF1731,Epimerase k141_12492_1 1340434.AXVA01000020_gene1433 1.56e-47 166.0 COG0591@1|root,COG0591@2|Bacteria,1V0QU@1239|Firmicutes,4HASR@91061|Bacilli,1ZE7C@1386|Bacillus 91061|Bacilli E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - - - - - - - - - - SSF k141_12492_2 1200792.AKYF01000019_gene4614 2.03e-30 114.0 COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1URF2@1239|Firmicutes,4HFVG@91061|Bacilli,26WHM@186822|Paenibacillaceae 91061|Bacilli T helix_turn_helix, arabinose operon control protein - - - ko:K07720 ko02020,map02020 M00519 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_18,HTH_AraC,Response_reg k141_18349_1 218284.CCDN010000001_gene94 3.99e-94 288.0 COG4365@1|root,COG4365@2|Bacteria,1TQ2P@1239|Firmicutes,4HA2Z@91061|Bacilli,1ZBMV@1386|Bacillus 91061|Bacilli S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH bshC - - ko:K22136 - - - - ko00000 - - - BshC k141_23129_2 1294265.JCM21738_4839 3.34e-35 126.0 28KFQ@1|root,2ZA1R@2|Bacteria,1V063@1239|Firmicutes,4HFDF@91061|Bacilli,1ZCCB@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - DUF3794 k141_11182_1 491915.Aflv_0284 1.38e-51 177.0 COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,1TSQZ@1239|Firmicutes,4HCYZ@91061|Bacilli 91061|Bacilli P Zn-dependent gloB - 3.1.2.6 ko:K01069 ko00620,map00620 - R01736 RC00004,RC00137 ko00000,ko00001,ko01000 - - - Lactamase_B,Rhodanese k141_1579_1 1116375.VEJY3_12540 1.17e-13 69.7 COG2207@1|root,COG2207@2|Bacteria,1N7DZ@1224|Proteobacteria,1SYZE@1236|Gammaproteobacteria,1XWDS@135623|Vibrionales 135623|Vibrionales K COG2207 AraC-type DNA-binding domain-containing proteins - - - - - - - - - - - - HTH_18 k141_36009_1 1123008.KB905698_gene3399 2.9e-44 160.0 COG0745@1|root,COG0745@2|Bacteria,4PM6N@976|Bacteroidetes,2G0CY@200643|Bacteroidia,2323Q@171551|Porphyromonadaceae 976|Bacteroidetes T PglZ domain - - - - - - - - - - - - PglZ,Response_reg k141_33775_1 1042377.AFPJ01000007_gene1830 1.89e-49 176.0 COG3297@1|root,COG3297@2|Bacteria 2|Bacteria U Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins xcpY - - ko:K02461 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - GspL_C,T2SSL k141_27643_1 218284.CCDN010000001_gene276 1.83e-123 364.0 COG1757@1|root,COG1757@2|Bacteria,1TQ3B@1239|Firmicutes,4HA18@91061|Bacilli,1ZBQN@1386|Bacillus 91061|Bacilli C Na H antiporter nhaC_2 - - ko:K03315 - - - - ko00000,ko02000 2.A.35 - - Na_H_antiporter k141_34899_2 1121935.AQXX01000113_gene1411 3.2e-209 593.0 COG1488@1|root,COG1488@2|Bacteria,1MWA2@1224|Proteobacteria,1RPPA@1236|Gammaproteobacteria,1XN1B@135619|Oceanospirillales 135619|Oceanospirillales H Nicotinate phosphoribosyltransferase (NAPRTase) family - - 2.4.2.12 ko:K03462 ko00760,ko01100,ko04621,map00760,map01100,map04621 - R01271 RC00033 ko00000,ko00001,ko01000 - - - NAPRTase k141_34899_4 1279017.AQYJ01000027_gene1705 6.01e-179 504.0 COG0484@1|root,COG0484@2|Bacteria,1MUZ4@1224|Proteobacteria,1RP09@1236|Gammaproteobacteria,4668N@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG2214 DnaJ-class molecular chaperone cbpA GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0097159,GO:1901363 - ko:K05516 - - - - ko00000,ko03036,ko03110 - - - DnaJ,DnaJ_C k141_34899_5 1279017.AQYJ01000027_gene1704 3.92e-45 148.0 COG0789@1|root,COG0789@2|Bacteria,1N9MT@1224|Proteobacteria,1SE7J@1236|Gammaproteobacteria,46CFA@72275|Alteromonadaceae 1236|Gammaproteobacteria K MerR HTH family regulatory protein cbpM - - ko:K18997 - - - - ko00000,ko03036 - - - MerR_2 k141_34899_7 1042377.AFPJ01000036_gene1167 1.63e-68 224.0 COG2979@1|root,COG2979@2|Bacteria,1R95E@1224|Proteobacteria,1S2WZ@1236|Gammaproteobacteria,467M2@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF533) yebE - - - - - - - - - - - DUF533 k141_34899_10 1172186.KB911472_gene5369 4.47e-17 81.6 COG3751@1|root,COG3751@2|Bacteria,2HN62@201174|Actinobacteria 201174|Actinobacteria O 2OG-Fe(II) oxygenase superfamily - - - - - - - - - - - - 2OG-FeII_Oxy_3 k141_6465_1 1122137.AQXF01000007_gene3599 7.73e-183 523.0 COG0665@1|root,COG0665@2|Bacteria,1MU40@1224|Proteobacteria,2TTKE@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Tryptophan halogenase - - - - - - - - - - - - Trp_halogenase k141_6465_2 425104.Ssed_1209 7.07e-08 54.7 COG0665@1|root,COG0665@2|Bacteria,1MU40@1224|Proteobacteria,1RMJY@1236|Gammaproteobacteria,2QAJQ@267890|Shewanellaceae 1236|Gammaproteobacteria E PFAM tryptophan halogenase prnA - 1.14.19.9 ko:K14266 ko00404,ko01130,map00404,map01130 M00789,M00790 R09570 RC00949 ko00000,ko00001,ko00002,ko01000 - - - Trp_halogenase k141_20604_1 223926.28809409 1.81e-06 48.5 COG0778@1|root,COG0778@2|Bacteria,1N95W@1224|Proteobacteria,1RSDH@1236|Gammaproteobacteria,1XVNT@135623|Vibrionales 135623|Vibrionales C Nitroreductase family nfnB - 1.5.1.34 ko:K10679 ko00633,ko01120,map00633,map01120 - R08014,R08017,R08042 RC00250 ko00000,ko00001,ko01000 - - - Nitroreductase k141_20604_2 1280001.BAOA01000022_gene543 9.59e-132 380.0 COG1028@1|root,COG1028@2|Bacteria,1P9R4@1224|Proteobacteria,1RYF6@1236|Gammaproteobacteria,1XT36@135623|Vibrionales 135623|Vibrionales IQ KR domain - - - - - - - - - - - - adh_short k141_20604_3 1348635.BBJY01000006_gene510 2.05e-175 494.0 COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,1SYHI@1236|Gammaproteobacteria,1Y2N3@135623|Vibrionales 135623|Vibrionales K Bacterial regulatory helix-turn-helix protein, lysR family - - - - - - - - - - - - HTH_1,LysR_substrate k141_20604_4 1280001.BAOA01000070_gene2854 2.94e-175 496.0 COG1902@1|root,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,1RMII@1236|Gammaproteobacteria,1XSK1@135623|Vibrionales 1236|Gammaproteobacteria C NADH:flavin oxidoreductase / NADH oxidase family - - 1.6.99.1 ko:K00354 - - R00282 RC00001 ko00000,ko01000 - - - Oxidored_FMN k141_20604_5 675806.VII_000433 3.71e-22 94.4 COG5361@1|root,COG5361@2|Bacteria,1R799@1224|Proteobacteria,1RS9T@1236|Gammaproteobacteria,1XW9B@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF1214) - - - - - - - - - - - - DUF1214,DUF1254 k141_20604_6 675806.VII_000433 7.08e-53 178.0 COG5361@1|root,COG5361@2|Bacteria,1R799@1224|Proteobacteria,1RS9T@1236|Gammaproteobacteria,1XW9B@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF1214) - - - - - - - - - - - - DUF1214,DUF1254 k141_576_1 1453501.JELR01000001_gene3188 1.09e-32 114.0 COG2331@1|root,COG2331@2|Bacteria,1N6Q9@1224|Proteobacteria,1SCJS@1236|Gammaproteobacteria,468ET@72275|Alteromonadaceae 1236|Gammaproteobacteria S Putative regulatory protein - - - - - - - - - - - - Zn-ribbon_8 k141_576_2 1279017.AQYJ01000022_gene2662 0.0 1077.0 COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,1RNMI@1236|Gammaproteobacteria,46435@72275|Alteromonadaceae 1236|Gammaproteobacteria J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) aspS GO:0003674,GO:0003824,GO:0004812,GO:0004815,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006422,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - iSFV_1184.SFV_1868 GAD,tRNA-synt_2,tRNA_anti-codon k141_7533_1 1294265.JCM21738_2077 6.01e-51 163.0 COG4940@1|root,COG4940@2|Bacteria,1VKRP@1239|Firmicutes,4HR6S@91061|Bacilli,1ZIZV@1386|Bacillus 91061|Bacilli U COG4940 Competence protein ComGF comGF - - ko:K02248 - M00429 - - ko00000,ko00002,ko02044 - - - ComGF,N_methyl k141_7533_3 935836.JAEL01000057_gene1230 1.42e-14 70.9 COG0703@1|root,COG0703@2|Bacteria,1VA6Z@1239|Firmicutes,4HKD6@91061|Bacilli,1ZHX4@1386|Bacillus 91061|Bacilli F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate aroK GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - SKI k141_18351_1 1294265.JCM21738_2767 1.58e-62 193.0 2C26N@1|root,32K4G@2|Bacteria,1VAMA@1239|Firmicutes,4HJZD@91061|Bacilli,1ZHTT@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_18351_2 1294265.JCM21738_2766 4.89e-86 253.0 COG1586@1|root,COG1586@2|Bacteria,1V3U2@1239|Firmicutes,4HH1F@91061|Bacilli,1ZFPA@1386|Bacillus 91061|Bacilli E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine speH - 4.1.1.50 ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 M00034,M00133 R00178 RC00299 ko00000,ko00001,ko00002,ko01000 - - - AdoMet_dc k141_28961_1 1219076.N646_1260 5.56e-152 432.0 COG0252@1|root,COG0252@2|Bacteria,1MWIR@1224|Proteobacteria,1RMUB@1236|Gammaproteobacteria,1XU6G@135623|Vibrionales 135623|Vibrionales EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D ansA - 3.5.1.1 ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 - R00485 RC00010,RC02798 ko00000,ko00001,ko01000 - - - Asparaginase k141_24174_1 1116375.VEJY3_05450 1.35e-157 446.0 COG0500@1|root,COG2226@2|Bacteria,1PA5F@1224|Proteobacteria,1RY7A@1236|Gammaproteobacteria,1XTUZ@135623|Vibrionales 135623|Vibrionales H Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway bioC - 2.1.1.197 ko:K02169 ko00780,ko01100,map00780,map01100 M00572 R09543 RC00003,RC00460 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_11 k141_24174_2 223926.28806103 6.12e-30 111.0 COG0132@1|root,COG0132@2|Bacteria,1RDRK@1224|Proteobacteria,1RSHS@1236|Gammaproteobacteria,1XSF9@135623|Vibrionales 135623|Vibrionales H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring bioD GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.3 ko:K01935 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R03182 RC00868 ko00000,ko00001,ko00002,ko01000 - - - AAA_26 k141_23131_2 1042377.AFPJ01000055_gene987 4.26e-91 267.0 COG0200@1|root,COG0200@2|Bacteria,1RDC8@1224|Proteobacteria,1S3P6@1236|Gammaproteobacteria,4670D@72275|Alteromonadaceae 1236|Gammaproteobacteria J Binds to the 23S rRNA rplO GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02876 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27A k141_20605_2 582515.KR51_00018200 0.00082 42.7 2FD7D@1|root,3459D@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k141_33776_2 1000565.METUNv1_03199 2.16e-06 49.7 COG2032@1|root,COG2032@2|Bacteria,1RGV4@1224|Proteobacteria,2WFV1@28216|Betaproteobacteria,2KXHE@206389|Rhodocyclales 206389|Rhodocyclales P Superoxide dismutase - - 1.15.1.1 ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 - - - ko00000,ko00001,ko01000 - - - Sod_Cu k141_11183_1 1042377.AFPJ01000007_gene1903 1.02e-277 761.0 COG1805@1|root,COG1805@2|Bacteria,1QTUU@1224|Proteobacteria,1RMGH@1236|Gammaproteobacteria,46504@72275|Alteromonadaceae 1236|Gammaproteobacteria C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol nqrB GO:0000166,GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008144,GO:0008150,GO:0008152,GO:0010181,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0019842,GO:0030001,GO:0030964,GO:0032553,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0044425,GO:0044464,GO:0048037,GO:0050136,GO:0050662,GO:0051179,GO:0051234,GO:0055114,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:1901265,GO:1901363,GO:1902444,GO:1902494 1.6.5.8 ko:K00347 - - - - ko00000,ko01000 - - - NQR2_RnfD_RnfE k141_37223_1 1453501.JELR01000001_gene1811 2.62e-65 214.0 COG4325@1|root,COG4325@2|Bacteria,1MXTM@1224|Proteobacteria,1RNYZ@1236|Gammaproteobacteria,466NZ@72275|Alteromonadaceae 1236|Gammaproteobacteria S Predicted membrane protein (DUF2254) - - - - - - - - - - - - DUF2254 k141_37223_2 1279017.AQYJ01000024_gene1176 1.35e-100 293.0 COG2193@1|root,COG2193@2|Bacteria,1RCW7@1224|Proteobacteria,1S45S@1236|Gammaproteobacteria,466EC@72275|Alteromonadaceae 1236|Gammaproteobacteria P Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex bfr GO:0003674,GO:0003824,GO:0004322,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016722,GO:0016724,GO:0019725,GO:0020037,GO:0030003,GO:0042592,GO:0042802,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046906,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0097159,GO:0097577,GO:0098771,GO:1901363 1.16.3.1 ko:K03594 ko00860,map00860 - R00078 RC02758 ko00000,ko00001,ko01000 - - - Ferritin k141_577_1 218284.CCDN010000006_gene3593 1.57e-71 218.0 COG1845@1|root,COG1845@2|Bacteria,1TQJ1@1239|Firmicutes,4HCWH@91061|Bacilli,1ZDEX@1386|Bacillus 91061|Bacilli C quinol oxidase, subunit qoxC GO:0003674,GO:0003824,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016679,GO:0016682,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.10.3.12 ko:K02828 ko00190,ko01100,map00190,map01100 M00416 R09492 RC00819 ko00000,ko00001,ko00002,ko01000 - - - COX3 k141_12494_1 1432050.IE4771_CH00926 1.13e-06 55.5 COG4907@1|root,COG4907@2|Bacteria,1MXPY@1224|Proteobacteria,2TUBP@28211|Alphaproteobacteria,4B77J@82115|Rhizobiaceae 28211|Alphaproteobacteria S Predicted membrane protein (DUF2207) - - - - - - - - - - - - DUF2207 k141_10005_2 666686.B1NLA3E_19430 1.6e-28 104.0 COG4897@1|root,COG4897@2|Bacteria,1VMTY@1239|Firmicutes,4HQMX@91061|Bacilli,1ZITV@1386|Bacillus 91061|Bacilli S protein conserved in bacteria csbA - - - - - - - - - - - DUF2198 k141_5231_1 1453501.JELR01000002_gene772 2.61e-243 696.0 COG0834@1|root,COG4623@1|root,COG0834@2|Bacteria,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,1RM8W@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella - GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - ko:K18691 - - - - ko00000,ko01000,ko01011 - - - SBP_bac_3,SLT k141_21840_1 1453501.JELR01000002_gene1259 2.25e-273 763.0 COG1506@1|root,COG1506@2|Bacteria,1MUJ3@1224|Proteobacteria,1RPAW@1236|Gammaproteobacteria,46468@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases - - - - - - - - - - - - Peptidase_S9 k141_21840_2 1453501.JELR01000002_gene1258 2.21e-67 226.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RS1Q@1236|Gammaproteobacteria,469PS@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_27644_1 218284.CCDN010000005_gene3342 1.27e-49 164.0 COG1295@1|root,COG1295@2|Bacteria,1U7HM@1239|Firmicutes,4H9MJ@91061|Bacilli,1ZCX5@1386|Bacillus 91061|Bacilli S Virulence factor BrkB yihY - - ko:K07058 - - - - ko00000 - - - Virul_fac_BrkB k141_27644_2 218284.CCDN010000005_gene3343 2.39e-40 144.0 COG3104@1|root,COG3104@2|Bacteria,1TP81@1239|Firmicutes,4HAF2@91061|Bacilli,1ZAVZ@1386|Bacillus 91061|Bacilli E amino acid peptide transporter - - - ko:K03305 - - - - ko00000 2.A.17 - - PTR2 k141_11184_2 1499684.CCNP01000019_gene2171 2.67e-54 177.0 COG2323@1|root,COG2323@2|Bacteria,1V1AI@1239|Firmicutes,24EAT@186801|Clostridia,36H29@31979|Clostridiaceae 186801|Clostridia S Protein of unknown function (DUF421) - - - - - - - - - - - - DUF421 k141_7534_1 218284.CCDN010000005_gene3166 9.67e-90 275.0 COG0420@1|root,COG0420@2|Bacteria,1TWMI@1239|Firmicutes,4HCA0@91061|Bacilli,1ZC5G@1386|Bacillus 91061|Bacilli L DNA repair exonuclease yhaO - - ko:K03547 - - - - ko00000,ko03400 - - - Metallophos,Metallophos_2 k141_1581_1 1453501.JELR01000002_gene342 2.46e-95 310.0 COG1361@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4932@2|Bacteria,1R5G4@1224|Proteobacteria,1SEWA@1236|Gammaproteobacteria,469S7@72275|Alteromonadaceae 1236|Gammaproteobacteria M Domain of unknown function DUF11 - - - - - - - - - - - - DUF11,SdrD_B k141_19465_1 1116375.VEJY3_16216 0.0 896.0 COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,1RZ7N@1236|Gammaproteobacteria,1XUEW@135623|Vibrionales 135623|Vibrionales S Putative modulator of DNA gyrase - - - ko:K03568 - - - - ko00000,ko01002 - - - PmbA_TldD k141_19465_2 1116375.VEJY3_16221 3.98e-295 808.0 COG0312@1|root,COG0312@2|Bacteria,1MUVW@1224|Proteobacteria,1RZ2J@1236|Gammaproteobacteria,1XW2A@135623|Vibrionales 135623|Vibrionales S Putative modulator of DNA gyrase - - - ko:K03592 - - - - ko00000,ko01002 - - - PmbA_TldD k141_19465_3 223926.28808278 2.43e-135 384.0 COG1901@1|root,COG1901@2|Bacteria,1R7NM@1224|Proteobacteria,1RSHK@1236|Gammaproteobacteria,1XTCJ@135623|Vibrionales 135623|Vibrionales J pseudouridine methyltransferase - - 2.1.1.257 ko:K16317 - - - - ko00000,ko01000,ko03016 - - - Methyltrn_RNA_2 k141_19465_4 1116375.VEJY3_16231 8.93e-103 299.0 29C1Y@1|root,2ZZ0F@2|Bacteria,1REVX@1224|Proteobacteria,1S4BA@1236|Gammaproteobacteria,1XX5Y@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF3087) VVA0269 - - - - - - - - - - - DUF3087 k141_578_1 218284.CCDN010000001_gene1273 1.46e-74 242.0 COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,1TSAC@1239|Firmicutes,4HAJG@91061|Bacilli,1ZB2G@1386|Bacillus 91061|Bacilli L ATP-dependent DNA ligase ligD - 6.5.1.1 ko:K01971 ko03450,map03450 - R00381 RC00005 ko00000,ko00001,ko01000,ko03400 - - - DNA_ligase_A_M k141_36010_1 1403313.AXBR01000013_gene1349 4.75e-56 182.0 COG0514@1|root,COG0514@2|Bacteria,1UNCK@1239|Firmicutes,4IUA0@91061|Bacilli,1ZSFN@1386|Bacillus 91061|Bacilli L Nuclease-related domain - - - - - - - - - - - - NERD k141_5232_1 1340493.JNIF01000003_gene2230 2.5e-61 199.0 COG0535@1|root,COG0535@2|Bacteria,3Y3TY@57723|Acidobacteria 57723|Acidobacteria S 4Fe-4S single cluster domain - - - - - - - - - - - - Fer4_12,Fer4_14,Radical_SAM k141_12495_1 218284.CCDN010000001_gene788 9.91e-168 472.0 COG0226@1|root,COG0226@2|Bacteria,1TQ5X@1239|Firmicutes,4HBEB@91061|Bacilli,1ZB22@1386|Bacillus 91061|Bacilli P Phosphate pstS GO:0003674,GO:0005488,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015698,GO:0042301,GO:0043167,GO:0043168,GO:0051179,GO:0051234 - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - PBP_like_2 k141_33778_1 42565.FP66_06330 3.55e-137 406.0 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,1RQUR@1236|Gammaproteobacteria,1XIN6@135619|Oceanospirillales 135619|Oceanospirillales F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen - - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - LAGLIDADG_3,Ribonuc_red_lgC,Ribonuc_red_lgN k141_34900_1 1116375.VEJY3_10095 5.08e-185 525.0 COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,1RQR7@1236|Gammaproteobacteria,1XUQ4@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria VP1916 - - ko:K21470 - - - - ko00000,ko01002,ko01011 - - - PG_binding_1,YkuD k141_34900_2 1116375.VEJY3_10090 1.48e-114 330.0 COG3108@1|root,COG3108@2|Bacteria,1MWW2@1224|Proteobacteria,1RS5K@1236|Gammaproteobacteria,1XX77@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria ycbK - - - - - - - - - - - Peptidase_M15_2 k141_13658_2 1453501.JELR01000001_gene2036 2.58e-114 361.0 COG1014@1|root,COG4231@1|root,COG1014@2|Bacteria,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,1RSEQ@1236|Gammaproteobacteria,465RF@72275|Alteromonadaceae 1236|Gammaproteobacteria C Pyruvate ferredoxin/flavodoxin oxidoreductase - - 1.2.7.8 ko:K04090 - - - - br01601,ko00000,ko01000 - - - POR,TPP_enzyme_C k141_23132_3 218284.CCDN010000006_gene3654 1.02e-51 165.0 2DZIG@1|root,32VBI@2|Bacteria,1VFCW@1239|Firmicutes,4HMIY@91061|Bacilli,1ZIVR@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF4870) yvlA - - - - - - - - - - - DUF4870 k141_17070_2 218284.CCDN010000001_gene1442 3.27e-124 355.0 COG2197@1|root,COG2197@2|Bacteria,1TVTF@1239|Firmicutes,4HAJW@91061|Bacilli,1ZC1V@1386|Bacillus 91061|Bacilli T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain desR - - ko:K07693 ko02020,map02020 M00479 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg k141_34936_1 1294265.JCM21738_3492 2.18e-96 282.0 COG0041@1|root,COG0041@2|Bacteria,1V1MV@1239|Firmicutes,4HFR7@91061|Bacilli,1ZFRE@1386|Bacillus 91061|Bacilli F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) purE - 5.4.99.18 ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07405 RC01947 ko00000,ko00001,ko00002,ko01000 - - - AIRC k141_34936_2 1294265.JCM21738_3493 2e-72 228.0 COG0026@1|root,COG0026@2|Bacteria,1TQCD@1239|Firmicutes,4H9M5@91061|Bacilli,1ZB8P@1386|Bacillus 91061|Bacilli F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) purK GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 6.3.4.18 ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07404 RC01927 ko00000,ko00001,ko00002,ko01000 - - - 2-Hacid_dh_C,ATP-grasp k141_25493_1 218284.CCDN010000010_gene4381 1.32e-30 108.0 COG0690@1|root,COG0690@2|Bacteria,1VK48@1239|Firmicutes,4HR1W@91061|Bacilli,1ZIY2@1386|Bacillus 91061|Bacilli U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation secE - - ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecE k141_25493_2 665952.HMPREF1015_02883 6.09e-124 356.0 COG1595@1|root,COG1595@2|Bacteria,1TP55@1239|Firmicutes,4HAHR@91061|Bacilli,1ZBEV@1386|Bacillus 91061|Bacilli K Belongs to the sigma-70 factor family sigH - - ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 - - - ko00000,ko00001,ko03000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_25493_3 218284.CCDN010000010_gene4383 1.29e-104 303.0 COG3688@1|root,COG3688@2|Bacteria,1V9XR@1239|Firmicutes,4HFW4@91061|Bacilli,1ZCMG@1386|Bacillus 91061|Bacilli S RNA-binding protein containing a PIN domain yacP - - ko:K06962 - - - - ko00000 - - - NYN_YacP k141_25493_4 218284.CCDN010000010_gene4384 8.89e-164 459.0 COG0566@1|root,COG0566@2|Bacteria,1TP9G@1239|Firmicutes,4HBBI@91061|Bacilli,1ZAXC@1386|Bacillus 91061|Bacilli J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family trmH GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 ko:K03218 - - - - ko00000,ko01000,ko03009 - - - SpoU_methylase,SpoU_sub_bind k141_25493_5 218284.CCDN010000010_gene4385 1.08e-77 233.0 COG1939@1|root,COG1939@2|Bacteria,1VA5V@1239|Firmicutes,4HIM3@91061|Bacilli,1ZH0Z@1386|Bacillus 91061|Bacilli J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc) mrnC GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 - ko:K11145 - - - - ko00000,ko01000,ko03009 - - - Ribonuclease_3 k141_11214_1 218284.CCDN010000003_gene2997 1.54e-78 235.0 COG1098@1|root,COG1098@2|Bacteria,1V6FE@1239|Firmicutes,4HIKM@91061|Bacilli,1ZG7S@1386|Bacillus 91061|Bacilli J RNA binding protein (contains ribosomal protein S1 domain) yabR - - ko:K07571 - - - - ko00000 - - - S1 k141_11214_2 218284.CCDN010000003_gene2998 2.61e-74 228.0 COG2318@1|root,COG2318@2|Bacteria,1VAGC@1239|Firmicutes,4HMA9@91061|Bacilli,1ZFRM@1386|Bacillus 91061|Bacilli S DinB superfamily - - - - - - - - - - - - DinB_2 k141_4103_1 1116375.VEJY3_18416 1.55e-64 206.0 COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,1RPTT@1236|Gammaproteobacteria,1XY63@135623|Vibrionales 135623|Vibrionales U Belongs to the binding-protein-dependent transport system permease family - - - ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 k141_4103_2 223926.28809519 4.46e-182 510.0 COG0559@1|root,COG0559@2|Bacteria,1MU25@1224|Proteobacteria,1RNDV@1236|Gammaproteobacteria,1Y2IF@135623|Vibrionales 135623|Vibrionales P Belongs to the binding-protein-dependent transport system permease family - - - ko:K01997 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 k141_13684_1 218284.CCDN010000001_gene1825 6.14e-111 329.0 COG2855@1|root,COG2855@2|Bacteria,1TQYA@1239|Firmicutes,4HCCP@91061|Bacilli,1ZATM@1386|Bacillus 91061|Bacilli S Conserved hypothetical protein 698 - - - - - - - - - - - - Cons_hypoth698 k141_8849_1 1121938.AUDY01000008_gene970 1.58e-195 553.0 COG0591@1|root,COG0591@2|Bacteria,1TRYH@1239|Firmicutes,4HE2W@91061|Bacilli,3NECT@45667|Halobacillus 91061|Bacilli E Sodium:solute symporter family - - - - - - - - - - - - SSF k141_23168_1 672.VV93_v1c34580 2.88e-91 275.0 COG1840@1|root,COG1840@2|Bacteria,1MXZ8@1224|Proteobacteria,1RPPC@1236|Gammaproteobacteria,1XSDQ@135623|Vibrionales 135623|Vibrionales P ABC-type Fe3 transport system, periplasmic component - - - ko:K02012 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - SBP_bac_6 k141_23168_2 223926.28808376 3.21e-247 681.0 COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,1RMTS@1236|Gammaproteobacteria,1XSM6@135623|Vibrionales 135623|Vibrionales P Belongs to the ABC transporter superfamily - - 3.6.3.30 ko:K02010,ko:K02052 ko02010,ko02024,map02010,map02024 M00190,M00193 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.10,3.A.1.11 - - ABC_tran,TOBE_2 k141_23168_3 223926.28808377 0.0 1041.0 COG1178@1|root,COG1178@2|Bacteria,1MXZZ@1224|Proteobacteria,1RY3W@1236|Gammaproteobacteria,1XTGS@135623|Vibrionales 135623|Vibrionales P ABC-type Fe3 transport system, permease component - - - ko:K02011 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - BPD_transp_1 k141_23168_4 1116375.VEJY3_16586 2.8e-163 457.0 COG2188@1|root,COG2188@2|Bacteria,1R4PN@1224|Proteobacteria,1RQ87@1236|Gammaproteobacteria,1XT3H@135623|Vibrionales 135623|Vibrionales K COG2188 Transcriptional regulators phnR - - - - - - - - - - - GntR,UTRA k141_27664_2 1123270.ATUR01000002_gene2333 6.06e-16 77.0 COG1062@1|root,COG1062@2|Bacteria,1MUK4@1224|Proteobacteria,2TT67@28211|Alphaproteobacteria,2K04T@204457|Sphingomonadales 204457|Sphingomonadales C Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily - - 1.1.1.1,1.1.1.284 ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 - R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N k141_25706_4 1116375.VEJY3_19151 5.27e-26 103.0 COG0583@1|root,COG0583@2|Bacteria,1NZBS@1224|Proteobacteria,1SQGQ@1236|Gammaproteobacteria,1XVE0@135623|Vibrionales 135623|Vibrionales K COG0583 Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_13884_2 1042377.AFPJ01000051_gene79 1.36e-85 282.0 COG3188@1|root,COG3188@2|Bacteria,1MWV6@1224|Proteobacteria,1SZYH@1236|Gammaproteobacteria,46AZV@72275|Alteromonadaceae 1236|Gammaproteobacteria NU Outer membrane usher protein - - - - - - - - - - - - Usher k141_23297_1 266117.Rxyl_3069 1.96e-11 63.9 COG2259@1|root,COG2259@2|Bacteria 2|Bacteria S methylamine metabolic process - - 1.8.5.2 ko:K15977,ko:K16937 ko00920,ko01120,map00920,map01120 - R07177 - ko00000,ko00001,ko01000 3.D.4.9 - - DoxX k141_2928_1 218284.CCDN010000001_gene1495 2.14e-99 301.0 COG2233@1|root,COG2233@2|Bacteria,1TQ0A@1239|Firmicutes,4HA6X@91061|Bacilli,1ZD5W@1386|Bacillus 91061|Bacilli F Xanthine uracil ywdJ GO:0003674,GO:0005215,GO:0005345,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006863,GO:0008150,GO:0015205,GO:0015851,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0042906,GO:0042907,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072530,GO:1904823 - - - - - - - - - - Xan_ur_permease k141_4217_1 218284.CCDN010000006_gene3741 2.7e-105 319.0 COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,4HA1G@91061|Bacilli,1ZASC@1386|Bacillus 91061|Bacilli G COG0366 Glycosidases dexB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.2.1.70 ko:K01215 - - - - ko00000,ko01000 - - - Alpha-amylase,DUF3459,Malt_amylase_C k141_27774_1 223926.28808838 1.3e-141 402.0 COG2030@1|root,COG2030@2|Bacteria,1RAHS@1224|Proteobacteria,1T0EH@1236|Gammaproteobacteria,1XTU1@135623|Vibrionales 135623|Vibrionales I COG2030 Acyl dehydratase - - - - - - - - - - - - MaoC_dehydratas k141_27774_2 1116375.VEJY3_21211 1.9e-172 484.0 COG0226@1|root,COG0226@2|Bacteria,1MW2Z@1224|Proteobacteria,1S5B9@1236|Gammaproteobacteria,1XTQY@135623|Vibrionales 135623|Vibrionales P COG0226 ABC-type phosphate transport system, periplasmic component - - - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - PBP_like,PBP_like_2 k141_27774_3 1116375.VEJY3_21206 5.92e-76 227.0 2AWCE@1|root,31N87@2|Bacteria,1QJZK@1224|Proteobacteria,1TI21@1236|Gammaproteobacteria,1XY73@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF3024) - - - - - - - - - - - - DUF3024 k141_27774_4 1116375.VEJY3_21201 0.0 1267.0 COG4776@1|root,COG4776@2|Bacteria,1P563@1224|Proteobacteria,1RP5G@1236|Gammaproteobacteria,1XSNX@135623|Vibrionales 135623|Vibrionales J Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction rnb GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0008859,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360,GO:1901361,GO:1901575 3.1.13.1 ko:K01147 - - - - ko00000,ko01000,ko03016 - - - OB_RNB,RNB,S1 k141_27774_5 1116375.VEJY3_21496 2.85e-242 666.0 COG1064@1|root,COG1064@2|Bacteria,1MUTT@1224|Proteobacteria,1RPQC@1236|Gammaproteobacteria,1XVAU@135623|Vibrionales 135623|Vibrionales C COG1064 Zn-dependent alcohol dehydrogenases - - 1.1.1.1 ko:K13953,ko:K13979 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N k141_27774_6 1348635.BBJY01000010_gene1412 0.0 1036.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RRW1@1236|Gammaproteobacteria,1XVII@135623|Vibrionales 1236|Gammaproteobacteria T signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - - - - - - - - - - EAL,GGDEF,HAMP,dCache_1 k141_27774_7 1219076.N646_4553 0.0 1001.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1XUDK@135623|Vibrionales 135623|Vibrionales JKL DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation deaD - 3.6.4.13 ko:K05592 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,DbpA,Helicase_C k141_5481_1 1294265.JCM21738_1876 2.42e-104 312.0 COG0477@1|root,COG2814@2|Bacteria,1TQHD@1239|Firmicutes,4HBCZ@91061|Bacilli,1ZDDG@1386|Bacillus 91061|Bacilli EGP COG0477 Permeases of the major facilitator superfamily - - - - - - - - - - - - MFS_1,Sugar_tr k141_30179_1 1170562.Cal6303_0514 5.56e-28 115.0 COG0305@1|root,COG1372@1|root,COG0305@2|Bacteria,COG1372@2|Bacteria,1G0R8@1117|Cyanobacteria,1HJAT@1161|Nostocales 1117|Cyanobacteria L Participates in initiation and elongation during chromosome replication dnaB GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C,Intein_splicing,LAGLIDADG_3 k141_30179_2 1178540.BA70_06675 8.33e-11 58.2 2DI2G@1|root,301TN@2|Bacteria,1U8VM@1239|Firmicutes,4IIU2@91061|Bacilli,1ZPAU@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_1726_1 1131730.BAVI_18577 1.07e-52 171.0 2E0IB@1|root,305WE@2|Bacteria,1TYT5@1239|Firmicutes,4IKU0@91061|Bacilli,1ZHK3@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_29089_2 1453501.JELR01000002_gene395 1.8e-154 442.0 COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,1RMC5@1236|Gammaproteobacteria,4653C@72275|Alteromonadaceae 1236|Gammaproteobacteria V COG1131 ABC-type multidrug transport system, ATPase component - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_24357_1 1349767.GJA_1011 4.2e-05 45.4 COG0304@1|root,COG0304@2|Bacteria,1MV30@1224|Proteobacteria,2VI0P@28216|Betaproteobacteria,478FK@75682|Oxalobacteraceae 28216|Betaproteobacteria IQ Beta-ketoacyl synthase, C-terminal domain - GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 ko:K09458,ko:K14660 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt k141_24357_2 224324.aq_1717a 1.63e-28 104.0 COG0236@1|root,COG0236@2|Bacteria,2G491@200783|Aquificae 200783|Aquificae IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis acpP GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - ko:K02078 - - - - ko00000,ko00001 - - - PP-binding k141_24357_3 716544.wcw_1187 1.29e-06 49.3 COG1028@1|root,COG1028@2|Bacteria,2JFE8@204428|Chlamydiae 204428|Chlamydiae IQ Catalyzes the NADPH-dependent reduction of beta- ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis fabG - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 k141_18557_2 1123053.AUDG01000019_gene2522 4.31e-10 66.2 COG0427@1|root,COG1670@1|root,COG0427@2|Bacteria,COG1670@2|Bacteria,1N643@1224|Proteobacteria,1T1M3@1236|Gammaproteobacteria,1X2S1@135613|Chromatiales 135613|Chromatiales CJ Acetyl-CoA hydrolase/transferase N-terminal domain - - - - - - - - - - - - AcetylCoA_hyd_C,AcetylCoA_hydro,Acetyltransf_3 k141_13917_2 42565.FP66_12390 1.84e-11 63.2 COG1064@1|root,COG1064@2|Bacteria,1MUTT@1224|Proteobacteria,1RPQC@1236|Gammaproteobacteria 1236|Gammaproteobacteria S alcohol dehydrogenase adhA - 1.1.1.1 ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N k141_35154_1 218284.CCDN010000006_gene3748 1.34e-118 342.0 COG2188@1|root,COG2188@2|Bacteria,1TVMZ@1239|Firmicutes,4H9TD@91061|Bacilli,1ZF1V@1386|Bacillus 91061|Bacilli K UTRA ybgA - - ko:K03710 - - - - ko00000,ko03000 - - - GntR,UTRA k141_9015_1 880073.Calab_0924 6.7e-20 94.0 COG1629@1|root,COG4771@2|Bacteria,2NP6Z@2323|unclassified Bacteria 2|Bacteria P COGs COG1629 Outer membrane receptor protein mostly Fe transport - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec k141_27015_2 1453501.JELR01000002_gene1082 9.2e-24 100.0 COG0790@1|root,COG0790@2|Bacteria,1N4EV@1224|Proteobacteria,1SZKW@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Gram-negative bacterial TonB protein C-terminal - - - - - - - - - - - - Sel1,TonB_C k141_33949_1 379066.GAU_1580 1.25e-29 117.0 COG4591@1|root,COG4591@2|Bacteria,1ZT1N@142182|Gemmatimonadetes 142182|Gemmatimonadetes M MacB-like periplasmic core domain - - - ko:K09808 ko02010,map02010 M00255 - - ko00000,ko00001,ko00002,ko02000 3.A.1.125 - - FtsX,MacB_PCD k141_33949_2 653733.Selin_1056 4.05e-08 54.7 COG4591@1|root,COG4591@2|Bacteria 2|Bacteria M lipoprotein localization to outer membrane lolC GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008104,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0034613,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051641,GO:0070727,GO:0071944,GO:0072657,GO:0089705,GO:0098796,GO:0098797,GO:1990778 - ko:K02004,ko:K09808 ko02010,map02010 M00255,M00258 - - ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.125 - - FtsX,MacB_PCD k141_23340_1 1294265.JCM21738_2662 1.86e-84 257.0 COG2267@1|root,COG2267@2|Bacteria,1TSC4@1239|Firmicutes,4HBYX@91061|Bacilli,1ZEAA@1386|Bacillus 91061|Bacilli I hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - - - - - - - - - - Abhydrolase_1,Hydrolase_4 k141_2934_3 1453501.JELR01000001_gene2172 1.52e-160 465.0 COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,1RNIY@1236|Gammaproteobacteria,4659T@72275|Alteromonadaceae 1236|Gammaproteobacteria E Aminotransferase class-V - - - - - - - - - - - - Aminotran_5 k141_13918_1 1382305.AZUC01000063_gene3290 5.81e-31 113.0 COG0494@1|root,COG0494@2|Bacteria,1V4B2@1239|Firmicutes,4HGZZ@91061|Bacilli,26FKH@186818|Planococcaceae 91061|Bacilli L NUDIX domain - - - - - - - - - - - - NUDIX k141_18590_1 1279017.AQYJ01000029_gene3708 7.01e-115 343.0 COG0155@1|root,COG0155@2|Bacteria,1MVVB@1224|Proteobacteria,1RMFH@1236|Gammaproteobacteria,465NM@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG0155 Sulfite reductase, beta subunit (hemoprotein) cysI - 1.8.1.2 ko:K00381 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00176 R00858 RC00065 ko00000,ko00001,ko00002,ko01000 - - - NIR_SIR,NIR_SIR_ferr k141_10298_1 218284.CCDN010000007_gene3817 4.24e-77 244.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,1ZBV0@1386|Bacillus 91061|Bacilli V ABC transporter ywjA - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran k141_10298_2 218284.CCDN010000007_gene3816 5.61e-144 416.0 COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,4H9Y8@91061|Bacilli,1ZBUR@1386|Bacillus 91061|Bacilli L Participates in initiation and elongation during chromosome replication dnaB GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k141_23341_1 582744.Msip34_0048 3.85e-05 47.4 COG0631@1|root,COG0631@2|Bacteria,1MVE7@1224|Proteobacteria,2VIAV@28216|Betaproteobacteria,2KM5H@206350|Nitrosomonadales 206350|Nitrosomonadales T SMART protein phosphatase 2C domain protein - - 3.1.3.16 ko:K20074 - - - - ko00000,ko01000,ko01009 - - - PP2C_2 k141_23341_2 194867.ALBQ01000002_gene914 1.3e-68 213.0 COG0689@1|root,COG0689@2|Bacteria,1MVFZ@1224|Proteobacteria,2TRMC@28211|Alphaproteobacteria,2K0PW@204457|Sphingomonadales 204457|Sphingomonadales J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates rph - 2.7.7.56 ko:K00989 - - - - ko00000,ko01000,ko03016 - - - RNase_PH,RNase_PH_C k141_775_1 1279017.AQYJ01000029_gene3403 3.59e-17 82.0 COG4235@1|root,COG4235@2|Bacteria,1MY4J@1224|Proteobacteria,1S358@1236|Gammaproteobacteria,466S6@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG4235 Cytochrome c biogenesis factor cycH - - ko:K02200 - - - - ko00000 - - - TPR_16,TPR_2 k141_775_2 1279017.AQYJ01000029_gene3402 1.05e-70 219.0 COG3088@1|root,COG3088@2|Bacteria,1MZZ5@1224|Proteobacteria,1S9DV@1236|Gammaproteobacteria,467TB@72275|Alteromonadaceae 1236|Gammaproteobacteria P subunit of a heme lyase ccmH GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015035,GO:0015036,GO:0016020,GO:0016043,GO:0016491,GO:0016667,GO:0017004,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0055114,GO:0065003,GO:0071840,GO:0071944,GO:0098552,GO:0098567 - ko:K02200,ko:K04017 - - - - ko00000 - - - CcmH k141_775_3 298386.PBPRB1578 0.000534 45.4 2DRWY@1|root,33DG4@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k141_775_4 314285.KT71_08279 9.66e-49 160.0 COG1764@1|root,COG1764@2|Bacteria,1RJIP@1224|Proteobacteria,1S6QM@1236|Gammaproteobacteria,1J9ZC@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O redox protein, regulator of disulfide bond formation - - - - - - - - - - - - OsmC k141_24397_1 1453501.JELR01000005_gene1589 1.47e-82 262.0 COG0366@1|root,COG0366@2|Bacteria,1MU90@1224|Proteobacteria,1RQ1S@1236|Gammaproteobacteria,465MB@72275|Alteromonadaceae 1236|Gammaproteobacteria G Alpha-amylase domain malS GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0004556,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009311,GO:0009313,GO:0009987,GO:0016052,GO:0016160,GO:0016787,GO:0016798,GO:0030288,GO:0030313,GO:0030978,GO:0030980,GO:0031975,GO:0042597,GO:0043167,GO:0043169,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044464,GO:0046872,GO:0051691,GO:0051692,GO:0071704,GO:1901575 3.2.1.1 ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 - R02108,R02112,R11262 - ko00000,ko00001,ko01000 - GH13 iECABU_c1320.ECABU_c40140,iECP_1309.ECP_3675,iECSE_1348.ECSE_3847,iPC815.YPO4080,ic_1306.c4392 Alpha-amylase k141_5511_1 1279017.AQYJ01000029_gene3845 1.07e-124 367.0 COG1262@1|root,COG1262@2|Bacteria,1MUNC@1224|Proteobacteria,1RQI4@1236|Gammaproteobacteria,465KE@72275|Alteromonadaceae 1236|Gammaproteobacteria S DinB superfamily egtB - - - - - - - - - - - DinB_2,FGE-sulfatase k141_17251_1 935948.KE386495_gene1727 2.7e-65 221.0 COG0557@1|root,COG0557@2|Bacteria,1TQ1G@1239|Firmicutes,247ZS@186801|Clostridia,42FKG@68295|Thermoanaerobacterales 186801|Clostridia J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs rnr - - ko:K12573 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03016,ko03019 - - - OB_RNB,RNB,S1 k141_27016_1 935836.JAEL01000014_gene2036 3.7e-25 97.8 2ECHY@1|root,336G6@2|Bacteria,1VHDI@1239|Firmicutes,4HQT3@91061|Bacilli,1ZII8@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_35156_1 42565.FP66_08175 1.11e-155 441.0 COG3081@1|root,COG3081@2|Bacteria,1NXJU@1224|Proteobacteria,1RP8N@1236|Gammaproteobacteria,1XKW1@135619|Oceanospirillales 135619|Oceanospirillales S nucleoid-associated protein - - - ko:K06899 - - - - ko00000,ko03036 - - - NA37 k141_10299_1 218284.CCDN010000005_gene3353 9.56e-102 322.0 COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,4HAFP@91061|Bacilli,1ZBJ3@1386|Bacillus 91061|Bacilli V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran k141_36180_1 1042377.AFPJ01000036_gene1173 1.53e-72 241.0 COG0665@1|root,COG4121@1|root,COG0665@2|Bacteria,COG4121@2|Bacteria,1MZW5@1224|Proteobacteria,1RMTE@1236|Gammaproteobacteria,464VK@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 mnmC GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0004808,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016491,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363 2.1.1.61 ko:K15461 - - R00601,R08702 RC00003,RC00053,RC00060,RC01483 ko00000,ko01000,ko03016 - - - DAO,Methyltransf_30 k141_7695_1 1042377.AFPJ01000044_gene632 3.24e-28 108.0 COG1226@1|root,2Z7ZD@2|Bacteria,1MXKM@1224|Proteobacteria,1RNMT@1236|Gammaproteobacteria,464C8@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1226 Kef-type K transport systems - - - ko:K08714 - - - - ko00000,ko02000 1.A.1.14 - - Ion_trans k141_16070_1 218284.CCDN010000001_gene449 1.42e-94 302.0 COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,4HAFP@91061|Bacilli,1ZBJ3@1386|Bacillus 91061|Bacilli V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran k141_10300_1 1453501.JELR01000001_gene3204 1.21e-49 160.0 COG3584@1|root,COG3584@2|Bacteria,1MZPJ@1224|Proteobacteria,1SBH0@1236|Gammaproteobacteria,46BSK@72275|Alteromonadaceae 1236|Gammaproteobacteria S 3D domain protein DR0488 - - - - - - - - - - - - k141_9019_2 1453501.JELR01000001_gene2600 6.65e-32 119.0 COG0491@1|root,COG0491@2|Bacteria,1MURA@1224|Proteobacteria,1RN27@1236|Gammaproteobacteria,464NE@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0491 Zn-dependent hydrolases, including glyoxylases blh - - - - - - - - - - - Lactamase_B k141_32595_2 522373.Smlt3211 5.94e-09 55.5 2ANYG@1|root,31DZF@2|Bacteria,1QB9H@1224|Proteobacteria,1T6TX@1236|Gammaproteobacteria,1X857@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - k141_32595_3 1453501.JELR01000001_gene2815 5.25e-163 465.0 COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,1RMFM@1236|Gammaproteobacteria,464UA@72275|Alteromonadaceae 1236|Gammaproteobacteria L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII dinB GO:0003674,GO:0003824,GO:0003887,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02346 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH k141_22022_1 477184.KYC_28008 3.02e-48 178.0 COG2909@1|root,COG2909@2|Bacteria,1MVZZ@1224|Proteobacteria,2VJ7D@28216|Betaproteobacteria,3T8DC@506|Alcaligenaceae 28216|Betaproteobacteria K helix_turn_helix, Lux Regulon - - - ko:K03556 - - - - ko00000,ko03000 - - - AAA_16,GerE k141_13921_1 1453501.JELR01000002_gene1344 4.08e-90 275.0 COG3712@1|root,COG3712@2|Bacteria,1MZCK@1224|Proteobacteria,1S88I@1236|Gammaproteobacteria,467V5@72275|Alteromonadaceae 1236|Gammaproteobacteria PT Domain of unknown function (DUF4880) - - - ko:K07165 - - - - ko00000 - - - DUF4880,DUF4974,FecR k141_27018_2 218284.CCDN010000001_gene1230 4.97e-101 296.0 COG1284@1|root,COG1284@2|Bacteria,1V3MX@1239|Firmicutes,4HHN4@91061|Bacilli,1ZEF3@1386|Bacillus 91061|Bacilli S Uncharacterised 5xTM membrane BCR, YitT family COG1284 - - - - - - - - - - - - YitT_membrane k141_19714_1 1279017.AQYJ01000026_gene65 1.51e-189 560.0 COG4105@1|root,COG4105@2|Bacteria,1QVQ9@1224|Proteobacteria,1RSIG@1236|Gammaproteobacteria,46DC5@72275|Alteromonadaceae 1236|Gammaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16,TPR_6 k141_19714_2 1279017.AQYJ01000026_gene64 1.3e-51 171.0 COG0457@1|root,COG0457@2|Bacteria,1NB8N@1224|Proteobacteria,1SEZN@1236|Gammaproteobacteria,4697B@72275|Alteromonadaceae 1236|Gammaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_1,TPR_11,TPR_12,TPR_16,TPR_17,TPR_19,TPR_2,TPR_6,TPR_8 k141_19714_3 1453501.JELR01000002_gene347 1.23e-36 126.0 2EQ5T@1|root,32ZV0@2|Bacteria,1NFTI@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_19714_4 1279017.AQYJ01000026_gene62 5.01e-125 362.0 COG0811@1|root,COG0811@2|Bacteria,1PKF8@1224|Proteobacteria,1RRWP@1236|Gammaproteobacteria,465RQ@72275|Alteromonadaceae 1236|Gammaproteobacteria U COG0811 Biopolymer transport proteins - - - - - - - - - - - - MotA_ExbB k141_19714_5 1279017.AQYJ01000026_gene61 2.09e-91 272.0 COG0848@1|root,COG0848@2|Bacteria,1RHI8@1224|Proteobacteria,1S6FK@1236|Gammaproteobacteria,46BMC@72275|Alteromonadaceae 1236|Gammaproteobacteria U Biopolymer transport protein ExbD/TolR - - - - - - - - - - - - ExbD k141_36181_1 1294265.JCM21738_5076 3.45e-38 137.0 COG2256@1|root,COG2256@2|Bacteria,1TPVV@1239|Firmicutes,4HAIS@91061|Bacilli,1ZBCW@1386|Bacillus 91061|Bacilli L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase rarA - - ko:K07478 - - - - ko00000 - - - AAA,AAA_assoc_2,MgsA_C,RuvB_N k141_17253_1 218284.CCDN010000002_gene2609 2.32e-88 270.0 COG1173@1|root,COG1173@2|Bacteria,1V21B@1239|Firmicutes,4HJ5Y@91061|Bacilli,1ZFPK@1386|Bacillus 91061|Bacilli EP ABC transporter (permease) - - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 k141_777_2 1403313.AXBR01000013_gene1349 1.16e-35 129.0 COG0514@1|root,COG0514@2|Bacteria,1UNCK@1239|Firmicutes,4IUA0@91061|Bacilli,1ZSFN@1386|Bacillus 91061|Bacilli L Nuclease-related domain - - - - - - - - - - - - NERD k141_35158_1 268407.PWYN_15645 1.61e-86 266.0 COG1783@1|root,COG1783@2|Bacteria,1TRQP@1239|Firmicutes,4HDMY@91061|Bacilli,26WVX@186822|Paenibacillaceae 91061|Bacilli S Terminase RNAseH like domain - - - ko:K06909 - - - - ko00000 - - - Terminase_3,Terminase_3C k141_7696_1 218284.CCDN010000003_gene2999 1.43e-143 427.0 COG2208@1|root,COG2208@2|Bacteria,1TQ92@1239|Firmicutes,4HB0X@91061|Bacilli,1ZAYZ@1386|Bacillus 91061|Bacilli KT stage II sporulation protein E spoIIE GO:0005575,GO:0005623,GO:0042601,GO:0042763,GO:0044464 3.1.3.16 ko:K06382 - - - - ko00000,ko01000 - - - SpoIIE k141_31397_1 1227360.C176_20539 7.85e-06 55.8 COG0791@1|root,COG0791@2|Bacteria,1V9ZW@1239|Firmicutes,4HDB9@91061|Bacilli,26I8Y@186818|Planococcaceae 1239|Firmicutes M COG0791 Cell wall-associated hydrolases (invasion-associated proteins) ydhO1 - - ko:K21471 - - - - ko00000,ko01000,ko01002,ko01011 - - - Cu_amine_oxidN1,LysM,NLPC_P60,SH3_3 k141_10302_1 1280954.HPO_16645 2.6e-33 129.0 COG2871@1|root,COG2871@2|Bacteria,1QTUV@1224|Proteobacteria,2TWD7@28211|Alphaproteobacteria,440YP@69657|Hyphomonadaceae 28211|Alphaproteobacteria C COG2871 Na -transporting NADH ubiquinone oxidoreductase, subunit NqrF nqrF - 1.6.5.8 ko:K00351,ko:K16246 ko00361,ko00362,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00623,map01100,map01120,map01220 M00548 R03560,R03608,R10042,R10043 RC00046,RC00490 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_6,Fer2,NAD_binding_1,PepSY_TM k141_10302_2 247634.GPB2148_1384 2.84e-83 259.0 COG4188@1|root,COG4188@2|Bacteria,1PXD8@1224|Proteobacteria,1SIKV@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Dienelactone hydrolase - - - - - - - - - - - - - k141_23342_1 1453501.JELR01000002_gene460 6.54e-24 99.8 COG3182@1|root,COG3182@2|Bacteria,1MW2S@1224|Proteobacteria,1RQYY@1236|Gammaproteobacteria,46636@72275|Alteromonadaceae 1236|Gammaproteobacteria S PepSY-associated TM region - - - - - - - - - - - - PepSY_TM k141_23342_2 399739.Pmen_4556 6.74e-216 630.0 COG4773@1|root,COG4773@2|Bacteria,1MW5E@1224|Proteobacteria,1RMBD@1236|Gammaproteobacteria 1236|Gammaproteobacteria P receptor fhuE - - ko:K16088 - - - - ko00000,ko02000 1.B.14.1.10,1.B.14.1.3,1.B.14.1.8 - - Plug,TonB_dep_Rec k141_13922_2 1120970.AUBZ01000003_gene163 1.55e-57 200.0 COG4191@1|root,COG4191@2|Bacteria,1MU55@1224|Proteobacteria,1RQ5N@1236|Gammaproteobacteria,4643T@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0642 Signal transduction histidine kinase prsK - - - - - - - - - - - GAF_2,HATPase_c k141_9022_1 218284.CCDN010000006_gene3715 6.51e-53 174.0 COG1396@1|root,COG1396@2|Bacteria,1V1KD@1239|Firmicutes,4HG1Q@91061|Bacilli,1ZEYC@1386|Bacillus 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_19,HTH_3,TPR_12,TPR_8 k141_30204_1 218284.CCDN010000003_gene3001 2.02e-90 273.0 COG0515@1|root,COG0515@2|Bacteria,1TSNS@1239|Firmicutes,4HBDI@91061|Bacilli,1ZBVA@1386|Bacillus 91061|Bacilli KLT serine threonine protein kinase yabT - 2.7.11.1 ko:K08884 - - - - ko00000,ko01000,ko01001 - - - Pkinase k141_27020_1 218284.CCDN010000007_gene3875 1.73e-125 361.0 COG0154@1|root,COG0154@2|Bacteria,1UZ2V@1239|Firmicutes,4HE70@91061|Bacilli,1ZDE6@1386|Bacillus 91061|Bacilli J Gas vesicle synthesis protein GvpL/GvpF - - - - - - - - - - - - GvpL_GvpF k141_7697_1 218284.CCDN010000004_gene3026 5.93e-110 321.0 COG1191@1|root,COG1191@2|Bacteria,1TP3Q@1239|Firmicutes,4HBIW@91061|Bacilli,1ZBAP@1386|Bacillus 91061|Bacilli K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released sigB GO:0000988,GO:0000990,GO:0003674,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043254,GO:0043620,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - ko:K03090 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r3,Sigma70_r4 k141_36199_1 1453501.JELR01000001_gene2856 1.02e-105 328.0 COG1472@1|root,COG1472@2|Bacteria,1MVIV@1224|Proteobacteria,1RMA0@1236|Gammaproteobacteria,465BV@72275|Alteromonadaceae 1236|Gammaproteobacteria G Family 3 - - 3.2.1.21 ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 - R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - GH3 - Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C,Lipase_GDSL_2 k141_2941_1 1201290.M902_2576 2.19e-71 228.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,42N7F@68525|delta/epsilon subdivisions,2MSTM@213481|Bdellovibrionales,2WJB2@28221|Deltaproteobacteria 213481|Bdellovibrionales I Belongs to the thiolase family fadI - 2.3.1.16,2.3.1.9 ko:K00626,ko:K00632 ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00087,M00088,M00095,M00113,M00373,M00374,M00375 R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095 RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N k141_37393_1 198467.NP92_14625 1.86e-52 168.0 COG0346@1|root,COG0346@2|Bacteria,1VAEF@1239|Firmicutes,4HGTX@91061|Bacilli,21X0J@150247|Anoxybacillus 91061|Bacilli E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - Glyoxalase k141_18610_1 1279017.AQYJ01000027_gene1657 3.69e-42 150.0 COG4148@1|root,COG4148@2|Bacteria,1MU8K@1224|Proteobacteria,1RQCV@1236|Gammaproteobacteria,464HI@72275|Alteromonadaceae 1236|Gammaproteobacteria P Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system modC GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0008144,GO:0008150,GO:0008509,GO:0015075,GO:0015098,GO:0015103,GO:0015318,GO:0015399,GO:0015405,GO:0015412,GO:0015689,GO:0015698,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043225,GO:0043492,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0097159,GO:0097367,GO:0098656,GO:0099133,GO:1901265,GO:1901363 3.6.3.29 ko:K02017 ko02010,map02010 M00189 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.8 - iECNA114_1301.ECNA114_0696,iECSF_1327.ECSF_0691,iUMNK88_1353.UMNK88_805 ABC_tran,TOBE k141_18610_2 1453501.JELR01000001_gene2912 8.11e-115 336.0 COG0476@1|root,COG0476@2|Bacteria,1MW7H@1224|Proteobacteria,1RPJ3@1236|Gammaproteobacteria,466BQ@72275|Alteromonadaceae 1236|Gammaproteobacteria H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 moeB - 2.7.7.73,2.7.7.80 ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07459 RC00043 ko00000,ko00001,ko01000 - - - ThiF k141_11609_1 1294265.JCM21738_1782 4.53e-65 202.0 COG2864@1|root,COG2864@2|Bacteria,1V757@1239|Firmicutes,4I18J@91061|Bacilli,1ZDA7@1386|Bacillus 91061|Bacilli C COG2864 Cytochrome b subunit of formate dehydrogenase - - - ko:K00127 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001 - - - Ni_hydr_CYTB k141_11609_2 1294265.JCM21738_1781 2.83e-196 543.0 COG3058@1|root,COG3058@2|Bacteria,1VJXM@1239|Firmicutes,4HZH7@91061|Bacilli,1ZEIG@1386|Bacillus 91061|Bacilli O Necessary for formate dehydrogenase activity - - - ko:K02380 - - - - ko00000 - - - FdhE k141_11609_3 1294265.JCM21738_1780 0.000946 40.4 COG0746@1|root,COG0746@2|Bacteria,1VA6T@1239|Firmicutes,4HPX3@91061|Bacilli,1ZIA7@1386|Bacillus 91061|Bacilli H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor mobA - 2.7.7.77 ko:K03752 ko00790,ko01100,map00790,map01100 - R11581 - ko00000,ko00001,ko01000 - - - NTP_transf_3 k141_3043_1 1444310.JANV01000026_gene4101 2.43e-105 320.0 COG1053@1|root,COG1053@2|Bacteria,1TPAR@1239|Firmicutes,4HBVG@91061|Bacilli,1ZBRD@1386|Bacillus 91061|Bacilli C succinate dehydrogenase sdhA GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0022900,GO:0044237,GO:0045333,GO:0055114 1.3.5.1,1.3.5.4 ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS05640 FAD_binding_2,Succ_DH_flav_C k141_9191_1 234267.Acid_7172 4.25e-38 147.0 COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,3Y7WS@57723|Acidobacteria 57723|Acidobacteria T Protein tyrosine kinase - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - Pkinase k141_18765_1 1279017.AQYJ01000019_gene1495 4.92e-247 700.0 COG0642@1|root,COG0642@2|Bacteria,1QU3Z@1224|Proteobacteria,1T311@1236|Gammaproteobacteria,46D2F@72275|Alteromonadaceae 1236|Gammaproteobacteria T Histidine kinase - - - - - - - - - - - - CBM9_1,HATPase_c,HisKA k141_18765_2 1453501.JELR01000005_gene1767 1e-133 382.0 COG0745@1|root,COG0745@2|Bacteria,1MVCB@1224|Proteobacteria,1RM87@1236|Gammaproteobacteria,465DT@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain chvI GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042802,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - ko:K02483,ko:K07663 ko02020,map02020 M00449 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C k141_18765_3 1279017.AQYJ01000019_gene1498 2.38e-106 313.0 COG2885@1|root,COG2885@2|Bacteria,1RIG3@1224|Proteobacteria,1S5WW@1236|Gammaproteobacteria,46CH4@72275|Alteromonadaceae 1236|Gammaproteobacteria M OmpA family - - - - - - - - - - - - DUF4398,OmpA k141_22201_1 42565.FP66_12185 1.19e-116 342.0 COG1960@1|root,COG1960@2|Bacteria,1MUK0@1224|Proteobacteria,1RNBX@1236|Gammaproteobacteria,1XI9Y@135619|Oceanospirillales 135619|Oceanospirillales I acyl-CoA dehydrogenase - - 1.3.8.6 ko:K00252 ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130 M00032 R02487,R02488,R10074 RC00052,RC00156 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_19846_1 485913.Krac_4677 1.19e-05 46.6 COG1733@1|root,COG1733@2|Bacteria,2G792@200795|Chloroflexi 200795|Chloroflexi K PFAM helix-turn-helix HxlR type - - - - - - - - - - - - HxlR k141_24603_1 1042377.AFPJ01000016_gene121 7.21e-129 386.0 COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,1RNA5@1236|Gammaproteobacteria,4641A@72275|Alteromonadaceae 1236|Gammaproteobacteria P Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity katG GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.11.1.21 ko:K03782 ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110 - R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906 RC00034,RC00213,RC00767,RC02141 ko00000,ko00001,ko01000 - - - peroxidase k141_14122_1 218284.CCDN010000001_gene1254 4.17e-87 262.0 COG1968@1|root,COG1968@2|Bacteria,1TPFA@1239|Firmicutes,4HCE7@91061|Bacilli,1ZC3Z@1386|Bacillus 91061|Bacilli V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin uppP - 3.6.1.27 ko:K06153 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - BacA k141_14122_2 218284.CCDN010000001_gene1253 3.42e-110 320.0 COG0586@1|root,COG0586@2|Bacteria,1V1D4@1239|Firmicutes,4HFSU@91061|Bacilli,1ZCPB@1386|Bacillus 91061|Bacilli S membrane-associated protein yngC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - SNARE_assoc k141_18810_1 218284.CCDN010000001_gene1340 1.01e-128 370.0 COG0714@1|root,COG0714@2|Bacteria,1TQJA@1239|Firmicutes,4HBG4@91061|Bacilli,1ZAT6@1386|Bacillus 91061|Bacilli S ATPase family associated with various cellular activities (AAA) yojN - - ko:K04748 - - R00294 RC02794 ko00000 3.D.4.10 - - AAA_5,CbbQ_C k141_6785_4 1279017.AQYJ01000020_gene1267 1.54e-291 810.0 COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,1RMGA@1236|Gammaproteobacteria,46478@72275|Alteromonadaceae 1236|Gammaproteobacteria L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG GO:0003674,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB_bind,DnaG_DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2 k141_14966_1 742159.HMPREF0004_0993 3.47e-15 80.9 COG3209@1|root,COG5295@1|root,COG3209@2|Bacteria,COG5295@2|Bacteria,1QW4H@1224|Proteobacteria,2WHVG@28216|Betaproteobacteria 28216|Betaproteobacteria M Rhs Family - - - - - - - - - - - - - k141_10401_1 1294265.JCM21738_5225 8.52e-136 405.0 COG0464@1|root,COG0464@2|Bacteria,1TPQZ@1239|Firmicutes,4HCQK@91061|Bacilli,1ZCWD@1386|Bacillus 91061|Bacilli O stage V sporulation protein K spoVK_1 - - - - - - - - - - - AAA k141_27217_1 218284.CCDN010000001_gene545 1.33e-37 129.0 COG4508@1|root,COG4508@2|Bacteria,1V6PI@1239|Firmicutes,4HJBB@91061|Bacilli,1ZGXN@1386|Bacillus 91061|Bacilli S dUTPase - - - - - - - - - - - - dUTPase_2 k141_27217_2 218284.CCDN010000001_gene546 8.75e-62 198.0 COG1363@1|root,COG1363@2|Bacteria,1TNZT@1239|Firmicutes,4H9SM@91061|Bacilli,1ZD06@1386|Bacillus 91061|Bacilli G COG1363 Cellulase M and related proteins ysdC - - - - - - - - - - - Peptidase_M42 k141_32759_1 1033802.SSPSH_000920 9.82e-14 76.3 COG2856@1|root,COG2856@2|Bacteria,1PFUN@1224|Proteobacteria,1RR40@1236|Gammaproteobacteria 1236|Gammaproteobacteria E IrrE N-terminal-like domain - - - - - - - - - - - - Peptidase_M78 k141_19847_1 935836.JAEL01000008_gene3940 1.16e-69 225.0 COG0168@1|root,COG0168@2|Bacteria,1TQ4S@1239|Firmicutes,4H9ME@91061|Bacilli,1ZBJ9@1386|Bacillus 91061|Bacilli P Potassium ktrB_3 - - ko:K03498 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkH k141_3073_1 1340434.AXVA01000008_gene3829 2.29e-88 264.0 COG0217@1|root,COG0217@2|Bacteria,1TPP5@1239|Firmicutes,4H9WJ@91061|Bacilli,1ZBN0@1386|Bacillus 91061|Bacilli K transcriptional regulatory protein yeeN GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - - - - - - - - - - Transcrip_reg k141_12844_1 1122134.KB893650_gene1288 2.98e-49 164.0 COG1266@1|root,COG1266@2|Bacteria 2|Bacteria V CAAX protease self-immunity - - - ko:K07052 - - - - ko00000 - - - Abi k141_35326_3 1279017.AQYJ01000027_gene1576 1.6e-148 422.0 COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,1RSQ3@1236|Gammaproteobacteria,465W6@72275|Alteromonadaceae 1236|Gammaproteobacteria P Rhodanese Homology Domain rhdA - 2.8.1.1,2.8.1.2 ko:K01011 ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122 - R01931,R03105,R03106 RC00214 ko00000,ko00001,ko01000 - - - Rhodanese k141_25871_1 672.VV93_v1c20920 5.34e-05 51.2 COG3710@1|root,COG3710@2|Bacteria,1R52Q@1224|Proteobacteria,1RQY5@1236|Gammaproteobacteria,1XVDH@135623|Vibrionales 135623|Vibrionales K Transcriptional activator CadC cadC - - ko:K03765 - - - - ko00000,ko03000 - - - Trans_reg_C k141_14123_2 1279017.AQYJ01000028_gene2453 2.52e-142 408.0 COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,1RQJD@1236|Gammaproteobacteria,466WW@72275|Alteromonadaceae 1236|Gammaproteobacteria K Bacterial regulatory helix-turn-helix protein, lysR family - - - ko:K21703 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate k141_6787_1 252305.OB2597_13013 2.43e-42 159.0 COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,2TT4K@28211|Alphaproteobacteria,2PD9D@252301|Oceanicola 28211|Alphaproteobacteria M nucleoside-diphosphate sugar epimerases lpsB2 GO:0008150,GO:0043900,GO:0043902,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0065007,GO:1900190,GO:1900192 - - - - - - - - - - CoA_binding_3,Polysacc_synt_2 k141_23539_1 1279017.AQYJ01000023_gene3292 3.49e-190 566.0 COG3325@1|root,COG3979@1|root,COG3325@2|Bacteria,COG3979@2|Bacteria,1R3YZ@1224|Proteobacteria,1RY6I@1236|Gammaproteobacteria,46AA7@72275|Alteromonadaceae 1236|Gammaproteobacteria G Chitinase C - - 3.2.1.14,3.2.1.202 ko:K01183,ko:K21606 ko00520,ko01100,map00520,map01100 - R01206,R02334 RC00467 ko00000,ko00001,ko01000 - CBM5,GH18 - CBM_5_12_2,ChiC,Glyco_hydro_18 k141_27219_1 1040989.AWZU01000136_gene2097 2.11e-114 334.0 COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,2U1Z0@28211|Alphaproteobacteria,3JW1X@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L Reverse transcriptase (RNA-dependent DNA polymerase) - - 2.7.7.49 ko:K00986,ko:K15342 - - - - ko00000,ko01000,ko02048,ko03400 - - - Cas_Cas1,GIIM,RVT_1 k141_7863_1 935836.JAEL01000003_gene465 3.02e-90 270.0 COG4565@1|root,COG4565@2|Bacteria,1V1D7@1239|Firmicutes,4HFWB@91061|Bacilli,1ZFEC@1386|Bacillus 91061|Bacilli T response regulator citT - - ko:K11638 ko02020,map02020 M00487 - - ko00000,ko00001,ko00002,ko02022 - - - CitT,HTH_11,Response_reg k141_14124_1 218284.CCDN010000001_gene1745 9.31e-112 327.0 28JAJ@1|root,2Z95C@2|Bacteria,1UBFJ@1239|Firmicutes,4HHFM@91061|Bacilli,1ZR76@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_9222_1 218284.CCDN010000007_gene3822 7.08e-158 454.0 COG0754@1|root,COG0754@2|Bacteria,1UTUT@1239|Firmicutes,4HBAJ@91061|Bacilli,1ZB3R@1386|Bacillus 91061|Bacilli E Glutathionylspermidine synthase preATP-grasp - - - - - - - - - - - - GSP_synth k141_25872_1 1294265.JCM21738_5247 6.63e-101 308.0 COG1293@1|root,COG1293@2|Bacteria,1TQ8A@1239|Firmicutes,4H9UF@91061|Bacilli,1ZBGD@1386|Bacillus 91061|Bacilli K RNA-binding protein homologous to eukaryotic snRNP FbpA - - - - - - - - - - - DUF814,FbpA k141_31464_1 935836.JAEL01000050_gene5408 1.36e-173 495.0 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli,1ZAXK@1386|Bacillus 91061|Bacilli C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively iolA - 1.2.1.18,1.2.1.27 ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 M00013 R00705,R00706,R00922,R00935 RC00004,RC02723,RC02817 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_12845_1 1116375.VEJY3_08255 7.27e-67 210.0 COG0697@1|root,COG0697@2|Bacteria,1MY0D@1224|Proteobacteria,1S001@1236|Gammaproteobacteria,1XV8D@135623|Vibrionales 135623|Vibrionales EG of the drug metabolite transporter (DMT) superfamily - - - - - - - - - - - - EamA k141_23540_1 1219076.N646_1258 2.89e-147 432.0 COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,1RNM8@1236|Gammaproteobacteria,1XTNT@135623|Vibrionales 135623|Vibrionales C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family fadH - 1.3.1.34 ko:K00219 - - - - ko00000,ko01000 - - - Oxidored_FMN,Pyr_redox_2 k141_14967_1 1379270.AUXF01000006_gene184 3.13e-189 542.0 COG4799@1|root,COG4799@2|Bacteria,1ZTGB@142182|Gemmatimonadetes 142182|Gemmatimonadetes I Carboxyl transferase domain - - - - - - - - - - - - Carboxyl_trans k141_3075_1 1499680.CCFE01000025_gene3320 9.71e-115 338.0 COG0823@1|root,COG0823@2|Bacteria,1UY6R@1239|Firmicutes,4HFFZ@91061|Bacilli,1ZRV0@1386|Bacillus 91061|Bacilli U Involved in the tonB-independent uptake of proteins - - - - - - - - - - - - PD40 k141_6788_1 218284.CCDN010000001_gene1169 5.28e-138 396.0 COG1028@1|root,COG1028@2|Bacteria,1TPZ8@1239|Firmicutes,4HAMW@91061|Bacilli,1ZQ68@1386|Bacillus 91061|Bacilli IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - - - - - - - - - - adh_short_C2 k141_10402_1 1169144.KB910952_gene3212 2.1e-56 184.0 COG1011@1|root,COG1011@2|Bacteria,1TRP5@1239|Firmicutes,4HBSP@91061|Bacilli,1ZDNA@1386|Bacillus 91061|Bacilli S Haloacid dehalogenase-like hydrolase - - - ko:K07025 - - - - ko00000 - - - HAD_2 k141_18815_1 218284.CCDN010000001_gene1012 1.37e-53 179.0 COG1215@1|root,COG1215@2|Bacteria,1UYDS@1239|Firmicutes,4HD6I@91061|Bacilli,1ZPVD@1386|Bacillus 91061|Bacilli M COG0463 Glycosyltransferases involved in cell wall biogenesis - - - - - - - - - - - - Glycos_transf_2 k141_19849_2 1069080.KB913028_gene1297 9.18e-26 106.0 COG3187@1|root,COG3187@2|Bacteria,1UMA9@1239|Firmicutes 1239|Firmicutes O Heat shock protein - - - - - - - - - - - - - k141_35328_1 218284.CCDN010000002_gene2413 2.49e-58 185.0 COG2808@1|root,COG2808@2|Bacteria,1TXED@1239|Firmicutes,4HEZS@91061|Bacilli,1ZDPR@1386|Bacillus 91061|Bacilli K Transcriptional regulator paiB - - ko:K07734 - - - - ko00000,ko03000 - - - FMN_bind_2 k141_35328_2 324057.Pjdr2_6169 2.4e-30 110.0 COG3795@1|root,COG3795@2|Bacteria,1VGEK@1239|Firmicutes,4HQ2I@91061|Bacilli 91061|Bacilli S YCII-related domain - - - - - - - - - - - - YCII k141_23541_2 1453501.JELR01000001_gene2968 0.000341 42.4 COG0319@1|root,COG0319@2|Bacteria,1MZ67@1224|Proteobacteria,1S6BS@1236|Gammaproteobacteria,467I5@72275|Alteromonadaceae 1236|Gammaproteobacteria J Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ybeY GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - ko:K07042 - - - - ko00000,ko03009 - - - UPF0054 k141_29280_3 1279017.AQYJ01000027_gene1627 1.34e-53 170.0 COG1965@1|root,COG1965@2|Bacteria,1RH9A@1224|Proteobacteria,1S5UP@1236|Gammaproteobacteria,467XI@72275|Alteromonadaceae 1236|Gammaproteobacteria P Belongs to the frataxin family cyaY GO:0003674,GO:0003824,GO:0004322,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006790,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008198,GO:0008199,GO:0009987,GO:0016043,GO:0016226,GO:0016491,GO:0016530,GO:0016722,GO:0016724,GO:0018282,GO:0018283,GO:0019538,GO:0019725,GO:0022607,GO:0030003,GO:0031163,GO:0033554,GO:0034599,GO:0034986,GO:0036211,GO:0042221,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0050896,GO:0051186,GO:0051536,GO:0051537,GO:0051540,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071704,GO:0071840,GO:0098771,GO:0140104,GO:1901564 - ko:K06202 - - - - ko00000 - - iECW_1372.ECW_m4108,iEKO11_1354.EKO11_4552,iWFL_1372.ECW_m4108 Frataxin_Cyay k141_29280_5 1279017.AQYJ01000027_gene1625 3.15e-151 439.0 COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,1RQDA@1236|Gammaproteobacteria,4666A@72275|Alteromonadaceae 1236|Gammaproteobacteria T signal transduction protein with a C-terminal ATPase domain algZ - 2.7.13.3 ko:K08082 ko02020,map02020 M00493 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - His_kinase k141_29280_6 1279017.AQYJ01000027_gene1624 8.68e-100 298.0 COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,1RMJJ@1236|Gammaproteobacteria,466SZ@72275|Alteromonadaceae 1236|Gammaproteobacteria KT COG3279 Response regulator of the LytR AlgR family algR - - ko:K08083 ko02020,map02020 M00493 - - ko00000,ko00001,ko00002,ko02022 - - - LytTR,Response_reg k141_29280_7 439235.Dalk_2897 2.35e-16 91.3 COG5184@1|root,COG5276@1|root,COG5184@2|Bacteria,COG5276@2|Bacteria,1R504@1224|Proteobacteria,42QHC@68525|delta/epsilon subdivisions,2WKUI@28221|Deltaproteobacteria 28221|Deltaproteobacteria DZ Alpha-tubulin suppressor and related RCC1 domain-containing proteins - - - - - - - - - - - - RCC1,RCC1_2 k141_16211_1 218284.CCDN010000002_gene2132 4.43e-149 432.0 COG1574@1|root,COG1574@2|Bacteria,1TQ6G@1239|Firmicutes,4H9T6@91061|Bacilli,1ZC1J@1386|Bacillus 91061|Bacilli S Amidohydrolase family ytcJ - - - - - - - - - - - Amidohydro_3 k141_23542_1 545693.BMQ_1270 1.49e-70 229.0 COG0697@1|root,COG0697@2|Bacteria,1TP7K@1239|Firmicutes,4HAH1@91061|Bacilli,1ZBEF@1386|Bacillus 91061|Bacilli EG Spore germination protein gerKA - - ko:K06295 - - - - ko00000 - - - GerA k141_18817_1 218284.CCDN010000001_gene1530 5.3e-77 231.0 COG1051@1|root,COG1051@2|Bacteria,1VBCP@1239|Firmicutes,4HMIG@91061|Bacilli,1ZHZ2@1386|Bacillus 91061|Bacilli F Belongs to the Nudix hydrolase family - - - - - - - - - - - - NUDIX k141_31465_1 218284.CCDN010000001_gene1875 9.55e-168 476.0 COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,4HADX@91061|Bacilli,1ZBSQ@1386|Bacillus 91061|Bacilli E Belongs to the aspartokinase family dapG GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,ACT_7 k141_1866_1 1279017.AQYJ01000028_gene2175 1.3e-95 290.0 COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,1RQR7@1236|Gammaproteobacteria,4668G@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria ycbB GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0006508,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0008236,GO:0008238,GO:0009273,GO:0009987,GO:0016740,GO:0016746,GO:0016755,GO:0016787,GO:0016807,GO:0017171,GO:0019538,GO:0033554,GO:0042546,GO:0043164,GO:0043170,GO:0044036,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0050896,GO:0051716,GO:0070004,GO:0070008,GO:0070011,GO:0071554,GO:0071704,GO:0071840,GO:0071972,GO:0140096,GO:1901564 - ko:K21470 - - - - ko00000,ko01002,ko01011 - - - PG_binding_1,YkuD k141_1866_2 1453501.JELR01000002_gene682 2.23e-138 407.0 COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,1RQR7@1236|Gammaproteobacteria,4668G@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria ycbB GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0006508,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0008236,GO:0008238,GO:0009273,GO:0009987,GO:0016740,GO:0016746,GO:0016755,GO:0016787,GO:0016807,GO:0017171,GO:0019538,GO:0033554,GO:0042546,GO:0043164,GO:0043170,GO:0044036,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0050896,GO:0051716,GO:0070004,GO:0070008,GO:0070011,GO:0071554,GO:0071704,GO:0071840,GO:0071972,GO:0140096,GO:1901564 - ko:K21470 - - - - ko00000,ko01002,ko01011 - - - PG_binding_1,YkuD k141_14968_1 218284.CCDN010000005_gene3274 1.13e-95 289.0 COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,4H9SD@91061|Bacilli,1ZD02@1386|Bacillus 91061|Bacilli I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP fabF - 2.3.1.179 ko:K09458,ko:K14660 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - iSB619.SA_RS04785 Ketoacyl-synt_C,ketoacyl-synt k141_14968_2 218284.CCDN010000005_gene3275 2.26e-62 198.0 COG5504@1|root,COG5504@2|Bacteria,1UYP6@1239|Firmicutes,4HFSY@91061|Bacilli,1ZCYK@1386|Bacillus 91061|Bacilli O Zn-dependent protease yjaZ - - - - - - - - - - - DUF2268 k141_22208_1 218284.CCDN010000001_gene1242 4.44e-28 113.0 COG2340@1|root,COG2340@2|Bacteria,1V6GZ@1239|Firmicutes,4HJ21@91061|Bacilli,1ZDSK@1386|Bacillus 91061|Bacilli J protein with SCP PR1 domains ykwD - - - - - - - - - - - CAP k141_4302_1 1051646.VITU9109_04027 7.35e-178 501.0 COG0111@1|root,COG0111@2|Bacteria,1MW0R@1224|Proteobacteria,1RQD6@1236|Gammaproteobacteria,1XTYB@135623|Vibrionales 135623|Vibrionales C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family - - 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C k141_4302_2 1051646.VITU9109_04022 2.07e-34 122.0 COG3981@1|root,COG3981@2|Bacteria,1RIGX@1224|Proteobacteria,1S7UW@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_3 k141_35351_1 1453501.JELR01000002_gene339 1.23e-216 617.0 COG1629@1|root,COG4771@2|Bacteria,1MUPZ@1224|Proteobacteria,1RMMP@1236|Gammaproteobacteria,464D4@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport acr - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_27253_1 1123252.ATZF01000042_gene2260 3.8e-72 224.0 COG2207@1|root,COG3708@1|root,COG2207@2|Bacteria,COG3708@2|Bacteria,1UWKD@1239|Firmicutes,4I2MY@91061|Bacilli,27CPY@186824|Thermoactinomycetaceae 91061|Bacilli K helix_turn_helix, arabinose operon control protein - - - - - - - - - - - - HTH_18 k141_20906_1 1294265.JCM21738_2997 1.37e-62 197.0 COG0847@1|root,COG0847@2|Bacteria,1V38D@1239|Firmicutes,4HFWJ@91061|Bacilli,1ZCI3@1386|Bacillus 91061|Bacilli L COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases polC1 - 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - RNase_T k141_20906_2 997296.PB1_04635 9.24e-29 112.0 COG2905@1|root,COG2905@2|Bacteria,1TQFI@1239|Firmicutes,4HERY@91061|Bacilli,1ZBE8@1386|Bacillus 91061|Bacilli T Putative nucleotidyltransferase substrate binding domain - - - ko:K07182 - - - - ko00000 - - - DUF294,DUF294_C k141_22238_1 768066.HELO_4078 3.54e-35 123.0 COG3157@1|root,COG3157@2|Bacteria,1MXFB@1224|Proteobacteria,1RNKQ@1236|Gammaproteobacteria,1XMG1@135619|Oceanospirillales 135619|Oceanospirillales S Type VI secretion system effector, Hcp - - - ko:K11903 ko02025,ko03070,map02025,map03070 M00334 - - ko00000,ko00001,ko00002,ko02044 - - - T6SS_HCP k141_22238_2 42565.FP66_11965 1.24e-20 89.0 COG2269@1|root,COG2269@2|Bacteria,1MU97@1224|Proteobacteria,1RMR9@1236|Gammaproteobacteria,1XH93@135619|Oceanospirillales 135619|Oceanospirillales J Elongation factor P--(R)-beta-lysine ligase genX - - ko:K04568 - - - - ko00000,ko01000,ko03012 - - - tRNA-synt_2 k141_3097_1 1121921.KB898706_gene3073 3.11e-68 218.0 COG0008@1|root,COG0008@2|Bacteria,1MUN7@1224|Proteobacteria,1RMYQ@1236|Gammaproteobacteria,2PNHR@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria J tRNA synthetases class I (E and Q), catalytic domain gluQ GO:0000166,GO:0002097,GO:0003674,GO:0005488,GO:0005524,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 - ko:K01894 - - - - ko00000,ko01000,ko01007,ko03016 - - - tRNA-synt_1c k141_31474_1 981383.AEWH01000060_gene1995 1.01e-44 158.0 COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,4H9R3@91061|Bacilli 91061|Bacilli F Belongs to the phosphoglycerate kinase family pgk GO:0001871,GO:0002020,GO:0003674,GO:0003824,GO:0004618,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009893,GO:0009986,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019222,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030162,GO:0030193,GO:0030195,GO:0030246,GO:0030247,GO:0030312,GO:0031323,GO:0031325,GO:0032101,GO:0032102,GO:0032268,GO:0032270,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043532,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0045862,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048518,GO:0048519,GO:0048522,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050818,GO:0050819,GO:0050878,GO:0051171,GO:0051173,GO:0051186,GO:0051188,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051917,GO:0051919,GO:0055086,GO:0060255,GO:0061041,GO:0061045,GO:0065007,GO:0065008,GO:0070613,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0080134,GO:0090407,GO:1900046,GO:1900047,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903034,GO:1903035,GO:1903317,GO:1903319,GO:2001065 2.7.2.3 ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01512 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000,ko04147 - - iSB619.SA_RS04145 PGK k141_12854_2 646529.Desaci_1530 1.81e-47 172.0 COG2247@1|root,COG2247@2|Bacteria,1VDZC@1239|Firmicutes 1239|Firmicutes M Cell wall binding repeat 2 - - - ko:K20276 ko02024,map02024 - - - ko00000,ko00001 - - - Amidase_2,Big_2,CW_binding_2,DUF4430 k141_27254_1 926550.CLDAP_14290 2.26e-100 301.0 COG4177@1|root,COG4177@2|Bacteria,2G6HP@200795|Chloroflexi 200795|Chloroflexi P Belongs to the binding-protein-dependent transport system permease family - - - ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 k141_23567_1 218284.CCDN010000001_gene1307 1.1e-227 630.0 COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,4H9SR@91061|Bacilli,1ZCDX@1386|Bacillus 91061|Bacilli S transporter activity yueF GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - - - - - - - - - - AI-2E_transport k141_23567_2 218284.CCDN010000001_gene1308 7.62e-60 202.0 COG0697@1|root,COG0697@2|Bacteria,1TP7K@1239|Firmicutes,4HAH1@91061|Bacilli,1ZBEF@1386|Bacillus 91061|Bacilli EG Spore germination protein gerAA_1 - - ko:K06295 - - - - ko00000 - - - GerA k141_36286_1 1294265.JCM21738_5091 2.25e-160 456.0 COG1600@1|root,COG1600@2|Bacteria,1TP6Q@1239|Firmicutes,4HAEW@91061|Bacilli,1ZC1W@1386|Bacillus 91061|Bacilli C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) queG GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 ko:K18979 - - - - ko00000,ko01000,ko03016 - - - DUF1730,Fer4_16,HEAT_2 k141_19874_1 218284.CCDN010000005_gene3420 6.87e-105 310.0 COG1252@1|root,COG1252@2|Bacteria,1TPE6@1239|Firmicutes,4H9MY@91061|Bacilli,1ZC0V@1386|Bacillus 91061|Bacilli C NADH dehydrogenase yutJ - 1.6.99.3 ko:K03885 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - Pyr_redox_2 k141_7879_1 265729.GS18_0219810 3.95e-50 166.0 COG2966@1|root,COG2966@2|Bacteria,1TSE8@1239|Firmicutes,4HBW1@91061|Bacilli,1ZBTT@1386|Bacillus 91061|Bacilli S Putative threonine/serine exporter yjjP - - - - - - - - - - - ThrE k141_16224_2 1453501.JELR01000001_gene2606 1.19e-18 84.3 2DFIW@1|root,32U5K@2|Bacteria,1N3SV@1224|Proteobacteria,1S9V3@1236|Gammaproteobacteria,468SS@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF4919) - - - - - - - - - - - - DUF4919 k141_25902_1 1453501.JELR01000002_gene1090 4.04e-95 284.0 COG0169@1|root,COG0169@2|Bacteria,1MVH4@1224|Proteobacteria,1RPB7@1236|Gammaproteobacteria,4647Q@72275|Alteromonadaceae 1236|Gammaproteobacteria E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) aroE GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_3165,iECOK1_1307.ECOK1_3701,iECS88_1305.ECS88_3669,iECUMN_1333.ECUMN_3755,iSBO_1134.SBO_3275,iUMN146_1321.UM146_16315,iUTI89_1310.UTI89_C3726 Shikimate_DH,Shikimate_dh_N k141_6807_1 360911.EAT1b_0041 1.21e-44 178.0 COG5280@1|root,COG5283@1|root,COG5280@2|Bacteria,COG5283@2|Bacteria,1UHQM@1239|Firmicutes,4ITE3@91061|Bacilli 91061|Bacilli M Phage-related minor tail protein - - - - - - - - - - - - PhageMin_Tail k141_29452_1 1116375.VEJY3_08275 3.72e-79 241.0 COG0388@1|root,COG0388@2|Bacteria,1MXG5@1224|Proteobacteria,1RP7S@1236|Gammaproteobacteria,1XSG7@135623|Vibrionales 135623|Vibrionales S Carbon-nitrogen hydrolase - - 3.5.1.53 ko:K12251 ko00330,ko01100,map00330,map01100 - R01152 RC00096 ko00000,ko00001,ko01000 - - - CN_hydrolase k141_29452_2 1116375.VEJY3_08270 3.03e-255 700.0 COG2957@1|root,COG2957@2|Bacteria,1MX65@1224|Proteobacteria,1RMF1@1236|Gammaproteobacteria,1XVYW@135623|Vibrionales 135623|Vibrionales E agmatine deiminase aguA - 3.5.3.12 ko:K10536 ko00330,ko01100,map00330,map01100 - R01416 RC00177 ko00000,ko00001,ko01000 - - - PAD_porph k141_35536_1 223926.28807104 1.02e-160 454.0 COG2885@1|root,COG2885@2|Bacteria,1PGGZ@1224|Proteobacteria,1RNFU@1236|Gammaproteobacteria,1XUNB@135623|Vibrionales 135623|Vibrionales N flagellar protein MotY motY - - ko:K21218 ko02040,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - OmpA k141_35536_2 1116375.VEJY3_10965 4.66e-150 422.0 COG0847@1|root,COG0847@2|Bacteria,1MUPK@1224|Proteobacteria,1RMMH@1236|Gammaproteobacteria,1XUNE@135623|Vibrionales 135623|Vibrionales L Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis rnt GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0031123,GO:0034470,GO:0034641,GO:0034660,GO:0042780,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 - ko:K03683 - - - - ko00000,ko01000,ko03016 - - - RNase_T k141_35536_3 1116375.VEJY3_10970 3.82e-158 454.0 COG2056@1|root,COG2056@2|Bacteria,1N8U2@1224|Proteobacteria,1RRW5@1236|Gammaproteobacteria,1XSSP@135623|Vibrionales 135623|Vibrionales S Na+-H+ antiporter family - - - ko:K07084 - - - - ko00000,ko02000 2.A.8.1.12 - - Na_H_antiport_2,Na_H_antiporter k141_32974_1 1279017.AQYJ01000024_gene983 6.1e-252 699.0 COG1167@1|root,COG1167@2|Bacteria,1MUUI@1224|Proteobacteria,1RQDS@1236|Gammaproteobacteria,464U4@72275|Alteromonadaceae 1236|Gammaproteobacteria EK Alanine-glyoxylate amino-transferase aspC - - - - - - - - - - - Aminotran_MocR k141_12981_2 1379698.RBG1_1C00001G1856 0.000107 50.4 COG3746@1|root,COG3746@2|Bacteria,2NRQ1@2323|unclassified Bacteria 2|Bacteria P phosphate-selective porin O and P oprP - - ko:K07221 - - - - ko00000,ko02000 1.B.5.1 - - Porin_4,Porin_O_P k141_1088_1 1116375.VEJY3_02915 4.07e-108 325.0 COG1070@1|root,COG1070@2|Bacteria,1N51F@1224|Proteobacteria,1RQX6@1236|Gammaproteobacteria,1XWBF@135623|Vibrionales 135623|Vibrionales H FGGY family of carbohydrate kinases, N-terminal domain - - 2.7.1.5 ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 - R01902,R03014 RC00002,RC00017 ko00000,ko00001,ko01000 - - - FGGY_C,FGGY_N k141_24760_2 1116375.VEJY3_09625 1.8e-44 144.0 2B34I@1|root,31XNK@2|Bacteria,1QK5X@1224|Proteobacteria,1TI94@1236|Gammaproteobacteria,1XYP5@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_24760_3 1190603.AJYD01000036_gene3810 1.89e-51 163.0 2EC5M@1|root,3364A@2|Bacteria,1NF9A@1224|Proteobacteria,1SFDF@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_24760_4 1278307.KB907036_gene630 1.29e-60 192.0 29W5V@1|root,30HQZ@2|Bacteria,1RFZX@1224|Proteobacteria,1S4QF@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - DUF4184,YdjM k141_9466_2 1219065.VPR01S_01_02990 2.27e-231 646.0 COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,1RMYY@1236|Gammaproteobacteria,1XWB0@135623|Vibrionales 135623|Vibrionales M Mechanosensitive ion channel - - - - - - - - - - - - MS_channel,MscS_TM k141_9466_3 223926.28807375 1.46e-189 531.0 COG1275@1|root,COG1275@2|Bacteria,1QMVH@1224|Proteobacteria,1RS7F@1236|Gammaproteobacteria,1XTQ2@135623|Vibrionales 135623|Vibrionales P COG1275 Tellurite resistance protein and related permeases - - - - - - - - - - - - SLAC1 k141_9466_4 1116375.VEJY3_12360 6.84e-113 330.0 COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,1RPT8@1236|Gammaproteobacteria,1XTXE@135623|Vibrionales 135623|Vibrionales K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_32989_1 1034347.CAHJ01000068_gene2529 6.28e-82 258.0 COG3263@1|root,COG3263@2|Bacteria,1TQPJ@1239|Firmicutes,4HC8I@91061|Bacilli,1ZC6H@1386|Bacillus 91061|Bacilli P COG3263 NhaP-type Na H and K H antiporters with a unique C-terminal domain nhaP - - ko:K11105 - - - - ko00000,ko02000 2.A.36.6 - - Na_H_Exchanger,TrkA_C k141_35551_1 1219072.VHA01S_080_00020 3.21e-08 57.8 COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,1RMAQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Transposase - - - - - - - - - - - - DEDD_Tnp_IS110,Transposase_20 k141_12993_1 984892.SPSE_1051 9.24e-39 134.0 COG0073@1|root,COG0073@2|Bacteria,1V3R1@1239|Firmicutes,4HHBI@91061|Bacilli,4GX8J@90964|Staphylococcaceae 91061|Bacilli J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily ytpR GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 - ko:K06878 - - - - ko00000 - - - DUF4479,tRNA_bind k141_1106_1 1453501.JELR01000001_gene2216 1e-13 81.3 COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,1RMDS@1236|Gammaproteobacteria,464FV@72275|Alteromonadaceae 1236|Gammaproteobacteria J Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs rne - 3.1.26.12 ko:K08300 ko03018,map03018 M00394 - - ko00000,ko00001,ko00002,ko01000,ko03009,ko03019 - - - RNase_E_G,S1 k141_2013_1 1279017.AQYJ01000026_gene203 2.05e-181 516.0 COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,1RMQI@1236|Gammaproteobacteria,464VE@72275|Alteromonadaceae 1236|Gammaproteobacteria K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth - - - - - - - - - - - - Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 k141_22484_1 1246484.D479_12803 5.24e-69 213.0 COG3601@1|root,COG3601@2|Bacteria,1V4BW@1239|Firmicutes,4HHFT@91061|Bacilli,3NE2B@45667|Halobacillus 91061|Bacilli U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins ribU GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656 - - - - - - - - - - ECF_trnsprt k141_10496_1 223926.28807466 1.28e-161 464.0 COG2027@1|root,COG2027@2|Bacteria,1MW40@1224|Proteobacteria,1RP8V@1236|Gammaproteobacteria,1XUAV@135623|Vibrionales 135623|Vibrionales M COG2027 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) dacB - 3.4.16.4 ko:K07259 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - Peptidase_S13 k141_10496_2 1280001.BAOA01000059_gene2289 1.94e-132 384.0 COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,1RPKC@1236|Gammaproteobacteria,1XVI5@135623|Vibrionales 135623|Vibrionales J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) tyrS GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006437,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - S4,tRNA-synt_1b k141_35552_1 1453501.JELR01000001_gene2465 1.04e-46 153.0 COG2050@1|root,COG2050@2|Bacteria,1N5HF@1224|Proteobacteria,1RNAK@1236|Gammaproteobacteria,46DIT@72275|Alteromonadaceae 1236|Gammaproteobacteria Q protein, possibly involved in aromatic compounds catabolism yigI GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - - - - - - - - - - 4HBT k141_21024_1 218284.CCDN010000006_gene3616 6.1e-172 484.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,4H9NS@91061|Bacilli,1ZCF9@1386|Bacillus 91061|Bacilli G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family gapA GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042866,GO:0043436,GO:0043891,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N k141_4451_1 223926.28808583 1.03e-18 86.3 COG4886@1|root,COG4886@2|Bacteria,1NF8D@1224|Proteobacteria,1SYIT@1236|Gammaproteobacteria,1XT24@135623|Vibrionales 135623|Vibrionales S Leucine-rich repeat (LRR) protein - - - - - - - - - - - - - k141_4451_2 223926.28808584 8.63e-39 131.0 2EGG2@1|root,33A83@2|Bacteria,1NHI2@1224|Proteobacteria,1SHG4@1236|Gammaproteobacteria,1XZ0C@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF1496) - - - - - - - - - - - - DUF1496 k141_4451_3 1116375.VEJY3_22421 2.44e-53 168.0 COG3691@1|root,COG3691@2|Bacteria,1NNR5@1224|Proteobacteria,1SHHC@1236|Gammaproteobacteria,1XYHA@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria VPA0419 - - - - - - - - - - - DUF406 k141_4451_4 223926.28808586 7.76e-96 280.0 COG1309@1|root,COG1309@2|Bacteria,1P117@1224|Proteobacteria,1SIAW@1236|Gammaproteobacteria,1XWYZ@135623|Vibrionales 135623|Vibrionales K Transcriptional regulator luxT - - - - - - - - - - - TetR_N k141_4451_5 1280001.BAOA01000026_gene5080 2.3e-161 454.0 COG4559@1|root,COG4559@2|Bacteria,1RD7N@1224|Proteobacteria,1RPUV@1236|Gammaproteobacteria,1XT9Z@135623|Vibrionales 135623|Vibrionales P Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system hmuV GO:0000041,GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006812,GO:0006826,GO:0008150,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0030001,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085 3.6.3.34 ko:K02013 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 - - ABC_tran k141_4451_6 1219076.N646_3087 8.12e-209 582.0 COG0609@1|root,COG0609@2|Bacteria,1MV9W@1224|Proteobacteria,1RMDF@1236|Gammaproteobacteria,1XSCG@135623|Vibrionales 135623|Vibrionales P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily hmuU - - ko:K02015 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - FecCD k141_4451_7 1280001.BAOA01000026_gene5078 2.84e-151 431.0 COG4558@1|root,COG4558@2|Bacteria,1QTSV@1224|Proteobacteria,1RNCT@1236|Gammaproteobacteria,1XTQ8@135623|Vibrionales 135623|Vibrionales P COG4558 ABC-type hemin transport system, periplasmic component huvB - - ko:K02016 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - Peripla_BP_2 k141_4451_8 1280001.BAOA01000026_gene5077 2.59e-75 227.0 COG0848@1|root,COG0848@2|Bacteria,1ND5E@1224|Proteobacteria,1SG8B@1236|Gammaproteobacteria,1XXBE@135623|Vibrionales 135623|Vibrionales U Biopolymer transport protein ExbD/TolR exbD1 GO:0003674,GO:0005215 - - - - - - - - - - ExbD k141_4451_9 674977.VMC_16020 3.63e-135 386.0 COG0811@1|root,COG0811@2|Bacteria,1RKWW@1224|Proteobacteria,1S6BX@1236|Gammaproteobacteria,1XTHB@135623|Vibrionales 135623|Vibrionales U MotA/TolQ/ExbB proton channel family exbB1 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0017038,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - ko:K03561 - - - - ko00000,ko02000 1.A.30.2.1 - - MotA_ExbB k141_4451_10 1280001.BAOA01000026_gene5075 8.09e-94 283.0 COG0810@1|root,COG0810@2|Bacteria,1MZPX@1224|Proteobacteria,1SCVJ@1236|Gammaproteobacteria,1XX0N@135623|Vibrionales 135623|Vibrionales M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins tonB1 - - ko:K03832 - - - - ko00000,ko02000 2.C.1.1 - - TonB_C k141_4451_11 223926.28808593 3.56e-298 817.0 COG0635@1|root,COG0635@2|Bacteria,1NTDN@1224|Proteobacteria,1RPGS@1236|Gammaproteobacteria,1XSD6@135623|Vibrionales 135623|Vibrionales H coproporphyrinogen III oxidase hutW - 2.1.1.342 ko:K21936 - - R11700 - ko00000,ko01000 - - - Radical_SAM k141_4451_12 1280001.BAOA01000026_gene5073 3.56e-101 295.0 COG3721@1|root,COG3721@2|Bacteria,1RK6M@1224|Proteobacteria,1S8K0@1236|Gammaproteobacteria,1XX48@135623|Vibrionales 135623|Vibrionales P heme iron utilization protein hutX - - ko:K07227 - - - - ko00000 - - - ChuX_HutX k141_29472_1 1116375.VEJY3_21706 3.22e-42 148.0 COG1073@1|root,COG1073@2|Bacteria,1MUCD@1224|Proteobacteria,1RP4I@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Hydrolases of the alpha beta superfamily - - - ko:K06889 - - - - ko00000 - - - AXE1,Abhydrolase_1,BAAT_C,DLH,DUF1100,Hydrolase_4,Peptidase_S15,RMMBL k141_29472_2 1515746.HR45_03795 2.45e-154 449.0 COG0477@1|root,COG0477@2|Bacteria,1QU73@1224|Proteobacteria,1T1PE@1236|Gammaproteobacteria,2QDV8@267890|Shewanellaceae 1236|Gammaproteobacteria EGP Sugar (and other) transporter - - - - - - - - - - - - MFS_1 k141_29472_3 1515746.HR45_03780 3.95e-137 392.0 COG1028@1|root,COG1028@2|Bacteria,1MW9A@1224|Proteobacteria,1RMMZ@1236|Gammaproteobacteria,2QAVV@267890|Shewanellaceae 1236|Gammaproteobacteria IQ KR domain - - 1.1.1.100,1.1.1.47 ko:K00034,ko:K00059 ko00030,ko00061,ko00333,ko00780,ko01040,ko01100,ko01120,ko01130,ko01200,ko01212,map00030,map00061,map00333,map00780,map01040,map01100,map01120,map01130,map01200,map01212 M00083,M00572 R01520,R01521,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00066,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 k141_29472_4 1353528.DT23_05420 2.09e-06 51.2 COG1846@1|root,COG1846@2|Bacteria,1PC0D@1224|Proteobacteria,2UIC7@28211|Alphaproteobacteria,2XNIT@285107|Thioclava 28211|Alphaproteobacteria K helix_turn_helix multiple antibiotic resistance protein - - - ko:K06075 - - - - ko00000,ko03000 - - - MarR,MarR_2 k141_16397_1 42565.FP66_06065 4.11e-152 437.0 COG1249@1|root,COG1249@2|Bacteria,1MVVE@1224|Proteobacteria,1RMJT@1236|Gammaproteobacteria,1XHMD@135619|Oceanospirillales 135619|Oceanospirillales C Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation sthA - 1.6.1.1 ko:K00322 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - Pyr_redox_2,Pyr_redox_dim k141_28088_1 1453501.JELR01000002_gene340 2.55e-117 347.0 COG3182@1|root,COG3182@2|Bacteria,1MW2S@1224|Proteobacteria,1RQYY@1236|Gammaproteobacteria,46CKU@72275|Alteromonadaceae 1236|Gammaproteobacteria S PepSY-associated TM region - - - - - - - - - - - - PepSY,PepSY_TM k141_5825_1 33035.JPJF01000031_gene2311 2.34e-05 52.0 COG3629@1|root,COG3899@1|root,COG3629@2|Bacteria,COG3899@2|Bacteria,1TR6V@1239|Firmicutes,24AA2@186801|Clostridia 186801|Clostridia T Bacterial transcriptional activator domain - - - - - - - - - - - - AAA_16,BTAD,TPR_12,Trans_reg_C k141_26093_1 1294265.JCM21738_1445 4.05e-102 296.0 COG1418@1|root,COG1418@2|Bacteria,1V3UK@1239|Firmicutes,4HH7I@91061|Bacilli,1ZFMK@1386|Bacillus 91061|Bacilli S phosphohydrolase yueE - - ko:K06950 - - - - ko00000 - - - HD k141_17464_1 1247024.JRLH01000006_gene2671 2.28e-16 71.2 2EK6X@1|root,33DXA@2|Bacteria,1NGFC@1224|Proteobacteria,1SH5J@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_3269_1 1517681.HW45_22490 6.31e-69 221.0 COG1706@1|root,COG1706@2|Bacteria,1MVKW@1224|Proteobacteria,1RMRB@1236|Gammaproteobacteria,1XUVU@135623|Vibrionales 135623|Vibrionales N Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation - - - ko:K02394 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FlgI k141_3269_2 1001585.MDS_0228 1.41e-07 58.5 COG0741@1|root,COG3951@1|root,COG0741@2|Bacteria,COG3951@2|Bacteria,1MV3F@1224|Proteobacteria,1SBNE@1236|Gammaproteobacteria,1YFN5@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria MNO Rod binding protein - - - ko:K08309 - - - - ko00000,ko01000,ko01011 - GH23 - Rod-binding,SLT k141_3269_3 1517681.HW45_22500 5.99e-116 355.0 COG1256@1|root,COG1256@2|Bacteria,1MV2M@1224|Proteobacteria,1RMEA@1236|Gammaproteobacteria,1XT20@135623|Vibrionales 135623|Vibrionales N flagellar hook-associated protein flgK - - ko:K02396 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C k141_3269_4 1123288.SOV_1c00210 6.76e-06 55.8 COG1344@1|root,COG1344@2|Bacteria,1TPDT@1239|Firmicutes,4H47I@909932|Negativicutes 909932|Negativicutes N Bacterial flagellin C-terminal helical region - - - ko:K02397 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flagellin_C,Flagellin_N k141_20071_1 511062.GU3_01175 6.89e-42 152.0 COG0213@1|root,COG0213@2|Bacteria,1MV3H@1224|Proteobacteria,1RPTG@1236|Gammaproteobacteria,1Y54S@135624|Aeromonadales 135624|Aeromonadales F Pyrimidine nucleoside phosphorylase C-terminal domain - - 2.4.2.4 ko:K00758 ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219 - R01570,R02484,R08222,R08230 RC00063 ko00000,ko00001,ko01000 - - - Glycos_trans_3N,Glycos_transf_3,PYNP_C k141_35553_1 218284.CCDN010000001_gene1264 1.72e-178 504.0 COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1TP4F@1239|Firmicutes,4HBNA@91061|Bacilli,1ZBTJ@1386|Bacillus 91061|Bacilli H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate ribD GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0016070,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 1.1.1.193,3.5.4.26 ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 M00125 R03458,R03459 RC00204,RC00933 ko00000,ko00001,ko00002,ko01000 - - - RibD_C,dCMP_cyt_deam_1 k141_22486_1 1042377.AFPJ01000029_gene552 1.86e-52 182.0 COG0642@1|root,COG2205@2|Bacteria,1N17V@1224|Proteobacteria,1RNFK@1236|Gammaproteobacteria,4647A@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0642 Signal transduction histidine kinase - - 2.7.13.3 ko:K07641 ko02020,map02020 M00449 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA k141_1108_1 218284.CCDN010000002_gene2952 2.22e-107 311.0 COG2096@1|root,COG2096@2|Bacteria,1V3PI@1239|Firmicutes,4HH26@91061|Bacilli,1ZCJ1@1386|Bacillus 91061|Bacilli S Adenosyltransferase yvqK - 2.5.1.17 ko:K00798 ko00860,ko01100,map00860,map01100 M00122 R01492,R05220,R07268 RC00533 ko00000,ko00001,ko00002,ko01000 - - - Cob_adeno_trans k141_28089_1 1033734.CAET01000078_gene3554 1.34e-110 323.0 COG0095@1|root,COG0095@2|Bacteria,1TQ5U@1239|Firmicutes,4HABG@91061|Bacilli,1ZBG2@1386|Bacillus 91061|Bacilli H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation lipM GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 6.3.1.20 ko:K03800 ko00785,ko01100,map00785,map01100 - R07770,R07771,R11143 RC00043,RC00070,RC00090,RC00992,RC02896 ko00000,ko00001,ko01000 - - - BPL_LplA_LipB k141_32991_1 1121035.AUCH01000006_gene680 2.92e-50 169.0 COG1057@1|root,COG1057@2|Bacteria,1RD0J@1224|Proteobacteria,2VSQ7@28216|Betaproteobacteria,2KW3W@206389|Rhodocyclales 206389|Rhodocyclales H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) nadD - 2.7.7.18 ko:K00969 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like k141_5827_1 1042377.AFPJ01000008_gene2002 1.84e-79 244.0 COG0119@1|root,COG0119@2|Bacteria,1MUMX@1224|Proteobacteria,1RMUX@1236|Gammaproteobacteria,469DW@72275|Alteromonadaceae 1236|Gammaproteobacteria E HMGL-like - - 4.1.3.4 ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 M00036,M00088 R01360,R08090 RC00502,RC00503,RC01118,RC01946 ko00000,ko00001,ko00002,ko01000 - - - HMGL-like k141_5827_2 1042377.AFPJ01000008_gene2003 6.66e-05 45.1 COG4704@1|root,COG4704@2|Bacteria,1N6RE@1224|Proteobacteria,1SGQS@1236|Gammaproteobacteria,46C17@72275|Alteromonadaceae 1236|Gammaproteobacteria S Uncharacterized protein conserved in bacteria (DUF2141) - - - - - - - - - - - - DUF2141 k141_21025_1 1078085.HMPREF1210_01538 2.33e-35 121.0 COG0695@1|root,COG0695@2|Bacteria,1VI6J@1239|Firmicutes,4IS2P@91061|Bacilli,26FXV@186818|Planococcaceae 91061|Bacilli O Glutaredoxin - - - - - - - - - - - - Glutaredoxin k141_15133_1 1453501.JELR01000002_gene1402 2.7e-135 389.0 COG2334@1|root,COG2334@2|Bacteria,1MU2Q@1224|Proteobacteria,1RNHI@1236|Gammaproteobacteria,464EM@72275|Alteromonadaceae 1236|Gammaproteobacteria F A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response srkA GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0071704,GO:0140096,GO:1901564 - - - - - - - - - - APH k141_35554_1 1379270.AUXF01000002_gene1793 4.44e-73 242.0 COG0480@1|root,COG0480@2|Bacteria,1ZTFA@142182|Gemmatimonadetes 142182|Gemmatimonadetes J Elongation factor G, domain IV - - - ko:K02355 - - - - ko00000,ko03012,ko03029 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU k141_4455_1 218284.CCDN010000001_gene1695 1.26e-126 387.0 COG0553@1|root,COG4715@1|root,COG0553@2|Bacteria,COG4715@2|Bacteria,1TPFZ@1239|Firmicutes,4HAIF@91061|Bacilli,1ZBZT@1386|Bacillus 91061|Bacilli L COG0553 Superfamily II DNA RNA helicases, SNF2 family snf - - - - - - - - - - - Helicase_C,SNF2_N,SNF2_assoc,SWIM k141_31580_3 1279017.AQYJ01000024_gene1012 1.2e-201 585.0 COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,1RQIX@1236|Gammaproteobacteria,4669Y@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0457 FOG TPR repeat - - - - - - - - - - - - TPR_14,TPR_16,TPR_19,TPR_2,TPR_6,TPR_8 k141_31580_4 1453501.JELR01000002_gene179 5.86e-78 240.0 COG3017@1|root,COG3017@2|Bacteria,1N02T@1224|Proteobacteria,1S91E@1236|Gammaproteobacteria,468AP@72275|Alteromonadaceae 1236|Gammaproteobacteria M Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein lolB GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006807,GO:0008104,GO:0008150,GO:0008152,GO:0008289,GO:0009279,GO:0010876,GO:0016020,GO:0019538,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0033218,GO:0034613,GO:0042157,GO:0042277,GO:0043170,GO:0044238,GO:0044462,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051641,GO:0051668,GO:0070727,GO:0071704,GO:0071723,GO:0071944,GO:0072657,GO:1901564 - ko:K02494 - - - - ko00000 - - - LolB k141_31580_5 1279017.AQYJ01000024_gene1010 6.47e-77 239.0 COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,1RP23@1236|Gammaproteobacteria,464HJ@72275|Alteromonadaceae 1236|Gammaproteobacteria I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol ispE GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006629,GO:0006720,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050515,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576 2.7.1.148 ko:K00919 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05634 RC00002,RC01439 ko00000,ko00001,ko00002,ko01000 - - iEC55989_1330.EC55989_1304 GHMP_kinases_C,GHMP_kinases_N k141_9470_2 498848.TaqDRAFT_4855 2.3e-28 109.0 COG0801@1|root,COG0801@2|Bacteria,1WJU9@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus H TIGRFAM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase folK - 2.7.6.3 ko:K00950 ko00790,ko01100,map00790,map01100 M00126,M00841 R03503 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - HPPK k141_2016_1 1453501.JELR01000001_gene1960 7.2e-95 283.0 COG1280@1|root,COG1280@2|Bacteria,1Q4CV@1224|Proteobacteria,1RQV8@1236|Gammaproteobacteria,466TI@72275|Alteromonadaceae 1236|Gammaproteobacteria E Lysine exporter protein (LysE YggA) - - - ko:K05834 - - - - ko00000,ko02000 2.A.76.1.1 - - LysE k141_34265_1 1116375.VEJY3_17706 8.2e-183 514.0 COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria,1N6EM@1224|Proteobacteria,1SBXG@1236|Gammaproteobacteria,1XU00@135623|Vibrionales 135623|Vibrionales M Belongs to the ompA family - - - ko:K03286 - - - - ko00000,ko02000 1.B.6 - - OMP_b-brl,OmpA,OmpA_membrane k141_34265_2 1280001.BAOA01000136_gene1955 3.33e-171 482.0 COG0722@1|root,COG0722@2|Bacteria,1MU5Q@1224|Proteobacteria,1RMAA@1236|Gammaproteobacteria,1XSHG@135623|Vibrionales 135623|Vibrionales E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) aroG - 2.5.1.54 ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 - - - DAHP_synth_1 k141_26095_1 1499680.CCFE01000015_gene963 4.84e-100 307.0 COG1032@1|root,COG1032@2|Bacteria,1UZQC@1239|Firmicutes,4IJPR@91061|Bacilli,1ZD7I@1386|Bacillus 91061|Bacilli C B12 binding domain - - - - - - - - - - - - B12-binding,Radical_SAM k141_3270_1 754035.Mesau_00635 4.17e-30 128.0 COG3468@1|root,COG3468@2|Bacteria,1R8WV@1224|Proteobacteria,2V8W0@28211|Alphaproteobacteria,43MM0@69277|Phyllobacteriaceae 28211|Alphaproteobacteria MU outer membrane autotransporter barrel domain - - - - - - - - - - - - Autotransporter k141_28090_1 1294265.JCM21738_1350 2.11e-102 307.0 COG2056@1|root,COG2056@2|Bacteria,1TSRY@1239|Firmicutes,4HBK6@91061|Bacilli,1ZB9I@1386|Bacillus 91061|Bacilli S antiporter yuiF - - ko:K07084 - - - - ko00000,ko02000 2.A.8.1.12 - iSB619.SA_RS04585 Na_H_antiport_2,Na_H_antiporter k141_22488_1 935836.JAEL01000003_gene363 5.18e-172 511.0 COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,4HAFP@91061|Bacilli,1ZBJ3@1386|Bacillus 91061|Bacilli V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family swrC - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran k141_32993_1 218284.CCDN010000002_gene2875 1.76e-99 302.0 COG1053@1|root,COG1053@2|Bacteria,1TPAR@1239|Firmicutes,4HAXN@91061|Bacilli,1ZBU7@1386|Bacillus 91061|Bacilli C COG1053 Succinate dehydrogenase fumarate reductase, flavoprotein subunit - - - ko:K13796 - - - - ko00000 - - - FAD_binding_2 k141_17465_2 1122194.AUHU01000003_gene2124 3.37e-35 125.0 COG3682@1|root,COG3682@2|Bacteria,1N03Y@1224|Proteobacteria,1SBVR@1236|Gammaproteobacteria,467YD@72275|Alteromonadaceae 1236|Gammaproteobacteria K Penicillinase repressor - - - - - - - - - - - - Penicillinase_R k141_17465_3 1298865.H978DRAFT_3933 3.53e-161 465.0 COG2234@1|root,COG2234@2|Bacteria,1MWBX@1224|Proteobacteria,1RYHQ@1236|Gammaproteobacteria,465S8@72275|Alteromonadaceae 1236|Gammaproteobacteria S Fibronectin type 3 domain - - - - - - - - - - - - Peptidase_M28,fn3 k141_15134_2 1379270.AUXF01000006_gene312 1.05e-54 182.0 COG2199@1|root,COG2199@2|Bacteria,1ZT1F@142182|Gemmatimonadetes 142182|Gemmatimonadetes T Diguanylate cyclase, GGDEF domain - - - - - - - - - - - - GGDEF k141_11861_1 1280001.BAOA01000021_gene746 0.0 1211.0 COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,1RPZ7@1236|Gammaproteobacteria,1XT0R@135623|Vibrionales 135623|Vibrionales L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA priA - - ko:K04066 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C k141_17507_1 218284.CCDN010000004_gene3126 7.22e-96 293.0 COG1288@1|root,COG1288@2|Bacteria,1TQJ0@1239|Firmicutes,4H9P7@91061|Bacilli,1ZBC6@1386|Bacillus 91061|Bacilli S Membrane ycgA - - - - - - - - - - - DcuC k141_24797_1 218284.CCDN010000005_gene3354 6.37e-132 383.0 COG3320@1|root,COG3320@2|Bacteria,1TQPW@1239|Firmicutes,4HAFC@91061|Bacilli,1ZCU0@1386|Bacillus 91061|Bacilli Q Male sterility protein - - - - - - - - - - - - NAD_binding_4 k141_5859_1 218284.CCDN010000003_gene3011 7.37e-104 308.0 COG0115@1|root,COG0115@2|Bacteria,1TSIP@1239|Firmicutes,4HC7K@91061|Bacilli,1ZCRC@1386|Bacillus 91061|Bacilli EH 4-amino-4-deoxychorismate lyase pabC - 4.1.3.38 ko:K02619 ko00790,map00790 - R05553 RC01843,RC02148 ko00000,ko00001,ko01000 - - - Aminotran_4 k141_1132_1 796606.BMMGA3_12765 1.03e-97 301.0 COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,4H9VR@91061|Bacilli,1ZB1D@1386|Bacillus 91061|Bacilli E Acetolactate synthase ilvB - 2.2.1.6 ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 M00019,M00570,M00582 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - iYO844.BSU28310 TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N k141_34283_1 1453501.JELR01000002_gene117 7.52e-90 273.0 COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RNXA@1236|Gammaproteobacteria,465VR@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0436 Aspartate tyrosine aromatic aminotransferase - - 4.1.1.82 ko:K09459,ko:K10907 ko00440,ko01100,ko01120,ko01130,map00440,map01100,map01120,map01130 - R04053 RC00506 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 k141_4502_1 1279017.AQYJ01000025_gene489 5.39e-179 518.0 COG1328@1|root,COG1328@2|Bacteria,1MWMS@1224|Proteobacteria,1RZFM@1236|Gammaproteobacteria,46623@72275|Alteromonadaceae 1236|Gammaproteobacteria F COG1328 Oxygen-sensitive ribonucleoside-triphosphate reductase nrdD - 1.1.98.6 ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R11633,R11634,R11635,R11636 RC00613 ko00000,ko00001,ko00002,ko01000 - - - NRDD k141_9499_1 1116375.VEJY3_23681 5.84e-18 82.0 COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,1RMEN@1236|Gammaproteobacteria,1XU7P@135623|Vibrionales 135623|Vibrionales U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - - - - - - - - - - SDF k141_9499_3 223926.28810018 4.89e-121 364.0 COG0366@1|root,COG0366@2|Bacteria,1MU90@1224|Proteobacteria,1RQ1S@1236|Gammaproteobacteria,1XURK@135623|Vibrionales 135623|Vibrionales G alpha-amylase malS - 3.2.1.1 ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 - R02108,R02112,R11262 - ko00000,ko00001,ko01000 - GH13 - Alpha-amylase k141_19911_1 218284.CCDN010000001_gene302 1.94e-24 99.4 2C6AM@1|root,2ZUPR@2|Bacteria,1W6NY@1239|Firmicutes,4I0NT@91061|Bacilli,1ZIZT@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF4367) - - - - - - - - - - - - DUF4367 k141_4356_1 565045.NOR51B_927 8.07e-73 235.0 COG3949@1|root,COG3949@2|Bacteria,1QAYU@1224|Proteobacteria 1224|Proteobacteria S Membrane - - - - - - - - - - - - - k141_14213_1 218284.CCDN010000001_gene556 1.63e-251 712.0 COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,4H9NZ@91061|Bacilli,1ZBJV@1386|Bacillus 91061|Bacilli L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity mutS2 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K07456 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_V,Smr k141_17382_1 1453501.JELR01000002_gene783 4.01e-192 561.0 COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,1RQEX@1236|Gammaproteobacteria,463Z7@72275|Alteromonadaceae 1236|Gammaproteobacteria M Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane lptD GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0009279,GO:0009636,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0042221,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0050896,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:1901264 - ko:K04744 - - - - ko00000,ko02000 1.B.42.1 - iG2583_1286.G2583_0058 OstA,OstA_C k141_17382_2 1453501.JELR01000002_gene782 7.07e-189 533.0 COG3178@1|root,COG3178@2|Bacteria,1MXCH@1224|Proteobacteria,1RQ1Q@1236|Gammaproteobacteria,466NT@72275|Alteromonadaceae 1236|Gammaproteobacteria S phosphotransferase related to Ser Thr protein kinases - GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006022,GO:0006040,GO:0006082,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 2.7.1.221 ko:K07102 ko00520,ko01100,map00520,map01100 - R08968,R11024 RC00002,RC00078 ko00000,ko00001,ko01000 - - - APH k141_17382_3 1279017.AQYJ01000020_gene1241 1.2e-132 380.0 COG1208@1|root,COG1208@2|Bacteria,1R9ZD@1224|Proteobacteria,1S23A@1236|Gammaproteobacteria,466S9@72275|Alteromonadaceae 1236|Gammaproteobacteria JM COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon) - GO:0000166,GO:0000270,GO:0000287,GO:0001882,GO:0001884,GO:0002134,GO:0003674,GO:0003824,GO:0005488,GO:0006022,GO:0006040,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0019103,GO:0019752,GO:0030203,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044281,GO:0046872,GO:0070569,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 2.7.7.13,2.7.7.99 ko:K00966,ko:K00992 ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110 M00114,M00361,M00362 R00885,R11025 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase k141_17382_8 1279017.AQYJ01000020_gene1235 4.61e-180 509.0 COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,1RNXV@1236|Gammaproteobacteria,4661X@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) trpD GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 ko:K00766 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R01073 RC00440 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_0421 Glycos_trans_3N,Glycos_transf_3 k141_17382_9 1279017.AQYJ01000020_gene1234 2.9e-150 427.0 COG0134@1|root,COG0134@2|Bacteria,1MW5K@1224|Proteobacteria,1RNYH@1236|Gammaproteobacteria,464E7@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the TrpC family trpC GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48,5.3.1.24 ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03508,R03509 RC00944,RC00945 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_0422 IGPS k141_17382_10 394221.Mmar10_1051 8.08e-70 230.0 COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,2TSGE@28211|Alphaproteobacteria,43WYA@69657|Hyphomonadaceae 28211|Alphaproteobacteria S COG0457 FOG TPR repeat - - - - - - - - - - - - Sulfotransfer_3,TPR_16,TPR_2,TPR_8 k141_27955_5 634956.Geoth_0761 1.12e-151 444.0 COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,4H9Y8@91061|Bacilli,1WFN6@129337|Geobacillus 91061|Bacilli L Participates in initiation and elongation during chromosome replication - - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k141_27955_6 420246.GTNG_2866 1.16e-43 161.0 COG3935@1|root,COG3935@2|Bacteria,1VB3X@1239|Firmicutes,4IQUK@91061|Bacilli,1WG4Q@129337|Geobacillus 91061|Bacilli L Replication initiation and membrane attachment - - - - - - - - - - - - DnaB_2 k141_12882_1 218284.CCDN010000004_gene3109 1.77e-71 223.0 COG4989@1|root,COG4989@2|Bacteria,1TQ12@1239|Firmicutes,4HA57@91061|Bacilli,1ZD8D@1386|Bacillus 91061|Bacilli S Oxidoreductase ycsN - - - - - - - - - - - Aldo_ket_red k141_12882_3 1131730.BAVI_06834 1.59e-32 114.0 2EURH@1|root,333HF@2|Bacteria,1VEGJ@1239|Firmicutes,4HP3K@91061|Bacilli,1ZR8B@1386|Bacillus 91061|Bacilli S Transcriptional regulator protein (SplA) - - - ko:K06315 - - - - ko00000,ko03000 - - - SplA k141_12882_4 218284.CCDN010000004_gene3117 3.06e-81 248.0 COG1533@1|root,COG1533@2|Bacteria,1TPA3@1239|Firmicutes,4HACB@91061|Bacilli,1ZBPU@1386|Bacillus 91061|Bacilli L Spore photoproduct lyase splB GO:0003674,GO:0003824,GO:0003913,GO:0005488,GO:0005575,GO:0005623,GO:0016829,GO:0016830,GO:0042601,GO:0042763,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0070283,GO:0140097 4.1.99.14 ko:K03716 - - - - ko00000,ko01000 - - - - k141_3144_1 218284.CCDN010000002_gene2137 1.23e-37 130.0 COG1878@1|root,COG1878@2|Bacteria,1U801@1239|Firmicutes,4HDQ3@91061|Bacilli,1ZD77@1386|Bacillus 91061|Bacilli S Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation kynB - 3.5.1.9 ko:K07130 ko00380,ko00630,ko01100,map00380,map00630,map01100 M00038 R00988,R01959,R04911 RC00263,RC00323 ko00000,ko00001,ko00002,ko01000 - - - Cyclase k141_20929_1 218284.CCDN010000004_gene3041 5.52e-163 461.0 COG4294@1|root,COG4294@2|Bacteria,1TTCB@1239|Firmicutes,4H9PY@91061|Bacilli,1ZCJ7@1386|Bacillus 91061|Bacilli L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion uvsE - - ko:K13281 - - - - ko00000,ko01000 - - - UvdE k141_23636_1 1121091.AUMP01000003_gene2579 3.12e-48 159.0 COG3677@1|root,COG3677@2|Bacteria,1V8R5@1239|Firmicutes,4HJMG@91061|Bacilli 91061|Bacilli L Transposase yqaQ - - - - - - - - - - - GerE,HTH_28 k141_23636_2 1354300.AUQY01000005_gene131 8.75e-10 59.7 COG2131@1|root,COG2131@2|Bacteria,1V3PU@1239|Firmicutes,24HF0@186801|Clostridia,22H7K@1570339|Peptoniphilaceae 186801|Clostridia F ComE operon protein 2 comEB - 3.5.4.12 ko:K01493 ko00240,ko01100,map00240,map01100 M00429 R01663 RC00074 ko00000,ko00001,ko00002,ko01000,ko02044 - - - dCMP_cyt_deam_1 k141_23636_9 1234664.AMRO01000024_gene1796 3.83e-62 196.0 2DM82@1|root,324KK@2|Bacteria,1V9IJ@1239|Firmicutes,4HJEV@91061|Bacilli,1WGSK@129337|Geobacillus 91061|Bacilli - - - - 3.1.22.4 ko:K01159 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - - k141_23636_11 1232666.JANE01000070_gene1288 2.25e-26 101.0 COG1694@1|root,COG1694@2|Bacteria,1VIQA@1239|Firmicutes,4HM6C@91061|Bacilli,4GZGM@90964|Staphylococcaceae 91061|Bacilli S MazG nucleotide pyrophosphohydrolase domain - - - - - - - - - - - - MazG k141_22295_2 1294265.JCM21738_1461 5.78e-36 135.0 COG5276@1|root,COG5276@2|Bacteria,1UUVN@1239|Firmicutes,4HBJX@91061|Bacilli,1ZE6M@1386|Bacillus 91061|Bacilli S LVIVD repeat - - - - - - - - - - - - LVIVD k141_29315_1 1279017.AQYJ01000028_gene2321 3.15e-134 434.0 COG2982@1|root,COG2982@2|Bacteria,1MUME@1224|Proteobacteria,1RNPC@1236|Gammaproteobacteria,464KK@72275|Alteromonadaceae 1236|Gammaproteobacteria M Domain of Unknown Function (DUF748) - - - - - - - - - - - - DUF748,OmpA k141_36329_1 218284.CCDN010000002_gene2755 2.65e-67 208.0 COG1335@1|root,COG1335@2|Bacteria,1V0RD@1239|Firmicutes,4HD8Z@91061|Bacilli,1ZFUY@1386|Bacillus 91061|Bacilli Q isochorismatase - - - - - - - - - - - - Isochorismatase k141_947_1 935837.JAEK01000030_gene2708 1.81e-67 209.0 COG1999@1|root,COG1999@2|Bacteria,1V03J@1239|Firmicutes,4HET3@91061|Bacilli,1ZFJQ@1386|Bacillus 91061|Bacilli S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems - - - ko:K07152 - - - - ko00000,ko03029 - - - SCO1-SenC k141_37536_1 1294265.JCM21738_4865 7.13e-57 178.0 COG2344@1|root,COG2344@2|Bacteria,1TSMR@1239|Firmicutes,4HB7Q@91061|Bacilli,1ZANM@1386|Bacillus 91061|Bacilli K Modulates transcription in response to changes in cellular NADH NAD( ) redox state rex - - ko:K01926 - - - - ko00000,ko03000 - - - CoA_binding,Put_DNA-bind_N k141_37536_2 1294265.JCM21738_4864 3.63e-40 132.0 28VF7@1|root,2ZHHS@2|Bacteria,1W30J@1239|Firmicutes,4I07C@91061|Bacilli,1ZJ43@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF4305) - - - - - - - - - - - - DUF4305 k141_37536_3 1294265.JCM21738_4863 1.42e-55 179.0 COG1266@1|root,COG1266@2|Bacteria,1V7N7@1239|Firmicutes,4HI4E@91061|Bacilli,1ZRP1@1386|Bacillus 91061|Bacilli S metal-dependent membrane protease ydiL - - ko:K07052 - - - - ko00000 - - - Abi k141_6874_2 1219072.VHA01S_013_00090 3.35e-65 199.0 2DNNV@1|root,32YCB@2|Bacteria,1N7IN@1224|Proteobacteria,1S9V9@1236|Gammaproteobacteria,1XXWX@135623|Vibrionales 135623|Vibrionales S CcdB protein - - - ko:K19163 - - - - ko00000,ko02048 - - - CcdB k141_6874_3 29495.EA26_14710 5.98e-48 153.0 COG5302@1|root,COG5302@2|Bacteria,1NIFA@1224|Proteobacteria,1SD2V@1236|Gammaproteobacteria,1XYNH@135623|Vibrionales 135623|Vibrionales S Post-segregation antitoxin CcdA - - - ko:K19164 - - - - ko00000,ko02048 - - - CcdA k141_6874_4 1219076.N646_0809 5.35e-82 243.0 2APBA@1|root,31EDH@2|Bacteria,1RIDJ@1224|Proteobacteria,1S6VZ@1236|Gammaproteobacteria,1XXQ8@135623|Vibrionales 135623|Vibrionales S Putative prokaryotic signal transducing protein - - - - - - - - - - - - DUF2007 k141_27319_1 1033743.CAES01000078_gene3761 1.55e-14 72.0 COG0500@1|root,COG2226@2|Bacteria,1UYID@1239|Firmicutes,4HAJE@91061|Bacilli,26UBK@186822|Paenibacillaceae 91061|Bacilli Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_25 k141_27319_2 315730.BcerKBAB4_5497 1.01e-15 81.6 COG1073@1|root,COG1073@2|Bacteria,1TSFY@1239|Firmicutes,4HDNK@91061|Bacilli,1ZCJW@1386|Bacillus 91061|Bacilli G Serine aminopeptidase, S33 - - - ko:K06889 - - - - ko00000 - - - Abhydrolase_6,Cu_amine_oxidN1,DUF3887,Hydrolase_4,Peptidase_S9,SLH k141_23637_1 218284.CCDN010000001_gene1070 6.01e-123 360.0 COG4955@1|root,COG4955@2|Bacteria,1TQU9@1239|Firmicutes,4HFUR@91061|Bacilli,1ZDGR@1386|Bacillus 91061|Bacilli S protein conserved in bacteria ypbB - 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 - - - HTH_40,RQC k141_3145_1 1294265.JCM21738_4578 1.3e-47 153.0 2E9CH@1|root,333K6@2|Bacteria,1VG2H@1239|Firmicutes,4HNZC@91061|Bacilli,1ZIUF@1386|Bacillus 91061|Bacilli S Sigma-K factor-processing regulatory protein BofA bofA - - ko:K06317 - - - - ko00000 - - - BofA k141_29316_1 797299.HALLA_01725 5.28e-29 119.0 COG1651@1|root,COG2116@1|root,arCOG02868@2157|Archaea,arCOG03454@2157|Archaea,2XW8R@28890|Euryarchaeota,23U3Q@183963|Halobacteria 183963|Halobacteria OP DSBA-like thioredoxin domain - - - ko:K21990 - - - - ko00000 1.A.16.4 - - Form_Nir_trans,Thioredoxin_4 k141_22296_1 218284.CCDN010000008_gene4165 5.03e-67 204.0 2CESQ@1|root,34AAA@2|Bacteria,1VYVE@1239|Firmicutes,4HY3F@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - k141_22296_2 1121121.KB894319_gene3812 2.92e-34 125.0 COG3142@1|root,COG3142@2|Bacteria,1UYI8@1239|Firmicutes,4IR0G@91061|Bacilli,26UKD@186822|Paenibacillaceae 91061|Bacilli P Participates in the control of copper homeostasis cutC - - ko:K06201 - - - - ko00000 - - - CutC k141_4358_1 1145276.T479_08530 8.29e-26 96.7 2DQ3R@1|root,334M1@2|Bacteria,1U8R1@1239|Firmicutes,4IIP1@91061|Bacilli,3IYT5@400634|Lysinibacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_18907_2 218284.CCDN010000001_gene366 9.57e-64 203.0 COG1172@1|root,COG1172@2|Bacteria,1TP72@1239|Firmicutes,4H9Y3@91061|Bacilli,1ZBAZ@1386|Bacillus 91061|Bacilli G Belongs to the binding-protein-dependent transport system permease family rbsC GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015749,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0034219,GO:0044425,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 - ko:K10440 ko02010,map02010 M00212 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - BPD_transp_2 k141_19912_1 218284.CCDN010000001_gene1723 3.5e-17 80.5 COG1075@1|root,COG1075@2|Bacteria,1TQFF@1239|Firmicutes,4HDQN@91061|Bacilli,1ZCCU@1386|Bacillus 91061|Bacilli S acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - - - - - - - - - - PGAP1 k141_19912_2 218284.CCDN010000001_gene1722 9.57e-226 625.0 COG2866@1|root,COG2866@2|Bacteria,1UR6S@1239|Firmicutes,4HAPV@91061|Bacilli,1ZDU8@1386|Bacillus 91061|Bacilli E Zn_pept - - - ko:K06987 - - - - ko00000 - - - Peptidase_M14 k141_37537_1 42565.FP66_08895 7.42e-80 242.0 COG0561@1|root,COG0561@2|Bacteria,1MV02@1224|Proteobacteria,1RP1D@1236|Gammaproteobacteria,1XMW4@135619|Oceanospirillales 135619|Oceanospirillales S Sucrose-6F-phosphate phosphohydrolase - - - - - - - - - - - - Hydrolase_3 k141_16266_1 218284.CCDN010000001_gene53 2.1e-183 524.0 COG1293@1|root,COG1293@2|Bacteria,1TQ8A@1239|Firmicutes,4H9UF@91061|Bacilli,1ZBGD@1386|Bacillus 91061|Bacilli K RNA-binding protein homologous to eukaryotic snRNP FbpA - - - - - - - - - - - DUF814,FbpA k141_16266_2 218284.CCDN010000001_gene54 7.13e-116 335.0 COG0461@1|root,COG0461@2|Bacteria,1V1BZ@1239|Firmicutes,4HFV7@91061|Bacilli,1ZASD@1386|Bacillus 91061|Bacilli F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) pyrE - 2.4.2.10 ko:K00762 ko00240,ko01100,map00240,map01100 M00051 R01870 RC00611 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU15560 Pribosyltran k141_35396_2 1042377.AFPJ01000019_gene2549 2.57e-299 823.0 COG2195@1|root,COG2195@2|Bacteria,1MUWK@1224|Proteobacteria,1RP5F@1236|Gammaproteobacteria,4669W@72275|Alteromonadaceae 1236|Gammaproteobacteria E Peptidase family M20/M25/M40 pepD GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0009056,GO:0009987,GO:0016787,GO:0016805,GO:0019538,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0070573,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - ko:K01270 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - iPC815.YPO3230,iSBO_1134.SBO_0243 M20_dimer,Peptidase_M20 k141_35396_3 1279017.AQYJ01000026_gene230 6.63e-213 607.0 COG4776@1|root,COG4776@2|Bacteria,1P563@1224|Proteobacteria,1RP5G@1236|Gammaproteobacteria,46DF9@72275|Alteromonadaceae 1236|Gammaproteobacteria K RNB rnb GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0008859,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360,GO:1901361,GO:1901575 3.1.13.1 ko:K01147 - - - - ko00000,ko01000,ko03016 - - - OB_RNB,RNB,S1 k141_32828_2 1415778.JQMM01000001_gene1 2e-05 45.4 COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,1RN6K@1236|Gammaproteobacteria,1J56P@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) aceE - 1.2.4.1 ko:K00163 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_0339 Transketolase_N k141_34140_1 1127673.GLIP_3420 1.53e-73 242.0 COG4232@1|root,COG4233@1|root,COG4232@2|Bacteria,COG4233@2|Bacteria,1MU8W@1224|Proteobacteria,1RPF7@1236|Gammaproteobacteria,46550@72275|Alteromonadaceae 1236|Gammaproteobacteria CO Thiol disulfide interchange protein - - 1.8.1.8 ko:K04084 - - - - ko00000,ko01000,ko03110 5.A.1.1 - - DsbC,DsbD,Thioredoxin_7 k141_34140_2 1279017.AQYJ01000023_gene3147 4.96e-114 332.0 COG1720@1|root,COG1720@2|Bacteria,1MUF0@1224|Proteobacteria,1RPCX@1236|Gammaproteobacteria,466V7@72275|Alteromonadaceae 1236|Gammaproteobacteria S Uncharacterised protein family UPF0066 yaeB GO:0000049,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016426,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0089715,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363 - - - - - - - - - - UPF0066 k141_22297_1 42565.FP66_05705 5.14e-89 262.0 COG0589@1|root,COG0589@2|Bacteria,1RHE6@1224|Proteobacteria,1S6AR@1236|Gammaproteobacteria,1XK8T@135619|Oceanospirillales 135619|Oceanospirillales T Universal stress protein uspA - - ko:K06149 - - - - ko00000 - - - Usp k141_17383_1 218284.CCDN010000007_gene3804 1.67e-25 101.0 COG0668@1|root,COG0668@2|Bacteria,1TR9Z@1239|Firmicutes,4HCB8@91061|Bacilli,1ZCW4@1386|Bacillus 91061|Bacilli M Mechanosensitive ion channel ykuT - - ko:K22044 - - - - ko00000,ko02000 1.A.23.3 - - MS_channel k141_17383_2 218284.CCDN010000007_gene3805 2.26e-43 140.0 COG4481@1|root,COG4481@2|Bacteria,1VEQ7@1239|Firmicutes,4HNHU@91061|Bacilli,1ZIUV@1386|Bacillus 91061|Bacilli S protein conserved in bacteria yyzM - - - - - - - - - - - DUF951 k141_18908_2 394503.Ccel_1290 4.57e-23 96.7 COG0235@1|root,COG0235@2|Bacteria,1TS5G@1239|Firmicutes,248NY@186801|Clostridia,36H4D@31979|Clostridiaceae 186801|Clostridia G Class II aldolase - - 4.1.2.17 ko:K01628 ko00051,ko01120,map00051,map01120 - R02262 RC00603,RC00604 ko00000,ko00001,ko01000 - - - Aldolase_II k141_6876_1 1285586.H131_21627 4.73e-41 145.0 COG0451@1|root,COG0451@2|Bacteria,1TQSN@1239|Firmicutes,4HBXX@91061|Bacilli,3IZ2H@400634|Lysinibacillus 91061|Bacilli GM NmrA-like family - - - - - - - - - - - - Epimerase,NAD_binding_10 k141_5712_2 1279017.AQYJ01000028_gene2416 0.0 886.0 COG2873@1|root,COG2873@2|Bacteria,1R3QG@1224|Proteobacteria,1RNSA@1236|Gammaproteobacteria,46648@72275|Alteromonadaceae 1236|Gammaproteobacteria E Cys/Met metabolism PLP-dependent enzyme - - - - - - - - - - - - Cys_Met_Meta_PP k141_5712_3 1279017.AQYJ01000028_gene2415 1.29e-225 630.0 COG0265@1|root,COG0265@2|Bacteria,1NXB0@1224|Proteobacteria,1RRAD@1236|Gammaproteobacteria,465AC@72275|Alteromonadaceae 1236|Gammaproteobacteria O Trypsin-like peptidase domain - - - - - - - - - - - - Trypsin_2 k141_5712_4 1279017.AQYJ01000028_gene2414 1.3e-114 343.0 COG1716@1|root,COG1716@2|Bacteria,1MXT7@1224|Proteobacteria,1SAKZ@1236|Gammaproteobacteria,468KA@72275|Alteromonadaceae 1236|Gammaproteobacteria T Forkhead associated domain - - - - - - - - - - - - FHA,Yop-YscD_cpl k141_5712_5 1042377.AFPJ01000024_gene689 3.11e-168 480.0 COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,1RP4T@1236|Gammaproteobacteria,464SK@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily hisC - 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k141_5712_6 991905.SL003B_3727 2.23e-66 216.0 COG3770@1|root,COG3770@2|Bacteria,1MU9I@1224|Proteobacteria,2TR3K@28211|Alphaproteobacteria,4BRVC@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria M Penicillin-insensitive murein endopeptidase mepA - - ko:K07261 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_M74 k141_29342_4 1453501.JELR01000002_gene1302 7.01e-89 269.0 COG3108@1|root,COG3108@2|Bacteria,1N3XU@1224|Proteobacteria,1SQF8@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Peptidase M15 - - - - - - - - - - - - Peptidase_M15_3 k141_6910_1 1294265.JCM21738_3689 2.17e-27 102.0 COG0712@1|root,COG0712@2|Bacteria,1VAG3@1239|Firmicutes,4HKFW@91061|Bacilli,1ZG65@1386|Bacillus 91061|Bacilli C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpH - - ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - OSCP k141_6910_2 1294265.JCM21738_3688 5.83e-78 237.0 COG0711@1|root,COG0711@2|Bacteria,1VB85@1239|Firmicutes,4HM64@91061|Bacilli,1ZGHN@1386|Bacillus 91061|Bacilli C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) atpF - - ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - iYO844.BSU36850 ATP-synt_B k141_17390_1 458817.Shal_1983 7.17e-254 726.0 2EXJW@1|root,33QVY@2|Bacteria,1QSMJ@1224|Proteobacteria,1SK5H@1236|Gammaproteobacteria,2QA2U@267890|Shewanellaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_14240_1 1196031.ALEG01000040_gene2946 2.45e-133 382.0 COG1521@1|root,COG1521@2|Bacteria,1TR0X@1239|Firmicutes,4H9QA@91061|Bacilli,1ZBQ0@1386|Bacillus 91061|Bacilli F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis coaX - 2.7.1.33 ko:K03525 ko00770,ko01100,map00770,map01100 M00120 R02971,R03018,R04391 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Pan_kinase k141_37558_1 1279017.AQYJ01000018_gene809 8.11e-76 226.0 COG1146@1|root,COG1146@2|Bacteria,1RH5I@1224|Proteobacteria,1S5ZK@1236|Gammaproteobacteria,467GP@72275|Alteromonadaceae 1236|Gammaproteobacteria C Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions fdxA - - ko:K05524 - - - - ko00000 - - - DUF3470,Fer4,Fer4_9 k141_35424_2 1453501.JELR01000002_gene202 1.3e-42 147.0 COG2971@1|root,COG2971@2|Bacteria,1R41I@1224|Proteobacteria,1RPMK@1236|Gammaproteobacteria,466SH@72275|Alteromonadaceae 1236|Gammaproteobacteria G BadF/BadG/BcrA/BcrD ATPase family gspK GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0047931 2.7.1.8 ko:K18676 ko00520,ko01100,map00520,map01100 - R01961 RC00002,RC00017 ko00000,ko00001,ko01000 - - - BcrAD_BadFG k141_20939_1 1049564.TevJSym_ah00480 2.36e-20 91.3 COG2265@1|root,COG2265@2|Bacteria,1MV3A@1224|Proteobacteria,1RN1D@1236|Gammaproteobacteria,1J5T0@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family rlmD GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0070041,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.190 ko:K03215 - - - - ko00000,ko01000,ko03009 - - - TRAM,tRNA_U5-meth_tr k141_14241_1 218284.CCDN010000001_gene599 8.52e-97 283.0 2CYGZ@1|root,32T47@2|Bacteria,1VA1R@1239|Firmicutes,4HM46@91061|Bacilli,1ZGJG@1386|Bacillus 91061|Bacilli - - ysxD - - - - - - - - - - - - k141_17391_1 1192034.CAP_3244 1.46e-35 125.0 COG3682@1|root,COG3682@2|Bacteria,1RKDI@1224|Proteobacteria,4383A@68525|delta/epsilon subdivisions,2X3DA@28221|Deltaproteobacteria,2YVI8@29|Myxococcales 28221|Deltaproteobacteria K Penicillinase repressor - - - - - - - - - - - - Penicillinase_R k141_17391_2 379066.GAU_0801 7.28e-07 52.4 COG1413@1|root,COG4219@1|root,COG1413@2|Bacteria,COG4219@2|Bacteria 2|Bacteria C deoxyhypusine monooxygenase activity - - - - - - - - - - - - HEAT_2,HEAT_PBS,Peptidase_M56 k141_34162_1 1132442.KB889752_gene1879 6.97e-48 160.0 COG4821@1|root,COG4821@2|Bacteria,1TQS7@1239|Firmicutes,4HCR4@91061|Bacilli,1ZAP1@1386|Bacillus 91061|Bacilli S carbohydrate derivative metabolic process - - - - - - - - - - - - SIS_2 k141_6912_1 218284.CCDN010000005_gene3347 8.06e-164 467.0 COG1972@1|root,COG1972@2|Bacteria,1TRSK@1239|Firmicutes,4HA8N@91061|Bacilli,1ZAW2@1386|Bacillus 91061|Bacilli F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family yutK GO:0003674,GO:0005215,GO:0005337,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0015858,GO:0015931,GO:0015932,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:1901264,GO:1901505,GO:1901642 - ko:K03317 - - - - ko00000 2.A.41 - iYO844.BSU32180 Gate,Nucleos_tra2_C,Nucleos_tra2_N k141_11694_1 223926.28805713 6.76e-274 768.0 COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,1RP14@1236|Gammaproteobacteria,1XTP8@135623|Vibrionales 135623|Vibrionales J Belongs to the class-I aminoacyl-tRNA synthetase family leuS - 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Anticodon_1,tRNA-synt_1,tRNA-synt_1_2 k141_11694_2 1116375.VEJY3_03350 1.45e-106 307.0 COG2888@1|root,COG2888@2|Bacteria,1P9T7@1224|Proteobacteria,1SAPZ@1236|Gammaproteobacteria,1XU0U@135623|Vibrionales 135623|Vibrionales J Zinc-ribbon containing domain - - - - - - - - - - - - DUF1451 k141_11694_3 1116375.VEJY3_03355 0.0 962.0 COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,1RM8M@1236|Gammaproteobacteria,1XSXY@135623|Vibrionales 135623|Vibrionales M Transfers the fatty acyl group on membrane lipoproteins lnt GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 - ko:K03820 - - - - ko00000,ko01000 - GT2 - CN_hydrolase k141_11694_4 1116375.VEJY3_03360 1.19e-203 565.0 COG4535@1|root,COG4535@2|Bacteria,1QTU8@1224|Proteobacteria,1RMKX@1236|Gammaproteobacteria,1XT0H@135623|Vibrionales 135623|Vibrionales P Mg2 and Co2 transporter CorC corC GO:0001897,GO:0001906,GO:0001907,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009405,GO:0009987,GO:0016020,GO:0019835,GO:0019836,GO:0031640,GO:0035821,GO:0044003,GO:0044004,GO:0044179,GO:0044364,GO:0044403,GO:0044419,GO:0044464,GO:0044764,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0071944 - ko:K06189 - - - - ko00000,ko02000 9.A.40.1.2 - - CBS,CorC_HlyC k141_11694_5 1280001.BAOA01000003_gene3707 1.99e-103 299.0 COG0319@1|root,COG0319@2|Bacteria,1MZ67@1224|Proteobacteria,1S6BS@1236|Gammaproteobacteria,1XWWW@135623|Vibrionales 135623|Vibrionales J Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ybeY - - ko:K07042 - - - - ko00000,ko03009 - - - UPF0054 k141_11694_6 223926.28805718 7.41e-254 697.0 COG1702@1|root,COG1702@2|Bacteria,1MVDV@1224|Proteobacteria,1RP2Y@1236|Gammaproteobacteria,1XVDI@135623|Vibrionales 135623|Vibrionales T Phosphate starvation-inducible protein PhoH ybeZ - - ko:K06217 - - - - ko00000 - - - PhoH k141_11694_7 223926.28805719 0.0 926.0 COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,1RMD8@1236|Gammaproteobacteria,1XSQ1@135623|Vibrionales 135623|Vibrionales J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine miaB - 2.8.4.3 ko:K06168 - - R10645,R10646,R10647 RC00003,RC00980,RC03221,RC03222 ko00000,ko01000,ko03016 - - - Radical_SAM,TRAM,UPF0004 k141_11694_8 1116375.VEJY3_03380 1.25e-140 406.0 COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,1RND5@1236|Gammaproteobacteria,1XU6J@135623|Vibrionales 135623|Vibrionales CH COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases ubiF - - ko:K03184 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R06146,R08775 RC01254 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,FAD_binding_3,SE k141_37559_1 218284.CCDN010000002_gene2078 1.56e-164 472.0 COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4HC58@91061|Bacilli,1ZB1Y@1386|Bacillus 91061|Bacilli S COG0488 ATPase components of ABC transporters with duplicated ATPase domains yheS_1 - - - - - - - - - - - ABC_tran,ABC_tran_Xtn k141_32855_1 218284.CCDN010000008_gene4151 1.71e-54 179.0 COG0803@1|root,COG0803@2|Bacteria,1TPG7@1239|Firmicutes,4H9UN@91061|Bacilli,1ZC2Z@1386|Bacillus 91061|Bacilli P Belongs to the bacterial solute-binding protein 9 family adcA - - ko:K09815,ko:K09818 ko02010,map02010 M00242,M00243 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 - - ZnuA k141_17392_1 1042377.AFPJ01000036_gene1173 5.14e-72 236.0 COG0665@1|root,COG4121@1|root,COG0665@2|Bacteria,COG4121@2|Bacteria,1MZW5@1224|Proteobacteria,1RMTE@1236|Gammaproteobacteria,464VK@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 mnmC GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0004808,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016491,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363 2.1.1.61 ko:K15461 - - R00601,R08702 RC00003,RC00053,RC00060,RC01483 ko00000,ko01000,ko03016 - - - DAO,Methyltransf_30 k141_35426_1 1453501.JELR01000001_gene2069 2.19e-136 393.0 COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,1RN22@1236|Gammaproteobacteria,465BM@72275|Alteromonadaceae 1236|Gammaproteobacteria J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily pheS GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 ko:K01889 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iJN746.PP_2469 Phe_tRNA-synt_N,tRNA-synt_2d k141_7955_210 1564096.A0A0A0YVJ4_9CAUD 2.13e-28 115.0 4QHG7@10239|Viruses,4QRS2@28883|Caudovirales,4QJX5@10662|Myoviridae 10662|Myoviridae S PD-(D/E)XK nuclease superfamily - - - - - - - - - - - - - k141_7955_213 445683.E3SJQ4_9CAUD 2.06e-61 206.0 4QAJD@10239|Viruses,4QW4M@35237|dsDNA viruses no RNA stage,4QQ7U@28883|Caudovirales,4QIAP@10662|Myoviridae 10662|Myoviridae S gp32 DNA binding protein like - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039686,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k141_7955_223 1564096.A0A0A0YS49_9CAUD 8.33e-50 169.0 4QDKB@10239|Viruses,4QPPF@28883|Caudovirales,4QINJ@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k141_7955_225 1262513.K7YY80_9CAUD 4.53e-27 103.0 4QC6X@10239|Viruses,4QWE5@35237|dsDNA viruses no RNA stage,4QRTD@28883|Caudovirales,4QIP8@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k141_7955_228 1589733.A0A0C5ADW7_9CAUD 0.000337 45.4 4QFF8@10239|Viruses,4QQMR@28883|Caudovirales,4QJ45@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k141_7955_230 1589733.A0A0C5ADT0_9CAUD 4.96e-38 133.0 4QDXQ@10239|Viruses,4QQF2@28883|Caudovirales,4QIMB@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k141_7955_243 1493512.A0A0E3FAX6_9CAUD 7.39e-12 69.7 4QBKS@10239|Viruses,4QPK5@28883|Caudovirales,4QIYJ@10662|Myoviridae 10662|Myoviridae S Base plate wedge protein 53 - - - - - - - - - - - - - k141_7955_244 1283076.M1IDA1_9CAUD 1.71e-23 106.0 4QAKW@10239|Viruses,4QX74@35237|dsDNA viruses no RNA stage,4QPSV@28883|Caudovirales,4QI33@10662|Myoviridae 10662|Myoviridae - - - GO:0005575,GO:0019012,GO:0044423,GO:0098015,GO:0098025 - - - - - - - - - - - k141_7955_246 1204516.I6X7Y8_9CAUD 1.09e-15 87.8 4QCR0@10239|Viruses,4QVAV@35237|dsDNA viruses no RNA stage,4QPFK@28883|Caudovirales,4QI4N@10662|Myoviridae 10662|Myoviridae S cell wall macromolecule catabolic process - GO:0003674,GO:0003796,GO:0003824,GO:0004553,GO:0005488,GO:0005515,GO:0005575,GO:0008150,GO:0009405,GO:0009987,GO:0016043,GO:0016787,GO:0016798,GO:0019012,GO:0022607,GO:0033922,GO:0042802,GO:0043933,GO:0044085,GO:0044403,GO:0044409,GO:0044411,GO:0044419,GO:0044423,GO:0051259,GO:0051260,GO:0051701,GO:0051704,GO:0051828,GO:0051830,GO:0061783,GO:0065003,GO:0070206,GO:0070207,GO:0071840,GO:0085027,GO:0098015,GO:0098025 - - - - - - - - - - - k141_7955_247 1391188.A0A068EMP3_9CAUD 2.77e-20 108.0 4QBW1@10239|Viruses,4QYKH@35237|dsDNA viruses no RNA stage,4QSKV@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k141_33042_1 583355.Caka_2452 1.02e-52 181.0 COG2256@1|root,COG2256@2|Bacteria,46S7H@74201|Verrucomicrobia,3K7HY@414999|Opitutae 414999|Opitutae L MgsA AAA+ ATPase C terminal - - - ko:K07478 - - - - ko00000 - - - AAA,AAA_assoc_2,MgsA_C k141_36451_1 218284.CCDN010000002_gene2172 4.05e-88 268.0 COG4585@1|root,COG4585@2|Bacteria,1TPDG@1239|Firmicutes,4HC7E@91061|Bacilli,1ZB48@1386|Bacillus 91061|Bacilli T Histidine kinase vraS - 2.7.13.3 ko:K07681,ko:K11617 ko02020,map02020 M00480,M00481,M00754 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA_3 k141_36451_2 218284.CCDN010000002_gene2173 8.16e-70 215.0 COG2197@1|root,COG2197@2|Bacteria,1TQ1U@1239|Firmicutes,4HA4B@91061|Bacilli,1ZAT4@1386|Bacillus 91061|Bacilli KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain vraR - - ko:K07694,ko:K11618 ko02020,map02020 M00480,M00481,M00754 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg k141_35628_1 1117108.PAALTS15_15481 3.58e-21 93.2 COG2227@1|root,COG2227@2|Bacteria,1VZEI@1239|Firmicutes,4HDZM@91061|Bacilli,26UP6@186822|Paenibacillaceae 91061|Bacilli H Methyltransferase domain - - - - - - - - - - - - Methyltransf_11,Methyltransf_25 k141_24853_1 1294265.JCM21738_2830 1.12e-71 223.0 2DB9X@1|root,2Z7ZS@2|Bacteria,1VS9F@1239|Firmicutes,4HTUJ@91061|Bacilli,1ZC1U@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3445) - - 1.14.13.238 ko:K22342 - - - - ko00000,ko01000 - - - DUF3445 k141_37718_1 1515746.HR45_07250 4.62e-275 767.0 COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,1S0X9@1236|Gammaproteobacteria,2QBEN@267890|Shewanellaceae 1236|Gammaproteobacteria L Helix-hairpin-helix containing domain VPA1266 - 3.1.11.5 ko:K03581 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_30,HHH_4,UvrD_C_2,Viral_helicase1 k141_37718_2 223926.28809635 2.37e-93 273.0 2BGBK@1|root,32A98@2|Bacteria,1PYKN@1224|Proteobacteria,1TJTC@1236|Gammaproteobacteria,1Y1NG@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_37718_3 94122.Shewana3_2917 1.28e-152 429.0 COG2267@1|root,COG2267@2|Bacteria,1R7QW@1224|Proteobacteria,1S2X8@1236|Gammaproteobacteria 1236|Gammaproteobacteria I carboxylic ester hydrolase activity - - - - - - - - - - - - - k141_37718_4 94122.Shewana3_2916 0.0 1585.0 COG0582@1|root,COG0582@2|Bacteria,1MV71@1224|Proteobacteria,1RQMW@1236|Gammaproteobacteria,2QB58@267890|Shewanellaceae 1236|Gammaproteobacteria L Putative phage integrase - - - - - - - - - - - - PHINT_rpt,Phage_Integr_2,Phage_integrase k141_36458_13 1219065.VPR01S_07_01850 7.86e-44 142.0 2EA3G@1|root,3348H@2|Bacteria,1N89N@1224|Proteobacteria,1SF7H@1236|Gammaproteobacteria,1XYB3@135623|Vibrionales 135623|Vibrionales S Domain of unknown function (DUF4177) - - - - - - - - - - - - DUF4177 k141_36458_14 945543.VIBR0546_12177 9.19e-65 199.0 2DBBF@1|root,32TX4@2|Bacteria,1N03C@1224|Proteobacteria,1SE8G@1236|Gammaproteobacteria,1XXU4@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_36458_15 1219076.N646_0512 1.06e-122 351.0 COG1182@1|root,COG1182@2|Bacteria,1P59R@1224|Proteobacteria,1S337@1236|Gammaproteobacteria,1XW8V@135623|Vibrionales 135623|Vibrionales C Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity azoR - - ko:K01118 - - - - ko00000,ko01000 - - - Flavodoxin_2 k141_36458_16 223926.28806444 3.77e-262 756.0 COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,1RMU1@1236|Gammaproteobacteria,1XSCH@135623|Vibrionales 135623|Vibrionales L COG1643 HrpA-like helicases hrpA - 3.6.4.13 ko:K03578 - - - - ko00000,ko01000 - - - DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind k141_17630_1 1279017.AQYJ01000027_gene1719 4.75e-197 583.0 COG0803@1|root,COG0803@2|Bacteria,1MY4H@1224|Proteobacteria,1S26I@1236|Gammaproteobacteria,46AMU@72275|Alteromonadaceae 1236|Gammaproteobacteria P Belongs to the bacterial solute-binding protein 9 family - - - - - - - - - - - - DUF4175 k141_4561_1 218284.CCDN010000002_gene2156 5.53e-270 768.0 COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,4HAFP@91061|Bacilli,1ZBJ3@1386|Bacillus 91061|Bacilli V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family swrC - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran k141_4561_2 218284.CCDN010000002_gene2155 3.82e-193 537.0 COG1309@1|root,COG1309@2|Bacteria,1UDHR@1239|Firmicutes,4HFAX@91061|Bacilli,1ZFND@1386|Bacillus 91061|Bacilli K Transcriptional regulator yerO GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 - - - - - - - - - - TetR_N k141_7987_1 997296.PB1_15459 1.31e-86 273.0 COG0768@1|root,COG0768@2|Bacteria,1TQKI@1239|Firmicutes,4HC5S@91061|Bacilli,1ZBDB@1386|Bacillus 91061|Bacilli M Penicillin-binding Protein pbpI - - ko:K21468 - - - - ko00000,ko01011 - - - PBP_dimer,Transpeptidase k141_15191_1 35841.BT1A1_2285 6.36e-76 236.0 COG0688@1|root,COG0688@2|Bacteria,1TR34@1239|Firmicutes,4HB6I@91061|Bacilli,1ZAZ4@1386|Bacillus 91061|Bacilli I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) psd - 4.1.1.65 ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 M00093 R02055 RC00299 ko00000,ko00001,ko00002,ko01000 - - - PS_Dcarbxylase k141_20197_1 1347086.CCBA010000026_gene3269 4.81e-113 333.0 COG1015@1|root,COG1015@2|Bacteria,1TP70@1239|Firmicutes,4H9RU@91061|Bacilli,1ZBG0@1386|Bacillus 91061|Bacilli G Phosphotransfer between the C1 and C5 carbon atoms of pentose deoB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008973,GO:0009987,GO:0016853,GO:0016866,GO:0016868,GO:0034641,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360 5.4.2.7 ko:K01839 ko00030,ko00230,map00030,map00230 - R01057,R02749 RC00408 ko00000,ko00001,ko01000 - - - Metalloenzyme k141_33080_1 485913.Krac_8845 1.53e-06 50.4 COG0542@1|root,COG0542@2|Bacteria,2G5QU@200795|Chloroflexi 200795|Chloroflexi O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE clpB - - ko:K03695 ko04213,map04213 - - - ko00000,ko00001,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N k141_21149_1 1294265.JCM21738_289 2.23e-27 107.0 COG1220@1|root,COG1220@2|Bacteria,1TPKQ@1239|Firmicutes,4HA83@91061|Bacilli,1ZCWK@1386|Bacillus 91061|Bacilli O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis hslU - - ko:K03667 - - - - ko00000,ko03110 - - - AAA_2,ClpB_D2-small k141_21149_2 1034347.CAHJ01000010_gene2084 3.4e-70 215.0 COG5405@1|root,COG5405@2|Bacteria,1TPXK@1239|Firmicutes,4H9PD@91061|Bacilli,1ZCMN@1386|Bacillus 91061|Bacilli O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery hslV - 3.4.25.2 ko:K01419 - - - - ko00000,ko01000,ko01002 - - - Proteasome k141_17632_1 1294265.JCM21738_1233 3.58e-26 105.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,1ZB7V@1386|Bacillus 91061|Bacilli I Belongs to the thiolase family pcaF - 2.3.1.174,2.3.1.223 ko:K02615 ko00360,ko01120,map00360,map01120 - R00829,R09839 RC00004,RC00326,RC03003 ko00000,ko00001,ko01000 - - - Thiolase_C,Thiolase_N k141_29623_1 1042377.AFPJ01000019_gene2494 3.67e-114 333.0 COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,1RNJR@1236|Gammaproteobacteria,464PB@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) pyrF GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 ko:K01591 ko00240,ko01100,map00240,map01100 M00051 R00965 RC00409 ko00000,ko00001,ko00002,ko01000 - - iECO103_1326.ECO103_1444,iECSF_1327.ECSF_1264,iSFV_1184.SFV_1294,iSF_1195.SF1285,iSFxv_1172.SFxv_1457,iS_1188.S1368,ic_1306.c1750 OMPdecase k141_29623_2 1453501.JELR01000001_gene2058 2.89e-244 676.0 COG2956@1|root,COG2956@2|Bacteria,1MVDP@1224|Proteobacteria,1RP29@1236|Gammaproteobacteria,4664S@72275|Alteromonadaceae 1236|Gammaproteobacteria G Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane lapB GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008653,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046872,GO:0071704,GO:0071944,GO:1901135,GO:1903509 - ko:K19804 - - - - ko00000 - - - TPR_16,TPR_19,TPR_7,TPR_8 k141_29623_4 1279017.AQYJ01000026_gene190 1.02e-60 187.0 COG0776@1|root,COG0776@2|Bacteria,1MZ7M@1224|Proteobacteria,1S8XZ@1236|Gammaproteobacteria,467QW@72275|Alteromonadaceae 1236|Gammaproteobacteria K This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control himD GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2001141 - ko:K05788 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding k141_29623_5 1453501.JELR01000001_gene2055 1.12e-198 562.0 COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,1RMFY@1236|Gammaproteobacteria,464BF@72275|Alteromonadaceae 1236|Gammaproteobacteria J thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence rpsA GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113,GO:2000765,GO:2000766 - ko:K02945 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - S1 k141_3356_1 1042377.AFPJ01000024_gene808 4.58e-49 161.0 COG0560@1|root,COG0560@2|Bacteria,1RA1A@1224|Proteobacteria,1S21J@1236|Gammaproteobacteria,466GA@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0560 Phosphoserine phosphatase - - - - - - - - - - - - HAD k141_10578_1 223926.28806444 1.44e-144 442.0 COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,1RMU1@1236|Gammaproteobacteria,1XSCH@135623|Vibrionales 135623|Vibrionales L COG1643 HrpA-like helicases hrpA - 3.6.4.13 ko:K03578 - - - - ko00000,ko01000 - - - DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind k141_13075_1 218284.CCDN010000007_gene3804 8.91e-68 214.0 COG0668@1|root,COG0668@2|Bacteria,1TR9Z@1239|Firmicutes,4HCB8@91061|Bacilli,1ZCW4@1386|Bacillus 91061|Bacilli M Mechanosensitive ion channel ykuT - - ko:K22044 - - - - ko00000,ko02000 1.A.23.3 - - MS_channel k141_13075_2 218284.CCDN010000007_gene3803 1.61e-135 385.0 2ADZG@1|root,313RY@2|Bacteria,1V6JT@1239|Firmicutes,4HH5B@91061|Bacilli,1ZCER@1386|Bacillus 91061|Bacilli S Sporulation protein YyaC yyaC - - - - - - - - - - - DUF1256 k141_24926_1 218284.CCDN010000010_gene4347 5.15e-93 272.0 COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,4HFPW@91061|Bacilli,1ZFMY@1386|Bacillus 91061|Bacilli J binds to the 23S rRNA rplO GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02876 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27A k141_4563_1 46429.BV95_01521 2.82e-46 160.0 COG0788@1|root,COG0788@2|Bacteria,1MVCF@1224|Proteobacteria,2TR4V@28211|Alphaproteobacteria,2K0F7@204457|Sphingomonadales 204457|Sphingomonadales F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) purU - 3.5.1.10 ko:K01433 ko00630,ko00670,map00630,map00670 - R00944 RC00026,RC00111 ko00000,ko00001,ko01000 - - - Formyl_trans_N k141_29624_1 1453501.JELR01000002_gene104 3.13e-25 108.0 COG3325@1|root,COG3979@1|root,COG3325@2|Bacteria,COG3979@2|Bacteria,1MWAR@1224|Proteobacteria,1RPNS@1236|Gammaproteobacteria,4672D@72275|Alteromonadaceae 1236|Gammaproteobacteria G Glyco_18 chiA - 3.2.1.14 ko:K01183 ko00520,ko01100,map00520,map01100 - R01206,R02334 RC00467 ko00000,ko00001,ko01000 - GH18 - CBM_5_12,ChitinaseA_N,Glyco_hydro_18,REJ k141_36459_1 42565.FP66_03440 8.51e-119 343.0 COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,1RPMP@1236|Gammaproteobacteria,1XJDI@135619|Oceanospirillales 135619|Oceanospirillales M Domain amino terminal to FKBP-type peptidyl-prolyl isomerase - - 5.2.1.8 ko:K03773 - - - - ko00000,ko01000,ko03110 - - - FKBP_C,FKBP_N k141_36459_2 42565.FP66_03445 4.79e-45 148.0 COG0589@1|root,COG0589@2|Bacteria,1RINB@1224|Proteobacteria,1S68P@1236|Gammaproteobacteria,1XJY2@135619|Oceanospirillales 135619|Oceanospirillales T Universal stress protein - - - - - - - - - - - - Usp k141_21150_1 1196031.ALEG01000020_gene3040 2.29e-134 384.0 COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,4HAB1@91061|Bacilli,1ZBQ5@1386|Bacillus 91061|Bacilli P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system pstB - 3.6.3.27 ko:K02036 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 - iSB619.SA_RS06920 ABC_tran k141_15192_1 218284.CCDN010000008_gene4172 1.31e-75 231.0 COG2267@1|root,COG2267@2|Bacteria,1UZ5S@1239|Firmicutes,4HEHP@91061|Bacilli,1ZBD1@1386|Bacillus 91061|Bacilli I Alpha beta hydrolase ytpA GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0008150,GO:0008152,GO:0016020,GO:0016298,GO:0016787,GO:0016788,GO:0044238,GO:0071704 3.1.1.5 ko:K01048 ko00564,map00564 - - - ko00000,ko00001,ko01000 - - - Hydrolase_4 k141_24927_2 935836.JAEL01000049_gene5372 5.78e-96 286.0 COG0745@1|root,COG0745@2|Bacteria,1TTBI@1239|Firmicutes,4HBQ0@91061|Bacilli,1ZEIK@1386|Bacillus 91061|Bacilli T Transcriptional regulatory protein, C terminal - - - - - - - - - - - - Response_reg,Trans_reg_C k141_20199_1 1453501.JELR01000002_gene340 5.48e-24 100.0 COG3182@1|root,COG3182@2|Bacteria,1MW2S@1224|Proteobacteria,1RQYY@1236|Gammaproteobacteria,46CKU@72275|Alteromonadaceae 1236|Gammaproteobacteria S PepSY-associated TM region - - - - - - - - - - - - PepSY,PepSY_TM k141_20199_2 344747.PM8797T_05705 7.65e-46 157.0 COG0604@1|root,COG0604@2|Bacteria,2J2QJ@203682|Planctomycetes 203682|Planctomycetes C Zinc-binding dehydrogenase - - - - - - - - - - - - ADH_N,ADH_zinc_N_2 k141_31626_1 665952.HMPREF1015_01741 9.5e-159 457.0 COG0161@1|root,COG0161@2|Bacteria,1TP9N@1239|Firmicutes,4H9QK@91061|Bacilli,1ZR67@1386|Bacillus 91061|Bacilli H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor bioA - 2.6.1.105,2.6.1.62 ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R03231,R10699 RC00006,RC00062,RC00887 ko00000,ko00001,ko00002,ko01000,ko01007 - - iSB619.SA_RS12705 Aminotran_3 k141_29625_1 665959.HMPREF1013_05437 3.37e-121 375.0 COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,4HAFP@91061|Bacilli,1ZBJ3@1386|Bacillus 91061|Bacilli V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family swrC - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran k141_3357_1 1453501.JELR01000005_gene1665 9.26e-75 253.0 COG2982@1|root,COG2982@2|Bacteria,1MUME@1224|Proteobacteria,1RNPC@1236|Gammaproteobacteria,464KK@72275|Alteromonadaceae 1236|Gammaproteobacteria M Domain of Unknown Function (DUF748) - - - - - - - - - - - - DUF748,OmpA k141_24928_2 935836.JAEL01000005_gene2708 4.19e-53 169.0 COG1403@1|root,COG1403@2|Bacteria,1VKF1@1239|Firmicutes,4IRTY@91061|Bacilli,1ZRY0@1386|Bacillus 91061|Bacilli V HNH endonuclease - - - - - - - - - - - - HNH k141_17633_1 218284.CCDN010000007_gene3986 4.73e-116 347.0 COG0840@1|root,COG0840@2|Bacteria,1TPI1@1239|Firmicutes,4HADY@91061|Bacilli,1ZD20@1386|Bacillus 91061|Bacilli NT Chemotaxis mcpA - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal k141_17633_2 218284.CCDN010000007_gene3987 2.68e-103 299.0 COG0698@1|root,COG0698@2|Bacteria,1V3HE@1239|Firmicutes,4HGXD@91061|Bacilli,1ZFM4@1386|Bacillus 91061|Bacilli G Ribose 5-phosphate isomerase rpiB - 5.3.1.6 ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01056,R09030 RC00376,RC00434 ko00000,ko00001,ko00002,ko01000 - - - LacAB_rpiB k141_34338_1 641526.ADIWIN_0754 4.09e-77 245.0 COG4805@1|root,COG4805@2|Bacteria,4NFAK@976|Bacteroidetes,1HXAT@117743|Flavobacteriia 976|Bacteroidetes S protein conserved in bacteria - - - - - - - - - - - - DUF885 k141_21151_1 218284.CCDN010000001_gene1120 2.79e-163 462.0 2E49C@1|root,32Z54@2|Bacteria,1VH6M@1239|Firmicutes,4HQD6@91061|Bacilli,1ZDJG@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_4566_1 1307436.PBF_10642 3.93e-72 231.0 COG1233@1|root,COG1233@2|Bacteria,1TS4A@1239|Firmicutes,4HB9J@91061|Bacilli,1ZCTK@1386|Bacillus 91061|Bacilli Q COG1233 Phytoene dehydrogenase and related proteins - - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 ko:K10027 ko00906,ko01100,ko01110,map00906,map01100,map01110 - R04787,R04798,R04800,R09691,R09692 RC01214,RC02088,RC02605 ko00000,ko00001,ko01000 - - - Amino_oxidase k141_26212_1 218284.CCDN010000005_gene3227 8.17e-98 295.0 COG0477@1|root,COG2814@2|Bacteria,1UXYG@1239|Firmicutes,4HBZB@91061|Bacilli,1ZQ79@1386|Bacillus 91061|Bacilli EGP COG0477 Permeases of the major facilitator superfamily ynfM3 - - - - - - - - - - - MFS_1,Sugar_tr k141_14324_1 1116375.VEJY3_04280 6.65e-97 289.0 COG1441@1|root,COG1441@2|Bacteria,1MV33@1224|Proteobacteria,1RRC0@1236|Gammaproteobacteria,1XTPS@135623|Vibrionales 135623|Vibrionales H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) menC GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.2.1.113 ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R04031 RC01053 ko00000,ko00001,ko00002,ko01000 - - - MR_MLE_C k141_3633_1 171693.BN988_02620 1.01e-60 197.0 COG1834@1|root,COG1834@2|Bacteria,1VDT8@1239|Firmicutes,4ISAW@91061|Bacilli,23JG2@182709|Oceanobacillus 91061|Bacilli E Amidinotransferase - - - - - - - - - - - - Amidinotransf k141_29749_1 218284.CCDN010000009_gene4320 4.38e-32 120.0 COG0477@1|root,COG2814@2|Bacteria,1TS3C@1239|Firmicutes,4HC3B@91061|Bacilli,1ZS79@1386|Bacillus 91061|Bacilli EGP Nucleoside H+ symporter ywbF - - ko:K05820 - - - - ko00000,ko02000 2.A.1.27 - - MFS_1_like k141_36893_2 218284.CCDN010000001_gene971 1.15e-52 181.0 COG1154@1|root,COG1154@2|Bacteria,1TP37@1239|Firmicutes,4H9QW@91061|Bacilli,1ZBHF@1386|Bacillus 91061|Bacilli H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) dxs - 2.2.1.7 ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 M00096 R05636 RC00032 ko00000,ko00001,ko00002,ko01000 - - - DXP_synthase_N,Transket_pyr,Transketolase_C k141_3634_1 390989.JOEG01000010_gene498 1.93e-15 80.9 COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4DBR0@85008|Micromonosporales 201174|Actinobacteria IQ AMP-binding enzyme C-terminal domain - - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding,AMP-binding_C k141_14325_1 1294265.JCM21738_612 2.6e-112 333.0 COG0536@1|root,COG0536@2|Bacteria,1TPX7@1239|Firmicutes,4H9P8@91061|Bacilli,1ZCM4@1386|Bacillus 91061|Bacilli S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control obg GO:0000003,GO:0000160,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0017076,GO:0019001,GO:0019954,GO:0023052,GO:0030436,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035556,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043934,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03979 - - - - ko00000,ko01000,ko03009 - - - DUF1967,GTP1_OBG,MMR_HSR1 k141_36894_1 1121929.KB898667_gene3633 5.29e-24 99.4 COG0246@1|root,COG0246@2|Bacteria,1TPZU@1239|Firmicutes,4H9S3@91061|Bacilli,47049@74385|Gracilibacillus 91061|Bacilli G Mannitol dehydrogenase C-terminal domain mtlD GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006059,GO:0006066,GO:0008150,GO:0008152,GO:0008926,GO:0009056,GO:0009987,GO:0016052,GO:0016491,GO:0016614,GO:0016616,GO:0019400,GO:0019405,GO:0019407,GO:0019592,GO:0019594,GO:0019751,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046164,GO:0046174,GO:0055114,GO:0071704,GO:1901575,GO:1901615,GO:1901616 1.1.1.17 ko:K00009 ko00051,map00051 - R02703 RC00085 ko00000,ko00001,ko01000 - - - Mannitol_dh,Mannitol_dh_C k141_36894_2 218284.CCDN010000002_gene2731 3.85e-74 241.0 COG3711@1|root,COG3711@2|Bacteria,1TQT1@1239|Firmicutes,4HABH@91061|Bacilli,1ZBYI@1386|Bacillus 91061|Bacilli K transcriptional regulator, MtlR mtlR - - ko:K03483 - - - - ko00000,ko03000 - - - HTH_11,Mga,PRD,PTS_EIIA_2,PTS_IIB k141_8395_1 218284.CCDN010000007_gene3910 6.76e-178 504.0 COG2031@1|root,COG2031@2|Bacteria,1TPCQ@1239|Firmicutes,4HAQF@91061|Bacilli,1ZECR@1386|Bacillus 91061|Bacilli I Short chain fatty acid transporter atoE - - ko:K02106 ko02020,map02020 - - - ko00000,ko00001 2.A.73.1 - - SCFA_trans k141_29750_1 1473546.CH76_09800 2.27e-62 207.0 COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HAHB@91061|Bacilli,3IXJC@400634|Lysinibacillus 91061|Bacilli IQ AMP-binding protein yngI - - ko:K00666 - - - - ko00000,ko01000,ko01004 - - - AMP-binding,AMP-binding_C k141_29750_2 35128.Thaps260885 1.11e-12 68.9 COG0077@1|root,KOG2797@2759|Eukaryota,2XEMP@2836|Bacillariophyta 2836|Bacillariophyta E Prephenate dehydratase - - - - - - - - - - - - PDT k141_20250_1 218284.CCDN010000001_gene1955 2.36e-66 206.0 COG1366@1|root,COG1366@2|Bacteria,1VFWM@1239|Firmicutes,4HPSG@91061|Bacilli,1ZHKE@1386|Bacillus 91061|Bacilli T Belongs to the anti-sigma-factor antagonist family - - - ko:K17763 - - - - ko00000,ko03021 - - - STAS k141_20250_2 218284.CCDN010000001_gene1951 1.25e-27 102.0 2E6HR@1|root,33150@2|Bacteria,1VF6G@1239|Firmicutes,4IR8Y@91061|Bacilli,1ZKDM@1386|Bacillus 91061|Bacilli S YCII-related domain - - - - - - - - - - - - YCII k141_22643_1 1122614.JHZF01000011_gene1571 0.000225 42.4 2E4B3@1|root,32Z6S@2|Bacteria,1N8PJ@1224|Proteobacteria,2UHKR@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_13151_2 265729.GS18_0220250 4.12e-286 785.0 COG1653@1|root,COG1653@2|Bacteria,1TQHT@1239|Firmicutes,4HAH2@91061|Bacilli,1ZD76@1386|Bacillus 91061|Bacilli G Bacterial extracellular solute-binding protein - - - ko:K10117 ko02010,map02010 M00196 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.28 - - SBP_bac_8 k141_24998_2 218284.CCDN010000007_gene3799 9.65e-173 486.0 COG1475@1|root,COG1475@2|Bacteria,1TP0I@1239|Firmicutes,4HAC6@91061|Bacilli,1ZCDV@1386|Bacillus 91061|Bacilli D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage noc - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc k141_2433_1 935836.JAEL01000011_gene5155 1.72e-135 414.0 COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,4HAEY@91061|Bacilli,1ZCEM@1386|Bacillus 91061|Bacilli F Belongs to the CarB family carB GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS k141_21455_1 1148.1652237 3.34e-29 108.0 COG1917@1|root,COG1917@2|Bacteria,1G8D7@1117|Cyanobacteria,1H6P7@1142|Synechocystis 1117|Cyanobacteria S Cupin domain - - - ko:K11312 - - - - ko00000 - - - AraC_binding,Cupin_2,Nif11 k141_21455_2 1279017.AQYJ01000029_gene3675 2.6e-51 181.0 COG4773@1|root,COG4773@2|Bacteria,1QTXJ@1224|Proteobacteria,1T2NX@1236|Gammaproteobacteria,46D3S@72275|Alteromonadaceae 1236|Gammaproteobacteria P TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_15522_1 520999.PROVALCAL_03373 5.41e-29 119.0 COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,1RNI4@1236|Gammaproteobacteria,3Z7VR@586|Providencia 1236|Gammaproteobacteria C NADH dehydrogenase I chain M (NADH-ubiquinone oxidoreductase chain M) (NUO13) K00342 nuoM GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0030964,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0048037,GO:0048038,GO:0048039,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1902600,GO:1990204 1.6.5.3 ko:K00342 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - iSDY_1059.SDY_2473 Proton_antipo_M k141_15522_2 1279017.AQYJ01000023_gene3162 1.6e-267 752.0 COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,1RNKN@1236|Gammaproteobacteria,469GC@72275|Alteromonadaceae 1236|Gammaproteobacteria CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit nuoL GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015672,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0030964,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0051179,GO:0051234,GO:0055085,GO:0070469,GO:0070470,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1902600,GO:1990204 1.6.5.3 ko:K00341 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - e_coli_core.b2278,iAF1260.b2278,iBWG_1329.BWG_2052,iECDH10B_1368.ECDH10B_2440,iECDH1ME8569_1439.ECDH1ME8569_2215,iEcDH1_1363.EcDH1_1379,iJN746.PP_4129,iJO1366.b2278,iJR904.b2278,iY75_1357.Y75_RS11945 Proton_antipo_M,Proton_antipo_N k141_15522_3 1279017.AQYJ01000023_gene3163 8.31e-33 117.0 COG0713@1|root,COG0713@2|Bacteria,1RH0S@1224|Proteobacteria,1S6FN@1236|Gammaproteobacteria,468MA@72275|Alteromonadaceae 1236|Gammaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoK GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 ko:K00340 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q2 k141_15522_4 290398.Csal_3124 2.25e-50 167.0 COG0839@1|root,COG0839@2|Bacteria,1MWJV@1224|Proteobacteria,1S65T@1236|Gammaproteobacteria,1XQBW@135619|Oceanospirillales 135619|Oceanospirillales C NADH-ubiquinone/plastoquinone oxidoreductase chain 6 - - 1.6.5.3 ko:K00339 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q3 k141_30973_1 1453501.JELR01000002_gene474 6.08e-74 228.0 COG1737@1|root,COG1737@2|Bacteria,1MV3U@1224|Proteobacteria,1RNC4@1236|Gammaproteobacteria,46697@72275|Alteromonadaceae 1236|Gammaproteobacteria K Helix-turn-helix domain, rpiR family - - - ko:K19337 - - - - ko00000,ko03000 - - - HTH_6,SIS k141_8396_2 1279017.AQYJ01000003_gene1533 4.56e-43 140.0 arCOG05874@1|root,2ZJ01@2|Bacteria,1N8VY@1224|Proteobacteria,1SHGZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_2465_1 1116375.VEJY3_06480 1.37e-54 174.0 29A8I@1|root,2ZX9F@2|Bacteria,1PB16@1224|Proteobacteria,1THUG@1236|Gammaproteobacteria,1XXKI@135623|Vibrionales 135623|Vibrionales - - VP1339 - - - - - - - - - - - - k141_35733_2 1121324.CLIT_23c02630 4.5e-10 62.8 COG3437@1|root,COG3437@2|Bacteria,1TQ0S@1239|Firmicutes 1239|Firmicutes T Diguanylate cyclase - - - - - - - - - - - - GAF_2,GGDEF,HD,HD_5,HisKA_7TM,PAS_3,PAS_4,PAS_9 k141_26229_1 218284.CCDN010000001_gene967 1.21e-10 60.8 COG1570@1|root,COG1570@2|Bacteria,1TP4E@1239|Firmicutes,4HAN2@91061|Bacilli,1ZB5Q@1386|Bacillus 91061|Bacilli L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseA - 3.1.11.6 ko:K03601 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_L,tRNA_anti_2 k141_26229_2 218284.CCDN010000001_gene968 8.14e-42 137.0 COG1722@1|root,COG1722@2|Bacteria,1VK9I@1239|Firmicutes,4HNRB@91061|Bacilli,1ZIVS@1386|Bacillus 91061|Bacilli L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseB - 3.1.11.6 ko:K03602 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_S k141_26229_3 985665.HPL003_24055 3.75e-13 70.1 COG0142@1|root,COG0142@2|Bacteria,1TPQY@1239|Firmicutes,4HA8E@91061|Bacilli,26S75@186822|Paenibacillaceae 91061|Bacilli H Belongs to the FPP GGPP synthase family ispA GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0071704,GO:1901576 2.5.1.1,2.5.1.10,2.5.1.29 ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00366 R01658,R02003,R02061 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 - - - polyprenyl_synt k141_22675_1 2754.EH55_11025 4.03e-33 130.0 COG0111@1|root,COG0111@2|Bacteria,3TA9D@508458|Synergistetes 508458|Synergistetes EH D-isomer specific 2-hydroxyacid dehydrogenase - - 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C,ACT k141_29773_1 1196323.ALKF01000177_gene1076 4.04e-83 264.0 COG1001@1|root,COG1001@2|Bacteria,1TP84@1239|Firmicutes,4HBB2@91061|Bacilli,26T7U@186822|Paenibacillaceae 91061|Bacilli F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family ade GO:0003674,GO:0003824,GO:0006040,GO:0006044,GO:0006046,GO:0008150,GO:0008152,GO:0008448,GO:0009056,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0046348,GO:0071704,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901575 3.5.4.2 ko:K01486 ko00230,ko01100,map00230,map01100 - R01244 RC00477 ko00000,ko00001,ko01000 - - iYO844.BSU14520 Adenine_deam_C,Amidohydro_1 k141_27378_2 348824.LPU83_0887 6.85e-22 94.7 2AI77@1|root,318MJ@2|Bacteria,1MXJB@1224|Proteobacteria,2TW9U@28211|Alphaproteobacteria,4BB0C@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_32148_1 1385513.N780_15330 1.61e-12 67.0 COG4146@1|root,COG4146@2|Bacteria,1UHPR@1239|Firmicutes,4HDFI@91061|Bacilli,2YBF6@289201|Pontibacillus 91061|Bacilli S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - ko:K03307 - - - - ko00000 2.A.21 - - SSF k141_32148_2 1074451.CRL705_1555 4.88e-17 80.1 COG0153@1|root,COG0153@2|Bacteria,1TPD0@1239|Firmicutes,4HARP@91061|Bacilli,3F3Q9@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) galK GO:0005975,GO:0005996,GO:0006012,GO:0008150,GO:0008152,GO:0019318,GO:0044238,GO:0044281,GO:0071704 2.7.1.6 ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00554,M00632 R01092 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko04147 - - - GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg k141_11943_1 218284.CCDN010000001_gene60 4.07e-121 356.0 COG0044@1|root,COG0044@2|Bacteria,1TPQM@1239|Firmicutes,4HA90@91061|Bacilli,1ZAS7@1386|Bacillus 91061|Bacilli F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily pyrC GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 k141_14340_1 218284.CCDN010000003_gene2974 1.28e-113 338.0 COG3583@1|root,COG3584@1|root,COG3583@2|Bacteria,COG3584@2|Bacteria,1TTIK@1239|Firmicutes,4HC79@91061|Bacilli,1ZC0Q@1386|Bacillus 91061|Bacilli T protein conserved in bacteria yabE - - - - - - - - - - - 3D,DUF348,G5 k141_8416_2 1042377.AFPJ01000024_gene701 3.36e-78 237.0 COG1863@1|root,COG1863@2|Bacteria,1MZYJ@1224|Proteobacteria,1S7Z3@1236|Gammaproteobacteria,468HN@72275|Alteromonadaceae 1236|Gammaproteobacteria P Na+/H+ ion antiporter subunit mnhE - - ko:K05569 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - MNHE k141_8416_3 1042377.AFPJ01000024_gene700 5.55e-39 134.0 295H6@1|root,2ZSUT@2|Bacteria,1P6Q1@1224|Proteobacteria,1SUBY@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_26230_2 717605.Theco_1714 1.05e-20 89.7 COG0207@1|root,COG0207@2|Bacteria,1TSIR@1239|Firmicutes,4H9QS@91061|Bacilli,26T1B@186822|Paenibacillaceae 91061|Bacilli F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis thyA GO:0003674,GO:0003824,GO:0004799,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0032259,GO:0034641,GO:0034654,GO:0042083,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046385,GO:0046483,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 - - - Thymidylat_synt k141_2467_1 1042377.AFPJ01000051_gene90 2.24e-99 293.0 COG3148@1|root,COG3148@2|Bacteria,1N8XY@1224|Proteobacteria,1RS6H@1236|Gammaproteobacteria,467NU@72275|Alteromonadaceae 1236|Gammaproteobacteria S DTW yfiP - - ko:K05812 - - - - ko00000 - - - DTW k141_19078_1 665959.HMPREF1013_02628 2.36e-56 176.0 COG0526@1|root,COG0526@2|Bacteria,1VAS6@1239|Firmicutes,4HKGM@91061|Bacilli,1ZHAS@1386|Bacillus 91061|Bacilli CO Thioredoxin ytpP GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - - - - - - - - - - Thioredoxin k141_22677_1 218284.CCDN010000001_gene1493 1.4e-42 145.0 COG1174@1|root,COG1174@2|Bacteria,1UHWH@1239|Firmicutes,4ISE5@91061|Bacilli,1ZS6F@1386|Bacillus 91061|Bacilli E Binding-protein-dependent transport system inner membrane component - - - ko:K05846 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - BPD_transp_1 k141_22677_2 1123405.AUMM01000063_gene1666 2.17e-35 135.0 COG1125@1|root,COG1125@2|Bacteria,1TPV8@1239|Firmicutes,4H9SI@91061|Bacilli,26NQ3@186821|Sporolactobacillaceae 91061|Bacilli E ATPases associated with a variety of cellular activities - - - ko:K05847 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - ABC_tran,CBS k141_32149_1 471874.PROSTU_01097 3.87e-05 42.7 2DNPH@1|root,32YF1@2|Bacteria,1NARM@1224|Proteobacteria,1TEB6@1236|Gammaproteobacteria,3ZA81@586|Providencia 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_90_1 218284.CCDN010000001_gene665 1.53e-72 239.0 COG0608@1|root,COG0608@2|Bacteria,1TPXE@1239|Firmicutes,4H9UP@91061|Bacilli,1ZBAT@1386|Bacillus 91061|Bacilli L Single-stranded-DNA-specific exonuclease RecJ recJ - - ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1,ssDNA-exonuc_C k141_8418_2 1042377.AFPJ01000024_gene698 9.74e-35 120.0 COG1722@1|root,COG1722@2|Bacteria,1N72V@1224|Proteobacteria,1SC7N@1236|Gammaproteobacteria,468UE@72275|Alteromonadaceae 1236|Gammaproteobacteria L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseB GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494 3.1.11.6 ko:K03602 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_S k141_3646_1 42565.FP66_03090 2.66e-147 421.0 COG0006@1|root,COG0006@2|Bacteria,1MWUT@1224|Proteobacteria,1RZSD@1236|Gammaproteobacteria,1XNGP@135619|Oceanospirillales 135619|Oceanospirillales E Creatinase/Prolidase N-terminal domain - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016812,GO:0019752,GO:0032787,GO:0042399,GO:0042400,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046700,GO:0071704,GO:0072329,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.4.13.9,3.5.4.44 ko:K01271,ko:K15783 ko00260,ko01100,map00260,map01100 - R09800 RC02661 ko00000,ko00001,ko01000,ko01002 - - - Creatinase_N,Peptidase_M24 k141_4835_2 218284.CCDN010000005_gene3169 1.8e-33 115.0 2DQFN@1|root,336J9@2|Bacteria,1VJ6N@1239|Firmicutes,4HQ0A@91061|Bacilli,1ZK3U@1386|Bacillus 91061|Bacilli S Sporulation protein YhaL yhaL - - - - - - - - - - - Spore_YhaL k141_4835_3 218284.CCDN010000005_gene3168 1.76e-182 510.0 COG3481@1|root,COG3481@2|Bacteria,1TPIU@1239|Firmicutes,4HB1M@91061|Bacilli,1ZB1G@1386|Bacillus 91061|Bacilli L Shows a 3'-5' exoribonuclease activity yhaM GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031123,GO:0031125,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - ko:K03698 - - - - ko00000,ko01000,ko03019 - - - HD,tRNA_anti-codon k141_29774_1 1294265.JCM21738_2878 4.54e-81 260.0 COG0768@1|root,COG0768@2|Bacteria,1TQHY@1239|Firmicutes,4HAFX@91061|Bacilli,1ZBJM@1386|Bacillus 91061|Bacilli M penicillin-binding protein pbpA - - ko:K21465 ko00550,map00550 - - - ko00000,ko00001,ko01011 - - - PBP_dimer,Transpeptidase k141_29774_2 665959.HMPREF1013_02300 4.46e-54 178.0 COG0226@1|root,COG0226@2|Bacteria,1TQ5X@1239|Firmicutes,4HBEB@91061|Bacilli,1ZB22@1386|Bacillus 91061|Bacilli P Phosphate pstS GO:0003674,GO:0005488,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015698,GO:0042301,GO:0043167,GO:0043168,GO:0051179,GO:0051234 - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - PBP_like_2 k141_28613_2 1274524.BSONL12_04539 2.02e-119 349.0 2EJAN@1|root,33D1T@2|Bacteria,1VPTN@1239|Firmicutes,4I8KV@91061|Bacilli,1ZJBQ@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_28613_3 1274524.BSONL12_04574 1.14e-56 179.0 2DYNB@1|root,34AF5@2|Bacteria,1TZKM@1239|Firmicutes,4I8VS@91061|Bacilli,1ZIFS@1386|Bacillus 91061|Bacilli S Helix-turn-helix of insertion element transposase - - - - - - - - - - - - HTH_Tnp_1_2 k141_35734_1 1453501.JELR01000002_gene132 1.15e-273 789.0 COG0591@1|root,COG0784@1|root,COG4191@1|root,COG0591@2|Bacteria,COG0784@2|Bacteria,COG4191@2|Bacteria,1QTSW@1224|Proteobacteria,1T1G2@1236|Gammaproteobacteria,46D5M@72275|Alteromonadaceae 1236|Gammaproteobacteria T PAS fold - - - - - - - - - - - - HATPase_c,HisKA,PAS_4,PAS_7,Response_reg,SSF k141_33355_1 1348635.BBJY01000003_gene3748 8.51e-148 427.0 COG2706@1|root,COG2706@2|Bacteria,1MWGS@1224|Proteobacteria,1RNX2@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate - - 3.1.1.31 ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R02035 RC00537 ko00000,ko00001,ko00002,ko01000 - - - Lactonase k141_33355_3 298386.PBPRA2528 5.68e-17 79.0 2DK54@1|root,32UEC@2|Bacteria,1N1A8@1224|Proteobacteria,1SBNN@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_33355_5 1082933.MEA186_13642 5.67e-97 285.0 COG3791@1|root,COG3791@2|Bacteria,1RCXS@1224|Proteobacteria,2U814@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Glutathione-dependent formaldehyde-activating - - - - - - - - - - - - - k141_15542_2 421052.F945_00572 5.78e-87 270.0 COG1018@1|root,COG1018@2|Bacteria,1MU6E@1224|Proteobacteria,1RNA4@1236|Gammaproteobacteria,3NJUK@468|Moraxellaceae 1236|Gammaproteobacteria C 2Fe-2S iron-sulfur cluster binding domain - - - ko:K03863 ko00627,ko01120,map00627,map01120 - R05274 RC00392,RC01533 ko00000,ko00001 - - - FAD_binding_6,Fer2,NAD_binding_1 k141_15542_3 1232683.ADIMK_1147 3.01e-197 553.0 COG4638@1|root,COG4638@2|Bacteria,1MV2G@1224|Proteobacteria,1RQ8W@1236|Gammaproteobacteria,46A0H@72275|Alteromonadaceae 1236|Gammaproteobacteria P Rieske [2Fe-2S] domain vanA - 1.14.13.82 ko:K03862 ko00627,ko01120,map00627,map01120 - R05274 RC00392,RC01533 ko00000,ko00001,ko01000 - - - Rieske k141_15542_4 1232683.ADIMK_1148 1.6e-99 296.0 COG1802@1|root,COG1802@2|Bacteria,1NWSI@1224|Proteobacteria,1S2B4@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator vanR - - ko:K11475 - - - - ko00000,ko03000 - - - FCD,GntR k141_15542_5 1116375.VEJY3_17186 3.47e-192 536.0 COG0583@1|root,COG0583@2|Bacteria,1QYAP@1224|Proteobacteria,1RYE8@1236|Gammaproteobacteria,1XU6I@135623|Vibrionales 135623|Vibrionales K COG0583 Transcriptional regulator - - - ko:K21699 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate k141_15542_6 1116375.VEJY3_17191 0.0 937.0 COG2986@1|root,COG2986@2|Bacteria,1MU6K@1224|Proteobacteria,1RP02@1236|Gammaproteobacteria,1XUPB@135623|Vibrionales 135623|Vibrionales E Histidine ammonia-lyase hutH GO:0003674,GO:0003824,GO:0004397,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016840,GO:0016841,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564 4.3.1.3 ko:K01745 ko00340,ko01100,map00340,map01100 M00045 R01168 RC00361 ko00000,ko00001,ko00002,ko01000 - - - Lyase_aromatic k141_15542_7 1116375.VEJY3_17196 7.28e-149 436.0 COG2987@1|root,COG2987@2|Bacteria,1MU4W@1224|Proteobacteria,1RP89@1236|Gammaproteobacteria,1XTBK@135623|Vibrionales 135623|Vibrionales H Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate hutU GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016153,GO:0016829,GO:0016835,GO:0016836,GO:0019439,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0052803,GO:0052805,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 4.2.1.49 ko:K01712 ko00340,ko01100,map00340,map01100 M00045 R02914 RC00804 ko00000,ko00001,ko00002,ko01000 - - - Urocanase,Urocanase_C,Urocanase_N k141_23824_1 1116375.VEJY3_20531 1.7e-122 363.0 2AFXB@1|root,3160U@2|Bacteria,1RI5S@1224|Proteobacteria,1S87Z@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_23824_2 1116375.VEJY3_20536 1.69e-126 367.0 2DW4J@1|root,33YHV@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k141_23824_3 1116375.VEJY3_20551 1.58e-115 333.0 COG1309@1|root,COG1309@2|Bacteria,1RAAJ@1224|Proteobacteria,1SYKH@1236|Gammaproteobacteria,1Y2DV@135623|Vibrionales 135623|Vibrionales K Bacterial transcriptional repressor C-terminal - - - - - - - - - - - - TetR_C_13,TetR_N k141_23824_4 1116375.VEJY3_20556 2.1e-164 464.0 COG1902@1|root,COG1902@2|Bacteria,1MVIX@1224|Proteobacteria,1RMFI@1236|Gammaproteobacteria,1XSZS@135623|Vibrionales 135623|Vibrionales C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family xenB - - - - - - - - - - - Oxidored_FMN k141_25010_1 1116375.VEJY3_02475 2.19e-221 613.0 COG0287@1|root,COG1605@1|root,COG0287@2|Bacteria,COG1605@2|Bacteria,1MVUT@1224|Proteobacteria,1RQB3@1236|Gammaproteobacteria,1XUE1@135623|Vibrionales 135623|Vibrionales E T-protein tyrA - 1.3.1.12,5.4.99.5 ko:K14187 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00024,M00025 R01715,R01728 RC00125,RC03116 ko00000,ko00001,ko00002,ko01000 - - - CM_2,PDH k141_25010_2 1116375.VEJY3_02470 1.17e-246 678.0 COG0722@1|root,COG0722@2|Bacteria,1MU5Q@1224|Proteobacteria,1RMAA@1236|Gammaproteobacteria,1XSXX@135623|Vibrionales 135623|Vibrionales E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) aroF - 2.5.1.54 ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 - - - DAHP_synth_1 k141_25010_3 1116375.VEJY3_02465 5e-226 624.0 COG1472@1|root,COG1472@2|Bacteria,1MVAJ@1224|Proteobacteria,1RMQF@1236|Gammaproteobacteria,1XU7E@135623|Vibrionales 135623|Vibrionales G Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides nagZ GO:0000270,GO:0003674,GO:0003824,GO:0004553,GO:0004563,GO:0006022,GO:0006807,GO:0008150,GO:0008152,GO:0009254,GO:0009273,GO:0009987,GO:0015929,GO:0016787,GO:0016798,GO:0030203,GO:0042546,GO:0043170,GO:0044085,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901564 3.2.1.52 ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 M00628 R00022,R05963,R07809,R07810,R10831 RC00049 ko00000,ko00001,ko00002,ko01000 - - - Glyco_hydro_3 k141_25010_4 1116375.VEJY3_02460 2.63e-86 263.0 COG2377@1|root,COG2377@2|Bacteria,1MV4E@1224|Proteobacteria,1RNTZ@1236|Gammaproteobacteria,1XTEE@135623|Vibrionales 135623|Vibrionales F Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling anmK - 2.7.1.170 ko:K09001 - - - - ko00000,ko01000 - - - AnmK k141_11944_2 218284.CCDN010000008_gene4038 2.06e-13 69.7 COG2986@1|root,COG2986@2|Bacteria,1TPCW@1239|Firmicutes,4H9YS@91061|Bacilli,1ZC8Z@1386|Bacillus 91061|Bacilli E Histidine ammonia-lyase hutH - 4.3.1.3 ko:K01745 ko00340,ko01100,map00340,map01100 M00045 R01168 RC00361 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU39350 Lyase_aromatic k141_7178_1 1042377.AFPJ01000019_gene2537 0.0 964.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RNBD@1236|Gammaproteobacteria,46642@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec k141_16938_2 1116375.VEJY3_07695 2.08e-220 613.0 COG4597@1|root,COG4597@2|Bacteria,1MV0S@1224|Proteobacteria,1RN6V@1236|Gammaproteobacteria,1XSEY@135623|Vibrionales 135623|Vibrionales P COG4597 ABC-type amino acid transport system, permease component aapQ - - ko:K09970 ko02010,map02010 M00232 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.18,3.A.1.3.7,3.A.1.3.8 - - BPD_transp_1 k141_12225_2 218284.CCDN010000001_gene81 1.15e-109 319.0 COG3879@1|root,COG3879@2|Bacteria,1V2J7@1239|Firmicutes,4HG14@91061|Bacilli,1ZDER@1386|Bacillus 91061|Bacilli S protein conserved in bacteria ylxX GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - - - - - - - - - - DUF881 k141_26550_1 1196031.ALEG01000033_gene3010 8.78e-262 735.0 COG1472@1|root,COG1472@2|Bacteria,1TP63@1239|Firmicutes,4HBDB@91061|Bacilli,1ZCGR@1386|Bacillus 91061|Bacilli G Belongs to the glycosyl hydrolase 3 family ybbD - 3.2.1.52 ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 M00628 R00022,R05963,R07809,R07810,R10831 RC00049 ko00000,ko00001,ko00002,ko01000 - - - Big_2,Glyco_hydro_3,Glyco_hydro_3_C,Gram_pos_anchor,SLH k141_4992_1 1279017.AQYJ01000023_gene3248 2.33e-100 295.0 COG3023@1|root,COG3023@2|Bacteria,1RDHU@1224|Proteobacteria,1S3PG@1236|Gammaproteobacteria,46701@72275|Alteromonadaceae 1236|Gammaproteobacteria V COG3023 Negative regulator of beta-lactamase expression ampD GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043170,GO:0044424,GO:0044464,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 3.5.1.28 ko:K01447,ko:K03806 - - R04112 RC00064,RC00141 ko00000,ko01000,ko01011 - - iAF1260.b0110,iB21_1397.B21_00108,iBWG_1329.BWG_0103,iEC55989_1330.EC55989_0103,iECBD_1354.ECBD_3509,iECB_1328.ECB_00109,iECDH10B_1368.ECDH10B_0090,iECDH1ME8569_1439.ECDH1ME8569_0104,iECD_1391.ECD_00109,iECIAI1_1343.ECIAI1_0107,iECO103_1326.ECO103_0110,iECO111_1330.ECO111_0111,iECO26_1355.ECO26_0112,iECSE_1348.ECSE_0110,iECW_1372.ECW_m0107,iEKO11_1354.EKO11_3806,iETEC_1333.ETEC_0106,iEcDH1_1363.EcDH1_3492,iEcE24377_1341.EcE24377A_0112,iEcHS_1320.EcHS_A0114,iEcolC_1368.EcolC_3549,iJO1366.b0110,iSFV_1184.SFV_0101,iSF_1195.SF0107,iSFxv_1172.SFxv_0113,iS_1188.S0109,iUMNK88_1353.UMNK88_108,iWFL_1372.ECW_m0107,iY75_1357.Y75_RS00560 Amidase_2 k141_18156_1 218284.CCDN010000001_gene1145 1.94e-101 304.0 COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,4HA13@91061|Bacilli,1ZCMB@1386|Bacillus 91061|Bacilli E Aminotransferase aspB GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769,GO:0047297 2.6.1.1,2.6.1.14 ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 - R00355,R00694,R00734,R00896,R01346,R02433,R02619,R05052 RC00006,RC00025 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 k141_25240_1 1042377.AFPJ01000032_gene2774 5.67e-65 199.0 COG3671@1|root,COG3671@2|Bacteria,1MZMW@1224|Proteobacteria,1SF8E@1236|Gammaproteobacteria,46CD6@72275|Alteromonadaceae 1236|Gammaproteobacteria S membrane - - - - - - - - - - - - - k141_6327_1 666686.B1NLA3E_15770 3.59e-88 264.0 COG1961@1|root,COG1961@2|Bacteria,1V51N@1239|Firmicutes,4HDX2@91061|Bacilli,1ZQD1@1386|Bacillus 91061|Bacilli L Resolvase, N terminal domain - - - - - - - - - - - - Resolvase k141_368_1 700512.G8CTD0_9CAUD 4.51e-61 210.0 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QKNE@10699|Siphoviridae 10699|Siphoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 - - - - - - - - - - - k141_26551_1 574375.BAGA_18890 4.71e-75 236.0 2DB75@1|root,2Z7JY@2|Bacteria,1TSI8@1239|Firmicutes,4IRVK@91061|Bacilli,1ZJU4@1386|Bacillus 91061|Bacilli S Phage major capsid protein E - - - - - - - - - - - - Phage_cap_E k141_20400_2 1294265.JCM21738_3842 8.01e-216 605.0 COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HA2G@91061|Bacilli,1ZBE5@1386|Bacillus 91061|Bacilli IQ Activates fatty acids by binding to coenzyme A lcfB_2 - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding,AMP-binding_C k141_13389_5 1535422.ND16A_3283 1.11e-117 367.0 COG0823@1|root,COG3710@1|root,COG0823@2|Bacteria,COG3710@2|Bacteria,1RIFT@1224|Proteobacteria,1S7XY@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Transcriptional regulatory protein, C terminal - - - - - - - - - - - - PD40,Trans_reg_C k141_22873_1 1461580.CCAS010000093_gene4429 1.91e-72 229.0 COG4974@1|root,COG4974@2|Bacteria,1UA9R@1239|Firmicutes,4HFKY@91061|Bacilli,1ZE7N@1386|Bacillus 91061|Bacilli L Belongs to the 'phage' integrase family - - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_5,Phage_integrase k141_16939_2 1177181.T9A_00996 5.9e-114 333.0 2C8XG@1|root,2Z7PK@2|Bacteria,1RA5I@1224|Proteobacteria,1S82H@1236|Gammaproteobacteria,1XJE4@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF4197) - - - - - - - - - - - - DUF4197 k141_369_1 218284.CCDN010000002_gene2360 2.46e-62 198.0 COG0583@1|root,COG0583@2|Bacteria,1TQ6Y@1239|Firmicutes,4HB94@91061|Bacilli,1ZBXV@1386|Bacillus 91061|Bacilli K Transcriptional regulator ywbI GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:1901363,GO:1990837 - - - - - - - - - - HTH_1,LysR_substrate k141_33527_1 1294265.JCM21738_1673 6.01e-141 400.0 COG2211@1|root,COG2211@2|Bacteria,1UZQT@1239|Firmicutes,4HEAM@91061|Bacilli,1ZEM0@1386|Bacillus 91061|Bacilli G Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 k141_20401_1 1042377.AFPJ01000043_gene864 1.18e-27 112.0 COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,1RMQE@1236|Gammaproteobacteria,464C0@72275|Alteromonadaceae 1236|Gammaproteobacteria J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs rnr GO:0000175,GO:0003674,GO:0003724,GO:0003824,GO:0004386,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008408,GO:0008997,GO:0009056,GO:0009057,GO:0009266,GO:0009409,GO:0009628,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016896,GO:0017111,GO:0019222,GO:0019439,GO:0034458,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - ko:K12573 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03016,ko03019 - - - HTH_12,OB_RNB,RNB,S1 k141_16940_1 218284.CCDN010000001_gene1408 1.65e-93 282.0 COG4086@1|root,COG4086@2|Bacteria,1TR2I@1239|Firmicutes,4HBVZ@91061|Bacilli,1ZD5H@1386|Bacillus 91061|Bacilli S Secreted protein ypuA - - - - - - - - - - - DUF1002 k141_18157_2 1279017.AQYJ01000026_gene245 4.59e-81 255.0 COG0596@1|root,COG0596@2|Bacteria,1R6KU@1224|Proteobacteria,1RZA4@1236|Gammaproteobacteria 1236|Gammaproteobacteria S hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_4 k141_28854_1 1116375.VEJY3_21916 5.75e-126 361.0 COG1651@1|root,COG1651@2|Bacteria,1NUE9@1224|Proteobacteria,1SNTP@1236|Gammaproteobacteria,1XT8N@135623|Vibrionales 135623|Vibrionales O COG0526 Thiol-disulfide isomerase and thioredoxins - - - - - - - - - - - - Thioredoxin_4 k141_28854_2 223926.28808714 1.12e-96 285.0 COG2885@1|root,COG2885@2|Bacteria,1P1AB@1224|Proteobacteria,1RMCQ@1236|Gammaproteobacteria,1XVTB@135623|Vibrionales 135623|Vibrionales M Belongs to the ompA family - - - - - - - - - - - - OmpA k141_28854_3 674977.VMC_17060 8.66e-70 211.0 COG0695@1|root,COG0695@2|Bacteria,1N0IY@1224|Proteobacteria,1SA4G@1236|Gammaproteobacteria,1XY0M@135623|Vibrionales 135623|Vibrionales O COG0695 Glutaredoxin and related proteins - - - - - - - - - - - - GST_N_3,Glutaredoxin k141_28854_4 223926.28808716 2.52e-90 268.0 2A3K4@1|root,30S36@2|Bacteria,1QK1F@1224|Proteobacteria,1TI3Z@1236|Gammaproteobacteria,1XYBH@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_28854_5 1116375.VEJY3_21896 6.22e-114 328.0 COG4681@1|root,COG4681@2|Bacteria,1RDR9@1224|Proteobacteria,1S43N@1236|Gammaproteobacteria,1XWNR@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria - - - - - - - - - - - - YaeQ k141_28854_6 1219076.N646_4614 1.67e-44 144.0 COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,1XYCD@135623|Vibrionales 135623|Vibrionales K Cold shock cspV - - ko:K03704 - - - - ko00000,ko03000 - - - CSD k141_28854_7 223926.28808719 4.4e-28 103.0 COG3036@1|root,COG3036@2|Bacteria,1NH0E@1224|Proteobacteria,1SGZX@1236|Gammaproteobacteria,1XZ24@135623|Vibrionales 135623|Vibrionales S Domain of unknown function - - - ko:K09890 - - - - ko00000,ko03012 - - - DUF331 k141_28854_8 1116375.VEJY3_21881 6.47e-150 424.0 COG2834@1|root,COG2834@2|Bacteria,1MXW0@1224|Proteobacteria,1RS0K@1236|Gammaproteobacteria,1XVD7@135623|Vibrionales 135623|Vibrionales M Outer membrane lipoprotein-sorting protein VPA0557 - - - - - - - - - - - LolA_like k141_28854_9 1116375.VEJY3_21876 6.92e-182 515.0 COG4591@1|root,COG4591@2|Bacteria,1R4Q2@1224|Proteobacteria,1S1AK@1236|Gammaproteobacteria,1XVHA@135623|Vibrionales 135623|Vibrionales M FtsX-like permease family VPA0558 - - - - - - - - - - - FtsX,MacB_PCD k141_31211_1 935837.JAEK01000005_gene4333 2.91e-52 177.0 COG0189@1|root,COG0189@2|Bacteria,1TRXK@1239|Firmicutes,4HBN0@91061|Bacilli,1ZE4C@1386|Bacillus 91061|Bacilli HJ YheC/D like ATP-grasp - - 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 - R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - ATPgrasp_YheCD,Mur_ligase_C,Mur_ligase_M k141_6328_1 1042377.AFPJ01000043_gene895 7.66e-78 239.0 COG0583@1|root,COG0583@2|Bacteria,1QYAP@1224|Proteobacteria,1RYE8@1236|Gammaproteobacteria,46591@72275|Alteromonadaceae 1236|Gammaproteobacteria K Bacterial regulatory helix-turn-helix protein, lysR family - - - ko:K21699 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate k141_6328_2 1042377.AFPJ01000043_gene893 2.77e-28 105.0 2EFYJ@1|root,339QQ@2|Bacteria,1NH5C@1224|Proteobacteria,1SGE6@1236|Gammaproteobacteria,468WH@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_16941_1 288000.BBta_4831 0.000324 48.9 COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,2TS14@28211|Alphaproteobacteria 28211|Alphaproteobacteria E ABC-type dipeptide transport system periplasmic component - - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 k141_37056_1 1046714.AMRX01000001_gene1774 1.25e-27 125.0 COG5544@1|root,COG5544@2|Bacteria,1QU58@1224|Proteobacteria,1RYPH@1236|Gammaproteobacteria,465GU@72275|Alteromonadaceae 1236|Gammaproteobacteria S Lipoprotein - - - - - - - - - - - - - k141_37056_2 983545.Glaag_3230 0.000581 51.2 28IXC@1|root,2Z8V9@2|Bacteria,1R9RH@1224|Proteobacteria,1RQHP@1236|Gammaproteobacteria,467ZE@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - BBP2_2 k141_37056_3 1120970.AUBZ01000003_gene166 4.14e-79 248.0 COG0489@1|root,COG0489@2|Bacteria,1MVI9@1224|Proteobacteria,1RNB0@1236|Gammaproteobacteria,4649B@72275|Alteromonadaceae 1236|Gammaproteobacteria D COG0489 ATPases involved in chromosome partitioning - - 2.7.10.1 ko:K08252 - - - - ko00000,ko01000 - - - AAA_31 k141_37056_4 1120970.AUBZ01000003_gene167 8.26e-156 461.0 COG3206@1|root,COG3206@2|Bacteria,1MVBX@1224|Proteobacteria,1RXY8@1236|Gammaproteobacteria,465VX@72275|Alteromonadaceae 1236|Gammaproteobacteria M protein involved in exopolysaccharide biosynthesis - - - - - - - - - - - - GNVR,Wzz k141_37056_5 1328313.DS2_04860 5.05e-89 268.0 COG1596@1|root,COG1596@2|Bacteria,1RFBH@1224|Proteobacteria,1S35N@1236|Gammaproteobacteria,464WW@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG1596 Periplasmic protein involved in polysaccharide export wza - - ko:K01991 ko02026,map02026 - - - ko00000,ko00001,ko02000 1.B.18 - - Poly_export,SLBB k141_37056_6 983545.Glaag_3226 1.57e-132 398.0 COG2148@1|root,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,1RMMN@1236|Gammaproteobacteria,464MI@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG2148 Sugar transferases involved in lipopolysaccharide synthesis lthA - - - - - - - - - - - Bac_transf,CoA_binding_3 k141_37056_7 1121935.AQXX01000128_gene1852 3.19e-113 335.0 COG0726@1|root,COG0726@2|Bacteria,1MWMZ@1224|Proteobacteria,1RREJ@1236|Gammaproteobacteria,1XN90@135619|Oceanospirillales 135619|Oceanospirillales G Domain of unknown function (DUF3473) - - - - - - - - - - - - DUF3473,Polysacc_deac_1 k141_37056_8 754436.JCM19237_3647 1.64e-176 501.0 COG2348@1|root,COG2348@2|Bacteria,1MXFY@1224|Proteobacteria,1T22W@1236|Gammaproteobacteria 1236|Gammaproteobacteria V TIGRFAM FemAB-related protein, PEP-CTERM system-associated - - - - - - - - - - - - Acetyltransf_6 k141_37056_9 314285.KT71_09787 3.05e-52 181.0 COG0438@1|root,COG0438@2|Bacteria,1MVIM@1224|Proteobacteria,1RPB8@1236|Gammaproteobacteria,1J518@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_4 k141_34736_1 42565.FP66_14605 1.8e-81 248.0 COG2974@1|root,COG2974@2|Bacteria,1MXPR@1224|Proteobacteria,1RMNN@1236|Gammaproteobacteria,1XK25@135619|Oceanospirillales 135619|Oceanospirillales L May be involved in recombination rdgC - - ko:K03554 - - - - ko00000,ko03400 - - - RdgC k141_34736_2 42565.FP66_14600 9.31e-13 66.6 COG0204@1|root,COG0204@2|Bacteria,1MUFH@1224|Proteobacteria,1RNJQ@1236|Gammaproteobacteria,1XHR5@135619|Oceanospirillales 135619|Oceanospirillales I Acyltransferase - - - - - - - - - - - - Acyltransferase k141_370_1 1461580.CCAS010000043_gene3344 8.31e-59 195.0 COG4191@1|root,COG4191@2|Bacteria,1TSPI@1239|Firmicutes,4HCVV@91061|Bacilli,1ZE31@1386|Bacillus 91061|Bacilli T GHKL domain - - 2.7.13.3 ko:K07697 ko02020,map02020 M00485 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - 5TM-5TMR_LYT,HATPase_c,HisKA k141_1415_1 1185876.BN8_05234 3.31e-58 186.0 COG2323@1|root,COG2323@2|Bacteria,4NR3N@976|Bacteroidetes,47QT3@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF421) - - - - - - - - - - - - DUF421 k141_27546_1 545693.BMQ_1068 2.29e-120 355.0 COG1055@1|root,COG1055@2|Bacteria,1TPNN@1239|Firmicutes,4H9WV@91061|Bacilli,1ZBHC@1386|Bacillus 91061|Bacilli P Involved in arsenical resistance. Thought to form the channel of an arsenite pump ywrK - - ko:K03893 - - - - ko00000,ko02000 2.A.45.1,3.A.4.1 - - ArsB k141_27546_2 1499685.CCFJ01000041_gene930 1.82e-15 75.1 COG0363@1|root,COG0363@2|Bacteria,1TP10@1239|Firmicutes,4HAG4@91061|Bacilli,1ZD28@1386|Bacillus 91061|Bacilli G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion nagB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 3.5.99.6 ko:K02564 ko00520,ko01100,map00520,map01100 - R00765 RC00163 ko00000,ko00001,ko01000 - - iYO844.BSU35020 Glucosamine_iso k141_28855_1 218284.CCDN010000005_gene3365 5.09e-101 308.0 COG1032@1|root,COG1032@2|Bacteria,1TPGT@1239|Firmicutes,4HA0Y@91061|Bacilli,1ZAU7@1386|Bacillus 91061|Bacilli C Fe-S oxidoreductase bchE - 1.21.98.3 ko:K04034 ko00860,ko01100,ko01110,map00860,map01100,map01110 - R06268,R06269,R06270 RC00741,RC01491,RC01492 ko00000,ko00001,ko01000 - - - B12-binding,DUF4080,Radical_SAM k141_33528_2 1453501.JELR01000001_gene1943 2.02e-44 157.0 COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,1RNYI@1236|Gammaproteobacteria,4642M@72275|Alteromonadaceae 1236|Gammaproteobacteria M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxD GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 ko:K02536 ko00540,ko01100,map00540,map01100 M00060 R04550 RC00039,RC00166 ko00000,ko00001,ko00002,ko01000,ko01005 - - ic_1306.c0216 Hexapep,Hexapep_2,LpxD k141_12229_1 218284.CCDN010000002_gene2238 3.77e-138 394.0 COG3279@1|root,COG3279@2|Bacteria,1V14X@1239|Firmicutes,4HDIC@91061|Bacilli,1ZC3U@1386|Bacillus 91061|Bacilli T COG3279 Response regulator of the LytR AlgR family - - - ko:K07705 ko02020,map02020 M00492 - - ko00000,ko00001,ko00002,ko02022 - - - LytTR,Response_reg k141_12229_2 218284.CCDN010000002_gene2237 1.36e-17 83.2 COG3275@1|root,COG3275@2|Bacteria,1VTXF@1239|Firmicutes,4H9Z1@91061|Bacilli,1ZBKQ@1386|Bacillus 91061|Bacilli T Histidine kinase lytS - 2.7.13.3 ko:K07704 ko02020,map02020 M00492 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - 5TM-5TMR_LYT,GAF_3,HATPase_c,His_kinase k141_4995_1 1294265.JCM21738_27 7.61e-106 315.0 COG1686@1|root,COG1686@2|Bacteria,1TQN0@1239|Firmicutes,4HBCE@91061|Bacilli,1ZB0W@1386|Bacillus 91061|Bacilli M Belongs to the peptidase S11 family dacF GO:0003674,GO:0003824,GO:0004175,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.16.4 ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - PBP5_C,Peptidase_S11 k141_10961_2 218284.CCDN010000008_gene4188 5.05e-99 298.0 COG2081@1|root,COG2081@2|Bacteria,1TQ6E@1239|Firmicutes,4HAAT@91061|Bacilli,1ZAT3@1386|Bacillus 91061|Bacilli S HI0933-like protein ytfP - - ko:K07007 - - - - ko00000 - - - HI0933_like k141_22904_1 672.VV93_v1c23710 2.26e-08 57.4 COG4962@1|root,COG4962@2|Bacteria,1R7EN@1224|Proteobacteria,1RP9G@1236|Gammaproteobacteria,1XSF1@135623|Vibrionales 135623|Vibrionales U COG4962 Flp pilus assembly protein, ATPase CpaF - - - ko:K02283 - - - - ko00000,ko02035,ko02044 - - - T2SSE k141_20417_2 218284.CCDN010000001_gene1011 4.98e-163 461.0 COG1902@1|root,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,4H9YM@91061|Bacilli,1ZB4D@1386|Bacillus 91061|Bacilli C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes namA GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 1.6.99.1 ko:K00354 - - R00282 RC00001 ko00000,ko01000 - - - Oxidored_FMN k141_2684_1 1042377.AFPJ01000021_gene2117 1.8e-27 112.0 COG2244@1|root,COG2244@2|Bacteria 2|Bacteria S polysaccharide biosynthetic process - - - - - - - - - - - - MatE,Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C k141_26584_2 349521.HCH_04712 1.93e-122 358.0 COG0639@1|root,COG0639@2|Bacteria,1QE1Y@1224|Proteobacteria,1RRG9@1236|Gammaproteobacteria,1XHU1@135619|Oceanospirillales 1236|Gammaproteobacteria T Diadenosine tetraphosphatase and related serine threonine protein - - - - - - - - - - - - AAA_33,Metallophos,PNKP-ligase_C,PNKP_ligase k141_8611_2 1385511.N783_09245 4.25e-11 61.6 COG0410@1|root,COG0410@2|Bacteria,1TPW4@1239|Firmicutes,4HABJ@91061|Bacilli,2Y96A@289201|Pontibacillus 91061|Bacilli E Branched-chain amino acid ABC transporter ATP-binding protein - - - ko:K01996 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran k141_3901_1 1347369.CCAD010000065_gene3819 2.38e-54 181.0 COG2199@1|root,COG3706@2|Bacteria,1V9Y7@1239|Firmicutes,4HCVM@91061|Bacilli,1ZE91@1386|Bacillus 91061|Bacilli T Diguanylate cyclase, GGDEF domain - - - ko:K20971 ko02025,map02025 - - - ko00000,ko00001,ko01001,ko02022 - - - 7TMR-DISMED2,7TMR-DISM_7TM,GGDEF k141_33543_1 1246484.D479_00355 4.8e-27 105.0 2AUKD@1|root,31K93@2|Bacteria,1V6PK@1239|Firmicutes,4HHBG@91061|Bacilli,3NEMX@45667|Halobacillus 91061|Bacilli S Stage II sporulation protein R (spore_II_R) spoIIR - - ko:K06387 - - - - ko00000 - - - Spore_II_R k141_12249_1 218284.CCDN010000004_gene3058 5.98e-145 413.0 29SV9@1|root,30E1E@2|Bacteria,1V46E@1239|Firmicutes,4HI7R@91061|Bacilli,1ZD35@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_12249_2 218284.CCDN010000004_gene3059 1.01e-42 149.0 COG0772@1|root,COG0772@2|Bacteria,1TPGH@1239|Firmicutes,4HAV4@91061|Bacilli,1ZBSB@1386|Bacillus 91061|Bacilli D Belongs to the SEDS family rodA - - ko:K05837 - - - - ko00000,ko03036 - - - FTSW_RODA_SPOVE k141_24021_1 491952.Mar181_0237 3.03e-62 199.0 COG1176@1|root,COG1176@2|Bacteria,1MVGM@1224|Proteobacteria,1RNNZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria P ABC-type spermidine putrescine transport system, permease component I - - - ko:K11071 ko02010,map02010 M00299 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 - - BPD_transp_1 k141_24021_2 491952.Mar181_0236 4.65e-135 389.0 COG1177@1|root,COG1177@2|Bacteria,1MVC5@1224|Proteobacteria,1S1X9@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Binding-protein-dependent transport system inner membrane component - - - ko:K11070 ko02010,map02010 M00299 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 - - BPD_transp_1 k141_24021_3 686578.AFFX01000011_gene2526 2.63e-66 212.0 COG3191@1|root,COG3191@2|Bacteria,1MWDP@1224|Proteobacteria,1RYNM@1236|Gammaproteobacteria 1236|Gammaproteobacteria EQ peptidase S58 DmpA dmpA - 3.4.11.19 ko:K01266 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S58 k141_37067_1 218284.CCDN010000002_gene2849 1.88e-81 250.0 COG0697@1|root,COG0697@2|Bacteria,1TRKE@1239|Firmicutes,4HF69@91061|Bacilli,1ZQ3B@1386|Bacillus 91061|Bacilli EG EamA-like transporter family - - - - - - - - - - - - EamA k141_22905_1 1444310.JANV01000063_gene1934 8.81e-19 80.1 2E6I0@1|root,33158@2|Bacteria,1VIB0@1239|Firmicutes,4HNZB@91061|Bacilli,1ZJDR@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_22905_2 218284.CCDN010000002_gene2093 1.75e-147 423.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,1ZB7V@1386|Bacillus 91061|Bacilli I Belongs to the thiolase family pcaF - 2.3.1.174,2.3.1.223 ko:K02615 ko00360,ko01120,map00360,map01120 - R00829,R09839 RC00004,RC00326,RC03003 ko00000,ko00001,ko01000 - - - Thiolase_C,Thiolase_N k141_6342_1 861299.J421_2945 3.79e-46 171.0 COG1196@1|root,COG1196@2|Bacteria,1ZSY1@142182|Gemmatimonadetes 142182|Gemmatimonadetes D Required for chromosome condensation and partitioning smc - - ko:K03529 - - - - ko00000,ko03036 - - - SMC_N,SMC_hinge k141_32285_2 218284.CCDN010000006_gene3552 4.42e-138 393.0 COG0745@1|root,COG0745@2|Bacteria,1TP9M@1239|Firmicutes,4IPXG@91061|Bacilli,1ZRED@1386|Bacillus 91061|Bacilli KT Transcriptional regulatory protein, C terminal - - - - - - - - - - - - Response_reg,Trans_reg_C k141_32285_3 441769.ABFU01000060_gene587 5.27e-18 79.7 COG1672@1|root,COG1672@2|Bacteria,1U9TR@1239|Firmicutes,4IK15@91061|Bacilli,1ZJPC@1386|Bacillus 91061|Bacilli S Electron transfer DM13 - - - - - - - - - - - - DM13 k141_18178_1 1453501.JELR01000002_gene1358 1.75e-79 246.0 COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,1RMBT@1236|Gammaproteobacteria,4642P@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG1194 A G-specific DNA glycosylase mutY GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - ko:K03575 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD,NUDIX_4 k141_18178_2 1279017.AQYJ01000027_gene1978 3.01e-53 167.0 COG2924@1|root,COG2924@2|Bacteria,1MZ2V@1224|Proteobacteria,1S964@1236|Gammaproteobacteria,467W6@72275|Alteromonadaceae 1236|Gammaproteobacteria CO Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes yggX GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0033554,GO:0034599,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0070887 - - - - - - - - - - Iron_traffic k141_26585_1 1042377.AFPJ01000005_gene2435 4.81e-191 546.0 COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,1RMVN@1236|Gammaproteobacteria,464V8@72275|Alteromonadaceae 1236|Gammaproteobacteria M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source glmS - 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 - R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 - - - GATase_6,SIS k141_25258_3 1453501.JELR01000001_gene3239 3.43e-60 189.0 2EDVS@1|root,337QX@2|Bacteria,1NEZW@1224|Proteobacteria,1SCKV@1236|Gammaproteobacteria,46C7E@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_35895_2 218284.CCDN010000001_gene1080 2.75e-53 174.0 COG1408@1|root,COG1408@2|Bacteria,1V494@1239|Firmicutes,4HH1B@91061|Bacilli,1ZBFW@1386|Bacillus 91061|Bacilli S Calcineurin-like phosphoesterase superfamily domain ypbG - - ko:K07098 - - - - ko00000 - - - Metallophos,Metallophos_2 k141_16968_1 1385514.N782_00150 7.36e-41 155.0 COG2273@1|root,COG2273@2|Bacteria,1TR5U@1239|Firmicutes,4HB9D@91061|Bacilli,2YB4A@289201|Pontibacillus 91061|Bacilli G PFAM glycoside hydrolase family 16 - - - - - - - - - - - - CBM_4_9,Glyco_hydro_16,SLH k141_12438_1 218284.CCDN010000002_gene2181 9.19e-141 416.0 COG1502@1|root,COG1502@2|Bacteria,1VSU5@1239|Firmicutes,4HTP4@91061|Bacilli,1ZJTB@1386|Bacillus 91061|Bacilli I Lamin Tail Domain - - - - - - - - - - - - LTD,PLDc_2 k141_20571_1 1294265.JCM21738_515 5.48e-59 184.0 COG4326@1|root,COG4326@2|Bacteria,1VHE9@1239|Firmicutes,4HP75@91061|Bacilli,1ZJ9B@1386|Bacillus 91061|Bacilli S SpoOM protein - - - ko:K06377 - - - - ko00000 - - - Spo0M k141_538_1 1116375.VEJY3_23836 3.3e-39 136.0 COG4604@1|root,COG4604@2|Bacteria,1QU78@1224|Proteobacteria,1RP3Y@1236|Gammaproteobacteria,1XVHH@135623|Vibrionales 135623|Vibrionales P abc transporter atp-binding protein - - 3.6.3.34 ko:K02013 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 - - ABC_tran k141_538_2 1116375.VEJY3_23866 6.98e-74 221.0 COG0251@1|root,COG0251@2|Bacteria,1MZ5K@1224|Proteobacteria,1S5WM@1236|Gammaproteobacteria,1XXB5@135623|Vibrionales 135623|Vibrionales J translation initiation inhibitor, yjgF family - - - - - - - - - - - - Ribonuc_L-PSP k141_538_3 1116375.VEJY3_23886 1.14e-191 533.0 COG0583@1|root,COG0583@2|Bacteria,1MVGZ@1224|Proteobacteria,1RRFH@1236|Gammaproteobacteria,1XWES@135623|Vibrionales 135623|Vibrionales K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_21816_1 42565.FP66_01280 1.19e-34 126.0 COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,1RNCA@1236|Gammaproteobacteria,1XHF8@135619|Oceanospirillales 135619|Oceanospirillales E serine acetyltransferase cysE - 2.3.1.30 ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 M00021 R00586 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,SATase_N k141_11164_1 1453501.JELR01000002_gene902 2e-202 568.0 COG3517@1|root,COG3517@2|Bacteria,1MU5C@1224|Proteobacteria,1RNP7@1236|Gammaproteobacteria,464MV@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria impC - - ko:K11900 ko02025,map02025 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - VipB k141_28947_1 1500890.JQNL01000001_gene1412 1.31e-58 200.0 COG0471@1|root,COG0490@1|root,COG0471@2|Bacteria,COG0490@2|Bacteria,1MU0K@1224|Proteobacteria,1RMI1@1236|Gammaproteobacteria,1X4FF@135614|Xanthomonadales 135614|Xanthomonadales P Potassium transporter TrkA sac1 - - - - - - - - - - - CitMHS,TrkA_C k141_18335_2 1453501.JELR01000001_gene2141 1.82e-18 85.9 COG1506@1|root,COG1506@2|Bacteria,1MUJ3@1224|Proteobacteria,1RRN4@1236|Gammaproteobacteria,465BC@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases pqqM - - - - - - - - - - - PD40,Peptidase_S9 k141_12474_1 218284.CCDN010000011_gene4412 1.88e-133 383.0 COG1266@1|root,COG1266@2|Bacteria,1UZGJ@1239|Firmicutes,4HFCB@91061|Bacilli,1ZBE1@1386|Bacillus 91061|Bacilli S CAAX protease self-immunity ydiL - - ko:K07052 - - - - ko00000 - - - Abi k141_4074_1 218284.CCDN010000001_gene217 4.48e-190 529.0 COG2801@1|root,COG2801@2|Bacteria,1TQQY@1239|Firmicutes,4HC8M@91061|Bacilli,1ZBTR@1386|Bacillus 91061|Bacilli L PFAM Integrase catalytic region - - - ko:K07497 - - - - ko00000 - - - HTH_21,HTH_28,rve,rve_2 k141_26792_1 1343740.M271_26160 9.09e-25 100.0 COG0640@1|root,COG0640@2|Bacteria,2IIA5@201174|Actinobacteria 201174|Actinobacteria K Helix-turn-helix domain - - - - - - - - - - - - HTH_20 k141_11165_1 1279017.AQYJ01000027_gene1683 6.29e-137 421.0 COG5013@1|root,COG5013@2|Bacteria,1MW9S@1224|Proteobacteria,1RQ27@1236|Gammaproteobacteria,465D5@72275|Alteromonadaceae 1236|Gammaproteobacteria C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family narG GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009898,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0031235,GO:0032991,GO:0042126,GO:0043436,GO:0043546,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0097159,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098803,GO:1901363,GO:1902494,GO:1990204,GO:2001057 1.7.5.1 ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 M00529,M00530,M00804 R00798,R01106,R09497 RC02812 ko00000,ko00001,ko00002,ko01000 5.A.3.1 - iSBO_1134.SBO_1842,iUMN146_1321.UM146_09685 Molybdopterin,Molydop_binding,Nitr_red_alph_N k141_32418_1 1177154.Y5S_01704 6.94e-26 112.0 COG1361@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4932@2|Bacteria,1R5G4@1224|Proteobacteria,1SEWA@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Domain of unknown function DUF11 - - - - - - - - - - - - DUF11,SdrD_B k141_7519_1 42565.FP66_14295 7.46e-64 196.0 COG1677@1|root,COG1677@2|Bacteria,1N6RZ@1224|Proteobacteria,1SD52@1236|Gammaproteobacteria,1XKZR@135619|Oceanospirillales 135619|Oceanospirillales N Flagellar hook-basal body complex protein FliE fliE - - ko:K02408 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FliE k141_7519_2 1166948.JPZL01000001_gene2116 1.11e-09 55.8 COG1334@1|root,COG1334@2|Bacteria,1NH9T@1224|Proteobacteria 1224|Proteobacteria N flagellar protein FlaG flaG - - ko:K06603 - - - - ko00000,ko02035 - - - FlaG k141_27633_1 1294265.JCM21738_661 6.94e-147 417.0 COG0755@1|root,COG0755@2|Bacteria,1U8IP@1239|Firmicutes,4HD6H@91061|Bacilli,1ZBFP@1386|Bacillus 91061|Bacilli O cytochrome C hemX GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008152,GO:0015886,GO:0016020,GO:0044464,GO:0051179,GO:0051181,GO:0051234,GO:0055114,GO:0071702,GO:0071705,GO:0071944,GO:1901678 - ko:K02497 - - - - ko00000 - - - Cytochrom_C_asm k141_27633_2 1294265.JCM21738_662 3.44e-69 210.0 COG0373@1|root,COG0373@2|Bacteria,1TQN9@1239|Firmicutes,4HAVC@91061|Bacilli,1ZBER@1386|Bacillus 91061|Bacilli H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) hemA - 1.2.1.70 ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R04109 RC00055,RC00149 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS08420 GlutR_N,GlutR_dimer,Shikimate_DH k141_8820_2 997296.PB1_06797 6.4e-29 114.0 COG1066@1|root,COG1066@2|Bacteria,1TQ7Y@1239|Firmicutes,4H9YC@91061|Bacilli,1ZB8H@1386|Bacillus 91061|Bacilli O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function radA - - ko:K04485 - - - - ko00000,ko03400 - - - AAA_25,ATPase,ChlI k141_33761_1 42565.FP66_07580 9.03e-153 430.0 COG0336@1|root,COG0336@2|Bacteria,1MUN1@1224|Proteobacteria,1RMWC@1236|Gammaproteobacteria,1XHIU@135619|Oceanospirillales 135619|Oceanospirillales J Belongs to the RNA methyltransferase TrmD family trmD - 2.1.1.228 ko:K00554 - - R00597 RC00003,RC00334 ko00000,ko01000,ko03016 - - - tRNA_m1G_MT k141_20595_1 218284.CCDN010000001_gene1694 1.58e-135 395.0 COG2239@1|root,COG2239@2|Bacteria,1TP4V@1239|Firmicutes,4HASP@91061|Bacilli,1ZCSG@1386|Bacillus 91061|Bacilli P Acts as a magnesium transporter mgtE - - ko:K06213 - - - - ko00000,ko02000 1.A.26.1 - iYO844.BSU13300 CBS,MgtE,MgtE_N k141_11166_1 218284.CCDN010000002_gene2596 3.62e-41 149.0 COG4191@1|root,COG4191@2|Bacteria,1UZ9W@1239|Firmicutes,4HDK2@91061|Bacilli,1ZD85@1386|Bacillus 91061|Bacilli T Histidine kinase kinB - 2.7.13.3 ko:K07697 ko02020,map02020 M00485 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - 5TM-5TMR_LYT,HATPase_c,HisKA k141_26793_1 1294265.JCM21738_4685 6.69e-108 318.0 COG0491@1|root,COG0491@2|Bacteria,1U9UR@1239|Firmicutes,4HCI8@91061|Bacilli,1ZAQ9@1386|Bacillus 91061|Bacilli S Metallo-beta-lactamase superfamily fprA1 - - - - - - - - - - - Lactamase_B k141_23107_1 1279017.AQYJ01000024_gene942 4.02e-85 270.0 COG0477@1|root,COG2814@2|Bacteria,1MVSC@1224|Proteobacteria,1S029@1236|Gammaproteobacteria,465C0@72275|Alteromonadaceae 1236|Gammaproteobacteria EGP Major facilitator superfamily - - - - - - - - - - - - MFS_1 k141_23107_2 1279017.AQYJ01000024_gene941 4.21e-79 239.0 COG0454@1|root,COG0456@2|Bacteria,1RH71@1224|Proteobacteria,1S5XH@1236|Gammaproteobacteria,467WX@72275|Alteromonadaceae 1236|Gammaproteobacteria K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1 k141_18337_1 877418.ATWV01000002_gene1144 3.24e-76 252.0 COG0525@1|root,COG0525@2|Bacteria,2J659@203691|Spirochaetes 203691|Spirochaetes J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner valS - 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 k141_15861_1 223926.28809383 6.32e-218 603.0 COG1609@1|root,COG1609@2|Bacteria,1MVUR@1224|Proteobacteria,1RN2K@1236|Gammaproteobacteria,1XTVU@135623|Vibrionales 135623|Vibrionales K Ribose operon repressor rbsR - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 k141_15861_2 674977.VMC_00290 4.47e-202 561.0 COG0524@1|root,COG0524@2|Bacteria,1MV5B@1224|Proteobacteria,1RNVY@1236|Gammaproteobacteria,1XUEM@135623|Vibrionales 135623|Vibrionales H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway rbsK - 2.7.1.15 ko:K00852 ko00030,map00030 - R01051,R02750 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB k141_15861_3 1116375.VEJY3_18961 2.94e-72 224.0 COG1879@1|root,COG1879@2|Bacteria,1NRXG@1224|Proteobacteria,1RPBV@1236|Gammaproteobacteria,1XUF5@135623|Vibrionales 135623|Vibrionales G ABC-type sugar transport system, periplasmic component rbsB - - ko:K10439 ko02010,ko02030,map02010,map02030 M00212 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - Peripla_BP_4 k141_25455_1 1279017.AQYJ01000028_gene2137 3.36e-166 495.0 COG0308@1|root,COG0308@2|Bacteria,1PJTM@1224|Proteobacteria,1SYS3@1236|Gammaproteobacteria,4672R@72275|Alteromonadaceae 1236|Gammaproteobacteria E Peptidase family M1 domain - - 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - ERAP1_C,Peptidase_M1 k141_33762_1 1227488.C477_02910 2.2e-08 53.9 COG1917@1|root,arCOG02994@2157|Archaea,2XY1A@28890|Euryarchaeota,23WE5@183963|Halobacteria 183963|Halobacteria S conserved protein, contains double-stranded beta-helix domain - - - - - - - - - - - - Cupin_2 k141_33762_2 1385420.FRA_45c13260 1.13e-07 53.1 COG3703@1|root,COG3703@2|Bacteria,1RDNV@1224|Proteobacteria,1S9FZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides - - - - - - - - - - - - - k141_34893_1 1453501.JELR01000001_gene2248 3.25e-208 595.0 COG2871@1|root,COG3182@1|root,COG2871@2|Bacteria,COG3182@2|Bacteria,1QTUV@1224|Proteobacteria,1RNTI@1236|Gammaproteobacteria,464VZ@72275|Alteromonadaceae 1236|Gammaproteobacteria C 2Fe-2S iron-sulfur cluster binding domain - - - - - - - - - - - - FAD_binding_6,Fer2,NAD_binding_1,PepSY_TM k141_34893_2 1453501.JELR01000001_gene2249 1.46e-128 370.0 COG3182@1|root,COG3182@2|Bacteria,1R59B@1224|Proteobacteria,1S0MV@1236|Gammaproteobacteria,46DKY@72275|Alteromonadaceae 1236|Gammaproteobacteria S conserved secreted or membrane protein precursor - - - - - - - - - - - - PepSY_TM k141_34893_3 1453501.JELR01000001_gene2250 0.0 1539.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria,4651V@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec k141_34893_5 288000.BBta_p0130 1.58e-83 254.0 COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,2TSU8@28211|Alphaproteobacteria,3JWN3@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Polyphosphate kinase 2 (PPK2) - - 2.7.4.1 ko:K22468 ko00190,ko03018,map00190,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - PPK2 k141_30052_1 1042377.AFPJ01000028_gene2282 1.19e-61 211.0 COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,1RMU8@1236|Gammaproteobacteria,46404@72275|Alteromonadaceae 1236|Gammaproteobacteria G Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II algC GO:0003674,GO:0003824,GO:0004615,GO:0005975,GO:0008150,GO:0008152,GO:0016853,GO:0016866,GO:0016868,GO:0044238,GO:0071704 5.4.2.2,5.4.2.8 ko:K01840,ko:K15778 ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00114 R00959,R01057,R01818,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV k141_28949_1 1423321.AS29_05675 4.76e-95 288.0 COG0477@1|root,COG2814@2|Bacteria,1TRXM@1239|Firmicutes,4HCK1@91061|Bacilli,1ZPZJ@1386|Bacillus 91061|Bacilli EGP Major facilitator superfamily - - - - - - - - - - - - MFS_1,MFS_2 k141_26794_1 1294265.JCM21738_2117 1.05e-134 393.0 COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,4HAB3@91061|Bacilli,1ZAPP@1386|Bacillus 91061|Bacilli JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity dbpA - 3.6.4.13 ko:K05592 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,DbpA,Helicase_C k141_18338_1 218284.CCDN010000003_gene2968 1.54e-71 216.0 COG4467@1|root,COG4467@2|Bacteria,1VA1F@1239|Firmicutes,4HKND@91061|Bacilli,1ZGZH@1386|Bacillus 91061|Bacilli L Involved in initiation control of chromosome replication yabA GO:0003674,GO:0005488,GO:0005515,GO:0042802 - - - - - - - - - - YabB k141_24166_2 218284.CCDN010000001_gene1041 4.78e-160 457.0 COG0213@1|root,COG0213@2|Bacteria,1TPCH@1239|Firmicutes,4H9NP@91061|Bacilli,1ZBI1@1386|Bacillus 91061|Bacilli F phosphorylase pdp GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464 2.4.2.2 ko:K00756 ko00240,ko01100,map00240,map01100 - R01570,R01876,R02296,R02484 RC00063 ko00000,ko00001,ko01000 - - - Glycos_trans_3N,Glycos_transf_3,PYNP_C k141_9984_1 218284.CCDN010000002_gene2060 7.36e-111 332.0 COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,4H9SZ@91061|Bacilli,1ZAX7@1386|Bacillus 91061|Bacilli E Sodium alanine symporter - - - ko:K03310 - - - - ko00000 2.A.25 - - Na_Ala_symp k141_20596_1 1384054.N790_12220 1.78e-51 182.0 COG0471@1|root,COG3273@1|root,COG0471@2|Bacteria,COG3273@2|Bacteria,1MU0K@1224|Proteobacteria,1RMI1@1236|Gammaproteobacteria,1X4VE@135614|Xanthomonadales 135614|Xanthomonadales P Sodium:sulfate symporter transmembrane region - - - - - - - - - - - - CitMHS,Na_sulph_symp,TrkA_C k141_31304_1 1279017.AQYJ01000028_gene2336 3.8e-294 811.0 COG4579@1|root,COG4579@2|Bacteria,1MVRB@1224|Proteobacteria,1RMC2@1236|Gammaproteobacteria,4655G@72275|Alteromonadaceae 1236|Gammaproteobacteria F Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation aceK GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004721,GO:0005488,GO:0005524,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008772,GO:0009987,GO:0016208,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0017076,GO:0018105,GO:0018193,GO:0018209,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050790,GO:0065007,GO:0065009,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.11.5 ko:K00906 - - - - ko00000,ko01000 - - - AceK k141_561_1 1219076.N646_0128 4.09e-149 427.0 COG0754@1|root,COG0754@2|Bacteria,1MW6V@1224|Proteobacteria,1RQAP@1236|Gammaproteobacteria,1XTKG@135623|Vibrionales 135623|Vibrionales E Glutathionylspermidine synthase preATP-grasp - - - - - - - - - - - - GSP_synth k141_561_2 1116375.VEJY3_04965 1.55e-108 315.0 COG5463@1|root,COG5463@2|Bacteria,1RCVV@1224|Proteobacteria,1S3J0@1236|Gammaproteobacteria,1XWJZ@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF1190) - - - - - - - - - - - - DUF1190 k141_561_3 1280001.BAOA01000031_gene5164 3.39e-76 229.0 COG3766@1|root,COG3766@2|Bacteria,1N14W@1224|Proteobacteria,1S3T5@1236|Gammaproteobacteria,1XWWB@135623|Vibrionales 135623|Vibrionales S Domain of Unknown Function (DUF350) - - - ko:K08989 - - - - ko00000 - - - DUF350 k141_561_4 1116375.VEJY3_04955 3.98e-233 643.0 COG1226@1|root,COG1226@2|Bacteria,1NT9G@1224|Proteobacteria,1RZME@1236|Gammaproteobacteria,1XTBJ@135623|Vibrionales 135623|Vibrionales P COG1226 Kef-type K transport systems VP1064 - - ko:K10716 - - - - ko00000,ko02000 1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6 - - Ion_trans_2,TrkA_N k141_561_5 1219076.N646_0124 6.12e-256 701.0 COG0379@1|root,COG0379@2|Bacteria,1MWQU@1224|Proteobacteria,1RMFS@1236|Gammaproteobacteria,1XTIU@135623|Vibrionales 135623|Vibrionales H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate nadA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 ko:K03517 ko00760,ko01100,map00760,map01100 M00115 R04292 RC01119 ko00000,ko00001,ko00002,ko01000 - - - NadA k141_561_6 1280001.BAOA01000031_gene5161 2.71e-133 383.0 COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,1RQWA@1236|Gammaproteobacteria,1XSAP@135623|Vibrionales 135623|Vibrionales D Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division cpoB - - - - - - - - - - - TPR_16,TPR_6,TPR_8,TolA_bind_tri k141_6456_1 1294265.JCM21738_36 1.55e-72 218.0 COG0454@1|root,COG0456@2|Bacteria,1VAD7@1239|Firmicutes,4HKR2@91061|Bacilli,1ZHDK@1386|Bacillus 91061|Bacilli K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases ribT - - ko:K02859 - - - - ko00000 - - - Acetyltransf_1,Acetyltransf_10 k141_6456_2 1294265.JCM21738_37 4.15e-118 338.0 COG1547@1|root,COG1547@2|Bacteria,1VBXA@1239|Firmicutes,4HMG9@91061|Bacilli,1ZH3U@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF309) ypuF - - ko:K09763 - - - - ko00000 - - - DUF309 k141_4076_2 218284.CCDN010000001_gene1252 1.44e-49 167.0 COG1228@1|root,COG1228@2|Bacteria,1TPNQ@1239|Firmicutes,4H9VP@91061|Bacilli,1ZBB1@1386|Bacillus 91061|Bacilli Q COG1228 Imidazolonepropionase and related amidohydrolases hutI - - - - - - - - - - - Amidohydro_1,Amidohydro_3 k141_35999_1 1117647.M5M_07645 2.58e-94 290.0 COG0791@1|root,COG0791@2|Bacteria,1R45H@1224|Proteobacteria,1RZDR@1236|Gammaproteobacteria,1J9G5@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M COG0791 Cell wall-associated hydrolases (invasion-associated proteins) - - - - - - - - - - - - NLPC_P60,N_NLPC_P60,SH3_6,SH3_7 k141_14660_1 218284.CCDN010000001_gene152 4.69e-109 325.0 COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,4HB3K@91061|Bacilli,1ZCJR@1386|Bacillus 91061|Bacilli C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes pdhD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyr_redox_2,Pyr_redox_dim k141_37217_1 1279017.AQYJ01000027_gene1988 4.08e-260 720.0 COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,1RMSR@1236|Gammaproteobacteria,465J7@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the peptidase S41A family ctpA - 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - PDZ_2,Peptidase_S41 k141_37217_3 1279017.AQYJ01000028_gene2129 1.86e-48 160.0 COG3247@1|root,COG3247@2|Bacteria,1RH69@1224|Proteobacteria,1SAIB@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Short repeat of unknown function (DUF308) - - - - - - - - - - - - DUF308 k141_33763_2 218284.CCDN010000001_gene648 4.52e-99 289.0 2DGQY@1|root,32U7R@2|Bacteria,1V83A@1239|Firmicutes,4HKRI@91061|Bacilli,1ZH9Y@1386|Bacillus 91061|Bacilli S BofC C-terminal domain bofC - - ko:K06318 - - - - ko00000 - - - BOFC_N,BofC_C k141_30053_1 641149.HMPREF9016_00688 4.76e-87 263.0 COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,2VHIC@28216|Betaproteobacteria,2KQJD@206351|Neisseriales 206351|Neisseriales E ABC transporter, ATP-binding protein - - - ko:K10010 ko02010,map02010 M00234 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3.10,3.A.1.3.14 - - ABC_tran k141_28950_2 1294265.JCM21738_4704 9.7e-40 132.0 COG5503@1|root,COG5503@2|Bacteria,1VEI7@1239|Firmicutes,4HNSK@91061|Bacilli,1ZIUI@1386|Bacillus 91061|Bacilli S Belongs to the UPF0356 family ykzG - - - - - - - - - - - DUF1447 k141_23108_2 218284.CCDN010000005_gene3301 4.54e-78 245.0 COG2239@1|root,COG2239@2|Bacteria,1TP4V@1239|Firmicutes,4HASP@91061|Bacilli,1ZCSG@1386|Bacillus 91061|Bacilli P Acts as a magnesium transporter mgtE - - ko:K06213 - - - - ko00000,ko02000 1.A.26.1 - - CBS,MgtE,MgtE_N k141_12478_1 997296.PB1_16779 9.6e-96 284.0 COG0745@1|root,COG0745@2|Bacteria,1TPWS@1239|Firmicutes,4H9KP@91061|Bacilli,1ZBGS@1386|Bacillus 91061|Bacilli T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain phoP - - ko:K07658 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C k141_32421_1 796606.BMMGA3_13295 7.59e-31 121.0 COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H9SA@91061|Bacilli,1ZD7B@1386|Bacillus 91061|Bacilli M COG0744 Membrane carboxypeptidase (penicillin-binding protein) pbp1B - 2.4.1.129 ko:K03693,ko:K12551 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase k141_2774_1 1279017.AQYJ01000020_gene1298 1.14e-24 104.0 COG0500@1|root,COG1073@1|root,COG1073@2|Bacteria,COG2226@2|Bacteria,1PA5F@1224|Proteobacteria,1RY7A@1236|Gammaproteobacteria,465B1@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway bioC GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008757,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0010340,GO:0016053,GO:0016740,GO:0016741,GO:0016787,GO:0016788,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032259,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0052689,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.197 ko:K02169 ko00780,ko01100,map00780,map01100 M00572 R09543 RC00003,RC00460 ko00000,ko00001,ko00002,ko01000 - - iECP_1309.ECP_0791,iSBO_1134.SBO_0664,iSFV_1184.SFV_0760,iSF_1195.SF0727,iSFxv_1172.SFxv_0792,iSSON_1240.SSON_0756,iS_1188.S0768,iSbBS512_1146.SbBS512_E2575 Methyltransf_11 k141_7520_1 1453501.JELR01000002_gene1324 1.73e-34 122.0 COG0848@1|root,COG0848@2|Bacteria,1RENY@1224|Proteobacteria,1S3TB@1236|Gammaproteobacteria,4681G@72275|Alteromonadaceae 1236|Gammaproteobacteria U Biopolymer transport protein ExbD/TolR - - - - - - - - - - - - ExbD k141_7520_2 1453501.JELR01000002_gene1325 4.41e-101 295.0 COG0848@1|root,COG0848@2|Bacteria,1RHI8@1224|Proteobacteria,1S6FK@1236|Gammaproteobacteria,467HF@72275|Alteromonadaceae 1236|Gammaproteobacteria U COG0848 Biopolymer transport protein - - - - - - - - - - - - ExbD k141_25456_1 218284.CCDN010000004_gene3152 5.25e-108 320.0 COG0189@1|root,COG0189@2|Bacteria,1U4ME@1239|Firmicutes,4HFD2@91061|Bacilli,1ZBNP@1386|Bacillus 91061|Bacilli HJ YheC/D like ATP-grasp yheC - - - - - - - - - - - ATPgrasp_YheCD k141_25456_2 218284.CCDN010000004_gene3153 3.18e-113 336.0 COG0189@1|root,COG0189@2|Bacteria,1V1EV@1239|Firmicutes,4HFNI@91061|Bacilli,1ZBM5@1386|Bacillus 91061|Bacilli HJ YheC/D like ATP-grasp - - - - - - - - - - - - ATPgrasp_YheCD k141_33764_1 747.DR93_899 3e-39 135.0 COG1943@1|root,COG1943@2|Bacteria,1MX19@1224|Proteobacteria,1RSJY@1236|Gammaproteobacteria,1Y8G3@135625|Pasteurellales 135625|Pasteurellales L Protein involved in DNA binding, transposase activity and transposition DNA-mediated - - - ko:K07491 - - - - ko00000 - - - Y1_Tnp k141_19458_1 935836.JAEL01000007_gene2897 6.34e-168 484.0 COG1620@1|root,COG1620@2|Bacteria,1TQNM@1239|Firmicutes,4HAF3@91061|Bacilli,1ZC0U@1386|Bacillus 91061|Bacilli C L-lactate permease - - - ko:K03303 - - - - ko00000,ko02000 2.A.14 - - Lactate_perm k141_30054_1 997296.PB1_08252 3.03e-54 170.0 COG1609@1|root,COG1609@2|Bacteria,1VADF@1239|Firmicutes,4HKIY@91061|Bacilli,1ZGY1@1386|Bacillus 91061|Bacilli K Stage III sporulation protein D spoIIID - - ko:K06283 - - - - ko00000,ko03000 - - - SpoIIID k141_34895_1 1116375.VEJY3_08380 8.7e-77 231.0 COG2153@1|root,COG2153@2|Bacteria,1QJZB@1224|Proteobacteria,1TI1S@1236|Gammaproteobacteria,1XY6B@135623|Vibrionales 135623|Vibrionales S Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_10 k141_34895_2 1116375.VEJY3_08385 8e-89 262.0 29YAY@1|root,30K56@2|Bacteria,1P8DZ@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_34910_1 187272.Mlg_1916 3.75e-93 281.0 COG0697@1|root,COG0697@2|Bacteria,1QWRA@1224|Proteobacteria,1T2X5@1236|Gammaproteobacteria,1WZKJ@135613|Chromatiales 135613|Chromatiales EG EamA-like transporter family - - - - - - - - - - - - EamA k141_10011_1 997296.PB1_05732 1.53e-20 92.0 2E8CD@1|root,332R0@2|Bacteria,1VJ26@1239|Firmicutes,4HQY4@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - k141_10011_2 1384057.CD33_06170 8.41e-15 72.8 2EPRI@1|root,33HC0@2|Bacteria,1VN2I@1239|Firmicutes,4HRIX@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - k141_32427_2 1453501.JELR01000001_gene3241 1.77e-35 132.0 COG0457@1|root,COG0457@2|Bacteria,1RC07@1224|Proteobacteria,1S36N@1236|Gammaproteobacteria,46864@72275|Alteromonadaceae 1236|Gammaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_8 k141_4090_1 218284.CCDN010000001_gene709 5.32e-87 260.0 COG1191@1|root,COG1191@2|Bacteria,1TPJ5@1239|Firmicutes,4HBY2@91061|Bacilli,1ZB3Q@1386|Bacillus 91061|Bacilli K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released sigK GO:0000003,GO:0000988,GO:0000990,GO:0003674,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043254,GO:0043934,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - ko:K03091 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4 k141_25470_1 1122201.AUAZ01000027_gene2209 1.48e-44 146.0 COG2963@1|root,COG2963@2|Bacteria,1N04F@1224|Proteobacteria,1S9BV@1236|Gammaproteobacteria,46815@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG2963 Transposase and inactivated derivatives - - - ko:K07483 - - - - ko00000 - - - HTH_Tnp_1 k141_25470_2 1190606.AJYG01000141_gene5 1.32e-136 392.0 COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,1RPEW@1236|Gammaproteobacteria,1XUGP@135623|Vibrionales 135623|Vibrionales L Transposase - - - ko:K07497 - - - - ko00000 - - - HTH_21,rve k141_1586_1 584708.Apau_0548 8.09e-77 250.0 COG0855@1|root,COG0855@2|Bacteria,3TAC8@508458|Synergistetes 508458|Synergistetes H Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) ppk - 2.7.4.1 ko:K00937 ko00190,ko03018,map00190,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - PP_kinase,PP_kinase_C,PP_kinase_N k141_19475_1 1007103.AFHW01000102_gene5410 3.42e-07 53.5 COG3869@1|root,COG3869@2|Bacteria,1TPBA@1239|Firmicutes,4HC6U@91061|Bacilli,26T89@186822|Paenibacillaceae 91061|Bacilli E Catalyzes the specific phosphorylation of arginine residues in proteins mcsB GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 ko:K19405 - - R11090 RC00002,RC00203 ko00000,ko01000 - - - ATP-gua_Ptrans k141_19475_2 265729.GS18_0215580 1.21e-10 62.0 COG3880@1|root,COG3880@2|Bacteria,1V6YM@1239|Firmicutes,4HH4R@91061|Bacilli,1ZG9T@1386|Bacillus 91061|Bacilli S protein with conserved CXXC pairs mcsA GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 - ko:K19411 - - - - ko00000 - - - UVR k141_27647_1 218284.CCDN010000001_gene194 2.11e-63 199.0 COG0602@1|root,COG0602@2|Bacteria,1TQ58@1239|Firmicutes,4HAJ3@91061|Bacilli,1ZBRU@1386|Bacillus 91061|Bacilli H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds queE GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008144,GO:0016829,GO:0016840,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:1901681,GO:1904047 4.3.99.3 ko:K10026 ko00790,ko01100,map00790,map01100 - R10002 RC02989 ko00000,ko00001,ko01000,ko03016 - - - Fer4_12,Fer4_14,Radical_SAM k141_27647_3 1308866.J416_11427 2.69e-07 50.8 COG0603@1|root,COG0603@2|Bacteria,1TP4Z@1239|Firmicutes,4HB1Y@91061|Bacilli,470B1@74385|Gracilibacillus 91061|Bacilli F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) queC - 6.3.4.20 ko:K06920 ko00790,ko01100,map00790,map01100 - R09978 RC00959 ko00000,ko00001,ko01000,ko03016 - - - QueC k141_23147_1 1453501.JELR01000005_gene1566 2.59e-98 306.0 COG4773@1|root,COG4773@2|Bacteria,1QTXJ@1224|Proteobacteria,1T2BS@1236|Gammaproteobacteria,46D8F@72275|Alteromonadaceae 1236|Gammaproteobacteria P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec k141_21845_1 1453501.JELR01000002_gene1381 0.0 1186.0 COG4774@1|root,COG4774@2|Bacteria,1NMCN@1224|Proteobacteria,1T3TQ@1236|Gammaproteobacteria,46DC7@72275|Alteromonadaceae 1236|Gammaproteobacteria P TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_11440_1 1235798.C817_01523 1.61e-59 192.0 COG1896@1|root,COG1896@2|Bacteria,1V3MK@1239|Firmicutes,24IBW@186801|Clostridia,27VN6@189330|Dorea 186801|Clostridia S HD domain - - - ko:K07023 - - - - ko00000 - - - HD_3 k141_19680_1 218284.CCDN010000011_gene4414 1.4e-101 309.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,4HA38@91061|Bacilli,1ZBKJ@1386|Bacillus 91061|Bacilli O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions groL GO:0001817,GO:0001819,GO:0001871,GO:0002791,GO:0002793,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009986,GO:0009987,GO:0016465,GO:0030246,GO:0030247,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044764,GO:0046812,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051082,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051704,GO:0061077,GO:0065007,GO:0070201,GO:0090087,GO:0098630,GO:0098743,GO:0101031,GO:1903530,GO:1903532,GO:1904951,GO:1990220,GO:2000482,GO:2000484,GO:2001065 - ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 - - - Cpn60_TCP1 k141_23288_1 1453501.JELR01000005_gene1573 1e-182 521.0 COG1538@1|root,COG1538@2|Bacteria,1MUHM@1224|Proteobacteria,1RNNS@1236|Gammaproteobacteria,469JV@72275|Alteromonadaceae 1236|Gammaproteobacteria MU Outer membrane efflux protein - - - - - - - - - - - - OEP k141_7665_1 649747.HMPREF0083_00446 1.7e-51 176.0 COG2199@1|root,COG3706@2|Bacteria,1V2QN@1239|Firmicutes,4HFY9@91061|Bacilli,26UGW@186822|Paenibacillaceae 91061|Bacilli T GGDEF domain yhcK1 - 2.7.7.65 ko:K18967 - - - - ko00000,ko01000,ko02000 9.B.34.1.1 - - 5TM-5TMR_LYT,GGDEF k141_11441_1 1122931.AUAE01000012_gene2212 1.93e-05 52.8 COG5545@1|root,COG5545@2|Bacteria,4NJ76@976|Bacteroidetes,2G30U@200643|Bacteroidia,231KG@171551|Porphyromonadaceae 976|Bacteroidetes S Domain of unknonw function from B. Theta Gene description (DUF3874) - - - - - - - - - - - - DUF3874,VirE,VirE_N k141_27004_1 1348635.BBJY01000003_gene3775 3.37e-114 338.0 COG1653@1|root,COG1653@2|Bacteria,1MVGS@1224|Proteobacteria,1RQFU@1236|Gammaproteobacteria,1XUX4@135623|Vibrionales 135623|Vibrionales G Bacterial extracellular solute-binding protein - - - - - - - - - - - - SBP_bac_8 k141_23289_1 331869.BAL199_30097 4.55e-12 65.1 COG1177@1|root,COG1177@2|Bacteria,1MVC5@1224|Proteobacteria,2TRRJ@28211|Alphaproteobacteria,4BPZD@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria E Binding-protein-dependent transport system inner membrane component - - - ko:K11070,ko:K11074 ko02010,map02010 M00299,M00300 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.1,3.A.1.11.2 - - BPD_transp_1 k141_23289_2 983920.Y88_1348 5.63e-51 172.0 COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQMJ@28211|Alphaproteobacteria,2K3GW@204457|Sphingomonadales 204457|Sphingomonadales E Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system potA - 3.6.3.31 ko:K11072,ko:K11076 ko02010,map02010 M00299,M00300 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.11.1,3.A.1.11.2 - - ABC_tran,TOBE_2 k141_24349_1 42565.FP66_07920 4.28e-161 472.0 COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,1RMQE@1236|Gammaproteobacteria,1XH6K@135619|Oceanospirillales 135619|Oceanospirillales J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs rnr - - ko:K12573 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03016,ko03019 - - - HTH_12,OB_RNB,RNB,S1 k141_17209_1 1453501.JELR01000005_gene1619 9.43e-32 122.0 COG0497@1|root,COG0497@2|Bacteria,1PAB3@1224|Proteobacteria,1RZB5@1236|Gammaproteobacteria,468PN@72275|Alteromonadaceae 1236|Gammaproteobacteria L DNA recombination - - - - - - - - - - - - - k141_17209_2 1453501.JELR01000005_gene1618 1.08e-110 337.0 2C1UX@1|root,33FGU@2|Bacteria,1NQE8@1224|Proteobacteria,1SJFD@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_17209_3 1453501.JELR01000005_gene1617 5.78e-71 221.0 COG1664@1|root,COG1664@2|Bacteria,1ND4H@1224|Proteobacteria,1SF92@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Polymer-forming cytoskeletal - - - - - - - - - - - - Bactofilin k141_11442_1 1294265.JCM21738_2332 1e-108 327.0 COG1620@1|root,COG1620@2|Bacteria,1TQNM@1239|Firmicutes,4HAF3@91061|Bacilli,1ZC0U@1386|Bacillus 91061|Bacilli C L-lactate permease - - - ko:K03303 - - - - ko00000,ko02000 2.A.14 - - Lactate_perm k141_33921_1 485915.Dret_0329 7.68e-55 184.0 COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,42PB7@68525|delta/epsilon subdivisions,2WJX5@28221|Deltaproteobacteria,2MA0E@213115|Desulfovibrionales 28221|Deltaproteobacteria M PFAM Cyclopropane-fatty-acyl-phospholipid synthase - - 2.1.1.79 ko:K00574 - - - - ko00000,ko01000 - - - CMAS k141_33921_2 1122611.KB903953_gene5710 1.07e-14 73.2 COG3576@1|root,COG3576@2|Bacteria,2GP9M@201174|Actinobacteria,4EIVW@85012|Streptosporangiales 201174|Actinobacteria S Pyridoxamine 5'-phosphate oxidase - - - ko:K07006 - - - - ko00000 - - - Putative_PNPOx k141_2924_1 1121929.KB898669_gene3230 5.24e-131 380.0 COG1309@1|root,COG1309@2|Bacteria,1V060@1239|Firmicutes,4HEDA@91061|Bacilli 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - TetR_N k141_5474_1 1279017.AQYJ01000020_gene1363 4.72e-57 185.0 COG1595@1|root,COG1595@2|Bacteria,1N748@1224|Proteobacteria,1SEDH@1236|Gammaproteobacteria,468VM@72275|Alteromonadaceae 1236|Gammaproteobacteria K ECF sigma factor - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_754_1 1116375.VEJY3_04285 1.04e-223 628.0 COG0318@1|root,COG0318@2|Bacteria,1MW0Y@1224|Proteobacteria,1RN35@1236|Gammaproteobacteria,1XTBP@135623|Vibrionales 135623|Vibrionales IQ O-succinylbenzoic acid--CoA ligase menE - 6.2.1.26 ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R04030 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - AMP-binding,AMP-binding_C k141_14810_1 1294265.JCM21738_4465 1.1e-53 170.0 COG0816@1|root,COG0816@2|Bacteria,1V6ER@1239|Firmicutes,4HH04@91061|Bacilli,1ZG6Y@1386|Bacillus 91061|Bacilli L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA yrrK GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - ko:K07447 - - - - ko00000,ko01000 - - - RuvX k141_14810_2 1294265.JCM21738_4464 1.05e-56 176.0 COG4472@1|root,COG4472@2|Bacteria,1VAC4@1239|Firmicutes,4HKD0@91061|Bacilli,1ZHU7@1386|Bacillus 91061|Bacilli S Belongs to the UPF0297 family yrzL - - - - - - - - - - - DUF965 k141_12684_1 1144325.PMI22_01314 3.93e-110 329.0 COG0654@1|root,COG0654@2|Bacteria,1RESU@1224|Proteobacteria 1224|Proteobacteria CH FAD binding domain - - 1.14.13.114 ko:K14974 ko00760,ko01120,map00760,map01120 M00622 R08764 RC00115 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_3 k141_12684_2 400668.Mmwyl1_3137 1.41e-133 389.0 COG0451@1|root,COG0451@2|Bacteria,1MU1A@1224|Proteobacteria,1SZ92@1236|Gammaproteobacteria,1XNMF@135619|Oceanospirillales 135619|Oceanospirillales M Polysaccharide biosynthesis protein - - - - - - - - - - - - Epimerase k141_12684_3 1208321.D104_14395 3.07e-134 382.0 COG2057@1|root,COG2057@2|Bacteria,1RA4V@1224|Proteobacteria,1RP21@1236|Gammaproteobacteria,1XHQF@135619|Oceanospirillales 135619|Oceanospirillales I transferase scoB - 2.8.3.5 ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 - R00410 RC00014 ko00000,ko00001,ko01000 - - - CoA_trans k141_19707_2 218284.CCDN010000011_gene4423 2.73e-105 327.0 COG1305@1|root,COG1305@2|Bacteria,1TP8K@1239|Firmicutes,4HB2E@91061|Bacilli,1ZBUN@1386|Bacillus 91061|Bacilli E COG1305 Transglutaminase-like enzymes yebA - - - - - - - - - - - DUF4129,Transglut_core k141_7687_1 218284.CCDN010000002_gene2596 3.48e-27 108.0 COG4191@1|root,COG4191@2|Bacteria,1UZ9W@1239|Firmicutes,4HDK2@91061|Bacilli,1ZD85@1386|Bacillus 91061|Bacilli T Histidine kinase kinB - 2.7.13.3 ko:K07697 ko02020,map02020 M00485 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - 5TM-5TMR_LYT,HATPase_c,HisKA k141_32585_1 218284.CCDN010000001_gene996 3.52e-156 445.0 COG4129@1|root,COG4129@2|Bacteria,1TP2T@1239|Firmicutes,4HAWV@91061|Bacilli,1ZBBI@1386|Bacillus 91061|Bacilli S Putative aromatic acid exporter C-terminal domain yqjA - - - - - - - - - - - ArAE_1,ArAE_1_C k141_32585_2 1196031.ALEG01000012_gene822 2.48e-39 134.0 COG1376@1|root,COG1376@2|Bacteria,1V26F@1239|Firmicutes,4HG56@91061|Bacilli,1ZGC7@1386|Bacillus 91061|Bacilli S protein conserved in bacteria yqjB - - - - - - - - - - - YkuD k141_27011_1 1294265.JCM21738_4055 1.8e-95 283.0 COG1191@1|root,COG1191@2|Bacteria,1TPDD@1239|Firmicutes,4H9MN@91061|Bacilli,1ZB53@1386|Bacillus 91061|Bacilli K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released sigG - - ko:K03091 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r3,Sigma70_r4 k141_27011_2 1294265.JCM21738_4082 8.04e-49 155.0 COG1873@1|root,COG1873@2|Bacteria,1VEMT@1239|Firmicutes,4HNT3@91061|Bacilli,1ZI0Y@1386|Bacillus 91061|Bacilli S sporulation protein ylmC - - - - - - - - - - - PRC k141_27793_2 1144343.PMI41_03171 1.03e-34 129.0 COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,2TR2Q@28211|Alphaproteobacteria,43HHC@69277|Phyllobacteriaceae 28211|Alphaproteobacteria V ABC transporter hndI GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0016020,GO:0044464,GO:0050896,GO:0071944 - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_23330_1 935836.JAEL01000004_gene2588 7.87e-87 263.0 COG0697@1|root,COG0697@2|Bacteria,1V2GJ@1239|Firmicutes,4HV8D@91061|Bacilli,1ZRP6@1386|Bacillus 91061|Bacilli EG EamA-like transporter family - - - - - - - - - - - - EamA k141_12702_1 218284.CCDN010000001_gene1229 1.73e-136 394.0 COG1876@1|root,COG1876@2|Bacteria,1V1F7@1239|Firmicutes,4HBR1@91061|Bacilli,1ZCAG@1386|Bacillus 91061|Bacilli M D-alanyl-D-alanine carboxypeptidase yodJ - 3.4.17.14 ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 M00651 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 - - - VanY k141_36170_1 1279017.AQYJ01000028_gene2404 1.76e-69 230.0 COG4772@1|root,COG4772@2|Bacteria,1MUIH@1224|Proteobacteria,1RQYX@1236|Gammaproteobacteria,46D6R@72275|Alteromonadaceae 1236|Gammaproteobacteria P TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_36170_2 1123279.ATUS01000001_gene1232 2.41e-89 273.0 COG1957@1|root,COG1957@2|Bacteria,1QYX6@1224|Proteobacteria,1T3WB@1236|Gammaproteobacteria,1JC35@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria F Protein of unknown function, DUF547 - - - - - - - - - - - - DUF547 k141_36170_3 1122194.AUHU01000015_gene2971 2.71e-150 449.0 COG4773@1|root,COG4773@2|Bacteria,1NXPR@1224|Proteobacteria,1RSBC@1236|Gammaproteobacteria,4657C@72275|Alteromonadaceae 1236|Gammaproteobacteria P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec k141_22015_1 1116375.VEJY3_13955 7.02e-138 392.0 COG3637@1|root,COG3637@2|Bacteria,1R3QN@1224|Proteobacteria,1RY3J@1236|Gammaproteobacteria,1XUQF@135623|Vibrionales 135623|Vibrionales M Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety SO3905 - - - - - - - - - - - OMP_b-brl k141_25728_1 1294265.JCM21738_1251 2.12e-131 382.0 COG2262@1|root,COG2262@2|Bacteria,1TNZB@1239|Firmicutes,4HACA@91061|Bacilli,1ZBT6@1386|Bacillus 91061|Bacilli S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis hflX - - ko:K03665 - - - - ko00000,ko03009 - - - GTP-bdg_M,GTP-bdg_N,MMR_HSR1 k141_9004_1 582402.Hbal_2502 9.26e-27 110.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MV8W@1224|Proteobacteria,2U0EP@28211|Alphaproteobacteria,43W6Q@69657|Hyphomonadaceae 28211|Alphaproteobacteria P TIGRFAM TonB-dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec k141_9004_2 1122194.AUHU01000013_gene696 5.37e-47 164.0 COG5434@1|root,COG5434@2|Bacteria,1MXP8@1224|Proteobacteria,1RRJZ@1236|Gammaproteobacteria,4644J@72275|Alteromonadaceae 1236|Gammaproteobacteria G Belongs to the glycosyl hydrolase 28 family - - - - - - - - - - - - Glyco_hydro_28 k141_23331_1 218284.CCDN010000001_gene1070 1.86e-112 332.0 COG4955@1|root,COG4955@2|Bacteria,1TQU9@1239|Firmicutes,4HFUR@91061|Bacilli,1ZDGR@1386|Bacillus 91061|Bacilli S protein conserved in bacteria ypbB - 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 - - - HTH_40,RQC k141_31390_1 1294265.JCM21738_1976 5.43e-49 158.0 2BAGI@1|root,323X4@2|Bacteria,1UARE@1239|Firmicutes,4IM44@91061|Bacilli,1ZJ3I@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3889) - - - - - - - - - - - - DUF3889 k141_31390_2 1294265.JCM21738_1975 1.16e-121 358.0 COG2719@1|root,COG2719@2|Bacteria,1TRHQ@1239|Firmicutes,4HBAW@91061|Bacilli,1ZAT5@1386|Bacillus 91061|Bacilli S Stage V sporulation protein R spoVR - - ko:K06415 - - - - ko00000 - - - SpoVR k141_25729_1 1395587.P364_0106595 6.94e-10 64.7 29SR4@1|root,30DX0@2|Bacteria,1V1H9@1239|Firmicutes,4HFRK@91061|Bacilli,275E4@186822|Paenibacillaceae 91061|Bacilli S Domain of unknown function (DUF4179) - - - - - - - - - - - - DUF4179 k141_24381_1 1042377.AFPJ01000012_gene1366 3.51e-110 326.0 COG0169@1|root,COG0169@2|Bacteria,1MVH4@1224|Proteobacteria,1RPB7@1236|Gammaproteobacteria,4647Q@72275|Alteromonadaceae 1236|Gammaproteobacteria E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) aroE GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_3165,iECOK1_1307.ECOK1_3701,iECS88_1305.ECS88_3669,iECUMN_1333.ECUMN_3755,iSBO_1134.SBO_3275,iUMN146_1321.UM146_16315,iUTI89_1310.UTI89_C3726 Shikimate_DH,Shikimate_dh_N k141_14821_1 218284.CCDN010000001_gene1294 1.32e-100 299.0 COG0053@1|root,COG0053@2|Bacteria,1TP5C@1239|Firmicutes,4HAP0@91061|Bacilli,1ZBSN@1386|Bacillus 91061|Bacilli P Dimerisation domain of Zinc Transporter cat - - - - - - - - - - - Cation_efflux,ZT_dimer k141_5496_1 1279017.AQYJ01000024_gene1004 3.23e-149 428.0 COG0697@1|root,COG0697@2|Bacteria,1PGSE@1224|Proteobacteria,1RMZY@1236|Gammaproteobacteria,4673D@72275|Alteromonadaceae 1236|Gammaproteobacteria EG EamA-like transporter family yhbE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - EamA k141_5496_2 1453501.JELR01000002_gene181 5.27e-208 577.0 COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,1RMUC@1236|Gammaproteobacteria,464JX@72275|Alteromonadaceae 1236|Gammaproteobacteria F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) prs GO:0000287,GO:0003674,GO:0003824,GO:0004749,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006015,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042301,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046391,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b1207,iAPECO1_1312.APECO1_323,iB21_1397.B21_01192,iBWG_1329.BWG_1032,iE2348C_1286.E2348C_1330,iEC042_1314.EC042_1264,iEC55989_1330.EC55989_1303,iECABU_c1320.ECABU_c14780,iECBD_1354.ECBD_2414,iECB_1328.ECB_01182,iECDH10B_1368.ECDH10B_1260,iECDH1ME8569_1439.ECDH1ME8569_1146,iECD_1391.ECD_01182,iECED1_1282.ECED1_1355,iECH74115_1262.ECH74115_1688,iECIAI1_1343.ECIAI1_1228,iECIAI39_1322.ECIAI39_1543,iECNA114_1301.ECNA114_1372,iECO103_1326.ECO103_1309,iECO111_1330.ECO111_1536,iECO26_1355.ECO26_1720,iECOK1_1307.ECOK1_1360,iECP_1309.ECP_1255,iECS88_1305.ECS88_1275,iECSE_1348.ECSE_1257,iECSF_1327.ECSF_1183,iECSP_1301.ECSP_1597,iECUMN_1333.ECUMN_1504,iECW_1372.ECW_m1293,iECs_1301.ECs1712,iEKO11_1354.EKO11_2647,iETEC_1333.ETEC_1311,iEcDH1_1363.EcDH1_2440,iEcE24377_1341.EcE24377A_1355,iEcHS_1320.EcHS_A1312,iEcSMS35_1347.EcSMS35_1935,iEcolC_1368.EcolC_2419,iG2583_1286.G2583_1478,iJO1366.b1207,iJR904.b1207,iLF82_1304.LF82_1744,iNRG857_1313.NRG857_06180,iSBO_1134.SBO_1860,iSDY_1059.SDY_1256,iSSON_1240.SSON_1971,iUMN146_1321.UM146_11025,iUMNK88_1353.UMNK88_1523,iUTI89_1310.UTI89_C1401,iWFL_1372.ECW_m1293,iY75_1357.Y75_RS06300,ic_1306.c1665 Pribosyl_synth,Pribosyltran_N k141_5496_3 1453501.JELR01000002_gene182 8.98e-117 338.0 COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,1S46A@1236|Gammaproteobacteria,466F7@72275|Alteromonadaceae 1236|Gammaproteobacteria J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ctc GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02897 ko03010,map03010 M00178 - - ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L25p,Ribosomal_TL5_C k141_5496_4 1453501.JELR01000002_gene183 3.39e-120 345.0 COG0193@1|root,COG0193@2|Bacteria,1MX1P@1224|Proteobacteria,1RPK3@1236|Gammaproteobacteria,46699@72275|Alteromonadaceae 1236|Gammaproteobacteria J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis pth GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006515,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019538,GO:0030163,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0052689,GO:0071704,GO:0140098,GO:0140101,GO:1901564,GO:1901565,GO:1901575 3.1.1.29 ko:K01056 - - - - ko00000,ko01000,ko03012 - - - Pept_tRNA_hydro k141_5496_5 1453501.JELR01000002_gene184 1.01e-250 689.0 COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,1RMBI@1236|Gammaproteobacteria,46586@72275|Alteromonadaceae 1236|Gammaproteobacteria J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner ychF GO:0003674,GO:0003824,GO:0004857,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030234,GO:0043021,GO:0043022,GO:0043023,GO:0043086,GO:0044092,GO:0044424,GO:0044464,GO:0044877,GO:0050790,GO:0050896,GO:0065007,GO:0065009,GO:0098772 - ko:K06942 - - - - ko00000,ko03009 - - - MMR_HSR1,YchF-GTPase_C k141_27794_1 1121936.AUHI01000006_gene1912 5.16e-75 237.0 COG2199@1|root,COG3706@2|Bacteria,1V2QN@1239|Firmicutes,4HFY9@91061|Bacilli 91061|Bacilli T GGDEF domain yhcK1 - 2.7.7.65 ko:K18967 - - - - ko00000,ko01000,ko02000 9.B.34.1.1 - - 5TM-5TMR_LYT,GGDEF k141_17240_1 1453501.JELR01000002_gene899 1.1e-75 243.0 COG3519@1|root,COG3519@2|Bacteria,1MUY4@1224|Proteobacteria,1RPK4@1236|Gammaproteobacteria,466BP@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria vasA - - ko:K11896 - M00334 - - ko00000,ko00002,ko02044 3.A.23.1 - - T6SS_TssF k141_17240_2 1279017.AQYJ01000027_gene1542 1.82e-16 74.3 COG3518@1|root,COG3518@2|Bacteria,1RG8W@1224|Proteobacteria,1S50E@1236|Gammaproteobacteria,4697Z@72275|Alteromonadaceae 1236|Gammaproteobacteria S Gene 25-like lysozyme - - - ko:K11897 - M00334 - - ko00000,ko00002,ko02044 - - - GPW_gp25 k141_16061_1 1280001.BAOA01000182_gene2897 5.64e-46 166.0 COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,1RPA0@1236|Gammaproteobacteria,1XTSQ@135623|Vibrionales 135623|Vibrionales L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD recD - 3.1.11.5 ko:K03581 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_30,UvrD_C_2 k141_16061_2 1116375.VEJY3_12340 0.0 1825.0 COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,1RPC6@1236|Gammaproteobacteria,1XTTM@135623|Vibrionales 135623|Vibrionales L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA recB - 3.1.11.5 ko:K03582 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - PDDEXK_1,UvrD-helicase,UvrD_C k141_32587_1 1453501.JELR01000002_gene1449 2.36e-72 219.0 COG0789@1|root,COG0789@2|Bacteria,1RITY@1224|Proteobacteria,1S61S@1236|Gammaproteobacteria,467YX@72275|Alteromonadaceae 1236|Gammaproteobacteria K helix_turn_helix, mercury resistance liuR - - - - - - - - - - - MerR,MerR-DNA-bind,MerR_1 k141_768_2 1116375.VEJY3_04130 1.89e-302 828.0 COG0397@1|root,COG0397@2|Bacteria,1MVK3@1224|Proteobacteria,1RNCS@1236|Gammaproteobacteria,1XSQA@135623|Vibrionales 135623|Vibrionales S Belongs to the UPF0061 (SELO) family - - - - - - - - - - - - UPF0061 k141_25730_1 1453501.JELR01000001_gene3170 1.82e-97 293.0 COG0628@1|root,COG0628@2|Bacteria,1MW0B@1224|Proteobacteria,1RPVP@1236|Gammaproteobacteria,465AI@72275|Alteromonadaceae 1236|Gammaproteobacteria S permease perM GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - ko:K03548 - - - - ko00000,ko02000 2.A.86.1 - - AI-2E_transport k141_2932_2 1219077.VAZ01S_021_00020 4.92e-188 531.0 COG0472@1|root,COG0472@2|Bacteria,1MWYW@1224|Proteobacteria,1RNAP@1236|Gammaproteobacteria,1XUZS@135623|Vibrionales 135623|Vibrionales M Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP- C55) wecA - 2.7.8.33,2.7.8.35 ko:K02851 - - R08856 RC00002 ko00000,ko01000,ko01003,ko01005 - - - Glycos_transf_4 k141_2932_3 1117318.PRUB_04946 4.92e-48 167.0 COG0463@1|root,COG0463@2|Bacteria,1QXD2@1224|Proteobacteria,1T387@1236|Gammaproteobacteria,2Q25F@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria M Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 k141_2932_4 595494.Tola_2861 2.29e-48 169.0 COG1216@1|root,COG1216@2|Bacteria,1QTEK@1224|Proteobacteria,1S5EC@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Pfam Glycosyl transferase family 2 rfbF - - ko:K12990 ko02024,ko02025,map02024,map02025 - - - ko00000,ko00001,ko01000,ko01003,ko01005 - GT2 - Glycos_transf_2 k141_2932_5 515622.bpr_I0387 2.29e-37 140.0 COG3307@1|root,COG3307@2|Bacteria,1TQIB@1239|Firmicutes,2496F@186801|Clostridia,4BZHA@830|Butyrivibrio 186801|Clostridia M TupA-like ATPgrasp - - - - - - - - - - - - ATPgrasp_TupA k141_2932_6 1219072.VHA01S_032_00080 1.95e-63 206.0 COG1216@1|root,COG1216@2|Bacteria,1N8UX@1224|Proteobacteria,1SD31@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF616) - - - - - - - - - - - - DUF616 k141_2932_7 1219072.VHA01S_032_00090 9.83e-75 242.0 2BSY5@1|root,32N1X@2|Bacteria,1NIII@1224|Proteobacteria,1SWG4@1236|Gammaproteobacteria 1236|Gammaproteobacteria S EpsG family - - - - - - - - - - - - EpsG k141_2932_8 391603.FBALC1_09327 3.95e-87 270.0 COG3307@1|root,COG3307@2|Bacteria,4NF1G@976|Bacteroidetes,1I0F8@117743|Flavobacteriia 976|Bacteroidetes M TupA-like ATPgrasp - - - - - - - - - - - - ATPgrasp_TupA k141_19709_2 240302.BN982_01872 4.66e-31 110.0 2E3WX@1|root,32YU3@2|Bacteria,1VFHJ@1239|Firmicutes,4HPQ5@91061|Bacilli,3NFC8@45667|Halobacillus 91061|Bacilli - - yozC - - - - - - - - - - - - k141_19709_3 1280390.CBQR020000025_gene580 9.86e-22 90.1 COG0400@1|root,COG0400@2|Bacteria,1TPBY@1239|Firmicutes,4HB45@91061|Bacilli,26QI2@186822|Paenibacillaceae 91061|Bacilli S Carboxylesterase yahD - - ko:K06999 - - - - ko00000 - - - Abhydrolase_2,DLH k141_6606_1 1453501.JELR01000002_gene858 0.0 994.0 COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,1RMYY@1236|Gammaproteobacteria,465WZ@72275|Alteromonadaceae 1236|Gammaproteobacteria M Mechanosensitive ion channel kefA - - - - - - - - - - - MS_channel k141_23333_1 218284.CCDN010000006_gene3659 2.82e-146 412.0 COG1896@1|root,COG1896@2|Bacteria,1TSDU@1239|Firmicutes,4HA8H@91061|Bacilli,1ZF42@1386|Bacillus 91061|Bacilli S HD containing hydrolase-like enzyme yfbR - - ko:K07023 - - - - ko00000 - - - HD_2 k141_22016_1 1403313.AXBR01000021_gene3112 2.76e-48 164.0 COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,4HAA6@91061|Bacilli,1ZCDY@1386|Bacillus 91061|Bacilli IQ reductase fabG GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - iYO844.BSU15910 adh_short_C2 k141_22016_2 314264.ROS217_21612 7.08e-16 78.6 COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,2TRTT@28211|Alphaproteobacteria,46PX6@74030|Roseovarius 28211|Alphaproteobacteria I Acyl-carrier-protein S-malonyltransferase fabD GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.39 ko:K00645 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082 R01626,R11671 RC00004,RC00039,RC02727 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyl_transf_1 k141_18582_1 1348635.BBJY01000014_gene936 1.23e-34 123.0 COG1280@1|root,COG1280@2|Bacteria,1RASZ@1224|Proteobacteria,1S56X@1236|Gammaproteobacteria,1XX3Q@135623|Vibrionales 135623|Vibrionales E threonine efflux protein - - - - - - - - - - - - LysE k141_18582_2 1348635.BBJY01000014_gene935 4.93e-180 503.0 COG2207@1|root,COG2207@2|Bacteria,1R3ZW@1224|Proteobacteria,1S2Y4@1236|Gammaproteobacteria,1XSP8@135623|Vibrionales 135623|Vibrionales K COG2207 AraC-type DNA-binding domain-containing proteins - - - - - - - - - - - - AraC_binding,HTH_18 k141_18582_3 314292.VAS14_03633 8.98e-81 247.0 COG2207@1|root,COG3449@1|root,COG2207@2|Bacteria,COG3449@2|Bacteria,1MWTF@1224|Proteobacteria,1RMKE@1236|Gammaproteobacteria,1XT8F@135623|Vibrionales 135623|Vibrionales K Bacterial transcription activator, effector binding domain - - - ko:K07506,ko:K13652 - - - - ko00000,ko03000 - - - GyrI-like,HTH_18 k141_18582_4 1136163.M565_ctg5P0004 5.48e-23 96.3 COG2207@1|root,COG3449@1|root,COG2207@2|Bacteria,COG3449@2|Bacteria,1MWTF@1224|Proteobacteria,1RMKE@1236|Gammaproteobacteria,1XT8F@135623|Vibrionales 135623|Vibrionales K Bacterial transcription activator, effector binding domain - - - ko:K07506,ko:K13652 - - - - ko00000,ko03000 - - - GyrI-like,HTH_18 k141_10290_1 1267534.KB906755_gene4333 2.45e-63 212.0 COG2377@1|root,COG2377@2|Bacteria,3Y3CU@57723|Acidobacteria,2JI1E@204432|Acidobacteriia 204432|Acidobacteriia O Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling anmK - 2.7.1.170 ko:K09001 - - - - ko00000,ko01000 - - - AnmK k141_7689_1 314292.VAS14_21131 1.12e-178 523.0 COG1629@1|root,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria,1XV5Z@135623|Vibrionales 135623|Vibrionales HP TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_30195_1 218284.CCDN010000002_gene2534 5.51e-121 353.0 COG0604@1|root,COG0604@2|Bacteria,1TT5J@1239|Firmicutes,4HCXG@91061|Bacilli,1ZBNX@1386|Bacillus 91061|Bacilli C alcohol dehydrogenase - - - - - - - - - - - - - k141_30195_2 935836.JAEL01000158_gene3971 2.4e-130 375.0 COG0662@1|root,COG0662@2|Bacteria,1V3H4@1239|Firmicutes,4HH1K@91061|Bacilli,1ZFFQ@1386|Bacillus 91061|Bacilli G Cupin domain yrkC - - - - - - - - - - - Cupin_2 k141_9005_1 234831.PSM_A0569 8.33e-55 184.0 COG3844@1|root,COG3844@2|Bacteria,1MUKN@1224|Proteobacteria,1RPY3@1236|Gammaproteobacteria,2Q41U@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria H Cys/Met metabolism PLP-dependent enzyme kynU - 3.7.1.3 ko:K01556 ko00380,ko01100,map00380,map01100 M00038 R00987,R02668,R03936 RC00284,RC00415 ko00000,ko00001,ko00002,ko01000 - - - Aminotran_5 k141_9005_2 1123053.AUDG01000055_gene2204 3.9e-59 197.0 COG1506@1|root,COG1506@2|Bacteria,1QWCQ@1224|Proteobacteria,1S38C@1236|Gammaproteobacteria 1236|Gammaproteobacteria E alpha/beta hydrolase fold - - - - - - - - - - - - Abhydrolase_3,Abhydrolase_6 k141_20761_1 1274524.BSONL12_04369 1.23e-103 313.0 COG0305@1|root,COG0305@2|Bacteria,1UYF2@1239|Firmicutes,4HF6Q@91061|Bacilli 91061|Bacilli L DnaB-like helicase C terminal domain - - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - AAA_25,DnaB_C k141_17242_1 240302.BN982_03582 3.61e-93 284.0 COG1916@1|root,COG1916@2|Bacteria,1TSWJ@1239|Firmicutes,4HANT@91061|Bacilli,3NDM9@45667|Halobacillus 91061|Bacilli S TraB family traB - - - - - - - - - - - TraB k141_18583_1 1453501.JELR01000005_gene1790 7.78e-78 243.0 COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,1RQJ9@1236|Gammaproteobacteria,4656M@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K03585 ko01501,ko01503,map01501,map01503 M00646,M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,8.A.1.6 - - HlyD_D23 k141_22017_1 1121859.KB890750_gene355 1.78e-15 77.0 COG0358@1|root,COG0358@2|Bacteria,4NENT@976|Bacteroidetes,47K9B@768503|Cytophagia 976|Bacteroidetes L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG - - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2 k141_32589_1 1403313.AXBR01000017_gene3635 1.37e-69 228.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1TQ85@1239|Firmicutes,4HAC0@91061|Bacilli,1ZR0Z@1386|Bacillus 91061|Bacilli EU Dienelactone hydrolase family - - - - - - - - - - - - PD40,Peptidase_S9,Peptidase_S9_N k141_33940_1 1131730.BAVI_22718 7.73e-100 295.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,4HBHP@91061|Bacilli,1ZECA@1386|Bacillus 91061|Bacilli C COG2086 Electron transfer flavoprotein, beta subunit - - - ko:K03521 - - - - ko00000 - - - ETF k141_27797_1 1121374.KB891576_gene236 4.57e-27 114.0 COG4774@1|root,COG4774@2|Bacteria,1NMCN@1224|Proteobacteria,1T1GZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria P receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_9258_2 1348635.BBJY01000027_gene2257 1.8e-153 434.0 COG3971@1|root,COG3971@2|Bacteria,1RA35@1224|Proteobacteria,1S589@1236|Gammaproteobacteria,1XVYV@135623|Vibrionales 135623|Vibrionales Q 2-keto-4-pentenoate hydratase - - 4.2.1.80 ko:K02554 ko00360,ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00360,map00362,map00621,map00622,map01100,map01120,map01220 M00545,M00569 R02601,R04781 RC00750,RC01213 br01602,ko00000,ko00001,ko00002,ko01000 - - - - k141_9258_3 1116375.VEJY3_19656 1.11e-236 661.0 COG0446@1|root,COG0607@1|root,COG0446@2|Bacteria,COG0607@2|Bacteria,1NR3M@1224|Proteobacteria,1T1WT@1236|Gammaproteobacteria,1XSS8@135623|Vibrionales 135623|Vibrionales P NAD(FAD)-dependent dehydrogenases cdr - - - - - - - - - - - Pyr_redox_2,Pyr_redox_dim,Rhodanese k141_35364_3 1453501.JELR01000001_gene3079 1.21e-34 119.0 COG5007@1|root,COG5007@2|Bacteria,1N1WJ@1224|Proteobacteria,1SCAR@1236|Gammaproteobacteria,468MC@72275|Alteromonadaceae 1236|Gammaproteobacteria K Belongs to the BolA IbaG family yrbA GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051536,GO:0051537,GO:0051540 - - - - - - - - - - BolA k141_35364_4 1279017.AQYJ01000024_gene1050 1.43e-144 416.0 COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,1RN91@1236|Gammaproteobacteria,46522@72275|Alteromonadaceae 1236|Gammaproteobacteria M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine murA GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008760,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R00660 RC00350 ko00000,ko00001,ko01000,ko01011 - - - EPSP_synthase k141_5698_1 218284.CCDN010000001_gene1147 1.19e-144 410.0 COG3935@1|root,COG3935@2|Bacteria,1V283@1239|Firmicutes,4HFP3@91061|Bacilli,1ZC34@1386|Bacillus 91061|Bacilli L DNA replication protein DnaD dnaD - - ko:K02086 - - - - ko00000 - - - DnaB_2,HTH_36 k141_907_2 945550.VISI1226_11756 1.51e-51 165.0 COG0073@1|root,COG0073@2|Bacteria,1QRBG@1224|Proteobacteria,1SNZX@1236|Gammaproteobacteria,1XXC4@135623|Vibrionales 135623|Vibrionales J Putative tRNA binding domain - - - ko:K06878 - - - - ko00000 - - - tRNA_bind k141_907_4 990285.RGCCGE502_00705 1.59e-47 162.0 COG2808@1|root,COG2808@2|Bacteria,1N1B9@1224|Proteobacteria,2U5JV@28211|Alphaproteobacteria,4B92H@82115|Rhizobiaceae 28211|Alphaproteobacteria K Transcriptional regulator - - - ko:K07734 - - - - ko00000,ko03000 - - - FMN_bind_2 k141_24619_1 223926.28807745 4.57e-135 393.0 COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,1RPM2@1236|Gammaproteobacteria,1XTT6@135623|Vibrionales 135623|Vibrionales L it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k141_24619_2 1219076.N646_1830 1.1e-148 421.0 COG3137@1|root,COG3137@2|Bacteria,1N9KB@1224|Proteobacteria,1THEB@1236|Gammaproteobacteria,1XUUB@135623|Vibrionales 135623|Vibrionales M salt-induced outer membrane protein VP2736 - - ko:K07283 - - - - ko00000 - - - DUF481 k141_24619_3 223926.28807747 2.33e-91 268.0 COG0359@1|root,COG0359@2|Bacteria,1RD0R@1224|Proteobacteria,1S3WS@1236|Gammaproteobacteria,1XU9I@135623|Vibrionales 135623|Vibrionales J Binds to the 23S rRNA rplI GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02939 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L9_C,Ribosomal_L9_N k141_24619_5 1219077.VAZ01S_057_00180 9.48e-65 197.0 COG2965@1|root,COG2965@2|Bacteria,1RHIE@1224|Proteobacteria,1S6H5@1236|Gammaproteobacteria,1XXV4@135623|Vibrionales 135623|Vibrionales L Binds single-stranded DNA at the primosome assembly site (PAS) priB GO:0000228,GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005657,GO:0005658,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0018130,GO:0019438,GO:0030880,GO:0030894,GO:0031974,GO:0031981,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043596,GO:0043601,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044454,GO:0044464,GO:0046483,GO:0055029,GO:0061695,GO:0070013,GO:0071704,GO:0090304,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 - ko:K02686 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - SSB k141_24619_6 1219076.N646_1834 5.88e-84 248.0 COG0360@1|root,COG0360@2|Bacteria,1RH82@1224|Proteobacteria,1S5VU@1236|Gammaproteobacteria,1XWUY@135623|Vibrionales 135623|Vibrionales J Binds together with S18 to 16S ribosomal RNA rpsF GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02990 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S6 k141_24619_7 1191299.AJYX01000051_gene1223 8.59e-148 417.0 COG0036@1|root,COG0036@2|Bacteria,1MUZM@1224|Proteobacteria,1RN3K@1236|Gammaproteobacteria,1XU07@135623|Vibrionales 135623|Vibrionales G Belongs to the ribulose-phosphate 3-epimerase family rpe - 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 - - - Ribul_P_3_epim k141_24619_8 1116375.VEJY3_14030 1.57e-198 550.0 COG0338@1|root,COG0338@2|Bacteria,1P85S@1224|Proteobacteria,1RMNW@1236|Gammaproteobacteria,1XV7I@135623|Vibrionales 135623|Vibrionales H Site-specific DNA-methyltransferase (adenine-specific) dam - 2.1.1.72 ko:K06223 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 - - - MethyltransfD12 k141_24619_9 1116375.VEJY3_14035 7.22e-237 665.0 COG3266@1|root,COG3267@1|root,COG3266@2|Bacteria,COG3267@2|Bacteria,1Q1YI@1224|Proteobacteria,1S965@1236|Gammaproteobacteria,1XSV9@135623|Vibrionales 135623|Vibrionales U AAA domain VP2743 - - ko:K03112 - - - - ko00000 - - - AAA_22,SPOR k141_24619_10 1219076.N646_1838 5.17e-250 687.0 COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,1RN4I@1236|Gammaproteobacteria,1XU0D@135623|Vibrionales 135623|Vibrionales E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) aroB GO:0003674,GO:0003824,GO:0003856,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 4.2.3.4 ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03083 RC00847 ko00000,ko00001,ko00002,ko01000 - - - DHQ_synthase k141_24619_11 1219076.N646_1839 3.3e-113 325.0 COG0703@1|root,COG0703@2|Bacteria,1MUFJ@1224|Proteobacteria,1RPF6@1236|Gammaproteobacteria,1XTR6@135623|Vibrionales 135623|Vibrionales F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate aroK GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - SKI k141_24619_12 223926.28807756 0.0 1004.0 COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,1RN3Z@1236|Gammaproteobacteria,1XSBC@135623|Vibrionales 135623|Vibrionales U COG4796 Type II secretory pathway, component HofQ pilQ - - ko:K02666 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - STN,Secretin,Secretin_N k141_24619_13 223926.28807757 9.44e-108 311.0 COG3168@1|root,COG3168@2|Bacteria,1RI6V@1224|Proteobacteria,1S6VJ@1236|Gammaproteobacteria,1XVB7@135623|Vibrionales 135623|Vibrionales NU assembly protein PilP pilP - - ko:K02665 - - - - ko00000,ko02035,ko02044 - - - PilP k141_24619_14 223926.28807758 3.42e-125 358.0 COG3167@1|root,COG3167@2|Bacteria,1RBGW@1224|Proteobacteria,1S3XQ@1236|Gammaproteobacteria,1XVAF@135623|Vibrionales 135623|Vibrionales NU assembly protein PilO pilO - - ko:K02664 - - - - ko00000,ko02035,ko02044 - - - PilO k141_24619_15 1116375.VEJY3_14065 2.23e-118 340.0 COG3166@1|root,COG3166@2|Bacteria,1RF1S@1224|Proteobacteria,1S3S0@1236|Gammaproteobacteria,1XX7X@135623|Vibrionales 135623|Vibrionales NU assembly protein PilN pilN - - ko:K02663 - - - - ko00000,ko02035,ko02044 - - - PilN k141_24619_16 223926.28807760 2.98e-60 194.0 COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,1RN8S@1236|Gammaproteobacteria,1XTH1@135623|Vibrionales 135623|Vibrionales NU COG4972 Tfp pilus assembly protein, ATPase PilM pilM - - ko:K02662 - - - - ko00000,ko02035,ko02044 - - - PilM_2 k141_12860_2 1396858.Q666_15150 1.28e-99 303.0 COG3547@1|root,COG3547@2|Bacteria,1MXKJ@1224|Proteobacteria,1RSCP@1236|Gammaproteobacteria,465IU@72275|Alteromonadaceae 1236|Gammaproteobacteria L Transposase IS116/IS110/IS902 family Z012_08285 - - ko:K07486 - - - - ko00000 - - - DEDD_Tnp_IS110,Transposase_20 k141_4324_1 1294265.JCM21738_3760 1.01e-138 398.0 COG0489@1|root,COG0489@2|Bacteria,1TQ34@1239|Firmicutes,4HAW4@91061|Bacilli,1ZC2E@1386|Bacillus 91061|Bacilli D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP mrp GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K03593 - - - - ko00000,ko03029,ko03036 - - - FeS_assembly_P,ParA k141_6822_1 1211114.ALIP01000129_gene1369 6.42e-47 155.0 COG3791@1|root,COG3791@2|Bacteria,1N023@1224|Proteobacteria,1SAQH@1236|Gammaproteobacteria,1X79M@135614|Xanthomonadales 135614|Xanthomonadales S Glutathione-dependent formaldehyde-activating enzyme - - - - - - - - - - - - GFA k141_18840_1 218284.CCDN010000004_gene3095 1.43e-52 166.0 2E2U4@1|root,32XW8@2|Bacteria,1VAT9@1239|Firmicutes,4HN53@91061|Bacilli,1ZHZK@1386|Bacillus 91061|Bacilli S YhdB-like protein yhdB - - - - - - - - - - - YhdB k141_3110_1 1196031.ALEG01000045_gene4480 3.63e-96 285.0 COG1811@1|root,COG1811@2|Bacteria,1UH19@1239|Firmicutes,4HB4E@91061|Bacilli,1ZBSK@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF554) ydfK - - ko:K07150 - - - - ko00000 - - - DUF554 k141_35365_1 1042377.AFPJ01000036_gene1150 9.96e-95 290.0 COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,1RPAB@1236|Gammaproteobacteria,469E2@72275|Alteromonadaceae 1236|Gammaproteobacteria C Glycolate oxidase iron-sulfur subunit glcF - - ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001 - - - CCG,Fer4_7,Fer4_8 k141_18841_1 1385514.N782_20705 5.26e-25 98.2 2CESQ@1|root,34AAA@2|Bacteria,1VYVE@1239|Firmicutes,4HY3F@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - k141_18841_3 1382305.AZUC01000049_gene1599 3.57e-12 66.6 COG1708@1|root,COG1708@2|Bacteria,1VXEG@1239|Firmicutes,4HXJA@91061|Bacilli 91061|Bacilli S Streptomycin adenylyltransferase - - - - - - - - - - - - Adenyl_transf k141_4325_1 945550.VISI1226_10552 5.5e-38 132.0 COG1284@1|root,COG1284@2|Bacteria,1RDIV@1224|Proteobacteria,1RSIN@1236|Gammaproteobacteria,1XT16@135623|Vibrionales 135623|Vibrionales S Uncharacterised 5xTM membrane BCR, YitT family COG1284 - - - - - - - - - - - - YitT_membrane k141_34102_1 269799.Gmet_1666 1.01e-05 47.8 COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,42MRU@68525|delta/epsilon subdivisions,2WIQX@28221|Deltaproteobacteria 28221|Deltaproteobacteria MU TIGRFAM RND efflux system, outer membrane lipoprotein, NodT - - - - - - - - - - - - OEP k141_34102_2 1044.EH31_10355 2.26e-22 93.6 COG1226@1|root,32YV7@2|Bacteria,1N7MV@1224|Proteobacteria,2U76Q@28211|Alphaproteobacteria,2K5GP@204457|Sphingomonadales 204457|Sphingomonadales P Ion channel - - - - - - - - - - - - Ion_trans_2 k141_34102_3 28258.KP05_13905 2.81e-12 67.8 COG1292@1|root,COG1292@2|Bacteria,1MV0K@1224|Proteobacteria,1RP3E@1236|Gammaproteobacteria,1XNN7@135619|Oceanospirillales 135619|Oceanospirillales U Belongs to the BCCT transporter (TC 2.A.15) family - - - ko:K03451 - - - - ko00000 2.A.15 - - BCCT k141_34102_4 1042377.AFPJ01000042_gene1015 2.24e-149 442.0 COG1472@1|root,COG1472@2|Bacteria,1MVAJ@1224|Proteobacteria,1RMQF@1236|Gammaproteobacteria,465G4@72275|Alteromonadaceae 1236|Gammaproteobacteria G Beta-N-acetylhexosaminidase ybbD - 3.2.1.52 ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 M00628 R00022,R05963,R07809,R07810,R10831 RC00049 ko00000,ko00001,ko00002,ko01000 - - - Glyco_hydro_3,Glyco_hydro_3_C k141_3111_1 1033734.CAET01000074_gene2837 7.54e-18 77.8 2ESGB@1|root,33K11@2|Bacteria,1VMXB@1239|Firmicutes,4HSPU@91061|Bacilli,1ZKDF@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_23590_1 1122925.KB895381_gene3814 1.28e-70 231.0 COG2755@1|root,COG2755@2|Bacteria,1UIB3@1239|Firmicutes,4HMW0@91061|Bacilli,277FZ@186822|Paenibacillaceae 91061|Bacilli E Pfam:DUF303 - - 3.1.1.53 ko:K05970 - - - - ko00000,ko01000 - - - SASA k141_23590_2 1116375.VEJY3_02915 8.65e-117 348.0 COG1070@1|root,COG1070@2|Bacteria,1N51F@1224|Proteobacteria,1RQX6@1236|Gammaproteobacteria,1XWBF@135623|Vibrionales 135623|Vibrionales H FGGY family of carbohydrate kinases, N-terminal domain - - 2.7.1.5 ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 - R01902,R03014 RC00002,RC00017 ko00000,ko00001,ko01000 - - - FGGY_C,FGGY_N k141_32795_1 218284.CCDN010000001_gene1400 8.94e-161 457.0 COG0003@1|root,COG0003@2|Bacteria,1TQZP@1239|Firmicutes,4HBKG@91061|Bacilli,1ZBGF@1386|Bacillus 91061|Bacilli D Anion-transporting ATPase arsA - 3.6.3.16 ko:K01551 - - - - ko00000,ko01000,ko02000 3.A.19.1,3.A.21.1,3.A.4.1 - - ArsA_ATPase k141_11638_1 223926.28809062 1.99e-166 474.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1XW7E@135623|Vibrionales 135623|Vibrionales T Bacterial regulatory protein, Fis family - - - ko:K08476 ko02020,map02020 M00503 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activ_2 k141_11638_2 1116375.VEJY3_20106 0.0 1984.0 COG3325@1|root,COG3866@1|root,COG3979@1|root,COG3325@2|Bacteria,COG3866@2|Bacteria,COG3979@2|Bacteria,1R3YZ@1224|Proteobacteria,1RY6I@1236|Gammaproteobacteria,1XTSH@135623|Vibrionales 135623|Vibrionales G protein contain chitin-binding domain type 3 - - 3.2.1.14,3.2.1.202 ko:K01183,ko:K21606 ko00520,ko01100,map00520,map01100 - R01206,R02334 RC00467 ko00000,ko00001,ko01000 - CBM5,GH18 - CBM_5_12_2,ChiC,Glyco_hydro_18 k141_18842_1 218284.CCDN010000006_gene3510 5.72e-57 177.0 COG0640@1|root,COG0640@2|Bacteria,1VFY4@1239|Firmicutes,4HP5T@91061|Bacilli,1ZQGJ@1386|Bacillus 91061|Bacilli K helix_turn_helix, Arsenical Resistance Operon Repressor - - - - - - - - - - - - HTH_5 k141_6825_1 1408424.JHYI01000021_gene68 3.41e-11 60.1 COG0346@1|root,COG0346@2|Bacteria,1V42J@1239|Firmicutes,4HHHX@91061|Bacilli,1ZHNW@1386|Bacillus 91061|Bacilli E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - Glyoxalase k141_6825_2 406124.ACPC01000009_gene1484 9.7e-65 206.0 COG1595@1|root,COG1595@2|Bacteria,1V8BF@1239|Firmicutes,4HJ64@91061|Bacilli,1ZEJV@1386|Bacillus 91061|Bacilli K Sigma-70, region 4 - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_35366_1 1385514.N782_21895 2.5e-27 112.0 COG2909@1|root,COG3629@1|root,COG2909@2|Bacteria,COG3629@2|Bacteria,1UWHI@1239|Firmicutes,4HADH@91061|Bacilli,2YBFE@289201|Pontibacillus 91061|Bacilli K Bacterial transcriptional activator domain - - - ko:K03556 - - - - ko00000,ko03000 - - - AAA_16,BTAD,TPR_12,TPR_8 k141_25910_1 1116375.VEJY3_22456 0.0 1053.0 COG1018@1|root,COG3217@1|root,COG1018@2|Bacteria,COG3217@2|Bacteria,1MXN2@1224|Proteobacteria,1RMN7@1236|Gammaproteobacteria,1XSP5@135623|Vibrionales 135623|Vibrionales C Fe-S protein VVA0408 - - ko:K07140 - - - - ko00000 - - - FAD_binding_6,Fer2,MOSC,MOSC_N,NAD_binding_1 k141_25910_2 1116375.VEJY3_22451 1.88e-184 514.0 COG0171@1|root,COG0171@2|Bacteria,1MU9U@1224|Proteobacteria,1RNKA@1236|Gammaproteobacteria,1XSFI@135623|Vibrionales 135623|Vibrionales F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source nadE - 6.3.1.5 ko:K01916 ko00760,ko01100,map00760,map01100 M00115 R00189 RC00100 ko00000,ko00001,ko00002,ko01000 - - - NAD_synthase k141_25910_3 223926.28808579 1.61e-111 322.0 COG1057@1|root,COG1057@2|Bacteria,1N1IS@1224|Proteobacteria,1SA2H@1236|Gammaproteobacteria,1XWZ4@135623|Vibrionales 135623|Vibrionales H adenylyltransferase nadD - 2.7.7.18 ko:K00969 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like k141_25910_4 1116375.VEJY3_22441 2.96e-92 271.0 29KEN@1|root,307BY@2|Bacteria,1QJQ0@1224|Proteobacteria,1THR1@1236|Gammaproteobacteria,1XX8P@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_25910_5 1116375.VEJY3_22436 6.8e-123 352.0 28R69@1|root,2ZDKA@2|Bacteria,1P5DZ@1224|Proteobacteria,1SW5A@1236|Gammaproteobacteria,1XWIU@135623|Vibrionales 135623|Vibrionales S COG2207 AraC-type DNA-binding domain-containing proteins VPA0415 - - - - - - - - - - - AraC_binding k141_25910_6 1116375.VEJY3_22431 1.97e-255 701.0 COG0204@1|root,COG0204@2|Bacteria,1MUFH@1224|Proteobacteria,1RNJQ@1236|Gammaproteobacteria,1XSQX@135623|Vibrionales 135623|Vibrionales I Phosphate acyltransferases - - - - - - - - - - - - Acyltransferase k141_14165_2 1051646.VITU9109_25885 2.48e-06 46.6 COG0335@1|root,COG0335@2|Bacteria,1RH3A@1224|Proteobacteria,1S5XX@1236|Gammaproteobacteria,1XXCD@135623|Vibrionales 135623|Vibrionales J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site rplS GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02884 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L19 k141_6826_2 218284.CCDN010000006_gene3633 2.11e-54 171.0 COG0789@1|root,COG0789@2|Bacteria,1VABB@1239|Firmicutes,4HMSS@91061|Bacilli,1ZHYS@1386|Bacillus 91061|Bacilli K transcriptional tnrA GO:0001047,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0006808,GO:0007154,GO:0007584,GO:0008150,GO:0009605,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0042221,GO:0043562,GO:0044212,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070887,GO:0071310,GO:0071417,GO:0071495,GO:0071496,GO:0071944,GO:0080090,GO:0090293,GO:0090294,GO:0097159,GO:1901363,GO:1901698,GO:1901699,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - - - - - - - - - - MerR_1 k141_15008_1 218284.CCDN010000006_gene3530 1.49e-60 196.0 2DH6Y@1|root,2ZYKQ@2|Bacteria,1V3RR@1239|Firmicutes,4HHKE@91061|Bacilli,1ZBHI@1386|Bacillus 91061|Bacilli S Spore germination B3/ GerAC like, C-terminal - - - ko:K06308 - - - - ko00000 - - - Spore_GerAC k141_20916_1 1294265.JCM21738_2873 2.64e-133 393.0 COG1283@1|root,COG1283@2|Bacteria,1TP4K@1239|Firmicutes,4HAZ0@91061|Bacilli,1ZBHZ@1386|Bacillus 91061|Bacilli P COG1283 Na phosphate symporter yjbB - - ko:K03324 - - - - ko00000,ko02000 2.A.58.2 - - Na_Pi_cotrans,PhoU k141_35367_1 1123073.KB899241_gene3412 9.11e-10 61.6 2AKEY@1|root,31B6D@2|Bacteria,1Q7UW@1224|Proteobacteria,1T82M@1236|Gammaproteobacteria,1X7TB@135614|Xanthomonadales 135614|Xanthomonadales S Protein of unknown function (DUF3011) - - - - - - - - - - - - DUF3011 k141_4326_2 218284.CCDN010000004_gene3029 4.85e-99 295.0 COG2208@1|root,COG2208@2|Bacteria,1TQY5@1239|Firmicutes,4HAF6@91061|Bacilli,1ZBIB@1386|Bacillus 91061|Bacilli KT phosphatase rsbU - 3.1.3.3 ko:K07315 - - - - ko00000,ko01000,ko03021 - - - RsbU_N,SpoIIE k141_18844_1 1453501.JELR01000001_gene3122 6.47e-29 109.0 COG1489@1|root,COG1489@2|Bacteria,1MUC3@1224|Proteobacteria,1RQ95@1236|Gammaproteobacteria,466BU@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the SfsA family sfsA GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005975,GO:0006355,GO:0008150,GO:0008152,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0044238,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - ko:K06206 - - - - ko00000 - - - SfsA k141_18844_2 1453501.JELR01000001_gene3121 3.57e-77 230.0 COG2146@1|root,COG2146@2|Bacteria,1N72F@1224|Proteobacteria,1SD0G@1236|Gammaproteobacteria,468PW@72275|Alteromonadaceae 1236|Gammaproteobacteria P Rieske [2Fe-2S] domain - - - - - - - - - - - - Rieske k141_5700_1 42565.FP66_00170 2.11e-90 267.0 COG0625@1|root,COG0625@2|Bacteria,1MXJD@1224|Proteobacteria,1RP12@1236|Gammaproteobacteria,1XI89@135619|Oceanospirillales 135619|Oceanospirillales O Stringent starvation protein A sspA - - ko:K03599 - - - - ko00000,ko02000,ko03021 1.A.12.3.1 - - GST_C,GST_N,GST_N_3 k141_5700_2 42565.FP66_00175 3.36e-47 154.0 COG2969@1|root,COG2969@2|Bacteria,1MZ2Q@1224|Proteobacteria,1S8WT@1236|Gammaproteobacteria,1XKFH@135619|Oceanospirillales 135619|Oceanospirillales S Stringent starvation protein B sspB - - ko:K03600 - - - - ko00000,ko03021 - - - SspB k141_5706_2 1116375.VEJY3_13805 7.07e-44 148.0 2DSY5@1|root,33HWU@2|Bacteria,1N9DQ@1224|Proteobacteria,1T39J@1236|Gammaproteobacteria,1Y34K@135623|Vibrionales 135623|Vibrionales - - - - - ko:K12286 - - - - ko00000,ko02044 - - - - k141_5706_3 674977.VMC_34960 7.42e-73 228.0 COG4966@1|root,COG4966@2|Bacteria,1QUGF@1224|Proteobacteria,1T1Y7@1236|Gammaproteobacteria,1Y32P@135623|Vibrionales 135623|Vibrionales NU Prokaryotic N-terminal methylation motif - - - ko:K12285 - - - - ko00000,ko02044 - - - N_methyl k141_5706_4 1116375.VEJY3_13815 3.55e-12 64.7 COG2165@1|root,COG2165@2|Bacteria,1QUGH@1224|Proteobacteria,1T1Y8@1236|Gammaproteobacteria,1XXTW@135623|Vibrionales 135623|Vibrionales NU COG2165 Type II secretory pathway, pseudopilin PulG mshD - - ko:K10927 ko05111,map05111 - - - ko00000,ko00001,ko02044 - - - N_methyl k141_18863_1 1121923.GPUN_2351 9.56e-77 249.0 COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,1RMZ8@1236|Gammaproteobacteria,465MP@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1024 Enoyl-CoA hydratase carnithine racemase fadJ - 1.1.1.35,4.2.1.17,5.1.2.3 ko:K01782 ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212 M00032,M00087 R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094 RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 - - - 3HCDH,3HCDH_N,ECH_1 k141_22261_1 1116375.VEJY3_03245 1.94e-178 498.0 COG1464@1|root,COG1464@2|Bacteria,1MUVY@1224|Proteobacteria,1RS3R@1236|Gammaproteobacteria,1XU8C@135623|Vibrionales 135623|Vibrionales M Belongs to the nlpA lipoprotein family metQ - - ko:K02073 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - Lipoprotein_9 k141_23605_2 171693.BN988_02846 2.84e-24 104.0 COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,4H9SP@91061|Bacilli,23IKS@182709|Oceanobacillus 91061|Bacilli P Heavy-metal-associated domain cadA - 3.6.3.3,3.6.3.5 ko:K01534 - - - - ko00000,ko01000 3.A.3.6 - - E1-E2_ATPase,HMA,Hydrolase k141_36307_1 665959.HMPREF1013_03582 3.6e-93 287.0 COG4819@1|root,COG4819@2|Bacteria,1TQ6T@1239|Firmicutes,4HAEM@91061|Bacilli,1ZDKX@1386|Bacillus 91061|Bacilli E Ethanolamine utilisation protein EutA eutA - - ko:K04019 ko00564,ko01100,map00564,map01100 - R00749 RC00370 ko00000,ko00001 - - - EutA k141_15021_1 218284.CCDN010000002_gene2948 2.3e-115 334.0 COG3694@1|root,COG3694@2|Bacteria,1TR4N@1239|Firmicutes,4HDII@91061|Bacilli,1ZAWY@1386|Bacillus 91061|Bacilli S transport system, permease component M1-957 - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_6 k141_15021_2 218284.CCDN010000002_gene2949 1.35e-18 80.1 COG1226@1|root,32UM6@2|Bacteria,1VC22@1239|Firmicutes,4HMGA@91061|Bacilli,1ZJ2P@1386|Bacillus 91061|Bacilli P Ion transport - - - ko:K08713 - - - - ko00000,ko02000 1.A.1.29.1 - - Ion_trans_2 k141_27274_1 1116375.VEJY3_23516 0.0 892.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XSRH@135623|Vibrionales 135623|Vibrionales T signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - 3.1.4.52 ko:K20962 ko05111,map05111 - - - ko00000,ko00001,ko01000 - - - EAL,GGDEF,Response_reg k141_27274_2 945550.VISI1226_10812 3.03e-276 756.0 COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,1RNS6@1236|Gammaproteobacteria,1XSBG@135623|Vibrionales 135623|Vibrionales H Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA kbl - 2.3.1.29 ko:K00639 ko00260,map00260 - R00371 RC00004,RC00394 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 k141_27274_3 1280001.BAOA01000050_gene1349 2.72e-247 679.0 COG1063@1|root,COG1063@2|Bacteria,1MV9A@1224|Proteobacteria,1RMNY@1236|Gammaproteobacteria,1XUZV@135623|Vibrionales 135623|Vibrionales C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate tdh - 1.1.1.103 ko:K00060 ko00260,map00260 - R01465 RC00525 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N k141_27274_4 754436.JCM19237_1736 3.6e-283 792.0 COG1061@1|root,COG2932@1|root,COG1061@2|Bacteria,COG2932@2|Bacteria,1MV9F@1224|Proteobacteria,1RNAN@1236|Gammaproteobacteria,1XUZY@135623|Vibrionales 135623|Vibrionales L helicase superfamily c-terminal domain - - - - - - - - - - - - DUF3427,Helicase_C,PLDc_2,ResIII k141_24635_2 218284.CCDN010000012_gene4432 4.28e-54 172.0 COG0386@1|root,COG0386@2|Bacteria,1V3M3@1239|Firmicutes,4HH5Q@91061|Bacilli,1ZGBN@1386|Bacillus 91061|Bacilli O Belongs to the glutathione peroxidase family bsaA - 1.11.1.9 ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 - R00274,R07034,R07035 RC00011,RC00982 ko00000,ko00001,ko01000 - - - GSHPx k141_4337_1 223926.28809249 7.53e-35 119.0 COG0607@1|root,32YCZ@2|Bacteria,1N6NN@1224|Proteobacteria,1SCRA@1236|Gammaproteobacteria,1XYYX@135623|Vibrionales 135623|Vibrionales P Protein of unknown function (DUF2892) - - - - - - - - - - - - DUF2892 k141_4337_2 1116375.VEJY3_19656 1.43e-279 772.0 COG0446@1|root,COG0607@1|root,COG0446@2|Bacteria,COG0607@2|Bacteria,1NR3M@1224|Proteobacteria,1T1WT@1236|Gammaproteobacteria,1XSS8@135623|Vibrionales 135623|Vibrionales P NAD(FAD)-dependent dehydrogenases cdr - - - - - - - - - - - Pyr_redox_2,Pyr_redox_dim,Rhodanese k141_15022_1 42565.FP66_10535 1.98e-120 353.0 COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,1RNEW@1236|Gammaproteobacteria,1XH80@135619|Oceanospirillales 135619|Oceanospirillales F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP purA - 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 - - - Adenylsucc_synt k141_18865_1 1243664.CAVL020000006_gene4839 4.5e-27 100.0 2DNS1@1|root,32YVX@2|Bacteria,1VEGC@1239|Firmicutes,4HPC6@91061|Bacilli,1ZJ6M@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2905) yrzS - - - - - - - - - - - DUF2905 k141_3124_1 1120971.AUCA01000034_gene3115 2.92e-50 166.0 COG0454@1|root,COG0454@2|Bacteria,1V4EA@1239|Firmicutes,4HHBF@91061|Bacilli 91061|Bacilli K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases ysnE GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031248,GO:0031365,GO:0032991,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564,GO:1902493,GO:1902494,GO:1990234 - ko:K03829 - - - - ko00000,ko01000 - - - Acetyltransf_1 k141_25923_1 1279017.AQYJ01000022_gene2702 4.8e-102 304.0 COG0589@1|root,COG0589@2|Bacteria,1PAFP@1224|Proteobacteria,1RSCS@1236|Gammaproteobacteria,465CE@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - - - - - - - - - - Usp k141_25923_2 1122604.JONR01000020_gene445 3.25e-75 235.0 COG3000@1|root,COG3000@2|Bacteria,1R4RM@1224|Proteobacteria,1SAME@1236|Gammaproteobacteria,1XA9M@135614|Xanthomonadales 135614|Xanthomonadales I sterol desaturase - - - - - - - - - - - - FA_hydroxylase k141_25923_3 1453501.JELR01000001_gene3142 8.04e-75 226.0 COG1607@1|root,COG1607@2|Bacteria,1N13R@1224|Proteobacteria,1S956@1236|Gammaproteobacteria,466SK@72275|Alteromonadaceae 1236|Gammaproteobacteria I thioesterase - - - - - - - - - - - - 4HBT k141_5707_1 218284.CCDN010000001_gene656 1.37e-112 335.0 COG1055@1|root,COG1055@2|Bacteria,1TPNN@1239|Firmicutes,4HAIC@91061|Bacilli,1ZBBN@1386|Bacillus 91061|Bacilli P Membrane arsB_2 - - ko:K03893 - - - - ko00000,ko02000 2.A.45.1,3.A.4.1 - - CitMHS k141_11855_2 218284.CCDN010000002_gene2879 4.85e-56 191.0 COG1001@1|root,COG1001@2|Bacteria,1TP84@1239|Firmicutes,4HBB2@91061|Bacilli,1ZCHI@1386|Bacillus 91061|Bacilli F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family ade GO:0003674,GO:0003824,GO:0006040,GO:0006044,GO:0006046,GO:0008150,GO:0008152,GO:0008448,GO:0009056,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0046348,GO:0071704,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901575 3.5.4.2 ko:K01486 ko00230,ko01100,map00230,map01100 - R01244 RC00477 ko00000,ko00001,ko01000 - - iYO844.BSU14520 Adenine_deam_C,Amidohydro_1 k141_22525_1 218284.CCDN010000002_gene2325 5.11e-36 127.0 COG0702@1|root,COG0702@2|Bacteria,1TQFS@1239|Firmicutes,4HDA2@91061|Bacilli,1ZBH3@1386|Bacillus 91061|Bacilli GM NmrA-like family yhfK GO:0005575,GO:0005622,GO:0005623,GO:0044464 - - - - - - - - - - NAD_binding_10 k141_3291_1 218284.CCDN010000002_gene1984 4.86e-148 426.0 COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,4HACW@91061|Bacilli,1ZC7P@1386|Bacillus 91061|Bacilli F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily purB GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS09895 ADSL_C,Lyase_1 k141_10507_2 1116375.VEJY3_19731 0.0 869.0 COG1492@1|root,COG1492@2|Bacteria,1MUFY@1224|Proteobacteria,1RP8G@1236|Gammaproteobacteria,1XV2B@135623|Vibrionales 135623|Vibrionales H Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation cobQ GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.5.10 ko:K02232 ko00860,ko01100,map00860,map01100 M00122 R05225 RC00010,RC01302 ko00000,ko00001,ko00002,ko01000 - - - AAA_26,CbiA,GATase_3 k141_10507_3 1219076.N646_4320 2.08e-103 301.0 2B0QJ@1|root,31MNT@2|Bacteria,1QJGF@1224|Proteobacteria,1THG6@1236|Gammaproteobacteria,1XVJQ@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_10507_4 1116375.VEJY3_19721 5.19e-110 322.0 COG4067@1|root,COG4067@2|Bacteria,1N7Y2@1224|Proteobacteria,1SBQN@1236|Gammaproteobacteria,1XUTD@135623|Vibrionales 135623|Vibrionales O protein conserved in archaea - - - - - - - - - - - - Zn_protease k141_10507_5 1116375.VEJY3_19711 1.79e-184 515.0 COG2207@1|root,COG2207@2|Bacteria,1NA3B@1224|Proteobacteria,1SYN5@1236|Gammaproteobacteria,1Y2TG@135623|Vibrionales 135623|Vibrionales K AraC-like ligand binding domain - - - - - - - - - - - - AraC_binding,HTH_18 k141_10507_6 1116375.VEJY3_19706 7.85e-270 746.0 COG0534@1|root,COG0534@2|Bacteria,1QTIW@1224|Proteobacteria,1RPEX@1236|Gammaproteobacteria,1Y2KN@135623|Vibrionales 135623|Vibrionales V Na driven multidrug efflux pump - - - - - - - - - - - - MatE k141_10507_7 223926.28809241 2.05e-110 317.0 COG0602@1|root,COG0602@2|Bacteria,1RA7S@1224|Proteobacteria,1S20X@1236|Gammaproteobacteria,1XWZH@135623|Vibrionales 135623|Vibrionales O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine nrdG GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008998,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046385,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901576 1.97.1.4 ko:K04068 - - R04710 - ko00000,ko01000 - - - Fer4_12 k141_10507_8 1219076.N646_4327 4.37e-206 586.0 COG1328@1|root,COG1328@2|Bacteria,1MWMS@1224|Proteobacteria,1RNHS@1236|Gammaproteobacteria,1XU99@135623|Vibrionales 135623|Vibrionales F Ribonucleoside-triphosphate reductase nrdD - 1.1.98.6 ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R11633,R11634,R11635,R11636 RC00613 ko00000,ko00001,ko00002,ko01000 - - - ATP-cone,NRDD k141_35576_1 1056820.KB900674_gene2484 3.19e-22 99.4 COG3675@1|root,COG3675@2|Bacteria,1PI8G@1224|Proteobacteria,1RP6A@1236|Gammaproteobacteria,2PQ2S@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria I Lipase (class 3) - - - - - - - - - - - - Lipase_3 k141_34276_2 1116375.VEJY3_06095 9.71e-79 235.0 2AWAE@1|root,31N5Y@2|Bacteria,1QJXB@1224|Proteobacteria,1THZD@1236|Gammaproteobacteria,1XXZU@135623|Vibrionales 135623|Vibrionales D Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division - - - ko:K13053 - - - - ko00000,ko03036 - - - SulA k141_34276_3 1116375.VEJY3_06100 3.01e-39 130.0 2AWQN@1|root,31NMK@2|Bacteria,1QKC8@1224|Proteobacteria,1TIFR@1236|Gammaproteobacteria,1XZ1R@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_34276_4 223926.28806254 5.74e-122 360.0 COG0790@1|root,COG2214@1|root,COG0790@2|Bacteria,COG2214@2|Bacteria,1RK20@1224|Proteobacteria,1SWG0@1236|Gammaproteobacteria,1Y33Q@135623|Vibrionales 135623|Vibrionales O COG0790 FOG TPR repeat, SEL1 subfamily - - - ko:K07126 - - - - ko00000 - - - Sel1 k141_34276_5 223926.28806255 1.32e-116 338.0 COG2885@1|root,COG2885@2|Bacteria,1MYBP@1224|Proteobacteria,1RVRF@1236|Gammaproteobacteria,1XW50@135623|Vibrionales 135623|Vibrionales M Belongs to the ompA family yiaD - - - - - - - - - - - Gly-zipper_Omp,OmpA k141_34276_6 223926.28806256 4.77e-151 426.0 2CPPK@1|root,32SJJ@2|Bacteria,1MZQ2@1224|Proteobacteria,1SABH@1236|Gammaproteobacteria,1XU68@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF2786) VV12383 - - - - - - - - - - - DUF2786 k141_34276_7 223926.28806257 2.16e-142 404.0 COG1776@1|root,COG1776@2|Bacteria,1N5S9@1224|Proteobacteria,1RMT0@1236|Gammaproteobacteria,1XVBM@135623|Vibrionales 135623|Vibrionales NT Protein of unknown function (DUF3334) SO2241 - - - - - - - - - - - DUF3334 k141_34276_8 1116375.VEJY3_06125 0.0 1323.0 COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,1RQX2@1236|Gammaproteobacteria,1XU87@135623|Vibrionales 135623|Vibrionales C COG0277 FAD FMN-containing dehydrogenases ydiJ - - - - - - - - - - - FAD-oxidase_C,FAD_binding_4,Fer4_8 k141_33006_1 345219.Bcoa_0122 1.15e-124 370.0 COG3573@1|root,COG3573@2|Bacteria,1UY39@1239|Firmicutes,4HBS3@91061|Bacilli,1ZDXA@1386|Bacillus 91061|Bacilli S FAD binding domain - - - ko:K07077 - - - - ko00000 - - - FAD_binding_2 k141_29502_1 218284.CCDN010000006_gene3506 1.28e-66 204.0 COG1658@1|root,COG1658@2|Bacteria,1VBXW@1239|Firmicutes,4HKN4@91061|Bacilli,1ZH1R@1386|Bacillus 91061|Bacilli L COG1658 Small primase-like proteins (Toprim domain) yusF GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043822,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 - ko:K07476 - - - - ko00000 - - - Toprim,Toprim_2 k141_15151_1 223926.28809535 2.77e-204 568.0 COG1275@1|root,COG1275@2|Bacteria,1QMVH@1224|Proteobacteria,1RS7F@1236|Gammaproteobacteria,1XTYA@135623|Vibrionales 135623|Vibrionales P COG1275 Tellurite resistance protein and related permeases - - - - - - - - - - - - SLAC1 k141_17499_1 218284.CCDN010000002_gene2048 2.59e-56 176.0 COG0526@1|root,COG0526@2|Bacteria,1VFUD@1239|Firmicutes,4HNQS@91061|Bacilli,1ZJBR@1386|Bacillus 91061|Bacilli CO Thioredoxin ydfQ - - - - - - - - - - - Thioredoxin k141_30436_1 218284.CCDN010000006_gene3598 1.45e-25 96.3 2DNDI@1|root,32WZ0@2|Bacteria,1VG75@1239|Firmicutes,4HQ78@91061|Bacilli 91061|Bacilli S Glutaredoxin - - - - - - - - - - - - Glutaredoxin k141_1128_6 420246.GTNG_2842 5.48e-46 153.0 2F7DN@1|root,33ZUM@2|Bacteria,1VXKR@1239|Firmicutes,4HXTF@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - k141_1128_9 1234664.AMRO01000024_gene1796 9.84e-25 97.4 2DM82@1|root,324KK@2|Bacteria,1V9IJ@1239|Firmicutes,4HJEV@91061|Bacilli,1WGSK@129337|Geobacillus 91061|Bacilli - - - - 3.1.22.4 ko:K01159 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - - k141_11856_1 218284.CCDN010000002_gene2759 2.31e-123 357.0 COG0266@1|root,COG0266@2|Bacteria,1TP6F@1239|Firmicutes,4HBIU@91061|Bacilli,1ZCVD@1386|Bacillus 91061|Bacilli L Formamidopyrimidine-DNA glycosylase H2TH domain - - 4.2.99.18 ko:K05522 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Fapy_DNA_glyco,H2TH,zf-FPG_IleRS k141_35577_1 1340434.AXVA01000008_gene3644 1.47e-77 238.0 COG1802@1|root,COG1802@2|Bacteria,1TSV2@1239|Firmicutes,4HATG@91061|Bacilli,1ZCQY@1386|Bacillus 91061|Bacilli K FCD - - - - - - - - - - - - FCD,GntR k141_9494_1 42565.FP66_07285 7.84e-126 369.0 COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,1RMIX@1236|Gammaproteobacteria,1XH5P@135619|Oceanospirillales 135619|Oceanospirillales M zinc metalloprotease rseP - - ko:K11749 ko02024,ko04112,map02024,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - PDZ,PDZ_2,Peptidase_M50 k141_37694_1 868131.MSWAN_0705 4.98e-15 75.1 arCOG10178@1|root,arCOG10178@2157|Archaea,2XY0I@28890|Euryarchaeota 28890|Euryarchaeota S CAAX protease self-immunity - - - - - - - - - - - - Abi k141_21053_1 1117647.M5M_09020 5.96e-103 325.0 COG3118@1|root,COG3118@2|Bacteria,1QWQK@1224|Proteobacteria,1T5NR@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Sulfotransferase domain - - - - - - - - - - - - Sulfotransfer_3 k141_17500_1 1042377.AFPJ01000030_gene472 1.51e-120 358.0 COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,1RP7E@1236|Gammaproteobacteria,465AG@72275|Alteromonadaceae 1236|Gammaproteobacteria J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) gatA - 3.5.1.4,6.3.5.6,6.3.5.7 ko:K01426,ko:K02433 ko00330,ko00360,ko00380,ko00627,ko00643,ko00970,ko01100,ko01120,map00330,map00360,map00380,map00627,map00643,map00970,map01100,map01120 - R02540,R03096,R03180,R03905,R03909,R04212,R05551,R05590 RC00010,RC00100,RC00950,RC01025 ko00000,ko00001,ko01000,ko03029 - - - Amidase k141_26121_1 1202532.FF52_13676 5.37e-10 66.6 COG4247@1|root,COG4247@2|Bacteria,4NH2W@976|Bacteroidetes,1HX1S@117743|Flavobacteriia,2NTYC@237|Flavobacterium 976|Bacteroidetes I 3-phytase - - 3.1.3.8 ko:K01083 ko00562,map00562 - R03371 RC00078 ko00000,ko00001,ko01000 - - - Phytase k141_4495_1 218284.CCDN010000001_gene1465 2.06e-49 165.0 COG0604@1|root,COG0604@2|Bacteria,1TPGA@1239|Firmicutes,4HBKZ@91061|Bacilli,1ZDYJ@1386|Bacillus 91061|Bacilli C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases qor - 1.6.5.5 ko:K00344 - - - - ko00000,ko01000 - - - ADH_N,ADH_zinc_N k141_4495_2 218284.CCDN010000001_gene1464 1.83e-37 133.0 COG1024@1|root,COG1024@2|Bacteria,1TQ2V@1239|Firmicutes,4HBT0@91061|Bacilli,1ZE3C@1386|Bacillus 91061|Bacilli I Belongs to the enoyl-CoA hydratase isomerase family phaB GO:0003674,GO:0003824,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006635,GO:0006636,GO:0008150,GO:0008152,GO:0008610,GO:0009056,GO:0009058,GO:0009062,GO:0009987,GO:0016042,GO:0016053,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016860,GO:0016863,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0033559,GO:0034017,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:0072330,GO:1901575,GO:1901576 5.3.3.14,5.3.3.18 ko:K15866,ko:K18474 ko00061,ko00360,ko01120,map00061,map00360,map01120 - R07639,R09837,R09839 RC00004,RC00326,RC01078,RC02689,RC03003 ko00000,ko00001,ko01000,ko01004 - - - ECH_1 k141_16426_1 450851.PHZ_c0288 1.22e-63 210.0 COG2355@1|root,COG2355@2|Bacteria,1MWEW@1224|Proteobacteria,2TR5C@28211|Alphaproteobacteria,2KI2D@204458|Caulobacterales 204458|Caulobacterales E PFAM peptidase M19 renal dipeptidase - - 3.4.13.19 ko:K01273 - - - - ko00000,ko00537,ko01000,ko01002,ko04147 - - - Peptidase_M19 k141_37695_1 674977.VMC_17170 4.57e-16 73.2 COG2166@1|root,COG2166@2|Bacteria,1RI8F@1224|Proteobacteria,1S65C@1236|Gammaproteobacteria,1XX28@135623|Vibrionales 135623|Vibrionales S COG2166 SufE protein probably involved in Fe-S center assembly csdE - - ko:K02426 - - - - ko00000 - - - SufE k141_37695_2 223926.28807363 9.61e-32 120.0 COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,1RNIY@1236|Gammaproteobacteria,1XTR5@135623|Vibrionales 135623|Vibrionales E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine csdA GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769 2.8.1.7,4.4.1.16 ko:K01766,ko:K11717 ko00450,ko01100,map00450,map01100 - R03599,R11528 RC00961,RC01789,RC02313 ko00000,ko00001,ko01000 - - - Aminotran_5 k141_31597_1 218284.CCDN010000001_gene1276 1.1e-65 218.0 28RY4@1|root,30CEX@2|Bacteria,1U9S3@1239|Firmicutes,4IJYG@91061|Bacilli,1ZNUD@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_3292_1 218284.CCDN010000001_gene551 5.65e-181 525.0 COG0072@1|root,COG0072@2|Bacteria,1TP98@1239|Firmicutes,4HAQ9@91061|Bacilli,1ZB8G@1386|Bacillus 91061|Bacilli J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily pheT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - B3_4,B5,FDX-ACB,tRNA_bind k141_13026_6 1116375.VEJY3_04420 3.58e-156 440.0 COG0518@1|root,COG0518@2|Bacteria,1MV9U@1224|Proteobacteria,1S2MK@1236|Gammaproteobacteria,1XTR7@135623|Vibrionales 135623|Vibrionales F Glutamine amidotransferase class-I - - - - - - - - - - - - GATase k141_34304_1 1265503.KB905161_gene3099 1.96e-43 159.0 COG2755@1|root,COG2755@2|Bacteria,1R72J@1224|Proteobacteria,1RZ4I@1236|Gammaproteobacteria 1236|Gammaproteobacteria E lipolytic protein G-D-S-L family - - - - - - - - - - - - Lipase_GDSL_2,TPR_19 k141_36441_1 1157490.EL26_23480 1.23e-66 222.0 COG0621@1|root,COG0621@2|Bacteria,1TNYN@1239|Firmicutes,4HAAS@91061|Bacilli,27851@186823|Alicyclobacillaceae 91061|Bacilli J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine miaB GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035597,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360 2.8.4.3 ko:K06168 - - R10645,R10646,R10647 RC00003,RC00980,RC03221,RC03222 ko00000,ko01000,ko03016 - - - Radical_SAM,TRAM,UPF0004 k141_5911_1 1340493.JNIF01000003_gene2976 1.31e-18 86.3 COG0596@1|root,COG2976@1|root,COG0596@2|Bacteria,COG2976@2|Bacteria 2|Bacteria CO Protein conserved in bacteria - - - - - - - - - - - - Abhydrolase_1,Beta-lactamase,TPR_2,TPR_21,TPR_8 k141_4524_1 1042377.AFPJ01000027_gene2667 1.2e-111 343.0 COG3591@1|root,COG3591@2|Bacteria,1MX71@1224|Proteobacteria,1RRGG@1236|Gammaproteobacteria,465PD@72275|Alteromonadaceae 1236|Gammaproteobacteria E Peptidase S46 - - - - - - - - - - - - Peptidase_S46 k141_29545_1 218284.CCDN010000001_gene795 1.56e-95 286.0 COG3330@1|root,COG3330@2|Bacteria,1V2ZT@1239|Firmicutes,4I257@91061|Bacilli,1ZG55@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF4912) - - - ko:K09942 - - - - ko00000 - - - DUF4912 k141_30462_1 1307436.PBF_02560 7.5e-63 201.0 COG0306@1|root,COG0306@2|Bacteria,1TQ3D@1239|Firmicutes,4HAPD@91061|Bacilli,1ZBFE@1386|Bacillus 91061|Bacilli P phosphate transporter pit GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661 - ko:K03306 - - - - ko00000 2.A.20 - - PHO4 k141_30462_2 997296.PB1_03725 2.68e-32 117.0 COG1392@1|root,COG1392@2|Bacteria,1V2QG@1239|Firmicutes,4IRDK@91061|Bacilli,1ZRTN@1386|Bacillus 91061|Bacilli P COG1392 Phosphate transport regulator (distant homolog of PhoU) ykaA - - ko:K07220 - - - - ko00000 - - - PhoU_div k141_1160_2 1347086.CCBA010000030_gene166 4.96e-62 196.0 COG1399@1|root,COG1399@2|Bacteria,1VB08@1239|Firmicutes,4HME9@91061|Bacilli,1ZGJH@1386|Bacillus 91061|Bacilli S metal-binding, possibly nucleic acid-binding protein ylbN - - ko:K07040 - - - - ko00000 - - - DUF177 k141_1160_3 665959.HMPREF1013_00444 1.2e-33 116.0 COG0333@1|root,COG0333@2|Bacteria,1VEFI@1239|Firmicutes,4HNIZ@91061|Bacilli,1ZJ4F@1386|Bacillus 91061|Bacilli J Belongs to the bacterial ribosomal protein bL32 family rpmF GO:0003674,GO:0003735,GO:0005198 - ko:K02911 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_L32p k141_29546_1 218284.CCDN010000005_gene3462 1.27e-106 317.0 COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,4HA13@91061|Bacilli,1ZAWQ@1386|Bacillus 91061|Bacilli E Aminotransferase yugH - - ko:K10907 - - - - ko00000,ko01000,ko01007 - - - Aminotran_1_2 k141_21093_2 297246.lpp2330 3.33e-27 102.0 2E70X@1|root,331JP@2|Bacteria,1N81S@1224|Proteobacteria,1SCI0@1236|Gammaproteobacteria,1JEP9@118969|Legionellales 118969|Legionellales S Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - ko:K02116 - - - - ko00000,ko00194 3.A.2.1 - - ATPase_gene1 k141_21093_3 1283300.ATXB01000001_gene1562 6.98e-25 99.4 COG0355@1|root,COG0355@2|Bacteria,1N1NE@1224|Proteobacteria,1S9B5@1236|Gammaproteobacteria,1XFSN@135618|Methylococcales 135618|Methylococcales C ATP synthase, Delta/Epsilon chain, beta-sandwich domain - - - ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_DE_N k141_33029_2 1294265.JCM21738_4670 3.1e-80 247.0 COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,4HA13@91061|Bacilli,1ZAWQ@1386|Bacillus 91061|Bacilli E Aminotransferase patA - - ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 M00525 R04467 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k141_17555_2 1196031.ALEG01000047_gene174 4.3e-36 132.0 COG1404@1|root,COG1404@2|Bacteria,1TSRI@1239|Firmicutes,4HBFB@91061|Bacilli,1ZCQD@1386|Bacillus 91061|Bacilli O Subtilase family - - 3.4.21.62 ko:K01342 ko02024,map02024 - - - ko00000,ko00001,ko01000,ko01002,ko03110 - - - Peptidase_S8 k141_2075_1 1196031.ALEG01000067_gene4756 6.63e-97 291.0 COG1294@1|root,COG1294@2|Bacteria,1TPYX@1239|Firmicutes,4HA9T@91061|Bacilli,1ZCH6@1386|Bacillus 91061|Bacilli C COG1294 Cytochrome bd-type quinol oxidase, subunit 2 - - 1.10.3.14 ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - Cyt_bd_oxida_II k141_22582_1 856793.MICA_2202 6.12e-113 331.0 COG0657@1|root,COG0657@2|Bacteria,1N2XW@1224|Proteobacteria,2U3QT@28211|Alphaproteobacteria,4BT8C@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria I Carboxylesterase family - - - - - - - - - - - - Abhydrolase_3,COesterase,Peptidase_S9 k141_28146_1 1123073.KB899241_gene2027 3.48e-35 137.0 COG1361@1|root,COG1361@2|Bacteria,1QCRB@1224|Proteobacteria,1T8HR@1236|Gammaproteobacteria,1XAR7@135614|Xanthomonadales 135614|Xanthomonadales M Conserved repeat domain - - - - - - - - - - - - - k141_4526_1 986075.CathTA2_2526 9.39e-37 127.0 COG0197@1|root,COG0197@2|Bacteria,1V1AY@1239|Firmicutes,4HFPN@91061|Bacilli 91061|Bacilli J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs rplP GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - ko:K02878 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L16 k141_4526_2 1379701.JPJC01000017_gene3310 1.12e-41 144.0 COG0092@1|root,COG0092@2|Bacteria,1MUAI@1224|Proteobacteria,2TRZ2@28211|Alphaproteobacteria,2K04S@204457|Sphingomonadales 204457|Sphingomonadales J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation rpsC - - ko:K02982 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KH_2,Ribosomal_S3_C k141_24839_1 1279017.AQYJ01000029_gene3747 3.6e-283 793.0 COG3387@1|root,COG3387@2|Bacteria,1MW9J@1224|Proteobacteria,1T2G2@1236|Gammaproteobacteria,465X7@72275|Alteromonadaceae 1236|Gammaproteobacteria G PFAM Glycoside hydrolase 15-related - - - - - - - - - - - - F5_F8_type_C,GDE_C k141_24839_3 402881.Plav_2386 7.14e-27 109.0 COG3637@1|root,COG3637@2|Bacteria,1QUUK@1224|Proteobacteria,2TW8A@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Alginate export - - - - - - - - - - - - Alginate_exp k141_36443_1 1034943.BN1094_02759 7.21e-72 236.0 COG2015@1|root,COG2015@2|Bacteria,1MU82@1224|Proteobacteria,1RMHR@1236|Gammaproteobacteria,1JDYK@118969|Legionellales 118969|Legionellales Q Alkyl sulfatase dimerisation - - - - - - - - - - - - Alkyl_sulf_C,Alkyl_sulf_dimr,Lactamase_B k141_22583_1 218284.CCDN010000001_gene1893 6.78e-130 405.0 COG2176@1|root,COG2176@2|Bacteria,1TPAG@1239|Firmicutes,4H9RF@91061|Bacilli,1ZCIB@1386|Bacillus 91061|Bacilli L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity polC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.7.7 ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_a_NI,DNA_pol3_a_NII,DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon k141_17556_1 446468.Ndas_3844 1.94e-40 153.0 COG0737@1|root,COG0737@2|Bacteria,2GKC3@201174|Actinobacteria,4EHCF@85012|Streptosporangiales 201174|Actinobacteria F 5'-nucleotidase, C-terminal domain cpdB - 3.1.3.5,3.1.3.6,3.1.4.16 ko:K01081,ko:K01119 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01562,R01569,R01664,R01877,R01968,R02088,R02102,R02148,R02323,R02370,R02719,R03346,R03537,R03538,R03929,R05135 RC00017,RC00078,RC00296 ko00000,ko00001,ko01000 - - - 5_nucleotid_C,Metallophos k141_35623_2 223926.28809781 2.82e-56 178.0 2AWHT@1|root,31NEC@2|Bacteria,1QK5C@1224|Proteobacteria,1TI8I@1236|Gammaproteobacteria,1XYMZ@135623|Vibrionales 135623|Vibrionales S VanZ like family - - - ko:K20950 ko05111,map05111 - - - ko00000,ko00001 - - - VanZ k141_35623_3 1116375.VEJY3_23151 1.43e-231 647.0 COG2244@1|root,COG2244@2|Bacteria,1MWKV@1224|Proteobacteria,1S4AZ@1236|Gammaproteobacteria,1XWQF@135623|Vibrionales 135623|Vibrionales S Membrane protein involved in the export of O-antigen and teichoic acid - - - - - - - - - - - - Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C k141_10534_1 1116375.VEJY3_19776 3.41e-99 302.0 COG3288@1|root,COG3288@2|Bacteria,1MVXU@1224|Proteobacteria,1RN23@1236|Gammaproteobacteria,1XU8J@135623|Vibrionales 135623|Vibrionales C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane pntA - 1.6.1.2 ko:K00324 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - AlaDh_PNT_C,AlaDh_PNT_N,PNTB_4TM k141_10534_2 1116375.VEJY3_19771 6.45e-53 167.0 COG5453@1|root,COG5453@2|Bacteria,1N7WA@1224|Proteobacteria,1SE7G@1236|Gammaproteobacteria,1Y2B9@135623|Vibrionales 135623|Vibrionales S Transcriptional activator HlyU - - - - - - - - - - - - HlyU k141_10534_3 1280001.BAOA01000138_gene2010 5.27e-59 184.0 2E4HY@1|root,33HKA@2|Bacteria,1NIGQ@1224|Proteobacteria,1SHKJ@1236|Gammaproteobacteria,1XXT7@135623|Vibrionales 135623|Vibrionales S Late competence development protein ComFB - - - - - - - - - - - - ComFB k141_10534_4 1280001.BAOA01000138_gene2006 3.78e-155 443.0 COG4206@1|root,COG4206@2|Bacteria,1RKV8@1224|Proteobacteria,1S75K@1236|Gammaproteobacteria,1XUT9@135623|Vibrionales 135623|Vibrionales H Solitary outer membrane autotransporter beta-barrel domain - - - - - - - - - - - - Omp_AT k141_10534_5 223926.28809229 3.23e-91 268.0 2CB6X@1|root,2ZTSF@2|Bacteria,1P8T9@1224|Proteobacteria,1STHQ@1236|Gammaproteobacteria,1XX1M@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF3069) VPA0928 - - - - - - - - - - - DUF3069 k141_10534_6 674977.VMC_32360 3.57e-217 605.0 COG4148@1|root,COG4148@2|Bacteria,1MU8K@1224|Proteobacteria,1RQCV@1236|Gammaproteobacteria,1XT5C@135623|Vibrionales 135623|Vibrionales P Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system modC GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015098,GO:0015103,GO:0015318,GO:0015399,GO:0015405,GO:0015412,GO:0015689,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0042623,GO:0042626,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0099133 3.6.3.29 ko:K02017 ko02010,map02010 M00189 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.8 - - ABC_tran,TOBE k141_10534_7 223926.28809231 3.6e-145 411.0 COG4149@1|root,COG4149@2|Bacteria,1MUXR@1224|Proteobacteria,1RRDV@1236|Gammaproteobacteria,1XSFP@135623|Vibrionales 135623|Vibrionales P COG4149 ABC-type molybdate transport system, permease component modB - - ko:K02018 ko02010,map02010 M00189 - - ko00000,ko00001,ko00002,ko02000 3.A.1.8 - - BPD_transp_1 k141_10534_8 223926.28809232 1.18e-140 401.0 COG0725@1|root,COG0725@2|Bacteria,1MVNA@1224|Proteobacteria,1RN71@1236|Gammaproteobacteria,1XVU1@135623|Vibrionales 135623|Vibrionales P Molybdenum ABC transporter, periplasmic molybdenum-binding protein modA - - ko:K02020 ko02010,map02010 M00189 - - ko00000,ko00001,ko00002,ko02000 3.A.1.8 - - SBP_bac_11 k141_28147_1 218284.CCDN010000001_gene1357 4.82e-131 391.0 COG0514@1|root,COG0514@2|Bacteria,1TPN5@1239|Firmicutes,4H9QP@91061|Bacilli,1ZC4U@1386|Bacillus 91061|Bacilli L DNA helicase recQ GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009378,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.6.4.12 ko:K03654 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind k141_17557_1 218284.CCDN010000001_gene253 4.24e-105 330.0 COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,4HAWB@91061|Bacilli,1ZAQK@1386|Bacillus 91061|Bacilli J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS - 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1 k141_33031_1 315730.BcerKBAB4_0164 2.67e-92 286.0 COG0277@1|root,COG0277@2|Bacteria,1UIU4@1239|Firmicutes,4HBGZ@91061|Bacilli,1ZD7D@1386|Bacillus 91061|Bacilli C D-arabinono-1,4-lactone oxidase yitY - - - - - - - - - - - ALO,FAD_binding_4 k141_34306_3 1294265.JCM21738_268 6.73e-45 145.0 COG1837@1|root,COG1837@2|Bacteria,1VEG7@1239|Firmicutes,4HNX0@91061|Bacilli,1ZIW7@1386|Bacillus 91061|Bacilli S Belongs to the UPF0109 family ylqC - - ko:K06960 - - - - ko00000 - - - KH_4 k141_4528_1 545693.BMQ_3977 6.44e-71 222.0 COG2514@1|root,COG2514@2|Bacteria,1TPRF@1239|Firmicutes,4HAE7@91061|Bacilli,1ZAQI@1386|Bacillus 91061|Bacilli S glyoxalase catE - 1.13.11.2 ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 M00569 R00816,R04089,R05295,R05404,R05406,R07795 RC00387,RC00643,RC01075,RC01364,RC01914 ko00000,ko00001,ko00002,ko01000 - - - Glyoxalase k141_31606_1 225849.swp_4872 9.51e-104 311.0 COG0729@1|root,COG0729@2|Bacteria 2|Bacteria M surface antigen - - - ko:K07277,ko:K07278 - - - - ko00000,ko02000,ko03029 1.B.33,1.B.33.2.4 - - Bac_surface_Ag,POTRA,Peptidase_S74 k141_32020_1 421052.F945_00130 6.05e-40 142.0 COG2267@1|root,COG2267@2|Bacteria,1R7QW@1224|Proteobacteria,1S2X8@1236|Gammaproteobacteria,3NMX6@468|Moraxellaceae 1236|Gammaproteobacteria I carboxylic ester hydrolase activity - - - - - - - - - - - - - k141_32020_3 1515746.HR45_07250 2.2e-242 697.0 COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,1S0X9@1236|Gammaproteobacteria,2QBEN@267890|Shewanellaceae 1236|Gammaproteobacteria L Helix-hairpin-helix containing domain VPA1266 - 3.1.11.5 ko:K03581 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_30,HHH_4,UvrD_C_2,Viral_helicase1 k141_30861_1 1121931.AUHG01000010_gene508 3.06e-06 53.9 2E3AK@1|root,2ZCCU@2|Bacteria,4NN6G@976|Bacteroidetes,1I1MB@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - k141_30862_2 1279017.AQYJ01000024_gene1175 8.06e-26 100.0 COG0278@1|root,COG0278@2|Bacteria,1MZ4V@1224|Proteobacteria,1S640@1236|Gammaproteobacteria,466TX@72275|Alteromonadaceae 1236|Gammaproteobacteria C Belongs to the glutaredoxin family. Monothiol subfamily grxD - - ko:K07390 - - - - ko00000,ko03029,ko03110 - - - Glutaredoxin,Rhodanese k141_32023_1 1078085.HMPREF1210_02147 2.6e-85 292.0 COG1404@1|root,COG1404@2|Bacteria,1TPH1@1239|Firmicutes,4HBQH@91061|Bacilli 91061|Bacilli O Belongs to the peptidase S8 family prtS - 3.4.21.110,3.4.21.96 ko:K01361,ko:K08652 - - - - ko00000,ko01000,ko01002,ko03110 - - - FIVAR,Gram_pos_anchor,Inhibitor_I9,PA,Peptidase_S8,SLH,YSIRK_signal,fn3_5 k141_32024_1 1294265.JCM21738_5226 1.44e-42 141.0 COG0824@1|root,COG0824@2|Bacteria,1VAGM@1239|Firmicutes,4HIVC@91061|Bacilli,1ZG6C@1386|Bacillus 91061|Bacilli S thioesterase yneP - - ko:K07107 - - - - ko00000,ko01000 - - - 4HBT,4HBT_2 k141_32024_2 1294265.JCM21738_5227 7.67e-62 190.0 2CICC@1|root,32S7S@2|Bacteria,1VC46@1239|Firmicutes,4HKPJ@91061|Bacilli,1ZI00@1386|Bacillus 91061|Bacilli - - yneQ - - - - - - - - - - - - k141_32024_3 1294265.JCM21738_5228 3.82e-32 112.0 COG4841@1|root,COG4841@2|Bacteria,1VEQE@1239|Firmicutes,4HNU2@91061|Bacilli,1ZHU4@1386|Bacillus 91061|Bacilli S Belongs to the HesB IscA family yneR - - - - - - - - - - - Fe-S_biosyn k141_30865_2 218284.CCDN010000002_gene2083 1.75e-161 462.0 COG1541@1|root,COG1541@2|Bacteria,1TQA1@1239|Firmicutes,4HAU0@91061|Bacilli,1ZBRF@1386|Bacillus 91061|Bacilli H Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) paaK - 6.2.1.30 ko:K01912 ko00360,ko01120,ko05111,map00360,map01120,map05111 - R02539 RC00004,RC00014 ko00000,ko00001,ko01000 - - - AMP-binding,AMP-binding_C_2 k141_30867_1 1121938.AUDY01000009_gene2321 2.49e-20 91.3 COG0591@1|root,COG0591@2|Bacteria,1TQCK@1239|Firmicutes,4HB5K@91061|Bacilli 91061|Bacilli E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - ko:K03307 - - - - ko00000 2.A.21 - - SSF k141_32025_1 1294265.JCM21738_1708 3.23e-34 130.0 COG1113@1|root,COG1113@2|Bacteria,1TP97@1239|Firmicutes,4H9QX@91061|Bacilli,1ZDGG@1386|Bacillus 91061|Bacilli E COG1113 Gamma-aminobutyrate permease and related permeases ycgH GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03293 - - - - ko00000 2.A.3.1 - - AA_permease k141_32025_2 265729.GS18_0201755 1.48e-123 360.0 COG1834@1|root,COG1834@2|Bacteria,1VDT8@1239|Firmicutes,4ISAW@91061|Bacilli,1ZCTN@1386|Bacillus 91061|Bacilli E Amidinotransferase ykgA - - - - - - - - - - - Amidinotransf k141_32025_3 1121929.KB898669_gene3252 1.76e-23 95.1 2E4BW@1|root,32Z7G@2|Bacteria,1VH0F@1239|Firmicutes,4HPQD@91061|Bacilli,4716D@74385|Gracilibacillus 91061|Bacilli S Protein of unknown function (DUF2512) yndM - - - - - - - - - - - DUF2512 k141_32026_1 1042377.AFPJ01000036_gene1155 9.99e-54 177.0 COG1737@1|root,COG1737@2|Bacteria,1ND5W@1224|Proteobacteria,1RNCI@1236|Gammaproteobacteria,4675C@72275|Alteromonadaceae 1236|Gammaproteobacteria K Helix-turn-helix domain, rpiR family yfhH GO:0003674,GO:0003700,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K15835 - - - - ko00000,ko03000 - - - HTH_6,SIS k141_30870_1 314275.MADE_1005700 1.99e-80 246.0 COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,1RMFK@1236|Gammaproteobacteria,4648H@72275|Alteromonadaceae 1236|Gammaproteobacteria NT Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP cheR GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0050896 2.1.1.80 ko:K00575 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko01000,ko02035 - - - CheR,CheR_N k141_30871_1 717605.Theco_3548 3.56e-15 78.2 COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,4HDVU@91061|Bacilli,26W4Z@186822|Paenibacillaceae 91061|Bacilli F Adenylosuccinate lyase C-terminus - - 4.3.2.2,5.5.1.2 ko:K01756,ko:K01857 ko00230,ko00250,ko00362,ko01100,ko01110,ko01120,ko01130,ko01220,map00230,map00250,map00362,map01100,map01110,map01120,map01130,map01220 M00048,M00049 R01083,R03307,R04559 RC00379,RC00444,RC00445,RC00902 ko00000,ko00001,ko00002,ko01000 - - - ADSL_C,Lyase_1 k141_32028_1 1453501.JELR01000001_gene3274 2.26e-60 195.0 2BZVX@1|root,32R5V@2|Bacteria,1RKXP@1224|Proteobacteria,1T470@1236|Gammaproteobacteria,468AV@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_30873_2 1453501.JELR01000002_gene1338 3.24e-41 142.0 COG3637@1|root,COG3637@2|Bacteria,1RDPZ@1224|Proteobacteria,1S4GQ@1236|Gammaproteobacteria,467IM@72275|Alteromonadaceae 1236|Gammaproteobacteria M Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - - - - - - - - - - OMP_b-brl k141_32030_2 1295642.H839_02301 8.25e-93 286.0 COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,4HAJM@91061|Bacilli,1WE7Z@129337|Geobacillus 91061|Bacilli P ATPases associated with a variety of cellular activities M1-1085 - - ko:K16786,ko:K16787 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran k141_30874_1 1453501.JELR01000002_gene115 2.41e-117 368.0 COG0587@1|root,COG0587@2|Bacteria,1MUE4@1224|Proteobacteria,1RQA8@1236|Gammaproteobacteria,464B5@72275|Alteromonadaceae 1236|Gammaproteobacteria L DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase dnaE2 GO:0003674,GO:0003824,GO:0003887,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K14162 - - - - ko00000,ko01000,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon k141_30874_2 1453501.JELR01000002_gene113 2.51e-126 374.0 COG0389@1|root,COG0389@2|Bacteria,1MU5X@1224|Proteobacteria,1S28B@1236|Gammaproteobacteria,465IA@72275|Alteromonadaceae 1236|Gammaproteobacteria L Nucleotidyltransferase DNA polymerase involved in DNA repair imuB - - ko:K14161 - - - - ko00000,ko03400 - - - IMS k141_30875_2 1453501.JELR01000001_gene2588 2.53e-08 53.9 COG3713@1|root,COG4704@1|root,COG3713@2|Bacteria,COG4704@2|Bacteria 2|Bacteria M MltA-interacting MipA family protein mipA - - ko:K07274 - - - - ko00000,ko02000 9.B.99.1 - - DUF2141,MipA k141_32034_1 1116375.VEJY3_19441 1.88e-34 129.0 COG0446@1|root,COG0446@2|Bacteria,1MXA9@1224|Proteobacteria,1RYAH@1236|Gammaproteobacteria,1Y2J3@135623|Vibrionales 135623|Vibrionales C BFD-like [2Fe-2S] binding domain - - - - - - - - - - - - Fer2_BFD,Pyr_redox_2 k141_32034_2 945550.VISI1226_03385 3.73e-48 155.0 COG1034@1|root,COG1034@2|Bacteria,1PH0T@1224|Proteobacteria,1TAXZ@1236|Gammaproteobacteria,1Y1AE@135623|Vibrionales 135623|Vibrionales C 2Fe-2S iron-sulfur cluster binding domain - - - - - - - - - - - - Fer2_4 k141_32034_3 1116375.VEJY3_19431 4.26e-195 546.0 COG0665@1|root,COG0665@2|Bacteria,1MVM6@1224|Proteobacteria,1RRHH@1236|Gammaproteobacteria,1XZAR@135623|Vibrionales 135623|Vibrionales E FAD dependent oxidoreductase - - - - - - - - - - - - DAO k141_30879_1 1042377.AFPJ01000005_gene2447 6.01e-14 71.2 COG0025@1|root,COG0025@2|Bacteria,1MW5T@1224|Proteobacteria,1RPH6@1236|Gammaproteobacteria,464FP@72275|Alteromonadaceae 1236|Gammaproteobacteria P Sodium/hydrogen exchanger family nhaP - - ko:K03316 - - - - ko00000 2.A.36 - - Na_H_Exchanger k141_32037_2 1415780.JPOG01000001_gene3291 7.86e-15 75.9 COG0810@1|root,COG0810@2|Bacteria,1PEDH@1224|Proteobacteria,1RRNT@1236|Gammaproteobacteria 1236|Gammaproteobacteria U Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - ko:K03832 - - - - ko00000,ko02000 2.C.1.1 - - TonB_C k141_30881_1 218284.CCDN010000007_gene3907 6.8e-212 596.0 COG3852@1|root,COG3852@2|Bacteria,1TRH0@1239|Firmicutes,4HD4A@91061|Bacilli,1ZARI@1386|Bacillus 91061|Bacilli T COG0642 Signal transduction histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,PAS,PAS_4,PAS_9 k141_32041_1 1279017.AQYJ01000026_gene265 1.35e-35 133.0 COG0438@1|root,COG0438@2|Bacteria,1NA28@1224|Proteobacteria,1RQBV@1236|Gammaproteobacteria,4668K@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0438 Glycosyltransferase - - - - - - - - - - - - DUF3524,Glyco_trans_1_4,Glycos_transf_1 k141_30883_1 986075.CathTA2_0562 1.56e-99 298.0 COG0834@1|root,COG0834@2|Bacteria,1UXYA@1239|Firmicutes,4H9NJ@91061|Bacilli 91061|Bacilli ET ABC transporter, substratebinding protein - - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 k141_30884_2 861299.J421_0687 3.47e-72 229.0 COG1834@1|root,COG1834@2|Bacteria,1ZUVY@142182|Gemmatimonadetes 142182|Gemmatimonadetes E Amidinotransferase - - 3.5.3.18 ko:K01482 - - - - ko00000,ko01000,ko04147 - - - Amidinotransf k141_32046_2 697282.Mettu_2076 1.07e-38 136.0 COG1192@1|root,COG1192@2|Bacteria,1R62T@1224|Proteobacteria,1S58J@1236|Gammaproteobacteria,1XG72@135618|Methylococcales 135618|Methylococcales D Cellulose biosynthesis protein BcsQ - - - - - - - - - - - - AAA_31 k141_30886_1 1453501.JELR01000002_gene517 1.15e-104 311.0 COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,1RMKY@1236|Gammaproteobacteria,464WM@72275|Alteromonadaceae 1236|Gammaproteobacteria H Belongs to the FPP GGPP synthase family ispA GO:0003674,GO:0003824,GO:0004161,GO:0004337,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016114,GO:0016740,GO:0016765,GO:0019637,GO:0033383,GO:0033384,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0045337,GO:0045338,GO:0071704,GO:0090407,GO:1901576 2.5.1.1,2.5.1.10,2.5.1.29 ko:K00795,ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00366 R01658,R02003,R02061 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 - - iPC815.YPO3176,iSFV_1184.SFV_0386 polyprenyl_synt k141_30886_3 1453501.JELR01000002_gene529 4.58e-28 114.0 COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,1RMT7@1236|Gammaproteobacteria,466B9@72275|Alteromonadaceae 1236|Gammaproteobacteria S Bacterial protein of unknown function (DUF885) - - - - - - - - - - - - DUF885 k141_30890_2 218284.CCDN010000010_gene4390 2.49e-34 123.0 COG1211@1|root,COG1211@2|Bacteria,1V3M7@1239|Firmicutes,4HH2N@91061|Bacilli,1ZCWR@1386|Bacillus 91061|Bacilli I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) ispD GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05633 RC00002 ko00000,ko00001,ko00002,ko01000 - - - IspD k141_30891_1 1216007.AOPM01000026_gene3251 5.18e-105 317.0 COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,1RN2V@1236|Gammaproteobacteria,2Q1UC@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria P Sulfatase - - 3.1.6.1 ko:K01130 ko00140,ko00600,map00140,map00600 - R03980,R04856 RC00128,RC00231 ko00000,ko00001,ko01000 - - - Sulfatase,Sulfatase_C k141_30892_1 1385511.N783_03225 2.34e-37 145.0 COG4325@1|root,COG4325@2|Bacteria,1TSID@1239|Firmicutes,4HDM1@91061|Bacilli,2Y91P@289201|Pontibacillus 91061|Bacilli S Predicted membrane protein (DUF2254) - - - - - - - - - - - - DUF2254 k141_30893_1 218284.CCDN010000001_gene1926 9.63e-39 141.0 COG3144@1|root,COG3144@2|Bacteria,1VI6B@1239|Firmicutes,4HGUR@91061|Bacilli,1ZJ6D@1386|Bacillus 91061|Bacilli N Flagellar hook-length control fliK GO:0001539,GO:0006928,GO:0008150,GO:0009987,GO:0040011,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588 - ko:K02414 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_hook k141_30893_2 1307436.PBF_07496 4.38e-23 93.6 COG1843@1|root,COG1843@2|Bacteria,1VF85@1239|Firmicutes,4HNQK@91061|Bacilli,1ZI5S@1386|Bacillus 91061|Bacilli N Flagellar basal body rod modification protein flgD GO:0001539,GO:0005575,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009424,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588 - ko:K02389 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FlgD k141_30894_2 1121468.AUBR01000004_gene109 3.4e-11 63.9 COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,2490S@186801|Clostridia,42F49@68295|Thermoanaerobacterales 186801|Clostridia L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids dnaA - - ko:K02313 ko02020,ko04112,map02020,map04112 - - - ko00000,ko00001,ko03032,ko03036 - - - Bac_DnaA,Bac_DnaA_C,DnaA_N k141_30896_1 666686.B1NLA3E_10500 4.42e-54 172.0 COG0450@1|root,COG0450@2|Bacteria,1TQU7@1239|Firmicutes,4HWRE@91061|Bacilli,1ZFW9@1386|Bacillus 91061|Bacilli O AhpC/TSA family - - 1.11.1.15 ko:K03386 ko04214,map04214 - - - ko00000,ko00001,ko01000,ko04147 - - - 1-cysPrx_C,AhpC-TSA k141_30896_2 36331.EPrPI00000019874 3.63e-07 52.8 COG0450@1|root,COG0526@1|root,KOG0852@2759|Eukaryota,KOG0907@2759|Eukaryota,1MCEY@121069|Pythiales 121069|Pythiales O Thioredoxin-dependent peroxide reductase. Source PGD - - - - - - - - - - - - 1-cysPrx_C,AhpC-TSA,Thioredoxin k141_32047_1 518766.Rmar_2049 1.31e-43 169.0 COG1506@1|root,COG2706@1|root,COG1506@2|Bacteria,COG2706@2|Bacteria,4PIC9@976|Bacteroidetes,1FKAR@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes E 6-phosphogluconolactonase activity - - - - - - - - - - - - - k141_32047_4 1042377.AFPJ01000032_gene2761 3.23e-125 362.0 COG2188@1|root,COG2188@2|Bacteria,1MVFM@1224|Proteobacteria,1RNPE@1236|Gammaproteobacteria,466EK@72275|Alteromonadaceae 1236|Gammaproteobacteria K histidine utilization repressor hutC - - ko:K05836 - - - - ko00000,ko03000 - - - GntR,UTRA k141_30897_1 218284.CCDN010000005_gene3291 2.16e-182 521.0 COG1164@1|root,COG1164@2|Bacteria,1TP4P@1239|Firmicutes,4HA7X@91061|Bacilli,1ZCHA@1386|Bacillus 91061|Bacilli E oligoendopeptidase F pepF GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - ko:K08602 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M3,Peptidase_M3_N k141_30898_1 1453501.JELR01000001_gene1805 2.94e-128 374.0 COG0208@1|root,COG0208@2|Bacteria,1MWUS@1224|Proteobacteria,1RMJC@1236|Gammaproteobacteria,4649Z@72275|Alteromonadaceae 1236|Gammaproteobacteria F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdB - 1.17.4.1 ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - iJN746.PP_1177 Ribonuc_red_sm k141_30900_1 1294265.JCM21738_2928 1.44e-37 139.0 COG4717@1|root,COG4717@2|Bacteria,1TQP3@1239|Firmicutes,4HBCA@91061|Bacilli,1ZDHB@1386|Bacillus 91061|Bacilli L AAA domain yhaN - - - - - - - - - - - AAA_27 k141_30900_2 1294265.JCM21738_2929 7.39e-79 242.0 COG3481@1|root,COG3481@2|Bacteria,1TPIU@1239|Firmicutes,4HB1M@91061|Bacilli,1ZB1G@1386|Bacillus 91061|Bacilli L Shows a 3'-5' exoribonuclease activity yhaM GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031123,GO:0031125,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - ko:K03698 - - - - ko00000,ko01000,ko03019 - - - HD,tRNA_anti-codon k141_32048_1 218284.CCDN010000001_gene168 1.35e-146 417.0 COG0668@1|root,COG0668@2|Bacteria,1TR9Z@1239|Firmicutes,4HCB8@91061|Bacilli,1ZCW4@1386|Bacillus 91061|Bacilli M Mechanosensitive ion channel ykuT GO:0003674,GO:0005215,GO:0006810,GO:0006950,GO:0006970,GO:0008150,GO:0008381,GO:0009628,GO:0009987,GO:0015267,GO:0022803,GO:0022836,GO:0022857,GO:0033554,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071214,GO:0071470,GO:0104004 - ko:K22044 - - - - ko00000,ko02000 1.A.23.3 - - MS_channel k141_9523_2 1452718.JBOY01000005_gene3337 3.87e-57 184.0 COG0625@1|root,COG0625@2|Bacteria,1MY47@1224|Proteobacteria,1RRI3@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Belongs to the GST superfamily - - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C,GST_C_2,GST_C_3,GST_N,GST_N_2,GST_N_3 k141_15482_2 218284.CCDN010000001_gene277 6.88e-36 131.0 COG4565@1|root,COG4565@2|Bacteria,1TS2Z@1239|Firmicutes,4HCJ5@91061|Bacilli,1ZANG@1386|Bacillus 91061|Bacilli KT transcriptional regulatory protein - - - - - - - - - - - - HTH_11 k141_5969_1 1042377.AFPJ01000007_gene1790 2.23e-94 304.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MWKN@1224|Proteobacteria,1T3IM@1236|Gammaproteobacteria,465P2@72275|Alteromonadaceae 1236|Gammaproteobacteria P TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_3594_1 218284.CCDN010000004_gene3067 4.96e-70 214.0 COG2905@1|root,COG2905@2|Bacteria,1VW3X@1239|Firmicutes,4HJ81@91061|Bacilli,1ZH6S@1386|Bacillus 91061|Bacilli T COG0517 FOG CBS domain ylbB - - - - - - - - - - - CBS k141_21427_1 218284.CCDN010000001_gene196 5.75e-99 291.0 COG0603@1|root,COG0603@2|Bacteria,1TP4Z@1239|Firmicutes,4HB1Y@91061|Bacilli,1ZCJD@1386|Bacillus 91061|Bacilli F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) queC - 6.3.4.20 ko:K06920 ko00790,ko01100,map00790,map01100 - R09978 RC00959 ko00000,ko00001,ko01000,ko03016 - - - QueC k141_21427_2 218284.CCDN010000001_gene195 3.61e-81 242.0 COG0720@1|root,COG0720@2|Bacteria,1V6X6@1239|Firmicutes,4HJ9P@91061|Bacilli,1ZDDT@1386|Bacillus 91061|Bacilli H synthase queD - 4.1.2.50,4.2.3.12 ko:K01737 ko00790,ko01100,map00790,map01100 M00842,M00843 R04286,R09959 RC01117,RC02846,RC02847 ko00000,ko00001,ko00002,ko01000,ko03016 - - - PTPS k141_35684_1 1279017.AQYJ01000024_gene952 2.29e-89 270.0 COG1028@1|root,COG1028@2|Bacteria,1RAEZ@1224|Proteobacteria,1S615@1236|Gammaproteobacteria,467FQ@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - - - - - - - - - - adh_short k141_19041_1 1294265.JCM21738_1889 5.95e-22 89.0 COG1514@1|root,COG1514@2|Bacteria,1V2F3@1239|Firmicutes,4HG6P@91061|Bacilli,1ZG9R@1386|Bacillus 91061|Bacilli J Belongs to the 2H phosphoesterase superfamily. YjcG family yjcG - - - - - - - - - - - 2_5_RNA_ligase2 k141_19041_2 1294265.JCM21738_1890 5.43e-88 259.0 COG2153@1|root,COG2153@2|Bacteria,1VA2J@1239|Firmicutes,4HKF5@91061|Bacilli,1ZH1Q@1386|Bacillus 91061|Bacilli S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases yjcF GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0016747 - - - - - - - - - - Acetyltransf_10 k141_22604_1 696369.KI912183_gene420 2.04e-81 257.0 COG4584@1|root,COG4584@2|Bacteria,1TNY9@1239|Firmicutes,24B59@186801|Clostridia,263RC@186807|Peptococcaceae 186801|Clostridia L Integrase core domain - - - - - - - - - - - - rve k141_36870_1 1034347.CAHJ01000023_gene3278 5.68e-75 251.0 COG0737@1|root,COG1404@1|root,COG2374@1|root,COG4085@1|root,COG0737@2|Bacteria,COG1404@2|Bacteria,COG2374@2|Bacteria,COG4085@2|Bacteria,1TPV2@1239|Firmicutes,4HB9S@91061|Bacilli,1ZAY0@1386|Bacillus 91061|Bacilli F Belongs to the 5'-nucleotidase family yfkN - 3.1.3.5,3.1.3.6,3.1.4.16 ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01562,R01569,R01664,R01877,R01968,R02088,R02102,R02148,R02370,R02719,R03537,R03538,R03929,R05135 RC00017,RC00078,RC00296 ko00000,ko00001,ko01000 - - iYO844.BSU07840 5_nucleotid_C,Metallophos k141_4784_1 218284.CCDN010000002_gene2644 4.7e-112 333.0 COG3037@1|root,COG3037@2|Bacteria,1TQK5@1239|Firmicutes,4HBAD@91061|Bacilli,1ZCA9@1386|Bacillus 91061|Bacilli S PTS system ascorbate-specific transporter subunit IIC ulaA - - ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 M00283,M00550 R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.7.1 - - EIIC-GAT k141_32110_4 1279017.AQYJ01000027_gene1788 0.0 1084.0 COG4772@1|root,COG4772@2|Bacteria,1MWDG@1224|Proteobacteria,1RQA5@1236|Gammaproteobacteria,464IF@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG4772 Outer membrane receptor for Fe3 -dicitrate fecA - - ko:K16091 - - - - ko00000,ko02000 1.B.14.1.14 - - Plug,TonB_dep_Rec k141_21428_1 218284.CCDN010000002_gene2821 3.59e-77 235.0 COG0745@1|root,COG0745@2|Bacteria,1TSWT@1239|Firmicutes,4HBSC@91061|Bacilli,1ZCSV@1386|Bacillus 91061|Bacilli T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain hssR - - ko:K02483 - - - - ko00000,ko02022 - - - Response_reg,Trans_reg_C k141_8353_1 1453501.JELR01000002_gene613 9.97e-56 179.0 2DZ4B@1|root,34CDM@2|Bacteria,1PAEV@1224|Proteobacteria,1SV2F@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF4136) - - - - - - - - - - - - DUF4136 k141_34498_1 861299.J421_1490 7.02e-155 454.0 COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1ZSVF@142182|Gemmatimonadetes 142182|Gemmatimonadetes C Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg - - 1.2.7.11,1.2.7.3 ko:K00174 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - POR,POR_N k141_17846_1 218284.CCDN010000001_gene1189 1.86e-136 394.0 COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,4HBDP@91061|Bacilli,1ZAYG@1386|Bacillus 91061|Bacilli S protein conserved in bacteria - - - - - - - - - - - - DegV k141_26180_1 1121878.AUGL01000024_gene3745 1.67e-82 271.0 COG1629@1|root,COG4206@1|root,COG4206@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Receptor - - - - - - - - - - - - Plug,TonB_dep_Rec k141_4785_1 935837.JAEK01000040_gene3721 1.31e-47 169.0 COG2200@1|root,COG3300@1|root,COG2200@2|Bacteria,COG3300@2|Bacteria,1TS8B@1239|Firmicutes,4ISKA@91061|Bacilli,1ZDC3@1386|Bacillus 91061|Bacilli T Bacterial signalling protein N terminal repeat - - 2.7.7.65 ko:K21023 ko02025,map02025 - - - ko00000,ko00001,ko01000 - - - EAL,GAF,GGDEF,MASE3,MHYT,PAS_4,PAS_9 k141_13100_1 1122132.AQYH01000006_gene3672 1.86e-91 281.0 COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,2TUMJ@28211|Alphaproteobacteria,4BDSM@82115|Rhizobiaceae 28211|Alphaproteobacteria E Aminotransferase class-V - - - - - - - - - - - - Aminotran_5 k141_8354_1 1122135.KB893166_gene2892 1.39e-23 94.0 COG0698@1|root,COG0698@2|Bacteria,1RHBF@1224|Proteobacteria,2U94R@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Ribose 5-phosphate isomerase rpiB - 5.3.1.6 ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01056,R09030 RC00376,RC00434 ko00000,ko00001,ko00002,ko01000 - - - LacAB_rpiB k141_8354_2 1122947.FR7_3825 1.35e-20 92.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,4H63H@909932|Negativicutes 909932|Negativicutes C Belongs to the Glu Leu Phe Val dehydrogenases family gdh - 1.4.1.2,1.4.1.4 ko:K00260,ko:K00262 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 - R00243,R00248 RC00006,RC02799 ko00000,ko00001,ko01000 - - - ELFV_dehydrog,ELFV_dehydrog_N k141_21429_1 479433.Caci_4732 2.17e-06 48.9 COG1975@1|root,COG1975@2|Bacteria,2GIZS@201174|Actinobacteria 201174|Actinobacteria O Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family - - - ko:K07402 - - - - ko00000 - - - XdhC_C,XdhC_CoxI k141_21429_2 502025.Hoch_2002 5.62e-21 90.5 COG1319@1|root,COG1319@2|Bacteria,1PG5C@1224|Proteobacteria,43EJH@68525|delta/epsilon subdivisions,2X9UI@28221|Deltaproteobacteria,2Z2GS@29|Myxococcales 28221|Deltaproteobacteria C CO dehydrogenase flavoprotein C-terminal domain - - 1.2.5.3 ko:K03519 - - R11168 RC02800 ko00000,ko01000 - - - CO_deh_flav_C,FAD_binding_5 k141_3596_1 880073.Calab_0214 1.46e-86 281.0 COG0653@1|root,COG0653@2|Bacteria,2NNRK@2323|unclassified Bacteria 2|Bacteria U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW k141_17847_1 218284.CCDN010000006_gene3624 5.76e-115 341.0 COG1215@1|root,COG1215@2|Bacteria,1TR2P@1239|Firmicutes,4HAQN@91061|Bacilli,1ZCR1@1386|Bacillus 91061|Bacilli M Glycosyl transferase family group 2 icaA - - - - - - - - - - - Chitin_synth_2,Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_2 k141_18052_1 1348635.BBJY01000001_gene2394 4.1e-242 684.0 COG3119@1|root,COG3119@2|Bacteria,1MV92@1224|Proteobacteria,1RPDE@1236|Gammaproteobacteria,1XWJ5@135623|Vibrionales 135623|Vibrionales P Sulfatase - - 3.1.6.1 ko:K01130 ko00140,ko00600,map00140,map00600 - R03980,R04856 RC00128,RC00231 ko00000,ko00001,ko01000 - - - Sulfatase k141_12037_1 218284.CCDN010000009_gene4319 1.48e-174 497.0 COG1757@1|root,COG1757@2|Bacteria,1TQPI@1239|Firmicutes,4HBSV@91061|Bacilli,1ZDY2@1386|Bacillus 91061|Bacilli C antiporter nhaC_1 - - - - - - - - - - - Na_H_antiporter k141_36973_2 218284.CCDN010000002_gene2896 2.53e-71 218.0 2B4RH@1|root,31XHV@2|Bacteria,1V7MG@1239|Firmicutes,4HJAR@91061|Bacilli,1ZHAG@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - DUF2269 k141_36973_3 1134413.ANNK01000144_gene3842 3.39e-58 182.0 COG2411@1|root,COG2411@2|Bacteria,1V6QX@1239|Firmicutes,4HIQQ@91061|Bacilli,1ZH4F@1386|Bacillus 91061|Bacilli S ASCH - - - - - - - - - - - - ASCH k141_26355_1 1235457.C404_25915 3.39e-10 62.8 COG0672@1|root,COG2010@1|root,COG0672@2|Bacteria,COG2010@2|Bacteria,1MXHM@1224|Proteobacteria,2VIUK@28216|Betaproteobacteria,1KD18@119060|Burkholderiaceae 28216|Betaproteobacteria C Iron permease FTR1 family - - - ko:K07243 - - - - ko00000,ko02000 2.A.108.1,2.A.108.2 - - Cytochrome_CBB3,FTR1 k141_26355_2 991.IW20_05980 4.29e-48 172.0 COG0620@1|root,COG0620@2|Bacteria,4NF5S@976|Bacteroidetes,1HY90@117743|Flavobacteriia,2NUU6@237|Flavobacterium 976|Bacteroidetes E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation metE - 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_1,Meth_synt_2 k141_35782_2 218284.CCDN010000002_gene2661 7.07e-69 209.0 COG0640@1|root,COG0640@2|Bacteria,1VEER@1239|Firmicutes,4HM9M@91061|Bacilli,1ZHC7@1386|Bacillus 91061|Bacilli K transcriptional arsR GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - ko:K03892,ko:K22043 - - - - ko00000,ko03000 - - - HTH_5 k141_10815_1 1453501.JELR01000002_gene548 3.12e-25 99.4 2E6EA@1|root,3311R@2|Bacteria,1PFMW@1224|Proteobacteria,1SIKE@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Outer membrane protein beta-barrel domain - - - - - - - - - - - - OMP_b-brl k141_18053_1 1294265.JCM21738_2407 2.55e-163 461.0 COG0730@1|root,COG0730@2|Bacteria,1TPMA@1239|Firmicutes,4HCYJ@91061|Bacilli,1ZAPI@1386|Bacillus 91061|Bacilli S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE k141_12039_1 1453501.JELR01000002_gene478 4.81e-16 77.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MV8W@1224|Proteobacteria,1RSN6@1236|Gammaproteobacteria,4662Q@72275|Alteromonadaceae 1236|Gammaproteobacteria P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec k141_35783_1 574376.BAMA_23030 2.24e-36 134.0 COG0591@1|root,COG0591@2|Bacteria,1TPVE@1239|Firmicutes,4ITH8@91061|Bacilli 91061|Bacilli E Sodium:solute symporter family - - - - - - - - - - - - SSF k141_35783_2 1246484.D479_00770 4.37e-09 57.0 COG4468@1|root,COG4468@2|Bacteria,1TPBN@1239|Firmicutes,4HAYJ@91061|Bacilli,3NDSW@45667|Halobacillus 91061|Bacilli G Galactose-1-phosphate uridyl transferase, C-terminal domain galT - 2.7.7.12 ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 M00362,M00554,M00632 R00955 RC00002 ko00000,ko00001,ko00002,ko01000 - - - GalP_UDP_tr_C,GalP_UDP_transf k141_2566_1 861299.J421_3398 1.68e-67 215.0 COG1077@1|root,COG1077@2|Bacteria,1ZT9B@142182|Gemmatimonadetes 142182|Gemmatimonadetes D Hsp70 protein - - - ko:K03569 - - - - ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 - - MreB_Mbl k141_1298_1 1144312.PMI09_03741 3.93e-104 318.0 COG5361@1|root,COG5361@2|Bacteria,1NX2A@1224|Proteobacteria,2TTBA@28211|Alphaproteobacteria,4BAZE@82115|Rhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF1254) - - - - - - - - - - - - DUF1214,DUF1254 k141_34649_1 1116375.VEJY3_06775 1.37e-45 150.0 COG2059@1|root,COG2059@2|Bacteria,1NMSJ@1224|Proteobacteria,1SMRJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria P overlaps another CDS with the same product name - - - ko:K07240 - - - - ko00000,ko02000 2.A.51.1 - - Chromate_transp k141_34649_2 1116375.VEJY3_06770 4.91e-128 365.0 COG2059@1|root,COG2059@2|Bacteria,1NFD5@1224|Proteobacteria,1SF63@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Chromate transporter - - - ko:K07240 - - - - ko00000,ko02000 2.A.51.1 - - Chromate_transp k141_34649_3 1116375.VEJY3_06765 9.4e-165 466.0 2DBB6@1|root,2Z85M@2|Bacteria,1QMDX@1224|Proteobacteria,1RZPX@1236|Gammaproteobacteria,1XW23@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_34649_4 1116375.VEJY3_06760 1.1e-242 671.0 COG0624@1|root,COG0624@2|Bacteria,1MVUX@1224|Proteobacteria,1RPPD@1236|Gammaproteobacteria,1XV99@135623|Vibrionales 135623|Vibrionales E Peptidase family M20/M25/M40 - - 3.5.3.9 ko:K02083 ko00230,ko01120,map00230,map01120 - R02423 RC00064 ko00000,ko00001,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 k141_36974_1 42565.FP66_01125 2.8e-47 156.0 COG1280@1|root,COG1280@2|Bacteria,1RDPB@1224|Proteobacteria,1S5JJ@1236|Gammaproteobacteria,1XJSZ@135619|Oceanospirillales 135619|Oceanospirillales E Lysine exporter protein (LysE - - - - - - - - - - - - LysE k141_227_1 218284.CCDN010000001_gene1059 2.15e-153 433.0 COG1187@1|root,COG1187@2|Bacteria,1TP68@1239|Firmicutes,4H9MU@91061|Bacilli,1ZBNQ@1386|Bacillus 91061|Bacilli J Belongs to the pseudouridine synthase RsuA family rluB GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.22 ko:K06178 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 k141_9654_2 1385514.N782_19800 2.49e-47 158.0 COG1388@1|root,COG2340@1|root,COG1388@2|Bacteria,COG2340@2|Bacteria,1V6GZ@1239|Firmicutes,4HDFU@91061|Bacilli,2Y9VR@289201|Pontibacillus 91061|Bacilli M Cysteine-rich secretory protein family - - - - - - - - - - - - CAP,LysM k141_27469_1 665959.HMPREF1013_00381 1.07e-114 335.0 COG0223@1|root,COG0223@2|Bacteria,1TQ32@1239|Firmicutes,4HART@91061|Bacilli,1ZBSP@1386|Bacillus 91061|Bacilli J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus fmt GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 ko:K00604 ko00670,ko00970,map00670,map00970 - R03940 RC00026,RC00165 ko00000,ko00001,ko01000 - - iSB619.SA_RS06010 Formyl_trans_C,Formyl_trans_N k141_26356_1 1042377.AFPJ01000034_gene2356 1.38e-49 159.0 COG0792@1|root,COG0792@2|Bacteria,1N6VN@1224|Proteobacteria,1SC8A@1236|Gammaproteobacteria,468BF@72275|Alteromonadaceae 1236|Gammaproteobacteria L Belongs to the UPF0102 family yraN - - ko:K07460 - - - - ko00000 - - - UPF0102 k141_26356_2 1453501.JELR01000001_gene3057 1.2e-40 148.0 COG3107@1|root,COG3107@2|Bacteria,1MUHR@1224|Proteobacteria,1RXX4@1236|Gammaproteobacteria,465I7@72275|Alteromonadaceae 1236|Gammaproteobacteria M (Lipo)protein lpoA GO:0000270,GO:0003674,GO:0005575,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009279,GO:0009987,GO:0016020,GO:0019867,GO:0030203,GO:0030234,GO:0030312,GO:0030313,GO:0031241,GO:0031975,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044425,GO:0044462,GO:0044464,GO:0050790,GO:0065007,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0098552,GO:0098772,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 - ko:K07121 - - - - ko00000 - - - LppC k141_31106_1 441769.ABFU01000058_gene766 3.28e-86 265.0 COG4214@1|root,COG4214@2|Bacteria,1VU1F@1239|Firmicutes,4HBDM@91061|Bacilli,1ZQAE@1386|Bacillus 91061|Bacilli G Belongs to the binding-protein-dependent transport system permease family - - - ko:K10544,ko:K10547 ko02010,map02010 M00215,M00216 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.4,3.A.1.2.5 - - BPD_transp_2 k141_7297_1 498211.CJA_1140 1.67e-136 418.0 COG1472@1|root,COG2755@1|root,COG1472@2|Bacteria,COG2755@2|Bacteria,1MVIV@1224|Proteobacteria,1RMA0@1236|Gammaproteobacteria,1FIIP@10|Cellvibrio 1236|Gammaproteobacteria EG Glycosyl hydrolase family 3 C-terminal domain - - 3.2.1.21 ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 - R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - GH3 - CBM_6,Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C,Lipase_GDSL_2 k141_12040_1 1131730.BAVI_03814 3.25e-62 208.0 COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TSKR@1239|Firmicutes,4H9R5@91061|Bacilli,1ZDUE@1386|Bacillus 91061|Bacilli T COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain - - - ko:K07720 ko02020,map02020 M00519 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_18,HTH_AraC,Response_reg k141_2567_1 666686.B1NLA3E_06185 1.01e-70 216.0 COG1799@1|root,COG1799@2|Bacteria,1VER3@1239|Firmicutes,4HKIC@91061|Bacilli,1ZGE0@1386|Bacillus 91061|Bacilli D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA sepF GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0022402,GO:0022607,GO:0032506,GO:0042802,GO:0044085,GO:0051301,GO:0071840,GO:0090529 - ko:K09772 - - - - ko00000,ko03036 - - - SepF k141_28740_1 44251.PDUR_00085 8.41e-09 57.4 COG0125@1|root,COG0125@2|Bacteria,1V1HE@1239|Firmicutes,4HGWR@91061|Bacilli,26R3Y@186822|Paenibacillaceae 91061|Bacilli F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis tmk GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 ko:K00943 ko00240,ko01100,map00240,map01100 M00053 R02094,R02098 RC00002 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS02535 Thymidylate_kin k141_19152_1 1219076.N646_3510 0.0 927.0 COG3325@1|root,COG3979@1|root,COG3325@2|Bacteria,COG3979@2|Bacteria,1MWAR@1224|Proteobacteria,1RPNS@1236|Gammaproteobacteria,1XT0T@135623|Vibrionales 135623|Vibrionales G COG3325 Chitinase chiA - 3.2.1.14 ko:K01183 ko00520,ko01100,map00520,map01100 - R01206,R02334 RC00467 ko00000,ko00001,ko01000 - GH18 - CBM_5_12,ChitinaseA_N,Glyco_hydro_18,REJ k141_3760_1 349521.HCH_03674 5.93e-148 443.0 COG4412@1|root,COG4412@2|Bacteria,1P5IH@1224|Proteobacteria,1RPYC@1236|Gammaproteobacteria 1236|Gammaproteobacteria O peptidase M6 immune inhibitor A - - - ko:K09607 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M6 k141_9655_1 218284.CCDN010000001_gene25 2.19e-92 275.0 COG0571@1|root,COG0571@2|Bacteria,1TPGC@1239|Firmicutes,4HAWU@91061|Bacilli,1ZAPM@1386|Bacillus 91061|Bacilli J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism rnc GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 ko:K03685 ko03008,ko05205,map03008,map05205 - - - ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 - - - Ribonucleas_3_3,dsrm k141_7298_1 1128912.GMES_2109 2.18e-41 149.0 COG3203@1|root,COG3203@2|Bacteria,1QV46@1224|Proteobacteria,1T27N@1236|Gammaproteobacteria,46DE5@72275|Alteromonadaceae 1236|Gammaproteobacteria M Alginate export - - - - - - - - - - - - Alginate_exp k141_12041_1 1453501.JELR01000001_gene2734 2.9e-15 71.2 COG0789@1|root,COG0789@2|Bacteria,1N0AR@1224|Proteobacteria,1SBDH@1236|Gammaproteobacteria,4695G@72275|Alteromonadaceae 1236|Gammaproteobacteria K MerR HTH family regulatory protein cbpM - - ko:K18997 - - - - ko00000,ko03036 - - - MerR_2 k141_12041_2 1042377.AFPJ01000036_gene1164 1.05e-80 248.0 COG0484@1|root,COG0484@2|Bacteria,1MUZ4@1224|Proteobacteria,1RP09@1236|Gammaproteobacteria,4668N@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG2214 DnaJ-class molecular chaperone cbpA GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0097159,GO:1901363 - ko:K05516 - - - - ko00000,ko03036,ko03110 - - - DnaJ,DnaJ_C k141_229_1 1453501.JELR01000001_gene2960 8.3e-84 263.0 COG1030@1|root,COG1030@2|Bacteria,1MUJN@1224|Proteobacteria,1RN3U@1236|Gammaproteobacteria,465X3@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG1030 Membrane-bound serine protease (ClpP class) nfeD - - ko:K07403 - - - - ko00000 - - - NfeD k141_20324_1 498211.CJA_2709 4.53e-47 171.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MV8W@1224|Proteobacteria,1RMQA@1236|Gammaproteobacteria,1FH60@10|Cellvibrio 1236|Gammaproteobacteria P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec k141_3761_1 29495.EA26_14005 2.84e-112 327.0 COG0583@1|root,COG0583@2|Bacteria,1NQJW@1224|Proteobacteria,1SM2Q@1236|Gammaproteobacteria,1XWEM@135623|Vibrionales 135623|Vibrionales K Bacterial regulatory helix-turn-helix protein, lysR family - - - - - - - - - - - - HTH_1,LysR_substrate k141_7299_1 1121405.dsmv_0535 9.97e-73 243.0 COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,42KZE@68525|delta/epsilon subdivisions,2WIWK@28221|Deltaproteobacteria,2MI9Z@213118|Desulfobacterales 28221|Deltaproteobacteria CP Domain of unknown function (DUF4040) mrpA - - ko:K05559,ko:K05565 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - DUF4040,MnhB,Proton_antipo_M,Proton_antipo_N k141_31117_1 674977.VMC_02520 2.41e-37 129.0 COG3078@1|root,COG3078@2|Bacteria,1N8HM@1224|Proteobacteria,1SDUG@1236|Gammaproteobacteria,1XWXD@135623|Vibrionales 135623|Vibrionales S A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis yihI - - ko:K09894 - - - - ko00000 - - - YihI k141_31117_2 1116375.VEJY3_00505 4.2e-156 437.0 COG4106@1|root,COG4106@2|Bacteria,1QUFH@1224|Proteobacteria,1T1X5@1236|Gammaproteobacteria,1XTG8@135623|Vibrionales 135623|Vibrionales S 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1, 4-benzoquinol methylase - - - - - - - - - - - - Methyltransf_23 k141_31117_3 1116375.VEJY3_00500 4.35e-141 399.0 COG2863@1|root,COG2863@2|Bacteria,1N2NB@1224|Proteobacteria,1RZFP@1236|Gammaproteobacteria,1XVQC@135623|Vibrionales 135623|Vibrionales C COG2863 Cytochrome c553 cc4 - - - - - - - - - - - Cytochrom_C k141_31117_4 223926.28805091 9.72e-147 414.0 COG0218@1|root,COG0218@2|Bacteria,1MY3Z@1224|Proteobacteria,1RNJP@1236|Gammaproteobacteria,1XTW5@135623|Vibrionales 135623|Vibrionales D Necessary for normal cell division and for the maintenance of normal septation engB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K03978 - - - - ko00000,ko03036 - - - MMR_HSR1 k141_31117_5 223926.28809662 3.19e-59 186.0 COG3266@1|root,COG3266@2|Bacteria,1QK5V@1224|Proteobacteria,1TI92@1236|Gammaproteobacteria,1XYP2@135623|Vibrionales 135623|Vibrionales S Sporulation related domain - - - - - - - - - - - - SPOR k141_31117_6 223926.28805089 0.0 1310.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,1XUAZ@135623|Vibrionales 135623|Vibrionales L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k141_35799_1 218284.CCDN010000001_gene1280 9.48e-87 265.0 COG3393@1|root,COG3393@2|Bacteria,1V1XP@1239|Firmicutes,4HG3K@91061|Bacilli,1ZR7Q@1386|Bacillus 91061|Bacilli S FR47-like protein - - - ko:K06976 - - - - ko00000 - - - Acetyltransf_1,FR47 k141_8529_1 935837.JAEK01000007_gene3282 1.43e-110 332.0 COG0659@1|root,COG0659@2|Bacteria,1TPI4@1239|Firmicutes,4H9V4@91061|Bacilli,1ZCKC@1386|Bacillus 91061|Bacilli P COG0659 Sulfate permease and related transporters (MFS superfamily) ybaR - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - STAS,Sulfate_transp k141_12064_1 218284.CCDN010000002_gene2270 1.52e-201 567.0 COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,4HA6M@91061|Bacilli,1ZD4Q@1386|Bacillus 91061|Bacilli J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family rumA_1 - 2.1.1.190,2.1.1.35 ko:K00557,ko:K03215 - - - - ko00000,ko01000,ko03009,ko03016 - - - TRAM,tRNA_U5-meth_tr k141_33436_1 218284.CCDN010000005_gene3268 1.02e-124 382.0 COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HACY@91061|Bacilli,1ZB8K@1386|Bacillus 91061|Bacilli O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE clpB GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564 - ko:K03695 ko04213,map04213 - - - ko00000,ko00001,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N k141_15672_1 42565.FP66_05900 4.71e-60 185.0 COG2154@1|root,COG2154@2|Bacteria,1RH99@1224|Proteobacteria,1S5YX@1236|Gammaproteobacteria,1XKHH@135619|Oceanospirillales 135619|Oceanospirillales H pterin-4-alpha-carbinolamine dehydratase phhB - 4.2.1.96 ko:K01724 ko00790,map00790 - R04734 RC01208 ko00000,ko00001,ko01000,ko04147 - - - Pterin_4a k141_15672_2 42565.FP66_05905 9.9e-54 178.0 COG1448@1|root,COG1448@2|Bacteria,1MUT0@1224|Proteobacteria,1RN02@1236|Gammaproteobacteria,1XH9R@135619|Oceanospirillales 135619|Oceanospirillales E Aminotransferase - - 2.6.1.1,2.6.1.57 ko:K00813,ko:K00832 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 M00024,M00025,M00034,M00040 R00355,R00694,R00734,R00896,R01731,R02433,R02619,R05052,R07396,R10845 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k141_253_1 935836.JAEL01000029_gene3574 7.3e-29 116.0 COG0075@1|root,COG3916@1|root,COG0075@2|Bacteria,COG3916@2|Bacteria,1TR3I@1239|Firmicutes,4HA6W@91061|Bacilli,1ZAT2@1386|Bacillus 91061|Bacilli E Aminotransferase class-V - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10,Acetyltransf_5,Acetyltransf_9,Aminotran_5 k141_253_2 218284.CCDN010000001_gene1735 3.09e-72 236.0 COG1368@1|root,COG1368@2|Bacteria,1TRMA@1239|Firmicutes,4HFA5@91061|Bacilli,1ZDG2@1386|Bacillus 91061|Bacilli M Sulfatase - - - - - - - - - - - - Sulfatase k141_32217_1 1453501.JELR01000001_gene3083 8.24e-106 308.0 COG3117@1|root,COG3117@2|Bacteria,1NGCC@1224|Proteobacteria,1SGDP@1236|Gammaproteobacteria,468M6@72275|Alteromonadaceae 1236|Gammaproteobacteria S Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA lptC - - ko:K11719 - - - - ko00000,ko02000 1.B.42.1 - - LptC k141_7317_1 1453501.JELR01000001_gene2856 6e-230 661.0 COG1472@1|root,COG1472@2|Bacteria,1MVIV@1224|Proteobacteria,1RMA0@1236|Gammaproteobacteria,465BV@72275|Alteromonadaceae 1236|Gammaproteobacteria G Family 3 - - 3.2.1.21 ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 - R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - GH3 - Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C,Lipase_GDSL_2 k141_7317_2 73044.JNXP01000012_gene3799 3.34e-166 505.0 COG1472@1|root,COG1472@2|Bacteria,2GJ5H@201174|Actinobacteria 201174|Actinobacteria G hydrolase, family 3 - - 3.2.1.21 ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 - R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - GH3 - CBM_11,Calx-beta,Glyco_hydro_3,Glyco_hydro_3_C k141_27493_1 997296.PB1_03145 6.94e-98 315.0 COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,4HA3G@91061|Bacilli,1ZAVY@1386|Bacillus 91061|Bacilli T Diguanylate cyclase - - - - - - - - - - - - EAL,FIST,FIST_C,GAF_2,GGDEF,PAS,PAS_4,PAS_9,dCache_1 k141_12065_1 218284.CCDN010000009_gene4318 5.29e-92 276.0 COG1028@1|root,COG1028@2|Bacteria,1V1Z9@1239|Firmicutes,4HCPI@91061|Bacilli,1ZFQF@1386|Bacillus 91061|Bacilli IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) yueD - 1.1.1.320 ko:K16216 - - - - ko00000,ko01000 - - - adh_short k141_23923_1 218284.CCDN010000006_gene3578 4.43e-156 444.0 COG1834@1|root,COG1834@2|Bacteria,1UYBH@1239|Firmicutes,4HDEA@91061|Bacilli,1ZHNP@1386|Bacillus 91061|Bacilli E Amidinotransferase - - - - - - - - - - - - Amidinotransf k141_28765_1 1078085.HMPREF1210_02866 1.98e-26 115.0 COG1404@1|root,COG1404@2|Bacteria,1TPH1@1239|Firmicutes,4HBQH@91061|Bacilli 91061|Bacilli O Belongs to the peptidase S8 family prtS - 3.4.21.110,3.4.21.96 ko:K01361,ko:K08652 - - - - ko00000,ko01000,ko01002,ko03110 - - - FIVAR,Gram_pos_anchor,Inhibitor_I9,PA,Peptidase_S8,SLH,YSIRK_signal,fn3_5 k141_22759_1 1042377.AFPJ01000007_gene1864 2.84e-27 106.0 COG0665@1|root,COG0665@2|Bacteria,1RH7N@1224|Proteobacteria,1S9ZE@1236|Gammaproteobacteria,467V9@72275|Alteromonadaceae 1236|Gammaproteobacteria E tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity - - - - - - - - - - - - - k141_21614_1 1294265.JCM21738_4601 1.99e-10 58.9 COG3880@1|root,COG3880@2|Bacteria,1V6YM@1239|Firmicutes,4HH4R@91061|Bacilli,1ZG9T@1386|Bacillus 91061|Bacilli S protein with conserved CXXC pairs mcsA GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 - ko:K19411 - - - - ko00000 - - - UVR k141_21614_2 1307436.PBF_20493 3.18e-204 571.0 COG3869@1|root,COG3869@2|Bacteria,1TPBA@1239|Firmicutes,4HC6U@91061|Bacilli,1ZBJU@1386|Bacillus 91061|Bacilli E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity mcsB GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 ko:K19405 - - R11090 RC00002,RC00203 ko00000,ko01000 - - - ATP-gua_Ptrans k141_3780_1 1279017.AQYJ01000027_gene1994 5.68e-84 250.0 COG0824@1|root,COG0824@2|Bacteria,1RI3X@1224|Proteobacteria,1SAHQ@1236|Gammaproteobacteria,46DIX@72275|Alteromonadaceae 1236|Gammaproteobacteria S Thioesterase superfamily - - - ko:K07107 - - - - ko00000,ko01000 - - - 4HBT,4HBT_2,Acyl-ACP_TE k141_12066_1 1453501.JELR01000002_gene1033 2.39e-06 48.1 COG0189@1|root,COG0189@2|Bacteria,1MX5X@1224|Proteobacteria,1RNXP@1236|Gammaproteobacteria,464RX@72275|Alteromonadaceae 1236|Gammaproteobacteria HJ Glutathione synthase ribosomal protein S6 modification enzyme (Glutaminyl transferase) - - - - - - - - - - - - Dala_Dala_lig_C,RLAN,RimK k141_10830_1 1042377.AFPJ01000014_gene1660 7.36e-113 340.0 28K8N@1|root,2Z9WC@2|Bacteria,1R5V8@1224|Proteobacteria,1S3I5@1236|Gammaproteobacteria,466GB@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF3549) - - - - - - - - - - - - DUF3549 k141_10830_2 1279017.AQYJ01000023_gene3113 6.65e-81 256.0 COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,1RNIT@1236|Gammaproteobacteria,464TD@72275|Alteromonadaceae 1236|Gammaproteobacteria G Belongs to the GPI family pgi - 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 - - iJN746.PP_1808 PGI k141_6203_1 1279017.AQYJ01000029_gene3833 7.24e-119 345.0 COG2360@1|root,COG2360@2|Bacteria,1R9W8@1224|Proteobacteria,1S1ZB@1236|Gammaproteobacteria,466EF@72275|Alteromonadaceae 1236|Gammaproteobacteria O Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine aat GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.3.2.6 ko:K00684 - - R03813,R11443,R11444 RC00055,RC00064 ko00000,ko01000 - - - Leu_Phe_trans k141_28766_1 379066.GAU_1590 5.85e-58 191.0 COG0673@1|root,COG0673@2|Bacteria,1ZTES@142182|Gemmatimonadetes 142182|Gemmatimonadetes S Oxidoreductase family, NAD-binding Rossmann fold - - - - - - - - - - - - GFO_IDH_MocA k141_33438_1 1492922.GY26_04730 3.21e-96 288.0 COG4128@1|root,COG4128@2|Bacteria,1RCT1@1224|Proteobacteria 1224|Proteobacteria S Zonular occludens toxin (Zot) - - - - - - - - - - - - Zot k141_13280_1 1042377.AFPJ01000011_gene421 1.7e-107 318.0 COG1683@1|root,COG3272@1|root,COG1683@2|Bacteria,COG3272@2|Bacteria,1MXYZ@1224|Proteobacteria,1RNMF@1236|Gammaproteobacteria,464ZQ@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF1722) ybgA - - - - - - - - - - - DUF1722,DUF523 k141_7318_1 218284.CCDN010000008_gene4246 2.09e-207 584.0 COG0365@1|root,COG0365@2|Bacteria,1TQTI@1239|Firmicutes,4H9PN@91061|Bacilli,1ZBDX@1386|Bacillus 91061|Bacilli I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases acsA - 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 - - - AMP-binding,AMP-binding_C k141_29869_1 1243664.CAVL020000055_gene2571 8.61e-26 104.0 COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TPJ8@1239|Firmicutes,4HA8X@91061|Bacilli,1ZAZ3@1386|Bacillus 91061|Bacilli G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific nagE - 2.7.1.193,2.7.1.199 ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 M00267,M00809 R02738,R05199 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.13,4.A.1.1.14,4.A.1.1.15,4.A.1.1.2,4.A.1.1.5,4.A.1.1.7,4.A.1.1.9 - iSB619.SA_RS08720 PTS_EIIA_1,PTS_EIIB,PTS_EIIC k141_20336_1 218284.CCDN010000011_gene4427 0.0 1194.0 COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TPJ8@1239|Firmicutes,4HA8X@91061|Bacilli,1ZC48@1386|Bacillus 91061|Bacilli G phosphotransferase system ptsG GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.1.199 ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 M00809 R02738 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.13,4.A.1.1.14,4.A.1.1.9 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC k141_1330_2 1479235.KK366039_gene2987 7.2e-223 618.0 COG1304@1|root,COG1304@2|Bacteria,1N6KI@1224|Proteobacteria,1RP1W@1236|Gammaproteobacteria,1XJ1Z@135619|Oceanospirillales 135619|Oceanospirillales C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) fni - - - - - - - - - - - FMN_dh k141_35801_1 218284.CCDN010000002_gene2811 3.13e-80 238.0 COG3832@1|root,COG3832@2|Bacteria,1V7US@1239|Firmicutes,4HK0E@91061|Bacilli,1ZGHK@1386|Bacillus 91061|Bacilli S Activator of Hsp90 ATPase homolog 1-like protein yndB - - - - - - - - - - - AHSA1 k141_7319_1 1450694.BTS2_1087 3.53e-09 54.7 COG0346@1|root,COG0346@2|Bacteria,1VHQM@1239|Firmicutes,4HP61@91061|Bacilli,1ZHUW@1386|Bacillus 91061|Bacilli E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - 4.4.1.5 ko:K01759 ko00620,map00620 - R02530 RC00004,RC00740 ko00000,ko00001,ko01000 - - - Glyoxalase,Glyoxalase_4 k141_7319_2 218284.CCDN010000007_gene3902 8.95e-37 129.0 COG2364@1|root,COG2364@2|Bacteria,1V47R@1239|Firmicutes,4HGYQ@91061|Bacilli,1ZG36@1386|Bacillus 91061|Bacilli S membrane yczE GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008897,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016780,GO:0019752,GO:0019878,GO:0043436,GO:0043900,GO:0043902,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0065007,GO:0071704,GO:1900190,GO:1900192,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - ko:K07149 - - - - ko00000 - - - YitT_membrane k141_31120_1 218284.CCDN010000001_gene469 7.55e-83 251.0 COG4587@1|root,COG4587@2|Bacteria,1VDUN@1239|Firmicutes,4HE8R@91061|Bacilli,1ZJIC@1386|Bacillus 91061|Bacilli S ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_6 k141_31120_2 218284.CCDN010000001_gene468 2.78e-18 82.4 COG4586@1|root,COG4586@2|Bacteria,1TP1N@1239|Firmicutes,4H9NR@91061|Bacilli,1ZBGB@1386|Bacillus 91061|Bacilli S transport system, ATPase component - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_33439_1 1453501.JELR01000001_gene2929 9.88e-92 296.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,466AN@72275|Alteromonadaceae 1236|Gammaproteobacteria V AcrB/AcrD/AcrF family bepG - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran k141_27495_2 1294265.JCM21738_4339 3.55e-128 367.0 COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,4HAPT@91061|Bacilli,1ZB6N@1386|Bacillus 91061|Bacilli G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) tpiA GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01015 RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 - - - TIM k141_15673_1 1504981.KO116_4831 3.55e-261 719.0 COG3328@1|root,COG3328@2|Bacteria,1QE3G@1224|Proteobacteria,1TBD7@1236|Gammaproteobacteria,1XQDQ@135619|Oceanospirillales 135619|Oceanospirillales L transposase activity - - - - - - - - - - - - - k141_28768_1 1042377.AFPJ01000029_gene526 2.17e-25 102.0 2DR2Y@1|root,339YA@2|Bacteria,1NHB7@1224|Proteobacteria,1SH0X@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF4124) - - - - - - - - - - - - DUF4124 k141_12069_1 1294265.JCM21738_574 7.83e-33 114.0 2EQSH@1|root,33ICC@2|Bacteria,1VN5W@1239|Firmicutes,4HRDG@91061|Bacilli,1ZIX3@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_21615_1 218284.CCDN010000002_gene2207 5.29e-184 516.0 COG1077@1|root,COG1077@2|Bacteria,1TP51@1239|Firmicutes,4HC52@91061|Bacilli,1ZCN2@1386|Bacillus 91061|Bacilli D Rod-share determining protein MreBH mreBH - - ko:K03569 - - - - ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 - - MreB_Mbl k141_25114_1 1453501.JELR01000002_gene753 1.36e-302 841.0 COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria,4658C@72275|Alteromonadaceae 1236|Gammaproteobacteria V COG1132 ABC-type multidrug transport system, ATPase and permease components draA - - ko:K06147,ko:K11085 ko02010,map02010 - - - ko00000,ko00001,ko01000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran k141_25114_3 626887.J057_15245 6.76e-41 139.0 2BY4C@1|root,32XUX@2|Bacteria,1N0C0@1224|Proteobacteria,1SAJV@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_28925_5 1116375.VEJY3_15856 1.8e-261 719.0 COG0786@1|root,COG0786@2|Bacteria,1MVBC@1224|Proteobacteria,1RP0S@1236|Gammaproteobacteria,1XUE5@135623|Vibrionales 135623|Vibrionales P Catalyzes the sodium-dependent transport of glutamate gltS - - ko:K03312 - - - - ko00000,ko02000 2.A.27 - - Glt_symporter k141_23042_1 1453501.JELR01000001_gene2062 2e-91 287.0 COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,1RNQ2@1236|Gammaproteobacteria,4640F@72275|Alteromonadaceae 1236|Gammaproteobacteria GM nucleoside-diphosphate sugar epimerases wbpM - - - - - - - - - - - CoA_binding_3,Polysacc_synt_2 k141_13565_1 1121439.dsat_1972 7.12e-35 134.0 COG2199@1|root,COG3706@2|Bacteria,1MXBG@1224|Proteobacteria,42NGW@68525|delta/epsilon subdivisions,2X6BI@28221|Deltaproteobacteria,2M8YS@213115|Desulfovibrionales 28221|Deltaproteobacteria T PFAM GGDEF domain containing protein, response regulator receiver - - - - - - - - - - - - GGDEF,Response_reg k141_18268_2 218284.CCDN010000006_gene3561 9.35e-32 110.0 2E3H2@1|root,32YFR@2|Bacteria,1VF0S@1239|Firmicutes,4HNTB@91061|Bacilli,1ZJ4H@1386|Bacillus 91061|Bacilli S Domain of Unknown Function (DUF1540) - - - - - - - - - - - - DUF1540 k141_14614_1 1279015.KB908460_gene2824 4.95e-102 313.0 COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,1RMFY@1236|Gammaproteobacteria,1Y3HM@135624|Aeromonadales 135624|Aeromonadales J thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence rpsA - - ko:K02945 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - S1 k141_26734_1 218284.CCDN010000001_gene1675 1.41e-123 363.0 COG3048@1|root,COG3048@2|Bacteria,1TPAH@1239|Firmicutes,4HANC@91061|Bacilli,1ZASU@1386|Bacillus 91061|Bacilli E Belongs to the serine threonine dehydratase family. DsdA subfamily dsdA GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008721,GO:0009987,GO:0016829,GO:0016840,GO:0016841,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564 4.3.1.18 ko:K01753 ko00260,map00260 - R00221 RC02600 ko00000,ko00001,ko01000 - - - PALP k141_12387_2 1453501.JELR01000002_gene1264 2.44e-73 221.0 COG0139@1|root,COG0139@2|Bacteria,1MW67@1224|Proteobacteria,1RMV4@1236|Gammaproteobacteria,4679A@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP hisI GO:0000105,GO:0003674,GO:0003824,GO:0004635,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.4.19,3.6.1.31 ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035,R04037 RC00002,RC01055 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_5014 PRA-CH,PRA-PH k141_6436_1 1116375.VEJY3_18941 0.0 1173.0 COG5001@1|root,COG5001@2|Bacteria,1PRV9@1224|Proteobacteria,1RZHM@1236|Gammaproteobacteria,1XSCI@135623|Vibrionales 135623|Vibrionales T COG2199 FOG GGDEF domain mbaA GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0023052,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007 3.1.4.52 ko:K20966 ko05111,map05111 - - - ko00000,ko00001,ko01000 - - - EAL,GGDEF k141_30005_1 698769.JFBD01000072_gene1842 3.95e-85 267.0 COG0591@1|root,COG0591@2|Bacteria,1U2RF@1239|Firmicutes,4IJK4@91061|Bacilli,4C68Z@84406|Virgibacillus 91061|Bacilli E Sodium:solute symporter family - - - ko:K03307 - - - - ko00000 2.A.21 - - SSF k141_5130_1 1294265.JCM21738_1888 1.33e-74 228.0 COG2382@1|root,COG2382@2|Bacteria,1UCAC@1239|Firmicutes,4HC02@91061|Bacilli,1ZBAQ@1386|Bacillus 91061|Bacilli P COG2382 Enterochelin esterase and related enzymes yjcH - - ko:K07214 - - - - ko00000 - - - Esterase k141_5130_2 1294265.JCM21738_1889 9.57e-24 94.0 COG1514@1|root,COG1514@2|Bacteria,1V2F3@1239|Firmicutes,4HG6P@91061|Bacilli,1ZG9R@1386|Bacillus 91061|Bacilli J Belongs to the 2H phosphoesterase superfamily. YjcG family yjcG - - - - - - - - - - - 2_5_RNA_ligase2 k141_9930_2 1116375.VEJY3_07300 9.7e-192 533.0 COG1176@1|root,COG1176@2|Bacteria,1MVGM@1224|Proteobacteria,1RNNZ@1236|Gammaproteobacteria,1XSQ9@135623|Vibrionales 135623|Vibrionales P Spermidine putrescine ABC transporter potB - - ko:K11071 ko02010,map02010 M00299 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 - - BPD_transp_1 k141_9930_3 1219076.N646_0577 2.09e-30 113.0 COG1177@1|root,COG1177@2|Bacteria,1MVC5@1224|Proteobacteria,1RQB7@1236|Gammaproteobacteria,1XT48@135623|Vibrionales 135623|Vibrionales P Spermidine putrescine ABC transporter potC - - ko:K11070 ko02010,map02010 M00299 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 - - BPD_transp_1 k141_37167_1 218284.CCDN010000001_gene382 6.4e-117 340.0 COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,4H9ZW@91061|Bacilli,1ZB08@1386|Bacillus 91061|Bacilli S COG0618 Exopolyphosphatase-related proteins nrnA - 3.1.13.3,3.1.3.7 ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 - R00188,R00508 RC00078 ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1 k141_11092_2 1453501.JELR01000005_gene1647 3.09e-60 188.0 COG0346@1|root,COG0346@2|Bacteria,1N1HF@1224|Proteobacteria,1SFPY@1236|Gammaproteobacteria 1236|Gammaproteobacteria E lactoylglutathione lyase activity - - - - - - - - - - - - - k141_11092_4 1279017.AQYJ01000028_gene2307 1.83e-35 131.0 COG2603@1|root,COG2603@2|Bacteria,1N4T5@1224|Proteobacteria,1RPFP@1236|Gammaproteobacteria,46469@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA selU GO:0001887,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016785,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043828,GO:0044237,GO:0044238,GO:0046483,GO:0070329,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 - ko:K06917 - - - - ko00000,ko01000,ko03016 - - - Rhodanese k141_494_1 247634.GPB2148_3348 7.79e-158 464.0 COG1629@1|root,COG4771@2|Bacteria,1MUNK@1224|Proteobacteria,1RN9S@1236|Gammaproteobacteria,1J59B@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_20532_1 1035191.HMPREF0185_00217 3.27e-26 108.0 COG1173@1|root,COG1173@2|Bacteria,1MW3R@1224|Proteobacteria,2VF93@28211|Alphaproteobacteria 28211|Alphaproteobacteria EP Binding-protein-dependent transport system inner membrane component - - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 k141_13567_1 218284.CCDN010000002_gene2045 5.56e-80 253.0 28HMX@1|root,2Z7WB@2|Bacteria,1TPJG@1239|Firmicutes,4HBRI@91061|Bacilli,1ZCDH@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_35961_1 1116375.VEJY3_00685 9.27e-167 468.0 COG0596@1|root,COG0596@2|Bacteria,1QUBR@1224|Proteobacteria,1RSF9@1236|Gammaproteobacteria,1XSHE@135623|Vibrionales 135623|Vibrionales S The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters bioH GO:0003674,GO:0003824,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016787,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.1.1.85 ko:K02170 ko00780,ko01100,map00780,map01100 M00572 R09725 RC00460,RC00461 ko00000,ko00001,ko00002,ko01000 - - - Abhydrolase_1 k141_35961_2 223926.28805131 3.27e-93 273.0 2APKV@1|root,31EQ4@2|Bacteria,1QJN4@1224|Proteobacteria,1THNR@1236|Gammaproteobacteria,1XWYE@135623|Vibrionales 135623|Vibrionales - - VV10861 - - - - - - - - - - - - k141_35961_3 674977.VMC_14030 0.0 1404.0 COG2183@1|root,COG2183@2|Bacteria,1MUA7@1224|Proteobacteria,1RMNH@1236|Gammaproteobacteria,1XTBQ@135623|Vibrionales 135623|Vibrionales K accessory protein yhgF - - ko:K06959 - - - - ko00000 - - - HHH_3,S1,Tex_N,Tex_YqgF k141_35961_4 1116375.VEJY3_00700 0.0 1022.0 COG4067@1|root,COG4067@2|Bacteria,1R9C1@1224|Proteobacteria,1S122@1236|Gammaproteobacteria,1XUBD@135623|Vibrionales 135623|Vibrionales O Putative ATP-dependant zinc protease - - - - - - - - - - - - Zn_protease k141_35961_5 223926.28805134 3.35e-110 317.0 COG0782@1|root,COG0782@2|Bacteria,1RAP0@1224|Proteobacteria,1S40Q@1236|Gammaproteobacteria,1XV4E@135623|Vibrionales 135623|Vibrionales K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length greB GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - ko:K04760 - - - - ko00000,ko03021 - - - GreA_GreB,GreA_GreB_N k141_35961_6 223926.28805136 4.3e-167 467.0 COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,1RPKN@1236|Gammaproteobacteria,1XUWU@135623|Vibrionales 135623|Vibrionales K COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain ompR - - ko:K07659 ko02020,ko02026,map02020,map02026 M00445,M00742,M00743 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C k141_35961_7 1116375.VEJY3_00720 3.4e-243 674.0 COG0642@1|root,COG2205@2|Bacteria,1MUAK@1224|Proteobacteria,1RPP2@1236|Gammaproteobacteria,1XSMP@135623|Vibrionales 135623|Vibrionales T Osmolarity sensor protein envZ - 2.7.13.3 ko:K07638 ko02020,ko02026,map02020,map02026 M00445,M00742,M00743 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA k141_7473_1 1177154.Y5S_01706 3.37e-64 222.0 COG1361@1|root,COG1361@2|Bacteria,1QVSF@1224|Proteobacteria 1224|Proteobacteria M domain protein - - - - - - - - - - - - CARDB,DUF11,OmpA_membrane k141_19400_2 1042377.AFPJ01000028_gene2177 2.47e-43 142.0 COG1598@1|root,COG1598@2|Bacteria,1N8WR@1224|Proteobacteria,1TBBZ@1236|Gammaproteobacteria,46C9A@72275|Alteromonadaceae 1236|Gammaproteobacteria S HicB_like antitoxin of bacterial toxin-antitoxin system - - - - - - - - - - - - HicB_lk_antitox k141_21790_1 218284.CCDN010000001_gene1885 3.07e-45 155.0 COG0130@1|root,COG0130@2|Bacteria,1TP9Y@1239|Firmicutes,4HA9X@91061|Bacilli,1ZBKE@1386|Bacillus 91061|Bacilli J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs truB GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 ko:K03177,ko:K03483 - - - - ko00000,ko01000,ko03000,ko03016 - - iSB619.SA_RS06305 TruB-C_2,TruB_C_2,TruB_N k141_21790_2 1295642.H839_05079 1.35e-10 61.6 COG0196@1|root,COG0196@2|Bacteria,1TPKS@1239|Firmicutes,4H9KE@91061|Bacilli,1WES7@129337|Geobacillus 91061|Bacilli H Belongs to the ribF family ribF - 2.7.1.26,2.7.7.2 ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS06310 FAD_syn,Flavokinase k141_1527_1 218284.CCDN010000001_gene58 9.32e-261 743.0 COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,4HAEY@91061|Bacilli,1ZCEM@1386|Bacillus 91061|Bacilli F Belongs to the CarB family carB GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS k141_11094_1 1123279.ATUS01000001_gene1232 1.48e-61 198.0 COG1957@1|root,COG1957@2|Bacteria,1QYX6@1224|Proteobacteria,1T3WB@1236|Gammaproteobacteria,1JC35@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria F Protein of unknown function, DUF547 - - - - - - - - - - - - DUF547 k141_18271_2 218284.CCDN010000001_gene944 1.51e-41 138.0 COG0607@1|root,COG0607@2|Bacteria,1VAI7@1239|Firmicutes,4HKCE@91061|Bacilli,1ZGZX@1386|Bacillus 91061|Bacilli P COG0607 Rhodanese-related sulfurtransferase yqhL - - - - - - - - - - - Rhodanese k141_33698_1 1279017.AQYJ01000025_gene568 2.19e-200 577.0 COG0642@1|root,COG0784@1|root,COG0642@2|Bacteria,COG0784@2|Bacteria,1R4TJ@1224|Proteobacteria,1RQKQ@1236|Gammaproteobacteria,4671J@72275|Alteromonadaceae 1236|Gammaproteobacteria T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,Response_reg k141_14615_4 1206557.I7KQW5_9CAUD 6.54e-06 46.6 4QAIU@10239|Viruses,4QUQC@35237|dsDNA viruses no RNA stage,4QPDE@28883|Caudovirales,4QKM7@10699|Siphoviridae 10699|Siphoviridae S HNH endonuclease - - - - - - - - - - - - - k141_32371_1 247633.GP2143_00277 1.03e-40 147.0 COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,1RMRD@1236|Gammaproteobacteria 1236|Gammaproteobacteria P antiporter yrbG - - ko:K07301 - - - - ko00000,ko02000 2.A.19.5 - - Na_Ca_ex k141_32371_2 1042377.AFPJ01000034_gene2333 6.33e-195 545.0 COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1MUXD@1224|Proteobacteria,1RMT9@1236|Gammaproteobacteria,464TG@72275|Alteromonadaceae 1236|Gammaproteobacteria M Arabinose 5-phosphate isomerase kdsD GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005996,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0019146,GO:0019294,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0046364,GO:0046394,GO:0046400,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 5.3.1.13 ko:K06041 ko00540,ko01100,map00540,map01100 M00063 R01530 RC00541 ko00000,ko00001,ko00002,ko01000,ko01005 - - iECH74115_1262.ECH74115_4519,iECSP_1301.ECSP_4172,iECs_1301.ECs4076,iPC815.YPO3577,iSFV_1184.SFV_3227,iSFxv_1172.SFxv_3550,iYL1228.KPN_03607,iZ_1308.Z4560 CBS,SIS k141_33716_1 1279017.AQYJ01000022_gene2691 3.64e-105 313.0 COG2207@1|root,COG2207@2|Bacteria,1MUEM@1224|Proteobacteria,1T1VS@1236|Gammaproteobacteria,467PV@72275|Alteromonadaceae 1236|Gammaproteobacteria K AraC-type transcriptional regulator N-terminus - - - - - - - - - - - - AraC_N,HTH_18 k141_33716_2 1089552.KI911559_gene2843 4.34e-17 76.6 2EJQP@1|root,33DFH@2|Bacteria,1NI6C@1224|Proteobacteria,2UMF9@28211|Alphaproteobacteria,2JY14@204441|Rhodospirillales 204441|Rhodospirillales P High potential iron-sulfur protein - - - - - - - - - - - - HIPIP k141_33716_3 1385513.N780_19910 3.18e-162 481.0 COG4412@1|root,COG4412@2|Bacteria,1TQYP@1239|Firmicutes,4HD82@91061|Bacilli,2YA1P@289201|Pontibacillus 91061|Bacilli S protease - - - ko:K09607 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M6 k141_24142_1 1294265.JCM21738_4831 1.24e-102 308.0 COG2986@1|root,COG2986@2|Bacteria,1TPCW@1239|Firmicutes,4H9YS@91061|Bacilli,1ZC8Z@1386|Bacillus 91061|Bacilli E Histidine ammonia-lyase hutH - 4.3.1.3 ko:K01745 ko00340,ko01100,map00340,map01100 M00045 R01168 RC00361 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU39350 Lyase_aromatic k141_18296_1 218284.CCDN010000002_gene2162 2.16e-118 350.0 COG5520@1|root,COG5520@2|Bacteria,1TS99@1239|Firmicutes,4HEUA@91061|Bacilli,1ZF3X@1386|Bacillus 91061|Bacilli M Belongs to the glycosyl hydrolase 30 family - - 3.2.1.45 ko:K01201 ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142 - R01498 RC00059,RC00451 ko00000,ko00001,ko01000 - GH30 - Glyco_hydro_30,Glyco_hydro_30C k141_20556_1 218284.CCDN010000001_gene1428 1.34e-188 524.0 COG1586@1|root,COG1586@2|Bacteria,1TQ7S@1239|Firmicutes,4HA9C@91061|Bacilli,1ZBP2@1386|Bacillus 91061|Bacilli E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine speD - 4.1.1.50 ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 M00034,M00133 R00178 RC00299 ko00000,ko00001,ko00002,ko01000 - - - AdoMet_dc k141_33719_1 1294265.JCM21738_333 5.14e-40 134.0 2EQVH@1|root,33IFA@2|Bacteria,1VKS4@1239|Firmicutes,4HS0N@91061|Bacilli,1ZJ67@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_33719_2 1294265.JCM21738_332 3.02e-49 169.0 COG1315@1|root,COG1315@2|Bacteria,1TR7W@1239|Firmicutes,4H9TJ@91061|Bacilli,1ZC1A@1386|Bacillus 91061|Bacilli L Flagellar Assembly Protein A - - - ko:K09749 - - - - ko00000 - - - FapA k141_12416_1 1034347.CAHJ01000017_gene3422 2.95e-49 177.0 COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,4HA3G@91061|Bacilli,1ZAVY@1386|Bacillus 91061|Bacilli T Diguanylate cyclase - - - - - - - - - - - - EAL,FIST,FIST_C,GAF_2,GGDEF,PAS,PAS_3,PAS_4,PAS_9,dCache_1 k141_9946_1 223926.28807301 0.0 1211.0 COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,1RP0K@1236|Gammaproteobacteria,1XTXD@135623|Vibrionales 135623|Vibrionales L COG0587 DNA polymerase III, alpha subunit dnaE GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon k141_9946_2 223926.28807300 1.59e-218 604.0 COG0825@1|root,COG0825@2|Bacteria,1MURN@1224|Proteobacteria,1RNN8@1236|Gammaproteobacteria,1XU3J@135623|Vibrionales 135623|Vibrionales I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA accA GO:0003674,GO:0003824,GO:0003989,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009317,GO:0009987,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0019752,GO:0032787,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576,GO:1902494 2.1.3.15,6.4.1.2 ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - ACCA k141_9946_3 1116375.VEJY3_11990 1.31e-254 705.0 COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,1RN14@1236|Gammaproteobacteria,1XTTB@135623|Vibrionales 135623|Vibrionales J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine tilS - 6.3.4.19 ko:K04075 - - R09597 RC02633,RC02634 ko00000,ko01000,ko03016 - - - ATP_bind_3,TilS,TilS_C k141_9946_4 1116375.VEJY3_11985 2.04e-56 176.0 COG2863@1|root,COG2863@2|Bacteria,1N7W9@1224|Proteobacteria,1S90Z@1236|Gammaproteobacteria,1XXSJ@135623|Vibrionales 135623|Vibrionales C COG2863 Cytochrome c553 - - - - - - - - - - - - Cytochrom_C k141_9946_5 1280001.BAOA01000081_gene2998 1.16e-71 216.0 COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,1S67I@1236|Gammaproteobacteria,1XXCB@135623|Vibrionales 135623|Vibrionales K Belongs to the P(II) protein family glnB - - ko:K04751 ko02020,map02020 - - - ko00000,ko00001 - - - P-II k141_9946_6 1116375.VEJY3_11975 1.98e-177 497.0 COG3021@1|root,COG3021@2|Bacteria,1MVPP@1224|Proteobacteria,1RMBH@1236|Gammaproteobacteria,1XTWA@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria - - - - - - - - - - - - Exo_endo_phos k141_9946_7 1219076.N646_1406 6.83e-154 433.0 29T5U@1|root,30ECJ@2|Bacteria,1RGM8@1224|Proteobacteria,1S46N@1236|Gammaproteobacteria,1XUUU@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF1282) VP2297 - - - - - - - - - - - DUF1282 k141_9946_8 1116375.VEJY3_11965 0.0 919.0 COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,1RMFZ@1236|Gammaproteobacteria,1XUFQ@135623|Vibrionales 135623|Vibrionales M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) mltD - - ko:K08307 - - - - ko00000,ko01000,ko01011 - - - LysM,SLT k141_9946_9 1116375.VEJY3_11960 1.01e-176 493.0 COG0491@1|root,COG0491@2|Bacteria,1MU8Q@1224|Proteobacteria,1S22I@1236|Gammaproteobacteria,1XTAM@135623|Vibrionales 135623|Vibrionales S Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid gloB GO:0003674,GO:0003824,GO:0004416,GO:0006518,GO:0006575,GO:0006749,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0034641,GO:0043603,GO:0044237,GO:0051186,GO:0071704,GO:1901564 3.1.2.6 ko:K01069 ko00620,map00620 - R01736 RC00004,RC00137 ko00000,ko00001,ko01000 - - - HAGH_C,Lactamase_B k141_9946_10 1116375.VEJY3_11955 6.89e-179 498.0 COG0500@1|root,COG2226@2|Bacteria,1QTWC@1224|Proteobacteria,1RS4G@1236|Gammaproteobacteria,1XTUC@135623|Vibrionales 135623|Vibrionales Q COG0500 SAM-dependent methyltransferases yafS - - - - - - - - - - - Methyltransf_11 k141_9946_11 1219076.N646_1402 9.04e-111 318.0 COG0328@1|root,COG0328@2|Bacteria,1RCZ1@1224|Proteobacteria,1S3YC@1236|Gammaproteobacteria,1XT8K@135623|Vibrionales 135623|Vibrionales L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhA GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03469 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_H k141_9946_12 223926.28807290 2.8e-168 470.0 COG0847@1|root,COG0847@2|Bacteria,1MV8Z@1224|Proteobacteria,1RNHQ@1236|Gammaproteobacteria,1XTSV@135623|Vibrionales 135623|Vibrionales L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease dnaQ - 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - RNase_T k141_9946_13 223926.28807289 1.19e-158 453.0 COG2304@1|root,COG2304@2|Bacteria,1MVJ2@1224|Proteobacteria,1RMUF@1236|Gammaproteobacteria,1XSUT@135623|Vibrionales 135623|Vibrionales S von willebrand factor, type A - - - - - - - - - - - - - k141_8785_1 1042377.AFPJ01000028_gene2297 0.0 984.0 COG1404@1|root,COG5640@1|root,COG1404@2|Bacteria,COG5640@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria,464PM@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG1404 Subtilisin-like serine proteases - GO:0005575,GO:0005576 - ko:K14645 ko02024,map02024 - - - ko00000,ko00001,ko01000,ko01002,ko03110 - - - PKD,PPC,P_proprotein,Peptidase_S8 k141_37188_1 426117.M446_3714 9.04e-94 283.0 COG0382@1|root,COG0382@2|Bacteria,1MVS1@1224|Proteobacteria,2TVKN@28211|Alphaproteobacteria,1JTGW@119045|Methylobacteriaceae 28211|Alphaproteobacteria H TIGRFAM bacteriochlorophyll chlorophyll synthetase bchG - 2.5.1.133,2.5.1.62 ko:K04040 ko00860,ko01100,ko01110,map00860,map01100,map01110 - R06284,R09067,R11514,R11517 RC00020 ko00000,ko00001,ko01000,ko01006 - - - UbiA k141_25398_1 935836.JAEL01000014_gene2016 1.32e-93 275.0 COG1225@1|root,COG1225@2|Bacteria,1V3N5@1239|Firmicutes,4HH7Z@91061|Bacilli,1ZFKU@1386|Bacillus 91061|Bacilli O Peroxiredoxin bcp - 1.11.1.15 ko:K03564 - - - - ko00000,ko01000 - - - AhpC-TSA k141_25398_2 218284.CCDN010000002_gene2949 6.69e-52 166.0 COG1226@1|root,32UM6@2|Bacteria,1VC22@1239|Firmicutes,4HMGA@91061|Bacilli,1ZJ2P@1386|Bacillus 91061|Bacilli P Ion transport - - - ko:K08713 - - - - ko00000,ko02000 1.A.1.29.1 - - Ion_trans_2 k141_13606_1 1279017.AQYJ01000027_gene1610 1.88e-163 468.0 COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,1RN6I@1236|Gammaproteobacteria,4654G@72275|Alteromonadaceae 1236|Gammaproteobacteria H Involved in the biosynthesis of porphyrin-containing compound yggW GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - - - - - - - - - - HemN_C,Radical_SAM k141_13606_2 1279017.AQYJ01000027_gene1609 2.14e-72 217.0 COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,1S5WR@1236|Gammaproteobacteria,467AS@72275|Alteromonadaceae 1236|Gammaproteobacteria O Belongs to the thioredoxin family trxA GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - ko:K03671 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - iECW_1372.ECW_m4079,iECs_1301.ECs4714,iEKO11_1354.EKO11_4576,iG2583_1286.G2583_4574,iSBO_1134.SBO_3791,iSDY_1059.SDY_3968,iSF_1195.SF3854,iSSON_1240.SSON_3952,iS_1188.S3905,iWFL_1372.ECW_m4079,iZ_1308.Z5291 Thioredoxin k141_13606_3 1453501.JELR01000002_gene976 1.19e-295 809.0 COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,1RP95@1236|Gammaproteobacteria,464AJ@72275|Alteromonadaceae 1236|Gammaproteobacteria K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template rho GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - ko:K03628 ko03018,map03018 - - - ko00000,ko00001,ko03019,ko03021 - - - ATP-synt_ab,Rho_N,Rho_RNA_bind k141_24144_1 1307436.PBF_06506 1.35e-102 314.0 COG0477@1|root,COG2814@2|Bacteria,1VSW8@1239|Firmicutes,4HUQC@91061|Bacilli,1ZAS8@1386|Bacillus 91061|Bacilli EGP the major facilitator superfamily bmr3 - - - - - - - - - - - MFS_1 k141_14631_1 311424.DhcVS_1112 1.62e-43 147.0 COG0454@1|root,COG0456@2|Bacteria,2GATN@200795|Chloroflexi,34DBC@301297|Dehalococcoidia 301297|Dehalococcoidia K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1 k141_1535_1 223926.28805772 1.05e-84 260.0 COG1344@1|root,COG1344@2|Bacteria,1PJUJ@1224|Proteobacteria,1RPNR@1236|Gammaproteobacteria,1XTKN@135623|Vibrionales 135623|Vibrionales N COG1344 Flagellin and related hook-associated proteins flgL - - ko:K02397 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flagellin_C,Flagellin_N k141_1535_2 223926.28805771 0.0 1123.0 COG1256@1|root,COG1256@2|Bacteria,1MV2M@1224|Proteobacteria,1RMEA@1236|Gammaproteobacteria,1XU4C@135623|Vibrionales 135623|Vibrionales N flagellar hook-associated protein flgK - - ko:K02396 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C k141_1535_3 223926.28805770 1.14e-185 520.0 COG1705@1|root,COG3951@1|root,COG1705@2|Bacteria,COG3951@2|Bacteria,1MX2W@1224|Proteobacteria,1RPGY@1236|Gammaproteobacteria,1XSX3@135623|Vibrionales 135623|Vibrionales N Flagellar rod assembly protein muramidase FlgJ flgJ GO:0003674,GO:0005198 - ko:K02395 - - - - ko00000,ko02035 - - - Glucosaminidase,Rod-binding k141_1535_4 223926.28805769 4.48e-238 657.0 COG1706@1|root,COG1706@2|Bacteria,1MVKW@1224|Proteobacteria,1RMRB@1236|Gammaproteobacteria,1XTSD@135623|Vibrionales 135623|Vibrionales N Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation flgI GO:0003674,GO:0005198,GO:0005575,GO:0005623,GO:0009288,GO:0009425,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464 - ko:K02394 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FlgI k141_1535_5 1116375.VEJY3_03575 6.43e-165 463.0 COG2063@1|root,COG2063@2|Bacteria,1RDEY@1224|Proteobacteria,1S3XK@1236|Gammaproteobacteria,1XUAA@135623|Vibrionales 135623|Vibrionales N Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation flgH GO:0003674,GO:0005198,GO:0005575,GO:0005623,GO:0009288,GO:0009425,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464 - ko:K02393 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FlgH k141_1535_6 223926.28805767 3.03e-183 510.0 COG4786@1|root,COG4786@2|Bacteria,1MVMA@1224|Proteobacteria,1RMJ2@1236|Gammaproteobacteria,1XU20@135623|Vibrionales 135623|Vibrionales N Belongs to the flagella basal body rod proteins family flgG - - ko:K02392 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C k141_1535_7 1219076.N646_2929 1.87e-166 466.0 COG4787@1|root,COG4787@2|Bacteria,1NZWQ@1224|Proteobacteria,1RNVX@1236|Gammaproteobacteria,1XTW3@135623|Vibrionales 135623|Vibrionales N Belongs to the flagella basal body rod proteins family flgF - - ko:K02391 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C k141_1535_8 223926.28805764 3.61e-302 825.0 COG1749@1|root,COG1749@2|Bacteria,1MU5J@1224|Proteobacteria,1RMWX@1236|Gammaproteobacteria,1XU4Y@135623|Vibrionales 135623|Vibrionales N Flagellar hook protein FlgE flgE - - ko:K02390 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FlaE,Flg_bb_rod,Flg_bbr_C k141_1535_9 1116375.VEJY3_03555 1.66e-153 432.0 COG1843@1|root,COG1843@2|Bacteria,1MXCG@1224|Proteobacteria,1RPZI@1236|Gammaproteobacteria,1XTM4@135623|Vibrionales 135623|Vibrionales N Required for flagellar hook formation. May act as a scaffolding protein flgD - - ko:K02389 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FLgD_tudor,FlgD,FlgD_ig k141_1535_10 1219077.VAZ01S_073_00020 1.7e-85 253.0 COG1558@1|root,COG1558@2|Bacteria,1RHI3@1224|Proteobacteria,1S653@1236|Gammaproteobacteria,1XWW3@135623|Vibrionales 135623|Vibrionales N Belongs to the flagella basal body rod proteins family flgC - - ko:K02388 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C k141_1535_11 1116375.VEJY3_03545 1.49e-87 257.0 COG1815@1|root,COG1815@2|Bacteria,1MZ8P@1224|Proteobacteria,1S9DS@1236|Gammaproteobacteria,1XWV7@135623|Vibrionales 135623|Vibrionales N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body flgB - - ko:K02387 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod k141_1535_12 223926.28805760 1.09e-187 522.0 COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,1RMFK@1236|Gammaproteobacteria,1XSQ2@135623|Vibrionales 135623|Vibrionales NT Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP cheR GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0050896 2.1.1.80 ko:K00575 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko01000,ko02035 - - - CheR,CheR_N k141_1535_13 1116375.VEJY3_03535 9.49e-121 351.0 COG0784@1|root,COG0835@1|root,COG0784@2|Bacteria,COG0835@2|Bacteria,1N81M@1224|Proteobacteria,1RPS1@1236|Gammaproteobacteria,1XSWX@135623|Vibrionales 135623|Vibrionales T COG0835 Chemotaxis signal transduction protein cheV - - ko:K03415 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - CheW,Response_reg k141_518_1 218284.CCDN010000002_gene2745 6.08e-54 178.0 28PJY@1|root,2ZC9F@2|Bacteria,1V390@1239|Firmicutes,4HG7F@91061|Bacilli,1ZDN7@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF1836) ykrK - - - - - - - - - - - DUF1836 k141_6549_1 1042377.AFPJ01000052_gene1582 5.17e-32 127.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria,4651V@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec k141_6549_2 1042377.AFPJ01000052_gene1581 2.37e-09 57.4 COG3712@1|root,COG3712@2|Bacteria,1MZCK@1224|Proteobacteria,1S88I@1236|Gammaproteobacteria,467V5@72275|Alteromonadaceae 1236|Gammaproteobacteria PT Domain of unknown function (DUF4880) - - - ko:K07165 - - - - ko00000 - - - DUF4880,DUF4974,FecR k141_14758_1 1454004.AW11_03580 2.22e-120 363.0 COG1752@1|root,COG1752@2|Bacteria,1MUI6@1224|Proteobacteria,2VHA3@28216|Betaproteobacteria 28216|Betaproteobacteria S Phospholipase, patatin family - - - ko:K07001 - - - - ko00000 - - - Patatin k141_19633_1 223926.28806353 3.85e-84 263.0 COG0624@1|root,COG0624@2|Bacteria,1MWJS@1224|Proteobacteria,1RZXV@1236|Gammaproteobacteria,1XVZK@135623|Vibrionales 135623|Vibrionales E Peptidase dimerisation domain - - - ko:K13049 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20,Peptidase_M28 k141_35074_1 1042377.AFPJ01000012_gene1389 3.78e-44 152.0 COG1612@1|root,COG1612@2|Bacteria,1MVJ4@1224|Proteobacteria,1RQWB@1236|Gammaproteobacteria,463XT@72275|Alteromonadaceae 1236|Gammaproteobacteria O protein required for cytochrome oxidase assembly ctaA - - ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 M00154 R07412 RC00769 ko00000,ko00001,ko00002,ko03029 3.D.4.4 - - COX15-CtaA k141_35074_2 1453501.JELR01000002_gene1069 2.38e-38 135.0 COG1999@1|root,COG1999@2|Bacteria,1N6R6@1224|Proteobacteria,1SC88@1236|Gammaproteobacteria,46868@72275|Alteromonadaceae 1236|Gammaproteobacteria S signal sequence binding - - - - - - - - - - - - - k141_11377_1 342113.DM82_2998 3.35e-24 103.0 COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,2VKBE@28216|Betaproteobacteria 28216|Betaproteobacteria Q Flavin containing amine oxidoreductase crtI - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 ko:K10027 ko00906,ko01100,ko01110,map00906,map01100,map01110 - R04787,R04798,R04800,R09691,R09692 RC01214,RC02088,RC02605 ko00000,ko00001,ko01000 - - - Amino_oxidase k141_7632_1 1033739.CAEU01000055_gene430 1.47e-35 124.0 COG0693@1|root,COG0693@2|Bacteria,1V3I7@1239|Firmicutes,4HFNG@91061|Bacilli,26EUU@186818|Planococcaceae 91061|Bacilli S DJ-1/PfpI family yfkM - 3.5.1.124 ko:K05520 - - - - ko00000,ko01000,ko01002 - - - DJ-1_PfpI k141_7632_2 218284.CCDN010000002_gene2234 1.21e-34 120.0 COG4840@1|root,COG4840@2|Bacteria,1VEYR@1239|Firmicutes,4HNKK@91061|Bacilli,1ZJ0U@1386|Bacillus 91061|Bacilli S Belongs to the UPF0435 family yfkK - - - - - - - - - - - DUF1128 k141_7632_3 1133850.SHJG_5149 4.6e-23 95.5 COG0394@1|root,COG0394@2|Bacteria,2IM0Q@201174|Actinobacteria 201174|Actinobacteria T Belongs to the low molecular weight phosphotyrosine protein phosphatase family ptpA - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - LMWPc k141_7632_4 218284.CCDN010000002_gene2235 5.63e-12 62.4 COG4980@1|root,COG4980@2|Bacteria,1VGY5@1239|Firmicutes,4HPNI@91061|Bacilli,1ZIVN@1386|Bacillus 91061|Bacilli S gas vesicle protein yfkI - - - - - - - - - - - - k141_12636_1 172045.KS04_18350 0.000122 44.3 COG1403@1|root,COG1403@2|Bacteria 2|Bacteria V endonuclease activity - - - ko:K07451 - - - - ko00000,ko01000,ko02048 - - - HNH,HNH_5 k141_24303_2 411465.PEPMIC_00025 3.34e-45 150.0 COG0677@1|root,COG0677@2|Bacteria,1V98N@1239|Firmicutes 1239|Firmicutes M UDP-N-acetyl-D-mannosamine dehydrogenase activity - - - - - - - - - - - - - k141_5420_1 886293.Sinac_6886 1.25e-129 388.0 COG0843@1|root,COG0843@2|Bacteria,2IXCQ@203682|Planctomycetes 203682|Planctomycetes C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B - - 1.9.3.1 ko:K02274 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6 - - COX1 k141_6550_1 665959.HMPREF1013_04190 3.1e-35 126.0 COG3279@1|root,COG3279@2|Bacteria,1V14X@1239|Firmicutes,4HDIC@91061|Bacilli,1ZC3U@1386|Bacillus 91061|Bacilli T COG3279 Response regulator of the LytR AlgR family - - - ko:K07705 ko02020,map02020 M00492 - - ko00000,ko00001,ko00002,ko02022 - - - LytTR,Response_reg k141_35075_1 933115.GPDM_00835 1.56e-78 248.0 COG3395@1|root,COG3395@2|Bacteria,1TRZ8@1239|Firmicutes,4HAS4@91061|Bacilli,26CYU@186818|Planococcaceae 91061|Bacilli S Putative nucleotide-binding of sugar-metabolising enzyme - - - - - - - - - - - - DUF1357_C,DUF1537 k141_10237_1 768066.HELO_2803 6.97e-112 332.0 COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,1RMR6@1236|Gammaproteobacteria,1XH7R@135619|Oceanospirillales 135619|Oceanospirillales Q C4-dicarboxylate ABC transporter permease - - - - - - - - - - - - DctM k141_723_1 1042377.AFPJ01000037_gene2986 1.04e-130 386.0 COG0366@1|root,COG0366@2|Bacteria,1MVKX@1224|Proteobacteria,1RMXP@1236|Gammaproteobacteria,4642X@72275|Alteromonadaceae 1236|Gammaproteobacteria G Alpha amylase ycjM - 2.4.1.7 ko:K00690 ko00500,map00500 - R00803 RC00028 ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,DUF3459,Malt_amylase_C k141_21971_1 861299.J421_3262 1.23e-13 69.3 COG4974@1|root,COG4974@2|Bacteria,1ZTAH@142182|Gemmatimonadetes 142182|Gemmatimonadetes D Phage integrase, N-terminal SAM-like domain xerD - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase k141_13845_1 1294265.JCM21738_1859 3.12e-50 168.0 COG1879@1|root,COG1879@2|Bacteria,1TSUI@1239|Firmicutes,4HBMV@91061|Bacilli,1ZC6R@1386|Bacillus 91061|Bacilli G Periplasmic binding protein domain - - - ko:K02058 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - Peripla_BP_4 k141_35106_1 1245469.S58_59180 6.96e-112 329.0 COG1348@1|root,COG1348@2|Bacteria,1MVTE@1224|Proteobacteria,2TSKC@28211|Alphaproteobacteria,3JW6P@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P Belongs to the NifH BchL ChlL family bchX - 1.3.7.14,1.3.7.15 ko:K11333 ko00860,ko01110,map00860,map01110 - R09053,R09060 RC01008 ko00000,ko00001,ko01000 - - - Fer4_NifH k141_19641_1 218284.CCDN010000001_gene657 2.66e-55 177.0 COG2323@1|root,COG2323@2|Bacteria,1V3NW@1239|Firmicutes,4HHEY@91061|Bacilli,1ZDIR@1386|Bacillus 91061|Bacilli S membrane yrbG - - - - - - - - - - - DUF421 k141_23271_1 765910.MARPU_13540 4.38e-76 246.0 COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,1RMWP@1236|Gammaproteobacteria,1WVWH@135613|Chromatiales 135613|Chromatiales G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate - - 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C,Transketolase_N k141_16021_1 525904.Tter_1230 1.78e-35 133.0 COG1575@1|root,COG1575@2|Bacteria,2NPNN@2323|unclassified Bacteria 2|Bacteria H UbiA prenyltransferase family menA - 2.5.1.74 ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R05617,R06858,R10757 RC02935,RC02936,RC03264 ko00000,ko00001,ko00002,ko01000,ko01006 - - - UbiA k141_25666_2 1453501.JELR01000001_gene2467 7.96e-31 110.0 COG2991@1|root,COG2991@2|Bacteria,1N8TF@1224|Proteobacteria,1SCB5@1236|Gammaproteobacteria,468F5@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria - - - ko:K05952 - - - - ko00000 - - - NqrM k141_25666_3 1279017.AQYJ01000025_gene725 1.04e-95 287.0 COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,1RNMZ@1236|Gammaproteobacteria,46547@72275|Alteromonadaceae 1236|Gammaproteobacteria H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein apbE GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016740,GO:0017013,GO:0019538,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0031975,GO:0036094,GO:0036211,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0071944,GO:0071949,GO:0097159,GO:0098552,GO:0098567,GO:1901265,GO:1901363,GO:1901564 2.7.1.180 ko:K03734 - - - - ko00000,ko01000 - - - ApbE k141_33894_1 218284.CCDN010000002_gene2038 5.46e-116 358.0 COG0457@1|root,COG0457@2|Bacteria,1UATF@1239|Firmicutes,4HE1D@91061|Bacilli,1ZBPM@1386|Bacillus 91061|Bacilli S ATPase. Has a role at an early stage in the morphogenesis of the spore coat - - - - - - - - - - - - Dynamin_N,TPR_8 k141_12656_1 1078085.HMPREF1210_03099 1.88e-46 169.0 COG1404@1|root,COG1404@2|Bacteria,1TPH1@1239|Firmicutes,4HBQH@91061|Bacilli,26GW2@186818|Planococcaceae 91061|Bacilli O Peptidase inhibitor I9 prtS - 3.4.21.110,3.4.21.96 ko:K01361,ko:K08652 - - - - ko00000,ko01000,ko01002,ko03110 - - - FIVAR,Gram_pos_anchor,Inhibitor_I9,PA,Peptidase_S8,SLH,YSIRK_signal,fn3_5 k141_11406_1 1274524.BSONL12_03824 3.8e-27 108.0 COG3486@1|root,COG3486@2|Bacteria,1UZAQ@1239|Firmicutes,4HBD0@91061|Bacilli,1ZQMD@1386|Bacillus 91061|Bacilli Q Flavin-binding monooxygenase-like - - 1.14.13.59 ko:K03897 ko00310,ko01120,map00310,map01120 - R00448 RC00298 ko00000,ko00001,ko01000 - - - K_oxygenase k141_11406_2 218284.CCDN010000006_gene3574 5.59e-93 276.0 COG1670@1|root,COG1670@2|Bacteria,1V3P3@1239|Firmicutes,4HH0Y@91061|Bacilli,1ZG9J@1386|Bacillus 91061|Bacilli J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins - - - - - - - - - - - - Acetyltransf_8 k141_11406_3 218284.CCDN010000006_gene3575 8.41e-25 102.0 COG4264@1|root,COG4264@2|Bacteria,1V0HB@1239|Firmicutes,4HAUQ@91061|Bacilli,1ZCKN@1386|Bacillus 91061|Bacilli Q Siderophore biosynthesis protein asbA - - - - - - - - - - - FhuF,IucA_IucC k141_13846_1 1294265.JCM21738_2587 2.93e-135 412.0 COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,4HABE@91061|Bacilli,1ZPZA@1386|Bacillus 91061|Bacilli EF Carbamoyl-phosphate synthetase ammonia chain carB GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS k141_24331_1 218284.CCDN010000001_gene1026 6.17e-31 115.0 COG0119@1|root,COG0119@2|Bacteria,1TQG3@1239|Firmicutes,4HA1U@91061|Bacilli,1ZC18@1386|Bacillus 91061|Bacilli E Hydroxymethylglutaryl-CoA lyase yngG - 4.1.3.4 ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 M00036,M00088 R01360,R08090 RC00502,RC00503,RC01118,RC01946 ko00000,ko00001,ko00002,ko01000 - - - HMGL-like k141_27749_1 240016.ABIZ01000001_gene1413 5.98e-123 370.0 COG3174@1|root,COG3174@2|Bacteria,46VTJ@74201|Verrucomicrobia 74201|Verrucomicrobia S Domain of unknown function (DUF4010) - - - - - - - - - - - - DUF4010,MgtC k141_27749_5 1122613.ATUP01000001_gene316 3.68e-165 495.0 COG0577@1|root,COG0577@2|Bacteria,1MW6D@1224|Proteobacteria,2TTJZ@28211|Alphaproteobacteria,43ZIX@69657|Hyphomonadaceae 28211|Alphaproteobacteria V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD k141_29068_1 1122915.AUGY01000100_gene4686 5.96e-11 62.8 COG1053@1|root,COG1053@2|Bacteria,1TSG9@1239|Firmicutes,4HE2J@91061|Bacilli,26QE0@186822|Paenibacillaceae 91061|Bacilli C FAD dependent oxidoreductase - - - - - - - - - - - - FAD_oxidored k141_29068_2 1121938.AUDY01000009_gene2291 2.09e-08 57.0 COG1649@1|root,COG1649@2|Bacteria 2|Bacteria F PFAM Uncharacterised BCR, COG1649 - - - - - - - - - - - - GHL10 k141_19642_2 1501230.ET33_15885 0.000504 42.0 COG4326@1|root,COG4326@2|Bacteria,1TPEA@1239|Firmicutes,4HBPW@91061|Bacilli,26SRV@186822|Paenibacillaceae 91061|Bacilli S Sporulation control protein spo0M - - ko:K06377 - - - - ko00000 - - - Spo0M k141_1691_1 218284.CCDN010000006_gene3605 9.91e-131 381.0 COG4447@1|root,COG4447@2|Bacteria,1TRJ4@1239|Firmicutes,4HBUI@91061|Bacilli,1ZCUG@1386|Bacillus 91061|Bacilli S cellulose binding - - - - - - - - - - - - Sortilin-Vps10 k141_30156_1 1196031.ALEG01000008_gene5039 2.13e-09 58.2 COG1113@1|root,COG1113@2|Bacteria,1TP97@1239|Firmicutes,4H9QX@91061|Bacilli,1ZDGG@1386|Bacillus 91061|Bacilli E COG1113 Gamma-aminobutyrate permease and related permeases ycgH GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03293 - - - - ko00000 2.A.3.1 - - AA_permease k141_30156_2 218284.CCDN010000002_gene2600 5.05e-93 284.0 COG0477@1|root,COG2814@2|Bacteria,1TQEW@1239|Firmicutes,4HASU@91061|Bacilli,1ZB5B@1386|Bacillus 91061|Bacilli EGP COG0477 Permeases of the major facilitator superfamily ymfD - - ko:K08221 - - - - ko00000,ko02000 2.A.1.32 - - MFS_1,MFS_2,Sugar_tr k141_25668_1 1249627.D779_3179 3.88e-72 220.0 COG1238@1|root,COG1238@2|Bacteria,1RHUV@1224|Proteobacteria,1S69A@1236|Gammaproteobacteria,1WYYQ@135613|Chromatiales 135613|Chromatiales S PFAM SNARE associated Golgi protein - - - - - - - - - - - - SNARE_assoc k141_26981_1 338969.Rfer_3496 3.69e-94 284.0 28HGI@1|root,2Z7SC@2|Bacteria,1MWKC@1224|Proteobacteria,2VP5Q@28216|Betaproteobacteria,4AGW7@80864|Comamonadaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k141_7646_1 218284.CCDN010000006_gene3685 4.18e-109 337.0 COG0653@1|root,COG0653@2|Bacteria,1TPEY@1239|Firmicutes,4HA22@91061|Bacilli,1ZAXF@1386|Bacillus 91061|Bacilli U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW k141_23273_2 1406785.U5PTZ8_9CAUD 1.83e-44 148.0 4QFIE@10239|Viruses,4QUGB@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k141_18517_1 1116375.VEJY3_19926 0.0 899.0 COG3044@1|root,COG3044@2|Bacteria,1Q603@1224|Proteobacteria,1RZ7J@1236|Gammaproteobacteria,1XUFF@135623|Vibrionales 135623|Vibrionales S ATPase of the ABC class - - - - - - - - - - - - ABC_ATPase k141_18517_2 1116375.VEJY3_19921 4e-116 352.0 COG2200@1|root,COG2203@1|root,COG2200@2|Bacteria,COG2203@2|Bacteria,1RGKE@1224|Proteobacteria,1T1I8@1236|Gammaproteobacteria,1XUWZ@135623|Vibrionales 135623|Vibrionales T GGDEF family - - 3.1.4.52 ko:K20962 ko05111,map05111 - - - ko00000,ko00001,ko01000 - - - EAL,GAF,GAF_2,GGDEF k141_20739_1 218284.CCDN010000008_gene4142 2.07e-94 289.0 COG1169@1|root,COG1169@2|Bacteria,1TSRT@1239|Firmicutes,4H9K8@91061|Bacilli,1ZB3V@1386|Bacillus 91061|Bacilli HQ Isochorismate synthase menF - 5.4.4.2 ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 M00116 R01717 RC00588 ko00000,ko00001,ko00002,ko01000 - - - Chorismate_bind k141_14777_1 218284.CCDN010000001_gene1919 3.69e-187 528.0 COG1776@1|root,COG1886@1|root,COG1776@2|Bacteria,COG1886@2|Bacteria,1TPT8@1239|Firmicutes,4HC56@91061|Bacilli,1ZB7S@1386|Bacillus 91061|Bacilli N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation fliY GO:0003674,GO:0003824,GO:0004721,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006935,GO:0008150,GO:0008152,GO:0009605,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0032879,GO:0036211,GO:0040011,GO:0040012,GO:0042221,GO:0042330,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0050896,GO:0051270,GO:0065007,GO:0071704,GO:0140096,GO:1901564,GO:1902021,GO:2000145 - ko:K02417 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 - - CheC,FliMN_C k141_14777_2 218284.CCDN010000001_gene1920 1.03e-36 132.0 COG1868@1|root,COG1868@2|Bacteria,1TPTM@1239|Firmicutes,4HAAY@91061|Bacilli,1ZCI6@1386|Bacillus 91061|Bacilli N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation fliM GO:0005575,GO:0005623,GO:0005886,GO:0006935,GO:0008150,GO:0009288,GO:0009425,GO:0009605,GO:0016020,GO:0040011,GO:0042221,GO:0042330,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0050896,GO:0050918,GO:0071944 - ko:K02416 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02035 - - - FliM,FliMN_C k141_35110_1 935836.JAEL01000123_gene2177 2.16e-22 89.7 COG1695@1|root,COG1695@2|Bacteria,1VAGB@1239|Firmicutes,4HKBS@91061|Bacilli,1ZHV2@1386|Bacillus 91061|Bacilli K Transcriptional regulator padR - - ko:K10947 - - - - ko00000,ko03000 - - - PadR k141_35110_2 1347369.CCAD010000065_gene3799 1.05e-56 184.0 COG4858@1|root,COG4858@2|Bacteria,1V8U0@1239|Firmicutes,4HIYU@91061|Bacilli,1ZQEA@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - DUF1129 k141_32539_1 1394175.AWUN01000001_gene1309 3.5e-20 99.8 COG0308@1|root,COG0308@2|Bacteria,2GJJ4@201174|Actinobacteria,4CZH4@85004|Bifidobacteriales 201174|Actinobacteria E Peptidase family M1 domain pepN - 3.4.11.2 ko:K01256,ko:K08776 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - ERAP1_C,Peptidase_M1 k141_32539_3 1127673.GLIP_0366 3.48e-163 461.0 COG2116@1|root,COG2116@2|Bacteria,1MU0W@1224|Proteobacteria,1RQ6K@1236|Gammaproteobacteria,464M9@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG2116 Formate nitrite family of transporters fnt - - ko:K06212,ko:K21993 - - - - ko00000,ko02000 1.A.16.1.1,1.A.16.1.3,1.A.16.2 - - Form_Nir_trans k141_10239_2 925775.XVE_0577 5.93e-145 431.0 COG1506@1|root,COG1506@2|Bacteria,1MUJ3@1224|Proteobacteria,1RPAW@1236|Gammaproteobacteria,1X6AG@135614|Xanthomonadales 135614|Xanthomonadales E X-Pro dipeptidyl-peptidase (S15 family) - - - - - - - - - - - - Peptidase_S9 k141_25670_1 1169144.KB910940_gene2537 6.88e-86 271.0 COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4H9ZK@91061|Bacilli,1ZCFC@1386|Bacillus 91061|Bacilli S ABC transporter - - - - - - - - - - - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn k141_24333_1 1042377.AFPJ01000014_gene1633 2.78e-89 284.0 COG1651@1|root,COG1651@2|Bacteria 2|Bacteria O Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - Thioredoxin_4,VKOR k141_35111_1 1121104.AQXH01000001_gene1413 4.7e-63 218.0 COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1IPZZ@117747|Sphingobacteriia 976|Bacteroidetes V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran k141_2900_1 1219076.N646_1026 1.09e-122 350.0 COG0558@1|root,COG0558@2|Bacteria,1RCZ7@1224|Proteobacteria,1S465@1236|Gammaproteobacteria,1XT7Y@135623|Vibrionales 135623|Vibrionales I Belongs to the CDP-alcohol phosphatidyltransferase class-I family pgsA - 2.7.8.5 ko:K00995 ko00564,ko01100,map00564,map01100 - R01801 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 - - - CDP-OH_P_transf k141_2900_2 1219076.N646_1027 1.85e-159 461.0 COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,1RNGV@1236|Gammaproteobacteria,1XT19@135623|Vibrionales 135623|Vibrionales L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision uvrC GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009380,GO:0009381,GO:0009987,GO:0016787,GO:0016788,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - ko:K03703 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - GIY-YIG,HHH,HHH_5,UVR,UvrC_HhH_N k141_21974_1 218284.CCDN010000005_gene3479 3.68e-85 260.0 COG1226@1|root,COG1226@2|Bacteria,1TS7X@1239|Firmicutes,4HCIB@91061|Bacilli,1ZCD3@1386|Bacillus 91061|Bacilli P COG1226 Kef-type K transport systems yugO - - ko:K10716 - - - - ko00000,ko02000 1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6 - - Ion_trans_2,TrkA_N k141_14778_1 1208321.D104_10325 1.88e-81 251.0 COG1073@1|root,COG1073@2|Bacteria,1MXJ3@1224|Proteobacteria,1RRZK@1236|Gammaproteobacteria 1236|Gammaproteobacteria S hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - - - - - - - - - - Abhydrolase_6,DUF1100,Peptidase_S9 k141_14778_2 400668.Mmwyl1_3145 4.82e-29 112.0 COG0346@1|root,COG0346@2|Bacteria,1MVVU@1224|Proteobacteria,1RQQE@1236|Gammaproteobacteria,1XKWW@135619|Oceanospirillales 135619|Oceanospirillales E PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - - - - - - - - - - Glyoxalase k141_27750_1 1116375.VEJY3_03050 0.0 957.0 COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,1RMRN@1236|Gammaproteobacteria,1XTXA@135623|Vibrionales 135623|Vibrionales F Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate purL GO:0003674,GO:0003824,GO:0004642,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - AIRS_C,GATase_5 k141_35112_1 935836.JAEL01000033_gene4085 2.67e-93 283.0 COG0281@1|root,COG0281@2|Bacteria,1TPJ3@1239|Firmicutes,4H9WR@91061|Bacilli,1ZEFJ@1386|Bacillus 91061|Bacilli C Malate dehydrogenase - - 1.1.1.38 ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 - R00214 RC00105 ko00000,ko00001,ko01000 - - - Malic_M,malic k141_1693_1 1294265.JCM21738_2253 2.08e-114 332.0 COG0624@1|root,COG0624@2|Bacteria,1TPEG@1239|Firmicutes,4HC14@91061|Bacilli,1ZBI2@1386|Bacillus 91061|Bacilli E Dipeptidase ytjP - 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20 k141_6569_1 1453501.JELR01000005_gene1781 2.14e-276 792.0 COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,1RPV3@1236|Gammaproteobacteria,466FE@72275|Alteromonadaceae 1236|Gammaproteobacteria NU Neisseria PilC beta-propeller domain pilY - - ko:K02674 - - - - ko00000,ko02035,ko02044 - - - Neisseria_PilC,PA14 k141_16024_1 218284.CCDN010000007_gene3960 1.06e-187 551.0 COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,1TQAD@1239|Firmicutes,4HCMS@91061|Bacilli,1ZBF6@1386|Bacillus 91061|Bacilli EI Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly icmF GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046906,GO:0046983,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 ko:K11942 - - - - ko00000,ko01000 - - - ArgK,B12-binding,MM_CoA_mutase k141_4185_1 339670.Bamb_2958 1.91e-20 93.2 COG1752@1|root,COG1752@2|Bacteria,1PIHH@1224|Proteobacteria,2VHKX@28216|Betaproteobacteria,1K1GW@119060|Burkholderiaceae 28216|Betaproteobacteria S Patatin-like phospholipase - - - ko:K07001 - - - - ko00000 - - - Patatin k141_32540_1 218284.CCDN010000005_gene3248 3.84e-216 602.0 COG2182@1|root,COG2182@2|Bacteria,1TPU9@1239|Firmicutes,4HBHE@91061|Bacilli,1ZBWG@1386|Bacillus 91061|Bacilli G COG2182 Maltose-binding periplasmic proteins domains cycB - - ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 M00207,M00491,M00599 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.16,3.A.1.1.2,3.A.1.1.38 - - SBP_bac_8 k141_10240_2 96561.Dole_2132 2.16e-77 241.0 COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42QN5@68525|delta/epsilon subdivisions,2WMD7@28221|Deltaproteobacteria,2MJC9@213118|Desulfobacterales 28221|Deltaproteobacteria V PFAM ABC transporter related - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_12659_2 1453501.JELR01000001_gene2299 3.97e-90 270.0 COG1187@1|root,COG1187@2|Bacteria,1R9VV@1224|Proteobacteria,1S1ZX@1236|Gammaproteobacteria,466JR@72275|Alteromonadaceae 1236|Gammaproteobacteria J Belongs to the pseudouridine synthase RsuA family rluE GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.20 ko:K06181 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2 k141_26984_2 1032480.MLP_14420 4.77e-22 94.4 COG1171@1|root,COG1171@2|Bacteria,2GJAG@201174|Actinobacteria,4DTE8@85009|Propionibacteriales 201174|Actinobacteria E Pyridoxal-phosphate dependent enzyme - - 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - - PALP k141_35113_1 1279017.AQYJ01000027_gene1684 1.02e-90 283.0 COG3850@1|root,COG3850@2|Bacteria,1MWZT@1224|Proteobacteria,1RNPP@1236|Gammaproteobacteria,465S0@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG3850 Signal transduction histidine kinase, nitrate nitrite-specific narQ GO:0000155,GO:0000160,GO:0001101,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010167,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0035556,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070887,GO:0071229,GO:0071241,GO:0071249,GO:0071250,GO:0071704,GO:0071944,GO:0080033,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170 2.7.13.3 ko:K07673,ko:K07674 ko02020,map02020 M00471,M00472 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA_3,PilJ k141_5467_2 1042377.AFPJ01000027_gene2666 4.84e-36 122.0 2E4UA@1|root,32ZNM@2|Bacteria,1NAZR@1224|Proteobacteria,1SC82@1236|Gammaproteobacteria,4693Y@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_5467_3 1453501.JELR01000002_gene108 0.0 1225.0 COG3591@1|root,COG3591@2|Bacteria,1MX71@1224|Proteobacteria,1RRGG@1236|Gammaproteobacteria,465PD@72275|Alteromonadaceae 1236|Gammaproteobacteria E Peptidase S46 - - - - - - - - - - - - Peptidase_S46 k141_21999_1 1453501.JELR01000005_gene1589 8.73e-101 310.0 COG0366@1|root,COG0366@2|Bacteria,1MU90@1224|Proteobacteria,1RQ1S@1236|Gammaproteobacteria,465MB@72275|Alteromonadaceae 1236|Gammaproteobacteria G Alpha-amylase domain malS GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0004556,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009311,GO:0009313,GO:0009987,GO:0016052,GO:0016160,GO:0016787,GO:0016798,GO:0030288,GO:0030313,GO:0030978,GO:0030980,GO:0031975,GO:0042597,GO:0043167,GO:0043169,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044464,GO:0046872,GO:0051691,GO:0051692,GO:0071704,GO:1901575 3.2.1.1 ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 - R02108,R02112,R11262 - ko00000,ko00001,ko01000 - GH13 iECABU_c1320.ECABU_c40140,iECP_1309.ECP_3675,iECSE_1348.ECSE_3847,iPC815.YPO4080,ic_1306.c4392 Alpha-amylase k141_12683_1 42565.FP66_05085 1.01e-95 292.0 COG0733@1|root,COG0733@2|Bacteria,1MUZJ@1224|Proteobacteria,1RPCT@1236|Gammaproteobacteria,1XIJV@135619|Oceanospirillales 135619|Oceanospirillales S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family - - - ko:K03308 - - - - ko00000 2.A.22.4,2.A.22.5 - - SNF k141_5686_2 42565.FP66_10975 2.74e-92 297.0 COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,1RNA6@1236|Gammaproteobacteria,1XH98@135619|Oceanospirillales 135619|Oceanospirillales D Required for chromosome condensation and partitioning smc - - ko:K03529 - - - - ko00000,ko03036 - - - SMC_N,SMC_hinge k141_35337_1 1116375.VEJY3_00800 6.42e-132 390.0 COG4166@1|root,COG4166@2|Bacteria,1MUVU@1224|Proteobacteria,1RMA1@1236|Gammaproteobacteria,1XUMM@135623|Vibrionales 135623|Vibrionales E ABC-type oligopeptide transport system, periplasmic component - - - ko:K13893 ko02010,map02010 M00349 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.21,3.A.1.5.24 - - SBP_bac_5 k141_16214_1 290398.Csal_0216 1.36e-112 343.0 COG1289@1|root,COG1289@2|Bacteria,1MX9H@1224|Proteobacteria,1RPFA@1236|Gammaproteobacteria 1236|Gammaproteobacteria U Forms an efflux pump with AaeA. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell - - - - - - - - - - - - FUSC k141_24612_1 1294265.JCM21738_1738 1.16e-116 337.0 COG5609@1|root,COG5609@2|Bacteria,1V66Q@1239|Firmicutes,4HICY@91061|Bacilli,1ZFWY@1386|Bacillus 91061|Bacilli S Uncharacterized conserved protein (DUF2294) - - - - - - - - - - - - DUF2294 k141_18827_1 1227349.C170_00954 5.17e-78 241.0 COG0444@1|root,COG0444@2|Bacteria,1V1QM@1239|Firmicutes,4HFZ7@91061|Bacilli,26TU2@186822|Paenibacillaceae 91061|Bacilli EP Peptide ABC transporter ATP-binding protein - - 3.6.3.24 ko:K15587 ko02010,map02010 M00440 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.5 - - ABC_tran k141_6802_1 218284.CCDN010000006_gene3542 1.78e-83 256.0 COG1979@1|root,COG1979@2|Bacteria,1TPS3@1239|Firmicutes,4HT1J@91061|Bacilli,1ZEGP@1386|Bacillus 91061|Bacilli C Iron-containing alcohol dehydrogenase - - - ko:K19955 - - - - ko00000,ko01000 - - - Fe-ADH k141_6802_2 218284.CCDN010000006_gene3541 7.52e-29 106.0 2AD85@1|root,312X5@2|Bacteria,1V735@1239|Firmicutes,4HIXA@91061|Bacilli,1ZGBJ@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_19858_1 1279017.AQYJ01000028_gene2074 4.37e-88 287.0 COG1729@1|root,COG1729@2|Bacteria,1MX82@1224|Proteobacteria,1T32S@1236|Gammaproteobacteria,465Q0@72275|Alteromonadaceae 1236|Gammaproteobacteria O protein conserved in bacteria - - - - - - - - - - - - TPR_16,TPR_6,TPR_8,YfiO k141_29291_2 218284.CCDN010000001_gene174 2.89e-87 264.0 COG1277@1|root,COG1277@2|Bacteria,1V2H6@1239|Firmicutes,4HC35@91061|Bacilli,1ZDQU@1386|Bacillus 91061|Bacilli S ABC-type transport system involved in multi-copper enzyme maturation, permease component - - - - - - - - - - - - ABC2_membrane_2,ABC2_membrane_3 k141_9231_2 1042377.AFPJ01000007_gene1859 4.31e-84 249.0 COG0848@1|root,COG0848@2|Bacteria,1N0ZA@1224|Proteobacteria,1S90K@1236|Gammaproteobacteria,467KB@72275|Alteromonadaceae 1236|Gammaproteobacteria U Biopolymer transport protein ExbD/TolR exbD1 - - ko:K03559 - - - - ko00000,ko02000 1.A.30.2.1 - - ExbD k141_9231_3 1279017.AQYJ01000025_gene621 4.26e-116 335.0 COG0811@1|root,COG0811@2|Bacteria,1QNJ1@1224|Proteobacteria,1RQWT@1236|Gammaproteobacteria,466BI@72275|Alteromonadaceae 1236|Gammaproteobacteria U COG0811 Biopolymer transport proteins exbB - - ko:K03561 - - - - ko00000,ko02000 1.A.30.2.1 - - MotA_ExbB k141_9231_5 1000565.METUNv1_01638 3.5e-41 149.0 29TFP@1|root,30ENV@2|Bacteria,1RG86@1224|Proteobacteria,2VS6R@28216|Betaproteobacteria,2KWFR@206389|Rhodocyclales 206389|Rhodocyclales - - - - - - - - - - - - - - - k141_32768_1 1042377.AFPJ01000042_gene1076 2.47e-75 249.0 COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,1RNW3@1236|Gammaproteobacteria,464F1@72275|Alteromonadaceae 1236|Gammaproteobacteria L that it carries out the mismatch recognition step. This protein has a weak ATPase activity mutS GO:0000018,GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0008301,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030554,GO:0030983,GO:0031323,GO:0032136,GO:0032300,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1990391 - ko:K03555 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - iECW_1372.ECW_m2935,iWFL_1372.ECW_m2935 MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V k141_23548_2 1117647.M5M_09025 9.11e-307 863.0 COG1629@1|root,COG4771@2|Bacteria,1MVFB@1224|Proteobacteria,1RNMS@1236|Gammaproteobacteria,1J4QU@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec k141_23548_4 1453501.JELR01000002_gene964 3.23e-211 594.0 COG3071@1|root,COG3071@2|Bacteria,1MU7A@1224|Proteobacteria,1RMRG@1236|Gammaproteobacteria,46647@72275|Alteromonadaceae 1236|Gammaproteobacteria H enzyme of heme biosynthesis hemY GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02498 - - - - ko00000 - - - HemY_N,TPR_2 k141_14975_1 218284.CCDN010000002_gene1984 5.05e-142 410.0 COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,4HACW@91061|Bacilli,1ZC7P@1386|Bacillus 91061|Bacilli F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily purB GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS09895 ADSL_C,Lyase_1 k141_20895_1 936136.ARRT01000006_gene2139 2.84e-190 543.0 COG5361@1|root,COG5361@2|Bacteria,1NX2A@1224|Proteobacteria,2TTBA@28211|Alphaproteobacteria,4BAZE@82115|Rhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF1254) - - - - - - - - - - - - DUF1214,DUF1254 k141_37494_1 218284.CCDN010000001_gene1052 3.47e-71 215.0 COG0454@1|root,COG0456@2|Bacteria,1VAD7@1239|Firmicutes,4HKR2@91061|Bacilli,1ZHDK@1386|Bacillus 91061|Bacilli K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases ribT - - ko:K02859 - - - - ko00000 - - - Acetyltransf_1,Acetyltransf_10 k141_3084_2 218284.CCDN010000001_gene142 1.59e-172 496.0 COG1217@1|root,COG1217@2|Bacteria,1TQ5Y@1239|Firmicutes,4HAQ6@91061|Bacilli,1ZB9R@1386|Bacillus 91061|Bacilli T GTP-binding protein TypA typA - - ko:K06207 - - - - ko00000 - - - EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2 k141_6815_2 1265503.KB905169_gene198 6.34e-102 304.0 COG1028@1|root,COG1028@2|Bacteria,1MXNQ@1224|Proteobacteria,1RWMW@1236|Gammaproteobacteria,2Q7ZV@267889|Colwelliaceae 1236|Gammaproteobacteria IQ Enoyl-(Acyl carrier protein) reductase - - - - - - - - - - - - adh_short k141_32788_1 218284.CCDN010000002_gene2951 3.18e-152 434.0 COG0111@1|root,COG0111@2|Bacteria,1TSDK@1239|Firmicutes,4HAW5@91061|Bacilli,1ZCEY@1386|Bacillus 91061|Bacilli EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family ghrA - - - - - - - - - - - 2-Hacid_dh,2-Hacid_dh_C k141_9256_1 218284.CCDN010000001_gene1817 3.47e-259 715.0 COG0044@1|root,COG0044@2|Bacteria,1TP8C@1239|Firmicutes,4H9N0@91061|Bacilli,1ZQ9M@1386|Bacillus 91061|Bacilli F Amidohydrolase family hydA - 3.5.2.2 ko:K01464 ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100 M00046 R02269,R03055,R08227 RC00632,RC00680 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Amidohydro_1 k141_37511_2 1117379.BABA_25866 1.13e-17 78.2 2CJF8@1|root,2ZCAP@2|Bacteria,1V3BA@1239|Firmicutes,4HFSQ@91061|Bacilli,1ZG4X@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3189) - - - - - - - - - - - - DUF3189 k141_14998_1 218284.CCDN010000011_gene4422 3.09e-173 492.0 COG1721@1|root,COG1721@2|Bacteria,1TUWF@1239|Firmicutes,4HDRE@91061|Bacilli,1ZCAS@1386|Bacillus 91061|Bacilli S conserved protein (some members contain a von Willebrand factor type A (vWA) domain) yeaD - - - - - - - - - - - DUF58 k141_12855_1 1280001.BAOA01000021_gene716 0.0 1316.0 COG1596@1|root,COG1596@2|Bacteria,1N7GP@1224|Proteobacteria,1RQSM@1236|Gammaproteobacteria,1XUWY@135623|Vibrionales 135623|Vibrionales M Periplasmic protein involved in polysaccharide export - - - - - - - - - - - - Poly_export,SLBB k141_12855_2 1219077.VAZ01S_021_00180 2.69e-71 216.0 COG0399@1|root,COG0399@2|Bacteria,1N0QW@1224|Proteobacteria,1S8YK@1236|Gammaproteobacteria,1XXD4@135623|Vibrionales 135623|Vibrionales M 23S rRNA-intervening sequence protein - - - - - - - - - - - - 23S_rRNA_IVP k141_12855_3 1116375.VEJY3_00990 1.28e-190 535.0 COG3765@1|root,COG3765@2|Bacteria,1MXGW@1224|Proteobacteria,1RPE4@1236|Gammaproteobacteria,1XVU7@135623|Vibrionales 135623|Vibrionales M Chain length determinant protein wzz - - - - - - - - - - - GNVR,Wzz k141_23579_1 1294265.JCM21738_2813 5.74e-73 219.0 29QW2@1|root,30BWC@2|Bacteria,1U8SE@1239|Firmicutes,4IIQP@91061|Bacilli,1ZHNU@1386|Bacillus 91061|Bacilli S DsrE/DsrF/DrsH-like family - - - - - - - - - - - - DrsE_2 k141_23579_2 1294265.JCM21738_2812 4.67e-20 82.8 COG2210@1|root,COG2210@2|Bacteria,1U8S5@1239|Firmicutes,4IIQD@91061|Bacilli,1ZGXS@1386|Bacillus 91061|Bacilli S Belongs to the sulfur carrier protein TusA family - - - - - - - - - - - - - k141_11636_1 1196031.ALEG01000039_gene1849 4.02e-286 795.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,1ZBXB@1386|Bacillus 91061|Bacilli V COG1132 ABC-type multidrug transport system, ATPase and permease components mdlA - - ko:K06148,ko:K18889 ko02010,map02010 M00707 - - ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.106.13,3.A.1.106.5 - - ABC_membrane,ABC_tran k141_17365_1 42565.FP66_07245 7.69e-126 364.0 COG0825@1|root,COG0825@2|Bacteria,1MURN@1224|Proteobacteria,1RNN8@1236|Gammaproteobacteria,1XI2H@135619|Oceanospirillales 135619|Oceanospirillales I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA accA - 2.1.3.15,6.4.1.2 ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - ACCA k141_10410_1 107636.JQNK01000009_gene3513 3.67e-233 654.0 COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,2TRXG@28211|Alphaproteobacteria,370BU@31993|Methylocystaceae 28211|Alphaproteobacteria L Transposase DDE domain - - - ko:K07487 - - - - ko00000 - - - DDE_Tnp_1,DDE_Tnp_1_6,DUF772 k141_35360_1 1168065.DOK_17535 8.37e-30 109.0 COG4633@1|root,COG4633@2|Bacteria,1N6VB@1224|Proteobacteria,1SDG5@1236|Gammaproteobacteria,1J6RB@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Cupredoxin-like domain - - - - - - - - - - - - Cupredoxin_1 k141_35360_2 1268239.PALB_840 9.65e-15 75.9 COG0642@1|root,COG0642@2|Bacteria,1QTSX@1224|Proteobacteria,1T1G3@1236|Gammaproteobacteria,2Q1TY@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria T His Kinase A (phosphoacceptor) domain qseC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 ko:K07645 ko02020,ko02024,map02020,map02024 M00453 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - 2CSK_N,HATPase_c,HisKA k141_16230_1 240302.BN982_03285 1.13e-91 285.0 COG1574@1|root,COG1574@2|Bacteria,1TQ6G@1239|Firmicutes,4HC54@91061|Bacilli,3NDTX@45667|Halobacillus 91061|Bacilli S Amidohydrolase family - - - - - - - - - - - - Amidohydro_3 k141_16230_2 218284.CCDN010000001_gene1643 8.27e-259 714.0 COG0624@1|root,COG0624@2|Bacteria,1TQ0P@1239|Firmicutes,4HAE4@91061|Bacilli,1ZB60@1386|Bacillus 91061|Bacilli E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases - - 3.5.1.6,3.5.1.87,3.5.3.9 ko:K02083,ko:K06016 ko00230,ko00240,ko01100,ko01120,map00230,map00240,map01100,map01120 M00046 R00905,R02423,R04666 RC00064,RC00096 ko00000,ko00001,ko00002,ko01000,ko01002 - - - M20_dimer,Peptidase_M20,Peptidase_M28 k141_36291_2 1042377.AFPJ01000034_gene2313 2.8e-46 150.0 COG0011@1|root,COG0011@2|Bacteria,1N8R0@1224|Proteobacteria,1SCF3@1236|Gammaproteobacteria,468E8@72275|Alteromonadaceae 1236|Gammaproteobacteria S YKOF-related Family - - - - - - - - - - - - Thiamine_BP,Ykof k141_36291_3 1453501.JELR01000001_gene3108 4.84e-87 260.0 COG3201@1|root,COG3201@2|Bacteria,1MXN4@1224|Proteobacteria,1RMZE@1236|Gammaproteobacteria,467GF@72275|Alteromonadaceae 1236|Gammaproteobacteria H nicotinamide mononucleotide transporter pnuC - - ko:K03811 - - - - ko00000,ko02000 4.B.1.1 - - NMN_transporter k141_3106_1 218284.CCDN010000001_gene1122 4.64e-115 331.0 COG5582@1|root,COG5582@2|Bacteria,1V5KV@1239|Firmicutes,4HEE0@91061|Bacilli,1ZB4J@1386|Bacillus 91061|Bacilli S Belongs to the UPF0302 family ypiB - - - - - - - - - - - IDEAL,UPF0302 k141_30316_1 1116375.VEJY3_24291 0.0 1687.0 COG0506@1|root,COG4230@1|root,COG0506@2|Bacteria,COG4230@2|Bacteria,1MV93@1224|Proteobacteria,1RN48@1236|Gammaproteobacteria,1XTWM@135623|Vibrionales 135623|Vibrionales C Oxidizes proline to glutamate for use as a carbon and nitrogen source putA - 1.2.1.88,1.5.5.2 ko:K13821 ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130 - R00245,R00707,R00708,R01253,R04444,R04445,R05051 RC00080,RC00083,RC00216,RC00242,RC00255 ko00000,ko00001,ko01000,ko03000 - - - Aldedh,Pro_dh,Pro_dh-DNA_bdg k141_30316_2 1116375.VEJY3_24296 8.67e-187 520.0 COG2207@1|root,COG2207@2|Bacteria,1REAN@1224|Proteobacteria,1S3P2@1236|Gammaproteobacteria,1XTWJ@135623|Vibrionales 135623|Vibrionales K COG2207 AraC-type DNA-binding domain-containing proteins - - - - - - - - - - - - AraC_binding,HTH_18,HTH_AraC k141_30316_3 1280001.BAOA01000075_gene3237 4.65e-125 373.0 COG3675@1|root,COG3675@2|Bacteria,1PI8G@1224|Proteobacteria,1RP6A@1236|Gammaproteobacteria,1XWYA@135623|Vibrionales 135623|Vibrionales I Lipase (class 3) - - - - - - - - - - - - Lipase_3 k141_30316_5 1219076.N646_3440 9.88e-150 421.0 COG0259@1|root,COG0259@2|Bacteria,1NZUU@1224|Proteobacteria,1RMQ2@1236|Gammaproteobacteria,1XUNP@135623|Vibrionales 135623|Vibrionales H Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) pdxH GO:0003674,GO:0003824,GO:0004733,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.4.3.5 ko:K00275 ko00750,ko01100,ko01120,map00750,map01100,map01120 M00124 R00277,R00278,R01710,R01711 RC00048,RC00116 ko00000,ko00001,ko00002,ko01000 - - - PNP_phzG_C,Putative_PNPOx k141_30316_6 35754.JNYJ01000036_gene3609 4.1e-96 336.0 COG1404@1|root,COG2931@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria,2GIRE@201174|Actinobacteria,4DGQR@85008|Micromonosporales 201174|Actinobacteria O Subtilase family mycP - 3.4.21.66 ko:K08651,ko:K14743 - - - - ko00000,ko01000,ko01002,ko03110 - - - Peptidase_S8 k141_30316_7 1116375.VEJY3_24316 1.84e-231 654.0 COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RQIN@1236|Gammaproteobacteria,1XTW1@135623|Vibrionales 135623|Vibrionales T COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system VVA1649 - 2.7.13.3 ko:K10125 ko02020,map02020 M00504 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,dCache_1 k141_7889_1 218284.CCDN010000001_gene1908 5.94e-77 249.0 COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1TPMS@1239|Firmicutes,4HAQD@91061|Bacilli,1ZATW@1386|Bacillus 91061|Bacilli NT COG0643 Chemotaxis protein histidine kinase and related kinases cheA - 2.7.13.3 ko:K03407 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt,P2 k141_14999_1 1123393.KB891316_gene1686 2.92e-54 186.0 COG0617@1|root,COG1371@1|root,COG0617@2|Bacteria,COG1371@2|Bacteria,1MU2X@1224|Proteobacteria,2VIN5@28216|Betaproteobacteria,1KRHG@119069|Hydrogenophilales 119069|Hydrogenophilales J Probable RNA and SrmB- binding site of polymerase A - - 2.7.7.72 ko:K00974 ko03013,map03013 - R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016 - - - Archease,HD,PolyA_pol,PolyA_pol_RNAbd k141_12856_1 218284.CCDN010000007_gene3913 2.36e-36 132.0 COG2133@1|root,COG2133@2|Bacteria,1TR38@1239|Firmicutes,4HBME@91061|Bacilli,1ZC94@1386|Bacillus 91061|Bacilli G COG2133 Glucose sorbosone dehydrogenases - - - - - - - - - - - - GSDH k141_18834_2 223926.28805062 0.0 869.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RRR1@1236|Gammaproteobacteria,1XV34@135623|Vibrionales 135623|Vibrionales K Bacterial regulatory protein, Fis family - - - - - - - - - - - - HTH_8,Sigma54_activat k141_18834_3 223926.28805063 1.86e-113 327.0 COG2823@1|root,COG2823@2|Bacteria,1PCIJ@1224|Proteobacteria,1RRGP@1236|Gammaproteobacteria,1XYNI@135623|Vibrionales 135623|Vibrionales S BON domain - - - - - - - - - - - - BON k141_18834_4 223926.28805064 4.03e-09 53.9 2AEPX@1|root,314K6@2|Bacteria,1R3GE@1224|Proteobacteria,1T67G@1236|Gammaproteobacteria,1Y1KD@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF1328) - - - - - - - - - - - - DUF1328 k141_18834_5 223926.28805065 1.9e-37 125.0 2EGUY@1|root,33AM4@2|Bacteria,1NGGE@1224|Proteobacteria,1RWJ8@1236|Gammaproteobacteria,1XZ5C@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_18834_6 223926.28805066 4.46e-97 282.0 COG5592@1|root,COG5592@2|Bacteria,1RGUY@1224|Proteobacteria,1S5V6@1236|Gammaproteobacteria,1Y0TG@135623|Vibrionales 135623|Vibrionales S Hemerythrin HHE cation binding domain - - - - - - - - - - - - Hemerythrin k141_18834_7 223926.28805067 0.0 999.0 COG1597@1|root,COG2453@1|root,COG1597@2|Bacteria,COG2453@2|Bacteria,1QSUD@1224|Proteobacteria,1RQAC@1236|Gammaproteobacteria,1XVX5@135623|Vibrionales 135623|Vibrionales IT Diacylglycerol kinase catalytic domain (presumed) - - - - - - - - - - - - DAGK_cat,DSPc k141_18834_8 223926.28805068 4.43e-85 251.0 29R0M@1|root,30C1R@2|Bacteria,1QMN8@1224|Proteobacteria,1TJXS@1236|Gammaproteobacteria,1Y1TV@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_18834_9 223926.28805069 1.61e-90 266.0 2DY9M@1|root,32V50@2|Bacteria,1QKPG@1224|Proteobacteria,1TITU@1236|Gammaproteobacteria,1XZN7@135623|Vibrionales 135623|Vibrionales S Domain of unknown function (DUF2383) - - - - - - - - - - - - DUF2383 k141_18834_10 223926.28805070 2.77e-47 154.0 2CHJ0@1|root,33FNQ@2|Bacteria,1NNVV@1224|Proteobacteria,1SGKA@1236|Gammaproteobacteria,1XZ9I@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_18834_11 223926.28805071 3.05e-108 313.0 2B56A@1|root,31Y06@2|Bacteria,1QK8J@1224|Proteobacteria,1TIC1@1236|Gammaproteobacteria,1XYUH@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_18834_13 223926.28805073 2.33e-207 578.0 COG0628@1|root,COG0628@2|Bacteria,1MXXU@1224|Proteobacteria,1RQCM@1236|Gammaproteobacteria,1XV4M@135623|Vibrionales 135623|Vibrionales S AI-2E family transporter - - - - - - - - - - - - AI-2E_transport k141_18834_14 1219076.N646_2271 2.13e-12 63.2 2EGUY@1|root,33AM4@2|Bacteria,1NGGE@1224|Proteobacteria,1RWJ8@1236|Gammaproteobacteria,1XZ5C@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_18834_15 1116375.VEJY3_00420 0.0 1274.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XSRH@135623|Vibrionales 135623|Vibrionales T signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - - - - - - - - - - EAL,GGDEF,PAS_3,PAS_9 k141_18834_16 1116375.VEJY3_00425 3.4e-187 523.0 COG0697@1|root,COG0697@2|Bacteria,1QSKQ@1224|Proteobacteria,1RYG1@1236|Gammaproteobacteria,1XV0H@135623|Vibrionales 135623|Vibrionales EG of the drug metabolite transporter (DMT) superfamily - - - - - - - - - - - - EamA k141_23581_1 634956.Geoth_2490 2.68e-83 255.0 COG1131@1|root,COG1131@2|Bacteria,1TPMQ@1239|Firmicutes,4HA8K@91061|Bacilli,1WG9T@129337|Geobacillus 91061|Bacilli V ATPases associated with a variety of cellular activities yfiL - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 k141_902_1 1128421.JAGA01000003_gene3517 8.54e-44 162.0 COG1193@1|root,COG1193@2|Bacteria,2NNS1@2323|unclassified Bacteria 2|Bacteria L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity mutS2 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K07456 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_V,Smr k141_11637_1 1294265.JCM21738_2492 1.54e-165 477.0 COG0465@1|root,COG0465@2|Bacteria,1V04C@1239|Firmicutes,4HF4A@91061|Bacilli,1ZDZ0@1386|Bacillus 91061|Bacilli O Peptidase family M41 - - - ko:K03798 - M00742 - - ko00000,ko00002,ko01000,ko01002,ko03110 - - - AAA,Peptidase_M41 k141_35361_2 1111730.ATTM01000002_gene948 7.2e-16 76.6 2EGMM@1|root,33ADT@2|Bacteria,4NUZ1@976|Bacteroidetes,1I52Q@117743|Flavobacteriia,2NXJH@237|Flavobacterium 976|Bacteroidetes S Bacterial PH domain - - - - - - - - - - - - bPH_4 k141_5695_1 1453501.JELR01000002_gene1014 6.22e-207 598.0 COG1199@1|root,COG1199@2|Bacteria,1MVRJ@1224|Proteobacteria,1RQ7B@1236|Gammaproteobacteria,464G6@72275|Alteromonadaceae 1236|Gammaproteobacteria KL COG1199 Rad3-related DNA helicases - - 3.6.4.12 ko:K10844 ko03022,ko03420,map03022,map03420 M00290 - - ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - DEAD_2,Helicase_C_2 k141_14155_1 1279017.AQYJ01000028_gene2511 0.0 1582.0 COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,1RPIU@1236|Gammaproteobacteria,46439@72275|Alteromonadaceae 1236|Gammaproteobacteria F COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ) carB GO:0000050,GO:0000166,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016053,GO:0016597,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b0033,iBWG_1329.BWG_0031,iECDH10B_1368.ECDH10B_0034,iECDH1ME8569_1439.ECDH1ME8569_0031,iECUMN_1333.ECUMN_0034,iEcDH1_1363.EcDH1_3566,iJN746.PP_4723,iJO1366.b0033,iJR904.b0033,iPC815.YPO0482,iY75_1357.Y75_RS00170,iYL1228.KPN_00041 CPSase_L_D2,CPSase_L_D3,MGS k141_14155_3 1453501.JELR01000002_gene405 1.04e-95 296.0 COG0845@1|root,COG0845@2|Bacteria,1MUG6@1224|Proteobacteria,1RP16@1236|Gammaproteobacteria,4680U@72275|Alteromonadaceae 1236|Gammaproteobacteria M Secretion protein - - - ko:K01993 - - - - ko00000 - - - Biotin_lipoyl_2,HlyD_3 k141_14155_4 743721.Psesu_3035 5.45e-137 397.0 COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,1RMM4@1236|Gammaproteobacteria,1X51T@135614|Xanthomonadales 135614|Xanthomonadales V ABC transporter - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_14155_5 1453501.JELR01000002_gene403 1.96e-148 428.0 COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,1RPB4@1236|Gammaproteobacteria,4655S@72275|Alteromonadaceae 1236|Gammaproteobacteria V ABC-2 family transporter protein ybhS - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 k141_23582_1 1453501.JELR01000001_gene2018 2.23e-103 325.0 COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,1RN05@1236|Gammaproteobacteria,464MR@72275|Alteromonadaceae 1236|Gammaproteobacteria S Insulinase (Peptidase family M16) ptrA - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C k141_12857_1 218284.CCDN010000001_gene565 4.34e-05 45.1 28KBQ@1|root,2Z9YP@2|Bacteria,1UZPB@1239|Firmicutes,4HAVU@91061|Bacilli,1ZBPJ@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_31477_1 203122.Sde_2844 9.07e-94 303.0 COG4676@1|root,COG4676@2|Bacteria,1NZI5@1224|Proteobacteria,1RP4G@1236|Gammaproteobacteria,466MN@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein conserved in bacteria - - - - - - - - - - - - CarboxypepD_reg k141_1867_1 301.JNHE01000002_gene2342 4.97e-21 93.2 COG0789@1|root,COG0789@2|Bacteria,1R9SN@1224|Proteobacteria,1S78T@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Transcriptional regulator - - - ko:K22491 - - - - ko00000,ko03000 - - - MerR_1 k141_1867_2 1453501.JELR01000001_gene3201 3.67e-160 457.0 COG1683@1|root,COG3272@1|root,COG1683@2|Bacteria,COG3272@2|Bacteria,1MXYZ@1224|Proteobacteria,1RNMF@1236|Gammaproteobacteria,464ZQ@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF1722) ybgA - - - - - - - - - - - DUF1722,DUF523 k141_1867_3 1279017.AQYJ01000022_gene2645 0.0 1689.0 COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,1RQX2@1236|Gammaproteobacteria,4649Q@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG0277 FAD FMN-containing dehydrogenases ydiJ - - - - - - - - - - - FAD-oxidase_C,FAD_binding_4,Fer4_8 k141_1867_9 1042377.AFPJ01000035_gene2599 1.31e-194 545.0 COG1054@1|root,COG1054@2|Bacteria,1MUFV@1224|Proteobacteria,1RNNU@1236|Gammaproteobacteria,464T0@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the UPF0176 family yceA - - ko:K07146 - - - - ko00000 - - - Rhodanese,Rhodanese_C k141_1867_11 1042377.AFPJ01000035_gene2603 0.0 1268.0 COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,1RMYM@1236|Gammaproteobacteria,463YC@72275|Alteromonadaceae 1236|Gammaproteobacteria J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation metG GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iEC042_1314.EC042_2346,iECUMN_1333.ECUMN_2446 Anticodon_1,tRNA-synt_1g,tRNA_bind k141_1867_12 1453501.JELR01000001_gene3212 8.1e-157 447.0 COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,1RPM1@1236|Gammaproteobacteria,464BE@72275|Alteromonadaceae 1236|Gammaproteobacteria CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family hprA - 1.1.1.29 ko:K00018 ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200 M00346 R00717,R01388 RC00031,RC00042 ko00000,ko00001,ko00002,ko01000 - - - 2-Hacid_dh,2-Hacid_dh_C k141_1867_13 1001530.BACE01000028_gene3909 2.08e-20 88.2 2E3K5@1|root,32YIE@2|Bacteria,1N9XS@1224|Proteobacteria,1SECD@1236|Gammaproteobacteria,1XZ5D@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_1867_14 1042377.AFPJ01000035_gene2607 7.86e-20 83.6 2CHJ0@1|root,33FNQ@2|Bacteria,1NNVV@1224|Proteobacteria,1SGKA@1236|Gammaproteobacteria,46C5Z@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - DUF883 k141_29507_2 994479.GL877878_gene598 3.37e-13 71.6 COG0597@1|root,COG0597@2|Bacteria,2GKRX@201174|Actinobacteria,4E3F6@85010|Pseudonocardiales 201174|Actinobacteria MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins lspA GO:0006464,GO:0006497,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009405,GO:0009987,GO:0019538,GO:0034645,GO:0036211,GO:0040007,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044419,GO:0051704,GO:0071704,GO:1901564,GO:1901566,GO:1901576 3.4.23.36 ko:K03101 ko03060,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_A8 k141_33009_1 42565.FP66_05070 3.67e-146 417.0 COG0559@1|root,COG0559@2|Bacteria,1MU25@1224|Proteobacteria,1RNDV@1236|Gammaproteobacteria,1XH8D@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the binding-protein-dependent transport system permease family - - - ko:K01997 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 k141_9497_1 218284.CCDN010000002_gene2156 1.98e-161 481.0 COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,4HAFP@91061|Bacilli,1ZBJ3@1386|Bacillus 91061|Bacilli V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family swrC - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran k141_37698_1 1247963.JPHU01000029_gene93 4.71e-52 172.0 COG2801@1|root,COG2801@2|Bacteria,1MVN5@1224|Proteobacteria,2TQK0@28211|Alphaproteobacteria 28211|Alphaproteobacteria L COG2801 Transposase and inactivated derivatives - - - - - - - - - - - - HTH_21,rve,rve_3 k141_21055_1 1033810.HLPCO_002516 7.89e-53 179.0 COG0651@1|root,COG0651@2|Bacteria,2NS4P@2323|unclassified Bacteria 2|Bacteria CP Proton-conducting membrane transporter nuoN - 1.6.5.3 ko:K00343,ko:K05568,ko:K12141 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000,ko02000 2.A.63.1,2.A.63.2,3.D.1 - - Proton_antipo_M k141_21055_2 1033810.HLPCO_002517 2.74e-202 573.0 COG0651@1|root,COG0651@2|Bacteria,2NR9Z@2323|unclassified Bacteria 2|Bacteria CP Proton-conducting membrane transporter ndhD5 - 1.6.5.3 ko:K05568,ko:K05575,ko:K12137 ko00190,ko01100,map00190,map01100 M00145 R11945 RC00061 ko00000,ko00001,ko00002,ko01000,ko02000 2.A.63.1,2.A.63.2 - iJN678.ndhD Proton_antipo_M k141_29508_2 218284.CCDN010000001_gene720 1.97e-104 309.0 COG0345@1|root,COG0345@2|Bacteria,1UZ3D@1239|Firmicutes,4HCJ6@91061|Bacilli,1ZBFA@1386|Bacillus 91061|Bacilli E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline comER - - ko:K02239 - M00429 - - ko00000,ko00002,ko02044 - - - F420_oxidored,P5CR_dimer k141_5857_1 1396.DJ87_2685 1.9e-28 126.0 COG4372@1|root,COG5280@1|root,COG5283@1|root,COG4372@2|Bacteria,COG5280@2|Bacteria,COG5283@2|Bacteria,1UHQM@1239|Firmicutes,4HGW7@91061|Bacilli,1ZBWW@1386|Bacillus 91061|Bacilli D phage tail tape measure protein - - - - - - - - - - - - Peptidase_M23,PhageMin_Tail,Sipho_tail k141_34281_1 1117647.M5M_18320 5.16e-105 330.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MV8W@1224|Proteobacteria,1RQEQ@1236|Gammaproteobacteria,1J4HT@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec k141_29509_2 218284.CCDN010000001_gene1757 1.48e-11 62.8 COG0546@1|root,COG0546@2|Bacteria,1V6BF@1239|Firmicutes,4HC3F@91061|Bacilli,1ZEAH@1386|Bacillus 91061|Bacilli F haloacid dehalogenase-like hydrolase - - - - - - - - - - - - HAD_2 k141_29509_3 218284.CCDN010000001_gene1757 7e-40 139.0 COG0546@1|root,COG0546@2|Bacteria,1V6BF@1239|Firmicutes,4HC3F@91061|Bacilli,1ZEAH@1386|Bacillus 91061|Bacilli F haloacid dehalogenase-like hydrolase - - - - - - - - - - - - HAD_2 k141_1131_1 1279017.AQYJ01000027_gene1655 9.17e-194 549.0 COG2223@1|root,COG2223@2|Bacteria,1MU27@1224|Proteobacteria,1RMUK@1236|Gammaproteobacteria,4640N@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG2223 Nitrate nitrite transporter narK - - ko:K02575 ko00910,map00910 M00615 - - ko00000,ko00001,ko00002,ko02000 2.A.1.8 - - MFS_1 k141_22534_1 218284.CCDN010000002_gene2251 1.76e-100 305.0 COG0069@1|root,COG0069@2|Bacteria,1TSHA@1239|Firmicutes,4HA97@91061|Bacilli,1ZCQH@1386|Bacillus 91061|Bacilli E Belongs to the glutamate synthase family yerD GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.7.1 ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 - R00021,R10086 RC00006,RC00010 ko00000,ko00001,ko01000 - - - Glu_synthase k141_17506_1 1279017.AQYJ01000026_gene55 1.93e-204 590.0 COG1049@1|root,COG1049@2|Bacteria,1MVCR@1224|Proteobacteria,1RNMC@1236|Gammaproteobacteria,46445@72275|Alteromonadaceae 1236|Gammaproteobacteria C Belongs to the aconitase IPM isomerase family acnB - 4.2.1.3,4.2.1.99 ko:K01682 ko00020,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173 R01324,R01325,R01900,R04425 RC00497,RC00498,RC00618,RC01153 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_2_N,Aconitase_B_N k141_5858_2 1121943.KB899989_gene3334 4.98e-20 88.2 COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,1RMMS@1236|Gammaproteobacteria,1XH4R@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the ferrous insertion into protoporphyrin IX hemH - 4.99.1.1,4.99.1.9 ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R00310,R11329 RC01012 ko00000,ko00001,ko00002,ko01000 - - - Ferrochelatase k141_2035_1 1042377.AFPJ01000036_gene1184 2.06e-113 340.0 COG0111@1|root,COG0111@2|Bacteria,1N5TD@1224|Proteobacteria,1RMFW@1236|Gammaproteobacteria,465GC@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate pdxB GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0033711,GO:0034641,GO:0036001,GO:0036094,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.1.1.290 ko:K03473 ko00750,ko01100,map00750,map01100 M00124 R04210 RC00084 ko00000,ko00001,ko00002,ko01000 - - iZ_1308.Z3582 2-Hacid_dh,2-Hacid_dh_C,DUF3410 k141_2035_3 1279017.AQYJ01000029_gene3344 4.65e-170 481.0 COG1092@1|root,COG1092@2|Bacteria,1PUHQ@1224|Proteobacteria,1RN8N@1236|Gammaproteobacteria,466G3@72275|Alteromonadaceae 1236|Gammaproteobacteria J S-adenosylmethionine-dependent methyltransferase - - 2.1.1.191 ko:K06969 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_SAM k141_2035_4 1453501.JELR01000001_gene2712 1.34e-69 212.0 2CU4K@1|root,32SUN@2|Bacteria,1N070@1224|Proteobacteria,1S979@1236|Gammaproteobacteria,46862@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_2035_5 1279017.AQYJ01000029_gene3346 1.01e-273 751.0 COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RN5B@1236|Gammaproteobacteria,465JB@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0436 Aspartate tyrosine aromatic aminotransferase alaA GO:0003674,GO:0003824,GO:0004021,GO:0005488,GO:0006082,GO:0006090,GO:0006520,GO:0006522,GO:0006523,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009078,GO:0009079,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019272,GO:0019752,GO:0019842,GO:0030170,GO:0030632,GO:0032787,GO:0033554,GO:0036094,GO:0042221,GO:0042851,GO:0042852,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046144,GO:0046145,GO:0046394,GO:0046416,GO:0046436,GO:0046437,GO:0046677,GO:0047635,GO:0048037,GO:0050662,GO:0050896,GO:0051716,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.2,2.6.1.66 ko:K14260 ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230 - R00258,R01215 RC00006,RC00008,RC00036 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 k141_2035_6 1042377.AFPJ01000036_gene1189 9.36e-81 241.0 COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,1S5WI@1236|Gammaproteobacteria,467FG@72275|Alteromonadaceae 1236|Gammaproteobacteria O Belongs to the MsrB Met sulfoxide reductase family msrB - 1.8.4.12 ko:K07305 - - - - ko00000,ko01000 - - - SelR k141_2035_7 76114.ebA2569 7.05e-45 159.0 COG4446@1|root,COG4446@2|Bacteria,1N31A@1224|Proteobacteria,2VV97@28216|Betaproteobacteria 28216|Betaproteobacteria S Protein of unknown function (DUF1499) - - - - - - - - - - - - DUF1499 k141_35585_1 221109.22779182 1.24e-05 45.1 29MV3@1|root,308SW@2|Bacteria,1U3X1@1239|Firmicutes,4IDPQ@91061|Bacilli,23MDW@182709|Oceanobacillus 91061|Bacilli S Protein of unknown function (DUF4025) - - - - - - - - - - - - DUF4025 k141_16450_2 796606.BMMGA3_01460 1.78e-90 269.0 COG0315@1|root,COG0315@2|Bacteria,1V3J4@1239|Firmicutes,4HH39@91061|Bacilli,1ZFIK@1386|Bacillus 91061|Bacilli H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) moaC - 4.6.1.17 ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R11372 RC03425 ko00000,ko00001,ko01000 - - - MoaC k141_5896_1 1453501.JELR01000002_gene746 6.06e-133 391.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPN9@1236|Gammaproteobacteria,464QS@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0488 ATPase components of ABC transporters with duplicated ATPase domains ybiT - - - - - - - - - - - ABC_tran,ABC_tran_Xtn k141_1151_1 218284.CCDN010000008_gene4214 5.09e-81 265.0 COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,4HA1S@91061|Bacilli,1ZAYY@1386|Bacillus 91061|Bacilli D Belongs to the FtsK SpoIIIE SftA family sftA - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_SpoIIIE,Ftsk_gamma k141_28134_2 696747.NIES39_H00600 1.61e-27 115.0 COG3769@1|root,COG3769@2|Bacteria,1G4FD@1117|Cyanobacteria,1H8XX@1150|Oscillatoriales 1117|Cyanobacteria S Mannosyl-3-phosphoglycerate phosphatase family - - 3.1.3.70 ko:K07026 ko00051,map00051 - R05790 RC00017 ko00000,ko00001,ko01000 - - - Hydrolase_3 k141_28134_3 1042377.AFPJ01000037_gene2985 2.72e-252 697.0 COG1215@1|root,COG1215@2|Bacteria,1MWH9@1224|Proteobacteria,1RPTN@1236|Gammaproteobacteria,4647V@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0463 Glycosyltransferases involved in cell wall biogenesis - - 2.4.1.266 ko:K13693 - - - - ko00000,ko01000,ko01003 - GT81 - - k141_21079_1 246199.CUS_6063 4.62e-19 87.0 COG0466@1|root,COG0466@2|Bacteria,1TNYG@1239|Firmicutes,247SH@186801|Clostridia,3WH4M@541000|Ruminococcaceae 186801|Clostridia O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner lon - 3.4.21.53 ko:K01338 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - AAA,LON_substr_bdg,Lon_C k141_17541_1 218284.CCDN010000006_gene3727 2.7e-138 395.0 COG1054@1|root,COG1054@2|Bacteria,1TRG7@1239|Firmicutes,4HA0J@91061|Bacilli,1ZCR7@1386|Bacillus 91061|Bacilli S Belongs to the UPF0176 family ybfQ - - ko:K07146 - - - - ko00000 - - - Rhodanese,Rhodanese_C k141_29531_2 218284.CCDN010000001_gene1386 2.07e-87 263.0 COG2176@1|root,COG2176@2|Bacteria,1V332@1239|Firmicutes,4HFP2@91061|Bacilli,1ZHN2@1386|Bacillus 91061|Bacilli L 3' exoribonuclease, RNase T-like - - 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - RNase_T k141_36437_1 42565.FP66_13645 1.68e-111 325.0 COG0583@1|root,COG0583@2|Bacteria,1MXXA@1224|Proteobacteria,1RREE@1236|Gammaproteobacteria,1XKAP@135619|Oceanospirillales 135619|Oceanospirillales K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate k141_35611_1 42565.FP66_14460 8.37e-30 114.0 28Q0R@1|root,2ZCJH@2|Bacteria,1RCAM@1224|Proteobacteria,1S3AM@1236|Gammaproteobacteria,1XJKX@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF3080) - - - - - - - - - - - - DUF3080 k141_35611_2 42565.FP66_14465 1.72e-30 113.0 28J4W@1|root,2Z90S@2|Bacteria,1R68N@1224|Proteobacteria,1RRQ2@1236|Gammaproteobacteria,1XJXP@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_20128_1 382464.ABSI01000012_gene2146 1.22e-50 179.0 COG1593@1|root,COG1593@2|Bacteria 2|Bacteria G mannitol 2-dehydrogenase activity - - - ko:K11690 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.56.1 - - DctM,DctQ k141_24828_2 574376.BAMA_19390 1.3e-79 238.0 COG0346@1|root,COG0346@2|Bacteria,1V5D6@1239|Firmicutes,4HI69@91061|Bacilli,1ZGTD@1386|Bacillus 91061|Bacilli E Glyoxalase-like domain - - 4.4.1.5,5.1.99.1 ko:K01759,ko:K05606 ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00620,map00630,map00640,map00720,map01100,map01120,map01200 M00373,M00375,M00376,M00741 R02530,R02765,R09979 RC00004,RC00740,RC00780,RC02739 ko00000,ko00001,ko00002,ko01000 - - - Glyoxalase,Glyoxalase_4 k141_24828_3 1122921.KB898192_gene2156 2.04e-07 54.3 COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,4HBD3@91061|Bacilli,26RCD@186822|Paenibacillaceae 91061|Bacilli G ABC-type sugar transport system, ATPase component rbsA3 - 3.6.3.17 ko:K02056 - M00221 - - ko00000,ko00002,ko01000,ko02000 3.A.1.2 - - ABC_tran k141_16451_1 218284.CCDN010000001_gene700 1.07e-132 391.0 COG0768@1|root,COG0768@2|Bacteria,1TQKI@1239|Firmicutes,4HC5S@91061|Bacilli,1ZBDB@1386|Bacillus 91061|Bacilli M Penicillin-binding Protein pbpI - - ko:K21468 - - - - ko00000,ko01011 - - - PBP_dimer,Transpeptidase k141_22568_1 1122194.AUHU01000004_gene1444 1.03e-115 348.0 COG0213@1|root,COG0213@2|Bacteria,1MV3H@1224|Proteobacteria,1RPTG@1236|Gammaproteobacteria,4661E@72275|Alteromonadaceae 1236|Gammaproteobacteria F The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis - - 2.4.2.4 ko:K00758 ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219 - R01570,R02484,R08222,R08230 RC00063 ko00000,ko00001,ko01000 - - - Glycos_trans_3N,Glycos_transf_3,PYNP_C k141_13025_1 218284.CCDN010000007_gene3926 4.91e-74 222.0 COG2120@1|root,COG2120@2|Bacteria,1VA8Q@1239|Firmicutes,4HKMK@91061|Bacilli,1ZH30@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF1806) yojF - - - - - - - - - - - DUF1806 k141_5897_1 1408424.JHYI01000008_gene1640 2.54e-56 201.0 COG0737@1|root,COG1404@1|root,COG2374@1|root,COG3391@1|root,COG0737@2|Bacteria,COG1404@2|Bacteria,COG2374@2|Bacteria,COG3391@2|Bacteria,1TPV2@1239|Firmicutes,4H9VJ@91061|Bacilli,1ZS4T@1386|Bacillus 91061|Bacilli F COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases cpdB - 3.1.3.5,3.1.3.6,3.1.4.16,3.6.1.45 ko:K01081,ko:K07004,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01562,R01569,R01664,R01877,R01968,R02088,R02102,R02148,R02323,R02370,R02719,R03346,R03537,R03538,R03929,R05135 RC00017,RC00078,RC00296 ko00000,ko00001,ko01000 - - - 5_nucleotid_C,CHB_HEX_C_1,Gram_pos_anchor,LTD,Metallophos,SLH k141_10533_1 218284.CCDN010000007_gene4020 3.97e-33 121.0 COG4786@1|root,COG4786@2|Bacteria,1TRFQ@1239|Firmicutes,4HCKG@91061|Bacilli,1ZBEC@1386|Bacillus 91061|Bacilli N flagellar basal body flhO GO:0001539,GO:0005575,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009424,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588 - ko:K02392 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C k141_10533_2 218284.CCDN010000007_gene4019 1.36e-72 226.0 COG1077@1|root,COG1077@2|Bacteria,1TP51@1239|Firmicutes,4HA4S@91061|Bacilli,1ZC87@1386|Bacillus 91061|Bacilli D Rod shape-determining protein mbl - - ko:K03569 - - - - ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 - - MreB_Mbl k141_28135_1 42565.FP66_12455 1.61e-129 378.0 COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,1RMSE@1236|Gammaproteobacteria,1XIBD@135619|Oceanospirillales 135619|Oceanospirillales EH COG0147 Anthranilate para-aminobenzoate synthases component I pabB - 2.6.1.85 ko:K01665 ko00790,map00790 - R01716 RC00010,RC01418 ko00000,ko00001,ko01000 - - - Anth_synt_I_N,Chorismate_bind k141_1152_1 218284.CCDN010000001_gene1600 5.35e-65 205.0 2A2R1@1|root,30R3Y@2|Bacteria,1U9MP@1239|Firmicutes,4IJT4@91061|Bacilli,1ZE7Q@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_24829_1 218284.CCDN010000005_gene3405 4.21e-130 382.0 COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,4HAAI@91061|Bacilli,1ZBC5@1386|Bacillus 91061|Bacilli S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family - - - ko:K03308 - - - - ko00000 2.A.22.4,2.A.22.5 - - SNF k141_11887_1 1123269.NX02_03665 2.94e-21 107.0 COG4206@1|root,COG4206@2|Bacteria,1R47X@1224|Proteobacteria,2TW6Q@28211|Alphaproteobacteria,2K1IJ@204457|Sphingomonadales 204457|Sphingomonadales H TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_17544_1 574376.BAMA_05670 8.33e-83 272.0 COG1404@1|root,COG1404@2|Bacteria,1TPH1@1239|Firmicutes,4HBQH@91061|Bacilli,1ZBS0@1386|Bacillus 91061|Bacilli O Belongs to the peptidase S8 family prtS - 3.4.21.110,3.4.21.96 ko:K01361,ko:K08652 - - - - ko00000,ko01000,ko01002,ko03110 - - - FIVAR,Gram_pos_anchor,Inhibitor_I9,PA,Peptidase_S8,SLH,YSIRK_signal,fn3_5 k141_34301_1 666686.B1NLA3E_04215 5.86e-27 107.0 COG2267@1|root,COG2267@2|Bacteria,1TSC4@1239|Firmicutes,4HBYX@91061|Bacilli,1ZEAA@1386|Bacillus 91061|Bacilli I hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - - - - - - - - - - Abhydrolase_1,Hydrolase_4 k141_34301_2 1196031.ALEG01000039_gene1146 7.53e-107 315.0 COG1028@1|root,COG1028@2|Bacteria,1TPIK@1239|Firmicutes,4HC6E@91061|Bacilli,1ZBHS@1386|Bacillus 91061|Bacilli IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 k141_29533_1 502025.Hoch_5031 1.12e-56 202.0 COG2374@1|root,COG2374@2|Bacteria,1MX52@1224|Proteobacteria,438DH@68525|delta/epsilon subdivisions,2WXQW@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Endonuclease/Exonuclease/phosphatase family - - - ko:K07004 - - - - ko00000 - - - Exo_endo_phos k141_2063_1 1294265.JCM21738_2009 2.03e-34 124.0 COG1013@1|root,COG1013@2|Bacteria,1UZ67@1239|Firmicutes,4IK6N@91061|Bacilli,1ZFE8@1386|Bacillus 91061|Bacilli C Thiamine pyrophosphate enzyme, C-terminal TPP binding domain - - - - - - - - - - - - TPP_enzyme_C k141_2063_2 1294265.JCM21738_2008 1.91e-108 314.0 COG1014@1|root,COG1014@2|Bacteria,1UYYG@1239|Firmicutes,4IK8K@91061|Bacilli,1ZFVM@1386|Bacillus 91061|Bacilli C Pyruvate ferredoxin/flavodoxin oxidoreductase - - - - - - - - - - - - POR k141_26157_2 1453501.JELR01000002_gene1066 1.15e-06 50.1 COG1999@1|root,COG1999@2|Bacteria,1RHJ8@1224|Proteobacteria,1SYEA@1236|Gammaproteobacteria,46CW7@72275|Alteromonadaceae 1236|Gammaproteobacteria S SCO1/SenC - - - ko:K07152 - - - - ko00000,ko03029 - - - SCO1-SenC k141_24830_1 1294265.JCM21738_3976 7.87e-188 525.0 COG1164@1|root,COG1164@2|Bacteria,1TQ5W@1239|Firmicutes,4HAN9@91061|Bacilli,1ZCRR@1386|Bacillus 91061|Bacilli E COG1164 Oligoendopeptidase F pepF2 - - - - - - - - - - - Peptidase_M3,Peptidase_M3_N k141_22571_2 218284.CCDN010000007_gene3789 8.75e-05 43.9 COG1195@1|root,COG1195@2|Bacteria,1TP9U@1239|Firmicutes,4HA0W@91061|Bacilli,1ZC8V@1386|Bacillus 91061|Bacilli L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP recF GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - ko:K03629 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - SMC_N k141_3305_1 1279017.AQYJ01000029_gene3406 9.72e-60 202.0 COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,1RPAV@1236|Gammaproteobacteria,463XQ@72275|Alteromonadaceae 1236|Gammaproteobacteria L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA ligA GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003909,GO:0003911,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0034645,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050662,GO:0050896,GO:0051103,GO:0051287,GO:0051716,GO:0070403,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1901576 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - iEC55989_1330.EC55989_2701,iECABU_c1320.ECABU_c27320,iECIAI1_1343.ECIAI1_2469,iECO103_1326.ECO103_2930,iECO111_1330.ECO111_3141,iECO26_1355.ECO26_3464,iECSE_1348.ECSE_2702,iECW_1372.ECW_m2640,iEKO11_1354.EKO11_1317,iEcE24377_1341.EcE24377A_2698,iEcSMS35_1347.EcSMS35_2566,iWFL_1372.ECW_m2640,iYL1228.KPN_02758,ic_1306.c2945 BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5 k141_28137_1 218284.CCDN010000007_gene3914 1.05e-79 246.0 COG1957@1|root,COG1957@2|Bacteria,1TRDA@1239|Firmicutes,4HDED@91061|Bacilli,1ZQTI@1386|Bacillus 91061|Bacilli F Inosine-uridine preferring nucleoside hydrolase - - 3.2.2.1 ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 - R01245,R01273,R01677,R01770,R02143 RC00033,RC00063,RC00122,RC00318,RC00485 ko00000,ko00001,ko01000 - - - IU_nuc_hydro k141_28137_2 218284.CCDN010000007_gene3913 1.91e-13 68.9 COG2133@1|root,COG2133@2|Bacteria,1TR38@1239|Firmicutes,4HBME@91061|Bacilli,1ZC94@1386|Bacillus 91061|Bacilli G COG2133 Glucose sorbosone dehydrogenases - - - - - - - - - - - - GSDH k141_5899_2 218284.CCDN010000001_gene1809 1.17e-92 276.0 COG0586@1|root,COG0586@2|Bacteria,1V76Y@1239|Firmicutes,4HJKU@91061|Bacilli,1ZFU6@1386|Bacillus 91061|Bacilli S SNARE associated Golgi protein - - - - - - - - - - - - SNARE_assoc k141_2065_1 218284.CCDN010000005_gene3412 7.58e-41 138.0 COG2445@1|root,COG2445@2|Bacteria,1V6HM@1239|Firmicutes,4HITV@91061|Bacilli,1ZGY2@1386|Bacillus 91061|Bacilli S Protein of unknown function DUF86 yutE - - - - - - - - - - - DUF86 k141_2065_2 218284.CCDN010000005_gene3413 2.3e-11 62.4 COG0647@1|root,COG0647@2|Bacteria,1TQGM@1239|Firmicutes,4HA3R@91061|Bacilli,1ZB73@1386|Bacillus 91061|Bacilli G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro nagD - 3.1.3.41 ko:K01101 ko00627,ko01120,map00627,map01120 - R03024 RC00151 ko00000,ko00001,ko01000 - - - Hydrolase_6,Hydrolase_like k141_22572_1 218284.CCDN010000004_gene3102 3.22e-99 294.0 COG1028@1|root,COG1028@2|Bacteria,1TP3G@1239|Firmicutes,4HACT@91061|Bacilli,1ZDEW@1386|Bacillus 91061|Bacilli IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate - - 1.1.1.30 ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 M00088 R01361 RC00117 ko00000,ko00001,ko00002,ko01000 - - - adh_short_C2 k141_11889_1 218284.CCDN010000001_gene594 6.38e-244 688.0 COG0466@1|root,COG0466@2|Bacteria,1TNYG@1239|Firmicutes,4HAZK@91061|Bacilli,1ZAXX@1386|Bacillus 91061|Bacilli O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner lon GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.4.21.53 ko:K01338 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - AAA,LON_substr_bdg,Lon_C k141_24831_2 1196031.ALEG01000028_gene4078 1.26e-40 140.0 2CC7N@1|root,344W2@2|Bacteria,1VYRU@1239|Firmicutes,4HYJ0@91061|Bacilli,1ZFXC@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_29535_1 218284.CCDN010000006_gene3670 1.69e-98 300.0 COG0793@1|root,COG0793@2|Bacteria,1TPBI@1239|Firmicutes,4HAKE@91061|Bacilli,1ZBDE@1386|Bacillus 91061|Bacilli M Belongs to the peptidase S41A family ctpB GO:0003674,GO:0003824,GO:0004175,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008233,GO:0009653,GO:0009987,GO:0016787,GO:0019538,GO:0023052,GO:0030154,GO:0030288,GO:0030313,GO:0030435,GO:0031975,GO:0032502,GO:0033218,GO:0034641,GO:0042277,GO:0042597,GO:0042802,GO:0042803,GO:0043170,GO:0043603,GO:0043900,GO:0043902,GO:0043934,GO:0044237,GO:0044238,GO:0044464,GO:0046983,GO:0048518,GO:0048522,GO:0048646,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070011,GO:0071704,GO:0140096,GO:1900190,GO:1900192,GO:1901564 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - PDZ,PDZ_2,PG_binding_1,Peptidase_S41 k141_17545_1 218284.CCDN010000012_gene4433 2.9e-178 501.0 28JUG@1|root,2Z9JI@2|Bacteria,1UYYT@1239|Firmicutes,4HC3E@91061|Bacilli,1ZBYK@1386|Bacillus 91061|Bacilli S YaaC-like Protein yaaC - - - - - - - - - - - YaaC k141_5900_2 1042377.AFPJ01000028_gene2261 2.24e-67 209.0 COG5589@1|root,COG5589@2|Bacteria,1NGHI@1224|Proteobacteria,1SGFT@1236|Gammaproteobacteria,468Z5@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF2390) - - - - - - - - - - - - DUF2390 k141_20133_1 218284.CCDN010000001_gene1150 2.66e-230 659.0 COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H9SA@91061|Bacilli,1ZAXY@1386|Bacillus 91061|Bacilli M penicillin-binding protein ponA GO:0005575,GO:0005576 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase k141_16455_1 1003195.SCAT_2851 2.25e-13 69.3 COG2072@1|root,COG2072@2|Bacteria,2GKBD@201174|Actinobacteria 201174|Actinobacteria P FAD dependent oxidoreductase - - - - - - - - - - - - Pyr_redox_3 k141_16455_2 1121920.AUAU01000006_gene267 1.78e-35 125.0 COG0640@1|root,COG0640@2|Bacteria 2|Bacteria K DNA-binding transcription factor activity arsR - - - - - - - - - - - HTH_20,HTH_5 k141_22574_2 1042377.AFPJ01000007_gene1907 2.45e-12 69.3 2EC19@1|root,3360G@2|Bacteria,1N87W@1224|Proteobacteria,1S7E3@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Peptidoglycan-binding protein, CsiV pgs1 - - - - - - - - - - - CsiV k141_1153_1 1280001.BAOA01000021_gene738 2.64e-104 308.0 COG1494@1|root,COG1494@2|Bacteria,1MUB1@1224|Proteobacteria,1RR0E@1236|Gammaproteobacteria,1XTI1@135623|Vibrionales 135623|Vibrionales G COG1494 Fructose-1,6-bisphosphatase sedoheptulose 1,7-bisphosphatase and related proteins glpX - 3.1.3.11 ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 M00003,M00165,M00167 R00762,R04780 RC00017 ko00000,ko00001,ko00002,ko01000 - - - FBPase_glpX k141_1153_2 1116375.VEJY3_01220 1.62e-131 374.0 COG2345@1|root,COG2345@2|Bacteria,1RDXT@1224|Proteobacteria,1S4DW@1236|Gammaproteobacteria,1XTKY@135623|Vibrionales 135623|Vibrionales K Transcriptional regulator - - - - - - - - - - - - HTH_11,HTH_24,HTH_DeoR k141_1153_3 1116375.VEJY3_01215 2.26e-50 162.0 2EM8V@1|root,33EY0@2|Bacteria,1NBBF@1224|Proteobacteria,1SDDM@1236|Gammaproteobacteria,1XYUC@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF3135) VV3022 - - - - - - - - - - - DUF3135 k141_1153_4 1547445.LO80_09630 1.81e-24 94.4 COG2827@1|root,COG2827@2|Bacteria,1MZME@1224|Proteobacteria,1S8Z1@1236|Gammaproteobacteria,462MC@72273|Thiotrichales 72273|Thiotrichales L GIY-YIG catalytic domain - - - ko:K07461 - - - - ko00000 - - - GIY-YIG k141_2067_1 1463885.KL578355_gene10332 3e-15 78.6 COG0454@1|root,COG0456@2|Bacteria,2IK8Z@201174|Actinobacteria 201174|Actinobacteria K Acetyltransferase (GNAT) family - - - - - - - - - - - - Acetyltransf_1 k141_21086_1 1324957.K933_10904 1.18e-08 55.5 COG2421@1|root,arCOG01004@2157|Archaea,2XU60@28890|Euryarchaeota,23S6B@183963|Halobacteria 183963|Halobacteria C acetamidase formamidase - - - - - - - - - - - - FmdA_AmdA k141_21086_2 215803.DB30_3169 4.64e-38 143.0 COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,42NU9@68525|delta/epsilon subdivisions,2WKXG@28221|Deltaproteobacteria,2YWEG@29|Myxococcales 28221|Deltaproteobacteria C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - - - - - - - - - - Ald_Xan_dh_C2 k141_28139_1 203120.LEUM_1152 2.48e-11 64.7 COG1116@1|root,COG1116@2|Bacteria,1TRE2@1239|Firmicutes,4HAHM@91061|Bacilli,4AXWJ@81850|Leuconostocaceae 91061|Bacilli P ATPases associated with a variety of cellular activities ssuB - - ko:K02049,ko:K15555 ko00920,ko02010,map00920,map02010 M00188,M00436 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.16,3.A.1.17,3.A.1.17.2 - - ABC_tran k141_35618_1 1121090.KB894709_gene1587 1.42e-96 289.0 COG1957@1|root,COG1957@2|Bacteria,1TSAR@1239|Firmicutes,4HDCS@91061|Bacilli,1ZD4R@1386|Bacillus 91061|Bacilli F nucleoside hydrolase - - 3.2.2.1 ko:K01239,ko:K01250 ko00230,ko00760,ko01100,map00230,map00760,map01100 - R01245,R01273,R01677,R01770,R02143 RC00033,RC00063,RC00122,RC00318,RC00485 ko00000,ko00001,ko01000 - - - IU_nuc_hydro k141_24832_1 218284.CCDN010000001_gene1506 3.23e-212 610.0 COG1048@1|root,COG1048@2|Bacteria,1VTMM@1239|Firmicutes,4HB5N@91061|Bacilli,1ZART@1386|Bacillus 91061|Bacilli C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate citB GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0043937,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0050789,GO:0050793,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0065007,GO:0071704,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_C k141_2068_2 1294265.JCM21738_3835 3.17e-39 136.0 COG0600@1|root,COG0600@2|Bacteria,1TR9N@1239|Firmicutes,4HC2U@91061|Bacilli,1ZQFP@1386|Bacillus 91061|Bacilli P Binding-protein-dependent transport system inner membrane component ssuC_2 - - ko:K02050,ko:K15554 ko00920,ko02010,map00920,map02010 M00188,M00436 - - ko00000,ko00001,ko00002,ko02000 3.A.1.16,3.A.1.17,3.A.1.17.2 - - BPD_transp_1 k141_5922_1 1504981.KO116_2779 3.16e-54 183.0 COG1670@1|root,COG1670@2|Bacteria,1MWIE@1224|Proteobacteria,1S2ID@1236|Gammaproteobacteria,1XK3B@135619|Oceanospirillales 135619|Oceanospirillales J Siderophore biosynthesis protein domain - - 2.3.1.102 ko:K03896 ko00310,ko01120,map00310,map01120 - R03168 RC00004,RC00865 ko00000,ko00001,ko01000 - - - Acetyltransf_8 ## 27633 queries scanned ## Total time (seconds): 109.25859880447388 ## Rate: 252.91 q/s